gebhart/patrepeval huggingface dataset:
Rapid determination of acetone in human blood by derivatization with pentafluorobenzyl hydroxylamine followed by headspace liquid‐phase microextraction and gas chromatography/mass spectrometry (2005)

In the current work, a simple, rapid, accurate and inexpensive method was developed for the determination of acetone in human blood. The proposed method is based on derivatization with O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA), followed by headspace liquid-phase microextraction (HS-LPME) and gas chromatography/mass spectrometry (GC/MS). In the present method, acetone in blood samples was derivatized with PFBHA and acetone oxime formed in several seconds. The formed oxime was enriched by HS-LPME using the organic solvent film (OSF) formed in a microsyringe barrel as extraction interface. Finally, the enriched oxime was analyzed by GC/MS in electron ionization (EI) mode. HS-LPME parameters including solvent, syringe plunger withdrawal rate, sampling volume, and extraction cycle were optimized and the method reproducibility, linearity, recovery and detection limit were studied. The proposed method was applied to determination of acetone in diabetes blood and normal blood. It has been shown that derivatization with HS-LPME and GC/MS is an alternative method for determination of the diabetes biomarker, acetone, in blood samples.
The Tetranychid mites of Tasmania (1966)

Formerly only four species of the family Tetranychidae had been recorded from Tasmania. Collections of mites from both introduced and native plants have revealed that the family is represented by ten genera of which two are new. Fifteen species, five being new, are now recorded from the State. The following new genera and species are described:- New genera-Synonychus, Tylonychus. New species-Synonychus eucalypti, Eutetranychus acaciae, Tylonychus tasmaniensis, Eotetranychus hudsoni and Tetranychus rhagodiae. In addition the male of Schizonobia sycophanta Wom. is described for the first time.
Étude de la formation de polyantimonates en milieu faiblement acide (1974)

L’acidification partielle [(H3O+)/Sb = 0,7] d’une solution d’antimonate de tétraméthylammonium conduit à terme à des composés hautement polymérisés proches de l’acide antimonique [math] renfermant une proportion importante d’ions tétraméthylammonium. Bien que dès l’acidification il ne reste pas d’ions monomères [Sb(OH)6]-, après une évolution très longue via différentes espèces condensées peu réactives, il est remarquable de voir se former une petite proportion d’ions monomères [Sb(OH)6]-.
Crizotinib in ALK-Positive Diffuse Large B-Cell Lymphoma: A Case Report (2012)

Abstract Abstract 4862 Background: Anaplastic lymphoma kinase (ALK)-positive diffuse large B-cell lymphoma (DLBCL) displays a rare and distinct variant of DLBCL characterized by very aggressive clinical course with an estimated median survival of only 11.0 months. Crizotinib, an ALK inhibitor, has demonstrated impressive clinical efficacy in patients with alk-rearranged tumors such as NSCLC. The potential role of Crizotinib in ALK-positive DLBCL has not been established yet. Case report: A 27-year-old female patient with initial advanced-stage IV ALK-positive DLBCL was primary refractory to 6 cycles of standard chemotherapy with CHOP. She was subsequently treated with different salvage combination chemotherapy regimens including high-dose chemotherapy with autologous stem-cell transplantation. However, disease followed a very aggressive course and relapse occurred fast after each regimen. 6 weeks after transplantation patient presented with right cervical lymphadenopathy and multiple cutaneous lesions. CT scan revealed additional bilateral cervical, axillary, mediastinal and abdominal lymphadenopathy and involvement of lung and liver. LDH levels were exorbitant elevated (233 mmol/l). On an individual base, our patient received the ALK inhibitor Crizotinib 250 mg per os twice daily. No glucocorticoids or other drugs with antineoplastic activity were co-administered. Within 72 hours LDH levels were halved (89 mmol/l). On day 8 cervical palpable lymphadenopathy disappeared. Initial erythematous papular cutaneous lesion decreased from 4.0 × 2.5 cm to a residual hyperpigmented macule of 1.5 × 2.5 cm. On day 16 LDH levels were almost within normal limits (6 mmol/l). However, remission was not sustained and patient developed resistance to Crizotinib. By day 21 after beginning the treatment with Crizotinib LDH levels increased again and patient presented with a swollen left arm due to lymphatic obstruction, detected by CT scan, which showed a general progressive disease, causing death one month later. Conclusion: To our knowledge, this is the first case which reports sensitivity in ALK-positive DLBCL to ALK inhibition with Crizotinib. Despite remission duration was short our results indicate a potential role of ALK in the pathogenesis of ALK-positive DLBCL and suggest ALK inhibition as a potentially promising treatment modality in the therapy of this rare and fatal disease. Disclosures: Off Label Use: Crizotinib is an ALK inhibitor, indicated for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (ALK)-positive. Recently impressive clinical efficacy of Crizotinib has been reported in two patients with ALK-positive anaplastic large cell lymphoma. Based on these data we initiated the treatment with Crizotinib in our patient, who showed very aggressive clinical behavior and fulminant early recurrence of a ALK-positive diffuse large B-cell lymphoma after salvage chemotherapy regimens on an individual base.
Note. Xylose Production from Durum Wheat Bran: Enzymic versus Chemical Methods (2004)

Both acidic and enzymic hydrolytic processes of durum wheat bran to obtain high xylose syrups are discussed in terms of yields and operative conditions. Mild sulphuric hydrolysis gave the best results (400mg of aldopentoses per gram of pre-extracted wheat bran within 4–6 h) whereas hydrochloric and especially phosphoric acids led to low yields. Preliminary work with a highly active recombinant xylanase (endoxylanase) led to deep solubilisation of arabinoxylans, mainly leading to oligosaccharides and their acyl (essentially feruloyl) derivatives. Mild sulphuric hydrolysis still seems to be the treatment of choice for xylose recovery from durum wheat bran.
Comparison of Two Blood Pool Contrast Agents for 0.5-T MR Angiography: Experimental Study in Rabbits (2000)

Both blood pool agents were found to be promising contrast agents for 0.5-T MR angiography; however, their clinical applicability warrants further investigation. The gadolinium-based agent had several advantages over the iron oxide compound, including less T2* dephasing, lack of susceptibility artifacts, and fast renal elimination.
The Accuracy Requirements in Fifth Place Refractometry (1939)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text H. W. Straat and J. W. Forrest, "The Accuracy Requirements in Fifth Place Refractometry," J. Opt. Soc. Am. 29, 240-247 (1939) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Automatic construction of 3D human face models based on 2D images (2002)

In order to achieve low bit-rate video coding, model-based coding systems have attracted great interests in visual telecommunications, e.g., videophone and teleconferencing where the human faces are the major part in the scenes. The main idea of this approach is to construct a 3D model for human face. Only the moving parts on the face are analyzed and the motion parameters are transmitted, finally the original facial expressions could be synthesized by deforming the face model using the facial motion parameters. We propose an approach to the automatic construction of 3D human face models using a generic face model and several 2D face images. A template matching based algorithm is developed to automatically extract all necessary facial features from the front and side profile face images. Then the generic face model is fitted to these feature points by geometric transforms. Finally, texture mapping is performed to achieve realistic results.
A Simple Way to Estimate the Cost of Downtime (2002)

Granulomatous orbital inflammation without any local cause or other systemic granulomatous disease strongly suggests a systemic sarcoidosis. In case of missing lymph node enlargement in conventional chest X-ray computertomography should be performed.
Production of Monoclonal Antibodies Reacting with Rat Islet Cell Membrane Antigens (1981)

The present communication describes the generation of twelve lymphocyte hybrid cell lines whose antibodies react with the rat islet cell line RIN, and the initial characterization of the tissue specificity and functional properties of these antibodies. Since antibodies recognizing islet cell differentiation antigens were sought, these permanent hybrid cell lines were developed from cultures whose antibodies, by radioimmunoassay, bound minimally or not at all to rat red blood cells (cell line A3C1 is an exception). Antibodies from five of the cell lines by radioimmunoassay react significantly with cultured rat fibroblasts in addition to their reaction with RIN cells. Antibody F41-5D6 by indirect immunofluorescence reacted with sections of the RISL transplantable islet cell tumor and specifically with islet cells in sections of rat pancreas. Four antibodies (F41-1G3, 5B5, 6C5, and 5A5), by indirect immunofluorescence, reacted with sections of the RISL transplantable islet cell tumor but not with sections of normal pancreas. Seven of the antibodies were cytotoxic to cultured RIN cells and seven antibodies share the useful property of reacting with protein A. This study demonstrates the feasibility of producing monoclonal antibodies to islet cell differentiation antigens and describes several antibodies which should be useful reagents in studies of the physiology and pathophysiology of the islet cell plasma membrane.
New design of single-bit all-digital RSFQ autocorrelator (1997)

We present a new design of a Rapid Single-Flux-Quantum (RSFQ) all-digital one-bit autocorrelator for submillimeter spectrometry applications, featuring 4 GHz input signal bandwidth, double oversampling quantizer, and 16 Mbps-per-channel output rate. The delay line of the autocorrelator is based on a circular shift register with XOR gates performing multiplication of the delayed and undelayed single-bit signals at every stage. The multiplication results are accumulated by room-temperature electronics after being prescaled in on-chip binary counters consisting of 10 T flip-flops per stage. We report results of experimental testing of a 16-stage autocorrelator delay line with multiplication and for a linear array of 8 low-power T flip-flop binary counters, all fabricated in HYPRES' standard 3.5 /spl mu/m 1000 A/cm/sup 2/ Nb-trilayer process. We also discuss physical and technical limits of the minimal power dissipation in RSFQ circuits.
Amphiphilic Polymethacrylate Model Co-Networks:  Synthesis by RAFT Radical Polymerization and Characterization of the Swelling Behavior (2006)

Reversible addition−fragmentation chain transfer (RAFT) controlled radical polymerization was employed, for the first time, to prepare well-defined (model) amphiphilic polymer co-networks based on n-butyl methacrylate (BuMA, hydrophobic monomer) and 2-(dimethylamino)ethyl methacrylate (DMAEMA, hydrophilic ionizable monomer) cross-linked with ethylene glycol dimethacrylate (EGDMA) and bearing elastic chains having the following comonomer distributions: BuMA-b-DMAEMA-b-BuMA and DMAEMA-b-BuMA-b-DMAEMA triblock and BuMA-co-DMAEMA statistical copolymers. Two randomly cross-linked (not model) amphiphilic co-networks were also synthesized, the one by RAFT and the other by conventional free radical polymerization. The amphiphilic triblock copolymer-based model co-networks were obtained by stepwise synthesis in three stages: (1) the synthesis of linear homopolymers bearing two active ends by using a bifunctional chain transfer agent (CTA), (2) the sequential addition of the second monomer on the macro-CTAs (homopolymers) to yield linear ABA or BAB triblock copolymers, and (3) the inter-linking of the linear copolymer chains at both ends using EGDMA cross-linker to form the final model co-networks. The homopolymer and copolymer precursors to the networks were characterized using gel permeation chromatography and 1H NMR spectroscopy. The swelling behavior of the networks was investigated in tetrahydrofuran and water. The co-networks swelled more in acidic than in neutral water due to the ionization of their DMAEMA units. The low pH aqueous swelling of the statistical co-network was higher than those of its triblock counterparts due to the lack of microphase separation with the statistical copolymer chains.
Autonomous micro-sensor arrays for process control of semiconductor manufacturing processes (2003)

We first motivate the use of autonomous micro-sensor arrays for use in semiconductor manufacturing. Following this, we discuss three critical issues that must be addressed in order to realize our goal of building these micro-sensor arrays. We then describe our on-going development-efforts of fabricating spatially resolved etch-rate and temperature sensors.
A comparison of message passing and shared memory architectures for data parallel programs (1994)

Shared memory and message passing are two opposing communication models for parallel multicomputer architectures. Comparing such architectures has been difficult, because applications must be hand-crafted for each architecture, often resulting in radically different sources for comparison. While it is clear that shared memory machines are currently easier to program, in the future, programs will be written in high-level languages and compiled to the specific parallel target, thus eliminating this difference.In this paper, we evaluate several parallel architecture alternatives --- message passing, NUMA, and cachecoherent shared memory --- for a collection of scientific benchmarks written in C*, a data-parallel language. Using a single suite of C* source programs, we compile each benchmark and simulate the interconnect for the alternative models. Our objective is to examine underlying, technology-independent costs inherent in each alternative. Our results show the relative work required to execute these data parallel programs on the different architectures, and point out where some models have inherent advantages for particular data-parallel program styles.
Perception of facial expression and facial identity in subjects with social developmental disorders (2005)

The processing of facial identity and that of facial expression are dissociable in social developmental disorders. Deficits in perceiving facial expression may be related to emotional processing more than face processing. Dissociations between the perception of facial identity and facial emotion are consistent with current cognitive models of face processing. The results argue against hypotheses that the social dysfunction in social developmental disorder causes a generalized failure to acquire face-processing skills.
[IgA and its different molecular forms in the mesenteric, portal and peripheral venous blood in man]. (1986)

The aim of this study was to assess the role of mesenteric blood in polymeric IgA (p-IgA) and IgA2-transport from the intestinal mucosa into plasma and the role of the liver in the clearance of these molecular forms of IgA. The concentrations of IgA, p-IgA and IgA2 were measured in mesenteric, splenic, portal, and hepatic veins of 7 control subjects without liver disease and in portal and peripheral veins of 4 patients with alcoholic cirrhosis. In control subjects, the concentration of the different molecular forms of IgA were not significantly different in mesenteric and in splenic vein. No significant decrease of IgA concentrations was observed in hepatic vein, as compared with portal vein. In cirrhotic patients IgA concentrations were significantly higher than in control subjects, but concentrations of IgA, p-IgA and IgA2 were not different in portal and peripheral blood. These results show that mesenteric vein is not a major way for p-IgA and IgA2 from the gut lamina propria to plasma, and suggest that the origin of a significant part of these molecular forms of IgA could be peripheral lymph-nodes more than gut-associated-lymphoid-tissue. The absence of significant clearance of p-IgA by the liver in normal subjects suggests that abnormalities of hepato-biliary transport of p-IgA is not responsible for the increased IgA levels observed in cirrhotic patients.
Dinucleoside Phosphates Containing Arabinose or Deoxyxylose. Hydrolysis by Exonucleases and Stacking Properties (1990)

Abstract Two pairs of isomeric dinucleoside monophosphates containing either 1-β-D-arabinofuranosyl)uracil (arabino-U, aU) or 1-β3-D-2-deoxy-threo-pentofuranosyl) thymine (2′-deoxyxylo-T, dxT) were synthesized. The kinetics of the hydrolysis of these dimers by venom and spleen phosphodiesterases (PDE) were studied. In addition, circular dichroism was used to study their stacking behaviour. A correlation was found to exist between the enzymatic cleavage rate and the conformation of the dimers. It was found that the configuration change at C-2′ or C-3′ in the 5′-terminal nucleoside residue, especially the inversion of 3′-hydroxyl involved into the internucleotide 3′-5′-phosphodiester linkage formation, was critical.
Two-dimensional bi-periodic grating coupled one- and two-color quantum well infrared photodetectors (1995)

Multiple quantum well infrared photodetectors (QWIP's) with two-dimensional bi-periodic grating couplers have been demonstrated. For one-color QWIP's, the response linewidths of such QWIP's are found to be much wider than those of conventional grating coupled QWIP's. The bi-periodic gratings have also been applied to two-color QWIP's to separately optimize the absorption at two wavelength bands. The large difference in responsivities at the two wavelength bands for devices with single period gratings can be greatly reduced with the use of bi-periodic gratings.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Studies of Regulation of Gastrin Synthesis and Post‐translational Processing by Molecular Biology Approaches<sup>a</sup> (1990)

We have examined the regulation of gene expression and post-translational processing of progastrin by starvation and feeding in rats. An oligonucleotide complementary to rat preprogastrin cDNA was used in RNA blot and hybridization analysis to measure gastrin mRNA levels. A region-specific antibody raised against the predicted amino acid sequence of the carboxyl terminal extension of progastrin was used for quantitation of progastrin peptides. The effects of starvation and of refeeding on rat antral gastrin mRNA and pro-hormone peptide levels were examined in rats starved for 48 h and after refeeding with a solid meal. Antral gastrin mRNA concentrations decreased to a plateau level (30% of the nonstarved control) after 48 h of starvation. Immunoreactive gastrin concentration decreased threefold, but progastrin processing intermediates did not decrease significantly during fasting. Following refeeding, significant increases in antral mRNA level were detected in 1 h, and peak levels were reached by 2 h (more than two times higher than starved control). There was a rapid and significant decrease in progastrin immunoreactivity within 30 min, followed by a significant increase in gastrin immunoreactivity 2 h after refeeding. These data suggest that rapid increases of blood and tissue gastrin levels in response to food may be associated with increases in both gastrin gene expression and post-translational processing of progastrin.
Synthesis and characterization of temperature‐sensitive block copolymers from poly(<i>N</i>‐isopropylacrylamide) and 4‐methyl‐ε‐caprolactone or 4‐phenyl‐ε‐caprolactone (2010)

Abstract This study synthesizes thermally sensitive block copolymers poly( N ‐isopropylacrylamide)‐ b ‐poly(4‐methyl‐ε‐caprolactone) (PNIPA‐ b ‐PMCL) and poly( N ‐isopropylacrylamide)‐ b ‐poly(4‐phenyl‐ε‐caprolactone) (PNIPA‐ b ‐PBCL) by ring‐opening polymerization of 4‐methyl‐ε‐caprolactone (MCL) or 4‐phenyl‐ε‐caprolactone (BCL) initiated from hydroxy‐terminated poly( N ‐isopropylacrylamide) (PNIPA) as the macroinitiator in the presence of SnOct 2 as the catalyst. This research prepares a PNIPA bearing a single terminal hydroxyl group by telomerization using 2‐hydroxyethanethiol (ME) as a chain‐transfer agent. These copolymers are characterized by differential scanning calorimetry (DSC), 1 H‐NMR, FTIR, and gel permeation chromatography (GPC). The thermal properties ( T g ) of diblock copolymers depend on polymer compositions. Incorporating larger amount of MCL or BCL into the macromolecular backbone decreases T g . Their solutions show transparent below a lower critical solution temperature (LCST) and opaque above the LCST. LCST values for the PNIPA‐ b ‐PMCL aqueous solution were observed to shift to lower temperature than that for PNIPA homopolymers. This work investigates their micellar characteristics in the aqueous phase by fluorescence spectroscopy, transmission electron microscopy (TEM), and dynamic light scattering (DLS). The block copolymers formed micelles in the aqueous phase with critical micelle concentrations (CMCs) in the range of 0.29–2.74 mg L −1 , depending on polymer compositions, which dramatically affect micelle shape. Drug entrapment efficiency and drug loading content of micelles depend on block polymer compositions. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Reduced Compressibility and an Inverse Problem for a Spinning Gas (2013)

A spinning ideal gas in a cylinder with a smooth surface is shown to have unusual properties. First, under compression parallel to the axis of rotation, the spinning gas exhibits reduced compressibility because energy can be stored in the rotation. Second, the spinning breaks the symmetry under which partial pressures of a mixture of gases simply add proportional to the constituent number densities. Thus, remarkably, in a mixture of spinning gases, an inverse problem can be formulated such that the gas constituents can be determined through external measurements only.
Interfacial reactions between lead-free SnAgCu solder and Ni(P) surface finish on printed circuit boards (2002)

Transmission electron microscopy and scanning electron microscopy were employed to analyze the interfacial microstructure between Sn-Ag-Cu solder alloys and Ni(P)/Au metallizations. The intermetallic compound Cu/sub 6/Sn/sub 5/, containing a small amount of dissolved Ni, was found to form preferentially on the Ni coating. This compound layer served as a barrier for direct reaction of Sn with the Ni(P) coating. On the Ni(P) side, a nickel phosphide was identified. Thermodynamic evaluation of the Cu-Ni-Sn system was carried out to rationalize the enrichment of Cu at the solder/finish interface. Effects of the interfacial reactions on joint reliability are discussed.