gebhart/patrepeval huggingface dataset:
A New Pacemaker Algorithm for Continuous Capture Verification and Automatic Threshold Determination: Elimination of Pacemaker Afterpotential Utilizing a Triphasic Charge Balancing System (1992)

A new pacemaker algorithm designed to automatically verify pacemaker capture and determine pacing threshold by detection of a stimulus evoked potential was studied in 20 patients undergoing permanent pacemaker implantation. To eliminate pacing stimulus afterpotential and detect an evoked response, a hardware feedback circuit and a software template matching algorithm were used to produce a triphasic charge-balanced pacing pulse. After charge balancing the pacing lead, a residual artifact is measured. A capture window is defined as the area integral of the first 24 msec of the evoked depolarization, and a capture threshold as one third the amplitude of the capture window. The maximum allowable residual artifact is one eighth the amplitude of the capture window. Once the stimulus afterpotential is eliminated and the evoked response detected, capture threshold is automatically and continuously determined and the algorithm adds a 0.8-V safety margin to the pacemaker output. This algorithm was run automatically and after simulated loss of capture, produced by manually decreasing pacer output below threshold, in the bipolar (13 patients) and unipolar (20 patients) pacing modes. In each patient loss of capture was immediately detected. The data were consistent (P = NS) between algorithm runs. During unipolar pacing the area integral of the first 24 msec of the evoked response was 412 +/- 137 versus 413 +/- 144 and the residual artifact 5.8 +/- 4.8 versus 8.1 +/- 7.5. The resulting ratio (signal/noise) of the two parameters was 150 +/- 141 versus 145 +/- 181. Automatically determined threshold was 0.69 +/- 0.43 V versus 0.69 +/- 0.42.(ABSTRACT TRUNCATED AT 250 WORDS)
Clinical Laboratory Medicine (2002)

annum, and three clerks each at $1,800 per annum, and three messengers each at $900 per annum.Section 3.That the director and specialists, it necessary for the proper discharge of their duties, may place themselves in communication with state and municipal and other officials of this and other countries.Section 4. That for the proper equipment of and carrying on the work of said laboratory, the temporary
Osteopontin-derived Peptide SVVYGLR Induces Angiogenesis In Vivo (2004)

Our previous study reported that an osteopontin-derived peptide SVVYGLR activates the adhesion, migration and tube formation abilities of endothelial cells in vitro. The present study investigated angiogenesis due to synthetic SVVYGLR and mutant peptides in vivo. Mutant peptides (n = 7) were synthesized by substituting alanine (A) for one of the 7 amino acids comprising SVVYGLR. In dorsal air sac assay, mouse dorsal skin 5 days after implantation of a chamber filled with SVVYGLR had approximately the same number of newly formed blood vessels to that filled with vascular endothelial growth factor (VEGF). The ability of angiogenesis due to SVVAGLR was significantly lower than that due to other 6 mutant peptides and SVVYGLR. This indicates that tyrosine (Y) plays an important role in angiogenesis due to SVVYGLR.
Performance Comparison of 1.5kV 4H-SiC Buried Channel and Lateral Channel JBS Rectifiers (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
“Eph receptor signalling; dimerisation just isn't enough” (2005)

(2005). “Eph receptor signalling; dimerisation just isn't enough”. Growth Factors: Vol. 23, No. 1, pp. 67-76.
Efficacy of topical treatments for cutaneous warts: a meta-analysis and pooled analysis of randomized controlled trials (2011)

Many topical treatments for cutaneous warts exist and previous reviews of trials did not follow intention-to-treat (ITT) principles for analysis. We aimed to perform a meta-analysis and pooled analysis of randomized controlled trials (RCTs) of topical treatment for cutaneous warts using ITT principles. Systematic electronic searches (Cochrane library, Medline, Embase, Clinical trial registers) were conducted in May 2009. Included trials reported completed cure of warts and data were extracted from these trials. We performed random-effects meta-analysis and assessed heterogeneity using the I(2) statistic and conducted a pooled analysis of each treatment. We found 77 relevant studies of which the majority were of low methodological quality. Salicylic acid (SA) was superior to placebo with a risk ratio (RR) for cure of 1·60 [95% confidence interval (CI) 1·15-2·24]. Cryotherapy was not statistically better than placebo, RR 0·89 (95% CI 0·27-2·92), but aggressive cryotherapy was significantly better than gentle cryotherapy with a RR of 2·06 (95% 1·20-3·52). Combined therapy of SA and cryotherapy had a higher cure rate than either SA or cryotherapy alone. The results of the pooled analysis found a cure rate of 23% (5-73%) in placebo trials, 52% (0-87%) in SA trials, 49% (0-69%) in cryotherapy trials, 54% (45-75%) in aggressive cryotherapy trials and 58% (38-78%) in the combined cryotherapy and SA trials. Aside from the use of SA and aggressive cryotherapy there is insufficient evidence from RCTs to support the use of other therapies. Higher quality evidence is needed to evaluate other therapies.
Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata (2003)

The ethanol extract of the leaves of Tabernaemontana divaricata (double flower variety) provided a total of 23 alkaloids, including the new aspidosperma alkaloids, taberhanine, voafinine, N-methylvoafinine, voafinidine, voalenine and the new bisindole alkaloid, conophyllinine in addition to the previously known, biologically active bisindole, conophylline and its congener, conofoline. The structures of the new alkaloids were established by spectroscopic methods. The preparation and characterization of the corresponding quinones of the biologically active bisindoles are also described in relation to a structure-activity study of these compounds with respect to their action in stimulating insulin expression.
An optimization procedure for the pultrusion process based on a finite element formulation (2002)

Abstract Composite materials are manufactured by different processes. In all, the process variables have to be analyzed in order to obtain a part with uniform mechanical properties. In the pultrusion process, two variables are the most important: the pulling speed of resin‐impregnated fibers and the temperature profile (boundary condition) imposed on the mold wall. Mathematical modeling of this process results in partial differential equations that are solved here by a detailed procedure based on the Galerkin weighted residual finite element method. The combination of the Picard and Newton‐Raphson methods with an analytical Jacobian calculation proves to be robust, and a mesh adaptation procedure is presented in order to avoid integration errors during the process optimization. The two earlier‐mentioned variables are optimized by the Simulated Annealing method with some constraints, such as a minimum degree of cure at the end of the process, and the resin degradation (the part temperature cannot be higher than the resin degradation temperature at any time during the whole process). Herein, the proposed objective function is an economic criterion instead of the pulling speed of resin‐impregnated fibers, used in the majority of papers.
A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool (2014)

Altogether our results uncovered a small noncoding RNA signature in microvesicles isolated from GBM patient serum that could be used as a fast and reliable differential diagnostic biomarker.
Iron Curtain Christians: The Church in Communist Countries Today. By Kurt Hutten. Minneapolis: Augsburg Publishing House, 1967. 495 pp. $10.00 (1968)

Iron Curtain Christians: The Church in Communist Countries Today. By Kurt Hutten. Minneapolis: Augsburg Publishing House, 1967. 495 pp. $10.00 Get access Ralph L. Lynn Ralph L. Lynn Search for other works by this author on: Oxford Academic Google Scholar Journal of Church and State, Volume 10, Issue 3, Autumn 1968, Pages 459–460, https://doi.org/10.1093/jcs/10.3.459 Published: 01 October 1968
A personalized approach to web privacy: awareness, attitudes and actions (2011)

Purpose The purpose of this paper is to take a novel approach to help users better understand and be more aware of what third parties are learning about them as they browse the web. Design/methodology/approach The approach the authors take is to personalize the awareness by using JavaScript embedded in a web page to examine portions of a user's web-browser history in order to ascertain web sites that the user has visited. The authors then personalize information reported to the user about what third-party sites are tracking the user's behavior along with demographic information these sites may be inferring from these visited sites and the user's geographic location. Findings It was found that 63 percent of users agreed with a statement of concern for third parties monitoring activities, about half of the respondents agreed with a concern for knowledge about a user's location and a little more than half agreed to concern about inference of demographic information. It was found that females are more concerned about these issues than males. In terms of possible actions, a majority of users report using an ad blocker tool and even more delete cookies at least some amount of time. Using an opt-out mechanism or removing browser history is done by less than 20 percent of users. Despite expressing more concern for information known by third parties, females are not significantly more likely to take actions that may limit what is leaked to these third parties. A contributor to this discrepancy is that females were much less likely to know their settings for many of the actions, indicating less familiarity with them. Social implications Web privacy is an important social issue so helping users to better understand tracking of their actions, along with what actions can be taken to limit tracking, is important. Originality/value The paper takes an original approach to helping users understand what third parties learn about them and follows up that approach with a survey of user attitudes and actions on this important topic.
Recognition of Activities of Daily Living with Egocentric Vision: A Review (2016)

Video-based recognition of activities of daily living (ADLs) is being used in ambient assisted living systems in order to support the independent living of older people. However, current systems based on cameras located in the environment present a number of problems, such as occlusions and a limited field of view. Recently, wearable cameras have begun to be exploited. This paper presents a review of the state of the art of egocentric vision systems for the recognition of ADLs following a hierarchical structure: motion, action and activity levels, where each level provides higher semantic information and involves a longer time frame. The current egocentric vision literature suggests that ADLs recognition is mainly driven by the objects present in the scene, especially those associated with specific tasks. However, although object-based approaches have proven popular, object recognition remains a challenge due to the intra-class variations found in unconstrained scenarios. As a consequence, the performance of current systems is far from satisfactory.
Robust Multicast Beamforming for Spectrum Sharing-Based Cognitive Radios (2011)

We consider a robust downlink beamforming optimization problem for secondary multicast transmission in a multiple-input multiple-output (MIMO) spectrum sharing cognitive radio (CR) network. The minimization of transmit power is formulated subject to both quality-of-service (QoS) constraints on the secondary receivers and interference temperature constraints on the primary users, under the assumption of imperfect channel state information (CSI). The problem is a nonconvex quadratically constrained quadratic program (QCQP), and in general it is hard to achieve the global optimality. As a compromise, we present two randomized approximation algorithms for the problem via convex optimization techniques. Apart from the general setting of the robust beamforming problem, we identify one interesting special case, the robust problem of which can be solved efficiently. Simulation results are presented to demonstrate the performance gains of the proposed algorithms over an existing robust design.
A Simplified Technique for Correcting Mitral Valve Regurgitation via Minimally Invasive Approach (2018)

Mitral valve regurgitation may require complex repair techniques that are challenging in minimally invasive and may expose patients to prolonged cardiopulmonary bypass and cross-clamp times. Here, we present a stepwise operative approach that may facilitate the repair of the mitral valve in a minimally invasive fashion and may be carried out even when multiple posterior segments are involved. This how-to-do article presents a method that was performed in 148 patients that were referred to our institution for severe organic mitral regurgitation between 2008 and 2016. At mean ± SD follow-up of 45.5 ± 27 months, freedom from recurrent of mitral regurgitation 2+ or greater and reoperation was 95.2%.
A Newly Developed Correction System of Transmission Distortion with Vertical Interval Reference Signal (1979)

Recent television receivers have improved very much in many points and have become able to produce fairly good pictures. However, the stability of tint and color saturation depending on transmission distortion are still a problem to be solved. In order to have improvement in this area, FCC has approved the broadcasting of Vertical Interval Reference (VIR) Signal in 1974.
A Study on the Application of CRUDTRAN Code in Primary Systems of Domestic Pressurized Heavy-Water Reactors for Prediction of Radiation Source Term (2016)

The importance of developing a source-term assessment technology has been emphasized owing to the decommissioning of Kori nuclear power plant (NPP) Unit 1 and the increase of deteriorated NPPs. We analyzed the behavioral mechanism of corrosion products in the primary system of a pressurized heavy-water reactor-type NPP. In addition, to check the possibility of applying the CRUDTRAN code to a Canadian Deuterium Uranium Reactor (CANDU)-type NPP, the type was assessed using collected domestic onsite data. With the assessment results, it was possible to predict trends according to operating cycles. Values estimated using the code were similar to the measured values. The results of this study are expected to be used to manage the radiation exposures of operators in high-radiation areas and to predict decommissioning processes in the primary system.
Some Recent Advances in the Understanding and Prediction of Turbomachine Subsonic Stall Flutter (1985)

In this paper, some recent advances in the understanding and prediction of subsonic flutter of jet engine fan rotor blades are reviewed. Among the topics discussed are (i) the experimental evidence of mistuning in flutter responses, (ii) new and promising unsteady aerodynamic models for subsonic stall flutter prediction, (iii) an overview of flutter prediction methodologies, and (iv) a new research effort directed toward understanding the mistuning effect on subsonic stall flutter of shrouded fans. A particular shrouded fan of advanced design is examined in the detailed technical discussion.
A Fractal Wormhole Model for Cold Heavy Oil Production (2005)

Abstract Wormholes are believed to be generated during the process of cold production and are responsible for enhanced production rates. Understanding the wormhole patterns generated inside the reservoir formation is critical to improve the recovery efficiency and to model the fluid flow behaviour in the cold production process. In this paper, we have proposed that the wormhole growth can be described by the Diffusion-Limited Aggregation (DLA) model, which naturally relates to a broad variety of branchinggrowth patterns through the physics of the processes. The physical processes that were described using fractal models include the following: the growth of a drainage network; the formation of cavities; the dissolution of porous materials; and, the growth of random dendrites in the thin films. The DLA model has important implications in petroleum geology and engineering. Based on the experimental results published in the literature, which were specifically designed to investigate the wormhole dynamics by a Computed-Tomography X-Ray scanner, the wormhole diameter distribution along the wormhole path has been analyzed using the Area Version of Gaussian Function. Then, the material balance method has been applied to the sand production data to determine the possible range of the wormhole structure around the wellbore, assuming that the sand particles are solely produced along the paths of wormholes. Finally, a numerical method has been developed to analyze the field sand production data. The studies have shown that the fractal wormhole model can be used to diagnose the characteristics of the wormhole structures, and that it can be applied to optimize well placement in cold heavy oil production. The model will greatly enhance the analyses of the inflow performance and the pressure response of wells in wormholed reservoirs. Results acquired from this study can also be implemented in field scale numerical simulations for the cold flow process. Introduction Cold production is a non-thermal process in which sand is aggressively produced to reach a higher oil production rate. In the cold flow process, sand and oil are produced together under primary conditions and oil production rates can typically increase by a factor of 10 or more(1–5). For example, primary oil production rates of 8 – 12 m3/d are roughly 10 times greater than those calculated for the radial flow in the Celtic field using Darcy's law(2). The unusual sand production in cold production was observed in several oil fields. Records have indicated that the production of about 708 m3 of sand in the first four months, and in nearly all the wells in S.E. Pauls Valley Field, Oklahoma, produced 10 – 50% sand initially, declining a few months later to 0.1 – 2%, regardless of completion method(5). The cumulative gross fluid production of about 9,000 m3 with an associated sand production of 200 m3 within a period of 1,000 days was observed in the Lindbergh and Frog Lake Fields, Alberta(1).
Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer (2014)

The current view of cancer progression highlights that cancer cells must undergo through a post-translational regulation and metabolic reprogramming to progress in an unfriendly environment. In here, the importance of neddylation modification in liver cancer was investigated. We found that hepatic neddylation was specifically enriched in liver cancer patients with bad prognosis. In addition, the treatment with the neddylation inhibitor MLN4924 in Phb1-KO mice, an animal model of hepatocellular carcinoma showing elevated neddylation, reverted the malignant phenotype. Tumor cell death in vivo translating into liver tumor regression was associated with augmented phosphatidylcholine synthesis by the PEMT pathway, known as a liver-specific tumor suppressor, and restored mitochondrial function and TCA cycle flux. Otherwise, in protumoral hepatocytes, neddylation inhibition resulted in metabolic reprogramming rendering a decrease in oxidative phosphorylation and concomitant tumor cell apoptosis. Moreover, Akt and LKB1, hallmarks of proliferative metabolism, were altered in liver cancer being new targets of neddylation. Importantly, we show that neddylation-induced metabolic reprogramming and apoptosis were dependent on LKB1 and Akt stabilization. Overall, our results implicate neddylation/signaling/metabolism, partly mediated by LKB1 and Akt, in the development of liver cancer, paving the way for novel therapeutic approaches targeting neddylation in hepatocellular carcinoma.
A Simple Electrocardiographic Algorithm for Detecting Ventricular Tachycardia (1997)

The purpose of this study was to determine whether a simple ECG algorithm could be developed for predicting susceptibility to ventricular tachyarrhythmias (VT) as defined by sustained spontaneous or inducible VT. Two different QT dispersion algorithms were determined by the difference between the longest and shortest QT interval measured in three orthogonal leads (I, aVF, V1; QTD3), and at least 11 of 12 leads (QTD12) from the 12-lead ECG. These QT dispersion algorithms were investigated (with and without the QRS duration from the 12-lead ECG) and compared to the signal-averaged ECG (SAECG) in order to determine their sensitivity and specificity for detecting VT. Only patients who underwent SAECG and were referred for programmed electrical stimulation were included in this study. A positive SAECG was defined by filtered QRS duration > 114 ms, and/or low amplitude signal duration > 38 ms, and/or root mean square voltage in the last 40 ms of < 20 microV. Sixty patients were enrolled in this study with a mean age of 63 +/- 2 years. Fifty-five percent of the patients had coronary artery disease. A simple ECG algorithm consisting of the sum of QTD3 plus the QRS duration had a sensitivity and specificity of 90% and 63%, respectively, wheras the SAECG had a sensitivity and specificity of 60% and 63%, respectively (P = 0.022). We conclude that a simple ECG algorithm is more sensitive than the SAECG for predicting VT. This algorithm combines two easily measured variables obtained from the 12-lead ECG, and can easily be performed without expensive computer equipment.
Purification and Properties of a Cellobiose Phosphorylase (CepA) and a Cellodextrin Phosphorylase (CepB) from the Cellulolytic Thermophile <i>Clostridium Stercorarium</i> (1997)

Two phosphorolytic enzymes displaying activity towards the soluble cellulose degradation products cellobiose and cellodextrins were purified from the crude extract of the cellulolytic thermophile Clostridium stercorarium. Both phosphorylases have monomeric structures with molecular masses of 93 and 91 kDa, respectively. Although the N-terminal amino acid sequences are highly similar, a clear distinction of the two enzymes could be made on the basis of their substrate specificities: the enzyme designated cellobiose phosphorylase cleaved exclusively the disaccharide substrate, whereas the enzyme designated cellodextrin phosphorylase accepted only oligosaccharides as substrates. Kinetic constants were determined for the cleavage of cellobiose and cellodextrins. Maximal activity was observed at 65 degrees C in the pH range 6.0-7.0 for both enzymes. The sequences of the genes cepA and cepB encoding the cellobiose phosphorylase and the cellodextrin phosphorylase, respectively, have been submitted to the GenBank database.