gebhart/patrepeval huggingface dataset:
One-step purification of Escherichia coli H(+)-ATPase (F0F1) and its reconstitution into liposomes with neurotransmitter transporters. (1991)

About 30% of the protein in the inner membrane of Escherichia coli strain DK8/pBWU13 is H(+)-ATPase (F0F1), and practically homogeneous F0F1 could be obtained by gradient centrifugation after solubilization of these membranes. The recombinant plasmid pBWU13 carries the unc operon for F0F1. When reconstituted into liposomes, F0F1 formed an ATP-dependent proton gradient and membrane potential. Proteoliposomes reconstituted with F0F1 and solubilized transporters from chromaffin granules or synaptic vesicle membranes could transport serotonin, dopamine, and norepinephrine dependent on ATP hydrolysis. F0F1 can be obtained rapidly from DK8/pBWU13, and its reconstitution into liposomes with transporters may be useful for monitoring these transporters during their purification.
Segmental durations in the vicinity of prosodic phrase boundaries (1992)

Numerous studies have indicated that prosodic phrase boundaries may be marked by a variety of acoustic phenomena including segmental lengthening. It has not been established, however, whether this lengthening is restricted to the immediate vicinity of the boundary, or if it extends over some larger region. In this study, segmental lengthening in the vicinity of prosodic boundaries is examined and found to be restricted to the rhyme of the syllable preceding the boundary. By using a normalized measure of segmental lengthening, and by compensating for differences in speaking rate, it is also shown that at least four distinct types of boundaries can be distinguished on the basis of this lengthening.
Cathelicidin Peptide Sheep Myeloid Antimicrobial Peptide-29 Prevents Endotoxin-induced Mortality in Rat Models of Septic Shock (2003)

The present study was designed to investigate the antiendotoxin activity and therapeutic efficacy of sheep myeloid antimicrobial peptide (SMAP)-29, a cathelicidin-derived peptide. The in vitro ability of SMAP-29 to bind LPS from Escherichia coli 0111:B4 was determined using a sensitive limulus chromogenic assay. Two rat models of septic shock were performed: (1) rats were injected intraperitoneally with 1 mg E. coli 0111:B4 LPS and (2) intraabdominal sepsis was induced via cecal ligation and single puncture. All animals were randomized to receive parenterally isotonic sodium chloride solution, 1 mg/kg SMAP-29, 1 mg/kg polymyxin B or 20 mg/kg imipenem. The main outcome measures were: abdominal exudate and plasma bacterial growth, plasma endotoxin and tumor necrosis factor-alpha concentrations, and lethality. The in vitro study showed that SMAP-29 completely inhibited the LPS procoagulant activity at approximately 10 microM peptide concentration. The in vivo experiments showed that all compounds reduced the lethality when compared with control animals. SMAP-29 achieved a substantial decrease in endotoxin and tumor necrosis factor-alpha plasma concentrations when compared with imipenem and saline treatment and exhibited a slightly lower antimicrobial activity than imipenem. No statistically significant differences were noted between SMAP-29 and polymyxin B. SMAP-29, because of its double antiendotoxin and antimicrobial activities, could be an interesting compound for septic shock treatment.
Angina pectoris: a review of current and emerging therapies. (2004)

Angina pectoris is a debilitating indication of the presence of ischemic heart disease that affects millions of Americans. Although a number of pharmacologic treatments are available, the annual number of revascularization surgeries continues to rise in the United States. Other management strategies, such as spinal cord stimulation, enhanced external counterpulsation, metabolic modulators, and gene therapy, are being explored.
Granada medium for detection and identification of group B streptococci (1983)

A new starch serum medium, Granada medium, for isolation and identification of group B streptococci (GBS) anaerobically as red colonies is described. The medium contains 3.8% Proteose Peptone no. 3 (Difco), 15% soluble starch 1252 (Merck), 10% coagulated horse serum, 15 micrograms of trimethoprim per ml, and 0.06 M phosphate buffer (pH 7.8; medium pH 7.4). This medium inhibited fecal flora and at the same time supported growth of GBS. A new pigment-enhancing effect of folate inhibitors on GBS is reported and used in the formulation of the medium. The good selective and differential properties of the Granada medium favor quicker and easier detection of GBS in heavily contaminated specimens. Since the medium is convenient to use and requires only 18 h of incubation to detect and identify GBS, it should be useful in any clinical microbiology laboratory and would assist in the early detection of GBS in clinical specimens.
Evolution of Nanoporosity in Dealloying (2001)

Dealloying is a common corrosion process during which an alloy is "parted" by the selective dissolution of the electrochemically more active elements. This process results in the formation of a nanoporous sponge composed almost entirely of the more noble alloy constituents . Even though this morphology evolution problem has attracted considerable attention, the physics responsible for porosity evolution have remained a mystery . Here we show by experiment, lattice computer simulation, and a continuum model, that nanoporosity is due to an intrinsic dynamical pattern formation process - pores form because the more noble atoms are chemically driven to aggregate into two-dimensional clusters via a spinodal decomposition process at the solid-electrolyte interface. At the same time, the surface area continuously increases due to etching. Together, these processes evolve a characteristic length scale predicted by our continuum model. The applications potential of nanoporous metals is enormous. For instance, the high surface area of nanoporous gold made by dealloying Ag-Au can be chemically tailored, making it suitable for sensor applications, particularly in biomaterials contexts.
Autologous bone marrow transplantation using unfractionated cells cryopreserved in dimethylsulfoxide and hydroxyethyl starch without controlled-rate freezing (1987)

To develop a simplified method of bone marrow (BM) cryopreservation, changes were made in the standard method in three areas: the cryoprotectant, the method of cell freezing, and the storage temperature. Unfractionated BM cells from 60 patients were cryopreserved in 300-mL aliquots in both dimethylsulfoxide (DMSO) and hydroxyethyl starch (HES), a combination known to preserve granulocytes successfully. The cells were frozen without rate-controlled freezing by simple immersion into a -80 degrees C freezer where they remained until the time of reinfusion. The 60 patients underwent 72 autologous transplants after three high-dose chemotherapy regimens: 30 received high-dose carmustine in combination, five received high-dose busulfan and cyclophosphamide, and 37 received high-dose aziridinylbenzoquinone. The BM was infused for more than 30 minutes after rapid thawing at 37 degrees C. The mean post-thaw nucleated cell recovery was 96% +/- 11.6%, and Trypan blue dye exclusion was 82.2% +/- 9.2%. The mean postthaw CFU-GM and BFU-E recoveries were 81.9% +/- 39.0% and 90.5% +/- 41.2%. Complete count recovery occurred in 68 of 72 transplants. Median times to a WBC count greater than 1,000/microL, a granulocyte count greater than 1,000/microL and a platelet count greater than 20,000/microL were 15, 21, and 15 days, respectively. Risk factors for delayed recovery were not found. Unfractionated BM cells can be successfully cryopreserved in the DMSO/HES mixture rapidly and inexpensively, without rate-controlled freezing or storage at liquid nitrogen temperatures.
Double-blind evaluation of miconazole tampons, compared with clotrimazole vaginal tablets, in vaginal candidiasis. (1981)

Fifty-one patients with vaginal candidiasis and positive cultures in Nickerson medium were treated either with two miconazole tampons daily for five days (26 patients, median age 28 years) or with one clotrimazole vaginal tablet daily for six days (25 patients, median age 36 years) in a randomized double-blind trial. Seven days after the end of the treatment, 24 (92%) patients in the miconazole group and 19 (76%) in the clotrimazole group had negative cultures. One month after the end of the treatment, the relapse rate was significantly (P less than 0.05) higher in the clotrimazole group. Symptoms subsided rapidly in both groups. No unwanted effects were reported.
Macromol. Rapid Commun. 7/2016 (2016)

Back Cover: An emulsification-induced homo-helicity strategy is established for the first time, for preparing optically active helical polymer nanoparticles, starting from racemic helical polymers. Further details can be found in the article by B. Zhao, J. Deng, and J. Deng* on page 568.
Formulation of Pesticide Microemulsions (1989)

In an attempt to investigate alternative pesticide delivery systems, a three phase approach for the formulation of pesticide microemulsions was developed. Also described are typical surfactants and solvents that can be used in this formulation work. In addition, an explanation of the use of ternary phase diagrams is included to assist the formulator. The development of a 0.5% Chlorpyrifos pesticide microemulsion is described.
Scented Widgets: Improving Navigation Cues with Embedded Visualizations (2007)

This paper presents scented widgets, graphical user interface controls enhanced with embedded visualizations that facilitate navigation in information spaces. We describe design guidelines for adding visual cues to common user interface widgets such as radio buttons, sliders, and combo boxes and contribute a general software framework for applying scented widgets within applications with minimal modifications to existing source code. We provide a number of example applications and describe a controlled experiment which finds that users exploring unfamiliar data make up to twice as many unique discoveries using widgets imbued with social navigation data. However, these differences equalize as familiarity with the data increases.
In-Stent Neointimal Proliferation Correlates With the Amount of Residual Plaque Burden Outside the Stent (1999)

Late in-stent neointimal proliferation has a direct correlation with the amount of residual plaque burden after coronary stent implantation, supporting the hypothesis that plaque removal before stent implantation may reduce restenosis.
Síndrome do andar superior da cápsula interna. Hemiplegia sensitivo-motora capsular (1944)

Desde Türck (1859) os autores têm se preocupado com a passagem de fibras sensitivas pela cápsula interna. Muitas escolas neurológicas têm estudado a questão não só sob o ponto de vista clínico mas também anatômico e experimental. O autor passa em revista a opinião dos autores franceses (Charcot, Dejerine, Roussy, Long, etc.) baseados na anátomo-clínica; dos ingleses com base na experimentação (Horsley, Beevor, Grünbaum, Sherrington, Oppenheim); suíços (Monakow) e americanos (Grinker) sobre as desordens sensitivas nas lesões da cápsula interna. O autor apresenta dois casos anátomo-clínicos de hemiplegia com perturbações sensitivas devidas a lesões da cápsula interna comprovadas anatomicamente. O tálamo estava indene em ambos os casos. A cápsula interna é um diedro formado pelo encontro de dois planos: o segmento anterior e o segmento posterior. Pela parte mais alta (andar superior) do segmento posterior passam as fibras que saem do tálamo em busca da cortiça parietal (fibras tálamo-parietais), as que descem ao pedúnculo cerebral (fibras piramidais) e as que ficam entre o núcleo lenticular e o tálamo (fibras extra-piramidais). No andar inferior do mesmo segmento passam somente as fibras piramidais. O autor estuda do ponto de vista anátomo-clínico a síndrome talâmica de Dejerine e Roussy, os estados talâmicos (Austregesilo e Colares) e a hemiplegia capsular puramente motora. Mostra a inexistência de alterações sensitivas nas hemiplegias devidas à lesão do andar inferior da cápsula interna posterior. Estuda a síndrome do andar superior da cápsula interna posterior ou hemiplegia sensitivo-motora capsular. Documenta dois casos de hemiplegia sensitivo-motora com o estudo anatômico no qual se viu a lesão do andar superior do braço posterior da cápsula interna e integridade do tálamo. Salienta as diferenças existentes entre a mão talâmica e a capsular e chama a atenção para a contratura em flexão com supinação ou pronação verificadas na última, ao passo que na primeira há extensão dos dedos e movimentos córeo-atetósicos. A hemiplegia das lesões talâmicas é rapidamente regressiva e não hipertônica enquanto que a capsular é duradoura e acompanhada de aumento do tonus. Raramente aparecem dores espontâneas nas hemiplegias capsulares bem como hiperpatia de Foerster ou super-reação de Head, fenômenos muito frequentes na síndrome talâmica.
Three Dimensional Coupled Simulation of Furnaces and Reactor Tubes for the Thermal Cracking of Hydrocarbons (1998)

Thermal cracking of hydrocarbons has gone through a significant evolution over the past 20 years. Improved metallurgical properties together with a better understanding of the chemical aspects have led to new configurations for furnace and reactor, all aiming for high severity cracking. A full 3D CFD model containing transport equations for mass, momentum and energy has been implemented in the software code FLOWSIM, together with the k-epsilon turbulence model. It has been coupled with the appropriate kinetic models (the radical reaction scheme CRACKSIM for the reactor and combustion kinetics for the furnace) and an overall iteration scheme has been developed for a coupled furnace-reactor simulation allowing to simulate industrial units. This approach has been applied for a propane cracking furnace, providing detailed understanding of the transport mechanisms taking place.
Recombinant human relaxin as a cervical ripening agent (1997)

Recombinant human relaxin 1 to 4 mg, administered as an intravaginal gel, has no effect as a cervical ripening agent before induction of labour at term.
Near-infrared spectroscopic localization of intracranial hematomas (1993)

Near-infrared spectroscopy (NIRS) of the cerebral hemispheres, applied transcranially through the intact scalp and skull, was evaluated for its ability to detect the presence of an intracranial hematoma in 46 head-injured patients. In 40 patients intracranial hematomas (22 subdural, 10 epidural, eight intracerebral) were identified on computerized tomography (CT); in all 40 cases, NIRS demonstrated greater absorption of light at 760 nm on the side of the hematoma. The mean difference in optical density (OD) between the hemisphere with the hematoma and the normal hemisphere was 0.99 +/- 0.30 for epidural hematomas, 0.87 +/- 0.31 for subdural hematomas, but only 0.41 +/- 0.11 for intracerebral hematomas. In 36 patients, the asymmetry in OD resolved after surgical evacuation of the hematoma or with spontaneous resorption of the hematoma. Four patients who developed postoperative or delayed hematomas exhibited persistence of the asymmetry in OD. Six patients had only diffuse injuries and exhibited only minor differences in OD between the hemispheres, similar to 10 patients in the control group with no head injury. It appears that NIRS is useful in the initial examination of the head-injured patient, as an adjunct to CT, and in following patients postoperatively in the intensive care unit.
The relationship between microvessel density, proliferative activity and expression of vascular endothelial growth factor-A and its receptors in eutopic endometrium and endometriotic lesions (2006)

Studies were performed to elucidate the possible relationship between microvessel density, proliferative activity and angiogenesis in eutopic endometrium from women with and without endometriosis and peritoneal endometriotic lesions. The question whether changes in these parameters in endometriotic lesions were reflected by the level of vascular endothelial growth factor-A (VEGF-A) in serum and peritoneal fluid was also studied. Biopsy specimens of both eutopic endometrium and peritoneal endometriotic lesions from women with endometriosis (n = 25) as well as eutopic endometrium from women without endometriosis (n = 14) were analysed immunohistochemically regarding microvessel density, proliferative activity, and expression of VEGF-A and its receptors vascular endothelial growth factor receptors 1 and 2 (VEGFR-1 and VEGFR-2) in stroma, glands and blood vessels. The VEGF-A concentration was measured in peritoneal fluid and serum. Secretory phase eutopic endometrium from women with endometriosis had significantly higher microvessel density, expression of VEGF-A in glandular epithelium and VEGFR-2 in endometrial blood vessels than those from women without endometriosis. Endometriotic lesions with high proliferative activity had a higher microvessel density and showed higher vascular expression of VEGFR-2 as well as being accompanied by higher levels of VEGF-A in peritoneal fluid and serum, compared with lesions with low proliferative activity. In conclusion, there seems to be a dysregulation of angiogenic activity in the eutopic endometrium of women with endometriosis and endometriotic lesions with high proliferative activity were accompanied by higher local angiogenic activity and higher levels of VEGF in serum and peritoneal fluid.
INTRODUCTION (2017)

I am very pleased to introduce the 2nd number of Sophia[1] from the series Crossing Borders, Shifting Boundaries, with the theme “Photography and Architecture” coming from our 4th edition of the international conference On the Surface, being the Guest Editor for this number Iñaki Bergera. This international conference has proved to be an important forum for debate and reflection about Photography and Architecture, whose work can be accessed through the platform onthesurface.net and in scopio Editions publications as scopio Magazine, Cityzines, Debates, or the catalogue On the Surface: Public Space and Architectural Images in Debate. SCOPIO Editions had already integrated and given support to several congresses and it is the official publisher of the 4th edition of On the Surface: Photography and Architecture, publishing 3 selected reviewed papers and two articles of invited authors on this 2nd number of Sophia Journal. The 4th edition of this international congress aimed to promote a global critical analysis around the theme of Crossing Borders and Shifting Boundaries, exploring how image is a medium that, on the one hand, can cross boarders and shift boundaries between different subjects and disciplines where image and photography are present in a significant way. On the other hand, in what ways image and photography are used as critical instruments to understand how architecture is transformed, how it reflects different hybrid cultural identities in many countries, regions or places and how all of this interacts with and affects our cities. We believe that this congress has contributed for a growing interest awareness and reflection upon Architecture, Art and Image (AAI) and specifically to Documentary and Artistic Photography in regards to its conception as an instrument to question Architecture, City and Territory. This means, understanding Architecture as an extended discipline and practice with an interest, on one side, in the physical space and its experiences, exploring new spatial forms and architectural codes, and on the other side, on how architecture operates within larger systems: socio-cultural, technical, and historical. Then, likewise understanding the potential of both the documentary and artistic universe of photography for building a critical and innovative view of contemporary and past architecture. As well as believing that the worlds of architecture and photography are enriched if photography is not just focused on objectivating and documenting buildings and spaces, as as a direct emanation from the real, but also on creating a new understanding and reality based on a subjective artistic gaze. [...]
Tor1/Sch9-Regulated Carbon Source Substitution Is as Effective as Calorie Restriction in Life Span Extension (2009)

The effect of calorie restriction (CR) on life span extension, demonstrated in organisms ranging from yeast to mice, may involve the down-regulation of pathways, including Tor, Akt, and Ras. Here, we present data suggesting that yeast Tor1 and Sch9 (a homolog of the mammalian kinases Akt and S6K) is a central component of a network that controls a common set of genes implicated in a metabolic switch from the TCA cycle and respiration to glycolysis and glycerol biosynthesis. During chronological survival, mutants lacking SCH9 depleted extracellular ethanol and reduced stored lipids, but synthesized and released glycerol. Deletion of the glycerol biosynthesis genes GPD1, GPD2, or RHR2, among the most up-regulated in long-lived sch9Delta, tor1Delta, and ras2Delta mutants, was sufficient to reverse chronological life span extension in sch9Delta mutants, suggesting that glycerol production, in addition to the regulation of stress resistance systems, optimizes life span extension. Glycerol, unlike glucose or ethanol, did not adversely affect the life span extension induced by calorie restriction or starvation, suggesting that carbon source substitution may represent an alternative to calorie restriction as a strategy to delay aging.
Unified Approach To The Detection And Classification Of Speckle Texture In Diagnostic Ultrasound (1986)

Second order statistics have been derived for the speckle in diagnostic ultrasound that arises from diffuse (incoherent) scattering in the presence of distributed and organized specular (coherent) scattering. They serve as the basis for a three-dimensional feature space in which tissue textures can be classified. The covariance matrix of the measurements in this space is a generalization of the speckle spot number or sampling concept that arises in the study of signal or lesion detectability.
Sharing and Riding: How the Dockless Bike Sharing Scheme in China Shapes the City (2018)

Over the last three years, the dockless bike sharing scheme has become prevalent in the context of the boom in the sharing economy, the wide use of mobile online payment, the increasing environmental awareness and the inherent market demand. This research takes Beijing as a case study, investigates the users’ characteristics, their behaviour change, and perceptions of dockless bike sharing scheme by the quantitative survey, and then analyzes the reasons behind it and how it has changed the residents’ life in Beijing. This new kind of dockless shared bikes, with great advantages of accessibility, flexibility, efficiency and affordability, helps to solve the ‘last mile’ problem, reduce the travel time, and seems to be very environmentally-friendly and sustainable. However, with the help of interview and document analysis, this research finds that the shared bikes are not the effective alternative for the frequent car-users. Nevertheless, it also has numerous negative consequences such as ‘zombie’ bikes blocking the sidewalks and vandalism to the bikes. The public is also worried about their quality and safety, especially the issues of ‘right of way’. How to coordinate and solve these problems is not only related to the future direction of the dockless bike sharing scheme but also to the vital interests of the general public. Therefore, it is important to emphasize that governments, enterprises, and the public participate in multi-party cooperation and build synergic governance networks to carry forward the advantages and avoid the negative effects of the new bike sharing system.
500 delicious salad recipes [title page] (2025)

500 delicious salads. Appetizer salads, bowls and tossed salads, chicken fish and meat salads, dressings, frozen salads, fruit salads, holiday salads, molded salads, salad garnishes, salad plates, vegetable salads.