gebhart/patrepeval huggingface dataset:
Research on Web QoS Control Strategy Based on User Behaviour (2008)

This paper proposes a new Web QoS control strategy based on user behavior. Web QoS control strategy mainly include request classification, admission control, content adaptation technologies. The approach we take to Web QoS control first analyzes user access factors in request classification, admission control, and content self-adaptive strategies of Web QoS control mechanism, and then proposes user classification and content classification based on behavior analysis. In user classification, we take KNN algorithm to classify users' click-stream sequence, and experiment results show that our method can achieve satisfactory effect of classification.
A cloud based chat robot using dialogue histories for elderly people (2015)

The authors developed cloud based chat robot for exhilarating elderly people. Our robot is designed to keep users from being bored. Conventional chat robot systems use huge phrase database in advance. However, fixed phrase involves an immense amount of time and effort to make. The proposed system uses dialogue histories which are collected from users. This paper reports the effect of updating the phrase database by using histories.
Hot Isostatic Pressing of Castings (2008)

Abstract Hot isostatic pressing (HIP) is used to eliminate porosity in castings. This article provides the history and an overview of the HIP system. It illustrates the reasons for using HIP and discusses the criteria for selecting HIP process parameters. The main mechanisms by which pores are eliminated during HIP are reviewed. The article describes the effect of HIP on the mechanical properties, shape, and structure of castings as well as the effect of inclusions on as-HIPed properties. It examines the problems encountered in HIP and their solution. The article concludes with information on the economics of HIP system.
Physiologic and Therapeutic Aspects in Congenital Vein Valve Aplasia of the Lower Limb (1983)

Ten patients with congenital vein valve aplasia verified at contrast phlebography were evaluated clinically and by physiologic examinations. All had orthostatic edema and varicose veins, but leg ulcers and other "postphlebitic" sequelae were infrequent. Foot volumetry and measurement of ambulatory foot vein pressures revealed a severe deep venous incompetence with a defective muscle pump function and considerable reflux. Eight limbs were operated on with conventional varicose vein surgery and physiologically re-examined six to 26 weeks after the operation. All had an improved ambulatory pressure reduction (p less than 0.001). Foot volumetry revealed better muscle pump function (p less than 0.01), while the reflux flow was unchanged. Surgery of the incompetent superficial venous system is therefore recommended in cases with deep venous insufficiency due to congenital vein valve aplasia.
Hardware-in-the-loop simulation testing and its integration into a CACSD toolset (2002)

Hardware-in-the-loop simulation allows ECUs to be tested in a simulated environment in closed-loop. Engines, vehicles, and other components the ECU normally controls are replaced by high-fidelity models executed on a real-time computer system. It is shown that it is now possible to use the same tools for hardware-in-the-loop simulation that have been used in the control development, with the benefit of easy use and reuse of models.
Application of the squared mahalanobis distance for detecting outliers in multivariate non-Gaussian data (2018)

Application of the squared Mahalanobis distance and a quantile of the Chi-Square distribution for detecting outliers in multivariate non-Gaussian data on the basis of univariate and multivariate normalizing transformations is considered. The examples of outlier detection in the four-dimensional non-Gaussian data are given.
Quantum dots: Small 10/2010 (2010)

The cover picture shows a new method to illuminate quantum dots (QDs) by radiation luminescence as an internal light source. Taking advantage of the radioactive luminescent light at the visible and NIR range, many different fluorophores such as QDs can be exited to emit fluorescence for optical imaging. Three CdSe/ZnS core/shell QDs are chosen and irradiated by a β− emitter, 131I. The excited QDs can produce fluorescence for both in vitro and in vivo imaging. This study demonstrates an alternate strategy for the design of self-illuminating optical-imaging agents. Radiation-luminescence-excited fluorophores could also be readily adapted for dual-modality imaging. For more information, please read the Communication “Radiation-Luminescence-Excited Quantum Dots for in vivo Multiplexed Optical Imaging” by Z. Cheng et al., beginning on page 1087.
Homemade Site Directed Mutagenesis of Whole Plasmids (2009)

Site directed mutagenesis of whole plasmids is a simple way to create slightly different variations of an original plasmid. With this method the cloned target gene can be altered by substitution, deletion or insertion of a few bases directly into a plasmid. It works by simply amplifying the whole plasmid, in a non PCR-based thermocycling reaction. During the reaction mutagenic primers, carrying the desired mutation, are integrated into the newly synthesized plasmid. In this video tutorial we demonstrate an easy and cost effective way to introduce base substitutions into a plasmid. The protocol works with standard reagents and is independent from commercial kits, which often are very expensive. Applying this protocol can reduce the total cost of a reaction to an eighth of what it costs using some of the commercial kits. In this video we also comment on critical steps during the process and give detailed instructions on how to design the mutagenic primers.
Is the mitochondrial DNA involved in determining susceptibility to multiple sclerosis? (1998)

An increasing number of case reports on Leber's hereditary optic neuropathy (LHON) associated mitochondrial (mt)DNA point mutations in patients with multiple sclerosis (MS) raised the possibility that mitochondrial determinants may contribute to genetic susceptibility to MS. These observations prompted many laboratories including ours to perform comprehensive sequencing or large scale screening of the mtDNA in MS patients. Here we review the available data arguing for or against a mitochondrial hypothesis for MS. We conclude that pathogenic mtDNA point mutations are not associated with typical forms of this disease. A very small subgroup of MS patients, usually with prominent optic neuritis (PON), may carry pathogenic LHON mutations. This partial overlap between the two diseases may be related to the association of MS with a mtDNA haplotype (a set of mtDNA polymorphisms) within which pathogenic LHON mutations preferentially occur.
Solid phase synthesis of hydrophobic peptides on 1,6-hexanediol diacrylate cross-linked polystyrene resin (1999)

The synthesis of three hydrophobic peptides, which are partial sequences of thioredoxin, on a newly developed, flexible 1,6-hexanediol diacrylate cross-linked polystyrene, in good yield and purity, is described.
Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63. (1993)

Leishmania parasites cause a spectrum of diseases that afflict the populations of 86 countries in the world. The parasites can survive within the lysosomal compartments of the host's macrophages, unless those macrophages are appropriately activated. Despite the fact that protective immunity can be induced by vaccination with crude parasite preparations, little progress has been made toward a defined vaccine for humans. In this study the gene encoding the Leishmania surface proteinase gp63 was cloned and expressed as a cytoplasmic protein in a bacille Calmette-Guérin (BCG) vaccine strain. BALB/c and CBA/J mice were inoculated with a single dose of recombinant BCG and challenged with infective Leishmania major or Leishmania mexicana promastigotes. Significant protection was observed in both mouse strains against L. mexicana and in CBA/J against L. major, whereas only a delay in L. major growth was seen in BALB/c mice. Recombinant BCG also engendered a strong protective response against challenge with amastigotes of L. mexicana, demonstrating that the induced immune response recognized the intracellular form of the parasite. The results support the view that recombinant BCG expressing gp63 may prove a useful vaccine for inducing protective cell-mediated immune responses to Leishmania species causing American cutaneous leishmaniasis.
Higher Prevalence of Secretory CSE1L/CAS in Sera of Patients with Metastatic Cancer (2009)

Metastatic markers are highly useful diagnostic and prognostic indicators of cancer metastasis. Herein, we report that secretory CSE1L/CAS, a cellular apoptosis susceptibility protein, is a new marker for metastatic cancer. CAS was colocalized with matrix metalloproteinase-2 in vesicles surrounding the outside of MCF-7 cell membranes, and the COOH-terminal domain of CAS was associated with matrix metalloproteinase-2-containing vesicles. Immunohistochemical staining for CAS was positive in the stroma and gland lumens of human metastatic cancer tissues. CAS was also detected in conditioned medium from B16-F10 melanoma cells and more frequently in the sera of patients with metastatic cancer than in sera from patients with primary cancer. Specifically, the prevalence of serum CAS in serum samples from 146 patients was 58.2% (32 of 55), 32.0% (8 of 25), and 12.1% (8 of 66) for patients with metastatic, invasive, and primary cancers, respectively. Our results suggest that CAS is a secretory protein associated with cancer metastasis, which may have clinical utility in metastatic cancer screening and diagnosis.
A focusing X-ray camera for recording low-angle diffraction from small specimens (1983)

An X-ray camera is required in many low-angle diffraction experiments to focus the X-ray beam incident on the specimen. This paper describes an X-ray camera designed to record two-dimensional diffraction data from small specimens with unit cells as large as 50 nm. It matches the 200 μm focal spot of a rotating-anode X-ray generator to an electro-optical detector with a spatial resolution of 300 μm. The camera is very flexible and can accommodate a total source-to-detector distance of 2.5 m. The X-ray beam is focused by two 20 cm mirrors bent by simple two-point benders. The theory of such benders and the design of X-ray cameras incorporating them is discussed briefly. The paper also describes a fast (1 ms) X-ray shutter and simple ion chambers useful for alignment and operation.
Hypersensibilité aux virus, température et protéines solubles chez le Nicotiana xanthi n. c. Apparition de nouvelles macromolécules lors de la répression de la synthèse virale (1970)

National audience
United States Bridge Failures, 1951–1988 (1990)

Information drawn from national engineering magazines, a nationally distributed newspaper, and a statewide newspaper in Kentucky is presented for 114 bridge failures in the continental U.S. Failures during the construction stage and bridges that were closed in order to avoid failure were not considered. Of the 35 bridge failures reported in the Kentucky newspaper, only one was reported nationally. The study of this literature indicates that the principal source of bridge failures in the United States involves ships, trains, trucks, and cars colliding with the structures. In Kentucky, trucks exceeding the posted weight limit appear to be the major cause. Due to the scattered nature of the information, the formationn of a new division of the Federal Highway Administration or the National Transportation and Safety Board should be considered, whose mission would be to gather data and identify potential deficiencies in bridge design and construction.
Chronic administration of the luteinizing hormone-releasing hormone (LHRH) antagonist cetrorelix decreases gonadotrope responsiveness and pituitary LHRH receptor messenger ribonucleic acid levels in rats. (1996)

Continuous exposure to LHRH or its agonistic analogs results in a reduction of LHRH receptor sites and messenger RNA (mRNA) transcripts as well as in desensitization of the pituitary gonadotropes. To determine, whether LHRH antagonists might be similar in this respect to the agonists, we treated male rats for 4 weeks with daily sc injections of LHRH antagonist [Ac-D-Nal2,Phe(4Cl)2,D-Pal(3)3, D-Cit6,D-Ala10]LHRH (Cetrorelix acetate) or LHRH agonist, [D-Trp6]LHRH, in doses of 100 micrograms/animal-day. Another group of rats received a single im injection of 4.5 mg Cetrorelix pamoate depot, a sustained delivery formulation of the LHRH antagonist. An iv stimulation test with LHRH (200 ng/rat) was performed after 4 weeks of treatment. The rats were killed, and pituitary LHRH receptor characteristics were measured by RRA. To examine the effect of LHRH antagonist treatment on the expression of the pituitary LHRH receptor gene, some of the rats injected with Cetrorelix pamoate depot were killed after 2 weeks, and levels of LHRH receptor mRNA were determined by Northern blot and dot blot hybridization to a 32P-labeled rat complementary DNA probe. Our data show that LHRH-stimulated LH secretion at 30 min was suppressed by approximately 33% (P < 0.01) in rats pretreated with [D-Trp6]LHRH compared to that in animals injected with LHRH alone. Pretreatment of the rats with the LHRH antagonist suppressed the LH response to LHRH more markedly, the LH levels at 30 min were decreased by 89.8% and 96% in groups treated with Cetrorelix acetate and Cetrorelix pamoate depot, respectively. The testosterone response was virtually abolished in groups receiving Cetrorelix. The concentration of pituitary receptors for LHRH fell by 69% in the [D-Trp6]LHRH group, whereas the reductions in the Cetrorelix acetate group and in the group that received Cetrorelix pamoate depot were 77% and 82%, respectively. Treatment with Cetrorelix pamoate depot led to a 75-80% decrease in the levels of 5.0- and 4.5-kilobase forms of LHRH receptor mRNA compared to those in the control group. Dot blot analysis also showed 83% reduction in the mRNA for LHRH receptor. In conclusion, these data demonstrate that prolonged administration of LHRH antagonists such as Cetrorelix causes an impairment of gonadotropin secretion and a marked decrease in the levels of LHRH receptors as well as in the expression of the LHRH receptor gene. Thus, the down-regulation of pituitary LHRH receptors produced by LHRH antagonists appears to be similar to that resulting from the agonists.
From basic network principles to neural architecture: emergence of spatial-opponent cells. (1986)

The functional architecture of mammalian visual cortex has been elucidated in impressive detail by experimental work of the past 20-25 years. The origin of many of the salient features of this architecture, however, has remained unexplained. This paper is the first of three (the others will appear in subsequent issues of these Proceedings) that address the origin and organization of feature-analyzing (spatial-opponent and orientation-selective) cells in simple systems governed by biologically plausible development rules. I analyze the progressive maturation of a system composed of a few layers of cells, with connections that develop according to a simple set of rules (including Hebb-type modification). To understand the prenatal origin of orientation-selective cells in certain primates, I consider the case in which there is no external input, with the first layer exhibiting random spontaneous electrical activity. No orientation preference is specified to the system at any stage, and none of the basic developmental rules is specific to visual processing. Here I introduce the theory of "modular self-adaptive networks," of which this system is an example, and explicitly demonstrate the emergence of a layer of spatial-opponent cells. This sets the stage for the emergence, in succeeding layers, of an orientation-selective cell population.
Corrosion Testing Apparatus (1929)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCorrosion Testing ApparatusD. F. OthmerCite this: Ind. Eng. Chem. Anal. Ed. 1929, 1, 4, 209Publication Date (Print):October 1, 1929Publication History Published online1 May 2002Published inissue 1 October 1929https://pubs.acs.org/doi/10.1021/ac50068a015https://doi.org/10.1021/ac50068a015research-articleACS PublicationsRequest reuse permissionsArticle Views48Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Pedal error prediction by driver foot gesture analysis: A vision-based inquiry (2011)

Pedal errors have been reported as a cause of fatal traffic accidents. However it is not well understood why and when these pedal errors happen as well as how to mitigate them. In this paper, we study pedal error events in a real-world stop-and-go driving experiment, in which we quantitatively analyze foot behavior with measurements from embedded vehicle sensors (e.g. brake or acceleration pedal state) as well as a video input looking at the driver's foot. Our analysis shows some initial insights in factors influencing pedal errors (beside other possible causes like driver age, gender, and driver workload), including Sequential Effects and Cue Modality. We also develop a new vision-based approach for driver foot behavior analysis and use it to predict brake and acceleration pedal presses. Experimental results over twelve different subjects show that the proposed approach correctly detects pedal misapplications approximately 200ms before the actual press. This indicates the potential of applying this approach to predict and mitigate pedal errors in real-world driving.
Sonodynamically-induced anticancer effects by functionalized fullerenes. (2013)

These results suggest that PHF is a potential sonosensitizer for sonodynamic treatment of solid tumors.
Fluidic‐Directed Assembly of Aligned Oligopeptides with π‐Conjugated Cores (2013)

A microfluidic-based directed assembly strategy is employed to form highly aligned supramolecular structures. Formation of aligned synthetic oligopeptide nanostructures is accomplished using planar extensional flow, which induces alignment of underlying material suprastructures. Fluidic-directed assembly of supramolecular structures allows for unprecedented manipulation at the nano- and mesoscales, which has the potential to provide rapid and efficient control of functional material properties.
Influence of Halogen Plasma Atmosphere on SiO<sub>2</sub> Etching Characteristics (1991)

The influence of halogen plasma atmosphere on SiO 2 dry etching characteristics has been investigated using various halogen gases (SF 6 , Cl 2 , HBr and HI). It was found that in Cl 2 and HBr plasma atmospheres, when Si and SiO 2 are etched simultaneously, the SiO 2 etch rate increases to more than 4 times larger than the SiO 2 , etch rate obtained when only SiO 2 is etched. It was also found that the SiO 2 etch rate increases linearly in proportion to the total amount of silicon halide produced by etching Si. Low-order silicon halides such as SiX and SiX 2 (X=Cl or Br) connect with oxygen atoms in solid SiO 2 by Coulomb force since both silicon halide and SiO 2 are electrically polarized. Silicon oxyhalide ( e.g. , SiOX) as an etching product of SiO 2 is produced and desorbed by ion sputtermg or thermal evaporation. This is because that the Si-O bond strength in solid SiO 2 (108 kcal/mol) is weaker than that in a diatomic molecule (191 kcal/mol) composed of a Si atom from silicon halide and an O atom from SiO 2 . Consequently, SiO 2 etching progresses when silicon chloride or silicon bromide is contained in the plasma, which drastically decreases the etching selectivity of n + poly-Si to SiO 2 .
Peripheral monocytosis as a predictive factor for adverse outcome in the emergency department (2017)

Monocytosis is associated with chronic infections such as tuberculosis or endocarditis as well as rheumatic and myeloproliferative disorders. Monocytes are also involved in the pathogenesis of atherosclerosis, coronary artery disease, and stroke. The value of monocytosis as a prognostic marker in different diagnostic groups in the emergency setting, however, has not been investigated so far.The aim of the article is to study monocytosis as an outcome factor in the emergency setting.In a Swiss register study, we analyzed monocyte counts in 4238 patients aged >18 years who were admitted to the emergency department of a regional tertiary care hospital. Monocytosis was defined as 0.8×10 cells/L. Diagnoses were grouped into infection, cardiovascular, neurological, metabolic, gastrointestinal, pulmonary, or other. Thirty-day mortality was defined as the primary endpointA total of 1217 patients with monocytosis were identified. Patients with monocytosis at admission suffered more frequently from respiratory symptoms (17.7% vs 8.9%, P <.001) and infection as the final diagnosis (20.8% vs 10.3%, P <.001) while neurological diagnoses were significantly lower in the monocytosis group (15.3% vs 30.9%, P <.001). Patients with monocytosis suffered from more comorbidities such as congestive heart failure, chronic obstructive pulmonary disease, tumor, diabetes, or renal failure but not dementia. When adjusted for age, gender, comorbidities, and main diagnosis, the 30-day mortality (P = .002) and length of stay (P = .001) were significantly higher in patients with monocytosis. The 30-day mortality in patients with monocytosis was most notably influenced by a cardiological diagnosis (odds ratio 3.91).An increased monocyte count predicts adverse outcome in patients admitted to the emergency department. Mechanistic studies will be necessary to specify the potentially detrimental role of monocytosis in critical illness.
Comparison of In-Reactor Creep and Postirradiation Creep Tests of Structural Materials for Nuclear Applications (1969)

Neutron irradiation can cause the creep rate of a material to increase, decrease, or to remain unchanged. Each of these possible results has been observed in creep during neutron irradiation. In hep alloys increased creep rates have been observed both in Zircaloy-2 and Zr-2.5Nb at creep rates below 10-10 sec-1 at 300 C. At temperatures above 350 C in-reactor creep rates of Zr-2.5Nb are no different from those of unirradiated control tests, whereas in Zircaloy-2 the creep rate may increase, decrease, or remain the same on reactor shutdown, depending on the stress and temperature. Stress relaxation tests reported for zirconium alloys below 100 C resulted in more relaxation during neutron irradiation, suggesting faster creep rates. In-reactor creep tests for fcc alloys Type 304 stainless steel and Hastelloy X-280 at temperatures above 500 C have resulted in little if any difference in creep rate, although the range of second-stage creep was significantly reduced. Faster in-reactor creep rates are inferred for nickel, copper, and 18-8 stainless steel through greater stress relaxation during neutron irradiation below 100 C.