gebhart/patrepeval huggingface dataset:
Design and development of side underride protection devices (SUPD) for heavy vehicles (2014)

There exists a large mismatch between the bumper of a passenger vehicle and the ground clearance of heavy vehicles. During collisions between the car and the side of the heavy vehicle, a large amount of intrusion is observed in the passenger compartment due to underride. The results of these collisions often leads to injuries or fatalities. This research aims to develop side underride protection devices (SUPD) to eliminate the incompatibility between the small vehicle???s bumper and bottom of the trailer or box of the straight truck. To successfully design these guards, a regulation for testing the effectiveness of the SUPDs during a side crash was created. Guards were then developed utilizing a topology and multi-objective optimization design approach by applying the proposed regulation. These proved feasible when tested dynamically with the Toyota Yaris and Ford Taurus at preventing underride. Additional guards were then created and tested utilizing an aerodynamic shape to reduce drag and improve fuel consumption.
Building and search system for a large-scale DNA database (1994)

The authors newly developed a hierarchical relational schema for effectively building, integrating, and searching the DNA database on the relational database management system, SYBASE, at DDBJ. The scheme is named the 'DDBJ-schema'. The schema allowed the authors to implement window interfaces to easily build the DNA database. The DNA database built in the GenBank-schema using AWB is converted into the relational format of the DDBJ-schema using a restructuring tool at DDBJ. A virtual-structured SQL-programing method is proposed to implement the restructuring tool. The method is developed through the 'view' function and the control flow language (CFL) of SYBASE. Moreover, the authors also proposed two methodologies by which one can execute these software tools on UNIX based workstations connected by a computer network.
An Investigation of the Cross-Spring Pivot (1944)

Abstract It is the purpose of this paper to describe the characteristics of the cross-spring pivot, or elastic hinge, for large deflection angles. Design formulas are established for certain standard forms of the two-spring pivot on the basis of experimental results. Formulas are developed for the spring constant, bending stress, and motion of the pivot point; their application is illustrated by an example. A comparison of the various pivots, when used in lever systems, is made, and suggestions for the design of two-spring pivots are included.
Increase in CIP2A expression is associated with doxorubicin resistance (2011)

The cancerous inhibitor of protein phosphatase 2A (CIP2A) increases the migration and metastasis of various cancer cells. Overexpression of CIP2A has been shown to increase the proliferation of MDA-MB-231 cells. We thus assessed whether CIP2A expression is associated with sensitivity to doxorubicin. MDA-MB-231 cells showed an increase in CIP2A expression after treatment with doxorubicin, while MCF-7 cells showed a decrease in CIP2A expression. The overexpression of CIP2A in MCF-7 cells overcame the inhibition of cell proliferation in response to doxorubicin treatment. CIP2A expression was not affected by wild-type or mutant p53. However, mutant p53 blocked doxorubicin-mediated CIP2A down-regulation in HCT116 cells. As a regulation mechanism of doxorubicin-mediated CIP2A expression, we showed that phosphorylated Akt was involved in the suppression of CIP2A expression.
I COVID-19 karantæne på Egmont Kollegiet: Indblik i et udfordret kærlighedsliv og en forhandlet moralitet (2020)

I foråret 2020 blev livet på Egmont Kollegiet vendt på hovedet. Stedet er kendt for dets unikke fællesskab, vilde fester, foranderlige flirts og forelskelser på tværs af kollegiegangene. Men da COVID-19 spreder sigi Danmark, opstår der små gangfællesskaber præget af frygt og social kontrol. For at beskytte sig mod smitte, griber beboerne ind i hinandens privatliv med retningslinjer, der rækker ud over sundhedsvæsenets anbefalinger. Artiklen giver et indblik i unges håndtering af en alvorlig smittefare, og i hvordan en virus, i tæt forbindelse med sundhedsmæssige og politiske anbefalinger, kan føre til forhandling af samvær, kærlighedsliv og moralitet.
Formation of ZnMn<sub>2</sub>O<sub>4</sub> Ball‐in‐Ball Hollow Microspheres as a High‐Performance Anode for Lithium‐Ion Batteries (2012)

Novel ZnMn(2)O(4) ball-in-ball hollow microspheres are fabricated by a facile two-step method involving the solution synthesis of ZnMn-glycolate hollow microspheres and subsequent thermal annealing in air. When evaluated as an anode material for lithium-ion batteries, these ZnMn(2)O(4) ball-in-ball hollow microspheres show significantly enhanced electrochemical performance with high capacity, excellent cycling stability and good rate capability.
NetCluster: A Clustering-Based Framework for Internet Tomography (2009)

In this paper, Internet data collected via passive measurement are analyzed to obtain localization information on nodes by clustering (i.e., grouping together) nodes that exhibit similar network path properties. Since traditional clustering algorithms fail to correctly identify clusters of homogeneous nodes, we propose a novel framework, named "NetCluster", suited to analyze Internet measurement datasets. We show that the proposed framework correctly analyzes synthetically generated traces. Finally, we apply it to real traces collected at the access link of our campus LAN and discuss the network characteristics as seen at the vantage point.
Study on CD variation in the vicinity of the exposure field edge in EUV lithography (2012)

Intra-field CD uniformity control is one of hurdles in EUV lithography. Reflection imaging system intrinsic to EUV causes CD non-uniformity especially in exposure field edge. To analyze dominant contributors to make this intra-field CD non-uniformity in EUV lithography, influence of flare from adjacent fields and in-band and out of band refection from reticle masking blind(REMA) and mask black border were investigated through intensive sampling of CD measurement. Also mask border condition and REMA open settings are split into various settings to find out the impacts from each contributor. Two ASML EUV scanners, alpha demo tool(ADT) and pre-production tool(PPT) are used for the experiment. Fortunately, DUV out of band(OoB), reflection of REMA and the flare from adjacent fields are found to be not significant in NXE3100. The results presented here lead us to the conclusion that the EUV refection from mask black border is the main contributor and CD non-uniformity of the field edge can be overcome through optimized REMA setting.
A Randomized Comparison of Antiplatelet and Anticoagulant Therapy after the Placement of Coronary-Artery Stents (1996)

As compared with conventional anticoagulant therapy, combined antiplatelet therapy after the placement of coronary-artery stents reduces the incidence of both cardiac events and hemorrhagic and vascular complications.
Hair motion reconstruction using motion capture system (2007)

Processes such as modeling, rendering and simulating hair are essential for creating virtual humans in various CG applications. CG hair motion simulations are commonly constructed using a physics-based model and have been extensively researched. While physics-based approaches have achieved effective and sophisticated hair motion, data-driven approaches for hair motion have been scarcely researched. This paper therefore outlines our hair animation approach which uses Motion Capture System to capture 3D hair motion. Our approach enables users to easily simulate complex hair motions such as the collision between hair strands and the human body and the movement of hair strands as they are blown in a variety of directions by wind.
A New Anti-influenza Virus Antibiotic, 10-Norparvulenone from Microsphaeropsis sp. FO-5050. (2000)

Influenza virus infection is widespread and sometimes critical for patients with respiratory diseases, immunosuppressive syndromes such as AIDS, aged persons with cardiopulmonary diseases and so on1}. Although several anti-influenza virus agents such as amantadine, rimantadine and zanamivir have been used, they are not always effective. The side-effects and rapid development of viral resistance cause limited medical application2'^. For these reasons, new effective anti-influenza viral drugs are required. Recently, we screened anti-influenza virus compounds from culture broths of actinomycetes and fungi. The screening was
Facilitation of recovery from ischemic brain damage in rabbits by polymeric prostaglandin PGBx, a mitochondrial protective agent. (1980)

Administration of polymeric prostaglandin PGBx to rabbits after a 20-minute period of almost total obstruction of blood flow to the brain resulted in marked improvement of recovery from brain damage as measured by recovery of brain function. This beneficial effect of PGBx on recovery from acute ischemic tissue damage, analogous to that observed in cardiac tissue of monkeys, may be due to the positive effect of PGBx on phosphorylation in damaged mitochondria as observed previously in vitro. A convenient surgical technique for producing reversible cerebral ischemia in rabbits was developed for and used in this pharmacological study.
Antioxidant galloylated flavonol glycosides from <b> <i>Calliandra haematocephala</i> </b> (2006)

Three new acylated quercetin rhamnosides have been isolated from the leaves and stem of Calliandra haematocephala Hassk. (Fabaceae) and their structures were established as quercitrin 2''-O-caffeate (1), quercitrin 3''-O-gallate (2) and quercitrin 2'',3''-di-O-gallate (3). Also, 17 known compounds were identified as gallic acid (4), methyl gallate (5), caffeic acid (6), myricitrin (7), quercitrin (8), myricetin 3-O-beta-D-4C1-glucopyranoside (9), afzelin (10), isoquercitrin (11), myricetin 3-O-(6''-O-galloyl)-beta-D-glucopyranoside (12), myricitrin 2''-O-gallate (13), quercitrin 2''-O-gallate (14), afzelin 2''-O-gallate (15), myricitrin 3''-O-gallate (16), afzelin 3''-O-gallate (17), 1,2,3,4,6-penta-O-galloyl-beta-D-4C1-glucopyranose (18), myricitrin 2'',3''-di-O-gallate (19), quercetin 3-O-methyl ether (20), for the first time from the genus Calliandra except for 6. Compounds 7, 8, 13, 14, 16 and 19 exhibited moderate to strong radical scavenging properties on lipid peroxidation, hydroxyl radical, superoxide anion generation and DPPH radical in comparison with that of quercetin as a positive control in vitro. Compounds 7 and 8 exhibited lethal effect towards brine shrimp Artemia salina.
A new architecture for frequency-selective digital predistortion linearization for RF power amplifiers (2012)

This paper presents a new architecture for frequency-selective digital predistortion (DPD) for two-band PA linearization. The algorithm used accounts for differential memory effects up to 5th order for bands which can be arbitrarily spaced. The preliminary demonstration study is performed using 2-band multi-tone signals with various tone spacing and band separation. The test signal and the linearization algorithm were implemented on a field programmable gate array (FPGA). The linearization algorithm was applied to an RF amplifier at 965 MHz. In the preliminary test for the multitone signals, the 3rd and 5th order distortion were reduced below the noise floor yielding an IMD/ACPR of 55 dB.
Fan-out elements recorded as volume holograms: optimized recording conditions (1992)

The recording of efficient fan-out elements as volume holograms is investigated by using the coupled-wave theory. In contrast to the results published in the standard literature, we find that the efficiency and the uniformity of regular fan-out elements depend strongly on the relative phases of the object waves, at least, if the thickness of the hologram is less than ~50 wavelengths. High efficiency and uniformity can be achieved by optimized recording conditions. At the same time, the required dynamic range of the holographic material becomes minimum.
Enhanced Mechanical Properties of Graphene/Copper Nanocomposites Using a Molecular‐Level Mixing Process (2013)

RGO flakes are homogeneously dispersed in a Cu matrix through a molecular-level mixing process. This novel fabrication process prevents the agglomeration of the RGO and enhances adhesion between the RGO and the Cu. The yield strength of the 2.5 vol% RGO/Cu nanocomposite is 1.8 times higher than that of pure Cu. The strengthening mechanism of the RGO is investigated by a double cantilever beam test using the graphene/Cu model structure.
TDP-43 Depletion Induces Neuronal Cell Damage through Dysregulation of Rho Family GTPases (2009)

The 43-kDa TAR DNA-binding protein (TDP-43) is known to be a major component of the ubiquitinated inclusions characteristic of amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusions. Although TDP-43 is a nuclear protein, it disappears from the nucleus of affected neurons and glial cells, implicating TDP-43 loss of function in the pathogenesis of neurodegeneration. Here we show that the knockdown of TDP-43 in differentiated Neuro-2a cells inhibited neurite outgrowth and induced cell death. In knockdown cells, the Rho family members RhoA, Rac1, and Cdc42 GTPases were inactivated, and membrane localization of these molecules was reduced. In addition, TDP-43 depletion significantly suppressed protein geranylgeranylation, a key regulating factor of Rho family activity and intracellular localization. In contrast, overexpression of TDP-43 mitigated the cellular damage caused by pharmacological inhibition of geranylgeranylation. Furthermore administration of geranylgeranyl pyrophosphate partially restored cell viability and neurite outgrowth in TDP-43 knockdown cells. In summary, our data suggest that TDP-43 plays a key role in the maintenance of neuronal cell morphology and survival possibly through protein geranylgeranylation of Rho family GTPases.
Channel Estimation Using Cyclic Delay Pilot for SC-MIMO Multiplexing (2008)

In the next generation mobile communication systems, multiple-input multiple-output (MIMO) multiplexing is an indispensable technique to achieve very high-speed data transmission with a limited bandwidth. In MIMO multiplexing, it is necessary to estimate the channels between transmit and receive antennas for signal detection. In this paper, we propose a minimum mean square error (MMSE) channel estimation using cyclic delay pilot for single-carrier (SC)-MIMO multiplexing. In the proposed channel estimation, the same pilot block is altered through the addition of different cyclic delays and transmitted from different antennas at the same time for simultaneous estimation of all channels between transmit and receive antennas. We evaluate by computer simulation the bit error rate (BER) performance of MIMO multiplexing using the proposed channel estimation and compare it to those using time-multiplexed pilot based channel estimation (TMP-CE) and code-multiplexed pilot based channel estimation (CMP-CE).
3-Substituted 9-Methyl-3,9-Diazabicyclo[3.3.1]nonanes (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT3-Substituted 9-Methyl-3,9-Diazabicyclo[3.3.1]nonanesEdgar A. Steck, Lynn T. Fletcher, and R. Pauline BrundageCite this: J. Org. Chem. 1963, 28, 9, 2233–2238Publication Date (Print):September 1, 1963Publication History Published online1 May 2002Published inissue 1 September 1963https://pubs.acs.org/doi/10.1021/jo01044a019https://doi.org/10.1021/jo01044a019research-articleACS PublicationsRequest reuse permissionsArticle Views111Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Butyrophilin 3A (BTN3A, CD277)‐specific antibody 20.1 differentially activates Vγ9Vδ2 TCR clonotypes and interferes with phosphoantigen activation (2017)

Phosphoantigens (PAgs)-like HMBPP ((E)-4-hydroxy-3-methyl-but-2-enyl diphosphate) and butyrophilin 3 (BTN3A, CD277)-specific monoclonal antibody 20.1 induce TCR-mediated activation of Vγ9Vδ2 T cells. Here, we compared murine reporter cells transduced with Vγ9Vδ2 TCRs G115, D1C55, and MOP for the activation in culture with human RAJI cells and PAgs or mAb 20.1 and its single-chain (sc) derivative. All transductants responded readily to PAg but only TCR MOP γ-chain-expressing cells responded to mAb/sc 20.1. Furthermore, both antagonist and agonist mAb and sc of the agonist mAb inhibited the PAg response of TCR-transduced murine reporter cells. These findings suggest that, in contrast to stimulation by physiological stimulators (PAg), the responsiveness to mAb 20.1 depends strongly on CDR3 sequences of the TCR, and that mAb 20.1 can interfere with the PAg-response. Mouse or human origin of reporter cells might affect the mAb 20.1 response since all three TCR-mediated mAb 20.1-induced activation of TCR-transduced Jurkat cells. The pronounced differences between PAg and mAb 20.1-induced activation observed here help to understand the often contradictory published data. This study provides novel perspectives on the physiological mechanism of Vγ9Vδ2 T-cell activation, and highlights the complex mode of action of BTN3A-specific antibodies as agents in cancer immunotherapy.
A novel approach for antibody nanocarriers development through hydrophobic ion-pairing complexation (2014)

IgG-Fab fragment, a model antibody protein was hydrophobically modified by a novel approach of ion-pairing complexation. Three different sulphated ion-pairing agents were utilised including sodium dodecyl sulphate, taurocholic acid and dextran sulphate (DS). The formations of hydrophobic ion-pairing (HIP) complexes were dependant on pH and molar ratio of ion-pairing agent to Fab. Aqueous solubilities of HIP complexes were very low compared to Fab alone. In particular, when dextran sulphate was added as ion-pairing agent, formed Fab:DS HIP complexes were least soluble in water. Further, nanoparticles (NPs) loaded with drug and Fab:DS HIP complex were prepared and characterised with respect to encapsulation efficiency and size. We observed significant improvement in encapsulation efficiency for Fab:DS HIP complex-loaded nanoparticles. This study demonstrates a novel approach of formulating antibody-loaded nanoparticles which can also be employed for delivery of large antibodies.
Electrospinning and Imaging (2011)

Abstract Polymer processing via electrospinning is a cost effective and scalable method for preparing nanofibers with industrial, electrical, and biomedical applications, particularly tissue engineering and drug delivery. Characterization methods for these fibers include microscopy techniques for vitro surface morphology information, spectroscopy methods to determine in vitro chemical composition, and medical imaging tools for in vivo assessment of morphology and efficacy of implanted material. The focus of this paper is be on recent applications for electrospun nanofibers, in vitro characterization methods, and medical imaging modalities that can be used for in vivo assessment of the fibers, as well as insights in how to adapt existing techniques toward the characterization of electrospun materials.
Noncatalytic chlorination of diphenyl ether (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNoncatalytic chlorination of diphenyl etherWilliam David Watson and Henry E. HennisCite this: J. Org. Chem. 1979, 44, 7, 1155–1158Publication Date (Print):March 1, 1979Publication History Published online1 May 2002Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/jo01321a028https://doi.org/10.1021/jo01321a028research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An efficient and secure data sharing framework using homomorphic encryption in the cloud (2012)

Due to cost-efficiency and less hands-on management, data owners are outsourcing their data to the cloud which can provide access to the data as a service. However, by outsourcing their data to the cloud, the data owners lose control over their data as the cloud provider becomes a third party. At first, encrypting the data by the owner and then exporting it to the cloud seems to be a good approach. However, there is a potential efficiency problem with the outsourced encrypted data when the data owner revokes some of the users' access privileges. An existing solution to this problem is based on symmetric key encryption scheme and so it is not secure when a revoked user rejoins the system with different access privileges to the same data record. In this paper, we propose an efficient and Secure Data Sharing (SDS) framework using homomorphic encryption and proxy re-encryption schemes that prevents the leakage of unauthorized data when a revoked user rejoins the system. Our framework is secure under the security definition of Secure Multi-Party Computation (SMC) and also is a generic approach - any additive homomorphic encryption and proxy re-encryption schemes can be used as the underlying sub-routines. In addition, we also modify our underlying Secure Data Sharing (SDS) framework and present a new solution based on the data distribution technique to prevent the information leakage in the case of collusion between a user and the Cloud Service Provider.