gebhart/patrepeval huggingface dataset:
Mixed infestation of sarcoptic and chorioptic mange mites in Japanese serow, Capricornis crispus Temminck, 1845 in Japan, with a description of Chorioptes japonensis sp. nov. (Acari : Psoroptidia) (2001)

Seven Japanese serows, Capricornis crispus, with clinical signs of mange were used for parasitological and histopathological examinations. Five of the seven animals examined were positive only for Chorioptes mites. On the other two animals, however, a mixed infestation with Sarcoptes scabiei and Chorioptes mites was observed. This Chorioptes mite was proposed as a new species, Chorioptes japonensis Takahashi et Nogami, sp. nov. Histopathologically, parakeratotic and hyperkeratotic crusts were observed in the epidermis, and many cross-sections of S. scabiei mites were also found in the focal thickened stratum corneum. Chorioptes mites were observed on all Japanese serows examined from 1975 to 1997. However, S. scabiei were only observed on the two animals examined in 1996 and 1997. Before then, S. scabiei were not observed.
Sparser, Better, Faster GPU Parsing (2014)

Due to their origin in computer graphics, graphics processing units (GPUs) are highly optimized for dense problems, where the exact same operation is applied repeatedly to all data points. Natural language processing algorithms, on the other hand, are traditionally constructed in ways that exploit structural sparsity. Recently, Canny et al. ( In this work, we reintroduce sparsity to GPU parsing by adapting a coarse-to-fine pruning approach to the constraints of a GPU. The resulting system is capable of computing over 404 Viterbi parses per second-more than a 2x speedup-on the same hardware. Moreover, our approach allows us to efficiently implement less GPU-friendly minimum Bayes risk inference, improving throughput for this more accurate algorithm from only 32 sentences per second unpruned to over 190 sentences per second using pruning-nearly a 6x speedup.
Developing a Framework for Measuring Outsourcing Performance (2010)

Purpose: The popularity and growth in outsourcing has resulted in many different outsourcing arrangements, from strategic and business process outsourcing to selective and tactical outsourcing, on a national or global scale. Outsourcing is frequently considered a vital ingredient to corporate restructuring and business improvement initiatives. However, it is often treated as a fixed discreet event such as a make or buy decision. As the rational and strategic implications of outsourcing vary, so too does the required outsourcing process and performance measures. The purpose of this paper is to review and synthesis available empirical literature on outsourcing frameworks and performance management techniques, and develop a framework for measuring outsourcing performance. Research Approach: A sample of empirical academic publications on outsourcing frameworks and performance measures, across various scholarly journals constitute the main data for analytical purposes. It is compiled from searches of the main academic databases. The studies in the sample are clustered according to their main research areas, with a narrative approach being used to review developments in each area. Following analysis of the reviewed literature, a number of the frameworks and their measures are adapted and integrated to develop a conceptual framework for measuring outsourcing performance. Findings and Originality: This conceptual based framework brings an integrated perspective to outsourcing. It develops a dynamic process of strategic alignment between environmental drivers, corporate outsourcing objectives, the outsourcing process and the performance measures. The proposed conceptual framework seeks to integrate the environmental and organisational outsourcing drivers down into the outsourcing process, culminating in a managed outsourcing relationship. Research Impact: For both the researcher and practioner, the measured outsourcing framework will provide a more holistic approach when considering and implementing outsourcing. Practical Impact: This paper is a first step towards developing a framework for measuring outsourcing performance, which practioners will be able to apply when considering, analysing and managing an outsourcing initiative.
Production of<scp>l</scp>-Threonine by Analog-resistant Mutants (1972)

Mutants resistant to α-amino-β-hydroxyvaleri0c acid (AHV) were derived from various bacteria which belong to Corynebacterium, Brevibacterium, Arthrobacter, Microbacterium, or Bacillus by mutational treatment with N-methyl-N′-nitro-N-nitrosoguanidine(NTG), and screened for their ability to produce l-threonine. A number of l-threonine producers were obtained from each group of bacteria. Among them, the mutants derived from C. glutamicum KY9159(Met−) were further mutagenized with NTG to derive thialysine(S-Lys)-resistant mutants. An AHV-resistant mutant, KY10484 was proved to be much more sensitive to the growth inhibition by thialysine than the parent strain, KY9159. From KY10484, a number of AHV- and thialysine-resistant mutants were derived. Approximately a half of these mutants were found to produce more l-threonine than KY10484. Among these mutants, KY10440 (Met−, AHVR, s-LysR) was used to investigate the cultural conditions for l-threonine production. The growth of KY10440 decreased largely with addition of l-homoserine, a threonine precursor. l-Asparagine, l-cystine, l-glutamine or l-arginine partially reversed the inhibitory effect of l-homoserine. Addition of these amino acids at low level led to increase l-threonine production. The amount of l-threonine accumulation reached to a level of 14mg/ml with a medium containing 10% glucose and to a level of 10 mg/ml with a medium containing 5% molasses (as glucose). Another AHV- and thialysine-resistant mutant, KY10251 which was also derived from KY9159 was found to produce both 9 mg/ml of l-threonine and 5.5 mg/ml of l-lysine in a culture broth.
The Potential of Pentagonal Building Blocks: From Giant Ring‐Shaped to Spherical Polyoxometalate Clusters (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
The mitochondrial effects of novel apoptogenic molecules generated by psoralen photolysis as a crucial mechanism in PUVA therapy (2007)

The generation of photoproducts of psoralen (POPs) might be relevant in cell death induced by psoralen plus UVA, namely PUVA, which is a recognized effective treatment for cutaneous T-cell lymphoma, chronic graft-versus-host disease, and psoriasis. We investigated the occurrence of POP-induced cell death and the underlying mechanisms. POPs were produced by irradiating a psoralen solution with UVA. Jurkat cells treated in the dark with these mixtures died mainly through an apoptotic mechanism. POPs were separated by high-performance liquid chromatography (HPLC), and cells were added with each of these fractions. A total of 2 dimers of psoralen and 6-formyl-7-hydroxycoumarin (FHC) were identified in the apoptogenic fractions. Apoptosis was preceded by mitochondrial dysfunction caused by the opening of the mitochondrial permeability transition pore (PTP). In fact, both mitochondrial depolarization and cell death were prevented by the PTP inhibitor cyclosporin A (CsA). PTP opening was also documented in isolated mitochondria added with POP, suggesting that apoptosis is caused by a direct effect of POP on mitochondria. In fact, FHC alone induced PTP opening and CsA-inhibitable cell death of Jurkat cells, whereas nontransformed T lymphocytes were resistant. Along with identifying novel apoptogenic molecules, the present results indicate that POP generation directs transformed cells to apoptosis.
Identification of polyurethanes by high resolution nuclear magnetic resonance spectrometry (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of polyurethanes by high resolution nuclear magnetic resonance spectrometryEdward G. Brame, Raymond C. Ferguson, and George J. ThomasCite this: Anal. Chem. 1967, 39, 4, 517–521Publication Date (Print):April 1, 1967Publication History Published online1 May 2002Published inissue 1 April 1967https://pubs.acs.org/doi/10.1021/ac60248a004https://doi.org/10.1021/ac60248a004research-articleACS PublicationsRequest reuse permissionsArticle Views445Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Changes in the Tangent Modulus of Rabbit Septal and Auricular Cartilage Following Electromechanical Reshaping (2011)

Transforming decades' old methodology, electromechanical reshaping (EMR) may someday replace traditionally destructive surgical techniques with a less invasive means of cartilage reshaping for reconstructive and esthetic facial surgery. Electromechanical reshaping is essentially accomplished through the application of voltage to a mechanically deformed cartilage specimen. While the capacity of the method for effective reshaping has been consistently shown, its associated effects on cartilage mechanical properties are not fully comprehended. To begin to explore the mechanical effect of EMR on cartilage, the tangent moduli of EMR-treated rabbit septal and auricular cartilage were calculated and compared to matched control values. Between the two main EMR parameters, voltage and application time, the former was varied from 2-8 V and the latter held constant at 2 min for septal cartilage, 3 min for auricular cartilage. Flat platinum electrodes were used to apply voltage, maintaining the flatness of the specimens for more precise mechanical testing through a uniaxial tension test of constant strain rate 0.01 mm/s. Above 2 V, both septal and auricular cartilage demonstrated a slight reduction in stiffness, quantified by the tangent modulus. A thermal effect was observed above 5 V, a newly identified EMR application threshold to avoid the dangers associated with thermoforming cartilage. Optimizing EMR application parameters and understanding various side effects bridge the gap between EMR laboratory research and clinical use, and the knowledge acquired through this mechanical study may be one additional support for that bridge.
Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues (2017)

Immune-profiling is becoming an important tool to identify predictive markers for the response to immunotherapy. Our goal was to validate multiplex immunofluorescence (mIF) panels to apply to formalin-fixed and paraffin-embedded tissues using a set of immune marker antibodies, with the Opal™ 7 color Kit (PerkinElmer) in the same tissue section. We validated and we described two panels aiming to characterize the expression of PD-L1, PD-1, and subsets of tumor associated immune cells. Panel 1 included pancytokeratin (AE1/AE3), PD-L1, CD4, CD8, CD3, CD68, and DAPI, and Panel 2 included pancytokeratin, PD-1, CD45RO, granzyme B, CD57, FOXP3, and DAPI. After all primary antibodies were tested in positive and negative controls by immunohistochemistry and uniplex IF, panels were developed and simultaneous marker expressions were quantified using the Vectra 3.0™ multispectral microscopy and image analysis InForm™ 2.2.1 software (PerkinElmer).These two mIF panels demonstrated specific co-localization in different cells that can identify the expression of PD-L1 in malignant cells and macrophages, and different T-cell subpopulations. This mIF methodology can be an invaluable tool for tumor tissue immune-profiling to allow multiple targets in the same tissue section and we provide that is accurate and reproducible method when is performed carefully under pathologist supervision.
Method of Estimating Human Orientation Using Array Antenna (2018)

This paper presents a method that uses microwaves to estimate human body orientation. The antennas are arranged to surround the human and observe vital signs such as respiration and heart beat from the microwaves reflected from the human. Since the signal reflected from the front of the human will fluctuate the most, mainly due to respiration, human body orientation is estimated by finding the antenna that captures the largest rhythmic fluctuation. In experiments with three subjects, the median value of angular error of human orientation was 9.01∼23.35°.
F<sub>420</sub>H<sub>2</sub>:NADP oxidoreductase from <i>Methanobacterium thermoautotrophicum</i>: identification of the encoding gene via functional overexpression in <i>Escherichia coli</i> (1998)

F420H2:NADP oxidoreductase is found in methanogenic, sulfate-reducing and halophilic archaea and also in some bacteria. The putative gene encoding the enzyme was cloned from Methanobacterium thermoautotrophicum (strain Marburg) and heterologously expressed in Escherichia coli. The overproduced active enzyme was purified, characterized and crystallized.
A Comparison of Measuring Methods for Particle Size Distribution (1988)

To improve reliability of measurements of particle size distribution, performances and characteristics of three measuring methods, scanning electron microscope-image analysis (SEM-IA), electric resistance analysis (ERA) and centrifugal sedimentation analysis (CSA), are compared and discussed. In this study, polystyrene/polyviniltoluene (PS/PVT), monodisperse particles and alumina particles ranging from 0.5 to 5μm in diameter are used.It is shown that the ERA's data on the particle size distribution agrees with the SEM-IA's within 5% in the average diameter and within 0.05μm in the standard deviation for the PS/PVT monodisperse particles, but the CSA's data significantly differ from those of the others. In the CSA, Stokes' condition for particle sedimentation is distinctly disturbed by a temperature rise due to high speed rotation of sample. A new technique is proposed and confirmed to be effective to reduce the disturbance.In the measurement of alumina particles, the obtained data are incompatible each other among the three measuring methods, because amorphous particle shape and wide size distribution of alumina particles give inherent and different characteristics for the particle detections in the respective measuring methods.
Identification of Bitter Off-Taste Compounds in the Stored Cold Pressed Linseed Oil (2007)

Whereas freshly pressed linseed oil provides a delicate nutty flavor, a lingering bitter off-taste is developing upon storage at room temperature. Using a sensory guided fractionation approach, the key bitter compound was identified in stored linseed oil, and its structure was determined as the methionine sulfoxide-containing, cyclic octapeptide cyclo(PLFIM OLVF) by means of FTIR, LC-MS, NMR spectroscopy, and amino acid analysis. Although this peptide is known in the literature as cyclolinopeptide E, the bitter taste activity of this compound has not previously been described. Sensory evaluation revealed a recognition threshold concentration of 12.3 micromol/L water.
A simple shallow water propagation model including shear wave effects (1985)

The Pekeris model has proved to be very useful in describing some features of acoustic propagation in shallow water, and as a simple test of ideas in normal mode theory. The basic model consists of a homogeneous layer of fluid overlying an infinite homogeneous fluid half-space of greater sound speed. Here, we extend the Pekeris model to handle the case of a fluid overlying an elastic basement in which the shear speed is less than the (compressional) speed of sound in the fluid. This gives rise to leaky modes in which both the mode eigenfunctions and eigenvalues are complex. The model predictions are compared to some measured propagation losses for a shallow water site overlying a chalk bottom, where compressional to shear wave conversion at the water–chalk interface causes large losses. The predictions of the simple model explain the very high losses measured at frequencies less than 200 Hz. At higher frequencies the sound-speed profile, absorption of sound by the water, and the effects of a thin sediment layer become important, but then an all-fluid normal mode model is in agreement with the measured results.
Terminal mode (2010)

Mobile devices such as smart phones have enabled consumers to gain access to a growing number of interactive and useful applications, anytime anywhere. However, once a user enters his/her vehicle the availability of such applications and their user experience degrades drastically -- either because of being restricted to using the few applications available on the In-Vehicle Infotainment (IVI) system or due to the challenges of interacting with a tiny mobile device screen attached to a car dock. In this paper, we present Terminal Mode -- a technology which transforms mobile devices into automotive application platforms and seamlessly integrates them into vehicle infotainment systems. This technology not only enables consumers to access their favorite mobile services and applications in a safe manner while traveling in a vehicle but also provides top quality user experience consistent with high-end IVI systems.
The management of coronavirus infections with particular reference to SARS (2008)

The human coronaviruses (HCoV) OC43 and 229E are common causes of upper respiratory tract infections. Severe diseases were rare, however, until the emergence of the severe acute respiratory syndrome (SARS)-CoV in 2003. Since then, other novel CoV (NL63 and HKU1) have been described, and they have caused respiratory infections worldwide. Potentially exposed laboratory workers or animal handlers with rapidly progressive pneumonia not responding to standard antibacterial coverage must be isolated with contact and droplet, and for specific situations, airborne precautions, till rapid tests of respiratory and faecal samples are negative for SARS-CoV. Generally, the viral loads collected at different anatomical sites correlate with the severity of symptoms and mortality. Shedding of SARS-CoV peaks at day 10 after the onset of symptoms, which theoretically allows ample time for antiviral treatment. The disease is characterized by uncontrolled replication of the virus and a prominent pro-inflammatory response. No randomized controlled trials with a specific anti-coronavirus agent have been conducted with respect to therapy or prophylaxis. Reports using historical matched controls have suggested that treatment with interferon alfacon-1 (a synthetic interferon) combined with steroid, protease inhibitors together with ribavirin, or convalescent plasma containing neutralizing antibody, could be useful. Prophylaxis with interferon or hyperimmune globulin may be considered for unprotected exposure. The role of immunomodulators to decrease excessive inflammation remains elusive. Other non-SARS-CoV infections are generally milder in immunocompetent hosts, and scientific data on antiviral treatment of these viruses are scarce.
Input impedance of a coaxial line probe feeding a circular waveguide in the TM/sub 01/ mode (1990)

By means of the conversion of complex power technique (CCPT), a formally exact full-wave solution is given for the case of a coaxial line probe fending a circular waveguide for TM/sub 01/ modal excitation. The overall scattering matrix of the coaxial-line-prove-circular-waveguide system is deduced. Numerical results for the impedance as 'seen' by the coaxial line are presented and compared with experimental results obtained in the 9.0-11.5-GHz frequency range. Their agreement is reasonably good except at the lower frequencies (<10.0 GHz), where the TM/sub 01/ mode in the circular guide is close to its cutoff frequency (8.14 GHz).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Functionalized chitosan electrospun nanofiber for effective removal of trace arsenate from water (2016)

An environment-friendly iron functionalized chitosan elctrospun nanofiber (ICS-ENF) was synthesized for trace arsenate removal from water. The ICS-ENF was fabricated by electrospinning a mixture of chitosan, PEO and Fe(3+) followed by crosslinking with ammonia vapor. The physicochemical properties of ICS-ENF were characterized by FESEM, TEM-EDX and XRD. The ICS-ENF was found to be highly effective for As(V) adsorption at neutral pH. The As(V) adsorption occurred rapidly and achieved equilibrium within 100 min, which was well fitted by pseudo-second-order kinetics model. The As(V) adsorption decreased with increased ionic strength, suggesting an outer-sphere complexation of As(V) on ICS-ENF. Freundlich model well described the adsorption isotherm, and the maximum adsorption capacity was up to 11.2 mg/g at pH 7.2. Coexisting anions of chloride and sulfate showed negligible influence on As(V) removal, but phosphate and silicate significantly reduced As(V) adsorption by competing for adsorption sites. FTIR and XPS analysis demonstrated -NH, -OH and C-O were responsible for As(V) uptake. ICS-ENF was easily regenerated using 0.003 M NaOH, and the removal rate remained above 98% after ten successively adsorption-desorption recycles. This study extends the potential applicability of electrospun nanofibers for water purification and provides a promising approach for As(V) removal from water.
Transport Systems for <scp>l</scp> -Methionine in <i>Escherichia coli</i> (1974)

The transport of l-methionine into cells of Escherichia coli is described. The transported methionine undergoes a fairly rapid conversion to other cellular metabolites, primarily polyamines, but within 2 min, at least 65% of the intracellular label remains as methionine. The uptake process, which is temperature dependent, allows the accumulation of methionine against a concentration gradient. The dependence of the initial rate of uptake on the extracellular substrate concentration indicates the presence of multiple transport systems, whose kinetic behavior can be approximated by two systems, one with K(T) = 7.5 x 10(-8) M and V(T) = 200 pmol per muliter of cell water per min, and the other with K(T) = 40 x 10(-6) M and V(T) = 1,550 pmol per muliter per min. Both systems are highly specific for l-methionine. Methionine derivatives substituted on the amino or carboxyl group were somewhat effective as inhibitors of l-methionine uptake, whereas d-methionine, ethionine, or other amino acids were poorly inhibitory, if at all. The uptake process is dependent on metabolic energy, but apparently this energy can be derived either from glycolysis or from oxidative phosphorylation. Efflux of methionine was demonstrable, and both the influx and efflux process were susceptible to inhibition by N-ethylmaleimide. The intracellular pool of l-methionine was estimated to be 0.1 to 0.3 mM. The transport in two mutant strains defective in methionine uptake (metD and metP) showed that the high-affinity transport system was lost, whereas the low-affinity system remained more or less intact.
Enabling 18nm-particle detection on Si surfaces by conventional laser scattering (2010)

According to ITRS2009, the detection of 18nm particles is required for 2010, but the latest laser scattering wafer inspection system is not capable of detecting particles smaller than 28 nm. Therefore, it is necessary to establish the method of detecting smaller particles.