gebhart/patrepeval huggingface dataset:
Heuristic for setting up a stack of WDM rings with wavelength reuse (2000)

A heuristic methodology is proposed for the setting up of a stack of wavelength-division-multiplexing (WDM) rings with wavelength reuse when the design traffic exceeds the capacity of a single ring and no wavelength conversion is employed. A ring stack consists of an overlay of rings routed over the same physical route, and it can be setup and dimensioned in a myriad of ways. The design traffic comprises of a set of bidirectional lightpaths or wavelength connections. There exists a tradeoff between the number of nodes and the number of rings required to carry this traffic, and it is demonstrated that both cannot be minimized simultaneously. For certain traffic patterns, we identify stacks requiring the minimum number of nodes or WADM's, which is desirable from a cost point of view, and stacks requiring the minimum number of rings. An algorithm is presented that manipulates the tradeoff phenomenon to produce a spectrum of designs with deterministic composition. We finally conclude by identifying factors that may influence the choice of design.
Identification of streptococci from Greek Kasseri cheese and description of Streptococcus macedonicus sp. nov. (1998)

Taxonomic studies were performed on some Streptococcus-like organisms isolated from naturally fermented Greek Kasseri cheese. By SDS-PAGE analysis of whole-cell proteins the group was found to be quite different from Streptococcus thermophilus. Comparative 16S and 23S rRNA sequence analyses showed that the isolates represent a new species within the genus Streptococcus, where they are most closely related to the Streptococcus bovis cluster. On the basis of these phylogenetic results and some phenotypic differences, a new species, Streptococcus macedonicus, is proposed. The type strain is ACA-DC 206.
Regulation of kinesin expression and type IV collagenase secretion in invasive human prostate PC-3 tumor sublines. (1991)

PC-3 human prostatic tumor sublines have been previously isolated which exhibit striking differences in their invasive and metastatic phenotypes. This work has been extended here to measure and compare the levels of kinesin, a microtubule-dependent translocator molecule, in the PC-3 sublines. Western blots, slot blots, radiolabeling, and immunoprecipitation analysis showed that kinesin was expressed in the highly invasive and metastatic sublines at levels which were elevated above the base-line levels observed in the parent PC-3 cells. In comparison, kinesin was not expressed in detectable amounts in the noninvasive cell lines. The conditioned medium of the metastatic PC-3 sublines contained a heat- and trypsin-sensitive protein which exhibited a dosage-dependent capacity to stimulate increased kinesin expression, type IV collagenase secretion, and invasion of Matrigel by the metastatic sublines. The noninvasive sublines failed to secrete a similar stimulatory factor(s) or respond to the conditioned medium of metastatic sublines. Various growth factors and cytokines tested (platelet-derived growth factor, epidermal growth factor, insulin-like growth factor, formylmethionineleucinephenylalanine) had no significant effect on either kinesin expression or protease secretion and invasion. Pertussis toxin blocked the stimulatory effects of the conditioned medium, but other agents known to interfere with adenylate cyclase pathways (i.e., cholera toxin, forskolin, 8-bromoadenosine) failed to block stimulation. The data show for the first time that kinesin, protease secretion, and the resulting invasion process may be regulated in a coordinated manner by an autocrine factor(s) which activates G-protein-dependent processes.
Identification of a new haemophilia B<sub>M</sub> case produced by a mutation located at the carboxy terminal cleavage site of activation peptide (1991)

We describe a novel point mutation due to C----G transversion at nucleotide 20518 in the exon VI of factor IX gene, resulting in the substitution of glycine (GGG) for arginine (CGG) at position 180 in the polypeptide. This point mutation was found in a patient with a haemophilia BM variant. We designated the altered factor IX produced by this new mutation as factor IXMadrid. This mutation blocks the cleavage site involved in the release of the activation peptide at Arg180-Val181. It also abolishes the Aval site (CTCGGG) in exon VI, which can be directly detected with the enzymatic DNA amplification technique (PCR) and offers the possibility of direct analysis in carrier and prenatal diagnosis in kindreds with this mutation.
A SAR Reduced mm-Wave Beam-Steerable Array Antenna With Dual-Mode Operation for Fully Metal-Covered 5G Cellular Handsets (2018)

In this letter, a specific absorption rate (SAR) reduced 28 GHz beam-steering array antenna with dual-mode operation for a fully metal-covered fifth-generation (5G) cellular handset is proposed. The proposed antenna consists of two subarrays, each of which has eight rotated slot antenna elements, which are arranged on the upper frame and on the part of the back cover of the handset. The subarrays are selected according to the modes by using a switch. The proposed array demonstrates good reflection coefficients in the frequency band ranging from 27.2 to 28.2 GHz and the mutual couplings between antenna elements are less than -11.8 dB. The proposed antenna has good beam-steering properties and a hemispherical beam coverage for a millimeter-wave (mm-wave) 5G cellular handset. The calculated peak SAR values on the head phantom by the proposed structure, for the beam scan angles of 0° and 40°, are 0.53 and 0.88 W/kg, respectively, when the input power of each subarray is 24 dBm.
Invasion and metastasis following orthotopic transplantation of human pancreatic cancer in the nude mouse (1989)

A good experimental model for metastasis of human pancreatic cancer would be a valuable tool for the study of this process, which contributes significantly to morbidity and mortality. Models of experimental metastasis using injection of tumor cells into the portal or systemic circulation bypass some important steps of the metastatic process. We describe invasion and metastasis following orthotopic transplantation of human pancreatic carcinoma into nude mice. Tumor pieces were used as xenografts in this study, and metastases were observed in the regional lymph nodes, liver, lungs, and distant lymph nodes of the animals. Peritoneal implants and ascites were not observed in this study. Orthotopic transplantation of human pancreatic cancer in the nude mouse appears to be a promising model of spontaneous metastasis relevant to clinical reality.
Japanese Encephalitis for a Reference to International Travelers (2007)

Japanese encephalitis (JE) is an inflammatory disease in the central nervous system caused by infection with Japanese encephalitis virus (JEV). JE is a disease with a high fatality rate and endemic and epidemic in East, Southeast, and South Asia. High morbidity is noted in children living in the endemic area. JEV is maintained mainly between vector mosquitoes and pigs in nature. The risk of JE increases as the number of vector mosquitoes increases. The expansion of JEV-endemic area depends on irrigated rice field and pig farming. These environments that are suitable for infectious cycle of JEV exist widely in Asia today. The effective and safe vaccine is available in endemic countries and for international travelers. JE vaccination is strongly recommended to those who visit the JEV-endemic regions, especially in the rainy season.
Pharmacological Studies on Repeated Administration of Drugs. I (1963)

1. 鎮咳薬の耐性および交叉耐性について, 犬, モルモットについて検討した.コデイン, モルヒネ, モルヒネNオキシド, 塩酸プロメタジンはいずれも耐性を生じた. また麻薬性鎮咳薬相互には交叉耐性がみられたが, 麻薬性鎮咳薬と非麻薬性鎮咳薬の間には交叉耐性はみられなかった. モルヒネとそのNオキシドの間には耐性の発生にほとんど差がなかった.2. モルヒネ, コデインを鎮痛薬として用いた場合, いずれも耐性を生ずるとともに交叉耐性がみられた.3. モルヒネを連続投与した動物にコデインを投薬したのち, 投薬を中止するとモルヒネの身体依存は軽減された. また実験開始当時の動物の体重によってモルヒネの体重への影響に大きな差がみられた.
A Model for Data Leakage Detection (2009)

We study the following problem: A data distributor has given sensitive data to a set of supposedly trusted agents (third parties). Some of the data is leaked and found in an unauthorized place (e.g., on the Web or somebody's laptop). The distributor must assess the likelihood that the leaked data came from one or more agents, as opposed to having been independently gathered by other means. We propose data allocation strategies (across the agents) that improve the probability of identifying leakages. These methods do not rely on alterations of the released data (e.g., watermarks). In some cases we can also inject "realistic but fake" data records to further improve our chances of detecting leakage and identifying the guilty party.
ChemInform Abstract: ELECTROREDUCTION OF N‐METHYLSUCCINIMIDE TO N‐METHYLPYRROLIDONE (1979)

Abstract Die Elektroreduktion des Imids (I) zum Pyrrolidon (II) wird optimiert.
Spectral characteristics of an all solid-state frequency-shifted feedback laser (1997)

A laser cavity closed via the first-order diffracted light of an acoustooptic modulator is referred to as a frequency-shifted feedback laser (FSF laser). This laser exhibits outstanding features in its oscillation spectrum. We previously demonstrated the first oscillation of an all solid-state FSF laser, and it turned out experimentally that the oscillation spectrum consists of a continuously chirped comb of frequency components. Furthermore, we have been investigating oscillation dynamics both experimentally and analytically for a better understanding of FSF laser. Here experimental results and analyses on the spectral characteristics of the laser are discussed.
Mercury Toxicity from Industrial Exposure (1960)

Instructor in Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pa.
Comparing the Relative Interfacial Affinity of Soft Colloids With Different Crosslinking Densities in Pickering Emulsions (2018)

Pickering emulsions prepared by various kinds of soft colloids such as the poly(<i>N</i>-isopropylacrylamide) (PNIPAM)-based microgels, have been studied for decades in order to fabricate stimuli-responsive emulsions. It has been generally viewed that the interfacial properties of the microgel monolayers and the emulsion stability are dominated by the softness or deformability of the microgel particles. However, there is still no convenient way to characterize the adsorption/desorption energy of the microgels at the interface although this is an essential topic for microgel-stabilized emulsions. This paper presents a novel method for directly comparing the relative interfacial affinity of microgel particles with comparable size but different crosslinking densities, therefore, different softness at the oil/water interface. Typical micron-sized PNIPAM-based microgels were synthesized and used in this study. With advanced fluorescent labeling techniques, we are capable of distinguishing different kinds of microgels in a Pickering emulsion. During vigorous agitation, particles with higher adsorption energy are more likely to be found at the oil/water interface instead of the loosely adsorbed counterparts. By counting the ratio of interfacial area occupied by two microgels, the interfacial affinity of them can be compared. It is found that interfacial affinity of microgels is not only dependent on the softness but also strongly correlated with the core-shell morphology of the microgels, especially the outmost collapsed polymer layer at the interface. This result is consistent with the interfacial morphology model proposed by other researchers. The understanding of the stabilization of such Pickering emulsions can help us to design and develop responsive Pickering emulsions with better controlled stability.
Nse2, a Component of the Smc5-6 Complex, Is a SUMO Ligase Required for the Response to DNA Damage (2004)

The Schizosaccharomyces pombe SMC proteins Rad18 (Smc6) and Spr18 (Smc5) exist in a high-M(r) complex which also contains the non-SMC proteins Nse1, Nse2, Nse3, and Rad62. The Smc5-6 complex, which is essential for viability, is required for several aspects of DNA metabolism, including recombinational repair and maintenance of the DNA damage checkpoint. We have characterized Nse2 and show here that it is a SUMO ligase. Smc6 (Rad18) and Nse3, but not Smc5 (Spr18) or Nse1, are sumoylated in vitro in an Nse2-dependent manner, and Nse2 is itself autosumoylated, predominantly on the C-terminal part of the protein. Mutations of C195 and H197 in the Nse2 RING-finger-like motif abolish Nse2-dependent sumoylation. nse2.SA mutant cells, in which nse2.C195S-H197A is integrated as the sole copy of nse2, are viable, whereas the deletion of nse2 is lethal. Smc6 (Rad18) is sumoylated in vivo: the sumoylation level is increased upon exposure to DNA damage and is drastically reduced in the nse2.SA strain. Since nse2.SA cells are sensitive to DNA-damaging agents and to exposure to hydroxyurea, this implicates the Nse2-dependent sumoylation activity in DNA damage responses but not in the essential function of the Smc5-6 complex.
Syntheses of Female Sex Pheromone Analogues of the German Cockroach and Their Biological Activity (1976)

Journal Article Syntheses of Female Sex Pheromone Analogues of the German Cockroach and Their Biological Activity Get access Tetsuo Sato, Tetsuo Sato Pesticide Research Institute, College of Agriculture, Kyoto University, Kyoto Search for other works by this author on: Oxford Academic Google Scholar Ritsuo Nishida, Ritsuo Nishida Pesticide Research Institute, College of Agriculture, Kyoto University, Kyoto Search for other works by this author on: Oxford Academic Google Scholar Yasumasa Kuwahara, Yasumasa Kuwahara Pesticide Research Institute, College of Agriculture, Kyoto University, Kyoto Search for other works by this author on: Oxford Academic Google Scholar Hiroshi Fukami, Hiroshi Fukami Pesticide Research Institute, College of Agriculture, Kyoto University, Kyoto Search for other works by this author on: Oxford Academic Google Scholar Shoziro Ishii Shoziro Ishii Pesticide Research Institute, College of Agriculture, Kyoto University, Kyoto Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 40, Issue 2, 1 February 1976, Pages 391–394, https://doi.org/10.1080/00021369.1976.10862040 Published: 01 February 1976 Article history Received: 15 October 1975 Published: 01 February 1976
Thermal Process Maps for Controlling Microstructure in Laser-Based Solid Freeform Fabrication (2003)

The ability to predict and control microstructure in laser deposited materials requires an understanding of the thermal conditions at the onset of solidification. The focus of this work is the development of thermal process maps relating solidification cooling rate and thermal gradient (the key parameters controlling microstructure) to laser deposition process variables (laser power and velocity). The approach employs the well-known Rosenthal solution for a moving point heat source traversing an infinite substrate. Cooling rates and thermal gradients at the onset of solidification are numerically extracted from the Rosenthal solution throughout the depth of the melt pool, and dimensionless process maps are presented for both thin-wall (2-D) and bulky (3- D) geometries. In addition, results for both small-scale (LENSTM) and large-scale (higher power) processes are plotted on solidification maps for predicting grain morphology in Ti-6Al-4V. Although the Rosenthal results neglect temperature-dependent properties and latent heat effects, a comparison with 2-D FEM results over a range of LENSTM process variables suggests that they can provide reasonable estimates of trends in solidification microstructure. The results of this work suggest that changes in process variables could potentially result in a grading of the microstructure (both grain size and morphology) throughout the depth of the deposit, and that the size-scale of the laser deposition process is important.
Aromatic Substitution. VIII.<sup>1</sup> Mechanism of the Nitronium Tetrafluoroborate Nitration of Alkylbenzenes in Tetramethylene Sulfone Solution. Remarks on Certain Aspects of Electrophilic Aromatic Substitution<sup>2</sup> (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAromatic Substitution. VIII.1 Mechanism of the Nitronium Tetrafluoroborate Nitration of Alkylbenzenes in Tetramethylene Sulfone Solution. Remarks on Certain Aspects of Electrophilic Aromatic Substitution2George A. Olah, Stephen J. Kuhn, and Sylvia H. FloodCite this: J. Am. Chem. Soc. 1961, 83, 22, 4571–4580Publication Date (Print):November 1, 1961Publication History Published online1 May 2002Published inissue 1 November 1961https://pubs.acs.org/doi/10.1021/ja01483a017https://doi.org/10.1021/ja01483a017research-articleACS PublicationsRequest reuse permissionsArticle Views1163Altmetric-Citations105LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Feasibility and Clinical Efficacy of In Vivo Adsorption of Isohemagglutinins with Fresh Frozen Plasma (FFP) Infusion in Major ABO-incompatible Allogeneic Stem Cell Transplantation (2005)

Background We evaluated the efficacy and feasibility of performing prolonged donor type fresh frozen plasma (FFP) infusion for the in vivo adsorption of isohemagglutinins (IHGs) in major ABO-incompatible allogeneic stem cell transplantation. Methods Forty-five patients underwent allogeneic stem cell transplantation. Major ABO incompatibility was observed in 23 patients. 18 patients of these 23 patients had IHGs directed towards the donor ABO antigens and they received donor type FFP; in 5 patients, the bone marrow grafts were minor incompatible; in 17 patients, the grafts were compatible. Results The engraftment times of the granulocytes and platelets and the transfusion requirements for red blood cells in the FFP-transfused recipients of the major ABO-incompatible allografts were not different from those of therecipients of ABO-compatible allografts (P＞0.1) and these factors were not different from those for the FFP-treated recipients of the major ABO-incompatible allografts. The median duration of FFP infusion and the number of FFP units were 23.5 days (range 8～39) and 47 units (range 16～78), respectively. The median IgG titers decreased from 1: 64 to 1: 4 over a median of 22.5 days (range 8～36) in the FFP-treated groups, compared with a median of 61 days (range 19～116) in the non-FFP-treated groups. Conclusion The infusion of donor-type FFP with red cell depletion represents a more feasible, effective alternative strategy to achieve in vivo immunoadsorption of IHGs and to prevent late immunohematologic complications.
'Literature' in the Queensland Senior English Syllabus (2006)

Analysis of Queensland Studies Authority's Senior English Syllabus helps to consider each section of the syllabus separately and explore the range of understandings of literature that permeate the syllabus. An attempt is made to show that the syllabus is ambiguous and contradictory, and also to suggest ways in which these contradictions could be reconciled.
The <i>bantam</i> Gene Regulates Drosophila Growth (2002)

We report here the consequences of mutations of a novel locus, named bantam, whose product is involved in the regulation of growth in Drosophila. bantam mutant animals are smaller than wild type, due to a reduction in cell number but not cell size, and do not have significant disruptions in patterning. Conversely, overexpression of the bantam product using the EP element EP(3)3622 causes overgrowth of wing and eye tissue. Overexpression in clones of cells results in an increased rate of cell proliferation and a matched increase in cellular growth rate, such that the resulting tissue is composed of more cells of a size comparable to wild type. These effects are strikingly similar to those associated with alterations in the activity of the cyclinD-cdk4 complex. However, epistasis and genetic interaction analyses indicate that bantam and cyclinD-cdk4 operate independently. Thus, the bantam locus represents a novel regulator of tissue growth.
Clinical aspects of Chlamydia pneumoniae infection. (1995)

This recently recognised member of the genus Chlamydia is one of the most widespread pathogens of man, though up to 90% of infected people have few or no symptoms. Several studies have estimated the population prevalence of antibodies to C. pneumoniae at 40-55% in the northern hemisphere, and over 60% in under-developed countries. The incidence of infections follows a cyclical pattern, with peaks at regular intervals of 2-10 years, but no apparent seasonal periodicity. Nosocomial transmission may be mediated by environmental surfaces as well as aerosols, and immunosuppression, for example by the human immunodeficiency virus, predisposes to infection. Chlamydia pneumoniae causes predominantly atypical pneumonia, often severe in adults, especially the elderly; including 5-10% of community-acquired pneumonia in Scandinavian countries. Serological evidence indicates associations with asthma, bronchitis, exacerbations of chronic airflow obstruction, otitis media and bronchiolitis. Several studies, using both serological and morbid anatomical techniques, also indicate associations with vascular atheroma and ischaemic heart disease, and with acute myocardial infarction. Chronic, latent and recurrent infections have been documented, and it is postulated that, like chronic or recurrent C. trachomatis infections, these may produce disease as a consequence of the host's immunological hypersensitivity. Several techniques are available for serological diagnosis: the technique of choice is micro-immunofluorescence, using fixed whole elementary or reticulate bodies as antigen, but antibody responses are highly variable. Traditional alternatives, antigen detection (by direct immunofluorescence or enzyme immunoassay) and cell culture, have major disadvantages. Polymerase chain reactions have not yet been widely applied to the clinical setting. tetracycline antibiotics, erythromycin and quinolones are not very efficacious in the treatment of C. pneumoniae infection. The azalide antibiotic, azithromycin, and the macrolide, clarithromycin, are active in vitro against C. pneumoniae, and may become treatments of choice. The development of anti-chlamydial vaccines remains an important research goal.
Additive Interactions and Depletion Processes in Fuel Efficient Engine Oils (1997)

<div class="htmlview paragraph">Fuel efficient engine oils containing molybdenum dialkyldithiocarbamate, MoDTC, friction modifiers can lose their ability to reduce friction during service prematurely. Depletion processes involving antioxidant reactions and interactions with other additives play important roles in determining the performance of these formulations. This paper describes results from investigations of the antioxidant reactions of MoDTC alone and in combinations with zinc dialkyldithiophosphates and a phenolic antioxidant. The effect of supplementary ashless antioxidant on retention of friction reducing capability is described.</div>