gebhart/patrepeval huggingface dataset:
Boronic Acids in the Three-Component Synthesis of Carbon-Substituted Cyclopentadienyl Tricarbonyl Rhenium Complexes (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTBoronic Acids in the Three-Component Synthesis of Carbon-Substituted Cyclopentadienyl Tricarbonyl Rhenium ComplexesFilippo Minutolo and John A. KatzenellenbogenView Author Information Department of Chemistry, University of Illinois 600 South Mathews Avenue, Urbana, Illinois 61801 Cite this: J. Am. Chem. Soc. 1998, 120, 50, 13264–13265Publication Date (Web):December 4, 1998Publication History Received22 June 1998Published online4 December 1998Published inissue 1 December 1998https://pubs.acs.org/doi/10.1021/ja982146shttps://doi.org/10.1021/ja982146srapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views354Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info ()»Supporting Information Supporting Information SUBJECTS:Organometallic reactions,Precursors,Reactivity,Rhenium,Substitution reactions Get e-Alerts
Production of Cellulolytic Enzymes by <i>Rhizopus Oryzae</i> in Culture and <i>Rhizopus</i> -Infected Tissues of Potato Tubers (1993)

Click to increase image sizeClick to decrease image sizeKey Words: endo-β-1,4-glucanase (Cx cellulase)exo-β-1,4-glucanase (C1 cellulase)in vitroin vivopHRhizopus oryzaeSolanum tuberosumtemperature
Induction of Porphyrin Synthesis in Etiolated Bean Leaves by Chelators of Iron (1974)

Primary leaves of 7- to 9-day-old etiolated seedlings of Phaseolus vulgaris L. var. Red Kidney infiltrated in darkness with aqueous solutions of alpha, alpha'-dipyridyl, o-phenanthroline, pyridine-2-aldoxime, pyridine-2-aldehyde, 8-hydroxyquinoline, or picolinic acid synthesize large amounts of magnesium protoporphyrin monomethyl ester and lesser amounts of magnesium protoporphyrin, protoporphyrin, and protochlorophyllide. Pigment formation proceeds in a linear manner for up to 21 hours after vacuum infiltration with 10 mm alpha, alpha'-dipyridyl. Etiolated tissues of Zea mays L., Cucumis sativus L., and Pisum sativum L. respond in the same way to dipyridyl treatment. Compounds active in eliciting this response are aromatic heterocyclic nitrogenous bases which also act as bidentate chelators and form extremely stable complexes with iron; other metal ion chelators, such as ethylenediaminetetraacetic acid, salicylaldoxime, and sodium diethyldithiocarbamate, do not elicit any pigment synthesis. The ferrous, ferric, cobaltous, and zinc chelates of alpha, alpha'-dipyridyl are similarly ineffective. If levulinic acid is supplied to etiolated bean leaves together with alpha, alpha'-dipyridyl, porphyrin production is inhibited and delta-aminolevulinic acid accumulates in the tissue. Synthesis of porphyrins proceeds in the presence of 450 micrograms per milliliter chloramphenicol or 50 micrograms per milliliter cycloheximide with only partial diminution. We propose that heme or an iron-protein complex blocks the action of the enzyme(s) governing the synthesis of delta-aminolevulinic acid in etiolated leaves in the dark and that iron chelators antagonize this inhibition, leading to the biosynthesis of delta-aminolevulinic acid and porphyrins.
A Tribute to Dr. John H. Greve (1997)

Picture this: it's a wonderful day outside, the birds are singing, the sun is out, and you are stuck in class. As you thumb through the literary genius of the Daily looking for the crossword puzzle or chat with the person next to you about how you just got hammered on the last pathology test, a deep rich baritone voice booms out "Welllllll ... Gooooood Morning!!!" and parasitology class begins. For those veterinarians who have graduated in the last several years, you will recognize the style of Dr. John H. Greve.
Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8 (2010)

53BP1 is a well-known mediator of the cellular response to DNA damage. Two alternative mechanisms have been proposed to explain 53BP1's interaction with DNA double-strand breaks (DSBs), one by binding to methylated histones and the other via an RNF8 E3 ligase-dependent ubiquitylation pathway. The formation of RNF8 and 53BP1 irradiation-induced foci are both dependent on histone H2AX. To evaluate the contribution of the RNF8-dependent pathway to 53BP1 function, we generated RNF8 knockout mice. We report that RNF8 deficiency results in defective class switch recombination (CSR) and accumulation of unresolved immunoglobulin heavy chain-associated DSBs. The CSR DSB repair defect is milder than that observed in the absence of 53BP1 but similar to that found in H2AX(-/-) mice. Moreover, similar to H2AX but different from 53BP1 deficiency, RNF8(-/-) males are sterile, and this is associated with defective ubiquitylation of the XY chromatin. Combined loss of H2AX and RNF8 does not cause further impairment in CSR, demonstrating that the two genes function epistatically. Importantly, although 53BP1 foci formation is RNF8 dependent, its binding to chromatin is preserved in the absence of RNF8. This suggests a two-step mechanism for 53BP1 association with chromatin in which constitutive loading is dependent on interactions with methylated histones, whereas DNA damage-inducible RNF8-dependent ubiquitylation allows its accumulation at damaged chromatin.
Air-Stable Molecular Semiconducting Iodosalts for Solar Cell Applications: Cs<sub>2</sub>SnI<sub>6</sub> as a Hole Conductor (2014)

We introduce a new class of molecular iodosalt compounds for application in next-generation solar cells. Unlike tin-based perovskite compounds CsSnI3 and CH3NH3SnI3, which have Sn in the 2+ oxidation state and must be handled in an inert atmosphere when fabricating solar cells, the Sn in the molecular iodosalt compounds is in the 4+ oxidation state, making them stable in air and moisture. As an example, we demonstrate that, using Cs2SnI6 as a hole transporter, we can successfully fabricate in air a solid-state dye-sensitized solar cell (DSSC) with a mesoporous TiO2 film. Doping Cs2SnI6 with additives helps to reduce the internal device resistance, improving cell efficiency. In this way, a Z907 DSSC delivers 4.7% of energy conversion efficiency. By using a more efficient mixture of porphyrin dyes, an efficiency near 8% with photon confinement has been achieved. This represents a significant step toward the realization of low-cost, stable, lead-free, and environmentally benign next-generation solid-state solar cells.
Efficacy and tolerability of diclofenac potassium sachets in acute postoperative dental pain: a placebo-controlled, randomised, comparative study vs. diclofenac potassium tablets (2006)

This double-blind, randomised, parallel-group trial compared the analgesic efficacy of single 50 mg doses of diclofenac potassium sachets and tablets with placebo in 184 patients with moderate/severe pain after third molar extraction. The primary efficacy variable was the average pain reduction from baseline during the first 2-h postdose, using a visual analogue scale (VAS). During the first 2-h postdose, sachets and tablets significantly reduced pain (p < 0.05) vs. placebo with an incremental benefit seen for sachets over tablets (p < 0.05). Onset of analgesic effect (VAS) was at 30 min for sachets and 45 min for tablets. Pain reduction vs. placebo (VAS) was maintained for 8 h for sachets and tablets (p < 0.05). VAS-findings were confirmed by pain relief and intensity verbal scale assessments. Fewer patients re-medicated vs. placebo. No safety issues were identified. This study demonstrates that both diclofenac potassium sachets and tablets offer patients suffering from acute pain conditions an effective treatment with incremental analgesic benefits seen for sachets.
A method for flight-test determination of propulsive efficiency and drag (1985)

A flight-test method is described from which propulsive efficiency as well as parasite and induced drag coefficients can be directly determined using relatively simple instrumentation and analysis techniques. The method uses information contained in the transient response in airspeed for a small power change in level flight in addition to the usual measurement of power required for level flight. Measurements of pitch angle and longitudinal and normal acceleration are eliminated. The theoretical basis for the method, the analytical techniques used, and the results of application of the method to flight-test data are presented. Flight-test data showed performance parameters measured with a standard deviation of about 0.8% for propulsive efficiency, 0.3% for parasite drag coefficient, and 8% for the airplane efficiency factor, e.
A Study on the Thermal Characteristics of Midsummer in Daegu Metropolitan Area (2013)

This study aims to examine the actual status of the urban heat island in Daegu by analyzing the data of 17 automatic weather stations installed in the Daegu area. And the results can be summarized as follows: First, regarding the temperature distribution in Daegu by summer time zones, for the 31 days(August 1st till 31st), 18 days showed daily maximum temperature over <TEX>$30^{\circ}C$</TEX>, and 11 days indicated daily minimum temperature over <TEX>$25^{\circ}C$</TEX>. The day that showed the highest daily maximum temperature was August 5th, which indicated <TEX>$36^{\circ}C$</TEX>. Second, about the spatial distribution of time ratio exceeding <TEX>$30^{\circ}C$</TEX> and <TEX>$25^{\circ}C$</TEX>, the area with the highest time ratio exceeding <TEX>$30^{\circ}C$</TEX> is mostly the downtown(central area), eastern area, and northern area. Meanwhile, regarding the time ratio exceeding <TEX>$25^{\circ}C$</TEX>, the downtown area centering around the central area were high as over 70%, and the outskirts were low as under 65%. Third, considering the temporal distribution of daily maximum temperature and daily minimum temperature, daily maximum temperature was shown around 14:00 to 15:00 while the daily minimum temperature was indicated around 17:00 to 18:00. Daily maximum and minimum temperature were appeared at northeast and downtown, respectively. Fourth, regarding the spatial distribution of tropical days and tropical night days, tropical days showed 77% and tropical night days indicated 42% before and after the 24th and also the 13th each. Tropical days were occurred up to 24 days at northeastern area. And the southwestern area of Daegu showed under 22 days. The downtown showed the 14 days of the tropical night. However, the outskirts indicated relatively few days as under 10 days. Fifth, about the spatial distribution of the average daily temperature range (the difference between the highest temperature and lowest temperature), the central area, the central part of the city, showed the smallest as <TEX>$7.2^{\circ}C$</TEX>, and as it was closer to the northern area, it became larger, so in the eastern and northern area, it was over <TEX>$8.8^{\circ}C$</TEX> or so.
Secondary Use of the EHR via Pseudonymisation (2004)

The Electronic Health Record (EHR) has many secondary uses, such as health economy and health care research, or disease specific clinical or epidemiological research. For these uses in general the patient identity is not needed, therefore the data must be anonymised or pseudonymised. Whereas for one-time use of the data this procedure is straightforward, long-term data accumulation or the necessity of re-identification require a more sophisticated approach. This paper describes possible model architectures, developed for medical research networks, but useful in other contexts as well.
Single Grating Integrated Optical Autocorrelation Device (1984)

A real time integrated optical autocorrelation device is proposed which offers the potential for improved performance and ease of fabrication over existing alternatives. An analysis of the signal processing capabilities of this guided wave device is presented and a comparison is made to other integrated optical approaches.
Microencapsulation of Oils: A Comprehensive Review of Benefits, Techniques, and Applications (2015)

Microencapsulation is a process of building a functional barrier between the core and wall material to avoid chemical and physical reactions and to maintain the biological, functional, and physicochemical properties of core materials. Microencapsulation of marine, vegetable, and essential oils has been conducted and commercialized by employing different methods including emulsification, spray-drying, coaxial electrospray system, freeze-drying, coacervation, in situ polymerization, melt-extrusion, supercritical fluid technology, and fluidized-bed-coating. Spray-drying and coacervation are the most commonly used techniques for the microencapsulation of oils. The choice of an appropriate microencapsulation technique and wall material depends upon the end use of the product and the processing conditions involved. Microencapsulation has the ability to enhance the oxidative stability, thermostability, shelf-life, and biological activity of oils. In addition, it can also be helpful in controlling the volatility and release properties of essential oils. Microencapsulated marine, vegetable, and essential oils have found broad applications in various fields. This review describes the recognized benefits and functional properties of various oils, microencapsulation techniques, and application of encapsulated oils in various food, pharmaceutical, and even textile products. Moreover, this review may provide information to researchers working in the field of food, pharmacy, agronomy, engineering, and nutrition who are interested in microencapsulation of oils.
Laparoscopic partial nephrectomy (2003)

We retrospectively reviewed the clinical results of 24 patients who underwent laparoscopic partial nephrectomy by a diagnosis of renal cell carcinoma (RCC) between 1999 and 2004, including 16 elective cases and 8 imperative cases. Twenty-two were successfully treated laparoscopically; two cases in the imperative group required conversion to open surgery because of uncontrollable bleeding. A vascular clamp was used in 12 cases for an average of 26 minutes. The creatinine clearance changed from 98 to 93 ml/min in the elective cases and from 49 to 44 ml/min in the imperative cases. Pathological evaluation revealed RCC in 10 elective cases and 6 imperative cases. Local recurrence (renal hilum lymph node and ipsilateral kidney) was found in 2 patients in the imperative group. Although laparoscopic partial nephrectomy is useful, long-term follow-up is necessary for evaluating the tumor control.
The Probabilistic Program Dependence Graph and Its Application to Fault Diagnosis (2010)

This paper presents an innovative model of a program's internal behavior over a set of test inputs, called the probabilistic program dependence graph (PPDG), which facilitates probabilistic analysis and reasoning about uncertain program behavior, particularly that associated with faults. The PPDG construction augments the structural dependences represented by a program dependence graph with estimates of statistical dependences between node states, which are computed from the test set. The PPDG is based on the established framework of probabilistic graphical models, which are used widely in a variety of applications. This paper presents algorithms for constructing PPDGs and applying them to fault diagnosis. The paper also presents preliminary evidence indicating that a PPDG-based fault localization technique compares favorably with existing techniques. The paper also presents evidence indicating that PPDGs can be useful for fault comprehension.
Proteomics Analysis of Rat Brain Protein Modulations by Grape Seed Extract (2004)

Dietary supplements such as grape seed extract (GSE) enriched in proanthocyanidins (PA) (oligomeric polyphenols) have been suggested to have multiple health benefits, due to antioxidant and other beneficial activities of the PA. However, a systematic analysis of the molecular basis of these benefits has not been demonstrated. Because the brain is vulnerable to age-related oxidative damage and other insults including inflammation, it was hypothesized that rats ingesting GSE would experience changes in expression or modifications of specific brain proteins that might protect against pathologic events. Normal adult female rats were fed diets supplemented with 5% GSE for 6 weeks. Proteomics analysis (2D electrophoresis and mass spectrometry) of brain homogenates from these animals identified 13 proteins that were altered in amount and/or charge. Because many of these changes were quantitatively in the opposite direction from previous findings for the same proteins in either Alzheimer disease or mouse models of neurodegeneration, the data suggest that these identified proteins may mediate the neuroprotective actions of GSE. This is the first identification and quantitation of specific proteins in mammalian tissues modulated by a dietary supplement, as well as the first to demonstrate links of such proteins with any disease.
Upregulation of CD22 by Chidamide Promotes CAR T Cells Functionality (2021)

Abstract Treatment failure or relapse due to tumor escape caused by reduction in target antigen expression has become a challenge in the field of CART therapy. Target antigen density is closely related to the effectiveness of CART therapy, and reduced or lost target antigen expression limits the efficacy of CART therapy and hinders the durability of CAR T cells. Epigenetic drugs can regulate histones for molecular modifications to regulate the transcriptional, translational and post-translational modification processes of target agents., and we demonstrated for the first time the role in regulating CD22 expression and its effect on the efficacy of CD22 CART. In this paper, we found that Chidamide promoted the expression of CD22 on the surface of B-cell tumor cells in vitro and in vivo, and enhanced the function of CD22 CART. As for mechanisms, we demonstrated that Chidamide did not affect CD22 mRNA transcription, but significantly increased the expression of total CD22 protein, indicating that Chidamide may upregulate cell surface CD22 expression by affecting the distribution of CD22 protein. In summary, our results suggest that Chidamide may enhance the efficacy of CD22 CART by inhibiting histone deacetylases to regulate post-transcriptional modifications that affect protein distribution to increase the expression of CD22 on the cell surface.
Anti-IgG binding test to assay circulating IgG-containing immune complexes from polyethylene glycol precipitates. (1984)

We describe a simple approach for assaying immune complexes from serum by using anti-IgG as the indicator after a three-step extraction procedure with polyethylene glycol. Analysis of the data indicates that assays of such extracts for immune complexes by absorbance nephelometry, kinetic light scatter, and immunoradiometric techniques correlate well. For 116 samples, results by absorbance nephelometry correlated (r = 0.86) with those by the C1q-binding test. The present assay and the Raji cell test were more sensitive than the C1q-binding test (p less than 0.001) for detecting increased concentrations of immune complexes in 29 samples from patients with immune-complex-type diseases. The basic approach we describe may lend itself to broad applications for use with various immunoassay techniques.
Improvement of psoriasis and cutaneous side-effects during tyrosine kinase inhibitor therapy for renal metastatic adenocarcinoma. A role for epidermal growth factor receptor (EGFR) inhibitors in psoriasis? (2006)

Journal Article Improvement of psoriasis and cutaneous side‐effects during tyrosine kinase inhibitor therapy for renal metastatic adenocarcinoma. A role for epidermal growth factor receptor (EGFR) inhibitors in psoriasis? Get access E. Wierzbicka, E. Wierzbicka Department of Dermatology and Medical Oncology Unit, University of Poitiers Medical School, Rue de la Milétrie, BP577, 86021 Poitiers Cedex, France E‐mail: e.wierzbicka@chu‐poitiers.fr Search for other works by this author on: Oxford Academic Google Scholar J.M. Tourani, J.M. Tourani Department of Dermatology and Medical Oncology Unit, University of Poitiers Medical School, Rue de la Milétrie, BP577, 86021 Poitiers Cedex, France E‐mail: e.wierzbicka@chu‐poitiers.fr Search for other works by this author on: Oxford Academic Google Scholar G. Guillet G. Guillet Department of Dermatology and Medical Oncology Unit, University of Poitiers Medical School, Rue de la Milétrie, BP577, 86021 Poitiers Cedex, France E‐mail: e.wierzbicka@chu‐poitiers.fr Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 155, Issue 1, 1 July 2006, Pages 213–214, https://doi.org/10.1111/j.1365-2133.2006.07299.x Published: 01 July 2006
A Hybrid Localization Framework for Mobile Devices (2014)

We are presenting a novel hybrid mobile localization system for smart mobile devices which combines the prevalence of classical wireless methods with accuracy of computer vision techniques. In the proposed framework, initial localization is roughly measured through classical wireless methods. Later computer vision techniques are deployed to refine the measurement. Specifically an image acquired by the device's camera is matched against 3D model fragments. The key innovation of the framework is to keep a pool of 3D model fragments, indexed by their rough location info, rather than a monolithic 3D model of the environment. Thanks to the location indexed fragments, computer vision computations become reasonable enough to carry on a modern smart-phone. Also, network traffic and mobile storage requirements are minimized by on-demand caching. The 3D models that are needed by the system can come from modern cheap 3D depth sensors or recently matured depth from image sequences techniques. We expect such an approach would be especially useful for Augmented Reality applications that require good localization accuracy.
Applications of superconductivity to packaging (1989)

The properties of superconductors are reviewed, and the potential applications of high-temperature superconductors to interconnect technology are examined. Comparison with interconnects composed of normal metals is made. The effect of source and load impedances on both types of interconnect is discussed. Examples are presented in which the use of superconductors can significantly improve digital systems; however, they involve much more than the simple substitution of superconductors for copper. Modeling results show that if all copper interconnects in the ETA-10 liquid nitrogen supercomputer were replaced by superconductors, the computer would not run any faster. It is argued that imaginative use of superconductors will eventually have a major impact on digital systems, nevertheless. Two possibilities are the use of a superconducting ground plane and a high-bandwidth superconducting bus.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>