gebhart/patrepeval huggingface dataset:
Experiments in curvature-based segmentation of range data (1995)

This paper focuses on the experimental evaluation of a range image segmentation system which partitions range data into homogeneous surface patches using estimates of the sign of the mean and Gaussian curvatures. The authors report the results of an extensive testing program aimed at investigating the behavior of important experimental parameters such as the probability of correct classification and the accuracy of curvature estimates, measured over variations of significant segmentation variables. Evaluation methods in computer vision are often unstructured and subjective: this paper contributes a useful example of extensive experimental assessment of surface-based range segmentation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
[Complications of the deep infections of the neck]. (2006)

Deep infections of the neck are potentially life-threatening for their descending spread along cervical fascia planes towards the mediastinum and development of sepsis after thrombophlebitis of the internal jugular vein. The aim of the present report is to review the complications of the deep neck infections and their surgical treatment for the period of the last 5 years. From 1999 to 2003 29 patients with deep cervical infections were treated surgically. Twelve of the patients had submandibular abscess, 10 cases were with parapharyngeal abscess, 3 with Ludwig's angina, 1 with mastoiditis with exteriorization in the neck and 3 with neck phlegmonas. The infections were most frequently of tonsillar and dental origin. The following complications were observed: 6 cases with acute obstruction of the upper airways treated with tracheostomy; 2 cases with sepsis; 2 with descending mediastinitis; and 1 with acute hemorrhage of stress ulcer of the stomach treated with laparotomy and laparostomy. Combined surgical and massive antibiotic treatment according to the bacteriological findings was carried out. Cervical incisions, jugulotomy and thoracotomy were performed in cases with descending mrdiastinitis. Permanent suction drainage and lavage of the abscess cavities were used. In cervical phlegmonas the surgical wounds were left open against anaerobic infection. Three cases of deep cervical infections, complicated with mediastinitis, sepsis, VII and XI cranial nerves paresis, hemorrhages from the gastrointestinal tract are cited. The third case is interesting with the multiple complications of the deep neck infection--stress ulcer of the stomach, which could not be managed endoscopically because of the compression due to hypopharingeal edema, sepsis, tracheal stenosis. All the patients but one recovered after the treatment. One of them with cervical phlegmona died out of heart arrest in the operating theater after urgent intubation and tracheotomy for airway obstruction. The great importance of the early surgical treatment of neck infections, the use of antibiotics covering both aerobic and anaerobic bacterial spectrum and the good coordination between otolaryngologists, surgeons, reanimators and microbiologists is stressed in conclusion.
Quantitative Structural Analysis of Peripheral Airways and Arteries in Sudden Fatal Asthma (1991)

The peripheral airways and the adjacent muscular pulmonary arteries were studied by morphometric methods in the autopsy lungs of six asthmatic subjects who died suddenly during an asthma attack, and they were compared with those of six control subjects who died of other causes and had no history of respiratory diseases. Bronchioles of asthmatic subjects had an increased amount of lumen occlusion (p less than 0.01), smooth muscle thickness (p less than 0.001), and inflammatory infiltrate (p less than 0.001), and both mononuclear cells and eosinophils contributed to this increased inflammation. The muscular pulmonary arteries adjacent to occluded and inflamed bronchioles did not have the morphologic features of chronic hypoxia, as shown by the normal medial and intimal thickness, but they had an important inflammatory process in their walls that was particularly marked at sites adjacent to airways. Although the functional significance of these findings is unknown, they may be responsible in part for the gas exchange abnormalities observed in acute severe asthma.
Low temperature growth of ZnS<i>x</i>Se1−<i>x</i> alloys fabricated by hydrogen radical enhanced chemical vapor deposition in an atomic layer epitaxy mode (1993)

We have grown ZnSxSe1−x alloys on a GaAs(100) substrate in a wide compositional range (0≤ x≤0.3) by the insertion of the ZnS monolayer into the ZnSe multilayers. We have succeeded in growing these alloys at temperatures as low as 200 °C using the hydrogen radical enhanced chemical vapor deposition (HRCVD) in the atomic layer epitaxy (ALE) mode. In the ALE-HRCVD, it is the self-limiting action, realized on both surfaces covered with Se and Zn, which leads to the high-quality crystals. In the photoluminescence spectra of these ZnSxSe1−x alloys we have observed only the sharp emission lines at the band edges (2.80–2.90 eV) which we attribute predominantly to the excitons. The structural fluctuations have been remarkably reduced by the layer-by-layer method. In addition, we have found very low defect density in these crystals despite the large lattice deformation due to the lattice mismatch. An ordered alloy [(ZnS)2(ZnSe)24]69 has been made by the optimization of the growth conditions.
WebRanz: web page randomization for better advertisement delivery and web-bot prevention (2016)

Nowadays, a rapidly increasing number of web users are using Ad-blockers to block online advertisements. Ad-blockers are browser-based software that can block most Ads on the websites, speeding up web browsers and saving bandwidth. Despite these benefits to end users, Ad-blockers could be catastrophic for the economic structure underlying the web, especially considering the rise of Ad-blocking as well as the number of technologies and services that rely exclusively on Ads to compensate their cost. In this paper, we introduce WebRanz that utilizes a randomization mechanism to circumvent Ad-blocking. Using WebRanz, content publishers can constantly mutate the internal HTML elements and element attributes of their web pages, without affecting their visual appearances and functionalities. Randomization invalidates the pre-defined patterns that Ad-blockers use to filter out Ads. Though the design of WebRanz is motivated by evading Ad-blockers, WebRanz also benefits the defense against bot scripts. We evaluate the effectiveness of WebRanz and its overhead using 221 randomly sampled top Alexa web pages and 8 representative bot scripts.
Functional metal‐porphyrazine derivatives and their polymers, 2. Synthesis and properties of polyimides containing metal‐phthalocyanines (1979)

Abstract A novel class of polyimides (14) containing Mt(II)‐phthalocyanine rings has been synthesized by the solution condensation in N ‐methyl‐2‐pyrrolidone (NMP) of Mt(II)‐[2,9or10(or2, 16or17)bis(3,4‐dicarboxybenzoyl)]phthalocyanine dianhydride (Mt(II)‐dahPc; Mt(II)=Co(II), Ni(II) and Cu(II); (2–4) ) with aromatic diamines such as 4,4′‐methylenebis(aniline), followed by thermal imidization in vacuo at 200°C. The polyamides obtained were soluble in NMP and hexamethylphosphoric triamide, having inherent viscosities up to 0,7 dl·g −1 . The polyimides were stable up to 350°C, and showed room temperature‐dc‐resistivities in the range of 10 11 to 10 6 Ω·cm.
A Practical 24 Channel Microelectrode for Neural Recording in Vivo (1981)

We have developed a multichannel microelectrode that has 24 recording sites, spaced at 85 μm intervals along the edge of its tip. The sites are arranged in one of two ways: either as a 1 ×24 linear array along one edge or as a 2 ×12 array along both edges. In the first, the sites span 2 mm while in the second, the sites span 1 mm ×135 μm.
Deoxidation mechanism in low carbon steel killed with aluminium (2001)

status: Published
NMR Relaxation Studies of Solute-Solvent Interactions (1978)

Machine learning (ML) is transforming all areas of science. The complex and time-consuming calculations in molecular simulations are particularly suitable for an ML revolution and have already been profoundly affected by the application of existing ML ...Read More
New Insights into the Assembly of Extracellular Microfibrils from the Analysis of the Fibrillin 1 Mutation in the <i>Tight skin</i> Mouse (2000)

The Tight skin (Tsk) mutation is a duplication of the mouse fibrillin 1 (Fbn1) gene that results in a larger (418 kD) than normal (350 kD) protein; Tsk/+ mice display increased connective tissue, bone overgrowth, and lung emphysema. Lung emphysema, bone overgrowth, and vascular complications are the distinctive traits of mice with reduced Fbn1 gene expression and of Marfan syndrome (MFS) patients with heterozygous fibrillin 1 mutations. Although Tsk/+ mice produce equal amounts of the 418- and 350-kD proteins, they exhibit a relatively mild phenotype without the vascular complications that are associated with MFS patients and fibrillin 1-deficient mice. We have used genetic crosses, cell culture assays and Tsk-specific antibodies to reconcile this discrepancy and gain new insights into microfibril assembly. Mice compound heterozygous for the Tsk mutation and hypomorphic Fbn1 alleles displayed both Tsk and MFS traits. Analyses of immunoreactive fibrillin 1 microfibrils using Tsk- and species-specific antibodies revealed that the mutant cell cultures elaborate a less abundant and morphologically different meshwork than control cells. Cocultures of Tsk/Tsk fibroblasts and human WISH cells that do not assemble fibrillin 1 microfibrils, demonstrated that Tsk fibrillin 1 copolymerizes with wild-type fibrillin 1. Additionally, copolymerization of Tsk fibrillin 1 with wild-type fibrillin 1 rescues the abnormal morphology of the Tsk/Tsk aggregates. Therefore, the studies suggest that bone and lung abnormalities of Tsk/+ mice are due to copolymerization of mutant and wild-type molecules into functionally deficient microfibrils. However, vascular complications are not present in these animals because the level of functional microfibrils does not drop below the critical threshold. Indirect in vitro evidence suggests that a potential mechanism for the dominant negative effects of incorporating Tsk fibrillin 1 into microfibrils is increased proteolytic susceptibility conferred by the duplicated Tsk region.
The Anaesthetic Management of Autistic Children (1998)

Autistic children are difficult to manage and there are no anaesthesia studies to suggest management strategies. We present five case reports which describe an integrated management program taking into account the special needs of autistic children and their families. We describe a method of early warning and recognition of these patients and the establishment of a database to allow review of our program. We also present a process to minimize the stress and problems inherent in the conventional admission process. Oral ketamine (6 to 7 mg/kg) has proven to be the most reliable preoperative sedative for these patients.
Extracellular Vesicles in CNS Developmental Disorders (2020)

The central nervous system (CNS) is the most complex structure in the body, consisting of multiple cell types with distinct morphology and function. Development of the neuronal circuit and its function rely on a continuous crosstalk between neurons and non-neural cells. It has been widely accepted that extracellular vesicles (EVs), mainly exosomes, are effective entities responsible for intercellular CNS communication. They contain membrane and cytoplasmic proteins, lipids, non-coding RNAs, microRNAs and mRNAs. Their cargo modulates gene and protein expression in recipient cells. Several lines of evidence indicate that EVs play a role in modifying signal transduction with subsequent physiological changes in neurogenesis, gliogenesis, synaptogenesis and network circuit formation and activity, as well as synaptic pruning and myelination. Several studies demonstrate that neural and non-neural EVs play an important role in physiological and pathological neurodevelopment. The present review discusses the role of EVs in various neurodevelopmental disorders and the prospects of using EVs as disease biomarkers and therapeutics.
Century of the typewriter (1974)

First edition. A comprehensive history of the world's typewriters. Contains an alphabetical compendium of all known makes of machine, past and present, showing changes of name, dates of production, and manufacturers' names. Signed copy.
Building Customizable Middleware using Aspect-Oriented Programming - Master's Thesis, May 2002 (2002)

In order to support a wide range of applications, Distributed Object Computing (DOC) middleware frameworks such as ACE and TAO have grown to include a vast number of features. For any one application, though, unused functionality either contributes to code bloat, degrades performance or both. When applied to embedded and realtime systems, these issues can preclude the use of middleware altogether. Currently, to address these concerns, middleware developers continually refactor code to relegate functionality to separate libraries. This process is tedious, time-consuming, and adds complexity for both users and developers. To address the difficulties of creating subsettable middleware, we have developed a novel method for constructing middleware using Aspect-Oriented Programming (AOP) and applied it to develop a realtime CORBA Event Channel called the Framework for Aspect Composition of an EvenT channel (FACET). FACET consists of a small, essential core that represents the basic structure and functionality of any event channel. By using aspects, additional features are woven not the core so that the resulting event channel supports all of the features needed by a given embedded application.
Metal artifact reduction based on sinogram correction in CT (2009)

A CT image including metallic objects suffers from strong metal artifacts such as shades and streaks. Most metal artifact reduction algorithms based on filtered back-projection have tried to make a metal-free projection data by modifying the original data on the metal-traces in the sinogram. Although those algorithms are able to reduce metal artifacts, they tend to produce new artifacts and distort non-metallic regions. In this paper, we propose a novel algorithm for reducing metal artifacts while preserving non-metallic region with minimum distortion. In the algorithm, we first generate a metal-free image by removing metallic regions in the initially reconstructed image and interpolating the intensities of metallic regions with those of non-metallic surrounding pixels. Based on the metal-free image, we obtain a reprojection data. We then apply a high-pass filter (HPF) for the reprojection data and interpolate overlapping regions along the metal-trace direction. We merge the processed reprojection data with the low-pass filtered projection data after replacing metal-trace regions with linearly interpolated values. The final reconstructed image is then obtained by using this merged projection data. The proposed algorithm provides much better performance compared with the existing algorithms by effectively reducing shade artifacts between metallic objects without introducing shape distortion of non-metallic objects.
Companion Diagnostics for Targeted Cancer Drugs â€“ Clinical and Regulatory Aspects (2014)

Companion diagnostics (CDx) holds the promise of improving the predictability of the oncology drug development process and become an important tool for the oncologist in relation to the choice of treatment for the individual patient. A number of drug-diagnostic co-development programs have already been completed successfully, and in the clinic, the use of several targeted cancer drugs is now guided by a CDx. This central role of the CDx assays has attracted the attention of the regulators, and especially the US Food and Drug Administration has been at the forefront in relation to developing regulatory strategies for CDx and the drug-diagnostic co-development project. For an increasing number of cancer patients the treatment selection will depend on the result generated by a CDx assay, and consequently this type of assay has become critical for the care and safety of the patients. In order to secure that the CDx assays have a high degree of analytical and clinical validity, they must undergo an extensive non-clinical and clinical testing before release for routine patient management. This review will give a brief introduction to some of the scientific and medical challenges related to the CDx development with specific emphasis on the regulatory requirements in different regions of the world.
Secured Health Care Information exchange on cloud using attribute based encryption (2015)

Personal health record (PHR) is an emerging patient-centric model of health information exchange, which is often outsourced to be stored at a third party, such as cloud providers. This leads to address the privacy issues i.e., hide the sensitive health information of a patient, as the information can be accessible to unauthorized parties because of the nature of the storage. This paper describes novel patient-centric secure data sharing framework for cloud-based PHR systems. The paper is to create Health Care Information (HCIs) that are efficient and secure. HCIs can be stored in a third party cloud. The patients, who have created their profiles in the system, make their own HCIs, mentioning their disease, symptoms and other sufficient details. The doctors who are also a part of the system attend to the queries of the patients that have been updated in the cloud. The doctors' prescription is updated by the admin of the system, whereas the cloud admin has no access to the data. The level of encryption is considered before generating the encryption key. The record is then accessed using the key that the admin has generated. The health care services can look up to the user details. The details of the secured information remains encrypted, whereas the other details remain as updated.
Planar immersion lens with metasurfaces (2015)

The solid immersion lens is a powerful optical tool that allows light entering material from air or a vacuum to focus to a spot much smaller than the free-space wavelength. Conventionally, however, the lenses rely on semispherical topographies and are nonplanar and bulky, which limits their integration in many applications. Recently, there has been considerable interest in using planar structures, referred to as metasurfaces, to construct flat optical components for manipulating light in unusual ways. Here, we propose and demonstrate the concept of a planar immersion lens based on metasurfaces. The resulting planar device, when placed near an interface between air and dielectric material, can focus electromagnetic radiation incident from air to a spot in the material smaller than the free-space wavelength. As an experimental demonstration, we fabricate an ultrathin and flexible microwave lens and further show that it achieves wireless energy transfer in material mimicking biological tissue.
C3: an experimental, extensible, reconfigurable platform for HTML-based applications (2011)

The common conception of a (client-side) web application is some collection of HTML, CSS and JavaScript (JS) that is hosted within a web browser and that interacts with the user in some non-trivial ways. The common conception of a web browser is a monolithic program that can render HTML, execute JS, and gives the user a portal to navigate the web. Both of these are misconceptions: nothing inherently confines webapps to a browser's page-navigation idiom, and browsers can do far more than merely render content. Indeed, browsers and web apps are converging in functionality, but their underlying technologies are so far largely distinct.

We present C3, an implementation of the HTML/CSS/JS platform designed for web-client research and experimentation. C3's typesafe, modular architecture lowers the barrier to webapp and browser research. Additionally, C3 explores the role of extensibility throughout the web platform for customization and research efforts, by introducing novel extension points and generalizing existing ones. We discuss and evaluate C3's design choices for flexibility, and provide examples of various extensions that we and others have built.
Quenching of excited states by stable free radicals. II. Mechanism of triplet quenching by di-tert-butyl nitroxide (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuenching of excited states by stable free radicals. II. Mechanism of triplet quenching by di-tert-butyl nitroxideRobert E. Schwerzel and R. A. CaldwellCite this: J. Am. Chem. Soc. 1973, 95, 5, 1382–1389Publication Date (Print):March 1, 1973Publication History Published online1 May 2002Published inissue 1 March 1973https://pubs.acs.org/doi/10.1021/ja00786a005https://doi.org/10.1021/ja00786a005research-articleACS PublicationsRequest reuse permissionsArticle Views254Altmetric-Citations58LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Sequence requirements for self-splicing of the<i>Tetrahymena thermophila</i>pre-ribosomal RNA (1985)

The sequence requirements for splicing of the Tetrahymena pre-rRNA have been examined by altering the rRNA gene to produce versions that contain insertions and deletions within the intervening sequence (IVS). The altered genes were transcribed and the RNA tested for self-splicing in vitro. A number of insertions (8-54 nucleotides) at three locations had no effect on self-splicing activity. Two of these insertions, located at a site 5 nucleotides preceding the 3'-end of the IVS, did not alter the choice of the 3' splice site. Thus the 3' splice site is not chosen by its distance from a fixed point within the IVS. Analysis of deletions constructed at two sites revealed two structures, a hairpin loop and a stem-loop, that are entirely dispensable for IVS excision in vitro. Three other regions were found to be necessary. The regions that are important for self-splicing are not restricted to the conserved sequence elements that define this class of intervening sequences. The requirement for structures within the IVS for pre-rRNA splicing is in sharp contrast to the very limited role of IVS structure in nuclear pre-mRNA splicing.
Uniting aggregation-induced emission and stimuli-responsive aggregation-caused quenching, single molecule achieved multicolour luminescence (2019)

A single molecule uniting aggregation-induced emission and stimuli-responsive aggregation-caused quenching chromophores achieved mutilcolor luminescence.