gebhart/patrepeval huggingface dataset:
An eigenvector method for shape-from-shading (2004)

We explore how spectral methods for graph seriation can be used to develop a new shape-from-shading algorithm. We characterise the field of surface normals using a transition matrix whose elements are computed from the sectional curvature between different image locations. We use a graph seriation method to define a curvature minimising surface integration path for the purposes of height reconstruction. To smooth the reconstructed surface, we fit quadric patches to the height data. The smoothed surface normal directions are updated ensuring compliance with Lambert's law. The processes of height recovery and surface normal adjustment are interleaved and iterated until a stable surface is obtained. We provide results on synthetic and real-world imagery.
Co-constructed narratives in online, collaborative mathematics problem solving (2005)

Our approach to the study of the narrative aspects of learning mathematical problem-solving extends the conception of narrative as the central artefact of interest, to include the process of collaborative dialog and emergent narratives. This perspective favours the conception of the dialogical aspects of interaction as shared achievements of co-participants and central meaning-making procedures. On the other hand, our qualitative analysis of transcripts of collaborative problem-solving interactions online revealed striking resemblances with the narrative form. Based on these observations we attempt to establish a link between the narrative and dialogical perspectives and explore relevant implications for the design of the Virtual Math Teams collaborative learning environment. Truth is not to be found inside the head of an individual person, it is born between people collectively searching for truth, in the process of their dialogic interaction. (Bakhtin, [1], p.110) Introduction Research in the field of Narrative Learning Environments (NLEs) is concerned with questions such as how to characterize the contribution of narratives and narration to learning, and how to use knowledge of narratives to design learning environments. As part of the Virtual Math Teams (VMT, see http://mathforum.org/wiki/VMT) research project, we have investigated talk-in interaction within the context of collaborative mathematical problemsolving online and have found similarities and differences between the narrative approach and a dialogical perspective on sense-making and interaction. Therefore, we propose to extend the idea narrative learning environments to encompass collaborative discourse-construction environments which, in addition to using narratives, offer also the possibility of collaboratively building meaning-centered narratives integrating a diverse set of linguistic and extra-linguistic objects (e.g. mathematical objects and their derivative properties). In the following sections we present these perspectives and offer some reflections for future research and development. The next section briefly presents the problematic of narrative learning environments. Section 2 introduces the main ideas of the dialogical theory of Mikhail Mikhailovici Bakhtin and its relevance for narrative learning. Section 3 presents in detail a qualitative analysis of a chat transcript as part of the VMT project. Section 4 concludes with some implications for design and future research.
The Role of Liver Transplantation in Hepatobiliary Malignancy. A Retrospective Analysis of 95 Patients with Particular Regard to Tumor Stage and Recurrence (1989)

The role of hepatic transplantation in patients with nonresectable liver or bile duct cancer remains a controversial issue. An analysis of 95 consecutive cases was undertaken to evaluate retrospectively the pathological tumor stage--in accordance with the TNM system--and outcome after transplantation. Included were patients with the following diagnoses: hepatocellular carcinoma (n = 52), cholangiocellular carcinoma (n = 10), hepatoblastoma (n = 2), hemangiosarcoma (n = 2), bile duct carcinoma (n = 20), and liver metastases from different primary tumors (n = 9). The overall actuarial survival rate at 5 years was 20.4%. Median survival improved significantly within the last 4 years as compared to the preceding era (18.06 vs. 4.0 months). Currently 27 patients are alive, with the longest follow-up more than 12 years. The incidences of residual or recurrent tumor were 27 and 28, respectively. Particularly in patients who underwent transplantation for hepatocellular or bile duct carcinoma without extra-hepatic tumor spread, the results were significantly better; median survival time achieved for these two groups were 120 (p less than 0.01) and 35 months (p less than 0.05). Prolonged survival without tumor recurrence was not seen in patients with cholangiocellular carcinoma or liver metastases. These results demonstrate clearly that liver transplantation for hepatobiliary malignancy is still justified on the premises of careful patient selection by adequate tumor staging.
Anionic<i>N</i>-Fries Rearrangement of<i>N</i>-Carbamoyl Diarylamines to Anthranilamides. Methodology and Application to Acridone and Pyranoacridone Alkaloids (2006)

[reaction: see text] A general alkyllithium/LDA-mediated rearrangement of N-carbamoyl diarylamines 7a-g into the anthranilamides 8a-g and 9a-g (Table 1) is presented and applied to a regioselective efficient construction of acridone (17) and pyranoacridone (18) alkaloids (Scheme 4).
Determination of Volatile Organic Compounds at the Parts per Trillion Level in Complex Aqueous Matrixes Using Membrane Introduction Mass Spectrometry (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Volatile Organic Compounds at the Parts per Trillion Level in Complex Aqueous Matrixes Using Membrane Introduction Mass SpectrometryScott. Bauer and David. SolyomCite this: Anal. Chem. 1994, 66, 24, 4422–4431Publication Date (Print):December 15, 1994Publication History Published online1 May 2002Published inissue 15 December 1994https://pubs.acs.org/doi/10.1021/ac00096a006https://doi.org/10.1021/ac00096a006research-articleACS PublicationsRequest reuse permissionsArticle Views264Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Generation and detection of terahertz pulsed radiation with photoconductive antennas and its application to imaging (2002)

We describe the basic properties of photoconductive (PC) antennas as emitters and detectors of terahertz (THz) pulsed radiation. The efficiency of PC antennas is discussed, taking into account the saturation effect due to field screening by photo-generated carriers. We show that maximum emission efficiency under a constant pump power condition is achieved by adjusting the PC gap size so that the pump intensity (power divided by PC area) is equal to the characteristic saturation intensity. We also discuss the bandwidth of PC antennas and conclude that PC antennas are capable of generating and detecting ultra-broad THz radiation beyond 10 THz when short enough laser pulses are used. Our conclusion is demonstrated experimentally by detecting ultra-broadband THz radiation, whose spectrum distributed up to 40 THz, with a PC antenna. As an example of applications of THz pulsed radiation based on a PC emitter-detector system, results for the imaging of objects in powders are presented and discussed.
Titanium and Zirconium Complexes of Dianionic and Trianionic Amine−Phenolate-Type Ligands in Catalysis of Lactide Polymerization (2006)

The synthesis of alkoxotitanium(IV) and -zirconium(IV) complexes of seven chelating tetradentate di- or trianionic amine-phenolate ligands belonging to three families and their application in L-lactide polymerization are described. The isopropoxotitanium complexes were synthesized by a direct reaction between the ligand precursors and titanium tetraisopropoxide, whereas the zirconium complexes were synthesized by various routes. For titanium, complexes of all seven ligands could be synthesized. For zirconium, the hexacoordinate complexes derived from all dianionic ligands were synthesized; however, the only pentacoordinate complex that could be produced was the one derived from the bulky trianionic ligand. X-ray structures of zirconium complexes of the three families indicated a substantial pi donation from the alkoxo ligand to the metal. All complexes were found to be active lactide polymerization catalysts, and their activity was found to depend strongly on the metal, the coordination number around the metal, and the phenolate substituents but not on the ligand backbone.
Circadian variation in serum free and non‐SHBG‐bound testosterone in normal men: measurements, and simulation using a mass action model (1993)

Increasing saturation of the binding proteins following rises in testosterone production, and the small but significant changes in protein concentration, probably related to postural changes, were implicated as the major factors in the rhythm amplitude. However, the early morning decline in the non-SHBG-bound fraction was not explained by these factors. The rise in cortisol concentration at this time is a probable cause. Alternatively, simulation suggests that a substance appearing in the early morning and competing with testosterone for albumin binding sites may be responsible.
The Adaptor Molecule MyD88 Directly Promotes CD8 T Cell Responses to Vaccinia Virus (2009)

Vaccinia virus (VACV) elicits a robust CD8 T cell response that plays an important role in host resistance. To date, there is little information on the molecules that are essential to generate large pools of VACV-specific effector CD8 T cells. In this study, we show that the adaptor molecule MyD88 is critical for the magnitude of primary CD8 T cell responses to both dominant and subdominant VACV epitopes. MyD88(-/-) mice exhibit profound reduction in CD8 T cell expansion and antiviral cytokine production. Surprisingly, the defect was not due to impaired APC function, as MyD88(-/-) dendritic cells matured normally and were able to promote strong CD8 T cell priming following VACV infection. Rather, adoptive transfer experiments demonstrated that intrinsic MyD88-dependent pathways in CD8 T cells were critical. MyD88-deficient CD8 T cells failed to accumulate in wild-type hosts and poor expansion of MyD88-deficient VACV-specific CD8 T cells resulted after virus infection. In contrast, no defect was evident in the absence of TRIF, TLR2, TLR4, TLR9, and IL-1R. Together, our results highlight an important role for MyD88 in initial antiviral CD8 T cell responses and suggest that targeting this pathway may be useful in promoting and sustaining anti-VACV immunity.
Kidneys contribute to the extrahepatic clearance of propofol in humans, but not lungs and brain (2005)

We have demonstrated substantial renal extraction of propofol in human. Metabolic clearance of propofol by the kidneys accounts for almost one-third of total body clearance and may be the major contributor to the extrahepatic elimination of this drug.
HDTV single-chip CCD color camera (1990)

An HDTV (high-definition television) color camera has been developed by using a novel color-coding method, the field sequential color-coding method, to suppress spurious color signals. This camera has realized a high resolution of more than 850 TV lines without color moire and spurious color signals. Since the size and weight are 1/5 that of an HDTV 3-CCD color camera, it is suitable for both industrial and home use.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
High Efficiency High Step-up Isolated DC-DC Converter for Photovoltaic Applications (2019)

A high efficiency and high step-up isolated DC-DC converter with a new topology configuration for photovoltaic (PV) application is proposed in this paper. This converter consists of a Zero-Voltage-Switching (ZVS) and Zero-Current-Switching (ZCS) current-fed push-pull converter as a DC transformer dealing with most of power and an active clamp flyback (ACF) converter as a regulator with considerable high efficiency within a large conversion range. The two converters are constructed with the input-parallel-output-series (IPOS) structure. The input-parallel connection is able to share the large input current as well as reduce the current ripple, while the output-series connection is used to increase the output voltage gain. A 400 V / 400 W experimental prototype with an input voltage range of 24 V - 32 V is built. The maximum efficiency reaches at 95.1%. The experimental result validates the correctness of the analysis and proves the feasibility of the proposed topology for the photovoltaic applications.
Real-time collaborative design of complex objects on the Web (2003)

Real-time collaborative design of complex objects across great distances has been made much easier through the World Wide Web. A number of issues, however, need to be resolved. These include the sharing and exchange of information on the designed objects, the coordination and control of the collaborative design activities, and the management of the different design versions. This paper explores these three issues and describes a prototype system that resolves the issues in the context of the collaborative design of complex geometrical objects.
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases (2019)

The gold standard for a definitive diagnosis of Parkinson disease (PD) is the pathologic finding of aggregated α-synuclein into Lewy bodies and for Alzheimer disease (AD) aggregated amyloid into plaques and hyperphosphorylated tau into tangles. Implicit in this clinicopathologic-based nosology is the assumption that pathologic protein aggregation at autopsy reflects pathogenesis at disease onset. While these aggregates may in exceptional cases be on a causal pathway in humans (e.g., aggregated α-synuclein in <i>SNCA</i> gene multiplication or aggregated β-amyloid in <i>APP</i> mutations), their near universality at postmortem in sporadic PD and AD suggests they may alternatively represent common outcomes from upstream mechanisms or compensatory responses to cellular stress in order to delay cell death. These 3 conceptual frameworks of protein aggregation (pathogenic, epiphenomenon, protective) are difficult to resolve because of the inability to probe brain tissue in real time. Whereas animal models, in which neither PD nor AD occur in natural states, consistently support a pathogenic role of protein aggregation, indirect evidence from human studies does not. We hypothesize that (1) current biomarkers of protein aggregates may be relevant to common pathology but not to subgroup pathogenesis and (2) disease-modifying treatments targeting oligomers or fibrils might be futile or deleterious because these proteins are epiphenomena or protective in the human brain under molecular stress. Future precision medicine efforts for molecular targeting of neurodegenerative diseases may require analyses not anchored on current clinicopathologic criteria but instead on biological signals generated from large deeply phenotyped aging populations or from smaller but well-defined genetic-molecular cohorts.
Premature termination of telomeric extension-PCR for detection of telomerase activity (2003)

In this article, we report a simple, rapid, and efficient method to detect telomerase activity: the premature termination of telomeric extension-PCR (PTEP). Similar to the telomeric repeat amplification protocol (TRAP), this method is based on PCR amplification following the in vitro telomerase reaction, while the in vitro telomerase reaction here is prematurely, rather than randomly, terminated. Apart from this, the telomeric extension products are used as initial primers, instead of as templates, to trigger the amplification with a specially constructed plasmid DNA as the template that cannot be directly amplified with the telomerase primer. The end product is a specific 159-bp DNA fragment that reflects telomerase activity. Because its product can be clearly identified with routine agarose gel electrophoresis and ethidium bromide staining, PTEP allows even lesser-equipped laboratories to easily detect telomerase activity.
The Large-Scale Organization of the Centromeric Region in<i>Beta</i>Species (2001)

In higher eukaryotes, the DNA composition of centromeres displays a high degree of variation, even between chromosomes of a single species. However, the long-range organization of centromeric DNA apparently follows similar structural rules. In our study, a comparative analysis of the DNA at centromeric regions of Beta species, including cultivated and wild beets, was performed using a set of repetitive DNA sequences. Our results show that these regions in Beta genomes have a complex structure and consist of variable repetitive sequences, including satellite DNA, Ty3-gypsy-like retrotransposons, and microsatellites. Based on their molecular characterization and chromosomal distribution determined by fluorescent in situ hybridization (FISH), centromeric repeated DNA sequences were grouped into three classes. By high-resolution multicolor-FISH on pachytene chromosomes and extended DNA fibers we analyzed the long-range organization of centromeric DNA sequences, leading to a structural model of a centromeric region of the wild beet species Beta procumbens. The chromosomal mutants PRO1 and PAT2 contain a single wild beet minichromosome with centromere activity and provide, together with cloned centromeric DNA sequences, an experimental system toward the molecular isolation of individual plant centromeres. In particular, FISH to extended DNA fibers of the PRO1 minichromosome and pulsed-field gel electrophoresis of large restriction fragments enabled estimations of the array size, interspersion patterns, and higher order organization of these centromere-associated satellite families. Regarding the overall structure, Beta centromeric regions show similarities to their counterparts in the few animal and plant species in which centromeres have been analyzed in detail.
POLARISATION INSENSITIVE HETERODYNE DETECTION USING POLARISATION SCRAMBLING (1987)

Practical coherent optical fibre transmission systems will have to be insensitive to the random polarisation changes introduced by the birefringent transmission medium and to date the techniques considered for achieving this are polarisation tracking receivers [1] and polarisation diversity receivers [2]. In this paper an alternative technique is reported which achieves diversity by scrambling the polarisation at the transmitter subsequent to modulating the optical carrier. The advantages of this technique are that for wavelength multiplexed systems one scrambler per transmission fibre is all that is required and because the receiver design is kept simple it is particularly suited to local network applications.
An effective POS MPPT control method for PV power generation system (2009)

An effective POS (Photovoltaic Output Sensorless) MPPT (Maximum Power Point Tracking) control method for PV (PhotoVoltaic) power generation system is proposed in this paper. A fuzzy logic based algorithm, which has a simple feedback structure and fewer measured parameters, is proposed and applied to the control strategy of a DC/DC converter for effective realization of MPPT (Maximum Power Point Tracking). The main advantages of this method are that the oscillation of power around at maximum power point and tracking time can be minimized, and the cost of overall system can be reduced as well. The effectiveness of proposed method is demonstrated through the simulation and experiment of a model PV power generation system.
Sorting using BItonic netwoRk wIth CUDA (2009)

Novel “manycore” architectures, such as graphics processors, are high-parallel and high-performance shared-memory architectures [7] born to solve specific problems such as the graphical ones. Those architectures can be exploited to solve a wider range of problems by designing the related algorithm for such architectures. We present a fast sorting algorithm implementing an efficient bitonic sorting network. This algorithm is highly suitable for information retrieval applications. Sorting is a fundamental and universal problem in computer science. Even if sort has been extensively addressed by many research works, it still remains an interesting challenge to make it faster by exploiting novel technologies. In this light, this paper shows how to use graphics processors as coprocessors to speed up sorting while allowing CPU to perform other tasks. Our new algorithm exploits a memory-efficient data access pattern maintaining the minimum number of accesses to the memory out of the chip. We introduce an efficient instruction dispatch mechanism to improve the overall sorting performance. We also present a cache-based computational model for graphics processors. Experimental results highlight remarkable improvements over prior CPU-based sorting methods, and a significant improvement over previous GPU-based sorting algorithms.
Increased Yield of PCR Products by Addition of T4 Gene 32 Protein to the SMART™ PCR cDNA Synthesis System (2001)

Under certain conditions, T4 gene 32 protein is known to increase the efficiency of different enzymes, such as Taq DNA polymerase, reverse transcriptase, and telomerase. In this study, we compared the efficiency of the SMART PCR cDNA synthesis kit with and without the T4 gene 32 protein. The use of this cDNA synthesis procedure, in combination with T4 gene 32 protein, increases the yield of RT-PCR products from approximately 90% to 150%. This effect is even observed for long mRNA templates and low concentrations of total RNA (25 ng). Therefore, we suggest the addition of T4 gene 32 protein in the RT-PCR mixture to increase the efficiency of cDNA synthesis, particularly in cases when low amounts of tissue are used.