gebhart/patrepeval huggingface dataset:
Aggregating resource reservations over multiple routing domains (2002)

Presents an agent-based architecture for resource reservations. For each domain in the network, there is an agent that is responsible for admission control. The architecture provides scalable per-link resource reservations in agents and low per-packet overhead in routers. The key ideas are the following. First, reservations from different sources to the same destination are aggregated as their paths merge toward the destination. Second, an agent in charge of resources at the final destination can generalize reservations for specific end-points so that they are valid for any end-point in the destination domain, thereby allowing more aggregation. Third, agents can do bulk reservations in advance with neighboring agents, thereby allowing aggregation over time. Fourth, agents are responsible for setting up policing points at edge routers for checking commitments. Agents can minimize the per-packet policing overhead in routers by varying the granularity of policing over time.
A Study on Promotional Management Honeypot (2010)

Promotional activities have been commonly used by the retailers to increase profits, but the deficiencies of promotional system have brought about the losses in many aspects, which increasingly becomes the focus of the market's attention. With the introduction to the concept of management honeypot, this paper records management issues and submits them to the administrative levels, and meanwhile figures out the loopholes in the management activities of promotion through incentives. Promotional management honeypot can be carried out during planning, implementation and supervision of promotional activities to achieve the purpose of optimizing the promotional management activities.
Towards Real-Time Audiovisual Speaker Localization (2011)

Publication in the conference proceedings of EUSIPCO, Barcelona, Spain, 2011
Regulation of Niemann-Pick C1 Gene Expression by the 3′5′-Cyclic Adenosine Monophosphate Pathway in Steroidogenic Cells (2003)

The Niemann Pick-C1 (NPC-1) protein is essential for intracellular transport of cholesterol derived from low-density lipoprotein import in mammalian cells. The role of the protein kinase A (PKA) pathway in regulation of expression of the NPC-1 gene was investigated. NPC-1 promoter activity was induced by treatment with dibutryl cAMP (dbcAMP), alone or in combination with the cAMP response element (CRE) binding protein (CREB) overexpressed in adrenal Y-1 cells. When the catalytic subunit of PKA was overexpressed in Y-1 cells, there were similar increases in NPC-1 promoter activity in the presence of CREB. Responses were attenuated by blockade of the PKA pathway, and in the Kin-8 cell line deficient in PKA. Promoter deletion analysis revealed that this response was present in promoter fragments of 186 bp and larger but not present in the 121-bp fragment. Two promoter regions, one at -430 and one at -120 upstream of the translation initiation site, contained CRE consensus sequences. These bound recombinant CREB in EMSA, confirming their authenticity as CREB response elements. Promoters bearing mutations of both CRE displayed no response to dbcAMP. The orphan nuclear receptor, steroidogenic factor-1 (SF-1), was implicated in NPC-1 transactivation by the presence of SF-1 target sequence that formed a complex with recombinant SF-1 in EMSA. Furthermore, transfection of a plasmid that overexpressed SF-1 into ovarian granulosa cells increased promoter activity in response to dbcAMP, an effect abrogated by mutation of the SF-1 target sequence. Chromatin immunoprecipitation assays demonstrated that the CRE region of the endogenous and transfected NPC-1 promoter associated with both acetylated and phosphorylated histone H-3 and that this association was increased by dbcAMP treatment. Treatment with dbcAMP also increased the association of the CRE region of the promoter with CREB binding protein, which has histone acetyltransferase activity. Together, these results demonstrate a mechanism of regulation of NPC-1 expression by the cAMP-PKA pathway that includes PKA phosphorylation of CREB, recruitment of the coactivator CREB binding protein and the phosphorylation and acetylation of histone H-3 to transactivate the NPC-1 promoter.
Einleitung (1952)

In der Lehre von dem Blute und den Blutkrankheiten hat sich in den Jahren, die seit dem ersten Erscheinen dieses Buches verflossen sind, die biologisch-funktionelle Betrachtungsweise weiter durchgesetzt. Diese ist zwar auch heute noch eine vorwiegend morphologische, jedoch hat sich in der Folge der letzten 30 Jahre die Auffassung des Blutes und seiner Bildungsstätten als eines eigenen Gesamtorgans, des Blutorgans, sowie die Erforschung seiner funktioneilen und biologischen Reaktionsweisen unter physiologischen und pathologischen Bedingungen immer mehr gefestigt, während dagegen in den Kinder- und Jünglingsjähren der Hämatologie als einer Spezialwissenschaft die Betrachtung der Einzelzelle und ihrer morphologischen Veränderungen im Vordergrund stand.
The role of eukaryotic subtilisin-like endoproteases for the activation of human immunodeficiency virus glycoproteins in natural host cells (1997)

Proteolytic activation of the precursor envelope glycoproteins gp160 of human immunodeficiency virus type 1 (HIV-1) and gp140 of HIV-2, a prerequisite for viral infection, results in the formation of gp120/gp41 and gp125/gp36, respectively. Cleavage is mediated by cellular proteases. Furin, a member of the eukaryotic subtilisin family, has been shown to be an activating protease for HIV. Here, we compared the presence of furin and other mammalian subtilisins in lymphatic cells and tissues. Northern blot analyses revealed that furin and the recently discovered protease LPC/PC7 were the only subtilisin-like enzymes transcribed in such cells. Furin was identified as an enzymatically active endoprotease present in different lymphocytic, as well as monocytic, cell lines. When expressed from vaccinia virus vectors, the proprotein convertases were correctly processed, transported, and secreted into the media and enzymatically active. Coexpression of different subtilisins with the HIV envelope precursors revealed that furin and LPC/PC7 are able to cleave HIV-1 gp160. Moreover, both enzymes proteolytically processed the envelope precursor of HIV-2. gp140 was also cleaved to some extent by PC1, which is not, however, present in lymphatic cells. Furin- and LPC/PC7-catalyzed cleavage of HIV-1 gp160 resulted in biologically active envelope protein. In conclusion, among the known members of the subtilisin family, only furin and LPC/PC7 fulfill the requirements of a protease responsible for in vivo activation of HIV envelope glycoproteins.
A Design Method for Deep Well Dewatering Installations (1969)

ABSTRACT A new design method for deep well dewatering systems is given. The method analyses three dimensional flow to the multiwell systems by considering the two end points to the initial fast phase of water table fall. The method is applied to a dewatering case history and proves to be successful.
Desorption electrospray ionization (DESI) with atmospheric pressure ion mobility spectrometry for drug detection (2014)

Desorption electrospray ionization (DESI) was coupled to an ambient pressure drift tube ion mobility time-of-flight mass spectrometer (IM-TOFMS) for the direct analysis of active ingredients in pharmaceutical samples. The DESI source was also coupled with a standalone IMS demonstrating potential of portable and inexpensive drug-quality testing platforms. The DESI-IMS required no sample pretreatment as ions were generated directly from tablets and cream formulations. The analysis of a range of over-the-counter and prescription tablet formations was demonstrated for amphetamine (methylphenidate), antidepressant (venlafaxine), barbiturate (Barbituric acid), depressant (alprazolam), narcotic (3-methylmorphine) and sympatholytic (propranolol) drugs. Active ingredients from soft and liquid formulations, such as Icy Hot cream (methyl salicylate) and Nyquil cold medicine (acetaminophen, dextromethorphan, doxylamine) were also detected. Increased sensitivity for selective drug responses was demonstrated through the formation of sodiated adduct ions by introducing small quantities of NaCl into the DESI solvent. Of the drugs and pharmaceuticals tested in this study, 68% (22 total samples) provided a clear ion mobility response at characteristic mobilities either as (M + H)(+), (M - H)(-), or (M + Na)(+) ions.
Femtosecond external-cavity surface-emitting InGaAs/InP multiple-quantum-well laser (1991)

We demonstrate that a synchronously pumped In0.53Ga0.47As/InP multiple-quantum-well surface-emitting laser in an external cavity can produce 36-ps pulses with a high average power of 260 mW and a broad spectral width of 18 nm. The output pulses are strongly upchirped and could be shortened to 153 fs with peak powers exceeding 1 kW by chirp compensation with a diffraction grating pair.
The Space Environment from LEO to Deep Space (2003)

This viewgraph presentation reviews several space environments, and the hazards they pose to spacecraft operations. The presentation covers solar activity effects, galactic cosmic rays, near Earth environments including the magnetosphere, thermosphere, ionsophere, and plasmasphere, single event upsets, micrometeoroids, space debris, and an overview of conditions on other planets, especially Jupiter.
Intelligent-Well Technology: Are We Ready for Closed-Loop Control? (2006)

Abstract Over a few short years surface control of the reservoir by intelligent well technology has become a reality allowing improved efficiencies and economics by well documented measures. Downhole control valves have evolved from simple open/close zonal control to downhole chokes that allow metering of fluid rates from or to multiple producing zones. Complementary instrumentation of the wellbore provides real time data for pressure, temperature and flow. These capabilities along with computational and communication technologies provide the necessary ingredients to allow remote control of production in a variety of settings. In addition to remote control, the opportunity also exists to automate production even to the extent of closed loop control. As the complexity of surface controlled reservoir control valves has increased, so has the frequency of operators selecting microprocessor controlled surface hydraulic control systems to manipulate the valves. With microprocessor control in place at the well location, remote control options become the next logical step in the evolution of intelligent wells. Once remote operation has been chosen, the options for system architecture and communication are quite extensive. Successful implementation is a matter of effective interface engineering between the operator and the various service providers. Lessons learned in developing remote control solutions will be presented along with an outline of the remaining steps that will be needed to implement closed loop control.
Human electrophysiological and cognitive effects of exposure to ELF magnetic and ELF modulated RF and microwave fields: A review of recent studies (2002)

The investigation of weak (<500 microT), extremely low frequency (ELF, 0-300 Hz) magnetic field (MF) exposure upon human cognition and electrophysiology has yielded incomplete and contradictory evidence that MFs interact with human biology. This may be due to the small number of studies undertaken examining ELF MF effects upon the human electroencephalogram (EEG), and the associated analysis of evoked related potentials (ERPs). Relatively few studies have examined how MF exposure may affect cognitive and perceptual processing in human subjects. The introduction of this review considers some of the recent studies of ELF MF exposure upon the EEG, ERPs and cognitive and perceptual tasks. We also consider some of the confounding factors within current human MF studies and suggest some new strategies for further experimentation.
Advantageous Apodization Functions for Magnitude-Mode Fourier Transform Spectroscopy (1987)

A systematic examination of the efficacy of window functions for reducing the spectral skirt of magnitude-mode Fourier transform spectra is reported. The efficacy is examined for the general case of a damped time-domain signal, with specific cases ranging from undamped to essentially completely damped signals. The choice of the optimal window is dependent upon the required dynamic range and the amount of damping in the time-domain data. For a dynamic range of less than 100:1 and moderate damping, the Hamming window is the window of choice. For larger dynamic ranges or greater damping, the 3-term Blackman-Harris window and the Kaiser-Bessel window are the windows of choice. The 3-term Blackman-Harris window is preferred for a dynamic range of 1,000:1 and the Kaiser-Bessel window is preferred for a dynamic range of 10,000:1. The sensitivity (signal-to-noise ratio) reduction for windows is reported for a damping range from zero to essentially complete damping. All windows examined have the same sensitivity reduction within 25%.
Effect of Salt on the Equilibrium and Nonequilibrium Features of Polyelectrolyte/Surfactant Association (2011)

The impact of an electrolyte on aqueous mixtures of oppositely charged macromolecules and surfactants is usually explained by assuming an equilibrium association between the components. In this work, it is shown that the nonequilibrium character of polyelectrolyte/surfactant systems plays a crucial role in the interpretation of the effect of salt. Experimental investigations of mixtures of sodium poly(styrenesulfonate) (PSS) and hexadecyltrimethylammonium bromide (CTAB) reveal two distinct effects of added sodium chloride (NaCl). At small and moderate NaCl concentrations, the major impact of the electrolyte is manifested in the reduction of the kinetically stable composition range in which the PSS/CTAB mixtures are trapped in the nonequilibrium colloidal dispersion state. The application of high salt concentrations, however, primarily affects the equilibrium phase properties through considerably decreasing the amount of surfactant bound to the polyelectrolyte.
Fast multiscale image segmentation (2002)

We introduce a fast, multiscale algorithm for image segmentation. Our algorithm uses modern numeric techniques to find an approximate solution to normalized cut measures in time that is linear in the size of the image with only a few dozen operations per pixel. In just one pass the algorithm provides a complete hierarchical decomposition of the image into segments. The algorithm detects the segments by applying a process of recursive coarsening in which the same minimization problem is represented with fewer and fewer variables producing an irregular pyramid. During this coarsening process we may compute additional internal statistics of the emerging segments and use these statistics to facilitate the segmentation process. Once the pyramid is completed it is scanned from the top down to associate pixels close to the boundaries of segments with the appropriate segment. The algorithm is inspired by algebraic multigrid (AMG) solvers of minimization problems of heat or electric networks. We demonstrate the algorithm by applying it to real images.
UbuntuWorld 1.0 LTS - A Platform for Automated Problem Solving & Troubleshooting in the Ubuntu OS (2016)

In this paper, we present UbuntuWorld 1.0 LTS - a platform for developing automated technical support agents in the Ubuntu operating system. Specifically, we propose to use the Bash terminal as a simulator of the Ubuntu environment for a learning-based agent and demonstrate the usefulness of adopting reinforcement learning (RL) techniques for basic problem solving and troubleshooting in this environment. We provide a plug-and-play interface to the simulator as a python package where different types of agents can be plugged in and evaluated, and provide pathways for integrating data from online support forums like AskUbuntu into an automated agent's learning process. Finally, we show that the use of this data significantly improves the agent's learning efficiency. We believe that this platform can be adopted as a real-world test bed for research on automated technical support.
Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells (2012)

The results suggest that both formyl peptide receptors play an essential role in Aβ1-42-induced signal transduction in glial cells. The interaction with RAGE could explain the broad ligand spectrum of formyl peptide receptors and their important role for inflammation and the host defence against infections.
Factors involved in the high pressure liquid chromatographic separation of alkenes by means of argentation chromatography on ion exchangers: Overview of theory and new practical developments (1995)

Abstract The literature on the use and theory of silver(I) complexation (argentation) chromatography is reviewed. Apolar isomeric alkenes, for example numerous terpenes and fatty acids, can be well resolved by means of high pressure liquid chromatography on cation exchange materials coated with silver(I) ions, but unfortunately the mechanism on which these separations are based is not fully understood. As part of an attempt to provide a predictive model for the separation of volatile alkenes, the retention of more than 40 C2‐C10 olefins besides a number of C14‐pheromones and volatile terpenes is given and the results discussed. The separation is mainly governed by the type and number of double bonds (isolated, conjugated or aromatic), their steric accessibility (number and size of substituents) for complexation with silver(I) ions, the relief of inherent strain upon complexation and electron donating or withdrawing groups, or polar groups close to the double bond. Polar groups such as hydroxyls also complex weakly with silver. Other functional groups, including carbonyls, and the overall polarity of the solute play only a minor role. Similarly most solvents have only a limited influence on the selectivity and speed of separation, and function more as a transportation medium as in gas chromatography. A comparative model which gives semi‐quantitative estimations of the retention time of most volatile olefins in methanol is presented. Substituent parameters (Ag s ) which quantitatively forecast the influence of different alkyl side chains are part of this model.
Room-Temperature Hydrogen Generation from Hydrous Hydrazine for Chemical Hydrogen Storage (2009)

Rhodium nanoparticles (NPs) effectively catalyze the decomposition of hydrous hydrazine to produce hydrogen under ambient reaction conditions. Rh(0) NPs with a particle size of approximately 5 nm prepared in the presence of hexadecyltrimethyl ammonium bromide show higher catalytic activity.
The Effect of Serum Prolactin on Plasma Adrenal Androgens and the Production and Metabolic Clearance Rate of Dehydroepiandrosterone Sulfate in Normal and Hyperprolactinemic Subjects (1986)

Hyperprolactinemic patients may have increases in plasma dehydroepiandrosterone (DHA) and dehydroepiandrosterone sulfate (DHAS). We examined the effect of lowering serum PRL with bromocriptine or pituitary surgery on the serum concentrations of adrenal androgens and on the production rate (PR) and MCR of DHAS in eight hyperprolactinemic women (HP). We also examined the effect of bromocriptine therapy on adrenal androgens in five normal men. Serum DHAS was elevated in HP compared to normal women (mean +/- SEM, 254 +/- 28 vs. 182 +/- 13 microgram/dl; P less than 0.04). Serum DHA and androstenedione (delta 4) in HP were not significantly different from normal. Serum PRL fell from 160 +/- 16 to 37 +/- 9 ng/ml during or after treatment. Mean 24-h serum DHAS fell from 198 +/- 30 to 106 +/- 17 micrograms/dl (P less than 0.001) with treatment, without a change in the mean 24-h serum cortisol concentration (6.2 +/- 0.4 vs. 6.6 +/- 0.4 micrograms/dl). Thus, the DHAS to cortisol (DHAS/F) ratio fell significantly (32 +/- 5 to 17 +/- 4; P less than 0.001). This was also true of the DHAS/F ratio during ACTH stimulation (8 +/- 1 to 6 +/- 1; P less than 0.02). Similar changes were found in basal and ACTH-stimulated DHA/F ratios, whereas the basal and ACTH-stimulated delta 4/F ratios did not change significantly with treatment. Treatment lowered the PR of DHAS from 27 +/- 5 to 17 +/- 3 mg/24 h (P less than 0.03) and increased the DHAS MCR from 16 +/- 2 to 21 +/- 3 liters/24 h (P less than 0.01). Bromocriptine treatment of normal men lowered serum PRL from 15 +/- 2 to less than 2.5 ng/ml. There were no significant changes in the basal and ACTH-stimulated serum DHAS/F, DHA/F, or delta 4/F ratios or DHAS PR and MCR during bromocriptine therapy. The failure of bromocriptine to significantly alter these steroids in normal men suggests that bromocriptine was not directly responsible for the changes in HP treated with this drug. A mechanism for the increased PR of DHAS in HP was sought by examining the serum concentrations of the steroid biosynthetic intermediates relevant to DHAS production. Lowering serum PRL was associated with a decrease in basal and ACTH-stimulated 17-hydroxypregnenolone/17-hydroxyprogesterone and DHA/delta 4 ratios, suggesting an increase in 3 beta-hydroxysteroid dehydrogenase/delta 4,5-isomerase activity. However, increased gonadal secretion of the delta 4-steroids may have occurred with the fall in serum PRL.(ABSTRACT TRUNCATED AT 400 WORDS)
In-Situ Source-Template-Interface Reaction Route to Semiconductor CdS Submicrometer Hollow Spheres (2000)

Submicrometer hollow spheres of CdSare produced here (see Figure) in a one-pot in-situ source–template–interface reaction (ISTIR)—thus named because CS2 plays both the role of sulfur source and template and the main reaction region is at the CS2–water interface. Examination of the photoluminescence spectrum of these spheres indicates quantum confinement.
Evaluation of Ferrocene Derivatives as Burn Rate Modifiers in AP/HTPB-Based Composite Propellants (1999)

Some ferrocene derivatives like 2,4-dinitrophenylhydrazine derivative of acetyl ferrocene, 1-pyrrolidinylmethyl ferrocene, di-ter-butyl ferrocene and 1,3-diferrocenyl-l-butene (DFB) have been synthesised and characterised by infrared, nuclear magnetic resonance, ultraviolet, iron content, etc. To study the effect of their incorporation on performance, ammonium perchlorate/hydroxyl-terminated polybutadiene-based composite propellants containing these derivatives have been prepared and studied for burn rates, tensile strength and percentage elongation followed by their static test evaluation. A comparison of the properties of propellant containing solid and liquid ferrocene derivatives has been made with those containing Fe/sub 2/O/sub 3/ and n-butyl ferrocene, respectively. The data clearly indicates that these ferrocene derivatives are better than Fe/sub 2/O/sub 3/ and n-butyl errocene. Also, DFB is the best among these derivatives. Like composite propellants, DFB increases burn rate in fuel-rich propellants also.
High-power pulsed dye laser with Fourier-limited bandwidth (1987)

A high-peak-power, narrow-linewidth light source with a homogeneous beam profile has been constructed by modifications to a commercially available pulsed-dye-laser system. Output pulses of up to 10 mJ were generated with linewidths of about 50 MHz for 12-nsec pulses. The pulse-to-pulse frequency stability was better than the linewidth, and the center frequency could be scanned over a frequency range of 142.5 GHz at a wavelength of 600 nm. The performance of the system was demonstrated by observing the 6s2 1S0–6s7s1S0 transition in atomic mercury at 2λ = 312.8 nm and the 6s2S1/2–8s2S1/2 transition in atomic gold at 2λ = 308.9 nm using up to 1 mJ of frequency-doubled output for two-photon nonlinear absorption spectroscopy. The lifetimes of both excited states, the magnetic hyperfine splitting of the 8s2S1/2 state in gold, and the isotope shift of the 6s7s1S0 state of mercury were determined.