gebhart/patrepeval huggingface dataset:
Generation and Characterization of Monoclonal Antibodies to the Src-Family Kinase Hck (2000)

Hck, a member of the Src-family of protein tyrosine kinases, is expressed primarily in hematopoietic cells of the myeloid and B-lymphocyte lineages. Hybridoma cell lines were established that secrete monoclonal antibodies (MAbs) to Hck. Three of the MAbs were extensively characterized and designated H7, H34, and H42. The MAbs H7 and H34 recognized an epitope within the SH3 domain of Hck, while the epitope recognized by the H42 MAb resides within the Unique domain. All three MAbs specifically recognized the p59 and p56 isoforms of Hck in transiently transfected 293T cells and in a murine macrophage cell line. Notably, the antibodies did not cross-react with other Src-family kinases tested. Under native conditions, the MAbs H34 and H42 efficiently immunoprecipitated Hck from transfected cells. Both MAbs were also successfully used for the immunofluorescent staining of Hck in intact cells.Thus, the MAbs described herein should be useful in studies of Hck function and expression.
WDM coherent star network with absolute frequency reference (1988)

A WDM coherent star network with an absolute frequency reference was demonstrated. The absolute reference was obtained from a GaInAsP DFB laser frequency-locked to atomic Ar transition at 1.2960μm. The resonant frequencies of a tunable fibre Fabry-Perot interferometer, locked to this absolute reference, were used to frequency-lock the transmitting lasers. Thus, the transmitting lasers operated at different, but fixed optical frequencies. The receiver sensitivity was not degraded by the addition of the absolute frequency reference to the network.
A web Enhaneed Course with Attendance Options (2008)

Laparoscopic technique in elective cholecystectomy is the last step in an evolutive time to minimize the abdominal access. From 1st January 2004 to 31th December 2006 we analyzed 5515 cholecystectomy procedures: 4877 laparoscopic cholecystectomy, 635 open cholecystectomy. Complications and supplementary diagnosis have been identified in SDO Lombardia's country database. Morbidity occurred in 82 patients (12.9%) with open technique and 109 patients (2.23%) with laparoscopic technique; mortality occurred in 11 patients (1.73%) with open technique and 1 patient (0.02%) with laparoscopic technique. Mean hospital stay are 14.40 days with open technique and 4.75 with laparoscopic technique. Morbidity in open technique is 6 fold more than laparoscopia technique. The difference between the two technique is present in literature and it's the result of non invasive technique compared with the incision of the laparoscopia technique. This is the critical point in the difference of hospital stay between the two technique all to the good of laparoscopy. The high mortality ratio is due to the selective criteria in laparoscopic technique. First remark is the high quality of our hospital care, compared with hospital teaching in the word. In this hospital the laparoscopic cholecystectomy is the gold standard in cholelitiasis treatment. The second remark is the limit of the open technique in severe cholelitiasis with evidence in high ratio of hospital stay, morbidity and mortality.
Residual motion compensation in ECG-gated interventional cardiac vasculature reconstruction (2013)

Three-dimensional reconstruction of cardiac vasculature from angiographic C-arm CT (rotational angiography) data is a major challenge. Motion artefacts corrupt image quality, reducing usability for diagnosis and guidance. Many state-of-the-art approaches depend on retrospective ECG-gating of projection data for image reconstruction. A trade-off has to be made regarding the size of the ECG-gating window. A large temporal window is desirable to avoid undersampling. However, residual motion will occur in a large window, causing motion artefacts. We present an algorithm to correct for residual motion. Our approach is based on a deformable 2D-2D registration between the forward projection of an initial, ECG-gated reconstruction, and the original projection data. The approach is fully automatic and does not require any complex segmentation of vasculature, or landmarks. The estimated motion is compensated for during the backprojection step of a subsequent reconstruction. We evaluated the method using the publicly available CAVAREV platform and on six human clinical datasets. We found a better visibility of structure, reduced motion artefacts, and increased sharpness of the vessels in the compensated reconstructions compared to the initial reconstructions. At the time of writing, our algorithm outperforms the leading result of the CAVAREV ranking list. For the clinical datasets, we found an average reduction of motion artefacts by 13 ± 6%. Vessel sharpness was improved by 25 ± 12% on average.
Questions About Spine Fusion Product Prompt a New Process for Reviewing Data (2011)

A convergence of peer- reviewed research, press scrutiny, federal investigations, and serendipity may lead to a clearer understanding of the safety and efficacy of a spinal fusion product manufactured by Medtronic, Inc.
Characterisation of silicone prepolymers and disparity in results (2008)

Liquid hydroxyfunctional polydimethylsiloxanes prepolymers (HOPDMS, Siloprens) with a range of relative molar masses, Mn (25 500-88 000 g/mol) quoted by the supplier have been characterised by a number of techniques such as OH group titration, bulk viscometry, Gel Permeation Chromatography (GPC), and swelling measurements. The resulting molar masses of these prepolymer obtained through these techniques have been compared with one another and that of the values quoted by the manufacturer. Unexpected results of insensitivity of the properties of these prepolymer to the initial molar masses quoted by the suppliers have been observed. It has been found out that these results are dependent upon the type of technique used. The reason for these unexpected results has been discussed in detail and attributed to the multi functionality of the prepolymers, a characteristic not previously suspected or reported.
SCOTS PINE REGENERATION IN A NEW FOREST INCLOSURE (1947)

SCOTS PINE REGENERATION IN A NEW FOREST INCLOSURE Get access E. W. JONES E. W. JONES Department of Forestry, University of Oxford Search for other works by this author on: Oxford Academic Google Scholar Forestry: An International Journal of Forest Research, Volume 21, Issue 2, 1947, Pages 151–178, https://doi.org/10.1093/oxfordjournals.forestry.a062878 Published: 01 October 1947
Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab (2014)

Our findings suggest that high tissue AMPK activation is a prognostic biomarker in this cohort of metastatic colorectal cancer patients.
Identifying Where to Focus in Reading Comprehension for Neural Question Generation (2017)

A first step in the task of automatically generating questions for testing reading comprehension is to identify questionworthy sentences, i.e. sentences in a text passage that humans find it worthwhile to ask questions about. We propose a hierarchical neural sentence-level sequence tagging model for this task, which existing approaches to question generation have ignored. The approach is fully data-driven -with no sophisticated NLP pipelines or any hand-crafted rules/features -and compares favorably to a number of baselines when evaluated on the SQuAD data set. When incorporated into an existing neural question generation system, the resulting end-to-end system achieves stateof-the-art performance for paragraph-level question generation for reading comprehension.
Fabrication of (Bi2Te3)0.25(Sb2Te3)0.75 Thermoelectric Film by Radio Frequency Sputtering Target Prepared by MA-PCS Process. (2002)

A p-type thermoelectric film of (Bi2Te3)0.25(Sb2Te3)0.75 was fabricated by radio frequency sputtering. The target for the sputtering was prepared by mechanical alloying (MA) and pulsed current sintering (PCS) process. The single phase of Bi0.5Sb1.5Te3 was obtained by planetary ball milling Bi powder, Te powder and Sb powder for 36ks. The obtained powder was consolidated by PCS into the cylindrical target of 50 mm in diameter and 4mm in thickness at 643 K under a pressure of 13 MPa. The sintered body consisted of Bi0.5Sb1.5Te3 without cracks. The sintered Bi0.5Sb1.5Te3 was joined to Cu backing plate with In for an insertion by PCS process. The thin film of (Bi2Te3)0.25(Sb2Te3)0.75 was fabricated on a polyimide substrate by RF sputtering. The thickness of this thin film was about 15-20μm. This film was amorphous state and crystallized at about 520 K. The performance of this p-type thermoelectric film after the crystallization were 2.0mV in voltage and 2.9μA in current at 20 K of the difference between heating side temperature 353 K and cooling side temperature 333 K.
ANALYTICAL PROCEDURES FOR CHARACTERIZING UNREGULATED EMISSIONS FROM VEHICLES USING MIDDLE-DISTILLATE FUELS (1980)

This research program was initiated with the objective of developing, codifying and testing a group of chemical analytical methods for measuring toxic compounds in the exhaust of distillate-fueled engines (i.e. diesel, gas turbine, Stirling, or Rankin cycle powerplants). It is a part of a larger effort to characterize these components from a number of prototype powerplants and, thus, represents a logical first step in the process. Methods of collection and analysis for aldehydes and ketones, for hydrogen cyanide and cyanogen, for hydrogen sulfide, carbonyl sulfide and organic sulfides, for ammonia and amines, for nitrous oxide, sulfur dioxide, individual hydrocarbons, for soluble sulfate and N-nitrosodimethylamine, benzo-a-pyrene, and phenols were studied in detail. Ten analytical procedures were developed and codified. Interference studies and proof-tests in diesel engine exhaust were conducted with every procedure and the results of these experiments are reported in detail.
Regression of experimental cancer by oral administration of combined α‐tocopherol and β‐carotene (1989)

alpha-Tocopherol (vitamin E) and beta-carotene have been shown to be capable of regressing established epidermoid carcinomas of hamster buccal pouch when injected locally into the tumor site. Neither has yet been shown to be effective in regressing cancer when administered by oral route. However, a combination of both alpha-tocopherol and beta-carotene was shown to be effective in regressing epidermoid carcinomas of hamster buccal pouch when the mixture was administered orally in vegetable oil. The epidermoid carcinomas were induced in the right buccal pouch of 100 Syrian hamsters by painting three times weekly for 14 weeks with a 0.5% solution of 7,12-dimethylbenz[a]anthracene in mineral oil. The animals were then divided into five equal groups of 20 animals. Group 1 animals received no further treatment and represented tumor controls. Group 2 animals received 200 micrograms beta-carotene and 200 micrograms dl-alpha-tocopherol acid succinate combined in 0.2 ml vegetable oil. Animals received the mixture daily by mouth using a 1-ml syringe. Groups 3 and 4 received beta-carotene and alpha-tocopherol individually in double amounts (400 micrograms in 0.2 ml vegetable oil). Group 5 animals received only the vegetable oil (0.2 ml daily) and were controls for vehicle. The animals in Groups 1, 3, 4, and 5 were killed after 22 weeks because the tumors were extensive, large, and necrotic and the animals were weak and cachectic. After 22 weeks, the tumors in Group 2 animals were small in 15 out of 20 animals. The tumors were reduced in size compared with tumor burden at 14 weeks, the point at which the beta-carotene/alpha-tocopherol was started.
Coherent optical ultrasound detection with rare-earth ion dopants (2010)

We describe theoretical and experimental demonstration for optical detection of ultrasound using a spectral hole engraved in cryogenically cooled rare-earth ion-doped solids. Our method utilizes the dispersion effects due to the spectral hole to perform phase-to-amplitude modulation conversion. Like previous approaches using spectral holes, it has the advantage of detection with large étendue. The method also has the benefit that high sensitivity can be obtained with moderate absorption contrast for the spectral holes.
Identifying, Quantifying, Extracting and Enhancing Implicit Parallelism (2009)

The shift of the microprocessor industry towards multicore architectures has\nplaced a huge burden on the programmers by requiring explicit parallelization\nfor performance. Implicit Parallelization is an alternative that could ease the\nburden on programmers by parallelizing applications ???under the covers??? while\nmaintaining sequential semantics externally. This thesis develops a novel\napproach for thinking about parallelism, by casting the problem of\nparallelization in terms of instruction criticality. Using this approach,\nparallelism in a program region is readily identified when certain conditions\nabout fetch-criticality are satisfied by the region. The thesis formalizes this\napproach by developing a criticality-driven model of task-based\nparallelization. The model can accurately predict the parallelism that would be\nexposed by potential task choices by capturing a wide set of sources of\nparallelism as well as costs to parallelization.\n\n\nThe criticality-driven model enables the development of two key components for\nImplicit Parallelization: a task selection policy, and a bottleneck analysis\ntool. The task selection policy can partition a single-threaded program into\ntasks that will profitably execute concurrently on a multicore architecture in\nspite of the costs associated with enforcing data-dependences and with\ntask-related actions. The bottleneck analysis tool gives feedback to the\nprogrammers about data-dependences that limit parallelism. In particular, there\nare several ???accidental dependences??? that can be easily removed with large\nimprovements in parallelism. These tools combine into a systematic methodology\nfor performance tuning in Implicit Parallelization. Finally, armed with the\ncriticality-driven model, the thesis revisits several architectural design\ndecisions, and finds several encouraging ways forward to increase the scope of\nImplicit Parallelization.
QueReSeek: Community-Based Web Navigation by Reverse Lookup of Search History (2008)

In this paper, we propose a system called QueReSeek that realizes Web navigation by using search queries in a community. Web navigation is realized as follows: when a user browsing some Web content, if the Web content is included in the list of results of past search by people in the community, query strings used in the search are shown to the user. To realize this navigation, the system collects queries to search engines and their results, and builds the search query-URL index. It shows relevant queries from the URL of Web content which is browsed by users based on this index. By looking up this database reversely, it can show related query strings to Web contents. Since the search queries in the community are keywords related to information and knowledge of interest within the community, this navigation reflects implicit knowledge in the community. It is useful especially for community members who are not proficient in search. Such users can learn search expertise by following search strings provided by the system. We implemented this proposed method in two ways. We could display relevant queries for approximately 20% of the browsed Web content in this experiment.
Pyramid Bumps for Fine-Pitch Chip-Stack Interconnection (2005)

We propose pyramid bumps as one of the compliant bumps for realizing stacked chips with fine-pitch chip interconnections. The pyramid bumps, made of Au, are fabricated by the bump transfer method. The bump size is approximately 13 µm at the base and pitch is 20 µm. A comparative study between the pyramid bump and the conventional plated bump is carried out. It is demonstrated that the pyramid bump deforms more easily than the plated bump. This indicates that the pyramid bump has a significant advantage over the plated bump in compensating the bump height deviation and the nonuniformity in bonding pressure and that the bonding of a pyramid bump can be achieved at smaller pressing loads than those necessary for a plated bump. It is also found that the pyramid bump effectively excludes insulating resin, which is precoated on the chip surface, from the bonding interface and thereby suppresses bonding failure.
A computational approach to measuring the correlation between expertise and social media influence for celebrities on microblogs (2014)

Existing approaches of social influence analysis usually focus on how to develop effective algorithms to quantize users' influence scores. They rarely consider a person's expertise levels which are arguably important to influence measures. In this paper, we propose a computational approach to measuring the correlation between expertise and social media influence, and we take a new perspective to understand social media influence by incorporating expertise into influence analysis. We carefully constructed a large dataset of 13,684 Chinese celebrities from Weibo (literally Sina microblogging). We found that there is a strong correlation between expertise levels and social media influence scores. In addition, different expertise levels showed influence variation patterns: high-expertise celebrities have stronger influence on the audience in their expertise domains.
Sparse Overcomplete Latent Variable Decomposition of Counts Data (2007)

An important problem in many fields is the analysis of counts data to extract meaningful latent components. Methods like Probabilistic Latent Semantic Analysis (PLSA) and Latent Dirichlet Allocation (LDA) have been proposed for this purpose. However, they are limited in the number of components they can extract and lack an explicit provision to control the expressiveness of the extracted components. In this paper, we present a learning formulation to address these limitations by employing the notion of sparsity. We start with the PLSA framework and use an entropic prior in a maximum a posteriori formulation to enforce sparsity. We show that this allows the extraction of overcomplete sets of latent components which better characterize the data. We present experimental evidence of the utility of such representations.
Point-source representation for laser-generated ultrasound (1984)

The stress-free thermal strain corresponding to the temperature rise induced in a target by an incident laser pulse constitutes a volume source of ultrasound. In the present work, the appropriate point-source representation is derived by starting from a general representation theorem for volume sources. A formal solution for the double (Hankel–Laplace) transform of the displacement potentials is obtained for axially symmetric configurations, with the point-source lying within or on the surface of a half-space or a plate. The Cagniard-de Hoop technique is used to invert these double transforms. For the source on the surface of a half-space, detailed results are presented for the wave-front expansions, the displacement along the axis of symmetry and on the surface, the directivity pattern, and the partition of energy between longitudinal, transverse, and surface waves. For the source within or on the surface of a plate, only the epicentral displacement is considered in detail.
Software Methodologies for the Engineering of Service-Oriented Industrial Automation: The Continuum Project (2009)

Service-orientation represents a new wave of features and solutions by bringing closer information technology to the industrial domain, particularly factory shop floors. The service-oriented automation software entities (designated here by bots) used in such approach requires a short set of methodologies and software targeting their specification for both computer systems and embedded automation devices. The present work explains the adopted methodologies and software developments for the engineering of service-based automation systems. The main contents focus on the specification of a framework for the development of bots and supporting engineering tools that are part of the Continuum project. The paper also does an overview over the engineering steps from the system design to the operation, and focuses the importance of the maintenance of automation bots. Such applications will contribute to decrease the development time and reduce the components' interdependency, offering enough flexibility for automatic reconfiguration of shop-floor layouts.
FEASIBILITY OF LIGHTWEIGHT CELLULAR CONCRETE FOR VEHICLE CRASH CUSHIONS (1970)

THREE VEHICLE CRASH TESTS OF LIGHTWEIGHT CELLULAR CONCRETE CRASH CUSHIONS ARE REPORTED, ALONG WITH PROPOSED PROCEDURES FOR CAST-IN-PLACE AND PRECAST CONSTRUCTION OF THESE DEVICES. THIS CRASH CUSHION, COMPOSED OF VERMICULITE CONCRETE, LIGHTWEIGHT WELDED WIRE FABRIC, AND CYLINDRICAL CARDBOARD FORMS, IS DESIGNED TO PROTECT MOTORISTS FROM COLLISIONS WITH RIGID OBSTACLES LOCATED ALONG THE ROADWAY. THE CRASH CUSHION HAS PROVED CRASH-WORTHY UNDER HEAD-ON TEST CONDITIONS. /AUTHOR/
Intermolecular N-H...O Hydrogen Bonding Assisted by Resonance. II. Self Assembly of Hydrogen-Bonded Secondary Enaminones in Supramolecular Catemers (1998)

The crystal structures of 15 compounds containing the 2-en-3-amino-1-one heterodienic system and forming intermolecular N—H...O hydrogen bonds assisted by resonance (RAHB) are reported: (1) 3-phenylamino-2-cyclohexen-1-one; (2) 3-(4-methoxyphenylamino)-2-cyclohexen-1-one; (3) 3-(4-chlorophenylamino)-2-cyclohexen-1-one; (4) 3-(4-methoxyphenylamino)-2-methyl-2-cyclohexen-1-one; (5) 3-(4-methoxyphenylamino)-5-methyl-2-cyclohexen-1-one; (6) 3-isopropylamino-5,5-dimethyl-2-cyclohexen-1-one; (7) 3-phenylamino-5,5-dimethyl-2-cyclohexen-1-one; (8) 3-(3-methoxyphenylamino)-5,5-dimethyl-2-cyclohexen-1-one; (9) N , N -3-aza-pentane-1,5-bis[1-(3-oxo-5,5-dimethyl-1-cyclohexenyl)]; (10) 3-phenylamino-6,6-dimethyl-2-cyclohexen-1-one; (11) 3-(2-methoxyphenylamino)-6,6-dimethyl-2-cyclohexen-1-one; (12) 3-(3-chlorophenylamino)-6,6-dimethyl-2-cyclohexen-1-one; (13) 3-(4-chlorophenylamino)-6,6-dimethyl-2-cyclohexen-1-one; (14) 1-(4-chlorophenyl)-4-(4-chlorophenylamino)-6-methyl-2-pyridone; (15) 3-(4-chlorophenylamino)-5-phenyl-2-cyclopenten-1,4-dione. All compounds form intermolecular N—H...O=C hydrogen bonds assisted by resonance connecting the heteroconjugated enaminonic groups in infinite chains. Chain morphologies are analyzed to find out crystal engineering rules able to predict and interpret the crystal packing. Simple secondary enaminones [ i.e. (1)–(13) together with a number of structures retrieved from the Cambridge Structural Database] are found to form hydrogen bonds having π-delocalizations, as characterized by a C=O bond-length average of 1.239 ± 0.004 Å, and hydrogen-bond strengths, represented by the N...O average distance of 2.86 ± 0.05 Å, very similar to those previously found for amides. Enaminones, however, can be easily substituted by chemical groups able to influence both π-conjugations and N...O hydrogen-bond distances. Some substituted enaminones, retrieved from the literature, display, in fact, N...O hydrogen-bond distances as short as 2.627 Å and large π-delocalizations with C=O double-bond distances as long as 1.285 Å. These effects appear to be associated with ( a ) the presence of further π-conjugated systems involving the C=O and NH groups of the enaminone moiety or ( b ) the transformation of the enaminone carbonyl group in an amidic function.
Ceftazidime-avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program (2016)

NCT01595438; NCT01599806.