gebhart/patrepeval huggingface dataset:
La via della beatitudine e della rovina secondo il Salmo 1. (1986)

As a result of the antithetical and chiastic parallelism (a b b' a'), the figures of the righteous man and of the wicked man in Ps 1 illuminate each other reciprocally. Of the righteous man it is said that he prospers (verse 3), because he stands in a saving relationship to God (verses 1-2); of the wicked man, that he perishes, because he lives immersed in evil and totally separated from that which is good (verses 4-5). In his conclusion the Psalmist offers the theolofical reason for the prospering of the righteous (verse 6a) and for the ruin of the wicked (verse 6b).
The author highlights the typw of reading of Ps 1 that is found in Lk 21,36 and in Mt 7,13-14, and points out that in the liturgical context of the Church the horizon of this same Psalm is broadened and is charged with escatological and is charged with escatolofical and universal content.
Formation of Nanoparticles Assisted by Ionic Liquids (2012)

Abstract The sections in this article are Metal Nanoparticles in Ionic Liquids: Synthesis Reduction of Organometallic Precursors Decomposition of Organometallic Precursors Transfer from an Aqueous/Organic Phase to the Ionic Liquid Phase Bombardment of Bulk Materials Metal Nanoparticles in Ionic Liquids: Stabilization Metal Nanoparticles in Ionic Liquids: Recyclable Multiphase Catalyst‐Systems Hydrogenation of Multiple Bonds with Metal Nanoparticles in Ionic Liquids Carbon–Carbon Cross‐Coupling Reactions Catalyzed by Palladium Nanoparticles in Ionic Liquids Functionalization and Defunctionalization Reactions Using Metal Nanoparticles in Ionic Liquids Isotope Exchange Catalyzed by Metal Nanoparticles in Ionic Liquids Application of Metal Nanoparticle Catalysts in Ionic Liquids for Energy‐ and Environment‐Related Systems General Remarks
A CASE OF CYANOSIS DEMONSTRATING THE CIRCUMCORNEAL VEINS (1932)

As a teacher of ophthalmology to undergraduate students, I have always laid great stress on the recognition and clinical interpretation of circumcorneal injection. I am impelled, therefore, to present the appended case of engorgement of the circumcorneal vessels, which shows in a remarkable manner their anatomic distribution. Ordinarily it is the anterior ciliary arteries and their peripheral terminations, the circumcorneal loops of vessels, that are engorged. This is the case in all acute inflammatory conditions affecting the cornea, iris or ciliary body. In the case presented, the anterior ciliary veins were engorged, but as in this location the veins accompany the arteries, the study from an anatomic standpoint is not vitiated. In fact, it may be that it is enhanced, for in this instance the circumcorneal loops of vessels that spring from the anterior ciliary arteries just before they penetrate the sclera were not shown, but the emergence of
Atrial fibrillation-induced atrial contractile dysfunction: a tachycardiomyopathy of a different sort (2002)

AF-induced atrial contractile dysfunction is not due to beta-adrenergic desensitization or dysfunction of the sarcoplasmic reticulum and thus is based on different cellular mechanisms than a ventricular tachycardia-induced cardiomyopathy. Instead, downregulation or altered function of the L-type Ca(2+)-channel and an increased Ca(2+) extrusion via the Na(+)/Ca(2+)-exchanger seem to be responsible for the depressed contractility in remodeled atria.
Developing QR Code Based Augmented Reality Using SIFT Features (2012)

In this paper, we employ the widely used 2D barcode, the QR Code, to implement a QR Code based augmented reality (AR) system. In this system, QR Code is used to replace the traditional AR marker and the code can be tracked by the system without any maker registration procedure. This implies that the system is suitable for public domain applications since QR Code is a widely acceptable 2D barcode standard. Users can generate their codes and do not need to register the codes into the system. However, since every QR Code is different, to track the codes in a universal way a robust tracking technique needs to be applied. In this paper, we use the SIFT feature to enable QR Code tracking and also improve tracking accuracy and stability. We have developed this QR Code based AR system and its performance is encouraging. The code can be tracked efficiently with sufficient accuracy and stability.
Androgènes : l'autre façon de stimuler des follicules ovariens ? (2010)

La diminution precoce du statut folliculaire ovarien n'est pas une condition rare. Elle determine une baisse des chances de conception qui reste refractaire aux approches medicales actuelles. A la recherche d'alternatives therapeutiques, certains auteurs se sont interesses au role stimulateur probable des androgenes sur la folliculogenese. Chez le primate, un traitement androgenique a fortes doses entraine une augmentation de l'effectif des follicules en croissance ainsi que leur sensibilisation a la FSH. Chez la femme, le syndrome des ovaires polykystiques, certaines affections virilisantes, ou encore le modele des transsexuelles, constituent des exemples du lien probable entre androgenes et hyperfolliculogenese. Des essais d'augmentation du nombre de follicules et/ou de leur sensibilite a la FSH soit par l'administration systemique d'androgenes, soit par l'inhibition de leur metabolisme, ou encore par la stimulation de leur production thecale via l'activite LH ne semblent donner pour l'instant que des resultats mitiges. Cet article porte un regard objectif, aussi bien sur le rationnel des traitements androgeniques que sur les resultats des essais cliniques disponibles, afin de mieux entrevoir leur role reel dans l'arsenal therapeutique de demain.
Fast k-Nearest Neighbour Search via Prioritized DCI (2017)

Most exact methods for k-nearest neighbour search suffer from the curse of dimensionality; that is, their query times exhibit exponential dependence on either the ambient or the intrinsic dimensionality. Dynamic Continuous Indexing (DCI) offers a promising way of circumventing the curse and successfully reduces the dependence of query time on intrinsic dimensionality from exponential to sublinear. In this paper, we propose a variant of DCI, which we call Prioritized DCI, and show a remarkable improvement in the dependence of query time on intrinsic dimensionality. In particular, a linear increase in intrinsic dimensionality, or equivalently, an exponential increase in the number of points near a query, can be mostly counteracted with just a linear increase in space. We also demonstrate empirically that Prioritized DCI significantly outperforms prior methods. In particular, relative to Locality-Sensitive Hashing (LSH), Prioritized DCI reduces the number of distance evaluations by a factor of 14 to 116 and the memory consumption by a factor of 21.
IkeaBot: An autonomous multi-robot coordinated furniture assembly system (2013)

We present an automated assembly system that directs the actions of a team of heterogeneous robots in the completion of an assembly task. From an initial user-supplied geometric specification, the system applies reasoning about the geometry of individual parts in order to deduce how they fit together. The task is then automatically transformed to a symbolic description of the assembly-a sort of blueprint. A symbolic planner generates an assembly sequence that can be executed by a team of collaborating robots. Each robot fulfills one of two roles: parts delivery or parts assembly. The latter are equipped with specialized tools to aid in the assembly process. Additionally, the robots engage in coordinated co-manipulation of large, heavy assemblies. We provide details of an example furniture kit assembled by the system.
Slowing the growth of ice with synthetic macromolecules: beyond antifreeze(glyco) proteins (2010)

Biological antifreezes are a relatively large and diverse class of proteins (and very recently expanded to include lipopolysaccharides) which are capable of interacting with ice crystals in such a manner as to influence and, under the correct conditions, to prevent their growth. These properties allow for the survival of organisms which are either continuously or sporadically exposed to subzero temperatures which would otherwise lead to cryo-injury/death. These proteins have been found in a range of organisms, including plants, bacteria, insects and fish, and the proteins themselves have a diverse range of chemical structures ranging from the highly conserved antifreeze glycoproteins (AFGPs) to the more diverse antifreeze proteins AFPs. Their unique abilities to non-colligatively decrease the freezing point of aqueous solutions, inhibit ice recrystallisation and induce dynamic ice shaping suggest they will find many applications from cell/tissue/organ cryostorage, frozen food preservatives, texture enhancers or even as cryosurgery adjuvants. However, these applications have been limited by a lack of available material and also underlying questions regarding their mode of activity. The aim of this review article is to highlight the potential of polymeric materials to act as synthetic mimics of antifreeze(glyco) proteins, as well as to summarise the current general challenges in designing compounds capable of mimicking AF(G)Ps. This will cover the basic properties and modes of action of AF(G)Ps along with the methods commonly used to evaluate their activity. This section is essential to specifically define the ‘antifreeze’ terminology in terms of these proteins' unique function and to distinguish them from conventional antifreezes. A detailed evaluation of the processes involved in AF(G)P activity is beyond the scope of this review, but the reader will be pointed towards relevant literature. This will then be placed in the context of modern polymer science, with a focus on the ability of synthetic polymers to display some type of specific antifreeze activity, which will be summarised. Finally, the potential applications of these materials will be highlighted and future avenues for their research and the challenges faced in achieving these goals suggested.
Blind deconvolution of 3D transmitted light brightfield micrographs (2000)

The blind deconvolution algorithm for 3D transmitted light brightfield (TLB) microscopy, published previously [Holmes et al. Handbook of Biological Confocal Microscopy (1995)], is summarized with example images. The main emphasis of this paper is to discuss more thoroughly the importance and usefulness of this method and to provide more detailed evidence, some being quantitative, of its necessity. Samples of horseradish peroxidase (HRP)-stained pyramidal neurones were prepared and evaluated for the ability to see fine structures clearly, including the dendrites and spines. It is demonstrated that the appearance of fine spine structure, and means of identifying spine categories, is made possible by using blind deconvolution. A comparison of images of the same sample from reflected light confocal microscopy, which is the conventional light microscopic way of viewing the 3D structure of these HRP-stained samples, shows that the blind deconvolution method is far superior for clearly showing the structure with less distortion and better resolution of the spines. The main significance of this research is that it is now possible to obtain clear images of 3D structure by light microscopy of absorbing stains. This is important because the TLB microscope is probably the most widely used modality in the life-science laboratory, yet, until now, there has been no reliable means for it to provide visualization of 3D structure clearly. The main importance of the blind deconvolution approach is that it obviates the need to measure the point spread function of the optical system, so that it now becomes realistic to provide a 3D light microscopic deconvolution method that can be pervasively used by microscopists.
Speaker-independent phoneme recognition on TIMIT database using integrated time-delay neural networks (TDNNs) (1990)

A structure of neural networks (NNs) is described for speaker-independent and context-independent phoneme recognition. This structure is based on the integration of time-delay neural networks (TDNN) which have several TDNNs separated according to the duration of phonemes. As a result, the proposed structure deals with phonemes of varying duration more effectively. In the experimental evaluation of the proposed structure, 16 English vowel recognition was performed using 5268 vowel tokens picked from 480 sentences spoken by 140 speakers (98 males and 42 females) on the TIMIT (TI-MIT) database. The number of training tokens and testing tokens was 4326 from 100 speakers (69 males and 31 females) and 942 from 40 speakers (29 males and 11 females), respectively. The result was a 60.5% recognition rate (around 70% for a collapsed 13-vowel case), which was improved from 56% in the single TDNN structure, showing the effectiveness of the proposed structure's use of temporal information
Kin selection and virulence in the evolution of protocells and parasites (1994)

The evolution of parasite virulence and the origin of cooperative genomes in primitive cells are both problems that balance cooperative and competitive interactions among symbionts. I analyse the trade-off among three correlated traits: competitiveness against other genotypes for resources within hosts (protocells), damage to the host (virulence), and rate of horizontal transmission from one host to another. All three life-history components are strongly influenced by kin selection. For example, when genetic relatedness within hosts is high, each genotype is competing for resources with closely related genotypes. This competition among relatives favours increased horizontal transmission to colonize new hosts and compete against non-relatives. My analysis shows that many aspects of parasite and protocell evolution must be studied with the theoretical tools of social evolution. I discuss extensions that are required for a general theory of symbiosis.
Measurement of interstitial fluid pressure (IFP) and circulating biomarkers in soft tissue sarcoma (STS): An exploratory phase II clinical and correlative study of sorafenib (SOR) in patients with refractory STS (NCI Protocol 6948). (2010)

10091 Background: Interstitial hypertension may contribute to chemo-resistance in STS. Sorafenib is a small molecule tyrosine kinase inhibitor with potent activity against c-RAF/B-RAF, VEGFR-2, and PDGFR-β. By affecting vascular permeability, SOR may potentially reduce IFP. We assessed anti-tumor activity and measured the IFP and circulating biomarkers in patients with superficial refractory STS treated with SOR. Methods: Eligibility criteria included advanced/metastatic STS with no known curative therapy, measurable disease with at least one superficial lesion (>1cm) amenable to biopsy, age ≥18, ECOG performance status ≤2, and no prior SOR therapy. SOR was administered at 400mg BID. IFP measurements were performed intraoperatively as described (Boucher et al 1991); plasma biomarkers were collected pre- and on Day 28 post-SOR. Results: Fifteen patients (median age 59, range 30-84) were enrolled, 14 of whom had prior chemotherapy and/or radiation. Median tumor size was 6.6cm (range 1.3-10.7cm). Common sarcoma sub-types included leiomyosarcoma (27%), myxofibrosarcoma (13%) and synovial sarcoma (13%). Of these, 11 had superficial tumor amenable to biopsy. In this group, median TTP was 28 days (range 10-81). In four pts lacking palpable superficial tumor, mean TTP was 173 days (range 28-227). Best response was stable disease in 10 of 15 pts, maintained for a median 57 days (range 20-168 days). IFP measurements were obtained in 6 pts at baseline and showed a direct correlation with tumor size (Kendall's tau=0.87, p=0.017). Two pts with SD had corresponding post-SOR IFP evaluation and demonstrated a decline in IFP. SOR significantly increased plasma VEGF, PlGF and SDF-1a and decreased sVEGFR2 (p<0.05 for all). Conclusions: SOR has modest benefits in this population, most of whom had advanced refractory disease. IFP appears to decrease when response is maintained. Biomarker changes were consistent with inhibition of angiogenesis by SOR. Author Disclosure Employment or Leadership Position Consultant or Advisory Role Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Amgen, ARIAD, ArQule, AstraZeneca, Bayer, Daiichi Sankyo, Dyax, Genentech, Infinity, Johnson & Johnson, Millennium, Novartis, Pfizer, PharmaMar, Regeneron, Roche, SynDevRx, ZIOPHARM Oncology SynDevRx Novartis, Pfizer, PharmaMar Amgen, ARIAD, ArQule, Daiichi Sankyo, Genentech, Infinity, Johnson & Johnson, Novartis, Pfizer, PharmaMar, Roche, ZIOPHARM Oncology ARIAD, ArQule, Daiichi Sankyo, Infinity, Johnson & Johnson, PharmaMar
CP‐93,129, sumatriptan, dihydroergotamine block c‐fos expression within rat trigeminal nucleus caudalis caused by chemical stimulation of the meninges (1992)

1. The effects of intravenously administered 5-HT1B receptor agonists were examined on c-fos like immunoreactivity, an indicator of neuronal activation, within the brain stem. C-fos was induced by injecting an algesic, vasoconstrictor substance (0.3 ml of autologous blood) or a pro-inflammatory molecule, carrageenin (1 mg in 0.1 ml saline) into the cisterna magna of pentobarbitone-anaesthetized Sprague-Dawley rats and was visualized in serial sections (50 micrometers) by use of a polyclonal antiserum. 2. As previously reported, the injection of blood caused significant labelling within laminae I, IIo of the trigeminal nucleus caudalis, a major nociceptive brain stem nucleus, as well as within nucleus of the solitary tract and area postrema. A similar pattern of expression with fewer cells per section was detected after carrageenin instillation. The number of expressing cells was reduced by 54% in trigeminal nucleus caudalis but not within the nucleus of the solitary tract or area postrema when blood was injected in adult rats neonatal capsaicin treatment. 3. Pretreatment with 5-HT1 agonists with some selectivity for the 5-HT1B receptor, CP-93,129 (460 nmol kg-1 x 2, i.v.), sumatriptan (720 nmol kg-1 x 2, i.v.) or dihydroergotamine (86 nmol kg-1 x 2, i.v.) reduced positive cells by 39%, 31%, and 33% respectively in trigeminal nucleus caudalis but not in nucleus of the solitary tract or area postrema after blood instillation. Pretreatment with the analgesic morphine (15 mumol kg-1, s.c.) also decreased the number of positive cells by 63% in trigeminal nucleus caudalis. 4. CP-93,129 (460 nmol kg-1 x 2, i.v.) reduced the number of c-fos labelled cells by 47% within lamina I, IIo after carrageenin instillation. 5. Drug-induced blockade appeared to be tissue-dependent. Pretreatment with sumatriptan (720 nmol kg-1 x 2, i.v.) did not block c-fos expression in trigeminal nucleus caudalis following formalin application to the nasal mucosa.6. Drug-induced blockade may be mediated by an action on primary afferent (trigeminovascular) fibres in as much as CP-93,129 (460 nmol kg-' x 2, i.v.) did not reduce the number of expressing cells within the trigeminal nucleus caudalis following blood instillation in rats treated as neonates with capsaicin.7. We infer from these results that the analgesic actions of agonists at 5-HTB receptors (the receptor subtype analogous to 5-HTID in man) need not depend upon the presence of vasodilatation and, that 5-HTID receptor-mediated blockade of neurotransmission contributes significantly to the analgesic effects of these drugs in headache.8. Based on the demonstrated effects of 5-HTB/D agonists against the actions of two chemicallyunrelated meningeal stimulants, we suggest that treatment with 5-HTID agonists may be useful for the alleviation of pain in other headache conditions associated with meningeal irritation. Bacterial, viral(including AIDS meningovascular inflammation) and other forms of chemical meningitis merit further investigation.
Compressing 3D-CNNs for Hardware-Efficient Object Classification in Video Streams (2018)

This paper presents a set of methods for effective compression of 3D-CNN deep learning architectures with a particular focus on embedded platforms. Deep learning models are massive regarding the number of parameters, especially in video processing. Such memory consumption poses a challenge when it comes to efficient deployment to embedded devices. The authors applied a series of quantization and pruning techniques and showed that it is possible to significantly reduce an 80M-parameters-large deep learning model with a negligible (approx. 1 perc.) decrease in accuracy.
Microwave-Assisted Conversion of Nitriles to Thioamides in Solvent-Free Condition (2003)

Abstract Nitriles are efficiently transformed to thiomorpholides via the Willgerodt-Kindler reaction under microwave irradiation in solvent-free conditions.
Optimization of standard cell libraries for low power, high speed, or minimal area designs (2002)

A methodology for optimization of device sizes in CMOS standard cell libraries is described. The libraries are generated by compilers that allow for design rule and device size parameterization. Device sizes are optimized to achieve a low power, high speed, or minimal layout area cell library. The device sizing algorithms have been exercised on more than 80 different processes from 25 silicon foundries. This paper describes the three sizing algorithms and presents cell performance data and results from standard cell designs implemented with the three cell libraries.
Feasibility and Accuracy of Transthoracic Doppler Echocardiographic Estimation of Pulmonary Capillary Wedge Pressure Applying Different Methods (2001)

Semiquantitative prediction of elevated PWP by Doppler echocardiography is feasible as well as accurate in daily clinical practice. However, accuracy of numeric estimates is limited. Hence, invasive measurement of PWP is still necessary in certain clinical settings.
Modified Immunoradiometric Assay of Parathyroid Hormone-Related Protein: Clinical Application in the Differential Diagnosis of Hypercalcemia (1992)

We have developed a sensitive, specific solid-phase immunoradiometric assay (IRMA) of parathyroid hormone-related protein (PTH-RP) with use of affinity-purified polyclonal immunoglobulins. Antibodies recognizing PTH-RP(37-74) are immobilized to a polystyrene bead to "capture" analytes from the sample; antibodies to epitopes within the 1-36 amino acid region of PTH-RP are labeled with 125I. This IRMA recognizes PTH-RP(1-74) and PTH-RP(1-86) equivalently, but does not detect N-terminal or C-terminal fragments of PTH-RP, intact human parathyrin (PTH), or fragments of PTH. PTH-RP is not stable in plasma at 3-5 degrees C or room temperature, but a mixture of aprotinin (500 kallikrein units/L) and leupeptin (2.5 mg/L) improves PTH-RP stability in blood samples. In plasma collected in the presence of these protease inhibitors from normal volunteers and patients with various disorders of calcium metabolism, PTH-RP concentrations were above normal (greater than 1.5 pmol/L) in 91% (42 of 46) of patients with hypercalcemia associated with nonhematological malignancy. In plasma from patients with other hypercalcemic conditions (e.g., primary hyperparathyroidism, sarcoidosis, and vitamin D excess), PTH-RP was undetectable. Above-normal concentrations of PTH-RP and total calcium decreased to normal in a patient with an ovarian cyst adenocarcinoma after surgical removal of the tumor. We conclude that PTH-RP is related to and probably the causative agent of hypercalcemia in most patients with cancer, and that measurements of PTH-RP are useful in the diagnosis and management of patients with tumor-associated hypercalcemia.