gebhart/patrepeval huggingface dataset:
Design of the security alarm control system for LNG-fueled vessels (2017)

With the rapid growth of the economy, air pollution becomes increasingly serious and environment protection has attracted more attention. It is a fact that ships produce enormous air pollution emissions with high energy consumption and research has been constantly carried out on clean energy applications. LNG as an alternative clean marine fuel to run on ships is still at an initial stage. Different from traditional energy resources, LNG may generate risks in the process of application. Security alarm control system will effectively monitor risk sources preventing the occurrence of danger. Based on the deep analysis of the pros and cons of the existing structure and mode of security alarm control system of LNG-fueled vessels combined with the work and risk characteristics of marine engine, storage tanks and gas supply piping which have different danger sources, design a new type security alarm control system to optimize the structure design and logic control mode and implement functions of automatic detection, alarm and device control of combustible gas from risk sources. The system is stable and reliable with easy operation effectively reducing the risks of LNG-fueled ships.
Using stranger as sensors (2013)

MoboQ is a location-based real-time social question answering service deployed in the field in China. Using MoboQ, people can ask temporal and geo-sensitive questions, such as how long is the line at a popular business right now, and then receive answers that crowdsourced from other users in a timely fashion. To obtain answers for questions, the system analyzes the live stream from public microblogging service Sina Weibo to identify people who are likely to currently be at the place that is associated with a question and sends them the unsolicited question through the microblogging service from which they were identified. MoboQ was deployed in China at the beginning of 2012, until October of the same year, it was used to ask 15,224 questions by 35,214 registered users, and it gathered 29,491 answers; 74.6% of the questions received at least one answer, 28% received a first response within 10 minutes, and 51% of the questions got first answer within 20 minutes. In total, 91% of the questions successfully found at least one answer candidate, and they were sent to 162,954 microblogging service users. We analyze the usage patterns and behaviors of the real-world end-users, discuss the lessons learned, and outline the future directions and possible applications that could be built on top of MoboQ.
In situ recycling of contaminated soil uses bioremediation (1996)

OxyChem Pipeline Operations, primarily an ethylene and propylene products mover, has determined that substantial savings can be realized by adopting a bioremediation maintenance and recycling approach to hydrocarbon-contaminated soil. By this method, the soil can be recycled in situ, or in containers. To implement the soil-recycling program, OxyChem elected to use a soil remediator and natural absorbent product, Oil Snapper. This field maintenance material, based on an Enhanced Urea Technology, provides a diet to stimulate the growth of hydrocarbon-eating microbes. It works well either with indigenous soil microbes or with commercial microbes. The product is carried in field vehicles, which makes it immediately available when leaks or spills are discovered. Procedure for clean-up is to apply product and mix it into affected soil. Thus the contaminant is contained, preventing further migration; the contaminant is dispersed throughout the product, making it more accessible to the microbes; nutrients are immediately available to the microbes; and the material contributes aeration and moisture-retention properties.
Music-Based Individualized Relaxation Training (MBIRT): A Stress-Reduction Approach for the Behaviorally Disturbed Mentally Retarded (1989)

The purpose of this paper is to provide an overview of Music-Based Individualized Relaxation Training (MBIRT), a stress-reduction approach developed by the author for use with the behaviorally disturbed mentally retarded. MBIRT is defined, the various functions of music are discussed, and intervention strategies are described. A case study is provided to illustrate MBIRT applications.
A lightweight authentication protocol for mobile ad hoc networks (2005)

The characteristics of mobile ad hoc networks (MANETs) determine that the authentication approaches to protect routing and data packet transmission in MANETs should be lightweight and scalable. In this paper, we propose a lightweight authentication protocol, which utilizes one-way hash chain to provide effective and efficient authentication for communications between neighboring nodes in MANETs. The security properties and performance are also analyzed in the paper. The analysis shows that the protocol incurs low overhead penalty and achieves a tradeoff between security and performance.
A Letter to H. Repton, Esq. (2001)

SIR,THOUGH upon some accounts I might have wished that the printed Letter you have addressed to me, had been a private one; yet upon the whole I cannot be sorry that you have made it public. I am thereby enabled freely and openly to discuss the points of difference between us; to enforce some princi
Unsupervised Feature Selection for Accurate Recommendation of High-Dimensional Image Data (2007)

Content-based image suggestion (CBIS) targets the recommendation of products based on user preferences on the visual content of images. In this paper, we motivate both feature selection and model order identification as two key issues for a successful CBIS. We propose a generative model in which the visual features and users are clustered into separate classes. We identify the number of both user and image classes with the simultaneous selection of relevant visual features using the message length approach. The goal is to ensure an accurate prediction of ratings for multidimensional non-Gaussian and continuous image descriptors. Experiments on a collected data have demonstrated the merits of our approach. 1
Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization (2019)

Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation. How TGFβ signaling to microglia influences pathological retinal neuroinflammation is unclear. We discovered that ablation of the TGFβ receptor, TGFBR2, in retinal microglia of adult mice induced abnormal microglial numbers, distribution, morphology, and activation status, and promoted a pathological microglial gene expression profile. TGFBR2-deficient retinal microglia induced secondary gliotic changes in Müller cells, neuronal apoptosis, and decreased light-evoked retinal function reflecting abnormal synaptic transmission. While retinal vasculature was unaffected, TGFBR2-deficient microglia demonstrated exaggerated responses to laser-induced injury that was associated with increased choroidal neovascularization, a hallmark of advanced exudative AMD. These findings demonstrate that deficiencies in TGFβ-mediated microglial regulation can drive neuroinflammatory contributions to AMD-related neurodegeneration and neovascularization, highlighting TGFβ signaling as a potential therapeutic target.
New Microfluidic-Based Sampling Procedure for Overcoming the Hematocrit Problem Associated with Dried Blood Spot Analysis (2015)

Hematocrit (Hct) is one of the most critical issues associated with the bioanalytical methods used for dried blood spot (DBS) sample analysis. Because Hct determines the viscosity of blood, it may affect the spreading of blood onto the filter paper. Hence, accurate quantitative data can only be obtained if the size of the paper filter extracted contains a fixed blood volume. We describe for the first time a microfluidic-based sampling procedure to enable accurate blood volume collection on commercially available DBS cards. The system allows the collection of a controlled volume of blood (e.g., 5 or 10 μL) within several seconds. Reproducibility of the sampling volume was examined in vivo on capillary blood by quantifying caffeine and paraxanthine on 5 different extracted DBS spots at two different time points and in vitro with a test compound, Mavoglurant, on 10 different spots at two Hct levels. Entire spots were extracted. In addition, the accuracy and precision (n = 3) data for the Mavoglurant quantitation in blood with Hct levels between 26% and 62% were evaluated. The interspot precision data were below 9.0%, which was equivalent to that of a manually spotted volume with a pipet. No Hct effect was observed in the quantitative results obtained for Hct levels from 26% to 62%. These data indicate that our microfluidic-based sampling procedure is accurate and precise and that the analysis of Mavoglurant is not affected by the Hct values. This provides a simple procedure for DBS sampling with a fixed volume of capillary blood, which could eliminate the recurrent Hct issue linked to DBS sample analysis.
Interaction between Pullulanase from Klebsiella pneumoniae and Cyclodextrins1 (1993)

The interaction between pullulanase from Klebsiella pneumoniae and alpha-, beta-, and gamma-cyclodextrins and 6-O-alpha-glucosyl-alpha-cyclodextrin and 6-O-alpha-glucosyl-beta-cyclodextrin was examined by means of inhibition studies of the enzyme activity, UV difference spectroscopy, and flow calorimetry. All the above cyclodextrins were found to be competitive inhibitors, but beta-cyclodextrin and 6-O-alpha-glucosyl-beta-cyclodextrin showed strong inhibition, the inhibitor constants being two orders of magnitude less than those of alpha- and gamma-cyclodextrins. The difference spectra of beta-cyclodextrin were slightly but significantly different from those of the other cyclodextrins, showing blue shift of a few nanometers. Moreover, only beta-cyclodextrin has a positive entropy change upon binding with the enzyme; all the other cyclodextrins have negative values. These results show that the binding mode of beta-cyclodextrin is subtly different from those of alpha- and gamma-cyclodextrins.
Quantification of Viscoelastic Effects of Polyacrylamide Solutions (1984)

Abstract Beyond a critical rate of flow in cores the viscoelasticity of polyacrylamide solutions is reflected by shear thickening behaviour. Practical information is provided on the critical flow rate and magnitude of shear thickening and their dependency on core permeability, temperature, molecular weight and concentration of commercial polymers. To describe the onset of shear thickening, critical Deborah numbers were calculated using fluid relaxation times obtained by oscillation rheometry. Using three core-flow parameters, viz. the critical flow rate and two power-law exponents, the viscoelastic effects are quantified.
Anterior segment uses of bevacizumab (2012)

Effective short-term response together with high patient tolerance to local bevacizumab therapy offer encouraging results for the management of anterior segment neovascular disorders. Although statistically significant regression of vessels has been documented in many studies, the clinical significance of this finding is still a subject of debate.
Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways (2005)

IkappaBalpha is an inhibitor of the nuclear transcription factor NF-kappaB. Binding of IkappaBalpha to NF-kappaB inactivates the transcriptional activity of NF-kappaB. Expression of IkappaBalpha itself is regulated by NF-kappaB, which provides auto-regulation of this signaling pathway. Here we present a mouse model for monitoring in vivo IkappaBalpha expression by imaging IkappaBalpha-luc transgenic mice for IkappaBalpha promoter driven luciferase activity. We demonstrated a rapid and systemic induction of IkappaBalpha expression in the transgenic mice following treatment with LPS. The induction was high in liver, spleen, lung and intestine and lower in the kidney, heart and brain. The luciferase induction in the liver correlated with increased IkappaBalpha mRNA level. Pre-treatment with proteasome inhibitor bortezomib dramatically suppressed LPS-induced luciferase activity. The p38 kinase inhibitor SB203580 also showed moderate inhibition of LPS-induced luciferase activity. Analysis of IkappaBalpha mRNA in the liver tissue showed a surprising increase of the IkappaBalpha mRNA after bortezomib and SB203580 treatments, which could be due to increased IkappaBalpha mRNA stability. Our data demonstrate that regulation of IkappaBalpha expression involves both the NF-kappaB and the p38 signaling pathways. The IkappaBalpha-luc transgenic mice are useful for analyzing IkappaBalpha expression and the NF-kappaB transcriptional activity in vivo.
A New Upscaling Method of Relative Permeability Curves for Reservoir Simulation (2009)

Abstract Relative permeability is one of the most important factors in numerical reservoir simulation. Although the relative permeability curves may be available on a very fine level of detail, their direct use to estimate the amount of uncertainty, which requires thousands of reservoir simulation runs, is generally not practical because of the excessive computer time and memory that would be required. Despite the extensive research that has been performed in the past few decades, effective upscaling to reduce computation times in highly heterogeneous reservoir still remains a challenging procedure. In this paper, we demonstrate how conventional upscaling approaches may lead to large errors. To overcome the inaccuracy, we investigated and developed a new relative permeability upscaling technique for the coarse scale modeling for heterogeneous reservoirs. In our new method, single-phase upscaling was applied at the beginning to set up the base case for optimization. The regression runs were conducted by non-linear optimization. The decision variables in a standard Corey and logistic form were used to check the errors between the coarse and fine models. After the procedure converged, a new relative permeability curve for the coarse model was generated. The match for the breakthrough time and post-breakthrough performance was very accurate using the new relative permeability curves. Predictability with the new curves also appeared to be substantially improved; the newly generated relative permeability curves can be used over periods beyond that of the original match. The new method was verified by using three-phase, 3D, and highly heterogeneous reservoir models. These verifications were performed on large models approaching one million cells with black oil and composition fluids with waterflooding and water-alternating-gas (WAG) recovery processes. The ultimate goal of the work has been to use the upscaled models with modified relative permeabilities to investigate how uncertainty is affected by upscaling. The fine scale results indicate that more reasonable results can be obtained for estimating the effect of uncertainty with the new upscaling technique as compared to conventional methods, with computation time orders of magnitude faster than previously available.
The role of an extracellular polysaccharide produced by the marine <i>Pseudomonas</i> sp. S9 in cellular detachment during starvation (1989)

An exopolysaccharide polymer is produced by the marine Pseudomonas sp. S9 in response to complete energy and nutrient starvation. The presence of this polysaccharide on the cell surface and its subsequent release have been shown to be associated with both adhesion and detachment of the bacterial cells. Detachment from a hydrophobic surface was correlated to the presence of the exopolysaccharide on detached S9 cells. The exopolysaccharide was detected, using immunofluorescence microscopy, on surface-bound cells after only 15 min of exogenous energy and nutrient deprivation. This technique did not reveal any significant amounts of exopolysaccharide on starving bulk phase cells prior to 3 h of starvation. Cells that detached after 5.5 h of starvation had low cell surface hydrophobicity values and increased amounts of cell-bound exopolysaccharide. In contrast, cells that became detached during the first 5.5 h of starvation showed increasing hydrophobicity values during prolonged bulk phase starvation.
Inhibition of Transforming Growth Factor-Activated Kinase 1 (TAK1) Blocks and Reverses Epithelial to Mesenchymal Transition of Mesothelial Cells (2012)

Peritoneal fibrosis is a frequent complication of peritoneal dialysis following repeated low grade inflammatory and pro-fibrotic insults. This pathological process may lead to ultrafiltration failure and eventually to the discontinuing of the therapy. Fibrosis is linked to epithelial to mesenchymal transition (EMT) of the peritoneal mesothelial cells, which acquire invasive and fibrogenic abilities. Here, we analyzed the role of the transforming growth factor-activated kinase-1 (TAK1) in the EMT of primary mesothelial cells from human peritoneum. The inhibition of TAK1 in mesenchymal-like mesothelial cells from the effluents of patients undergoing peritoneal dialysis led to the reacquisition of the apical to basolateral polarity, to increased expression of epithelial and to down-regulation of mesenchymal markers. TAK1 inhibition also resulted in decreased migratory/invasive abilities of effluent-derived mesothelial cells. Simultaneous inhibition of ERK1/2 and TAK1 pathways did not lead to an additive effect in the reacquisition of the epithelial phenotype. Inhibition of TAK1 also blocked EMT in vitro and reduced the levels of PAI-1, which is involved in fibrosis and invasion. Analysis of signalling pathways downstream of TAK1 involved in EMT induction, showed that TAK1 inhibition reduced the transcriptional activity of NF-κB and Smad3, as well as the phosphorylation of c-jun, while enhancing Smad1-5-8 activity. These results demonstrate that TAK1 is a cross-point in a network including different pro-EMT transcription factors, such as NF-κB, Snail, AP-1 and Smads. The identification of TAK1 as a main biochemical mediator of EMT and fibrosis in mesothelial cells from human peritoneum and the study of signalling pathways induced by its activity may be relevant in the design of new therapies aimed to counteract peritoneal fibrosis.
Changes in Whisky while Maturing (1943)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChanges in Whisky while MaturingA. J. Liebmann and Maurice RosenblattCite this: Ind. Eng. Chem. 1943, 35, 9, 994–1002Publication Date (Print):September 1, 1943Publication History Published online1 May 2002Published inissue 1 September 1943https://pubs.acs.org/doi/10.1021/ie50405a013https://doi.org/10.1021/ie50405a013research-articleACS PublicationsRequest reuse permissionsArticle Views117Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
New Therapeutic Approaches to Treatment of Malignant Gliomas: Chemotherapy and Immunotherapy (1984)

Neurosurgery: Volume 31 - Issue - p 456-469 doi: 10.1093/neurosurgery/31.CN_suppl_1.456
Evaluation of the ATB 32 A system for identification of anaerobic bacteria isolated from clinical specimens (1990)

A new miniaturized 4-h method for the identification of anaerobic bacteria, ATB 32 A (API System SA, Montalieu Vercieu, France), was evaluated against conventional methods of identification. The evaluation was done by using 260 recent clinical isolates and 21 reference strains of anaerobic bacteria. All reference strains were correctly identified and did not figure in the detailed analysis. Of the 140 gram-negative bacilli, 90.6% of Bacteroides spp. and 95.5% of Fusobacterium spp. were correctly identified to the species level, with an additional 8.4% of the Bacteroides spp. being identified to the genus level. Clostridia were correctly identified in 85.9% of cases, with an additional 9.9% being identified to the genus level. Peptostreptococci were correctly identified in 91.6% of cases. The 4 strains of Actinomyces spp. were all identified correctly, as were 10 of the 11 strains of Propionibacterium spp. A total of 3.1% of strains were not identified by ATB 32 A, while for 1.9% of strains, completely false identifications were obtained. Estimation of the individual preformed enzyme results may pose problems, although these decrease with familiarity with the system. With certain enzyme profiles, additional testing was necessary to arrive at an identification; however, there was no requirement for gas-liquid chromatography. If certain additions are made to the data base and the difficulties of determination of organisms to the species level among the non-Bacteroides fragilis (sensu stricto) members of the B. fragilis group can be reduced, this system holds promise as a reliable standardized alternative for the identification of anaerobic bacteria in clinical laboratories.
Application of the innovation systems framework in North-South research (2002)

This paper discusses the evolution of a development assistance research programme in South Asia. The programme supports North-South collaboration in the area of crop post-harvest issues. A novelty of the programme is the way it commissioned policy research on institutional issues impinging on the success of the research projects it commissioned. Through this and other learning activities, the programme has evolved the underlying principles of its approach, recently giving much more emphasis to the role of partnerships and institutional contexts in the planning and execution of its work. Underpinning this has been an exploration and application of the innovation systems framework. Lessons include the need to see North-South research collaboration in terms of its capacity development effects on national systems of partners and processes concerned with the development and use of innovations. Development assistance agencies should pay attention to the importance of engaging in their own institutional learning if they want to make more effective contributions to sustainable development through North-South research partnerships.
Computing the mind: how the mind really works (2009)

Preface I. Foundations 1. Brains, Minds, and Numbers 2. Computing Minds 3. Computing Brains 4. The Astonishing Hypothesis II. Faculties 5. Perception 6. Memory 7. Language 8. Thinking III. Finale 9. Being No One 10. Imagine 11. The Mind in the Act of Finding Appendices A. Bayesian Inference and Decision Making B. Mind the Gap Bibliography Index Credits