gebhart/patrepeval huggingface dataset:
A theoretical and experimental study of the series-connected magnetic amplifier (1949)

The mathematical analysis of magnetic amplifiers is made difficult by the non-linear characteristic of the iron. By simplifying the problem (neglecting leakage reactance and assuming an ideal B/H characteristic) a solution can be obtained which shows that the steadystate and transient operation of an amplifier having one of the two basic circuits analysed, depend on only three dimensionless coefficients. This solution leads to simple semi-graphical methods of determining the steady-state current and flux waveforms, and the response to sudden changes in input; satisfactory agreement between experimental results and theory has been obtained.Improvements in core characteristics have led to a simplified method of designing amplifier windings, and by special circuits amplifier delays have been reduced in the ratio of about 10:1.
Improved electrode for electroretinography. (1979)

Corneal electrodes useful for clinical electroretinography require topical anesthesia, interfere with vision, can abrade, and are not well accepted by most children and many adults. A low mass conductive thread, corneal (DTL) electrode is described and comparatively tested against the Burian-Allen electrode. The DTL electrode was found to have few of the limitations of the hard contact lens electrode. Furthermore, the DTL electrode signal quality was comparable to that of the Burian-Allen electrode and provided less between-patient variability.
Dissipative Particle Dynamics (DPD) Study of Crude Oil−Water Emulsions in the Presence of a Functionalized Co-polymer (2010)

This work presents a theoretical study of the effects of different molecular weights of a triblock co-polymer ethylene oxide/propylene oxide/ethylene oxide, bifunctionalized with ethalamine, on the coalescence of water drops imbibed in a crude oil environment. The polymer/crude oil/water (PCW) time evolution of the emulsion was simulated using the framework of the dissipative particle dynamics (DPD) technique. The bead−bead interactions of the molecular components were calculated using the correlation between the solubility parameter, χij, of the Flory−Huggins theory and the conservative force parameter, aij. The solubility parameter was obtained from atomic molecular models of prototype molecules of saturates, aromatics, resins, asphaltenes, and the triblock co-polymer, through the blend methodology. The dynamic evolution of coarse-grain mesomolecules was carried out in cells of 20 × 20 × 20 DPD unit length with periodic boundary conditions. The composition of the emulsion was chosen to be similar to a Mexican heavy crude oil: asphaltenes, 11.9%; resins, 11.8%; aromatics, 42.7%; saturates, 29.6%; polymer, 4%; and two water drops of 3 DPD length units in radius. Finally, a drastic change in the coalescence of water molecules is observed for a short co-polymer length with respect to long co-polymer lengths.
Secretory Phospholipase A <sub>2</sub> Is the Principal Bactericide for Staphylococci and Other Gram-Positive Bacteria in Human Tears (1998)

We examined human tears for molecules that killed gram-positive bacteria. The principal mediator of bactericidal activity against staphylococci proved to be a calcium-dependent enzyme, secretory phospholipase A2. Whereas the concentration of secretory phospholipase A2 in the normal tear film exceeded 30 microg/ml, only 1.1 ng (<0.1 nM) of the enzyme per ml sufficed to kill Listeria monocytogenes and 15 to 80 ng/ml killed Staphylococcus aureus. Despite its efficacy against gram-positive bacteria, secretory phospholipase A2 lacked bactericidal activity against gram-negative organisms (Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa) when tested in the ionic environment of tears. Given the presence of secretory phospholipase A2 in tears, intestinal secretions, and leukocytes, this enzyme may play a substantial role in innate mucosal and systemic bactericidal defenses against gram-positive bacteria.
Vertrouwen bij de brandweer : hoe vertrouwen vertrouwen beïnvloed en andersom (2009)

De brandweer Amsterdam Amstelland is geregionaliseerd in 2008.\nEen grote reorganisatie van zes brandweerkorpsen die ook nog een \nals een zelfstandig bedrijf verder moeten. Organisatieverandering is\nin dit geval noodzakelijk maar brengt vaak meer met zich mee \ndan alleen de voorzien verandering. Een van die dingen is teruggang \nvan vertrouwen. En juist vertrouwen is het noodzakelijke smeermiddel\n dat zorgt voor de mogelijkheid tot samenwerking tussen mensen.\nIn dit artikel beschrijf ik de rol van vertrouwen in de reorganisatie \nvan de brandweer Amsterdam Amstelland bezien vanuit het midden \nmanagement. De theorie schrijft voor dat verandering een negatieve \ninvloed heeft op het vertrouwen maar gekeken naar het gebrekkige \nvertrouwen in de bestaande brandweer organisatie lijkt het erop\n dat de het vertrouwen, of liever gezegd het gebrek eraan, meer\ninvloed heeft op verandering dan andersom.
Increased optical saturation intensities in GaInAs multiple quantum wells by the use of AlGaInAs barriers (1991)

Quaternary AlGaInAs is demonstrated to be an excellent barrier material for long-wavelength quantum well modulators. In addition to lower trap density than ternary AlInAs, the low valence-band discontinuity results in saturation intensities at least a factor of 30 higher than InGaAs wells with InP barriers. Decreasing barrier thicknesses increases saturation intensities by an additional factor of 5.
Expression of Interleukin‐17 in Ischemic Brain Tissue (2005)

Ischemic brain injury is acute local inflammation, leading to accumulation of pro-inflammatory cytokines. Cytokines influence the recruitment of leucocytes and play a key role in the inflammatory injury processes. Recently, a number of studies have demonstrated a close relationship between brain ischemia and cytokines. Interleukin-17 (IL-17) is a newly identified T-cell-specific cytokine. In this study, we evaluated the source and the action of IL-17 over the course of cerebral ischemia in rats (Sprague-Dawley) and humans. The levels of IL-17 in the ischemic hemisphere of the human brain, which was removed at necropsy, were assayed immunohistochemically. In rats, permanent middle cerebral artery occlusion (pMCAO) was obtained by inserting nylon monofilament into the right external carotid artery, occluding the right middle cerebral artery. The expression of IL-17 mRNA in rat was assayed using oligoprobe in situ hybridization. IL-17 production by neuroglial cells was assayed by double-staining using antibody glial fibrillary acidic protein (GFAP) and antibody IL-17. Levels of IL-17 were elevated in the ischemic hemispheres of human brain compared with the opposite normal hemispheres and peaked at days 3-5 after brain ischemia. The IL-17-positive cells were found in the ischemic lesion region. IL-17 mRNA was also elevated in ischemic hemispheres of pMCAO-operated rats, which were slightly elevated after 1 h and peaked at 6 days. IL-17 and GFAP double-stained were extensive in rat ischemic hemisphere. The ischemia-induced IL-17 expression in human brain reported here for the first time was very similar to that in rat model except that the peak was slightly earlier. We found for the first time that IL-17 was involved in an intense inflammatory reaction of brain ischemic injury in human. In pMCAO-operated rats, our findings suggest that IL-17 is produced by the neuroglial cells in the brain region undergoing ischemic insult. We suggest that in additional to T cells the neuroglial cell may be another cellular origin of IL-17 in later progression of brain ischemia.
Hybrid MOSFET/driver for ultra-fast switching (2009)

The ultra-fast switching of power MOSFETs, in about 1 ns, is very challenging. This is largely due to the parasitic inductance that is intrinsic to commercial packages used for both MOSFETs and drivers. Parasitic gate and source inductance not only limit the voltage rise time on the MOSFET internal gate structure but can also cause the gate voltage to oscillate. This paper describes a hybrid approach that substantially reduces the parasitic inductance between the driver and MOSFET gate, as well as between the MOSFET source and its external connection. A flip-chip assembly is used to directly attach a die-form power MOSFET and driver on a PCB. The parasitic inductances are significantly reduced by eliminating bond wires and minimizing lead length. The experimental results demonstrate ultra-fast switching of the power MOSFET with excellent control of the gate-source voltage.
POTREBA I ZNAČAJ RAZVOJA LOGISTIČKOG CENTRA U DOBOJU (2021)

Buduci da Republika Srpska i Bosna i Hercegovina žele da razvijaju izvozno orijentisanu privredu, neophodno je obezbijediti odgovarajucu podrsku u domenu logistike, prvenstveno kroz primjenu savremenih tehnologija transporta, skladistenja, pakovanja i pretovara robe. Logisticki centri predstavlјaju klјucne elemente te podrske i njihovim razvojem i izgradnjom doci ce do privlacenja međunarodnih robnih i transportnih tokova, stranog kapitala i multinacionalnih kompanija koje bi iz ovih centara pokrivale regionalno tržiste ne samo Bosne i Hercegovine, vec i susjednih zemalјa. Ovi centri se mogu predstaviti kao savremeni objekti u kojima se prikuplјa, cuva, dorađuje i priprema roba za dalјu distribuciju do kupaca. Oslanjajuci se na svjetska iskustva koja pokazuju da se logisticki centri isklјucivo osnivaju u okviru velikih transportnih cvorova, predlažemo da se u Doboju izgradi jedan savremeni logisticki centar. Sam geografsko-saobracajni položaj Doboja, koji se nalazi na raskrsnici svih važnijih transportnih koridora i pravaca u Bosni i Hercegovini, predstavlјa izuzetnu pogodnost u pogledu razvoja jednog ovakvog centra. Razvojem i izgradnjom logistickog centra u Doboju obezbijedice se podrska izvozno orijentisanoj privredi, proizvodnim i trgovackim sistemima, kao i smanjenje logistickih i ukupnih troskova reprodukcije. Takođe ce se omoguciti uklјucivanje Bosne i Hercegovine, Republike Srpske i sire regije Doboja u jedinstveni evropski transportni sistem i međunarodne robne tokove. Ovaj rad ima za cilј da predstavi koncept razvoja logistickog centra u Doboju, i da ukaže na njegov znacaj kako za siru regiju Doboja, tako i za Republiku Srpsku i Bosnu i Hercegovinu.
Toward a Conceptualization of Mentoring (1988)

Anderson and Shannon argue that effec tive mentoring programs must be grounded on a clear and strong concep tual foundation. Such a foundation in cludes a carefully articulated approach to mentoring which would include de lineation of: a definition of the mentor ing relationship, the essential functions of the mentor role, the activities through which selected mentoring functions will be expressed, and the dispositions that mentors must exhibit if they are to carry out requisite mentoring functions and activities.
A panorama-based technique for annotation overlay and its real-time implementation (2002)

The panorama-based annotation method described uses a panoramic image as the source of information about the positions of the annotations. It finds image alignment parameters between an input frame and the panoramic image and then maps the positions of annotations from the panoramic image to the input frame and displays the input frame overlaid with those annotations. Camera movement from place to place is made possible by preparing a set of panoramic images in advance. The panoramic image that gives the least mean squares error of the image alignment is selected automatically and is appropriately switched as the camera moves around. The position of the camera can be tracked by monitoring the switching of selected panoramic images. Experimental results show that this method can find image alignment parameters, display input frames overlaid with the annotations, and switch the panoramic image appropriately in real-time.
An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae. (1991)

We have developed a method to isolate mutants of Saccharomyces cerevisiae that are primarily defective in the transcription of 35S ribosomal RNA (rRNA) genes by RNA polymerase I. The method uses a system in which the 35S rRNA gene is fused to the GAL7 promoter and is transcribed by RNA polymerase II under control of the GAL regulatory system. Chromosomal mutations affecting components specifically involved in synthesis of 35S rRNA by RNA polymerase I can be suppressed by this hybrid gene in the presence of inducer (galactose) but not in its absence. We looked for mutants the growth of which depended on the presence of plasmid expressing the hybrid gene. For this purpose, we used a red/white-colony color assay as the initial screen followed by a test for galactose-dependent growth. We have thus isolated many mutants and identified at least nine genes (RRN1-RRN9) involved in 35S rRNA synthesis, two of which correspond to known RNA polymerase I subunit genes RPA190 and RPA135.
Nitrate Therapy for Stable Angina Pectoris (1998)

The organic nitrates are widely used in the management of coronary artery disease. They are given not only to patients with stable angina pectoris, but also to those with unstable angina, acute myocardial infarction, and heart failure. Although they are effective for the treatment of these disorders, their therapeutic value is compromised by the rapid development of tolerance during sustained therapy. This review will be limited to the use of organic nitrates in patients with chronic stable angina pectoris, but many of the principles enunciated are relevant to other clinical situations.In 1879 Murrell reported that a 1 percent solution . . .
Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia (2010)

In this study, we attempted to assess the interactions of resveratrol, a natural compound present in various plant species, with the purine analogues fludarabine and cladribine in terms of their effects on DNA damage and apoptosis in chronic lymphocytic leukemia (CLL) cells. The experiments were performed ex vivo using short-term cell cultures of blood and bone marrow cells from newly diagnosed untreated patients. We analyzed the expression of active caspase-3 and the BCL-2/BAX ratio as markers of apoptosis and the expression of phosphorylated histone H2AX (γH2AX) and activated ATM kinase, which are reporters of DNA damage. The results of our study revealed that resveratrol induced apoptosis in CLL cells in a tumor-specific manner but did not affect non-leukemic cells, and apoptosis was associated with a decreased BCL2/BAX ratio. Here, we report for the first time that both resveratrol + fludarabine and resveratrol + cladribine caused a higher rate of apoptosis in comparison to the rate caused by a single drug. The percentage of apoptotic cells induced by resveratrol alone was higher in the group of patients with better prognostic markers than in those with worse prognostic markers. However, the rates of apoptosis caused by resveratrol combined with purine analogues were independent of ZAP-70 and CD38 expression and the clinical state of the disease; they were only dependent on the presence of high-risk cytogenetic abnormalities. We also observed an increase in γH2AX expression together with a rise in activated ATM in most of the analyzed samples. The obtained results indicate that resveratrol might warrant further study as a new therapeutic option for CLL patients. This naturally occurring substance may be used as a single agent, especially in older persons for whom there are some limitations for the use of aggressive treatment. On the other hand, a lower purine analogue dose could potentially be used in combination with resveratrol because of their combined effect. One of the mechanisms of action of resveratrol is the induction of DNA damage, which ultimately leads to apoptosis.
Condensation of phosphonate anions with 4-amino-5-nitrosopyrimidines: a new pteridine synthesis (1971)

The condensation of diethyl phosphonate carbanions, prepared from α-bromo-esters, -nitriles, or -ketones, with 4,6-diamino-5-nitrosopyrimidines constitutes a versatile and unequivocal route to pteridin-7(8H)-ones, 7-aminopteridines, and 7-alkyl- or aryl-pteridines.
Moment and curvature preserving technique for accurate ellipse boundary detection (2002)

Circles and their elliptic projections are very commonly used image features in computer vision applications. Thus, it is very important to be able to determine their location in an accurate manner. A technique for determining an ellipse boundary with subpixel precision is proposed. The technique, called the moment and curvature preserving detection (MCP), utilizes the first three intensity moments and the intensity gradient of the image. The idea of using moments for subpixel edge detection is not new, but in the case of ellipses the moments do not provide sufficient information for precise detection. However, if the local curvature is augmented to the observations, the ellipse boundary can be determined reliably.
Freestanding ultrathin single-crystalline SiC substrate by MeV H ion-slicing (2018)

SiC is a widely used wide-bandgap semiconductor, and the freestanding ultrathin single-crystalline SiC substrate provides the material platform for advanced devices. Here, we demonstrate the fabrication of a freestanding ultrathin single-crystalline SiC substrate with a thickness of 22 μm by ion slicing using 1.6 MeV H ion implantation. The ion-slicing process performed in the MeV energy range was compared to the conventional case using low-energy H ion implantation in the keV energy range. The blistering behavior of the implanted SiC surface layer depends on both the implantation temperature and the annealing temperature. Due to the different straggling parameter for two implant energies, the distribution of implantation-induced damage is significantly different. The impact of implantation temperature on the high-energy and low-energy slicing was opposite, and the ion-slicing SiC in the MeV range initiates at a much higher temperature.
A New Human Gene Located in thePKD1Region of Chromosome 16 Is a Functional Homologue toERV1of Yeast (1995)

A new human gene has been identified on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1) by analysis of a genomic cosmid clone and cDNAs. The gene contains at least one intron and is actively transcribed in tissues from kidney and brain. The putative gene product is predicted to be homologous to the yeast scERV1 protein by virtue of the high degree of identity (42%) over the entire length of the polypeptides. In former studies the yeast scERV1 gene was found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell-division cycle. In this study a yeast expression vector with a chimeric reading frame coding for the first 21 amino acids of the yeast protein and the terminal 100 amino acid residues of the human factor was transformed into yeast mutants with two different defects for scERV1. The chimeric human gene product was able to complement the yeast mutants and restored near normal viability. This identifies the human gene as a structural and functional homologue of the scERV1 gene.
Multicenter phase II efficacy trial of toremifene in tamoxifen-refractory patients with advanced breast cancer. (1993)

We conclude that there is major cross-resistance between tamoxifen and toremifene and that only occasional tamoxifen-refractory patients will have objective responses to toremifene.
High-Performance Polymer Electret for Micro Seismic Generator (2005)

Development of micro seismic generator for energy harvesting applications is presented. In order to fabricate MEMS-friendly high-performance electret film, CYTOP is adopted as an electret material and the charge density and the charge stability of CYTOP is experimentally characterized. When corona charging is employed, charge density as large as 2.8 mC/m 2 is obtained for 3 μm-thick CYTOP film, which is 3 times larger than that of Teflon AF. It is found in thermally-stimulated discharge measurement that charge implanted in CYTOP is stable at least up to its glass transition temperature. In power generation experiments using a prototype seismic generator, maximum output power of 6.4 μW is obtained with 1 mm p-p oscillation at 20 Hz. It is also found that the trend of the experimental data is in good accordance with that of the theoretical prediction.
Synchronized Multi-trip Multi-traffic Pickup & Delivery in City Logistics (2016)

The paper introduces the first methodology addressing with a single fleet of vehicles the routing of the three different types of transportation demands encountered in City Logistics, inbound, outbound and intra-city traffic. We propose a tabu search meta-heuristic calling on various neighbourhoods, dynamically selected, to provide an efficient search combining exploration and exploitation capabilities. The result analysis of extensive computational experiments qualify the impact of a number of major problem characteristics and search strategies on the quality of the meta-heuristic, the behaviour of the solutions, and the management of the City Logistics system.
THE MEASUREMENT OF EXTRAVASCULAR LUNG WATER BY THERMAL‐GREEN DYE INDICATOR DILUTION* (1982)

The theory and practice of the thermal-dye indicator-dilution method for measurement of EVLW has been discussed, and all available animal data from our laboratory correlating EVTV and gravimetric EVLW have been presented. The method appears to function well over the entire range of edema seen , and to be minimally dependent on cardiac output. Thermal-indicator loss does not seem to be a significant problem and does not impair the accuracy of this method. Out results are consistent with earlier works in the field in identifying significant differences between the isotopic EVLW methods and the thermal-dye method, and it seems likely that these differences are due to the much greater diffusion rate of the thermal indicator.
MD-12: BRANCHING OUT. (1992)

8 ASUBTITLE: THE RELEASE OF DESIGN DETAILS OF MCDONNELL DOUGLAS' AMBITIOUS MD-12 DOUBLE-DECK WIDEBODY HAS CONFIRMED THE COMPANY'S EXPECTED DEPARTURE FROM ITS TRIJET HERITAGE.
On-farm euthanasia of broiler chickens: effects of different gas mixtures on behavior and brain activity (2004)

The purpose of this study was to investigate the suitability of gas mixtures for euthanasia of groups of broilers in their housing by increasing the percentage of CO2. The suitability was assessed by the level of discomfort before loss of consciousness, and the killing rate. The gas mixtures injected into the housing were 1) 100% CO2, 2) 50% N2 + 50% CO2, and 3) 30% O2 + 40% CO2 + 30% N2, followed by 100% CO2. At 2 and 6 wk of age, groups of 20 broiler chickens per trial were exposed to increasing CO2 percentages due to the injection of these gas mixtures. Behavior and killing rate were examined. At the same time, 2 broilers per trial equipped with brain electrodes were observed for behavior and brain activity. Ten percent of the 2-wk-old broilers survived the increasing CO2 percentage due to the injection of 30% O2 + 40% CO2 + 30% N2 mixture, therefore this mixture was excluded for further testing at 6 wk of age. At 6 wk of age, 30% of the broilers survived in the 50% N2 + 50% CO2 group. The highest level of CO2 in the breathing air (42%) was reached by the injection of the 100% CO2 mixture, vs. 25% for the other 2 mixtures. In all 3 gas mixtures, head shaking, gasping, and convulsions were observed before loss of posture. Loss of posture and suppression of electrical activity of the brain (n = 7) occurred almost simultaneously. The results of this experiment indicate that euthanasia of groups of 2- and 6-wk-old broilers by gradually increasing the percentage of CO2 in the breathing air up to 40% is possible.
La pràctica educativa al Parvulari (2011)

infant el trobar en l'escola.D'aquesta manera, tenint en compte la base abans descrita, algunes