gebhart/patrepeval huggingface dataset:
Inkjet printing of upconversion nanoparticles for anti-counterfeit applications (2015)

Patterning of upconversion luminescent materials has been widely used for anti-counterfeit and security applications, where the preferred method should be easy, fast, multicolor, high-throughput and designable. However, conventional patterning methods are complex and inflexible. Here, we report a digital and flexible inkjet printing based approach for producing high-resolution and high-luminescence anti-counterfeit patterns. We successfully printed different multicolor luminescent patterns by inkjet printing of upconversion nanoparticles with controlled and uniform luminescence intensity through optimizing the inks and substrates. Combined with another downconversion luminescent material, we achieved two different patterns in the same area, which show up separately under excitation by different wavelength laser sources. The developed technology is promising to use one single substrate for carrying abundant information by printing multilayer patterns composed of luminescent materials with different excitation light sources.
Application of Ti salicide process on ultra-thin SIMOX wafer (2002)

Fully-depleted, ultra-thin SIMOX/CMOS is a suitable technology to achieve low voltage and high speed application because of its capability of low Vth operation. However, large resistivity of diffusion area is an issue. In this paper,a thin salicidation layer was adopted to decrease the sheet resistivity of the ultra-thin SIMOX layer. Good transistor characteristics with sheet resistivity less than one tenth of the non-silicided diffusion resistivity were achieved, and no degradation of the transistor characteristics was observed.
An NGF-TrkA-Mediated Retrograde Signal to Transcription Factor CREB in Sympathetic Neurons (1997)

Nerve growth factor (NGF) is a neurotrophic factor secreted by cells that are the targets of innervation of sympathetic and some sensory neurons. However, the mechanism by which the NGF signal is propagated from the axon terminal to the cell body, which can be more than 1 meter away, to influence biochemical events critical for growth and survival of neurons has remained unclear. An NGF-mediated signal transmitted from the terminals and distal axons of cultured rat sympathetic neurons to their nuclei regulated phosphorylation of the transcription factor CREB (cyclic adenosine monophosphate response element-binding protein). Internalization of NGF and its receptor tyrosine kinase TrkA, and their transport to the cell body, were required for transmission of this signal. The tyrosine kinase activity of TrkA was required to maintain it in an autophosphorylated state upon its arrival in the cell body and for propagation of the signal to CREB within neuronal nuclei. Thus, an NGF-TrkA complex is a messenger that delivers the NGF signal from axon terminals to cell bodies of sympathetic neurons.
Clustering of Vehicle Trajectories (2010)

We present a method that is suitable for clustering of vehicle trajectories obtained by an automated vision system. We combine ideas from two spectral clustering methods and propose a trajectory-similarity measure based on the Hausdorff distance, with modifications to improve its robustness and account for the fact that trajectories are ordered collections of points. We compare the proposed method with two well-known trajectory-clustering methods on a few real-world data sets.
Antiplatelet aggregation activity of compounds isolated from Guttiferae species in human whole blood (2009)

Twenty compounds isolated from Calophyllum inophyllum L., C. inophylloides King, Garcinia opaca King, G. bancana Miq., and G. parvifolia Miq. (Guttiferae) were evaluated for their ability to inhibit platelet aggregation in human whole blood induced by arachidonic acid (AA), collagen, and adenosine diphosphate (ADP). The compounds inhibited platelet aggregation in a dose-dependent manner. Among the compounds tested, 2-(3-methylbut-2-enyl)-1,3,5-trihydroxyxanthone and 2-(3-methylbut-2-enyl)-1,3,5,6- tetrahydroxyxanthone showed strong inhibitory activity on platelet aggregation induced by AA with IC50 values of 115.9 and 113.0 μM, respectively. Rubraxanthone showed inhibitory activity against aggregation caused by the three inducers, and was the most effective antiplatelet compound against collagen-induced platelet aggregation with an IC50 value of 47.0 μM. Macluraxanthone, GB-1a, pyranoamentoflavone, and a neoflavonoid showed selective inhibitory activity on platelet aggregation induced by ADP.
A framework to integrate synchronous and asynchronous collaboration (2002)

For the last decade, the research in CSCW (computer supported cooperative work) has been focusing on synchronous collaboration, which requires the participants involved in common tasks to remotely share computer display workspaces simultaneously without leaving their workplaces. However, to support truly global cooperative work, asynchronous collaboration is equally prominent, in order to accommodate the participants who may not be available for the synchronous CSCW session. These participating individuals, whether working synchronously or asynchronously, may be mobile and may have to connect to and disconnect from the session repeatedly with ubiquitous systems. We describe a framework for asynchronous as well as synchronous collaboration. The framework provides facilities to transfer the screen images or frame buffers of the ongoing CSCW session to remote users, allowing the available participants to share the view and the control of the session simultaneously, and to record the screen images or frame buffers for the absent participants to retrieve and playback the session at a later stage with VCR-like control (i.e. fast forward, rewind play and stop). The frame buffers are transferred and recorded in units of rectangles containing pixel values of the screen images. These rectangles are platform independent and can be dynamically directed to and displayed by heterogeneous systems such as X Windows or Windows NT, or by Web browser such as Netscape.
Predictions of Adiabatic Film Cooling Effectiveness for Effusion Film Cooling (2007)

This paper presents computational predictions of adiabatic film cooling effectiveness for effusion cooling systems with 90° and 30° holes. Predictions are performed for a range of coolant injection mass flow rates per unit surface area, G, of 0.1kg/sm2 - 1.6 kg/sm2 for 90° holes with constant pitch-to-diameter ratio of X/D = 11 and 10 rows of holes and for 30° inclined holes with X/D = 11 and 15 rows of holes over a 152mm surface length. The computational works performed are steady-state and the turbulent governing equations are solved by a control-volume-based finite difference method with second-order upwind scheme and the k-epsilon turbulence model. The velocity and pressure terms of momentum equations are solved by the SIMPLE method. The CFD prediction were validated by comparing the predictions with literature data for single rows of inclined holes and then applied to effusion cooling. The predictions included the use of a tracer gas in the coolant, which was used to predict the mixing of the coolant with the hot mainstream gases. Also the surface distribution of the tracer gas was a direct prediction of the cooling effectiveness. The mixing of coolant with the mainstream was studied and boundary layer temperature and coolant mixing profiles were predicted. These were compared with temperature measurement in a hot effusion cooling test rig.
Differential expression patterns of cytokines in complex regional pain syndrome (2007)

Complex regional pain syndromes (CRPS) are characterized by persistent and severe pain after trauma or surgery. Neuro-immune alterations are assumed to play a pathophysiological role. Here we set out to investigate whether patients with CRPS have altered systemic pro- and anti-inflammatory cytokine profiles compared to controls on mRNA and protein level. We studied blood cytokine mRNA and protein levels of the pro-inflammatory cytokines tumor necrosis factor-alpha (TNF), interleukin-2 (IL-2) and IL-8 and the anti-inflammatory cytokines IL-4, IL-10, and transforming growth factor-beta1 (TGF beta 1) in 40 prospectively recruited patients with CRPS I, two patients with CRPS II, and 34 controls. Quantitative real-time PCR and enzyme linked immunosorbent assay were used. Additionally, the patients underwent quantitative sensory testing and were assessed with the McGill pain questionnaire and the Hospital anxiety and depression scale. Patients with CRPS had higher blood TNF and IL-2 mRNA levels (p=0.005; p=0.04) and lower IL-8 mRNA levels (p<0.001) than controls. The mRNA for the anti-inflammatory cytokines IL-4 and IL-10 was reduced in the patient group (p=0.004; p=0.006), whereas TGF beta 1 mRNA levels did not differ between groups. These results were paralleled by serum protein levels, except for TGF beta 1, which was reduced in patients with CRPS, and for IL-8, which gave similar protein values in both groups. Sensory testing showed a predominant loss of small fiber-related modalities in the patient group. The shift towards a pro-inflammatory cytokine profile in patients with CRPS suggests a potential pathogenic role in the generation of pain.
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage (2007)

The Brca1 A complex contains Brca1/Bard1, Abraxas, Rap80, and Brcc36; however, with the exception of the Brca1-Abraxas interaction, how the A complex is assembled is not known. The A complex is localized to sites of DNA damage through the UIM domains of RAP80, which bind K63-linked polyubiquitin chains. In this study, we identified an FHA domain RING finger E3 ubiquitin ligase, RNF8, and an E2-conjugating enzyme known to form K63-polyubiquitin chains, Ubc13, each of which is required to recruit the Brca1 A complex to sites of DNA damage. Rnf8 localizes to sites of DNA damage through an FHA-domain-containing region. We found that Rap80 contains an Abraxas interaction domain [AIR (Abraxas-interacting region)], required for association of Rap80 with Abraxas, Brca1, and Brcc36. Abraxas and Brcc36 associate through coiled-coil domains on each protein. These data suggest a model through which Ubc13 and Rnf8 are recruited to sites of DNA damage through DNA-damage-induced phosphorylation of a chromatin-associated protein and generate polyubiquitin chains that then recruit Rap80 and the entire Brca1 A complex to DNA-damage foci. This sequential E3 ubiquitin ligase recruitment constitutes a ubiquitin ligase cascade required for DNA repair and checkpoint signaling.
Maximizing Ion-Tagged Oligonucleotide Loading on Magnetic Ionic Liquid Supports for the Sequence-Specific Extraction of Nucleic Acids (2019)

Targeted nucleic acid analysis requires the highly selective extraction of desired DNA fragments in order to minimize interferences from samples with abundant heterogeneous sequences. We previously reported a method based on functionalized oligonucleotide probes known as ion-tagged oligonucleotides (ITOs) that hybridize with complementary DNA targets for subsequent capture using a hydrophobic magnetic ionic liquid (MIL) support. Although the ITO-MIL approach enriched specific DNA sequences in quantities comparable to a commercial magnetic bead-based method, the modest affinity of the ITO for the hydrophobic MIL limited the yield of DNA targets, particularly when stringent wash conditions were applied to remove untargeted DNA. Here, we report the synthesis and characterization of a series of ITOs in which functional groups were installed within the cation and anion components of the tag moiety in order to facilitate loading of the ITO to the MIL support phase. In addition to hydrophobic interactions, we demonstrate that π-π stacking and fluorophilic interactions can be exploited for loading oligonucleotide probes onto MILs. Using a disubstituted ion-tagged oligonucleotide (DTO) possessing two linear C<sub>8</sub> groups, nearly quantitative loading of the probe onto the MIL support was achieved. The enhanced stability of the DTO within the MIL solvent permitted successive wash steps without the loss of the DNA target compared to a monosubstituted ITO with a single C<sub>8</sub> group that was susceptible to increased loss of analyte. Furthermore, the successful capture of a 120 bp KRAS fragment from human plasma samples followed by real-time quantitative polymerase chain reaction (qPCR) amplification is demonstrated.
Ion-recombination correction for different ionization chambers in high dose rate flattening-filter-free photon beams (2012)

Recently, there has been an increased interest in flattening-filter-free (FFF) linear accelerators. Removal of the filter results in available dose rates up to 24 Gy min(-1) (for nominal energy 10 MV in depth of maximum dose, a source-surface distance of 100 cm and a field size of 10×10 cm2). To guarantee accurate relative and reference dosimetry for the FFF beams, we investigated the charge collection efficiency of multiple air-vented and one liquid ionization chamber for dose rates up to 31.9 Gy min(-1). For flattened beams, the ion-collection efficiency of all air-vented ionization chambers (except for the PinPoint chamber) was above 0.995. By removing the flattening filter, we found a reduction in collection efficiency of approximately 0.5-0.9% for a 10 MV beam. For FFF beams, the Markus chamber showed the largest collection efficiency of 0.994. The observed collection efficiencies were dependent on dose per pulse, but independent of the pulse repetition frequency. Using the liquid ionization chamber, the ion-collection efficiency for flattened beams was above 0.990 for all dose rates. However, this chamber showed a low collection efficiency of 0.940 for the FFF 10 MV beam at a dose rate of 31.9 Gy min(-1). All investigated air-vented ionization chambers can be reliably used for relative dosimetry of FFF beams. The order of correction for reference dosimetry is given in the manuscript. Due to their increased saturation in high dose rate FFF beams, liquid ionization chambers appear to be unsuitable for dosimetry within these contexts.
Chemical Modulation of Work Function as a Transduction Mechanism for Chemical Sensors (1998)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemical Modulation of Work Function as a Transduction Mechanism for Chemical SensorsJiřÍ Janata and Mira JosowiczView Author Information School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400 Cite this: Acc. Chem. Res. 1998, 31, 5, 241–248Publication Date (Web):April 11, 1998Publication History Received19 May 1997Published online11 April 1998Published inissue 1 May 1998https://pubs.acs.org/doi/10.1021/ar9700668https://doi.org/10.1021/ar9700668research-articleACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views821Altmetric-Citations88LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Charge transfer,Layers,Palladium,Silicon,Work function Get e-Alerts
Effects of hormones and growth factors on TGF-β1 expression in bovine mammary epithelial cells (2005)

The decline of mammary epithelial cell (MEC) number during mammary gland involution in the cow is due to inhibition of proliferation and induction of apoptosis. Transforming growth factor-beta 1 (TGF-beta1) belongs to a group of intramammary auto/paracrine inhibitors of bovine MEC growth and inducers of apoptosis. However, the mechanism responsible for the regulation of TGF-beta1 expression in MEC is not known. The present study examined the effect of the hormones, growth hormone (GH), somatostatin (STS), 17-beta oestradiol (E2), progesterone (P4), as well as the growth factors, insulin-like growth factor I (IGF-I) and epidermal growth factor (EGF), on TGF-beta1 expression in the bovine MEC lines, BME-UV1 and MAC-T. The model of apoptosis in bovine mammary gland in vitro was applied by reduction of fetal bovine serum (FBS) (from 10% to 2% or 0.5% FBS) in the cell environment to show the relationship between TGF-beta1 expression and apoptosis in bovine MEC. RT-PCR, Western blot and laser scanning cytometry (LSC) were used for analysis of TGF-beta1 transcript and protein level as well as apoptosis and cell cycle in examined MEC. In this model of apoptosis, FBS deficiency (mimicking the naturally occurring decline in the access of bioactive compounds and nutrients at the end of lactation and dry period) was associated with increased TGF-beta1 expression at the level of transcript and protein, induction of apoptosis and inhibition of cell cycle. Exogenous TGF-beta1, IGF-I, EGF and GH inhibited FBS-deficiency-stimulated TGF-beta1 expression. The suppressive effect of GH was reversed when cells were maintained longer in FBS-deficient medium. In general, STS, E2 and P4 increased TGF-beta1 expression. However, this effect was dependent on hormone concentration and cell line. BME-UV1 cells were much more responsive to the peptides, GH, STS, IGF-I and EGF, whereas MAC-T cells were more responsive to the steroid sex hormones: E2 and P4.
Péripéties de la politique d'Etat pour l'égalité des chances en France (1998)

Cet article montre comment le feminisme d'Etat, defini comme la politique publique de promotion de l'egalite des sexes developpee par l'Etat a partir du milieu des annees soixante, a integre et englobe les femmes en milieu rural. Il rend compte des principales etapes de l'action publique en direction de femmes dont l'identite apparait comme oscillant entre le territoire et la profession, entre la citoyennete et le pouvoir, le collectif ou le domestique.
Reaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2‘-Hydroxypropiophenones and Related β-Diketones (1996)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTReaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2'-Hydroxypropiophenones and Related β-DiketonesJoel Morris, George P. Luke, and Donn G. WishkaView Author Information Discovery Chemistry Research, Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001 Cite this: J. Org. Chem. 1996, 61, 9, 3218–3220Publication Date (Web):May 3, 1996Publication History Received15 December 1995Published online3 May 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jo952213qhttps://doi.org/10.1021/jo952213qbrief-reportACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views524Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Acid and base chemistry,Anions,Boron,Lewis acids,Reaction products Get e-Alerts
Simultaneous Attainment of Low Fuel Consumption High Output Power and Low Exhaust Emissions in Direct Injection SI Engines (1998)

<div class="htmlview paragraph">This paper describes simultaneous attainment in improving fuel consumption, output power and reducing HC emissions with a direct injection S.I. engine newly developed in Nissan.</div> <div class="htmlview paragraph">Straight intake port is adopted to increase discharge coefficient under WOT operation and horizontal swirl flow is generated by a swirl control valve to provide stable stratified charge combustion under part load conditions. As a result, fuel consumption is reduced by more than 20% and power output is improved by approximately 10%. Moreover, unburned HC is reduced by equivalently 30% in engine cold start condition. An application of diagnostic and numerical simulation tools to investigate and optimize various factors are also introduced.</div>
Application of wavelet transform-based discharging/charging voltage signal denoising for advanced data-driven SOC estimator (2015)

Unexpected sensing of noisy discharging/charging voltage of a Li-Ion cell may result in erroneous state-of-charge (SOC) estimation and low battery management system (BMS) performance. Therefore, this study gives insight to the design and implementation of the discrete wavelet transform (DWT)- based denoising technique for noise reduction of the DCV. The steps of denoising of noisy DCV for proposed study are follows. Firstly, by using the multi-resolution analysis (MRA), the noise-riding DCV signal is decomposed into different frequency subbands. Specifically, the signal processing considering high frequency component that focuses on short-time interval is absolutely necessary in order to reduce noise of the DCV. Secondly, the hard-thresholding based denoising technique is used to adjust the wavelet coefficients of the DWT for a clear separation between the signal and the noise. Thirdly, the desired de-noised DCV signal is reconstructed by taking the inverse DWT on filtered detailed coefficients. Consequently, this signal is applied to the equivalent circuit model (ECM)-based SOC estimation algorithm using the extended Kalman filter (EKF). Experimental results indicate the robustness of the proposed work.
The Synthesis of Phosphaisocoumarins by Cu(I)-Catalyzed Intramolecular Cyclization of <i>o</i>-Ethynylphenylphosphonic Acid Monoesters (2003)

Cu(I)-catalyzed intramolecular cyclization of o-ethynylphenylphosphonic acid monoethyl esters was examined, and a new class of six-membered phosphorus heterocycles was formed with high regioselectivity and good yields. The present reaction is the first example of intramolecular addition of P-OH to alkynes, which provides a convenient way to synthesize novel phosphorus heterocycles having potential bioactivities.