gebhart/patrepeval huggingface dataset:
ANTI-PEROVSKITE SOLID ELECTROLYTE COMPOSITIONS / COMPOSITIONS D'ÉLECTROLYTE SOLIDE ANTIPÉROVSKITE (2012)

If confirmed in larger series, fenoldopam may become an important addition to supportive care to reduce ischemic damage in STEC-HUS and improve long-term outcomes.
CENSORSHIP IN NEW ZEALAND: THE POLICY CHALLENGES OF NEW TECHNOLOGY (2002)

Recent advances in technology have created a range of challenges for those involved in the classification and censorship system in New Zealand. The rapid growth in Internet use, the introduction of DVDs and the availability of low-cost digital recording technology have raised policy and operational problems that did not exist when New Zealand’s current censorship laws were enacted. This paper examines the effects of some of these changes and makes recommendations to address them.
Potential building blocks for molecular ferromagnets: [Mn12O12(O2CPh)16(H2O)4] with a S = 14 ground state (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPotential building blocks for molecular ferromagnets: [Mn12O12(O2CPh)16(H2O)4] with a S = 14 ground statePeter D. W. Boyd, Qiaoying. Li, John B. Vincent, Kirsten. Folting, Hsiu Rong. Chang, William E. Streib, John C. Huffman, George. Christou, and David N. HendricksonCite this: J. Am. Chem. Soc. 1988, 110, 25, 8537–8539Publication Date (Print):December 1, 1988Publication History Published online1 May 2002Published inissue 1 December 1988https://pubs.acs.org/doi/10.1021/ja00233a036https://doi.org/10.1021/ja00233a036research-articleACS PublicationsRequest reuse permissionsArticle Views584Altmetric-Citations182LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Chemotherapy And Radiotherapy In Locally Advanced Cervical Cancer (1995)

Radiotherapy has been standard therapy for locally advanced squamous cell cervical cancer. Neoadjuvant chemotherapy is being studied to improve responses and survival. We report a phase II study in locally advanced squamous cell cervical cancer (FIGO stages III and IVA) using chemotherapy with bleomycin, methotrexate and cisplatin (BMP) followed by radical radiotherapy. Of the 35 patients, 31 in stage III and 4 in stage IVA, 3 complete responses (CR) and 22 partial responses (PR) were achieved after chemotherapy treatment. Thirty-one patients completed radiotherapy; 19 achieved CR and 4 PR. Five-year actuarial survival for the entire group was 45% (95% confidence interval, 37-53%) with a median survival of 56 months. Patients with CR had a significantly better survival: the 5-year actuarial survival was 74% (95% CI, 59-89%). Recurrence developed in 4 of 19 patients. The most frequent side-effects were nausea and vomiting. Myelosuppression and impaired renal function also occurred. There was no evidence of radiotherapy toxicity enhancement. The stage and Karnofsky index were significant prognostic factors. It is concluded that BMP chemotherapy in advanced cervical cancer is effective and, followed by radiotherapy, allows a good control of this tumor. The group of patients with complete response have a low rate of recurrences and a long survival chance.
Relative contributions of the AcrAB, MdfA and NorE efflux pumps to quinolone resistance in Escherichia coli (2003)

Quinolones are widely used, broad-spectrum antimicrobial agents. In screens for genes that, when overexpressed, allow Escherichia coli to grow on otherwise lethal concentrations of the fluoroquinolone norfloxacin, the ydhE gene was identified. We have shown that ydhE encodes a multidrug efflux pump with a narrower substrate range than that of its closest homologue, encoded by norM, and named the gene norE. The relative contributions to drug resistance of NorE compared with the two other known E. coli quinolone pumps, AcrAB and MdfA, have been defined. Overexpression of each of the three pumps separately resulted in roughly similar levels of quinolone resistance, whereas simultaneous overexpression of norE or mdfA in combination with acrAB gave synergic increases in quinolone resistance. The level of quinolone resistance mediated by efflux pumps seems to be constrained to an approximately 10-fold maximum, even with increased production of the pumps. We measured the drug resistance of an isogenic set of strains containing the various permutations of single, double and triple drug efflux pump mutants. The DeltanorE and DeltamdfA mutants were somewhat more susceptible to fluoroquinolones than the parent strain, and acrAB mutants were four- to six-fold more susceptible. Mutants lacking two or all three efflux pumps were not significantly more susceptible to fluoroquinolones than those lacking only one of the three pumps.
Four Core Genotypes mouse model: localization of the Sry transgene and bioassay for testicular hormone levels (2015)

The Sry transgene in FCG mice is present in multiple copies at one locus on chromosome 3, which does not interrupt known genes. XX and XY mice with the same type of gonad do not show evidence of different androgen levels prenatally.
Time Resolved CW-EPR Spectroscopy of Powdered Samples:  Electron Spin Polarization of a Nitroxyl Radical Adsorbed on NaY Zeolite, Generated by the Quenching of Excited Triplet Ketones (2001)

Chemically induced dynamic electron polarization (CIDEP) generated in a faujasite zeolite (NaY) by the interaction between a stable free radical (4-oxo-TEMPO) and the triplet state of benzophenone was investigated by time-resolved electron spin resonance spectroscopy (TR-CW-EPR). The TR-CW-EPRs were performed by either pulling a long tube containing powdered zeolite through the EPR cavity during the laser irradiation, or by flowing a liquid transport medium (polydimethylsiloxane) for the zeolite powder, through a flat cell in the EPR cavity. CIDEP was observed for intermolecular triplet quenching (benzophenone triplets with 4-oxo-TEMPO) and intramolecular triplet quenching using a covalently linked TEMPO-benzophenone molecule. The identification of the polarized nitroxide structure was confirmed by employing both 14N and 15N 4-oxo-TEMPO isotopomers. The kinetics of the triplet quenching inside the zeolite were studied by diffuse reflection laser flash photolysis.
CORRECTION (1981)

Abstract A careless editorial oversight led to the omission of a line added in proof by the author. So, with my apologies, please note that on p. 107 of the article on Amadis de Gaule by Stephen Rawles (June 1981), there should appear between States 1 and 3 of Edition IV, I : State 2: Jean Longis: Ghent (not seen).
Simultaneously monitoring of tissue O<inf>2</inf> and CO<inf>2</inf> partial pressures by means of miniaturized implanted fiber optical sensors (2009)

A novel opto-chemical sensor instrumentation based on fiber optical micro-sensors for the simultaneous detection of pO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and pCO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> in tissues is presented. The adopted sensing principle for both parameters is the measurement of luminescence lifetime via phase modulation fluorometry. Respect to currently used blood-gas analysers that require blood sampling and are associated with blood loss, this instrumentation allows on-line continuous measurements. Compared to electrochemical micro sensors, it is advantageous because of intrinsic higher sensitivity, no analyte consumption and less electromagnetic interferences. The results of the laboratory characterization and of tests in in vivo experiments of the proposed instrumentation are reported.
Development of silicon module with TSVs and global wiring (L/S=0.8/0.8&#x00B5;m) (2009)

In recent years, in order to achieve high density and high transmission speed between chips, various kinds of silicon modules have been developed.
An approach for integrating complementary– alternative medicine into primary care (2003)

Given patients' demands and utilization of CAM therapies, despite the lack of evidence, there is an increasing need to address how CAM therapies can be integrated into conventional medical systems. These suggestions should respond to patient's expectations and needs, but at the same time maintain accepted standards of medical and scientific principles of practice.
Enhanced digital coherent receiver for high spectral-efficiency dual-polarization quadrature duobinary systems (2010)

To enable linear impairment compensation and increase OSNR tolerance, a digital coherent receiver incorporating symbol-rate blind equalization and maximum-likelihood sequence detection is proposed and experimentally verified at 43Gbit/s for dual-polarization quadrature duobinary systems.
Massive blood transfusion for trauma patients (2012)

Transfusion of large amounts of blood products is a complex and changing practice. British and American military experience of the process in Afghanistan and Iraq, and the findings of the international CRASH 2 study (Shakur et al 2010), have led to changes in practice (Moor et al 2009). The procedure has evolved into a targeted therapy involving a selection of blood products and drugs. This article explores the practice of massive transfusion adopted by the British military in Afghanistan, including the drugs used, and describes the training given to staff in a controlled environment.
Compressed domain JPEG2000 image indexing method employing full packet header information (2008)

In this paper we propose a new indexing method for comparing image contents in the JPEG2000 compressed domain. Comparing image contents of the JPEG2000 coded images in the pixel domain requires image decompression, which imposes intensive computational processes of the inverse discrete wavelet transform and the arithmetic decoding. On the other hand, the first decoding stage of the JPEG2000 standard is packet header decoding, which is a simple process, but provides valuable information about the code blocks in the packet. In this paper we use packet header information for JPEG2000 image indexing. The proposed method exploits full packet header information including the number of non-zero bit-planes, the number of coding passes and the code block length for indexing the JPEG2000 compressed images. Experimental results show that the proposed method provides a better performance compared to other JPEG2000 compressed domain indexing techniques and even outperforms the pixel-based image indexing techniques such as the Gabor filter.
Resonant In-Well Pumping of GaSb-Based VECSELs Emitting in the 2.X μm Wavelength Regime (2007)

We report on the epi-layer design and lasing characteristics of GaSb-based VECSELs emitting at 2.35mum optimized for resonant optical in-well pumping around 1.95mum. Compared to conventional barrier-pumped devices, the power conversion efficiency is significantly increased.
Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens (2012)

The Sterilray™ Disinfection Wand is a novel environmental disinfection technology that rapidly kills C. difficile spores and other healthcare-associated pathogens on surfaces. However, the presence of organic matter reduces the efficacy of far-UV radiation, possibly explaining the more modest results observed on surfaces in hospital rooms that were not pre-cleaned.
Vehicle thermal control with a variable area inlet (2002)

This study developed a variable area inlet and controller that regulated the temperature of an electrical component with ram air. The intent of the variable area inlet was to reduce vehicle drag by eliminating inefficiencies associated with component cooling and fixed area inlets. These inefficiencies arise from vehicles moving at varying speeds through varying air temperatures. The system was successful in regulating the component temperature. A nonlinear simulation model was built in MATLAB/sup TM/ SIMULINK/sup TM/ and the thermal plant in the simulation was based on the electrical component's convective heat transfer coefficient, empirically derived in terms of the Nusselt number. Proportional, proportional-derivative (PD), and proportional-integral-derivative (PID) controllers were designed, built, and tested.
76. The removal of toluene-p-sulphonyl groups from sulphonamides. Part I. Synthesis of Schiff bases (1965)

W. Paterson and G. R. Proctor, J. Chem. Soc., 1965, 485 DOI: 10.1039/JR9650000485
Anti- <i>Aspergillus fumigatus</i> Efficacy of Pentraxin 3 Alone and in Combination with Antifungals (2004)

The collectin pentraxin 3 (PTX3) is an essential component of host resistance to pulmonary aspergillosis. Here we examined the protective effects of administration of PTX3 alone or together with deoxycholate amphotericin B (Fungizone) or liposomal amphotericin B (AmBisome) against invasive aspergillosis in a murine model of allogeneic bone marrow transplantation. PTX3, alone or in combination with the polyenes, was given intranasally or parenterally either before, in concomitance with, or after the intranasal infection with Aspergillus fumigatus conidia. Mice were monitored for resistance to infection and parameters of innate and adaptive T-helper immunity. The results showed the following: (i) complete resistance to infection and reinfection was observed in mice treated with PTX3 alone; (ii) the protective effect of PTX3 was similar or superior to that observed with liposomal amphotericin B or deoxycholate amphotericin B, respectively; (iii) protection was associated with accelerated recovery of lung phagocytic cells and T-helper-1 lymphocytes and concomitant decrease of inflammatory pathology; and (iv) PTX3 potentiated the therapeutic efficacy of suboptimal doses of either antimycotic drug. Together, these data suggest the potential therapeutic use of PTX3 either alone or as an adjunctive therapy in A. fumigatus infections.
[Study of mechanisms of anti-irradiation effects of interleukin-1beta in long-term bone marrow cultures]. (2002)

The influence of betaleukin (human recombinant interleukin-1 beta) on the processes of postirradiation recovery of haemopoietic precursors (GM-CFC) and the level of granulocyte-macrophag colony-stimulating factor (GM-CSF) were studied in long-term bone marrow cultures after gamma-irradiation with a dose 2 Gy. Then the betaleukin action on the contents of GM-CFC and induction of GM-CSF in the non irradiated cultures was studied. It was shown that betaleukin increased the induction of GM-CSF and raised the contents of GM-CFC in long-term bone marrow cultures, and the maximal increase of a GM-CSF level and GM-CFC amount was marked in 20 hours after introduction. At an irradiation of long-term bone marrow cultures in conditions of betaleukin introduction 20 hours prior to influence of radiation the smaller degree of damage and faster recovery of GM-CFC was observed. The data in this report suggest that one of the mechanisms of antiirradiation action of betaleukin apparently is connected to the action of the preparation on hematopoietic microenvironment cellular elements, that causes the release of a colony-stimulating factor and stimulation of recovery of haemopoietic precursors.
CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells (2006)

Activation of natural killer (NK) cell cytotoxicity requires adhesion and formation of a conjugate with a susceptible target cell, followed by actin polymerization, and polarization of the microtubule organizing center (MTOC) and cytolytic granules to the NK cell immune synapse. Here, by using the YTS NK cell line as a model, CD28 is shown to be an activating receptor. It signals cytotoxicity in a process dependent on phosphoinositide-3 kinase activation, leading to sustained extracellular signal-regulated kinase 2 (ERK2) phosphorylation. ERK and phospho-ERK localize to microtubule filaments. Neither conjugation with targets nor actin polymerization is affected by blocking ERK2 activation. However, both polarization of the MTOC and cytolytic granules to the synaptic region and NK cell cytotoxicity are strongly reduced by blocking ERK2 activation. A role for the CD28/CD80 interaction in cytotoxicity of human peripheral NK cells also was established. By contrast, lymphocyte function-associated antigen 1 (LFA-1) ligation transduces only a transient ERK2 activation and fails to induce killing in YTS cells. Thus, in YTS cells, a CD28 signal is used to polarize the MTOC and cytolytic granules to the NK cell immune synapse by stimulating sustained ERK2 activation.
<title>Compound Holographic Interference And Conventional Microscope And Its Application On Crystal Growth From Solution</title> (1981)

A compound microscope is described which consists of a combination of a holographic interference microscope and a conventional microscope. Both systems can be optimized independently for fringe and image contrast, respectively. Both these systems proved to be indispensable for the description of complex phenomena, such as etch pit formation. On their own, they presented incomplete and even highly misleading information. The complete system combines i) the highly corrected image and long free working range of microscopy, with ii) the large vertical resolution and overall spatial information of interferometry and with iii) the increased depth of imaged volume and potentialities for time sequential observations of holography. The coherence of the light enables interference microscopy during crystal growth from a bulk solution. With the compound microscope the development of high index (or vicinal) faces, step bunches and etch pits were recorded during crystal growth and/or dissolution. Simultaneously also both concentration gradients and equiconcentration profiles surrounding the growing (or dissolving) crystal were made visible. Microinterferograms were obtained from i) interference of the reconstructed image (crystal, solution or free space) of a single exposure hologram with a real object beam; from ii) the superposed reconstructions of two such holograms; and from iii) the reconstruction of double exposure holograms (time sequential). The applicability of the various techniques is discussed with respect to the study of crystal growth processes.
Novel DNA-Binding Proteins Regulate Intestine-Specific Transcription of the Sucrase-Isomaltase Gene (1992)

Sucrase-isomaltase (SI) is an enterocyte-specific gene which exhibits a complex pattern of expression during intestinal development and in the adult intestinal mucosa. In the studies described in this report, we demonstrate that enterocyte-specific transcription of the SI gene is regulated by an evolutionarily conserved promoter that extends approximately 180 bp upstream of the transcription start site. DNase I footprint analysis allowed the identification of three nuclear protein-binding sites within the SI promoter (SIF1, SIF2, and SIF3 [SI footprint]), each of which acted as a positive regulatory element for transcription in intestinal cell lines. SIF1 was shown to bind nuclear protein complexes present in primary mouse small intestinal cell and in an intestinal cell line (Caco-2). However, SIF1-binding proteins were absent in a variety of other epithelial and nonepithelial cells. In vitro mutagenesis experiments demonstrated that the SIF1 site is required for high-level promoter activity in intestinal cells. The SIF3 element formed prominent binding complexes with intestinal and liver nuclear extracts, whereas nuclear proteins from other epithelial and nonepithelial cells formed weaker complexes of different mobilities. The SIF2 element bound nuclear proteins in a pattern similar to that of SIF3, and cross-competition studies suggested that SIF2 and SIF3 may bind the same nuclear proteins. Taken together, these data have allowed the identification of novel DNA-binding proteins that play an important role in regulating intestine-specific transcription of the SI gene.
Piezoelectric Properties of Pb(Mg <sub>1/3</sub> Nb <sub>2/3</sub> )O <sub>3</sub> PbTiO <sub>3</sub> ‐PbZrO <sub>3</sub> Ceramics Modified with Certain Additives (1966)

Effects of additives on the piezoelectric properties of Pb(Mg 1/3 Nb 2/3 )O 3 ‐PbTiO 3 ‐PbZrO 3 ceramics in a perovskite‐type structure are described. The tetragonality of Pb(Mg 1/3 Nb 2/3 ) 0.375 ‐Ti 0.375 Zr 0.25 O 3 ceramics increased with the addition of NiO, Cr 2 O 3 , or Fe 2 O 3 but decreased with the addition of MnO 2 or CoO. The dielectric and piezoelectric properties of the base composition were improved markedly through selection of additives in proper amounts. Addition of NiO yielded a high dielectric constant and planar coupling coefficient for compositions at the morphotropic transition boundary. High mechanical Q ‐factors and low electrical dissipation factors were obtained by addition of MnO 2 . Addition of both NiO and MnO 2 produced a mechanical Q ‐factor of 2051 and a planar coupling coefficient of 0.553. The resonant frequency of Pb(Mg 1/2 Nb 2/3 ) 0.4375 Ti 0.4375 zr 0.125 O 3 containing MnO 2 had very low temperature and time dependence. The microstructure indicated that ceramics with a high mechanical Q ‐factor had a fine, uniform grain structure. Addition of Cr 2 O 3 retarded grain growth and addition of MnO 2 , NiO, CoO, or Fe 2 O 3 promoted grain growth in the ternary system.
149 Extent of Female Partner Sexual Function Improvement in Female Partners of Men With Peyronie's Disease Who Received Collagenase Clostridium Histolyticum (2018)

To examine the impact of erectile dysfunction severity in men with Peyronie's disease (PD) on improvement of female partner satisfaction after collagenase clostridium histolyticum (CCH) treatment. Men with PD (penile curvature ≥30° and ≤90°) who previously received placebo during the IMPRESS I or II trials and their female partners, who were willing to participate, were included in a separate subsequent open-label, phase 3 study. Men received up to 4 treatment cycles; cycles were separated by 6 weeks. Each treatment cycle consisted of 2 injections of CCH 0.58 mg separated by 24 to 72 hours. The second injection was followed by 6 weeks of daily penile plaque modeling. Men completed the International Index of Erectile Function (IIEF) at baseline and week 36. The IIEF is a 15-item questionnaire that assesses 5 domains (erectile function, orgasmic function, sexual desire, intercourse satisfaction, and overall satisfaction) of male sexual function. Female sexual function was assessed at baseline and week 36 using the Female Sexual Function Index (FSFI), a 19-item questionnaire that measures desire or arousal, lubrication, orgasm, satisfaction, and pain. The relationship between baseline IIEF male erectile dysfunction and improvement of female sexual function after CCH therapy in males was examined using regression analysis (Pearson correlation coefficient [r]).