gebhart/patrepeval huggingface dataset:
FORMATION OF VOLATILE COMPOUNDS BY Pb<sup>212</sup> RECOILING FROM ALPHA DECAY<sup>1</sup> (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFORMATION OF VOLATILE COMPOUNDS BY Pb212 RECOILING FROM ALPHA DECAY1Jack Kay and F. S. RowlandCite this: J. Am. Chem. Soc. 1958, 80, 12, 3165Publication Date (Print):June 1, 1958Publication History Published online1 May 2002Published inissue 1 June 1958https://pubs.acs.org/doi/10.1021/ja01545a067https://doi.org/10.1021/ja01545a067research-articleACS PublicationsRequest reuse permissionsArticle Views19Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Targeted Screening for Elongation Factor Tu Binding Antibiotics. (1997)

The development of a screen targeted to antibiotics which bind elongation factor Tu (EF-Tu) is described. The method was based on selection of antimicrobial activities which were antagonized by exogenous EF-Tu. Kirromycin, a known inhibitor of EF-Tu, was positive in this screen. Among 47,000 microorganisms screened, several producers of kirromycin-type antibiotics were detected and the novel antibiotics GE2270 and GE37468 were discovered. These thiopeptide molecules constitute, along with amithiamycin, a novel class of antibiotics acting on EF-Tu.
A Randomized Controlled, Phase 2 Trial of the Viral Serpin Serp-1 in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention (2010)

URL: http://www.clinicaltrials.gov. Unique identifier: NCT00243308.
[Wilms' tumor in adults]. (1996)

4 rare cases are reported of adult Wilms' tumor in females aged 35-65. It had been developing subclinically for a long time and was detected at palpation or at abdominal ultrasonography. In the 35-year-old woman the weight of the removed tumor reached 3.5 kg. Wilms' tumor in the adults seems to run asymptomatically and, consequently, is likely to be diagnosed late.
A new magnetic field sensor based on magnetostrictive delay lines (1997)

A magnetic field sensor based on the dependence of the magnetostrictive delay line (MDL) response on its biasing magnetic field is presented in this paper. Such a sensor can be formed in an integrated array measuring the distribution of field along the MDL axis. Experimental results are reported for amorphous FeSiB wire MDL's, showing that high sensitivity and nonhysteresis are two advantages of this type of sensor.
BUILDING SOCIAL ENVIRONMENTS (6500–5500 BC) (2010)

Douglass Bailey's volume fills the huge gap that existed for a comprehensive synthesis, in English, of the archaeology of the Balkans between 6,500 and 2,000 BC; much research on the prehistory of Eastern Europe was inaccessible to a western audience before now, because of linguistic barriers. Bailey argues against traditional interpretations of the period, which focus on the origins of agriculture and animal breeding. He demonstrates that this was a period when monumental social and material changes occurred in the lives of the people in this region, with new technologies and ways of displaying identity. Balkan Prehistory will be required reading for everyone studying the Neolithic, Copper and early Bronze Ages of Eastern Europe.
Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An <sup>11</sup>C-(<i>R</i>)-PK11195 PET Study (2014)

Neuroinflammation is present in widespread brain areas in CFS/ME patients and was associated with the severity of neuropsychologic symptoms. Evaluation of neuroinflammation in CFS/ME patients may be essential for understanding the core pathophysiology and for developing objective diagnostic criteria and effective medical treatments.
DISULFIDE INTERCHANGE AND THE THREE-DIMENSIONAL STRUCTURE OF PROTEINS (1965)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Enhancement of film condensation rate on vertical tubes by longitudinal fins (1968)

Abstract Longitudinal rectangular fins loosely clamped to vertical tubes markedly increase the film condensation heat transfer coefficient. At a heat flux of 2×10 4 B.t.u./hr.sq.ft., twelve ⅛×0.013 fins clamped to a ½ in. O.D. vertical tube 42 ½ in. long (thus doubling the surface area of the tube) gave a condensation coefficient of 15,000 ± 15% B.t.u./hr.sq.ft. °F. compared with 1,620 B.t.u./hr.sq.ft. °F. for the same tube without fins, a ratio of h / h o of 9.2. The enhancement of the film condensation coefficient decreases as the heat flux increases and as the number of fins decreases. A model based on the effect of fin shape on film and rivulet hydrodynamics explains the observed behavior.
Integrity preservation and privacy protection for medical images with histogram-based reversible data hiding (2011)

For medical treatments, the integrity of the medical images, the authenticity of corresponding medical records, and the privacy of the patients are crucial requirements for the diagnosis of patient's disease. Therefore, how to retain the validity between images and medical records is an important topic for researches and real applications. In this paper, we apply the concept and implementation in digital rights management (DRM) systems, and propose a functional scheme for the above-mentioned goals. We employ the reversible data hiding scheme, a newly developed branch in DRM researches, for combating the goals. With the term of reversibility, it means that data, including patients' private information and the diagnosis data, can be hidden into the medical image by some means. Later on, the medical image containing data might be retrieved while necessary, and both the original image and the hidden data can be perfectly recovered. Data can be authenticated for enhanced privacy protection. Simulation results present the applicability of such an implementation.
Cellular interactions in hemopoiesis. (1987)

The role of immunocompetent cells in hemopoiesis remains controversial. We used an autologous system in which activated peripheral blood mononuclear cells (LAK) and interleukin-2 (IL-2) are administered to patients with cancer. We found little change in the numbers of circulating erythroid progenitors. Cocultures of these progenitors with LAK or supernatants lead to a decrease in the numbers of detectable burst forming units-erythroid (BFU-E) in culture. However, using an assay for burst promoting activity (BPA) we noted production of this hemopoietin by these LAK cells. We could not detect circulating levels of gamma interferon (IF). Variable levels were found in the LAK supernatants. We could not detect circulating eosinophil progenitors (CFU-Eo), but we did find evidence of production of a colony stimulating factor (CSF), which gave rise to a high number of eosinophil colonies in cultures of bone marrow. These results suggest that administration of LAK/IL-2 has potent effects on hemopoiesis and that these effects may emphasize the anemia and eosinophilia seen in patients receiving this therapy.
A nonlinear digital optimizing program for process control systems (1962)

This paper deals with nonlinear programming. In particular, it summarizes a newly developed program suitable for optimization of a computer-controlled process. The program applies probing and constraint-following algorithms which permit solving the optimization problem in difficult cases. These cases include nonlinear or discontinuous objective functions, constraint functions, and nonconvex domains.
Pharmacokinetics and Tolerance of the Natural Pentasaccharide (SR90107/ORG31540) with High Affinity to Antithrombin III in Man (1995)

This paper reports the results of the first administration of the synthetic natural pentasaccharide with high affinity to antithrombin III (NP) in man. This study was mainly focused upon the pharmacokinetic properties and general tolerance of the compound. Subcutaneous injections of doses < 1.43 mg (1000 anti Xa IU) did not generate measurable anti-Xa activities. After subcutaneous injection of increasing doses from 1.43 to 22.9 mg (1000 to 16,000 anti-Xa IU) to young healthy volunteers, it was found that the maximal concentration (Cmax) and the area under curve (AUC) were linearly correlated to the dose, that the total plasma clearances (CI) were constant and almost 3 times lower than those of the current low molecular weight heparins. Cmax were reached between 1 h and 3 h after the injection and the half-lives (t 1/2) were remarkably constant (13.1 h to 13.9 h). During the first 24 h following the injection, around 50% of the total administered dose was recovered in the urine in an active form, indicating that kidney plays a major roles in the elimination of NP. Consistent with these results, when NP was administered to healthy elderly volunteers having a lower creatinine clearance, the half-life of the compound was longer and the clearance lower. At doses exceeding 22.9, Cmax, and AUC were slightly lower than expected, the percentage of the dose recovered in the urine and the total apparent plasma clearance increased, suggesting that the excess of NP unbound to antithrombin III was excreted faster. NP was also administered at various dosages once or twice a day for 7 days to 20 elderly volunteers. Due to the long half-life of the compound the "steady state" was obtained 2 to 3 days after the first injection at which the mean Cmax was increased 1.5 to 2 times. The general tolerance of the compound was excellent. No relevant prolongations of the prothrombin time, of the activated partial thromboplastin time or of the bleeding time were observed. A re-bleeding phenomenon of the bleeding time incision, probably related to friability of the haemostatic plug, occurred in 3 subjects treated with the highest dose regimens: single injection of 26.6 mg (20,000 anti-Xa IU) (young volunteers) and repeated injections of 11.4 mg (8,000 anti-Xa IU) once a day for 7 days (elderly volunteers). At these times, plasma NP concentrations were between 2.9 and 3.6 micrograms.ml-1 (2 and 2.5 anti-Xa IU.ml-1).
Prevalence of Type 2 Diabetes (2012)

Type 2 diabetes mellitus, with an increasing prevalence in both developing and developed countries, has become one of the major health threats to the human being. According to the International Diabetes Federation (IDF), the number of patients with diabetes is 285 million in the year of 2010 and will rise to 438 million in 2030. The greater increase will occur in the developing countries than in developed world. Most recent data have shown that the prevalence of diabetes increased about 9 folds from 1980 (1.0%) to 2008 (9.7%) in China. This explosive increase in prevalence of diabetes is mostly attributed to the increase in risk profiles at a population level including population aging, obesity, physically inactive and unhealthy diet. Diabetes prevention programs that target lifestyle intervention are urgently needed.
Age effects of follicle-stimulating hormone and pulsatile luteinizing hormone secretion across the menstrual cycle of premenopausal women. (1996)

To characterize the differential aging response in gonadotropin secretion that occurs before menopause, we assessed pulsatile LH and serial FSH, estradiol (E2), and progesterone (P) concentrations in aging women across the menstrual cycle. We conducted 96 daytime studies during the follicular, midluteal, and late luteal phases of the same menstrual cycle in 32 volunteers, aged 40-50 yr (n = 16) and 19-39 yr (n = 16). Mean cycle length was shorter in the older women (26 +/- 0.4 vs. 27.6 +/- 0.6 days; P = 0.02), but mean plasma E2 and P values were similar in the two age groups. Mean plasma FSH was higher in the older group on all 3 study days. For LH, an age difference was observed during the late luteal phase, when mean plasma LH and pulse amplitude were higher in women over 40 yr of age (mean LH, 6.4 +/- 0.7 vs. 3.0 +/- 0.5 IU/L (P = 0.002); mean amplitude, 4.0 +/- 0.5 vs. 2.8 +/- 0.2 IU/L (P = 0.03)]. Pulse frequency was higher in the older group, but not different from that in younger women on all study days. When the subjects aged 35-39 yr were analyzed as a third age group (n = 8), age effects for mean LH persisted, and pulse frequency was higher in the group over 40 yr of age vs. women under age 35 yr (n = 8) in both the follicular phase (7.1 +/- 0.4 us. 5.6 +/- 0.8; P = 0.03) and late luteal phase (5.8 +/- 0.7 vs. 4.4 +/- 0.3; P = 0.03). Although highly variable, individual patterns of gonadotropin secretion in the women over age 40 yr included a sustained elevation in the FSH/LH ratio as well as a failure to demonstrate slow frequency, high amplitude LH pulses in the midluteal phase. In conclusion, 1) the age-related increase in FSH concentrations in ovulatory women, although more pronounced, is associated with phase-dependent enhancement of pulsatile LH secretion; 2) the higher LH concentrations are brought about by changes in both pulse frequency and amplitude; and 3) these age effects preempt overt reductions in cyclic E2 or P concentrations.
On mechanistic aspects of 5‐deazaflavin dependent dehydrogenation of alcohol (1987)

Abstract The reaction of 5‐deazaflavins with alcoholates was investigated and the direct hydride equivalent transfer from C 1 of alcoholates to C 5 of 5‐deazaflavins was confirmed by chemical methods. 5‐Alkoxy‐10‐butyl‐3‐methyl‐5‐deazaflavins were synthesized by treatment of 10‐butyl‐5‐chloro‐3‐methyl‐5‐deazaflavin with the corresponding alcoholates. The 5‐alkoxy‐5‐deazaflavins were reduced by sodium borodeuteride or sodium hydro‐sulfite in deuterium oxide or monodeuteriomethanol to give 10‐butyl‐3‐methyl‐1,5‐dihydro‐5‐deazaflavin‐5,5‐D 2 exclusively. 3,10‐Dimethyl‐5‐deazaflavin radical anion was detected by esr technique on treatment of 3,10‐dimethyl‐5‐deazaflavin with potassium in DMF. From the above reactions, a mechanism of 5‐deazaflavin dependent dehydrogenation of alcoholate was proposed.
[Prophylactic and therapeutic effects of beclomethasone inhalation on bronchial hyperresponsiveness and asthma: a randomized, double-blind, parallel-group controlled trial]. (1998)

The results suggested that BDP could significantly relieve the severity of BHR and symptoms in asthmatics, and could have some prophylactic effects on the development of asthma in those with asymptomatic BHR.
Prevalence of symptoms of dry mouth and their relationship to saliva production in community dwelling elderly: the SEE project. Salisbury Eye Evaluation. (1998)

Symptoms of dry mouth are common in the community dwelling elderly population, especially in white women, and correlate with decreased salivary production.
R-C Filter Circuits (1945)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation G. J. Thiessen; R‐C Filter Circuits. J. Acoust. Soc. Am. 1 April 1945; 16 (4): 275–279. https://doi.org/10.1121/1.1916291 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Technical Aspects and Recommended Treatment Algorithms in Triangular Osteosynthesis and Spinopelvic Fixation for Vertical Shear Transforaminal Sacral Fractures (2009)

Vertically unstable pelvic ring injuries associated with comminuted transforaminal sacral fractures present a special problem to the treating surgeon in applying stable fixation for maintaining reduction. Triangular osteosynthesis and spinal-pelvic constructs are relatively new techniques used to avoid loss of reduction for treating these difficult fractures, and the last decade has seen a marked increase in the use of these techniques. This article aims to describe the indications and technical aspects in the use of spinal-pelvic constructs for vertical shear sacral fractures such that they can be applied to better help the patients with these injuries.
Substrate Curvature Restricts Spreading and Induces Differentiation of Human Mesenchymal Stem Cells (2017)

While cells attach, spread, migrate, proliferate, and differentiate in three-dimensional (3D) micromechanical environments, the mechanical factors of these environments influence the shapes, sizes, and adhesion forces of the cells. Here, the authors culture human mesenchymal stem cells (hMSCs) on a unique class of curvature-defined substrates, micro glass ball embedded polyacrylamide gels, prepared with an improved protocol, and investigate the spreading responses of the hMSCs on the glass balls to study the effects of substrate curvature on the spreading of hMSCs. The authors find that, among the used diameters of glass balls, the minimum diameter of a glass ball on which an hMSC can attach and spread is 500 μm. In contrast to the well-spread morphologies with randomly-multiple lamellipodia for the hMSCs growing on the flat glass plates, the morphologies of the hMSCs growing on the glass balls are almost uniformly spindle-shaped with two lamellipodia. The sensitivities of the attachment and spreading morphology of an hMSC to substrate curvature are very different from those of a fibroblast. The RT-PCR analysis reveals that the substrate curvature alone can induce adipogenesis of the hMSCs. These findings imply that substrate curvature has profound effects on stem cell behaviors, and detailed and in-depth studies on these effects and their underlying biophysical mechanisms are necessary.
Threshold voltage extraction methods for MOS transistors (2002)

The threshold voltage of the MOS transistor is a very important parameter used in all circuit simulation programs. The aim of this paper is to compare several largely applied threshold voltage extraction methods used both for long channel and short channel MOSFETs. This methods use either the linear operation region or the saturation operation region of the transistors. The new derivative extraction method proposed in this paper doesn't depend on the operation region for long channel devices and gives comparable results for short channel devices. It is a very simple and accurate extraction method. The experimental data used in the paper were measured using a HP4155B system. The mathematical calculation and the threshold voltage extraction are performed using MATHCAD designed programs.
Designing Efficient and Accurate Behavior-Aware Mobile Systems (2021)

Polyketides are a broad class of natural products that have received attention from the scientific community because they are a rich mine of bioactive structures. The common thread that binds the class together is the method by which they are synthesized, by large enzymatic complexes called polyketide synthases (PKSs) which display assembly line like organization. A great deal of effort has been put into studying PKSs, but their mechanistic steps are still not perfectly understood. In order to further the study of PKSs and their components, we have developed a series of reactive small molecules that covalently modify specific sites of PKS components. We have shown that b-lactones are able to selectively load holo-acyl carrier proteins (ACPs) with polyketide-like functionality while leaving similarly functionalized components such as the ketosynthase domain virtually untouched. We have also shown that b- lactams are able discriminate between apo- and holo-ACPs and have used this difference in reactivity to develop a method of purifying holo-ACPs. Another b-lactam based probe has been shown to directly modify the active portion of holo-ACPs with malonate-like functionality, and may be starting point for introducing novel functionality into difficult to access sites of polyketides. During the course of these investigations the copper catalyzed azide-alkyne cycloaddition has been used heavily for conjugation reactions involving small molecules and proteins. The presence of copper has been a serious problem, often leading to lost and damaged proteins. Copper-free azide-alkyne conjugation methods exist, but suffer from drawbacks of their own such as slow reaction rates and difficult targetability. In order to maintain the positive aspects of copper free click yet overcome the drawbacks, we have been developing photosensitive probes which upon irradiation rapidly react with azides in a click like reaction. Although this reaction was initially developed with bioconjugation in mind, further experiments have indicated that this may not be the best use. However, experiments are currently being carried out to optimize their performance and explore their usefulness in other chemical conjugation applications.
Multispectral Quantum Dots-in-a-Well Infrared Detectors Using Plasmon Assisted Cavities (2010)

We present the design, fabrication, and characterization, of multi-spectral quantum dots-in-a-well (DWELL) infrared detectors, by the integration of a surface plasmon assisted resonant cavity with the infrared detector. A square lattice and rectangular lattice cavity, formed by modifying the square lattice have been used in this design. By confining the resonant mode of the cavity to detector active region, the detector responsivity and detectivity have been improved by a factor of 5. A spectral tuning of 5.5 to 7.2 ¿m has been observed in the peak response of the detectors, by tuning the lattice constant of the cavity. Simulations indicate the presence of two modes of absorption, which have been experimentally verified. The use of a rectangular lattice predicts highly polarization sensitive modes in <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</i> - and <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">y</i> -direction, which are observed in fabricated detectors. A peak detectivity of 3.1 x 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">9</sup> cm·¿{Hz} /W was measured at 77 K. This design offers a cost-effective and simple method of encoding spectral and polarization information, in infrared focal plane arrays.
Bottom-Up Graphene-Nanoribbon Fabrication Reveals Chiral Edges and Enantioselectivity (2014)

We produce precise chiral-edge graphene nanoribbons on Cu{111} using self-assembly and surface-directed chemical reactions. We show that, using specific properties of the substrate, we can change the edge conformation of the nanoribbons, segregate their adsorption chiralities, and restrict their growth directions at low surface coverage. By elucidating the molecular-assembly mechanism, we demonstrate that our method constitutes an alternative bottom-up strategy toward synthesizing defect-free zigzag-edge graphene nanoribbons.