gebhart/patrepeval huggingface dataset:
SiGe quantum dots prepared on an ordered mesoporous silica coated Si substrate (1997)

This letter reports a new way of preparing wafer sized SiGe quantum dots on an ordered mesoporous sol gel silica coated Si. It was found from x-ray diffraction that very good regular layers of mesoscopic sized SiGe quantum dots can be formed in the silica. Initial low temperature photoluminescence measurements show much improved light emission of the buried dots. This technique is a potential low cost method for producing quantum dot arrays.
Cationic Lipopolyamines Induce Degradation of PrPSc in Scrapie-Infected Mouse Neuroblastoma Cells (2000)

In prion diseases the endogenous prion protein (PrPC) is converted into an abnormally folded isoform, denoted PrPSc, which represents the major component of infectious scrapie prions. The mechanism of the conversion is largely unknown, but the conversion is thought to occur after PrPC has reached the plasma membrane. Here we show that exogenous administration of the cationic lipopolyamine DOSPA interfered with the accumulation of PrPSc in scrapie-infected neuroblastoma cells. Structural analysis of the compounds tested revealed that inhibition of PrPSc was specific for lipids with a headgroup composed of the polyamine spermine and a quarternary ammonium ion between the headgroup and the lipophilic tail. The cationic lipopolyamine DOSPA induced the cellular degradation of preexisting PrPSc aggregates within 12 hours and interfered with the de novo synthesis of PrPSc. Biosynthesis of PrPC, or the assembly of sphingolipid-cholesterol microdomains (rafts) on the plasma membrane, were not affected by this inhibitor. After removal of DOSPA and replating into normal medium propagation of PrPSc commenced, although initially at a reduced rate. Incubation of ScN2a cells in free spermidine had no inhibitory effect on the accumulation of PrPSc. Our results indicate that membrane targeting of a small polyamine molecule creates a potent inhibitor of PrPSc propagation and offers the possibility to degrade preexisting PrPSc aggregates in living cells.
The Statistical Interpretation of Counting Data from Measurements of Low-level Radioactivity (1977)

The statistical model appropriate to measurements of low-level or background-dominant radioactivity is examined and the derived relationships are applied to two practical problems involving hypothesis testing: “Does the sample exhibit a net activity above background?” and “Is the activity of the sample below some preselected limit?” In each of these cases, the appropriate decision rule is formulated, procedures are developed for estimating the preset count which is necessary to achieve a desired probability of detection, and a specific sequence of operations is provided for the worker in the field.
New implications of 'someone' I. (1966)

New implications of ‘someone’ I. Get access Gilbert Harman Gilbert Harman Princeton University Search for other works by this author on: Oxford Academic Google Scholar Analysis, Volume 26, Issue 6, June 1966, Pages 206–207, https://doi.org/10.1093/analys/26.6.206 Published: 01 June 1966
Self-Powered WSN for Distributed Data Center Monitoring (2016)

Monitoring environmental parameters in data centers is gathering nowadays increasing attention from industry, due to the need of high energy efficiency of cloud services. We present the design and the characterization of an energy neutral embedded wireless system, prototyped to monitor perpetually environmental parameters in servers and racks. It is powered by an energy harvesting module based on Thermoelectric Generators, which converts the heat dissipation from the servers. Starting from the empirical characterization of the energy harvester, we present a power conditioning circuit optimized for the specific application. The whole system has been enhanced with several sensors. An ultra-low-power micro-controller stacked over the energy harvesting provides an efficient power management. Performance have been assessed and compared with the analytical model for validation.
Trusting mobile user devices and security modules (1997)

The market for devices like mobile phones, multifunctional watches, and personal digital assistants is growing rapidly. Most of these mobile user devices need security for their prospective electronic commerce applications. While new technology has simplified many business and personal transactions, it has also opened the door to high-tech crime. We investigate design options for mobile user devices that are used in legally significant applications.
The inverse relationship between reduced folate carrier function and Pemetrexed activity in a human colon cancer cell line (2006)

Pemetrexed, a new generation antifolate recently approved for the treatment of mesothelioma and non-small cell lung cancer, is an excellent substrate for the reduced folate carrier (RFC). To explore the carrier's effect on pemetrexed activity, RFC was inactivated in HCT-15 colon cancer cells by mutagenesis and PT632 selective pressure. A clone (PT1) was obtained with a glycine to arginine substitution at amino acid 401, resulting in the loss of RFC function. PT1 cells were resistant to PT632 (178-fold), methotrexate (4-fold), and ZD1694 (Tomudex, raltitrexed; 20-fold), but were 3-fold collaterally sensitive to pemetrexed when grown in 25 nmol/L of 5-formyltetrahydrofolate. PT1 cells transfected with wild-type RFC had antifolate sensitivities comparable to that of wild-type HCT-15 cells, indicating that the RFC mutation was the sole basis for resistance. Folate pools were contracted in PT1 cells by 32% or 60%, as measured by radiolabeling intracellular folates or by an enzyme binding assay, respectively. This was reflected in marked (6.5-fold) collateral sensitivity to trimetrexate. The initial uptake of pemetrexed in PT1 cells was markedly reduced ( approximately 85%) but intracellular pemetrexed levels increased to approximately 60% and approximately 70% to that of wild-type cells after 2 hours and 6 days, respectively. There was increased pemetrexed inhibition of glycinamide ribonucleotide transformylase and, to a lesser extent, thymidylate synthase in PT1 cells growing in 5-formyltetrahydrofolate based on nucleoside protection analyses. Hence, loss of RFC function leads to collateral sensitivity to pemetrexed in HCT-15 cells, likely due to cellular folate pool contraction resulting in partial preservation of pemetrexed polyglutamylation and increased target enzyme inhibition. micro
On Reducing Mesh Delay for Peer-to-Peer Live Streaming (2008)

Peer-to-peer (P2P) technology has emerged as a promising scalable solution for live streaming to large group. In this paper, we address the design of overlay which achieves low source-to-peer delay, is robust to user churn, accommodates of asymmetric and diverse uplink bandwidth, and continuously improves based on existing user pool. A natural choice is the use of mesh, where each peer is served by multiple parents. Since the peer delay in a mesh depends on its longest path through its parents, we study how to optimize such delay while meeting a certain streaming rate requirement. We first formulate the minimum delay mesh problem and show that it is NP-hard. Then we propose a centralized heuristic based on complete knowledge which serves as our benchmark and optimal solution for all the other schemes under comparison. Our heuristic makes use of the concept of power in network given by the ratio of throughput and delay. By maximizing the network power, our heuristic achieves very low delay. We then propose a simple distributed algorithm where peers select their parents based on the power concept. The algorithm makes continuous improvement on delay until some minimum delay is reached. Simulation results show that our distributed protocol performs close to the centralized one, and substantially outperforms traditional and state-of-the-art approaches.
Multiple-antenna differential lattice decoding (2005)

From a lattice viewpoint, Clarkson, Sweldens and Zheng significantly reduced the complexity of multiantenna differential decoding. Their approximate decoding algorithm, however, has not unleashed the full potential of lattice decoding. In this paper, we present several improved algorithms, generally referred to as differential lattice decoding (DLD), for multiantenna communication. We first analyze two distinct approximate DLD algorithms, and then develop an algorithm that exactly finds the closest lattice point in the Euclidean space. This exact DLD is subsequently augmented by local search to compensate for the remaining approximation. The small amount of extra complexity of the exact or augmented DLD is rewarded by a clear performance gain. We find that employing basis reduction is very effective to reduce the overall decoding complexity for high lattice dimensions. Moreover, the dimension of the lattice defined in this paper is independent of the number of receive antennas, which results in not only lower complexity, but also better performance for a multiantenna receiver.
The Role Played by Serine Proteases in the Development and Worsening of Vascular Complications in Type 1 Diabetes Mellitus (2006)

Much attention has been given to the role played by serine proteases in the development and worsening of vascular complications in Type 1 diabetes mellitus. A generalized increase in proteolytic activity, either due to a true increase in concentration of specific proteases or defects of their protease inhibitors, represents an early marker of diabetes. However, the precise molecular mechanism whereby an unopposed proteolytic activity leads to overt vascular alterations has not fully been elucidated as yet. The picture is further complicated by the fact that, although sharing the same function, serine proteases constitute a structurally heterogeneous class of molecules. Besides classical proteases, for most part belonging to coagulative and fibrinolytic systems, other unrelated molecules exhibit serine-like protease activity and are capable of triggering both inflammatory and immune reactions. The specific role of these non classical serine proteases in the complex pathogenesis of diabetes and its vascular complications is attracting a new investigative interest, as these molecules may represent additional therapeutic targets. This review will focus on most recent acquisitions on this issue relevant to Type 1 diabetes.
Optical add–drop multiplexer based on an asymmetric Bragg coupler (1998)

In this paper, we analyze the performance of a type of optical add–drop multiplexer based on an asymmetric Bragg grating coupler which has recently been proposed [IEEE Photon. Tech. Lett. 8 (1996) 1656]. The purpose of this analysis is both to provide design insight and to determine the feasibility of making such a device based on ultraviolet-induced phase gratings in an asymmetric fiber or channel–waveguide coupler that meets the demanding specifications of current and next-generation wavelength-division multiplexed (WDM) communications systems.
Antibiotic Allergy (2006)

A 55-year-old woman presents to the hospital with cellulitis. She reports a history of urticaria 30 years earlier associated with taking penicillin for a respiratory infection. Should cephalosporins be avoided? More generally, how should patients with a history of antibiotic allergy be evaluated and treated?
A 32-GS/s 6-Bit Double-Sampling DAC in InP HBT Technology (2009)

This paper describes the circuit design and measured performance of a high-speed digital-to-analog converter (DAC) for a coherent optical transceiver based on digital signal processing (DSP). To achieve a high sampling rate, a novel double-sampling technique was devised. A 6-bit DAC test chip was fabricated with InP HBT technology, which yields a peak f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</sub> of 175 GHz and a peak f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</sub> of 260 GHz. Measured DNL and INL were within +0.49/-0.17 LSB and +0.97/-0.06 LSB, respectively. Measured SFDR was 45.0 dB for a sinusoidal output of 72.5 MHz at a sampling rate of 13.5 GS/s, which is the limit of our measurement setup. Ramp-wave output at a sampling rate of 32 GS/s was obtained. Total power consumption was 1.4 W with a supply voltage of -4.0 V. To our knowledge, this is the first 6-bit DAC that can operate at a sampling rate of over 30 GS/s.
Effects of Interferon on Growth Rate and Radiation Sensitivity of Cultured, Human Glioma Cells (1982)

The influence of interferon (IFN) on the growth rate and on the radiation sensitivity of 2 human tumour cell lines was investigated. The 2 glioma cell lines (U-118 MG and U-251 MG) were continuously exposed to IFN (100 U/ml) in the culture medium. Irradiation (3 Gy) was performed either on the first day of IF treatment or on day 14 of IFN treatment. The growth delay induced by the treatments was analysed. The results indicated that IFN had an anti-proliferative effect on the 2 cell lines. However, this effect declined during the treatment and after 2 to 3 weeks of continuous IFN treatment, both cell lines had re-established their original growth rate. IFN did not seem to affect the sensitivity of the cells to radiation. Only an additive effect could be observed.
Pulsatile non-Newtonian blood flow simulation through a bifurcation with an aneurysm (1989)

Blood flow is analysed by means of computer simulation in an idealized arterial bifurcation model which is pathologically altered by a saccular aneurysm. The theoretical study of the flow pattern and the paths of fluid particles is carried out under pulsatile Newtonian and non-Newtonian flow conditions. The governing equations are solved numerically with the use of the finite element method. The results show the disturbed blood flow in the bifurcation and the relatively low intra-aneurysmal flow circulation. In addition to the study of basic flow patterns in the segment, a comparison of non-Newtonian and Newtonian results is carried out. This comparison proves that for the considered large artery model under physiological flow conditions where the yield number is relatively low there is no essential difference in the results.
Xanthoquinodins, new anticoccidial agents produced by Humicola sp. Production, isolation and physico-chemical and biological properties. (1993)

Humicola sp. FO-888, a soil isolate, was found to produce a series of new anticoccidial compounds. Five active compounds, designated xanthoquinodins A1, A2, A3, B1 and B2 were isolated from the fermentation broth of the producing strain by solvent extraction and HPLC. Xanthoquinodins inhibited the growth of Eimeria tenella in an in vitro assay system using BHK-21 cells as a host. No schizont in the cells was observed at concentrations of 0.02-0.2 micrograms/ml for xanthoquinodins A1, A3, B1 and B2 and at 0.02 micrograms/ml for xanthoquinodin A2.
Desertification (2017)

Desertification has generated a great deal of controversy since the term was coined nearly 100 years ago. Strongly informed by a long Anglo‐European history of thinking about desert regions and indigenous people, desertification most commonly conjures images of spreading deserts that threaten lives and livelihoods. This largely colonial notion, however, has been disproved as it has been shown repeatedly that deserts are not inexorably expanding. Moreover, the severity and extent of dryland degradation was significantly exaggerated during the twentieth century. Dryland degradation, particularly from over‐irrigation and increasing dryland agriculture in marginal areas, has occurred but in limited areas for specific reasons. Despite broad scientific and academic consensus that desertification is limited in dryland nonequilibrium environments that are quite resilient, a majority of policy from the local to the international level continues to implement outdated techniques to try to “roll back the desert.”
EXPERIMENTAL RENAL HETEROTRANSPLANTATION (1966)

Renal heterotransplant rejection was studied in the dog and pig, an experimental model representing widely divergent phylogenetic species. Whole organ heterograft rejection in these species was characterized by an immediate reaction (pig to dog 10–20 min and dog to pig 2–4 hours) manifested grossly and histologically by congestion, endothelial destruction and hemorrhage. In this model the mechanism responsible for the immediate vascular rejection process was demonstrated to be preformed cytotoxic antibody. Analysis of complement depression following heterotransplantation suggested the possibility of 2 components of rejection, the first directed against red cell antigens and the second against tissue antigens. The pattern of heterograft rejection was not altered by: (1) differences in blood types of the heterotransplanted animals; (2) qualitative differences in erythrocyte cross-matched results; (3) antibody absorption in vivo; (4) immunosuppressive drugs.
Friction and Wear of Surface-Immobilized C60 Monolayers (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFriction and Wear of Surface-Immobilized C60 MonolayersLorraine M. Lander, William J. Brittain, Vito A. DePalma, and Sharon R. GirolmoCite this: Chem. Mater. 1995, 7, 8, 1437–1439Publication Date (Print):August 1, 1995Publication History Published online1 May 2002Published inissue 1 August 1995https://pubs.acs.org/doi/10.1021/cm00056a005https://doi.org/10.1021/cm00056a005research-articleACS PublicationsRequest reuse permissionsArticle Views151Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Adaptive learning for damage classification in structural health monitoring (2009)

A key challenge in real-world structural health monitoring (SHM) is diversity of damage phenomena and variability in environmental and operational conditions. Conventional learning techniques, while adequate for moderately complex inference tasks, can be limiting in highly complex and rapidly changing environments, especially when insufficient data is available. We present an adaptive learning methodology where stochastic models continuously evolve with the time-varying environment and Dirichlet process mixture models are utilized to self-adapt to structure within the data. Coupled with appropriate physics-based phenomenology, the approach provides an adaptive and effective framework for online SHM. The proposed technique is demonstrated for the detection of progressive fatigue damage in a metallic structure under variable-amplitude loading.
A Review on Different Image Interpolation Techniques for Image Enhancement (2013)

Abstract — Image enhancement is an important processing task in image processing field. By applying image enhancement, blur or any type of noise in the image can be removed so that the resultant image quality is better. Image enhancement is used in various fields like medical diagnosis, remote sensing, agriculture, geology, oceanography. There are numbers of techniques for image enhancement. Image interpolation is used to do enhancement of any image. This paper gives overview about different interpolation techniques like nearest neighbor, bilinear, bicubic, new edge-directed interpolation (NEDI), data dependent triangulation (DDT), and iterative curvature-based interpolation (ICBI).
MicroComputed Tomography: Methodology and Applications (2008)

"MicroComputed tomography has become the gold standard for studying 3D microscopic structures nondestructively, and this book provides up-to-date coverage of the modality. The first part of the book focuses on methodology, covering experimental methods, data analysis, and visualization approaches. Emphasis is on fundamentals so that those new to the field can design their own effective microCT studies. The second part addresses various microCT applications, organized by type of microstructure so that the reader can appreciate approaches from other disciplines. The applications include porous solids, microstructural evolution, soft tissue studies, applications using x-ray phase contrast or x-ray scattering contrast, and multimode studies"--
Identification of Strong Modifications in Cation Selectivity in an Arabidopsis Inward Rectifying Potassium Channel by Mutant Selection in Yeast (1995)

The Arabidopsis thaliana cDNA, KAT1, encodes a hyperpolarization-activated K+ channel. In the present study, we utilized a combination of random site-directed mutagenesis, genetic screening in a potassium uptake-deficient yeast strain, and electrophysiological analysis in Xenopus oocytes to identify strong modifications in cation selectivity of the inward rectifying K+ channel KAT1. Threonine at position 256 was replaced by 11 other amino acid residues. Six of these mutated KAT1 cDNAs complemented a K+ uptake-deficient yeast strain at low concentrations of potassium. Among these, two mutants (T256D and T256G) showed a sensitivity of yeast growth toward high ammonium concentrations and a dramatic increase in current amplitudes of rubidium and ammonium ions relative to K+ by 39-72-fold. These single site mutations gave rise to Rb+- and NH4(+)-selective channels with Rb+ and NH4+ currents that were approximately 10-13-fold greater in amplitude than K+ currents, whereas the NH4+ to K+ current amplitude ratio of wild type KAT1 was 0.28. This strong conversion in cation specificity without loss of general selectivity exceeds those reported for other mutations in the pore domain of voltage-dependent K+ channels. Yeast growth was greatly impaired by sodium in two other mutants at this site (T256E and T256Q), which were blocked by millimolar sodium (K1/2 = 1.1 mM for T256E), although the wild type channel was not blocked by 110 mM sodium. Interestingly, the ability of yeast to grow in the presence of toxic cations correlated to biophysical properties of KAT1 mutants, illustrating the potential for qualitative K+ channel mutant selection in yeast. These data suggest that the size of the side chain of the amino acid at position 256 in KAT1 is important for enabling cation permeation and that this site plays a crucial role in determining the cation selectivity of hyperpolarization-activated potassium channels.