gebhart/patrepeval huggingface dataset:
Medullary substrate and differential cardiovascular responses during stimulation of specific acupoints (2004)

Electroacupuncture (EA) at P5-P6 acupoints overlying the median nerve reduces premotor sympathetic cardiovascular neuronal activity in the rostral ventral lateral medulla (rVLM) and visceral reflex pressor responses. In previous studies, we have noted different durations of influence of EA comparing P5-P6 and S36-S37 acupoints, suggesting that point specificity may exist. The purpose of this study was to evaluate the influence of stimulating P5-P6 (overlying the median nerve), LI4-L7 (overlying branches of the median nerve and the superficial radial nerve), LI6-LI7 (overlying the superficial radial nerve), LI10-LI11 (overlying the deep radial nerves), S36-S37 (overlying the deep peroneal nerves), or K1-B67 (overlying terminal branches of the tibial nerves) specific acupoints, overlying deep and superficial somatic nerves, on the excitatory cardiovascular reflex and rVLM responses evoked by stimulation of chemosensitive receptors in the cat's gallbladder with bradykinin (BK) or direct splanchnic nerve (SN) stimulation. We observed point-specific differences in magnitude and duration of EA inhibition between P5-P6 or LI10-LI11 and LI4-L7 or S36-S37 in responses to 30-min stimulation with low-frequency, low-current EA. EA at LI6-LI7 and K1-B67 acupoints as well as direct stimulation of the superficial radial nerve did not cause any cardiovascular or rVLM neuronal effects. Cardiovascular neurons in the rVLM, a subset of which were classified as premotor sympathetic cells, responded to brief (30 s) stimulation of the SN as well as acupoints P5-P6, LI10-LI11, LI4-L7, S36-S37, LI6-LI7, or K1-B67, or underlying somatic pathways in a fashion similar to the reflex responses. In fact, we observed a significant linear relationship (r(2) = 0.71) between the evoked rVLM response and reflex change in mean arterial blood pressure. In addition, EA stimulation at P5-P6 and LI4-L7 decreased rVLM neuronal activity by 41 and 12%, respectively, for >1 h, demonstrating that prolonged input into the medulla during stimulation of somatic nerves, depending on the degree of convergence, leads to more or less inhibition of activity of these cardiovascular neurons. Thus EA at acupoints overlying deep and superficial somatic nerves leads to point-specific effects on cardiovascular reflex responses. In a similar manner, sympathetic cardiovascular rVLM neurons that respond to both visceral (reflex) and somatic (EA) nerve stimulation manifest graded responses during stimulation of specific acupoints, suggesting that this medullary region plays a role in site-specific inhibition of cardiovascular reflex responses by acupuncture.
Ion chromatographic determination of anions in wastewater precipitate (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIon chromatographic determination of anions in wastewater precipitateL. W. Green and J. R. WoodsCite this: Anal. Chem. 1981, 53, 14, 2187–2189Publication Date (Print):December 1, 1981Publication History Published online1 May 2002Published inissue 1 December 1981https://pubs.acs.org/doi/10.1021/ac00237a010https://doi.org/10.1021/ac00237a010research-articleACS PublicationsRequest reuse permissionsArticle Views98Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Influence of stoichiometry on the metal-semiconductor transition in vanadium dioxide (1974)

The structure and resistivity of vanadium dioxide films close to the metal-semiconductor transition have been studied as a function of stoichiometry. Unit-cell volume is shown to go through a minimum and the transition temperature and resistivity ratio through a maximum at the apparent stoichiometric oxygen level. The observed resistivities can be accounted for by an increased electron concentration due to vanadium interstitials in the low-oxygen films and by a second phase in the high-oxygen films. The variation of resistivity and transition temperature with electron concentration provides experimental support for the previous suggestion that the driving force of the transition is mainly an antiferroelectric distortion.
Resolvin D1 Reduces Infarct Size Through a Phosphoinositide 3-Kinase/Protein Kinase B Mechanism (2015)

This study was designed to determine if Resolvin D1 (RvD1), a pro-resolution metabolite of the omega-3 polyunsaturated fatty acid docosahexaenoic acid, could decrease myocardial infarct size with delivered at the onset of ischemia. Male Sprague Dawley rats underwent 40 minutes of myocardial ischemia followed by reperfusion. These animals received 1 intraventricular injection of RvD1 (0.01, 0.1, or 0.3 μg RvD1) or vehicle (saline) before coronary occlusion. Infarct size and neutrophil accumulation were evaluated 24 hours after the onset of reperfusion. Caspase-3, caspase-8, protein kinase B (Akt) activities were evaluated 30 minutes after the reperfusion. Rats receiving 0.1 or 0.3 μg RvD1 showed a significant decrease of infarct size and caspase-3 and caspase-8 activities compared with the vehicle controls. Neutrophil accumulations were reduced in rats administered RvD1 compared with vehicle, independently of dose level. Akt activation was increased only in animals receiving 0.1 or 0.3 μg, whereas no change was observed in the 0.01 μg group. When they were treated with LY-294002, a phosphoinositide 3-kinase (PI3K)/Akt inhibitor, cardioprotection by RvD1 was abrogated. RvD1 treatment at the onset of ischemia decreases infarct size by a mechanism involving the PI3K/Akt pathway.
Recovery of Thumb and Finger Extension and Its Relation to Grasp Performance After Stroke (2009)

This study investigated how the ability to extend the fingers and thumb recovers early after stroke and how the ability to extend all of the digits affects grasping performance. We studied 24 hemiparetic patients at 3 and 13 wk post stroke. At each visit, we tested the subjects' ability to actively extend all five digits of their contralesional, affected hand against gravity and to perform a grasp movement with the same hand. Three-dimensional motion analysis captured: 1) maximal voluntary extension excursion of each digit and 2) grasp performance variables of movement time, peak aperture, peak aperture rate, and aperture path ratio. We found that finger and thumb extension improved from 3 to 13 wk, with average improvements ranging from 12 to 19 degrees across the five digits. Grasp performance improved on two of the four variables measured. Peak apertures and peak aperture rates improved from 3 to 13 wk, but self-selected movement time and aperture path ratio did not. Stepwise multiple regression models showed that the majority of variance in grasp performance at 13 wk could be predicted by the ability to extend the index or middle finger at 3 wk, plus the change in the ability to extend the index finger from 3 to 13 wk. R2 values ranged from 0.55 to 0.89. Our data indicate that the amount of recovery in finger and thumb extension and grasping is small from 3 to 13 wk post stroke. In people with relatively pure motor hemiparesis, one important factor underlying deficits in hand shaping during grasping is the inability to extend the fingers and thumb. Without sufficient volitional control of finger and thumb extension, successful grasping of objects will not occur.
Effects of suramin-related and other clinically therapeutic polyanions on protein kinase C activity. (1995)

The mechanism of the antineoplastic effects of suramin may involve interference with signal transduction, but in general is not well understood. We examined several polyanions to determine their effects on the kinase activity of the protein kinase C (PKC) beta1 and other PKC isoforms. Similar to suramin, a phosphorothioate oligodeoxynucleotide 28-mer homopolymer of cytidine (SdC28) inhibited the phosphatidylserine and Ca2+-dependent phosphorylation of an epidermal growth factor receptor octapeptide substrate. The inhibition by suramin was mixed competitive/noncompetitive with respect to ATP, but uncompetitive with respect to substrate. In contrast, the inhibition by SdC28 was competitive with respect to substrate (Ki = 5.4 microM) and not competitive with respect to ATP. The PKC alpha and beta1 isoforms were inhibited to the same extent with SdC28, while PKC epsilon was not inhibited. SdC28, in the absence of lipid cofactor, stimulated substrate phosphorylation, and in the absence of substrate induced PKC beta1 autophosphorylation. Similar behavior was seen with another polyanion, the polysulfated carbohydrate pentosan polysulfate (polyxylyl hydrogen sulfate). H4, a bis-naphthalene disulfonate tetraanion structurally related to suramin, also inhibited kinase activity but was not competitive with respect to ATP. Dianions closely related to H4 failed to inhibit PKC beta1, suggesting that multiple (>2) negative charges are required. The interactions of polyanions with PKC are complex, and are dependent on the molecular structure of the polyanion, the presence of cofactors, and the PKC isoform.
QUARTERLY BOOK-LIST (1957)

Journal Article QUARTERLY BOOK-LIST Get access FRANK C. CAMPBELL FRANK C. CAMPBELL Search for other works by this author on: Oxford Academic Google Scholar The Musical Quarterly, Volume XLIII, Issue 1, January 1957, Pages 143–148, https://doi.org/10.1093/mq/XLIII.1.143 Published: 01 January 1957
Addressing the non-functional requirements of computer vision systems: A case study (2014)

Computer vision plays a major role in the robotics industry, where vision data is frequently used for navigation and high-level decision making. Although there is significant research in algorithms and functional requirements, there is a comparative lack of emphasis on how best to map these abstract concepts onto an appropriate software architecture. In this study, we distinguish between the functional and non-functional requirements of a computer vision system. Using a RoboCup humanoid robot system as a case study, we propose and develop a software architecture that fulfills the latter criteria. The modifiability of the proposed architecture is demonstrated by detailing a number of feature detection algorithms and emphasizing which aspects of the underlying framework were modified to support their integration. To demonstrate portability, we port our vision system (designed for an application-specific DARwIn-OP humanoid robot) to a general-purpose, Raspberry Pi computer. We evaluate performance on both platforms and compare them to a vision system optimised for functional requirements only. The architecture and implementation presented in this study provide a highly generalisable framework for computer vision system design that is of particular benefit in research and development, competition and other environments in which rapid system evolution is necessary.
EPR Investigation of Fe-Exchanged Beta-Zeolites (2003)

Iron-exchanged beta-zeolites with an exchange level (300 Fe/Al, mol/mol) of 10−97 were characterized by electron paramagnetic resonance (EPR) after calcination and a redox pretreatment (H2/N2O). According to the EPR spectra, three different types of iron species are present in the samples: isolated ions, polynuclear oxo-iron species (clusters), and superparamagnetic iron particles. Fe-exchanged beta-zeolites (Fe−BEA) with an iron exchange level lower than 24 are mainly constituted by isolated Fe(III) ions. These latter species can be located in the structure or in charge compensation of the BEA zeolite structure. The amount of interacting species above an iron exchange level of 24 increases strongly, and these species become predominant at an iron exchange level of 100. Oxidation of Fe2+−BEA by N2O leads to the generation of new oxo-iron species with superparamagnetic character. These species are considered as the active species in the selective catalytic reduction of N2O by NH3 over fully exchanged Fe−BEA.
山本有三編『日本少國民文庫』と島崎藤村編『新日本少年少女文庫』に關する一考察 (2008)

Nihon-Syokokumin-Bunko (A Series of Japanese Children’s Literature) edited by YAMAMOTO Yuzo is a 16 volumes series, the first of which - Kokoro-ni-Taiyo-wo-Mote (Have Sun in Your Mind) written by Yamamoto - was published in November 1935 and was completed in August 1937 with Kimitachi-wa-Dou-Ikiruka (How Do You Live?) written by YOSHINO Genzaburo. This series was organized by Yamamoto Yuzo, a playwright, and was published with the help of SATO Giryo at Shinchosha. It was Shinchosha’s first attempt at publishing children’s books. It is said that Yamamoto put a lot of thoughtful preparation into publishing the series, getting advice from KIKUCHI Kan, among others, and making Yoshino Genzaburo and YOSHIDA Kinetaro its editors. Although its main readers were supposed to range from the higher grades in primary school to junior high school children, its significance and unique identity was due to the fact that the series was neither a purely literary series nor a set of encyclopaedias as had been previously published but a self contained and comprehensive series with its own ethics and philosophical identity aimed at cultivating young people’s personalities and building their thinking processes. Generally the series has been lauded as “a symbol of resistance spirit in the period” (*1), “the embodiment of conscientious publication during the war” (*2) and “It should be highly valued for successfully conveying humanism from an international point of view”(*3), there are still some gaps in our knowledge concerning the background to the birth of the plan and the editing process, which will need to be looked into further. This is particularly true when one considers Yamamoto Yuzo, the organizer, whose involvement and subsequently profound participation in children’s literature and culture of the period - from “An Instructive outline concerning the improvement of children’s reading materials” in 1938 to the foundation and inception of Nihon- Syokokumin-Bunka-Kyokai (Japan children (=shokokumin) culture association) in 1941 - was triggered by the series. He had been a school friend of the Prime Minister KONOE Fumimaro, and they had maintained a close friendship ever since, so he was arrested during this period for offering funds to the Communist Party. So the question remains as to what role he actually played in the control and organization of children’s culture groups under the political dynamics of that unstable period. This study considers the role played by Yamamoto Yuzo in the formation of policy on children’s culture after 1938. As an the introduction to the study, this thesis examines Nihon-Syokokumin-Bunko and other related series in which Yamamoto began to be concerned with children’s literature. *1 KAN Tadamichi, Nihon-no-Jidobungaku revised edition, Otsuki-shoten, May 14, 1966. *2 NAMEKAWA Michio, “Explanation for Yoshida Kinetaro” in Nihon-Jidobungaku- Taikei, vol. 24, Holp-Shuppan, November 30, 1978. *3 Edited by Nihon-Jidobungaku-Gakkai, Nihon-Jido-Bungaku-Gairon, Tokyo-Syoseki, April 2, 1976.
Analysis of a quantum logic device based on dipole-dipole interactions of optically trapped Rydberg atoms (2005)

We present a detailed analysis and design of a neutral atom quantum logic device based on atoms in optical traps interacting via dipole-dipole coupling of Rydberg states. The dominant physical mechanisms leading to decoherence and loss of fidelity are enumerated. Our results support the feasibility of performing single- and two-qubit gates at MHz rates with decoherence probability and fidelity errors at the level of ${10}^{\ensuremath{-}3}$ for each operation. Current limitations and possible approaches to further improvement of the device are discussed.
Dynamic Power Control Mechanism for Femtocells Based on the Frame Utilization (2010)

The femtocells are very promising concept for wireless networks to significantly enhance system capacity. Nevertheless, a lot of challenges must be still addressed. The paper focuses on a power control mechanism and proposes a novel approach for dynamic adaptation of transmitting power of femtocell access points. The basic idea is to adapt the transmitting power of femtocells according to current traffic load and signal quality between mobile stations and femtocell in order to fully utilize data frame. The advantage of this approach is its potential to decrease interference to users of macro cell or adjacent femtocells at light traffic load. Performed analytical evaluations of our proposed scheme in comparison to the existing power control mechanisms show that femtocell's transmitting power can be significantly reduced while the same Quality of Service level is still guaranteed to the femtocell users.
Mapping Interleaving Laws to Parallel Turbo Decoder Architectures (2004)

For high data rate applications, the implementation of iterative turbo-like decoders requires the use of parallel architectures posing some collision-free constraints to the reading/writing process in the soft-input soft-output (SISO) decoders. Contrary to the literature belief, we prove in this paper that the parallelism constraints can be met by any permutation law employed by the turbo-interleaver, and we give a constructive method to satisfy those constraints.
The Use of Cylexin (CY-1503) in Prevention of Reperfusion Lung Injury in Patients Undergoing Pulmonary Thromboendarterectomy (2000)

Pulmonary thromboendartectomy (PTE) for chronic thromboembolic pulmonary hypertension may be complicated by reperfusion lung injury. This has previously been demonstrated to be neutrophil-mediated. We postulated that blocking selectin-mediated adhesion of neutrophils to the endothelium with Cylexin (CY-1503) would prevent reperfusion lung injury in this patient population. In this double-blind, randomized, placebo-controlled, parallel study, 26 patients received Cylexin the day of surgery and 25 received placebo. Significantly fewer patients in the treated group (31%) compared with the placebo group (60%) developed lung injury (p = 0.036). However, the average number of days of mechanical ventilation, days in the intensive care unit (ICU) and hospital, as well as mortality were not significantly different between the treatment groups. Those with reperfusion lung injury had significantly elevated percent neutrophils, total protein, and soluble P-selectin in bronchoalveolar lavage fluid compared with those without lung injury. We conclude that reperfusion lung injury after PTE is a high-permeability lung injury and its incidence can be reduced by the administration of Cylexin on the day of surgery.
Design and characterization of low-cost fabric-based flat pneumatic actuators for soft assistive glove application (2017)

We present the design of low-cost fabric-based Hat pneumatic actuators for soft assistive glove application. The soft assistive glove is designed to assist hand impaired patients in performing activities of daily living and rehabilitation. The actuators consist of flexible materials such as fabric and latex bladder. Using zero volume actuation concept, the 2D configuration of the actuators simplifies the manufacturing process and allows the actuators to be more compact. The actuators achieve bi-directional flexion and extension motions. Compared to previously developed inflatable soft actuators, the actuators generate sufficient force and torque to assist in both finger flexion and extension at lower air pressure. Preliminary evaluation results show that the glove is able to provide both active finger flexion and extension assistance for activities of daily living and rehabilitative training.
Allosteric interactions between cyclothiazide and AMPA/kainate receptor antagonists (1996)

1. Cyclothiazide blocks alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization and potentiates AMPA receptor gated currents. Interactions between cyclothiazide, and the non-competitive antagonist GYKI52466 (GYKI) and competitive antagonist 2,3-dihydroxy-6-nitro-7-sulphamoyl-benzo (F) quinoxaline (NBQX) were studied at native and recombinant AMPA/kainate receptors using whole-cell recording in order to characterize the modulation by cyclothiazide of these two antagonist sites. 2. GYKI 100 microM, which is sufficient to eliminate virtually hippocampal kainate (100 microM) currents, failed to prevent access of cyclothiazide to its site of potentiation, and was unable to enhance removal of cyclothiazide potentiation. However, cyclothiazide reduced GYKI (30 microM) block from 84 +/- 8.3% to 38 +/- 12%, and slowed the onset of the block with a time course much faster than the time course for onset and offset of potentiation induced by cyclothiazide. Cyclothiazide had qualitatively similar effects upon antagonism by NBQX 1 microM. 3. Kainate activated desensitizing currents in dorsal root ganglion (DRG) neurones, which were unaffected by cyclothiazide. GYKI blocked these kainate currents with lower affinity (IC50 > 120 microM) than for hippocampal neurones (IC50 < 30 microM), and cyclothiazide did not affect GYKI antagonism. 4. Steady-state AMPA currents from homomeric GluRA-Dflip receptors in HEK 293 cells were dramatically potentiated (up to 216 fold) by cyclothiazide via reduction of desensitization. In contrast, kainate-gated currents in HEK 293 cells expressing GluR6R receptors exhibited pronounced desensitization that was unaffected by cyclothiazide. GYKI retains its inhibition at both recombinant AMPA and kainate receptors. 5. These results indicate that cyclothiazide allosterically influences two important antagonist sites on AMPA receptors. In addition, AMPA/kainate receptor subunit composition influences the affinity of GYKI for the receptor.
Up‐regulation of a novel integrin α‐chain (α<sub>mt</sub>) on human fetal myotubes (1995)

Integrin expression and distribution was studied in cloned human fetal G6 myoblasts and myotubes. Immunoprecipitation of beta 1 integrins from surface iodinated and metabolically labeled G6 cells typically showed a five-fold induction of a beta 1 integrin associated protein upon differentiation. Under non-reducing conditions this beta 1 associated protein migrated as 145 kD. No such beta 1 associated protein was observed in the myogenic L8 rat cell line, before or after differentiation. The beta 1 integrin associated cell surface protein present in G6 myotubes remained associated with the beta 1 subunit in the presence of 1% Triton X-100 and 0.5 M NaCl. Like integrin alpha-chains, the protein dissociated from the beta 1 integrin subunit at low pH. Immunoprecipitation of G6 myotubes further indicated the presence of alpha 1, alpha 3, alpha 5, and alpha v integrins, and small amounts of alpha 4 and alpha 6 integrins. Immunodepletion with integrin alpha-chain antibodies to alpha 1, alpha 3, alpha 4, alpha 5, alpha 6, and alpha v integrin chains could not deplete the beta 1 integrin associated protein, indicating that it did not interact with any of these known integrin heterodimers. Upon treatment with reducing agents, the beta 1 integrin associated protein migrated in SDS-PAGE as a 155 kD protein. The decreased mobility in SDS-PAGE upon reduction is a feature shared with alpha 1, alpha 2, and alpha 9 integrin alpha-chains. Antibodies to alpha 1 immunoprecipitated an integrin heterodimer distinct from the 155 kD protein.(ABSTRACT TRUNCATED AT 250 WORDS)