gebhart/patrepeval huggingface dataset:
Decisiones basadas en el conocimiento y en el papel social de la empresa (2007)

LPA therapy is most effective for leg telangiectasias 0.4-3.0 mm in diameter. This LPA technique is significantly improved with the addition of sclerotherapy.
System level investigations of television based bistatic radar (2005)

This dissertation is presented to introduce the reader to the techniques used and the technology of a Television Based Bistatic Radar system.Technology such as this one makes use of a non-cooperative television transmitter as an illuminator for the bistatic radar system investigated.Both technical and theoretical information about the topic will be introduced.The dissertation starts otf with a brief introduction to its stmcture, and evolves into a historical overview of multistatic and bistatic radars.Certain techniques about bistatic radars used in the past will be discussed; their advantages and disadvantages of the various techniques will also be shown.The geometrical design and the various effects of the bistatic radar arrangement will be discussed.A simulator created to plot various SNR patterns over the Western Cape was also developed to estimate the input SNR value received at the receiver.This simulator is flexible in the sense that the transmitter and receiver locations can be arbitrarily placed around the Western Cape.The estimated SNR values for different ranges are then plotted over the mapped area.Not only does the simulator show the SNR plots, it also indicates the coverage area of both the receiver and the transmitter.The target flight path of aircrafts flying into Cape Town can also be included in the simulation.This dissertation will then focus on the actual simulation of the receiver designed for the purpose of airborne target surveillance.These simulations involves actual receiver components used at the system level, with the created television input signal, as well as recorded data.The discussion will then focus on the use of an ordinary pc TV-card which was used as a receiver, whereby measurements were taken for actual targets landing into Cape Town International Airport.These target signals were recorded and analysed.A discussion surrounding this topic was included for the ambiguity analyses of the recorded data.This dissertation is concluded by discussing the conclusions of the research as well as making some recommendations for future \vork which could be done to improvement the measured results for a television based bistatic radar system.
p21 and p27: roles in carcinogenesis and drug resistance (2008)

Human cancers arise from an imbalance of cell growth and cell death. Key proteins that govern this balance are those that mediate the cell cycle. Several different molecular effectors have been identified that tightly regulate specific phases of the cell cycle, including cyclins, cyclin-dependent kinases (CDKs) and CDK inhibitors. Notably, loss of expression or function of two G1-checkpoint CDK inhibitors - p21 (CDKN1A) and p27 (CDKN1B) - has been implicated in the genesis or progression of many human malignancies. Additionally, there is a growing body of evidence suggesting that functional loss of p21 or p27 can mediate a drug-resistance phenotype. However, reports in the literature have also suggested p21 and p27 can promote tumours, indicating a paradoxical effect. Here, we review historic and recent studies of these two CDK inhibitors, including their identification, function, importance to carcinogenesis and finally their roles in drug resistance.
Index system and separability of constant weight Gray codes (1991)

A number system is developed for the conversion of natural numbers to the codewords of the Gray code G(n,k) of length n and weight k, and vice versa. The focus is on the subcode G(n,k) of G(n) consisting of those words of G(n) with precisely k 1-bits, 0<k<n. This code is called the constant weight Gray code of length n and weight k. As an application sharp lower and upper bounds are derived for the value of mod i-j mod , where i and j are indices of codewords g/sub i/ and g/sub j/ of G(n,k) such that they differ in precisely 2m bits.<<ETX>>
Dinitrogen Cleavage by a Diniobium Tetrahydride Complex: Formation of a Nitride and Its Conversion into Imide Species (2007)

Breaking up isn't hard to do: When a solution of the hydride complex [K(dme)]2[{Nb}2(μ-H)4] (see scheme) is exposed to N2, the nitride complex [K(thf)2]2[{Nb}2(μ-N)2] and H2 form with concomitant cleavage of the dinitrogen triple bond. The nitride ligands undergo alkylation with MeI in a stepwise fashion, resulting in formation of a bis(imide) complex via a nitride imide complex.
Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity (2005)

Compound 3 (BMS-536924), a novel small-molecule inhibitor of the insulin-like growth factor receptor kinase with equal potency against the insulin receptor is described. The in vitro and in vivo biological activity of this interesting compound is also reported.
Bridging Leadership and Culture: A Theoretical Consideration of Transformational Leadership and Collectivistic Cultures (1995)

Although transformational leadership has gained increased attention by management researchers as a new paradigm for understanding leadership in organizations, little research effort has focused upon the linkage between transformational leadership and collectivistic cultures. Nor has a theoretical consideration been offered to elucidate the emergence of transformational leadership outside of the United States, particularly in collectivistic cultures. To address this theoretical shortcoming, this paper presents several characteristics of collectivistic cultures as preconditions for facilitating the transformational leaders' effectiveness. Specifically, four characteristics of transformational leadership suggested by Bass and his colleagues are linked to collectivism for describing a conceptual bridge between these two distinct paradigms.
Complex master-slave for long axial range swept-source optical coherence tomography (2018)

International audience
Temperature Dependence of Neutron-Gamma Discrimination Based on Pulse Shape Discrimination Technique in a ${\rm Ce:LiCaAlF}_{6}$ Scintillator (2013)

LiCaAlF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sub> scintillators are one of the attractive scintillators for neutron detection. To reduce the effect on gamma-rays, the Ce doped LiCaAlF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sub> scintillators can discriminate the neutron and gamma-ray events based on the pulse shape discrimination technique. To apply the scintillators for the oil logging, the high temperature characteristics must be investigated. In this paper, the temperature dependence of the neutron-gamma discrimination based on pulse shape discrimination technique in the Ce:LiCaAlF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sub> scintillator is investigated as one of the high temperature characteristics. The property of pulse shape discrimination in the Ce:LiCaAlF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sub> has small temperature dependence ranging from 25 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C to 150 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C. We concluded that the Ce:LiCaAlF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sub> scintillators can discriminate neutron and gamma-ray events under high temperature condition up to 150 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C .
Effective method for encapsulation of titanium dioxide and other solids by gamma-ray-induced polymerisation (1991)

Radiation-induced polymerisation of various monomers, using γ-rays, is a very effective method for encapsulating titanium dioxide and other solids. Preferential polymerisation occurs on the surfaces when the system is suspended in a solution of the monomers in CF2ClCFCl2. Addition of a proportion of methacrylic acid is beneficial to promote polymerisation on the surface, which appears to arise from initial adsorption, followed by initiation.
A 32 Gb/s, 201 mW, MZM/EAM Cascode Push–Pull CML Driver in 65 nm CMOS (2017)

This brief presents a 32 Gb/s driver for a Mach-Zehnder modulator (MZM) and an electro-absorption modulator (EAM). A push-pull current-mode logic driver is chosen to achieve a better power efficiency and a large voltage swing. A double cascode with thin oxide transistors is employed to mitigate the over-voltage stress associated with a large output voltage swing. At the same time, shunt-peaking inductors are incorporated in a compact way to extend the bandwidth and to have a flat group delay. The proposed driver has been fabricated using 65 nm CMOS technology with an active area of 0.086 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The electrical measurement result shows that the driver exhibits a differential output swing of 4 V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">pp</sub> at 10 Gb/s. The measured extinction ratios of the driver using the MZM and EAM are 4.53 dB and 4.17 dB, respectively, at 32 Gb/s. The power consumption is 201 mW at 32 Gb/s, which corresponds to an energy efficiency of 6.28 mW/Gb/s.
Synthetic studies on lignans and related compounds. VII. Synthesis of .BETA.-apoplicatitoxin trimethyl ether. (1978)

β-Apoplicatitoxin trimethyl ether (8) was synthesized by selective photocyclization of a dibenzylidenebutyrolactone (6). The photocyclization was preliminarily examined in various solvents by use of a model compound (1), and the total yield of resulting isomeric β-apolignans (2a and 2b) and the ratio of 2a/2b were shown to increase with increasing solvent polarity.
Alexander Innes (1953)

Alexander Innes Get access C. S. A. Dobson C. S. A. Dobson Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume CXCVIII, Issue jun, 1 June 1953, Page 269, https://doi.org/10.1093/nq/CXCVIII.jun.269 Published: 01 June 1953
ESG Investments: Filtering versus Machine Learning Approaches (2021)

We designed a machine learning algorithm that identifies patterns between ESG profiles and financial performances for companies in a large investment universe. The algorithm consists of regularly updated sets of rules that map regions into the high-dimensional space of ESG features to excess return predictions. The final aggregated predictions are transformed into scores which allow us to design simple strategies that screen the investment universe for stocks with positive scores. By linking the ESG features with financial performances in a non-linear way, our strategy based upon our machine learning algorithm turns out to be an efficient stock picking tool, which outperforms classic strategies that screen stocks according to their ESG ratings, as the popular best-in-class approach. Our paper brings new ideas in the growing field of financial literature that investigates the links between ESG behavior and the economy. We show indeed that there is clearly some form of alpha in the ESG profile of a company, but that this alpha can be accessed only with powerful, non-linear techniques such as machine learning.
Modern Grid Initiative Distribution Taxonomy (Final Report) (2008)

This is the final report for the development of a toxonomy of prototypical electrical distribution feeders. Two of the primary goals of the Department of Energy's (DOE) Modern Grid Initiative (MGI) are 'to accelerate the modernization of our nation's electricity grid' and to 'support demonstrations of systems of key technologies that can serve as the foundation for an integrated, modern power grid'. A key component to the realization of these goals is the effective implementation of new, as well as existing, 'smart grid technologies'. Possibly the largest barrier that has been identified in the deployment of smart grid technologies is the inability to evaluate how their deployment will affect the electricity infrastructure, both locally and on a regional scale. The inability to evaluate the impacts of these technologies is primarily due to the lack of detailed electrical distribution feeder information. While detailed distribution feeder information does reside with the various distribution utilities, there is no central repository of information that can be openly accessed. The role of Pacific Northwest National Laboratory (PNNL) in the MGI for FY08 was to collect distribution feeder models, in the SynerGEE{reg_sign} format, from electric utilities around the nation so that they could be analyzed to identify regional differences in feeder design and operation. Based on this analysis PNNL developed a taxonomy of 24 prototypical feeder models in the GridLAB-D simulations environment that contain the fundamental characteristics of non-urban core, radial distribution feeders from the various regions of the U.S. Weighting factors for these feeders are also presented so that they can be used to generate a representative sample for various regions within the United States. The final product presented in this report is a toolset that enables the evaluation of new smart grid technologies, with the ability to aggregate their effects to regional and national levels. The distribution feeder models presented in this report are based on actual utility models but do not contain any proprietary or system specific information. As a result, the models discussed in this report can be openly distributed to industry, academia, or any interested entity, in order to facilitate the ability to evaluate smart grid technologies.
Energy-efficient target coverage in wireless sensor networks (2005)

A critical aspect of applications with wireless sensor networks is network lifetime. Power-constrained wireless sensor networks are usable as long as they can communicate sensed data to a processing node. Sensing and communications consume energy, therefore judicious power management and sensor scheduling can effectively extend network lifetime. To cover a set of targets with known locations when ground access in the remote area is prohibited, one solution is to deploy the sensors remotely, from an aircraft. The lack of precise sensor placement is compensated by a large sensor population deployed in the drop zone, that would improve the probability of target coverage. The data collected from the sensors is sent to a central node (e.g. cluster head) for processing. In this paper we propose un efficient method to extend the sensor network life time by organizing the sensors into a maximal number of set covers that are activated successively. Only the sensors from the current active set are responsible for monitoring all targets and for transmitting the collected data, while all other nodes are in a low-energy sleep mode. By allowing sensors to participate in multiple sets, our problem formulation increases the network lifetime compared with related work [M. Cardei et al], that has the additional requirements of sensor sets being disjoint and operating equal time intervals. In this paper we model the solution as the maximum set covers problem and design two heuristics that efficiently compute the sets, using linear programming and a greedy approach. Simulation results are presented to verify our approaches.
Parameters of Mycoplasma pneumoniae infection in Syrian hamsters (1988)

An animal model for evaluating the potency of Mycoplasma pneumoniae vaccines was developed with hamsters. Factors that influence hamster infection by M. pneumoniae were defined, and parameters for assessment of intensity of pulmonary disease were established. Colonization of hamster lungs was determined by culture, and intensity of lung disease was assessed histopathologically and expressed numerically as a lung pathological score. Intratracheal inoculation of the challenge was superior to the intranasal or aerosol route for inducing a consistent degree of lung disease. A challenge dose of 10(6) CFU inoculated intratracheally produced lung colonization and significant reproducible lung pathological scores in essentially all unvaccinated animals. The peak of infection, as determined by these criteria, was at about 2 weeks after challenge. Animals over 6 weeks of age were preferable for the test, since younger animals exhibited a lower lung pathological score even though they showed the same degree of lung colonization. The hamster assay developed provides a dependable experimental system for testing the protective potency of M. pneumoniae vaccines.
Fault-tolerant clock synchronization techniques for avionics systems (1988)

This paper examines six provably correct fault-tolerant clock synchronization algorithms. These algorithms are all presented in the same notation to enable easier comprehension and comparison. The advantages and disadvantages of the different techniques are examined and issues related to the implementation of these algorithms are discussed. The paper argues for the use of such algorithms in life-critical applications.
Trace visualization and analysis tool for supervisory control systems (2002)

Much time has been taken to examine supervisory control systems in their software engineering processes. Trace analysis has been one of the effective methods in proceeding with this examination since traces represent the actual flow of events in the systems. We have developed a trace analysis tool to help us with system understanding. The tool analyzes traces and extracts the kind of event, when it completed and which tasks it involved. It also visualizes the flow of events and the interaction that had taken place between tasks on the screen. The typical feature of the tool is to identify frequent event patterns such as periodic patterns by extending the algorithm for text data compression. We applied the tool to the engineering process of rail traffic control systems, and found the tool was effective in reducing the time for simplifying understanding of the dynamic behaviours of the system and finding problem areas.
Prolonged remission maintenance in acute myeloid leukaemia. (1977)

Twenty-five patients with acute myeloid leukaemia were treated with three quadruple drug combinations in predetermined rotation: TRAP (thioguanine, daunorubicin, cytarabine, prednisolone); COAP (cyclophosphamide, vincristine, cytarabine, prednisolone); and POMP (prednisolone, vincristine, methotrexate, mercaptopurine). Fifteen patients (60%) achieved complete remission and five (20%) partial remission. For maintenance, five-day courses of drugs were administered every 14 to 21 days and doses were increased to tolerance. The median length of complete remission was 66 weeks. In eight patients remission maintenance treatment was discontinued and some remained in complete remission for over two years. In this series the remission induction rate was comparable with that reported for other regimens and complete remission lasted longer with this intensive maintenance regimen than with others. Nevertheless, the TRAP programme must still be regarded as only palliative treatment for acute myeloid leukaemia.
Autonomous Object Manipulation Using a Soft Planar Grasping Manipulator (2015)

This article presents the development of an autonomous motion planning algorithm for a soft planar grasping manipulator capable of grasp-and-place operations by encapsulation with uncertainty in the position and shape of the object. The end effector of the soft manipulator is fabricated in one piece without weakening seams using lost-wax casting instead of the commonly used multilayer lamination process. The soft manipulation system can grasp randomly positioned objects within its reachable envelope and move them to a desired location without human intervention. The autonomous planning system leverages the compliance and continuum bending of the soft grasping manipulator to achieve repeatable grasps in the presence of uncertainty. A suite of experiments is presented that demonstrates the system's capabilities.
3D POSE ESTIMATION FROM SILHOUETTES IN CYCLIC ACTIVITIES ENCODED BY A DENSE GAUSSIANS MIXTURE MODEL (2010)

This paper presents a system for 3D Pose estimation of cyclic activities (e.g. walking, jogging). Principal Component Analysis is used to compress the high dimensional space of poses. Human activities are encoded by Hidden Markov Models, overlaid on Gaussian Mixture Models. A generative approach based on the Annealed Particle Filter is used to estimate poses from silhouettes derived by a monocular camera. Experimental results indicate the value of the proposed Dense Gaussian Mixture Model when initialised by a gait cycle. 1
Agreement of Owren and Quick Prothrombin Times: Effects of Citrate and Calcium Concentrations and International Sensitivity Index Correction (2001)

The prothrombin time (PT) is commonly measured by either the “Quick method”, which is based on the technique described by Quick and co-workers in 1935 (1)(2), or by the Owren method (3) (combined thromboplastin reagent). The latter is the predominant approach used in the Nordic countries, Benelux, and Japan. These two methods are rarely mentioned or noted in the scientific literature (4)(5), and more attention is paid to the thromboplastin in the reagent and to its origin (6)(7).

The Owren method is sensitive to coagulation factors II, VII, and X. Fibrinogen (factor I) and factor V are in the reagent. The Quick method is affected by deficiencies of fibrinogen and factors II, V, VII, and X. Both methods are suitable for the control of anticoagulant treatment. The most important technical difference between the two is the sample volume in the reaction mixture: 5% in the Owren method, and 33% in the Quick method. This has the effect of making the coagulation reaction in the Quick method more sensitive to many preanalytical variables, e.g., citrate concentration in the sample (8)(9). The small sample volume in the reaction mixture with the Owren method makes it possible to use even EDTA plasma (10).

The International Normalized Ratio (INR) is recommended to harmonize PT results for oral anticoagulant therapy (11). The recommendation conforms with those made by WHO using reference thromboplastins (12). Regardless of the reagent, instrument, or method used, the results should be the same when the INR system is used.

Because these two major PT methods have not previously been compared, the aim of this study was to compare the PT results obtained with two Owren reagents as INR units in samples containing 0.129 mol/L (3.8%) citrate solution and to compare the …
EphA5 protein, a potential marker for distinguishing histological grade and prognosis in ovarian serous carcinoma (2016)

Our results show that EphA5 may be a potential biomarker for distinguishing high-and low-grade ovarian serous carcinoma and a potential prognostic marker.