gebhart/patrepeval huggingface dataset:
Structural Polymer-Based Carbon Nanotube Composite Fibers: Understanding the Processing–Structure–Performance Relationship (2013)

Among the many potential applications of carbon nanotubes (CNT), its usage to strengthen polymers has been paid considerable attention due to the exceptional stiffness, excellent strength, and the low density of CNT. This has provided numerous opportunities for the invention of new material systems for applications requiring high strength and high modulus. Precise control over processing factors, including preserving intact CNT structure, uniform dispersion of CNT within the polymer matrix, effective filler-matrix interfacial interactions, and alignment/orientation of polymer chains/CNT, contribute to the composite fibers' superior properties. For this reason, fabrication methods play an important role in determining the composite fibers' microstructure and ultimate mechanical behavior. The current state-of-the-art polymer/CNT high-performance composite fibers, especially in regards to processing-structure-performance, are reviewed in this contribution. Future needs for material by design approaches for processing these nano-composite systems are also discussed.
Highly Efficient Hydrosilylation of Diyne and Triyne π-Electron Bridges:  Its Application to Fluorescent Dyes and Silylene-Spaced Vinylarene Compounds (2004)

A variety of diyne and triyne π-electron bridges were hydrosilylated to afford the bis- and tris(silylvinyl) π-electron bridges. The hydrosilylation products underwent substitution reactions with a variety of compounds containing chromophore units to give fluorescent dye substituted products. The easy access of the silyl hydrides may be applied to construct a large number of copolymers.
An E3 ubiquitin ligase: c-Cbl (2011)

To the best of the authors' knowledge, the current study is the first to demonstrate that c-Cbl WT protein overexpression inhibits tumor metastasis and tumor growth in lung cancer xenograft models. These results provide evidence that ectopic expression of c-Cbl WT protein can be potentially applied as targeted therapy for the treatment of lung cancer.
Changes in pulse pressure variability during cardiac resynchronization therapy in mechanically ventilated patients (2007)

Changes in cardiac performance have a significant impact on respiratory hemodynamic fluctuations in ventilated patients. This influence should be taken into consideration when interpreting PP variation.
The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site. (1994)

The mammalian spliceosome-associated protein, SAP 49, is associated specifically with U2 snRNP and is the most efficiently UV cross-linked protein in the spliceosomal complexes A, B, and C. We show here that SAP 49 cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in the prespliceosomal complex A. In addition to the RNA-binding activity of SAP 49, we show that this protein interacts directly and highly specifically with another U2 snRNP-associated spliceosomal protein, SAP 145. We have isolated a cDNA-encoding SAP 49 and find that it contains two amino-terminal RNA-recognition motifs (RRMs), consistent with the observation that SAP 49 binds directly to pre-mRNA. The remainder of the protein is highly proline-glycine rich (39% proline and 17% glycine). Unexpectedly, the SAP 49-SAP 145 protein-protein interaction requires the amino-terminus of SAP 49 that contains the two RRMs. The observation that SAP 49 and SAP 145 interact directly with both U2 snRNP and the pre-mRNA suggests that this protein complex plays a role in tethering U2 snRNP to the branch site.
Elucidation of the mechanism of selective inhibition of mammalian DNA polymerase alpha by 2-butylanilinopurines: development and characterization of 2-(<i>p</i>-n-butylanilino) adenine and its deoxyribonucleotides (1985)

2-(p-n-Butylanilino)adenine (BuAA), an homolog of the DNA polymerase alpha (pol alpha)-specific inhibitor, N2-(p-n-butylphenyl)guanine (BuPG), was transformed to its 2'-deoxyribonucleoside, BuAdA, and the corresponding 2'-deoxyribonucleoside 5'-phosphates, BuAdAMP, BuAdADP, and BuAdATP. All five forms of BuAA are highly selective inhibitors of mammalian pol alpha, and the action of each is subject to specific competitive antagonism by dATP. BuAdADP, and BuAdATP, like the corresponding forms of BuPG, are very potent pol alpha inhibitors, displaying apparent Ki's of less than 3 nanomolar on natural activated templates. BuAdATP, like BuPdGTP, also inhibits pol alpha-catalysed reactions directed by non-complementary, thymine-deficient templates, and it does so via a mechanism subject to specific antagonism by its natural homolog, dATP. The results of the BuAdATP-homopolymer experiments complement those of analogous experiments with BuPdGTP and the dCTP-specific pol alpha inhibitor, aphidicolin, and strengthen the suggestion that mammalian pol alpha contains dNDP and dNTP binding sites which can recognize specific bases without direction by templates.
The Utilization of a Holographic Bragg Diffraction Filter for Rayleigh Line Rejection in Raman Spectroscopy (1990)

Raman spectra have been observed to within less than 200 cm −1 of the Rayleigh line through the use of a holographic Bragg diffraction (HBD) filter. The HBD filter has a very high optical density (5.8 OD) while maintaining a relatively high and flat transmission in the region >200 cm −1 . Utilization of an HBD filter allowed the observation of Raman spectra with a compact 0.125-mm spectrograph. Spectra of solid, liquid, and surface-enhanced Raman (SER) samples have been demonstrated with the HBD Raman system.
Moderate sleep deprivation produces impairments in cognitive and motor performance equivalent to legally prescribed levels of alcohol intoxication (2000)

These findings reinforce the evidence that the fatigue of sleep deprivation is an important factor likely to compromise performance of speed and accuracy of the kind needed for safety on the road and in other industrial settings.
Expression of pax-6 during urodele eye development and lens regeneration. (1995)

Regeneration of eye tissues, such as lens, seen in some urodeles involves dedifferentiation of the dorsal pigmented epithelium and subsequent differentiation to lens cells. Such spatial regulation implies possible action of genes known to be specific for particular cell lineages and/or axis. Hox genes have been the best examples of genes for such actions. We have, therefore, investigated the possibility that such genes are expressed during lens regeneration in the newt. The pax-6 gene (a gene that contains a homeobox and a paired box) has been implicated in the development of the eye and lens determination in various species ranging from Drosophila to human and, because of these properties, could be instrumental in the regeneration of the urodele eye tissues as well. We present data showing that pax-6 transcripts are present in the developing and the regenerating eye tissues. Furthermore, expression in eye tissues, such as in retina, declines when a urodele not capable of lens regeneration (axolotl) surpasses the embryonic stages. Such a decline is not seen in adult newts capable of lens regeneration. This might indicate a vital role of pax-6 in newt lens regeneration.
Reaction of 5-Substituted 2-(3-Chloropropanoylamino)benzophenone syn- and anti-Oximes with Sodium Hydroxide (2005)

Treatment of syn-oximes of 5-substituted 2-(3-chloropropanoylamino)benzophenones with equimolar amount of sodium hydroxide results in formation of syn-oximes of 5-substituted 2-propenoylamino-benzophenones. The corresponding anti isomers under the same conditions give a mixture of anti-oximes of 5-substituted 2-(propenoylamino)benzophenones and 18-membered 11,22-disubstituted 7,8,18,19-tetrahydrodibenzo[d,m][1,10,2,6,11,15]dioxatetraazacyclooctadecine-6,17(5H,16H)-diones.
Detection of reticulated platelets: estimating the degree of fluorescence of platelets stained with thiazole orange (2000)

The primary problem in the measurement of reticulated platelets (RP) stained with thiazole orange (TO) by flow cytometry is the definition of a threshold limit for fluorescence positivity. We evaluated settings for the threshold gate for TO positivity based on two principles: a fluorescence histogram (median FL1, Relative FL1) or a plot of forward light scatter (FSC; reflecting the distribution of the platelet size) versus fluorescence intensity (% RP). These methods were applied prospectively in examination of 54 healthy blood donors (16 females) and a total of 50 blinded patient samples: pregnant women with thrombocytopenia (Group 1A, n = 11), thrombocytopenic women after delivery (Group 1B, n = 9) and healthy women with a thrombocytopenic newborn (Group 2, n = 30). Group 1A displayed higher median FL1 (mean 306, CI 279-332) as compared to that of Group 2 (mean 266, CI 255-277; p = 0.0038) or to that of the female controls (mean 249, CI 231-268; p < 0.001). Relative FL1 was also higher in the patients of Group 1A than those of Group 2 (p = 0.037). When analysing the % RP, the difference between these groups was not significant. In the patients (n = 50), the median FSC (mean 407, SD 40, CI 395-418) was also higher than that of the controls (n = 54; mean 383, SD 25, CI 376-390; Mann-Whitney U-test, p = 0.0015). In Group 1A, a significant correlation was observed between the Patient median FL1 and Patient median FSC (r = 0.62, p = 0.043). When developing methods for the measurement of RP, it seems to be useful to analyse the data with more than one principle to define the threshold limit for TO positivity.
Improvement of gait by chronic, high doses of methylphenidate in patients with advanced Parkinson's disease (2006)

Chronic, high doses of MPD improved gait and motor symptoms in the absence of L-dopa and increased the intensity of response of these symptoms to L-dopa in a population with advanced PD.
Classification of Middle Aged Women's Breast Shapes Using 3D Body Measurement Data (2010)

The breast types of middle-aged women of 80A (formerly 80B) size were classified through a 3D scanned nude body. Thirty seven measurements including the radius of curvature, surface area, volume, surface length, and breast displacements were used as input variables. We extracted five main factors through the factor analysis of the measurements and classified 36 subjects into 3 clusters through the cluster analysis. As a result of the factor analysis, the size of the breast, breast sag, the curvature of the inner and the outer breast curve, the width of the breast, and the nipple direction were found as the main factors. For the results of the classification of breast types, Cluster 1 was characterized by narrow breast width and unsymmetrical under the breast curve, whereas Cluster 2 was a wide and sagged shape. Cluster 3 was classified into big breast volume and symmetrical under-breast curve. The results are useful to the product development of high quality brassieres which reflect the 3D characteristics of breast types of middle-aged women.
Clinical outcomes of vertical bone augmentation to enable dental implant placement: a systematic review (2008)

For the concept of vertical ridge augmentation to enable dental implant placement, there are clinical and histological data supporting its potential use. Given the confined number of investigators using these techniques and the low number of patient treatments reported in the literature, the generalizability of this approach is limited at this time.
Steady-state thermo-optic model of a continuous-wave Raman laser (2002)

We present a model of a cw Raman laser that includes thermo-optic effects that are due to the heating that is inherent in Raman conversion. Thermal lensing and thermal index gratings at high output powers are addressed. With a quadratic duct model we show that broadening of the spatial modes is evident at low Stokes output powers and that accounting for thermal lensing in the laser design can significantly enhance the conversion efficiency. The model agrees with experimental results from a cw H2 Raman laser and allows for the design of high-power and solid-state cw Raman lasers.
Signatures of Drug Sensitivity in Nonsmall Cell Lung Cancer (2011)

We profiled receptor tyrosine kinase pathway activation and key gene mutations in eight human lung tumor cell lines and 50 human lung tumor tissue samples to define molecular pathways. A panel of eight kinase inhibitors was used to determine whether blocking pathway activation affected the tumor cell growth. The HER1 pathway in HER1 mutant cell lines HCC827 and H1975 were found to be highly activated and sensitive to HER1 inhibition. H1993 is a c-MET amplified cell line showing c-MET and HER1 pathway activation and responsiveness to c-MET inhibitor treatment. IGF-1R pathway activated H358 and A549 cells are sensitive to IGF-1R inhibition. The downstream PI3K inhibitor, BEZ-235, effectively inhibited tumor cell growth in most of the cell lines tested, except the H1993 and H1650 cells, while the MEK inhibitor PD-325901 was effective in blocking the growth of KRAS mutated cell line H1734 but not H358, A549 and H460. Hierarchical clustering of primary tumor samples with the corresponding tumor cell lines based on their pathway signatures revealed similar profiles for HER1, c-MET and IGF-1R pathway activation and predict potential treatment options for the primary tumors based on the tumor cell lines response to the panel of kinase inhibitors.
Effect of microwave plasma treatment on silicon dioxide films grown by atomic layer deposition at low temperature (2013)

The effects of microwave plasma treatments on the physical and electrical characteristics of silicon dioxide films are discussed. Plasma treatments significantly improve the characteristics at low temperatures. Differences in the type of inert gas, O2 partial pressure, and total pressure cause differences in the plasma energy and active species concentrations, which affect reduction in the impurity concentrations, generation of dangling bonds, and effective working depth of the plasma. The changes in the electrical characteristics of the plasma-treated oxide films are consistent with those in the physical characteristics. The plasma conditions that result in the best improvements are determined.
Methoxypyridines in the Synthesis of <i>Lycopodium</i> Alkaloids: Total Synthesis of (±)-Lycoposerramine R (2010)

A methoxypyridine serves as a masked pyridone in a concise synthesis of the Lycopodium alkaloid lycoposerramine R, which has been prepared for the first time. The key step of the synthesis is the use of an Eschenmoser Claisen rearrangement to forge a key quaternary carbon center.
Negotiation Behaviors Based on Artificial Intelligence and Social and Cognitive Human-Agent Interaction (2008)

Behaviors, in which the characters such as conciliatory (Con), neutral (Neu), or aggressive (Agg) define a 'psychological' aspect of the human personality, play an important role for negotiation agent. Elsewhere, learning in negotiation is fundamental for understanding human behaviors as well as for developing new solution concepts. In this paper, a brief description of SISINE (Integrated System of Simulation for Negotiation) project, which aims to develop innovative teaching methodology of negotiation skills, is given. Then, a negotiation strategy essentially based on negotiation behaviors of the human personality is suggested for SISINE. Such negotiation behaviors which are based on the characters Con, Neu, and Agg, and acquired first by reinforcement learning (Q-learning, and Sarsa-Learning) approaches, and second by Neural Networks (NN) are then developed. From this, the suggested strategy is developed and the negotiation behavior results presented. The suggested strategy displays the ability to provide agents, through a basic buying strategy, with a first intelligence level.
Neonatal Lipopolysaccharide Exposure Exacerbates Stress-Induced Suppression of Luteinizing Hormone Pulse Frequency in Adulthood (2007)

Early life exposure to immunological challenge has programming effects on the adult hypothalamo-pituitary-adrenocortical axis stress responsivity, and stress is known to suppress GnRH pulse generator activity, especially LH pulses. We investigated the effects of neonatal exposure to endotoxin on stress-induced suppression of pulsatile LH secretion and the involvement of corticotropin-releasing factor (CRF) receptor mechanisms in adult rats. Pups at 3 and 5 d of age were administered lipopolysaccharide (LPS, 50 microg/kg, ip). At 12 wk of age, they were ovariectomized and implanted with sc 17beta-estradiol capsules and i.v. cannulas. Blood samples (25 microl) were collected every 5 min for 5 h for LH measurement. After 2 h of sampling, rats were given LPS (25 microg/kg, iv). CRF and CRF-R1 and CRF-R2 receptor mRNA was determined by RT-PCR in medial preoptic area (mPOA) micropunches collected at 3 h after LPS administration. There was no difference in basal LH pulse frequency between neonatal LPS- and neonatal saline-treated controls. However, neonatal endotoxin-treated rats exhibited a significantly greater LPS stress-induced suppression of LH pulse frequency. Basal mPOA CRF-R1 expression was unchanged in neonatal LPS- and neonatal saline-treated rats. However, CRF-R1 expression was significantly increased in response to LPS stress in neonatal LPS-treated animals but not in neonatal saline-treated controls. CRF and CRF-R2 expression was unchanged in all treatment groups. These data demonstrate that exposure to bacterial endotoxin in early neonatal life programs long-term sensitization of the GnRH pulse generator to the inhibitory influence of stress in adulthood, an effect that might involve up-regulation of CRF-R1 expression in the mPOA.
Chemische Reaktionen in Flüssigkeitsringpumpen (1966)

Abstract Flüssigkeitsringpumpen sind deshalb für Gas/Flüssigkeitsreaktionen besonders ge‐eignet, weil die Pumpe gleichzeitig die Reaktionspartner ansaugt und fördert, auf den gewünschten Reaktionsdruck bringt, als Absorptionsmaschine wirkt und als Reaktionsraum dient. Außerdem lassen sich bei labilen, nur unter Verlusten komprimierbaren Gasen durch die Anwesenheit des Reaktionspartners während der Kompression Zerfalls‐ und Nebenreaktionen verhindern. — An der großtechnischen Herstellung von Essigsäureanhydrid aus Keten und Essigsäure wird neben anderen Vorteilen gezeigt, daß durch eine Einheit, bestehend aus Pumpe und Reaktinskühler, ganze Wäscheranlagen ersetzt werden können.
Self- regulated learning and time perspectives as predictors of academic performance (2016)

The goal of this study was to research the hypotheses that self-regulated learning (SRL) and time perspectives predict academic performance in second year Economics studies. In the theoretical underpinning self-regulated learning and time perspectives as concepts are clarified, and explored as related to academic performance. Data was analysed using descriptive, correlation analysis and hierarchical regression. A correlation matrix and hierarchical regression revealed that a relationship exists between different aspects of SRL, the future time perspective and academic performance. In conclusion the study recommended that teaching and learning methods should be used to empower students to apply self-regulated learning strategies and to be focused on the future. This could greatly enhance their academic performance.
Prediction intelligence in context-aware applications (2005)

Mobile applications are required to operate in ubiquitous environments of dynamic nature. Specifically, the availability of resources and services may vary significantly during a typical session of system operation. As a consequence, mobile applications need to be capable of adapting to these changes to ensure the best possible level of service to the user. Therefore, such adaptive applications may have pre-evaluated the appropriate knowledge of their environment to act efficiently. Such knowledge is not known a priori, so information prediction and proactivity should enhance and extend the functionality of such applications in order to be adaptable to the future changes of their underlying computational environment. In this paper, we discuss and evaluate such a context prediction algorithm.
<i>THLASPI CAERULESCENS</i> J. & C. PRESL. (<i>T. ALPESTRE</i> L.) IN BRITAIN (1986)

Thlaspi caerulescens J. & C. Presl. (T. alpestre L.) has a restricted and disjunct distribution in Britain. Both on natural and mine sites it is confined to soils contaminated by lead and zinc. Morphological variation occurs both regionally and locally but there is no support from a taxometric cluster analysis for the taxonomic recognition of variants. In experiment the index of zinc tolerance of plants raised from seed was positively correlated with the concentration of zinc in the soils from which the seed parents originated. The distribution of T. caerulescens is discussed in relation to morphological and physiological variation between populations.
CCII.—The iodination of phenols and the iodometric estimation of, and action of reducing agents on, tannic acid (1909)

W. M. Gardner and H. H. Hodgson, J. Chem. Soc., Trans., 1909, 95, 1819 DOI: 10.1039/CT9099501819
Management of 1-D Sequence Data- From Discrete to Continuous (1999)

Data over ordered domains such as time or linear positions are termed sequence data. Sequence data require special treatments which are not provided by traditional DBMSs. Modelling sequence data in traditional (relational) database systems often results in awkward query expressions and bad performance. For this reason, considerable research has been dedicated to supporting sequence data in DBMSs in the last decade. Unfortunately, some important requirements from applications are neglected, i.e., how to support sequence data viewed as continuous under user-defined interpolation assumptions, and how to perform subsequence extraction efficiently based on the conditions on the value domain. We term these kind of queries as value queries (in contrast to shape queries that look for general patterns of sequences). This thesis presents pioneering work on supporting value queries on 1-D sequence data based on arbitrary user-defined interpolation functions. An innovative indexing technique, ter...
Product Selection Policies for Perishable Inventory Systems (1990)

A comparison is made of the performance characteristics of perishable inventory systems with LIFO and FIFO selection policies. For each system one has Poisson arrivals to inventory and Poisson demand epochs with known rates and deterministic shelf life. The comparison requires development of a new analytical framework for the LIFO systems and extension of earlier results on the FIFO systems via Green's function methods. The performance characteristics derived for both policies are spoilage rate, loss sales rate, mean time between stockouts, inventory level on hand and the distribution of age of items delivered. In particular, the dependance of these characteristics on the replenishment rate, demand rate and shelf life are evaluated both theoretically and numerically. Several important management implications are explored and discussed.