gebhart/patrepeval huggingface dataset:
Large-scale Semantic Parsing via Schema Matching and Lexicon Extension (2013)

Supervised training procedures for semantic parsers produce high-quality semantic parsers, but they have difficulty scaling to large databases because of the sheer number of logical constants for which they must see labeled training data. We present a technique for developing semantic parsers for large databases based on a reduction to standard supervised training algorithms, schema matching, and pattern learning. Leveraging techniques from each of these areas, we develop a semantic parser for Freebase that is capable of parsing questions with an F1 that improves by 0.42 over a purely-supervised learning algorithm. 1
Sufficiently Digified (2000)

Essay| December 01 2000 Sufficiently Digified Barbara L. Miller Barbara L. Miller Barbara L. Miller has a Ph.D. in Visual and Cultural Studies from the University of Rochester. Currently, she is an assistant professor in the Art Department at Western Washington University. In her teaching and writing, she combines interests in new technologies and representation. She is presently finishing a manuscript on art, photography,film and new media. Search for other works by this author on: This Site PubMed Google Scholar Afterimage (2000) 28 (3): 6. https://doi.org/10.1525/aft.2000.28.3.6 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Barbara L. Miller; Sufficiently Digified. Afterimage 1 December 2000; 28 (3): 6. doi: https://doi.org/10.1525/aft.2000.28.3.6 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAfterimage Search This content is only available via PDF. © 2000 by The Regents of the University of California2000 Article PDF first page preview Close Modal You do not currently have access to this content.
In Situ Synchrotron X-ray Diffraction Experiments on Electrochemically Deposited ZnO Nanostructures (2008)

We present results of in situ synchrotron X-ray diffraction experiments on electrochemically formed ZnO nanostructured films during their growth on to Au substrates. This allows the evolution of texture to be monitored throughout the deposition process. The results are in good agreement with previous in situ X-ray absorption spectroscopy measurements of growth kinetics and indicate that strong preferred orientation, which is not evident from the microstructure, develops early in the growth process.
In vitro and in vivo properties of human/mouse chimeric monoclonal antibody specific for common acute lymphocytic leukemia antigen. (1990)

A human/mouse chimeric monoclonal antibody specific for a common acute lymphocytic leukemia antigen was efficiently obtained by ligating human heavy-chain enhancer element to the chimeric heavy- and light-chain genes. Cell binding and competitive inhibition assays of both radioiodine and indium-111- (111In) labeled chimeric antibodies demonstrated in vitro immunoreactivity identical with that of the parental murine monoclonal antibodies. The biodistribution of the radiolabeled chimeric antibody in tumor-bearing nude mice was similar to that of the parental murine antibody. Tumor accumulation of radioiodinated parental and chimeric antibodies was lower than that of 111In-labeled antibodies, probably because of dehalogenation of the radioiodinated antibodies. Indium-111-labeled chimeric antibody clearly visualized xenografted tumor. These results suggest that a human/mouse chimeric antibody can be labeled with 111In and radioiodine without the loss of its immunoreactivity, and that chimeric antibody localizes in vivo in the same way as the parental murine antibody.
Interleukin-10 Signaling Blocks Inhibitor of κB Kinase Activity and Nuclear Factor κB DNA Binding (1999)

The transcription factor nuclear factor kappaB (NF-kappaB) coordinates the activation of numerous genes in response to pathogens and proinflammatory cytokines and is, therefore, pivotal in the development of acute and chronic inflammatory diseases. In its inactive state, NF-kappaB is constitutively present in the cytoplasm as a p50-p65 heterodimer bound to its inhibitory protein IkappaB. Proinflammatory cytokines, such as tumor necrosis factor (TNF), activate NF-kappaB by stimulating the activity of the IkappaB kinases (IKKs) which phosphorylate IkappaBalpha on serine residues 32 and 36, targeting it for rapid degradation by the 26 S proteasome. This enables the release and nuclear translocation of the NF-kappaB complex and activation of gene transcription. Interleukin-10 (IL-10) is a pleiotropic cytokine that controls inflammatory processes by suppressing the production of proinflammatory cytokines which are known to be transcriptionally controlled by NF-kappaB. Conflicting data exists on the effects of IL-10 on TNF- and LPS-induced NF-kappaB activity in human monocytes and the molecular mechanisms involved have not been elucidated. In this study, we show that IL-10 functions to block NF-kappaB activity at two levels: 1) through the suppression of IKK activity and 2) through the inhibition of NF-kappaB DNA binding activity. This is the first evidence of an anti-inflammatory protein inhibiting IKK activity and demonstrates that IKK is a logical target for blocking inflammatory diseases.
Large-signal stability-oriented design of boost regulators based on a Lyapunov criterion with nonlinear integral (2002)

Exact nonlinear differential equations of boost pulsewidth modulation converters (either with hard-switching or soft-switching, in continuous and discontinuous conduction mode) are obtained, without using average approximations. An extended system of equations also contains the differential equation of the integrated error between the reference and the output voltage. A positive-definite Lyapunov function is defined, including in its expression a nonlinear integral of type Lurie. Sufficient conditions for the Lyapunov stability of the system are determined. Consequently, constraints on the feedback circuit parameters that assure the large-signal stability of the system are formulated. These constraints relate the parameters of the feedback circuit with the values of the power stage elements, load, switching frequency, steady-state duty-cycle. For different values of the steady-state duty-cycle, graphical boundaries which assure the large-signal stability for all the variation of the load are designed. Simulations and experiments confirm the stability of the design.
Former Glory of the Maritime Silk Road (2013)

Fujian is also called Min. Located in Min-nan (Southern Fujian) is city of Quanzhou, hometown of overseas Chinese, and it was historically referred to as Citong, with its alias being the City of Carp. Quanzhou was one of first 24 famous historic and cultural cities in China. As starting point of Maritime Silk Road in medieval times, Quanzhou played an
The Influence of Conductive Additives and Inter‐Particle Voids in Carbon EDLC Electrodes (2010)

Abstract Through the interpretation of porosity and intrusion data, and correlation to the electrochemical response, this study has confirmed that are not only carbon blacks (CBs) very effective in improving the electrical connectivity of a carbon electrode coating, but they also significantly modify the porosity of the electrode coating and thereby also influence ionic diffusion. CBs are more effective conductive fillers than graphites in EDLC electrodes. The highly branched structure of CBs allows multiple electrical contact points and results in a lower electrode electronic resistance. CBs can decrease inter‐particle porosity (both volume and size) and introduce additional porosity that is characteristic of the type of carbon employed. It is observed that electrode coatings prepared from a carbon slurry have a highly macroporous structure and that electrolyte accessibility to individual activated carbon particles is unlikely to be the limiting factor to accessing capacitance. Electrochemical testing has confirmed the strong relationship between bulk electrode resistance and the accessibility of capacitance at different rates.
Fibrinolysis and angiogenesis in wound healing (1991)

The healing wound offers a clear example of the sequence of events in chronic inflammation leading to repair. Although angiogenesis has an obvious and essential role in this process, it has been little studied. For an angiogenic factor to seem relevant, it would have to be shown to precede the peak of increased vascularity. To define this peak, the vessel content of simple, incised mouse wounds was estimated using morphometry of histological sections, and found to rise to a maximum at days 5 and 6. Total angiogenic activity of aqueous extracts was found to reach a peak at day 3. The detection of such activity on the chick chorioallantoic membrane is very dependent on the preparation technique and the choice of proteinase inhibitors. Previous in vitro work by us using purified material has shown fibrin degradation products to be effective in stimulating angiogenesis. Fibrin degradation products are prominent on immunoblotting from day 3, when macrophages are plentiful, with a similar band pattern to human granulation tissue.
Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant (2014)

HIV-1 derived vectors are among the most efficient for gene transduction in mammalian tissues. As the parent virus, they carry out vector genome insertion into the host cell chromatin. Consequently, their preferential integration in transcribed genes raises several conceptual and safety issues. To address part of these questions, HIV-derived vectors have been engineered to be nonintegrating. This was mainly achieved by mutating HIV-1 integrase at functional hotspots of the enzyme enabling the development of streamlined nuclear DNA circles functional for transgene expression. Few integrase mutant vectors have been successfully tested so far for gene transfer. They are cleared with time in mitotic cells, but stable within nondividing retina cells or neurons. Here, we compared six HIV vectors carrying different integrases, either wild type or with different mutations (D64V, D167H, Q168A, K186Q+Q214L+Q216L, and RRK262-264AAH) shown to modify integrase enzymatic activity, oligomerization, or interaction with key cellular cofactor of HIV DNA integration as LEDGF/p75 or TNPO3. We show that these mutations differently affect the transduction efficiency as well as rates and patterns of integration of HIV-derived vectors suggesting their different processing in the nucleus. Surprisingly and most interestingly, we report that an integrase carrying the D167H substitution improves vector transduction efficiency and integration in both HEK-293T and primary CD34+ cells.
Modulation of Ca2+/calmodulin-dependent protein kinase II activity by acute and chronic morphine administration in rat hippocampus: differential regulation of alpha and beta isoforms. (1999)

Calcium/calmodulin-dependent protein kinase II (CaMK II) has been shown to be involved in the regulation of opioid receptor signaling. The present study showed that acute morphine treatment significantly increased both Ca2+/calmodulin-independent and Ca2+/calmodulin-dependent activities of CaMK II in the rat hippocampus, with little alteration in the protein level of either alpha or beta isoform of CaMK II. However, chronic morphine treatment, by which rats were observed to develop apparent tolerance to morphine, significantly down-regulated both Ca2+/calmodulin-independent and Ca2+/calmodulin-dependent activities of CaMK II and differentially regulated the expression of alpha and beta isoforms of CaMK II at protein and mRNA levels. Application of naloxone or discontinuation of morphine treatment after chronic morphine administration, which induced the withdrawal syndrome of morphine, resulted in the overshoot of CaMK II (at both protein and mRNA levels) and its kinase activity. The phenomena of overshoot were mainly observed in the beta isoform of CaMK II but not in the alpha isoform. The effects of both acute and chronic morphine treatments on CaMK II could be completely abolished by the concomitant application of naloxone, indicating that the effects of morphine were achieved through activation of opioid receptors. Our data demonstrated that both acute and chronic morphine treatments could effectively modulate the activity and the expression of CaMK II in the hippocampus.
Mechanism for radiation resistance of InP solar cells (1988)

Photovoltaic properties of InP solar cells and defect behaviors of InP single crystals irradiated with 1-MeV electrons have been studied in order to clarify the superior radiation resistance of InP solar cells compared to Si and GaAs solar cells. It is confirmed that the excellent radiation tolerance of the InP cells is originated from the room-temperature annealing and minority-carrier injection-enhanced annealing phenomena of major radiation-induced defects in InP. The main defects in InP induced by irradiation at room temperature are thought to be due to a Frenkel pair of phosphorus vacancy and interstitial. They are much more mobile than those in GaAs.
A role for natural antibody in the pathogenesis of leprosy: antibody in nonimmune serum mediates C3 fixation to the Mycobacterium leprae surface and hence phagocytosis by human mononuclear phagocytes (1994)

We have previously determined that complement receptors on human mononuclear phagocytes and complement component C3 in nonimmune serum mediate phagocytosis of the intracellular bacterial pathogen Mycobacterium leprae, the agent of leprosy. We have also determined that C3 fixes selectively to the major surface glycolipid of M. leprae, phenolic glycolipid 1 (PGL-1). In this study, we have explored the role of natural antibody in nonimmune serum in C3 fixation and C1q binding to M. leprae and PGL-1. At serum concentrations within the range at which phagocytosis of M. leprae is maximal, C3 fixation was mediated by both the classical and the alternative complement pathways. At the low end of this serum concentration range (2.5%), C3 fixation was mediated predominantly by the classical pathway. Consistent with a role for both pathways, C3 fixation to M. leprae was enhanced by the addition of either pure C1q to C1q-depleted serum or pure factor B to factor B-depleted serum. C3 fixation to M. leprae was strictly antibody dependent regardless of the serum concentration used. C3 fixation to M. leprae occurred in nonimmune serum but not in agammaglobulinemic serum unless heat-inactivated nonimmune serum or small amounts of pure immunoglobulin G (IgG) or IgM were added. C3 fixation by both the alternative and the classical complement pathways was mediated by antibody, and the antigen-binding portion of the antibody molecule was required. C3, IgG, IgM, and C1q were readily detected on the surface of M. leprae. Consistent with the previously demonstrated exclusive role of the classical complement pathway in C3 fixation to PGL-1, C1q bound to PGL-1 in a dose-dependent fashion; C1q binding was evident in > 1.25% nonimmune serum. C1q binding to PGL-1 was strictly antibody dependent. When PGL-1 was incubated with pure C1q, little or no C1q bound to PGL-1 unless heat-inactivated nonimmune serum or pure IgG or IgM was added. When PGL-1 was incubated in nonimmune serum, C3 bound directly to PGL-1 and not to anti-PGL-1 antibody, since the amount of C3 bound to PGL-1 was not reduced by acid elution of the antibody. However, the amount of C3 bound to PGL-1 was markedly reduced by hydroxylamine treatment, providing evidence for C3 fixation via a covalent ester bond. Nonimmune serum contained antibody to all four major M. leprae surface carbohydrates. Relative to PGL-1, nonimmune serum contained more antibody to the other surface carbohydrates.(ABSTRACT TRUNCATED AT 400 WORDS)
Alpha Transport With Derivatives (1999)

Derivatives can be used to transport the alpha from a manager9s selection of securities to virtually any desired asset class benchmark. The authors demonstrate that, by liberating the security selection return from the asset class return, alpha transport allows investors to find the best opportunities in both asset allocation and security selection. They also show how long-short portfolio construction can further enhance return by allowing managers to pursue the best investments in both “winning” and “losing” securities.
A 54-MHz CMOS programmable video signal processor for HDTV applications (1990)

A 54-MHz CMOS video processor with a systolic architecture suited for two-dimensional symmetric FIR (finite impulse response) filtering is reported. The circuit is a one-dimensional digital filter comprising a control part and an array of eight multiplication-accumulation cells. This processor is capable of handling 32 equivalent multiply-add operations in a sampling period as short as 18 ns. Devices can be cascaded to increase the order of the filter in both dimensions, up to 1024 stages with no truncation errors. It has been developed in a 1.2- mu m CMOS technology, and it dissipates less than 500 mW at a 54-MHz clock frequency.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Sand, jams and jets (2005)

The remarkable properties of granular materials are so familiar that most of us do not even notice them. It is clear, for example, that we cannot walk on water unless the temperature has dropped below freezing. However, we take it for granted that sand will support our weight as if it were a solid, even though it can also be poured like a liquid under the same ambient conditions. From breakfast cereal, sugar and flour to construction materials, mining products and pharmaceuticals, granular media are present everywhere in our daily lives.
P385 Population pharmacokinetic modelling of vedolizumab in patients with ulcerative colitis or Crohn's disease (2014)

Clinical: Therapy & observation S225 age, affected area, duration of illness, total dose of PSL administered 4 and 2 weeks before introduction of TAC, CRP and Hb on admission, CAI before TAC administration, and time required for the blood TAC level to reach the target level, but no significant difference was noted in any item.However, a significant difference was noted in the CAI score at the time when the blood TAC level reached the target level between the clinical remission (8±3.2) and non-remission (12±2.6)groups (p < 0.05).When the interval estimation of the mean CAI score was compared between those on admission and at the time of reaching the target TAC level, the reduction rate was 41.7 55.1% in the clinical remission group and 13.8 37% in the non-remission group.Conclusions: The rate of reduction of the CAI score from that before TAC administration to that at the time of reaching the target blood TAC level may be an important predictor of the effect.
A multiple-partition token ring network (2002)

A token-ring local area network capable of operating in multiple parallel segments which are interconnected via a central switch (called a bridge) is the focus of this study. It is shown that while it is beneficial to operate the network as a single token ring at light loads, the single-ring mode also has a limited channel capacity, and that it is preferable to operate the ring in multiple partitions for heavier loads. In particular, it is found that if the switch processing delay is insignificant compared to the mean packet transmission time, it is preferable to operate the network either as a single large ring or as a star network. An approximate analytical model is used. The results are verified via simulation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Hepatocellular carcinoma and cavernous hemangioma: differentiation with MR imaging. Efficacy of T2 values at 0.35 and 1.5 T. (1988)

Seventy-two patients with hepatocellular carcinoma (hepatoma) and 56 with hemangioma were studied with magnetic resonance (MR) imaging at 0.35 or 1.5 T to evaluate the efficacy of T2 values in differential diagnosis. T2 values were calculated with the two-point method. The mean T2 values of hepatoma and hemangioma were 58.9 msec +/- 8.9 and 101.6 msec +/- 25.8 at 0.35 T and 49.1 msec +/- 9.8 and 85.3 msec +/- 21.2 at 1.5 T. The difference in the T2 values for hepatoma and hemangioma was statistically significant (P less than .001) at both 0.35 and 1.5 T. Fifty-three of 56 lesions (94.6%) at 0.35 T and 86 of 102 lesions (84.3%) at 1.5 T were correctly classified when the T2 borderline between hepatoma and hemangioma was set at 80 msec. All misdiagnosed lesions were hemangioma, and all but one were smaller than 2 cm. However, over 90% of lesions smaller than 2 cm were correctly diagnosed when 70 msec at 0.35 T and 60 msec at 1.5 T were used as borderline T2 values. MR imaging with T2 measurement was very useful for differentiating between hepatoma and hemangioma (including small lesions) at 1.5 T as well as at 0.35 T.
MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A (2004)

Cell cycle exit is required for proper differentiation in most cells and is critical for normal development, tissue homeostasis, and tumor suppression. However, the mechanisms that link cell cycle exit with differentiation remain poorly understood. Here, we show that the master melanocyte differentiation factor, microphthalmia transcription factor (MITF), regulates cell cycle exit by activating the cell cycle inhibitor INK4A, a tumor suppressor that frequently is mutated in melanomas. MITF binds the INK4A promoter, activates p16(Ink4a) mRNA and protein expression, and induces retinoblastoma protein hypophosphorylation, thereby triggering cell cycle arrest. This activation of INK4A was required for efficient melanocyte differentiation. Interestingly, MITF was also required for maintaining INK4A expression in mature melanocytes, creating a selective pressure to escape growth inhibition by inactivating INK4A. These findings demonstrate that INK4A can be regulated by a differentiation factor, establish a mechanistic link between melanocyte differentiation and cell cycle exit, and potentially explain the tissue-specific tendency for INK4A mutations to occur in melanoma.
Subtractive Hybridization and Construction of cDNA Libraries (2003)

Genes that are differentially expressed both in time and space are the basis for how single cells, through the process of embryonic development, give rise to animals with an extraordinary diversity of cell types. As a first step in understanding differential gene expression, many researchers seek to identify those genes whose transcripts are temporally or spatially restricted to particular cells, tissues, or embryonic stages. Although there are a variety of methods suitable for identifying moderately to highly expressed genes, the isolation of the most interesting class of mRNAs, those that are not abundant, but that may be cellor tissue-specific, remains the most difficult task.
The MRCAT insertion device beamline at the Advanced Photon Source (2000)

The Materials Research Collaborative Access Team (MRCAT) beamline 10-ID at the Advanced Photon Source has been in Commissioning since January 1998. This Beamline has been designed as a flexible spectroscopy, scattering, and diffraction facility for the study of materials in situ. Over 70 users have performed experiments at the beamline during this period. Details about the beamline layout, components, performance and configuration for typical experiments will be presented
Synthese des 19-Oxo-3-aza-A-homo-5 β-androstans (1970)

Zur Untersuchung der wesentlichen Reaktionsschritte der Synthese des Cycloneosamandions wurde als Modellsubstanz das 19-Oxo-3-aza-A-homo-5β-androstan, ausgehend vom 3β-Hydroxy-5α- chlor-6β,19-epoxy-androstan-17-on dargestellt. Die spektroskopischen Daten stehen im Einklang mit der erwarteten Struktur.