gebhart/patrepeval huggingface dataset:
Knee pain caused by a fiducial marker in the medial femoral condyle: A clinical and anatomic study of 20 cases (2001)

After 2-pin-based ROBODOC hip arthroplasty procedures, 10 of 18 patients reported persistent severe pain at the site of pin implantation in the medial femoral condyle. In a cadaver study, we found that the infrapatellar branch of the saphenous nerve, the saphenous nerve and the anterior cutaneous branches of the femoral nerve had been injured by the pins. At least one of these nerves was injured in 11 of the 20 specimens examined. Our findings indicate that the knee-pain may be partly caused by injuries to these nerves.
Mn-doped Ba0.6Sr0.4TiO3 high-K gate dielectrics for low voltage organic transistor on polymer substrate (2005)

In this letter, we report on the role of Mn doping in markedly reducing leakage currents in Ba0.6Sr0.4TiO3 (BST) high-K gate dielectrics utilized in organic thin film transistors (OTFTs) fabricated on plastic substrates. Undoped and 3% Mn-doped BST thin films, deposited by rf magnetron sputtering at room temperature on Pt∕Ti∕SiO2∕Si substrates, exhibited relative dielectric constants of ∼24–28. At an applied electric field of 250kV∕cm, the 3% Mn-doped BST films exhibited leakage current densities below 2×10−8A∕cm2 compared to the much higher value of 5×10−4A∕cm2 characteristic of undoped BST films. Pentacene based OTFTs using 3% Mn-doped BST gate dielectrics exhibited low voltage operation of &lt;10V. This demonstrates the potential use of Mn-doped BST films as high-K gate dielectrics for stable and low operating voltage OTFTs.
Antibacterial Effects of Butylated Hydroxyanisole (BHA) against <i>Bacillus</i> species (1982)

ABSTRACT The antibacterial effect of butylated hydroxyanisole (BHA) was evaluated in laboratory media and in two foods. In nutrient broth growth of Bucillus species (three strains of B. cereus , two of which were enterotoxigenic, and one strain each of B. subtilis and B. megaterium ) was inhibited by 75 ppm of BHA. In tests with food systems growth inhibition of vegetative cells of these organisms required 1000 ppm in cooked rice and 5000 ppm in strained chicken. The effect of BHA was bacteriostatic at the tested levels (≤ 200 ppm in laboratory media and ≤ 10,000 ppm in the food systems), and viable cells were recovered from all samples. Bacterial growth resumed in samples which contained bacteriostatic levels of BHA after dilution with antioxidant free broth or food.
Inexpensive Near-IR Sun Photometer for Measuring Total Column Water Vapor (2007)

Abstract An inexpensive two-channel near-IR sun photometer for measuring total atmospheric column water vapor (precipitable water) has been developed for use by the Global Learning and Observations to Benefit the Environment (GLOBE) environmental science and education program and other nonspecialists. This instrument detects sunlight in the 940-nm water vapor absorption band with a filtered photodiode and at 825 nm with a near-IR light-emitting diode (LED). The ratio of outputs of these two detectors is related to total column water vapor in the atmosphere. Reference instruments can be calibrated against column atmospheric water vapor data derived from delays in radio signals received at global positioning satellite (GPS) receiver sites and other independent sources. For additional instruments that are optically and physically identical to reference instruments, a single-parameter calibration can be determined by making simultaneous measurements with a reference instrument and forcing the derived precipitable water values to agree. Although the concept of near-IR detection of precipitable water is not new, this paper describes a first attempt at developing a protocol for calibrating large numbers of inexpensive instruments suitable for use by teachers, students, and other nonspecialists.
Power factor and temperature coefficient of solid (amorphous) dielectrics (1946)

The first page of this article is displayed as the abstract.
Clinical safety and efficacy studies of a novel formulation combining 1.2% clindamycin phosphate and 0.025% tretinoin for the treatment of acne vulgaris. (2007)

Clindamycin phosphate 1.2% and tretinoin 0.025% gel (CLIN/RA gel [ZIANA Gel]) is a novel topical combination agent approved by the FDA for the treatment of acne vulgaris in patients 12 years of age or older. A solution of clindamycin phosphate 1.2% combined with partially solubilized and crystalline tretinoin 0.025% suspended in an aqueous-based, alcohol-free gel formulation, CLIN/RA gel was studied in 2 randomized, vehicle-controlled trials involving more than 4,500 patients. Efficacy results from these studies showed that treatment with the combination significantly reduced lesion counts and improved patients' overall appearance to a greater extent than the individual components. Individual ingredients and the combination were well-tolerated. Among those treated with the combination formulation, discontinuation rates due to adverse events were 1% or less.
Local features are not lonely &#x2013; Laplacian sparse coding for image classification (2010)

Sparse coding which encodes the original signal in a sparse signal space, has shown its state-of-the-art performance in the visual codebook generation and feature quantization process of BoW based image representation. However, in the feature quantization process of sparse coding, some similar local features may be quantized into different visual words of the codebook due to the sensitiveness of quantization. In this paper, to alleviate the impact of this problem, we propose a Laplacian sparse coding method, which will exploit the dependence among the local features. Specifically, we propose to use histogram intersection based kNN method to construct a Laplacian matrix, which can well characterize the similarity of local features. In addition, we incorporate this Laplacian matrix into the objective function of sparse coding to preserve the consistence in sparse representation of similar local features. Comprehensive experimental results show that our method achieves or outperforms existing state-of-the-art results, and exhibits excellent performance on Scene 15 data set.
Antiallergic Activity of Ginseng and its Ginsenosides (2003)

In this study, we measured the antiallergic activities of ginsenosides isolated from the root of Panax ginseng ( Araliaceae), and of their metabolites, as produced by human intestinal bacteria. Compound K, which was identified as a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and on the PCA reaction. The inhibitory activity of compound K was more potent than that of disodium cromoglycate, one of the commercial anti-allergic drugs. This compound demonstrated a membrane stabilizing action on differential scanning calorimetry. However, compound K did not inhibit the activation of hyaluronidase and did not scavenge active oxygen. These results suggest that the antiallergic action of compound K originates from its cell membrane stabilizing activity and that the ginsenosides of ginseng are prodrugs with extensive antiallergic properties. Abbreviations. compound K:20- O-beta- D-glucopyranosyl-20( S)-protopanaxadiol DNP:dinitrophenol DSCG:disodium cromoglycate DPPC:dipalmitoylphosphatidylcholine DPPH:1,1-diphenyl-2-picrylhydrazyl HSA:human serum albumin IC 50 :50% inhibitory concentration EC 50 :50% effective concentration XOD:xanthine oxidase ICR:Institute of Cancer Research PBS:phosphate buffered saline PCA:passive cutaneous anaphylaxis RAW264.7:mouse monocyte leukemiaRBL-2H3: rat basophil leukemia SD:Sprague-Dawley
A synthetic test circuit for current switching tests of HVDC circuit breakers (2008)

High voltage direct current (HVDC) circuit breaker current switching test in a test laboratory is difficult due to the limited test power installation. Reproduction of test stresses by means of direct testing confronts huge investment. Synthetic testing, as an alternative method, could amplify the test power more than ten times with a relative low cost. A synthetic test circuit based on the most used parallel current injection method was developed for the current switching test of HVDC circuit breakers. This synthetic test circuit could reproduce the current and voltage stresses equal to or greater than those could meet in service.
Thérapie génique appliquée à la protoporphyrie érythropoïétique humaine : Correction d'un épissage alternatif anormal par l'utilisation d'oligonucléotides en antisens (2012)

L'accumulation pathologique de protoporphyrines IX (PPIX) dans les cellules erythroides peut etre due a un deficit partiel d'activite de la ferrochelatase (FECH) ou d'une suractivite de l'ALAS2. 96% des patients protoporphyriques (PPE) presentent en trans d'une mutation du gene FECH un allele hypormorphe IVS3 -48C favorisant un epissage alternatif anormal. L'ARNm anormal est degrade et contribue a la diminution de l'activite FECH responsable de l'expression phenotypique. Nous avons identifie un oligonucleotide en antisens (V1-ASO) capable de rediriger l'epissage du site cryptique anormal vers le site physiologique. Cette redirection par V1-ASO permet de reduire de 60 % l'accumulation de PPIX dans des cultures de progeniteurs erythroides PPE.
The maternal gene <i>nanos</i> has a central role in posterior pattern formation of the <i>Drosophila</i> embryo (1991)

A group of maternal genes, the posterior group, is required for the development of the abdominal region in the Drosophila embryo. We have used genetic as well as cytoplasmic transfer experiments to order seven of the posterior group genes (nanos, pumilio, oskar, valois, vasa, staufen and tudor) into a functional pathway. An activity present in the posterior pole plasm of wild-type embryos can restore normal abdominal development in posterior group mutants. This activity is synthesized during oogenesis and the gene nanos most likely encodes this activity. The other posterior group genes have distinct accessory functions: pumilio acts downstream of nanos and is required for the distribution or stability of the nanos-dependent activity in the embryo. Staufen, oskar, vasa, valois and tudor act upstream of nanos. Embryos from females mutant for these genes lack the specialized posterior pole plasm and consequently fail to form germ-cell precursors. We suggest that the products of these genes provide the physical structure necessary for the localization of nanos-dependent activity and of germ line determinants.
Human Fall Detection Based on Motion Tracking and Shape Aspect Ratio (2016)

Automatic human fall detection based on video monitoring plays an important role in protecting vulnerable people especially the seniors whose falls could cause severe injuries and need attentions from others immediately. In this paper, an automatic human fall detection method based on human motion tracking and shape aspect ratio in real-time video is proposed. While most existing methods detect falls in homes, the proposed method is suitable for both outdoor and indoor environments. The method first detects human objects in general environment, then tracks their motions, meanwhile calculating and recording the motion characteristics of each person. Comparing with the existing fall detection method using shape aspect ratio, the proposed method has advantages of employing the shape aspect ratio together with the moving speed and direction to better detect human falls, as well as being able to detect falls toward different directions. Experiment results demonstrate that the proposed method can effectively detect human falls in general environments including outdoor places.
Flow cytometry in cancer stem cell analysis and separation (2012)

In recent years, a special type of cancer cell--the cancer stem cell (CSC)--has been identified and characterized for different tumors. CSCs may be responsible for the recurrence of a tumor following a primarily successful therapy and are thought to bear a high metastatic potential. For the development of efficient treatment strategies, the establishment of reliable methods for the identification and effective isolation of CSCs is imperative. Similar to their stem cell counterparts in bone marrow or small intestine, different cluster of differentiation surface antigens have been characterized, thus enabling researchers to identify them within the tumor bulk and to determine their degree of differentiation. In addition, functional properties characteristic of stem cells can be measured. Side population analysis is based on the stem cell-specific activity of certain ATP-binding cassette transporter proteins, which are able to transport fluorescent dyes out of the cells. Furthermore, the stem cell-specific presence of aldehyde dehydrogenase isoform 1 can be used for CSC labeling. However, the flow cytometric analysis of these CSC functional features requires specific technical adjustments. This review focuses on the principles and strategies of the flow cytometric analysis of CSCs and provides an overview of current protocols as well as technical requirements and pitfalls. A special focus is set on side population analysis and analysis of ALDH activity. Flow cytometry-based sorting principles and future flow cytometric applications for CSC analysis are also discussed.
A review of recent advances in thermophotovoltaics (1996)

Thermophotovoltaic (TPV) generation of electricity is attracting attention because of advances in materials and devices and because of a widening appreciation of the large number of applications that may be addressed using TPV-based generators. The attractions include the wide range of fuel sources and the potentially high power density outputs. The two main approaches to TPV generators are: (1) broad-band radiators, coupled with converters with bandgaps in the range 0.4-0.7 eV; and (2) narrow-band emitters coupled with lower-cost silicon converters. The key issues in realizing a viable TPV system are the durability, efficiency and properties of the radiant emitter; the recuperation of sub-bandgap photons; the optimization of the converter performance; and the recuperation of waste heat.
Microfluidic step-emulsification in axisymmetric geometry (2017)

Biphasic step-emulsification (Z. Li et al., Lab Chip, 2015, 15, 1023) is a promising microfluidic technique for high-throughput production of μm and sub-μm highly monodisperse droplets. The step-emulsifier consists of a shallow (Hele-Shaw) microchannel operating with two co-flowing immiscible liquids and an abrupt expansion (i.e., step) to a deep and wide reservoir. Under certain conditions the confined stream of the disperse phase, engulfed by the co-flowing continuous phase, breaks into small highly monodisperse droplets at the step. Theoretical investigation of the corresponding hydrodynamics is complicated due to the complex geometry of the planar device, calling for numerical approaches. However, direct numerical simulations of the three dimensional surface-tension-dominated biphasic flows in confined geometries are computationally expensive. In the present paper we study a model problem of axisymmetric step-emulsification. This setup consists of a stable core-annular biphasic flow in a cylindrical capillary tube connected co-axially to a reservoir tube of a larger diameter through a sudden expansion mimicking the edge of the planar step-emulsifier. We demonstrate that the axisymmetric setup exhibits similar regimes of droplet generation to the planar device. A detailed parametric study of the underlying hydrodynamics is feasible via inexpensive (two dimensional) simulations owing to the axial symmetry. The phase diagram quantifying the different regimes of droplet generation in terms of governing dimensionless parameters is presented. We show that in qualitative agreement with experiments in planar devices, the size of the droplets generated in the step-emulsification regime is independent of the capillary number and almost insensitive to the viscosity ratio. These findings confirm that the step-emulsification regime is solely controlled by surface tension. The numerical predictions are in excellent agreement with in-house experiments with the axisymmetric step-emulsifier.
Dynamics of Poly(<scp>l</scp>-lysine) in Hyaluronic Acid/Poly(<scp>l</scp>-lysine) Multilayer Films Studied by Fluorescence Recovery after Pattern Photobleaching (2008)

Poly( L-lysine) (PLL)/hyaluronic acid (HA) multilayers are films whose thickness increases exponentially with the number of deposition steps. Such a growth process was attributed to the diffusion, in and out of the whole film, of at least one of the polyelectrolytes constituting the film. In the case of PLL/HA, PLL is known to be the diffusing species. In order to better understand the growth mechanism of such films, it is of primary importance to well characterize the diffusion process of the polyelectrolytes in the multilayer. This process is studied here by fluorescence recovery after pattern photobleaching. We show that the diffusion behavior is different when we consider either PLL chains that are deposited on top of the film or PLL chains embedded in the film, even below only one HA layer. For chains that are embedded, we find two populations: a mobile one with a diffusion coefficient, D, of the order of 0.1 microm(2) x s(-1) and a population that appears immobile ( D < 0.001 microm(2) x s(-1)). For chains deposited on top of the multilayer, a third population appears which is rapidly diffusing ( D congruent with 1 microm(2) x s(-1)). These results confirm the validity of the model generally accepted for the exponential growth process and in particular the existence of up to three subgroups of PLL chains from the point of view of their diffusion coefficient.
The Arab Spring and the U.S. Response:American and Middle Eastern Students Speak Out (2013)

The “Arab Spring” galvanized global media attention on political upheaval in the countries of the Middle East and North Africa (MENA). Observers around the world felt the rising tension and tumult of change, especially among the young people of the region, and yet the gulf between cultures continues to threaten understanding and peace. In an era when social networking rivals TV news coverage and when mobile text messages substitute for interpersonal channels of communication, the views held by U.S. and Middle Eastern college students can either unite or divide the cultures. In order to understand how young people view media and current events that frame the conflict, this study uses survey data as a comparative indicator of the level of conflict between students of MENA and the United States. This study examines communication activities and political views on college campuses in Doha, Qatar, Dubai, and Cairo, Egypt, and in Peoria, Illinois and Lafayette, Louisiana. The results show a higher level of engagement in news and public affairs among Middle Eastern students and a contrast in opinion regarding political issues and events.
<i>In Vivo</i> Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates (2016)

Unnatural sugar-mediated metabolic labeling of cancer cells, coupled with efficient Click chemistry, has shown great potential for in vivo imaging and cancer targeting. Thus far, chemical labeling of cancer cells has been limited to the small-sized azido groups, with the large-sized and highly hydrophobic dibenzocyclooctyne (DBCO) being correspondingly used as the targeting ligand. However, surface modification of nanomedicines with DBCO groups often suffers from low ligand density, difficult functionalization, and impaired physiochemical properties. Here we report the development of DBCO-bearing unnatural sugars that could directly label LS174T colon cancer cells with DBCO groups and subsequently mediate cancer-targeted delivery of azido-modified silica nanoconjugates with easy functionalization and high azido density in vitro and in vivo. This study, for the first time, demonstrates the feasibility of metabolic labeling of cancer cells with large-sized DBCO groups for subsequent, efficient targeting of azido-modified nanomedicines.
Mobile Edge Computing Empowers Internet of Things (2017)

In this paper, we propose a Mobile Edge Internet of Things (MEIoT) architecture by leveraging the fiber-wireless access technology, the cloudlet concept, and the software defined networking framework. The MEIoT architecture brings computing and storage resources close to Internet of Things (IoT) devices in order to speed up IoT data sharing and analytics. Specifically, the IoT devices (belonging to the same user) are associated to a specific proxy Virtual Machine (VM) in the nearby cloudlet. The proxy VM stores and analyzes the IoT data (generated by its IoT devices) in real-time. Moreover, we introduce the semantic and social IoT technology in the context of MEIoT to solve the interoperability and inefficient access control problem in the IoT system. In addition, we propose two dynamic proxy VM migration methods to minimize the end-to-end delay between proxy VMs and their IoT devices and to minimize the total on-grid energy consumption of the cloudlets, respectively. Performance of the proposed methods is validated via extensive simulations.
Clique partitions, graph compression and speeding-up algorithms (1991)

Article Clique partitions, graph compression and speeding-up algorithms Share on Authors: Tomás Feder Bellcore, Morristown, NJ Bellcore, Morristown, NJView Profile , Rajeev Motwani Stanford Univ., Stanford, CA Stanford Univ., Stanford, CAView Profile Authors Info & Claims STOC '91: Proceedings of the twenty-third annual ACM symposium on Theory of ComputingJanuary 1991 Pages 123–133https://doi.org/10.1145/103418.103424Online:03 January 1991Publication History 52citation1,288DownloadsMetricsTotal Citations52Total Downloads1,288Last 12 Months15Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Quantitative Methods for the Gas Chromatographic Characterization of Acidic Fermentation By-Products of Anaerobic Bacteria (1978)

The present report describes improved chromatographic procedures which are capable of separating and quantitating complex mixtures of acidic fermentation by-products produced by anaerobic bacteria grown in two glucose-containing media. These methods are reliable and are sensitive, being able to detect as low as 0.5 mumoles of each by-product. Sample preparation has been simplified, and the methylation conditions have been optimized. It is also indicated in this investigation that each culture produced different patterns of by-products in each medium, indicating that the types and quantities of by-products produced in one medium cannot be used as a basis for characterization of these same cultures when grown in a different medium. Finally, it is shown that cultures can be characterized by the distinctive molar proportions of by-products they produce within each medium.
Ultrasonic Wave Propagation and Anisotropy in Austenitic Stainless Steel Weld Metal (1980)

The propagation of ultrasonic waves in stainless steel weld metal, an anisotropic medium, is examined. Significant variations in ultrasonic velocity as well as in attenuation have been observed for dif- ferent propagation directions. Elastic-constant data have also been ac- quired from single crystals of stainless steel and used in a simple model to describe the weld metal. From this model, velocities of sound as well as beam deviations can be predicted. The effect of anisotropy on flaw detection in stainless steel welds is discussed and examples are given. The current work is compared with recent literature on this subject.