gebhart/patrepeval huggingface dataset:
Comparison of the effects of amlodipine and diltiazem on 24-hour blood pressure, plasma catecholamines, and left ventricular mass. (1996)

In 30 patients with mild to moderate essential hypertension and high-normal left ventricular (LV) mass, the effects of treatment for 6 months with amlodipine (5 to 10 mg every morning) versus diltiazem-sustained release (SR) (90 to 180 mg twice daily) on 24-hour blood pressure (BP), plasma catecholamines, and echocardiographic estimates of LV mass and function were evaluated. Both amlodipine and diltiazem caused stable, persistent BP reduction over 24 hours with no evidence for a "peak" effect. For a similar decrease in diastolic BP, amlodipine caused a significantly larger decrease in systolic BP. Amlodipine decreased BP by lowering total peripheral resistance, whereas diltiazem caused small decreases in both total peripheral resistance and cardiac index. Both calcium antagonists caused modest but significant decreases in supine and standing plasma catecholamines. LV wall thickness and LV mass decreased significantly over the 6 months of follow-up: -6 +/- 2 with diltiazem and -10 +/- 2 g/m2 with amlodipine. In patients taking amlodipine, the decrease in LV mass correlated significantly with the decrease in plasma norepinephrine. In contrast to rapid-acting calcium antagonists, both amlodipine and diltiazem-SR cause smooth BP control and an appropriate decrease in LV mass without activation of the sympathetic nervous system.
Synthesis of the Sialidase Inhibitor Siastatin B (2000)

[structure] The resolved piperidinecarboxylate (R)-7 was converted to siastatin B (1) by an efficient and stereoselective sequence that includes a bromo-beta-lactonization and an N-acyliminium azidation. Two analogues (3 and 4) of siastatin were also prepared.
Use of Chloroethylene Carbonate as an Electrolyte Solvent for a Graphite Anode in a Lithium‐Ion Battery (1996)

Peer reviewed: Yes
Extended Strips Domain (2002)

The strips world is larger than the other domains; it includes ten object types and twenty-three operators (Figures 3.38-3.41). We have tested S haper with two linear and one nonlinear gain functions (Figure 12.1).
Array processing for channel equalization (2002)

An array of primitive programmable processors has been designed for high throughput reconfigurable signal processing. Each processor retains a primitive instruction set, minimal local storage, and exchanges data with adjacent processors using nearest neighbor communication. Several applications, including an adaptive filter with coefficient update using the least mean squares (LMS) algorithm, have been implemented and evaluated on an array of such processors. A multilayer processor mesh structure is used to accelerate summation of filter products. This paper describes the processor design, array interconnection, programming, and system integration issues, and concludes with the description of a functional LMS adaptive filter.
Assembly of Advanced Materials into 3D Functional Structures by Methods Inspired by Origami and Kirigami: A Review (2018)

Abstract Origami and kirigami, the ancient techniques for making paper works of art, also provide inspiration for routes to structural platforms in engineering applications, including foldable solar panels, retractable roofs, deployable sunshields, and many others. Recent work demonstrates the utility of the methods of origami/kirigami and conceptually related schemes in cutting, folding, and buckling in the construction of devices for emerging classes of technologies, with examples in mechanical/optical metamaterials, stretchable/conformable electronics, micro/nanoscale biosensors, and large‐amplitude actuators. Specific notable progress is in the deployment of functional materials such as single‐crystal silicon, shape memory polymers, energy‐storage materials, and graphene into elaborate 3D micro and nanoscale architectures. This review highlights some of the most important developments in this field, with a focus on routes to assembly that apply across a range of length scales and with advanced materials of relevance to practical applications.
Packet prioritization in multihop latency aware scheduling for delay constrained communication (2007)

This paper addresses the problem of optimizing the packet transmission schedule in a multihop wireless network with end-to-end delay constraints. The emphasis is to determine the proper relative weights assigned to the remaining distance and the remaining lifetime in order to rank the urgency of a packet. We consider a general class of cross-layer transmission schemes that represent such relative weights using a single lifetime-distance factor, which includes, as special cases, schedules such as earliest-deadline-first and largest-distance-first. We propose an analytical framework, based on recursive non-homogeneous Markovian analysis, to study the effect of the lifetime-distance factor on packet loss probability in a general multihop environment, with different configurations of peer-node channel contention. Numerical results are presented to illustrate how various network parameters affect the optimal lifetime-distance factor. We demonstrate quantitatively how the proper balance between distance and lifetime in a transmission schedule can significantly improve the network performance, even under imperfect schedule implementation.
Characteristics of nursing education in Hang Kong Polytechnic University and for our reference (2006)

Based on a brief introduction about the teaching psychology,curricular,teaching methods and teaching assessment of nursing education in Hong Kong Polytechnic University,some advises are given about how to improve and innovate the nursing education system,to set up the assessment system about the continuing nursing education and improve a more open teaching mode,and to enhance the international communication among universities in different countries.
Endogenous recovery after brain damage: molecular mechanisms that balance neuronal life/death fate (2015)

Neuronal survival depends on multiple factors that comprise a well-fueled energy metabolism, trophic input, clearance of toxic substances, appropriate redox environment, integrity of blood-brain barrier, suppression of programmed cell death pathways and cell cycle arrest. Disturbances of brain homeostasis lead to acute or chronic alterations that might ultimately cause neuronal death with consequent impairment of neurological function. Although we understand most of these processes well when they occur independently from one another, we still lack a clear grasp of the concerted cellular and molecular mechanisms activated upon neuronal damage that intervene in protecting damaged neurons from death. In this review, we summarize a handful of endogenously activated mechanisms that balance molecular cues so as to determine whether neurons recover from injury or die. We center our discussion on mechanisms that have been identified to participate in stroke, although we consider different scenarios of chronic neurodegeneration as well. We discuss two central processes that are involved in endogenous repair and that, when not regulated, could lead to tissue damage, namely, trophic support and neuroinflammation. We emphasize the need to construct integrated models of neuronal degeneration and survival that, in the end, converge in neuronal fate after injury. Under neurodegenerative conditions, endogenously activated mechanisms balance out molecular cues that determine whether neurons contend toxicity or die. Many processes involved in endogenous repair may as well lead to tissue damage depending on the strength of stimuli. Signaling mediated by trophic factors and neuroinflammation are examples of these processes as they regulate different mechanisms that mediate neuronal demise including necrosis, apoptosis, necroptosis, pyroptosis and autophagy. In this review, we discuss recent findings on balanced regulation and their involvement in neuronal death.
Functional neuromuscular stimulation system using an implantable hydroxyapatite connector and a microprocessor-based portable stimulator (1989)

For developing functional neuromuscular stimulation (FNS) orthoses, percutaneous implants made of sintered hydroxyapatite (HAp) and a microprocessor-based portable stimulator were devised, and related basic studies were carried out. First, a button-shaped HAp was percutaneously implanted up to 23 months in the skin of dogs, and 30 months in human subjects. The HAp was closely contacted with the skin tissue. Then, button-shaped HAp electrical connectors were percutaneously implanted in the skin of rabbits. Sufficient contractions of the calf muscle were elicited by electrical stimuli delivered to intramuscular electrodes through the connector. These results indicated that the HAp electrical connector could be clinically utilized as an implantable skin interface for FNS. The microprocessor-based stimulator capable of processing control command signals and delivering 16-channels of electrical stimuli was developed. Usefulness of the stimulator was demonstrated by applying it to flexor and extensor muscles of the thumb in a C5 quadriplegic patient.
Tumor Necrosis Factor-α Converting Enzyme/ADAM 17 Mediates MUC1 Shedding (2003)

MUC1 clearance from the uterine epithelial cell surface is a prerequisite for the creation of an environment conducive to embryo implantation. In some species, reduced mRNA levels along with metabolic turnover account for loss of MUC1 during the receptive phase throughout the uterine epithelium. In other species, MUC1 is rapidly lost solely at the site of blastocyst attachment, suggesting the action of a protease. Correlative studies also indicate the presence of soluble forms of MUC1 in cell culture supernatants in vitro and in bodily fluids in vivo. To characterize the proteolytic activity mediating MUC1 release, shedding of MUC1 was analyzed in a human uterine epithelial cell line (HES) that abundantly expresses and readily sheds MUC1. MUC1 release was stimulated by phorbol 12-myristate 13-acetate and was markedly inhibited by the synthetic peptide hydroxamate metalloprotease inhibitor, tumor necrosis factor-alpha protease inhibitor (TAPI), as well as by an endogenous inhibitor of matrix metalloproteases, tissue inhibitor of metalloproteases (TIMP)-3. These characteristics along with studies conducted with cell lines genetically deficient in various ADAMs (for a disintegrin and metalloprotease) identified tumor necrosis factor-alpha converting enzyme (TACE)/ADAM 17 as a MUC1 sheddase. Furthermore, both TACE and MUC1 were expressed in human uterine epithelia during the receptive phase, and co-immunoprecipitation experiments revealed a physical interaction between TACE and MUC1 in HES cells. These studies establish a proteolytic mechanism for MUC1 clearance from a human uterine epithelial cell line and identify TACE as a MUC1 sheddase.
Monomer Sequence Distribution in Ethylene-Propylene Rubber Measured by <sup>13</sup>C NMR. 3. Use of Reaction Probability Model (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMonomer Sequence Distribution in Ethylene-Propylene Rubber Measured by 13C NMR. 3. Use of Reaction Probability ModelC. J. Carman, R. A. Harrington, and C. E. WilkesCite this: Macromolecules 1977, 10, 3, 536–544Publication Date (Print):May 1, 1977Publication History Published online1 May 2002Published inissue 1 May 1977https://pubs.acs.org/doi/10.1021/ma60057a008https://doi.org/10.1021/ma60057a008research-articleACS PublicationsRequest reuse permissionsArticle Views1327Altmetric-Citations178LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Image segmentation using support vector machine (2005)

Image segmentation is a necessary step in image analysis. Support vector machine is considered a good candidate because of its good generalization performance, especially when the number of training samples is very small and the dimension of feature space is very high. The presented paper investigates image segmentation using support vector machine. Experimental results show that Support vector machine is a promising technique in image segmentation.
Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma (2002)

The frequency of brain metastases in this cohort was highest in patients with lung carcinoma, followed by patients with renal carcinoma. There was no evidence of an increasing incidence of brain metastasis in patients with carcinoma of the breast or lung.
EX VIVO EXPANDED HUMAN Vλ9Vδ2+ λδ-T CELLS MEDIATE INNATE ANTITUMOR ACTIVITY AGAINST HUMAN PROSTATE CANCER CELLS IN VITRO (2005)

Ex vivo, expanded human Vgamma9Vdelta2+ gammadelta-T cells are able innately to recognize and kill certain human prostate tumor cell lines in vitro. The recognition and killing of prostate cancer cells occurs in a gammadelta-T-cell receptor dependent manner and it also appears to involve interactions between ICAM-1 and CD18. Because apoptosis resistant human Vgamma9Vdelta2+ gammadelta-T cells can readily be expanded to large numbers (clinical scale), these findings must be considered in the context of developing adoptive immunotherapy strategies to exploit gammadelta-T cell innate immune responses to prostate cancer.
Relationships and Taxonomic Status of Alternaria radicina, A. carotiincultae, and A. petroselini Based upon Morphological, Biochemical, and Molecular Characteristics (2002)

Alternaria radicina, A. carotiincultae, and A. petroselini are closely related pathogens of umbelliferous crops. Relationships among these fungi were determined based on growth rate, spore morphology, cultural characteristics, toxin production, and host range. Random amplified polymorphic DNA (RAPD) analysis of these species, other species of Alternaria, and closely related fungi was also performed. A. petroselini was readily differentiated from A. radicina and A. carotiincultae on the basis of spore morphology, production of microsclerotia, host range, and RAPD analysis. Alternaria radicina and A. carotiincultae were considerably more similar to each other than to A. petroselini, but could be differentiated on the basis of growth rate, spore morphology, colony morphology, and, to a limited extent, RAPD analysis. When grown on media having a high nutritional content, A. radicina produced a diffusible yellow pigment and crystals of the fungal metabolite radicinin. In contrast, A. carotiincultae produced little or no radicinin. However, when A. carotiincultae was grown on the same medium amended with radicinin, growth rate and colony and conidial morphology were more similar to those of A. radicina. These results suggest that the morphological differences between A. radicina and A. carotiincultae are due, at least in part, to radicinin production, and that these fungi are conspecific. Therefore, we propose that A. carotiincultae be considered a synonym of A. radicina.
G, hard or soft (1906)

G, hard or soft Get access F. W. Read F. W. Read Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s10-VI, Issue 143, 22 September 1906, Page 236, https://doi.org/10.1093/nq/s10-VI.143.236c Published: 22 September 1906
A framework for adaptive process modeling and execution (FAME) (2002)

The paper describes the architecture and concept of operation of a Framework for Adaptive Process Modeling and Execution (FAME). The research addresses the absence of robust methods for supporting the software process management life cycle. FAME employs a novel, model based approach in providing automated support for different activities in the software development life cycle, including project definition, process design, process analysis, process enactment, process execution status monitoring, and execution status-triggered process redesign. FAME applications extend beyond the software development domain to areas such as agile manufacturing project management, logistics planning, and business process reengineering.
The Role of Hypoxia-Induced miR-210 in Cancer Progression (2015)

Prolonged hypoxia, the event of insufficient oxygen, is known to upregulate tumor development and growth by promoting the formation of a neoplastic environment. The recent discovery that a subset of cellular microRNAs (miRs) are upregulated during hypoxia, where they function to promote tumor development, highlights the importance of hypoxia-induced miRs as targets for continued investigation. miRs are short, non-coding transcripts involved in gene expression and regulation. Under hypoxic conditions, miR-210 becomes highly upregulated in response to hypoxia inducing factors (HIFs). HIF-1α drives miR-210's overexpression and the resultant alteration of cellular processes, including cell cycle regulation, mitochondria function, apoptosis, angiogenesis and metastasis. Here we discuss hypoxia-induced dysregulation of miR-210 and the resultant changes in miR-210 protein targets that regulate cancer progression. Potential methods of targeting miR-210 as a therapeutic tool are also explored.
REPOSITIONING INFORMATION: An Interview with Pat Sabosik, Editor and Publisher, <i>Choice</i> (1993)

On March 12, 1992, Choice sponsored a collection development workshop for members of the New England Chapter of the Association of College and Research Libraries. At that meeting, Pat Sabosik outlined a future publishing strategy for Choice. It explored many facets of reference, bibliographic, and electronic publishing that are of vital interest to librarians in their search for ways to disseminate information. It also addressed some issues relating to finance and publishing. For these reasons, Bottom Line decided to follow up with a longer interview.
VisHap: augmented reality combining haptics and vision (2004)

Haptic devices have been successfully incorporated into the human-computer interaction model. However, a drawback common to almost all haptic systems is that the user must be attached to the haptic devices at all times even though force feedback is not always being rendered. This constant contact hinders perception of the virtual environment, primarily because it prevents the user from feeling new tactile sensations upon contact with virtual objects. We present the design and implementation of an augmented reality system called VisHap that uses visual tracking to seamlessly integrate force feedback with tactile feedback to generate a "complete" haptic experience. The VisHap framework allows the user to interact with combinations of virtual and real objects naturally, thereby combining active and passive haptics. An example application of this framework is also presented. The flexibility and extensibility of our framework is promising in that it supports many interaction modes and allows further integration with other augmented reality system.
Allerlei Trends: die neuesten Entwicklungen in der Riechstoffchemie (2000)

Neben der nahe verwandten Chemie der Aromen ist die Riechstoffchemie eine der wenigen Bereiche, wenn nicht gar der einzige, in denen der Chemiker unmittelbar Struktur-Wirkungs-Beziehungen erfahren kann. Dieser Aufsatz stellt Struktur-Geruchs-Beziehungen und Olfaktophor-Modelle für alle wichtigen Geruchsrichtungen der Parfümerie vor: „fruchtig“, „grün“, „marin“, „blumig“, „würzig“, „holzig“, „Ambra“ und „Moschus“. Neue Trendsetter und so genannte captive Riechstoffe dieser Geruchsnoten werden vorgestellt und die jüngsten Aktivitäten und Highlights im Bereich der Riechstoffchemie zusammengefasst. Das Maßschneidern von Riechstoffen, ihre chemischen Synthesen und ihre Verwendung in der modernen Parfümerie werden ebenfalls behandelt. Unsere Auswahl wurde bestimmt von und illustriert mit kreativen Parfümkompositionen, und die neuen Riechstoffe, die die aktuellen Trends setzten, werden hervorgehoben. Neue Riechstoffe für Grapefruit- und Johannisbeerakkorde, für Galbanum- und Blätterkopfnoten werden behandelt. Und Substanzen mit modischen marinen, ozonigen und aquatischen Facetten kommen ebenso zur Sprache wie neue Riechstoffe für die klassischen Maiglöckchen-, Rosen- und Jasminakkorde. Verbindungen süßer und würziger Duftrichtungen fehlen genausowenig wie die neuesten Entwicklungen im Bereich der Holznoten, wie etwa Sandelholz und Vetiver. Wir schließen unseren Überblick ab mit Moschus- und Ambra-Riechstoffen, die ungewöhnliche Strukturmerkmale aufweisen. Einige Dufttrends und parfümistische Effekte werden anhand von mikroverkapselten Duftproben illustriert, und außerdem wird hervorgehoben, in welchen Bereichen der größte Bedarf für neue Parfümrohstoffe oder Synthesestrategien besteht. Unser Ziel ist es, Chemiker für Themen aus der Riechstoffchemie zu begeistern und sie teilhaben zu lassen am Entwurf und der Synthese neuer Riechstoffe. Dieser Aufsatz gibt einen aktuellen Überblick über das Gesamtgebiet.
A Survey on Wi-Fi Based Contactless Activity Recognition (2016)

Providing accurate information about human's state, activity is one of the most important elements in Ubiquitous Computing. Various applications can be enabled if one's state, activity can be recognized. Due to the low deployment cost, non-intrusive sensing nature, Wi-Fi based activity recognition has become a promising, emerging research area. In this paper, we survey the state-of-the-art of the area from four aspects ranging from historical overview, theories, models, key techniques to applications. In addition to the summary about the principles, achievements of existing work, we also highlight some open issues, research directions in this emerging area.
Effect of bacterial, urine and substratum surface tension properties on bacterial adhesion to biomaterials (1991)

A type I and P fimbriated uropathogenic Escherichia coli Hu734 was found to be more hydrophilic than Staphylococcus epidermidis 1938 and Lactobacillus acidophilus T‐13. The correlation with substrata surface tension and adhesion was linear only for the lactobacillus. There was no evidence that patients with a history of recurrent urinary tract infections had urinary surface tensions consistently higher or lower than healthy controls. However, relative surface tensions differed by up to 21 mJ‐m"2 between urine samples from patients. Free energy of adhesion values demonstrated that bacterial culture conditions could alter the adhesion potential. In addition, hydrophilic E. coli were found more likely to adhere to hydrophilic substrata in urine of low surface tension. L. acidophilus T‐13 were more likely to adhere to biomaterials than E. coli, when the urinary surface tension was high. The findings indicate the complexity of the process of bacterial adhesion related to catheter‐associated urinary tract infections.