gebhart/patrepeval huggingface dataset:
A Life of Prayer and Holy Obedience (1983)

In an existential sense, prayer brings us into the holy of holies in the Christian life.We move from the periphery to the center.Edward Payson said: "Prayer is the first thing, the second thing, the third thing necessary to a minister.Pray, then, my dear brother; pray, pray, piay."Sir Thomas Buxton wrote: "You know the value of prayer; it is precious beyond all price.Never, never neglect it."William Penn said of George Fox: "Above all he excelled in prayerThe most awful, living, reverent frame I ever felt or beheld, I must say, was his in prayer."Archbishop Tait said: "I want a life of greater, deeper, truer prayer."Martin Luther declared: "To pray well is the better lirlf of study."And E. M. Bounds called it the great need for the church: "What the church needs today is not more machinery or better, not new organization or more and novel methods, hut men of prayer, men mighty in prayer.The Holy Ghost does not flow through methods, but through men.He does not come on machinery, but on men.He does not anoint plans but menmen of prayer."Most pertinent of all to our subject are the words of William Carey: "Prayersecret, fervent, believing prayer - lies at the root of all personal godliness."Just to underscore how far removed we are from the concern of these witnesses, consider what it would be like to impernent the proposal of Adoniram Judson in our daily lives: "Arrange thy affairs, if possible, so that thou canst leisurely devote two or three hours every day
Static and Dynamic Temperature-Aware Scheduling for Multiprocessor SoCs (2008)

Thermal hot spots and high temperature gradients degrade reliability and performance, and increase cooling costs and leakage power. In this paper, we explore the benefits of temperature-aware task scheduling for multiprocessor system-on-a-chip (MPSoC). We evaluate our techniques using workload characteristics collected from a real system by Sun's Continuous System Telemetry. We first solve the task scheduling problem statically using integer linear programming (ILP). The ILP solution is guaranteed to be optimal for the given assumptions for tasks. We formulate ILPs for minimizing energy, balancing energy, and reducing hot spots, and provide an extensive comparison of their thermal behavior against our technique. Our static solution can reduce the frequency of hot spots by 35%, spatial gradients by 85%, and thermal cycles by 61% in comparison to the ILP for minimizing energy. We then design dynamic scheduling policies at the OS-level with negligible performance overhead. Our adaptive dynamic policy reduces the frequency of high-magnitude thermal cycles and spatial gradients by around 50% and 90%, respectively, in comparison to state-of-the-art schedulers. Reactive thermal management strategies, such as thread migration, can be combined with our scheduling policy to further reduce hot spots, temperature variations, and the associated performance cost.
Erratum to “A Bioinformatics Pipeline for the Analyses of Viral Escape Dynamics and Host Immune Responses during an Infection” (2014)

In the paper titled "A bioinformatics pipeline for the analyses of viral escape dynamics and host immune responses during an infection, " there was an error in Figure This figure has the two Circos plots identical. In this erratum we report the corrected Figure
Swift/UVOT follow-up observation of the blue optical transient MASTER075353.88+174907.6 (2017)

On 2017 Oct 31 the MASTER-Net project detected a very blue optical transient MASTER075353.88+174907.6 (ATel #10915) that had increased by > 4.4 mag in the blue band compared to its quiescent level as determined from observations taken as part of the Sloan survey.
Characterization of isoelectric subspecies of asialo-<i>β</i>2-glycoprotein I (1989)

Isoelectric focusing of purified beta 2-glycoprotein I (beta 2-G-I) revealed five major bands with isoelectric points (pI) between 5.1 and 6.1. Neuraminidase treatment decreased the number of bands to two (pI 8.0 and 8.2). The two asialo subfractions of beta 2-G-I were purified by cation-exchange column chromatography. The more basic isoform II was found to have a higher content of lysine. Western-blot analysis of different plasma samples confirmed the heterogeneity of beta 2-G-I in plasma. Plasma treated with neuraminidase showed two bands irrespective of the number of isoforms as well as of the concentration in native plasma. This led us to the conclusion that human plasma beta 2-G-I consists of two isoproteins that are sialylated to different extents.
Stripmap phase gradient autofocus (2003)

Current sonar autofocus techniques for blur removal originate in the radar community but have not provided a complete solution for Synthetic Aperture Sonar (SAS) imagery. The wide-beam, wide-band nature of SAS imagery makes implementation of Synthetic Aperture Radar (SAR) autofocus techniques difficult. This paper describes a generalisation of the standard Phase Gradient Autofocus (PGA) algorithm used in spotlight SAR that allows operation with stripmap SAS geometries. PGA uses prominent points within the target scene to estimate image blurring and phase errors. We show how PGA can be generalised to work with wide-band, wide-beam stripmap geometries. The SPGA method works by employing wave number domain 2D phase estimation techniques. The 2D phase errors are related to aperture position errors using the wave number transform. Robust sway estimates are obtained by using redundancy over a number of target points. We also present an improved Phase Curvature Autofocus (PCA) algorithm using the wave number transform. Preliminary results from the two algorithms (both on field-collected and simulated data sets) are presented and related to those obtained using previous methods. A discussion of SPGA's benefits over traditional algorithms and the limitations of the SPGA algorithm is presented. The SPGA algorithm was found to perform better than 2-D PCA on both simulated and field-collected data sets. Further testing on a variety of target scenes and imagery is required to investigate avenues of autofocus improvement.
Physical properties of cold‐setting gels formed from heat‐denatured whey protein isolate (1995)

Abstract Cold‐setting gels were formed from a 100 g kg −1 whey protein isolate (WPI) solution (pH 7.0) which had been heated to 90°C for 30 min in the absence of salt. Heating caused the globular protein molecules to unfold and form linear aggregates, but electrostatic repulsion opposed extensive protein‐protein interactions and so prevented gel formation. When the solution containing heat‐denatured proteins was cooled to room temperature and mixed with NaCl (0.2 mol kg −1 ), the electrostatic charges were shielded and a gel formed. The rate of gel formation increased on cooling, which suggests that the major driving force for protein aggregation and gelation is the hydrophobic effect. Once formed, the rigidity of the gels decreased with decreasing temperature, which suggested that non‐hydrophobic forces (eg configurational entropy, hydrogen bonding, van der Waals forces and disulphide bond formation) are more important in determining the final gel rigidity. The turbidity and rigidity of gels formed by adding salt to preheated WPI at room temperature were less than those of gels formed by heating WPI in the presence of salt. The ability of WPI to form cold‐setting gels with relatively low turbidity extends the range of applications of whey proteins as functional ingredients in the food industry.
Optical Antenna Gain 2: Receiving Antennas (1974)

Expressions are derived for the gain of a centrally obscured, circular optical antenna when used as the collecting and focusing optics in a laser receiver which include losses due to (1) blockage of the incoming light by the central obscuration, (2) the spillover of energy at the detector, and (3) the effect of local oscillator distribution in the case of heterodyne or homodyne detection. Numerical results are presented for direct detection and for three types of local oscillator distributions (uniform, Gaussian, and matched) in the case of heterodyne or homodyne detection. The results are presented in several graphs that allow the rapid evaluation of receiver gain for an arbitrary set of telescope and detector parameters. It is found that, for uniform illumination by the LO, the optimum SNR is obtained when the detector radius is approximately 0.74 times the Airy disk radius. The use of an optimized Gaussian (spot size = 0.46 times the Airy disk radius) improves the receiver gain by less than 1 dB. Theuse results are insensitive to the size of the central obscuration.
Development of A Fast Method for Direct Analysis of Intact Synthetic Insulins in Human Plasma: The Large Peptide Challenge (2012)

A simple SPE LC-MS analysis was developed for direct, simultaneous quantification of insulin glargine, detemir, aspart and glulisine.
Alterations in polyphenol oxidase activity during organ redifferentiation in carrot calluses cultured in vitro (1977)

A significant increase in polyphenol oxidase activity occurs in carrot calluses just before or simultaneously with root redifferentiation from the tissue culture cells. The enhancement of polyphenol oxidase activity inherent in redifferentiation (root formation) from calluses is mainly dependent on the appearance of other kinds of polyphenol oxidase which are not detected in calluses unless accompanying redifferentiation. Investigation using agents which have stimulatory, inhibitory, or repressive effects on redifferentiation shows that the elevation of oxidase activity is closely related to the organ forming capacity of carrot calluses.
Modeling Others using Oneself in Multi-Agent Reinforcement Learning (2018)

We consider the multi-agent reinforcement learning setting with imperfect information in which each agent is trying to maximize its own utility. The reward function depends on the hidden state (or goal) of both agents, so the agents must infer the other players' hidden goals from their observed behavior in order to solve the tasks. We propose a new approach for learning in these domains: Self Other-Modeling (SOM), in which an agent uses its own policy to predict the other agent's actions and update its belief of their hidden state in an online manner. We evaluate this approach on three different tasks and show that the agents are able to learn better policies using their estimate of the other players' hidden states, in both cooperative and adversarial settings.
FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer (2020)

FOXE1 functions as a critical tumor suppressor in regulating tumor growth and glycolysis via suppressing HK2 in CRC.
Stilbenoids from<i>Stemona japonica</i> (2006)

Three new dihydrostilbenes, stilbostemins J-L (1-3), and a new dihydrophenanthrene, stemanthrene F (4), were isolated from the roots of Stemona japonica together with two known bibenzyls, 3,5-dihydroxy-4-methylbibenzyl (5) and 3,5-dihydroxy-2'-methoxy-4-methylbibenzyl (6). Their structures were elucidated by spectroscopic analyses. Compounds 3-6 exhibited strong antibacterial activities against Staphylococcus aureus and Staphylococcus epidermidis.
Medication Overuse Headache: Rates and Predictors for Relapse in a 4-year Prospective Study (2004)

We present a prospective 4-year follow-up study of 96 patients with medication overuse headache following withdrawal. Complete datasets were available from 85 patients (89%) 6 months, from 79 patients (82%) 1 year and from 75 patients (78%) 4 years after withdrawal. Twenty-six patients (31%) relapsed within the first 6 months after withdrawal. The number of relapses increased to 32 (41%) 1 year and to 34 (45%) 4 years after withdrawal. The 4-year relapse rate was lower in migraine than in tension-type headache (32% vs. 91%, P<or=0.001) and combination of migraine and tension-type headache (32% vs. 70%, P<or=0.027) and also lower in patients overusing triptans than analgesics (21% vs. 71%, P<or=0.001). The study suggests that the majority of relapses occur within the first year after withdrawal and that the long-term success of withdrawal depends on the type of primary headache and the type of overused medication.
Congenic Mapping of Alcohol and Pentobarbital Withdrawal Liability Loci to a <1 Centimorgan Interval of Murine Chromosome 4: Identification of<i>Mpdz</i>as a Candidate Gene (2002)

Risk for onset of alcoholism is related to genetic differences in acute alcohol withdrawal liability. We previously mapped a locus responsible for 26% of the genetic variance in acute alcohol withdrawal convulsion liability to a >35 centimorgan (cM) interval of murine chromosome 4. Here, we narrow the position of this locus to a <1 cM interval (approximately 1.8 megabase, containing 15 genes and/or predicted genes) using a combination of novel, interval-specific congenic strains and recombinant progeny testing. We report the development of a small-donor-segment congenic strain, which confirms capture of a gene affecting alcohol withdrawal within the <1 cM interval. We also confirm a pentobarbital withdrawal locus within this interval, suggesting that the same gene may influence predisposition to physiological dependence on alcohol and a barbiturate. This congenic strain will be invaluable for determining whether this interval also harbors a gene(s) underlying other quantitative trait loci mapped to chromosome 4, including loci affecting voluntary alcohol consumption, alcohol-induced ataxia, physical dependence after chronic alcohol exposure, and seizure response to pentylenetetrazol or an audiogenic stimulus. To date, Mpdz, which encodes the multiple PSD95/DLG/ZO-1 (PDZ) domain protein (MPDZ), is the only gene within the interval shown to have allelic variants that differ in coding sequence and/or expression. Sequence analysis of 15 standard inbred mouse strains identifies six Mpdz haplotypes that predict three MPDZ protein variants. These analyses, and evidence using interval-specific congenic lines, show that alcohol withdrawal severity is genetically correlated with MPDZ status, indicating that MPDZ variants may influence alcohol withdrawal liability.
Using semantics to identify web objects (2006)

Many common web tasks can be automated by algorithms that are able to identify web objects relevant to the user’s needs. This paper presents a novel approach to web object identification that finds relationships between the user’s actions and linguistic information associated with web objects. From a single training example involving demonstration and a natural language description, we create a parameterized object description. The approach performs as well as a popular web wrapper on a routine task, but it has the additional capability of performing in dynamic environments and the attractive property of being reusable in other domains without additional training.
Target-induced death by apoptosis in human lymphokine-activated natural killer cells (1996)

Activated human natural killer (NK) cells undergo rapid apoptotic cell death after ligand binding to the Fc receptor (CD16). We examined whether human NK cells die after engagement in cytolytic functions. Peripheral blood NK cells, with and without prior activation in vitro with interleukin-2 (IL-2), were tested for the occurrence of cell death after incubation with K562, the prototype NK-sensitive target cell. A proportion (15.2%) of NK cells that were stimulated for 3 days with IL-2 and then incubated for 4 hours with K562 cells showed rapid cell death, but NK cells not stimulated with IL-2 did not. This cell death was found to involve nuclear condensation and fragmentation and DNA cleavage, all of which are characteristic of apoptosis. These data indicate that a proportion of activated human NK cells undergo apoptosis as they engage in target cell lysis. Target-induced NK cell death may represent an important mechanism for regulation of inflammatory processes involving NK cells.
Gas flux through human skin: effect of temperature, stripping, and inspired tension (1985)

The flux of He and O2 through intact adult human skin was measured at various inspired concentrations and skin temperatures. The skin surface was then stripped with cellophane tape to alter the diffusional conductance of the stratum corneum. He flux for stripped skin was used to estimate skin perfusion as a function of local temperature, and diffusional conductance for O2 was estimated from O2 flux and perfusion. The flux of He or O2 at constant skin temperature can be related to inspired concentration by a simple linear model. Increasing surface temperature in the range 33-43 degrees C produced a much larger increase in O2 flux than in He flux for intact skin. Skin stripping greatly increased skin O2 flux. Estimated skin conductance for O2 showed a more marked temperature dependence than estimated skin perfusion. The results suggest that raising skin temperature in the range 38-43 degrees C has only a modest effect on skin perfusion and that stratum corneum conductance may have a major role in the large increase of O2 flux with temperature.
Identification of rat liver phosphatidylinositol synthase as a 21 kDa protein (1994)

Substantial purification of rat liver phosphatidylinositol (PtdIns) synthase has been achieved by a combination of Hecameg extraction, heat treatment, affinity chromatography and chromatography on PBE-94. The activity chromatographs as a single peak which has an apparent molecular mass between 150 and 200 kDa on Sepharose 4B. When analysed by SDS/PAGE, two major bands are seen. The enzyme activity is correlated with a protein band of 21 kDa. A second band, at 51 kDa, is eluted from a PBE-94 column slightly ahead of the activity. Manganese is an absolute requirement for stabilization of activity in the presence of detergent. The effect of manganese is optimal at 0.5 mM; magnesium at a concentration of 10 mM is only minimally effective. Substrate Kms are 1.3 mM and 9.5 microM for inositol and CDP-diacylglycerol respectively. The activity eluting from the PBE-94 column is purified 5000-fold over the post-mitochondrial supernatant.
The digital morphological sampling theorem (2003)

There are potential industrial applications for any methodology which inherently reduces processing time and cost and yet produces results sufficiently close to the result of full processing. It is for this reason that a morphological sampling theorem is important. The morphological sampling theorem described by the authors states: (1) how a digital image must be morphologically filtered before sampling to preserve the relevant information after sampling; (2) to what precision an appropriately morphologically filtered image can be reconstructed after sampling; and (3) the relationship between morphologically operating before sampling and the more computationally efficient scheme of morphologically operating on the sampled image with a sampled structuring element. The digital sampling theorem is developed for the case of binary morphology.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Caveolin-3 Is a Sensitive and Specific Marker for Rhabdomyosarcoma (2005)

Caveolin-3 (Cav-3) is a principal structural protein of caveolae membrane domains. Animal studies have revealed that Cav-3 is expressed in skeletal and cardiac myocytes but absent in other types of cells. Recent studies have shown that abnormalities in the Cav-3 gene are associated with some forms of muscular dystrophy, while skeletal muscle abnormalities have been observed in Cav-3 transgenic and knockout mice. In this study the authors evaluated the distribution of Cav-3 in normal human tissues and compared the expression of Cav-3 with that of myogenin and myoD1 in rhabdomyosarcoma (RMS), malignant mixed mullerian tumor (MMMT), and an array of neoplasms that mimic RMS to assess the utility of Cav-3 as a diagnostic marker for tumors with skeletal muscle differentiation. In nonneoplastic human tissues, crisp membrane staining for Cav-3 was present in cardiac and skeletal myocytes and occasionally in arterial smooth muscle cells and prostatic stromal cells, while other cell types were negative for Cav-3. Eighty-eight percent (21/24) of RMS studied were positive for Cav-3. Positive staining was generally observed in the more maturely differentiated tumor cells but not the primitive tumor cells. Eight of nine cases of MMMT stained strongly with Cav-3 in their rhabdomyosarcomatous component but not in other components. Fifty-four other neoplasms (13 leiomyosarcomas, 8 neuroblastomas, 5 lymphomas, 6 Wilms tumors without skeletal muscle differentiation, 5 Ewing sarcomas, 4 malignant fibrous histiocytomas, 4 angiosarcomas, 6 malignant melanomas, and 3 synovial sarcomas) were negative for Cav-3 expression. Nearly all (96% [23/24]) cases of RMS were positive for myogenin, while 88% (21/24) were positive for myoD1. Primitive tumor cells showed significantly increased expression of myoD1 and myogenin; conversely, more differentiated tumor cells were negative or weakly stained. The rhabdomyosarcomatous component of MMMT stained focally with myogenin and myoD1, in contrast to the strong Cav-3 labeling in these cells. These results demonstrate that Cav-3 is specifically expressed in human cardiac and skeletal myocytes. Furthermore, its high specificity and relatively high sensitivity (88%) for tumors with skeletal muscle differentiation suggest that Cav-3 is a valuable marker for these tumors and may be used to assess the degree of differentiation of RMS and to identify residual tumor cells in post-chemotherapy specimens.
A comparative study between a Rankine cycle and a novel intra-cycle based waste heat recovery concepts applied to an internal combustion engine (2016)

A novel intra-cycle waste heat recovery (ICWHR) methodology, applied to an internal combustion engine is presented in this study. Through a split type thermodynamic cycle design, quasi-isothermal compression of the charge air and isobaric combustion of the air/fuel mixture can be performed separately in two chambers. Within such a design, the exhaust heat can be recovered to the intake air flow between the compression chamber and combustion chamber. Consequently, the recovered energy can be re-utilized in the combustor directly, and an intra-cycle waste heat recovery process can be achieved. To investigate the fundamental aspects of this new methodology, a comparative study between the conventional Rankine based WHR and the new ICWHR was undertaken. Both theoretical and numerical analysis were applied to evaluate the performance characteristics of these two technologies. The ICWHR cycle differs from the Rankine cycle in that an energy conversion subsystem is not necessary since the recovered energy is sent back to the combustion chamber directly, and then the system efficiency is improved significantly. Furthermore, the theoretical results indicate that the full cycle efficiency of ICWHR system is determined by the regeneration effectiveness, the compression ratio and the fuel equivalence ratio, then the limitations of Rankine cycle, such as working fluid selection and system parameter calibration can be avoided mechanically. Finally, through a one dimensional system model, analysis of optimal operation range, system efficiency and the heat transfer behaviours of ICWHR system are discussed in this paper and comparisons made with a Rankine cycle WHR system
Optisches Multisensor-System für die industrielle 3 D-Werkstückerkennung / Optical multi-sensor system for industrial 3 D-workpiece recognition (1990)

Article Optisches Multisensor-System für die industrielle 3 D-Werkstückerkennung / Optical multi-sensor system for industrial 3 D-workpiece recognition was published on December 1, 1990 in the journal tm - Technisches Messen (volume 57, issue JG).