gebhart/patrepeval huggingface dataset:
A Formalization of Complex Event Stream Processing (2014)

Information systems in general, and business processes in particular, generate a wealth of information in the form of event traces or logs. The analysis of these logs, either offline or in real-time, can be put to numerous uses: computation of various statistics, detection of anomalous patterns or compliance violations of some form of contract. However, current solutions for Complex Event Processing (CEP) generally offer only a restricted set of predefined queries on traces, and otherwise require a user to write procedural code to compute custom queries. In this paper, we present a formal and declarative language for the manipulation of event traces.
Ion milling planarization for magnetic bubble devices (1983)

An ion beam milling technique is used to planarize the SiO2 steps in 8 μm period field-access magnetic bubble devices. A photoresist coating is first applied over the SiO2 steps to produce a smooth surface. The resist layer is then ion milled using conditions that give equal milling rates for the resist and SiO2 films. The planar resist surface is thus preserved in SiO2 after the resist layer is completely milled away. Magnetic bubble devices fabricated by this process are shown to operate at much lower in-plane drive field than similar devices fabricated by conventional nonplanar processes.
An Efficient Wake-Up Strategy Considering Spurious Glitches Phenomenon for Power Gating Designs (2009)

During the power mode transition, simultaneously turning on sleep transistors provides a sufficiently large surge current, which may cause a large IR drop in the power networks. The IR drop in turn causes errors in the retention sequential elements of the sleep modules or errors of the nonsleep modules. One efficient way to control the surge current is to schedule the turn-on sequences of sleep transistors. In this paper, we introduce several important properties of the surge current during the power mode transition for the distributed sleep transistor network (DSTN) design, which is a popular power gating design style. Based on these properties, we propose an accurate estimation of the surge current and provide efficient schedules on the DSTN structure. Our methods achieved significantly better results than previous works-on average, 261 times wake-up time reduction and 30% less energy loss during the power mode transition.
Adaptive medial-axis approximation for sphere-tree construction (2004)

Hierarchical object representations play an important role in performing efficient collision handling. Many different geometric primitives have been used to construct these representations, which allow areas of interaction to be localized quickly. For time-critical algorithms, there are distinct advantages to using hierarchies of spheres, known as sphere-trees, for object representation. This article presents a novel algorithm for the construction of sphere-trees. The algorithm presented approximates objects, both convex and non-convex, with a higher degree of fit than existing algorithms. In the lower levels of the representations, there is almost an order of magnitude decrease in the number of spheres required to represent the objects to a given accuracy.
Mechanical Characteristics of Sn-Ag-Based Lead Free Solders. (2002)

Recently, preventing environmental pollution, lead-free (Pb-free) solders are about to replace tin-lead (Sn-Pb) eutectic solders. However, the mechanical properties of Pb-free solders have not been clarified. Hence, the following study was conducted; First, a rate-dependent plasticity was characterized to represent the inelastic deformation behavior for Sn-Ag-based lead free solders. The material parameters in a constitutive model was determined in a direct method combining both rate dependent and rate independent plastic strains. The constitutive model unifies both rate-dependent creep behavior and rate-independent plastic behavior occurring concurrently at the same time in the solders. Secondly, the strength of solders with a variety of plating materials was studied. Intermetallic compounds between solder and electrical pads are formed during reflow process and gradually grow in service. By using the Cu-plates on which Cu or Ni or Ni/Au plating was deposited, the specimens of solder joints were fabricated with Sn-Ag-based lead free solders. After aging the specimens in an isothermal chamber, tensile tests were performed. From SEM microscope observation and EDX microprobe analysis, the growth and components of the intermetallic compounds layer were also examined. Based on the experimental tests, the relations between solder joint strength and the aging period were discussed.
The retinoblastoma gene and gene product. (1992)

Retinoblastoma, an uncommon childhood cancer of the eye, sometimes occurs in families but is often sporadic. Cytological analysis suggested that the retinoblastoma gene resided on chromosome 13 band q14. Subsequent isolation of the RB gene from this locus allowed a more detailed analysis, showing that both copies of RB are mutated or lost in retinoblastoma, a finding that has been extended to a surprising number of other malignancies. In familial retinoblastoma, one copy of RB is mutant in the conceptus, consistent with the familial predisposition to the disease and indicating that a single wild type copy is sufficient for normal development. These studies provided the first good evidence that loss of a gene function correlated with tumorigenesis and led to the concept of "tumour suppressor genes", which have an important negative influence on the regulation of cell growth. Examinations of the biological properties of the gene product are consistent with this proposed role in cell proliferation. Further insight into the potential molecular mechanisms concerned has come from observations showing an association of some viral oncoproteins with the RB gene product. Thus, there is strong evidence that the RB protein has a key role in the integrated network of signals that control the cell cycle.
Synthesis of New Covalently Bound κ-Carrageenan−AZT Conjugates with Improved Anti-HIV Activities (2002)

This paper describes the first covalent synthesis of kappa-carrageenan-3'-azido-3'-deoxythymidine (AZT) conjugates. A succinate diester spacer was used to covalently couple AZT onto kappa-carrageenan, resulting in a tripartite prodrug. Two methods (UV and radioactive counting) are described and validated to determine the AZT loading onto the kappa-carrageenan carrier. This polymeric carrier, through its own intrinsic anti-HIV activity, is expected to act not only as a drug delivery agent but also as an anti-HIV agent. Synergism between the two drugs (kappa-carrageenan and AZT) was demonstrated when MT-4 cells were preincubated with the kappa-carrageenan-AZT conjugate prior to HIV-1-infection. A threshold of AZT loaded onto the kappa-carrageenan was required to achieve this synergistic effect. Such kappa-carrageenan-AZT conjugates could be of great therapeutic interest because these conjugates, which contain a low AZT concentration, present improved anti-HIV activities relative to free AZT. Moreover, kappa-carrageenan is a well-tolerated biopolymer, already used in the food industry.
Multi-modal Auto-Encoders as Joint Estimators for Robotics Scene Understanding (2016)

We explore the capabilities of Auto-Encoders to fuse the information available from cameras and depth sensors, and to reconstruct missing data, for scene understanding tasks. In particular we consider three input modalities: RGB images; depth images; and semantic label information. We seek to generate complete scene segmentations and depth maps, given images and partial and/or noisy depth and semantic data. We formulate this objective of reconstructing one or more types of scene data using a Multi-modal stacked Auto-Encoder. We show that suitably designed Multi-modal Auto-Encoders can solve the depth estimation and the semantic segmentation problems simultaneously, in the partial or even complete absence of some of the input modalities. We demonstrate our method using the outdoor dataset KITTI that includes LIDAR and stereo cameras. Our results show that as a means to estimate depth from a single image, our method is comparable to the state-of-the-art, and can run in real time (i.e., less than 40ms per frame). But we also show that our method has a significant advantage over other methods in that it can seamlessly use additional data that may be available, such as a sparse point-cloud and/or incomplete coarse semantic labels.
The new development of measuring EHL oil film thickness for thrust bearing (2000)

Through optimizing the electric parameters of the resistance-capacitance (R-C) oscillation, a measuring instrument is developed for measurement of EHL oil film thickness. Actual measurement was made with thrust bearing and actual measurements are in good agreement with theoretical calculations.
Impulse-86: a substrate for object-oriented interface design (1986)

Impulse-86 provides a general and extensible substrate upon which to construct a wide variety of interactive user interfaces for developing, maintaining, and using knowledge-based systems. The system is based on five major building blocks: Editor, Editor Window, PropertyDisplay, Menu , and Operations . These building blocks are interconnected via a uniform framework and each has a well-defined set of responsibilities in an interface. Customized interfaces can be designed by declaratively replacing some of the building blocks in existing Impulse-86 templates. Customization may involve a wide range of activities, ranging from simple override of default values or methods that control primitive operations ( e.g. , font selection), to override of more central Impulse-86 methods ( e.g. , template instantiation). Most customized interfaces require some code to be written—to handle domain-specific commands. However, in all cases, the Impulse-86 substrate provides considerable leverage by taking care of the low-level details of screen, mouse, and keyboard manipulation. Impulse-86 is implemented in Strobe, a language that provides object-oriented programming support for Lisp. This simplifies customization and extension.
Fully Metalated Silsesquioxanes: Building Blocks for the Construction of Catalyst Models (2004)

Versatile building blocks for the construction of molecular models for heterogeneous catalysts are readily available in high yields in the form of fully metalated silsesquioxane derivatives, such as dimeric 1, by using alkali-metal silylamides as deprotonating agents.
trans-dominant inhibition of connexin-43 by mutant connexin-26: implications for dominant connexin disorders affecting epidermal differentiation (2001)

Dominant mutations of GJB2-encoding connexin-26 (Cx26) have pleiotropic effects, causing either hearing impairment (HI) alone or in association with palmoplantar keratoderma (PPK/HI). We examined a British family with the latter phenotype and identified a new dominant GJB2 mutation predicted to eliminate the amino acid residue E42 (DeltaE42) in Cx26. To dissect the pathomechanisms that result in diverse phenotypes of dominant GJB2 mutations, we studied the effect of three Cx26 mutants (DeltaE42, D66H and R75W) identified in individuals with PPK/HI, and another (W44C) present in individuals with non-syndromic HI on gap junctional intercellular communication. We expressed mutant Cx26 alone and together with the epidermal connexins Cx26, Cx37 and Cx43 in paired Xenopus oocytes, and measured the intercellular coupling by dual voltage clamping. Homotypic expression of each connexin as well as co-expression of wild-type (wt) Cx26/wtCx43 and wtCx26/wtCx37 yielded variable, yet robust, levels of channel activity. However, all four Cx26 mutants were functionally impaired and failed to induce intercellular coupling. When co-expressed with wtCx26, all four mutants suppressed the wtCx26 channel activity consistent with a dominant inhibitory effect. However, only those Cx26 mutants associated with a skin phenotype also significantly (P<0.05) inhibited intercellular conductance of co-expressed wtCx43, indicating a direct interaction of mutant Cx26 units with wtCx43. These results demonstrate, for the first time, a trans-dominant negative effect of Cx26 mutants in vitro. Furthermore, they support a novel concept suggesting that the principal mechanism for manifestation of dominant GJB2 mutations in the skin is their dominant interference with the function of wtCx43. This assumption is further corroborated by our finding that Cx26 and Cx43 focally colocalize at gap junctional plaques in affected skin tissue of two carriers of DeltaE42.
The Mechanism of the Anti-Tumor Activity of the Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid (SAHA) (2004)

Histone deacetylases (HDAC) are ubiquitously distributed through chromatin. Nevertheless HDAC inhibitors (HDACi), such as SAHA, selectively alter the transcription of as few as 2–5% of expressed genes in various transformed cells. p21WAF1 is one of the most commonly induced genes in cells cultured with SAHA. Understanding the mechanism of the selective effects of the HDACi is a challenging problem. Gui et al. have identified effects of SAHA on p21WAF1 promotor associated proteins that explain, at least in part, the selective effects of HDAC in altering gene expression (see ref. 1).
A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells. (1992)

Tre is a recombinant gene isolated from NIH3T3 cells transfected with human Ewing's sarcoma DNA. It is composed of three major genetic elements derived, 5' to 3', from human chromosomes 5, 18 and 17. We report here on transcripts from the 3' domain of tre. The transcripts were cloned from a cDNA library of cytoplasmic poly(A)+ RNA from tre-transfected NIH3T3 tumor cells. The complete cDNA sequence, 8201 nucleotides, possessed an unusually long non-coding region and a translatable region with two open reading frames. In one cDNA clone, the presence of two insertions suggested the possibility of alternative splicing. The sequence mapped to the centromere-proximal region of 17q. Transfection-tumorigenicity assays with the open reading frames subcloned into expression vectors were positive for the reading frame adjacent to the 5' non-coding region and negative for the second, downstream, reading frame and the possible alternatively spliced versions of both reading frames. Analysis of the 786 amino acid sequence deduced from the 5' reading frame predicted a highly hydrophilic protein with two charge clusters suggesting nucleic acid-binding properties. When used as probe, the cloned sequence detected RNA transcripts in a wide variety of human cancer cells regardless of their lineage of origin from different tissues, but not in human cells from normal tissue.
Crystal phosphors for storage luminescent screens (1992)

A review is given of the work on photostimulated crystal phosphors as materials of storage luminescent screens used in digital radiography. The properties of barium fluorohalides, particularly of BaFBr : Eu, important in these applications are considered. Much attention is given to the influence of conditions during preparation on these properties, to physicochemical relationships describing the processes of formation and interaction of crystal lattice defects, and to the current ideas on the mechanism of photostimulated luminescence. The bibliography includes 94 references.
Motion synthesis and editing in low‐dimensional spaces (2006)

Abstract Human motion is difficult to create and manipulate because of the high dimensionality and spatiotemporal nature of human motion data. Recently, the use of large collections of captured motion data has added increased realism in character animation. In order to make the synthesis and analysis of motion data tractable, we present a low‐dimensional motion space in which high‐dimensional human motion can be effectively visualized, synthesized, edited, parameterized, and interpolated in both spatial and temporal domains. Our system allows users to create and edit the motion of animated characters in several ways: The user can sketch and edit a curve on low‐dimensional motion space, directly manipulate the character's pose in three‐dimensional object space, or specify key poses to create in‐between motions. Copyright © 2006 John Wiley & Sons, Ltd.
An Investigation of Effective Process Parameters on Phase Transformation Temperature of Nitinol Manufactured by Selective Laser Melting (2014)

It’s well accepted that the thermo-mechanical properties of Nitinol (NiTi) are strongly affected by the material processing. Additive manufacturing has been recently considered as an interesting technique to develop Nitinol devices with sophisticated geometries, which are impossible or very difficult to be produced through typical manufacturing procedures. In the present work, the effect of energy input on the phase transformation temperatures, as the most critical thermal parameters of the shape memory material, of Nitinol parts manufactured by selective laser melting is investigated and discussed.
Transfer Printing of DNA by “Click” Chemistry (2007)

This paper describes a straightforward procedure to immobilize oligonucleotides on glass substrates in well-defined micropatterns by microcontact printing with a dendrimer-modified stamp. The oligonucleotides are efficiently immobilized by "click" chemistry induced by microcontact printing. Acetylene-modified oligonucleotides were treated with an azide-terminated glass slide under the confinement of the dendrimer-modified stamp, without the use of a Cu(I) catalyst. The immobilization is an irreversible, covalent, and one-step reaction that results in stable attachment of the oligonucleotides. Oligonucleotides with the acetylene-modification at the 5' terminus hybridize selectively with full-length, complementary targets. Strands with more than one acetylene linker do not hybridize with complementary strands.
Out-VM monitoring for Malicious Network Packet Detection in cloud (2017)

Cloud security is one of the biggest challenge in today's technological world. Researchers have proposed some solutions for cloud security. Virtual Machine (VM)-level solutions are configured and controlled at VM. They are less robust and can be easily subverted by attackers. In this paper, we propose an out-VM monitoring security approach named as Malicious Network Packet Detection (MNPD) which monitors the VMs from outside at both network and virtualization layer in cloud environment. MNPD performs the behavioral analysis of network traffic at Cloud Networking Server (CNS); providing primary defense from intrusions at network level. MNPD does the VM traffic validation at hypervisor of Cloud Compute Server (CCoS) to detect spoofing attacks, originated from VMs. The non-spoofed packets are further analyzed using behavior analysis of network traffic to detect any abnormality in the virtual traffic; providing second level of defense from intrusions at virtualization level. MNPD employs statistical learning technique (Random Forest) with ensemble of feature selection approach to learn the behavior of traffic patterns. MNPD does not involve overhead incurred in monitoring extensive memory writes or instruction-level traces. It is a more secure solution to detect attacks which never pass through physical interface and hence not detected by traditional IDS. The proposed approach has been validated with latest datasets (UNSW-NB and ITOC) and results seem to be promising.
A metastasis map of human cancer cell lines (2020)

Most deaths from cancer are explained by metastasis, and yet large-scale metastasis research has been impractical owing to the complexity of in vivo models. Here we introduce an in vivo barcoding strategy that is capable of determining the metastatic potential of human cancer cell lines in mouse xenografts at scale. We validated the robustness, scalability and reproducibility of the method and applied it to 500 cell lines<sup>1,2</sup> spanning 21 types of solid tumour. We created a first-generation metastasis map (MetMap) that reveals organ-specific patterns of metastasis, enabling these patterns to be associated with clinical and genomic features. We demonstrate the utility of MetMap by investigating the molecular basis of breast cancers capable of metastasizing to the brain-a principal cause of death in patients with this type of cancer. Breast cancers capable of metastasizing to the brain showed evidence of altered lipid metabolism. Perturbation of lipid metabolism in these cells curbed brain metastasis development, suggesting a therapeutic strategy to combat the disease and demonstrating the utility of MetMap as a resource to support metastasis research.
The medical home bends cost curve. (2012)

While the Affordable Care Act is trying to manage health insurance, as well as mandating coverage, a number of projects around the country are trying to manage the underlying cost of health care. By bringing back the concept of a true primary care physician, who provides 90% of your care and coordinates with your specialists, these programs are bending the curve of health care cost trends. Most are seeing a reduction in emergency room visits and hospital days in the double digits. Others that are taking fee-for-service insurance out of the picture altogether are experiencing even higher reduction rates. The goal is to increase patient health, which includes the patient having an active role in understanding his or her condition, treatment options and self-care strategies. It is estimated that if all Americans had access to a medical home, our nation could save $37 billion annually.
Optoelectronics: theory and practice (1978)

Optoelectronics: theory and practice , Optoelectronics: theory and practice , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Pillars of integrity : the importance of supreme audit institutions in curbing corruption (1998)

Building strong institutions is a central challenge of development and is a key to controlling corruption. Among public institutions, the Supreme Audit Institutions (SAIs) play a critical role, as they help promote sound financial management and thus accountable and transparent government. However, the full potential of the SAI to address corruption has not been exploited, in part because of the lack of understanding of the overall capacity of the SAI. SAIs are well situated to contribute; they are widely viewed as the independent watchdogs of the public interest and, in some countries, they are already putting a greater focus on accountability for “ethics in the public service ” in the scoping of their audit work and also undertaking value-for-money audits. This paper discusses the role of SAIs in promoting accountability and transparency within government, considers some of the factors making for effective SAIs and highlights the linkages between the audit institutions and other “pillars of integrity, ” notably the media and Parliament. The Economic Development i Institute of the World Bank 1998 ii The findings, interpretations, and conclusions expressed in this document are entirely those of the author(s)