gebhart/patrepeval huggingface dataset:
33.2: Spatial Resolution Characteristics of Organic Light‐emitting Diode Displays: A comparative Analysis of MTF for Handheld and Workstation Formats (2013)

Abstract We characterized the spatial resolution of organic light‐emitting diode displays of various sizes and formats including handheld and workstation devices. We observed in some cases significant signal crosstalk between adjacent pixels resulting in degraded resolution characteristics. Handheld displays showed improved resolution characteristics as evidenced by modulation transfer functions.
EMT and EGFR in CTCs cytokeratin negative non-metastatic breast cancer (2014)

Circulating tumor cells (CTCs) are frequently associated with epithelial-mesenchymal transition (EMT).The objective of this study was to detect EMT phenotype through Vimentin (VIM) and Slug expression in cytokeratin (CK)-negative CTCs in non-metastatic breast cancer patients and to determine the importance of EGFR in the EMT phenomenon. In CK-negative CTCs samples, both VIM and Slug markers were co-expressed in the most of patients. Among patients EGFR+, half of them were positive for these EMT markers. Furthermore, after a systemic treatment 68% of patients switched from CK- to CK+ CTCs. In our experimental model we found that activation of EGFR signaling by its ligand on MCF-7 cells is sufficient to increase EMT phenotypes, to inhibit apoptotic events and to induce the loss of CK expression. The simultaneous detection of both EGFR and EMT markers in CTCs may improve prognostic or predictive information in patients with operable breast cancer.
N-Methyl-N-2-propynyl-1-indanamine. A Potent Monoamine Oxidase Inhibitor (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN-Methyl-N-2-propynyl-1-indanamine. A Potent Monoamine Oxidase InhibitorC. F. Huebner, Ellen M. Donoghue, A. J. Plummer, and P. A. FurnessCite this: J. Med. Chem. 1966, 9, 6, 830–832Publication Date (Print):November 1, 1966Publication History Published online1 May 2002Published inissue 1 November 1966https://pubs.acs.org/doi/10.1021/jm00324a009https://doi.org/10.1021/jm00324a009research-articleACS PublicationsRequest reuse permissionsArticle Views211Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Solution and Suspension Plasma Spraying of Nanostructure Coatings (2012)

1. The high energy, high velocity jet generation that includes the torch, power supply, gas supply, and the associated controls; 2. The coating material preparation, i.e. powder manufacturing that controls particle size distribution and morphology, injection by a carrier gas into the high energy gas jet and transformation into a stream of molten droplets;
The Duke of Newcastle, Ecclesiastical Minister, 1724-54 (1934)

Research Article| June 01 1934 The Duke of Newcastle, Ecclesiastical Minister, 1724-54 Donald G. Barnes Donald G. Barnes Search for other works by this author on: This Site PubMed Google Scholar Pacific Historical Review (1934) 3 (2): 164–191. https://doi.org/10.2307/3633377 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Donald G. Barnes; The Duke of Newcastle, Ecclesiastical Minister, 1724-54. Pacific Historical Review 1 June 1934; 3 (2): 164–191. doi: https://doi.org/10.2307/3633377 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentPacific Historical Review Search This content is only available via PDF. Copyright 1934 The Arthur H. Clark Company Article PDF first page preview Close Modal You do not currently have access to this content.
High Performance Liquid Chromatography on Calixarene-Bonded Silica Gels. III. Separations of cis/trans Isomers of Proline-Containing Peptides (1998)

The liquid chromatographic behavior of p-tert-butylcalix[n]arene (n = 4,5,6, and 8) for the separation of cis/trans peptide bond isomers of proline-containing peptides is studied to demonstrate the chromatographic selectivity of calixarene stationary phases. The results are compared with the elution patterns obtained on RP18 and β-cyclodextrin, as well as on a monomeric p-tert-butylphenoxyacetic acid. The chromatographic data are established by rechromatography and 1H-NMR spectroscopy. The results support the assumption that inclusion complexation seems to be a possible separation principle because of the size of the calixarene cavities.
Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling. (1996)

The membrane association of endothelial nitric oxide synthase (eNOS) plays an important role in the biosynthesis of nitric oxide (NO) in vascular endothelium. Previously, we have shown that in cultured endothelial cells and in intact blood vessels, eNOS is found primarily in the perinuclear region of the cells and in discrete regions of the plasma membrane, suggesting trafficking of the protein from the Golgi to specialized plasma membrane structures. Here, we show that eNOS is found in Triton X-100-insoluble membranes prepared from cultured bovine aortic endothelial cells and colocalizes with caveolin, a coat protein of caveolae, in cultured bovine lung microvascular endothelial cells as determined by confocal microscopy. To examine if eNOS is indeed in caveolae, we purified luminal endothelial cell plasma membranes and their caveolae directly from intact, perfused rat lungs. eNOS is found in the luminal plasma membranes and is markedly enriched in the purified caveolae. Because palmitoylation of eNOS does not significantly influence its membrane association, we next examined whether this modification can affect eNOS targeting to caveolae. Wild-type eNOS, but not the palmitoylation mutant form of the enzyme, colocalizes with caveolin on the cell surface in transfected NIH 3T3 cells, demonstrating that palmitoylation of eNOS is necessary for its targeting into caveolae. These data suggest that the subcellular targeting of eNOS to caveolae can restrict NO signaling to specific targets within a limited microenvironment at the cell surface and may influence signal transduction through caveolae.
Irradiation Effects of Excimer Laser Light on Poly(vinylidene fluoride) (PVdF) Film (1998)

Abstract The irradiation effects of intense ultraviolet (UV) light from ArF and KrF excimer lasers on poly(vinylidene fluoride) (PVdF) were studied. The optical absorption spectroscopy made it clear that irradiation with ArF and KrF excimer laser light mainly caused the formation of diene and triene structures, respectively. From the dependence on the laser intensity it was found that ArF and KrF laser-induced reactions proceeded via single-photon and multi-photon processes, respectively. The wavelength dependence was explained by photochemical and photothermal effects of ArF and KrF excimer lasers, respectively. These results indicate that the distinction of the photo-reaction between the two is closely related to the difference in the absorption sites.
Low level RF system design for the PEP-II B factory (2002)

Heavy beam loading in PEP-II has driven the design of the low level RF system to contain feedback loops similar to those used in proton rings. The RF feedback loops control longitudinal coupled-bunch instabilities caused by the beam interaction with the accelerating mode of the RF cavities by reducing the cavity impedance observed by the beam. The RF system employs a modular design housed in a VXI environment and uses the EPICS control system. Modern control system design and signal processing is used throughout the system. This paper describes the RF system topology and the signal processing used to fulfill the system requirements.
A MEMS Floating Element Shear Stress Sensor for Hypersonic Flows (2004)

This report describes the results of a nine-month study to develop a proof of concept, high-bandwidth, high-resolution, silicon micromachined piezoresistive floating element shear-stress sensor for the measurement of unsteady hypersonic flow phenomena. The work focused on three parts: (1) modeling, optimization, and fabrication of a piezoresistive-based micromachined, floating element shear stress sensor, (2) modeling, fabrication, and testing of an optical geometric Moire' interferometry-based floating element sensor, and (3) test facility development and characterization.
A PMR relaxation study of the mode of coordination of cumene hydroperoxide to cobalt and ruthenium carboxylates (1982)

In the present paper, the nature of the coordination CHP (cumen hydroperoxide) to the paramagnetic trinuclear oxygen-containing carboxylate clusters, hexaacetatotriaqua-..mu../sub 3/-oxotri-Ru (III,III,III) (Ru/sub 3/O) and hexaacetatotriacetate-..mu../sub 3/-oxotri-Co (II,III,III) (Co/sub 3/O), was investigated by the NMR relaxation method. The results obtained in this work are in agreement with the postulate that the coordination of a hydroperoxide to a metal atom of a catalyst may occur either through the oxygen atom of the OH group or through the oxygen atom of the OR group.
Production of Hypericin, Pseudohypericin and Flavonoids in Cell Cultures of Various<i>Hypericum</i>Species and their Chemotypes (1996)

Suspension cultures were established from the shoots of sterile germinated seeds of various provenances of seven Hypericum (H.) species in a half strength modified Murashige and Skoog liquid medium. In most strains of H. perforatum (18 provenances) and all strains of H. maculatum (6 provenances) as well as in the cultures of H. tomentosum, H. bithynicum, H. glandulosum and H. balearicum, hypericin and pseudohypericin could be proven, however, in extremely varying amounts. In general, the pseudohypericin content was significantly higher than that of hypericin. The flavonoid patterns, comprising monomeric quercetin derivatives and dimeric apigenin derivatives, varied among strains over a wide range.
Horsepower with Brains: The Design of the CHIRON Free Piston Engine (2000)

<div class="htmlview paragraph">The C<span class="small-caps">HIRON</span> is a hydraulic free piston engine developed by the Dutch companies NOAX and Innas. In the C<span class="small-caps">HIRON</span> the energy of the combustion process is almost directly converted into hydraulic energy. The C<span class="small-caps">HIRON</span> features a direct electronic control of the injection parameters, the flow and the compression ratio. The flow output is controlled by means of Pulse Pause Modulation of the piston frequency. The C<span class="small-caps">HIRON</span> is designed for application in common pressure rail systems. In these systems the hydraulic energy is supplied through a common rail. This paper describes the design of the C<span class="small-caps">HIRON</span>. Special attention will be paid on the specific characteristics of the C<span class="small-caps">HIRON</span> compared to conventional engines and pumps.</div>
Integrated document and workflow management applied to the offer processing of a machine tool company (1995)

Introducing document and workflow management systems causes two main problems:
EasyText: an Operational NLG System (2011)

This paper introduces EasyText, a fully operational NLG System. This application processes numerical data (in tables) in order to generate specific analytical comments of these tables. We start by describing the context of this particular NLG application (communicative goal, user profiles, etc.). We then shortly present the theoretical background which underlies EasyText, before describing its implementation and realization. 1
Endotoxin Tolerance after Severe Injury and Its Regulatory Mechanisms (1996)

Trauma leads to reduced responsiveness of blood monocytes to LPS and a decreased secretion of proinflammatory reacting lymphokines. Because activation of the protein kinase C pathway with PMA or the addition of IFN-gamma significantly increased cytokine response, endotoxin tolerance is not caused by inhibition of protein synthesis, but to disturbances in the signal transduction pathway and its regulating mediators.
A Flow Cytometric Assay of Platelet Activation Marker P-Selectin (CD62P) Distinguishes Heparin-induced Thrombocytopenia (HIT) from HIT with Thrombosis (HITT) (1999)

Heparin induced thrombocytopenia (HIT) is a well-known complication of heparin administration but usually resolves upon discontinuation without sequelae. However, a small proportion of HIT patients develop thrombosis associated with HIT, designated as HITT, which is often life-threatening and may lead to gangrene and amputations. Existing laboratory methods of confirming HIT/HITT do not distinguish between HIT and HITT. We report a flow cytometric assay of platelet activation marker CD62P to distinguish the effects of addition of HIT vs. HITT plasma to normal blood. Briefly, normal whole blood was incubated with platelet-poor plasma from 12 patients with HITT, 30 with HIT, and 65 controls, in presence and absence of heparin, and expression of CD62P was assayed by flow cytometry. When the ratios of fluorescent intensity of CD62P with heparin divided by that without heparin were compared, HITT plasma induced significantly higher ratios than HIT plasma (HITT ratios approximately 2.5 vs. HIT ratios approximately 1.2; p <0.001). Eleven of 12 HITT patients were positive by this test but only 5 of 30 HIT patients were positive (p <0.0005). In a case of HIT with silent thrombosis, this assay gave a positive results prior to clinically evident thrombosis. In conclusion, this method distinguishes HITT from HIT and may be clinically useful in the detection of HITT, allowing early intervention for preventing catastrophic thrombosis.
Characteristic Variation in the Plasma Proteins in Essential Hypertension (1981)

High resolution sodium dodecyl sulfate polyacrylamide gel electrophoresis has disclosed a variation of the plasma proteins in patients with essential hypertension. The presence of this plasma protein anomaly is usually associated with a family history of essential hypertension.
Laser-plasma-based vacuum-ultraviolet light source for tunable single-photon ionization (2007)

Vacuum-UV radiation from Xe jet-target laser-produced plasmas has been produced, spectrally dispersed, and efficiently focused onto a line-shaped interaction volume by adopting an embedded-in-the-chamber spectrograph geometry. Time-resolved 2D Rayleigh light scattering imaging has been carried out for visualizing the gas jet-laser plasma interaction and optimizing the emission intensity and the spectral resolution. We have calibrated the measured photon fluxes, reaching values higher than 10(13) photons/pulse cm(2) nm in the 100-200 nm wavelength range within the first 20 ns from the laser pulse onset. The vacuum-UV light source is predicted to enable sensitive and selective single-photon ionization for time-of-flight mass spectrometry and similar vacuum-UV spectroscopy applications.
Management span of control: how wide is too wide? (2003)

A director at the Saratoga Institute provides some thoughts on the ideal ratio of managers to staff and gives a formula to allow the reader to perform their own caclulations.
High density 256-channel chip integration with flexible parylene pocket (2011)

Current state-of-the-art technologies for retinal prosthetics suffer greatly from complicated IC packaging with high lead count because there is the lack of high density and high lead-count connection. To overcome this challenge, we develop here a packaging technique that utilizes a flexible parylene pocket with metal pads to house a chip for aligned connection. This reported pocket can be designed with the right size to house any IC chip and/or a discrete component. As a demonstration, a 256-channel conduction chip along with an RFID chip have been connected and tested with this technique. The results show that this new technique can be further improved to achieve 10,000 connections within an area of 1 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds (2010)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTNickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen BondsBrad M. Rosen†, Kyle W. Quasdorf‡, Daniella A. Wilson†, Na Zhang†, Ana-Maria Resmerita†, Neil K. Garg*‡, and Virgil Percec*†View Author Information† Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States‡ Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, United States*E-mail: [email protected]; [email protected]Cite this: Chem. Rev. 2011, 111, 3, 1346–1416Publication Date (Web):December 6, 2010Publication History Received12 August 2010Published online6 December 2010Published inissue 9 March 2011https://pubs.acs.org/doi/10.1021/cr100259thttps://doi.org/10.1021/cr100259treview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views38290Altmetric-Citations1216LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anions,Aromatic compounds,Catalysts,Cross coupling reaction,Homocouplings Get e-Alerts
Liquid Filled and Sealed Hard Gelatin Capsules (1986)

A method for sealing liquid filled hard gelatin capsules has been protection against oxidation, have very effective barrier/properties against bad smelling products and have short disintegration times. These properties demonstrate that the liquid filled and sealed hard gelatin capsule offers a real alternative to the soft gelatin capsule.
[Progress in diagnosis and treatment of viral hepatitis in children]. (2021)

Hepatitis B and C virus infections are major global public health problem and economic burden. Most children with vertical infection have asymptomatic hepatitis, but the risk of chronic viral hepatitis and further development of liver cirrhosis or hepatocellular carcinoma is higher. Over the past two to three decades, with the rapid development of detection technology and the continuous research and development of antiviral drugs, great progress has been made in the diagnosis and treatment of viral hepatitis caused by hepatitis B and C infection. However, due to the particularity of its characteristics, it is still necessary to carefully judge and evaluate the diagnosis and antiviral treatment of children. This article focuses on the difficulties in the diagnosis and treatment of viral hepatitis in children, and summarizes its progress.
Germ cell expression of the transcriptional co-repressor TIF1β is required for the maintenance of spermatogenesis in the mouse (2002)

The gene for transcriptional intermediary factor 1beta (TIF1beta) encodes a transcriptional co-repressor known to play essential roles in chromatin remodeling as well as in early embryonic development. During spermatogenesis, TIF1beta is preferentially associated with heterochromatin structures of Sertoli cells and round spermatids, as well as with meiotic chromosomes. Its expression is tightly regulated within spermatocyte and spermatid populations, and it is undetectable in spermatogonia. Spatiotemporally controlled ablation of TIF1beta by using a germ cell lineage-specific CreER(T)/loxP system leads to testicular degeneration. This degeneration is not due to impairment of chromatin remodeling processes during meiosis and spermiogenesis, as TIF1beta-deficient spermatocytes are able to complete their differentiation into spermatozoa. It rather occurs as a consequence of shedding of immature germ cells (spermatocytes and spermatids), and disappearance of stem spermatogonia. These results indicate that TIF1beta has important functions in the homeostasis of the seminiferous epithelium, and probably plays a crucial role in the network of paracrine interactions between germ cell subpopulations and/or Sertoli cells.
Presenile dementia in Down's syndrome (1974)

Light and electron microscopic features in the presenile dementia that occurred in a 54 year old woman with Down9s syndrome were identical to those of Alzheimer9s presenile dementia. In both diseases, senile plaques and Alzheimer9s neurofibrillary tangles fill the cerebral cortex and are scattered through subcortical and brainstem nuclei. Although presenile dementia of Down9s syndrome is ill-defined clinically, the marked histologic changes are so predictably age-related that this condition offers many insights into sequences of aging and degeneration in the human brain.
Cu-catalyzed intramolecular hydroarylation of alkynes (2014)

An efficient Cu-catalyzed intramolecular hydroarylation reaction of alkynes has been developed. The reaction is accomplished under mild conditions and shows good tolerance to both electron-rich and electron-deficient aryl nucleophiles. A series of aryl, heteroaryl, alkyl, and even N-group attached alkynes are all suitable substrates for the intramolecular hydroarylation.
A chopper stabilized biasing circuit suitable for cascaded wheatstone-bridge-like sensors (2005)

Many sensitive devices are based on Wheatstone bridge structures or can be modeled as Wheatstone bridges like Hall effect magnetic sensors. These sensors require a biasing circuit, and many solutions were proposed. However, up to now, none of them gives the opportunity to cascade several sensors, while such a cascade can help in improving the signal-to-noise-ratio (SNR) or in removing some parasitic effects through the direct summing/subtraction of sensing/parasitic effects. The circuit this paper presents is based on an operational transconductance amplifier with n output stages, and allows to cascade n Wheatstone-bridge-like sensors. It is shown that the maximal number of bridges which can be efficiently cascaded is limited by the output resistance of the output stages. Nevertheless, this number remains sufficient in practical cases, easily up to n=10. To remove the 1/f noise coming from the output stages, a chopper stabilization is used. We also establish formulas which allow quick hand calculation of the main parameters of the circuit. A prototype where 10 Hall effect sensors are cascaded is presented as well as experimental results.