gebhart/patrepeval huggingface dataset:
Oil recovery and waste reduction by microwave radiation (1989)

Abstract Oil‐in‐water and oil‐water‐solid emulsions, by‐products of various industrial operations, often are environmental concerns. Laboratory and field tests have shown that these emulsions can be demulsified and separated into their individual layers by microwave radiation. The data also show that microwave separation is faster than gravity separation and can be faster than conventnal heating at many conditions. After separation of emulsion into water, slop and oil layers, water can be discharged and oil is collected for recycle. The volume of slop is much smaller than the original volume of emulsion, therefore, the oily waste to be disposed is greatly reduced. The zeta potential of oily droplets in water was measured and found that it is reduced by microwave radiation. This indicates that microwave provides heating and reduction of zeta potential in demulsification.
Design, synthesis, and biological evaluation of thieno[3,2‐d]pyrimidine derivatives as potential simplified phosphatidylinositol 3‐kinase alpha inhibitors (2018)

Abstract A series of thieno[3,2‐d]pyrimidine derivatives as phosphatidylinositol 3‐kinase (PI3K) inhibitors was designed using the combination strategy. The synthesis and biological evaluation of the derivatives demonstrated their potent inhibition of PI3K, culminating in the discovery of 7 and 21 . Determination of a co‐crystal structure of 7 complexed with PI3Kα provided the structural basis for the high enzymatic activity. Furthermore, cellular investigation of compounds 7 and 21 revealed that they efficiently suppressed cancer cell lines proliferation through inhibition of intracellular PI3K/AKT/mammalian target of rapamycin pathway. The results provided potent simplified inhibitors of PI3K with a promising overall profile and a chemical series for further optimization to progress into vivo experiments.
High Pressure Effects in Molecular Biophysics and Enzymology (1996)

High Pressure Effects in Molecular Biophysics and Enzymology is designed to acquaint biochemists, biophysicists, and graduate students with advances in the application of high pressure in connection with spectroscopy as a research tool in the study of biomolecules. The 23 chapters written by leading authorities present an overview of current approaches to the use of high pressure in research on enzyme kinetics, protein folding and structure, lipid bilayer structure and organization, lipid-protein interaction, and DNA structure. This important, timely volume is the first devoted exclusively to high-pressure effects in biochemistry and will be the definitive reference in its subject for the next several years.
Celeribacter indicus sp. nov., a polycyclic aromatic hydrocarbon-degrading bacterium from deep-sea sediment and reclassification of Huaishuia halophila as Celeribacter halophilus comb. nov. (2014)

A taxonomic study was carried out on strain P73(T), which was isolated from deep-sea sediment of the Indian Ocean by enrichment of polycyclic aromatic hydrocarbons. The strain was able to degrade biphenyl, naphthalene, 2-methylnaphthalene, 2,6-dimethylnaphthalene, acenaphthene, anthracene, phenanthrene, dibenzothiophene, dibenzofuran, fluorene, 4-methyldibenzothiophene and fluoranthene, but not pyrene or chrysene. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain P73(T) formed a clade with the genera Celeribacter and Huaishuia within the family Rhodobacteraceae, with highest sequence similarity of 96.98 % to Celeribacter neptunius H 14(T), followed by Huaishuia halophila ZXM137(T) (96.42 %). The bacterium was Gram-stain-negative, oxidase- and catalase-positive, rod-shaped and non-motile. Growth was observed at salinities from 0.5 to 12 % and at temperatures from 10 to 41 °C. The principal fatty acids (>10 %) of strain P73(T) were summed feature 8 (C18 : 1ω7c/ω6c) and C19 : 0ω8c cyclo. The sole respiratory quinone was Q-10. The major lipids were phosphatidylglycerol, one unknown aminolipid, one unknown phospholipid and one unknown lipid; a second unknown phospholipid and one unknown glycolipid were present as minor components. The G+C content of the chromosomal DNA was 66.0 mol%. The combined genotypic and phenotypic data show that strain P73(T) represents a novel species of the genus Celeribacter, for which the name Celeribacter indicus sp. nov. is proposed. The type strain is P73(T) ( = MCCC 1A01112(T) = LMG 27600(T) = DSM 27257(T)). Phylogenetic study and existing phenotypic information also show that Huaishuia halophila should be transferred to the genus Celeribacter as Celeribacter halophilus comb. nov. (type strain ZXM137(T) = MCCC 1A06432(T) = CGMCC 1.8891(T) = LMG 24854(T)).
Influence of Droplet Characteristics on the Formation of Oil-in-Water Emulsions Stabilized by Surfactant−Chitosan Layers (2005)

The objective of this study was to establish the optimum conditions for preparing stable oil-in-water emulsions containing droplets surrounded by surfactant-chitosan layers. A primary emulsion containing small droplets (d32 approximately = 0.3 microm) was prepared by homogenizing 20 wt% corn oil with 80 wt% emulsifier solution (20 mM SDS, 100 mM acetate buffer, pH 3) using a high-pressure valve homogenizer. The primary emulsion was diluted with chitosan solutions to produce secondary emulsions with a range of oil and chitosan concentrations (0.5-10 wt% corn oil, 0-1 wt% chitosan, pH 3). The secondary emulsions were sonicated to help disrupt any droplet aggregates formed during the mixing process. The electrical charge, particle size, and amount of free chitosan in the emulsions were then measured. The droplet charge changed from negative to positive as the amount of chitosan in the emulsions was increased, reaching a relatively constant value (approximately +50 mV) above a critical chitosan concentration (C(Sat)), which indicated that saturation of the droplet surfaces with chitosan occurred. Extremely large droplet aggregates were formed at chitosan concentrations below C(Sat), but stable emulsions could be formed above C(Sat) provided the droplet concentration was not high enough for depletion flocculation to occur. Interestingly, we found that stable multilayer emulsions could also be formed by mixing chitosan with an emulsion stabilized by a nonionic surfactant (Tween 20) due to the fact the initial droplets had some negative charge. The information obtained from this study is useful for preparing emulsions stabilized by multilayer interfacial layers.
Suplphur Regulation – technology solutions and economic consequences for the Baltic Sea Region shipping market (2016)

The aim of this publication is to give an accurate overview of the shipping market,\nespecially in the Baltic Sea Region, which we judge to be most seriously affected by the Sulphur Regulation. The overview consists of a technical part in which the most popular and most probable solutions that shipping owners will undertake and invest in are presented. The second part concerns the economic consequences of specific, chosen technologies with special attention given to the cost analysis of them and the potential impact on the transportation market, which will affect freight rates and tariffs directly in the shipping industry and indirectly in the rail and road transport sector.
Susceptibility of cancer cells to herpes simplex virus-dependent apoptosis (2007)

Apoptosis has recently been associated with herpes simplex virus 1 (HSV-1) latency and disease severity. There is an intricate balance between pro- and anti-apoptotic processes during HSV-1 infection. When anti-apoptotic pathways are suppressed, this balance is upset and the cells die by apoptosis, referred to here as HSV-1-dependent apoptosis (HDAP). It has been observed previously that HeLa cancer cells exhibit an enhanced sensitivity to HDAP. Here, a series of specific patient-derived cancer cells was utilized to investigate the cell-type specificity of HDAP. The results showed that a human mammary tumour cell line was sensitive to HDAP, whilst syngeneic normal cells were resistant. Furthermore, low-passage-number primary human mammary epithelial cells were resistant to HDAP. When the susceptibility of human colon, brain, breast and cervical cancer cells was assessed, the only cells insensitive to HDAP were those resistant to all environmental stimuli tested. This implies that the HDAP resistance was probably due to mutations in the cellular apoptotic machinery. Thus, the susceptibility of cancer cells to HDAP requires that they possess a functional ability to undergo programmed cell death.
Advanced NDT methods for the assessment of concrete structures (2008)

It became clear very early that ultrasonic pulse echo on concrete requires very low frequency transducers (Neisecke 1991) to overcome the scattering problem in coarse aggregate concrete. Multi position experiments and synthetic aperture data analysis led to reliable thickness measurements of concrete slabs. In order to reduce testing times and to ease experiments, arrays of ten transducers were used. In the mid 90s a new type of transducer was developed in Russia (www.acsys.ru 2006) which did not require special coupling to the concrete surface (Fig. 1). Based on transversal excited ultrasound, testing became much easier to perform with the availability of these commercial products. The individual transducers have ceramic pin contact to the concrete, 12 transducers each are combined and form a large aperture for transmitting and receiving the signals.
Improved global rational approximation macromodeling algorithm for networks characterized by frequency-sampled data (2000)

Recently, the demand for high-performance wireless designs has been increasing while simultaneously the speed of high-end digital designs have crossed over the gigahertz range. New simulation tools which accurately characterize high-frequency interconnects are needed. This paper presents improvements to a new macromodeling algorithm. The algorithm employs curve-fitting techniques to achieve a pole-residue approximation of the frequency-sampled network. The frequency sampled S-parameters or Y-parameters can be obtained from measurement or full-wave simulation to characterize the frequency-dependent interconnects behavior. The improvements extend the approach to lossless structures, increase its accuracy with pole-clustering, and ensure its validity with a passivity test. This paper addresses some of the special considerations that must be made to the method so it can efficiently and accurately be applied to lossless circuits and structures. The resulting algorithm is now capable of accurately extracting a wide-band frequency domain macromodel from frequency-sampled data for either LC circuit (lossless) or RLC circuits (lossy). The frequency-domain macromodel can be linked to a SPICE circuit simulator for mixed signal circuit analysis using RF, analog, and digital circuits. The circuit can be simulated in the time domain using recursive convolution.
Design of Multi-Wavelength Micro Raman Spectroscopy System and Its Semiconductor Stress Depth Profiling Applications (2009)

Design concepts of a newly developed multi-wavelength, micro Raman spectroscopy system for non-contact and non-destructive characterization of semiconductor materials and its performance are introduced. The system is designed to sequentially measure Raman signals under various excitation wavelengths without sample movement or calibration between switching of excitation wavelengths. Area maps of Raman shift, full-width-at-half-maximum (FWHM) and intensity from an advanced memory device were generated and stacked in the order of wavelength (or penetration depth). This unique display of Raman shift, FWHM and intensity, corresponding to crystalline stress, crystallinity and/or scattering probability provides powerful insights into the sample under characterization.
Subjective quality assessment of Screen Content Images (2014)

Research on Screen Content Images (SCIs) becomes important as they are increasingly used in multi-device communication applications. In this paper, we present a study of subjective quality assessment for distorted SCIs, and investigate which part (text or picture) contributes more to the overall visual quality. We construct a large-scale Screen Image Quality Assessment Database (SIQAD) consisting of 20 source and 980 distorted SCIs. The 11-category Absolute Category Rating (ACR) is employed to obtain three subjective quality scores corresponding to the entire image, textual and pictorial regions respectively. Based on the subjective data, we investigate the applicability of 12 state-of-the-art Image Quality Assessment (IQA) methods for objectively assessing the quality of SCIs. The results indicate that existing IQA methods are limited in predicting human quality judgement of SCIs. Moreover, we propose a prediction model to account for the correlation between the subjective scores of textual and pictorial regions and the entire image. The current results make an initial move towards objective quality assessment of SCIs.
Perfil antropométrico de alunos de dança de salão: uma análise comparativa (2012)

Introduction: Currently the dance hall has been widely publicized, either by the media as the appeal that it promotes socialization for the visitors. Objective: This study aimed to ascertain the anthropometric profile of students who do ballroom dancing, compared to sedentary individuals. Materials, Methods and Results: For the study, a population of 22 (n = 22) subjects. 11 individuals GD (average 70.42 kg, SD 9.46) and 11 GS (average 74.15 kg, SD 9.89). Submitted to CC values for GD group (mean 92.68 cm, SD 11.14 cm) and GS (average 94.05 cm, SD 10.59 cm) in the analysis for the RCQ groups pointed GD (average 0.88 and SD 0.12) and GS (mean 0.86, SD 0.07), IMC GD (mean 28.36 kg/m2, SD 3.19), GS (mean 28.75 kg/m2, SD 4, 12) IC, GD (mean 1.27, SD 0.13),GS (mean 1.27 and SD 0.19). was used for hypothesis testing, the t-student test simple independent, with p <0.05 as the minimum level of significance and Chi square and odds ratio (OR) with a score of 95% to analyze the relationship between overweight by IMC in Groups and the relationship between sedentary lifestyle and practicing ballroom dancing. Conclusion: It refers to the results obtained by anthropometric protocols was found that no significant differences between groups, indicating that ballroom dancing does not promote significant changes in body composition.
Quantitative Analysis of Ingenol in <i>Euphorbia</i> species via Validated Isotope Dilution Ultra‐high Performance Liquid Chromatography Tandem Mass Spectrometry (2017)

The newly established UHPLC-MS/MS method shows to be an appropriate tool for screening of the Euphorbia genus for ingenol content and allows selection of species suitable for raw material production and/or in vitro culture initiation. Copyright © 2017 John Wiley & Sons, Ltd.
Ribozyme-targeting procathepsin D and its effect on invasion and growth of breast cancer cells: An implication in breast cancer therapy (2007)

Procathepsin D (pCD), a zymogen of lysosomal aspartic peptidase cathepsin D, overexpression is correlated with highly invasive malignancies, including breast cancer. Recently, different studies have shown the role of secreted pCD as mitogen acting both in an autocrine and a paracrine manner. The aim of the present study is to examine the anti-tumor effects elicited by a decrease in the protein level of pCD by ribozyme and to explore the therapeutic potential of this specific targeting. Using the mFold program, we designed seven anti-pCD ribozymes and checked the accessibility to target pCD mRNA by RNase H cleavage experiment in a cell-free system. The sequences of the 4 most effective ribozymes were cloned and stably transfected in a highly metastatic human breast cancer cell line, MDA-MB-231, to knock down the expression of pCD. Downregulation of pCD due to ribozyme expression was observed by Western blotting and real-time RT-PCR. Stably transfected cells with anti-pCD ribozymes exhibited a significant lowering of in vitro invasion (p<0.001) and reduction in lung colonization potential in nude mice when compared to control ribozyme transfected cells. We also found that downregulation of pCD by ribozyme promotes apoptosis of MDA-MB-231 cells on serum deprivation. These results suggest that we have generated a biologically functional ribozyme against pCD with possible therapeutic implications in breast cancer cells.
Fixed frequency forward-flyback converter with two fully regulated outputs (2002)

Multiple output power converters are widely used in telecommunications equipment when several voltages are needed. These power converters are smaller and cheaper than various individual converters. However, it is very difficult to obtain multioutput power converters with high efficiency and tight regulation. To overcome these difficulties, a new technique has been developed and is presented in this article. This technique consists on a forward/flyback topology with active clamp where the forward output is regulated with the duty cycle of the main switch and the flyback output is regulated with the duty cycle of the auxiliary switch. Experimental results for a +5 V/20 A, -5 V/12.5 A power converter show efficiencies at full load higher than 87% and a switching frequency of 175 kHz. This solution introduces few additional components, but nevertheless the advantages versus other regulation techniques are not only in efficiency but also in volume and cost.
Dysregulation of Cholesterol Homeostasis in Human Prostate Cancer through Loss of <i>ABCA1</i> (2012)

Recent epidemiologic data show that low serum cholesterol level as well as statin use is associated with a decreased risk of developing aggressive or advanced prostate cancer, suggesting a role for cholesterol in aggressive prostate cancer development. Intracellular cholesterol promotes prostate cancer progression as a substrate for de novo androgen synthesis and through regulation of AKT signaling. By conducting next-generation sequencing-based DNA methylome analysis, we have discovered marked hypermethylation at the promoter of the major cellular cholesterol efflux transporter, ABCA1, in LNCaP prostate cancer cells. ABCA1 promoter hypermethylation renders the promoter unresponsive to transactivation and leads to elevated cholesterol levels in LNCaP. ABCA1 promoter hypermethylation is enriched in intermediate- to high-grade prostate cancers and not detectable in benign prostate. Remarkably, ABCA1 downregulation is evident in all prostate cancers examined, and expression levels are inversely correlated with Gleason grade. Our results suggest that cancer-specific ABCA1 hypermethylation and loss of protein expression direct high intracellular cholesterol levels and hence contribute to an environment conducive to tumor progression.
Irx4 identifies a chamber‐specific cell population that contributes to ventricular myocardium development (2013)

Given the ventricle-specific expression of Irx4 in later stages of heart development, we hypothesize that IRX4+ cells in the cardiac crescent represent the earliest cell population in the cellular hierarchy underlying ventricular myocardium development.
GaAs power FET for K-band operation (1981)

A report on a 1.35mm gatewidth GaAs power FET that has produced 675mW with 5.8dB gain at 20.5GHz as an amplifier and 200mW at 25GHz as an oscillator, will be presented.
Spatiotemporal Stochastic Resonance in a System of Coupled Diode Resonators (1996)

Recently, the phenomenon of array enhanced stochastic resonance was demonstrated via numerical simulations by Lindner et al. [Phys. Rev. Lett. 75, 3 (1995)]. We present experimental evidence that the signal-to-noise ratio (SNR) of the output signal of a single diode resonator can be significantly improved by coupling it diffusively into an array of up to 32 nonidentical resonators. It is shown that the maximum SNR coincides with optimal spatiotemporal synchronization of the chain. We briefly address the connection between spatiotemporal stochastic resonance and the presence of kink-antikink pairs in the array.
Preparation and Electrochemical Performance of Spinel-Type Compounds Li[sub 4]Al[sub y]Ti[sub 5−y]O[sub 12] (y=0, 0.10, 0.15, 0.25) (2004)

and doped 0.15, 0.25) were synthesized via solid-state reaction using -rutile, and as starting reagents. The charge-discharge cycling of the cells showed that the electrochemical performance of prepared from rutile-type by our laboratory was as good as that produced by anatase-type However, doped exhibited a much better electrochemical performance in comparison with undoped Among the three samples of exhibited the largest reversible capacity and the highest coulombic efficiency. The discharge capacity values in the first and second cyclings were 195.6 and 173.6 mAh/g, respectively. The value remained 166.9 mAh/g after 30 cycles with a capacity loss of 3.86% compared to the second cycle, and the coulombic efficiency was 99.2% at the 30th cycle. © 2004 The Electrochemical Society. All rights reserved.
Streptomyces thinghirensis sp. nov., isolated from rhizosphere soil of Vitis vinifera (2009)

A novel actinomycete, strain S10T, was isolated from rhizosphere soil of wild Vitis vinifera in Thinghir, Ouarzazate Province, Southern Morocco. The taxonomic status of this strain was established using a polyphasic approach. Strain S10T had white–grey aerial mycelium with long, spiral spore chains bearing smooth surfaced spores and produced a yellow diffusible pigment. Chemotaxonomic analyses showed that the cell wall of strain S10T contained ll-diaminopimelic acid and glycine. Phylogenetic analysis based on the almost complete 16S rRNA gene sequence indicated that strain S10T belonged to the Group I streptomycetes, branching off next to Streptomyces marokkonensis LMG 23016T from the Streptomyces violaceoruber group. DNA–DNA relatedness and phenotypic data distinguished strain S10T from the phylogenetically closest related type strains. It is therefore proposed that strain S10T (=CCMM B35T=DSM 41919T) represents the type strain of a novel species of the genus Streptomyces, for which the name Streptomyces thinghirensis sp. nov. is proposed.
Speaker Verification Using Sequence Discriminant (2005)

This paper presents a text-independent speaker veri- fication system using support vector machines (SVMs) with score- space kernels. Score-space kernels generalize Fisher kernels and are based on underlying generative models such as Gaussian mix- ture models (GMMs). This approach provides direct discrimina- tion between whole sequences, in contrast with the frame-level ap- proaches at the heart of most current systems. The resultant SVMs have a very high dimensionality since it is related to the number of parameters in the underlying generative model. To address prob- lems that arise in the resultant optimization we introduce a tech- nique called spherical normalization that preconditions the Hes- sian matrix. We have performed speaker verification experiments using the PolyVar database. The SVM system presented here re- duces the relative error rates by 34% compared to a GMM likeli- hood ratio system.