gebhart/patrepeval huggingface dataset:
Exploiting hierarchy in parallel computer networks to optimize collective operation performance (2000)

The ecient implementation of collective communication operations has received much attention. Initial eorts modeled network communication and produced \\optimal&quot; trees based on those models. However, the models used by these initial eorts assumed equal point-to-point latencies between any two processes. This assumption is violated in heterogeneous systems such as clusters of SMPs and wide-area \\computational grids&quot;, and as a result, collective operations that utilize the trees generated by these models perform suboptimally. In response, more recent work has focused on creating topology-aware trees for collective operations that minimize communication across slower channels (e.g., a wide-area network). While these efforts have signicant communication benets, they all limit their view of the network to only two layers. We present a strategy based upon a multilayer view of the network. By creating multilevel topology trees we take advantage of communication cost dierences at every lev...
Maternal Endotoxemia Results in Obesity and Insulin Resistance in Adult Male Offspring* (2001)

Events in utero appear to be important factors contributing to the development of somatic disorders at adult age. The aim of this study was to examine whether maternal immune challenge would be followed at adult age by metabolic and endocrine abnormalities in the offspring. Pregnant rats were given injections of either endotoxin (Escherichia coli lipopolysaccharide; 0.79 mg/kg, ip) or vehicle on days 8, 10, and 12 of gestation. Adult male offspring to lipopolysaccharide-exposed dams were heavier than controls (P < 0.05) and showed increased adipose tissue weights (P < 0.05), elevated food intake (P < 0.05), and increased circulating leptin (P < 0.01). The effect of insulin on glucose uptake was reduced, as measured by an euglycemic hyperinsulinemic clamp technique (P < 0.05). Serum levels of 17beta-estradiol and progesterone were elevated (P < 0.01 and P < 0.05, respectively). Baseline levels of corticosterone were normal, but the corticosterone response to stress was attenuated (P < 0.05), and hippocampal glucocorticoid receptor protein was up-regulated (P < 0.05). Female offspring were uninfluenced, except for increased testosterone levels (P < 0.05), increased baseline corticosterone levels (P < 0.05), and enlargement of heart and adrenals (P < 0.05). The results indicate that maternal endotoxemia leads to obesity, insulin resistance, and high serum levels of leptin in the adult male offspring. This study reports a novel animal model of obesity with features of the metabolic syndrome.
Chemical Library and Structure–Activity Relationships of 11-Demethyl-12-oxo Calanolide A Analogues as Anti-HIV-1 Agents (2008)

(+)-Calanolide A ( 1) as a natural product was previously found as an inhibitor of HIV-1 reverse transcriptase. In our further investigation of its template, racemic 11-demethyl-12-oxo calanolide A ( 15), which had two fewer chiral carbon centers at the C-11 and C-12 positions than (+)-calanolide A, had a comparably inhibitory activity and better therapeutic index (EC 50 = 0.11 microM, TI = 818) against HIV-1 in vitro. A library based on its structural core was then designed and synthesized with introduction of nine diversity points in this article. The evaluations of anti-HIV-1 activity in vitro concluded their structure-activity relationships (SARs). A novel compound (10-bromomethyl-11-demethyl-12-oxo calanolide A, 123) was identified to have much higher inhibitory potency and therapeutic index (EC 50 = 2.85 nM, TI > 10,526) than those of the class compound against HIV-1. This finding provided a very important clue that modifications of the C ring at the C-10 position may be conducted to obtain drug candidates with better activity against HIV-1.
A ring-type device for the noninvasive measurement of arterial blood pressure (2004)

A ring-type device based on photoplethysmogram (PPG) and electrocardiogram (ECG) can be worn by a person at all times for the noninvasive and continuous measurement of arterial blood pressure (BP). A motion-free PPG is very important in order to obtain accurate BP value. In this paper, the optimal finger-ring and circuit designs for stable PPG signal detection and accurate R-wave detection are presented. A series of comparative experiments are conducted on 10 subjects using various ring sensors with different configurations. The experimental results show that the convex-type ring sensor, in which light emitting diode (LED) and infrared (IR) detector are placed at the palm side, and separated by a distance of around 1cm, is the optimal choice for ring-type BP measurement.
Talker-Recognition Procedure Based on Analysis of Variance (1964)

This paper describes a talker-recognition procedure that selects a small subset of features from a much larger body of data and bases recognition on this subset. The subset is chosen as those features having small variation between utterances of a given talker as compared to the variation among utterances of different talkers. This procedure is applied to materials consisting of quantized spectrographic information from a group of 10 talkers uttering 10 different words 7 times each. Features are formed as the average of the speech energy over certain rectangular areas on the spectrograms. Results are computed as a function of the number of features used and as a function of the size of the areas used to form the features. Although this paper treats only talker recognition, the recognition procedure is general and can be applied to other problems where it is desirable to use a simple method to select a few important features from a much larger set that can number several thousands.
Structural Properties of Antireflection Coatings (2007)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text T. V. Amotchkina, A. V. Tikhonravov, M. K. Trubetskov, and S. A. Yanshin, "Structural Properties of Antireflection Coatings," in Optical Interference Coatings, OSA Technical Digest (CD) (Optica Publishing Group, 2007), paper WB5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Airframe noise studies on wings with deployed high-lift devices (1998)

Employment of quiet high-bypass-ratio engines to propel current and future very large has caused airframe noise to become a significant contributor to the overall radiated noise from an aircraft in landing approach. This has brought about a worldwide resurgence of airframe noise studies, to try and understand the aeroacoustics of, and to ultimately control the aerodynamically caused noise from aircraft components deployed during the final approach leg, such as landing gears and high-lift devices (HLD) on wings. In view of European aviation industry to design and build a large commercial aeroplane, a substantial and dedicated German National Research Project was initiated, culminating in a series of model- und full-scale wind tunnel experiments on HLD. This paper discusses initial results from HLD-studies in the DLR Aeroacoustics Wind Tunnel Brauschweig (AWB) where an acoustic mirror was employed on a 1/10 scale-model wing section to identify the aeroacoustic source mechanisms of slat-noise and flap side-edge noise. Tests were performed for different flow velocities and wing angles-of-attack, indicating that the slat tracks constitute sources of excessive flow noise. Moreover, both slat-noise and flap side-edge noise, respectively, were found to each be a result of specific combinations of different unsteady-aerodynamics mechanisms. Several, though still preliminary noise reduction techniques were tested, showing nevertheless significant promise to enable containment of otherwise excessive slat-noise and flap side-edge noise, such techniques being quite feasible for future full-scale application.
Intra- and Interspecies Signaling between <i>Streptococcus salivarius</i> and <i>Streptococcus pyogenes</i> Mediated by SalA and SalA1 Lantibiotic Peptides (2001)

Streptococcus salivarius 20P3 produces a 22-amino-acid residue lantibiotic, designated salivaricin A (SalA), that inhibits the growth of a range of streptococci, including all strains of Streptococcus pyogenes. Lantibiotic production is associated with the sal genetic locus comprising salA, the lantibiotic structural gene; salBCTX genes encoding peptide modification and export machinery proteins; and salYKR genes encoding a putative immunity protein and two-component sensor-regulator system. Insertional inactivation of salB in S. salivarius 20P3 resulted in abrogation of SalA peptide production, of immunity to SalA, and of salA transcription. Addition of exogenous SalA peptide to salB mutant cultures induced dose-dependent expression of salA mRNA (0.2 kb), demonstrating that SalA production was normally autoregulated. Inactivation of salR encoding the response regulator of the SalKR two-component system led to reduced production of, and immunity to, SalA. The sal genetic locus was also present in S. pyogenes SF370 (M type 1), but because of a deletion across the salBCT genes, the corresponding lantibiotic peptide, designated SalA1, was not produced. However, in S. pyogenes T11 (M type 4) the sal locus gene complement was apparently complete, and active SalA1 peptide was synthesized. Exogenously added SalA1 peptide from S. pyogenes T11 induced salA1 transcription in S. pyogenes SF370 and in an isogenic S. pyogenes T11 salB mutant and salA transcription in S. salivarius 20P3 salB. Thus, SalA and SalA1 are examples of streptococcal lantibiotics whose production is autoregulated. These peptides act as intra- and interspecies signaling molecules, modulating lantibiotic production and possibly influencing streptococcal population ecology in the oral cavity.
A Comparative Investigation of the Li Insertion Properties of the Novel Fluorophosphate Phases, NaVPO[sub 4]F and LiVPO[sub 4]F (2004)

The electroactive vanadium fluorophosphate compounds, and have been successfully synthesized using a range of preparative strategies, including solid state (ceramic), hydrothermal, and ion exchange methods. In all preparative approaches a carbothermally synthesized vanadium(III) phosphate, was used as a suitable intermediate phase. The is found to crystallize with a tetragonal symmetry (space group and is structurally related to the previously reported sodium aluminum fluorophosphate phase, Low rate testing of the solid state and hydrothermally prepared samples reveals a reversible specific capacity in the range 97-110 mAh/g, and this performance is coupled to exceptional insertion stability at both 23 and 60°C. The voltage profile response during extraction/insertion for the system is consistent with the alkali ions occupying two energetically nonequivalent crystallographic sites within the fluorophosphate framework. The phase crystallizes with a triclinic structure (space group and is found to be isostructural with the known mineral, Tavorite, High-resolution electrochemical measurements reveal a structured voltage response for the lithium extraction process consistent with the lithium ions occupying two crystallographic positions. For the solid-state synthesized sample, the discharge process suggests a two-phase insertion mechanism coupled to phase nucleation behavior. Elevated temperature testing indicates that the lithium extraction process may yield the novel delithiated phase, The reversible specific capacities for the solid-state and ion-exchanged materials are found to approach 120 mAh/g and when coupled to an average discharge voltage in the range 4.10-4.20 V vs. Li, we believe this insertion system may offer some favorable characteristics for commercial application. © 2004 The Electrochemical Society. All rights reserved.
Structure of the Carbohydrate Units of IgA1 Immunoglobulin (1974)

the structure of the two asparagine-linked oligosaccharide units of an IgAl myeloma protein was defined.In this paper we present data which establish the structure and linkage points of the five Oglycosidically linked oligosaccharide units found on the CX~ subtype heavy chain to be as shown below.
Lactoferrin in human amniotic fluid (1989)

The concentration of human lactoferrin (LF) was measured by radioimmunoassay or non-competitive avidin--biotin assay in amniotic fluid, cord blood and in the decidua, trophoblast, fetal membranes and umbilical cord. Amniotic fluid was obtained by amniocentesis, and cord blood and tissue samples were taken after delivery or elective Caesarean section. No detectable concentration of LF was found in amniotic fluid before week 20 of pregnancy. A significant increase in the LF concentration was observed around week 30 and it remained high until term. In cord blood, an undetectable or low concentration of LF was measured. In tissue specimens the amount of LF was highest in the decidua (9-95 micrograms/g), a moderate concentration was assayed in the amniotic (2-37 micrograms/) and chorion (2-26 micrograms/g) membrane and in the trophoblast (5-35 micrograms/g). In the umbilical cord, the concentration was less than 1 microgram/g. These results suggest a decidual origin of LF. The role of LF during pregnancy is discussed.
Performance of idle mode mobility state detection schemes in Evolved UTRAN (2010)

In this paper we study the performance of idle mode mobility state detection schemes targeted for 3rd Generation Partnership Project (3GPP) Evolved UTRAN. The purpose is to compare the mobility state detection scheme specified in 3GPP Release 8 and a dual trigger scheme for 3GPP Release 9 using different User Equipment (UE) velocity conditions and cell reselection triggering sensitivity levels. A single set of cell reselection parameters may not be optimal throughout the E-UTRAN velocity range, thus both schemes provide in a way a means of using UE velocity dependent cell reselection parameters. According to the results, both schemes provide gain over a single set of cell reselection parameters. Dual trigger provides gain over Release 8 mobility state detection scheme in terms of time spent in the best cell and downlink SINR. However, this comes with a small increase in power consumption due to increased amount of cell reselections per UE.
Cell Wall Anchoring of the 37-Kilodalton Oncofetal Antigen by <i>Lactobacillus plantarum</i> for Mucosal Cancer Vaccine Delivery (2010)

The 37-kDa oncofetal antigen (OFA), a tumor immunogen expressed on all mammalian cancers examined to date, was secreted and anchored to the cell wall of Lactobacillus plantarum using homologous signal peptides and LPxTG anchors. Orally administered L. plantarum expressing anchored OFA induced a specific immune response against OFA in mice.
Delivery of CRISPR/Cas9 by Novel Strategies for Gene Therapy (2018)

Precise editing of the genome of a living body is a goal pursued by scientists in many fields. In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas (CRISPR-associated) genome-editing systems have become a revolutionary toolbox for gene editing across various species. However, the low transfection efficiency of the CRISPR/Cas9 system to mammalian cells in vitro and in vivo is a big obstacle hindering wide and deep application. In this review, recently developed delivery strategies for various CRISPR/Cas9 formulations and their applications in treating gene-related diseases are briefly summarized. This review should inspire others to explore more efficient strategies for CRISPR system delivery and gene therapy.
Essentiality of Ribosomal and Transcription Antitermination Proteins Analyzed by Systematic Gene Replacement in <i>Escherichia coli</i> (2007)

We describe here details of the method we used to identify and distinguish essential from nonessential genes on the bacterial Escherichia coli chromosome. Three key features characterize our method: high-efficiency recombination, precise replacement of just the open reading frame of a chromosomal gene, and the presence of naturally occurring duplications within the bacterial genome. We targeted genes encoding functions critical for processes of transcription and translation. Proteins from three complexes were evaluated to determine if they were essential to the cell by deleting their individual genes. The transcription elongation Nus proteins and termination factor Rho, which are involved in rRNA antitermination, the ribosomal proteins of the small 30S ribosome subunit, and minor ribosome-associated proteins were analyzed. It was concluded that four of the five bacterial transcription antitermination proteins are essential, while all four of the minor ribosome-associated proteins examined (RMF, SRA, YfiA, and YhbH), unlike most ribosomal proteins, are dispensable. Interestingly, although most 30S ribosomal proteins were essential, the knockouts of six ribosomal protein genes, rpsF (S6), rpsI (S9), rpsM (S13), rpsO (S15), rpsQ (S17), and rpsT (S20), were viable.
Band diagram of the AlF3∕SiO2∕Si system (2005)

The material system aluminum fluoride-silicon oxide-silicon (AlF3∕SiO2∕Si) can localize a high density of fixed negative charges in fluorine (F) vacancies within AlF3, serving as a source for a strong drift field. This assignment is corroborated by a determination of the stoichiometry with Rutherford backscattering techniques and the transient response of the negatively charged defects with deep level transient spectroscopy. From the density-functional calculations of stoichiometric and understoichiometric AlF3, we deduce a microscopic picture where the energetic eigenstates of the the singly and doubly occupied F vacancies surround the Fermi energy. The lineup of the band edges of the system AlF3∕SiO2∕Si is determined by self-consistent electrostatic calculations including local charges, resulting in excellent agreement with the energetics deduced from the transient response of the charged defects.
Investigation of prospects for forecasting non-linear time series by example of drilling oil and gas wells (2018)

Discrete time series or mappings are proposed for describing the dynamics of a nonlinear system. The article considers the problems of forecasting the dynamics of the system from the time series generated by it. In particular, the commercial rate of drilling oil and gas wells can be considered as a series where each next value depends on the previous one. The main parameter here is the technical drilling speed. With the aim of eliminating the measurement error and presenting the commercial speed of the object to the current with a good accuracy, future or any of the elapsed time points, the use of the Kalman filter is suggested. For the transition from a deterministic model to a probabilistic one, the use of ensemble modeling is suggested. Ensemble systems can provide a wide range of visual output, which helps the user to evaluate the measure of confidence in the model. In particular, the availability of information on the estimated calendar duration of the construction of oil and gas wells will allow drilling companies to optimize production planning by rationalizing the approach to loading drilling rigs, which ultimately leads to maximization of profit and an increase of their competitiveness.
Multiphoton-Injected Plasmas in InSb (1969)

Electron-hole plasmas injected in InSb by irradiation with an intense C${\mathrm{O}}_{2}$ laser beam are studied. These plasmas result from multiphoton production of electron-hole pairs in pure InSb samples. The density, homogeneity, recombination radiation, and conductivity of these injected plasmas were observed at 77 and 4.2\ifmmode^\circ\else\textdegree\fi{}K in external magnetic fields from 0 to 55 kOe. It is found that homogeneous plasma densities of ${10}^{15}$ ${\mathrm{cm}}^{\ensuremath{-}3}$ can be produced over a 1-mm cube. Possible mechanisms for plasma lifetimes are discussed. Interesting properties and applications of the multiphoton-injected plasma are suggested.
Gluing & clamping : a woodworker's handbook (1986)

This guide contains 27 projects to create decorative pieces of furniture, using techniques such as sponging, wood graining, faux inlay, lacquering, stencilling and distressed effects. Projects include an Oriental lacquer table, a contemporary folk art cabinet, and a springtime garden bench.
Research in a high-fidelity acceleration environment (tactical aircraft) (2003)

The lightweight cockpit (LWC) installed in the human centrifuge at NADC, one approach to creating an acceleration environment similar to that of tactical aircraft, is described. This centrifuge is capable of very high onset and sustained accelerations. A pilot in the human centrifuge flies an aircraft simulation to maintain a target aircraft inside the gun pipper of a head-up display. The pilot is in complete control of the centrifuge through the simulation, and if the target tracking is accomplished successfully, the centrifuge will produce an acceleration profile that matches the target aircraft. The LWC starts with an enhanced aircraft simulation with a performance envelope that exceeds that of current inventory aircraft. The centrifuge is equipped with the flight controls necessary to fly the simulation in an air combat scenario. The display system is a high-resolution wide-field-of-view computer graphics system that is used to present a real-world gaming area, an aerial target aircraft, and a high-fidelity head-up display. The aerial target flies profiles that are either actual engagements recorded from air combat maneuvering ranges or flights recorded using the enhanced aircraft model simulation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Vegetable oils: a source of polyols for polyurethane materials (2016)

This manuscript is dedicated to the literature on vegetable oil-based polyurethanes via the isocyanate/alcohol route. A lot of efforts have been made to replace petroleum-based resources. Among renewable resources, vegetable oils present various advantages going from their availability to the large range of possible chemical modifications they permit. Firstly, the vegetable oil chemical composition and the main commercially available vegetable oil precursors are exposed. Concerning vegetable oils-based polyurethanes, research groups first focused on cross-linked systems directly from triglycerides then on thermoplastic ones from fatty acids or fatty acid methyl esters. This manuscript focuses on thermoplastic PUs and underlines the literature about the introduction of hydroxyl groups and isocyanate functions onto triglycerides and fatty acid derivatives. Besides, in a view to the isocyanate/alcohol approach, vegetable oil-based thermoplastic PUs and corresponding diols and diisocyanates are described in details.
Crystal tilting in GaN grown by pendoepitaxy method on sapphire substrate (1999)

Pendeoepitaxy of GaN on sapphire substrate with SiO2 mask is demonstrated and characterized by transmission electron microscopy and double crystal x-ray diffraction. A continuous layer of GaN with low dislocation density was achieved by this method. Parts of the GaN layer are tilted symmetrically toward [11-20] direction and have two kinds of coalesce and tilt boundaries. Each boundary was formed by a vertical array of piled up dislocations with the Burger’s vector of [11-20]. The tilting mechanism in pendeo-epitaxy is discussed in terms of surface interaction between the SiO2 mask and ELO-GaN.