gebhart/patrepeval huggingface dataset:
Degradable on-chip safety controller with intra-chip communication for steer-by-wire systems (2012)

High reliability and high availability are essential aspects for all critical elements used in automotive applications. This is particularly true for control and steering systems. In this regard, numerous steer by wire (x-by-wire) concepts were developed over the years. Most of them considered only standard single microcontroller system architectures with a low degree of reliability according to international reliability and safety standards. This paper presents a novel concept for a degradable safety controller for steer-by-wire systems. Based on a safety-related 1004-architecture, the presented concept offers higher safety, reliability and availability.
Development of an intranet security infrastructure and its application (2002)

As the support for X.509 digital certificate standardized in most Web browsers and servers, public-key cryptography is emerging as the security solution for both Internet and intranet applications. The paper describes the security infrastructure and solutions implemented for supporting AT&T long-distance network maintenance. This public-key infrastructure implements the short-lived certificate framework to reduce the cost associated with public-key management. The infrastructure supports a certification group concept that allows individual operation units within an organization to tailor their certification policies. This solution minimizes the changes needed for migrating existing applications to the SSI authentication framework.
Transmethylation and transguanylylation in 5'-RNA capping system isolated from rat liver nuclei. (1979)

Rat liver nuclei were isolated and sonicated for extraction in order to study the capping of RNA. The guanosine 7-methyltransferase was purified from the extract by hydroxylapatite column chromatography with stepwise addition of phosphate buffer. It was assayed by using as methyl acceptor synthetic G(5')ppp(5')G and S-adenosylmethionine as donor. The enzyme appeared in a sharp peak at 160 mM. The same peak fraction was subsequently found to contain the enzyme that guanylylates short synthetic polynucleotides and low molecular weight yeast RNA as acceptors. The two enzymatic activities were separated on Sephadex G-150 chromatography, yielding guanylyltransferase and guanosine 7-methyltransferase with molecular weights of approximately 65,000 and 130,000 respectively. Guanylyltransferase was further purified by CM-Sephadex chromatography, whereby G-7-methyltransferase was completely removed. Dithiothreitol was essential for guanylylation, and 2 mM Mn2+ (optimum) was twice as active as 8 mM Mg2+ (optimum). The alpha-32P of [32P]GTP, but not its beta- or gamma-32P was incorporated into the cap structure. By using unlabeled GTP with [beta-32P]ppGpCpC-poly(A2,U2,G) as acceptor, [beta'-32P]-GpppG... was formed. Our purified transguanylylation enzyme was found to catalyze a [32P]pyrophosphate exchange with GTP, which may be useful as a rapid assay for transguanylylation.
Constituency to Dependency Translation with Forests (2010)

Tree-to-string systems (and their forest-based extensions) have gained steady pop-ularity thanks to their simplicity and effi-ciency, but there is a major limitation: they are unable to guarantee the grammatical-ity of the output, which is explicitly mod-eled in string-to-tree systems via target-side syntax. We thus propose to com-bine the advantages of both, and present a novel constituency-to-dependency trans-lation model, which uses constituency forests on the source side to direct the translation, and dependency trees on the target side (as a language model) to en-sure grammaticality. Medium-scale exper-iments show an absolute and statistically significant improvement of +0.7 BLEU points over a state-of-the-art forest-based tree-to-string system even with fewer rules. This is also the first time that a tree-to-tree model can surpass tree-to-string counterparts. 1
Distributed fiber optics for temperature sensing in buildings and other structures (2002)

An optimized facility management and the risk assessment of buildings need a permanent up-dating of relevant data. Temperature is a key parameter to design and control air-conditioning installations; time and space variations of the temperature indicate damage situations in an early stage so that measures can be taken for damage prevention, for warning and for controlling escape routes in buildings. The fiber optic temperature sensing technique opens new possibilities and chances for permanent surveying of buildings, power supply installations, communication and data transmission systems.
An Improved FEC Scheme for 10G EPON Based on Channel Adaptation (2012)

To improve system capacity for 10G EPON, a channel-adaptive FEC scheme is proposed, which efficiently improves capacity performance by adopting the optimal code of each ONU and can be implemented with very low increment of complexity.
Generation of human cytotoxic T lymphocytes against fresh autologous and allogeneic solid tumors by mixed lymphocyte tumor cell culture with T cell growth factor. (1984)

Autologous mixed lymphocyte tumor cell culture (MLTC) induced cytotoxic lymphocytes against autologous tumor cells in 4 out of 14 donors (29%). Further cultivation of MLTC-activated lymphocytes with T cell growth factor (TCGF) resulted not only in the propagation of cytotoxic T lymphocytes (CTL) and an increase of cytotoxicity against autologous tumors, but also in the induction of killer cells against allogeneic tumor cells. Briefly, the results of crisscross tests using fresh tumor cells from 17 donors and lymphocytes from 10 donors indicate that cultivation of MLTC-activated lymphocytes with TCGF generated killer cells against allogeneic tumor cells in most cases, but not against autologous or allogeneic phytohemagglutinin-induced lymphoblasts. These effector cells were mainly OKT3+, OKT8+, OKM1- and Leu7-. Further, the results of cold target inhibition tests undertaken in an autologous tumor killing system suggest that at least 2 different subsets, specifically cytotoxic for autologous tumors and cytotoxic for both autologous and allogeneic tumors, were developed in the CTL induced by autologous MLTC followed by cultivation with TCGF.
A Novel Intensive Distribution Logistics Network Design and Profit Allocation Problem considering Sharing Economy (2018)

The rapid growth of logistics distribution highlights the problems including the imperfect infrastructure of logistics distribution network, the serious shortage of distribution capacity of each individual enterprise, and the high cost of distribution in China. While the development of sharing economy makes it possible to achieve the integration of whole social logistic resources, big data technology can grasp customer’s logistics demand accurately on the basis of analyzing the customer’s logistics distribution preference, which contributes to the integration and optimization of the whole logistics resources. This paper proposes a kind of intensive distribution logistics network considering sharing economy, which assumes that all the social logistics suppliers build a strategic alliance, and individual idle logistics resources are also used to deal with distribution needs. Analyzing customer shopping behavior by the big data technology to determine customer’s logistics preference on the basis of dividing the customer’s logistics preference into high speed, low cost, and low pollution and then constructing the corresponding objective function model according to different logistics preferences, we obtain the intensive distribution logistics network model and solve it with heuristic algorithm. Furthermore, this paper analyzes the mechanism of interest distribution of the participants in the distribution network and puts forward an improved interval Shapley value method considering both satisfaction and contribution, with case verifying the feasibility and effectiveness of the model. The results showed that, compared with the traditional Shapley method, distribution coefficient calculated by the improved model could be fairer, improve stakeholder satisfaction, and promote the sustainable development of the alliance as well.
Identity of G<sub>A1</sub>, G<sub>M1a</sub> and G<sub>D1b</sub> synthase in Golgi vesicles from rat liver (1989)

Competition experiments using GM1b, GD1a and GT1b as substrates, and as mutual inhibitors for ganglioside sialyltransferase activity in preparations of Golgi vesicles derived from rat liver, suggested that sialyl transfer to these three respective compounds, leading to gangliosides GD1C, GT1a and GQ1b, respectively, is catalyzed by one enzyme. These results are incorporated into a model for ganglioside biosynthesis and its regulation.
Point cloud segmentation with LIDAR reflection intensity behavior (2012)

Light Detection and Ranging (LIDAR) scans are increasingly being used for 3D map construction and reverse engineering. The utility and benefit of the processed data maybe enhanced if the objects and geometry of the area scanned can be segmented and labeled. In this paper, we present techniques to model the intensity of the laser reflection return from a point during LIDAR scanning to determine diffuse and specular reflection properties of the scanned surface. Using several illumination models, the reflection properties of the surface are characterized by Lambertian diffuse reflection model and Blinn-Phong, Gaussian and Beckmann specular models. Experimental set up with eight different surfaces with varied textures and glossiness enabled measurement of algorithm performance. Examples of point cloud segmentation with the presented approach are presented.
Antibiotic Radioprotection of Mice Exposed to Supralethal Whole-Body Irradiation Independent of Antibacterial Activity (1976)

Anthony Mastromarino, Raphael Wilson, Antibiotic Radioprotection of Mice Exposed to Supralethal Whole-Body Irradiation Independent of Antibacterial Activity, Radiation Research, Vol. 68, No. 2 (Nov., 1976), pp. 329-338
An update on Huntington's disease (2014)

The premotor stage of Huntington's disease provides an ideal time to trial disease-modifying therapy, but reliable biomarkers are required for monitoring disease progression, and this remains an area of intense research. Our understanding of the underlying pathophysiological mechanisms continues to expand, and a number of promising therapeutic strategies are emerging, including strategies to silence mutant huntingtin expression.
Coding Time-Varying Signals Using Sparse, Shift-Invariant Representations (1998)

A common way to represent a time series is to divide it into shortduration blocks, each of which is then represented by a set of basis functions. A limitation of this approach, however, is that the temporal alignment of the basis functions with the underlying structure in the time series is arbitrary. We present an algorithm for encoding a time series that does not require blocking the data. The algorithm finds an efficient representation by inferring the best temporal positions for functions in a kernel basis. These can have arbitrary temporal extent and are not constrained to be orthogonal. This allows the model to capture structure in the signal that may occur at arbitrary temporal positions and preserves the relative temporal structure of underlying events. The model is shown to be equivalent to a very sparse and highly overcomplete basis. Under this model, the mapping from the data to the representation is nonlinear, but can be computed efficiently. This form also allows the use o...
Mobile Phone Anomalous Behaviour Detection for Real-time Information Theft Tracking (2011)

Abstract—Due to the prevalence of mobile phones usage and their increasing features and functionalities, the amount of personal and confidential data residing in the phones is becoming substantial. In the event of information theft by applications residing on the phones, the loss of such important data can be damaging to the user’s reputation or result in a financial loss. We show in this paper how these applications can appear to be non-malicious but are stealthily retrieving and exporting confidential information without leaving any trace, thus bypassing detections by current state-of-the-art anti-virus solutions. We propose a tool to detect and track the behaviour of these applications in real-time so as to collect evidence. Using this tool, we can successfully monitor the applications non-intrusively, detect the “misbehaving ” applications, alert the users, and log the evidence of malicious activities with timestamp information to facilitate forensic investigations and institute accountability.
Evaluation of higher-order time-domain perturbation theory of photon diffusion on breast-equivalent phantoms and optical mammograms (2007)

Time-domain perturbation theory of photon diffusion up to third order was evaluated for its accuracy in deducing optical properties of breast tumors using simulated and physical phantoms and by analyzing 141 projection mammograms of 87 patients with histology-validated tumors that had been recorded by scanning time-domain optical mammography. The slightly compressed breast was modeled as (partially) homogeneous diffusely scattering infinite slab containing a scattering and absorbing spherical heterogeneity representing the tumor. Photon flux densities were calculated from densities of transmitted photons, assuming extended boundary conditions. Explicit formulas are provided for second-order changes in transmitted photon density due to the presence of absorbers or scatterers. The results on phantoms obtained by perturbation theory carried up to third order were compared with measured temporal point spread functions, with numerical finite-element method (FEM) simulations of transmitted photon flux density, with results obtained from the diffraction of diffuse photon density waves, and from Pad\'e approximants. The breakdown of first-, second-, and third-order perturbation theory is discussed for absorbers and a general expression was derived for the convergence of the Born series in this case. Taking tumor optical properties derived by the diffraction model as reference we conclude that estimates of tumor absorption coefficients by perturbation theory agree with reference values within $\ifmmode\pm\else\textpm\fi{}25%$ in only 65% (first order), 66% (second order), and 77% (third order) of all mammograms analyzed. In the remaining cases tumor absorption is generally underestimated due to the breakdown of perturbation theory. On average the empirical Pad\'e approximants yield tumor absorption coefficients similar to third-order perturbation theory, yet at noticeable lower computational efforts.
The Hormones: Physiology, Chemistry and Applications. (1949)

The hormones: physiology, chemistry, and applications , The hormones: physiology, chemistry, and applications , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Ligand Specificity of Serum Amyloid P Component (1983)

Conference Abstract| September 01 1983 Ligand Specificity of Serum Amyloid P Component C.R.K. Hind; C.R.K. Hind 1Immunological Medicine Unit, Department of Medicine, Royal Postgraduate Medical School, London W12 OHS Search for other works by this author on: This Site PubMed Google Scholar P.M. Collins; P.M. Collins *Department of Chemistry, Birkbeck College, London WC1E 7HX Search for other works by this author on: This Site PubMed Google Scholar M.B. Pepys M.B. Pepys 1Immunological Medicine Unit, Department of Medicine, Royal Postgraduate Medical School, London W12 OHS Search for other works by this author on: This Site PubMed Google Scholar Clin Sci (Lond) (1983) 65 (3): 17P. https://doi.org/10.1042/cs065017P Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation C.R.K. Hind, P.M. Collins, M.B. Pepys; Ligand Specificity of Serum Amyloid P Component. Clin Sci (Lond) 1 September 1983; 65 (3): 17P. doi: https://doi.org/10.1042/cs065017P Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search nav search search input Search input auto suggest search filter All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1983 The Biochemical Society and the Medical Research Society1983 Article PDF first page preview Close Modal You do not currently have access to this content.
Clindamycin and quinolone therapy for Bacillus anthracis Sterne infection in 60Co-gamma-photon-irradiated and sham-irradiated mice (2005)

Treatment with clindamycin, ciprofloxacin or moxifloxacin increased survival in sham-irradiated and gamma-irradiated animals challenged intratracheally with B. anthracis Sterne spores. However, the combination of clindamycin and ciprofloxacin increased mortality associated with B. anthracis Sterne infection, particularly in gamma-irradiated animals.
Human embryo component detection using computer vision (2017)

This thesis focuses on automatic identification of various components of human embryos in Hoffman Modulation Contrast (HMC) microscopic embryo images at early stages of growth from Day-1 to Day-5. Our primary motivation is to develop an automated system that would assist embryologists to study and analyze the behavior of developing preimplantated embryos in an attempt to improve In-Vitro Fertilization (IVF) outcomes. Through this thesis, we propose three novel methods for identification of various parts of human embryo. The main contribution of this thesis is to efficiently and reliably determine the boundaries of embryonic cells in Day-1 to Day-3 of HMC human embryo images. The proposed method is a model-based one that utilizes global ellipsoidal models conforming to the local image features such as edges and normals. It is an iterative approach through which image features contribute only to one candidate and will be retired once associated with that model candidate. An overall Precision and Sensitivity of 92% and 88% are achieved. Another contribution of this thesis is to segment different components of Day-5 embryos (also known as blastocysts) in HMC images as size and properties of these regions play an important role in grading and selecting viable embryos. A new method, called Segmentation using Neural Network in Compressed Domain (SNNCD), is developed to segment all three regions (Zona Pellucida (ZP), Trophectoderm (TE) and Inner Cell Mass (ICM)) in compressed blastocyst images. We exploit valuable features of a DCT transform to train a 2-layer feedforward backpropagation neural network. The overall Precision of 0.80, 0.69 and 0.76 and Sensitivity of 0.81, 0.80 and 0.56 for the ZP, TE and ICM detection in test data are achieved, respectively. Last, we propose a two-stage pipeline, called Segmentation using Fully Convolutional Network (SFCN) that first uses a preprocessing step to remove artifacts from the input images, which are then used by the Fully Convolutional Networks (FCN) to identify ICM regions. We also propose a data augmentation technique to avoid overfitting. The performance of the proposed pipeline is evaluated based on Accuracy and Overall Quality (OQ). This method improves SNNCD results on ICM segmentation by about 28% on OQ.
Differential Effects of Immunophilin-Ligands (FK506 and V-10,367) on Survival and Regeneration of Rat Retinal Ganglion Cells <i>In Vitro</i> and after Optic Nerve Crush <i>In Vivo</i> (2003)

Immunophilins belong to the large family of peptidyl-prolyl-cis-trans-isomerases known to be involved in many cellular processes (e.g., protein trafficking and transcriptional regulation). Beside the widespread therapeutic use of ligands of immunophilins as immunosuppressants, it has been shown that some of these compounds such as FK506 and V-10,367 may mediate neuroprotection and improve axonal regeneration following damage to peripheral nerve fibers. Here, we have analyzed the effects of these two compounds on neurite outgrowth of retinal explants in vitro and on axonal regeneration of retinal ganglion cells, a population of central intrinsic neurons, ten days following optic nerve crush in vivo. FK506 enhanced neurite outgrowth/regrowth in vitro in a dose dependent manner up to 135% (control = 100%), while V-10,367 was more effective (up to 168%). In vivo, intravitreal V-10,367 and FK506 significantly reduced the number of dying retinal ganglion cells as demonstrated by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling. Local application of FK506 into the vitreous body, but not V-10,367, immediately provided after the optic nerve crush induced the elongation of regenerating fibers across the lesion site for around 1.2 mm. Our data provide evidence that the ligands of the FK506-binding proteins FK506 and V-10,367 protect (otherwise dying) retinal ganglion cells from optic nerve crush-induced cell death, promote neurite outgrowth in vitro and that locally applied FK506 enhances the sprouting of axotomized central intrinsic neurons such as retinal ganglion cells in vivo after optic nerve crush.
Hepatitis B prevention, diagnosis, treatment and care: a review (2011)

Hepatitis B virus (HBV) infection is a major cause of morbidity and mortality worldwide. Chronic hepatitis B (CHB) infection is associated with an increased risk of cirrhosis, hepatic decompensation and hepatocellular carcinoma (HCC). The likelihood of developing CHB is related to the age at which infection is acquired; the risk being lowest in adults and >90% in neonates whose mothers are hepatitis B e antigen positive. Treatment of CHB infection aims to clear HBV DNA and prevent the development of complications. There are currently seven drugs available for the treatment of CHB: five nucleos(t)ide analogues and two interferon-based therapies. Long-term treatment is often required, and the decision to treat is based on clinical assessment including the phase of CHB infection and the presence and extent of liver damage. A safe and effective HBV vaccine has been available since the early 1980s. Vaccination plays a central role in HBV prevention strategies worldwide, and a decline in the incidence and prevalence of HBV infection following the introduction of universal HBV vaccination programmes has been observed in many countries including the USA and parts of South East Asia and Europe. Post-exposure prophylaxis (PEP) with HBV vaccine +/- hepatitis B immunoglobulin is highly effective in preventing mother to child transmission and in preventing transmission following sharps injuries, sexual contact and other exposures to infected blood and body fluids. Transmission of HBV in the health care setting has become an increasingly rare event in developed nations. However, it remains a significant risk in developing countries reflecting the higher prevalence of CHB, limited access to HBV vaccination and PEP and a lack of adherence to standard infection control precautions.
Scattering Lens Resolves Sub-100 nm Structures with Visible Light (2011)

The smallest structures that conventional lenses are able to optically resolve are of the order of 200 nm. We introduce a new type of lens that exploits multiple scattering of light to generate a scanning nanosized optical focus. With an experimental realization of this lens in gallium phosphide we imaged gold nanoparticles at 97 nm optical resolution. Our work is the first lens that provides a resolution better than 100 nm at visible wavelengths.