gebhart/patrepeval huggingface dataset:
A portable code generator for CRAY FORTRAN (1992)

One way to combine the powers of symbolic computing with numeric computing is to automaticaly derive and produce numeric code. This approach has important applications in science and engineering. Once the desired formulas and procedures are derived in a symbolic manipulation system, they can be translated into a target numeric language by a code generator . GENCRAY is a code generator written in the C language for portability. GENCRAY defines a LISP-style input language that is translated into either FORTRAN 77 or CRAY FORTRAN. By defining its own input syntax, GENCRAY becomes a free-standing code translator that can be made to work with any symbolic manipulation system. GENCRAY is portable to any computer system with a standard C compiler. Input to GENCRAY can come from a file or directly from a symbolic system through a pipe. On UNIX systems with Berkeley networking, GENCRAY also runs as a network server. The input syntax is customizable to allow both Common and Franz LISP input styles. In addition to generating easily vectorizable CRAY FORTRAN code, GENCRAY also provides high-level, easy-to-use parallel programming macros to produce parallel code for the multiprocessor CRAY systems. The features, applications, usage, and implementation of GENCRAY are described. Techniques for producing parallel codes are discussed and illustrated by a substantial example contained in the Appendix.
Genetic Engineering of Murine CD8+ and CD4+ T Cells for Preclinical Adoptive Immunotherapy Studies (2011)

T-cell receptor (TCR) gene therapy enables for the rapid creation of antigen-specific T cells from mice of any strain and represents a valuable tool for preclinical immunotherapy studies. Here, we describe the superiority of γ-retroviral vectors compared with lentiviral vectors for transduction of murine T cells and surprisingly illustrate robust gene-transfer into phenotypically naive/memory-stem cell like (TN/TSCM; CD62L(hi)/CD44(low)) and central memory (TCM; CD62L(hi)/CD44(hi)) CD8+ T cells using murine stem cell-based γ-retroviral vectors (MSGV1). We created MSGV1 vectors for a major histocompatibility complex-class I-restricted TCR specific for the melanocyte-differentiation antigen, glycoprotein 100 (MSGV1-pmel-1), and a major histocompatibility complex-class II-restricted TCR specific for tyrosinase-related protein-1 (MSGV1-TRP-1), and found that robust gene expression required codon optimization of TCR sequences for the pmel-1 TCR. To test for functionality, we adoptively transferred TCR-engineered T cells into mice bearing B16 melanomas and observed delayed growth of established tumors with pmel-1 TCR engineered CD8+ T cells and significant tumor regression with TRP-1 TCR transduced CD4 T cells. We simultaneously created lentiviral vectors encoding the pmel-1 TCR, but found that these vectors mediated low TCR expression in murine T cells, but robust gene expression in other murine and human cell lines. These results indicate that preclinical murine models of adoptive immunotherapies are more practical using γ-retroviral rather than lentiviral vectors.
The Formation of Boron‐Doped Polycrystalline Si with Extremely Low Resistivities at Low Temperatures (1994)

A process consisting of the deposition of amorphous silicon at low temperatures and subsequent annealing has been proposed for fabricating a boron‐doped polycrystalline silicon film with a low resistivity. This process realized large grain growth up to 3 to 5 μm, leading to a low resistivity of 1.4 mΩ · cm, which one‐half to about one‐third compared with that of direct deposited boron doped polysilicon. In addition to this, extremely low deposition temperature (∼350°C) using a mixture attained uniform boron concentration across the wafers.
Needle-based blocks for the 21st century ophthalmology (2010)

Aside from relative safety, modern needle blocks offer the advantage of lid akinesia without a need for a second injection for the seventh nerve that is often performed con-comitantly with retrobulbar block.
Functional and phenotypic upregulation of CD13/aminopeptidase-N on precursor-B acute lymphoblastic leukemia after in vitro stimulation. (1995)

Acute lymphoblastic leukemia (ALL) cells of precursor-B type were assessed for expression of the cell surface peptidase CD13 (aminopeptidase-N) after 72 hours' culture in 10% B cell growth factor (BCGF), TPA, or medium alone. CD13 was analyzed phenotypically using a specific monoclonal antibody (mAb) by flow cytometry, and also with a spectrophotometric enzyme assay to measure the cleavage of specific peptide substrates. CD13 antigen was induced in all 10 cases of precursor-B ALL after culture with BCGF, with weaker expression seen in cells incubated with TPA or in medium alone. Aminopeptidase-N-like enzymatic activity was also demonstrated in cultured cells, particularly after BCGF exposure. Using the mAb WM-15, which specifically inhibits aminopeptidase-N function, we demonstrated that induction of true aminopeptidase-N activity was largely restricted to BCGF-treated cells, in which approximately 20% of total aminopeptidase activity was due to aminopeptidase-N. Phenotypic expression of the peptidase CD10 (neutral endopeptidase) was not altered on cultured cells. These findings indicate that CD13 expression can be selectively upregulated on ALL cells in response to proliferative stimuli. This peptidase, in cooperation with CD10 and perhaps other surface enzymes, may act to regulate the concentration of molecules at the cell surface which influence the growth of precursor-B ALL cells.
Spinal Cord Ependymoma: Radical Surgical Resection and Outcome (2002)

We conclude that radical surgical resection of spinal cord ependymomas can be safely achieved in the majority of patients. A trend toward neurological improvement from a postoperative deficit can be expected between 1 and 3 months after surgery and continues up to 1 year. Postoperative dysesthesias begin to improve within 1 month of surgery and are significantly better by 1 year after surgery. The best predictor of outcome is the preoperative neurological status.
Increasing the Far-Ultraviolet Reflectance of Silicon-Oxide-Protected Aluminum Mirrors by Ultraviolet Irradiation* (1963)

The effect of ultraviolet irradiation on the visible and ultraviolet reflectance of silicon-oxide-protected aluminum mirrors was studied. The silicon oxide protective films were produced by evaporating silicon monoxide under various evaporation conditions. High deposition rates at low pressure result in films of true SiO which are absorbing in the ultraviolet and shorter wavelength region of the visible, and which are, therefore, unsuitable for protecting mirrors that are to be used in this spectral region. Films deposited at low rates and rather high pressures of oxygen (deposition rate <5 Å/sec at 8–10×10−5 Torr) consist predominantly of Si2O3, and exhibit strong absorptance only below λ=3000 Å. Their ultraviolet absorptance can be completely eliminated by ultraviolet irradiation from a quartz mercury burner. This makes it possible to produce well-protected aluminum mirrors with 92% reflectance down to λ=2200 Å. Infrared measurements have shown that the elimination of the ultraviolet absorptance of Si2O3 films by ultraviolet treatment is not caused by a conversion of Si2O3 into SiO2. The reflectance of aluminum coated with true SiO is not affected by ultraviolet irradiation. Data on the solar absorptance of silicon-oxide-protected aluminum mirrors are presented.
Evaluating Merging Strategies for Sampling-based Uncertainty Techniques in Object Detection (2019)

There has been a recent emergence of sampling-based techniques for estimating epistemic uncertainty in deep neural networks. While these methods can be applied to classification or semantic segmentation tasks by simply averaging samples, this is not the case for object detection, where detection sample bounding boxes must be accurately associated and merged. A weak merging strategy can significantly degrade the performance of the detector and yield an unreliable uncertainty measure. This paper provides the first in-depth investigation of the effect of different association and merging strategies. We compare different combinations of three spatial and two semantic affinity measures with four clustering methods for MC Dropout with a Single Shot Multi-Box Detector. Our results show that the correct choice of affinity-clustering combination can greatly improve the effectiveness of the classification and spatial uncertainty estimation and the resulting object detection performance. We base our evaluation on a new mix of datasets that emulate near open-set conditions (semantically similar unknown classes), distant open-set conditions (semantically dissimilar unknown classes) and the common closed-set conditions (only known classes).
Alterations of Extracellular Matrix Components and Proteinases in Human Corneal Buttons With INTACS for Post-Laser In Situ Keratomileusis Keratectasia and Keratoconus (2008)

Abnormal accumulation of fibrotic ECM components and proteinases near INTACS suggests ongoing lysis and remodeling of corneal stroma. Specific changes observed in each case may be related to underlying pathology.
Distributed self-diagnosis of VLSI mesh array processors (2002)

A distributed self-diagnosis algorithm for VLSI mesh arrays with small clusters of faults is presented. It allows only fault-free cells to make decisions and to propagate diagnosis results. Its time complexity is constant with respect to the number of processors. The diagnosability is proportional to the array size.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Criminal Prosecution of Insects (1937)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Single photons for quantum information systems Single photons for quantum information systems (2004)

gressed rapidly in recent years in the hope of addressing these needs. This field of research covers many topics, and is developing at an unprecedented scale with the involvement of researchers from many different leading-edge science and technology fields. Although it is very hard to predict how things will turn out in the future, it seems that as far as a hardware is concerned, important roles will be played by photonic qubits for quantum communication, nuclear spin qubits for quantum memory, and electron spin qubits for quantum information processing to connect them together. This paper introduces the latest research trends relating to the production of photonic qubits used for quantum communication and computation, with particular reference to the results obtained by the author’s group. In quantum cryptography, 1)
Risperidone, quetiapine, and olanzapine adjunctive treatments in major depression with psychotic features: a comparative study (2013)

Quetiapine, risperidone, and olanzapine, given as adjunctive treatment with SSRIS or SNRIs can significantly and equally improve depressive and psychotic symptoms, in the short-term treatment of major depression with psychotic features. The author recommends that large controlled trials be conducted to examine the differences in long-term efficacy and tolerance between the atypical antipsychotic agents, in the treatment of major depression with or without psychotic features.
The V-Groove Multijunction solar cell (1978)

A new type of silicon photovoltaic converter has been developed called the V-Groove Multijunction (VGMJ) solar cell. The VGMJ solar cell consists of an array of many individual diode elements connected in series to produce a high-voltage low-current output. All the elements of the cell are formed simultaneously from a single silicon wafer by V-groove etching. The results of detailed computer simulations predict a conversion efficiency in excess of 24 percent for this cell when it is operated in sunlight concentrated 100 or more times. The advantages of this cell over other silicon cells include the capability for greater than 20-percent conversion efficiency with only modest bulk carrier lifetimes, a higher open-circuit voltage, a very low series resistance, a simple one-mask fabrication procedure, and excellent environmental protection provided by a glass front surface.
The N-Terminal Region of IFITM3 Modulates Its Antiviral Activity by Regulating IFITM3 Cellular Localization (2012)

Interferon-inducible transmembrane (IFITM) protein family members IFITM1, -2, and -3 restrict the infection of multiple enveloped viruses. Significant enrichment of a minor IFITM3 allele was recently reported for patients who were hospitalized for seasonal and 2009 H1N1 pandemic flu. This IFITM3 allele lacks the region corresponding to the first amino-terminal 21 amino acids and is unable to inhibit influenza A virus. In this study, we found that deleting this 21-amino-acid region relocates IFITM3 from the endosomal compartments to the cell periphery. This finding likely underlies the lost inhibition of influenza A virus that completes its entry exclusively within endosomes at low pH. Yet, wild-type IFITM3 and the mutant with the 21-amino-acid deletion inhibit HIV-1 replication equally well. Given the pH-independent nature of HIV-1 entry, our results suggest that IFITM3 can inhibit viruses that enter cells via different routes and that its N-terminal region is specifically required for controlling pH-dependent viruses.
Cholinergic and GABAergic pathways in fly motion vision (2001)

The interaction of excitatory and inhibitory pathways is essential for the computation of visual motion responses and discussed in the context of the Reichardt model for motion detection.
A method for segmenting acoustic patterns, with applications to automatic speech recognition (1977)

Patterns derived by acoustic analysis of speech may be represented as a sequence of "segments", each described in terms such as length and mean spectrum. We present an automatic method of dividing the pattern from one utterance of a word into a sequence of segments. A "segment evaluation function" measures how well any given portion of the utterance can be represented as a single segment. The segmentation process itself simply finds the sequence of segments which best represents the whole pattern. Results are presented for several words and segment evaluation functions. Applications to automatic recognition of given words in connected speech are discussed.
A City-Wide Real-Time Traffic Management System: Enabling Crowdsensing in Social Internet of Vehicles (2018)

As an emerging platform based on ITS, SIoV is promising for applications of traffic management and road safety in smart cities. However, the endto- end delay is large in store-carry-and-forwardbased vehicular networks, which has become the main obstacle for the implementation of large-scale SIoV. With the extensive applications of mobile devices, crowdsensing is promising to enable realtime content dissemination in a city-wide traffic management system. This article first provides an overview of several promising research areas for traffic management in SIoV. Given the significance of traffic management in urban areas, we investigate a crowdsensing-based framework to provide timely response for traffic management in heterogeneous SIoV. The participant vehicles based on D2D communications integrate trajectory and topology information to dynamically regulate their social behaviors according to network conditions. A real-world taxi trajectory analysis-based performance evaluation is provided to demonstrate the effectiveness of the designed framework. Furthermore, we discuss several future.
QSAR Study of Angiotensin I-Converting Enzyme Inhibitory Peptides Based on Different Modeling Methods (2013)

A new ACE inhibitory peptides database was self-established.After the structures of peptide samples with different lengths were characterized using amino acid descriptors SVHEHS,the data obtained were treated for standardization by auto cross covariances(ACC).Then three modeling methods,namely multiple linear regression(MLR),partial least squares(PLS) and artificial neural network(ANN) were used to establish the models of the QSAR of ACE inhibitory peptides,respectively.The results showed that R2(correlation coefficient) of MLR,PLS and ANN models were 0.744,0.862 and 0.958,Q2LOO(leave-one-out cross-validated correlation coefficient) were 0.532,0.829 and 0.948,and Q2ext(external validated correlation coefficient) were 0.567,0.632 and 0.634,respectively.Hence,the combinations of SVHEHS and the above three modeling approaches were all useful for the QSAR of ACE inhibitory peptides,in which ANN modeling approach is the best.
Skeletal muscle proteasome can degrade proteins in an ATP-dependent process that does not require ubiquitin. (1989)

The proteasome (the multicatalytic endoproteinase complex) in mammalian tissues hydrolyzes proteins and several types of peptides. When this structure was isolated rapidly from rabbit skeletal muscle in the presence of glycerol, its various peptidase and protease activities showed a large reversible activation by physiological concentrations of ATP (Ka = 0.3-0.5 mM). Hydrolysis of succinyl-Leu-Leu-Val-Tyr-(4-methylcoumaryl-7-amide) was stimulated up to 12-fold by ATP, whereas degradation of casein and bovine serum albumin increased 4- to 7-fold. Neither ADP nor AMP had any effect. CTP, GTP, UTP, and the nonhydrolyzable analogs adenosine 5'-[beta,gamma-imino]triphosphate (AMPP[NH]P) and adenosine 5'-[alpha,beta-methylene]triphosphate (AMP[CH2]PP) increased peptide hydrolysis as well as ATP did. However, only ATP stimulated casein breakdown and only in the presence of Mg2+. Thus, nucleotide binding allows activation of the peptidase functions, but ATP hydrolysis seems necessary for enhanced degradation of proteins. The ATP effect on proteolysis was reversible and did not require ubiquitin. Sensitivity to ATP was labile, and with storage at 4 degrees C the enzyme became fully active in the absence of ATP or Mg2+. The ATP-activated form closely resembles the proteasome complex described previously, which did not show ATP dependence: both have molecular masses of 650 kDa, contain the same 8-10 subunits, and are precipitated by the same antibodies. A similar ATP-activated form was found in rabbit liver but not in rabbit reticulocytes. The proteasome seems to represent a ubiquitin-independent, ATP-stimulated proteolytic activity within nucleated mammalian cells.
New hybrid MAC-layer protocol for real-time bus networks (1994)

A hybrid group implicit token-CSMA/CD (GIT-CSMA/CD) access protocol for use in real-time bus networks is introduced. Network control is distributed over all nodes, thus eliminating the need for central switching. Operating features of the hybrid protocol are described together with its computer simulated performance evaluation. The results showing the delay-throughput characteristics are compared with CSMA/CD 1-persistent and token passing MAC-layer protocols. Optimum values for the number of stations comprising a group are obtained according to the requirements and specific conditions of each application. The implementation of the proposed protocol is based on the capabilities and the features of several existing CSMA/CD controllers and requires minor additional hardware and software.
Association of Polymorphisms in Monocyte Chemoattractant Protein-1 Promoter with Diabetic Kidney Failure in Korean Patients with Type 2 Diabetes Mellitus (2007)

Monocyte chemoattractant protein-1 (MCP-1) is suggested to be involved in the progression of diabetic nephropathy. We investigated the association of the -2518 A/G polymorphism in the MCP-1 gene with progressive kidney failure in Korean patients with type 2 diabetes mellitus (DM). We investigated -2518 A/G polymorphism of the MCP-1 gene in type 2 DM patients with progressive kidney failure (n=112) compared with matched type 2 DM patients without nephropathy (diabetic control, n=112) and healthy controls (n=230). The overall genotypic distribution of -2518 A/G in the MCP-1 gene was not different in patients with type 2 DM compared to healthy controls. Although the genotype was not significantly different between the patients with kidney failure and the diabetic control (p=0.07), the A allele was more frequent in patients with kidney failure than in DM controls (42.0 vs. 32.1%, p=0.03). The carriage of A allele was significantly associated with kidney failure (68.8 vs. 54.5%, OR 1.84, 95% CI 1.07-3.18). In logistic regression analysis, carriage of A allele retained a significant association with diabetic kidney failure. Our result shows that the -2518 A allele of the MCP-1 gene is associated with kidney failure in Korean patients with type 2 DM.
Structural variety in iridate oxides and hydroxides from hydrothermal synthesis (2011)

We report the results of an exploratory synthetic study of iridium-containing materials using hydrothermal methods from simple metal salts. Three alkali-earth iridium hydroxides are isolated as phase-pure samples and their structures examined by single-crystal or powder diffraction methods: each contains Ir(IV)-centred octahedra, isolated from each other and sharing bridging hydroxides or fluoride with alkali-earth (Ca, Sr or Ba) centres. One of these hydroxides, Ca2IrF(OH)6.OH, possesses a unique open structure, consisting of a positively-charged framework that has one-dimensional channels in which infinite chains of hydrogen-bonded hydroxide anions are encapsulated. The addition of hydrogen peroxide or sodium peroxide to otherwise identical hydrothermal reactions yields dense oxide materials in which iridium is found in an oxidation state between +4 and +5: the novel oxide Na0.8Sr2.2Ir3O10.1 has a KSbO3-type structure with an iridium oxidation state of +5, while the new pyrochlore (Na0.27Ca0.59)2Ir2O6·0.66H2O contains iridium with an average oxidation state close to +4.5. Our results illustrate the utility for hydrothermal synthesis in the discovery of novel complex structures that may be inaccessible using conventional high-temperature synthesis, with control of the metal oxidation state possible with judicious choice of reagents.
ChemInform Abstract: CHEMICAL AND PHARMACOLOGICAL RESEARCH ON PYRAN DERIVATIVES. NOTE VIII. SYNTHESIS OF 2‐(DIALKYLAMINO)‐7‐METHOXYCHROMONES AND THEIR DERIVATIVES (1977)

2-Dialkylamino-7-methoxychromones were prepared by reaction of a m-methoxyphenol with N,N-dialkylethoxycarbonylacetamides in the presence of phosphorus oxychloride. Treatment of such compounds with 57% hydriodic acid resulted in the formation of the corresponding 7-hydroxy derivatives. These latter, treated with dialkylamines and formaldehyde, were transformed into the 8-dialkylaminomethyl derivatives. On the other hand the reaction of 2-dialkylamino-7-methoxychromones with morpholine and formaldehyde, in the presence of acetic acid, led to the formation of the corresponding 3-morpholinomethyl derivatives. Pharmacological investigation showed that 2-dialkylamino-7-hydroxy-chromones were without effect, whereas all other compounds tested had a clear, but generally weak, CNS stimulant activity.
Photo induced gradient index lenses with W profile (2009)

Bicomponent composite material mixture and single beam photo polymerization method are used to create a micro lens with W -like distribution of refractive index; the flat analogy of the "Schmidt" lens. The choice of two key components of the mixture, which change their mutual miscibility after the photo polymerization of one of them, allows the creation of stable spatial modulation of the refractive index.