gebhart/patrepeval huggingface dataset:
A 5 to 10 GHz low spurious triple tuned type PLL synthesizer driven by frequency converted DDS unit (2002)

This paper presents a 5 to 10 GHz low spurious triple tuned type PLL synthesizer with narrow channel steps for wide-band reception in RF measurement systems. The synthesizer is driven by a DDS to achieve such characteristics with a single PLL configuration. It corrects DDS's output frequency and division ratios of two variable frequency dividers in the PLL. With the proposed topology, high level spurious components by the DDS do not fall in from the PLL's loop bandwidth. An added frequency converter placed between the DDS and PLL also suppresses spurious level by reducing a transfer gain from the DDS to the PLL output. Furthermore, a voltage controlled oscillator (VCO) with inverted tuning circuits is presented for low phase noise characteristics. A developed PLL synthesizer with channel step 625 kHz achieved low spurious level below -46 dBc, phase noise of -105 dBc/Hz@1 MHz offset and switching speed of 90 /spl mu/s.
Cutting fluid study for single crystal silicon (1998)

An empirical study was conducted to evaluate cutting fluids for Single Point Diamond Turning (SPDT) of single crystal silicon. The pH of distilled waster was adjusted with various additives the examine the effect of pH on cutting operations. Fluids which seemed to promote ductile cutting appeared to increase tool wear as well, an undesirable tradeoff. High Ph sodium hydroxide solutions showed promise for further research, as they yielded the best combination of reduced tool wear and good surface finish in the ductile regime. Negative rake tools were verified to improve the surface finish, but the negative rake tools used in the experiments also showed much higher wear than conventional 0{degree} rake tools. Effects of crystallographic orientation on SPDT, such as star patterns of fracture damage forming near the center of the samples, were observed to decrease with lower feedrates. Silicon chips were observed and photographed, indicative of a ductile materials removal process.
Scalar-product based secure two-party computation (2008)

Secure multiparty computation is a very important research topic in cryptography. The sub-problem of secure multiparty computation that has received special attention by researchers because of its close relation to many cryptographic tasks is secure two-party computation. This area of research is concerned with the question: ldquoCan two party computation be achieved more efficiently and under weaker security assumptions than general multiparty computation?rdquo Yaopsilas protocol provided security against passive adversaries, while Lindell and Pinkas proposed secure two party protocols that are secure against active adversaries. In this paper, we would like to propose a set of information theoretically secure protocols based on scalar product protocol. The detailed complexity analysis is also provided.
M wave and H-reflex of soleus muscle before and after electrical muscle stimulation in healthy subjects. (2003)

It was suggested that the muscle fatigue was induced because the amplitude of maximal M wave significantly decreased after EMS in this study. And also it was suggested the excitability of spinal neural function corresponding with fatigued soleus muscle by EMS was not consist change in this study.
Multi-directional Reach Test: An Investigation of the Limits of Stability of People Aged between 20–79 Years (2014)

[Purpose] The multi-directional reach test (MDRT) is a simple, inexpensive, reliable and valid screening tool for assessing the limits of stability in the anterorposterior and mediolateral directions. The aim of this study was to quantify the limits of stability of people aged between 20 and 79 years using the MDRT. [Subjects] One hundred and eighty subjects were divided into the following 6 age groups: 20-29, 30-39, 40-49, 50-59, 60-69 and 70-79 years (n=30 per group). [Methods] The MDRT was used to measure the limits of stability in four directions: forward, backward, leftward and rightward. Subjects performed maximal outstretched arm reach in each direction with their feet flat on the floor. [Results] All age groups performed the greatest values of the limit of stability in the forward direction. The 60-79 year group demonstrated significantly lower limits of stability in the forward, leftward and rightward directions compared to the 20-39 year group. [Conclusion] The limits of stability declined with age mainly in the forward, leftward and rightward directions. The MDRT appears to be a useful assessment tool for postural control and balance of those aged 60 years and over.
Creating Relational Data from Unstructured and Ungrammatical Data Sources (2008)

In order for agents to act on behalf of users, they will have to retrieve and integrate vast amounts of textual data on the World Wide Web. However, much of the useful data on the Web is neither grammatical nor formally structured, making querying difficult. Examples of these types of data sources are online classifieds like Craigslist and auction item listings like eBay. We call this unstructured, ungrammatical data "posts." The unstructured nature of posts makes query and integration difficult because the attributes are embedded within the text. Also, these attributes do not conform to standardized values, which prevents queries based on a common attribute value. The schema is unknown and the values may vary dramatically making accurate search difficult. Creating relational data for easy querying requires that we define a schema for the embedded attributes and extract values from the posts while standardizing these values. Traditional information extraction (IE) is inadequate to perform this task because it relies on clues from the data, such as structure or natural language, neither of which are found in posts. Furthermore, traditional information extraction does not incorporate data cleaning, which is necessary to accurately query and integrate the source. The two-step approach described in this paper creates relational data sets from unstructured and ungrammatical text by addressing both issues. To do this, we require a set of known entities called a "reference set." The first step aligns each post to each member of each reference set. This allows our algorithm to define a schema over the post and include standard values for the attributes defined by this schema. The second step performs information extraction for the attributes, including attributes not easily represented by reference sets, such as a price. In this manner we create a relational structure over previously unstructured data, supporting deep and accurate queries over the data as well as standard values for integration. Our experimental results show that our technique matches the posts to the reference set accurately and efficiently and outperforms state-of-the-art extraction systems on the extraction task from posts.
Fast Switching Synthesizer (1985)

The most common approaches used for achieving large step fast synthesizer switching is to pretune the VCO by a coarse tuning voltage produced by a D/A circuit, or by using switching inductors in the VCO. Both solutions suffer from poor noise immunity and much circuit hardware. This paper presents a new technique for increasing the switching speed of high resolution PLL synthesizers. A novel solution is presented whereby the Reference Frequency is increased for a short period of time so as to increase the natural frequency of the loop ω <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</sub> and thereby accelerating the loop's acquisition time. After acquiring lock the Reference Frequency is changed back to its high resolution value. Experiments incorporating this technique were conducted with a 10-kHz step synthesizer that achieved a 1-msec lock-time for a 300 to 460 MHz change.
Optimizing meeting scheduling in collaborative mobile systems through distributed voting (2010)

Decision making through distributed voting can help automate routine-like collaborative tasks. In this paper we concentrate on how distributed voting strategies can be used for scheduling meetings in mobile and pervasive environments. Our work focuses on optimizing the meeting scheduling result for each participant in a mobile team by using user-specific preferences and information available on their devices. This negotiation is done in a distributed manner directly between the peers. In this paper we describe different approaches for the decision making strategy involving voting theory to balance out the different user preferences and availabilities. The weight of the votes from each participant can also be adjusted according to their importance or necessity in the given meeting. We also introduce briefly an approach to support distributed decision making strategies pervasively using a lightweight Web-based platform. To conclude the paper, we give our views on the future development directions and evaluation plans as well as extend the approach for other related domains.
Ligation of complement receptor 1 increases erythrocyte membrane deformability (2010)

Microbes as well as immune complexes and other continuously generated inflammatory particles are efficiently removed from the human circulation by red blood cells (RBCs) through a process called immune-adherence clearance. During this process, RBCs use complement receptor 1 (CR1, CD35) to bind circulating complement-opsonized particles and transfer them to resident macrophages in the liver and spleen for removal. We here show that ligation of RBC CR1 by antibody and complement-opsonized particles induces a transient Ca(++) influx that is proportional to the RBC CR1 levels and is inhibited by T1E3 pAb, a specific inhibitor of TRPC1 channels. The CR1-elicited RBC Ca(++) influx is accompanied by an increase in RBC membrane deformability that positively correlates with the number of preexisting CR1 molecules on RBC membranes. Biochemically, ligation of RBC CR1 causes a significant increase in phosphorylation levels of β-spectrin that is inhibited by preincubation of RBCs with DMAT, a specific casein kinase II inhibitor. We hypothesize that the CR1-dependent increase in membrane deformability could be relevant for facilitating the transfer of CR1-bound particles from the RBCs to the hepatic and splenic phagocytes.
Thermal transport in hard carbon prepared from fullerene (1996)

We report measurements of thermal conductivity in the 30 - 350 K range of hard fullerene-based carbon. The material has been prepared by pressure - temperature treatment of fullerene. It shows an unusual combination of high hardness and relatively high electrical conductivity. Its thermal conductivity is about at room temperature and decreases almost linearly in the investigated temperature range. Excellent linearity in a wide temperature range may arise from some sort of crystalline order in the transformed substance. Obtained data are compared with thermal properties of , glassy carbon and diamond. The applicability of recent theoretical models for explanation of recorded data is discussed.
A data-driven multitone echo canceller (2002)

A data-driven echo canceller for full-duplex data transmission with multitone modulation is presented. This echo canceller is shown not to be impaired by the eigenvalue-spread problems that are inherent in signal-driven echo cancellers, and to have numerical performance and cancellation range that equals, and in most cases exceeds, that of data-driven echo cancellers used in data transmission with baseband or quadrature amplitude modulation. The method makes use of frequency-domain updating, but with time-domain implementation of the canceller. It introduces no delay into the received signal path.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
[Inhibitory effect of TRPV6 silencing on prostate cancer cell line LNCaP in vitro]. (2010)

TRPV6-targeted siRNA can effectively inhibit the transcription of TRPV6 mRNA, inhibit the proliferation of LNCaP cells, arrest their cycles in the G0 and G1 phases, and induce their apoptosis.
Binding of erythromycin base to human plasma proteins. (1980)

The binding of erythromycin base (EB) to human plasma (HP) proteins was measured by equilibrium dialysis using EB-14C at approximately 0.5 microgram/ml in the plasma phase, expected therapeutic concentration. EB was 64.5 +/- 0.4% (mean +/- S.D.) bound to HP. The percentage of bound EB was linearly related to the logarithm of HP dilution. Physiological concentrations linearly related to the logarithm of HP dilution. Physiological concentrations of human serum albumin (HSA) and a1 acid glycoprotein (a1AGP) bound 8.7 +/- 1.6 and 54.5 +/- 0.6%, respectively, of the drug. No binding of EB to HDL or LDL or human gamma globulins was found. For HSA separately, EB binding followed a non-saturable phenomenon with n'K' = 100 +/- 5, while for a1AGP the binding was following a saturable phenomenon with n" = 1 +/- 0.045, K" = 35,000 +/- 5000 M-1. It can then be shown that, in human plasma, EB is only bound to those two proteins: firstly by computing the binding of EB to HSA and a1AGP with the previously indicated parameters, and secondly by measuring the binding of EB to HP. The computed curve fairly fits to the measured one. Interaction of EB with HP involved hydrophobic, ionic and hydrogen forces. Lower than 37 degrees C temperatures decreased EB binding. Significant competitive binding was demonstrated between EB and acetylsalicylic acid, furosemide, phenylbutazone, warfarin and bilirubin.
A network environment for computer-supported cooperative work (1987)

A second generation computer supported cooperative work system called Electronic Information Exchange System (EIES2) is described in this paper. The EIES2 communications environment allows users to network across geographical constraints using asynchronous or synchronous communications. The architecture of the network environment is decentralized, and is implemented using modern standards, and an easy-to-use user interface. At the heart of EIES2 is a high-level, object oriented pseudo machine which incorporates a distributed, communications-oriented database. The set of tools provided by the EIES2 communications environment is well suited for implementing group communication systems that have an extensive set of user features built into it. These tools are well suited to support the group communication model described by the AMIGO task force (IFIP 6.5 and ISO TC97/SC18/WG64). The EIES2 application layer protocols, using CCITT/ISO X.410 Remote Operations, support a distributed object oriented database.
Pilot scale high gradient magnetic filtration of steel mill wastewater (1976)

High gradient magnetic separators have been pilot tested for the removal of fine suspended solids from wastewaters of two Swedish steel mills. The first research into the use of these magnetic separators for wastewater treatment in the steel industry was conducted at the Massachusetts Institute of Technology under the sponsorship of the American Iron and Steel Institute [1] and Sala[2]. The results generated interest in exploring this technology further in certain Swedish and U.S. steel manufacturing companies. More extensive laboratory tests in Sweden led to on-site pilot testing at two mills in Sweden, NJA and Granges Nyby Bruk. The SALA-HGMS <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">TM</sup> Model 10-15-20 Automatic High Gradient Magnetic Separator was operated on feed to and overflow from scale pits fed by hot rolling mill cooling and scarfing waters. These waters contained up to 150 mg/l of suspended solids. Tests were conducted at magnetic field strengths from 0.1 to 0.9 T (1 to 9kG) and at flow velocities between 145 and 800 m/h. The results show that filtration efficiencies of over 90% are achieved with the Sala high gradient magnetic separator at process velocities many times higher than those in conventional treatment processes.
Reservoir riddles: suggestions for echo state network research (extended abstract) (2006)

Echo state networks (ESNs) offer a simple learning algorithm for dynamical systems. It works by training linear readout neurons that combine the signals from a random, fixed, excitable "dynamical reservoir" network. Often the method works beautifully, sometimes it works poorly - and we do not really understand why. This contribution discusses phenomena related to poor learning performance and suggests research directions. The common theme is to understand the reservoir dynamics in terms of a dynamical representation of the task's input signals.
Simultaneous separation of trace levels of germanium, antimony, arsenic, and selenium from an acid matrix by adsorbing colloid flotation (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimultaneous separation of trace levels of germanium, antimony, arsenic, and selenium from an acid matrix by adsorbing colloid flotationEric Heinen. DeCarlo, Harry. Zeitlin, and Quintus. FernandoCite this: Anal. Chem. 1981, 53, 7, 1104–1107Publication Date (Print):June 1, 1981Publication History Published online1 May 2002Published inissue 1 June 1981https://pubs.acs.org/doi/10.1021/ac00230a041https://doi.org/10.1021/ac00230a041research-articleACS PublicationsRequest reuse permissionsArticle Views160Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Speed control of two-inertia system by PI/PID control (2000)

The purpose of this paper is to develop systematic analysis and design methods for a two-inertia system. A conventional proportional-integral speed control system with a torsional load is redesigned, and the damping characteristic of the system is derived and analyzed. It is shown that the dynamic characteristic of the system strongly depends on the inertia ratio of load to motor. Three kinds of typical pole assignments with identical radius/damping coefficient/real part are applied and compared, and the merits of each pole-assignment design are concluded. Furthermore, for small inertia ratio, we present how to improve the damping of the system by a derivative feedback of motor speed.
A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug Candidate (2020)

TACC3, a transforming acidic coiled-coil (TACC) family member, is frequently upregulated in a broad spectrum of cancers, including breast cancer. It plays critical roles in protecting microtubule stability and centrosome integrity that is often dysregulated in cancers; therefore, making TACC3 a highly attractive therapeutic target. Here, we identified a new TACC3-targeting chemotype, BO-264, through the screening of in-house compound collection. Direct interaction between BO-264 and TACC3 was validated by using several biochemical methods, including drug affinity responsive target stability, cellular thermal shift assay, and isothermal titration calorimetry. BO-264 demonstrated superior antiproliferative activity to the two currently reported TACC3 inhibitors, especially in aggressive breast cancer subtypes, basal and HER2+, via spindle assembly checkpoint-dependent mitotic arrest, DNA damage, and apoptosis, while the cytotoxicity against normal breast cells was negligible. Furthermore, BO-264 significantly decreased centrosomal TACC3 during both mitosis and interphase. BO-264 displayed potent antiproliferative activity (∼90% have less than 1 μmol/L GI<sub>50</sub> value) in the NCI-60 cell line panel compromising of nine different cancer types. Noteworthy, BO-264 significantly inhibited the growth of cells harboring FGFR3-TACC3 fusion, an oncogenic driver in diverse malignancies. Importantly, its oral administration significantly impaired tumor growth in immunocompromised and immunocompetent breast and colon cancer mouse models, and increased survival without any major toxicity. Finally, TACC3 expression has been identified as strong independent prognostic factor in breast cancer and strongly prognostic in several different cancers. Overall, we identified a novel and highly potent TACC3 inhibitor as a novel potential anticancer agent, inducing spindle abnormalities and mitotic cell death.
Pulsed single-mode laser ionization of hyperfine levels of zirconium-91 (1988)

We identify a considerable improvement in proposed schemes for isotopic depletion of zirconium-91 on the basis of the atomic vapor laser isotope separation (AVLIS) method. The improvement lies in applying a single-longitudinal-mode dye laser for selective excitation of all hyperfine split levels of the ground state of zirconium-91. High-resolution laser-induced fluorescence spectroscopy of atomic beams of zirconium produced through laser vaporization–supersonic expansion has been used to identify transitions of zirconium with suitable hyperfine structure. Casimir magnetic-dipole and electric-quadrupole coupling constants and isotope shifts have been derived and are reported for five excited configurations. Suitable intermediate levels in a multistep resonance ionization pathway have been identified by two-color resonance ionization spectroscopy. Isotope depletion has been demonstrated on one ground-state-transition ( z F33∘←a F32at 593.7 nm) by using a specially constructed pulsed, single-longitudinal-mode dye-laser oscillator. Prospects and future directions in zirconium AVLIS are discussed.
Erosion Resistant Coatings for Polymer Matrix Composites in Propulsion Applications (2003)

Polymer Matrix Composites (PMCs) offer lightweight and frequently low cost alternatives to other materials in many applications. High temperature PMCs are currently used in limited propulsion applications replacing metals. Yet in most cases, PMC propulsion applications are not in the direct engine flow path since particulate erosion degrades PMC component performance and therefore restricts their use in gas turbine engines. This paper compares two erosion resistant coatings (SANRES and SANPRES) on PMCs that are useful for both low and high temperature propulsion applications. Collaborating over a multi-year period, researchers at NASA Glenn Research Center, Allison Advanced Developed Company, and Rolls-Royce Corporation have optimized these coatings in terms of adhesion, surface roughness, and erosion resistance. Results are described for vigorous hot gas/particulate erosion rig and engine testing of uncoated and coated PMC fan bypass vanes from the AE 3007 regional jet gas turbine engine. Moreover, the structural durability of these coatings is described in long-term high cycle fatigue tests. Overall, both coatings performed well in all tests and will be considered for applications in both commercial and defense propulsion applications.