gebhart/patrepeval huggingface dataset:
Development and validation of genic-SSR markers in sesame by RNA-seq (2012)

2,164 genic-SSR markers have been developed in sesame using transcriptome sequencing. 276 of 300 validated primer pairs successfully yielded PCR amplicons in 24 cultivated sesame accessions. These markers increase current SSR marker resources and will greatly benefit genetic diversity, qualitative and quantitative trait mapping and marker-assisted selection studies in sesame.
[Determination of endotoxin in inflammatory rheumatic diseases--the effect of nonsteroidal anti-inflammatory agents on intestinal permeability]. (1989)

We measured the amount of plasma endotoxin in 95 patients with inflammatory rheumatic diseases (42 with ankylosing spondylitis; 12 with possible ankylosing spondylitis; 41 with rheumatoid arthritis) and in 16 patients with Crohn's disease with a quantitative Limulus assay. Significantly increased mean values were found in inflammatory rheumatic diseases and in Crohn's disease. Between 31% and 50% of the patients had endotoxin values higher than 10 pg/ml--none of the controls had such values. Patients on regular treatment with NSAIDS had higher amounts of endotoxin again. From our results we discuss an intestinal involvement in inflammatory rheumatic diseases. An inflammation of the gut with an increased permeability seems to be responsible for the raised plasma endotoxin levels compared to healthy controls. NSAIDs probably contribute to the increased permeability of the gut.
Proteomic identification and functional characterization of MYH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity (2014)

Histone deacetylase 6 (HDAC6), a predominantly cytoplasmic protein deacetylase, participates in a wide range of cellular processes through its deacetylase activity. However, the diverse functions of HDAC6 cannot be fully elucidated with its known substrates. In an attempt to explore the substrate diversity of HDAC6, we performed quantitative proteomic analyses to monitor changes in the abundance of protein lysine acetylation in response to HDAC6 deficiency. We identified 107 proteins with elevated acetylation in the liver of HDAC6 knockout mice. Three cytoplasmic proteins, including myosin heavy chain 9 (MYH9), heat shock cognate protein 70 (Hsc70), and dnaJ homolog subfamily A member 1 (DNAJA1), were verified to interact with HDAC6. The acetylation levels of these proteins were negatively regulated by HDAC6 both in the mouse liver and in cultured cells. Functional studies reveal that HDAC6-mediated deacetylation modulates the actin-binding ability of MYH9 and the interaction between Hsc70 and DNAJA1. These findings consolidate the notion that HDAC6 serves as a critical regulator of protein acetylation with the capability of coordinating various cellular functions.
Pooled Analysis of the Prognostic and Predictive Effects of <i>KRAS</i> Mutation Status and <i>KRAS</i> Mutation Subtype in Early-Stage Resected Non–Small-Cell Lung Cancer in Four Trials of Adjuvant Chemotherapy (2013)

KRAS mutation status is not significantly prognostic. The potential interaction in patients with codon-13 mutations requires validation. At this time, KRAS status cannot be recommended to select patients with NSCLC for ACT.
A treatment for carpal tunnel syndrome: results of a follow-up study. (1993)

The results of statistical analyses indicate that CTS subjects can be treated and achieve a significant recovery to within normal comparative levels of non-CTS subjects in most subjective and objective measures.
Old song (1931)

Old song Get access M. A. H. M. A. H. Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume CLXI, Issue jul04, 4 July 1931, Page 13, https://doi.org/10.1093/nq/CLXI.jul04.13g Published: 04 July 1931
Smooth and Self‐Similar SiO<sub>2</sub>‐like Films on Polymers Synthesized in Roll‐to‐Roll Atmospheric Pressure‐PECVD for Gas Diffusion Barrier Applications (2010)

Abstract SiO 2 ‐like layers deposited by means of the developed atmospheric pressure glow‐like DBD assisted CVD technology exhibit remarkable film properties, reported for the first time. The films synthesized in a roll‐to‐roll mode on polymeric webs, are as smooth as the substrate, irrespectively of the precursors (TEOS or HMDSO) and reactive gases (N 2 or air) employed. Detailed AFM investigation on film morphology, surface roughness and auto correlation length ( ξ ) show that they are negligibly influenced with thickness and are similar to that of the polymeric substrate, indicating the self‐similar growth of the SiO 2 ‐like layers in AP‐PECVD. The films are uniform with no defects or particle being incorporated during the deposition process. The produced single layers on polymeric substrate show excellent gas barrier performances towards O 2 and H 2 O permeation (OTR: <5 × 10 −3 cm 3 ·m −2 ·day −1 and WVTR: <5 × 10 −3 g·m −2 ·day −1 ). magnified image
A method for EMI evaluation of notebook computer liquid crystal display panels while eliminating the contribution of computer generated EMI (2002)

The radiated emissions from a liquid crystal display (LCD) panel can be the most difficult signals to attenuate in a notebook computer system. This paper describes a method for evaluating notebook computer LCD panels using a reference test setup. The center of this test setup is a circuit that produces the data, clock, and sync signals required to operate the panel in an EMI producing mode. This circuit (comprising of an oscillator, a programmable array logic part, and a line driver) eliminates the need for a notebook computer during testing, allowing for evaluation of only the LCD panel. By evaluating the panel as an individual component, early problem identification can be realized. From this realization, resolution of the EMI problem can be obtained independent of the system in which the LCD panel is installed.
Effective resolution of racemic pirlindole at the preparative scale (1999)

Pirlindole, a racemic antidepressant drug, was recently resolved using the derivatization method coupled with preparative HPLC. In order to improve this technique, the use of amino acid derivatives as chiral derivatizing agents (CDA) was investigated. Among different residues, the (L)-phenylalanine methyl ester was found to be very effective to separate pirlindole enantiomers using a medium pressure liquid chromatographic (MPLC) method. This procedure is better adapted to preparative application than HPLC. Thus, several grams of the pirlindole antipodes were isolated and characterized. These two enantiomers permitted the study of the stereochemical influence at the pharmacological level. Chirality 11:261–266, 1999. © 1999 Wiley-Liss, Inc.
Ocular Neovascularization (1980)

<h3>To the Editor.</h3> —Dr Paul Henkind's main point appears to be that I have erred grievously in not citing his article on ocular neovascularization (<i>Am J Ophthalmol</i>1978;85:287-301). Anyone familiar with the subject of ocular neovascularization knows how vast is the literature on this subject. Had I to cite every available article, my bibliography would have run to many times the length of the article. In fact, I originally submitted to theArchivesan article about four to five times the size of the published article (<i>Arch Ophthalmol</i>1980;98:574), but the reviewer and the chief editor insisted on a drastic reduction in the size of the text and bibliography. Hence, I had to restrict my review of the literature to the most relevant publications only. I am well aware of Dr Henkind's article but consider it, though a good review of ocular neovascularization, not relevant to the hypothesis postulated by
<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>ν</mml:mi><mml:mo>=</mml:mo><mml:mn>5</mml:mn><mml:mo>/</mml:mo><mml:mn>2</mml:mn></mml:math>Fractional Quantum Hall Effect at 10 T: Implications for the Pfaffian State (2010)

We report on the magnetotransport (including tilt fields) around Landau level filling factor nu=5/2 in a high-purity modulation-doped GaAs/AlGaAs quantum well with twice the electron density of standard samples. A quantized 5/2 Hall plateau is observed at B approximately = 10 T, with an activation gap approximately 125 mK; the plateau can persist up to approximately 25 degree tilt field. This finding is discussed in the context of a proposed Moore-Read Pfaffian (or anti-Pfaffian) wave function being a possible ground state at 5/2. The tilt fields induce a background resistance at 5/2 that could be either isotropic or anisotropic, depending simply on the in-plane magnetic field direction with respect to the GaAs crystalline axis. Such data indicate a substantial coupling between the 5/2 collective phases and the GaAs crystal.
Realistic human face rendering for "The Matrix Reloaded" (2005)

The ultimate challenge in photorealistic computer graphics is rendering believable human faces. We are trained to study the human face since birth, so our brains are intimately familiar with every nuance and detail of what human skin is supposed look like. The challenge of rendering human skin is further complicated by some technical issues such as the fact that skin is a highly detailed surface with noticeable features in the order of ~100 microns and the fact that skin is translucent. On The Matrix Reloaded we had to create completely photorealistic renderings for most of the principal actors including Keanu Reeves, Lawrence Fishborne, and Hugo Weaving.
Gas sorption and transport in substituted polycarbonates (1987)

Abstract The effects of molecular structure manipulation of polycarbonates on sorption and transport of various gases were studied using tetramethyl, tetrachloro, and tetrabromo substitutions onto the aromatic rings of bisphenol A polycarbonate. Solubility and permeability measurements were made at 35°C over the pressure range of 1–20 atm for a variety of gases, namely CO 2 , CH 4 , O 2 , N 2 , and He. A threefold to fourfold increase in permeability was caused by the tetramethyl substitution, whereas the tetrachloro and tetrabromo substitutions reduced the permeability relative to the tetramethyl substitution. Lower activation energies for transport were found for the tetramethyl polycarbonate relative to the unsubstituted polycarbonate. Permeability coefficients were factored into solubility and diffusion coefficients. Sorption levels increased for all substitutions, but among the substituted polymers the levels remain practically the same. Solubility data were analyzed in terms of the dual sorption model. The Henry's law solubility coefficients obtained from this analysis were found to be consistent with a predictive equation developed for rubbery polymers. The usual correlation for predicting the Langmuir sorption capacity of the model overestimates the values for the substituted polycarbonates, and a proposal for the cause of this is offered. Thermal expansion of these polymers was measured using dilatometry, and the results are used in the interpretation of the sorption data. Diffusion phenomena are explained by segmental mobility and free volume considerations. The effects of CO 2 exposure history on sorption and transport were also investigated.
Characterization of Plasmodium falciparum sporozoite surface protein 2. (1992)

Immunization of mice with Plasmodium yoelii sporozoite surface protein 2 (PySSP2) and circumsporozoite protein protects completely against P. yoelii. The amino acid sequence of PySSP2 suggested that the thrombospondin-related anonymous protein (TRAP) [Robson, K. J. H., Hall, J. R. S., Jennings, M. W., Harris, T. J. R., Marsh, K., Newbold, C. I., Tate, V. E. & Weatherall, D. J. (1988) Nature (London) 335, 79-82] is the Plasmodium falciparum homolog of PySSP2. We report data confirming that TRAP is P. falciparum SSP2 (PfSSP2). Murine antibodies against recombinant PfSSP2 identify a 90-kDa protein in extracts of P. falciparum sporozoites, recognize sporozoites and infected hepatocytes by immunofluorescence, localize PfSSP2 to the sporozoite micronemes by immunoelectron microscopy and to the surface membrane by live immunofluorescence, and inhibit sporozoite invasion and development in hepatocytes in vitro. Human volunteers immunized with irradiated sporozoites and protected against malaria develop antibody and proliferative T-cell responses to PfSSP2, suggesting that, like PySSP2, PfSSP2 is a target of protective immunity, and supporting inclusion of PfSSP2 in a multicomponent malaria vaccine.
Mesoporous TiO<sub>2</sub> Nanocrystal Clusters for Selective Enrichment of Phosphopeptides (2010)

Protein phosphorylation plays a key role in most cellular processes. Studying phosphopeptides in complex biological samples has been a great challenge due to their low abundance as well as the coexistence of excessive amounts of salts or surfactants. In this work we demonstrate a general approach for selective separation of phosphopeptides using a class of novel mesoporous nanostructured materials. TiO(2) nanocrystals are first self-assembled into submicrometer clusters containing relatively uniform mesoscale pores and then stabilized by coating with a thin layer of silica. Calcination of the materials at high temperatures connects the neighboring nanocrystals together and enhances the mechanical stability of the clusters and at the same time removes the organic surfactants and makes the TiO(2) surface fully accessible to phosphopeptides. By coating the nanocrystal clusters with a layer of silica before calcination and removing it afterward through chemical etching, we have been able to make the cluster surface hydrophilic and negatively charged, thus enhancing the water dispersibility of the clusters and eventually their accessibility to phosphopeptides. The high selectivity and capacity of these mesoporous TiO(2) clusters have been demonstrated by effectively enriching phosphopeptides from digests of phosphoprotein (alpha- or beta-casein), protein mixtures of beta-casein and bovine serum albumin, milk, and human serum samples. We also demonstrate that the self-assembly process brings the flexibility of incorporation of multiple components, such as superparamagnetic nanocrystals, to further facilitate the peptide separation.
Pirfenidone inhibits transforming growth factor-β1-induced fibrogenesis by blocking nuclear translocation of Smads in human retinal pigment epithelial cell line ARPE-19. (2012)

These results collectively provide a rational background for future evaluation of pirfenidone as a potential antifibrotic agent for treating proliferative vitreoretinopathy and other fibrotic retinal disorders.
Glucocorticosteroid action on the immune system: molecular and cellular aspects. (1991)

The history of glucocorticosteroid therapy and modern rheumatology are inseparable. Glucocorticosteroids exert profound effects on the inflammatory and immune responses. They affect the growth, differentiation and function of monocytes and lymphocytes, the distribution of cellular subsets, and the production of cytokines. Glucocorticosteroid-induced lipocortins inhibit eicosanoid production and release by suppressing phospholipase A2. The principal mechanism whereby they exert their powerful effects is through modulation of the transcription of specific sets of genes. Recently, post-transcriptional mechanisms have also been recognized to be affected by glucocorticosteroids. In this review we discuss the molecular and cellular aspects of glucocorticosteroid action on the immune system.
A low-cost Internet of Things (IoT) system for multi-patient ECG's monitoring (2016)

This paper discussed one application of IOT as media data transmission for the electrocardiogram (ECG) signal. We developed ECG monitoring system that can be accessed by several users simultaneously via the internet network. The system consists of ECG hardware, transmission module based on Zigbee and web server for data storage and web application. The ECG signal taken from body's patients is acquired by the ECG machine, and then raw data is sent serially to the computer server using Zigbee. Furthermore, the data can be accessed by other authorized parties via the web pages for the purpose of treatment or consultation. By using this application, patients with heart diseases can interact and consult with a cardiologist anytime and anywhere. The testing result shows that the system can handle up to 20 users without errors. Meanwhile for 50–150 user some errors occurred due to insufficient bandwidth or high data traffic on the server.
An efficient moving object detection and distance measurement algorithm using correlation window (2014)

Moving object extraction and depth perception is one of the complex tasks that restrict the real time suitability of any video surveillance system. This paper presents a new method of extracting any moving object and its depth calculation. A modified background subtraction algorithm is used to detect the moving object. While a correlation window based method is used for solving the correspondence problem. The main proposal of this paper lies in searching a suitable window in the left image that has the least correlation with its neighboring windows which actually reduces the possibility of finding a false corresponding window in the right image. The difference between the positions of the similar windows gives rise of disparity which is later used to calculate the depth. This method shows better result than other existing methods.
Increases in Bone Mineral Density After Discontinuation of Daily Human Parathyroid Hormone and Gonadotropin-Releasing Hormone Analog Administration in Women With Endometriosis (1999)

Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts J Clin Endocrinol Metab 1999;84:1214-1219
Mechanism of CVD Thin Film SnO2 Formation (1978)

The kinetic mechanism of CVD deposition has been studied for (i) reaction at 675°–940°C for and , (ii) reaction at 400°–807°C for and , and (iii) reaction at 425°–578°C for and . In combination with the available literature data, the results of the present investigation have been interpreted to show atomic oxygen as the adsorbed species and tin‐containing gas as the gaseous reactant in both the direct oxidation reactions (Rideal‐Eley mechanism). The hydrolysis reaction is the only thermally unactivated one in the group and proceeds by the collision of molecules on four adsorbed (symmetrically) water molecules on the surface. The open tube cold wall horizontal reactor has been established as an ideal equipment for the kinetic mechanism delineation of all CVD reactions.
Navigator respiratory‐triggered diffusion‐weighted imaging in the follow‐up after hepatic radiofrequency ablation—initial results (2009)

NRT-DWI is useful in the follow-up imaging after RF ablation. ADC-based evaluation of signal alterations adjacent to the ablation zone may contribute to the identification of LTP and nontumoral posttreatment tissue changes.
Flextensional ultrasonic motor using the contour mode of a square piezoelectric plate (2004)

This paper presents the design, fabrication, and characterization of a new type of standing wave piezoelectric ultrasonic motor. The motor uses a metallic flextensional amplifier, or cymbal, to convert the contour mode vibrations of a square piezoelectric ceramic plate into flexural oscillations, which are further converted to produce rotary actuation by means of an elastic-fin friction drive. The motor operates on a single-phase electrical supply. A beryllium copper rotor design with three-fin configuration was adopted, and the geometry was varied to include different material thicknesses, fin lengths, and inclinations. The best stall torque and no load speed for a 25-mm square motor were 0.72 Nmm and 895 r/minute, respectively. The behavior of the stator structure was analyzed by ANSYS finite element software using harmonic and modal analyses. The vibration mode estimated by finite element modeling (FEM) was confirmed by laser Doppler vibration measurements.
Optooptic modulation based on gain saturation (1978)

A technique has been developed for obtaining efficient modulation of an optical signal. It is shown that the presence of a small optical bias signal on an appropriately designed laser amplifier can lead to a substantial change in another much larger signal. The resulting modulators are in many respects the optical analogs of conventional electronic transistors, and several applications are considered.
Remote Sensing of Cirrus Cloud Particle Size and Optical Depth Using Polarimetric Sensor Measurements (2005)

Abstract This paper presents a conceptual approach toward the remote sensing of cirrus cloud particle size and optical depth using the degree of polarization and polarized reflectance associated with the first three Stokes parameters, I, Q, and U, for the 0.865- and 2.25-μm wavelengths. A vector line-by-line equivalent radiative transfer program including the full Stokes parameters based on the adding method was developed. The retrieval algorithm employs the steepest-descent method in the form of a series of numerical iteration procedures to search for the simulated polarization parameters that best match the measured values. Sensitivity studies were performed to investigate the behavior of phase-matrix elements as functions of scattering angles for three ice crystal size–shape combinations. Overall, each phase-matrix element shows some sensitivity toward ice crystal shape, size, and surface roughness due to the various optical effects. Synthetic analysis reveals that the retrieval algorithm is highly accurate, while polarimetric and radiometric error sources cause very small retrieval errors. Finally, an illustrative example of applying the retrieval algorithm to airborne Polarization and Directionality of the Earth’s Reflectances (POLDER) data during the European Cloud and Radiation Experiment (EUCREX) is presented.
Monoclonal antibody affinity purification of a Leishmania membrane glycoprotein and its inhibition of leishmania-macrophage binding. (1986)

Specific monoclonal antibody coupled to Affi-Gel 10 was used to purify a major membrane glycoprotein of Leishmania mexicana amazonensis, one of a group of parasitic protozoa that specifically infect mammalian macrophages. Immobilized antigen was eluted at a 34% efficiency with buffers at either pH 2.5 or 11 or with MgCl2, but only the antigen eluted under basic conditions could be readsorbed to the immunobeads. Sephacryl S-300 gel filtration of the purified antigen gave a single peak of protein estimated to have a molecular mass of 400 kDa. However, NaDodSO4/polyacrylamide gel electrophoresis showed a single band of this protein with an apparent molecular mass of 63 kDa. The antigen is an N-linked glycoprotein, as indicated by its increase in electrophoretic mobility after treatment with endoglycosidase H and by its binding to lentil lectin-Sepharose, elutable with methyl alpha-D-mannoside and methyl alpha-D-glucoside. Purified antigen inhibits the binding of leishmania cells to macrophages by 50%, suggesting that it may play a role in the process of infection.
Novel <i>FLT3</i> point mutations within exon  14 found in patients with acute myeloid leukaemia (2004)

Internal tandem duplications in FLT3 are the most common mutation in acute myeloid leukaemia (AML), with agarose gel electrophoresis of polymerase chain reaction products (PCR/agarose) being the screening method of choice for these mutations. As PCR/agarose screening does not detect small mutations, single-stranded conformational polymorphism analyses (PCR/SSCP) were used in an attempt to identify previously unrecognized point mutations in FLT3 exons 14 and 15 of 140 AML patients, using newly designed primers that anneal within intron sequences. Novel missense point mutations were found in exon 14, suggesting additional investigations should be performed in AML and other haematopoietic malignancies, using this sensitive technique.