gebhart/patrepeval huggingface dataset:
Structures of sialylated fucosyl polylactosaminoglycans isolated from chronic myelogenous leukemia cells. (1985)

Polylactosaminoglycans were isolated from human chronic myelogenous leukemia cells and their structures were elucidated. The lactosaminoglycan saccharides were isolated by hydrazinolysis and fractionated by QAE-Sephadex. The structures of fractionated oligosaccharides were analyzed by fast atom bombardment-mass spectrometry and methylation before and after treatment with specific exoglycosidases, such as alpha 2----3 specific neuraminidase. Based on these experiments, the structures of sialyl polylactosaminoglycans of chronic myelogenous leukemia cells were found to contain the following unique structure which is absent in normal mature granulocytes: (formula; see text) In addition to this, chronic myelogenous leukemia polylactosaminoglycans can be distinguished from normal granulocyte polylactosaminoglycans by the following characteristics. Leukemic polylactosaminoglycans are (a) shorter, (b) more highly sialylated and contain fully sialylated, tetrasialosyl polylactosaminoglycans, (c) are less fucosylated at C-3 of N-acetylglucosamine of polylactosaminyl side chains, and (d) contain a significant amount of sialyl Lex, NeuNAc alpha 2----3Gal beta 1----4(Fuc alpha 1----3)GlcNAc beta 1----3, structure. These results indicate that chronic myelogenous leukemia cells express unique polylactosaminoglycan structures which are distinct from normal mature granulocytes.
Two-liquid-phase extractive distillation for upgrading the octane number of the catalytically cracked gasoline (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTwo-liquid-phase extractive distillation for upgrading the octane number of the catalytically cracked gasolineFu Ming Lee and Daniel M. CoombsCite this: Ind. Eng. Chem. Res. 1988, 27, 1, 118–123Publication Date (Print):January 1, 1988Publication History Published online1 May 2002Published inissue 1 January 1988https://pubs.acs.org/doi/10.1021/ie00073a022https://doi.org/10.1021/ie00073a022research-articleACS PublicationsRequest reuse permissionsArticle Views95Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts (2016)

Leucine-rich repeat kinase 2 (LRRK2) is a large, multidomain protein containing two catalytic domains: a Ras of complex proteins (Roc) G-domain and a kinase domain. Mutations associated with familial and sporadic Parkinson's disease (PD) have been identified in both catalytic domains, as well as in several of its multiple putative regulatory domains. Several of these mutations have been linked to increased kinase activity. Despite the role of LRRK2 in the pathogenesis of PD, little is known about its overall architecture and how PD-linked mutations alter its function and enzymatic activities. Here, we have modeled the 3D structure of dimeric, full-length LRRK2 by combining domain-based homology models with multiple experimental constraints provided by chemical cross-linking combined with mass spectrometry, negative-stain EM, and small-angle X-ray scattering. Our model reveals dimeric LRRK2 has a compact overall architecture with a tight, multidomain organization. Close contacts between the N-terminal ankyrin and C-terminal WD40 domains, and their proximity-together with the LRR domain-to the kinase domain suggest an intramolecular mechanism for LRRK2 kinase activity regulation. Overall, our studies provide, to our knowledge, the first structural framework for understanding the role of the different domains of full-length LRRK2 in the pathogenesis of PD.
Combining force and visual feedback for physical interaction tasks in humanoid robots (2009)

In this paper we present a framework for combining force and visual feedback in the task space to deal with humanoid interaction tasks like open doors in a real kitchen environment. We present stereo-vision methods for markerless recognition and estimation of environmetal elements for applying force control strategies for compliant execution using a 6D force-torque sensor mounted in the humanoids's wrist. The framework consists of components for model-based self-localization, visual planning, door recognition, grasping based on visual servoing, real time handle tracking and task execution considering force feedback during the physical interaction with the environment. Experimental results on the humanoid robot ARMAR-IIIa are presented.
COFI RANK - Maximum margin matrix factorization for collaborative ranking (2015)

http://books.nips.cc/papers/files/nips20/NIPS2007_0612.pdf
Angle-dependent photovoltaic effect in Al–Si multilayers (2005)

Al–Si multilayer stacks have been prepared by an alloying process from aluminum and silicon platelets. Irradiation of a stack with infrared to visible laser radiation generates photovoltaic signals depending on the angle of incidence of the laser beam with respect to the layer planes, with zero signal and a polarity reversal for beam and layers in parallel. Results are explained in terms of photoactive layers connected in series and symmetrically aligned along the stack axis. For light beams inclined with respect to the layer planes, asymmetry is introduced by fractional shadowing of photoactive regions due to the intransparent metallic layers.
Keratoprosthesis: preliminary results of an artificial corneal button as a full‐thickness implant in the rabbit model (1996)

Full-thickness implantation of an artificial cornea, analogous to penetrating keratoplasty, has been achieved in the rabbit model. Histological findings confirm that integration of the prosthesis with host tissue occurs. The main complications encountered in this preliminary series were related to inadequate strength of the sponge skirt of this prototype device. Work in our laboratories is now concentrated upon improving the mechanical qualities of the hydrogel skirt and on the enhancement of biointegration.
Self-organizing and learning control systems. (1968)

Self organizing and learning control systems, adaptive systems theory and defining self organizing control systems
Sulfonic-Type Cation-Exchange Resins as Desiccants (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSulfonic-Type Cation-Exchange Resins as DesiccantsC. E. WymoreCite this: Ind. Eng. Chem. Prod. Res. Dev. 1962, 1, 3, 173–178Publication Date (Print):September 1, 1962Publication History Published online1 May 2002Published inissue 1 September 1962https://doi.org/10.1021/i360003a008RIGHTS & PERMISSIONSArticle Views200Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (598 KB) Get e-Alerts
A new personal badge monitor for organic vapors (1980)

A new passive monitor for organic vapors has been developed for the determination of the time-weighted average (TWA) concentration of contaminants in air. This personal dosimeter type badge monitor collects the organic vapors through the mechanism of molecular diffusion and adsorption onto an activated carbon collection element. After exposure, the activated carbon is removed from the device and analyzed using gas chromatographic techniques outlined in NIOSH Physical and Chemical Analysis Method (P&CAM) 127. Current NIOSH standards for measuring the concentration of organic vapors in the atmosphere involve the use of charcoal tubes and sampling pumps for collection, desorption by carbon disulfide and subsequent analysis using gas chromatographic techniques. In comparative testing, the new passive monitor has demonstrated that its overall accuracy is at least equivalent to the charcoal tube method in determining ambient contaminant concentration. Several organic compounds were sampled over the range of 0.5 ppm - 1100 ppm exposure levels. Both field and laboratory tests were conducted and the results were compared. Environmental parameters such as temperature, relative humidity, and air movement were among the factors examined. Other factors considered were desorption efficiencies, sampling rates, sampling range, bias, and precision.
TUBULAR LINEAR INDUCTION MACHINE AS A FAST ACTUATOR: ANALYSIS AND DESIGN CRITERIA (2012)

In this paper, some design criteria for a Tubular Linear Induction Motor (TLIM) as a fast actuator are considered. The influence of geometrical and physical parameters on the operating conditions of a TLIM are investigated by means a quasi-analytic model. The model is based on the application of the Fourier Transform both in space and in time. The Fourier transform in space is introduced to take into account the finite length of the stator windings in the axial direction. The transient electrical response of the motor at standstill following the insertion of a three-phase system of voltage generators is performed by the Fourier transform in the time.
The WASP: an atonomous surface vessel for the University of Alaska (2005)

The vision of the autonomous surface vessel program is to develop an instrumented boat capable of robust, automatic sampling of oceanographic data at specific locations and depths in estuary and coastal waters. The objective of the WASP project was to develop an initial prototype of such a system including software, physical hardware and electronic components. The physical structure includes pontoons, vertical supports, and a platform housing the vessel's power source, onboard electronics and payload. The onboard electronics control the movement and functionality of the vessel and the payload of scientific instruments are attached to a winch for taking readings at depth. Also, the user interface developed for the wireless communication and control of the vessel is Internet based allowing the user to control the vessel anywhere in the world. This prototype will be integrated and tested in Elkhorn Slough during the summer of 2005 as part of an SCU-MBARI project. The work performed to date has been critical in the development of the ASV concept which is expected to lead to an operational system deployed in the Kasitsna Bay Laboratory in Alaska and other national estuaries.
3D object recognition using a mobile laser range finder (2002)

Presents a 3D object recognition system with emphasis on an optimum placement strategy for a mobile 3D range sensor. The theoretical aspects leading to the development of the 3D sensor placement paradigm are presented and described. The authors use a triangulation type laser of range finder in which a CCD based imaging device is utilized to view a plane of laser light bounced from a sweeping mirror. The sensor characteristics are described and modeled. A set of criteria for use in constraining the possible sensor site location for future scans is presented. These constraint conditions are essential to drive the actual sensor placement algorithm for 3D object recognition.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Assessment of Bacterial Contamination of Raw Meats Sold in Korea, 2007 (2007)

본 연구는 인간의 건강과 식품의 오염을 예방하기 위한 유용한 자료를 얻기 위하여 육류(소고기, 닭고기, 돼지고기)로부터 분리된 staphylococci를 가지고 한국에서 광범위하게 사용되는 6가지 항생제와 daptomycin, linezolid, quinupristin/dalfopristin and tigecycline과 같은 4가지의 신항생제에 대한 항생제 감수성 시험을 수행하였다. 이에 더하여 육류의 세균 오염실태를 조사하기 위하여 총 세균수와 대장균수를 측정하였다. 그 결과 147개의 육류 샘플 중 48%의 샘플에서 일반세균수의 기준에 부적합한 결과가 나타났으며, 대장균수에 대해서는 31%의 샘플에서 기준에 부적합한 결과가 나타났다. 또한 육류의 91%에서 stapylococci가 검출되었으며 이들 staphylococci는 Coagulase Negative Staphylococci(CNS)와 S. aureus로 동정되었다. 분리된 staphylococci의 5.4%가 methicillin (oxacillin)에 내성을 나타내었고, 특히 mupirocin (MIC??, ＞ 12㎍/mL)과 gentamicin (MIC??, 64㎍/mL)에 높은 내성을 나타내었다. 그러나 신항생제에 대해서는 methicillin 내성 staphylococci를 포함한 모든 staphylococci 분리균주가 높은 감수성을 나타내었다. 결론적으로 본 연구의 결과들은 육류가 소비자들의 건강에 중요한 위험요소로 작용할 수 있음을 보여주고 있다.
Highly Ordered Monolayer, Multilayer, and Hybrid Films of Graphene Oxide Obtained by the Bubble Deposition Method (2011)

Graphene oxide (GO) is a promising candidate for many applications ranging from electronics to sensors. The properties of graphene-based materials not only are dependent on the quality of the sheets but are largely influenced by the way they are assembled. Many techniques have traditionally been used to form GO films, but each of them presents some drawbacks. Herein, we report the use of the original bubble deposition method (BDM) as a simple and powerful method to precisely order and deposit GO films on arbitrary substrates. The intrinsic drainage parameter can be simply adjusted to deposit monolayer films from quasi-isolated flakes to high surface coverage. The flexibility of this method allows the formation of thickness-controlled GO films with negligible interlayer spacing, as well as hybrid materials made of GO sheets and carbon nanotubes.
An update on Chagas disease (human American trypanosomiasis) (2006)

Human American trypanosomiasis or Chagas disease -- named after Carlos Chagas who first described it in 1909 -- exists only on the American continent. It is caused by a parasite, Trypanosoma cruzi, that is transmitted to humans by blood-sucking triatomine bugs, by blood transfusion, and transplacentally. Chagas disease has two, successive phases: acute and chronic. The acute phase lasts 6-8 weeks. After several years of starting the chronic phase, 20%-35% of infected individuals (the percentage varying with geographical area) develop irreversible lesions of the autonomous nervous system in the heart, the oesophagus, the colon and/or the peripheral nervous system. Data on the prevalence and distribution of Chagas disease markedly improved in quality during the 1980s, as a result of demographically representative, cross-sectional studies carried out in countries where no accurate information on these parameters was available. Experts had previously met in Brasilia, in 1979, and devised standard protocols for carrying out country-wide studies not only on the prevalence of human infection with T. cruzi but also on house infestation with the triatomine vectors. Thanks to a co-ordinated programme in the southernmost countries of South America (i.e.the 'Southern Cone'), transmission of T. cruzi by the vectors or blood transfusion has been successfully interrupted in Uruguay (from 1997), Chile (from 1999) and Brazil (from 2005), and the global incidence of new human infection with T. cruzi has decreased by 67%. Similar multi-country control initiatives have been launched in the Andean countries and in Central America, with the goal of interrupting all transmission of T. cruzi to humans by 2010 -- a goal set, in 1998, as a resolution of the World Health Assembly. Recent advances in basic research on T. cruzi include the genetic characterization of populations of the parasite and the sequencing of its genome.
A Brief Questionnaire to Screen for Quality of Life in Epilepsy The QOLIE‐10 (1996)

The QOLIE-10 can be completed by a patient in several minutes and reviewed rapidly by the physician. This screening tool could provide potentially useful information for initial assessment or follow-up of problem areas that are not commonly evaluated during routine clinical visits with patients with epilepsy.
Optical characterization of a complex grating profile (1998)

Abstract The grating studied here, produced by interferographic exposure of photoresist, comprises two gratings, one with twice the period of the other, aligned so that their Bragg vectors are separated by an angle of 0.02°. Thus, as one moves along the grooves, these two gratings locally vary their relative phase. Coating this grating with metal allows the optical characterization of this surface by the excitation of surface plasmon polaritons. This paper starts by demonstrating the inability of a profilometer to profile accurately the surface of this bi-grating because of the limitations imposed by the finite width of the stylus on the scale of the grating grooves. Angle-dependent reflectivity data are then used to characterize the metal-coated surface. The size and shape of the surface plasmon resonances in these data, once matched to a rigorous theoretical model, are shown to provide a quantification of the surface profile. This accords with both the profile expected from the limited profilometer study, and more significantly with the surface function predicted using a simple model of the photoresist's response to exposure.
Lithiated MoO<sub>3</sub> Nanobelts with Greatly Improved Performance for Lithium Batteries (2007)

α-MoO3 nanobelts are successfully lithiated by a secondary reaction. The capacity retention rate of lithiated MoO3 nanobelts is 92 % after 15 cycles, whereas the non-lithiated nanobelts retain only 60 % (see figure). The conductivity is increased by close to two orders of magnitudes after lithiation suggesting that Li+ ions have been introduced into the MoO3 layers during lithiation. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c0883_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
C-Reactive Protein (CRP) Is Essential for Efficient Systemic Transduction of Recombinant Adeno-Associated Virus Vector 1 (rAAV-1) and rAAV-6 in Mice (2013)

The clinical relevance of gene therapy using the recombinant adeno-associated virus (rAAV) vectors often requires widespread distribution of the vector, and in this case, systemic delivery is the optimal route of administration. Humoral blood factors, such as antibodies or complement, are the first barriers met by the vectors administered systemically. We have found that other blood proteins, galectin 3 binding protein (G3BP) and C-reactive protein (CRP), can interact with different AAV serotypes in a species-specific manner. While interactions of rAAV vectors with G3BP, antibodies, or complement lead to a decrease in vector efficacy, systemic transduction of the CRP-deficient mouse and its respective control clearly established that binding to mouse CRP (mCRP) boosts rAAV vector 1 (rAAV-1) and rAAV-6 transduction efficiency in skeletal muscles over 10 times. Notably, the high efficacy of rAAV-6 in CRP-deficient mice can be restored by reconstitution of the CRP-deficient mouse with mCRP. Human CRP (hCRP) does not interact with either rAAV-1 or rAAV-6, and, consequently, the high efficiency of mCRP-mediated muscle transduction by these serotypes in mice cannot be translated to humans. No interaction of mCRP or hCRP was observed with rAAV-8 and rAAV-9. We show, for the first time, that serum components can significantly enhance rAAV-mediated tissue transduction in a serotype- and species-specific manner. Bioprocessing in body fluids should be considered when transfer of a preclinical proof of concept for AAV-based gene therapy to humans is planned.
Vitrification and devitrification of the rigid amorphous fraction in poly(ethylene terephthalate) (2009)

Abstract Vitrification and devitrification of the rigid amorphous fraction (RAF) of poly(ethylene terephthalate) (PET), analyzed during development and disappearance of the three phase structure, are detailed in this contribution. Upon cooling from the melt at a constant rate, the rigid amorphous fraction starts to vitrify when the crystallization process is almost finished, and continues on further cooling. The rigid amorphous fraction is formed in the same temperature range of the secondary crystal growth. Analysis of the low melting endotherm that is observed in isothermally crystallized PET a few degrees above the crystallization temperature reveals a joint contribution of melting and devitrification of the rigid amorphous fraction. The results confirm a link between secondary crystallization and vitrification of the rigid amorphous fraction in semicrystalline polymers. Secondary crystallization takes place in geometrically restricted areas, in which the polymer chains undergo large constraints, so that the mobility of the amorphous chain portions coupled with the crystal phase is reduced. Similarly, the gain in mobility upon partial melting of thinner and/or more defective crystals allows an increase in mobility of the coupled amorphous regions, which results in concurrent mobilization of the rigid amorphous fraction.
Grass seed yields increased with plant growth regulators and fungicides (2004)

Seed yields of ryegrass and tall fescue have increased rapidly over the last seven years; the best farm yields are now reaching 3000 kg/ha, up from 2000 kg/ha. These increases are largely due to the adoption of technologies developed from research funded from grower crop levies and effective technology transfer programmes. The key technologies are (1) the adoption of trinexapac ethyl (TE), a plant growth regulator that blocks gibberellic acid biosynthesis and reduces lodging; and (2) new generation triazole and strobilurin fungicides that give improved disease control and extend the period that green leaf area is maintained on crops. Seed yield data from 10 ryegrass and 6 tall fescue trials with TE, and from 13 fungicide trials are presented. The average seed yield increase in tall fescue treated with 200 g TE/ha and ryegrass with 400 g TE/ha was 67% and 50% respectively. In fungicide trials, seed yields in forage perennial ryegrass were increased by 20% and in turf ryegrass by 42%. A survey of growers indicated 95% of ryegrass growers and 100% of tall fescue growers had adopted the use of TE three years after the commercial release of the product. Keywords: fungicides, plant growth regulators, ryegrass, seed yield, strobilurin, tall fescue, triazole, trinexapac
Use of Cigarette-Smoking History to Estimate the Likelihood of Mutations in Epidermal Growth Factor Receptor Gene Exons 19 and 21 in Lung Adenocarcinomas (2006)

The likelihood of EGFR mutations in exons 19 and 21 decreases as the number of pack-years increases. Mutations were less common in people who smoked for more than 15 pack-years or who stopped smoking cigarettes less than 25 years ago. These data can assist clinicians in assessing the likelihood of exon 19 and 21 EGFR mutations in patients with lung adenocarcinoma when mutational analysis is not feasible.