gebhart/patrepeval huggingface dataset:
Using Quantitative Trait Loci Results to Discriminate Among Crosses on the Basis of Their Progeny Mean and Variance (2007)

To develop inbred lines, parents are crossed to generate segregating populations from which superior inbred progeny are selected. The value of a particular cross thus depends on the expected performance of its best progeny, which we call the superior progeny value. Superior progeny value is a linear combination of the mean of the cross's progeny and their standard deviation. In this study we specify theory to predict a cross's progeny standard deviation from QTL results and explore analytically and by simulation the variance of that standard deviation under different genetic models. We then study the impact of different QTL analysis methods on the prediction accuracy of a cross's superior progeny value. We show that including all markers, rather than only markers with significant effects, improves the prediction. Methods that account for the uncertainty of the QTL analysis by integrating over the posterior distributions of effect estimates also produce better predictions than methods that retain only point estimates from the QTL analysis. The utility of including estimates of a cross's among-progeny standard deviation in the prediction increases with increasing heritability and marker density but decreasing genome size and QTL number. This utility is also higher if crosses are envisioned only among the best parents rather than among all parents. Nevertheless, we show that among crosses the variance of progeny means is generally much greater than the variance of progeny standard deviations, restricting the utility of estimates of progeny standard deviations to a relatively small parameter space.
The role of cathelicidins in the innate host defenses of mammals. (2005)

The cathelicidin peptides comprise one of several families of antimicrobial peptides that are found in neutrophils and epithelia as components of the early host defenses of mammals against infection. All cathelicidin family members are synthesized and stored in cells as two-domain proteins. These are split on demand to produce a cathelin protein and an antimicrobial peptide. Accumulating evidence indicates that both the cathelin portion and the C-terminal peptide exert biological activities connected with host protection. This review presents an overview of the structure and biology of cathelicidins and discusses recent progress in cathelicidin research with emphasis on the functional properties and role in host defense of the human cathelicidin hCAP18/LL-37. Although investigators initially concentrated their attention on antibiotic activity, it is becoming clear now that LL-37 is a multifunctional molecule that may mediate various host responses, and thus represents an essential component of the innate immune system in humans.
Comparative study and improvement of current cell micro-patterning techniques (2007)

The original micropatterning technique on gold, although very efficient, is not accessible to most biology labs and is not compatible with their techniques for image acquisition. Other solutions have been developed on silanized glass coverslips. These methods are still hardly accessible to biology labs and do not provide sufficient reproducibility to become incorporated in routine biological protocols. Here, we analyzed cell behavior on micro-patterns produced by various alternative techniques. Distinct cell types displayed different behavior on micropatterns, while some were easily constrained by the patterns others escaped or ripped off the patterned adhesion molecules. We report methods to overcome some of these limitations on glass coverslips and on plastic dishes which are compatible with our experimental biological applications. Finally, we present a new method based on UV crosslinking of adhesion proteins with benzophenone to easily and rapidly produce highly reproducible micropatterns without the use of a microfabricated elastomeric stamp.
ChemInform Abstract: Synthetic Chemistry for Ultrapure, Processable, and High‐Mobility Organic Transistor Semiconductors (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Vehicle attitude estimation in adverse weather conditions using a camera, a GPS and a 3D road map (2011)

We investigate the scenario of a vehicle equipped with a camera and a GPS driving on a road whose 3D map is known. We focus on the case of a road under fog or/and snow conditions. The GPS is used to estimate the vehicle pose and yaw and then the 3D road map is projected onto the camera image. The vehicle pitch and roll angles are then refined by fitting the projected road to detected road markings. Finally, we discuss the pros and cons of the obtained road registrations in the images and of the vehicle pitch-roll estimates, with respect to the vehicle dynamics and the driving environment, in adverse weather conditions.
Grid-gated photomultiplier photometer with subnanosecond time response (1980)

A grid-gated photomultiplier has been used in the construction of a subnanosecond-time-resolved photometer. The photocathode is gated on during a sampling window which occupies 4 ns of an 8-ns mode-locked ion laser cycle. The 0.5-ns rise-time sampling window is derived from the mode-locker drive signal and can be adjusted in phase relative to the incident laser light pulses. By resolving scattered light pulses from long-lived fluorescence, the photometer affords a 20-fold reduction in scattered light interfering with photobleaching recovery measurements of low-level fluorescence. Moreover, it has permitted the time-domain measurement with dc circuitry of fluorescence lifetimes as short as 0.7 ns. This time response is achieved using a photomultiplier which, in the absence of grid gating, exhibits an anode pulse rise time of 18 ns. Additional applications of this device and of a related narrow-window sampling photometer currently under development are discussed.
Strategies for Pathogen Biocontrol Using Lactic Acid Bacteria and Their Metabolites: A Focus on Meat Ecosystems and Industrial Environments (2017)

The globalization of trade and lifestyle ensure that the factors responsible for the emergence of diseases are more present than ever. Despite biotechnology advancements, meat-based foods are still under scrutiny because of the presence of pathogens, which causes a loss of consumer confidence and consequently a fall in demand. In this context, Lactic Acid Bacteria (LAB) as GRAS organisms offer an alternative for developing pathogen-free foods, particularly avoiding <i>Listeria monocytogenes</i>, with minimal processing and fewer additives while maintaining the foods' sensorial characteristics. The use of LAB strains, enabling us to produce antimicrobial peptides (bacteriocins) in addition to lactic acid, with an impact on quality and safety during fermentation, processing, and/or storage of meat and ready-to-eat (RTE) meat products, constitutes a promising tool. A number of bacteriocin-based strategies including the use of bioprotective cultures, purified and/or semi-purified bacteriocins as well as their inclusion in varied packaging materials under different storage conditions, have been investigated. The application of bacteriocins as part of hurdle technology using non-thermal technologies was explored for the preservation of RTE meat products. Likewise, considering that food contamination with <i>L. monocytogenes</i> is a consequence of the post-processing manipulation of RTE foods, the role of bacteriocinogenic LAB in the control of biofilms formed on industrial surfaces is also discussed.
Source encoding using syntactic information source models (1988)

The use of syntactic information source models for the source encoding (data compression) of messages is described. Syntactic models formulated using context-free grammars augmented with derivation step probabilities are considered. Using an arithmetic coder as the low-level encoding unit, it is shown how practical encoding systems can be constructed from such models. Application of the techniques to the encoding of syntactically correct Pascal computer programs is described, and additional techniques including the use of symbol tables are introduced. The resultant syntactic encoders achieve compression of Pascal programs approaching 90%.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Fabrication and characterization of high-flatness mesa-etched silicon nitride x-ray masks (1991)

To realize a technology for x-ray nanolithography (&lt;100 nm features), which is compatible with manufacturing, a number of mask design requirements must be met that are unrelated to patterning, repair, and alignment. These include high-flatness membranes and support structures so that mask-wafer gaps less than 10 μm can be achieved without risk of damage, and a rigid mask frame to avoid problems of distortion during handling. The membrane material should be compatible with semiconductor-processing, possess high strength, be radiation hard, and be transparent to light for alignment purposes. Details of a mask architecture that meets these requirements will be described.
A microcontroller-based failsafe for single photon counting modules (2003)

Avalanche photodiode-based single photon counting modules (SPCMs) can be damaged by exposure to excessive light levels. A flexible and inexpensive failsafe is presented which has been shown to protect SPCMs from light levels far exceeding the damage threshold.
Potential Applications of Human Embryonic Stem Cell‐Derived Cardiomyocytes (2004)

The recent establishment of the human embryonic stem cell lines and the demonstration of their ability to differentiate in vitro to cardiomyocytes brings a unique promise to both basic and clinical research. The present report describes the characteristics of the human embryonic stem cell lines and focuses on the structural and functional properties of their cardiomyocyte derivatives. In addition, the possible signals and cues involved in the commitment and early differentiation of cardiomyocytes will be discussed. Finally, the potential applications of this unique differentiating system in several research and clinical areas are discussed, with special emphasis on the steps required to fully harness their potential for myocardial regeneration strategies.
Reactions of Uracil and Cytosine Derivatives with Sodium Bisulfite (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Uracil and Cytosine Derivatives with Sodium BisulfiteRobert. Shapiro, Robert E. Servis, and Marvin. WelcherCite this: J. Am. Chem. Soc. 1970, 92, 2, 422–424Publication Date (Print):January 1, 1970Publication History Published online11 December 2002Published inissue 1 January 1970https://doi.org/10.1021/ja00705a626Request reuse permissionsArticle Views1278Altmetric-Citations230LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (422 KB) Get e-Alertsclose Get e-Alerts
Normalized Cross-Correlation Based Fingerprint Matching (2008)

To perform fingerprint matching based on the number of corresponding minutia pairings, has been in use for quite sometime. But this technique is not very efficient for recognizing the low quality fingerprints. To overcome this problem, some researchers suggest the correlation technique which provides better result. Use of correlation-based methods is increasing day-by-day in the field of biometrics as it provides better results. In this paper, we propose normalized cross-correlation technique for fingerprint matching to minimize error rate as well as reduce the computational effort than the minutiae matching method. The EER (equal error rate) obtained from result till now with minutiae matching method is 3%, while that obtained for the method proposed in this paper is approx 2% for all types of fingerprints in combined form.
Monocular 3D Human Pose Estimation by Predicting Depth on Joints (2017)

This paper aims at estimating full-body 3D human poses from monocular images of which the biggest challenge is the inherent ambiguity introduced by lifting the 2D pose into 3D space. We propose a novel framework focusing on reducing this ambiguity by predicting the depth of human joints based on 2D human joint locations and body part images. Our approach is built on a two-level hierarchy of Long Short-Term Memory (LSTM) Networks which can be trained end-to-end. The first level consists of two components: 1) a skeleton-LSTM which learns the depth information from global human skeleton features; 2) a patch-LSTM which utilizes the local image evidence around joint locations. The both networks have tree structure defined on the kinematic relation of human skeleton, thus the information at different joints is broadcast through the whole skeleton in a top-down fashion. The two networks are first pre-trained separately on different data sources and then aggregated in the second layer for final depth prediction. The empirical e-valuation on Human3.6M and HHOI dataset demonstrates the advantage of combining global 2D skeleton and local image patches for depth prediction, and our superior quantitative and qualitative performance relative to state-of-the-art methods.
Multiple-subcarrier optical communication systems with subcarrier signal point sequence (2004)

We propose a multiple-subcarrier (MS) optical communication system with subcarrier signal point sequence (SSPS). We use the SSPS having the large minimum value and the large Euclidean distances, so that the required d.c. bias is minimized and the error rate performance is improved. Note that in the proposed systems, the signal points having the larger minimum value are selected, while the signal points having lower peak to mean envelope power ratio (PMEPR) are selected in orthogonal frequency division multiplexing (OFDM) systems. Therefore, the signal point sequences good for OFDM with phase shifting by /spl pi/ radian are not necessarily good ones for MS optical communication systems. We show that the normalized power requirement and normalized bandwidth requirement of the MS-SSPS are smaller than those of the conventional MS systems.
High-power spatially coherent operation of unstable resonator semiconductor lasers with regrown lens trains (1992)

We have obtained high-power spatially coherent operation in wide-stripe InGaAs/GaAs/AlGaAs semiconductor lasers using a monolithic unstable resonator [consisting of diverging lens elements incorporated above an asymmetric graded-index separate confinement heterostructure (AGRIN-SCH)]. The fabrication involves MOCVD regrowth after wet-chemical etching of lens-like patterns in a GaAs layer above the active region. Pulsed output powers of 175 and 490 mW have been obtained in 170- and 100-μm-wide lasers, respectively, with spatial coherence in the near field exceeding 60%. We observe good lateral mode discrimination up to 3.5 times threshold in the 100-μm stripes with a round-trip magnification of 6.4.
Real-Time Bidding with Multi-Agent Reinforcement Learning in Display Advertising (2018)

Real-time advertising allows advertisers to bid for each impression for a visiting user. To optimize specific goals such as maximizing revenue and return on investment (ROI) led by ad placements, advertisers not only need to estimate the relevance between the ads and user's interests, but most importantly require a strategic response with respect to other advertisers bidding in the market. In this paper, we formulate bidding optimization with multi-agent reinforcement learning. To deal with a large number of advertisers, we propose a clustering method and assign each cluster with a strategic bidding agent. A practical Distributed Coordinated Multi-Agent Bidding (DCMAB) has been proposed and implemented to balance the tradeoff between the competition and cooperation among advertisers. The empirical study on our industry-scaled real-world data has demonstrated the effectiveness of our methods. Our results show cluster-based bidding would largely outperform single-agent and bandit approaches, and the coordinated bidding achieves better overall objectives than purely self-interested bidding agents.
Direct Capture of Plasma Factor VIII:C by Ion Exchange Chromatography (1994)

An ion exchange medium, DEAE-Fractogel 650M, can be used to capture factor VIII (FVIII) directly from plasma. Previous reports have focussed on the use of this medium to capture FVIII from cryoprecipitate. In this report, citrate phosphate dextrose plasma was batch-stirred with DEAE-Sephadex A50, filtered, diluted, loaded onto a column packed with DEAE-Fractogel TSK 650M, and chromatographed. Most of the unwanted proteins flowed through the gel unadsorbed. Bound FVIII was eluted by increasing the ionic strength of the buffer. A citrate- based buffer gave an overall FVIII:C yield of 670 IU/kg plasma with a specific activity of 0.68 IU FVIII:C/mg protein. This process gave a higher yield of FVIIEC but significantly more prothrombin complex factors than cryoprecip- itation. This method is a promising alternative to cryoprecipitation of FVIII.
A new method of magnetostrictivity and magnetostriction measurement (1989)

The magnetostrictivity (d) and magnetostriction ( lambda ) of high coupling magnetomechanical amorphous ribbons and wires are determined without the use of a direct magnetomechanical measurement. The method relies on an easily measured magnetic property (permeability) of the magnetostrictive material obtained under the conditions of constant stress and constant strain ( mu /sup c/). The magnetomechanical nature of the measurement enters through mu /sup c/. Experimental results are compared to predictions made on the basis of the single-vector magnetization rotation model. The effect of demagnetization on the magnetostrictivity and coupling factor is also calculated for long thin ribbons and wires.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Phytoalexin Accumulation in Omithopus sativus as a Response to Elicitor Treatment (1993)

An isoflavanoid derivative has been isolated as a phytoalexin from intact plants and cell suspension cultures of Ornithopus sativus after treatment with CuSO 4 , yeast elicitor, or a spore suspension of Colletotrichum trifolii. Based on its physical and spectroscopic properties the substance was identified as glabridin. After induction, the transient in crease in the content of this phytoalex in was preceded by a transient increase in the activities of PAL and CHS.
The Effect of Continuous Epidural Block in Lumbago and Sciatica (1995)

Extradural block is a form of treatment described as early as the beginning of the present centuries. It has since had positive criticism from a number of authors in different countries. Epidural injections of steroids with or without local anesthetic have become an occasional method of conservative treatment in sciatica & lumbago, especially in acute case. We assess the results of continuous epidural block with steroids and local anesthetics in sciatica & lumbago. From July 1994 to June 1995, we treated 46 case of lumbago and sciatica using continuous epidural block with steroids and local anesthetics. After placement of 17-Gauge Tuohy needle in the epidural space by the technique of loss of resistance, 0.25% bupivacaine 5 cc and triamcinolone 40 mg was administered and then epidural catheter was placed and connected to multiday infusor(Paragon) using 1% lidocaine with continuous infusion rate of 1 ml/hour. Usually, the catheter was removed after 1~2 weeks and then treated with the physical therapy. At the time of patient's discharge, 69.5% of all cases showed excellent or good results. Of particular note, 26 of the 46 cases were followed up by telephone. At present, in using Of particular note, 26 of the 46 cases were followed up by telephone. At present, in using continuous epidural block procedure, a relief in symptoms showed in 65.5% of these 26 cases. Continuous epidural block provides shortening of the recovery time from pain, avoidance of long period bed rest and early physical therapy and exercise. Therefore, continuous epidural block is simple and safe in the treatment of lumbago and sciatica, especially in acute phase.