gebhart/patrepeval huggingface dataset:
Coda: a highly available file system for a distributed workstation environment (2003)

A description is given of Coda, a file system for a large-scale distributed computing environment composed of Unix workstations. It provides resilience to server and network failures through the use of two distinct but complementary mechanisms. One mechanism, server replication, involves storing copies of a file at multiple servers. The other mechanism, disconnected operation, is a mode of execution in which a caching site temporarily assumes the role of a replication site. Disconnected operation is particularly useful for supporting portable workstations. The design of Coda optimizes availability and performance and provides the highest degree of consistency attainable. Measurements from a prototype show that the performance cost of providing high availability in Coda is reasonable.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Proteomics Approach to Find Biomarkers in Gastric Cancer (2003)

Gastric cancer is a very serious disease and is naturally resistant to many anticancer drugs. To reduce the mortality and improve the effectiveness of therapy, many studies have tried to find key biomarkers. Proteomic technologies are providing the tools needed to discover and identify disease-associating biomarkers. The proteomic study of gastric cancer establishes any specific events that lead to cancer, and it provides a direct way to define the true function of genes. Using two dimensional (2-D) electrophoresis of the stomach cancer tissue, we have gained about 1,500 spots in each gel, and 140 protein spots also were identified. Among the identified proteins, there were seven over-expressed proteins in stomach cancer tissue: NSP3, transgelin, prohibitin, heat shock protein (hsp) 27 and variant, protein disulfide isomerase A3, unnamed protein product and glucose regulated protein. There were also seven under-expressed proteins in stomach cancer: Apolipoprotein A-1, p20, nucleoside diphosphate isomerase A, alpha 1 antitrypsin, desmin, serum albumin and serotransferrin.
Development and Evaluation of Test Methods to Evaluate Water Damage and Effectiveness of Antistripping Agents (2005)

Moisture damage in hot-mix asphalt (HMA) mixtures occurs when water can infiltrate the pavement system. Pore water in mixtures can cause premature failure of HMA pavements, primarily through loss of adhesion between the asphalt binder and the aggregates or the loss of cohesion in the asphalt binder. Loss of adhesion can lead to stripping and raveling. The stripping of asphalt films from the surface of aggregate particles may occur as a result of poor adhesion of the asphalt to aggregate surfaces or displacement of the asphalt films by water which is attracted by hydrophilic aggregates, the latter being considered as true stripping. Siliceous aggregates are generally considered as the source of the problem since forms of crystalline quartz often inhibit the development of good adhesion, and in some cases cannot be coated with asphalt. Liquid antistrip agents are often added to asphalt cements to promote adhesion and prevent stripping. Lime treatment of aggregate prior to production of HMA is considered as an alternative measure in the prevention of stripping. Currently available laboratory testing procedures all evaluate the effects of water damage in the laboratory by measuring the relative change of a single parameter before and after conditioning (i.e., tensile strength ratio, resilient modulus ratio). These parameters do not distinguish between the different mechanisms present in a conditioned mixture, including the identification of the effects of pore water versus actual moisture damage. The current Superpave mixture design specification uses the AASHTO T-283 moisture susceptibility test for determining moisture sensitive mixtures. Most state agencies use AASHTO T-283 test, although there have been questions by the community at large about the accuracy of the test. Frequent false positives and/or negatives have been reported, leading to the initiation of this current study. This report developed test methods and criteria needed to relate mixture characteristics with the potential severity of moisture damage. The results showed that no single mixture property can be used to consistently monitor the effects of moisture damage in mixtures. Therefore, a fundamental theoretical framework for the evaluation of moisture damage in mixtures was developed, along with associated specification parameters. The new theoretical framework is based on the Florida HMA fracture model, developed at the University of Florida. A new moisture conditioning procedure using cyclic pore pressures was also developed based on fundamental considerations. The new conditioning and evaluation methods were tested on mixtures of varying aggregate types and gradations. The results presented show that the Florida HMA fracture mechanics model provides highly consistent evaluation of the level of moisture damage in mixtures. These test methods are also shown to be capable of evaluating the effectiveness of antistripping agents, considered to enhance the adhesion of asphalt binders to aggregate surfaces.
Development of Rapid Mercury Assays. Synthesis of Sulfur- and Mercury-Containing Conjugates (1995)

We have devised rapid analyses for mercury exploiting the high affinity of dithiocarbamate chelators for the mercuric ion. Our first assay is based on a sandwich chelate formed by a ligand supported on the well of an ELISA plate, Hg2+ ion of the investigated sample, and another ligand bound to a reporter enzyme. The second assay utilizes competitive binding of the analyte Hg2+ ions versus an organomercury conjugate to a chelating conjugate. Low ppb sensitivity and high selectivity for Hg2+ ions have been achieved in our pilot studies.
Query Interactions in Database Systems (2013)

I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. ii The typical workload in a database system consists of a mix of multiple queries of different types, running concurrently and interacting with each other. The same query may have different performance in different mixes. Hence, optimizing performance requires reasoning about query mixes and their interactions, rather than considering individual queries or query types. In this dissertation, we demonstrate how queries affect each other when they are executing concurrently in different mixes. We show the significant impact that query interactions can have on the end-to-end workload performance. A major hurdle in the understanding of query interactions in database systems is that there is a large spectrum of possible causes of interactions. For example, query interactions can happen because of any of the resource-related, data-related or configuration-related
Instantaneous ego-motion estimation using Doppler radar (2013)

The growing use of Doppler radars in the automotive field and the constantly increasing measurement accuracy open new possibilities for estimating the motion of the ego-vehicle. The following paper presents a robust and self-contained algorithm to instantly determine the velocity and yaw rate of the ego-vehicle. The algorithm is based on the received reflections (targets) of a single measurement cycle. It analyzes the distribution of their radial velocities over the azimuth angle. The algorithm does not require any preprocessing steps such as clustering or clutter suppression. Storage of history and data association is avoided. As an additional benefit, all targets are instantly labeled as stationary or non-stationary.
Catalytic decomposition of nitric oxide over copper(II)-exchanged, Y-type zeolites (1981)

The catalytic decomposition of NO has been investigated over copper(II)-exchanged Y-type zeolites (CuNaY) at 573–823 K in a flow reactor. CuNaY exhibited an appreciable activity above 723 K and was not poisoned by either oxygen or water vapour. In the presence of the CuNaY catalyst (69% exchanged) using a contact time of 11 g(catalyst) s cm–3(gas), the extent of elimination of NO (4 vol%) in diluent helium was found to attain ca. 100% at 773 K. Below 673 K, the catalytic activity slowly declined with increasing reaction time and was restored to its original state upon heating the catalyst above 723 K. This phenomenon results from the accumulation and desorption of oxygen released from the decomposed NO. The influence of the CuII ion-exchange level on the catalytic activity has been examined and it was concluded that the active sites for the reaction are the CuII ions located at sites SII and SIII. Upon adsorption of NO at 273 K on CuNaY substantial amounts of N2O, N2 and O2, as well as NO, appear in the temperature-programmed desorption chromatogram. Based on the results of thermal desorption of various adsorbates and the temperature-dependence of N2O decomposition, two reaction paths of NO are proposed, including direct decomposition to N2 and O2 and consecutive decomposition through N2O as an intermediate.
PDA Virus Filter Task Force update. (2004)

The PDA Virus Filter Task Force has made significant progress in producing a method that will standardize the nomenclature for virus-removal filters that remove large viruses. A method for preparation of the model bacteriophage, PR 772, has also been produced and will shortly undergo a feasibility study. A technical report on the use of virus removal filters is also being prepared.
Sortilin is upregulated during osteoblastic differentiation of mesenchymal stem cells and promotes extracellular matrix mineralization (2002)

Osteoblasts and adipocytes are derived from a common precursor in bone marrow, the mesenchymal stem cell (MSC). Factors driving human MSCs (hMSCs) to differentiate down the two lineages play important roles in determining bone density because it has been shown that bone volume loss associated with osteoporosis and aging is accompanied by reduced osteoblastic bone formation and increased marrow adipose tissue. The genes upregulated in hMSCs during osteogenic differentiation were screened using cDNA microarrays and were semi-quantitated by real-time RT-PCR. One of the genes identified was sortilin, which was upregulated one day after osteogenic induction and remained upregulated for a week. The overexpression of sortilin in hMSCs using an adenovirus vector resulted in the acceleration of mineralization during osteogenic differentiation without affecting alkaline phosphatase activity. Lipoprotein lipase (LPL), produced by adipocytes, is bound by sortilin, which may mediate its endocytosis. By adding LPL to osteogenic induction medium, osteoblastic mineralization was inhibited in a dose-dependent manner. Interestingly, sortilin overexpression abolished the LPL-mediated suppression of osteogenic differentiation. hMSCs exist in marrow where LPL-producing adipose cells are abundant and where osteogenesis is negatively regulated by LPL. Sortilin has a counter effect of promoting osteogenesis by acting as a scavenger of LPL.
Nonnatural Phospholipids: Probing Nature's Modular Platform (2009)

Life as we know it would not be possible without a cellular membrane, without a separation between two compartments. This plasma membrane, however, remains a difficult object to study directly. The synthesis of nonnatural phospholipids thus provides valuable probes for experiments at the membrane-level and integrates organic chemistry with basic biophysics and biology. A few of the concepts are highlighted in this brief overview.
Controlled synthesis of Co3O4 spinel with Co(acac)3 as precursor (2012)

Cobalt(III) acetylacetonate (Co(acac)3) was used as a precursor to grow pure Co3O4 with pulsed-spray evaporation chemical vapor deposition (PSE-CVD). The effect of solvent and substrate temperature on the growth kinetics and morphology of the films was investigated. The obtained spinel exhibited good catalytic performance.
Lack of evidence for mutation to erythromycin resistance in clinical strains of Staphylococcus aureus. (1977)

The properties of 100 erythromycin resistant strains of Staphylococcus aureus obtained from clinical material have been compared with the properties of mutants selected in vitro for resistance to erythromycin. The properties, including inducibility of the resistance and cross-resistance to spiramycin and lincomycin, of the two groups of isolates were always different. The risk that staphylococci will mutate to erythromycin resistance during therapy with this antibiotic is remote.
Neural Architecture Search on ImageNet in Four GPU Hours: A Theoretically Inspired Perspective (2021)

Neural Architecture Search (NAS) has been explosively studied to automate the discovery of top-performer neural networks. Current works require heavy training of supernet or intensive architecture evaluations, thus suffering from heavy resource consumption and often incurring search bias due to truncated training or approximations. Can we select the best neural architectures without involving any training and eliminate a drastic portion of the search cost? We provide an affirmative answer, by proposing a novel framework called training-free neural architecture search (TE-NAS). TE-NAS ranks architectures by analyzing the spectrum of the neural tangent kernel (NTK) and the number of linear regions in the input space. Both are motivated by recent theory advances in deep networks and can be computed without any training and any label. We show that: (1) these two measurements imply the trainability and expressivity of a neural network; (2) they strongly correlate with the network's test accuracy. Further on, we design a pruning-based NAS mechanism to achieve a more flexible and superior trade-off between the trainability and expressivity during the search. In NAS-Bench-201 and DARTS search spaces, TE-NAS completes high-quality search but only costs 0.5 and 4 GPU hours with one 1080Ti on CIFAR-10 and ImageNet, respectively. We hope our work inspires more attempts in bridging the theoretical findings of deep networks and practical impacts in real NAS applications. Code is available at: https://github.com/VITA-Group/TENAS.
Asymmetric magnetic <scp>NOT</scp> gate and shift registers for high density data storage (2010)

We have developed an asymmetric ferromagnetic NOT gate and shift register optimized on a square grid. This gives rise to a two-dimensional storage scheme built up by tessellating an elementary data unit, which is scalable down to very narrow wire widths. The areal footprint of each storage unit is 15F2, where F is the minimum feature size. We experimentally demonstrate NOT operations across a chain of three gates made from Permalloy with F=60 nm, and present a functional 15-gate, multichannel shift register with electrical injection, and optical readout.
Reducing mass peak instability caused by the phase changes of RF and AC signals in a rectilinear ion-trap analyzer (2017)

For an ion trap with resonance ejection, peak intensity and peak position of the acquired mass spectra are affected by the phase difference between the radio frequency (RF) and auxiliary alternating current (AC) potentials. To ensure measurement stability, RF and AC phase-locking is commonly used in commercial ion trap mass spectrometers. In this study, a compact electronic control system was developed to accurately regulate the RF and AC phases and was employed in a photoionization rectilinear ion trap (RIT) mass spectrometer. We found that the phase-locking method was defective in multicomponent analysis because the optimal RF and AC phase difference was usually different for different m/z peaks. After studying and characterizing the relationship between the peaks and the RF and AC phases, a correction method based on data processing was used to improve the peaks' stability and accuracy. The results show that the fluctuations of both peak intensity and peak position were significantly reduced and that the instrument presented satisfying reproducibility and quantitative ability.
Statistical transformations of frontal models for non-frontal face verification (2005)

In the framework of a face verification system using local features and a Gaussian mixture model based classifier, we address the problem of non-frontal face verification (when only a single (frontal) training image is available) by extending each client's frontal face model with artificially synthesized models for non-frontal views. Furthermore, we propose the maximum likelihood shift (MLS) synthesis technique and compare its performance against a maximum likelihood linear regression (MLLR) based technique (originally developed for adapting speech recognition systems) and the recently proposed "difference between two universal background models" (UBMdiff) technique. All techniques rely on prior information and learn how a generic face model for the frontal view is related to generic models at non-frontal views. Experiments on the FERET database suggest that that the proposed MLS technique is more suitable than MLLR (due to a lower number of free parameters) and UBMdiff (due to lack of heuristics). The results further suggest that extending frontal models considerably reduces errors.
Anti-inflammatory properties of histone deacetylase inhibitors (2012)

Treatment with SAHA attenuates hypoxia-HIF-1α-inflammatory pathway in macrophages and suppresses hypoxia-induced release of proinflammatory NO and TNF-α. SAHA also causes an early increase in cellular PHD2, which provides, at least in part, a new explanation for the decrease in the HIF-1α protein levels.
Functional assessment of a B cell defect in patients with selective IgA deficiency. (1979)

The cellular basis of selective IgA deficiency was investigated by examining the terminal differentiation of B lymphocytes co-cultured with varying ratios of T lymphocytes in the presence of pokeweed mitogen. Eight patients were studied who had serum IgA concentrations <0·05 mg/ml, salivary IgA <0·01 mg/ml, and between 0·8 and 4% lymphocytes with surface IgA markers. Peripheral blood lymphocytes from patients and normal donors were separated into B cell (non T cell) and T cell fractions by E-rosetting. Microcultures were established at eleven B cell to T cell ratios from 100% B cells to 100% T cells. After 7 days, immunoglobulin in the supernatant fluid was measured by radioimmunoassay. Cultures containing patients' B cells and either autologous or allogeneic T cells produced very low or undetectable amounts of IgA. However, cultures from six out of eight patients contained cells with intracytoplasmic IgA. Secretion of IgM by the patients' B cells was identical to that of normal donors. Surprisingly, IgG production by patients' B cells was less than that produced by normal B cells especially in the mid-range ratios of the microcultures. Production of IgA, IgG and IgM by normal B cells from peripheral blood or tonsils was very similar in the presence of normal T cells or patients' T cells. In cultures containing optimal ratios of normal B cells, the patients' T cells not only did not suppress IgA production but also gave normal help for IgA production. It was concluded, on the basis of these studies, that a defect in patients with selective IgA deficiency was the functional inability of their B cells to produce normal amounts of IgA in vitro even when provided with normal allogeneic T cell help.
Stereoselectivity of electrophile-promoted cyclizations of .gamma.-hydroxyalkenes. An investigation of carbohydrate-derived and model substrates (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselectivity of electrophile-promoted cyclizations of .gamma.-hydroxyalkenes. An investigation of carbohydrate-derived and model substratesAllen B. Reitz, Samuel O. Nortey, Bruce E. Maryanoff, Dennis Liotta, and Robert Monahan IIICite this: J. Org. Chem. 1987, 52, 19, 4191–4202Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://pubs.acs.org/doi/10.1021/jo00228a009https://doi.org/10.1021/jo00228a009research-articleACS PublicationsRequest reuse permissionsArticle Views1001Altmetric-Citations83LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparison of the gold standard of hemoglobin measurement with the clinical standard (<scp>BGA</scp>) and noninvasive hemoglobin measurement (SpHb) in small children: a prospective diagnostic observational study (2015)

Noninvasive measurement of hemoglobin agrees more with the reference method than the measurement of hemoglobin using a blood gas analyzer. However, both methods can show clinically relevant differences from the reference method (ClinicalTrials.gov: NCT01693016).
The evolution of DRAM technology towards WSI (2002)

Issues connected with the evolution of dynamic random-access memory (DRAM) technology towards wafer scale integration (WSI) are examined. It is pointed out that as one moves towards submicron technologies, fundamental physical, electrical, and processing limits are being encountered, and it is becoming clear that this trend cannot continue. This phenomenon is most clearly demonstrated by the development of DRAM technology. The costs to develop new fabrication lines are escalating to levels that require funding investments approaching national rather that corporate budgets. It is concluded that it is these factors which make WSI and related high-density interconnect technologies an inevitability if demands for higher levels of circuit integration are to continue to be satisfied into the nineties and beyond.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
[Evaluation of IGF-1 concentration in serum and synovial fluid in women with different type coxarthrosis]. (2005)

Osteoarthritis is the greatest problem of aging population. It concerns particularly women over 65 years of age, in considerable degree limiting their locomotion activity. In recent years many different opinions on pathogenesis of osteoarthritis were presented, among them on the role of some growth factors like IGF-1 and TGF-beta playing an anabolic role in cartilage metabolism. The aim of our study was to compare the concentration of IGF-1 in clinically healthy women and women with coxarthrosis and to evaluate the association between IGF-1 in the serum and synovial fluid in relation to disease etiology. We found that in coxarthrosis of either idiopathic, necrotic or dysplastic etiology serum IGF-1 level was significantly lower than in control women (84.4; 76.1; 86.7 vs. 147.7 microg/ml). Concentration of IGF-1 in different groups of patients was similar or lower in synovial fluid than in the serum. Consistently decreased IGF-1 was found in synovial fluid (42.3 microg/ml) of patients with coxarthosis of necrotic origin. Our results suggest that low IGF-1 values, especially in synovial fluid, are in association with type of osteoarthritic changes within the joint, independently on age.