gebhart/patrepeval huggingface dataset:
Failover and Load Sharing in SIP Telephony (2004)

We apply some of the existing web server redundancy techniques for high service availability and scalability to the relatively new IP telephony context. The paper compares various failover and load sharing methods for registration and call routing servers based on the Session Initiation Protocol (SIP). In particular, we consider the SIP server failover techniques based on the clients, DNS (Domain Name Service), database replication and IP address takeover, and the load sharing techniques using DNS, SIP identifiers, network address translators and servers with same IP addresses. Additionally, we present an overview of the failover mechanism we implemented in our test-bed using our SIP proxy and registration server and the open source MySQL database.
Construction Techniques for Electrically Conductive Heated Pavement Systems (2018)

Ice and snow accumulation on airport paved surfaces has the potential to cause fatal accidents and monetary loss due to flight delays and cancellations. Traditional de-icing methods involving the application of chemicals or salt and employing large machines can create negative environmental and structural impact on airport infrastructure systems. These methods are also considered to be labor intensive and a safety hazard, especially in congested areas such as aprons. Heated pavement systems using electrically conductive concrete (ECON) have been proposed as a promising alternative technology for preventing ice accumulation and mitigating the adverse effects of using traditional snow removal methods. The objective of this study is to present information and experience about the design, construction procedures, and performance of heated pavement systems using jointed plain concrete pavements for the construction of large-scale heated airport pavements. It is based on detailed field demonstration of the electrically conductive concrete (ECON) heated pavement system (HPS) at the north general aviation (GA) apron of the Des Moines International Airport (DSM) in Iowa, in collaboration with contractors, and airport staff representatives. The expected outcome of this study will help the construction industry to better understand optimal ECON construction methods.
EAE/ASE Recommendations for Image Acquisition and Display Using Three-Dimensional Echocardiography (2012)

<b>Context</b> Current guidelines recommend the use of aldosterone antagonists (AA) in patients with moderately severe to severe symptoms [New York Heart Association (NYHA) class III to IV] and systolic heart failure.<br><b>Objective</b> To determine the efficacy of AA in improving ejection fraction (EF) and functional capacity and to assess whether this effect was influenced by baseline NYHA classification.<br><b>Study design</b> Meta-analysis of randomized controlled trials. Data extraction performed independently by two researchers.<br><b>Data Sources</b> MEDLINE and the Cochrane Library.<br><b>Study Selection</b> Prospective randomized controlled trials using AA were included if there was a clear description of the baseline NYHA classification and change in EF in patients from study initiation to completion.<br><b>Results</b> Data from 1,575 patients enrolled in fourteen studies were included. Overall, there was a weighted mean improvement in EF of 3.2% and in NYHA classification of 0.13 in subjects treated with AA when compared to controls (p<0.001). A mixed effects meta-regression analysis revealed that baseline NYHA was not predictive of improvement in EF (p=0.67) nor NYHA status (p=0.18).</br><b>Conclusions</b> The results of this meta-analysis suggest that AA is associated with significant improvements in EF and functional class independent of baseline functional capacity. This supports and expands on the recently published EMPHASIS-HF trial and suggests that the current restriction of AA use to patients with NYHA class III-IV symptoms should be reconsidered.<br>
The recall in sioux city, iowa (1920)

Abstract The story of the recall in Sioux City can now be told impartially. It is a contribution to the slender testimony on the subject.
Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer's Disease (2009)

Synapse loss occurs early in Alzheimer's disease (AD) and is considered the best pathological correlate of cognitive decline. Ephrins and Eph receptors are involved in regulation of excitatory neurotransmission and play a role in cytoskeleton remodeling. We asked whether alterations in Eph receptors could underlie cognitive impairment in an AD mouse model overexpressing human amyloid-beta protein precursor (hA beta PP) with familial mutations (hA beta PP swe-ind mice). We found that EphA4 and EphB2 receptors were reduced in the hippocampus before the development of impaired object recognition and spatial memory. Similar results were obtained in another line of transgenic A beta PP mice, Tg2576. A reduction in Eph receptor levels was also found in postmortem hippocampal tissue from patients with incipient AD. At the time of onset of memory decline inhA beta PP swe-ind mice, no change in surface expression of AMPA or NMDA receptor subunits was apparent, but we found changes in Eph-receptor downstream signaling, in particular a decrease in membrane-associated phosho-cofilin levels that may cause cytoskeletal changes and disrupted synaptic activity. Consistent with this finding, Eph receptor activation in cell culture increased phosho-cofilin levels. The results suggest that alterations in Eph receptors may play a role in synaptic dysfunction in the hippocampus leading to cognitive impairment in a model of AD.
Mitigating Soil-Side Corrosion on Crude Oil Tank Bottoms Using Volatile Corrosion Inhibitors (2013)

Abstract Soil-side corrosion of the bottom plates of above ground crude oil storage tanks is a major corrosion challenge in the oil and gas industry, especially when these tanks are constructed on oiled-sand pads. Severe corrosion has been identified on tank bottoms at a crude oil tank farm in the Arabian Peninsula. Corrosion led to the costly replacement of bottom plates. The soil-side surfaces of the bottom plates were designed to be protected by a shallow anode impressed current cathodic protection (CP) system. The oily sand layer and air gaps under the bottom plates reduced CP effectiveness and resulted in severe corrosion. To reduce corrosion damage, volatile corrosion inhibitor (VCI) was injected into the air gap between the sand pad and the underside of the tank bottom during a scheduled maintenance outage. An electrical resistance (ER) probe corrosion monitoring system was also installed underneath the tank. Effectiveness of the VCI treatment was monitored using the ER probe system. Corrosion rate data from ER probes indicated that VCIs were effective in mitigating corrosion on carbon steel bottom plates during the first year after application. Extended monitoring will continue in subsequent years and be the subject of future papers. VCI technology has good potential to reduce crude tank bottom corrosion, reduce maintenance costs, and provide extended service life.
China at the World Council (1921)

Essay| December 01 1921 China at the World Council Sao-Ke Alfred Sze Sao-Ke Alfred Sze Minister of China to the United States and Ambassador Plenipotentiary to the Washington Conference Search for other works by this author on: This Site PubMed Google Scholar Current History (1921) 15 (3): 397–399. https://doi.org/10.1525/curh.1921.15.3.397 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Sao-Ke Alfred Sze; China at the World Council. Current History 1 December 1921; 15 (3): 397–399. doi: https://doi.org/10.1525/curh.1921.15.3.397 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentCurrent History Search This content is only available via PDF. © 1921 by The Regents of the University of California1921 Article PDF first page preview Close Modal You do not currently have access to this content.
<title>Novel integrated optical sensor for DNA arrays detection</title> (2000)

A novel integrated optical biosensor, that combines optical planar waveguides for illumination with microlens arrays for collection of fluorescence, is presented in this paper. This sensor is based on laser induced fluorescence detection and will be applied for biochemical or chemical applications such as fluorescence labeled DNA affinity assay. An evanescent field is generated by the optical planar waveguides, which illuminate DNA arrays on the surface of the waveguide. High signal to noise ratio and sensitivity can be achieved since the evanescent field is tightly confined within the neighborhood of the surface of waveguides and laser noise will scarcely reach the detector. Micro lens arrays with large numerous aperture are combined into the sensor to collect more fluorescent lights from DNA samples induced by the evanescent field. A high sensitive CCD is used for this multi-channel system. The sensor has advantages of compactness, multi-dimensional channel detection simultaneously, high sensitivity and good compatibility with biology samples, so it is not only suitable to be used in detection of fluorescent labeled DNA arrays, but also can be used in other life science research like fluorescence immunoassays. The compact design of the sensor allows it to be integrated in a micro total analysis system ((mu) -TAS) such as a portable DNA diagnostics device.
An Anatomically Customizable Computational Model Relating the Visual Field to the Optic Nerve Head in Individual Eyes (2012)

Relations between ONH sectors and many VF locations are strongly anatomy-dependent. Our model may be used to produce customized maps from VF locations to the ONH in individual eyes where some simple biometric parameters are known.
Biological Activities of a New Steroidal Inhibitor of  4-5 -Reductase (1982)

17β-N,N-Diethylcarbamoyl-4-methyl-4-aza-5α-androstan-3-one (4-MA), a known 5α-reductase inhibitor, was tested in a variety of bioassays designed to document its endocrinological spectrum. It proved to be a relatively nontoxic compound which showed little or no antifertility activity in either male or female rats, no significant estrogenic, progestational, androgenic, or gonadotropin-inhibiting potency, and it did not affect serum prolactin levels. 4-MA did, however, cause feminization of male fetuses carried by treated pregnant female rats. It also caused a cessation in growth of the ventral prostate and seminal vesicles of young adult male rats. Both the feminization of male fetuses and the inhibition of male sex accessory growth are believed to be a result of the inhibition of 5α-reductase by 4-MA.
Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. (1986)

mRNA coding for the catalytic (C) subunit of cAMP-dependent protein kinase (ATP: protein phosphotransferase, EC 2.7.1.37) was partially purified from bovine testis by polysome immunoadsorption and oligo(dT)-chromatography. This enriched mRNA preparation was used to prepare and differentially screen a cDNA library. One of the selected cDNA clones was shown to hybrid-select mRNA coding for a 40-kDa protein that was specifically precipitated with antibodies to the C subunit. This bovine cDNA clone was then used to isolate a series of mouse cDNA clones that are complementary to the entire mouse C subunit mRNA. The mouse clones code for a protein of 351 amino acids that shows 98% homology to the bovine C subunit and hybridize to a single mRNA of 2.4 kilobases in mouse heart and brain. Southern blot analysis of total genomic DNA suggests that there is a single mouse gene coding for the C subunit. mRNA levels for both the C subunit and the type I regulatory subunit in various mouse tissues and cell lines were quantitated and compared by using single-stranded RNA probes prepared with SP6 polymerase.
Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes (1966)

Abstract Streptomycin-sensitive 70S ribosomes which are dissociated into 50S and 30S particles by dialysis against 1 x 10-4 m magnesium acetate, and then reassociated in 0.02 m magnesium acetate, differ from nondissociated 70S ribosomes in 14C-aminoacyl soluble ribonucleic acid (sRNA) binding. 1. Reassociated ribosomes bind about twice as much 14C-phenylalanyl-sRNA in the presence of polyuridylic acid as nondissociated ribosomes. 2. 14C-Phenylalanyl-sRNA binding to reassociated ribosomes in the presence of polyuridylic acid is reduced 50% by streptomycin; this binding to nondissociated ribosomes is only slightly affected by streptomycin. 3. Streptomycin can inhibit 14C-isoleucyl-sRNA binding to reassociated ribosomes in the presence of polyuridylic acid, but stimulates this binding to nondissociated ribosomes. These effects are greatly influenced by the sRNA-ribosome ratio. Shearing 70S ribosomes by passage through a micropipette also produces Reactions 2 and 3 above, but not Reaction 1. The results indicate that various treatments of the ribosomes (dissociation, shearing) and sRNA to ribosome ratios modify the effects of streptomycin on 14C-aminoacyl-sRNA binding to ribosomes. In addition, the data suggest that different mechanisms may be involved in the effects of streptomycin on inhibiting protein synthesis and on stimulating ambiguous codon recognitions.
Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7 (2003)

E1B-AP5 was initially identified as a target of the early adenovirus E1B-55 kDa protein during the course of lytic infection. E1B-AP5 belongs to the heterogeneous nuclear ribonucleoprotein family and was demonstrated to be involved in mRNA processing and transport [Gabler, Schutt, Groitl, Wolf, Shenk and Dobner (1998) J. Virol. 72, 7960-7971]. In the present paper, we demonstrate that E1B-AP5 differentially regulates basic and ligand-dependent transcription. We found that E1B-AP5 represses basic transcription driven by several virus and cellular promoters, and mapped the repression activity to the N-terminal part of the protein. In contrast with basic repression, E1B-AP5 activated the glucocorticoid-dependent promoter in the absence of dexamethasone, but did not contribute to the dexamethasone-induced activation. Mutant analysis indicated the presence of an additional cellular factor that modulates E1B-AP5 transcriptional activity. Using yeast two-hybrid screening, we identified a novel chromatin-associated bromodomain-containing protein, BRD7, as an E1B-AP5 interaction partner. We confirmed E1B-AP5-BRD7 complex formation in vivo and in vitro. We found that, although BRD7 binds to histones H2A, H2B, H3 and H4 through its bromodomain, this domain was not necessary for the interaction with E1B-AP5. Indeed, the triple complex formation of E1B-AP5, BRD7 and histones was demonstrated. Disruption of the E1B-AP5-BRD7 complex increased E1B-AP5 repression activity for basic transcription and converted it from being an activator of the hormone-dependent promoter into being a strong repressor. We conclude that complex formation between BRD7 and E1B-AP5 links chromatin events with mRNA processing at the level of transcriptional regulation.
Ranking with Recursive Neural Networks and Its Application to Multi-Document Summarization (2015)

We develop a Ranking framework upon Recursive Neural Networks (R2N2) to rank sentences for multi-document summarization. It formulates the sentence ranking task as a hierarchical regression process, which simultaneously measures the salience of a sentence and its constituents (e.g., phrases) in the parsing tree. This enables us to draw on word-level to sentence-level supervisions derived from reference summaries.In addition, recursive neural networks are used to automatically learn ranking features over the tree, with hand-crafted feature vectors of words as inputs. Hierarchical regressions are then conducted with learned features concatenating raw features.Ranking scores of sentences and words are utilized to effectively select informative and non-redundant sentences to generate summaries.Experiments on the DUC 2001, 2002 and 2004 multi-document summarization datasets show that R2N2 outperforms state-of-the-art extractive summarization approaches.
A spin-labeled hapten. (1965)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Stereoselective Synthesis of γ-Substituted (<i>Z</i>)-Allylic Boranes via Kinetically Controlled Hydroboration of Allenes with 10-TMS-9-borabicyclo[3.3.2]decane (2009)

Kinetically controlled hydroboration of allenes 8 and 14a-d with the readily accessible Soderquist borane 7, which is generated in situ from borohydride 6, constitutes a convenient and preparatively useful method for synthesis of (Z)-gamma-(substituted)allylboranes 9 and 15a-d. These allylboranes undergo highly diastereo- (> or = 90: 10) and enantioselective (typically 89-96% e.e.) allylboration reactions with representative aldehydes to give syn-beta-functionalized homoallylic alcohols.
Enesulfonamides as Nucleophiles in Catalytic Asymmetric Reactions (2007)

A biased copper-coin toss: Highly diastereo- and enantioselective copper-catalyzed addition reactions of enesulfonamides to α-keto aldehydes and azodicarboxylates have been developed. Low loadings of the chiral copper catalyst efficiently promoted the reaction (see scheme). The product sulfonylimines could be reduced diastereoselectively to the biologically important chiral sulfonamide compounds. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z605054_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
TOBRAMYCIN SERUM CONCENTRATIONS AFTER AEROSOL AND ORAL ADMINISTRATION IN CYSTIC FIBROSIS (1995)

We sought to describe tobramycin absorption after aerosol administration to cystic fibrosis (CF) subjects. Serum tobramycin concentrations were determined by modification of the radioimmuno-assay (RIA) technique, lowering the limit of detection from 1.0 &mgr;g ml(minus sign1) to 0.05 &mgr;g ml(minus sign1). In 37 studies, after aerosol delivery of 666 plus minus 195 mg to the airway of 24 patients, in which 222 samples were assayed, only 1 serum sample contained tobramycin at a concentration greater than 1.0 &mgr;g ml(minus sign1). Twenty-six of the 37 studies permitted estimation of pharmacokinetic parameters of tobramycin. The serum clearance of tobramycin following aerosol adminstration is 39.13 plus minus 0.393 L h(minus sign1) (mean plus minus standard error of the mean), with an elimination half-life of 3.072 plus minus 0.194 h. The half-life was significantly longer than that found after intravenous adminstration. The elimination rate constant (K(e)) was calculated to be 0.234 plus minus 0.002 h(minus sign1). Estimated total-body clearance in which systemic absorption was determined from sputum and urinary recovery of tobramycin was 0.094 plus minus 0.002 1 hr(minus sign1) kg(minus sign1). We also studied tobramycin absorption in six CF subjects after ingestion of a 80-mg m(minus sign2) dose, to gain insight into the tobramycin levels observed after swallowing an aerosol. Four out of the six subjects had measurable serum tobramycin concentration after ingestion. The serum concentration-time curve mirrored what was seen after aerosol administration. We concluded that tobramycin has poor systemic absorption in CF subjects after aerosol administration. Tobramycin in serum after aerosol administration is in part due to the gastrointestinal absorption of swallowed drug, as well as absorption from lower respiratory tract.
A new technique to reproduced High-Dynamic-Range images for Low-Dynamic-Range display (2011)

Tone mapping is a process for reproduction of High-Dynamic-Range images (HDR) for Low-Dynamic-Range (LDR) output devices. In this report, author presents a new local tone-mapping operator, derived from the Contrast Limited Adaptive histogram Equalization (CLAHE) technique for displaying high dynamic range image. The CLAHE is a method which was originally developed for medical imaging. This method has effectively expanded the full dynamic range of display and it is fully automatic. Due to different luminance intervals could result in overlapped reaction on the limited response in limited response range of visual system, scene region splitting and merging were used to segment the scaled luminance and perform the image segmentation to segment image into smaller part. After the region splitting and merging, there will be some noise or variation of intensity that may result in holes or over segmentation. As the result, the morphological operation, opening and closing were used to perform the mask to applied different clip limit of the CLAHE operation.
P-i-n diodes enabled by homoepitaxially grown phosphorus doped diamond with breakdown electric field &#x003E;1.25 MV/cm (2015)

Owing to its rich material properties, such as high critical electric field, superior thermal conductivity and high electron and hole mobility, diamond has the potential of becoming the material of choice for high power electronic applications. In spite of superior bulk electrical and thermal properties, the only well-known use of diamond in power electronics has been as a heat sink. This is because of the lack of good quality homoepitaxially grown n-type diamond and also the difficulty involved in achieving ohmic contacts due to its very low-work function ( 0.9 eV). Although several approaches have been explored to obtain highly doped n-type diamond very few have been successful. In this presentation we report the successful fabrication and characterization of a p-i-n diode enabled by the development of low-resistance contacts to n-type diamond using Ti/Pt/Au metal contacts. This was made possible by a novel growth scheme where highly P-doped homoepitaxial diamond could be grown consistently.
Posterior cingulate epilepsy: clinical and neurophysiological analysis (2013)

This study revealed that the network from the posterior cingulate gyrus and the semiology of PCE (motor manifestation vs dialeptic/automotor seizure) varies depending upon the seizure spread patterns.