gebhart/patrepeval huggingface dataset:
Plasma levels of fibrinolytic proteins and the risk of myocardial infarction in men (2010)

Hypofibrinolysis as measured with overall clot lysis assays is associated with risk of arterial thrombosis. Individual components of the fibrinolytic system, however, have not been studied extensively in relation to arterial disease, or results of studies were inconsistent. The relation between plasminogen and alpha2-antiplasmin levels and cardiovascular risk factors and the association between plasminogen, alpha2-antiplasmin, tissue-plasminogen activator (t-PA), and plasminogen activator inhibitor-1 (PAI-1) and risk of myocardial infarction was investigated in the Study of Myocardial Infarctions Leiden (555 men with a first myocardial infarction and 635 controls). alpha2-antiplasmin was associated with age and lipid levels, whereas plasminogen correlated with lipids, C-reactive protein, and smoking. Increased levels of all fibrinolytic factors were associated with myocardial infarction. Age-adjusted odds ratios (ORs; 95% confidence interval) for quartile 4 compared with 1 were 1.7 (1.2-2.3) for plasminogen, 1.9 (1.3-2.6) for alpha2-antiplasmin, 1.7 (1.2-2.3) for t-PA, and 1.7 (1.2-2.4) for PAI-1. After adjusting for cardiovascular risk factors, only alpha2-antiplasmin levels remained associated with risk (OR, 1.4; [1.0-2.0]). t-PA and PAI-1 levels predominantly reflected lipid levels, whereas plasminogen reflected the inflammatory state. Concluding, elevated alpha2-antiplasmin levels are independently associated with risk of myocardial infarction. t-PA, PAI-1, and plasminogen levels appear to reflect other cardiovascular risk factors.
The Way to Ultimate Meaning in Meister Eckhart’s Mysticism (1995)

Find information about UTP Journals. University of Toronto Press is Canada’s leading academic publisher and one of the largest university presses in North America, with particular strengths in the social sciences, humanities, and business. The Book Publishing Division is widely recognized in Canada for its strength in history, political science, sociology, Indigenous studies, and cultural studies. Internationally, UTP is a leading publisher of medieval, Renaissance, Italian, Iberian, Slavic, and urban studies, as well as studies in book and print culture.
Effects of imbalance on conducted immunity of a PLC link onto a DC power-bus for spacecraft (2015)

In this work, conducted-noise propagation in a Power Line Communications (PLC) link implemented on a spacecraft dc power-bus and involving differential signaling is investigated by resorting to modal analysis. The study mainly focuses on the detrimental effects on conducted immunity owing to the imbalance possibly introduced by the power units and the PLC modems. To this end, a suitable circuit interpretation of the propagation paths associated with common-mode (CM) and differential-mode (DM) components of the noise generated by the dc-dc converters is proposed, and the significant role that CM rejection properties of the modems play on immunity performance of the PLC link is outlined.
A segmentation-free approach for keyword search in historical typewritten documents (2005)

In this paper, we propose a novel segmentation-free approach for keyword search in historical typewritten documents combining image preprocessing, synthetic data creation, word spotting and user feedback technologies. Our aim is to search for keywords typed by the user in a large collection of digitized typewritten historical documents. The proposed method is based on: (i) image preprocessing for image binarization and enhancement, noisy border and frame removal, orientation and skew correction; (ii) creation of synthetic image words from keywords typed by the user; (Hi) word segmentation using dynamic parameters; (iv) efficient feature extraction for each image word and (v) a retrieval procedure that is optimized by user's feedback. Experimental results prove the efficiency of the proposed approach.
Strategies for Improving the Classroom Environment* (2001)

Abstract This paper describes some strategies for the educator seeking to better his/her classroom effectiveness. It was inspired by one of the technical sessions of the 29 th Annual IEEE/ASEE Frontiers in Education Conference in which over a dozen experienced college instructors engaged in a roundtable discussion of ways to improve a classroom environment. In this paper, those ideas are discussed and then supplemented with general advice and specific suggestions from the experience of the authors. The paper concludes with a bibliography of related reference material from a wide variety of educational sources.
Machine Learning for Vehicular Networks (2017)

The emerging vehicular networks are expected to make everyday vehicular operation safer, greener, and more efficient, and pave the path to autonomous driving in the advent of the fifth generation (5G) cellular system. Machine learning, as a major branch of artificial intelligence, has been recently applied to wireless networks to provide a data-driven approach to solve traditionally challenging problems. In this article, we review recent advances in applying machine learning in vehicular networks and attempt to bring more attention to this emerging area. After a brief overview of the major concept of machine learning, we present some application examples of machine learning in solving problems arising in vehicular networks. We finally discuss and highlight several open issues that warrant further research.
Analysis and optimization of sequential circuit element to combat single-event timing upsets (2010)

This paper presents the analysis and optimization of a flip-flop while considering the effect of energetic particle hits on its setup and hold times. First it is shown that the particle hit tightens the setup and hold timing constraints imposed on the flip-flop. Next it is shown how to size transistors of a clocked master-slave CMOS flip-flop to make it more robust against single-event timing upsets. Experimental results to assess the effectiveness of transistor sizing step are provided and discussed.
MEMS 2D matrix switch (2002)

Microelectromechanical systems, or MEMS, are among several promising technical approaches to implementing all-optical switching in telecom and data networks. At the core of MEMS switches is an array of micromirrors capable of redirecting light either in free space or within a waveguide framework. The 2D switch architecture as shown in figure I employs one mirror for every possible switched node in a matrix switch, and thus requires N/sup 2/ mirrors for an NXN array. 2D mirror arrays are characterized by two-state mirror positioning. One state is inactive and requires only that the mirror can be parked out of the optical path.
The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development (2017)

MicroRNAs (miRNAs) represent small noncoding RNAs that are involved in physiological and developmental processes by posttranscriptionally inhibiting gene expression. One of the largest miRNA clusters in mice is located in intron 10 of the Sfmbt2 gene, containing 72 miRNA precursor sequences. In this study, we generated mice lacking the entire Sfmbt2 miRNA cluster to elucidate its functions during development. The Sfmbt2 miRNAs were expressed predominantly from the paternal allele in the placenta, as is the host Sfmbt2 gene. Loss of the paternal allele resulted in severely impaired development of the placenta, especially the spongiotrophoblast layer, and frequent lethality or defects of fetuses. The predicted target sequences of the miRNAs and gene expression analysis defined at least nine putative target genes, which function as tumor suppressors or apoptosis inducers. Our study has provided experimental evidence for the indispensable roles of placental miRNAs in trophoblast proliferation and thus fetal development.
Off-centered spiral trajectories (2000)

The quality of spiral images depends on the accuracy of the k-space sampling locations. Although newer gradient systems can provide more accurate gradient waveforms, the sampling positions can be significantly distorted by timing misregistration between data acquisition and gradient systems. Even after the timing of data acquisition is tuned, minor residual errors can still cause shading artifacts which are problematic for quantitative MR applications such as phase-contrast flow quantitation. These timing errors can ideally be corrected by measuring the actual k-space trajectory, but trajectory measurement requires additional data acquisition and scan time. Therefore, off-centered spiral trajectories which are more robust against timing errors are proposed and applied to the phase-contrast method. The new trajectories turn shading artifacts into a slowly varying linear phase in reconstructed images without affecting the magnitude of images.
Direct detection of multiple backward volume modes in yttrium iron garnet at micron scale wavelengths (2019)

Using a set of wave-vector-specific multielement antennas, we have characterized the dispersion of spin waves in an yttrium iron garnet film at submicron lengths and resolved the dispersion relations of multiple backward volume modes, particularly in the region of their minima. The techniques developed now facilitate the characterization of spin waves at length scales limited only by available lithography and at a spectral resolution that generally exceeds that of Brillouin scattering. The data obtained are in excellent agreement with theoretical predictions based on a model Hamiltonian.
AVLS Using the Dedicated Wireless Communication between Vehicle and Road-Side Equipment (2000)

In this paper, we propose an AVLS(Automatic Vehicle Location System) using the DSRC(Dedicated Short Range Communication) which adopts a radio communication tool between RSE(Road-Side Equipment) and OBE(On-Board Equipment) on a vehicle and uses the ISM bandwidth of 5.8GHz radio frequency. Typical AVLS uses the sensors for detecting the vehicle, but the DSRC system is developed for supporting various services such as the position of vehicle, clearance, vehicle to vehicle communication, collection and distributions of traffic and road information. Also, for fast processing, we design three-layer configuration of physical(L1), data link(L2), and application layer(L7), which simplifies the seven-layer configuration. We suggest the proposed system as a new technology for replacement of typical wireless communication system and sensors for AVLS.
Bioinformatic design of A-kinase anchoring protein- <i>in silico</i> : A potent and selective peptide antagonist of type II protein kinase A anchoring (2003)

Compartmentalization of the cAMP-dependent protein kinase (PKA) is coordinated through association with A-kinase anchoring proteins (AKAPs). A defining characteristic of most AKAPs is a 14- to 18-aa sequence that binds to the regulatory subunits (RI or RII) of the kinase. Cellular delivery of peptides to these regions disrupts PKA anchoring and has been used to delineate a physiological role for AKAPs in the facilitation of certain cAMP-responsive events. Here, we describe a bioinformatic approach that yields an RII-selective peptide, called AKAP-in silico (AKAP-IS), that binds RII with a K(d) of 0.4 nM and binds RI with a K(d) of 277 nM. AKAP-IS associates with the type II PKA holoenzyme inside cells and displaces the kinase from natural anchoring sites. Electrophysiological recordings indicate that perfusion of AKAP-IS evokes a more rapid and complete attenuation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor currents than previously described anchoring inhibitor peptides. Thus, computer-based and peptide array screening approaches have generated a reagent that binds PKA with higher affinity than previously described AKAPs.
Three-dimensional passive circuit technology for ultra-compact MMICs (1995)

A novel passive circuit technology of a three-dimensional (3-D) metal-insulator structure is developed for ultra-compact MMICs. By combining vertical passive elements, such as a wall-like microwire for shielding or coupling, and a pillar-like via connection with multilayer passive circuits, a 3-D passive circuit structure is formed to implement highly dense and more functional MMICs. O/sub 2//He RIE for forming trenches and holes in a thick polyimide insulator, low-current electroplating for forming gold metal sidewalls in the trenches or holes, and ion-milling with a WSiN stopper layer for patterning the gold metal are used to produce such a structure. The complete 3-D structure provides miniature microstrip lines effectively shielded with a vertical metal-wall, a miniature balun with low-loss vertical wall-like microwires, and inverted microstrip lines jointed with pillar-like vias through a thick polyimide layer. This technology stages next-generation ultra-compact MMICs by producing various functional passive circuits in a very small area.
Lysate of Probiotic Lactobacillus casei DN-114 001 Ameliorates Colitis by Strengthening the Gut Barrier Function and Changing the Gut Microenvironment (2011)

Our study provided evidence that even non-living probiotic bacteria can prevent the development of severe forms of intestinal inflammation by strengthening the integrity of intestinal barrier and modulation of gut microenvironment.
SURF Tracking (2009)

Most motion-based tracking algorithms assume that objects undergo rigid motion, which is most likely disobeyed in real world. In this paper, we present a novel motion-based tracking framework which makes no such assumptions. Object is represented by a set of local invariant features, whose motions are observed by a feature correspondence process. A generative model is proposed to depict the relationship between local feature motions and object global motion, whose parameters are learned efficiently by an on-line EM algorithm. And the object global motion is estimated in term of maximum likelihood of observations. Then an updating mechanism is employed to adapt object representation. Experiments show that our framework is flexible and robust in dealing with appearance changes, background clutter, illumination changes and occlusion.
OPTICAL HAZE PROPERTIES OF POLYETHYLENE BLOWN FILMS: PART 1 - SURFACE VERSUS BULK STRUCTURAL CONSIDERATIONS a (2001)

In this paper we report on some recent findings regarding the factors affecting the optical (haze) properties of polyethylene (PE) blown films. An investigation of blown films made from representative conventional ZieglerNatta (Z-N) catalyzed linear low density PE (LLDPE) as well as metallocene-catalyzed LLDPE (mLLDPE) resins was conducted. It was found that the large majority of the contribution to the total haze in these blown films was a result of the surface roughness of the films, with the bulk (internal) contribution being relatively minor. Using atomic force microscopy (AFM) and small-angle light scattering (SALS) techniques, we found, quite unexpectedly, that the surface roughness in some of these films was a result of the development of distinct “spherulitic-like” superstructures formed during the blown film processing. These superstructures were observed only in the mLLDPE blown films, and not in the Z-N LLDPE blown films processed at similar conditions. In addition, we found that the haze of the blown films increased quite systematically with an increase in the degree of surface roughness i.e., an increase in the size of the “spherulitic-like” superstructures. Analysis of the rheological and molecular characteristics of these various mLLDPE and LLDPE resins revealed that the mLLDPE resins exhibited considerably lower molecular weight, narrower molecular weight distribution and lower melt elasticity compared to the LLDPE resins of similar melt index (MI). We therefore conclude that in blown films of LLDPE-type resins, the optical haze properties are adversely affected due to enhanced surface roughness caused by the formation of “spherulitic-like” superstructures in polymer melts that possess fast relaxing and low melt elasticity rheological characteristics.
Semiquantitative Visual Approach to Scoring Lung Cancer Treatment Response Using Computed Tomography (2009)

Using the SVS method, the readers more finely discriminated between the patient response categories with superior agreement compared with the RECIST method, which could potentially result in large differences in early treatment decisions for advanced lung cancer.
Effects of wireless physical layer modeling in mobile ad hoc networks (2001)

In most studies on mobile ad hoc networks (MANET), simulation models are used for the evaluation of devices and protocols. Typically, such simulations focus on the specific higher layer protocols that are being proposed, and tend to ignore details of models at other layers, particularly the interactions with physical layer models. In this paper, we present the set of factors at the physical layer that are relevant to the performance evaluations of higher layer protocols. Such factors include signal reception, path loss, fading, interference and noise computation, and preamble length. We start the discussion with the comparisions of physical layer models in ns-2 and GloMoSim, two commonly used simulators for MANET studies, and then quantify the impact of the preceding factors under typical scenarios used for the performance evaluation of wireless ad hoc routing protocols. Our experimental results show that the factors at the physical layer not only affect the absolute performance of a protocol, but because their impact on different protocols is non-uniform, it can even change the relative ranking among protocols for the same scenari
Big data through cross-platform interest-based interactivity (2014)

Given the ubiquity of social media, we capitalized on interest-based relevance as a key component to enhance user experience. Interest-based relevance modeling was extracted from user interaction in a cross-platform social media Big Data repository. The goal of this study was twofold: first we addressed theoretical dilemmas of a cross-platform user experience; second, we implemented an android-based mobile application and designed a cloud architecture to account for theoretical parameters of Big Data User-centric approach and interactivity. To address cross-platform Big Data challenges, we relied on cloud computing to perform computationally intensive operations such as searching, data mining, and data processing at large scale. Our use case was based on a cross-platform interest-based navigation and content filtering across multiple radio content streams. The streams consisted of tags from radio stations' programming and social media content through a discovery process. User interaction was geared to enable preferred topic filtering, flexibly shifting participation roles, notifications, and navigation through external data sources. We tested our application on a list of popular radio stations and their social media content streams (including Facebook, Twitter, Google+) to generate a Big Data scenario. Even if diverse and nature, data stream traffic generated through a mobile application KASU has proven to be a robust Big Data source with a list of ad hoc user-centric applications.
Polyketone materials: control of glass transition temperature and surface polarity by co‐ and terpolymerization of carbon monoxide with higher 1‐olefins (1997)

Abstract Highly soluble alternating 1‐olefin/carbon monoxide copolymers with olefin monomers (H 2 CCHR) containing 4, 5, 6, 10, 14, 16 and 18 C‐atoms in the R‐substituents were prepared by the use of dicationic palladium(II) phosphine catalysts and an optimized amount of methanol as activator. In terpolymerization experiments the influence of icosene‐CO or octadecene‐CO units, distributed randomly along a propene‐CO or ethene‐CO copolymer backbone, on molecular weight, glass transition temperature and on the surface polarity of films casted from solution has been investigated. As the length of the α‐olefin side chain increases, the glass transition temperature ( T g ) of the copolymer is reduced from room temperature to almost −60°C. For octadecene‐CO and icosene‐CO copolymers side chain crystallization occurs, leading to elastic materials. Contact angle measurements, performed on water drops located on the surface of selected co‐ and terpolymer films demonstrate the wide range of surface polarity which can be covered by simple copolymerization of polar CO groups with apolar alkenes.
A novel FcεRIβ‐chain truncation regulates human mast cell proliferation and survival (2010)

Mast cells contribute to allergy through IgE-dependent activation via the high-affinity IgE receptor FcεRI. The role of the FcεRIβ chain (MS4A2) in mast cell function is not understood fully, although it serves to amplify FcεRI-dependent signaling. We demonstrate the expression of a novel MS4A2 truncation lacking exon 3 in human mast cells termed MS4A2(trunc). MS4A2(trunc) gene expression was regulated negatively by the mast cell growth factor stem cell factor (SCF), and its expression was not detected in the SCF receptor gain-of-function human mast cell line HMC-1. Unlike MS4A2, MS4A2(trunc) did not traffic to the cytoplasmic membrane but instead was associated with the nuclear membrane. Overexpression of MS4A2(trunc) induced human lung mast cell death and profoundly inhibited HMC-1 cell proliferation by inducing G(2)-phase cell cycle arrest and apoptosis. Thus, we have identified a novel splice variant of MS4A2 that might be important in the regulation of human mast cell proliferation and survival. This finding demonstrates that the MS4A2 gene has multiple roles, extending beyond the regulation of acute allergic responses. By understanding the mechanisms regulating its function, it might be possible to induce its expression in mast cells in vivo, which could lead to better treatments for diseases such as mastocytosis and asthma.
In search for objective measures of hyperactivity, impulsivity and inattention in adult attention deficit hyperactivity disorder using the Quantified Behavior Test Plus (2011)

Clinical assessment tools for adult attention deficit hyperactivity disorder (ADHD) such as rating scales, interviews and behavior observations are often based on subjective judgments which enhance the risk of overlooking or misinterpreting symptoms. In search for objective measures of adult ADHD, the present study investigated levels of sensitivity and specificity for the Quantified Behavior Test Plus, QbTest-Plus, in adult patients (N = 19) awaiting clinical assessment for ADHD. QbTest-Plus report objective measures of ADHD core symptoms using an infrared motion tracking system and a continuous performance test. The measures were collected and evaluated previous to clinical assessment and compared regarding the diagnosis of ADHD. Sensitivity for detecting ADHD with QbTest-Plus was 83 % and specificity was 57 %. The results, possibly affected by confounding factors, suggest further examination of calibrated and objective measure for the QbTest-Plus with regard to ADHD in adults.