gebhart/patrepeval huggingface dataset:
Shear horizontal guided wave modes to infer the shear stiffness of adhesive bond layers (2010)

This paper presents a non-destructive, ultrasonic technique to evaluate the quality of bonds between substrates. Shear-horizontally polarized (SH) wave modes are investigated to infer the shear stiffness of bonds, which is necessarily linked to the shear resistance that is a critical parameter for bonded structures. Numerical simulations are run for selecting the most appropriate SH wave modes, i.e., with higher sensitivity to the bond than to other components, and experiments are made for generating-detecting pre-selected SH wave modes and for measuring their phase velocities. An inverse problem is finally solved, consisting of the evaluation of the shear stiffness modulus of a bond layer at different curing times between a metallic plate and a composite patch, such assembly being investigated in the context of repair of aeronautical structures.
Transamidation of gluten proteins during the bread-making process of wheat flour to produce breads with less immunoreactive gluten (2014)

Due to an increasing incidence of celiac disease (CD) and other gluten-related disorders, different gluten-free breads have been developed using starches and additives as a substitute for gluten. Thus, patients miss not only the taste and aroma of wheat bread but also risk their sensitive intestines. Therefore, modifying gluten to avoid an immune response in CD and its application to baking is in progress. The aim of the study was to enzymatically modify gluten on wheat flour, during bread-making avoiding the use of additives, to reduce immunoreactivity, preserving its properties. Microbial transglutaminase (mTG) or chymotrypsin (ChT) was used to bind lysine or valine to gluten proteins in a model system. The best conditions were directly applied to wheat flour for bread-making with and without punching at 45 min. Subsequently, the rheological properties of the doughs, specific volume of the loaves, immunoreactive gluten content and modification of the extracted proteins were evaluated. ChT-treated breads presented a better appearance with a more homogeneous crumb, higher specific volume values (3.34-4.25 cm(3) g(-1)) and higher reactive gluten reduction (up to 71%) than the mTG-treated ones (1.23-2.66 cm(3) g(-1)) with only a 42% reactive gluten reduction. Thus, transpeptidation during bread-making is a promising technology, although it is necessary to improve the modification process to obtain the reactive gluten reduction required in breads for the treatment of CD patients and other gluten-related disorders.
Optimization of Value of Aerodrome Forecasts (2003)

Prediction of short-term variations of vital boundary layer conditions at airports, such as visibility and cloud base, is important to the safe and economic operation of airlines. Results of an experiment involving groups of forecasters at three different locations across Australia are presented. The forecasters were asked to indicate their degree of confidence that weather at the airport would be below "minimums" that would require aircraft to carry adequate fuel to proceed to an alternate destination should they not be able to land. The results of the trial are shown to closely obey a Gaussian model as used in signal detection theory (SDT). The data are fitted to an accuracy-value model developed by Mason. The paper demonstrates the ability of forecasters to provide reasonably reliable probability forecasts of significant events at airports. The potential value in reliable estimation of the probability of low visibility and cloud base at aerodromes is estimated by using cost parameters for two actual examples of flights into Melbourne and Townsville, Australia.
Ibsen and Germany (1964)

This thesis is not available on this repository until the author agrees to make it public. If you are the author of this thesis and would like to make your work openly available, please contact us: thesis@repository.cam.ac.uk.
Stimulated-emission cross section at 1064 and 1342 nm in Nd : YVO4 (1977)

The stimulated-emission cross sections at 1064 (4F3/2→4I11/2) and 1342 nm (4F3/2→4I13/2) in Nb : YVO4 were determined by measurement of laser thresholds as a function of output mirror reflectivity. Small samples of Nd : YVO4 and Nd : YAG were end pumped at room temperature with a cw 514.5-nm argon ion laser in an almost identical geometrical arrangement which permitted comparative values to be obtained. Assuming that the pumping quantum efficiency of Nd : YVO is similar to that of Nd : YAG, the stimulated-emission cross sections obtained for the 1064- and 1342-nm transitions were respectively 12×10−19 and 6.0×10−19 cm2.
Support for Drivers via Just-In-Time Predictive Control and Fault Detection Based on a Nearest Neighbor Method during Braking to Stop Trains (2006)

It is important to prevent commuter trains overrunning which are caused by human errors. Although skillful drivers can robustly withstand drastic changes to situations, they may make a mistake. In this paper, we focus on a braking control problem in which the task of the human operator is to make the train stop exactly at a given position. We propose a support system for the human operator, which applies so-called Just-In-Time modeling to predictive control. Moreover, we propose a human-machine interface system which displays the level how far the current manipulation apart from the usual ones by using an input-output database. The effectiveness of the proposed method is demonstrated by simulations of a braking system on trains.
Measurement of Additional Skin Resulting From Perforation Damage (1991)

Abstract Single shot laboratory flow tests were performed on perforated Berea and Gold sandstone cores to determine the additional skin caused by the presence of a perforation damage zone. A variety of underbalances, stresses and wellbore volumes were used. Whole core diametral and axial permeabilities were measured for each core tested. Cores were then perforated under simulated downhole conditions, and radial flow tests were conducted to determine the skin due to the perforation damage zone. Because these measurements gave no information on the distribution of permeability damage, further experiments were carried out using a radial flow permeameter to directly measure the permeability distribution. The radial flow permeameter confirmed the presence of a low permeability region around, but not always adjacent to, the perforation tunnel. Permeability damage at the outside of the cores due to the coring process was also determined. Although one set of experiments shot under identical conditions, at a low underbalance, showed a degree of randomness in the results, the following observations could be made: 1) For the conditions tested, there is no apparent stress effect on the perforation damage skin, 2) The size of accumulator attached to the wellbore affected the resulting skins, and 3) Results of single shot experiments should be used with extreme care.
Framework for mining event correlations and time lags in large event sequences (2017)

Event correlation is the task of detecting dependencies between events in event sequences, e.g., for predictive maintenance based on log-files. In this work, a new data-driven, generic framework for event correlation is presented. First, we use a fast preliminary test statistic to determine candidate event type pairs. Next, the precise distribution of the time lag between those pairs is calculated. For this purpose, a new efficient iterative method is developed that aligns two event sequences and finds the optimal event assignments. In our experiments, the proposed method is orders of magnitude faster than state-of-the-art methods but always yields similar (or even better) results.
Three-Dimensional Electron Microscopy of Macromolecular Assemblies (2006)

In this book, the mathematical principles and working methods of single-particle reconstruction are described; a method designed to retrieve three-dimensional structural information from electron micrographs showing thousands of “copies” of biological molecules trapped in a thin layer of ice. This technique is uniquely suited to obtain three-dimensional images of molecular machines in different functional states, as it dispenses with the need for crystals. The book starts with an introduction of image formation in the electron microscope, which includes the definition of the contrast transfer function. Next, averaging techniques and tools for image alignment, multivariate data analysis, and classification are described. An introduction into the mathematical principles underlying reconstruction of an object from its projections is followed by detailed accounts on how projection angles are determined, and how reconstruction is done in practice. The book concludes with a chapter on interpretation of density maps reconstructed, including methods for segmentation as well as fitting and docking of atomic coordinates.
Transcription Factors and Human Disease (1998)

Part I: Transcriptional Regulation 1. Gene Expression and Transcriptional Regulation 2. Cis-acting Transcriptional Regulatory Elements 3. Trans-acting Factors Part II: Transcriptional Pathophysiology 4. Mutations in Cis-acting Transcriptional Regulatory Elements 5. Mutations in Genes Encoding Transcription Factors: The Nuclear Receptor Superfamily 6. Other Zinc-Finger Proteins: WT1 and GL13 7. PAX Proteins 8. bHLH Proteins 9. Homeodomain Proteins 10. HMG Domain Proteins 11. POU Domain Proteins 12. Other Transcriptional Factor Families 13. Co-activators 14. General Transcription Factors 15. Somatic Cell Genetic Disease: Cancer 16. Epidenetic Disease: Teratogenesis
Signal-to-noise enhancement of NMR spectra of solids using multiple-pulse spin-echo experiments (2005)

Three multiple-pulse spin-echo experiments that have been used to enhance the sensitivity of broad powder patterns obtained from NMR spectra of spin-1/2 and half-integer quadrupolar nuclei in polycrystalline solids are examined. Specifically, the Carr-Purcell Meiboom-Gill (CPMG), the Mansfield-Waugh (MW-4), and a modified version of the CPMG experiment (modified-CPMG) are described and compared. Use of these pulse sequences results in transforming the broad powder lineshapes into a series of narrow spikelets whose overall envelope mimics that obtained from the normal Hahn-echo experiment. The CPMG and modified-CPMG methods can result in a considerable saving in experiment time and are particularly powerful in studying the central transition of half-integer spin quadrupolar nuclei. Artifacts generated by the MW-4 sequence or caused by imperfections in the π pulses in the CPMG sequences are explained using a product operator analysis. © 2005 Wiley Periodicals, Inc. Concepts Magn Reson Part A 26A: 62–77, 2005
Criteria for absorber's reflectivity lined in semi-anechoic chambers using ray-tracing technique (2002)

Semi-anechoic chambers are used for EMC measurement from 30 MHz to 1000 MHz. Criteria for absorber's reflectivity lined in semi-anechoic chambers are discussed based on a ray-tracing analysis. The absorber's reflectivity of -15 dB and -20 dB for normal incidence is sufficient to satisfy a standard in 3 m and 10 m measurement methods, respectively. The dimensions of the chamber can be reduced to L=8 m, W=6 m and H=5 m for the 3 m method and to L=18 m, W=13 m and H=7 m for the 10 m method.
Impact Analysis of System and Network Attacks (2021)

Systems and networks have been under attack from the time the Internet first came into existence. There is always some uncertainty associated with the impact of the new attacks. Compared to the problem of attack detection, analysis of attack impact has received very little attention. Generalize and forecasting the kind of attack that will hit systems in future is not possible. However, it is possible to predict the behavior of a new attack and, thereby, the impact of the attack. This thesis proposes a method for predicting the impact of a new attack on systems and networks as well as the severity of the impact of the new attack. The prediction is based on the assumption that a future attack will be similar to already existing attacks. The severity of the attack depends on a few specific system/network parameters identified in this thesis. The cumulative effect of an attack is a summation of the behavior of these identified parameters during the attack. The suggested method is based on simulating a selected number of existing attacks, collecting the results of the impact of these attacks, and using them along with attack graphs to automatically detect the impact of a new attack. A formula is proposed for calculating the impact severity percentage, which is calculated as a percentage value of the impact of the known attack. This value will help identify critical points that need special care to ensure the readiness of a network or system to withstand an attack.
SHARP control (2009)

Shared resources in a chip multiprocessors (CMPs) pose unique challenges to the seamless adoption of CMPs in virtualization environments and high performance computing systems. While sharing resources like on-chip last level cache is generally beneficial due to increased resource utilization, lack of control over management of these resources can lead to loss of determinism, faded performance isolation, and an overall lack of the notion of Quality of Service (QoS) provided to individual applications. This has direct ramifications on adhering to service level agreements in environments involving consolidation of multiple heterogeneous workloads. Although providing QoS in presence of shared resources has been addressed in the literature, it has been commonly observed that reservation of resources for QoS leads to under-utilization of resources.
System Considerations for Hardware Parameters in a 60 GHz WLAN (2000)

In the framework of HFE (High-Frequency Electronics) programme, funded by SSF (Foundation for Strategic Research), an activity on microelectronics for millimeter wave applications has started. As a result from this work, a broadband wireless 60 GHz transceiver demonstrator for WLAN:s (Wireless Local Area Network) will be developed. It is therefore important to identify the relevant technical limitations. Intermediate goals are to set up a possible 60 GHz wireless communication model and to study the influence of electronic MMIC (Monolithic Microwave Integrated Circuit) characteristics on the system performance. In this paper, we analyze a possible set-up to modulate and demodulate digital signals via a given analog front-end transceiver.
Electroless nickel bumping of aluminum bondpads. I. Surface pretreatment and activation (2002)

Electroless nickel bumping of aluminum (Al) bond-pads followed by solder paste printing is seen as one of the lowest cost routes for the bumping of wafers prior to flip-chip assembly. However, the electroless nickel bumping of Al bondpads is not straightforward and a number of activation steps are necessary to enable the nickel deposit to form a strong, electrically conductive bond with the Al. For the electroless nickel coating of mechanical components made of aluminum, a zincate activation process has been used for many years; however, extension of these techniques to semiconductor wafers requires careful control over these pretreatments to avoid damage to the very thin bondpads. This paper reports a number of experiments designed to characterize the activation of Al bondpads to electroless nickel plating, focusing on the effects of solution exposure time and bondpad composition. In addition, the results are discussed in the context of other studies presented in the literature to provide an understanding of the mechanism of the zincate activation process applied to Al bondpads.
Gastrointestinal, Hepatobiliary, and Nutritional Physiology (1996)

Part I Gastrointestinal physiology: regulation and integration of gut functions gastrointestinal motility and neurophysiology gastric physiology exocrine pancreatic physiology intestinal water and electrolyte transport. Part II Nutritional physiology: digestion and absorption of carbohydrates and proteins digestion and absorption of dietary triglycerides digestion and absorption of other dietary lipids absorption of water-soluble vitamins and minerals. Part III Hepatobiliary physiology: liver physiology i - structure functional assessment, and blood flow liver physiology ii - the role of the liver in protein synthesis and nutrient metabolism liver physiology iii - the role of the liver in biotransformation, elimination, and bile acid metabolism.
Vascular endothelial growth factor does not improve liver regeneration and survival after 90% subtotal liver resection (2007)

Aim: Vascular endothelial growth factor (VEGF) has been shown to stimulate liver regeneration after 70% partial hepatectomy (PH). It is unclear, however, whether exogenous administration of VEGF can also be used to improve liver regeneration and survival after 90% subtotal liver resection. The aim of this study was to determine the effect of exogenous and endogenous VEGF after 90% subtotal hepatectomy (SH). Methods: Rats were subjected to 90% SH and treated with VEGF, anti‐VEGF or NaCl. Postoperatively (3 h – 5 days) liver body weight ratio (LBR), hepatocyte proliferation and biochemical markers were assessed. ELISA was performed to measure protein levels for VEGF. Gene expression was determined by customized cDNA arrays and quantitative RT‐PCR. Results: Administration of VEGF did not enhance LBR or hepatic proliferation, or reduce the serum parameters. VEGF levels were the highest in VEGF‐treated animals. The overall survival after 90% SH reached 78% in VEGF‐treated animals, but did not differ significantly from that of anti‐VEGF or NaCl‐treated animals (74% and 75%, respectively). Gene expression analysis showed a modulation of anti‐apoptotic and cell cycle control genes that was independent of VEGF. Conclusions: In contrast to PH, liver regeneration and survival after SH cannot be modulated by VEGF. This indicates that the relevant mechanisms that stimulate liver regeneration after hepatectomy at least partially depend upon the extent of liver resection.
Antarctica: the effect of high latitude heterochroneity on the origin of the Australian marsupials (1989)

Abstract The record of the Antarctic marine fauna during the Paleogene indicates the occurrence of taxa in high latitude regions (>60°) before these same taxa are known in midto low latitudes. It has been hypothesized that high latitude regions serve both as ‘holding tanks’ for taxa and as regions in which novel adaptations leading to new lineages within a taxon can arise. These features of high latitude regions appear to have had a major impact on the origin of the Australian marsupial fauna. The australidelphian marsupial clade (all Australian marsupials plus South American microbiotheriids) and the ameridelphian marsupial clade (all South American marsupials except microbiotheriids) diverged in the Late Cretaceous. The South American marsupial radiation occurred in mid- to low latitude regions during the Late Cretaceous to early Paleocene. The Australian marsupial radiation probably did not occur until the medial or late Eocene. If accurate, this represents a time differential of 20 to 25 Ma between the two marsupial radiations. The heterochroneity of the marsupial radiations results from the fact that during the Late Cretaceous to Eocene, Australia resided in a high latitude region, the cool temperate Weddellian Biogeographical Province. The radiation of Australian marsupials only reaches a level of taxonomic diversity comparable to that in South America after the continent drifted northward into lower latitudes and habitat diversity increased. This is deduced from changes in floral diversity and the projected timing of the diprotodontian divergences based on DNA hybridization data.
Fetal antigens shared as transplantation rejection antigens on chemically induced mouse and hamster sarcomas. (1980)

We have previously reported that two chemically induced sarcomas of BALB/c mice (MCA-1315 and -1321) contained common transplantation antigens which could be detected by immunization of normal BALB/c mice with irradiated tumor cells of each line. This cross-protection could not be detected in animals surgically cured of these tumor lines and challenged with a high dose of tumor cells, but it was detectable in similar animals challenged with low doses of homologous tumor cells. In this report, we demonstrate that these chemically induced tumor lines carry fetal antigens which are recognized by cytotoxic or inhibitory mouse BALB/c maternal lymphocytes sensitized during pregnancy to mouse fetal antigen. A similar fetal antigen determinant was observed on two chemically induced sarcomas of hamster which were likewise recognized by hamster maternal lymphocytes derived from 10-day pregnant donors. The time course of appearance and disappearance of spleen or exudate cells from pregnant mice capable of protecting BALB/c mice against challenge with these fetal antigen-bearing 3-methylcholanthrene-induced tumor target cells was determined. Protective lymphocytes were not detected in primiparous mice two days prior to parturition and appeared after Day 10 in pregnancy. Among animals experiencing multiple pregnancies, low but reproducible levels of protector lymphocytes could be detected by Day 8 to 9, and protective lymphocytes persisted to parturition in these animals. Correlations of these results with previous reports from this laboratory concerning the expression of fetal antigens in the membranes of embryonic and fetal cells of hamsters and mice are discussed. These data establish that common antigens shared as transplantation rejection antigens between chemically induced sarcomas of mice and hamsters are of fetal or embryonic origin.
Basalt leaching with orthophosphoric acid (2009)

Basalt leaching with orthophosphoric acid is studied by the method of isothermal dissolution. The total degree of dissolution of basalt and degrees of extraction into solution of separate elements as a function of temperature (20, 100°C), acid concentration (5–40%), and liquid-to-solid ratio are determined. Through the control of leaching conditions, it is possible to vary the coefficient of acidity of the basalt charge, decreasing the content of separate components. The possibility, in principle, of using this process for the optimization of charge composition in the manufacture of basalt-fiber materials and cast stone products is shown.
Preclinical and clinical data with bispecific antibodies recruiting myeloid effector cells for tumor therapy (2001)

Bispecific antibodies constitute a novel approach to improve antibody efficacy. In vitro, constructs to recruit myeloid effector cells have been extensively investigated, and first animal data in human Fc receptor transgenic mice confirmed their promising therapeutic potential. Clinical experience with these constructs demonstrated acceptable toxicity, and support therapeutic efficacy in subgroups of patients. However, limited availability, unacceptable immunogenicity, and unfavorable pharmacokinetics of bispecific compared to conventional antibodies often hampered clinical studies. As solutions to these problems are available today, bispecific antibodies hold promise to improve therapeutic efficacy of antibody-based approaches in the near future.