gebhart/patrepeval huggingface dataset:
Cellular RNA synthesis in normal and mengovirus-infected L-929 cells. (1978)

Cellular RNA synthesis was studied in mouse L-929 cells and in these cells infected with mengovirus. RNA polymerases I, II, and III were partially purified and their chromatographic properties were analyzed by DEAE-Sephadex A-25 chromatography. RNA polymerase II was purified from mouse liver and its subunit structure was compared to that of normal and virus-infected L-929 cells by two-dimensional gel electrophoresis. By these criteria, the enzymes from all three sources were identical. The RNA synthetic activities and capacities of chromatins from normal and virus-infected cells were compared under a variety of conditions. The endogenous activity in chromatin from infected cells was inhibited relative to controls but the residual activity responded normally to stimulation by ammonium sulfate, heparin, and Sarkosyl. The template capacity of the chromatins was compared with added RNA polymerase II and by a rifampicin challenge assay utilizing Escherichia coli RNA polymerase. Identical results were obtained in each case. The number of growing RNA chains and the rates of their elongations were determined. The results showed that nuclei and chromatin from infected cells have a smaller number of RNA polymerase II molecules engaged in RNA synthesis than normal cells do but that the active molecules elongate RNA chains at the same rate.
Design and preliminary affective characterization of a novel fabric-based tactile display (2014)

In this work we present a novel wearable haptic system based on an elastic fabric which can be moved forward and backward over the user forearm thus simulating a human caress. The system allows to control both the velocity of the “caress-like” movement, by regulating motor velocity, and the “strength of the caress”, by regulating motor positions and hence the force exerted by the fabric on the user forearm. Along with a description of the mechanical design and control of the system, we also report the preliminary results of psycho-physiological assessment tests performed by six healthy participants. Such an assessment is intended as a preliminary characterization of the device capability of eliciting tactually emotional states in humans using different combinations of velocity and caress strength. The emotional state is expressed in terms of arousal and valence. Moreover, the activation of the autonomic nervous system is also evaluated through the analysis of the electrodermal response (EDR). The main results reveal a statistically significant correlation between the perceived arousal level and the “strength of the caress” and between the perceived valence level and the “velocity of the caress”. Moreover, we found that phasic EDR is able to discern between pleasant and unpleasant stimuli. These preliminary results are very encouraging and confirm the effectiveness of this device in conveying emotional-like haptic stimuli in a controllable and wearable fashion.
8.01% CuInGaSe2 solar cells fabricated by air-stable low-cost inks (2012)

CuInGaSe(2) (CIGS), a promising thin film solar cell material, has gained lots of attention in decades due to its high energy conversion efficiency and potential lower manufacture cost over conventional Si solar cells. As a cheaper processing method compared to vacuum-based techniques, solution-based deposition has been successfully applied to fabricate electronic devices, such as transistors and solar cells. In this paper, we reported CIGS thin film solar cells with an energy conversion efficiency reaching up to 8.01% using air-stable, low-cost inks. The newly developed inks consist of commercially available, low-cost compounds and solvents and can be processed using a variety of printing and coating techniques. More importantly, the inks can produce CIGS films free of copper selenides and amorphous carbon, two common by-products from solution-based CIGS processes. The mechanism for the transformation from metal salt precursor films to CIGS absorber thin films and the influence of selenium vapour pressure on absorber film quality and photovoltaic device performance were investigated and discussed. High-quality CIGS films with micrometer-sized crystals were obtained by using higher selenization partial pressure.
A novel pulse-based modulation technique for wideband low power communication with neuroprosthetic devices. (2010)

Pulse Harmonic Modulation (PHM) is a novel pulse-based (carrierless) modulation method for wideband, low power data transmission across inductive telemetry links that operate in the near-field domain. PHM utilizes two or more unidentical pulses during each bit period to minimize inter-symbol interference (ISI). In this paper, we describe the PHM concept and demonstrate its operation with a proof-of-concept prototype, which achieves a data rate of 5.2 Mbps at 1 cm coil separation with a bit error rate (BER) of 10−6.
The two-step vacuum-microwave method for histoprocessing. (1995)

When microwaving and vacuum is combined, decrease of boiling temperature can be exploited in the histoprocessing procedures allowing a completely novel approach for impregnating tissue with paraffin. We found that, if the pressure is sufficiently low in the paraffin step, no ethyl-alcohol step is necessary for the dehydration. In that case, the fixed tissue blocks can be directly placed into the isopropanol and, after that, in the hot paraffin, in which the final dehydration of the tissue takes place. The full histoprocessing procedure can thus be shortened into two steps only, with a processing time (for 72 biopsies) of a mere 40 min. Working completely without ethyl alcohol might be of interest for countries in which ethyl alcohol is difficult or expensive to obtain. We conclude that vacuum-microwave histoprocessing allows us to omit ethyl-alcohol dehydration and to replace xylene, resulting in a two-step 'green' (ecological) method.
3D and 4D modeling for design and construction coordination: issues and lessons learned (2007)

The colostomy opening is a very rare site of the large bowel cancer. There is only one case report in the world literature and none in the Hungarian one. The authors report a case of a 51 year old man, who presented a typical malignant growth in his colostomy opening, created 24 years before due to a rectal lesion considered as an inoperable cancer, though not proved histologically. Later the patient was treated by telecobalt irradiation, and the growth perfectly disappeared. Now the second, metachron malignancy arising from the colostomy has been removed and the patient is symptom free four years after the operation. Emphasizing the importance of postoperative follow-up in cases of gastrointestinal malignancies the authors considered this case as an unique but instructive one.
Ti-doped sapphire: tunable solid-state laser (1982)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Peter Moulton, "Ti-doped sapphire: tunable solid-state laser," Optics News 8(6), 9-9 (1982) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Successful molecular dynamics simulation of two zinc complexes bridged by a hydroxide in phosphotriesterase using the cationic dummy atom method (2001)

I report herein two 2.0 ns (1.0 fs time step) MD simulations of two zinc complexes bridged by a hydroxide in phosphotriesterase (PTE) employing the nonbonded method and the cationic dummy atom method that uses virtual atoms to impose orientational requirement for zinc ligands. The cationic dummy atom method was able to simulate the four-ligand coordination of the two zinc complexes in PTE. The distance (3.39 +/- 0.07A) between two nearby zinc ions in the time-average structure of PTE derived from the MD simulation using the cationic dummy atoms matched that in the X-ray structure (3.31 +/- 0.001A). Unequivocally, the time-average structure of PTE was able to fit into the experimentally determined difference electron density map of the corresponding X-ray structure. The results demonstrate the practicality of the cationic dummy atom method for MD simulations of zinc proteins bound with multiple zinc ions. In contrast, a 2.0 ns (1.0 fs time step) MD simulation using the nonbonded method revealed a striking difference in the active site between the X-ray structure and the time-average structure that was unable to fit into the density map of PTE. The results suggest that caution should be used in the MD simulations using the nonbonded method.
Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysis (2001)

Our surveillance policy of patients with LC requires a large number of resources and offers little benefit in terms of patient survival. The decision whether to adopt a surveillance policy towards HCC should rely on the prevalence of the disease in the population and on the resources of a particular country.
TrafficVision: A Case for Pushing Software Defined Networks to Wireless Edges (2016)

In wireless network edges, knowing the network flow types and applications can enable various policy-driven network managements (i.e. traffic offloading, BYOD, E2E QoS etc.). However, applying network policies at wireless links between the mobile devices and access points (APs) requires greater visibility and control on generated traffic generated from mobile devices. The recent advent of Software-Defined Networking (SDN) could enable fine-grained network management at the edge. However, in existing solutions, SDN uses external Deep-Packet Inspection (DPI) engine that requires additional and potentially heavy loaded computational resources to perform the packet analysis. Moreover, mobile applications become more dynamic (rapid install/update), diverse and complex (individual applications generate multiple traffic types) in which scalability and granularity requirements challenging current DPI solutions. In addition, DPI is unreliable in classifying application's encrypted packets. Therefore, in this paper we present the design and the development of TrafficVision that extends the SDN's layer architecture to have fine-grained and real-time policy making at wireless network edges. More specifically, we carefully extends the SDN framework to develop tools that allow to have scalable, efficient and flexible way to classify the network traffic flows at fine-grained fashion using Machine-Learning (ML) based technique. We evaluate our system using the performance of CPU utilization, network overhead and network throughput metrics. Finally, as a proof of concept, we develop a simple case study of traffic management application that exploits TrafficVision.
The Influence of Different Intravascular Volume Replacement Regimens on Renal Function in the Elderly (1999)

We studied the influence of three different intravascular volume replacement regimens on renal function in elderly patients without renal dysfunction who were undergoing major abdominal surgery. Two hydroxyethyl starch and one gelatin preparation were administered perioperatively to maintain stable hemodynamics. As assessed by sensitive markers of renal function, all three regimens can be used safely for volume replacement without risking significant renal dysfunction.
Polarimetric Radar Barcode: A Novel Chipless RFID Concept With High Data Capacity and Ultimate Tag Robustness (2016)

This paper presents a novel chipless radio frequency identification (RFID) concept where the information is encoded on the tag with a 2-D polarimetric radar barcode. We achieved a data capacity with this technique that is outstanding for chipless RFID. Even though these chipless RFID tags are simple, they are extremely robust in harsh environments. The polarimetric radar barcode is formed by a set of geometric structures like small dihedral mirrors, plane surface elements, or dipole elements with different polarimetric backscattering behaviors. These structures are arranged in a 2-D array to create a specific polarimetric 2-D radar barcode. The information is read by polarimetric millimeter-wave imaging radar. The lateral resolution of the radar determines the minimum resolvable element size and is therefore critical for the maximum data capacity of the tag. We show that, theoretically, a data capacity of more than 800 bit on a surface less than the size of a credit card can be achieved if a millimeter-wave multiple-input multiple-output radar is used as reader. The polarimetric encoded reflectors can be formed by metal or reflecting ceramic structures, and the tag can consist of a single material. Thus, tag robustness is limited only by the robustness and temperature resistance of the material used. We verify the performance and functionality of the proposed chipless RFID concept with measurements taken in a laboratory test setup with a 20-bit tag and a millimeter-wave radar system with 77.5-GHz center frequency.
Active microelectronic chip devices which utilize controlled electrophoretic fields for multiplex DNA hybridization and other genomic applications (2000)

Microelectronic DNA chip devices that contain planar arrays of microelectrodes have been developed for multiplex DNA hybridization and a variety of genomic research and DNA diagnostic applications. These devices are able to produce almost any desired electric field configuration on their surface. This ability to produce well-defined electric fields allows charged molecules (DNA, RNA, proteins, enzymes, antibodies, nanobeads, and even micron scale semiconductor devices) to be electrophoretically transported to or from any microlocation on the planar surface of the device. Of key importance to the device function is the permeation layer which overcoats the microelectrodes. The permeation layer is generally a porous hydrogel material that allows water molecules and small ions (Na+, CI-, etc.) to freely contact the microelectrode surface, but impedes the transport of the larger analytes (oligonucleotides, DNA, RNA, proteins, etc.). The permeation layer prevents the destruction of DNA at the active microelectrode surface, ameliorates the adverse effects of electrolysis products on the sensitive hybridization reactions, and serves as a porous support structure for attaching DNA probes and other molecules to the array. In order to maintain rapid transport of DNA molecules, facilitate hybridization, and work within constrained current and voltage ranges, low conductance buffers and various electronic pulsing scenarios have also been developed. These active microelectronic array devices allow electrophoretic fields to be used to carry out accelerated DNA hybridization reactions and to improve selectivity for single nucleotide polymorphism (SNP), short tandem repeat (STR), and point mutation analysis.
Enhancement of Ninhydrin‐ or DFO‐Treated Latent Fingerprints on Thermal Paper (2007)

A new method for enhancement of ninhydrin or 1,8-diazafluoren-9-one (DFO)-treated latent fingerprints on thermal paper will be described. Most thermosensitive surfaces of thermal paper become dark when treated with DFO or ninhydrin petroleum ether (NPB) solution. This effect minimizes contrast between the developed fingerprints and the background. The new method described reduces this dark staining without removing the thermosensitive layer and parts of the developed fingerprints, as occurs with acetone washing. Through the new method, the developed fingerprints appear in sharp lines and high contrast. Extensive tests were performed, leading to an optimized working solution, which charges the paper with a minimum of chemicals, is cheap, and enables a large quantity of papers to be treated in a short time. The working solution contains commercially available, nonvolatile, nitrogenous organic compounds and can be used like the application of NPB solution by dipping.
Complication Rate of the Fascia Closure Technique in Endovascular Aneurysm Repair (2012)

The fascia closure technique during EVAR is safe and has few complications. The low frequencies of pseudoaneurysms and other access site complications make the femoral closure technique a durable alternative.
Standardization activity in ITU of extending 16-kbit/s LD-CELP for personal communication systems (2002)

This paper introduces the standardization activity in ITU-T (International Telecommunication Union, Telecommunication Standardization Sector) of extending 16-kbit/s LD-CELP (low-delay code-excited linear-predictive) speech coding for personal communication systems. ITU-T Recommendation G.728 (LD-CELP) provides toll quality at 16 kbit/s with very low algorithmic delay time (0.625 ms). However, its quality significantly falls under conditions when-the received codewords are lost for 10 to 100 ms that tend to occur in radio channels. The extension of LD-CELP consists of the decoder modification proposed by AT&T that conceals the erasure of channel frames. Subjective test results using Japanese speech shows fairly good quality with this concealment for frame-erasure conditions.
A diagonal electrophoretic method for selective purification of methionine peptides (1967)

1. A method is described that selectively purifies methionine peptides from enzymic digests of a protein. The peptides, after paper electrophoresis, are treated on paper with iodoacetamide at acid pH. This specifically converts methionine residues into their sulphonium salts. When the paper is submitted to electrophoresis at right angles to the original direction, the carbamoylmethylmethionine peptides emerge from an undifferentiated diagonal. 2. Heating at neutral pH converts carbamoylmethylmethionine into homoserine and thereby specifically cleaves the peptides. 3. The effect of the modifications on amino acid composition and sequence analyses of the peptides was studied. 4. When the method was applied to a tryptic digest of S-aminoethyl-chymotrypsinogen A, two peptides were selectively purified that had the expected amino acid sequence.
Light‐Tunable Thermosensitivity of Polymer‐Coated Gold Nanoparticles Achieved by Light‐Controlled Molecular Recognition (2011)

Abstract Thermo‐ and photosensitive gold nanoparticles (AuNPs) coated with an azobenzene‐contained P(DMA‐PAPA‐MAEL) copolymer are prepared by ligand exchange reactions. The photoisomerization of azobenzene moiety on the surface of P(DMA‐PAPA‐MAEL)‐coated AuNPs is detected by means of UV‐Vis spectroscopy with the presence or absence of free α ‐cyclodextrin. When subjected to visible and UV light irradiation alternately, P(DMA‐PAPA‐MAEL)‐coated AuNPs in the presence of free α‐CD display a light‐tunable lower critical solution temperature through light‐controlled molecular recognition between the azobenzene moiety on the surface of AuNPs and free α‐CD. magnified image
AUTOPASS: An Automatic Programming System for Computer Controlled Mechanical Assembly (1977)

This paper describes an experimental very high level programming system for computer controlled mechanical assembly, AUTOPASS (AUTOmated Parts ASsembly System). The AUTOPASS language is oriented towards objects and assembly operations, rather than motions of mechanical assembly machines. It is intended to enable the user to concentrate on the overall assembly sequence and to program with English-like statements using names and terminology that are familiar to him. To relate assembly operations to manipulator motions, the AUTOPASS compiler uses an internal representation of the assembly world. This representation consists of a geometric data base generated prior to compilation and updated during compilation; it thus represents the state of the world at each assembly step. The level of the language has been chosen to provide a high degree of assistance to the user without the system's having to perform artificial intelligence type problem solving operations.
Discrete Mathematical Approaches to Graph-Based Traffic Analysis (2014)

Modern cyber defense and anlaytics requires general, formal models of cyber systems. Multi-scale network models are prime candidates for such formalisms, using discrete mathematical methods based in hierarchically-structured directed multigraphs which also include rich sets of labels. An exemplar of an application of such an approach is traffic analysis, that is, observing and analyzing connections between clients, servers, hosts, and actors within IP networks, over time, to identify characteristic or suspicious patterns. Towards that end, NetFlow (or more generically, IPFLOW) data are available from routers and servers which summarize coherent groups of IP packets flowing through the network. In this paper, we consider traffic analysis of Netflow using both basic graph statistics and two new mathematical measures involving labeled degree distributions and time interval overlap measures. We do all of this over the VAST test data set of 96M synthetic Netflow graph edges, against which we can identify characteristic patterns of simulated ground-truth network attacks.
Transforming Growth Factor β1 Signaling via Interaction with Cell Surface Hyal-2 and Recruitment of WWOX/WOX1 (2009)

Transforming growth factor beta (TGF-beta) initiates multiple signal pathways and activates many downstream kinases. Here, we determined that TGF-beta1 bound cell surface hyaluronidase Hyal-2 on microvilli in type II TGF-beta receptor-deficient HCT116 cells, as determined by immunoelectron microscopy. This binding resulted in recruitment of proapoptotic WOX1 (also named WWOX or FOR) and formation of Hyal-2.WOX1 complexes for relocation to the nuclei. TGF-beta1 strengthened the binding of the catalytic domain of Hyal-2 with the N-terminal Tyr-33-phosphorylated WW domain of WOX1, as determined by time lapse fluorescence resonance energy transfer analysis in live cells, co-immunoprecipitation, and yeast two-hybrid domain/domain mapping. In promoter activation assay, ectopic WOX1 or Hyal-2 alone increased the promoter activity driven by Smad. In combination, WOX1 and Hyal-2 dramatically enhanced the promoter activation (8-9-fold increases), which subsequently led to cell death (>95% of promoter-activated cells). TGF-beta1 supports L929 fibroblast growth. In contrast, transiently overexpressed WOX1 and Hyal-2 sensitized L929 to TGF-beta1-induced apoptosis. Together, TGF-beta1 invokes a novel signaling by engaging cell surface Hyal-2 and recruiting WOX1 for regulating the activation of Smad-driven promoter, thereby controlling cell growth and death.
Subarray quantization lobe decollimation (1999)

This paper presents a new method for the reduction of quantization lobes produced by beam scan in an array of subarrays. These quantization lobes occur at the grating lobe angles and are decreased by the subarray pattern. It is shown that they can be further reduced by adding a random phase component to each subarray. For two element subarrays the quantization lobes (QL) suppression is roughly 10-12 dB.
Thermal Contact Duplication of Videotape (1971)

A high-speed contact duplicator, capable of making video copies from a standard master tape, using chromium dioxide (CrO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> ) has been developed. A computer program was prepared to investigate the basic characteristics of several thermal duplication systems employing CrO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> tape and laboratory equipment was built to show the feasibility of a dynamic thermal duplication system.