gebhart/patrepeval huggingface dataset:
Intraoperative Indocyanine Green Fluorescence Angiography—An Objective Evaluation of Anastomotic Perfusion in Colorectal Surgery (2015)

The essentials for any bowel anastomosis are: adequate perfusion, tension free, accurate tissue apposition, and minimal local spillage. Traditionally, perfusion is measured by assessing palpable pulses in the mesentery, active bleeding at cut edges, and lack of tissue discoloration. However, subjective methods lack predictive accuracy for an anastomotic leak. We used intraoperative indocyanine green (ICG) fluorescence angiography to objectively assess colon perfusion before a bowel anastomosis. Seventy-seven laparoscopic colorectal operations, between June 2013 and June 2014, were retrospectively reviewed. The perfusion to the colon and ileum was clinically assessed, and then measured using the SPY Elite Imaging System. The absolute value provided an objective number on a 0-256 gray-scale to represent differences in ICG fluorescence intensity. The lowest absolute value was used in data analysis for each anastomosis (including small bowel) to represent the theoretical least perfused/weakest anastomotic area. The lowest absolute value recorded was 20 in a patient who underwent a laparoscopic right hemicolectomy for an adenoma, with no postoperative complications. Four low anterior resection patients had additional segments of descending colon resected. There was one mortality in a patient who underwent a laparoscopic right hemicolectomy. This study illustrates an initial experience with the SPY system in colorectal surgery. The SPY provides an objective, numerical value of bowel perfusion. However, evidence is scant as to the significance of these numbers. Large-scale randomized controlled trials are required to determine specific cutoff values correlated with surgical outcomes, specifically anastomotic leak rates.
Preferential Oxidative Addition in Palladium(0)-Catalyzed Suzuki Cross-Coupling Reactions of Dihaloarenes with Arylboronic Acids (2005)

The study of Pd(0)-/t-Bu3P system as a powerful catalyst for the cross-coupling of n,m-dihaloarenes with 1 equiv of arylboronic acids is described. Our work demonstrated that the fate of the regenerated Pd(0) catalyst can be controlled when the appropriate ligand is employed. The results described here may lead to the development of new, efficient processes to conjugate polymers with controlled length which are potentially useful in molecular electronics.
Intracardiac Electrode Detection of Early or Subendocardial Ischemia* (1982)

Subendocardial and early transmural ischemia may have significant clinical consequences while manifesting few ECG changes. Catheters were designed to be introduced transvenously into the right ventricle (RV), and coronary sinus (CS) and transarterially into the left ventricle (LV). The intracavitary electrodes were modified so that the electrodes would not contact the endocardium. In twenty-two dogs ninety-eight graded stenoses of the circumflex and left anterior descending coronary arteries were performed while electrograms (EGM) were recorded simultaneously from the intracardiac (IC) electrodes and surface ECG. Of those stenoses resulting in only nonspecific ECG changes, there were specific ischemic changes on 100% of LV, 60% of RV, and 89% of CS electrograms. Of those stenoses which resulted in no ECG change, there were specific ischemic changes in the 9/31 (29%) of LV, 3/31 (10%) of RV, and 6/31 (19%) of CS electrograms. Recognizable patterns of change occur on the intracardiac electrograms in response to both stenosis and reperfusion, earlier than any change on the ECG. Besides being more sensitive, intracardiac electrodes allowed for the detection of ischemia even in the presence of intraventricular conduction defects, strain patterns, and possibly other situations which might otherwise mask ischemic changes on the ECG.
Syntaxin 17 (2013)

The phagophore (also called isolation membrane) elongates and encloses a portion of cytoplasm, resulting in formation of the autophagosome. After completion of autophagosome formation, the outer autophagosomal membrane becomes ready to fuse with the lysosome for degradation of enclosed cytoplasmic materials. However, the molecular mechanism for how the fusion of completed autophagosomes with the lysosome is regulated has not been fully understood. We discovered syntaxin 17 (STX17) as an autophagosomal soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE). STX17 has a hairpin-type structure mediated by two transmembrane domains, each containing glycine zipper motifs. This unique transmembrane structure contributes to its specific localization to completed autophagosomes but not to phagophores. STX17 interacts with SNAP29 and the lysosomal SNARE VAMP8, and all of these proteins are required for autophagosome-lysosome fusion. The late recruitment of STX17 to completed autophagosomes could prevent premature fusion of the lysosome with unclosed phagophores.
Antoine Leroux, New Mexico Guide (1941)

A NTOINE LEROUX was born of French Canadian parents who ca~e to St. Louis at an early day.The dates which Leroux himself gave at differe"nt times show some discrepancy, but he seems to have been born in, or about, the year 1803. 1 At the age of nineteen, he was one of the young men who answered an advertisement of Sir William Henry Ashley; and he got his first acquaintance of the Far West as a member of the Ashley expedition of 1822.About two years later, perhaps by the summer of 1824, he arrived in Taos, New Mexico, and his written statement of March, 1853, shows that he regarded Taos as his home from the time of his marriage.This took place in November, 1833, as appears from the marriage register now in the Archiepiscopal Archive of Santa Fe. 2 It would seem that Leroux soon came to be regarded as 1.Since Ashley did not enter the fur trade until 1822, Leroux could not have been employed by him in 1820 as he wrote in the statement for Senator Benton in 1858.See below.2. This marriage record is of such interest in several ways that its text is given in full at the close of Mr. Foreman's paper.A tradition at Taos has it that Leroux, in later life, moved across the mountains into the Mora valley and died there.This was true of Antonio Ledoux (one of the witnesses at the marriage of Leroux).The land holding in "los valles de Santa Gertrudis de 10 de Mora," attributed by Twitchell (Spanish Archives.
Biological Control of Northern Jointvetch (<i>Aeschynomene virginica</i>) in Rice (<i>Oryza sativa</i>) and Soybeans (<i>Glycine max</i>) — a Researcher's View (1986)

Weed control strategies for rice ( Oryza sativa L.) and soybean [ Glycine max (L.) Merr.] emphasize integration of cultural and chemical practices (16, 30, 31). Numerous herbicides are registered and used as preplant, preemergence, or post-emergence applications for control of weeds in rice and soybean (3, 16, 25). Although these herbicide treatments control most of the problem weeds in rice and soybean, most fail to control northern jointvetch [ Aeschynomene virginica (L.) B.S.P. # AESVI] in either crop. The two most effective herbicides, 2,4,5-T [2-(2,4,5-trichlorophenoxy) acetic acid] and silvex [2-(2,4,5-trichlorophenoxy) propanoic acid], for control of northern jointvetch in rice have been under the U.S. Environmental Protection Agency's (EPA) Rebuttal Presumption Against Registration (RPAR) process which may ultimately cancel the use of both herbicides in rice (50). New, effective control strategies are needed for control of northern jointvetch in rice and soybean.
Self-Calibration of Accelerometer Arrays (2016)

A gyroscope-free inertial measurement unit employs solely accelerometers to capture the motion of a body in the form of its linear and angular acceleration as well as its angular velocity. For that, multiple transducers are fixed at distinct locations of the body that together form an accelerometer array. To accurately estimate the motion, the poses of the sensors, i.e., their positions and orientations, must be known precisely. Unfortunately, these parameters are typically hard to assess. Current state-of-the-art calibration methods are able to reconstruct the geometrical sensor configuration based on a set of motion data and corresponding acceleration measurements. However, to impose a reference motion on the sensor array and to capture that motion with the necessary accuracy requires sophisticated laboratory equipment. In this paper, we present a method to estimate the transducer poses using only their own measurements without depending on reference motion data. It is based on an iterative graph optimization that considers both the sensor poses and the motion as target variables. Initially, this results in infinitely many solutions. We reduce the solutions to only one global optimum by explicitly modeling the used triple-axis accelerometers as sensor triads and furthermore taking the temporal dependence of the acceleration samples into account. We compare our method to the conventional calibration using reference data in terms of its estimation accuracy. Furthermore, we analyze the convergence properties of our method by evaluating its tolerance to initial pose deviations. For both, we use synthetic and experimental data recorded on a 3-D rotation table.
Performance factors for progressing cavity pumps (2005)

Progressing cavity pumps have a strong representation in a wide range of industries, their popularity being attributable to the ability to handle viscous liquids and fluids with high solids content. Bryan Orchard looks at factors influencing performance and recent developments.
Effects of a whey protein product and spray-dried animal plasma on growth performance of weanling pigs. (2000)

Five experiments were conducted to evaluate the effects of a high-protein, whey protein product (WPP; 73% CP, 6.8% lysine, 12.8% fat, and 5% lactose) and spray-dried animal plasma (SDAP) on growth performance of weanling pigs. In all experiments, pigs were fed experimental diets from d 0 to 14 after weaning in a pelleted form and then a common diet in meal form for the remainder of the experiment. Dietary treatments were established by substituting WPP or SDAP for dried skim milk (Exp. 1) or soybean meal (Exp. 2, 3, 4, and 5) in the control diet. In Exp. 1, we maintained a constant level of lactose in all diets by adjusting the amount of added crystalline lactose. The amount of lactose in diets used in Exp. 2 through 5 varied slightly by the addition of WPP. In Exp. 1 and 2, 180 weanling pigs (initially 5.8 kg and 19 +/- 1 d of age or 5.5 kg and 17 +/- 1 d of age, respectively) were used. Treatment diets contained SDAP (2.5 and 5%) or WPP (2.7 and 5.4% in Exp.1, and 2.5 or 5.0% in Exp. 2). In Exp. 1, from d 0 to 7 after weaning, ADG and ADFI increased with increasing SDAP (linear, P < .01). No other treatment effects were observed during the d 0 to 14 period. In Exp. 2, from d 0 to 14 after weaning, ADG and G:F increased (linear, P < .04) with increasing SDAP or WWP. In Exp. 3, 305 weanling pigs (initially 4.1 kg and 12 +/- 1 d of age) were used. The control diet contained 2.5% SDAP. The experimental diets were similar to the control diet but contained an additional 2.5 or 5.0% SDAP or 2.5 or 5.0% WPP. From d 0 to 14 after weaning, ADG, ADFI, and G:F increased (quadratic, P < .05) with increasing SDAP up to 5.0%. Increasing WPP increased ADG (quadratic, P < .07) and ADFI (linear, P < .09). In Exp. 4 and 5, 329 and 756 weanling pigs (initially 4.1 kg and 12 +/- 1 d of age and 5.2 kg and 18 +/- 1 d of age, respectively) were fed diets in which WPP was substituted for 0, 25, 50, 75, and 100% (Exp. 4) or 0, 50, and 100% (Exp. 5) of the SDAP in the control diet. In Exp. 4 and 5, from d 0 to 14 after weaning, pigs fed a 1:1 blend of each protein source had better ADG (quadratic, P < .04) than those only fed SDAP. In conclusion, WPP can be used in combination with or as a total replacement for SDAP in diets for weanling pigs without reducing performance.
Minipump for Two-Phase Cooling Loop (2000)

<span class="label">1</span> <div class="htmlview paragraph">This paper describes the conception and development status of a mini pump for two phases cooling loops. This pump is able to transport heat until 500 watts with a very low mass, low power consumption, and for a long lifetime (up to15 years)</div>
Highly Threo Diastereoselective Anionic Polymerization of <i>(E</i><i>,</i><i>E</i><i>)</i>-Methyl Sorbate Catalyzed by a Bulky Organoaluminum Lewis Acid (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTHighly Threo Diastereoselective Anionic Polymerization of (E,E)-Methyl Sorbate Catalyzed by a Bulky Organoaluminum Lewis AcidAkinori Takasu, Masaya Ishii, Yoshihito Inai, and Tadamichi HirabayashiView Author Information Department of Environmental Technology and Urban Planning, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan Cite this: Macromolecules 2001, 34, 19, 6548–6550Publication Date (Web):August 14, 2001Publication History Received7 May 2001Revised3 July 2001Published online14 August 2001Published inissue 1 September 2001https://pubs.acs.org/doi/10.1021/ma010790chttps://doi.org/10.1021/ma010790crapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views346Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anionic polymerization,Hydrogenation,Polymerization,Polymers,Stereoselectivity Get e-Alerts
Stabilizing Control in Emergencies Part: 2. Control by Local Feedback (1981)

New methods are introduced for the stabilization of the power system during violent swings after major disturbances. These techniques utilize existing or attainable measurements, computer facilities, and devices such as short rating resistors, capacitors, or fast valving. Stabilizing action is based on a new Observation Decoupled State Space which is introduced in a companion paper [1]. Components of this state space associated with individual buses can be computed locally from local conventional measurements. The origin is always the stable system equilibrium-the target of the control. In this paper methods are introduced to track this target by purely local feedback. No telemetering is involved in either the state estimation or the control. Stability of the control in a global domain was proven. Excellent performance is demonstrated by simulation on a 118 bus system with a consistent, up to ten-fold, increase in the critical clearing times.
Efficient incorporation of diverse components into metal organic frameworks via metal phenolic networks (2017)

Metal phenolic networks (MPNs) were used for the first time for the construction of core@shell MOF materials. Diverse functional nanocores with different shapes and sizes could be coated with ZIF-8 shells mediated by MPNs. The obtained Fe<sub>3</sub>O<sub>4</sub>@TA-Fe<sup>3+</sup>@ZIF-8 powder showed a superhydrophobic nature which could efficiently absorb n-hexane from water.
Treatment of spontaneous leukemia in AKR mice with chemotherapy, immunotherapy, or interferon. (1976)

AKR mice are genetically destined to develop Gross (RNA) virus-induced lymphatic leukemia. Leukemic AKR mice treated with combination vincristine, cyclophosphamide (Cytoxan), and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea sustained a 180% increase of life-span. Combination chemotherapy plus immunization with neuraminidase-treated allogeneic (Gross virus-induced) G2G leukemic cells intradermally resulted in 35% of animals surviving beyond 150 days without evidence of the disease. It is significant that allogeneic E2G leukemic cells as immunogen were as effective in prolonging the life-span of the immunized leukemic AKR mice as were syngeneic leukemic thymocytes. Virazole (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide), an antiviral compound, alone showed no apparent antitumor effect. However, in experiments in which the clinically diagnosed leukemic AKR mice received a combination of cytoreductive therapy [vincristine plus prednisone or, more effectively, vincristine, Cytoxan plus 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, followed by Virazole], there was a noticeable reduction of the viral titer, a delay in the reappearance of viable clonogenic cells, and an increase in the survival time for the leukemic AKR mice as compared to those receiving cytoreductive therapy alone. The effectiveness of purified mouse interferon in AKR mice was also examined. The decrease in the viral titer of animals that received interferon treatment was markedly greater than of those receiving a combination of cytoreductive therapy with Virazole or immunotherapy. The administration of mouse interferon had a direct effect on the appearance of the spontaneous leukemia in AKR mice. The median life-span of the control animals was 36 weeks, whereas 45% of the AKR mice treated with five doses of 5 X 10(4) units of interferon are still alive at 54 weeks of age. Thus, interferon not only reduces the Gross murine leukemia virus titer in the chronically infected AKR mice but also significantly delays the appearance of the primary lymphoma.
Hot roating plasma in the PSP-2 experiment (1991)

Studies have been carried out of an MHD stable rotating plasma with the following parameters: mean ion energy up to 40 keV in the laboratory frame of reference or up to 20 keV in the rotating frame of reference, plasma density 3 × 1011 cm−3 (and up to 1012 cm−3 in special regimes), mean energy of electrons 0.1−1.0 keV (non-Maxwellian spectrum), lifetime of ions 10−4 s (determined by charge exchange), and plasma volume 0.1 m3, in experiments on the PSP-2 device. The field strength in the plasma was about 20 kV/cm, and the total voltage achieved 0.5 MV. The MHD stabilization conditions are in agreement with the theoretical estimates. A hot plasma was created in a high voltage × discharge, the cold hydrogen gas having been puffed without any heating or plasma injection systems.
Interplay of form and material birefringence in photonic crystal fibers: application for sensing (2004)

We discuss how material anisotropy influences the modal birefringence of photonic crystal fibers. We introduce an efficient numerical method for the calculation of the modal structure which accounts for material anisotropy. The approach relies on solving the fully vectorial wave equation for the transverse magnetic field and the respective propagation constants within the general framework of plane-wave methods. This analysis is relevant to certain application areas, and, in particular, to fiber sensing, where material birefringence arises due to pressure or mechanical strain. We compare the sensitivity calculations with experimental data and discuss novel potentialities of photonic crystal fibers for sensing; the discussion includes the possibility of temperature insensitivity, a wide range of sensitivity tailoring options, and novel sensing mechanisms with the use of the photonic bandgap.
Blood Activity of Cu/Zn Superoxide Dismutase, Glutathione Peroxidase and Catalase in Alzheimer’s Disease: A Case-Control Study (1990)

Cu/Zn superoxide dismutase (Cu/Zn SOD), glutathione peroxidase (GPx) and catalase, which are the three main enzymes involved in cellular protection against damage due to oxygen-derived free radicals have been assayed in plasma and erythrocytes obtained from subjects with dementia of the Alzheimer type (DAT) and from controls. Blood samples were obtained from 25 patients with DAT and from age-matched subjects without diagnoses of neurological disease (non-DAT), as well as from younger individuals (reference group). Using appropriate statistical procedures, the three enzyme activities measured in blood of the elderly were decreased if compared to the younger reference group. Moreover, a significant increase in erythrocyte Cu/Zn SOD and catalase activities of DAT patients was observed compared to the non-DAT group. These results are discussed taking the free radical theory of aging into consideration.
Microporous Manganese Formate:  A Simple Metal−Organic Porous Material with High Framework Stability and Highly Selective Gas Sorption Properties (2003)

Novel microporous metal-organic framework material composed of Mn(II) and formate ions displays permanent porosity, high thermal stability, and size-selective gas sorption behavior. The framework is stable enough to maintain single crystallinity after the complete guest removal at 150 degrees C under a reduced pressure. Most importantly, it selectively adsorbs H2 and CO2 but not N2 and other gases with larger kinetic diameters, which appears to be due to the small aperture of the channels. Despite a moderate H2 storage capacity, which is however still higher than that of any zeolite, its H2 surface coverage is one of the highest among the known microporous materials. Thus this new zeolite-like material made of a simple organic building block may find useful applications in gas separation and sensor.
Controlled-source analogous circuits and SPICE models for piezoelectric transducers (1994)

Transmission line analogous circuits for piezoelectric transducers are developed which employ controlled sources rather than the traditional transformer to model the coupling between the electrical and the mechanical systems. A novel method is used to derive each model that consists of adding a term that is equal to zero to one of the device electromechanical equations. When this is done, it is shown that the equations can be cast into the form of the familiar telegraphist's equations for the voltage and current on an electrical transmission line. The circuits are derived for both the thickness-mode piezoelectric transducer and the side-electrode bar piezoelectric transducer. SPICE models of the analogous circuits are presented and an example simulation is given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Oncolytic Viruses for Cancer Therapy: Barriers and Recent Advances (2019)

Oncolytic viruses (OVs) are powerful new therapeutic agents in cancer therapy. With the first OV (talimogene laherparepvec [T-vec]) obtaining US Food and Drug Administration approval, interest in OVs has been boosted greatly. Nevertheless, despite extensive research, oncolytic virotherapy has shown limited efficacy against solid tumors. Recent advances in viral retargeting, genetic editing, viral delivery platforms, tracking strategies, OV-based gene therapy, and combination strategies have the potential to broaden the applications of oncolytic virotherapy in oncology. In this review, we present several insights into the limitations and challenges of oncolytic virotherapy, describe the strategies mentioned above, provide a summary of recent preclinical and clinical trials in the field of oncolytic virotherapy, and highlight the need to optimize current strategies to improve clinical outcomes.