gebhart/patrepeval huggingface dataset:
Human T cell leukemia virus type I prevents cell surface expression of the T cell receptor through down-regulation of the CD3- <i>gamma</i> , - <i>delta</i> , - <i>epsilon</i> , and - <i>zeta</i> genes. (1990)

Infection and transformation by human T cell leukemia virus type I (HTLV-I) up-regulates expression of several inducible genes including those coding for cytokines involved in the proliferation of normal and leukemic T cells. We demonstrate that HTLV-I can also shut off expression of the CD3-gamma, delta, epsilon, and zeta genes that code for the constant elements of the TCR for Ag. In addition, the T cell-specific CD3-epsilon enhancer was found to be inactive in a HTLV-I-infected T cell clone. This HTLV-I-infected T cell clone (827-p19-II) that could be cultured in the absence of IL-2 lacked the CD3 proteins but did express the TCR-alpha and -beta proteins intracellularly. In the absence of the CD3-gamma, delta, epsilon, and zeta polypeptide chains the disulfide bridged TCR-alpha/beta heterodimer was not formed and the Ag receptor did not appear at the cell surface. These results allowed two major conclusions: first, HTLV-I infection has an effect on the T cell specific regulatory elements that coordinately regulate CD3-gamma, delta, epsilon, and zeta expression and second, the CD3-gamma, delta, epsilon, and zeta proteins are necessary for formation and routing the variable TCR-alpha/beta (or -gamma/delta) heterodimer to the human T cell surface.
SMS Text Compression through IDBE (Intelligent Dictionary based Encoding) for Effective Mobile Storage Utilization (2014)

Effective storage utilization is the key concept for better working of any operating system. Even operating systems used for mobile phones are not an exception for this fact. This paper proposes a technique for maximizing the utilization of the storage space present in mobile phones. Thus it is important to utilize the space occupied by SMS files in phone’s memory, which take maximum space. The objective involved is designing a semantic dictionary based on Intelligent Dictionary Based Encoding (IDBE) which provides a high text compression ratio to utilize the space in phone’s memory. When SMS file will be received, English words present in the text will be replaced by the respective short words in the designed semantic dictionary. Thus replacing English words by the respective short forms reduces the space occupied by the SMS file. The paper describes the IDBE Compression Techniques for SMS Text Compression.
Synthetic aperture radar with a non-uniform pulse repetition interval (2002)

Based on recent developments it has become feasible to combine the multiple pulse integration of synthetic aperture radar (SAR) with the temporal agility of nonuniform pulse repetition intervals (PRI). This combination can bring to the traditional SAR system both strong resistance to countermeasures and interception, and high sensitivity. A significant problem which must be addressed in SAR systems is the possible smearing of the azimuth dimension of the image due to Doppler sidelobes which are too high. This issue is even more serious with a non-uniform PRI waveform. Traditionally sidelobes are controlled with techniques such as amplitude weighting. However, these simpler techniques are not adequate for non-uniform PRI waveforms. One method for increasing the sidelobe rejection capability of these waveforms is through the use of interpolation based techniques.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Synthesis of Aqueous Polyethylene Dispersions with Electron-Deficient Neutral Nickel(II) Catalysts with Enolatoimine Ligands (2007)

A series of new, electron-poor neutral κ2-N,O chelated Ni(II) complexes were studied for ethylene polymerization in aqueous emulsion. Complexes based on enolatoimine ligands bearing electron-withdrawing trifluoromethyl and trifluoroacetyl groups [κ2-N,O-{2,6-R2C6H3NC(H)C(COCF3)C(O)CF3}]Ni(L)Me (4a, R = iPr, L = pyridine; 4b, R = 3,5-(CF3)2C6H3, L = pyridine; 5b, R = 3,5-(CF3)2C6H3, L = PPh3) were prepared. The complexes are very active in aqueous emulsions, with 1.4 × 104 TO h-1 for 4a (50 °C) and 1.9 × 104 TO h-1 for 4b (70 °C), affording stable polyethylene dispersions. The phosphine complex 5b is active in the absence of a phosphine scavenger, with similar activities as 4b. Polyethylenes of typically Mw 3 × 104 g mol-1 (Mw/Mn 2.0−2.5) with 25−50 branches per 1000 carbon atoms and Tm 94−112 °C are obtained.
A supervised ANN method for memory failure signature classification (2012)

Failure bitmaps of manufactured memory arrays may contain the information associated to some systematic defects and have hence been used to monitor the process and improve the memory yield. It is very important to develop a method to extract and classify the fault signatures in the failure bitmaps. The fault signatures can be classified into two categories: local fault signatures and global fault signatures. Focusing on the local fault signatures, this paper introduces a supervised one-layer ANN method to solve the signature classification problem. The method is efficient for recognizing the local fault signatures in the failure bitmaps, and more importantly, it has the ability to find new signatures unseen before.
Detection of Hepatitis C Virus RNA in Normal Cervical Smears (2003)

Detection of Hepatitis C Virus RNA in Normal Cervical SmearsSir-Manavi et al. [1] recently reported results of a study that used RT-PCR and fluorescence in situ hybridization to detect hepatitis C virus (HCV) RNA.The authors reported that 36.4% of cervical smears samples obtained from 22 study subjects were positive for HCV RNA and that HCV genomic RNA was detected in cervical lymphocytes, but not in cervical granulocytes or epithelial cells.We have several questions about the experiments and results.In the article by Manavi et al. [1], figure 3 indicates that 50% of cervical cells were positive for HCV RNA, an unusually high proportion.A growing body of literature supports the understanding that HCV, like other flaviviruses, replicates in the cell cytoplasm [2][3][4].Moreover, fractionation experiments and immunomicroscopy of recent HCV replicons have localized HCV nonstructural proteins to endoplasmic reticulum membranes in cell cytoplasm [5].Hence, the demonstration of nuclear localization of HCV replication complexes raises questions about the specificity of the procedure used by Manavi et al. [1].What region of the genome did the probe hybridize to?Is the signal due to RNA or DNA?Finally, what is the rationale for the statement in the figure legend that "HCV RNA was expressed and detectable in the nuclei of cervical smear lymphocytes?"In table 2 of their article [1], the authors report that specimens contained 0%-20% hemoglobin.Were the cervical specimens washed before RT-PCR was performed?Was the last wash sample PCR negative for HCV?These data are needed to interpret the authors' conclusions that 50% of cervical epithelial cells contained HCV.
Effect of Benzo-Annelation on Local Aromaticity in Heterocyclic Conjugated Compounds (2014)

The effect of benzo-annelation on the local aromaticity of the central ring of acridine (1), 9H-carbazole (2), dibenzofuran (3), and dibenzothiophene (4) was analyzed by means of the energy effects (ef), pairwise energy effects (pef), multicenter delocalization index (MCI), electron density at ring critical points (ρ(r(C))), harmonic oscillator model of aromaticity (HOMA), and nucleus independent chemical shifts (NICS). According to energetic, electron delocalization, and geometrical indices, angular benzo-annelation increases, whereas linear benzo-annelation decreases, the extent of the local aromaticity of the central ring containing heteroatoms. The local aromaticity of the central heterocyclic ring in the examined molecules can significantly vary by applying different modes of benzo-annelation. The NICS values do not always support the results obtained by the other aromaticity indices and, in some cases, lead to completely opposite conclusions.
The functioning of religions from a modern psychoanalytic perspective (2000)

This paper considers the personal psychological development which can take place in the adherents of certain religions, and compares it with the personal development which can take place in a psychoanalysis. The author argues that the preoccupations of different religions are very various, and to understand their functioning it is important to recognise the variety of their goals. Using the Kleinian notion of psychic ‘positions', and with the help of a neuro-scientific model, it becomes possible to conceptualise the psychological effectiveness of both psychoanalysis and the religions, and to relate them intelligibly. There continues, however, to be a radical difference between the ways in which psychoanalysis and the religions cause their psychological effects, which is best seen by considering the nature of their objects.
Who would want to be a nurse? Violence in the workplace - a factor in recruitment and retention (2002)

In a climate of a declining nursing workforce where violence and hostility is a part of the day-to-day lives of most nurses, it is timely to name violence as a major factor in the recruitment and retention of registered nurses in the health system. Workplace violence takes many forms such as aggression, harassment, bullying, intimidation and assault. Violent acts are perpetrated against nurses from various quarters including patients, relatives, other nurses and other professional groups. Research suggests that nurse managers are implicated in workplace violence and bullying. Furthermore, there may be a direct link between episodes of violence and aggression towards nurses and sick leave, burnout and poor recruitment and retention rates. This paper explores what is known about workplace violence as it affects nurses, and calls for managerial support and policy to act to improve work environments for all nurses.
Exposure to Lead and Specific Attentional Problems in Schoolchildren (1994)

A pilot study was carried out to investigate the relationship between exposure to lead and attention in children. The participants were 43 boys, 8 to 12 years of age, attending special schools for children with educational and/or learning problems (so called LOM schools). Children with probable causes of attentional or memory problems other than lead contamination were excluded from the study. Various aspects of attention were measured using neuropsychological tests. As an assessment of body lead burden, lead concentration in the boys' hair was measured by means of the Synchrotron Radiation-Induced X-ray Fluorescence technique (SXRF). Information was collected about variables that possibly could influence attention and/or body lead burden (confounding factors). A multiple regression analysis was used to determine the contribution of lead to variance in performance, after correction for confounding factors. The results showed that children with relatively high concentrations of lead in their hair reacted significantly slower in a simple reaction-time task than did children with relatively low concentrations of lead in their hair. In addition, the former were significantly less flexible in changing their focus of attention, even after correction for the influence of their delayed reaction time.
A preliminary study on the highway piezoelectric power supply system (2017)

Pavement piezoelectric energy harvesting technique is to use a Piezoelectric Energy Harvester (PEH) to convert the mechanical energy of vehicles into electrical energy. A lot of research has been done on the technology of piezoelectric energy collection, but it is mainly focused on the theoretical model and the laboratory tests and lacks the on-site performance evaluation. In this paper, a stacked array type PEH is designed with protection package, which can improve the performance and the service life of the PEH. The demonstration project is also carried out to test the field performance. It is found that under the actual vehicle loading, the obtained piezoelectric energy can successfully light LED signs.
Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in china (2011)

In China, narcolepsy onset is highly correlated with seasonal and annual patterns of upper airway infections, including H1N1 influenza. In 2010, the peak seasonal onset of narcolepsy was phase delayed by 6 months relative to winter H1N1 infections, and the correlation was independent of H1N1 vaccination in the majority of the sample.
A DNA repair gene required for the incision of damaged DNA is essential for viability in Saccharomyces cerevisiae. (1983)

A diploid strain (RAD3/RAD3) of Saccharomyces cerevisiae was transformed with an integration plasmid containing an internal fragment of the cloned yeast RAD3 gene. Integration by homologous recombination inactivated one of the diploid RAD3 genes, creating a recessive mutation. This mutation is inferred to be lethal in haploid cells since sporulation of diploid transformants segregated two viable and two inviable spores per tetrad, while integration of plasmids containing one or the other end of the RAD3 gene resulted in diploid transformants that segregated normally--i.e., four viable spores in each tetrad. Evidence that integration of the internal fragment occurred specifically at one of the RAD3 genes in the diploid is provided by DNA . DNA hybridizations. In addition, transformation of a diploid strain heterozygous for the RAD3 gene (RAD3/rad3-2) (carrying a rad3 mutation that does not affect the viability of haploid cells) results in the rad- phenotype in half of the transformants, indicating that the RAD3 gene was inactivated in these cells.
Uprating Transmission Lines through the use of an innovative real-time monitoring system (2011)

This paper describes a brand new method of real-time monitoring of overhead transmission lines. The method makes use of what is called the “Ampacimon” system. The system uses an Ampacimon module, which is a real time monitoring device that deduces the sag by vibration analysis without the need for any line data or environmental data. The Ampacimon system has been proven to be accurate within a sag error margin of ±2%.
<i>CYP2C19</i> Polymorphism and Proton Pump Inhibitors (2004)

Proton pump inhibitors such as omeprazole (esomeprazole), lansoprazole, pantoprazole and rabeprazole are eliminated by the hepatic route and the polymorphic CYP2C19 is mainly involved in their metabolism. In different populations three phenotypes have been identified: extensive metabolizers, poor metabolizers and individuals carrying one wild type and one mutant allele (het extensive metabolizers). Systemic exposure to the proton pump inhibitors as expressed by the AUC (area under the plasma level time profiles) is 5-12-times higher in poor metabolizers than in extensive metabolizers. As the pharmacodynamic response (elevation of intragastric pH) to the proton pump inhibitors is related directly to their AUC, a much higher pH can be monitored over 24 hr in poor metabolizers than in extensive metabolizers. Furthermore, clinical efficacy of all proton pump inhibitors depend on maintaining intragastric pH above certain threshold levels and significantly higher eradication rates of Helicobacter pylori have been observed in patients of the poor metabolizers and het extensive metabolizers phenotype if compared to extensive metabolizers. Likewise, limited data suggest that proton pump inhibitors-induced healing rates in gastro-oesophageal reflux disease are apparently higher in poor metabolizers/het extensive metabolizers than in extensive metabolizers of CYP2C19. Therefore initial genotyping for this enzyme and higher dosage in extensive metabolizers is likely to improve the clinical efficacy of proton pump inhibitors.
Recording and Analysis of AC Impedance Data for Corrosion Studies (1981)

A brief review is given of the application of AC impedance measurements to electrochemical processes. Only very few applications for corrosion processes have been reported. The background and various methods of analysis of AC impedance data are discussed. The parameters which characterize the corrosion behavior can be determined from plots of the frequency dependence of the impedance in the complex plane which result in semicircles for very simple cases. These parameters can also be determined from straight line plots of the real part Z′ vs ωZ″ or Z″/ω, where Z″ is the imaginary part of the impedance and the frequency f is expressed as ω = 2πf. Additional methods of analysis include evaluation of the frequency dependence of the series resistance Rs and series capacitance Cs, the absolute value of the impedance |Z| and the phase angle δ. Experimental results obtained with a system for automatic recording and analysis of impedance data are given for a dummy cell which represents a corroding electrode.
An X-band 50% bandwidth high-power GaN HEMT T/R switch (2010)

An X-band high-power T/R switch utilizing GaN HEMT has been developed. The switching circuit employed an asymmetric series-shunt/shunt configuration with bandwidth extension circuits. By using the circuit topology, the switch circuit can achieve high-power and low-loss performance at Tx-mode and low insertion loss at Rx-mode in broad bandwidth. To verify this methodology, we have fabricated a GaN HEMT switch, and the circuit has achieved the power handling capability of 20W and the insertion loss of 1.2dB at Tx-mode, 1.8dB at Rx-mode in 7–12GHz range.
Temperature monitoring of focused ultrasound therapy by MRI (1994)

The aim of the present study was to assess the feasibility of MRI monitoring the temperature distribution induced by focused ultrasound therapy of malignant tissue in vivo. Male Copenhagen rats bearing R3327-AT1 Dunning prostate tumors were sonicated in vivo with a self-constructed CW-ultrasound source. The sonication was performed in a conventional 1.5 T whole-body MR scanner. For MRI a T1-weighted saturation recovery TurboFLASH (SRTF) sequence (TR=10.2 ms, TE=4 ms, TI=300 ms, α=12°) with an acquisition time of 1.3 s per image was used. After sonication hypo-intense regions inside the tumors were monitored expanding centripetally off the focus by time. Tumor growth delay and postmortem histology correlated with the temperature distributions calculated from the SRTF signals. This will temperature to be controlled interactively during US hyperthermia
[Interventional and surgical arrhythmology: state of the art, problems and prospects for development]. (2003)

The paper considers the state-of-the-art, problems, and prospects for development of interventional and surgical arrhythmology in Russia, which is a multidisciplinary specialty which integrates present-day achievements of medicine and new technologies in the diagnosis and treatment of cardiac arrhythmias.
A 75.1dB SNDR 840MS/s CT ΔΣ modulator with 30MHz bandwidth and 46.4fJ/conv FOM in 55nm CMOS (2013)

This paper presents a 30MHz bandwidth continuous-time (CT) ΔΣ modulator with direct resistor feed-forward and fast excess loop delay (ELD) compensation method to enhance the loop stability. Moreover, the proposed design incorporates analog DAC background calibration and offset calibration for fully dynamic latch comparator. The modulator achieves 77.1dB DR and 75.1dB SNDR in 30MHz bandwidth, while occupying 0.071mm2 in 55nm CMOS and achieving a FoM (Power/(2BW·2ENOB)) of 46.4fJ/conv.
Isolation and Characterization of Novel Murine Epiphysis Derived Mesenchymal Stem Cells (2012)

These results indicate that EMSCs, a new type of MSCs established by our simple isolation method, are a preferable alternative for mice MSCs due to their better growth and differentiation potentialities.
Ueber die Methylirung von Brenzkatechin (1925)

Bei der Methylirung von Brenzkatechin in 20% iger alkalischer Losung wurde die hochste Ausbeute (35.6% der Theorie) an Guajacol erzielt, wenn man 0.84 Mol Dimethylsulfat auf 1 Mol Brenzkatechin einwirken lasst. Als Nebenprodukt trat dabei 25.28% Veratrol auf und wurden 5.96% Brenzkatechin zuruckgewonnen. Beim Erhitzen von je 1 Mol Brenzkatechin und festem Kali mit verschiedener Menge methyl-schwefersauren Kalis in einem Autoklaven auf 160°, so wird die beste Ausbeute an Guajacol (14.9%) erzielt, wenn man 2.5 Mol des letzteren Mittels anwendet.
Design and Analysis of Deterministic Distributed Beamforming Algorithms in the Presence of Noise (2013)

This paper presents a new deterministic closed-loop phase-alignment algorithm based on quantized feedback from the receiver for distributed beamforming. In contrast with previously proposed methods, which entailed repeated transmissions from all the nodes in the network, this new algorithm requires each node to transmit only once during the synchronization cycle. This drastically reduces the amount of power consumed to achieve phase alignment, yet the new algorithm converges at least as fast as all other existing schemes. In contrast with previous analyses of distributed beamforming based on random phase updates, where noise had been disregarded, here it is explicitly included in the models and shown to have a considerable effect that cannot be ignored. With and without noise, analytical expressions that characterize the performance of the new algorithm are provided, with emphasis on various limiting regimes of interest.
Porous silica spheres as indoor air pollutant scavengers (2010)

Porous silica spheres were investigated for their effectiveness in removing typical indoor air pollutants, such as aromatic and carbonyl-containing volatile organic compounds (VOCs), and compared to the commercially available polymer styrene-divinylbenzene (XAD-4). The silica spheres and the XAD-4 resin were coated on denuder sampling devices and their adsorption efficiencies for VOCs evaluated using an indoor air simulation chamber. Real indoor sampling was also undertaken to evaluate the affinity of the silica adsorbents for a variety of indoor VOCs. The silica sphere adsorbents were found to have a high affinity for polar carbonyls and found to be more efficient than the XAD-4 resin at adsorbing carbonyls in an indoor environment.
HYPOTHALAMIC‐PITUITARY SARCOIDOSIS (1965)

SUMMARY Three cases of sarcoidosis involving the brain in the region of the hypothalamus are described. The lesions caused markedly different disturbances of hypothalamic‐pituitary function, ranging from anterior and posterior pituitary failure to a pure hypothalamic syndrome. Two patients had signs indicative of an intracranial space‐occupying lesion. Corticosteroid therapy was used in two cases, and produced remissions of diabetes insipidus which have lasted for six years.
Advanced scanning methods with tracking optical coherence tomography (2005)

An upgraded optical coherence tomography system with integrated retinal tracker (TOCT) was developed. The upgraded system uses improved components to extend the tracking bandwidth, fully integrates the tracking hardware into the optical head of the clinical OCT system, and operates from a single software platform. The system was able to achieve transverse scan registration with sub-pixel accuracy (~10 microm). We demonstrate several advanced scan sequences with the TOCT, including composite scans averaged (co-added) from multiple B-scans taken consecutively and several hours apart, en face images collected by summing the A-scans of circular, line, and raster scans, and three-dimensional (3D) retinal maps of the fovea and optic disc. The new system achieves highly accurate OCT scan registration yielding composite images with significantly improved spatial resolution, increased signal-to-noise ratio, and reduced speckle while maintaining well-defined boundaries and sharp fine structure compared to single scans. Precise re-registration of multiple scans over separate imaging sessions demonstrates TOCT utility for longitudinal studies. En face images and 3D data cubes generated from these data reveal high fidelity image registration with tracking, despite scan durations of more than one minute.