gebhart/patrepeval huggingface dataset:
Possible Artefacts in the in vitro Determination of Antimalarial Activity of Natural Products that Incorporate into Lipid Bilayer: Apparent Antiplasmodial Activity of Dehydroabietinol, a Constituent of Hyptis suaveolens (2002)

Dehydroabietinol isolated from Hyptis suaveolens (L.) Poit. was found to inhibit growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM). However, erythrocytes exposed to dehydroabietinol were transformed in a dose-dependent manner towards spherostomatocytic forms with concomitant formation of endovesicles, as disclosed by transmission electron microscopy. The erythrocyte shape alterations caused by dehydroabietinol correlated well with its apparent IC 50 value. Thus, dehydroabietinol incorporates into the erythrocyte membrane, and since invasion and survival of Plasmodium parasites is known to depend on the function of the erythrocyte membrane, the observed antiplasmodial effect of dehydroabietinol is presumably an indirect effect on the host cell. Because of these findings, microscopic investigations should be generally used to support claims of antimalarial effects of apolar natural products.
Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 2. Synthesis of polynucleotides (1955)

Research Article| May 01 1955 Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 2. Synthesis of polynucleotides L. A. Heppel; L. A. Heppel 1Agricultural Research Council Plant Virus Research Unit, Molteno Institute, University of Cambridge Search for other works by this author on: This Site PubMed Google Scholar P. R. Whitfeld; P. R. Whitfeld 1Agricultural Research Council Plant Virus Research Unit, Molteno Institute, University of Cambridge Search for other works by this author on: This Site PubMed Google Scholar R. Markham R. Markham 1Agricultural Research Council Plant Virus Research Unit, Molteno Institute, University of Cambridge Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1955) 60 (1): 8–15. https://doi.org/10.1042/bj0600008 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share MailTo Twitter LinkedIn Cite Icon Cite Get Permissions Citation L. A. Heppel, P. R. Whitfeld, R. Markham; Nucleotide exchange reactions catalysed by ribonuclease and spleen phosphodiesterase. 2. Synthesis of polynucleotides. Biochem J 1 May 1955; 60 (1): 8–15. doi: https://doi.org/10.1042/bj0600008 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1955 CAMBRIDGE UNIVERSITY PRESS1955 Article PDF first page preview Close Modal You do not currently have access to this content.
The Finapres 2300e finger cuff (1993)

Blood pressure measurements associated with malapplication of a finger cuff were compared with contemporaneous intra-arterial pressure data in seven volunteers to determine the influence of cuff application on the accuracy of the Finapres 2300e. Systolic readings in all cuff positions differed from arterial line data by more than the recommended standard and tight and loose cuff applications under and over-read respectively, in all subjects. The results show the Finapres to be sensitive to small degrees of finger cuff malapplication which contribute to the bias on direct arterial comparison and limit the reliability of the instrument in clinical practice.
A survey on the reliability of power electronics in electro-mobility applications (2015)

Reliability is an important issue in the field of power electronics since most of the electrical energy is today processed by power electronics. In most of the electro-mobility applications, e.g. electric and hybrid-electric vehicles, power electronic are commonly used in very harsh environment. Temperature variations, vibration and also the stresses affecting the device (which can come even from the device itself or from external sources) and may cause unreliable system. Thus, designing reliable power electronic components is important for the aim of reducing the energy losses, maintenance cost and extending the service lifetime as well. Research within power electronics is of high interest as it has an important impact in the industry of the electro-mobility applications. According to the aforementioned explanations, this paper will provide an overview of the common factors (thermal cycles, power cycles, vibrations, voltage stress and current ripple stress) affecting the reliability of power electronics in electro-mobility applications. Also, the researchers perspective is summarized from 2001 to 2015.
Structural Health Monitoring of a rotor blade during statical load test (2007)

The paper describes a structural health monitoring concept based on the evaluation of acoustic Lamb waves. Using a suitable damage indicator like the correlation coefficient it is possible to detect and localize defects in the observed structure. The functional capability was shown in statical test of a part of a rotor blade.
Packaging of multibeam spatially-fed antenna arrays (2004)

Discrete lens antenna arrays (DLAs) have been introduced for multibeam applications. In a DLA, two antenna arrays, in which element pairs are connected with true time-delay lines of varying length across the array, perform a discrete spatial Fourier transform. The lens array produces a focal surface along which feed antennas are placed, each corresponding to a beam in a different direction. The DLA can be used to transmit, receive or both. The DLA is a three-dimensional device with planar, typically multilayer, lens antennas, and a curved focal surface. Packaging the feed antennas along the focal surface needs to be solved, and some issues related to this problem are the focus of the paper. Radiation patterns of feed antenna elements have been measured with and without an absorber placed in the focal volume. A package has been designed to house over 20 beam feeds for a lens array to be used an X-band satellite ground station application.
A Singularly Valuable Decomposition: The SVD of a Matrix (1996)

Click to increase image sizeClick to decrease image size Additional informationNotes on contributorsDan KalmanDan Kalman is an assistant professor at American University in Washington, DC. From 1985 to 1993 he worked as an applied mathematician in the aerospace industry. It was during that period that he first learned about the SVD and its applications. He is very happy to be teaching again and is avidly following all the discussions and presentations about the teaching of linear algebra.
Peripheral Arterial Tonometry for Risk Stratification in Men With Coronary Artery Disease (2010)

Measurement of peripheral microvascular endothelial function with PAT may be able to distinguish high-risk men from moderate- and low-risk men with stable CAD and well-controlled LDL-C levels and thus aid in residual risk stratification in this at risk cohort.
Silver Alloy Coated Catheters Reduce Catheter‐associated Bacteriuria (1990)

The tendency of indwelling catheters to cause urinary tract infection was evaluated in a randomised clinical study of 223 patients. A Foley catheter coated with silver alloy on both inner and outer surfaces was used in 60 patients; 60 others received a Teflonised latex Foley's catheter and the remaining 103 patients were excluded because of antibiotic treatment, diabetes, etc. There was a statistically significant difference in the incidence of catheter-associated bacteriuria (greater than 10(5) organisms/ml) in the 2 groups after 6 days' catheterisation: 6 patients with the silver coated catheter developed bacteriuria compared with 22 who had the Teflonised latex catheter. This suggests that the silver impregnated urethral catheters reduce the incidence of catheter-associated urinary tract infection.
Chemical and Nutritional Constituents of Sea Buckthorn Juice (2004)

Sea buckthorn juice is one of the imperative product obtained from the sea buckthorn berries, is now commercially very important. The juice provides a nutritious beverage, high in suspended solids, and very high in vitamins especially in vitamin C and carotenoids. It contains different kinds of nutrients and bioactive substances including vitamins, fatty acids, free amino acids and elemental components. These components vary substantially among individuals, populations, origins or subspecies. The available compositional data regarding sea buckthorn juice is tabulated to produce a comprehensive source of recent information on chemical and medicinally important constituents of different origin and varieties. The presence of valuable chemical and nutritionally important constituents in sea buckthorn juice, and from the scientific knowledge of their importance, it is clear that sea buckthorn juice is one of the most important source of these materials, and can be use as alternative nutritional sources in the commercial market.
Extending Network Lifetime of Wireless Sensor Networks (2015)

One critical issue in designing and managing a wireless sensor network is how to save the energy consumption of the sensors in order to maximize network lifetime under the constraint of full coverage of the monitored targets. In this paper, we adopt the common approach of creating disjoint sensor covers to prolong network lifetime. The typical goal used in the literature is to maximize the number of covers without consideration of the energy levels of the sensors. We argue that the network lifetime can be extended by maximizing the total bottleneck energy of the created covers. We formally define the problem of maximizing the total bottleneck energy of the covers, present for the first time an integer programming formulation of the problem, and develop two algorithms to solve large problem instances. Extensive experimental tests show that the use of the goal of maximizing the total bottleneck energy of the covers creates covers with substantially longer network lifetime than the lifetime of the covers created with the goal of maximizing solely the number of covers.
Wearable Patient Monitoring Application (ECG) using Wireless Sensor Networks (2006)

In this paper, we discuss a design for a wearable electrocardiograph device constructed with small, low-powered "mote" sensors for use in wireless sensor networks. A wearable, wireless three-lead electrocardiograph sensor module is utilized and the initial tests are presented that illustrate the viability of this design. This device can be integrated into a suite of wearable wireless sensors used for patient monitoring and other applications
Comparison of Helicobacter pylori and attaching-effacing Escherichia coli adhesion to eukaryotic cells (1993)

Adhesion of Helicobacter pylori was reported previously to be morphologically identical to "attaching and effacing" Escherichia coli. Therefore, the aim of the present study was to define the adhesion phenotype of H. pylori LC-11 to HEp-2, KATO-III, HEL, and CHO tissue culture cells. By using both staining of F-actin with fluorescein-labeled phalloidin and ultrastructural analysis, diffuse bacterial adhesion to discrete microvillus-denuded regions of the plasma membrane was observed in each of the infected cell lines. However, strain LC-11 did not induce formation of F-actin adhesion pedestals on the eukaryotic cells. H. pylori was negative by colony blot hybridization with an E. coli attaching and effacing gene probe. Elevations in inositol triphosphates followed infection of HEp-2 cells with H. pylori (405% of control values +/- 147%; P < 0.05). To correlate the observed histopathology with expression of the H. pylori phosphatidylethanolamine receptor, a thin-layer chromatography overlay-binding assay was used to identify receptors in each of the cell lines. H. pylori adhered to eukaryotic cells regardless of the presence (HEp-2, KATO-III, and CHO cells) or absence (HEL cells) of the lipid receptor as detected under the assay conditions. However, in comparison to cell lines that possess the phosphatidylethanolamine receptor, HEL cells demonstrated less quantitative H. pylori binding. These findings suggest that mechanisms distinct from E. coli enteropathogens underlie the adhesion of H. pylori to mucosal surfaces. In addition to the phosphatidylethanolamine H. pylori receptor, another host factor(s) likely mediates the attachment of H. pylori to human eukaryotic cells.
Practical Speech Emotion Recognition Based on Online Learning: From Acted Data to Elicited Data (2013)

We study the cross-database speech emotion recognition based on online learning. How to apply a classifier trained on acted data to naturalistic data, such as elicited data, remains a major challenge in today’s speech emotion recognition system. We introduce three types of different data sources: first, a basic speech emotion dataset which is collected from acted speech by professional actors and actresses; second, a speaker-independent data set which contains a large number of speakers; third, an elicited speech data set collected from a cognitive task. Acoustic features are extracted from emotional utterances and evaluated by using maximal information coefficient (MIC). A baseline valence and arousal classifier is designed based on Gaussian mixture models. Online training module is implemented by using AdaBoost. While the offline recognizer is trained on the acted data, the online testing data includes the speaker-independent data and the elicited data. Experimental results show that by introducing the online learning module our speech emotion recognition system can be better adapted to new data, which is an important character in real world applications.
Physiological Responses of Embryonic Heermann's Gulls to Temperature (1979)

Oxygen consumption, heart rate, and thermal tolerance were measured in week-old embryos of Heermann's gull (Larus heermanni). Heart rate and oxygen consumption are temperature independent between 30 and 40 C and average 120 beats/min and 1.87 cm³ O₂/(egg·h). Below 30 C, these rate processes become strongly temperature dependent, and the heart stops beating when cooled to 7-13 C. The beat recovers when the embryo is rewarmed, even after 1 h at 6 C. The heart beat stops when the embryo is heated above 40.0-41.6 C but recovers with cooling. However, the beat does not recover after the embryo has been heated to 43 C for 1 h. The thermal independence of embryonic function over the 30-40 C range minimizes disruptions associated with variation of temperature during incubation. Unattended eggs at night may chill to temperatures which cause cessation of heart beat, but such exposure is not lethal if the eggs are rewarmed. Exposure to radiant heat during the day can rapidly raise egg temperature to levels which kill the embryo. Thus, an important aspect of incubation by adult Heermann's gulls is shading of the eggs and prevention of overheating.
A Cached Registration Scheme for IP Multimedia Subsystem (IMS) (2014)

IP Multimedia Subsystem (IMS), an architectural framework for delivering multimedia services, was standardized by 3GPP/3GPP2. It is integrated with 4G and will most likely be with 5G and beyond, so as to enable wireless carriers to provide rich multimedia services, such as IPTV, chat, push to talk, and video conference. To use these services, users need to perform registration procedure with IMS, which will provide user information to the system. Registration is also performed when users move from one network to another. Due to the complexity of IMS and the increasing demands for these services, a key challenge IMS faces is to provide QoS to meet user requirements. One of the key performance factors is delay encountered in registration and service establishment. Also, users'mobility impacts the rate of registration and consequently the signaling generated that must be handled by the system. This work proposes and analyzes a cached registration scheme to reduce the delay associated with registration. The work also examines the effects of different mobility models on the application layer, in particular IMS. The work studies the impact of user movement patterns on the system and examines the impact of the proposed cached registration scheme on these patterns.
Sputtering Process Model of Deposition Rate (1979)

A model of the sputtering process has been developed that predicts the deposition rate of a sputtering system with parallel-plate geometry. By using data for sputtering yield vs voltage obtained from an ion-beam sputtering system, the model applies a new theory for computing the backscatter of the sputtered material, and, from the results, predicts deposition rates. The model also considers the effects of charge exchange in the sheaths, and of re-emission of sputtered material at the substrate. The model is valid for magnetic, tuned substrate, driven substrate, and controlled area ratio diode systems. Comparison with observed deposition rates shows good agreement for clean systems. An experimental APL program that uses the model has been written.
Needle biopsies of pulmonary lesions (1978)

This review is based on 5300 needle biopsies. Complications and their precaution are discussed. Pneumothorax seldom has to be treated. Hemoptysis and small local bleeding are of no clinical significance. Tumor cell spread and air embolism may occur but extremely rarely. Indications, contraindications equipment, and biopsy technique are treated. A recent technical improvement in needle biopsy is described.
The Variations in Serum Uric Acid During 24 Hours and from Day to Day (1957)

(1957). The Variations in Serum Uric Acid During 24 Hours and from Day to Day. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 9, No. 3, pp. 244-248.
Limited access testing: IEEE 1149.4-instrumentation and methods (2002)

The IEEE 1149.4 standard is now poised for inclusion in a new generation of products. Successful application of this important new standard will depend on the availability of supporting methods and instrumentation. While the standard supplies a common architecture, the test engineer must now supply both method and instrumentation. This paper describes proven instrumentation concepts used to demonstrate IEEE 1149.4 measurements on the MEI test chip. Additionally, the paper discusses how current-stimulus and voltage-measurement techniques can be used to diagnose faulty components in medium sized networks of 75 to 150 components. IEEE 1149.4 tests can be automatically generated rather than hand crafted as in functional testing. Unlike digital resting, the technique does not use fault models. Correct operation is found by examining the deviation from nominal performance, greatly simplifying the test development task.
Mozart K.545 Mimics Mozart K.448 in Reducing Epileptiform Discharges in Epileptic Children (2012)

Mozart K.448 has been shown to improve cognitive function, leading to what is known as the Mozart Effect. Our previous work reveals positive effects of Mozart K.448 in reducing epileptiform discharges in epileptic children. In this study, we evaluated the effect of Mozart K.545 and compared the effects with those of Mozart K.448 on epileptiform discharges in children with epilepsy. Thirty-nine epileptic children with epileptiform discharges were included in the study. They received electroencephalogram examinations before, during, and after listening to Mozart K.448 and K.545, one week apart, respectively. The frequencies of epileptiform discharges were compared. There was a significant decrease in the frequency of epileptiform discharges during and right after listening to Mozart K.448 and K.545 (reduced by 35.7 ± 32.7% during Mozart K.448 and 30.3 ± 44.4% after Mozart K.448; and 34.0 ± 39.5% during Mozart K.545 and 31.8 ± 39.2% after Mozart K.545). Spectrogrammatic analysis of the two pieces of music demonstrated that both share similar spectrogrammatic characteristics. Listening to Mozart K.448 and K.545 decreased the epileptiform discharges in epileptic children. This suggests that Mozart K.448 is not the only piece of music to have beneficial effects on children with epilepsy. Other music with lower harmonics may also decrease epileptiform discharges in epileptic children.
On a modeling of voltage-application to metallic electrodes using density functional theory (1997)

With the ultimate purpose of designing molecule/surface interaction potentials for the dynamical study of electropolymerization reactions, a theoretical framework, based on density functional theory (DFT), is proposed to obtain in a self-consistent manner the true electronic density of a metallic surface set under an applied voltage. A direct link is made between the DFT chemical potential μ and the (experimental) electrode potential drop Δε imposed in electrochemical experiments. An emphasis is made on the possibility of using cluster models to describe polarized surfaces. It is found that within “experimental” applied voltages, the induced surface charges may be lower that previously expected. This suggests that the electrostatic component in molecule/polarized-surface interaction potentials may not be overwhelmingly important towards other terms such as polarization, dispersion or even quantum contributions. In this respect, the μ=f(Δε) equation suggests that the Lewis acidic or basic character of a metallic surface can be monitored continuously by simply tuning the electrode potential drop. Possible experimental verifications of this proposal are examined.
People detection based on co-occurrence of appearance and spatiotemporal features (2008)

This paper presents a method for detecting people based on the co-occurrence of appearance and spatiotemporal features. Histograms of oriented gradients(HOG) are used as appearance features, and the results of pixel state analysis are used as spatiotemporal features. The pixel state analysis classifies foreground pixels as either stationary or transient. The appearance and spatiotemporal features are projected into subspaces in order to reduce the dimensions of the vectors by principal component analysis(PCA). The cascade AdaBoost classifier is used to represent the co-occurrence of the appearance and spatiotemporal features. The use of feature co-occurrence, which captures the similarity of appearance, motion, and spatial information within the people class, makes it an effective detector. Experimental results show that the performance of our method is about 29% better than that of the conventional method.
Natural antibodies against the carcinoembryonic antigen (CEA) and a related antigen, NCA, in human sera. (1988)

Natural antibodies directed against CEA and a related antigen, NCA, have been demonstrated in all normal and pathological sera using an EIA, although they have never been detected by RIA. These antibodies are not anti-blood group antibodies, as their titer was decreased only slightly by absorption with blood group substances. The study of their reactivity with deglycosylated antigens demonstrated that they were directed against peptidic epitopes. Antibodies against NCA or CEA, purified using specific immunosorbents, cross-reacted with all the antigens of the "CEA family" but not or only weakly with unrelated antigens.