gebhart/patrepeval huggingface dataset:
Backcross (BC2‐BC4)‐Derived Fertile Plants from Glycine max and G. tomentella Intersubgeneric Hybrids (1993)

Wild perennial relatives of the soybean [ Glycine max (L.) Merr.] have not been utilized to broaden the genetic base of the crop. This study provides information on production, morphology, cytology, and breeding behavior of backcross (BC 2 to BC 4 )‐derived fertile plants from soybean (2 n = 40, genome GG) and G. tomentella Hayata (2 n = 78, genome DDEE). The main hurdle was to obtain BC~ plants ( G. max cv. Altona) × ( G. tomentella , Pl 483218)] → F 1 , 2 n = 59, genome GDE → colchicine treatment (CT) → 2 n = 118, GGDDEE × soybean cv. Clark 63 → BC 1 , 2, n = 76 (expected 2 n = 79). Three sterile BC 2 plants (2 n = 58, 2 n = 56, 2 n = 55) were produced. Procedures for immature seed‐rescue were utilized to obtain F, amphiploid, BC 1 and BC 2 plants. Soybean cv. Clark 63 was used as the recurrent parent in the backcrossing programs. The range of chromosome number among BC 3 plants was 2 n = 41 to 2 n = 52, and among BC 4 plants was 2 n = 40 to 64. A hypertriploid (2 n = 64) in BC 4 plant originated after fertilization of an unreduced egg ( n = 44) by a normal haploid ( n = 20) male gamete. Phenotypes of BC 3 and BC 4 plants were dissimilar but generally resembled closely to the soybean cv. Clark 63. We expect to isolate a series of aneuploid lines from BC 3 to BC 6 generations that may open up the path to introgress desired traits from wild perennial Glycine species to the cultivated soybean.
Solid-state switching for aircraft electric systems (1970)

An aircraft electric system designed around a solid-state approach offers many potential advantages over an electromechanical counterpart. These include higher reliability, longer life, more ruggedness, more versatility, and better compatibility. To achieve these advantages, however, it is not merely sufficient to replace electromechanical components with their solid-state equivalents. Here is one approach that has been tested in the laboratory and in aircraft during the past ten years-with success. Included is a report on an advanced system undergoing evaluation.
Folate status and adenomatous colonic polyps (1995)

We suggest that depressed red blood cell folate levels are associated with development of colonic adenomas.
Automated Online Monitoring of Distributed Applications through External Monitors (2006)

It is a challenge to provide detection facilities for large-scale distributed systems running legacy code on hosts that may not allow fault tolerant functions to execute on them. It is tempting to structure the detection in an observer system that is kept separate from the observed system of protocol entities, with the former only having access to the latter's external message exchanges. In this paper, we propose an autonomous self-checking monitor system, which is used to provide fast detection to underlying network protocols. The monitor architecture is application neutral and, therefore, lends itself to deployment for different protocols, with the rulebase against which the observed interactions are matched, making it specific to a protocol. To make the detection infrastructure scalable and dependable, we extend it to a hierarchical monitor structure. The Monitor structure is made dynamic and reconfigurable by designing different interactions to cope with failures, load changes, or mobility. The latency of the monitor system is evaluated under fault free conditions, while its coverage is evaluated under simulated error injections
Genome-Scale Analysis of Translation Elongation with a Ribosome Flow Model (2011)

We describe the first large scale analysis of gene translation that is based on a model that takes into account the physical and dynamical nature of this process. The Ribosomal Flow Model (RFM) predicts fundamental features of the translation process, including translation rates, protein abundance levels, ribosomal densities and the relation between all these variables, better than alternative ('non-physical') approaches. In addition, we show that the RFM can be used for accurate inference of various other quantities including genes' initiation rates and translation costs. These quantities could not be inferred by previous predictors. We find that increasing the number of available ribosomes (or equivalently the initiation rate) increases the genomic translation rate and the mean ribosome density only up to a certain point, beyond which both saturate. Strikingly, assuming that the translation system is tuned to work at the pre-saturation point maximizes the predictive power of the model with respect to experimental data. This result suggests that in all organisms that were analyzed (from bacteria to Human), the global initiation rate is optimized to attain the pre-saturation point. The fact that similar results were not observed for heterologous genes indicates that this feature is under selection. Remarkably, the gap between the performance of the RFM and alternative predictors is strikingly large in the case of heterologous genes, testifying to the model's promising biotechnological value in predicting the abundance of heterologous proteins before expressing them in the desired host.
Applying Megamodelling to Model Driven Performance Engineering (2009)

Model driven engineering (MDE) has to deal with an increasing number of interrelated modelling artifacts. The model driven performance engineering (MDPE) process is one concrete illustration of such a situation. This process applies MDE within the context of performance engineering in order to support domain experts, who generally lack the necessary performance expertise. In this paper, we demonstrate the use of megamodelling to manage the numerous artifacts involved in MDPE. Megamodelling enables the explicit modelling of the metadata on MDE artifacts, including possible relationships between those artifacts. Appropriate tool support enables different stakeholders to exploit this additional information. Applying the megamodelling to MDPE pointed out the need for an extension of the existing approach. Thus, the result of the paper is twofold: first, an extension of megamodelling is proposed, second the benefits of the approach are shown on the MDPE use case. We claim that the extension is not solely useful for the latter case, but has a more generic applicability.
Gleitringdichtungen an Kesseln für chemische Reaktionen (1964)

Abstract Für den gasdichten Abschluß der Rührerwellen an Kesseln für chemische Reaktionen läßt sich an Stelle der nachteiligen Stopfbuchse eine doppelte Gleitringdichtung mit Sperrmedium verwenden. Besondere Sorgfalt wird auf die Formgebung der Gleitringe, die Wahl der Gleitringwerkstoffe, die Lagerung der Rührerwelle und den Auibau des Kreislaufes für das Sperrmedium verwandt.
A Survey of Context Aware Web Service Discovery: From User's Perspective (2010)

Web service is one of the fundamental technologies in implementing Service Oriented Architecture (SOA) based applications. One of the essential challenges in web service based applications is how to find a set of suitable web service candidates with regard to a user's requirement. Currently most web service discovery systems have constrains on the content and format of submitted web service request. Therefore, during the information transformation from a user's real web service need to formalized request, some useful information is lost implicitly or explicitly. To understand the user's intention as much as possible, a lot of approaches have been proposed among them context aware methods have shown promising result. In this paper, we present an overview of the field of context aware web service discovery and try to classify current generation of those approaches into different categories. This paper also describes limitations of current context awareness in web service discovery and discusses possible applications that can enhance the overall discovery performance.
Development of the Patient Monitor Using Microprocessor(II) (1995)

In this paper, the patient monitor consisting of ECG/Respiration Amplification, Front end CPU, Main CPU, Main Controller, Video Amplifier, Display Controller, Waveform Generator, Bus & Power Supply, 8097 Processor was developed. This patient monitor measures the patient's states in the hospital such as elecctro-cardiography, respiration, blood pressurae and temperature. The control and processing methods based on micro-processor employ the flexibility, extensibility over other conventional system. The followings are incorporated in this system. First, ECG/RESP measures the respiration by impedence pneumography. Second, FECPU utilizes an Intel 8031 microcontroller. Third, Controller function originate from a LSI CRT controller.
Styryl dyes derived from bis boron diketonates (1985)

Abstract Bis boron diketonates are prepared from β‐diketones or o ‐acylphenols or naphthols with boron trichloride or boron tribromide. The bis boron diketonates that contain methyl groups reacted with some aromatic aldehydes, giving styryl dyes, most of which showed high extinction coefficients.
Structure and Function of Enzymes Adsorbed onto Single-Walled Carbon Nanotubes (2004)

We have examined the structure and function of two enzymes, alpha-chymotrypsin (CT) and soybean peroxidase (SBP), adsorbed onto single-walled carbon nanotubes (SWNTs). SBP retained up to 30% of its native activity upon adsorption, while the adsorbed CT retained only 1% of its native activity. Analysis of the secondary structure of the proteins via FT-IR spectroscopy revealed that both enzymes undergo structural changes upon adsorption, with substantial secondary structural perturbation observed for CT. Consistent with these results, AFM images of the adsorbed enzymes indicated that SBP retains its native three-dimensional shape while CT appears to unfold on the SWNT surface. This study represents the first in depth investigation of protein structure and function on carbon nanotubes, which is critical in designing optimal carbon nanotube-protein conjugates.
Novel method for reducing high-attenuation object artifacts in CT reconstructions (2002)

A new method to reduce the streak artifacts caused by high attenuation objects in CT images has been developed. The key part of this approach is a preprocessing procedure based on the raw projection data using an adaptive scaling-plus-filtering method. The procedure is followed by the conventional filtered-back projection to reconstruct artifact-reduced images. Phantom and clinical studies have demonstrated that the proposed method can effectively reduce the streak artifacts caused by high attenuation objects for different anatomical structures and metal materials while still faithfully reproduce the positions and dimensions of the metal objects. The visualization of tissue features adjacent to metal objects is greatly improved. The proposed method is computational efficient and can be easily adapted to the current commercial CT scanners.
<i>N</i> -Acetyl-Cysteine Decreases the Matrix-Degrading Capacity of Macrophage-Derived Foam Cells (1998)

Macrophage FCs are an abundant source of gelatinolytic activity that can be inhibited in vitro and in situ by NAC. This newly described action of antioxidant therapy might prove useful to inhibit matrix degradation and to improve vascular stability.
Secure Signature-Based Authenticated Key Establishment Scheme for Future IoT Applications (2017)

Internet of Things (IoT) is a network of all devices that can be accessed through the Internet. These devices can be remotely accessed and controlled using existing network infrastructure, thus allowing a direct integration of computing systems with the physical world. This also reduces human involvement along with improving accuracy and efficiency, resulting in economic benefit. The devices in IoT facilitate the day-to-day life of people. However, the IoT has an enormous threat to security and privacy due to its heterogeneous and dynamic nature. Authentication is one of the most challenging security requirements in the IoT environment, where a user (external party) can directly access information from the devices, provided the mutual authentication between user and devices happens. In this paper, we present a new signature-based authenticated key establishment scheme for the IoT environment. The proposed scheme is tested for security with the help of the widely used Burrows-Abadi-Needham logic, informal security analysis, and also the formal security verification using the broadly accepted automated validation of Internet security protocols and applications tool. The proposed scheme is also implemented using the widely accepted NS2 simulator, and the simulation results demonstrate the practicability of the scheme. Finally, the proposed scheme provides more functionality features, and its computational and communication costs are also comparable with other existing approaches.
The calcium-sensing receptor regulates calcium absorption in MDCK cells by inhibition of PMCA (2001)

Calcium transport across a monolayer of Madin-Darby canine kidney (MDCK) cells was measured in response to stimulation of the basal surface with calcium-sensing receptor (CaR) agonists. Stimulation of the CaR resulted in a time- and concentration-dependent inhibition of calcium transport but did not change transepithelial voltage or resistance. Inhibition of transport was not altered by pretreatment of cells with pertussis toxin but was blocked by the phospholipase C (PLC) inhibitor U-73122. To determine a potential mechanism by which the CaR could inhibit calcium transport, we measured activity of the plasma membrane calcium ATPase (PMCA). Stimulation of the CaR on the basal surface resulted in an inhibition of the PMCA in a concentration- and PLC-dependent manner. Thus stimulation of the CaR inhibits both calcium transport and PMCA activity through a PLC-dependent pathway. These studies provide the first direct evidence that calcium can inhibit its own transcellular absorption in a model of the distal tubule. In addition, they provide a potential mechanism for the CaR to inhibit calcium transport, inhibition of PMCA.
Repeated furrow formation from a single mitotic apparatus in cylindrical sand dollar eggs (1985)

The methods used previously to demonstrate the ability of a single mitotic apparatus to elicit multiple furrows involved considerable cell distortion and did not permit the investigator to control the positioning of the parts or to observe satisfactorily the early stages of furrow development. In this investigation, Echinarachnius parma eggs were confined in 82 microns i.d. transparent, silicone rubber-walled capillaries, and the mitotic apparatus was moved by pushing the poles inward with 55-microns-diameter glass balls. When the mitotic apparatus was shifted immediately after the furrow first appeared, a new furrow appeared in the normal relation to the new position in 1-2 minutes. The same mitotic apparatus could elicit up to 13 furrows as it was shifted back and forth by alternately pushing in the poles. The previous furrow regressed as the new furrow developed. The operations protracted the furrow establishment period to as long as 24.5 minutes after establishment of the first furrow. The characteristics of furrow regression were related to the distance the mitotic apparatus was moved. It is unlikely that regression was caused either by stress imposed on the surface or the removal of the mitotic apparatus from the vicinity of the furrow.
Alteration of plant growth and development by <i>Rhizobium nodA</i> and <i>nodB</i> genes involved in the synthesis of oligosaccharide signal molecules (1993)

The highly conserved Rhizobium nodulation genes nodABC are required to produce lipid‐linked chitooligosaccharide signal molecules which elicit nodule organogenesis in roots of leguminous plants. Recently, it has been shown that NodB deacetylates chitooligosaccharides at the non‐reducing terminus, so that the free amino group of the chitooligosaccharide backbone can then be acylated by a specific fatty acid. The Rhizobium NodA protein together with the nodB encoded chitooligosaccharide deacetylase are involved in generating small, heat‐stable compounds that stimulate mitosis in protoplasts derived from either legumes or other plant species. To test whether these gene products could play a role in regulation of plant development, we introduced and expressed the Rhizobium meliloti nodA and nodB genes singly or in combination under the control of diverse promoters in tobacco. Altered phenotypes correlating with nodA and nodB gene expression in transgenic plants indicate that tobacco contains the necessary substrates for the NodA and NodB proteins to produce signal molecules modulating plant growth and organ development.
Addressing DC Component in PLL and Notch Filter Algorithms (2011)

This paper presents a method for addressing the dc component in the input signal of the phase-locked loop (PLL) and notch filter algorithms applied to filtering and synchronization applications. The dc component may be intrinsically present in the input signal or may be generated due to temporary system faults or due to the structure and limitations of the measurement/conversion processes. Such a component creates low-frequency oscillations in the loop that cannot be removed using filters because such filters will significantly degrade the dynamic response of the system. The proposed method is based on adding a new loop inside the PLL structure. It is structurally simple and, unlike an existing method discussed in this paper, does not compromise the high-frequency filtering level of the concerned algorithm. The method is formulated for three-phase and single-phase systems, its design aspects are discussed, and simulations/experimental results are presented.
NEW DEVELOPMENT OF THE MAGNETIC METHOD FOR RESIDUAL STRESS TESTING (1998)

Experiments on specimens of mild steel and cast iron have been performed under vari-ous loading conditions.A modified formula is put forward to analyze the cruciform specimen which isoften used in magnetic methods for calibration.We assume that the relationship between the magneticoutput and strain is linear and a new four-coefficient method is deduced.Finally,the results of practi-cal applications are given.
Peptide Structure Modifications: Effect of Radical Species Generated by Controlled Gamma Ray Irradiation Approach (2013)

The present work aimed at evaluating the radiolysis effect upon a set of peptides, most of them involved in physiological functions. To generate reactive radical species, a Co(60) source (up to 15 kGy) was used for controlled gamma irradiation of some peptide solutions including derivatives attaching the stable free radical Toac (2,2,6,6-tetramethypiperidine-1-oxyl-4-amino-4-carboxylic acid). Regardless of the peptide sequence, a nonlinear and progressive degradation of a total of nine peptides was detected. The results were interpreted in the light of the half-life dose (D(1/2)) parameter which represents the dose necessary for 50% peptide structure degradation. The vasoactive angiotensin II (AngII)'s analogue Ang-(1-7) showed greater stability towards gamma ray radiation than bradykinin (BK), Toac(0)-BK, Pro(4)-BK (D(1/2) around 4 and 2 kGy, respectively) which decreased to about 0.5-1.0 kGy in the case of acetyl-α-melanocyte-stimulating hormone (Ac-α-MSH) and substance P (SP). In terms of peptide structural modifications, the data acquired from different analytical methods suggested a Phe to Tyr (or its ortho and/or meta isomers) transformation as a consequence of the hydroxyl moiety insertion. Noteworthy, this effect seemed to be position-dependent as only Phe located at or near the C-terminal portion seemed to display this transformation. In contrast, Met is comparatively more easily oxidized, thus allowing to conclude that gamma irradiation may induce a complex position and/or sequence-dependent effect on peptides. As previously applied for BK, some irradiated peptides were submitted to their by-products purification, indeed a complementary target of the present approach for development of uncommon analogues for further structure-function investigation.
Genomic analysis of a transposition-deletion variant of orf virus reveals a 3.3 kbp region of non-essential DNA (1995)

Restriction endonuclease analysis of the DNA extracted orf virus strain NZ2, which had been serially passaged in primary bovine testis cells, revealed a population of variants that had over-grown the wild-type virus. At least three distinct mutant forms were identified in which the right end of the genome had been duplicated and translocated to the left end, accompanied by deletions of sequences at the left end. Sequencing of a single variant isolated from the heterogeneous population revealed that recombination had occurred between non-homologous sequences. In this case, 6.6 kb of DNA at the left end of the genome had been replaced by 19.3 kb from the right end. The transposition resulted in the deletion at the left end of 3.3 kb of DNA encoding three genes and the terminal sequences of a fourth gene. The three genes completely deleted were a homologue of dUTPase, a gene that encodes a protein containing ankyrin-like repeats and a homologue of the 5K gene of the vaccinia virus WR strain. Experimental inoculation of sheep showed that the genes are also non-essential in vivo, but that the size of the lesion was reduced, compared with that induced by the wild-type, and resolved more rapidly.
Collision cross sections for protein ions (1993)

A method for the determination of cross sections for gas-phase protein ions, based on the energy loss of ions as they pass through a collision gas, is described. A simple model relates the energy loss to the number of collisions and hence the cross section. Results from a Monte Carlo model that support the validity of this approach are described. Experimental cross sections are reported for motilin, ubiquitin, cytochrome c, myoglobm, and bovine serum albumin. Cross sections range from approximately 800 Å(2) for motilin to approximately 14,000 Å(2) for bovine serum albumin and generally increase with the number of charges on the ion. Cytochrome c ions from aqueous solution show somewhat smaller cross sections than ions formed from solutions of higher organic content, suggesting that the gas-phase ions may retain some memory of their solution conformation.
Quinazolines and 1,4-Benzodiazepines. XVI.<sup>1</sup> Synthesis and Transformations of 5-Phenyl-1,4-benzodiazepine-2-thiones (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuinazolines and 1,4-Benzodiazepines. XVI.1 Synthesis and Transformations of 5-Phenyl-1,4-benzodiazepine-2-thionesG. A. Archer and L. H. SternbachCite this: J. Org. Chem. 1964, 29, 1, 231–233Publication Date (Print):January 1, 1964Publication History Published online1 May 2002Published inissue 1 January 1964https://pubs.acs.org/doi/10.1021/jo01024a511https://doi.org/10.1021/jo01024a511research-articleACS PublicationsRequest reuse permissionsArticle Views333Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts