gebhart/patrepeval huggingface dataset:
The position of the occlusal plane in dentulous subjects with various skeletal jaw‐relationships (1988)

Summary This study was conducted to examine the level and inclination of the occlusal plane in dentulous subjects with various skeletal jaw‐relationships with the purpose of finding more reliable guides for locating the occlusal plane in edentulous patients. The investigation was carried out on 140 lateral cephalometric radiographs of young people with natural teeth in the intercuspal position. The sample was divided into three groups according to the skeletal relation of the jaws. The occlusal plane in this study and the two reference planes (maxillary and mandibular plane) were established according to the cephalometric criteria of Schwarz. On each radiograph both the angulation and the perpendicular distance of the occlusal plane to the reference planes were recorded and the values of the obtained data were subject to statistical analysis. The selected mean values of the angles and linear distances between the occlusal plane and reference planes calculated on the probability level of 95% could be used as cephalometric indicators for the locating or correcting the position of the occlusal plane in the prosthetic treatment of edentulous patients.
A practical SDMA protocol for 60 GHz millimeter wave communications (2008)

We study spatial division multiple access in 60 GHz millimeter wave communications and focus on estimation of the optimal transmit beamforming vectors for stations and optimal receive beamforming vectors for the access point. An iterative antenna training protocol is developed, where the optimal transmit/ receive beamforming vectors are computed without explicit knowledge of the actual wireless channels. The proposed training method is especially attractive to systems with a much smaller number of RF chains relative to the number of antenna elements, thanks to its low training overhead.
A facile one-step way to anchor noble metal (Au, Ag, Pd) nanoparticles on a reduced graphene oxide mat with catalytic activity for selective reduction of nitroaromatic compounds (2013)

A facile, one-step clean strategy has been utilized for anchoring noble metal (Au, Ag, Pd) nanoparticles onto the flat surface of two-dimensional (2D) graphene oxide (GO) nanosheets. Without using any additional reductants, surfactants or protecting ligands, the deposition of metallic noble metal (Au, Ag, Pd) nanoparticles on the partially reduced graphene oxide (PRGO) mat has been realized by a simple redox reaction between the noble metal precursors and GO in an aqueous solution. The main size distributions of the Au, Ag and Pd particles are centered on 1–20 nm, 3–10 nm and 0.5–3 nm, respectively. The as-obtained Au, Ag and Pd–PRGO nanocomposites display superb catalytic activities for the selective reduction of nitroaromatic compounds into the corresponding amino compounds under ambient conditions. The rates of reduction follow the sequence, Pd–PRGO > Ag–PRGO > Au–PRGO, suggesting that the smallest noble metal particles size affords the highest catalytic activity. In addition, considering that the Au, Ag and Pd–PRGO nanocomposites still hold the abundant functional groups of the original GO, these noble metal–PRGO composites maintain the excellent hydrophilic nature of GO, which provides a flexible platform for the further fabrication of PRGO–metal-based multicomponent functional materials by a wet-chemistry approach.
Circulating Mitochondrial Nucleic Acids Have Prognostic Value for Survival in Patients with Advanced Prostate Cancer (2007)

Quantification of plasma mitochondrial nucleic acids may be used to recognize patients with a poor prognosis. In advanced prostate cancer patients, mtRNA seemed the strongest predictor of overall survival and an independent prognostic factor for cancer-related death. Amplification of mitochondrial nucleic acids shows increased sensitivity and specificity over genomic DNA as diagnostic and prognostic marker in prostate cancer patients.
Carbon Black - Polyethylene Composites for PTC (Positive Temperature Coefficient) Thermistor Applications (1987)

Abstract : A new class of composite Positive Temperature Coefficient (PT C) thermistors are commercially available. These composite thermistors exhibit a PTC measuring 6-8 orders of magnitude and have several advantages over conventional Barium Titanate 3 thermistors, including lower room temperature resistivity, better thermal shock resistance, and high temperature stability. In this study, composite PTC thermistors are produced from a carbon black/ polyethylene composition that exhibited a PTC of resistance measuring 6-8 orders of magnitude at 125 C. The composites are irradiated (gamma source) to induce polymer crosslinking. Crosslinking imparts mechanical integrity and prevents the onset of an NTC effect above the transition temperature. Crosslinking stabilizes the high temperature resistivity to 200 C. The electrical properties of these crosslinked composites are examined as functions of temperature, frequency, and thermal cycling. To eliminate the crosslinking procedure, an insulating mullite phase was incorporated into the diphasic mixture to form a triphasic composite. Addition of the third filler yielded two effects. First, the filler provided sufficient mechanical stabilization of the composite structure to maintain high post-PTC resistance without an NTC effect. Second, the addition of an insulating filler resulted in a shift of the room temperature resistivity caused by a shift in the percolation curve. (KT)
Effect of sidespin and wind on projectile trajectory, with particular application to golf (1988)

This article describes the computer simulation of the three-dimensional projectile motion of a spinning golf ball subjected to aerodynamic effects. Linear lift and drag forces are employed in the mathematical model and shown to be physically valid for launch conditions typical of a drive with a 1-wood. The effects of sidespin and wind are also included in the model, and an analytical solution of the dynamic equations of motion is obtained. This solution has been encoded in a fortran-77 program to provide rapid computation of trajectories, and graphical plots are presented that clearly illustrate the resulting ‘‘slicing’’ or ‘‘hooking’’ motion. Finally, the effects of various combinations of sidespin and crosswind on the final ball position are presented. Specifically, it is shown that a ball hit with sidespin into a crosswind can fly farther than it could in conditions of no wind.
AZT EFFECT ON THE BONE MARROW — A NEW PERSPECTIVE ON THE CONCORDE TRIAL (1995)

The Concorde trial shows an increase in CD4 + lymphocytes, but not a higher survival, in AZT treated asymptomatic patients. Our murine bone-marrow experiments show that in chronic AZT treatments a large increase in the lymphoids/erythroids compartment is due to host cytotoxicity. We put forward a mathematical formula for predicting cytotoxicity of given drug protocols, which can be used for modulating the schedule so as to increase its efficacy while maintaining its toxicity low. Our study suggests that in chronic treatments a large, single, daily dose will be less toxic than the same dose divided into several daily dosings.
General Summary and Conclusions (2020)

The principal question raised and examined in this research is what normative justification can be provided for economic, social and cultural human rights (ESC rights) guaranteed under international law and how can or should this justification impact the State obligations emerging from these rights. The specific research questions needed to be answered in this regard were whether and in what manner human dignity provides a viable normative justification for economic, social and cultural human rights guaranteed under international law, and what concrete legal obligations of the State party flow from these rights and how these obligations are reflected in the jurisprudence of international human rights monitoring bodies from across jurisdictions. This also implied the question concerning the kind of legal obligations the State bears towards the vulnerable persons within its jurisdiction. These questions are born out of the current limitations and lack of substantive progress in both the academic debate and practical enforcement of ESC rights. This study has accordingly examined in detail the nature, justification and scope of the State obligations flowing from ESC rights enshrined in international law.
The genes for secretion and maturation of lactococcins are located on the chromosome of Lactococcus lactis IL1403 (1996)

Southern hybridization and PCR analysis were used to show that Lactococcus lactis IL1403, a plasmid-free strain that does not produce bacteriocin, contains genes on its chromosome that are highly homologous to lcnC and lcnD and encode the lactococcin secretion and maturation system. The lcnC and lcnD homologs on the chromosome of IL1403 were interrupted independently by Campbell-type integrations. Both insertion mutants were unable to secrete active lactococcin. Part of the chromosomal lcnC gene was cloned and sequenced. Only a few nucleotide substitutions occurred, compared with the plasmid-encoded lcnC gene, and these did not lead to changes in the deduced amino acid sequence. No genes homologous to those for lactococcin A, B, or M could be detected in IL1403, and the strain does not produce bacteriocin activity.
Sleeping ECG and body position monitoring system (2009)

A textile-based ECG system for sleeper is presented. The electrode in the system is supported by a foam pad to ensure good contact as well as comfort to the wearer, and a flexible rubber to ensure that the electrode will electrically connect to the wearer only when pressed. Eight electrodes are multiplexed such that exactly two electrodes are pressed to connect the wearer no matter how the wearer lies. When the wearer lies in different positions, he/she will press different two electrodes, and then the morphology of the output ECG signal will be different accordingly. By this feature, the system can not only detect ECG but also determine the position of the sleeper.
Trading off Cache Capacity for Reliability to Enable Low Voltage Operation (2008)

One of the most effective techniques to reduce a processor’s power consumption is to reduce supply voltage. However, reducing voltage in the context of manufacturing-induced parameter variations cancause many types of memory circuits to fail. As a result, voltage scaling is limited by a minimum voltage, often called Vccmin, beyond which circuits may not operate reliably. Large memory structures (e.g., caches) typically set Vccmin for the whole processor. In this paper, we propose two architectural techniques that enable microprocessor caches (L1and L2), to operate at low voltages despite very high memory cell failure rates. The Word-disable scheme combines two consecutive cache lines, to form a single cache line where only non-failing words are used. The Bit-fix scheme uses a quarter of the ways in a cache set to store positions and fix bits for failing bits in other ways of the set. During high voltage operation, both schemes allow use of the entire cache. During low voltage operation, they sacrifice cache capacity by 50% and 25%, respectively, to reduce Vccmin below 500mV. Compared to current designs with a Vccmin of 825mV, our schemes enable a 40% voltage reduction, which reduces power by 85% and energy per instruction (EPI) by 53%
Remote sensing of ocean color: a methodology for dealing with broad spectral bands and significant out-of-band response (1995)

A methodology for delineating the influence of finite spectral bandwidths and significant out-of-band response of sensors for remote sensing of ocean color is developed and applied to the Sea-viewing Wide-Field-of-view Sensor (SeaWiFS). The basis of the method is the application of the sensor's spectral-response functions to the individual components of the top-of-the-atmosphere (TOA) radiance rather than the TOA radiance itself. For engineering purposes, this approach allows one to assess easily (and quantitatively) the potential of a particular sensor design for meeting the system-sensor plus algorithms-performance requirements. In the case of the SeaWiFS, two significant conclusions are reached. First, it is found that the out-of-band effects on the water-leaving radiance component of the TOA radiance are of the order of a few percent compared with a sensor with narrow spectral response. This implies that verification that the SeaWiFS system-sensor plus algorithms-meets the goal of providing the water-leaving radiance in the blue in clear ocean water to within 5% will require measurements of the water-leaving radiance over the entire visible spectrum as opposed to just narrow-band (10-20-nm) measurements in the blue. Second, it is found that the atmospheric correction of the SeaWiFS can be degraded by the influence of water-vapor absorption in the shoulders of the atmospheric-correction bands in the near infrared. This absorption causes an apparent spectral variation of the aerosol component between these two bands that will be uncharacteristic of the actual aerosol present, leading to an error in correction. This effect is dependent on the water-vapor content of the atmosphere. At typical water-vapor concentrations the error is larger for aerosols with a weak spectral variation in reflectance than for those that display a strong spectral variation. If the water-vapor content is known, a simple procedure is provided to remove the degradation of the atmospheric correction. Uncertainty in the water-vapor content will limit the accuracy of the SeaWiFS correction algorithm.
Computing Visibility on Terrains in External Memory (2007)

We describe a novel application of the distribution sweeping technique to computing visibility on terrains. Given an arbitrary viewpoint v, the basic problem we address is computing the visibility map or viewshed of v, which is the set of points in the terrain that are visible from v. We give the first I/O-efficient algorithm to compute the viewshed of v on a grid terrain in external memory. Our algorithm is based on Van Kreveld's O(n lg n) time algorithm for the same problem in internal memory. It uses O(sort(n)) I/Os, where sort(n) is the complexity of sorting n items of data in the I/O-model. We present an implementation and experimental evaluation of the algorithm. Our implementation clearly outperforms the previous (in-memory) algorithms and can compute visibility for terrains of up to 4 GB in a few hours on a low-cost machine.
Inhibition of Eukaryote Protein Kinases by Isoquinoline and Oxazine Alkaloids (1997)

The aporphine isoquinoline alkaloid apomorphine is a potent inhibitor of the catalytic subunit (cAK) of rat liver cyclic AMP-dependent protein kinase (PKA), myosin light chain kinase (MLCK), and Ca(2+)- and phospholipid-dependent protein kinase C (PKC) (IC50 values 1, 11, and 8 microM, respectively). However, a number of O-methylated analogues of apomorphine are inactive or poor inhibitors of cAK. The benzophenanthridine isoquinoline alkaloid sanguinarine is a potent inhibitor of cAK but is a relatively poor inhibitor of PKC (IC50 values 6 and 217 microM respectively). However a number of methylated analogues of sanguinarine are inactive as cAK inhibitors. The aporphine isoquinoline alkaloids (+)-boldine and bulbocapnine are non-competitive inhibitors of MLCK with respect to both peptide substrate and ATP. The inhibition of cAK, MLCK, and PKC by apomorphine and sanguinarine is competitive with respect to ATP as substrate. The oxazine alkaloids darrow red, nile blue A, and oxazine 170 are variously effective as inhibitors of cAK, MLCK, PKC, and CDPK (IC50 values 4-65 microM). Ca2+ binds to apomorphine and (+)-boldine which, together with nile blue A and oxazine 170, are potent inhibitors of calmodulin (CaM)-dependent MLCK (IC50 values 11, 12, 4, and 7 microM, respectively), and interact with dansyl-CaM.
Metabolism of parathyroid hormone by Kupffer cells: analysis by reverse-phase high-performance liquid chromatography (1982)

Parathyroid hormone (PTH) undergoes rapid proteolysis in the liver, which results in the appearance of multiple COOH-terminal fragments in plasma. Using reverse-phase high-performance liquid chromatographic (HPLC) techniques, we have shown that biologically active bovine PTH (bPTH) internally labeled with [3H]tyrosine is, like 125I-labeled bPTH, rapidly metabolized by isolated rat Kupffer cells in vitro to multiple COOH-terminal fragments that are chemically identical with those previously found in plasma after metabolism in vivo. Quantitation of specific carboxyl fragments in crude mixtures is achieved rapidly by direct HPLC analysis and is as precise as that achieved by Edman degradation. In addition, several different carboxyl fragments with identical NH2 termini were resolved, revealing a complexity not apparent in previous studies employing direct Edman degradation of such mixtures. Parallel studies with [[35S]Met]bPTH show the generation, by the Kupffer cells in vitro, of several labeled NH2-terminal fragments which undergo rapid further degradation in vitro. Thus, hepatic metabolism of PTH by Kupffer cells proceeds by an initial endopeptidase cleavage within the hormonal sequence in a manner compatible with the generation of biologically active NH2 fragments.
Semantics-Preserving Bag-of-Words Models and Applications (2010)

The Bag-of-Words (BoW) model is a promising image representation technique for image categorization and annotation tasks. One critical limitation of existing BoW models is that much semantic information is lost during the codebook generation process, an important step of BoW. This is because the codebook generated by BoW is often obtained via building the codebook simply by clustering visual features in Euclidian space. However, visual features related to the same semantics may not distribute in clusters in the Euclidian space, which is primarily due to the semantic gap between low-level features and high-level semantics. In this paper, we propose a novel scheme to learn optimized BoW models, which aims to map semantically related features to the same visual words. In particular, we consider the distance between semantically identical features as a measurement of the semantic gap, and attempt to learn an optimized codebook by minimizing this gap, aiming to achieve the minimal loss of the semantics. We refer to such kind of novel codebook as semantics-preserving codebook (SPC) and the corresponding model as the Semantics-Preserving Bag-of-Words (SPBoW) model. Extensive experiments on image annotation and object detection tasks with public testbeds from MIT's Labelme and PASCAL VOC challenge databases show that the proposed SPC learning scheme is effective for optimizing the codebook generation process, and the SPBoW model is able to greatly enhance the performance of the existing BoW model.
Modelling auditory attention (2017)

Sounds in everyday life seldom appear in isolation. Both humans and machines are constantly flooded with a cacophony of sounds that need to be sorted through and scoured for relevant information-a phenomenon referred to as the 'cocktail party problem'. A key component in parsing acoustic scenes is the role of attention, which mediates perception and behaviour by focusing both sensory and cognitive resources on pertinent information in the stimulus space. The current article provides a review of modelling studies of auditory attention. The review highlights how the term attention refers to a multitude of behavioural and cognitive processes that can shape sensory processing. Attention can be modulated by 'bottom-up' sensory-driven factors, as well as 'top-down' task-specific goals, expectations and learned schemas. Essentially, it acts as a selection process or processes that focus both sensory and cognitive resources on the most relevant events in the soundscape; with relevance being dictated by the stimulus itself (e.g. a loud explosion) or by a task at hand (e.g. listen to announcements in a busy airport). Recent computational models of auditory attention provide key insights into its role in facilitating perception in cluttered auditory scenes.This article is part of the themed issue 'Auditory and visual scene analysis'.
Immunohistochemical and Biochemical Characterization of Mucin in Pseudomyxoma Peritonei: A Case Study (2011)

We previously reported the presence of MUC2, MUC5AC and, for the first time, MUC5B in a 58-year-old male with pseudomyxoma peritonei (PMP). This is a report on the biochemical and immunohistochemical characterization of mucin in a 50-year-old female with the same rare illness. A right oophorectomy and appendicectomy and a resection of the involved omentum were performed. Approximately a litre of crude material in the sol and gel phases was obtained from the patient during laparotomy. This was briefly homogenized in 6 M guanidinium hydrochloride and proteolytic inhibitors and purified by density gradient centrifugation in caesium chloride. At laparotomy it was noted that the patient had appendiceal and ovarian masses as well as extensive mucinous deposits in the omentum and peritoneum. A mucinous adenocarcinoma of the appendix and ovary was confirmed on histology. The cells expressed both sulphated and non-sulphated acidic mucins. The presence of MUC2, MUC5AC, MUC5B and a-1-acid glycoprotein was shown by Western blotting and MUC4 by immunohistochemical staining. MUC1 and MUC6 were not detectable in the tissue. The study confirms that MUC2, MUC5AC and MUC5B are produced in the mucus of patients with PMP. The expression of MUC4 in this disease has not been previously reported.
Optical Absorption Engineering in Stacked Plasmonic Au–SiO<sub>2</sub>–Pd Nanoantennas (2012)

The nonradiative decay of a localized surface plasmon through absorption of a captured photon and excitation of an energetic electron-hole pair is a potentially very effective way to enhance chemical reactions on metal nanoparticle surfaces, so far limited to Ag (and Au). Here we explore the possibility of efficient and spectrally widely tunable optical absorption engineering based on heterometallic optical nanoantennas. They consist of an optimized antenna element made of Au (or Ag) and a catalytically active second metallic element separated by a thin SiO(2) layer. Specifically, we find that stacked Au-SiO(2)-Pd nanodisk antennas exhibit pronounced local absorption enhancement in the catalytic Pd particle. The effect is caused by efficient power transfer from the Au disk, exhibiting a narrow low-loss resonance and acting as an antenna collecting photons, to the Pd disk due to strong coupling between the two. The Pd element thus acts as receiver that efficiently dissipates energy into electron-hole pairs owing to efficient coupling to intra and interband transitions. In fact, the energy transfer is found to be so effective that the absorption efficiency at a given wavelength can be enhanced up to 6 to 9 times, and the total absorption integrated over a wide spectral range (400-900 nm) up to 2-fold, depending on the antenna dimensions. This finding suggests a novel route toward highly efficient plasmon-enhanced catalysis on widely selectable catalytic metal particle surfaces not limited to the "classic" plasmonic metals Au and Ag.
Lidocaine/<scp>l</scp>-Menthol Binary System: Cocrystallization versus Solid-State Immiscibility (2010)

We present the synthesis, structure determination, and thermodynamic properties of a never reported cocrystal prepared with lidocaine and L-menthol. The temperature-composition phase diagram of the lidocaine/L-menthol binary system was achieved using differential scanning calorimetry and X-ray diffraction experiments. The present study demonstrates that the only way to perform a phase equilibrium survey of the lidocaine/L-menthol system is to prepare the binary mixtures from the cocrystal, an equimolar stoichiometric compound of L-menthol and lidocaine. We describe a process that is crucial to elaborate pharmaceutical agents that remain in their thermodynamical stable state throughout their preparation, manufacture, and storage for effective use.