gebhart/patrepeval huggingface dataset:
Extracellular martix serum markers (ECMSM) in alcoholic liver disease. (1995)

In susceptible individuals, chronic alcoholic consumtion may lead to significant liver lesions which can progress to cirrhosis and death. Since liver biopsies cannot be frequently performed in the same patient to assess the evolution of liver disease, an evaluation of ECMSM, is noninvasive, easy to repeat and inexpensive and could play a role in the understanding of the mechanism of alcoholic fibrogenesis and fibrolysis, in the diagnosis of alcoholic liver disease and in the evaluation of upcoming antifibrotic treatments. Since the initial studies conducted with the first assay measuring aminoterminal propeptide of type III procollagen (PIIINP) in serum, other ECMSM have been evaluated in studies comparing only alcoholics to normal controls or including liver diseases of various origins.
Zero Point Energy, The Fuel of the Future (2007)

Preface Introduction to Zero Point Energy ZPE as an All-Pervading Electromagnetic Field What's All of That Noise and What Good is it? Zero Point Energy Can Supply Electricity Propulsion and Space Travel From ZPE How ZPE Products Will Affect Us Zero Point Field Consciousness Zero Point Energy Effects and Magic tricks The Science Behind the ZPE Effects Glossary.
Evolution of the Quadrantid meteor stream (1992)

According to previous orbital calculations, the last close approach of the Quadrantid stream with Jupiter occurred 3200 years ago at which time the parent comet of the stream may have been captured into its present short-period orbit. If this is the case the stream may only be a few thousand years old. We have modeled the evolution of the stream to determine if such a short time scale is consistent with the observed features of the Quadrantid/ delta- Aquarid/Arietid/Ursid complex. A detailed modeling of a stream consisting of 500 test particles released 4000 yr ago and which included the effects of the gravitational perturbations of 6 planets as well as the likely spread in the initial orbital elements resulting from the ejection of the grains from the comet was carried out. Our calculations indicate that an intense shower should be seen a few days before the Quadrantid shower, and that, 4000 yr is too short a period for the branch corresponding to the D-Arietid branch to appear. We have considered the quasi-constants of motion 1/a and J, the Tisserand quantity, and find that the Ursids and the D-Arietids are unlikely to be members of the complex, and that, the complex is probably be less than 4000 yr old.
Sexual segregation in winter, spring dispersal and habitat use in the pheasant (<i>Phasianus colchicus</i>) (1987)

Sexual segregation, spring dispersal and late winter to spring habitat selection were studied in the pheasant Phasianus colchicus L. on two areas for which the proportions of different habitats were similar. On one of the sites (Damerham) hand‐reared pheasants were released for shooting. On the other (Fulwell) no releasing or shooting took place. The sex ratio of birds feeding in fields in autumn favoured males because females fed in groups within woods. Groups of birds were significantly segregated by sex during early to late winter periods, but by late March they were not. Male groups and solitary males in winter were more evenly dispersed than female groups. At Fulwell, female winter groups consisted of regular group members (mainly adults) and transitory individuals called ‘drifters’ (mainly immatures). Females in their first breeding attempt dispersed further from their winter range to their breeding range than did adult females and females dispersed further than males. Males gaining a territory for the first time moved significantly further than old territory owners. Territorial males moved less than non‐territorial males between successive spring ranges. During March June, habitat use by 33 radio‐tagged females changed markedly from mixed and deciduous woodland to fields sown with winter and spring corn. The implications for management are outlined.
Accurate STR Allele Designations at the FGA and vWA Loci Despite Primer Site Polymorphisms (2004)

Polymerase chain reaction (PCR)-based STR DNA typing systems are used extensively in the field of human identification. Under optimal PCR conditions, the amplicon yield from both alleles of an STR locus is expected to be approximately equivalent. However, it is reasonable to expect that rare genomic sequence polymorphisms will co-localize with well-designed primer sets and induce allele imbalance or "dropouts". Two samples were identified in the course of genotyping thousands of individuals with AmpF/STR Profiler Plus that showed strong disparity in amplitude peak height of heterozygous peaks at the loci vWA and FGA. These samples were reamplified at reduced annealing temperature in an attempt to balance the peak heights. Nucleotide sequencing documented polymorphisms at the PCR primer binding sites of the affected alleles. The results indicate that reducing the annealing temperature to improve primer-binding efficiency at the mismatch and employing an alternative multiplex enhanced the data from both samples. Reducing annealing temperatures could provide a simple general solution to improving data quality for samples where polymorphisms are suspected to cause allele imbalance. Finally, we report on additional polymorphisms surrounding the vWA locus in a genetically diverse population.
Cisplatin-functionalized silica nanoparticles for cancer chemotherapy (2013)

Cisplatin is used to treat a variety of tumors, but dose-limiting toxicities or intrinsic and acquired resistance limit its application in many types of cancer including breast. Cisplatin was attached to silica nanoparticles using aminopropyltriethoxy silane as a linker molecule and characterized in terms of size, shape, as well as the dissolution of cisplatin from the silica surface. The primary particle diameter of the as received silica nanoparticles ranged from 20 to 90 nm. The results show that adverse effects on cell function, as evidenced by reduced metabolic activity measured by the MTT assay and increased membrane permeability observed using the live/dead stain, can be correlated with surface area of the silica. Cisplatin-functionalized silica nanoparticles with the highest surface area incited the greatest response, which was almost equivalent to that induced by free cisplatin. Moreover, if verified by further studies, would indicate that cisplatin was attached to silica nanoparticles might prove to be useful in site-specific drug delivery.
CRC (Cyclic Redundancy Check) Implementation in High-Speed Semiconductor Memory (2015)

This paper presents a CRC scheme for the semiconductor memory devices. Conventional error detecting method by using the ATM-8 HEC code leads to a considerable burden on the timing margin at the time of reading and writing of the low power memory devices for CRC(Cyclic Redundancy Check) calculations. The proposed error detecting scheme is improved area-overhead up to 92% and decreased 2 stage of XOR. The error detection coverage has improved compared with conventional method.
Heat Shock Pretreatment Prevents Cardiac Mitochondrial Dysfunction During Sepsis (2003)

The present study was designed to investigate the effect of previous heat shock treatment on the mitochondria function of the heart during a cecal ligation and puncture (CLP)-induced sepsis model. Rats of the heated group were heated by whole-body hyperthermia 24 h before the CLP operation. Cardiac mitochondria were freshly collected 9 and 18 h after CLP, indicating early and late sepsis, respectively. The expressions of heat shock protein 72 (Hsp72), glucose-regulated protein 75 (Grp75), and mitochondrial complexes I, II, III, and IV were evaluated by Western blot and immunochemical analysis. Enzyme activities of NADH cytochrome c reductase (NCCR), succinate cytochrome c reductase (SCCR), and cytochrome c oxidase (CCO) were measured after the reduction or oxidation of cytochrome c using a spectrophotometer. The results showed that the ATP content in the heart significantly declined during late sepsis, whereas heat shock treatment reversed this declination. The enzyme activities of NCCR, SCCR, and CCO were apparently suppressed during late stage of sepsis. The protein expressions of mitochondrial complex II and complex IV and Grp75 were also down-regulated during sepsis. Previously treated by heat shock, late-sepsis rats emerged with a high preservation of mitochondrial respiratory chain enzymes, both the protein amount and enzyme activity. Aspects of morphology were observed by electron microscopy, while heat shock treatment revealed the attenuation of cardiac mitochondrial damage induced by sepsis. In conclusion, structural deformity and the decrease of respiratory chain enzyme activity in mitochondria and its leading to a decline of ATP content are highly correlated with the deterioration of cardiac function during sepsis, and heat shock can reverse adverse effects, thus achieving a protective goal.
New Acid Etched Titanium Dental Implant Surface (2003)

Lietuvos sveikatos mokslų universitetas (302536989)
Accurate detection for process-hotspots with vias and incomplete specification (2007)

This paper introduces the concept of via range patterns and incompletely specified range patterns to represent new types of process-hotspots. Via range patterns can represent process-hotspots containing vias that are a major source of lithography issues. An incompletely specified range pattern can accurately and succinctly represent a process-hotspot where any configuration of objects (that is unknown to the user apriori) can exist in some of its peripheral regions. These new types of range patterns cannot be accurately represented and/or detected using the concept of range patterns introduced in [7]. A new detection algorithm that can accurately detect these new types of patterns is also proposed. This is necessitated since the range pattern matching algorithm proposed earlier causes mismatches: it either misses true matches or reports false matches for these new kinds of patterns. Theoretical results show that the proposed algorithm prevents the incorrect mis-match issues, while experimental results on fab provided process-hotspots show the algorithm is computationally efficient and practical for use on real industrial designs.
Advanced Optical Coherence Tomography techniques: novel and fast imaging tools for non-destructive testing (2012)

We demonstrate that Optical Coherence Tomography (OCT), a method which was originally developed for depth-resolved imaging of biological tissue, is suited to adequately respond to different problems posed in the field of contactless material characterisation and non-destructive testing and evaluation. In detail, the potential of advanced OCT techniques like ultrahigh-resolution OCT, polarisation-sensitive OCT or spectral-domain OCT is evaluated and exemplified for the imaging and characterisation of different polymer and ceramic materials, as well as of whole components, like polymer coated medical metal stents.
Haptotropic Migration from the Six- to the Five-Membered Ring of (3a,7a-Azaborindenyl)tricarbonylchromium Anion (2006)

The potassium salt of (η6-3a,7a-azaborindenyl)Cr(CO)3 was prepared in a THF solution at −60 °C. Warming to −40 °C causes the Cr(CO)3 group to undergo haptotropic migration to the five-membered ring. DFT calculations suggest that the preferred intramolecular pathway involves Cr(CO)3 coordination to the boron rather than the nitrogen side of the ligand.
ChemInform Abstract: PREPARATION AND THE CRYSTAL AND MOLECULAR STRUCTURE OF (NET4)(GE(CO2(CO)7)(CO2(CO)6(HGCO(CO)4)): AN ANION CONTAINING A MERCURY‐BRIDGED COBALT‐COBALT BOND (1981)

Abstract Die Reaktion von Gel4 mit Na[Co(CO)4] im Überschuß in Gegenwart von Hg ergibt das Anion der Titelverbindung, das als Et 4 N‐Salz (I) kristallin erhalten wird.
Drift-Flux Parameters for Three-Phase Steady-State Flow in Wellbores (2005)

Summary Drift-flux models represent multiphase flow in wellbores or pipes in terms of a number of empirically determined parameters. Because of the lack of data for two- and three-phase flow in large-diameter inclined pipes, existing parameters are commonly based on small-diameter pipe experiments, which can lead to significant errors when the models are applied to wellbore flows. In this work, we use recent large-diameter experimental data for the determination of drift-flux parameters for oil/water/gas flow. The parameters are computed through application of an optimization procedure. It is shown that in-situ gas volume fraction in three-phase systems can be estimated using a two-phase flow model by viewing the system as an effective gas/liquid system, with oil and water constituting the "liquid" phase. This approach is, however, generally inaccurate for the determination of oil and water holdups, in which case the effect of gas must be taken into account. Specifically, for pipe inclinations away from horizontal, even small amounts of gas can act to eliminate the slip between oil and water. As the pipe deviation approaches horizontal, however, oil/water slip persists, even in the presence of gas. We develop and apply a unified two-and three-phase flow model to capture this gas effect. The new model is shown to provide much more accurate predictions for oil and water holdups in three-phase systems than were achievable with previous models.
EUV lithography scanner for sub-8nm resolution (2015)

EUV lithography for resolutions below 8 nm half pitch requires the numerical aperture (NA) of the projection lens to be significantly larger than the current state-of-the-art 0.33NA. In order to be economically viable, a throughput in the range of 100 wafers per hour is needed. As a result of the increased NA, the incidence angles of the light rays at the mask increase significantly. Consequently the shadowing deteriorates the aerial image contrast to unacceptably low values at the current 4x magnification. The only solution to reduce the angular range at the mask is to increase the magnification. Simulations show that we have to double the magnification to 8x in order to overcome the shadowing effects. Assuming that the mask infrastructure will not change the mask form factor, this would inevitably lead to a field size that is a quarter of the field size of current 0.33NA step and scan systems. This would reduce the throughput of the high-NA scanner to a value significantly below 100 wafers per hour unless additional measures are taken. This paper presents an anamorphic step and scan system capable to print fields that are half the field size of the current full field. The anamorphic system has the potential to achieve a throughput in excess of 150 wafers per hour by increasing the transmission of the optics as well as increasing the acceleration of the wafer- and mask stage. This makes it an economically viable lithography solution. Furthermore, the simulated imaging behavior of the system is demonstrated and its impact on the rest of the lithographic system is discussed.
Enhanced light emission from an organic photonic crystal with a nanocavity (2005)

An organic photonic crystal (PC) with a nanocavity has been fabricated on a SiO2 membrane with air holes. The emission peak caused by the resonant mode of the nanocavity was clearly observed from the nanocavity area of the PC. The emission peak corresponded to degenerated dipole modes from comparison between measured and calculated results. Modification of a nanocavity caused the peak splitting of dipole modes and the appearance of a peak corresponding to a hexapole mode. The emission peak with a quality factor of about 1000 was obtained from a PC with a modified nanocavity.
Genetic Variants of Nogo-66 Receptor with Possible Association to Schizophrenia Block Myelin Inhibition of Axon Growth (2008)

In schizophrenia, genetic predisposition has been linked to chromosome 22q11 and myelin-specific genes are misexpressed in schizophrenia. Nogo-66 receptor 1 (NGR or RTN4R) has been considered to be a 22q11 candidate gene for schizophrenia susceptibility because it encodes an axonal protein that mediates myelin inhibition of axonal sprouting. Confirming previous studies, we found that variation at the NGR locus is associated with schizophrenia in a Caucasian case-control analysis, and this association is not attributed to population stratification. Within a limited set of schizophrenia-derived DNA samples, we identified several rare NGR nonconservative coding sequence variants. Neuronal cultures demonstrate that four different schizophrenia-derived NgR1 variants fail to transduce myelin signals into axon inhibition, and function as dominant negatives to disrupt endogenous NgR1. This provides the first evidence that certain disease-derived human NgR1 variants are dysfunctional proteins in vitro. Mice lacking NgR1 protein exhibit reduced working memory function, consistent with a potential endophenotype of schizophrenia. For a restricted subset of individuals diagnosed with schizophrenia, the expression of dysfunctional NGR variants may contribute to increased disease risk.
mRNA Localization by a 145-Nucleotide Region of the c-fos 3′- Untranslated Region (2001)

The presence of a localization signal in the 3'-untranslated region of c-fos mRNA was investigated by in situ hybridization and cell fractionation techniques. Cells were transfected with chimeric gene constructs in which the beta-globin coding region was used as a reporter and linked to either its own 3'-untranslated region, the c-fos 3'-untranslated region, or the c-fos 3'-untranslated region containing different deletions. Replacement of the endogenous beta-globin 3'-untranslated region by that from c-fos caused a redistribution of the transcripts so that they were recovered in cytoskeletal-bound polysomes and seen localized in the perinuclear cytoplasm. Deletion of the AU-rich instability region did not affect transcript localization, but removal of a distinct 145-nucleotide region of the 3'-untranslated region abolished it. The prevention of transcript translation by desferrioxamine led to a marked loss of transcript localization, independent of mRNA instability. The data show that the 3'-untranslated region of c-fos mRNA, as c-myc, contains a localization signal, which targets the mRNA to the perinuclear cytoskeleton. We propose that this is important to ensure efficient nuclear import of these key regulatory proteins. mRNA localization by the fos 3'-untranslated region is independent of mRNA instability, and the two are determined by different regulatory elements.
EXTRACORPOREAL PHOTOCHEMOTHERAPY AS SINGLE THERAPY FOR EXTENSIVE, CUTANEOUS, CHRONIC GRAFT-VERSUS-HOST DISEASE (1995)

Rossetti, Flavio; Zulian, Francesco; Dall'Amico, Roberto; Messina, Chiara; Montini, Giovanni; Zacchello, Franco Author Information
Peroxisome Proliferator-Activated Receptor δ Is an Essential Transcriptional Regulator for Mitochondrial Protection and Biogenesis in Adult Heart (2010)

PPARdelta is an essential regulator of cardiac mitochondrial protection and biogenesis and PPARdelta activation can be a potential therapeutic target for cardiac disorders.
Dipole moment differences of nonpolar dyes in polymeric matrices: Stark effect and photochemical hole burning. I (1992)

The difference of the induced dipole moments Δμind between the ground and excited state of (centro-)symmetric dye molecules (tetraphenylporphin and tetrapropylporphycene) embedded in different nonpolar and polar polymers is investigated. The technique of photochemical hole burning combined with Stark effect measurements was used to determine the values as a function of the burning frequency. For almost all systems an increase of Δμind from higher to lower optical frequencies was found. A plot of the &lt;Δμind≳ values measured at the absorption band maximum vs the low-temperature values of the dielectric constant ε shows a clear correlation between the dipole moment difference and the low-temperature ε values over the whole investigated range which is accessible with commercially available polymers. In order to evaluate the data the dielectric constant ε of each sample was determined in a series of separate experiments as a function of frequency and temperature.
Column fractionation of polymers. XXXI. Gel permeation chromatography. Mechanism of separation by flow (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTColumn fractionation of polymers. XXXI. Gel permeation chromatography. Mechanism of separation by flowSadao. Mori, Roger S. Porter, and Julian F. JohnsonCite this: Anal. Chem. 1974, 46, 11, 1599–1602Publication Date (Print):September 1, 1974Publication History Published online1 May 2002Published inissue 1 September 1974https://pubs.acs.org/doi/10.1021/ac60347a043https://doi.org/10.1021/ac60347a043research-articleACS PublicationsRequest reuse permissionsArticle Views81Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
UWB theory and applications (2004)

Introduction. UWB Channel Models. Modulation Schemes. Receiver Structures. Integrated Circuit Topologies. UWB Antennas. Medium Access Control. Positioning.
Geo-located image categorization and location recognition (2009)

Image categorization is undoubtedly one of the most recent and challenging problems faced in Computer Vision. The scientific literature is plenty of methods more or less efficient and dedicated to a specific class of images; further, commercial systems are also going to be advertised in the market. Nowadays, additional data can also be attached to the images, enriching its semantic interpretation beyond the pure appearance. This is the case of geo-location data that contain information about the geographical place where an image has been acquired. This data allow, if not require, a different management of the images, for instance, to the purpose of easy retrieval from a repository, or of identifying the geographical place of an unknown picture, given a geo-referenced image repository. This paper constitutes a first step in this sense, presenting a method for geo-referenced image categorization, and for the recognition of the geographical location of an image without such information available. The solutions presented are based on robust pattern recognition techniques, such as the probabilistic Latent Semantic Analysis, the Mean Shift clustering and the Support Vector Machines. Experiments have been carried out on a couple of geographical image databases: results are actually very promising, opening new interesting challenges and applications in this research field.