gebhart/patrepeval huggingface dataset:
The rat liver epithelial (RLE) cell nuclear protein database (1993)

The master two-dimensional computer database of rat liver epithelial (RLE) cellular proteins (Wirth et al., Electrophoresis 1991, 12, 931-954) has been expanded to include detailed information concerning 1100 nucleoplasmic (cytosolic) and 850 particulate associated [35S]methionine labeled as well as 215 nucleoplasmic and 269 particulate associated [32P]orthophosphate labeled RLE nuclear polypeptides, respectively. The RLE nuclear protein database developed using the Elsie 5 gel analysis system contains both qualitative and quantitative annotations including polypeptide identification number, protein name (if known), molecular weight and pI information, quantitation and polypeptide spot shape, subcellular location, as well as specific information regarding transformation (chemical and spontaneous) and growth-related characteristics. Microsequencing of polypeptides directly from two-dimensional (2-D) blotted membranes has recently been established in our laboratory and provides a highly efficient and rapid means of polypeptide identification in the absence of specific antibodies. At present the RLE protein database is still in the developmental stage and is continually being updated as additional information is obtained. Nonetheless, it is anticipated that knowledge obtained concerning the identification and characterization of specific transformation and/or growth regulatory proteins in the RLE in vitro cell system will not only have direct application to other rodent and human 2-D protein databases currently under development but will also complement them.
Watch+Strap: Extending Smartwatches with Interactive StrapDisplays (2020)

While smartwatches are widely adopted these days, their input and output space remains fairly limited by their screen size. We present StrapDisplays-interactive watchbands with embedded display and touch technologies-that enhance commodity watches and extend their input and output capabilities. After introducing the physical design space of these StrapDisplays, we explore how to combine a smartwatch and straps in a synergistic Watch+Strap system. Specifically, we propose multiple interface concepts that consider promising content distributions, interaction techniques, usage types, and display roles. For example, the straps can enrich watch apps, display visualizations, provide glanceable feedback, or help avoiding occlusion issues. Further, we provide a modular research platform incorporating three StrapDisplay prototypes and a flexible web-based software architecture, demonstrating the feasibility of our approach. Early brainstorming sessions with 15 participants informed our design process, while later interviews with six experts supported our concepts and provided valuable feedback for future developments.
Separation of Living and Dead Cells by Dielectrophoresis (1966)

High-frequency non-uniform electric fields were used to cause selective dielectrophoresis of yeast cells in an aqueous medium. Living cells separated from admixed dead ones remained viable after the separation process.
Morphology of Porous and Wrinkled Fibers of Polystyrene Electrospun from Dimethylformamide (2009)

Submicron diameter fibers of polystyrene are electrospun from solutions in dimethylformamide (DMF). When electrospun in a high-humidity environment, the interior of these fibers was found to be highly porous rather than consolidated, despite the smooth and nonporous appearance of the fiber surfaces. The formation of interior porosity is attributed to the miscibility of water, a nonsolvent for the polymers in solution, with DMF. The resulting morphology is a consequence of the relatively rapid diffusion of water into the jet, leading to a liquid−liquid phase separation that precedes solidification due to evaporation of DMF from the jet. When electrospun in a low-humidity environment, the fibers exhibit a wrinkled morphology that can be explained by a buckling instability. Understanding which morphology forms under a given set of conditions is achieved through the comparison of three characteristic times: the drying time, the buckling time, and the phase separation time. The morphology has important consequences for the properties of the fibers such as their mechanical strength and stiffness.
Recovery of Propionic and Acetic Acids from Fermentation Broth by Electrodialysis (1992)

Abstract Acetic and propionic acids can be produced by fermentation. In this process, acid recovery is important both for producing a concentrated product from the broth and for removing acid from the broth to reduce product inhibition during the fermentation. The purpose of this work was to characterize the performance of an electrodialysis unit for carrying out both tasks. Current efficiencies, water transport, and product concentrations were determined both for model solutions of the acids and for fermentation broths to determine the limiting factors in using this separation method. In addition, observations were made of fouling behavior of the membranes in this use. The highest concentrations of product were obtained by contacting with the most concentrated feed and doing so in the absence of competing ions. For the range studied here, a maximum concentration of 13.8% (w/v) sodium propionate was obtained. In the batch recycle mode, final concentrations in the concentrate were reduced, but acid recoveries were improved by the presence of other ions because the low‐current shut‐off was delayed. The use of electrodialysis for producing a concentrated acid product is not promising unless salt levels in the medium can be reduced and acid levels increased. However, electrodialysis can be used to maintain low acid levels in the fermentor during extractive fermentation.
Robotic System for MRI-Guided Stereotactic Neurosurgery (2014)

Stereotaxy is a neurosurgical technique that can take several hours to reach a specific target, typically utilizing a mechanical frame and guided by preoperative imaging. An error in any one of the numerous steps or deviations of the target anatomy from the preoperative plan such as brain shift (up to mm), may affect the targeting accuracy and thus the treatment effectiveness. Moreover, because the procedure is typically performed through a small burr hole opening in the skull that prevents tissue visualization, the intervention is basically “blind” for the operator with limited means of intraoperative confirmation that may result in reduced accuracy and safety. The presented system is intended to address the clinical needs for enhanced efficiency, accuracy, and safety of image-guided stereotactic neurosurgery for deep brain stimulation lead placement. The study describes a magnetic resonance imaging (MRI)-guided, robotically actuated stereotactic neural intervention system for deep brain stimulation procedure, which offers the potential of reducing procedure duration while improving targeting accuracy and enhancing safety. This is achieved through simultaneous robotic manipulation of the instrument and interactively updated in situ MRI guidance that enables visualization of the anatomy and interventional instrument. During simultaneous actuation and imaging, the system has demonstrated less than 15% signal-to-noise ratio variation and less than 0.20 geometric distortion artifact without affecting the imaging usability to visualize and guide the procedure. Optical tracking and MRI phantom experiments streamline the clinical workflow of the prototype system, corroborating targeting accuracy with three-ax- s root mean square error 1.38 ± 0.45 mm in tip position and 2.03 ± 0.58° in insertion angle.
Metal-to-ligand charge-transfer spectra of pentacyanoruthenate(II) complexes of aromatic nitrogen heterocycles (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal-to-ligand charge-transfer spectra of pentacyanoruthenate(II) complexes of aromatic nitrogen heterocyclesCraig R. Johnson and Rex E. ShepherdCite this: Inorg. Chem. 1983, 22, 17, 2439–2444Publication Date (Print):August 1, 1983Publication History Published online1 May 2002Published inissue 1 August 1983https://pubs.acs.org/doi/10.1021/ic00159a020https://doi.org/10.1021/ic00159a020research-articleACS PublicationsRequest reuse permissionsArticle Views350Altmetric-Citations62LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Development and Characterization of<i>In Situ</i>Oral Gel of Spiramycin (2014)

The present investigation deals with the optimization, formulation, and characterization of oral in situ gel of spiramycin. Sodium alginate and hydroxypropyl methylcellulose were used as cross-linking and viscosifying agents, respectively. Sodium bicarbonate was used as a floating agent. In preformulation studies, the melting point, pH, and partition coefficient were found to be 133 °C, 9.5, and 0.193, respectively. The drug had retention time at around 2.65 minutes in high performance liquid chromatography (HPLC). During compatibility studies of drug with all polymers, we observed that there were no changes in the FTIR spectra of a mixture of drug and polymers. All the formulations showed good pourability. Floating time and total floating time were ~30 sec and >12 hours, respectively. During in vitro drug release studies, the drug was released from the formulation around 80-100% for 12-16 hrs. In TEM analysis, we found that the drug molecules were well entrapped in the polymer and the drug was released slowly for up to 12 hrs. In these studies, we found that the concentration of sodium alginate and HPMC had significant influence on floating lag time, gelling capacity, and cumulative percentage drug release. During antimicrobial studies, we found that the formulation containing spiramycin showed good zone of inhibition against different microbial strains (Staphylococcus aureus and Escherichia coli).
Pharmacokinetics of bendroflumethiazide (1977)

Bendroflumethiazide (bft), 10 mg, was administered orally to 9 healthy volunteers. The concentrations of the diuretic in plasma and urine were determined by gas-liquid chromatography (GLC). Peak plasma levels (86 +/- 18 ng/ml) of bft were reached at 2 +/- 0.4 hr. The concentration declined with a mean t1/2 of 3.0 hr. The apparent volume of distribution averaged 1.48 L/kg. The major part of the drug was eliminated via nonrenal mechanisms, the nonrenal clearance being estimated to 269 +/- 77 ml/min and renal clearance to 105 +/- 24 ml/min. Urinary recovery of the thiazide averaged 30%.
PEB to development delay influence on contact patterning by negative tone development process (2013)

Negative tone development (NTD) process benefits the process latitude of dark field features such as contact holes and isolated trenches. Thus the NTD process has been a viable manufacture solution for aggressive-pitch contact patterning. Because the NTD process adopts organic solvent as developer to dissolve the de-protected photo-resist, it may conflict with conventional positive tone development on maximizing the photocell utilization. In the manufacturing implementation of NTD process, the off-line development is the most commonly adopted arrangement to maximize the flexibility of photocell dispatch. Therefore the post exposure bake to development delay (PEBDD) is a concern for thorough investigation to deliver robust NTD process. In this paper, PEBDD induced CD shrinkage was investigated for contact printing to explore the possible mechanism. The resist comparison, ambient contamination verification, baking temperature split of photo-resists were conducted for comparing the PEBDD effect. The experimental results suggested the photo acid concentration and photo acid diffusion are two most critical factors for PEBDD effect. Through the understanding of critical factors for PEBDD, the suitable operation on mitigating PEBDD influence as well as adequate queue time setting were proposed for robust process control.
Xeset 1-Saravan 115kv Transmission Line (Saravanh Province) Project (2006)

The Greater Mekong Sub-region Power Trade Project consists of mainly two construction works. One is the construction of a transmission line of 82km from Ban Hat substation to Stung Treng substation. Responsibility of the Laotian side is the 25.7km distance between Ban Hat Substation and the Lao-Cambodian border. The other construction work is the expansion of the existing Ban Hat Substation to connect the above-mentioned transmission lines. Based on the survey during the Initial Environmental Examination (IEE), no people will be resettled. Moreover, no structural assets, spiritual or cultural property will be affected. The main negative aspects will come from some permanent land losses and temporary land occupation. The affected people will be given every opportunity to have redress to their grievances.
Applied Dynamic Programming for Optimization of Dynamical Systems (2005)

Based on the results of over 10 years of research and development by the authors, this book presents a cross section of dynamic programming (DP) techniques applied to the optimization of dynamical systems. It provides applications of DP algorithms that are easily adapted to the reader's own interests and problems.
Controlled Synthesis of Monodisperse SiO<sub>2</sub>TiO<sub>2</sub> Microspheres with a Yolk–Shell Structure as Effective Photocatalysts (2012)

Monodisperse yolk-shell SiO(2) -TiO(2) microspheres were synthesized using core-shell silica microspheres as templates. In the absence of prior surface modifications, a uniform coating of the TiO(2) layer on the core-shell silica was achieved through a sol-gel route. Mesoporous silica shells between the outer TiO(2) shell and the SiO(2) core were selectively removed by using a weak base, yielding yolk-shell SiO(2) -TiO(2) microspheres (ys-SiO(2) @TiO(2) ). Using the same templates, we synthesized Pt-encased microspheres (SiO(2) @Pt-TiO(2) ), in which Pt nanoparticles are embedded between the SiO(2) core and the TiO(2) shell. Selective etching of the silica shells in SiO(2) @Pt-TiO(2) yields Pt-encased yolk-shell SiO(2) -TiO(2) microspheres (ys-SiO(2) @< Pt >TiO(2) ), which contain void spaces suitable for use as nanoreactors. The ys-SiO(2) @< Pt >TiO(2) catalyst shows enhanced hydrogen production from water under UV-light irradiation presumably as a result of multiple reflections within the void spaces and can be reused without losing their activity. Moreover, this core-shell template method is effective for the synthesis of other yolk-shell microspheres with different metal oxides.
Symbolic Mathematical Laboratory (1967)

A large computer program has been developed to aid applied mathematicians in the solution of problems in non-numerical analysis which involve tedious manipulations of mathematical expressions. The mathematician uses typed commands and a light pen to direct the computer in the application of mathematical transformations; the intermediate results are displayed in standard text-book format so that the system user can decide the next step in the problem solution. Three problems selected from the literature have been solved to illustrate the use of the system. A detailed analysis of the problems of input, transformation, and display of mathematical expressions is also presented.
Biomedical image segmentation (2002)

Segmentation of biomedical images separates scenes into their components based on recognition of locally similar patterns of intensity, color, texture or other features, with or without use of a priori knowledge regarding the objects or "camera" used to acquire the images. Segmented images are required for most types of object models, labeling, morphometry and geometrical investigations on imaged structures. Segmentation encompasses many methods-manual, semi-automatic and fully automatic-which are practical and useful in certain applications, as no general solution has emerged. The performance of segmentation methods is judged by comparison to manual methods, independent knowledge of truth, reproducibility and subjective criteria. Many of the methods used for segmentation can be interpreted as special cases of Grenander's (1993, 1997) global pattern analysis, a theoretical framework for the representation of biological shape and its variability.
Proteobacteria explain significant functional variability in the human gut microbiome (2017)

These results establish limits on functional redundancy and predict specific genes and taxa that may explain physiological differences between gut microbiomes.
Factors Influencing the DNA Content of Radiation-induced Micronuclei (1992)

The distribution of the DNA content of radiation-induced micronuclei was analysed in several cell lines (Chinese hamster, Syrian hamster and mouse NIH-3T3 cells) by flow cytometry. Frequency and DNA content of micronuclei were measured simultaneously using fluorescence and forward scatter signals of micronuclei and nuclei in suspension stained with ethidium bromide. Computerized random breakage of chromosomes and random combination of fragments was performed to compare the measured micronucleus distributions in synchronized cells irradiated during G1-phase with calculated distributions. The measured DNA distribution of radiation-induced micronuclei was found to be influenced by several factors: (1) the DNA distribution and the centromeric index of the chromosomes in the various cell lines; (2) the cell cycle phase at time of micronucleus measurement due to DNA synthesis in micronuclei; (3) the presence of chromosome fragments in micronuclei; and (4) the presence of whole chromosomes in micronuclei. These factors were shown to be responsible for the previously found large radiation-induced micronuclei which could not be explained by the classic assumption only that radiation-induced micronuclei are mainly produced by single acentric fragments.
Kinetics study for continuous transesterification of cottonseed oil in a static mixing tubular reactor to prepare biodiesel. (2011)

Fatty acid methyl esters were produced by continuous transesterification using cottonseed oil and methanol as raw materials in the presence of catalyst and cosolvent in a static mixing tubular reactor.The reaction was carried out under the condition of KOH as catalyst(0.6 %),molar ratio of methanol to cottonseed oil 28∶1,volume ratio of oil to cosolvent of butanone 1∶1.5.The kinetics of continuous transesterification reaction were studied under reaction temperature of 45 ℃,50 ℃,55 ℃,60 ℃ and 65 ℃ respectively.The results showed that the reaction can be finished in 15 minutes and the conversion of rapeseed oil was 98.7 %.The kinetic model from the experiment data was a pseudo-first-order reaction and activation energy of continuous transesterification was 11.9 kJ/mol.
Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma (2018)

Infection by chronic hepatitis B virus (HBV) is one of the major causes of liver cirrhosis and primary hepatocellular carcinoma (HCC). Viral DNA integration into the host cell genome is a key mechanism of hepatocarcinogenesis. However, the molecular characterization and the potential clinical implications of HBV DNA integration into patients suffering from different hepatitis and HCC remain unclear. In this study, we analyzed HBV integrations in patients with hepatitis B and HCC using HBV probe-based capturing and next-generation sequencing. The results revealed that the sizes of the HBV integrations ranged from 28 bp to 3215 bp, including the full-length HBV DNA sequence. The integration breakpoints were preferentially distributed in the viral enhancer, X protein, and core protein regions of the HBV genome. The number of HBV integrations followed an increasing trend from hepatitis to HCC, which was positively correlated with the HBV virus load in patients with hepatitis. The number of HBV integrations in the HBeAg positive chronic hepatitis B group was significantly greater than that in the other hepatitis B groups (P < 0.05). However, the relative abundance of HBV integrations was significantly higher in HCC tissues than in the adjacent liver tissues. Interestingly, 61.6% (8/13) of HBV-human DNA integration fragments could be detected at the RNA level. Our results also showed that HBV integration-targeted genes (ITGs) were significantly enriched in many cancer-related pathways, such as MAPK, extracellular matrix (ECM)-receptor interaction, and the hedgehog signaling pathway. Individuals with HBV integrations exhibited shorter disease-free survival (DFS) and overall survival (OS) than those without HBV integrations in some ITGs including LINC00293 (long intergenic non-protein coding RNA 293; DFS P = 0.008, OS P = 0.009), <i>FSHB</i> (follicle stimulating hormone beta subunit; DFS P = 0.05, OS P = 0.186), and <i>LPHN3</i> (latrophilin-3; DFS P = 0.493, OS P = 0.033). This study determined the underlying mechanism of HBV DNA integration in liver diseases and laid the foundation for future studies on the pathogenesis of liver cancer.
COMPARISON OF PREPARATION PROCEDURES OF BARIUM HYDROXYAPATITES (1998)

Four preparation procedures for barium hydroxyapatite have been compared. Of these only one produced high pure nonstoichiometric barium hydroxyapatite and can be recommended as facile preparation procedure.
Multilingual probabilistic topic modeling and its applications in web mining and search (2014)

Multilingual topic models are a fairly novel group of unsupervised, language-independent and generative machine learning models. This tutorial covers all key aspects of their probabilistic framework and demonstrates how to easily integrate these models into frameworks for cross-lingual and multilingual Web mining and search.
Gendered Work Conditions, Health, and Work Outcomes. (2003)

This cross-sectional study of nonfaculty university employees examined associations among gendered work conditions (e.g., sexism and discrimination), job demands, and employee job satisfaction and health. Organizational responsiveness and social support were examined as effect modifiers. Comparisons were made by gender and by the male-female ratio in each job category. The relationship of gendered conditions of work to outcomes differed on the basis of respondents' sex and the job sex ratio. Although the same predictors were hypothesized for job satisfaction, physical health, and psychological distress, there were some differing results. The strongest correlate of job satisfaction was social support; perceived sexism in the workplace also contributed for both men and women. Organizational factors associated with psychological distress differed between female- and male-dominated jobs.