gebhart/patrepeval huggingface dataset:
Influence of Stage of the Estrous Cycle on Endogenous Opioid Modulation of Luteinizing Hormone, Prolactin, and Cortisol Secretion in the Gilt1 (1986)

Fourteen gilts that had displayed one or more estrous cycles of 18-22 days (onset of estrus = Day 0) and four ovariectomized (OVX) gilts were treated with naloxone (NAL), an opiate antagonist, at 1 mg/kg body weight in saline i.v. Intact gilts were treated during either the luteal phase (L, Day 10-11; n = 7), early follicular phase (EF, Day 15-17; n = 3), or late follicular phase (LF, Day 18-19; n = 4) of the estrous cycle. Blood was collected at 15-min intervals for 2 h before and 4 h after NAL treatment. Serum luteinizing hormone (LH) concentrations for L gilts averaged 0.65 +/- 0.04 ng/ml during the pretreatment period and increased to an average of 1.3 +/- 0.1 ng/ml (p less than 0.05) during the first 60 min after NAL treatment. Serum prolactin (PRL) concentrations for L gilts averaged 4.8 +/- 0.2 ng/ml during the pretreatment period and increased to an average of 6.3 +/- 0.3 ng/ml (p less than 0.05) during the first 60 min after NAL treatment. Serum PRL concentrations averaged 8.6 +/- 0.7 ng/ml and 7.6 +/- 0.6 ng/ml in EF and LF gilts, respectively, prior to NAL treatment, and decreased (p less than 0.05) to an average of 4.1 +/- 0.2 ng/ml and 5.6 +/- 0.4 ng/ml in EF and LF gilts, respectively, during the fourth h after NAL. Naloxone treatment failed to alter serum LH concentrations in EF, LF, or OVX gilts and PRL concentrations in OVX gilts.(ABSTRACT TRUNCATED AT 250 WORDS)
Structure of zeolite beta determined (1988)

The physical structure of zeolite beta, a sorbent and catalyst, has been determined at Exxon Research and Engineering Co. John M. Newsam told a symposium on molecular sieve science that he and his associates used a combination of direct measurements and computer modeling to deduce the very complex structure. Newsam says that zeolite beta is the most complex zeolitic structure determined to date. Although zeolite beta has been in use since it discovery in 1967, the structure had remained unknown until now.
Mechanisms That Regulate Macrophage Burden in Atherosclerosis (2014)

Mononuclear phagocytes (MPs) relevant to atherosclerosis include monocytes, macrophages, and dendritic cells. A decade ago, studies on macrophage behavior in atherosclerotic lesions were often limited to quantification of total macrophage area in cross-sections of plaques. Although technological advances are still needed to examine plaque MP populations in an increasingly dynamic and informative manner, innovative methods to interrogate the biology of MPs in atherosclerotic plaques developed in the past few years point to several mechanisms that regulate the accumulation and function of MPs within plaques. Here, I review the evolution of atherosclerotic plaques with respect to changes in the MP compartment from the initiation of plaque to its progression and regression, discussing the roles that recruitment, proliferation, and retention of MPs play at these different disease stages. Additional work in the future will be needed to better distinguish macrophages and dendritic cells in plaque and to address some basic unknowns in the field, including just how cholesterol drives accumulation of macrophages in lesions to build plaques in the first place and how macrophages as major effectors of innate immunity work together with components of the adaptive immune response to drive atherosclerosis. Answers to these questions are sought with the goal in mind of reversing disease where it exists and preventing its development where it does not.
Synthesis and characterization of as- and s-indacene bridging ligands and their trimethyltin and manganese tricarbonyl derivatives (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and characterization of as- and s-indacene bridging ligands and their trimethyltin and manganese tricarbonyl derivativesWilliam L. Bell, Calvin J. Curtis, Charles W. Eigenbrot Jr., Cortlandt G. Pierpont, John L. Robbins, and James C. SmartCite this: Organometallics 1987, 6, 2, 266–273Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/om00145a007https://doi.org/10.1021/om00145a007research-articleACS PublicationsRequest reuse permissionsArticle Views608Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Pulse chirp control in an actively mode-locked fiber laser using a dual-drive variable-chirp modulator (2002)

We experimentally demonstrate that the chirp imposed on the pulses from an actively mode-locked erbium fiber ring laser can be controlled by using a dual-drive variable-chirp modulator as mode locker.
An Agent-based Framework for Cross-domain Cooperation of Virtual Enterprise (2003)

Virtual enterprise cross-domain cooperation and inner-domain cooperation have been implemented using an identical method, as the significant differences between them have been neglected. Based on the analysis of why the agent-based mechanism is suitable and only suitable for cross-domain cooperation of virtual enterprise, an agent-based framework is proposed. In this framework, there is a service-information Supply-Demand Center (SDC) serving as a service information medium, and Agents are responsible for cooperative partner selecting before cooperation and interaction during cooperation. Allocation strategy, negotiation strategy and basic interaction models are also presented. Finally, the application of the framework in ECCS (E-Commerce oriented Cooperative System) and Webflow, which are our two workflow-based cooperative systems, is introduced. The framework can make enterprises cooperate with other heterogeneous systems as well as inherit their existing management systems.
Expression of tumor necrosis factor in human acute cardiac rejection. An immunohistochemical and immunoblotting study. (1991)

The authors performed an immunohistochemical study on expression of tumor necrosis factor alpha (TNF alpha) in endomyocardial biopsies from human cardiac allografts. TNF alpha immunoreactivity was found in 45% biopsies with mild acute rejection, in 83% biopsies with focal moderate rejection, in 80% biopsies with diffuse moderate rejection. Biopsies with absent rejection did not show immunoreactive cells. In mild rejection, positive cells were few and scanty monocytes and macrophages (MAC-387 and LN5 positive cells) and T lymphocytes (UCHL-1/CD45 RO positive cells) (up to 20% of all infiltrating cells). Expression of major histocompatibility complex (MHC) class II antigens on infiltrating and endothelial cells occurred earlier and independent of TNF alpha reactivity. Number of immunoreactive cells increased in moderate rejection (up to 50%). Immunoreactivity was also present in nonpigmented macrophages in part of the biopsies with resolving rejection (45%). The authors conclude that TNF alpha is expressed in acute cardiac rejection by immunologically activated inflammatory cells. Immunoreactive cells increase in number with increasing severity of the reaction.
Cloning and organization of seven arginine biosynthesis genes from Neisseria gonorrhoeae (1989)

A genomic library for Neisseria gonorrhoeae, constructed in the lambda cloning vector EMBL4, was screened for clones carrying arginine biosynthesis genes by complementation of Escherichia coli mutants. Clones complementing defects in argA, argB, argE, argG, argIF, carA, and carB were isolated. An E. coli defective in the acetylornithine deacetylase gene (argE) was complemented by the ornithine acetyltransferase gene (argJ) from N. gonorrhoeae. This heterologous complementation is reported for the first time. The carAB operon from E. coli hybridized with the gonococcal clones that carried carA or carB genes under conditions of high stringency, detecting 80% or greater similarity and showing that the nucleotide sequence of the carbamoylphosphate synthetase genes is very similar in these two organisms. Under these conditions for hybridization, the gonococcal clones carrying argB or argF genes did not hybridize with plasmids containing the corresponding E. coli gene. Cocomplementation experiments established gene linkage between carA and carB. Clones complementing a gene defect in argE were also able to complement an argA mutation. This suggests that the enzyme ornithine acetyltransferase from N. gonorrhoeae (encoded by argJ) may be able to complement both argA and argE mutations in E. coli. The arginine biosynthesis genes in N. gonorrhoeae appear to be scattered as in members of the family Pseudomonadaceae.
Digital microfluidic operations on micro-electrode dot array architecture (2011)

As digital microfluidics-based biochips find more applications, their complexity is expected to increase significantly owing to the trend of multiple and concurrent assays on the chip. There is a pressing need to deliver a top-down design methodology that the biochip designer can leverage the same level of computer-aided design support as the semi-conductor industry now does. Moreover, as microelectronics fabrication technology is scaling up and integrated device performance is improving, it is expected that these microfluidic biochips will be integrated with microelectronic components in next-generation system-on-chip designs. This study presents the analysis and experiments of digital microfluidic operations on a novel electrowetting-on-dielectric-based 'micro-electrode dot array architecture' that fosters a development path for hierarchical top-down design approach for digital microfluidics. The proposed architecture allows dynamic configurations and activations of identical basic microfluidic unit called 'micro-electrode cells' to design microfluidic components, layouts, routing, microfluidic operations and applications of the biochip hierarchically. Fundamental microfluidic operations have been successfully performed by the architecture. In addition, this novel architecture demonstrates a number of advantages and flexibilities over the conventional digital microfluidics in performing advanced microfluidic operations.
Maintenance of quality in shell eggs by thermostabilization (1950)

This report is part of the material submitted by the author to the Graduate School of the University of Wisconsin to complete the requirements for he degree of Doctor of Philosophy, December, 1950--P. [3].
Oxidative degradation of dihydrofolate and tetrahydrofolate (1970)

7,8-Dihydrofolate has been degraded oxidatively using ferricyanide under anaerobic conditions. Three reaction pathways have been found for this oxidation, and these pathways can be controlled by variation of the pH and by the nature of the buffer anion. At pH 9, treatment of dihydrofolate with two equivalents of ferricyanide leads to quantitative formation of folate. At pH 5.6 in morpholinoethanesulfonic acid buffer, the same reactants produce p-aminobenzoylglutamate, dihydroxanthopterin, and formaldehyde. Each of these products has been identified, and isolated in high yield. 6-Formyldihydropterin can be isolated by oxidation of dihydrofolate in either phosphate or carboxylic acid buffers. This compound does not appear to be an intermediate in the formation of dihydroxanthopterin under the conditions of our experiments. Tetrahydrofolate was also degraded oxidatively using ferricyanide. Although it is more susceptible to cleavage than is dihydrofolate, tetrahydrofolate gives similar products. In addition, moderate quantities of pterin were isolated from oxidation of tetrahydrofolate at pH 5.6.
<i>Environmental Science & Technology Letters</i> Presents the 2015 Excellence in Review Awards (2015)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTEnvironmental Science & Technology Letters Presents the 2015 Excellence in Review AwardsBruce E. LoganCite this: Environ. Sci. Technol. Lett. 2015, 2, 11, 302Publication Date (Web):October 20, 2015Publication History Received15 October 2015Published online20 October 2015Published inissue 10 November 2015https://pubs.acs.org/doi/10.1021/acs.estlett.5b00280https://doi.org/10.1021/acs.estlett.5b00280editorialACS PublicationsCopyright © 2015 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1420Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (166 KB) Get e-AlertscloseSUBJECTS:Environmental science,Quality management Get e-Alerts
Halide perovskites: A dark horse for direct X‐ray imaging (2020)

Abstract The high cost and difficulty of fabricating high‐quality, thick, large‐area X‐ray absorbers limit their widespread applications in flat‐panel direct hard X‐ray imaging. Then it comes to the recently rising halide perovskites, which show large carrier mobility and lifetime, contain high atomic number elements and are solution processible, making them ideal for large‐area direct hard X‐ray imaging. Over the past few years, direct X‐ray detectors based on a variety of perovskites have been developed, showing impressive progress in achieving high sensitivity and low detection limit. Alongside the developments, the underlying correlations between the intrinsic properties of the perovskites and their X‐ray detection performance have been intensively studied, providing valuable information to tackle the remaining challenges, such as large dark current, baseline drifting and so forth. However, it is surprising to find that there have been no efforts to bring together a comprehensive review and comparative analysis on these previous research endeavors, and some general principles and guidelines of engineering the perovskites toward advanced X‐ray detectors have yet to be creamed off. Here, recent advances in engineering perovskites for direct X‐ray detection are reviewed in the hope of providing fundamental understanding of this fast‐developing field. First, the operation principles of direct X‐ray detectors targeting flat‐panel X‐ray imaging will be introduced, particularly relevant to perovskite materials. Then, recent innovative works regarding the preparation and manipulation of single‐crystalline and poly‐crystalline perovskites are discussed in detail, through which specific effects of the intrinsic properties of the perovskite upon X‐ray detection are highlighted. This is followed by a summary of the review and outlook of future directions. image
Contact physics of gold microcontacts for MEMS switches (1999)

This work presents a study of gold metallic contacts regarding contact resistance, heat dissipation, and surface damage in the normal-force regime of tens to hundreds of /spl mu/N, which is typical of the contact forces from microactuation. The purpose of this work is to present the micromechanical switch designer with practical information on gold contact phenomena in this force regime, as most work in micrometallic contacts has focused on contact forces greater than 1 mN. Results indicate actuation forces of several hundred /spl mu/N are required for reliable fully metallic contacts, with resistance and current carrying ability primarily dependent on morphology, thermal management, and nm-depth material properties of the contact electrodes.
A tabletop femtosecond time-resolved soft x-ray transient absorption spectrometer (2008)

A laser-based, tabletop instrument is constructed to perform femtosecond soft x-ray transient absorption spectroscopy. Ultrashort soft x-ray pulses produced via high-order harmonic generation of the amplified output of a femtosecond Ti:sapphire laser system are used to probe atomic core-level transient absorptions in atoms and molecules. The results provide chemically specific, time-resolved dynamics with sub-50-fs time resolution. In this setup, high-order harmonics generated in a Ne-filled capillary waveguide are refocused by a gold-coated toroidal mirror into the sample gas cell, where the soft x-ray light intersects with an optical pump pulse. The transmitted high-order harmonics are spectrally dispersed with a homebuilt soft x-ray spectrometer, which consists of a gold-coated toroidal mirror, a uniform-line spaced plane grating, and a soft x-ray charge coupled device camera. The optical layout of the instrument, design of the soft x-ray spectrometer, and spatial and temporal characterizations of the high-order harmonics are described. Examples of static and time-resolved photoabsorption spectra collected on this apparatus are presented.
Charge dynamics in silicon nitride/silicon oxide double layers (2001)

Transport of positive charge deposited by a corona discharge on the open nitride surface of a silicon nitride (150 nm)/silicon oxide (300 nm) double layer on silicon substrate is studied by determining the location of the charge centroid with a capacitance–voltage method used in conjunction with surface-potential measurements. At temperatures of about 400 °C, the charge is mobile in the nitride and a large part of it is eventually trapped at the nitride/oxide interface while some of the charge reaches the substrate through the oxide. Indications are that at this temperature the mean free path of positive charges in the nitride and oxide layers is comparable to the layer thicknesses, but much shorter in the nitride at lower temperatures.
Tetraaminoethylenes as Strong Electron Donors (1968)

Abstract Depending on the nature of the electron acceptor and of the tetraaminoethylene (TAE), the electron pairs of the ethylenic double bond (A), of the nitrogen (B), or of the entire electronic system (C) of TAE react with the acceptor. Thus oxidizing agents convert TAE into the mono‐and dications TAE + and TAE 2+ by path (A); acids add on to the ethylenic carbon (A) or the amine nitrogen (B) (the addition of acid is often followed by cleavage of the CC or CN bond); organic π‐electron acceptors from deeply colored donor‐acceptor complexes with TAE (C).
Ehrlichiosis with pancytopenia and ARDS. (1995)

As illustrated by the case described in this report, the possibility of ehrlichiosis should be considered in the differential diagnosis of sulfasalazine toxicity/drug fever and other febrile illnesses presenting with pancytopenia/leukopenia and pulmonary abnormalities, when patients have been exposed to known tick-infested areas. Furthermore, the possibility of delayed serologic confirmation of Ehrlichia infection should be integrated into the diagnostic process as well.
In vivo role of lipid adducts on Wingless (2008)

Two lipids (palmitate and palmitoleic acid) are appended onto Wnt proteins. It has been suggested that palmitate is required for signalling, whereas palmitoleic acid is necessary for progression through the secretory pathway. By mutating the relevant amino acids, we have investigated how these adducts contribute to the secretion and signalling activity of Wingless, the main Drosophila member of the Wnt family. Analysis of Wingless with a Cysteine 93 to Alanine mutation ([C93A]Wingless) shows that palmitoylation is essential for signalling activity in vivo (as well as in cultured cells). Moreover, without palmitate, Wingless fails to reach the surface of imaginal disc cells and, as electron microscopy (EM) analysis suggests, appears to accumulate in the endoplasmic reticulum (ER). Artificial targeting of palmitate-deficient Wingless to the plasma membrane does not rescue signalling activity. Therefore, palmitate at C93 has a dual role: in secretion and signalling. From our analysis of [S239A]Wingless, which lacks a conserved residue shown to be acylated in Wnt3a, we infer that palmitoleic acid is not, as previously suggested, absolutely required for secretion. Nevertheless, this mutant has poor signalling activity, suggesting that palmitoleic acid contributes significantly to signalling. We suggest that the overall level of lipidation affects signalling activity.
Metal dusting of nickel-based alloys (1998)

The carburization behavior of nine commercial nickel-based alloys and four iron-nickel-chromium alloys was investigated at 650°C in a carburizing carbon monoxide (CO)-H 2 hydrogen oxide (H 2 O) gas with a carbon activity (a c ) of a c > 1. The iron-nickel-chromium alloys suffered severe metal dusting after a very short test period. Nickel-based alloys were generally less susceptible to metal dusting than iron-based alloys. Nickel-based alloys with chromium concentrations of 25% and above, on the other hand, showed no significant evidence of metal dusting even after 10,000 h of exposure. It was found that these alloys were protected against metal dusting by the formation of a dense, self-healing chromia scale, which prevented the penetration of carbon into the base metal.
Intelligent service robot with voice recognition and telepresence capabilities (2015)

The objective of this paper is to propose an intelligent service robot in indoor environment with voice recognition and telepresence capabilities. We have assumed that this model of service robot is used to deliver a drinking cup to the recognized customer from the starting point to the destination. We have developed and introduced 3 main modules to avoid obstacle, to recognize commands and telepresence capabilities based on Google App Engine. The detection of obstacles, which is based on the information from the 3 ultrasonic sensors, uses an Interval type-2 Fuzzy Logic for adopting uncertainty. The main contribution of this research is to provide a complete mechanism of communication model between main controllers to other modules in service robot. We present the results of the experiment of the service robot called BeeBot III which implements our proposed method and we also evaluate its performance.