gebhart/patrepeval huggingface dataset:
Application of superselective arterial embolization in treatment of acute arterial hemorrhage (2014)

Objective
To explore the application value of superselective arterial embolization in treatment of massive acute arterial hemorrhage.


Methods
Clinical data of 23 patients with acute arterial hemorrhage were analyzed retrospectively. The bleeding could not been controlled effectively in all patients with conservative treatment, underwent selective DSA and transcatheter arterial embolization with gelfoam particles (strips).


Results
DSA in all cases showed positive signs of bleeding, represented by contrast extravasation, vascular thickening, distortion, etc. Bleeding were stopped immediately after embolization in 21 cases. One case with cervical cancer had bleeding again after 10 h, thus had second embolization and had a satisfied result. One case with hemoptysis did not completely stop the bleeding, after active treatment with medicine bleeding was stopped. All patients had no serious complications.


Conclusions
DSA has high valuable in diagnosis of massive acute arterial hemorrhage. Superselective arterial embolization can quickly and effectively stop bleeding with fewer complications, could be used as the primary method in treatment of acute arterial hemorrhage.


Key words: 
Hemorrhage; Angiography; Embolization, therapeutic
A Brain Stem Reflex in the Blink of an Eye (1995)

The mammalian eyelid participates in blinking and eye movements. Blinking requires transient lid movements, whereas the lid movements accompanying eye movements additionally involve maintaining the lid in a new position. Eyelid control evolved so that the lid-closing muscle governs blinks and the lid-opening muscle determines lid position.
Retinoids and spermatogenesis: Lessons from mutant mice lacking the plasma retinol binding protein (2006)

Using Rbp4-null mice as models, we have established for the first time the kinetics of the spermatogenetic alterations during vitamin A deficiency (VAD). Our data demonstrate that the VAD-induced testicular degeneration arises through the normal maturation of germ cells in a context of spermatogonia differentiation arrest. They indicate that retinoic acid (RA) appears dispensable for the transition of premeiotic to meiotic spermatocytes, meiosis, and spermiogenesis. They confirm that RA plays critical roles in controlling spermatogonia differentiation, spermatid adhesion to Sertoli cells, and spermiation, and suggest that the VAD-induced arrest of spermatogonia differentiation results from simultaneous blocks in RA-dependent events mediated by RA receptor gamma (RARgamma) in spermatogonia and by RARalpha in Sertoli cells. They also provide evidence that expression of major RA-metabolizing enzymes is increased in mouse Sertoli cells upon VAD and that vitamin A-deficient A spermatogonia differ from their RA-sufficient counterparts by the expression of the Stra8 gene.
Recent Studies on Regulation of Gastric Motility in Turkeys (1992)

Recent studies have been aimed at determining how gastroduodenal contractions are initiated and at regulation of the stomach during the intestinal phase of gastric regulation. Intrinsic, myogenic, electrical slow waves, the principal regulators of motility in the mammalian gut, have not been found in the avian gut. Instead, contractions appear to be initiated by a neurogenic pacemaker located between the gastric isthmus and the pylorus. Pacemaker impulses travel over the myenteric plexus to the glandular stomach and the duodenum, and to the muscles of the muscular stomach to initiate contractions. Extrinsic innervation does not appear to be involved in this initiation. The role of two hormones, avian pancreatic polypeptide (aPP) and cholecystokinin (CCK), in regulation of gastric motility has been examined. Both hormones are released postprandially by the presence of ingesta in the upper small intestine and both depress gastroduodenal motility when administered to fowl. Thus, aPP and CCK slow gastric emptying to allow more time for intestinal digestion.
Role of Hirudin-like Factor Va Heavy Chain Sequences in Prothrombinase Function (2006)

Proexosite I on prothrombin has been implicated in providing a recognition site for factor Va within prothrombinase. To examine whether hirudin-like sequences (659-698) on the cofactor contribute to this interaction, we expressed and purified two-chain FVa derivatives that were intracellularly truncated at the C terminus of the heavy chain: FVa709 (des710-1545), FVa699 (des700-1545), FVa(692 (des693-1545), FVa678 (des679-1545), and FVa658 (des659-1545). We found that FVa709, FVa699, FVa692, and FVa678 exhibited specific clotting activities that were comparable with plasma-derived and recombinant FVa. Additionally, kinetic studies using prothrombin revealed that the Km and kcat values for these derivatives were unaltered. Fluorescent measurements and chromatography studies indicated that FVa709, FVa699, FVa692, and FVa678 bound to FXa membranes and thrombin-agarose in a manner that was comparable with the wild-type cofactors. In contrast, FVa658 had an approximately 1% clotting activity and reduced affinity for FXa membranes (approximately 20-fold) and did not bind to thrombin-agarose. Surprisingly, however, FVa(658) exhibited essentially normal kinetic parameters for prothrombin when the variant was fully saturated with FXa membranes. Overall our results are consistent with the interpretation that any possible binding interactions between prothrombin and the C-terminal region of the FVa heavy chain do not contribute in a detectable way to the enhanced function of prothrombinase.
Colorimetric Detection and Identification of Natural and Artificial Sweeteners (2009)

A disposable, low-cost colorimetric sensor array has been created by pin-printing onto a hydrophilic membrane 16 chemically responsive nanoporous pigments that are comprised of indicators immobilized in an organically modified silane (ormosil). The array has been used to detect and identify 14 different natural and artificial sweeteners at millimolar concentrations, as well as commonly used individual-serving sweetener packets. The array has shown excellent reproducibility and long shelf life and has been optimized to work in the biological pH regime.
Dual κ‐agonist/μ‐antagonist opioid receptor modulation reduces levodopa‐induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of<scp>P</scp>arkinson disease (2015)

Nalbuphine reverses the molecular milieu in the striatum associated with LID and is a safe and effective anti-LID agent in the primate model of PD. These findings support repurposing this analgesic for the treatment of LID.
Nested Miller compensation in low-power CMOS design (2001)

First, new stability conditions for low-power CMOS nested Miller compensated amplifiers are given in this brief. Then, an improved structure, which takes the advantages of a feedforward transconductance stage and a nulling resistor, is introduced. Experimental results prove that the proposed structure improves the frequency response, transient response, and power supply rejection ratio without increasing the power consumption and circuit complexity.
Increased protein yields from Escherichia coli using pressure-cycling technology. (2006)

Sample preparation is critical to the success of two-dimensional gel electrophoresis and other analytical methods. Pressure-cycling technology (PCT) uses alternating cycles of high and low pressure to induce cell lysis. Cell suspensions were placed in PULSE Tubes and subjected to alternating cycles of high and low pressure in a Barocycler instrument. each cycle consisted of 20 sec at 35,000 psi followed by 20 sec at ambient pressure. For the bacterium Escherichia coli, PCT extracted 14.2% more total protein than was extracted using a standard bead mill. Image analysis of two-dimensional gels revealed 801 protein spots in the PCT lysate, compared to 760 protein spots in the bead mill lysate.
Absolute Phase-Based Distance Measurement for Industrial Monitoring Systems (2009)

In this paper, principal considerations for a high accuracy millimeter wave (mmw) radar distance measurement system applicable to be used in harsh industrial environments are presented. The system is based on continuous wave (CW) measurement of the reflection coefficient and interpretation of the signal phase. The ambiguity of the phase is overcome by means of a multiple frequency technique. For absolute distance determination, an online calibration procedure is applied. The applicability of the system is underlined by a laboratory demonstrator measurement.
Structured light for three-dimensional microscopy (2006)

Part of the American Studies Commons This Dissertation is brought to you for free and open access by the Graduate School at Scholar Commons. It has been accepted for inclusion in Graduate Theses and Dissertations by an authorized administrator of Scholar Commons. For more information, please contact
Mechanism of Penetration of Antp(43−58) into Membrane Bilayers (2005)

Antp(43-58) is one of many peptides with basic and aromatic residues capable of crossing cell membranes efficiently in a receptor-independent manner. The basic-aromatic motif is responsible for peptide binding to the negatively charged surface of membrane bilayers. However, the mechanism of membrane penetration is unclear. We use high-resolution (1)H solution NMR methods to establish the location of the Antp(43-58) peptide bound to membrane bicelles composed of DMPC, DMPG, and DHPC, and compare it to the location of an Antp(43-58) variant which is not able to cross cell membranes. Two critical tryptophans are substituted with phenylalanine in this variant (W48F and W56F). Additional (31)P and (2)H NMR measurements of membrane bicelles are used to probe the changes in orientation of the lipid headgroups and the changes in the mobility or segmental order of the lipid acyl chains upon peptide binding. We find that Trp48 and Trp56 of Antp(43-58) insert into the hydrophobic core of the membrane and that this induces a change in the orientation of the negatively charged DMPG headgroups. The depth of insertion and the change in lipid orientation are concentration-dependent and argue for an electroporation-like mechanism for membrane penetration.
Waste-Derived Nanoparticles: Synthesis Approaches, Environmental Applications, and Sustainability Considerations (2020)

For the past few decades, a plethora of nanoparticles have been produced through various methods and utilized to advance technologies for environmental applications, including water treatment, detection of persistent pollutants, and soil/water remediation, amongst many others. The field of materials science and engineering is increasingly interested in increasing the sustainability of the processes involved in the production of nanoparticles, which motivates the exploration of alternative inputs for nanoparticle production as well as the implementation of green synthesis techniques. Herein, we start by overviewing the general aspects of nanoparticle synthesis from industrial, electric/electronic, and plastic waste. We expand on critical aspects of waste identification as a viable input for the treatment and recovery of metal- and carbon-based nanoparticles. We follow-up by discussing different governing mechanisms involved in the production of nanoparticles, and point to potential inferences throughout the synthesis processes. Next, we provide some examples of waste-derived nanoparticles utilized in a proof-of-concept demonstration of technologies for applications in water quality and safety. We conclude by discussing current challenges from the toxicological and life-cycle perspectives that must be taken into consideration before scale-up manufacturing and implementation of waste-derived nanoparticles.
Dopaminergic Modulation of Spinal Neuronal Excitability (2007)

It is well recognized that dopamine (DA) can modulate spinal networks and reflexes. DA fibers and receptors are present in the spinal cord, and evidence for DA release within the spinal cord has been published. A critical gap is the lack of data regarding dopaminergic modulation of intrinsic and synaptic properties of motoneurons and ventral interneurons in the mammalian spinal cord. In this paper, we address this issue by examining the cellular mechanisms underlying the excitatory effect of DA on motor systems. We examine the effects of DA on two classes of cells important for motor control, motoneurons and Hb9 interneurons, located in lamina VIII. We show that DA can boost excitability in spinal motoneurons by decreasing the first spike latency and the afterhyperpolarization. Collectively, this leads to an increase in the frequency-current slope likely attributable to modulation of I(A) and SK(Ca) (small-conductance calcium-activated K+ channel) currents. We also demonstrate that DA increases glutamatergic transmission onto motoneurons. Our data also suggest that DA stabilizes the rhythmic output of conditionally bursting interneurons. Collectively, these data indicate that DA has widespread actions on intrinsic and synaptic properties of ventral spinal neurons.
Electric Discharges in Plasma Chemistry (2008)

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Force and Pressure-Distribution Measurements on a Rectangular Wing With a Slotted Droop Nose and With Either Plain and Split Flaps in Combination or a Slotted Flap (1947)

Force measurements and pressure distribution measurements on the midsection were made on a rectangular wing with slotted droop nose and end plates, on which could be placed a choice of either a plain flap-split flap combination or a slotted flap. (author)
Solid‐like states of a dendrimer liquid displayed by scanning force microscopy (1996)

Abstract Adsorption and aggregation of carbosiloxane dendrimers on mica and pyrolytic graphite were investigated by scanning force microscopy (SFM). The aggregation process started from (i) single molecules which coagulated to (ii) clusters and (iii) fluid droplets followed by formation of (iv) a complete layer on the solid substrate. The molecules were displayed as a globular particle with a diameter of about 2.5 nm. Tapping SFM of the liquid was possible due to the fact that the dendrimer undergoes a transition to a viscoelastic state below the tapping frequency of about 360 kHz. Dynamic shear compliance experiments have shown a plateau of 5 · 10 −7 Pa −1 around this frequency. Dendrimer droplets slowly spread into polygonal lamellae with a thickness of two molecular layers. The structures indicate a rather regular dense packing of the globular molecules.
White Light Emission from Polymer Electrophosphorescent Light-Emitting Devices Doped with Iridium Complexes (2003)

We have fabricated simple polymer electrophosphorescent light-emitting devices based on a single emitting layer containing a hole-transporting host polymer, poly(N-vinylcarbazole), and an electron-transporting 1,3-bis[(4-tert-butylphenyl)-1,3,4-oxadiazolyl]phenylene, doped with iridium complexes. We obtained a white light emission, whose Commission Internationale de l'Eclairage color coordinates are x=0.33 and y=0.36, by double-doping with phosphorescent materials: 11.8 wt% blue-light-emitting bis[(4,6-difluorophenyl)-pyridinato-N,C2'](picolinate) iridium(III) and 0.2 wt% red-light-emitting bis[2-(2'-benzothienyl)pyridinato-N,C3'](acetylacetonate) iridium(III). At a practical luminance of 100 cd/m2, the external quantum efficiency of electroluminescence and the power luminous efficiency were 4.9% and 2.6 lm/W, respectively. This work demonstrates that high-efficiency white-light-emitting devices can be constructed from polymers and phosphorescent materials by using simple wet fabrication processes.
Charge and fluence lifetime measurements of a dc high voltage GaAs photogun at high average current (2011)

GaAs-based dc high voltage photoguns used at accelerators with extensive user programs must exhibit long photocathode operating lifetime. Achieving this goal represents a significant challenge for proposed high average current facilities that must operate at tens of milliamperes or more. This paper describes techniques to maintain good vacuum while delivering beam, and techniques that minimize the ill effects of ion bombardment, the dominant mechanism that reduces photocathode yield of a GaAs-based dc high voltage photogun. Experimental results presented here demonstrate enhanced lifetime at high beam currents by: (a) operating with the drive laser beam positioned away from the electrostatic center of the photocathode, (b) limiting the photocathode active area to eliminate photoemission from regions of the photocathode that do not support efficient beam delivery, (c) using a large drive laser beam to distribute ion damage over a larger area, and (d) by applying a relatively low bias voltage to the anode to repel ions created within the downstream beam line. A combination of these techniques provided the best total charge extracted lifetimes in excess of 1000 C at dc beam currents up to 9.5 mA, using green light illumination of bulk GaAs inside a 100 kV photogun.
Overexpression, purification, and characterization of UDP-N-acetylmuramyl:L-alanine ligase from Escherichia coli (1996)

UDP-N-acetylmuramyl:L-alanine ligase from Escherichia coli was overexpressed more than 600-fold and purified to near homogeneity. The purified enzyme was found to ligate L-alanine, L-serine, and glycine, as well as the nonnatural amino acid beta-chloro-L-alanine, to UDP-N-acetylmuramic acid. On the basis of (i) the specificity constants of the enzyme determined for L-alanine, L-serine, and glycine and (ii) the levels of these amino acids in the intracellular pool, it was calculated that the rates of incorporation of L-serine and glycine into peptidoglycan precursor metabolites could maximally amount to 0.1 and 0.5%, respectively, of the rate of L-alanine incorporation.
Defining a Role and Mechanism for Igcam Function in Vertebrate Axon Guidance (2000)

The past two decades of research on vertebrate neural adhesion molecules of the immunoglobulin superfamily class (IgCAMs) have produced an bewildering maze of molecules and potential binding activities (for review, see [Sonderegger 1998][1]). If one takes at equivalent face value the full range of
Youth and Tattoos: What School Health Personnel Should Know (2000)

Though tattooing has been practiced by various cultures for centuries, this art form has undergone dramatic changes the past few decades. Today, tattoos appeal to diverse populations and mainstream culture. The proliferation of tattooing prompted increased concern for safety and awareness of hazardous conditions. Transmission of infectious diseases, such as hepatitis B and C, and theoretically, HIV, can occur when proper sterilization and safety procedures are not followed. While there are many populations at risk, a critical at-risk group is adolescents. Tattooing among adolescents is a risk-taking behavior that warrants the attention of health education in assisting adolescents in becoming informed decision-makers. Teaching and advocacy strategies are suggested, and roles for school health personnel are presented.
Laparoscopic Retrieval of Spilled Stones (1992)

Spillage of gallstones during laparoscopic cholecystectomy is occasionally a problem. The use of a finger cut off of a size 9 sterile glove as an intraperitoneal sack facilitates the removal of these stones.
Pore pressure estimation from velocity data: accounting for overpressure mechanisms besides undercompaction (1994)

A new method for estimating pore pressure from formation sonic velocity data is presented. Unlike previous techniques, this method accounts for excess pressure generated by both undercompaction, and fluid expansion mechanisms such as aquathermal pressuring, hydrocarbon maturation, clay diagenesis, and charging from other zones. The method is an effective stress approach; the effective stress is computed from the velocity, and the result is subtracted from the overburden stress to obtain pore pressure. to include multiple sources of overpressure, a pair of velocity-vs.-effective-stress relations are introduced. One relation accounts for normal pressure and overpressure caused by undercompaction. The second is applied inside velocity reversal zones caused by fluid expansion mechanisms. Example applications of the method are presented from the U.S. gulf coast, the Gulf of Mexico, and the Central North Sea. some other pore pressure estimation approaches are also examined to demonstrate how these techniques have unknowingly accounted for overpressure mechanisms other than undercompaction. It is also explained how velocity-vs.-effective-stress data can be used to identify the general cause of overpressure in an area. For instance, the empirical correlation of Hottman and Johnson indicates that overpressure along the US gulf coast cannot be due only to undercompaction.
Synthesis, Properties, and Ternary Phase Stability of M <sub>6</sub> X Compounds in the Ti─Cu─O System (1993)

A section of the Ti─Cu─O ternary phase diagram was investigated at 925°C. The system contains two M 6 X‐type compounds, Ti 4 Cu 2 O and Ti 3 Cu 3 O, which are isostructural with the η‐carbides and are stabilized by O. The presence of two of these compounds and the size of their single‐phase fields contradict earlier predictions in the literature based on the valence and location of the elements in the periodic table. It is proposed that the atomic radii of the elements may also be a factor, especially for compounds containing Ti. The two observed M 6 X‐type compounds occur as products of reaction at the Ag─Cu─Ti/Al 2 O 3 interface. The compounds were synthesized in bulk for characterization of their properties which influence the performance of the brazed joints. The compounds are stable in inert atmospheres up to their melting points, but are easily oxidized in ambients containing even trace amounts of O and form a coherent layer of reaction products. The values of elastic coefficients, thermal expansion, and resistivity of these compounds are intermediate between those of Al 2 O 3 and Cu and would therefore provide a gradual transition across the interface.
Low-profile broadband mushroom and metasurface antennas (2017)

We present the recent progress in developing the mushroom and metasurface antennas for low-profile and broadband applications. The metamaterial-based mushroom antenna technology is first developed to realize broadband boresight-radiation with low profile on PCB and LTCC substrates operating from microwave to millimeter-wave bands. As a variation of the original mushroom antenna, vialess metasurface antennas are proposed along with miniaturization technique. Finally, the shorting-wall loaded mushroom antenna with new operating mechanism is reported as well.