gebhart/patrepeval huggingface dataset:
The Phenyl- and Biphenyl-Quinolizidines of In-Vitro-Grown Heimia salicifolia (1985)

Under the conditions delineated in this paper, alkaloid synthesis was not detectable in heterotrophic callus and suspension cultures of Heimia salicifolia. However, in vitro-grown shoots are active in alkaloid biosynthesis, yielding the biphenylquinolizidine lactones vertine (1), lytrine (5), and lyfoline (7), the ester alkaloids demethoxyabresoline (14) and epidemethoxylabresoline (11), the phenylquinolizidinols demethyllasubine-I (10) and demethyllasubine-II (12), and several minor alkaloids that had not been previously shown to occur in H. salicifolia.
Peripheral blood stem cell transplantation followed by recombinant alpha interferon for chronic myelogenous leukemia in chronic phase: Preliminary results (1993)

Journal Article Peripheral blood stem cell transplantation followed by recombinant alpha interferon for chronic myelogenous leukemia in chronic phase: Preliminary results Get access J. Reiffers, J. Reiffers French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Correspondence: Professor J. Reiffers, Bone Marrow Transplant Unit, CHR Bordeaux, Hǒpital Haut-Levěque, 33604 Pessac, France Search for other works by this author on: Oxford Academic Google Scholar J. Y. Cahn, J. Y. Cahn French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar M. Montastruc, M. Montastruc French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar D. Caillot, D. Caillot French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar G. Souillet, G. Souillet French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar V. Leblond, V. Leblond French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar J. Troncy, J. Troncy French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar C. Faberes C. Faberes French Society for Bone Marrow Transplantation, Hǒpital Haut-Levěque, Pessac, France Search for other works by this author on: Oxford Academic Google Scholar Stem Cells, Volume 11, Issue S3, 1993, Pages 23–24, https://doi.org/10.1002/stem.5530110908 Published: 01 January 1996 Article history Received: 15 June 1993 Accepted: 15 June 1993 Published: 01 January 1996
Proposal of Seeking Wireless Station by Flight Drones Based on Delay Tolerant Networks (2014)

Although the information network has become more important for the daily life, there are some considerable subjects such as the poor connectivity in disasters, local areas, and developing areas. On the other hands, the rapid developments of Information Technology expect to bring new usages of technologies, and one of the expectations is autonomous flight drones with IP wireless networks. Therefore, in this paper, the Autonomous Flight Wireless Node (AFW) is introduced for the delivery of message data under the poor network conditions such as disasters or local areas. This paper especially discusses the data connections with the DTN (Delay Tolerant Networks) and autonomous flights for seeking possible encounters. Then, the implementations and the experimentations of the prototype system are carried out for the effectiveness of the functions. Finally, the results are used for the discussions of the future studies.
Influences ions, enzymes, and detergents on gamma-aminobutyric acid-receptor binding in synaptic membranes of rat brain. (1977)

<p>Spinor condensates have proven to be a rich area for probing many-body phenomena richer than that of an ultracold gas consisting of atoms restricted to a single spin state. In the strongly correlated regime, the physics controlling the possible novel phases of the condensate remains largely unexplored, and few-body aspects can play a central role in the properties and dynamics of the system through manifestations of Efimov physics. The present study solves the three-body problem for bosonic spinors using the hyperspherical adiabatic representation and characterizes the multiple families of Efimov states in spinor systems as well as their signatures in the scattering observables relevant for spinor condensates. These solutions exhibit a rich array of possible phenomena originating in universal few-body physics, which can strongly affect the spin dynamics and three-body mean-field contributions for spinor condensates. The collisional aspects of atom-dimer spinor condensates are also analyzed, and effects are predicted that derive from Efimov physics.</p>
A new technology for precise local position measurement -LPM (2004)

Precise measurement of the local position of moveable targets in three dimensions is still considered to be a challenge. With the presented local position measurement (LPM) technology a novel system, consisting of small and lightweight measurement transponders and a number of fixed base stations, is introduced. The new system is operating in the 5.8 GHz ISM-band and can handle up to 1000 measurements per second with accuracies down to few centimeters. Measurement results obtained with prototype boards demonstrate the feasibility of the proposed technology in practical applications. There exist a broad range of various applications, such as tracking of persons or controlling autonomous vehicles in industrial or logistic applications.
The Art and Science of Dermal Formulation Development (2019)

The Art and Science of Dermal Formulation Development is a comprehensive guide to the theory and practice of transdermal and topical formulation development, covering preclinical studies, evaluation, and regulatory approval. It enables the reader to understand the opportunities and challenges in developing products and how risks can be mitigated. Over the last 25 years, expertise in this area has declined whilst drug delivery systems for other administration routes have developed significantly. The advantages offered by transdermal and topical drug delivery remain compelling for sectors including the pharmaceutical industry, personal care, and cosmetics. This text addresses the dearth of expertise and discusses how skin can be a route of delivery and the processes in formulation development, but how such an application is very different to that used for oral, IV, and other administration routes. Key Features: Presents a practical guide for both industry and academia Focuses on and draws together the fundamental principles behind transdermal and topical drug delivery Illustrates the practicalities of formulation design using key case studies Gives an understanding of the skin as a route of delivery and how formulation development for such application differs from that for other administration routes
Applying Particle Swarm Optimization to Prioritizing Test Cases for Embedded Real Time Software Retesting (2008)

In recent years, complex embedded systems are used in every device that is infiltrating our daily lives. Since most of the embedded systems are multi-tasking real time systems, the task interleaving issues, dead lines and other factors needs software units retesting to follow the subsequence changes. Regression testing is used for the software maintenance that revalidates the old functionality of the software unit. Testing is one of the most complex and time-consuming activities, in which running of all combination of test cases in test suite may require a large amount of efforts. Test case prioritization techniques can take advantage that orders test cases, which attempts to increase effectiveness in regression testing. This paper proposes to use particle swarm optimization (PSO) algorithm to prioritize the test cases automatically based on the modified software units. Regarding to the recent investigations, PSO is a multi-object optimization technique that can find out the best positions of the objects. The goal is to prioritize the test cases to the new best order, based on modified software components, so that test cases, which have new higher priority, can be selected in the regression testing process. The empirical results show that by using the PSO algorithm, the test cases can be prioritized in the test suites with their new best positions effectively and efficiently.
Relative scheduling under timing constraints: algorithms for high-level synthesis of digital circuits (1992)

For the synthesis of ASIC design that interface with external signals and events, timing constraints and operations with unbounded delays, i.e. delays unknown at compile time, must be considered. The authors present a relative scheduling formulation that supports operations with fixed and unbounded delays. The start time of an operation is specified in terms of offsets from the set of unbounded delay operations called anchors. The authors analyze a property, called well-posedness, of timing constraints. It is used to identify consistency of constraints in the presence of unbounded delay operations. The authors present an algorithm that will transform an ill-posed constraint graph into a minimally serialized well-posed constraint graph, if one exists. The anchors are then checked for redundancy, and they identify the minimum set of anchors that are required in computing the start time. They present an algorithm that schedules the operations relative to the anchors and yields a minimum schedule that satisfies the timing constraints, or detects whether no schedule exists, in polynomial time. They describe the generation of control logic from the resulting relative schedule.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Design of a Novel Capacitorless DRAM Cell with Enhanced Retention Performance (2009)

A novel capacitorless DRAM cell with enhanced retention performance is investigated. The write / read mechanisms, speed, retention performance are studied with numerical simulations. Further, the manufacturing method of this device is briefly discussed.
Analysis of noise avoidance techniques in DSM interconnects using a complete crosstalk noise model (2003)

Noise estimation and avoidance are becoming critical, 'must have' capabilities in today's high performance IC design. An accurate yet efficient crosstalk noise model which contains as many driver/interconnect parameters as possible, is necessary for any sensitivity based noise avoidance approach. In this paper, we present a complete analytical crosstalk noise model which incorporates all physical properties including victim and aggressor drivers, distributed RC characteristics of interconnects and coupling locations in both victim and aggressor lines. We present closed-form analytical expressions for peak noise and noise width as well as sensitivities to all model parameters. We then use them model parameter sensitivities to analyze and evaluate various noise avoidance techniques such as driver sizing, wire sizing, wire spacing and layer assignment. Both our model and noise avoidance evaluations are verified using realistic circuits in 0.13/spl mu/ technology. We also present effectiveness of discussed noise avoidance techniques on a high performance microprocessor core.
Solid-Phase Library Synthesis of Bi-Functional Derivatives of Oleanolic and Maslinic Acids and Their Cytotoxicity on Three Cancer Cell Lines (2014)

A wide set of 264 compounds has been semisynthesized with high yields and purities. These compounds have been obtained through easy synthetic processes based on a solid-phase combinatorial methodology. All the members of this library have one central core of a natural pentacyclic triterpene (oleanolic or maslinic acid) and differ by 6 amino acids, coupled with the carboxyl group at C-28 of the triterpenoid skeleton, and by 10 different acyl groups attached to the hydroxyl groups of the A-ring of these molecules. According to the literature on the outstanding and promising pharmacological activities of other similar terpene derivatives, some of these compounds have been tested for their cytotoxic effects on the proliferation of three cancer cell lines: B16-F10, HT29, and Hep G2. In general, we have found that around 70% of the compounds tested show cytotoxicity in all three of the cell lines selected; around 60% of the cytotoxic compounds are more effective than their corresponding precursors, that is, oleanolic (OA) or maslinic (MA) acids; and nearly 50% of the cytotoxic derivatives have IC50 values between 2- to 320-fold lower than their corresponding precursor (OA or MA).
Prediction of smart antenna transmitter characteristics using a new behavioral modeling approach (2014)

A new technique for analysis of nonlinear effects in smart antenna array transmitter systems is presented. The analysis is founded on a new type of dual-input circuit behavioral model which allows nonlinear effects caused by antenna mutual-coupling and mismatch to be predicted under realistic wideband signal excitations. The model formulation enables direct interface with multi-port antenna S-parameters and detailed prediction of radiated field characteristics. The method is validated by over-the-air WCDMA measurements on a dual-antenna 2.14 GHz MIMO transmitter. The results demonstrate that antenna mutual coupling may lead to significant nonlinear distortion that cannot be compensated for by conventional linearization techniques.
Comparative Study of the Power and Cycling Performance for Advanced Lithium-Ion Capacitors with Various Carbon Anodes (2014)

In recent years, an increased attention has been focused on Li-ion capacitors (LICs) which are high power hybrid devices. Various carbon materials (hard carbon (HC), soft carbon (SC) and graphite) have been investigated for use as the negative electrodes for LICs. The rate capabilities are compared by half cells with carbon anode as working electrode and lithium foil as counter electrode, and by LIC full cells with test current density up to 20 mA cm−2. It is found that the LIC with HC and SC at 20 mA cm−2can be maintained up to 72.5% and 70%, compared to that at 0.5 mA cm−2, which is better power performance than the graphite materials. LICs with both HC and SC as anodes displayed better cycle lifes than graphite anode. After 100,000 high-rate charge-discharge cycles, the capacity retention of the LIC with HC anode maintained higher than 85%. The Scanning electron microscopy (SEM) images, surface area and the pore size distribution are also studied and compared for the various carbon anode materials.
Context-sensitive semantic query expansion (2003)

Modern information retrieval systems match the terms included in a user's query with available documents, through the use of an index. A fuzzy thesaurus is used to enrich the query with associated terms. In this work, we use semantic entities, rather than terms; this allows us to use knowledge stored in a semantic encyclopedia, specifically the ordering relations, in order to perform a semantic expansion of the query. The process of query expansion takes into account the query context, which is defined as a fuzzy set of semantic entities. Furthermore, we integrate our approach with the user's profile.
Behavior of metallic iron catalysts during Fischer-Tropsch synthesis studied with Mössbauer spectroscopy, x-ray diffraction, carbon content determination, and reaction kinetic measurements (1980)

The conversion of unpromoted, unsupported metallic iron catalysts into carbides during Fischer-Tropsch synthesis (CO:H2:He = 1:1:3, 1 atm) was studied with Mössbauer spectroscopy, X-ray diffraction, carbon content analysis, and reaction kinetic measurements. From a comparison between experiments at different temperatures and literature data, it is concluded that both reaction conditions and the nature of the iron catalyst determine the combination of carbides that will be formed. Investigation of single-phase carbides revealed that the X-ray diffraction pattern commonly ascribed to a pseudohexagonal carbide Fe2C actually belongs to the carbide ∈′-Fe2.2C. At synthesis temperatures of 513 K and lower, unknown iron-carbon species were found, referred to as FexC. It is believed that FexC represents poorly defined structures between α-Fe and a crystallographic carbide. The behavior of metallic iron catalysts during Fischer-Tropseh synthesis at 513 K was studied in more detail as a function of time. It was found that the rate of hydrocarbon formation was initially low, passed through a maximum, and decreased thereupon, while the conversion of α-Fe into carbides started at a high rate and decreased rapidly. These results can be understood as the consequence of either a competition between bulk carbidization and hydrocarbon synthesis or a relatively slow activation of α-Fe for the formation of hydrocarbons in which bulk carbidization plays no role. Deactivation is caused by the formation of an excessive amount of inactive carbon at the surface of the catalyst.
A review of research on equine locomotion and biomechanics (1983)

A review of the literature about equine locomotion and biomechanics is presented to summarise available knowledge and provide perspective to current and proposed research programmes. It is evident that much past research has failed to provide sufficient information on basic principles of these two disciplines and that information is now required before progress can be made on more applied research topics. However, useful contributions have been made in gait typology, analysis of racetrack surface and design and limb kinetics, kinematics and coordination.
“Nojirimycin” as a Potent Inhibitor of Glucosidase (1970)

Journal Article "Nojirimycin" as a Potent Inhibitor of Glucosidase Get access Tomizo Niwa, Tomizo Niwa Central Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama Search for other works by this author on: Oxford Academic Google Scholar Sigeharu Inouye, Sigeharu Inouye Central Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama Search for other works by this author on: Oxford Academic Google Scholar Takashi Tsuruoka, Takashi Tsuruoka Central Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama Search for other works by this author on: Oxford Academic Google Scholar Yoshihisa Koaze, Yoshihisa Koaze Central Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama Search for other works by this author on: Oxford Academic Google Scholar Taro Niida Taro Niida Central Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 34, Issue 6, 1 June 1970, Pages 966–968, https://doi.org/10.1080/00021369.1970.10859713 Published: 01 June 1970 Article history Received: 26 February 1969 Published: 01 June 1970
Robot DE NIRO: A Human-Centered, Autonomous, Mobile Research Platform for Cognitively-Enhanced Manipulation (2020)

We introduce <i>Robot DE NIRO</i>, an autonomous, collaborative, humanoid robot for mobile manipulation. We built DE NIRO to perform a wide variety of manipulation behaviors, with a focus on pick-and-place tasks. DE NIRO is designed to be used in a domestic environment, especially in support of caregivers working with the elderly. Given this design focus, DE NIRO can interact naturally, reliably, and safely with humans, autonomously navigate through environments on command, intelligently retrieve or move target objects, and avoid collisions efficiently. We describe DE NIRO's hardware and software, including an extensive vision sensor suite of 2D and 3D LIDARs, a depth camera, and a 360-degree camera rig; two types of custom grippers; and a custom-built exoskeleton called DE VITO. We demonstrate DE NIRO's manipulation capabilities in three illustrative challenges: First, we have DE NIRO perform a fetch-an-object challenge. Next, we add more cognition to DE NIRO's object recognition and grasping abilities, confronting it with small objects of unknown shape. Finally, we extend DE NIRO's capabilities into dual-arm manipulation of larger objects. We put particular emphasis on the features that enable DE NIRO to interact safely and naturally with humans. Our contribution is in sharing how a humanoid robot with complex capabilities can be designed and built quickly with off-the-shelf hardware and open-source software. Supplementary Material including our code, a documentation, videos and the CAD models of several hardware parts are openly available at https://www.imperial.ac.uk/robot-intelligence/software/.
Asynchronous multicarrier multiple access: Optimal and sub-optimal detection and decoding (2003)

In this paper, we describe multicarrier multiple access architectures that are based on combining filtered multicarrier modulation with multiplexing of sub-carriers across distinct users. These architectures can be deployed for both uplink and downlink wireless communications. We focus on the more critical uplink where multiple users share an asynchronous channel. Signals belonging to distinct users experience time and carrier frequency asynchronism and propagate through independent frequency-selective fading channels. In such a scenario the receiver sees intersymbol interference, intercarrier interference, and multiple access interference components that are a function of the propagation conditions, the design of the sub-channel transmit filters, and the tone allocation strategy. We formulate the optimal multicarrier multiuser detector that yields minimum probability of error. Then, we devise sub-optimal (simplified) detection approaches. These detectors are soft-in soft-out modules that can be concatenated with the channel decoders when the users' information signals are channel encoded. In such a case, practical decoding can be performed by the iterative concatenation of multicarrier detection and decoding (turbo multiuser decoding).
Control of Bleeding in Endoscopic Sinus Surgery: Use of a Novel Gelatin-Based Hemostatic Agent (2002)

FloSeal is a safe and effective treatment for controlling blood loss after EES. It may also provide support to the middle meatus as well as improve healing of the operative site compared with the use of traditional nasal packing. However, randomized clinical trials are needed to further evaluate this.
The R+-Tree: A Dynamic Index for Multi-Dimensional Objects (2018)

The problem of indexing multidimensional objects is considered. First, a classification of existing methods is given along with a discussion of the major issues involved in multidimensional data indexing. Second, a variation to Guttman’s R-trees (R+-trees) that avoids overlapping rectangles in intermediate nodes of the tree is introduced. Algorithms for searching, updating, initial packing and reorganization of the structure are discussed in detail. Finally, we provide analytical results indicating that R+-trees achieve up to 50% savings in disk accesses compared to an R-tree when searching files of thousands of rectangles.