gebhart/patrepeval huggingface dataset:
Anodic oxidation of carboxamides. Part 3. The mechanism of anodic cyclization of N-methylcarbanilides (1981)

Anodic oxidation in methanol of N-methylcarbanilides with an alkoxy-group para to the nitrogen atom (I) gives the intramolecular cyclization products, N-methylbenzoxazolium perchlorates: no cyclization product is obtained in the electrolysis of the anilides in acetonitrile. The process of cyclization was investigated by cyclic voltammetry, controlled potential electrolysis, and open circuit relaxation experiments using an optically transparent glassy carbon electrode. In spectroelectrochemical experiments on 4′-methoxy-N-methylbenzanilides (Ib–d) in methanol, accumulation of a metastable intermediate has been demonstrated. A possible reaction sequence for the formation of the benzoxazolium salts is discussed.
The <i>comP</i> locus of <i>Neisseria gonorrhoeae</i> encodes a type IV prepilin that is dispensable for pilus biogenesis but essential for natural transformation (1999)

The expression of type IV pili (Tfp) by Neisseria gonorrhoeae has been shown to be essential for natural genetic transformation at the level of sequence-specific uptake of DNA. All previously characterized mutants defective in this step of transformation either lack Tfp or are altered in the expression of Tfp-associated properties, such as twitching motility, autoagglutination and the ability to bind to human epithelial cells. To examine the basis for this relationship, we identified potential genes encoding polypeptides sharing structural similarities to PilE, the Tfp subunit, within the N. gonorrhoeae genome sequence database. We found that disruption of one such gene, designated comP (for competence-associated prepilin), leads to a severe defect in the capacity to take up DNA in a sequence-specific manner, but does not alter Tfp biogenesis or expression of the Tfp-associated properties of auto-agglutination, twitching motility and human epithelial cell adherence. Indirect evidence based on immunodetection suggests that ComP is expressed at very low levels relative to that of PilE. The process of DNA uptake in gonococci, therefore, is now known to require the expression of at least three distinct components: Tfp, the recently identified PilT protein and ComP.
A Hebrew Folksong (1914)

Research Article| June 01 1914 A Hebrew Folksong John P. Peters John P. Peters Search for other works by this author on: This Site Google Journal of Biblical Literature (1914) 33 (2): 158–159. https://doi.org/10.2307/3259972 Cite Icon Cite Share Icon Share Twitter Permissions Search Site Citation John P. Peters; A Hebrew Folksong. Journal of Biblical Literature 1 June 1914; 33 (2): 158–159. doi: https://doi.org/10.2307/3259972 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveSBL PressJournal of Biblical Literature Search Advanced Search The text of this article is only available as a PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Detecting the Staff-Lines of Musical Score with Hough Transform and Mathematical Morphology (2010)

This paper presents conventional architecture of Optical Music Recognition (OMR), staff-lines detection is a key stage in OMR. It explains two major methods of staff-lines detection in detail, and it selects 68 images to experiment for the methods. The result of experiment indicates that two methods both can detect all staff-lines of an image by Hough Transform and Mathematical Morphology, but the runtime of Hough Transform is long than Mathematical Morphology.
Dose–response plasma appearance of coffee chlorogenic and phenolic acids in adults (2013)

This study confirmed previous findings about coffee bioavailability but also showed that coffee phenolics appear in a positive dose-response manner in plasma when drank at nutritionally relevant doses.
Interactive Visual Analysis of Perfusion Data (2007)

Perfusion data are dynamic medical image data which characterize the regional blood flow in human tissue. These data bear a great potential in medical diagnosis, since diseases can be better distinguished and detected at an earlier stage compared to static image data. The wide-spread use of perfusion data is hampered by the lack of efficient evaluation methods. For each voxel, a time-intensity curve characterizes the enhancement of a contrast agent. Parameters derived from these curves characterize the perfusion and have to be integrated for diagnosis. The diagnostic evaluation of this multi-field data is challenging and time-consuming due to its complexity. For the visual analysis of such datasets, feature-based approaches allow to reduce the amount of data and direct the user to suspicious areas. We present an interactive visual analysis approach for the evaluation of perfusion data. For this purpose, we integrate statistical methods and interactive feature specification. Correlation analysis and Principal Component Analysis (PCA) are applied for dimensionreduction and to achieve a better understanding of the inter-parameter relations. Multiple, linked views facilitate the definition of features by brushing multiple dimensions. The specification result is linked to all views establishing a focus+context style of visualization in 3D. We discuss our approach with respect to clinical datasets from the three major application areas: ischemic stroke diagnosis, breast tumor diagnosis, as well as the diagnosis of the coronary heart disease (CHD). It turns out that the significance of perfusion parameters strongly depends on the individual patient, scanning parameters, and data pre-processing.
Robotics research : the First International Symposium (1984)

The fifty-three contributions collected in this book present leading current research in one of fastest moving fields of artificial intelligence. Organized around a view of robotics as the intelligent connection of perception to they convey excitement of cross-disciplinary discussion by scholars from United States, Japan, France, United Kingdom, West Germany, and Australia.Chapters in book's first part explore connection between perception and action in three sections that deal with task level programming, integrated systems, and walking machines. The second part reports recent progress on perceptual basis of robotics, with chapters grouped in sections on visual inspection, three-dimensional vision, and (nonvisual) local sensing. The third part focuses on systems that facilitate action, with sections that discuss mechanisms, kinematics and dynamics, and feedback control. A final part considers application of robot systems to manufacturing, with chapters divided into two sections: on systems for manufacture and on robots and manufacture. The editors have written introductions to each of book's four major parts and eleven sections.This book is twelfth in The MIT Press Series in Artificial intelligence, edited by Patrick Henry Winston and Michael Brady.
Global and efficient self-similarity for object classification and detection (2010)

Self-similarity is an attractive image property which has recently found its way into object recognition in the form of local self-similarity descriptors. In this paper we explore global self-similarity (GSS) and its advantages over local self-similarity (LSS). We make three contributions: (a) we propose computationally efficient algorithms to extract GSS descriptors for classification. These capture the spatial arrangements of self-similarities within the entire image; (b) we show how to use these descriptors efficiently for detection in a sliding-window framework and in a branch-and-bound framework; (c) we experimentally demonstrate on Pascal VOC 2007 and on ETHZ Shape Classes that GSS outperforms LSS for both classification and detection, and that GSS descriptors are complementary to conventional descriptors such as gradients or color.
Healing property of the<i>Piper</i>betel phenol, allylpyrocatechol against indomethacin-induced stomach ulceration and mechanism of action (2007)

APC can protect indomethacin-induced gastric ulceration due to its antioxidative and mucin protecting properties.
A Biquadratic Cell Based on the Flipped-Source-Follower Circuit (2016)

This brief presents a novel biquadratic cell (biquad) based on the flipped-source-follower (FSF) circuit. The main idea is to exploit the FSF circuit as a basic building block for a low-pass second-order filter, taking advantage of its well-known strengths, like low-output impedance, low-noise, large in-band linearity, and low power. Thanks to the very essential FSF circuit, the resulting biquad is a power-efficient broad bandwidth stage, with very low-noise performance. In order to validate the biquad design idea, extensive circuital simulation results will be presented. The filter design example synthesizes a third-order low-pass transfer function and consumes 2.3 mW from a single 1.8 V@V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> . Input noise spectral density is 7 nV/vHz. Linearity has been evaluated in terms of IIP3 (25 dBm) and THD (-40 dBc at 380mV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0-PEAK</sub> output voltage swing, resulting in 62-dB SNR). Hence, a very promising figure-of-merit (i.e., 165 J <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> ) has been achieved.
The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes (1993)

Rat thymocytes have been used to characterize the changes in energy metabolism that occur as cells undergo a resting/proliferation transition. In the resting state, anaerobic ATP production accounts for only 4% of ATP turnover. The remainder is fueled by the oxidation of a mixture of an unidentified endogenous fuel (62%), glucose (18%) and glutamine (16%). 48 h after mitogen stimulation, the ATP turnover has increased twofold. In these proliferating cells, glucose inhibits oxygen consumption by 58%, indicating a profound Crabtree effect which is not present in resting cells. Consequently, proliferating cells, in the presence of glucose and glutamine, fuel the majority (61%) of ATP turnover anaerobically, producing lactate from glucose. The development of a Crabtree effect may be the result of the 8-10-fold increase in glycolytic enzyme activities which occurs with proliferation. Possible advantages of such a proliferative metabolism are a sparing of endogenous fuel, and a minimizing of oxidative metabolism, with its concurrent production of free radicals.
Sputum colour: a useful clinical tool in non-cystic fibrosis bronchiectasis (2009)

This study explored the utility of sputum colour in clinically stable patients with bronchiectasis. Interpretation of sputum colour between the doctor and the patient was reliable (intraclass correlation coefficient 0.83 (95% confidence interval 0.76-0.89). Sputum colour predicted bacterial colonisation (5% in mucoid sputum; 43.5% in mucopurulent sputum; 86.4% in purulent sputum; p<0.0001). On multivariate logistic regression analysis, independent factors associated with purulent sputum were bacterial colonisation, varicose or cystic bronchiectasis, forced expiratory volume in 1 s <80% predicted and diagnosis of bronchiectasis aged <45 yrs.
<p>An Evaluation of a Nutraceutical with Berberine, Curcumin, Inositol, Banaba and Chromium Picolinate in Patients with Fasting Dysglycemia</p> (2020)

A nutraceutical containing Berberine, Curcumin, Inositol, Banaba, and Chromium Picolinate can be helpful in improving glyco-metabolic compensation, TC and Tg value, and in reducing inflammatory status in patients with dysglycemia.
An Improved Synthesis of β-Alanine. III. The Addition of Ammonia to Acrylonitrile at 50-150°<sup>1</sup> (1947)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn Improved Synthesis of β-Alanine. III. The Addition of Ammonia to Acrylonitrile at 50-150°1Jared H. Ford, Saul R. Buc, and J. Ward GreinerCite this: J. Am. Chem. Soc. 1947, 69, 4, 844–846Publication Date (Print):April 1, 1947Publication History Published online1 May 2002Published inissue 1 April 1947https://pubs.acs.org/doi/10.1021/ja01196a029https://doi.org/10.1021/ja01196a029research-articleACS PublicationsRequest reuse permissionsArticle Views156Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes (2010)

Recent studies indicate that csMUC16 can act as an anti-adhesive agent that blocks tumor-immune cell interactions. Our results demonstrate that similar to other mucins, csMUC16 can also facilitate cell adhesion by interacting with a suitable binding partner such as mesothelin or Siglec-9. Siglec-9 is an inhibitory receptor that attenuates T cell and NK cell function. sMUC16/csMUC16-Siglec-9 binding likely mediates inhibition of anti-tumor immune responses.
Adaptive order selection with aid of genetic algorithm (1999)

A method to estimate a nonstationary power spectrum with adaptive selection of autoregressive order is proposed. Time-varying PARCOR (partial autocorrelation coefficient) and AR (autoregressive) order are estimated from time series data. The data are assumed to be observations of vibration that contain abrupt change of spectrum due to arrivals of different signal, structural changes of vibrating object, etc. The model that consists of an autoregressive model with time-varying PARCORs and time-varying order is used. The time-varying PARCORs are estimated by a Monte Carlo filter, and the time-varying order is estimated by genetic algorithm. An application to analysis of seismic wave data is reported.
Nitride-based lasers: advances in cavity design (2000)

Unique constraints encountered in the III-N semiconductor system, such as a lack of cleaving planes and resistance to wet etchants, make conventional approaches to the fabrication of laser diodes difficult to implement, and result in the need for novel cavity designs. Improvements in in-plane cavities include etching facets using a focused ion beam and the incorporation of gratings to decrease losses associated with poor mirrors. Towards the fabrication of an electrically pumped VCSEL, the issue of the bottom mirror can be addressed by the use of dielectric mirrors, and either the removal of the sapphire substrate or its incorporation into the cavity by using a curved backside mirror. This paper will review recent developments in these areas at UC Santa Barbara.
Wideband Infrared Emission from Yb<sup>3+</sup>- and Nd<sup>3+</sup>-Doped Bi<sub>2</sub>O<sub>3</sub>–B<sub>2</sub>O<sub>3</sub> Glass Phosphor for an Optical Coherence Tomography Light Source (2008)

We have investigated the spectroscopic properties of Bi2O3–B2O3 glasses doped with Nd3+ and Yb3+ separately, and doubly doped with the same ions, in order to search for appropriate phosphors for an optical coherence tomography (OCT) light source. The effects of Yb3+ and Nd3+ co-doping and varying Yb3+ concentration on the spectrum shape were studied to obtain an optimum line shape for OCT. We successfully obtained a Gaussian-like shape spectrum from 5.0Yb2O3–1.0Nd2O3–46.0Bi2O3–46.0B2O3 (in nominal molar composition) with a full-width-at-half-maximum (FWHM) of 101 nm in the wavelength region around 1000 nm. This FWHM corresponds to a depth resolution of 4.5 µm, which is about twice that of conventional light emitting diodes (LEDs) and super luminescent diodes (SLDs). The Gaussian-like line shape is very important to suppress ghost images in OCT. These results indicate that a Yb3+, Nd3+ co-doped Bi2O3–B2O3 glass phosphor can indeed be applied as a new type of OCT light source.
Polyphosphate Inhibition of Growth of Plaques Formed by Streptococci and Diphtheroids Implicated in Oral Disease (1970)

Growth of intact bacterial plaques associated with dental caries and peridontal disease is inhibited by some polyphosphates.
Human Induced Pluripotent Stem Cells: The Past, Present, and Future (2011)

A major breakthrough in the past 5 years is the development of the ability to reprogram somatic cells to pluripotency. It has rejuvenated the field of stem cell research, providing regenerative medicine with new possibilities. In this paper, we discuss the progress made in the reprogramming field with focus on induction methodologies, the use of induced pluripotent stem cells (iPSCs) for drug discovery, and issues and precautions related to their use in regenerative medicine. Clinical Pharmacology & Therapeutics (2011) 89 5, 741–745. doi:10.1038/clpt.2011.37
EVALUATION OF SUPERPAVE GYRATORY COMPACTOR IN THE FIELD MANAGEMENT OF ASPHALT MIXES: FOUR SIMULATION STUDIES (1995)

The SHRP-SUPERPAVE Design System utilizes the SUPERPAVE Gyratory Compactor (SGC) for asphalt-mixture specimen compaction. As part of the Demonstration Project Program, the Federal Highway Administration Office of Technology Applications (FHWA-OTA) has incorporated the SGC into FHWA-OTA mobile asphalt laboratories. Simulation studies are conducted for states to demonstrate aspects of the SUPERPAVE Design System, along with the application of certain innovative concepts in field management of asphalt mixes. The use of the SGC for field management is investigated. Four production mixes are evaluated. Based on production results, tolerance limits are established for SGC acceptance parameters. FHWA-OTA-recommended SGC volumetric acceptance parameters are asphalt binder content, voids in total mix, and voids in mineral aggregate. During the studies, companion samples were taken using the standard Marshall compactor. Results indicate that the Marshall compactor cannot be used as a surrogate for the SGC. The two compaction methods do not produce equivalent specimens.
Effect of transient chemically induced colitis on the visceromotor response to mechanical colorectal distension (2002)

Following an acute colitis due to single colorectal instillation of TNB/ethanol, histological changes are associated with an enhanced nociceptive response to CRD.
EMD-Based Symbolic Dynamic Analysis for the Recognition of Human and Nonhuman Pyroelectric Infrared Signals (2016)

In this paper, we propose an effective human and nonhuman pyroelectric infrared (PIR) signal recognition method to reduce PIR detector false alarms. First, using the mathematical model of the PIR detector, we analyze the physical characteristics of the human and nonhuman PIR signals; second, based on the analysis results, we propose an empirical mode decomposition (EMD)-based symbolic dynamic analysis method for the recognition of human and nonhuman PIR signals. In the proposed method, first, we extract the detailed features of a PIR signal into five symbol sequences using an EMD-based symbolization method, then, we generate five feature descriptors for each PIR signal through constructing five probabilistic finite state automata with the symbol sequences. Finally, we use a weighted voting classification strategy to classify the PIR signals with their feature descriptors. Comparative experiments show that the proposed method can effectively classify the human and nonhuman PIR signals and reduce PIR detector's false alarms.
A Combined Approach for Gene Discovery Identifies Insulin-Like Growth Factor-Binding Protein-Related Protein 1 as a New Gene Implicated in Human Endometrial Receptivity (2003)

In the past, human endometrial receptivity has been investigated by chasing specific molecules throughout the menstrual cycle. Now the genomic approach allows us to investigate the hierarchical contribution of a high number of genes to a specific function. In this study, we analyzed differentially the gene expression pattern of 375 human cytokines, chemokines, and related factors, plus that of their receptors, in endometrial receptivity. To do this, we used a combined approach of human endometrium and cell lines. We have compared the gene expression pattern in receptive vs. prereceptive human endometria and contrasted the results with gene expression in the highly adhesive cell line (to JAR cells and mouse blastocysts) RL95-2 vs. HEC-1A, a cell line with markedly less adhesiveness. IGF-binding protein-related protein 1 (IGFBP-rP1), also known as IGFBP-7/mac 25, was the second most up-regulated gene in both of the investigated models. These results were corroborated by performing RT-PCR on the same RNA samples and validated by quantitative fluorescent RT-PCR and in situ hybridization in endometrium throughout the menstrual cycle. Interestingly, a 35-fold increase in expression during the receptive phase was compared with the prereceptive phase followed by a sharp increase in the late luteal. Further quantitative fluorescent RT-PCR experiments using the epithelial and stromal endometrial fraction throughout the menstrual cycle confirmed that IGFBP-rP1 expression was localized in the epithelial and stromal compartments and up-regulated mainly in the latter. In situ experiments confirmed the endometrial localization and regulation of IGFBP-rP1 mRNA. At the protein level, IGFBP-rP1 was localized by immunohistochemistry at the apical part of the luminal and glandular epithelium, stromal, and endothelial cells. In conclusion, using a genomic approach with a combined experimental design of receptivity in vivo and in vitro, we have discovered the implication of IGFBP-rP1 in endometrial physiology, which seems related to endometrial receptivity.