gebhart/patrepeval huggingface dataset:
A Hybrid Approach of Secret Sharing with Fragmentation and Encryption in Cloud Environment for Securing Outsourced Medical Database: A Revolutionary Approach (2018)

Cloud Computing is observed as the greatest paradigm change in Information technology. Data outsourcing is an inventive representation with the intention of trustworthy storage and proficient query execution to customers. Data stored on the cloud is showing great attention. However, the security issues allied with data storage over the cloud is a chief daunting cause for potential adopters. Hence the focus is to find techniques that will offer more security. Many diseases fighting organizations are working together io implement cloud as a data sharing vehicle. It is obligatory to build up innovative solutions with the intention of amalgamate diverse approaches in order to generate flexible and adaptable systems, particularly for achieving elevated levels of utilization of developed algorithms. In this document, we suggest an innovative model based on fragmentation, secret sharing and encryption for medical databases which will divide the data amongst several cloud service providers. We develop a systematic structure exploiting the sensitive nature of information and results in enhanced security level. A database for medical system is represented as Entity association and Relational model. A cloud based model is proposed to offer secure patient centric right to access PHR in a competent way. The simulation results implemented in NetBeans Java for performance evaluation of existing cryptographic techniques are shown. Our security model is evaluated using CrypTool 1.4.30 considering the entropy of algorithms. The future work includes development of a computerized system retrieving, storing and maintaining data efficiently and quickly.
The Central Melanocortin System and Fever (2003)

Fever is a phylogenetically ancient response that is mounted upon exposure of the host to pathogens or inflammatory agents. Melanocortin agonists act centrally to inhibit fever by acting at receptors, including the melanocortin-4 receptor, which is prominently expressed in key hypothalamic thermoregulatory centers. Furthermore, endogenous melanocortins act centrally as physiological modulators of fever, recruited during the febrile response to restrain its intensity. Functionally, these actions lie at the interface between the anti-inflammatory effects of melanocortins, which involve suppression of the synthesis and actions of proinflammatory cytokines, and the central control of thermoregulation. Considering the extensive neuroanatomic and functional overlaps between central pathways and peripheral effectors involved in thermoregulation and energy balance, it is not surprising that melanocortins have been found to influence the metabolic economy profoundly in pathological as well as normal states. For example, despite suppressing endotoxin-induced fever, endogenous melanocortins appear to mediate the associated anorexia, a classic component of the "illness syndrome" accompanying acute infections, and promote a negative energy balance. The thermoregulatory actions of melanocortins are in several respects functionally opposed, and are remarkably dependent on physiological state, indicating that responsiveness to melanocortins is a physiologically modulated variable. Elucidating the anti-inflammatory and thermoregulatory roles of central melanocortin receptors during inflammatory states may lead to novel pharmacotherapeutic targets based on selective targeting of melanocortin receptor subtypes, for clinical benefit in human disease states involving neuroinflammatory components and metabolic wasting.
Second-harmonic generation to 2048 Å in Β-Ba&lt;inf&gt;2&lt;/inf&gt;O&lt;inf&gt;4&lt;/inf&gt; (1986)

<tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">\Beta</tex> -BaB <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> has been found to be phase matchable for second-harmonic generation down to 2048 Å at room temperature. Sellmeier's equations, which are highly accurate from 1.064 μm to 2050 Å, are reported.
Particulate Contamination and Microelectronics Manufacturing: An Introduction (1986)

The manufacture of integrated circuits for computers and various microprocessors is of increasing importance. Higher speeds of operation and lower costs require higher circuit densities, thus further miniaturization. Circuit elements have features in the submicron size domain and are quite sensitive to contaminant particles of comparable sizes. People, equipment, chemicals, and piping generate particles which are transported to the vicinity of the product and some of which are deposited. The deposition rate depends upon the airborne particle size distribution and the concentration and the deposition velocities caused by various deposition mechanisms. Methods for measuring submicron particles in gases and on surfaces are widely used and are being further developed, along with improved methods for data analysis. Cleaning submicron particles from surfaces is difficult; those particles that remain can have major impacts on process yield, to which process economic viability is strongly related. Research is needed in: source determination, transport modeling, aerosol characterization, deposition mechanisms, surface particle characterization, cleaning, defect analysis, and the design of processes and products that are robust.
Cutting Edge: Functional Requirement for SAP in 2B4-Mediated Activation of Human Natural Killer Cells as Revealed by the X-Linked Lymphoproliferative Syndrome (2000)

X-linked lymphoproliferative syndrome (XLP) is an immunodeficiency characterized by life-threatening infectious mononucleosis and EBV-induced B cell lymphoma. The gene mutated in XLP encodes SLAM (signaling lymphocytic activation molecule-associated protein)-associated protein (SAP), a small SH2 domain-containing protein. SAP associates with 2B4 and SLAM, activating receptors expressed by NK and T cells, and prevents recruitment of SH2 domain-containing protein tyrosine phosphatase-2 SHP-2) to the cytoplasmic domains of these receptors. The phenotype of XLP may therefore result from perturbed signaling through SAP-associating receptors. We have addressed the functional consequence of SAP deficiency on 2B4-mediated NK cell activation. Ligating 2B4 on normal human NK cells with anti-2B4 mAb or interaction with transfectants bearing the 2B4 ligand CD48 induced NK cell cytotoxicity. In contrast, ligation of 2B4 on NK cells from a SAP-deficient XLP patient failed to initiate cytotoxicity. Despite this, CD2 or CD16-induced cytotoxicity of SAP-deficient NK cells was similar to that of normal NK cells. Thus, selective impairment of 2B4-mediated NK cell activation may contribute to the immunopathology of XLP.
Mesophase Mechanisms in the Formation of the Microstructure of Petroleum Coke (1976)

Carbon and graphite materials are required to withstand increasingly severe conditions of thermal shock, stress, and reactor irradiation in the steelmaking, aluminum, aerospace, and nuclear industries. The performance of these materials depends to a large degree on the characteristics of the filler coke, which is conventionally produced by the delayed coking of various heavy refinery feedstocks. Thus more stringent demands are being made on the quality of petroleum coke at the same time as the supply patterns for the coking feedstocks are changing rapidly. This situation has motivated the investigations summarized here, which seek an understanding of how micro structure s form in order to assist in producing more homogeneous cokes of improved quality. Studies of the carbonization of coal and petroleum precursors, as well as various model organic compounds, have confirmed and added much detail to the point first made by Brooks and Taylor (1, 2), viz., that the
Highly pH and Temperature Responsive Microgels Functionalized with Vinylacetic Acid (2004)

Temperature-responsive microgels based on poly(N-isopropylacrylamide) (PNIPAM) and functionalized with vinylacetic acid (VAA) are observed to exhibit a host of novel swelling responses compared with equally functionalized microgels prepared using the conventional acrylic acid (AA) and methacrylic acid (MAA) comonomers. VAA−NIPAM microgels are ionized over a narrow pH range and show functional group pKa values which are independent of the degree of ionization. Ionization induces a much larger swelling response in VAA−NIPAM microgels than in the conventional microgels; upon ionization at physiological temperature, VAA−NIPAM swells 3 times more than either AA−NIPAM or MAA−NIPAM. VAA−NIPAM microgels also display sharp, PNIPAM-like thermal deswelling profiles when protonated but, upon ionization, undergo no volume phase transition up to at least 70 °C. The highly responsive and tunable ionization and swelling profiles observed for VAA−NIPAM are consistent with the tendency of VAA to behave as a chain transfer agent, resulting in the incorporation of a large number of well-separated VAA units on highly mobile chain ends at or near the microgel surface. VAA−NIPAM microgels may thus be ideal for use in biomolecule separation, medical diagnostics, and biodelivery applications in which sharp responses to multiple environmental stimuli are required.
Detection and differentiation of antigenically distinct small round-structured viruses (Norwalk-like viruses) by reverse transcription-PCR and southern hybridization (1995)

Application of reverse transcription (RT)-PCR to detect small round-structured viruses (SRSVs) from fecal specimens of patients with gastroenteritis has been insensitive because of the tremendous sequence heterogeneity between strains. We have designed two RT-PCR primer sets (G-1 and G-2) based on the nucleotide sequence diversity in the RNA polymerase gene of SRSVs belonging to two distinct genogroups represented by Norwalk virus (primers G-1) and Snow Mountain agent (primers G-2). All 22 SRSV strains examined that had been classified previously by solid-phase immune electron microscopy into four antigenic types (UK1, UK2, UK3, and UK4) could be detected by RT-PCR with these two primer sets. The G-1 primer set detected 6 UK2 strains, and the G-2 primers detected 16 strains, including 7 UK1, 5 UK3, and 4 UK4 strains. On the basis of nucleotide sequences of 81-bp fragments of the RT-PCR products from 13 strains determined in this study, together with those previously reported for 17 SRSV strains, we designed four sets of internal oligonucleotide probes (P1-A, P1-B, P2-A, and P2-B) for Southern hybridization, using chemiluminescent detection. The P1-A probe hybridized with PCR products from the UK2 strains; the P1-B probe, with products from two of the seven UK1 strains; the P2-A probe, with four of the remaining five UK1 strains; and the P2-B probe, with products from both UK3 and UK4 strains, as well as with one strain originally typed as UK1 which showed cross-reactivity with UK4 upon retesting by solid-phase immune electron microscopy. RT-PCR with both the G-1 and the G-2 primer sets can increase the detection rate of the many antigenically distinct SRSVs and, when combined with Southern hybridization, may predict the antigenic type of the SRSV associated with infection.
Statistical Forecasting of Electric Power Restoration Times in Hurricanes and Ice Storms (2007)

This paper introduces a new method for estimating the time at which electric power will be restored after a major storm. The method was applied for hurricanes and ice storms for three major electric power companies on the East Coast. Using an unusually large dataset that includes the companies' experiences in six hurricanes and eight ice storms, accelerated failure time models were fitted and used to predict the duration of each probable outage in a storm. By aggregating those estimated outage durations and accounting for variable outage start times, restoration curves were then estimated for each county in the companies' service areas. The method can be applied as a storm approaches, before damage assessments are available from the field, thus helping to better inform customers and the public of expected post-storm power restoration times. Results of model applications using testing data suggest they have promising predictive ability.
Magnification factors for the SOM and GTM algorithms (1997)

Magnification factors specify the extent to which the area of a small patch of the latent (or `feature') space of a topographic mapping is magnified on projection to the data space, and are of considerable interest in both neuro-biological and data analysis contexts. Previous attempts to consider magnification factors for the self-organizing map (SOM) algorithm have been hindered because the mapping is only defined at discrete points (given by the reference vectors). In this paper we consider the batch version of SOM, for which a continuous mapping can be defined, as well as the Generative Topographic Mapping (GTM) algorithm of Bishop et al. (1997) which has been introduced as a probabilistic formulation of the SOM. We show how the techniques of differential geometry can be used to determine magnification factors as continuous functions of the latent space coordinates. The results are illustrated here using a problem involving the identification of crab species from morphological data.
Experimental Study of Random Wave Impact On a Horizontal Plate (2010)

This paper presents the results of experimental research on random wave impact on a horizontal plate. The test wave is unidirectional and irregular wave. The experiments are carried out with perpendicular random waves (β = 0°) and oblique random waves (β= 15°, 30°, 45°), the significant wave heights H1/3 ranging from 7.5 to 20 cm with 2.5 cm increment, the peak wave periods Tp ranging from 1.0 to 2.0 s with 0.2 s increment, and the clearance of the model with respect to the significant wave height s/H1/3 ranging from 0.0 to 0.5 with 0.1 increment. Wave impact pressures are obtained by using wavelet analysis to remove noise signals from the dynamic responses of the instruments. The distribution characteristic is given for the impact pressures of the perpendicular and oblique waves along the underside of the plate. The influence of different incident wave parameters including the relative water height H1/3/d, the relative plate width B/L and the relative clearance s/H1/3 on the non-dimensional wave impact forces is discussed.
Assessment of Extrastriatal Vesicular Monoamine Transporter Binding Site Density Using Stereoisomers of [<sup>11</sup>C]Dihydrotetrabenazine (1999)

Previous studies have demonstrated the utility of [11C]dihydrotetrabenazine ([11C]DTBZ) as a ligand for in vivo imaging of the vesicular monoamine transporter system. The (+)-isomer has a high affinity (approximately 1 nmol/L) for the vesicular monoamine transporter (VMAT2) binding site, whereas the (-)-isomer has an extremely low affinity (approximately 2 micromol/L). Efforts to model dynamic (+)-[11C]DTBZ data demonstrate the difficulty in separating the specific binding component from the free plus nonspecific component of the total positron emission tomography (PET) measure. The authors' previous PET work, as well as in vitro studies, indicate that there is little specific VMAT2 binding in neocortical regions. However, precise determination of in vivo binding levels have not been made, leaving important questions unanswered. At one extreme, is there sufficient specific binding in cortex or other extrastriate regions to be estimated reliably with PET? At the other extreme, is there sufficiently little binding in cortex so that it can be used as a reference region representing nonsaturable tracer uptake? The authors address these questions using paired studies with both active (+) and inactive (-) stereoisomers of [11C]DTBZ. Six normal control subjects were scanned twice, 2 hours apart, after injections of 16 mCi of (+)- and (-)-[11C]DTBZ (order counter-balanced). Three-dimensional PET acquisition consisted of 15 frames over 60 minutes for each scan. Arterial samples were acquired throughout, plasma counted, and corrected for radiolabeled metabolites. Analysis of specific binding was assessed by comparison of total distribution volume measures from the (+)- and (-)-[11C]DTBZ scans. The authors' findings indicate that only approximately 5% of the cortical signal in (+)-[11C]DTBZ scans results from binding to VMAT2 sites. The strongest extrastriatal signal comes from the midbrain regions where approximately 30% of the PET measure results from specific binding. The authors conclude that (1) the density of VMAT2 binding sites in cortical regions is not high enough to be quantified reliably with DTBZ PET, and (2) binding does appear to be low enough so that cortex can be used as a free plus nonspecific reference region for striatum.
Prognostic value of high serum levels of CA‐125 in malignant secretory peritoneal mesotheliomas affecting young women. A case report with differential diagnosis and review of the literature (1997)

Besides its clinicopathological characteristics and its histological, immunohistochemical and ultrastructural features, we describe its biological behaviour, which seems to be worst when CA-125 levels are high.
Real-time American Sign Language Recognition using wrist-worn motion and surface EMG sensors (2015)

A Sign Language Recognition (SLR) system enables communication between hearing disabled individuals and those who can hear and speak. With the prevalence of the wearable computers, this technology is becoming an important human computer interface capable of reading hand gestures and inferring user;s intent. In this paper, we propose a real-time American SLR system leveraging fusion of surface electromyography (sEMG) and a wrist-worn inertial sensor at the feature level. A feature selection is provided for 40 most commonly used words and for four subjects. The experimental results show that after feature selection and conditioning, our system achieves 95.94% recognition rate. The results also illustrate the fusion of two modalities perform better than using only the inertial sensor. We observed that only one channel of sEMG (out of four) located on the wrist and under the wrist-watch is sufficient.
Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes (2007)

We identified 120 multiple myeloma (MM) cases with satisfactory cytogenetic evaluation and abnormal karyotypes. Hyperdiploid karyotype was found in 77 cases (64%), hypodiploid in 30 cases (25%), and the remaining 13 cases (11%) had a pseudodiploid karyotype. The most common numerical abnormalities were gains of chromosomes 15, 9, 3 followed by chromosomes 19, 11, 7, 21, and 5. Whole chromosome losses were also frequent involving primarily chromosomes X/Y, 8, 13, 14, and 22. Most cases showed also structural rearrangements leading to del(1p), dup(1q), del(5q), del(6q), del(8p), del(9p), del(13q), and del(17p). Chromosome 13/13q deletion was found in 52% of cases; complete loss of 13 was observed in 73% of cases, whereas 27% had interstitial deletions. In addition, 13/13q deletions occurred in 75% of nonhyperdiploid myeloma but only 39% of the hyperdiploid had 13/13q deletions. Translocations affecting 14q32/IGH region was seen 40 cases; t(11;14)(q13;q32) in 17 cases, t(14;16)(q32;q23) and t(8;14)(q24;q32) in three cases each, and t(6;14)(p21;q32) and t(1;14)(q21;q32) in two cases each. The remaining 14q32 translocations had various t(V;14) partners or of an undetermined origin. Remarkably, the 14q32/IGH translocations were less frequent in the hyperdiploid karyotypes than the nonhyperdiploid karyotypes (17 vs. 63%). Fourteen cases showed break at 8q24/CMYC site; seven of those had Burkitt's-type translocations. Our results revealed that conventional cytogenetics remains an important tool in elucidating the complex and divers genetic anomalies of MM. Cytogenetics identifies two distinct groups of MM, hyperdiploid and nonhyperdiploid, and establishes the presence of prognostic chromosomal markers such as 13/13q, 17p, 8q24, and 16q aberrations.
Noncontact Miniature Torque Sensor for Automotive Application (1982)

<div class="htmlview paragraph">A noncontact torque sensor has been developed for use in engine control systems. The sensor detects torque-induced changes in magnetic properties of the engine crankshaft.</div> <div class="htmlview paragraph">A miniature version of the sensor, mounted on a 1980 Chevrolet V-6 engine, is described. Sensor installation requires 22 mm of crankshaft space and a 1.0 mm air gap between sensor and crankshaft is utilized. For a variation of engine torque from −100 to 240 N·m, the sensor generates a linear signal which varies from −25 to 60 mV; amplification is used to provide an output signal of −500 to 1200 mV. A signal processor associated with the sensor is calibrated to give a torque sensitivity of 5 mV/N·m and it also includes an active filter with a low-pass cutoff frequency of 5 Hz.</div> <div class="htmlview paragraph">In its present state of development, torque measurement accuracy of the sensor is limited to approximately ±10 percent due to interfering effects of temperature, air gap variation, and engine speed sensitivity. Further investigation will be necessary to establish the ultimate performance potential of the sensor.</div>
Purification and some properties of glutathione S-transferase from Escherichia coli B (1989)

Glutathione S-transferase was purified approximately 2,300-fold from cell extracts of Escherichia coli B with a 7.5% activity yield. The molecular weight of the enzyme was 45,000, and the enzyme appeared to consist of two homogeneous subunits. The enzyme was almost specific to 1-chloro-2,4-dinitrobenzene (Km, 1.43 mM) and glutathione (Km, 0.33 mM). The optimal pH and optimal temperature for activity were 7.0 and 50 degrees C, respectively, and the enzyme was stable from pH 5 to 11. The activity of the enzyme for 1-chloro-2,4-dinitrobenzene (3,2 mumol/min per mg of protein) was significantly lower than those of the enzymes from mammals, plants, and fungi.
13. Experiments on the synthesis of substances related to the sterols. Part XIV. A simple synthesis of certain octalones and ketotetrahydrohydrindenes which may be of angle-methyl-substituted type. A theory of the biogenesis of the sterols (1937)

E. C. du Feu, F. J. McQuillin and R. Robinson, J. Chem. Soc., 1937, 53 DOI: 10.1039/JR9370000053