gebhart/patrepeval huggingface dataset:
Surfactant-Free Hydrothermal Synthesis of Highly Tetragonal Barium Titanate Nanowires:  A Structural Investigation (2006)

Barium titanate nanowires synthesized with a surfactant-free hydrothermal method have been characterized by various techniques such as transmission electron microscopy (TEM), scanning electron microscopy (SEM), synchrotron X-ray diffraction, X-ray photoelectron spectroscopy (XPS), and Raman spectroscopy. The TEM and SEM analyses show the uniform cylindrical nanowires. The Rietveld refinement with synchrotron X-ray powder diffraction showed that the lattice parameters of cubic and tetragonal phases were a (= b = c) = 4.0134 Å and a (= b) = 3.9998 Å, c = 4.0303 Å, respectively. The final weighted R-factor, Rwp, was 6.75% and the goodness of fit indicator was 1.30. The mass fraction of tetragonal and cubic phases based on the refined scale factor for the two phases were 98.4% and 1.6%, respectively, which clearly show the nanowires are tetragonal. The XPS analysis has shown that as-obtained BaTiO3 nanowires were phase pure. The Raman spectra confirm the tetragonal phase of the BaTiO3 nanowires. The dielectric constant measurement shows the shift in the transition temperature (Tc = 105 °C) compared to the bulk transition temperature (Tc = 132 °C). The dielectric constant at Tc was 174 measured at 1 kHz frequency.
Kinetic Resolution of Enol Esters via Enzyme-Mediated Hydrolysis (1989)

Abstract A new type of enzyme-mediated kinetic resolution has been developed. Enol esters, such as dl-3-acetoxy-1-p-methoxy-benzyloxy-2-methoxymethoxy-3-pentene, were hydrolyzed by incubation with Bacillus coagulans to afford optically pure enol esters, and the corresponding α-substituted ketones.
Ohmic Contacts to Al0.85Ga0.15N/Al0.7Ga0.3N Heterostructure. (2018)

Abstract not provided.
An evidential fusion architecture for advanced driver assistance (2009)

In this paper, we deal with an original advanced driver assistance system (ADAS) based on the use of omnidirectional vision and an evidential fusion architecture. The panoramic perception solution permits us to address efficiently the problem of close vehicles detection but also the monitoring side traffic system. The fusion and integration of this sensorial data stream is assumed by a credibilist architecture based on the transferable belief model (TBM) of SMETS. This paradigm permits the filtering of false alarms efficiently by an optimal management of the uncertainties estimation.
Experimental Aerodynamic Control of a Long-Span Suspension Bridge Section Using Leading- and Trailing-Edge Control Surfaces (2015)

We experimentally investigate the suppression of flutter in long-span suspension bridges. A rigid sectional model of a long-span suspension bridge is mounted in a wind tunnel on a suspension system. Control surfaces, which are used to suppress flutter, are movable flaps that are fitted to the bridge section's leading and trailing edges. The flaps are responsive to the deck's heave and pitch motions. In this paper, the aerodynamic force is modeled using a thin aerofoil theory, although other modeling techniques can be used. The controller has a second-order passive transfer function with inputs of a combination of the deck's pitch angle and heave position, and outputs of the flaps' angular positions. The control system design problem is solved as an H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> optimization problem.
Off to the Organelles - Killing Cancer Cells with Targeted Gold Nanoparticles (2015)

Gold nanoparticles (AuNPs) are excellent tools for cancer cell imaging and basic research. However, they have yet to reach their full potential in the clinic. At present, we are only beginning to understand the molecular mechanisms that underlie the biological effects of AuNPs, including the structural and functional changes of cancer cells. This knowledge is critical for two aspects of nanomedicine. First, it will define the AuNP-induced events at the subcellular and molecular level, thereby possibly identifying new targets for cancer treatment. Second, it could provide new strategies to improve AuNP-dependent cancer diagnosis and treatment. Our review summarizes the impact of AuNPs on selected subcellular organelles that are relevant to cancer therapy. We focus on the nucleus, its subcompartments, and mitochondria, because they are intimately linked to cancer cell survival, growth, proliferation and death. While non-targeted AuNPs can damage tumor cells, concentrating AuNPs in particular subcellular locations will likely improve tumor cell killing. Thus, it will increase cancer cell damage by photothermal ablation, mechanical injury or localized drug delivery. This concept is promising, but AuNPs have to overcome multiple hurdles to perform these tasks. AuNP size, morphology and surface modification are critical parameters for their delivery to organelles. Recent strategies explored all of these variables, and surface functionalization has become crucial to concentrate AuNPs in subcellular compartments. Here, we highlight the use of AuNPs to damage cancer cells and their organelles. We discuss current limitations of AuNP-based cancer research and conclude with future directions for AuNP-dependent cancer treatment.
Efficient representation of the variant PSF of structured light system (2010)

This paper proposes a novel and efficient representation of the point-spread function (PSF) well suited for structured light systems used in digital profilometry. For this particular application the PSF is spatially variant over the working volume and the current parametric as well as non-parametric representations are insufficient. We validate our method using a standard data set and imagery acquired using an off-the-shelf multimedia projector and an industrial camera.
Relationship between tumour shrinkage and reduction in Ki67 expression after primary chemotherapy in human breast cancer (2001)

The association between tumour shrinkage and reduction in kinetic cell activity after primary chemotherapy in human breast cancer is still a matter of investigation. 157 patients with T2-4, N0-1, M0 breast cancer received primary chemotherapy consisting of either the CMF regimen + tamoxifen (the first consecutive 76 cases) or the single agent epirubicin (the subsequent 81). Ki67, p53, bcl2, c-erbB2 and steroid hormone receptors were evaluated immunohistochemically in tumour specimens obtained before chemotherapy and at surgery. Tumour shrinkage of >50% occurred in 72.4% of patients. Ki67 expression significantly decreased after chemotherapy; the reduction correlated with tumour response in both univariate (P < 0.005) and multivariate analysis (P = 0.02). p53, bcl-2, steroid hormone receptor and c-erbB2 immunostaining were scarcely affected. Baseline bcl2 (P = 0.04) and c-erbB2 (P = 0.02) were directly and inversely associated with the reduction in Ki67 immunostaining, respectively. Baseline p53 expression (P < 0.01) was directly related with Ki67 expression at residual tumour, whereas oestrogen receptor expression (P < 0.001) was inversely related. Ki67 at residual tumour was a better predictor for relapse-free survival (RFS) than baseline Ki67. Clinical response (P < 0.03), but not reduction in Ki67, was a significant independent predictor for disease recurrence. Chemotherapy was found to induce tumour shrinkage and to reduce the number of cells in the cell cycle, but its effect on tumour biology/aggressiveness was minimal. Reduction in Ki67 immunostaining correlated with clinical response but failed to be related to RFS. Ki67 expression at surgery rather than at baseline appears to be a better predictor for disease relapse.
Architectural Supports to Protect OS Kernels from Code-Injection Attacks (2016)

The kernel code injection is a common behavior of kernel -compromising attacks where the attackers aim to gain their goals by manipulating an OS kernel. Several security mechanisms have been proposed to mitigate such threats, but they all suffer from non-negligible performance overhead. This paper introduces a hardware reference monitor, called Kargos, which can detect the kernel code injection attacks with nearly zero performance cost. Kargos monitors the behaviors of an OS kernel from outside the CPU through the standard bus interconnect and debug interface available with most major microprocessors. By watching the execution traces and memory access events in the monitored target system, Kargos uncovers attempts to execute malicious code with the kernel privilege. According to our experiments, Kargos detected all the kernel code injection attacks that we tested, yet just increasing the computational loads on the target CPU by less than 1% on average.
Polyvinylpyrrolidone (PVP): a new precipitating agent for human and bovine factor VIII and fibrinogen (1982)

The PVP precipitating properties for human and bovine factor VIII and fibrinogen were studied and a new technique for the fractionation of factor VIII and fibrinogen was developed. The precipitation was performed at different temperatures and different PVP concentrations and the best conditions for the technique were chosen. The technique consists of two steps: (a) precipitation of factor VIII from undiluted plasma with PVP and (b) washing of the precipitate with a glycine--saline solution. The final concentrate contains 90% of the factor VIII and 20% of the fibrinogen of the original plasma.
Minimal Discrete Energy on the Sphere (1994)

We investigate the energy of arrangements of N points on the surface of a sphere in R 3 , interacting through a power law potential V = r , -2 < < 2, where r is Euclidean distance. For = 0, we take V = log(1/r). An area-regular partitioning scheme of the sphere is devised for the purpose of obtaining bounds for the extremal (equilibrium) energy for such points. For = 0, finer estimates are obtained for the dominant terms in the minimal energy by considering stereographical projections on the plane and analyzing certain logarithmic potentials. A general conjecture on the asymptotic form (as N ) of the extremal energy, along with its supporting numerical evidence, is presented. Also we introduce explicit sets of points, called "generalized spiral points", that yield good estimates for the extremal energy. At least for N 12, 000 these points provide a reasonable solution to a problem of M. Shub and S. Smale arising in complexity theory.
The Role of Quantum Confinement in p-Type Doped Indium Phosphide Nanowires (2007)

The impurity state responsible for current flow in zinc-doped indium phosphide nanowires is characterized through first-principles calculations based on a real-space implementation of density functional theory and pseudopotentials. The binding energy of the acceptor state is predicted to range from the value of the acceptor state in the bulk up to values of ∼0.2 eV in the thinner nanowires as a result of the two-dimensional quantum confinement. The location of the impurity atom within the nanomaterial is not found to play a prominent role in determining the characteristic properties of the state. Our results show that, in thin nanowires, quantum confinement can move the defect level deep into the energy gap.
Overload Performance of Several Processor Queueing Disciplines for the M/M/1 Queue (1986)

In a Variety of overloaded queueing systems (e.g., an overloaded call processing system), long delays can result either in poor service given to the customer or in customers, unknown to the system, turning "bad." For example, in switching systems, long dial tone delays can result in customers initiating dialing before receiving dial tone. In this case the system will not receive all the digits and an unsuccessful call results. This can lead to the system expending real time on unsuccessful services and, therefore, reduces the effective throughput. Thus, there is a need for control Schemes which reduce the load offered to the processor by selectively refusing service to some customers in such a way as to keep delays, for those customers which are selected for service, small. This fact has been recognized and has led to improved strategies for local switches. In this paper we analyze and compare the performance of various queueing and service disciplines for an <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">M/M/1</tex> queue. We consider LIFO and FIFO Schemes with customer rejection mechanisms corresponding to pushing out or timing out older customers in queue. Delay distributions for served customers are obtained and comparisons based upon throughput-delay tradeoffs are presented. For the situation where Customers can turn "bad" at a random time after their arrival, we compare the throughput of good customers. The results presented are a mixture of classical results, which are briefly stated, and new results which are developed in more detail. The numerical results show a dramatic effect of the queueing and Service disciplines on the overload performance and a strong dependence of the throughput of successful services on the mechanism for customers turning "bad." Although results are obtained for a single server queue, they can be used to approximately analyze overload control schemes which control access to distributed systems.
N-Alkylaminocarbazoles as potential anticonvulsant and diuretic agents (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN-Alkylaminocarbazoles as potential anticonvulsant and diuretic agentsAboo Shoeb, Falak Anwer, Randhir S. Kapil, Satya P. Popli, Prithvi Dua, and Bhola N. DhawanCite this: J. Med. Chem. 1973, 16, 4, 425–427Publication Date (Print):April 1, 1973Publication History Published online1 May 2002Published inissue 1 April 1973https://pubs.acs.org/doi/10.1021/jm00262a030https://doi.org/10.1021/jm00262a030research-articleACS PublicationsRequest reuse permissionsArticle Views95Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Interdisciplinary Bereavement Team: Defining and Directing Appropriate Bereavement Care (1996)

Hospice bereavement care often occurs in relative isolation from other program components; staff and volunteers are without the guidance, consultation and support provided through the interdisciplinary team that is enjoyed by personnel working in patient care areas. This article promotes a similar interdisciplinary team concept that has been successfully employed in one of the country's largest bereavement programs. Comprised of bereavement program staff, consultants from the patient care program, professional and lay volunteers, this interdisciplinary team defines and directs interventions provided by the bereavement care program.
Cold immersion recovery responses in the diabetic foot with neuropathy (2008)

The aim of this article was to investigate the effectiveness of testing cold immersion recovery responses in the diabetic foot with neuropathy using a contact thermography system based on thermochromic liquid crystals. A total of 81 subjects with no history of diabetic foot ulceration were assigned to neuropathy, non neuropathy and healthy groups. Each group received prior verbal and written description of the test objectives and subsequently underwent a comprehensive foot care examination. The room temperature and humidity were consistently maintained at 24 degrees C and less than 50%, respectively, with air conditioning. The right foot for each subject was located on the measurement platform after cold immersion in water at 18-20 degrees C. Whole-field thermal images of the plantar foot were recorded for 10 minutes. Patients with diabetes with neuropathy show the highest 'delta temperature', that is difference between the temperature after 10-minute recovery period and baseline temperature measured independently at all the three sites tested, that is first metatarsal head (MTH), second MTH and heel. This clinical study showed for the first time the evidence of poor recovery times for the diabetic foot with neuropathy when assessing the foot under load. A temperature deficit (because of poor recovery to baseline temperature) suggests degeneration of thermoreceptors, leading to diminished hypothalamus-mediated activity in the diabetic neuropathic group.
L'ouverture de la procréation médicalement assistée aux couples de femmes et aux femmes célibataires (2018)

Lauréate du prix du meilleur mémoire de Master 2, de la Faculté de droit de l'Université Jean Monnet de Saint-Etienne, en 2018
An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour (2016)

Serpins are important regulators of proteolytic pathways with an antiprotease activity that involves a conformational transition from a metastable to a hyperstable state. Certain mutations permit the transition to occur in the absence of a protease; when associated with an intermolecular interaction, this yields linear polymers of hyperstable serpin molecules, which accumulate at the site of synthesis. This is the basis of many pathologies termed the serpinopathies. We have previously identified a monoclonal antibody (mAb4B12) that, in single-chain form, blocks α1-antitrypsin (α1-AT) polymerisation in cells. Here, we describe the structural basis for this activity. The mAb4B12 epitope was found to encompass residues Glu32, Glu39 and His43 on helix A and Leu306 on helix I. This is not a region typically associated with the serpin mechanism of conformational change, and correspondingly the epitope was present in all tested structural forms of the protein. Antibody binding rendered β-sheet A - on the opposite face of the molecule - more liable to adopt an 'open' state, mediated by changes distal to the breach region and proximal to helix F. The allosteric propagation of induced changes through the molecule was evidenced by an increased rate of peptide incorporation and destabilisation of a preformed serpin-enzyme complex following mAb4B12 binding. These data suggest that prematurely shifting the β-sheet A equilibrium towards the 'open' state out of sequence with other changes suppresses polymer formation. This work identifies a region potentially exploitable for a rational design of ligands that is able to dynamically influence α1-AT polymerisation.
Interactions between Microbial Iron Reduction and Metal Geochemistry:  Effect of Redox Cycling on Transition Metal Speciation in Iron Bearing Sediments (2006)

Microbial iron reduction is an important biogeochemical process that can affect metal geochemistry in sediments through direct and indirect mechanisms. With respectto Fe(III) (hydr)oxides bearing sorbed divalent metals, recent reports have indicated that (1) microbial reduction of goethite/ferrihydrite mixtures preferentially removes ferrihydrite, (2) this process can incorporate previously sorbed Zn(II) into an authigenic crystalline phase that is insoluble in 0.5 M HCl, (3) this new phase is probably goethite, and (4) the presence of nonreducible minerals can inhibit this transformation. This study demonstrates that a range of sorbed transition metals can be selectively sequestered into a 0.5 M HCl insoluble phase and that the process can be stimulated through sequential steps of microbial iron reduction and air oxidation. Microbial reduction experiments with divalent Cd, Co, Mn, Ni, Pb, and Zn indicate that all metals save Mn experienced some sequestration, with the degree of metal incorporation into the 0.5 M HCl insoluble phase correlating positively with crystalline ionic radius at coordination number = 6. Redox cycling experiments with Zn adsorbed to synthetic goethite/ferrihydrite or iron-bearing natural sediments indicate that redox cycling from iron reducing to iron oxidizing conditions sequesters more Zn within authigenic minerals than microbial iron reduction alone. In addition, the process is more effective in goethite/ferrihydrite mixtures than in iron-bearing natural sediments. Microbial reduction alone resulted in a -3x increase in 0.5 M HCl insoluble Zn and increased aqueous Zn (Zn-aq) in goethite/ferrihydrite, but did not significantly affect Zn speciation in natural sediments. Redox cycling enhanced the Zn sequestration by approximately 12% in both goethite/ferrihydrite and natural sediments and reduced Zn-aq to levels equal to the uninoculated control in goethite/ferrihydrite and less than the uninoculated control in natural sediments. These data suggest that in situ redox cycling may serve as an effective method for
Optical, electrical and structural studies of nickel-cobalt oxide nanoparticles (2008)

Nanoparticles of nickel-cobalt oxide are prepared by chemical co-precipitation method. The particle size is determined from X-ray diffraction studies and TEM image. The surface morphology is revealed by SEM image. The effect of sintering on the particle size is analyzed. The FTIR studies have been used to confirm the formation of metal oxide. The characteristic stretching and bending frequencies of the sample is analyzed. The absorption spectra of the material in the UV-Vis-NIR range are recorded. An absorption band is observed to occur at 350 nm and another one around 650 nm. From the analysis of absorption spectra, the nickel-cobalt oxide (sintered at 500°C, 700°C and 900°C) are found to have direct band gaps ranging from 1.827 to 1.61 eV. Electrons are highly localized in nanoparticles and interaction between these localized states give rise to the observed band gap. The effect of temperature and frequency on the dielectric behaviour and ac electrical conductivity have been studied for nanosized samples of nickel cobalt spinel oxide prepared by chemical co-precipitation method. The dielectric permittivity of nanosized nickel cobalt spinel oxide sample is evaluated from the observed capacitance values in the frequency range 100 kHz-5 MHz and in the temperature range of 300-403 K. It is seen that with decreasing frequency, the dielectric constant increases much more obviously than that of conventional materials. As the temperature increases more and more dipoles are oriented resulting in an increase in the values of dipole moment. Space charge polarization and rotation direction polarization play a crucial role in the dielectric behaviour of this nanosized material. Further from the permittivity studies ac conductivity is evaluated.