gebhart/patrepeval huggingface dataset:
A possible model for the stereospecificity in the syndiospecific polymerization of propene with group 4a metallocenes (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA possible model for the stereospecificity in the syndiospecific polymerization of propene with group 4a metallocenesLuigi Cavallo, Gaetano Guerra, Michele Vacatello, and Paolo CorradiniCite this: Macromolecules 1991, 24, 8, 1784–1790Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April 1991https://pubs.acs.org/doi/10.1021/ma00008a015https://doi.org/10.1021/ma00008a015research-articleACS PublicationsRequest reuse permissionsArticle Views269Altmetric-Citations150LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Bringing tabletop technologies to kindergarten children (2009)

Taking computer technology away from the desktop and into a more physical, manipulative space, is known that provide many benefits and is generally considered to result in a system that is easier to learn and more natural to use. This paper describes a design solution that allows kindergarten children to take the benefits of the new pedagogical possibilities that tangible interaction and tabletop technologies offer for manipulative learning. After analysis of children's cognitive and psychomotor skills, we have designed and tuned a prototype game that is suitable for children aged 3 to 4 years old. Our prototype uniquely combines low cost tangible interaction and tabletop technology with tutored learning. The design has been based on the observation of children using the technology, letting them freely play with the application during three play sessions. These observational sessions informed the design decisions for the game whilst also confirming the children's enjoyment of the prototype.
AN EFFICIENT METHOD FOR THE PREPARATION OF <i>THREO</i> CROSS-ALDOLS FROM SILYL ENOL ETHERS AND ALDEHYDES USING TRITYL PERCHLORATE AS A CATALYST (1985)

Abstract Threo cross-aldol products are predominantly formed in good yields by treating tert-butyldimethylsilyl enol ethers with aldehydes in the presence of a catalytic amount of trityl perchlorate.
[Hereditary breast cancer]. (2005)

Norwegian health care for women at risk of inherited breast cancer conforms with the European consensus guidelines published in 1999 and the Norwegian legislation regulating the use of predictive genetic testing. This paper represents a consensus between all medical genetic institutions in Norway handling inherited breast cancer through the Norwegian Group on Inherited Cancer. It is an update based on new knowledge, the structure of our health service and locally available technology and health care resources. The indications for referring patients to genetic testing are maintained. The demonstration of local founder BRCA1 mutations has been used to develop a high capacity for testing for these mutations. Mutation carriers should be offered annual MRI of the breasts for early diagnosis. Oophorectomy at end of childbearing ages is advocated in BRCA mutation carriers and breast-ovarian kindreds. The clinical geneticists have the role of coordinating health service to those in need, and are required to collaborate to present the empirical results of the effects of the interventions.
Antiplatelet Effect of Aspirin in Patients With Cerebrovascular Disease (2003)

A significant proportion of patients taking low-dose aspirin or enteric-coated aspirin have normal platelet function as measured by the PFA-100 test. If these results correlate with clinical events, they have broad implications in determining how aspirin is used and monitored.
Selective Photodynamic Therapy by Targeted Verteporfin Delivery toExperimental Choroidal Neovascularization Mediated by a Homing Peptide toVascular Endothelial Growth Factor Receptor-2 (2004)

Targeted PDT for CNV is feasible and may offer a qualitative improvement in current treatments for patients with age-related macular degeneration. This study provides the basis for further preclinical studies of targeted PDT strategies and subsequent clinical trials.
Query Transformations for Result Merging (2014)

Abstract : This paper describes Carnegie Mellon University's entry at the TREC 2014 Federated Web Search track (FedWeb14). Federated search pipelines typically have two components: (i) resource-selection, and (ii) result-merging. This work documents experiments to modify queries to merge results in the federated-search pipeline. Approaches from previous attempts at solving this problem involved custom query- document similarity scores or rank-combination methods. In this document, we explore how term-dependence models and query expansion strategies influence result-merging.
Testing of chemically treated adsorbent air purifiers (1993)

New highly sensitive continuous monitors permit testing of air filters at parts-per-billion contaminant concentrations. This article describes testing of air purification filters intended for use in the National Archives 2 building in College Park, Maryland, using a test procedure that simulates the actual conditions of use. This test demonstrates both the effectiveness of the adsorbers at low contaminant levels, and the capability of existing instruments for conducting such tests. ASHRAE TC 2.3 (Gaseous Air Contaminants and Gas Contaminant Removal Equipment) is currently sponsoring research projects (follow-on studies to ASHRAE Project RP-674) aimed at developing a standard that will test and rate the performance of different types of gas phase air purification equipment at low concentrations. The work detailed in this article represents a first of this type of testing and a technical benchmark that may aid in the further development of ASHRAE gas phase performance standards.
Oleophilic Ion-Exchange Polymers. I (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOleophilic Ion-Exchange Polymers. IHarry P. Gregor, Guenther K. Hoeschele, J. Potenza, A. G. Tsuk, R. Feinland, M. Shida, and Ph. TeyssiéCite this: J. Am. Chem. Soc. 1965, 87, 24, 5525–5534Publication Date (Print):December 1, 1965Publication History Published online1 May 2002Published inissue 1 December 1965https://pubs.acs.org/doi/10.1021/ja00952a001https://doi.org/10.1021/ja00952a001research-articleACS PublicationsRequest reuse permissionsArticle Views196Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Adsorption of divalent cations to bilayer membranes containing phosphatidylserine. (1981)

The Stern equation, a combination of the Langmuir adsorption isotherm, the Boltzmann relation, and the Grahame equation from the theory of the diffuse double layer, provides a simple theoretical framework for describing the adsorption of charged molecules to surfaces. The ability of this equation to describe the adsorption of divalent cations to membranes containing brain phosphatidylserine (PS) was tested in the following manner. Charge reversal measurements were first made to determine the intrinsic 1:1 association constants of the divalent cations with the anionic PS molecules: when the net charge of a PS vesicle is zero one-half of the available sites are occupied by divalent cations. The intrinsic association constant, therefore, is equal to the reciprocal of the divalent cation concentration at which the mobility of a PS vesicle reverses sign. The Stern equation with this association constant is capable of accurately describing both the zeta potential data obtained with PS vesicles at other concentrations of the divalent cations and the data obtained with with vesicles formed from mixtures of PS and zwitterionic phospholipids. Independent measurements of the number of ions adsorbed to sonicated PS vesicles were made with a calcium-sensitive electrode. The results agreed with the zeta potential results obtained with multilamellar vesicles. When membranes are formed at 20 degrees C in 0.1 M NaCl, the intrinsic 1:1 association constants of Ni, Co, Mn, Ba, Sr, Ca, and Mg with PS are 40, 28, 25, 20, 14, 12, and 8 M-1, respectively.
Vibrotactile feedback in steering wheel reduces navigation errors during GPS-guided car driving (2011)

We show that vibrotactile feedback displayed through the steering wheel of a car can reduce the perceptual and cognitive load of the driver, leading to less distraction and fewer navigation errors. To demonstrate the concept, two vibration motors are mounted onto the steering wheel of a driving simulator and driving experiments are performed in virtual environments under two different sensory conditions (auditory alone and auditory and vibrotactile feedback together). The results of our experiments with 12 subjects show that, if passenger auditory noise and distraction exist in the environment, the navigation errors (making a wrong turn or taking a wrong exit) are reduced when vibrotactile feedback is displayed to the users in tandem with the GPS-based voice commands.
HOMOGENEOUS REACTOR TEST. SUMMARY REPORT FOR THE ADVISORY COMMITTEE ON REACTOR SAFEGUARDS (1955)

The Homogeneous Reactor Test (HRT) is the experimental reactor facility (Frontispiece) being designed and constructed at ORNL as the next step in homogeneous reactor development between the 1-Mv HRE and a "full-scale" power station. The HRT will provide an integrated test at 5 to 10 Mv for the flowsheet and equipment designs on which the full-scale effort will be based. Furthermore, its design is such that several homogeneous systems which require essentially the same operating equipment may be tested with comparatively minor modifications of the original reactor installation. The reactor will be assembled in the building which housed the HRE, located in the experimental reactor exclusion area approximately one mile south of the oak ridge laboratory. (See figure 1) / It is the purpose of this report to provide information with which the hazardous aspects of this reactor may be evaluated. Briefly, it will be shown after a statement of purpose and a general description of the reactor that: 1. The design characteristics and equipment requirements are such that escape of highly reactive material from the reactor piping is unlikely. 2. Should the entire core and blanket contents suddenly escape from the reactor system, a seal-welded steel tank surrounding the system will prevent the leakage of a significant quantity of activity into the building. The biological hazards resulting from the destruction of the reactor and shield by bombing or other remote causes are presented in detail.
Tomosynthesis Reconstruction from Multi-Beam X-Ray Sources (2006)

We investigate methods for reconstructing tomosynthesis data using arrays of microfabricated X-ray sources and area CCD detectors. Tomosynthesis is a 3D imaging technique for limited-angle tomography that uses multiple radiographic images taken from an X-ray source placed at several positions to estimate a 3D distribution of X-ray attenuation. In our implementation, the moving X-ray source is replaced with multiple carbon nanotube field-emission X-ray sources fabricated on a single wafer. The sources are individually addressable, so the motion of the single X-ray source in traditional tomosynthesis is replaced by sequential sampling of the individual sources. Reconstruction is performed using the ordered-subsets convex (OSC) algorithm with pre-computed geometry factors and an image shearing technique for efficiency. Because of the limited resolution of tomosynthesis along the primary direction of projection, reconstructions are computed on non-cubic voxels for relatively thick slabs. We demonstrate the capabilities of the reconstruction technique on simulated data and breast phantom data from a prototype device. Reconstructions for an 11-beam system with 1000times1000 pixels per projection onto a 800times800times20 grid require 55 minutes ( 10 iterations) on a 3.2 GHz workstation with 2 GB memory. We conclude that this implementation of the OSC algorithm is effective for reconstructing tomosynthesis datasets
Impact of adjuvants on CD4+ T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial (2016)

Immunogenicity and safety of different adjuvants combined with a model antigen (HBsAg) were compared. Healthy HBV-naïve adults were randomized to receive HBs adjuvanted with alum or Adjuvant Systems AS01B, AS01E, AS03A or AS04 at Days 0 and 30. Different frequencies of HBs-specific CD4+ T cells 14days post dose 2 but similar polyfunctionality profiles were induced by the different adjuvants with frequencies significantly higher in the AS01B and AS01E groups than in the other groups. Antibody concentrations 30days post-dose 2 were significantly higher in AS01B, AS01E and AS03A than in other groups. Limited correlations were observed between HBs-specific CD4+ T cell and antibody responses. Injection site pain was the most common solicited local symptom and was more frequent in AS groups than in alum group. Different adjuvants formulated with the same antigen induced different adaptive immune responses and reactogenicity patterns in healthy naïve adults. The results summary for this study (GSK study number 112115 - NCT# NCT00805389) is available on the GSK Clinical Study Register and can be accessed at www.gsk-clinicalstudyregister.com.
A Prospective Study of High-Grade Cervical Neoplasia Risk Among Human Papillomavirus-Infected Women (2002)

Smoking is associated with an increased risk of invasive cervical cancer in women who are infected with oncogenic HPV. Subsequent studies should examine the role of smoking in the multistage pathogenesis of cervical cancer.
Ectopic endometrium in human foetuses is a common event and sustains the theory of müllerianosis in the pathogenesis of endometriosis, a disease that predisposes to cancer (2009)

We propose that a cause of endometriosis is the dislocation of primitive endometrial tissue outside the uterine cavity during organogenesis.
Models and algorithms for duplicate document detection (1999)

This paper introduces a framework for clarifying and formalizing the duplicate document detection problem. Four distinct models are presented, each with a corresponding algorithm for its solution derived from the realm of approximate string matching. The robustness of these techniques is demonstrated through a set of experiments using data reflecting real-world degradation effects.
Future of Pharmacogenetics-Based Therapy for Tuberculosis (2014)

Personalized medicine uses technology to enable a level of personalization not previously practical. Currently, tuberculosis (TB) therapy is not personalized. Previous reports have shown that a genetic polymorphism of NAT2 is associated with large interindividual and inter-racial differences in the toxicity and efficacy of isoniazid. Herein, we show the safety and efficacy of a pharmacogenetics-based standard TB therapy and also provide a schematic presentation that proposed therapeutic approaches for latent TB infection (LTBI) using NAT2 genotyping. Our data show that the pharmacogenetics-based TB therapy is safer and more efficacious than the standard therapy. Therefore, the therapy using NAT2 genotyping proposed for LTBI herein will be safer and more efficacious than the standard LTBI therapy. Introduction of this therapy with NAT2 genotyping will be one of the cornerstones of personalized medicine.
Solid-Supported Cross Metathesis and the Role of the Homodimerization of the Non-immobilized Olefin (2008)

We have prepared immobilized olefins as models for the cross metathesis using different olefin partners in the presence of second generation Grubbs and Hoveyda-Grubbs precatalysts. We have demonstrated that solid-phase cross metathesis is strongly dependent on the degree of homodimerization of the non-immobilized olefin and the reactivity of such a homodimer. As in the homogeneous phase, the Hoveyda-Grubbs precatalyst was better for immobilized alpha,beta-unsaturated carbonyl compounds.
Targeting Thioredoxin Reductase: Anticancer Agents and Chemopreventive Compounds (2010)

Thioredoxin reductase plays a critical role in the regulation of cancer cell apoptosis, making it an attractive target for the design of new anticancer drugs. Several classes of compounds have been considered as potential antitumor or chemopreventive agents; most of them apparently interact with thioredoxin reductase's C-terminal redox center.
Lean stability augmentation for premixing, prevaporizing combustors (1979)

An experimental program was conducted to investigate techniques for improving the lean combustion limits of premixing, prevaporizing combustors applicable to gas turbine engine main burners. Augmented flameholders employing recessed perforated plates, catalyzed tube bundles, and configurations in which pilot fuel was injected into the wakes of V-gutters or perforated plates were designed and tested. Stable operation of the piloted designs was achieved at equivalence ratios as low as 0.25; NOx emissions of less than 1.0 g/kg at simulated turbine engine cruise conditions were obtained. A piloted perforated plate employing four percent pilot fuel flow produced the best performance while meeting severe NOx constraints.
An Integrated EMI Choke for Differential-Mode and Common-Mode Noise Suppression (2009)

This letter presents a novel integration approach for the electromagnetic interference choke. A low-permeability differential-mode (DM) choke is placed within the open window of the common-mode (CM) choke. Both chokes share the same winding structure. With the proposed approach, the footprint of inductors is greatly reduced, and high-DM inductance can be achieved. First, small-signal measurement is carried out to demonstrate the design concept and the symmetry of the proposed structure. Then large-signal experimental results verify the attenuation characteristics, as well as the thermal performance.
A Data Model to Support End User Software Engineering (2007)

Many end user programming tools such as spreadsheets and databases offer poor support for representing data at a level of abstraction that is intuitive to users. For example, users must work with "strings" rather than person names, phone numbers, or street addresses. As a result, validating and manipulating data is difficult. This thesis develops a new user-extensible model for semi-structured data items. Each "tope" within this model defines how to recognize a kind of data item based on format and context, and how to transform that kind of item among valid formats. To show the usefulness of this model, we provide an environment to help end-user programmers to create, share, and apply topes, enabling these users to quickly implement data validation and reformatting functionality.
Real-Time Dense and Accurate Parallel Optical Flow using CUDA (2009)

A large number of processes in computer vision are based on the image motion measurement, which is the projection of the\nreal displacement on the focal plane. Such a motion is currently approximated by the visual displacement field, called optical\nflow. Nowadays, a lot of different methods are commonly used to estimate it, but a good trade-off between execution time and\naccuracy is hard to achieve with standard integrations. This paper tackles the problem by proposing a parallel implementation\nof the well-known pyramidal algorithm of Lucas & Kanade, in a Graphics Processing Unit (GPU). It is programmed using the\nCompute Unified Device Architecture from NVIDIA corporation, to compute a dense and accurate velocity field at about 15 Hz\nwith a 640 480 image definition.
Streamware (2008)

Recently, the number of cores on general-purpose processors has been increasing rapidly. Using conventional programming models, it is challenging to effectively exploit these cores for maximal performance. An interesting alternative candidate for programming multiple cores is the stream programming model, which provides a framework for writing programs in a sequential-style while greatly simplifying the task of automatic parallelization. It has been shown that not only traditional media/image applications but also more general-purpose data-intensive applications can be expressed in the stream programming style. In this paper, we investigate the potential to use the stream programming model to efficiently utilize commodity multicore general-purpose processors (e.g., Intel/AMD). Although several stream languages and stream compilers have recently been developed, they typically target special-purpose stream processors. In contrast, we propose a flexible software system, Streamware, which automatically maps stream programs onto a wide variety of general-purpose multicore processor configurations. We leverage existing compilation framework for stream processors and design a runtime environment which takes as input the output of these stream compilers in the form of machine-independent stream virtual machine code. The runtime environment assigns work to processor cores considering processor/cache configurations and adapts to workload variations. We evaluate this approach for a few general-purpose scientific applications on real hardware and a cycle-level simulator set-up to showcase scaling and contention issues. The results show that the stream programming model is a good choice for efficiently exploiting modern and future multicore CPUs for an important class of applications.