gebhart/patrepeval huggingface dataset:
Reciprocal Ferrite Devices in TEM Mode Transmission Lines (1958)

Several new reciprocal ferrite devices have been designed in TEM mode transmission lines to operate over both narrow and extremely broad bandwidths in the low-microwave frequency region. These include variable attenuators, an amplitude modulator, and a traveling-wave tube equalizer. Each component utilizes the attenuation associated with gyromagnetic resonance in low saturation magnetization ferrites. The techniques used to overcome the matching problems inherent in TEM mode transmission lines when ferrite loaded, and the design considerations pertinent to each component, are treated in detail. The parameters affecting the characteristics of each device are discussed and both final design and operating characteristics of the components are presented.
Clustering and switching in semantic fluency: predictors of the development of Alzheimer's disease (2008)

Subjects with memory complaints and AD patients have an alteration in both qualitative and quantitative aspects of semantic fluency. A clustering analysis could enhance the reliability of early AD diagnosis.
Models of ensemble firing of muscle spindle afferents recorded during normal locomotion in cats (1998)

1. The aim of this work was to compare the ability of several mathematical models to predict the firing characteristics of muscle spindle primary afferents recorded chronically during normal stepping in cats. 2. Ensemble firing profiles of nine hamstring spindle primary (presumed group Ia) afferents were compiled from stored data from 132 step cycles. Three sets of profiles corresponding to slow, medium and fast steps were generated by averaging groups of step cycles aligned to peak muscle length in each cycle. 3. Five models obtained from the literature were compared. Each of these models was used to predict the spindle firing profiles from the averaged muscle length signals. The models were also used in the reverse direction, namely to predict muscle length from the firing profiles. A sixth model incorporating some key aspects of the other models was also included in the comparisons. 4. Five of the models predicted spindle firing well, with root mean square (r.m.s.) errors lower than 14 % of the modulation depth of the target profiles. The key variable in achieving good predictions was muscle velocity, the best fits being obtained with power-law functions of velocity, with an exponent of 0.5 or 0.6 (i.e. spindle firing rate is approximately proportional to the square root of muscle velocity). The fits were slightly improved by adding small components of EMG signal to mimic fusimotor action linked to muscle activation. The modest relative size of EMG-linked fusimotor action may be related to the fact that hamstring muscles are not strongly recruited in stepping. 5. Length was predicted very accurately from firing profiles with the inverse of the above models, indicating that the nervous system could in principle process spindle firing in a relatively simple way to give accurate information on muscle length. 6. The responses of the models to standard ramp-and-hold displacements at 10 mm s-1 were also studied (i.e. velocities that were an order of magnitude lower than that during stepping). In these cases components of spindle primary response related to length as well as velocity were needed for good fits. Because these length-related components detracted from rather than improved predictions of the step cycle data, an attenuation of length dependence at high muscle velocities emerged as a possibility. 7. We conclude that in this study we have identified models and parameters that may be used to predict spindle afferent firing from the time course of muscle length in the cat step cycle.
Evaluation of Micro Structured Glass Layers as Dielectric-and Passivation Material for Wafer Level Integrated Thin Film Capacitors and Resistors (2007)

This work describes the integration of thin micro-structured glass layers into copper / benzocyclobutene (Cu/BCB) thin film multi layer. The glass, which is deposited by a low temperature PVD-PIAD process (physical vapor deposition with plasma ion assisted deposition) using special synthesized targets, was evaluated to act as local dielectric and passivation material for integrated capacitors and resistors. Metal-insulator-metal (MIM) capacitors and micro strip resonators were realized to determine the breakdown voltage as well as the dielectric constant of the material. Furthermore the glass material was used as passivation for integrated nickel-chromium (NiCr) resistors, which were evaluated regarding their maximum applicable current density, temperature coefficient of resistance as well as long-term stability. The first chapters of this paper describe the glass deposition and structuring as well as the integration of these processes into the Cu/BCB redistribution process of Fraunhofer IZM. Afterwards the fabrication of the test structures and the results from their characterization are discussed in detail.
BCC-Phased PdCu Alloy as a Highly Active Electrocatalyst for Hydrogen Oxidation in Alkaline Electrolytes (2018)

Anion-exchange membrane fuel cells hold promise to greatly reduce cost by employing nonprecious metal cathode catalysts. More efficient anode catalysts are needed, however, to improve the sluggish hydrogen oxidation reaction in alkaline electrolytes. We report that BCC-phased PdCu alloy nanoparticles, synthesized via a wet-chemistry method with a critical thermal treatment, exhibit up to 20-fold HOR improvement in both mass and specific activities, compared with the FCC-phased PdCu counterparts. HOR activity of the BCC-phased PdCu is 4 times or 2 times that of Pd/C or Pt/C, respectively, in the same alkaline electrolyte. In situ HE-XRD measurements reveal that the transformation of PdCu crystalline structure favors, at low annealing temperature (<300 °C), the formation of FCC structure. At higher annealing temperatures (300-500 °C), a BCC structure dominates the PdCu NPs. Density functional theory (DFT) computations unravel a similar H binding strength and a much stronger OH binding of the PdCu BCC surface (cf. FCC surface), both of which are simultaneously close to those of Pt surfaces. The synergistic optimization of both H and OH binding strengths is responsible for the enhancement of HOR activity on BCC-phased PdCu, which could serve as an efficient anode catalyst for anion-exchange membrane fuel cells. This work might open a new route to develop efficient HOR catalysts from the perspective of crystalline structure transformation.
Efficacy and Safety of Ex Vivo Cultured Adult Human Mesenchymal Stem Cells (Prochymal™) in Pediatric Patients with Severe Refractory Acute Graft-Versus-Host Disease in a Compassionate Use Study (2010)

Preliminary studies using directed-donor ex vivo expanded human mesenchymal stem cells (hMSCs) have shown promise in the treatment of acute graft-versus-host disease (aGVHD). However, their production is cumbersome and standardization is difficult. We describe the first experience of using a premanufactured, universal donor, formulation of hMSCs (Prochymal) in children (n = 12; 10 boys; 9 Caucasian; age range: 0.4-15 years) with treatment-resistant grade III and IV aGVHD who received therapy on compassionate use basis between July 2005 and June 2007 at 5 transplant centers. All patients had stage III or IV gut (GI) symptoms and half had additional liver and/or skin involvement. Disease was refractory to steroids in all cases and additionally to a median of 3 other immunosuppressive therapies. The hMSCs (8 × 10(6)cells/kg/dose in 2 patients and 2 × 10(6)cells/kg/dose in the rest) were infused intravenously over 1 hour twice a week for 4 weeks. Partial and mixed responders received subsequent weekly therapy for 4 weeks. HLA or other matching was not needed. The hMSCs were started at a median of 98 days (range: 45-237) posttransplant. A total of 124 doses were administered, with a median of 8 doses (range: 2-21) per patient. Overall, 7 (58%) patients had complete response, 2 (17%) partial response, and 3 (25%) mixed response. Complete resolution of GI symptoms occurred in 9 (75%) patients. Two patients relapsed after initial response and showed partial response to retreatment. The cumulative incidence of survival at 100 days from the initiation of Prochymal therapy was 58%. Five of 12 patients (42%) were still alive after a median follow-up of 611 days (range: 427-1111) in surviving patients. No infusional or other identifiable acute toxicity was seen in any patient. Multiple infusions of hMSCs were well tolerated and appeared to be safe in children. Clinical responses, particularly in the GI system, were seen in the majority of children with severe refractory aGVHD. Given the favorable results observed in a patient population with an otherwise grave prognosis, we conclude that hMSCs hold potential for the treatment of aGVHD, and should be further studied in phase III trials in pediatric and adult patients.
Densely spaced FDM coherent star network with optical signals confined to equally spaced frequencies (1988)

The results obtained with a fiber-optical star network using densely spaced frequency-division-multiplexing (FDM) and heterodyne detection techniques are discussed. The system consists of three optical sources transmitting around 1.28 mu m, frequency-shift keying (FSK) modulated at 45 Mb/s and spaced by 300 MHz. A 4*4 optical coupler combines the three optical signals. The FDM signals, received from one of the four outputs of the coupler, are demultiplexed by a heterodyne FM receiver. The minimum received optical power needed to obtain a bit error rate (BER) of 10/sup -9/ is -61 dBm or 113 photons/bit, which is 4.5 dB from the shot noise limit. Cochannel interference is negligible for the above channel spacing and modulation rate. The results indicate that such a system has a potential throughput of 4500 Gb/s. The results obtained with two frequency stabilization circuits used to confine these three FDM optical signals to a comb of equally spaced frequencies are also presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
An improved index sequential access method using hashed overflow (1972)

The Index Sequential Access Method (ISAM) is one of the most important file management systems used with moveable head disk devices. This study investigates the use of an unconventional method of treating overflow records. The method is to use hashing techniques to allocate space for such records. If certain conditions are satisfied, this is superior to the conventional ISAM method of chaining the overflow records via linked list techniques. These conditions are: long overflow chains with significant overflow; lack of tight disk space constraints; record keys which are small compared to the total record size; and significant use of the file in the index as opposed to the sequential mode. Using hashed overflow, the time to locate a record is dependent not on the total volume of overflow records as in conventional ISAM, but on the percentage use of space dedicated to overflow records.
Postsynthetic Metal and Ligand Exchange in MFU‐4<i>l</i>: A Screening Approach toward Functional Metal–Organic Frameworks Comprising Single‐Site Active Centers (2015)

The isomorphous partial substitution of Zn(2+) ions in the secondary building unit (SBU) of MFU-4l leads to frameworks with the general formula [M(x)Zn(5-x)Cl4(BTDD)3], in which x≈2, M = Mn(II), Fe(II), Co(II), Ni(II), or Cu(II), and BTDD = bis(1,2,3-triazolato-[4,5-b],[4',5'-i])dibenzo-[1,4]-dioxin. Subsequent exchange of chloride ligands by nitrite, nitrate, triflate, azide, isocyanate, formate, acetate, or fluoride leads to a variety of MFU-4l derivatives, which have been characterized by using XRPD, EDX, IR, UV/Vis-NIR, TGA, and gas sorption measurements. Several MFU-4l derivatives show high catalytic activity in a liquid-phase oxidation of ethylbenzene to acetophenone with air under mild conditions, among which Co- and Cu derivatives with chloride side-ligands are the most active catalysts. Upon thermal treatment, several side-ligands can be transformed selectively into reactive intermediates without destroying the framework. Thus, at 300 °C, Co(II)-azide units in the SBU of Co-MFU-4l are converted into Co(II)-isocyanate under continuous CO gas flow, involving the formation of a nitrene intermediate. The reaction of Cu(II)-fluoride units with H2 at 240 °C leads to Cu(I) and proceeds through the heterolytic cleavage of the H2 molecule.
Site specific photo-crosslinking of single stranded oligonucleotides by a complementary sequence equipped with an internal photoactive probe (1997)

The photo-crosslinking behaviour of oligonucleotide constructs, incorporating photoactive residues 1–5 at a defined position, has been examined in the presence of their DNA (14-mer) and RNA (15-mer) complementary targets using a two-fold excess; it revealed a moderate but promising irreversible binding efficiency, the results of which could be anticipated by molecular mechanics in the case of 4.
Molecular mechanics (MM2) parameters for the (.eta.3-allyl)palladium moiety (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular mechanics (MM2) parameters for the (.eta.3-allyl)palladium moietyPer Ola Norrby, Bjoern Aakermark, Fredrik Haeffner, Sverker Hansson, and Margareta BlombergCite this: J. Am. Chem. Soc. 1993, 115, 11, 4859–4867Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/ja00064a054https://doi.org/10.1021/ja00064a054research-articleACS PublicationsRequest reuse permissionsArticle Views348Altmetric-Citations55LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Type-Specificity of Immune Protection Against Shigella Paradysenteriae (Flexner) (1945)

Summary Experiments on passive protection of the chick embryo and active immunization of the mouse demonstrate the predominance of the type characterizing (“primary”) antigens of the Flexner bacillus in the immunological response of the host. Cooper’s recent data show that this is also true for man.
In vitro studies of platelet adhesion on laser‐treated polyethylene terephthalate surface (2001)

In order to improve blood compatibility, the surfaces of polyethylene terephthalate (PET) were treated using CO2 pulsed and KrF excimer lasers. The physico-chemical characterization of the laser-treated PET surfaces was carried out through attenuated total reflectance infrared spectroscopy and contact-angle measurements. The hemocompatibility of the laser-irradiated PET films was examined in vitro to evaluate their capability of inducing platelet adhesion in comparison with unmodified PET. The number of adhered platelets was determined by lactate dehydrogenase (LDH) activity measurement. Platelet adhesion on the untreated PET was relatively high compared to the laser-treated samples. Laser irradiation of PET surface reduced the number of adherent platelets and prevented platelet spreading on the surface. Reduction of platelet adhesion was attributed to the change in morphology, chemical structure, and crystallinity of the PET surface due to laser irradiation with various numbers of pulses. The morphology of adhered platelets on the PET surfaces was investigated by scanning electron microscopy (SEM). The SEM observations were consistent with the results obtained from LDH activity measurement. © 2000 John Wiley & Sons, Inc. J Biomed Mater 54: 540–546, 2001
Flow simulation in molds with preplaced fiber mats (1991)

Abstract The primary goal of this study was to develop 2‐D and 3‐D computer simulation schemes for the mold filling processes of structural reaction injection molding (SRIM) and resin transfer molding (RTM) under isothermal conditions. The developed computer code was able to simulate the mold filling in molds with complicated geometry, Experiments were also carried out based on flow vitalizations. Experimental results were compared with the numerical simulations.
Optimal control of polymer flooding for enhanced oil recovery (2013)

Polymer flooding is one of the most important technologies for enhanced oil recovery (EOR). This paper presents a development of the research on optimal control of polymer flooding. Firstly, an optimal control model of distributes parameter system (DPS) for polymer flooding is introduced which maximises the profit by adjusting the injection concentration. Necessary conditions for optimality are obtained through application of Pontryagin’s maximum principle. Then the numerical solution techniques for this OCP are summarised which include direct sequential methods and dynamic programming. Finally, conclusion remarks and further research prospects are discussed.
An analysis of STOM (ship to objective maneuver) in sea based logistics (2003)

Operational Maneuver From the Sea (OMFTS) and its implementing concept, Sea Based Logistics (SBL) stress the need for logistically supporting forces ashore directly from a sea base. This study analyzes the capability of a current LHD-class amphibious ship to sustain a force deployed ashore through direct Ship-To-Objective Maneuver (STOM) of replenishment and logistics support. We have developed a simulation model that can evaluate performance of STOM operations using an LHD-class amphibious ship as a sea base. Results indicate a substantial increase in the number of aircraft, and reliability of those aircraft, and/or a substantial reduction in sustainment requirements are needed in order to successfully accomplish the scenarios used in this study. The results of this study could support the design of future LHD-class ships.
Spreadsheet End-User Behaviour Analysis (2008)

To aid the development of spreadsheet debugging tools, a knowledge of end-users natural behaviour within the Excel environment would be advantageous. This paper details the design and application of a novel data acquisition tool, which can be used for the unobtrusive recording of end-users mouse, keyboard and Excel specific actions during the debugging of Excel spreadsheets. A debugging experiment was conducted using this data acquisition tool, and based on analysis of end-users performance and behaviour data, the authors developed a "spreadsheet cell coverage feedback" debugging tool. Results from the debugging experiment are presented in terms of enduser debugging performance and behaviour, and the outcomes of an evaluation experiment with the debugging tool are detailed.
A Method for Detecting and Measuring Frequency of Surface Vibrations Using a Helium-Neon Laser (1969)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation L. Feigen, D. MacKeen, S. Fine; A Method for Detecting and Measuring Frequency of Surface Vibrations Using a Helium‐Neon Laser. Rev. Sci. Instrum. 1 February 1969; 40 (2): 381–382. https://doi.org/10.1063/1.1683958 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioReview of Scientific Instruments Search Advanced Search |Citation Search
Теоретичні аспекти проблеми оптимізації сімейного функціонування жінок після перенесеного психотичного епізоду (2016)

The problem of primary psychotic episode, nowadays, remains extremely relevant in the practice of modern psychiatry. In the present article, the author, shows theoretical study and summarizes global data related tothis issue. The author describes main psychoemotional characteristics of women who has had a primary psychotic episode and presents the main directions in the system of complex psychopharmatherapy of the disease. Complete rehabilitation reduces the likelihood of a quick relapse and improves the patient’s clinical and social prognosis. The main role in impairment of patients’ condition and level of patients social adaptation play relatives. It can have a positive impact on the rehabilitation process through the formation of social support, which is reflected positively on the adaptation of the patient.
Multiple purine pathway enzyme activities are encoded at a single genetic locus in Drosophila. (1986)

The Drosophila melanogaster Gart locus, known from previous work to encode the enzyme activity phosphoribosylglycinamide formyltransferase (GART), specifies two alternatively processed mRNAs and two proteins. We introduced the entire Gart locus into a Drosophila tissue culture cell line in which the locus is active. The resulting cell clones contained numerous copies of the locus and overproduced both mRNAs and both expected proteins, thus markedly facilitating analysis of these molecules. We assayed extracts of the clones for the activities of 10 enzymes important for de novo purine synthesis and found that, in addition to GART, two other purine pathway activities, phosphoribosylamine-glycine ligase (phosphoribosylglycinamide synthetase, GARS) and phosphoribosylformylglycinamidine cyclo-ligase (phosphoribosylaminoimidazole synthetase, AIRS), are similarly overproduced. All three activities are present together on the larger overproduced protein. A smaller protein appears to possess only GARS activity. Therefore, alternative mRNA processing can allow cells to produce enzyme activities in forms that are either linked or unlinked to other activities.
House‐dust mite hypersensitivity, eczema, and other nonpulmonary manifestations of allergy (1998)

The pathogenetic role of house-dust mites (HDM) in atopic dermatitis (AD) remains controversial, mainly because there is no common agreement on a provocation test that mimics ordinary exposure to HDM. This is related to the lack of knowledge of the mechanism of how HDM allergens enter the body. Theoretically, there are two possible routes: directly through the epidermis, or by inhalation. In "atopy patch testing", a concentrated HDM suspension is tested on the skin under occlusion. This method is frequently used as a model of the epidermal route. The clinical relevance of this method as a provocation test for AD is discussed. As opposed to atopy patch testing, we describe another method, namely, "allergen inhalation testing", as a model of the respiratory route. Twenty patients with AD underwent bronchial provocations with HDM extract in a double-blind, randomized, placebo-controlled study. In nine out of 20 AD patients, bronchial challenge with HDM evoked skin symptoms. All patients with HDM-induced dermatitis had a history of asthma, and as a group they had a higher mean total log-transformed IgE level than the "negative skin responders". Thus, the respiratory route may be relevant in the provocation of AD in a subset of AD patients and may represent an appropriate model of provocation in these patients. Furthermore, the role of HDM in urticaria and allergic rhinitis is discussed.