gebhart/patrepeval huggingface dataset:
Non-iterative impulse response shortening method for system latency reduction (2017)

In this paper we present a non-iterative impulse response shortening method aiming to reduce the latency of a system. Our method exploits that smoothing the frequency-domain response generally leads to a shorter time-domain response. The method is simple to implement and has a computational complexity that is significantly lower than that of competing methods. Yet it achieves good performance. It can be used for applications involving system identification such as blind source separation (BSS), cross-talk cancellation and channel equalization. Our experimental results confirm the effectiveness of the method, demonstrating the benefit of the approach in the BSS and cross-talk cancelling applications.
Shear Reversible Alumina Gels for Direct Writing (2014)

Phase diagram of alumina sol has been investigated, wherein a unique region of shear reversible gels has been discovered. In this region, rapid transformation from gel to sol was observed, where the viscosity shows a sudden drop by six orders of magnitude on application of shear stress. The sol to gel transformation was observed to depend on the composition of the sol and could be tuned in the range of few seconds to hours. These gels are suitable for fabricating complex three‐dimensional structures using advanced technology of direct write and ink‐jet printing.
CD200R1 Agonist Attenuates Mechanisms of Chronic Disease in a Murine Model of Multiple Sclerosis (2010)

To assess the effects and mechanisms of a CD200R1 agonist administered during the progressive stage of a multiple sclerosis model, we administered CD200R1 agonist (CD200Fc) or control IgG2a during the chronic phase of disease (days 10-30) in mice with experimental autoimmune encephalomyelitis (EAE), induced using myelin oligodendrocyte glycoprotein peptide 35-55 (MOG35-55) peptide. We found that administration of CD200Fc during the chronic stages of EAE reduced disease severity, demyelination, and axonal damage, through the modulation of several key disease mechanisms. CD200Fc treatment suppressed macrophage and microglial accumulation within the CNS, in part through downregulation of adhesion molecules VLA-4 and LFA-1, which are necessary for macrophage migration. Additionally, expression of activation markers MHC-II and CD80 and production of proinflammatory cytokines IL-6, tumor necrosis factor-alpha, and nitric oxide by CD11b(+) cells were decreased in both the spleen and CNS in CD200Fc-treated animals. Antigen-presenting cell function in the spleen and CNS was suppressed in CD200Fc-treated mice, but there were no significant alterations on T cell activation or phenotype. CD200Fc increased apoptosis of CD11b(+) cells but not astrocytes. In contrast, addition of CD200Fc treatment protected oligodendrocytes from apoptosis in vitro and in vivo. Our results demonstrate that CD200R1 agonists modulate both myeloid- and non-myeloid-related mechanisms of chronic disease in the EAE model and may be effective in the treatment of progressive multiple sclerosis and other neurodegenerative diseases.
Ultrasonographic Features of Focal Xanthogranulomatous Pyelonephritis. (2003)

Objective. To analyze the ultrasonographic features of focal xanthogranulomatous pyelonephritis. Methods. Ultrasonographic features of 15 patients with pathologically proved focal xanthogranulomatous pyelonephritis were retrospectively analyzed by 2 radiologists who reached a consensus, in terms of the location, margin, size, and echo texture of the mass, associated calculi, lymphadenopathy, or local extension, in comparison with computed tomographic and clinical findings. Results. At ultrasonography, 12 (80%) of 15 masses were well circumscribed. The maximal sizes of the masses ranged from 2.5 to 5.8 (mean, 3.8) cm. Thirteen solid masses (87%) were hyperechoic (n = 7), hypoechoic (n = 4), or isoechoic (n = 4) to the renal cortex, and the preoperative diagnosis was either renal cell carcinoma (n = 11) or Wilms tumor (n = 2). The preoperative diagnosis of the other 2 cystic lesions (13%) was renal abscess. Renal calculi were found in 1 case, but lymphadenopathy or local extension was not depicted. Clinical inflammatory signs were found in 11 of 15 patients. Conclusions. There were no specific ultrasonographic features that allow for the distinction between focal xanthogranulomatous pyelonephritis and renal tumors or abscesses. Focal xanthogranulomatous pyelonephritis should be considered when there are clinical signs of infection or inflammation and a focal solid mass is seen on ultrasonography.
Analysis of encoding efficiency in MR imaging of velocity magnitude and direction (1992)

The efficiency of balanced versus unbalanced techniques for phase-angle-based velocity magnitude and direction imaging is investigated. Methods having balanced flow-encoding gradients (gradients in positive and negative directions with a zero center of gravity) are compared with unbalanced methods. For three-dimensional imaging, a currently used balanced method is the six-point technique having opposed gradients pairs for each orthogonal direction. A currently used unbalanced method is a four-point null technique which has three orthogonal gradients and an additional acquisition having no specific flow encoding to correct the baseline (null) phase. In the gradient-limited case of slow flow and perfusion, the balanced method is predicted to have higher velocity magnitude-to-noise ratio per time (SNRV) by a factor of 1.63, with similar results for velocity direction. In the wraparound-limited case of faster flows and motions, similar results are found when a null acquisition is added to the balanced method. This results in a seven-point balanced method having an SNRV 1.51 times that of the four-point unbalanced method. If null phases are within the [-pi/2,pi/2] interval, this additional null acquisition is unnecessary. Other four-point methods are also considered. These results indicate that, in general, balanced methods have advantages over unbalanced methods for velocity imaging.
Microdeflectometry—a novel tool to acquire three-dimensional microtopography with nanometer height resolution (2008)

We introduce "microdeflectometry," a novel technique for measuring the microtopography of specular surfaces. The primary data are the local slope of the surface under test. Measuring the slope instead of the height implies high information efficiency and extreme sensitivity to local shape irregularities. The lateral resolution can be better than 1 microm, whereas the resulting height resolution is in the range of 1nm. Microdeflectometry can be supplemented by methods to expand the depth of field, with the potential to provide quantitative 3D imaging with scanning-electron-microscope-like features.
Graphical Method for Analysis of Ultrahigh-Resolution Broadband Mass Spectra of Natural Organic Matter, the Van Krevelen Diagram (2003)

Electrospray ionization mass spectrometry (ESI-MS) is becoming an important tool in the study of natural organic matter (NOM) at the molecular level. Ultrahigh-resolution ESI-MS analyses of NOM often produce very complicated spectra; therefore, visual presentation and structural interpretations of the spectra are difficult. To meet this analytical challenge, we herein propose and demonstrate an approach using the van Krevelen diagram. With this approach, complicated mass spectra can be visualized in a way that allows for (1) possible reaction pathways to be identified and presented, and (2) qualitative analyses on major classes of compounds that comprise ultrahigh-resolution spectra. The qualitative analyses are in a good agreement with results obtained from analyses by other analytical techniques. Additionally, the van Krevelen diagram can be expanded to a 3D plot by using peak intensities or relative intensities as the z-axis. The 3D van Krevelen diagram allows for an evaluation of the relative significance of structurally related compounds. The 3D plot can also be a useful tool for compositional differentiation among samples.
Size of Batholiths (1931)

Research Article| September 30, 1931 Size of Batholiths ALFRED C. LANE ALFRED C. LANE Search for other works by this author on: GSW Google Scholar Author and Article Information ALFRED C. LANE Publisher: Geological Society of America Received: 06 Jan 1931 First Online: 02 Mar 2017 Online Issn: 1943-2674 Print Issn: 0016-7606 © 1931 Geological Society of America GSA Bulletin (1931) 42 (3): 813–824. https://doi.org/10.1130/GSAB-42-813 Article history Received: 06 Jan 1931 First Online: 02 Mar 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation ALFRED C. LANE; Size of Batholiths. GSA Bulletin 1931;; 42 (3): 813–824. doi: https://doi.org/10.1130/GSAB-42-813 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyGSA Bulletin Search Advanced Search Abstract Conventional Sections and MapsIn cross-sections showing granite batholiths,2 it is customary to depict them as extending down as far as the section goes, bounded by rather steep sides and with no known bottom, which is in accord with the definition of a batholith, but the question may be asked; how far is this due to those limitations of drawing which compel us, in showing what we know, to show also more than we know?We find on geologic maps very large areas of a single color which indicate granite batholiths. If these were indeed all uniform granite they might be conceived as extensive, flat-lying sills of which only the top had been exposed by erosion, but it would be equally natural, indeed almost compulsory, to conceive them as sections of a uniform layer of granite “sial,” supposed to underlie the continents and transmit earthquake waves with a velocity of . . . This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Microbial Hydrolysis of Organic Nitriles and Amides (2007)

Nitrile-hydrating enzymes produced by bacteria and fungi catalyse the conversion of a large number of chemically diverse nitriles, including many economically important compounds used industrially for chemical synthesis of amides and acids. This paper presents data on two new, highly different nitrile-hydrolysing enzymes which were isolated in connection with our studies on enzymic nitrile transformations. Particular attention was paid to the enzymes' substrate specificities and sensitivity to substrate/product inhibition. One of our microbial isolates was a Rhodococcus sp. (strain CH5). This strain produces a constitutive hydratase that has a broad substrate spectrum, including aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles. It also produces a constitutive amidase of equally low substrate specificity. The hydratase/amidase system catalysed the hydrolysis of D,L-aminonitriles into racemic mixtures of amino acids. Strain CH5 is able to produce high concentrations of malonic acid monoamide from malononitrile and malonamide. The other isolate, Alcaligenes sp. (strain I4), can convert high concentrations of cyanoacetate into malonic acid, presumably by means of an aliphatic nitrilase that is specific for cyanoacetate. Enzyme kinetic experiments have shown that this enzyme is very resistant to both substrate and product inhibition.
Reduction of noise and distortion in amplifiers using adaptive cancellation (1994)

Application of adaptive cancellation techniques to feed-forward networks for amplifier linearization is discussed. Results of a test showing over 25 dB reduction in third order intermodulation products are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Encountered‐type haptic display for large VR environment using per‐plane reachability maps (2018)

Abstract We show a novel encountered‐type haptic system, H‐Wall, to enable haptic feedback using a manipulator of seven degrees of freedom suitable for simulating indoor virtual reality environments, which are characterized and confined by a set of vertical walls and revolving doors. At runtime, our system tracks hand motion using a red–green–blue depth sensor and locates its configuration. Then, the robotic manipulator plans a trajectory for the end effector, attached to a rectangular rigid board, to make contact with the hand to deliver a sense of touch as long as the perceived hand contact force is substantial. The force feedback is generated in a passive sense for static walls that the rigid board, corresponding to a vertical wall, holds its position as long as the perceived hand contact force is substantial. For a revolving door, the force feedback is generated in an active sense based on impedance control. In order to address the issue of limited workspace, we also propose a new reachability map, called per‐plane reachability map , that is optimized to answer whether passive haptic feedback can be generated by a manipulator when the user touches a vertical wall at a given orientation. We successfully demonstrate our system to provide an illusion to the user in a virtual environment with touch sensation to the surrounding environment.
In vivo CAMPATH-1 followed by T cell-depleted bone marrow transplantation: a potential new mode of therapy for hepatitis-associated severe aplastic anemia (SAA). (1996)

Bone marrow transplantation (BMT) has been previously reported as a successful mode of treatment for hepatitis B and associated severe aplastic anemia (SAA). Non-A, non-B, non-C hepatitis is one of the causes of SAA. The etiology of SAA caused by non-A, non-B, non-C hepatitis is unknown. There is evidence that the immune response and, specifically, T cells and monocytes have a major role in both HCV- and HBV-induced liver damage. The liver damage caused by non-A, non-B, non-C hepatitis may be associated with similar mechanisms. We describe an 8-year-old girl who developed SAA post-non-A, non-B, non-C hepatitis infection. She was treated by in vivo CAMPATH-1G antibodies followed by T cell depleted HLA-matched BMT and cyclosporin A, resulting in gradual improvement and almost normalization of liver function. We suggest that treatment with CAMPATH-1G followed by T cell-depleted BMT and cyclosporin A could be a novel mode of therapy for viral non-A, non-B, non-C hepatitis-induced liver damage and associated SAA.
북한 사회복지 연구 동향 (2011)

본 연구의 목적은 남한 학계에서 연구되었던 북한 사회복지에 대한 연구동향 파악을 통해, 북한 사회복지 연구에 대한 한계고찰 및 발전방안을 제시하는 것이다. 이를 위해 북한 사회복지와 관련된 99개(1972년-2009년)의 학술논문을 대상으로 하여, 체제관점, 방법론·인식론, 분석내용, 분석범위, 분석방법, 원전인용이라는 6가지 분석기준을 통해 실증 분석하였다. 분석결과, 체제 내 변화 관점은 단 한 편도 찾아볼 수 없었다. 내재적-비판적 접근이 56.6%, 외재적-전체주의적 접근이 43.4%였다. 제도연구가 91.9%로 가장 많았고, 현실(실천)연구가 6.1%, 이념적 차원의 글은 2.0%로 가장 적었다. 거시남북한 연구가 63.6%로 가장 많았고, 그 뒤를 이어 거시북한, 미시북한, 미시남북한의 순이었다. 질적문헌연구가 54.5%로 가장 많았고, 조합전략연구, 양적실태연구의 순이었다. 남북비교가 82.4%로 압도적이었으며, 비교사회주의 연구는 8.8%에 불과하였다. 북한원전을 단 하나도 인용하지 않는 연구들이 66.7%로 가장 많았고, 원전중심인용 연구는 4.0%에 불과하였다. 이러한 결과를 바탕으로 한 발전 방안을 제시해 보았다. 첫째, ``체제 내 변화`` 관점을 통한 균형적 시각 마련, 둘째, 외재적-전체주의적 접근의 지양, 내재적-비판적 접근의 강화, 셋째, 이념연구의 발견, 제도연구의 지속적 확장, 현실(실천)연구에서 대상의 다양화, 넷째, 미시연구 강화, 다섯째, 양적실태연구의 강화, 종합전략연구의 모색, 비교사회주의 연구의 확대, 여섯째, 원전중심의 북한 사회복지 연구가 요청된다.
Alzheimer's disease drug development pipeline: 2019 (2019)

Drug development continues robustly at all phases despite setbacks in several programs in the recent past. Continuing unmet needs require a commitment to growing and accelerating the pipeline.
Gemini surfactant for fluorescent and stable quantum dots in aqueous solution (2007)

Highly fluorescent and stable CdSe/ZnS core/shell quantum dots (QDs) coated with gemini surfactant are successfully synthesized in aqueous media. Analyses of luminescence spectrometry, ultraviolet–visible (UV–vis) spectrophotometry, and transmission electron micrographs (TEMs) indicate that the water-soluble QDs are monodisperse and have a luminescence enhancement compared with the original hydrophobic QDs. The water-soluble QDs coated with gemini surfactant are shown to be biocompatible, photostable, and have been proven to be suitable for live cell imaging.
MICL controls inflammation in rheumatoid arthritis (2015)

MICL plays an essential role in regulating inflammation during arthritis and is an autoantigen in a subset of patients with RA. These data suggest an entirely new mechanism underlying RA pathogenesis, whereby the threshold of myeloid cell activation can be modulated by autoantibodies that bind to cell membrane-expressed inhibitory receptors.
Assessing primitives performance on multi-stage execution (2018)

Virtual machines, besides the interpreter and just-in-time compiler optimization facilities, also include a set of primitive operations that the client language can use. Some of these are essential and cannot be performed in any other way. Others are optional: they can be expressed in the client language but are often implemented in the virtual machine to improve performance when the just-in-time compiler is unable to do so (start-up performance, speculative optimizations not implemented or not mature enough, etc.).
Poly(amino acid)s micelle-mediated assembly of magnetite nanoparticles for ultra-sensitive long-term MR imaging of tumors (2010)

Micelles composed of a novel weakly cationic poly(amino acid)s shell and clustered magnetite nanoparticles as a core were prepared and evaluated as a potent MR imaging contrast agent based on their superior physicochemical and magnetic properties and the effective MR imaging of cancer in vitro and in vivo.
Variable block-sized vector quantization of grayscale images with unconstrained tiling (2002)

The design and performance evaluation of a variable block-sized vector quantizer with unconstrained tiling (UTVQ) is discussed. The coder segments the input image into an unconstrained tiling of variously-sized, nonoverlapping rectangular regions, each of which is then coded with a vector quantizer. UTVQ is compared with the more constrained quadtree vector quantizer (QTVQ) approach. A transmission scheme which reduces the overhead required to convey UTVQ segmentation geometry is developed. Several UTVQ segmentation strategies are explored, and mean-residual codebooks with appropriate side-stream compression techniques are developed. The projected rate and rate-distortion figures indicate that the UTVQ system outperforms the QTVQ system under typical conditions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Rapid volumetric method for the determination of lead (1930)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRapid volumetric method for the determination of leadR. C. WileyCite this: Ind. Eng. Chem. Anal. Ed. 1930, 2, 1, 124–126Publication Date (Print):January 1, 1930Publication History Published online1 May 2002Published inissue 1 January 1930https://pubs.acs.org/doi/10.1021/ac50069a051https://doi.org/10.1021/ac50069a051research-articleACS PublicationsRequest reuse permissionsArticle Views58Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Identification of Premature Ovarian Failure Patients with Underlying Autoimmunity (2000)

Although known causes of premature ovarian failure (POF) include X chromosome deletions, radiation and chemotherapy, and genetic defects of the gonadotropin hormones or receptors, at least one third to one half of cases remain idiopathic. A significant proportion of patients with apparently idiopathic POF have some evidence for an autoimmune etiology. However, the only gold standard for detecting autoimmune causes of immune ovarian destruction has been invasive ovarian biopsy. Serum antibodies to ovarian and other self-tissue have been described in up to one third of women with POF, but the tests are not well standardized, not well correlated with ovarian histology, and highly variable. Recently, specific defects of expression of cell surface markers on peripheral blood lymphocytes have been shown to identify, in population-based studies, individuals destined to develop autoimmune pancreatic destruction and type I diabetes mellitus, even before any other evidence of autoimmunity. We, therefore, sought to test the ability of cell surface marker expression in women with POF to identify autoimmune defects. Seventeen women with POF, 11 of whom had positive antibody titers to ovary, thyroid, or antinuclear antibody, were studied on at least two occasions and compared in blinded fashion with normal controls and patients with autoimmune type I diabetes mellitus. The most useful marker for identifying autoimmunity was the surface density of conformationally correct HLA class I molecules on macrophages, a structure essential for T cell education. Using this marker, 7 of the 9 patients with autoantibodies and 3 of the 8 patients without autoantibodies were identified as having evidence of a defect in self-antigen presentation similar to that of type I diabetics (chi-square, p = 0.03). Subsequent testing identified antismooth muscle antibodies in 1 of the women with a defect of HLA class I molecules but no previously identified autoimmunity. In addition, there were increased numbers of CD8 T cells in both autoimmune POF and insulin-dependent diabetes mellitus (IDDM) patients. Exclusive to POF patients was a statistically significant increase in CD8 density on T cells. This was most prominent in POF patients with an underlying autoimmune etiology. These data further support a role for autoimmunity in POF patients and suggest that the further development of cell surface markers in combination with other diagnostic tests could result in diagnosis before the development of complete ovarian failure. The possibility for disease-specific therapy to prevent further autoimmune ovarian damage in selected POF patients is also envisioned.
Spectrophotometric Quantification of Glycine in Serum and Urine (1973)

Abstract A method for quantitative determination of glycine in serum and urine, involving degradation to formaldehyde with chloramine-T and subsequent measurement by the Hantzsch reaction or chromotropic acid, has been evaluated and modified. The inhibitory effect of some physiological constituents on the analysis is pointed out. We recommend that samples be purified by passage through a column of ion-exchange resin before analysis. Results for urinary glycine obtained by a single-column amino acid analyzer system compare very favorably with those obtained by the proposed spectrophotometric method. Values for free and total glycine and for glycine/creatinine ratios in the urine of a group of infants are presented along with revised data on the concentration of free glycine in serum.