gebhart/patrepeval huggingface dataset:
Heuristics for Thread-Level Speculation in Web Applications (2014)

JavaScript is a sequential programming language, and Thread-Level Speculation has been proposed to dynamically extract parallelism in order to take advantage of parallel hardware. In previous work, we have showed significant speed-ups with a simple on/off speculation heuristic. In this paper, we propose and evaluate three heuristics for dynamically adapt the speculation: a 2-bit heuristic, an exponential heuristic, and a combination of these two. Our results show that the combined heuristic is able to both increase the number of successful speculations and decrease the execution time for 15 popular web applications.
Combined Physiologic and Radiologic Studies of Bladder Function in Female Children with Recurrent Urinary Tract Infections (1967)

(Scanford University School of Medicine, Palo Alto. California) Yale University, School of Medicine, New Haven, Con
Motif-based Convolutional Neural Network on Graphs (2017)

This paper introduces a generalization of Convolutional Neural Networks (CNNs) to graphs with irregular linkage structures, especially heterogeneous graphs with typed nodes and schemas. We propose a novel spatial convolution operation to model the key properties of local connectivity and translation invariance, using high-order connection patterns or motifs. We develop a novel deep architecture Motif-CNN that employs an attention model to combine the features extracted from multiple patterns, thus effectively capturing high-order structural and feature information. Our experiments on semi-supervised node classification on real-world social networks and multiple representative heterogeneous graph datasets indicate significant gains of 6-21% over existing graph CNNs and other state-of-the-art techniques.
Origin of cholesterol in the fetal golden Syrian hamster: contribution of de novo sterol synthesis and maternal-derived lipoprotein cholesterol. (1996)

A fetal hamster increases in mass almost 100-fold in the third trimester of gestation. During this 5.5-day period, the acquisition of over 4 mg of cholesterol is required for normal development. The purpose of the present studies was to determine the potential source(s) of this fetal sterol. Rates of cholesterol synthesis in the whole fetus were measured initially. Synthesis rates in the whole fetus increased linearly from 10 days (approximately 25 nmol sterol/h) through 13.5 days of gestation (approximately 400 nmol sterol/h). During the last 1.5 days of intrauterine development, rates remained constant. Even though the synthesis rates were relatively elevated, as compared to those in an adult, the amount of cholesterol synthesized was about half of that accrued. When synthesis rates in all of the fetal tissues were summed, however, a majority of the sterol in the fetus could now be accounted for. During this same time when the fetus was accumulating 4 mg of cholesterol, the placenta and yolk sac increased in cholesterol content by 2.5 mg, indicating the need for a second source of sterol for fetal tissue development. Two other sources of sterol for these tissues were found to be maternal low density and high density lipoprotein (LDL and HDL, respectively). In fact, more than 0.9 mg of cholesterol was taken up during the third trimester as LDL. To summarize, a majority of cholesterol in the fetus could be accounted for by synthesis in all fetal tissues. Additionally, a significant amount of cholesterol was taken up as maternal-derived LDL and HDL by these same tissues.
A System for Graphical Interaction on Parametrized Models (1988)

A system that enables the definition of parametrized solid models by means of graphical interaction is presented. The position, orientation and dimensions of primitive volumes for Constructive Solid Geometry (CSG) are determined by a number of control points. All control points are linked to nodes in a tree of local coordinate systems. The relations between control points is therefore determined by the relations of the nodes in this geometric tree. The user can create nodes and define geometric relations between them by graphical interaction on the geometric tree. With the system described in this paper, it is possible to define relations
Higher-Order Spreadsheets with Spilled Arrays (2020)

Abstract We develop a theory for two recently-proposed spreadsheet mechanisms: gridlets allow for abstraction and reuse in spreadsheets, and build on spilled arrays , where an array value spills out of one cell into nearby cells. We present the first formal calculus of spreadsheets with spilled arrays. Since spilled arrays may collide, the semantics of spilling is an iterative process to determine which arrays spill successfully and which do not. Our first theorem is that this process converges deterministically. To model gridlets, we propose the grid calculus , a higher-order extension of our calculus of spilled arrays with primitives to treat spreadsheets as values. We define a semantics of gridlets as formulas in the grid calculus. Our second theorem shows the correctness of a remarkably direct encoding of the Abadi and Cardelli object calculus into the grid calculus. This result is the first rigorous analogy between spreadsheets and objects; it substantiates the intuition that gridlets are an object-oriented counterpart to functional programming extensions to spreadsheets, such as sheet-defined functions.
Design of Experiment for Optimization of Plasma-Polymerized Octafluorocyclobutane Coating on Very High Aspect Ratio Silicon Molds (2006)

As-fabricated deep reactive ion etched (DRIE) silicon mold with very high aspect ratio (>10) feature patterns is unsuitable for poly(dimethylsiloxane) (PDMS) replication because of the strong interaction between the Si surface and the replica and the corrugated mold sidewalls. The silicon mold can be conveniently passivated via plasma polymerization of octafluorocyclobutane (C4F8), which is also employed in the DRIE process itself, to enable the mold to be used repeatedly. To optimize the passivation conditions, we have undertaken a Box-Behnken experimental design on the basis of three passivation process parameters (plasma power, C4F8 flow rate, and deposition time). The measured responses were fluorinated film thickness, demolding status/success, demolding force, and fluorine/carbon ratio on the fifth replica surface. The optimal passivation process conditions were predicted to be an input power of 195 W, a C4F8 flow rate of 57 sccm, and a deposition time of 364 s; these were verified experimentally to have high accuracy. Demolding success requires medium-deposited film thickness (66-91 nm), and the thickness of the deposited films correlated strongly with deposition time. At moderate to high ranges, increased plasma power or gas flow rate promoted polymerization over reactive etching of the film. It was also found that small quantities of the fluorinated surface were transferred from the Si mold to the PDMS at each replication, entailing progressive wear of the fluorinated layer.
A Computer-Assisted Electrode System for Measuring Blood pH, pO2, pCO2, Sodium, and Potassium (1970)

Abstract An experimental automatic electrode system was constructed to determine the feasibility of making routine determinations of blood pH, pO2, pCO2, sodium, and potassium in intensive care units. The equipment standardizes itself automatically every 25 min, and is self-cleaning after a blood specimen has been analyzed. The analyzer is connected on-line to an IBM 1800 computer on an interrupt basis. There was no significant difference between the results for pH, pO2, and pCO2 obtained with this machine and those by manual methods. The precision obtainable for the five determinations is given. The relationship between blood and plasma sodium and potassium activities determined with the glass electrodes and plasma sodium and potassium concentrations determined by flame photometry is discussed.
Protein Tyrosine Phosphatase-1B Inhibitory Activity of Isoprenylated Flavonoids Isolated from <i>Erythrina </i><i>mildbraedii</i> (2006)

Inhibition of protein tyrosine phosphatase-1B (PTP1B) has been proposed as a therapy for treatment of type-2 diabetes and obesity. Bioassay-guided fractionation of an EtOAc-soluble extract of the root bark of Erythrina mildbraedii, using an in vitro PTP1B inhibitory assay, resulted in the isolation of three new isoprenylated flavonoids, abyssinone-IV-4'-O-methyl ether (2), 7-hydroxy-4'-methoxy-3'-(3-hydroxy-3-methyl-trans-but-1-enyl)-5'-(3-methylbut-2-enyl)flavanone (3), and abyssinone-VI-4-O-methyl ether (6), along with six known flavonoids, abyssinone-V-4'-O-methyl ether (1), abyssinone-V (4), abyssinone-IV (5), sigmoidin E (7), 4'-hydroxy-5,7-dimethoxyisoflavone (8), and alpinumisoflavone (9). Compounds 1 and 2, 4-7, and 9 inhibited PTP1B activity, with IC50 values ranging from 14.8 +/- 1.1 to 39.7 +/- 2.5 microM. On the basis of the data obtained, flavanones and chalcones with isoprenyl groups may be considered as a new class of PTP1B inhibitors.
Seizure Suppression by GDNF Gene Therapy in Animal Models of Epilepsy (2007)

Temporal lobe epilepsy patients remain refractory to available anti-epileptic drugs in 30% of cases, indicating a need for novel therapeutic strategies. In this context, glial cell line-derived neurotrophic factor (GDNF) emerges as a possible new agent for epilepsy treatment. However, a limited number of studies, use of different epilepsy models, and different methods of GDNF delivery preclude understanding of the mechanisms for the seizure-suppressant action of GDNF. Here we show that recombinant adeno-associated viral (rAAV) vector-based GDNF overexpression in the rat hippocampus suppresses seizures in two models of temporal lobe epilepsy. First, when rAAV-GDNF was injected before hippocampal kindling, the number of generalized seizures decreased, and the prolongation of behavioral convulsions in fully kindled animals was prevented. Second, injection of rAAV-GDNF after kindling increased the seizure induction threshold. Third, rAAV-GDNF decreased the frequency of generalized seizures during the self-sustained phase of status epilepticus. Our data demonstrate the complexity of mechanisms and the beneficial action of GDNF in epilepsy. Furthermore, we show that ectopic rAAV-mediated GDNF gene expression in the seizure focus is a feasible way to mitigate seizures and provides proof of principle that the neurotrophic factor-based gene therapy approach has the potential to be developed as alternative strategy for epilepsy treatment.
A Remark Concerning m-Divisibility and the Discrete Logarithm in the Divisor Class Group of Curves (1994)

The aim of this paper is to show that the computation of the discrete logarithm in the m-torsion part of the divisor class group of a curve X over a finite field ko (with char(ko) prime to m), or over a local field k with residue field ko, can be reduced to the computation of the discrete logarithm in k0(4m)* . For this purpose we use a variant of the (tame) Tate pairing for Abelian varieties over local fields. In the same way the problem to determine all linear combinations of a finite set of elements in the divisor class group of a curve over k or ko which are divisible by m is reduced to the computation of the discrete logarithm in ko(Cm)* -
New generation metro networks: Challenges and opportunities (2010)

There is need to investigate new technological directions to make the metro network more efficient at a lower cost. We have proposed a Packet-Optical Add/Drop Technology combining packet granularity and optical bypass to reach this objective. A system analysis shows that this new technology requires less transmitters/receivers than any other alternative technology, reducing the cost and the overall power consumption.
Pattern deformation induced from intensity-unbalanced off-axis illumination (1997)

Currently it is very popular to use off-axis illumination technique for higher resolution with wider depth of focus. However there are several problems in the technique, one of which is deterioration of image quality induced by the non- uniform effective source distribution. If the intensity distribution on the illumination aperture lacks of spatial symmetry, each diffraction order beam impinging on the wafer surface has angularly asymmetric distribution. This makes the optical system have pattern size dependent telecentricity error. For a simple line or grouped lines it gives rise to only the pattern displacement with defocus which can hardly be detected unless there are any reference. But the periodic island type patterns which have discrete features and multiple pitch components in one direction can be bent and deformed asymmetrically with defocus. Asymmetric imaging for island type patterns gives rise to also the pattern CD asymmetry with defocus. We present schematic explanation of the effects of non-uniform effective source and the simulation result. We also investigated the phenomena in a high density DRAM cell active layer of 460 nm minimum pitch and characterized it by various approach.
Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.). (1996)

Onion and garlic contain many sulfur containing active principles mainly in the form of cysteine derivatives, viz. S-alkyl cysteine sulfoxides which decompose into a variety of thiosulfinates and polysulfides by the action of an enzyme allinase on extraction. Decomposed products are volatile and present in the oils of onion and garlic. They possess antidiabetic, antibiotic, hypocholesterolaemic, fibrinolytic and various other biological actions. In addition to free sulfoxides in alliums, there are nonvolatile sulfur-containing peptides and proteins which possess various activities and thus make these vegetables as an important source of therapeutic agents. As allyl and related sulfoxides are inhibiting thiol group enzymes, alliums are to be used only in limited quantities.
Modeling of cross-regulation in converters containing coupled inductors (2002)

A general model of the multiple-winding coupled inductor is described, in which all parameters can be directly measured. This model is employed in a tutorial explanation of the mechanisms by which leakage inductances and effective turns ratios affect cross regulation and discontinuous conduction mode boundaries in a multiple-output converter. Three basic approaches to coupled-inductor design are compared: near-ideal coupling, practical moderate coupling, and the zero-ripple approach. Near-ideal coupling results in good cross-regulation even when some outputs become discontinuous; however, realization of near-ideal coupling may be difficult in practice, and the resulting circulating currents can also lead to increased output voltage ripples and reduced efficiency. The best cross regulation can be obtained via the zero-ripple approach with relatively loose coupling in applications where there is at least one output whose load current variations are relatively small so that all windings can always operate in the continuous conduction mode. The conclusions are supported by experimental results.
Imaging correlations of tau, amyloid, metabolism, and atrophy in typical and atypical Alzheimer's disease (2018)

These findings support a close relationship between tau and hypometabolism in Alzheimer's disease but show that correlations between neuroimaging modalities vary across participants.
Boar Taint is Related to Endocrine and Anatomical Changes at Puberty but not to Aggressive Behaviour in Entire Male Pigs (2005)

This study aimed to describe the association between incidence of boar taint and pubertal changes in gonadal hormones, size of reproductive organs and aggressive behaviour in entire male pigs. In total, 111 entire male pigs were included in the study. Sampling was performed first at 90 kg live weight (LW) and, then, at 115 kg LW. Variables measured were skatole and androstenone levels in plasma and fat, testosterone and oestrone sulphate in plasma, free oestrone in fat, weight of testes and length of bulbourethral glands. Aggressive interactions between pigs were registered when a limited amount of feed was provided to the pigs prior to routine feeding. The number of initiated interactions (attacks) and the difference between number of initiated and received interactions (relative attacks) were calculated for each pig. Multivariate analysis revealed that gonadal hormones and reproductive organ size influenced prevalence of boar taint, accounting for 30% of the variation in skatole levels in fat and for 37% of the variation in androstenone levels in fat. These relations were independent of aggression levels in entire male pigs. Skatole levels were influenced by the levels of oestrone sulphate in plasma and free oestrone in fat, but not levels of plasma testosterone. Pigs with testes weight below 565 g and a bulbourethral gland length <90 mm did not produce high amounts of skatole; therefore, these values can be used as a threshold level to detect pig carcasses with low skatole levels. High androstenone levels could not be predicted by measuring reproductive organ sizes. More research is required to develop a rapid and accurate method for the analysis of carcasses of entire male pigs.
Non-Viral Gene Delivery with Cationic Liposome–DNA Complexes (2008)

A large amount of research activity worldwide is currently directed towards developing lipid- or polymer-based, non-viral gene vectors for therapeutic applications. This strong interest is motivated by their low toxicity, ease of production, ability to transfer large pieces of DNA into cells, and lack of immunogenic protein components. Cationic liposomes (CLs) are one of the most powerful non-viral vectors. In fact, CL-based vectors are among the prevalent synthetic carriers of nucleic acids currently used in human clinical gene therapy trials as well as in cell transfection applications for biological research. Our understanding of the mechanisms of action of CL-DNA complexes is still in its infancy. However, the relevance of a few crucial parameters, such as the lipid/DNA charge ratio (rho(chg)) and the membrane charge density of lamellar complexes (sigma(M)), is well established. To arrive at true comparisons of lipid performance, one must optimize both these parameters using a reproducible, reliable transfection assay. In this chapter, we aim to provide the reader with detailed procedures for liposome formation and transfection. It is our hope that the use of such optimized protocols will improve the comparability of transfection data obtained with novel lipids.
Synthesis of 2,2-disubstituted 7-methylenenorbornanes with 2-exo functionality by Diels-Alder reaction of 5,5-dimethoxytetrachlorocyclopentadiene (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 2,2-disubstituted 7-methylenenorbornanes with 2-exo functionality by Diels-Alder reaction of 5,5-dimethoxytetrachlorocyclopentadieneHugh W. Thompson, Jesse K. Wong, Roger A. Lalancette, Jean A. Boyko, and Anthony M. RobertielloCite this: J. Org. Chem. 1985, 50, 12, 2115–2121Publication Date (Print):June 1, 1985Publication History Published online1 May 2002Published inissue 1 June 1985https://pubs.acs.org/doi/10.1021/jo00212a022https://doi.org/10.1021/jo00212a022research-articleACS PublicationsRequest reuse permissionsArticle Views255Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADEM: Automating deployment and management of application software on the Open Science Grid (2009)

In grid environments, the deployment and management of application software presents a major practical challenge for end users. Performing these tasks manually is error-prone and not scalable to large grids. In this work, we propose an automation tool, ADEM, for grid application software deployment and management, and demonstrate and evaluate the tool on the Open Science Grid. ADEM uses Globus for basic grid services, and integrates the grid software installer Pacman. It supports both centralized ¿prebuild¿ and on-site ¿dynamic-build¿ approaches to software compilation, using the NMI Build and Test system to perform central prebuilds for specific target platforms. ADEM's parallel workflow automatically determines available grid sites and their platform ¿signatures¿, checks for and integrates dependencies, and performs software build, installation, and testing. ADEM's tracking log of build and installation activities is helpful for troubleshooting potential exceptions. Experimental results on the Open Science Grid show that ADEM is easy to use and more productive for users than manual operation.
Microwave-bandwidth optical receiver systems (1967)

A theoretical and experimental evaluation of optical communications systems capable of microwave bandwidths is presented. The optical transmitter, modulator, and detection techniques are discussed with respect to both direct-detection and optical heterodyne receivers, and experiments in a nonlaboratory environment are described. At the high optical power levels or photon rates which are fundamentally necessary for gigahertz instantaneous bandwidths, it is found that signal-shot-noise limited operation may be obtained with new wideband photodetectors incorporating internal gain. Direct-detection receivers are thus generally superior to heterodyne receivers in these systems. A comparison is made of the relative merits of alternative systems and their dependence on various parameters such as information capacity, range, and background illumination.
2,2′‐Binaphthyliden‐1,1′ ‐dione – Farbe und Struktur (1991)

2,2′‐Binaphthylidene‐1,1′ ‐diones – Colour and Structure The UV spectra of deep purple to green 2,2′‐binaphthylen‐1,1′‐diones 3 may be explained by substituent increments with high reliability. This allows assistence in structure elucidation of substituted 1‐naphtholes 1a by UV/Vis measurements of their oxidation products, or colour adjustment of 3 for use in diagnostic purposes. Also highly soluble derivatives of 3 were synthesized for the first time.
Dynamics of Damage in Two-Dimensional Structures With Waiting Links (2006)

The paper deals with simulation of damage spread in special structures with “waiting links.” These structures are stable against dynamic impacts due to their morphology. They are able to transform “partial damage” through a large region, thereby dissipating the energy of the impact. We simulate various structures with waiting links and compare their characteristics with conventional designs.
SCHWEISSEN UND LOETEN VON ALUMINIUMWERKSTOFFEN (1977)

NACH EINER BESPRECHUNG DES ALUMINIUMS UND DER ALUMINIUMWERKSTOFFE WERDEN DIE SCHWEISSVERFAHREN, WIE SCHMELZSCHWEISSEN UND PRESSSCHWEISSEN, DIE LOETVERFAHREN UND DIE THERMISCHEN SCHNEIDVERFAHREN DARGESTELLT. VOR- UND NACHBEHANDLUNG DER SCHWEISSKONSTRUKTIONEN, SCHWEISSFEHLER UND DAS PRUEFEN VON SCHWEISSVERBINDUNGEN. DIE FESTIGKEITEN UND EIGENSCHAFTEN VON SCHWEISSVERBINDUNGEN, DEREN WERKSTOFFGERECHTE GESTALTUNG UND ANWENDUNGSBEISPIELE. VORSCHRIFTEN, NORMEN, RICHTLINIEN UND MERKBLAETTER. (A*)