gebhart/patrepeval huggingface dataset:
3DVLSI with CoolCube process: An alternative path to scaling (2015)

3D VLSI with a CoolCube™ integration allows vertically stacking several layers of devices with a unique connecting via density above a million/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . This results in increased density with no extra cost associated to transistor scaling, while benefiting from gains in power and performance thanks to wire-length reduction. CoolCube™ technology leads to high performance top transistors with Thermal Budgets (TB) compatible with bottom MOSFET integrity. Key enablers are the dopant activation by Solid Phase Epitaxy (SPE) or nanosecond laser anneal, low temperature epitaxy, low k spacers and direct bonding. New data on the maximal TB bottom MOSFET can withstand (with high temperatures but short durations) offer new opportunities for top MOSFET process optimization.
A limited-interconnect synthetic neural IC (1988)

A report is presented of the first design and simulation of a limited-interconnect, multilayered perceptron-like network. The network is isomorphic to fully connected layered architectures, but satisfies the interconnection length and density constraints imposed by VLSI technology. The authors show simulations that illustrate the ability of the architecture to generalize and tolerate faults. A very compact analog neural cell is described that can be fabricated on a production DRAM line. This chip architecture allows dynamic storage of weights, shunting inhibition, and pipelined behavior, and it readily scales to very large numbers of processing elements. A 512-element, feedforward neural chip is described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Localization of Glucose Oxidase and Catalase Activities in <i>Aspergillus niger</i> (1992)

The subcellular localization of glucose oxidase (EC 1.1.3.4) in Aspergillus niger N400 (CBS 120.49) was investigated by (immuno)cytochemical methods. By these methods, the bulk of the enzyme was found to be localized in the cell wall. In addition, four different catalases (EC 1.11.1.6) were demonstrated by nondenaturing polyacrylamide gel electrophoresis of crude extracts of induced and noninduced cells. Comparison of both protoplast and mycelial extracts indicated that, of two constitutive catalases, one is located outside the cell membrane whereas the other is intracellular. Parallel with the induction of glucose oxidase, two other catalases are also induced, one located intracellularly and one located extracellularly. Furthermore, lactonase (EC 3.1.1.17) activity, catalyzing the hydrolysis of glucono-delta-lactone to gluconic acid, was found to be exclusively located outside the cell membrane, indicating that gluconate formation in A. niger occurs extracellularly.
A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease (2015)

Roflumilast reduces pulmonary inflammation through decreasing prolyl endopeptidase activity and AcPGP. As expected for lower AcPGP levels, markers of neutrophilic inflammation are blunted. Inhibiting this self-propagating pathway lessens the overall inflammatory burden, which may alter the natural history of COPD, including the risk of exacerbation. Clinical trial registered with www.clinicaltrials.gov (NCT 01572948).
Thin Film Encapsulation of Light-Emitting Diodes with Photopolymerized Polyacrylate and Silver Films (2005)

A thin film encapsulation of organic light-emitting diodes (OLEDs) is investigated with a multi-layer stack of polyacrylate-Ag-polyacrylate-Ag-polyacrylate-Ag-polyacrylate (PAPAPAP). It is shown that the fabrication of polyacrylate films by a wet process does not affect the electroluminescent (EL) characteristics of the devices and polyacrylate films together with the silver layers can perform to minimize oxygen and water diffusion into the organic light-emitting device. The structure of polyacrylate(20 μm)-Ag(200 nm)-polyacrylate(20 μm)-Ag(200 nm)-polyacrylate(20 μm)-Ag(200 nm)-polyacrylate(20 μm) is demonstrated to enhance dramatically the lifetime of OLEDs.
<title>Printing inks containing the photochromic protein bacteriorhodopsin</title> (2000)

The biological photo chrome bacteriorhodopsin occurs in nature in the form of a 2D crystalline lattice. In this form, the so-called purple membranes, it is astonishingly stable towards chemical and thermal degradation. Variants of the naturally occurring bacteriorhodopsin can be switched between a purple and a yellowish state with yellow and blue light - no UV light is required. The application of bacteriorhodopsin in the form of a photochromic ink is described. In addition to the optical effect, which can be checked easily without instrumentation, additional optional security elements can be hidden in the material which are very hard to detect and to copy. Among them is the alteration of the aminoacid sequence of bacteriorhodopsin in positions which do not interact with its photochemical properties. By this and related methods even single production batches may be identified. The price of the material to date is too high for a broad commercial application but current efforts to reduce the production costs by several orders of magnitude look promising.
Some Observations on the Electrolyses of Solutions of Rare-Earth Metal Salts in Basic Solvents (1954)

Article MetricsDownloadsCitationsNo data available.012JulAugSepOctNovDec40Total6 Months12 MonthsTotal number of downloads for the most recent 6 whole calendar months.
[Evaluation of continuous blood pressure monitoring by arterial tonometry in the aged]. (1997)

We compared tonometry systolic pressure with direct systolic pressure in 12 elderly patients (9 patients with sinus rhythm and 3 patients with atrial fibrillation) and 1 young adult patient undergoing surgical procedures in order to evaluate reliability of continuous blood pressure by arterial tonometry. In elderly patients when blood pressure fluctuated, the differences between tonometry systolic pressure and direct systolic pressure were larger compared with when blood pressure was stable. In the elderly with sinus rhythm, the correlation with stable blood pressure was 0.908; while that with fluctuating blood pressure was 0.838. In atrial fibrillation group, the differences between stable blood pressure and fluctuating blood pressure were still larger. The results indicate that it is difficult to use tonometry method as a reliable tool for blood pressure monitoring in geriatric anesthesia under circumstances of fluctuating blood pressure.
Global electromagnetic analysis of microwave circuits including lumped elements based on iterative method (2004)

This paper proposes an extension of the iterative method for the global electromagnetic analysis of microwave distributed circuits containing passive or active, linear or nonlinear lumped elements which are characterized by their surface impedance. Its validation is performed through the study of a varactor tuned filter.
<i>In vivo</i> Inhibition of Lung Cancer by GRN163L: A Novel Human Telomerase Inhibitor (2005)

Differential regulation of telomerase activity in normal and tumor cells provides a rationale for the design of new classes of telomerase inhibitors. The telomerase enzyme complex presents multiple potential sites for the development of inhibitors. GRN163L, a telomerase enzyme antagonist, is a lipid-modified 13-mer oligonucleotide N3' --> P5'-thio-phosphoramidate, complementary to the template region of telomerase RNA (hTR). We evaluated both the in vitro and in vivo effects of GRN163L using A549-luciferase (A549-Luc) human lung cancer cells expressing a luciferase reporter. GRN163L (1 micromol/L) effectively inhibits telomerase activity of A549-Luc cells, resulting in progressive telomere shortening. GRN163L treatment also reduces colony formation in soft agar assays. Surprisingly, after only 1 week of treatment with GRN163L, A549-Luc cells were unable to form robust colonies in the clonal efficiency assay, whereas the mismatch control compound had no effect. Finally, we show that in vivo treatment with GRN163L is effective in preventing lung metastases in xenograft animal models. These in vitro and in vivo data support the development of GRN163L as a therapeutic for the treatment of cancer.
Parallel Stitching of 2D Materials (2016)

Diverse parallel stitched 2D heterostructures, including metal-semiconductor, semiconductor-semiconductor, and insulator-semiconductor, are synthesized directly through selective "sowing" of aromatic molecules as the seeds in the chemical vapor deposition (CVD) method. The methodology enables the large-scale fabrication of lateral heterostructures, which offers tremendous potential for its application in integrated circuits.
An intelligent approach to handling imperfect information in concept-based natural language queries (2002)

Missing information, imprecision, inconsistency, vagueness, uncertainty, and ignorance abound in information systems. Such imperfection is a fact of life in database systems. Although these problems are widely studied in relational database systems, this is not the case in conceptual query systems. And yet, concept-based query languages have been proposed and some are already commercial products. It is therefore imperative to study these problems in concept-based query languages, with a view to prescribing formal approaches to dealing with the problems. In this article, we have done just that for a concept-based natural language query system that we developed. A methodology for handling and resolving each type of imperfection is developed. The proposed approaches are automated as much as possible, with the user mainly serving an assistive function.
Molecular characterization of <i>hpuAB</i>, the haemoglobin–haptoglobin‐utilization operon of <i>Neisseria meningitidis</i> (1997)

We previously identified HpuB, an 85 kDa Fe-repressible protein required for utilization of Fe from, and binding to, haemoglobin and the haemoglobin-haptoglobin complex. The gene for hpuB was cloned from Neisseria meningitidis strain DNM2 and the predicted amino acid sequence indicates that HpuB is an outer membrane receptor belonging to the TonB family of high-affinity transport proteins. A second open reading frame, predicted to encode a 34.8 kDa lipoprotein, was discovered 5' to hpuB, and was designated hpuA. HpuA was identified in a total-membrane-protein preparation by construction of a mutant lacking HpuA. Acylation of HpuA was confirmed by [3H]-palmitic acid labelling of meningococci. Consensus promoter sequences were not apparent 5' to hpuB. The hpuA insertion mutation exerted a polar effect, abolishing expression of hpuB, suggesting that hpuA and hpuB are co-transcribed. The 3.5 kb polycistronic hpuAB mRNA was identified and shown to be transcriptionally repressed by iron. The transcriptional start site was identified 33 nucleotides 5' to the hpuA translational start site, appropriately positioned around consensus promoter and ferric uptake regulator (Fur)-box sequences. The structure of this operon suggests that HpuA-HpuB is a two-component receptor analogous to the bipartite transferrin receptor TbpB-TbpA.
Early Recognition of Cutaneous Melanoma (1979)

Criteria for the early recognition of malignant melanoma include appreciation of variegation in color and irregularity of lesion border and pigment pattern. Application of these criteria should result in the diagnosis of cutaneous melanoma in its premetastatic surgically curable phase.
The Chemical Process Industries (Shreve, R. Norris) (1945)

ADVERTISEMENT RETURN TO ISSUEPREVBook and Media Revie...Book and Media ReviewNEXTThe Chemical Process Industries (Shreve, R. Norris)Barnett F. Dodge Cite this: J. Chem. Educ. 1945, 22, 9, 467Publication Date (Print):September 1, 1945Publication History Received3 August 2009Published online1 September 1945Published inissue 1 September 1945https://doi.org/10.1021/ed022p467.3RIGHTS & PERMISSIONSArticle Views5500Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Dihydrotestosterone inhibits murine hair growth via the androgen receptor (2008)

Androgens inhibit hair growth in mice, and this inhibition might be caused by androgen-androgen receptor signals.
Altered Expression of Fibroblast Growth Factor Receptors in Human Pituitary Adenomas (1997)

We have shown that basic fibroblast growth factor (FGF) is heterogeneously expressed by human pituitary adenomas and may be implicated as a growth stimulus for these tumors. There are four mammalian FGF receptor (FGFR) genes encoding a complex family of transmembrane tyrosine kinases. The prototypic receptor is composed of three Ig-like extracellular ligand-binding domains, a transmembrane domain, and a cytoplasmic split tyrosine kinase. Multiple forms of cell-bound or secretable isoforms of FGFR-1, -2, and -3 can be generated by cell- and tissue-specific alternative splicing, resulting in tissue-specific FGF function. Shifts in isoform expression accompany tumor progression in some systems. We examined the normal human adenohypophysis and 40 pituitary adenomas to determine the pattern of FGFR expression by reverse transcription-PCR; all tumors were characterized clinically and morphologically. Ribonucleic acid (RNA) was extracted from frozen tumor tissue and primers were used to distinguish messenger RNA of the secretable first Ig-like domain (I) and those of the transmembrane and kinase domains (K) of each FGFR subtype. The normal pituitary-expressed mRNAs for FGFR-1 I and K, FGFR-2 I and K, FGFR-3 I and K, and FGFR-4 I but not FGFR-4 K; this represents the first report of a truncated isoform of FGFR-4, indicating possible alternative polyadenylation sites in this receptor. Only 3 tumors had the same pattern of expression of the 4 FGFRs as the normal gland. Although all tumors expressed FGFR-1 I, 1 tumor did not express FGFR-1 K, suggesting the production of only a secretable form of FGFR-1 by this tumor. Four tumors were negative for FGFR-2 I and K; 6 expressed the secretable form only, and 17 expressed FGFR-2 K but not I. All tumors expressed FGFR-3 I; 14 had secretable forms only, and no tumors expressed FGFR-3 K alone. As in the normal gland, 13 tumors expressed only the secretable I form of FGFR-4. Unlike the normal pituitary, however, 22 expressed FGFR-4 I and K, indicating a possible tumor-specific transmembrane receptor. Five tumors were negative for FGFR-4 I and K. Expression of FGFR proteins was confirmed by immunohistochemical localization of the C-terminal portion of FGFR-1, -2, -3, and -4; the results correlated with the RNA data in each case. There was no correlation between tumor type, size, or aggressiveness and the expression pattern of FGFRs. Our study suggests that pituitary adenomas have altered FGFR subtype and isoform expression, which may determine their hormonal and proliferative responses to FGFs.
Ocular Rigidity, Ocular Pulse Amplitude, and Pulsatile Ocular Blood Flow: The Effect of Intraocular Pressure (2009)

The present results suggest a nonlinear pressure-volume relation in the living human eye characterized by an increase in rigidity at higher IOP levels. The increased OPA and decreased pulse volume relate to the decreased POBF and the increased mechanical resistance of the ocular wall at high IOP levels.
Turnover of muscle protein in the fowl. Collagen content and turnover in cardiac and skeletal muscles of the adult fowl and the changes during stretch-induced growth (1978)

The collagen content and the rate of collagen synthesis were measured in the anterior and posterior latissimus dorsi muscles and in heart from fully grown fowl. This was done by measuring the proline/hydroxyproline ratios in the muscle and by a constant infusion of [(14)C]proline. These measurements were also made during the hypertrophy of the anterior muscle in response to the attachment of a weight to one wing of the fowl. In the non-growing muscles the collagen content was higher in the anterior muscle (22.8% of total protein) than in the posterior muscle (9.5% of total protein) and lowest in the heart (3.8% of total protein). In the two skeletal muscles a little over half of the collagen was accounted for by internal collagen (i.e. perimysium and endomysium). Collagen synthesis in these non-growing muscles occurred at 0.59%/day in each of the two skeletal muscles and at 0.88%/day in the cardiac muscle. During hypertrophy the collagen content of the anterior muscle increased, but not as fast as intracellular protein, so that after 58 days the concentration had fallen from 22.8 to 14.4% of total protein. This may have resulted from an incomplete production of the epimysial sheath, since the concentration of internal collagen did not fall and as a result accounted for over 80% of the total in the enlarged muscle. Collagen synthesis increased 8-fold during the first week of the hypertrophy, but never amounted to more than 4% of the total muscle protein synthesis. When the net accumulation of collagen is compared with the increased rate of synthesis it is concluded that between 30 and 70% of the newly synthesized collagen may have been degraded.
LOW VELOCITY IMPACT RESPONSE OF A LAMINATED COMPOSITE TUBE WITH A METALLIC BUMPER LAYER (2006)

A thin metallic sheet was bonded to the outer surface of a laminated composite curved beam as a bumper layer. It was believed that a metallic bumper layer such as an aluminum thin sheet would be able to intercept any lateral impacting force and absorb impact energy through plastic deformation. Since aluminum is comparatively light weight, a thin sheet will not result in a significant increase in structural weight. Results showed that impact damage occurred primarily in the bumper layer, thereby resulting in a much higher residual bending strength compared to the control specimen.
[Chemosensitivity prediction in tumor cells ex vivo--difficulties and limitations of the method]. (2008)

Certain hope is entertained in the prediction of chemosensitivity in vitro/ ex vivo for the purpose of selecting the most effective treatment of malignant diseases with minimal patient loading. The possible choice of an effective substance based on the results of a simple ex vivo test would increase the success of the treatment in case of standard chemotherapy failure or in the treatment of primary chemoresistant tumor. MTT test seems to be an easy process for the prediction of chemosensitivity of isolated malignant cells ex vivo, however each method represents a simple tool, which can provide false results if incorrectly preformed. Numerous limitations significantly reduce the successful evaluation and constituent aspects of the methodic press to further reflections about the proper application of the test.
Compact full C-band tunable filters for 50 GHz channel spacing based on high order micro-ring resonators (2004)

Full C-band tunable filters for 50 GHz channel spacings based on 5/sup th/ order micro-ring resonator filters are described. These filters are tunable over 40 nm and can accommodate one hundred 50 GHz channels.
Car transportation system grasping two drive wheels (2012)

This article describes the concept of a novel car transportation system including two mobile robots with a lift mechanism for single wheel. The system lifts only two drive wheels of a front-wheel-drive vehicle or a rear-wheel-drive vehicle, and transports them. However, the system has nonholonomic constraints because all wheels of a vehicle are not lifted by the system. This article also describes a motion control method and a vehicle's wheelbase estimate algorithm for the proposed system in order to maneuver the vehicle. The motion control method is based on control theory for a three-wheeled cycle system. On the other hand, the vehicle's wheelbase estimate algorithm includes impedance control, and the system estimates the vehicle's wheelbase from constraint forces during transporting the vehicle. Finally, two experiments show that the proposed system can maneuver the vehicle.
A new scheme of layered coding of stereoscopic video (2010)

A new scheme of layered coding of stereoscopic video based on the correlation of motion vector fields (MV fields) is proposed in this paper, in which the bit streams robustness is improved to error channel and the coding efficiency is not reduced evidently. In our proposed scheme, the stereoscopic video is classified into one base layer and two enhancement layers. First, left-view video is encoded as Base Layer to ensure the basic quality of two-dimensional video. Then, the disparity vectors (DVs) of right-view video are encoded as Enhancement Layer 1. To lower bit rates further and reduce the network load, the strong correlation of the motion vectors (MVs) for two views video sequence are tested. Based on the correlation of MVs between views, the MVs of right-view are transmitted as Enhancement Layer 2 only if the correlation between left and right view is less than some threshold. Experimental results are demonstrated to testify the efficiency of our proposed scheme.
Authorship and Sources of Gentleness and Nobility, A Study in Early Tudor Drama (1942)

Other| March 01 1942 Authorship and Sources of Gentleness and Nobility, A Study in Early Tudor Drama Walter Cameron Kenneth. Raleigh, North Carolina: The Thistle Press, 1941. Pp. 46. $1.25. William Nelson William Nelson Search for other works by this author on: This Site Google Modern Language Quarterly (1942) 3 (1): 129–131. https://doi.org/10.1215/00267929-3-1-129c Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation William Nelson; Authorship and Sources of Gentleness and Nobility, A Study in Early Tudor Drama. Modern Language Quarterly 1 March 1942; 3 (1): 129–131. doi: https://doi.org/10.1215/00267929-3-1-129c Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsModern Language Quarterly Search Advanced Search The text of this article is only available as a PDF. Copyright © 1942 by Duke University Press1942 Article PDF first page preview Close Modal You do not currently have access to this content.