gebhart/patrepeval huggingface dataset:
Deconvolution of mass spectra measuredwith a non‐uniform detector array to give accurate ion abundances (2003)

Array detectors are under active development since they offer large improvements in the efficiency of mass spectrum measurements. High quality is always a requirement whether array detectors are used for ions, electrons, UV, x-rays, etc., but in mass spectrometry the very high accuracy frequently needed in ion abundance measurements for isotope ratios is unique. These demands necessitate modelling the measurement process and careful deconvolution of the measured data. A linear model in terms of matrix algebra is presented in which the incident spectrum (unknown) and the measured spectrum are represented by column matrices and the action of the detector array on the incident spectrum is represented by an experimentally measurable square 'A' matrix. Residual noise in this matrix can be minimized following a singular value decomposition procedure and its use in 'forward deconvolution' of measured spectra is discussed. The random error in the incident ion counts is accounted for after the deconvolution since this is not an error from the perspective of the detector. The microchannel plate electron multiplier gain distribution is an important feature of the deconvolution.
Enhanced efficiency of antiseptics with sustained release from clay nanotubes (2013)

Natural halloysite clay tubules were studied for their potential use as miniature biocompatible containers that can be loaded with antiseptics followed by their slow and controlled release. Brilliant green was loaded into 15 nm diameter halloysite lumen at 15 wt% and provided sustained release over six hours. Formation of a benzotriazole–copper coating on halloysite nanotubes allowed additional encapsulation providing for more sustained release from 50 to 200 hours. Antibacterial efficiency of the brilliant green in clay nanotubes was tested on Staphylococcus aureus cultures and antibacterial action extended up to 72 hours was demonstrated. Sustained release of amoxicillin and iodine from halloysite tubes was also demonstrated.
Production and Use of High Transient Magnetic Fields. I (1956)

Experiments involving pulsed magnetic fields of a half-megagauss and more are shown to be practical. Some basic concepts are developed regarding the construction of impact resistant solenoids and the selection of the appropriate power supply. Operation of various high-field magnets in the pulse range 50 to 10 000 μsec is discussed, and some techniques for associated solid state experiments are given. Magnetoresistance measurements up to 600 000 gauss have been made for germanium. Operation of a 175 000 gauss Helmholtz-type magnet for nuclear track plate work with the 95-Mev Harvard synchrocyclotron is described.
Defining an SOA for Stock Quote Management (2009)

Service-Oriented Architecture (SOA) has become a new paradigm for distributed applications development. SOA allows the integration of legacy systems with new development applications and to create more flexible and adaptive applications. Also, it allows decreasing implementation and maintenance times. SOA uses Web Services technology as a solution for business applications integration. This paper introduces a service-oriented architecture for solving integration problems with legacy systems of stock quote management on a sugar mill. Different levels of services of the proposed architecture are described. Also, a case of study is presented where the functionality of the proposed SOA is explained. Finally, we emphasize our contribution.
Synthesis and Reactivity of 1,2-Bis(di-<i>iso</i>-propylphosphino)benzene Nickel Complexes: A Study of Catalytic CO<sub>2</sub>–Ethylene Coupling (2018)

The utilization of renewable carbon dioxide resources in the production of commercial chemicals has been at the center of efforts to improve the sustainability of many widely used consumer products. The catalytic coupling of CO2 with ethylene to generate acrylates is one such avenue of research. Despite decades of investigations, catalytic CO2–ethylene coupling has only recently been experimentally demonstrated. The development of a new nickel-based catalyst, 1,2-bis(di-iso-propylphosphino)benzene nickel(0) 1,5-cyclooctadiene, for acrylate production is detailed here. The stoichiometric reactivity of the catalyst toward the CO2, ethylene, and base reagents, as well as the coordination chemistry of likely catalytic intermediates has been examined. Comparative catalytic experiments were used to identify the influence of commonly employed additives, such as metallic zinc and Lewis acidic salts, on the catalytic CO2–ethylene coupling reaction. In addition, catalytic comparisons of the 1,2-bis(di-iso-propylphosphino)benzene nickel(0) 1,5-cyclooctadiene species with a similar previously reported catalyst under newly developed conditions afforded turnover numbers greater than 400, an approximately 4-fold increase over the highest activity reported to date. Significantly, the catalytic trials reveal that small changes in the catalytic conditions and additives can have substantial effects on productivity and that these influences are not uniform with respect to catalyst platforms.
ChemInform Abstract: Total Syntheses of the Proposed Structures of Cuevaene A. (2010)

Abstract Both structures (I) are proved to be incorrect.
Noise reduction in TEM: Presenting a bandwidth- and sensitivity-optimized parallel recording setup and methods for adaptive synchronous detection (2012)

ABSTRACT The transient electromagnetic method (TEM) is a recognized tool for determining the subsurface resistivity structure over a wide depth interval. A key requirement for an accurate characterization of the shallow part of this interval is a sufficiently wideband receiver system. The maximum depth of investigation, on the other hand, is determined by the late-time signal-to-noise ratio (S/N). It has been demonstrated that the use of compact wideband receiver coils tends to deteriorate the late-time S/N due to their inherent low sensitivity to time-varying magnetic fields. To overcome this problem, we used a bandwidth- and sensitivity-optimized parallel recording setup using two separated receiver coils optimized for measuring the early- and late-time part of the transient signal, respectively. Using this setup, we experienced substantial improvements in the achievable depth of investigation while retaining shallow resolution. Further noise reduction may be obtained by adapting the applied synchronous detection measuring scheme to the local noise conditions. This is especially important when TEM are carried out in culturally developed areas, which is often the case for environmental investigations. Such soundings frequently suffer from inferior signal quality due to EM noise from local cultural sources. Comparing the frequency-domain filtering effect of the applied synchronous detection measuring scheme with the actual noise frequency content allowed us to evaluate the relative importance of the many sources of noise encountered in the field. Further improvements could be obtained by tailoring the applied synchronous detection to better reject specific noise frequencies through modification of the properties of time-gate integration and gate stacking.
A dual frequency resonator (2002)

A dual frequency resonator system operating at 74/37 MHz and using nested coaxial conductors for the dee stems in a proton/deuteron isotope production cyclotron is described. The design alternatives are discussed, basic computations presented, and compared with results from model measurements.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Neuronal Cdc2-like Kinase (Nclk) Binds and Phosphorylates the Retinoblastoma Protein (1997)

The tumor suppressor retinoblastoma protein (RB) plays a central role in cellular growth regulation, differentiation, and apoptosis. Phosphorylation of RB results in a consequent loss of its ability to inhibit cell cycle progression. However, how RB phosphorylation might be regulated in apoptotic or postmitotic cells, such as neurons, remains unclear. Here we report that neuronal Cdc2-like kinase (Nclk), composed of Cdk5 and a neuronal Cdk5 activator (p25(nck5a)), can bind and phosphorylate RB. Since RB has been shown recently to associate with D-type G1 cyclins and viral oncoproteins through a common peptide sequence motif of LXCXE, Nclk binding may be mediated by a related sequence motif (LXCXXE) found in p25(nck5a). We demonstrate (i) in vitro binding of bacterially expressed p25(nck5a) to a GST-RB fusion protein, (ii) coprecipitation of GST-RB and reconstituted Cdk5.p25(nck5a), and (iii) phosphorylation of GST-RB by bacterially expressed Cdk5.p25(nck5a) kinase and by Cdk5.p25(nck5a) kinase purified from bovine brain. Finally, we show that immunoprecipitation of RB from embryonic mouse brain homogenate results in the coprecipitation of Cdk5 and that Cdk5 kinase activity is maximal during late embryonic development, a period when programmed cell death of developing neurons is greatest. Taken together, these results suggest that Nclk can bind to and phosphorylate RB in vitro and in vivo. We infer that Nclk may play an important role in regulating the activity of RB in the brain, including perhaps in apoptosing neurons.
Using state machines to model the Ion Torrent sequencing process and to improve read error rates (2013)

Binaries and source code of FlowgramFixer are freely available at: http://www.cs.tau.ac.il/~davidgo5/flowgramfixer.html.
Production logic synthesis (1985)

Article Free Access Share on Production logic synthesis Authors: John Darringer IBM T.J. Watson Research Center, Yorktown Heights, New York IBM T.J. Watson Research Center, Yorktown Heights, New YorkView Profile , Daniel Brand IBM T.J. Watson Research Center, Yorktown Heights, New York IBM T.J. Watson Research Center, Yorktown Heights, New YorkView Profile , William H. Joyner IBM T.J. Watson Research Center, Yorktown Heights, New York IBM T.J. Watson Research Center, Yorktown Heights, New YorkView Profile , Louise Trevillyan IBM T.J. Watson Research Center, Yorktown Heights, New York IBM T.J. Watson Research Center, Yorktown Heights, New YorkView Profile , John V. Gerbi Data Systems Division, Poughkeepsie, New York Data Systems Division, Poughkeepsie, New YorkView Profile Authors Info & Claims CSC '85: Proceedings of the 1985 ACM thirteenth annual conference on Computer ScienceMarch 1985 Pages 13–16https://doi.org/10.1145/320599.320601Online:01 March 1985Publication History 0citation142DownloadsMetricsTotal Citations0Total Downloads142Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Thermal properties and flame retardancy of polycarbonate/hydroxyapatite nanocomposite (2008)

Abstract The thermal degradation of polycarbonate (PC) and polycarbonate/hydroxyapatite (PC/HAP) composite was investigated by the thermogravimetric analysis (TGA) and the decomposition activation energy was calculated by Kissinger method. It was found that the first step decomposition activation energy ( E a 1 ) was higher than that of pure PC while the second step decomposition ( E a 2 ) decreased a little. The limiting oxygen index (LOI) of PC/HAP composite with 0.5 wt % HAP reached 34. The carbon char of PC and PC/HAP composite after combustion was analyzed by scanning electron microscopy (SEM), X‐ray photoelectron spectroscopy (XPS), and flourier transform infrared spectroscopy (FTIR) and similar morphology, components, and the same functional groups were found in the char residues. Based on these results, it can be concluded that a low content of HAP in PC matrix can significantly improve the thermal properties and flame retardancy of the composite. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
Multisite comparison of methods for the quantitation of the surface expression of CD38 on CD8 T lymphocytes (2000)

We evaluated the effect of specimen processing variations and quantitation methods on quantitative determination of CD38 expression on CD8 T lymphocytes. Neither lysing reagent (ammonium chloride versus BD FACSlyse), fixation (paraformaldehyde versus no final fixation step), nor acquisition delay (acquisition within 6 h after fixation versus 24 h after fixation) had a significant effect on CD38 relative fluorescent intensity or CD38 quantitative estimates (RFI or antibodies bound per cell). The only significant difference in fluorescent intensity and CD38 antibodies bound per cell (ABC) was encountered when whole blood was held for 24 h prior to staining and fixation and then acquired after another 24-h hold. However, for all sample processing methods above, the CD4 biologic calibrator and QuantiBRITE bead methods gave significantly different estimates of CD38 intensity. In many cases, however, these differences are relatively small and were more pronounced in certain laboratories. We conclude that there is some flexibility in sample processing methods for quantitative CD38 determination; however, it is preferable for a laboratory to employ one method of fluorescence quantitation calculation consistently because small differences are detected between different methods. Cytometry (Comm. Clin. Cytometry) 42:174–179, 2000. © 2000 Wiley-Liss, Inc.
Extrudates of Starch‐Xanthan Gum Mixtures as Affected by Chemical Agents and Irradiation (1997)

ABSTRACT Mixtures of starch, xanthan gum and either polyvinyl alcohol, epichlorohydrin, valeric acid or adipoyl chloride were extruded. Properties of extrudates including apparent viscosity, water solubility, water absorption indices and exrudate expansion were measured for different proportions of xanthan gum, 70% amylose starch (with or without irradiation) and chemical agents. Extrusion with chemical agents and irradiation changed physical properties of both starch and xanthan gum. Expansions of extrudates were higher than that of starch. Viscosity of extrudates increased with xanthan gum concentration. The addition of 1% (w/w) polyvinyl alcohol had the greatest effect of the chemical agents. Irradiation increased the apparent viscosity of starchxanthan gum mixtures.
Serum Antibody Profile during Colonization of the Mouse Gut by <i>Candida albicans</i>: Relevance for Protection during Systemic Infection (2016)

Candida albicans is a commensal microorganism in the oral cavity and gastrointestinal and urogenital tracts of most individuals that acts as an opportunistic pathogen when the host immune response is reduced. Here, we established different immunocompetent murine models to analyze the antibody responses to the C. albicans proteome during commensalism, commensalism followed by infection, and infection (C, C+I, and I models, respectively). Serum anti-C. albicans IgG antibody levels were higher in colonized mice than in infected mice. The antibody responses during gut commensalism (up to 55 days of colonization) mainly focused on C. albicans proteins involved in stress response and metabolism and differed in both models of commensalism. Different serum IgG antibody-reactivity profiles were also found over time among the three murine models. C. albicans gut colonization protected mice from an intravenous lethal fungal challenge, emphasizing the benefits of fungal gut colonization. This work highlights the importance of fungal gut colonization for future immune prophylactic therapies.
Spin transport in GaAs (1998)

We present a spectroscopic method for studying spin transport in semiconductors. Our time-resolved experiments have an important implication for spin electronics as they show that spin-polarized electron drift is possible in semiconductors over typical device lengths in high electric fields. We demonstrate an almost complete conservation of the orientation of the electron spin during transport in GaAs over a distance as long as 4 μm and fields up to 6 kV/cm.
A fast and sensitive multiple sequence alignment algorithm (1989)

A two-step multiple alignment strategy is presented that allows rapid alignment of a set of homologous sequences and comparison of pre-aligned groups of sequences. Examples are given demonstrating the improvement in the quality of alignments when comparing entire groups instead of single sequences. The modular design of computer programs based on this algorithm allows for storage of aligned sequences and successive alignment of any number of sequences.
A 16ns 16K bipolar RAM (1983)

A 16ns 150mW ECL compatible static RAM will be described. Cell and die size of 569μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and 16.4mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> have been achieved with oxide-isolated poly silicon-walled emitter transistors.
Preparation and Properties of ${\hbox{Mg}}({\hbox{B}}_{1-{\rm x}}{\hbox{C}}_{\rm x})_{2}$ Using Carbon Chemical Vapor Coated Boron (2007)

Promising initial results on bulk Mg(B <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> ) <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> prepared with carbon doped boron are presented. Carbon doping is achieved by reaction of ethylene gas on boron powder using a stainless steel tube furnace, a technique suitable for industrial scale processing. The nominal amount of doping was controlled by varying the reaction time with a fixed volume of ethylene gas, and the actual carbon uptake was determined by weight change after the reaction. The amount of carbon substitution x in the Mg(B <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> ) <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> was found using the angular shift in the (100) X-ray reflection. Carbon substitution by the full nominal content in the C doped precursor boron was obtained for doping up to 7.2 at%, as shown by a o-axis compression consistent with that of carbon doped single crystals. The critical current density of the 4 at% C doped sample for temperatures at 20-30 K and fields up to 4 T, relevant to high temperature applications, was significantly higher than those in the published literature. The J <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C</sub> of a 10 wt% nano-SiC doped sample, used as a comparative benchmark, was found to be lower than the C doped sample at field below 2 T, but to reduce slower at higher fields. Structure analysis of the SiC doped sample revealed a coexistence of two C substitution levels of 2.25% at and 5.25% at.
Heart Disease and Stroke Statistics—2021 Update (2021)

The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.
Optical recording on microscopically textured surfaces (1982)

Textured surfaces consisting of submicron columns or cones have been formed in metals, semiconductors, and insulators. This structured surface morphology forms a graded-index-matching layer that reduces reflection of visible light to as low as 0.1 %. The optical properties of this surface can be permanently altered on a ≲ 1- μ m size scale by irradiation with a focused low-power laser beam. The light energy transforms the optically absorbing textured surface to a nonabsorbing smooth one by melting the structures or initiating a chemical reaction.
FeCl<sub>2</sub>-CatalyzedAminobromination of Alkenes Using Amides or Sulfonamidesand NBS as the Nitrogen and Bromine Sources (2008)

We have developed a convenient and efficient iron-catalyzed aminobromination of the alkenes using inexpensive FeCl2 as the catalyst, amides/sulfonamides and NBS as the nitrogen and bromine sources, respectively, under mild conditions.
Wireless Integrated Microsystems: Coming Breakthroughs in Health Care (2006)

Wireless integrated microsystems, merging micropower circuits, wireless interfaces, hermetic wafer-level packaging, and MEMS are poised to provide breakthroughs in health care. While cochlear microsystems have restored functional hearing to the deaf and deep brain stimulation is remarkably successful in suppressing Parkinson's tremor, retinal implants for the blind, cortical prostheses for paralysis, and other devices are also emerging, along with systems that could revolutionize our understanding of the brain. The tissue interface, device/circuit challenges, and packaging are examined along with future needs
Fundamentals of Robotics: Linking Perception to Action (2003)

Introduction to Robotics Motion of Rigid Body Mechanical System of Robot Electromechanical System of Robot Control System of Robot Information System of Robot Visual Sensory System of Robot Visual Perception System of Robot Decision-Making System of Robot.
Reduced Cx43 Expression Triggers Increased Fibrosis Due to Enhanced Fibroblast Activity (2012)

Reduced cellular coupling results in more excessive collagen deposition during aging or pressure overload in mice due to enhanced fibroblast activity, leading to increased conduction in homogeneity and proarrhythmia.
Stability of traveling-wave solutions for a Schrodinger system with power-type nonlinearities (2014)

In this article, we consider the Schrodinger system with powertype nonlinearities, (Formula presented) where j = 1,...,m, uj are complex-valued functions of (x, t) 2 RN+1, a, b are real numbers. It is shown that when b > 0, and a + (m - 1)b > 0, for a certain range of p, traveling-wave solutions of this system exist, and are orbitally stable.
Metal Oxide Laser Ionization Mass Spectrometry Imaging (MOLI MSI) Using Cerium(IV) Oxide (2019)

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a powerful technique for spatially resolved metabolomics. A variation on MALDI, termed metal oxide laser ionization (MOLI), capitalizes on the unique property of cerium(IV) oxide (CeO<sub>2</sub>) to induce laser-catalyzed fatty acyl cleavage from lipids and has been utilized for bacterial identification. In this study, we present the development and utilization of CeO<sub>2</sub> as an MSI catalyst. The method was developed using a MALDI TOF instrument in negative ion mode, equipped with a high frequency laser. Instrument parameters for MOLI MS fatty acid catalysis with CeO<sub>2</sub> were optimized with phospholipid standards and fatty acid catalysis was confirmed using lipid extracts from reference bacterial strains, and sample preparation was optimized using mouse brain tissue. MOLI MSI was applied to the imaging of normal mouse brain revealing differentiable fatty acyl pools in myelinated and nonmyelinated regions. Similarly, MOLI MSI showed distinct fatty acyl composition in tumor regions of a patient derived xenograft mouse model of glioblastoma. To assess the potential of MOLI MSI to detect pathogens directly from tissue, a pseudoinfection model was prepared by spotting Escherichia coli lipid extracts on mouse brain tissue sections and imaged by MOLI MSI. The spotted regions were molecularly resolved from the supporting mouse brain tissue by the diagnostic odd-chained fatty acids and reflected control bacterial MOLI MS signatures. We describe MOLI MSI for the first time and highlight its potential for spatially resolved fatty acyl analysis, characterization of fatty acyl composition in tumors, and its potential for pathogen detection directly from tissue.