gebhart/patrepeval huggingface dataset:
A Feature Representation Method of Social Graph for Malware Detection (2013)

The proliferation of malware has presented a serious threat to internet security, and made traditional signature-based methods unable to analyze and process the massive data timely and effectively. The development trend of malware motivates many research efforts in intelligent malware analysis, where machine learning is used for malware detection. Currently, most of machine learning methods on malware detection utilize file contents extracted from the file samples. However, besides file contents, relations among file samples can provide invaluable information about the properties of file samples, which may improve the malware detection accuracy. Social graph is a popular way to present a set of socially-relevant nodes connected by one or more relations. It can well present the relations/dependence among file samples. Therefore, we attempt to employ social graph to study the file relations as the feature representation of file samples, and combine machine learning methods to detect malware.
Learning the Writing Process in Teacher Education Classes (1992)

(1992). Learning the Writing Process in Teacher Education Classes. Action in Teacher Education: Vol. 14, No. 2, pp. 60-64.
Revisión metodológica de la tradicional tesis de nuestra historiografía sobre la denominada conspiración masónica del sexenio negro (1992)

Altogether, the present data demonstrate that DHEA inhibits T-channels by a Gi protein dependent pathway. DHEA-induced alteration in T-channel activity could thus account for its therapeutic action and/or physiological effects.
Islet Transplantation under the Kidney Capsule Corrects the Defects in Glycogen Metabolism in Both Liver and Muscle of Streptozocin-Diabetic Rats (2002)

Insulin-deficient rats are characterized by multiple defects in the pathway of glycogen synthesis and breakdown in both liver and skeletal muscle. The aim of this study was to clarify whether islet transplantation under the kidney capsule, which is associated with delivery of insulin into the peripheral circulation, is able to normalize glycogen metabolism in liver and muscle of streptozotocin-diabetic rats. Three groups of male Lewis rats were studied under fasting condition: controls, untreated diabetics, and islet transplanted diabetics. Glycogen content, glucose-6-phosphate concentration, and glycogen synthase activity were measured in both liver and skeletal muscle. Untreated diabetic rats were characterized by an increase in glycogen content of 178% and a reduction of glucose-6-phosphate level of 50%. Both glycogen and glucose-6-phosphate contents were restored to normal in transplanted diabetic rats. Active glycogen synthase (0.35 +/- 0.1 nmol/min/mg) and activity ratio (0.22 +/- 0.04) were significantly impaired compared with controls (0.99 +/- 0.2 nmol/min/mg and 0.43 +/- 0.06, respectively) and were normalized by islet transplantation. In the skeletal muscle, glycogen content was similar in the three groups of animals, whereas muscle glucose-6-phosphate level was reduced by 28% and glycogen synthase was in a less active state in the untreated diabetic rats. Both the glucose-6-phosphate concentration and the kinetic profile of glycogen synthase were normalized by islet transplantation. In conclusion, islet transplantation under the kidney capsule corrects the diabetes-induced abnormalities in glycogen and glucose-6-phosphate content and glycogen synthase activity in both liver and skeletal muscle.
Molecular biology of double‐minute chromosomes (1993)

Double-minute chromosomes play a critical role in tumor cell genetics where they are frequently associated with the overexpression of oncogene products. They have been observed for many years in light microscopic examinations of metaphase chromosomes from tumor cells, but their origin remains unknown and is the subject of considerable speculation. However, molecular details of their structure and organization can now be described in conjunction with the microscopic examinations, to allow an evaluation of the various models that have been developed to explain the genesis of double-minutes. The evidence now favors simple models that invoke chromosome breakage and circularization of very large acentric chromosome fragments, permitting unequal segregation of the genes on the fragment during cell division. If there is selection for overexpression of one of the genes on the fragment, daughter cells with more fragments will grow faster than daughter cells with fewer fragments, and over time the population of cells will come to contain many double-minutes per cell.
Universal method for robust detection of circadian state from gene expression (2018)

Circadian clocks play a key role in regulating a vast array of biological processes, with significant implications for human health. Accurate assessment of physiological time using transcriptional biomarkers found in human blood can significantly improve diagnosis of circadian disorders and optimize the delivery time of therapeutic treatments. To be useful, such a test must be accurate, minimally burdensome to the patient, and readily generalizable to new data. A major obstacle in development of gene expression biomarker tests is the diversity of measurement platforms and the inherent variability of the data, often resulting in predictors that perform well in the original datasets but cannot be universally applied to new samples collected in other settings. Here, we introduce TimeSignature, an algorithm that robustly infers circadian time from gene expression. We demonstrate its application in data from three independent studies using distinct microarrays and further validate it against a new set of samples profiled by RNA-sequencing. Our results show that TimeSignature is more accurate and efficient than competing methods, estimating circadian time to within 2 h for the majority of samples. Importantly, we demonstrate that once trained on data from a single study, the resulting predictor can be universally applied to yield highly accurate results in new data from other studies independent of differences in study population, patient protocol, or assay platform without renormalizing the data or retraining. This feature is unique among expression-based predictors and addresses a major challenge in the development of generalizable, clinically useful tests.
The genus lavandula (2005)

Long prized by the fragrance industry for its essential oils, the genus is steadily increasing in popularity among gardeners and horticulturists worldwide. This is the first full treatment of this important genus to be undertaken since 1937. It treats 39 species and their cultivars and hybrids, presenting their taxonomy, distribution, and the history of their cultivation. With several useful appendices, as well as chapters on cultivation, propagation, and pests and diseases, The Genus Lavandula is a comprehensive and authoritative account of this important genus. Exquisite paintings from the Royal Botanic Gardens, Kew, complement the text.
The Detection of 3-Indoleacetic Acid in Cauliflower Heads. Chromatographic Behavior of Some Indole Compounds<sup>1,2</sup> (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Detection of 3-Indoleacetic Acid in Cauliflower Heads. Chromatographic Behavior of Some Indole Compounds1,2Lowell E. Weller, Sylvan H. Wittwer, and Harold M. SellCite this: J. Am. Chem. Soc. 1954, 76, 2, 629–630Publication Date (Print):January 1, 1954Publication History Published online1 May 2002Published inissue 1 January 1954https://pubs.acs.org/doi/10.1021/ja01631a104https://doi.org/10.1021/ja01631a104research-articleACS PublicationsRequest reuse permissionsArticle Views61Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Influence of Thermal Conditioning Media on Charpy Specimen Test Temperature (1990)

The Charpy V-notch (CVN) impact test is used extensively for determining the toughness of structural materials. Research programs in many technologies concerned with structural integrity perform such testing to obtain Charpy energy vs temperature curves. American Society for Testing and Materials Method E 23 includes rather strict requirements regarding determination and control of specimen test temperature. It specifies minimum soaking times dependent on the use of liquids or gases as the medium for thermally conditioning the specimen. The method also requires that impact of the specimen occur within 5 s of removal from the conditioning medium. It does not, however, provide guidance regarding choice of conditioning media. This investigation was primarily conducted to investigate the changes in specimen temperature which occur when water is used for thermal conditioning. A standard CVN impact specimen of low-alloy steel was instrumented with surface-mounted and embedded thermocouples. Dependent on the media used, the specimen was heated or cooled to selected temperatures in the range-100 to 100°C using cold nitrogen gas, heated air, acetone and dry ice, methanol and dry ice, heated oil, or heated water. After temperature stabilization, the specimen was removed from the conditioning medium while the temperatures were recorded four times per second from all thermocouples using a data acquisition system and a computer. The results show that evaporative cooling causes significant changes in the specimen temperatures when water is used for conditioning. Conditioning in the other media did not result in such significant changes. The results demonstrate that, even within the guidelines of E 23, significant test temperature changes can occur which may substantially affect the Charpy impact test results if water is used for temperature conditioning.
webSPADE: a parallel sequence mining algorithm to analyze web log data (2003)

Enterprise-class web sites receive a large amount of traffic, from both registered and anonymous users. Data warehouses are built to store and help analyze the click streams within this traffic to provide companies with valuable insights into the behavior of their customers. This article proposes a parallel sequence mining algorithm, webSPADE, to analyze the click streams found in site web logs. In this process, raw web logs are first cleaned and inserted into a data warehouse. The click streams are then mined by webSPADE. An innovative web-based front-end is used to visualize and query the sequence mining results. The webSPADE algorithm is currently used by Verizon to analyze the daily traffic of the Verizon.com web site.
Role of ERBB-2 in Breast Cancer Progression. (1995)

Abstract : Overexpression of growth factors and growth factor receptors is frequently associated with loss of estrogen receptor (ER) in human breast cancer, leading to the hypothesis that constitutive expression of these proteins might decrease dependence on estrogen. We have previously investigated the role of one putative growth factor receptor, c-erbE-2, in loss of hormone dependence by transfection of the c-erbB-2 cDNA into ER+ human breast cancer cells. We found that the size of the tumors formed correlated with the degree of tyrosine phosphorylation of the transfected protein. We hypothesized that an increase in tyrosine phosphor- ylation might increase the tumorigenicity of the cells. We therefore transfected ER+ MCF-7 cells with wild type and constitutively active mutant c-erbB-2 cDNAs. We found that we were able to stably overexpress the wild type protein only in the absence of estrogen, and that we were unable to stably overexpress the mutant protein under any growth conditions. Subsequent transfection of the mutant c-erbB-2 using a tetracycline-regulated gene expression system suggested that constitutive expression of this protein might induce apoptosis in breast cancer cells. These results suggest an important role for c-erbB-2 in regulation of the growth of breast cancer cells.
The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders (2019)

Mood disorders are the most prevalent mental conditions encountered in psychiatric practice. Numerous patients suffering from mood disorders present with treatment-resistant forms of depression, co-morbid anxiety, other psychiatric disorders and bipolar disorders. Standardized essential oils (such as that of Lavender officinalis) have been shown to exert clinical efficacy in treating anxiety disorders. As endocannabinoids are suggested to play an important role in major depression, generalized anxiety and bipolar disorders, Cannabis sativa was suggested for their treatment. The endocannabinoid system is widely distributed throughout the body including the brain, modulating many functions. It is involved in mood and related disorders, and its activity may be modified by exogenous cannabinoids. CB1 and CB2 receptors primarily serve as the binding sites for endocannabinoids as well as for phytocannabinoids, produced by cannabis inflorescences. However, 'cannabis' is not a single compound product but is known for its complicated molecular profile, producing a plethora of phytocannabinoids alongside a vast array of terpenes. Thus, the "entourage effect" is the suggested positive contribution derived from the addition of terpenes to cannabinoids. Here, we review the literature on the effects of cannabinoids and discuss the possibility of enhancing cannabinoid activity on psychiatric symptoms by the addition of terpenes and terpenoids. Possible underlying mechanisms for the anti-depressant and anxiolytic effects are reviewed. These natural products may be an important potential source for new medications for the treatment of mood and anxiety disorders.
W-band InGaAs HEMT low noise amplifiers (1990)

The authors report 0.15- mu m gate length GaAs-based and InP-based InGaAs channel high-electron-mobility transistors (HEMTs) that have exhibited state-of-the-art noise and gain performance well up to 100 GHz. 94-GHz noise figures of 2.4 and 1.4 dB with gains of 5.4 and 6.5 dB have been measured from GaAs- and InP-based HEMTs, respectively. High-performance W-band multistage amplifiers have been built using these devices. A two-stage GaAs-based amplifier exhibits a noise figure of 4.2 dB with a gain of 9.7 dB at 93 GHz, and a three-stage amplifier yields a 4.5-dB noise figure with 14.8-dB gain at 94 GHz. The best two-stage amplifier built with InP-based HEMTs exhibits a minimum noise figure of 3.2 dB with a gain of 11.5+or-0.4 dB from 88 to 96 GHz. A noise figure as low as 3.3 dB with gain of 17.3+or-0.5 dB from 88 to 96 GHz has also been demonstrated from a three-stage amplifier. The characteristics and performance of both devices are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Mechanical Tests of Free-Standing Aluminum Microbeams for MEMS Application (2001)

We studied mechanical properties and alloy effects of free-standing aluminum microbeams (50 × 500 × 2 μm) in a piezo-actuator-driven test apparatus with a load resolution of ±0.2 mN and a displacement resolution of ±10 nm. Pure Al and Al-2%Ti microbeams were fabricated using micromachining techniques. In tensile tests, we found the yield strength to be approximately 120 MPa for the pure Al beams, and approximately 75% higher for the alloyed beams. We examined the results with respect to those of bulk materials and thin films adhered to substrates. In stress relaxation tests, we observed a load drop of 56% over 10 min for the pure Al beams. We attributed this to grain boundary sliding and the nature of a free-standing thin film, i.e., the absence of a substrate. For the alloyed beams, the load drop was only 16%. We believed the difference was due to Al3Ti precipitates formed at grain boundaries, which hindered dislocation movements. We used TEM to reveal the microstructural features of the microbeams.
Location of an F-pilin pool in the inner membrane (1981)

Polyacrylamide gel analysis of [35S]methionine-labeled membrane preparations from Escherichia coli has revealed the presence of five polypeptides present only in the membranes of cells containing the conjugative plasmid F. In addition to the previously reported product of traT, polypeptides migrating with apparent molecular weights of 100,000, 23,500, 12,000, and 7,000 were resolved. Membrane preparations from F traJ mutants lacked these polypeptides, indicating that all of these proteins are tra gene products. The 7,000-molecular-weight polypeptide comigrated with unlabeled purified F-pilin protein. About 4 to 5% of the total radioactive label in whole membrane preparations was present in this polypeptide, indicating the existence of a substantial pool of membrane-associated F-pilin. The polypeptide could be extracted from whole membrane preparations with Triton X-100 and was found in the inner membrane fraction of membranes separated by sucrose density centrifugation.
Harmonic Signatures of Static Eccentricities in the Stator Voltages and in the Rotor Current of No-Load Salient-Pole Synchronous Generators (2010)

This paper shows that a static eccentricity makes rise a double fundamental frequency ripple in the rotor current of salient-pole synchronous machines. This ripple leads, under conditions ruled by the stator windings, to precise signatures in the no-load voltage spectrum. Both rotor current ripple and voltage harmonics can be used for diagnosis. The fault-related voltage harmonics are theoretically previewed in this paper through analysis of the windings. Simulations performed by using the winding function approach confirm the theoretical predictions. A four-pole 15-kVA generator was used for experiments, featuring an innovative flange with exact and easy regulation of mixed-type eccentricities. Rotor current monitoring has advantages of single-sensor measure and accentuate fault sensitivity. Experiments also showed an additional rotor-rotation frequency ripple in the rotor current, in case of mixed-type fault.
p-Methoxybenzyl Ethers as Acid-Labile Protecting Groups in Oligosaccharide Synthesis (1995)

The p-methoxybenzyl (PMB) group can be removed selectively with trifluoroacetic acid (TFA) in the presence of multiple glycosidic linkages as well as other sensitive functionality used in oligosaccharide synthesis.
Evaluation of Roasting and Brewing effect on AntinutritionalDiterpenes-Cafestol and Kahweol in Coffee. (2011)

Coffee brew prepared from roasted coffee beans contains quite a lot of compounds
which are known to influence consumers health. Among these, cafestol and kahweol are
associated with lipid fraction of coffee and reported to be responsible for elevated serum
cholesterol levels in people who drink more coffee. Aim : A study has been taken up to find out
the influence of roasting and brewing methods on antinutritional diterpenes, in coffee brew.
Methodology : Coffee bean samples were roasted at different temperatures and the brew
prepared from these beans was analyzed for cafestol and kahweol profiles by using HPLC.
Similarly coffee brew was prepared by mocha, filter, espresso, french press etc., and their
diterpene profiles were analyzed by HPLC. Results: There was a substantial difference in cafestol
and kahweol profiles in brews with highest content of cafestol and kahweol in Turkish-style and
French press coffee. Similarly higher roasting temperatures and prolonged roasting times had
significant influence on diterpenes profiles in roasted beans.
Effects of phase shift between two photo-alignment substrates on diffraction properties in liquid crystalline grating cells (2009)

Diffractive optical devices using low-molar-mass liquid crystals are of great important for realizing numerical optical functions such as optical memory and information systems. In the present study the liquid crystalline gratings have been fabricated using a pair of photo-alignment substrates, and effects of the phase shift between the two photo-alignment substrates on the diffraction properties have been investigated. The liquid crystalline grating has been constructed with variable polarization dependence that can be controlled by the phase shift between the two photo-alignment substrates and twisted angles of the nematic directors. The theoretical considerations were also performed using the elastic continuum theory, Jones calculus, and diffraction theory. A guiding principle that controls the diffraction properties of the liquid crystalline grating cell was successfully presented.
Action-oriented Benchmarking: Using the CEUS Database to Benchmark Commercial Buildings in California (2008)

ABSTRACT The 2006 Commercial End Use Survey (CEUS) database developed by the California Energy Commission is a far richer source of energy end-use data for non-residential buildings than has previously been available, and opens the possibility of creating new and more powerful energy benchmarking processes and tools. In this article—Part 2 of a two-part series—we describe the methodology and selected results from an action-oriented benchmarking approach using the new CEUS database. This approach goes beyond whole-building energy benchmarking to more advanced end-use and component-level benchmarking that enables users to identify and prioritize specific energy efficiency opportunities—an improvement on benchmarking tools typically in use today.
Inverse polarizing effect of subwavelength metallic gratings in deep ultraviolet band (2011)

Using subwavelength structures to manipulate the polarization of deep ultraviolet light is generally known as difficult with the current nano-fabrication technologies. An aluminum grating with period close to the incident wavelength is designed and experimentally evidenced to exhibit a pronounced inverse polarizing effect in the deep ultraviolet band. By using the Fourier modal method and planar waveguide theory, we show that the main contributor to the inverse polarizing effect is the excitation of surface plasmons on the front surface of the grating.