gebhart/patrepeval huggingface dataset:
Cone-specific measures of human color vision. (1996)

Cone-specific contrast sensitivity provides a quantitative measure of normal color vision and indicates both type and severity of color deficiency. It is useful for diagnosing hereditary color deficiency and for monitoring early color vision loss in ocular and systemic disease.
Core IS Capabilities for Exploiting Information Technology (1998)

To achieve lasting competitiveness through IT, according to the authors, companies face three enduring challenges: focusing IS efforts to support business strategies and using IT innovations to develop new, superior strategies; devising and managing effective strategies for the delivery of low-cost, high-quality IS services; and choosing the technical platform on which to mount IS services. Three strands of research ? on the CIO's role and experience, the CIO's capabilities, and IS/IT outsourcing ? demonstrate that businesses need nine core IS capabilities to address these challenges: 

1. Leadership. Integrating IS/IT effort with business purpose and activity.

2. Business systems thinking. Envisioning the business process that technology makes possible.

3. Relationship building. Getting the business constructively engaged in IS/IT issues.

4. Architecture planning. Creating the blueprint for a technical platform that responds to current and future business needs.

5. Making technology work. Rapidly achieving technical progress ? by one means or another.

6. Informed buying. Managing the IS/IT sourcing strategy that meets the interests of the business.

7. Contract facilitation. Ensuring the success of existing contracts for IS/IT services.

8. Contract monitoring. Protecting the business's contractual position, current and future.

9. Vendor development. Identifying the potential added value of IS/IT service suppliers.

IS professionals and managers need to demonstrate a changing mix of technical, business, and interpersonal skills. The authors trace the role these skills play in achieving the core IS capabilities and discuss the challenges of adapting core IS capabilities to particular organizational contexts. Their core IS capability model implies migration to a relatively small IS function, staffed by highly able people. To sustain their ability to exploit IT, the authors conclude, organizations must make the design of flexible IS arrangements a high-priority task and take an anticipatory rather than a reactive approach to that task.
A Nanofibrillar Surface Promotes Superior Growth Characteristics in Cultured Human Retinal Pigment Epithelium (2011)

Surface topography appears to induce distinct RPE proliferation characteristics.
Simulation of the stretch blow molding process of PET bottles (1998)

Simulations of various stretch blow and blow moldings of axisymmetric PET bottles has been carried out using ABAQUS. A creep constitutive model with material data developed for a thermoforming process was used in the finite element analysis. Simulations using shell and solid elements were compared with experimental moldings. The creep material model, when combined with solid elements and a very high coefficient of friction, provided the best predictions for bottle side wall thickness, strains, blowing pressure, and general material movement. It was found that, using ABAQUS, the predicted wall thickness distribution of the material in an injection blow molded bottle agreed well with the values obtained using commercial process conditions. © 1998 John Wiley & Sons, Inc. Adv Polym Techn 17: 339–352, 1998
Protocol proposal for, and evaluation of, consistency in nicotine delivery from the liquid to the aerosol of electronic cigarettes atomizers: regulatory implications (2016)

Electronic cigarettes that use tank-type atomizers appear to deliver nicotine in more consistent quantities (within the acceptable limits for medicinal nebulizers and similar to the nicotine inhaler) than electronic cigarettes that use cartomizers. The protocol for testing nicotine delivery consistency described in this paper could be used effectively for regulatory purposes.
All-silica single-mode optical fiber with photonic crystal cladding: errata (1997)

See original paper at: \n&lt;A HREF="http://eprints.soton.ac.uk/78031/"&gt;http://eprints.soton.ac.uk/78031/&lt;/A&gt;
A Novel Real-Time Multiplex Reverse Transcriptase-Polymerase Chain Reaction for the Detection of HIV-1 RNA by Using Dual-Specific Armored RNA as Internal Control (2008)

DSPrtRT-PCR is a more efficient and effective viral assay with high sensitivity and specificity as compared to monospecificity probe PCR. It can be widely applied in blood donor screening and qualitative individual detection of HIV-1 RNA.
Prevention of Prion Propagation by Dehydrocholesterol Reductase Inhibitors in Cultured Cells and a Therapeutic Trial in Mice (2007)

In prion diseases, the normal cellular form of prion protein (PrP(C)) is converted into the disease-associated isoforms (PrP(Sc)) which accumulate in the infected tissues. Although the precise mechanism of this conversion remains unsolved, drugs of various categories have been reported to reduce the accumulation of PrP(Sc) in prion-infected cultured cells. We here show that AY-9944 (a 7-dehydrocholesterol reductase inhibitor) and U18666A (a 24-dehydrocholesterol reductase inhibitor) prevent PrP(Sc) from accumulating in prion-infected mouse neuroblastoma cells (ScN2a), with an ED50 of about 0.5 microM and 10 nM, respectively. In order to evaluate the efficacy of these two inhibitors in vivo, C57BL/6J mice inoculated with mouse-adapted scrapie-prion received repetitive intraperitoneal injections of U18666A (10 mg/kg) or a mixture of U18666A (10 mg/kg) and AY-9944 (12 mg/kg). By contrast to the potent anti-prion effects observed in ScN2a cells, the in vivo trial was abortive with neither drug halting the progression of the disease.
Superframe-based bit allocation algorithms for DMT systems (2002)

A superframe-based DMT transceiver system with multiple bit tables (SM-DMT) is proposed. This proposed system can be applied to either a frequency division multiplexed (FDM) DMT system or a time division multiplexed (TDM) DMT system. The latter system is also known as synchronized DMT (SDMT) systems. This paper shows how an SM-DMT system provides optimal performance in situations where either a FDM-based DMT system or a TDM-based DMT system may suffer from performance degradation. A bit allocation algorithm for SM-DMT systems is also presented. Simplified algorithms based on grouping and table-sharing are described to reduce the practical complexity requirement.
A Rule-Based Trust Negotiation System (2010)

Open distributed environments, such as the World Wide Web, facilitate information sharing but provide limited support to the protection of sensitive information and resources. Trust negotiation (TN) frameworks have been proposed as a better solution for open environments, in which parties may get in touch and interact without being previously known to each other. In this paper, we illustrate Protune, a rule-based TN system. By describing Protune, we will illustrate the advantages that arise from an advanced rule-based approach in terms of deployment efforts, user friendliness, communication efficiency, and interoperability. The generality and technological feasibility of Protune's approach are assessed through an extensive analysis and experimental evaluations.
Progress in overexpanded supersonic jets and skimmed molecular beams in free-jet zones of silence (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProgress in overexpanded supersonic jets and skimmed molecular beams in free-jet zones of silenceR. CampargueCite this: J. Phys. Chem. 1984, 88, 20, 4466–4474Publication Date (Print):September 1, 1984Publication History Published online1 May 2002Published inissue 1 September 1984https://pubs.acs.org/doi/10.1021/j150664a004https://doi.org/10.1021/j150664a004research-articleACS PublicationsRequest reuse permissionsArticle Views2438Altmetric-Citations228LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Synthesis and characterization of silver/alanine nanocomposites for radiation detection in medical applications: the influence of particle size on the detection properties (2012)

Silver/alanine nanocomposites with varying mass percentage of silver have been produced. The size of the silver nanoparticles seems to drive the formation of the nanocomposite, yielding a homogeneous dispersion of the silver nanoparticles in the alanine matrix or flocs of silver nanoparticles segregated from the alanine crystals. The alanine crystalline orientation is modified according to the particle size of the silver nanoparticles. Concerning a mass percentage of silver below 0.1%, the nanocomposites are homogeneous, and there is no particle aggregation. As the mass percentage of silver is increased, the system becomes unstable, and there is particle flocculation with subsequent segregation of the alanine crystals. The nanocomposites have been analyzed by transmission electron microscopy (TEM), UV-Vis absorption spectroscopy, X-ray diffraction (XRD), and Fourier transform infrared (FTIR) spectroscopy and they have been tested as radiation detectors by means of electron spin resonance (ESR) spectroscopy in order to detect the paramagnetic centers created by the radiation. In fact, the sensitivity of the radiation detectors is optimized in the case of systems containing small particles (30 nm) that are well dispersed in the alanine matrix. As the agglomeration increases, particle growth (up to 1.5 μm) and segregation diminish the sensitivity. In conclusion, nanostructured materials can be used for optimization of alanine sensitivity, by taking into account the influence of the particles size of the silver nanoparticles on the detection properties of the alanine radiation detectors, thus contributing to the construction of small-sized detectors.
Wideband receiver for Digital Radio Mondiale (2002)

Broadcasting within the traditional AM bands is set to change with the introduction of digital broadcasts. Wideband receiver architectures allow many of the advanced functions of standards such as Digital Radio Mondiale to be implemented and upgraded without changing the hardware. This article describes some of the design issues of wideband receivers and the performance of a practical receiver.
An 800-MHz monolithic GaAs HBT serrodyne modulator (1995)

An 800-MHz monolithic mixed-signal serrodyne modulator IC has been developed in a GaAs/AlGaAs HBT HI/sub 2/L process optimized for digital applications. This 3/spl times/2.8 mm, 2000+ transistor chip consists of a 7-b phase accumulator driving a vector modulator, implemented as a pair of balanced mixers, 5-b switched attenuators, buffer amplifiers, and central circuits. The balanced mixer's LO leakage and 3-1 products are typically 25 dB below the carrier at the nominal operating point, with all other products better than -50 dBc. Over a 32-dB control range, the 5-b switched attenuator typically achieves worst-case amplitude and phase errors of 1.5 dB and 1.5/spl deg/, respectively, from 50-250 MHz. DC-level variations versus attenuator-state limit the spurious response of an 800-MHz Composite DDS based on this serrodyne modulator to -20 dBc. Post-fabrication modeling indicates that a 5/spl deg/C thermal gradient across the IC may be responsible for this undesired dc-level variation. This first generation chip consumes 2.5 W of dc power and clocks to speeds in excess of 925 MHz.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Purification and characterization of N-acetyl-alpha-D-galactosaminidase from Gallus domesticus. (1992)

Exoglycosidases modify carbohydrate epitopes on glycoproteins and glycolipids. The N-acetyl-alpha-D-galactosaminidase from the domestic chicken, Gallus domesticus, is an important exoglycosidase which degrades the human blood group A epitope. This enzyme has never been demonstrably purified or thoroughly characterized. We have developed a technique to purify this enzyme to homogeneity. The isolated enzyme has a molecular weight of 49.1 kDa by SDS PAGE and 145.0 kDa by gel filtration. The enzyme is highly selective for PNP-N-acetyl-alpha-D-galactosaminide and is inactive against other low molecular weight substrates. The enzyme hydrolyzes the terminal N-acetyl-alpha-D-galactosaminide residues from blood group A2 erythrocytes. Protease activity is below detectable limits. The enzyme has a pH optima of 3.7, a pI of 8.15, is relatively unaffected by ionic strength, and is stable at 4 degrees C.
Improvement of TERCOM aided inertial navigation system by velocity correction (2012)

TERCOM is a terrain referenced navigation system using batch processing method which determines vehicle's current position by comparing a series of terrain height measurements with database. Generally, it is known that TERCOM operates well over terrain with high roughness. However, if the attitude and velocity error of INS is not corrected, the navigation solution of conventional TERCOM aided INS can diverge. This paper describes the TERCOM aided INS algorithm and show the divergence problem. To solve the problem, we propose an improved TERCOM aided INS algorithm which corrects the velocity error of INS using linear Kalman filter, even though the navigation system does not have a speedometer. It is shown that the proposed TERCOM algorithm can prevent divergence of navigation solution based on computer simulations.
Functional annotations improve the predictive score of human disease-related mutations in proteins (2009)

Single nucleotide polymorphisms (SNPs) are the simplest and most frequent form of human DNA variation, also valuable as genetic markers of disease susceptibility. The most investigated SNPs are missense mutations resulting in residue substitutions in the protein. Here we propose SNPs&GO, an accurate method that, starting from a protein sequence, can predict whether a mutation is disease related or not by exploiting the protein functional annotation. The scoring efficiency of SNPs&GO is as high as 82%, with a Matthews correlation coefficient equal to 0.63 over a wide set of annotated nonsynonymous mutations in proteins, including 16,330 disease-related and 17,432 neutral polymorphisms. SNPs&GO collects in unique framework information derived from protein sequence, evolutionary information, and function as encoded in the Gene Ontology terms, and outperforms other available predictive methods.
Directed Interesterification in Glycerides. III. The Synthesis of Single-Fatty Acid 1,3-Diglycerides<sup>1</sup> (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDirected Interesterification in Glycerides. III. The Synthesis of Single-Fatty Acid 1,3-Diglycerides1Fred J. Baur and Willy LangeCite this: J. Am. Chem. Soc. 1951, 73, 8, 3926–3928Publication Date (Print):August 1, 1951Publication History Published online1 May 2002Published inissue 1 August 1951https://pubs.acs.org/doi/10.1021/ja01152a109https://doi.org/10.1021/ja01152a109research-articleACS PublicationsRequest reuse permissionsArticle Views137Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Hydrocarbon class fractionation with bonded-phase liquid chromatography (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrocarbon class fractionation with bonded-phase liquid chromatographyRonald. MillerCite this: Anal. Chem. 1982, 54, 11, 1742–1746Publication Date (Print):September 1, 1982Publication History Published online1 May 2002Published inissue 1 September 1982https://doi.org/10.1021/ac00248a021RIGHTS & PERMISSIONSArticle Views145Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (596 KB) Get e-Alerts Get e-Alerts
Enhanced electrohydrodynamic force generation in a two-stroke cycle dielectric-barrier-discharge plasma actuator (2017)

An approach for electrohydrodynamic (EHD) force production is proposed with a focus on a charge cycle on a dielectric surface. The cycle, consisting of positive-charging and neutralizing strokes, is completely different from the conventional methodology, which involves a negative-charging stroke, in that the dielectric surface charge is constantly positive. The two-stroke charge cycle is realized by applying a DC voltage combined with repetitive pulses. Simulation results indicate that the negative pulse eliminates the surface charge accumulated during constant voltage phase, resulting in repetitive EHD force generation. The time-averaged EHD force increases almost linearly with increasing repetitive pulse frequency and becomes one order of magnitude larger than that driven by the sinusoidal voltage, which has the same peak-to-peak voltage.
Identification of Psychoactive Degradants of Cannabidiol in Simulated Gastric and Physiological Fluid (2016)

<b><i>Introduction:</i></b> In recent research, orally administered cannabidiol (CBD) showed a relatively high incidence of somnolence in a pediatric population. Previous work has suggested that when CBD is exposed to an acidic environment, it degrades to Δ<sup>9</sup>-tetrahydrocannabinol (THC) and other psychoactive cannabinoids. To gain a better understanding of quantitative exposure, we completed an <i>in vitro</i> study by evaluating the formation of psychoactive cannabinoids when CBD is exposed to simulated gastric fluid (SGF). <b><i>Methods:</i></b> Materials included synthetic CBD, Δ<sup>8</sup>-THC, and Δ<sup>9</sup>-THC. Linearity was demonstrated for each component over the concentration range used in this study. CBD was spiked into media containing 1% sodium dodecyl sulfate (SDS). Samples were analyzed using chromatography with UV and mass spectrometry detection. An assessment time of 3 h was chosen as representative of the maximal duration of exposure to gastric fluid. <b><i>Results:</i></b> CBD in SGF with 1% SDS was degraded about 85% after 60 min and more than 98% at 120 min. The degradation followed first-order kinetics at a rate constant of -0.031 min<sup>-1</sup> (<i>R</i><sup>2</sup>=0.9933). The major products formed were Δ<sup>9</sup>-THC and Δ<sup>8</sup>-THC with less significant levels of other related cannabinoids. CBD in physiological buffer performed as a control did not convert to THC. Confirmation of THC formation was demonstrated by comparison of mass spectral analysis, mass identification, and retention time of Δ<sup>9</sup>-THC and Δ<sup>8</sup>-THC in the SGF samples against authentic reference standards. <b><i>Conclusions:</i></b> SGF converts CBD into the psychoactive components Δ<sup>9</sup>-THC and Δ<sup>8</sup>-THC. The first-order kinetics observed in this study allowed estimated levels to be calculated and indicated that the acidic environment during normal gastrointestinal transit can expose orally CBD-treated patients to levels of THC and other psychoactive cannabinoids that may exceed the threshold for a physiological response. Delivery methods that decrease the potential for formation of psychoactive cannabinoids should be explored.
Mining software engineering data (2010)

Software engineering data (such as code bases, execution traces, historical code changes, mailing lists, and bug databases) contains a wealth of information about a project's status, progress, and evolution. Using well-established data mining techniques, practitioners and researchers have started exploring the potential of this valuable data in order to better manage their projects and to produce higher quality software systems that are delivered on time and within budget.
Evaluation of ovarian cancer biomarkers HE4 and CA-125 in women presenting with a suspicious cystic ovarian mass (2011)

In our study, population HE4 did not outperform CA-125. Based on our data a prospective trial with patients already diagnosed with an ovarian cyst may be conducted.