gebhart/patrepeval huggingface dataset:
Antimicrobial Peptides and Colitis (2012)

Antimicrobial peptides (AMPs) are important components of innate immunity. They are often expressed in response to colonic inflammation and infection. Over the last several years, the roles of several antimicrobial peptides have been explored. Gene expression of many AMPs (beta defensin HBD2-4 and cathelicidin) is induced in response to invasion of gut microbes into the mucosal barrier. Some AMPs are expressed in a constitutive manner (alpha defensin HD 5-6 and beta defensin HBD1), while others (defensin and bactericidal/ permeability increasing protein BPI) are particularly associated with Inflammatory Bowel Disease (IBD) due to altered defensin expression or development of autoantibodies against Bactericidal/permeability increasing protein (BPI). Various AMPs have different spectrum and strength of antimicrobial effects. Some may play important roles in modulating the colitis (cathelicidin) while others (lactoferrin, hepcidin) may represent biomarkers of disease activity. The use of AMPs for therapeutic purposes is still at an early stage of development. A few natural AMPs were shown to be able to modulate colitis when delivered intravenously or intracolonically (cathelicidin, elafin and SLPI) in mouse colitis models. New AMPs (synthetic or artificial non-human peptides) are being developed and may represent new therapeutic approaches against colitis. This review discusses the latest research developments in the AMP field with emphasis in innate immunity and pathophysiology of colitis.
An overview of Wireless Sensor Networks towards internet of things (2017)

With the advancements in wireless technology and digital electronics, some tiny devices have started to be used in numerous areas in daily life. These devices are capable of sensing, computation and communicating. They are generally composed of low power radios, several smart sensors and embedded CPUs (Central Processing Units). These devices are used to form wireless sensor network (WSN) which is necessary to provide sensing services and to monitor environmental conditions. In parallel to WSNs, the idea of internet of things (IoT) is developed where IoT can be defined as an interconnection between identifiable devices within the internet connection in sensing and monitoring processes. This paper presents detailed overview of WSNs. It also assesses the technology and characteristics of WSNs. Moreover, it provides a review of WSN applications and IoT applications.
Aberrant 3′ splice sites in human disease genes: mutation pattern, nucleotide structure and comparison of computational tools that predict their utilization (2006)

Despite a growing number of splicing mutations found in hereditary diseases, utilization of aberrant splice sites and their effects on gene expression remain challenging to predict. We compiled sequences of 346 aberrant 5'splice sites (5'ss) that were activated by mutations in 166 human disease genes. Mutations within the 5'ss consensus accounted for 254 cryptic 5'ss and mutations elsewhere activated 92 de novo 5'ss. Point mutations leading to cryptic 5'ss activation were most common in the first intron nucleotide, followed by the fifth nucleotide. Substitutions at position +5 were exclusively G>A transitions, which was largely attributable to high mutability rates of C/G>T/A. However, the frequency of point mutations at position +5 was significantly higher than that observed in the Human Gene Mutation Database, suggesting that alterations of this position are particularly prone to aberrant splicing, possibly due to a requirement for sequential interactions with U1 and U6 snRNAs. Cryptic 5'ss were best predicted by computational algorithms that accommodate nucleotide dependencies and not by weight-matrix models. Discrimination of intronic 5'ss from their authentic counterparts was less effective than for exonic sites, as the former were intrinsically stronger than the latter. Computational prediction of exonic de novo 5'ss was poor, suggesting that their activation critically depends on exonic splicing enhancers or silencers. The authentic counterparts of aberrant 5'ss were significantly weaker than the average human 5'ss. The development of an online database of aberrant 5'ss will be useful for studying basic mechanisms of splice-site selection, identifying splicing mutations and optimizing splice-site prediction algorithms.
Trial results of novel bit error rate monitor scheme over skywave HF link (1991)

Details are given of an error monitoring technique applicable to any digital communications system. An example application of the technique to a live skywave HF link using parallel-tone modems is described. The performance of the scheme is presented and discussed for this channel.
A photo-oxidation of croconic acid into oxalic acid (1995)

Croconic acid, H 2 C 5 O 5 , is readily oxidized. This may be attested by decolorization of the solutions and by observation of oxalic acid complexes. The oxidation products are identified by 13 C NMR spectroscopy as oxalic and mesoxalic acids, and experimental conditions are specified. The oxidation process requires dioxygen and photons. In parallel, the electrochemical oxidation of croconic acid is studied in aqueous media and in acetonitrile. A potential–pH diagram is drawn. Keywords: croconic acid, oxalic acid, oxidation, electrochemistry, photochemistry.
Aptamer-based electrochemical sensors that are not based on the target binding-induced conformational change of aptamers (2008)

This study describes a new kind of aptamer-based electrochemical sensor that is not based on the target binding-induced conformational change of the aptamers by using a 15-mer thrombin-binding aptamer (5'-GGTTGGTGTGGTTGG-3') as the model oligonucleotide. The sensors are developed by first self-assembling the aptamer (i.e. a thrombin-binding aptamer) onto an Au electrode and then hybridizing the assembled aptamer with a ferrocene (Fc)-labeled short aptamer-complementary DNA oligonucleotide to form an electroactive double-stranded DNA (ds-DNA) oligonucleotide onto the Au electrode. The binding of the target (i.e. thrombin) towards the aptamer essentially destroys the Watson-Crick helix structure of the ds-DNA oligonucleotide assembled onto the electrode and leads to the dissociation of the Fc-labeled short complementary DNA oligonucleotide from the electrode surface to the solution, resulting in a decrease in the current signal obtained at the electrode, which can be used for the determination of the target. With the thrombin-binding aptamer as the model oligonucleotide, the current decrease obtained with the aptamer-based electrochemical sensors is linear with the concentration of thrombin within the concentration range from 0 to 10 nM (DeltaI/nA = 6.7C(thrombin)/nM + 2.8, gamma = 0.975). Unlike most kinds of existing aptamer-based electrochemical sensor, the electrochemical aptasensors demonstrated here are not based on the conformational change of the aptamers induced by the specific target binding. Moreover, the aptasensors are essentially label-free and are very responsive toward the targets. This study may pave a facile and general way to the development of aptamer-based electrochemical sensors.
ChemInform Abstract: THE STEREOCHEMISTRY OF THE ADDITION OF DICHLOROSILANE TO ACETYLENES (1974)

Abstract Die Stereochemie der Addition von Dichlorsilan (I) an fünf substituierte Acetylene (II) wird untersucht.
[Significance of intraoperative precise management on intracavitary treatment for pulmonary thromboembolism]. (2016)

Thrombus fragmentation by pigtail catheter with intraoperativeprecise management under general anesthesia can reduce cardiac adverse events andimprove the mid-and-long-term effects among PE patients.
Fall Migration in Coastal Louisiana and the Evolution of Migration Patterns in the Gulf Region (1972)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Lactococcus nasutitermitis sp. nov. isolated from a termite gut (2015)

Bacterial strain M19T was isolated from the gut of a wood-feeding termite, Nasutitermes hainanensis. Phylogenetic analysis based on 16S rRNA gene sequences indicated that strain M19T was related to members of the genus Lactococcus, with sequence similarities ranging from 84.8 to 95.5 %. Comparison of housekeeping gene ropB sequences revealed that strain M19T was well separated from Lactococcus fujiensis JCM 16395T and Lactococcus hircilactis 117T. The isolate was Gram-stain-positive, catalase-negative and non-motile. Cells were coccoid or ovoid-shaped, and occurred singly, in pairs or as short chains. Growth of strain M19T occurred at 10-40 °C and at pH 5.0-7.5. The DNA G+C content of strain M19T was 39.6 mol% and the major fatty acids were C16 : 0, cyclo-C19 : 0ω8c, C18 : 1ω9c, summed feature 7 and summed feature 8. Based on the phylogenetic, chemotaxonomic and phenotypic data presented, strain M19T represents a novel species of the genus Lactococcus, for which the name Lactococcus nasutitermitis sp. nov. is proposed. The type strain is M19T ( = CGMCC 1.15204T = NBRC 111537T).
On-Chip Ultra-Small Arbitrary-Elliptical-Polarization Converters (2021)

On-chip arbitrary-elliptical-polarization converter plays a key role in optical information processing. However, the traditional method of manually adjusting parameters for designing devices is limited in function. In this letter, on-chip ultra-small arbitrary-elliptical-polarization converters are realized through optimization algorithms based on genetic algorithm (GA) combined with finite element method (FEM). The converters can realize the function of arbitrary ellipticity angle conversion of full polarization states. The size of the core device is only 1 μm × 1 μm, which is very conducive to high-density integration. The difference between the ideal output ellipticity angle and the actual output ellipticity angle of each device is no more than 2 degrees. In addition, it is proved that the use of optimization algorithms can easily design arbitrary-elliptical-polarization converters with different materials, different structures and different wavelengths, and the design of three-dimensional arbitrary-elliptical-polarization converters is also verified by using the optimization algorithm. This work provides an efficient design method for arbitrary polarization state conversion, showing its significance in improving the information capacity in optical communication.
Automated morphological analysis of cells in body fluids by the digital microscopy system DM96 (2010)

The DM96 has proven to be reliable and efficient, contributing to overall quality improvement in morphological analysis and automated cell classification of peripheral blood and other body-fluid samples.
Some hydroxyamidines and amidoximes (1976)

A number of hydroxyamidines and amidoximes have been prepared in order to examine if their chelating system can lead to cytotoxic compounds. Most compounds are toxic but all are inactive against experimental tumours. The i.r., u.v. and N.M.R. spectra of the hydroxyamidines are discussed.
Haptic Illusions: Experiments on Human Manipulation and Perception of "Virtual Objects" (1990)

The use of tools is one of the distinctive features of human behavior. Although other species make and use rudimentary tools, this behavior is most highly developed in humans. What is the nature of the underlying neural processes? What does the brain have to do to accomplish effective tool use?
Precision measurement of the refractive index of air with frequency combs (2005)

We report an experimental method for high-precision refractive index measurement using a Michelson interferometer setup with a femtosecond optical frequency comb as the light source. We demonstrate this technique by measuring the refractive index of air, under different pressures, inside a 29 m multipass cell. Both spectral and temporal interferograms are recorded. The method has a sensitivity of 6.2 x 10(-9) and a standard error of 7.4 x 10(-8) at fixed parameters (pressure and temperature). The possible variation of the density factor from the Lorentz-Lorenz equation is also discussed.
Identification and characterization of T helper cell epitopes of the major outer membrane protein of Chlamydia trachomatis. (1990)

Chlamydia trachomatis serovars A, B, and C are the causative agents of trachoma, the world's leading cause of preventable blindness. Immunoprophylaxis is a possible approach to control trachoma. The chlamydial major outer membrane protein (MOMP) is thought to play an important role in the development of protective immunity against chlamydial infection, and is therefore considered to be a promising candidate antigen in the development of a trachoma vaccine. Much effort has been focused on the molecular characterization of B cell sites of the MOMP that elicit neutralizing antibodies. Neutralizing sites have been identified as linear epitopes that reside within variable domains (VDs) of the protein whose primary sequences vary among different serovars. No information exists on MOMP T helper (Th) cell antigenic determinants, which are likely critical components for the development of a successful chlamydial vaccine. We used overlapping synthetic peptides (25 mers) representing the entire primary sequence of serovar A MOMP in T cell proliferation assays to identify T cell antigenic determinants of this molecule. Eight synthetic peptides (A-2, A-3, A-7, A-8, A-11, A-22, A-23, and A-24) stimulated proliferative responses of splenic T cells isolated from MOMP-immunized A/J mice. To ascertain if these peptides functioned as Th cell antigens, we determined their ability to prime A/J mice in vivo to produce an anamnestic IgG response specific to the MOMP. Mice primed with synthetic peptides A-8 (106-130) or A-23 (331-355) produced IgG antibodies reactive with the native MOMP and with the synthetic peptides corresponding to surface-accessible serovar-specific epitopes located in VD I and serogroup-specific epitopes located in VD IV of the protein. We synthesized the A-8 and A-23 peptides with the VD I sequence as colinear chimeric peptides. Immunization of mice with the T/B cell peptides produced high titered antibodies against the VD I sequence, and these antibodies reacted with the native MOMP and intact chlamydiae. The MOMP sequences containing these Th cell epitopes are conserved among the MOMP genes of different C. trachomatis serovars, indicating that they are common Th cell antigenic sites. Thus, the Th cell epitopes contained within these peptides, in combination with different trachoma serovar-specific B cell neutralizing determinants, may be useful in the development of a synthetic or recombinant trivalent trachoma vaccine.
Effective clustering of objects stored by linear hashing (1995)

Article Free Access Share on Effective clustering of objects stored by linear hashing Author: Jukka Teuhola Dept. of Computer Science, Univ. of Turku, Lemminkäisenkatu 14, FIN-20520 Turku, Finland Dept. of Computer Science, Univ. of Turku, Lemminkäisenkatu 14, FIN-20520 Turku, FinlandView Profile Authors Info & Claims CIKM '95: Proceedings of the fourth international conference on Information and knowledge managementDecember 1995 Pages 274–280https://doi.org/10.1145/221270.221590Published:02 December 1995Publication History 0citation299DownloadsMetricsTotal Citations0Total Downloads299Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Manchuria Expanding Cotton Textile Industry (1937)

Other| February 03 1937 Manchuria Expanding Cotton Textile Industry J. R. S. J. R. S. Search for other works by this author on: This Site PubMed Google Scholar Far Eastern Survey (1937) 6 (3): 35–36. https://doi.org/10.2307/3021934 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation J. R. S.; Manchuria Expanding Cotton Textile Industry. Far Eastern Survey 3 February 1937; 6 (3): 35–36. doi: https://doi.org/10.2307/3021934 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAsian Survey Search This content is only available via PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Early Kick Detection Using Real Time Data Analysis with Dynamic Neural Network: A Case Study in Iranian Oil Fields (2010)

Abstract One of the important challenges in drilling a well is kick detection. In fact, ignoring the signs of a kick lead us to complicated problems in killing the well and consequently, if the kick could not be controlled a blowout may occur. Therefore, considering the early detective parameters seems crucial. Kick happens because some parameters like tank volumes are changed when the time passes, so static neural network cannot predict this occurrence; therefore, using dynamic neural network, which incorporate the previous data could predict the system manner better than the static one. In this paper, a dynamic neural network model is presented and good results with acceptable accuracy are shown. The model was trained with some Iranian onshore oil wells that kick was encountered in them. The kicks were predicted longer before it could have been detected by the drilling crew.
Peripheral metabolic actions of leptin (1998)

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
New Insecticidal Rocaglamide Derivatives from the Roots of <i>Aglaia </i><i>d</i><i>uperreana</i> (1999)

Bioassay-guided fractionation of an extract obtained from roots of Aglaia duperreana led to the isolation of 17 1H-cyclopenta[b]benzofurans of the rocaglamide type. Of the compounds isolated, four rocaglamide derivatives (2, 6, 11, and 16) were obtained as new natural products, and their structure elucidation was conducted by spectral methods. For bioassay-guided fractionation and determination of LC50 and EC50 values, neonate larvae of Spodoptera littoralis were employed. The results of chronic feeding assays have shown new aspects of the structure−activity relationship of rocaglamide derivatives. The substitution of a hydroxyl group at C-8b by a methoxyl substituent leads to a loss of insecticidal activity in a manner not previously documented in this compound class.
Location recommendation for out-of-town users in location-based social networks (2013)

Most previous research on location recommendation services in location-based social networks (LBSNs) makes recommendations without considering where the targeted user is currently located. Such services may recommend a place near her hometown even if the user is traveling out of town. In this paper, we study the issues in making location recommendations for out-of-town users by taking into account user preference, social influence and geographical proximity. Accordingly, we propose a collaborative recommendation framework, called User Preference, Proximity and Social-Based Collaborative Filtering} (UPS-CF), to make location recommendation for mobile users in LBSNs. We validate our ideas by comprehensive experiments using real datasets collected from Foursquare and Gowalla. By comparing baseline algorithms and conventional collaborative filtering approach (and its variants), we show that UPS-CF exhibits the best performance. Additionally, we find that preference derived from similar users is important for in-town users while social influence becomes more important for out-of-town users.
Practical Wide-Sense Nonblocking Generalized Connectors (1988)

In this note, we show that wide-sense nonblocking networks can be obtained by cascading a pair of Cantor networks or a pair of Clos networks. The only constraint placed on the routing algorithms is that branching be restricted to the second network in the cascade. This result yields practical network for multipoint communication with complexities O(N(logN)2 and O(N1+1/r).
Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis. (1995)

To examine whether mtDNA is uni- or biparentally transmitted in mice, we developed an assay that can detect sperm mtDNA in a single mouse embryo. In intraspecific hybrids of Mus musculus, paternal mtDNA was detected only through the early pronucleus stage, and its disappearance co-incided with loss of membrane potential in sperm-derived mitochondria. By contrast, in interspecific hybrids between M. musculus and Mus spretus, paternal mtDNA was detected throughout development from pronucleus stage to neonates. We propose that oocyte cytoplasm has a species-specific mechanism that recognizes and eliminates sperm mitochondria and mtDNA. This mechanism must recognize nuclearly encoded proteins in the sperm midpiece, and not the mtDNA or the proteins it encodes, because sperm mitochondria from the congenic strain B6.mtspr, which carries M. spretus mtDNA on background of M. musculus (B6) nuclear genes, were eliminated early by B6 oocytes as in intraspecific crosses. We conclude that cytoplasmic genomes are transmitted uniparentally in intraspecific crosses in mammals as in Chlamydomonas and that leakage of parental mtDNA is limited to interspecific crosses, which rarely occur in nature.
How Much Oxygen Does the Human Lung Consume? (1997)

The lung consumes about 5% of whole-body oxygen uptake.
Content based selection of capture resolution in smartphone camera (2015)

Smartphone camera resolution is increasing fast to meet the user expectation. With the increase in resolution the need of storage capacity as well as power consumption in processing the images is increasing. Though a user can set the resolution of an image before capture, most of the time the user does not change the pre-selected resolution for capturing multiple images. If the pre-selected resolution is maximum, the user may consume too much storage and if the preselected resolution is minimum the user may lose significant information for some images. Thus a fixed resolution is not recommended for all the images. In this work we propose a method of automatically suggesting an optimum capture resolution based on the content of the preview image, and works in real time. The proposed method enables the user to capture an image with varying resolution depending on the quality of the preview. This method may be useful in saving a significant memory space in storing captured images as well as power consumption without loss of quality of the image.
Taxonomie studies on streptomycetes causing potato common scab: a review (1996)

(1996). Taxonomie studies on streptomycetes causing potato common scab: a review. Canadian Journal of Plant Pathology: Vol. 18, No. 2, pp. 107-113.