gebhart/patrepeval huggingface dataset:
Development of a remotely accessible integrated circuit test facility based on telepresence (2002)

This paper presents experiences learned from an ongoing research in employing telepresence technologies to facilitate an Internet-based remote IC (integrated circuits) testing laboratory at R.I.T. An instrumentation server has been developed using National Instrument's Labview 5.0 to interface and control a number of GPIB-enabled lab instruments. By utilizing LabView's Open Reference VI (virtual instruments) client/server model, an authorized user can remotely execute the VI graphical interface to manipulate various lab equipment via the Internet. The system is designed mainly for remote inspection and testing of packaged integrated circuits. Multi-platform accessibility is a key objective when designing the client module, which consists of the graphical VI interface. Any user with a computer (Windows, UNIX, or Macintosh) that is capable of Internet access, installed with a Java-enabled web browser, and has the ability to run Labview 5.0 will be able to access the networked lab equipment.
Fully Biodegradable Self-Rolled Polymer Tubes: A Candidate for Tissue Engineering Scaffolds (2011)

We report an approach for the fabrication of fully biodegradable self-rolled tubes based on patterned polysuccinimide/polycaprolactone bilayers. These polymers are biocompatible, biodegradable, produced industrially, and are already approved for biomedical purposes. Both polycaprolactone and polysuccinimide are hydrophobic and intrinsically water-insoluble. Polysuccinimide, however, hydrolyzes in physiological buffer environment yielding water-swellable polyaspartic acid that causes the rolling of the polymer bilayer and formation of tubes. We demonstrate the possibility to encapsulate yeast cells using self-rolled tubes.
Cysteine proteinase 1 (CP1), a cathepsin L‐like enzyme expressed in the <i>Drosophila melanogaster</i> haemocyte cell line mbn‐2 (1997)

We have isolated cDNA clones encoding the full-length Drosophila melanogaster cysteine proteinase 1 (CP1). The clones were isolated from the Drosophila melanogaster haemocytic mbn-2 cell line, where the gene is relatively strongly expressed, giving a transcript of 1.6 kb in size. We present the sequence encoding the full-length protein, and deduced the genomic organization of the gene by comparison to previously published genomic partial sequence data. Immunofluorescence shows that CP1 is localized in small granules, probably lysosomes, in mbn-2 cells. The data presented suggest a role for cysteine proteinase in immune functions in insects. It is likely to participate in the degradation of internalized material in phagocytic cells.
Meeting on radio interferometry techniques for geodesy (1979)

Developments and applications of radio interferometry techniques for geodesy were the subjects of a meeting at the Massachusetts Institute of Technology in Cambridge and the Northeast Radio Observatory Corporation's Haystack Observatory in Westford, Massachusetts, on June 19–21,1979. One hundred thirty persons from eight countries attended the meeting, which was cosponsored by the American Geophysical Union and the U.S. National Aeronautics and Space Administration (NASA), Office of Space and Terrestrial Applications, in cooperation with Special Study Group 2.51, on radio interferometry techniques, of the International Association of Geodesy (IAG). Fifty‐four papers treated practically all aspects of this rapidly maturing geodetic method. Papers presented at the meeting are being collected in a NASA Conference Publication by Robert J. Coates of NASA Goddard Space Flight Center. This publication should be available by January 1980.
MULTIDISCIPLINARY OPTIMIZATION IN TURBOMACHINERY DESIGN (2000)

This paper investigates particular aspects of performing multidisciplinary optimizations in different turbomachinery design steps. The differences in the optimization approaches and used methods in preliminary and final design steps are shown. An optimization environment is developed, which supports multidisciplinary turbomachinery design. The general concept and components are explained. Some of the implemented methods and tools, which are used particularly in multidisciplinary optimization, are presented. Examples show the potential of the proposed methods. Pareto-optimization enables multi-objective optimizations, very important in preliminary design steps. Various objectives are optimized concurrently. An entire set of Pareto-optimal solutions, design variants, can be computed. Response surfaces promise to accelerate the entire design process.
A mathematical model for the bacterial oxidation of a sulfide ore concentrate (1994)

The effect of dilution rate and feed solids concentration on the bacterial leaching of a pyrite/arsenopyrite ore concentrate was studied. A mathematical model was developed for the process based on the steady-state data collected over the range of dilution rates (20 to 110 h) and feed solids concentrations (6 to 18% w/v) studied. A modified Monod model with inhibition by arsenic was used to model bacterial ferrous ion oxidation rates. The model assumes that (i) pyrite and arsenopyrite leaching occurs solely by the action of ferric iron produced from the bacterial oxidation of ferrous iron and (ii) bacterial growth rates are proportional to ferrous ion oxidation rate. The equilibrium among the various ionic species present in the leach solution that are likely to have a significant effect on the bioleach process were included in the model. (c) 1994 John Wiley & Sons, Inc.
Doping Effects from Neutral B<sub>2</sub>H<sub>6</sub> Gas Phase on Plasma Pretreated Si Substrates as a Possible Process in Plasma Doping (2005)

In a low-energy plasma doping process, the contribution of not only ionized species but also neutral species to the doping process should be considered. To investigate such a contribution, experiments involving gas phase doping combined with Ar plasma pretreatment were carried out. As a result, a significant increase in boron dose from a neutral gas phase was observed when the substrate surface was subjected to Ar plasma pretreatment prior to exposure to neutral B 2 H 6 /He gas. Through a comprehensive study of the effects of plasma pretreatment and gas exposure conditions on the boron dose from the neutral gas phase, the substrate temperature at which the surface was exposed to the neutral B 2 H 6 /He gas after the plasma pretreatment was observed to significantly increase the boron dose.
New Type Femtosecond Streak Tube (1989)

The mechanism of intensity dependent recorded pulse broadening in the magnetic focusing femtosecond streak tube has been analyzed. The results have shown that it is due to broadening of an electron packet along the tube axis induced by space charge effects between the photocathode and the deflection electrode. Based on these analyses, a new tube with high dynamic range has been proposed. Photoelectron beam is swept by the deflection electrode immediately after it has been emitted from the photocathode. After passing the deflection electrode, the beam is focused by the focusing electron lens on the output screen. The temporal resolution of the tube is -500fs. Improved results are being obtained.
Electric Field Distribution in Multilayer Thin-film Polarizers (1989)

Abstract The distribution of electric-field amplitude inside multilayer thin-film polarizers is evaluated for various polarizer designs. The polarizers, based on (H/2, L, H/2) as the basic stack, show higher field amplitude than those based on all quarter-wave layers. Here H and L represent quarter-wave layers of high- and low-index materials respectively. It has been pointed out that, to avoid damage to the polarizers in high-power laser systems, it is necessary to know the field distribution inside the layers both for radiation incident from the air-multilayer interface as well as the glass-multilayer interface. Some implications of the positioning of thin-film polarizers in Faraday isolators used in high-power laser chains are discussed in relation to the susceptibility of these polarizers to optical damage. The results indicate that the liquid-prism MacNeille polarizer shows a higher damage threshold, which can possibly be further improved by increasing the angle of incidence at the multilayer.
Sizzle: A Standards-Based End-to-End Security Architecture for the Embedded Internet (Best Paper) (2005)

This paper introduces Sizzle, the first fully implemented end-to-end security architecture for highly constrained embedded devices. According to popular perception, public-key cryptography is beyond the capabilities of such devices. We show that elliptic curve cryptography (ECC) not only makes public-key cryptography feasible on these devices, it allows one to create a complete secure Web server stack including SSL, HTTP and user application that runs efficiently within very tight resource constraints. Our small footprint HTTPS stack needs less than 4 KB of RAM and interoperates with an ECC-enabled version of the Mozilla Web browser. We have implemented Sizzle on the 8-bit Berkeley/Crossbow Mica2 "mote" platform where it can complete a full SSL handshake in less than 4 seconds (session reuse takes under 2 seconds) and transfer 450 bytes of application data over SSL in about 1 second. We present additional optimizations that can further improve performance. To the best of our knowledge, this is the world's smallest secure Web server (in terms of both physical dimensions and resources consumed) and significantly lowers the barrier for connecting a variety of interesting new devices (e.g. home appliances, personal medical devices) to the Internet without sacrificing end-to-end security.
New anti-epileptic drugs (1999)

Epilepsy represents the most common serious neurological disorder, with a prevalence of 0.4 - 1%. Approximately 30% of patients are resistant to currently available drugs. New anti-epileptic drugs are needed to treat refractory epilepsy, improve upon current therapies, improve the prognosis of epilepsy and to prevent the epileptogenic process. Designing compounds with specific physiological targets would seem the most rational method of anti-epileptic drug development, but results from this approach have been disappointing; the widespread screening of compounds in animal models has been much more fruitful. Older methods of animal screening have used acute seizure models, which bear scant relationship to the human condition. More modern methods have included the development of animal models of chronic epilepsy; although more expensive, it is likely that these models will be more sensitive and more specific in determining anti-epileptic efficacy. In this review, we consider the possible physiological targets for anti-epileptic drugs, the animal models of epilepsy, problems with clinical trials and ten promising anti-epileptic drugs in development (AWD 131-138, DP16 (DP-VPA), ganaxolone, levetiracetam, losigamone, pregabalin, remacemide, retigabine, rufinamide and soretolide). Perhaps the most important advances will come about from the realisation that epilepsy is a symptom, not a disease. Preclinical testing should be used to determine the spectrum of epilepsies that a drug can treat, and to direct later clinical trials, which need to select patients based on carefully defined epilepsy syndromes and aetiologies. Not only will such an approach improve the sensitivity of clinical trials, but also will lead to a more rational basis on which to treat.
A 48-to-12 V Cascaded Resonant Switched-Capacitor Converter for Data Centers with 99% Peak Efficiency and 2500 W/in<sup>3</sup> Power Density (2019)

Resonant switched-capacitor (ReSC) converters are promising alternatives for conventional SC and magnetic-based converters, with the potential to achieve simultaneously higher efficiency and higher power density. Since ReSC converters operate in resonant mode, zero current switching (ZCS) occurs naturally and the V-I overlap switching loss is eliminated. To further reduce the switching loss (transistor C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">oss</sub> loss) and improve the light-load efficiency, zero voltage switching (ZVS) is desired. In this work, a ZVS control technique is implemented on a cascaded resonant based intermediate bus converter for 48-to-12 V data center power delivery, on a 720 W hardware prototype. The efficiency is maintained above 97% starting from 3% of the rated load, and has a peak of 99% (including gate drive loss). In addition, the prototype has a very high power density of 2500 W/in <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> .
Simulation of wake vortex effects for UAVs in close formation flight (2009)

Abstract This paper addresses the development of multiple UAV deployment simulation models that include representative aerodynamic cross-coupling effects. Applications may include simulations of autonomous aerial refuelling and formation flying scenarios. A novel wake vortex model has been developed and successfully integrated within a Matlab/Simulink simulation environment. The wake vortex model is both sufficiently representative to support studies of aerodynamic interaction between multiple air vehicles, and straightforward enough to be used within real time or near real time air-to-air simulations. The model integration process is described, and computational results of a two-vehicle-formation flight are presented.
Low-power photon upconversion in organic glasses (2014)

Green-to-blue upconverting molecular glasses consisting of a metal octaethylporphyrin sensitizer and a diphenylanthracene derivative as an emitting matrix are reported.
Native fluorescence and excitation spectroscopic changes in Bacillus subtilis and Staphylococcus aureus bacteria subjected to conditions of starvation (2003)

Fluorescence emission and excitation spectra were measured over a 7-day period for Bacillus subtilis (Bs), a spore-forming, and Staphylococcus aureus (Sa), a nonspore-forming bacteria subjected to conditions of starvation. Initially, the Bs fluorescence was predominantly due to the amino acid tryptophan. Later, a fluorescence band with an emission peak at 410 nm and excitation peak at 345 m, from dipicolinic acid, appeared. Dipicolinic acid is produced during spore formation and serves as a spectral signature for detection of spores. The intensity of the 410-nm band continued to increase over the next 3 days. The Sa fluorescence was predominantly from tryptophan and did not change over time. In 6 of the 17 Bs specimens studied, an additional band appeared with a weak emission peak at 460 cm and excitation peaks at 250, 270, and 400 nm. The addition of beta-hydroxybutyric acid to the Bs or the Sa cultures resulted in a two-order of magnitude increase in the 460-nm emission. The addition of Fe2+ quenched the 460 emission, indicating that a source of the 460-nm emission was a siderophore produced by the bacteria. We demonstrate that optical spectroscopy-based instrumentation can detect bacterial spores in real time.
Preservation of specific RNA distribution within the chromatin-depleted nuclear substructure demonstrated by in situ hybridization coupled with biochemical fractionation. (1991)

Biochemical fractionation procedures previously shown to remove 95% of cellular protein, DNA, and phospholipid, were combined with fluorescence in situ hybridization to provide a critical evaluation of the retention and spatial preservation of specific primary transcripts within the chromatin-depleted nuclear substructure, operationally defined as the nuclear "matrix." This unique approach made it possible to directly address whether nuclear extraction procedures preserve, create, or destroy ribonucleoprotein filament structures. Comparison of nuclei before and after fractionation demonstrated that localized foci or "tracks" of specific nRNA are unambiguously retained in the nuclear matrix preparation. Two well-characterized nuclear fractionation procedures were used and three Epstein-Barr virus-infected cell types investigated, including latently and permissively infected cells carrying integrated or episomal genomes. The EBV primary transcripts as well as nucleolar RNA were preserved within the remaining nuclear substructure with unambiguous spatial and quantitative fidelity. Image processing and quantitative microfluorimetry, together with [3H]thymidine labeling of DNA, show that essentially 100% of the RNA signal intensity remained after removal of 85% of the DNA. That the native RNA distribution was unchanged was shown in other experiments in which the same individual nRNA tracks were examined before and after fractionation. Results conclusively demonstrate that the tight restriction of RNA to highly localized sites is independent of bulk DNA removal and of extensive extraction of proteins and phospholipids. Hence, this work provides direct visual evidence that the primary transcripts studied are localized via their binding to, or comprising part of, non-chromatin nuclear substructure.
Targeted Selected Reaction Monitoring Mass Spectrometric Immunoassay for Insulin-like Growth Factor 1 (2013)

Insulin-like growth factor 1 (IGF1) is an important biomarker of human growth disorders that is routinely analyzed in clinical laboratories. Mass spectrometry-based workflows offer a viable alternative to standard IGF1 immunoassays, which utilize various pre-analytical preparation strategies. In this work we developed an assay that incorporates a novel sample preparation method for dissociating IGF1 from its binding proteins. The workflow also includes an immunoaffinity step using antibody-derivatized pipette tips, followed by elution, trypsin digestion, and LC-MS/MS separation and detection of the signature peptides in a selected reaction monitoring (SRM) mode. The resulting quantitative mass spectrometric immunoassay (MSIA) exhibited good linearity in the range of 1 to 1,500 ng/mL IGF1, intra- and inter-assay precision with CVs of less than 10%, and lowest limits of detection of 1 ng/mL. The linearity and recovery characteristics of the assay were also established, and the new method compared to a commercially available immunoassay using a large cohort of human serum samples. The IGF1 SRM MSIA is well suited for use in clinical laboratories.
High Frame Rates and Human Vision: A View through the Window of Visibility (2013)

There is new interest in higher frame rates for digital cinema. The frame rate and subsequent processing have a large impact on the presence of artifacts in the final presentation. The structure of these artifacts is revealed by transforming the sequence of frames into the spatiotemporal frequency domain. The visibility of these artifacts can be determined through application of a tool called the window of visibility. This is a simplified representation of human visual sensitivity to spatial and temporal frequencies. This paper describes the capture and display of movies in signal processing terms. It shows how the several steps in the process can by represented in space and time and in spatial and temporal frequency. It then introduces the window of visibility as a simplified version of the human visual contrast sensitivity function. It shows how the tool can be used to compute the lowest artifact-free frame rate under simplified circumstances. It also shows how it can be used to visualize the impact of various steps in processing the image sequence. Finally, the paper describes the influence of luminance, eccentricity, color, and eye movements on the size and shape of the window of visibility. In conclusion, the tool provides a useful aid to understanding the role of human visual sensitivity in the selection of frame rates and frame processing. The paper also provides an interactive demonstration that allows exploration of the trade-offs in movie capture and display.
I. VORBEREITUNG UND ERSTE ERFAHRUNG DER MILITÄRREGIERUNG (1973)

Nachrichtendienstes OSS in Europa war Dorn von Anfang an in die Ausbildung der Militrregierungsoffiziere eingeschaltet und erlebte beim alliierten Einmarsch die ersten Begegnungen mit der Lage in Deutschland mit. Seine Erinnerungen an diese Zeit und seine Notizen beschreiben ver- schiedene Aspekte zweier Llauptsachverhalte: 1. da die Verhltnisse in Deutschland anders waren, als man bei den Besatzungsplanungen angenommen hatte, und da man insofern zunchst weitgehend auf Improvisation angewiesen war; 2. da die Ausbildung der Militrregierungsoffiziere und lngerfristige Planungen fr eine Be- satzungspolitik in Deutschland daran scheiterten, da die Armee nach eigenem Gut- dnken improvisierte und
The Influence of Electric Current on Crack Propagation in Thermal Fatigue Tests. (1986)

Abstract : The use of a benchmark or model problem to estimate errors in stress intensity factors and local temperatures in thermal-mechanical fatigue testing which uses large electric currents for heating has shown that this mode of testing results in a more severe stress state than if conventional heating methods are used. The reason for the more severe stress state is that the application of a constant voltage across a cracked specimen results in a singular current and, consequently, a singular heat source. The singular heat source does not result in a temperature singularity, however, so the temperature remains bounded at the crack tip. The relative discrepancy between conventional heating fatigue testing and resistance heating fatigue is quite dependent on crack size and materials properties: primarily thermal and electrical conductivity and linear thermal expansion. Materials exhibiting low electrical resistance and high thermal expansion are, in general, more susceptible to this mode of thermal loading. Simple expressions for estimating the contribution of electric current to the stress intensity factor and local temperature field were developed. These expressions are estimated in light of some basic assumptions made during problem formulation. The validity and consequence of some of these assumptions are discussed.