gebhart/patrepeval huggingface dataset:
CIUDAD Y ESPACIO PÚBLICO (2006)

Hace decadas distintos centros urbanos han estado envueltos en procesos de cambios, siendo sometidos a proyectos de renovacion, revitalizacion, rehabilitacion o regeneracion urbana. Estos procesos de cambio, llevados a cabo en los centros urbanos, son originados basicamente por los procesos de deterioro que estos experimentan, lo cual puede ser reconocido a simple vista en su estructura urbana. El deterioro en la estructura urbana queda manifestado en la significativa cantidad de predios baldios, la ineficiente conectividad al resto de la ciudad, los inapropiados usos de suelo, el espacio publico sub-utilizado y carente de programa. Por otra parte, la obsolescencia de los centros se manifiesta tambien en que estos dejan de responder a la demanda funcional, social y economica de las condiciones actuales de su ciudad, donde es frecuente encontrar diferentes actividades que no tienen necesariamente relacion entre ellas.
The History of Injectable Silicone Fluids for Soft-Tissue Augmentation (2007)

A better understanding of the history of injectable silicone fluids for soft-tissue augmentation can give insight into the pitfalls and complications surrounding its use. There has been an evolution in the technique and type of products used for soft-tissue augmentation. In its current use, silicone oil for permanent soft-tissue augmentation could be a very powerful tool. There is some literature that supports the use of a small amount of purified, high-viscosity silicone oil; however, there has not been a single longitudinal study to date with appropriate follow-up data. The unanswered question remains: Are the risks worth the potential benefits of silicone oil as a permanent filler?
Adrenocortical Suppression in the Dog After a Single Dose of Methylprednisolone Acetate (1981)

Adrenal function was assessed in dogs after intramuscular administration of a single dose of methylprednisolone acetate (MPA). Twelve dogs were test challenged with adrenocorticotropic hormone (ACTH) and then assigned randomly to 1 of 3 groups and given MPA. Individual groups were test challenged with ACTH 2, 3, or 4 weeks later. All dogs were rechallenged 5 weeks after MPA administration. Plasma cortisol concentration was determined by radioimmunoassay. Basal plasma cortisol (time 0) was depressed on weeks 2 and 3, but not on weeks 4 and 5. Adrenal response to ACTH (increment of cortisol change) was suppressed on weeks 2, 4, and 5, but not on week 3. It was concluded that a single dose of MPA is capable of altering adrenal cortical function in dogs for at least 5 weeks.
A PRELIMINARY ANTIHYPERGLYCEMIC AND ANTINOCICEPTIVE ACTIVITY EVALUATION OF AMORPHOPHALLUS CAMPANULATUS CORMS (2014)

Objective: The objective of the present study was to evaluate the antihyperglycemic and antinociceptive potential of methanol extract of Amorphophallus campanulatus corms in Swiss albino mice. Methods: Antihyperglycemic acivity was determined through oral glucose tolerance tests in glucose-loaded mice. Antinociceptive activity was determined through intraperitoneally administered acetic acid induced pain model in mice. Results: The extract, when administered to mice at doses of 50, 100, 200 and 400 mg per kg body weight, dose-dependently reduced blood glucose levels in glucose-loaded mice, respectively, by 28.8, 29.1, 35.3, and 37.4%. A standard antihyperglycemic drug, glibenclamide, when administered at a dose of 10 mg per kg body weight reduced blood glucose level by 40.7%. Thus the extract, at the highest dose tested, showed a near equivalent antihyperglycemic potency to that of glibenclamide. At the afore-mentioned four doses, the extract reduced the number of abdominal constrictions induced by intraperitoneal administration of acetic acid in mice by 30.4, 33.3, 42.4, and 45.5%, respectively. By comparison, a standard antinociceptive drug, aspirin, when administered to mice at doses of 200 and 400 mg per kg body weight, reduced the number of abdominal constrictions by 27.3 and 36.4%, respectively, demonstrating that the extract, even at the lowest dose, was more potent than the lower dose of aspirin. Conclusion: The results suggest that corms of the plant possess constituents with antihyperglycemic and antinociceptive activities, and which merits further isolation and identification.
Identification and characterization of two critical sequences in SV40PolyA that activate the green fluorescent protein reporter gene (2011)

Alu repeats or Line-1-ORF2 (ORF2) inhibit expression of the green fluorescent protein (GFP) gene when inserted downstream of this gene in the vector pEGFP-C1. In this work, we studied cis-acting elements that eliminated the repression of GFP gene expression induced by Alu and ORF2 and sequence characteristics of these elements. We found that sense and antisense PolyA of simian virus 40 (SV40PolyA, 240 bp) eliminated the repression of GFP gene expression when inserted between the GFP gene and the Alu (283 bp) repeats or ORF2 (3825 bp) in pAlu14 (14 tandem Alu repeats were inserted downstream of the GFP gene in the vector pEGFP-C1) or pORF2. Antisense SV40PolyA (PolyAas) induced stronger gene expression than its sense orientation (PolyA). Of four 60-bp segments of PolyAas (1F1R, 2F2R, 3F3R and 4F4R) inserted independently into pAlu14, only two (2F2R and 3F3R) eliminated the inhibition of GFP gene expression induced by Alu repeats. Deletion analysis revealed that a 17 nucleotide AT repeat (17ntAT; 5'-AAAAAAATGCTTTATTT-3') in 2F2R and the fragment 3F38d9 (5'-ATAAACAAGTTAACAACA ACAATTGCATT-3') in 3F3R were critical sequences for activating the GFP gene. Sequence and structural analyses showed that 17ntAT and 3F38d9 included imperfect palindromes and may form a variety of unstable stem-loops. We suggest that the presence of imperfect palindromes and unstable stem-loops in DNA enhancer elements plays an important role in GFP gene activation.
The Gas Turbine Engine: Design, Development, Applications (1975)

The gas turbine engine: design, development, applications , The gas turbine engine: design, development, applications , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
A microprocessor controlled automatic sun tracker (1991)

A microprocessor-based automatic sun-tracking system is proposed. This unit controls the movement of a solar panel that rotates and follows the motion of the sun. There are two limit switches attached to the panel to mark its maximum angular positions in the east and west. The status of the limit switches is read by the microprocessor and indicates that the maximum angular position in either direction has been reached and the panel should not be driven any further. As the plane of the panel is always kept normal to the direction of the sun, maximum thermal energy is obtained from the solar panels.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Impact of a DDoS attack on computer systems: An approach based on an attack tree model (2018)

Attacks that deny access to a service provider can occur anytime, anywhere, and most usually occur with little or no warning. Many small and midsize companies are not prepared to handle a significant outage. For an enterprise to face up to an attack of this type, it must possess a bandwidth higher than that of the attack, an infrastructure with redundant components, regular backups, firewalls for monitoring the threats and other proactive and reactive mechanisms. Otherwise, the service will be interrupted, increasing the chances of financial losses. Hierarchical modeling approaches are often used to evaluate the availability of such systems, thereby leveraging the representation of multiple failure and repair events in distinct parts of the system. This paper evaluates the impact of a distributed denial-of-service attack in computer systems. We propose hierarchical models that represent the behavior of major system components and assess the effects of a DDoS attack on the system availability. The equations that estimate the likelihood of an attack, attacker benefits, feasibility, the pain factor and the propensity of the offense were present. They enable a direct analytical solution for large systems. The results obtained from the attack tree analysis allow to plan and improve system's availability, maintainability, and reliability. The attack tree indices show the impact of simultaneous attacks on a computer system and the several threats which will maximize the system downtime.
Sequences Responsible for Transcription Termination on a Gene Segment in <i>Saccharomyces cerevisiae</i> (1984)

We have mapped a signal sequence for mRNA 3'-end formation in Saccharomyces cerevisiae by using a Drosophila melanogaster DNA segment that complements a yeast adenine-8 mutation. That the 3' end of the transcript in S. cerevisiae nearly coincides with that in D. melanogaster is consistent with the possibility that mRNA termini are similarly determined in both organisms. Deletion analysis reveals that the complete signal is no more than 21 base pairs long. Part of the signal is the sequence TTTTTATA, which is seen in the termination region of several yeast genes. TTTTTATA appears to be able to act autonomously as a partial termination signal. The efficiency of the complete signal is affected by substitution of sequences downstream from it. This modulation of the effect of a signal is consistent with termination in S. cerevisiae, resembling rho-dependent termination in bacteria.
Immunoregulation in experimental murine candidiasis: specific suppression induced by Candida albicans cell wall glycoprotein (1985)

Immune regulation in candidiasis is inferred from studies of both human and animal infection, with a suppressive role suggested for cell wall polysaccharide. To study the immunosuppressive potential of Candida albicans in a murine model, whole blastoconidia or purified cell wall components of C. albicans were tested for their effects on the development of acquired immune responses by superimposing a pretreatment regimen upon an established immunization protocol. CBA/J or BALB/cByJ mice were pretreated twice intravenously with 100 micrograms of mannan (MAN), 100 or 200 micrograms of glycoprotein (GP), or 5 X 10(7) heat-killed C. albicans blastoconidia, followed 1 week later by an immunization protocol of two cutaneous inoculations of viable C. albicans blastoconidia given 2 weeks apart. Delayed hypersensitivity (DTH) to GP or to a membrane-derived antigen, B-HEX, was tested 7 days after the second inoculation, and lymphocyte stimulation was tested with mitogens and Candida antigens after 12 days. To assess protection, mice were challenged intravenously with viable C. albicans blastoconidia 14 days after the second cutaneous inoculation and sacrificed 28 days later for quantitative culture of kidneys and brains. Sera were obtained for enzyme-linked immunosorbent assays at selected intervals. Pretreatment with GP resulted in specific in vivo suppression of DTH to GP but not to B-HEX antigen and specific in vitro suppression of lymphocyte stimulation to GP but not to other Candida antigens or mitogens. MAN and heat-killed C. albicans blastoconidia had no such effects. GP pretreatment also diminished the protective effect of immunization against challenge, demonstrable in the brain, while not altering significantly the production of antibody in response to infection. Contrary to clinical evidence, MAN was not immunosuppressive in this model, and in fact, the immunosuppressive potential of GP, which is composed largely of MAN, was found to be dependent upon the presence of its heat-labile protein moiety.
Reduction to Homozygosity of Genes on Chromosome 11 in Human Breast Neoplasia (1987)

The somatic loss of heterozygosity for normal alleles occurring in human tumors has suggested the presence of recessive oncogenes. The results presented here demonstrate a loss of heterozygosity of several genes on chromosome 11 in primary breast tumors. Restriction fragment length polymorphism analysis of these DNAs further suggests that the most frequent loss of sequences in breast tumors occurs between the beta-globin and parathyroid hormone loci on the short arm of chromosome 11. The loss of heterozygosity for chromosome 11 loci has a significant association with tumors that lack estrogen and progesterone receptors, grade III tumors, and distal metastasis.
Traumatic Brain Injury (2002)

Abstract Traumatic Brain Injury (TBI) is a devastating medical condition mat can happen to anyone at anytime, despite precautions. This paper provides details regarding etiology, symptoms, prognosis, and treatment of TBI. Patients and families usually require assistance and direction from several healthcare professionals, including social workers, both during and after the initial period of hospitalization and rehabilitation. After a brief discussion of interventions at several levels, the paper concludes with a focus on both the individual and the family, and how social workers in the hospital or rehabilitation clinic can intervene to assist the patient and family members in learning and using more effective methods of coping. Implications for social work practice are included.
Structure of the rabbit fast-twitch skeletal muscle Ca2+-ATPase gene. (1988)

We have isolated two genomic clones which together encode the Ca2+-ATPase of rabbit fast-twitch skeletal muscle sarcoplasmic reticulum. One of the two 16.5 kilobase (kb) genomic inserts in the lambda phage vector Charon 4A contains 23 exons extending from the polyadenylation site at the 3' end of the ATPase gene to within 38 nucleotides of the translation initiation codon in the 5' exon. An overlapping genomic insert of 16.5 kb contains the remainder of the 5' exon and a further 8 kb of upstream sequence. S1 nuclease mapping and primer extension analysis of the 5' end of the Ca2+-ATPase mRNA indicate that the transcription initiation site is located 185 base pairs (bp) upstream of the translation initiation codon. A "TATA" box (CA-TAAA) was found at position -30 and the sequence CCAAT was found at position -78 relative to the transcription initiation site. In a previous study (Brandl, C. J., de Leon, S., Martin, D. R., and MacLennan, D. H. (1987) J. Biol. Chem. 262, 3768-3774) cDNAs for neonatal and adult forms of the fast-twitch Ca2+-ATPase were shown to encode different carboxyl-terminal sequences, presumably as a result of alternative splicing. We have now found that these different DNA sequences encoding different carboxyl-terminal sequences are located in different exons. Exon boundaries of the Ca2+-ATPase gene did not correlate well with proposed domain boundaries for the Ca2+-ATPase protein. The locations of exon/intron boundaries were only partially conserved between the Ca2+-ATPase gene and a Na+/K+-ATPase gene (Ovchinnikov, Y. A., Monastyrskaya, G. S., Broude, N. E., Allikmets, R. L., Ushkaryov, Y. A., Melkov, A. M., Smirnov, Y. V., Malyshev, I. V., Dulubova, I. E., Petrukhin, K. E., Gryshin, A. V., Sverdlov, V. E., Kiyatkin, N. I., Kostina, M. B., Modyanov, N. N., and Sverdlov, E. D. (1987) FEBS Lett. 213, 73-80) and they did not follow closely the boundaries of amino acid sequences that are highly conserved among a group of ion transport ATPases.
Preparation of body armour material of Kevlar fabric treated with colloidal silica nanocomposite (2008)

To safeguard bodies of soldiers better, including their necks and joints, a novel armour material was exploited using nanocomposite. Compared with traditional armour materials, this new material possessed superior barrier property and more comfortable characteristics. The new armour material was made of Kevlar cloth and shear thickening fluid (STF). Colloidal silica particles were first synthesised via the Stöber synthesis method and then they were used to prepare a suspension with solvent of polyethylene glycol 200. At last, Kevlar cloth was treated with the suspension and the resultant was named as STF–Kevlar nanocomposite. In this process, the particle sizes were characterised with scanning electron microscopy. The rheological properties were measured with a Physica MCR301 stress controlled rheometer. The results showed that the silica particles could be determined to be monodispersed spherical particles. The suspension, named the shear thickening fluid, had shear thickening characteristic. The property of multilayer STF–Kevlar nanocomposite targets was compared to that of the neat Kevlar cloth and the results indicated that the STF–Kevlar nanocomposite had an improvement in barrier property and was more flexible and comfortable. The mechanism that could improve the barrier property of STF–Kevlar was briefly explained.
1.25 /spl mu/m Deep-Groove-Isolated Self-Aligned Bipolar Circuits (1982)

This paper concerns the design and characteristics of the high-performance bipolar switching devices and circuits for digital applications at lithographic dimensions of about 1 /spl mu/m. The impurity profile of the transistors is optimized for speed while maintaining sufficient current gain and punchthrough voltage. The circuits were fabricated on epitaxial wafers of a 0.5 /spl mu/m flat zone in an advanced bipolar technology featuring self-aligned polysilicon base and emitter contacts, deep-groove device isolation, and electron beam lithography. The experimental results show that n-p-n transistors exhibit a current gain greater than 40 at current densities as high as 1.3 mA//spl mu/m/sup 2/. As a result of reduced line width and polysilicon contacts, the current gain of Iateral epi-base p-n-p transistors is greater than 20 at low-current levels and remains greater than 1 at a current density as high as 0.12 mA//spl mu/m emitter edge. ECL (FI = FO = 1) circuits show a gate delay as low as 114 pS at a power dissipation of 4.9 mW. High-density I/sup 2/L/MTL circuits (average FI = 2, FO = 2.5, C/sub w/ = 90 fF) show delay of 0.91 ns at 0.17 mW. These results demonstrate that the present bipolar technology provides not only high-speed circuits, but also circuits for VLSI applications with density comparable to MOSFET.
Advances in Computer Methods for Systematic Biology: Artificial Intelligence, Data-Bases, Computer Vision. (1994)

In this book, Renaud Fortuner brings together a group of leading authorities to explore the application of artificial intelligence and other modern computer methods to that branch of biology known as systematics - the field of study aimed at identifying and classifying organisms and reconstructing their evolutionary relationships. The book begins with an overview of artificial intelligence and its applications in biology and medicine. Subsequent chapters then focus on four main areas of computer applications to systematics: methods of phylogenetic reconstruction; identification of biological specimens through computerized reasoning paths known as expert systems; the use of databases; and machine vision, that is, the computerized recording and analysis of the physical features of organisms. The sections are prefaced by tutorial chapters presenting current problems in systematics along with possible computer solutions. Based on the 1990 AR TISYST conference sponsored by the National Science Foundation, with recommendations for future funding, the volume is both a comprehensive treatmetn of state-of-the-art research in computer science and systematic biology and a practical guide for specialists in either field who are considering possible collaboration.
Safer Deep RL with Shallow MCTS: A Case Study in Pommerman (2019)

Safe reinforcement learning has many variants and it is still an open research problem. Here, we focus on how to use action guidance by means of a non-expert demonstrator to avoid catastrophic events in a domain with sparse, delayed, and deceptive rewards: the recently-proposed multi-agent benchmark of Pommerman. This domain is very challenging for reinforcement learning (RL) --- past work has shown that model-free RL algorithms fail to achieve significant learning. In this paper, we shed light into the reasons behind this failure by exemplifying and analyzing the high rate of catastrophic events (i.e., suicides) that happen under random exploration in this domain. While model-free random exploration is typically futile, we propose a new framework where even a non-expert simulated demonstrator, e.g., planning algorithms such as Monte Carlo tree search with small number of rollouts, can be integrated to asynchronous distributed deep reinforcement learning methods. Compared to vanilla deep RL algorithms, our proposed methods both learn faster and converge to better policies on a two-player mini version of the Pommerman game.
Short-term ingestion of chlorogenic or caffeic acids decreases zinc but not copper absorption in rats, utilization of stable isotopes and inductively-coupled plasma mass spectrometry technique (1998)

The amount of dietary trace elements absorbed from a meal depends, among other factors, on the quantities of certain minor plant constituents present in the meal. These substances can act as ligands and bind trace elements in the digestive tract in available or unavailable forms for absorption. The present study was designed to investigate the extent to which different polyphenols (PP) may influence Zn and Cu absorption in rats. Different PP of nutritional interest (chlorogenic acid, caffeic acid, catechin and rutin) were studied using meals extrinsically-labelled with stable isotopes 67Zn and 65Cu. Male Wistar rats were fed on a non-labelled semi-synthetic diet containing (mg/kg) 38 Fe, 35 Zn and 7.5 Cu for 8 d. PP were dissolved in dimethyl sulfoxide as the solvent and added to the meal at 1 g/kg during 3 d before isotope administration and until the end of the experiment (a further 3 d). The control group received the dimethyl sulfoxide only. After overnight food deprivation, rats were fed on the labelled test meals (4 g diet +0.1 mg 67Zn and 0.1 mg 65Cu) with 0.5 mg Dy as a faecal marker. Faeces and urine pools were collected for 3 d and analysed for 67Zn and 65Cu isotopic enrichment using the inductively-coupled plasma mass spectrometry technique. Zn absorption was significantly less in rats fed on chlorogenic acid or caffeic acid than in the control group. Catechin ingestion non-significantly inhibited 67Zn absorption. However, the PP studied were without effect on Cu absorption. The study illustrates the effect of metal-binding phenolic compounds on mineral nutrition in the rat, and the possible importance of the effects of different foods rich in these compounds on mineral absorption in man.
Intestinal, segmented, filamentous bacteria in a wide range of vertebrate species (1993)

Segmented, filamentous bacteria (SFBs) form a group of bacteria with similar morphology and are identified on the basis of their morphology only. The relationships of these organisms are unclear as the application of formal taxonomic criteria is impossible currently due to the lack of an in vitro technique to culture SFBs. The intestine of laboratory animals such as mice, rats, chickens, dogs, cats and pigs is known to harbour SFBs. To see whether this extends to other animal species, intestines from 18 vertebrate species, including man, were examined. SFBs were detected with light microscopy in the cat, dog, rhesus monkey, crab-eating macaque, domestic fowl, South African claw-footed toad, carp, man, laboratory mouse and rat, wood mouse, jackdaw and magpie. These results suggest that non-pathogenic SFBs are ubiquitous in the animal kingdom. Among apparently identical animals, there was considerable variation in the degree of SFB colonization. It is suggested that SFB colonization could serve as a criterion of standardization of laboratory animals.