gebhart/patrepeval huggingface dataset:
Nucleotide Sequence of cDNA Coding the Mitochondrial Precursor Protein of the ATPase Inhibitor from Humans (1999)

Mitochondrial ATP synthase (F1Fo-ATPase) is regulated by an intrinsic ATPase inhibitor protein. In the present study, cDNA coding the human homolog of the inhibitor protein was isolated and sequenced. The deduced protein sequence shows that the protein was composed of 106 amino acids and had a molecular weight of 12248. The structural features of the protein show that the cDNA isolated in this study codes the human ATPase inhibitor.
A new electron beam patterning technology for 0.2μm VLSI (1985)

The validity of e-beam direct writing technology for 0.5μm VLSI lithography has been demonstrated through 1'bit DRAM fabrication(l). Further extension of this technology to quartermicron VLSI lithography can be achieved by minimizing the degradation of resolution caused by the proximity effect from scattered electrons and beam edge resolution. One aproach to limiting the effect of these factors is using a patterning technique which transfers precisely a beam image to a resist.
Caffeine effects on marksmanship during high-stress military training with 72 hour sleep deprivation. (2003)

During periods of sleep deprivation combined with other stressors, the use of 200 or 300 mg of caffeine enabled SEAL trainees to sight the target and pull the trigger faster without compromising shooting accuracy.
Quadratic-inverse spectrum estimates: applications to palaeoclimatology (1990)

Abstract This paper describes some new methods for the analysis of time series and their application to find new results in palaeoclimate. The new statistical theory includes a quadratic inverse theory for unbiased estimation of power spectra, an associated test for spectral resolution, maximum-likelihood spectrum estimates, and detailed explanations of some topics in the detection and estimation of periodic components. A new technique for estimating transfer functions is described. This methodology is used to analyse series describing global ice volume over the past 700000 years as recorded by proxy oxygen isotope ratios from deep-sea cores. We find many of the periodic components predicted by the Milankovitch theory. However, systematic departures are found from the predicted frequencies. These are accompanied by phase modulation that can be attributed to changes in the precession constant of the Earth caused by glaciation-induced changes in the Earth’s principal moments. An estimate of the transfer function from ice volume to precession implies that the Earth’s crust requires more than 160000 years to compensate for mass redistribution, and overcompensates with a delay of about 24000 years.
Ultrasonic cataract extraction with acoustic horn. (1975)

An ultrasonic lens-disintegrations system is added to the aspiration side of an irrigation-aspiration system. It incorporates an acoustic horn of which one part is a stainless steel cone 4 cm long with a 1 cm diameter base. From the apex of the cone projects the other part, viz. a 22 gauge needle, which is inserted into the anterior chamber at the limbus temporally (left eye) and which carries aspirated lens fragments with saline out into a duct drilled 2 cm into the cone along its axis. At that point the duct turns at right-angles to leave the cone; a polythene tube connects the duct with the aspiration syringe. A vibration generator (sandwich transducer) initiates ultrasonic vibrations which the needle-cone combination magnifies about 100-fold at the tip of the needle. Saline input to and output from the anterior chamber are maintained exactly equal (and simultaneous) by means of a 'push-pull' system of twin reciprocating hand-driven 30 ml. syringes (Fig. 7). Saline input is through a 25 gauge needle at the limbus at 6 o'clock (left eye).
Tau Alternative Splicing and Frontotemporal Dementia (2005)

A number of neurodegenerative diseases are characterized by the presence of abundant deposits containing Tau protein. Expression of the human tau gene is under complex regulation. Mutations in the tau gene have been identified in patients with frontotemporal lobe dementia. These mutations affect either biochemical/biophysical properties or the delicate balance of different splicing isoforms. In this review, we summarize recent advances in our understanding of genetics and molecular pathogenesis of tauopathies with the focus on frontotemporal lobe dementia. We review published studies on tau pre-mRNA splicing regulation. Understanding molecular mechanisms of tauopathies may help in developing effective therapies for neurodegenerative tauopathies and related disorders, including Alzheimer disease.
A nuclear survey instrument with imaging capability (1992)

A nuclear survey instrument with an imaging capability is being developed for remotely locating high-level radioactive sources with minimal operator exposure. It combines an image of the distribution of radioactivity with a video image of the area containing the source. allowing rapid remote location of the source. The nuclear imaging system is based on a position sensitive photomultiplier tube and a diverging hole collimator. The design and measured performance of a prototype device are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Literature Analysis of Prognostic Factors for Response and Quality of Response of Patients with Renal Cell Carcinoma to Interleukin-2-Based Therapy (2001)

Response rates were highest in trials utilizing interleukin-2 combinations. Longer median survivals were associated with high percentages of patients with nephrectomy, good performance status, with publication year, response rates, and inversely with median ages. Associations of performance status and prior nephrectomy with response rates were detected in trials with individual patient details. The response rate was higher for patients older than the median age of patients entering each trial, and also higher for males. Among responders, attainment of complete response was associated with fewer sites of involvement. Pooled response duration of patients reported to have complete responses exhibited durability, but no correlation with prognostic factors. Selection factors may have influenced apparent differences between types of regimens. We confirm the potential for durable remissions from interleukin-2-based regimens.
A multilevel relaxation algorithm for simultaneous localization and mapping (2005)

This paper addresses the problem of simultaneous localization and mapping (SLAM) by a mobile robot. An incremental SLAM algorithm is introduced that is derived from multigrid methods used for solving partial differential equations. The approach improves on the performance of previous relaxation methods for robot mapping, because it optimizes the map at multiple levels of resolution. The resulting algorithm has an update time that is linear in the number of estimated features for typical indoor environments, even when closing very large loops, and offers advantages in handling nonlinearities compared with other SLAM algorithms. Experimental comparisons with alternative algorithms using two well-known data sets and mapping results on a real robot are also presented.
Clostridium butyricum in combination with specific immunotherapy converts antigen-specific B cells to regulatory B cells in asthmatic patients (2016)

The effect of antigen specific immunotherapy (SIT) on asthma is supposed to be improved. Published data indicate that administration of probiotics alleviates allergic diseases. B cells play important roles in the pathogenesis of allergic diseases. This study aims to modulate antigen specific B cell property by the administration of Clostridium butyrate (CB) in combination with SIT. The results showed that after a 3-month treatment, the total asthma clinical score and serum specific IgE were improved in the patients treated with SIT, which was further improved in those treated with both SIT and CB, but not in those treated with CB alone. Treatment with SIT and CB increased p300 and STAT3 activation, up regulated the IL-10 gene transcription and increased the frequency of peripheral antigen specific B cells. In conclusion, administration with SIT in combination with CB converts Der p 1 specific B cells to regulatory B cells in asthma patients allergic to Der p 1. The data suggest a potential therapeutic remedy in the treatment of allergic diseases.
Internationalizing software with concurrent engineering (1995)

Today's global markets and multinational networks demand the simultaneous release of applications in many languages. Concurrent engineering offers a solution to this challenge, if the benefits of a potential market can be successfully balanced against the risk of untried technologies. The authors present a framework of options for doing so.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Comparison of New High Capacity Ion Exchange Silicas of the Spherosil Type and Normal Microparticulate Ion Exchangers of the Polystyrene Divinylbenzene Type in High Performance Liquid Chromatography (1977)

Synthesis methods, properties, and applications of a new series of microparticulate ion exchange silicas are discussed. Strong and weak cation and anion silicas have been prepared. These packings are stable from pH 2 to 9, are rigid, and have high exchange capacities (up to 2.2 meq.g−1). They are compared to classical resin-based materials. Similar separations are obtained but with greater speed since higher flow rates and pressures may be used.
Earthquake Damage Assessment of Buildings Using VHR Optical and SAR Imagery (2010)

Rapid damage assessment after natural disasters (e.g., earthquakes) and violent conflicts (e.g., war-related destruction) is crucial for initiating effective emergency response actions. Remote-sensing satellites equipped with very high spatial resolution (VHR) multispectral and synthetic aperture radar (SAR) imaging sensors can provide vital information due to their ability to map the affected areas with high geometric precision and in an uncensored manner. In this paper, we present a novel method that detects buildings destroyed in an earthquake using pre-event VHR optical and post-event detected VHR SAR imagery. The method operates at the level of individual buildings and assumes that they have a rectangular footprint and are isolated. First, the 3-D parameters of a building are estimated from the pre-event optical imagery. Second, the building information and the acquisition parameters of the VHR SAR scene are used to predict the expected signature of the building in the post-event SAR scene assuming that it is not affected by the event. Third, the similarity between the predicted image and the actual SAR image is analyzed. If the similarity is high, the building is likely to be still intact, whereas a low similarity indicates that the building is destroyed. A similarity threshold is used to classify the buildings. We demonstrate the feasibility and the effectiveness of the method for a subset of the town of Yingxiu, China, which was heavily damaged in the Sichuan earthquake of May 12, 2008. For the experiment, we use QuickBird and WorldView-1 optical imagery, and TerraSAR-X and COSMO-SkyMed SAR data.
EXPLOSIVES—A SURVEY OF TECHNICAL ADVANCES (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEXPLOSIVES—A SURVEY OF TECHNICAL ADVANCESMelvin A. CookCite this: Ind. Eng. Chem. 1968, 60, 7, 44–55Publication Date (Print):July 1, 1968Publication History Published online1 May 2002Published inissue 1 July 1968https://pubs.acs.org/doi/10.1021/ie50703a006https://doi.org/10.1021/ie50703a006research-articleACS PublicationsRequest reuse permissionsArticle Views227Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Efficient dynamic spectrum access implementation (2010)

Shared Spectrum Company developed Dynamic Spectrum Access (DSA) technology that enables military radio communication systems to deliver robust, non-interrupted wireless connectivity to tactical networks technology. DSA allows network operators to adapt to last minute spectrum assignment planning changes as well as changes made after deployment. DSA also allows the radios to overcome even unplanned, unexpected interference sources. The technology was initially developed for the DARPA XG program, and now several military radio platforms are currently being extended to integrate the technology. We present a case study of dynamic spectrum access software technical and operational integration challenges. We also present the benefits from developing and deploying a single core radio software application that follows commercial iPhone-like solutions. We describe an approach that obviates many problems by abstracting radio components into a set of device classes. We also define an open application-programming interface for interacting between the device classes and the dynamic spectrum access components. We have defined an open management interface for allowing consistent spectrum management across all platforms. This approach supports a scalable proliferation of the technology, future enhancements across platforms, and provides compatible spectrum management paradigm across platforms. This also enables upgrades performed in a consistent fashion. Our experience and results show that the approach performs well across heterogeneous military radio platforms with vastly varied hardware and software features. This software-only extension is achieved via adaptively collecting, analyzing, and responding to radio's spectral environment at runtime. This paper is a case study of lessons learned, challenges with network and waveform integration, and a roadmap for other dynamic access spectrum developers to consider in future applications.
Shortening formulation and control (1978)

Abstract Shortening provides a significant and increasing proportion of total fat in the diet. Functional and nutritional requirements have contributed significantly to the evolution of formulation and unit processing technology required to produce such products. Evolution of these changes and the effect on shortening requirements are reviewed. Basic structural considerations as well as practical processing characteristics are elucidated. Finally, the effect of such changes on the quality control of shortening manufacture is considered.
Disrupting the Interaction Between HOX and PBX Causes Necrotic and Apoptotic Cell Death in the Renal Cancer Lines CaKi-2 and 769-P (2008)

Our findings suggest that the HOX/PBX dimer is a potential therapeutic target in renal cancer.
A Video Coding Scheme Based on Joint Spatiotemporal and Adaptive Prediction (2009)

We propose a video coding scheme that departs from traditional Motion Estimation/DCT frameworks and instead uses Karhunen-Loeve Transform (KLT)/Joint Spatiotemporal Prediction framework. In particular, a novel approach that performs joint spatial and temporal prediction simultaneously is introduced. It bypasses the complex H.26x interframe techniques and it is less computationally intensive. Because of the advantage of the effective joint prediction and the image-dependent color space transformation (KLT), the proposed approach is demonstrated experimentally to consistently lead to improved video quality, and in many cases to better compression rates and improved computational speed.
Study of the Phase-Lock Phenomenon for a Circular Slingatron (2002)

Abstract : The phase-lock phenomenon of a mass sled sliding along in a circular slingatron is studied both numerically and analytically. Parameters that describe a slingatron, in which the phase angle of the swing arms increases quadratically in time, are found to be simply related to the sled's speed during phase lock. The time required for phase lock to occur is related to a simple exponential function of the gyration speed and the coefficient of friction between the sled and track. Accurate time histories describing the motion of the accelerating sled are expressed in terms of confluent hypergeometric functions 1F1. These results are then used to obtain physical insight into why the phase-lock phenomenon takes place and to describe the important role that friction plays by damping the oscillatory motion of the sled.
A Direct Comparison of Human Papillomavirus Type 16 L1 Particles Reveals a Lower Immunogenicity of Capsomeres than Viruslike Particles with Respect to the Induced Antibody Response (2008)

Capsomeres are considered to be an alternative to viruslike particle (VLP)-based vaccines as they can be produced in prokaryotic expression systems. So far, no detailed side-by-side comparison of VLPs and capsomeres has been performed. In the present study, we immunized mice with insect cell-derived human papillomavirus type 16 VLPs and capsomeres. VLPs induced consistently higher antibody titers than capsomeres but the two forms induced similar CD8 T-cell responses after subcutaneous, intranasal, and oral immunization, and at least 20 to 40 times more L1 in the form of capsomeres than in the form of VLPs was needed to achieve comparable antibody responses. These results were confirmed by DNA immunization. The lower immunogenicity of capsomeres was independent of the isotype switch, as it was also observed for the early immunoglobulin M responses. Although there were differences in the display of surface epitopes between the L1 particles, these did not contribute significantly to the differences in the immune responses. capsomeres were less immunogenic than VLPs in Toll-like receptor 4 (TLR4)-deficient mice, suggesting that the lower immunogenicity is not due to a failure of capsomeres to trigger TLR4. We observed better correlation between antibody results from enzyme-linked immunosorbent assays and neutralization assays for sera from VLP-immunized mice than for sera from capsomere-immunized mice, suggesting qualitative differences between VLPs and capsomeres. We also showed that the lower immunogenicity of capsomeres could be compensated by the use of an adjuvant system containing MPL. Taken together, these results suggest that, presumably because of the lower degree of complexity of the antigen organization, capsomeres are significantly less immunogenic than VLPs with respect to the humoral immune response and that this characteristic should be considered in the design of putative capsomere-based prophylactic vaccines.
The potential therapeutic gain of radiation-associated gene therapy with the suicide gene cytosine deaminase (2000)

Increases in tumour control of 20 to 40% can be expected, which should be detectable in a 2-arm randomized trial of 260 (for 20%) or 60 (for 40%) patients.
Expert system support using Bayesian belief networks in the diagnosis of fine needle aspiration biopsy specimens of the breast. (1994)

The further development of such a system will have three important roles in breast cytodiagnosis: (1) to aid the cytologist in making a more consistent and objective diagnosis; (2) to provide a teaching tool on breast cytological diagnosis for the non-expert; and (3) it is the first stage in the development of a system capable of automated diagnosis through the use of expert system machine vision.
Drag on Nonspherical Objects (1987)

Stokes's law describes drag force on a sphere in creeping flow. This law can be extended to a nonspherical object by allocating the interaction of the fluid with the object into its interaction with two analogous spheres, one with the same projected area and one with the same surface area as the object. This approach was used to characterize dynamic shape factor for objects whose shape factors are reported in the literature. Agreement between data and the equation for shape factor based on this approach was excellent for prisms: R 2 = 0.998. This equation and empirical equations from the literature were used to predict shape factor for a sphere, cylinders, prisms, spheroids, and double conicals whose shape factors have been reported. The equation based on the Stokes's law extension predicted shape factors better than the empirical equations, as judged by a least-squares index of performance.
The Clinical study of plasma lysophosphatidic acid in patients with acute coronary syndromes (2003)

Objective To study the level of plasma lysophosphatidic acid(LPA) in patients with acute coronary syndromes(ACS).Methods 120 patients with ACS were devided into two groups:group AMI(AMI) 60 and group unstable angina(UAP) 60(before treatment UAP 1 and after treatment UAP 2),and 60 healthy persons served as control.LPA was extracted from plasma of patients.Results Plasma LPA levels of AMI and UAP 1 were 3.8017±0.6289 μmol/L and 3.0273±0.7623 μmol/L respectively,significantly higher than that in control group(1.8378±0.6753 μmol/L),P0.05.The plasma LPA level of UAP decreased significantly after anticoagulant and antiplatelet treatment(2.0048±0.8470 μmol/L).Conclusion As a molecular marker released by activated platelet in vivo,plasma LPA may be valuable for predicting the occurrence and development of ACS and guiding the treatment.
Selected Plastics Wear Resistance to Bonded Abrasive Particles Compared to Some Ferrous Materials (2015)

Plastics are macromolecular materials without we cannot imagine any branch of human activity with. Plastics have unique properties, often very different from metals. At the choice of the concrete plastic for the concrete application it is necessary to evaluate its mechanical, physical, chemical and technological properties. In last years producers offer also plastics for production of parts exposed to different types of wear. In the contribution the results of wear resistance studying of 10 types of plastics (PTFE, PVC, POM-C, PC, PETP, PEEK, PA66, PP, PA6E and PE-UHMW) of one producer are published and compared with test results of four different Fe alloys (grey iron, structural steel, cast steel wear resistant and high-speed steel). The laboratory tests were carried out using the pin-on-disk machine with abrasive cloth (according to ÄSN 01 5084), when the abrasive clothes of three different grits (240, 120 and 60) were used. It corresponds to the average abrasive grain sizes of 44.5 µm, 115.5 µm and 275 µm. During the test the test sample was pressed to the abrasive cloth by the pressure of 0.1 MPa. The wear intensity was assessed by the volume, weight and length losses of tested samples. The technical-economical evaluation was the part of the carried out tests. It was univocally proved that at the intensive abrasive wear using the abrasive cloth the best results shows the High-Speed Steel HSS Poldi Radeco 19 810 according to ÄSN 41 9810, although its price is relatively high. Other tested Fe alloys, namely grey iron according to ÄSN 42 2415, structural steel 11 373 according to ÄSN 41 1373 and wear resistant cast steel VPH 6 showed also very favourable properties at the material low price. In comparison with Fe alloys the wear of all plastics was considerably higher and the plastics were considerably more expensive.