gebhart/patrepeval huggingface dataset:
Reconfigurable media processing (2002)

Multimedia processing is becoming increasingly important with a range of applications. Existing approaches for processing multimedia data can be broadly classified into two categories, namely: (i) microprocessors with extended media processing capabilities; and (ii) dedicated implementations (ASICs). The complexity, variety of techniques and tools associated with multimedia processing points to the opportunities for reconfigurable computing devices which will be able to adapt the underlying hardware dynamically in response to changes in the input data or processing environment. The paper proposes a novel approach to design a dynamically reconfigurable processor by performing hardware software co-design for a media processing application. As an example, the analysis of the shape coding module of MPEG-4 is chosen to demonstrate the potential for reconfigurability.
New and improved (2014)

Existing recommender systems usually model items as static -- unchanging in attributes, description, and features. However, in domains such as mobile apps, a version update may provide substantial changes to an app as updates, reflected by an increment in its version number, may attract a consumer's interest for a previously unappealing version. Version descriptions constitute an important recommendation evidence source as well as a basis for understanding the rationale for a recommendation. We present a novel framework that incorporates features distilled from version descriptions into app recommendation. We use a semi-supervised topic model to construct a representation of an app's version as a set of latent topics from version metadata and textual descriptions. We then discriminate the topics based on genre information and weight them on a per-user basis to generate a version-sensitive ranked list of apps for a target user. Incorporating our version features with state-of-the-art individual and hybrid recommendation techniques significantly improves recommendation quality. An important advantage of our method is that it targets particular versions of apps, allowing previously disfavored apps to be recommended when user-relevant features are added.
Policy-independent real-time operating system mechanisms for timing error detection, handling and monitoring (2002)

Most research focusing on timing errors deals with scheduling policies that avoid the errors. Since many of the policies are based on estimated worst case execution times for each task, reliability is a function of the accuracy of the estimates. As a result, many hard real time systems are implemented with the dangerous assumption that due to correct design and testing, a missed deadline will never occur. We have designed novel policy independent mechanisms for detecting and handling timing errors, and for monitoring real time tasks. The detection and handling requires less than 1 microsecond overhead per reschedule operation, and has a latency approximately the length of one context switch for handling an error. The monitoring mechanism uses 6 microsecond per context switch, and requires only 1 Kbyte of memory per 32 processes in the system.
Sequence Synopsis: Optimize Visual Summary of Temporal Event Data (2017)

Event sequences analysis plays an important role in many application domains such as customer behavior analysis, electronic health record analysis and vehicle fault diagnosis. Real-world event sequence data is often noisy and complex with high event cardinality, making it a challenging task to construct concise yet comprehensive overviews for such data. In this paper, we propose a novel visualization technique based on the minimum description length (MDL) principle to construct a coarse-level overview of event sequence data while balancing the information loss in it. The method addresses a fundamental trade-off in visualization design: reducing visual clutter vs. increasing the information content in a visualization. The method enables simultaneous sequence clustering and pattern extraction and is highly tolerant to noises such as missing or additional events in the data. Based on this approach we propose a visual analytics framework with multiple levels-of-detail to facilitate interactive data exploration. We demonstrate the usability and effectiveness of our approach through case studies with two real-world datasets. One dataset showcases a new application domain for event sequence visualization, i.e., fault development path analysis in vehicles for predictive maintenance. We also discuss the strengths and limitations of the proposed method based on user feedback.
Amelanotic acral melanoma masquerading as fibrous histiocytic tumours. Three case reports. (1993)

We report 3 cases of amelanotic melanoma developing on the finger, whose histology disclosed dermal invasion of histiocyte-like tumour cells. One of the 3 cases was subungual melanoma and the other 2 were on the volar surface of the finger tip. Because of the characteristic dense infiltration of large histiocyte-like tumour cells, including many multinucleated giant cells, we initially considered histiocytic tumours. However, there were some histiocyte-like cells that displayed inclusion-like intranuclear invagination of cytoplasm, and almost all tumour cells, including the giant cells, were positive for S-100 protein. In addition, ultrastructural demonstration of premelanosomes within the cytoplasm of the tumour cells established the diagnosis of amelanotic melanoma. These features were distinct histologically from other variants of vertical growth phase amelanotic malignant melanoma, including desmoplastic or neurotropic melanoma. Because we encountered cases 2 and 3 within just a year after the first case, we think that the misdiagnosis of amelanotic "histiocytic" melanoma can be avoided through enhanced clinical awareness and subsequent appropriate histopathologic studies.
Samuelson PRO and Con (2007)

Fifty three years ago I would not have expected to be able to meet and talk with two presidents Jimmy Carter and George Bush, in 2002; neither would I have expected to be asked to write for Paul Samuelson's 90th. But August 2005 was the 53rd anniversary of my arrival in Cambridge Mass. I applied and was accepted at MIT and at Harvard (also Carnegie, Stanford and Chicago), but Harvard offered a better fellowship net of tuition than MIT or the others, and in the previous May my wife had given birth to twins so I had to deal with economic survival, get my degree and get out of Cambridge; Paul's wife Marion had triplets, showing that Paul was more prolific on all fronts than was I. Just after my arrival in Cambridge, I remember encountering him by accident in a supermarket out on Route 2, and we exchanged stories on the joys for us as fathers of multiple births; the wives were not there.
Controlling the Metal to Semiconductor Transition of MoS<sub>2</sub> and WS<sub>2</sub> in Solution (2015)

Lithiation-exfoliation produces single to few-layered MoS2 and WS2 sheets dispersible in water. However, the process transforms them from the pristine semiconducting 2H phase to a distorted metallic phase. Recovery of the semiconducting properties typically involves heating of the chemically exfoliated sheets at elevated temperatures. Therefore, it has been largely limited to sheets deposited on solid substrates. Here, we report the dispersion of chemically exfoliated MoS2 sheets in high boiling point organic solvents enabled by surface functionalization and the controllable recovery of their semiconducting properties directly in solution. This process connects the scalability of chemical exfoliation with the simplicity of solution processing, ultimately enabling a facile method for tuning the metal to semiconductor transitions of MoS2 and WS2 within a liquid medium.
Simulation Science and Technology in China (2010)

This article provides an overview of the current status of simulation science and technology (SS&T) in China. We briefly examine research and development activities in simulation modeling theory and methodology, simulation systems and technology, and simulation applications. Various facets of the education and training of modeling and simulation professionals in China are also reviewed. Future prospects for modeling and simulation in China are also examined.
Cyclic AMP-dependent Protein Kinase and Protein Kinase C Phosphorylate N-Methyl-d-aspartate Receptors at Different Sites (1997)

Ca2+ influx through N-methyl-D-aspartate (NMDA)-type glutamate receptors plays a pivotal role in synaptic plasticity during brain development as well as in mature brain. Cyclic AMP-dependent protein kinase (PKA) and members of the protein kinase C (PKC) family are also essential for various forms of synaptic plasticity and regulate the activity of different ion channels including NMDA and non-NMDA receptors. We now demonstrate that PKA and various PKC isoforms phosphorylate the NMDA receptor in vitro. The stoichiometry of [32P]phosphate incorporation per [3H]MK-801 binding site is greater than 1 for both PKA and PKC. Double immunoprecipitation experiments show that all three NMDA receptor subunits that are prevalent in the cortical structures, NR1, NR2A, and NR2B, are substrates for PKA as well as PKC. Two-dimensional phosphopeptide mapping reveals that the major phosphorylation sites for PKA and PKC differ for all three subunits. We provide evidence that some if not most of these sites are phosphorylated in the central nervous system of rats in vivo. The results presented in this article together with earlier electrophysiological experiments demonstrating that PKA and PKC activation increases the activity of NMDA receptors indicate that NMDA receptor potentiation can be mediated by direct phosphorylation by PKA and PKC. Collectively, these results strongly suggest that NMDA receptor functions such as control of neuronal development or expression of synaptic plasticity are modulated by PKA- and PKC-mediated phosphorylation of NMDA receptors.
Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4. (1983)

5-Lipoxygenase pathway-derived products of arachidonic acid released by human eosinophils activated in vitro have been measured by using radioimmunoassays specific for leukotriene B4 (LTB4) and for sulfidopeptide leukotrienes including leukotriene C4 (LTC4). Eosinophil-enriched leukocytes (mean, 85% eosinophils) from five hypereosinophilic donors activated with 5.0 microM ionophore A23187 for 15 min at 37 degrees C in the presence of 50 mM L-serine released 69 +/- 28 and 1.5 +/- 0.8 (mean +/- SEM) ng of LTC4 and LTB4, respectively, per 10(6) cells; ratios of LTC4 to LTB4 ranged from 16 to 149. Eosinophils stimulated with ionophore (2.5 microM) or phorbol myristate acetate (1 microgram per ml) metabolized exogenously added LTC4 to products that coeluted on reverse-phase high-performance liquid chromatography with synthetic S-diastereoisomeric LTC4 sulfoxides and 6-trans-LTB4 diastereoisomers, and this metabolic inactivation was inhibited by L-serine or catalase. Ionophore-activated eosinophils purified from three normal donors also preferentially generated LTC4 (38 +/- 3 ng per 10(6) cells) relative to LTB4 (6.0 +/- 3.1 ng per 10(6) cells), whereas neutrophils from the same donors released LTB4 (48 +/- 21 ng per 10(6) cells) in a greater than 7-fold excess to LTC4. The predominant production by human eosinophils of LTC4 with its potent smooth muscle spasmogenic and vasoactive properties may contribute to the pathobiology of allergic and other diseases associated with eosinophilia.
Interactions of tumor cells with vascular endothelial cell monolayers: a model for metastatic invasion. (1979)

The interactions of tumorigenic and nontumorigenic human and rodent cells with vascular endothelial cells and their underlying extracellular matrix were studied in culture. The abilities of various cells to attach to endothelial monolayers and cause morphologic changes, such as rupture of endothelial-endothelial cell interactions leading to retraction of endothelial cells and exposure of extracellular matrix, as well as their propensities to invade and underlap retracted endothelial monolayers and continue migration were assessed by time-lapse and phase-contrast microscopy as well as scanning and transmission electron microscopy. In general, highly malignant or highly invasive cells in vivo were capable of attachment, invasion, and migration under endothelial cells in vitro. This system may be useful for elucidating mechanisms of tumor cell arrest and extravasation.
The<i>BLADE-ON-PETIOLE 1</i>gene controls leaf pattern formation through the modulation of meristematic activity in<i>Arabidopsis</i> (2002)

The plant leaf provides an ideal system to study the mechanisms of organ formation and morphogenesis. The key factors that control leaf morphogenesis include the timing, location and extent of meristematic activity during cell division and differentiation. We identified an Arabidopsis mutant in which the regulation of meristematic activities in leaves was aberrant. The recessive mutant allele blade-on-petiole1-1 (bop1-1) produced ectopic, lobed blades along the adaxial side of petioles of the cotyledon and rosette leaves. The ectopic organ, which has some of the characteristics of rosette leaf blades with formation of trichomes in a dorsoventrally dependent manner, was generated by prolonged and clustered cell division in the mutant petioles. Ectopic, lobed blades were also formed on the proximal part of cauline leaves that lacked a petiole. Thus, BOP1 regulates the meristematic activity of leaf cells in a proximodistally dependent manner. Manifestation of the phenotypes in the mutant leaves was dependent on the leaf position. Thus, BOP1 controls leaf morphogenesis through control of the ectopic meristematic activity but within the context of the leaf proximodistality, dorsoventrality and heteroblasty. BOP1 appears to regulate meristematic activity in organs other than leaves, since the mutation also causes some ectopic outgrowths on stem surfaces and at the base of floral organs. Three class I knox genes, i.e., KNAT1, KNAT2 and KNAT6, were expressed aberrantly in the leaves of the bop1-1 mutant. Furthermore, the bop1-1 mutation showed some synergistic effect in double mutants with as1-1 or as2-2 mutation that is known to be defective in the regulation of meristematic activity and class I knox gene expression in leaves. The bop1-1 mutation also showed a synergistic effect with the stm-1 mutation, a strong mutant allele of a class I knox gene, STM. We, thus, suggest that BOP1 promotes or maintains a developmentally determinate state in leaf cells through the regulation of class I knox genes.
Utilizing Geometric Anomalies of High Dimension: When Complexity Makes Computation Easier (1997)

Just as a busy kitchen can be more efficient than an idle one, Kleinrock showed 35 years ago that heavily used networks admit simple heuristic approximations with excellent quantitative accuracy. We describe a number of different examples in which having many parameters actually facilitates computation and we suggest connections with geometric phenomena in high-dimensional spaces. It seems that in several interesting and quite general situations, dimensionality may be a blessing in disguise provided that some suitable form of computing is used which can deal with it.
Fabrication and Characterization of Smooth Si Mold for Hot Embossing Process (2007)

In this paper, we propose a fabrication and characterization of silicon mold for PMMA hot embossing process. Silicon molds were fabricated from silicon wafer with thickness of 500μm. First, DRIE technique was performed after optimized etching time and deposition (passivation) time to obtain a depth of 30μm with positive tapered sidewall of 1°. This is very important for de-molding process while hot embossing. Second, in order to reduce scalloping steps on the sidewall after DRIE, silicon molds were soaked in the TMAH solution 20% at 80°C for 10 minutes without magnetic stirrer. Third, to further reduce the friction coefficient between sidewall surface and PMMA substrate while de-molding, the post-passivation technique was applied to create a thin layer of Teflon-like material on the surface of the sidewall of silicon mold. These smooth silicon molds were used to emboss several models of PMMA patterns and comb-drive actuators, as well as applications in Micro Conveyer System. The PMMA patterns obtained after hot embossing process had very sharp edge and aspect ratio of 15 with minimum feature sized of 2μm.
Solubility of Structurally Complicated Materials: I. Wood (2005)

Wood is a complex and nonuniform material. Its overall solubility is a combination of the individual components’ ability to come into contact with the specified solvent (e.g., acetone) or blend. The components extracted from wood with a specified solvent represent the solubility of wood in that solvent at the condition described. Some wood compounds are soluble in water and organic solvents but the integral part of the cellular structure cannot be removed by common solvents at ambient temperature. High severities are needed for increased solubility/liquefaction due to temperature, time, and catalytic effects.
Structures of polymer field-effect transistor: Experimental and numerical analyses (2002)

We compare two basic organic field-effect transistor structures both experimentally and theoretically. By using time-resolved analysis, we gain insight into the mechanisms affecting the performance of these structures. Using a two-dimensional numerical model, we focus on the top contact structure and analyze the difference between the two structures.
Ontology-Driven Business Rule Specification (2013)

ABSTRACT Discovering business rules is a complex task for which many approaches have been proposed including analysis, extraction from code, and data mining. In this paper, a novel approach is presented in which business rules for an enterprise model are generated based on the semantics of a domain ontology. Starting from an enterprise model for which the business rules need to be defined, the approach consists of four steps: (1) classification of the enterprise model in terms of the domain ontology (semantic annotation), (2) matching of the enterprise model constructs with ontology-based Enterprise Model Configurations (EMCs), (3) determination of Business Rule Patterns (BRPs) associated with the EMCs, and (4) use of the semantic annotations to instantiate the business rule patterns; that is, to specify the actual business rules. The success of this approach depends on two factors: (1) the existence of a semantically rich domain ontology, and (2) the strength of the knowledge base consisting of EMC-BRP associations. The focus of this paper is on defining and illustrating the new business rule discovery approach: Ontology-Driven Business Rule Specification (ODBRS). The domain of interest is enterprise systems, and an extended version of the Resource-Event-Agent Enterprise Ontology (REA-EO) is used as the domain ontology. A small set of EMC-BRP associations—i.e., an example knowledge base—is developed for illustration purposes. The new approach is demonstrated with an example.
Histological Findings After Transmyocardial Laser Revascularization (1996)

In recent time, it has become more and more probable that patients with severe diffuse coronary artery disease, who are not candidates for aortocoronary bypass surgery or percutaneous transluminal coronary angioplasty procedures, can benefit from transmyocardial laser revascularization (TMR). But the underlying principle of TMR still remains unclear. This study reports on a histological analysis of eight patients, in whom a total of 250 channels had been created, who died after TMR. The TMR channels were created by a CO2 laser surrounded by a zone of necrosis with an extent of about 500 microns. In the hearts of patients who died in the early postoperative period (1 to 7 days postoperative), almost all channels were closed by fibrin clots, erythrocytes, and macrophages. There were no obvious connections between the channels and the ventricular cavity. In specimens from patients, who died 2 or more weeks after the procedure, a granular tissue with high macrophage and monocyte activity was observable. Within this tissue, we observed a developing network of capillaries. Otherwise, the tissue filling the channels did not substantially differ from scar tissue. We failed to observe connections between the ventricular cavity and the new capillaries. Whether these vessels within the closed channels have any impact on myocardial perfusion remains unclear, but it seems unlikely that the clinical effects of TMR are based on the principle of the amphibian heart.
Effects of Difloxacin on the Metabolism of Glycosaminoglycans and Collagen in Organ Cultures of Articular Cartilage (1993)

Fluoroquinolones, including difloxacin, are potent antibacterial compounds which, as a side effect, cause lesions in articular-epiphyseal cartilage complexes (AECC) of growing animals. To evaluate the effects of difloxacin on the structure of AECC and the metabolism of sulfated glycosaminoglycans (GAG) and collagen, explants of AECC were obtained from 18 healthy, 3-month-old Beagle dogs and cultured in medium which either had no difloxacin or had the drug at one of three concentrations (40, 80, or 160 μg/ml). Rates of synthesis of GAG and collagen were reduced by concentrations of difloxacin that were at or above 80 μg/ml. The rate of synthesis of total protein, however, was reduced only at the highest dose level. Catabolism of GAG and collagen was unaffected by the treatment. The principal ultrastructural changes in affected chondrocytes were distension of rough endoplasmic reticulum with electron-dense material that was probably protein, and vacuolation of cytoplasm. Structural changes were not observed in the extracellular matrix. It, therefore, appeared plausible that difloxacin affected chondrocytes by interfering with secretion of the matrix components, GAG and collagen.
Optimization of thin-film tips for magnetic force microscopy (1994)

We report results of a quantitative investigation of MFM sensitivity vs. tip coating thickness. Etched Si tips on cantilevers 225 /spl mu/m in length were sputter-coated with Co-Cr films of various thicknesses 150 /spl Aring/<t<1500 /spl Aring/. Tip response was measured by scanning a specially-written hard disk with tracks of selected bit reversal densities. Tracking the shift in cantilever resonant frequency caused by the disk stray fields gave a measure of relative sensitivity, and hence tip moment. The main finding is a roughly linear increase in sensitivity (effective moment) up to a critical film thickness near 500 /spl Aring/ beyond which saturation occurs. For 500 /spl Aring/ coatings, sensitivity varies about 15% from tip-to-tip, indicating the degree of uniformity that can be expected from batch fabrication. We estimate the effective tip moment to be about 10/sup -12/ emu, implying that only a small portion of the tip's magnetic volume plays a role.<<ETX>>
A smartcard-based framework for secure document exchange (2002)

The advances information and communications technology, especially the Internet, have created the opportunity to improve the administrative efficiency and service quality in governments of many nations. Official documents in Taiwan are traditionally sent to their corresponding recipients through the postal service. It has not been possible to securely transfer official document via the open network using off-the-shelf e-mail systems. We present our work on integrating smartcard-based security services (confidentiality, authentication, and nonrepudiation) into XML-based document exchange systems.
Attenuation of hyperoxia-induced lung injury in neonatal rats by 1α,25-Dihydroxyvitamin D<sub>3</sub> (2015)

1,25(OH)2D3 could attenuate hyperoxia-induced lung injury in neonatal rats, possibly by regulating TLR4/NF-κB signaling.