gebhart/patrepeval huggingface dataset:
Carbon resistor gauges for measuring shock and detonation pressures. III. Revised calibration data and relationships (1995)

Abstract For many years, carbon resistors have formed the basis for measurement of shock and detonation pressures associated with condensed explosives. The gauge is fabricated by heat‐sealing the resistor into a plastic material such as polystyrene. When subjected to a strong shock wave, the resistance decreases, and the resulting increase in conductance is a function of the magnitude of the pressure. The present investigation was concerned with the experimental derivation of revised calibration equations, which was necessitated by the need to incorporate a terminating resistor into the gauge circuitry. The use of this resistor decreased the effect of standing waves and eliminated oscillatory ringing in the recorded signal. Typical records over a wide range of pressures are presented. An error analysis of the recorded data showed that the uncertainty in the measured pressure was of the same order of magnitude as the uncertainty in the interpretation of the recorded voltage from which the conductance was computed. An extensive discussion of the relevancy of the experimental data is presented, and the need for additional calibration experiments is stressed.
<i>PTGF-β</i> , a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-β signaling pathway (2000)

Identification and characterization of p53 target genes would lead to a better understanding of p53 functions and p53-mediated signaling pathways. Two putative p53 binding sites were identified in the promoter of a gene encoding PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member. Gel shift assay showed that p53 bound to both sites. Luciferase-coupled transactivation assay revealed that the gene promoter was activated in a p53 dose- as well as p53 binding site-dependent manner by wild-type p53 but not by several p53 mutants. The p53 binding and transactivation of the PTGF-beta promoter was enhanced by etoposide, a p53 activator, and was largely blocked by a dominant negative p53 mutant. Furthermore, expression of endogenous PTGF-beta was remarkably induced by etoposide in p53-positive, but not in p53-negative, cell lines. Finally, the conditioned medium collected from PTGF-beta-overexpressing cells, but not from the control cells, suppressed tumor cell growth. Growth suppression was not, however, seen in cells that lack functional TGF-beta receptors or Smad4, suggesting that PTGF-beta acts through the TGF-beta signaling pathway. Thus, PTGF-beta, a secretory protein, is a p53 target that could mediate p53-induced growth suppression in autocrinal as well as paracrinal fashions. The finding made a vertical connection between p53 and TGF-beta signaling pathways in controlling cell growth and implied a potential important role of p53 in inflammation regulation via PTGF-beta.
Assessing Handwriting Intervention Effectiveness in Elementary School Students: A Two-Group Controlled Study (2012)

This study examined the effectiveness of two approaches used in elementary schools to improve children's handwriting. Participants were 72 New York City public school students from the first and second grades. A nonequivalent pretest-posttest group design was used in which students engaged in handwriting activities using two approaches: intensive handwriting practice and visual-perceptual-motor activities. Handwriting speed, legibility, and visual-motor skills were examined after a 12-wk Handwriting Club using multivariate analysis of variance. The results showed that students in the intensive handwriting practice group demonstrated significant improvements in handwriting legibility compared with students in the visual-perceptual-motor activity group. No significant effects in handwriting speed and visual-motor skills were found between the students in intensive handwriting practice group and the students in visual-perceptual-motor activities group. The Handwriting Club model is a natural intervention that fits easily into existing school curriculums and can be an effective short-term intervention (response to intervention Tier II).
The effect of salicylate on glycosuria, blood glucose and liver glycogen of the alloxan-diabetic rat (1952)

Large doses of salicylates have been reported to prevent diabetic glycosuria in man and the drug was used in the treatment of diabetes during the latter part of the last century (Gross & Greenberg, 1948).
요추추간판탈출증에 대한 약침의 시술깊이에 따른 효과 차이 (2012)

Objectives
The aim of this study is to investigate the difference of effectiveness according to Pharmacopuncture treatment depth on lumbar spinal...
Structure of Glucoamylase from Saccharomycopsis fibuligera at 1.7 Å Resolution (1998)

The yeast Saccharomycopsis fibuligera produces a glucoamylase which belongs to sequence family 15 of glycosyl hydrolases. The structure of the non-glycosyl­ated recombinant enzyme has been determined by molecular replacement and refined against 1.7 Å resolution synchrotron data to an R factor of 14.6%. This is the first report of the three-dimensional structure of a yeast family 15 glucoamylase. The refinement from the initial molecular-replacement model was not straightforward. It involved the use of an unrestrained automated refinement procedure (uARP) in combination with the maximum-likelihood refinement program REFMAC. The enzyme consists of 492 amino-acid residues and has 14 α-helices, 12 of which form an (α/α)6 barrel. It contains a single catalytic domain but no starch-binding domain. The fold of the molecule and the active site are compared to the known structure of the catalytic domain of a fungal family 15 glucoamylase and are shown to be closely similar. The active- and specificity-site residues are especially highly conserved. The model of the acarbose inhibitor from the analysis of the fungal enzyme fits tightly into the present structure. The active-site topology is a pocket and hydrolysis proceeds with inversion of the configuration at the anomeric carbon. The enzyme acts as an exo-glycosyl hydrolase. There is a Tris [2-amino-2-(hydroxymethyl)-1,3-propanediol] molecule acting as an inhibitor in the active-site pocket.
Plasminogen Activator Inhibitor‐1: Physiologic Role, Regulation, and the Influence of Common Pharmacologic Agents (2002)

Plasminogen activator inhibitor-1 (PAI-1) is the major inhibitor of endogenous thrombolysis, thereby promoting thrombosis. PAI-1 is also a primary contributor to the development and recurrence of acute myocardial infarction. The renin angiotensin system, hypertriglyceridemia, hyperglycemia and hyperinsulinemia, and estrogen all influence the fibrinolytic system and PAI-1 in particular. Available data strongly suggest that angiotensin-converting enzyme (ACE) inhibitors and hormone replacement therapy with estrogen beneficially reduce PAI-1 production. Metformin, an agent commonly used for non-insulin-dependent diabetes mellitus (NIDDM), appears to favorably decrease PAI-1 production in NIDDM patients but not nondiabetic patients. Among the cholesterol-lowering statins, clinical literature evaluating pravastatin provides the most compelling data to support this agent's favorable effect on PAI-1. Other available statins either have not displayed an effect on PAI-1 or do not have clear data to conclusively define their effects on the fibrinolytic system.
PARASITIC CAPACITANCE CANCELLATION OF INTEGRATED CM FILTER USING BI-DIRECTIONAL COUPLING GROUND TECHNIQUE (2013)

This paper introduces a method for canceling the parasitic capacitance of integrated common mode (CM) fllter by optimizing the layout of ground winding. Firstly, the CM fllter with positive or negative coupling between the ground and inductor winding is researched, respectively. Then, the two coupling polarizes are combined to form the bi-directional coupling, simulation and measured results show bi-directional coupling ground can efiectively improve the high frequency (HF) flltering performance. The equivalent circuits are given to demonstrate the cancellation mechanism, and modelling is derived for the design of ground winding. To further validate the application of proposed technique, CM noise and input/output signals for PFC (Power Factor Correction) converter with bi-directional coupling ground CM fllter are simulated. The noise spectrums show conductive interference at high frequencies is efiectively suppressed and meets the required electromagnetic interference (EMI) standard.
DERMATITIS CAUSED BY ETHYL GASOLINE (1933)

The patient was a man, aged 30, married, with no children. The past history was essentially without significance, except that part which concerned the dermatitis. Three days before I saw him, an urticarial eruption developed, which involved the entire body, with edema of the lips, eyelids, hands and feet. There were pain in the joints, headache, chills and nausea, with a slight rise in temperature. The patient had been in contact with ethyl gasoline, which he was testing, about six hours before the eruption developed. He complained of considerable itching in the erupted areas. The first examination revealed a generalized urticarial eruption. Some of the wheals were about the size of a half-dollar; others varied from 2 to 3 cm. in diameter. They were most pronounced on the arms, forearms and back. Interspersed between the wheals was an erythematous eruption, circinate in type. A detailed history revealed that the patient
An Object-Oriented Traffic Simulation with IVHS Applications (1991)

<div class="htmlview paragraph">Many traffic simulation models have been developed over the years; however, most existing models are not well-suited for evaluating Intelligent Vehicle/Highway Systems (IVHS) concepts. This paper describes a new model, the Vehicular Traffic Analysis Capability (VTAC), specifically designed to model Advanced Traffic Management and Advanced Traveler Information systems. The model was developed using object-oriented analysis and design principles, and implemented in a relatively new, object-oriented, simulation language. VTAC is believed to be the first traffic model developed using the object-oriented paradigm. The principles used in the new model's design and the preliminary results obtained to-date are described. The model can currently model arterial networks, and sufficient progress has been made to demonstrate the utility of the object-oriented approach to traffic modeling.</div>
Insight into Residues Critical for Antithrombin Function from an Expanded Database of Sequences That Includes Frog, Turtle and Ostrich Antithrombins (2002)

This article has no abstract.
Discovery of a Novel Series of Inhibitors of Lymphoid Tyrosine Phosphatase with Activity in Human T Cells (2011)

The lymphoid tyrosine phosphatase LYP, encoded by the PTPN22 gene, is a critical regulator of signaling in T cells and recently emerged as a candidate target for therapy of autoimmune diseases. Here, by library screening, we identified a series of noncompetitive inhibitors of LYP that showed activity in primary T cells. Kinetic analysis confirmed that binding of the compounds to the phosphatase is nonmutually exclusive with respect to a known bidentate competitive inhibitor. The mechanism of action of the lead inhibitor compound 4e was studied by a combination of hydrogen/deuterium-exchange mass spectrometry and molecular modeling. The results suggest that the inhibitor interacts critically with a hydrophobic patch located outside the active site of the phosphatase. Targeting of secondary allosteric sites is viewed as a promising yet unexplored approach to develop pharmacological inhibitors of protein tyrosine phosphatases. Our novel scaffold could be a starting point to attempt development of "nonactive site" anti-LYP pharmacological agents.
A system and methodologies for absolute quantum efficiency measurements from the vacuum ultraviolet through the near infrared (2011)

In this paper we present our system design and methodology for making absolute quantum efficiency (QE) measurements through the vacuum ultraviolet (VUV) and verify the system with delta-doped silicon CCDs. Delta-doped detectors provide an excellent platform to validate measurements through the VUV due to their enhanced UV response. The requirements for measuring QE through the VUV are more strenuous than measurements in the near UV and necessitate, among other things, the use of a vacuum monochromator, good dewar chamber vacuum to prevent on-chip condensation, and more stringent handling requirements.
Advances in Ophthalmology Vol 14 (1964)

This annual review consists of three papers. The first is an account of "hemorrhagic glaucoma" by Sibylle Krüger of Basel. In an attempt to retain this irrational term the author restricts its meaning to that glaucoma which follows central retinal vein thrombosis and secondary rubeosis iridis. The account is a detailed one, but since pathogenesis is unknown and treatment is notably ineffective the overall result is not impressive. The second paper is an account of the experimental and spontaneous retinal degenerations of animals—a useful summary in itself. Curiously, the effect of glutamate poisoning on the retina is overlooked. The third review, and the last 194 pages of the book, deals with the literature on the retina from 1952 to 1959. The exhaustive nature of this review is impressive. The cutoff date four years before publication leaves many problems inadequately discussed in the light of present knowledge.
Polynorbornene with Cross-Linkable Side Chains via Ring-Opening Metathesis Polymerization (2000)

The ring-opening metathesis polymerization (ROMP) of 5-(methyl methacryloyl isocyanate)bicyclo[2.2.1]hept-2-ene [i.e., norbornene containing methacryloyl isocyanate (NBMMAI)] having cyclic olefin and terminal double bond was investigated in order to produce novel polymers with cross-linkable side chains under ligand exchange with MMA by using {RuCl2(CHPh)[P(C6H11)3]2} (II) as catalyst. Results of infrared spectra, 1H NMR, and 13C NMR showed that poly(NBMMAI) contains polynorbornene backbone ring structure and methacryloyl side chains. The 1H NMR spectrum of poly(NBMMAI) showed new vinyl protons as a broad signal between 5.15 and 5.37 ppm in the ratio of 0.4 and 2.8, corresponding to the vinyl protons of the cis and trans double bond of the ring-opened polymer, respectively. Gel formation was still observed in the polymerization of NBMMAI using ruthenium catalyst II with 20 mol % p-methoxyphenol (MEHQ). An increase in bulkiness of the ligand reduced the cross metathesis reaction and led to reduced activity for the catalyst. Increasing the ratio of monomer concentration [M] to catalyst [cat] resulted in the formation of higher molecular weight polymers and polymer yield. The incorporation of poly(NBMMAI) into poly(methyl methacylate) (polyMMA) to produce AB cross-linked materials was accomplished. These cross-linked materials had higher thermal stability and solvent resistance than pure polyMMA.
Photonic memory switch: monolithic integration of a voltage-controlled bistable laser diode and an optical gate (1992)

An electrically controlled photonic memory switch which monolithically integrates a voltage-controlled bistable laser diode and an optical gate on an InP substrate is fabricated. Time-division optical signal processing such as pulsewidth conversion and a pulse delay control is successfully demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Central and systemic haemodynamic effects of terlipressin in portal hypertensive patients (2000)

Terlipressin significantly attenuates the hyperdynamic circulation in portal hypertensive patients without a further contraction of the central and arterial blood volume. The systemic haemodynamic response to terlipressin is moreover associated with the decrease in portal pressure. Terlipressin may therefore have potentially beneficial effects on the hyperdynamic circulation in cirrhosis in addition to its effects on portal pressure.
Using out-of-domain data to improve in-domain language models (1997)

Standard statistical language modeling techniques suffer from sparse data problems when applied to real tasks in speech recognition, where large amounts of domain-dependent text are not available. We investigate new approaches to improve sparse application-specific language models by combining domain dependent and out-of-domain data, including a back-off scheme that effectively leads to context-dependent multiple interpolation weights, and a likelihood-based similarity weighting scheme to discriminatively use data to train a task-specific language model. Experiments with both approaches on a spontaneous speech recognition task (switchboard), lead to reduced word error rate over a domain-specific n-gram language model, giving a larger gain than that obtained with previous brute-force data combination approaches.
Highly Luminescent ZnO Nanocrystals Stabilized by Ionic‐Liquid Components (2006)

A new approach to stabilization of ZnO nanocrystals by ionic-liquid components, which endow the nanocrystals with high thermal stability and good fluidity, is demonstrated. The ionic-liquid/ZnO composites exhibit tunable photoluminescence (see picture) with a high quantum yield.
A 120dB CMOS Imager with a Light Adaptive System and Digital Outputs (2006)

A novel CMOS image sensor architecture implementing a light adaptive system with a high dynamic range is presented. This new differential architecture of the column amplifier enables a good precision and a reduced column FPN. A 128times128 pixel array has been designed in 0.35mum, 3.3V standard technology. The pixel measures 15mumtimes15mum and the fill factor is about 16%. The dynamic range expected is up to 120dB with a frame rate up to 30 images per second
Analog Array Processing Of PtSi Focal Plane Imagery (1985)

A novel, fully programmable, parallel-architecture, analog array processor will be described which can meet the high throughput requirements of real-time image processing systems. This architecture, when implemented with charge coupled device technology, can be interfaced directly with a PtSi sensor array to provide the capability of fabricating a compact, high-throughput module which has application in a wide variety of areas in tracking, guidance and position sensing.
Synthesis and Characterization of Poly(arylene ether)s Containing Benzoxazole Pendants from Novel Aromatic Difluoride Monomer (2000)

A study was done on the synthesis of new poly(arylene ether)s and poly(arylenesulfide) with rigid benzoxazole pendants using nucleophilic aromatic substitution reaction. As a new aromatic monomer, 1,4-bis(2-benzox-azolyl)-2,5-difluorobenzene [I] w as synthesized in three steps starting from 1,4-dibromo-2,5-difluorobenzene. A model reaction of difluoro monomer [I] with two equivalents of m-cresol or thiophenol in a typical ether con-densation reaction conditions gave very high yields ( > 93%) of the desired disubstituted product, suggesting the feasibility of polymer formation in these reaction system. Monomer[I] was polymerized with bisphenols and bisbenzenethiol in NMP using K2CO3 as base. The molecular weight of the resulting polymers, however,seemed relatively low according to their solution viscosity values ( ηinh = 0.15-0.29 dL/g). The poly(arylene ether)s were soluble in several common organic solvents including chloroform, pyridine and N,N'-dimethylfor-mamide. The poly(arylene sulfide) was, however, ony soluble in strong acids like sulfuric acid and trifluoro-acetic acid. The glass transition temperatures were found to be 175-215 These polymers were stable up to 380-420 in both nitrogen and air, as determined by the temperature that a significant weight loss began to appear on TGA.
Faecal chymotrypsin assay in tropical and alcoholic chronic pancreatitis. (1991)

Faecal chymotrypsin (FCT) levels were estimated in a group of patients with tropical chronic pancreatitis (TCP) and compared with patients with alcoholic chronic pancreatitis (ACP), 'gastrointestinal' controls and 'healthy' subjects. Exocrine pancreatic insufficiency as assessed by low faecal chymotrypsin levels (less than 5.8 mu/g) were present in 85.7 per cent of TPC and 84.6 per cent of ACP patients. Mean FCT levels as well as the distribution of FCT values were similar in TCP and ACP patients and significantly lower than the two control groups (P less than 0.001). There was also no difference with respect to mean FCT levels between subgroups of TCP patients with and without diabetes and those with and without calcification. Faecal chymotrypsin assay is a simple test for diagnosis of chronic pancreatitis in gastroenterological centres in tropical countries.
Real-Time Illegal Parking Detection in Outdoor Environments Using 1-D Transformation (2009)

With decreasing costs of high-quality surveillance systems, human activity detection and tracking has become increasingly practical. Accordingly, automated systems have been designed for numerous detection tasks, but the task of detecting illegally parked vehicles has been left largely to the human operators of surveillance systems. We propose a methodology for detecting this event in real time by applying a novel image projection that reduces the dimensionality of the data and, thus, reduces the computational complexity of the segmentation and tracking processes. After event detection, we invert the transformation to recover the original appearance of the vehicle and to allow for further processing that may require 2-D data. We evaluate the performance of our algorithm using the i-LIDS vehicle detection challenge datasets as well as videos we have taken ourselves. These videos test the algorithm in a variety of outdoor conditions, including nighttime video and instances of sudden changes in weather.
Peg-in-Hole assembly using Impedance Control with a 6 DOF Robot (1996)

To gain insight in problems of industrial assembly operations, an anthropomorphic robot equipped with a vision system was used to insert differently shaped pegs into corresponding holes of a plastic ball. Spatial impedance control was used, to properly deal with the interaction between robot and environment and to elegantly chose the impedance of the robot. Simulations gave insight into the behavior of the manipulator during free motion and during contact. Experimental results complied with simulations, but contact forces appeared to be higher than the simulated ones.
Transplanter Modification and Survival of Transplants under No-tillage Conditions1 (1973)

Abstract A tractor-drawn transplanting machine was substantially modified for operation in chemically-killed sods. The modifications included using a rolling coulter, double-disc furrow opener, narrow press wheels and considerable ballast weight. The use of this transplanter makes possible plot and field trials with transplanted-type crops under “no-tillage“ culture. Sod plots were treated with one or more applications of Paraquat herbicide to kill the vegetation. Tobacco, tomato and pepper plants were established in conventional and no-tillage plots. Plant survivability was generally more variable using no-tillage, but the significant differences were attributed to non-machine cultural problems. The no-till transplanter operátion was adequate under all conditions encountered.