gebhart/patrepeval huggingface dataset:
Channel Estimation for FDD Multi-User Massive MIMO: A Variational Bayesian Inference-Based Approach (2017)

This paper addresses downlink channel estimation for frequency division duplex multi-user massive multiple-input multiple-output systems. Suppose that a base station communicates with K mobile users, then the task is to estimate K channel matrices, each corresponding to one user. Due to the limited scattering in physical propagation, each channel matrix is sparse in the virtual angular domain. Besides, different user links tend to share some common scatterers. As such, different channel matrices may have a partially common sparsity pattern. These observations motivate us to take a variational Bayesian inference based approach for channel estimation. Specifically, we design a Gaussian mixture prior model, which can efficiently capture the individual sparsity in each channel matrix and the partially joint sparsity shared by different channel matrices. Furthermore, we develop a variational expectation maximization strategy to estimate the hyperparameters associated with the prior model and the channel matrices. Compared with the existing counterparts, the proposed approach achieves much better performance in terms of the channel estimation accuracy, while maintaining a low computational complexity.
Quality of Lyme Disease Tests (1989)

In this issue ofThe Journal, Schwartz and colleagues<sup>1</sup>report interlaboratory differences in serological test results for Lyme disease. Their findings confirm earlier results<sup>2</sup>and show that the rising number of tests performed in areas endemic for this disease can be very high. Lyme disease continues to receive major attention by the news media. Consequently, with the knowledge that the characteristic skin lesion erythema migrans may not always develop and that there is potential for long-term disorders that may be confused with other maladies, the public and the medical community have relied heavily on serum antibody tests for diagnosis. When patients are in the later stages of Lyme disease, marked by neurological or arthritic disorders, clinicians sometimes are faced with great difficulty in making a diagnosis. Like many other laboratory tests, assays for Lyme disease are less than perfect, and, as expressed by Schwartz et al,<sup>1</sup>some
Real-time urban traffic monitoring with global positioning system-equipped vehicles (2010)

Real-time traffic conditions are useful information based on which many adaptive traffic solutions work. In this study, the authors present a new approach for real-timely monitoring urban traffic with global positioning system (GPS)-equipped vehicles, which provides estimation of urban traffic conditions in real time. The approach first real-timely collects GPS trace data from GPS-equipped vehicles on the urban road network. Then, it periodically clusters the collected data of several minutes, calculates estimated space mean speed (eSMS) and translates eSMS to smooth indexes (denoting traffic conditions). Compared with existing work, the presented one: (i) applies an effective map matching method to cluster GPS trace data; (ii) excludes traffic signal's misleading influences on traffic condition estimation and (iii) judges traffic conditions based on an estimated critical traffic flow characteristic. Some experiments based on GPS taxi scheduling data of Shanghai, China are provided to demonstrate performance of this work.
Grating lobe minimization in sum and difference beam patterns (2004)

Subarray beam forming is widely employed in order to reduce hardware cost and system complexity. There is, of course, degradation in array performance due to correlated errors at the subarray level. The paper develops a new technique for the mitigation of quantization grating lobes, which may occur in a sum (/spl Sigma/) and difference (/spl Delta/) antenna beam pattern due to quantization of the aperture distribution at the subarray level.
Anti‐leukemic and anti‐angiogenic effects of <scp>d</scp>‐Limonene on K562‐implanted C57<scp>BL</scp>/6 mice and the chick chorioallantoic membrane model (2018)

These studies suggest promising anti-leukemic and anti-angiogenic effects of d-Limonene in the treatment of CML.
A 1-V 50-MHz Pseudodifferential OTA With Compensation of the Mobility Reduction (2007)

This brief presents a high-linearity operational transconductance amplifier (OTA) based on pseudodifferential structures. The linearity is improved by mobility compensation techniques as the device size is scaled down to achieve high speed operation. Transconductance tuning could be achieved by a MOS operating in the linear region. The OTA fabricated in the 0.18-mum CMOS process occupies a small area of 4.5 x 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> . The measured third-order intermodulation (IM3) distortion with a 400 mV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">PP</sub> differential input under 1-V power supply voltage remains below -52 dB for frequency up to 50 MHz. The static power consumption is 2.5 mW. Experimental results demonstrate the agreement with theoretical analyses.
9-Acridinyl and 2-methoxy-6-chloro-9-acridinyl derivatives of aliphatic di-, tri-, and tetraamines. Chemistry, cytostatic activity, and schistosomicidal activity (1983)

9-acridinyl derivatives of 1,6-hexanediamine, 1,8-octanediamine, bis(3-aminopropyl)amine, N,N'-bis(3-amino-propyl)piperazine, and N-ethyl-1,6-hexanediamine in the form of their hydrochlorides were prepared in high yields and converted into potential hetero bis DNA intercalating diacridines. The corresponding potential homo bis DNA intercalating reagents were prepared by heating the above amines with 9-chloroacridines. The chemical stability of the acridines was examined. Their cytostatic activity against Cloudman melanoma cells, in vitro, has been determined. The strongest cytostatic activity was observed for the acridine derivatives of the tri- and tetraamines. The schistosomicidal activity of selected acridine and diacridine derivatives against Schistosoma mansoni in mice was found to be insignificant. The S. mansoni egg development was apparently suppressed by this treatment.
The Action of Hydrochloric Acid upon Cultures of<i>Trichomonas</i> (1930)

The question of the mode of transmission of the Trichomonas of man from one host to another is of particular interest because no authentic encysted stage is known. Many workers have attempted to infect “clean” animals by the mouth with active trichomonads from a variety of hosts, either from cultures or directly from faeces. The results are conflicting. Thus Escomel (1913) fed faeces containing Trichomonas intestinalis ( = T. hominis ) from a human case of dysentery to a rabbit, a guinea-pig, a cat, and a dog, and obtained a positive result in the dog. He does not, however, state that he examined his animals, to find whether they had any similar natural infections, before performing his experiments. Boyd (1919) fed a culture of Trichomonas intestinalis ( = T. hominis ), mixed with milk, to a white rat and infected it. He had previously examined this rat and one used as a control and found them to be free from this flagellate. He was, himself, uncertain whether the infection was due to the free flagellates or their “cysts“ which he says were present in the culture. The cysts figured by him (Plate XI, figs. 7–17) appear to be rounded-up and degenerating trichomonads. Pringault (1920) fed Trichomonas intestinalis ( = T. hominis ) to a cat, a guinea-pig, a rabbit, and a white rat, without establishing an infection in any one of them.
Parallel Error Detection Using Heterogeneous Cores (2018)

Microprocessor error detection is increasingly important, as the number of transistors in modern systems heightens their vulnerability. In addition, many modern workloads in domains such as the automotive and health industries are increasingly error intolerant, due to strict safety standards. However, current detection techniques require duplication of all hardware structures, causing a considerable increase in power consumption and chip area. Solutions in the literature involve running the code multiple times on the same hardware, which reduces performance significantly and cannot capture all errors. We have designed a novel hardware-only solution for error detection, that exploits parallelism in checking code which may not exist in the original execution. We pair a high-performance out-of-order core with a set of small low-power cores, each of which checks a portion of the out-of-order core's execution. Our system enables the detection of both hard and soft errors, with low area, power and performance overheads.
Upgrading Outdated Rectifier Control Systems - Needs and Challenges (2006)

Rectifier control systems supplied in the 1970's and 80's were based upon analog technology. These systems typically have failures which result in longer down times since components are either not available, are obsolete or need to be repaired. Tolerance degradation of these components contributes to problems such as loss of regulation accuracy or the malfunctioning gate firing circuits leading to potentially heavy production losses. This makes it difficult to run the plant economically and is unsafe for operating people. Modern control systems are quite comprehensive, which poses a great challenge when considering an upgrade for old control systems. An upgrade must result in more reliable and efficient operation. Time available for designing, manufacturing and execution is typically very short. Necessary logic, interlocks, etc. to match current operation philosophy has to be achieved. When conventional maintenance procedures are not adequate to improve the availability, safety, productivity and efficiency of a plant beyond a certain level, then a technical assessment of the plant needs to be carried out to determine ways for upgrade or replacement. This paper presents a case study for control replacements for a thyristor plant and for a diode plant, illustrating needs and challenges, including: incorporating centralized control; improvement in measurement accuracy to increase production; monitoring and recording of important parameters such as current, flows, temperatures, etc.; high speed response capabilities to protect the system; suitable firing circuitry for thyristor plants; event recording, listing and printing all events that occurred, hence providing a fault diagnostics tool; elimination of possible human errors in operation and maintenance; high immunity against electro magnetic noise; and suitability for existing plant topology
Purification and Some Physicochemical Properties of Enterotoxin C, Staphylococcus aureus Strain 361<sup>*</sup> (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPurification and Some Physicochemical Properties of Enterotoxin C, Staphylococcus aureus Strain 361*Remedios M. Avena and Merlin S. BergdollCite this: Biochemistry 1967, 6, 5, 1474–1480Publication Date (Print):May 1, 1967Publication History Published online1 May 2002Published inissue 1 May 1967https://pubs.acs.org/doi/10.1021/bi00857a033https://doi.org/10.1021/bi00857a033research-articleACS PublicationsRequest reuse permissionsArticle Views98Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis and optical properties of S-doped ZnO nanowires (2003)

S-doped ZnO nanowires with an average diameter of 80 nm and length up to several tens of micrometers were produced through a simple physical evaporation approach. The nanowires had a single-crystal hexagonal structure and grew along the [102] direction. Photoluminescence (PL) measurements showed that the doping of sulfur shifted the PL spectrum peak towards short wavelengths, and the doping quantity was found responsible for the different characteristics.
An RCP Packaged Transceiver Chipset for Automotive LRR and SRR Systems in SiGe BiCMOS Technology (2012)

We present a transceiver chipset consisting of a four channel receiver (Rx) and a single-channel transmitter (Tx) designed in a 200-GHz SiGe BiCMOS technology. Each Rx channel has a conversion gain of 19 dB with a typical single sideband noise figure of 10 dB at 1-MHz offset. The Tx includes two exclusively-enabled voltage-controlled oscillators on the same die to switch between two bands at 76-77 and 77-81 GHz. The phase noise is -97 dBc/Hz at 1-MHz offset. On-wafer, the output power is 2 × 13 dBm. At 3.3-V supply, the Rx chip draws 240 mA, while the Tx draws 530 mA. The power dissipation for the complete chipset is 2.5 W. The two chips are used as vehicles for a 77-GHz package test. The chips are packaged using the redistribution chip package technology. We compare on-wafer measurements with on-board results. The loss at the RF port due to the transition in the package results to be less than 1 dB at 77 GHz. The results demonstrate an excellent potential of the presented millimeter-wave package concept for millimeter-wave applications.
CMOS current reference with supply and temperature compensation (2007)

The dependency of CMOS current reference on supply voltage and temperature is compensated by simply subtracting two current outputs with the same dependencies on the supply voltage and temperature. With this compensation scheme, a self-biased CMOS current reference has been implemented in a 0.25 µm standard CMOS technology. The current reference provides 10.45 µA output current, while the supply and temperature dependencies are 1700 ppm/V and 720 ppm/°C, respectively. The current reference occupies only 0.002 mm2 active area and can operate down to 1.1 V.
Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest (2006)

A mechanism of increased cell death by genistein and radiation is proposed to occur via inhibition of NF-kappaB, leading to altered expression of regulatory cell cycle proteins such as cyclin B and/or p21WAF1/Cip1, thus promoting G2/M arrest and increased radiosensitivity. These findings support the important and novel strategy of combining genistein with radiation for the treatment of prostate cancer.
Bone-targeted agents in the treatment of lung cancer (2015)

Over a third of patients with lung cancer will develop bone metastases during the course of their disease, resulting in symptoms of pain and immobility, and skeletal-related events (SREs) such as fracture, hypercalcaemia, surgery or radiotherapy to bones, and malignant spinal cord compression. These reduce quality of life and increase mortality. Preclinical research has identified the interactions between tumour cells and bone that are key to tumour cell survival and associated osteolysis. These data have led to the development of drugs to prevent osteoclast-mediated bone breakdown, such as zoledronic acid and denosumab, which are now licensed for use in patients with bone metastases from solid tumours. Both zoledronic acid and denosumab reduce the risk of SREs and increase time to first SRE, with minimal side effects. In addition, denosumab improved survival in patients with lung cancer compared with zoledronic acid. Ongoing trials are testing whether these drugs can prevent the development of bone metastases from lung cancer. New bone-targeted agents showing promise in breast and prostate cancer include radium-223, cabozantinib and Src inhibitors. These agents require further evaluation in patients with lung cancer.
Acoustic Sensing for Soft Pneumatic Actuators (2018)

We propose a novel sensing method for soft pneumatic actuators. The method uses a single microphone, embedded into the actuator's air chamber. Contact with the environment induces sound (vibration) in the actuator. The materials and the shape of the actuator reflect, refract, and attenuate the sound as it propagates inside the actuator. This produces a unique sound signature for different types of events, enabling the sensing of contact locations, contact force, and the type of contacted material. Sensing is insensitive to the inflation state of the actuator and to background noise. We demonstrate the robustness and versatility of the microphone-based sensor solution in experiments with a PneuFlex actuator. The proposed sensorization avoids the fundamental challenges of sensorizing soft pneumatic actuators, because the placement of a microphone does not negatively affect the compliance of the actuator and because a single microphone suffices for sensorization of the entire actuator, eliminating the need for an application-specific sensor layout.
Systematic design of phase-shifting masks with extended depth of focus and/or shifted focus plane (1992)

We propose an optimization based algorithm for designing phase-shifting masks. Our approach is an extension of our previous work [1, 2, 3] in the sense that the intensity image is optimized at a number of optical planes rather than just the focus plane. In addition, our algorithm can be used to design masks with shifted focus plane and/or extended depth of focus. We also propose the concept of “dual mask” and show its consequences to practical phase-shifting mask design. Finally, we show examples of our proposed design techniques for single line phase connectors, cross phase connectors, contact holes and bright lines. Simulation and experimental results verify the capability of our design technique to extend depth of focus and shift the focus plane.
Phase 1 study of the MDM2 antagonist RO6839921 in patients with acute myeloid leukemia (2020)

In acute myeloid leukemia (AML), TP53 mutations and dysregulation of wild-type p53 is common and supports an MDM2 antagonist as a therapy. RO6839921 is an inactive pegylated prodrug of the oral MDM2 antagonist idasanutlin (active principle [AP]) that allows for IV administration. This phase 1 monotherapy study evaluated the safety, pharmacokinetics, and pharmacodynamics of RO6839921 in patients with AML. Primary objectives identified dose-limiting toxicities (DLTs) and maximum tolerated dose (MTD). Secondary objectives assessed pharmacokinetic, pharmacodynamic, and antileukemic activity. A total of 26 patients received 120-300 mg AP of idasanutlin. The MTD was 200 mg, with DLTs at 250 (2/8 patients) and 300 mg (2/5). Treatment-related adverse events in >20% of patients were diarrhea, nausea, vomiting, decreased appetite, and fatigue. Six deaths (23.1%) occurred, all unrelated to treatment. Pharmacokinetics showed rapid and near-complete conversion of the prodrug to AP and dose-proportional exposure across doses. Variability ranged from 30%-47% (22%-54% for idasanutlin). TP53 was 21 (87.5%) wild-type and 3 mutant (12.5%). The composite response rate (complete remission [CR], CR with incomplete hematologic recovery/morphological leukemia-free state [CRi/MLFS], or CR without platelet recovery [CRp]) was 7.7%. Antileukemic activity (CR, CRi/MLFS, partial response, hematologic improvement/stable disease) was observed in 11 patients (disease control rate, 42%): 10/11 were TP53 wild-type; 1 had no sample. p53 activation was demonstrated by MIC-1 induction and was associated with AP exposure. There was not sufficient differentiation or improvement in the biologic or safety profile compared with oral idasanutlin to support continued development of RO6839921. NCT02098967.
Definitions and Principles (1990)

The subject of this book is theatre created specifically with young audiences in mind, for the most part in Great Britain but with some comparative references to what has gone on and what is going on in the United States of America and in East Germany. For practical reasons, it will be limited to theatre which expresses itself in plays and plays performed by human actors, and it will not attempt to encompass and thereby possibly do scant justice to puppetry and dance. It will also concentrate on plays produced by professional or amateur companies. This is in no way to undervalue the work of Youth Theatres. Youth Theatre is defined by the Standing Conference of Young People’s Theatre (SCYPT) as ‘theatre done by young people themselves, usually led by a teacher or under the auspices of a Young People’s Company’. I acknowledge the fact that such work can sometimes issue in an artistic statement of high quality but its value resides at least partly in the benefit it affords to the participants and, in the last analysis, this takes priority. It is exclusively with theatre for young people as an art form and as practised by adults that the book will deal.
Osteogenic differentiation of human umbilical cord- derived mesenchymal stem cells promoted by overexpression of osterix (2013)

Background: Umbilical cord-derived mesenchymal stem cells (UC-MSCs) are considered to be multipotentmesenchymal stem cells that are easily induced to differentiate into functional osteoblasts both in vitro andin vivo. Osterix (Osx), a novel zinc-nger-containing transcription factor of the Sp family, is required for osteoblastdifferentiation and bone formation. Objective: We investigated the effect of Osx on the proliferation and osteogenic differentiation of the UC-MSCs. Method: The primary UC-MSCs were isolated and cultured. An Osx-expressing plasmid (pEGFP-Osx) wasconstructed and transfected into UC-MSCs. Then expression of bone morphogenesis-related genes, proliferationrate, alkaline phosphatase activity, and mineralization were examined to evaluate the osteogenic potential of theOsx gene-modified UC-MSCs. Result: UC-MSCs transfected with pEGFP-Osx exhibited apparent osteogenic differentiation as determined byincreased activity of alkaline phosphatase, the formation of mineralized nodules and the expression of relatedosteoblastic genes. Conclusion: These results conrmed the ability of Osx to enhance osteoblast differentiation of UC-MSCsin vitro, and the Osx gene-modified UC-MSCs are potential as novel cell resources of bone tissue engineering. Keywords: Osteogenic differentiation, osterix, umbilical cord-derived mesenchymal stem cells
Immiscible Displacements and Capillary Trapping in CO2 Storage (2011)

We measure the residual non-wetting phase saturation of super-critical carbon dioxide in a Berea sandstone core. We use the porous plate method while a stirred reactor ensures equilibrium between the carbon dioxide and brine. We also measure carbon dioxide-brine contact angles on the porous plate to understand wetting behavior in the experiment. The application of the work is for carbon dioxide storage in aquifers, where capillary trapping is a rapid and effective mechanism to render the injected fluid immobile. The experiment was performed at temperature and pressure representative of potential subsurface storage formations. The measured residual saturation is 37% which is lower than the measured residual for an oil-brine system on a similar core (48%), but higher than measured by other authors for super-critical CO2 in Berea sandstone. We suggest that super-critical CO2 is still non-wetting in sandstones with considerable trapping and discuss the implications for CO2 storage in aquifers.