gebhart/patrepeval huggingface dataset:
27.12MHz GaN resonant power converter with PCB embedded resonant air core inductors and capacitors (2015)

This paper presents the design and implementation of a 27.12 MHz, 320 W, 170 V to 28 V dc-dc resonant power converter with resonant inductors and capacitors embedded into the Printed Circuit Board (PCB). Operating at 27.12 MHz allows for small value and size resonant passive components to be implemented using traces on or within a PCB. Previous work [1]-[14] has demonstrated various ways of using PCBs to make inductors and capacitors. In this work, we evaluate a design with goals of achieving good power density, good EMI shielding, (relatively) low manufacturing cost, and the potential to operate in harsh environments (e.g. strong external magnetic field). Specifically, the proposed prototype converter consists of four vertically stacked PCBs. Two low cost 3.2 mm thick FR4 PCBs are used to make the air core toroidal inductors, and the resonant capacitors are implemented using two low-dielectric-loss thin Rogers PCBs and located in the middle of the stack. To help reduce leakage fields from inducing eddy current within the EMI shield, each resonant inductor is formed by the series/parallel combination of two vertically aligned opposite wound toroids placed in different PCBs. In this arrangement, the circumferential currents of the two inductors flow in opposite directions to cancel the axial “one turn” inductance. Capacitors are formed by two thin layers of high frequency laminates to minimize loss and avoid capacitive heating in the lossy FR4 material. A prototype dc-dc converter was built to verify the concept and it reaches an efficiency of 73.6%. A simulated loss analysis is also presented.
Advanced Compression and Latency Reduction Techniques Over Data Networks (2015)

Applications and services operating over Internet protocol (IP) networks often suffer from high latency and packet loss rates. These problems are attributed to data congestion resulting from the lack of network resources available to support the demand. The usage of IP networks is not only increasing, but very dynamic as well. In order to alleviate the above-mentioned problems and to maintain a reasonable Quality of Service (QoS) for the end users, two novel adaptive compression techniques are proposed to reduce packets’ payload size. The proposed schemes exploit lossless compression algorithms to perform the compression process on the packets’ payloads and thus decrease the overall net- work congestion. The first adaptive compression scheme utilizes two key network performance indicators as design metrics. These metrics include the varying round-trip time (RTT) and the number of dropped packets. The second compression scheme uses other network information such as the incoming packet rate, intermediate nodes processing rate, average packet waiting time within a queue of an intermediate node, and time required to perform the compression process. The performances of the proposed algorithms are evaluated through Network Simulator 3 (NS3). The simulation results show an improvement in network conditions, such as the number of dropped packets, network latency, and throughput.
Expression, purification, crystallization, and biochemical characterization of a recombinant protein phosphatase. (1993)

A protein phosphatase (PPase) from the bacteriophage lambda was overexpressed in Escherichia coli. The recombinant enzyme was purified to homogeneity yielding approximately 17 mg of enzyme from a single liter of bacterial culture. Biochemical characterization of the enzyme showed that it required Mn2+ or Ni2+ as an activator. The recombinant enzyme was active toward serine, threonine, and tyrosine phosphoproteins and phosphopeptides. Surprisingly, the bacterial histidyl phosphoprotein, NRII, was also dephosphorylated by the lambda-PPase. The lambda-PPase shares a number of kinetic and structural properties with the eukaryotic Ser/Thr phosphatases, suggesting that the lambda-PPase will serve as a good model for structure-function studies. Crystallization of the recombinant purified lambda-PPase yielded monoclinic crystals. The crystals diffract to 4.0 A when exposed to synchrotron x-ray radiation.
CoAdapt: Predictable Behavior for Accuracy-Aware Applications Running on Power-Aware Systems (2014)

We present CoAdapt, a runtime that coordinates accuracy-aware applications, which expose accuracy/performance tradeoffs, with power-aware systems, which manage power/performance tradeoffs. This is a challenging problem because decisions made at one level affect, and often counteract, decisions made at the other, leading to unpredictable behavior. Prior approaches have coordinated application and system, but provide a guarantee in only a single dimension (i.e., just one of performance, power, or accuracy). In contrast, CoAdapt addresses the full performance/power/accuracy problem space with an adaptive runtime control system that guarantees behavior in any two of these dimensions, while optimizing the third. We implement CoAdapt on a Linux/x86 platform and show it predictably stabilizes to the desired behavior, adapts to phases in application workload, and supports dynamic changes to behavioral goals.
Peroxo and Superoxo Complexes of Chromium, Molybdenum, and Tungsten (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPeroxo and Superoxo Complexes of Chromium, Molybdenum, and TungstenMichael H. Dickman and Michael T. PopeCite this: Chem. Rev. 1994, 94, 3, 569–584Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 May 1994https://pubs.acs.org/doi/10.1021/cr00027a002https://doi.org/10.1021/cr00027a002research-articleACS PublicationsRequest reuse permissionsArticle Views4173Altmetric-Citations383LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Noninterference through Secure Multi-execution (2010)

A program is defined to be noninterferent if its outputs cannot be influenced by inputs at a higher security level than their own. Various researchers have demonstrated how this property (or closely related properties) can be achieved through information flow analysis, using either a static analysis (with a type system or otherwise), or using a dynamic monitoring system. We propose an alternative approach, based on a technique we call secure multi-execution. The main idea is to execute a program multiple times, once for each security level, using special rules for I/O operations. Outputs are only produced in the execution linked to their security level. Inputs are replaced by default inputs except in executions linked to their security level or higher. Input side effects are supported by making higher-security-level executions reuse inputs obtained in lower-security-level threads. We show that this approach is interesting from both a theoretical and practical viewpoint. Theoretically, we prove for a simple deterministic language with I/O operations, that this approach guarantees complete soundness (even for the timing and termination covert channels), as well as good precision (identical I/O for terminating runs of termination-sensitively noninterferent programs). On the practical side, we present an experiment implementing secure multi-execution in the mainstream Spidermonkey Javascript engine, exploiting parallelism on a current multi-core computer. Benchmark results of execution time and memory for the Google Chrome v8 Benchmark suite show that the approach is practical for a mainstream browser setting. Certain programs are even executed faster under secure multi-execution than under the standard execution. We discuss challenges and propose possible solutions for implementing the technique in a real browser, in particular handling the DOM tree and browser callback functions. Finally, we discuss how secure multi-execution can be extended to handle language features like exceptions, concurrency or nondeterminism.
Surface modes in plasmonic crystals induced by diffractive coupling of nanoantennas (2009)

Lattice surface modes in two-dimensional plasmonic crystals of metallic nanoantennas are sustained by the diffractive coupling between localized plasmon resonances. We have investigated experimentally the dispersion of these modes by combining variable-angle transmittance and reflectance spectroscopy. Transmittance spectra through plasmonic crystals reveal quality factors for these modes exceeding 150 in the near infrared, 30 times higher than the quality factor associated to localized plasmon resonances. We have derived the characteristic lengths of the lattice surface modes, distinguishing a regime in which the group velocity is reduced while the mode intensity is strongly confined near the nanoantennas and a regime in which the surface mode propagates over several unit cells of the plasmonic crystal.
Long-Term Lithium Therapy for Bipolar Disorder: Systematic Review and Meta-Analysis of Randomized Controlled Trials (2004)

Lithium treatment reduces the risk of relapse in bipolar disorder. The preventive effect is clear for manic episodes, although it is equivocal for depressive episodes.
Positive Darwinian selection after gene duplication in primate ribonuclease genes (1998)

Evolutionary mechanisms of origins of new gene function have been a subject of long-standing debate. Here we report a convincing case in which positive Darwinian selection operated at the molecular level during the evolution of novel function by gene duplication. The genes for eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) in primates belong to the ribonuclease gene family, and the ECP gene, whose product has an anti-pathogen function not displayed by EDN, was generated by duplication of the EDN gene about 31 million years ago. Using inferred nucleotide sequences of ancestral organisms, we showed that the rate of nonsynonymous nucleotide substitution was significantly higher than that of synonymous substitution for the ECP gene. This strongly suggests that positive Darwinian selection operated in the early stage of evolution of the ECP gene. It was also found that the number of arginine residues increased substantially in a short period of evolutionary time after gene duplication, and these amino acid changes probably produced the novel anti-pathogen function of ECP.
The Biomedical Applications of Plasma: A Brief History of the Development of a New Field of Research (2008)

This paper is an essay narrating the recent history of the introduction of the biomedical applications of nonthermal plasmas to the plasma science research community.
Efficient isolation and mapping of rad genes of the fungus Coprinus cinereus using chromosome-specific libraries (1992)

We have constructed cosmid libraries from electrophoretically separated chromosomes of the basidiomycete Coprinus cinereus. These libraries greatly facilitate the isolation of genes by complementation of mutant phenotypes and are particularly useful for map-based cloning strategies. From a library constructed from two co-migrating C.cinereus chromosomes, we isolated a clone that complements the C.cinereus rad9-1 mutation. Examination of this clone showed that it complements both the repair and meiotic defects of this mutant. Restriction fragment length polymorphism mapping using a portion of this clone showed that it maps to the rad9 locus. In addition, a single copy of transforming DNA is sufficient to complement the rad9-1 defects. Thus, we believe we have cloned the rad9 gene itself. We also used a chromosome-specific library and backcrossed isolates to rapidly identify a cosmid clone which is tightly linked to the rad11 locus and is therefore a suitable starting point for a chromosome walk. These rapid methods of gene mapping and isolation should be applicable to any organism with separable chromosomes.
Integrated real‐time Raman system for clinical <i>in vivo</i> skin analysis (2008)

In vivo real-time Raman can be a very promising research and practical technique for skin evaluation.
Symplekin, a novel type of tight junction plaque protein. (1996)

Using a monoclonal antibody we have identified and cDNA-cloned a novel type of protein localized, by light and electron microscopy, to the plaque associated with the cytoplasmic face of the tight junction-containing zone (zonula occludens) of polar epithelial cells and of Sertoli cells of testis, but absent from the junctions of vascular endothelia. The approximately 3.7-kb mRNA encodes a polypeptide of 1142 amino acids (calculated molecular weight 126.5 kD, pI 6.25), for which the name "symplekin" (from Greek sigma upsilon mu pi lambda epsilon kappa epsilon iota, nu, to tie together, to weave, to be intertwined) is proposed. However, both the mRNA and the protein can also be detected in a wide range of cell types that do not form tight junctions or are even completely devoid of any stable cell contacts. Careful analyses have revealed that the protein occurs in all these diverse cells in the nucleoplasm, and only in those cells forming tight junctions is it recruited, partly but specifically, to the plaque structure of the zonula occludens. We discuss symplekin as a representative of a group of dual residence proteins which occur and probably function in the nucleus as well as in the plaques exclusive for either tight junctions, adherens junctions, or desmosomes.
Trehalose covalently conjugated to bovine serum albumin (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTrehalose covalently conjugated to bovine serum albuminWalter J. Gensler and Iftekhar AlamCite this: J. Org. Chem. 1977, 42, 1, 130–135Publication Date (Print):January 1, 1977Publication History Published online1 May 2002Published inissue 1 January 1977https://pubs.acs.org/doi/10.1021/jo00421a026https://doi.org/10.1021/jo00421a026research-articleACS PublicationsRequest reuse permissionsArticle Views218Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Microbial Inhabitants of Humans: Their Ecology and Role in Health and Disease (2004)

This advanced textbook provides a unique overview of the microbial communities (normal indigenous microbiota) inhabiting those regions of the human body that are exposed to the external environment, including the skin, eyes, oral cavity and the respiratory, urinary, reproductive and gastrointestinal tracts. In order to understand why particular organisms are able to colonise an anatomical region and why the resulting microbial community has a particular composition, an ecological approach is essential. Consequently, the key anatomical and physiological characteristics of each body site are described throughout the book. The crucial roles of the indigenous microbiota in protecting against exogenous pathogens, regulating the development of our immune system and mucosae, and providing nutrients are also discussed. The involvement of these organisms in infections of healthy and debilitated individuals are discussed throughout and methods of manipulating the composition of the indigenous microbiota for the benefit of human health are also described
Further investigation on the antiinflammatory properties of adolapin--bee venom polypeptide. (1985)

Adolapin is a basic polypeptide (M. W. 11500) isolated from bee venom. It showed marked antiinflammatory and analgetic properties and inhibited cyclooxygenase. It was found that adolapin inhibited also the activity of bee venom phospholipase A2 (7 nmole/ml producing about 80% inhibition of 2.5 nmole/ml phospholipase). In addition it inhibited the lipoxygenase from human platelets (4.5 nmole/ml inhibited about 80% of the activity of 0.8 mg protein/ml). Adolapin (20 micrograms/kg) caused an elevation of c-GMP level in rat spleen and brain as well as a decrease of c-AMP in rat spleen. Adolapin was tested by the "tail flick" method which allowed the demonstration of its analgetic action. The partial inhibition of the analgetic effect of adolapin induced by naloxon, proved the participation of a central mechanism of action. Similar to other nonsteroid analgetics, adolapin displayed antipyretic effect (40 micrograms/kg caused an inhibition of the mean temperature rise about 62%.
Morphological and phase stability of nickel–germanosilicide on Si1−xGex under thermal stress (2002)

Continuous and uniform Ni(Si,Ge) layers are formed on polycrystalline Si and Si0.42Ge0.58 substrate films at 500 °C by rapid thermal processing. The germanosilicide is identified as NiSi0.42Ge0.58, i.e., with the same Si-to-Ge ratio as in the substrate. The NiSi0.42Ge0.58 layer has agglomerated at 600 °C. This is accompanied by a diffusion of Ge out from the germanosilicide grains and the growth of a Ge-rich SiGe region in their close vicinity. These changes cause a slight variation in the atomic composition of Ni(Si,Ge) detectable for individual grains by means of energy dispersive spectroscopy. Above 600 °C, substantial outdiffusion of Ge from the Ni(Si,Ge) grains occurs concurrently with the migration of the grains into the substrate film away from the surface area leaving a Ge-rich SiGe region behind. These observations can be understood with reference to calculated Ni–Si–Ge ternary phase diagrams with and without the inclusion of NiSi2. When Ge is present, the Ni-based self-aligned silicide process presents a robust technique with respect to device applications.
L/sub ∞/-constrained high-fidelity image compression via adaptive context modeling (2002)

We study high-fidelity image compression with a given tight bound on the maximum error magnitude. We propose some practical adaptive context modeling techniques to correct prediction biases caused by quantizing prediction residues, a problem common to the current DPCM like predictive nearly-lossless image coders. By incorporating the proposed techniques into the nearly-lossless version of CALIC, we were able to increase its PSNR by 1 dB or more and/or reduce its bit rate by ten per cent or more. More encouragingly, at bit rates around 1.25 bpp our method obtained competitive PSNR results against the best wavelet coders, while obtaining much smaller maximum error magnitude.
A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect* (1997)

Bispectral analysis can be used as a measure of the EEG effects of anesthetic drugs.
A survey of seroprevalence of human papillomavirus types 16, 18 and 33 among children (1999)

The importance and natural history of HPV infections in childhood is incompletely understood. We performed a survey for presence of serum antibodies to HPV capsids among 1031 children aged 0 to 13 years, resident in Stockholm, Sweden. The HPV seroprevalence among these children was 3.0% for HPV16, 0.6% for HPV18 and 2.7% for HPV33. By comparison, among simultaneously analyzed positive control panels comprising women with CIN or healthy women with type-specific cervical HPV DNA, seroprevalence of HPV 16, 18 and 33 was 69%, 58% and 63% respectively. The results suggest that HPV infection in childhood is not common. Int. J. Cancer 80:489–493, 1999. © 1999 Wiley-Liss, Inc.
Hydrolysis of Double-Stranded and Single-Stranded RNA in Hairpin Structures by the Copper(II) Macrocycle Cu([9]aneN<sub>3</sub>)Cl<sub>2</sub> (1997)

A copper(II) macrocycle functions as an artificial ribonuclease. Cu([9]aneN3)Cl2 hydrolyzes both a 20-base RNA hairpin oligonucleotide and a 31-base sequence of TAR, an RNA sequence found in HIV. The cleavage reaction does not depend on interactions with specific nucleotide bases, and both single-stranded and double-stranded regions of the RNA are cleaved. Moreover, the cleavage of RNA by Cu([9]aneN3)Cl2 proceeds via a hydrolytic mechanism.
THE COMPLETE N-ALKYLATION OF 1,4-DIAMINO-2,5-DIBROMOBENZENE AND OF 1,4-DIAMINO-2,5-DIMETHOXYBENZENE (1969)

(1969). THE COMPLETE N-ALKYLATION OF 1,4-DIAMINO-2,5-DIBROMOBENZENE AND OF 1,4-DIAMINO-2,5-DIMETHOXYBENZENE. Organic Preparations and Procedures: Vol. 1, No. 4, pp. 287-303.
AIScale — A coarse grained reconfigurable CNN hardware accelerator (2017)

In this paper we propose a novel CNN hardware accelerator, called AlScale, capable of accelerating convolutional, pooling, fully-connected and adding CNN layers. In contrast to most existing solutions, AIScale offers a complete solution to the full CNN acceleration. AIScale is designed as a coarse-grained reconfigurable architecture, which uses rapid, dynamic reconfiguration during the CNN layer processing. Furthermore, a novel algorithm for mapping computations to the available computing resources enables AIScale to achieve higher utilization ratios than some of the previously proposed solutions. Results of the experiments indicate that the AIScale architecture is 1.16 to 2.73 times faster and consumes from 25% to 45% less energy on DRAM data transfers than the previously proposed MIT's Eyeriss CNN accelerator while using an identical number of computing units and having almost identical on-chip RAM memory size.