gebhart/patrepeval huggingface dataset:
Vapor-Liquid Separation at Supersonic Velocities (1968)

When a gas mixture at high pressure is expanded to a lower pressure, autorefrigeration often causes some of the heavier components to liquefy. This paper presents a new method for separating components of a gas stream by incorporating isentropic expansion and subsequent inertial separation of the dispersed liquid phase formed. Supersonic velocity of the stream is attained upon expansion and is maintained during the vapor-liquid separation process. Liquid droplets are ejected through the permeable outer wall of a curved flow channel, effecting the phase separation. Pressure is recoverable in part, if the supersonic stream is decelerated in a diffuser after removal of the liquid phase. Design considerations of such a process and major parameters for obtaining and maintaining stable supersonic channel flow are discussed. An experimental unit designed for an 1800 psi natural gas feed stream has been tested and preliminary results are summarized.
Visceral nociception and pain (2005)

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Polymerization Process Modeling (1995)

Nomenclature distinctive features of polymers and polymerization step growth polymerization chain growth polymerization copolymerization non-linear polymerization reactor polymerization reactor configuration heterogenous polymerization.
Roles of Metal Ions in the Formation of Hematite Particles from Forced Hydrolysis Reaction (2000)

The roles of metal (Me) ions (Cu(II) and Cr(III)) in the morphologies and structures of hematite particles, produced from a forced hydrolysis reaction of FeCl3−HCl at various concentrations of metal ions ranging from 0 to 0.8 in the Me/(Fe + Me) atomic ratio (XMe), were investigated by separation of the reaction into two steps: precipitation of β-FeOOH and phase transformation from β-FeOOH to hematite. The metal ions inhibited the particle growth of β-FeOOH at a lower concentration region, while they promoted the particle growth at a higher concentration region with incorporation of these ions into the crystal lattice. The β-FeOOH particles produced with metal ions exhibited high specific surface areas and microporosities. It was suggested that the phase transformation from β-FeOOH to hematite is strongly affected by the metal ions incorporated into β-FeOOH particles but not by those adsorbed on the particle surface.
Effects of <i>galU</i> Mutation on <i>Pseudomonas syringae</i>–Plant Interactions (2010)

Bacterial galU coding for a uridine diphosphate-glucose pyrophosphorylase plays an important role in carbohydrates biosynthesis, including synthesis of lipopolysaccharides (LPS), membrane-derived oligosaccharides, and capsular polysaccharides. In this study, we characterized the galU mutant of Pseudomonas syringae pv. syringae 61 (Psy61), a necrotizing plant pathogen whose pathogenicity depends on a functional type III secretion system (T3SS), and showed that the Psy61 galU mutant had reduced biofilm formation ability, was nonmotile, and had an assembled T3SS structure but failed to elicit hypersensitive response in resistant plants and necrotic lesions in susceptible plants. Moreover, the defective LPS and other pathogen-associated molecular patterns (PAMPs) on the surface of the Psy61 galU mutant were capable of inducing PAMP-triggered immunity, which severely compromised the ability of the Psy61 galU mutant to survive in planta. Our results demonstrated that the complete LPS protected plant-pathogenic bacteria from host innate immunity, similar to what was found in animal pathogens, prior to the translocation of T3S effectors and bacterial multiplication.
Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD (2008)

The role of the marrow microenvironment in the pathophysiology of myelodysplastic syndromes (MDSs) remains controversial. Using stromal/hematopoietic cell cocultures, we investigated the effects of stroma-derived signals on apoptosis sensitivity in hematopoietic precursors. The leukemia-derived cell line KG1a is resistant to proapoptotic ligands. However, when cocultured with the human stromal cell line HS5 (derived from normal marrow) and exposed to tumor necrosis factor-alpha (TNF-alpha), KG1a cells showed caspase-3 activation and induction of apoptosis. Apoptosis was contact dependent. Identical results were obtained in coculture with primary stroma. Gene-expression profiling of KG1a cells identified coculture-induced up-regulation of various genes involved in apoptosis, including PYCARD. Suppression of PYCARD expression in KG1a by miRNA interfered with apoptosis. Knockdown of the TNF receptor 1 (TNFR1) or TNFR2 in HS5 cells had no effect. However, knockdown of R1 in KG1a cells prevented TNF-alpha-induced apoptosis, while apoptosis was still induced by TNF-alpha-related apoptosis-inducing ligand. Primary CD34(+) cells from MDS marrow, when cocultured with HS5 and TNF-alpha, also underwent apoptosis. In contrast, no apoptosis was observed in CD34(+) cells from the marrow of healthy donors. These data indicate that stroma may convey not only protective effects on hematopoietic cells, but, dependent upon the milieu, may also facilitate apoptosis.
Utilization of Two Distinct Modes of Replication by a Hybrid Plasmid Constructed <i>In Vitro</i> from Separate Replicons (1974)

A hybrid plasmid, pSC134, that codes for two distinct sets of replication functions has been constructed in vitro by ligation of EcoRI endonuclease-cleaved pSC101 and Col E1 plasmid replicons, and has been introduced into Escherichia coli by transformation. The replication properties of the pSC134 plasmid in DNA polymerase I-defective mutants or in the presence of chloramphenicol indicate that this hybrid plasmid can utilize the functionally distinct modes of replication specified by both of its parent replicons.
A high-yield microassembly structure for three-dimensional microelectrode arrays (2000)

This paper presents a practical microassembly process for three-dimensional (3-D) microelectrode arrays for recording and stimulation in the central nervous system (CNS). Orthogonal lead transfers between the micromachined two-dimensional probes and a cortical surface platform are formed by attaching gold beams on the probes to pads on the platform using wire-free ultrasonic bonding. The low-profile (150 microns) outrigger design of the probes allows the bonding of fully assembled high-density arrays. Micromachined assembly tools allow the formation of a full 3-D probe array within 30 min. Arrays having up to 8 x 16 shanks on 200-micron centers have been realized and used to record cortical single units successfully. Active 3-D probe arrays containing on-chip CMOS signal processing circuitry have also been created using the microassembly approach. In addition, a dynamic insertion technique has been explored to allow the implantation of high-density probe arrays into feline cortex at high-speed and with minimal traumatic injury.
Deepwater Multiwell Subsea Production System (1986)

A lack of confidence in manifold systems, flowline connections, production riser capacities, and difficulties with downhole and equipment maintenance have in the past restricted subsea production designs to a limited number of wells. An investigation into these critical areas has enabled solutions to be developed and a detailed preliminary study has been made on a hypothetical field in 3000ft of water with two production horizons. A prototype concept has been developed in the form of a 35-ft well, mostly dual completion, guidelineless, diverless system featuring commingled production from the two horizons through subsea tree, choke, and manifold systems. A semisubmersible Floating Production Vessel is located directly over the central template and connected to it by flexible risers; it can also be used for central template drilling, running, and retrieving most of the subsea equipment, and also for well workover.
High Pressure Synthesis and Magnetostrictive Measurement of Laves Phase Pr<sub>1-x</sub>R<sub>x</sub>Fe<sub>2</sub> (R=Ce, Nd) (1993)

Laves phase rare-earth iron intermetallic compounds were synthesized under high pressure and high temperature by using a double stage multianvil high pressure equipment. The minimum pressure required to synthesize the Laves phase was determined. The maximum magnetostriction of 8×10 -6 was attained at room temperature for PrFe 1.8 .
Demonstration of Convolution Kernel Operation on Resistive Cross-Point Array (2016)

Convolution is the key operation in the convolutional neural network, one of the most popular deep learning algorithms. The implementation of the convolution kernel on the resistive cross-point array is different than the implementation of the matrix-vector multiplication in prior works. In this letter, we propose a dimensional reduction of 2-D kernel matrix into 1-D column vector, i.e., a column of the array, and enable the parallel readout of multiple 2-D kernels simultaneously. As a proof-of-concept demonstration, we use the Prewitt kernels to detect both horizontal and vertical edges of the 20 × 20 pixels of black and-white MNIST handwritten digits. The experiments were performed on the fabricated 12 × 12 resistive cross-point array based on the Pt/HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> /TiN structure. The experimental results of the Prewitt kernel operation perfectly matches the simulation results, indicating the feasibility of the proposed implementation methodology of the convolution kernel on resistive cross-point array.
Chemical modification of erythromycin antibiotics. 4. Structure-activity relations of erythromycin esters (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemical modification of erythromycin antibiotics. 4. Structure-activity relations of erythromycin estersYvonne C. Martin, Peter H. Jones, Thomas J. Perun, Walton E. Grudy, Stanley Bell, Robert R. Bower, and Nathan L. ShipkowitzCite this: J. Med. Chem. 1972, 15, 6, 635–638Publication Date (Print):June 1, 1972Publication History Published online1 May 2002Published inissue 1 June 1972https://pubs.acs.org/doi/10.1021/jm00276a018https://doi.org/10.1021/jm00276a018research-articleACS PublicationsRequest reuse permissionsArticle Views325Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Value of Serial Troponin T Measures for Early and Late Risk Stratification in Patients With Acute Coronary Syndromes (1998)

The cTnT level is a strong, independent predictor of short-term outcome in acute coronary syndromes. The addition of later samples to a baseline level is useful to evaluate the risk of serious cardiac events.
A survey of security challenges in cloud computing (2017)

The cloud is an attractive technology which led, in record time, to an unprecedented fascination. It is currently one of the busiest areas of research in IT, because of its flexibility, robustness and ability to significantly reduce the costs of services to users on the internet. Moreover, cloud stores all customer data in data centers scattered around the world. Therefore, security has become a paramount concern that prevents many companies to adopt its services. Users are supposed to store their data, some of which are typically confidential or personal, therefore, we are very attentive to data integrity and confidentiality during transfer to a cloud server. This research paper aims to develop an analysis on the various security risks involved in cloud computing.
A Steiner tree approach to efficient object detection (2010)

We propose an approach to speeding up object detection, with an emphasis on settings where multiple object classes are being detected. Our method uses a segmentation algorithm to select a small number of image regions on which to run a classifier. Compared to the classical sliding window approach, this results in a significantly smaller number of rectangles examined, and thus significantly faster object detection. Further, in the multiple object class setting, we show that the computational cost of proposing candidate regions can be amortized across objects classes, resulting in an additional speedup. At the heart of our approach is a reduction to a directed Steiner tree optimization problem, which we solve approximately in order to select the segmentation algorithm parameters. The solution gives a small set of segmentation strategies that can be shared across object classes. Compared to the sliding window approach, our method results in two orders of magnitude fewer regions considered, and significant (10-15×) running time speedups on challenging object detection datasets (LabelMe and StreetScenes) while maintaining comparable detection accuracy.
Shooting the messenger: RNA-targetting CRISPR-Cas systems (2018)

Since the discovery of CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats, CRISPR-associated genes) immune systems, astonishing progress has been made on revealing their mechanistic foundations. Due to the immense potential as genome engineering tools, research has mainly focussed on a subset of Cas nucleases that target DNA. In addition, however, distinct types of RNA-targetting CRISPR-Cas systems have been identified. The focus of this review will be on the interference mechanisms of the RNA targetting type III and type VI CRISPR-Cas systems, their biological relevance and their potential for applications.
Protein deposits on individual hydrophilic contact lenses: effects of water and ionicity. (1989)

Chemical procedures have been developed for eluting deposits from individual hydrophilic contact lenses using combinations of solvents. Total protein was determined as a function of the FDA-proposed classification system for hydrogel lenses. Group IV lenses (high water content, ionic matrix polymers) contained the greatest amount of protein deposits, while group I lenses (low water content, non-ionic polymers) contained the least. Group II lenses (high water content, non-ionic polymers) showed an affinity for protein greater than groups I and III (low water content, ionic polymer) but significantly less than group IV. The necessary basic conditions for maximal protein contamination of hydrophilic contact lenses seems to be created through a combination of an ionic polymer existing in a polar, high water content milieu.
Trusted Execution Environments: A Look under the Hood (2014)

Smartphones are now handling personal and extremely important data and applications. This increases mobile environment threats and makes smartphones one of attackers' preferred targets. To mitigate threats, many proposals and counter-measures have been proposed. In this paper, we focus on one of them, the Trusted Execution Environment (TEE) which is a new family of architecture having its own hardware and software environment completely isolated from the mobile ones. It intends to offer better security than the one provided by mobile platforms. It proposes for example secure storage to applications running on top of the mobile Operating System. We give a complete overview of standardization activities on TEE. We first detail the software and hardware architecture of the TEE as introduced by GlobalPlatform specifications. Then, we describe the different available TEE solutions. Finally, we compare these solutions according to key performance parameters with a special interest to security aspects.
Current concepts of the management of dental extractions for patients taking warfarin (2003)

Patients therapeutically anticoagulated with warfarin can be treated on an ambulatory basis, without interruption of their warfarin regimen provided appropriate local measures are used.
Comparison of the 3D-conformal, helical tomotherapy and multileaf collimators-based intensity modulated radiotherapy modalities using radiobiological measures. (2008)

In comparison to 3D conformal radiotherapy, both MLC based-IMRT and HT can better encompass the often large ITV required while minimizing the volume of the organs at risk receiving high dose. Taking into account the dose-response relations of the irradiated tumors and normal tissues, a radiobiological treatment plan evaluation can be performed, which may provide a closer association of the delivered treatment with the clinical outcome.
Magnetic Properties of Lone‐Pair‐Containing, Sandwich‐Type Polyoxoanions: A Detailed Study of the Heteroatomic Effect (2004)

Abstract Magnetic susceptibility and high‐frequency EPR spectroscopy investigations were carried out on the isostructural family of tricopper( II )‐substituted, sandwich‐type polyoxotungstates [Cu 3 (H 2 O) 3 (α‐AsW 9 O 33 ) 2 ] 12− ( 1 ), [Cu 3 (H 2 O) 3 (α‐SbW 9 O 33 ) 2 ] 12− ( 2 ), [Cu 3 (H 2 O) 3 (α‐SeW 9 O 33 ) 2 ] 10− ( 3 ), and [Cu 3 (H 2 O) 3 (α‐TeW 9 O 33 ) 2 ] 10− ( 4 ) with the intention of examining the possible influence of the diamagnetic heteroatoms X (X = As III , Sb III , Se IV , Te IV ) on the magnetic exchange properties of the three Cu 2+ ions in the central belt. Magnetic susceptibility data indicate a single antiferromagnetic spin exchange constant J for the triangular Cu 3 belts in 1 − 4 . Variable‐temperature, W‐band (ca. 94 GHz) EPR spectra reveal that the Cu 3 units have S T = 1/2 as the spin ground state with the excited state S T = 3/2 located within a few cm −1 . We also determined the g matrix components for both the S T = 1/2 and 3/2 states. The zero‐field parameter D has been measured for the S T = 3/2 state, and its sign is shown to be positive for 1 − 4 . From the analysis of the g matrix components for the molecular and the local Cu 2+ site symmetry, the unpaired electrons are shown to occupy the 3d x 2 − y 2 orbitals. The J values change from −1.36 to −1.04 cm −1 for 1 and 2 , and from −1.52 to −1.48 cm −1 for 3 and 4 , respectively. The g values follow a similar trend, but the D value for 4 implies a role of through‐space as well as through‐bond sources for the magnetic interactions in the Cu 3 belt. Our results suggest that the heteroatoms, containing lone pairs, allow the fine tuning of the magnetic parameters of 1 − 4 . (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Polysilicon Integrated Microsystems: Technologies And Applications (2005)

Merging polysilicon microstructures with CMOs electronics offers monolithic solutions for inertial sensing and micromechanical signal processing. Correlations between polysilicon deposition, doping, and anneal conditions and the mechanical properties are understood. A low-thermal impact polysilicon process could be merged with submicron CMOS. In vacuum, the Brownian noise of a polysilicon accelerometer is about 1 /spl mu/g/Hz/sup 1/2/. An integrated sigma-delta controller, implemented in 1 /spl mu/m CMOS, can in principle resolve this noise. Microresonator oscillators and filters are of potential application in low-power electronic signal processing. Building-block approaches to microsystem design are emerging.
How I treat the peripheral T-cell lymphomas (2014)

The peripheral T-cell lymphomas (PTCLs) encompass a heterogeneous group of diseases that have generally been associated with poor prognosis. The most common PTCLs, peripheral T-cell lymphoma, not otherwise specified, angioimmunoblastic T-cell lymphoma, and anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALK-negative), despite their unique presentations and histologies, are currently treated similarly. Here we discuss our general approach to the treatment of the most common PTCLs. Based on the best data currently available, which include retrospective analyses and phase 2 prospective studies, our approach has involved cyclophosphamide, doxorubicin, vincristine, prednisone-based therapy followed by consolidation in first remission with autologous stem cell transplant. This treatment strategy likely improves the outcome for patients compared with historical series; however, progression-free survival rates remain disappointing, ranging from 40% to 50%. This is currently an exciting time in the treatment of PTCL due to the advent of recently approved drugs as well as new targeted agents currently under investigation. In addition, gene expression profiling is allowing for a better understanding of underlying disease biology, improved diagnostic accuracy, and prognostication in PTCL. As a result, over the next few years, we expect a significant shift in our management of these diseases with a move toward more individualized therapy leading to improved outcomes.
SEMINARIO DE REFLEXIONES SOBRE LA PRATICA DEL TRABAJO SOCIAL (1980)

AL INAUGURAR EL SEMINARIO DE REFLEXIONES SOBRE LA PRACTICA DEL TRABAJO EN LA UNIDAD DE SEMINARIOS DOCTOR IGNACIO LA LICENCIADA YOLANDA AGUIRRE HARRIS; DIRECTORA DE LA ESCUELA NACIONAL DE TRABAJO SOCIAL; EXTERNO QUE ESE EVENTO CONSTITUYE SOLO EL PRINCIPIO DE UN PROGRAMA DE FORMACION; SUPERACION Y ACTUALIZACION DOCENTE QUE SE DESARROLLARA EN ESA DEPENDENCIA. AGUIRRE HARRIS DEJO ENTREVER QUE EL TEMA CENTRAL DEL EVENTO ES EL DE LA BASE TEORICA DE LA PRACTICA; DEBIDO A LA IMPORTANCIA QUE TIENE EN EL PLAN DE ESTUDIOS DE LA LICENCIATURA; Y POR LA INQUIETUD QUE TANTO PROFESORES COMO ALUMNOS HAN MANIFESTADO. POR SU PARTE; LA LICENCIADA AIDA VALERO CHAVEZ; CATEDRATICA DE LA CITADA INSTITUCION ACADEMICA; AFIRMO QUE EL PLAN DE ESTUDIOS DE LA LICENCIATURA EN TRABAJO SOCIAL TIENE COMO OBJETIVO FORMAR PROFESIONISTAS QUE SEAN CAPACES DE CUMPLIR CON UN PROCESO DE INVESTIGACION; ORGANIZACION; MOVILIZACION; PLANEACION Y ADMINISTRACION SOCIAL CON EL FIN DE PROFUNDIZAR EN EL CONOCIMIENTO DE DIVERSAS COMUNIDADES; UTILIZANDO LAS TECNICAS DE INVESTIGACION DOCUMENTAL Y DE CAMPO; QUE AYUDEN A COMPRENDER LA SITUACION DE ALGUNA POBLACION EN ESPECIFICO.