gebhart/patrepeval huggingface dataset:
Customer expectations versus perceptions of service performance in the foodservice industry (1998)

This study examines qualitative and quantitative differences between service expectations and perceived performance in the foodservice industry, using the profile accumulation technique. Parallel series of data were obtained for service performance perceptions from actual customers at two pizza restaurants. The three sets of data were compared qualitatively and quantitatively. Results showed that customers structured their perceptions of the service into a common set of elements (termed aspects) and attached quality attributes to each of these elements. The three data series exhibited very similar dimensionalities in terms of both aspects and attributes of the service. Attributes were identified as satisfiers or dissatisfiers. In order to gain insight about their structure they were separately recoded using four different authors’ lists of quality dimensions. The significance of their quantitative differences for positive and negative disconfirmation was also examined. Aspects and attributes were used to calculate matrices of quality metrics referring to both the “aspects” dimensions provided by respondents and the dimension lists of the four authors. The work demonstrates that it is possible to obtain and analyse customers’ expectations and perceptions without making pre‐assumptions about them, and will therefore be of interest to managers and marketers of restaurants and other services.
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents (2013)

Microtubule-stabilizing agents (MSAs) are efficacious chemotherapeutic drugs widely used for the treatment of cancer. Despite the importance of MSAs for medical applications and basic research, their molecular mechanisms of action on tubulin and microtubules remain elusive. We determined high-resolution crystal structures of αβ-tubulin in complex with two unrelated MSAs, zampanolide and epothilone A. Both compounds were bound to the taxane pocket of β-tubulin and used their respective side chains to induce structuring of the M-loop into a short helix. Because the M-loop establishes lateral tubulin contacts in microtubules, these findings explain how taxane-site MSAs promote microtubule assembly and stability. Further, our results offer fundamental structural insights into the control mechanisms of microtubule dynamics.
Neuropeptide cycloprolylglycine increases the levels of brain-derived neurotrophic factor in neuronal cells (2016)

It was shown for the first time that the endogenous cyclic dipeptide cycloprolylglycine (CPG) at concentrations of 10(-7) and 10(-3) M and piracetam at a concentration of 10(-3) M increased the content of brainderived neurotrophic factor (BDNF) in the culture of neuronal cells in normal state and under conditions of glutamate and 6-oxydopamine neurotoxicity. This may indicate the possible involvement of BDNF in the mechanism of action of neuropeptide CPG and piracetam.
Optimization of pseudomorphic HEMT's supported by numerical simulations (1997)

Measurements and simulations of three different pseudomorphic high electron mobility transistors (PHEMT's) are presented. The PHEMT's possess the same epitaxial structure but different geometrical properties. For the simulations, the generic device simulator MINIMOS-NT is employed. This simulator is not restricted to planar device surfaces but is able to model complex surface topologies including the effect of passivating dielectric layers. Mixed hydrodynamic and drift-diffusion simulations are demonstrated. They include the DC characteristics as well as the bias-dependent gate capacitances. Thus, bias-dependent current-gain cutoff frequencies f/sub T/ can be calculated. The results compare very well with the values obtained by small-signal parameter extractions from S-parameter measurements. Although a single consistent set of parameters is used for the simulations of all three devices, their characteristics are reproduced with an accuracy to our knowledge not reported before. Therefore, the DC and RF properties of PHEMT's with geometries significantly different from the measured devices can be reliably predicted.
Thermoelectric figure of merit of quantum wire superlattices (1995)

The electrical conductivity, the thermoelectric power, and the electrical contribution to the thermal conductivity of quantum wire superlattices have been studied. The effects of tunneling through the barriers due to finite potential off-sets and of the thermal currents through the barrier layers are shown to be essential to describe properly the thermoelectric figure of merit of realistic quantum wire superlattices. The figure of merit exhibits a maximum as a function of superlattice period which, for large barrier off-sets, is found to be substantially enhanced over that for the bulk material and also larger than that for quantum well superlattices.
Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo (2003)

Antigen-specific B cells are key players in many autoimmune diseases through the production of autoreactive antibodies that can cause severe tissue damage and malfunction. We have designed and expressed a fusion protein, referred to as MOG-Fc, composed of the extracellular Ig-like domain of human myelin oligodendrocyte glycoprotein (MOG) and the C(H)2 and C(H)3 domains of the human IgG1 heavy chain. The dimerized fusion protein was capable of mediating cytotoxicity against a MOG-reactive hybridoma line in vitro. Likewise, MOG-Fc significantly reduced the number of circulating MOG-reactive B cells in an anti-MOG Ig heavy chain knock-in mouse model. Our study shows that autoantigen-reactive B lymphocytes can be efficiently and selectively eliminated by an autoantigen Fcgamma1 fusion protein in vitro as well as in vivo. Such fusion proteins may provide a platform for the development of highly selective therapeutic approaches.
The use of solid sorbents for direct accumulation of organic compounds from water matrices–a review of solid‐phase extraction techniques (1989)

Abstract The main principles of solid‐phase extraction techniques are reviewed in this paper. Various solid sorbents can be used as a suitable trap for direct accumulation of organic compounds from aqueous solutions. The trapped analytes can be desorbed by elution with suitably chosen liquid phases. These preconcentration procedures can be considered as low performance liquid chromatography and the efficiency of the procedure can thus be related to the retention characteristics of the preconcentration column. The main sorbents used for trace enrichment purposes are also reviewed. Besides, the concise methodology, sample storage, and automation are discussed. The advantages of solid phase extraction as compared to liquid‐liquid extraction are given as well as some drawbacks of this method.
Phosphorylation of <i>smg</i> p21B/<i>rap</i>1B p21 by cyclic GMP‐dependent protein kinase (1992)

smg p21B/rap1B p21, a member of ras p21-like small GTP-binding protein superfamily, has been shown to be phosphorylated by cyclic AMP-dependent protein kinase (protein kinase A). We show here that this protein was also phosphorylated by cyclic GMP-dependent protein kinase (protein kinase G) in a cell-free system. The same serine residue (Ser179) in the C-terminal region was phosphorylated by both protein kinases G and A. The Km and Vmax values of smg p21B for protein kinase G were 5 x 10(-7) M and 4 x 10(-9) mol/min/mg, and those values for protein kinase A were 1 x 10(-7) M and 3 x 10(-8) mol/min/mg.
Interaction of Dietary Fatty Acids with Tumour Necrosis Factor Family Cytokines during Colon Inflammation and Cancer (2014)

Intestinal homeostasis is precisely regulated by a number of endogenous regulatory molecules but significantly influenced by dietary compounds. Malfunction of this system may result in chronic inflammation and cancer. Dietary essential n-3 polyunsaturated fatty acids (PUFAs) and short-chain fatty acid butyrate produced from fibre display anti-inflammatory and anticancer activities. Both compounds were shown to modulate the production and activities of TNF family cytokines. Cytokines from the TNF family (TNF- α, TRAIL, and FasL) have potent inflammatory activities and can also regulate apoptosis, which plays an important role in cancer development. The results of our own research showed enhancement of apoptosis in colon cancer cells by a combination of either docosahexaenoic acid (DHA) or butyrate with TNF family cytokines, especially by promotion of the mitochondrial apoptotic pathway and modulation of NF κ B activity. This review is focused mainly on the interaction of dietary PUFAs and butyrate with these cytokines during colon inflammation and cancer development. We summarised recent knowledge about the cellular and molecular mechanisms involved in such effects and outcomes for intestinal cell behaviour and pathologies. Finally, the possible application for the prevention and therapy of colon inflammation and cancer is also outlined.
Genetic and Epigenetic Alterations of Lysophosphatidic Acid Receptor Genes in Rodent Tumors by Experimental Models (2011)

Lysophosphatidic acid (LPA) is a bioactive mediator and induces several biological effects, including cell proliferation, migration, morphogenesis and differentiation. LPA interacts with at least six G protein-coupled receptors (GPCRs), including LPA receptor-1 (LPA(1)), LPA(2), LPA(3), LPA(4), LPA(5) and LPA(6). These receptors show different biological functions through the binding of LPA, depending on the type of cells. In human malignancies, a high level of LPA production was found in plasma and ascites in ovarian cancer cases. Moreover, aberrant expression levels of LPA receptor genes were detected in some cancer cells. Therefore, it is suggested that LPA receptors may be involved in the pathogenesis of tumor cells as well as LPA per se. Recently, we have reported that alterations of LPA receptor genes also occur in rodent tumors. In this review, we summarize the recent evidence in the investigations of LPA receptor alterations in rodent tumors by experimental models.
Photoassisted Anodic Etching of Gallium Nitride (1997)

The first study of photo‐assisted anodic etching of unintentionally doped n‐GaN at room temperature is reported here. The electrolyte used is a mixture of buffered aqueous solution of tartaric acid and ethylene glycol. The etching rate varies from ∼20 Å/min to as high as 1600 Å/min. A systematic study shows that (i) the etch rate, as well as the surface roughness, increases with the current density; (ii) the etching rate is the highest when the pH of the electrolyte is ∼7; and (iii) the etching is faster when there is more ethylene glycol in the electrolyte solution.
REVIEWS (1930)

Journal Article REVIEWS Get access The Life and Letters of George Darley. By CLAUDE COLLEER ABBOTT. Humphrey Milford, Oxford University Press. 1928. Pp. xv + 285. 16s. net. KATHLEEN CAMPBELL KATHLEEN CAMPBELL Search for other works by this author on: Oxford Academic Google Scholar The Review of English Studies, Volume os-VI, Issue 21, January 1930, Pages 113–115, https://doi.org/10.1093/res/os-VI.21.113 Published: 01 January 1930
Composite Energy Storage Flywheel Design for Fatigue Crack Resistance (2009)

Composite flywheels can be a high-density energy storage device because of the very high specific strength and strength per unit weight. The rotors are fiber reinforced in the circumferential direction to resist centripetal loads resulting from high-speed rotation. A press-fit process is also used to induce precompression in the radial direction that improves mechanical strength by preventing radial separation of rotors. However, this design and fabrication process leaves the radial and axial directions of rotor vulnerable to propagation of fatigue crack growth in the rotor. A semiempirical approach is proposed to enhance the ldquocrack growthrdquo resistance of the rotor. Axial glass plies are incorporated to confine the crack growth through the radius and along the circumferential direction of rotor. The fracture properties of specific hybrid laminates are then measured to provide information required for an optimal rotor design.
Optimized three-component dye mixtures for achromatic guest-host liquid-crystal displays (1982)

We apply the matrix representation technique to determine the concentrations of three dye components in the liquid-crystal mixture needed to make a black-and-white guest-host display. This method employs the Newton-Raphson iterative process to match the tristimulus values of the mixture to the tristimulus values of the achromatic color. The color matches are thus metameric rather than spectral and hence depend upon the illuminant type. We give examples which show that practically any yellow, red, and blue dye components can be mixed to obtain a neutral color for a given illuminant, but that such mixtures generally have some coloration when viewed under other illuminant types. By extending the matrix representation technique into six dimensions, we show that it is possible to select optimum dye components according to the width and centroid wavelength of their absorption curves. These optimized components minimize the sensitivity of the neutral color to changes in illuminant type. We demonstrate that displays can be made with three optimized dye components which are achromatic under the extremes of both daylight and incandescent illumination. The absorption bands of these optimized dye components must be about 100 nm wide or wider, and the centroids of their respective absorption curves must be located within the ranges 445±10, 540±10, and 650±10 nm. We find that Heilmeier- and White-and-Taylor-type displays generally require different dye formulations. Examples are given for both display types.
Extraction of critical areas for opens in large VLSI circuits (2002)

This paper describes a new algorithm for the extraction of the critical area for opens. The presented algorithm allows for the analysis of large ICs and non-Manhattan geometry. Concept of the contact/via contacting regions is proposed and its relevance is discussed. Illustrative examples of the proposed algorithm are presented.
Identification of the human pim-1 gene product as a 33-kilodalton cytoplasmic protein with tyrosine kinase activity. (1988)

The human pim-1 gene was recently identified as a new putative oncogene located on chromosome 6p21, a region showing karyotypic abnormalities in particular leukemias. In the present work we characterized the pim protein product. In vitro translation of positively selected poly(A)+ mRNA indicates that this gene encodes a 33-kilodalton protein. Anti-pim antibodies were raised against a fused TrpE-pim protein induced in a bacterial expression vector. This antibody immunoprecipitated a 33-kilodalton protein from in vivo [35S]methionine-labeled K562 and KCl myelogenous origin cell lines. This protein was localized to the cytoplasm, and in vivo labeling as well as in vitro kinase assay suggests that it is a phosphoprotein with tyrosine kinase activity. This was further confirmed by performing autophosphorylation directly on a p33pim-containing gel band cut out after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The results imply that the tyrosine kinase activity of pim can be recovered after boiling the pim-1 protein in sample buffer: a feature not described yet for this class of protein. These results suggest that pim-1 is a new member of the subgroup of oncogenes encoding tyrosine kinases.
Data management of sensor signals for high bandwidth data streaming to the cloud (2016)

Internet of Things (IoT) and Cloud computing highlight new requirements for data collection, storage and analysis of user data. In this work we focus on the data collection from Bluetooth Low Energy (BLE) devices in order to identify and track data from things in real time, as well as to enhance data analysis by allowing processing in the Cloud. The paper proposes an IoT service architecture and a system implementation for a gateway service running on smart devices (tablets, smartphones) that supports generic access to BLE compliant sensors and allows on-the-fly sensor registration using an easy to use data information schema. The gateway is designed to support the processing (e.g. filtering) of sensor data before they are transferred to the cloud in example of FOG computing (that defines high bandwidth and low latency IoT distributed system). The experimental results demonstrate that the system supports real time communication and fast data collection, as the total time for data transmission (from smart sensors to the cloud) is less than 130 ms.
Genome organization of RNA tumor viruses. I. In vitro synthesis of full-genome-length single-stranded and double-stranded viral DNA transcripts (1978)

Genome-length complementary DNA (cDNA) transcripts were synthesized in vitro by using purified virions of avian myeloblastosis virus. Moloney murine leukemia virus, and clone 124 mouse sarcoma virus. The size of the genomelenth cDNA transcripts was measured on either alkaline sucrose gradients or alkaline agarose gels. The longest cDNA transcripts synthesized by using avian myeloblastosis virus, Moloney murine leukemia virus, and clone 124 mouse sarcoma virus were 7, 9 and 6 kilobases (kb), respectively. The in vitro system used was capable of synthesizing double-stranded DNA, but the plus strands (same polarity as the viral RNA) were only 0.5 to 1.5 kb long. Lone Moloney murine leukemia virus cDNA transcripts were used as templates to synthesize the second plus strand. Essentially two strategies were employed as follows. (i) The 3' ends of the cDNA transcripts were extended by addition of 50 to 100 dAMP residues by terminal deoxynucleotidyl transferase. The (dA)n-tailed cDNA transcripts were used as templates along with an oligomer of dT as primer and Escherichia coli DNA polymerase to synthesize the plus strands. (ii) DNase-digested calf thymus DNA was used to prime the synthesis of plus strands on long cDNA with E. coli DNA polymerase I. In both cases, the synthesis of the plus strands was monitored by increased resistance of the cDNA templates to single-strand-specific S1 nuclease. The double-stranded DNA was fractionated on neutral sucrose gradients. Analysis of the double-stranded DNA synthesized by using oligo(dT) primer showed the plus strands to be about 5 to 6 kb long, whereas the plus strands synthesized by using DNase-digested calf thymus DNA primers were only 0.3 to 0.5 kb long. Double-stranded DNA synthesized by either method has an average size of 6 x 10(6) daltons. Double-stranded DNA was also synthesized by using cDNA transcripts as templates without the addition of any primers. In this case, the plus strands were covalently linked to the template strand and were not representative of the whole parent strand.
Electronics development of silicon microdisplay for virtual reality applications (1999)

We have developed a highly integrated liquid-crystal-on-silicon microdisplay for virtual reality applications. The silicon display panel was designed and fabricated by a custom 0.5 /spl mu/m 3-metal CMOS technology. We further utilized field programmable gate array to implement a color sequential technique for driving this display panel. 4 bits per color of the display was demonstrated. The use of FPGA has advantages of fast prototyping and flexible in-circuit reconfiguration for different display applications. This compact microdisplay system can lead to a variety of virtual reality applications.
A three-dimensional simulation of quantum transport in silicon nanowire transistor in the presence of electron-phonon interactions (2006)

Based on the nonequilibrium Green’s function formalism, we have developed a three-dimensional (3D) simulation framework capable of handling electronic transport in nanoscale silicon devices within the effective mass and Hartree approximations. Using the deformation potential theory and the self-consistent Born approximation, we obtain the spatially local self-energy functions for the intravalley and intervalley phonon scattering mechanisms. To make the 3D simulation practicable, we reduce the computational complexity by using the mode space approach suitable for the device whose cross section is relatively uniform along the transport direction. We also obtain the expression for the phonon-limited low field mobility in the long channel limit from the linear response theory. As an application, we study the quantum transport of the silicon nanowire transistor whose channel length is 15nm in the ballistic limit and in the presence of the electron-phonon interactions. We can observe various effects of the electron-phonon interactions such as the reduction of the drain current, broadening of the local density of states, and the energy relaxation of the electrons injected from the source.
Dark blood late enhancement imaging (2016)

Free-breathing, dark blood PSIR LGE imaging was demonstrated to improve the visualization of subendocardial MI and fibrosis in cases with low contrast with adjacent blood pool. The proposed method also improves visualization of thin walled fibrous structures such as atrial walls and valves, as well as papillary muscles.
Vacancy, Search, and Prices in a Housing Market Matching Model (1990)

A model of the single-family housing market is proposed in which households that move are both buyers and sellers. Households move when a stochastic process leaves them dissatisifed with their current unit. Household buyers expend costly search effort to find a better house, while sellers hold two units until a buyer is found. The vacancy rate, fixed in the short run, determines the expected length of sale and search, which play a central role in the reservation prices of buyer and seller. Market prices, the result of bargaining, lie between these two. The model yields a strong theoretical relationship (inverse) between vacancy and prices, which with competitive supply explains the existence of longer-run "structural" vacancy. Copyright 1990 by University of Chicago Press.
Molecular characterization of rat NKR-P2, a lectin-like receptor expressed by NK cells and resting T cells (1998)

The gene for a rat NK lectin-like receptor (NKLLR), named NKR-P2, has been cloned and characterized. Sequence analysis shows that it represents the orthologue of human NKG2D and that the two molecules form a distinct NKLLR family, no more related to NKG2A/B, -C or -E than to other NKLLR families. Nkrp2 is a single-copy gene containing seven introns, mapping to the rat NK gene complex. Rat NKR-P2 differs from the human orthologue in that its cytoplasmic tail contains 13 additional amino acids, encoded by a separate exon. Splice variants lacking this exon were not detected in T cells or NK cells. NKR-P2 is strongly expressed by NK cells. In contrast to other NKLLR, it is also strongly expressed by resting thoracic duct CD4+ and CD8+ T cells, but not by thymocytes or other hemopoietic cells.