gebhart/patrepeval huggingface dataset:
Nonenzymatic glycosylation: role in the pathogenesis of diabetic complications. (1986)

Prolonged hyperglycemia is the primary metabolic abnormality responsible for the development of irreversible tissue damage in chronic diabetes. However, patients with similar levels of chronic hyperglycemia can differ markedly in their susceptibility to diabetic complications. Among the mechanisms by which hyperglycemia may lead to tissue damage, nonenzymatic glycosylation involves excessive chemical attachment of glucose to proteins without the involvement of enzymes. The early Amadori products, resembling hemoglobin A1c, slowly give rise to complex irreversible glycosylation adducts. Only these post-Amadori products accumulate in diabetic tissues over long periods. However, early nonenzymatic glycosylation or Amadori product formation can alter such physiological processes as enzyme activity or binding of regulatory molecules. Advanced glycosylation end products can covalently trap extravasated serum proteins to the extravascular matrix, and thus may contribute to capillary closure in the retina and glomerulus, and to arterial narrowing in the coronary, cerebral, and peripheral circulation. Although a macrophage receptor system may antagonize this glycosylation-mediated accumulation of proteins by recognizing and ingesting those proteins with advanced glycosylation end products, excessive formation of those proteins in diabetes may saturate the capacity of the macrophage removal system.
Integration of optimized low-pass filters in a bandpass filter for out-of-band improvement (2001)

In this paper, we discuss the control and suppression of spurious resonances commonly encountered with distributed bandpass filters. The basic idea consists of introducing low-pass structures within bandpass topologies. By adjusting low-pass filter cutoff frequencies, harmonic resonances are attenuated, while maintaining in-band performances. In addition, transmission losses may be reduced as the insertion technique leads to optimum designs in terms of overall size. The approach described here is based upon the combination of classical synthesis techniques and optimization procedures provided by conventional computer-aided-design tools. Experimental results are obtained in the case of /spl lambda//sub g//4 shunt-stub filters implemented in classical semilumped low-pass architectures. Then, we investigate alternative integration technologies and techniques to improve the out-of-band rejection over very wide operating bandwidth. To overcome some design limitations, i.e., workable characteristic impedance value, we propose and validate a multilayer solution. Finally, new low-pass topologies are suggested to improve low-pass filter band rejection.
SUBSTRATE INTEGRATED WAVEGUIDE FREQUENCY-AGILE SLOT ANTENNA AND ITS MULTIBEAM APPLICATION (2012)

A new technique for designing the substrate integrated waveguide (SIW) frequency-agile slot antenna is presented in this paper. Similar to the metallic waveguide counterpart, the SIW is a uniconductor guided-wave structure and inherently difficult in the electronically tunable applications. To solve this problem, a single slot etched on the top conductor layer of a conventional antenna is instead of two slots to construct an isolated area, which is convenient for the DC bias. The electric length of slots can then be adjusted through two shunt varactors welded near the center of slot. As such, a SIW frequency-agile slot antenna is realized and fabricated to cover the frequency of 2.30 2.74 GHz with different bias voltages. Experiments verify our theory analysis and design process. Then, a frequency-agile multibeam antenna is developed to cover several frequency bands while switching between four different radiation patterns pointing at different spatial locations for each frequency. It presents an excellent candidate for software and cognitive radio system applications.
2-and 3-Phenylthionaphthens (1959)

The product obtained from 3-(1'-cyclohexenyl)thionaphthen (I) by dehydrogenation with sulphur at 240-250 °C is shown to be 2-phenylthionaphthen rather than 3-phenyl-thionaphthen (II) as assumed by Schuetz and Ciporin (1958a, 1958b). The dissimilarity of the ultraviolet absorption spectra of 2- and 3-phenylthionaphthens is discussed.
Elevated Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-2 in Malignant Pleural Effusion (2002)

Insulin-like growth factor-1 (IGF-1) and its binding proteins (IGFBPs) are produced by many tissues and are present in serum and other biological fluids. Alterations in sera of IGF-1 and 2 and IGFBPs were demonstrated in patients with malignancy, infection and other diseases causing pleural effusion. In this study the IGF-1 and IGFBP-2 content and the specific electrophoretic patterns of IGFBPs in samples of sera and pleural effusions of 25 patients with malignancy, infection and congestive heart failure were investigated. IGF-1 levels in exudative effusions of malignant solid tumors were significantly higher [(mean +/- SD), 20.9+/-7.5 nmol/L, n = 9] than in lymphoma (11.0+/-5.2 nmol/L, n = 5; p < 0.05), infection (11.4+/-6.5 nmol/L, n = 6; p < 0.05) and transudative effusion of congestive heart failure (4.3+/-3.3 nmol/L, n = 5; p < 0.02). IGFBP-2 was markedly increased in effusions of malignant solid tumors (2.14+/-0.82 mg/L, n = 9) compared with exudates of lymphoma, infection and transudates (1.10+/-0.70, 1.22+/-0.32 and 0.93+/-0.52 nmol/L, respectively, p < 0.05). Moreover, in effusion of solid tumors, IGFBP-2 levels were higher than those in corresponding sera, which suggests local production of this binding protein. The demonstration of IGFBP-2 in solid tumor cells by immunohistochemistry further supports this possibility. This work demonstrates the existence of the IGF-1/IGFBP system in pleural fluids from different etiologies and implies possible use of IGF-1 and IGFBP-2 as a potential marker of malignant effusions.
Advance in reverse gyrase from hyperthermophiles (2000)

Reverse gyrases exist in hyperthermophiles. They are type I-5^ topoisomerases whichenable to induce DNA to form positive superhelixes. Sequencing of the genus encoding reverse gyrase suggested that reverse gyrases are constituted of two distinct domains: a C-terminal domain of an ATP-independent type I topoisomerase and a N-terminal domain of an ATP-independent helicase-like module. It is believed that positive superhelix is catalyzed by the concerted action of the helicase module and topoisomerase module in the same polypetide. Phylogenetic analysis shows that all known reverse gyrases so far commonly form a new branch of tye I-5^ topoisomerase-TopR.
Anatomy of high-performance deep learning convolutions on SIMD architectures (2018)

Convolution layers are prevalent in many classes of deep neural networks, including Convolutional Neural Networks (CNNs) which provide state-of-the-art results for tasks like image recognition, neural machine translation and speech recognition. The computationally expensive nature of a convolution operation has led to the proliferation of implementations including matrix-matrix multiplication formulation, and direct convolution primarily targeting GPUs. In this paper, we introduce direct convolution kernels for x86 architectures, in particular for Xeon and Xeon Phi systems, which are implemented via a dynamic compilation approach. Our JIT-based implementation shows close to theoretical peak performance, depending on the setting and the CPU architecture at hand. We additionally demonstrate how these JIT-optimized kernels can be integrated into a light-weight multi-node graph execution model. This illustrates that single- and multi-node runs yield high efficiencies and high image-throughputs when executing state-of-the-art image recognition tasks on CPUs.
Using lung sounds in classification of pulmonary diseases according to respiratory subphases (2005)

Auscultation-based diagnosis of pulmonary disorders relies heavily on the presence of adventitious sounds and on the altered transmission characteristics of the chest wall. The phase information of the respiratory cycle within which adventitious sounds occur is very helpful in diagnosing different diseases. In this study, respiratory sound data belonging to four pulmonary diseases, both restrictive and obstructive, along with healthy respiratory data are used in various classification experiments. The sound data are separated into six subphases, namely, early, mid, late inspiration and expiration and classification experiments using a neural classifier are carried out for each subphase. The AR parameters acquired from segmented sound signals, prediction error and the ratio of expiration to inspiration durations are used to construct the feature set to the neural classifier. Classification experiments are carried out between healthy and pathological sound segments, between restrictive and obstructive sound segments and between two different disease sound segments. The results indicate that the classifier performance demonstrates subphase dependence for different diseases. These results may shed light in eliminating redundant feature spaces in building an expert system using lung sounds for pulmonary diagnosis.
Multicast in SMDS over an ATM network (2003)

It is shown that an asynchronous transfer mode (ATM) network architecture equipped with connectionless servers at the ATM switches is suitable for switched multimegabit data service (SMDS) support. A multicast tree computation scheme based on the underlying routing procedure is proposed. Two different address handling methods-encapsulation and nonencapsulation-are considered, and their effectiveness in providing multicast service is compared.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Neuroprotection of the Brain During Cardiopulmonary Bypass (1998)

This is the first study to show statistically significant drug-based neuroprotection during cardiac surgery. In addition to offering improvement in cerebral outcome for such at-risk patients, it supports the hypothesis that drugs acting on the excitotoxic mechanism of ischemic cerebral damage can be effective in humans.
Cross-project defect prediction using a connectivity-based unsupervised classifier (2016)

Defect prediction on projects with limited historical data has attracted great interest from both researchers and practitioners. Cross-project defect prediction has been the main area of progress by reusing classifiers from other projects. However, existing approaches require some degree of homogeneity (e.g., a similar distribution of metric values) between the training projects and the target project. Satisfying the homogeneity requirement often requires significant effort (currently a very active area of research).
Sparse Inverse Covariance Matrices for Low Resource Speech Recognition (2012)

We propose to use sparse inverse covariance matrices for acoustic model training when there is insufficient training data. Acoustic models trained with inadequate training data tend to over fit, generalizing poorly to unseen test data, especially when full covariance matrices are used. We address this problem by adding an L1 regularization term to the traditional objective function for maximum likelihood estimation, to penalize complex models. The structure of the inverse covariance matrices will be automatically sparsified using this new objective function. The Expectation Maximization algorithm is used to learn the parameters of the hidden Markov model using the new objective function. It is shown that the training procedures for all the hidden Markov model parameters are the same as that of maximum likelihood estimation except the inverse covariance matrices. The update equation for the inverse covariance matrices is concave and can be solved efficiently. Our experiments show that this proposed method can correctly learn the underlying correlations among the random variables of the speech feature vector. Experimental results on the Wall Street Journal data show that our proposed model significantly outperforms the diagonal covariance model and the full covariance model by 10.9% and 16.5% relative recognition accuracy, when only about 14 hours of training data are available. On our collected low resource language data-the Cantonese data set, the proposed model also significantly outperforms the diagonal covariance model and the full covariance model.
High‐Density Yttria for Practical Ceramic Applications (1992)

This paper describes a process by which highly reactive yttria powder can be sintered to high density at a relatively low firing temperature to form a variety of useful ceramic items. The process utilizes an aqueous polymer to precipitate a yttrium precursor. The yttrium precursor is thermally treated to form a friable oxide ash. After a double‐calcination‐grind procedure, high‐density yttria items such as substrates, crucibles, and nozzles can be fabricated.
Trends in the Indications for Penetrating Keratoplasty in the Midwestern United States (2000)

Pseudophakic bullous keratopathy was the leading indication for PKP in our series. This is in agreement with the data reported in other similar studies done in North America. However, unlike most of these studies, our second leading indication was Fuchs' dystrophy. This contrast may be secondary to different genetic demographics in the midwestern United States.
Using dynamic cache management techniques to reduce energy in a high-performance processor (1999)

Article Using dynamic cache management techniques to reduce energy in a high-performance processor Share on Authors: Nikolaos Bellas Department of Electrical & Computer Engineering and the Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, IL Department of Electrical & Computer Engineering and the Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, ILView Profile , Ibrahim Hajj Department of Electrical & Computer Engineering and the Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, IL Department of Electrical & Computer Engineering and the Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, ILView Profile , Constantine Polychronopoulos Department of Electrical & Computer Engineering and the Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, IL Department of Electrical & Computer Engineering and the Coordinated Science Laboratory, University of Illinois at Urbana-Champaign, 1308 West Main Street, Urbana, ILView Profile Authors Info & Claims ISLPED '99: Proceedings of the 1999 international symposium on Low power electronics and designAugust 1999 Pages 64–69https://doi.org/10.1145/313817.313856Online:17 August 1999Publication History 59citation448DownloadsMetricsTotal Citations59Total Downloads448Last 12 Months6Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Deep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3′ Trailers (2010)

Our results provide the first comprehensive view of the subcellular distribution of diverse sRNAs and new insights into the roles of miRNAs and tRNA 3' trailers in the cell.
Scattering experiments at the Ipswich electromagnetic measurements facility: Calibration with perfectly conducting spheres (1983)

Abstract : A new electromagnetic scattering facility located at Ipswich, Massachusetts is described. A 20 x 20 x 40 ft anechoic chamber was evaluated as to wall reflection coefficient at 10, 35, 98, and 140 GHz. The frequency stability of the measurement equipment was evaluated and was determined not to be a limiting factor in making radar cross section measurements. The backscatter radar cross sections of 24 metal spheres were measured at 10 GHz and compared with theory. The spheres ranged in size from 0.218 to 8.00 inches in diameter, corresponding to a Ka range of 0.581 to 21.293. The measured radar cross sections differed from theory by less than 0.6 dB. Radar cross sections as low as -46 dBsm were measured. The calibrated facility will be used to measure canonical shapes for both metallic and non-metallic targets. The non-metallic results will be used for the Cruise Missle Surveillance Program. (Author)
Modified Corn—Will Livestock Producers Buy It? (2015)

Livestock producers are efficient producers who use feed rations containing the lowest cost (or least-cost) nutritive additives. As a group, they have not shown a willingness to pay a premium for feed grown from specialty seed that has been modified to meet the nutritional needs of different livestock species in different regions of the country. Will these producers ever be prepared to pay the premiums required to pull identity-preserved feed grains through the pipeline?
Power allocation over parallel Gaussian multiple access and broadcast channels (2006)

In this correspondence, we determine the optimal power allocation, that achieves any specified point on the boundary of the capacity region, for sets of parallel Gaussian multiple-access channels (MACs) and sets of parallel Gaussian broadcast channels (BCs). The power allocation is across the parallel channels and, within each channel, across the users. In both cases, there is a single constraint on the total power used. First, the allocation for the parallel MACs is determined, in a simple form, using the Karush-Kuhn-Tucker (KKT) conditions and a simple Lagrangian argument. Using this result, the allocation for the parallel BCs is derived using recent findings on the duality of the MAC and BC.
Reconstructing Activity Location Sequences From Incomplete Check-In Data: A Semi-Markov Continuous-Time Bayesian Network Model (2017)

Geo-location data from the check-ins made in online social media offers us information, in new ways, to understand activity-location choices of a large number of people. However, one of the major challenges of using check-in data is that it has missing activities, since users share their activities voluntarily. In this paper, we present a probabilistic modeling approach to reconstruct user activity-location sequences from this incomplete activity participation information. Specifically, we answer the question of how to predict an individual's next activity, its duration and location given the incomplete trajectory data. The model describes the dynamics of individual activity participation behavior evolving over continuous time. A semi-Markov modeling approach is used to capture the stochastic processes involved in the activity generation mechanism. We present a particle-based Markov chain Monte Carlo sampler to run inference over the model. We further develop an expectation-maximization algorithm to learn the unknown parameters of the model from incomplete trajectory data. Finally, the method is applied to synthetically generated activity-location sequences and a data set of Foursquare check-ins of the users from New York City. Our experiments show that this method can successfully extract the true transition and duration distributions given the incomplete trajectory information. The proposed approach can help building many intelligent transportation applications using check-in data.
Traffic masking in IPsec: architecture and implementation (2007)

Protection from statistical traffic analysis attacks calls for effective design of traffic flow confidentiality (TFC) mechanisms. These are devised to alter the traffic pattern in order to hide information about contents transmitted, which, despite encryption, can be revealed by malicious users through statistical analysis. Widespread diffusion of these mechanisms requires embedding them in widely deployed protocols. This paper proposes an IPsec based framework aimed at enforcing TFC. This is characterized by two key components: i) a module designed to enforce packet padding, fragmentation, dummy packet generation, and artificial alteration of the packet forwarding delay, and ii) a TFC header devised to carry information across the IPsec tunnel to allow packet handling at the receiver side. The proposed approach has been implemented in a Linux 2.6 Kernel, and preliminary experimental results are reported to show its operation.
Benefit of a Commercially Available Cochlear Implant Processor With Dual-Microphone Beamforming (2012)

The results of the study suggest that the Nucleus 5 sound processor provides significantly better speech recognition in quiet and in noise when compared with performance with the Nucleus Freedom processor.
Effect of blade curvature on the hemolytic and hydraulic characteristics of a centrifugal blood pump (2018)

Introducing a blade curvature enhanced the hydrodynamic and hemolytic performance compared to the straight-blade configuration for the investigated centrifugal blood pump. The findings of this study provide new insights into centrifugal blood pump design by examining the influence of the blade curvature.
Homology-Dependent Silencing of the <i>SC3</i> Gene in <i>Schizophyllum commune</i> (1997)

After introduction of extra copies of the SC3 hydrophobin gene into a wild-type strain of Schizophyllum commune, gene silencing was observed acting on both endogenous and introduced SC3 genes in primary vegetative transformants. Nuclear run-on experiments indicated that silencing acted at the transcriptional level. Southern analysis revealed that cytosine methylation of genomic DNA occurred. Moreover, SC3 silencing was suppressed by exposure to 5-azacytidine during growth. After growth of SC3-suppressed colonies from homogenized mycelium or from colonies stored at 4 degrees, SC3 transcription was restored. However, after prolonged growth SC3 silencing was again observed. Introduction of a promoterless SC3 fragment into wild type gave less SC3 silencing.
Toward the Resolution of the Controversy Surrounding the Effects and Social Health Implications of Marijuana Use (1974)

The controversy over marijuana continues unabated because of two primary factors: 1) the widespread lack of knowledge and understanding among the general public concerning many of the lesser known effects of marijuana, and 2) the failure to deal with basic issues concerned with the value of individual and social health and society's role in safeguarding the health of the individual and the nation. Problems in communication which have impeded resolution of the controversy and social policy implications of the effects of marijuana use are discussed.
Achieving the Welch Bound With Difference Sets (2005)

Consider a codebook containing N unit-norm complex vectors in a K-dimensional space. In a number of applications, the codebook that minimizes the maximal cross-correlation amplitude (I/sub max/) is often desirable. Relying on tools from combinatorial number theory, we construct analytically optimal codebooks meeting, in certain cases, the Welch lower bound. When analytical constructions are not available, we develop an efficient numerical search method based on a generalized Lloyd algorithm, which leads to considerable improvement on the achieved I/sub max/ over existing alternatives. We also derive a composite lower bound on the minimum achievable I/sub max/ that is effective for any codebook size N.