gebhart/patrepeval huggingface dataset:
Recurrence plots of sunspots, solar flux and irradiance (2008)

The paper shows the recurrence and cross recurrence plots of three time series, concerning data of the solar activity. The data are the sunspot number and the values of solar radio flux at 10.7 cm and of solar total irradiance, which are known as highly correlated. To compare the series, the radio flux and irradiance values are monthly averaged. Recurrence plots display the oscillating behaviour with remarkable features. Moreover, cross recurrence plots help in identifying time lags between the sunspot number maximum and the maximum of radio or irradiance signals, in circumstances where the data values are highly dispersed. Image processing is useful too, in enhancing the monitoring. An interesting behaviour is displayed by cross recurrence plots of irradiance, which are not symmetric with respect to the line of identity.
A general view on probabilistic logic programming (2003)

Probabilistic logic programming oers a way of dealing with both relational and uncertain knowledge. As research in this eld has lead to numerous formalisms, originating from diverse origins, it is not always easy to get a clear picture of this domain. In this work, we present a general \\framework&quot; for looking at such formalisms. We show how several actual formalisms t into this view and how this leads to a clearer view on the relationships between them.
Turning the tide: preserving community mental health services. (2003)

As part of its continuing mission to serve trustees and staff of health foundations and corporate giving programs, Grantmakers In Health (GIH) convened a group of experts from the fields of philanthropy, research, government, and health care on September 19, 2002 to examine the status of community-based services for people with mental disorders. This Issue Dialogue, "Turning the Tide: Preserving Community Mental Health Services," explored how health grantmakers can support community programs that provide critical mental health intervention and treatment services to children and adults. This Issue Brief synthesizes key points from the day's discussion with a background paper previously prepared for Issue Dialogue participants. It includes quantitative and qualitative information on mental health, as well as profiles of public sector, private sector, and grantmaker strategies for promoting improvements.
Molecular analysis of the same HIV peptide functionally binding to both a class I and a class II MHC molecule. (1995)

Although several peptides have been found to bind to both class I and class II molecules, the basis for this binding of the same peptide to two classes of MHC molecules has not been compared previously. We have analyzed one such peptide, P18 from the V3 loop of HIV-1 gp160, which we have previously shown to be recognized by CD8+ CTL with the class I molecule H-2Dd, and by CD4+ Th cells with the class II molecule I-Ad. With the use of truncated and substituted peptides, we found that the minimal core peptides are very similar, that the residues required for class I binding precisely fit the recently identified consensus motif for peptides binding to Dd (XGPX[R/K/H]XXX(X) [L/I/F]), and that at least three of the same residues are involved in binding to class II I-Ad. In addition, several of the same residues are involved in TCR interaction when the peptide is presented by class I and class II molecules. Modeling shows results to be consistent with the crystal structure of a peptide-class II MHC complex. Thus, the recognition of this versatile peptide by CD4+ Th cells with class II MHC molecules and by CD8+ cytotoxic T cells with class I MHC molecules is remarkably similar in both the core peptide used and the role of different residues in the ternary complex.
Effect of Melatonin on the Luteinizing Hormone Release Induced by Clomiphene and Luteinizing Hormone-Releasing Hormone (1976)

The effect of melatonin on the LH-release response after the administration of synthetic LH-RH and clomiphene citrate was investigated in adult male rats. The sc administration of melatonin (1 mg/day) for 6 days produced a significant decrease in serum LH levels and in seminal vesicles and ventral prostate weights. On the other hand, the daily injection of 0.01 mg/100 g of body weight of clomiphene citrate during 6 days significantly stimulated LH levels and the weights of the accessory sex glands. Simultaneous treatment with melatonin and clomiphene produced an inhibitory effect similar to that obtained with melatonin alone. Neither pretreatment with melatonin alone. Neither pretreatment with melatonin (1 mg/day, sc for 6 days) nor its simultaneous iv administration (500 mug) with 75 ng of LH-RH modified the LH-release in response to the hypothalamic hormone. The fact that melatonin was able to suppress the effect of clomiphene, which is probably exerted at the hypothalamic level, but not the actiion of LH-RH on the pituitary, appears to indicate that the hypothalamus may be the site involved in the inhibitory effect of the pineal principle on the reproductive function.
Sound-based remote real-time multi-device operational monitoring system using a Convolutional Neural Network (CNN) (2021)

Smart factory is the main keyword in the field of manufacturing processes about the fourth industrial revolution. To realize the smart factory, making all pieces of device into smart devices that are connected to the centralized system to enable a real-time exchange of information is essential. Sound can be efficient means to make devices as smart devices because sound can contain the status information of various devices simultaneously, and it can be recorded easily outside of a device using only a microphone. In this study, multi-device operation monitoring system by analyzing sound is developed. Mic arrays for acquiring the sound were installed at the outside the devices and recorded the sounds from several devices simultaneously. By analyzing the recorded sound with log-mel spectrogram and Convolutional Neuron Network (CNN), the system could detect the operational status of three devices with an accuracy of 71–92 %. To improve the performance, virtual data set was created by composition of individual device operating sounds of different intensities. With this virtual data set, accuracy can be enhanced to 87 % ∼ 99 % accuracy and, required sound data amount could be reduced. Developed system was applied successfully in monitoring experiments in two different environments: a workshop in which hand-operated device was used and a factory with a computer numerical control machine and verifying the performance.
Lightweight closure conversion (1997)

We consider the problem of lightweight closure conversion, in which multiple procedure call protocols may coexist in the same code. A lightweight closure omits bindings for some of the free variables of the procedure that is represents. Flow analysis is used to match the protocol expected by each procedure and the protocol used at its possible call sites. We formulate the flow analysis as a deductive system that generates a labeled transition system and a set of constraints. We show that any solution to the constraints justifies the resulting transformation. Some of the techniques used are similar to those of abstract interpretation, but others appear to be novel.
Deep Tracking on the Move: Learning to Track the World from a Moving Vehicle using Recurrent Neural Networks (2016)

This paper presents an end-to-end approach for tracking static and dynamic objects for an autonomous vehicle driving through crowded urban environments. Unlike traditional approaches to tracking, this method is learned end-to-end, and is able to directly predict a full unoccluded occupancy grid map from raw laser input data. Inspired by the recently presented DeepTracking approach [Ondruska, 2016], we employ a recurrent neural network (RNN) to capture the temporal evolution of the state of the environment, and propose to use Spatial Transformer modules to exploit estimates of the egomotion of the vehicle. Our results demonstrate the ability to track a range of objects, including cars, buses, pedestrians, and cyclists through occlusion, from both moving and stationary platforms, using a single learned model. Experimental results demonstrate that the model can also predict the future states of objects from current inputs, with greater accuracy than previous work.
Damped gyromagnetic switching (2000)

The gyromagnetic switching behavior of a single-domain grain or particle with uniaxial magnetocrystalline and shape anisotropy is solved analytically by the gyromagnetic torque equation using physically plausible Gilbert damping. The sole restriction is that the anisotropy easy axis and the applied field be collinear. The analytical solution for the magnetization switching time is then used to calculate precisely various phenomena which occur in pulsed-current stripline testing of magnetic recording storage media. Also, the analytic relationship between the polar and azimuthal angles of the magnetization during damped precession is derived.
Combination of Advanced Optical Modelling with Electrical Simulation for Performance Evaluation of Practical 4-terminal Perovskite/c-Si Tandem Modules (2016)

<p>The perovskite solar cell is considered a promising candidate as the top cell for high-efficiency tandem devices with crystalline silicon (c-Si) bottom cells, contributing to the cost reduction of photovoltaic energy. In this contribution, a simulation method, involving optical and electrical modelling, is established to calculate the performance of 4-terminal (4T) perovskite/c-Si tandem devices on a mini-module level. Optical and electrical characterization of perovskite and c-Si solar cells are carried out to verify the simulation parameters. With our method, the influence of transparent conductive oxide (TCO) layer thickness of perovskite top cells on the performance of tandem mini-modules is investigated in case of both tin-doped indium oxide (ITO) and hydrogen-doped indium oxide (IO:H). The investigation shows that optimization of TCO layer thickness and replacement of conventional ITO with highly transparent IO:H can lead to an absolute efficiency increase of about 1%. Finally, a practical assessment of the efficiency potential for the 4T perovskite/c-Si tandem mini-module is carried out, indicating that with a relatively simple 4T tandem module structure the efficiency of a single-junction c-Si mini-module (19.3%) can be improved by absolute 4.5%.</p>
Influence of repeated washings with soap and synthetic detergents on pH and resident flora of the skin of forehead and forearm. Results of a cross-over trial in health probationers (1987)

Ten healthy individuals washed their forehead and forearm twice a day over consecutive periods of four weeks with soap and synthetic detergents or vice versa (cross-over design). In general the pH values were higher during the period when soap was applied (the mean pH differed by 0.3 units, p less than 0.01). As a rule the counts of coagulase-negative staphylococci were not much altered. The number of propionibacteria, however, was markedly higher when soap was used (p = 0.02 and 0.01 resp.). At the forehead there was a clear correlation between bacterial counts and skin pH both with propionibacteria (0.56, p less than 0.001) and staphylococci (0.51, p less than 0.001). At the forearm only the former proved true (0.24, p less than 0.05). Thus the skin pH seems to be open to long-standing changes according to the preferred washing habits which may also be of major influence on the composition of the cutaneous bacterial flora.
Lifestyle Intervention in Obese Children With Variations in the Melanocortin 4 Receptor Gene (2008)

Because information on weight changes after lifestyle intervention in children with mutations in the melanocortin 4 receptor (MC4R) gene is scarce, we compared weight changes after lifestyle intervention between children with and without MC4R variations. A group of 514 overweight children (aged 5-16 years), who presented to participate in a 1-year lifestyle intervention based on exercise, behavior, and nutrition therapy were screened for MC4R mutations. For comparison, children with MC4R mutations leading to reduced receptor function (group A) were each of them randomly matched with five children of same age and gender without MC4R mutations (group B). Changes of weight status were analyzed as change of BMI standard deviation scores (BMI-SDSs). Furthermore, 16 children (3.1%) harbored MC4R mutations leading to reduced receptor function, and 17 (3.3%) children carried variations not leading to reduced receptor function. Children with and without MC4R mutations reduced their overweight at the end of intervention to a similar degree (P = 0.318 between groups based on an intention-to-treat analysis). The maintenance of weight loss after intervention among children with MC4R mutations leading to reduced receptor function failed in contrast to children without such mutations (P < 0.001 adjusted for BMI-SDS at baseline, age, and gender in an intention-to-treat analysis). In conclusion, children with MC4R mutations leading to reduced receptor function were able to lose weight in a lifestyle intervention but had much greater difficulties to maintain this weight loss supporting the impact of these mutations on weight status.
Über hochacide Kohlenwasserstoffe, VII<sup>1)</sup>. Die Lichtabsorption der Anionen hochacider Kohlenwasserstoffe (1965)

Abstract Die Anion‐Spektren von Phenyl‐ und Biphenylen‐substituierten Alkenen wurden in Dimethylsulfoxyd bzw. Dimethylformamid im Bereich von 300—800 mμ aufgenommen. Die Abhängigkeit der Lage der längstwelligen Absorptionsbande von der Struktur wird diskutiert. — Für einen Vergleich mit den Anion‐Spektren wurden in einigen Fällen auch Lösungen der entsprechenden Carboniumsalze und der freien Radikale vermessen. Die Darstellung von 1.1.5.5‐Tetraphenyl‐ und 1.1.5.5‐Bis‐biphenylen‐pentadienyl‐perchlorat aus Tetraarylpentadienolen wird beschrieben. Die z. T. sehr instabilen Kationen anderer Kohlenwasserstoffe entstehen aus den entsprechenden C‐Radikalen durch Disproportionierung in Gegenwart von Perchlorsäure. Die ESR‐Spektren der freien Radikale werden kurz diskutiert.
A phase I dose-ranging trial of monthly infusions of zoledronic acid for the treatment of osteolytic bone metastases. (2001)

Bisphosphonates are potent inhibitors of bone resorption and provide a therapeutic benefit for patients with bone metastases. Zoledronic acid is a highly potent, nitrogen-containing bisphosphonate. In the present trial, we assessed the safety and tolerability of increasing doses of zoledronic acid and its effects on urinary markers of bone resorption in cancer patients with bone metastases. Fifty-nine cancer patients with bone metastases were enrolled sequentially into one of 8 treatment groups in the core protocol. Each patient received a 5-min i.v. infusion of 0.1, 0.2, 0.4, 0.8, 1.5, 2, 4, or 8 mg zoledronic acid monthly for 3 months. Patients were monitored for clinical findings, adverse events, electrocardiograms, markers of bone resorption, as well as routine hematology, blood chemistries, and urinalysis. Thirty patients who demonstrated a radiographic response to treatment or stable disease in the core protocol were enrolled in a humanitarian extension protocol and continued to receive monthly infusions. Zoledronic acid was well tolerated at all dose levels. Adverse events reported by >10% of patients included skeletal pain, nausea, fatigue, upper respiratory tract infection, constipation, headache, diarrhea, and fever. Three patients in the core protocol and one patient in the extension protocol experienced grade 3 skeletal pain, "flu-like" symptoms, or hypophosphatemia, which were possibly related to treatment; all recovered completely. Adverse events were reported with similar frequency across all of the dosage groups. Zoledronic acid resulted in sustained, dose-dependent decreases in urinary markers of bone resorption. Zoledronic acid was safe and well tolerated and demonstrated potent inhibition of bone resorption.
Use of a New Tumor Marker, Urinary NMP22, in the Detection of Occult or Rapidly Recurring Transitional Cell Carcinoma of the Urinary Tract Following Surgical Treatment (1996)

NMP22 was highly predictive of tumor status at followup cystoscopy. This quantitative, noninvasive assay, with high negative predictive value (86%) and sensitivity to detect malignancy (100% for invasive disease and 70% overall), may be a helpful adjunct to cytology and endoscopy for monitoring disease status after endoscopic tumor resection.
Significant reduction of crossing loss using polynorbornene based GI-core optical waveguide (2012)

In this paper, we demonstrate that crossed multimode graded-index (GI) optical waveguides show very low crossing loss. We actually fabricate multiple-perpendicularly-crossed waveguides with GI core (WG2), and quasi-GI waveguides (WG1) that have a GI profile only in the horizontal direction while a step-index profile in the vertical direction, and then compared with the SI core crossed waveguides (WG3) previously reported. We confirm that an optical loss of 0.003 dB per 90-degree crossing is observed in WG2, which is much lower than those of WG3 (0.023 dB per crossing) and even WG1 (0.017 dB per crossing). In addition, we also demonstrate that WG2 with different crossing angles from 30 to 80 degrees always shows lower crossing loss than WG1 and WG3 with the same crossing angles. This could be a specific characteristic of GI-core: that is a strong optical confinement effect. We expect that this unique GI-core waveguide will be one of the promising components giving a great impact on high performance computing systems (HPCs) in the near future.
<title>Application of an aerial image measurement system to mask fabrication and analysis</title> (1994)

Application of an Aerial Image Measurement System (AIMS<SUP>TM</SUP>) to binary and phase- shift mask fabrication and evaluation is described. The AIMS tool, an optical system which measures the aerial image directly from a mask, provides rapid feedback on lithographic performance for a variety of stepper configurations through modifications of the wavelength, numerical aperture, and illuminator design. The AIMS tool has been applied during the implementation of an alternating phase-shift mask (PSM) fabrication process in order to understand the impact of the etched-quartz sidewall on lithographic performance. AIMS measurements were used to extract the effective phase and transmission as a function of phase- etch depth as well as post-etch treatment condition. A set of basic test structures are proposed which can be used in conjunction with the AIMS tool to automate the extraction of transmission, phase, and second-level overlay for phase-shifting processes such as alternating and attenuating PSM.
Perineal Pudendal Neurotomy versus Selective Neurotomy of the S2 Somatic Contribution to the Pudendal Nerve (1992)

In 10 dogs that underwent bilateral electrode implantation on the S2 ventral root, 5 then underwent a bilateral total perineal neurotomy of the pudendal nerve (group A) at 3 months and 5 bilateral division of the S2 somatic contribution to the pudendal nerve (group B). The effects of these 2 types of neurotomy on the bladder and urethral responses to electrostimulation were compared after another 3 months. In group A, the proximal and mid-urethral responses decreased significantly [69.1% (p = 0.004) and 79.6% (p = 0.002), respectively]. A decrease in bladder response [26% (p = 0.089)], although not significant, was also found. In group B, the decrease in the proximal urethral response was significant [67.8% (p = 0.012)]; the mid-urethral response (56.8%) was not statistically significant (p = 0.134). The bladder response decreased by 73.6% (p = 0.034). Thus, although pudendal neurotomy can be effective in reducing the outlet resistance, the pudendal nerve may have an important role in the regulation of micturition in the dog. Preoperative testing of the effect of a pudendal neurotomy by temporary nerve blocks is warranted to avoid undesirable side effects such as a decrease in bladder excitability.
The origin of the electron distribution in SnO (2001)

Gradient corrected density functional theory calculations have been performed on SnO in the litharge and idealized CsCl structures with the litharge structure in good agreement with experiment. The CsCl structured SnO has a spherical electron density whereas the litharge structured SnO has a nonspherical electron distribution. Such asymmetry is often attributed to a sterically active lone pair formed by the 5s2 electrons which does not take part in chemical bonding. However, analysis of the density of states and band structures indicates that the situation is more complicated. In CsCl structured SnO mixing of the Sn 5s with the oxygen 2p electronic states results in filled bonding and antibonding combinations. The antibonding combinations, at the top of valence band, can interact with Sn 5p to stabilize the structure, only when in the distorted litharge structure resulting in the asymmetric electron density. This is in contrast to the classical theory of hybridization of the tin 5s and 5p orbitals to form a “lone pair” as the asymmetric electron distribution is the result of the tin–oxygen covalent interactions.
PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations (2019)

Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell checkpoint and plays a central role in regulating T cell exhaustion. Binding of PD-1 to its ligand, programmed death-ligand 1 (PD-L1), activates downstream signaling pathways and inhibits T cell activation. Moreover abnormally high PD-L1 expression on tumor cells and antigen-presenting cells in the tumor microenvironment mediates tumor immune escape, and the development of anti-PD-1/PD-L1 antibodies has recently become a hot topic in cancer immunotherapy. Here, we review the structure of PD-1 and PD-L1, the function of the PD-1/PD-L1 signaling pathway, the application of PD-1 or PD-L1 monoclonal antibodies and future directions for anti-PD-1/PD-L1 antibodies with combination therapies. Cancer immunotherapy using PD-1/PD-L1 immune checkpoint blockade may require more studies, and this approach may be curative for patients with many types of cancer in the future.
Safety as an Integrated Part of Platform Design (1991)

Abstract Traditionally, risk, and safety analyses have been carried out as separate activities relative to the conceptual and detailed design development of offshore installations. By continuous involvement from safety specialists, applying analytical tools as well as experience from former studies, it can be assured that –the correct decisions with respect to safety can be taken and incorporated without causing significant cost increase or schedule delays;–the need for additional compensating safety measures due to lack of inherent safe design is minimised;–the amount of redesign and reconstruction activities for safety reasons can be kept to a minimum. This paper addresses how safety studies can be incorporated into the project organisation and project schedule, and the timing and type of qualitative and quantitative safety studies during the various phases of a project development. Examples of application of risk and consequence studies as active design tools in recent developments are given.
Test of automotive embedded processors with high diagnostic resolution (2016)

In state-of-the-art automotive controllers, functional tests are used to check their integrity in the field. Features dedicated to production test of integrated circuits such as scan-chains are not applied in the embedded system. However, such test structures enable a more effective and diagnostic test, which improves the fault analysis in case of a system failure and even increases system reliability. To archive this, an access to the integrated test logic is required. In this paper, we describe a concept of a test access to embedded systems via high-speed standard interfaces. The extended test logic as well as an appropriate test routine are presented.