gebhart/patrepeval huggingface dataset:
Optimization of isolation and further characterization of umbilical cord blood‐derived very small embryonic/ epiblast‐like stem cells (VSELs) (2009)

Because of their small size and density, umbilical cord blood (UCB)-derived very small embryonic/epiblast-like stem cells (VSELs) are usually lost at various steps of UCB preparation. Accordingly, we noticed that a significant number of these cells, which are smaller than erythrocytes, are lost during gradient centrifugation over Ficoll-Paque as well as during routine volume depletion of UCB units before freezing. To preserve these cells in final UCB preparations, we propose a relatively short and economical three-step isolation protocol that allows recovery of approximately 60% of the initial number of Lin(-)/CD45(-)/CD133(+) UCB-VSELs present in freshly harvested UCB units. In this novel approach (i) UCB is lysed in a hypotonic ammonium chloride solution to deplete erythrocytes; (ii) CD133(+) including VSELs cells are enriched by employing immunomagnetic beads; and subsequently (iii) Lin(-)/CD45(-)/CD133(+) cells are sorted by fluorescence-activated cell sorting. The whole isolation procedure takes approximately 2-3 h per UCB unit and isolated cells are highly enriched for an Oct-4(+) and SSEA-4(+) population of small Lin(-)/CD45(-)/CD133(+) cells.
Diagnostically and Experimentally Useful Panel of Strains from the <i>Burkholderia cepacia</i> Complex (2000)

Two new species, Burkholderia multivorans and Burkholderia vietnamiensis, and three genomovars (genomovars I, III, and IV) currently constitute the Burkholderia cepacia complex. A panel of 30 well-characterized strains representative of each genomovar and new species was assembled to assist with identification, epidemiological analysis, and virulence studies on this important group of opportunistic pathogens.
Don't bet on it... The representation of gambling in baseball cinema (1996)

This paper examines the role of baseball films in the game's ideological war on gambling. While the central purpose behind baseball's strict prohibitions against gambling by players has been to protect the economic interests of team owners, the issue of gambling has been consistently presented in the game's cultural ideology as a moral issue, rather than an economic one. This process serves as a means of disciplining the baseball worker, and as a means of enhancing the game's appeal to middle‐class audiences. Baseball films have been an important site of the construction of this ideology, consistently portraying gambling as a moral transgression against the national pastime.
A Novel Human Gait Recognition Method by Segmenting and Extracting the Region Variance Feature (2006)

Existing methods of gait recognition suffer from some shortcomings, which are discussed at the beginning of the full paper. In order to suppress these shortcomings as much as possible, we proposed a new automatic gait recognition approach based on the region variance feature. Firstly, the binary silhouette of a walking person is detected from each frame of the monocular image sequences. Then we divide the two dimensional silhouette of the walker into three regions (head region, trunk region and legs region). Next, the variance features of these regions are extracted respectively. Together with the ratio of the silhouette’s height and width, the gait signature vectors are constructed to identify different subjects. Finally, similarity measurement based on the gait cycles and NN and KNN classifiers are carried out to recognize the different subjects. Experimental results show that the proposed novel method is very effective and correct recognition rates are over 92% and 97% on UCSD and CMU database, respectively.
Intracranial Metastases (2008)

Metastasis to the cranium or its intracranial contents is a common neurologic complication of cancer. Although skull metastases are more common than parenchymal brain metastases, the latter are much more likely to be symptomatic (Fig. 5–1). Symptoms of brain metastases may be the presenting complaint in patients not known to have cancer.
The Effect of Magnetic Field on HTS Leads What Happens when thePower Fails at RAL? (2007)

The key to being able to operate the MICE superconducting solenoids on small coolers is the use of high temperature superconducting (HTS) leads between the first stage of the cooler and the magnet, which operates at around 4.2 K. Because MICE magnets are not shielded, all of the MICE magnets have a stray magnetic field in the region where the coolers and the HTS leads are located. The behavior of the HTS leads in a magnetic field depends strongly on the HTS material used for the leads and the temperature of the cooler first stage temperature. The HTS leads can be specified to operate at the maximum current for the magnet. This report shows how the HTS leads can be specified for use the MICE magnets. MICE magnets take from 1.3 hours (the tracker solenoids) to 3.7 hours (the coupling magnet) to charge to the highest projected operating currents. If the power fails, the cooler and the upper ends of the HTS leads warm up. The question is how one can discharge the magnet to protect the HTS leads without quenching the MICE magnets. This report describes a method that one can use to protect the HTS leads in the event of a power failure at the Rutherford Appleton Laboratory (RAL).
Trusted Storage over Untrusted Networks (2010)

We consider distributed storage over two untrusted networks, whereby coding is used as a means to achieve a prescribed level of confidentiality. The key idea is to exploit the algebraic structure of the Vandermonde matrix to mix the input blocks, before they are stored in different locations. The proposed scheme ensures that eavesdroppers with access to only one of the networks are unable to decode any symbol even if they are capable of guessing some of the missing blocks. Information-theoretic techniques allow us to quantify the achievable level of confidentiality. Moreover, the proposed approach is shown to offer low complexity and optimal rate.
Risk, challenge and safety in outdoor play: pedagogical and regulatory tensions (2010)

Early Childhood services are becoming an increasingly significant part of children’s lives. As such they offer vital opportunities for children to engage in physically challenging active play in a safe and secure environment. However, in an increasingly ‘risk averse’ society an over-emphasis on safety has seen such play opportunities eroded. This qualitative study explored Early Childhood practitioners’ (n = 17) beliefs about risk-taking and their provision of ‘risky’ play opportunities in the outdoor environment. The findings suggest that from a pedagogical perspective, practitioners believe opportunities for risk-taking are important for all aspects of children’s development however the regulatory environment places constraints on their ability to provide sufficiently challenging experiences. The research findings support the call for more flexible enforcement of regulations to allow practitioners to use their professional knowledge to make informed decisions in risk situations.
Oral Rehydration Solution Containing a Mixture of Non-Digestible Carbohydrates in the Treatment of Acute Diarrhea: A Multicenter Randomized Placebo Controlled Study on Behalf of the ESPGHAN Working Group on Intestinal Infections (2004)

In boys with acute non-cholera diarrhea with mild to moderate dehydration a mixture of non-digestible carbohydrates was ineffective as an adjunct to oral rehydration therapy.
[Expression and significance of TGF-beta1 and HSP70 in human laryngeal squamous cell carcinoma]. (2007)

TGF-beta1 and HSP70 play an important role in malignant behaviors of human laryngeal carcinoma.
Increased Aspartate Aminotransferase Activity of Serum after in Vitro Supplementation with Pyridoxal Phosphate (1973)

Abstract We examined the effect of pyridoxal phosphate supplementation on the apparent aspartate aminotransferase (EC 2.6.1.1.) activity of human serum. Supplementation by 25 µmol/liter effected an average increase of 16% in the results for kinetic assay. The increase was not the result of increased enzymatic or nonenzymatic blanks, and, within a small range, sample dilution had no significant effect. Part of the increase was attributable to the enzyme being protected against the loss of activity that occurs during preincubation with L-aspartate. A similar increase was not demonstrated in a two-point colorimetric method, perhaps because of the short reaction time, without preincubation, and the initial presence of both substrates in the assay. We attempted to Correlate such stimulation of aminotransferase activity and the patient’s diagnosis or treatment. Pyridoxal phosphate should be included in the reaction mixture when aspartate aminotransferase activity is being measured clinically
A novel Cookson‐type reagent for enhancing sensitivity and specificity in assessment of infant vitamin D status using liquid chromatography/tandem mass spectrometry (2013)

We developed DAPTAD for enhancing the sensitivity and specificity of the LC/ESI-MS/MS assay of 25(OH)D3. Our new method using DAPTAD can reduce the overestimation of the 25(OH)D3 levels, and will prove helpful in the diagnosis of vitamin D deficiency in infants.
Analysis of Concurrent, Coupled, and Correlated Processes (2009)

This chapter introduces the notion of using multiple channels of biomedical signals to obtain information on concurrent, coupled, and correlated phenomena with the aim of obtaining an improved understanding of physiological systems or obtaining reference signals for various purposes. The main point to note is that physiological systems should be studied from various approaches in order to gain multifaceted information. Most biological processes within the body are not independent of one another; rather, they are mutually correlated and bound together by physical or physiological control and communication phenomena. Analyzing any single process without due attention to others that are concurrent, coupled, or correlated with the process may provide only partial information and pose difficulties in the comprehension of the process. An investigator should explore the system or process of interest from all possible angles and use multidisciplinary approaches to identify several potential sources of information. The signals so obtained may be electrical, mechanical, biochemical, or physical, among the many possibilities, and may exhibit interrelationships confounded by peculiarities of transduction, time delays, multipath transmission or reflection, waveform distortions, and filtering effects that may need to be accounted for in their simultaneous analysis.
Spatiotemporal heterogeneity of phytoplankton diversity and its relation to water environmental factors in the southern waters of Miaodao Archipelago,China (2016)

到水质量在浮游植物上由人为的活动和它的影响影响了的学习，在表面的差异 Miaodao 群岛，在浮游植物社区的空间与时间的变化和包围 Miaodao 的五个南部的岛的表面水的环境性质流水群岛被调查，基于从2012年11月进行到2013年8月的季节的领域调查。在调查期间，从 3 个组的 109 浮游植物种类的一个总数在 Miaodao 群岛， 77 是硅藻的南部的水里被识别， 29 是 dinoflagellates，并且 3 是 chrysophytes。种类数字在冬季(73 ) 是更高的，在秋天(70 ) 节制，但是在夏天(31 ) 和春天(27 ) 降低。在秋天(5.92 ) 和冬季(4.28 ) 的种类丰富索引在夏天(2.83 ) 和春天(1.41 ) 比那高。Shannon 牛肉熏香肠差异索引在秋天(2.82 ) 高，到冬季(1.99 ) 和夏天(1.92 ) 列在后面，并且在春天(0.07 ) 低。在秋天(0.46 ) 和夏天(0.39 ) 的种类平均索引在冬季(0.32 ) 和春天(0.02 ) 比那高。根据主要部件分析( PCA )和冗余性分析( RDA )，分别地，我们在冬季在春天，在夏天的货到付款，在秋天的 pH ，和咸度和油污染物质发现了那溶解的无机的氮(吵闹)和化学的氧需求(货到付款)与浮游植物差异的分发显示出最强壮的协会。Miaodao 群岛的南部的水的空间异质是相当明显的，并且三个地区，即，东北、西南、内部岛的水区域，被簇分析(CA ) 基于关键环境变量识别。
Research on warning model of urban road collapsing based on GPR and fuzzy theory (2017)

In recent years, accidents of urban road collapsing occur frequently, which not only cause considerable economic losses, but also the casualties. For the various problems and potential security risks brought by urban road collapsing, this paper analyzes the factors of urban road collapsing and a new warning method based on dynamic tracking is put forward. And a warning model of hazard grade of urban road diseases is established based on GPR and the theory of fuzzy comprehensive evaluation. An application experiment has been conducted to the Binhe road and Huicui road of Zhongmu County to verify the new warning model. The result shows that: the warning model can effectively predict the hazard grade of urban road diseases in practical application, and provide effective technical support for the road maintenance and engineering treatment.
Topical WIN55212-2 Alleviates Intraocular Hypertension in Rats Through a CB1 Receptor Mediated Mechanism of Action (2008)

In a chronic ocular hypertensive rat model, topically applied WIN is an effective, nontoxic ocular hypotensive agent with no hemodynamic side-effects. This effect was predominantly CB1 receptor mediated, but some CB2 contribution could not be ruled out.
Chemistry of acetylenic ethers XLVII: Preparation of α‐ketols from ethoxyethynylcarbinols (1960)

Abstract A method is described for converting ethoxyethynylcarbinols I into α‐ketols V, via the intermediate products II to IV inclusive. The synthesis occurs stereospecifically and, starting from the ethoxy‐ethynylcarbinol VII, derived from 3β‐acetoxyandrost‐5‐en‐17‐one VI, affords almost exclusively 3β,21‐dihydroxypregn‐5‐en‐20‐one XI in about 50% yield.
Isolation and expression of a cDNA encoding a male-specific rat sulfotransferase that catalyzes activation of N-hydroxy-2-acetylaminofluorene. (1993)

A cDNA (ST1C1 cDNA) encoding a N-hydroxyarylamine sulfotransferase (HAST-I) was isolated from a liver cDNA library of a male adult rat and was expressed in COS-1 cells. ST1C1 cDNA (1363 base pairs) encoded a protein of 304 amino acids with a molecular mass of 35,768 daltons, which shared 50.7 and 46.1% sequence identity with rat aryl (ST1A1 (PST-1)) and estrogen (rOST) sulfotransferases, respectively. N-terminal amino acid sequences of three digested polypeptide fragments of HAST-I were completely identical with two portions of the ST1C1 amino acid sequence. The profile of age- and sex-related expression of ST1C1 mRNA was quite consistent with changes in the sulfating activity of N-hydroxyarylamine and HAST contents in rat livers. ST1C1 expressed in COS-1 cells catalyzed a sulfation of N-hydroxy-2-acetylaminofluorene (N-OH-AAF) at a rate of 4.98 nmol/mg of protein/min and mediated PAPS (3'-phosphoadenosine-5'-phosphosulfate)-dependent DNA binding of N-OH-AAF. Although ASTIV was believed to be responsible for the activation of N-OH-AAF, ST1A1 encoding an arylsulfotransferase ASTIV, showed only a marginal activity in a sulfation and covalent binding of N-OH-AAF. These data clearly indicate that ST1C1 cDNA codes a new form of a male-dominant sulfotransferase (HAST) responsible for the bioactivation of N-hydroxyarylamines in rat livers.
Compiling for distributed memory architectures (1994)

The lack of high-level languages and good compilers for parallel machines hinders their widespread acceptance and use. Programmers must address issues such as process decomposition, synchronization, and load balancing. We have developed a parallelizing compiler that, given a sequential program and a memory layout of its data, performs process decomposition while balancing parallelism against locality of reference. A process decomposition is obtained by specializing the program for each processor to the data that resides on that processor. If this analysis fails, the compiler falls back to a simple but inefficient scheme called run-time resolution. Each process's role in the computation is determined by examining the data required for execution at run-time. Thus, our approach to process decomposition is data-driven rather than program-driven. We discuss several message optimizations that address the issues of overhead and synchronization in message transmission. Accumulation reorganizes the computation of a commutative and associative operator to reduce message traffic. Pipelining sends a value as close to its computation as possible to increase parallelism. Vectorization of messages combines messages with the same source and the same destination to reduce overhead. Our results from experiments in parallelizing SIMPLE, a large hydrodynamics benchmark, for the Intel iPSC/2, show a speedup within 60% to 70% of handwritten code.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Immunomodulating capacity of kefir (2005)

Kefir is a fermented milk produced by the action of lactic acid bacteria, yeasts and acetic acid bacteria, trapped in a complex matrix of polysaccharides and proteins. Beyond its inherent high nutritional value as a source of proteins and calcium, kefir has a long tradition of being regarded as good for health in countries where it is a staple in the diet. However, published human or animal feeding trials to substantiate this view are not numerous. The aim of this work was to determine the immunomodulating capacity of kefir on the intestinal mucosal immune response in mice and to demonstrate the importance of dose and cell viability on this response. BALB/c mice were fed with commercial kefir ad libitum (diluted 1/10, 1/50, 1/100 or 1/200) or pasteurized kefir (diluted 1/6, 1/10, 1/50, 1/100) for 2, 5 or 7 consecutive days. At the end of each feeding period, the bacterial translocation assay was performed in the liver. Small intestine structure was studied by haematoxilin-eosin staining and light microscopy. The number of IgA+ and IgG+ cells was also determined. For the functional doses chosen, cytokines (IL-2, IL-4, IL-6, IL-10, IL-12, TNF-alpha and IFN-gamma) were determined. Kefir and pasteurized kefir were able to modulate the mucosal immune system in a dose-dependent manner. Kefir was administred 10-times more diluted than pasteurized kefir, but it induced an immunomodulation of similar magnitude, indicating the importance of cell viabilty. The results suggest that a Th1 response was controlled by Th2 cytokines induced by kefir feeding. Pasteurized kefir would induce both Th2 and Th1 responses. This is the first study in vivo regarding the mechanisms involved in the immunomodulating capacity of the oral administration of kefir containing viable or heat-inactivated bacteria at different doses.
Ethyl (4‐<i>N</i>‐acylaminopyridin‐3‐yl)glyoxylate and 5‐azaisatin as new synthons for a route to various new polyheterocycles (1997)

Abstract From 4‐ N ‐protected‐aminopyridines which were functionalized at their 3‐position, 5‐azaisatin and equivalent synthons where obtained. Via the use of the Pfitzinger reaction, these compounds provided an easy route to new and various polyheterocyclic compounds.
The cancer-testis Sp17 and ASP are expressed in the ciliated hepatic foregut cysts (2013)

Meeting abstracts Although ciliated hepatic foregut cysts (CHFCs) are retained benign lesions, a case of squamous cell metaplasia and three cases of squamous cell carcinoma arising from CHFCs has been reported. The potential of malignant transformation make it necessary the identification of new
Database Anomalous Activities - Detection and Quantification (2013)

The disclosure of sensitive data to unauthorized entities is a critical issue for organizations. Timely detection of data leakage is crucial to reduce possible damages. Therefore, breaches should be detected as early as possible, e.g., when data are leaving the database. In this paper, we focus on data leakage detection by monitoring database activities. We present a framework that automatically learns normal user behavior, in terms of database activities, and detects anomalies as deviation from such behavior. In addition, our approach explicitly indicates the root cause of an anomaly. Finally, the framework assesses the severity of data leakages based on the sensitivity of the disclosed data.
A Driving Method of Pixel Circuit Using a-IGZO TFT for Suppression of Threshold Voltage Shift in AMLED Displays (2017)

A driving method of pixel circuit using amorphous indium gallium zinc oxide (a-IGZO) thin-film transistor (TFT) is proposed to improve the image quality of active matrix light-emitting diode displays. The proposed pixel circuit employs a diode-connected structure to compensate for variation in threshold voltage (Vth) of the a-IGZO TFT. In addition, the proposed driving method adopts negative bias annealing to suppress the Vth shift. The annealing time is optimized based on the experimental observation of the minimum Vth shift. After a stress time of 30000 s, the measurement results show that the Vth shift is reduced by 29.6%, using an optimized annealing time of 5% of one frame time. In addition, the maximum deviation in the emission current using the proposed driving method was measured to be less than 4.32% after a stress time of 30 000 s.
Pillowing Doublets: Refining a Mesh to Ensure That Faces Share At Most One Edge (1995)

Occasionally one may be confronted by a hexahedral or quadrilateral mesh containing doublets, two faces sharing two edges. In this case, no amount of smoothing will produce a mesh with agreeable element quality: In the planar case, one of these two faces will always have an angle of at least 180 degrees between the two edges. We describe a robust scheme for refining a hexahedral or quadrilateral mesh to separate such faces, so that any two faces share at most one edge. Note that this also ensures that two hexahedra share at most one face in the three dimensional case. We have implemented this algorithm and incorporated it into the CUBIT mesh generation environment developed at Sandia National Laboratories. 1. Introduction In a quadrilateral or hexahedral mesh, a doublet is defined as two quadrilateral faces that share two edges. When this occurs in a mesh, there is something fundamentally wrong with the local connectivity: In any geometric embedding of these faces, at least one face ...
Brotherton v. Cleveland. (1991)

The U.S. Court of Appeals for the Sixth Circuit reversed the lower trial court and allowed a decedent's family to pursue a claim under the federal constitution for wrongful removal of the decedent's corneas. The hospital had documented Deborah Brotherton's refusal of any anatomical gift from her husband's body, but it failed to notify the coroner of her wishes. Furthermore, the coroner did not inquire about any objection to anatomical gifts before allowing an eyebank technician to remove Steven Brotherton's corneas. Deborah Brotherton alleged wrongful deprivation of property under the due process clause. Based on state law allowing her a possessory right to the body, a right to control disposition of the body, and a claim for mishandling of the body, the court found the interest of the wife as next of kin in her dead husband's body to be substantial, and thus protected by the Fourteenth Amendment, even if it is not a property interest or quasi-property interest.
The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia (2015)

Cystic fibrosis (CF), a genetic disease caused by mutations in the CFTR gene, is a life-limiting disease characterized by chronic bacterial airway infection and severe inflammation. Some CFTR mutants have reduced responsiveness to cAMP/PKA signaling; hence, pharmacological agents that elevate intracellular cAMP are potentially useful for the treatment of CF. By inhibiting cAMP breakdown, phosphodiesterase (PDE) inhibitors stimulate CFTR in vitro and in vivo. Here, we demonstrate that PDE inhibition by RPL554, a drug that has been shown to cause bronchodilation in asthma and chronic obstructive pulmonary disease (COPD) patients, stimulates CFTR-dependent ion secretion across bronchial epithelial cells isolated from patients carrying the R117H/F508del CF genotype. RPL554-induced CFTR activity was further increased by the potentiator VX-770, suggesting an additional benefit by the drug combination. RPL554 also increased cilia beat frequency in primary human bronchial epithelial cells. The results indicate RPL554 may increase mucociliary clearance through stimulation of CFTR and increasing ciliary beat frequency and thus could provide a novel therapeutic option for CF.