gebhart/patrepeval huggingface dataset:
<scp>XI</scp>. Yeast sequencing reports. The sequence of a 12kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP‐glucose pyrophosphorylase from potato (1992)

We report the sequence of a 12,399 bp DNA fragment from the left arm of Saccharomyces cerevisiae chromosome XI. This fragment is located between the genetic loci mif2 and mak11. We have detected five new open reading frames (ORFs) longer than 300 bp provisionally called YKL248 to YKL252. One of them, YKL248 encodes a homolog of the UDP-glucose pyrophosphorylase from potato. The product of YKL251 contains the consensus for zinc binding proteins, similar to those of a number of fungal transcriptional activators. The three other ORFs do not show significant homology to known protein.
High-Temperature Molten-Salt Lubricated Hydrodynamic Journal Bearings (1961)

Hydrodynamic lubrication of journal-type bearings was demonstrated over the temperature range of 1200–1500 F with molten-salt 130 (62 LiF-37 BeF2-1 UF4, mole %). A number of demonstration tests were performed to investigate hydrodynamic lubrication at steady-state operating conditions, the ability to stop and restart rotation of the journal, performance over a range of Sommerfeld number from 0.009 to 2.0, thermal stability of the bearing material, and bearing configurations for sustaining unidirectional and bidirectional radial loading. These tests comprise 3900 hr of operation at high temperatures. As examples of the tests, one covered a period of 1000 hr at steady-state conditions and another covered a period of 272 hr, wherein 260 start-stop operations were performed. All the test bearings and journals were constructed of a nickel-molybdenum alloy. A molten-salt bearing was applied to a vertical centrifugal pump, and performance was satisfactory following initial tests wherein it was found that the bearing was being starved.
Probabilities of identity-by-descent patterns in sibships when the parents are not genotyped (1997)

An assumption-free algorithm has been applied to compute the probabilities of all possible identity-by-descent (IBD) configurations when the parents have not been genotyped. These probabilities can be used to determine the amount of information that a particular sibship will bring to a nonparametric linkage analysis. It is shown that the number of possible configurations can be extremely large even when the markers are closely spaced and are rather polymorphic. Further, it is not always possible to reduce this number to a manageable one simply by consideration of the relative probabilities of the configurations.
Amylose-wrapped luminescent conjugated polymers (2008)

Highly luminescent inclusion complexes consisting of poly(para-phenylene) (PPP) or poly(4,4'-diphenylene-vinylene) (PDV) in the helical cavity of amylose have been synthesised, structurally characterised by nuclear Overhauser spectroscopy and used to fabricate electroluminescent light-emitting diodes.
Metabolism of Sphingosine Bases, XIX. On the Origin of Phytosphingosine (4<i>D</i>-Hydroxysphinganine) in Mammalian Tissues (1972)

Article Metabolism of Sphingosine Bases, XIX. On the Origin of Phytosphingosine (4D-Hydroxysphinganine) in Mammalian Tissues was published on January 1, 1972 in the journal Biological Chemistry (volume 353, issue 1).
Nuclear Magnetic Interactions in the HF Molecule (1956)

Magnetic relaxation times of hydrogen and fluorine in anhydrous hydrofluoric acid cannot be accounted for on the assumption of a pure dipole-dipole interaction between the hydrogen and the fluorine nuclei in the same molecule. However, the introduction, in the Hamiltonian, of a scalar term AI·S resulting from the indirect electron-coupled interaction between the two nuclei removes all the discrepancies between the calculated and observed decay times. Although the splitting due to this scalar term is smeared out by the rapid chemical exchange of the protons with the traces of water present in the acid, the nuclear Overhauser effect provides the extra parameter required to separate the dipole-dipole interaction from the scalar interaction and to calculate separately the scalar splitting and the exchange rate of the protons. The value obtained for the splitting is A/h=615 cps. The same method has been applied to investigate the structure of the HF molecule in solutions. The experimental results can be explained qualitatively by the following picture: (a) The fluorine nuclei form long chains that move more slowly than the Larmor frequency of fluorine. (b) The chemical exchange with the relatively large quantity of water present makes the motion of the hydrogen nuclei fast with respect to the hydrogen Larmor frequency. The results are: Long relaxation times for hydrogen with T1 and T2 equal, relatively short relaxation times for fluorine resonance, with T2 shorter than T1. Solutions of salts of hydrofluoric acid (KF) show the same character as solutions of the acid.
Joseph Smith's Cooperstown Bible: The Historical Context of the Bible Used in the Joseph Smith Translation (2001)

In 1828, the H. and E. Phinney Company in Cooperstown, New York, published a quarto-size edition of the King James Bible. This is the version that Joseph Smith, founder of The Church of Jesus Christ of Latter-day Saints, used in his work when he created a new translation of the Bible. Here the author examines Joseph Smith's marked-up copy of the Phinney Bible as an artifact important to Mormonism. Some of Smith's corrections and additions appear in footnotes of the Bible that Mormons use today. The author notes that the Phinney Bible's updated language is more modern than the version of the Bible Latter-day Saints officially use (the King James), and the modernization may or may not have influenced Joseph Smith's word choice in creating his translation. The author also gives biographical information on the Phinneys, describes how their Bible may have made its way into Joseph Smith's hands, briefly traces the history of the English Bible in America, and describes the printing process employed by the Phinneys.
Effects of Hexanal, <i>trans</i>-2-Hexenal, and Storage Temperature on Shelf Life of Fresh Sliced Apples (2000)

In this paper, the effects of hexanal and trans-2-hexenal, which are both natural molecules characterizing apple aroma, on the microbial population and on color retention of fresh sliced apples were evaluated. In particular, a central composite design (CCD) was developed to assess the individual and interactive effects of the chosen volatile molecules and storage temperatures on (i) the growth of the naturally occurring microflora, (ii) the evolution over time of an inoculated spoilage yeast (Pichia subpelliculosa), and (iii) the enzymatic browning reaction in minimally processed apples. The inclusion of hexanal and trans-2-hexenal in the storage atmosphere of apple slices determined a significant extension of shelf life also when P. subpelliculosa was inoculated at levels of 10(3) colony-forming units/g and abusive storage temperatures were used. In fact, the presence of these molecules in the packaging atmospheres considerably prolonged the lag phases of the inoculated yeast and reduced the growth potential of naturally occurring bacteria. Moreover, the addition to the modified atmosphere of low levels of the hexanal increased the color stability of the products up to 16 days.
A comparison of the influence of <i>Streptococcus lactis</i> and <i>Str. cremoris</i> starters on the flavour of Cheddar cheese (1961)

Summary Comparable cheeses were made using single strains of Streptococcus cremoris and Str. lactis as starters. The three Str. lactis strains imparted a characteristic rather abnormal flavour to the cheese, whereas the three strains of Str. cremoris all gave cheeses of normal flavour. The abnormal flavour caused by the lactis cultures increased in intensity as ripening proceeded, and differed slightly from strain to strain. Bacteriophage usually developed slightly in the whey and in the curd during the manufacturing process, but never to such a degree as to delay acid production unduly. The extent of phage development did not have a significant influence on cheese flavour. All the lactis strains survived in much larger numbers in the cheese than the cremoris strains. The simplest explanation of the data is that the ‘lactis’ flavour was a direct effect, due to flavour substances produced by the Str. lactis cells present in the young cheese.
Indirect Employment and Income Distribution Impacts of Investment Programs (1980)

Private and public investment programs are often implemented without adequate knowledge of their employment or income distribution impacts. For example, although numerous studies have been done on the environmental and economic efficiency aspects of electricity generation alternatives, relatively little is known of who will benefit and by how much.
The denudation history of the onshore continental margin of SE Brazil inferred from apatite fission track data (1994)

A suite of 68 new apatite fission track analysis results from the onshore rift margin in southeast Brazil are presented. Some of the results reflect resetting related to the eruption of the Paraná continental flood basalt (∼130 Ma), and four others are directly related to Late Cretaceous magmatism (∼80 Ma). The majority of the results were obtained from Precambrian basement rocks and sediments from the Paraná Basin. The fission track ages broadly increase inland from 60–90 Ma on the coastal plain to >300 Ma in the continental hinterland. The track length distributions show a characteristic trend, being negatively skewed at the coast and showing increasing bimodality inland, except for the oldest samples which are more unimodal. These trends do not reflect rift‐related heating and resetting but are the result of protracted denudation since the opening of the South Atlantic. The results are consistent with more than 3 km of exhumation on the coastal plain but little more than 1 km in the hinterland. The topographic morphology in the northern region of the study area is complex and is clearly influenced by structure and bedrock lithology. For the region further south, model calculations of the isostatic response to the denudation suggest that isostatic rebound makes a minor contribution to the long‐wavelength topography, unless the flexural rigidity is more than 10 25 N m. In this case the initial elevation of the rift margin would need to be >2.5 km in order to accommodate the amount of denudation inferred from the fission track data. However, it is possible that the effective flexural rigidity varies across the margin, becoming greater in the continental interior. Alternatively, the broad scale wavelength topography may be the result of magmatic underplating related to the Paraná continental flood basalt event. If so, estimates of the volume of magma generated would need to be revised upward by as much as a factor of 5.
Field-split parallel architecture for high performance multi-match packet classification using FPGAs (2009)

Multi-match packet classification is a critical function in network intrusion detection systems (NIDS), where all matching rules for a packet need to be reported. Most of the previous work is based on ternary content addressable memories (TCAMs) which are expensive and are not scalable with respect to clock rate, power consumption, and circuit area. This paper studies the characteristics of real-life Snort NIDS rule sets, and proposes a novel SRAM-based architecture. The proposed architecture is called field-split parallel bit vector (FSBV) where some header fields of a packet are further split into bit-level subfields. Unlike previous multi-match packet classification algorithms which suffer from memory explosion, the memory requirement of FSBV is linear in the number of rules. FPGA technology is exploited to provide high throughput and to support dynamic updates. Implementation results show that our architecture can store on a single Xilinx Virtex-5 FPGA the full set of packet header rules extracted from the latest Snort NIDS and sustains 100 Gbps throughput for minimum size (40 bytes) packets. The design achieves 1.25× improvement in throughput while the power consumption is approximately one fourth that of the state-of-the-art solutions.
A recent survey of self-embedding fragile watermarking scheme for image authentication with recovery capability (2019)

The rapid developments of storage technology and information exchange encourage the development of research in the field of information security. In the process of sending information, tamper and issues about data ownership may occur. The fragile watermarking is one technique that can overcome the problem, in which this technique exploits sensitivity to tamper with the inserted watermark components. Therefore, it is not tolerable to change even only one bit. Self-embedding can be defined as some important features obtained from a selected image as a watermark by modifying the pixel value of the original image. Once a picture which has been inserted with a watermark is modified by other users, it can be used for tamper detection and recovery images. Due to the importance of this fragile watermarking scheme, this paper discusses the principles and characteristics of a fragile watermarking algorithm. The main contribution of this paper survey is that it summarises the current mechanisms of selection, generation, method of watermark insertion, detection and tamper localisation and recovery procedures. Comparison of several watermarking techniques was analysed and presented in tabular form, as well as experimental evaluation of four watermarking schemes in many graphs to show the performance of the self-embedding fragile watermarking scheme.
Three-Dimensional Flow Perfusion Culture System for Stem Cell Proliferation Inside the Critical-Size β-Tricalcium Phosphate Scaffold (2006)

A 3-dimensional flow perfusion system has been created in our laboratory to provide continuous and homogeneous nutrient supply inside the critical-size beta-tricalcium phosphate (beta-TCP) scaffold and permit cell proliferation during long-term incubation. The critical-size porous cylindrical scaffold (14 mm in diameter, 30 mm in length) with a central tunnel was impregnated with sheep mesenchymal stem cells. In the flow perfusion group, the hybrid scaffolds were continuously perfused with complete alpha-minimum essential medium via a peristaltic pump for 7, 14, and 28 days. In the static culture group, the hybrid composites were immersed in the medium without perfusion for 14 and 28 days. The daily glucose consumption was much higher in the flow perfusion group than in the static group (p < 0.001). In the flow perfusion group, glucose consumption increased dramatically in the first 14 days, and the increase slowed in the last 14 days. In the static group, the increase occurred only in the first 14 days. Cell viability via MTT colorimetry increased with time, which coincided with the results of glucose consumption. Histological study showed that the cells proliferated through the whole scaffolds under the flow perfusion culture. While under the static culture, the cells survived and proliferated only inside the first to third rows of the macropores under the scaffold surface. The cell quantity increased with time under flow perfusion culture. The results suggest that flow perfusion culture is superior to static culture for mesenchymal stem cell proliferation in the critical-size porous scaffold. This perfusion culture system permits a constant nutrition supply into the center of a large-scale scaffold for at least 4 weeks. Determination of D-glucose in the culture medium is a noninvasive way to survey cell proliferation in this system.
Quantifying and interpreting collective behavior in financial markets (2001)

Firms having similar business activities are correlated. We analyze two different cross-correlation matrices C constructed from (i) 30-min price fluctuations of 1000 US stocks for the two-year period 1994-95 and (ii) one-day price fluctuations of 422 US stocks for the 35-year period 1962-96. We find that the eigenvectors of C corresponding to the largest eigenvalues allow us to partition the set of all stocks into distinct subsets. These subsets are similar to business sectors, and are stable for extended periods of time. We find that price fluctuations of these subsets are characterized by power-law decaying time correlations, reminiscent of strongly interacting systems.
Unexpected Preference of the <i>E. coli</i> Translation System for the Ester Bond during Incorporation of Backbone-Elongated Substrates (2007)

There have been recent advances in the ribosomal synthesis of various molecules composed of nonnatural ribosomal substrates. However, the ribosome has strict limitations on substrates with elongated backbones. Here, we show an unexpected loophole in the E. coli translation system, based on a remarkable disparity in its selectivity for beta-amino/hydroxy acids. We challenged beta-hydroxypropionic acid (beta-HPA), which is less nucleophilic than beta-amino acids but free from protonation, to produce a new repertoire of ribosome-compatible but main-chain-elongated substrates. PAGE analysis and mass-coupled S-tag assays of amber suppression experiments using yeast suppressor tRNAPheCUA confirmed the actual incorporation of beta-HPA into proteins/oligopeptides. We investigated the side-chain effects of beta-HPA and found that the side chain at position alpha and R stereochemistry of the beta-substrate is preferred and even notably enhances the efficiency of incorporation as compared to the parent substrate. These results indicate that the E. coli translation machinery can utilize main-chain-elongated substrates if the pKa of the substrate is appropriately chosen.
Miniaturized Cavity Ring-Down Detection in a Liquid Flow Cell (2005)

A novel method for applying cavity ring-down spectroscopy in the liquid phase, compatible with LC analyses, is presented. The core of the setup is a home-built cavity ring-down flow cell (cell volume 12 microL) that is constructed using a silicon rubber spacer, which is clamped leak-tight between two high-reflectivity mirrors. The mirrors are in direct contact with the liquid flow, which provides for a small path length and short ring-down times. Inside the cavity there are no windows, reflection losses, or Brewster angles to be considered. Due to the small size of the presented cavity geometry, the setup can be implemented in conventional-size LC apparatuses. With a flow injection setup, a detection limit of 2.5 nM was obtained for Crystal Violet in ethanol, and the linear dynamic range of the system is at least 2 orders of magnitude. The method has the potential to become a powerful alternative for commercial LC UV/visible absorbance detectors.
Contrast Enhanced Spiral Computerized Tomography in Live Kidney Donors:: A Single Session for Anatomical and Functional Assessment (2004)

Multidetector row spiral CT with contrast medium can provide accurate information regarding the anatomy of the urinary tract and vasculature of the kidney. Moreover, it can detect renal and vascular abnormalities that might be potentially significant for safe renal donation. In addition, it can accurately demonstrate selective GFR of each kidney. Therefore, we recommend spiral CT with contrast material as a single radiological diagnostic modality for the assessment of potential live kidney donors.
Frequent Pattern Mining in Web Log Data (2006)

Abstract: Frequent pattern mining is a heavily researched area in the field of data mining with wide range of applications. One of them is to use frequent pattern discovery methods in Web log data. Discovering hidden information from Web log data is called Web usage mining. The aim of discovering frequent patterns in Web log data is to obtain information about the navigational behavior of the users. This can be used for advertising purposes, for creating dynamic user profiles etc. In this paper three pattern mining approaches are investigated from the Web usage mining point of view. The different patterns in Web log mining are page sets, page sequences and page graphs.
Reliable Routings in Networks With Generalized Link Failure Events (2008)

We study routing problems in networks that require guaranteed reliability against multiple correlated link failures. We consider two different routing objectives: The first ensures ldquolocal reliability,rdquo i.e., the goal is to route so that each connection in the network is as reliable as possible. The second ensures ldquoglobal reliability,rdquo i.e., the goal is to route so that as few as possible connections are affected by any possible failure. We exhibit a trade-off between the two objectives and resolve their complexity and approximability for several classes of networks. Furthermore, we propose approximation algorithms and heuristics. We perform experiments to evaluate the heuristics against optimal solutions that are obtained using an integer linear programming solver. We also investigate up to what degree the routing trade-offs occur in randomly generated instances.
Konrad Koerner, ed. Edward Sapir: Appraisals of his Life and Work. Amsterdam Series in the Theory and History of Linguistic Science III. Studies in the History of the Language Sciences 36. Amsterdam: John Benjamins. 1984. (1986)

Konrad Koerner, ed. Edward Sapir: Appraisals of his Life and Work. Amsterdam Series in the Theory and History of Linguistic Science III. Studies in the History of the Language Sciences 36. Amsterdam: John Benjamins. 1984. - Volume 31 Issue 4
Front-line paclitaxel and irinotecan combination chemotherapy in advanced non-small-cell lung cancer: a phase I–II trial (2005)

Our purpose was to determine the efficacy of irinotecan plus paclitaxel administered on day 1, repeated every 2 weeks, in untreated patients with advanced or metastatic non-small-cell lung cancer (NSCLC). In total, 56 patients with inoperable or metastatic stage III and IV NSCLC with a histologically or cytologically confirmed diagnosis were enrolled. None of the patients had undergone prior chemotherapy or radiation therapy. Treatment involved irinotecan 125 mg m(-2) and paclitaxel 135 mg m(-2) administered on day 1 and repeated every 2 weeks for a planned number of nine cycles. With a standard dose of paclitaxel at 135 mg m(-2), the dosage of irinotecan was escalated at four levels: 75, 100, 125 and 150 mg m(-2); 125 mg m(-2) was established as the maximum tolerated dose; this dosage was administered to 46 patients. A total of 52 patients (median age 65 years, range 38-77 years) were assessable for toxicity and survival and 46 for response rate. Out of 46 evaluable patients, 19 achieved partial response (41.3%), 17 had stable disease (37%) and 10 (21.7%) experienced disease progression. The median duration of response was 6 months (range 2-9+ months). The main adverse reactions were myelotoxicity (grades 3 and 4) in 10 (19.2%) patients and diarrhoea (grade 3) in four (7.7%) patients. Irinotecan combined with paclitaxel, administered every 2 weeks, appears to be an effective treatment for advanced-stage NSCLC.
Commercial Methods of Analysis (1965)

Journal Article Commercial Methods of Analysis Get access Commercial Methods of Analysis. Foster Dee Snell and Frank M. Biffen. Revised edition, Chemical Publishing Company, Inc., New York, 1964. 753 pp. Price $12.00. William Hokwitz William Hokwitz Search for other works by this author on: Oxford Academic Google Scholar Journal of Association of Official Agricultural Chemists, Volume 48, Issue 4, 1 August 1965, Pages 869–870, https://doi.org/10.1093/jaoac/48.4.869a Published: 01 February 2020