gebhart/patrepeval huggingface dataset:
Riboprinting and 16S rRNA Gene Sequencing for Identification of Brewery <i>Pediococcus</i> Isolates (2001)

A total of 46 brewery and 15 ATCC Pediococcus isolates were ribotyped using a Qualicon RiboPrinter. Of these, 41 isolates were identified as Pediococcus damnosus using EcoRI digestion. Three ATCC reference strains had patterns similar to each other and matched 17 of the brewery isolates. Six other brewing isolates were similar to ATCC 25249. The other 18 P. damnosus brewery isolates had unique patterns. Of the remaining brewing isolates, one was identified as P. parvulus, two were identified as P. acidilactici, and two were identified as unique Pediococcus species. The use of alternate restriction endonucleases indicated that PstI and PvuII could further differentiate some strains having identical EcoRI profiles. An acid-resistant P. damnosus isolate could be distinguished from non-acid-resistant varieties of the same species using PstI instead of EcoRI. 16S rRNA gene sequence analysis was compared to riboprinting for identifying pediococci. The complete 16S rRNA gene was PCR amplified and sequenced from seven brewery isolates and three ATCC references with distinctive riboprint patterns. The 16S rRNA gene sequences from six different brewery P. damnosus isolates were homologous with a high degree of similarity to the GenBank reference strain but were identical to each other and one ATCC strain with the exception of 1 bp in one strain. A slime-producing, beer spoilage isolate had 16S rRNA gene sequence homology to the P. acidilactici reference strain, in agreement with the riboprint data. Although 16S rRNA gene sequencing correctly identified the genus and species of the test Pediococcus isolates, riboprinting proved to be a better method for subspecies differentiation.
Prostaglandin E2 and the Pathogenesis of Pulmonary Fibrosis (2011)

Prostaglandin (PG)E(2) is a bioactive eicosanoid that regulates many biologically important processes in part due to its ability to signal through four distinct G-protein-coupled receptors with differential signaling activity and unique expression patterns in different cell types. Although PGE(2) has been linked to malignancy in many organs, it is believed to play a beneficial role in the setting of fibrotic lung disease. This is in part due to the ability of PGE(2) to limit many of the pathobiologic features of lung fibroblasts and myofibroblasts, including the ability of PGE(2) to limit fibroblast proliferation, migration, collagen secretion, and, as originally reported in the Journal by us in 2003, the ability to limit transforming growth factor (TGF)-β-induced myofibroblast differentiation. In the setting of lung fibrosis, PGE(2) production and signaling is often diminished. In the last 8 years, significant advances have been made to better understand the dysregulation of PGE(2) production and signaling in the setting of lung fibrosis. We also have a clearer picture of how PGE(2) inhibits myofibroblast differentiation and the receptor signaling pathways that can influence fibroblast proliferation. This review highlights these recent advances and offers new insights into the potential ways that PGE(2) and its downstream signals can be regulated for therapeutic benefit in a disease that has no validated treatment options.
Auto-stereoscopic 3D displays with reduced crosstalk (2011)

In this paper, we propose new auto-stereoscopic 3D displays that substantially reduce crosstalk. In general, it is difficult to eliminate crosstalk in auto-stereoscopic 3D displays. Ideally, the parallax barrier can eliminate crosstalk for a single viewer at the ideal position. However, due to variations in the viewing distance and the interpupillary distance, crosstalk is a problem in parallax barrier displays. In this paper, we propose 3-dimensional barriers, which can significantly reduce crosstalk.
Detection of clonality by heteroduplex analysis of amplified junctional region of T-cell receptor gamma in patients with T-cell acute lymphoblastic leukemias. (1997)

Our heteroduplex analysis showed that separation of the PCR product by electrophoresis on non-denaturing PAGE is a rapid and convenient method for the detection of clonal TcR-gamma rearrangements in T-ALL.
A study of the Manipulability of the PHANToM OMNI Haptic Interface (2006)

When a haptic interface is going to be used as a part of a computational system a design criteria consist of maximizing the coincidence between the application 3D space and the physical volume where the haptic device provides the maximum performance. A well known parameter to evaluate the performance of a mechanical manipulator is the manipulability. This paper explains in detail the analysis of manipulability of the Phantom Omni haptic interface including the study of the manipulability distribution into its real workspace boundaries.
I-V Characteristics for Bifacial Silicon Solar Cell under a Magnetic Field (2007)

In this work, the influence of magnetic field on I-V characteristics of bifacial silicon solar cell n+-p-p+ structure is studied under constant multispectral illumination. After resolution of continuity equation related to photogenerated minority carriers’ density in the base region of this cell, MATLAB numerical simulations of excess minority carriers’, photocurrent densities and junction photovoltage profiles, have been developed with magnetic field in the bulk of the base region. In the same way, the IV characteristics have been studied with magnetic field. It has been demonstrated that the I–V characteristics decreased. It also has shown how the I–V characteristics changed.
In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression (2011)

These findings indicate that localized production of IL-22 in the liver promotes hepatocyte survival and proliferation but primes the liver to be more susceptible to tumor development without significantly affecting liver inflammation.
Monocular visual odometry for robot localization in LNG pipes (2011)

Regular inspection for corrosion of the pipes used in Liquified Natural Gas (LNG) processing facilities is critical for safety. We argue that a visual perception system equipped on a pipe crawling robot can improve on existing techniques (Magnetic Flux Leakage, radiography, ultrasound) by producing high resolution registered appearance maps of the internal surface. To achieve this capability, it is necessary to estimate the pose of sensors as the robot traverses the pipes. We have explored two monocular visual odometry algorithms (dense and sparse) that can be used to estimate sensor pose. Both algorithms use a single easily made measurement of the scene structure to resolve the monocular scale ambiguity in their visual odometry estimates. We have obtained pose estimates using these algorithms with image sequences captured from cameras mounted on different robots as they moved through two pipes having diameters of 152mm (6") and 406mm (16"), and lengths of 6 and 4 meters respectively. Accurate pose estimates were obtained whose errors were consistently less than 1 percent for distance traveled down the pipe.
Functional micro-ultrasound imaging of rodent cerebral hemodynamics (2011)

High-frequency ultrasound imaging has been developed to the point where it can be used to quantitatively image changes in the hemodynamic state of the rat brain upon stimulation. We used a nonlinear contrast imaging mode on a commercial micro-ultrasound system to image a microbubble contrast agent in the microvasculature of the living rat brain through a cranial window. Electrical stimulation of the forepaw resulted in quantifiable changes in local cerebral blood flow, both spatially (100 μm in-plane resolution) and temporally (40 ms resolution) in the imaging slice. We also show initial data on three-dimensional ultrasound imaging of blood flow in the mouse brain using color Doppler imaging. The experimental paradigm and data analysis methods we developed will be used in a study of microvascular malformation in a mouse model of Alzheimer's disease and should be useful for studies of neurodegenerative and neurovascular diseases in small animal models in general.
Anti—Nogo-A Antibody Infusion 24 Hours after Experimental Stroke Improved Behavioral Outcome and Corticospinal Plasticity in Normotensive and Spontaneously Hypertensive Rats (2003)

Nogo-A is a myelin-associated neurite outgrowth inhibitory protein limiting recovery and plasticity after central nervous system injury. In this study, a purified monoclonal anti-Nogo-A antibody (7B12) was evaluated in two rat stroke models with a time-to-treatment of 24 hours after injury. After photothrombotic cortical injury (PCI) and intraventricular infusion of a control mouse immunoglobulin G for 2 weeks, long-term contralateral forepaw function was reduced to about 55% of prelesion performance until the latest time point investigated (9 weeks). Forepaw function was significantly better in the 7B12-treated group 6 to 9 weeks after PCI, and reached about 70% of prelesion levels. Cortical infarcts were also produced in spontaneously hypertensive rats (SHR) by permanent middle cerebral artery occlusion (MCAO). In the control group, forepaw function remained between 40% and 50% of prelesion levels 4 to 12 weeks after MCAO. In contrast, 7B12-treated groups showed significant improvement between 4 and 7 weeks after MCAO from around 40% of prelesion levels at week 4 to about 60% to 70% at 7 to 12 weeks after MCAO. Treatment in both models was efficacious without influencing infarct volume or brain atrophy. Neuroanatomically in the spinal cord, a significant increase of midline crossing corticospinal fibers originating in the unlesioned sensorimotor cortex was found in 7B12-treated groups, reaching 2.3 +/- 1.5% after PCI (control group: 1.1 +/- 0.5%) and 4.5 +/- 2.2% after MCAO in SHR rats (control group: 1.8 +/- 0.8%). Behavioral outcome and the presence of midline crossing fibers in the cervical spinal cord correlated significantly, suggesting a possible contribution of the crossing fibers for forepaw function after PCI and MCAO. The results suggest that specific anti-Nogo-A antibodies bear potential as a new rehabilitative treatment approach for ischemic stroke with a prolonged time-to-treatment window.
Plasma contact activation: a revised hypothesis. (1998)

A new hypothesis for activation of the contact system of plasma proteolysis (i.e., the plasma kallikrein/kinin system) is presented. Kininogens have a multiprotein receptor on endothelial cells which consists of at least cytokeratin 1, urokinase plasminogen activator receptor, and gC1qR. When contact proteins (high molecular weight kininogen followed by prekallikrein) assemble on the kininogen receptor on endothelial cells, an endothelial cell membrane cysteine protease is expressed to activate prekallikrein to kallikrein. On endothelial cells, prekallikrein activation is independent of factor XIIa activation. Activation of prekallikrein on endothelial cells results in kallikrein cleaving its receptor high molecular weight kininogen to liberate bradykinin. Bradykinin liberation stimulates release of tissue-type plasminogen activator from endothelial cells. Kallikrein formation also results in kinetically favorable pro-urokinase activation on endothelial cells with subsequent plasminogen activation. In addition to stimulating cellular fibrinolysis, kininogens contribute to the constitutive anticoagulant nature of the intravascular compartment. Kininogens block calpain's participation in forming the heterodimeric complex of platelet integrin alpha IIb beta 3. Kininogens also block thrombin from binding to the thrombin receptor(s) on platelets. Last, kininogens prevent thrombin from cleaving protease activated receptor 1 after arginine41. These combined data indicate a biologic system for activation of the plasma kallikrein/kinin system and physiologic consequences as result of this activation.
A 2-D VIPA-grating pulse shaper with a liquid crystal on silicon (LCOS) spatial light modulator for broadband, high resolution, programmable amplitude and phase control (2010)

We demonstrate programmable amplitude and phase shaping with simultaneous broad-bandwidth(>;40nm) and high-resolution(~3.3GHz) using a 2-D VIPA-Grating pulse-shaper with a 2-D LCOS SLM. We demonstrate results with sources having continuous spectra and with optical frequency combs.
VELOC: a new kind of information system (2003)

Based on the Global Positioning System (GPS), VELOC (vehicle location) is designed to be a vehicle information system for fleet management adaptable to various user groups, e.g., haulage and delivery companies, and service enterprises with vehicle fleets. The needs of these groups vary with respect to position accuracy, position update rate, and type of communication. The authors describe the requirements, specifications, and performance of VELOC. Special emphasis is placed on some substantial features of the VELOC center, namely the integration of DGPS, a comfortable user interface, and handling of vehicle positions on digital maps.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A new fast Reed-Solomon decoding algorithm without Chien search (2002)

This paper presents a novel Reed-Solomon (RS) decoding algorithm based on finite fields with an infinite element. The Chien Search procedure included in all existing general RS decoding algorithms can be totally eliminated in this new method. Hence it can reduce the decode time significantly. Comparisons with other RS decoding methods and hardware structure of this new algorithm are also discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison. (2000)

Chloroquinoxaline sulfonamide (chlorosulfaquinoxaline, CQS, NSC 339004) is active against murine and human solid tumors. On the basis of its structural similarity to the topoisomerase IIbeta-specific drug XK469, CQS was tested and found to be both a topoisomerase-IIalpha and a topoisomerase-IIbeta poison. Topoisomerase II poisoning by CQS is essentially undetectable in assays using the common protein denaturant SDS, but easily detectable with strong chaotropic protein denaturants. The finding that detection of topoisomerase poisoning can be so dependent on the protein denaturant used in the assay has implications for drug discovery efforts and for our understanding of topoisomerase poisons.
NAVIGATION SYSTEMS. FUNDAMENTALS OF LOW- AND VERY-LOW-FREQUENCY HYPERBOLIC TECHNIQUES (1970)

Low-frequency and very-low-frequency hyperbolic navigation systems are becoming of increasing importance in the world community. The three most widely used of this category of systems are Decca, Loran C/D and Omega. The paper describes the fundamentals of each of these systems and the extent of the present and announced planned ground implementation of the Loran C and Omega.
Polyimides : materials, chemistry, and characterization : proceedings of the Third International Conference on Polyimides, Ellenville, New York, November 2-4, 1988 (1989)

The scope of this book is to give an up-to-date overview of the field of polyimide research - a field which has seen rapid growth and diversification in the last few years as well as a stronger involvement of university laboratories. Although synthesis of new materials still plays a major role, a number of groups work now on understanding the details of polyimide chemistry, structure and properties. This is reflected in the papers presented in this book which examine several major aspects of polyimides: new materials, synthesis, cure studies, structure-property studies, studies of mechanical and electrical properties, analysis of polyimides, interface studies, and applications. The papers, too numerous to list individually, are grouped under the following headings: 1. New Materials (18 papers) : includes polyimide blends (a new field), photosensitive polyimides, silicon-containing polyimides, copolymers, bismaleimide resins, semi-interpenetrating networks. 2. Synthesis (6 papers): includes new synthetic methods, polymerization mechanisms and properties of precursor solutions. 3.
A comparison of input devices in element pointing and dragging tasks (1991)

An experiment is described comparing three devices (a mouse, a trackball, and a stylus with tablet) in the performance of pointing and dragging tasks. During pointing, movement times were shorter and error rates were lower than during dragging.
Stress induction of the mammalian GRP78/BiP protein gene: in vivo genomic footprinting and identification of p70CORE from human nuclear extract as a DNA-binding component specific to the stress regulatory element. (1994)

GRP78, also known as BiP, is one of the better-characterized molecular chaperones. It has been implicated in protein folding and also calcium sequestration in the endoplasmic reticulum. When the cells are subjected to endoplasmic reticulum stress, in particular the depletion of stored calcium and/or the accumulation of abnormal proteins, the rate of transcription of grp78 is enhanced. Previous studies have shown that the core region of the rat grp78 promoter (-170 to -135), which is 95% conserved with the human grp78 core (-133 to -98), is one of the key regulatory elements. Using ligation-mediated PCR, we have found that there are specific changes in factor occupancy after stress induction and the major changes occur within a cluster of bases located in the 3' half of the grp core, whereas other regulatory elements are constitutively occupied. This inducible binding to the 3' half of the human grp78 core region is observed under diverse stress signals, suggesting a common mechanism for the grp stress response. Nonetheless, the lack of constitutive in vivo protection at this region is not due to the absence of a binding factor in nuclear extracts. Using in vitro gel mobility shift assays, we detected a constitutive binding activity which exhibits specificity and affinity to the stress-inducible region. Through sodium dodecyl sulfate-polyacrylamide gel electrophoresis size fractionation and renaturation analysis, the activity is found in polypeptides with molecular sizes of 65 to 75 kDa. After a three-step purification scheme including core affinity column chromatography, we purified p70CORE, which is about 70 kDa in its monomeric form. The purified p70CORE is sufficient to form a complex specific to the stress-inducible region.
High-current ion implanter using a microwave ion source (1983)

A new ion implanter has been designed for high-dose predeposition in a semiconductor production line. It incorporates a microwave ion source, a 90° magnetic mass separator, and a rotating disk target chamber. Mass peak variations of PH3 gas are shown as a function of the incident microwave power. The ion energy level can be varied from 10 to 50 keV. It makes 10 mA P+ implantation (maximum 15 mA) possible. After beam adjustment, implantation is automatically carried out with a microcomputer. The operation rate of the implanter is remarkably improved due to the long lifetime of the modified microwave ion source and the low gas consumption. The dose nonuniformity of a 3-in. wafer implanted with this implanter has a standard deviation (σ) of 0.5%. This small nonuniformity results in a small σ in the transistor current gain (less than 3.5%).
THE GROWTH OF ADULT HUMAN SKIN IN VITRO (1972)

Summary.— In this report we investigate the role of serum in organ culture of adult human skin. The migratory overgrowth of dermis by epidermal cells is shown to depend on the presence of high molecular weight (mol. wt.) components of serum. Regeneration of the epidermis after 19 days' incubation occurs in the presence of 10% whole serum in the growth medium. DNA synthesis is found to increase in long‐term incubations in medium including serum components but not in the presence of Minimal Essential Medium (MEM) only.
Photocatalysis of Yttrium Doped BaTiO<sub>3</sub> Nanofibres Synthesized by Electrospinning (2015)

Yttrium doped barium titanate (BT) nanofibres (NFs) with significant photocatalytic effect were successfully synthesized by electrospinning. Considering the necessary factors for semiconductor photocatalysts, a well‐designed procedure was carried out to produce yttrium doped BT (BYT) NFs. In contrast to BYT ceramics powders and BT NFs, BYT NFs with pure perovskite phase showed much enhanced performance of photocatalysis. The surface modification in electrospinning and subsequent annealing, the surface spreading of transition metal yttrium, and the narrowed band gap energy in yttrium doping were all contributed to the final novel photocatalytic effect. This work provides a direct and efficient route to obtain doped NFs, which has a wide range of potential applications in areas based on complex compounds with specific surface and special doping effect.
Tessellated Shading Streaming (2019)

Abstract Presenting high‐fidelity 3D content on compact portable devices with low computational power is challenging. Smartphones, tablets and head‐mounted displays (HMDs) suffer from thermal and battery‐life constraints and thus cannot match the render quality of desktop PCs and laptops. Streaming rendering enables to show high‐quality content but can suffer from potentially high latency. We propose an approach to efficiently capture shading samples in object space and packing them into a texture. Streaming this texture to the client, we support temporal frame up‐sampling with high fidelity, low latency and high mobility. We introduce two novel sample distribution strategies and a novel triangle representation in the shading atlas space. Since such a system requires dynamic parallelism, we propose an implementation exploiting the power of hardware‐accelerated tessellation stages. Our approach allows fast de‐coding and rendering of extrapolated views on a client device by using hardware‐accelerated interpolation between shading samples and a set of potentially visible geometry. A comparison to existing shading methods shows that our sample distributions allow better client shading quality than previous atlas streaming approaches and outperforms image‐based methods in all relevant aspects.