gebhart/patrepeval huggingface dataset:
Reactogenicity and Immunogenicity of a Quadrivalent Combined Meningococcal Polysaccharide Vaccine in Children (1986)

Journal Article Reactogenicity and Immunogenicity of a Quadrivalent Combined Meningococcal Polysaccharide Vaccine in Children Get access Martha L. Lepow, Martha L. Lepow Department of Pediatrics, Albany Medical College, Albany, New York; and Connaught Laboratories, Swiftwater, Pennsylvania Please address requests for reprints to Dr. Martha L. Lepow, Albany Medical College, Department of Pediatrics, Room KN-430, 47 New Scotland Avenue, Albany, New York 12208. Search for other works by this author on: Oxford Academic PubMed Google Scholar Judy Beeler, Judy Beeler Department of Pediatrics, Albany Medical College, Albany, New York; and Connaught Laboratories, Swiftwater, Pennsylvania Search for other works by this author on: Oxford Academic PubMed Google Scholar Martin Randolph, Martin Randolph Department of Pediatrics, Albany Medical College, Albany, New York; and Connaught Laboratories, Swiftwater, Pennsylvania Search for other works by this author on: Oxford Academic PubMed Google Scholar Joel S. Samuelson, Joel S. Samuelson Department of Pediatrics, Albany Medical College, Albany, New York; and Connaught Laboratories, Swiftwater, Pennsylvania Search for other works by this author on: Oxford Academic PubMed Google Scholar William A. Hankins William A. Hankins Department of Pediatrics, Albany Medical College, Albany, New York; and Connaught Laboratories, Swiftwater, Pennsylvania Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 154, Issue 6, December 1986, Pages 1033–1036, https://doi.org/10.1093/infdis/154.6.1033 Published: 01 December 1986 Article history Received: 01 April 1986 Revision received: 03 July 1986 Published: 01 December 1986
Joint suppression of phase noise and CFO by block type pilots (2009)

MIMO (multiple input multiple output) system has been used to for communication capacity enhancement. Also, the single carrier frequency division multiple access (SC-FDMA) has very low PAPR (peak to average power ratio) property. However, SC-FDMA system is very sensitive to phase noise (PN) and carrier frequency offset (CFO), so that CPE (common phase error) and ICI (inter-subcarrier interference) in the received signal degrade the system performance seriously. Therefore, the suppression of influences from CFO and phase noise is of great importance. In this paper, we analyze the interference effects caused by phase noise and CFO in MIMO SC-FDMA system with SC-SFBC (single carrier -space frequency block coding). Next, a new ICI suppression method is proposed to overcome the ICI by block type pilot that is very suitable for SC-FDMA. The computer simulations show that the system performance is significantly improved by the proposed method.
A propagation of a stress wave and an interaction with a free surface (2004)

We make a new SPH (Smoothed Particle Hydrodynamics) code based on MLS (Moving Least Squares) method to analyze the dynamics of stress wave. The new code is examined by the simulation of an elastic wave interacted with a free surface. The result using the new code is compared with both the result of SPH and the experimental results of the model blasting using the electric detonator. The elastic wave emanates from the charge hole and interacts with the free surface. Propagation of elastic wave and reflection at the free surface are well simulated by the new method compared with SPH method.
New methods and reagents in organic synthesis. 67. A general synthesis of derivatives of optically pure 2-(1-aminoalkyl)thiazole-4-carboxylic acids (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew methods and reagents in organic synthesis. 67. A general synthesis of derivatives of optically pure 2-(1-aminoalkyl)thiazole-4-carboxylic acidsYasumasa Hamada, Makoto Shibata, Tsuneyuki Sugiura, Shinji Kato, and Takayuki ShioiriCite this: J. Org. Chem. 1987, 52, 7, 1252–1255Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April 1987https://pubs.acs.org/doi/10.1021/jo00383a014https://doi.org/10.1021/jo00383a014research-articleACS PublicationsRequest reuse permissionsArticle Views2943Altmetric-Citations176LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The pursuit of electrically-driven organic semiconductor lasers (2014)

Organic semiconductors have many favourable and plastic-like optical properties that are promising for the development of low energy consuming laser devices. Although optically-pumped organic semiconductor lasers have been demonstrated since the early days of lasers, electrically-driven organic lasers have not been realized and have become one of the greatest challenges in the fields of physics, chemistry and materials science. This article highlights the recent progress in the development of electroluminescent devices, as well as new types of materials with the aim of realizing the first electrically-driven organic semiconductor laser.
Optimized Structure of the Traffic Flow Forecasting Model With a Deep Learning Approach (2016)

Forecasting accuracy is an important issue for successful intelligent traffic management, especially in the domain of traffic efficiency and congestion reduction. The dawning of the big data era brings opportunities to greatly improve prediction accuracy. In this paper, we propose a novel model, stacked autoencoder Levenberg-Marquardt model, which is a type of deep architecture of neural network approach aiming to improve forecasting accuracy. The proposed model is designed using the Taguchi method to develop an optimized structure and to learn traffic flow features through layer-by-layer feature granulation with a greedy layerwise unsupervised learning algorithm. It is applied to real-world data collected from the M6 freeway in the U.K. and is compared with three existing traffic predictors. To the best of our knowledge, this is the first time that an optimized structure of the traffic flow forecasting model with a deep learning approach is presented. The evaluation results demonstrate that the proposed model with an optimized structure has superior performance in traffic flow forecasting.
Nonlinear excitations in pernigraniline, the oxidized form of polyaniline (1989)

The electronic structure of fully oxidized polyaniline, pernigraniline, is investigated in the framework of the Su-Schrieffer-Heeger Hamiltonian, making use of an original renormalization technique. Among the family of polyanilines, pernigraniline is the only form to possess a degenerate ground state. It is shown to accomodate elementary excitations of soliton and polaron types having remarkable properties, in some instances markedly different from those predicted for the so-called AB polymer. Nonlinear optical properties of the material are expected to be important.
Electromagnetic Wave Scattering from an Active Corrugated Structure (1972)

This paper studies the scattering of a plane wave by an active corrugated structure in which each slot region is connected to a microwave solid-state amplifier. Consequently, not only are we able to control the phase of the reflected wave but also its power gain. An exact solution to this problem has been obtained by the residue calculus method under the assumption that only the TEM wave propagates and is amplified in the slot region. Numerical results are presented for illustrating the scattering properties as a function of the slot dimension and the amplifier gain. An approximate but much simplified analytical expression for the reflection coefficient is derived and it should be found useful in other scattering problems (such as the design of a reflector antenna) by the ray-tracing method. A related problem of surface wave propagation on the active corrugated structure and its potential application as a high-power amplifier are also discussed.
Kinase suppressor of Ras 2 is involved in regulation of cell proliferation and is up-regulated in human invasive ductal carcinomas of breast. (2010)

Our findings propose KSR2 as a new marker of immortalization, which has an impact on cell proliferation.
A Direct Repeat Is a Hotspot for Large-Scale Deletion of Human Mitochondrial DNA (1989)

Kearns-Sayre syndrome (KSS) and progressive external ophthalmoplegia (PEO) are related neuromuscular disorders characterized by ocular myopathy and ophthalmoplegia. Almost all patients with KSS and about half with PEO harbor large deletions in their mitochondrial genomes. The deletions differ in both size and location, except for one, 5 kilobases long, that is found in more than one-third of all patients examined. This common deletion was found to be flanked by a perfect 13-base pair direct repeat in the normal mitochondrial genome. This result suggests that homologous recombination deleting large regions of intervening mitochondrial DNA, which previously had been observed only in lower eukaryotes and plants, operates in mammalian mitochondrial genomes as well, and is at least one cause of the deletions found in these two related mitochondrial myopathies.
DNA Modifications: Function and Applications in Normal and Disease States (2014)

Epigenetics refers to a variety of processes that have heritable effects on gene expression programs without changes in DNA sequence. Key players in epigenetic control are chemical modifications to DNA, histone, and non-histone chromosomal proteins, which establish a complex regulatory network that controls genome function. Methylation of DNA at the fifth position of cytosine in CpG dinucleotides (5-methylcytosine, 5mC), which is carried out by DNA methyltransferases, is commonly associated with gene silencing. However, high resolution mapping of DNA methylation has revealed that 5mC is enriched in exonic nucleosomes and at intron-exon junctions, suggesting a role of DNA methylation in the relationship between elongation and RNA splicing. Recent studies have increased our knowledge of another modification of DNA, 5-hydroxymethylcytosine (5hmC), which is a product of the ten-eleven translocation (TET) proteins converting 5mC to 5hmC. In this review, we will highlight current studies on the role of 5mC and 5hmC in regulating gene expression (using some aspects of brain development as examples). Further the roles of these modifications in detection of pathological states (type 2 diabetes, Rett syndrome, fetal alcohol spectrum disorders and teratogen exposure) will be discussed.
Electromagnetic Levitation Melting of Large Conduction Loads (1977)

A new kind of levitator has been developed that allows the levitation melting of large metallic loads. The new technique has been successfully applied to achieve the levitation melting of 1-kg aluminum spheres. The technique and design procedures described here are also applicable to loads of other metals and of different shape or size. Unlike the models previously available, the new levitators do not rely on the effect of surface tension. Instead, several magnetic fields of different frequencies are properly shaped and oriented to produce adequate pressure distributions as well as to ensure the necessary surface and bulk stability.
Removal of Organic Compounds from Aqueous Solutions by the Electrochemical Reactor with Fluidized-bed Carbon Layer (2000)

A method for potential-dependant separation by an electrochemical reactor based on flow-through mode with a fluidized-bed carbon layer was described. In this method, activated synthetic carbons were used as a fluidized-bed electrode. Influence of surface acidic functional groups, applied potential and pH of surrounding electrolyte on the adsorption capacity of the activated carbons for benzoic acid and phenol was studied. Anodic polarization of the activated carbons was found to result in increase in adsorption capacity of the activated carbons for benzoic acid and entire oxidation of phenol. Application of cathodic external potential allowed regeneration of spent activated carbons. A practically available technique for developing and regenerating materials for effective electrochemical separation suitable for further application in electro adsorption was described in this work.
Alarm Reliability in Vibration Monitoring of Ball Bearing Seizure due to Lubrication Scarcity. Comparison between Kalman Filter and Exponentially Weighted Moving Average. (1993)

This paper examines alarm reliability based on the vibration monitoring of rotary machinery. Two procedures for diagnosing bearing condition are compared experimentally. One is the Kalman filter combined with Bayes' theorem and the other is the exponentially weighted moving average method. In the experiment, the rotor is operated at a constant speed and the vibration level is monitored. Increased vibration due to bearing seizure is detected by the methods mentioned above. The results show that 1) the moving average method can detect relatively faster than the method using the kalman filter but sometimes leads to a false alarm, and 2) in monitoring using the Kalman filter, no false alarm is observed, which means that higher alarm reliability can be obtained by the Kalman filter.
Construction and Launching (1933)

Construction and LaunchingThe announcement that a comparatively ob scure boat yard, located on the upper Mississippi, remote from the sea, had secured the contract for building an important naval vessel came as a dis tinct surprise, not only to eastern ship-builders but to many citizens of Iowa.That the Dubuque company meant business, there could be no doubt.Bonds were promptly filed for the "timely and successful completion of the boat", and the con tract was signed on October 8, 1891, for a stipu lated sum of $113,500.Under the terms of the contract "she must be able to make not less than twenty-four knots an hour on her trial trip" under the supervision of the Navy Department.It was no secret that the contract price was probably less than the actual cost of construction would be, but since the government had offered a bonus of $15,000 for each knot the boat was able to make in excess of the minimum requirement, it was hoped, by exceedingly careful construction, to make up this deficit by means of the bonus.In deed, the contractor confidently expected "that she will make at least twenty-eight knots an hour on her trial trip," thus assuring her builders an ad-
64 Channel All Optical Deployable Acoustic Array (1997)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text A. R. Davis, C. K. Kirkendall, A. Dandridge, and A. D. Kersey, "64 Channel All Optical Deployable Acoustic Array," in 12th International Conference on Optical Fiber Sensors, Vol. 16 of 1997 OSA Technical Digest Series (Optica Publishing Group, 1997), paper OFA6. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Antiinflammatory activity of some 2,3-dihydrobenzofuran-5-acetic acids and related compounds (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntiinflammatory activity of some 2,3-dihydrobenzofuran-5-acetic acids and related compoundsNoriyasu Hirose, Shizuo Kuriyama, Yoshinori Kato, and Shoji ToyoshimaCite this: J. Med. Chem. 1976, 19, 2, 303–308Publication Date (Print):February 1, 1976Publication History Published online1 May 2002Published inissue 1 February 1976https://pubs.acs.org/doi/10.1021/jm00224a020https://doi.org/10.1021/jm00224a020research-articleACS PublicationsRequest reuse permissionsArticle Views143Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis of Zeolite Monolith with Hierarchical Micro/Macropores by Ice-Templating and Steam-Assisted Crystallization (2013)

Zeolite monolith was synthesized by ice-templating and steam-assisted crystallization (SAC) by using a structure-directing agent (SDA). The precursor silica gel was prepared by applying ice-templating to the hydrogels synthesized from colloidal silica. Sodium aluminate (NaAlO2) was supported in the precursor by impregnation to prepare zeolite monolith. Silicalite monolith or zeolite monolith with three-dimensionally interconnected macropores was synthesized by SAC of the precursor by using tetrapropylammonium hydroxide as SDA. The monolith had the continuous macropores, and the surface of these macropores was densely covered with zeolite crystals. The crystals were identified as MFI-type by XRD and had a well ordered microporous structure. Since the macropores, which were formed by ice-templating, were directly connected to the micropores of the synthesized zeolite crystals, the synthesized zeolite monolith had the hierarchical structure of macropores and micropores. The macroporous structure of monolith could be controlled by the freezing conditions because the macropore size became large with the decrease in freezing rate of hydrogels. The BET surface area and the degree of crystallinity of zeolite monolith wereincreased up to 347 m2/g and 89 % by SAC. When the zeolite monolith was synthesized by changing the Si/Al ratio, the crystallization rate increased with the increase in Si/Al ratio, and the hydrophilic or hydrophobic property was also controlled by choosing the Si/Al ratio.
Potency determination of factor <scp>VIII</scp> and factor <scp>IX</scp> for new product labelling and postinfusion testing: challenges for caregivers and regulators (2015)

A workshop organized by the European Medicines Agency and the European Directorate for the Quality of Medicines and HealthCare was held in London, UK on November 28-29, 2013, to provide an overview of the current knowledge of the characterization of new factor VIII (FVIII) and factor IX (FIX) concentrates with respect to potency assays and testing of postinfusion material. The objective was to set the basis for regulatory authorities' discussion on the most appropriate potency assay for the individual products, and European Pharmacopoeia (Ph. Eur.) discussion on whether to propose revision of the Ph. Eur. monographs with respect to potency assays in the light of information on new FVIII and FIX concentrates. The workshop showed that for all products valid assays vs. the international concentrate standards were obtained and potency could be expressed in International Units. The Ph. Eur. chromogenic potency assay gave valid assay results which correlate with in vivo functionality of rFVIII products. For some modified rFVIII products and all modified rFIX products, one-stage clotting assay methods result in different potencies depending on the activated partial thromboplastin time reagent. As a consequence, monitoring of patients' postinfusion levels is challenging but it was pointed out that manufacturers are responsible for providing the users with appropriate information for use and laboratory testing of their product. Strategies to avoid misleading determination of patents' plasma levels, e.g. information on suitable assays, laboratory standards or correction factors were discussed.
Energy transmission of switched‐capacitor circuit and application to dc‐dc converter (1991)

Abstract The switched capacitor (SC) circuit has been applied to analog signal processing, but few reports have been made on the application to power circuit. Recently, a report has been made on the dc‐dc converter using the SC circuit, but the circuit still has a number of problems, e.g., the loss due to the switching element or equivalent resistance of the SC circuit, the output ripple and the noise. From such a viewpoint, this paper presents first the theoretical and experimental investigations on the energy loss, energy transmission efficiency and output power of the dc‐dc converter using the basic SC circuit. Based on that result, dc‐dc converters are considered using a series‐parallel switching SC circuit with more than one capacitor. It is seen as a result that the loss due to the equivalent resistance is inevitable, even if ideal switching elements or capacitors are used in those SC circuits. As a means to cope with this problem, the dc‐dc converter using a new SC circuit is proposed, where the zero‐voltage switching mechanism is employed using a high‐frequency supply and the peak‐detector circuit. It is shown theoretically that the loss due to the equivalent resistance is not produced in principle in the proposed SC circuit. A result of experiment is shown with a drastic improvement.
[Risk assessment of factors related to lactation of breast-feeding women by multichotomous logistic regression with stepwise procedure]. (1989)

Based on Dubin and Pasternack's solution of parsimonious parameters, the authors proposed a procedure of stepwise selection of factors for establishing the Multichotomous logistic regression "best" model. Score statistic was used to select factors into model. Ratio of likelihood function was used to eliminate factors from model. The data of lactation from 129 breast-feeding women living in rural area have been analysed by the procedure. It showed that the first breast-feeding to the newborn of over 48 hours from her childbirth has negative effect while good appetite has positive effect on milk secretion. The epidemiological meaning of parameters estimated from the data was illustrated in detail.