gebhart/patrepeval huggingface dataset:
Aluminum Burn Rate Modifiers Based on Reactive Nanocomposite Powders (2010)

Abstract Aluminum powders have long been used as additives in propellants, pyrotechnics, and explosives. Aluminum has a high enthalpy of combustion but relatively low burn rate. Addition of reactive nanocomposite powders can increase the burn rate of aluminum and thus the overall reaction rate of the energetic formulation. Replacing only a small fraction of the fuel by a nanocomposite material can enhance the reaction rate with little change to the thermodynamic performance of the formulation. This research showed the feasibility of the above concept using nanocomposite powders prepared by arrested reactive milling (ARM), a scalable “top‐down” technique for manufacturing reactive nanomaterials. The nanocomposite materials used in this study were 2B+Ti, and Al‐rich thermites: 8Al+3CuO, and 8Al+MoO 3 . The reactive nanocomposite powders were added to micrometer‐sized aluminum powder and the mixture was aerosolized and burned in a constant volume chamber. The combustion atmosphere was varied using oxygen, nitrogen, and methane. The resulting pressure traces were recorded and processed to compare different types and amounts of modifiers. Additives of nanocomposite powders of 8Al+MoO 3 and 2B+Ti to micrometer‐sized aluminum were found to be effective in increasing both the rate of pressure rise and maximum pressure in the respective constant volume explosion experiments. It was observed that 20 wt.‐% of additive resulted in the best combination of the achieved burn rate and pressure.
Improved music feature learning with deep neural networks (2014)

Recent advances in neural network training provide a way to efficiently learn representations from raw data. Good representations are an important requirement for Music Information Retrieval (MIR) tasks to be performed successfully. However, a major problem with neural networks is that training time becomes prohibitive for very large datasets and the learning algorithm can get stuck in local minima for very deep and wide network architectures. In this paper we examine 3 ways to improve feature learning for audio data using neural networks: 1.using Rectified Linear Units (ReLUs) instead of standard sigmoid units; 2.using a powerful regularisation technique called Dropout; 3.using Hessian-Free (HF) optimisation to improve training of sigmoid nets. We show that these methods provide significant improvements in training time and the features learnt are better than state of the art handcrafted features, with a genre classification accuracy of 83 ± 1.1% on the Tzanetakis (GTZAN) dataset. We found that the rectifier networks learnt better features than the sigmoid networks. We also demonstrate the capacity of the features to capture relevant information from audio data by applying them to genre classification on the ISMIR 2004 dataset.
AQP3, p-AQP2, and AQP2 expression is reduced in polyuric rats with hypercalcemia: prevention by cAMP-PDE inhibitors (2002)

The purpose of this study was to evaluate whether hypercalcemia is associated with downregulation of renal aquaporins (AQPs), including AQP1, AQP2, phosphorylated AQP2 (p-AQP2), AQP3, and AQP4, and if this is the case, to test whether cAMP-phosphodiesterase (PDE) inhibitor treatment can prevent AQP downregulation and prevent the development of polyuria. Vitamin D-induced hypercalcemia in rats was associated with increased urine output and reduced urine osmolality, consistent with previous findings (Levi M, Peterson L, and Berl T. Kidney Int 23: 489-497, 1983). Semiquantitative immunoblotting revealed a significant reduction in the abundance of inner medullary AQP2 (52 +/- 6% of control levels), consistent with previous studies, and of AQP2, which is phosphorylated at the PKA phosphorylation consensus site serine 256 (p-AQP2; 36 +/- 8%). Moreover, AQP3 abundance was also significantly decreased (45 +/- 7 and 61 +/- 6% of control levels in inner medulla and whole kidney, respectively). Consistent with this, immunohistochemistry demonstrated reduced AQP3 immunolabeling along the entire collecting duct. AQP4 expression was not reduced. Surprisingly, total kidney AQP1 abundance was also reduced (60 +/- 6%). AQP1 expression was reduced in the cortex and outer stripe of the outer medulla (48 +/- 7%; i.e., in proximal tubules). In contrast, AQP1 levels were not changed in the inner stripe of the outer medulla or in the inner medulla (i.e., descending thin limbs and vasa recta). Treatment with the cAMP-PDE inhibitors rolipram and milrinone in combination (inhibiting PDE IV and PDE III isoenzymes) at day 2 and onward completely prevented the hypercalcemia-induced downregulation of AQP2 and AQP3 (but not AQP1) and completely prevented the development of polyuria. In conclusion, AQP3, AQP2, and p-AQP2 are downregulated and are likely to play critical roles in the development of polyuria associated with vitamin D-induced hypercalcemia. Moreover, PDE inhibitor treatment significantly prevented the reduced expression of collecting duct AQPs and prevented the development of polyuria.
Stimulatory Effect of Cyanidin 3-Glycosides on the Regeneration of Rhodopsin (2003)

Anthocyanins have been suggested to improve visual functions. This study examined the effect of four anthocyanins in black currant fruits on the regeneration of rhodopsin using frog rod outer segment (ROS) membranes. Cyanidin 3-glycosides, glucoside and rutinoside, stimulated the regeneration, but the corresponding delphinidins showed no significant effect. The formation of a regeneration intermediate was suggested to be accelerated by cyanidin 3-rutinoside. Their effects on the cGMP-phosphodiesterase activity in the ROS membranes were also investigated but found to be negligible. It was concluded that the major effect of anthocyanins in rod photoreceptors is on the regeneration of rhodopsin.
Conversion of biomass platform molecules into fuel additives and liquid hydrocarbon fuels (2013)

In this work some relevant processes for the preparation of liquid hydrocarbon fuels and fuel additives from cellulose, hemicellulose and triglycerides derived platform molecules are discussed. Thus, it is shown that a series of platform molecules such as levulinic acid, furans, fatty acids and polyols can be converted into a variety of fuel additives through catalytic transformations that include reduction, esterification, etherification, and acetalization reactions. Moreover, we will show that liquid hydrocarbon fuels can be obtained by combining oxygen removal processes (e.g. dehydration, hydrogenolysis, hydrogenation, decarbonylation/descarboxylation etc.) with the adjustment of the molecular weight via C–C coupling reactions (e.g. aldol condensation, hydroxyalkylation, oligomerization, ketonization) of the reactive platform molecules.
High density GaN/AlN quantum dots for deep UV LED with high quantum efficiency and temperature stability (2014)

High internal efficiency and high temperature stability ultraviolet (UV) light-emitting diodes (LEDs) at 308 nm were achieved using high density (2.5 × 10(9) cm(-2)) GaN/AlN quantum dots (QDs) grown by MOVPE. Photoluminescence shows the characteristic behaviors of QDs: nearly constant linewidth and emission energy, and linear dependence of the intensity with varying excitation power. More significantly, the radiative recombination was found to dominant from 15 to 300 K, with a high internal quantum efficiency of 62% even at room temperature.
Test and evaluate passive orbital disconnect struts (PODS 3) (1985)

The objectives of the Passive Orbital Disconnect Struts (PODS) test are to evaluate modal resonance of the PODS-III supports to obtain engineering data required for use of PODS-III on flight systems; determine possible performance improvements in large LO2/LH2 space applications. (1) Modal Vibration Tests. A modal resonance survey is performed on a set of six PODS-III struts assembled in a dewar simulator. The survey conditions simulate both launch and orbital loadings of the struts. The orbital load range spans a full to an empty tank. The frequencies surveyed cover the range consistent with Shuttle qualification requirements and the principal resonant modes of the strut system. (2) Benefit study. The benefit of using PODS-III supports on OTV and Space Station LO sub 2 and LH sub 2 reference tanks was compared to nondisconnect supports. Four LO sub 2 and LH sub 2 tanks were studied under various conditions: (1) holding the launch resonance at 35 Hz and varying the orbit resonance; (2) analyzing both full and emtpy tanks at launch; (3) varying orbit boundary temperaure; (4) varying the number of struts; (5) varying orbit times; and (6) using or not using vapor cooling.
Improving the accuracy of pronunciation prediction for unit selection TTS (2003)

This paper describes a technique which improves the accuracy of pronunciation prediction for unit selection TTS. It does this by performing an orthography-based context-dependent lookup on the unit database. During synthesis, the pronunciations of words which have matching contexts in the unit database are determined. Pronunciations not found using this method are determined using traditional lexicon lookup and/or letter-to-sound rules. In its simplest form, the model involves a lookup based on left and right word context. A modified form, which backsoff to a lookup based on right context, is shown to have a much higher firing rate, and to produce more pronunciation variation. The technique is good at occasionally inhibiting vowel reduction; at choosing appropriate pronunciations in case of free variation; and at choosing the correct pronunciation for names. Its effectiveness is assessed by experiments on unseen data; by resynthesis; and by a listening test on sentences rich in reducible words.
Cylindrical Bragg fibers: A design and feasibility study for optical communications (1983)

The possible use of Bragg fibers for long-distance low-loss optical communications is investigated, structures calculated, and their limitations established. It is found that the original design of Bragg fibers offers no possibility of low-loss propagation.
ChemInform Abstract: Formation and Destruction of Diazine Ring under Conditions of the Vilsmeier—Haack Formylation of 4‐Dialkylaminonaphthalic Acid Derivatives. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Cyclic GMP-dependent protein kinase stimulates the plasma membrane Ca2+ pump ATPase of vascular smooth muscle via phosphorylation of a 240-kDa protein. (1991)

The plasma membrane Ca2+ pump ATPase from porcine aorta was isolated by the calmodulin affinity chromatographic method of Kosk-Kosicka et al. (Kosk-Kosicka, D., Scaillet, S., and Inesi, G. (1986) J. Biol. Chem. 261, 3333-3338). Its activity was restored by adding either phosphatidylcholine or phosphatidylserine. Cyclic GMP-dependent protein kinase (G-kinase) stimulated the enzyme in a concentration-dependent manner. However, phosphatidylinositol kinase (PI-kinase) activity was not detected in the enzyme preparation, and the presence of phosphatidylinositol was not necessary for stimulation by G-kinase. Furthermore, adenosine, a potent PI-kinase inhibitor, did not affect the stimulation. The enzyme preparation contained three major proteins, with molecular masses of 240, 145, and 135 kDa, as assessed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The 240- and 135-kDa proteins were phosphorylated in association with the stimulation by G-kinase, but only the phosphorylation of the 240-kDa protein was dependent on the G-kinase concentration. A purified enzyme without the 240-kDa protein, prepared by our previous method (Imai, S., Yoshida, Y., and Sun, H.-T. (1990) J. Biochem. (Tokyo) 107, 755-761), was not activated by G-kinase. Immunoblotting with an antibody against the human erythrocyte Ca2+ pump revealed that the 135-kDa protein corresponded to one of the isoforms of the plasma membrane Ca2+ pump. These results suggest that the phosphorylation of the 240-kDa protein is responsible for stimulation of the plasma membrane Ca2+ pump ATPase by G-kinase.
Context Adaptive Lagrange Multiplier (CALM) for Rate-Distortion Optimal Motion Estimation in Video Coding (2010)

In this paper, we propose an efficient and practical algorithm to dynamically adapt the Lagrange multipliers for each macroblock based on the context of the neighboring or upper layer blocks to improve rate-distortion performance. Our method improves the accuracy for the detection of true motion vectors as well as the most efficient encoding modes for luma, which are used for deriving the motion vectors, and modes for chroma. Simulation results for H.264/advanced video coding video demonstrate that our method reduces bit rate significantly and achieves peak signal-to-noise ratio gain over those of the joint model (JM) software for all sequences tested, with negligible extra computational cost. The improvement is particularly significant for high motion high-resolution videos. This paper describes our work that led to our Joint Video Team adopted contribution (included in software JM 12.0 onward), collectively known as context adaptive Lagrange multiplier (CALM).
Structural Trends in the Aging Femoral Neck and Proximal Shaft: Analysis of the Third National Health and Nutrition Examination Survey Dual-Energy X-Ray Absorptiometry Data (2000)

Hip scans of U.S. adults aged 20-99 years acquired in the Third National Health and Nutrition Examination Survey (NHANES III) using dual-energy X-ray absorptiometry (DXA) were analyzed with a structural analysis program. The program analyzes narrow (3 mm wide) regions at specific locations across the proximal femur to measure bone mineral density (BMD) as well as cross-sectional areas (CSAs), cross-sectional moments of inertia (CSMI), section moduli, subperiosteal widths, and estimated mean cortical thickness. Measurements are reported here on a non-Hispanic white subgroup of 2,719 men and 2,904 women for a cortical region across the proximal shaft 2 cm distal to the lesser trochanter and a mixed cortical/trabecular region across the narrowest point of the femoral neck. Apparent age trends in BMD and section modulus were studied for both regions by sex after correction for body weight. The BMD decline with age in the narrow neck was similar to that seen in the Hologic neck region; BMD in the shaft also declined, although at a slower rate. A different pattern was seen for section modulus; furthermore, this pattern depended on sex. Specifically, the section modulus at both the narrow neck and the shaft regions remains nearly constant until the fifth decade in females and then declined at a slower rate than BMD. In males, the narrow neck section modulus declined modestly until the fifth decade and then remained nearly constant whereas the shaft section modulus was static until the fifth decade and then increased steadily. The apparent mechanism for the discord between BMD and section modulus is a linear expansion in subperiosteal diameter in both sexes and in both regions, which tends to mechanically offset net loss of medullary bone mass. These results suggest that aging loss of bone mass in the hip does not necessarily mean reduced mechanical strength. Femoral neck section moduli in the elderly are on the average within 14% of young values in females and within 6% in males.
Gate Decisions: The Key to Managing Risk during New Product Development (2004)

This chapter contains sections titled: Introduction Gates Types and Their Components Why Are Good Gate Decisions Vital? Improving Gate Decisions Summary References
Low Variance Adaptive Filter for Cancelling Motion Artifact in Wearable Photoplethysmogram Sensor Signals (2007)

The photoplethysmogram (PPG) is an extremely useful wearable sensing medical diagnostic tool. However, the PPG signal becomes highly corrupted and unusable when the sensor wearer is in motion. This paper investigates how confidently Widrow's Adaptive Noise Cancellation can eliminate motion artifact and recover a motion corrupted PPG signal for a wearer engaged in jogging motions. It has previously been shown that Widrow's Adaptive Noise Cancellation can recover a motion corrupted PPG signal for certain data sets by using a collocated accelerometer to measure the corrupting motion. However, wearer motion is band limited, and provides little information for estimating motion-to-PPG noise transfer dynamics. This means that, without proper care, recovery results can be unreliable. In the present work, both Finite Impulse Response (FIR) and Laguerre series black box transfer dynamics models are evaluated for how confidently they can be identified. Model confidence is quantified in terms of variance of the transfer dynamics estimate at the motion frequencies. For typical jogging motion, it is found that standard deviation of the FIR model transfer dynamics is 30% of the mean value at the motion input frequency. The standard deviation of the Laguerre model transfer dynamics is only 1%. Time domain data shows how a Laguerre model outperforms a FIR model in accordance with the computed model variance.
Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris (2012)

Pemphigus vulgaris (PV) is an autoimmune blistering skin disease characterized by suprabasal acantholysis and by autoantibodies against desmoglein 3 localized on desmosomes. In addition, caspases also seem to participate in this blistering disease. Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase involved in cytoskeleton remodelling and formation and disassembly of cell adhesion structures. We have previously demonstrated that HER (human epidermal growth factor receptor related) isoforms, Src (Rous sarcoma) and mammalian target of rapamycin (mTOR), three molecules implicated in signalling processes, take part in suprabasal acantholysis and apoptosis induced by PV-IgG in a mouse model. Our aim was to investigate whether upregulation of FAK is implicated in the development of PV lesions. Herein, using a mouse model, PV-IgG administration showed an increased level of FAK phosphorylated on 397 and 925 tyrosine residues in the basal layer of epidermis. When mice were pretreated with a FAK inhibitor (FI), the acantholysis of the basal layer of epidermis was absent. More interestingly, we observed that phosphorylated FAK (Y397/925) decreased when HER isoforms, Src, mTOR and pan-caspases inhibitors were employed before PV-IgG administration. In addition, pretreatment with the FI before PV-IgG injection prevented the changes in both Bax and Bcl-2 expression and caspase-9 and caspase-3 activities induced by PV-IgG. Finally, FI reduced the expression of phosphorylated Src and mTOR in the basal cells of epidermis. In conclusion, our data reveal a novel role of phosphorylated FAK (Y397/925) in PV development involving HER isoforms, Src and mTOR kinases.
Construction of a Prophage-Free Variant of Corynebacterium glutamicum ATCC 13032 for Use as a Platform Strain for Basic Research and Industrial Biotechnology (2013)

The activity of bacteriophages and phage-related mobile elements is a major source for genome rearrangements and genetic instability of their bacterial hosts. The genome of the industrial amino acid producer Corynebacterium glutamicum ATCC 13032 contains three prophages (CGP1, CGP2, and CGP3) of so far unknown functionality. Several phage genes are regularly expressed, and the large prophage CGP3 (∼190 kbp) has recently been shown to be induced under certain stress conditions. Here, we present the construction of MB001, a prophage-free variant of C. glutamicum ATCC 13032 with a 6% reduced genome. This strain does not show any unfavorable properties during extensive phenotypic characterization under various standard and stress conditions. As expected, we observed improved growth and fitness of MB001 under SOS-response-inducing conditions that trigger CGP3 induction in the wild-type strain. Further studies revealed that MB001 has a significantly increased transformation efficiency and produced about 30% more of the heterologous model protein enhanced yellow fluorescent protein (eYFP), presumably as a consequence of an increased plasmid copy number. These effects were attributed to the loss of the restriction-modification system (cg1996-cg1998) located within CGP3. The deletion of the prophages without any negative effect results in a novel platform strain for metabolic engineering and represents a useful step toward the construction of a C. glutamicum chassis genome of strain ATCC 13032 for biotechnological applications and synthetic biology.
Tilted cone-beam reconstruction with row-wise fan-to-parallel rebinning (2006)

Reconstruction algorithms for cone-beam CT have been the focus of many studies. Several exact and approximate reconstruction algorithms were proposed for step-and-shoot and helical scanning trajectories to combat cone-beam related artefacts. In this paper, we present a new closed-form cone-beam reconstruction formula for tilted gantry data acquisition. Although several algorithms were proposed in the past to combat errors induced by the gantry tilt, none of the algorithms addresses the scenario in which the cone-beam geometry is first rebinned to a set of parallel beams prior to the filtered backprojection. We show that the image quality advantages of the rebinned parallel-beam reconstruction are significant, which makes the development of such an algorithm necessary. Because of the rebinning process, the reconstruction algorithm becomes more complex and the amount of iso-centre adjustment depends not only on the projection and tilt angles, but also on the reconstructed pixel location. In this paper, we first demonstrate the advantages of the row-wise fan-to-parallel rebinning and derive a closed-form solution for the reconstruction algorithm for the step-and-shoot and constant-pitch helical scans. The proposed algorithm requires the 'warping' of the reconstruction matrix on a view-by-view basis prior to the backprojection step. We further extend the algorithm to the variable-pitch helical scans in which the patient table travels at non-constant speeds. The algorithm was tested extensively on both the 16- and 64-slice CT scanners. The efficacy of the algorithm is clearly demonstrated by multiple experiments.
Nonlinear dynamics induced anomalous Hall effect in topological insulators (2016)

We uncover an alternative mechanism for anomalous Hall effect. In particular, we investigate the magnetisation dynamics of an insulating ferromagnet (FM) deposited on the surface of a three-dimensional topological insulator (TI), subject to an external voltage. The spin-polarised current on the TI surface induces a spin-transfer torque on the magnetisation of the top FM while its dynamics can change the transmission probability of the surface electrons through the exchange coupling and hence the current. We find a host of nonlinear dynamical behaviors including multistability, chaos, and phase synchronisation. Strikingly, a dynamics mediated Hall-like current can arise, which exhibits a nontrivial dependence on the channel conductance. We develop a physical understanding of the mechanism that leads to the anomalous Hall effect. The nonlinear dynamical origin of the effect stipulates that a rich variety of final states exist, implying that the associated Hall current can be controlled to yield desirable behaviors. The phenomenon can find applications in Dirac-material based spintronics.