gebhart/patrepeval huggingface dataset:
[Use of an integrated assessment of the level of medical care of patients with cardiovascular diseases at a central district hospital]. (1990)

An integrated evaluation is presented of the quality of level medical services in patients with cardiovascular diseases in in- and outpatients according to a method developed at the Leningrad Research Institute of Cardiology. Results of the analysis allowed to work out measures for removing drawbacks in the therapeutic-diagnostic process, organization and methodical work. Implementation of these methods improved the quality of medical services to this category of patients.
ANALYSIS OF NOISE ABATEMENT DUE TO ABSORPTIVE DEVICE AT THE TOP OF HIGHWAY NOISE BARRIERS BY BOUNDARY ELEMENT METHOD (1997)

道路遮音壁先端に設置して騒音低減効果を高める音響装置 (ノイズリデューサー) について, その設置効果の解析を波動音響に基づく理論計算によって行った. 理論計算は二次元境界要素法を用いて行い, その設置効果の特徴を明らかにするとともに, 現地実測による測定値ともよい一致が得られることを示した.
Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS (1993)

Patients with AIDS often experience recurrent infections with varicella-zoster virus (VZV) requiring repeated or prolonged treatment with acyclovir (ACV), which may lead to the development of ACV resistance. The ACV resistance of isolates recovered from such patients is associated with diminished VZV thymidine kinase (TK) function. We determined the nucleotide sequences of the TK genes of 12 ACV-resistant VZV strains purified from nine patients with AIDS. Five VZV strains contained nucleotide deletions in their TK genes, introducing a premature termination codon which is expected to result in the production of a truncated protein. No detectable full-length TK protein could be immunoprecipitated from extracts of cells infected with these virus strains. These TK-deficient strains were cross resistant to the TK-dependent antiviral agents ACV, 9-(4-hydroxy-3-hydroxymethylbutyl-yl)guanine (penciclovir), and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl) uracil (BVaraU). The remaining seven strains each contained a nucleotide change that resulted in an amino acid substitution in the TK protein. These substitutions occurred throughout the TK protein, namely, in the ATP-binding site, the nucleoside-binding site, between the two binding sites, and at the carboxy terminus of the protein. We determined the effects of these mutations on the stability of TK protein expression in virus-infected cells and on the sensitivity of mutants to the TK-dependent antiviral agents ACV, BVaraU, and penciclovir.
Comparative Analysis of the Regulation of Expression and Structures of Two Evolutionarily Divergent Genes for Δ1-Pyrroline-5-Carboxylate Synthetase from Tomato (1998)

We isolated two tomato (Lycopersicon esculentum) cDNA clones, tomPRO1 and tomPRO2, specifying Delta1-pyrroline-5-carboxylate synthetase (P5CS), the first enzyme of proline (Pro) biosynthesis. tomPRO1 is unusual because it resembles prokaryotic polycistronic operons (M.G. García-Ríos, T. Fujita, P.C. LaRosa, R.D. Locy, J.M. Clithero, R.A. Bressan, L.N. Csonka [1997] Proc Natl Acad Sci USA 94: 8249-8254), whereas tomPRO2 encodes a full-length P5CS. We analyzed the accumulation of Pro and the tomPRO1 and tomPRO2 messages in response to NaCl stress and developmental signals. Treatment with 200 mM NaCl resulted in a >60-fold increase in Pro levels in roots and leaves. However, there was a <3-fold increase in the accumulation of the tomPRO2 message and no detectable induction in the level of the tomPRO1 message in response to NaCl stress. Although pollen contained approximately 100-fold higher levels of Pro than other plant tissues, there was no detectable increase in the level of either message in pollen. We conclude that transcriptional regulation of these genes for P5CS is probably not important for the osmotic or pollen-specific regulation of Pro synthesis in tomato. Using restriction fragment-length polymorphism mapping, we determined the locations of tomPRO1 and tomPRO2 loci in the tomato nuclear genome. Sequence comparison suggested that tomPRO1 is similar to prokaryotic P5CS loci, whereas tomPRO2 is closely related to other eukaryotic P5CS genes.
Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop (2013)

Paternal duplications of chromosome 6q24, a region that contains the imprinted PLAGL1 and HYMAI transcripts, are associated with transient neonatal diabetes mellitus. A common feature of imprinted genes is that they tend to cluster together, presumably as a result of sharing common cis-acting regulatory elements. To determine the extent of this imprinted cluster in human and mouse, we have undertaken a systematic analysis of allelic expression and DNA methylation of the genes mapping within an ∼1.4-Mb region flanking PLAGL1/Plagl1. We confirm that all nine neighbouring genes are biallelically expressed in both species. In human we identify two novel paternally expressed PLAGL1 coding transcripts that originate from unique promoter regions. Chromatin immunoprecipitation for CTCF and the cohesin subunits RAD21 and SMC3 reveals evolutionarily conserved binding sites within unmethylated regions ∼5 kb downstream of the PLAGL1 differentially methylated region and within the PLAGL1 3' untranslated region (UTR). Higher-order chromatin looping occurs between these regions in both expressing and non-expressing tissues, forming a non-allelic chromatin loop around the PLAGL1/Plagl1 gene. In placenta and brain tissues, we identify an additional interaction between the PLAGL1 P3/P4 promoters and the unmethylated element downstream of the PLAGL1 differentially methylated region that we propose facilitates imprinted expression of these alternative isoforms.
Characterization of Supercapacitors Using Singlewalled Carbon Nanotube Electrodes (2000)

The key factors determining the performance of supercapacitors using singlewalled CNT elec-trodes were investigated. We obtained a maximum specific capacitance of 180 F/g and a measured power density of 20 kW/kg at the energy density of 7 Wh/kg in a solution of 7.5 N KOH. The specific surface area and the specific capacitance increase with increasing annealing temperatures of the sample. It was found that most of the BET surface area of the electrode contributes to the theoretically estimated specific capacitance. Minimization of the contact resistance is independent of the specific capacitance but directly related to the maximization of the power density. I.
A general theory for deadlock avoidance in wormhole-routed networks (1998)

Most machines of the last generation of distributed memory parallel computers possess specific routers which are used to exchange messages between nonneighboring nodes in the network. Among the several technologies, wormhole routing is usually preferred because it allows low channel-setup time and reduces the dependency between latency and internode distance. However, wormhole routing is very susceptible to deadlock because messages are allowed to hold many resources while requesting others. Therefore, designing deadlock-free routing algorithms using few hardware facilities is a major problem for wormhole-routed networks. In this paper, we describe a general theoretical framework for the study of deadlock-free routing functions. We give a general definition of what can be a routing function. This definition captures many specific definitions of the literature (e.g., vertex dependent, input-dependent, source-dependent, path-dependent etc.). Using our definition, we give a necessary and sufficient condition which characterizes deadlock-free routing functions. Our theory embraces, at a high level, most of the theories related to deadlock avoidance in wormhole-routed networks previously derived in the literature. In particular, it applies not only to one-to-one routing, but also to one-to-many routing. The latter paradigm is used to solve the multicast problem with the path-based or tree-based facility.
TESTING OF AFTERMARKET PRODUCTS (1984)

Two automotive aftermarket products, an Oil Additive and a Specialized Jumper Cable were tested. The oil additive was tested to determine its effects on fuel economy, horsepower, and exhaust emissions while the specialized jumper cable was compared to the operation of a traditional jumper cable. The results indicated that the oil additive had no significant effect on fuel economy, horse-power, or exhaust emissions, and that the specialized jumper cables did not match the performance of a traditional jumper cable.
Understanding and minimizing ground bounce during mode transition of power gating structures (2003)

We introduce and analyze the ground bounce due to power mode transition in power gating structures. To reduce the ground bounce, we propose novel power gating structures in which sleep transistors are turned on in a non-uniform stepwise manner. Our power gating structures reduce the magnitude of peak current and voltage glitches in the power distribution network as well as the minimum time required to stabilize power and ground. Experimental simulation results with PowerSpice fixtured in a package model demonstrate the effectiveness of the proposed power gate switching noise reduction techniques.
Cloning by somatic cell nuclear transfer (1998)

The birth of the first cloned mammals, produced by the introduction of somatic cell nuclei into enucleated oocytes, was an impressive and surprising development.(1) Although the ethical debate has been intense, the important scientific questions raised by this work have been inadequately discussed and are still unresolved. In this essay we address three questions about nuclear transplantation in the eggs of mice and domestic animals. First, why were the recent experiments on somatic cell cloning successful, when so many others have failed? Second, were these exceptional cases, or is somatic cloning now open to all? Third, what are the future possibilities for increasing the efficiency and wider applicability of the cloning process? BioEssays 20:847–851, 1998. © 1998 John Wiley & Sons, Inc.
Phononic Frequency Combs in Stand-Alone Piezoelectric Resonators (2018)

This work reports on the generation and frequency tuning mechanisms of resonant-based phononic frequency combs. The reported mechanical frequency combs are realized in an integrated standalone piezoelectric platform and are excited via non-degenerate parametric pumping. Two flexural resonance modes of a thin Aluminum Nitride (AlN)-on-silicon circular membrane are targeted due to their low onset of nonlinearity and excited simultaneously. When the resonator is pumped with a single tone at a frequency close to the sum of the two mechanical modes, phononic frequency combs are generated close to each mechanical mode, under certain and repeatable pump frequency and power conditions. The phononic combs consist of a set of equally-distanced phase-coherent spectral lines; we demonstrate such combs centered around 6 MHz, with a tunable spacing of around 55 kHz, corresponding to the u <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> resonance mode of the circular membrane. The center frequency and frequency spacing of the comb can be tuned by tuning the pump frequency and amplitude. We take advantage of the mode coupling between two high- Q resonance modes in the same acoustic cavity, and demonstrate the smallest piezoelectric frequency comb, with a 30 μm diameter circular footprint, which requires a very low threshold power of only -4 dBm to excite a fine-tooth comb.
Cellular and Molecular Regulation of Skeletal Muscle Side Population Cells (2004)

Muscle progenitor cells (satellite cells) function in the maintenance and repair of adult skeletal muscle. Side population (SP) cells are enriched in repopulating activity and also reside in adult skeletal muscle. In this study, we observed that Abcg2 is a determinant of the SP cell phenotype. Using reverse transcription polymerase chain reaction and immunohistochemical techniques, we localized Abcg2-expressing cells in the interstitium and in close approximation to the vasculature of adult skeletal muscle. Muscle SP cells are able to differentiate into myotubes and increase in number after cardiotoxin-induced muscle injury. Similar to myogenic progenitor cells, muscle SP cells express Foxk1 and are decreased in number in Foxk1 mutant skeletal muscle. Using emerging technologies, we examine the molecular signature of muscle SP cells from normal, injured, and Foxk1 mutant skeletal muscle to define common and distinct molecular programs. We propose that muscle SP cells are progenitor cells that participate in repair and regeneration of adult skeletal muscle.
An Extremely Active Solid Acid Catalyst, Nafion Resin/Silica Composite, for the Friedel−Crafts Benzylation of Benzene and <i>p</i>-Xylene with Benzyl Alcohol (1997)

Nafion resin, a recently developed Nafion resin/silica composite, and triflic acid are very effective catalysts for the Friedel−Crafts benzylation of benzene (at 80 °C) and p-xylene (at 100 °C) with p-methylbenzyl alcohol under ambient pressure. The composite is nearly 2 orders of magnitude more active than plain Nafion resin beads and even more active than the strong triflic acid based on the same amount of acid groups in the catalysts. The commercial Amberlyst-15 resin catalyst and p-toluenesulfonic acid (p-TSA) are inactive catalysts. Flowing nitrogen through the reactor to carry out the byproduct water was found to be very beneficial for driving the benzylation reaction to completion.
Effect of Muscadine Grape Seed Supplementation on Vascular Function in Subjects with or at Risk for Cardiovascular Disease: A Randomized Crossover Trial (2010)

Four weeks of muscadine grape seed supplementation in subjects with increased cardiovascular risk did not produce a statistically significant increase in brachial flow-mediated vasodilation or a significant change in other biomarkers of inflammation, lipid peroxidation, or antioxidant capacity. However, the muscadine grape seed supplement did result in a significant increase in resting brachial diameter. The clinical significance of the effect on resting diameter is not yet established. More research is warranted to fully characterize the vascular effects of this and other grape-derived nutritional supplements and to determine whether these vascular effects translate into important clinical benefits.
Exploring New Perspectives in Network Music Performance: The DIAMOUSES Framework (2010)

June 01 2010 Exploring New Perspectives in Network Music Performance: The DIAMOUSES Framework Chrisoula Alexandraki, Chrisoula Alexandraki *Department of Music Technology and Acoustics, Technological Educational Institute of Crete, E. Daskalaki 1, Perivolia 74100, Rethymnon, Crete, Greece. chrisoula@staff.teicrete.gr Search for other works by this author on: This Site Google Scholar Demosthenes Akoumianakis Demosthenes Akoumianakis *Department of Music Technology and Acoustics, Technological Educational Institute of Crete, E. Daskalaki 1, Perivolia 74100, Rethymnon, Crete, Greece. chrisoula@staff.teicrete.gr**Department of Applied Informatics and Multimedia, Technological Educational Institute of Crete, Estavromenos 71500, Heraklion, Crete, Greece. da@epp.teicrete.gr Search for other works by this author on: This Site Google Scholar Author and Article Information Chrisoula Alexandraki *Department of Music Technology and Acoustics, Technological Educational Institute of Crete, E. Daskalaki 1, Perivolia 74100, Rethymnon, Crete, Greece. chrisoula@staff.teicrete.gr Demosthenes Akoumianakis *Department of Music Technology and Acoustics, Technological Educational Institute of Crete, E. Daskalaki 1, Perivolia 74100, Rethymnon, Crete, Greece. chrisoula@staff.teicrete.gr**Department of Applied Informatics and Multimedia, Technological Educational Institute of Crete, Estavromenos 71500, Heraklion, Crete, Greece. da@epp.teicrete.gr Online ISSN: 1531-5169 Print ISSN: 0148-9267 © 2010 Massachusetts Institute of Technology.2010 Computer Music Journal (2010) 34 (2): 66–83. https://doi.org/10.1162/comj.2010.34.2.66 Connected Content A correction has been published: Erratum (In CMJ 34:2 (Summer 2010), pp. 1, 3, and 66–83, author Demosthenes Akoumianakis's surname was misspelled as Akoumanakis, except in the article's list of references and in the citation on p. 75) Cite Icon Cite Permissions Share Icon Share Facebook Twitter LinkedIn MailTo Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Search Site Citation Chrisoula Alexandraki, Demosthenes Akoumianakis; Exploring New Perspectives in Network Music Performance: The DIAMOUSES Framework. Computer Music Journal 2010; 34 (2): 66–83. doi: https://doi.org/10.1162/comj.2010.34.2.66 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsComputer Music Journal Search Advanced Search This content is only available as a PDF. © 2010 Massachusetts Institute of Technology.2010 Article PDF first page preview Close Modal You do not currently have access to this content.
CD4+ T Lymphocytes Are Not Necessary for the Acute Rejection of Vascularized Mouse Lung Transplants (2008)

Acute rejection continues to present a major obstacle to successful lung transplantation. Although CD4(+) T lymphocytes are critical for the rejection of some solid organ grafts, the role of CD4(+) T cells in the rejection of lung allografts is largely unknown. In this study, we demonstrate in a novel model of orthotopic vascularized mouse lung transplantation that acute rejection of lung allografts is independent of CD4(+) T cell-mediated allorecognition pathways. CD4(+) T cell-independent rejection occurs in the absence of donor-derived graft-resident hematopoietic APCs. Furthermore, blockade of the CD28/B7 costimulatory pathways attenuates acute lung allograft rejection in the absence of CD4(+) T cells, but does not delay acute rejection when CD4(+) T cells are present. Our results provide new mechanistic insight into the acute rejection of lung allografts and highlight the importance of identifying differences in pathways that regulate the rejection of various organs.
Low temperature cofired ceramic (LTCC) ridge waveguide multiplexers (2002)

Compact H-plane ridge waveguide multiplexers and their transitions for LTCC applications are described. Full wave modeling based design procedure was developed. X-band single ridge waveguide contiguous diplexers, triplexers and their transitions were successfully designed and embedded in the LTCC substrate. Good experimental results were obtained, which demonstrated feasibility of integrating 3D filtering structure with planar microwave integrated circuits (MIC) in the multilayer substrates.
Hypoglycemic Agents—Past and Present (1959)

Journal Article Hypoglycemic Agents—Past and Present Get access Israel S Kleiner Israel S Kleiner Professor of Biochemistry, New York Medical College, Flower and Fifth Avenue Hospitals, New York 29, N. Y Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 5, Issue 2, 1 April 1959, Pages 79–99, https://doi.org/10.1093/clinchem/5.2.79 Published: 01 April 1959
Group-based user pairing for virtual MIMO in LTE (2007)

配对方法的一个用户被建议改进虚拟多重输入的产量获得在 3G 的多重输出(虚拟 MIMO ) 长期的进化(LTE ) 。在这研究采取的途径分开了配对进四个步骤的用户：1 ) 用户根据他们的 signal-to-noise 比率(SNR ) 被划分成二个组，并且不同用户配对度量标准为每个组被建议；2 ) 调度程序为按一条给定的规则播送选择一个用户；3 ) 调度程序在每个组在配对的候选人找选择用户；4 ) 调度程序由使用一个边缘的实用程序函数从合作组和转线路组候选人选择最后的配对用户，平衡公平和效率。方法能与高 SNR 改进用户的产量，并且与低 SNR 为用户保证公平，因此它能在 3G LTE 系统被使用。文章提供理论分析和模拟结果支持这个想法。
Sulfur Resistance of Pt‐W Catalysts (2012)

The sulfur resistance of low‐loaded monometallic Pt catalysts and bimetallic Pt‐W catalysts during the partial selective hydrogenation of styrene, a model compound of Pygas streams, was studied. The effect of metal impregnation sequence on the activity and selectivity was also evaluated. Catalysts were characterized by ICP, TPR, XRD, and XPS techniques. Catalytic tests with sulfur‐free and sulfur‐doped feeds were performed. All catalysts showed high selectivities (>98%) to ethylbenzene. Activity differences between the catalysts were mainly attributed to electronic effects due to the presence of different electron‐rich species of Pt 0 and electron‐deficient species of Pt δ + . Pt 0 promotes the cleavage of H 2 while Pt δ + the adsorption of styrene. The catalyst successively impregnated with W and Pt (WPt/Al) was more active and sulfur resistant than the catalyst prepared with an inverse impregnation order (PtW/Al). The higher poison resistance of WPt/Al was attributed to both steric and electronic effects.
On the stability of rivulet flow (1990)

The aim of the present work is to investigate the existence regions of the different flow patterns exhibited by a liquid flowing down an inclined plane for a wide range of physical properties of the fluid (particularly surface tension and viscosity which were found to have the greatest influence). A model that predicts the decay frequency of oscillating or pendulum rivulets is presented. From this model, a stability criterion for the onset of oscillating rivulet flow is derived. Although the model does not contain any freely adjustable parameters, it shows good agreement with experimental measurements of rivulet decay frequency and of the transition point to pendulum rivulet. The transitions between different flow regimes are expected to cause drastic changes in heat and mass transfer rates between the liquid and the solid surface or between the liquid and the surrounding gaseous phase.
Genetic analysis of rice domestication syndrome with the wild annual species, <i>Oryza nivara</i> (2006)

With a small and sequenced genome, rice provides an excellent system for studying the genetics of cereal domestication. We conducted a quantitative trait locus (QTL) analysis of key domestication traits using an F2 population derived from a cross between the cultivated rice, Oryza sativa, and the annual wild species, O. nivara. We found that the QTL of large phenotypic effects were targeted by domestication selection for effective harvest and planting, including a reduction in seed shattering and seed dormancy and the synchronization of seed maturation. Selection for higher yield was probably responsible for the fixation of mutations at a cluster of QTL on chromosome 7 and a few other chromosomal locations that could have substantially improved plant architecture and panicle structure, resulting in fewer erect tillers and longer and more highly branched panicles in cultivated rice. In comparison with the wild perennial species, O. rufipogon, rice domestication from O. nivara would have involved QTL with a greater degree of chromosomal co-localization and required little genetic change associated with life history or mating system transitions. The genetic analyses of domestication traits with both wild relatives will open opportunities for the improvement of rice cultivars utilizing natural germplasm.