gebhart/patrepeval huggingface dataset:
Reticulated vitreous carbon: a useful material for cell adhesion and tissue invasion (2010)

Diverse carbon materials have been used for tissue engineering and clinical implant applications with varying success. In this study, commercially available reticulated vitreous carbon (RVC) foams were tested in vitro and in vivo for compatibility with primary cell adhesion and tissue repair. Pores sizes were determined as 279 ± 98 μm. No hydroxyapatite deposition was detected after immersion of the foams in simulated body fluid. Nonetheless, RVC provided an excellent support for adhesion of mesenchymal stem cells (MSCs) as well as primary chondrocytes without any surface pre-treatment. Live cell quantification revealed neutral behaviour of the material with plastic adhered chondrocytes but moderate cytotoxicity with MSCs. Yet, rabbit implanted foams exhibited good integration in subcutaneous pockets and most importantly, total defect repair in bone. Probably due to the stiffness of the material, incompatibility with cartilage regeneration was found. Interestingly and in contrast to several other carbon materials, we observed a total lack of foreign body reactions. Our results and its outstanding porous interconnectivity and availability within a wide range of pore sizes convert RVC into an attractive candidate for tissue engineering applications in a variety of bone models and for ex vivo cell expansion for regenerative medical applications.
Improvement of subharmonic injection schemes for huge hydro-generator stator ground fault protection (2003)

The stator winding of huge hydrogenerator unit has large leakage capacitance to earth. Traditional subharmonic injection schemes for generator stator grounding fault protection have poor performance in detecting high impedance grounding faults (HIGF). In order to improve them, a reactor added in parallel with the resistance in the secondary of a neutral grounding distribution transformer is applied to compensate the leakage capacitance in the paper. By measuring the voltage and current of the resonant signal injected from the additional reactor, grounding fault resistance can be calculated directly and HIGF protection for 100% generator stator windings is proposed. Simulation results show that the improved subharmonic injection scheme can detect HIGF with fault resistance higher than 8 k/spl Omega/.
A method for constructing decodable de Bruijn sequences (1996)

We present two related methods of construction for de Bruijn (1946) sequences, both based on interleaving "smaller" de Bruijn sequences. Sequences obtained using these construction methods have the advantage that they can be "decoded" very efficiently, i.e., the position within the sequence of any particular "window" can be found very simply. Sequences with simple decoding algorithms are of considerable practical importance in position location applications.
Multispectral Classification With Bias-Tunable Quantum Dots-in-a-Well Focal Plane Arrays (2010)

Mid-wave and long-wave infrared (IR) quantum-dots-in-a-well (DWELL) focal plane arrays (FPAs) are promising technology for multispectral (MS) imaging and sensing. The DWELL structure design provides the detector with a unique property that allows the spectral response of the detector to be continuously, albeit coarsely, tuned with the applied bias. In this paper, a MS classification capability of the DWELL FPA is demonstrated. The approach is based upon: 1) imaging an object repeatedly using a sequence of bias voltages in the tuning range of the FPA and then 2) applying a classification algorithm to the totality of readouts, over multiple biases, at each pixel to identify the “class” of the material. The approach is validated for two classification problems: separation among different combinations of three IR filters and discrimination between rocks. This work is the first demonstration of the MS classification capability of the DWELL FPA.
Whole Brain Imaging with Serial Two-Photon Tomography (2016)

Imaging entire mouse brains at submicron resolution has historically been a challenging undertaking and largely confined to the province of dedicated atlasing initiatives. This has limited systematic investigations into important areas of neuroscience, such as neural circuits, brain mapping and neurodegeneration. In this article, we describe in detail Serial Two-Photon (STP) tomography, a robust, reliable method for imaging entire brains with histological detail. We provide examples of how the basic methodology can be extended to other imaging modalities, such as Optical Coherence Tomography (OCT), in order to provide unique contrast mechanisms. Furthermore, we provide a survey of the research that STP tomography has enabled in the field of neuroscience, provide examples of how this technology enables quantitative whole brain studies, and discuss the current limitations of STP tomography-based approaches.
Kinetics of uptake and incorporation of meso-diaminopimelic acid in different Escherichia coli strains (1985)

The rate at which the peptidoglycan precursor meso-diaminopimelic acid (DAP) is incorporated into the cell wall of Escherichia coli cells was determined by pulse-label experiments. For different E. coli strains, the incorporation rate was compared with the rate of uptake of DAP into the cell. With E. coli W7, a dap lys mutant generally used in this kind of studies, steady-state incorporation was reached only after about 0.75 of the doubling time. This lag period can be ascribed to the presence of a large internal DAP pool in the cells. An E. coli K-12 lysA strain was constructed which could be grown without DAP in its medium. Consequently, due to the higher specific activity of the added [3H]DAP, faster incorporation and higher levels of radioactivity in the peptidoglycan layer were observed in the K-12 lysA strain than in the W7 strain. In addition, uptake and incorporation were faster in steady state (within about 0.2 of the doubling time), indicating a smaller DAP pool. The lag period could be further diminished and the incorporation rate could be increased by feedback inhibition of the biosynthetic pathway to DAP with threonine and methionine. These results make MC4100 lysA a suitable strain for studies on peptidoglycan synthesis. To explain our observations, we suggest the existence of an expandable pool of DAP in E. coli which varies with the DAP concentration in the growth medium. With 2 microgram of DAP per ml, the size of the pool is severalfold the amount of DAP contained in the cell wall. This pool can be partly washed out of the cells. Grown without DAP, MC4100 lysA still has a small pool caused by endogenous synthesis, which accounts for the fact that steady-state [3H]DAP incorporation in the lysA strain still shows a lag period.
Sintaxis y paradigmas (con especial referencia a la lengua española) (1988)

Our study suggests that NSCLC patients who are preoperatively negative for all serum TMs, such as CEA, CYFRA21-1, CA19-9, and SCC Ag, represent a subgroup with a particularly good prognosis.
Frugal Streaming for Estimating Quantiles:One (or two) memory suffices (2014)

Modern applications require processing streams of data for estimating statistical quantities such as quantiles with small amount of memory. In many such applications, in fact, one needs to compute such statistical quantities for each of a large number of groups, which additionally restricts the amount of memory available for the stream for any particular group. We address this challenge and introduce frugal streaming, that is algorithms that work with tiny -- typically, sub-streaming -- amount of memory per group. We design a frugal algorithm that uses only one unit of memory per group to compute a quantile for each group. For stochastic streams where data items are drawn from a distribution independently, we analyze and show that the algorithm finds an approximation to the quantile rapidly and remains stably close to it. We also propose an extension of this algorithm that uses two units of memory per group. We show with extensive experiments with real world data from HTTP trace and Twitter that our frugal algorithms are comparable to existing streaming algorithms for estimating any quantile, but these existing algorithms use far more space per group and are unrealistic in frugal applications; further, the two memory frugal algorithm converges significantly faster than the one memory algorithm.
Mononuclear and binuclear chromium(III) picolinate complexes (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMononuclear and binuclear chromium(III) picolinate complexesDiane M. Stearns and William H. ArmstrongCite this: Inorg. Chem. 1992, 31, 25, 5178–5184Publication Date (Print):December 1, 1992Publication History Published online1 May 2002Published inissue 1 December 1992https://pubs.acs.org/doi/10.1021/ic00051a007https://doi.org/10.1021/ic00051a007research-articleACS PublicationsRequest reuse permissionsArticle Views639Altmetric-Citations97LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A user study of the expandable grid applied to P3P privacy policy visualization (2009)

No abstract available.
Entity disambiguation in tweets leveraging user social profiles (2013)

Pervasive web and social networks are becoming part of everyone's life. Users through their activities on these networks are leaving traces of their expertise, interests and personalities. With the advances in Web mining and user modeling techniques it is possible to leverage the user social network activity history to extract the semantics of user-generated content. In this work we explore various techniques for constructing user profiles based on the content they publish on social networks. We further show that one of the advantages of maintaining social network user profiles is to provide the context for better understanding of microposts. We propose and experimentally evaluate different approaches for entity disambiguation in social networks based on syntactic and semantic features on top of two different social networks: a general-interest network (i.e., Twitter) and a domain-specific network (i.e., StackOverflow). We demonstrate how disambiguation accuracy increases when considering enriched user profiles integrating content from both social networks.
Convolutional Neural Networks for No-Reference Image Quality Assessment (2014)

In this work we describe a Convolutional Neural Network (CNN) to accurately predict image quality without a reference image. Taking image patches as input, the CNN works in the spatial domain without using hand-crafted features that are employed by most previous methods. The network consists of one convolutional layer with max and min pooling, two fully connected layers and an output node. Within the network structure, feature learning and regression are integrated into one optimization process, which leads to a more effective model for estimating image quality. This approach achieves state of the art performance on the LIVE dataset and shows excellent generalization ability in cross dataset experiments. Further experiments on images with local distortions demonstrate the local quality estimation ability of our CNN, which is rarely reported in previous literature.
Gradient Mixed Brushes:  “Grafting To” Approach (2004)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTGradient Mixed Brushes: "Grafting To" ApproachLeonid Ionov, Alexander Sidorenko, Manfred Stamm, Sergiy Minko, Bogdan Zdyrko, Viktor Klep, and Igor LuzinovView Author Information Institute for Polymer Research Dresden, Dresden, Germany Chemistry Department, Clarkson University, Potsdam, New York 13699 School of Materials Science and Engineering, Clemson University, Clemson, South Carolina 29634 Cite this: Macromolecules 2004, 37, 19, 7421–7423Publication Date (Web):August 17, 2004Publication History Received30 April 2004Revised1 July 2004Published online17 August 2004Published inissue 1 September 2004https://pubs.acs.org/doi/10.1021/ma049147rhttps://doi.org/10.1021/ma049147rbrief-reportACS PublicationsCopyright © 2004 American Chemical SocietyRequest reuse permissionsArticle Views1324Altmetric-Citations101LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Aromatic compounds,Layers,Polymers,Solvents,Thickness Get e-Alerts
THE INFORMATION OF THE MILKY WAY FROM TWO MICRON ALL SKY SURVEY WHOLE SKY STAR COUNT: THE LUMINOSITY FUNCTION (2010)

The logarithmic differential star count of the Two Micron All Sky Survey in Ks band can be well approximated by a single power-law luminosity function. With a fiducial Galactic structure, we measure the luminosity function for the entire Milky Way. The distribution of the power-law index is roughly isotropic and shows no obvious trend with the Galactic latitude. The value for the power-law index, the bright and the faint ends of the luminosity function are 1.85 ± 0.035, Ks = −7.86 ± 0.60 mag, and Ks = 6.88 ± 0.66 mag, respectively. Our result strongly supports the notion of a universal luminosity function in our Galaxy. We also find that the luminosity function of LMC/SMC is similar to that of the Milky Way.
Studies on the Development of Intragastric Floating and Sustained Release Preparation. I. Application of Calcium Silicate as a Floating Carrier. (1996)

We prepared an intragastric floating preparation using porous calcium silicate (Florite[○!R] RE, FLR) as a floating carrier, which has floating ability due to the air included in the pores when they are covered with a polymer, it also has a sustained drug release property. Floating granules were prepared by dropping a 5 or 10% (w/v) ethanol solution of hydroxypropylcellulose (HPC) and ethylcellulose (EC) in 4 different concentration ratios while the FLR was being agitated in a beaker. After the mixture was dried in vacuo and sieved, we regarded the granules obtained as primary coated granules (PCG). After drying, the ethanol solution of the polymer was dropped and dried in vacuo again, and sieving was carried out to obtain secondary coated granules (SCG). The floating property and surface and inner structures of PCG and SCG were studies. Further, we prepared PCG and SCG including diclofenac sodium (DS) (DS-PCG, DS-SCG) as a model drug, and the drug release profile from these granules was observed.The floating property of SCG was better than that of PCG. A longer floating time was observed with a higher polymer concentration and a lower HPC composition ratio. It was observed by a scanning electron microscope (SEM) and the pore size distribution that more pores of FLR in SCG were covered with polymer than those in PCG. DS-SCG showed a smaller release rate than DS-PCG. These results suggest that FLR is a useful floating carrier for the development of floating and sustained release preparations.
EFFECT OF EXPLANTS TYPE AND PLANT GROWTH REGULATORS ON IN VITRO CALLUS INDUCTION AND SHOOT REGENERATION OF CANNABIS SATIVA L. (2016)

شاهدانه ایرانی ( Cannabis sativa  L.) گیاهی دارویی متعلق به خانواده Cannabinaceae است که ترکیب‌های متنوعی از متابولیت‌های ثانویه را تولید می‌کند. این تحقیق به‌منظور بهینه‌سازی باززایی مستقیم و غیرمستقیم این گیاه در شرایط in vitro انجام شد. ریزنمونه‌های برگ و هیپوکوتیل از گیاهچه‌های استریل جداسازی شده و محیط کشت‌های حاوی BA (1/0، 2/0، 5/0، 1، 2، 3 میلی‌گرم در لیتر) به تنهایی یا در ترکیب با 5/0 میلی‌گرم در لیتر IBA و TDZ (1/0، 2/0، 5/0، 1، 2، 3 میلی‌گرم در لیتر) به تنهایی یا در ترکیب با 5/0 میلی‌گرم در لیتر IBA کشت شدند. عکس‌العمل ریزنمونه‌ها در همه محیط‌های کشت مورد استفاده، تولید کالوس بود. هیچگونه باززایی مستقیم در ریزنمونه‌ها مشاهده نشد و در ریزنمونه هیپوکوتیل باززایی غیرمستقیم در سطوح مختلف هورمونی BA اتفاق افتاد. بیشترین حجم کالوس تولید شده، در غلظت 2 میلی‌گرم در لیتر TDZ به همراه 5/0 میلی‌گرم در لیتر IBA در ریزنمونه برگ بدست آمد. بیشترین وزن تر و خشک کالوس تولید شده مربوط به ریزنمونه برگ در تیمار هورمونی 1 میلی‌گرم در لیتر TDZ به همراه 5/0 میلی‌گرم در لیتر IBA بود. تیمار هورمونی 5/0 میلی‌گرم در لیتر TDZ به همراه 5/0 میلی‌گرم IBA در هیچ ریزنمونه‌ای کالوس تولید نکرد. البته ترکیب هورمون IBA در غلظت‌های مختلف هورمون BA، تأثیر شگرفی در بهبود حجم و وزن تر و خشک کالوس ریزنمونه‌ها داشت. با این حال افزودن هورمون IBA در غلظت‌های مختلف هورمون TDZ چندان تأثیری در بهبود حجم و وزن تر و خشک کالوس هر دو ریزنمونه نداشت.
Statistical Total Correlation Spectroscopy:  An Exploratory Approach for Latent Biomarker Identification from Metabolic <sup>1</sup>H NMR Data Sets (2005)

We describe here the implementation of the statistical total correlation spectroscopy (STOCSY) analysis method for aiding the identification of potential biomarker molecules in metabonomic studies based on NMR spectroscopic data. STOCSY takes advantage of the multicollinearity of the intensity variables in a set of spectra (in this case 1H NMR spectra) to generate a pseudo-two-dimensional NMR spectrum that displays the correlation among the intensities of the various peaks across the whole sample. This method is not limited to the usual connectivities that are deducible from more standard two-dimensional NMR spectroscopic methods, such as TOCSY. Moreover, two or more molecules involved in the same pathway can also present high intermolecular correlations because of biological covariance or can even be anticorrelated. This combination of STOCSY with supervised pattern recognition and particularly orthogonal projection on latent structure-discriminant analysis (O-PLS-DA) offers a new powerful framework for analysis of metabonomic data. In a first step O-PLS-DA extracts the part of NMR spectra related to discrimination. This information is then cross-combined with the STOCSY results to help identify the molecules responsible for the metabolic variation. To illustrate the applicability of the method, it has been applied to 1H NMR spectra of urine from a metabonomic study of a model of insulin resistance based on the administration of a carbohydrate diet to three different mice strains (C57BL/6Oxjr, BALB/cOxjr, and 129S6/SvEvOxjr) in which a series of metabolites of biological importance can be conclusively assigned and identified by use of the STOCSY approach.
Analytical and experimental investigation of bird impact on fan and compressor blading (1984)

Etude analytique et experimentale du choc d'un oiseau sur l'aubage d'une soufflante et d'un compresseur
The potential impact of soil carbon content on ground water nitrate contamination (1996)

A potential buildup of nitrate in the ground water resources of the eastern Sandhills of Nebraska has been projected to occur due to the intensive use of nitrogen fertilizer on irrigated cropland. A root-zone nitrate leaching study in this area revealed that soils with a high carbon concentration had minimal leaching compared to soils with lower concentrations. Soils high in carbon have an active population of denitrifying bacteria possibly causing denitrification and in turn reduction of nitrate leaching. Denitrifying bacteria are principally heterotrophic using soil organic carbon for both an energy and carbon source. The objective of this research was to interpret how root-zone denitrification affected nitrate leaching and ground water contamination by nitrate. A modified version of a solute transport model developed for the Eastern Sandhills was used to assess the risk of nitrate contamination for combinations of fertilizer and irrigation rates and for various soil carbon levels. The first attempt was to make risk assessment with eight farm management practices for cells with increasingly greater carbon levels until only those cells with the greatest carbon level were kept in production. Results of this assessment showed that even with excessive fertilizer and irrigation rates, risk of nitrate leaching was reduced as the minimum carbon level was increased. However, since less cropland was leaching nitrate with each successive risk calculation, the impact that root-zone denitrification had in nitrate leaching reduction could not be definitively determined. This prompted a model modification of the risk calculation procedure which kept all cropland in production and computed nitrate leachate risk for increasingly higher artificial carbon levels during successive risk calculations. Changing carbon levels was still more detrimental on nitrate leaching rates than changing farm management practices.
Prestimulation of CD2 confers resistance to HIV-1 latent infection in blood resting CD4 T cells (2021)

HIV-1 infects blood CD4 T cells through the use of CD4 and CXCR4 or CCR5 receptors, which can be targeted through blocking viral binding to CD4/CXCR4/CCR5 or virus-cell fusion. Here we describe a novel mechanism by which HIV-1 nuclear entry can also be blocked through targeting a non-entry receptor, CD2. Cluster of differentiation 2 (CD2) is an adhesion molecule highly expressed on human blood CD4, particularly, memory CD4 T cells. We found that CD2 ligation with its cell-free ligand LFA-3 or anti-CD2 antibodies rendered blood resting CD4 T cells highly resistant to HIV-1 infection. We further demonstrate that mechanistically, CD2 binding initiates competitive signaling leading to cofilin activation and localized actin polymerization around CD2, which spatially inhibits HIV-1-initiated local actin polymerization needed for viral nuclear migration. Our study identifies CD2 as a novel target to block HIV-1 infection of blood resting T cells.
The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal. (2012)

CA 19-9 is the most extensively studied and validated serum biomarker for the diagnosis of pancreatic cancer in symptomatic patients. CA 19-9 serum levels can provide important information with regards to prognosis, overall survival, and response to chemotherapy as well as predict post-operative recurrence. However, non-specific expression in several benign and malignant diseases, false negative results in Lewis negative genotype and an increased false positive results in the presence of obstructive jaundice severely limit the universal applicability of serum CA 19-9 levels in pancreatic cancer management.