gebhart/patrepeval huggingface dataset:
A New Concept of Sand Management Philosophy; Revolutionary & Cost Effective Solution (2017)

Abstract In the current oil price environment, all new developments are pursued with minimum capital investment and lowest possible operating cost to improve project economics. Projects that do not meet the economic criteria have to be shelved or deferred to a later date. This was the case for a green gas field development in Peninsular Malaysia which was shelved in 2016, resulting in an added preservation requirement for the newly-fabricated topside facilities and pipelines. The increase in project cost due to the preservation requirements, eroded the project economics which necessitates all possible cost reductions in order to make the overall project economically viable. One possible area for cost reduction is the sand management. Sand production is expected from the shallower I-group reservoirs targeted in the gas development. This is based on well test results conducted in one of the appraisal wells which is further supported by a sand production prediction (SPP) study. Based on the available Particle Size Distribution (PSD) data from a Laser Particle Sieve Analysis (LPSA), the reservoir particle D50 is about 55µm and has more than 40% fines content. Due to the multilayer reservoir targets, cased hole development were designed for the well hence Internal Gravel pack (IGP) is selected as the downhole sand exclusion method. Over the life of the field, fines production is anticipated due to the high fines content of the reservoir. There is also risk of IGP failure which could result in eroded tubings, flowlines and headers. This would be catasthropic for the green field due to its unmanned operation philosophy. Moreover, during the facilities detailed design, the provision for surface desander was eliminated to make way for a compact platform design. This paper will describe the methodology used to assess the severity of sand production to the surface facilities using the well and reservoir parameters. The assessment results provide the basis for the field integrated sand management philosophy, which helps management to make an informed decision to eliminate the real time sand monitoring and control system requirements and also eliminate the need for platform deck extension for desander installation requirement.
Assessment of Thin Thermal Barrier Coatings for I.C. Engines (1995)

<div class="htmlview paragraph">This paper investigates theoretically the effects of heat transfer characteristics, such as crank-angle phasing and wall temperature swings, on the thermodynamic efficiency of an IC engine. The objective is to illustrate the fundamental physical basis of applying thin thermal barrier coatings to improve the performance of military and commercial IC engines. A simple model illustrates how the thermal impedance and thickness of coatings can be manipulated to control heat transfer and limit the high temperatures in engine components. A friction model is also included to estimate the overall improvement in engine efficiency by the proper selection of coating thickness and material.</div>
Mechanism of translocation. Binding equilibria between the ribosome, mRNA analogues, and cognate tRNAs. (1982)

The translocation of the mRNA in relation to the ribosome during peptide synthesis represents an example for a mechanochemical reaction in which the chemical bond energy of GTP is transformed into coordinated motion. We demonstrate here that translocation can be explained simply by binding equilibria between the tRNA, the mRNA, and their binding sites on the ribosome. The presence of two cognate tRNAs shifts the association constant for the 70 S ribosome . AUGU3 complex from 6.8 x 10(5) to 2.2 x 10(8) M-1. The elongation factor G and GTP or guanosine-5'-(beta,gamma-methylene)triphosphate GMP-PCP) displace the methionine tRNAs which can be formylated (tRNAfMet) from the quaternary complex 70 S . AUGU3 . tRNAfMet . tRNAPhe. Only the ternary complex Phe-tRNAPhe . elongation factor Tu . GMP-PCP shows an absolute preference for the aminoacyl-tRNA binding site (A site) (K a = 6.6 x 10(6) M-1). AcPhe-tRNAPhe, (N alpha-acetylphenylalanyl-tRNA) an analogue of a peptidyl-tRNA exhibits a 20-fold higher affinity to the peptidyl-tRNA binding site (P site) (K a = 3.5 x 10(6) M-1) as against the A site (K a = 1.8 x 10(6) M-1) at 8 mM Mg2+. Compared to aminoacyl-tRNA and tRNA, peptidyl-tRNA shows a 3- to 15-fold higher affinity toward complementary oligonucleotides both in the binary complex and in the presence of 70 S ribosomes (UUCA . AcPhe-tRNAPhe: K a = 1.9 x 10(5) M-1), UUCA . tRNAPhe:K a = 3.2 x 10(4) M-1). This indicates a stabilization of the peptidyl-tRNA . mRNA complex during translocation. Our data support a concept of mRNA translocation in which the removal of the deacylated tRNA from the P site requires GTP energy and a peptidyl-tRNA . mRNA complex diffuses from its low affinity site (A) to its high affinity binding site (P).
Oxadiazole-Triphenylamine derivatives for OLEDs (2005)

Electroluminescent bipolar small molecules have been attracted with great interests recently. They are found to exhibit many interesting features such as (i) reducing the structural complexity of organic light emitting diodes (OLEDs) from multilayer heterojunction to monolayer homojunction devices; (ii) offering molecular p/n junction, and (iii) minimizing the formation of exciplexes. In this paper, the optical and electrical properties of novel oxadiazole-triphenylamine derivatives will be investigated. The derivatives are N-phenyl-N-(4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl)phenylamine (POT) and N-phenyl-N-(4-(5-p-tolyl-1,3,4-oxadiazol-2-yl)phenyl)phenylamine (m-POT). The absolute absorption coefficient and refractive index have been investigated by ellipsometry and modeling. The electron mobility of POT at room temperature has been studied. The results show that the derivatives have bipolar characteristics. The electron-transporting properties of POT is better than that of m-POT. The EL emission peaks of POT and m-POT are the same at 435nm which match with their photoluminescent (PL) peaks.
RF ablation at audio frequencies preferentially targets tumor - a finite element study (2002)

Radio Frequency (RF) ablation has become of considerable interest as a minimally invasive treatment for primary and metastatic liver tumors. Major limitations are small lesion size, which make multiple applications necessary and incomplete killing of tumor cells, resulting in high recurrence rates. RF ablation is typically carried out in the frequency range of around 500 kHz. Measurements have shown a marked difference in electrical conductivity between normal liver tissue and tumor tissue. The difference is most pronounced at frequencies below 100 kHz, where tumors exhibit around two times higher conductivity compared to normal tissue. Conductivity is similar for tumor and normal liver at 500 kHz. We created Finite Element Method (FEM) models of the RITA model-30 multi-prong probe. The probe was placed in a tumor of 20 mm diameter. We simulated 12 minute, temperature controlled RF ablation at 95/spl deg/C at frequencies of 20 kHz and 500 kHz. At 20 kHz we observed increased current density within the tumor boundaries. This resulted in an increase in lesion size by 29% at a frequency of 20 kHz compared to 500 kHz.
(Invited) A Brief Review of Doping Issues in III-V Semiconductors (2013)

A brief review of n-type doping of GaAs, InGaAs and InP using ion implantation is presented. While the diffusion of the amphoteric dopant Si is not a significant issue its activation is limited to around 1×10 19 /cm 3 . This has prompted many studies into factors that might affect dopant activation including co-implantation to force site selection, damage and amorphization effects, elevated temperature implants and capping effects. A summary of these results is discussed. With interest in using III-V materials for n-channel devices in future sub 15 nm devices there is also an increasing interest in low energy implants. This suggests the role of surface degradation upon annealing will become even more important. Recent results along these lines are presented.
Noncyclic crown-type polyethers, pyridinophane cryptands, and their alkali metal ion complexes: synthesis, complex stability, and kinetics (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNoncyclic crown-type polyethers, pyridinophane cryptands, and their alkali metal ion complexes: synthesis, complex stability, and kineticsBurkhard Tuemmler, Guenter Maass, Edwin Weber, Winfried Wehner, and Fritz VoegtleCite this: J. Am. Chem. Soc. 1977, 99, 14, 4683–4690Publication Date (Print):June 1, 1977Publication History Published online1 May 2002Published inissue 1 June 1977https://pubs.acs.org/doi/10.1021/ja00456a026https://doi.org/10.1021/ja00456a026research-articleACS PublicationsRequest reuse permissionsArticle Views613Altmetric-Citations159LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Guinea Pig Membrane-Bound Aminopeptidase P Is a Member of the Proline Peptidase Family (1994)

Members of the newly recognized proline peptidase family share the ability to hydrolyze imide bonds and share six blocks of highly homologous amino acid sequences. We have found that guinea pig lung and kidney forms of aminopeptidase P, both forms bound to membranes via glycosyl phosphatidylinositol lipid anchors, share at least three of the six conserved blocks of amino acid sequences. In addition, aminopeptidase P acts as an aminoacylproline hydrolase and thus appears to be a member of the proline peptidase family.
Dielectric breakdown in nonuniform field air gaps (1993)

The sparkover characteristics of rod-rod and rod-plane gaps in air under DC voltages are reviewed. The linear characteristics of both configurations are associated with the prominence of streamer discharges during the prebreakdown phase. The limits of linearity are shown to be a function of humidity, gap spacing and electrode profile, all of which determine the predischarge mode. It is shown that the rod-plane gap offers a wider range of linearity than the rod-rod gap and that it can have a valid role as a DC voltage measurement tool.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Those allegations most vile (2002)

Anti-L523S antibody is a useful marker for the detection of malignant cells in serous effusions and it can have significant utility in differentiating reactive mesothelial cells from malignant mesothelioma and metastatic carcinoma in combination with calretinin and CK5/6 staining.
A First Principles Battery Model for the International Space Station (2005)

*† The International Space Station (ISS) program uses an empirical model to predict battery voltage performance. The data consist of cell voltage versus time at constant current, at beginning and end of life, for three depths of discharge (20%, 35%, 60%), and three temperatures (0, 10, 20C). Battery voltage is calculated from current, temperature, life fraction, and depth of discharge. It has been suggested that by using a first principles based model the accuracy of battery voltage predictions would improve over those achieved by empirical models. The accuracy of voltage predictions is of great importance to the ISS program because it is only via simulations that it can be determined whether operations can go forward as planned or should be modified to maintain sufficient battery voltage levels. To test this idea we first developed a general model based on the fundamental dynamic behavior of the battery, relying on Faraday’s Law and the Butler-Volmer equation. Next, the model was optimized using on-orbit ISS reconditioning data from late 2004 and early 2005. Last, the model was tested against normal ISS cycling telemetry using battery current and initial state of charge as inputs. Results show that this first principles model can reduce the error in battery voltage prediction when compared to the standard empirical model. We conclude that by modeling stored and diffusing charge, and the electrode, voltage behavior can be predicted satisfactorily. In addition, modeling different resistances in charge and discharge improves predictions. Finally, modeling the batteries at the individual cell level or half battery level did not result in marked improvement of voltage predictions over modeling the entire battery as a whole. In general, accuracy is limited by insight into battery characteristics, such as capacity. The techniques used here for nickel-hydrogen chemistry in particular have been applied to other battery chemistries.
Should PUVA Be Abandoned? (1997)

Severe, widespread psoriasis is a devastating skin disease that can disrupt professional, social, and private life. The effectiveness of photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA)1 in inducing and maintaining the remission of severe psoriasis has been amply documented1,2 and confirmed in large-scale cooperative clinical trials in both the United States3 and Europe.4 PUVA induces remission of psoriasis through repeated, controlled phototoxic reactions that occur only when psoralens are photoactivated by ultraviolet A. Neither the drug nor ultraviolet A is effective alone.5 Given the penetration characteristics of ultraviolet A, the absorption of photons is confined to . . .
Monolithically integrated laser/Mach-Zehnder modulators using quantum wells (2002)

We demonstrate monolithic integration of a DBR laser with an interferometric waveguide intensity modulator. Individually-tailored multiple quantum well regions provide gain and enhanced electrofraction to achieve extreme compactness and low drive voltage requirements.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Clinical efficacy of TNF-α inhibitors: an update (2010)

Over the last decade, TNF-α antagonists became the most powerful tools for controlling patient suffering from a number of rheumatic diseases. Infliximab, etanercept and adalimumab can induce remission and prevent both clinical and radiological disease progression in rheumatoid arthritis with significant improvement in patients’ symptoms, function and quality of life. They improve joint symptoms and significantly retard radiographic progression in psoriatic arthritis. TNF-α antagonists have been demonstrated to reduce disease activity, retard radiologic progression and increase quality of life in ankylosing spondylitis patients. Long-term follow-up studies demonstrated sustained efficacy and acceptable safety profiles that were comparable in rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis. Etanercept is the only US FDA-approved TNF antagonist for juvenile rheumatoid arthritis. TNF-α antagonists may improve some clinical manifastations of Behcet’s disases, including uveitis. Tuberculosi...
Using twitter to recommend real-time topical news (2009)

Recommending news stories to users, based on their preferences, has long been a favourite domain for recommender systems research. In this paper, we describe a novel approach to news recommendation that harnesses real-time micro-blogging activity, from a service such as Twitter, as the basis for promoting news stories from a user's favourite RSS feeds. A preliminary evaluation is carried out on an implementation of this technique that shows promising results.
Single-beam photothermal microscopy: a new diagnostic tool for optical materials (1999)

A novel photothermal microscopy (PTM) is developed which uses only one laser beam, working as both the pump and the probe. The principle of this single-beam PTM is based on the detection of the second harmonic component of the laser modulated scattering (LMS) signal. This component has a linear dependence on the optical absorptance of the tested area and a quadratic dependence on the pump laser power. Using a pump laser at the wavelengths of 514.5- and 532-nm high-resolution photothermal scans are performed for polished fused silica surfaces and a HfO<SUB>2</SUB>/SiO<SUB>2</SUB> multilayer coatings. The results are compared with those from the traditional two-beam PTM mapping. It is demonstrated that the single-beam PTM is more user-friendly than conventional two-beam PTM and, offers a higher spatial resolution for defect detection.
Water-Soluble Porphyrin-Polyethylene Glycol Conjugates with Enhanced Cellular Uptake for Photodynamic Therapy (2009)

Water soluble porphyrins were designed and prepared by Williamson ether synthesis reaction between tetrakis(p-bromomethylphenyl)porphyrin and polyethylene glycol (PEG) for photodynamic therapy. The quantum yields for the generation of singlet oxygen of tetra-polyethylene glycol branched porphyrin shows above 80% in D2O. Luminescence of singlet state oxygen was observed from D2O solution under the single-photon excitation at 514 nm. In vitro test, cellular uptake efficiency has been enhanced by simple modification of molecular structure through changing the number of PEG unit without any support such as polymer-encapsulated inorganic nanoparticles.
Frequency-temperature considerations for digital temperature compensation (2002)

A fundamental requirement for compensation of the frequency-temperature (F-T) characteristics of a resonator is that the scheme used to estimate the frequency of the resonator from the temperature measurement be able to provide the necessary precision. A description is given of the anomalous behavior of the (F-T) characteristics of quartz resonators at the pp 10/sup 8/ level, which necessitates a sophisticated estimation scheme. Estimation schemes, including least squares regression, minmax, segmented polynomials, and interpolation algorithms such as spline and Akima, are reviewed. There are many choices for (F-T) compensation algorithms which are superior to the usual least squares fit. These algorithms can be used with any digital compensation technique. The multisegment Lawson algorithm is the most efficient choice, but any of the interpolation schemes will give optimum results at the cost of requiring more memory.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Nuevas alternativas al control de compactación en rellenos y explanadas (2012)

Of the 100,000-plus valve surgeries performed each year in the United States, up to 6% of those develop complications from prosthetic valve dysfunction. Prosthetic valve dysfunction (PVD) can be life threatening and often challenging to diagnose. In this review, we discuss the prevalence and incidence of PVD, explore its different etiologies, and assess the role of multimodality imaging with an emphasis on cardiac multidetector computed tomography (MDCT) for evaluating patients with PVD. We also investigate the utility of MDCT in preprocedural planning for transcatheter devices and redo surgical planning and discuss management strategies for patients with PVD.
Detection and Function of Opioid Receptors on Cells from the Immune System (2000)

Opioid alkaloids and peptides, such as morphine and the endogenous opioid peptides, including β-endorphin and the dynorphin peptides, modulate the function of lymphocytes and other cells involved in host defense and immunity. In recent years, investigations from several laboratories have indicated
Structural analyses of fibrinogen amyloid fibrils (2007)

Hereditary fibrinogen amyloidosis is characterized by deposition of amyloid fibrils in renal glomeruli. The subunit protein of the amyloid fibrils is a proteolytic fragment of the fibrinogen Aalpha-chain. To investigate the structure of fibrinogen amyloid, fibrils were extracted from the tissues of a patient and studied by X-ray fiber diffraction and electron microscopy. We have carried out a full structural characterization of amyloid fibrils taken from disease tissue. These studies revealed that ex vivo fibrinogen amyloid fibrils have a cross-beta structure similar to other chemical types of amyloid fibrils.
Cytochrome bc1 complexes of microorganisms (1990)

The cytochrome bc1 complex is the most widely occurring electron transfer complex capable of energy transduction. Cytochrome bc1 complexes are found in the plasma membranes of phylogenetically diverse photosynthetic and respiring bacteria, and in the inner mitochondrial membrane of all eucaryotic cells. In all of these species the bc1 complex transfers electrons from a low-potential quinol to a higher-potential c-type cytochrome and links this electron transfer to proton translocation. Most bacteria also possess alternative pathways of quinol oxidation capable of circumventing the bc1 complex, but these pathways generally lack the energy-transducing, protontranslocating activity of the bc1 complex. All cytochrome bc1 complexes contain three electron transfer proteins which contain four redox prosthetic groups. These are cytochrome b, which contains two b heme groups that differ in their optical and thermodynamic properties; cytochrome c1, which contains a covalently bound c-type heme; and a 2Fe-2S iron-sulfur protein. The mechanism which links proton translocation to electron transfer through these proteins is the proton motive Q cycle, and this mechanism appears to be universal to all bc1 complexes. Experimentation is currently focused on understanding selected structure-function relationships prerequisite for these redox proteins to participate in the Q-cycle mechanism. The cytochrome bc1 complexes of mitochondria differ from those of bacteria, in that the former contain six to eight supernumerary polypeptides, in addition to the three redox proteins common to bacteria and mitochondria. These extra polypeptides are encoded in the nucleus and do not contain redox prosthetic groups. The functions of the supernumerary polypeptides of the mitochondrial bc1 complexes are generally not known and are being actively explored by genetically manipulating these proteins in Saccharomyces cerevisiae.
Generation of horizontally polarized shear waves in ferromagnetic materials using magnetostrictively coupled meander-coil electromagnetic transducers (1979)

A new electromagnetic transducer configuration is described for generating horizontally polarized shear (SH) waves in ferromagnetic materials. The transducer consists of a meander coil and static bias magnetic field parallel to the coil elements. This configuration generates no ultrasonic waves in a nonmagnetic metal since the induced eddy currents are parallel to the bias field and the driving Lorentz forces vanish. However, the configuration provides coupling to SH waves in ferromagnetic materials through magnetostrictive effects. Experimental measurements of the variation of transduction efficiency with bias field in nickel and 4130 steel plate are presented and compared to the efficiency obtained with the same meander coils when the bias is rotated 90° in the plane of the plate so that antisymmetric Lamb waves are generated. Peak efficiencies occur at considerably different bias fields for the two configurations. This result, as well as other features in the data, are interpreted in terms of a simple model.