gebhart/patrepeval huggingface dataset:
MIMO Self-Interference Mitigation Effects on Power Line Relay Networks (2011)

Power Line Communications (PLCs) enable new and highly convenient networking functions in the framework of Smart-Grids and use an already built-in network. A Multiple Input Multiple Output (MIMO) architecture can strongly improve the PLC performances and links' reliability. In this contribution the effect of self-interference generated by relay nodes has been considered and the MIMO potentials for spatial multiplexing and interference suppression have been taken into account. The importance of channel knowledge has been also considered from a numerical result point of view in order to give some instruments for network planning.
ArchShield (2013)

DRAM scaling has been the prime driver for increasing the capacity of main memory system over the past three decades. Unfortunately, scaling DRAM to smaller technology nodes has become challenging due to the inherent difficulty in designing smaller geometries, coupled with the problems of device variation and leakage. Future DRAM devices are likely to experience significantly high error-rates. Techniques that can tolerate errors efficiently can enable DRAM to scale to smaller technology nodes. However, existing techniques such as row/column sparing and ECC become prohibitive at high error-rates. To develop cost-effective solutions for tolerating high error-rates, this paper advocates a cross-layer approach. Rather than hiding the faulty cell information within the DRAM chips, we expose it to the architectural level. We propose ArchShield , an architectural framework that employs runtime testing to identify faulty DRAM cells. ArchShield tolerates these faults using two components, a Fault Map that keeps information about faulty words in a cache line, and Selective Word-Level Replication (SWLR) that replicates faulty words for error resilience. Both Fault Map and SWLR are integrated in reserved area in DRAM memory. Our evaluations with 8GB DRAM DIMM show that ArchShield can efficiently tolerate error-rates as higher as 10 −4 (100x higher than ECC alone), causes less than 2% performance degradation, and still maintains 1-bit error tolerance against soft errors.
Bentiromide Test Is Not Affected in Patients with Small Bowel Disease or Liver Disease (1987)

The bentiromide test reliably detects exocrine pancreatic insufficiency. The synthetic peptide attached to p-aminobenzoic acid (PABA) is cleaved by chymotrypsin, PABA is absorbed in the small intestine, partially conjugated in the liver, and excreted in the urine. It has been claimed that the bentiromide test is abnormal not only in patients with pancreatic insufficiency but also in patients with small bowel or liver disease because of impaired PABA absorption or conjugation, respectively. This study prospectively evaluates the bentiromide test in 12 patients with small bowel disease and 18 patients with biopsy-proven liver disease. One of 30 patients had an abnormal bentiromide test. Cumulative 6-h urinary arylamine excretion and plasma PABA concentration, 2 h after administration, were in the same range as healthy controls. We conclude that the bentiromide test is not affected by small bowel or liver disease. An abnormal test is virtually diagnostic for exocrine pancreatic insufficiency.
Power Supply for Medical Implants by Wiegand Pulse Generated from Magnetic Wire (2018)

Implantable medical devices are utilized in the human body for maintaining good health. As these devices are becoming increasingly functionalized, supplying power to them has become very important. Instead of batteries, technologies for wireless power supplies are being developed, such as inductive coupling or piezoelectric elements. However, we propose the use of magnetic wires for this purpose. Inside these wires, a fast magnetization reversal, called a "large Barkhausen jump," occurs due to an applied magnetic field. This reversal induces a large pulse voltage in pick-up coils, which is called a "Wiegand pulse." By applying this pulse as an electric source, a higher electric power is expected compared with the conventional method using a sinusoidal excitation field. A wire core coil was prepared, and open-circuit voltage was measured. In addition, DC voltage and electric power were measured by connecting the wire core coil to a rectifier. The experimental results confirmed the superiority of using a Wiegand pulse at an applied magnetic field intensity of 60 Oe and a frequency of lower than 10 kHz.
PMD-Supported Coherent Optical OFDM Systems (2007)

Although polarization-mode dispersion (PMD) greatly impairs conventional high-speed single-carrier systems, it is shown that for multicarrier systems such as coherent optical orthogonal frequency-division-multiplexed systems (CO-OFDM), not only does PMD not cause any impairment, but it also provides a benefit of polarization diversity against polarization-dependent-loss-induced fading and consequently improves the system margin. The PMD benefit to fiber nonlinearity reduction in CO-OFDM systems is also predicted
Optimization of VCSEL with an integrated resonant photodetector (2002)

We show that the intracavity detector-VCSEL performance depends critically on the relative alignment of the Fabry-Perot wavelength and the quantum-well absorber band edge. By strategic design, we obtain well-matched behavior of the internal and external detectors-up to 5 times threshold. Comprehensive modeling agrees with experimental results.
Overproduction of YjbB reduces the level of polyphosphate in Escherichia coli : a hypothetical role of YjbB in phosphate export and polyphosphate accumulation (2011)

Intracellular phosphate (P(i) ) is normally maintained at a fairly constant concentration in Escherichia coli, mainly by P(i) transport systems and by the 'phosphate balance' between P(i) and polyphosphate (polyP). We have reported previously that excess uptake of P(i) in a phoU mutant results in elevated levels of polyP. Here, we found that the elevated levels of polyP in the mutant could be reduced by the overproduction of YjbB, whose N-terminal half contains Na(+) /P(i) cotransporter domains. The rate of P(i) export increased when the YjbB overproducer grew on a medium containing glycerol-3-phosphate. These results strongly suggested that YjbB reduced the elevated levels of polyP in the phoU mutant by exporting intracellular excess P(i) .
High-Dose Radioimmunotherapy Combined with Fixed, Low-Dose Paclitaxel in Metastatic Prostate and Breast Cancer by Using a MUC-1 Monoclonal Antibody, m170, Linked to Indium-111/Yttrium-90 via a Cathepsin Cleavable Linker with Cyclosporine to Prevent Human Anti-mouse Antibody (2005)

111In/90Y-m170 targets prostate and breast cancer and can be combined with paclitaxel with toxicity limited to marrow suppression at the dose levels above. The maximum tolerated dose of radioimmunotherapy and fixed-dose paclitaxel with peripheral blood stem cell support has not been reached. Cyclosporine is effective in preventing human anti-mouse antibody, suggesting the feasibility of multidose, "fractionated" therapy that could enhance clinical response.
Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib (2006)

Elevated levels of Src kinase expression have been found in a variety of human epithelial cancers. Most notably in colon cancer, elevated Src expression correlates with malignant potential and is also associated with metastatic disease. Dasatinib (BMS-354825) is a novel, orally active, multi-targeted kinase inhibitor that targets Src family kinases and is currently under clinical evaluation for the treatment of solid tumors. However, the effects of dasatinib on epithelial tumors are not fully understood. We show that concentrations of dasatinib that inhibit Src activity do not inhibit proliferation in 10 of 12 colon cancer cells lines. However, inhibition of integrin-dependent adhesion and migration by dasatinib correlated with inhibition of Src activity, suggesting that dasatinib may have anti-invasive or anti-metastatic activity and antiproliferative activity in epithelial tumors. Using phospho-specific antibodies, we show that inhibition of Src activity in colon cancer cell lines correlates with reduced phosphorylation of focal adhesion kinase and paxillin on specific Src-dependent phosphorylation sites. We have validated the use of phospho-specific antibodies against Src Tyr(419) and paxillin Tyr(118) as biomarkers of dasatinib activity in vivo. Colon carcinoma-bearing mice treated with dasatinib showed a decrease in both phospho-Src Tyr(419) and phospho-paxillin Tyr(118) in peripheral blood mononuclear cells, which correlated with inhibition of Src activity in the colon tumors. Thus, peripheral blood mononuclear cells may provide a useful surrogate tissue for biomarker studies with dasatinib using inhibition of Src Tyr(419) and paxillin Tyr(118) phosphorylation as read-outs of Src activity.
<i>APOE</i> ε4 allele is associated with reduced cerebrospinal fluid levels of Aβ42 (2004)

The epsilon4 allele of APOE is a risk factor for Alzheimer disease (AD). By analysis of a large cohort of AD patients (n = 563) and control subjects (n = 118), it is shown that the epsilon4 allele is strongly associated with reduced CSF levels of beta-amyloid (1-42) (Abeta42) in both AD (p < 10(-9)) and control (p = 0.0012) populations. As no associations of APOE variants with other indexes of AD severity were observed, this effect may reflect a fundamental involvement of ApoE in Abeta metabolism.
Detection of major histocompatibility complex/human cartilage gp‐39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker (2004)

Presentation by synovial dendritic cells of the immunodominant epitope of HC gp-39, in the context of the shared epitope, is associated with characteristic histologic features of follicular synovitis and is highly specific for RA. This suggests a contribution to the autoimmune-related tissue inflammation and provides a new and independent tool for the immunopathologic diagnosis of RA.
The design of a microwave plasma cavity (1974)

The design of an efficient microwave plasma source is described. This source consists of a quartz tube surrounded by a cylindrical variable-length cavity which is connected to a 2.450-GHz power microwave source. The circuit performance of the plasma-cavity system is qualitatively explained and the lossy plasma-cavity eigenfrequencies are computed as functions of plasma density, effective collision frequency, and cavity length. Experiments demonstrate that a variable high-density plasma with densities in excess of 1000 critical densities can be sustained. Furthermore, by adjusting cavity length and coupling, microwave plasmas can be sustained in flowing and nonflowing argon gaseous environments from pressures of several microns to over one atmosphere.
<title>THX 31162: 768 x 576 pixel area array CCD sensor</title> (1990)

A 2/3-inch format 768(H) x 576 (V) pixel CCD image sensor has been developed, fabricated and tested. It has a frame transfer organization and is incorporating a lateral built in anti-blooming system. A horizontal resolution of more than 500 TV lines has been obtained and photosensitivity reaches 30 mv/lux. By the possible use of two video outputs, an image mirror function is provided. Thanks to its windowing device, the sensor is well suited for tracking applications.
Application of Back-side Alignment of Thick Layers for the Manufacturing of Advanced Power Devices (2006)

Back-side alignment was implemented in the thick layer process flow for the production of advanced power devices. The alignment and overlay performance of the back-side alignment scheme are addressed, as well as the benefits in terms of productivity and cost reduction
Synthesis of Adamantane Derivatives. 39. Synthesis and Acidolysis of 2-Azidoadamantanes. A Facile Route to 4-Azahomoadamant-4-enes (1977)

2-Azidoadamantanes lob-f; and 4-azahomoadamant-4-enes lla-e were obtained in good yields on treatment M * of the corresponding alcohols 2 -L w i t h NaN3 in 5 7 % -H2S04-CH C1 and in CH SO H-CHC13, respectively.2 2 3 3 Azides 10a-e gave also lla-e on decompositions in *-/ v -CH3S03H-CHC13, while 10f afforded only adamant-,.,"vlideneaniline.We have recently reported an efficient and convenient synthesis of 1-azidoadamantane (2 and 3-hydroxy-4-azahomoadamantane (2) from 1-hydroxyadamantane (2.This procedure consists of substitution of a hydroxyl group with azide function carbocation, followed by acidolysis of the produced azides (eq.~).~On the other hand, the 1 , % , 2 -3 -Schmidt reaction of adamantanone (4) is known to afford L o r * 8 (fragmentation and n-route cyclization products) and 7Jre-
Understanding Controversial Therapies for Children with Autism, Attention Deficit Disorder, and Other Learning Disabilities: A Guide to Complementary and Alternative Medicine (2008)

Part 1: Introduction. 1. Introduction. 2. Thinking Out of the Box: An Overview of Complementary and Alternative Medicine Approaches. Part 2: Selected Interventions. 3. Alternative Medical Systems. 4. Mind-Body Interventions. 5. Biologically-based Interventions. 6. Manipulative and Body-based Methods. 7. Energy Therapies. Part 3: Resources for Children with Autism, Attentions Deficit Disorders, and other Learning Disabilities. 8. Recommended Reading about Complementary and Alternative Medicine. 9. Agencies, Organizations and Websites. Subject Index. Author Index.
Linear Combinatorial Synthesis with Fourier Transform Library Analysis (2003)

Abstract Feature Article: Combinatorial synthesis procedures that fit a restrictively defined “fully parallel” criterion tend to be extremely efficient methods. We describe how linear library organization allows such synthesis, without loss of synthetic history information, with an example of a peptide library. Fluorescence measurements of several types are used to measure activities. A novel Fourier Transform approach to library data analysis allows robust evaluation of trends. The use of the cladding of optical fibers as linear supports for combinatorial libraries significantly extends the potential applications of the technique, allowing for spatially resolved optical evaluation of library activity using laser pulses propagating through the fiber core. Moreover, by using different fiber cladding materials, the range of chemistries amenable to one‐dimensional combinatorial synthesis is significantly increased. It is noteworthy that the procedure is particularly applicable to the fabrication and evaluation of real‐time sensor arrays. Schematic representation of a fully parallel synthesis on a linear solid support. The result is a sequence of regions on the thread, each bearing a library member. magnified image Schematic representation of a fully parallel synthesis on a linear solid support. The result is a sequence of regions on the thread, each bearing a library member.
A New Class of Medicines through DNA Editing (2019)

Interview with Dr. Matthew H. Porteus on therapeutic editing of the human genome. (12:58)Download Therapeutic editing of the human genome has long been a holy grail of genetic medicine. Different approaches are founded on a bedrock of basic laboratory discovery. This article describes the history, applications, and limitations of genome editing for clinical application.
DIREITOS REAIS - DOMÍNIO E PROPRIEDADE (2010)

Este artigo refere-se à compreensão sobre domínio e propriedade. Desde as palavras do Prof. Dr. Carlos Mario Clerc, proferidas em uma palestra na Universidade do Museu Social - Buenos Aires, Argentina, temos pensado que o tema sobre domínio e propriedade é mais importante que uma simples denominação no campo do conhecimento. Muitos autores pesquisados neste trabalho disseram que a via certa para entender o real sentido sobre domínio e propriedade é a do senso comum de relatividade que tem o direito.
Epidemiological study of<i>Cucumber green mottle mosaic virus</i>in greenhouses enables reduction of disease damage in cucurbit production (2015)

Since 2007, the tobamovirus Cucumber green mottle mosaic virus (CGMMV) has become widespread in Israel, causing severe damage to trellised cucumber and melon in greenhouses and watermelon grown in open fields. To reduce disease damage below the economic threshold, this study focused on four objectives: (a) monitoring the patterns of virus distribution within commercial cucumber greenhouses; (b) studying the potential transmission of CGMMV by agrotechnical activities; (c) virus localization in plant tissues; and (d) searching for techniques that might be adapted for mitigating the disease in trellised cucurbit growth. The results of our surveys demonstrated the role of contaminated seeds and soil as primary inoculum sources, and secondary spread caused by agrotechnical activities. The patterns of secondary disease spread were demonstrated in a series of inoculation experiments involving contaminated knives, shears or hands on wet and dry plants, conducted under research-greenhouse conditions. In parallel experiments using CGMMV-specific antibody and secondary antibody conjugated to Alexa fluor 488, the viral coat protein was visualized in several plant tissues: phloem, xylem, trichomes and grasping tendrils. In addition, commercial-greenhouse experiments were aimed at reducing the number of inoculum sources by identifying and removing infected plants from the plots (early monitoring) prior to agrotechnical activities and/or by adding intermediate medium (IM), such as virus-free compost, to the planting pits at the planting stage. It is suggested that the use of IM combined with early monitoring, awareness of worker mobility (from contaminated structures to young planting areas) and proper sanitation (e.g. disinfection of agrotechnical tools) may reduce the yield losses caused by CGMMV below the economic threshold.
Coaxial Waveguide Based Left-Handed Transmission Line (2007)

In this letter, a new realization of left-handed transmission line (LHTL) is presented; the proposed structure is realized by periodically loading the coaxial waveguide with gaps in the inner conductor and wires between the inner and outer conductors, the gaps and wires act as series capacitors and shunt inductors. The dispersion characteristic of this new LHTL is analyzed by means of high frequency structure simulator (HFSS) eigenmode simulation and microwave network theory, which exhibits LH behavior over a 60% bandwidth. A backward wave behavior is unambiguously demonstrated from HFSS driven modal simulation. The phase front is observed to be in the opposite direction with respect to the energy one for a finite nine-unit cell prototype.
Neuronal Networks on Nanocellulose Scaffolds (2015)

Proliferation, integration, and neurite extension of PC12 cells, a widely used culture model for cholinergic neurons, were studied in nanocellulose scaffolds biosynthesized by Gluconacetobacter xylinus to allow a three-dimensional (3D) extension of neurites better mimicking neuronal networks in tissue. The interaction with control scaffolds was compared with cationized nanocellulose (trimethyl ammonium betahydroxy propyl [TMAHP] cellulose) to investigate the impact of surface charges on the cell interaction mechanisms. Furthermore, coatings with extracellular matrix proteins (collagen, fibronectin, and laminin) were investigated to determine the importance of integrin-mediated cell attachment. Cell proliferation was evaluated by a cellular proliferation assay, while cell integration and neurite propagation were studied by simultaneous label-free Coherent anti-Stokes Raman Scattering and second harmonic generation microscopy, providing 3D images of PC12 cells and arrangement of nanocellulose fibrils, respectively. Cell attachment and proliferation were enhanced by TMAHP modification, but not by protein coating. Protein coating instead promoted active interaction between the cells and the scaffold, hence lateral cell migration and integration. Irrespective of surface modification, deepest cell integration measured was one to two cell layers, whereas neurites have a capacity to integrate deeper than the cell bodies in the scaffold due to their fine dimensions and amoeba-like migration pattern. Neurites with lengths of >50 μm were observed, successfully connecting individual cells and cell clusters. In conclusion, TMAHP-modified nanocellulose scaffolds promote initial cellular scaffold adhesion, which combined with additional cell-scaffold treatments enables further formation of 3D neuronal networks.
Enamel matrix derivative enhances tissue formation around scaffolds used for tissue engineering of ligaments (2009)

The following in vitro translational study investigated whether enamel matrix derivative (EMD), an approved biomimetic treatment for periodontal disease (Emdogain) and hard-to-heal wounds (Xelma), enhanced synovial cell colonization and protein synthesis around a scaffold used clinically for in situ tissue engineering of the torn anterior cruciate ligament (ACL). Synovial cells were enzymatically extracted from bovine synovium and dynamically seeded onto polyethylene terephthalate (PET) scaffolds. The cells were cultured in low-serum medium (0.5% FBS) for 4 weeks with either a single administration of EMD at the start of the 4 week period or multiple administrations of EMD at regular intervals throughout the 4 weeks. Samples were harvested and evaluated using the Hoechst DNA assay, BCA protein assay, cresolphthalein complexone calcium assay, SDS-PAGE, ELISA and electron microscopy. A significant increase in cell number (DNA) (p < 0.01), protein content (p < 0.01) and TGFbeta1 synthesis (p < 0.01) was observed with multiple administrations of EMD. Additionally, SDS-PAGE showed an increase in high molecular weight proteins, characteristic of the fibril-forming collagens. Electron microscopy supported these findings, showing that scaffolds treated with multiple administrations of EMD were heavily coated with cells and extracellular matrix (ECM) that enveloped the fibres. Multiple administrations of EMD to synovial cell-seeded scaffolds enhanced the formation of tissue in vitro. Additionally, it was shown that EMD enhanced TGFbeta1 synthesis of synovial cells, suggesting a potential mode of action for EMD's capacity to stimulate tissue regeneration.
Using Eye Movements to Evaluate the Cognitive Processes Involved in Text Comprehension (2014)

The present article describes how to use eye tracking methodologies to study the cognitive processes involved in text comprehension. Measuring eye movements during reading is one of the most precise methods for measuring moment-by-moment (online) processing demands during text comprehension. Cognitive processing demands are reflected by several aspects of eye movement behavior, such as fixation duration, number of fixations, and number of regressions (returning to prior parts of a text). Important properties of eye tracking equipment that researchers need to consider are described, including how frequently the eye position is measured (sampling rate), accuracy of determining eye position, how much head movement is allowed, and ease of use. Also described are properties of stimuli that influence eye movements that need to be controlled in studies of text comprehension, such as the position, frequency, and length of target words. Procedural recommendations related to preparing the participant, setting up and calibrating the equipment, and running a study are given. Representative results are presented to illustrate how data can be evaluated. Although the methodology is described in terms of reading comprehension, much of the information presented can be applied to any study in which participants read verbal stimuli.