gebhart/patrepeval huggingface dataset:
VO2 slow component correlates with vastus lateralis de-oxygenation and blood lactate accumulation during running. (2001)

In conclusion, the results of the present study support our hypothesis that the vastus lateralis de-oxygenation contributes consistently to the VO2 slow component development in running.
Effect of Prolactin on LH Receptor in Rat Luteal Cells (1976)

This investigation was undertaken to determine whether prolactin might act as a luteotropic hormone in the rat by increasing the receptor for LH. Immature female rats were treated with 5 SC injections of oFSH beginning at 0900 h on day 25; luteinization was induced with a single SC injection of oLH at 1500 h on day 27. In this model, LH-receptor activity, assessed by specific binding of [125I]iodohCG to ovarian membrane fractions, increased steadily (greater than 7-fold) from day 27 to day 33; specific [125I]iodoprolactin binding rose greater than 3-fold between days 27 and 31. Serum progesterone measured at 1500 h rose from greater than 10 ng/ml on day 27 to greater than 130 ng/ml on day 34. 2-Bromo-alpha-ergocryptine (CB-154, [EC]; 35 mug) given 2 X/day beginning at the time of LH injection, blocked nocturnal increases in serum prolactin measured at 0200 h on days 29, 30, and 31, and resulted in reduced binding of [125I]iodohCG on days 31 and 33; serum progesterone was similarly reduced on days 31 and 34 in EC-treated rats. Simultaneous treatment with EC and prolactin completely reversed the effects of EC with regard to both binding of [125A]iodohCG and serum progesterone. Changes in ovarian uptake of [125I]iodohCG in vivo were similar to those of the in vitro experiments described above. EC and/or prolactin treatment did not affect binding of [125I]iodoprolactin. In summary, the data indicate that LH in the absence of prolactin can induce the formation of corpora lutea which have an increased number of prolactin receptors but which have a few LH receptors and a reduced capacity to produce progesterone. If prolactin is present during the early luteinization process, corpora lutea develop an increased capacity to bind LH and to produce progesterone. It is possible that the increase in LH-receptor and progesterone production occur as independent events both mediated by the luteotropic action of prolactin. Alternatively, LH receptor might be limiting for LH stimulation of progesterone production.
Characterization of a new human apolipoprotein A-I Yame by direct sequencing of polymerase chain reaction-amplified DNA. (1991)

A new genetic variant apolipoprotein (apo), A-I Yame, was discovered during screening for apoA-I genetic variants with isoelectric focusing gel electrophoresis. To investigate the structural abnormality of apoA-I Yame, we amplified the apoA-I gene isolated from the proband's peripheral blood leukocytes with the polymerase chain reaction (PCR) method and directly sequenced these PCR fragments. ApoA-I Yame was found to have aspartic acid (GAC) substituted by tyrosine (TAC) at residue 13. We also identified this substitution by an automated DNA sequencer. This substitution was confirmed with amino acid sequencing of the isolated apoA-I Yame by Immobiline gel electrophoresis. This combined method, direct PCR from genomic DNA-derived individual peripheral blood leukocytes and subsequent direct sequencing, can be used to identify the entire sequence of apoA-I in a short period of time. Furthermore, with this method, it is possible to identify both alleles in heterozygous individuals.
Alkali metal ion assisted synthesis of faceted anatase TiO2 (2013)

This work reports on a simple hydrothermal method for tuning the shape and exposed face of TiO2 nanocrystal by using sodium titanate as a precursor in the presence of different alkali metal ion salts. The {101}-exposed anatase TiO2 was synthesized in lithium salt solution. The formation of anatase TiO2 with exposed high-index {301} facet, obtained in the presence of sodium ions, has never before been reported upon. When the reaction proceeded in potassium salt solution, the obtained anatase TiO2 with a high aspect ratio was elongated in the <001> direction. Anatase TiO2 with a high aspect ratio was obtained in hydrothermal process in the presence of low charge density high atomic number alkali metal ions, which were not easily absorbed by the {001} planes of anatase, so the growth along this direction was not restrained. The photodegradation of methylene blue, assisted by anatase TiO2 with various exposed faces reveals that the photoactivity of anatase {101} planes is larger than that of {301} planes.
Stabilization of Cu(0)-nanoparticles into the nanopores of modified montmorillonite: An implication on the catalytic approach for “Click” reaction between azides and terminal alkynes (2011)

In situ generation of Cu(0)-nanoparticles in the nanopores of modified montmorillonite and their catalytic activity in 1,3-dipolar cycloaddition reactions between azides and terminal alkynes to synthesise 1,2,3-triazoles have been carried out. The modification of montmorillonite was carried out by activation with H2SO4 under controlled conditions for generating nanopores to act as a “host” for the Cu(0)-nanoparticles, which is executed by successful loading of Cu(CH3COO)2 metal precursor through an incipient wetness impregnation technique followed by reduction with NaBH4. A TEM study reveals that Cu(0)-nanoparticles within the size range of 0–10 nm are evenly distributed on the support. The synthesized Cu(0)-nanoparticles exhibit face centered cubic (fcc) lattice geometry and serve as an efficient green catalyst for the “Click” azide–alkyne cycloaddition to afford highly regioselective 1,4-disubstituted 1,2,3-triazoles with excellent yields and selectivity in aqueous medium. The nanocatalysts can be recycled and reused several times without significant loss of their catalytic activity.
Random Reorganization of Molecular Weight Distribution in Linear Condensation Polymers<sup>1</sup> (1942)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRandom Reorganization of Molecular Weight Distribution in Linear Condensation Polymers1Paul J. FloryCite this: J. Am. Chem. Soc. 1942, 64, 9, 2205–2212Publication Date (Print):September 1, 1942Publication History Published online1 May 2002Published inissue 1 September 1942https://pubs.acs.org/doi/10.1021/ja01261a049https://doi.org/10.1021/ja01261a049research-articleACS PublicationsRequest reuse permissionsArticle Views446Altmetric-Citations121LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Enhancement of Nitrosourea Activity in Medulloblastoma and Glioblastoma Multiforme (1992)

We recommend comprehensive clinical toxicologic evaluation of combination therapy with O6-benzylguanine plus BCNU, which would allow subsequent design of phase I clinical trials.
The Clinical Importance of Nephron Mass (2010)

Abundant evidence supports the association between low birth weight (LBW) and renal dysfunction in humans. Anatomic measurements of infants, children, and adults show significant inverse correlation between LBW and nephron number. Nephron numbers are also lower in individuals with hypertension compared with normotension among white and Australian Aboriginal populations. The relationship between nephron number and hypertension among black individuals is still unclear, although the high incidence of LBW predicts low nephron number in this population as well. LBW, a surrogate for low nephron number, also associates with increasing BP from childhood to adulthood and increasing risk for chronic kidney disease in later life. Because nephron numbers can be counted only postmortem, surrogate markers such as birth weight, prematurity, adult height, reduced renal size, and glomerulomegaly are potentially useful for risk stratification, for example, during living-donor assessment. Because early postnatal growth also affects subsequent risk for higher BP or reduced renal function, postnatal nutrition, a potentially modifiable factor, in addition to intrauterine effects, has significant influence on long-term cardiovascular and renal health.
Effective source size, yield and beam profile from multi-layered bremsstrahlung targets (1996)

Modern conformal radiotherapy benefits from heterogeneous dose delivery using scanned narrow bremsstrahlung beams of high energy in combination with dynamic double focused multi-leaf collimation and purging magnets. When using a purging magnet to remove electrons and positrons the target space is limited and unorthodox thin multi-layered targets are needed. A computational technique has therefore been developed to determine the forward yield and the angular distributions of the bremsstrahlung beam as well as the size and location of the effective and the virtual photon point source for arbitrary multi-layer bremsstrahlung targets. The Gaussian approximation of the diffusion equation for the electrons has been used and convolved with the bremsstrahlung production process. For electrons with arbitrary emittance impinging on targets of any multi-layer and atomic number combination, the model is well applicable, at least for energies in the range 1-100 MeV. The intrinsic bremsstrahlung photon profile has been determined accurately by deconvolving the electron multiple scattering process from thin experimental beryllium target profiles. For electron pencil beams incident on a target of high density and atomic number such as tungsten, the size of the effective photon source stays at around a tenth of a millimetre. The effective photon source for low-Z materials such as Be, C and Al is located at depths from 3-7 mm in the target, decreasing with increasing atomic number. The effective photon source at off-axis positions then moves out considerably from the central axis, which should be considered when aligning collimators. For high-Z materials such as tungsten, the location of the effective photon source is at a few tenths of a millimetre deep. The virtual photon point source is located only a few tenths of a millimetre upstream of the effective photon source both for high- and low-Z materials. For 50 MeV electrons incident on multi-layered full range targets the radial energy fluence distributions will have a full width at half maximum (FWHM) of 80 to 100 mm at 1 m from the target. The best target composition made of two layers when the space is limited to 15 mm was found to be 9 mm-Be followed by 6 mm W. A thin beryllium target (approximately 3 mm) results in a high-intensity bremsstrahlung lobe with a FWHM of about 35 mm at the isocentre. Interestingly, the forward dose rate in such a beam is as high as 62% of the maximum achievable with an optimal target design, even if on average only 1 MeV is lost by the electrons.
The Use of Dielectric Lenses in Reflection Measurements (1953)

In order to minimize the effects of Presuel diffraction due to short range in the measurement of radar cross sections, a dielectric lens of low dielectric constant was introduced. The lens action was investigated by direct measurement of the shape of the incident phase front at the target, both with the lens in place and without it. The result of the phase measurement showed a reduction of phase variation over the exit aperture of the lens from 150 to 33°. In addition to the measurement of phase, the radar cross section of each of a set of metal cylinders was measured both with and without the lens, for comparison. The measured broadside radar cross section of a cylinder of length equal to about 80 per cent of the lens diameter was doubled by the addition of the lens. Calculation showed that the lens effectively eliminated phase error and that the residual error in measured results was essentially all due to anisotropy of the antenna of the simulated radar system used for the measurements.
Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras. (1994)

Recently, it has been suggested that abrogation of the wild type p53 protein function may alter the cellular response to DNA damaging agents, including ionizing radiation. This study was designed to compre the relative radiosensitivity and tumorigenicity of rat embryo fibroblast (REF) cell lines transfected with a mutant form of the p53 gene (plasmid MTp53pro193), alone, or in combination, with the H-ras (plasmid pEJ6.6) and HPV16-E7 (plasmid pJ4 omega 16.E7) oncogenes. Transfection of the mutant p53pro193 gene alone resulted in selected clones having increased radioresistance in culture which correlated with increased mutant p53 expression in these clones. However, the co-transfection of mutant p53 and H-ras genes or triple transfection of mutant p53, H-ras and E7 genes resulted in clones with high mutant p53 expression, significantly increased radioresistance and uniform tumorigenicity. There was no correlation between intrinsic radioresistance and spontaneous metastasis in the tumorigenic REF transfectant clones. Stepwise acquisition of radioresistance and an aggressive tumor cell phenotype is observed when the mutant p53 gene and HPV E7 co-operate with the ras oncogene in transfection assays, and can be correlated to increases in mutant p53 expression.
Blooming space (2011)

In this paper, we propose the concept of a fusion between flower arrangement and interactive artwork. We create a prototype of a light wall sculpture whose surface's color changes according to the flower's color detected by a vase-shaped device. The color information is translated through wireless communication between the vase and the sculpture to create an illusion that the arranged flower itself changes the light condition of the space. We made an art installation "blooming space" composed of the vase and the light wall sculpture.
Dilute Trichloroethylene Decomposition in Air by the Non-Thermal Plasma Process Combined with the Manganese Oxide (2005)

Abstract The non-thermal plasma is a very effective technique to decompose various kinds of gaseous organic compounds. The trichloroethylene (TCE) is one of the effective washing reagents to remove oily liquid materials or similar fatty materials from the solid surface but is harmful for human beings as the carcinogenic materials. The authors have been engaged in developing the non-thermal plasma technology to decompose that TCE efficiently. During the research on how to improve the decomposition efficiency of TCE, we found that the ozone generated in the air by the plasma can decompose TCE which is named as Indirect Process, comparing with the conventional plasma process named as Direct Process. We found that manganese oxide catalyst which can easily decompose the ozone and may generate oxygen radicals. The manganese oxide can improve the TCE decomposition efficiency, 20 or 80%, for Direct or Indirect Processes.
Modeling of acetylcholinesterase inhibition by tacrine analogues using Bayesian-regularized Genetic Neural Networks and ensemble averaging (2006)

Acetylcholinesterase inhibition was modeled for a set of 136 tacrine analogues using Bayesian-regularized Genetic Neural Networks (BRGNNs). In the BRGNN approach the Bayesian-regularization avoids overtraining/overfitting and the genetic algorithm (GA) allows exploring an ample pool of 3D-descriptors. The predictive capacity of our selected model was evaluated by averaging multiple validation sets generated as members of diverse-training set neural network ensembles (NNEs). The ensemble averaging provides reliable statistics. When 40 members are assembled, the NNE provides a reliable measure of training and test set R values of 0.921 and 0.851 respectively. In other respects, the ability of the nonlinear selected GA space for differentiating the data was evidenced when the total data set was well distributed in a Kohonen Self-Organizing Map (SOM). The location of the inhibitors in the map facilitates the analysis of the connection between compounds and serves as a useful tool for qualitative predictions.
The β-Lacta Test for Direct Detection of Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in Urine (2014)

With the β-Lacta test, production of extended-spectrum β-lactamases (ESBLs) was assayed in 200 urine samples showing Gram-negative bacilli during direct microscopic examination. While 168 samples tested negative, all samples yielding ESBL-producing Enterobacteriaceae after culture gave positive (n = 30) or uninterpretable (n = 2) results. The sensitivity and specificity of ESBL detection were 94% and 100%, respectively.
Acid hypersensitivity in patients with eosinophilic oesophagitis (2009)

Patients with eosinophilic oesophagitis are hypersensitive to acid perfused in the oesophagus, and pathophysiologic findings are likely confined to the peripheral tissue. Reflux from physiological acid may play a role in the symptoms of eosinophilic oesophagitis.
Structure of an immunoglobulin Fab fragment specific for poly(dG).poly(dC). (1994)

Jel 72 is a murine monoclonal antibody that is highly specific for the right-handed DNA duplex formed by poly(dG).poly(dC). The three-dimensional structure of the antigen-binding fragment (Fab) of Jel 72 has been determined by x-ray crystallographic methods and refined to 2.7-A resolution. The structure has been determined using a combination of molecular replacement and multiple isomorphous replacement techniques. Crystals of Jel 72 contain two Fab fragments/asymmetric unit. The orientation of each of the four separate constant and variable domain pairs was determined from rotation function searches against appropriately oriented model Fab fragments. The rotated Fab domain pairs were placed within the unit cell using a phased translation search procedure with low resolution phases calculated from three derivatives. The two crystallographically independent Fab fragments possess "elbow" angles (relating the variable and constant domain pairs) that differ by 14 degrees (146 degrees versus 132 degrees). The shape and electrostatic surface potential of the combining site suggest a possible model for the recognition of double helical DNA. The model proposes that residues in the third hypervariable region of the heavy chain interact with the DNA bases via the major groove of poly(dG).poly(dC). This model may be applicable to the recognition of double-stranded DNA by autoimmune antibodies that occur in systemic lupus erythematosus.
On-chip learning in pulsed silicon neural networks (2002)

Self-learning chips to implement conventional ANN (artificial neural network) algorithms are very difficult to design and unconvincing in their results. We explain why this is so and say what lessons previous work teaches us in the design of self-learning systems. We offer an alternative, 'biologically-inspired' approach, explaining what we mean by this term and providing an example of a robust, self-learning design which can solve simple classical-conditioning tasks.
Gate breakdown in MESFETs and HEMTs (1991)

A new model for gate breakdown in MESFETs and HEMTs is presented. The model is based upon a combination of thermally assisted tunneling and avalanche breakdown. When thermal effects are considered it is demonstrated that the model predicts increasing drain-source breakdown as the gate electrode is biased towards pinch-off, in agreement with experimental data. The model also predicts the gate current versus bias behavior observed in experimental data. The model is consistent with various reports of breakdown and light emission phenomena reported in the literature.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Intraarray statics and phase corrections obtained by beamforming in the short-time Fourier transform domain: Application to supergrouping (2017)

We present a method to correct for intra-array statics and phase variations pre-stack trace ensembles intended for local summation. We apply the proposed approach as an additional step before summing traces via supergouping. Corrections are derived from beamforming techniques applied in the short-time Fourier transform (STFT) domain performed independently for each frequency component. Beamforming allows to handle more complex variations of recorded signals than simple relative time shifts from trace to trace. Phase correction weights are calculated using SVD of the data matrix in the STFT domain. The proposed approach is demonstrated on synthetic and complex 3D land data from Saudi Arabia. Presentation Date: Thursday, September 28, 2017 Start Time: 9:45 AM Location: 360A Presentation Type: ORAL
Capacity-based cost modeling for light rail and bus rapid transit systems (2005)

Choosing between Light Rail Transit (LRT) and Bus Rapid Transit (BRT) systems is often controversial and not an easy task for transportation planners who are contemplating the upgrade of their public transportation services. These two transit systems provide comparable services for medium-sized cities from the suburban neighborhood to the Central Business District (CBD) and utilize similar right-of-way (ROW) categories. The research is aimed at developing a method to assist transportation planners and decision makers in determining the most feasible system between LRT and BRT. Cost estimation is a major factor when evaluating a transit system. Typically, LRT is more expensive to build and implement than BRT, but has significantly lower Operating and Maintenance (OM) costs than BRT. This dissertation examines the factors impacting capacity and costs, and develops cost models, which are a capacity-based cost estimate for the LRT and BRT systems. Various ROW categories and alignment configurations of the systems are also considered in the developed cost models. Kikuchi's fleet size model (1985) and cost allocation method are used to develop the cost models to estimate the capacity and costs. The comparison between LRT and BRT are complicated due to many possible transportation planning and operation scenarios. In the end, a user-friendly computer interface integrated with the established capacity-based cost models, the LRT and BRT Cost Estimator (LBCostor), was developed by using Microsoft Visual Basic language to facilitate the process and will guide the users throughout the comparison operations. The cost models and the LBCostor can be used to analyze transit volumes, alignments, ROW configurations, number of stops and stations, headway, size of vehicle, and traffic signal timing at the intersections. The planners can make the necessary changes and adjustments depending on their operating practices.
Migration-enhanced epitaxy of GaAs and AlGaAs (1993)

The principle and characteristics of migration-enhanced epitaxy are reviewed. Migration of surface adatoms along the surface is very important for growing high quality layers and atomically flat heterojunctions. In the migration-enhanced epitaxy of GaAs and AlGaAs, migration of surface Ga and Al atoms is enhanced even at low substrate temperatures by evaporating them onto a clean GaAs surface under an As-free or low As pressure atmosphere. Thus, high quality GaAs and AlGaAs layers and flat heterojunctions have been grown by this method. Migration-enhanced epitaxy has also proved useful in investigating atomic processes during epitaxial growth.