gebhart/patrepeval huggingface dataset:
Mechanistic Studies of Catalytic Olefin Dimerization Reactions Using Electrophilic η<sup>3</sup>-Allyl−Palladium(II) Complexes (1996)

The dimerization of olefins by well-defined cationic η3-allyl−palladium complexes of the type [(C3H5)Pd(L)(PR3)]+[BAr‘4]- (Ar‘ = [3,5-C6H3(CF3)2]; L = OEt2, H2O; R = cyclohexyl (Cy), n-butyl (nBu)) has been studied. These complexes react with ethylene or methyl acrylate at −80 °C with loss of L to form the η2-olefin complexes [(C3H5)Pd(η2-olefin)(PR3)]+[BAr‘4]- (olefin = H2CCH2, CH2CHC(O)OCH3). Upon warming, allyl−olefin coupling occurs. The dimerization of ethylene occurs rapidly at 0 °C with an observable ethyl−ethylene intermediate [(C2H5)Pd(C2H4)2(PCy3)]+[BAr‘4]-. Methyl acrylate reacts to form a stable acrylate chelate complex, [(CH3O(O)CCH2CH2)Pd(CH2CHC(O)OCH3)(PR3)]+[BAr‘4]-, which is the catalyst resting state for methyl acrylate dimerization which occurs at room temperature to give predominantly trans-dimethyl-2-hexenedioate.
THE DESIGN AND CONSTRUCTION OF THERMAL FLOWMETERS (1962)

A thermal flowmeter was designed and tested which will measure a wide range of flow rates for highly corrosive gases. Response to flow rate changes is fast. The pararaeters for changing the size and response to the flowmeter were evaluated. (auth)
Recovered Bandgap Absorption of Single‐Walled Carbon Nanotubes in Acetone and Alcohols (2005)

The bandgap optical absorption of single-walled carbon nanotubes (SWNTs) is significantly enhanced by acetone and alcohols. Based on their ability to strip off adsorbates from the nanotube surfaces, these solvents can almost fully recover the optical absorption (see Figure). The distinct absorption recovery can be used to characteristically distinguish a variety of organic solvents, and may find application in chemical sensors.
Multicolored, Tb<sup>3+</sup>-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities (2015)

Kinase signaling is a major mechanism driving many cancers. While many inhibitors have been developed and are employed in the clinic, resistance due to crosstalk and pathway reprogramming is an emerging problem. High-throughput assays to detect multiple pathway kinases simultaneously could better model these complex relationships and enable drug development to combat this type of resistance. We developed a strategy to take advantage of time-resolved luminescence of Tb(3+)-chelated phosphotyrosine-containing peptides, which facilitated efficient energy transfer to small molecule fluorophores conjugated to the peptides to produce orthogonally colored biosensors for two different kinases. This enabled multiplexed detection with high signal-to-noise in a high-throughput-compatible format. This proof-of-concept study provides a platform that could be applied to other lanthanide metal and fluorophore combinations to achieve even greater multiplexing without the need for phosphospecific antibodies.
Generation and transmission of multiband and multi-gigabit 60-GHz MMW signals in an RoF system with frequency quintupling technique (2013)

We propose and experimentally demonstrate a cost-effective radio-over-fiber (RoF) system to simultaneously generate and transmit multiband and multi-gigabit 60-GHz millimeter wave (MMW) signals using frequency quintupling technique. Multiband signals at 56-GHz and 60-GHz are realized with two cascaded single-drive Mach-Zehnder modulators (MZMs), where phase control is not required. Furthermore, only low-frequency (≤12GHz) optical and electrical devices are used in the central station (CS), which enable a cost-effective system. At the user-terminal, two-stage down-conversions are employed by envelope detection (ED) and intermediate frequency (IF) mixing, eliminating expensive high-speed synthesizer and critical phase control components. Error-free performances are achieved for the multiband MMW signals after 50-km single-mode fiber (SMF) and 10-ft wireless link transmissions.
(.pi.-Allyl)palladium complexes of norcamphene. Structure and reactivity (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT(.pi.-Allyl)palladium complexes of norcamphene. Structure and reactivityS. A. Godleski, K. B. Gundlach, H. Y. Ho, E. Keinan, and F. FrolowCite this: Organometallics 1984, 3, 1, 21–28Publication Date (Print):January 1, 1984Publication History Published online1 May 2002Published inissue 1 January 1984https://pubs.acs.org/doi/10.1021/om00079a006https://doi.org/10.1021/om00079a006research-articleACS PublicationsRequest reuse permissionsArticle Views143Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Peripheral Blood-Derived Mesenchymal Stem Cells: Candidate Cells Responsible for Healing Critical-Sized Calvarial Bone Defects (2015)

Postnatal tissue-specific stem/progenitor cells hold great promise to enhance repair of damaged tissues. Many of these cells are retrieved from bone marrow or adipose tissue via invasive procedures. Peripheral blood is an ideal alternative source for the stem/progenitor cells because of its ease of retrieval. We present a coculture system that routinely produces a group of cells from adult peripheral blood. Treatment with these cells enhanced healing of critical-size bone defects in the mouse calvarium, a proof of principle that peripheral blood-derived cells can be used to heal bone defects. From these cells, we isolated a subset of CD45(-) cells with a fibroblastic morphology. The CD45(-) cells were responsible for most of the differentiation-induced calcification activity and were most likely responsible for the enhanced healing process. These CD45(-) fibroblastic cells are plastic-adherent and exhibit a surface marker profile negative for CD34, CD19, CD11b, lineage, and c-kit and positive for stem cell antigen 1, CD73, CD44, CD90.1, CD29, CD105, CD106, and CD140α. Furthermore, these cells exhibited osteogenesis, chondrogenesis, and adipogenesis capabilities. The CD45(-) fibroblastic cells are the first peripheral blood-derived cells that fulfill the criteria of mesenchymal stem cells as defined by the International Society for Cellular Therapy. We have named these cells "blood-derived mesenchymal stem cells."
Influence of the surface roughness on images acquired by flying spot active thermography: Case of the high pressure turbine blades (2012)

High pressure turbine blades undergo heavy thermomechanical constraints which drive initiation and propagation of cracks. These cracks can be difficult to detect with the current control equipment. The aim of this study is to develop an active thermography process called flying spot (scanning laser heating) in the 1-2 μm range to inspect the blades. This work is funded by the French Ministry of Defense, DGA through the PhD scholarship program and the contract 2010.60.018.
Block Copolymers Self-Assembly Allows Obtaining Tunable Micro or Nanoporous Membranes or Depth Filters Based on PMMA; Fabrication Method and Nanostructures (2014)

An environmentally friendly method to produce tunable bulk micro or nanoporous structures is presented. Nano- and micro-porous structures are obtained by gas dissolution foaming using CO2, following the pattern of polymer blends between poly(methylmethacrylate) (PMMA) and a triblock copolymer, namely poly(methylmethacrylate)-co-poly(butyl acrylate)-co-poly(methyl methacrylate) (MAM) blends nanostructuration. Membranes or depth filters can be produced by this method, varying the amount of the triblock copolymer in the blend. Furthermore, main characteristics, such as the average pore size and porosity can be finely tuned by adjusting the process parameters (temperature or pressure) during gas foaming.
Restricted Rotation in Aryl Olefins. I. Preparation and Resolution of β-Chloro-β-(2,4,6-trimethyl-3-bromophenyl)-α-methylacrylic Acid (1940)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRestricted Rotation in Aryl Olefins. I. Preparation and Resolution of β-Chloro-β-(2,4,6-trimethyl-3-bromophenyl)-α-methylacrylic AcidRoger Adams and M. W. MillerCite this: J. Am. Chem. Soc. 1940, 62, 1, 53–56Publication Date (Print):January 1, 1940Publication History Published online1 May 2002Published inissue 1 January 1940https://pubs.acs.org/doi/10.1021/ja01858a011https://doi.org/10.1021/ja01858a011research-articleACS PublicationsRequest reuse permissionsArticle Views300Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Human Coronavirus 229E Papain-Like Proteases Have Overlapping Specificities but Distinct Functions in Viral Replication (2007)

Expression of the exceptionally large RNA genomes of CoVs involves multiple regulatory mechanisms, including extensive proteolytic processing of the large replicase polyproteins, pp1a and pp1ab, by two types of cysteine proteases: the chymotrypsin-like main protease and papain-like accessory proteases (PLpros). Here, we characterized the proteolytic processing of the human coronavirus 229E (HCoV-229E) amino-proximal pp1a/pp1ab region by two paralogous PLpro activities. Reverse-genetics data revealed that replacement of the PL2pro active-site cysteine was lethal. By contrast, the PL1pro activity proved to be dispensable for HCoV-229E virus replication, although reversion of the PL1pro active-site substitution to the wild-type sequence after several passages in cell culture indicated that there was selection pressure to restore the PL1pro activity. Further experiments showed that both PL1pro and PL2pro were able to cleave the nsp1-nsp2 cleavage site, with PL2pro cleaving the site less efficiently. The PL1pro-negative mutant genotype could be stably maintained in cell culture when the nsp1-nsp2 site was replaced by a short autoproteolytic sequence, suggesting that the major driving force for the observed reversion of the PL1pro mutation was the requirement for efficient nsp1-nsp2 cleavage. The data suggest that the two HCoV-229E PLpro paralogs have overlapping substrate specificities but different functions in viral replication. Within the tightly controlled interplay of the two protease activities, PL2pro plays a universal and essential proteolytic role that appears to be assisted by the PL1pro paralog at specific sites. Functional and evolutionary implications of the differential amino-terminal polyprotein-processing pathways among the main CoV lineages are discussed.
Source-oriented topology aggregation with multiple QoS parameters in hierarchical ATM networks (2003)

We investigate the problem of topology aggregation (TA) for scalable, QoS-based routing in ATM networks. TA is the process of summarizing the topological information of a subset of network elements. This summary is flooded throughout the network, and is used by various nodes to determine appropriate routes for connection requests. A key issue in the design of a TA scheme is the appropriate balance between compaction and the corresponding routing performance. The contributions of this paper are twofold. First, we introduce a source-oriented approach to TA, which provides better performance than existing approaches. The intuition behind this approach is that the advertised topology-state information is used by source nodes to determine tentative routes for connection requests. Accordingly, only relevant information to source nodes needs to be advertised. We integrate the source-oriented approach into three new TA schemes that provide different tradeoffs between compaction and accuracy. Second, we extend our source-oriented approach to multi-QoS-based TA. A key issue here is the determination of appropriate values for the multiple QoS parameters that are associated with a logical link. Two new approaches to computing these values are introduced. Extensive simulations are used to evaluate the performance of our proposed schemes.
Sequential Role of Hippocampus and Amygdala, Entorhinal Cortex and Parietal Cortex in Formation and Retrieval of Memory for Inhibitory Avoidance in Rats (1997)

The hippocampus and amygdala, the entorhinal cortex and the parietal cortex participate, in that sequence, both in the formation and in the expression of memory for a step-down inhibitory avoidance task in rats. Bilateral infusion of AP5 or muscimol caused retrograde amnesia when given 0 min after training into both hippocampus and amygdala, when given or 180 min after training into the entorhinal cortex, or when given 180 min after training into the parietal cortex. Therefore, memory formation requires the sequential and integrated activity of all these areas mediated by glutamate NMDA receptors in each case. Pre-test administration of CNQX 1 day after training into hippocampus and amygdala, 1 or 31 days after training in entorhinal cortex, or 1, 31 or 60 days after training in the parietal cortex temporarily blocked retention test performance. Therefore, 1 day after training, all these brain structures are necessary for retrieval; 1 month later, the hippocampus and amygdala are no longer necessary for retrieval but the entorhinal and parietal cortex still are; and 60 days after training only the parietal cortex is needed. In all cases the mechanisms of retrieval require intact glutamate AMPA receptors.
A flexible and modular approach for transmission of digital TV and for interactive services (1995)

This paper describes the system components for modulation and demodulation of digital TV, the compression architecture and the highly flexible interface between the components. The complete system consists of a variety of products which can be combined together by a standardized interface (DVB). The principal of PID (Packed IDentifier) filtering ensures an easy way of multiplexing and remultiplexing of video-, audio- and data streams so that different streams can be guided to different systems components. The transmission data rate is 270 Mbit/s so that about 60 to 70 programms (4 Mbit/s per video) can be transported between the components, e.g. in cable headends. The system also integrates a return path channel for cable and a high sophisticated subscriber management, ordering and billing system for interactive services like video on demand (VOD). Examples of interactive solutions are given and are subject of further technical investigations.
Differential Expression and Sequence Analysis of the Maize Glyceraldehyde-3-Phosphate Dehydrogenase Gene Family (1989)

Douglas A. Russell, Martin M. Sachs, Differential Expression and Sequence Analysis of the Maize Glyceraldehyde-3-Phosphate Dehydrogenase Gene Family, The Plant Cell, Vol. 1, No. 8 (Aug., 1989), pp. 793-803
Image compositing based on virtual cameras (1998)

The virtual camera method presented integrates computer graphics and real-time video processing techniques in a new type of virtual studio. At NHK we developed several image compositing systems based on this method. First we look at the virtual camera method, then some of the systems developed with it. Then we discuss future directions and possibilities not only for image compositing but also for the development of sophisticated systems for editing and producing television programs.
Abrupt drainage basin reorganization following a Pleistocene river capture (2018)

River capture is a dramatic natural process of internal competition through which mountainous landscapes evolve and respond to perturbations in tectonics and climate. River capture may occur when one river network grows at the expense of another, resulting in a victor that steals the neighboring headwaters. While river capture occurs regularly in numerical models, field observations are rare. Here we document a late Pleistocene river capture in the Yimeng Mountains, China that abruptly shifted 25 km<sup>2</sup> of drainage area from one catchment to another. River terraces and imbricated cobbles indicate that the main channel incised 27 m into granitic bedrock within 80 kyr, following the capture event, and upstream propagating knickpoints and waterfalls reversed the flow direction of a major river. Topographic analysis shows that the capture shifted the river basins far from topographic equilibrium, and active divide migration is propagating the effects of the capture throughout the landscape.
Pregnancy in xanthinuria: Demonstration of fetal uric acid production? (1983)

This paper reports biochemical studies in a pregnant xanthinuric female (McKusick 27830) and compares the results with findings in three other xanthinurics studied by us, including a previously unreported female who had a nephrectomy for xanthine stones. The findings of raised levels of uric acid in plasma and urine at presentation in the third trimester of pregnancy, and the subsequent fall to almost undetectable levels 6 weeks post-partum, is regarded as evidence of the extent of fetal uric acid production and clearance by the maternal circulation.
Development of RGD-Based Radiotracers for Tumor Imaging and Therapy: Translating from Bench to Bedside (2013)

The cell adhesion molecule integrin αvβ3 is an important player in the process of angiogenesis. In the last decades, a series of radiolabeled Arg-Gly-Asp (RGD) peptides targeting integrin αvβ3 has been prepared and optimized for positron emission tomography (PET) and single-photon-emission computed tomography (SPECT) imaging of integrin αvβ3 expression. Several promising radiotracers have been tested in clinical trials. In this review, we will introduce strategies that have been used to optimize and accelerate RGD radiotracers towards clinical translation; illustrate RGD-based radiotracers that have been investigated in clinical trials; and discuss the other applications of RGD radiotracers aside from tumor detection.
Multimodal autoencoder: A deep learning approach to filling in missing sensor data and enabling better mood prediction (2017)

To accomplish forecasting of mood in real-world situations, affective computing systems need to collect and learn from multimodal data collected over weeks or months of daily use. Such systems are likely to encounter frequent data loss, e.g. when a phone loses location access, or when a sensor is recharging. Lost data can handicap classifiers trained with all modalities present in the data. This paper describes a new technique for handling missing multimodal data using a specialized denoising autoencoder: the Multimodal Autoencoder (MMAE). Empirical results from over 200 participants and 5500 days of data demonstrate that the MMAE is able to predict the feature values from multiple missing modalities more accurately than reconstruction methods such as principal components analysis (PCA). We discuss several practical benefits of the MMAE's encoding and show that it can provide robust mood prediction even when up to three quarters of the data sources are lost.
Endogenous lipase catalyzed transesterification of olive oil fats. The formation of isomeric and oligomeric triacyleglycerols (2012)

The role of lipase to catalyze hydrolysis and transesterification of triacylglycerols (TAGs) was evaluated in model systems as well as in virgin olive oil. Tandem mass spectrometry was applied in the identification of modified TAGs, ionized by electrospray, formed during the incubation of selected TAGs with mono and di carboxylic acids. The oligomerization of TAGs was observed in authentic olive oil samples and verified in model systems under catalysis exerted by lipase, whose presence in olive oil was already documented. The hydrolytic pathways taken under enzymatic treatment is balanced by the formation of TAG oligomers that should not alter the nutritional value of the aliment.
Chlorosilylamines (1971)

J. E. Drake and N. P. C. Westwood, J. Chem. Soc. A, 1971, 3617 DOI: 10.1039/J19710003617
SUPERHYDROPHOBIC SURFACES PREPARED BY PLASMA FLUORINATION OF LOTUS-LEAF-LIKE AMORPHOUS CARBON FILMS (2006)

Lotus-leaf-like amorphous carbon ( a-C ) films were fabricated on glass and Si substrates by a magnetron sputtering system and fluorinated in carbon tetrafluoride plasma. The fluorinated films ( a-C:F ) had a maximum contact angle (CA) of about 162°, which is much larger than that of the nonfluorinated films (105°). Furthermore, the geometric microstructure and chemical composition of the a-C:F films were investigated by scanning electron microscopy and Fourier transform infrared spectrometry, respectively. The characterization results indicated that the CA on the surfaces of the a-C:F films can be improved remarkably by the plasma-fluorinated process. Such a-C:F films that combine superhydrophobicity with other properties may have many potential applications.
Sick Building Syndrome. III.<i>Stachybotrys chartarum</i> (2000)

Increasingly, physicians are being asked to evaluate patients with putative environmentally associated illnesses. These can include a variety of problems, including infectious illnesses (Legionnaire's disease), chemical exposure in the workplace, and sick building syndromes. The latter has been an issue particularly in asthma because of the association of mold and increased bronchial responsiveness. Recently, attention has been focused on the mold Stachybotrys in human disease. Stachybotrys was first identified more than 60 years ago following an epidemic of stomatitis, rhinitis, conjunctivitis, pancytopenia, neurologic disorders, and death in horses. Since then, Stachybotrys has been identified in several outbreaks of disease in animals. It has also attracted attention as a possible agent in idiopathic pulmonary hemorrhage in infants. Stachybotrys is a relatively uncommon fungus but has been isolated from a variety of sources, including contaminated grains, tobacco, indoor air, insulator foams, and water-damaged buildings with high humidity. This fungus is particularly important because it is one of a series of fungi that produces trichothecenes mycotoxins; these mycotoxins are biologically active and can produce a variety of physiological and pathologic changes in humans and animals, including modulation of inflammation and altered alveolar surfactant phospholipid concentrations. The presence of Stachybotrys in a building does not necessarily imply a cause-and-effect relationship with illness, but should alert physicians and healthcare professionals to do more vigorous environmental testing. Guidelines are presented herein for intervention measures in the maintenance of heating, ventilation, and air-conditioning systems.