gebhart/patrepeval huggingface dataset:
Molecular Genetic Dissection of Quantitative Trait Loci Regulating Rice Grain Size (2014)

Grain size is one of the most important factors determining rice yield. As a quantitative trait, grain size is predominantly and tightly controlled by genetic factors. Several quantitative trait loci (QTLs) for grain size have been molecularly identified and characterized. These QTLs may act in independent genetic pathways and, along with other identified genes for grain size, are mainly involved in the signaling pathways mediated by proteasomal degradation, phytohormones, and G proteins to regulate cell proliferation and cell elongation. Many of these QTLs and genes have been strongly selected for enhanced rice productivity during domestication and breeding. These findings have paved new ways for understanding the molecular basis of grain size and have substantial implications for genetic improvement of crops.
Gas Separation Membrane Applications (2001)

Introduction Membrane application development Membrane selection Membrane form Membrane module geometry Compatible sealing materials Module manufacture Pilot or field demonstration Process design Membrane system Beta site Cost/performance Commercial gas separation membrane applications Hydrogen separations Helium separations Nitrogen generation Acid gas separations Gas dehydration Developing membrane applications Oxygen and oxygen enriched air Nitrogen enriched air (NEA) Nitrogen rejection from natural gas
Identification of Some DNA Damage-Inducible Genes of <i>Mycobacterium tuberculosis</i> : Apparent Lack of Correlation with LexA Binding (2001)

The repair of DNA damage is expected to be particularly important to intracellular pathogens such as Mycobacterium tuberculosis, and so it is of interest to examine the response of M. tuberculosis to DNA damage. The expression of recA, a key component in DNA repair and recombination, is induced by DNA damage in M. tuberculosis. In this study, we have analyzed the expression following DNA damage in M. tuberculosis of a number of other genes which are DNA damage inducible in Escherichia coli. While many of these genes were also induced by DNA damage in M. tuberculosis, some were not. In addition, one gene (ruvC) which is not induced by DNA damage in E. coli was induced in M. tuberculosis, a result likely linked to its different transcriptional arrangement in M. tuberculosis. We also searched the sequences upstream of the genes being studied for the mycobacterial SOS box (the binding site for LexA) and assessed LexA binding to potential sites identified. LexA is the repressor protein responsible for regulating expression of these SOS genes in E. coli. However, two of the genes which were DNA damage inducible in M. tuberculosis did not have identifiable sites to which LexA bound. The absence of binding sites for LexA upstream of these genes was confirmed by analysis of LexA binding to overlapping DNA fragments covering a region from 500 bp upstream of the coding sequence to 100 bp within it. Therefore, it appears most likely that an alternative mechanism of gene regulation in response to DNA damage exists in M. tuberculosis.
Caveolin-1 Deficiency Increases Cerebral Ischemic Injury (2007)

Caveolins (Cav), the principal structural proteins of the caveolar domains, have been implicated in the pathogenesis of ischemic injury. Indeed, changes in caveolin expression and localization have been reported in renal and myocardial ischemia. Genetic ablation of the Cav-1 gene in mice was further shown to increase the extent of ischemic injury in a model of hindlimb ischemia. However, the role of Cav-1 in the pathogenesis of cerebral ischemia remains unknown. Immunoblot and immunofluorescence analyses of rat brains subjected to middle cerebral artery occlusion revealed marked increases in endothelial Cav-1 and Cav-2 protein levels. To directly assess the functional role of caveolins in the pathogenesis of cerebral ischemic injury, we next investigated the effects of cerebral ischemia in caveolin knockout (KO) mice. Interestingly, Cav-1 KO mice showed a marked increase of cerebral volume of infarction, as compared with wild-type and Cav-2 KO mice. Immunofluorescence analyses showed an increased number of proliferating endothelial cells in wild-type ischemic brains, as compared with Cav-1 KO ischemic brains. Immunoblot analyses of wild-type ischemic brains showed an increase in endothelial nitric oxide synthase protein levels. Conversely, the protein levels of endothelial nitric oxide synthase remained unchanged in Cav-1 KO ischemic brains. TUNEL analysis also showed increased apoptotic cell death in Cav-1 KO ischemic brains, as compared with wild-type ischemic brains. Our findings indicate cerebral ischemia induces a marked increase in endothelial Cav-1 and Cav-2 protein levels. Importantly, genetic ablation of the Cav-1 gene in mice results in increased cerebral volume of infarction. Mechanistically, Cav-1 KO ischemic brains showed impaired angiogenesis and increased apoptotic cell death.
Mineral Contents of Indonesian Seaweeds and Mineral Solubility Affected by Basic Cooking (2006)

This experiment was carried out to study the mineral contents and profiles of several Indonesian green, brown, and red seaweeds, and to evaluate the solubilities of Ca and Mg as affected by boiling in different solutions (water, 1% sodium chloride and 0.5% acetic acid). The macromineral profiles were dominated by Ca, K, Na and Mg. The trace minerals Cu, Fe and Zn were found at low concentrations. Boiling in water and 0.5% acetic acid significantly increased the solubilities of Ca and Mg (p<0.05), whereas boiling in 1% sodium chloride resulted in varying solubilities of Ca and Mg. Mainly soluble Ca was found in both low (MW<10,000) and high (MW>200,000) molecular weight fractions, whereas soluble Mg was found in the high (MW>200,000) molecular weight fraction.
Strong recoverability in multidatabase systems (2003)

A multidatabase system (MDBS) consists of a number of multiple autonomous database management systems (DBMSs) in which global transactions are executed under the control of the MDBS, and local transactions are executed under the control of a local DBMS. Each local DBMS ensures local serializability. The function of the MDBS is to ensure global serializability. The major difficulty in ensuring global serializability stems from the fact that in the presence of local transactions, and without any restrictions on the local concurrency control of the participating local DBMSs., even serial execution of global transactions does not guarantee global serializability. These difficulties could be avoided if the serialization order of transactions were always the same as their commitment order. The authors study the class of transaction scheduling mechanisms in which transaction serialization order can be determined by controlling their commitment order. They use these results to design a multidatabase transaction management scheme that ensures global serializability.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Physicochemical characterization of hydrogels based on polyvinyl alcohol–vinyl acetate blends (2001)

Abstract Hydrogels made of polyvinyl alcohol–vinyl acetate and its blends with water soluble polymer were studied in terms of swelling behavior, microstructure, and dynamic mechanical properties. Hydrogels prepared by blending polyvinyl alcohol–vinyl acetate with either polyacrylic acid or poly(4‐vinyl pyridine) exhibited a strong pH dependency. When poly(vinyl pyrrolidone) was used for blending, an unusual pH dependency was observed. An increase in the equilibrium water content in all systems resulted in an increase in the freezable water as determined by DSC. Critical point drying led to a striated surface on polyacrylic acid–polyvinyl alcohol–vinyl acetate hydrogels, whereas a porous structure was observed on the freeze‐dried poly(vinyl pyrrolidone)–polyvinyl alcohol–vinyl acetate gels. Hydrogels with elevated storage modulus were obtained when either polyvinyl alcohol–vinyl acetate alone or polyacrylic acid–polyvinyl alcohol–vinyl acetate blends were thermally treated at high temperatures (i.e., 150°C). Low storage modulus was observed for both poly(vinyl pyrrolidone) and poly(4‐vinyl pyridine)‐containing hydrogels. Temperature dependency of storage modulus from 20 to 60°C was observed only for poly(4‐vinyl pyridine)–polyvinyl alcohol–vinyl acetate hydrogels. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 82: 3578–3590, 2001
Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) Fluorides (2018)

The design, synthesis, and application of [4-(acetylamino)phenyl]imidodisulfuryl difluoride (AISF), a shelf-stable, crystalline reagent for the synthesis of sulfur(VI) fluorides, is described. The utility of AISF is demonstrated in the synthesis of a diverse array of aryl fluorosulfates and sulfamoyl fluorides under mild conditions. Additionally, a single-step preparation of AISF was developed that installed the bis(fluorosulfonyl)imide group on acetanilide utilizing an oxidative C-H functionalization protocol.
Network+ Exam Prep 2 (Exam Prep N10-003) (Exam Cram 2) (2005)

Attention Network+ Candidates: Stop spending valuable study time sorting through confusing study aids. Network + Exam Prep 2 is the ultimate self-study guide for the Network + exam. Featuring exercises, self-assessments, study strategies, exam tips and notes, this comprehensive guide will help you understand the concepts behind the exam objectives and score better on the test. You will also receive a CD that includes over 100 practice test questions and the Cram Sheet tear card for last-minute test review. Network + Exam Prep 2 is the smarter, more efficient way to get certified.
A Comparison of the Mechanical Properties of Fiberglass Cast Materials and Their Clinical Relevance (1990)

The mechanical properties of five synthetic fiberglass casting materials were evaluated and compared with the properties of plaster of Paris. Two of the tests were designed to bear clinical relevance and the third to determine intrinsic material properties. The effect of water on strength degradation was also evaluated. It was found that the synthetics as a group are far superior to plaster of Paris in all methods of testing and that, among the synthetics, KCast Tack Free, Deltalite "S", and KCast Improved were the stronger materials. Clinically, the most important results are that the synthetics attain their relatively high strength in a much shorter time frame than does plaster of Paris, and retain 70-90% of their strength after being immersed in water and allowed to dry.
[Ultrastructural immunocytochemical localization of diphosphate kinase/Nm23 in human cancer cells]. (1992)

Nucleoside diphosphate (NDP) kinase/Nm23 is highly expressed in certain malignant tissues, as compared with the rate found in normal or hyperplastic tissues. The potential role of this overexpression in tumor progression and the mechanisms involved in it remain to be determined. We studied the ultrastructural localisation of the NDP kinase, and in particular looked for an association of this enzyme with the microtubules or cytoplasmic membrane. Using immunocytochemical methods with an antiserum raised against NDP kinase A, we analysed tissue sections of breast carcinomas and cells in culture derived from a cervical cancer. In malignant cells, a strong labeling of the cytoplasm, related to ribosomes, was observed. No labeling of microtubules, or other intracytoplasmic components was found. No labeling of the nucleus was noted. In contrast, a strong labeling of the cytoplasmic membrane of most malignant cells was observed. In the cytoplasm of non-malignant stromal cells, a slight labeling of ribosomes was observed. These results must be taken into account with regard to the different existing hypotheses relative to the role of the NDP kinase in tumor progression, and in particular relative to its activation function on the GTP-binding proteins involved in membrane signal transduction.
Micro-architectured materials: past, present and future (2010)

Micro-architectured materials offer the opportunity of obtaining unique combinations of material properties. First, a historical perspective is given to the expansion of material property space by the introduction of new alloys and new microstructures. Principles of design of micro-architecture are then given and the role of nodal connectivity is emphasized for monoscale and multi-scale microstructures. The stiffness, strength and damage tolerance of lattice materials are reviewed and compared with those of fully dense solids. It is demonstrated that micro-architectured materials are able to occupy regions of material property space (such as high stiffness, strength and fracture toughness at low density) that were hitherto empty. Some challenges for the development of future materials are highlighted.
Moving beyond definitions: what student-generated models reveal about their understanding of covalent bonding and ionic bonding (2013)

Chemistry students encounter a variety of terms, definitions, and classification schemes that many instructors expect students to memorize and be able to use. This research investigated students' descriptions of ionic and covalent bonding beyond definitions in order to explore students' knowledge about chemical bonding. Using Johnstone's Multiple Levels of Representation framework, an interactive interview protocol was designed to explore secondary and first year university chemistry students' understandings of bonding. This paper reports findings from the first phase of the interview when students were asked to create models to depict and explain covalent and ionic bonding using art supplies. Analysis of the student generated models and their accompanying explanations revealed multiple misconceptions about covalent and ionic bonding even though students could recite definitions.
Fine line printed and plated contacts on high ohmic emitters enabling 20% cell efficiency (2009)

The contact performance of seed-layer printed, fired and plated (SFP) contacts were studied on solar cells with different emitter sheet resistivities. For the seed layer of the SFP-contacts a special metal ink called SISC (seed layer ink for the metallization of solar cells), developed and fabricated at Fraunhofer ISE to contact lowly doped emitters was used. The doping profile and the surface concentration of active phosphorus are determined by secondary ion mass spectroscopy (SIMS) and by electrochemical capacitance voltage (ECV) measurements. Large-area Cz-silicon solar cells 12.5 × 12.5 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> were fabricated with sheet resistivities between 40 ¿/sq. and 130 ¿/sq. The cells are metalized with SFP-contacts and conventional screen print contacts for comparison. High fill factors above 79% on solar cells with lowly doped emitters (sheet resistance of 130 ¿/sq.) could be achieved with SFP-contacts. In contrast, for screen-printed contacts using standard Ag paste the FFs for such lowly doped emitters are reduced to values around 55%. The difference in contact formation is explained by contact resistance measurements together with images from the metal semiconductor junction. Using the SISC ink solar cells with 45 ¿m wide contact structures were processed on a high efficiency cell structure with a passivated rear surface and a 110 ¿/sq. emitter a FF of 81% was achieved resulting in a cell efficiency of ¿=20.6%.
Ethylene–Norbornene Copolymerization by Carbon Nanotube‐Supported Metallocene Catalysis: Generation of High‐Performance Polyolefinic Nanocomposites (2007)

Abstract Homogeneous surface coating of multi‐walled carbon nanotubes is achieved for the first time by in situ copolymerization of ethylene (E) and 2‐norbornene (N) as catalyzed directly from the nanotube surface previously treated by a highly active metallocene‐based complex, i.e., rac ‐Et(Ind) 2 ZrCl 2 /MMAO‐3A. The copolymerization reaction allows for the destructuration of the native nanotube bundles, which upon further melt blending with an ethylene–vinyl acetate copolymer (27 wt.‐% vinyl acetate) matrix, leads to high‐performance polyolefinic nanocomposites. The microstructural analysis of the surface‐coating copolymer was carried out by 13 C NMR spectroscopy and allowed determination of the actual N content incorporated along the chains. Depending on the experimental conditions used (e.g., E pressure, solvent, feed N concentration) the relative quantity of E–N copolymer can be tuned, as well as the N content in the formed copolymers and accordingly their glass transition temperature. magnified image
High levels of 8-hydroxy-2′-deoxyguanosine appear in normal human epidermis after a single dose of ultraviolet radiation (1999)

Major photoproducts induced by carcinogenic ultraviolet (UV) radiation are the cylobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone (6-4) photoproducts (6-4 PPs). 8-Hydroxy-2 -deoxyguanosine (8-OHdG) is also a DNA base-modified product generated by reactive oxygen species in conditions of ultraviolet stress, Although UVB-induced CPDs and 6-4 PPs have been investigated in animal and human skin, little is known about the role of 8-OHdG in UVB-induced human skin damage or carcinogenesis. Normal human skin from three volunteers was exposed to UV radiation, and the time course of induction and removal of 8-OHdG was examined by immunohistochemical analysis with catalysed signal amplification on formalin-fixed paraffin sections. Formation of CPDs and 6-4 PPs was also examined by immunostaining on the same skin specimens. Control epidermis with no exposure to UV radiation showed little nuclear staining of 8-OHdG, but an increased level of 8-OHdG was clearly observed in epidermis biopsied after irradiation. Induced 8-OHdG can rapidly be removed from nucleus during the first 24-48 h, as the staining intensity diminished gradually, almost reaching the control level by 72-96 h after irradiation. Staining for CPDs or 6-4 PPs revealed induction of these photoproducts in human skin, although 6-4 PP-positive cells disappeared more rapidly than those that stained for CPDs or 8-OHdG. Together with protective effect of antioxidants, our results indicate that not only CPDs and 6-4 PPs but also 8-OHdG may play a significant part in UV carcinogenesis.
BLOOD VOLUME IN THE PREGNANT RABBIT (1982)

Red cell and plasma volumes were measured using 51Cr-labelled red cells and 125I-labelled HSA respectively, in seventeen pregnant rabbits at 28-29 days of pregnancy, and fifteen non-pregnant rabbits weight-matched with the pregnancy rabbits before mating. Red cell volume in the pregnant group (20.0 +/- 2.8 ml . kg-1; mean +/- S.D.), was greater than in the control rabbits (18.0 +/- 2.0 ml . kg-1; P less than 0.05); plasma volumes (39.0 +/- 4.5 and 37.3 +/- 4.4 ml . kg-1 respectively) were not statistically different. Blood volume was derived from the sum of independently measured red cell and plasma volumes. That of the pregnant group (59.0 +/- 5.3 ml . kg-1) was just significantly greater than that of control rabbits (55.3 +/- 5.3 ml . kg-1; P less than 0.05). When the volume of distribution of the labels was corrected, by subtracting fetal weight from maternal body weight, the red cell, plasma and blood volumes were all significantly greater in the pregnant rabbits (P less than 0.02). Although the large vessel haematocrit of the pregnant group (41.6 +/- 4.4%) exceeded that of the non-pregnant group (38.7 +/- 2.6%; P less than 0.05), there was no significant difference in whole body haematocrit or Fcells (the ratio of the whole body to large vessel haematocrit) between the two group of rabbits.
IMP4GT: IMPersonation Attacks in 4G NeTworks (2020)

Long Term Evolution (LTE/4G) establishes mutual authentication with a provably secure Authentication and Key Agreement (AKA) protocol on layer three of the network stack. Permanent integrity protection of the control plane safeguards the traffic against manipulations. However, missing integrity protection of the user plane still allows an adversary to manipulate and redirect IP packets, as recently demonstrated.
Effects of pulsed magnetic stimulation on tumor development and immune functions in mice (2005)

We investigated the effects of pulsed magnetic stimulation on tumor development processes and immune functions in mice. A circular coil (inner diameter = 15 mm, outer diameter = 75 mm) was used in the experiments. Stimulus conditions were pulse width = 238 micros, peak magnetic field = 0.25 T (at the center of the coil), frequency = 25 pulses/s, 1,000 pulses/sample/day and magnetically induced eddy currents in mice = 0.79-1.54 A/m(2). In an animal study, B16-BL6 melanoma model mice were exposed to the pulsed magnetic stimulation for 16 days from the day of injection of cancer cells. A tumor growth study revealed a significant tumor weight decrease in the stimulated group (54% of the sham group). In a cellular study, B16-BL6 cells were also exposed to the magnetic field (1,000 pulses/sample, and eddy currents at the bottom of the dish = 2.36-2.90 A/m(2)); however, the magnetically induced eddy currents had no effect on cell viabilities. Cytokine production in mouse spleens was measured to analyze the immunomodulatory effect after the pulsed magnetic stimulation. tumor necrosis factor (TNF-alpha) production in mouse spleens was significantly activated after the exposure of the stimulus condition described above. These results showed the first evidence of the anti-tumor effect and immunomodulatory effects brought about by the application of repetitive magnetic stimulation and also suggested the possible relationship between anti-tumor effects and the increase of TNF-alpha levels caused by pulsed magnetic stimulation.
Gradient gel electrophoresis-immunoblot analysis (GGEI): a sensitive method for apolipoprotein profile determinations. (1987)

A method is described which will determine the distribution of individual apolipoproteins within the HDL subclasses. This method requires 1-2 microliters of plasma per determination and involves six steps: 1) electrophoresis of samples on non-denaturing 2-30% concave acrylamide gradient gels; 2) electrophoretic transfer of the lipoproteins to charge-modified nylon membranes; 3) fixation of the transferred lipoproteins with glutaraldehyde; 4) immunolocalization of the apolipoproteins with iodinated monospecific antibodies; 5) autoradiography followed by densitometry; and 6) reduction of the data to provide a plot of percent distribution versus particle size. When this method was applied to the analysis of rat apolipoproteins, differences were noted in the distribution of apoA-I, apoA-IV, and apoE. The majority of apoA-I was localized to HDL particles between 9 and 12 nm in diameter, with a median diameter of 10.0 nm, while apoE resided on substantially larger particles with a median diameter of 12.5 nm. ApoA-IV could be localized to three distinct areas: an HDL particle with a median diameter approximately 0.4 nm larger than apoA-I HDL, a particle smaller than albumin (lipoprotein-free apoA-IV), and a particle of 7.6 nm that does not appear to contain apoA-I or apoE.