gebhart/patrepeval huggingface dataset:
Beyond usability (2009)

The role of emotion as an integral component of user experience has mostly been overlooked in the HCI literature. Instead, usability has been relied upon as the key indicator of user experience. We developed a methodology that combined verbal and nonverbal emotion scales. A usability study was then conducted, in which we collected both traditional usability metrics and emotional response data. Results indicated insignificant differences in usability metrics but numerous significant differences between emotional responses of users. Exploration of these emotional responses successfully provided additional insight into the user experience.
Generative Models for Clustering: The Next Generation. (2008)

Clustering social information is challenging when both at-tributes and relations are present. Many approaches com-monly used today ignore one aspect of the data or the other. Relation-only algorithms are typically limited because the sparseness of relations in social information makes finding strong patterns difficult. Feature-only algorithms have the limitation that the most interesting (and useful) aspect of so-cial information is the set of relations between objects. Re-cently, there has been a surge in interest in simultaneously considering both features and relations in the operation of a clustering algorithm. Several of these approaches are based on a generative model, which corresponds to an assumption that the data exists as part of some unobserved probability distribution. Each of the approaches discussed in this paper have good initial results. After discussing each in turn, we discuss in broad terms what has been accomplished thus far with generative models, what open problems remain, and how the development of generative models for relational data can contribute to the field of social information processing.
Pharmacology of Connexin Channels (2008)

Connexin channels play a wide variety of roles in different cell types and tissues. Genetic and molecular approaches have proven useful for understanding the roles of these proteins in tissue function. Identification and characterization of specific and high-affinity inhibitors of these channels would greatly assist investigation of their physiological function; however, progress in this area has been slow. Nevertheless, recent studies have identified a number of small molecules and peptides that inhibit connexin channels. Although the specificity of these new drugs for connexin channels remains problematic, several of these reagents inhibit channels in an isoform-specific manner and do so with reasonable potency. These reagents are likely to be useful for acute studies that investigate the physiological roles of different connexin channels. In addition, some agents appear to bind within the permeability pathway and may be useful in structure-function studies of the pore.
Adaptive parameter estimation using parallel Kalman filtering for spread spectrum code and doppler tracking (1994)

We present a new digital direct-sequence (DS) receiver with joint estimation of code delay, multipath gains and Doppler shift. A parameter estimator consisting of a parallel bank of extended Kalman filters (EKF’s) extracts estimates of the timing, T and the multipath coefficients, fl distorting the received signal. A "detected" estimate of the Doppler shift, Vr distorting the received signal is also provided by the estimator. We compute the bit error rate that results when a RAKE matched filter uses the estimated parameters to detect the DPSK encoded binary data in the received signal. The bit-error rate (BER) is evaluated, and successful performance of the proposed receiver in the presence of Doppler shift distortion is observed in many cases. We demonstrate that the receiver can operate when the multipath coefficients vary in time (Doppler spread).
Some effects of a tick infestation <i>(Haemaphysalis longicornis)</i> on sheep (1977)

Abstract Weight gain, wool production, packed cell volume, and haemoglobin levels (“tick effects„) were reduced in undipped 2‐tooth ewes exposed to a naturally acquired infestation of the tick, Haemaphysalis longicornis . Mean adult tick counts reached a maximum of 27.8 per undipped sheep, the “tick effects” being evident on the 16th and 35th days following this peak. Mean tick counts on a control group of dipped animals were less than two per sheep.
Carrier envelope offset detection via simultaneous supercontinuum and second-harmonic generation in a silicon nitride waveguide (2018)

We demonstrate a chip-scale f-2f interferometer for carrier-envelope-offset frequency (f<sub>CEO</sub>) detection. This is enabled by simultaneously producing octave-spanning coherent supercontinuum generation and second-harmonic generation in a single dispersion-engineered silicon nitride waveguide. We measure the f<sub>CEO</sub> beatnote of an 80 MHz modelocked pump source with a signal-to-noise ratio of 25 dB. Our simple approach for f-2f interferometry enables a straightforward route towards a chip-scale self-referenced frequency comb source that can operate at low pulse energies.
An in vitro model for the scintigraphic detection of thrombi using a 99Tcm-labelled antifibrin monoclonal antibody (1989)

Because of their specific targeting properties, monoclonal antibodies have found widespread use in nuclear medicine. In this paper, a method is described for the evaluation of immunoscintigraphic parameters for the detection of thrombi, using a 99Tcm-labelled antifibrin monoclonal antibody (designated as Y22). An in vitro model was developed to evaluate the effects of various environmental conditions on uptake by plasma clots of 99Tcm-Tc-Y22 in circulating plasma on a gamma camera. The clots became visible as hotspots after approximately 1 h of circulation of 99Tcm-Y22 containing citrated plasma at 37 degrees C. Circulation of 99Tcm-fibrinogen, 99Tcm-HSA or 99Tcm-control MoAb did not show visible uptake by the clots under the same conditions. At 37 degrees C, 99Tcm-Y22 accumulated approximately four times faster than at 20 degrees C. Heparin did not affect binding of the antibody to clots. To assess the feasibility of thrombus detection in vivo, an extracorporeal rat thrombus model was used. A thrombus in a shunt between a carotid artery and a jugular vein became visible 1 h after injection of the labelled Y22 and, more clearly, after 3 h.
Shipping Out MEK Inhibitor Resistance with SHP2 Inhibitors (2018)

<b> <i>RAS</i> is one of the most frequently altered oncogenes, yet RAS-driven tumors are largely refractory to anticancer therapies. Fedele and colleagues demonstrate that SHP2 inhibitors prevent adaptive MEK inhibitor resistance; therefore, combining MEK and SHP2 inhibitors represents an exciting new therapeutic approach for the treatment of RAS-driven cancers. <i>Cancer Discov; 8(10); 1210-2. ©2018 AACR.</i> <i>See related article by Fedele et al., p. 1237</i>.</b>
Pressure-Induced Amorphization of Small Pore Zeolites—the Role of Cation-H2O Topology and Anti-glass Formation (2015)

Systematic studies of pressure-induced amorphization of natrolites (PIA) containing monovalent extra-framework cations (EFC) Li(+), Na(+), K(+), Rb(+), Cs(+) allow us to assess the role of two different EFC-H2O configurations within the pores of a zeolite: one arrangement has H2O molecules (NATI) and the other the EFC (NATII) in closer proximity to the aluminosilicate framework. We show that NATI materials have a lower onset pressure of PIA than the NATII materials containing Rb and Cs as EFC. The onset pressure of amorphization (PA) of NATII materials increases linearly with the size of the EFC, whereas their initial bulk moduli (P1 phase) decrease linearly. Only Cs- and Rb-NAT reveal a phase separation into a dense form (P2 phase) under pressure. High-Angle Annular Dark Field Scanning Transmission Electron Microscopy (HAADF-STEM) imaging shows that after recovery from pressures near 25 and 20 GPa long-range ordered Rb-Rb and Cs-Cs correlations continue to be present over length scales up to 100 nm while short-range ordering of the aluminosilicate framework is significantly reduced-this opens a new way to form anti-glass structures.
Decreasing arsenic accumulation in rice by overexpressing <i>Os<scp>NIP</scp>1;1</i> and <i>Os<scp>NIP</scp>3;3</i> through disrupting arsenite radial transport in roots (2018)

Rice is a major dietary source of the toxic metalloid arsenic. Reducing arsenic accumulation in rice grain is important for food safety. We generated transgenic rice overexpressing two aquaporin genes, OsNIP1;1 and OsNIP3;3, under the control of a maize ubiquitin promoter or the rice OsLsi1 promoter, and tested the effect on arsenite uptake and translocation. OsNIP1;1 and OsNIP3;3 were highly permeable to arsenite in Xenopus oocyte assays. Both transporters were localized at the plasma membrane. Knockout of either gene had little effect on arsenite uptake or translocation. Overexpression of OsNIP1;1 or OsNIP3;3 in rice did not affect arsenite uptake but decreased root-to-shoot translocation of arsenite and shoot arsenic concentration markedly. The overexpressed OsNIP1;1 and OsNIP3;3 proteins were localized in all root cells without polarity. Expression of OsNIP1;1 driven by the OsLsi1 promoter produced similar effects. When grown in two arsenic-contaminated paddy soils, overexpressing lines contained significantly lower arsenic concentration in rice grain than the wild-type without compromising plant growth or the accumulation of essential nutrients. Overexpression of OsNIP1;1 or OsNIP3;3 provides a route for arsenite to leak out of the stele, thus restricting arsenite loading into the xylem. This strategy is effective in reducing arsenic accumulation in rice grain.
Transcriptional Profiling of Rhesus Monkey Embryonic Stem Cells1 (2006)

Embryonic stem cells (ESCs) may be able to cure or alleviate the symptoms of various degenerative diseases. However, unresolved issues regarding survival, functionality, and tumor formation mean a prudent approach should be adopted towards advancing ESCs into human clinical trials. The rhesus monkey provides an ideal model organism for developing strategies to prevent immune rejection and test the feasibility, safety, and efficacy of ESC-based medical treatments. Transcriptional profiling of rhesus monkey ESCs provides a foundation for pre-clinical ESC research in this species. In the present study, we used microarray technology, immunocytochemistry, reverse transcription polymerase chain reaction (RT-PCR) and quantitative real-time PCR (qPCR) to characterize and transcriptionally profile rhesus monkey ESCs. We identified 367 stemness gene candidates that were highly (>85%) conserved across five different ESC lines. Rhesus monkey ESC lines maintained a pluripotent undifferentiated state over a wide range of POU5F1 (also known as OCT4) expression levels, and comparisons between rhesus monkey, mouse, and human stemness genes revealed five mammalian stemness genes: CCNB1, GDF3, LEFTB, POU5F1, and NANOG. These five mammalian genes are strongly expressed in rhesus monkey, mouse, and human ESCs, albeit only in the undifferentiated state, and represent the core key mammalian stemness factors.
Tropism of human herpesvirus 8 for peripheral blood lymphocytes in patients with Castleman's disease (1997)

Multicentric Castleman's disease (MCD), also called multicentric angiofollicular lymphoid hyperplasia, is a systemic lymphoproliferative disorder causing fever, lymphadenopathy and splenomegaly. Recently, Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) DNA sequences have been detected in cases of MCD. We examined HHV-8 DNA sequences in the peripheral blood mononuclear cells (PBMCs) of two HIV-negative patients with MCD and in PBMCs and the lymph node of a HIV-negative patient with localized Castleman's disease (LCD) by the polymerase chain reaction. The novel sequences were detected in all DNA samples. Furthermore, the sequences were detected in only the CD19+ B-lymphocyte fraction of the patient with LCD as previously reported. However, the sequences were detected in CD19+ B-lymphocyte and CD2+ T-lymphocyte fractions of two patients with MCD. These results suggest that HHV-8 has tropisms for both B lymphocytes and T lymphocytes in Castleman's disease.
Power System Planning (2016)

This chapter introduces the power system planning which is often divided into generation planning, transmission planning, and distribution planning. The aim of generation planning is to seek the most economical generation expansion scheme that achieves a certain reliability level according to the forecast of demand growth in a certain period of time. The mathematical model of generation planning generally consists of two parts: the power plant investment decision, and power system operation planning. The object of transmission system planning is to determine when, where, and what type of transmission line should be constructed, under the condition that the generation planning and load forecasting in the planning stage are known. Transmission planning aims at strengthening an existing transmission network to serve power producers and customers in an optimal way. Demand-side response (DSR) is important for integrated planning of the power distribution network, especially the current large-scale access of distributed generation (DG).
Two Acylated Diarylheptanoid Glycosides from Red Alder Bark (1998)

Two novel acylated diarylheptanoid glycosides, oregonosides A and B (3, 4, respectively), were isolated from red alder bark and their structures established by spectrometric techniques. The compounds were identified as (5S)-1,7-bis(3, 4-dihydroxyphenyl)-5-O-(6-O-benzoyl-beta-D-glucopyranosyl)-heptan-3-o ne and (5S)-1,7-bis(3, 4-dihydroxyphenyl)-5-O-(6-O-vanilloyl-beta-D-glucopyranosyl)-heptan-3 -one.
Compliant Prestress Fixation in Tumor Prostheses: Interface Retrieval Data (2000)

This article reports the first available human retrieval data following the use of a new fixation system for tumor prostheses. The compliant prestress (CPS) fixation system obviates the need for long intramedullary stems. The CPS was designed to provide a stable, high-pressure, motion-free bone-implant interface that would prevent aseptic loosening and allow osseointegration at the bone-implant interface. At 10 months, the fourth patient in the human trial required amputation. Backscatter electron microscopy revealed a buttress of new bone had formed along 70% of the bone-metal interface, with excellent bony ingrowth (average: 42%) into the transverse, porous-coated titanium interface.
Analysis of Stacked Rectangular Microstrip Antenna (2007)

A stacked microstrip antenna with C-type feed is designed in order to enhance the bandwidth. The effect of the various parameters, such as the rotation feed angle (thetas), the variations of relative permittivity of parasitic patch (epsiv <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r2</sub> ), the distance of the feed point from the center (r), and the separation between two stacked patches (h <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ), have been discussed. Some designs give a good return loss under -40 dB and wide VSWR bandwidth, such as case#2 with epsiv <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r2</sub> =4.26, case#4 with r=6.2 mm, case#5 with h <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> =6.8 mm, case#1,and case#2 with h <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> =8.2 mm. The simulated data are obtained using the IE3D simulator with method of moments (MoM) commercial code. An infinite ground plane has been considered for simulations; however, and due to a software constraint, substrate dimensions are infinite.
The evaluation of different base materials for high density flip chip on flex applications (2001)

This paper presents the results from the evaluation of different types of flexible substrates for high‐density flip chip application. In this work two different types of base materials were used, epoxiglass (EG) and polyimide (PI). According to previous tests the type of conductive particles in the adhesive seems to be one of the key factors in high‐density interconnections. The adhesive selected for these tests was a composite of epoxy matrix and high content of isolated soft metal‐coated polymer particles. Two different test structures with contact areas of 50 × 50μm and 50 × 90μm were compared. The total amount of contacts in one IC was approximately 200 and the effective pitch size was 80μm. The contact resistances were measured by four‐point method and the continuity by daisy chain structure. The reliability of the flip chip interconnections was tested in thermal cycling and humidity tests.
Interest in Production (2006)

The chapter locates the organization of the technology-bearing labor process as an important object of STS/ e-science research. Prospective e-science texts, so central to the pursuit of innovative technologies, construct images of specific technical product outcomes that could justify future investment; such products in turn imply specific labor contributions. To study the production of IT for epistemic practice is to go beyond an inquiry of IT use and design practices, and to consider decisions that get made about how the skill, commitment, performance and product demand of scientists could be coordinated and stabilized. In bringing these considerations to the fore, the chapter presents findings from a study about a particular e-science infrastructure production project—the U.S. National Computational Science Alliance—at the turn of the 21st century. The chapter illustrates the organizational dynamics in this case that were bound up with the garnering of interest and commitment of scientists who were funded to build interdisciplinary computational media.
METHODS FOR PROTECTING SOYBEAN AND CANOLA PROTEINS FROM DEGRADATION IN THE RUMEN (1984)

Soybean and canola proteins were treated with heat, formaldehyde (HCHO), sodium hydroxide (NaOH), whole fresh blood (BL) or fish hydrolysate (FH). Effect of these treatments on in situ protein degradability was measured by the nylon bag technique using fisulated steers. All treatments with the exception of heat were effective in protecting protein of soybeans and soybean meal (SBM). Canola seed protein was protected with heat at 110 °C for 2 h and with chemical treatments; all treatments were effective in protecting canola meal (CM) protein. Essential amino acid profiles of these residues from HCHO- or NaOH-treated SBM were not different from untreated SBM residue but increases in some essential amino acids were found in BL-treated SBM residue. Rat bioassays of residues from nylon bag studies revealed that protein quality of SBM, as indicated by net protein ratio, was significantly reduced (P < 0.05) by addition of HCHO, NaOH, BL or FH. Protein digestibility of SBM and CM was decreased by HCHO treatment but not by other treatments. NaOH treatment of CM had no effect on protein quality but HCHO, BL or FH treatments significantly improved (P < 0.05) protein quality of CM residue compared with untreated CM residue. These studies demonstrate that soybean and canola proteins can be effectively protected from degradation in the rumen by NaOH, BL or FH treatment without adverse effect on protein digestibility. Key words: Formaldehyde, sodium hydroxide, blood, fish hydrolysate, soybean, canola
Fe-substituted SrTiO3−δ–Ce0.9Gd0.1O2 composite anodes for solid oxide fuel cells (2013)

A new composite solid oxide fuel cell anode material, SrTi1−xFexO3−δ mixed with Gd-doped ceria, was tested in La0.9Sr0.1Ga0.8Mg0.2O3−δ electrolyte-supported cells with La0.4Ce0.6O2 barrier layers and La0.6Sr0.4Fe0.8Co0.2O3 cathodes. The x = 0.7 composition had an anode polarization resistance of 0.17 Ω cm2, at 800 °C in humidified H2, much lower than the value 0.39 Ω cm2 measured for x = 0.4 and 3.14 Ω cm2 for x = 0. The reduced polarization resistance correlated with increased oxygen non-stoichiometry δ, which suggests that it may be related to increased ionic conductivity. Electrochemical impedance spectroscopy (EIS) measurements at 800 °C on the x = 0.7 anode cell showed a main response centered at ∼1 Hz that increased with decreasing hydrogen partial pressure. The maximum power density observed was for the x = 0.7 cell – 337 mW cm−2 at 800 °C in air and humidified hydrogen – and was limited mainly by the thick electrolyte.
Gating characteristics of photomultiplier tubes for Lidar applications (1986)

A detector test facility was developed and applied in the evaluation and characterization of lidar detectors in support of the multipurpose airborne differential absorption lidar (DIAL) system based at the Langley Research Center (LaRC). A performance data base of various detector configurations available to the DIAL system was obtained for optimum lidar detector selection. Photomultiplier tubes (PMT's) with multialkaline and bialkaline photocathodes were evaluated in voltage-divider networks (bases) by using either the focusing electrode or dynodes as a gating mechanism. Characteristics used for detector evaluation included gain stability, signal rise time, and the ability to block unwanted high light levels.
Preparation of n-octadecaborane(22), n-B18H22, by oxidative fusion of dodecahydrononaborate(1-) clusters (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of n-octadecaborane(22), n-B18H22, by oxidative fusion of dodecahydrononaborate(1-) clustersDonald F. Gaines, Caterina K. Nelson, and Gail A. SteehlerCite this: J. Am. Chem. Soc. 1984, 106, 23, 7266–7267Publication Date (Print):November 1, 1984Publication History Published online1 May 2002Published inissue 1 November 1984https://pubs.acs.org/doi/10.1021/ja00335a079https://doi.org/10.1021/ja00335a079research-articleACS PublicationsRequest reuse permissionsArticle Views96Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts