gebhart/patrepeval huggingface dataset:
A fuzzy TOPSIS approach with subjective weights and objective weights (2007)

Abstract:- Multiple criteria decision making (MCDM) is widely used in ranking one or more alternatives from a set of available alternatives with respect to multiple criteria. Inspired by MCDM which are methods to systematically evaluate alternatives, we propose a new Fuzzy TOPSIS for evaluating outsourcing software companies both using subjective and objective weights. While crisp data are inadequate to model the real life situations in MCDM, decision makers (DM) use linguistic variables to describe the important degrees of specific attributes. We also present the same TOPSIS method by using an entropy-based weighting approach. With our method, we provide decision makers more information to make more subtle decisions.
Brayton-Cycle Baseload Power Tower CSP System (2013)

The primary objectives of Phase 2 of this Project were:1. Engineer, fabricate, and conduct preliminary testing on a low-pressure, air-heating solar receiver capable of powering a microturbine system to produce 300kWe while the sun is shining while simultaneously storing enough energy thermally to power the system for up to 13 hours thereafter. 2. Cycle-test a high-temperature super alloy, Haynes HR214, to determine its efficacy for the system’s high-temperature heat exchanger. 3. Engineer the thermal energy storage system. This Phase 2 followed Wilson’s Phase 1, which primarily was an engineering feasibility study to determine a practical and innovative approach to a full Brayton-cycle system configuration that could meet DOE’s targets. Below is a summary table of the DOE targets with Wilson’s Phase 1 Project results. The results showed that a Brayton system with an innovative (low pressure) solar receiver with ~13 hours of dry (i.e., not phase change materials or molten salts but rather firebrick, stone, or ceramics) has the potential to meet or exceed DOE targets. Such systems would consist of pre-engineered, standardized, factory-produced modules to minimize on-site costs while driving down costs through mass production. System sizes most carefully analyzed were in the range of 300 kWe to 2 MWe. Such systems would also use off-the-shelf towers, blowers, piping, microturbine packages, and heliostats. Per DOE’s instructions, LCOEs are based on the elevation and DNI levels of Daggett, CA, for a 100 MWe power plant following 2 GWe of factory production of the various system components.
Distinct Applications of MWD, Weight on Bit, and Torque (1993)

Summary Recent enhancements to measurement-while-drilling (MWD) tools have increased drilling efficiency in directional wells on the North Slope of Alaska. With information provided by downhole weight on bit (WOB) and torque sensors, more timely and accurate decisions have been made, resulting in lower costs per foot. Specific applications of this technology include bit optimization, directional feedback, and drillstring-friction analysis. This paper discusses actual cases where the use of data from these downhole sensors has improved drilling performance. This information will benefit those interested in optimizing polycrystalline-diamond-compact (PDC) and rollercone bit runs, improving directional-drilling assembly predictability and performance, minimizing surface torques, and planning high-departure wells.
Polymer solar cells based on copolymers of dithieno[3,2-b:2′,3′-d]silole and thienopyrroledione (2011)

Novel low band gap copolymers based on dithienosilole and thienopyrroledione units were synthesized. Copolymer P1 with branched side chains on the TPD units demonstrated a PCE of 4.4% with a high V(oc) of 0.89 V for OPV applications while OTFT devices fabricated from a copolymer containing linear side chains (P2) performed better in OTFT device configurations.
Effect of time-delay errors on the beam pattern of a linear array (1985)

In conventional time-domain beam forming with sampled receiver outputs, the delays required to steer a beam in a given direction can only be approximated to within the nearest half sampling interval. For a linear array of equispaced receivers, and for certain directions, these errors give rise to high isolated sidelobes in the beam pattern. A model describing this beam pattern is used to predict the number, position, and height of these sidelobes. Degradation of the height of the main lobe is also considered. For coarse quantization, and in the absence of interpolation, the model suggests a recursive beamformer structure which significantly reduces the number of additions required. A simple interpolation scheme which reduces the height of these sidelobes is discussed and an Efficient scheme for implementing such interpolation is given.
Efficient extraction of human motion volumes by tracking (2010)

We present an automatic and efficient method to extract spatio-temporal human volumes from video, which combines top-down model-based and bottom-up appearance-based approaches. From the top-down perspective, our algorithm applies shape priors probabilistically to candidate image regions obtained by pedestrian detection, and provides accurate estimates of the human body areas which serve as important constraints for bottom-up processing. Temporal propagation of the identified region is performed with bottom-up cues in an efficient level-set framework, which takes advantage of the sparse top-down information that is available. Our formulation also optimizes the extracted human volume across frames through belief propagation and provides temporally coherent human regions. We demonstrate the ability of our method to extract human body regions efficiently and automatically from a large, challenging dataset collected from YouTube.
Wireless P2P: Problem or Opportunity? (2010)

Abstract—P2P is currently considered a problem by many wired and wireless providers, especially because of the large amount of traffic it generates. However, given new technology developments such as Wi-Fi Direct, we see an opportunity for P2P in mobile settings that, rather than treating mobiles as second-class citizens, seeks to take advantage of their capabilities over stationary devices. In this paper, we outline a new approach for fully decentralized mobile P2P that allows mobiles to run a variety of services and at the same time alleviates data overload in mobile networks. We consider mobiles integral and a richer class of nodes, and assume that they are capable of forming P2P networks without necessarily relying on the aid of stationary hosts or servers. We present a new architecture based on JXTA middleware, which is meant to not only optimize mobile resources, but also aims to take full advantage of the features that mobiles offer, such as mobility, ubiquity, location-awareness and sensors. Keywords-Wireless; Peer-To-Peer; Mobiles; Broadbands. I.
Coherence dependence of fiber-optic laser Doppler velocimeter output using self-mixing laser diode (2002)

A new laser Doppler velocimeter (LDV) employing a self-mixing laser diode (SM-LD), which has a long optical fiber of 10 m to 1 km, as a light guide. This new LDV can measure a Doppler best signal with high signal to noise ratio in the range of 20-40 dB. The reason why the Doppler beat signal is obtained from a photodiode accommodated in the SM-LD having such a long fiber is attributed to the coherence length enhancement of the SM-LD, which extends to 400 m or more.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Is there a core neuropsychiatric phenotype in 22q11.2 deletion syndrome? (2012)

If a core neuropsychiatric phenotype does exist in 22q11DS, its detection is likely to require dimensional assessment of subtle aspects of cognitive and emotional processing, not encompassed by current diagnostic systems. A core phenotype would account for disruptions across multiple symptom domains, directly reflecting genetic and neurobiological mechanisms. Relative severity of a core phenotype would predict risk for multiple psychiatric disorders, and could, therefore, be an important target for therapeutic and preventive interventions. A core phenotype meeting these criteria has not yet been defined for 22q11DS.
(The Futility of) Data Privacy in Content-Centric Networking (2016)

Content-centric networking is an architecture designed to transfer named and addressable data from producers to consumers. Data retrieval is driven by a simple request and response protocol. A consumer issues a request for named data that is routed by the network towards the nearest location where this data is stored. Once found, the corresponding data is returned to the consumer. This data-centric model is different from the datagram- and stream-based protocols used to transport data between endpoints in IP networks: Instead of being tied to the channel through which data flows, security and privacy properties apply to data itself. Consequently, privacy issues in CCN warrant careful evaluation. In this paper, we present a comprehensive assessment of CCN privacy issues in the presence of various adversaries. We specify conditions sufficient to achieve different levels of privacy. We also show that data privacy is more dependent on requests than responses for data. We conclude that strong privacy necessitates some form of session- or channel-based communication, which strongly contradicts the data-centric nature of CCN. We also discuss how to implement proposed CCN privacy mechanisms in practice.
THE REACTION OF ACETOPHENONE WITH FORMALDEHYDE AND METHYLAMINE HYDROCHLORIDE (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE REACTION OF ACETOPHENONE WITH FORMALDEHYDE AND METHYLAMINE HYDROCHLORIDEJOHN T. PLATI and WILHELM WENNERCite this: J. Org. Chem. 1949, 14, 4, 543–549Publication Date (Print):July 1, 1949Publication History Published online1 May 2002Published inissue 1 July 1949https://pubs.acs.org/doi/10.1021/jo01156a007https://doi.org/10.1021/jo01156a007research-articleACS PublicationsRequest reuse permissionsArticle Views876Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Why predictive indexes perform less well in validation studies. Is it magic or methods? (1987)

• When prognostic indexes have been tested in a second population, they have often performed less well. Since this is believed to be inevitable, methodologic differences that may explain the discrepancies have been overlooked. Data from a prospective study of 232 patients undergoing noncardiac surgery were used to examine the effect of methodologic differences in assembly of population, postoperative surveillance, and the criteria for cardiac complications on the performance of Goldman's cardiac risk index. Our prospective population was used to simulate the methods used in Goldman's study and in three other studies using the risk index to demonstrate the potential impact of differences in population, surveillance, and outcome criteria for cardiac complications. If Goldman's detection and outcome criteria were employed and only the eligibility criteria used for assembly of the populations differed, the overall complication rates would be between 5.2% and 6.9%; and the complication rates for the different Goldman classes were similar. When both different detection strategies and different outcome criteria were used, however, important discrepancies in cardiac complication rates emerged. For example, complication rates in class 2 varied from 2% to 23%. In conclusion, important discrepancies in performance of prognostic indexes may arise from differences in surveillance strategies and definitions of outcome. With sufficient attention to methodologic consistency, the performance of predictive indexes may not inevitably deteriorate in subsequent studies. (<i>Arch Intern Med</i>1987;147:2155-2161)
Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the antiphospholipid syndrome (2004)

Annexin A5 (A5) forms 2-dimensional crystals over phospholipid bilayers, blocking their availability for coagulation reactions. Recently, human antiphospholipid (aPL) monoclonal antibodies (mAbs) have been demonstrated by atomic force microscopy (AFM) to disrupt this crystallization and accelerate coagulation. We therefore performed a study with small, well-defined groups of patients to investigate whether these effects on A5 binding and activity are also detectable in plasmas from patients with the aPL syndrome. A5 binding to phospholipid was significantly reduced by plasmas of patients with the aPL syndrome and thromboembolism compared with healthy controls (mean +/- SD, 26.7 +/- 4.3 ng/well [n = 25] vs 30.5 +/- 3.1 ng/well [n = 20], P < .01) and the non-aPL thromboembolism group (29.9 +/- 3.2 ng/well [n = 15], P < .05). A5 anticoagulant activity was reduced by plasmas of patients with aPL syndrome and thromboembolism compared with aPL antibodies without thrombosis (182 +/- 31% [n = 25] vs 210 +/- 35% [n = 26], P < .01), non-aPL thromboembolism (229 +/- 16% [n = 15], P < .001), and healthy controls (231 +/- 14% [n = 30], P < .001). In conclusion, in accordance with recent AFM data with monoclonal human aPL antibodies, plasmas from patients with aPL antibodies with thromboembolism reduce both A5 binding to phospholipid and A5 anticoagulant activity. This "annexin A5 resistance" identifies a novel mechanism for thrombosis in the aPL syndrome.
Application of phagemid-AAV vector in gene therapy of paediatric brain cancer (2018)

Medulloblastoma and Diffuse intrinsic pontine glioma (DIPG) are childhood brain tumours with high malignancy, the former being the most common and the latter is the most aggressive. Although medulloblastoma patients have a high likelihood of long-term survival after conventional treatment, the prognosis is unfavourable and the treatment options result in long-term neurologic side effects. On the other hand, DIPG patients have a poor survival rate of only 6-10% beyond two years with no effective therapies. Thus, the development of novel, safer and effective therapeutic strategies, or improvement of existing treatments are urgently needed. Gene therapy is an attractive field for the treatment of cancer and offers potential to overcome the limitations of current therapeutic strategies. Here we applied a targeted cytokine gene therapy by using an engineered hybrid adeno-associated phagemid-based vector (PAAV) to selectively target the tumour through cancer-selective integrin binding ligand. PAAV bacteriophage is genetically engineered to express the RGD4C peptide on the vector capsid to ensure targeting of tumour cells and tumour vasculature through binding to α_v β_3 integrin receptor that is overexpressed in tumours and absent or barely detectable in the healthy tissues. In this study, we investigated the efficacy of this targeted vector (RGD4C/PAAV) as a gene delivery vehicle for medulloblastoma and DIPG. The tumour necrosis factor (TNFα) was used as the cytokine therapeutic gene to be delivered and expressed in the tumour cells. This prototype (RGD4C/PAAV-TNFα) induced cell death and activated the caspase pathway in DIPG. This targeted delivery of TNFα was also investigated in medulloblastoma cells in vitro, using UW228 and Daoy medulloblastoma cell lines, and showed high efficacy in inducing cell death. This effect was further augmented by using low dose cisplatin. Moreover, we showed that cisplatin induced the activity of GRP78 and CMV promoters and boosted transgene expression by RGD4C/PAAV in both medulloblastoma and DIPG cells. Finally, the efficacy of our prototype was tested for the treatment of medulloblastoma in vivo through intravenous administration. RGD4C/PAAV- TNFα showed high a and selective tumour homing resulting in targeted TNFα transgene delivery to the tumours. Beside the induction of tumour cell death, this treatment strategy induced damage to the tumour-associated blood vessels, in vivo. TNFα cytokine has long been known to possess anti-tumour activity but also has high systemic toxicity limiting its use in the clinic. In this thesis, we demonstrated that the use of RGD4C/PAAV provides a solution to this problem by targeting TNFα expression selectively to the tumour environment, ensuring systemic safety and therapeutic efficacy for the treatment of childhood brain tumours.
[CT-guided stereotactic biopsies and treatment for deep-seated brain lesions]. (1993)

We performed success fully CT-guided stereotactic biopsies in 21 patients with deep-seated lesions of brain. At the time of biopsy, evacuations and drainages of cystic tumours and grafts of embryo brain tissue into basal ganglion area were practiced. It is suggested that CT-guided stereotactic biopsy should be done in those patients who are of clinical diagnosis, whose lesions in important functional area and who had poor prognosis of operation or who are tolerance to craniotomy. The tissue of brain lesion can be obtained to define diagnosis, direct treatment and evaluate prognosis. Some measures of the treatment can be taken at the time of biopsy.
Microtubule Disassembly by ATP-Dependent Oligomerization of the AAA Enzyme Katanin (1999)

Katanin, a member of the AAA adenosine triphosphatase (ATPase) superfamily, uses nucleotide hydrolysis energy to sever and disassemble microtubules. Many AAA enzymes disassemble stable protein-protein complexes, but their mechanisms are not well understood. A fluorescence resonance energy transfer assay demonstrated that the p60 subunit of katanin oligomerized in an adenosine triphosphate (ATP)- and microtubule-dependent manner. Oligomerization increased the affinity of katanin for microtubules and stimulated its ATPase activity. After hydrolysis of ATP, microtubule-bound katanin oligomers disassembled microtubules and then dissociated into free katanin monomers. Coupling a nucleotide-dependent oligomerization cycle to the disassembly of a target protein complex may be a general feature of ATP-hydrolyzing AAA domains.
[Relationship between the bone marrow cell proliferation and the prognosis in childhood acute lymphoblastic leukemia]. (1999)

The proliferation, LI of leukemic cells was higher than that of normal cells, and reduced to normal level after treatment. The higher PCNA proliferation of untreated cells was a favourable marker for prognosis.
Cellular fluxes of vitamin B12 (1977)

Abstract Incorporation of vitamin B12 into L1210 cells requires the protein binder transcobalamin II (TCII). The process is saturable, follows Michaelis-Menten kinetics (Km = 2.5 X 10(-9) M at 37 degrees C), is both temperature and calcium (K50 - 1 X 10(-6) M) dependent, and is inhibited by apo-TCII, indicating the presence of a TCII specific receptor on the cell membrane. B12 also leaves the cell by a calcium- independent pathway bound to either TCII or to a protein with chromatographic properties similar to those of TCIII. Since intact TCII- B12 can be found in the cytosol and can promote B12 uptake by mitochondria, it is proposed that the B12 released from the cell bound to the TCIII-like protein is derived by mitochondrial processing of incorporated TCII-B12. The slower time course of release of the latter B12 is consistent with this postulate.
Indexing and compressing full-text databases for CD-ROM (1991)

CD-ROM is an attractive delivery velucle for full-text databases. Because of large storage capacity and low access speed, carefully designed indexing structures—including a con cordance—are necessary to enable the text to be retneved efficiently. However, the indexes are sufficiently large that they tax the ability of main store to hold them when processing quenes. The use of compression techniques can substantially mcrease the volume of text that a disk can accommodate, and substantially decrease the amount of pnmary storage needed to hold the indexes. This paper describes a suitable indexing mechanism, and its compression potential using modem compression methods. It is possible to double the amount of text that can be stored on a CD-ROM disk and include a full concordance and indexes as well. A single disk can accommodate around 180 million words of text—equivalent to a library of 1000-1500 books—and provide rapid response to a vanety of quenes involving multi ple search terms and word fragments.
Neurotherapy and Neurofeedback: Brain-Based Treatment for Psychological and Behavioral Problems (2013)

Foreword Allen E. Ivey 1. Introduction to Neurotherapy and Neurofeedback 2. The History of Neurotherapy 3. Sources of Brain Dysregulation 4. The Neurophysiology of Self-Regulation 5. Strategies for Self-Regulation 6. Basic Concepts and Principles in Neurofeedback 7. Assessment, Treatment Planning and Outcome Evaluation 8. Neurofeedback Training, Protocols and Case Studies 9. Neurofeedback Efficacy Research 10. The Future of Neurotherapy and Other Professional Issues References Index
Determination of the sequence distribution and ionization constant of poly(acrylic acid‐co‐vinylamine) by C‐13 NMR (1986)

Abstract Three copolymers of poly(acrylic acid‐co‐vinylamine) containing 12% (SP12). 30% (SP30), and 52% (SP52) amino groups were synthesized from poly(acrylic acid) by means of the Schmidt reaction. These copolymers were analyzed by C‐13 NMR and the results compared wiih the previously analyzed homopolymers. The various comonomer sequence distributions were identified by means of peak areas. It was determined thai (1) the reactivity was not significantly influenced by the triad taciicity of the parent poly(acrylic acid), (2) the final copolymer is characterized by an essentially alternating sequence, and (3) there is extensive lactam formation between neighboring carboxyl and amino groups. In terms of nearest neighbor effects, the relative rales of amine formation are k 1 / k 0 ≈ 0.3 and k 2 / k 0 ≈ 0. A C‐13 NMR pH titration of SPI2 showed that the carboxyl group with a neighboring amino group is more acidic man a carboxyl group flanked by two carboxyl groups.