gebhart/patrepeval huggingface dataset:
Dynamic porelasticity: A unified theory with the Squirt and Biot mechanisms (1992)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1992Dynamic porelasticity: A unified theory with the Squirt and Biot mechanismsAuthors: Jack DvorkinAmos NurJack DvorkinStanford Univ. and Amos NurStanford Univ.https://doi.org/10.1190/1.1822168 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1822168FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1992ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1992 Pages: 1410 publication data© 1992 Copyright © 1992 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 10 Feb 2005 CITATION INFORMATION Jack Dvorkin and Amos Nur, (1992), "Dynamic porelasticity: A unified theory with the Squirt and Biot mechanisms," SEG Technical Program Expanded Abstracts : 620-623. https://doi.org/10.1190/1.1822168 Plain-Language Summary PDF DownloadLoading ...
Current status of Zika vaccine development: Zika vaccines advance into clinical evaluation (2018)

Zika virus (ZIKV), a mosquito-borne flavivirus, was first identified in the 1940s in Uganda in Africa and emerged in the Americas in Brazil in May 2015. In the 30 months since ZIKV emerged as a major public health problem, spectacular progress has been made with vaccine development cumulating with the publication of three reports of phase 1 clinical trials in the 4th quarter of 2017. Clinical trials involving candidate DNA and purified inactivated virus vaccines showed all were safe and well-tolerated in the small number of volunteers and all induced neutralizing antibodies, although these varied by vaccine candidate and dosing regimen. These results suggest that a Zika vaccine can be developed and that phase 2 clinical trials are warranted. However, it is difficult to compare the results from the different phase 1 studies or with neutralizing antibodies induced by licensed flavivirus vaccines (Japanese encephalitis, tick-borne encephalitis, and yellow fever) as neutralizing antibody assays vary and, unfortunately, there are no standards for Zika virus neutralizing antibodies. In addition to clinical studies, substantial progress continues to be made in nonclinical development, particularly in terms of the ability of candidate vaccines to protect reproductive tissues, and the potential use of monoclonal antibodies for passive prophylaxis.
Regulatory RNAs: Future Perspectives in Diagnosis, Prognosis, and Individualized Therapy (2006)

With potentially up to 1000 microRNAs (miRNAs) present in the human genome, altogether regulating the expression of thousands of genes, one can anticipate that miRNAs will play a significant role in health and disease. Deregulated protein expression induced by a dysfunctional miRNA-based regulatory system is thus expected to lead to the development of serious, if not lethal, genetic diseases. A relationship among miRNAs, Dicer, and cancer has recently been suggested. Further investigations will help establish specific causal links between dysfunctional miRNAs and diseases. miRNAs of foreign origin, e.g., viruses, may also be used as specific markers of viral infections. In these cases, miRNA expression profiles could represent a powerful diagnostic tool. Regulatory RNAs may also have therapeutic applications, by which disease-causing genes or viral miRNAs could be neutralized, or functional miRNAs be restored. Will bedside miRNA expression profiling eventually assist physicians in providing patients with accurate diagnosis, personalized therapy, and treatment outcome?
Hybridization <i>in vitro</i> of Subunits of the DNA‐Dependent RNA Polymerase from <i>Escherichia coli</i> and <i>Micrococcus luteus</i> (1975)

RNA polymerase core enzyme from the gram‐positive bacterium Micrococcus luteus is composed of three different types of subunits, very similar to the equivalent enzyme from the gram‐negative Escherichia coli although the overall net charge and the molecular size of the subunits is different. As in the E. coli enzyme the property of rifampicin resistance resides completely in the second largest subunit p. To investigate the functional correspondence of the subunits, intergeneric polymerase hybrids have been prepared in vitro from the isolated subunits. Active hybrids were obtained from mixtures of subunit α (from M. luteus ) with β and β′ (from E. coli ), of subunits α and β (from E. coli ) with β′ (from M. luteus ), of subunit α (from E. coli ) with β and β' (from M. luteus ), of subunit α and β′ (from M. luteus ) with β (from E. coli ). Rifampicin resistance and sensitivity of the hybrids containing subunit β from E. coli was solely determined by the resistance and sensitivity respectively of the E. coli RNA polymerase from which subunit β was isolated. The rate of formation of these hybrids is distinctly slower than the reconstitution of the parent E. coli RNA polymerase from subunits. The final activity reached during incubation is different for the various hybrids. All hybrids were able to transcribe natural and synthetic DNA and to catalyse the DNA‐directed synthesis of poly(A), whereas they were inactive in the de novo synthesis of poly(A) · poly(U) and poly(I‐C) · poly(I‐C) in contrast to the reconstituted E. coli enzyme. These results indicate a common structural and functional organization of bacterial RNA polymerases.
An industrial case study covering the use of IEC 1131-3 in connection with the engineering and operation requirements of the water industry (1999)

Bechtel have utilised or drawn upon many areas of the IEC 1131-3 standard during the design of their library of standard software modules (SSMs) starting with function block diagrams and sequential function blocks through to structured text and ladder diagram. The resulting library of SSMs that have been developed, sit together so successfully in a truly modular form that it is possible to replace an updated SSM within a configured and operational system without affecting any other section of the system. The software engineering techniques promoted in IEC 1131-3 have enabled Bechtel to implement the SSM approach across new projects and will now help to get away from the past where bespoke code was developed time and time again resulting in a different approach to the same problem of control, site by site. Bechtel's engineers and their contractors are now implementing this philosophy on a large number of key contracts with several water utilities to assess the success of the project. (4 pages)
Distributed Learning, Communication Complexity and Privacy (2012)

We consider the problem of PAC-learning from distributed data and analyze fundamental communication complexity questions involved. We provide general upper and lower bounds on the amount of communication needed to learn well, showing that in addition to VC-dimension and covering number, quantities such as the teaching-dimension and mistake-bound of a class play an important role. We also present tight results for a number of common concept classes including conjunctions, parity functions, and decision lists. For linear separators, we show that for non-concentrated distributions, we can use a version of the Perceptron algorithm to learn with much less communication than the number of updates given by the usual margin bound. We also show how boosting can be performed in a generic manner in the distributed setting to achieve communication with only logarithmic dependence on 1/epsilon for any concept class, and demonstrate how recent work on agnostic learning from class-conditional queries can be used to achieve low communication in agnostic settings as well. We additionally present an analysis of privacy, considering both differential privacy and a notion of distributional privacy that is especially appealing in this context.
A bacterial aromatic aldehyde dehydrogenase critical for the efficient catabolism of syringaldehyde (2017)

Vanillin and syringaldehyde obtained from lignin are essential intermediates for the production of basic chemicals using microbial cell factories. However, in contrast to vanillin, the microbial conversion of syringaldehyde is poorly understood. Here, we identified an aromatic aldehyde dehydrogenase (ALDH) gene responsible for syringaldehyde catabolism from 20 putative ALDH genes of Sphingobium sp. strain SYK-6. All these genes were expressed in Escherichia coli, and nine gene products, including previously characterized BzaA, BzaB, and vanillin dehydrogenase (LigV), exhibited oxidation activities for syringaldehyde to produce syringate. Among these genes, SLG_28320 (desV) and ligV were most highly and constitutively transcribed in the SYK-6 cells. Disruption of desV in SYK-6 resulted in a significant reduction in growth on syringaldehyde and in syringaldehyde oxidation activity. Furthermore, a desV ligV double mutant almost completely lost its ability to grow on syringaldehyde. Purified DesV showed similar k<sub>cat</sub>/K<sub>m</sub> values for syringaldehyde (2100 s<sup>-1</sup>·mM<sup>-1</sup>) and vanillin (1700 s<sup>-1</sup>·mM<sup>-1</sup>), whereas LigV substantially preferred vanillin (8800 s<sup>-1</sup>·mM<sup>-1</sup>) over syringaldehyde (1.4 s<sup>-1</sup>·mM<sup>-1</sup>). These results clearly demonstrate that desV plays a major role in syringaldehyde catabolism. Phylogenetic analyses showed that DesV-like ALDHs formed a distinct phylogenetic cluster separated from the vanillin dehydrogenase cluster.
Effects of <i>Pinus pinaster</i> and <i>Pinus koraiensis</i> seed oil supplementation on lipoprotein metabolism in the rat (1999)

The aim of the present study was to assess the effect of vegetal oils obtained from Pinus pinaster and P. koraiensis seeds on plasma lipoprotein levels and apolipoprotein (apo) gene expression in rats. These oils contain two particular fatty acids of the delta5-unsaturated polymethylene-interrupted fatty acid (delta5-UPIFA) family: all-cis-5,9,12-1 8:3 (pinolenic) and/or all-cis-5,11,14-20:3 (sciadonic) acids. Rats were fed for 28 d a diet containing 5% (w/w) oil supplement. Two control diets were prepared to match the fatty acid composition of P. pinaster or P. koraiensis oils with the exception of delta5-UPIFA, which were replaced by oleic acid. Pinus pinaster seed oil decreased serum triglycerides by 30% (P < 0.02), very low density lipoprotein (VLDL)-triglycerides by 40% (P < 0.01), and VLDL-cholesterol by 33% (P < 0.03). Pinus koraiensis seed oil decreased serum triglycerides by 16% [not statistically significant (ns)] and VLDL-triglycerides by 21% (ns). Gel permeation chromatography and nondenaturating polyacrylamide gel electrophoresis showed a tendency of high density lipoprotein to shift toward larger particles in pine seed oil-supplemented rats. Finally, P. pinaster seed oil treatment was associated with a small decrease of liver apoC-III (P < 0.02) but not in apoE, apoA-I, or apoA-II mRNA levels. The levels of circulating apo were not affected by pine seed oil supplementation. In conclusion, P. pinaster seed oil has a triglyceride-lowering effect in rats, an effect that is due to a reduction in circulating VLDL.
Should international law be codified? And if so, should it be done through governmental agencies or by private scientific societies? (1915)

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Zur Kenntnis der Proanthocyanidine, X Procyanidine aus Früchten (1968)

Abstract Die von uns aus Früchten isolierten Procyanidine zerfallen beim Erwärmen mit Säuren in Cyanidin und Catechin bzw. Epicatechin. Sie sind demnach als dimere Flavonoide mit einem Kohlenstoffgerüst von 30 C‐Atomen aufzufassen. Nach der Anzahl der Wasserstoffatome werden sie in zwei Gruppen der Summenformel C 30 H 26 O 12 (Gruppe B ) und C 30 H 24 O 12 (Gruppe A) eingeteilt. Innerhalb dieser Gruppen sind sowohl Struktur‐ als auch Stereoisomere denkbar. Die Konstitutionen der beiden Procyanidin‐Gruppen werden an Hand NMR‐ und massenspektrometrischer Untersuchungen ihrer Derivate diskutiert. Zum Vergleich wurden Modellsubstanzen synthetisiert.
Comments on "A Two's Complement Parallel Array Multiplication Algorithm" (1974)

This correspondence presents a simpler proof for Baugh and Wooley's two's complement parallel array multiplication algorithm, as demonstrated in a recent paper.1 The above algorithm converts a two's complement multiplication to an equivalent parallel array addition problem in which all partial product bits are positive.
Epidemic Population Structure of <i>Pseudomonas aeruginosa</i> : Evidence for a Clone That Is Pathogenic to the Eye and That Has a Distinct Combination of Virulence Factors (2001)

The genetic structure of a population of Pseudomonas aeruginosa, isolated from patients with keratitis, endophthalmitis, and contact lens-associated red eye, contact lens storage cases, urine, ear, blood, lungs, wounds, feces, and the environment was determined by multilocus enzyme electrophoresis. The presence and characteristics of virulence factors were determined by restriction fragment length polymorphism analysis with DNA probes for lasA, lasB, aprA, exoS, exoT, exoU, and ctx and by zymography of staphylolysin, elastase, and alkaline protease. These analyses revealed an epidemic population structure of P. aeruginosa, characterized by frequent recombination in which a particular successful clone may increase, predominate for a time, and then disappear as a result of recombination. Epidemic clones were found among isolates from patients with keratitis. They were characterized by high activity of a hitherto-unrecognized size variant of elastase, high alkaline protease activity, and possession of the exoU gene encoding the cytotoxic exoenzyme U. These virulence determinants are not exclusive traits in strains causing keratitis, as strains with other properties may cause keratitis in the presence of predisposing conditions. There were no uniform patterns of characteristics of isolates from other types of infection; however, all strains from urinary tract infections possessed the exoS gene, all strains from environment and feces and the major part of keratitis and wound isolates exhibited high elastase and alkaline protease activity, and all strains from feces showed high staphylolysin activity, indicating that these virulence factors may be important in the pathogenesis of these infectious diseases.
Vehicle Speed Detection and Identification from a Single Motion Blurred Image (2005)

Motion blur is a result of finite acquisition time of practical cameras and the relative motion between the camera and moving objects. Traditionally, the image degradations caused by motion blur are treated as undesirable artifacts and usually have to be removed before further processing. In this work, we propose a novel approach for vehicle speed detection based on a single motion blurred image as opposed to the most commonly used RADAR and LIDAR devices for traffic law enforcement. The motion blur parameters are estimated from a single motion blurred image and the length of motion blur is used for image restoration. The restored image is then used to obtain other parameters for vehicle speed estimation. The images taken with the vehicle's license plates are used for both the assistance of image restoration and the identification of the vehicle. We have established a link between the motion blur information of a 2D image and the speed information of a moving object. Experiments have shown the results of less than 2% error for both local and highway traffic compared to video-based speed estimation methods
The National Severe Storms Laboratory Tornado Detection Algorithm (1998)

The National Severe Storms Laboratory (NSSL) has developed and tested a tornado detection algorithm (NSSL TDA) that has been designed to identify the locally intense vortices associated with tornadoes using the WSR-88D base velocity data. The NSSL TDA is an improvement over the current Weather Surveillance Radar-1988 Doppler (WSR-88D) Tornadic Vortex Signature Algorithm (88D TVS). The NSSL TDA has been designed to address the relatively low probability of detection (POD) of the 88D TVS algorithm without a high false alarm rate (FAR). Using an independent dataset consisting of 31 tornadoes, the NSSL TDA has a POD of 43%, FAR of 48%, critical success index (CSI) = 31%, and a Heidke skill score (HSS) of 46% compared to the 88D TVS, which has a POD of 3%, FAR of 0%, CSI of 3%, and HSS of 0%. In contrast to the 88D TVS, the NSSL TDA identifies tornadic vortices by 1) searching for strong shear between velocity gates that are azimuthally adjacent and constant in range, and 2) not requiring the presence of an algorithm-identified mesocyclone. This manuscript discusses the differences between the NSSL TDA and the 88D TVS and presents a performance comparison between the two algorithms. Strengths and weaknesses of the NSSL TDA and NSSL's future work related to tornado identification using Doppler radar are also discussed.
PREDETERMINATION BY INFECTION AND BY VACCINATION OF ANTIBODY RESPONSE TO INFLUENZA VIRUS VACCINES (1957)

The antibody orienting effects of prior infections with antigenic variants of influenza viruses were confirmed by studies with monovalent adjuvant vaccines and with polyvalent aqueous and adjuvant preparations. In either case, the predominant antibody response was of a "booster" type, directed against the major antigens of strains of original infection. It was shown that vaccination with appropriate strains, selected as antigenic prototypes, could orient or predetermine subsequent antibody response upon revaccination. Moreover, the effects of exposure by vaccination were found to be durable and to constitute a foundation upon which future antibody dividends could be accumulated. As a result, it seems feasible to induce by vaccination a more lasting broad composite antibody protection against influenza if appropriate preparations and schedules are used.
40nm & 22nm Embedded Charge Trap Flash for Automotive Applications (2018)

Key attributes of Embedded Charge Trap (eCTTM) Flash technology are presented. Automotive MCUs with 40nm eCT Flash are currently in volume production at UMC. The eCT technology features industry-leading cell size at the 40nm node, and scaling by more than 30% has been demonstrated at the 22nm node. eCT utilizes source-side injection (SSI) for programming and band-to-band (BTB) hot- hole injection for erasing to meet the high-speed requirements of automotive applications. Furthermore, random access time of 8 ns is achieved across the full range of operational temperature (-40 °C to 150 °C) and voltage (0.99 V to 1.21 V).
Analysis and synthesis of UHF RFID antennas using the embedded T-match (2010)

The T-match structure is commonly used to match an RFID chip's reactive impedance to a dipole. Models that describe T-match are known, but they are neither sufficiently accurate to model antennas nor to synthesize the antenna geometry. Here, we present the embedded T-match circuit model, which is amenable to accurate analysis and synthesis.
Isocyanates of 3,4-Benzpyrene and 10-Methyl-1,2-benzanthracene (1941)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsocyanates of 3,4-Benzpyrene and 10-Methyl-1,2-benzanthraceneHugh J. CreechCite this: J. Am. Chem. Soc. 1941, 63, 2, 576–578Publication Date (Print):February 1, 1941Publication History Published online1 May 2002Published inissue 1 February 1941https://pubs.acs.org/doi/10.1021/ja01847a062https://doi.org/10.1021/ja01847a062research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Interferon blocks interleukin 1-induced prostaglandin release from human peripheral monocytes. (1987)

We have studied the short-term effects of interleukin 1, lipopolysaccharide, and interferon on prostaglandin release from freshly isolated human peripheral monocytes. When the cells were pretreated for 8 to 9 hr with either E. coli lipopolysaccharide or recombinant interleukin 1 (beta), prostaglandin release increased. Inclusion of recombinant IFN-alpha or IFN-gamma during the pretreatment phase blocked subsequent prostaglandin release. Interferons were effective at concentrations in the range of 1 to 10 antiviral units/ml, and the inhibition was manifested within several hours after exposure to the lymphokine. Similar trends were observed by measuring thromboxane release. These data suggest antagonistic roles for interleukin 1 and interferon in the regulation of eicosanoid release from monocytes.
BISMO: A Scalable Bit-Serial Matrix Multiplication Overlay for Reconfigurable Computing (2018)

Matrix-matrix multiplication is a key computational kernel for numerous applications in science and engineering, with ample parallelism and data locality that lends itself well to high-performance implementations. Many matrix multiplication-dependent applications can use reduced-precision integer or fixed-point representations to increase their performance and energy efficiency while still offering adequate quality of results. However, precision requirements may vary between different application phases or depend on input data, rendering constant-precision solutions ineffective. We present BISMO, a vectorized bit-serial matrix multiplication overlay for reconfigurable computing. BISMO utilizes the excellent binary-operation performance of FPGAs to offer a matrix multiplication performance that scales with required precision and parallelism. We characterize the resource usage and performance of BISMO across a range of parameters to build a hardware cost model, and demonstrate a peak performance of 6.5 TOPS on the Xilinx PYNQ-Z1 board.
An adaptive input shaping control scheme for vibration suppression in slewing flexible structures (1993)

The application of an input precompensation scheme for vibration suppression in slewing flexible structures, with particular application to flexible-link robotic manipulator systems, is considered. The control from such input shaping schemes corresponds to a feedforward term that convolves in real time the desired reference input with a sequence of impulses and produces a vibration-free output. The robustness of such an algorithm with respect to modal frequency variations is not satisfactory but can be improved by convolving the input with a longer sequence of impulses, the tradeoff being a decrease in the transient response speed. An adaptive precompensation scheme that can be implemented by combining a frequency domain identification scheme, used to estimate the modal frequencies online, with a subsequent scheme for adjusting the spacing between the impulses is proposed. The combined adaptive input shaping scheme provides the most rapid slew that results in a vibration-free output. Experimental results for a single flexible link are presented to verify the technique.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>