gebhart/patrepeval huggingface dataset:
Coordinated placement and replacement for large-scale distributed caches (2003)

In a large-scale information system such as a digital library or the World Wide Web, a set of distributed caches can improve their effectiveness by coordinating their data placement decisions. Using simulation, we examine three practical cooperative placement algorithms, including one that is provably close to optimal, and we compare these algorithms to the optimal placement algorithm and several cooperative and non-cooperative replacement algorithms. We draw five conclusions from these experiments: (1) cooperative placement can significantly improve performance compared to local replacement algorithms, particularly when the size of individual caches is limited compared to the universe of objects; (2) although the Amortized Placement algorithm is only guaranteed to be within 14 times the optimal, in practice it seems to provide an excellent approximation of the optimal; (3) in a cooperative caching scenario, the GreedyDual local replacement algorithm performs much better than the other local replacement algorithms; (4) our Hierarchical GreedyDual replacement algorithm yields further improvements over the GreedyDual algorithm, especially when there are idle caches in the system; and (5) a key challenge to coordinated placement algorithms is generating good predictions of access patterns based on past accesses.
Different Effects of Cardioplegic Solution HTK during Single or Intermittent Administration (1984)

Since intermittent cardioplegic reperfusion during an ischemic period may reduce the ischemic stress of the heart at least by lowering myocardial temperature, we compared the post-ischemic recovery of the dog heart following cardioplegia and subsequent continuous ischemia of 1 X 300 minutes at 22 +/- 1 degree C (model 1) and following cardioplegia and subsequent 3 X 100 minutes of ischemia at 17 +/- 1 degree C with intermittent 4-minute cardioplegic reperfusion every 100 minutes (model 2). The parameters of post-ischemic recovery were the cardiac O2 consumption per beat at work (MVO2-E0): HR), the stability of cardiac rhythm, the left ventricular content of high-energy phosphates, and ultrastructure. Solution HTK with a magnesium concentration of 9 mM/L, in clinical use up to the beginning of 1984, resulted in a significantly better post-ischemic recovery in model 1, despite about 40% lesser ischemic stress in model 2. A reduction of Mg concentration from 9 to 4 mM/l, as in the HTK solution clinically tested since February 1984, did facilitate the post-ischemic recovery in model 1 as indicated by the stability of cardiac rhythm but led to a significant improvement of all parameters of recovery in model 2. Moreover, recovery in model 2 after reduced Mg was also clearly better than in model 1 corresponding to the lesser ischemic stress. The parameters myocardial O2 consumption (MVO2) and potassium loss during HTK perfusion containing 9 and 4 mM/l, respectively, gave indications of specific membrane labilizing effects of Mg in the cardioplegic solution HTK.
The effects of fillers and extenders on the cure properties of phenol–formaldehyde resin as determined by the application of thermal techniques (1991)

Abstract The techniques of dynamic mechanical thermal analysis (DMTA) and differential scanning calorimetry (DSC) were used to examine the effects of the addition of various fillers and extenders (clay, pecan shell flour, and wheat flour) on the curing mechanism of a phenolformaldehyde resol. The DMTA results indicated that the curing process was unaffected by any of the additives. The DSC thermograms showed a single exothermic peak that was not influenced to a great extent by the fillers or extenders. Comparison of viscosity measurements and gel time determinations showed slight differences in the physical properties of the uncured resins.
The stabilization of PVC against heat and light (1977)

The lecture provides a survey on the actual status of the heat and light stabilization of PVC with special emphasis on the mode of action of the stabilizers. In the first part a brief treatment of the most important facts of the thermal degradation of PVC are given, followed by a discussion of some proved specific functions of heat stabilizers by using organotin mercaptide as a typical example. A general concept differentiating preventive and curative stabilizer functions is proposed which seems to be applicable to all types of thermal stabilizers. The second part of the lecture deals with the problematics of light degradation and light stabilization. Some fundamental facts of the light degradation are briefly dealt with and provisions for an enhancement of the light stability are discussed, covering also the implication of the thermal stabilizers.
Aircraft Cabin Air Sampling Study: Part 1 of the Final Report (2011)

This is the second part of the report on aircraft cabin air quality prepared by Cranfield University for the Department for Transport. The study was set up in light of concerns about possible adverse impacts on the health and well-being of air crew resulting from exposure to substances in cabin air. Part 1 of the report describes in detail the methodology used in the study, summarises the results obtained and assesses cabin air quality against available exposure limits and the quality of air encountered in domestic settings. This second part comprises principally a record of the data obtained on individual flight sectors.
Immunoglobulin E–dependent Active Fatal Anaphylaxis in Mast Cell–deficient Mice (1998)

Mast cells have long been believed to be the central effector cells in the development of immunoglobulin (Ig)E-dependent anaphylaxis. In this study, we investigated the role of mast cells in IgE-dependent hapten-induced active fatal anaphylaxis using mast cell-deficient WBB6F1- W/Wv (W/Wv) and congenic normal (+/+) mice. Although a 5-min delay in shock signs and death were observed in W/Wv mice, 100% fatal reactions to penicillin V (Pen V) occurred in both +/+ and W/Wv mice. Administration of monoclonal anti-IL-4 antibody completely prevented the fatal reactions, and the effect of anti-IL-4 was associated with its suppressive activity on Pen V-specific serum levels of IgE, but not IgG. The platelet-activating factor (PAF) antagonist, BN 50739, completely prevented the fatal reactions in both strains of mice. Our kinetic study revealed, in contrast to no elevation of plasma histamine level in W/Wv mice, high levels of PAF in the circulation after challenge in both +/+ and W/Wv mice, albeit to a lesser degree in the latter case. These data indicate that cells other than mast cells are sufficient to induce an IgE-dependent active fatal anaphylaxis by elaborating PAF, which is the critical mediator for fatal murine anaphylaxis.
The gathering storm in high-density compact disks (1995)

The author describes how companies are taking sides over which kind of high-density compact disk to back in the coming war between Sony/Philips and Toshiba/Time Warner. The principles and performance of the competing designs are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
COPPER-SELENIDE AND COPPER-TELLURIDE COMPOSITES POWDERS SINTETIZED BY IONIC EXCHANGE (2014)

O. ARELLANO-TANORI, M. C. ACOSTA-ENRIQUEZ, R. OCHOA-LANDIN, R. INIGUEZ-PALOMARES, T. MENDIVIL-REYNOSO, M. FLORES-ACOSTA ,S. J. CASTILLO Departamento de Investigacion en Fisica, Universidad de Sonora, Apdo. Postal 5-088, CP. 83000, Hermosillo, Sonora, Mexico. Instituto Tecnologico y de Estudios Superiores de Monterrey, Campus Sonora Norte, Blvd. Enrique Mazon Lopez No. 965, C.P. 83000, Hermosillo, Son., Mexico Departamento de Fisica, Universidad de Sonora, Apdo. Postal 1626, CP. 83000 Hermosillo, Sonora, Mexico. Centro de Investigacion en Materiales Avanzados, Miguel de Cervantes 120, Complejo Industrial. CP 31109 Chihuahua, Chih., Mexico.
Assessment of Blood Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Patients With Non–Small Cell Lung Cancer With Use of a Next-Generation Sequencing Cancer Gene Panel (2019)

The findings suggest that established NCC-GP150 with an optimized gene panel size and algorithm is feasible for bTMB estimation, which may serve as a potential biomarker of clinical benefit in patients with NSCLC treated with anti-PD-1 and anti-PD-L1 agents.
Development and clinical application of surgical navigation system for laparoscopic hepatectomy (2015)

This paper describes a surgical navigation system for laparoscopic surgery and its application to laparoscopic hepatectomy. The proposed surgical navigation system presents virtual laparoscopic views using a 3D positional tracker and preoperative CT images. We use an electromagnetic tracker for obtaining positional information of a laparoscope and a forceps. The point-pair matching registration method is performed for aligning coordinate systems between the 3D positional tracker and the CT images. Virtual laparoscopic views corresponding to the laparoscope position are generated from the obtained positional information, the registration results, and the CT images using a volume rendering method. We performed surgical navigation using the proposed system during laparoscopic hepatectomy for fourteen cases. The proposed system could generate virtual laparoscopic views in synchronization with the laparoscope position during surgery.
Merged Fibers. Tailored Textiles for Tires (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMerged Fibers. Tailored Textiles for TiresF. J. Kovac, G. W. Rye, and M. F. DagueCite this: Ind. Eng. Chem. Prod. Res. Dev. 1966, 5, 1, 17–23Publication Date (Print):March 1, 1966Publication History Published online1 May 2002Published inissue 1 March 1966https://pubs.acs.org/doi/10.1021/i360017a003https://doi.org/10.1021/i360017a003research-articleACS PublicationsRequest reuse permissionsArticle Views67Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A new mask ROM cell programmed by through-hole using double polysilicon technology (1983)

A new through-hole programmed MASK ROM cell which is suitable for 1Mbit high speed MASK ROM with short turn around time in programming processes, and small cell size is descrived. The memory cell is implemented by NOR gate type which is most suitable for high speed MASK ROM. The new memory cell is successfully applied to 1Mbit MASK ROM with double polysilicon P-well C-MOS technology. A new structure and a new fabrication processes of the device element are also described.
Gametocytocidal and Sporontocidal Activity of Antimalarials against Plasmodium Berghei Anaka in Icr Mice and Anopheles Stephensi Mosquitoes (1992)

The gametocytocidal and sporontocidal activity of three 8-aminoquinolines (primaquine, WR-238605, and WR-242511), three dihydroacridine-diones (floxacrine, WR-250547, and WR-250548), a 1,4-naphthoquinone (menoctone), a synthetic aminoalcohol (halofantrine), and a guanide (WR-182393) was determined against a cloned line of Plasmodium berghei ANKA. Gametocytocidal activity was assessed by treating mice with a single intraperitoneal inoculation of a given compound (25 mg base drug/kg mouse body weight) four days after the mice were infected with P. berghei. Thin blood smears were made every other day, and the percent parasitemia and macrogametocyte and microgametocyte rates were determined. Floxacrine, menoctone, WR-242511, WR-250547, and WR-250548 effectively cleared sexual and asexual parasites from the peripheral circulation within six days of drug administration. Halofantrine, primaquine, WR-182393, and WR-238605 were ineffective at clearing P. berghei ANKA from circulating erythrocytes at the doses tested; however, mice survival time increased markedly with these compounds when compared with the controls. Significant numbers of macrogametocytes and microgametocytes were present throughout the duration of the infection in mice treated with halofantrine, primaquine, WR-182393, and WR-238605. Sporontocidal activity was evaluated by allowing Anopheles stephensi mosquitoes to feed on P. berghei-infected mice 90 min after treatment with a particular drug. Halofantrine and WR-182393 exhibited no sporontocidal activity, while floxacrine, menoctone, primaquine, WR-238605, WR-242511, WR-250547, and WR-250548 exhibited significant activity. Minimum effective doses (mg base drug/kg of mouse body weight) that prevented mosquitoes from developing sporozoite-infected salivary glands were 0.1563 mg/kg for WR-250547, 0.625 mg/kg for menoctone, 1.25 mg/kg for primaquine, 10 mg/kg for floxacrine, 10 mg/kg for WR-242511, 10 mg/kg for WR-250548, and 25 mg/kg for WR-238605.
Rugate filter sidelobe suppression using quintic and rugated quintic matching layers (1989)

Sine wave rugate index profiles may be superimposed on a slowly varying average index in such a way as to reduce sidelobes over broad spectral regions and at the same time maintain the strength of the stopband reflectance.
Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease (2008)

These data are the first to demonstrate that urinary MMPs may represent novel noninvasive biomarkers for use in the evaluation of patients with IBD.
Leveraging Social Networks To Motivate Individuals to Reduce their Ecological Footprints (2007)

What role can social networking Websites play in supporting large-scale group action and change? We are proposing to explore their use in supporting individual reduction in personal energy consumption. In this we summarize some existing uses of social networking on the Web and propose an approach that integrates feedback about ecological footprint data into existing social networking sites and Internet portal sites. Integrating such feedback into popular, commonly used sites allows frequent feedback about performance, while enabling the exploration motivational schemes that leverage group membership. We propose to compare different motivational schemes in three ways: reduction in C02 emission; lifestyle changes; and ongoing use by users who join the site (retention)
Defining genetic interaction (2008)

Sometimes mutations in two genes produce a phenotype that is surprising in light of each mutation's individual effects. This phenomenon, which defines genetic interaction, can reveal functional relationships between genes and pathways. For example, double mutants with surprisingly slow growth define synergistic interactions that can identify compensatory pathways or protein complexes. Recent studies have used four mathematically distinct definitions of genetic interaction (here termed Product, Additive, Log, and Min). Whether this choice holds practical consequences has not been clear, because the definitions yield identical results under some conditions. Here, we show that the choice among alternative definitions can have profound consequences. Although 52% of known synergistic genetic interactions in Saccharomyces cerevisiae were inferred according to the Min definition, we find that both Product and Log definitions (shown here to be practically equivalent) are better than Min for identifying functional relationships. Additionally, we show that the Additive and Log definitions, each commonly used in population genetics, lead to differing conclusions related to the selective advantages of sexual reproduction.
[Development of [18F]FRP-170 injection for imaging hypoxia by PET]. (2005)

A novel [18F]FRP-170 injection for imaging hypoxia by PET was developed for clinical use. The preparation was based on the simple on-column basic-hydrolysis and the whole procedure was automated by detecting He flow change for transferring and evaporating liquids. [18F]FRP-170 was prepared in around 15-20% decay-corrected radiochemical yield within 60 min and stable in saline for more than 6 hr. Radiochemical purity was over 99% and specific activity at EOS was 40-60 GBq/micromol. The radiation-absorbed dose to the whole body was estimated to be 1.0 mSv/185 MBq. The [18F]FRP-170 injection proved to be suitable for clinical use without acute toxicity or mutagenicity.
Chemical Vapor Deposition of Conformal, Functional, and Responsive Polymer Films (2009)

Chemical vapor deposition (CVD) polymerization utilizes the delivery of vapor-phase monomers to form chemically well-defined polymeric films directly on the surface of a substrate. CVD polymers are desirable as conformal surface modification layers exhibiting strong retention of organic functional groups, and, in some cases, are responsive to external stimuli. Traditional wet-chemical chain- and step-growth mechanisms guide the development of new heterogeneous CVD polymerization techniques. Commonality with inorganic CVD methods facilitates the fabrication of hybrid devices. CVD polymers bridge microfabrication technology with chemical, biological, and nanoparticle systems and assembly. Robust interfaces can be achieved through covalent grafting enabling high-resolution (60 nm) patterning, even on flexible substrates. Utilizing only low-energy input to drive selective chemistry, modest vacuum, and room-temperature substrates, CVD polymerization is compatible with thermally sensitive substrates, such as paper, textiles, and plastics. CVD methods are particularly valuable for insoluble and infusible films, including fluoropolymers, electrically conductive polymers, and controllably crosslinked networks and for the potential to reduce environmental, health, and safety impacts associated with solvents. Quantitative models aid the development of large-area and roll-to-roll CVD polymer reactors. Relevant background, fundamental principles, and selected applications are reviewed.
Ocular Complications (1982)

Ocular complications of diabetes in humans are reviewed briefly, and experimental models available for study of the complications are described. Potentially suitable models include not only diabetic animals, but also nondiabetic animals in which analogous lesions have been demonstrated. Many abnormalities of the lens, cornea, iris, and retina comparable to those of diabetes in humans may be observed in diabetic animals, although all abnormalities are not necessarily observed in every species. Retinal changes, in particular, may occur in diabetic animals of several species, but only in large animals (dogs, primates) have saccular capillary aneurysms been reproduced consistently, together with other retinal changes typical of diabetes in humans. A few examples of the uses of animal models are offered, and attention is called to a lack of animal models of proliferative diabetic retinopathy and of rubeosis iridis.
ANOVA and ANCOVA a GLM approach (2012)

Provides an in-depth treatment of ANOVA and ANCOVA techniques from a linear model perspective ANOVA and ANCOVA: A GLM Approach provides a contemporary look at the general linear model (GLM) approach to the analysis of variance (ANOVA) of one- and two-factor psychological experiments. With its organized and comprehensive presentation, the book successfully guides readers through conventional statistical concepts and how to interpret them in GLM terms, treating the main single- and multi-factor designs as they relate to ANOVA and ANCOVA. The book begins with a brief history of the separate dev
Parkin-induced mitophagy in the pathogenesis of Parkinson disease (2009)

Knockout of the ubiquitin ligase Parkin, the gene product of the Parkinson associated Park2, leads to loss of mitochondrial integrity and function in Drosophila melanogaster. Although Parkin is primarily cytosolic, we have found that Parkin is selectively recruited to dysfunctional mitochondria with low membrane potential and subsequently promotes their autophagy. Here we report that Parkin recruitment is voltage-dependent and independent of changes in ATP or pH. These findings suggest that Parkin promotes mitophagy of dysfunctional mitochondria following loss of mitochondrial membrane potential and implicates the targeted elimination of mitochondria in the pathogenesis of Parkinson disease.
A New Criterion to Determine the Start of Combustion in Diesel Engines (2005)

A new criterion for the determination of the start of combustion (SOC) from the diesel engine in-cylinder pressure diagram was developed. It is defined as the maximum of the third-order derivative of the cylinder pressure with respect to the crank angle. This criterion declares SOC more precisely than other previously published criteria based on pressure diagnostics. This fact was proven analytically and was discernable from the analysis of the experimental data. Besides its accuracy it is also robust enough to allow automatic evaluation of the SOC during processing of the pressure data for a large number of cycles. By applying the first law of thermodynamics analysis to the engine cylinder it was discovered that the third-order derivative of the in-cylinder pressure with respect to the crank angle is the most suitable criterion for determination of the SOC from the in-cylinder pressure diagram. Subsequently, the criterion was validated through experimental data analysis of the in-cylinder pressure diagrams for various engine speeds and loads. In order to evaluate the rate of heat release (ROHR), which formed the base for the experimental validation, in-cylinder pressure diagrams were processed with a computer code based on the first law of thermodynamics. The cylinder pressure was measured with an advanced piezoelectric sensor at the resolution 0.1 deg CA. Top dead center was determined with the capacitive top dead center sensor. Due to the analytic foundation of the developed method and its validation through highly accurate experimental data it can be concluded that new criterion is credible for the determination of the SOC.
Driving style recognition using fuzzy logic (2012)

Detection and classification of aggressive driving can be based on the use of physiological signals or biometric information like electrocardiogram, electro dermal activity, and respiration. This research proposes a driving performance inference system based on the signature of acceleration in the two dimensions and speed. Driving style can be categorized to: below normal, normal, aggressive, and very aggressive. One of the targets of this paper is to recognize the driving events that fall into each of these categories. Many of driving styles are a major cause of traffic crashes. Many of these styles can be detected with reasonable accuracy using driving performance. The main idea is to utilize the 2-axis accelerometer that is embedded in most of the GPS tracker devices that are used in vehicle tracking and fleet management to recognize the driving styles. This method can be utilized for vehicle active safety purpose. Fuzzy logic inference system is used in classification of the extracted feature to the predefined driving styles. the power of the Euclidean norm of longitudinal and lateral is used as input to the fuzzy inference system in addition to the speed. Classification of the driving style is real time and almost cost nothing.