gebhart/patrepeval huggingface dataset:
A SIMPLE SYNTHESIS OF α,β-UNSATURATED ALDEHYDES BY THE REACTION OF VINYLSILANES WITH DICHLOROMETHYL METHYL ETHER PROMOTED BY TITANIUM(IV) CHLORIDE. APPLICATION TO THE SYNTHESIS OF ETHYL 12-OXO-10(<i>E</i>)-DODECENOATE AND NUCIFERAL (1978)

Abstract 1,2-Disubstituted vinyltrimethylsilanes (1) readily underwent formylation with replacement of the silyl group when treated with dichloromethyl methyl ether and titanium(IV) chloride. This reaction provides a simple procedure for the selective preparation of (E)-2-alkenals (2) and was conveniently applied to the synthesis of ethyl 12-oxo-10(E)-dodecenoate and nuciferal.
Detection of Spatiotemporal Asymmetry in Pro Level Soccer Players (2017)

Knudsen, NS and Andersen, TB. Detection of spatiotemporal asymmetry in pro level soccer players. J Strength Cond Res 32(3): 798-804, 2018-Several papers have focused on change of direction (COD) asymmetry investigated through standardized tests, and used this information to provide some spatiotemporal insight during games. The aim of this study was to investigate asymmetry in the reachable areas of the players through actual position data from soccer games. Sixteen professional players from the Danish Superliga participated in this study, but 5 were excluded because of lack of participation throughout the investigated games. The reachable areas of the players were investigated at varying sprint velocities (1-7 m·s) and within varying time intervals (0.5-4 seconds). The analysis found 7 players having spatiotemporal asymmetries in their reachable areas (0.5-3%) and shift of center of reachable area (4-29 cm). Four players (LB, RB, DM, and CF) had spatiotemporal asymmetries that could be attributed to COD and thus physiological asymmetries, whereas 3 players (LCB, LW, and RW) had spatiotemporal asymmetries that might be caused by their position or by use of tactic. This type of asymmetry was named a tactical spatiotemporal asymmetry. Coaches with knowledge about spatiotemporal asymmetries can use these actively in their tactical approach using the players' asymmetries in synergy, using opponents' asymmetries or improving the existing postgame spatiotemporal analyzing tools.
1,1,2,2,9,9,10,10-Octafluoro[2,2]paracyclophane (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,1,2,2,9,9,10,10-Octafluoro[2,2]paracyclophaneSui-Wu. Chow, L. A. Pilato, and W. L. WheelwrightCite this: J. Org. Chem. 1970, 35, 1, 20–22Publication Date (Print):January 1, 1970Publication History Published online1 May 2002Published inissue 1 January 1970https://pubs.acs.org/doi/10.1021/jo00826a005https://doi.org/10.1021/jo00826a005research-articleACS PublicationsRequest reuse permissionsArticle Views310Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Single Nanoparticle Trapping Using a Raman Tweezers Microscope (2002)

We have obtained a Raman spectrum of single nanometer-sized particles (nano-particles) trapped by laser tweezers for the first time. The microscope used in this study is a new version of our Raman tweezers microscope (RTM); it contains an oil-immersed objective lens with high numerical aperture to increase the force of the optical radiation pressure of the near-infrared laser beam to trap single organic and biological nanoparticles and provides sufficient sensitivity for the Raman measurement of the trapped nano-particles. The confocal arrangement in the system completely eliminates the Raman signal of the oil under the objective lens. The RTM provides a Raman spectrum of a single polystyrene latex bead about 40 nm in diameter with an exposure time of 3 s and allows us to determine its molecular species. Furthermore, the RTM enables us to count the number of nanoparticles in the focal spot of the laser beam from the Raman spectra of trapped nanoparticles.
Enhancing Interoperability via Generic Multimedia Syntax Translation (2006)

The Bitstream Binding Language (BBL) is a new technology developed by the authors and being standardized by MPEG, which describes how multimedia content and metadata can be mapped onto streaming formats. This paper describes how BBL can be used to enhance the interoperability of multimedia content by providing a generic mechanism for the translation of content between formats. As new content formats are developed, BBL can be used to describe how to translate the content into a form that existing devices are able to render. This consequently simplifies the adoption of new multimedia content forms because existing devices are able to consume the content even though they do not understand its native format
Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue (2009)

We show for the first time that elimination of dietary leucine produces significant metabolic changes in WAT and BAT. The effect of leucine deprivation on UCP1 expression is a novel and unexpected observation and suggests that the observed increase in energy expenditure may reflect an increase in thermogenesis in BAT. Further investigation will be required to determine the relative contribution of UCP1 upregulation and thermogenesis in BAT to leucine deprivation-stimulated fat loss.
Continuous Insulin Releasing and Blood Sugar Monitoring via Dental Implant Supported Semi-Implanted Device (2016)

As life expectancy prolonged currently, geriatrics become important and therefore it is urgent to improve the life quality throughout the chronic and critical diseases among the elderly above sixty-fifth years old.
Stackably extensible template layer for file system development under Windows NT (Family) (2004)

This paper describes an architecture for stackably extending file functionality under Windows NT (Family) with minimal performance overhead and development cost. File systems often need to evolve and require many changes to support new features. Traditional file system development is difficult because most of the work is done in the kernel - a hostile development environment where progress is slow, debugging is difficult, and simple mistakes can crash systems. Kernel work also requires deep understanding of system internals, resulting in developers spending a lot of time becoming familiar with the system's details. Stackably extensible file systems promise to ease the development of file systems by offering a mechanism for incremental development. The Stackably Extensible Template Layer environment is an NT service-based COM (A. Rofail and Y. Shohoud, Mastering COM and COM+, SYBEX, San Francisco, USA, 2002) (component object model) server that seamlessly integrates with file system filter drivers (stacked modules that can be inserted anywhere in the drivers' calling hierarchy for intercepting file system operations) via the inverted call model supported in the Windows OS architecture and by sharing events between kernel and user mode. Stackably extensible template layer promises to speed file system development by providing an extensible file system interface. This extensibility allows new features to be added incrementally from the user mode.
Schottky metal-GaN interface KOH pretreatment for improved device performance (2010)

The effect of KOH pretreatment for Au/Ni Schottky contacts to GaN is investigated using I-V and x-ray photoemission spectroscopy (XPS) analysis. The molten KOH pretreatment reduces the interface trap density from 1.0×1012 to 2×1011 cm−2 eV−1, improves the on-state performance, and increases the barrier height by 10%. XPS indicates that KOH improves the GaN Schottky diode performance by eliminating an oxide layer between the metal and the semiconductor, increasing the band bending through charge transfer, and improving the GaN stoichiometry at the surface. First principle simulations indicate that the nitrogen antisite and to a minor extent the gallium antisite are also possible constituents of this interfacial layer along with gallium and nitrogen vacancies. These antisite defects can be passivated by KOH.
Measurement of arterial input functions for dynamic susceptibility contrast magnetic resonance imaging using echoplanar images: Comparison of physical simulations with in vivo results (2006)

Measurement of the arterial input bolus shape is essential to the quantification of mean transit time and blood flow with dynamic susceptibility contrast (DSC) MRI. Input functions derived from the echoplanar signal intensity within or near arteries are highly nonlinear, yet such input functions are widely used. We employed a physical model for the echoplanar signal intensity from an artery as a function of contrast agent concentration, artery size, and angle to the magnetic field to test approaches for the measurement of the arterial input function. The simulated results confirmed the strong nonlinearity of signal in the neighborhood of vessels. Of the input function measurement methods considered, the simulations suggested that measurement of signal near but not within a large vessel is most accurate, but mean transit times (MTT) calculated with these input functions are highly sensitive to peak bolus concentration. Input functions determined from voxels demonstrating the shortest first moment overestimated the MTT but the measured MTTs were more robust to changes in peak concentration. Characteristics of the measured in vivo input functions were consistent with the simulations. Our results emphasize the important contribution of input function errors to the uncertainty in MTT and blood flow imaging with DSC MRI.
Investigation of Plasma Charging damage impact on device and gate dielectric reliability in 180nm SOI CMOS RF switch technology (2009)

The impact of charging damage from plasma processes on device and gate dielectric reliability is investigated for MOSFETs fabricated in an SOI CMOS RF Switch technology. Although results from voltage breakdown measurements do not reveal any indication of plasma damage, detrimental antenna effects are observed on the negative bias temperature instability (NBTI) and hot carrier device performance. With regard to NBTI in P-channel SOI MOSFETs in particular, relaxation experiments are carried out under various bias conditions. Recovery effects which are well known for intrinsic NBTI are also observed for the antenna devices, but are found to be reduced relative to that of control devices.
Drying inland seas probably helped kill Australia’s megafauna (2015)

Events some 40,000 to 60,000 years ago marked a critical juncture in the Australian continent’s history. This is when humans first arrived and also the time when many huge beasts, known as megafauna, seem to have disappeared. So what caused their demise: humans, a changing climate, or both? Disciplines Medicine and Health Sciences | Social and Behavioral Sciences Publication Details Cohen, T., Nanson, G., Jansen, J. & Larsen, J. (2015). Drying inland seas probably helped kill Australia’s megafauna. The Conversation, 26 February 1-3. This journal article is available at Research Online: http://ro.uow.edu.au/smhpapers/2846 There's still time to make a tax deductible donation before June 30.
Cross phase modulation measured in optical fibers (1987)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text R. R. Alfano, P. L. Baldeck, F. Raccah, and P. P. Ho, "Cross phase modulation measured in optical fibers," Appl. Opt. 26, 3491-3492 (1987) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
PotentialNet for Molecular Property Prediction (2018)

The arc of drug discovery entails a multiparameter optimization problem spanning vast length scales. The key parameters range from solubility (angstroms) to protein-ligand binding (nanometers) to <i>in vivo</i> toxicity (meters). Through feature learning-instead of feature engineering-deep neural networks promise to outperform both traditional physics-based and knowledge-based machine learning models for predicting molecular properties pertinent to drug discovery. To this end, we present the PotentialNet family of graph convolutions. These models are specifically designed for and achieve state-of-the-art performance for protein-ligand binding affinity. We further validate these deep neural networks by setting new standards of performance in several ligand-based tasks. In parallel, we introduce a new metric, the Regression Enrichment Factor EF<sub>χ</sub> <sup>(R)</sup>, to measure the early enrichment of computational models for chemical data. Finally, we introduce a cross-validation strategy based on structural homology clustering that can more accurately measure model generalizability, which crucially distinguishes the aims of machine learning for drug discovery from standard machine learning tasks.
Optimization of strain gauge for stem measurement using PIC based instrumentation (2011)

Stem measurement is vital since its diameter is related to development of tree as well as water content. Hence, in this study, PIC microcontroller based instrumentation is developed for measuring the changes of linear micrometer that represents the stem diameter changes. Here, the strain gauge is used as a sensor to detect the changes in micrometer for every 1 μm changes. In addition, digital multimeter and digital oscilloscope are used for comparison and validation of the proposed PIC. Results attained proven that the system is capable to measure changes of stem diameter accurately.
A Contingency Model of Response to Performance Feedback (1999)

This study examines patterns of strategic resource allocation decisions and performance feed-back over time for evidence of both incremental adaptation and escalation of commitment. The investment decisions of 20 teams participating in the management simulation MARKSTRAT are examined. The participants were managers enrolled in an executive education program and M.B.A. students. A contingent model of responses to performance feedback is introduced that includes the moderating factors of prior resource commitments, consecutive periods of positive or negative feedback, and performance distance from aspiration. Evidence is found for both incremental adaptation and escalation of commitment. The implication of this study is that responses to performance feedback should be viewed as contingent on a number of factors, such as distance from aspirations and sunk costs associated with a decision.
A self-repairing, supramolecular polymer system: healability as a consequence of donor–acceptor π–π stacking interactions (2009)

A novel supramolecular polymer system, in which the terminal pyrenyl groups of a polyamide intercalate into the chain-folds of a polyimide via electronically-complementary pi-pi stacking, shows both enhanced mechanical properties relative to those of its individual components and facile healing characteristics as a result of the thermoreversibility of non-covalent interactions.
Vascularized Tissue-Engineered Ears (2006)

The authors have shown that transposing a vascular pedicle to a subcutaneously placed silicone block will result in a vascular capsule that can be mobilized and transferred based solely on the pedicle. Although the capsule provides vascularity to the chondrocytes, the cultured cartilage will fill the shape of the silicone mold only if an appropriate carrier such as fibrin glue is used and an external mold is applied.
Synthesis and structure–activity studies of 8α- and 9β-analogues of 14,17-ethanoestradiol (2000)

Synthetic routes to the title compounds are described, commencing with readily available 19-norsteroid precursors. The reaction of 3-methoxy-8α-estra-1,3,5(10),14,16-pentaen-17-yl acetate 3 with phenyl vinyl sulfone at 150 °C proceeded in high yield, but with poor selectivity, to give a mixture of 14α,17-cycloadducts, which underwent convergent functional group modification, to furnish 14α,17α-ethano-8α-estradiol 13. The feasibility of performing similar cycloaddition chemistry on analogous 9β-precursors was demonstrated, but the preferred synthetic route entailed configurational inversion at C-9, of 14α,17α-ethanoestradiol 25, via moderately stereoselective hydrogenation of a 9,11-dehydro intermediate, leading to 14α,17α-ethano-9β-estradiol 32. The estrogen receptor binding affinities of 13 and 32 are reported, and discussed in terms of superimpositional modelling on estradiol.
A choline chloride/DMSO solvent for the direct synthesis of diformylfuran from carbohydrates in the presence of heteropolyacids (2015)

Here we report the one pot conversion of fructose to DFF in the presence of a mixture of choline chloride (ChCl) and DMSO as a solvent and Mo-Keggin heteropolyacids.
Study on ozone treatment of water‐soluble polymers. I. Ozone degradation of polyethylene glycol in water (1976)

Abstract Polyethylene glycol (molecular weight 8000) was degraded by ozone in 1% aqueous solution of pH 12. Chemical oxygen demand of the solution decreased with increasing ozone consumed. Intrinsic viscosity of the solution lowered exponentially as a result of the ozonization. The number of breaks calculated from the viscosity indicated that two molecules of ozone were consumed for one cleavage of the polymer chain. The molecular weight distribution obtained by gel permeation chromatography was very broadened and molecular weight was lower as well, and the polymer chain was found to be cleaved randomly by ozone. The production of formic ester, ethylene glycol, diethylene glycol, triethylene glycol, and hydrogen peroxide was confirmed by IR, NMR, gas chromatography, and chemical analysis. These observations could be accounted for by electrophilic attack of ozone on the ether bond.
Manipulating attention in computer games (2011)

In computer games, a user's attention is focused on the current task, and task-irrelevant details remain unnoticed. This behavior, known as inattentional blindness, is a main problem for the optimal placement of information or advertisements. We propose a guiding principle based on Wolfe's theory of Guided Search, which predicts the saliency of objects during a visual search task. Assuming that computer games elicit visual search tasks frequently, we applied this model in a “reverse” direction: Given a target item (e.g., advertisement) which should be noticed by the user, we choose a frequently searched game item and modify it so that it shares some perceptual features (e.g., color or orientation) with the target item. A memory experiment with 36 participants showed that in an action video game, advertisements were more noticeable to users when this method is applied.
GCIP Is a Tumor Suppressor in Breast Cancer. (2009)

Abstract Background: GCIP protein is a HLH-leucine zipper (HLH-LZ) proteins without basic DNA-binding region, which was identified to be a cyclin D1-binding protein and also was recognized as a human homologue of MAID protein (HHM). Recently, GCIP was found to function as a tumor suppressor in liver and colon tumorigenesis. In this study, we examined in vitro the functional role of GCIP in various breast cancer cell lines.Material and Methods: GCIP-directed siRNA construct was prepared and stable downregulation of GCIP in epithelial-like and nonaggressive/differentiated breast cancer cell line, MCF-7, were selected. In addition, two aggressive/ invasive breast cancer cells (MDA-MB231 and MDA-MB435s) that exhibit low levels of endogenous GCIP expression were transfected with p3x-GCIP-flag, respectively and stable GCIP-re-expressing transfectants were selected. The phalloidin staining cell morphology and functional assays with these stable GCIP downregulating or GCIP re-expressing were performed to characterize the biological effects of GCIP.Results: Stable MCF-7 cells with down-regulated GCIP expression acquired a mesenchymal-like shape and exhibited increased colony formation, migration and invasion capabilities. Furthermore, this was found to be associated with the loss of membrane E-cadherin and increased expression of the mescenchymal marker vimentin. In addition, both the stable MDA-MB231 and MDA-MB435s with GCIP-re-expression acquired an epithelial-like shape and exhibited decreased colony formation, migration and invasion capabilities.Conclusion: our previous study found that decreased expression of GCIP in breast carcinomas compared with normal ductal epithelium (P &lt; 0.001). In this study, we present evidence that GCIP inactivation contributes to the enhanced migratory and invasive capacity of MCF-7 and that GCIP re-expression inhibits a wild range of cellular functions related to the malignant properties of MDA-MB231 and MDA-MB435s, confirming that GCIP is a tumor suppressor in breast cancer. Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 3158.
Subtle Symptoms Associated with Self-Reported Mild Head Injury (1995)

We conducted a survey on the relationship between mild head injury incidence and a variety of psychological and educational symptoms in a sample of 1,345 high school and 2,321 university students. Once figures were adjusted to represent a 50:50 gender ratio, 30% to 37% of subjects reported having experienced a head injury incident, with 12% to 15% of the total group of subjects reporting such an incident with loss of consciousness. We found significant relationships between the incidence of such mild head injury and gender, sleep difficulties, social difficulties, handedness pattern, and diagnoses of attention deficit, depression, and speech, language, and reading disorders.
METAL/METAL ARTICULATING INTERFACES (1995)

Polyethylene wear can be shown as a problem in long-term joint replacement. Metal-on-metal bearing is solving this problem, as long-term clinical and experimental investigations demonstrate. To avoid the problem of high friction found in old series, a new Metasul called technique with a smaller diameter was invented. Intermediate results of Weber and our own data show promising outlook for a solution to the wear-induced problem in hip replacement.
A pattern based approach to answering factoid, list and definition questions (2004)

Finding textual answers to open-domain questions in large text collections is a difficult problem. In this paper we concentrate on three types of questions: factoid, list, and definition questions and present two systems that make use of regular expression patterns and other devices in order to locate possible answers. While the factoid and list system acquires patterns in an off-line phase using the Web, the definition system uses a library of patterns identified by corpus analysis to acquire knowledge in an on-line stage for each new question. Results are reported over the question sets from the question answering track of the 2002 and 2003 Text REtrieval Conference (TREC). 1