gebhart/patrepeval huggingface dataset:
Clinical experience with respiratory syncytial virus vaccines (2003)

Respiratory syncytial virus (RSV) infection is at times associated with life-threatening lower respiratory tract illness in infancy. Severe infection during the first year of life may be an important risk factor or indicator for the development of asthma in early childhood. Severe infections primarily occur in healthy infants, and young infants and children with specific risk factors. However, RSV causes respiratory infections in all age groups. Indeed it is now recognized that RSV disease is responsible for significant morbidity and mortality in the geriatric population. RSV infection remains difficult to treat, and prevention is a worldwide goal. For this reason there has been an intensive effort to develop an effective and safe RSV vaccine. Initial infection with RSV affords limited protection to reinfection, yet repeated episodes decrease the risk for lower respiratory tract illness. In the 20 years from 1960 to 1980, trials of several candidate RSV vaccines failed to attain the desired safety and protection against natural infection. Some vaccine types either failed to elicit immunogenicity, as with the live subcutaneous vaccine, or resulted in exaggerated disease on natural exposure to the virus, as with the formalin-inactivated (FI) type. Currently vaccine candidates are being developed based on the molecular virology of RSV. Recent formulations of candidate RSV vaccines have focused on subunit vaccines [such as purified fusion protein (PFP)], subunit vaccines combined with nonspecific immune activating adjuvants, live attenuated vaccines (including cold passaged, temperature-sensitive or cpts mutants), genetically engineered live attenuated vaccines and polypeptide vaccines.
Network security policy for large-scale VPN (2004)

In the current VPN, manual security policy configuration is usually inefficient and error-prone. The paper studies the problem of conflicts among policies in different domains of a large-scale VPN. In this paper, a new trusted domain and a novel security transmission model as the fundament of the security theory of VPN are defined, and based on them, the exact definition of security transmission requirements and the corresponding effective security policies for a large-scale VPN are proposed. In addition, this paper gives the principles of policy verification for the purpose of checking the consistence of security policies in the whole network environment.
Robust object tracking (1995)

We describe an object tracker robust to a number of ambient conditions which often severely degrade performance, for example partial occlusion. The robustness is achieved by describing the object as a set of related geometric primitives (lines, conics, etc.), and using redundant measurements to facilitate the detection of outliers. This improves the overall tracking performance. Results are given for frame rate tracking on image sequences.
The Application of wireless LANS in mine automation (2002)

This work reports variations in the yields and quality of volatiles produced from Eucalyptus citriodora leaves by different hydrodistillation (HD) and supercritical carbon dioxide extraction (SCE) techniques. HD techniques (1.5%) produced higher yields compared to SCE (0.7%). Citronellal, the major component, was maximum in the extract produced by SCE (79%) followed by oil produced by water-steam distillation (WSD) (72.6%) and water distillation (WD) (62.4%) techniques. Chemical composition of glycoside-bound volatiles produced by acid hydrolysis during HD was found to be very different from free volatiles, although in a minor quantity. The extent of artefact formation and release of aglycones was more profound in the bound volatile oil produced by WD than WSD. Highest oxygenated monoterpenes were found in SCE and WSD (93% each) followed by WD (91.4%). Although the SCE produced lower yields than the HD techniques, its extract is superior in quality in terms of higher concentration of citronellal.
Driving and Side Task Performance: The Effects of Display Clutter, Separation, and Modality (2004)

In-vehicle technologies (IVTs) create additional tasks for the driver. To the extent that these devices degrade driving performance, there will be safety concerns. This study examines the effects of display clutter from overlay, display separation, and modality on driving and IVT task performance. In a fixed-base simulator, 22 drivers drove different routes and responded to infrequent, unexpected road hazards while engaging in a phone number task presented by different displays. Visual displays were located on a head-up (overlaid on the visual horizon or adjacently, just above the vehicle hood) or head-down display (HDD) located near the midconsole. Alternatively, digits were presented auditorily. In general, there were no differences in performance for the adjacent and overlay displays; however, there were costs associated with the HDD and auditory display for some measures. In particular, responses to hazard events were slowed when drivers used the HDD. Overall, the adjacent display best supported performance on all relevant tasks. Potential applications of this research include the design of IVTs with respect to location and modality.
Machine learning for colour Palette extraction from fashion runway images (2020)

An important aspect of colour forecasting is the process of generating colour palettes to represent collections at fashion shows. Humans have traditionally done this manually, and can do it well, but there are often too many images and it becomes an unmanageable task. In this paper, automatic machine-learning methods are developed to generate colour palettes for a fashion show based on the runway images. A set of ground-truth data to test the models was constructed based on asking each of 22 participants to select three colours to represent each of the 48 images from a particular fashion show. A close agreement was shown between these data and the colours automatically generated using a model that incorporated both supervised and unsupervised machine learning. The work could be extended to analyse millions of images from social media feeds to provide data-driven insights for colour forecasting.
Interim estimates of influenza vaccine effectiveness in 2012/13 from Canada’s sentinel surveillance network, January 2013 (2013)

The 2012/13 influenza season in Canada has been characterised to date by early and moderately severe activity, dominated (90%) by the A(H3N2) subtype. Vaccine effectiveness (VE) was assessed in January 2013 by Canada's sentinel surveillance network using a test-negative case-control design. Interim adjusted-VE against medically attended laboratory-confirmed influenza A(H3N2) infection was 45% (95% CI: 13-66). Influenza A(H3N2) viruses in Canada are similar to the vaccine, based on haemagglutination inhibition; however, antigenic site mutations are described in the haemagglutinin gene.
Realization of Maxwell's Hypothesis (2003)

Two similar and parallel Ag-O-Cs surfaces in a vacuum tube ceaselessly eject electrons at room temperature. A static magnetic field applied to the tube plays the role of 'Maxwell's demon'. The thermal electrons are so controlled by the magnetic field that they can travel only from one Ag-O-Cs surface to the other, resulting in collections of positive and negative charge on the two surfaces, respectively, as well as an electric potential between the two surfaces. A load, a resistance outside of the tube for example, is connected by wires to the two surfaces, continuously receiving electric power from the tube. The ambient air is a single heat reservoir in this situation, and all of the heat extracted by the tube from the air is converted to electric energy, without producing any other effect. The authors believe that the experiment is in contradiction to Kelvin's statement, and that the famous hypothesis proposed by Maxwell about 140 years ago is realized.
Adverse effects of bisphosphonates: current issues. (2008)

Four bisphosphonates are used for the treatment of metastatic bone disease: clodronate, which is available outside the United States in both intravenous and oral formulations; intravenous pamidronate; intravenous zoledronic acid; and ibandronate, which is also available in intravenous and oral forms. Since the use of bisphosphonates in patients with cancer is palliative, their impact on patients' quality of life and their adverse-effect profiles are essential considerations for effective patient management. The most common adverse effects associated with bisphosphonates are renal toxicity, acute-phase reactions, gastrointestinal (GI) toxicity, and osteonecrosis of the jaw (ONJ). The incidence of these adverse events varies significantly between bisphosphonates. Renal toxicity is a potentially life-threatening event reported in studies of zoledronic acid and, to a lesser extent, pamidronate. In contrast, the renal safety profile of intravenous ibandronate and oral bisphosphonates is similar to that of placebo. Acute-phase reactions occur only with intravenous aminobisphosphonates and may be more common with zoledronic acid. Gastrointestinal effects occur only with oral agents (clodronate and ibandronate) and may be avoided by adhering to dosing instructions. More recently, ONJ has recently emerged as a complication of bisphosphonate use. However, its true incidence is not yet known. The potential adverse effects of bisphosphonates should be considered in the context of the individual patient's characteristics and preferences when selecting a bisphosphonate for metastatic bone disease.
The Accelerating Effect of <scp>CaSO</scp> <sub>4</sub> Within <scp>CMAS</scp> ( <scp>CaO</scp> – <scp>MgO</scp> – <scp>Al</scp> <sub>2</sub> <scp>O</scp> <sub>3</sub> – <scp>SiO</scp> <sub>2</sub> ) and Its Effect on the Infiltration Behavior in <scp>EB</scp> ‐ <scp>PVD</scp> 7 <scp>YSZ</scp> (2016)

Infiltration and deposition of Ca SO 4 in thermal barrier coatings ( TBC ) in addition to the CMAS deposits was found in many occasions on real aviation engines. The source and role of Ca SO 4 on the degradation of TBC is not well understood. Ca SO 4 containing CMAS was synthesized and a systematic study of its role on the CMAS infiltration behavior in EB ‐ PVD 7 YSZ is presented in this work. Its influence on the melting and crystallization behavior of CMAS was studied with the help of differential scanning calorimetry. The decomposition of Ca SO 4 into CaO and SO 3 was observed at 1050°C in laboratory air under the presence of CMAS using mass spectroscopy and in situ high‐temperature XRD . The same amount of CaO is brought into the CMAS system by means of adding Ca CO 3 , which will eventually decompose into CaO and CO 2 at 700°C. CMAS infiltration tests were carried out at different temperatures with and without Ca SO 4 /Ca CO 3 and the results demonstrate that the sulfur has no direct effect on the aggressiveness of the anhydrite containing CMAS with regard to its infiltration behavior in EB ‐ PVD 7 YSZ at high temperatures. The extra amount of calcia added to CMAS that is introduced by the evaporating species is responsible for enhanced infiltration of the deposits into the TBC .
IV SEMINARIO DE PROGRAMACION PRESUPUESTARIA (1980)

DURANTE EL IV SEMINARIO UNIVERSITARIO DE PROGRAMACION PRESUPUESTARIA SE DIERON A CONOCER LAS POLITICAS; PROCEDIMIENTOS Y MECANISMOS QUE REGIRAN PARA LA FORMULACION DEL ANTEPROYECTO DE PRESUPUESTO QUE SE EJERCERA EN 1981 EN LA UNAM; Y SE MARCARON LAS PAUTAS PARA QUE LA PROPIA EJECUCION PRESUPUESTARIA SEA OPORTUNA Y PERMITA LA EVALUACION PERIODICA DE LOS RESULTADOS FISICOS Y FINANCIEROS QUE SE OBTENGAN EN EL TRANSCURSO DEL PROXIMO ANO. AL EVENTO ASISTIERON SECRETARIOS ADMINISTRATIVOS Y JEFES DE UNIDADES ADMINISTRATIVAS DE ESTA CASA DE ESTUDIOS. EL INGENIERO GERARDO FERRANDO BRAVO; SECRETARIO GENERAL ADMINISTRATIVO DE LA UNAM; PRECISO LAS POLITICAS INSTITUCIONALES QUE EN MATERIA PRESUPUESTARIA REGIRAN EN 1981. SE MENCIONAN LAS PRIORIDADES EN LAS AREAS DOCENTE; DE INVESTIGACION; EXTENSION UNIVERSITARIA Y APOYO ADMINISTRATIVO. INTERVINIERON TAMBIEN EL ACTUARIO CUAUHTEMOC VALDES; DIRECTOR GENERAL DE PLANEACION; Y EL LICENCIADO ALBERTO MENENDEZ GUZMAN; DIRECTOR GENERAL DEL PRESUPUESTO POR PROGRAMAS.
Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous‐Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases (2009)

A library of resorcylic acid lactones (RAL) containing a cis-enone moiety targeting kinases bearing a cysteine residue within the ATP-binding pocket was prepared using a fluorous-mixture synthesis and evaluated against a panel of 19 kinases thus providing important structure-activity trends. Two new analogues were then profiled for their selectivity against a panel of 402 kinases providing the broadest evaluation of this pharmacophores' selectivity.
Protein Tyrosine Phosphatase Receptor Type γ Is a JAK Phosphatase and Negatively Regulates Leukocyte Integrin Activation (2015)

Regulation of signal transduction networks depends on protein kinase and phosphatase activities. Protein tyrosine kinases of the JAK family have been shown to regulate integrin affinity modulation by chemokines and mediated homing to secondary lymphoid organs of human T lymphocytes. However, the role of protein tyrosine phosphatases in leukocyte recruitment is still elusive. In this study, we address this issue by focusing on protein tyrosine phosphatase receptor type γ (PTPRG), a tyrosine phosphatase highly expressed in human primary monocytes. We developed a novel methodology to study the signaling role of receptor type tyrosine phosphatases and found that activated PTPRG blocks chemoattractant-induced β2 integrin activation. Specifically, triggering of LFA-1 to high-affinity state is prevented by PTPRG activation. High-throughput phosphoproteomics and computational analyses show that PTPRG activation affects the phosphorylation state of at least 31 signaling proteins. Deeper examination shows that JAKs are critically involved in integrin-mediated monocyte adhesion and that PTPRG activation leads to JAK2 dephosphorylation on the critical 1007-1008 phosphotyrosine residues, implying JAK2 inhibition and thus explaining the antiadhesive role of PTPRG. Overall, the data validate a new approach to study receptor tyrosine phosphatases and show that, by targeting JAKs, PTPRG downmodulates the rapid activation of integrin affinity in human monocytes, thus emerging as a potential novel critical regulator of leukocyte trafficking.
Synthesis and thermal behaviour of mesomorphic Cu II Schiff's base complexes (1991)

Three series of Schiff's bases, namely 2-(4-alkoxy-2-hydroxybenzylideneamino)fluorenes (1), 4-(4-alkoxy-2-hydroxybenzylideneamino)biphenyls (2), 4-(4-alkoxy-2-hydroxybenzylideneamino)stilbenes (3), (where the number of carbon atoms in the alkoxy chain, n, varies from 4 to 10) and the corresponding CuII complexes (4, 5 and 6, respectively) have been synthesized. The thermal behaviour of all the ligands and the complexes was investigated by means of polarizing microscopy and differential scanning calorimetry. While the ligands exhibit both nematic and smectic mesophases, the CuII complexes exhibit only a smectic mesophase. The electronic and emission spectra are also presented.
Physico-Chemical Properties and the Degradation of Oat Bran Polysaccharides in the Gut of Pigs (1997)

Physico-chemical properties and the digestibility of carbohydrates (starch, β-glucan and arabinoxylan (AX)) were studied in the gastrointestinal contents of pigs fed diets based on oat bran. One diet was made of commercially prepared oat bran and another of oat bran milled to pass a 1 mm screen. The pigs were slaughtered and samples were collected quantitatively from 10 sites of the gastrointestinal tract either 1 or 3 h after the morning feeding. The viscosity of the liquid phase (obtained by centrifugation) of the stomach and small intestinal contents varied greatly between animals, and was not significantly different between segments of the upper gastrointestinal tract. The molecular weight of β-glucan was reduced up to 20-fold in the upper gastrointestinal tract but was of a relatively low digestibility until the terminal ileum. The solubility (the fraction of the total content in the liquid phase of digesta after centrifugation) of β-glucan varied from 0·25 to 0·58 in the stomach and small intestine, whereas the solubility of AX was in the range of 0·04–0·16. Microscopic examination of digesta showed that β-glucan was retained in intact endospermic cell wall structures, which remained evident until the distal small intestine but was completely disrupted in the caecum. In spite of a cumulative digestibility of non-starch polysaccharides and AX of ∽0·90 in the large intestine, identifiable fragments of aleurone cell walls resistant to complete microbial degradation remained. © 1997 SCI.
Buprenorphine as premedication and as analgesic during and after light isoflurane‐N2<sub>O</sub>‐O<sub>2</sub> anaesthesia. A comparison with oxycodone plus fentanyl (1987)

Sixty patients undergoing gynaecological laparotomies under isoflurane anaesthesia received 0.4 mg of buprenorphine sublingually or 0.12 mg/kg of oxycodone intramuscularly in random order for preanaesthetic medication. Patients premedicated with buprenorphine were given buprenorphine before, during and after anaesthesia and patients premedicated with oxycodone received fentanyl before and during anaesthesia and oxycodone after anaesthesia. Buprenorphine premedication produced less drowsiness and sedation and alleviated patients' apprehension significantly (P less than 0.05) less than oxycodone. Systolic and diastolic blood pressure and heart rate were significantly (P less than 0.05 to P less than 0.01) higher after intubation in the buprenorphine group when compared with the oxycodone plus fentanyl group. After anaesthesia, spontaneous respiration started rapidly; the return of consciousness and immediate recovery occurred at the same rate in both groups. In the recovery room moderate to severe pain was more common (P less than 0.05) in the oxycodone plus fentanyl group than in the buprenorphine group. The respiratory rate in the recovery room was lower among patients given buprenorphine, and two patients given buprenorphine developed severe respiratory depression. In the ward (2 to 24 h after operation) sublingual buprenorphine provided pain relief as good as intramuscularly administered oxycodone. No differences were noted in the incidence or severity of emetic symptoms between the groups. It is concluded that buprenorphine can provide good postoperative pain relief for gynaecological laparotomies performed under light isoflurane anaesthesia, but patients need to be monitored carefully after operation because of the possibility of respiratory depression.
Science Achievement and Educational Productivity: A Hierarchical Linear Model (1996)

Abstract Achievement test scores were analyzed in relation to individual- and school-level factors in a national sample of about 2,000 tenth-grade students participating in the Longitudinal Study of American Youth in order to investigate the relative importance of school and individual factors in the determination of science learning. Hierarchical linear analyses showed that individual measures accounted for most of the variance. Previous achievement was the preponderant influence on subsequent achievement. Nonetheless, initial science attitude, instructional time, home environment, and exposure to mass media were also significant individual-level influences on science achievement.
Selecting Conversion Phosphors for White Light-Emitting Diodes (2011)

Light emitting diodes (LEDs) are on the verge of a breakthrough in general lighting, due to their rapidly improving efficiency. Currently, white LEDs with high color rendering are mainly based on wavelength conversion by one or more phosphor materials. This Review first describes how to quantify the quality of a light source, discussing the color rendering index (CRI) and alternative color quality indices. Then, six main criteria are identified and discussed, which should be fulfilled by a phosphor candidate to be considered for actual application in LEDs. These criteria deal with the shape and position of the emission and the excitation spectra, the thermal quenching behavior, the quantum efficiency, the chemical and thermal stability and finally with the occurrence of saturation effects. Based on these criteria, the most common dopant ions (broad-band emitting Eu 2+ , Ce 3+ and Mn 2+ , lineemitting rare earth ions,...) and host compounds (garnets, sulfides, (oxy)nitrides,...
<i>Prince Edward Island and Confederation, 1863-1873</i> (1965)

Find information about UTP Journals. University of Toronto Press is Canada’s leading academic publisher and one of the largest university presses in North America, with particular strengths in the social sciences, humanities, and business. The Book Publishing Division is widely recognized in Canada for its strength in history, political science, sociology, Indigenous studies, and cultural studies. Internationally, UTP is a leading publisher of medieval, Renaissance, Italian, Iberian, Slavic, and urban studies, as well as studies in book and print culture.
Using inertial sensors of iPhone 4 for car navigation (2012)

Smart phones start to equip with MEMS tri-axis accelerometer (i.e. G-sensor) and tri-axis gyroscope chips in recent years for user interface (UI) and game playing purposes. These two sensors actually compose a complete IMU and might be qualified as an INS to aid the GPS positioning of the phones, i.e. a GPS/INS integrated navigation system can be implemented. This paper explores the idea of using the inertial sensors in iPhone 4 from Apple Inc. to make GPS/INS integration for car navigation. A loosely-coupled integrated navigation algorithm with 15-states Kalman filter was used to fuse the data from the GPS and the MEMS inertial sensors. The results of road tests have shown that the MEMS sensors can bridge the GPS position gaps effectively, and can provide attitude estimation at degree level accuracy. The non-holonomic constraint can improve the navigation performance significantly, including both the position and heading. The attitude accuracy can reach the level of 1.4 degrees for tilt, and 2.0 degrees for heading. During the GPS signal outages (e.g. tunnel cases), the position drifts of the MEMS INS are at the level of 30 meters after 30 seconds, with the non-holonomic constraint. Results of this paper proved that the inertial sensors of iPhone 4 can be used for car navigation purpose. They can provide enhanced positioning capability and decent attitude estimation for various applications.