gebhart/patrepeval huggingface dataset:
Visual Structure Analysis of Flow Charts in Patent Images. (2012)

This report presents the work carried out for the ow chart recognition task in the course of the CLEF-IP 2012 competition. The goal is to obtain structural information of ow charts based on the vi- sual content of the images. To this end, for each
Follicular development in the neonatal mouse ovary; effect of epidermal growth factor (1981)

The growth of the ovary has been studied in the mouse after administration of epidermal growth factor (EGF). Newborn females injected daily with EGF for the first 5 days of life showed a retardation of ovarian development. The number of follicles in the resting pool (small follicles) was significantly greater than in control animals and there were fewer growing follicles at more advanced stages of development (types 3b and 4). The percentage of mitotic figures in the follicular and surface epithelia of the ovary and the epithelium of the extra-ovarian rete was also significantly reduced after EGF. The results indicate that EGF may inhibit rather than promote the growth of follicles in the neonatal mouse ovary in vivo.
4D visualisation development: Real life case studies (2002)

Visual 4D planning and scheduling technique that combines 3D CAD models with construction activities (time) has proven benefits over traditional tools, such as bar charts and network diagrams. In 4D models, project participants can effectively visualise and analyse problems regarding sequential, spatial, and temporal aspects of construction schedules. As a consequence, more robust schedules can be generated and hence reduce reworks and improve productivity. Currently, there are several working research prototypes and commercial software that have ability to generate 4D model. However, two major issues arise regarding the current 4D development approaches and the use of commercial software. These are the limited feasibility to large and complex projects, and inflexibility to incorporate more construction problems (nD modelling) especially for process constraints such as spatial conflicts, and availability of information and resources. As a part of the VIRCON project, an EPSRC funded research, this paper introduces a pragmatic approach to develop extensible 4D visualisation using two real life case studies. ProVis, a 4D simulator, was developed using Visual Basic for Applications (VBA), accessing the integrated products and processes from the VIRCON database and produces 4D model in the AutoCAD environment. This 4D tool is also integrated with a Critical Space Analysis (CSA) tool (another VIRCON tool) and is able to visualise spatial overload of the construction site. The paper details 4D development process based on the proposed approach and discusses efforts spent to convert general project information (2D drawings and schedules) to 4D models. It is concerned that a little additional effort was needed to develop the extensible 4D model based on the proposed approach. In addition, no commercial 4D software was used to achieve the visualisation process.
MOT: memory online tracing of Web information system (2005)

With advances in World-Wide Web applications and technologies, research on measurement and modeling of Internet and Web-based information systems has become increasingly important This paper focuses on continuously monitoring Web traffic by packet sniffing on high-speed links, which is the foundation of analyzing theoretical models of Web characteristics and evolvement. The author presents MOT, a memory online tracing system of Web traffic. MOT parses all packets in memory directly without involving unnecessary I/0 operations with magnetic disks to enhance the system performance. Event-driven design pattern and several other techniques are adopted in MOT to overcome the difficulties of buffering huge volume of traffic. MOT provides a fast, accurate and safe way to obtain the source data for many Web-related studies.
MVS data services (1989)

The IBM Enterprise Systems Architecture/370™ vastly increases the potential virtual addressability available to both system and application programs. The I/O model and the application model of permanent data are discussed to illustrate how large virtual addressability can be used to simplify application programs and improve performance. New MVS services that exploit the architecture are described. Also described are data window services, which are callable from high-level languages and provide the capability to manage very large permanent and temporary objects in virtual storage.
Statistical Timing Analysis Using Bounds (2003)

The growing impact of within-die process variation has created the need for statistical timing analysis, where gate delays are modeled as random variables. Statistical timing analysis has traditionally suffered from exponential run time complexity with circuit size, due to the dependencies created by reconverging paths in the circuit. In this paper we propose a new approach to statistical timing analysis which uses statistical bounds. First, we provide a formal definition of the statistical delay of a circuit and derive a statistical timing analysis method from this definition. Since this method for finding the exact statistical delay has exponential run time complexity with circuit size, we also propose a new method for computing statistical bounds which has linear run time complexity. We prove the correctness of the proposed bounds. Since we provide both a lower and upper bound on the true statistical delay we can determine the quality of the bounds. The proposed methods were implemented and tested on benchmark circuits. The results demonstrate that the proposed bounds have only a small error.
A method for real-time compensation of magnetometers embedded on smartphones (2016)

This paper deals with a real-time compensation method of long term time-variant disturbances for magnetometers embedded on smartphones. The proposed method compensates the effect of long term time-variant disturbances, continuously, using a least-square ellipsoid-based compensation procedure. In this paper, the proposed method is described and its advantages respect to the methods available in literature are highlighted. Furthermore, preliminary simulation tests have been performed and the obtained results reported.
Optimization of culture conditions for exopolysaccharides production in Rhizobium sp. using the response surface method (2006)

The combined effects of the processing parameters for exopolysaccharides production by Rhizobium sp. was studied using the experimental design and response surface methodology. The experiments were carried out using a fermenter with 20 L capacity, as the reactor. All processing parameters were online monitored. The temperature [(30 ± 1)oC] and pH value (7.0 ± 0.1) were kept constant throughout the experimental time. As statistical tools, a complete 2 3 factorial planning with central point and response surface were used to study the interactions among three relevant variables of the fermentation process: calcium carbonate concentration, aeration and agitation. The processing parameters setup for reaching a maximum response for exopolysaccharides production was obtained when applying the highest values for calcium carbonate concentration (1.1 g/L), aeration (1.3 vvm) and agitation (800 rpm). In addition, the combination of these optimum processing parameters yielded Y P/S (g/g) = 0.35.
Bulk scale fabrication of sodium tungsten bronze nanoparticles for applications in plasmonics (2018)

In order to advance plasmon-based technologies, new materials with low damping losses and high chemical stability are needed. In this letter, we report the bulk scale fabrication of sodium tungsten bronze (Na <sub>x</sub> WO<sub>3</sub>) nanoparticles with high Na content (x ≤ 0.83) using a furnace-assisted method. Phase purity and morphology is confirmed with x-ray diffraction and scanning electron microscopy. Plasmon responses are characterized using spectrophotometry and spatially-resolved electron energy-loss spectroscopy (EELS) in a scanning transmission electron microscope. Experimental EELS maps of individual nanoparticles show the excitation of distinct plasmon resonances at visible and near-infrared (NIR) frequencies, and these observations are supported by boundary element method simulations. Na <sub>x</sub> WO<sub>3</sub> is a promising alternative material for plasmonics due to its strong plasmon resonances when compared to Au, its simple nanofabrication, and low cost. In particular, their high NIR extinction makes these materials ideal for applications in solar control window coatings or plasmonic photocatalysis.
Surface Reconstruction From Non‐parallel Curve Networks (2008)

Building surfaces from cross-section curves has wide applications including bio-medical modeling. Previous work in this area has mostly focused on connecting simple closed curves on parallel cross-sections. Here we consider the more general problem where input data may lie on non-parallel cross-sections and consist of curve networks that represent the segmentation of the underlying object by different material or tissue types (e.g., skin, muscle, bone, etc.) on each cross-section. The desired output is a surface network that models both the exterior surface and the internal partitioning of the object. We introduce an algorithm that is capable of handling curve networks of arbitrary shape and topology on cross-section planes with arbitrary orientations. Our algorithm is simple to implement and is guaranteed to produce a closed surface network that interpolates the curve network on each cross-section. Our method is demonstrated on both synthetic and bio-medical examples.
On the flow between two rotating coaxial disks (1953)

Abstract The steady motion of a viscous fluid confined between two coaxial rotating disks is discussed both experimentally and theoretically. It is found experimentally that when the disks rotate in the same sense the main body of the fluid rotates as well, but if they rotate in opposite senses the main body of the fluid is almost at rest. An adequate theory is found to explain this.
New Synthesis of Fluorinated Pyrazoles (2010)

A new synthesis of fluorinated pyrazoles, a class of compounds with potential in medicinal chemistry, is described. The treatment of benzoylfluoroacetonitrile with hydrazine yielded the expected new 3-amino-4-fluoropyrazole, while the analogous reaction of α-cyano-α,α-difluoroketones with hydrazine in refluxing isopropanol surprisingly gave rise to 3-unsubstituted 4-fluoropyrazoles via an unprecedented mechanism. The isolation of intermediate hydrazine adducts led to a mechanistic rationale for this transformation.
Reviews (1988)

Landscape Planning by Tom Turner Hutchinson 1987 203 pp. £27.50p The Greening of the Cities by David Nicholson‐Lord Routledge and Kegan Paul 1987 270pp £6.95 Development Control: A Manual ‐Unit 3: Aesthetic Issues Oxford Polytechnic: RTPI Oxford Polytechnic, 1987
Antisense Oligonucleotides Targeting Influenza A Segment 8 Genomic RNA Inhibit Viral Replication (2016)

Influenza A virus (IAV) affects 5%-10% of the world's population every year. Through genome changes, many IAV strains develop resistance to currently available anti-influenza therapeutics. Therefore, there is an urgent need to find new targets for therapeutics against this important human respiratory pathogen. In this study, 2'-O-methyl and locked nucleic acid antisense oligonucleotides (ASOs) were designed to target internal regions of influenza A/California/04/2009 (H1N1) genomic viral RNA segment 8 (vRNA8) based on a base-pairing model of vRNA8. Ten of 14 tested ASOs showed inhibition of viral replication in Madin-Darby canine kidney cells. The best five ASOs were 11-15 nucleotides long and showed inhibition ranging from 5- to 25-fold. In a cell viability assay they showed no cytotoxicity. The same five ASOs also showed no inhibition of influenza B/Brisbane/60/2008 (Victoria lineage), indicating that they are sequence specific for IAV. Moreover, combinations of ASOs slightly improved anti-influenza activity. These studies establish the accessibility of IAV vRNA for ASOs in regions other than the panhandle formed between the 5' and 3' ends. Thus, these regions can provide targets for the development of novel IAV antiviral approaches.
Withdrawal of Cerivastatin Induces Monocyte Chemoattractant Protein 1 and Tissue Factor Expression in Cultured Vascular Smooth Muscle Cells (2003)

These observations suggest that statin withdrawal results in the activation of Rac and enhanced oxidative stress. The subsequent activation of redox-activated signal-transduction cascades results in the expression of MCP-1 and TF.
Computer-aided simulation for oxygen precipitation in silicon (1991)

This paper describes a computer simulation for oxygen precipitation in silicon crystals subjected to thermal treatments. In the simulation based on the classical nucleation theory, it is assumed that an oxygen precipitate is spherical and its nucleus is a carbon atom. In addition, to explain oxygen precipitation at high temperatures, the simulation takes into consideration coarsening of the precipitate, which is inferred from obtained three-step annealing results. Simulated results are compared with experimental results obtained from a complementary metal-oxide-silicon transistor thermal process in addition to the three-step annealings results. As a result, it is proven that the proposed simulation can predict the precipitated oxygen concentration in wafers subjected to various thermal treatments.
Raman Spectroscopy Follows Time-Dependent Changes in T Lymphocytes Isolated from Spleen of Endotoxemic Mice (2019)

T lymphocytes (T cells) are highly specialized members of the adaptive immune system and hold the key to the understanding the hosts' response toward invading pathogen or pathogen-associated molecular patterns such as LPS. In this study, noninvasive Raman spectroscopy is presented as a label-free method to follow LPS-induced changes in splenic T cells during acute and postacute inflammatory phases (1, 4, 10, and 30 d) with a special focus on CD4<sup>+</sup> and CD8<sup>+</sup> T cells of endotoxemic C57BL/6 mice. Raman spectral analysis reveals highest chemical differences between CD4<sup>+</sup> and CD8<sup>+</sup> T cells originating from the control and LPS-treated mice during acute inflammation, and the differences are visible up to 10 d after the LPS insult. In the postacute phase, CD4<sup>+</sup> and CD8<sup>+</sup> T cells from treated and untreated mice could not be differentiated anymore, suggesting that T cells largely regained their original status. In sum, the biological information obtained from Raman spectra agrees with immunological readouts demonstrating that Raman spectroscopy is a well-suited, label-free method for following splenic T cell activation in systemic inflammation from acute to postacute phases. The method can also be applied to directly study tissue sections as is demonstrated for spleen tissue one day after LPS insult.
Enhanced Antitumor Efficacy in Mice by Combination Treatment with Interleukin-1α and Interferon-α (1994)

The antitumor efficacy of recombinant murine interleukin-1 alpha (rMuIL-1 alpha) was evaluated either alone or in combination with recombinant human hybrid interferon alpha A/D (IFN-alpha A/D) against the murine B16 F10 malignant melanoma. Treatment of subcutaneous tumor-bearing mice intraperitoneally with rMuIL-1 alpha resulted in a dose-dependent inhibition of tumor growth with the greatest activity obtained with the maximum tolerated dose of rMuIL-1 alpha (10 micrograms per treatment). Augmented tumor inhibition comparable to that seen in mice treated with a high dose of rMuIL-1 alpha was observed in subcutaneous tumor-bearing mice injected with the combination of IFN-alpha A/D and a low dose of rMuIL-1 alpha. Similar inhibition of subcutaneous tumor growth was obtained in T-cell-deficient nude or natural killer cell-deficient beige mice. In contrast, treatment of mice bearing B16F10 experimental pulmonary metastases with rMuIL-1 alpha resulted in no decrease in the number of metastases, and rMuIL-1 alpha did not potentiate the antimetastatic activity of IFN-alpha A/D. A synergistic induction of IL-6 was induced in mice treated with the combination of rMuIL-1 alpha plus IFN-alpha A/D but the level of IL-6 induced was not correlated with inhibition of tumor growth because this elevation of IL-6 was not observed in tumor-bearing nude mice. No direct antiproliferative activity was demonstrable in vitro against B16 F10 cells with rMuIL-1 alpha, IL-6, or rMuIL-1 alpha plus IL-6, and addition of these cytokines did not enhance the antiproliferative activity of IFN-alpha A/D.(ABSTRACT TRUNCATED AT 250 WORDS)
Visualization of Mitochondrial Protein Import in Cultured Mammalian Cells with Green Fluorescent Protein and Effects of Overexpression of the Human Import Receptor Tom20 (1997)

The presequence of the ornithine transcarbamylase precursor (pOTC) was fused to green fluorescent protein (GFP), yielding pOTC-GFP and pOTCN-GFP containing the presequence plus 4 and 58 residues of mature ornithine transcarbamylase, respectively. When GFP cDNA was transfected into COS-7 cells, the cytosol and nucleus were fluorescent. On the other hand, pOTC-GFP cDNA gave strong fluorescence of a unique mitochondrial pattern. After fractionation of cells expressing pOTC-GFP with digitonin, fluorescence was recovered mostly in the particulate fraction. Immunoblot analysis showed that processed GFP was present in the particulate fraction, whereas pOTC-GFP was recovered in both the soluble and particulate fractions. pOTC-GFP and pOTCN-GFP synthesized in vitro were imported efficiently into the isolated mitochondria. Single and triple amino acid mutations in the presequence resulted in impaired mitochondrial import and in a loss of mitochondrial fluorescence. Perinuclear aggregation of fluorescent mitochondria was observed when the human mitochondrial import receptor Tom20 (hTom20) was coexpressed with pOTC-GFP. Overexpression of hTom20 (not DeltahTom20, which lacks the anchor sequence) resulted in stimulated mitochondrial import of pOTC-GFP in COS-7 cells. When pOTC-GFP cDNA was microinjected into nuclei of human fibroblast cells, mitochondrial fluorescence was detected as early as 2-3 h after injection. These results show that GFP fusion protein can be used to visualize mitochondrial structures and to monitor mitochondrial protein import in a single cell in real time.
Microthermoforming as a novel technique for manufacturing scaffolds in tissue engineering (CellChips®) (2004)

The CellChip is a microstructured polymer scaffold, which favours a three-dimensional cultivation of cells within an array of cubic microcontainers. The manufacturing process used so far is microinjection moulding combined with laser-based perforation. In a first attempt to simplify the process, costly perforation was avoided by using commercially available, inexpensive microfiltration membranes for the bottom of the microcavities. Microthermoforming is a promising novel technique which allows the CellChip to be produced from thin film. Working pressures of approximately 4000 kPa were required for the adequate moulding of 50 microm thick films from three different polymers (polystyrene, polycarbonate, cyclo-olefin polymer). Integrating drafts and chamfers in micromoulds is not going to eliminate an uneven thickness profile, but reduces demoulding forces. Microthermoformed CellChips of polycarbonate were perforated by an ion track technique to guarantee a sufficient supply of medium and gases to the cells. The prestructured CellChips were irradiated with 1460 MeV xenon ions at a fluence of a few 10(6) ions/cm2. The tracks were etched in an aqueous solution of 5 N NaOH at 30 degrees C, which resulted in cylindrical pores approximately 2 microm in diameter. Microinjection-moulded, membrane-bonded and thermoformed CellChips were subjected to comparative examination for viability in a cell culture experiment with parenchymal liver cells (HepG2). The cells stayed viable over a period of more than 20 days. No significant differences in viability between injection-moulded, membrane-bonded, and thermoformed CellChips were observed.
Preliminary Data Using Computed Tomography Texture Analysis for the Classification of Hypervascular Liver Lesions (2015)

Computed tomography texture analysis may prove valuable in lesion characterization. Differentiation between common hypervascular lesion types could be aided by the judicious incorporation of texture parameters into clinical analysis.
Design of keystream generator (1998)

A new design of nonlinear combination generator is proposed. The nonlinear combining function employed is changed dynamically by permuting the variables in the nonlinear function. Simulated results show that the linear complexity of the resulting keystream is lower bounded by half the period of the keystream.
Phosphoinositides: Chemistry, Biochemistry, and Biomedical Applications (1999)

This volume summarizes current research on cellular signal transduction involving inositol phosphates and phospholipids, and features contributions from some of the leading laboratories. The chapters span three key topics: the metabolism of inositol phosphates and identification of proteins that interact with polyphosphorylated phosphatidylinositols; the mechanisms and structure of phosphatidylinositol-specific phospholipase C; and the synthesis and biological properties of analogs for phosphoinositides.
Development of Automatic Image Processing System for Grinding Wheel Surface. (Continued report). Mapping of Cutting Edges and Its Application to the Analysis of Turing Process. (2002)

This report deals with the useful software program built for the previously developed automatic image processing system so that the characteristics of the wheel surface consisted of a great number of cutting edges beyond one thousand can be grasped more easily. The program is mainly realized by three kinds of utilities; a) the wheel surface viewer can display about 30 micro-scope images on CRT display at the same time in order to judge the condition of wear land of cutting edges at a glance, b) the cutting edge list can be used to estimate the change of cutting edges in the processes of truing, dressing and grinding, c) the cutting edge map can show visibly the position and the distribution of all the cutting edges on the whole wheel surface and clarify the difference of cutting edges before and after the processes. The new utilities are ascertained available in the experiment for following the behaviors of cutting edges in actually truing process.
A single chip video front end decoder (1993)

All of the processing necessary to convert an analog video signal into a digital component stream has been integrated onto a single 44 pin IC. The wide variety of supported formats, the range of processing options, and the use of consumer packages uniquely qualify this chip for use in the evolving multimedia market. The notable features of the video pixel decoder include single power supply (5 V); power up default state; internal 8-b ADCs (analog-to-digital converters) with clamping and AGC (automatic gain control); multistandard color decoding NTSC (National Television System Committee)/PAL/SECAM/S-VHS; 8-bit, 4:2:2 processing; integrated delay line; horizontal resizing between 32 and 1056 pixel/line; alpha key generation; YUV (yellow, ultraviolet) 4:2:2 or YUV 4:1:1 or YUV 4:4:4 or gamma -corrected RGB (red, green, blue) 4:4:4 (15, 16 or 24 b); synchronous output mode with sync signals; and asynchronous mode via FIFO (first in, first out) with status flags.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>