gebhart/patrepeval huggingface dataset:
Experiments on the degradation of cephalosporin C (1956)

Research Article| April 01 1956 Experiments on the degradation of cephalosporin C E. P. Abraham; E. P. Abraham 1Sir William Dunn School of Pathology, University of Oxford Search for other works by this author on: This Site PubMed Google Scholar G. G. F. Newton G. G. F. Newton * 1Sir William Dunn School of Pathology, University of Oxford Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1956) 62 (4): 658–665. https://doi.org/10.1042/bj0620658 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation E. P. Abraham, G. G. F. Newton; Experiments on the degradation of cephalosporin C. Biochem J 1 April 1956; 62 (4): 658–665. doi: https://doi.org/10.1042/bj0620658 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1956 CAMBRIDGE UNIVERSITY PRESS1956 Article PDF first page preview Close Modal You do not currently have access to this content.
A Further Study of Extremely Weak Acids (1936)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Further Study of Extremely Weak AcidsW. K. McEwenCite this: J. Am. Chem. Soc. 1936, 58, 7, 1124–1129Publication Date (Print):July 1, 1936Publication History Published online1 May 2002Published inissue 1 July 1936https://pubs.acs.org/doi/10.1021/ja01298a017https://doi.org/10.1021/ja01298a017research-articleACS PublicationsRequest reuse permissionsArticle Views491Altmetric-Citations167LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An intravenous injection of melatonin: formulation, stability, pharmacokinetics and pharmacodynamics (2012)

Two different intravenous (IV) formulations for melatonin at strength of 5 mg/ml; one using 2hydroxypropyl-B-cyclodextrin and propylene glycol to increase solubility and stability, and a second having additional antioxidant and chelating agent to reduce oxidation and hydrolysis were investigated. Both formulations were tested for clarity, pH stability, sterility, endotoxins, particulate matter according to US Pharmacopoeia Revision 31 (USP31), and photostability according to ICH guideline (ICH (Q1B), Option2), accelerated stability at 25 o C/75% RH for 6 mo, and real time stability for one year at 30 o C/75%RH, according to IHC guidelines. The pharmacokinetics of the IV dose were investigated in Wistar rats, and the antioxidant effect determined ORAC analysis of rat plasma. Both formulations passed USP tests for purity and stability, although the formulation without antioxidant exhibited more color and pH change over the testing period. Formulation 2 showed expected pharmacodynamics on injection in rat (20 µg/200 µl/rat), and plasma showed a significant increase (p<0.05) of ORAC antioxidant capacity from 10 min after injection. This study provides evidence of suitable intravenous formulations of melatonin for bioavailability or studies.
Correlation between leakage current density and threading dislocation density in SiGe <i>p-i-n</i> diodes grown on relaxed graded buffer layers (2001)

A correlation between bulk leakage current density and threading dislocation density in silicon–germanium mesa-isolated diodes fabricated on relaxed graded buffer layers is presented. Si0.75Ge0.25 p-i-n diodes were grown on SiGe graded buffers with different grading rates. Graded buffers with different grading rates yielded “virtual substrates” with varying densities of threading dislocations. Bulk leakage current densities were differentiated from surface leakage currents by using p-i-n diodes with different areas. We demonstrate that the increase in bulk leakage current density in SiGe p-i-n diodes can be modeled by generation processes assisted by deep levels related to threading dislocations.
Phenotypic switching of Thiobacillus ferrooxidans (1988)

Two solid medium formulations, designated 100:10 and 10:10, were developed for the growth of Thiobacillus ferrooxidans. The new media contain a mixture of both ferrous iron and thiosulfate as available energy sources, permitting the detection of colony morphology variants that arise spontaneously in a wild-type population. Several morphological and physiological characteristics of a class of T. ferrooxidans variants, termed LSC for large spreading colony, are described. LSC variants lack the ability to oxidize iron but retain the capacity to utilize thiosulfate or tetrathionate as energy sources. An LSC colony spreads on the surface of solid 100:10 medium as a monolayer of cells in a fashion resembling that of certain swarming or gliding bacteria. The LSC variant reverts to a parental wild type at frequencies that vary in different independently arising isolates. The identity of the LSC variant as a derivative of the parental wild-type T. ferrooxidans was established by Southern blot hybridization.
Synthesis, Structure, and Electrochemistry of Palladium Complexes with Camphor-Derived Chiral Ligands (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, Structure, and Electrochemistry of Palladium Complexes with Camphor-Derived Chiral LigandsM. Fernanda N. N. Carvalho, Luciana M. G. Costa, Armando J. L. Pombeiro, Annette Schier, Wolfgang Scherer, Siamak Khalili Harbi, Uwe Verfuerth, and Rudolf HerrmannCite this: Inorg. Chem. 1994, 33, 26, 6270–6277Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/ic00104a042https://doi.org/10.1021/ic00104a042research-articleACS PublicationsRequest reuse permissionsArticle Views305Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
<i>In situ</i>mechanical characterization of CoCrCuFeNi high-entropy alloy micro/nano-pillars for their size-dependent mechanical behavior (2016)

High entropy alloys (HEAs), as a new kind of alloys with equi- or near equi-atomic alloy compositions, have recently received increased interest, but their mechanical properties at micro- and nanoscales are less studied, which could hinder their structural/functional applications in the small scales. In this work, the mechanical responses of single crystalline FCC-structured CoCrCuFeNi HEA micro- and nano-pillars were systematically investigated by an in situ SEM nanoindenter. The yield strengths of the HEA micro-/nano-pillars under uniaxial compression appear to be size-dependent (with the m value of ∼0.46 in the Hall-Petch law relationship), but less sensitive when compared to typical metal/alloy micro- and nano-structures (e.g. with the m values of 0.6–0.9 for FCC metals). We also observed and analyzed the slip systems of the plastically deformed micro-/nano-pillars, and discussed their deformation mechanisms together with the Young's modulus by multiple loading/unloading compressions experiments. Our results could provide useful insights in the design and application of HEA for functional micro- and nano-devices.
Experimental Verification of the Hall Effect during Magnetic Reconnection in a Laboratory Plasma (2005)

In this Letter we report a clear and unambiguous observation of the out-of-plane quadrupole magnetic field suggested by numerical simulations in the reconnecting current sheet in the magnetic reconnection experiment. Measurements show that the Hall effect is large in the collision-less regime and becomes small as the collisionality increases, indicating that the Hall effect plays an important role in collision-less reconnection.
Dielectric characterization of water sorption in epoxy resin matrices (1993)

Abstract Water sorption in epoxy based materials was analyzed by dielectric spectroscopy using remote sensors. A method to determine diffusion coefficients from the changes in permittivity during water absorption is proposed and was verified experimentally by comparison with standard water gain measurements. Although the technique is limited by electrode polarization phenomena, it is sensitive to the presence of water molecules and is capable of detecting different levels of water concentration as a function of frequency. The utilization of remote sensors demonstrated the capability of dielectric analysis to be applied both in the laboratory environment, and on a larger scale, as a nondestructive technique for monitoring environmental changes in actual polymer matrix composite parts.
Channel interaction and speech processing strategies for cochlear implants (2000)

A limitation of multichannel cochlear implants is that electrical channel interactions can arise when multiple electrodes are stimulated simultaneously. Channel interaction can be reduced by decreasing current levels delivered to each electrode, through improved electrode positioning and design, or by using speech processing strategies that stimulate electrodes sequentially. The goal of the present study was to examine the relationship between channel interaction and speech recognition for several speech strategies varying in the number of electrodes stimulated simultaneously. Based on previous research, susceptibility to channel interaction is expected to vary as a function of electrode configuration. Thus patients with strong susceptibility to channel interaction will produce higher speech recognition scores for sequential as opposed to simultaneous speech strategies. Speech strategy performance was evaluated with acute listening trials where patients identified consonants and vowels with each of the following speech strategies, listed in order from sequential stimulation to fully simultaneous stimulation: Continuous Interleaved Sampler (CIS), Paired Pulsatile Sampler (PPS), Hybrid Analog Pulsatile (HAP), and Simultaneous Analog Stimulation (SAS). Preliminary results showed that a greater degree of channel interaction was associated with the highest speech recognition scores for CIS, midrange scores for HAP, and the lowest scores for SAS. [Work supported by NIH.]
Effectiveness of Repeated Radiofrequency Neurotomy for Lumbar Facet Pain (2004)

Repeated radiofrequency neurotomies are an effective long-term palliative management of lumbar facet pain. Each radiofrequency neurotomy had a mean duration of relief of 10.5 months and was successful more than 85% of the time.
Dynamic Reconfiguration for Adaptive Computing Systems (DRACS) (2002)

The Dynamic Reconfiguration for Adaptive Computing Systems (DRACS) effort has exploited the emerging technology associated with run-time reconfigurable devices to develop system capabilities for run-time reconfiguration (RTR) of AGS hardware both in response to software control and in a data-driven manner. Using the DARPA-sponsored GSRG dynamically reconfigurable device, DRAGS has demonstrated a host-driven design and reconfiguration as well as two data-driven designs, one Finite State Machine (FSM) driven and one additional host-driven demonstration. This report describes how these can be used to develop a "virtual co-processor" that supports multiple reconfigurable computing applications residing in a single piece of hardware. One demonstration focus selected involves a subset of a realistic system scenario for parameter measurement processing in electronic warfare that can be improved through the use of dynamic reconfiguration.
Diversity and repertoire of IgW and IgM VH families in the newborn nurse shark (2004)

As in ratfish, sandbar and horn sharks, most nurse shark IgM VH genes are from one family with multiple, heterogeneous loci. Their IgW VH genes have diversified, forming at least three families. The neonatal shark Ig VH CDR3 repertoire, diversified via N-region addition, is shorter than the adult VDJ junction, suggesting one means of postnatal repertoire diversification is expression of longer CDR3 junctions.
Fitting Mixture Models to Birth Weight Data: A Case Study (1991)

Birth weights by gestational age are compared in two birth cohorts from Northern Finland, the first from 1966 and the second from 1985-1986. A curious fact in the data is that mean birth weight before the 39th week was lower in the latter series although the mean birth weight for the total series was higher. Similar findings have been reported in other series. A mixture model with the nonparametric regression function is proposed for studying the hypothesis that the difference was caused by more frequent gross errors in gestational assessment in the earlier cohort. The probability of an error in gestational assessment then greatly depends on the observed gestational age, which makes the mixture model nonstandard. Maximum likelihood solutions to the parameters in the proposed model were computed employing the general expectation-maximization (EM) algorithm. A technique for studying the effect of errors on the intrauterine weight gain curve is proposed and applied to our two birth cohorts. The risk of underestimation of gestational age seems to be larger in the previous series and the differences between the growth curves almost totally vanish when "corrected" by means of the mixture model.
GaAs/AlGaAs buried-heterostructure laser diodes with semi-insulating GaInP:Fe regrowth (2002)

GaAs/AlGaAs buried-heterostructure in-plane lasers and vertical-cavity surface-emitting lasers using GaInP:Fe as the burying layer have been fabricated and investigated. Regrowth of GaInP:Fe around etched laser mesas was achieved by hydride vapor phase epitaxy. The lasers exhibit good performance under CW operation and show promising high-speed characteristics.
Otolin-1 in Biological Fluids: A Possible Biomarker for Inner Ear Disease (2018)

The expression of Otolin-1 mRNA is highly restricted to the inner ear. A previous study showed that Otolin-1 is present in a significantly higher level in serum samples of patients with benign paroxysmal positional vertigo compared to healthy patients. Menière's disease (M.d.) leads to changes in the inner ear volumes and pressure. We therefore hypothesize that significantly increased levels of the protein Otolin-1 can be detected in blood, urine or saliva of patients suffering from M.d.
Time reversal of continuous-wave, steady-state signals in elastic media (2009)

Experimental observations of spatial focusing of continuous-wave, steady-state elastic waves in a reverberant elastic cavity using time reversal are reported here. Spatially localized focusing is achieved when multiple channels are employed, while a single channel does not yield such focusing. The amplitude of the energy at the focal location increases as the square of the number of channels used, while the amplitude elsewhere in the medium increases proportionally with the number of channels used. The observation is important in the context of imaging in solid laboratory samples as well as problems involving continuous-wave signals in Earth.
Ethanol Lock Technique: Review of the Literature (2009)

Central venous catheters (CVCs) are commonly used among adult and pediatric patients for administration of fluids, medications, and nutrition. Central line-associated (CLA) bloodstream infection (BSI) is a serious complication following CVC insertion. The aim of this review is to summarize available data regarding the ethanol lock technique, which is a proposed method for sterilizing the lumen of the catheter by instilling an ethanol solution and allowing it to dwell in the catheter for a certain amount of time. Studies on ethanol lock technique differ in ethanol concentrations, luminal dwell times, catheter types, inclusion of anticoagulants, use of systemic antibiotics, and use of the technique for prevention or for treatment of CLA BSI. In vitro studies demonstrate the efficacy of ethanol in the eradication of various pathogens. Definitive catheter integrity data are limited. Clinical trials report tolerable adverse events with ethanol locks, as well as encouraging results for prevention and treatment of CLA BSI.
IEGT design concept against operation instability and its impact to application (2002)

IEGT's (Injection Enhanced Gate transistors) and HV-IGBT's are inherently unstable inducing harmful current crowding and oscillation among paralleled chips or packages. The instability problem has become crucial in device design and application. This paper will describe the mechanism of the instability and propose effective solutions for device and package design against the problem.
Towards Audit 2.0 - A Web 2.0 Community Platform for Auditors (2010)

Generalized Audit Software (GAS) is a certain type of data analysis software that is increasingly used by auditors to improve the effectiveness and efficiency of audits. To date, the development and distribution of GAS follows traditional ways, that is the software is developed by a single company, without the direct participation of the users, and the completed product is sold as closed-source with no rights for any modifications. We argue that this traditional model hinders the further adoption of GAS due to the artificial barriers imposed on the users (e.g. vendor lock-in, lack of flexibility). Thus, this paper proposes a new form of GAS that is built upon the principles of Web 2.0 and aims at offering auditors a more open, more flexible, and less costly alternative to traditional solutions. The main artifacts of this new form of GAS are conceptualized in the paper and possible business models are outlined.
New visco-elastic mechanism design for flexible joint manipulator (2008)

We describe a space-efficient visco-elastic mechanism design for a small lightweight flexible joint of a human-symbiotic robot arm. Human-symbiotic robots that can provide daily life support will be required in houses, offices, facilities, and other places. Since they will often make physical contact with humans, their arms should have mechanical flexible joints to absorb the contact force and follow the human’s motion. Our design has two coaxial rotary elements: a torsion bar made from GUMMETAL and a rotary disk damper with the output hole at its center. These two elements are combined in parallel and coaxially, making our design highly space-efficient. This paper presents the specifications of the shear elastic characteristics of GUMMETAL measured in experiments using 1DOF (degree-of-freedom) test equipment. The results confirm that its shear elastic modulus is linear and has a small elastic hysteresis loop and our mechanism can provide the advantage for the robot servo control. Compared with the conventional design, our design can make a smaller lighter flexible joint.
Quantification of physiological aminoacids using aTRAQ® kit: evaluation and implementation of new markers (2015)

Nowadays, physiological amino acids profiling is based primarily on ion exchange chromatography (IEC) coupled to a post-column derivatization with ninhydrin and UV detection at two wavelengths. Unfortunately, this technique suffers various drawbacks such as long analysis time, high sample volume and specific costs related to the maintenance of a dedicated equipment. These reasons have led us to consider a technology switch to a mass spectrometry method. We tested the kit aTRAQ amino acids analysis for physiological samples (AB Sciex), offering a selective quantification of more than 40 amino acids, and have implemented the acquisition of various original markers to the initial method. The accuracy profiles established for each amino acid show that the results are very reliable. The linearity is assured between 1 and 1.000 μmol/L for most analytes. Result comparison with IEC method showed good agreement. Reference ranges are similar to those defined for the IEC method and patients with inborn errors of metabolism were readily identified. The aTRAQ method offers a valid alternative to IEC method with several advantages: reduced sample volume, decreased run time and increased specificity. However, the procedure requires a thorough review of all chromatographic peaks, process that considerably lengthens the overall time of the procedure. Finally, financial and practical considerations of both techniques have to be counterbalanced before initiating any methodological transition.
Texas Ranger, September 1947 (2016)

Table of Contents: Geology a la Staford (p. 2) -- Meet the Staff (p. 6) -- Ranging (p. 11) -- Perigrinus - Story of Law School (p. 13) -- The Fiendish Mr. Pong (p. 16) -- The Wheel (p. 17) -- Drink When I'm Dry (p. 22) -- Why I Want to Attend the University (p. 20) -- Texas Dresses Up (p. 22) -- The Cherry T Formation (p. 24) -- Compulsory Blanket Tax (p. 25) -- What's Wrong with the Students (p. 26) -- What's Wrong with the Professors (p. 27) -- Fun in you Spare Time (p. 28) -- Student Government (p. 30) -- Masterpiece or Monstrosity? (p. 31) -- The Best Circles (p. 32) -- Girl of the Month (p. 33) -- Fashion Writes Her Own Laws (p. 34) -- The Culver Sisters (p. 37) -- Record Reverie (p. 44) -- The Dream (p. 58) -- Method in this Madness (p. 60) -- Editorial Page (p. 64)