gebhart/patrepeval huggingface dataset:
Systematic study of a series of highly fluorescent rod-shaped donor-acceptor systems (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSystematic study of a series of highly fluorescent rod-shaped donor-acceptor systemsR. M. Hermant, N. A. C. Bakker, T. Scherer, B. Krijnen, and Jan W. VerhoevenCite this: J. Am. Chem. Soc. 1990, 112, 3, 1214–1221Publication Date (Print):January 1, 1990Publication History Published online1 May 2002Published inissue 1 January 1990https://pubs.acs.org/doi/10.1021/ja00159a050https://doi.org/10.1021/ja00159a050research-articleACS PublicationsRequest reuse permissionsArticle Views653Altmetric-Citations141LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Practical Guide to First-Order Multiplet Analysis in 1H NMR Spectroscopy (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Practical Guide to First-Order Multiplet Analysis in 1H NMR SpectroscopyThomas R. Hoye, Paul R. Hanson, and James R. VyvyanCite this: J. Org. Chem. 1994, 59, 15, 4096–4103Publication Date (Print):July 1, 1994Publication History Published online1 May 2002Published inissue 1 July 1994https://pubs.acs.org/doi/10.1021/jo00094a018https://doi.org/10.1021/jo00094a018research-articleACS PublicationsRequest reuse permissionsArticle Views13230Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Exterior inspection of an aircraft using a Pan-Tilt-Zoom camera and a 3D scanner moved by a mobile robot : 2D image processing and 3D point cloud analysis (2016)

This thesis makes part of an industry oriented multi-partners project aimed at developing a mobile collaborative robot (a cobot), autonomous in its movements on the ground, capable of performing visual inspection of an aircraft during short or long maintenance procedures in the hangar or in the pre-flight phase on the tarmac. The cobot is equipped with sensors for realizing its navigation tasks as well as with a set of optical sensors which constitute the inspection head: an orientable Pan-Tilt-Zoom visible light camera and a three-dimensional scanner, delivering data in the format of two-dimensional images and three-dimensional point clouds, respectively. The goal of the thesis is to propose original approaches for processing 2D images and 3D clouds, with intention to make a decision with respect to the flight readiness of the airplane. We developed algorithms for verification of the aircraft items such as vents, doors, sensors, tires or engine as well as for detection and characterization of three-dimensional damages on the fuselage. We integrated a-priori knowledge on the airplane structure, notably numerical three-dimensional CAD model of the Airbus-A320. We argue that with investing effort to develop robust enough algorithms and with the help of existing optical sensors to acquire suitable data, we can come up with non-invasive, accurate, and time-efficient system for automatic airplane exterior inspection. The thesis work was placed in between two main requirements: develop inspection algorithms which could be as general as possible and also meet the specific requirements of an industry oriented project. Often, these two goals do not go along and the balance had to be made. On one side, we were aiming to design and assess the approaches that can be employed on other large structures, for ex. buildings, ships. On the other hand, writing source code for controlling sensors as well as integrating our whole developed source code with other modules on the real-time robotic system, were necessary in order to demonstrate the feasibility of our robotic prototype.
The Low Density Lipoprotein Receptor-related Protein Is a Motogenic Receptor for Plasminogen Activator Inhibitor-1 (2004)

Although plasminogen activator inhibitor-1 (PAI-1) is known to stimulate cell migration, little is known about underlying mechanisms. We show that both active and inactive (e.g. cleaved) PAI-1 can activate the Jak/Stat signaling system and stimulate cell migration in chemotaxis, haptotaxis, chemokinesis, and wound healing assays. Moreover, antibodies to the LDL receptor-related protein (LRP) and an LRP antagonist (RAP) blocked these motogenic effects of PAI-1, while a PAI-1 mutant that did not bind to LRP failed to activate the Jak/Stat signaling pathway or to stimulate cell migration. PAI-1 had no chemotactic effect on LRP-deficient cells. These results indicate that LRP is a signaling molecule, that it mediates the migration-promoting activity of PAI-1, and that this activity does not require intact, biologically active PAI-1. Activation of this LRP-dependent signaling pathway by PAI-1 may begin to explain how the inhibitor stimulates cell migration in a variety of normal and pathological processes.
Bacterial and plant HAD enzymes catalyse a missing phosphatase step in thiamin diphosphate biosynthesis (2015)

The penultimate step of thiamin diphosphate (ThDP) synthesis in plants and many bacteria is dephosphorylation of thiamin monophosphate (ThMP). Non-specific phosphatases have been thought to mediate this step and no genes encoding specific ThMP phosphatases (ThMPases) are known. Comparative genomic analysis uncovered bacterial haloacid dehalogenase (HAD) phosphatase family genes (from subfamilies IA and IB) that cluster on the chromosome with, or are fused to, thiamin synthesis genes and are thus candidates for the missing phosphatase (ThMPase). Three typical candidates (from Anaerotruncus colihominis, Dorea longicatena and Syntrophomonas wolfei) were shown to have efficient in vivo ThMPase activity by expressing them in an Escherichia coli strain engineered to require an active ThMPase for growth. In vitro assays confirmed that these candidates all preferred ThMP to any of 45 other phosphate ester substrates tested. An Arabidopsis thaliana ThMPase homologue (At4g29530) of unknown function whose expression pattern and compartmentation fit with a role in ThDP synthesis was shown to have in vivo ThMPase activity in E. coli and to prefer ThMP to any other substrate tested. However, insertional inactivation of the At4g29530 gene did not affect growth or the levels of thiamin or its phosphates, indicating that Arabidopsis has at least one other ThMPase gene. The Zea mays orthologue of At4g29530 (GRMZM2G035134) was also shown to have ThMPase activity. These data identify HAD genes specifying the elusive ThMPase activity, indicate that ThMPases are substrate-specific rather than general phosphatases and suggest that different evolutionary lineages have recruited ThMPases independently from different branches of the HAD family.
Expression of the hemoglobin scavenger receptor (CD163/HbSR) as immunophenotypic marker of monocytic lineage in acute myeloid leukemia (2003)

The hemoglobin-haptoglobin scavenger receptor (CD163/HbSR) is a monocyte/macrophage-restricted transmembrane protein of the scavenger receptor cysteine-rich family.[1][1] Antigen expression is related to monocyte/macrophage differentiation, with weak expression on peripheral blood monocytes and
Analysis of Polypurine Tract-associated DNA Plus-strand Priming in Vivo Utilizing a Plant Pararetroviral Vector Carrying Redundant Ectopic Priming Elements (1998)

Initiation of DNA plus-strand synthesis in most reverse-transcribing elements requires primer generation by reverse transcriptase-associated RNase H at one or more template polypurine tracts (PPTs). We have exploited infectious clones of the plant pararetrovirus cauliflower mosaic virus carrying redundant ectopic plus-strand priming elements to study priming in vivo. Ectopic priming generated an additional discontinuity in progeny virion DNA during infection of plants. We found that altering the length of the 13-base pair PPT by +/-25% significantly reduced priming efficiency. A short pyrimidine tract 5' to the PPT, highly conserved among diverse reverse-transcribing elements, was shown to play an important role in PPT recognition in vivo. The predominant DNA plus-strand 5' end remained 3 nucleotides from the PPT 3' end in mutant primers that were longer or shorter than the wild-type primer. Use of an ectopic redundant primer to study replication-dependent priming was validated by demonstrating that it could rescue infectivity following destruction of the wild-type priming elements. We propose a model for plant pararetroviral plus-strand priming in which pyrimidines enhance PPT recognition during polymerase-dependent RNase H cleavages, and suggest that fidelity of primer maturation during polymerase-independent cleavages involves PPT length measurement and 3' end recognition by RNase H.
Carotenoid and fatty acid metabolism in light‐stressed <i>Dunaliella salina</i> (2010)

beta-Carotene is overproduced in the alga Dunaliella salina in response to high light intensities. We have studied the effects of a sudden light increase on carotenoid and fatty acid metabolism using a flat panel photobioreactor that was run in turbidostat mode to ensure a constant light regime throughout the experiments. Upon the shift to an increased light intensity, beta-carotene production commenced immediately. The first 4 h after induction were marked by constant intracellular levels of beta-carotene (2.2 g LCV(-1)), which resulted from identical increases in the production rates of cell volume and beta-carotene. Following this initial phase, beta-carotene productivity continued to increase while the cell volume productivity dropped. As a result, the intracellular beta-carotene concentration increased reaching a maximum of 17 g LCV(-1) after 2 days of light stress. Approximately 1 day before that, the maximum beta-carotene productivity of 30 pg cell(-1) day(-1) (equivalent to 37 mg LRV(-1) day(-1)) was obtained, which was about one order of magnitude larger than the average productivity reported for a commercial beta-carotene production facility, indicating a vast potential for improvement. Furthermore, by studying the light-induced changes in both beta-carotene and fatty acid metabolism, it appeared that carotenoid overproduction was associated with oil globule formation and a decrease in the degree of fatty acid unsaturation. Our results indicate that cellular beta-carotene accumulation in D. salina correlates with accumulation of specific fatty acid species (C16:0 and C18:1) rather than with total fatty acid content.
Responsible agent behavior: a distributed computing perspective (2000)

Software agents that are autonomous, communicative, and possibly intelligent processes raise new questions for developers of distributed systems. Specifically, what is responsible agent behavior, and who, as the owner, is legally responsible for it? The answers involve an understanding of human-agent interaction, agent-oriented middleware, and social behavior. Some software agents will have a sufficiently large number of internal states to be capable of seemingly intelligent behavior. Hence, an agent's future external behavior cannot be guaranteed on the basis of its past behavior, even if that behavior has been monitored over time. Complete compliance tests of intelligent agents, therefore, may not be achievable because of the (possibly) large number of internal states. Thus, the best we can say is that an agent has not exhibited noncompliant behavior yet. Communication between agents implies a contract between owners, and the complexity of agents implies possibly unpredictable behavior. Therefore, an appropriate legal framework is required to underwrite the consequences of communicative actions and to provide safeguards against unlawful activities. The legal implications of agent technology require new ways of thinking about working with an agent, new requirements for agent-oriented middleware, and additional types of social behavior to be considered when designing a multiagent system.
Multimodal 'eyes-free' interaction techniques for wearable devices (2003)

Mobile and wearable computers present input/output prob-lems due to limited screen space and interaction techniques. When mobile, users typically focus their visual attention on navigating their environment - making visually demanding interface designs hard to operate. This paper presents two multimodal interaction techniques designed to overcome these problems and allow truly mobile, 'eyes-free' device use. The first is a 3D audio radial pie menu that uses head gestures for selecting items. An evaluation of a range of different audio designs showed that egocentric sounds re-duced task completion time, perceived annoyance, and al-lowed users to walk closer to their preferred walking speed. The second is a sonically enhanced 2D gesture recognition system for use on a belt-mounted PDA. An evaluation of the system with and without audio feedback showed users' ges-tures were more accurate when dynamically guided by au-dio-feedback. These novel interaction techniques demon-strate effective alternatives to visual-centric interface de-signs on mobile devices.
Hardware implementation of an interference canceller for IDMA wireless communications (2013)

Due to the increasing demand for machine-to-machine (M2M) communication, a wireless system which realizes simultaneous communication of small-sized packets for a large number of users is requested. Interleave division multiple access (IDMA) is known to have superior user detection performance in communication with a large number of users. This paper reports the hardware implementation of an interference canceller for IDMA communication systems. The conventional architecture suffers from low utilization efficiency in interleaving/de-interleaving. The proposed architecture improves the utilization efficiency by applying dual frame processing in the interference canceller. The proposed architecture has reduced circuit area and power dissipation by 25% and 41%, respectively.
Mechanical design and control of inflatable robotic arms for high positioning accuracy (2017)

In recent years, inflatable robotic arms have been developed so that physical contact with humans and working environments could be performed safety. In industry, there is a growing demand for safe industrial robots to collaborate with people and work in various environments. In general, however, the positioning accuracy of inflatable robotic arms has not been discussed. This paper proposes an inflatable link structure and a non-inflatable joint structure that could realize a high positioning accuracy for such robotic arms. This paper experimentally demonstrates that these structures can improve positioning accuracy. In addition to these structures, the joint torque characteristics of the inflatable robotic arms were investigated. In order to perform accurate motion control, a visual feedback control method was introduced for inflatable robotic arms. The mechanism and control system used in this paper can improve the positioning accuracy performance of inflatable robots. A 2-DOF inflatable robotic arm and a camera system were found to be able to achieve a high positioning accuracy (i.e. less than 1 mm).
Toxoplasmacidal activity of macrophages activated by recombinant major surface antigen (P30) of Toxoplasma gondii (1991)

Recombinant major surface antigen (P30), which was produced as a glutathione S-transferase (EC 2.5.1.18) fusion protein of Toxoplasma gondii, was found to be able to activate macrophages to kill T. gondii in vitro. The macrophage activation was due to P30 in the fusion protein, not to glutathione S-transferase.
<i>In Vitro</i>Ischemia Promotes Glutamate-Mediated Free Radical Generation and Intracellular Calcium Accumulation in Hippocampal Pyramidal Neurons (1997)

Ischemia-induced cell damage studies have revealed a complex mechanism that is thought to involve glutamate excitotoxicity, intracellular calcium increase, and free radical production. We provide direct evidence that free radical generation occurs in rat CA1 pyramidal neurons of organotypic slices subjected to a hypoxic-hypoglycemic insult. The production of free radicals is temporally correlated with intracellular calcium elevation, as measured by injection of fluo-3 in individual pyramidal cells, using patch electrodes. Free radical production (measured as changes in the fluorescence emission of dihydrorhodamine 123) peaked during reoxygenation and paralleled rising intracellular calcium. Electrophysiological whole-cell recordings revealed membrane potential depolarization and decreased input resistance during the ischemic insult. Glutamate receptor blockade resulted in decreased free radical production and markedly diminished intracellular calcium accumulation, and prevented neuronal depolarization and input resistance decrease during the ischemic episode. These results provide evidence for a direct involvement of glutamate in oxidative damage resulting from ischemic episodes.
Free-Radical-Mediated Conjugate Additions. Enantioselective Synthesis of Butyrolactone Natural Products:  (−)-Enterolactone, (−)-Arctigenin, (−)-Isoarctigenin, (−)-Nephrosteranic Acid, and (−)-Roccellaric Acid (2002)

Lewis acid-mediated conjugate addition of alkyl radicals to a differentially protected fumarate 10 produced the monoalkylated succinates with high chemical efficiency and excellent stereoselectivity. A subsequent alkylation or an aldol reaction furnished the disubstituted succinates with syn configuration. The chiral auxiliary, 4-diphenylmethyl-2-oxazolidinone, controlled the stereoselectivity in both steps. Manipulation of the disubstituted succinates obtained by alkylation furnished the natural products (-)-enterolactone, (-)-arctigenin, and (-)-isoarctigenin. The overall yields for the target natural products were 20-26% over six steps. Selective functionalization of the disubstituted succinates obtained by aldol condensation gave the paraconic acid natural products (-)-nephrosteranic acid (8) and (-)-roccellaric acid (9). The overall yield of the natural products 8 and 9 over four steps was 53% and 42%, respectively.
Improved Output Power of InGaN LEDs by Lateral Overgrowth on Si-Implanted n-GaN Surface to Form Air Gaps (2012)

In this paper, air gaps were embedded in the n-GaN layer to improve light output power of InGaN-based light-emitting diodes (LEDs). Si ions (Si±28) were implanted on the n-GaN surface, causing a lattice constant disorder. Therefore, the GaN grown on the Si-implanted areas had a lower growth rate than the implantation-free regions. Without using a dielectric thin film, lateral epitaxial overgrowth technique was used to form air gaps above the implanted regions and below the active layers of InGaN LEDs. We proposed the growth mechanisms of GaN layer on the Si-implanted GaN templates and characterized the InGaN-based LEDs with embedded air gaps array. With a 20-mA current injection, experimental results indicate that light output power (LOP) of the proposed LEDs was enhanced by 36%, compared with those of the conventional LEDs. This enhancement can be attributed to the light scattering at the textured GaN/gap interfaces to increase the effective light escape cone in the LEDs. Based on ray tracing simulation, if the height and the width of bottom of gaps were increased to 3 μm, the Lop could be enhanced over 70%.
Impact activation of chemical reactions (1983)

Thin films of a number of substances were exposed to molecular beams covering the energy range 0.03--5000 eV. (AIP)
Downlink Spatial Scheduling with Mutual Interference Cancellation in Multiuser MIMO Systems (2006)

This paper presents downlink spatial scheduling which nullifies interference among multiplexed signals perfectly in multiuser MIMO systems. Under the base station's zero-forcing transmit beamforming, each terminal can receive packet of interest without interference from the other multiplexed packets. The scheduling algorithm successively selects appropriate terminals for packet transmission in the presence of already selected packets. We show that the downlink spatial scheduler is equivalent to the virtual uplink spatial scheduler in terms of received signal characteristics. Applying the uplink scheduling concept to downlink, the downlink spatial scheduler achieves much higher system throughput than the system without spatial scheduling. Also, it is shown that the spatial scheduler has similar system throughput in uplink and downlink
Synthesis of thiolated chitosan and preparation nanoparticles with sodium alginate for ocular drug delivery. (2012)

TCS-SA NPs have better delivery capability, suggesting they have good potential for ocular drug delivery applications.
Demonstration of the high-frequency optical heterodyne technology using near-field fiber-optic probes (1999)

We demonstrate the use of near-field fiber-optic probes in optical heterodyne characterization of high-speed devices. The submicron-size optical beam obtained from the fiber-optic probe was employed to selectively excite a small local portion of the active region of the device. Optical heterodyne measurements on heterojunction bipolar transistors were conducted at 1550 nm with a difference frequency of 100 GHz. The significant response of the device with a signal-to-noise ratio of 30 dB was observed. The dc and the ac photoresponses were also measured as a function of the distance between the fiber-optic probe and the device under test. The data showed clearly distinguishable regimes of near- and far-field operation. The high-frequency near-field optical heterodyne technique as explored in this letter provides us with capabilities that can be effectively utilized in the field of optical millimeter-wave interaction in ultrafast devices.