gebhart/patrepeval huggingface dataset:
Design and test of an oxygen turbopump for a dual expander cycle rocket engine (1992)

A liquid oxygen (LOX) turbopump with an 860 R gaseous oxygen (GOX) turbine drive was designed for a 3750 lb thrust dual expander cycle rocket engine. This turbopump, which requires no interpropellant seals or system purges, features a 156 hp, single stage, full admission, impulse turbine; an axial flow inducer; a two-stage centrifugal pump with unshrouded impellers; long-life, LOX-lubricated, self-aligning, hydrostatic bearings; and a subcritical rotor design. It is constructed of Monel, a nickel-copper alloy, which has low ignition potential in oxygen. The pump was designed to deliver 34.7 gpm of 4655 psia liquid oxygen at a shaft speed of 75,000 rpm. The dual expander cycle rocket engine and the performance it requires of the LOX turbopump will be discussed as well as the design of the pump, turbine, bearings, and the turbopump rotordynamics. The test program and preliminary test results will also be presented.
Large scale graph-based SLAM using aerial images as prior information (2009)

To effectively navigate in their environments and accurately reach their target locations, mobile robots require a globally consistent map of the environment. The problem of learning a map with a mobile robot has been intensively studied in the past and is usually referred to as the simultaneous localization and mapping (SLAM) problem. However, existing solutions to the SLAM problem typically rely on loop-closures to obtain global consistency and do not exploit prior information even if it is available. In this paper, we present a novel SLAM approach that achieves global consistency by utilizing publicly accessible aerial photographs as prior information. Our approach inserts correspondences found between three-dimensional laser range scans and the aerial image as constraints into a graph-based formulation of the SLAM problem. We evaluate our algorithm based on large real-world datasets acquired in a mixed in-and outdoor environment by comparing the global accuracy with state-of-the-art SLAM approaches and GPS. The experimental results demonstrate that the maps acquired with our method show increased global consistency.
Systems Network Architecture: An overview (1976)

By relieving the user of network management concerns, Systems Network Architecture provides a flexible and extendible structure enabling multiple applications to share a single network. The SNA concepts encourage the distribution of information processing from computers to control units by establishing an environment that is independent of the physical configuration. In geographically dispersed networks, application programs and data bases can be moved from the host to another node closer to the terminal operator. Programmable control units can be optimized to allow persons with little or no data-processing training to utilize computers. The communication system formats and protocols enhance the exchange of information among a diverse group of operators, application programs, and devices. Application programs and devices designed to sNA specifications solve specific problems rather than being involved in the entire communications process. Network users can concentrate their resources on specific applications without understanding the increasingly complex information-processing systems that assist them in their work. CITED
Fabrication of four-probe fine electrodes on an atomically smooth Si(100)-2 × 1-H surface (2004)

Four-probe fine electrodes were fabricated on a Si(100)-2 × 1-H surface using conventional lithographic and scanning-probe nano-fabrication techniques followed by standard cleaning and hydrogenation processes of the surface. It was confirmed by scanning tunnelling microscopy that a Si(100)-2 × 1-H surface is formed in the area except for the fine electrodes. Tunnelling spectroscopy of the electrode surface and electrical conduction measurements of nanoscale wires were performed for evaluating the fabricated electrodes. The results showed that the fabricated fine electrodes are capable of measuring the electrical properties of nanoscale surface objects.
SOA service reuse by design (2008)

Reuse of services in supporting new business processes, in addition to alignment of IT with business functions, is a key motivation in using Service-oriented Architecture (SOA) for developing business solutions. The three key benefits of service reuse are improving agility of solutions by quickly assembling new business processes from existing services to meet changing marketplace needs, reduction of cost by not just avoiding duplication of code for enabling similar business functions across multiple business processes, but also throughout the SOA life-cycle spanning service deployment and management, and also reducing risks by reusing well-tested code and runtime environments. However, currently there are many organizational challenges and lack of accepted SOA solution development methodologies and supporting technical capabilities in customer environments in achieving service reuse. This paper details the key challenges in achieving service reuse, and advocates taking a pro-active position in addressing these challenges by putting in place governing key aspects of service life-cycle and supporting technical capabilities.
Blended acquisition with dispersed source arrays, the next step in seismic acquisition? (2011)

Today, seismic acquisition is carried out with broadband sources. We propose to replace in blended acquisition the traditional broadband sources by narrow‐band versions (think at single airguns and narrowband vibrators), together representing Dispersed Source Arrays (DSA's). The DSA concept allows the use of source depths and spatial sampling intervals that are optimum for the low‐, mid‐ and high‐frequency sources. In addition, because narrow‐band sources are relatively simple, we propose to robotize blended acquisition with unmanned source vessels (marine) and unmanned source vehicles (land). Robotization of blended acquisition with the aid of DSA's may be the next step in improving seismic data quality at less cost.
Formulation Considerations for the Management of Dry Eye Disease (2021)

Dry eye disease (DED) is one of the most common ocular surface disorders characterised by a deficiency in quality and/or quantity of the tear fluid. Due to its multifactorial nature involving several inter-related underlying pathologies, it can rapidly accelerate to become a chronic refractory condition. Therefore, several therapeutic interventions are often simultaneously recommended to manage DED efficiently. Typically, artificial tear supplements are the first line of treatment, followed by topical application of medicated eyedrops. However, the bioavailability of topical eyedrops is generally low as the well-developed protective mechanisms of the eye ensure their rapid clearance from the precorneal space, thus limiting ocular penetration of the incorporated drug. Moreover, excipients commonly used in eyedrops can potentially exhibit ocular toxicity and further exacerbate the signs and symptoms of DED. Therefore, formulation development of topical eyedrops is rather challenging. This review highlights the challenges typically faced in eyedrop development, in particular, those intended for the management of DED. Firstly, various artificial tear supplements currently on the market, their mechanisms of action, as well as their application, are discussed. Furthermore, formulation strategies generally used to enhance ocular drug delivery, their advantages and limitations, as well as their application in commercially available DED eyedrops are described.
Immunological identity of brucella native hapten, polysaccharide B, and yersinia enterocolitica serotype 9 native hapten (1982)

Yersinia enterocolitica serotype 9 contained an antigenic component giving a reaction of total identity with Brucella native hapten and polysaccharide B. This component was present in a phenol-water extract (fraction 5; M. Redfearn, Ph.D. Thesis, University of Wisconsin, Madison, 1960) along with the smooth lipopolysaccharide. The native hapten could be purified free of lipopolysaccharide and proteins by gel filtration.
Brief Probe into the Brand and Marketing Strategy of NBA (2015)

Sports marketing one of many marketing ways which integrates the sports culture and brand culture through sports activities. Sports marketing have two explanations, one regards sports as a commodity, and the other is to regard the sports activities as the carrier of brand marketing. In this paper, we use the second kind of explanation that sports marketing is regarded as a carrier of brand marketing.Nowadays, with the constant development of all kinds of sports, many sports have reached a certain height through their own development strategy and marketing strategy, and form various league and sports leagues, but there isn't one international sports media group like the National Basketball Association (NBA) that is popular all over the world. Marketed through the stars and the surrounding products, the unique marketing strategy is gradually referred to by other league and activities. This article will firstly introduce the current situation of the NBA, expound the importance of sports marketing to brand promotion and sports promotion, then analyze sports marketing strategy, and finally put forward the conclusion of this article and give a summary to this article.
Unequal electron and hole impact ionization coefficients in GaAs (1974)

GaAs Schottky barrier avalanche photodiodes have been fabricated in which it is possible to achieve nearly pure hole and pure electron injection in the same device. Measurements of the multiplication characteristics of these devices show that the ionization coefficients of electrons (α) and holes (β) are not equal and that β&gt;α. This result is in agreement with the variation of multiplication with bias voltage at different wavelengths observed for standard GaAs Schottky barrier diodes but contrary to the generally accepted belief that α=β.
Plasmid transformation of Streptococcus lactis protoplasts: optimization and use in molecular cloning (1984)

The parameters affecting polyethylene glycol-induced plasmid transformation of Streptococcus lactis LM0230 protoplasts were examined to increase the transformation frequency. In contrast to spreading protoplasts over the surface of an agar medium, their incorporation into soft agar overlays enhanced regeneration of protoplasts and eliminated variability in transformation frequencies. Polyethylene glycol with a molecular weight of 3,350 at a final concentration of 22.5% yielded optimal transformation. A 20-min polyethylene glycol treatment of protoplasts in the presence of DNA was necessary for maximal transformation. The number of transformants recovered increased as the protoplast and DNA concentration increased over a range of 3.0 X 10(6) to 3.0 X 10(8) protoplasts and 0.25 to 4.0 micrograms of DNA per assay, respectively. With these parameters, transformation was increased to 5 X 10(3) to 4 X 10(4) transformants per microgram of DNA. Linear and recombinant plasmid DNA transformed, but at frequencies 10- to 100-fold lower than that of covalently closed circular DNA. Transformation of recombinant DNA molecules enabled the cloning of restriction endonuclease fragments coding for lactose metabolism into S. lactis LM0230 with the Streptococcus sanguis cloning vector, pGB301. These results demonstrated that the transformation frequency is sufficient to clone plasmid-coded genes which should prove useful for strain improvement of dairy starter cultures.
Detection and Monitoring of Thermal Lesions Induced by Microwave Ablation Using Ultrasound Imaging and Convolutional Neural Networks (2019)

Microwave ablation (MWA) for cancer treatment is frequently monitored by ultrasound (US) B-mode imaging in the clinic, which often fails due to the low intrinsic contrast between the thermal lesion and normal tissue. Deep learning, especially convolutional neural network (CNN), has shown significant improvements in medical image analysis. Here, we propose and evaluate an US imaging based on a CNN architecture for the detection and monitoring of thermal lesions induced by MWA in porcine livers. Unlike dealing with images in many visual object recognition tasks, US radiofrequency (RF) data backscattered from the ablated region were utilized to capture features related to the thermal lesion. The dataset comprised of 1640 US RF envelope data matrices and their corresponding gross-pathology images, and were utilized for training and testing. After envelope detection, US B-mode, segmentation results based on CNN (SI<sub>CNN</sub>), and modified CNN (SI<sub>m-CNN</sub>) for US data were simultaneously reconstructed to reveal the suitability for monitoring of MWA. The SI<sub>CNN</sub> and SI<sub>m-CNN</sub> outperformed B-mode images for the detection and monitoring of MWA-induced thermal lesions. The values of the area under the receiver operating characteristic curve were 0.8728 and 0.8948 for the SI<sub>CNN</sub> and Si<sub>m-CNN</sub>, respectively, which were both higher than the value of 0.6904 for B-mode images. Ablated regions that were assessed using SI<sub>m-CNN</sub> showed a good correlation (J 0.8845, r 0.8739, and E 0.410) to gross-pathology images. This study was the first to illustrate that SI<sub>m-CNN</sub> has the potential to detect and monitor thermal lesions, and may be utilized as an alternative modality for image-guided MWA treatments.
The effects of engineering measures on safety at adjacent sites (1992)

This paper addresses the question of whether 'accident migration' occurs because of treatment or in spite of treatment. Data are presented which demonstrate that, while accident migration can arise in spite of treatment, accident migration does arise because of treatment and that the size of the effect is of sufficient magnitude to be considered to be of both statistical and practical significance. Language: en
Generalized Cannon's algorithm for parallel matrix multiplication (1997)

Article Generalized Cannon's algorithm for parallel matrix multiplication Share on Authors: Hyuk-Jae Lee Department of Computer Science, Louisiana Tech University, Ruston, LA Department of Computer Science, Louisiana Tech University, Ruston, LAView Profile , James P. Robertson School of Electrical and Computer Engineering, Purdue University, W. Lafayette, IN School of Electrical and Computer Engineering, Purdue University, W. Lafayette, INView Profile , José A. B. Fortes School of Electrical and Computer Engineering, Purdue University, W. Lafayette, IN School of Electrical and Computer Engineering, Purdue University, W. Lafayette, INView Profile Authors Info & Claims ICS '97: Proceedings of the 11th international conference on SupercomputingJuly 1997 Pages 44–51https://doi.org/10.1145/263580.263591Online:11 July 1997Publication History 19citation2,818DownloadsMetricsTotal Citations19Total Downloads2,818Last 12 Months46Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Factors Affecting Feed Efficiency of Dairy Cows (2008)

Feed efficiency (FE) is a concept that has gained popularity in recent years in the dairy industry. Monitoring FE is becoming a more common benchmark for monitoring the profitability of milk production relative to dry matter (DM) intake. In today’s markets, feeds and commodities are becoming more costly, which is driving the requirement for more efficient utilization to maintain profitability. The goal of the dairy operation should be to maximize the efficiency of converting feed into milk, which adds the caveat of reducing manure production as well. How efficiently a dairy cow converts feed into milk can affect the dairy operation’s bottom line, which during tough economic conditions, can be the difference between producing milk at a profit or a loss. Other livestock industries have used FE as a benchmark for profitability. Many articles have been written on what FE is, how to measure and calculate FE, and what factors influence FE. This presentation will be to focus the discussion on those biological mechanisms that control the efficient utilization of feeds by the dairy cow, especially DM and fiber digestibility. The understanding of these fundamental mechanisms will enable management decisions on the dairy operation to be implemented that will further improve or enhance FE.
Production of Antibodies against ADP‐ribose and 5′‐AMP with the Aid of <i>N</i><sup>6</sup>‐Carboxymethylated ADP‐ribose Conjugates (1978)

Adenosine diphosphate ribose (ADP‐ribose) coupled directly to bovine serum albumin by the carbodiimide method resulted in a low production of antibodies with a preferential affinity for 5′‐AMP. To allow condensation of the ADP‐ribose residue in a more specific manner, conjugates of N 6 ‐carboxymethylated ADP‐ribose (cm 6 ADP‐ribose) and serum albumin were synthesized in two ways. First, adenine‐N 6 ‐carboxymethylated NAD (cm 6 NAD) was coupled by carbodiimide to serum albumin nearly exclusively through the carboxyl group as judged from a comparison of the epitope density (number of haptens/albumin) of the conjugate with an antigen prepared from unmodified NAD. However, only incomplete enzymic transformation of the NAD hapten to an ADP‐ribose hapten could be achieved due presumably to steric hindrance. Second, cm 6 ADP‐ribose was synthesized from cm 6 NAD by treatment with NAD glycohydrolase. This novel compound was coupled to serum albumin or to methylated serum albumin with the aid of carbodiimide. Only conjugates obtained with the last‐mentioned protein acceptor elicited significant titers of ADP‐ribose antibodies besides a similarly high production of 5′‐AMP antibodies. With cm 6 ADP‐ribose coupled to non‐methylated serum albumin, 5′‐AMP antibodies were produced exclusively, which showed an excellent discrimination between 5′‐AMP and 3′‐AMP, or AMP residues in nucleic acids. Production of 5′‐AMP antibodies was presumably caused by hydrolytic breakdown of the ADP‐ribose antigen in the recipient animals.
Research and development at the Marshall Space Flight Center Neutral Buoyancy Simulator (1987)

The Neutral Buoyancy Simulator (NBS), a facility designed to imitate zero-gravity conditions, was used to test the Experimental Assembly of Structures in Extravehicular Activity (EASE) and the Assembly Concept for Construction of Erectable Space Structures (ACCESS). Neutral Buoyancy Simulator applications and operations; early space structure research; development of the EASE/ACCESS experiments; and improvement of NBS simulation are summarized.
Macular hole and myopic refraction (2002)

Macular hole develops in eyes with the severer myopia at the younger age. Myopic refraction appears not to influence the size and surgical outcomes of macular holes. Further investigation on more cases is needed.
In-Se Based Phase Change Reversible Optical Recording Film (1987)

In-Se based amorphous-crystalline phase change recording films are analysed in terms of structure, optical properties, crystallization speed, and crystallization activation energy. Crystallization by a laser beam is possible by a 0.2μs pulse. Crystallization temperature(heating rate 5°/C min.) measured by using a differential scanning calorimeter is 135°C and crystallization activation energy is calculated to be 2.6eV. The life of the amorphous state is estimated6 to be longer than 10 years at 60°C. The phase change cycles can continue even after 10 cycles in stationary state experiments for test samples. In addition, possibility of single beam overwrite(rewriting without prior erasing) is verified by using a 1.6 μm-diameter round laser beam spot on a 5-inch-diameter disk rotating at 2400rpm. The laser beam power is modulated at 1.77MHz and 0.88MHz between an amorphizing power level and a crystallizing power level. The amorphizing power level is 14mW and the crystallizing power level is 7mW. The experimental results show that the overwrite the same as magnetic disk is possible by using the In-Se based recording film.
Systematic Evaluation of Chimeric Marker Genes on Dicistronic Transcription Units for Regulated Expression of Transgenes <i>In Vitro</i> and <i>In Vivo</i> (1996)

Plasmid expression vectors combining human cytokine cDNAs and selectable marker genes on dicistronic transcription units were functionally characterized in vitro and in vivo. The internal ribosome entry sequence (IRES) of encephalomyocarditis virus mediated cap-independent translation of the downstream cistron. After cationic lipofection of cells with a dicistronic construct containing the Neor gene downstream of a human interleukin-2 (IL-2) cDNA, all G418-resistant clones secreted high amounts of IL-2. Reversal of the order of the cDNAs was associated with less efficient transgene expression and represented no advantage in comparison to separate expression cassettes. To combine direct in vitro selection of expression with in vivo elimination of cytokine-secreting cells, an improved chimeric cDNA of the Neor and herpes simplex virus (HSV) thymidine kinase (TK) genes was constructed and shown to confer sensitivity to ganciclovir concentrations that can be achieved in human patients. This chimeric marker was coupled on dicistronic constructs with a granulocyte colony-stimulating factor (G-CSF) cDNA as a molecule with easily detectable bioactivity in vivo. Subcutaneous implantation of pCMV.GCSF.ires TK/NEO-transfected CMS-5 cells into syngeneic BALB/c mice resulted in excessive leukocytosis and progressively growing tumors. Treatment with ganciclovir led to normalization of leukocyte counts in all animals, whereas complete regression of tumors was observed in only 3/5 mice. Hypermethylation of the transfected promoter was demonstrated in both ganciclovir-resistant tumors. Thus, transcription units combining selectable markers and genes of interest allow selection of high producer cells in vitro and efficient elimination of transgene-expressing cells in vivo. However, cells that hypermethylate transfected genes to terminate gene expression in vivo may escape conditional ablation.
Human pharmacokinetics of N-L-leucyl-doxorubicin, a new anthracycline derivative, and its correlation with clinical toxicities (1992)

A pharmacokinetic study of N-L-leucyl-doxorubicin, a new derivative of doxorubicin, has been undertaken during a phase I trial in 19 patients with advanced cancer after intravenous bolus administration at doses ranging from 30 to 240 mg/m2. The pharmacokinetics of N-L-leucyl-doxorubicin was linear with a total body clearance of 41.3 +/- 25.7 L/hr/m2. N-L-leucyl-doxorubicin was extensively metabolized into doxorubicin, which appeared in plasma immediately after N-L-leucyl-doxorubicin infusion. The mean molar doxorubicin/N-L-leucyl-doxorubicin area under the curve (AUC) ratio was 0.49 +/- 0.22 and was independent of the administered dose. A relationship has been established between the doxorubicin AUC (r = 0.74; p less than 0.001) and the surviving factor in white blood cell counts. Other toxic side effects (thrombocytopenia or stomatitis) did not correlate with any pharmacokinetic parameter. These findings suggest that the degree of metabolization of N-L-leucyl-doxorubicin into doxorubicin may be responsible for the toxicity, that is, N-L-leucyl-doxorubicin may simply represent a pro-drug for doxorubicin.