gebhart/patrepeval huggingface dataset:
A Rationale for the Large Breathing of the Porous Aluminum Terephthalate (MIL‐53) Upon Hydration (2004)

Aluminum 1,4-benzenedicarboxylate Al(OH)[O(2)C-C(6)H(4)-CO(2)]. [HO(2)C-C(6)H(4)-CO(2)H](0.70) or MIL-53 as (Al) has been hydrothermally synthesized by heating a mixture of aluminum nitrate, 1,4-benzenedicarboxylic acid, and water, for three days at 220 degrees C. Its 3 D framework is built up of infinite trans chains of corner-sharing AlO(4)(OH)(2) octahedra. The chains are interconnected by the 1,4-benzenedicarboxylate groups, creating 1 D rhombic-shaped tunnels. Disordered 1,4-benzenedicarboxylic acid molecules are trapped inside these tunnels. Their evacuation upon heating, between 275 and 420 degrees C, leads to a nanoporous open-framework (MIL-53 ht (Al) or Al(OH)[O(2)C-C(6)H(4)-CO(2)]) with empty pores of diameter 8.5 A. This solid exhibits a Langmuir surface area of 1590(1) m(2)g(-1) together with a remarkable thermal stability, since it starts to decompose only at 500 degrees C. At room temperature, the solid reversibly absorbs water in its tunnels, causing a very large breathing effect and shrinkage of the pores. Analysis of the hydration process by solid-state NMR ((1)H, (13)C, (27)Al) has clearly indicated that the trapped water molecules interact with the carboxylate groups through hydrogen bonds, but do not affect the hydroxyl species bridging the aluminum atoms. The hydrogen bonds between water and the oxygen atoms of the framework are responsible for the contraction of the rhombic channels. The structures of the three forms have been determined by means of powder X-ray diffraction analysis. Crystal data for MIL-53 as (Al) are as follows: orthorhombic system, Pnma (no. 62), a = 17.129(2), b = 6.628(1), c = 12.182(1) A; for MIL-53 ht (Al), orthorhombic system, Imma (no. 74), a = 6.608(1), b = 16.675(3), c = 12.813(2) A; for MIL-53 lt (Al), monoclinic system, Cc (no. 9), a = 19.513(2), b = 7.612(1), c = 6.576(1) A, beta = 104.24(1) degrees.
Repeatability of magnetic-field driven self-assembly of magnetic nanoparticles (2011)

We demonstrate 27 ± 11 nm precision using stray magnetic fields from hard disk drive media to assemble 13 nm Fe3O4 magnetic nanoparticles in de-ionized water. By aligning the substrate polishing striations found in atomic force microscopy (AFM) images of the media topography, we determine the variance of multiple nanoparticle coatings. The widths of the assembled features are ∼200 nm, and features are always distinct when separated by a median distance of 500 nm. As these nanoparticles predictably follow the field gradient, trapped nanoparticles offer a nanoscale precision metrology for mapping the stray magnetic fields of high density media using AFM. Thus our approach offers a means to verify magnetic force microscopy images, as well as a method for nanomanufacturing complex nanoparticle assemblies.
Development of autoimmune hepatitis–like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator (2008)

Our results indicate that BTLA plays an important role in the maintenance of immune tolerance and the prevention of autoimmune diseases.
Integrated daylight harvesting and occupancy detection using digital imaging (2008)

This paper describes a proof-of-concept implementation that uses a high dynamic range CMOS video camera to integrate daylight harvesting and occupancy sensing functionalities. It has been demonstrated that the proposed concept not only circumvents several drawbacks of conventional lighting control sensors, but also offers functionalities that are not currently achievable by these sensors. The prototype involves three algorithms, daylight estimation, occupancy detection and lighting control. The calibrated system directly estimates luminance from digital images of the occupied room for use in the daylight estimation algorithm. A novel occupancy detection algorithm involving color processing in YCC space has been developed. Our lighting control algorithm is based on the least squares technique. Results of a daylong pilot test show that the system i) can meet different target light-level requirements for different task areas within the field-of-view of the sensor, ii) is unaffected by direct sunlight or a direct view of a light source, iii) detects very small movements within the room, and iv) allows real-time energy monitoring and performance analysis. A discussion of the drawbacks of the current prototype is included along with the technological challenges that will be addressed in the next phase of our research.
Correction of B<sub>0</sub> eddy current effects in spiral MRI (2018)

The proposed eddy current correction framework was effective in mitigating the effects of residual B<sub>0</sub> and linear eddy currents. Any spiral acquisition should take residual eddy currents into account. This is particularly important in spiral-in/out acquisitions.
A Hybrid Supercapacitor based on Porous Carbon and the Metal‐Organic Framework MIL‐100(Fe) (2014)

Abstract Composite supercapacitor electrodes based on carbon nanotubes, carbon black, and a metal–organic framework with iron(III) coordination centers [MIL‐100(Fe), MIL‐88B(Fe), or MIL‐53(Fe)] were prepared and tested with several aqueous electrolytes. A correlation between hydrated ion size and the electric response of the electrodes was found, which sheds light on how these materials work as energy‐storage devices. MIL‐100(Fe) shows the most promising results, and the capacitance obtained with the samples in the solutions used is higher than that of a mixture of carbon and nanotubes in the same solution. Unfortunately, shortcomings due to reductive dissolution still hamper the long‐term cyclability of the electrodes.
Aminoglycoside Resistance in<i>Pseudomonas aeruginosa</i> (2005)

Aminoglycosides ([35][1]) are a vital component of antipseudomonal chemotherapy implicated in the treatment of a variety of infections ([9][2], [45][3]), particularly pulmonary infections in cystic fibrosis (CF) patients ([22][4]). These agents are bactericidal and exhibit synergy with other
Quantum Nondemolition Detection of a Propagating Microwave Photon (2014)

The ability to nondestructively detect the presence of a single, traveling photon has been a long-standing goal in optics, with applications in quantum information and measurement. Realizing such a detector is complicated by the fact that photon-photon interactions are typically very weak. At microwave frequencies, very strong effective photon-photon interactions in a waveguide have recently been demonstrated. Here we show how this type of interaction can be used to realize a quantum nondemolition measurement of a single propagating microwave photon. The scheme we propose uses a chain of solid-state three-level systems (transmons) cascaded through circulators which suppress photon backscattering. Our theoretical analysis shows that microwave-photon detection with fidelity around 90% can be realized with existing technologies.
Millimeter-Wave Wireless LAN and Its Extension toward 5G Heterogeneous Networks (2015)

Millimeter-wave (mmw) frequency bands, especially 60GHz unlicensed band, are considered as a promising solution for gigabit short range wireless communication systems. IEEE standard 802.11ad, also known as WiGig, is standardized for the usage of the 60GHz unlicensed band for wireless local area networks (WLANs). By using this mmw WLAN, multi-Gbps rate can be achieved to support bandwidth-intensive multimedia applications. Exhaustive search along with beamforming (BF) is usually used to overcome 60GHz channel propagation loss and accomplish data transmissions in such mmw WLANs. Because of its short range transmission with a high susceptibility to path blocking, multiple number of mmw access points (APs) should be used to fully cover a typical target environment for future high capacity multi-Gbps WLANs. Therefore, coordination among mmw APs is highly needed to overcome packet collisions resulting from un-coordinated exhaustive search BF and to increase total capacity of mmw WLANs. In this paper, we firstly give the current status of mmw WLANs with our developed WiGig AP prototype. Then, we highlight the great need for coordinated transmissions among mmw APs as a key enabler for future high capacity mmw WLANs. Two different types of coordinated mmw WLAN architecture are introduced. One is distributed antenna type architecture to realize centralized coordination, while the other is autonomous coordination with the assistance of legacy Wi-Fi signaling. Moreover, two heterogeneous network (HetNet) architectures are also introduced to efficiently extend the coordinated mmw WLANs to be used for future 5th Generation (5G) cellular networks.
Constitution and biosynthesis of capsaicin (1968)

Capsaicin, the crystalline pungent principle of Capsicum annuum, has been shown to be a mixture of at least five closely related vanillyl amides. Phenylalanine, various hydroxylated cinnamic acids, and vanillylamine, all labelled with tritium in the aromatic ring, were incorporated biosynthetically into the C6–C1 unit of capsaicin. Tyrosine was incorporated much less efficiently than phenylalanine. The radioactive capsaicin mixture derived biosynthetically from phenylalanine was found to contain most of the activity in the minor, saturated components.
Structural Graph Indexing for Mining Complex Networks (2010)

Systems such as proteins, chemical compounds, and the Internet are being modeled as complex networks to identify local and global characteristics of the system. In many instances, these graphs are very large in size presenting challenges in their analysis. Hence, graph indexing techniques are developed to enhance various graph mining algorithms. In this paper, we propose a new Structural Graph Indexing (SGI) technique that does not limit the number of nodes in indexing to provide an alternative tool for graph mining algorithms. As indexing feature, we use common graph structures, namely, star, complete bipartite, triangle and clique, that frequently appear in protein, chemical compound, and Internet graphs. Note that, SGI lists all substructures matching structure formulations and other graph structures can be identified and added to the SGI.
Charge transport in nickel phthalocyanine crystals. I. Ohmic and space-charge-limited currents in vacuum ambient (1977)

Measurements of the temperature dependence of ohmic and space-charge-limited (SCL) bulk currents flowing in the c' direction in crystals of beta -nickel phthalocyanine in vacuum ambient have been used to locate the statistically important energy levels and their state densities in this molecular solid. Two temperature-induced changes in the activation energy E for ohmic conduction have been observed. From these findings the presence is deduced of a discrete electron level 0.43 eV below the conduction band, with a state density of 5*1025 m-3, and a hole level 0.64 eV above the valence band, having a state density of 3*1018 m-3. The thermal band gap is 1.63 eV. Measurement of the thermoelectric power showed that NiPc is n-type over the temperature range 325-425K, the excess donor concentration being 8*1017 m-3. The room temperature electrical conductivity is 1.0*10-3 Omega -1 m-1.
Obsessive-compulsive disorder: diagnosis and treatment. (1999)

Obsessive-compulsive disorder (OCD) is a chronic, disabling anxiety disorder that is characterized by recurrent obsessions and uncontrolled compulsions such as repetitive behavioral or mental acts that are performed in response to an obsession. OCD often occurs comorbidly with a number of depressive and anxiety disorders. In addition, patients with OCD suffer significant personal and social morbidity and may have difficulty maintaining a job, finishing school, and developing relationships. The backbone of pharmacologic treatment for OCD is a 10- to 12-week trial with a selective serotonin reuptake inhibitor (SSRI) in adequate doses. In most cases, treatment should be initiated with an SSRI because of the superior safety, tolerability, and equivalent efficacy of this class of drugs compared with clomipramine. When dealing with patients who do not respond to one SSRI, effective alternatives include switching to a different SSRI, combining another medication or behavioral therapy with SSRI therapy, considering novel or experimental drug treatments, or employing nonpharmacologic biological approaches, such as electroconvulsive therapy, neurosurgery, or repetitive transcranial magnetic stimulation. This article provides an update on the diagnosis and medical management of OCD and will discuss guidelines for the use of SSRIs and novel approaches for managing treatment-refractory patients.
Parametric estimation of time varying baselines in airborne interferometric SAR (2002)

A method for estimation of time varying spatial baselines in airborne interferometric synthetic aperture radar (SAR) is described. The range and azimuth distortions between two images acquired with a non-linear baseline are derived. A parametric model of the baseline is then, in a least square sense, estimated from image shifts obtained by cross correlation of numerous small patches throughout the image. The method has been applied to airborne EMISAR imagery from the 1995 campaign over the Storstrommen Glacier in North East Greenland conducted by the Danish Center for Remote Sensing. This has reduced the baseline uncertainties from several meters to the centimeter level in a 36 km scene. Though developed for airborne SAR the method can easily be adopted to satellite data.
A guanine nucleotide-sensitive adenylate cyclase in the yeast Saccharomyces cerevisiae. (1983)

Adenylate cyclase in particulate extracts of Saccharomyces cerevisiae utilized either MnATP or MgATP as substrate. A mutation in the CYR1 gene, which codes for the catalytic unit of yeast adenylate cyclase (Matsumoto, K., Uno, I., and Ishikawa, T. (1983) Cell 32, 417-423), eliminated utilization of both MgATP and MnATP, indicating that a single enzyme was responsible for both activities. GTP and guanylyl-5'-imidodiphosphate stimulated yeast adenylate cyclase, while a GDP analog, guanosine-5'-O-(2-thiodiphosphate), competitively inhibited this stimulation. Thermal inactivation studies distinguished putative guanine-nucleotide regulatory protein (N) from the catalytic unit (C) of yeast adenylate cyclase. Yeast N, which conferred guanine nucleotide regulation and the ability to utilize MgATP on yeast C, was quickly inactivated by incubation of particulate extracts at 30 degrees C. In contrast, yeast C, which apparently utilized MnATP as substrate in the absence of a functional N protein, resisted inactivation at 30 degrees C. These observations suggested that physically distinct protein components mediated the catalytic activity of yeast adenylate cyclase and its regulation by guanine nucleotides. These findings indicate a striking homology between the adenylate cyclase systems of S. cerevisiae and those of vertebrate cells.
Solubility of oxygen in electrolyte solutions (1978)

Knowledge of oxygen saturation solubilities is important for the design of waste water treatment and aerobic fermentations. Currently the oxygen polarographic probe is usually used to measure partial pressures of dissolved oxygen. For the determination of physical mass transfer coefficients in synthetic fermentation media, the oxygen saturation solubility need not be known if the underlying equations are linear; knowledge of the oxygen partial pressure will suffice. However, if the performance of a fermentor is to be determined, especially if oxygen is a
Steel Castings Handbook (1995)

Steel Castings Handbook, Sixth Edition contains information and engineering data relevant to the design, manufacture, and application of steel castings. The book's content is organized into five multiple-chapter sections, covering the design process, manufacturing equipment and procedures, purchasing, detailed application examples, and material selection for property optimization and manufacturability. The handbook also includes an appendix with composition and hardness data for a wide range of casting alloys and coverage on heat treatments, molding methods, redesign for casting, and the effect of quality on component performance. With its detailed explanations and extensive use of illustrations, the book serves equally well as a reference, text, or guide for both new and experienced engineers. For information on the print version, ISBN 978-0-87170-556-3, follow this link.
Multilayer Assemblies of Silica-Encapsulated Gold Nanoparticles on Decomposable Colloid Templates (2001)

Core–shell particles with tailored optical properties are obtained via manipulation of the number of Au@SiO2 nanoparticle layers deposited onto larger polymer spheres. The surface characteristics of silica, which surrounds the gold nanoparticles, are exploited to achieve a dense and uniform nanoparticle coating. The layer-by-layer (LbL) self-assembly technique yet again proves to be a worthy asset for the preparation of these novel metal-based core–shell and hollow colloids (see Figure).
Online Adaptive Code Generation and Tuning (2011)

In this paper, we present a runtime compilation and tuning framework for parallel programs. We extend our prior work on our auto-tuner, Active Harmony, for tunable parameters that require code generation (for example, different unroll factors). For such parameters, our auto-tuner generates and compiles new code on-the-fly. Effectively, we merge traditional feedback directed optimization and just-in-time compilation. We show that our system can leverage available parallelism in today's HPC platforms by evaluating different code-variants on different nodes simultaneously. We evaluate our system on two parallel applications and show that our system can improve runtime execution by up to 46% compared to the original version of the program.
Inflammation in Human Brain Injury: Intracerebral Concentrations of IL-1 <i>α</i> , IL-1 <i>β</i> , and Their Endogenous Inhibitor IL-1ra (2007)

Following traumatic brain injury (TBI), cascades of inflammatory processes occur. Laboratory studies implicate the cytokines interleukin-1alpha (IL-1alpha) and IL-1beta in the pathophysiology of TBI and cerebral ischemia, whilst exogenous and endogenous interleukin-1 receptor antagonist (IL-1ra) is neuroprotective. We analyzed IL-1alpha, IL-1beta, and IL-1ra in brain microdialysates (100-kDa membrane) in 15 TBI patients. We also analyzed energy-related molecules (glucose, lactate, pyruvate, glutamate, and the lactate/pyruvate ratio) in these brain microdialysates. Mean of mean (+/-SD) in vitro microdialysis percentage recoveries (extraction efficiencies) were IL-1alpha 19.7+/-7.6%, IL-1beta 23.9+/-10.5%, and IL-1ra 20.9+/-6.3%. In the patients' brain microdialysates, mean of mean cytokine concentrations (not corrected for percentage recovery) were IL-1alpha 5.6+/-14.8 pg/mL, IL-1beta 10.4+/-14.7 pg/mL, and IL-1ra 2796+/-2918 pg/mL. IL-1ra was consistently much higher than IL-1alpha and IL-1beta. There were no significant relationships between IL-1 family cytokines and energy-related molecules. There was a significant correlation between increasing IL-1beta and increasing IL-1ra (Spearman r=0.59, p=0.028). There was also a significant relationship between increasing IL-1ra and decreasing intracranial pressure (Spearman r=-0.57, p=0.041). High concentrations of IL-1ra, and also high IL-1ra/IL-1beta ratio, were associated with better outcome (Mann Whitney, p=0.018 and p=0.0201, respectively), within these 15 patients. It is unclear whether these IL-1ra concentrations are sufficient to antagonize the effects of IL-1beta in vivo. This study demonstrates feasibility of our microdialysis methodology in recovering IL-1 family cytokines for assessing their inter-relationships in the injured human brain, and suggests a neuroprotective role for IL-1ra. It remains to be seen whether exogenous IL-1ra or other agents can be used to manipulate cytokine levels in the brain, for potential therapeutic effect.
MEMBRANES OF ANIMAL CELLS (1968)

Turnover studies of the surface membrane and of cell particulate matter of L cells in tissue culture in logarithmic and plateau phase of growth have been made. The rate of incorporation of isotope into these fractions and the rate of fall of specific activities of labeled L-cell fractions have been observed. The following interpretation of the data appears most likely although other interpretations are possible. Growing and nongrowing cells synthesize approximately similar amounts of surface membrane and particulate material. In the growing cell the material is incorporated with net increases in substance. There is relatively little turnover. In the nongrowing cell newly synthesized material is incorporated, but a corresponding amount of material is eliminated so that there is turnover without net increase of substance. Our results suggest that there is no gross differential turnover between the protein, lipid, and carbohydrate of the surface membrane under the conditions of our experiments. Metabolic inhibitors or omission of amino acids in the culture medium lead to a decrease in synthesis of surface membrane and cell particulates and cause an equivalent decrease in the rate of degradation of surface membrane and of particulates; therefore the synthetic and degradative aspects of turnover appear to be coupled. As cultures of nongrowing cells in suspension or on a glass surface age, their synthetic and turnover capacities diminish. Our results suggest that the cell may exist in a nongrowing state with a level of synthesis similar to that of a growing cell. It can exist in this state with a high level of turnover.
Allelic variants of natriuretic peptide receptor genes are associated with family history of hypertension and cardiovascular phenotype (2003)

The novel Npr1 gene 3C variant and the Npr3 gene C(-55) allele are associated with hypertensive family history. Moreover, the functional Npr1 3C variant, when homozygous, is also associated with higher systolic blood pressure and prolonged ventricular relaxation.
The Role of Allogenic Fibroblasts in an Acute Wound Healing Model (2004)

Skin is the first tissue-engineered organ to have been successfully developed in the laboratory, and it has been clinically available for use as epidermal sheets for some time. As refinements in this field of tissue engineering continue, several key issues give cause for concern. One issue is the need to form a more complete dermal analogue before grafting. To this end, fibroblasts may be used in vitro to deposit extracellular matrix components within a basic scaffold, laying down those molecules not endogenous to the material and thereby improving the quality of the skin replacement. Many studies have shown the benefits of in vitro seeding with fibroblasts, but there has been some debate regarding the longevity of such cells after allotransplantation into an immunocompetent host. In this study, the authors set out to determine the longevity of transplanted cells in an immunocompetent porcine model. A total of 24 wounds were made on four female animals, 12 of which were covered with acellular hyaluronic acid dermal matrices, and the remainder of which were covered with matrices seeded with allogenic (male) fibroblasts. After a week in vivo, the wounds were grafted with either split-thickness skin grafts or cultured epithelial autograft. Biopsy specimens were obtained from wounds at varying time intervals and assessed using genetic analysis to determine the survival of allotransplanted cells. No cells were detectable by polymerase chain reaction analysis (sensitivity, 1:100,000) after 7 days in vivo. Subsequent histologic examination demonstrated little difference in wound morphology. The authors conclude that allogenic fibroblasts do not survive transplantation in a porcine wound model.