gebhart/patrepeval huggingface dataset:
New Styrene-Maleic Anhydride Terpolymer Blends (1983)

A group of new, fully miscible, polymer blends consisting of various styrene-maleic anhydride terpolymers blended with styrene-acrylonitrile copolymer and rubber-modified versions of these materials have been prepared and investigated. In particular the effects of chemical composition of the components on heat resistance and the miscibility behavior of the blends have been elucidated. Toughness and response to elevated temperature air aging are also examined. Appropriate combinations of the components may be melt blended to provide an enhanced balance of heat resistance, chemical resistance, and toughness.
A surface-charge random-access memory system (1972)

The authors present a surface-charge storage cell suitable for word-organized dynamic random-access memory and discuss its operation in a memory system. Experimental results and computer simulations of the readout process on a 4/spl times/8 array using this cell are given. A sensitive stable sense-and-refresh amplifier, suitable for use with this memory cell is also described. Simulations of a 4096-bit chip with a storage cell density of 2.5 mils/SUP 2//bit using this refresh amplifier predict a cycle time of 250 ns.
Prognostic significance of Notch signalling molecules and their involvement in the invasiveness of endometrial carcinoma cells (2012)

The Notch1-JAG1 axis may enhance the invasive properties of endometrial carcinomas, which suggests the Notch pathway may be a promising target for the treatment of this malignancy.
Broccoli Consumption Interacts with GSTM1 to Perturb Oncogenic Signalling Pathways in the Prostate (2008)

ClinicalTrials.gov NCT00535977.
Modulation of the baboon ( <i>Papio anubis</i> ) uterine endometrium by chorionic gonadotrophin during the period of uterine receptivity (1999)

This study was undertaken to determine the modulation of uterine function by chorionic gonadotrophin (CG) in a nonhuman primate. Infusion of recombinant human CG (hCG) between days 6 and 10 post ovulation initiated the endoreplication of the uterine surface epithelium to form distinct epithelial plaques. These plaque cells stained intensely for cytokeratin and the proliferating cell nuclear antigen. The stromal fibroblasts below the epithelial plaques stained positively for alpha-smooth muscle actin (alphaSMA). Expression of alphaSMA is associated with the initiation of decidualization in the baboon endometrium. Synthesis of the glandular secretory protein glycodelin, as assessed by Western blot analysis, was markedly up-regulated by hCG, and this increase was confirmed by immunocytochemistry, Northern blot analysis, and reverse transcriptase-PCR. To determine whether hCG directly modulated these uterine responses, we treated ovariectomized baboons sequentially with estradiol and progesterone to mimic the hormonal profile of the normal menstrual cycle. Infusion of hCG into the oviduct of steroid-hormone-treated ovariectomized baboons induced the expression of alphaSMA in the stromal cells and glycodelin in the glandular epithelium. The epithelial plaque reaction, however, was not readily evident. These studies demonstrate a physiological effect of CG on the uterine endometrium in vivo and suggest that the primate blastocyst signal, like the blastocyst signals of other species, modulates the uterine environment prior to implantation.
STM/STS Observation of Polyoxoanions on HOPG Surfaces:  the Wheel-Shaped [Cu<sub>20</sub>Cl(OH)<sub>24</sub>(H<sub>2</sub>O)<sub>12</sub>(P<sub>8</sub>W<sub>48</sub>O<sub>184</sub>)]<sup>25</sup><sup>-</sup> and the Ball-Shaped [{Sn(CH<sub>3</sub>)<sub>2</sub>(H<sub>2</sub>O)}<sub>24</sub>{Sn(CH<sub>3</sub>)<sub>2</sub>}<sub>12</sub>(<i>A-</i>PW<sub>9</sub>O<sub>34</sub>)<sub>12</sub>]<sup>36</sup><sup>-</sup> (2006)

A combination of scanning tunneling microscopy (STM) and scanning tunneling spectroscopy (STS) techniques have been performed on the wheel-shaped [Cu20Cl(OH)24(H2O)12(P8W48O184)]25- and the ball-shaped [{Sn(CH3)2(H2O)}24{Sn(CH3)2}12(A-PW9O34)12]36- deposited on highly oriented pyrolytic graphite surfaces. Small, regular molecule clusters, as well as separated single molecules, were observed. The size of the molecules is in agreement with the data determined by X-ray crystallography. In STS measurements, we found a rather large contrast at the expected location of the Cu metal centers in our molecules, i.e., the location of the individual Cu ions in their organic matrix is directly addressable by STS.
Automatic inspection of turbine blades using 5-axis coordinate measurement machine (2010)

The complex geometric shape of turbine blades not only causes difficulties in fabrication but also makes it difficult to examine the part's precision when using a traditional 3-axis coordinate measurement machine (CMM). Generally speaking, one has to use a multi-axis CMM and follow the appropriately planned measuring paths to accomplish the task of precision measurement of the machined part. This article discusses the methodology of using a 3D geometric model of a turbine blade as the basis to generate interference-free measuring paths that are suitable for implementing on a CMM with three translational axes and two rotational axes. Through the use of the methodology proposed in this research, the goal of multi-axis precision inspection for any geometric design of turbine blade can be achieved.
A bibliography of the east surrey regiment (1931)

A bibliography of the east surrey regiment Get access J. Paine J. Paine Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume CLX, Issue jan24, 24 January 1931, Pages 59–60, https://doi.org/10.1093/nq/CLX.jan24.59 Published: 24 January 1931
CAD model for co-propagating spatially multiplexed channels of same wavelength over standard multimode fibers (2009)

Spatial Domain Multiplexing (SDM) is a novel technique that allows co-propagation of two or more optical communication channels of the same wavelengths over a single strand of optical fiber cable by maintaining spatial separation between the channels. Spatial multiplexer known as the beam combiner module (BCM) supports helical propagation of light to ensure spatial separation between the channels. It is inserted at the input end of the system. Spatial de-multiplexing is achieved by a unit named beam separator module (BSM). This unit is inserted at the receiving end of the system and it routes the optical energy from individual channels to dedicated receivers. Spatially multiplexed channels exhibit negligible crosstalk. The bandwidth of the fiber optic systems employing SDM technique increases by multiple folds. CAD model of a beam combiner module for a two channel system using commercially available simulation tools is presented here. Simulated beam profile of the output is compared to the experimental data.
Chips: A Tool for Developing Software Interfaces Interactively. (1987)

Abstract : Chips is an interactive tool for developing software employing graphical human/computer interfaces on Xerox Lisp machines. For the programmer, It provides a rich graphical interface for the creation of rich graphical interfaces. In the service of an end user, It provides classes for modeling the graphical relationships of objects on the screen and maintaining constraints between them. Several large applications have been developed with Chips including intelligent tutors for programming and electricity. Chips is implemented as a collection of customizable classes in the LOOPS object-oriented extensions to Interlisp-D. The three fundamental classes are: 1) DomainObject which defines objects of the application domain - the domain for which the interface is being built - and ties together the various functionalities provided by the Chips system; 2) DisplayObject which defines mouse-sensitive graphical objects; and 3) Substrate which defines specialized windows for displaying and storing collections of instances of DisplayObject. A programmer creates an interface by specializing existing DomainObjects and drawing new Displayobjects with a graphics editor. Instances of DispalyObject and Substrate are assembled on screen to form the interface. Once the interface has been sketched in this manner, the programmer can build inward, creating all other parts of the application through the objects on the screen.
Effect of Natural Protease Inhibitors and a Chemoattractant on Tumor Cell Invasion In Vitro (1982)

The effect of natural protease inhibitors and a chemoattractant on tumor cell invasion were studied with the use of a new in vitro quantitative assay of tumor cell penetration of native connective tissue. Human amnion membrane denuded of its epithelium is composed of a continuous basement membrane (BM) attached to a dense avascular collagenous stroma. M5076 reticulum sarcoma cells, known to be highly invasive in vivo, were placed on the BM side of the amnion connective tissue. Tumor cells penetrating the full thickness of the connective tissue barrier were collected on the stromal side with a Millipore filter. N-Formylmethionyl-leucyl-phenylalanine (FMLP) at an optimal concentration of 10(-7) M stimulated the penetration of up to 600% more tumor cells into the connective tissue after 20 hours in comparison to the number of tumor cells spontaneously penetrating in serum-free media. Natural protease inhibitors blocked both FMLP-stimulated and spontaneous invasion. A bovine cartilage extract containing inhibitors of both serine proteinases and metalloproteinases caused a 500% decrease in invasion. Furthermore, a 500% inhibition of invasion was produced by a purified collagenase (metalloproteinase) inhibitor. In contrast, soybean trypsin inhibitor and bovine serum albumin did not significantly alter the invasion rate. The protease inhibitors were nontoxic and did not reduce tumor cell proliferation, attachment to the amnion, and the rate of tumor cell migration through Nuclepore filters. These data support the hypothesis that collagenolytic metalloproteinases play a necessary role in tumor cell invasion of native connective tissue.
PALLADIUM DOPED TIN OXIDE BASED HYDROGEN GAS SENSORS FOR SAFETY APPLICATIONS (2010)

Hydrogen is considered to be a hazardous gas since it forms a flammable mixture between 4 to 75% by volume in air. Hence, the safety aspects of handling hydrogen are quite important. For this, ideally, highly selective, fast response, small size, hydrogen sensors are needed. Although sensors based on different technologies may be used, thin‐film sensors based on palladium (Pd) are preferred due to their compactness and fast response. They detect hydrogen by monitoring the changes to the electrical, mechanical or optical properties of the films. We report the development of Pd‐doped tin‐oxide based gas sensors prepared on thin ceramic substrates with screen printed platinum (Pt) contacts and integrated nicrome wire heaters. The sensors are tested for their performances using hydrogen—nitrogen gas mixtures to a maximum of 4% H2 in N2. The sensors detect hydrogen and their response times are less than a few seconds. Also, the sensor performance is not altered by the presence of helium in the test gas mixtures. By the above desired performance characteristics, field trials of these sensors have been undertaken. The paper presents the details of the sensor fabrication, electronic circuits, experimental setup for evaluation and the test results.
Treatment of Experimental Escherichia Coli Infection in Mice with Colicine V (1977)

Concentrated non-toxic preparations of colicine V were obtained by filtering centrifugates of soft-agar cultures of a Col V+ K12 strain of E. coli through Millipore filters in which the colicine V was retained. These preparations, given subcutaneously, favourably influenced the course of disease in mice infected intraperitoneally with a pathogenic strain of E. coli that was very sensitive to colicine V in vitro. A beneficial effect was noted even when treatment was delayed until the mice were visibly ill.
Late surge glacial conditions on Bakaninbreen, Svalbard, and implications for surge termination (2002)

Bakaninbreen is a polythermal glacier in southern Spitsbergen, Svalbard, that last surged between 1985 and 1995. Seismic reflection data were acquired during early quiescence in spring 1998, just upstream of the surge front. The results were combined with complementary ground‐penetrating radar data to investigate the glacial structure and basal conditions. We find no difference between the ice thickness values determined from the seismic and radar methods, suggesting that any layer of basal ice cannot be greater than ∼5 m thick. Interpretation of the amplitude of the seismic reflections indicates the presence of permafrost close to the glacier base. A thin layer of thawed deforming sediment separates the glacier from this underlying permafrost. In an area just upstream of the surge front the permafrost becomes discontinuous and may even be absent, the ice being underlain by 10–15 m of thawed sediments overlying deeper bedrock. High‐pressure water is believed to have been required to maintain the propagation of the surge, and this area of thawed sediment is interpreted as a route for that water to escape from the basal system. When the surge front passed over this thawed bed, the escaping water reduced the pressure in the subglacial hydraulic system, initiating the termination of the surge. Surge termination was therefore primarily controlled by the presurge permafrost distribution beneath the glacier, rather than any feature of the surge itself. This termination mechanism is probably limited to surges in polythermal glaciers, but the techniques used may have wider glaciological applications.
Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure (2013)

In congestive heart failure (CHF), carotid body (CB) chemoreceptor activity is enhanced and is associated with oscillatory (Cheyne-Stokes) breathing patterns, increased sympathetic nerve activity (SNA) and increased arrhythmia incidence. We hypothesized that denervation of the CB (CBD) chemoreceptors would reduce SNA, reduce apnoea and arrhythmia incidence and improve ventricular function in pacing-induced CHF rabbits. Resting breathing, renal SNA (RSNA) and arrhythmia incidence were measured in three groups of animals: (1) sham CHF/sham-CBD (sham-sham); (2) CHF/sham-CBD (CHF-sham); and (3) CHF/CBD (CHF-CBD). Chemoreflex sensitivity was measured as the RSNA and minute ventilatory (VE) responses to hypoxia and hypercapnia. Respiratory pattern was measured by plethysmography and quantified by an apnoea-hypopnoea index, respiratory rate variability index and the coefficient of variation of tidal volume. Sympatho-respiratory coupling (SRC) was assessed using power spectral analysis and the magnitude of the peak coherence function between tidal volume and RSNA frequency spectra. Arrhythmia incidence and low frequency/high frequency ratio of heart rate variability were assessed using ECG and blood pressure waveforms, respectively. RSNA and VE responses to hypoxia were augmented in CHF-sham and abolished in CHF-CBD animals. Resting RSNA was greater in CHF-sham compared to sham-sham animals (43 ± 5% max vs. 23 ± 2% max, P < 0.05), and this increase was not found in CHF-CBD animals (25 ± 1% max, P < 0.05 vs. CHF-sham). Low frequency/high frequency heart rate variability ratio was similarly increased in CHF and reduced by CBD (P < 0.05). Respiratory rate variability index, coefficient of variation of tidal volume and apnoea-hypopnoea index were increased in CHF-sham animals and reduced in CHF-CBD animals (P < 0.05). SRC (peak coherence) was increased in CHF-sham animals (sham-sham 0.49 ± 0.05; CHF-sham 0.79 ± 0.06), and was attenuated in CHF-CBD animals (0.59 ± 0.05) (P < 0.05 for all comparisons). Arrhythmia incidence was increased in CHF-sham and reduced in CHF-CBD animals (213 ± 58 events h(-1) CHF, 108 ± 48 events h(-1) CHF-CBD, P < 0.05). Furthermore, ventricular systolic (3.8 ± 0.7 vs. 6.3 ± 0.5 ml, P < 0.05) and diastolic (6.3 ± 1.0 vs. 9.1 ± 0.5 ml, P < 0.05) volumes were reduced, and ejection fraction preserved (41 ± 5% vs. 54 ± 2% reduction from pre-pace, P < 0.05) in CHF-CBD compared to CHF-sham rabbits. Similar patterns of changes were observed longitudinally within the CHF-CBD group before and after CBD. In conclusion, CBD is effective in reducing RSNA, SRC and arrhythmia incidence, while improving breathing stability and cardiac function in pacing-induced CHF rabbits.
Hydrophilic Organic Electrodes on Flexible Hydrogels (2015)

Prompted by the rapidly developing field of wearable electronics, research into biocompatible substrates and coatings is intensifying. Acrylate-based hydrogel polymers have gained widespread use as biocompatible articles in applications such as contact and intraocular lenses. Surface treatments and/or coatings present one strategy to further enhance the performance of these hydrogels or even realize novel functionality. In this study, the conductive polymer poly(3,4-ethylenedioxythiophene) (PEDOT) is deposited from the vapor phase onto hydrated hydrogel substrates and blended with biocompatibilizing coconstituents incorporating polyethylene glycol (PEG) and polydimethyl siloxane (PDMS) moieties. Plasma pretreatment of the dehydrated hydrogel substrate modifies its surface topography and chemical composition to facilitate the attachment of conductive PEDOT-based surface layers. Manipulating the vapor phase polymerization process and constituent composition, the PEDOT-based coating is engineered to be both hydrophilic (i.e. to promote biocompatibility) and highly conductive. The fabrication of this conductively coated hydrogel has implications for the future of wearable electronic devices.
ChemInform Abstract: Encyclopedia of the Chemical Elements (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Comparison of Axillary Bud Growth and Patatin Accumulation in Potato Leaf Cuttings as Assays for Tuber Induction* (1988)

Single-node leaf cuttings from potatoes (Solanum tuberosum L.) cvs. Norland, Superior, Norchip, and Kennebec, were used to assess tuber induction in plants grown under 12, 16, and 20 h daily irradiation (400 micromol s-1 m-2 PPF). Leaf cuttings were taken from plants at four, six and 15 weeks after planting and cultured for 14 d in sand trays in humid environments. Tuber induction was determined by visually rating the type of growth at the attached axillary bud, and by measuring the accumulation of the major tuber protein, patatin, in the base of the petioles. Axillary buds from leaf cuttings of plants grown under the 12 h photoperiod consistently formed round, sessile tubers at the axils for all four cultivars at all harvests. Buds from cuttings of plants grown under the 16 and 20 h photoperiods exhibited mixed tuber, stolon, and leafy shoot growth. Patatin accumulation was highest in petioles of cuttings taken from 12 h plants for all cultivars at all harvests, with levels in 16 and 20 h cuttings approx. one-half that of the 12 h cuttings. Trends, both in visual ratings of axillary buds and in petiole patatin accumulation, followed the harvest index (ratio of tuber to total plant dry matter), suggesting that either method is an acceptable assay for tuber induction in the potato.
Broken flow symmetry explains the dynamics of small particles in deterministic lateral displacement arrays (2017)

Deterministic lateral displacement (DLD) is a technique for size fractionation of particles in continuous flow that has shown great potential for biological applications. Several theoretical models have been proposed, but experimental evidence has demonstrated that a rich class of intermediate migration behavior exists, which is not predicted. We present a unified theoretical framework to infer the path of particles in the whole array on the basis of trajectories in a unit cell. This framework explains many of the unexpected particle trajectories reported and can be used to design arrays for even nanoscale particle fractionation. We performed experiments that verify these predictions and used our model to develop a condenser array that achieves full particle separation with a single fluidic input.
Introduction to Exploration Geophysics, Vol. 45, No. 4 (2015)

英文誌「Exploration Geophysics」の内容を広く会員に紹介するために,掲載論文の要旨の翻訳を本誌に掲載する。今回は,英文誌のVol. 45 No. 4の要旨を紹介する。著者による原著という注釈があるもの以外,要旨の翻訳は会誌編集委員会にて実施した。興味をもたれた論文に関しては,是非とも電子出版されたオリジナル版をチェックいただきたい。なお,英文誌に掲載された論文は,本学会のホームページ経由で閲覧可能である。具体的には,本学会トップページ右側のバナー一覧のうち「Exploration Geophysics download site」を選択し,ウエブページ上の指示に従い,会員認証後PDFダウンロード可能となる。
Assessing the Tendency of Fluorescent Proteins to Oligomerize Under Physiologic Conditions (2012)

Several fluorescent proteins (FPs) are prone to forming low-affinity oligomers. This undesirable tendency is exacerbated when FPs are confined to membranes or when fused to naturally oligomeric proteins. Oligomerization of FPs limits their suitability for creating fusions with proteins of interest. Unfortunately, no standardized method evaluates the biologically relevant oligomeric state of FPs. Here, we describe a quantitative visual assay for assessing whether FPs are sufficiently monomeric under physiologic conditions. Membrane-associated FP-fusion proteins, by virtue of their constrained planar geometry, achieve high effective concentrations. We exploited this propensity to develop an assay to measure FP tendencies to oligomerize in cells. FPs were fused on the cytoplasmic end of an endoplasmic reticulum (ER) signal-anchor membrane protein (CytERM) and expressed in cells. Cells were scored based on the ability of CytERM to homo-oligomerize with proteins on apposing membranes and restructure the ER from a tubular network into organized smooth ER (OSER) whorl structures. The ratio of nuclear envelope and OSER structures mean fluorescent intensities for cells expressing enhanced green fluorescent protein (EGFP) or monomeric green fluorescent protein (mGFP) CytERM established standards for comparison of uncharacterized FPs. We tested three FPs and identified two as sufficiently monomeric, while a third previously reported as monomeric was found to strongly oligomerize.
A single-polysilicon flip-flop EEPROM for ASIC application (2003)

A single-polysilicon flip-flop EEPROM has been developed. A single-polysilicon structure which is suitable for ASIC (application-specific integrated circuit) application and a flip-flop-type cell give an endurance of more than 1,000,000 cycles. With this technology, a one-chip computer with CPU, RAM, ROM, some I/O ports, and EEPROM has been fabricated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>