gebhart/patrepeval huggingface dataset:
Hydrocarbon Uptake in the Alkylated Micropores of a Columnar Supramolecular Solid (2006)

Neither Doric, Ionic, nor Corinthian! (HgC6F4)3 interacts with 1,3,5-(Me3SiCC)3C6H3 to form columns with peripheral trimethylsilyl groups. These columns self-aggregate into a hexagonal solid containing pores lined by nonpolar methyl groups (see picture; Hg orange, Si purple, C gray, F green, H white), which can adsorb alkanes reversibly. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z602440_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Impact of sediment transport efficiency on large‐scale sequence architecture: results from stratigraphic computer simulation (1997)

Our understanding of the formation of the wide range of sequence architectures we observe in the rock record is still somewhat limited. The sedimentary response to the complex interaction of various time‐variable basin‐scale processes such as subsidence, eustasy and sediment supply is difficult to understand without numerical models. The computer simulation model presented here, DEMOSTRAT, is a powerful tool to investigate the sequence development scenarios in a 2‐D dip section. The model includes tectonic subsidence, eustasy, two‐component (sand and mud) nonlinear diffusional sediment transport, compaction and isostasy. The transport coefficients in the diffusion equations express the system’s ability to transport sand and mud, and are mainly dependent on climate and subaquatic processes. Keeping other model input parameters constant, the magnitude of transport coefficients seems to have an important impact on sequence development. With high transport coefficients, extensive erosion during sea‐level fall and lack of sediment buildup above sea‐level during rise may reduce the preservation potential for nonmarine sediments. In addition, the former slope break will be eroded during transgression, forming sand‐rich slope or basin floor sediments that may be misinterpreted as lowstand fans. Moreover, the magnitude of transport coefficients has an impact on unconformity timing and development (shown in Wheeler plots).
Histological study of an acid red caries-disclosing dye. (1989)

When 20 extracted teeth were examined histologically after using a 1.0% acid red caries-disclosing dye before excavation of carious dentin, 25% showed the presence of bacteria in the dentin. The use of a solution of 1.0% acid red in propylene glycol to identify infected dentin will greatly decrease but not completely eliminate the changes of viable bacteria remaining in a cavity preparation.
The action of ten secreted aspartic proteases of pathogenic yeast Candida albicans on major human salivary antimicrobial peptide, histatin 5 (2016)

Candida albicans, belonging to the most common fungal pathogens of humans, exploits many virulence factors to infect the host, of which the most important is a family of ten secreted aspartic proteases (Saps) that cleave numerous peptides and proteins, often deregulating the host's biochemical homeostasis. It was recently shown that C. albicans cells can inactivate histatin5 (His5), a salivary histidine-rich anticandidal peptide, through the hydrolytic action of Saps. However, the current data on this subject are incomplete as only four out of ten Saps have been studied with respect to hydrolytic processing of His5 (Sap2, Sap5, Sap9-10). The aim of the study was to investigate the action of all Saps on His5 and to characterize this process in terms of peptide chemistry. It was shown that His5 was degraded by seven out of ten Saps (Sap1-4, Sap7-9) over a broad range of pH. The cleavage rate decreased in an order of Sap2>Sap9>Sap3>Sap7>Sap4>Sap1>Sap8. The degradation profiles for Sap2 and Sap9 were similar to those previously reported; however, in contrast to the previous study, Sap10 was shown to be unable to cleave His5. On a long-time scale, the peptide was completely degraded and lost its antimicrobial potential but after a short period of Sap treatment several shorter peptides (His1-13, His1-17, His1-21) that still decreased fungal survival were released. The results, presented hereby, provide extended characteristics of the action of C. albicans extracellular proteases on His5. Our study contribute to deepening the knowledge on the interactions between fungal pathogens and the human host.
The Quality of School Life in the Senior Years (1988)

ABSTRACT The feelings of 305 senior high school students about the quality of their school life were measured by giving them the Quality of School Life inventory at spaced intervals as they progressed through Years 11 and 12. Their self-estimates of school work ability and their reasons for continuing at school were also assessed. A decline was found in the initially positive feelings that were associated with the content of their studies and with their success as students. Separately analysed for comparison were the responses of students who subsequently left school without completing Year 12. Implications are discussed in terms of the drive to improve the retention rate in the post-compulsory years of secondary education, and students' expectations of the demands of the senior curriculum.
Contact Electrification and Energy Harvesting Using Periodically Contacted and Squeezed Water Droplets (2015)

We investigate the contact electrification occurring when a small water droplet resting on a metal electrode is brought periodically in contact with a hydrophobic film of fluorinated ethylene propylene. It is found that the maximum current increases with the drop volume according to a power law. The time scale for the contact current to develop is consistent with that required for a droplet to spread and is, therefore, longer than the time required to form the electric double layer. Adding salt into the water does reduce the contact current but not entirely, which suggests that any remaining water layer cannot entirely neutralize the charges developed upon contact. With an average power of 0.7 μW and a peak power near 5 μW at a frequency of 5 Hz, a 200 μL droplet of pure water can be used to light up a light-emitting diode.
Redox cycling without reference electrodes (2014)

The reference electrode is a key component in electrochemical measurements, yet it remains a challenge to implement a reliable reference electrode in miniaturized electrochemical sensors. Here we explore experimentally and theoretically an alternative approach based on redox cycling which eliminates the reference electrode altogether. We show that shifts in the solution potential caused by the lack of reference can be understood quantitatively, and determine the requirements for accurate measurements in miniaturized systems in the absence of a reference electrode.
N-Methyl-D-aspartate/phencyclidine receptor complex of rat forebrain: purification and biochemical characterization (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN-Methyl-D-aspartate/phencyclidine receptor complex of rat forebrain: purification and biochemical characterizationAnnat F. Ikin, Yoel Kloog, and Mordechai SokolovskyCite this: Biochemistry 1990, 29, 9, 2290–2295Publication Date (Print):March 6, 1990Publication History Published online1 May 2002Published inissue 6 March 1990https://pubs.acs.org/doi/10.1021/bi00461a012https://doi.org/10.1021/bi00461a012research-articleACS PublicationsRequest reuse permissionsArticle Views41Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
OCCURRENCE OF PNEUMOCYSTIS CARINII PNEUMONIA IN CHILDREN WITH AGAMMAGLOBULINEMIA (1961)

Two case histories of patients having apparent congenital agammaglobulinemia who succumbed to Pneumocystis carinii pneumonia are presented. The high incidence of agammaglobulinemia or extreme hypogammaglobulinemia among patients with Pneumocystis pneumonia in Great Britain, Canada and the United States is stressed. The absence or gross deficiency of plasma cells in the pulmonary lesions and in the hematopoietic tissues of the children having agammaglobulinemia and Pneumocystis carinii infection is contrasted to the extensive plasmacytosis occurring in most children succumbing to infection due to this organism. The use of Giemsa staining of imprints from fresh or previously frozen pulmonary tissue as an ideal method for demonstrating the parasite is emphasized.
Inheritance graph assessment using metrics (2002)

Presents a new method integrated in Bell Canada's software acquisition process to assess software. This paper is focused on the assessment of the understandability of the inheritance graph of object-oriented software. The method is based on metrics and on the graphical illustration of the inheritance graph. A technique to decompose the inheritance graph of an object-oriented program into sub-graphs using metrics is described. Metrics are also used to identify complex sub-graphs. On the selected graphs, a technique to improve the understandability of the graphical illustration representing the inheritance graph is also described. This technique is based on extracting the main tree on the inheritance graph. A C++ case study containing 1080 classes is presented, on which this assessment method was applied.
Porous PbI<sub>2</sub>films for the fabrication of efficient, stable perovskite solar cells via sequential deposition (2016)

A new approach is introduced to synthesize porous PbI<sub>2</sub>, which produces a PbI<sub>2</sub>-free, crystallinity enhanced and air-stable MAPbI<sub>3</sub>perovskite film.
A new approach to high-frequency delay lines (1964)

The characteristics of a proposed yttrium-iron-garnet (YIG) delay line with adjustable delay time are presented. Operation would be at GC frequencieasn d at room temperature with delay time controlled by an external magnetic field. The frequency-delay-magnetic field characteristics are discussed. Under ideal conditions, it may be possible to achieve tfhoell owing characteristics, although not simultaneously: 1) conversion loss approximately equal to 0.1 db/conversion, 2) insertion loss approximately equal to 5-10 db/μsec at 3 GC, 3) maximum delay time approximately equal to 10 μsec, 4) magnetic control of delay time over a 5:l range, and 5) fractional bandwidth of 10%.
A Bandwidth Selector for Bivariate Kernel Regression (1995)

SUMMARY For two and higher dimensional kernel regression, currently available bandwidth selection procedures are based on cross-validation or related penalizing ideas. However, these techniques have been shown to suffer from high sample variability and, in addition, can sometimes be difficult to implement when a vector of bandwidths needs to be selected. In this paper we propose a selector based on an iterative plug-in approach for bivariate kernel regression. It is shown to give satisfactory results and can be quickly computed. Our ideas can be extended to higher dimensions.
MxML: Mixture of Meta-Learners for Few-Shot Classification (2019)

A meta-model is trained on a distribution of similar tasks such that it learns an algorithm that can quickly adapt to a novel task with only a handful of labeled examples. Most of current meta-learning methods assume that the meta-training set consists of relevant tasks sampled from a single distribution. In practice, however, a new task is often out of the task distribution, yielding a performance degradation. One way to tackle this problem is to construct an ensemble of meta-learners such that each meta-learner is trained on different task distribution. In this paper we present a method for constructing a mixture of meta-learners (MxML), where mixing parameters are determined by the weight prediction network (WPN) optimized to improve the few-shot classification performance. Experiments on various datasets demonstrate that MxML significantly outperforms state-of-the-art meta-learners, or their naive ensemble in the case of out-of-distribution as well as in-distribution tasks.
CrowdER (2012)

Entity resolution is central to data integration and data cleaning. Algorithmic approaches have been improving in quality, but remain far from perfect. Crowdsourcing platforms offer a more accurate but expensive (and slow) way to bring human insight into the process. Previous work has proposed batching verification tasks for presentation to human workers but even with batching, a human-only approach is infeasible for data sets of even moderate size, due to the large numbers of matches to be tested. Instead, we propose a hybrid human-machine approach in which machines are used to do an initial, coarse pass over all the data, and people are used to verify only the most likely matching pairs. We show that for such a hybrid system, generating the minimum number of verification tasks of a given size is NP-Hard, but we develop a novel two-tiered heuristic approach for creating batched tasks. We describe this method, and present the results of extensive experiments on real data sets using a popular crowdsourcing platform. The experiments show that our hybrid approach achieves both good efficiency and high accuracy compared to machine-only or human-only alternatives.
Computer-aided modeling of controlled release through surface erosion with and without microencapsulation (2007)

Predictive models for diffusion-controlled particle dissolution are important for designing advanced and efficient solid products for controlled release applications. A computer-aided modeling framework was developed to derive the effective dissolution rates of multiple particles as the solid surface material eroded gradually into the surrounding liquid phase. The mathematical models were solved with numerical methods using the computational software MATLAB. Results from the models were imported into COMSOL Script to create three-dimensional plots of the particle size data as a function of time. The release model found for the monodispersed particles was manipulated to incorporate polydisperse solids, as these are found more frequently in chemical processes. The program was further developed to calculate the particle size as a function of time for particles encapsulated for use in controlled release. The parameters, such as radius size, coating material and encapsulation thickness, can be altered in the computer models to aid in the design of particles for different desired applications. Simulations produced conversion profiles and three-dimensional visualizations for the dissolution processes. Experiments for the dissolution of citric acid in water were performed using a reaction microcalorimeter to verify results found from the computer models.
Nanometric lateral scale development with Si/SiO<sub>2</sub>multilayer thin-film structures and improvement of uncertainty evaluation using analysis of variance (2008)

A nanometric lateral scale (design pitch: 25 nm) with Si/SiO2 multilayer thin-film structures was developed. The pitch of the developed nanometric lateral scale was calibrated using an atomic force microscope with a differential laser interferometer, and the uncertainty in pitch measurement was evaluated. In the uncertainty evaluation, two evaluation methods were revised to avoid overestimation. The analysis of variance was applied to the evaluation of uncertainties caused by the nonuniformity of the scale and the repeatability of the measurements in the same location. The expanded uncertainties (k = 2) were 29?154 pm in this study and became smaller than 0.43 nm, which is the expanded uncertainty evaluated in our previous study.
Improved DOP-PCR???Based Representational Whole-Genome Amplification Using Quantitative Real-Time PCR (2006)

In many cases, only a minute amount of partially degraded genomic DNA can be extracted from archived clinical samples. Diverse whole-genome amplification methods are applied to provide sufficient amount of DNA for comparative genome hybridization, single-nucleotide polymorphism, and microsatellite analyses. In these applications, the reliability of the amplification techniques is particularly important. In PCR-based approaches, the plateau effect can seriously alter the original relative copy number of certain chromosomal regions. To eliminate this distorting effect, we improved the standard degenerate oligonucleotide-primed PCR (DOP-PCR) technique by following the amplification status with quantitative real-time PCR (QRT-PCR). With real-time detection of the products, we could eliminate DNA overamplification. Probes were prepared from 10 different tumor samples: primary and metastatic melanoma tissues, epidermoid and bronchioloalveolar lung carcinomas, 2 renal cell carcinomas, 2 colorectal carcinomas, and a Conn and Cushing adenoma. Probes were generated by using nonamplified and amplified genomic DNA with DOP-PCR and DOP-PCR combined with QRT-PCR. To demonstrate the reliability of the QRT-PCR based amplification protocol, altogether 152 relative copy number changes of 44 regions were determined. There was 85.6% concordance in copy number alterations between the QRT-PCR protocol and the nonamplified samples, whereas this value was only 63.8% for the traditional DOP-PCR. Our results demonstrate that our protocol preserves the original copy number of different chromosomal regions in amplified genomic DNA than standard DOP-PCR techniques more accurately.
Nitric oxide represses inhibitory κB kinase through S-nitrosylation (2004)

Nitric oxide (NO) possesses antiinflammatory effects, which may be exerted via its ability to inhibit the transcription factor, NF-kappaB. A commonly proposed mode of action for inhibition of NF-kappaBbyNO involves interference with NF-kappaB binding to DNA. Because activation of inhibitory kappaB kinase (IKK), the prerequisite enzyme complex necessary to induce NF-kappaB, is subject to redox regulation, we assessed whether IKK could present a more proximal target for NO to inhibit NF-kappaB activation. We demonstrate here that S-nitrosothiols (SNO) caused a dose-dependent inhibition of the enzymatic activity of IKK, in lung epithelial cells and in Jurkat T cells, which was associated with S-nitrosylation of the IKK complex. Using biotin derivatization of SNO, we revealed that IKKbeta, the catalytic subunit required for NF-kappaB activation, was a direct target for S-nitrosylation. A mutant version of IKKbeta containing a Cys-179-to-Ala mutation was refractory to inhibition by SNO or to increases in S-nitrosylation, in contrast to wild-type IKKbeta, demonstrating that Cys-179 is the main target for attack by SNO. Importantly, inhibition of NO synthase activity in Jurkat T cells resulted in activation of IKK, in association with its denitrosylation. Moreover, NO synthase inhibition enhanced the ability of tumor necrosis factor alpha to activate IKK, illustrating the importance of endogenous NO in regulating the extent of NF-kappaB activation by cytokines. Collectively, our findings demonstrate that IKKbeta is an important target for the redox regulation of NF-kappaB by endogenous or exogenous NO, providing an additional mechanism for its antiinflammatory properties.
Microporous titanosilicate ETS-10: A structural survey (1995)

Abstract The structure of a microporous titanosilicate, ETS-10, has been solved using a combination of electron microscopy, X-ray and electron diffraction, solid-state NMR and distance-least squares analysis. We describe in detail how these tools have been applied to the structural solution. ETS-10 is a highly disordered, yet crystalline, wide-pore microporous framework material containing octahedrally coordinated titanium and tetrahedrally coordinated silicon. The disordered material can be described with respect to two ordered polymorphs: polymorph A, space group P41 or P43 with a = b = 14·8 Å and α = β = γ = 90° polymorph B, space group C2/c with a = b = 21·00 Å, c= 14·51 Å and α = γ = 90°, β= 111·12°. Both polymorphs have'a three-dimensional 12-ring pore system and polymorph A has a spiral channel.
Joseph of Arimathaea. (1928)

THE account of the death of Jesus in John xix, 31-37 has re- vealed two different versions of how Jesus was buried.The first tells us that he was treated exactly as all other Palestinians that were crucified.That is to say, his legs were crushed and his re- mains thrown into a nearby natural or artificial cave whose entrance was closed with a stone.That agreed with the Mosaic law and satisfied the Jews.But in verse 33 ff., Jesus is handled differently.His legs are not broken.Only his side is pierced to make sure of his death.P.ut the spear is driven into his heart so carefully that not a single rib was broken.The strange behavior of the Roman soldiers is explained in verse 35-37.They had to fulfil two Old Testament predictions which told what was to happen to the body of the Messiah after his death.L'n fortunately the Old Testament does not contain such prophecies.THE OPEN COURT thorough Roman education, was familiar with the Roman law, and could act as diplomatic middleman between the high priest and the governor.Clearly, only a Jew born, raised, and educated at Rome, could fill that important position.The one mentioned Acts xxiv, 1 called himself Tertullus.If the orator's name when Jesus was crucified, was Joseph, his full name must have been Joseph of Rome, not of Arimathaea.The Syriac noun Arimathaea would not exclude that.For it may mean Rome.But Joseph of Rome would never have placed the corpse of Jesus into any tomb and least of all into another man's tomb.He was present only to watch whether the Roman soldiers satisfied the Jewish law concerning the burial of criminals.
Saposin B binds and transfers phospholipids (2006)

Saposin B (Sap B) is a member of a family of four small glycoproteins, Sap A, B, C, and D. Like the other three saposins, Sap B plays a physiological role in the lysosomal degradation of sphingolipids (SLs). Although the interaction of Sap B with SLs has been investigated extensively, that with the main membrane lipid components, namely phospholipids and cholesterol (Chol), is scarcely known. Using large unilamellar vesicles (LUVs) as membrane models, we have now found that Sap B simultaneously extracts from the lipid surface neutral [phosphatidylcholine (PC)] and anionic [phosphatidylinositol (PI)] phospholipids, fewer SLs [ganglioside GM1 (GM1) or cerebroside sulfate (CS)], and no Chol. More PI than SL (GM1 or CS) was solubilized from LUVs containing equal amounts of PI and SLs. An increase in PI level had a poor effect on the Sap B-induced solubilization of GM1 or CS but strongly inhibited that of PC. Sap B was able not only to bind, but also to transfer phospholipids between lipid surfaces. Both the phospholipid binding and transfer activities were optimal at low pH values. These results represent the first biochemical analysis of the Sap B interaction with phospholipids. The capacity of Sap B to bind and transfer phospholipids occurs under conditions mimicking the interior of the late endosomal/lysosomal compartment and thus might have physiological relevance.