gebhart/patrepeval huggingface dataset:
Managed Care and the Evolving Role of the Clinical Social Worker in Mental Health (2003)

This article discusses developments for practitioners in mental health care with the advent of managed care. With managed care's influence and new cost-containment strategies, the roles of clinical social workers, clinical psychologists, and psychiatrists are evolving, creating role conflict and competition. Along with changes in the utilization and definition of mental health practitioners' responsibilities, managed care has influenced issues such as private practice, mode of treatment, the use of outcome measurement and management, and the importance of case management. This article outlines the changes that have occurred and provides projections for the future.
The Trematode Parasites of North Queensland. III. (1915)

During the past year a considerable number of fishes has been forwarded to the Institute for examination. The great majority have been marine fishes obtained from Cleveland Bay, or from the reefs off Magnetic Island, but a few fresh-water fishes from local creeks have also been included.
Differential Effects of IL-12 on Tregs and Non-Treg T Cells: Roles of IFN-γ, IL-2 and IL-2R (2012)

Complex interactions between effector T cells and Foxp3(+) regulatory T cells (Treg) contribute to clinical outcomes in cancer, and autoimmune and infectious diseases. Previous work showed that IL-12 reversed Treg-mediated suppression of CD4(+)Foxp3(-) T cell (Tconv) proliferation. We and others have also shown that Tregs express T-bet and IFN-γ at sites of Th1 inflammation and that IL-12 induces IFN-γ production by Tregs in vitro. To investigate whether loss of immunosuppression occurs when IFN-γ is expressed by Tregs we treated mouse lymphocyte cultures with IL-12. IFN-γ expression did not decrease the ability of Tregs to suppress Tconv proliferation. Rather, IL-12 treatment decreased Treg frequency and Foxp3 levels in Tregs. We further showed that IL-12 increased IL-2R expression on Tconv and CD8 T cells, diminished its expression on Tregs and decreased IL-2 production by Tconv and CD8 T cells. Together, these IL-12 mediated changes favored the outgrowth of non-Tregs. Additionally, we showed that treatment with a second cytokine, IL-27, decreased IL-2 expression without augmenting Tconv and CD8 T cell proliferation. Notably, IL-27 only slightly modified levels of IL-2R on non-Treg T cells. Together, these results show that IL-12 has multiple effects that modify the balance between Tregs and non-Tregs and support an important role for relative levels of IL-2R but not for IFN-γ expression in IL-12-mediated reversal of Treg immunosuppression.
Practical Guidance for Flux Chamber Measurements of Fugitive Volatile Organic Emission Rates (1992)

Abstract Hazardous waste sites and industrial facilities contain area sources of fugitive emissions. Emission rate measurements or estimates are necessary for air pathway assessments for these sources. Emission rate data can be useful for the design of emission control and remediation strategies as well as for predictive modeling for population exposure assessments. This paper describes the use of a direct emission measurement approach – the enclosure approach using an emission isolation flux chamber – to measure emission rates of various volatile organic compounds (VOCs) from contaminated soil and water. A variety of flux chamber equipment designs and operating procedures have been employed by various researchers. This paper contains a review of the design and operational variables that affect the accuracy and precision of the method. Guidance is given as to the optimum flux chamber design and operating conditions for various types of emission sources. Also presented is a generic quality control program that gives the minimum number of duplicate, blank, background, and repeat samples that should be performed.
Deletion Analysis of Protein Kinase C  Reveals a Novel Regulatory Segment (1998)

Using a combined pharmacological and genetic approach, we have identified aa 260-280 in the C2 region as a critical factor in the catalytic function of protein kinase Calpha (PKCalpha). Progressive truncations from the N-terminus as well as selected internal deletion mutants were expressed in Saccharomyces cerevisiae and tested for altered sensitivity to dequalinium, a PKC inhibitor whose target site was previously mapped to the catalytic domain. PKC mutants representing truncations of up to 158 amino acid residues (aa) from the N-terminus (ND84 and ND158) displayed 60-63% inhibition of kinase activity by 50 microM dequalinium, somewhat more sensitive than the wild-type PKCalpha enzyme (45% inhibition). Mutant ND262, lacking N-terminal aa 1-262, was inhibited by almost 72% with 50 microM dequalinium, but mutant ND278, which lacked an additional 16 aa, was inhibited by only 9% of total activity. This result suggests that a C-terminal segment of the C2 region (aa 263-278) influences inhibition by dequalinium at low micromolar concentrations. An internal deletion mutant (D260-280) which retains the entire primary structure of PKCalpha except for aa 260-280, was similarly inhibited by only 4% with 50 microM dequalinium. In the absence of dequalinium and despite the presence of a nearly complete regulatory domain, this mutant exhibited constitutive activity (both in vitro and in a phenotypic assay with S. cerevisiae) that could not be further stimulated even by the potent activator TPA. Taken together, our findings suggest that, in the native structure of PKCalpha, the segment described by aa 260-280 regulates PKCalpha activity and influences the sensitivity of PKCalpha to dequalinium.
Two-Dimensional Stress-Magnetization Properties of Grain-Oriented Silicon Steel Sheets. (1994)

The effects of tensile and compressive stress on the magnetization changes, under a constant magnetic field, of grain-oriented silicon steel sheets inclined from the rolling direction were investigated. Magnetization changes due to tension in a low magnetic field appeared only in the longitudinal direction of the sample, and the magnetization decreased. Beyond that magnetic field, the sample showed a two-dimensional hysteresis loop due to the application of tension. The appearance of the twodimensional hysteresis loop was due to the magnetization vector being forced to rotate in the rolling direction by the application of tension. The maximum transverse magnetization change appeared in the 10° sample. On the other hand, magnetization changes due to the compression under the same magnetic field did not show a two-dimensional hysteresis loop.
<title>Resolution issues in reflective microdisplays</title> (1999)

Projection system based on microdisplays have the advantage of lower cost and weight due to the reduction in size of the image generating devices and associated optics. Reflective devices are favored because the pixel aperture remains high for small pixels. However, at high resolution the performance is compromised by the reduction in size of the pixel. Increased diffraction loss with reduction in pixel size reduces the optical throughput of the projector. Electric field fringing is enhanced for smaller pixels in liquid crystal devices, sacrificing throughput in general. Computed diffraction losses are presented for a range of pixel geometry and projection f/numbers. An approximation for fringe field modulation is used to estimate throughput losses associated with field fringing.
Impact of epitaxial growth at the heterointerface of a-Si:H∕c-Si solar cells (2007)

The authors have demonstrated that interface structures of heterojunction solar cells consisting of hydrogenated amorphous silicon (a-Si:H) and crystalline silicon (c-Si) have quite large impact on the solar cell performance. In particular, unintentional epitaxial growth was found to occur during an intended a-Si:H i-layer growth on c-Si in plasma-enhanced chemical vapor deposition (PECVD). By the formation of the epitaxial layer at the interface, the solar cell efficiency decreases significantly. Their result shows that the epitaxial layer is formed rather easily in PECVD, even without the presence of H2 gas, and may have affected many previous studies on a-Si:H∕c-Si solar cells seriously.
Vapor‐Phase Etching and Polishing of Gallium Arsenide Using Hydrogen Chloride Gas (1975)

Vapor‐phase etching of (100) and () substrates has been conducted in gas mixtures. Specular surfaces, suitable for epitaxy, were obtained for substrates doped with Cr, Te, Si, and Zn when the substrates were etched at temperatures above 870°C. It is shown that the etching reaction is mass‐transport limited at these temperatures for both (100) and () surfaces. At lower temperatures, faceting results from the unequal etch rates for the different orientations. Etch rates of 0.02–14 μm/min were obtained in this study.
An Investigation of Antibiotic and Drug Residues in Fish (1976)

The use of antibiotics and drugs in fish farming has prompted an investigation into the elimination of these residues from fish muscle. Young rainbow trout were given intraperitoneal injections of either chloramphenicol, framycetin, oxytetracycline or sulphadiazine/ trimethoprim and muscle tissue was examined by microbiological assay over a period of weeks for the presence of active residues. The effect of the method of administration of two of the drugs was also investigated and the results discussed.
Research and Implementation of a Power Controlling Strategy Based on CPU Utilization (2009)

With the rapid increasing in server power consumption,the cost of electricity has become a main part of the total cost of ownership.At the same time,a large number of X86 servers currently are in use,and the average utilization rate of them has been maintained at 10%～15%,wasting a lot of power.In order to improve efficiency in the use of server power,this paper presents a server power control strategy based on the CPU utilization,that in real-time adjusts the server power without affecting user experience.The strategy has been applied in the Dawning self-adaptive energy-saving systems(PowerConf.),to some extent,alleviate the increasingly serious problem of server power consumption.
Hipnose em pacientes oncológicos: um estudo psicossomático em pacientes com câncer de próstata (2012)

A presente pesquisa tem como objetivo interpretar e compreender o impacto das ressignificações vivenciais experienciadas em estado hipnótico por pacientes com câncer de próstata sobre a autopercepção de saúde, crença no tratamento e capacidade de prospectar o futuro. Foram acompanhados 12 sujeitos durante 5 sessões de 1 hora de hipnoterapia escalonadas semanalmente. Os instrumentos consistiram em entrevistas individuais, intervenções hipnóticas e registros das entrevistas. Foi eleita a Técnica de Análise Temática para a seleção de temas a serem analisados. Os discursos emergidos nas entrevistas iniciais apresentaram semelhanças no que concerne às vivencias coexistenciais e os tópicos notáveis analisados foram: Sentimentos e impulsos ao impacto do diagnóstico, Significado do câncer e crença na cura, Autopercepção da melhora do câncer, Retomada da capacidade de prospectar o futuro. A conclusão indicou que 100% dos pacientes acompanhados referiram melhora na saúde, certeza da cura, retomada do humor e incremento nas estratégias de enfrentamento às situações estressógenas.
Systems-level design of ion transport membrane oxy-combustion power plants (2011)

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2011.
A Divide and Conquer Framework for Distributed Graph Clustering (2015)

Graph clustering is about identifying clusters of closely connected nodes, and is a fundamental technique of data analysis with many applica-tions including community detection, VLSI net-work partitioning, collaborative filtering, etc. In order to improve the scalability of existing graph clustering algorithms, we propose a novel divide and conquer framework for graph clustering, and establish theoretical guarantees of exact recovery of the clusters. One additional advantage of the proposed framework is that it can identify small clusters – the size of the smallest cluster can be of size o( p n), in contrast to Ω(
Problems Associated with the EEA Stapling Technique for Esophagojejunostomy after Total Gastrectomy (1989)

Since November 1980, the EEA stapling device has been used to create an end-to-side esophagojejunostomy in 238 patients who underwent total gastrectomy. Failures in the stapling technique were divided into two groups: immediate and delayed. Immediate failures were observed and corrected at the time of surgery. In ten cases, the muscular layer of the esophagus was disrupted, and in three the mucosal layer of the jejunum was disrupted. There were 18 delayed complications: eight cases of anastomotic leakage (3.4%), and ten of stenosis (4.2%). The leakage in one case was classified as major, and those in the other seven as minor. Of the ten stenosis cases, there were five of membranous stricture, four of granular stricture, and one of narrowing after major leakage healing. Only this last case required further surgical treatment. The other nine were successfully dilated either endoscopically or by bougienage.
<title>Imaging artifacts due to pixel spatial sampling smear and amplitude quantization in two-dimensional visible imaging arrays</title> (1999)

In this paper, we studied the imaging effects of pixel spatial-sampling and scan-velocity mismatch in 2D visible image sensors. these effects were examined experimentally by projecting bar pattern sequences of varying spatial frequency on two different devices and by comparing their outputs with the results of a corresponding imaging simulation. Beat patterns and aliased spatial frequencies were observed by imaging the bar pattern sequences onto an area CMOS `active pixel' sensor. Image phase reversal effects were observed by inducing a systematic mismatch between the scan velocity of a bar pattern `sunburst' areal image and the corresponding velocity of the clocked image charge in a time-delay-and-integration CCD image sensor. The visual image effects of an analog-to-digital converter's (ADC) pixel amplitude quantization, specifically integral nonlinearity (INL) and differential nonlinearity (DNL) were studied using two very different input images. The INL and DNL patterns, obtained from measurements on a 14-bit, video ADC were scaled and then imbedded in the response characteristics of these two images. Various scaling of these INL and DNL patterns were used. the results obtained show artifacts varying in impact from insignificant to clearly degrading.
Comparative tests of Pitot-static tubes (1935)

Comparative tests were made on seven conventional Pitot-static tubes to determine their static, dynamic, and resultant errors. The effect of varying the dynamic opening, static opening, wall thickness, and inner-tube diameter was investigated. Pressure-distribution measurements showing stem and tip effects were also made. A tentative design for a standard Pitot-static tube for use in measuring air velocity is submitted.
Animating human athletics (1995)

This paper describes algorithms for the animation of men and women performing three dynamic athletic behaviors: running, bicycling, and vaulting. We animate these behaviors using control algorithms that cause a physically realistic model to perform the desired maneuver. For example, control algorithms allow the simulated humans to maintain balance while moving their arms, to run or bicycle at a variety of speeds, and to perform a handspring vault. Algorithms for group behaviors allow a number of simulated bicyclists to ride as a group while avoiding simple patterns of obstacles. We add secondary motion to the animations with springmass simulations of clothing driven by the rigid-body motion of the simulated human. For each simulation, we compare the computed motion to that of humans performing similar maneuvers both qualitatively through the comparison of real and simulated video images and quantitatively through the comparison of simulated and biomechanical data.
N-Substituted organo(silyliminomethyl)stannanes: synthetic equivalent to organosilylcarbonyl anion and carbonyl dianion (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN-Substituted organo(silyliminomethyl)stannanes: synthetic equivalent to organosilylcarbonyl anion and carbonyl dianionYoshihiko Ito, Takaharu Matsuura, and Masahiro MurakamiCite this: J. Am. Chem. Soc. 1987, 109, 25, 7888–7890Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/ja00259a051https://doi.org/10.1021/ja00259a051research-articleACS PublicationsRequest reuse permissionsArticle Views338Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development (2007)

Specification of cell lineages in mammals begins shortly after fertilization with formation of a blastocyst consisting of trophectoderm, which contributes exclusively to the placenta, and inner cell mass (ICM), from which the embryo develops. Here we report that ablation of the mouse Tead4 gene results in a preimplantation lethal phenotype, and TEAD4 is one of two highly homologous TEAD transcription factors that are expressed during zygotic gene activation in mouse 2-cell embryos. Tead4(-/-) embryos do not express trophectoderm-specific genes, such as Cdx2, but do express ICM-specific genes, such as Oct4 (also known as Pou5f1). Consequently, Tead4(-/-) morulae do not produce trophoblast stem cells, trophectoderm or blastocoel cavities, and therefore do not implant into the uterine endometrium. However, Tead4(-/-) embryos can produce embryonic stem cells, a derivative of ICM, and if the Tead4 allele is not disrupted until after implantation, then Tead4(-/-) embryos complete development. Thus, Tead4 is the earliest gene shown to be uniquely required for specification of the trophectoderm lineage.
Airborne Aerosol Generation During Endonasal Procedures in the Era of COVID‐19: Risks and Recommendations (2020)

Transnasal drill and cautery use is associated with significant airborne particulate matter production in the range of 1 to 10 μm under surgical conditions. During simulated clinical activity, airborne aerosol generation was seen during nasal endoscopy, speech, and sneezing. Intact or VENT-modified N95 respirators mitigated airborne aerosol transmission, while standard surgical masks did not.
Competence of dogs as reservoirs for Lyme disease spirochetes (Borrelia burgdorferi) (1994)

Dogs become infected with Borrelia burgdorferi after being bitten by infected adult ticks. However, it is not known whether dogs are competent reservoirs of the organism, that is, it is not known whether infected dogs can subsequently transmit the bacterium to feeding immature ticks. To determine reservoir competence of dogs, 11 Beagles were experimentally infected by means of challenge exposure to infected adult deer ticks (Ixodes scapularis). Three weeks later, larval ticks were allowed to feed on the dogs. Engorged larvae were collected, allowed to molt to the nymph stage, and tested, by means of a direct fluorescent antibody assay, to detect the presence of B burgdorferi organisms. Overall, 78% of immature ticks tested were found to have become infected. We concluded that dogs might serve to increase human risk of exposure to B burgdorferi-infected ticks and, therefore, should be protected from exposure to infected ticks as well as immature ticks seeking a blood meal.
Virtual environments for aerospace training (2002)

Virtual Environments (VEs) have the potential to significantly enhance the training of NASA astronauts and ground-based personnel for a variety of activities. At the same time this technology offers significant cost savings and increased training throughput. Issues being explored include the use of VEs to replicate features of microgravity environments that are not available in ground-based simulators, the degree of fidelity needed for effective training, the addition of haptic (tactile, force, temperature) feedback to VEs, and the feasibility of using VEs on orbit for "just-in-time training" and mission planning. The results of the use of virtual environments for training the Hubble Space Telescope Repair and Maintenance Mission flight team is discussed. In addition, progress on the development of shared virtual environments for training is presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Immunological identification and characterization of a delayed rectifier K+ channel polypeptide in rat brain. (1991)

Antibodies specific for the drk1 polypeptide were used to characterize the corresponding protein in rat brain. Recombinant and synthetic immunogens containing fragments of the drk1 polypeptide were produced. Antibodies raised to these immunogens display monospecific reactions with the same 130-kDa polypeptide on immunoblots of adult rat brain membranes. Immunoprecipitation of 125I-labeled brain membranes identifies a 38-kDa peptide in tight association with the drk1 polypeptide. Immunohistochemical staining of sections of adult rat cortex shows that drk1 protein is restricted to neurons, where staining is present on dendrites and cell bodies but not on axons. These studies point to the value of such immunological reagents to the further characterization of the components of this delayed rectifier K+ channel in the mammalian central nervous system.