gebhart/patrepeval huggingface dataset:
Explorations in fixed and adaptive resolution at GE and SURC (1976)

This paper recounts the invention and development of adaptive processing at General Electric and the Syracuse University Research Corporation, giving heuristic explanations of the behavior of adaptive systems and discussing the relation between fixed and adaptive resolution.
Current status of cow dung as a bioresource for sustainable development (2016)

Cow dung, an excreta of bovine animal, is a cheap and easily available bioresource on our planet. Many traditional uses of cow dung such as burning as fuel, mosquito repellent and as cleansing agent are already known in India. Cow dung harbours a diverse group of microorganisms that may be beneficial to humans due to their ability to produce a range of metabolites. Along with the production of novel chemicals, many cow dung microorganisms have shown natural ability to increase soil fertility through phosphate solubilisation. Nowadays, there is an increasing research interest in developing the applications of cow dung microorganisms for biofuel production and management of environmental pollutants. This review focuses on recent findings being made on cow dung that could be harnessed for usage in different areas such as medicine, agriculture and industry.
Purification and preliminary X‐ray crystallographic studies of recombinant L‐ribulose‐5‐phosphate 4‐epimerase from <i>escherichia coli</i> (1995)

The araD gene from Escherichia coli, coding for L-ribulose-5-phosphate 4-epimerase, was overexpressed and the resulting enzyme was purified to homogeneity. Crystals of L-ribulose-5-phosphate 4-epimerase, obtained with 4.0 M sodium formate as precipitant, belong to space group P4212 with unit cell dimensions a = b = 107.8 A and c = 281.4 A and diffract to at least 2.2 A resolution. Density measurements of these crystals are consistent with eight subunits in the asymmetric unit.
Minimal transient switching of capacitors (1993)

Capacitor banks are used to compensate the reactive power demand of large commercial and industrial loads. When used to switch capacitor banks mechanical breakers generate large current transients. These transients may cause serious system disturbances, premature wear of the breaker contacts and, possibly, shorten the life of the capacitors. While thyristor switches are not new and industry has successfully used them to obtain transient-free switching of capacitor banks, there are very few papers describing this application. This paper tries to fill the void and presents a comparative study of various three-phase configurations of semiconductor switches intended for low voltage (600 V and less) distribution systems. Simple theoretical analysis enables the calculation of the optimal switching times to minimize transients. These calculations take into account the system impedance and the initial capacitor voltages.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Peresters. IV. Substituent Effects upon the Concerted Decomposition of t-Butyl Phenylperacetates<sup>1</sup> (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPeresters. IV. Substituent Effects upon the Concerted Decomposition of t-Butyl Phenylperacetates1Paul D. Bartlett and Christoph RüchardtCite this: J. Am. Chem. Soc. 1960, 82, 7, 1756–1762Publication Date (Print):April 1, 1960Publication History Published online1 May 2002Published inissue 1 April 1960https://pubs.acs.org/doi/10.1021/ja01492a054https://doi.org/10.1021/ja01492a054research-articleACS PublicationsRequest reuse permissionsArticle Views176Altmetric-Citations100LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Hypersensitivity reaction to cancer chemotherapy. (1982)

H YPERSENSITIVITY reactions secondary to cancer chemotherapeutic agents received little attention until publication of a review’ enumerating available information on this subject about the agents in wide clinical use. This article will update that review and explore more deeply the mechanisms for some of these reactions. The term “hypersensitivity reaction” will be used generically to describe any drug related episode with signs and symptoms of any of the four major types of drug induced allergy. It does not imply that all such reactions are mediated immunologically by antibody or sensitized lymphocytes. Although most reactions from cytotoxic agents are immunologically mediated, there are other possible mechanisms for type I or immediate reactions. Some chemotherapeutic agents appear to directly degranulate mast cells and basophils, thus releasing histamine and other vasoactive substances. This direct degranulation phenomenon also occurs from meperidine, morphine, codeine, curare, hydralazine, and radiopaque dyes. Some agents may stimulate the alternative complement activation pathway, resulting in release of vasoactive substances from mast cells. Angioedema and urticaria occasionally result from stressful situations and thus a neural mechanism for vasoaclive mediator release exists. It is not known whether any such instances have occurred in conjunction with cytotoxic drug administration. In the case of bleomytin, acute reactions appear to result from direct pyrogen release from leucocytes, and no immunologic mediators are involved. Hypersensitivity reactions are generally divided into four types originally defined by Gel1 and Coombs.’ Table 1 lists these types and summarizes the mechanisms by which they are produced.
Integrating semantics-based access mechanisms with P2P file systems (2004)

We present an architecture for a peer-to-peer (P2P) file system which supports semantics-based access. Central to this work is to provide semantic indexing and retrieval capabilities. Our semantic indexing and locating approach is based on distributed hash tables (DHTs) where the indices of semantically close files are clustered to the same peers with high probability (nearly 100%) by the use of locality sensitive hash functions. A query for finding semantically close files can be answered by consulting only a small number of peer nodes which are most responsible for such a query, instead of by query flooding. Our approach only adds index information to peer nodes, thus imposing only a small storage overhead. We constitute an initial step to integrate semantics-based access mechanisms into a P2P file system.
Orthogonal Processing: A Novel Photolithographic Patterning Method for Organic Electronics (2009)

Organic electronics is an extensively studied subject opening new horizons in electronics technology. It has attracted great attention as a technology to enable flexible electronic devices through solution processing of organic and polymeric materials. However, patterning of organic materials to construct device components still remains one of the major hurdles to be overcome due to problems with chemical processing. Fundamentally this challenge originates from the limited number of options regarding orthogonal solvents. Recently, we have identified supercritical carbon dioxide (scCO2) and segregated hydrofluoroethers (HFEs) as universal, non-damaging solvents for most non-fluorinated polymeric materials. These unconventional solvents expand processing options from the two-dimensional plane to three-dimensional space by drawing another orthogonal axis. Taking advantage of those noble solvents and fluorinated photoresists, we were able to make patterns of functional organic materials photolithographically. Furthermore, our orthogonal processing method has been applied to the fabrication of a patterned polymer light-emitting device in scCO2 and an organic thin-film transisotor in HFEs.
Diamond Electrodes (1998)

Abstract With their unique chemical stability and high electron mobility, boron‐doped thin diamond films are likely to have favorable properties for a number of electrochemical applications. A review of the recent developments in this field is presented with critical evaluation of the experimental data. In particular, the relationship between the material's characteristics and the electrochemical behavior of the electrodes is discussed in detail. A number of potential applications for these electrodes are presented: for dimensionally stable electrodes in highly corrosive environments, for discharging toxic effluents, and for electrochemical sensors.
1992 Alfred Bader Award Lecture Probing the specificity of synthetically useful enzymes (1993)

Factors involved in controlling and predicting the structural specificity and stereospecificity of synthetically useful enzymes, including pig liver esterase, subtilisin BPN′ and Carlsberg, α-chymotrypsin, and an L-lactate dehydrogenase, are discussed.
Metallothionein‐I+II in neuroprotection (2009)

Metallothionein (MT)-I+II synthesis is induced in the central nervous system (CNS) in response to practically any pathogen or disorder, where it is increased mainly in reactive glia. MT-I+II are involved in host defence reactions and neuroprotection during neuropathological conditions, in which MT-I+II decrease inflammation and secondary tissue damage (oxidative stress, neurodegeneration, and apoptosis) and promote post-injury repair and regeneration (angiogenesis, neurogenesis, neuronal sprouting and tissue remodelling). Intracellularly the molecular MT-I+II actions involve metal ion control and scavenging of reactive oxygen species (ROS) leading to cellular redox control. By regulating metal ions, MT-I+II can control metal-containing transcription factors, zinc-finger proteins and p53. However, the neuroprotective functions of MT-I+II also involve an extracellular component. MT-I+II protects the neurons by signal transduction through the low-density lipoprotein family of receptors on the cell surface involving lipoprotein receptor-1 (LRP1) and megalin (LRP2). In this review we discuss the newest data on cerebral MT-I+II functions following brain injury and experimental autoimmune encephalomyelitis.
Spatially isothermal graphite furnace for atomic absorption spectrometry using side-heated cuvettes with integrated contacts (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpatially isothermal graphite furnace for atomic absorption spectrometry using side-heated cuvettes with integrated contactsWolfgang. Frech, Douglas C. Baxter, and Bruno. HuetschCite this: Anal. Chem. 1986, 58, 9, 1973–1977Publication Date (Print):August 1, 1986Publication History Published online1 May 2002Published inissue 1 August 1986https://pubs.acs.org/doi/10.1021/ac00122a013https://doi.org/10.1021/ac00122a013research-articleACS PublicationsRequest reuse permissionsArticle Views91Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Low Complexity Codebook-Based Beamforming for MIMO-OFDM Systems in Millimeter-Wave WPAN (2011)

In this paper, we consider a beamforming system in millimeter-wave wireless personal area networks (WPAN), where transmit and receive weight vectors are jointly derived by exchanging a training sequence repeatedly with different combinations of transmit and receive weight vectors. We propose a low complexity codebook-based beamforming scheme that consists of multiple levels and level-adaptive antenna selection in order to reduce the beamforming setup time. For each level, 1) the transmit and receive antennas are selected according to pre-determined inter-element spacings, 2) the training sequences are sent with different weight vectors from a pre-defined codebook and 3) the receiver selects the best transmit and receive weight vectors in order to optimize an effective signal-to-noise ratio (SNR) and these vectors are used to determine the codebook for the next following level. Even with low complexity, we show from the numerical results that our proposed scheme can provide an effective SNR gain and an average spectral efficiency approaching those of the codebook-based beamforming with exhaustive search.
Medstract (2002)

The automatic extraction of information from Medline articles and abstracts (commonly referred to now as the biobibliome) promises to play an increasingly critical role in aiding research while speeding up the discovery process. We have been developing robust natural language tools for the automated extraction of structured information from biomedical texts as part of a project we call MEDSTRACT. Here we will describe an architecture for developing databases for domain specific information servers for research and support in the biomedical community. These are currently comprised of the following: a Bio-Relation Server, and the Bio-Acronym server, Acromed, which will include also aliases. Each information server is derived automatically from an integration of diverse components which employ robust natural language processing of Medline text and IE techniques. The front-end consists of conventional search and navigation capabilities, as well as visualization tools that help to navigate the databases and explore the results of a search. It is hoped that this set of applications will allow for quick, structured access to relevant information on individual genes by biologists over the web.
Enriching SenticNet Polarity Scores through Semi-Supervised Fuzzy Clustering (2012)

SenticNet 1.0 is one of the most widely used freely-available resources for concept-level opinion mining, containing about 5,700 common sense concepts and their corresponding polarity scores. Specific affective information associated to such concepts, however, is often desirable for tasks such as emotion recognition. In this work, we propose a method for assigning emotion labels to SenticNet concepts based on a semi-supervised classifier trained on WordNet-Affect emotion lists with features extracted from various lexical resources.
A quality control algorithm for DNA sequencing projects (1993)

Heterologous DNA sequences from rearrangements with the genomes of host cells, genomic fragments from hybrid cells, or impure tissue sources can threaten the purity of libraries that are derived from RNA or DNA. Hybridization methods can only detect contaminants from known or suspected heterologous sources, and whole library screening is technically very difficult. Detection of contaminating heterologous clones by sequence alignment is only possible when related sequences are present in a known database. We have developed a statistical test to identify heterologous sequences that is based on the differences in hexamer composition of DNA from different organisms. This test does not require that sequences similar to potential heterologous contaminants are present in the database, and can in principle detect contamination by previously unknown organisms. We have applied this test to the major public expressed sequence tag (EST) data sets to evaluate its utility as a quality control measure and a peer evaluation tool. There is detectable heterogeneity in most human and C.elegans EST data sets but it is not apparently associated with cross-species contamination. However, there is direct evidence for both yeast and bacterial sequence contamination in some public database sequences annotated as human. Results obtained with the hexamer test have been confirmed with similarity searches using sequences from the relevant data sets.
Fast and High Precision Positioning Control of High-Speed Motors (2014)

This article presents a double interrupt and frequency-doubled angle compensation control method based on the minimum inductance characteristic of high-speed motor. Moreover, this article designs a proportional-integral-integral-proportional (PI-IP) control structure to realise that the control system can track the d-axis current step response within 330 mus based on the high response characteristic design requirements of the high-speed motor. The effectiveness of this method has been verified by simulations and experiments. The proposed controller has a better ability to track the speed instruction in the case of mutations of the external load. It also has an excellent robustness to respond to the speed when the rotational inertia is changed. The authors design a system to test a high-speed motor whose rated power is 100 W and rated speed is 17,000 rpm. The results show that the method above can realise the high response and high precision servo control of high-speed motor without delay effectively.
An Extensible Framework for Improving a Distributed Software System's Deployment Architecture (2011)

A distributed system's allocation of software components to hardware nodes (i.e., deployment architecture) can have a significant impact on its quality of service (QoS). For a given system, there may be many deployment architectures that provide the same functionality, but with different levels of QoS. The parameters that influence the quality of a system's deployment architecture are often not known before the system's initial deployment and may change at runtime. This means that redeployment of the software system may be necessary to improve the system's QoS properties. This paper presents and evaluates a framework aimed at finding the most appropriate deployment architecture for a distributed software system with respect to multiple, possibly conflicting QoS dimensions. The framework supports formal modeling of the problem and provides a set of tailorable algorithms for improving a system's deployment. We have realized the framework on top of a visual deployment architecture modeling and analysis environment. The framework has been evaluated for precision and execution-time complexity on a large number of simulated distributed system scenarios, as well as in the context of two third-party families of distributed applications.
The Role of Glutamine 114 in Old Yellow Enzyme (2002)

Glutamine 114 of OYE1 is a well conserved residue in the active site of the Old Yellow Enzyme family. It forms hydrogen bonds to the O2 and N3 of the flavoprotein prosthetic group, FMN. Glutamine 114 was mutated to asparagine, introducing an R-group that is one methylene group shorter. The resultant enzyme was characterized to determine the effect of the mutation on the mechanistic behavior of the enzyme, and the crystal structure was solved to determine the effect of the mutation on the structure of the protein. The Q114N mutation results in little change in the protein structure, moving the amide group of residue 114 out of H-bonding distance, allowing repositioning of the FMN prosthetic group to form new interactions that replace the lost H-bonds. The mutation decreases the ability to bind ligands, as all dissociation constants for substituted phenols are larger than for the wild type enzyme. The rate constant for the reductive half-reaction with beta-NADPH is slightly greater, whereas that for the oxidative half-reaction with 2-cyclohexenone is smaller than for the wild type enzyme. Oxidation with molecular oxygen is biphasic and involves formation and reaction with O(2), a phenomenon that is more pronounced with this mutation than with wild type enzyme. When superoxide dismutase is added to the reaction, we observe a single-phase reaction typical of the wild type enzyme. Turnover reactions using beta-NADPH with 2-cyclohexenone and molecular oxygen were studied to further characterize the mutant enzyme.
Low Power and Scalable Many-Core Architecture for Big-Data Stream Computing (2014)

In the last years the process of examining large amounts of different types of data, or Big-Data, in an effort to uncover hidden patterns or unknown correlations has become a major need in our society. In this context, stream mining applications are now widely used in several domains such as financial analysis, video annotation, surveillance, medical services, traffic prediction, etc. In order to cope with the Big-Data stream input and its high variability, modern stream mining applications implement systems with heterogeneous classifiers and adapt online to its input data stream characteristics variation. Moreover, unlike existing architectures for video processing and compression applications, where the processing units are reconfigurable in terms of parameters and possibly even functions as the input data is changing, in Big-Data stream mining applications the complete computing pipeline is changing, as entirely new classifiers and processing functions are invoked depending on the input stream. As a result, new approaches of reconfigurable hardware platform architectures are needed to handle Big-Data streams. However, hardware solutions that have been proposed so far for stream mining applications either target high performance computing without any power consideration (i.e., limiting their applicability in small-scale computing infrastructures or current embedded systems), or they are simply dedicated to a specific learning algorithm (i.e., limited to run with a single type of classifiers). Therefore, in this paper we propose a novel low-power many-core architecture for stream mining applications that is able to cope with the dynamic data-driven nature of stream mining applications while consuming limited power. Our exploration indicates that this new proposed architecture is able to adapt to different classifiers complexities thanks to its multiple scalable vector processing units and their re-configurability feature at run-time. Moreover, our platform architecture includes a memory hierarchy optimized for Big-Data streaming and implements modern fine-grained power management techniques over all the different types of cores allowing then minimum energy consumption for each type of executed classifier.
Structure-Inhibitory Activity Relationship of Plasmin and Plasma Kallikrein Inhibitors. (2001)

Based on the structure of Tra-Tyr(O-Pic)-octylamide, a portion of the octylamine was replaced with moieties bearing hydrophobic, basic or acidic groups. Replacement of the C-terminal residue with a moiety bearing a hydrophobic group gave the proper affinity of the inhibitor to both plasmin (PL) and plasma kallikrein (PK). While addition of a basic residue did not improve the affinity of the inhibitor, a carboxylic acid attached to the phenyl ring increased the PK selectivity of the inhibitor.
Angiotensin-Converting Enzyme Inhibitor Therapy and Colorectal Cancer Risk (2014)

Long-term/high dose exposure to ACE-Is/ARBs may be associated with a decreased incidence of CRC.