gebhart/patrepeval huggingface dataset:
Cross-Sectional Measurements and Extrapolations of Ultrasonic Fields (1985)

Ultrasonic fields produced by a disk transducer have been measured in two planes normal to the transducer axis and then extrapolated from one measurement plane to the other and also back to the face of the transducer. The measurements were performed with a small PVF hydrophone and a quadrature detector which yielded kthe complex values of the pressure at regularly spaced points in the scanned planes. Wave field extrapolation was carried out digitally using Fourier transformation methods which characterize the propagation of a field from one plane to another as a linear filtering operation. The filtering process was implemented as a product of the angular spectrum of the measured pressure field and a propagation matrix comprised of phase factors computer from parameters which included the wavelength of the measured field, the distance over which the field was to be extrapolated, and a maximum spatial frequency. The extrapolated field was then obtained by inverse Fourier transformation of the angular spectrum-phase matrix product. Comparisons of extrapolation results with measured data and with theoretical predictions show reasonable agreement and also demonstrate the sensitivity of the extrapolation process to the extent and shape of the spatial frequency window employed to determine the non-zero elements in the phase matrix. The results indicate fields can be extrapolated more accurately by sampling higher than the Nyquist rate and extending the size of the plane over which the measurements are made.
Microstructure of Mica‐Based Nanocomposite Glass‐Ceramics (1993)

A high‐strength machinable glass‐ceramic was prepared by controlling the crystallization of ZrO 2 ‐containing Ca 0.43 K 0.14 Mg 3 (Si 3 AlO 10 )F 2 glass. A unique microstructure of the glass‐ceramic was observed, using transmission electron microscopy (TEM): zirconia particles of nanometer size, 20–50 nm, were embedded in calcium mica crystal. After zirconia particles grew in nanometer size, the mica crystals were precipitated to embed the particles. The particles were identified as transformable tetragonal zirconia crystals. This texture leads to high strength (500 MPa in bending) and good machinability.
Fabrication and non-covalent modification of highly oriented thin films of a zeolite-like metal–organic framework (ZMOF) with rho topology (2014)

Here we report the fabrication of the first thin film of a zeolite-like metal–organic framework (ZMOF) with rho topology (rho-ZMOF-1, ([In48(HImDC)96]48−)n) in a highly oriented fashion on a gold-functionalized substrate. The oriented rho-ZMOF-1 film was functionalized by non-covalent modification via post-synthetic exchange of different probe molecules, such as acridine yellow, methylene blue, and Nile red. In addition, encapsulation of a porphyrin moiety was achieved via in situ synthesis and construction of the rho-ZMOF. Adsorption kinetics of volatile organic compounds on rho-ZMOF-1 thin films was also investigated. This study suggests that rho-ZMOF-1 thin films can be regarded as a promising platform for various applications such as sensing and catalysis.
Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners (2005)

Several pleckstrin-homology (PH) domains with the ability to bind phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5)P3, PIP3] were expressed as green fluorescent protein (GFP) fusion proteins to determine their effects on various cellular responses known to be activated by PIP3. These proteins comprised the PH domains of Akt, ARNO, Btk or GRP1, and were found to show growth-factor-stimulated and wortmannin-sensitive translocation from the cytosol to the plasma membrane in several cell types, indicating their ability to recognize PIP3. Remarkably, although overexpressed Akt-PH-GFP and Btk-PH-GFP were quite potent in antagonizing the PIP3-mediated activation of the Akt protein kinase, such inhibition was not observed with the other PH domains. By contrast, expression of the PH domains of GRP1 and ARNO, but not of Akt or Btk, inhibited the attachment and spreading of freshly seeded cells to culture dishes. Activation of PLCgamma by epidermal growth factor (EGF) was attenuated by the PH domains of GRP1, ARNO and Akt, but was significantly enhanced by the Btk PH domain. By following the kinetics of expression of the various GFP-fused PH domains for several days, only the PH domain of Akt showed a lipid-binding-dependent self-elimination, consistent with its interference with the anti-apoptotic Akt signaling pathway. Mutations of selective residues that do not directly participate in PIP3 binding in the GRP1-PH and Akt-PH domain were able to reduce the dominant-negative effects of these constructs yet retain their lipid binding. These data suggest that interaction with and sequestration of PIP3 may not be the sole mechanism by which PH domains interfere with cellular responses and that their interaction with other membrane components, most probably with proteins, allows a more specific participation in the regulation of specific signaling pathways.
In vitro studies of core peptide‐bearing immunopotentiating reconstituted influenza virosomes as a non‐live prototype vaccine against hepatitis C virus (2002)

Evidence from both animal and human viral diseases indicate that cytotoxic T lymphocytes (CTL) are crucial in antiviral defense. However, a major problem to generate cytotoxic immunity is that in vivo exogenous antigens are usually presented via MHC class II pathway and normally fail to induce CTL. The aim of this study is to describe a novel non-live prototype vaccine based on immunopotentiating reconstituted influenza virosomes (IRIV) as vehicles to deliver HLA-A*0201-restricted hepatitis C virus (HCV) peptides (core 35-44 and 131-140) into the cytoplasm of at least three different target cell types [including T2, a transporter associated with antigen processing (TAP)-deficient cell line] resulting in MHC class I peptide presentation and lysis by peptide-specific CTL lines. Comparison of kinetics and analysis of the influence of peptide-stripping and Brefeldin A (BFA) reveal that there exists an endogenous, TAP-independent and BFA-sensitive pathway for virosomally delivered peptides. Moreover, virosomes containing influenza matrix peptide 58-66 can efficiently re-stimulate in vivo primed CTL and, importantly, IRIV containing HCV core peptides can even prime CTL from peripheral blood mononuclear cells of HCV(-) healthy blood donors in vitro. The fact that in vitro primed CTL are also able to specifically lyse target cells infected with recombinant vaccinia virus encoding the HCV core protein is of great importance for future studies based on in vivo mouse models. One of the most evident advantages of the virosomes in vivo will be their capability to protect the incorporated peptide from a large variety of degrading proteases.
Transfer of Phosphoryl Group between Two Regulatory Proteins Involved in Osmoregulatory Expression of the ompF and ompC Genes in Escherichia coli (1989)

EnvZ is a cytoplasmic membrane protein which is involved in osmoregulatory expression of the ompF and ompC genes in Escherichia coli possibly by sensing the environmental osmotic signal. A truncated form of the EnvZ protein (EnvZ*), comprising 82% of EnvZ starting from the C terminus, was purified to homogeneity. The purified EnvZ* was autophosphorylated with ATP. The phosphoryl group on EnvZ* could then be rapidly transferred to OmpR, which is a positive regulator of the ompF and ompC genes and which was proposed to interact with EnvZ in the process of osmoregulation. In the presence of ATP, the phosphorylated OmpR was rapidly dephosphorylated. These results suggest that the transfer of the phosphoryl group between EnvZ and OmpR plays an important role in the signaling pathway in osmoregulation.
Combinatorial sketching for finite programs (2006)

Sketching is a software synthesis approach where the programmer develops a partial implementation - a sketch - and a separate specification of the desired functionality. The synthesizer then completes the sketch to behave like the specification. The correctness of the synthesized implementation is guaranteed by the compiler, which allows, among other benefits, rapid development of highly tuned implementations without the fear of introducing bugs.We develop SKETCH, a language for finite programs with linguistic support for sketching. Finite programs include many highperformance kernels, including cryptocodes. In contrast to prior synthesizers, which had to be equipped with domain-specific rules, SKETCH completes sketches by means of a combinatorial search based on generalized boolean satisfiability. Consequently, our combinatorial synthesizer is complete for the class of finite programs: it is guaranteed to complete any sketch in theory, and in practice has scaled to realistic programming problems.Freed from domain rules, we can now write sketches as simpleto-understand partial programs, which are regular programs in which difficult code fragments are replaced with holes to be filled by the synthesizer. Holes may stand for index expressions, lookup tables, or bitmasks, but the programmer can easily define new kinds of holes using a single versatile synthesis operator.We have used SKETCH to synthesize an efficient implementation of the AES cipher standard. The synthesizer produces the most complex part of the implementation and runs in about an hour.
Use of Synchronized Phasor measurement System for Enhancing AC-DC Power System Transmission Reliability and Capability (2004)

This paper is discussing the use of Synchronized Phasor Measurement Technology, which is now being used for monitoring power system status and dynamic transient event recording at Southern California Edison (SCE). This system is expected to enhance AC-DC power transmission system reliability and capability by monitoring the phase angles and oscillations at several substations and two remote DC terminals. The system could be used for HVDC power modulation in future. SCE has been working aggressively on this Synchronized Phasor measurement technology for over eight years and obtains data from fourteen Phasor Measurement Units (PMUs) and the two Phasor Data Concentrators (PDC) on its system. The data from the PMUs is now being collected and being used for analysis of system disturbances. SCE also obtains the data from Bonneville Power Administration Grand Coulee generating substation, which is over 900 miles away, and close to the Northern HVDC Pacific Inter-tie terminal and monitors the phase angle between the north and the south HVDC Pacific Inter-tie terminals. SCE is continuing to work on this technology with Bonneville Power Administration (BPA) and Los Angeles Water and Power to investigate the possibility implementing it for real-time monitoring and control. SCE is also working with other Western Electric Coordinating Council (WECC) members for information exchange. It is believed that the technology has great potential for enhancing power system stability and power transmission system capability of an AC-DC inter-tie system. This technology is also being used for monitoring the system stability and resulting information can assist in avoiding major system disturbances like the one that occurred on August 10, 1996 in WECC and on August 14, 2003 in Northeast United States and Canada.
Minimising Dynamic Power Consumption in On-Chip Networks (2006)

The provision of a general-purpose on-chip communication network is becoming increasingly important in the design of complex SoCs and chip-multiprocessors. In this paper we explore how the power consumed by such on-chip networks may be reduced through the application of clock and signal gating optimisations. We describe how the effectiveness of such optimisations may be maximised and demonstrate that very large reductions in power requirements are possible. A detailed analysis of where power is consumed in an optimised on-chip network is then provided. Results are obtained from fully place and routed standard-cell designs implemented in a 90nm technology. Our 64-bit on-chip network has a maximum operating frequency of 800MHz, in the best-case the combined latency for traversing a network router and link is a single clock cycle
Recent Experimental Investigations of Vocal Pitch in Speech (1940)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Grant Fairbanks; Recent Experimental Investigations of Vocal Pitch in Speech. J Acoust Soc Am 1 April 1940; 11 (4): 457–466. https://doi.org/10.1121/1.1916060 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Modeling of ground penetrating radar data in stratified media (2004)

Modeling of GPR data is important because it helps us to interpret the GPR data and constitutes the basis for many inversion schemes. Horizontally layered media are very often encountered in geological systems, and therefore, it is important to develop a very fast and robust modeling technique that can be used for inversion of GPR data in these systems. We adapted and implemented the invariant imbedding or reflectivity technique (originally developed by Kennett to model elastic waves in layered media) for modeling of GPR data in layered isotropic media. The results obtained with this technique are in excellent agreement with those obtained from the Fresnel's equations and FDTD algorithms.
Accuracy of invasive arterial pressure monitoring in cardiovascular patients: an observational study (2014)

Physicians should be aware of the possibility that IBP can be inaccurate in a consistent number of patients due to underdamping/resonance phenomena. NIBP measurement may help to confirm/exclude the presence of this artifact avoiding inappropriate treatments.
Hemophilia B Mutational Analysis (2003)

Since the cloning of the factor IX gene in 1982 (1), there have been several strategies employed for the identification of mutations in the mutationally heterogeneous hemophilia B population. Initially, such strategies inevitably employed Southern blotting to screen for gross deletions (2) or restriction site alterations (3), and cloning of the patients genomic DNA (4). However, with the advent of polymerase chain reaction (PCR) using a thermostable DNA polymerase (5), cloning has become superfluous, and factor IX mutations can be identified simply by direct DNA sequencing of PCR-amplified sections of the factor IX gene (6). From 1988 onwards, a new method of screening PCR products for mutations was developed in our laboratory (7) based on the chemical cleavage of mismatch method which was first used on cloned DNA (8). This procedure, capable of detecting 100% of mutations, is useful for screening a large number of patients who are all expected to have different mutations, prior to sequencing the PCR product. However, it is probably quicker simply to sequence the products straightaway if only a handful of patients are to be examined (6).
Three‐Dimensional Co<sub>3</sub>O<sub>4</sub>@MnO<sub>2</sub> Hierarchical Nanoneedle Arrays: Morphology Control and Electrochemical Energy Storage (2014)

In this paper, a highly ordered three‐dimensional Co 3 O 4 @MnO 2 hierarchical porous nanoneedle array on nickel foam is fabricated by a facile, stepwise hydrothermal approach. The morphologies evolution of Co 3 O 4 and Co 3 O 4 @MnO 2 nanostructures upon reaction times and growth temperature are investigated in detail. Moreover, the as‐prepared Co 3 O 4 @MnO 2 hierarchical structures are investigated as anodes for both supercapacitors and Li‐ion batteries. When used for supercapacitors, excellent electrochemical performances such as high specific capacitances of 932.8 F g −1 at a scan rate of 10 mV s −1 and 1693.2 F g −1 at a current density of 1 A g −1 as well as long‐term cycling stability and high energy density (66.2 W h kg −1 at a power density of 0.25 kW kg −1 ), which are better than that of the individual component of Co 3 O 4 nanoneedles and MnO 2 nanosheets, are obtained. The Co 3 O 4 @MnO 2 NAs are also tested as anode material for LIBs for the first time, which presents an improved performance with high reversible capacity of 1060 mA h g −1 at a rate of 120 mA g −1 , good cycling stability, and rate capability.
Liposomal Delivery of Peptides and Proteins (1995)

Controlled delivery of peptide and protein drugs constitutes a major challenge. As these compounds are generally not therapeutically active after oral administration, the parenteral route is the preferred route for their administration. However, when administered parenterally, they often show a very short circulation and biological half-life necessitating repeated injections. Further medical application and commercialization of these agents requires development of viable delivery systems to improve their therapeutic behavior (1–3). In this contribution examples of liposomal delivery approaches for peptides and proteins will be briefly described. These examples include the parenteral delivery of vasopressin, interleukin-2, tissue plasminogen activator, diphtheria toxin, and prodrug activating enzymes, and the oral delivery of antigens.
The development of harmonic distortion in pulsed finite-amplitude ultrasound passing through liver (1986)

The progressive development of finite-amplitude distortion of ultrasonic pulses has been investigated in excised bovine liver using pulsed focused ultrasonic beams at nominal frequencies of 2.5 and 3.5 MHz. Both the transducers and the powers used were those which may be encountered with clinical imaging equipment. Significant distortion of the waveform was observed to occur, particularly at higher powers. For example, at 2.5 MHz, with a mean input pressure (p0) of 0.58 MPa, the second harmonic in the pulse spectrum showed a maximum value of 10.5 dB below the fundamental and the highest third harmonic component was 19 dB below the fundamental. These particular observations illustrate that finite-amplitude distortion may be of considerable significance in the transmission through tissue of ultrasonic pulses during diagnostic scanning.
The destination of Iowa’s commercial corn (1934)

Iowa's commercial corn represents only 15 percent of the total crop, yet that 15 percent returns from 9 to 12 percent of Iowa’s farm income.\nThree-fourths of the 63 million bushels of commercial corn originate in 35 of the 99 counties.\nOver 50 percent of the commercial corn leaves the state on first billing, of which 42 percent goes direct to terminal markets.\nOf the reshipments from Iowa’s primary markets 85 percent goes outside the state—23 percent reaches terminal markets.\nGrain handling agencies located at Iowa’s primary markets place a larger percentage of total shipments into the hands of the ultimate consumer than does the country shipper. This is true because the agencies at the primary markets have far-reaching contacts with both the surplus and deficit areas and they are able to merchandise grain enroute to the ultimate consumer.
Intelligent distributed architecture (IDA) for mobile sensor data fusion (2009)

In this paper, we provide a new two-layer scalable architecture, intelligent distributed architecture (IDA). The first layer of IDA, the application layer, is responsible for the mission specific tasks. The second layer, the network layer, is responsible for relaying the information quickly to reduce latency. In order to increase efficiency, we propose an intelligent network layer that evaluates the network traffic through application provided policies. The evaluation assesses improved accuracy in bandwidth limited scenarios. IDA policies permit the application to drop, merge or modify the packets in real time from different sources. We demonstrate how this architecture can be applied to an example application, distributed target tracking. We also propose some new algorithms that can be used in conjunction with IDA for target tracking. Our experiments on this application show that IDA improves system performance when the bandwidth is limited.
Micrometer patterning of phthalocyanines by selective chemical vapor deposition (1991)

Micrometer size patterns of copper phthalocyanine derivatives were fabricated from 1,2,4,5-tetracyanobenzene (TCNB) by a selective chemical vapor deposition method. Copper films were patterned on silicon wafers by photolithography and wet etching techniques, sealed in a glass tube with TCNB, and heated at different temperatures. Controlling the treatment temperature, selective chemical vapor deposition was achieved to produce copper phthalocyanine thin films on the copper patterns. After thermal annealing of the deposited film in vacuum, the films were converted to a polymer of the copper phthalocyanines.
Cardiovascular Magnetic Resonance in Acute ST-Segment–Elevation Myocardial Infarction (2018)

Although mortality after ST-segment elevation myocardial infarction (MI) is on the decline, the number of patients developing heart failure as a result of MI is on the rise. Apart from timely reperfusion by primary percutaneous coronary intervention, there is currently no established therapy for reducing MI size. Thus, new cardioprotective therapies are required to improve clinical outcomes after ST-segment-elevation MI. Cardiovascular magnetic resonance has emerged as an important imaging modality for assessing the efficacy of novel therapies for reducing MI size and preventing subsequent adverse left ventricular remodeling. The recent availability of multiparametric mapping cardiovascular magnetic resonance imaging has provided new insights into the pathophysiology underlying myocardial edema, microvascular obstruction, intramyocardial hemorrhage, and changes in the remote myocardial interstitial space after ST-segment-elevation MI. In this article, we provide an overview of the recent advances in cardiovascular magnetic resonance imaging in reperfused patients with ST-segment-elevation MI, discuss the controversies surrounding its use, and explore future applications of cardiovascular magnetic resonance in this setting.