gebhart/patrepeval huggingface dataset:
Using Geometry to Detect Grasps in 3D Point Clouds (2015)

This paper proposes a new approach to detecting grasp points on novel objects presented in clutter. The input to our algorithm is a point cloud and the geometric parameters of the robot hand. The output is a set of hand configurations that are expected to be good grasps. Our key idea is to use knowledge of the geometry of a good grasp to improve detection. First, we use a geometrically necessary condition to sample a large set of high quality grasp hypotheses. We were surprised to find that using simple geometric conditions for detection can result in a relatively high grasp success rate. Second, we use the notion of an antipodal grasp (a standard characterization of a good two fingered grasp) to help us classify these grasp hypotheses. In particular, we generate a large automatically labeled training set that gives us high classification accuracy. Overall, our method achieves an average grasp success rate of 88% when grasping novels objects presented in isolation and an average success rate of 73% when grasping novel objects presented in dense clutter. This system is available as a ROS package at http://wiki.ros.org/agile_grasp.
Chemical shift imaging with phase‐encoding RF pulses (1992)

An inherent problem of conventional chemical shift imaging is signal contamination into adjacent voxels. This is especially severe in proton spectroscopy of the central nervous system, where the lipid signal from the skull is several orders of magnitude higher than the metabolite resonances from the brain. The reason for the contamination lies in the fact that the distribution of spins does not coincide with the discrete sampling matrix of the discrete Fourier transformation if a continuous phase-encoding scheme using magnetic field gradients is being used. This problem can be overcome if phase encoding is performed by appropriately phase-modulated RF pulses. It is demonstrated that contamination free spectra can be acquired from voxels immediately adjacent to the skull. Using small voxels of 1 x 1 x 2-ml regional variations of N-acetyl aspartate in the cerebellum of patients with oligopontine cerebellar atrophy could be observed.
Ultrafast nonequilibrium carrier dynamics in semiconductor laser mode locking (2014)

Semiconductor disk lasers have been shown to be ideal as wavelength-agile, high-brightness sources for producing high average power under various pulsed mode-locking scenarios. Systematic microscopic modeling reveals that ultrafast nonequilibrium kinetic hole burning in electron/hole carrier distributions dictates the outcome of femtosecond duration mode-locked pulse formation. The existence of a large reservoir of unsaturated carriers within the inverted distributions leads to the emergence of multiple pulse waveforms (not necessarily harmonically mode-locked pulse trains) that inefficiently draw on these carrier reservoirs. The concept of gain is no longer meaningful in this limit, and the dynamical inversion of electrons and holes primarily in the active medium establishes the final dynamical state of the system. The simulation results explain much of the generic behavior observed in key recent experiments and point to the difficulty of pushing semiconductor mode-locked lasers to pulse durations below 100 fs.
Surfactant Therapy and Intracranial Hemorrhage: Review of the Literature and Results of New Analyses (1993)

Surfactant therapy may set in motion hemodynamic changes that could predispose to intracranial hemorrhage in certain circumstances, but this can probably be compensated by careful management of oxygenation and ventilation. A relationship between surfactant therapy and intracranial hemorrhage is probably not isolated to any particular surfactant preparation or method of delivery; studies comparing surfactants have shown no differences in rates of intracranial hemorrhage.
Gut T<sub>FH</sub> and IgA: key players for regulation of bacterial communities and immune homeostasis (2013)

The main function of the immune system is to protect the host against pathogens. However, unlike the systemic immune system, the gut immune system does not eliminate, but instead nourishes complex bacterial communities and establishes advanced symbiotic relationships. Immunoglobulin A (IgA) is the most abundant antibody isotype in mammals, produced mainly in the gut. The primary function of IgA is to maintain homeostasis at mucosal surfaces, and studies in mice have demonstrated that IgA diversification has an essential role in the regulation of gut microbiota. Dynamic diversification and constant adaptation of IgA responses to local microbiota require expression of activation-induced cytidine deaminase by B cells and control from T follicular helper and Foxp3(+) T cells in germinal centers (GCs). We discuss the finely tuned regulatory mechanisms for IgA synthesis in GCs of Peyer's patches and emphasize the roles of CD4(+) T cells for IgA selection and the maintenance of appropriate gut microbial communities required for immune homeostasis.
Distribution of dihydrolipoamide acetyltransferase (E2) in the liver and portal lymph nodes of patients with primary biliary cirrhosis: An immunohistochemical study (1991)

The reason for the close association between primary biliary cirrhosis and the appearance of antibodies that recognize the E2 component of pyruvate dehydrogenase complex is not understood. The distribution of the three pyruvate dehydrogenase complex subunits was examined in the liver and lymph nodes of patients with primary biliary cirrhosis, patients with other liver diseases and normal subjects by immunohistochemistry using affinity-purified antibodies. Intensity of staining was assessed semiquantitatively and validated by scanning laser confocal microscopy. In primary biliary cirrhosis tissue, the E2 staining pattern did not parallel the reported distribution of mitochondria. E2 staining in biliary epithelial cells was consistently stronger than in hepatocytes. In primary biliary cirrhotic liver, staining of biliary epithelium was significantly stronger than in normal or other liver disease controls; many bile ducts in primary biliary cirrhotic liver demonstrated very high intensity, diffuse distribution of stain. No differences in staining intensity were seen between perivenular hepatocytes in primary biliary cirrhotic liver and those in controls; periportal hepatocytes in primary biliary cirrhotic liver were, however, more intensely stained than perivenular cells. In primary biliary cirrhotic portal lymph nodes, a subset of macrophages showed high-intensity, diffuse distribution of stain. By contrast, staining with antibodies to E1 and E3 (other components of pyruvate dehydrogenase complex) produced uniform-intensity, mitochondrial distribution both in primary biliary cirrhosis and control tissue. The increased intensity of E2 in primary biliary cirrhotic tissue could be explained in terms of abnormal metabolism of E2 by biliary epithelial cells.(ABSTRACT TRUNCATED AT 250 WORDS)
Plasmonic Gold Templates Enhancing Single Cell Lipidomic Analysis of Microorganisms (2020)

Single cell lipid profiling is a powerful tool to connect membrane composition and its changes within individual cells to specific biochemical functions or stimuli, but current approaches are inadequate due to the complex nature of the cells and technical limitation in analysis. Herein we report a new method with plasmonic substrates capable of cell localization and enhanced lipid ionization through thin-gold-film MALDI-MS. We performed lipidomic profiling of algae single cells with a 120-well microarray and identified more than 50 lipids in <i>C. reinhardtii</i> without an extraction process. The substrate was used for probing toxicological effect of herbicide atrazine on the algae's lipidome, demonstrating molecular changes in glycerol lipid profiles. Fast location of cells with metal-enhanced fluorescence (MEF) and subsequent precise and direct ionization of the LDI process contribute to the enhanced performance, allowing for assessment of lipid changes concurrent with atrazine affected populations. This method that combines microarrays, MEF, and MALDI-MS presents an effective platform for lipidomic study of single cells and for environmental toxicity study with microorganisms.
Characteristics of a commercially aged nickel-molybdenum-alumina hydrotreating catalyst: component distribution, coke characteristics, and effects of regeneration (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacteristics of a commercially aged nickel-molybdenum-alumina hydrotreating catalyst: component distribution, coke characteristics, and effects of regenerationJames M. Bogdanor and Howard F. RaseCite this: Ind. Eng. Chem. Prod. Res. Dev. 1986, 25, 2, 220–230Publication Date (Print):June 1, 1986Publication History Published online1 May 2002Published inissue 1 June 1986https://pubs.acs.org/doi/10.1021/i300022a017https://doi.org/10.1021/i300022a017research-articleACS PublicationsRequest reuse permissionsArticle Views239Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The GRK4 Subfamily of G Protein-coupled Receptor Kinases (1999)

G protein-coupled receptor kinases (GRKs) desensitize G protein-coupled receptors by phosphorylating activated receptors. The six known GRKs have been classified into three subfamilies based on sequence and functional similarities. Examination of the mouse GRK4 subfamily (GRKs 4, 5, and 6) suggests that mouse GRK4 is not alternatively spliced in a manner analogous to human or rat GRK4, whereas GRK6 undergoes extensive alternative splicing to generate three variants with distinct carboxyl termini. Characterization of the mouse GRK 5 and 6 genes reveals that all members of the GRK4 subfamily share an identical gene structure, in which 15 introns interrupt the coding sequence at equivalent positions in all three genes. Surprisingly, none of the three GRK subgroups (GRK1, GRK2/3, and GRK4/5/6) shares even a single intron in common, indicating that these three subfamilies are distinct gene lineages that have been maintained since their divergence over 1 billion years ago. Comparison of the amino acid sequences of GRKs from various mammalian species indicates that GRK2, GRK5, and GRK6 exhibit a remarkably high degree of sequence conservation, whereas GRK1 and particularly GRK4 have accumulated amino acid changes at extremely rapid rates over the past 100 million years. The divergence of individual GRKs at vastly different rates reveals that strikingly different evolutionary pressures apply to the function of the individual GRKs.
Factors controlling the proliferative rate, final cell density, and life span of bovine vascular smooth muscle cells in culture. (1981)

Low density vascular smooth muscle (VSM) cell cultures maintained on extracellular-matrix(ECM)-coated dishes and plated in the presence of either plasma or serum will proliferate actively when serum-containing medium is replaced by a synthetic medium supplemented with three factors: high density lipoprotein (HDL, 250 micrograms protein/ml); insulin (2.5 micrograms/ml) or somatomedin C (10 ng/ml); and fibroblast growth factor (FGF, 100 ng/ml) or epidermal growth factor (EGF, 50 ng/ml). The omission of any of these three factors from the synthetic medium results in a lower growth rate of the cultures, as well as in a lower final cell density once cultures reach confluence. When cells are plated in the total absence of serum, transferrin (10 micrograms/ml) is also required to induce optimal cell growth. The effects of the substrate and medium supplements on the life span of VSM cultures have also been analyzed. Cultures maintained on plastic and exposed to medium supplemented with 5% bovine serum underwent 15 generations. However, when maintained on ECM-coated dishes the serum-fed cultures had a life span of at least 88 generations. Likewise, when cultures were maintained in a synthetic medium supplemented with HDL and either FGF or EGF, an effect on the tissue culture life span by the substrate was observed. Cultures maintained on plastic underwent 24 generations, whereas those maintained on ECM-coated dishes could be passaged repeatedly for 58 generations. These experiments demonstrate the influence of the ECM-substrate only in promoting cell growth but also in increasing the longevity of the cultures.
Production of Nucleic Acid-related Substances by Fermentative Processes (1968)

The accumulation of 5'-inosinic acid (IMP) by a mutant, KY 13102, induced from Brevibacterium ammoniagenes ATCC 6872 by ultraviolet light irradiation, was examined. Although growth was stimulated by adenine or adenosine, the microorganism showed fair growth in the medium containing amino acids but no adenine. Among six kinds of natural nutrients tested, meat extract and Casamino Acids were suitable for the accumulation of IMP. Manganese ion strongly affected growth, the accumulation of IMP and hypoxanthine, and cell morphology. Among amino acids tested, L-methionine, L-proline, and L-valine stimulated IMP accumulation. In the medium containing 1.0 g of L-proline per liter, 12.8 mg of IMP per ml was accumulated. The mechanism of IMP accumulation by the mutant is discussed.
Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo (2001)

There exists marked heterogeneity in action of nifedipine, efonidipine and mibefradil on the renal microvascular in canine kidneys in vivo. Furthermore, our current observations suggest an important contribution of T-type calcium channel activity to efferent arteriolar tone in vivo.
<title>The Use Of Low Power Lasers In Particle Size Spectrometry</title> (1977)

Low power gas lasers are nearly ideal light sources for particle size spectrometers. Particle size spectrometers involving imaging and light scattering have proven most satisfactory and are described in detail. The imaging spectrometers use 2 - 5 mW He-Ne lasers and a photodiode array to size and provide particle shape information on particles 1 - 10,000 μm diameter. Airborne spectrometers designed for hydrometeor measurements have 128 MHz data rate capabilities and provide full data compression. The light scattering spectrometers developed use 1 - 2 mW He-Ne lasers in both open and closed cavity sensing configurations. These instruments typically size particles with diameters less than 0.1 μm to greater than 30 μm. Methods of combining an imaging system with the light scattering methods to define the sample volume are detailed. Some possible advantages of short and multiwavelength lasers are discussed.
Alien Invaders! Post-visit Lessons, Support Materials (Grade 6) (2006)

Support material to enable students to write a public service announcement invasive species.
The Total Synthesis of (+)-Dragmacidin F (2004)

The first total synthesis of (+)-dragmacidin F has been accomplished, establishing the absolute configuration of this biologically important, antiviral marine alkaloid. The convergent route described features a palladium-mediated oxidative pyrrole carbocylization reaction to construct the [3.3.1] bicycle, as well as a highly selective Suzuki coupling to build the carbon skeleton of the natural product. A late-stage Neber rearrangement allows for the facile installation of the aminoimidazole moiety to provide (+)-dragmacidin F.
POLY: Mining Relational Paraphrases from Multilingual Sentences (2016)

Language resources that systematically organize paraphrases for binary relations are of great value for various NLP tasks and have recently been advanced in projects like PATTY, WiseNet and DEFIE. This paper presents a new method for building such a resource and the resource itself, called POLY. Starting with a very large collection of multilingual sentences parsed into triples of phrases, our method clusters relational phrases using probabilistic measures. We judiciously leverage fine-grained semantic typing of relational arguments for identifying synonymous phrases. The evaluation of POLY shows significant improvements in precision and recall over the prior works on PATTY and DEFIE. An extrinsic use case demonstrates the benefits of POLY for question answering.
Fast Intra-Network and Cross-Layer Handover (FINCH) for WiMAX and Mobile Internet (2008)

To support fast and efficient handovers in mobile WiMAX, we propose fast intra-network and cross-layer handover (FINCH) for intradomain (intra-CSN) mobility management. FINCH is a complementary protocol to mobile IP (MIP), which deals with interdomain (inter-CSN) mobility management in mobile WiMAX. FINCH can reduce not only the handover latency but also the end-to-end latency for MIP. Paging extension for FINCH is also proposed to enhance the energy efficiency. The proposed FINCH is especially suitable for real-time services in frequent handover environment, which is important for future mobile WiMAX networks. In addition, FINCH is a generic protocol for other IEEE 802-series standards. This is especially beneficial for the integration of heterogeneous networks, for instance, the integration of WiMAX and WiFi networks. Both mathematical analysis and simulation are developed to analyze and compare the performance of FINCH with other protocols. The results show that FINCH can support fast and efficient link layer and intradomain handovers. The numerical results can also be used to select proper network configurations.
Dichloroacetate restores drug sensitivity in paclitaxel-resistant cells by inducing citric acid accumulation (2015)

The abilityof DCA to target cells with mitochondrial respiratory defect and restore paclitaxel sensitivity by inducing citrate accumulation supports further preclinical development.
Homeo Domain of the Yeast Repressor α2 Is a Sequence-Specific DNA-Binding Domain But Is Not Sufficient for Repression (1987)

The alpha 2 protein, the product of the MAT alpha 2 gene, is a regulator of cell type in the yeast Saccharomyces cerevisiae. It represses transcription of a group of cell type-specific genes by binding to an operator located upstream of each target gene. Fifteen in-frame deletions within the coding region of the MAT alpha 2 gene were constructed. The deletion alleles were examined for phenotypes conferred in vivo, and the encoded mutant proteins were assayed for ability to bind specifically to the operator in vitro. This analysis has revealed that the sequence-specific DNA-binding domain of alpha 2 is located within a region of 68 amino acids. This region of alpha 2 has significant homology with the homeo domain, a conserved sequence found in the products of several Drosophila homeotic and segmentation genes. In addition, there is a class of mutant alpha 2 proteins that binds tightly and specifically to the operator in vitro, but fails to repress transcription in vivo.
DNA content of hepatocytes in various stages of liver cirrhosis (1985)

In order to search for some parameters that would make it possible to predict a potentially high risk of evolution from liver cirrhosis to hepatocellular carcinoma (HCC), the DNA content of hepatocytes in patients with liver cirrhosis with or without development to HCC was investigated by means of microspectrophotometry in Feulgen-stained specimens. In patients without development of HCC in more than 5 years of follow-up, 90% or more of tested hepatocytes were diploid, whereas in patients with liver cirrhosis who developed HCC within 3 years the frequency histogram of nuclear DNA content was widely spread from diploid to hyperpolyploid with a small peak of triploid. Furthermore, in the latter group of patients, many of the binucleate cells had different DNA contents in each paired nucleus. In non-cancerous portions of HCC, the ploidy histogram of nuclear DNA content was widely spread from diploid to polyploid with different DNA contents of each paired nucleus in binucleate cells, without the small peak of triploid. These results suggest that the deranged cell kinetics of hepatocytes in cirrhosis may be considered to be a state of potentially high risk for the evolution of HCC, and that a patient with liver cirrhosis with such an abnormal hepatocyte DNA content should be followed up carefully for the early diagnosis of HCC.
A time-correlation method of calculating nonlinearities utilizing pseudorandom sequences (1994)

A new time-correlation method of measuring nonlinearities using pseudorandom sequences is presented. The method relies on the properties of pseudorandom sequences to display nonlinearities as echoes of the main response. The size and position of these echoes correspond to the amount and the type of nonlinear effect present in the system, respectively. The accuracy of the time-correlation method was verified in simulation using Lorentzian waveforms, and with real systems. The measurement accuracy is compared to other more complex methods. The time-correlation method can be implemented with analog or digital circuits, enabling the real-time measurement of nonlinear distortions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Four-year safety follow-up of the tetravalent dengue vaccine efficacy randomized controlled trials in Asia and Latin America (2018)

The overall benefit-risk remained positive in those aged ≥9 years up to year 4, although the protective effect was lower in years 3 and 4 than in years 1 and 2.
Open and Closed-circuit Endotracheal Suctioning in Acute Lung Injury (2005)

Closed-circuit endotracheal suctioning followed by a recruitment maneuver prevents hypoxemia resulting from OES but decreases secretion removal. Increasing suctioning pressure enhances suctioning efficiency without impairing gas exchange.
Colors for textiles—Ancient and modern. (1947)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTColors for textiles—Ancient and modern.Max. Bender Cite this: J. Chem. Educ. 1947, 24, 1, 2Publication Date (Print):January 1, 1947Publication History Received3 August 2009Published online1 January 1947Published inissue 1 January 1947https://doi.org/10.1021/ed024p2RIGHTS & PERMISSIONSArticle Views534Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (7 MB) Get e-Alerts Get e-Alerts