gebhart/patrepeval huggingface dataset:
Converters dedicated to long-term monitoring of strain gauge transducers (1997)

This paper presents two new strain gauge bridge-to-pulse position modulation (PPM) converters. They have been developed in 2-/spl mu/m BiCMOS technology. The first one uses a chopper amplifier and a voltage-to-time converter associated in a feedback loop. This topology mainly exhibits an automatic offset cancellation capability, a ratiometric transfer function, and 10-b accuracy. The second one is a voltage-to-frequency converter using the switched-capacitor (SC) technique. It is an optimized version in terms of size minimization and noise rejection. Furthermore, a special RF transmitter has been designed in order to send the data from an intracorporal sensing and conditioning circuitry to an external computer dedicated to data analysis. Moreover, these converters are insensitive to offset drifts and are well suited for long term monitoring of orthopedic implants used for the treatment of bone fractures.
LASIK and dry eye. (2007)

Dry eye is one of the most common complications after laser-assisted in situ keratomileusis (LASIK). The clinical signs of post-LASIK dry eye include positive vital staining of ocular surface, decreased tear film breakup time and Schirmer test, reduced corneal sensitivity, and decreased functional visual acuity. The symptoms and signs last at least 1 month after LASIK. Although the mechanisms for developing post-LASIK dry eye are not completely understood, loss of corneal innervation by flap-making may affect the reflex loops of the corneal-lacrimal gland, corneal-blinking, and blinking-meibomian gland, and blinking-meibomian gland, resulting in decreased aqueous and lipid tear secretion and mucin expression. As LASIK enhancement by flap-lifting induces less dry eye symptoms and signs than first surgery, it is suggested that other factors rather than loss of neurotrophic effect may be involved in the mechanisms of post-LASIK dry eye. The treatments of dry eye include artificial tears, topical cyclosporine, hot compress, punctal plugs, and autologous serum eye drops. For patients with severe preoperative dry eye, a combination of punctal plugs and serum eye drops is required to be used before surgery.
Rapid room temperature syntheses of zeolitic-imidazolate framework (ZIF) nanocrystals (2014)

Here we report a simple solvent mixture controlled rapid room temperature syntheses for facile access to uniform zeolitic-imidazolate framework (ZIF) nanocrystals.
Series and parallel operation of the emitter turn-off (ETO) thyristor (2002)

By dramatically decreasing the storage time, the emitter turn-off (ETO) thyristors have a very good match in storage time. Storage time dispersion of less than /spl plusmn/100 nsec is normal for ETOs and can be further reduced through adjustment of the emitter switch gate resistance. Thus, the capacitance required for dynamic voltage balancing in the ETO series connection is significantly reduced. Uniform current sharing for parallel connected ETO is also guaranteed at the device level through the open-base PNP turn-off mechanism. The current balancing inductance can be essentially removed. Theoretical analysis and experimental results of 53 mm ETOs are presented.
Path Grammar Guided Trace Compression and Trace Approximation (2006)

Trace-driven simulation is an important technique used in the evaluation of computer architecture innovations. However using it for studying parallel computers and applications is at best very challenging. Acquiring, representing and storing the traces are among the major issues. In this paper, we introduce path grammar guided trace compression (PGGTC) and effective address trace approximation (TA) to speedup compression and reduce trace sizes. PGGTC relies on static analysis to build rules and determine actions to guide online trace compression. Combined with gzip, PGGTC can compresses control flow traces over 330 times smaller than using gzip alone. Compared to the widely popular Sequitur algorithm alone, PGGTC with gzip is on average 40 times faster, while the traces are only 3 times bigger. PGGTC can be also used with Sequitur to double the compression ratios of Sequitur by itself and do it 14 times faster than Sequitur by itself. Address traces of parallel applications with significant randomness are often impossibly large even after being compressed with any lossless scheme including PGGTC. For effective address trace reduction, we introduce trace approximation (TA). Performance-wise similar effective addresses are generated based on very compact summaries of how the memory is accessed during each structure instance instead of compressing them. We demonstrate two approaches: selective dumping and memory signatures, to summarize the properties of effective address sequences. Both approaches are validated by feeding the generated approximate trace to cache simulators of 25 different configurations. The simulated results are very close to the simulation results based on full effective traces while the selective dumped address or memory signatures require several order of magnitude less disk space to store. In summary, we move trace-driven simulation into the realm of the feasible for larger parallel machines and applications
Crystal structure of YbaK protein fromHaemophilus influenzae (HI1434) at 1.8 ? resolution: Functional implications (2000)

Structural genomics of proteins of unknown function most straightforwardly assists with assignment of biochemical activity when the new structure resembles that of proteins whose functions are known. When a new fold is revealed, the universe of known folds is enriched, and once the function is determined by other means, novel structure-function relationships are established. The previously unannotated protein HI1434 from H. influenzae provides a hybrid example of these two paradigms. It is a member of a microbial protein family, labeled in SwissProt as YbaK and ebsC. The crystal structure at 1.8 A resolution reported here reveals a fold that is only remotely related to the C-lectin fold, in particular to endostatin, and thus is not sufficiently similar to imply that YbaK proteins are saccharide binding proteins. However, a crevice that may accommodate a small ligand is evident. The putative binding site contains only one invariant residue, Lys46, which carries a functional group that could play a role in catalysis, indicating that YbaK is probably not an enzyme. Detailed sequence analysis, including a number of newly sequenced microbial organisms, highlights sequence homology to an insertion domain in prolyl-tRNA synthetases (proRS) from prokaryote, a domain whose function is unknown. A HI1434-based model of the insertion domain shows that it should also contain the putative binding site. Being part of a tRNA synthetases, the insertion domain is likely to be involved in oligonucleotide binding, with possible roles in recognition/discrimination or editing of prolyl-tRNA. By analogy, YbaK may also play a role in nucleotide or oligonucleotide binding, the nature of which is yet to be determined.
Pattern of Asymmetry of Paraspinal Muscle Size in Adolescent Idiopathic Scoliosis Examined by Real-Time Ultrasound Imaging (1993)

The symmetry of lumbar multifidus size was examined in 20 patients with adolescent idiopathic scoliosis, aged 12-19 years. With the subject prone, bilateral real-time ultrasound images were obtained at the level of the 4th lumbar vertebra. Cross-sectional area and linear (horizontal and vertical) measurements were made using on-screen calipers. A pattern of asymmetry of lumbar multifidus cross-sectional area was shown to exist for the different curve types. The cross-sectional area was smaller (P < 0.0001) on the opposite side to the convexity of a primary thoracic curve, and on the convex side of a lumbar or thoracolumbar curve. The combined linear measurements (multiplied) correlated with cross-sectional area (r = 0.95) and could therefore be used for rapid clinical assessment of multifidus size. These preliminary findings provide a basis for further investigation of the role of the musculature in the pathogenesis of adolescent idiopathic scoliosis.
Photoresponsive, switchable, pressure-sensitive adhesives: influence of UV intensity and hydrocarbon chain length of low molecular weight azobenzene compounds (2021)

Unlike traditional adhesives with a fixed adhesive force, switchable adhesives, which have an adhesive force that can be adjusted by external stimuli, are specifically designed to be released according to user demand, or to enable the transfer of fine electronic devices. Previously developed switchable adhesives have limitations such as a slow switching rate, narrow adhesion modulation range, or the lack of reusability. Thus, we fabricated switchable pressure-sensitive adhesives (PSAs) that can overcome these limitations. The adhesive force of each switchable PSA, which comprises an azobenzene-containing acrylic polymer and low molecular weight compounds, was designed to be activated/deactivated <i>via</i> ultraviolet (UV) and visible light irradiation. The adhesive force and UV intensity required for the switch were found to be dependent on the aliphatic chain length of the compound. The adhesive force of the SP-C10, <i>i.e.</i>, a switchable PSA containing a azobenzene compound with an aliphatic chain of 10 hydrocarbons, increased to 3.5 N from nearly zero in response to only 30 s of low-level (25 mW cm<sup>-2</sup>) UV irradiation. Additionally, SP-C10 did not lose its adhesive force even after 30 cycles of repeated adhesion switching. The mechanism of adhesion switching influenced by UV intensity and the structure of low molecular weight azobenzene compounds are also reported.
논문 : 친환경 철도의 노선 선정을 위한 환경생태적 적합성 평가 연구 (2012)

(연구배경 및 목적)70년대 이후 경제적인 발전을 도모하기 위한 노력 중 하나가 도로 및 철도건설인데 이로 인해 생태계의 단절과 습지 및 서식처의 파괴가 빈번하게 일어나게 되어 동·식물들의 입지를 좁혀 나아가 인간에게까지 영향을 미치게 되었다. 하지만 최근에는 다양한 건설현장에서 생태 및 환경적 요소를 배려한 환경친화형 계획·설계 및 시공·관리 전략이 강조되고 있다. (연구방법)본 연구에서는 철도 및 도로의 노선선정에 관한 선행연구와 관련이론을 통해 철도 노선 선정단계에서의 고려사항을 선정하고 이를 호남고속철도 계룡산 통과구간에 적용하여 분석하였다. (결과) 결과, 호남고속철도가 연구구간내의 생태네트워크 주축과 부축을 통과하고 있음을 알 수 있었는데 교량과 터널로 이루어지는 예정노선으로 인해생태네트워크에 많은 영향을 끼치지 않을 것이라 예상되었지만 완공되기전 공사기간을 고려할 때 주변 생태계에 적지 않은 영향을 끼치게 될 것으로 판단된다.
Embedded Chip Build-Up Using Fine Line Interconnect (2007)

Advanced packaging technologies are driven by two generally balanced forces: performance advances being made by the semiconductor industry and the product requirements of the leading electronics markets. The semiconductor advancements include shrinking feature sizes and innovative transistor structures that provide ever more functionality per unit area of silicon and faster clock rates. One of the leading electronics markets is the portable electronics market, covering cell phones, digital assistants, portable entertainment and digital cameras. These products are driving smaller and thinner packages, finer featured substrates, multichip packages, such as SiPs (System-in-Packages) and 3-D stacking. They are also driving to mixed analog, digital, and RF circuitry within one package with increasing concerns with interconnect parasitics, EMI shielding and thermal performance. A new family of embedded chip packaging and interconnection approaches are being developed to address the next generation portable electronics circuits. These embedded chip approaches feature embedded actives and passives, micro-vias, thin film polymer dielectrics and fine line build-up interconnections. This paper will look at a number of embedded chip approaches including the GE Embedded Chip Build-Up technology and analyze the electrical, density, reliability and cost advantages of this approach and show examples of its use in chip scale, chip carrier, and SiP applications for portable electronics applications.
Wasp aids oriental fruit moth control (1948)

The infiltration of the Oriental fruit moth into California was discovered in the peach orchards of Orange County in 1942.
Automatic Metallic Surface Defect Detection and Recognition with Convolutional Neural Networks (2018)

Automatic metallic surface defect inspection has received increased attention in relation to the quality control of industrial products. Metallic defect detection is usually performed against complex industrial scenarios, presenting an interesting but challenging problem. Traditional methods are based on image processing or shallow machine learning techniques, but these can only detect defects under specific detection conditions, such as obvious defect contours with strong contrast and low noise, at certain scales, or under specific illumination conditions. This paper discusses the automatic detection of metallic defects with a twofold procedure that accurately localizes and classifies defects appearing in input images captured from real industrial environments. A novel cascaded autoencoder (CASAE) architecture is designed for segmenting and localizing defects. The cascading network transforms the input defect image into a pixel-wise prediction mask based on semantic segmentation. The defect regions of segmented results are classified into their specific classes via a compact convolutional neural network (CNN). Metallic defects under various conditions can be successfully detected using an industrial dataset. The experimental results demonstrate that this method meets the robustness and accuracy requirements for metallic defect detection. Meanwhile, it can also be extended to other detection applications.
Direct secretagogue effect of corticotropin-releasing factor on the rat adrenal cortex: the involvement of the zona medullaris (1992)

CRF dose-dependently enhanced corticosterone (B) secretion by rat adrenal slices including both cortex and medulla. Conversely, CRF did not exert any B response by fragments of adrenocortical autotransplants, which are completely deprived of chromaffin tissue. However, autotransplant quarters exhibited a dose-dependent response to ACTH qualitatively similar to that of adrenal slices, although markedly less intense. The maximal B response of adrenal slices to CRF (10(-8) M) was completely annulled by corticotropin-inhibiting peptide (10(-6) M), a competitive inhibitor of ACTH, which totally blocked the secretory response to ACTH (10(-8) M) of both kinds of preparations. ACTH immunoreactivity was present in the adrenal gland of control rats, but was undetectable in autotransplanted adrenocortical nodules. Moreover, adrenal fragments mainly composed of chromaffin tissue released detectable amounts of ACTH in response to high concentrations of CRF (10(-8)/10(-6) M). These findings suggest that chromaffin medullary cells play a pivotal role in the direct adrenocortical secretagogue effect of CRF, probably by releasing ACTH, which, in turn, may evoke, in a paracrine manner, the glucocorticoid response.
Neoplastic Transformation by Truncated Alleles of Human <i>NOTCH1/TAN1</i> and <i>NOTCH2</i> (1997)

The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during development. Although ligands for Notch proteins have been identified, the signaling cascade downstream of the receptors remains poorly understood. In human acute lymphoblastic T-cell leukemia, a chromosomal translocation damages the NOTCH1 gene. The damage apparently gives rise to a constitutively activated version of NOTCH protein. Here we show that a truncated version of NOTCH1 protein resembling that found in the leukemic cells can transform rat kidney cells in vitro. The transformation required cooperation with the E1A oncogene of adenovirus. The transforming version of NOTCH protein was located in the nucleus. In contrast, neither wild-type NOTCH protein nor a form of the truncated protein permanently anchored to the plasma membrane produced transformation in vitro. We conclude that constitutive activation of NOTCH similar to that found in human leukemia can contribute to neoplastic transformation. Transformation may require that the NOTCH protein be translocated to the nucleus. These results sustain a current view of how Notch transduces a signal from the surface of the cell to the nucleus.
Boundary-Element-Based Finite Element Methods For Helmholtz And Maxwell Equations On General Polyhedral Meshes (2009)

We present new finite element methods for Helmholtz and Maxwell equations on general three-dimensional polyhedral meshes, based on domain decomposition with boundary elements on the surfaces of the polyhedral volume elements. The methods use the lowest-order polynomial spaces and produce sparse, symmetric linear systems despite the use of boundary elements. Moreover, piecewise constant coefficients are admissible. The resulting approximation on the element surfaces can be extended throughout the domain via representation formulas. Numerical experiments confirm that the convergence behavior on tetrahedral meshes is comparable to that of standard finite element methods, and equally good performance is attained on more general meshes.
Protease Inhibitors Produced by<i>Streptomyces libani</i> (1979)

Journal Article Protease Inhibitors Produced by Streptomyces libani Get access Syuichi Oka, Syuichi Oka Fermentation Research Institute, Inage, Chiba-shi, Japan Search for other works by this author on: Oxford Academic Google Scholar Hideo Suzuki, Hideo Suzuki Fermentation Research Institute, Inage, Chiba-shi, Japan Search for other works by this author on: Oxford Academic Google Scholar Yoshiaki Hirata, Yoshiaki Hirata Central Research Laboratories, Takara Shuzo Co., Ltd., Otsushi, Shiga-ken, Japan Search for other works by this author on: Oxford Academic Google Scholar Osamu Tanabe Osamu Tanabe Central Research Laboratories, Takara Shuzo Co., Ltd., Otsushi, Shiga-ken, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 43, Issue 4, 1 April 1979, Pages 691–696, https://doi.org/10.1080/00021369.1979.10863534 Published: 01 April 1979 Article history Received: 31 May 1978 Published: 01 April 1979
Redox Proteomics of Protein-bound Methionine Oxidation (2011)

We here present a new method to measure the degree of protein-bound methionine sulfoxide formation at a proteome-wide scale. In human Jurkat cells that were stressed with hydrogen peroxide, over 2000 oxidation-sensitive methionines in more than 1600 different proteins were mapped and their extent of oxidation was quantified. Meta-analysis of the sequences surrounding the oxidized methionine residues revealed a high preference for neighboring polar residues. Using synthetic methionine sulfoxide containing peptides designed according to the observed sequence preferences in the oxidized Jurkat proteome, we discovered that the substrate specificity of the cellular methionine sulfoxide reductases is a major determinant for the steady-state of methionine oxidation. This was supported by a structural modeling of the MsrA catalytic center. Finally, we applied our method onto a serum proteome from a mouse sepsis model and identified 35 in vivo methionine oxidation events in 27 different proteins.
Oriented Modulation for Watermarking in Direct Binary Search Halftone Images (2012)

In this paper, a halftoning-based watermarking method is presented. This method enables high pixel-depth watermark embedding, while maintaining high image quality. This technique is capable of embedding watermarks with pixel depths up to 3 bits without causing prominent degradation to the image quality. To achieve high image quality, the parallel oriented high-efficient direct binary search (DBS) halftoning is selected to be integrated with the proposed orientation modulation (OM) method. The OM method utilizes different halftone texture orientations to carry different watermark data. In the decoder, the least-mean-square-trained filters are applied for feature extraction from watermarked images in the frequency domain, and the naïve Bayes classifier is used to analyze the extracted features and ultimately to decode the watermark data. Experimental results show that the DBS-based OM encoding method maintains a high degree of image quality and realizes the processing efficiency and robustness to be adapted in printing applications.
Acute His‐Bundle Injury Current during Permanent His‐Bundle Pacing Predicts Excellent Pacing Outcomes (2015)

IC can be recorded at the HB during permanent HBP in 37% of patients. HBIC is associated with significantly lower pacing thresholds compared to patients in whom HBIC was not recorded. HBIC may be a marker for superior short-term HBP thresholds.
Making Genes Green: Creating Green Fluorescent Protein (GFP) Fusions with Blunt-End PCR Products (1998)

The jellyfish green fluorescent protein (GFP) has proven to be a useful tool in protein localization and trafficking studies. Fused to GFP, a protein of interest can be visualized and tracked in vivo through fluorescence microscopy. However, the process of making these fusion proteins is often tedious and painstaking. Here, we describe a simple and quick method for creating GFP fusion proteins using blunt-end PCR product ligation.
A Survey of Authentication Mechanisms (2010)

Authentication is a common security issue for the design of Internet
protocols. A wide variety of authentication technologies are
available. A common problem is knowing which technology to choose or
which of a variety of essentially similar implementations of a given
technique to choose. This memo provides a survey of available
authentication mechanisms and guidance on selecting one for a given
protocol.
Learning Behavior Trees From Demonstration (2019)

Robotic Learning from Demonstration (LfD) allows anyone, not just experts, to program a robot for an arbitrary task. Many LfD methods focus on low level primitive actions such as manipulator trajectories. Complex multistep task with many primitive actions must be learned from demonstration if LfD is to encompass the full range of task a user may desire. Existing methods represent the high level task in various forms including, finite state machines, decision trees, formal logic, among others. Behavior trees are proposed as an alternative representation of high level task. Behavior trees are an execution model for the control of a robot designed for real time execution, modularity, and, consequently, transparency. Real time execution allows the robot to reactively perform the task. Modularity allows the reuse of learned primitive actions and high level task in new situations, speeding up the process of learning in new scenarios. Transparency allows users to understand and interactively modify the learned model. Behavior trees are used to represent high level tasks by building on the relationship it has with decision trees. We demonstrate a human teaching our Fetch robot a household cleaning task.
Linewidth narrowing and Purcell enhancement in photonic crystal cavities on an Er-doped silicon nitride platform (2010)

Light emission at 1.54 microm from an Er-doped amorphous silicon nitride layer coupled to photonic crystal resonators at cryogenic and room temperatures and under varying optical pump powers has been studied. The results demonstrate that small mode volume, high quality factor resonators enhance Er absorption and emission rates at the cavity resonance. Time resolved measurements give 11- to 17-fold Purcell enhancement of spontaneous emission at cryogenic temperatures, and 2.4-fold enhancement at room temperature. Resonances exhibit linewidth narrowing with pump power, signifying absorption bleaching and partial inversion of the Er ions cryogenic temperatures. We estimate that 31% of Er ions are excited at the highest pump power.