gebhart/patrepeval huggingface dataset:
Composition influence on the physical and electrical properties of SrxTi1−xOy-based metal-insulator-metal capacitors prepared by atomic layer deposition using TiN bottom electrodes (2009)

In this work, the physical and electrical properties of SrxTi1−xOy (STO)-based metal-insulator-metal capacitors (MIMcaps) with various compositions are studied in detail. While most recent studies on STO were done on noblelike metal electrodes (Ru, Pt), this work focuses on a low temperature (250 °C) atomic layer deposition (ALD) process, using an alternative precursor set and carefully optimized processing conditions, enabling the use of low-cost, manufacturable-friendly TiN electrodes. Physical analyses show that the film crystallization temperature, its texture and morphology strongly depends on the Sr/Ti ratio. Such physical variations have a direct impact on the electric properties of SrxTi1−xOy based capacitors. It is found that Sr-enrichment result in a monotonous decrease in the dielectric constant and leakage current as predicted by ab initio calculations. The intercept of the EOT vs physical thickness plot further indicates that increasing the Sr-content at the film interface with the bottom TiN would result in lower interfacial equivalent-oxide thickness.
Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation (2015)

New independent findings from different β-cell regeneration models, contributed by different research groups, have provided compelling evidence to highlight a previously unappreciated role for macrophages in β-cell proliferation. Additional dissection of the underlying mechanisms and cell-cell crosstalk might shed new light on strategies to increase the functional β-cell mass in vivo and on β-cell replacement therapies.
Push technology: driving traditional online into a corner (1997)

Place de cette technologie dans le marche de l'information. Liste de 19 societes presentant une offre dans ce domaine
Isoform-specific Subcellular Localization among 14-3-3 Proteins in<i>Arabidopsis</i>Seems to be Driven by Client Interactions (2005)

In most higher eukaryotes, the predominantly phosphoprotein-binding 14-3-3 proteins are the products of a multigene family, with many organisms having 10 or more family members. However, current models for 14-3-3/phosphopeptide interactions suggest that there is little specificity among 14-3-3s for diverse phosphopeptide clients. Therefore, the existence of sequence diversity among 14-3-3s within a single organism begs questions regarding the in vivo specificities of the interactions between the various 14-3-3s and their clients. Chief among those questions is, Do the different 14-3-3 isoforms interact with different clients within the same cell? Although the members of the Arabidopsis 14-3-3 family of proteins typically contain highly conserved regions of sequence, they also display distinctive variability with deep evolutionary roots. In the current study, a survey of several Arabidopsis 14-3-3/GFP fusions revealed that 14-3-3s demonstrate distinct and differential patterns of subcellular distribution, by using trichomes and stomate guard cells as in vivo experimental cellular contexts. The effects of client interaction on 14-3-3 localization were further analyzed by disrupting the partnering with peptide and chemical agents. Results indicate that 14-3-3 localization is both isoform specific and highly dependent upon interaction with cellular clients.
Complete Genome Sequence of Acidovorax sp. Strain KKS102, a Polychlorinated-Biphenyl Degrader (2012)

We report the complete genome sequence of Acidovorax sp. strain KKS102, a polychlorinated-biphenyl-degrading strain isolated from a soil sample in Tokyo. The genome contains a single circular 5,196,935-bp chromosome and no plasmids.
Computing optical flow in resistive networks and in the primate visual system (2003)

It is shown how the well-known algorithm of B. Horn and B.C. Schunk (1981) for computing optical flow, based on minimizing a quadratic functional using a relaxation scheme, maps onto two different kinds of massive parallel hardware: either resistive networks which are attractive for their technological potential, or neuronal networks related to the ones occurring in the motion pathway in the primate's visual system. If the x and y components of the motion field are coded explicitly as voltages within electrical circuits, simple resistive networks solve for the optical flow in the presence of motion discontinuities. These networks are being implemented into analog, subthreshold CMOS VLSI (complementary metal oxide semiconductor very large-scale integration) circuits. If velocity is represented within a population of direction selective cells, the resulting neuronal network maps onto the primate's striate and extrastriate visual cortex (middle temporal area). The performance of the network mimicks a large number of psychological illusions as well as electrophysical findings.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Compact, Microprocessor-Based ECG ST-Segment Analyzer for the Operating Room (1982)

We describe a microprocessor-based device for analyzing ST-segment changes of the electrocardiogram in the operating room during general anesthesia. The device identifies significant components of the ECG waveform, detects arrhythmias, and performs ST-segment measurements. Measured values of heart rate, QRS duration, R-wave magnitude, and ST-segment level, slope, area, and index are selectively displayed on a front-panel numeric display and can be recorded in analog form with an FM tape recorder. Provided are details of the battery-operated hardware, the ST-analysis software, and the results of 60 h of clinical trials. Possible uses are proposed for trend analysis during anesthesia.
Silica-Coated Quantum Dots for Optical Evaluation of Perfluorocarbon Droplet Interactions with Cells (2011)

There has been recent interest in developing new, targeted, perfluorocarbon (PFC) droplet-based contrast agents for medical imaging (e.g., magnetic resonance imaging, X-ray/computed tomography, and ultrasound imaging). However, due to the large number of potential PFCs and droplet stabilization strategies available, it is challenging to determine in advance the PFC droplet formulation that will result in the optimal in vivo behavior and imaging performance required for clinical success. We propose that the integration of fluorescent quantum dots (QDs) into new PFC droplet agents can help to rapidly screen new PFC-based candidate agents for biological compatibility early in their development. QD labels can allow the interaction of PFC droplets with single cells to be assessed at high sensitivity and resolution using optical methods in vitro, complementing the deeper depth penetration but lower resolution provided by PFC droplet imaging using in vivo medical imaging systems. In this work, we introduce a simple and robust method to miscibilize silica-coated nanoparticles into hydrophobic and lipophobic PFCs through fluorination of the silica surface via a hydrolysis-condensation reaction with 1H,1H,2H,2H-perfluorodecyltriethoxysilane. Using CdSe/ZnS core/shell QDs, we show that nanoscale, QD-labeled PFC droplets can be easily formed, with similar sizes and surface charges as unlabeled PFC droplets. The QD label can be used to determine the PFC droplet uptake into cells in vitro by fluorescence microscopy and flow cytometry, and can be used to validate the fate of PFC droplets in vivo in small animals via fluorescence microscopy of histological tissue sections. This is demonstrated in macrophage and cancer cells, and in rabbits, respectively. This work reveals the potential of using QD labels for rapid, preclinical, optical assessment of different PFC droplet formulations for their future use in patients.
Integrated Hole and Countersink Inspection of Aircraft Components (2013)

<div class="section abstract"><div class="htmlview paragraph">Precision hole inspection is often required for automated aircraft assembly. Direct contact measurement has been proven reliable and accurate for over 20 years in production applications. At the core of the hole measurement process tool are high precision optical encoders for measurement of diameter and countersink depth. Mechanical contact within the hole is via standard 2-point split ball tips, and diametric data is collected rapidly and continuously enabling the system to profile the inner surface at 0 and 90 degrees. Hole profile, countersink depth, and grip length data are collected in 6 seconds. Parallel to the active process, auto-calibration is performed to minimize environmental factors such as thermal expansion. Tip assemblies are selected and changed automatically. Optional features include concave countersink and panel position measurement.</div></div>
Personalized Driver Stress Detection with Multi-task Neural Networks using Physiological Signals (2017)

Stress can be seen as a physiological response to everyday emotional, mental and physical challenges. A long-term exposure to stressful situations can have negative health consequences, such as increased risk of cardiovascular diseases and immune system disorder. Therefore, a timely stress detection can lead to systems for better management and prevention in future circumstances. In this paper, we suggest a multi-task learning based neural network approach (with hard parameter sharing of mutual representation and task-specific layers) for personalized stress recognition using skin conductance and heart rate from wearable devices. The proposed method is tested on multi-modal physiological responses collected during real-world and simulator driving tasks.
Stress Analysis and Design Optimization for Low-<inline-formula> <tex-math notation="LaTeX">$k$ </tex-math></inline-formula> Chip With Cu Pillar Interconnection (2015)

Cu pillar technology can cater for high I/O, fine pitch, and miniaturization requirements compared with wire bonding and conventional solder flip-chip technologies. However, chip-package interaction of Cu pillar and low-k chip is a critical challenge during assembly process due to stiffer Cu pillar structure compared with conventional solder bump. Thermo-compression bonding (TCB) process was adopted and used for fine pitch Cu pillar assembly on Cu/low-k chip to reduce the package warpage and low-k stress. In this paper, a novel TCB process modeling methodology using a 2-D axisymmetric finite-element model with global-local technique was demonstrated by considering step-by-step process conditions. The TCB modeling method was validated by the experimental data. The simulation results show that TCB process results in much lower package warpage and low-k stress compared with conventional reflow (RF) process. Based on the proposed TCB modeling method, the comprehensive parametric studies were conducted to optimize TCB process and Cu pillar design for package reliability improvement, including bonding process conditions, Cu pillar structure design, package geometry, and packaging material selection. RF process-induced package warpage and low-k stress were also simulated for comparison. The final package and assembly solution was successfully achieved based on the suggestions and recommendations provided by the simulation results.
Longitudinal contribution of maternal and paternal depression to toddler behaviors: Interparental conflict and later depression as mediators. (2015)

Maternal postpartum depression has been linked to later internalizing and externalizing behaviors in offspring; whereas, the consequences of paternal postpartum depression have received little attention. Further, research has produced inconsistent findings regarding mechanisms accounting for the link between postpartum depression and subsequent child behaviors. The purpose of this longitudinal study was to extend previous research by examining simultaneously the unique effects of maternal and paternal postpartum depression on child behaviors, and exploring the potential mediating roles of later depression and interparental conflict. The study included a sample of 199 couples whose index child was an average age of 4.5 months at the postpartum assessment and 45.5 months at the toddlerhood assessment. Findings suggest that both maternal and paternal depression in the postpartum period set the stage for future parental depression and interparental conflict. Parental depression during toddlerhood was associated with child internalizing and externalizing behaviors and represents a primary mechanism through which postpartum depression is linked to child behaviors for both male and female children. Interparental conflict was not a significant mediator, but may have an indirect role in internalizing and externalizing behaviors through its associations with parental depression. Clinical implications include the need for pediatric primary care providers to routinely implement systematic screening practices for parental mental health and to provide referrals to couples and parenting programs when depression is detected.
Candidal Endophthalmitis After Keratoplasty (2001)

Case reports confirm the occurrence of donor-to-host transmission of postkeratoplasty candidal endophthalmitis. Despite the low reported incidence, the poor prognosis of the affected eye in the ajority of these cases suggests the need for antifungal supplementation of cold preservation media and other preventative strategies.
A completely automatic french curve: fitting spline functions by cross validation (1975)

The cross validation mean square error technique is used to determine the correct degree of smoothing, in fitting smoothing solines to discrete, noisy observations from some unknown smooth function. Monte Cario results snow amazing success in estimating the true smooth function as well as its derivative.
Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae (1993)

The Saccharomyces cerevisiae HIS7 gene was cloned by its location immediately downstream of the previously isolated and characterized ARO4 gene. The two genes have the same orientation with a distance of only 416 bp between the two open reading frames. The yeast HIS7 gene represents the first isolated eukaryotic gene encoding the enzymatic activities which catalyze the fifth and sixth step in histidine biosynthesis. The open reading frame of the HIS7 gene has a length of 1,656 bp resulting in a gene product of 552 amino acids with a calculated molecular weight of 61,082. Two findings implicate a bifunctional nature of the HIS7 gene product. First, the N-terminal and C-terminal segments of the deduced HIS7 amino acid sequence show significant homology to prokaryotic monofunctional glutamine amidotransferases and cyclases, respectively, involved in histidine biosynthesis. Second, the yeast HIS7 gene is able to suppress His auxotrophy of corresponding Escherichia coli hisH and hisF mutants. HIS7 gene expression is regulated by the general control system of amino acid biosynthesis. GCN4-dependent and GCN4-independent (basal) transcription use different initiator elements in the HIS7 promoter.
Unsymmetrical α‐diimine nickel (II) complex with rigid bicyclic ring ligand: Synthesis, characterization, and ethylene polymerization in the presence of AlEt<sub>2</sub>Cl (2007)

Abstract Unsymmetrical α‐diimine ligand 1 was successfully synthesized via condensation of trimethylaluminum (TMA) metalated 2‐methyl‐6‐isopropyl‐aniline with rigid bicyclic aliphatic diketone camphorquinone. Syn‐ and anti‐stereoisomers were detected by 13 C NMR in the condensation product. The corresponding α‐diimine nickel (II) complex 1 was prepared from the exchange reaction of (DME)NiBr 2 with the ligand 1 , and displayed high activity for ethylene polymerization in the presence of diethylaluminum chloride (AlEt 2 Cl). The resultant polymers were confirmed by gel permeation chromatography and 13 C NMR characterization to be broad molecular weight distribution polyethylene with various branches, and high degree of branching, even at low polymerization temperature −10°C. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
PERSPECTIVAS DE VIDA NO CAMPO DE CONCENTRAÇÃO AUSCHWITZ (2016)

O artigo tem por objetivo analisar a narrativa de testemunho Primo Levi em “É isto um homem?” em ênfase sobre a perspectiva de vida no campo, os privilégios que alguns prisioneiros conseguiam, os regulamentos e as estratégias de sobrevivência. Analisaremos também a relação entre memória do testemunho Primo Levi e história, para isto utilizaremos considerações de Jeanne Marie Gagnebin, Giorgio Agamben, Hannah Arendt, Joselaine Brondani Medeiros e Primo Levi. Dentre os resultados a narrativa de testemunho, e inclusive “É isto um homem? ” e a historiografia são importantes para a conservação do passado e manter viva a memória daqueles que estiveram nos campos de concentração. Sendo dignos de memórias aqueles que não sobreviveram e morreram sem identificação nos campos e também aqueles que sobreviveram e testemunharam o ocorrido.
SREBP-1 Mediates Activation of the Low Density Lipoprotein Receptor Promoter by Insulin and Insulin-like Growth Factor-I (1996)

Transcription of the low density lipoprotein (LDL) receptor gene is regulated by intracellular cholesterol concentration, hormones, and growth factors. We studied the mechanisms by which insulin and estradiol stimulate promoter activity of the LDL receptor gene. Hormonal effects were analyzed in HepG2 cells after transient transfection with promotor reporter gene constructs. Successive 5' deletions of the LDL receptor promoter fragment from -537 to +88 revealed the sterol regulatory element 1 (SRE-1) between -65 and -56 as an insulin- and estradiol-sensitive cis-element. If the SRE-1 is point mutated at position -59 (C to G), which abolishes the binding of the SRE binding proteins (SREBP-1 and SREBP-2), no insulin or estradiol stimulatory effect on reporter gene expression was observed, indicating a role of SRE binding proteins in this regulatory mechanism. The concentration of the 125-kDa membrane-integrated SREBP-1 precursor protein in LDL repressed HepG2 cells is not altered by hormone treatment. Concentrations of SREBP-1 mRNA and precursor protein are reduced significantly by high and stable expression of an SREBP-1 antisense cDNA fragment in HepG2 cells (SREBP1(-) cells). Transfection of SREBP1(-) cells with promoter construct phLDL4 (-105 to +88) reduces induction of reporter gene activity by insulin and insulin-like growth factor-I to 35 and 17%, respectively, compared with HepG2 cells. The stimulatory effect of estradiol remains unchanged, and the inductions by pravastatin are enlarged. We conclude that different regulatory effects converge at SRE-1, but that SREBP-1 is selectively involved in the signal transduction pathway of insulin and insulin-like growth factor-I leading to LDL receptor gene activation.
Fast electronic resistance switching involving hidden charge density wave states (2016)

The functionality of computer memory elements is currently based on multi-stability, driven either by locally manipulating the density of electrons in transistors or by switching magnetic or ferroelectric order. Another possibility is switching between metallic and insulating phases by the motion of ions, but their speed is limited by slow nucleation and inhomogeneous percolative growth. Here we demonstrate fast resistance switching in a charge density wave system caused by pulsed current injection. As a charge pulse travels through the material, it converts a commensurately ordered polaronic Mott insulating state in 1T-TaS2 to a metastable electronic state with textured domain walls, accompanied with a conversion of polarons to band states, and concurrent rapid switching from an insulator to a metal. The large resistance change, high switching speed (30 ps) and ultralow energy per bit opens the way to new concepts in non-volatile memory devices manipulating all-electronic states.
Darstellung des 4‐Hydroxysemicarbazids und Cyclisierung zu Derivaten des 1,2,4‐Triazolon‐(5). 32. Mitt. über Hydroxylamin‐Derivate (1968)

Abstract Durch Hydroxylaminolyse von Äthoxycarbonylhydrazin wurde 4‐Hydroxysemicarbazid dargestellt und mit Orthoestern der Kohlen‐ und Ameisensäure in Derivate des 1,2,4‐Triazolon‐(5) übergeführt.
Azapsoralens. Synthesis of 8-azapsoralens (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAzapsoralens. Synthesis of 8-azapsoralensAndrew P. VanSickle and Henry RapoportCite this: J. Org. Chem. 1990, 55, 3, 895–901Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February 1990https://pubs.acs.org/doi/10.1021/jo00290a019https://doi.org/10.1021/jo00290a019research-articleACS PublicationsRequest reuse permissionsArticle Views705Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Empirical Measurements of Small Unmanned Aerial Vehicle Co-Axial Rotor Systems (2011)

Small unmanned aerial vehicles (SUAV) are beginning to dominate the area of intelligence, surveillance, target acquisition and reconnaissance (ISTAR) in forward operating battlefield scenarios. Of particular interest are vertical take-off and landing (VTOL) variants. Within this category co-axial rotor designs have been adopted due to their inherent advantages of size and power to weight ratio. The inter-rotor spacing attribute of a co-axial rotor system appears to offer insight into the optimum design characteristic. The H/D ratio has been cited as a significant factor in many research papers, but to date has lacked an empirical value or an optimal dimensionless condition. In this paper the H/D ratio of a SUAV has been explored thoroughly, reviewing the performance of these systems at incremental stages, the findings from this study have shown that a range of H/D ratios in the region of (0.41-0.65) is advantageous in the performance of SUAV systems. This finding lends itself to the theory of inter-rotor spacing as a non-dimensionally similar figure, which cannot be applied across a spectrum of systems; this could be attributed to the viscous losses of flight at low Reynolds Numbers (< 50,000).
Accurate collision response on polygonal meshes (2002)

We present a very general geometrical correction method for enforcing collisions and other geometrical constraints between polygonal mesh surfaces. It is based on a global resolution scheme that takes advantage of an efficient use of the conjugate gradient algorithm to find the appropriate displacement of the mesh vertices that would satisfy all the constraints simultaneously, and according to momentum conservation laws. This method has been implemented in a cloth simulation system along with a collision response model that enforces a minimum "thickness" distance between cloth surfaces, which can be efficiently integrated in an simulation scheme based on implicit integration. Some provided examples illustrate the efficiency of the method.