gebhart/patrepeval huggingface dataset:
Reaction of Fructose with Benzylamine (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of Fructose with BenzylamineJohn F. CarsonCite this: J. Am. Chem. Soc. 1956, 78, 15, 3728–3731Publication Date (Print):August 1, 1956Publication History Published online1 May 2002Published inissue 1 August 1956https://pubs.acs.org/doi/10.1021/ja01596a049https://doi.org/10.1021/ja01596a049research-articleACS PublicationsRequest reuse permissionsArticle Views332Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Ageing of human epidermis: the role of apoptosis, Fas and telomerase (2004)

Fas/FasL-mediated apoptosis, along with decreased proliferation, may have a role in changes of human epidermis during ageing. Telomerase activity did not appear to be limiting in young vs. old human epidermis.
Study of epoxy/CNT nanocomposites prepared via dispersion in the hardener (2011)

In this study, carboxylated (SWCNT-c) and pristine (SWCNT) single-walled carbon nanotubes were randomly dispersed in a hardener prior to mixing it with an epoxy resin. The influence of several parameters on the dispersion process were investigated. The produced samples were characterized by infrared spectroscopy, differential scanning calorimetry, dilatometry, dynamic mechanical analysis, scanning electron microscopy and mechanical testing (tensile, flexural and microhardness). The results obtained with the nanocomposites with SWCNT-c suggested that the lowest time and amplitude of sonication improved the mechanical properties. The use of a solvent (acetone) was important to improve dispersion, ultimately increasing microhardness and Young's Modulus up to 32%. Nanocomposites with 0.25 wt. (%) SWCNT-c presented superior mechanical properties compared to those with 0.50 wt. (%) SWCNT. Two simple mathematical models (rule of mixtures and Halpin-Tsai) were used to predict Young's Modulus of the composites yielding results very close to the experimental ones.
Unconventional methods and unconventional materials for microfabrication (2002)

This talk will outline the rapid progress in soft lithography-microcontact printing, micromolding in capillaries, and transfer molding of organic polymers. These new techniques cover only a part of the range of problems in the fabrication, testing and production of microelectronic systems, but they have an immediate, broad application in a number of other areas requiring small systems from homogeneous self-assembled monolayers (SAMs) to transistors, and from molecular self-assembly to the self-assembly of macro-scale objects.
GaAlAs Schottky directional-coupler switch (1977)

Electro-optic metal-gap directional-coupler switches have been fabricated in GaAlAs waveguide structures. A very thin GaAs cap facilitates the electroplating of Schottky barriers without significantly increasing the optical attenuation at wavelengths near 8600 Å, making this type of device suitable for integration with a GaAs laser source on a common chip. The performance of the switch was investigated at 1.06 m. A 17-dB extinction ratio in the coupled channel was measured at a reverse-bias voltage of 25 V.
Cobalt(II)-Catalyzed Reaction of Enolizable Aldehydes with Alkenes in the Presence of Dioxygen: The Role of Acyl Radical (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCobalt(II)-Catalyzed Reaction of Enolizable Aldehydes with Alkenes in the Presence of Dioxygen: The Role of Acyl RadicalT. Punniyamurthy, Beena Bhatia, and Javed IqbalCite this: J. Org. Chem. 1994, 59, 4, 850–853Publication Date (Print):February 1, 1994Publication History Published online1 May 2002Published inissue 1 February 1994https://pubs.acs.org/doi/10.1021/jo00083a029https://doi.org/10.1021/jo00083a029research-articleACS PublicationsRequest reuse permissionsArticle Views799Altmetric-Citations62LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Predicting drug side-effect profiles: a chemical fragment-based approach (2011)

Abstract Background Drug side-effects, or adverse drug reactions, have become a major public health concern. It is one of the main causes of failure in the process of drug development, and of drug withdrawal once they have reached the market. Therefore, in silico prediction of potential side-effects early in the drug discovery process, before reaching the clinical stages, is of great interest to improve this long and expensive process and to provide new efficient and safe therapies for patients. Results In the present work, we propose a new method to predict potential side-effects of drug candidate molecules based on their chemical structures, applicable on large molecular databanks. A unique feature of the proposed method is its ability to extract correlated sets of chemical substructures (or chemical fragments) and side-effects. This is made possible using sparse canonical correlation analysis (SCCA). In the results, we show the usefulness of the proposed method by predicting 1385 side-effects in the SIDER database from the chemical structures of 888 approved drugs. These predictions are performed with simultaneous extraction of correlated ensembles formed by a set of chemical substructures shared by drugs that are likely to have a set of side-effects. We also conduct a comprehensive side-effect prediction for many uncharacterized drug molecules stored in DrugBank, and were able to confirm interesting predictions using independent source of information. Conclusions The proposed method is expected to be useful in various stages of the drug development process.
Photolytic cleavage of DNA by nitrobenzamido ligands linked to 9-aminoacridines gives DNA polymerase substrates in a wavelength-dependent reaction (1991)

A series of reagents containing 3- or 4-nitrobenzamido ligands tethered to 9-aminoacridine via variable-length linkers have been prepared and their properties as photochemical DNA cleavers (photonucleases) examined. When irradiated with approximately 300-nm light, where the nitrobenzamido ligand can absorb, they cleave DNA in an oxygen-independent reaction presumably involving oxygen transfer from the nitro group to the deoxyribose units of the DNA backbone (Nielsen et al., 1988b). This reaction is pH independent and only slightly affected by the linker length, and the DNA fragments are not substrates for DNA polymerase. When approximately 420-nm light is used, were only the 9-aminoacridinyl ligands absorb, the DNA cleavage is also oxygen-independent but pH dependent, requires DNA saturation with the reagent (base pair:reagent less than or equal to 2), and is most efficient with the longer linkers. The cleavage is specific for guanine residues and results in 5'-phosphate termini and heterogeneous (more than four products) 3'-termini. One of the products is presumably 3'-hydroxy since DNA photocleaved with nitrobenzamido acridine reagents and 420-nm radiation are substrates for DNA polymerase in a nick translation assay as well as for the Klenow fragment. An electron-transfer mechanism is suggested.
A multi-specialist architecture for sensor fusion in remote sensing (2003)

Presents a scene interpretation architecture in the context of multi-sensor fusion. This architecture is based on blackboard and multi-specialist concepts, and offers knowledge representation capabilities to express knowledge about an application in an explicit way. Knowledge description includes the characteristics of the sensors, and a semantic object description independent of the sensor characteristics. The detection strategy is based on the fundamental notion of spatial context linking the objects of the scene, and the notion of salient object. An interpretation is a semantic model of the real observed scene, including object location, object characteristics and relations between objects. This architecture has a highly modular structure allowing easy incorporation of new knowledge, and new specialists. To demonstrate the reliability of the approach, an application of SAR/SPOT data fusion developed with this architecture is briefly presented, and the results of an interpretation session are shown.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Foreword (1985)

Research Article| August 01, 1985 Foreword Robert T. Bean Robert T. Bean 2729 Willowhaven Dr., La Crescenta, CA 91214 Search for other works by this author on: GSW Google Scholar Author and Article Information Robert T. Bean 2729 Willowhaven Dr., La Crescenta, CA 91214 Publisher: Association of Environmental & Engineering Geologists First Online: 09 Mar 2017 Online Issn: 1558-9161 Print Issn: 1078-7275 © 1985 Association of Engineering Geologists Environmental & Engineering Geoscience (1985) xxii (3): 229. https://doi.org/10.2113/gseegeosci.xxii.3.229 Article history First Online: 09 Mar 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation Robert T. Bean; Foreword. Environmental & Engineering Geoscience 1985;; xxii (3): 229. doi: https://doi.org/10.2113/gseegeosci.xxii.3.229 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyEnvironmental & Engineering Geoscience Search Advanced Search This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Practical Handbook of Ground-Water Monitoring (1991)

Regulatory Mandates for Controls on Ground Water Monitoring. Ground Water Monitoring System Design. The Overall Philosophy and Purpose of Site Investigations. Remote Sensing and Geophysical Methods for Evaluation of Subsurface Conditions. Monitoring and Sampling in the Vadose Zone. Monitoring Well Drilling, Soil Sampling, Rock Coring and Borehole Logging. Design and Installation of Ground Water Monitoring Wells. Monitoring Well Post-Installation Considerations. Acquisition and Interpretation of Water Level Data. Methods and Procedures for Defining Aquifer Parameters. Ground Water Sampling. Ground Water Sample Analysis. Organization and Analysis of Water Quality Data. Health and Safety Consideration in Ground Water Monitoring Investigations. Decontamination Program Design for Ground Water Investigations.
Organocatalytic Direct Vinylogous Michael Addition of α,β‐Unsaturated γ‐Butyrolactam to α,β‐Unsaturated Aldehydes and an Illustration to Scaffold Diversity Synthesis (2010)

Ideal for scaffold diversity synthesis: The first organocatalytic direct vinylogous Michael addition of N-Boc α,β-unsaturated γ-butyrolactam to α,β-unsaturated aldehydes has been developed. The products with multiple orthogonal sets of functionalities were transformed into diverse enantioenriched natural-product-like or drug-like molecules with fused bi-, tri-, or polycyclic scaffolds (see scheme), which might have potential for biologically related studies. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
On-chip cache memory resilience (2002)

This paper investigates the system-level impact of soft errors occurring in cache memory and proposes a novel cache-memory design approach for improving the soft-error resilience. Radiation experiments are conducted to quantify the severity of errors attributed to transients occurring in a cache memory subsystem. Simulation-based fault injections are then conducted to determine major failure modes and to assess the cost/benefits in cache memory designs/configuration alternatives. The performance, reliability, and overhead for each design configuration, e.g., cache block-size and write policy, are studied. The results indicate that the performance enhancement approaches using large cache block-sizes can adversely affect the soft-error sensitivity of the system. Write-through cache design is more susceptible to incomplete/incorrect program termination, while write-back cache design is more prone to data corruptions. A resilient cache design scheme, selective set invalidation (SSI), that better scrubs the cache-memory errors is proposed and evaluated.
FIEL INTERPRETACION DE LOS AUTORES CLASICOS GRECOLATINOS Y LATINOAMERICANOS (1977)

EL DOCTOR GERMAN VIVEROS MALDONADO, DIRECTOR DEL CENTRO DE ESTUDIOS CLASICOS, EN ENTREVISTA HABLA DE LA HISTORIA DE DICHO CENTRO; DE SU CREACION, FUNCIONES Y OBJETIVOS, ENTRE LOS QUE DESTACAN: INVESTIGAR Y DIFUNDIR LA CULTURA CLASICA GRECOLATINA; DAR A CONOCER E INVESTIGAR LOS FONDOS DOCUMENTALES LATINOAMEXICANOS, Y PROPORCIONAR INSTRUMENTOS PARA LA ENSENANZA DE LAS LENGUAS Y LITERATURAS CLASICAS GRIEGAS Y LATINAS. SU IMPORTANCIA FUNDAMENTAL RESIDE EN LA INFLUENCIA QUE TIENEN LAS OBRAS DE LOS AUTORES CLASICOS GRECOLATINOS. LA MAESTRA LOURDES ROJAS, SECRETARIA ACADEMICA DEL CENTRO, PRESENTE DURANTE LA ENTREVISTA AL DOCTOR VIVEROS, EXPRESO QUE SE PRETENDE LOGRAR UNA INTEGRACION MULTIDISCIPLINARIA CON ESTUDIANTES, PROFESORES E INVESTIGADORES DE FACULTADES COMO LA DE FILOSOFIA Y LETRAS, DERECHO Y CIENCIAS POLITICAS Y SOCIALES, POR MEDIO DE LA CUAL SE PODRIAN LLEVAR A CABO TRABAJOS DE TRADUCCION DE AUTORES CLASICOS SIN TERGIVERSAR LAS IDEAS.
Electron Cyclotron Resonance Ion Source for Ion Thruster (1996)

An electron cyclotron resonance (ECR) ion source was designed and its performance was studied in comparison with a DC ion source. Ion production cost of 340 V/ion for ECR ion source and 189 V/ion for DC ion source were obtained at the pressure of 0.5 mTorr and the discharge power of 50 W. A luminosity distribution of the Ar-II line was imaged through an interferometer filter and a luminous arch hill was observed near the ECR region, where the plasma was resonantly generated. Ion wall loss measurement showed that the ion production cost became worse due to the excessive ion wall loss near the cusped magnets, where the plasma confinement was inferior to that of the DC ion source.
Acetal hydrolysis: the A1 mechanism (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcetal hydrolysis: the A1 mechanismSteven R. Wann and Maurice M. KreevoyCite this: J. Org. Chem. 1981, 46, 2, 419–423Publication Date (Print):January 1, 1981Publication History Published online1 May 2002Published inissue 1 January 1981https://pubs.acs.org/doi/10.1021/jo00315a037https://doi.org/10.1021/jo00315a037research-articleACS PublicationsRequest reuse permissionsArticle Views644Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Generalized Reverse Block Jacket Transform (2008)

Jacket matrices motivated by the center weight Hadamard matrices have played important roles in signal processing, communication, image compression, cryptography, etc. In this paper we propose a notation called block Jacket matrix which substitutes elements of the matrix into common matrices or even block matrices. Employing the well-known Pauli matrices which are very important in many subjects, block Jacket matrices with any size are investigated in detail, and some recursive relations for fast construction of the block Jacket matrices are obtained. Based on the general recursive relations, several special block Jacket matrices are constructed. To decompose high order block Jacket matrices, a fast decomposition algorithm for the factorable block Jacket matrices is suggested. After that some properties of the block Jacket matrices are investigated. Finally, several remarks are presented. These remarks are associated with comparisons between the Clifford algebra and the block Jacket matrices, generations of orthogonal and quasi-orthogonal sequences, and relations of the block Jacket matrices to the orthogonal transforms for signal processing. Since the Pauli matrices are actually infinitesimal generators of <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SU</i> (2) group, the proposed construction and decomposition algorithms for the block Jacket matrices are available in the signal processing, communication, quantum signal processing and information theory.
Synergistic Use of Talc in Halogen-Free Flame Retarded Polycarbonate/Acrylonitrile-Butadiene-Styrene Blends (2012)

Pyrolysis, flammability, fire behavior, melt viscosity, and gas diffusion of bisphenol A polycarbonate/acrylonitrile-butadiene-styrene (PC/ABS) were investigated, with bisphenol A bis(diphenyl phosphate) (BDP), with 10 wt.% talc and with BDP in combination with 5, 10 and 20 wt.% talc, respectively. Compared to PC/ABS, PC/ABS + BDP results in an increased decomposition temperature of PC, a higher char yield, a significantly increased LOI, a V-0 classification in UL 94, a reduced peak heat release rate (pHRR), and a reduced total heat release (THR) in the cone calorimeter. This efficient flame retardancy is due to mechanisms in both the gas and condensed phases. PC/ABS + 10 wt.% talc shows a decrease in the PC decomposition temperature. The fire behavior is improved in part compared to PC/ABS, with an increased LOI and reduced pHRR. PC/ABS + BDP + 10 wt.% talc shows a strong synergism in LOI, a V-0 classification, and a decrease in pHRR, whereas THR is slightly increased compared to PC/ABS + BDP. Talc decreases the gas diffusion and enhances the flow limit for low shear rates, both of which influence the pyrolysis and flammability results. Further, talc improves the protection properties of the fire residues. Nevertheless it also partly suppresses flame inhibition and the charring effect of BDP. The synergism between BDP and talc in LOI is obtained even for low talc loadings in PC/ABS + BDP + talc, whereas for higher loadings saturation is observed.
A 0.5 V PWM CMOS Imager With 82 dB Dynamic Range and 0.055% Fixed-Pattern-Noise (2013)

This paper presents a 0.5 V operated pulse-width modulation (PWM) CMOS imager with threshold-variation canceling (TVC) and programmable current-controlled threshold (PCCT) schemes implemented in 0.18 μm CMOS technology. The proposed TVC scheme efficiently improves the fixed-pattern-noise (FPN) issue caused by process variation in conventional PWM sensors. The limited dynamic range in ultra-low-voltage operated sensor can be extended by 56.5 dB with the proposed PCCT operation. The measurement results of the prototype chip show an array FPN of 0.055%, a column FPN of 0.016%, a dark random noise of 0.65 LSB, and a dynamic range (DR)of 82 dB. The total chip consumes 4.95 uW and 29.6 μW at 11.8 fps and 78.5 fps, which achieves an iFOM of 163.9 pW/f-p and 147.3 pW/f-p, respectively.
Piperidine Derivatives. XX. The Preparation and Reactions of 1-Methyl-3-piperidone (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPiperidine Derivatives. XX. The Preparation and Reactions of 1-Methyl-3-piperidoneS. M. McElvain and John F. VozzaCite this: J. Am. Chem. Soc. 1949, 71, 3, 896–900Publication Date (Print):March 1, 1949Publication History Published online1 May 2002Published inissue 1 March 1949https://doi.org/10.1021/ja01171a037RIGHTS & PERMISSIONSArticle Views919Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (659 KB) Get e-Alerts Get e-Alerts