gebhart/patrepeval huggingface dataset:
The Data Center Manager’s Guide to Ensuring LAN Reliability and Availability (2017)

This chapter discusses some of the technologies that contribute to local area network (LAN) reliability and availability. By applying them, data center managers can ensure that their networks enhance company productivity, not detract from it. To improve the reliability of a ring network, the data center manager can add redundant links between nodes and bypass circuitry in the nodes. A LAN's reliability is a measure of its capacity to operate despite failures in communications links and equipment. Star topologies score high in LAN reliability. To improve the reliability of a ring network, the data center manager can add redundant links between nodes and bypass circuitry in the nodes. Availability is measure of a LAN's capacity to support all users who wish to access it. Availability on a bus network depends on its load, length, and access control protocol. Ring availability is lower than a mesh network's because each node on a ring must wait to receive permission before transmitting data.
Immunohistochemical Markers of Thyroid Tumors Significance and Diagnostic Applications (2003)

Immunohistochemical markers of thyroid tumors can be divided into two major categories: those related to the cell types and those related to the type of pathology. The most important markers in the first category are thyroglobulin and TTF-1 for follicular cells, and calcitonin, CEA, and chromogranin for C cells. Markers in the second category are primarily directed at papillary carcinoma and include cytokeratin 19, high-molecular weight keratin (identifiable with antibody 34betaE12), S-100 protein, HBME-1, galectin 3, and p27kip1. At the practical level, cell type-related markers are much more useful than disease-related markers. Markers said to be of prognostic value in medullary carcinomas are calcitonin, bcl-2, and N-myc.
Electrophilic Substitution of 1,1,2,2,9,9,10,10-Octafluoro[2.2]paracyclophane (1999)

Nitration of octafluoro[2.2]paracyclophane (OFP) provides an entry into the synthesis of a series of 11 monosubstituted OFPs, including the nitro, amino, chloro, bromo, iodo, hydroxy, and trifluoromethyl compounds. The NMR, mass spectrometric, and UV spectral properties of all of these derivatives are presented and discussed, and they are compared with those of its hydrocarbon analogue, [2.2]paracyclophane.
PP.06.31 (2015)

Objective: As previously reported, calibration mode significantly affects the reliability of central hemodynamic data measured by noninvasive brachial cuff-based blood pressure (BP) monitoring device, Mobil-O-Graph®. This device can also evaluate pulse wave velocity (PWV) that is regarded as a marker for arterial stiffness such as atherosclerosis, which as well needs calibration. But it is unknown which calibration mode is better for predicting coronary heart disease. The aim of this study was to compare the predicting value of PWV attained by Mobil-O-Graph® (mogPWV) between two available calibration modes in Japanese cardiovascular patients. We also compared the same way between mogPWV with brachial-ankle PWV (baPWV). Design and method: We enrolled 138 patients who underwent elective coronary angiography for suspected coronary artery disease. Significant coronary artery disease (sCAD) was defined to have at least one stenosis over 50% or history of coronary angioplasty. Prior to angiography, we measured mogPWV and calculated mogPWV1 and mogPWV2 through calibration with systolic/diastolic and mean/diastolic BP, respectively. With logistic regression analysis, we evaluated the contribution of these PWV parameters for the presence of sCAD. In selected 121 patients, we also measured baPWV and analyzed same way. Results: Two mogPWV values well correlated with each other (correlation coefficient:0.97, p < 0.001), but differed significantly (mogPWV1: 10.1 ± 2.1 m/s, mog PWV2: 11.1 ± 2.4 m/s; p < 0.01). We found markedly higher baPWV than mogPWVs (baPWV:17.9 ± 3.9 m/s). Next we evaluated the relative risk of PWV indices for sCAD. In univariate logistic regression analysis, mogPWV1 and mogPWV2 were associated with sCAD, whereas baPWV was not. In multivariate analysis, only mogPWV2 remained significant after adjusting traditional risk factors and other potential confounders (odds ratio: 1.25 [1.00–1.56]; p < 0.05). Conclusions: In utilizing a brachial Pulse Wave Analysis-Based monitoring device, PWV calibrated with mean/diastolic BP better predicts the presence of significant coronary artery disease in Japanese cardiovascular patients.
Steroid Hormone Regulation of Gene Expression (1985)

Due to the massive data sets available for drug candidates, modern drug discovery has advanced to the big data era. Central to this shift is the development of artificial intelligence approaches to implementing innovative modeling based on the dynamic, ...Read More
Ionically Gelled Alginate Foams: Physical Properties Controlled by Operational and Macromolecular Parameters (2012)

Alginates in the format of scaffolds provide important functions as materials for cell encapsulation, drug delivery, tissue engineering and wound healing among others. The method for preparation of alginate-based foams presented here is based on homogeneous, ionotropic gelation of aerated alginate solutions, followed by air drying. The method allows higher flexibility and better control of the pore structure, hydration properties and mechanical integrity compared to foams prepared by other techniques. The main variables for tailoring hydrogel properties include operational parameters such as degree of aeration and mixing times and concentration of alginate, as well as macromolecular properties such as the type of alginate (chemical composition and molecular weight distribution). Exposure of foams to γ-irradiation resulted in a dose-dependent (0-30 kGy) reduction in molecular weight of the alginate and a corresponding reduction in tensile strength of the foams.
Snowpack snow water equivalent measurement using the attenuation of cosmic gamma radiation (1998)

Incoming, background cosmic radiation constantly fluxes through the earth`s atmosphere. The high energy gamma portion of this radiation penetrates many terrestrial objects, including the winter snowpack. The attenuation of this radiation is exponentially related to the mass of the medium through which it penetrates. For the past three winters, a device measuring cosmic gamma radiation--and its attenuation through snow--has been installed at the Central Sierra Snow Laboratory, near Donner Pass, California. This gamma sensor, measuring energy levels between 5 and 15 MeV, has proved to be an accurate, reliable, non-invasive, non-mechanical instrument with which to measure the total snow water equivalent of a snowpack. This paper analyzes three winters` worth of data and discusses the physics and practical application of the sensor for the collection of snow water equivalent data from a remote location.
Thin silicon String Ribbon for high efficiency polycrystalline solar cells (2002)

Silicon ribbon of 100 /spl mu/m thickness has been grown using the String Ribbon crystal growth method. Flat, low stress material has been grown using both a tunable active afterheater and a simplified passive afterheater. The material is polycrystalline, with grain size as large as 2 cm across. Research sized cells (1 cm/sup 2/) of over 15% efficiency have been made on this material. Effects of forming gas anneal, Al back contact thickness and BSF, and PECVD SiN/MgF/sub 2/ vs. ZnS/MgF/sub 2/ were studied as a function of efficiency. The internal quantum efficiency (IQE) of the cells shows an unusually high sensitivity to light bias. Further optimization is expected to lead to 16% cells in the near future.
Discrete Intracellular Signaling Domains of Soluble Adenylyl Cyclase: Camps of cAMP? (2004)

Soluble adenylyl cyclase can function in the nucleus, defining a nuclear microdomain of adenosine 3',5'-monophosphate (cAMP) signaling. Bundey and Insel discuss the evidence for discrete signaling microdomains of cAMP, including the nucleus and caveolae, and conclude that such microdomains may be defined by the localized, subcellular expression of adenylyl cyclase isoforms.
An Enhancer of Memory and Network for Cluster and its Applications (2008)

Introduction of multi-core structures has not led to a decline in the rapid performance improvement of COTS CPU recently. On the other hand, the performance of memory and I/O systems is insufficient to catch up with that of COTS CPU. In this paper, with a view to realizing high-performance computer systems not only for HPC but also for Google-like servers, we propose concepts concerning memory systems and network systems with large extended memory. We introduce DIMMnet-3, which is a practical solution to enhance memory system and I/O system of PC, and Toshiba Cell Reference Set. Examples of the killer applications of this new type of hardware are presented. Communication mechanisms named LHS and LHC are also proposed. These are architectures for reducing latency for mixed messages with small controlling data and large acknowledge data. The latency evaluation of them is shown.
PUMPING FLUIDS RADIALLY INWARD ON CENTRIFUGAL MICROFLUIDIC PLATFORMS VIA THERMALLY-ACTUATED MECHANISMS (2011)

While manipulating fluids in microfluidic discs by centrifugal forces has several advantages, centrifugal pumping alone only permits fluids to travel uni-directionally. Rather than enlarging microfluidic discs to complete lengthy multi-step assays, a more ideal solution is to transfer fluids radially inward for further processing. To enable such fluidics, we present a novel and straightforward technique, based on thermally-actuated mechanisms, to pump fluids to more central locations on a rotating microfluidic disc.
The relative contributions of dispersion and diffusion to band spreading (resolution) in gel electrophoresis (1996)

DNA of approximately 2 kbp in length was previously found not to diffuse significantly in 1-1.5% agarose gels in the absence of an electric field, but to disperse during electrophoresis (Yarmola, E., Chrambach, A., Electrophoresis 1995, 16, 345-349). Accordingly, a process distinct from diffusion, and responsible for band spreading with migration time in gel electrophoresis, was defined as dispersion. Correspondingly, the diffusion coefficient, D(diff), was distinguished from a dispersion coefficient, D(disp). For DNA of approximately 1, 2 and 3 kbp, D(diff) and D(disp) were measured in agarose gel electrophoresis (1.0% SeaKem GTG). In that order of DNA length, D(disp)/D(diff) was found to increase from 5 to 15 to 45, showing that with increasing DNA length, time-dependent band spreading, and thus resolution in gel electrophoresis, is governed predominantly by dispersion, not diffusion. It is assumed that the essential part of electrophoretic dispersion is due to entanglement of the DNA molecule in the gel. Indirect evidence for such an entanglement derives from the observation of peak asymmetry and its interpretation by the Giddings-Weiss model.
Integer wavelet transforms based lossless audio compression. (1999)

In this paper we propose the use of integer wavelet [2] as a decorrelation stage for adaptive context based lossless audio coding. The original wideband audio signal is first decomposed in wavelet subbands. The resulted coefficients are integer valued and therefore can be transmitted using an adaptive context based method, in a lossless manner, the decoder being able to reconstruct them and afterwords to perfectly restore the audio waveform. Several ways to encode the integer wavelet coefficients are explored and the results are compared with those obtained in fullband contex adaptive coding.
Genome-wide survey of tissue-specific microRNA and transcription factor regulatory networks in 12 tissues (2014)

Tissue-specific miRNAs (TS miRNA) specifically expressed in particular tissues play an important role in tissue identity, differentiation and function. However, transcription factor (TF) and TS miRNA regulatory networks across multiple tissues have not been systematically studied. Here, we manually extracted 116 TS miRNAs and systematically investigated the regulatory network of TF-TS miRNA in 12 human tissues. We identified 2,347 TF-TS miRNA regulatory relations and revealed that most TF binding sites tend to enrich close to the transcription start site of TS miRNAs. Furthermore, we found TS miRNAs were regulated widely by non-tissue specific TFs and the tissue-specific expression level of TF have a close relationship with TF-genes regulation. Finally, we describe TSmiR (http://bioeng.swjtu.edu.cn/TSmiR), a novel and web-searchable database that houses interaction maps of TF-TS miRNA in 12 tissues. Taken together, these observations provide a new suggestion to better understand the regulatory network and mechanisms of TF-TS miRNAs underlying different tissues.
The mechanism of the electrophilic substitution of heteroaromatic compounds. Part VIII. The α-, β-, and γ-nitration of pyridine 1-oxides (1967)

Kinetic evidence confirms that the 4-nitrations of pyridine 1-oxide and several of its substituted derivatives occur on the free-base species. However, 2,6-dimethyl-4-methoxy-, 2,6-dimethoxy-, and 2,4,6-trimethoxy-pyridine 1-oxides are all shown to undergo β-nitration, which, in each case, occurs on the conjugate acid. 3,5-Dimethoxypyridine 1-oxide undergoes successive 2-mono- and 2,6-di-nitration; at least the first stage is a reaction of the conjugate acid. Reaction rates for the nitrations of the pyridine oxides are compared where possible with analogous benzenoid compounds and the results discussed in terms of partial rate factors.
Secure networked control systems against replay attacks without injecting authentication noise (2015)

This paper studies detection of replay attacks on networked control systems, assuming that the actuation and sensing signals are transmitted over an additive white Gaussian noise channel. It explores the use of the spectral estimation technique to detect the presence of a replay attack without injecting authentication noise to the control signal at the plant input. Our proposed detection method is applicable to networked feedback systems equipped with stable controllers and designed with classical and modern control system techniques. A numerical example from the literature is used to illustrate the detection results for replay attacks on networked control systems.
Synthesis and Evaluation of the Antiproliferative Effects of 1-<i>O</i>-Hexadecyl-2-<i>O</i>- methyl-3-<i>O</i>-(2‘-acetamido-2‘-deoxy-β-<scp>d</scp>-glucopyranosyl)-<i>sn</i>-glycerol and 1-<i>O</i>-Hexadecyl-2-<i>O</i>-methyl-3-<i>O</i>-(2‘-amino-2‘-deoxy-β-<scp>d</scp>-glucopyranosyl)-<i>sn</i>-glycerol on Epithelial Cancer Cell Growth (1996)

Two ether glucosyl diglyceride analogs were synthesized, and their antiproliferative activity against four epithelial cancer cell lines was evaluated. 1-O-Hexadecyl-2-O-methyl-3-O-(2'-acetamido-2'-deoxy-beta-D- glucopyranosyl)-sn-glycerol (4) was synthesized by reaction of 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranosyl chloride with 1-O-hexadecyl-2-O-methyl-sn-glycerol followed by deacetylation by methanolic hydrolysis. The N-acetyl group of 4 was removed by hydrolysis with ethanolic potassium hydroxide to form 1-O-hexadecyl-2-O-methyl-3-O-(2'-amino-2'-deoxy-beta-D-glucopyranosyl)- sn-glycerol (5). Compounds 4 and 5 inhibited the proliferation of MCF-7, A549, A427, and T84 cancer cell lines. The IC(50) values for 5 ranged from 6.5 to 12.2 microM, whereas 4 was more effective against A549 cells (IC(50) 9 microM) than against MCF-7 (IC(50) 17 microM) and A427 (IC(50) 25 microM) cells and was inactive against T84 cells. Under identical incubation conditions, compounds 4 and 5 were potent inhibitors of the proliferation of OVCAR-3 cells with IC(50) values of 12 and 4 microM, respectively, whereas ET-18-OCH(3), hexadecylphosphocholine, and erucylphosphocholine had IC(50) values of 24, >30, and >30 microM, respectively. The cell-inhibitory profile of these ether-linked glucosyl diglycerides strengthens the hypothesis that such glycolipids represent a distinct group of antitumor ether lipids, having antineoplastic activities that differ from the well-known alkylphosphocholines and alkyllysophospholipids.
Gastrointestinal allergy to soyabean protein in preruminant calves. Antibody production and digestive disturbances in calves fed heated soyabean flour. (1979)

Preruminant calves were fed heated soyabean flour as a constituent of a milk based diet. Within two weeks IgG and IgE antibodies specific for soyabean proteins appeared in their serum. To measure the rate of flow of digesta through the small intestine, other calves were cannulated in the abomasum and distal ileum. They were given single experimental feeds containing heated soyabean flour as the sole source of protein. The production of similar antibodies in these animals coincided with an increase in the rate of flow of digesta produced from an experimental feed. These results suggest the development of a gastrointestinal allergy to soyabean proteins.
Strength and Toughness of Continuous‐Alumina‐Fiber‐Reinforced Glass‐Matrix Composites (1988)

Unidirectional, continuous‐fiber composites were fabricated using polycrystalline alumina fibers and four different silicate glass matrices of differing thermal expansion. Fracture toughness measurements, strength measurements, and fractographic analysis of failed specimens are used to identify the failure mechanism. Results show that the elastic modulus mismatch between the matrix and the fibers shields the reinforcing fibers from matrix crack extension, thereby increasing composite toughness without fiber pullout. Fractographic analysis shows that fiber shielding leads to fiber failure ahead of matrix crack. Composite toughness increases linearly with increases in the residual compressive stress in the matrix phase. Ultimate composite strengths are dependent upon thermal‐expansion‐induced residual stresses and fiber strength.
Genetic relationships among avian isolates classified as Pasteurella haemolytica, ‘Actinobacillus salpingitidis’ or Pasteurella anatis with proposal of Gallibacterium anatis gen. nov., comb. nov. and description of additional genomospecies within Gallibacterium gen. nov. (2003)

Bacteria of the avian [Pasteurella haemolytica]-'Actinobacillus salpingitidis' complex have been associated with different pathological conditions in birds, among which salpingitis and peritonitis in chickens of layer type seem to dominate. The aim of this study was to classify these bacteria by comparison of 37 strains tentatively classified as biovars of the avian [P. haemolytica]-'A. salpingitidis' complex or as Pasteurella anatis. PFGE, AFLP and plasmid profiling showed that strains representing different biovars were genotypically different. Phylogenetic analysis of 22 strains characterized by 16S rRNA gene sequence comparison showed that strains classified as biovars 5, 8 and 9 were closely related to the suggested type strain of 'A. salpingitidis' (98.4-99.9% similarity), whereas the remaining strains classified in 12 biovars or as P. anatis were closely related to the type strain of P. anatis (98.1-100% similarity). The two groups were related at 95.7-97.1% similarity. The closest similarity outside this group was 94.6%, between biovar 15 and Bisgaard taxon 3. DNA-DNA hybridization was performed with 34 strains and showed binding above 85% for strains of biovars 5 and 8, including the suggested type strain of 'A. salpingitidis'. Two strains of P. anatis (F 149T and F 279) were closely related at 79% DNA binding to 27 strains of biovars 1,3, 4, 11, 12, 17-20, 22 and 24. A new genus, Gallibacterium gen. nov., is proposed to include the avian [P. haemolytica]-'A. salpingitidis'-P. anatis complex, since these taxa form a monophyletic unit with similarities above 95% on the basis of 16S rRNA sequence comparison and they are unrelated to other genera of the family Pasteurellaceae Pohl 1981. The new genus consists of Gram-negative, non-motile, rod-shaped or pleomorphic bacteria. The bacteria are catalase-, oxidase- and phosphatase-positive. Nitrate is reduced and acid is produced without gas formation from glycerol, (-)D-ribose, (+)D-xylose, (-)D-mannitol, (-)D-fructose, (+)D-galactose, (+)D-glucose, (+)D-mannose, sucrose and raffinose. The genus Gallibacterium can be separated from other genera of Pasteurellaceae by differences in catalass, symbiotic growth, haemolysis, urease, indole, acid production from (+)D-xylose, (-)D-mannitol, (-)D-sorbitol, (+)D-mannose, maltose, raffinose and dextrin and ONPG and PNPG tests. Pasteurella anatis Mutters et al. 1985 is transferred to the new genus as Gallibacterium anatis gen. nov., comb. nov. Genomospecies 1 of Gallibacterium is proposed to include the former biovars 5 and 8 of the avian [P. haemolytica]-'A. salpingitidis' complex. The type strain of Gallibacterium anatis is F 149T (=ATCC 43329T = NCTC 11413T) and the reference strain of Gallibacterium genomospecies 1 is CCM 5974.
Analog placement based on hierarchical module clustering (2008)

In analog layout design, it is very important to reduce the parasitic coupling effects and improve the circuit performance. Consequently, the most important device-level placement constraints are matching, symmetry, and proximity. However, many previous works deal with these constraints separately, and none of them mention how to handle different constraints simultaneously and hierarchically. In this paper, we first give a case study to show the needs of integrating these constraints in a hierarchical manner. Then, we present the first formulation for analog placement based on hierarchical module clustering. Our approach can handle analog placement with various constraint groups including matching, (hierarchical) symmetry, and (hierarchical) proximity groups. To our best knowledge, this is also the first work in the literature to handle floorplanning with the clustering constraint using the B*-tree based representation. Experimental results based on industrial analog designs show that our approach is very effective and efficient.
Attenuation characteristics of dominant mode in inhomogeneously filled transmission lines (1970)

For a parallel-plate or coaxial transmission line, a dielectric layer of sufficiently high permittivity placed in the space between the conductors, but adjacent to neither, can result in an attenuation coefficient which is significantly lower than that of the air-filled line. The dominant mode in these lines is shown to be a TM mode with no lower cutoff frequency. The expressions for the attenuation coefficient, derived by a perturbational technique, are applicable for any range of line dimensions and dielectric-layer permittivity and thickness.
URIC ACID IN TYPE 2 DIABETES MELLITUS (2013)

Whether Uric acid is an antioxidant or pro oxidant has been a topic of debate since long. The antioxidant activity of uric acid has been proved by various studies. This study was carried out among a group of Type 2 Diabetic patients attending Sree Balaji Medical College and Hospital. The FPG, PPPG levels were assayed along with Uric acid levels. We found a minimal decrease in serum uric acid levels among the diabetic patients in comparison with Healthy controls. The results support the idea that uric acid is an antioxidant which is being used up in combating the oxidative stress.
SELECTION OF ALTERNATIVES IN AUGMENTATION MAMMAPLASTY (1974)

COURTISS, EUGENE H. M.D.; WEBSTER, RICHARD C. M.D.; WHITE, MALVIN F. M.D. Author Information