gebhart/patrepeval huggingface dataset:
Senseseer mobile-cloud-based Lifelogging framework (2013)

Smart-phones are becoming our constant companions, they are with us all of the time, being used for calling, web surfing, apps, music listening, TV viewing, social networking, buying, gaming, and a myriad of other uses. Smart-phones are a technology that knows us much better than most of us could imagine. Based on our usage and the fact that we are never far away from our smart phones, they know where we go, who we interact with, what information we consume, and with a little clever software, they can know what we are doing and even why we are doing it. They are beginning to know us better than we know ourselves. In this work we present SenseSeer a generic mobile-cloud-based mobile Lifelogging framework. This framework supports customisable analytic services for sensing the person, understanding the semantics of life activities and the easy deployment of analytic tools and novel interfaces. At present, SenseSeer supports services in many domains, such as personal health monitoring, location tracking, lifestyle analysis and tourism focused applications. This work demonstrate the design principles of SenseSeer and three of its services: My Health, My Location and My Social Activity.
Scheduling of multicast traffic in high-capacity packet switches (2002)

Switches with input buffers are scalable due to their simplicity. In these switches, the port that sources a multicast session might easily get congested as it becomes more popular. We propose that destination ports should forward copies of multicast packets to other destination ports in a specified order. In this way, the multicast traffic load is evenly distributed over the switch ports. Packets are scheduled according to the weighted sequential greedy algorithm.
Enhancement of tumor radioresponse of a murine mammary carcinoma by paclitaxel. (1994)

Paclitaxel is a chemotherapeutic agent with potent microtubule stabilizing activity that arrests cells in G2-M. Because G2 and M are the most radiosensitive phases of the cell cycle, paclitaxel has potential as a cell cycle-specific radiosensitizer. In this study, we investigated the ability of paclitaxel to increase tumor radioresponse in vivo using a murine mammary carcinoma and the dependency of this response on accumulation of tumor cells in mitosis. Mice bearing 8-mm tumors were treated with paclitaxel (60 mg/kg i.v.), 9, 15, or 21 Gy of single-dose radiation, or with a regimen of both agents in which radiation was given 1, 9, or 24 h after paclitaxel. The effect of the treatments was determined by tumor growth delay. Microscopically, the percentage of mitotically arrested cells was only 4% 1 h after treatment with paclitaxel, increased to a maximum value of 30% at 9 h, and decreased to 12% 24 h after paclitaxel. Paclitaxel enhanced tumor radioresponse by factors of 1.21 to 2.49. The degree of enhancement increased with increases in both the dose of radiation and the time between paclitaxel administration and radiation delivery. Radiation efficiently destroyed mitotically arrested cells by apoptosis. The greatest enhancement of radiation response was not at the time of the highest mitotic arrest but at 1 day after paclitaxel treatment, showing that paclitaxel potentiates tumor radioresponse by mechanisms in addition to blocking the cell cycle in mitosis, possibly by tumor reoxygenation. Thus, these results show that paclitaxel is a potent in vivo radiopotentiating agent and has the potential to be usefully combined with radiotherapy.
The infrared flux method for determining stellar angular diameters and effective temperatures (1979)

The infrared flux method for deriving stellar angular diameters and effective temperatures (Blackwell & Shallis) is elaborated and assessed in relation to the use of the intensity interferometer. Infrared magnitudes of 17 stars obtained using the Tenerife flux collector are presented and angular diameters and effective temperatures for 13 of these stars are derived using the method. A discrepancy exists between infrared photometry and the predictions of model atmosphere theory, which is probably the result of flux calibration errors. It is suggested that given a good flux calibration, the infrared flux method is capable of greater accuracy than the intensity interferometer, besides being more versatile.
Proline-rich Sequence Recognition (2009)

The tumor maintenance protein Tsg101 has recently gained much attention because of its involvement in endosomal sorting, virus release, cytokinesis, and cancerogenesis. The ubiquitin-E2-like variant (UEV) domain of the protein interacts with proline-rich sequences of target proteins that contain P(S/T)AP amino acid motifs and weakly binds to the ubiquitin moiety of proteins committed to sorting or degradation. Here we performed peptide spot analysis and phage display to refine the peptide binding specificity of the Tsg101 UEV domain. A mass spectrometric proteomics approach that combines domain-based pulldown experiments, binding site inactivation, and stable isotope labeling by amino acids in cell culture (SILAC) was then used to delineate the relative importance of the peptide and ubiquitin binding sites. Clearly "PTAP" interactions dominate target recognition, and we identified several novel binders as for example the poly(A)-binding protein 1 (PABP1), Sec24b, NFkappaB2, and eIF4b. For PABP1 and eIF4b the interactions were confirmed in the context of the corresponding full-length proteins in cellular lysates. Therefore, our results strongly suggest additional roles of Tsg101 in cellular regulation of mRNA translation. Regulation of Tsg101 itself by the ubiquitin ligase TAL (Tsg101-associated ligase) is most likely conferred by a single PSAP binding motif that enables the interaction with Tsg101 UEV. Together with the results from the accompanying article (Kofler, M., Schuemann, M., Merz, C., Kosslick, D., Schlundt, A., Tannert, A., Schaefer, M., Lührmann, R., Krause, E., and Freund, C. (2009) Proline-rich sequence recognition: I. Marking GYF and WW domain assembly sites in early spliceosomal complexes. Mol. Cell. Proteomics 8, 2461-2473) on GYF and WW domain pathways our work defines major proline-rich sequence-mediated interaction networks that contribute to the modular assembly of physiologically relevant protein complexes.
Amorphous Water-Ice Relaxations Measured with Soft-Landed Ions (1998)

${\mathrm{D}}_{3}{\mathrm{O}}^{+}$ and ${\mathrm{Cs}}^{+}$ ions $(\ensuremath{\le}1\mathrm{eV})$ were soft landed on vacuum-deposited amorphous water ice at 30 K. The samples charged capacitively with an initial dielectric constant of 2. Then the voltage was measured via a Kelvin probe while the sample temperature was ramped. A sharp drop in voltage occurred near 50 K, due to dielectric responses occurring at much less than the expected 135 K. This was due to relaxations of the highly strained amorphous ice. Preannealing the ice could move the electrical relaxation up to as high as 120 K. Ion migration through the ice was not observed below 190 K.
V-PROLI/NO, a Prodrug of the Nitric Oxide Donor, PROLI/NO (2007)

The sensitivity to decomposition of the nitric oxide (NO) donor ion, 1-[2-(carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate (PROLI/NO), complicates direct electrophilic substitution to form useful prodrug derivatives. A modified general synthetic approach involving 1-[2-(hydroxymethyl)pyrrolidin-1-yl]diazen-1-ium-1,2-diolate ion (structure A, above) was used to prepare several PROLI/NO prodrugs including the previously inaccessible O2-vinyl derivative, V-PROLI/NO. Metabolism of V-PROLI/NO by liver microsomes enriched in human cytochrome P450 isoforms was demonstrated.
Immunoglobulin E and Eosinophil-Dependent Protective Immunity to Larval<i>Onchocerca volvulus</i>in Mice Immunized with Irradiated Larvae (2004)

Mice immunized with irradiated Onchocerca volvulus third-stage larvae developed protective immunity. Eosinophil levels were elevated in the parasite microenvironment at the time of larval killing, and measurements of total serum antibody levels revealed an increase in the immunoglobulin E (IgE) level in immunized mice. The goal of the present study was to identify the role of granulocytes and antibodies in the protective immune response to the larval stages of O. volvulus in mice immunized with irradiated larvae. Immunity did not develop in mice if granulocytes, including both neutrophils and eosinophils, were eliminated, nor did it develop if only eosinophils were eliminated. Moreover, larvae were killed in naïve interleukin-5 transgenic mice, and the killing coincided with an increase in the number of eosinophils and the eosinophil peroxidase (EPO) level in the animals. To determine if EPO was required for protective immunity, mice that were genetically deficient in EPO were immunized, and there were no differences in the rates of parasite recovery in EPO-deficient mice and wild-type mice. Two mouse strains were used to study B-cell function; micro MT mice lacked all mature B cells, and Xid mice had deficiencies in the B-1 cell population. Immunity did not develop in the micro MT mice but did develop in the Xid mice. Finally, protective immunity was abolished in mice treated to eliminate IgE from the blood. We therefore concluded that IgE and eosinophils are required for adaptive protective immunity to larval O. volvulus in mice.
Fructose metabolism in the human erythrocyte. Phosphorylation to fructose 3-phosphate (1992)

In human erythrocytes, the first step in the metabolism of fructose is generally thought to be phosphorylation to fructose 6-phosphate catalysed by hexokinase. In variance with this assumption, we show here that fructose in these cells is metabolized primarily to fructose 3-phosphate by a specific 3-phosphokinase. This process has an overall estimated Km of 30 mM with respect to extracellular fructose and an apparent Vmax. of 0.6 mumol/h per ml. At a fixed concentration of fructose in the medium, the accumulation of fructose 3-phosphate was linearly dependent on the duration of incubation up to 5 h and was not affected by glucose. Once accumulated, fructose 3-phosphate appears to be degraded and/or relatively slowly metabolized, decreasing by only approximately 30% after a 12 h incubation in a fructose-free medium.
Authentication for Web Services with the Internet Smart Card (2009)

Conventional smart cards according to ISO 7816 exhibit only limited connectivity with IT equipment, as special drivers and special software are required to bridge the gap. The Internet Smart Card offers a new approach to overcome this gap. By providing a communication stack which is directly compatible with popular interfaces, such as USB and TCP/IP, and by introducing an innovative CardToken form factor the Internet Smart Card enables easy-to-use smart card applications. Examples are presented where the Internet Smart Card provides authentication solutions for the internet without the need for complicated installation of driver software and without the need for additional hardware.
Holographic Lactate Sensor (2006)

Measurement of blood l-lactate is used to assess and monitor exercise performance in sports medicine. This report describes the initial development of a holographic sensor, which employs a synthetic receptor, to enable the selective and continuous real-time measurement of l-lactate for eventual in vivo application. Three boronic acid-based receptors have been synthesized, integrated into thin acrylamide hydrogel films, and then subsequently transformed into holographic sensors. Changes in the replay wavelength of the sensors were used to characterize the swelling behavior of the matrix as a function of l-lactate concentration. It was found that the incorporation of 3-acrylamidophenyl boronic acid into an acrylamide hydrogel produced the largest response toward l-lactate. The effects of hydrogel composition, fluctuating l-lactate concentrations, and the response of potential interfering agents to the sensor have been investigated.
Nerve Growth Factor-Induced Cell Cycle Reentry in Newborn Neurons Is Triggered by p38<sup>MAPK</sup>-Dependent E2F4 Phosphorylation (2012)

Cumulative evidence indicates that activation of cyclin D-dependent kinase 4/6 (cdk4/6) represents a major trigger of cell cycle reentry and apoptosis in vertebrate neurons. We show here the existence of another mechanism triggering cell cycle reentry in differentiating chick retinal neurons (DCRNs), based on phosphorylation of E2F4 by p38(MAPK). We demonstrate that the activation of p75(NTR) by nerve growth factor (NGF) induces nuclear p38(MAPK) kinase activity, which leads to Thr phosphorylation and subsequent recruitment of E2F4 to the E2F-responsive cdc2 promoter. Inhibition of p38(MAPK), but not of cdk4/6, specifically prevents NGF-dependent cell cycle reentry and apoptosis in DCRNs. Moreover, a constitutively active form of chick E2F4 (Thr261Glu/Thr263Glu) stimulates G(1)/S transition and apoptosis, even after inhibition of p38(MAPK) activity. In contrast, a dominant-negative E2F4 form (Thr261Ala/Thr263Ala) prevents NGF-induced cell cycle reactivation and cell death in DCRNs. These results indicate that NGF-induced cell cycle reentry in neurons depends on the activation of a novel, cdk4/6-independent pathway that may participate in neurodegeneration.
Image sequence coding using 3‐D structure and motion information (1991)

Abstract Video communications play an important role in an information‐oriented society. A cost‐effective image coding technique capable of rendering high quality video communication services is an important component of any information system. This paper describes an algorithm for image sequence coding using three‐dimensional (3‐D) structure and motion information. Each image is treated as a 2‐D projection of a 3‐D object, with 3‐D information derived and used in the coding scheme. Since the coding scheme considers physical 3‐D information, it provides data compression at the transmitter and improved image quality at the receiver. Furthermore, because the image is represented in a structure‐oriented fashion, it lends itself to image recognition and image understanding. This aids in the realization of high quality communication systems. The proposed algorithm makes extensive use of 3‐D structure and motion information in conjunction with 3‐D motion interpolation and 3‐D motion compensation predictive coding technique to achieve efficient, high quality image sequence coding. A method is described that has 3‐D structure and motion information extraction, and an incremental scheme is presented for stable estimation of 3‐D structure and motion information of rigid as well as non‐rigid bodies.
Printing, Piety, and the People in Italy: The First Thirty Years (1980)

Article Printing, Piety, and the People in Italy: The First Thirty Years was published on December 1, 1980 in the journal Archiv für Reformationsgeschichte - Archive for Reformation History (volume 71, issue jg).
Induction of interleukin 2 production but not methionine adenosyltransferase activity or S-adenosylmethionine turnover in Jurkat T-cells. (1992)

We have recently reported that methionine adenosyltransferase (MAT) in resting human peripheral blood T-cells is primarily present in the form of a precursor which we named lambda. This protein decreases upon cell stimulation, as both MAT activity and the amount of the catalytic alpha/alpha' subunits of the enzyme increase. When resting cells are activated by phytohemagglutinin, the decrease in lambda and increase in alpha/alpha' occurs after interleukin 2 (IL-2) production and before DNA synthesis. The human T-leukemia cell line, Jurkat, is unique in its ability to produce IL-2 in response to exogenous stimuli such as T-cell mitogens and therefore provides a convenient model for studying biochemical reactions involved in T-cell activation. In this study the regulation of MAT activity and S-adenosylmethionine (AdoMet) in resting and activated Jurkat cells was investigated. Here we report that MAT activity in unstimulated Jurkat cells is about 10- and 3-fold higher than the activity in resting and activated peripheral blood mononuclear cells, respectively. Activation of Jurkat cells with phytohemagglutinin resulted in increased IL-2-production, but not an increase in MAT activity. Identical results were obtained using freshly isolated cells from acute lymphoblastic leukemia patients. AdoMet utilization and pool size were approximately 3- and 10-fold higher, respectively, in Jurkat cells compared to peripheral blood mononuclear cells, and both parameters were unaffected by phytohemagglutinin stimulation. Jurkat MAT was determined to be structurally indistinguishable from enzyme from T- or B-leukemia cells but was different from resting, normal T-cells in that it lacked the lambda form. Furthermore, unlike MAT in resting T-cells, the relative amounts of the alpha, alpha', and beta subunits of the enzyme did not change throughout the course of IL-2 induction. We conclude that AdoMet metabolism and MAT activity in Jurkat cells are constitutively high and that induction of IL-2 synthesis in these cells is independent of changes in AdoMet synthesis or turnover. The lack of the lambda form and the difference in MAT regulation between leukemic T-cells and peripheral blood mononuclear cells may be exploited in the design of specific chemotherapeutic agents.
Estimating demosaicing algorithms using image noise variance (2010)

We propose a method for estimating demosaicing algorithms from image noise variance. We show that the noise variance in interpolated pixels becomes smaller than that of directly observed pixels without interpolation. Our method capitalizes on the spatial variation of image noise variance in demosaiced images to estimate the color filter array patterns and demosaicing algorithms. We verify the effectiveness of the proposed method using various images demosaiced with different demosaicing algorithms extensively.
Cooperative DVB-SH satellite broadcasting systems with rotated signal constellations (2015)

In this paper, we study the advantages of cooperation in broadcasting systems from a geosynchronous earth orbit (GEO) satellite to mobile terminals (MTs), achieved through a terrestrial complementary ground station (CGS) with fixed installment, which acts as a relay. Moreover and in the context of the digital video broadcasting-satellite- to-handheld (DVB-SH) standard, the performance improvements offered by the rotated constellations method are investigated, where prior transmission, a phase rotation of the transmitted symbols by a fixed angle is applied followed by a random component interleaver. Turbo codes with soft decision decoding and appropriate random channel interleavers are also considered. We present analytical expressions for the bit log-likelihood ratios (LLRs) that are needed for soft decision decoding at the MT turbo decoder, while the code combining technique is adapted to improve the end-to-end (E2E) performance. Then, we obtain through extensive computer simulations the average bit error probability (ABEP) of quadrature phase-shift keying (QPSK) signals received over pure land-mobile satellite (LMS) and pure CGS links for coding rates 1/3 and 6/7. Moreover, the optimal rotation angles are obtained for both links. E2E ABEP results are then presented assuming cooperation between GEO and CGS, while the power allocation issue is investigated under fixed total transmission power. Our performance evaluation results show that by using the constellation rotation technique, a performance gain can be achieved for high coding rates.
중국의 의료지원체계에 관한 연구 (I) - 관련 법제도를 중심으로 (2017)

Purpose: There is little information about China`s medical service system and health care facilities in Korean medical architecture papers, which is inconvenient for scholars engaged in medical building research and comparison. Futhermore, the transformation of the notion of health and the ascension of the service needs show the lack of medical function, and then make functions of hospital construction are always in the state of dynamic renewal. Therefore, the purpose of this study is to analyze the Chinese medical service system and general hospital related laws and regulations for future research to provide effective analysis of data, and find shortcomings. Methods: This study was conducted by a research on law and regulation of China`s medical service system and general Hospital. Results: At present hospital construction in China is in the period of rapid development and it exposes the layout of medical health facilities is not reasonable and the service does not reach the designated position and so on. Overall, it requires more detailed guidelines to enhance the quality of medical health services. Implications: It is expected that the research of this paper will provide effective reference for future research on Chinese medical architecture system and medical facilities, and can promote and perfect the construction of Chinese medical architecture theory system.
Voltage problems on transmission networks subject to unusual power flow patterns (1991)

Conditions for the existence of a physically acceptable voltage solution in power transmission networks are given, and a sensitivity-based approach for their real-time evaluation is outlined. Theoretical results are illustrated on a simplified Pennsylvania-New Jersey-Maryland model, on which reactive power/voltage problems were reported to exist. On the same system a comparison of the most typical voltage controls is made. Different corrective control actions are compared in the context of their role within a multiple-utility power wheeling operating mode. The study represents an overall attempt to link existing operating voltage problems (frequently economics driven) to the theoretical results necessary for their fundamental understanding and for designing efficient real time system monitoring and control techniques.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
How sea lice from salmon farms may cause wild salmonid declines in Europe and North America and be a threat to fishes elsewhere (2009)

Fishes farmed in sea pens may become infested by parasites from wild fishes and in turn become point sources for parasites. Sea lice, copepods of the family Caligidae, are the best-studied example of this risk. Sea lice are the most significant parasitic pathogen in salmon farming in Europe and the Americas, are estimated to cost the world industry euro300 million a year and may also be pathogenic to wild fishes under natural conditions. Epizootics, characteristically dominated by juvenile (copepodite and chalimus) stages, have repeatedly occurred on juvenile wild salmonids in areas where farms have sea lice infestations, but have not been recorded elsewhere. This paper synthesizes the literature, including modelling studies, to provide an understanding of how one species, the salmon louse, Lepeophtheirus salmonis, can infest wild salmonids from farm sources. Three-dimensional hydrographic models predicted the distribution of the planktonic salmon lice larvae best when they accounted for wind-driven surface currents and larval behaviour. Caligus species can also cause problems on farms and transfer from farms to wild fishes, and this genus is cosmopolitan. Sea lice thus threaten finfish farming worldwide, but with the possible exception of L. salmonis, their host relationships and transmission adaptations are unknown. The increasing evidence that lice from farms can be a significant cause of mortality on nearby wild fish populations provides an additional challenge to controlling lice on the farms and also raises conservation, economic and political issues about how to balance aquaculture and fisheries resource management.