gebhart/patrepeval huggingface dataset:
IGF-I–Stimulated Glucose Transport in Human Skeletal Muscle and IGF-I Resistance in Obesity and NIDDM (1990)

Based on the observation that insulinlike growth factor I (IGF-I) can stimulate glucose utilization in nondiabetic subjects and that the action of the IGF-I receptor is normal in the skeletal muscle of patients with non-insulin-dependent diabetes mellitus (NIDDM), it seems possible that IGF-I might provide an effective acute treatment for the hyperglycemia of NIDDM. Using our recently developed in vitro human muscle preparation, we investigated the hypothesis that IGF-I might be an effective alternative to insulin in stimulating glucose transport in diabetic muscle. Abdominal muscle samples from nonobese nondiabetic, obese nondiabetic, and obese NIDDM patients were obtained during elective abdominal surgery. Plasma levels of IGF-I in diabetic patients were lower than those in either of the nondiabetic groups. Binding studies with wheat-germ-agglutinin-chromatography-purified receptors demonstrated the presence of IGF-I receptors in human muscle, with IGF-I binding being approximately 24% that of insulin. There was no change in IGF-I binding in muscle from obese or diabetic subjects, and the structural characteristics of the IGF-I receptor were not altered, as determined by electrophoretic mobility. IGF-I stimulated glucose transport approximately twofold in incubated muscle from control subjects, but there was no IGF-I stimulation of transport in muscle from obese subjects with or without NIDDM. These results confirm a previous report that human muscle contains receptors for IGF-I and demonstrate for the first time that IGF-I can stimulate glucose transport in human muscle. However, muscle from obese subjects with or without NIDDM is resistant to the action of IGF-I.
Microfluidic MEMS hand-held flow cytometer (2011)

Due to a number of recent technological advances, a hand-held flow cytometer can be achieved by use of semiconductor illuminators, optical sensors (all battery powered) and sensitive cell markers such as immuno-quantum dot (Qdot) labels. The specific application described is of a handheld blood analyzer that can quickly process a drop of whole, unfractionated human peripheral blood by real-time, on-chip magnetic separation of white blood cells (WBCs) and red blood cells (RBCs) and further fluorescence analysis of Qdot labeled WBC subsets. Various microfluidic patterns were fabricated in PDMS and used to characterize flow of single cells and magnetic deflection of magnetically labeled cells. An LED excitation, avalanche photodiode detection system (SensL Technologies, Ltd., Cork, Ireland) was used for immuno-Qdot detection of WBC subsets. A static optical setup was used to determine the sensitivity of the detection system. In this work we demonstrate: valve-less, on-chip magnetic sorting of immunomagnetically labeled white blood cells, bright Qdot labeling of lymphocytes, and counting of labeled white blood cells. Comparisons of these results with conventional flow cytometric analyses are reported. Sample preparation efficiency was determined by labeling of isolated white blood cells. Appropriate flow rates were determined for optical detection and confirmed with flowing particles. Several enabling technologies required for a truly portable, battery powered, hand-held flow cytometer for use in future point-of-care diagnostic devices have been demonstrated. The combining of these technologies into an integrated handheld instrument is in progress and results on whole blood cell analysis are to be reported in another paper.
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016)

There is strong evidence that chromoscopy enhances the detection of neoplasia in the colon and rectum. People with neoplastic polyps, particularly those with multiple polyps, are at increased risk of developing colorectal cancer. Such lesions, which presumably would be missed with conventional colonoscopy, could contribute to the interval cancer numbers on any surveillance programme.
Highly Enantioselective Thiourea‐Catalyzed Nitro‐Mannich Reactions (2004)

Bald „privilegiert“? Durch Modifizierung Harnstoff-basierter Strecker-Katalysatoren ließ sich ein neuer und hoch effektiver enantioselektiver Katalysator für die Nitro-Mannich-Reaktion identifizieren. Die Produkte werden mit hoher Enantiomerenreinheit und einem Diastereomerenverhältnis bis 16:1 erhalten. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2005/z461814_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Achieving efficient channel utilization using dynamic coverage control in IEEE 802.11 (2005)

IEEE 802.11 wireless LAN protocol uses fixed transmission power. It does not consider a power control mechanism based on the distance between the transmitter and the receiver in order to improve overall channel utilization. In the home environment, where stations generally lie around an access point (AP), the AP might use transmission power more than it needs. And, wireless LAN stations may require different minimum desired receiving power. If there are many adjacent BSSs (base service sets) in a densely populated WLAN area, e.g., multiple dwelling homes or hotspots, they might cause RF interference to one another. In this paper, we focus on the improvement of aggregate utilization by mitigating RF interference among BSSs. We show that RF interference can be reduced by controlling transmission power of APs. The reduced interference then leads to an increased aggregate throughput of the system, i.e., efficient resource utilization.
A Novel Phenotypic Pattern in X-Linked Inheritance: Craniofrontonasal Syndrome Maps to Xp22 (1997)

Craniofrontonasal syndrome (CFNS, OMIM 304110) is a distinctive genetic disorder whose main clinical manifestations include coronal synostosis, widely spaced eyes, clefting of the nasal tip and various skeletal anomalies. CFNS originally was thought to be transmitted as an autosomal dominant trait, but recent studies suggest that it is X-linked dominant, whereby all daughters of males are affected, whereas none of their sons are affected. Here we report data confirming that CFNS is X-linked, mapping to a 13 cM interval in Xp22 with a maximum two-point lod score of 3.9 (theta = 0) at DXS8022 and a multipoint lod score of 5.08 at DXS1224. Detailed phenotypic analysis shows that females are more severely affected than males, a highly unusual characteristic for an X-linked disorder. CFNS represents the first multiple congenital anomaly syndrome with this unusual phenotypic pattern of X-linked inheritance.
The Hmong Qeej: Speaking to the Spirit World (1997)

This investigation focuses on the unique communicativeability of the Hmong qeej, a free-reed multiple pipe musicalinstrument. Other forms of the qeej are used by variousSoutheast Asian cultures, but only the Hmong appear to use itto communicate in words with the spirit world.This study is based on oral interviews with Hmong qeejplayers, focusing on one master qeej player. Discussionreviews the origin legend of the qeej, legendary powers ofthe instrument, the mystery of the qeej language, training ofa qeej player, qualifications of a master qeej player, genreof qeej songs, the role of the qeej in the funeral ceremony,and the qeej as the consumate Hmong cultural identifier.
Fractal dimension of gas-evaporated Co aggregates: Role of magnetic coupling (1988)

Aggregated Co particles were produced by inert-gas evaporation in Ar. A fractal dimension ${\mathrm{D}}_{\mathrm{f}}$ was extracted from electron micrographs; it was strongly dependent on the mean particle radius R\ifmmode\bar\else\textasciimacron\fi{}. We found 1.9\ensuremath{\lesssim}${\mathrm{D}}_{\mathrm{f}}$\ensuremath{\lesssim}2.05 at R\ifmmode\bar\else\textasciimacron\fi{}\ensuremath{\lesssim}8 nm and 1.35\ensuremath{\lesssim}${\mathrm{D}}_{\mathrm{f}}$\ensuremath{\lesssim}1.6 at R\ifmmode\bar\else\textasciimacron\fi{}\ensuremath{\gtrsim}8 nm. The low ${\mathrm{D}}_{\mathrm{f}}$ can be understood as an effect of magnetic dipole interaction, leading to chainlike aggregates when the critical size for ferromagnetism in Co particles is exceeded. The experimental values are in good agreement with recent computer simulations.
Dose-Dense Chemotherapy for Node-Positive Breast Cancer (2005)

Letters1 February 2005Dose-Dense Chemotherapy for Node-Positive Breast CancerMarc L. Citron, MDMarc L. Citron, MDFrom Albert Einstein College of Medicine, Lake Success, NY 11042.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-3-200502010-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In the 2004 Update in Oncology (1), Dr. Steven H. Stein discussed a study by the U.S. Breast Cancer Intergroup on dose-dense therapy for node-positive breast cancer (2) and questioned the expense of filgrastim support. Dose-dense chemotherapy increases the dose intensity of the adjuvant regimen by delivering standard-dose chemotherapy with shorter intervals between the cycles. Filgrastim support enables the delivery of dose-dense chemotherapy and reduces the risk for neutropenia and its complications (3). Although the U.S. Breast Cancer Intergroup Trial C9741 acknowledged the added cost, concerns over the added expense must be weighed against the savings that ...References1. Stein SH. Update in oncology. Ann Intern Med. 2004;141:454-9. [PMID: 15381519] LinkGoogle Scholar2. Citron ML, Berry DA, Cirrincione C, Hudis C, Winer EP, Gradishar WJ, et al. Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol. 2003;21:1431-9. [PMID: 12668651] MedlineGoogle Scholar3. Citron ML. Dose density in adjuvant chemotherapy for breast cancer. Cancer Invest. 2004;22:555-68. [PMID: 15565814] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Albert Einstein College of Medicine, Lake Success, NY 11042.Note: Dr. Citron is the principal investigator of the U.S. Breast Cancer Intergroup Trial C9741. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoUpdate in Oncology Steven H. Stein Metrics Cited ByA Neoadjuvant Chemotherapy Trial for Early Breast Cancer is Impacted by COVID-19: Addressing Vaccination and Cancer Trials Through Education, Equity, and OutcomesAdjuvant Chemotherapy for Early Breast Cancer in the ElderlyCarboplatin plus Gemcitabine Repeating Doublet Therapy in Recurrent Breast CancerSafety and efficacy of once-per-cycle pegfilgrastim in support of ABVD chemotherapy in patients with Hodgkin lymphoma 1 February 2005Volume 142, Issue 3Page: 227KeywordsBreast cancerCancer treatmentChemotherapyForecastingHospitalizationsNeutropenia ePublished: 1 February 2005 Issue Published: 1 February 2005 CopyrightCopyright © 2005 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
<i>Know Thy Nano Neighbor</i>. Plasmonic <i>versus</i> Electron Charging Effects of Metal Nanoparticles in Dye-Sensitized Solar Cells (2012)

Neighboring metal nanoparticles influence photovoltaic and photocatalytic behavior of semiconductor nanostructures either through Fermi level equilibration by accepting electrons or inducing localized surface plasmon effects. By employing SiO(2)- and TiO(2)-capped Au nanoparticles we have identified the mechanism with which the performance of dye-sensitized solar cells (DSSC) is influenced by the neighboring metal nanoparticles. The efficiency of an N719 dye-sensitized solar cell (9.3%) increased to 10.2% upon incorporation of 0.7% Au@SiO(2) and to 9.8% upon loading of 0.7% Au@TiO(2) nanoparticles. The plasmonic effect as monitored by introducing Au@SiO(2) in DSSC produces higher photocurrent. However, Au nanoparticles undergo charge equilibration with TiO(2) nanoparticles and shift the apparent Fermi level of the composite to more negative potentials. As a result, Au@TiO(2) nanoparticle-embedded DSSC exhibit higher photovoltage. A better understanding of these two effects is crucial in exploiting the beneficial aspects of metal nanoparticles in photovoltaics.
Control of the Optical Properties of Quantum Dots by Surface Coating with Calix[<i>n</i>]arene Carboxylic Acids (2006)

A new method for the control of the optical properties of quantum dots (QDs) has been developed using calix[n]arene carboxylic acids (1-3) as surface coating agents for QDs. The calixarene coating of CdSe/ZnS QDs was easily performed in tetrahydrofuran at room temperature. Deprotonation of the carboxyl groups of the calixarene derivatives surrounding the QDs resulted in highly fluorescent water-soluble QDs. The emission peak of the calixarene-coated QDs shifted to longer wavelengths depending on the oligomer size of the calix[n]arene derivative used for the surface coating. Although the red shift of the emission peak decreases with the increase in the particle size of QDs, this surface coating method is useful for the preparation of multi-colored water-soluble QDs from a single-colored hydrophobic QD.
Recycling Tires? Reversible Crosslinking of Poly(butadiene) (2015)

Furan-modified poly(butadiene) prepared by the thiol-ene click reaction is crosslinked with bismaleimides through the Diels-Alder reaction, giving rise to a novel recyclable elastomer. This is possible because of the thermal reversibility of the adducts responsible for the formation of the network. The use of this strategy provides the possibility to produce recyclable tires.
Synthesis and catalytic activity of carbon supported copper nanoparticles for the synthesis of aryl nitriles and 1,2,3-triazoles (2014)

Various substituted aryl nitrile and 1,2,3-triazole derivatives were prepared by using carbon supported copper nanoparticles (C/Cu NPs) as a heterogeneous catalyst under ligand-free conditions, which provided good to excellent yields.
The effect of exercise on mobilization of hematopoietic progenitor cells involved in the repair of sciatic nerve crush injury [RETRACTED] (2012)

Object Mobilization of hematopoietic progenitor cells (HPCs) from bone marrow involved in the process of peripheral nerve regeneration occurs mostly through deposits of CD34(+) cells. Treadmill exercise, with either differing intensity or duration, has been shown to increase axon regeneration and sprouting, but the effect of mobilization of HPCs on peripheral nerve regeneration due to treadmill exercise has not yet been elucidated. Methods Peripheral nerve injury was induced in Sprague-Dawley rats by crushing the left sciatic nerve using a vessel clamp. The animals were categorized into 2 groups: those with and without treadmill exercise (20 m/min for 60 minutes per day for 7 days). Cytospin and flow cytometry were used to determine bone marrow progenitor cell density and distribution. Neurobehavioral analysis, electrophysiological study, and regeneration marker expression were investigated at 1 and 3 weeks after exercise. The accumulation of HPCs, immune cells, and angiogenesis factors in injured nerves was determined. A separate chimeric mice study was conducted to assess CD34(+) cell distribution according to treadmill exercise group. Results Treadmill exercise significantly promoted nerve regeneration. Increased Schwann cell proliferation, increased neurofilament expression, and decreased Schwann cell apoptosis were observed 7 days after treadmill exercise. Elevated expression of S100 and Luxol fast blue, as well as decreased numbers of vacuoles, were identified in the crushed nerve 3 weeks after treadmill exercise. Significantly increased numbers of mononuclear cells, particularly CD34(+) cells, were induced in bone marrow after treadmill exercise. The deposition of CD34(+) cells was abolished by bone marrow irradiation. In addition, deposits of CD34(+) cells in crushed nerves paralleled the elevated expressions of von Willebrand factor, isolectin B4, and vascular endothelial growth factor. Conclusions Bone marrow HPCs, especially CD34(+) cells, were able to be mobilized by low-intensity treadmill exercise, and this effect paralleled the significant expression of angiogenesis factors. Treadmill exercise stimulation of HPC mobilization during peripheral nerve regeneration could be used as a therapy in human beings.
Ethylene Production by<i>Botrytis cinerea</i>In Vitro and in Tomatoes (2002)

A laser-based ethylene detector was used for on-line monitoring of ethylene released by the phytopathogenic fungus Botrytis cinerea in vitro and in tomato fruit. Ethylene data were combined with the results of a cytological analysis of germination of B. cinerea conidia and hyphal growth. We found that aminoethoxyvinylglycine and aminooxyacetic acid, which are competitive inhibitors of the 1-aminocyclopropane-1-carboxylic acid pathway, did not inhibit the ethylene emission by B. cinerea and that the fungus most likely produces ethylene via the 2-keto-4-methylthiobutyric acid pathway. B. cinerea is able to produce ethylene in vitro, and the emission of ethylene follows the pattern that is associated with hyphal growth rather than the germination of conidia. Ethylene production in vitro depended on the L-methionine concentration added to the plating medium. Higher values and higher emission rates were observed when the concentration of conidia was increased. Compared with the ethylene released by the fungus, the infection-related ethylene produced by two tomato cultivars (cultivars Money Maker and Daniela) followed a similar pattern, but the levels of emission were 100-fold higher. The time evolution of enhanced ethylene production by the infected tomatoes and the cytological observations indicate that ethylene emission by the tomato-fungus system is not triggered by the ethylene produced by B. cinerea, although it is strongly synchronized with the growth rate of the fungus inside the tomato.
Defending systems Against Tilt DDoS attacks (2011)

How to effectively resist DoS/DDoS (Distributed Denial of Service) attacks is one of the primary issues for Internet security. This paper studies non-invasive types of DoS/DDoS attacks, which attacks against servers via protocol-compliant and legitimate application-layer requests. Attackers use some special service requests, which require high processing complexity, to overwhelm the servers' resources. This paper presents an effective defense system namely DAT: Defense system Against Tilt DDoS attacks. Through analyzing each client's features, such instant traffic volume, session behavior, and so on. DAT schedules requests and decides whether to activate the defense mechanisms or not. The DAT is capable of effectively suppressing DoS/DDoS attacks, so that the protected server cluster is able to operate normally even under attacking. Simulation results show that DAT concentrates to serve legitimate users instead of wasting resources on malicious users.
Overview of the Pathogenesis of ANCA-Associated Vasculitis (2015)

Patients with active AAV have ongoing asynchronous onsets of countless acute lesions, with each lesion evolving through stereotypical phases within 1 or 2 weeks. Induction of remission results in termination of new waves of acute lesions and allows all lesions to progress to scarring or resolution.
Measured mutual coupling between linearly tapered slot antennas (1997)

Mutual coupling between two linearly tapered slot antennas arranged in coplanar as well as stacked configurations has been measured. Results indicate that mutual coupling level generally decreases with antenna separations and varies with dielectric constant, and antenna lengths.
Comparison of Aphids Trapped on Vertical Sticky Board and Cylindrical Aphid Traps and Correlation with Watermelon Mosaic Virus 2 Incidence1 (1976)

Journal Article Comparison of Aphids Trapped on Vertical Sticky Board and Cylindrical Aphid Traps and Correlation with Watermelon Mosaic Virus 2 Incidence Get access W. C. Adlerz W. C. Adlerz University of Florida IFAS, Agricultural Research Center, Leesburg 32748 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 69, Issue 4, 1 August 1976, Pages 495–498, https://doi.org/10.1093/jee/69.4.495 Published: 01 August 1976 Article history Received: 29 March 1976 Published: 01 August 1976
An Adaptive Medium Access Parameter Prediction Scheme for IEEE 802.11 Real-Time Applications (2017)

Multimedia communications have experienced an unprecedented growth due mainly to the increase in the content quality and the emergence of smart devices. The demand for these contents is tending towards wireless technologies. However, these transmissions are quite sensitive to network delays. Therefore, ensuring an optimum QoS level becomes of great importance. The IEEE 802.11e amendment was released to address the lack of QoS capabilities in the original IEEE 802.11 standard. Accordingly, the Enhanced Distributed Channel Access (EDCA) function was introduced, allowing it to differentiate traffic streams through a group of Medium Access Control (MAC) parameters. Although EDCA recommends a default configuration for these parameters, it has been proved that it is not optimum in many scenarios. In this work a dynamic prediction scheme for these parameters is presented. This approach ensures an appropriate traffic differentiation while maintaining compatibility with the stations without QoS support. As the APs are the only devices that use this algorithm, no changes are required to current network cards. The results show improvements in both voice and video transmissions, as well as in the QoS level of the network that the proposal achieves with regard to EDCA.
Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of steroids (1969)

The natural abundance ^(13)C resonance spectra of a variety of sterols and steroidal hormones have been determined at 15.1 MHz. The chemical shifts of the carbons in these substances were found to span on the order of 200 ppm and for most steroids with the aid of complete proton decoupling it was possible to resolve all of the carbon resonances one from the other. It has also been possible by using specific single-frequency and off-resonance proton decoupling, hydroxyl acetylation effects on chemical shifts, deuteration, and substituent influences in analogous\ncompounds to make self-consistent and unambiguous assignments of nearly all of the resonances encountered.\nThe carbon resonances are in general far more informative than proton resonances for structural analysis of steroids.
Error resilient video transmission with adaptive stream-shuffling and bi-directional error concealment (2002)

This paper proposes a set of resident algorithms in conjunction with the H.263 standard to support video transmission over mobile radio channels. Specifically, an adaptive stream-shuffling scheme is proposed to mitigate the effects of burst-errors in mobile channels, while an efficient error detection and a bi-directional error concealment algorithm, which exploits the inherent correlation and the error resilient diversity of PB coding mode in an H.263 coded bit stream, are effectively incorporated. Simulations show that this set of algorithms can achieve an efficient and effective video transmission in most of wireless environments.