gebhart/patrepeval huggingface dataset:
An improved frequency compensation technique for CMOS operational amplifiers (1983)

The commonly used two-stage CMOS operational amplifier suffers from two basic performance limitations due to the RC compensation network around the second gain stage. First, it provides stable operation for only a limited range of capacitive loads, and second, the power supply rejection shows severe degradation above the open-loop pole frequency. The technique described provides stable operation for a much larger range of capacitive loads, as well as much improved V/SUB BB/ power supply rejection over very wide bandwidths for the same basic operational amplifier circuit. The author presents a mathematical analysis of this new technique in terms of its frequency and noise characteristics followed by its implementation in all n-well CMOS process. Experimental results show 70-dB negative power supply rejection at 100 kHz and an input noise density of 58 nV/(Hz)/SUP 1/2/ at 1 kHz.
The implementation of clinical data management and statistics system (2017)

In this paper, a clinical data management and statistic system is implemented for authorized users such as doctors and medical researchers to manage clinical data. The system is able to inquiry patient particulars, diagnostic results, CT (Computerized Tomography) data and electrocardiogram (ECG) data, and it implements comparison function of Cardiodynamicsgram (CDG) data and statistic function for further analysis of medical research. The paper builds a stable and simple operating system based on GUI with MATLAB and SQL Server. The three-tier model which includes the storage platform of the system, abstract business logic layer and the operating interface, is utilized in this application. This system is very helpful for clinicians, as well as for researchers to do research on cardiovascular disease with the cardiovascular clinical data.
IFN-α promotes the rapid differentiation of monocytes from patients with chronic myeloid leukemia into activated dendritic cells tuned to undergo full maturation after LPS treatment (2003)

Chronic myelogenous leukemia (CML) is a malignant myeloproliferative disease arising from the clonal expansion of a stem cell expressing the bcr/abl oncogene. CML patients frequently respond to treatment with interferon-alpha (IFN-alpha), even though the mechanisms of the response remain unclear. In the present study, we evaluated the role of IFN-alpha in differentiation and activity of monocyte-derived dendritic cells (DCs) from CML patients as well as in modulation of the cell response to lipopolysaccharide (LPS). Treatment of CML monocytes with IFN-alpha and granulocyte-macrophage colony-stimulating factor (GM-CSF) resulted in the rapid generation of activated DCs (CML-IFN-DCs) expressing interleukin-15 (IL-15) and the antiapoptotic bcl-2 gene. These cells were fully competent to induce IFN-gamma production by cocultured autologous T lymphocytes and expansion of CD8(+) T cells. LPS treatment of CML-IFN-DCs, but not of immature DCs generated in the presence of IL-4/GM-CSF, induced the generation of CD8(+) T cells reactive against autologous leukemic CD34(+) cells. Altogether, these results suggest that (1) the generation of highly active monocyte-derived DCs could be important for the induction of an antitumor response in IFN-treated CML patients and (2) IFN-alpha can represent a valuable cytokine for the rapid generation of active monocyte-derived DCs to be utilized for vaccination strategies of CML patients.
The moral responsibility of the artist (1993)

Abstract: The deteriorating condition of our planet has reached a point which is undeniably critical. If we are to survive as a species and maintain a decent quality of life, long‐term goals and an active program of achieving them are certainly indicated. The creation of a society in a steady state of economic and ecological equilibrium is the only way to proceed. Not only would such a pursuit require determination, but it would be a challenge to our ingenuity and creativity. The transition from a growth‐ and consumer‐oriented society to a society geared toward equilibrium entails necessary changes in our values. The artist could and should assume a leading role in bringing about this change.
Generating High-Pressure Oxygen Electrolytically (1994)

Electrolytic cell generates oxygen directly at high pressure at point of use. System makes it unnecessary to use heavy, bulky air compressor or to ship compressed oxygen in heavy tanks. Produces hydrogen as byproduct, at pressure that may be different from that of oxygen, if desired. Cathode also barrier that lets gases collect at widely differing pressures.
The Absorption Cross Section for Light of the Silver Grains in Photographic Deposits (1963)

Estimations of projection area of silver grains in photographic deposits were made on photomicrographs as well as counts of grains per unit area. Density of the deposit was calculated from these data employing known formulae. These were found smaller by a factor of 2-3 when compared with densities measured in diffuse light. The absorption cross section of grains for light considerably greater than their projective area is concluded. The results are in agreement with those obtained by other authors, which were, however, interpreted in a different way.
Design and analysis of wearable pupillometer for autonomic neuropathy of diabetic patients (2014)

Diabetes is a familiar disease in modern society. In the early stage of diabetes, symptoms are unobvious, but they usually induce diabetic autonomic neuropathy or, worse, cardiovascular autonomic neuropathy. Pupillometers are effective instruments for observing human pupils. This article presents a novel wearable pupillometer design, without external light artifacts, and an embedded algorithm with blinking elimination, which investigates autonomic neuropathy through recording pupil dynamics triggered by an external sensitive invisible light source. The pupillometer is experimented on 36 healthy subjects and 10 diabetic patients under four different colors (white, red, green, and blue) as well as two different light intensities: 50 and 500 mcd. Ten parameters derived from pupil diameter, pupil response time, and pupil response speed will be evaluated for the healthy subjects and diabetic patients. The results show that three in four parameters related to pupil diameters, one in four related to light intensities, and one in two related to pupil response speed could have significant differences (p<0.05) between healthy subjects and diabetic patients. These parameters obtain over 85% sensitivity, 83% specificity, and 88% accuracy. The pupillometer is proven reliable, effective, portable, and inexpensive for diagnosing diabetes in an early stage.
Performance Metrics: How and When (2006)

Abstract This paper compares different classification performance metrics commonly used for environmental monitoring with remotely sensed satellite data and their associated error bounds. Discriminant functions were generated for three classifiers using common training data. Identical independent test data were classified by each discriminant function. The classified test values were evaluated by each performance metric. Each performance measure, its error bound, and its significance were computed. The performance measures were divided into three classes; those measures associated with contingency matrices, casewise comparisons, and ROC curves. The operation, results, and limitations of each metric are discussed.
Fibrosis progression under maintenance interferon in hepatitis C is better detected by blood test than liver morphometry (2011)

We evaluated whether quantitative measurements of liver fibrosis with recently developed diagnostics outperform histological staging in detecting natural or interferon-induced changes. We compared Metavir staging, morphometry (area and fractal dimension) and six blood tests in 157 patients with chronic hepatitis C from two trials testing maintenance interferon for 96 weeks. Paired liver biopsies and blood tests were available for 101 patients, and there was a significant improvement in Metavir activity and a significant increase in blood tests reflecting fibrosis quantity in patients treated with interferon when compared with controls - all per cent changes in histological fibrosis measures were significantly increased in F1 vs F2-4 stages only in the interferon group. For the whole population studied between weeks 0 and 96, there was significant progression only in the area of fibrosis (AOF) (P = 0.026), FibroMeter (P = 0.020) and CirrhoMeter (P = 0.003). With regards to dynamic reproducibility, agreement was good (r(ic) ≥ 0.72) only for Metavir fibrosis score, FibroMeter and CirrhoMeter. The per cent change in AOF was significantly higher than that of fractal dimension (P = 0.003) or Metavir fibrosis score (P = 0.015). CirrhoMeter was the only blood test with a change significantly higher than that of AOF (P = 0.039). AOF and two blood tests, reflecting fibrosis quantity, have high sensitivity and/or reproducibility permitting the detection of a small progression in liver fibrosis over two years. A blood test reflecting fibrosis quantity is more sensitive and reproducible than morphometry. The study also shows that maintenance interferon does not improve fibrosis, whatever its stage.
High Count Rate Neutron Spectrometry With Liquid Scintillation Detectors (2009)

Liquid scintillation detectors are widely used in nuclear/high-energy physics and nuclear fusion for spectral measurements in mixed radiation fields due to their compactness, fast response and neutron/gamma discrimination capabilities. The use of response functions evaluated for the specific system and of appropriate methods of data analysis allows such systems to be used as broadband spectrometers for photons and neutrons. System stability and ability to reach high throughput count rates are key challenges for several applications (e.g., neutron spectrometry for nuclear fusion devices), but standard analog electronics limits the operation of liquid scintillation neutron spectrometers to low count rates ( ~ 3 ldr 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> ) . The count rate capabilities of a liquid scintillation neutron spectrometer (NE213 detector) from the Physikalisch-Technische Bundesanstalt (PTB) has been extended up to ~ 4.2 ldr 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> , by coupling it to a digital acquisition system developed at ENEA-Frascati. Measurements have been carried out at PTB using gamma sources and accelerator-produced 2.5 MeV and 14 MeV neutrons. For 14 MeV neutron measurements, digital pulse height spectra (PHS) obtained at high count rates have been compared to PHS recorded with standard analog electronics. The results show that stable PHS (within 1%) can be obtained at high count rate despite the high sensitivity of the gain of photomultiplier tubes to count rate variations.
Transmethylation reactions of monomethyl and dimethylamine over montmorillonite in a flow system (1966)

Abstract In this work the transmethylation reactions of monomethylamine and dimethylamine were investigated under steady state conditions in a flow system. A differential reactor was employed with montmorillonite as the catalyst and the initial rates of these reactions were measured isothermally. Mass velocities through the reactor were sufficiently high to eliminate bulk stream diffusion to the catalyst interface as a possible rate‐controlling step of the reaction process. Pore diffusion was checked experimentally and shown to impose no limit on reaction rates. The controlling phenomena of the reactions were determined by applying the Freundlich and Langmuir adsorption isotherms to the experimental results in the form of initial reaction rate vs. average partial pressure of reactant at constant temperature. Velocity constants and Arrhenius equations for these controlling processes were also determined.
Single-Electron Transfer and Single-Electron Transfer Degenerative Chain Transfer Living Radical Polymerization (2009)

ADVERTISEMENT RETURN TO ISSUEReviewNEXTSingle-Electron Transfer and Single-Electron Transfer Degenerative Chain Transfer Living Radical PolymerizationBrad M. Rosen and Virgil Percec*View Author Information Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323* Corresponding author e-mail: [email protected]Cite this: Chem. Rev. 2009, 109, 11, 5069–5119Publication Date (Web):October 9, 2009Publication History Received19 January 2009Published online9 October 2009Published inissue 11 November 2009https://pubs.acs.org/doi/10.1021/cr900024jhttps://doi.org/10.1021/cr900024jreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views13136Altmetric-Citations832LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anions,Halogens,Inorganic compounds,Radical polymerization,Solvents Get e-Alerts
Effect of a novel repellent, acetylated glyceride, against sweet potato whitefly, <i>Bemisia tabaci</i> (Gennadius) (Hemiptera: Aleyrodidae) (2014)

With the aim of identifying safe control agents for whiteflies, we screened foods and food additives and observed that acetylated glyceride showed strong repellent activity against the sweet potato whitefly Bemisia tabaci. The acetylated glyceride (acetic and fatty acid esters of glycerol) has been used as food additives worldwide. The numbers of settled adults, courting pairs, and nymphs on host plant leaves were reduced by acetylated glyceride treatment. The highest control was attained with foliar treatment (0.2%, v/v) at 7-day intervals. Phytotoxicity to tomato plants was below the commercially acceptable level. The acetylated glyceride was harmless against four species of natural enemies examined.
Residential field site training project abstracts - 47th Batch Session: 2004-2005, 4th year MBBS students, CMC (1970)

DOI: 10.3329/jcmcta.v20i1.4943 Journal of Chittagong Medical College Teachers' Association 2009: 20(1):72-75
Clone region descriptors (2010)

Source code duplication, commonly known as code cloning , is considered an obstacle to software maintenance because changes to a cloned region often require consistent changes to other regions of the source code. Research has provided evidence that the elimination of clones may not always be practical, feasible, or cost-effective. We present a clone management approach that describes clone regions in a robust way that is independent from the exact text of clone regions or their location in a file, and that provides support for tracking clones in evolving software. Our technique relies on the concept of abstract clone region descriptors (CRDs), which describe clone regions using a combination of their syntactic, structural, and lexical information. We present our definition of CRDs, and describe a clone tracking system capable of producing CRDs from the output of different clone detection tools, notifying developers of modifications to clone regions, and supporting updates to the documented clone relationships. We evaluated the performance and usefulness of our approach across three clone detection tools and five subject systems, and the results indicate that CRDs are a practical and robust representation for tracking code clones in evolving software.
Feeding a brown midrib corn silage-based diet to growing beef steers improves growth performance and economic returns (2015)

Saunders, C. S., Yang, S. Y., Eun, J.-S., Feuz, D. M. and ZoBell, D. R. 2015. Feeding a brown midrib corn silage-based diet to growing beef steers improves growth performance and economic returns. Can. J. Anim. Sci. 95: 625–631. A feedlot experiment was performed to determine growth performance, ruminal fermentation characteristics, and economic returns for growing beef steers when fed a brown midrib corn silage-based total mixed ration (BMRT) compared with a conventional corn silage-based total mixed ration (CCST). Twenty-four Angus crossbred steers (initial body weight=258±23.2 kg) in individual pens were used in a completely randomized design (n=12). Intake of dry matter was not different between the treatments. Steers fed the BMRT tended to have greater average daily gain (1.54 vs. 1.42 kg d −1 ; P=0.09) and gain-to-feed ratio (0.165 vs. 0.146; P=0.07) compared with those fed the CCST. Feeding the BMRT increased total volatile fatty acid (VFA) concentration (P=0.01) compared with the CCST, while it decreased molar proportion of acetate (P<0.01), and increased propionate proportion (P=0.01), resulting in decreased acetate-to-propionate ratio compared with the CCST (P<0.01). Steers fed the BMRT increased feed margin (P=0.05) and net return (P=0.02) compared with those fed the CCST throughout the trial. Overall results of this study indicate that feeding the BMRT to growing beef steers enhanced ruminal fermentation and beneficially shifted VFA profiles, which contributed to improved growth and economic performance of steers.
Novel Thermosensitive IPN Hydrogel Having a Phase Transition Without Volume Change (2002)

A novel thermosensitive interpenetrating network (IPN) hydrogel was prepared from an aqueous solution of poly[3,3-dimethyl(methacryloyloxyethyl)propylammonium sulfonate] infiltrating a crosslinked sulfobetaine polymer, poly(2-acrylamido-2-methylpropylsulfonic acid). The IPN gel shows an upper critical solution temperature (UCST) depending on the molar ratio of the components and the presence of salt. In contrast to conventional gels, the IPN gel exhibits no volume phase transition after traversing the UCST.
Activation of NF-κB Is Involved in the Survival of Osteoclasts Promoted by Interleukin-1 (1998)

We previously reported that interleukin-1 (IL-1) promoted the survival of murine osteoclast-like cells (OCLs) formed in vitro and activated a transcription factor, NF-kappaB, of OCLs. The present study examined whether the activation of NF-kappaB is directly involved in the survival of OCLs promoted by IL-1. The expression of IL-1 type I receptor mRNA in OCLs was detected by the polymerase chain reaction amplification of reverse-transcribed mRNA. An electrophoretic mobility shift assay showed that IL-1 transiently activated NF-kappaB in the nuclei of the OCLs, and the maximal activation occurred at 30 min. The degradation of IkappaBalpha coincided with the activation of NF-kappaB in the OCLs. The immunocytochemical study revealed that p65, a subunit of NF-kappaB, was translocated from the cytoplasm into almost all of the nuclei of the OCLs within 30 min after IL-1 stimulation. The purified OCLs spontaneously died via apoptosis, and IL-1 promoted the survival of OCLs by preventing their apoptosis. The pretreatment of purified OCLs with proteasome inhibitors suppressed the IL-1-induced activation of NF-kappaB and prevented the survival of OCLs supported by IL-1. When OCLs were pretreated with antisense oligodeoxynucleotides to p65 and p50 of NF-kappaB, the expression of respective mRNAs by OCLs was suppressed, and the IL-1-induced survival of OCLs was concomitantly inhibited. These results indicate that IL-1 promotes the survival of osteoclasts through the activation of NF-kappaB.
Measurement of the Cobb angle on radiographs of patients who have scoliosis. Evaluation of intrinsic error. (1990)

To quantitate the intrinsic error in measurement, fifty anteroposterior radiographs of patients who had scoliosis were each measured on six separate occasions by four orthopaedic surgeons using the Cobb method. For the first two measurements (Set I), each observer selected the end-vertebrae of the curve; for the next two measurements (Set II), the end-vertebrae were pre-selected and constant. The last two measurements (Set III) were obtained in the same manner as Set II, except that each examiner used the same protractor rather than the one that he carried with him. The pooled results of all four observers suggested that the 95 per cent confidence limit for intraobserver variability was 4.9 degrees for Set I, 3.8 degrees for Set II, and 2.8 degrees for Set III. The interobserver variability was 7.2 degrees for Set I and 6.3 degrees for Sets II and III. The mean angles differed significantly between observers, but the difference was smaller when the observers used the same protractor.
Retinoblastoma-repression of E2F-dependent transcription depends on the ability of the retinoblastoma protein to interact with E2F and is abrogated by the adenovirus E1A oncoprotein (1992)

The product of the retinoblastoma tumor suppressor gene interacts with the transcription factor E2F. Two distinct types of interactions can be detected between the retinoblastoma gene product (Rb) and E2F. The first type involves an Rb-binding protein, RBP60. The Rb/E2F complex formed in the presence of RBP60 is able to bind DNA and migrates with a distinct mobility in gel retardation assays. The second type of Rb/E2F complex is seen in the absence of RBP60. This second type of Rb/E2F complex does not form a band-shift complex in gel retardation assays and its formation results in an apparent inhibition or loss of the DNA binding activity of E2F. Using a series of Rb-mutants we show that these two types of Rb/E2F complexes depend on common domains of the Rb protein. The T/E1A-binding region as well as the carboxyl-terminus of the Rb protein are critical for these two types of Rb/E2F interactions. We also show that the retinoblastoma protein represses the E2F-dependent transcription, and this Rb-repression of the E2F-dependent transcription depends on the ability of Rb to interact with E2F. Moreover, the adenovirus E1A gene product, which binds Rb, counteracts the Rb-repression and restores E2F-dependent transcription.
Equal Protection and the New Rational Basis Test: the Mentally Retarded are not Second Class Citizens in Cleburne (1986)

Recently, the Fifth Circuit held that classifications involving the mentally retarded were quasi-suspect and should be reviewed under a heightened scrutiny analysis. The Supreme Court reversed that holding but granted the retarded a remedy by applying a more genuine scrutiny under the rational basis test. The Court's decision in City of Cleburne, Texas v. Cleburne Living Center, Inc. raises the question whether the Court intends to apply an increased level of scrutiny under the rational basis test or whether this case merely represents another ad hoc decision made on the horns of a dilemma. This Note discusses the uncertain impact of Cleburne on the retarded and similarly situated individuals.
Haplotype reconstruction from genotype data using Imperfect Phylogeny (2004)

The algorithm is available via a Web server at http://www.calit2.net/compbio/hap/