gebhart/patrepeval huggingface dataset:
Dual mode coupling by square corner cut in resonators and filters (1992)

A method for realization of dual-mode coupling in rectangular waveguide cavities is described and analyzed. The method completely replaces the coupling screw, and therefore can be used to eliminate the need for tuning in dual-mode waveguide cavity filters. It also offers a wide range of coupling values and can achieve higher power-handling capability than coupling screws. Mode matching is used to calculate the mode chart of the infinitely long square corner cut rectangular waveguide (SCCRW), the field distributions of each mode, and the resonant frequencies of the cavity. An evanescent mode rectangular waveguide is used to provide dual-mode couplings between adjacent cavities. The junction discontinuity between the SCCRW and the rectangular waveguide is modeled by a double mode-matching method, yielding modal scattering parameters of the junction. A four-pole dual-mode elliptic-function rectangular waveguide cavity filter using the coupling method was constructed. The experimental filter results showed excellent agreement with theory.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress (2006)

Lowered shear stress and oscillatory shear stress are both essential conditions in plaque formation. Lowered shear stress induces larger lesions with a vulnerable plaque phenotype, whereas vortices with oscillatory shear stress induce stable lesions.
Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue. (2006)

Downregulation in cultured HTM cells of genes potentially relevant for outflow pathway function highlights the importance of developing new conditions for the culture of TM cells capable of preserving the characteristics of TM cells in vivo. Comparative analysis between control and POAG tissues suggests that the upregulation of inflammation-associated genes might be involved in the progression of glaucoma.
Figure of merit for low frequency anechoic chambers based on absorber reflection coefficients (1996)

Return loss as a function of frequency and angle of incidence is studied to determine the effectiveness of the absorbing material used in an anechoic chamber. This alone is not enough to determine a figure of merit for an anechoic chamber or to compare the figure of merit for one anechoic chamber to that of another. While the information gained from return loss calculations and measurements as a function of angle of incidence is valuable, an overall measure of anechoic chamber effectiveness is necessary in order to compare different designs. In this paper, a new chamber figure of merit which is based on the decay time of the chamber is introduced. This decay time is, in turn, based on the average power absorbed by the chamber walls. The resulting model is simple and does not require intensive numerical computation. Calculations of the figure of merit for anechoic chambers which contain different types of absorbing materials are shown, and calculated and measured values of decay time for a primary standards calibrations facility are compared.
Effectiveness of using supply voltage as back-gate bias in ground plane SOI MOSFET (2005)

We show that GP-SOI MOSFETs are optimal for the DBB scheme offering high on-current and low design complexity without having power performance issues related to the forward-biased p-n junction current in bulk CMOS. It is also shown that GP-SOI can deliver the same performance as DG-SOI 90X lower standby leakage by dynamically switching the back-gate bias.
Computer‐Aided Design in Protein Engineering (1987)

SCOPUS: ar.j
Self‐Replenishing Surfaces (2012)

Damaged surfaces self-replenish their chemical composition by the spontaneous re-orientation of functional groups chemically bonded to the polymer network. The repair of the surface chemistry leads to the recovery of surface functionality. This self-replenishing approach is suitable to recover many surface-related properties and constitutes a major breakthrough in extending the service life-time of functional materials.
Effects of tumor promoters on growth and on cellular redistribution of phospholipid/CA<sup>2+</sup>‐dependent protein kinase in human breast cancer cells (1986)

Active, structurally unrelated tumor promoters (12-0-tetradecanoyl-phorbol-13-acetate (TPA), teleocidin and aplysiatoxin) inhibit growth of mammary carcinoma cells (MCF7- greater than BT-20 greater than MDA-MB-231 greater than = ZR-75-1 greater than HBL-100). This efficiency in inhibiting cell growth correlates with the tumor-promoting activity of a series of phorbol ester derivatives. The phospholipid/calcium-dependent protein kinase (PKC), a target for phorbol ester action, was measured by polyacrylamide gel electrophoresis. The levels of PKC were higher (p less than 0.001) in estrogen-receptor-negative than in estrogen-receptor-positive cells. Treatment of cells with active tumor promoters results in time- and dose-dependent translocation of cytosolic PKC to membrane fractions. Less potent phorbol esters induce only partial translocation of PKC (i.e., decrease of cytosolic without increase in membrane-bound PKC), whereas inactive esters have no effect. No correlation was found between PKC concentration or the amount of PKC translocated to membranes and the sensitivity of the respective cells to TPA. It is concluded that tumor-promoter-mediated growth inhibition of breast cancer cell lines is due to mechanism(s) occurring after the translocation of PKC.
ATM virtual path self-healing based an a new path restoration protocol (2002)

Many studies have many studies have been conducted using ATM technology to implement B-ISDN. These have shown that ATM virtual path (VP) technology, due to its fast cross-connect system, can be used to achieve rapid restoration for a distributed control mesh-type restoration system. The signaling channel using operations and maintenance (OAM) cells further improves restoration time because of the high bandwidth available to the OAM cells in an ATM VP network. Within the framework of logical channel protection scheme, self-healing restoration can be provided at two different schemes: path restoration and line restoration. Path restoration restores the end to end logical channel (i.e. finds an alternative logical channel), and line restoration restores demands carried by the failed link. We propose a new three-phase distributed VP self-healing scheme using path restoration protocol to achieve high restoration ratio, with an average restoration time of around 1-second, and less spare capacity assignments due to more efficient usage of them in the network. An empirical study based on a real metropolitan LATA mesh network shows that, under the condition of assigning sufficient VPs between the same source and destination, the three-phase path restoration protocol has superior performance compare to the existing two-phase line restoration protocol over a number of networks with randomly generated VP assignments and spare capacity assignments. This empirical study also shows that restoration times of the proposed path restoration protocol are mostly around 1 second which is well suited for metropolitan LATA mesh networks.
Noise figure optimization of inductively degenerated CMOS LNAs with integrated gate inductors (2006)

This paper discusses noise figure optimization techniques for inductively degenerated cascode CMOS low-noise amplifiers (LNAs) with on-chip gate inductors. Seven different optimizations techniques are discussed. Of these, five new cases provide power match and balance the transistor noise contribution and the noise contribution from all parasitic resistances in the gate circuit to achieve the best noise performance under the constraints of integrated gate inductor quality factor, power consumption, and gain. Three of the power matched techniques (two power constrained optimizations and a gain-and-power constrained optimization) are recommended as design strategies. These three optimization techniques significantly improve the noise figures for LNA designs that are to employ on-chip gate inductors.
Electrical conductivity of sweat: a simple, home-assembled apparatus. (1963)

An apparatus for determining the electrical conductivity of undiluted sweat has been described. The technique used and the results obtained have been presented. The results indicate that the instrument, when used with the technique described, is of value in the diagnosis of cystic fibrosis in children.
Membrane‐Mimetic Nanocarriers Formed by a Dipalmitoylated Cell‐Penetrating Peptide (2005)

Detergent activity is conferred upon a cell-penetrating peptide by dipalmitoylation, and the peptide can incorporate large amounts of phospholipid into supramolecular particles with unique physicochemical properties. These nanocarriers combine the advantages of both liposomes and micelles as they offer a membrane-like environment in spite of their small size, thus preserving the biofunctionality of the vector peptide and affording efficient internalization into live cells. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z500519_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Clinical Efforts to Combine Endocrine Agents with Targeted Therapies against Epidermal Growth Factor Receptor/Human Epidermal Growth Factor Receptor 2 and Mammalian Target of Rapamycin in Breast Cancer (2006)

Enhancing the benefit of endocrine therapy by overcoming de novo or acquired resistance remains an important goal in systemic breast cancer therapy. Progress continues to be made in elucidating the molecular pathways by which estrogen receptor-positive breast cancer cells escape from endocrine therapy. The increasing recognition of the roles of epidermal growth factor receptor (EGFR) and human EGFR2 in cross-talk activation of estrogen receptor signaling has led to studies aimed at identifying whether small-molecule tyrosine kinase inhibitors targeted against these receptors give additive or synergistic effects when combined with endocrine agents. Activation of the phosphatidylinositol-3-OH kinase/Akt pathway has also been associated with resistance to either tamoxifen or estrogen deprivation, and preclinical studies have shown that the mammalian target of rapamycin antagonist temsirolimus can restore endocrine sensitivity in breast cancer cells. Randomized phase II trials of aromatase inhibitors combined with EGFR/human EGFR2 tyrosine kinase inhibitors or mammalian target of rapamycin antagonists have been completed in both the neoadjuvant and advanced breast cancer settings. Larger phase III trials with both approaches are now in progress and have been powered to detect whether either strategy can significantly prolong time to disease progression compared with endocrine therapy alone. The correlation of molecular and clinical results from these ongoing studies will be important to establish appropriate biological variables for selecting those patients who may benefit most from this combined approach.
Multiple Agent Autonomous Control A Hybrid Systems Architecture (1993)

Hybrid systems are systems in which a digital control automaton receives sampled sense data about the state of a continuous plant and, occasionally, issues a change in the control law for a plant controller. The digital control automaton may fail to meet design requirements for local control of plant state trajectory, and need to be replaced on-line. This paper is an overview of our architecture for systems in which there is a plant (or system of plants called plant processes), each plant process has a plant controller with an Agent for its digital control program and plant process controller. That Agent monitors its plant process and its plant process controller and its digital control program, passes and receives messages to and from other Agents for other plant processes, and occasionally computes and installs a new finite digital control automaton for its plant process controller. There is no supervisor. We call this Multiple Agent Hybrid Control. It is to be emphasized that the purpose of the Agent is to construct new finite control automata to replace old ones on the fly whenever performance and controllability and observability criteria are violated, and that the Agents have no central supervisor. The tools used are distributed message passing from Agent to Agent of information about Lagrangians, and the Lagrangian variational-automata method for extracting the digital control automata of Kohn’s declarative control [20]. The underlying hybrid systems model is that of Kohn-Nerode [34].
Politicised compassion and pedagogical partnership: A discourse and practice for social justice in the inclusive academy (2020)

Despite changes prompted by global legalisation and policy developments for social justice and inclusion, many institutions of higher education remain driven by neoliberal values, an endemic culture of performativity, and an emphasis on individual success. These phenomena inform, disfigure, and invert inclusion and equality in policy, practice, and outcome. In response, we propose politicised compassion fostered through pedagogical partnership as a political and social justice reaction to the status quo. This paper explores this proposal, grounding it in international research studies on student experience, partnership, and equality. The work’s novelty is in its advancement of Zembylas’ (2013) work on “critical compassion” through what we term politicised compassion with the goal of enabling sustained student agency, student success, and the creation of active, considerate citizens. Our work invites critical considerations of where such a discourse for meaningful social justice and equality can take place within the academy.
Catalyst Screening for the Production of Furfural from Corncob Pyrolysis (2012)

Acidic pyrolysis of corncobs is carried out at 800 K in a packed-bed reactor using several catalysts (H2SO4, H3PO4, H3BO3, (NH4)2SO4, ZnCl2, NiCl2, MgCl2, and Fe2(SO4)3). In all cases, the yields of char, water, and some condensable organic compounds (acetic acid, levoglucosenone, 1,4:3,6-dyanhydro-α-d-glucopyranose, and furfural) are significantly increased at the expense of the phenolic and carbohydrate products typical of uncatalyzed pyrolysis. The maximum yields of furfural (FF) are around 5–6% for the H2SO4, Fe2(SO4)3 ,and ZnCl2 treatments, with potential further increase, following secondary degradation of the main anhydrosugars, up to 8.5% (H2SO4, Fe2(SO4)3) or 6.5% (ZnCl2). Additional experiments made with a wide range of Fe2(SO4)3 concentrations, and a comparison with previous results obtained for H2SO4 and ZnCl2 treatments indicate that the best performances are shown by the first catalyst with potential FF yields up to 10%. Moreover, at low concentrations, it also highly promotes the formation of levoglucosan, 5-methylfurfural, 5-hydroxymethylfurfural, 4-hydroxy-5,6-dihydro-(2H)-pyran-2-one, and 3-hydroxy-2-penteno-1,5-lactone, 1-hydroxy-3,6-dioxabicyclo[3.2.1]octan-2-one.
Effect of chain length on coiled‐coil stability: Decreasing stability with increasing chain length (2004)

The de novo design and biophysical characterization of three series of two-stranded alpha-helical coiled coils with different chain lengths are described. Our goal was to examine how increasing chain length would affect protein folding and stability when one or more heptad repeat(s) of K-A-E-A-L-E-G (gabcdef) was inserted into the central region of different coiled-coil host proteins. This heptad was designed to maintain the continuous 3-4 hydrophobic repeat of the coiled-coil host and introduce an Ala and Leu residue in the hydrophobic core at the a and d position, respectively, and a pair of stabilizing interchain ionic i to i' + 5 (g to e') interactions per heptad inserted. The secondary structures of the three series of disulfide-bridged polypeptides were studied by CD spectroscopy and their stabilities determined by chemical and thermal denaturation. The results showed that successive insertions of this heptad systematically decreased the stability of all the coiled coils studied regardless of the overall initial stability of the host coiled coil. These observations are in contrast to the generally accepted implication that the folding and stability of coiled coils are enhanced with increasing chain length. Our results imply that, in these examples where an Ala and Leu hydrophobic residue were introduced into the coiled-coil core per inserted heptad, there was still insufficient stability to overcome unfavorable entropy associated with chain length extension, even though the inserted heptad contained the most stabilizing hydrophobic residue (Leu) at position d and stabilizing ionic attractions.
A Novel Subunit of Vacuolar H+-ATPase Related to The <i>b</i> Subunit of F-ATPases (1996)

The subunit structure of the vacuolar H(+)-ATPase (V-ATPase) membrane sector is not entirely known. The proteolipid is the only subunit that has been implicated in the mechanism of energy transfer in the enzyme. We have identified a protein (M16) that co-purifies with the V-ATPase complex from bovine chromaffin granules. Information obtained from the amino acid sequence of a proteolytic fragment of M16 was used to clone a bovine adrenal cDNA encoding this protein. The cDNA encodes a hydrophilic protein of 118 amino acid residues with a calculated molecular mass of 13682Da. Amino acid sequence analysis revealed that M16 exhibits a significant homology to subunit b of F-ATPases. M16 is smaller than subunit b and contains no apparent transmembrane segment in its N terminus. The remainder of subunit b is related to M16 not only by its amino acid sequence but also in its predicted structure of helix-turn-helix. The structural and evolutionary implications of these findings are discussed.
Chemical Reactivity of Triphenyl Phosphorothionate (TPPT) with Iron: An ATR/FT-IR and XPS Investigation (2010)

The surface reactivity of triphenyl phosphorothionate (TPPT) on air-oxidized iron surfaces has been studied by in situ attenuated total reflection Fourier transform infrared spectroscopy (ATR/FT-IR) and ex situ X-ray photoelectron spectroscopy (XPS). The ATR/FT-IR spectra indicate that a reaction took place at 423 K on the iron-coated germanium ATR crystal with the formation of pyrophosphates, organophosphates, and sulfates. The oxidation of the base oil (poly-α-olefin, PAO) during thermal testing, leading to the production of oxygenated compounds that can adsorb onto the iron surface and react with it, resulted in the presence of carbonates and carboxylates in the film. As the heating time increased, the corrosion of the iron coating by the aggressive species formed during the thermooxidative aging of PAO provided the cations necessary for the formation of orthophosphate compounds. The subsequent ex situ XPS analysis, besides substantiating the formation of short-chain polyphosphates, organophosphates, and sulfates on the air-oxidized iron surface, indicates the presence of oxygenated organic compounds in the outermost part of the reaction layer. Modeling the ATR/FT-IR system allowed the correlation of the changes observed in the experimental ATR/FT-IR spectra with the reflectivity alterations caused by the formation of reaction products on the iron-coated germanium ATR crystal. On the basis of these findings, a mechanism for the reaction of TPPT at the oil/iron oxide interface has been proposed.
Genetical Studies on the Mode of Inheritance and Localization of the <i>amo1</i> (High Amylose) Gene in Barley (1992)

Abstract In the high amylose starch mutant ‘Glacier AC38’, a single recessive gene designated amo1 is responsible for an amylose content of up to 45%. A rapid technique was established in order to evaluate the amylose/amylopectin ratio in half kernels. To localize this gene, crosses with multiple marker lines and trisormes were conducted. In addition, RFLP markers were used to determine their mapping distance to amo1 . Two markers are located 2 cM and 7 cM, respectively, from amo1 on chromosome 5S (1HS). The relationship between the wx and amo1 genes was also examined and the role of the amo1 gene in starch synthesis is discussed.
Organic Rankine Cycle Configurations (2007)

In the last two decades the binary power plant, utilizing the Organic Rankine Cycle (ORC), has become a preferred means of exploiting low to moderate enthalpy geothermal resources. It has been widely used to utilize the brine in existing single flash plants and in many other applications as an efficient and reliable way of employing a geothermal resource, in the form of brine only or brine and low pressure steam coming from a separator. Over the years the basic ORC has been improved and modified to better adapt the cycle to various conditions of the heat source. In this paper we will describe some advanced versions of the Organic Rankine Cycle and will demonstrate its means of providing an efficient conversion cycle adapted to specific thermal and chemical properties of geothermal fluid sources.
Absorption of blood by moist wound healing dressings (2003)

An understanding of the various properties of the many dressings on the market enables the clinician to select the appropriate dressing product for the patient’s wound. A comparative analysis of the ability of moist wound healing (MWH) products to absorb blood has not been previously reported. The aim of this study was to compare the rate and the maximal weight of blood absorbed, the ability of the dressings to retain blood within the dressing when under pressure, sheet integrity, and lateral wicking of the blood within the dressing. The MWH dressings tested included 12 ‘fibre’ dressings (alginates and hydrofibre) and 15 ‘absorptive’ (polyurethrane foams, hydroactive and combination products). The most absorbent fibre dressings were Hydroheal Algin Firm, Sorbalgon, Cutinova Alginate, Kaltostat and Restore Calcicare, absorbing greater than 35g of blood per 100cm 2 dressing. The least absorbent was Aquacel with 21.5g/100cm 2 . The integrity of the fibre dressings varied markedly from Sorbsan, which disintegrated, to Curasorb and Seasorb Alginates, which retained full strength. The rate of absorption of all fibre dressings was rapid (<18 seconds). Lateral wicking was least with Aquacel and greatest with Algoderm and Kaltostat. The absorptive dressings showed a wide variation in absorptive capacity, from Flexipore which absorbed only 1.7g/100cm 2 to Allevyn which absorbed 79.9g/100cm 2 and Hydrasorb 79.4 g/100cm 2 . Under pressure, Cutinova Foam retained the greatest amount of blood. Rate of absorption varied dramatically between products, with Polymem Alginate, Polymem, Exu-dry, Biatain and Hydrasorb all taking less than 1 minute to absorb 1ml of blood, whilst seven dressings showed incomplete absorption after