gebhart/patrepeval huggingface dataset:
Intercalation of montmorillonite with individual chromium(III) hydrolytic oligomers (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntercalation of montmorillonite with individual chromium(III) hydrolytic oligomersA. Drljaca, J. R. Anderson, L. Spiccia, and T. W. TurneyCite this: Inorg. Chem. 1992, 31, 23, 4894–4897Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/ic00049a033https://doi.org/10.1021/ic00049a033research-articleACS PublicationsRequest reuse permissionsArticle Views91Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Human mononuclear cell modulation of endothelial cell proliferation. (1983)

Endothelial cell proliferation is a histologic characteristic of several forms of nephritis characterized by infiltration of the glomerulus with mononuclear cells. To investigate the mechanism mediating this event, human endothelial cells isolated from umbilical veins and cultured in vitro were incubated with supernatants of cultured human mononuclear cells. Supernatants from mononuclear cells exerted a dose-dependent stimulatory effect on endothelial cell proliferation. The stimulatory effect of supernatant was almost entirely removed by prior depletion of mononuclear cells of monocytes by adherence, suggesting that a monocyte product was responsible for the activity. To investigate the nature of the ligand responsible, partially purified human interleukin I added to endothelial cell cultures was found to stimulate cellular proliferation.
Prognostic role of matrix metalloproteinases in bladder carcinoma: a systematic review and meta-analysis (2017)

Recent studies have shown that matrix metalloproteinases (MMPs) might be a biomarker for predicting outcomes of bladder cancer. However, the prognostic value of overexpression of MMPs in bladder cancer is debatable and the studies are inconsistent. Therefore, this meta-analysis was performed to clarify the specific association and prognostic value of overexpression of MMPs in bladder carcinoma. Relevant studies were identified by searching PubMed, EMBASE, and the Web of Science. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) for disease-specific survival (DSS), overall survival (OS), disease/recurrence-free survival (DFS/RFS), and progression/metastasis-free survival (PFS/MFS) were analyzed to determine the prognostic value of MMPs. In total, eighteen applicable studies were included in this meta-analysis. We found that high expression of MMPs significantly correlated with a poor DSS and OS (HR=1.66; 95% CI = 1.38-2.01 and HR= 1.67; 95%CI= 1.26-2.22). MMPs also predicted tumor progression and metastasis with a pooled HR of 3.03 (95% CI 1.98-4.64). However, high MMPs expression had no pivotal impact on DFS/RFS (HR= 1.21; 95% CI= 0.96-1.53). With the purpose of better understanding the prognostic role of MMPs in patients wirh bladder carcinoma, we carried out this systematic review and meta-analysis.
Gene transfer of wild-type p53 results in restoration of tumor-suppressor function in a medulloblastoma cell line (1995)

The replacement of functional genes into cells that lack genes or have mutant genes is the basis of gene therapy. In cancer, where cells often have multiple genetic defects, the replacement of critical genes may suffice to suppress cell growth or induce cell death. The high frequency of mutations of the p53 tumor-suppressor gene in human cancers, including primary brain tumors, suggests that p53 plays a critical role in carcinogenesis and tumor progression. We report the successful transfer of the wild-type p53 gene using a defective herpes simplex viral vector into a human medulloblastoma cell line containing a mutant copy of p53. Upon gene transfer, we detected novel expression of wild-type p53 protein in the cells. In addition, the p53 protein was functionally active, since gene transfer resulted in increased levels of mdm2 proteins and induced cell cycle arrest of the majority of transduced cells. To our knowledge, this is the first report of the use of this vector system to carry wild-type p53. We conclude that defective herpes simplex viral vectors can transfer and express p53 in human primary brain tumor cells in vitro, restoring wild-type p53 tumor-suppressor functions.
Nano-Gold Catalysis in Fine Chemical Synthesis (2011)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTNano-Gold Catalysis in Fine Chemical SynthesisYan Zhang†, Xinjiang Cui†‡, Feng Shi*†, and Youquan Deng†View Author Information† Centre for Green Chemistry and Catalysis, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China‡ Graduate School of the Chinese Academy of Sciences, Beijing, 100049, China*E-mail: [email protected]Cite this: Chem. Rev. 2012, 112, 4, 2467–2505Publication Date (Web):November 23, 2011Publication History Received12 July 2011Published online23 November 2011Published inissue 11 April 2012https://pubs.acs.org/doi/10.1021/cr200260mhttps://doi.org/10.1021/cr200260mreview-articleACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views19417Altmetric-Citations610LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alcohols,Catalysts,Gold,Oxidation,Selectivity Get e-Alerts
Determination of brain and plasma drug concentrations by liquid chromatography/tandem mass spectrometry (2000)

A method is described for the evaluation of drug concentrations in plasma and brain from treated rats. The analyte is recovered from plasma or brain homogenate by liquid-liquid extraction and subsequently analyzed by liquid chromatography/tandem mass spectrometry (LC/MS/MS). A simple experimental protocol renders the procedure valuable for obtaining information rapidly on brain penetration and plasma exposure of specific classes of compounds. This methodology has been applied to evaluate brain penetration with 30 different compounds from the same discovery program. In an attempt to increase throughput in our screening efforts, mixture dosing was evaluated. Results from single compound administration were compared with results following administration of a mixture of four compounds. Preliminary results, with specific classes of compounds, show no major differences (ranking order) in brain or plasma concentrations between mixture dosing and single compound administration, suggesting that mixture dosing could be applicable to brain penetration studies in the drug discovery phase.
A wavelet transform approach to texture analysis (1992)

Traditional texture analysis algorithms focus too much on the local coupling between image pixels. Time/frequency analytical tools such as the Gabor and wavelet transforms can efficiently characterize the coupling of different scales in textures, and help to overcome this difficulty. However, the conventional wavelet transform, which has a finer resolution in the lower frequency channels, does not work properly for textured images, since textures are quasi-periodic signals whose dominant frequencies are located in the middle frequency regions. In the present research, a tree-structured wavelet transform is proposed. An adaptive procedure is developed to zoom into any frequency channels with significant information so that the decomposition can be further performed. The application of the new transform to texture classification is demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Feminist Biblical Hermeneutics: A Failure of Theoretical Nerve (1998)

Journal Article Feminist Biblical Hermeneutics: A Failure of Theoretical Nerve Get access J. D. H. Amador J. D. H. Amador Adjunct faculty member in the Department of Humanities and Religion at Santa Rosa Junior College, Santa Rosa, CA 95403 Search for other works by this author on: Oxford Academic Google Scholar Journal of the American Academy of Religion, Volume 66, Issue 1, Spring 1998, Pages 39–57, https://doi.org/10.1093/jaarel/66.1.39 Published: 01 March 1998
Fabrication of SnS quantum dots for solar cell applications: issues of capping and doping (2014)

We present our recent study of SnS particles in the backdrop of significant developments that have taken place so far for which a review of the present status of this material, its structural, optical, electronic characteristics, and device performance is described. To further improve the performance of low-cost chalcogenide-based solar cells, we propose to employ a third-generation solar cells fabrication scheme, where an intermediate bandgap layer can be incorporated in a CIS solar cell to increase its current generation and efficiency. For this purpose SnS quantum dots (QD) embedded indium sulfide (In2S3) layer is developed. We address how to cap the QD surface for defect passivation and protection from ambient and the doping nature of the particles.
A voice activity detector based on cepstral analysis (1993)

This paper proposes a new approach to speech end-point detection based on cepstral analysis. The algorithm is based on explicit (static) modelling of speech and non-speech, and decisions are made on each incoming (overlapped) cepstral frame, according to model similarity scores. The cepstral analysis provides excellent levelindependence, meaning that parameter adjustment, decision thresholds etc, are unnecessary. A high degree of robustness to additive noise is demonstrated, even though the models are static. Accurate end-points are recovered with SNR levels of 0dB. Keywords: speech analysis, end-point detection, voice activity detection, robustness. 1 INTRODUCTION Many early voice-activity-detection (VAD) algorithms were based on a combination of shortterm energy and zero-crossing-rate (ZCR) measurements, [1], [2] and [3]. Such algorithms detect speech by relying on the fact that an increase in energy is likely to occur somewhere between the two ends of a word or `talkspurt&apos;. Havi...
FOUNDATION ANALYSIS AND DESIGN. FOURTH EDITION (1988)

The fourth edition of this textbook has been rewritten and provides state-of-the-art (soa) and state-of-practice (sop) methods in foundation engineering. This edition places emphasis on computer methods and finite element methods (fem), involving matrix methods, to reflect the use of the pc and fem techniques. The following chapters are presented: (1) introduction; (2) geotechnical properties; laboratory testing index settlement and strength correlations; (3) exploration, sampling and in-situ soil measurements; (4) bearing capacity of foundations; (5) foundation settlements; (6) improving site soils for foundation use; (7) factors to consider in foundation design; (8) spread footing design; (9) special footings and beams on elastic foundations; (10) mat foundations; (11) lateral earth pressure; (12) mechanically stabilized earth and concrete retaining walls; (13) sheet-pile walls - cantilevered and anchored; (14) braced, tieback and slurry walls for excavations; (15) cellular cofferdams; (16) single piles -static capacity; (17) single piles -dynamic analysis; (18) pile foundations -groups; (19) drilled piers or caissons; (20) design of foundations for vibration control.
A comparison of EPA screening measurements and annual 222Rn concentrations in statewide surveys. (1990)

Variations in indoor Rn make it difficult to assess an individual's long-term exposure based on sampling surveys that are quite limited in time and number. The present work compares the results of short-term and long-term statewide surveys conducted in a region that contains average-strength Rn sources, energy-efficient housing, and both extremely cold and hot seasons
Pathogenesis of Murine Experimental Allergic Rhinitis: A Study of Local and Systemic Consequences of IL-5 Deficiency (2002)

Recent studies have demonstrated an important role for IL-5-dependent bone marrow eosinophil progenitors in allergic inflammation. However, studies using anti-IL-5 mAbs in human asthmatics have failed to suppress lower airway hyperresponsiveness despite suppression of eosinophilia; therefore, it is critical to examine the role of IL-5 and bone marrow responses in the pathogenesis of allergic airway disease. To do this, we studied the effects of IL-5 deficiency (IL-5(-/-)) on bone marrow function as well as clinical and local events, using an established experimental murine model of allergic rhinitis. Age-matched IL-5(+/+) and IL-5(-/-) BALB/c mice were sensitized to OVA followed by 2 wk of daily OVA intranasal challenge. IL-5(-/-) OVA-sensitized mice had significantly higher nasal mucosal CD4(+) cells and basophilic cell counts as well as nasal symptoms and histamine hyperresponsiveness than the nonsensitized group; however, there was no eosinophilia in either nasal mucosa or bone marrow; significantly lower numbers of eosinophil/basophil CFU and maturing CFU eosinophils in the presence of recombinant mouse IL-5 in vitro; and significantly lower expression of IL-5Ralpha on bone marrow CD34(+)CD45(+) progenitor cells in IL-5(-/-) mice. These findings suggest that IL-5 is required for normal bone marrow eosinophilopoiesis, in response to specific Ag sensitization, during the development of experimental allergic rhinitis. However, the results also suggest that suppression of the IL-5-eosinophil pathway in this model of allergic rhinitis may not completely suppress clinical symptoms or nasal histamine hyperresponsiveness, because of the existence of other cytokine-progenitor pathways that may induce and maintain the presence of other inflammatory cell populations.
High-precision determination of the light-quark masses from realistic lattice QCD (2006)

Three-flavor lattice QCD simulations and two-loop perturbation theory are used to make the most precise determination to date of the strange-, up-, and down-quark masses, ${m}_{s}$, ${m}_{u}$, and ${m}_{d}$, respectively. Perturbative matching is required in order to connect the lattice-regularized bare-quark masses to the masses as defined in the $\overline{\mathrm{MS}}$ scheme, and this is done here for the first time at next-to-next-to leading (or two-loop) order. The bare-quark masses required as input come from simulations by the MILC collaboration using so-called staggered quarks, with three flavors of light quarks in the Dirac sea; these simulations were previously analyzed in a joint study by the HPQCD and MILC collaborations, using degenerate $u$ and $d$ quarks, with masses as low as ${m}_{s}/8$, and two values of the lattice spacing, with chiral extrapolation/interpolation to the physical masses. With the new perturbation theory presented here, the resulting $\overline{\mathrm{MS}}$ masses are ${m}_{s}^{\overline{\mathrm{MS}}}(2\text{ }\text{ }\mathrm{GeV})=87(0)(4)(4)(0)\text{ }\text{ }\mathrm{MeV}$, and ${\stackrel{^}{m}}^{\overline{\mathrm{MS}}}(2\text{ }\text{ }\mathrm{GeV})=3.2(0)(2)(2)(0)\text{ }\text{ }\mathrm{MeV}$, where $\stackrel{^}{m}=\frac{1}{2}({m}_{u}+{m}_{d})$ is the average of the $u$ and $d$ masses. The respective uncertainties are from statistics, simulation systematics, perturbation theory, and electromagnetic/isospin effects. The perturbative errors are about a factor of 2 smaller than in an earlier study using only one-loop perturbation theory. Using a recent determination of the ratio ${m}_{u}/{m}_{d}=0.43(0)(1)(0)(8)$ due to the MILC collaboration, these results also imply ${m}_{u}^{\overline{\mathrm{MS}}}(2\text{ }\text{ }\mathrm{GeV})=1.9(0)(1)(1)(2)\text{ }\text{ }\mathrm{MeV}$ and ${m}_{d}^{\overline{\mathrm{MS}}}(2\text{ }\text{ }\mathrm{GeV})=4.4(0)(2)(2)(2)\text{ }\text{ }\mathrm{MeV}$. A technique for estimating the next order in the perturbative expansion is also presented, which uses input from simulations at more than one lattice spacing; this method is used here in the estimate of the systematic uncertainties.
Insecticidal and Ovicidal Effects of the Seed Extract of Atriplex Canescens against Culex Quinquefasciatus (1998)

The seed extract of the saltbrush Atriplex canescens (Forssk.) A. Nutt. was tested for insecticidal and ovicidal activity against the mosquito Culex quinquefasciatus Say. The exposure of early fourth instar mosquito larvae to a series of aliquots of the seed extract revealed a significant larval and adult mortality at 0.1–1000 ppm. Seed extract also demonstrated some ovipositional deterrence and ovicidal activity against C. quinquefasciatus.
Dendritic cells exposed to extracellular adenosine triphosphate acquire the migratory properties of mature cells and show a reduced capacity to attract type 1 T lymphocytes (2002)

We previously reported that chronic stimulation with low, noncytotoxic doses of extracellular adenosine triphosphate (ATP) induced a distorted maturation of dendritic cells (DCs) and impaired their capacity to initiate T-helper (Th) 1 responses in vitro. Here, we examined the effects of ATP on chemokine-receptor expression and chemokine production by DCs. ATP strongly induced expression of CXC chemokine receptor 4 on both immature and lipopolysaccharide (LPS)-stimulated DCs and slightly up-regulated CC chemokine receptor (CCR) 7 on both DC types. In contrast, ATP reduced CCR5 expression on immature DCs. These effects were confirmed at both the messenger RNA and protein levels and were not produced by uridine triphosphate (UTP). Consistent with the changed receptor expression, ATP increased migration and intracellular calcium of immature and mature DCs to stromal-derived factor 1 (CXC ligand [CXCL] 12) and macrophage inflammatory protein [MIP] 3 beta (CC ligand [CCL] 19), whereas responses to MIP-1 beta (CCL4) were reduced. DCs are an important source of chemokines influencing recruitment of distinct T-lymphocyte subsets. ATP, but not UTP, significantly reduced LPS-induced production of interferon-inducible protein 10 (CXCL10) and regulated upon activation, normal T-cell expressed and secreted chemokine (CCL5); increased secretion of macrophage-derived chemokine (CCL22); and did not change production of thymus and activation-regulated chemokine (CCL17). Consistent with these findings, supernatants from ATP-treated mature DCs attracted Th1 and T-cytotoxic 1 cells less efficiently, whereas migration of Th2 and T cytotoxic 2 cells was not affected. Our data suggest that ATP provides a signal for enhanced lymph node localization of DCs but that it may, at the same time, diminish the capacity of DCs to amplify type 1 immune responses.
Ultrasound Flow Sensor Based on Arrays of Piezoelectric Transducers Integrated in a Composite (2013)

The functionalization of fiber-reinforced polymer composites by integration of piezoelectric transducers allows for both the measurement and the excitation of guided waves within the component. A common use for guided waves in composite components is nondestructive examination. In the presented work, however, the radiation of ultrasound waves from the surface of the component due to guided waves in the component is utilized. Glass fiber-reinforced polypropylene (GF/PP) plates with integrated arrays of piezoelectric macro fiber composite (MFC) transducers are used as ultrasound transmitter and receiver. The plates are then set up as facing walls of a rectangular duct and the sound transit times between the plates are measured. From the measured sound transit times, the velocity of gas flow inside the composite duct is determined. In that way, a flow sensor integrated in the walls of a flow channel, e.g. an air duct, made of composites is built. This paper focuses on the manufacturing of such an integrated flow sensor.
Validity and Reliability of the US National Cancer Institute’s Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) (2015)

Evidence demonstrates favorable validity, reliability, and responsiveness of PRO-CTCAE in a large, heterogeneous US sample of patients undergoing cancer treatment. Studies evaluating other measurement properties of PRO-CTCAE are under way to inform further development of PRO-CTCAE and its inclusion in cancer trials.
Building Extraction Based on Hue Cluster Analysis in Complex Scene (2009)

This paper presents an approach to extract building region in an image with complex scene. The algorithm highlights the edge characteristics of the target in image pre-processing step, uses the improved Hough transform line detection algorithm and the line optimization algorithm to keep the effective straight-line segments. Then it clusters the dominant hues of each effective segment's surrounding area, which will be made statistical analysis to group the straight-lines with building hue and keep the building lines with consistent hue. Finally, the building region is gotten in original image by the effective lines. Our experiments on dozens of pictures by this method and two other building extraction methods, demonstrate that this method is not only good for extracting the covered buildings in complex scene images, but also good for locating the buildings submerged in the background accurately.