gebhart/patrepeval huggingface dataset:
Polyhedral clusters in solids. Electronic structure of pentlandite (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolyhedral clusters in solids. Electronic structure of pentlanditeJeremy K. Burdett and Gordon J. MillerCite this: J. Am. Chem. Soc. 1987, 109, 13, 4081–4091Publication Date (Print):June 1, 1987Publication History Published online1 May 2002Published inissue 1 June 1987https://pubs.acs.org/doi/10.1021/ja00247a039https://doi.org/10.1021/ja00247a039research-articleACS PublicationsRequest reuse permissionsArticle Views432Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Amylin, Food Intake, and Obesity (2002)

Amylin, also known as islet amyloid polypeptide, identified in 1987, is a naturally occurring hormone, released by the beta cells of the pancreas and consists of 37 amino acids. Amylin seems to decrease food intake through both central and peripheral mechanisms and indirectly by slowing gastric emptying. The mean basal amylin concentration is higher in obese than in lean human subjects. The amylin response to oral glucose is also greater in obese subjects, whether or not they have impaired glucose tolerance. The elevated amylin levels in obesity may lead to down-regulation of amylin receptors and lessen the impact of postprandial amylin secretion on satiety and gastric emptying. Amylin administration may overcome resistance at target tissues, delay gastric emptying, and have potential for inducing weight loss in obese individuals.
Identification and control of novel growth inhibitors in fed‐batch cultures of Chinese hamster ovary cells (2017)

Chinese hamster ovary (CHO) cells in culture are known to consume large amounts of nutrients and divert most of them toward byproducts, some of which, including lactate and ammonia, are known to be toxic in nature. Glucose limitation strategies can successfully control lactate accumulation in fed-batch cultures yielding higher peak cell densities and titers. Interestingly, even in such optimized cultures, cell growth slows and eventually stops, indicating the emergence of other factors that negatively affect cell growth. In this study, we employed omics techniques to identify and quantify nine compounds that are intermediates or byproducts of amino acid metabolism, and accumulate in fed-batch cultures. Treatment with these compounds either individually or in a combined fashion resulted in partial or complete cell growth inhibition. Careful control of selected amino acid concentrations between one-half and one millimolar during the growth phase of fed-batch cultures reduced accumulation of the inhibitory metabolites and allowed for higher peak cell densities and increased productivity. Biotechnol. Bioeng. 2017;114: 1779-1790. © 2017 Wiley Periodicals, Inc.
SEAS: a system for early analysis of SoCs (2004)

Systems-on-chip (SoC) continue to be very complex to design and verify, despite extensive component reuse. Although reusable components are predesigned and preverified, when they are assembled in an SoC there is no guarantee that the whole system will behave as expected from a performance, cost and integration point of view. In many cases this is because of faulty early design decisions regarding the architecture, core selection, floorplanning, etc. This paper presents a system for early analysis of SoCs which helps designers make early decisions regarding performance, area, timing and power; and allows them to quickly evaluate cross-domain effects, such as the effect that an architectural decision may have on the performance and chip area.
Capacity of Human Coronary Arteries (1959)

A postmortem study of the capacity of the coronary arteries of 100 human hearts is presented. The volume of Schlesinger's barium sulfate-gelatin injection mass entering the coronary arterial tree under standard conditions was taken as a measure of its capacity. The factors analyzed include the weight of the heart in the normal and diseased state, the cross-sectional dimensions of the main coronary arteries near their origins, and the sex, age, and nutrition of the subjects.
5-Aminosalicylic Acid Enemas in the Maintenance of Remission in Distal Ulcerative Colitis and Proctitis (1987)

A randomized clinical trial of the efficacy and safety of two different dosages of 5-aminosalicylic acid (5-ASA) enemas was carried out in 29 patients who had documented ulcerative colitis involving up to 50cm of distal colon. All patients were in remission or had minimal disease activity (Disease Activity Index [DAI] less than 4) at the time of study entry. The two patient groups were similar in terms of age, sex ratio and disease activity. Further significant reduction in DAI occurred during the first three months of the study. Five patients (two in the 2 g group and three in the 4g group) relapsed over the next six months. There were no significant differences in DAI of the two groups over the six month study period (ANOVA for repeated measures). Six patients dropped out of the study all of whom were in remission when last seen (mean follow-up 3. 3 months). In this preliminary study, 2 g enemas were shown to be as effective as 4 g enemas in maintaining remission in patients with ulcerative colitis confined to the distal colon.
Integrated Optical-Phased Array Nanoantenna System Using a Plasmonic Rotman Lens (2016)

An integrated linear optical-phased array with five switchable beams at a spacing of 15° operating at the standard telecommunication wavelength of 1.55 μm is proposed, and numerically studied. To realize the desired phase shift between adjacent antenna elements, a plasmonic Rotman lens is designed. In order to conduct power into a selected input port, a graphene-based power splitter with switchable output is proposed. The antenna array is composed of six plasmonic nanoantennas designed in compatibility with the feeding plasmonic waveguides. The proposed integrated system can be used for applications such as optical wireless communication, interand intrachip optical interconnects, and low-cost integrated LIDAR systems.
People Detection and Tracking with TOF Sensor (2008)

This paper presents a method to detect, track and count people which pass a confined space using the latest 3D Time-of-Flight (ToF) sensor technology. A slicing algorithm is employed and a novel method is proposed which derives the slicing level based on the probability density function and histogram respectively. It was found that the algorithm, exploiting the data of one sensor only, works very well for normal situations. However, additional information needs to be made available to the system to solve specials cases, such as wheel chairs, push chairs or very closely spaced people.
Mosquito Sugar Feeding and Reproductive Energetics (1995)

Sugar feeding is a fundamental characteristic of mosquito life. Most evidence indicates frequent ingestion by both sexes and all ages of mosquitoes of plant sugar, usually as floral and extrafloral nectar and honeydew. Energetically, sugar and blood are interchangeable; females of some species have evolved independence from one or the other, but most need blood to develop eggs and sugar to survive, to fly, and to enhance reproduction. Mosquitoes' commitment to sugar is further illustrated by a wealth of behavioral, structural, and physiological specializations for finding, feeding on, and processing it. Blood and sugar feeding activities are antagonistic and mutually exclusive, owing to conflicting demands, yet they support the same goals and often share the same activity period. The rules by which females make food-choice decisions have been inadequately explored, and we still lack convincing evidence that sugar availability in nature varies sufficiently to affect mosquito populations.
Oral squamous cell cancer in non-users of tobacco and alcohol (1994)

In a well-defined group of 161 consecutive patients with intra-oral squamous cell carcinoma we found 23 non-users of tobacco and alcohol. The non-users in this prospective study were compared with users of tobacco and alcohol in the study, and to a sex- and age-matched control group drawn at random from the Danish Central Citizenry Registration. The users in the patient group represented a significantly higher number than in the control group. As to non-users, women represented a higher number in the patient group compared with the control group. Among users and non-users differences were found in the location of the primary tumour and in the degree of differentiation of the tumour. Haematological status and liver function parameters were different in the two groups. There was no difference in dental or oral hygiene status or risk occupation among the groups. The stage and the course of the disease (corrected survival) showed only insignificant differences. The non-user group contained especially older women, and only one of them had anaemia.
Biocompatible fluorescent core–shell nanoparticles for ratiometric oxygen sensing (2012)

Ratiometric fluorescent core–shell nanoparticles (NPs) with good biocompatibility are successfully prepared by a one-step reprecipitation–encapsulation method for sensing dissolved oxygen. The particle core comprises the oxygen probe platinum(II) octaethylporphine (PtOEP), the reference dye coumarin 6 (C6) and a third fluorophore dinaphthoylmethane (DNM). Upon single 381 nm excitation, C6 gives oxygen-insensitive referenced green fluorescence via intraparticle FRET from DNM, whilst PtOEP yields highly oxygen-sensitive red phosphorescence with a quenching response of 94%. The fluorescence quenching of the NPs against oxygen follows a linear Stern–Volmer behavior, which is fundamental for practical sensing. Moreover, positively charged poly-L-lysine molecules are in situ self-assembled onto the surface of NPs during synthesis. The resultant core–shell NPs with functional groups exhibit low cytotoxic effects as well as effortless cellular uptake, indicating targeted intracellular oxygen sensing is very promising using the oxygen nanosensors.
Fungal cleavage of thioether bond found in Yperite (1997)

The degradation of thiodiglycol (I) and benzyl sulfide (II) was attempted using Coriolus versicolor and Tyromyces palustris to investigate the potential ability of basidiomycetes to degrade Yperite (bis(2-chloroethyl) sulfide), a mass-produced and stored chemical warfare agent. I was very rapidly degraded by both fungi. The metabolic pathway of II was elucidated, showing that the initial step was the hydrolytic cleavage of the thioether bond to yield benzyl alcohol and benzyl mercaptan. Benzyl alcohol was further oxidized and finally mineralized. Benzyl mercaptan is reversibly converted to benzyl disulfide and also converted to benzyl alcohol. Finally, the effective degradation of bis(2-bromoethyl) sulfide strongly suggests that basidiomycete would be a potential tool for Yperite degradation.
Touchdown General Primer (GP5+/GP6+) PCR and optimized sample DNA concentration support the sensitive detection of human papillomavirus (2005)

Touchdown modification of the GP5+/GP6+ PCR assay enables the detection of HPV undetected under regular assay conditions. The use of standardized DNA quantities in a PCR rather than standard sample volumes containing arbitrary amounts of DNA is supported. A touchdown approach may be beneficial as an analytical test for the re-evaluation of (apparently) HPV negative abnormal cervical cytological or histological samples, and for investigating the association of HPV with disease conditions at diverse organ sites. The clinical utility of a touchdown approach for HPV detection requires further investigation as increased assay analytical sensitivity may not necessarily equate with improved clinical sensitivity or specificity.
Food Safety Regulatory System of Developed Countries and the Implication for China (2010)

The problem of food safety has become a focus in the world. In recent years, because of high frequency of food safety accidents, the problems of food safety have appealed much concern in China. This article introduces the features of the food safety regulation of the developed countries and then offers suggestions and the successful experiences that we should learn from when China is establishing our own food safety regulatory system. Key words: food safety; regulatory system; regulatory mode
Analytical techniques in pharmaceutical analysis: A review (2013)

The development of the pharmaceuticals brought a revolution in human health. These pharmaceuticals would serve their intent only if they are free from impurities and are administered in an appropriate amount. To make drugs serve their purpose various chemical and instrumental methods were developed at regular intervals which are involved in the estimation of drugs. These pharmaceuticals may develop impurities at various stages of their development, transportation and storage which makes the pharmaceutical risky to be administered thus they must be detected and quantitated. For this analytical instrumentation and methods play an important role. This review highlights the role of the analytical instrumentation and the analytical methods in assessing the quality of the drugs. The review highlights a variety of analytical techniques such as titrimetric, chromatographic, spectroscopic, electrophoretic, and electrochemical and their corresponding methods that have been applied in the analysis of pharmaceuticals.
Synthesis, Structures, and Optical Properties of Heteroarene-Fused Dispiro Compounds (2010)

Novel heteroarene-fused dispiro compounds, dispiro[9H-fluorene-9,5'(6'H)-diindeno[1,2-b:2',1'-d]furan-6',9''-[9H]fluorene] (dsp-DIF), dispiro[9H-fluorene-9,5'(6'H)-diindeno[1,2-b:2',1'-d]thiophene-6',9''-[9H]fluorene] (dsp-DIT), and 11-phenyldispiro[9H-fluorene-9,5'(6'H)-diindeno[1,2-b:2',1'-d]pyrrole-6',9''-[9H]fluorene] (dsp-DIP-Ph) have been synthesized. Their structures were unambiguously determined by X-ray crystallography. These three dispiro compounds showed blue fluorescence with moderate quantum yields.
On the numerical stability and mass‐lumping schemes for explicit enriched meshfree methods (2011)

SUMMARY Meshfree methods (MMs) such as the element free Galerkin (EFG)method have gained popularity because of some advantages over other numerical methods such as the finite element method (FEM). A group of problems that have attracted a great deal of attention from the EFG method community includes the treatment of large deformations and dealing with strong discontinuities such as cracks. One efficient solution to model cracks is adding special enrichment functions to the standard shape functions such as extended FEM, within the FEM context, and the cracking particles method, based on EFG method. It is well known that explicit time integration in dynamic applications is conditionally stable. Furthermore, in enriched methods, the critical time step may tend to very small values leading to computationally expensive simulations. In this work, we study the stability of enriched MMs and propose two mass‐lumping strategies. Then we show that the critical time step for enriched MMs based on lumped mass matrices is of the same order as the critical time step of MMs without enrichment. Moreover, we show that, in contrast to extended FEM, even with a consistent mass matrix, the critical time step does not vanish even when the crack directly crosses a node. Copyright © 2011 John Wiley & Sons, Ltd.
40 Gbit/s transimpedance amplifier in SiGe bipolartechnology for the receiver in optical-fibre TDM links (1998)

A transimpedance amplifier for a 40 Gbit/s optical-fibre electrical TDM system has been realised in an advanced SiGe bipolar technology. Despite its high gain (transimpedance of 2 kΩ in the limiting mode) the complete amplifier of the receiver was put on a single chip. Clear output eye diagrams at a constant (limited) output voltage swing of 0.6 Vp-p were measured at 40 Gbit/s.
Localization of cystic fibrosis transmembrane conductance regulator mRNA in the human gastrointestinal tract by in situ hybridization. (1994)

We have used in situ hybridization to localize expression of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in the human gastrointestinal tract and associated organs. The stomach exhibits a low level of CFTR expression throughout gastric mucosa. In the small intestine, expression is relatively high in the mucosal epithelium, with a decreasing gradient of expression along the crypt to tip axis. The cells of the Brunner's glands express high levels of CFTR mRNA. In addition, there is a small subpopulation of highly positive cells scattered along the epithelium in the duodenum and jejunum, but not in the ileum. These cells do not represent endocrine cells, as determined by lack of colocalization with an endocrine-specific marker. The distribution of CFTR mRNA in the colon is similar to the small intestine, with highest level of expression in the epithelial cells at the base of the crypts. In the pancreas, CFTR is expressed at high levels in the small, intercalated ducts and at lower levels in the interlobular ducts. CFTR transcripts are expressed at uniformly high levels in the epithelium of the gallbladder. Throughout the gastrointestinal tract, CFTR expression is increased in mucosal epithelial cells that are near lymph nodules.
Lipid Inflammatory Mediators in Diabetic Vascular Disease (2004)

Type 2 diabetes is associated with significantly accelerated rates of macrovascular complications such as atherosclerosis. Emerging evidence now indicates that atherosclerosis is an inflammatory disease and that certain inflammatory markers may be key predictors of diabetic atherosclerosis. Proinflammatory cytokines and cellular adhesion molecules expressed by vascular and blood cells during stimulation by growth factors and cytokines seem to play major roles in the pathophysiology of atherosclerosis and diabetic vascular complications. However, more recently, data suggest that inflammatory responses can also be elicited by smaller oxidized lipids that are components of atherogenic oxidized low-density lipoprotein or products of phospholipase activation and arachidonic acid metabolism. These include oxidized lipids of the lipoxygenase and cyclooxygenase pathways of arachidonic acid and linoleic acid metabolism. These lipids have potent growth, vasoactive, chemotactic, oxidative, and proinflammatory properties in vascular smooth muscle cells, endothelial cells, and monocytes. Cellular and animal models indicate that these enzymes are induced under diabetic conditions, have proatherogenic effects, and also mediate the actions of growth factors and cytokines. This review highlights the roles of the inflammatory cyclooxygenase and 12/15-lipoxygenase pathways in the pathogenesis of diabetic vascular disease. Evidence suggests that inflammatory responses in the vasculature can be elicited by small oxidized lipids that are components of oxidized low-density lipoprotein or products of the lipoxygenase and cyclooxygenase pathways of arachidonic and linoleic acid metabolism. This review evaluates these inflammatory and proatherogenic pathways in the pathogenesis of diabetic vascular disease.
Fibre-induced drag reduction (2008)

We use direct numerical simulation to study turbulent drag reduction by rigid polymer additives, referred to as fibres. The simulations agree with experimental data from the literature in terms of friction factor dependence on Reynolds number and fibre concentration. An expression for drag reduction is derived by adopting the concept of the elastic layer.
Space Deformations, Surface Deformations and the Opportunities In-Between (2009)

在最近的年里，我们在表面变丑技术见证大兴趣。这是能被归因于开发保存详细的技术的能力的反应。在另一方面，空间变丑技术收到了更少的注意，但是不过，他们比基于表面的技术有许多优点。这篇论文探索变丑的这二条途径的潜力并且讨论机会熔化二可以导致。这篇文章(doi:10.1007/s11390-009-9200-0 ) 的联机版本包含增补材料，它对授权的用户可得到。
Re-use of GaAs substrates for epitaxial lift-off III-V solar cells (2002)

The epitaxial lift-off (ELO) method is in general considered to be very suitable for separation of the thin epilayer from its substrate. The used method is very gentle and hardly affects the substrate. We present further improvements on this method resulting in successful separation of crack free thin films as large as 2" substrates. Re-use of the substrates has been investigated with two dimensional optical step profiling to determine the roughness after the different surface cleaning procedures and after the ELO. Also the quality of epilayers after growing on used substrates is determined. In this paper it is demonstrated that substrates can be used several times without loss of epilayer quality.
Reliability enhancement of bi-stable PUFs in 65nm bulk CMOS (2012)

We demonstrate the efficacy and associated costs of three reliability enhancing techniques for bi-stable PUF designs (SRAM and sense amplifier-based) - directed accelerated aging, multiple evaluations, and activation control. Measured results from a 65nm bulk CMOS full custom PUF testchip demonstrate that these technique are able to reduce the percentage of unreliable bits by up to 40%, 83%, and 71% respectively.
Two-qubit Projective Measurements are Universal for Quantum Computation (2001)

Nielsen [quant-ph/0108020] showed that universal quantum computation is possible given quantum memory and the ability to perform projective measurements on up to 4-qubits. We describe an improved method that requires only 2-qubit measurements, which are both sufficient and necessary. We present a method to partially collapse the $C_k$-hierarchy in the indirect construction of unitary gates [Gottesman and Chuang, Nature, {\bf 402} 309 (1999)], and apply the method to find discrete universal sets of 2-qubit measurements.