gebhart/patrepeval huggingface dataset:
Flocking for Heterogeneous Robot Swarms: A Military Convoy Scenario (2007)

In this paper we apply a popular flocking control algorithm to a heterogeneous swarm of robots. The flocking controller contains separation, cohesion and velocity matching terms and has been shown to converge properly in the case of homogeneous swarms. The swarm models a military convoy unit with supply vehicles, defenders, and attackers. Each class of vehicle possesses different maneuvering capabilities and different objectives. In each case we modify the controller accordingly and analyze the emergent behavior of the swarm.
Birefringence effect of optical fiber laser with intracore fiber Bragg grating (1992)

The spectra of Nd/sup 3+/- and Pr/sup 3+/-doped fibre lasers utilizing an intracore Bragg grating reflector written at 1.08- mu m Bragg wavelength and a dichroic mirror for cavity feedback have been investigated under 0.6-GHz resolution. Two oscillating frequencies corresponding to two orthogonal linear polarization states of laser emission were observed. The frequencies and orientations of the two linearly polarized emissions could be changed by varying the fiber birefringence with an inline polarization controller. A phenomenological model is proposed to explain the experimental results.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Cigarette Smoking and Major Depression (1998)

The authors review recent literature that has demonstrated an association between cigarette smoking behavior and major depression. Persons with major depression are more likely to smoke and to have difficulty when they try to stop. When they manage to succeed in stopping, such persons are at increased risk of experiencing mild to severe states of depression, including full blown major depression. The period of vulnerability to a new depressive episode appears to vary from a few weeks to several months after cessation. This knowledge suggests a relationship between smoking and depression that is complex, pernicious, and potentially life-long. It is recommended that cessation treatments incorporate screening procedures that will identify those patients with a propensity to depression and monitor the emergence of postcessation depression, particularly in those with a history of depression.
Analysis of bandpass filtering behaviour of singlemodedepressed-core-index photonic-bandgap fibre (2000)

The propagation of light into a depressed-core-index photonic bandgap fibre is strongly dependent on the wavelength. The transmission spectrum is experimentally measured and successfully compared with theoretical predictions.
Offloading Operability of Small Scale AG FLNG With Side-by-Side Moored Small Scale LNG Carrier in Offshore West Africa (2017)

This study describes one of the technical solutions for Small Scale FLNG (SSFLNG)[1] development specifically designed to monetize Associated Gas (AG) of producing oil fields located within convenient distance of an existing LNG Plant or Port with LNG storage facility. Limited production capacity combined with short range small scale LNG carriers (SSLNGC), provide a cost effective means for LNG production. Ship to ship off-loading operation by loading arm has been considered in AG SSFLNG. Produced LNG is to be off-loaded from the SSFLNG to side-by-side moored SSLNGC. Relative motion and dynamic load acting on loading arm system in side-by-side mooring arrangement is one of key factors to estimate the offloading operability of the AG SSFLNG. In this paper, a numerical two-body motion analysis for the side-by-side moored SSFLNG in frequency- and time-domain is carried out. Also, the basic engineering work is carried out for the marine loading arms (MLA). Since the MLA reacts approximately as a linear system, it is calculated by a full spectral RAO analysis for each of the worst load cases issued from the spectral ranking. All loads and stresses inside the MLA are verified in accordance with EN1474-1[2] for the situations identified in the previous step. A high level fatigue analysis focused on the cryogenic swivel joints is carried out. Based on the numerical calculation for relative motion in side-by-side moored FLNG, we have been performed structural assessment for MLA in several environment conditions. The structural integrity of both MLA and the LNGC manifold are validated during offloading for Offshore West Africa.
Application of Computed Tomography Processed by Picture Archiving and Communication Systems in the Diagnosis of Acute Achilles Tendon Rupture (2016)

The applications of CT examination in the diagnosis of the acute Achilles tendon rupture (AATR) were investigated. A total of 36 patients with suspected acute Achilles tendon rupture were tested using physical examination, ultrasound, and 3DCT scanning, respectively. Then, surgery was performed for the patients who showed positive result in at least two of the three tests for AATR. 3DVR, MPR, and the other CT scan image processing and diagnosis were conducted in PACS (picture archiving and communication system). PACS was also used to measure the length of distal broken ends of the Achilles tendon (AT) to tendon calcaneal insertion. Our study indicated that CT has the highest accuracy in diagnosis of acute Achilles tendon complete rupture. The length measurement is matched between PACS and those actually measured in operation. CT not only demonstrates more details directly in three dimensions especially with the rupture involved calcaneal insertion flap but also locates the rupture region for percutaneous suture by measuring the length of distal stump in PACS without the effect of the position of ankle. The accuracy of CT diagnosis for Achilles tendon partial rupture is yet to be studied.
Genome-Scale Metabolic Model of <i>Helicobacter pylori</i> 26695 (2002)

A genome-scale metabolic model of Helicobacter pylori 26695 was constructed from genome sequence annotation, biochemical, and physiological data. This represents an in silico model largely derived from genomic information for an organism for which there is substantially less biochemical information available relative to previously modeled organisms such as Escherichia coli. The reconstructed metabolic network contains 388 enzymatic and transport reactions and accounts for 291 open reading frames. Within the paradigm of constraint-based modeling, extreme-pathway analysis and flux balance analysis were used to explore the metabolic capabilities of the in silico model. General network properties were analyzed and compared to similar results previously generated for Haemophilus influenzae. A minimal medium required by the model to generate required biomass constituents was calculated, indicating the requirement of eight amino acids, six of which correspond to essential human amino acids. In addition a list of potential substrates capable of fulfilling the bulk carbon requirements of H. pylori were identified. A deletion study was performed wherein reactions and associated genes in central metabolism were deleted and their effects were simulated under a variety of substrate availability conditions, yielding a number of reactions that are deemed essential. Deletion results were compared to recently published in vitro essentiality determinations for 17 genes. The in silico model accurately predicted 10 of 17 deletion cases, with partial support for additional cases. Collectively, the results presented herein suggest an effective strategy of combining in silico modeling with experimental technologies to enhance biological discovery for less characterized organisms and their genomes.
Single-frame measurement of complex laser pulses tens of picoseconds long using pulse-front tilt in cross-correlation frequency-resolved optical gating (2013)

We demonstrate the use of pulse-front tilt (PFT) in cross-correlation frequency-resolved optical gating (XFROG) implemented in polarization-gate geometry to measure arbitrary complex ultrashort pulses tens of picoseconds long on a single-camera frame with the potential for a single-shot measurement. The PFT is generated by a diffraction grating. We measured chirped double pulses separated by 4.7 and 24 ps with fine details and accurately retrieved them using the standard XFROG retrieval algorithm. The temporal range of our device is 28 ps, an order of magnitude longer than available from standard single-shot FROG devices without PFT.
Conformational Stability of Mammalian Prion Protein Amyloid Fibrils Is Dictated by a Packing Polymorphism within the Core Region (2013)

Mammalian prion strains are believed to arise from the propagation of distinct conformations of the misfolded prion protein PrP(Sc). One key operational parameter used to define differences between strains has been conformational stability of PrP(Sc) as defined by resistance to thermal and/or chemical denaturation. However, the structural basis of these stability differences is unknown. To bridge this gap, we have generated two strains of recombinant human prion protein amyloid fibrils that show dramatic differences in conformational stability and have characterized them by a number of biophysical methods. Backbone amide hydrogen/deuterium exchange experiments revealed that, in sharp contrast to previously studied strains of infectious amyloid formed from the yeast prion protein Sup35, differences in β-sheet core size do not underlie differences in conformational stability between strains of mammalian prion protein amyloid. Instead, these stability differences appear to be dictated by distinct packing arrangements (i.e. steric zipper interfaces) within the amyloid core, as indicated by distinct x-ray fiber diffraction patterns and large strain-dependent differences in hydrogen/deuterium exchange kinetics for histidine side chains within the core region. Although this study was limited to synthetic prion protein amyloid fibrils, a similar structural basis for strain-dependent conformational stability may apply to brain-derived PrP(Sc), especially because large strain-specific differences in PrP(Sc) stability are often observed despite a similar size of the PrP(Sc) core region.
[Refractive error and amblyopia in children]. (1992)

The refractive status of 3,099 children was analyzed. The result showed that the incidence and degree of hyperopia decreased gradually and those of myopia increased along with the growing up of children in ametropia. In binocular refractive amblyopia, high and medium hyperopia and myopia in severe and medium amblyopia were significantly more than those in mild amblyopia. In monocular refractive amblyopia, high and medium hyperopia and high myopia in the amblyopic eyes were more than those in the nonamblyopic eyes. The refractive status of binocular esotropic amblyopia had no significant difference in various ages and degrees of amblyopia. There was also no significant difference between the refractive status of the amblyopic and nonamblyopic eyes in monocular esotropic amblyopia. It was considered that refractive amblyopia was closely related to high ametropia and the deviation of the eye might be the main cause of strabismic amblyopia.
An improved branch and bound algorithm for the maximum clique problem (2007)

A new algorithm for finding a maximum clique in an undirected graph is described. An approximate coloring algorithm has been improved and used to provide bounds to the size of the maximum clique in a basic algorithm which finds a maximum clique. This basic algorithm was then extended to include dynamically varying bounds. The resulting algorithm is significantly faster than the comparable algorithm.
Kinetic analysis of the interaction of alkyl glycosides with two human <i>β</i>-glucosidases (1989)

This paper addresses the similarities and differences in the topology of the catalytic centres of human liver cytosolic beta-glucosidase and placental lysosomal glucocerebrosidase, and utilizes well-documented reversible active-site-directed inhibitors. This comparative kinetic study was performed mainly to decipher the chemical and structural nature of the active site of the cytosolic beta-glucosidase, whose physiological function is unknown. Specifically, analysis of the effects of a family of alkyl beta-glucosides consistently displayed 100-250-fold lower inhibition constants with the cytosolic broad-specificity beta-glucosidase compared with the placental glucocerebrosidase; for example, with octyl beta-D-glucoside the Ki values were 10 microM and 1490 microM for the cytosolic and lysosomal beta-glucosidases respectively. Furthermore the higher affinity of the cytosolic beta-glucosidase than glucocerebrosidase for the amphipathic alkyl beta-D-glucosides was validated by the greater increase in the free energy of binding with increasing alkyl chain length [delta delta G0 (K,)/CH2: lysosomal enzyme, 2.01 kJ/mol (480 cal/mol); cytosolic enzyme, 3.05 kJ/mol (730 cal/mol)]. The implications of the presence of highly non-polar domains in the active site of the cytosolic beta-glucosidase are discussed with regard to its potential physiological substrates.
We are Big Data (2016)

Sander Klous holds a PhD in High Energy Physics and contributed to the discovery of the Higgs boson at CERN (Nobel prize 2013). Klous works at KPMG and is professor in Big Data at the University of Amsterdam. Nart Wielaard is a self-employed consultant and business writer. He develops compelling and clear stories on complex topics for a broad range of clients. Wielaard specializes in the domain where technology, society and business meet. .
Generating a high brightness multi-kilowatt laser by dense spectral combination of VBG stabilized single emitter laser diodes (2014)

Generating high power laser radiation with diode lasers is commonly realized by geometrical stacking of diode bars, which results in high output power but poor beam parameter product (BPP). The accessible brightness in this approach is limited by the fill factor, both in slow and fast axis. By using a geometry that accesses the BPP of the individual diodes, generating a multi kilowatt diode laser with a BPP comparable to fiber lasers is possible. We will demonstrate such a modular approach for generating multi kilowatt lasers by combining single emitter diode lasers. Single emitter diodes have advantages over bars, mainly a simplified cooling, better reliability and a higher brightness per emitter. Additionally, because single emitters can be arranged in many different geometries, they allow building laser modules where the brightness of the single emitters is preserved. In order to maintain the high brightness of the single emitter we developed a modular laser design which uses single emitters in a staircase arrangement, then coupling two of those bases with polarization combination which is our basic module. Those modules generate up to 160 W with a BPP better than 7.5 mm*mrad. For further power scaling wavelength stabilization is crucial. The wavelength is stabilized with only one Volume Bragg Grating (VBG) in front of a base providing the very same feedback to all of the laser diodes. This results in a bandwidth of < 0.5 nm and a wavelength stability of better than 250 MHz over one hour. Dense spectral combination with dichroic mirrors and narrow channel spacing allows us to combine multiple wavelength channels, resulting in a 2 kW laser module with a BPP better than 7.5 mm*mrad, which can easily coupled into a 100 μm fiber and 0.15 NA.
Real-Time Vision System Based on Correlation Processing. (1995)

This paper describes a high-performance robot vision system that performs real-time tracking of moving objects and real-time optical flow computation. The system is implemented as a transputer-based vision system augmented with a high-speed correlation processor. The vision unit is equipped with three image frame memories, each of which can be used simultaneously for image input, image processing, and image display. Thus, the system can devote all its computation power to image processing without waiting for image input or image display. The vision board is also equipped with a correlation processor. Using the chip, we have developed a very fast correlation based robot vision system. This system can also be used as multi-processor configuration to greatly increase performance.
RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by <i>fgf8</i> silencing (2005)

The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult to knock out individual gene expression. Recently, the possibility of silencing gene expression by RNAi in chick embryos has been reported. However, published studies show only discrete quantitative differences in the expression of the endogenous targeted genes and unclear morphological alterations. To elucidate whether the tools currently available are adequate to silence gene expression sufficiently to produce a clear and specific null-like mutant phenotype, we have performed several experiments with different molecules that trigger RNAi: dsRNA, siRNA, and shRNA produced from a plasmid coexpressing green fluorescent protein as an internal marker. Focussing on fgf8 expression in the developing isthmus, we show that no morphological defects are observed, and that fgf8 expression is neither silenced in embryos microinjected with dsRNA nor in embryos microinjected and electroporated with a pool of siRNAs. Moreover, fgf8 expression was not significantly silenced in most isthmic cells transformed with a plasmid producing engineered shRNAs to fgf8. We also show that siRNA molecules do not spread significantly from cell to cell as reported for invertebrates, suggesting the existence of molecular differences between different model systems that may explain the different responses to RNAi. Although our results are basically in agreement with previously reported studies, we suggest, in contrast to them, that with currently available tools and techniques the number of cells in which fgf8 gene expression is decreased, if any, is not sufficient to generate a detectable mutant phenotype, thus making RNAi useless as a routine method for functional gene analysis in chick embryos.
Diagnostic potential of mitochondrial DNA assessment in patients with optic neuropathy. (2000)

Assessment of mtDNA provides a useful diagnostic aid in the definition and exclusion of LHON, in particular family history-negative, otherwise undefined bilateral optic nerve inflammatory disease.
Design Style Case Study for Embedded Multi Media Compute Nodes (2005)

Users expect future handheld devices to provide extended multimedia functionality and have long battery life. This type of application imposes heavy constraints on both (realtime) performance and energy consumption and forces designers to optimise all parts of their platform. In this experiment we focus on the different processor core design options for embedded platforms, including the effect of instruction memory hierarchy on the energy consumption. The results show that significant improvements for energy efficiency and/or performance over currently used RISC or VLIW processors can be achieved. We conclude, based on concrete data for a realistic application, that different styles, including both configurable hardware and instruction set processors, find their way into heterogeneous platforms and designers need to be aware of the trade-offs. Secondly, we show for the same application task that a heavily optimised instruction/configuration memory hierarchy can significantly reduce the energy consumption of this part, so it forms a crucial part of every energy aware design.
Size and distortion invariant object recognition by hierarchical graph matching (1990)

A neural system is presented for invariant object recognition. Its flexibility is demonstrated with freely taken camera images of human faces. The system is an application of the dynamic link architecture, which owes its strength to an enhancement of tradition neural networks by a new kind of variable to express the hierarchical grouping of neurons. This capability is used to group primitive local feature detectors (Gabor-based wavelets) into composite feature detectors (jets) and to preserve neighborhood relationships between jets when they lose position information on the way from the image domain to the object domain. Due to the potential for grouping, objects can be represented as attributed graphs, with jets serving as attributes. Recognition is formulated as graph matching and is implemented as a topologically constrained diffusion of image-object links. A hierarchical sequence of matches, from low-frequency components of jets to high-frequency components, is used. Size invariance is achieved by interposing diffusion steps in magnification space. The system is implemented on a network of transputers
CORONAVIRUS and COVID-19 (2021)

Coronaviruses are a large family of viruses known to cause more serious diseases from the common cold, such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Coronaviruses were identified in the mid-1960s. Sars-Corona Virus (SARS-CoV) is a coronavirus that was first seen in China in February 2003 and causes severe acute respiratory failure. As the largest known RNA viruses (because coronaviruses have the largest genome of RNA viruses), CoVs are further divided into four types: alphacoronavirus (α-CoV), betacoronavirus (β-CoV), gammacoronavirus (γ-CoV), and deltacoronavirus (δ-CoV); the first two only infect mammals, including bats, pigs, cats and humans. Gammacoronavirus mostly infects birds and Deltacoronavirus can infect both birds and mammals. This novel coronavirus is now the seventh member of the Coronaviridoe, which is known to infect humans. All Coronaviruses belong to a genus. All of these genuses are in the Coronaviridae family, making up one of the two subfamilies. Coronavirus, Nidovirales, which causes infections mainly in the respiratory and gastrointestinal tract, belongs to the Orthocoronavirinae subfamily, respectively in the Coronaviridae family. Previously, with serological analysis, the differences in the Coronavirus species used were understood and the Coronaviridae family was examined by dividing it into 4 antigenic groups. But then, by examining the monoclonol antibody analysis and nucleotide sequences in the species and divisio groups, the classification was reduced to 3 antigenic groups. Viruses in the coronavirus family have only slight differences in their genomes, with only five nucleotide differences between the three of the viruses. Regardless of the structure of the protein chains, the same results in the same groups showed that this classification is more accurate. Coronaviruses responsible for %30 of upper respiratory tract diseases in humans are included in group 1 (HCoV-229E) and group 2 (HCoV-OC43). TGEV (Porcine transmissible gastroenteritis virus), FCV (Feline coronavirus), CCV (Canine coronavirus) in group 1 and all members of group 2 are genetically very close to each other. IBV, the only member of the 3rd group, is not different from other coronaviruses, but it shows variations within its species. Group 1 and group 2 coronaviruses include mammalian viruses.
Impaired neuropsychological functioning in Tourette's syndrome subjects with co-occurring obsessive-compulsive and attention deficit symptoms (1997)

This study examined neuropsychological performance by 92 children with Tourette's syndrome (TS) grouped by the presence or absence of obsessive-compulsive and/or attention deficit symptoms. The identified groups did not differ with respect to age, education, age at onset of TS symptoms, or medication use. After statistical control for complex motor symptoms, impaired performance on measures of achievement and executive functioning was correlated with obsessive and obsessive/attention symptoms, but not with attention symptoms alone. The presence of both obsessive and attention symptoms identified children with impairment across several tasks. Clinical and functional implications are discussed.