gebhart/patrepeval huggingface dataset:
Modified Procedure for Determination of Protein-Bound Iodine in Serum (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModified Procedure for Determination of Protein-Bound Iodine in SerumHarry Sobel and S. SapsinCite this: Anal. Chem. 1952, 24, 11, 1829–1831Publication Date (Print):November 1, 1952Publication History Published online1 May 2002Published inissue 1 November 1952https://pubs.acs.org/doi/10.1021/ac60071a034https://doi.org/10.1021/ac60071a034research-articleACS PublicationsRequest reuse permissionsArticle Views17Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Acetylcholinesterase Clustering at the Neuromuscular Junction Involves Perlecan and Dystroglycan (1999)

Formation of the synaptic basal lamina at vertebrate neuromuscular junction involves the accumulation of numerous specialized extracellular matrix molecules including a specific form of acetylcholinesterase (AChE), the collagenic-tailed form. The mechanisms responsible for its localization at sites of nerve- muscle contact are not well understood. To understand synaptic AChE localization, we synthesized a fluorescent conjugate of fasciculin 2, a snake alpha-neurotoxin that tightly binds to the catalytic subunit. Prelabeling AChE on the surface of Xenopus muscle cells revealed that preexisting AChE molecules could be recruited to form clusters that colocalize with acetylcholine receptors at sites of nerve-muscle contact. Likewise, purified avian AChE with collagen-like tail, when transplanted to Xenopus muscle cells before the addition of nerves, also accumulated at sites of nerve-muscle contact. Using exogenous avian AChE as a marker, we show that the collagenic-tailed form of the enzyme binds to the heparan-sulfate proteoglycan perlecan, which in turn binds to the dystroglycan complex through alpha-dystroglycan. Therefore, the dystroglycan-perlecan complex serves as a cell surface acceptor for AChE, enabling it to be clustered at the synapse by lateral migration within the plane of the membrane. A similar mechanism may underlie the initial formation of all specialized basal lamina interposed between other cell types.
Levels of coenzyme Q10 in asthmatics. (2002)

Our results suggest possible contribution of suboptimal concentrations of CoQ10 on antioxidative dysbalance in As and provide rationale for its supplementation with clinical evaluation. (Tab. 2, Fig. 1, Ref. 39.).
An experimental study of turbulent skin friction reduction in supersonic flow using a microblowing technique (2000)

A new turbulent skin friction reduction technology, called the microblowing technique has been tested in supersonic flow (Mach number of 1.9) on specially designed porous plates with microholes. The skin friction was measured directly by a force balance and the boundary layer development was measured by a total pressure rake at the tailing edge of a test plate. The free stream Reynolds number was 1.0(10 exp 6) per meter. The turbulent skin friction coefficient ratios (C(sub f)/C(sub f0)) of seven porous plates are given in this report. Test results showed that the microblowing technique could reduce the turbulent skin friction in supersonic flow (up to 90 percent below a solid flat plate value, which was even greater than in subsonic flow).
Delay analyses of wavelength reservation methods for high-speed burst transfer in photonic networks (1999)

It is possible to offer a high-speed data transfer capability by employing WDM technology. One promising method is to transfer the data through a fast wavelength reservation. However, the wavelength reservation time, including the propagation delay between source and receiver nodes, becomes large, which may lead to performance degradation. We develop a new approximate analytical method, which incorporates wavelength reservation times. We consider two methods for wavelength reservation; a forward method in which wavelength reservation is performed along the forward path from source to receiver, and a backward method in which it is performed along the backward path. Based on our approximate analysis, we investigate the effects of propagation delays on both methods.
Power sources for nanotechnology (2004)

Nanoscale power sources are critical to the success of nanodevices. Potential nanotechnology applications range from molecular electronics to medical treatment to remote sensing. Despite the limited research to date and the complexities of the problem, nanoscale power sources may be developed with inspiration from microscale and molecular/biological power sources, and they can be fabricated with new and emerging fabrication techniques. Recent progress toward microscale power is surveyed herein, and limitations are noted. Finally, several nanoscale power source schemes are described which can provide direction for future research efforts.
Staggered-lineup heterojunctions as sources of tunable below-gap radiation: Experimental verification (1984)

We report experimental verification of the prediction of widely bias-tunable below-gap luminescence, from lattice-matched (p) (Al,In)As/ (n) InP heterojunctions, a system that has been predicted to have staggered lineup. The diodes, grown by molecular beam epitaxy, exhibit strong luminescence at 1.4 K, with a peak energy that shifts from 0.97 to 1.04 eV as the (pulsed) current density is increased from 4.5 to 40 A/cm2. Nonshifting injection luminescence at 1.4 eV, due to hole injection into the n-InP substrate, was also present, but appreciably weaker (&lt;25%) than the interface luminescence. The spectra indicate that the band lineup in the (Al,In)As/InP system is indeed staggered, with a residual gap at the interface close to 0.96 eV. The corresponding conduction and valence-band offsets are 0.52 and 0.40 eV.
p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death (2005)

In large models of neuronal cell death, there is a tight correlation between Cdk5 deregulation and cell-cycle dysfunction. However, pathways that link Cdk5 to the cell cycle during neuronal death are still unclear. We have investigated the molecular events that precede p25/Cdk5-triggered neuronal death using a neuronal cell line that allows inducible p25 expression. In this system, no sign of apoptosis was seen before 24 hours of p25 induction. Thus, at that time, cell-cycle-regulatory proteins were analysed by immunoblotting and some of them showed a significant deregulation. Interestingly, after time-course experiments, the earliest feature correlated with p25 expression was the phosphorylation of the retinoblastoma protein (Rb). Indeed, this phosphorylation was observed 6 hours after p25 induction and was abolished in the presence of a Cdk5 inhibitor, roscovitine, which does not inhibit the usual Rb cyclin-D kinases Cdk4 and Cdk6. Furthermore, analyses of levels and subcellular localization of Cdk-related cyclins did not reveal any change following Cdk5 activation, arguing for a direct effect of Cdk5 activity on Rb protein. This latter result was clearly demonstrated by in vitro kinase assays showing that the p25-Cdk5 complex in our cell system phosphorylates Rb directly without the need for any intermediary kinase activity. Hence, Rb might be an appropriate candidate that connects Cdk5 to cell-cycle deregulation during neuronal cell death.
Enzyme formation and polysaccharide synthesis by bacteria (1935)

IT is only comparatively recently that precise knowledge has been obtained in regard to the important problem of polysaccharide synthesis by bacteria. This advance has been due to the work of Hibbert and co-workers , who succeeded in isolating in the pure state and also on a large scale the poly- saccharides formed by the activity of the micro-organisms B. mesentericUs, B. subtilis, and Acetobacter xylinum, and ascertaining their chemical structure.
A new p-channel bidirectional trench power MOSFET for battery charging and protection (2010)

A new p-channel bidirectional power MOSFET (Bi-DFET) for 15–30V battery charging applications is detailed. A specially-designed bidirectional trench MOSFET was built on chip with lateral PMOS devices that connect the trench FET body to the source/drain terminal of the highest potential. Bi-DFET prototypes had greater than 2.5X lower specific on-resistance than two back-to-back standard trench MOSFETs, which are commonly used in bidirectional sockets. Thus this device is very promising for reducing the device size in “space sensitive” applications.
Low‐power quadrature modulator ICs for digital mobile communications (1994)

Abstract Low‐power monolithic quadrature modulators for digital mobile communication have been realized for 800‐MHz and 140‐MHz bands. Considering the application to ultrasmall portable telephones, the design reduces the power consumption drastically and realizes a complete one‐chip configuration with no adjustments or external parts. For this purpose, several proposals are made for the circuit configuration. First, a total configuration using a constant phasedifference‐type 90° combiner is proposed to reduce the circuit size and chip area dramatically and to eliminate the phase adjustments. Next, for a double balance mixer (DBM) which is the key for modulation characteristics, an analog‐switch‐type DBM is used for the 800‐MHz band and realizes a highly accurate modulation wave without the influence of device variation due to the semiconductor fabrication process. Furthermore, a bootstraptype buffer amplifier with high current utilization has been devised for the output stage. The fabricated 800‐MHz band (GaAs) and 140‐MHz band (Si) quadrature modulator integrated circuits (ICs) have shown superior performance as π/4 shift QPSK modulators. the power consumption is 65 mW and 32.5 mW, respectively, realizing a dramatically low power compared to conventional methods.
UV Dose Governs UV-Polymerized Polyacrylamide Hydrogel Modulus (2017)

Polyacrylamide (PAA) hydrogels have become a widely used tool whose easily tunable mechanical properties, biocompatibility, thermostability, and chemical inertness make them invaluable in many biological applications, such as cell mechanosensitivity studies. Currently, preparation of PAA gels involves mixtures of acrylamide, bisacrylamide, a source of free radicals, and a chemical stabilizer. This method, while generally well accepted, has its drawbacks: long polymerization times, unstable and toxic reagents, and tedious preparation. Alternatively, PAA gels could be made by free radical polymerization (FRP) using ultraviolet (UV) photopolymerization, a method which is quicker, less tedious, and less toxic. Here, we describe a simple strategy based on total UV energy for determining the optimal UV crosslinking conditions that lead to optimal hydrogel modulus.
Studies on Alkylated Furan Derivatives. V (1960)

As the alkylated derivatives of 5-nitrofuran and its allied compounds, 5-nitro-2-furaldehyde 4-alkylsemicarbazone and 4-alkylthiosemicarbazones were prepared. None of these compounds showed antitubercular activity but some of the compounds had growth-inhibitory action against Trichophyton and Microsporum spp. at low concentration. None of the compounds were effective against Candida and Saccharomyces.
The Safety of the Esmarch Tourniquet (1993)

The use of an Esmarch bandage as a tourniquet in surgery has been criticized. Many authors claim that the pressures under the Esmarch are inconsistent and may be extremely high. We have seen few, if any, problems from the use of an Esmarch in surgery of the foot and ankle. The purpose of this study was to evaluate the pressures generated under the Esmarch tourniquet in a situation that mimics its clinical application, and to determine whether pressures of appropriate magnitude and consistency are obtained in order to recommend its continued use in surgery. Ten volunteers performed numerous applications of the Esmarch. The number of wraps and the width of the Esmarch bandage used were varied. The Esmarch was applied as it would be for a surgical case. Pressures directly beneath the Esmarch were recorded 8 cm proximal to the distal tip of the medial malleolus. Considering all volunteers and all pressures generated, a 3-in Esmarch applied with three wraps gave a mean pressure (+/- SD) of 225 +/- 46 mm Hg. A 3-in Esmarch applied with four wraps gave a mean pressure of 291 +/- 53 mm Hg. A 4-in Esmarch applied with three wraps gave a mean pressure of 233 +/- 35 mm Hg, and a 4-in Esmarch with four wraps gave a mean pressure of 284 +/- 42 mm Hg. The maximum pressures generated by any individual were as follows: 3-in three wraps, 321 mm Hg; 3-in four wraps, 413 mm Hg; 4-in three wraps, 328 mm Hg; and 4-in four wraps, 380 mm Hg.(ABSTRACT TRUNCATED AT 250 WORDS)
Effect of Applying Lactic Acid Bacteria Isolated from Forage Crops on Fermentation Characteristics and Aerobic Deterioration of Silage (1999)

Two selected strains, Lactobacillus casei FG 1 and Lactobacillus plantarum FG 10 that were isolated from forage crops were used as additives at 1.0 x 10(5) cfu/g of fresh matter to alfalfa, Italian ryegrass, and sorghum, and their effect on fermentation characteristics and aerobic deterioration of silage was studied. The three silages treated with strains FG 1 or FG 10 were well preserved; had significantly lower pH values, butyric acid, propionic acid, and ammonia N concentrations, gas production, and dry matter losses; and had significantly higher contents of residual water-soluble carbohydrates and lactic acid than did the respective control silages. Yeast counts were high in all treated silages and increased rapidly during aerobic exposure. As a result, treated silages spoiled faster upon aerobic exposure than did the respective control silages. Most yeasts isolated from deteriorated silages showed high tolerance to lactic acid but low tolerance to butyric acid, and they were able to grow at low pH conditions and assimilate lactic acid. The results confirmed that L. casei and L. plantarum improved fermentation quality but did not inhibit the growth of silage yeast or aerobic deterioration of the silage.
Autologous Collagen Dispersion (Autologen) as a Dermal Filler (2000)

Our trial suggests that autologous collagen dispersion may represent a viable alternative to bovine collagen. Clinical persistence and histologic behavior of Autologen appear to be at least as favorable as those of Zyplast, and Autologen obviates the need for allergy testing and eliminates the possibility of disease transmission. Arch Facial Plast Surg. 2000;2:48-52
IRAC: Mode of action classification and insecticide resistance management (2014)

Insecticide resistance is a long standing and expanding problem for pest arthropod control. Effective insecticide resistance management (IRM) is essential if the utility of current and future insecticides is to be preserved. Established in 1984, the Insecticide Resistance Action Committee (IRAC) is an international association of crop protection companies. IRAC serves as the Specialist Technical Group within CropLife International focused on ensuring the long term efficacy of insect, mite and tick control products through effective resistance management for sustainable agriculture and improved public health. A key function of IRAC is the continued development of the Mode of Action (MoA) classification scheme, which provides up-to-date information on the modes of action of new and established insecticides and acaricides and which serves as the basis for developing appropriate IRM strategies for crop protection and vector control. The IRAC MoA classification scheme covers more than 25 different modes of action and at least 55 different chemical classes. Diversity is the spice of resistance management by chemical means and thus it provides an approach to IRM providing a straightforward means to identify potential rotation/alternation options.
Comparison of Spheroids Formed by Rat Glioma Stem Cells and Neural Stem Cells Reveals Differences in Glucose Metabolism and Promising Therapeutic Applications (2012)

Cancer stem cells (CSCs) are thought to be partially responsible for cancer resistance to current therapies and tumor recurrence. Dichloroacetate (DCA), a compound capable of shifting metabolism from glycolysis to glucose oxidation, via an inhibition of pyruvate dehydrogenase kinase was used. We show that DCA is able to shift the pyruvate metabolism in rat glioma CSCs but has no effect in rat neural stem cells. DCA forces CSCs into oxidative phosphorylation but does not trigger the production of reactive oxygen species and consecutive anti-cancer apoptosis. However, DCA, associated with etoposide or irradiation, induced a Bax-dependent apoptosis in CSCs in vitro and decreased their proliferation in vivo. The former phenomenon is related to DCA-induced Foxo3 and p53 expression, resulting in the overexpression of BH3-only proteins (Bad, Noxa, and Puma), which in turn facilitates Bax-dependent apoptosis. Our results demonstrate that a small drug available for clinical studies potentiates the induction of apoptosis in glioma CSCs.
Recent Progress in Forward Error Correction for Optical Communication Systems (2005)

The history of forward error correction in optical communications is reviewed. The various types of FEC are classified as belonging to three generations. The first generation FEC represents the first to be successful in submarine systems, when the use of RS(255, 239) became widespread as ITU-T G.975, and also as G.709 for terrestrial systems. As WDM systems matured, a quest began for a stronger second generation FEC. Several types of concatenated code were proposed for this, and were installed in commercial systems. The advent of third-generation FEC opened up new vistas for the next generation of optical communication systems. Thanks to soft decision decoding and block turbo codes, a net coding gain of 10.1 dB has been demonstrated experimentally. That brought us a number of positive impacts on existing systems. Each new generation of FEC was compared in terms of the ultimate coding gain. The Shannon limit was discussed for hard or soft decision decoding. Several functionalities employing the FEC framing were introduced, such as overall wrapping by the FEC frame enabling the asynchronous multiplexing of different clients' data. Fast polarization scrambling with FEC was effective in mitigating polarization mode dispersion, and the error monitor function proved useful for the adaptive equalization of both chromatic dispersion and PMD.
Upstream influence on turbulent jet flows from cruciform nozzles (1985)

The mixing of single or multiple jets is relevant in several engineering applications ranging from flame stabilisation in combustion to high lift devices for V/STOL aircraft. In some of these applications, expeditious manufacturing and ease of installation may dictate the use of sharp-edged slots in preference to nozzles with contoured upstream shaping. It has been suggested that cruciform nozzle exit shapes may be suitable for improving mixing and thus thrust augmentation in STOL aircraft. The effects of nozzle geometry on the performance of an axisymmetric thrust augmentor have been investigated experimentally and a very slight improvement in the performance of the axisymmetric thrust augmentor was observed when cruciform nozzles were used after the tests had been performed with circular nozzles.
Flip Chip Assembly of a 40-60 GHz GaAs MicrostripAmplifier (2004)

This paper describes the successful flip chip assembly of a broadband GaAs amplifier in microstrip design. The flip chip technology used was thermo compression (TC) flip chip bonding of the MMICs to gold ball bumps bonded on the thin film patterned alumina carrier. Also, we report on the occurrence of parasitic parallel plate (PPL) modes in the assemblies and we propose and investigate a scheme to eliminate the modes which, to the best our knowledge, have not been reported on before. Finally we introduce our own flip chip transition equivalent circuit and we use this model in ADS to compare the simulated results with measurements. It is fair to say that the equivalent circuit models the flip chip transition well. This work was performed in the European MEDEA+ packaging project HIMICRO.
[Clinical experiences with the radiation sensitizer MTDQ (Sensorad) in advanced malignancies of the head and neck region and in uterine cancer]. (1984)

33 patients with malignancies of the head and neck and 9 patients with carcinoma uteri received Sensorad combined with megavolt-therapy in a placebo controlled trial. 35% of the Sensorad treated patients with head and neck cancer showed an early radiomucositis. A full regression was achieved in 15 patients and a partial regression in 18 patients thus the drug helped in 79% of the patients treated. No regression was noted in 6 patients and a progression in 3, that means in 21% of patients no benefit was detected. In the placebo control group a benefit was proved for 35% of the patients whereas 65% of the patients showed no benefit. The proportion of benefit to no benefit was 3.66 in the Sensorad group compared to 0.54 in the placebo group. The patients with carcinoma uteri all showed a benefit from the treatment with Sensorad. The number of adverse reactions was small. 4 patients had nausea and gastrointestinal symptoms, 2 allergic reactions and 3 elevated SGOT (21.4%).
Engineering of Si-Rich Nitride Charge-Trapping Layer for Highly Reliable Metal–Oxide–Nitride–Oxide–Semiconductor Type NAND Flash Memory with Multi-Level Cell Operation (2012)

The relationship between chemical structure (N/Si ratio) or physical structure (bilayer or laminate structure) of Si-rich nitride charge-trapping layer for metal–oxide–nitride–oxide–semiconductor (MONOS) type NAND flash memory and its electrical characteristics (including program/erase V th window, fresh cell data retention and data retention after program/erase cycling stress) are investigated in detail. A bilayer charge-trapping structure formed by two different composite Si-rich nitride films has been developed that can realize a sufficient program/erase window and excellent data retention characteristics for multi-level cell (MLC) operation.
Detection of an Adherence Factor of Enteropathogenic Escherichia coli with a DNA Probe (1985)

A DNA probe to detect genes conferring localized adherence of enteropathogenic Escherichia coli (EPEC) to Hep-2 cells was evaluated by using E. coli isolates from the stools of Peruvian infants with and without diarrhea. The probe was both sensitive and specific and revealed that Hep-2 adherence (because of the EPEC adherence factor [EAF] was more frequent in some O serogroups of EPEC than in others. Those serogroups in which EAF is almost always found have been designated class I EPEC; serogroups in which EAF is rarely found have been designated class II. Both class I (EAF-positive) and class II EPEC are associated with diarrheal disease.
Dexpanthenol-Nasenspray als wirksames Therapieprinzip zur Behandlung der Rhinitis sicca anterior (1998)

The result of the controlled clinical study confirms that the dexpanthenol nasal spray is an effective medicinal treatment of rhinitis sicca anterior and is more effective than common medications.