gebhart/patrepeval huggingface dataset:
The impact of perceived social support, loneliness, and physical activity on quality of life in South Korean older adults (2016)

The SEM results of the current study support the proposed model that explained the interrelationships among perceived social support, loneliness, PA, and QoL among active older adults in South Korea. These findings suggest the importance of incorporating social support mechanisms for PA interventions in order to enhance QoL. The findings of this study can help create more effective health and physical education programs for the older generations in South Korea to enhance their QoL.
NYMPH: A multiprocessor for manipulation applications (1986)

The robotics group of the Stanford Artificial Intelligence Laboratory is currently developing a new computational system for robotics applications. Stanford's NYMPH system uses multiple NSC 32016 processors and one MC68010 based processor, sharing a common Intel Multibus. The 32K processors provide the raw computational power needed for advanced robotics applications, and the 68K provides a pleasant interface with the rest of the world. Software has been developed to provide useful communications and synchronization primitives, without consuming excessive processor resources or bus bandwidth. NYMPH provides both large amounts of computing power and a good programming environment, making it an effective research tool.
Abundance and Diversity of Dockerin-Containing Proteins in the Fiber-Degrading Rumen Bacterium, Ruminococcus flavefaciens FD-1 (2010)

This report profiles the abundance and sequence diversity of the R. flavefaciens FD-1 dockerins, and provides the molecular basis for future understanding of the potential for a wide array of cohesin-dockerin specificities. Conserved differences between dockerins may be reflected in their stability, function or expression within the context of the parent protein, in response to their role in the rumen environment.
Gating Current Noise Produced by Elementary Transitions in <i>Shaker</i> Potassium Channels (1994)

Gating currents provide a direct record of the spatial rearrangement of charges occurring within the protein of voltage-sensitive ion channels. If the elementary charges move as very brief discrete pulses of current, they will produce fluctuations in the macroscopic gating current. The variance of such fluctuations in gating currents was measured in Shaker potassium channels expressed in Xenopus oocytes with a sufficiently high recording bandwidth to estimate the magnitude and time distribution of the elementary transition charge movements. Channel activation occurred in two sequential stages. The first stage consisted of numerous, fast transitions, each moving small amounts of charge that contributed little to the fluctuation in gating current, whereas the second stage, which contributed the bulk of the fluctuation, was represented by a number of discrete, correlated transitions, one or more of which carried a charge of at least 2.4 elementary charges across the membrane field.
Electrooptic Behaviour of Proton Exchanged LiNbO3 Optical Waveguides (1988)

Par utilisation d'un prisme electrooptique et d'interferometres a couches guidantes, on calcule le coefficient electrooptique d'un guide d'onde en metaniobate de lithium a partir de la deflexion d'un faisceau gaussien lateral et de la mesure du decalage de phase, cause par l'application d'un champ electrique externe sur la structure
Word sense disambiguation with specification marks in unrestricted texts (2002)

The authors present a method for the automatic disambiguating of nouns in English texts, using the notion of specification marks and employing the noun taxonomy of the WordNet lexical knowledge base (G.A. Miller et al., 1990). The method resolves the lexical ambiguity of nouns in any sort of text, and although it relies on the semantic relations (Hypernymy and Hyponymy) and the hierarchic organization of WordNet, it does not, however, require any sort of training process, no hand-coding of lexical entries, nor the hand-tagging of texts. An evaluation of the method was done on both the Semantic Concordance Corpus (Semcor) (G.A. Miller et al., 1993), and on Microsoft's electronic encyclopaedia ("Microsoft 98 Encarta Encyclopaedia Deluxe"). The percentage of correct resolutions achieved with these two corpora were: Semcor 65.8% and Microsoft 65.6%. Such results suggest that our proposed method is quite a stable one.
CAR-NK for tumor immunotherapy: Clinical transformation and future prospects (2019)

Recently, the use of chimeric antigen receptor-modified T (CAR-T)-cells in the treatment of hematological tumors has been successful and has become a clinical hotspot in tumor immunotherapy. However, their wide application is limited by inherent risks such as graft-versus-host disease (GvHD) and the amount of time it takes to produce CAR-T cells. Natural killer (NK) cells can be xenografted and have the potential to become off-the-shelf products, making CAR-NK cell therapies universal products. These products may be safer than CAR-T cell therapy. Considering that the fundamental researche is still in its infancy, this review focuses on clinical achievements and new strategies for improving the safety and efficacy of CAR-NK cell therapy, as well as the corresponding challenges.
Research on interoperation access control based on OBAC and dynamic trust management (2010)

The access control mechanism is the one key issue in realizing safety interoperation between distributed information systems. However, the existing multi-domains interoperation access control based on RBAC can not satisfy the safety needs of information system interoperability, in which the sort of users and information are diverse and update frequently. Therefore, the interoperation access control model-DTM-OBAC, based on OBAC and dynamic trust management, was studied in this paper, as to provide a dynamic safety mechanism for information system interoperability across domains.
Design of haptic interfaces for therapy (2009)

Touch is fundamental to our emotional well-being. Medical science is starting to understand and develop touch-based therapies for autism spectrum, mood, anxiety and borderline disorders. Based on the most promising touch therapy protocols, we are presenting the first devices that simulate touch through haptic devices to bring relief and assist clinical therapy for mental health. We present several haptic systems that enable medical professionals to facilitate the collaboration between patients and doctors and potentially pave the way for a new form of non-invasive treatment that could be adapted from use in care-giving facilities to public use. We developed these prototypes working closely with a team of mental health professionals.
A Stochastic Model to Assess the Variability of Blood Glucose Time Series in Diabetic Patients Self-Monitoring (2006)

Several studies have shown that patients suffering from Diabetes Mellitus can significantly delay the onset and slow down the progression of diabetes micro- and macro-angiopathic complications through intensive monitoring and treatment. In general, intensive treatments imply a careful blood glucose level (BGL) self-monitoring. The analysis of BGL measurements is one of the most important tasks in order to assess the glucose metabolic control and to revise the therapeutic protocol. Recent clinical studies have shown the correlation between the glucose variability and the long-term diabetes related complications. In this paper, we propose a stochastic model to extract the time course of such variability from the self-monitoring BGL time series. This information can be conveniently combined with other analysis to evaluate the adequacy of the therapeutic protocol and to highlight periods characterized by an increasing glucose instability. The method here proposed has been validated on two simulated data sets and tested with success in the retrospective analysis of three patients' data sets.
Indirect energy gap of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">C</mml:mi></mml:mrow><mml:mprescripts/><mml:mrow/><mml:mrow><mml:mn>13</mml:mn></mml:mrow><mml:mrow/><mml:mrow/></mml:mmultiscripts></mml:mrow></mml:math>diamond (1990)

Optical-absorption and luminescence measurements on $^{13}\mathrm{C}$ and $^{12}\mathrm{C}$ diamonds establish that the indirect energy gap is 13.6\ifmmode\pm\else\textpm\fi{}0.2 meV higher for $^{13}\mathrm{C}$ than for $^{12}\mathrm{C}$ diamond. Zero-parameter calculations, allowing for the changes in electron-phonon coupling and lattice parameter, give an estimated shift of 16.5\ifmmode\pm\else\textpm\fi{}2.5 meV.
Al-doped zinc oxide films deposited by simultaneous rf and dc excitation of a magnetron plasma: Relationships between plasma parameters and structural and electrical film properties (1998)

A new technique of the simultaneous excitation of a magnetron sputtering discharge by rf and dc was used for the deposition of undoped ZnO- and Al-doped ZnO (ZnO:Al) films. By this technique, it was possible to change the ion-to-neutral ratio ji/jn on the substrates during the film growth by more than a factor of ten, which was revealed by plasma monitor and Langmuir probe measurements. While for a pure dc discharge the ions impinging onto a floating substrate have energies of about Ei≈17 eV, the rf discharge is characterized by Ar-ion energies of about 35 eV. Furthermore, the ion current density for the rf excitation is higher by a factor of about five, which is caused by the higher plasma density in front of the substrate. This leads to a much higher ion-to-neutral ratio ji/jn on the growing film in the case of the rf discharge, which strongly influences the structural and electrical properties of the ZnO(:Al) films. The rf-grown films exhibit about the three times lower specific resistances (ρ≈6×10−4 Ω cm), due to lower mechanical stress, leading to higher charge carrier concentrations and mobilities. Undoped ZnO films exhibited the largest compressive stress values up to 2.8 GPa. The aluminium-doped films have a better (001) texture and larger grains (dg≈38 nm), which can be attributed to the beneficial role of Al as a surfactant. The better crystalline film quality of the ZnO:Al films is the reason for the much lower compressive stress of &lt;0.5 GPa in these layers.
Leveraging traditional EDI investment using the Internet: a case study (2003)

For many large retail companies with many suppliers, the utopian vision of total paperless trading offered by traditional electronic data interchange (EDI), with its attendant efficiencies, has not been realized. Many small but operationally important suppliers lack enthusiasm for traditional EDI because it is expensive, complicated and they stand to gain little from it. This non-compliance prevents the large organization from realizing some of the most significant tactical benefits of EDI such as advanced supply chain reforms. This paper presents a case study of a large retail organization which is approaching this problem by integrating Internet-based EDI with its existing traditional EDI systems using an intelligent gateway. The case study is used to generate propositions about the future significance of Internet EDI.
EUV Lithography System with Diffraction Optics (2019)

A maskless, extreme ultraviolet (EUV) lithography scanner uses an array of microlenses, such as binary-optic, zone-plate lenses, to focus EUV radiation onto an array of focus spots (e.g. about 2 million spots), which are imaged through projection optics (e.g., two EUV mirrors) onto a writing surface (e.g., at 6X reduction, numerical aperture 0.55). The surface is scanned while the spots are modulated to form a high-resolution, digitally synthesized exposure image. The projection system includes a diffractive mirror, which operates in combination with the microlenses to achieve point imaging performance substantially free of geometric and chromatic aberration. Similarly, a holographic EUV lithography stepper can use a diffractive photomask in conjunction with a diffractive projection mirror to achieve substantially aberration-free, full-field imaging performance for high-throughput, mask-projection lithography. Maskless and holographic EUV lithography can both be implemented at the industry-standard 13.5-nm wavelength, and could potentially be adapted for operation at a 6.7-nm wavelength.
Antitumor activity of flavonoids on NK/Ly ascites tumor cells. (1981)

Among the various flavonoids, rutin and quercetin increased the survival time of mice inoculated with NK/Ly ascites tumor cells. The best results were obtained when the mice were given 2.0 mg rutin twice daily for 8 days. The O-silyl-substituted rutin and quercetin were less effective than rutin or quercetin themselves. Besides rutin, quercetin and morin two other flavonoids, luteolin and pelargonidin also exerted growth inhibitory effects on NK/Ly ascites tumor cells cultures in vitro.
Environmental-Stress Tolerant Formulations of Metarhizium anisopliae var. acridum for Control of African Desert Locust (Schistocerca gregaria) (2001)

Entomopathogenic fungi are highly susceptible to the damaging effects of solar radiation. Attempts to protect entomopathogenic fungi from solar radiation have been, for the most part, unsuccessful. A new strategy for formulating entomopathogenic fungi for protection from solar radiation and desiccation has been tested using the acridid entomopathogen Metarhizium anisopliae var acridum (IMI 330189). This strategy involves coating spores with water-soluble materials that provide protection from solar radiation and enhance spore survival during drying. Development of this formulation involved the following: 1) production of an infective spore-type in liquid culture that could survive drying; 2) coating spores during an air-drying process; 3) reducing formulation particle size for oil suspension; 4) testing the effects spore coating on sporetolerance simulated sunlight; and 6) testing the effects of spore coating infectivity to Schistocerca americana.
Glomerular Basement Membrane Antigens in Congenital and Acquired Nephrotic Syndrome in Childhood (1976)

Urinary and serum glomerular basement membrane (GBM) antigens were detected by immunodiffusion in patients with nephrotic syndrome and in healthy subjects. The excretion of urinary GBM antigens was greatest in patients with congenital nephrotic syndrome of Finnish type (CNF) and in patients with acquired, therapy-resistant nephrotic syndrome who had a variety of histologically identified glomerular lesions. One GBM antigen, indistinguishable from the urinary one, was also detected in the serum of four of these patients. Excretion of urinary GBM antigens was within normal limits, in patients with steroid-sensitive nephrotic syndrome with minimal changes in renal histology and in the parents (heterozygotes) of CNF patients.
Engine Cooling System with a Heat Load Averaging Capability (2008)

<div class="htmlview paragraph">There is a need for an automotive engine cooling system capable of handling increased heat load while, at the same time, having reduced size and weight. This paper evaluates a concept for an engine cooling system with a passive heat accumulator that averages out peak heat loads. Heat load averaging permits relaxation of the cooling system requirements and allows substantial reduction of system size and weight. This also translates to a smaller coolant inventory allowing for faster engine warm-up and reduced emissions of harmful pollutants during a cold engine start.</div>
Negotiation of Intracellular Membrane Barriers by TAT-Modified Gold Nanoparticles (2011)

This paper contributes to the debate on how nanosized objects negotiate membrane barriers inside biological cells. The uptake of peptide-modified gold nanoparticles by HeLa cells has been quantified using atomic emission spectroscopy. The TAT peptide from the HIV virus was singled out as a particularly effective promoter of cellular uptake. The evolution of the intracellular distribution of TAT-modified gold nanoparticles with time has been studied in detail by TEM and systematic image analysis. An unusual trend of particles disappearing from the cytosol and the nucleus and accumulating massively in vesicular bodies was observed. Subsequent release of the particles, both by membrane rupture and by direct transfer across the membrane boundary, was frequently found. Ultimately, near total clearing of particles from the cells occurred. This work provides support for the hypothesis that cell-penetrating peptides can enable small objects to negotiate membrane barriers also in the absence of dedicated transport mechanisms.
[The sodium-iodide-symporter (NIS): function, regulation and clinical importance]. (1999)

Cloning, functional characterisation, and diagnostic proof of the expression of sodium-iodide-symporter (NIS) in the thyroid are essential steps for a better understanding of function and regulation of thyroid hormone synthesis, which is limited by the availability of the trace element iodide. The physiological or pharmacological modulation of NIS function can now be used for a rational functional diagnosis and therapy of thyroid diseases. Diagnostic procedures based on analysis of the this gene or its expression are already in use for the analysis of benign and malignant alterations of the thyroid. Experimental protocols aiming at the functional expression of NIS in thyroid tumors or their metastases which lost capability for iodide uptake are currently developed. Furthermore, techniques are under investigation to express functional NIS by gene transfer in those benign or malignant tissues, tumors, metastases, which normally do not accumulate iodide. This would allow application of radioiodide therapy, a save and established technique to non-thyroid-related fatal diseases.
Opportunities for doctoral graduates within agricultural industries (2009)

Doctoral graduates regularly choose positions in the private sector following completion of their postgraduate studies. The reasons for doing so are many and varied; a desire to be involved in the commercial application of research, lack of opportunity or disillusionment with the academic research environment, greater prospects for continuing employment, potential for greater financial reward, the opportunity to be involved in a range of activities in addition to research, or opportunities to continue with their own research interests. Preparing for the challenges involved in industry-based research is generally not a core part of graduate research candidature, so deciding to accept a position in industry can be a 'leap into the great unknown'. In this chapter, we examine some ofthe strategies used by doctoral graduates to secure postdoctoral research positions in industry, outline some of the challenges of industry positions and discuss strategies adopted to address these challenges. Information in this chapter is drawn from our experience with the agricultural sector, which covers production agriculture, natural resource management and microbial food safety; however, many of these strategies are relevant to a wide range of employment opportunities within industry.
High resolution map around the <i>vrs1</i> locus controlling two- and six-rowed spike in barley, <i>Hordeum vulgare</i> (1999)

The vrs1 (formerly v) locus in the long arm of chromosome 2H controls lateral spikelet development in barley. The vrs1 locus was mapped by backcross-derived lines that consisted of 373 BC 7 F 1 plants and 278 BC 6 F 2 plants. The linkage study indicated that MWG801, CMNA-38/700, cMWG699, vrs1 and MWG865 exist in the order listed, with map distances of 3.1, 0.4, 0.1, and 0.9 centimorgans (cM), respectively. Recombination in female and male meiocytes showed no significant difference within this region. In a neighboring region between MWG865 and MWG503, the recombination frequency was higher in female than male meiocytes in one mapping population. The combined linkage data obtained from this study were compared with published data, and genotype-specific suppression of crossing-over was not evident in the vrs1 region.Key words: vrs1 locus (two- vs. six-rowed), molecular marker, recombination, backcross, Hordeum vulgare.
REVIEWS (1948)

REVIEWS Get access The First Epistle of Peter, the Greek Text with Introduction and Notes, by F. W. BEARE. Pp. x + 184. Oxford: Blackwell, 1947. 15s. T. W. MANSON T. W. MANSON Search for other works by this author on: Oxford Academic Google Scholar The Journal of Theological Studies, Volume os-XLIX, Issue 193-194, January-April 1948, Pages 85–86, https://doi.org/10.1093/jts/os-XLIX.193-194.85 Published: 01 April 1948
Novel Anti-fibrotic Therapies (2017)

Fibrosis is a major player in cardiovascular disease, both as a contributor to the development of disease, as well as a post-injury response that drives progression. Despite the identification of many mechanisms responsible for cardiovascular fibrosis, to date no treatments have emerged that have effectively reduced the excess deposition of extracellular matrix associated with fibrotic conditions. Novel treatments have recently been identified that hold promise as potential therapeutic agents for cardiovascular diseases associated with fibrosis, as well as other fibrotic conditions. The purpose of this review is to provide an overview of emerging antifibrotic agents that have shown encouraging results in preclinical or early clinical studies, but have not yet been approved for use in human disease. One of these agents is bone morphogenetic protein-7 (BMP7), which has beneficial effects in multiple models of fibrotic disease. Another approach discussed involves altering the levels of micro-RNA (miR) species, including miR-29 and miR-101, which regulate the expression of fibrosis-related gene targets. Further, the antifibrotic potential of agonists of the peroxisome proliferator-activated receptors will be discussed. Finally, evidence will be reviewed in support of the polypeptide hormone relaxin. Relaxin is long known for its extracellular remodeling properties in pregnancy, and is rapidly emerging as an effective antifibrotic agent in a number of organ systems. Moreover, relaxin has potent vascular and renal effects that make it a particularly attractive approach for the treatment of cardiovascular diseases. In each case, the mechanism of action and the applicability to various fibrotic diseases will be discussed.
Measuring interdependences in dissipative dynamical systems with estimated Fokker-Planck coefficients (2008)

We propose a data-driven approach to measure interdependences between dissipative dynamical systems under the influence of noise. We estimate drift and diffusion coefficients of a Fokker-Planck equation and derive measures that allow one to quantify the asymmetry in coupling in a fully automated and computationally inexpensive and simple way. Our approach makes it possible to discriminate between interdependences in the deterministic and stochastic parts of the dynamics. We report results of numerical studies of exemplary time series from coupled stochastic and deterministic model systems and of an application to electroencephalographic recordings from epilepsy patients.