gebhart/patrepeval huggingface dataset:
The effect of supplementing a symbiotic, organicacids, or β-glucanase to barley-based diets on theperformance of broiler chickens (2005)

A total of 384 male broiler chickens were divided into four groups, 12 replicates each with 8 birds per replicate. Four barley-based diets were prepared. The control diet (C) was unsupplemented, diet A was supplemented with flavomycin (10 mg/kg), diet OS was supplemented with organic acids (3 g/kg) and a symbiotic composed of a probiotic and lactose (1:2, w/w), diet E was supplemented with -glucanase (1 g/kg). Diets were fed from 1 to 35 days of age. In the OS group the body weight gain (BWG) was highest (P<0.05), while feed conversion ratio (FCR) was similar as in group E, but better (P<0.05) than in groups A and C. The viscosity of ileal digesta was 1.55 in group E, while in the remaining groups it averaged 2.37 mPas . s (P<0.05). The pH of caecal digesta was lowest in group OS (5.88), followed by E (6.06), while in groups A and C groups it averaged 6.33 (P<0.05), which points to increased production of short-chain fatty acids. It seems that a combination of organic acids and a symbiotic can replace antibiotic growth promoters in broiler diets.
Topic Detection from Blog Documents Using Users&amp;#146; Interests (2006)

In this paper, we describe a method to detect topic words from blog documents. We define "topic words" as words frequently used by people who share the same interests. In this method, each blogger’s interests are extracted from each blog site, and interest similarities between bloggers are calculated. Unusual words that are used by bloggers who have a high level of similarity are then extracted as topic words. We evaluated the precision of this method using blog documents, and the results show that the proposed method is superior (by 4.4 %) to the traditional TF-IDF method in terms of precision.
Epidemiology and burden of osteoarthritis (2013)

Further research is required to fully understand how OA affects an individual physically and psychologically, and to determine their healthcare need.
Identification and characterization of ‐3c–g acceptor splice site mutation in human α‐ <scp>l</scp>‐iduronidase associated with mucopolysaccharidosis type IH/S (2000)

DNA screening for mutations in the alpha-L-iduronidase (IDUA) gene was performed in a Chinese mucopolysaccharidosis type IH/S patient. The patient had two different mutations: the maternal allele has L346R (t-g transversion in codon 346) and the paternal allele has 388-3c-g (c-g transversion at position -3 of the 3' splice site of intron 2). In transfected COS-7 cells, L346R showed no appreciable IDUA activity (0.4% of normal activity), although it did not cause an apparent reduction in IDUA mRNA or protein level. The 388-3c-g mutation profoundly affects normal splicing leading to a very unstable mRNA. Expression of the IDUA cDNA containing the mutated acceptor splice site showed trace amounts of enzyme activity (1.6% of normal activity). The results provide further support for the importance of cytosine at the -3 position in RNA processing.
Developmental Changes in the Intracellular Ca 2+ Release Mechanisms in Porcine Oocytes1 (1997)

The presence of different intracellular Ca2+ release mechanisms in porcine oocytes and their involvement in mediating Ca2+ transients in different developmental stages were investigated. Metaphase II arrested oocytes showed an increase in intracellular Ca2+ concentration after injection of inositol 1,4,5-trisphosphate (InsP3), the InsP3 receptor agonist. Similar Ca2+ spikes could be detected after injection of ryanodine and cyclic ADP ribose, the ryanodine receptor agonists. The InsP3-induced Ca2+ release was inhibited by heparin, the InsP3 receptor antagonist, whereas procaine, the ryanodine receptor antagonist, blocked the Ca2+ transients generated by ryanodine and cyclic ADP ribose. In germinal vesicle-stage oocytes, intracellularly stored Ca2+ could also be mobilized by agonist treatment, though the effective concentration to generate the Ca2+ spikes was higher. After in vitro fertilization, repetitive Ca2+ transients were generated in oocytes starting 2.5-3 h after insemination. They ceased around the time of pronuclear formation when the oocytes entered first interphase. At this stage, the receptors were still capable of mediating Ca2+ release upon agonist treatment; in many cases these spikes were of longer duration, suggesting that in interphase it takes a longer time for the Ca2+ stores to resequester the mobilized Ca2+ from the cytosol. These results suggest that porcine oocytes possess both InsP3 and ryanodine Ca2+ channel receptors and that the properties of the Ca2+ release mechanisms change during oocyte development.
Future directions in the therapy for large bowel cancer. (1982)

The essence of clinical research success is a blending of modality-oriented development and disease oriented strategy. Development therapeutics begins with single institution pilot, or exploratory, studies in which the treatment itself is more important than the strategic approach to the disease(s) being treated. Ultimately, if the exploratory studies are encouraging, the confirmatory and explanatory studies (Phase II--III) which follow will be disease oriented. Advances in the treatment of colorectal cancer will, it is hoped, come from new developmental therapeutics in chemotherapy, radiation therapy and biologic response modifier therapy. Developments in chemotherapy involve a steady stream of new drugs which are entering clinical trial from the drug development program of the NCI as well as from the pharmaceutical industry. These drugs include new structures and analogues of structures known to be active in some tumor types. In the latter category particular emphasis is being placed on new anthracycline analogues of doxorubicin and analogues of cisplatinum diammine dichloride. Recognizing the importance of colorectal cancer experimental models for this tumor are being given prominence in the prediction for now active drugs. These include transpantable rodent colon tumors and human colon tumors grown in nude mice or in a subrenal capsule system. In addition, the clonogenic assay of human tumor stem cells is under active investigation. It is hoped that this assay will be able to help predict which patients with colorectal tumors will respond to the given available drugs, and help predict the selection of new active drugs for colorectal cancer. Examples of new developments in radiation oncology which may have eventual impact on large bowel cancer include: (1) high linear energy transfer deliverence techniques such as neutrons, heavy ions and pi-mesons; (2) radiation sensitizers such as misonidazole, desmethylmisonidazole and newer electronic affinic compounds; (3) radiation protectors such as WR-2727; and (4) new fractionation schedules. In addition hyperthermia is evolving as a viable approach to killing neoplastic cells both alone and in conjunction with x-ray therapy. The biologic response modifiers (BRM) are a new and exciting development in cancer treatment. These are materials which hopefully will modify the hosts ability to react to neoplastic cells in a way which will be of therapeutic benefit either by itself or in conjunction with other therapies. Among BRMs of current interest are the interferons and thymic hormones. The interferons have demonstrated some ability to shrink clinically evident breast cancers and lymphomas and when supplies permit studies in bowel cancer will be great interest.
cis-cis-Muconate, the product inducer of catechol 1,2-oxygenase in Pseudomonas aeruginosa (1968)

Research Article| September 01 1968 cis-cis-Muconate, the product inducer of catechol 1,2-oxygenase in Pseudomonas aeruginosa J A Bird; J A Bird 1Department of Botany (Microbiology Group), University of Newcastle upon Tyne, NE1 7RU Search for other works by this author on: This Site PubMed Google Scholar R B Cain R B Cain 1Department of Botany (Microbiology Group), University of Newcastle upon Tyne, NE1 7RU Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd © 1968 The Biochemical Journal1968 Biochem J (1968) 109 (3): 479–481. https://doi.org/10.1042/bj1090479 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation J A Bird, R B Cain; cis-cis-Muconate, the product inducer of catechol 1,2-oxygenase in Pseudomonas aeruginosa. Biochem J 1 September 1968; 109 (3): 479–481. doi: https://doi.org/10.1042/bj1090479 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1968 The Biochemical Journal1968 Article PDF first page preview Close Modal You do not currently have access to this content.
Lower Incidence of Tardive Dyskinesia with Risperidone Compared with Haloperidol in Older Patients (1999)

The atypical antipsychotic risperidone is significantly less likely to result in TD than the conventional neuroleptic haloperidol in a high-risk group of older patients, at least over a 9-month period.
Whispering gallery modes in prolate fibre microcavities (2000)

Summary form only given. Whispering gallery modes (WGMs) are resonances of circular dielectric cavities such as spheres, discs and cylinders. They can be efficiently excited by evanescent coupling from narrow tapered fibres, and their spectral properties in silica microspheres have been exploited to give add-drop filters and microlasers. We have also shown how they can be similarly excited in cylindrical fibres and used to measure diameter uniformity. We demonstrate a new type of silica microcavity with a prolate shape formed in an optical fibre using a carbon dioxide laser. Although relatively long they can be very narrow and have interesting WGM spectra. They could form the basis of new add-drop filters and microlasers that are easier to manipulate than microspheres.
Polyphenols of <i>Melaleuca quinquenervia</i> leaves – pharmacological studies of grandinin (2003)

Four polyphenolic acid derivatives and three ellagitannins were isolated from the leaves of Melaleuca quinquenervia (Clav.) S. T. Blake for the first time. Their structures were elucidated as gallic acid (1), ellagic acid (2), 3-O-methylellagic acid (3), 3,4,3'-tri-O-methylellagic acid (4), 2,3-O-hexahydroxydiphenoyl-(alpha/beta)-D-(4)C(1)-glucopyranose (5), castalin (6) and grandinin (7) on the basis of chemical, mass spectrometric (-ve ESI-MS) and spectroscopic (UV, (1)H-, (13)C NMR, (1)H,(1)H-, (1)H,(13)C-COSY, (1)H,(1)H-TOCSY and HMBC) analyses. Grandinin (the major compound) showed radical scavenging properties by its reaction with 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical [EC(50) = 4.3 +/- 0.3 micro g mL(-1)]. It was found to be relatively nontoxic in mice [LD(50) = 316 mg Kg(-1) b.wt.]. It exhibited a significant dose-dependent (35-70 mg Kg(-1)) hypoglycemic effect by significantly reducing blood glucose level in basal condition and after heavy glucose load in normal mice. Moreover, it reduced the elevated blood glucose level in STZ-induced diabetic mice. In addition, grandinin reduced the elevated blood urea nitrogen and serum lipid peroxides in STZ-induced diabetic mice.
Effects of Dietary Sodium Chloride on Red Drum Juveniles in Waters of Various Salinities (1992)

Abstract Three 8-week feeding trials were conducted to determine the effects of supplemental dietary salts on growth and osmoregulation of juvenile red drums (Sciaenops ocellatus) at various water salinities. In each experiment, sodium chloride was added to a basal diet composed of semipurified and practical ingredients; the basal diet provided intrinsic levels of 0.80% Cl, 0.84% K, and 0.92% Na on a dry-matter basis. In fresh water, red drums fed the basal diet supplemented with NaCI at 2% had significantly (P < 0.05) greater weight gain and feed efficiency than fish given the basal diet alone. In brackish water (6‰ salinity), fish given the diet supplemented with NaCI at 2% had weight gains that were numerically but not significantly (P = 0.076) greater than gains offish fed the basal diet. In full-strength artificial seawater (35‰), fish fed diets supplemented with NaCI at 2 and 10% had weight gains not significantly (P = 0.23) different from those of fish fed the basal diet, and those fed the diet supplemented with NaCl at 10% had significantly reduced feed efficiency. None of the salt supplementations significantly affected blood osmolality or total thyroid hormone levels at 4 weeks or the ability of fish maintained in brackish or fresh water to survive transfer to full-strength seawater at 8 weeks. Results from these experiments indicate that dietary supplementation with NaCI improved the growth of red drums in dilute (fresh and brackish) waters, but not in full-strength seawater. Dietary salts for red drums in dilute waters may provide ions that the fish cannot sufficiently extract from hypotonic environments.
An Advanced SOM Algorithm Applied to Handover Management Within LTE (2013)

A novel approach to handover management for Long-Term Evolution (LTE) femtocells is presented. Within LTE, the use of self-organizing networks (SONs) is included as standard, and handover management is one of its use cases. Base stations can autonomously decide whether handover should take place and assign the values of relevant parameters. Due to the limited range of femtocells, handover requires more delicate attention in an indoor scenario to allow for efficient and seamless handover from indoor femtocells to outdoor macrocells. As a result of the complexity of the indoor radio environment, frequent ping-pong handovers between the femtocell and macrocell layers can occur. A novel approach requiring a small amount of additional processing using neural networks is presented. A modified self-organizing map (SOM) is used to allow a femtocell to learn the locations of the indoor environment from where handover requests have occurred and, based on previous experience, decide whether to permit or prohibit these handovers. Once the regions that coincide with unnecessary handovers have been detected, the algorithm can reduce the total number of handovers that occur by up to 70% while still permitting any necessary handover requests to proceed. By reducing the number of handovers, the overall efficiency of the system will improve as the consequence of a reduction in associated but unnecessary signaling. Using machine learning for this task complies with the plug-and-play functionality required from SONs in LTE systems.
Xyloglucan and rβ-D-Glucan in Cell Walls of Rice Seedlings (1982)

Journal Article Xyloglucan and rβ-D-Glucan in Cell Walls of Rice Seedlings Get access Yoji Kato, Yoji Kato Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku UniversityTsutsumidori, Sendai 980, Japan Search for other works by this author on: Oxford Academic Google Scholar Shuzo Ito, Shuzo Ito Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku UniversityTsutsumidori, Sendai 980, Japan Search for other works by this author on: Oxford Academic Google Scholar Katsuhiro Iki, Katsuhiro Iki Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku UniversityTsutsumidori, Sendai 980, Japan Search for other works by this author on: Oxford Academic Google Scholar Kazuo Matsuda Kazuo Matsuda Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku UniversityTsutsumidori, Sendai 980, Japan Search for other works by this author on: Oxford Academic Google Scholar Plant and Cell Physiology, Volume 23, Issue 3, April 1982, Pages 351–364, https://doi.org/10.1093/oxfordjournals.pcp.a076357 Published: 01 April 1982 Article history Received: 29 August 1981 Accepted: 12 January 1982 Published: 01 April 1982
The concurrency control and recovery problem for multilevel update transactions in MLS systems (2002)

The problem is addressed of a transaction reading and writing data at multiple classification levels in a multilevel secure (MLS) database. The authors refer to such transactions as multilevel update transactions. They show that no scheduler can ensure atomicity of multilevel update transactions in the presence of transaction aborts and at the same time be secure. There are essentially two ways of scheduling multilevel update transactions. The first method, which ensures strong atomicity, involves delaying low-level subtransactions until the fats of the sibling high-level subtransactions are known. The second scheme, which ensures only semantic atomicity, involves compensating the effects of any committed subtransactions. Analysis of these schemes indicates that the compensation approach leads to lower covert channel bandwidths. A concurrency control and recovery protocol based on compensation is proposed for multilevel update transactions. The security and correctness of the protocol is considered.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Mutations Affecting Symmetrical Migration of Distal Tip Cells in Caenorhabditis elegans (1999)

The rotational symmetry of the Caenorhabditis elegans gonad arms is generated by the symmetrical migration of two distal tip cells (DTCs), located on the anterior and posterior ends of the gonad primordium. Mutations that cause asymmetrical migration of the two DTCs were isolated. All seven mutations were recessive and assigned to six different complementation groups. vab-3(k121) and vab-3(k143) affected anterior DTC migration more frequently than posterior, although null mutants showed no bias. The other five mutations, mig-14(k124), mig-17(k113), mig-18(k140), mig-19(k142), and mig-20(k148), affected posterior DTC migration more frequently than anterior. These observations imply that the migration of each DTC is regulated differently. mig-14 and mig-19 also affected the migration of other cells in the posterior body region. Four distinct types of DTC migration abnormalities were defined on the basis of the mutant phenotypes. vab-3; mig-14 double mutants exhibited the types of DTC migration defects seen for vab-3 single mutants. Combination of mig-17 and mig-18 or mig-19, which are characterized by the same types of posterior DTC migration defects, exhibited strong enhancement of anterior DTC migration defects, suggesting that they affect the same or parallel pathways regulating anterior DTC migration.
Lentivirally generated eGFP‐transgenic rats allow efficient cell tracking in vivo (2004)

Here we describe the efficient generation of eGFP-transgenic rats using a lentiviral approach. Analysis of the founder generation demonstrated that 46% of the offspring had stably integrated the provirus into the genome and of those 92% expressed eGFP in all blood-derived leukocytes. In contrast to their offspring, all founder rats were mosaic with regard to eGFP-expression, suggesting delayed viral transduction after injection. The expression level of eGFP in the F1 generation is influenced by and segregates with the site of proviral integration. Interestingly, a single copy of the transgene is sufficient for reliable detection by flow cytometry, irrespective of the leukocyte subtype analyzed. Adoptive transfer of purified CD4(+) T-lymphocytes from transgenic rats and subsequent reisolation from various organs further demonstrated that expression of the lentiviral transgene is maintained in a foreign host and therefore allows for efficient tracking of transferred cells. Taken together, lentivirally generated eGFP-transgenic rats are a powerful tool for various applications in immunology and presumably also many other fields.
MICROSTRUCTURE AND MECHANICAL PROPERTIES OF 8090 Al-Li ALLOY (1992)

The change of mechanical properties of the 8090 Al-Li alloy influenced by aging is attributed to the change of δ′-phase particle size and the precipitation of S′-phase.The δ′-phase may easily precipitate and rapidly grow,but the S′-phase can only precipitate with a longer stage of incubation.The precipitation of S′-phase would be promoted by cold working prior to ag- ing.The co-precipitation of δ′- and S′-phase could improve the strength and plastieity of the alloy,for which aging at 190℃.for 20—30 h seems to be optimal.In addition,the precipitate free zone( PFZ)can form at high angle grain boundary and its width is over 200 nm in peak aging condition.But at sub-grain boundary,the formation of PFZ is difficult.
Nonlinear dynamics of a noncontacting atomic force microscope cantilever actuated by a piezoelectric layer (2002)

The nonlinear equations of motion for a silicon cantilever beam, covered by a piezoelectric lead–zirconate–titanate layer, subjected to a Lennard-Jones type boundary condition, are derived for voltage excitation. The Lagrangian of the system is obtained from the electric enthalpy density, including the virtual work of the Lennard-Jones potential, assuming the beam undergoes only small displacements. By application of Hamilton’s principle, the nonlinear equations of motion are consistently derived and truncated to third order for perturbation analysis. The evolution equations are obtained by the multiple scales method and periodic solutions to the equations of motion are determined and discussed with respect to different tip to sample distances. An analytically obtained frequency response function enables determination of the frequency shift of individually piezoactuated microbeams, which are proposed as fundamental elements of parallel atomic force microscopy, undergoing forced vibration in a dissipative environment.
Dynamic load balancing in multicomputer database systems using partition tuning (1995)

Shared nothing multiprocessor architecture is known to be more scalable to support very large databases. Compared to other join strategies, a hash-based join algorithm is particularly efficient and easily parallelized for this computation model. However, this hardware structure is very sensitive to the skew in tuple distribution. Unless the parallel hash join algorithm includes some dynamic load balancing mechanism, the skew effect can severely deteriorate the system performance. In this paper, we investigate this issue. In particular, three parallel hash join algorithms are presented. We implement a simulator to study the effectiveness of these schemes. The simulation model is validated by comparing the simulation results to those produced by the actual implementation of the algorithms running on a multiprocessor system. Our performance study indicates that a naive approach is not able to provide tangible savings. However, the carefully designed strategies can offer substantial improvement over conventional techniques for a wide range of skew conditions.
Preliminary results of the mission profile life test of a 30 cm Hg bombardment thruster (1979)

The paper deals with some preliminary results of the Mission Profile Life Test planned to conduct a program of long-term test segments of 30-cm diameter thrusters and power processing units under computer control. Thruster performance data and other operational characteristics taken at various times during a test segment are compared and the results are evaluated in light of the life-timing mechanisms. Thruster control algorithms are also presented. The first test segment completed 2700 hr of a planned 4000 hr test with a J-series 30-cm thruster. The last 1600 hr used a functional model power processing unit (PPU) operated in vacuum. The thruster-PPU was controlled by a computer with software developed to control start-ups, throttling, and variety of off-normal conditions.
Sudangrass poisoning: Of livestock minimized by good management practices (1948)

Only three alleged cases of prussic acid poisoning from sudangrass were reported in California during the first nine months of 1948.