gebhart/patrepeval huggingface dataset:
Performance analysis of signed correlation algorithm with recursive estimation of signed data covariance for fast convergent and robust adaptive filters (2011)

This paper derives a new adaptation algorithm named signed correlation algorithm with recursive estimation of signed data covariance (SCA-RESDC) that combines signed correlation algorithm (SCA) for complex-domain adaptive filters with recursive estimation of signed data covariance matrix of a strongly correlated filter reference input process. The SCA-RESDC achieves significant improvement in filter convergence speed of the SCA, while it preserves robustness of the latter algorithm against two types of impulse noise intruding adaptive filtering systems: one in observation noise and another at filter input. Analysis of the SCA-RESDC under Long Filter Assumption is fully developed for theoretically calculating filter convergence. Through experiment with simulations and theoretical calculations of filter convergence for the SCA-RESDC, we demonstrate its effectiveness in making adaptive filters fast convergent and robust in the presence of both types of impulse noise. Good agreement between simulated and theoretical convergence shows the validity of the analysis.
Selected Concepts and Investigations in Compound Classification, Molecular Descriptor Analysis, and Virtual Screening (2001)

ADVERTISEMENT RETURN TO ISSUEArticleNEXTSelected Concepts and Investigations in Compound Classification, Molecular Descriptor Analysis, and Virtual ScreeningJürgen BajorathView Author Information New Chemical Entities, Inc., 18804 North Creek Parkway, Suite 100, Bothell, Washington 98011, and Department of Biological Structure, University of Washington, Seattle, Washington 98195 Cite this: J. Chem. Inf. Comput. Sci. 2001, 41, 2, 233–245Publication Date (Web):January 30, 2001Publication History Received7 October 2000Published online30 January 2001Published inissue 1 March 2001https://pubs.acs.org/doi/10.1021/ci0001482https://doi.org/10.1021/ci0001482research-articleACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views1576Altmetric-Citations185LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Antagonists,Chemical calculations,Molecules,Peptides and proteins,Pharmacophores Get e-Alerts
Crystal field effects on the topological properties of the electron density in molecular crystals: The case of urea (1994)

The Quantum Theory of Atoms in Molecules, due to Bader, is applied to periodic systems. Results for molecular and crystalline urea are presented. Changes in both bond critical points and atomic properties due to changes of chemical environment are described. A rationale for the different lengths of the in-plane and out-of-plane hydrogen bonds and for the lengthening of the CO bond in bulk urea is provided in terms of the properties of the Laplacian of the oxygen atom electron density distribution. An evaluation of molecular and atomic volume changes indicates that the decrease of molecular volume upon change of phase from gas to solid originates primarily from a contraction of the atomic basins directly involved in hydrogen bonds. Other atoms show a small expansion. The considerable decrease of oxygen and hydrogen atomic volumes is related to the mutual penetration of their van der Waals envelopes following hydrogen bond formation. The results confirm that urea is more polar in the solid phase.
Improving the iteration bound of finite state machines (2003)

A description is given of a general approach to improve beyond the given iteration bound the speed of an arbitrary synchronous finite-state machine (FSM) or a discrete-time finite-state Markov process. The methods proposed can be implemented with pipelined arrays of simple hardware modules, achieving a throughput rate on the order of the reciprocal of a single-gate delay or latch setup time, whichever is limiting, at the expense of latency. Combining the pipelined arrays and modules in parallel further increases the throughput, which is theoretically unbounded. The implemented concurrent FSM is fully efficient and has minimal overhead, where the complexity grows only linearly with the speedup. The approach is practical for FSMs with a small number of states, or other special structures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Engineering bacteriophage for a pragmatic low-resource setting bacterial diagnostic platform (2016)

Bacteriophages represent multifaceted building blocks that can be incorporated as substitutes for, or in unison with other detection methods, to create powerful new diagnostics for the detection of bacteria. The ease of phage manipulation, production, and detection speed clearly highlights that there remains unrealized opportunities to leverage these phage-based components in diagnostics amenable to resource-limited settings. The passage of regulations like the Food Safety Modernization act, and the ever increasing extent of global trade and travel, will create further demand for these types of diagnostics. While phage-based diagnostics have begun to entering the market place, further research is needed to ensure the potential benefits of phage-based technologies for public health are fully realized. We are just beginning to explore the possibilities that phage-based detection can offer us in the future. The combination of engineered phages as well as engineered enzymes could result in ultrasensitive detection systems for low-resource settings. Because the reporter enzyme is synthesized in vivo, we need to consider the options outside of normal enzyme reporters. In this case, common enzyme issues such as purification and long-term stability are less important. Phage-based diagnostics were conceptualized from out-of-the box thinking and the evolution of these systems should be as well.
Assistant agents for creation and management of distributed applications (2005)

We propose a software development toolkit named ADAM (Adaptive Distributed Applications Manager) which creates operational distributed applications. To increase the performances of these distributed applications, they are created according to the network, machines and software constraints, and are updated in reply to dynamic environment changes. Using a graphical interface, the user provides functional specifications of the distributed application he wants to build. ADAM finds out a structural scheme of this application. It adds missing software components (like data transformation software for example) in order to create an effective distributed application and selects available software components located on various machines and sites, subject to varying machine performances and different inter site distances. In a second step, the scheme is transformed into a distributed application.
Relaxation-allowed cross-peaks in two-dimensional N.M.R. correlation spectroscopy (1989)

An analysis is made of the effects of non-exponential transverse relaxation during the free precession periods of two-dimensional N.M.R. experiments. It is shown, both theoretically and experimentally, that the presence of cross-correlation between various interactions that cause relaxation, such as chemical shift anisotropy and dipole-dipole interactions, may lead to the creation of spin-ordered states that make coherence transfer processes possible in spite of the absence of scalar, dipolar or quadrupolar splittings. The principal example discussed in the context of two-dimensional correlation experiments is the occurrence of cross-peaks between two spins which are not scalar coupled to one another. The misinterpretation of these novel effects can represent a pitfall to the practising N.M.R. spectroscopist, whilst their correct interpretation may provide useful evidence about the spatial arrangement of the nuclei.
Characterization of the guinea pig lung membrane leukotriene D4 receptor solubilized in an active form. Association and dissociation with an islet-activating protein-sensitive guanine nucleotide-binding protein. (1990)

Membrane fractions from the guinea pig lung had high- and low-affinity binding sites for LTD4 with Kd values of 0.016 and 9.1 nM, respectively. In the presence of guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) or by prior treatment of the membrane with islet-activating protein (IAP), the high-affinity site shifted to a low-affinity state. Consistently, a 41-kDa protein was ADP-ribosylated by treatment of the lung membranes with IAP, and this event was inhibited by the addition of GTP gamma S. We solubilized the LTD4 receptor from the lung membranes in an active form with 5 mM 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) and 10% glycerol. On a gel filtration column, the binding activity was eluted at the volume corresponding to a Mr of 70,000 or over 500,000 in the presence or absence of Mg2+ (5-20 mM), respectively, in solubilizing buffers. The Kd value of [3H]LTD4 binding to the 70-kDa protein was similar to the low-affinity binding constant of the membrane and was insensitive to GTP gamma S. The preparation solubilized in the absence of Mg2+ showed both high- and low-affinity binding sites for LTD4, and the addition of GTP gamma S shifted the high-affinity site to a low-affinity one. Thus, 1) the LTD4 receptor is coupled to an IAP-sensitive GTP-binding protein, 2) this GTP-binding protein is dissociable from the receptor by solubilizing the lung membrane with CHAPS and Mg2+, and 3) the receptor associated to or dissociated from a GTP-binding protein exhibited a high- or low-affinity state, respectively. These data provide an insight into the molecular mechanism of regulation of the LTD4 receptor signaling process by association and dissociation with an IAP-sensitive GTP-binding protein.
Synthesis of Pyrrolo[3,2-c]pyridine and Pyrazolo[3,4-d]pyrimidine β-D-Arabinonucleosides via Nucleobase Anion Glycosylation (1991)

Abstract Ara-3,7-dideazaadenosine (la), ara-8-aza-7-deazaadenosine (lb) and the corresponding inosine derivatives 2a, b were synthesized. Nucleobase anion glycosylation was stereoselective but gave N-1 and N-2 regioisomers in case of pyrazolo[3,4-d]pyrimidines.
Collaborative Care for Adults With Congenital Heart Disease (2002)

Section on Cardiovascular Disease in the Young T he number of adults who have survived with congenital heart disease is increasing rapidly. Although prevalence studies have not been performed, estimates of expected numbers of people reaching adulthood with congenital heart disease (CHD) can now be made because birth prevalence has been studied and mortality rates have begun to stabilize. Birth prevalence for all forms of congenital heart disease detected in the first year of life is estimated at 8.1 per thousand live births on the basis of data from the Centers for Disease Control 1 ; estimates for disease of sufficient severity to result in a catheterization, surgery, or death in the first year of life are 2.3 per thousand, using population-based data derived from the Pediatric Cardiac Care Consortium. Estimates of numbers of individuals reaching adulthood born in 1990 with congenital heart disease of sufficient severity to be diagnosed or treated during the first year of life are shown in the Figure . Disregarding all patients born before 1990 and those not diagnosed in the first year and assuming stable mortality in early adulthood, by 2020, nearly 760 000 individuals will have CHD, with 200 000 in the more severe subgroup.
Controlling the thickness of hollow polymeric microspheres prepared by electrohydrodynamic atomization (2010)

In this study, the ability to control the shell thickness of hollow polymeric microspheres prepared using electrohydrodynamic processing at ambient temperature was investigated. Polymethylsilsesquioxane (PMSQ) was used as a model material for the microsphere shell encapsulating a core of liquid perfluorohexane (PFH). The microspheres were characterized by Fourier transform infrared spectroscopy and optical and electron microscopy, and the effects of the processing parameters (flow-rate ratio, polymer concentration and applied voltage) on the mean microsphere diameter (D) and shell thickness (t) were determined. It was found that the mean diameters of the hollow microspheres could be controlled in the range from 310 to 1000 nm while the corresponding mean shell thickness varied from 40 to 95 nm. The results indicate that the ratio D : t varied with polymer concentration, with the largest value of approximately 10 achieved with a solution containing 18 wt% of the polymer, while the smallest value (6.6) was obtained at 36 wt%. For polymer concentrations above 63 wt%, hollow microspheres could not be generated, but instead PMSQ fibres encapsulating PFH liquid were obtained.
Screening method for detection of drugs of abuse in human urine. (1971)

A simple, convenient method is described for the detection in human urine of three major classes of drugs of abuse: amphetamines, barbiturates, and alkaloids. The drugs are adsorbed from urine by a column of non-ionic resin (Amberlite XAD-2), eluted with methanol, and chromatographed on a thin-layer silica gel plate. The drugs are made visible and identified by a series of procedures involving exposure to ultraviolet radiation, heat treatment, sequential spraying with group-specific reagents, and measurement of Rf values. Detection limits for 5-ml urine specimens are: 0.4 µg per ml for amphetamines and barbiturates, and 0.8 g per ml for alkaloids. The test requires 6 h to perform. One technologist can process 50 specimens per day.
Numerical analysis of acoustical field on AOTFs with weighted coupling (2008)

A new approach based on the finite element-artificial transmitting boundary method is presented, and the 2-D acoustical field on the substrate region is calculated by using this method.
Total Synthesis of Epothilones B and D: Stannane Equivalents for β-Keto Ester Dianions (2008)

Studies leading to a total synthesis of epothilones B and D are described. The overall synthetic plan was based on late-stage fragment assembly of two segments representing C(1)-C(9) and C(10)-C(21) of the structure. The C(1)-C(9) fragment was prepared by elaboration of commercially available (2R)-3-hydroxy-2-methylpropanoate at both ends of the three-carbon unit. Introduction of carbons 1-4 containing the gem-dimethyl unit was achieved in a convergent manner using a diastereoselective addition of a stannane equivalent of a beta-keto ester dianion. An enantioselective addition of such a stannane equivalent for a beta-keto ester dianion was also used to fashion one version of the C(10)-C(21) subunit; however, the fragment assembly (using bimolecular esterification followed by ring-closing metathesis) with this subunit failed. Therefore, fragment assembly was achieved using a Wittig reaction; this was followed by macrolactonization to close the macrocycle. The C(10)-C(21) subunit needed for this approach was prepared in an efficient manner using the Corey-Kim reaction as a key element. Other key reactions in the synthesis include a stereoselective SmI(2) reduction of a beta-hydroxy ketone and a critical opening of a valerolactone with aniline which required extensive investigation.
Ultrasound exfoliation of inorganic analogues of graphene (2014)

High-intensity ultrasound exfoliation of a bulk-layered material is an attractive route for large-scale preparation of monolayers. The monolayer slices could potentially be prepared with a high yield (up to 100%) in a few minutes. Exfoliation of natural minerals (such as tungstenite and molybdenite) or bulk synthetic materials (including hexagonal boron nitride (h-BN), hexagonal boron carbon nitride (h-BCN), and graphitic carbon nitride (g-C3N4)) in liquids leads to the breakdown of the 3D graphitic structure into a 2D structure; the efficiency of this process is highly dependent upon the physical effects of the ultrasound. Atomic force microscopy (AFM), transmission electron microscopy (TEM), and selected area electron diffraction (SAED) were employed to verify the quality of the exfoliation. Herein, this new method of exfoliation with ultrasound assistance for application to mono- and bilayered materials in hydrophobic and hydrophilic environments is presented.
The Influence of Thick Inhomogeneities on Charged Particle Beams (1978)

Monte Carlo calculations have been performed for charged particle beams incident on density discontinuities which extend for a substantial portion of the particle range. We present dose distributions for energy-modulated proton beams incident on long slivers of bone in tissue. The influence of sliver width and length, and of the angular divergence of the beam, is investigated. Comparable dose distributions are also presented for a pi-meson beam. The significance of the results is related to the problem of assessing the spatial resolution necessary in the measurement of densities in inhomogeneous media in order to guide charged particle radiotherapy.
pH-Controlled Macromolecule Encapsulation in and Release from Polyelectrolyte Multilayer Nanocapsules (2001)

pH-Controlled encapsulation in and release of macromolecules from polyelectrolyte capsules of a few microns in diameter is demonstrated. Capsules were prepared via alternating adsorption of the oppositely charged polymers poly(allylamine hydrochloride) and poly(styrene sulfonate) onto decomposable melamin formaldehyde cores. The capsules were open for macromolecules at pH values below 6 and closed at pH > 8.
An Approach of Quality of Service Assurance for Enterprise Cloud Computing (QoSAECC) (2014)

Enterprise Cloud Computing (ECC) is a new trend for IT service provisioning due to the concerns of cost down and increase of Quality of Service (QoS). However, there are many obstacles to the services moving from traditional enterprise computing to cloud environment, such as how to assure the quality of services, security, data availability, data privacy, etc. In order to support the risk free migration of IT provisioning for enterprises from traditional enterprise architecture to cloud computing, an integrated solution is urgently needed. In this paper, we propose a formal model, to assist not only the ECC services design and construction through SaaS, PaaS, IaaS, but also the simultaneous monitoring and dynamic analysis on the QoS factors for the promises from QoS service providers, such as security, performance, timeliness, throughput, reliability, and the service level agreements (SLAs) for multiple ECC consumers. Based on the formal model, analysis model and testing model can be generated consequently to support automatic testing as well as run time monitoring to assure the satisfaction to the requirements/SLAs constraints.
Photothermal radiometry measurement of thermal diffusivity (1990)

A method of measuring the thermal diffusivity of solid material at room temperature with photothermal radiometry is described. By measuring the amplitude and phase frequency characteristics of the photothermal signal, the thermal diffusivity is calculated and compared with the value obtained by the pulsed laser conductometer method.
Glucose- and pH-Responsive Charge-Reversal Surfaces (2014)

We have shown a pH- and glucose-responsive charge reversal on silica surface through heterogeneous functionalization utilizing amines and boronic acid moieties. The dual responsiveness of the charge reversal has been unambiguously demonstrated through the desorption of charged chromophores. Interestingly, we observed a concentration-dependent desorption response to glucose at physiologically relevant levels.
Studies on the oxidation of N-substituted-dibenz(b,f)azepines. I. Oxidation with m-chloroperbenzoic acid. (1981)

Oxidation of various N-substituted-dibenz [b, f] azepines with m-chloroperbenzoic acid (m-CPBA) was examined. Oxidation of N-acyldibenz [b, f] azepines (If-k) gave the 10, 11-oxide (XVIIf-k). Oxidation of N-alkyldibenz [b, f] azepines (Ia-c) gave the diphenylamine (IIa-c) and 9-acridone (IIIa-c). Oxidation of N-methyldibenz [b, f]-azepine (Id) gave the N-oxide (IX) as a main product. In the case of oxidation of N-phenyldibenz [b, f] azepine (Ie), hydroxylation of the phenyl nucleus occurred to give N-(o-hydroxy) phenyldibenz [b, f] azepine (XII). In addition, further oxidation of XII proceeded to give diphenylamine (IIe). The rates of oxidation of N-substituted-dibenz [b, f] azepines (Ia-c) having an N-alkyl group were faster than those of If-k (having an N-acyl group).
Common Fixed Point Theorems in Fuzzy Metric Spaces under Implicit Relations (2015)

In this paper using the concept of a pair $(A, B)$ being weakly $A$-compatible, we prove a common fixed point theorem for self maps in fuzzy metric spaces which modifies and generalizes some known results. On the other hand a common fixed point theorem for self maps in sequentially compact fuzzy metric spaces is also proved.
Más notas sobre la familia López de Zárate (1955)

Patients with DISH have a lower pain threshold than patients who do not have DISH. TP count and TTS correlate with the functional status, BMI, waist circumference, and high-grade BB. No correlation was observed between pain threshold and MS.
Visual correction of orientation error for a mobile robot (2003)

A mobile robot operating in a real world environment rarely achieves the theoretical accuracy in positioning that is possible despite the use of precise manufacturing and high resolution encoders in drive motors. This is due to internal errors to a small degree, but mainly caused by minor variations in floor flatness. A vision system is developed and implemented for a mobile robot to correct orientation errors. Straight line ceiling features are used for reference orientation during navigation. An efficient and robust algorithm is developed, tested extensively and implemented in a mobile robot for actual navigation experiments. Preliminary experimental results show that simple visual servoing with proportional control can already achieve significant improvements.
Ordering the attributes of query results (2006)

There has been a great deal of interest in the past few years on ranking of results of queries on structured databases, including work on probabilistic information retrieval, rank aggregation, and algorithms for merging of ordered lists. In many applications, for example sales of homes, used cars or electronic goods, data items have a very large number of attributes. When displaying a (ranked) list of items to users, only a few attributes can be shown. Traditionally, these are selected manually. We argue that automatic selection of attributes is required to deal with different requirements of different users. We formulate the problem as an optimization problem of choosing the most "useful" set of attributes, that is, the attributes that are most influential in the ranking of the items. We discuss different variants of our notion of attribute usefulness, and propose a hybrid Split-Pane approach that returns a composite of the top attributes of each variant. We conduct both a performance and a user study illustrating the benefits of our algorithms in terms of efficiency and quality of explanation.