gebhart/patrepeval huggingface dataset:
Plasma Anodized Aluminum Oxide Films (1964)

A low‐pressure gas plasma of oxygen ions has been used as the electrolyte for anodizing evaporated aluminum films on glass substrates. The oxide film grows at 22Aå/v at low voltages, while above 50v, the growth rate is somewhat less. Films have been anodized up to 90v. Capacitors formed of such plasma anodized aluminum films with aluminum counterelectrodes are almost entirely free of pinholes and other faults so that they exhibit very low and nearly nonpolar leakage currents. Capacitors anodized at 50v have shown excellent electrical and life performance when operated at 20v, even at temperatures of 150°C.
Purification and Partial Sequencing of High‐Affinity Progesterone‐Binding Site(s) from Porcine Liver Membranes (1996)

High-affinity progesterone-binding sites have been identified, characterized in and purified from porcine liver membranes. They were functionally solubilized by the non-denaturing zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid (Chaps, 20 mM. detergent/protein mass ratio 4:1) at a yield of 75-80%. Using [3H]progesterone as radioligand, binding studies showed high-affinity and low-affinity binding sites in microsomal preparations with an apparent Kd2 of 11 nM and an apparent Kd2 of 286 nM. In solubilized fractions the high-affinity binding sites were present at an apparent Kd2 of 69 nM. In both preparations, progesterone binding was time-dependent, saturable, reversible, and showed a similar hierachy of affinities for related steroids. A purification scheme was developed based on anion-exchanger procedures. The purified fraction as identified by maximum specific progester-one-binding activity contained two major polypeptides of apparent molecular masses (SDS/PAGE) of 28 kDa and 56 kDa, respectively. Sequencing of both polypeptides showed an identical amino terminus without significant identity in the amino acid sequence to any known protein primary structure.
Di‐(<i>trans</i>‐4‐Alkylcyclohexyl)‐α‐Diketones A New Class of Liquid Crystal Compounds (1979)

Abstract Up to the present time it was assumed that the properties of liquid crystal compounds arise not only from the presence of long chain molecules, but that these molecules must further contain at least two phenyl rings. However recent work has shown that complete hydrogenation of derivatives of alkylbenzoic acids, 2,3 as well as of alkylcyanobiphenyls, 4 leads to compounds with liquid crystal properties. Continuing our work on liquid crystals, 1 we report here on di‐( trans ‐4‐alkylcyclohexyl)‐1,2‐ethanediones 6a–c , which are the first representatives of a further class of saturated liquid crystal compounds.
Double Compounds of Urea with Magnesium Nitrate and Magnesium Sulfate (1937)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDouble Compounds of Urea with Magnesium Nitrate and Magnesium SulfateJ. Y. Yee, R. O. E. Davis, and S. B. HendricksCite this: J. Am. Chem. Soc. 1937, 59, 3, 570–571Publication Date (Print):March 1, 1937Publication History Published online1 May 2002Published inissue 1 March 1937https://pubs.acs.org/doi/10.1021/ja01282a040https://doi.org/10.1021/ja01282a040research-articleACS PublicationsRequest reuse permissionsArticle Views144Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Implementation and Experimental Results of a Quaternion-Based Kalman Filter for Human Body Motion Tracking (2006)

A human body motion tracking system based on use of the MARG (Magnetic, Angular Rate, and Gravity) sensors has been under development at the Naval Postgraduate School and Miami University. The design of a quaternion-based Kalman filter for processing the MARG sensor data was described in [1]. This paper presents the real-time implementation and testing results of the quaternion-based Kalman filter. Experimental results validate the Kalman filter design, and show the feasibility of the MARG sensors for real-time human body motion tracking.
Recombinant thyroid peroxidase-specific autoantibodies. I. How diverse is the pool of heavy and light chains in immunoglobulin gene libraries constructed from thyroid tissue-infiltrating plasma cells (1994)

Thyroid peroxidase (TPO) autoantibodies are a distinguishing feature of autoimmune thyroid disease. We have previously constructed immunoglobulin G heavy (H) and light (L) chain cDNA libraries from intrathyroidal B-cells. TPO-selected autoantibodies expressed by combined H and L chain libraries (combinatorial libraries) recognized a limited number of epitopes on TPO and used only a few of the many H and L chain variable region genes present in the genome (germline genes). One possible explanation for this restriction is a lack of diversity in the parental H and L chain gene libraries used to construct the combinatorial library. To address this issue, we determined the nucleotide sequences of randomly selected H and kappa L chain variable region genes from a pair of H and L chain libraries. The 12 H chain gene sequences analyzed were highly diverse, and none resembled the genes of TPO-selected autoantibodies. The sequences of 14 randomly selected kappa L chain genes were less diverse; 12 of 14 were closely related to the same germline gene (KL012) used by TPO-specific autoantibodies. However, we observed previously that only about 1 in 500 of the L chains in this library can pair with an H chain and bind TPO. We now find that, with 1 exception, the randomly selected KL012-like genes in the L chain library differ significantly from the antigen-specific KL012-like genes, particularly in the antigen-binding regions. In summary, the present data indicate that 1) the restricted number of H chain genes used by TPO-specific autoantibodies cannot be ascribed to limited H chain gene diversity in the parent library; and 2) L chains from combinatorial libraries (even when related to the same germline gene) cannot simply be regarded as plastic, or promiscuous, partners for high affinity antigen binding by a particular H chain.
MULTI‐STAGE SELECTION STRATEGIES: A MONTE CARLO INVESTIGATION OF EFFECTS ON PERFORMANCE AND MINORITY HIRING (1996)

This study explores alternative selection strategies available when a firm has two valid predictors that differ in the magnitude of subgroup differences. We examine 14 different selection rules (e.g., select on a composite of the two predictors versus screen on the first and then select on the second versus screen on the first and then select on a composite of the two), and document through a Monte Carlo simulation that the various selection rules can produce markedly different consequences in terms of the level of job performance achieved and the level of minority representation achieved. The selection rules examined include the use of within‐group norming, whichwas restricted by the Civil Rights Act of 1991, and the study examines how selection rules that do and do not include within‐group norming fare in terms of the tradeoffs between performance and minority representation. The study shows that the preferred selection strategy will depend on the relative value the firm places on performance and on minority representation, and that the effects of different screen‐then‐select selection strategies vary as a result of the selection ratios at the screening and selection stages, thus precluding simple conclusions about the merits of each selection strategy.
Initial Reliability and Validity of the Ohio State University TBI Identification Method (2007)

Objectives Evaluate the psychometric properties of indices of a lifetime history of traumatic brain injury (TBI). Participants Convenience samples recruited from 2 treatment programs for persons with substance use disorders: N = 119 (study 1) and N = 103 (study 2) Design Test interrater reliability (study 1) and predictive validity (Study 2). Measures Summary indices of the number, severity, timing, and effects of lifetime TBIs calculated from data elicited via a structured interview. Results Interrater reliability was high. Factor analysis showed indices could be characterized by severity weighted counts of the number of injuries, both lifetime and in childhood, number of symptoms persisting, worst injury, time since last TBI with loss of consciousness, and age at first TBI with loss of consciousness. Age at injury and symptoms persisting contributed independently to the prediction of common cognitive and behavioral consequences of TBI. Conclusion These results provide preliminary support for the reliability and validity of summary indices of lifetime history of TBI elicited via a structured interview.
Event-synchronous cancellation of the heart interference in biomedical signals (1994)

A two-pass adaptive filtering algorithm is proposed for cancellation of recurrent interferences such as the heart interference in biomedical signals. In the first pass, an average waveform in one period of the interference is estimated by event-synchronous (QRS-synchronous) averaging of the corrupted signal. In a second pass, an adaptive Schur recursive least squares (RLS) lattice filter is used to cancel the interference by using the event synchronously repeated estimated average waveform of the interference as an artificial reference signal. One key feature of this approach is that the ECG is only used for QRS synchronization and not directly as a reference signal for adaptive filtering. Thus the proposed algorithm can be applied to interference problems where ECG and true interference are almost synchronous but show considerably different waveforms. This is usually the case with the heart interference in biomedical signals. Both off-line and real-time implementations of the event synchronous interference canceller are described. The method is applied to the cancellation of the heart interference in magnetoencephalogram (MEG) signals and to the effective isolation of ventricular extrasystoles (VES) in magnetocardiogram (MCG) signals. Experimental results are shown. The new method typically attenuates the amplitudes of R-wave and T-wave interference components by an amplitude factor of 30 without influencing the MEG events of interest.
Repository evaluation of software reuse (1993)

The use and benefits of repository evaluation of software reuse are illustrated through an analysis of the evolving repositories of two large firms that recently implemented integrated CASE development tools. The analysis shows that these tools have supported high levels of software reuse, but it also suggests that there remains considerable unexploited reuse potential. The findings indicate that organizational changes will be required before the full potential of the new technology can be realized.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Bacteriophage and spliceosomal proteins function as position-dependent<i>cis/trans</i>repressors of mRNA translation<i>in vitro</i> (1992)

The translational regulation of ferritin expression currently represents the only well characterized example for eukaryotic translational control by high affinity interactions between a specific cytoplasmic protein, iron regulatory factor [IRF], and an mRNA-binding site, the iron-responsive element [IRE], located in the 5' untranslated region [UTR] of ferritin mRNAs. To elucidate whether IRE/IRF may represent the first physiological example of a more general mechanism for mRNA-specific translational control, high affinity RNA-binding sites for the bacteriophage MS2 coat protein or the spliceosomal protein U1A were introduced into the 5' UTR of capped chloramphenicol acetyltransferase [CAT] transcripts. In the absence of these RNA-binding proteins, CAT mRNA was efficiently translated. Addition of purified MS2 coat protein or U1A caused a specific, dose-dependent repression of CAT biosynthesis in rabbit reticulocyte and wheat germ in vitro translation systems. The translational blockage imposed by the RNA/protein complex was reversible and did not alter the stability of the repressed mRNAs. Translational repression caused by binding of U1A or MS2 proteins to their target mRNAs is shown to be position-dependent in vitro. Thus, mRNA/protein complexes without an a priori role in eukaryotic mRNA translation function as translational effectors with characteristics resembling those of IRE/IRF.
Reactions of N,N,N',N'-Tetramethyl-α,ι-diaminoalkanes with α,ι-Dihaloalkanes. II. x-y Reactions (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of N,N,N',N'-Tetramethyl-α,ι-diaminoalkanes with α,ι-Dihaloalkanes. II. x-y ReactionsA. Rembaum and H. NoguchiCite this: Macromolecules 1972, 5, 3, 261–269Publication Date (Print):May 1, 1972Publication History Published online1 May 2002Published inissue 1 May 1972https://pubs.acs.org/doi/10.1021/ma60027a007https://doi.org/10.1021/ma60027a007research-articleACS PublicationsRequest reuse permissionsArticle Views452Altmetric-Citations97LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of Nafion Dispersion on the Stability of Pt /  WO 3 Electrodes (1996)

Coelectrodeposited electrodes have very high activity for the oxidation of methanol and formic acid. However, has a slight solubility at 60°C in sulfuric acid media and this significantly reduces its activity and stability. By covering such an electrode with a thin layer of Nafion dispersion, the solubility of is reduced significantly, electrode performance is stable, and electrode activity is not affected.
Dielectric modelling of optical spectra of thin In<sub>2</sub>O<sub>3</sub>: Sn films (2002)

Optical transmittance spectra of In2O3 : Sn (ITO) films were simulated with a computer program based on dielectric modelling. The films were prepared by radiofrequency sputtering under various oxygen fluxes such that the carrier density varies from 3×1019 to 1.5×1021 cm-3. The dielectric function used is the sum of three types of electronic excitations: intraband transitions of free electrons (Drude model), band gap transitions, and interband transitions into the upper half of the conduction band. The parameters of these excitations are evaluated as a function of the carrier density. The damping in the Drude term was modelled frequency-dependent to account for the low extinction coefficient observed in the visible spectral range. The parameters resulting from the optical measurements were compared with those from the electrical measurements. Both the optical mobility and carrier density are found to be higher than those of the respective electric parameters. These discrepancies are attributed to a pronounced microstructure with badly conducting grain boundaries. The refractive index at 550 nm decreases linearly with increasing electron concentration. This is due both to the shift of the plasma edge and the Burstein-Moss shift of the band edge. All band gap transitions go up to the Fermi level.
An intelligent opportunistic maintenance (OM) system: A genetic algorithm approach (2009)

Complex systems like aircrafts, space shuttles, nuclear power stations, and some complicated process industries operate under high reliability and safety requirements due to the complicated technology involved and hazardous consequences to the larger community in case of failures. The maintenance regime of complex systems most often consists of a variety of maintenance strategies, like preventive maintenance, corrective maintenance, condition-based maintenance and so on. Opportunistic or opportunity-based maintenance (OM) gives the maintenance staff an opportunity to replace or repair those items, which are found to be defective or needs replacement in the immediate future, during the maintenance of a machine or component. This work presents an intelligent method of how to decide whether a particular item requires opportunistic maintenance or not, and if so how cost effective this opportunity-based maintenance will be when compared to a probable future grounding. This maintenance strategy is considered important when dealing with complex systems that contain expensive items with hard lives with condition-based maintenance (CBM) strategies. Genetic algorithms (GA) are employed to decide whether opportunistic maintenance is cost effective or not. An example of applying opportunistic maintenance strategy in process industry is used to describe the methodology for genetic algorithms.
High-power Nd-doped fiber amplifier for coherent intersatellite links (1999)

Intersatellite optical communication links require laser beams of at least 1 W of power modulated at gigahertz frequencies. They can be delivered by a master oscillator power amplifier system which consists of a stable single-frequency Nd:YAG laser, a high-speed phase modulator, and an optical amplifier. To allow coherent detection, the polarization state must be stable and controllable at the amplifier output and the phase noise must be kept low. We report here the design and the experimental results of a diode laser-pumped double clad Nd-doped fiber amplifier with polarization control, 30-dB gain, and about 1.3 W of output power.
SOMATIC EMBRYOGENESIS IN LONG‐TERM CALLUS CULTURES OF ZEA MAYS L. (GRAMINEAE) (1984)

Long‐term (1 yr), soft, embryogenic callus tissue cultures were established from excised immature embryos of a commercial cultivar of hybrid maize ( Zea mays L.). Plant regeneration occurred by the formation of somatic embryos, and the regenerated plants were morphologically normal with 2 n = 20 chromosomes. Such cultures may be useful for the isolation of mutants and the establishment of embryogenic cell suspension cultures.
Will Hemoperfusion Be Useful for Cancer Chemotherapeutic Drug Removal? (1980)

One of the major problems in clinical cancer chemotherapy is the inability to safely administer full therapeutic doses of specific drugs in the face of dysfunction of an organ system controlling that drug's metabolism and excretion. Should efficient drug removal from blood be possible following full therapeutic doses and after tumor exposure, then theoretically, even in the presence of organ dysfunction, anticancer drug toxicity may be reduced or avoided. Preliminary experiments in our laboratory have shown that adriamycin may be efficiently removed by activated charcoal from aqueous and protein solutions and blood in vivo, and that daunorubicin is removed in vitro to the same extent. However, although methotrexate is removed efficiently in vitro and extracted 50% in vivo by charcoal hemoperfusion, its overall pharmacokinetics do not appear to be altered in comparison with the alteration in pharmacokinetics of adriamycin achieved with charcoal hemoperfusion. Computer modeling has suggested that efficient adriamycin removal is achievable, and that clinical studies are warranted. For methotrexate removal, however, previous clinical studies and our own data suggest that charcoal hemoperfusion has little utility unless a highly specific sorbent for methotrexate removal can be developed.
Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor Growth <i>In Vivo</i> (2018)

<b>Purpose:</b> Survivin is an inhibitor of apoptosis protein (IAP) that is highly expressed in many cancers and represents an attractive molecule for targeted cancer therapy. Although primarily regarded as an intracellular protein with diverse actions, survivin has also been identified in association with circulating tumor exosomes.<b>Experimental Design:</b> We have reported that active, specific vaccination with a long peptide survivin immunogen leads to the development of survivin-specific CD8-mediated tumor cell lysis and prolongation of survival in tumor-bearing mice. In addition to cellular antitumor responses, circulating anti-survivin antibodies are detected in the serum of mice and human glioblastoma patients following vaccination with the survivin immunogen.<b>Results:</b> Here we demonstrate that survivin is present on the outer cell membrane of a wide variety of cancer cell types, including both murine and human glioma cells. In addition, antibodies to survivin that are derived from the immunogen display antitumor activity against murine GL261 gliomas in both flank and intracranial tumor models and against B16 melanoma as well.<b>Conclusions:</b> In addition to immunogen-induced, CD8-mediated tumor cell lysis, antibodies to the survivin immunogen have antitumor activity <i>in vivo</i> Cell-surface survivin could provide a specific target for antibody-mediated tumor immunotherapeutic approaches. <i>Clin Cancer Res; 24(11); 2642-52. ©2018 AACR</i>.
Quantum well electron transfer waveguide with high coupling efficiency to single-mode fiber (1995)

We demonstrate low fiber-waveguide coupling loss in a large optical mode barrier reservoir and quantum well electron transfer (BRAQWET) modulator. Electrooptic efficiency and propagation loss are comparable to those measured in a conventional waveguide structure with the same active material.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
One‐Pot Reaction to Synthesize Biocompatible Magnetite Nanoparticles (2005)

Biocompatible magnetite nanocrystals (see Figure) are prepared by thermal decomposition of ferric triacetylacetonate in 2-pyrrolidone in the presence of monocarboxyl-terminated poly(ethylene glycol) (MPEG-COOH). The results reveal that MPEG is covalently bound to the nanocrystal surface by COOH groups. Magnetic resonance imaging (MRI) experiments indicate that the coated nanocrystals are potential MRI contrast agents due to their excellent water solubility and biocompatibility.