gebhart/patrepeval huggingface dataset:
Photochemical transformations. 48. The nonconcertedness of nucleofuge loss and anti-aryl migration in photochemical Wagner-Meerwein rearrangements (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemical transformations. 48. The nonconcertedness of nucleofuge loss and anti-aryl migration in photochemical Wagner-Meerwein rearrangementsStanley J. Cristol, Mahfuza B. Ali, and Iyer V. SankarCite this: J. Am. Chem. Soc. 1989, 111, 21, 8207–8211Publication Date (Print):October 1, 1989Publication History Published online1 May 2002Published inissue 1 October 1989https://pubs.acs.org/doi/10.1021/ja00203a022https://doi.org/10.1021/ja00203a022research-articleACS PublicationsRequest reuse permissionsArticle Views194Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Status Epilepticus (1995)

Assistant director of the graduate program in nurse anesthesia at Baylor College of Medicine in Houston, TX.
Organolanthanoid‐Carben‐Addukte (1994)

Kein klassischer Carbenkomplex , wenn auch das C2‐Atom des Heterocyclus sp 2 ‐konfiguriert ist und die Bindungslängen im Carbenliganden alternieren, ist 1 (R= Me, i Pr), denn die Yb‐C‐Bindungslänge entspricht der einer verlängerten Einfachbindung. Dennoch macht 1 eine Substanzklasse für f‐Elemente zugänglich, die bei d‐Elemente große Bedeutung hat. magnified image
Cyclin-Dependent Kinase 6 Phosphorylates NF-κB P65 at Serine 536 and Contributes to the Regulation of Inflammatory Gene Expression (2012)

Nuclear factor kappa-B (NF-kB) activates multiple genes with overlapping roles in cell proliferation, inflammation and cancer. Using an unbiased approach we identified human CDK6 as a novel kinase phosphorylating NF-kB p65 at serine 536. Purified and reconstituted CDK6/cyclin complexes phosphorylated p65 in vitro and in transfected cells. The physiological role of CDK6 for basal as well as cytokine-induced p65 phosphorylation or NF-kB activation was revealed upon RNAimediated suppression of CDK6. Inhibition of CDK6 catalytic activity by PD332991 suppressed activation of NF-kB and TNFinduced gene expression. In complex with a constitutively active viral cyclin CDK6 stimulated NF-kB p65-mediated transcription in a target gene specific manner and this effect was partially dependent on its ability to phosphorylate p65 at serine 536. Tumor formation in thymi and spleens of v-cyclin transgenic mice correlated with increased levels of p65 Ser536 phosphorylation, increased expression of CDK6 and upregulaton of the NF-kB target cyclin D3. These results suggest that aberrant CDK6 expression or activation that is frequently observed in human tumors can contribute through NF-kB to chronic inflammation and neoplasia.
Mechanism and clinical implications of bond formation for two dentin bonding agents. (1989)

The mechanism of dentin bonding remains a subject of conjecture. However, sparse evidence is available to support current specific mechanisms for the various systems. Comprehension of the fundamental processes in bonding would encourage a greater appreciation for the critical procedures that ensure clinical success. An SEM study was conducted to examine the mechanism of bonding for two similar dentin bonding systems, Scotchbond 2 and Gluma. For these systems, experimental results support the formation of a mechanical bond resulting from resin infiltration and polymerization within the dentinal matrix. Effective bonding is dependent upon comprehension of the regimented procedures.
Membrane Technology (2000)

Abstract Membranes have gained an important place in chemical technology and are being used increasingly in a broad range of applications. The key property that is exploited in every application is the ability of a membrane to control the permeation of a chemical species in contact with it. This article provides a general overview of the entire membrane area. After a review of the historical development of membranes, the principal types of membrane are described briefly. The manufacture of the more important types of membrane and the packaging of membranes in modules to exploit their properties are discussed. The principal membrane applications, including microfiltration, ultrafiltration, reverse osmosis, pervaporation, gas separation, and controlled drug delivery are described. The particular focus is on the use of membranes to solve separation problems. More complete descriptions of some of the important specific applications of membranes are given elsewhere.
A compact V-band 2-bit reflection-type MEMS phase shifter (2002)

Air-gap overlay CPW couplers and low-loss series metal-to-metal contact microelectromechanical system (MEMS) switches have been employed to reduce the loss of reflection-type MEMS phase shifters at V-band. Phase shift is obtained by changing the lengths of the open-ended stubs using series MEMS switches. A 2-bit [135] reflection-type MEMS phase shifter showed an average insertion loss of 4 dB with return loss better than 11.7 dB from 50 to 70 GHz. The chip is very compact with a chip size as small as 1.5 mm /spl times/ 2.1 mm.
Progress in the development of vaccines against rumen methanogens (2013)

Vaccination against rumen methanogens offers a practical approach to reduce methane emissions in livestock, particularly ruminants grazing on pasture. Although successful vaccination strategies have been reported for reducing the activity of the rumen-dwelling organism Streptococcus bovis in sheep and S. bovis and Lactobacillus spp. in cattle, earlier approaches using vaccines based on whole methanogen cells to reduce methane production in sheep have produced less promising results. An anti-methanogen vaccine will need to have broad specificity against methanogens commonly found in the rumen and induce antibody in saliva resulting in delivery of sufficiently high levels of antibodies to the rumen to reduce methanogen activity. Our approach has focussed on identifying surface and membrane-associated proteins that are conserved across a range of rumen methanogens. The identification of potential vaccine antigens has been assisted by recent advances in the knowledge of rumen methanogen genomes. Methanogen surface proteins have been shown to be immunogenic in ruminants and vaccination of sheep with these proteins induced specific antibody responses in saliva and rumen contents. Current studies are directed towards identifying key candidate antigens and investigating the level and types of salivary antibodies produced in sheep and cattle vaccinated with methanogen proteins, stability of antibodies in the rumen and their impact on rumen microbial populations. In addition, there is a need to identify adjuvants that stimulate high levels of salivary antibody and are suitable for formulating with protein antigens to produce a low-cost and effective vaccine.
Resolution and synthetic aperture characterization of sparse radar arrays (2003)

The concept of radar satellite constellations, or clusters, for synthetic aperture radar (SAR), moving target indicator (MTI), and other radar modes has been proposed and is currently under research. These constellations form an array that is sparsely populated and irregularly spaced; therefore, traditional matched filtering is inadequate for dealing with the constellation's radiation pattern. To aid in the design, analysis, and signal processing of radar satellite constellations and sparse arrays in general, the characterization of the resolution and ambiguity functions of such systems is investigated. We project the radar's received phase history versus five sensor parameters: time, frequency, and three-dimensional position, into a phase history in terms of two eigensensors that can be interpreted as the dimensions of a two-dimensional synthetic aperture. Then, the synthetic aperture expression is used to derive resolution and the ambiguity function. Simulations are presented to verify the theory.
Automatic retransmission rather than automatic repeat request (2002)

The standard HDLC family of protocols has been designed for low to moderate BERs. But as BER increases frequent losses or corruptions of certain frames will cause extensive timeout recovery. Too many timeouts means low throughput. A new retransmission scheme is presented which depends on the transmitter to automatically initiate retransmission instead of the conventional way where the receiver automatically requests retransmission. The retransmission strategy is based on two ideas: the receiver can report without any restriction its buffer status by using a multiple acknowledgement frame and the transmitter keeps a record of the transmission order in which frames were sent. This new approach significantly reduces the use of timeout recoveries, and hence it gives a higher throughput efficiency than the standard and extended HDLC protocols.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The relationship between allergic rhinitis and bronchial asthma (1999)

Allergic rhinitis and bronchial asthma frequently coexist in the same patients. Many patients with rhinitis alone demonstrate nonspecific bronchial hyperresponsiveness, and prospective studies suggest that nasal allergy may be a predisposing risk factor for developing asthma. A growing body of literature has documented that the treatment of patients with allergic rhinitis may result in improvement of asthma symptoms, airway caliber, and bronchial hyperresponsiveness to methacholine and exercise. Finally, mechanistic studies of airway physiology have demonstrated that nasal disease may influence pulmonary function via both direct and indirect mechanisms. Nasal disease should be considered as a possible concomitant illness in all patients with asthma and treated appropriately when identified.
Health and Safety via Surface Modification of Polyurethanes (2013)

Alkylammonium containing polymers are well known to effect contact kill of pathogenic bacteria. For coatings, alkylammonium function is needed only at the surface and not in the bulk. This paper describes a blend strategy that is “processing friendly” and aims at development of modifiers for conventional coating or molding operations. Specifically, the temporal instability of a polyurethane modifier with a copolyoxetane soft block having trifluoroethoxymethyl (3F) and C12 quaternary (dimethyldodecyl ammonium) side chains was overcome by utilizing a –CF2CF2H (4F) fluorous side chain and increasing the C12 mole fraction (U-4F-C12(0.34)). Characterization of a 2 wt% base polyurethane modified with 2 wt% U-4F-C12(0.34) validated a soft block surface modification model. Biocidal effectiveness (100% kill of spray on challenges of Gram+/- bacteria) was retained after storage for at least a month under ambient conditions of temperature and humidity. This stability was correlated with zeta potential measurements of accessible near surface charge. These results suggest zeta potential measurements hold promise as a physical method for assessing effectiveness of polycation contact kill and polycation stability in contact with aqueous systems.
Unimetal super bases (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUnimetal super basesPaul CaubereCite this: Chem. Rev. 1993, 93, 6, 2317–2334Publication Date (Print):September 1, 1993Publication History Published online1 May 2002Published inissue 1 September 1993https://pubs.acs.org/doi/10.1021/cr00022a012https://doi.org/10.1021/cr00022a012research-articleACS PublicationsRequest reuse permissionsArticle Views1946Altmetric-Citations162LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Importance of the traceability of animals and animal products in epidemiology (2001)

Traceability of animals and animal products has become a priority for governments of the developed countries, due to consumer demand for comprehensive and integrated food safety policies. In addition to analysing the differences between traceback and traceability systems, the authors describe some applications of animal traceback systems and the principal characteristics of an animal identification and registration system. The importance of a traceability system for food-borne risk assessment and management, and the most recent approaches towards a comprehensive and integrated animal health and food safety policy are reported.
Application of a Burkholderia cepacia lipase-immobilized silica monolith to batch and continuous biodiesel production with a stoichiometric mixture of methanol and crude Jatropha oil (2011)

The presence of free fatty acids originally contained in Jatropha oil improved the reaction efficiency of the biodiesel production. A combination of B. cepacia lipase and its immobilization support, n-butyl-substituted silica monolith, was effective in the production of biodiesel. This procedure is easily applicable to the design of a continuous flow-through bioreactor system.
ESTIMATION OF THE RATE OF RELEASE OF ADRENAL 17-HYDROXYCORTI-COSTEROIDS IN THE HUMAN BEING BY THE VENOUS CATHETER TECHNIQUE WITH A METHOD FOR DETERMINING PLASMA 17-HYDROXYCORTICOSTEROIDS 1 (1953)

The importance of the role of the adrenal cortex in protein and carbohydrate metabolism and in adjustments to injury has been well established in experimental animals. Studies of the activity of the adrenal cortex in similar situations in hu- man beings have been handicapped by lack of a direct objective method for estimating the rate of secretion of adrenal cortical hormones in the intact man. Since it seemed possible that the in- travenous catheter technique might be applicable to this problem, attempts were made to estimate the rate of secretion of the adrenal hormones di- rectly by obtaining blood from the left renal vein, proximal to the entrance of the adrenal vein, and multiplying the arterio-venous difference in con- centration of cortical hormones by the renal plasma flow. The method has serious limitations, and, as will be discussed below, is probably not sufficiently accurate to be useful as an experimental clinical tool.
Primary structure of the phage P22 repressor and its gene c2 (1981)

The amino acid sequence of the Salmonella phage P2 repressor and the DNA sequence of its gene c2 have been determined. Sequential Edman degradations on intact P22 repressor and repressor peptides generated by proteolytic and chemical cleavages have been overlapped to give approximately 97% of the complete protein sequence. Additionally, the nucleotide sequence of the P22 c2 repressor gene has been determined by DNA sequencing techniques. The DNA sequence and partial protein sequence are collinear and together define the complete amino acid sequence of P22 repressor. The repressor is a single-chain 216 amino acid polypeptide. Basic residues in the sequence tend to be clustered, and residues 9-20 are highly basic, containing five arginyl and three lysyl residues. The carboxyl-terminal 133 amino acids of the c2 repressor are homologous to the carboxyl-terminal sequence of the coliphage lambda cI repressor. The amino-terminal sequences of these two repressors show little similarity.
Orchard heating effectiveness: Protection against radiation frosts by orchard heaters and by wind machines alone and in combination compared (1958)

The following article is the tenth annual report of progress in studies on orchard frost protection, based on report given at the 15th International Horticultural Congress in Nice, France, April 1958, now at Press.
Intravascular release of intact cellular fibronectin during oxidant-induced injury of the in vitro perfused rabbit lung. (1986)

Fibronectin (Fn) is produced by cells in blood vessels at inflammatory sites in vivo. Fn release into the circulation thus may be a marker for vascular injury. In support of this, we found that oxidant-induced vascular injury of isolated perfused rabbit lungs caused elevated circulating Fn levels. Western blot analysis indicated that Fn released from the injured blood vessels was intact, dimeric, and possessed electrophoretic mobility identical with Fn produced by fibroblasts. Unlike Fn isolated from rabbit plasma, Fn derived from lung perfusate or produced by fibroblasts reacted with antibodies raised to a synthetic peptide containing sequences from the extra type III Fn domain that is transcribed in fibroblasts but not hepatocytes. Vascular injury by protease was also associated with intravascular release of Fn, but with cleavage. Oxidant-induced vascular injury causes release of tissue-derived Fn, which can be distinguished from plasma Fn by its size and content of antigenic determinants of the extra type III domain.
Solar Collector Performance Evaluation with the NASA-Lewis Solar Simulator - Results for an All-Glass-Evacuated-Tubular Selectively-Coated Collector with a Diffuse Reflector (1975)

An evacuated tubular all-glass solar collector was tested in the NASA-Lewis solar simulator for inlet temperatures of 70/sup 0/ to 200/sup 0/F, flux levels of 230 and 345 Btu/(hr)(ft/sup 2/), a coolant flow rate of 7 lb/(hr)(ft/sup 2/), and incident angles of 0/sup 0/, 33/sup 0/, and 52/sup 0/. Test results plotted in a form suggested by analysis indicate a very low heat loss coefficient. The collector shows excellent performance on an all-day performance basis, and also for conditions corresponding to temperatures required in solar Rankine systems and/or for low flux level radiation.
Recent achievements in the management of Raynaud&rsquo;s phenomenon (2010)

Raynaud's phenomenon is a clinical disorder with episodic digital ischemic vasospasm triggered by cold- or emotional-stress. It was first mentioned by Maurice Raynaud in 1862 describing "a local asphyxia of the extremities" and was further divided into primary Raynaud's disease and secondary Raynaud's phenomenon, which is often related to connective tissue diseases, but also physical or chemical strain. Though pathophysiology of Raynaud's phenomenon is still poorly understood, systemic and local vascular effects are most likely to be involved in primary Raynaud's disease. In secondary Raynaud's phenomenon additional abnormalities in vascular structure and function may play the major role. Thus, medical treatment of Raynaud's phenomenon remains unsatisfactory, due to limited understanding of pathophysiological mechanisms. This review addresses current evidence for medical treatment of primary and secondary Raynaud's phenomenon with regard to pathophysiological mechanisms as well as future perspectives.
[Effect of prazosin on human prostatic adenoma tissue]. (1988)

The effect of prazosin on epinephrine-induced contractions of human benign prostatic hyperplasia strips was studied. It was shown that prazosin has a pronounced adrenoblocking activity (EC50 = 5.10(-9) g/ml) but fails to affect strip contractions induced by KCL. It is suggested that prazosin can be used in the treatment of patients suffering from benign prostatic hyperplasia.
Electrick (2017)

Current touch input technologies are best suited for small and flat applications, such as smartphones, tablets and kiosks. In general, they are too expensive to scale to large surfaces, such as walls and furniture, and cannot provide input on objects having irregular and complex geometries, such as tools and toys. We introduce Electrick, a low-cost and versatile sensing technique that enables touch input on a wide variety of objects and surfaces, whether small or large, flat or irregular. This is achieved by using electric field tomography in concert with an electrically conductive material, which can be easily and cheaply added to objects and surfaces. We show that our technique is compatible with commonplace manufacturing methods, such as spray/brush coating, vacuum forming, and casting/molding enabling a wide range of possible uses and outputs. Our technique can also bring touch interactivity to rapidly fabricated objects, including those that are laser cut or 3D printed. Through a series of studies and illustrative example uses, we show that Electrick can enable new interactive opportunities on a diverse set of objects and surfaces that were previously static.
Pro-Carboxypeptidase R is an Acute Phase Protein in the Mouse, Whereas Carboxypeptidase N Is Not (2000)

Carboxypeptidase R (EC 3.4.17.20; CPR) and carboxypeptidase N (EC 3. 4.17.3; CPN) cleave carboxyl-terminal arginine and lysine residues from biologically active peptides such as kinins and anaphylatoxins, resulting in regulation of their biological activity. Human proCPR, also known as thrombin-activatable fibrinolysis inhibitor, plasma pro-carboxypeptidase B, and pro-carboxypeptidase U, is a plasma zymogen activated during coagulation. CPN, however, previously termed kininase I and anaphylatoxin inactivator, is present in a stable active form in plasma. We report here the isolation of mouse proCPR and CPN cDNA clones that can induce their respective enzymatic activities in culture supernatants of transiently transfected cells. Potato carboxypeptidase inhibitor can inhibit carboxypeptidase activity in culture medium of mouse proCPR-transfected cells. The expression of proCPR mRNA in murine liver is greatly enhanced following LPS injection, whereas CPN mRNA expression remains unaffected. Furthermore, the CPR activity in plasma increased 2-fold at 24 h after LPS treatment. Therefore, proCPR can be considered a type of acute phase protein, whereas CPN is not. An increase in CPR activity may facilitate rapid inactivation of inflammatory mediators generated at the site of Gram-negative bacterial infection and may consequently prevent septic shock. In view of the ability of proCPR to also inhibit fibrinolysis, an excess of proCPR induced by LPS may contribute to hypofibrinolysis in patients suffering from disseminated intravascular coagulation caused by sepsis.