gebhart/patrepeval huggingface dataset:
Synthesis and Characterization of Quinoidal Diketopyrrolopyrrole Derivatives with Exceptionally High Electron Affinities (2017)

Open-shell singlet biradicaloids are short-lived intermediates, but they exhibit fascinating properties for spin-based devices. Therefore, understanding the nature of their electronic structure and stability is critical for harnessing them in optoelectronic or spintronic devices. Toward this goal, we have synthesized a series of diketopyrrolopyrrole-based quinoidal molecules to investigate the contribution and relative importance of the biradical form on the ground-state electronic structure and distribution of spin density. Possibility of crossover from a closed-shell to an open-shell structure with increase in the C=C/C-C conjugation length was investigated. The ground-state properties were systematically investigated by nuclear magnetic resonance (NMR) spectroscopy, single-crystal X-ray diffraction, and electrochemical studies. Furthermore, n-doping has been carried out in solution at ambient conditions to understand the nature of doped species and demonstrate air stability. Doped species were probed by UV-visible and electron spin resonance (ESR) spectroscopy to unambiguously establish the generation of anionic species in solution. Experimental results are complemented by theoretical calculations to provide insight into the trend toward biradicaloid spin states with increasing conjugation length.
The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression (2003)

Interaction of platelets with collagen under conditions of blood flow is a multi-step process with tethering via glycoprotein IbIXV (GPIbIXV) over von Willebrand factor, adhesion by direct interaction with the integrin GPIaIIa, and signaling via GPVI. GPVI can be specifically agonized by cross-linked collagen-related peptide (CRP-XL), which results in a signaling cascade very similar to that evoked by native collagen. The GPVI gene has 2 common alleles that differ by 3 replacements in the glycosylated stem and 2 in the cytoplasmic domain. We used CRP-XL to elucidate the variation in responses observed in platelet function in different individuals. We observed a 3-fold difference in the response to CRP-XL in platelet aggregation when comparing platelets from 10 high-frequency allele homozygotes with 8 low-frequency ones (2-way analysis of variance [ANOVA], P <.0001). The difference in functional responses was reflected in fibrinogen binding and in downstream signaling events as measured by tyrosine phosphorylation, the expression of P-selectin, and the binding of annexin V and the generation of thrombin on the platelet surface (2-way ANOVA, P <.001). Platelets homozygous for the low-frequency allele tended to be less able to form a thrombus on a collagen surface in flowing whole blood or in the platelet function analyzer-100 (t test, P =.065 and P =.061, respectively). The functional difference was correlated to a difference in total and membrane-expressed GPVI measured by monoclonal and polyclonal antibodies. This study demonstrates for the first time that platelet function may be altered by allelic differences in GPVI.
UHF propagation prediction for wireless personal communications (1994)

Propagation characteristics of radio signals in the UHF band place fundamental limits on the design and performance of wireless personal communications systems, such as cellular mobile radio (CMR), wireless LANs, and personal communication services (PCS). Because the radio link is direct to each subscriber, the prediction of signal characteristics is most important in urban areas where subscriber density is high, and the buildings have a profound influence on the propagation. The paper starts by reviewing the characteristic signal variations observed in CMR systems employing high base station antennas to cover macrocells having radius out to 20 km. Theoretical models incorporating diffraction are shown to explain the observed range dependence and shadow loss statistics. For the low base station antennas envisioned to cover microcells of radius out to 1 km for PCS applications, signal propagation is more strongly dependent on the building environment and on the location of the antennas in relation to the buildings. Various levels of theoretical modeling of this dependence are discussed in conjunction with measurements made in various building environments. Finally, the paper discusses advances in site specific prediction for outdoor and indoor propagation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Long-Term, Wide-Band Spectral Monitoring in Support of Dynamic Spectrum Access Networks at the IIT Spectrum Observatory (2008)

This paper describes the development, deployment and early results of a long-term, wide-band (30 MHz - 6 GHz) spectrum observatory system focused on downtown Chicago and the immediately surrounding areas. Previous short term studies have indicated that more than 80% of the spectral capacity may be unused, even in United States urban centers. The goals of this research effort include the validation of these early results, the understanding of trends in spectral usage over long periods (years), the observation of usage patterns and anomalies, and the detection of the positions of spectral "holes" in time and space. The current status in the attainment of these goals will be shared in this paper. This information, once obtained, vetted and appropriately analyzed will be extremely useful in the development of cognitive radios and other dynamic access network systems, and in the proper establishment of policies and regulations to govern the deployment of such systems.
Purification and Characterization of Glycyrrhetic Acid Mono-glucuronide .BETA.-D-Glucuronidase in Eubacterium sp. GLH. (1999)

Glycyrrhetic acid mono-glucuronide (GAMG), 1-(18beta-glycyrrhet-3-yl)-beta-D-glucopyranuroic acid, was hydrolyzed to glycyrrhetic acid (GA) by GAMG beta-D-glucuronidase in Eubacterium sp. GLH from human intestinal bacteria. The enzyme had an optimum pH of 5.0 and was purified from a crude extract by Butyl Toyopearl 650 S, Toyopearl HW-55 S, Hydroxyapatite and DEAE-Toyopearl 650 M column chromatography. The purified enzyme showed a specific activity of 495 nmol/min/mg protein and a single band on Coomassie brilliant blue staining and a molecular weight of about 43 kDa on sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis. The apparent molecular weight was 49.5 kDa, as estimated by Toyopearl HW-55 S column chromatography. Also, the enzyme seemed to have a sulfhydryl group(s) in its active site with a Km value of 77 x 10(-3) M.
Insolation Forecasting Using Weather Forecast with Weather Change Patterns (2007)

This paper reports an insolation forecasting method for photovoltaic power predictions. The method of proposal forecasts the global irradiance every one hour by using weather forecast every three hours. The weather forecast is classified into 14 kinds of weather change categories by weather change patterns, and the insolation forecasting accuracy is improved. The forecasting accuracy was examined based on the measurement data and the weather forecast announced in Tokyo. In the result, using weather change patterns decrease mean absolute error ratio of hourly forecasting from 32.6 to 30.2% and the error ratio of daily forecasting from 24.7 to 23.5%. The result also shows the possibility that the error ratio of hourly forecasting is decreased to 24.5% and the error ratio of daily forecasting is decreased to 17.8% in Tokyo when the weather forecast accuracy is improved.
Corrosion resistance of type 316 stainless steel to Li/sub 2/BeF/sub 4/. [66-34 Mole % LiF--BeF/sub 2/] (1977)

The corrosion rate of type 316 stainless steel in molten LiF-BeF/sub 2/ (66-34 mole percent) has been measured in a thermal convection loop operating with a maximum temperature of 650/sup 0/C and a temperature difference of 160/sup 0/C. The corrosion rate was correlated with the concentration of impurities in the salt and with the fluoride ion oxidation potential as determined by an on-line voltameter. A corrosion rate of -10 ..mu..m/year was observed initially in the as-received salt. This rate decreased as reactions with initial salt impurities went to completion. Direct addition of beryllium metal to the salt further reduced the corrosion rate.
Depth-Detection Methods for CNT Manipulation and Characterization in a Scanning Electron Microscope (2007)

Current research work on the development of a nanorobot station for the manipulation and characterization of carbon nanotubes is presented. Therefore two nanorobots are cooperating in the vacuum chamber of a scanning electron microscope (SEM). One robot is carrying a nanogripper and is used for the coarse positioning. The second robot serves as sample holder and realizes the fine positioning. In the course of automatic handling tasks, depth-detection within the SEM is required. Two different methods for the z-position estimation of gripper and carbon nanotube are proposed. On the one hand a depth from focus method using real-time processing of noisy SEM images and on the other hand a touchdown sensor concept based on a bimorph piezo bending actuator. Both methods are described in a theoretical framework and are partly verified by experimental tests.
Smartphones and android internals (2013)

This thesis is focused on a detailed study of smart phones with Android operating system in particular. It is focused on Android, covering its history, basics, various features, architecture etc. Not only professionals but every tech. literate person are using smart phones and rely on them for their daily tasks. Android operating system has created a benchmark for smart phone operating systems. This is clearly depicted in recent surveys on market domination among smart phone Operating Systems. Android applications are cataloged for general use on an online market place and can be downloaded via a web connection by owners of Android Smartphone. The numbers of applications are increasing rapidly. The main reason behind its success is that Android is open-sourced and its programming is highly leveraged from Java. The research work has been presented in an easy to understand and lucid manner and requires no pre-requisite knowledge about Android OS. This thesis attempts to introduce new Android developers to different Android flavors, its features and Android architecture. It also provide detailed assistance in certain areas such as Android boot up process, radio interface layer, Attention Commands, logging and debugging mechanism, and upgrade for the Android devices. At this time, there is a paucity of texts to perform these functions. This thesis is very useful, for those who are not familiar to Android. It introduces Android as a benchmark among other mobile operating systems, Android versions, and the different software layers interacting within the device. Nowadays each smartphone has an upgrade ability. We discuss different types of upgrades and their working mechanisms. We have tried to provide further details informing the consumers as well as developers about the process of analyzing an issue or a flaw detected during test procedures and how logging and debugging methods related to android would be helpful in finding the root cause of the error.
Computer-Based Thermographic Displays and Real-Time Techniques (1973)

Nondestructive test methods have traditionally been involved in the detection of localized or point defects such as cracks, voids, and inclusions. However, there has been an increasing demand for meaningful NDT methods that characterize material properties over large surface areas or within the entire volume of a component or structure. Infrared techniques, which lend themselves to area and volume coverage, have been refined for this purpose to a high degree. Simultaneously, there has been a major effort to increase the effectiveness and utility of the large amounts of data resulting from IR scans. This paper concentrates on data enhancement methods, using both real-time and computer-treatment techniques. The data reduction methods covered are significant departures from present NDT data presentations and are aimed primarily at the major ``IR customers''-the materials and design engineers.
3‘-Azido-3‘-deoxythymidine-(5‘)-tetraphospho-(5‘)-adenosine, the Product of ATP-Mediated Excision of Chain-Terminating AZTMP, Is a Potent Chain-Terminating Substrate for HIV-1 Reverse Transcriptase (2006)

The resistance of HIV-1 to 3'-azido-3'-deoxythymidine (AZT) involves phosphorolytic excision of chain-terminating AZT-5'-monophosphate (AZTMP). Both pyrophosphate (PPi) and ATP act as excision substrates in vitro, but the intracellular substrate used during replication of AZT-resistant HIV is still unknown. PPi-mediated excision produces AZT-5'-triphosphate (AZTTP), which could be immediately re-used as a substrate for viral DNA chain termination. In contrast, ATP-mediated excision produces the novel compound AZT-(5')-tetraphospho-(5')-adenosine (AZTp4A). Since little is known of the interaction of AZTp4A with HIV-1 RT, we carried out kinetic and molecular modeling studies to probe this. AZTp4A was found to be a potent inhibitor of HIV-1 RT-catalyzed DNA synthesis and of both ATP- and PPi-mediated AZTMP excision. AZTp4A is in fact an excellent chain-terminating substrate for AZT-resistant RT-catalyzed DNA synthesis, better than AZTTP (k(pol)/Kd = 6.2 and 11.9 for AZTTP and AZTp4A, respectively). The affinity of AZT-resistant HIV-1 RT for AZTp4A is at least 30,000-fold greater than that for the excision substrate ATP and approximately 10-fold greater than that for AZTTP. Dissociation of newly formed AZTp4A from RT may therefore provide a significant rate-limiting step for continued HIV-1 DNA synthesis. Our studies show that the products of PPi- and ATP-mediated excision of chain-terminating AZTMP (AZTTP and AZTp4A, respectively) are both potent chain-terminating substrates for HIV-1 RT, suggesting that there is no obvious benefit to HIV using ATP instead of PPi as the excision substrate.
Application of poly(methacrylic acid‐ethylene glycol dimethacrylate) monolith microextraction coupled with capillary zone electrophoresis to the determination of opiates in human urine (2006)

A novel poly(methacrylic acid-ethylene glycol dimethacrylate) (MAA-EGDMA) monolith microextraction method coupled with CZE was proposed for rapidly determining a mixture of opiates comprising heroin, 6-monoacetylmorphine, morphine, codeine, papaverine, and narcotine in human urine. The extraction device contained a regular plastic syringe, the poly(MAA-EGDMA) monolithic capillary tube (530 microm id x 3 cm) and a plastic pinhead, which connected the monolithic capillary tube and the syringe without leakage. In the polymer monolith microextraction, the sample solution was ejected via the monolithic capillary tube by a programmable syringe pump, followed by desorption with an aliquot of appropriate solution, which was collected into a vial for the subsequent analysis by CZE. The best separation was achieved using a buffer composed of 0.1 M disodium hydrogen phosphate (adjusted to pH 4.5 with 1 M hydrochloric acid) and 20% methanol v/v with temperature and voltage of 25 degrees C and 25 kV, respectively. By applying electrokinetic injection with field-enhanced sample stacking, detection limits of 6.6-19.5 ng/mL were achieved. Excellent method of reproducibility was found over a linear range of 80-2000 ng/mL.
LEITURA MERLEAU-PONTYANA DA TEORIA FENOMENOLÓGICA DA EXPRESSÃO (2000)

A tese de Husserl - segundo a qual,os signos (expressivamente empregados) haveriamde encarnar nossos pensamentos - forneceuo ponto de partida ao projeto merleau-pontyanode restituição "filosófica" de nosso contato com omundo da percepção. Porquanto seriam gestosinstituídos por nosso corpo, os signos (expressivamenteempregados) remeteriam a reflexãofilosófica à experiência sensível e, conseqüentemente,ao mundo da percepção revelado por essaexperiência. Mais do que isso, os signos (expressivamenteempregados) esclareceriam a origemsensível dos pensamentos. O que acabaria porsuspender a própria tese fenomenológica de queos pensamentos seriam o desdobramento dosatos de uma consciência pura. A interpretaçãomerleau-pontyana da teoria fenomenológica daexpressão mostrou que, tal como ôs pensamentos,a consciência de nós mesmos seria tributáriada experiência sensível.
Glycosylation of Glycolipids in Cancer: Basis for Development of Novel Therapeutic Approaches (2013)

Altered networks of gene regulation underlie many pathologies, including cancer. There are several proteins in cancer cells that are turned either on or off, which dramatically alters the metabolism and the overall activity of the cell, with the complex machinery of enzymes involved in the metabolism of glycolipids not being an exception. The aberrant glycosylation of glycolipids on the surface of the majority of cancer cells, associated with increasing evidence about the functional role of these molecules in a number of cellular physiological pathways, has received considerable attention as a convenient immunotherapeutic target for cancer treatment. This has resulted in the development of a substantial number of passive and active immunotherapies, which have shown promising results in clinical trials. More recently, antibodies to glycolipids have also emerged as an attractive tool for the targeted delivery of cytotoxic agents, thereby providing a rationale for future therapeutic interventions in cancer. This review first summarizes the cellular and molecular bases involved in the metabolic pathway and expression of glycolipids, both in normal and tumor cells, paying particular attention to sialosylated glycolipids (gangliosides). The current strategies in the battle against cancer in which glycolipids are key players are then described.
75. Oxidation of polyhalogeno-compounds. Part III. Thermal oxidation of some chlorofluoroethanes (1959)

R. N. Haszeldine and F. Nyman, J. Chem. Soc., 1959, 420 DOI: 10.1039/JR9590000420
REVIEWS SADED.-A.-F.: Les Infortunes de la Vertu. Chronologie et préface par GOULEMOTJEAN-MARIE. (Texte Intégral, 214). Paris: Garnier-Flammarion; London: Harrap. 1969. 186 pp. 32½p. (1971)

Journal Article REVIEWS Get access D.-A.-F. SADE: Les Infortunes de la Vertu. Chronologie et préface JEAN-MARIE par GOULEMOT. (Texte Intégral, 214). Paris: Garnier-Flammarion; London: Harrap. 1969. 186 pp. 32½p. DAVID WILLIAMS DAVID WILLIAMS MCMASTER Search for other works by this author on: Oxford Academic Google Scholar French Studies, Volume XXV, Issue 4, October 1971, Pages 468-a–468, https://doi.org/10.1093/fs/XXV.4.468-a Published: 01 October 1971
Management of febrile neutropenia in the United Kingdom: time for a national trial? (2005)

Recent advances in febrile neutropenia (FN) have highlighted the value of risk stratification and the evolving role of oral antibiotics with early hospital discharge in low-risk patients. The aim of this study was to survey whether these advances have been translated into routine clinical practice in the UK. Questionnaires were sent to cancer clinicians across the UK to determine clinicians' routine management of FN, including use of risk stratification, antibiotic regimen and criteria for hospital discharge. In all, 128 clinicians responded, representing 50 cancer departments (83%). Only 38% of respondents stratify patients according to risk and with substantial variation in the criteria defining 'low-risk'. Furthermore, only 22% of clinicians use oral antibiotics as first-line treatment in any patients with FN, but this was significantly greater among clinicians who do compared to those who do not stratify patients by risk, 51 vs 4% (P<0.0001). These findings suggest a slow and/or cautious introduction of newer strategies for the management of low-risk FN in the UK. However, 84% of respondents confirmed their willingness to participate in a trial of oral antibiotics combined with early discharge in low-risk FN.
An Optical And RF Telemetry Drug Injection Control And ECG System For Awake Small Animal Studies (2005)

A closed-loop remote control drug injection and electrocardiogram(ECG) telemetry system has been developed for chronic unrestrained small animal studies. The infrared-controlled injector unit, carried in an animal backpack, consists of a motorized syringe pump and a frequency-multiplexed radio telemetry circuit for transmission of the ECG signal and drug delivery feedback information. The microprocessor-based remote control transceiver unit transmits command signals to the injector via an infrared beam. Feedback control insures that the actual injection sequence agrees with programmed drug volume, number of injections, and injection interval values. The 3 x 4 x 5 cm injector, with batteries, weighs 70 g. The circuit employs 6 standard CMOS ICs and 5 transistors.
Behavioral Biometrics: A Remote Access Approach (2008)

With the advent of the internet as a medium for performing business transactions, the need for a secure communication channel has never been more paramount. The study of behavioral biometrics - the verification and/or identification of individuals based on the way they provide information to an authentication system - originated from the need for a small footprint, versatile alternative to expensive hardware-based, or physiological, biometrics. As an emerging alternative to these traditional and more well-known physiological biometrics such as fingerprinting or iris scans, behavorial biometrics can offer state-of-the-art solutions to identity management requirements as either a stand-alone system or part of a multi-biometric security system.Whilst there are many existing texts that focus on physiological biometrics or algorithmic approaches deployed in biometrics, Behavioral Biometrics addresses a gap in the existing literature for a text that is solely dedicated to the topic of behavioral biometrics. The authorpresents a thorough analysis of the latest research into well-known techniques such as signature verification and voice recognition, as well more recently developed and ground-breaking techniques including keyboard/ mouse dynamics, gait analysis, odour analysis and salinity testing, which are ever increasing in reliability; discusses exciting future trends that focus on the brain-computer interface using EEG technology and may one day enable human-machine interaction via brainwave patterns; describes the central applications for the technology within e-commerce and related industries, and provides a number of comprehensive case studies of major implementations that provide the user with a strong sense of the approaches employed in the various subdomains of behavioral biometrics. provides a comprehensive glossary of terms as well as a rich set of references and websites that enable the reader to explore and augment topics as required. Behavioral Biometrics will appeal to graduate and postgraduate students, as well as researchers wishing to explore this fascinating research topic, in areas of biometrics and computer science including classification algorithms, pattern recognition, artificial intelligence & security and digital forensics. In addition, it will serve as a reference for system integrators, CIOs, and related professionals who are charged with implementing security features at their organization.