gebhart/patrepeval huggingface dataset:
Denaturation and aggregation of serum proteins and caseins in heated milk (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDenaturation and aggregation of serum proteins and caseins in heated milkDouglas G. DalgleishCite this: J. Agric. Food Chem. 1990, 38, 11, 1995–1999Publication Date (Print):November 1, 1990Publication History Published online1 May 2002Published inissue 1 November 1990https://pubs.acs.org/doi/10.1021/jf00101a001https://doi.org/10.1021/jf00101a001research-articleACS PublicationsRequest reuse permissionsArticle Views678Altmetric-Citations114LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Primitivwurzeln (1998)

In diesem Paragraphen werden die natürlichen Zahlen m charakterisiert, für die die Einheitengruppe E(ℤ/mℤ) des Restklassenrings ℤ/mℤ zyklisch ist. Außerdem wird für jedes m ∈ ℕ die maximale Elementordnung in der Gruppe E(ℤ/mℤ) berechnet.
Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high‐fat‐diet‐fed mice (2014)

The mineralocorticoid receptor (MR) controls adipocyte function, but its role in the conversion of white adipose tissue (WAT) into thermogenic fat has not been elucidated. We investigated responses to the MR antagonists spironolactone (spiro; 20 mg/kg/d) and drospirenone (DRSP; 6 mg/kg/d) in C57BL/6 mice fed a high-fat (HF) diet for 90 d. DRSP and spiro curbed HF diet-induced impairment in glucose tolerance, and prevented body weight gain and white fat expansion. Notably, either MR antagonist induced up-regulation of brown adipocyte-specific transcripts and markedly increased protein levels of uncoupling protein 1 (UCP1) in visceral and inguinal fat depots when compared with the HF diet group. Positron emission tomography and magnetic resonance spectroscopy confirmed acquisition of brown fat features in WAT. Interestingly, MR antagonists markedly reduced the autophagic rate both in murine preadipocytes in vitro (10(-5) M) and in WAT depots in vivo, with a concomitant increase in UCP1 protein expression. Moreover, the autophagy repressor bafilomycin A1 (10(-8) M) mimicked the effect of MR antagonists, increasing UCP1 protein expression in primary preadipocytes. Hence, we showed that adipocyte MR regulates brown remodeling of WAT through a modulation of autophagy. These results provide a rationale for the use of MR antagonists to prevent the adverse metabolic consequences of adipocyte dysfunction.
Effect of taurine on oxidative stress and apoptosis-related protein expression in trinitrobenzene sulphonic acid-induced colitis (2008)

Ulcerative colitis (UC) is a multi-factorial inflammatory disease of the colon and rectum. The present study was undertaken to investigate the effect of taurine, an anti-oxidant amino acid, on oxidative stress and the expression of apoptosis-related proteins, pro-apoptotic Bax and anti-apoptotic B cell lymphoma-2 (Bcl-2) in colon tissue in rats with 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis. Rats received taurine (1.5% w/v) in drinking water for 15 days before and 15 days after administration of TNBS solution. Then, colonic myeloperoxidase (MPO) activity, malondialdehyde (MDA) and glutathione (GSH) levels, and Bax and Bcl-2 expression were measured. TNBS-induced colitis caused significantly increased MPO activity and MDA levels and decreased GSH levels in colon tissue compared to controls. Increase in Bax expression and decrease in Bcl-2 expression were detected in colon of rats with TNBS-induced colitis. Taurine treatment was associated with amelioration in macroscopic and microscopic colitis scores, decreased colonic MPO activity and MDA levels and increased GSH levels in TNBS-induced colitis. In addition, taurine reduced the expression of Bax and prevented the loss of Bcl-2 proteins in colon tissue of rats with TNBS-induced colitis. The results of this study show that taurine administration may exert beneficial effects in UC by decreasing inflammatory reactions, oxidative stress and apoptosis.
Effect of Sunlight on Disinfection of the Equipment for Chicken Management (1982)

Experiments were carried out to evaluate the efficacy of sunlight on disinfection of surface of the equipment for chicken management. Efficacy of disinfection by exposure to sunlight was observed when the equipment was exposed to direct sun-beam in summer during several days continuously. It was required low degree of contamination with microoganisms on surface of the equipment prior to exposure. No effect was recorded when exposure was conducted in a shady corner and to direct sun-beam in winter.
Molecular Genetics Minireview of Demyelination: New Wrinkles on an Old Membrane (1997)

into question the common assumption that the layersDepartment of Neurology of the myelin sheath have a high electrical resistance.The University of Pennsylvania Medical Center The resistance may actually be low, as has been shownPhiladelphia, Pennsylvania 19104–6077 in the CNS myelin surrounding the Mauthner axon ingoldfish (Funch and Faber, 1984).The Structure and Function of Myelin
Efficient time-domain simulation of frequency-dependent elements (1996)

We describe an efficient algorithm for the time-domain simulation of elements described by causal impulse responses. The computational bottleneck in the simulation of such elements is the need to compute convolutions at each time point. Hence, direct approaches for the simulation of such elements require time O(N^2), where N is the length of the simulation. We apply ideas from approximation theory to reduce this complexity to O(N \log N) while maintaining double-precision accuracy. The only restriction imposed by our method is that the impulse response h(t) gets ``smoother'' as t goes to infinity. Essentially all physically reasonable impulse responses have this characteristic. The ideas presented can also be applied to time-domain simulation of elements described in the frequency domain, including those characterized by measured data. In this paper, we demonstrate the efficiency of the algorithm by applying it to the simulation of lossy transmission lines.
Antimicrobial surfaces and their potential in reducing the role of the inanimate environment in the incidence of hospital-acquired infections (2009)

Environmental surfaces and their role in the epidemiology of hospital-acquired infections (HAIs) have become an area of great scientific interest, particularly in light of the much publicised cases of infections due to methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile in UK hospitals. This feature article sets out to examine the role of surfaces and the inanimate environment in the spread of HAIs, and looks at various antimicrobial techniques being researched to reduce microbial contamination of surfaces. Preventative measures such as coatings which reduce initial microbial adhesion to surfaces will be considered alongside actively antimicrobial measures which inactivate microorganisms already adherent to a surface. The principal focus of this feature article will be given to light-activated antimicrobial surfaces such as the photocatalyst TiO2 and surfaces with embedded photosensitisers. Surfaces which release antimicrobial compounds or metal ions such as silver and copper are also examined, alongside materials which kill microbes upon contact. The widespread research and development of these antimicrobial surfaces is of great importance in maintaining acceptable levels of hygiene in hospitals and will help to fight the spread of HAIs via the contamination of inanimate surfaces in the healthcare environment.
Birth Prevalence and Natural History of Congenital Cytomegalovirus Infection in a Highly Seroimmune Population (2009)

The results of this large newborn screening study in a population with high CMV seroimmunity provide additional evidence that congenital CMV disease occurs in populations with high seroprevalence rates, with a similar incidence of CMV-related hearing loss to that reported in the offspring of women from populations in developed countries with lower rates of seroimmunity to CMV.
Expression of Receptor for Advanced Glycation End Products in Sarcoid Granulomas (2006)

We showed the association of RAGE and its ligands with sarcoidosis and suggest that an intrinsic genetic factor could be in part involved in its expression. In Italian patients, the -374 T/A polymorphism seems to be significantly associated with this disease.
Lectores, desarrollo tecnológico y bibliotecarios: ¿preparados para el cambio? (2012)

Este trabajo tiene como propósito principal presentar el estado actual sobre los retos y oportunidades que le imponen, al sector bibliotecario, un entorno tecnológico cambiante. El análisis de la literatura se centra en tres elementos fundamentales para el desarrollo de las bibliotecas en la actualidad: los lectores, razón de ser de la institución, los bibliotecarios, como mediadores y facilitadores del proceso informativo y formativo y las tecnologías que favorecen el desarrollo de nuevos servicios y productos. En el documento se reflexionan sobre estos aspectos, exponiendo la necesidad de que el bibliotecario reconozca el papel a desempeñar en la actualidad para que su labor siga siendo relevante.
Evidence for an Imino Intermediate in the DNA Polymerase β Deoxyribose Phosphate Excision Reaction (1996)

A recent study demonstrated that rat DNA polymerase beta (beta-pol) releases 5'-deoxyribose phosphate (dRP) termini from preincised apurinic/apyrimidinic DNA, a substrate generated during certain types of base excision repair. This catalytic activity resides within the amino-terminal, 8-kDa domain of beta-pol and occurs via beta-elimination as opposed to hydrolysis (Matsumoto, Y., and Kim, K. (1995) Science 269, 699-702). The latter finding suggested that the dRP excision reaction might proceed via an imine intermediate. In order to test this hypothesis, we attempted to trap beta-pol on preincised apurinic/apyrimidinic DNA using NaBH4 as the reducing agent. Both 8-kDa domain-DNA and intact beta-pol-DNA complexes were detected and identified by autoradiography coupled to immunoblotting. Our results indicate that the chemical mechanism of the beta-pol dRpase reaction does proceed through an imine enzyme-DNA intermediate and that the active site residue responsible for dRP release must therefore contain a primary amine.
Equalization and detection for nonlinear recording channels with correlated noise (1999)

At high recording densities, signal nonlinearity due to both the medium and the magnetoresistive head and correlated noise due to the medium and the equalization process, substantially degrade the error-rate performance of the Viterbi algorithm (VA). This paper describes a method for dealing with both problems by simultaneously adapting the equalizer, its target and the VA branch metrics. A monic constraint is employed to locate a target that limits noise correlation at the input to the VA. Pattern-dependent offsets, rather than actual VA ideal values, are adaptively determined to account for channel nonlinearity in the VA. The effectiveness of these techniques is demonstrated on very high density data collected from a spin stand.
An Open Hypermedia System for Multimedia Applications (1992)

In this paper we present an architecture for an open hypermedia system that supports integrated multimedia applications. Besides support for the organisation and the manipulation of heterogeneous data types like text, raster pictures, vector graphics, video, animation and sound, open hypermedia systems include techniques to extend the system with new data types and tools as basic functionality. Starting from a requirement analysis for an open hypermedia system, we identify the different task scopes of the system. We then map the task scopes onto a conceptual architecture and describe the different architectural and descriptive elements resulting from this mapping. The systems’ architectural elements are the components mass storage, object, session and presentation-interaction management. On the descriptive side the HyperPicture concept provides information objects, extents, functions bindings, events and actions as atomic elements for the definition of the interaction between user, operating system and data objects. Furthermore, we describe a prototype implementation of the HyperPicture concepts being developed at the Computer Graphics Center (ZGDV), the HyperPicture-Toolkit. Moreover, an application built on top of this toolkit — the satellite data retrieval system SpacePicture — illustrates the use and the potential of the HyperPicture-Toolkit and its underlying concepts. Finally, this paper contains a brief description of open issues and further development.
A new scalable directory architecture for large-scale multiprocessors (2002)

The memory overhead introduced by directories constitutes a major hurdle in the scalability of cc-NUMA architectures, which makes the shared-memory paradigm unfeasible for very large-scale systems. This work is focused on improving the scalability of shared-memory multiprocessors by significantly reducing the size of the directory. We propose multilayer clustering as an effective approach to reduce the directory-entry width. Detailed evaluation for 64 processors shows that using this approach we can drastically reduce the memory overhead, while suffering a performance degradation we similar to previous compressed schemes (such as Coarse Vector). In addition, a novel two-level directory architecture is proposed in order to eliminate the penalty caused by these compressed directories. This organization consists of a small Full-Map first-level directory (which provides precise information for the most recently referenced lines) and a compressed second-level directory (which provides in-excess information). Results show that a system with this directory architecture can achieve the same performance as a multiprocessor with a big and non-scalable Full-Map directory with a very significant reduction of the memory overhead.
The Bases of Goal Setting in the Self-regulation of Hypertension (2005)

We apply a new methodology to investigate goal setting by hypertensive patients that uncovers the reasons why people have a goal to manage hypertension or not (e.g. to reduce/maintain one's current blood pressure). The reasons are found to consist of superordinate goals in support of one's focal hypertension goal and the hierarchical mental network underlying the superordinate goals. We show that, not only do such superordinate goals influence patients' beliefs, feelings and decisions, but the relationships among superordinate goals are particularly efficacious in the formation of beliefs and attitudes, as well as intentions to self-regulate hypertension and actual efforts in doing so. Hypotheses were tested on a sample of 219 patients at a university-based hypertension clinic.
Parametric Study of Planar Artificial Magnetic Conductor Surface (2006)

In this paper, a quasi-static technique based on a simple transmission line model is used for studying a planar artificial magnetic conductor (AMC) surface. The results of this quasi-static model are verified with previously published results. This quasi-static solution is used as a fast efficient technique to obtain the effects of the different parameters on the center frequency and the operating bandwidth of a planar AMC surface. These parameters include the patch width, the gap width between the patches, the relative permittivity of the substrate and the substrate thickness
Role of the protein kinase PKR in the inhibition of varicella-zoster virus replication by beta interferon and gamma interferon (2004)

Varicella-zoster virus (VZV) is sensitive to type I and type II interferons (IFNs), which mediate antiviral effects. In this study, it was demonstrated that IFN-beta and IFN-gamma inhibited the replication of VZV in vitro. Although IFN-beta was more effective than IFN-gamma, the level of inhibition of VZV replication achieved by the combination of both IFNs was more than additive and it was concluded that these two cytokines acted synergistically. Expression of the IFN-induced, double-stranded RNA-activated protein kinase PKR and its phosphorylation level were not modulated strongly during ongoing replication of VZV. However, in the presence of IFN-beta, but not IFN-gamma, PKR expression and its phosphorylation were increased, explaining in part the inhibition of virus replication by IFNs. The expression of herpes simplex virus Us11, a viral protein with several functions, including prevention of PKR activation, strongly increased the level of VZV replication.
Qualifying non-volatile register files for embedded systems through compiler-directed write minimization and balancing (2015)

Recent research shows non-volatile flip-flops can be attached to register files to hold computation state thus enabling fast recovery upon power failure. However, the endurance limitation of NVM cells challenges their usage for holding register values that are frequently updated during program execution. To extend the lifetime of non-volatile register files, we propose two compiler-directed optimizations. First, through analyzing the register access patterns in frequently executed loops, a minimum set of registers is identified to be periodically written to NVM cells, thus minimizing the total number of writes to the NVM register file. Meanwhile, the register mapping is also adjusted to enable an efficient dynamic register rotation to further balance the writes to different NVM registers. Experimental studies show that the proposed two techniques can significantly extend the lifetime of non-volatile registers, thus qualifying them for various embedded systems.
MECHANISMS OF HOPPERBURN: An Overview of Insect Taxonomy, Behavior, and Physiology (2004)

Hopperburn is a non-contagious disease of plants caused by the direct feeding damage of certain leafhoppers and planthoppers. Although long studied, especially with Empoasca spp. leafhoppers (Cicadellidae: Typhlocybinae), the mechanisms underlying hopperburn have only recently been elucidated. Hopperburn is caused by a dynamic interaction between complex insect feeding stimuli (termed hopperburn initiation) and complex plant responses (termed the hopperburn cascade). Herein we review the nature of the feeding stimuli in hopperburn initiation, especially for Empoasca spp., which we also compare with the planthopper Nilaparvata lugens. Contrary to previous reports, Empoasca hopperburn is not caused solely by toxic saliva. Instead, it is caused by a plant wound response triggered by a unique type of stylet movement, which is then exacerbated by saliva. Electrical penetration graph monitoring has revealed that all Empoasca spp. are cell rupture feeders, not sheath feeders, and that certain tactics of that feeding strategy are more damaging than others. Measuring the proportions of the most damaging feeding led to development of a resistance index, the Stylet Penetration Index, which can predict hopperburn severity in different plants or under different environmental conditions and can supplement or replace traditional, field-based resistance indices.
The role of vascular endothelial growth factor in lung development (2010)

Lung development is affected by many factors, and vascular endothelial growth factor is a specially growth factor which has a broad impact on endothelial cell function, it can promote the proliferation and differentiation of cells,as well as promoting angiogenesis and increasing permeability of micro vascular. Further more, it participates in pulmonary vascular development, alveolarization, surfactant synthesis and lung maturity. Thus vascular endothelial growth factor plays an important role in the establishment of normal lung morphology and function, and its abnormal expression may induce abnormal lung development.

Key words: 
Vascular endothelial growth factors; Lung development; Hypoxia-inducible factor
Observation of Majorana Fermions in a Nb-InSb Nanowire-Nb Hybrid Quantum Device (2012)

We report on the observation of excitation of Majorana fermions in a Nb-InSb nanowire quantum dot-Nb hybrid system. The InSb nanowire quantum dot is formed between the two Nb contacts by weak Schottky barriers and is thus in the regime of strong couplings to the contacts. Due to the proximity effect, the InSb nanowire segments covered by superconductor Nb contacts turn to superconductors with a superconducting energy gap $Δ^*$. Under an applied magnetic field larger than a critical value for which the Zeeman energy in the InSb nanowire is $E_z\sim Δ^*$, the entire InSb nanowire is found to be in a nontrivial topological superconductor phase, supporting a pair of Majorana fermions, and Cooper pairs can transport between the superconductor Nb contacts via the Majorana fermion states. This transport process will be suppressed when the applied magnetic field becomes larger than a second critical value at which the transition to a trivial topological superconductor phase occurs in the system. This physical scenario has been observed in our experiment. We have found that the measured zero-bias conductance for our hybrid device shows a conductance plateau in a range of the applied magnetic field in quasi-particle Coulomb blockade regions.
Economical analysis of a new gas to ethylene technology (2007)

Ethylene is one of the most important petrochemical intermediates and feedstocks\nfor many different products. The motivating force of this work is to compare a new\nprocess of ethylene production developed at Texas A&M University to the most common\nprocesses. Ethylene is produced commercially using a wide variety of feedstocks ranging\nfrom ethane to heavy fuel oils. Of them, the thermal cracking of ethane and propane\nusing a fired tubular heater is the most common process in the United States. In Europe\nand Japan, where natural gas is not abundant, thermal cracking of naphtha using a fired\nheater is the most common process. In addition to these processes; ethylene could also be\nproduced from crude oil by autothermic and fluidized bed techniques and from coal and\nheavy oils by synthesis from carbon monoxide and hydrogen.\nAt Texas A&M University, a group of researchers developed a new process that\ncan convert natural gas into liquids (GTL) or to ethylene (GTE). This technology is a\ndirect conversion method that does not require producing syngas. When selecting a\nprocess for ethylene production, the dominant factor is the selection of hydrocarbon\nfeedstocks. Based upon plant capacity of 321 million pounds of ethylene per year, this\nstudy has shown that using natural gas, as a feedstock, is more economical than using\nethane, propane, naphtha, and other feedstocks. Therefore, it is more economical to convert natural gas directly to ethylene than separating ethane or propane from natural\ngas and then converting it to ethylene. A process simulation package ProMax is used to\nrun the GTE process; and a software program, Capcost, is used to evaluate fixed capital\ncosts of the GTE process. Finally, the cost index is used to update the cost of the other\nprocesses of ethylene production today.