gebhart/patrepeval huggingface dataset:
DON’T FOLLOW ME - Spam Detection in Twitter (2010)

The rapidly growing social network Twitter has been infiltrated by large amount of spam. In this paper, a spam detection prototype system is proposed to identify suspicious users on Twitter. A directed social graph model is proposed to explore the “follower” and “friend” relationships among Twitter. Based on Twitter's spam policy, novel content-based features and graph-based features are also proposed to facilitate spam detection. A Web crawler is developed relying on API methods provided by Twitter. Around 25K users, 500K tweets, and 49M follower/friend relationships in total are collected from public available data on Twitter. Bayesian classification algorithm is applied to distinguish the suspicious behaviors from normal ones. I analyze the data set and evaluate the performance of the detection system. Classic evaluation metrics are used to compare the performance of various traditional classification methods. Experiment results show that the Bayesian classifier has the best overall performance in term of F-measure. The trained classifier is also applied to the entire data set. The result shows that the spam detection system can achieve 89% precision.
<title>Asynchronous multimedia annotations for web-based collaboration in biology education</title> (2005)

The focus of this paper is on the design, implementation, and validation of asynchronous multimedia annotations designed for Web-based collaboration in educational and research settings. The two key questions we explore in this paper are: How useful are such annotations and what purpose do annotations serve? What is the ease of use of our specific implementation of annotations? The context of our project has been in the area of multimedia information usage and collaboration in the biological sciences. We have developed asynchronous annotations for HTML and image data. Our annotations can be executed via any browser and require no downloads. They are stored in a central database allowing search and asynchronous access by all registered users. An easy to use user interface allows users to add, view and search annotations. We also performed a usability study that showed that our implementation of text annotations to validate our implementation.
Phototunable LCST of Water-Soluble Polymers: Exploring a Topological Effect (2011)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTPhototunable LCST of Water-Soluble Polymers: Exploring a Topological EffectYi Zhao†, Luc Tremblay‡, and Yue Zhao*†View Author Information† †Département de chimie and ‡Département de médecine nucléaire et de radiobiologie and Centre d'imagerie moléculaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, Québec, Canada J1K 2R1*E-mail: [email protected]Cite this: Macromolecules 2011, 44, 10, 4007–4011Publication Date (Web):April 21, 2011Publication History Received25 March 2011Revised13 April 2011Published online21 April 2011Published inissue 24 May 2011https://pubs.acs.org/doi/10.1021/ma200691shttps://doi.org/10.1021/ma200691sbrief-reportACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views4418Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Aromatic compounds,Dimerization,Photodimerization,Polymer solutions,Polymers Get e-Alerts
Modulation of the activity of human 17 α-hydroxylase-17,20-lyase (CYP17) by cytochrome <i>b</i>5: endocrinological and mechanistic implications (1995)

Using NADPH-cytochrome P-450 reductase as electron donor the homogeneous pig 17 alpha-hydroxylase-17,20-lyase (CYP17) was shown to catalyse the conversion of delta 5, as well as delta 4, steroids (pregnenolone and progesterone respectively) predominantly into the corresponding 17 alpha-hydroxylated products. The latter were then cleaved by the lyase (desmolase) activity of the enzyme into androgens. Cytochrome b5 stimulated both these activities, but its most noticeable effect was on the formation of delta 16-steroids, which compulsorily required the presence of cytochrome b5. These results on the pig enzyme confirm the original findings [Nakajin, Takahashi, Shinoda and Hall (1985) Biochem. Biophys. Res. Commun. 132, 708-713]. The human CYP17 expressed in Escherichia coli [Imai, Globerman, Gertner, Kagawa and Waterman (1993) J. Biol. Chem. 268, 19681-19689] was also purified to homogeneity and was found to catalyse the hydroxylation of pregnenolone and progesterone without requiring cytochrome b5. Like the pig CYP17, the human CYP17 also catalysed the cytochrome b5-dependent direct cleavage of pregnenolone into the delta 5,16-steroid, but unlike it the human enzyme did not cleave progesterone at all. 17 alpha-Hydroxypregnenolone was, however, cleaved into the corresponding androgen but only in the presence of cytochrome b5. 17 alpha-Hydroxyprogesterone was a poor substrate for the human CYP17; although it was converted into androstenedione in the presence of cytochrome b5 its K(m) was 5 times higher and Vmax. 2.6 times lower than those for the hydroxylation of progesterone. The endocrinological and mechanistic implications of these results are discussed.
Selective nature of gold-black deposits (1976)

Gold blacks made by evaporation from tungsten filaments in the presence of oxygen and in the absence of oxygen show different optical and electrical properties. The properties are found as a function of mass thickness for many different evaporation conditions. Electron microscopy was used to reveal the role of tungsten oxide in the deposit in breaking up the conducting paths and leading to selective optical behavior. Mie’s theory may be used to calculate the optical properties of a gold sol and, at least for the blacks with the smallest conducting regions, agreement with experiment is good. The application of metal sols to the production of selective surfaces is discussed.
Remote postamplifiers in repeaterless transmissionsystems (1995)

Three schemes for remotely pumping postamplifiers in a repeaterless system are investigated: Raman gain, Raman and EDFA, and separate fibre pumping of an EDFA. Using a dedicated pump fibre, 6 dB of budget improvement is predicted for 1000 mW of 1485 nm pump power. Experiments agree with the theoretical predictions within 0.75 dB.
Compartmental analysis of the steady-state distribution of 15O2 and H215O in total body. (1981)

It has been suggested that regional oxygen metabolism may be measured quantitatively by analysis of the steady-state distribution of O-15 (T1/2 = 122 sec). For this analysis we have developed a compartmental model that incorporates corrections due to clearance and recirculation of water of metabolism. The oxygen utilization rate is simply proportional to the local O-15 activity if water of metabolism is not recirculated from other tissues and is not lost to the circulation for a time long compared with the half-life of O-15. We evaluated the magnitude of biological metabolic water loss and uptake in the steady state. Our analysis indicates that the magnitude of these effects for rapidly exchanging tissues (such as cerebral gray and white matter), may preclude a simple, noninvasive, and quantitative determination of regional oxygen metabolism. Slowly exchanging compartments, however (such as skeletal muscle and perhaps some tumors), appear amenable to correction for clearance and recirculation effects with sufficient accuracy to make determinations of regional oxygen metabolism feasible.
Visual saliency estimation by nonlinearly integrating features using region covariances (2013)

Abstract To detect visually salient elements of complex natural scenes, computational bottom-up saliency models commonly examine several feature channels such as color and orientation in parallel. They compute a separate feature map for each channel and then linearly combine these maps to produce a master saliency map. However, only a few studies have investigated how different feature dimensions contribute to the overall visual saliency. We address this integration issue and propose to use covariance matrices of simple image features (known as region covariance descriptors in the computer vision community; Tuzel, Porikli, & Meer, 2006) as meta-features for saliency estimation. As low-dimensional representations of image patches, region covariances capture local image structures better than standard linear filters, but more importantly, they naturally provide nonlinear integration of different features by modeling their correlations. We also show that first-order statistics of features could be easily incorporated to the proposed approach to improve the performance. Our experimental evaluation on several benchmark data sets demonstrate that the proposed approach outperforms the state-of-art models on various tasks including prediction of human eye fixations, salient object detection, and image-retargeting.
The covariance function, bilocal approximation and homogenization of chiral-in-chiral composite materials (1999)

In continuation of an earlier paper on the application of the bilocal approximation (BA) within the framework of the strong property fluctuation theory (SPFT), an important restriction on the covariance function is lifted and the consequences numerically examined.
Enhanced resistance to experimental systemic candidiasis in tilorone-treated mice (2000)

Candida albicans is an increasingly important opportunistic fungal pathogen in immunocompromised patients. Natural killer (NK) cells constitute an important immune effector mechanism and are involved in the response to different pathological disorders. We wished to determine if this immune mechanism is involved in the specific response to C. albicans. Tilorone hydrochloride and related compounds have been described to display antiviral and antitumoral activity, as well as to enhance NK cell activity. In this study, we show the antimicrobial activity of different tilorone analogues and the enhanced resistance of tilorone-treated mice in experimental systemic candidiasis. We also present data suggesting that there is a correlation between NK cell activation and the resistance to experimental systemic candidiasis. Thus, it seems that the immunesurveillance of metastatic spread and the infection by C. albicans share some immune effector mechanisms, in particular activation of NK cells.
Differential phase tracking applied to Bragg gratings in multi-core fibre for high accuracy curvature measurement (2006)

High resolution quasi-static and dynamic curvature measurements are made by differential interferometric phase measurement of fibre Bragg gratings in separate cores of a multi-core fibre. A DC curvaturestability of 1×10−3m−1 and an AC curvature resolution of 1×10−4 m−1/Hz1/2 are reported.
A MICRODROPLET-BASED CAPACITIVE SENSING MATRIX FOR TACTILE APPLICATIONS (2014)

In this paper, we present a highly sensitive microdroplet-based interfacial capacitive sensor matrix device, achieving ultrahigh sensitivity of 0.4nF/kPa and minimal detectable pressure of 33Pa at a 330.2mm packaging. The microdroplet-based sensor is comprised of an array of nanoliter ionic droplets sandwiched between two flexible substrates with patterned transparent electrodes. The sensing principle primarily relies on high elasticity of the sensing droplet and large capacitance presented at the electrode-electrolyte interface.
Gonadotropin and Prolactin Pulsations in Hyperprolactinemic Women before and during Bromocriptine Therapy* (1984)

Pulsatile gonadotropin secretion and its relationship to PRL and estradiol (E2) secretion were investigated in 20 hyperprolactinemic amenorrheic women by obtaining serial blood samples for 6- to 24-h periods. Thirteen patients were restudied in the early follicular phase of the menstrual cycle (days 3-5) after ovulatory periods were established during bromocriptine therapy. In the hyperprolactinemic women, the number of LH peaks ranged from 0-12/24 h, and LH peak amplitude ranged from 0-1.7 mIU/ml. Serum E2 correlated with mean LH concentrations (P less than 0.001) and LH pulse frequency (P less than 0.05), but not with LH pulse amplitude. FSH pulsations were identified in 3 of the 20 women. There was no correlation between mean FSH concentrations and either serum E2 or PRL. There was a significant correlation between LH and FSH concentrations (P less than 0.001). During bromocriptine therapy, with comparable E2 concentrations, 5 of the 6 patients studied with blood sampling every 20 min for 24 h had a significant decrease (P less than 0.01) in the number of LH peaks per 24 h, with no change in LH peak amplitude. Mean FSH concentrations were unchanged in bromocriptine-treated patients; however, there was a significant (P less than 0.02) decrease in FSH levels during sleep. Serum PRL was normal in all bromocriptine-treated patients, but normal PRL secretory patterns were not reestablished, and there was no correlation between LH pulsations and serum PRL concentrations. We conclude that 1) hyperprolactinemic women have a heterogeneous pattern of pulsatile gonadotropin secretion; 2) serum E2 correlates with LH pulse frequency but not pulse amplitude; 3) LH pulsations and PRL pulsations are asynchronous in hyperprolactinemic women before and during bromocriptine therapy; and 4) normal PRL secretory patterns are not required for ovulatory function in hyperprolactinemic women treated with bromocriptine.
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells (2009)

Elevation of cAMP inhibits the proliferation and expression of transformed phenotype in several cell types, including breast cancer cells. Leptin has been shown to act as a mitogen/survival factor in many types of cancer cells. In the present work, we have studied the impact of cAMP elevation on leptin-induced proliferation of breast cancer cells. Here we report that treatment of estrogen receptor negative human breast cancer cell line MDA-MB-231 with leptin or cAMP elevating agents has positive and negative effects on cell proliferation, respectively. Surprisingly, we find that leptin strongly potentiates the anti-proliferative action of cAMP elevating agents, by concurring to cell cycle arrest at G1 phase and inducing apoptosis. Pretreatment with the PKA inhibitor KT-5720 completely prevented the anti-proliferative effects induced by the combination between leptin and cAMP elevating agents. The above anti-proliferative effects were paralleled by the decrease of cyclin D1 and A and by the increase of inhibitor p27kip1 cell cycle regulating protein levels. In these conditions we found also a strong decrease of anti-apopotic Bcl2 protein levels. Altogether, our data extend the evidence of adenylate cyclase/cAMP/PKA as a growth suppressor system and of leptin as a growth promoting factor in breast cancer cells. Remarkably, our results suggest that when cAMP levels are increased, leptin drives cells towards apoptosis, and that targeting both cAMP levels and leptin signalling might represent a simple novel way for therapeutic intervention in breast cancer.
Mannitol Preserves the Viscoelastic Properties of Hyaluronic Acid in an In Vitro Model of Oxidative Stress (2014)

This in vitro study demonstrates that mixing mannitol with HA protects the viscosupplement from ROS-mediated degradation and might therefore increase its intra-articular residence time without substantially modifying its rheological behavior. This in vitro study has to be followed by clinical trials designed to assess whether the addition of mannitol to HA might improve the efficiency and/or the duration of action of viscosupplementation.
Biological Effects and Mechanism of Action of Farnesyl Transferase Inhibitors (2000)

ADVERTISEMENT RETURN TO ISSUEPREVOpen ForumNEXTBiological Effects and Mechanism of Action of Farnesyl Transferase InhibitorsHena R. Ashar, Lydia Armstrong, Linda J. James, Donna M. Carr, Kimberley Gray, Arthur Taveras, Ronald J. Doll, W. Robert Bishop, and Paul T. KirschmeierView Author Information Department of Tumor Biology and Chemistry, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033 Cite this: Chem. Res. Toxicol. 2000, 13, 10, 949–952Publication Date (Web):September 29, 2000Publication History Received30 June 2000Published online29 September 2000Published inissue 1 October 2000https://pubs.acs.org/doi/10.1021/tx000138vhttps://doi.org/10.1021/tx000138vdiscussionACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views190Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cell physiology,Cells,Genetics,Inhibitors,Peptides and proteins Get e-Alerts
A Lightweight Encryption Method for Privacy Protection in Surveillance Videos (2018)

Privacy protection of surveillance videos is an important issue because of the pervasiveness of surveillance cameras. Region of interest (RoI) privacy protection prefers encrypting limited privacy-sensitive areas to encrypting the entire video because of the resource-tightened Internet of Things devices. However, many cryptographic technologies now applied in privacy protection, e.g., AES and RSA, are not efficient to meet the real-time requirement for surveillance videos. A lightweight encryption approach is then devised based on layered cellular automata (LCA). Using our approach, the extracted RoIs are fed into the initial state of an 8-layer cellular automata, which is driven by the randomly selected rules for the LCA's state transitions. As a result, all RoIs are encrypted independently and synchronously. The encrypted RoIs are stored at the camera side and can be used by authenticated users through an on-demand manner. The surveillance video without RoIs can be watched in real-time by any user online. Theoretical analyses and experimental results show that our approach is both efficient and effective.
Improvement of wear and corrosion resistance of ferrous alloys by post-nitrocarburizing treatments (2013)

Improvement of wear and corrosion resistance of ferrous alloys by post-nitrocarburizing treatments R. Sola, R. Giovanardi, P. Veronesi, G. Poli
Mechanism-based treatment of acne vulgaris: the value of combination therapy. (2005)

Acne vulgaris has multiple pathogenic mechanisms that act in concert to produce disease. Effective therapy addresses more than one pathogenic factor to speed resolution of disease. Typically, retinoids are used to inhibit comedo formation and an antibacterial is used to suppress Propionibacterium acnes (P. acnes). Using combinations of agents can enhance efficacy, but increase side effects. Therefore, the tolerability of a topical retinoid is important. Strategies to enhance retinoid tolerability include the use of new retinoids such as adapalene, new delivery systems such as the tretinoin microsphere delivery system, or alternative dosing schedules such as short contact or every other day (QOD).
Rational Gain Compensation for Attenuation in Cardiac Ultrasonography (1983)

A new method of compensating for the attenuation of ultrasound by chest wall, myocardium and blood has been devised by using an optimum threshold to distinguish between blood and myocardium. This allows changing receiver gain at rates suitable for either blood or myocardium for each line-of-sight forming a real-time image. Compensation artifacts arising from the effects of speckle or phase cancellation are minimized by using a one-bit digital filter after threshold detection. This method of compensation is a necessary first step toward quantitative two-dimensional echocardiography. ?NHLBI 14388
Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria (2011)

Risk factors for grades 2-4 acute graft-versus-host disease (GVHD) and for chronic GVHD as defined by National Institutes of Health consensus criteria were evaluated and compared in 2941 recipients of first allogeneic hematopoietic cell transplantation at our center. In multivariate analyses, the profiles of risk factors for acute and chronic GVHD were similar, with some notable differences. Recipient human leukocyte antigen (HLA) mismatching and the use of unrelated donors had a greater effect on the risk of acute GVHD than on chronic GVHD, whereas the use of female donors for male recipients had a greater effect on the risk of chronic GVHD than on acute GVHD. Total body irradiation was strongly associated with acute GVHD, but had no statistically significant association with chronic GVHD, whereas grafting with mobilized blood cells was strongly associated with chronic GVHD but not with acute GVHD. Older patient age was associated with chronic GVHD, but had no effect on acute GVHD. For all risk factors associated with chronic GVHD, point estimates and confidence intervals were not significantly changed after adjustment for prior acute GVHD. These results suggest that the mechanisms involved in acute and chronic GVHD are not entirely congruent and that chronic GVHD is not simply the end stage of acute GVHD.