gebhart/patrepeval huggingface dataset:
Improved gas chromatography packings with fluidized drying (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTImproved gas chromatography packings with fluidized dryingRichard F. Kruppa, Robert S. Henly, and D. L. SmeadCite this: Anal. Chem. 1967, 39, 7, 851–853Publication Date (Print):June 1, 1967Publication History Published online1 May 2002Published inissue 1 June 1967https://pubs.acs.org/doi/10.1021/ac60251a002https://doi.org/10.1021/ac60251a002research-articleACS PublicationsRequest reuse permissionsArticle Views14Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
GPU acceleration of cutoff pair potentials for molecular modeling applications (2008)

The advent of systems biology requires the simulation of ever-larger biomolecular systems, demanding a commensurate growth in computational power. This paper examines the use of the NVIDIA Tesla C870 graphics card programmed through the CUDA toolkit to accelerate the calculation of cutoff pair potentials, one of the most prevalent computations required by many different molecular modeling applications. We present algorithms to calculate electrostatic potential maps for cutoff pair potentials. Whereas a straightforward approach for decomposing atom data leads to low compute efficiency, a newer strategy enables fine-grained spatial decomposition of atom data that maps efficiently to the C870's memory system while increasing work-efficiency of atom data traversal by a factor of 5. The memory addressing flexibility exposed through CUDA's SPMD programming model is crucial in enabling this new strategy. An implementation of the new algorithm provides a greater than threefold performance improvement over our previously published implementation and runs 12 to 20 times faster than optimized CPU-only code. The lessons learned are generally applicable to algorithms accelerated by uniform grid spatial decomposition.
Oxidative stress status in follicular fluid and oocyte quality in women with polycystic ovary syndrome treated with inositol (2013)

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MRPrimerW: a tool for rapid design of valid high-quality primers for multiple target qPCR experiments (2016)

Design of high-quality primers for multiple target sequences is essential for qPCR experiments, but is challenging due to the need to consider both homology tests on off-target sequences and the same stringent filtering constraints on the primers. Existing web servers for primer design have major drawbacks, including requiring the use of BLAST-like tools for homology tests, lack of support for ranking of primers, TaqMan probes and simultaneous design of primers against multiple targets. Due to the large-scale computational overhead, the few web servers supporting homology tests use heuristic approaches or perform homology tests within a limited scope. Here, we describe the MRPrimerW, which performs complete homology testing, supports batch design of primers for multi-target qPCR experiments, supports design of TaqMan probes and ranks the resulting primers to return the top-1 best primers to the user. To ensure high accuracy, we adopted the core algorithm of a previously reported MapReduce-based method, MRPrimer, but completely redesigned it to allow users to receive query results quickly in a web interface, without requiring a MapReduce cluster or a long computation. MRPrimerW provides primer design services and a complete set of 341 963 135 in silico validated primers covering 99% of human and mouse genes. Free access: http://MRPrimerW.com.
Wavelet analysis of the autonomic outflowof the pupil's variation in normal subjects, given stimuli (2011)

This paper presents preliminary results of Wavelet analysis of the pupil size variation signal. A Pupillometer has been developed in order to detect the pupil's variation in time in a non-invasive way. The output signal of the equipment expresses the pupil's features variation in time (area, perimeter, vertical diameter, horizontal diameter). We know that the Autonomic Nervous System (ANS) is divided into the Sympathetic and Parasympathetic components and theoretically they are always competing with each other as a two oscillator model. The aim of this project is to identify these components and their frequency bands. With the present results we show that the signal from the pupil's variation has two major frequency bands, the first being the 0–1 Hz band (LF — Low Frequency) and the second being 1–2Hz band (HF — High Frequency). From the literature we know that the Sympathetic Nervous System (SNS) behaves in a lower frequency than the Parasympathetic (PSNS) one. This means that SNS oscillates in the LF band and PSNS oscillates in the HF band.
ChemInform Abstract: Precision Synthesis of Biodegradable Polymers (2012)

Abstract Review: 36 refs.
An innovative non-intrusive load monitoring system for commercial and industrial application (2012)

Over more than 30 years development of Non-intrusive Load Monitoring (NILM), many technologies were developed from sampling frequency 1 Hz to hundreds kHz to extract from simple information such as difference power dP, dQ; shape of transient signatures to complex information such as harmonics or electromagnetic interference (EMI). There are now many real NILM systems in residential applications but there is lack of researches to apply NILM to commercial and industrial application. This site uses so much energy in business and production so that analyzing power consumption to optimize their operation is very important to produce competitive products on the market. Unfortunately, it is very difficult to recognize commercial and industrial machine that are composed of many electric elements. This paper provides a new NILM approach to monitor commercial and industrial machines based on basic electrical appliances inside architecture of machine. All power differences dP, dQ, dS are used to analyze and classify basic electrical appliances. Adaptive filter CUSUM is used to improve removing noise in preprocessing phase of the NILM system. Finally, Field Program Gate Array (FPGA) is discussed to implement our NILM system.
Three dimensional structure prediction of SARS coronavirus S protein (2003)

Protein fold recognition method can detect similarities between protein structures in the absence of se-quence similarity.In this paper,we introduced the application of this method to predict the3D structure of n-ter-minal portion of SARS coronavirus S protein.In our model,the n-terminal portion of SARS coronavirus S protein is an all-beta protein with a single-stranded right-handed beta-helix fold.
The Dominican Sisters of the Eucharist (1945)

From its very beginning the Dominican Order has always manifested its vitality by giving effect to new ways of spiritual and apostolic life. It was not by the well-trodden path of enclosure, stability and retirement from the world that St. Dominic chose to lead his friars. His experience with the Albigensians had shown him that to meet the needs of the time other means must be found. Those means he had the vision and the courage to adopt. What struck his contemporaries about St. Thomas seems to have been his novelty, an imputation of which he might well be proud for it was his courage in bringing forth old truths in a new form that gave to the Church his synthesis of Aristotelianism and Platonism. It is not surprising, then, to learn that in the 20th century, as in the 13th, the Order of Preachers finds new ways, especially suited to the conditions of the time, of fulfilling its vocation of contemplata, aliis tradere .
Metal/semiconductive polymer Schottky device (1991)

Development of a metal/organic-semiconductor Schottky junction as an alternative to the metal/inorganic-semiconductor junction is reported. Metal/polypyrrole (PP) junctions have been prepared with electrochemically deposited doped PP films of different thickness and various metals (In, Sn, Ti, and Al) as electrodes. The electrical characteristics of the junction depend upon the work functions of PP and the metal. It has been possible to prepare Schottky barriers on the PP films with a metal electrode having a work function lower than that of the polymer. Various physical characteristics of the polymer, work function, Fermi level, and carrier concentration have been estimated.
Facilitated Phosphatidylcholine Flip-Flop Across Erythrocyte Membranes Using Low Molecular Weight Synthetic Translocases (2001)

The transmembrane distribution of phospholipids plays an important regulatory role in human erythrocytes. Membrane-bound translocase enzymes maintain an asymmetric phospholipid distribution across the membrane monolayers by promoting transmembrane diffusion or flip-flop. Mechanistic understanding of the flip-flop process is weak at the molecular level. Recently, we discovered that amide and sulfonamide derivatives of tris(aminoethyl)amine facilitate phospholipid flip-flop across vesicle membranes; that is, they act as low molecular weight, synthetic translocases. In this report, NMR evidence is provided that suggests that the synthetic translocases work by forming a hydrogen-bonded complex with the phosphocholine headgroup which decreases headgroup polarity and promotes diffusion across the lipophilic interior of the membrane. Also cell morphology and fluorescence probe methods are used to show that these synthetic translocases facilitate phosphatidylcholine flip-flop across erythrocyte membranes. Addition of a small amount of dilauroylphosphatidylcholine to erythrocytes produces echinocyte morphology which takes days to revert back to the original discocyte shape. The rate of return is significantly accelerated by the presence of the synthetic translocases. The synthetic translocases facilitate inward-translocation (flip) of the fluorescent phosphatidylcholine probe, 1-palmitoyl-2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]aminohexanoyl)-sn-glycero-3-phosphocholine (PC-NBD).
Constant Scallop-height Machining of Free-form Surfaces (1994)

A novel approach for the NC tool-path generation of free-form surfaces is presented. Traditionally, the distance between adjacent tool-paths in either the Euclidean space or in the parametric space is kept constant. Instead, in this work, the scallop-height is kept constant. This leads to a significant reduction in the size of the CL (cutter location) data accompanied by a reduction in the machining time. This work focuses on the zig-zag (meander) finishing using a ball-end milling cutter.
Quantitative measurement of ultrasound attenuation and Hepato-Renal Index in Non-Alcoholic Fatty Liver Disease (2013)

Measurements of liver tissue using HR-Indexes, ultrasound attenuation, and tissue elasticity may be useful methods to differentiate objectively between steatosis and healthy and quantify the differences.
Large‐Area All‐Textile Pressure Sensors for Monitoring Human Motion and Physiological Signals (2017)

Wearable pressure sensors, which can perceive and respond to environmental stimuli, are essential components of smart textiles. Here, large-area all-textile-based pressure-sensor arrays are successfully realized on common fabric substrates. The textile sensor unit achieves high sensitivity (14.4 kPa<sup>-1</sup> ), low detection limit (2 Pa), fast response (≈24 ms), low power consumption (<6 µW), and mechanical stability under harsh deformations. Thanks to these merits, the textile sensor is demonstrated to be able to recognize finger movement, hand gestures, acoustic vibrations, and real-time pulse wave. Furthermore, large-area sensor arrays are successfully fabricated on one textile substrate to spatially map tactile stimuli and can be directly incorporated into a fabric garment for stylish designs without sacrifice of comfort, suggesting great potential in smart textiles or wearable electronics.
CoCoA: Coordinated Cooperative Localization for Mobile Multi-Robot Ad Hoc Networks. (2007)

Mobile robot teams are particularly suited to applications where infrastructure is unavailable or damaged since they can be used to quickly form an infrastructure-less mobile ad hoc network performing tasks in a distributed manner. In such deployment scenarios, localization of individual robots is essential for enabling many applications. In this paper, we propose CoCoA, Coordinated Cooperative localization for mobile multi-robot Ad Hoc Networks, that is low-cost, quickly deployable, energy-efficient, and provides reasonable accuracy for the applications. In CoCoA, only a subset of the robots in the mobile robot team are equipped with external localization devices (e.g. GPS, laser rangers, vision sensors). Subsequently, while robots perform their tasks, they cooperate to help localize each other without requiring static landmarks to be deployed. In addition, CoCoA coordinates the localization operations of robots to reduce energy consumption. Using detailed simulations and localization models calibrated from experimental data, we find that CoCoA is effective in reducing energy consumption while providing good localization accuracy. 1.
Repeated Cocaine Modifies the Mechanism by which Amphetamine Releases Dopamine (1997)

This study determined whether daily cocaine administration initiates a calcium requirement for the increase in extracellular dopamine produced by psychostimulants. The increase in extracellular dopamine induced by perfusion of amphetamine through a microdialysis probe in the nucleus accumbens shell was enhanced in cocaine- relative to saline-pretreated rats. The augmented portion of the amphetamine-induced increase in nucleus accumbens dopamine was abolished by the coperfusion of L- or N-type calcium channel blockers. Inhibition of calcium/calmodulin-dependent protein kinase II (CaM-KII) also prevented the augmented increase in dopamine by amphetamine, whereas inhibition of vesicular exocytosis by botulinum toxin B was ineffective. When the concentration of extracellular dopamine in the nucleus accumbens was elevated by blocking the plasmallemal dopamine transporter with GBR-12909, the augmented increase in extracellular dopamine in rats sensitized to repeated cocaine was blocked by a CaM-KII inhibitor. Pretreatment with botulinum toxin B prevented the increase in extracellular dopamine by GBR-12909 in both cocaine-pretreated and control rats. Taken together, these results demonstrate that the psychostimulant-induced enhanced increase in extracellular dopamine in the nucleus accumbens shell of cocaine-pretreated rats arises from the induction of calcium- and CaM-KII-dependent mechanisms.
Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation (1998)

PMN are an important source of pro-inflammatory cytokines in patients with intestinal inflammation and can be downregulated by IL-10.
Gab-Family Adapter Proteins Act Downstream of Cytokine and Growth Factor Receptors and T- and B-Cell Antigen Receptors (1999)

We previously found that the adapter protein Gab1 (110 kD) is tyrosine-phosphorylated and forms a complex with SHP-2 and PI-3 kinase upon stimulation through either the interleukin-3 receptor (IL-3R) or gp130, the common receptor subunit of IL-6-family cytokines. In this report, we identified another adapter molecule (100 kD) interacting with SHP-2 and PI-3 kinase in response to various stimuli. The molecule displays striking homology to Gab1 at the amino acid level; thus, we named it Gab2. It contains a PH domain, proline-rich sequences, and tyrosine residues that bind to SH2 domains when they are phosphorylated. Gab1 is phosphorylated on tyrosine upon stimulation through the thrombopoietin receptor (TPOR), stem cell factor receptor (SCFR), and T-cell and B-cell antigen receptors (TCR and BCR, respectively), in addition to IL-3R and gp130. Tyrosine phosphorylation of Gab2 was induced by stimulation through gp130, IL-2R, IL-3R, TPOR, SCFR, and TCR. Gab1 and Gab2 were shown to be substrates for SHP-2 in vitro. Overexpression of Gab2 enhanced the gp130 or Src-related kinases-mediated ERK2 activation as that of Gab1 did. These data indicate that Gab-family molecules act as adapters for transmitting various signals.
Message routing algorithms for static task scheduling (2002)

Two heuristic-based routing algorithms are presented. They take into account the need for precise information about intertask data communication which in aa message-passing, single-stage, n-dimensional network environment includes the communication delay for sending certain amounts of data at a certain moment through certain links. They also attempt to provide the best routes for communication, as well as the communication delay information on the routes. The difficulty is that for a given set of links, the communication delay can be different if the message is sent through at a different moment. The communication delay is influenced by current traffic on the links. The algorithms not only accurately compute the times that are needed to send messages from multiple-source processing elements (PEs) to a destination PE, but also indicate the paths that are used to transfer the messages. Each of the algorithms can be used in the static scheduling algorithms to computer the time needed to transfer messages in a multiprocessor system. The author also indicates that the optimal routing problem is NP-complete.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Drug Loaded Erythrocytes: As Novel Drug Delivery System (2008)

Novel drug delivery systems are one of the widely used delivery systems. In the present scenario, amongst them, "Drug Loaded Erythrocytes" is one of the growing and potential systems for delivery of drugs and enzymes. Erythrocytes are biocompatible, biodegradable, possess long circulation half-life and can be loaded with variety of biologically active substances. Carrier erythrocytes are prepared by collecting blood sample from the organism of interest and separating erythrocytes from plasma. By using various physical and chemical methods the cells are broken and the drug is entrapped into the erythrocytes, finally they are resealed and the resultant carriers are then called "resealed erythrocytes". Surface modification with glutaraldehyde, antibodies, carbohydrates like sialic acid and biotinylation of loaded erythrocytes (biotinylated erythrocytes) is possible to improve their target specificity and to increase their circulation half-life. Upon reinjection the drug loaded erythrocytes serve as slow circulation depots, targets the drug to the reticuloendothelial system (RES), prevents degradation of loaded drug from inactivation by endogenous chemicals, attain steady state concentration of drug and decrease the side-effects of loaded drug. Nowadays, Nanoerythrosomes based drug delivery systems have excellent potential for clinical application.
Biosynthesis of Branched-Chain Amino Acids in Yeast: Correlation of Biochemical Blocks and Genetic Lesions in Leucine Auxotrophs (1968)

The three enzymatic steps in the conversion of alpha-ketoisovalerate to alpha-ketoisocaproate were examined in wild-type and in leucine auxotrophic stocks of yeast. Procedures for the reliable assay of each of the enzymatic steps in crude extracts were devised. Crude extracts of the prototrophic haploid stock catalyzed all three enzymatic steps. Examination of a series of leucine auxotrophs permitted a correlation between the three enzymatic steps and the genetic lesions affecting 10 different loci. This examination revealed that a single locus (le-6) affected primarily alpha-isopropylmalate synthetase, the first step in the pathway. Lesions in six loci (le-1, le-4, le-5, le-7, le-8, and le-10) lead primarily to a deficiency in the activity of the second enzyme in the pathway, alpha-isopropylmalate isomerase. Stocks with lesions in three loci (le-2, le-3, and le-9) were primarily blocked in the third step of the pathway, catalyzed by beta-isopropylmalate dehydrogenase. The results with the mutants provide strong evidence that the pathway for leucine biosynthesis proposed by Strassman and his colleagues is the sole significant pathway in yeast.
DUAL-MICROPHONE ROBUST FRONT-END FOR ARM'S-LENGTH SPEECH RECOGNITION (2006)

This paper describes a novel method of improving the performance of a speech recognition front-end in non-stationary background noise. A two-microphone array has been designed that both enhances the speech and provides a continuous estimate of the background noise. This processing has been integrated with the standard ETSI DSR Advanced Front End so that the continuous noise estimate is an input to the first stage of Wiener filtering, increasing the noise suppression and hence the recognition performance. Tests with real-world noise have shown the recognition error rate is reduced by up to 50% when compared with single-microphone input to the same Advanced Front End.
Which Spatial Partition Trees are Adaptive to Intrinsic Dimension? (2012)

Recent theory work has found that a special type of spatial partition tree - called a random projection tree - is adaptive to the intrinsic dimension of the data from which it is built. Here we examine this same question, with a combination of theory and experiments, for a broader class of trees that includes k-d trees, dyadic trees, and PCA trees. Our motivation is to get a feel for (i) the kind of intrinsic low dimensional structure that can be empirically verified, (ii) the extent to which a spatial partition can exploit such structure, and (iii) the implications for standard statistical tasks such as regression, vector quantization, and nearest neighbor search.
A 1" format 1.5 M pixel IT-CCD image sensor for an HDTV camera system (1991)

A 1-in. format 1.5-million pixel IT (interline transfer) CCD (charge coupled device) image sensor has been developed for an HDTV (high-definition television) camera system. To achieve a low smear ratio while maintaining a high level of sensitivity, the authors have developed a new impurity profile of a buried P/sup +/-layer and an on chip microlens array whose material is a deep-UV resist. Using this sensor, a high-fidelity picture with a horizontal resolution of 820 TV lines has been obtained. The IT-CCD sensor has achieved a smear ratio of less than -90 dB, a sensitivity level of 80 nA/Lx, and a maximum charge handling capacity of 1.2*10/sup 5/ electrons.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>