gebhart/patrepeval huggingface dataset:
Recognition of Porphyromonas gingivalis Gingipain Epitopes by Natural IgM Binding to Malondialdehyde Modified Low-Density Lipoprotein (2012)

Gingipain of P. gingivalis is recognized by natural IgM and shares molecular identity with epitopes on MDA-LDL. These findings suggest a role for natural antibodies in the pathogenesis of two related inflammatory diseases, atherosclerosis and periodontitis.
The present and the future of random signal radars (1997)

The 30+ year development of random signal radar (RSR) is described in this paper. Conventional methods of implementing RSRs are summarized: correlation, spectrum analysis, and anti-correlation. Some typical RSR systems are introduced; for example: noise frequency modulation continuous wave radar; and random binary phase-coded continuous wave radar, and their merits and demerits are also pointed out. Finally, the development trends of RSR is analyzed.
Interlinking Music-Related Data on the Web (2009)

This article describes how semantic Web technologies can be used to interlink musical data sources that have traditionally been isolated and difficult to integrate.
The Failure of Thin Alluminum Current-Carrying Strips on Oxidized Silicon (1966)

A new mode of metal failures is described - electrical opens in Al strips on SiO2 - resulting from the passage of direct current at high current density. The lifetime of aluminum strips was found to depend not only on the magnitude of the applied current, but also on its direction. At lower current levels (longer lifetimes), a much longer lifetime was seen when alternating current was employed (60 cycles/sec) than for direct current. This effect, toether with the fact that aluminum films carrying direct currents have a blistered appearance suggests that an electrochemical or electromigration mechanism is involved in the disruption of the aluminum strips. While opens are very rarely seen at "normal" current densities of 105 a/cm2, the failure mode is accelerated at high current densities (106 a/cm2) and elevated temperatures (200°c). The distruption of the aluminum films does not originate from diffusion of the aluminum into silicon (emitted or base region) or addition, the gold ball bonds can act as sinks for the thin aluminum films surrounding them, and, hence, cause a certain enhancement of failures.
Pain Tolerance: Differences According to Age, Sex and Race (1972)

The nature and extent of group differences in pain tolerance according to age, sex and race were examined. The method of pain tolerance determination was mechanical pressure on the Achilles tendon, performed on 41, 119 subjects as part of the Kaiser-Permanente Automated Multiphasic Screening examination. The results showed that, on the average, a) pain tolerance decreases with age; b) men tolerate more pain than women; and c) Whites tolerate more pain than Orientals, while Blacks occupy an intermediate position. When the results of this study are compared with earlier work, it appears that, with increasing age, tolerance to cutaneous pain increases and tolerance to deep pain decreases.
Identification of quaternary alkaloids in mushroom by chromatography/secondary ion mass spectrometry (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of quaternary alkaloids in mushroom by chromatography/secondary ion mass spectrometryS. E. Unger, Adam. Vincze, R. G. Cooks, Ray. Chrisman, and L. D. RothmanCite this: Anal. Chem. 1981, 53, 7, 976–981Publication Date (Print):June 1, 1981Publication History Published online1 May 2002Published inissue 1 June 1981https://pubs.acs.org/doi/10.1021/ac00230a012https://doi.org/10.1021/ac00230a012research-articleACS PublicationsRequest reuse permissionsArticle Views244Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A METHOD OF STIMULATING THE COMPLETE SYMPATHETIC OUTFLOW FROM THE SPINAL CORD TO BLOOD VESSELS IN THE PITHED RAT (1967)

The effects of sympathetic nerve stimulation on blood vessels have been studied in a variety of ways. The vascular beds of various organs or regions have been perfused either in vivo or in vitro with blood or saline and the pressor response to stimulation of the operatively exposed sympathetic nerves measured. In other experiments the response of isolated arteries to stimulation of their sympathetic nerves has been studied. None of these methods gives information on the integrated response of the blood vessels constituting the peripheral resistance to stimulation of the entire sympathetic outflow. Furthermore, in experiments stimulating exposed sympathetic nerves, the operative interference in making the preparation may itself affect the vascular responses.
Chemical Genetics–Based Target Identification in Drug Discovery (2011)

Identification of novel, validated targets remains a top priority in modern drug discovery. Chemical genetics represents a powerful approach to the discovery of new targets. Unlike the traditional target-based screen that relies on a predefined, sometimes poorly validated target, a chemical genetics-based phenotypic screen probes the entire molecular signaling pathway in an efficient and unbiased manner for the most drug-sensitive node. The most significant obstacle associated with this approach is identification of the efficacy targets of small-molecule probes. The huge potential of chemical genetics cannot be realized without the establishment of reliable mechanisms for target identification. In this article, we describe each essential element of the chemical genetics process, discuss common challenges that the field is facing, and critically review various biochemical and genetics approaches recently developed for target deconvolution. We also attempt to summarize lessons that we have collectively learned and provide a practical perspective to facilitate the advancement of chemical genetics.
<title>Protecting identity documents with a just-noticeable microstructure</title> (2002)

The development of plastic card printers has led to the widespread use of identity documents printed on plastic cards, such as ID cards, driving licenses and access key cards. This paper presents a new security feature based on a technique for embedding a personalized microstructure into a photograph. This microstructure takes the form of a bitmap pattern embedded into the original photograph as a succession of balanced chromatic shifts. The amplitude of these shifts may be modulated so as to make the pattern fully apparent, just noticeable, or completely invisible under normal viewing conditions. Since the chromatic shifts cancel each other out in any macroscopic portion of the image, the global appearance of the protected image remains intact. The embedded microstructure may be adapted to each instance of the protected identity document. For example, it can repeat textual information already present elsewhere on the document, or it can include a code derived from data specific to the document holder. Furthermore, this information may be made fully readable without the help of a specialized apparatus. Such identity documents exhibit an intrinsic resistance against imitation, tampering and substitution
Non‐Uniform Infiltration Under Potato Canopies Caused by Interception, Stemflow, and Hilling<sup>1</sup> (1976)

Abstract It is generally assumed that infiltration of sprinkler irrigation and rainfall under potato is uniform. However we observed non‐uniform infiltration beneath the hills of sprinkler‐irrigated potatoes ( Solanum tuberosum L, var. Russet Burbank) grown on Plainfield loamy sand (Typic Udipsamment; sandy, mixed, mesic). The objective of this field study was to determine the effects of foliage interception and hilling on non‐uniform infiltration, since concentrating water in local zones would increase deep drainage and nitrogen leaching. To do this we traced the rainfall and irrigation infiltration pattern with Rhodamine WT dye and collected the stemflow in stem collars. Throughfall of rainfall, the soil water content, and soil water tension also were measured. From 20 to 46% of the irrigation and from 4 to 23% of the rainfall on the canopy flowed down the stems. Stemflow increased the soil water content around the stems and moved Rhodamine dye deep beneath the soil surface. Deep movement of dye beneath the furrows was caused by runoff from the hills and by leaf drip from the outer foliage. The results obtained suggest that irrigation and fertilizer management could be improved by taking this non‐uniform infiltration pattern into account. Smaller irrigations should improve water use efficiency and minimize nitrate leaching. Further, evaluation of solute movement by soil sampling should consider the spatial variation introduced by the non‐uniform infiltration. Finally, predictive leaching models should account for non‐uniform infiltration.
Study of a Solar Booster Assisted Ejector Refrigeration System With R134a (2005)

The studies of ejector refrigeration systems employing refrigerant R134a for air conditioning are scarce and nonexistent for ice making when its potential application in developing countries will lessen their refrigeration needs. So, a parametric study for an ice making solar booster assisted ejector refrigeration system operating with R134a is carried out. System energy and exergy efficiencies as well as ejector efficiency are presented as a function of generator and condenser temperatures and booster discharge pressure. A discussion on maximum ejector efficiency and its effect in system behavior is also carried out. With results indicating that for an evaporator temperature of −10°C, the system can operate at a generator temperature of 85°C with average energy efficiencies between 0.21 and 0.58, depending on the condenser temperature. Consequently, these systems could be a solution for solar refrigeration using off-the-shelf components.
Polymorphic FIR Filters with Backup Mode Enabling Power Savings (2009)

A polymorphic FIR filter is proposed which can operate in two modes. The first mode is considered as a standard mode in which the filter performs a normal operation. In the second mode, the filter operates with reduced power supply voltage (Vdd), some filter coefficients are reconfigured (as response to the change of the polymorphic gates function which is controlled by Vdd) and some parts of the filter are disconnected. Experimental results indicate that while power consumption can significantly be reduced when half of the taps is suspended the filter is still able to achieve a reasonable quality of filtering.
Design considerations and performance of a spectro-streak apparatus applying a planar LIGA microspectrometer for time-resolved ultrafast fluorescence spectroscopy (1996)

Results of a pilot study with a spectro-streak apparatus applying a grating microspectrometer with a self-focusing reflection grating are reported. The microspectrometer chip (dimensions: 17×6.4 mm2; 125 μm effective thickness of the three-layer x-ray resist system), fabricated with the versatile LIGA technique, has been adapted to a picosecond streak camera. Performance tests have been carried out with a fluorescent probe exhibiting a dynamic Stokes shift of the exciplex fluorescence band due to solvation of the charge transfer dipole within about 400 ps. The use of a LIGA microspectrometer in ultrafast spectroscopy proved to be of advantage in time-resolved studies of complex luminescence spectra where a moderate spectral resolution is required and a large spectral range must be covered.
TIRE CHIPS: A NEW ROAD-BUILDING GEOMATERIAL (1996)

Highway construction has the potential to make a significant contribution to disposal of the 2 billion to 3 billion scrap tires that are stored or discarded throughout the United States. A recently constructed tire-chip fill in Maine, which was 120 m (400 ft) long, used 200,000 tires. The in-place density of tire chips is less than 50% of that for a typical gravel fill, making them an ideal lightweight fill to stabilize embankments against landslides. In Maine tire chips are being used to construct a bridge-approach fill that is 4.3 m (14 ft) thick to correct stability problems caused by a weak clay foundation. Concerning the effect of a compressible tire-chip layer on pavement life, for two projects in Maine, it was found that placing 1.8 m (6 ft) of soil cover over 0.61 m (2 ft) of maximum-size tire chips yielded tensile strains at the bottom of the test pavement that were the same as for a control section with no tire chips. Even for soil covers as shallow as 0.76 m (2.5 ft), the tensile strains at the bottom of the pavement were only 40% greater than those in the control section. The low unit weight and high permeability of tire chips makes them an attractive retaining-wall backfill. A test wall constructed at the University of Maine showed that the lateral earth pressure at the base of tire-chip fill 4.3 m (14 ft) thick with a 36-kPa (750-psf) surcharge was less than 50% of that for a typical gravel fill. Lower pressures would allow thinner, lower-cost walls to be constructed. These low earth pressures could result in significant cost savings for retaining walls and bridge abutments. Tire chips are also a good thermal insulator to limit frost penetration beneath roads. Their thermal resistance is approximately eight times higher than that of gravel. A test project constructed on a gravel-surfaced road in Maine showed that 0.3 m (1 ft) of tire chips reduced the depth of frost penetration by 40%. Finally, tire chips are inexpensive compared with natural fill materials. Tire chips can typically be purchased for between $2 and $13 per cu m ($1.50 to $10 per cu yd). (Edited Article)
Impact of contact evolution on the shelf life of organic solar cells (2009)

For organic photovoltaics (OPVs) to become a truly viable technology, it is critical to correctly identify their degradation mechanism(s) and pave the way for strategies to improve device lifetime. Changes in the active organic component are often cited as the leading degradation pathway in OPVs. In this shelf life study, we monitor device performance after storage in the dark at ambient conditions to show that decay behavior is dominated by changes at the top metal electrode and/or the metal–organic interface. Cross-sectional TEM reveals extensive void formation to be the primary degradation mechanism for Ca/Al contacts. Kelvin probe measurements show the work function of Ag contacts increases over time, consistent with silver oxide formation detected by TOF-SIMS depth profiles. The evolution of the work function is found to be advantageous for Ag as a hole-extracting contact, but unsuitable for electron-extraction. The combination of Ag positive contacts (to collect holes) and ITO/ZnO negative contacts (to collect electrons) yields devices that are stable up to one year when stored in ambient conditions.
Field demonstration of a Mars navigation system utilizing GPS pseudolite transceivers (2003)

Tasks envisioned for future generation Mars rovers-sample collection, area survey, resource mining, habitat construction, etc.-will require enhanced navigational capabilities over the Mars Sojourner rover. Many of these tasks will involve cooperative efforts by multiple rovers and other agents, adding further requirements both for accuracy and commonality between users. This paper presents a new navigation system (a self-calibrating pseudolite array) that can provide centimeter-level, drift-free localization to multiple rovers within a local area by utilizing GPS-based transceivers deployed in a ground-based array. Such a system of localized beacons can replace or augment a system based on orbiting satellite transmitters, and is capable of fully autonomous operations and calibration. This paper describes the prototype SCPA that has been developed at Stanford to demonstrate these capabilities and then presents new results from the most recent set of field trials performed at NASA Ames Research Center. These experiments, which utilize the K9 Mars rover research platform, validate both the navigation and self-calibration capabilities of the system.
Digital complex sampling (1983)

Complex sampling is often employed in digital signal processing schemes where the input signal is bandpass in origin and is to be processed using lowpass techniques. Conventionally the signal is first mixed to zero centre frequency in two quadrature channels, filtered to remove the high-frequency mixing products and then digitised in two A/D convertors. A method is proposed that employs only one A/D convertor followed by digital mixing to produce the required pair of signals, thus allowing a considerable saving in hardware.
Active Database Architectures and the Design of Sentinel for Constraint Management (1993)

Over the last few years active databases have become an important research area geared towards meeting of the requirements of a variety of non- traditional applications. This report concentrates on providing a seamless incorporation of events and rules into an OODBMS with an emphasis on the modularity and extensibility of the resulting system. The report extends the monitoring view point to an external one, thereby allowing objects to monitor and react to changes occurring to their own state as well as changes occurring to other objects. This is accomplished by introducing a reactive asynchronous object interface. This interface enables objects to propagate pre-declared events occurring to their state to other objects, thereby enabling other objects to perform operations. In addition, a subscription and notification mechanism is introduced that allows event notification to be specified dynamically. This mechanism enables objects to selectively monitor other objects at run-time using the reactive interface. A design is proposed for the specification and detection of simple as well as complex events. This report combines the strengths of the approaches taken in Ode and ADAM and extends them in several significant ways.
Parameters for the molecular recognition of transfer RNAs (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTParameters for the molecular recognition of transfer RNAsPaul SchimmelCite this: Biochemistry 1989, 28, 7, 2747–2759Publication Date (Print):April 4, 1989Publication History Published online1 May 2002Published inissue 4 April 1989https://pubs.acs.org/doi/10.1021/bi00433a001https://doi.org/10.1021/bi00433a001research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations74LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Baccalaureate Entry Into Practice: An Example of Political Innovation and Diffusion (1990)

ABSTRACT Activity within several states over the past two decades to require a baccalaureate nursing degree as the minimum educational preparation for licensure as a registered professional nurse is reviewed as an example of policy innovation and diffusion. Sufficient ratio of baccalaureate degree to associate degree programs and political party turnover in the governor's office have frequently accompanied private and public policy action on BS entry.
Sexual dimorphism among bovine embryos in their ability to make the transition to expanded blastocyst and in the expression of the signaling molecule IFN-τ (2001)

IFN-tau is a secretory product of trophectoderm of cattle, sheep, and their relatives and is expressed for a few days in early pregnancy after the blastocyst first forms. It serves to alert the mother that she is pregnant. A delayed or less than robust IFN-tau signal is a likely cause of embryonic loss. Here we have determined whether blastocyst production of IFN-tau, which is encoded by a cluster of genes on chromosome 9, differs between the sexes in cattle, as assessed by culture of in vitro-derived embryos on two different media, one complex (tissue culture medium 199 supplemented with serum) with coculture support, the other relatively simple (synthetic oviductal fluid plus albumin). With both media, female blastocysts produced approximately double the amount of IFN-tau as males, regardless of such variables as oocyte batch, blastocyst quality, hatching, and length of time in culture. However, in either tissue culture medium 199, which contains 5.5 mM d-glucose, or in synthetic oviductal fluid, in the presence but not in the absence of added glucose, significantly fewer female than male embryos were able to progress from the morula/early blastocyst stage to more advanced stages of development. It is possible that the differences between male and female embryos both in their production of IFN-tau and in their ability to progress in development in glucose-rich media are manifestations of phenomena that occur in vivo and provide plasticity in embryo selection during early pregnancy.
Toluene degradation by Pseudomonas putida F1: genetic organization of the tod operon (1988)

Pseudomonas putida PpF1 degrades toluene through cis-toluene dihydrodiol to 3-methylcatechol. The latter compound is metabolized through the well-established meta pathway for catechol degradation. The first four steps in the pathway involve the sequential action of toluene dioxygenase (todABC1C2), cis-toluene dihydrodiol dehydrogenase (todD), 3-methylcatechol 2,3-dioxygenase (todE), and 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase (todF). The genes for these enzymes form part of the tod operon which is responsible for the degradation of toluene by this organism. A combination of transposon mutagenesis of the PpF1 chromosome, as well as analysis of cloned chromosomal fragments, was used to determine the physical order of the genes in the tod operon. The genes were determined to be transcribed in the order todF, todC1, todC2, todB, todA, todD, todE.