gebhart/patrepeval huggingface dataset:
Influence of Manganese on Growth of a Sheathless Strain of <i>Leptothrix discophora</i> (1985)

Mn exerted various effects on the growth of Leptothrix discophora strain SS-1 in batch cultures depending on the concentration added to the medium. Concentrations of 0.55 to 5.5 muM Mn, comparable to those in the environment from which strain SS-1 was isolated, decreased cell yield and prolonged stationary-phase survival, but did not affect growth rate. Elevated concentrations of 55 to 910 muM Mn also decreased cell yield and prolonged survival, but growth rate was decreased as well. The addition of 1,820 muM Mn caused a decline in cell numbers followed by an exponential rise after 80 h of incubation, indicating the development of a population of cells resistant to Mn toxicity. When 360 muM Mn or less was added to growth flasks, Mn was oxidized to manganese oxide (MnO(x), where x is approximately 2), which appeared as brown particles in the medium. Quantification of Mn oxidation during growth of cultures to which 55 muM Mn was added showed that nearly all of the Mn was oxidized by the beginning of the stationary phase of growth (15 to 25 h). This result suggested that the decrease in cell yield observed at low and moderate concentrations of Mn was related to the formation of MnO(x), which may have bound cationic nutrients essential to the growth of SS-1. The addition of excess Fe to cultures containing 55 muM Mn increased cell yield to levels near those found in cultures with no added Mn, indicating that iron deprivation by MnO(x) was at least partly responsible for the decreased cell yield.
Vigabatrin Versus ACTH as First‐Line Treatment for Infantile Spasms: A Randomized, Prospective Study (1997)

Our data lend further support to the view that VGB may be considered a first-choice drug in the treatment of IS.
The Consumer Durable Replacement Buyer (1991)

A study was conducted to develop a better understanding of the timing of consumer durable good replacement purchases. The demographic characteristics, attitudes and perceptions, and search behavior of consumers who replace a product during the early and late parts of its lifetime were examined. Results based on univariate and multivariate analyses of replacement buyers of new automobiles indicate that “early” replacement buyers are more concerned with styling and image and less concerned with costs than “late” replacement buyers. Further, early replacers have higher income, but lower levels of educational achievement and occupational status, than late replacers. Late replacers engage in more search activity. Findings also suggest that marketing efforts have differential effects on the replacement buyer segments.
MUSIC REMIXING AND UPMIXING USING SOURCE SEPARATION (2016)

Current research on audio source separation provides tools to estimate the signals contributed by different instruments in polyphonic music mixtures. Such tools can be already incorporated in music production and post-production workflows. In this paper, we describe recent experiments where audio source separation is applied to remixing and upmixing existing mono and stereo music content
Slice imaging: A new approach to ion imaging and velocity mapping (2001)

In this article we present a new approach to the already popular methods of ion imaging and velocity mapping. The novelty of this approach is that the speed and angular distributions are measured directly from the images without the need of inverse Abel transformation as in the conventional approaches. This is achieved by using delayed pulsed extraction of the ions following photodissociation and positioning of the nascent products. Delayed pulsed extraction causes a sufficient velocity spread in the ion cloud such that the time width of the ion packet at the detector is on the order of 500 ns. By using a narrow detector time gate (&lt;40 ns) we are able to image only the center slice of the ion packet. The result is equivalent to that obtained by conventional methods using the inverse Abel transform, however, the artificial noise introduced by this transform is eliminated. The energy resolution of the new approach is at least comparable to that achieved with the velocity mapping technique.
A three-component coupling protocol for the synthesis of substituted hexahydropyrrolo[3,2-c]quinolines (1999)

R. A. Batey, P. D. Simoncic, D. Lin, R. P. Smyj and A. J. Lough, Chem. Commun., 1999, 651 DOI: 10.1039/A809614G
Genetic aspects of childhood epilepsy (1989)

The extensive studies pertinent to these problems cannot be elaborated here. We have restricted ourselves to a few representative concepts, which can be summarized as follows. The genetic aspects of convulsibility and epilepsy are highly complex phenomena. The level of convulsibility is determined by a number of different excitatory (and inhibitory) genetic factors. None of these factors is strictly specific to epilepsy. Each one is only a partial aspect of a complex genetic constitution which is strikingly common in perfectly healthy individuals, and which is related to a variety of psychic and somatic particularities. Almost all of these genetic factors seem to be polygenetically determined; in other words, they seem to reflect the actions of many genes. An increased liability to convulsions, and, finally, to epilepsy, is induced by an accumulation of these factorial sets, and, of course, by the effects of exogenous lesional factors. Special constellation of these polygenic sets may lead to the manifestation of different epileptic syndromes and may also explain the segregation of seizure types in the descendants of patients with seemingly uniform epileptic syndromes, as observed, for instance, in absence epilepsy and in juvenile myoclonic epilepsy.
Deviation analysis through model checking (2002)

Inaccuracies, or deviations, in the measurements of monitored variables in a control system are facts of life that control software must accommodate $the software is expected to continue functioning correctly in the face of an expected range of deviations in the inputs. Deviation analysis can be used to determine how a software specification will behave in the face of such deviations in data from the environment. The idea is to describe the correct values of an environmental quantity; along with a range of potential deviations, and then determine the effects on the outputs of the system. The analyst can then check whether the behavior of the software is acceptable with respect to these deviations. In this report we wish to propose a new approach to deviation analysis using model checking techniques. This approach allows for more precise analysis than previous techniques, and refocuses deviation analysis from an exploratory analysis to a verification task, allowing us to investigate a different range of questions regarding a system's response to deviations.
Preparation of water-soluble multi-walled carbon nanotubes by Ce(IV)-induced redox radical polymerization (2009)

Poly(acrylic acid), poly(N-isopropylacrylamide) and polyacrylamide functionalized MWNTs were prepared by Ce(IV)-induced redox radical polymerization. The reaction can be conducted in aqueous media at room temperature, and the polymer graft ratio increased with the increase of monomer feed ratio. MWNTs anchored with PAA on the surface are pH sensitive and exhibit a reversible assembly–deassembly response in aqueous solution, whereas those coated with PNIPAM are thermally sensitive. All the polymer-functionalized MWNTs are highly soluble in water to give robust stable black solutions. Such water-soluble MWNTs are promising for biological and biomedical applications.
Transcription of Eukaryotic tRNA Genes (2014)

This chapter reviews the basis for the current view of eukaryotic tRNA promoters and transcription machinery, and discusses studies of mechanistic and regulatory strategies. Recent insights into the nature of the polymerase III transcription machinery give substance to these speculations and suggest a specific role for 5' flanking promoter elements. The discussion of the polymerase III transcription machinery first focuses on the two traditional factor fractions TFIIIB and TFIIIC and then on individual components recently resolved from these fractions. In the discussion, standard TFIIIB and TFIIIC nomenclature are used, but, keeping the heterogeneity of these fractions in mind, “F” are taken to mean “fraction” rather than “factor.” Also, it may be useful to avoid assumptions and consider the transcriptionally active polypeptides in these fractions as independent transcription factors, rather than as tightly associated subunits. Given the number of macromolecules involved in class III transcription, genetic approaches are likely to be essential for identifying all of the players. An intriguing focus of current work is the regulation of tRNA transcription. There are now a number of examples of enhanced production of particular tRNAs in response to cellular differentiation and growth conditions.
Failure to Consolidate the Consolidation Theory of Learning for Sensorimotor Adaptation Tasks (2004)

An influential idea in human motor learning is that there is a consolidation period during which motor memories are transformed from a fragile to a permanent state, no longer susceptible to interference from new learning. The evidence supporting this idea comes from studies showing that the motor memory of a task (A) is lost when an opposing task (B) is experienced soon after, but not if sufficient time is allowed to pass (approximately 6 hr). We report results from three laboratories challenging this consolidation idea. We used an ABA paradigm in the context of a reaching task to assess the influence of experiencing B after A on the retention of A. In two experiments using visuomotor rotations, we found that B fully interferes with the retention of A even when B is experienced 24 hr after A. Contrary to previous reports, in four experiments on learning force fields, we also observed full interference between A and B when they are separated by 24 hr or even 1 week. This latter result holds for both position-dependent and velocity-dependent force fields. For both the visuomotor and force-field tasks, complete interference is still observed when the possible affects of anterograde interference are controlled through the use of washout trials. Our results fail to support the idea that motor memories become consolidated into a protected state. Rather, they are consistent with recent ideas of memory formation, which propose that memories can shift between active and inactive states.
Gastric mucosal cell proliferation during development in rats and effects of pentagastrin (1982)

Changes in cell proliferation and cell loss in the gastric mucosa were examined during the first 4 wk of life. The effect of pentagastrin on these parameters before and after weaning was also investigated. The results revealed that DNA content of mucosa and lumen increased with age. However, when luminal DNA (an assessment of cell loss) content was expressed as percent of total mucosal DNA (referred to as percent cell loss), an inverse relationship with age was observed. The rate of mucosal DNA synthesis, measured in vitro, was found to remain elevated up to the age of 15 days and then dropped dramatically within the next 5--6 days after which it decreased slowly. The rate of mucosal DNA synthesis in 5- to 15-day-old rats was found to be 10--15 times higher than in 20- to 30-day-old rats. In 10-day-old suckling young, mucosal thymidine kinase activity was also found to be higher than in 20- to 28-day-old rats. On the other hand, total incorporation of [3H]thymidine into mucosal DNA per stomach was found to be significantly greater in 21- to 28-day-old weaned rats than in the 10-day-old suckling young. Multiple injections of pentagastrin to 28-day-old rats significantly increased mucosal DNA synthesis and thymidine kinase activity by 43 and 200%, respectively, and cell loss by 30% when compared with the saline control. The hormone did not affect DNA synthesis, thymidine kinase, or cell loss in 10-day-old rats. There were considerable increases in 20-day-old rats that were not statistically significant due to the variation of the data.
Ras Promotes Growth by Alternative Splicing-Mediated Inactivation of the KLF6 Tumor Suppressor in Hepatocellular Carcinoma (2008)

Our findings expand the role of Ras in human HCC by identifying a novel mechanism of tumor-suppressor inactivation through increased alternative splicing mediated by an oncogenic signaling cascade.
Lifetime of Electrolytic Capacitors in Regenerative Induction Motor Drives (2006)

Electrolytic capacitors are normally used as the energy storage element in the DC link of voltage-source converters because of their high density. Unfortunately, they are bulky and their lifetime is significantly reduced by their operating temperatures. Thus, reducing, or even better eliminating, the amount of electrolytic capacitors is an important goal since the capacitor could be a single point of failure. This paper analyses the lifetime of electrolytic capacitors used in the DC link of an induction motor (IM) drive whose front end consists of a controlled rectifier. The latter controls the DC-link voltage and input power factor. Both, the inverter and rectifier operate under space vector modulation (SVM). The peak ripple voltage, ripple current, core temperature and lifetime of electrolytic capacitors ranging from 200 muF to 12000 muF are calculated for different values of the source inductance and the ambient temperature when the IM is operating at rated load. In addition, the IM ripple torque and speed response time are also calculated and an 8.2 muF ceramic capacitor case is included for completeness. The evaluation is based on Matlabtrade/Simulink simulation results of the IM drive that are used to calculate harmonic components of the different current waveforms. The results show that the lifetime of electrolytic capacitors is significantly reduced for decreasing capacitance values. The main reason is that the effective series resistance (ESR), and hence heat losses, increases for decreasing capacitance values leading to increased core temperatures that are detrimental to the capacitor lifetime
Research on the Supplementary Analysis System Based on CPS Standard (2012)

CPS test standard has put forward new demands to the management of power grids. This paper analyzes the main influence factors of CPS, and introduces the way of building data warehouse and constructing supplementary analysis system on this basis, which can effectively help power grid workers to research the pros and cons in dispatch and operation. The application of the supplementary analysis system is helpful for Shanghai power grid to enhance AGC control and frequency control ability under the control performance standard.
Activity of XL184 (Cabozantinib), an Oral Tyrosine Kinase Inhibitor, in Patients With Medullary Thyroid Cancer (2011)

Cabozantinib has an acceptable safety profile and is active in MTC. Cabozantinib may provide clinical benefit by simultaneously targeting multiple pathways of importance in MTC, including MET, VEGFR2, and RET. A global phase III pivotal study in MTC is ongoing (ClinicalTrials.gov number NCT00215605).
New 24-pulse diode rectifier systems for utility interface of high power AC motor drives (2002)

This paper proposes two new passive 24-pulse diode rectifier systems for utility interface of PWM AC motor drives. The first approach employs an extended delta transformer arrangement which results in near equal leakage inductance in series with each diode rectifier bridge. This promotes equal current sharing and improved performance. A specially tapped interphase reactor is then introduced with two additional diodes to extend the conventional 12-pulse operation to 24-pulse operation from the input current point of view. The proposed system exhibits clean power characteristics with 5th, 7th, 11th, 13th, 17th and 19th harmonics eliminated from the utility line currents. The second scheme is a reduced kVA approach employing autotransformers to obtain 24-pulse operation. The kVA rating of the polyphase transformer in the second scheme is 0.18 P/sub o/ (PU). Detailed analysis and simulations verify the proposed concept and experimental results from a 208 V, 10 kVA rectifier system are provided.
Using tries to eliminate pattern collisions in perfect hashing (1994)

Many current perfect hashing algorithms suffer from the problem of pattern collisions. In this paper, a perfect hashing technique that uses array-based tries and a simple sparse matrix packing algorithm is introduced. This technique eliminates all pattern collisions, and, because of this, it can be used to form ordered minimal perfect hashing functions on extremely large word lists. This algorithm is superior to other known perfect hashing functions for large word lists in terms of function building efficiency, pattern collision avoidance, and retrieval function complexity. It has been successfully used to form an ordered minimal perfect hashing function for the entire 24481 element Unix word list without resorting to segmentation. The item lists addressed by the perfect hashing function formed can be ordered in any manner, including alphabetically, to easily allow other forms of access to the same list.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
ON THE FREQUENCY DISTRIBUTION OF THE MEANS OF SAMPLES FROM A POPULATION HAVING ANY LAW OF FREQUENCY WITH FINITE MOMENTS, WITH SPECIAL REFERENCE TO PEARSON'S TYPE II (1927)

Journal Article ON THE FREQUENCY DISTRIBUTION OF THE MEANS OF SAMPLES FROM A POPULATION HAVING ANY LAW OF FREQUENCY WITH FINITE MOMENTS, WITH SPECIAL REFERENCE TO PEARSON'S TYPE II Get access J. O. IRWIN, M.A., M.Sc. J. O. IRWIN, M.A., M.Sc. Search for other works by this author on: Oxford Academic Google Scholar Biometrika, Volume 19, Issue 3-4, December 1927, Pages 225–239, https://doi.org/10.1093/biomet/19.3-4.225 Published: 01 December 1927
Water Distribution Analysis in the Outer Perimeter Region of Technical PEFC Based on Neutron Radiography (2015)

This work focuses on water transport behavior in PEFC, particularly in the area situated between flowfield and sealing gasket. An in situ investigation of fundamental water and gas transport effects in this edge region was performed by means of neutron radiography. Five different 50 cm2 test cell setups were operated, basically differing in the applied sealing solution, whereby it was accounted for the requirements posed by metallic bipolar plates. Main influencing factors on the water transport were identified, namely channel geometry, gas inlet humidification, temperature and gas pressure under static and dynamic conditions. It was found that the design of the edge region can have a significant influence on water transport properties and water accumulation in the cell. Depending on\nits gas accessibility, the edge region can act as a reservoir for water accumulation. Time constants for water transport can be shifted\nto the range of hours, which is crucial for an effective water removal as it is essential for cold starts. In addition, relatively wide edge channels, as required for sub-gasket based cell setups, can enable strong bypass flows around the flowfield and thus lower the effective stoichiometry, which can have a significant impact on the water content in the flowfield.
Quantitative Morphology Characterization of New PC-siloxane Copolymer Blends (2014)

SABIC recently developed polycarbonate-polysiloxane (PC-siloxane) copolymer blends which offer unique combinations of chemical resistance and low temperature impact ductility compared to polycarbonate (PC) homo-polymers. These novel blends have additional excellent aesthetic properties at high polysiloxane levels in the blend, especially when compared to polycarbonate-polysiloxane copolymers with the same polysiloxane content In PC-siloxane copolymer blends, siloxane forms nano-domains and is dispersed in the PC matrix. As the siloxane nano-domain size and the dispersion have a significant influence on the material properties, it is critical to develop quantitative morphology characterization
PRACTICAL PLATFORM (2009)

RETURN TO ISSUEPREVNewsNEXTPRACTICAL PLATFORMAdimab believes its yeast-based ANTIBODY DISCOVERY SYSTEM could change how biotherapeutics are foundLISA M. JARVISView Author Information C&EN NORTHEAST NEWS BUREAUCite this: Chem. Eng. News 2009, 87, 30, 34–36Publication Date (Print):July 27, 2009Publication History Published online15 November 2010Published inissue 27 July 2009https://pubs.acs.org/doi/10.1021/cen-v087n030.p034https://doi.org/10.1021/cen-v087n030.p034newsACS PublicationsCopyright © 2009 AMERICAN CHEMICAL SOCIETYArticle Views9Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Biopolymers,Immunology,Peptides and proteins Get e-Alerts
Diffusion Pipes in Silicon NPN Structures (1969)

Diffusion pipes in silicon NPN structures were investigated both by electrical measurements and by microsectioning. It was found that certain crystalline defects, specifically stacking faults and edge dislocations, can act as sites for the formation of such pipes. The presence of gold doping at these lattice defects greatly increases the incidence of pipes, apparently by offering a path of enhanced diffusivity for phosphorus from the emitter.
Wastewater Reclamation at South Tahoe Public Utilities District (1968)

This article reports on a unique project in wastewater reclamation at South Lake Tahoe, California. In 1961, large‐scale pilot plant studies were conducted at South Tahoe on chemical coagulation, mixed‐media (or coarse‐ to‐fine) filtration with polyelectrolyte filter aid, and granular carbon adsorption. It was found that the process not only increased removal of BOD, COD, suspended solids, bacteria, and other substances, but also removed color, odor, colloids, viruses, phosphates, ABS, and other organic chemicals that are relatively unaffected by secondary treatment. In 1963, the South Tahoe Public Utilities District (PUD) commissioned a 2.5 mgd tertiary plant that incorporated these processes, including facilities for thermal regeneration of granular activated carbon for flows up to 10 mgd. In February 1964, further studies were begun on coagulant recovery and reuse, nitrogen removal, and data collection in connection with full‐scale carbon regeneration and reuse. In 1966, the capacity of the entire South Tahoe plant was expanded from 2.5 to 7.5 mgd, with an addition of facilities for coagulant recovery and reuse (with lime as the coagulant) and for the incineration of all sludge produced. In addition, a 7.5‐mgd ammonia stripping tower for nitrogen removal is in the design stage.