gebhart/patrepeval huggingface dataset:
N<scp>EW</scp> I<scp>NSIGHTS INTO THE</scp> R<scp>EGULATION AND</scp> F<scp>UNCTIONAL</scp> S<scp>IGNIFICANCE OF</scp> L<scp>YSINE</scp> M<scp>ETABOLISM IN</scp> P<scp>LANTS</scp> (2002)

Lysine is one of the most limiting essential amino acids in vegetative foods consumed by humans and livestock. In addition to serving as a building block of proteins, lysine is also a precursor for glutamate, an important signaling amino acid that regulates plant growth and responses to the environment. Recent genetic, molecular, and biochemical evidence suggests that lysine synthesis and catabolism are regulated by novel concerted mechanisms. These include intracellular compartmentalization of enzymes and metabolites, complex transcriptional and posttranscriptional controls of genes encoding enzymes in lysine metabolism during plant growth and development, as well as interactions between different metabolic fluxes. The recent advances in our understanding of the regulation of lysine metabolism in plants may also prove valuable for future production of high-lysine crops.
Phototunable lasing in dye-doped cholesteric liquid crystals (2003)

In this letter, we report the results of phototunable lasing in dye-doped cholesteric liquid crystals (DD–CLC). Photoexcitation of DD–CLC films gives rise to laser emission in the violet-UV range. Control of the structure of the chiral dopant driven by UV phototransformation is exploited in order to obtain a permanent variation of the cholesteric pitch. Laser emission wavelength tuning, by means of photoinduced shifting of the selective reflection band of the cholesteric liquid crystals is established. A tuning interval of about 35 nm, in the wavelength range of 385–415 nm, is observed.
Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules (1986)

Monoclonal antibodies specific for regions of the transforming protein of Abelson murine leukemia virus were prepared. Antibodies directed against the kinase domain inhibited the autophosphorylation of v-abl proteins, and all of the antibodies reacted with the products of the murine and human c-abl loci.
Programming and verifying critical systems by means of the synchronous data-flow language LUSTRE (1991)

article Free Access Share on Programming and verifying critical systems by means of the synchronous data-flow language LUSTRE Authors: Christophe Ratel Merlin-Gerin / SES and IMAG / LGI Merlin-Gerin / SES and IMAG / LGIView Profile , Nicolas Halbwachs IMAG / LGI, Grenoble, France IMAG / LGI, Grenoble, FranceView Profile , Pascal Raymond IMAG / LGI, Grenoble, France IMAG / LGI, Grenoble, FranceView Profile Authors Info & Claims ACM SIGSOFT Software Engineering NotesVolume 16Issue 5Dec. 1991 pp 112–119https://doi.org/10.1145/123041.123062Published:01 September 1991Publication History 23citation394DownloadsMetricsTotal Citations23Total Downloads394Last 12 Months21Last 6 weeks12 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Distribution of antioxidants among blood components and lipoproteins: Significance of lipids/CoQ<sub>10</sub> ratio as a possible marker of increased risk for atherosclerosis (1999)

Total CoQ10 levels were evaluated in whole blood and in plasma obtained from a group of 83 healthy donors. Extraction with light petroleum ether/methanol was more efficient, for whole blood, than the extraction which is often used for plasma and serum, i.e., ethanol hexane. An excellent correlation was present between plasma CoQ10 and whole blood CoQ10. CoQ10 is mainly associated with plasma rather than with cellular components. Positive, significant correlations were found between the LDL-chol/CoQ10 ratio and the total-chol/HDL-chol ratio, which is usually considered a risk factor for atherosclerosis. The proportion of CoQ10 carried by LDL was 58 +/- 10%, while the amount carried by HDL was 26 +/- 8%. In VLDL + IDL CoQ10 was 16 +/- 8%. The content of CoQ10 in single classes of lipoproteins is strictly correlated with CoQ10 plasma concentration. In a parallel study conducted on a population of diabetic patients (one IDDM group and one NIDDM) CoQ10 plasma levels were generally higher compared to the control group, also when normalised to total cholesterol. In particular the LDL fraction showed a CoQ10/chol ratio higher in NIDDM but not in IDDM patients, compared to controls. The CoQ10/triglycerides ratio was lower in NIDDM respect to controls and even lower in IDDM patients.
Surface Plasmon Resonance (SPR) Biosensors in Pharmaceutical Analysis (2014)

This review aims to highlight the applications of one of the most prominent optical biosensor technologies, surface plasmon resonance (SPR), in the drug discovery process and quality analysis of pharmaceutical compounds and their particularities. SPR assay formats and experimental issues are used for pharmacokinetic drug profiling, ADMET studies, high-throughput screening, and fragment-based drug screening, the last with an emphasis on the detection of small (drug) molecules. The classical method strengths and some applications of localized SPR and SPR imaging that are of high interest in the drug discovery process are presented, as well as possible challenges. While similar works treat separately the steps of drug discovery or focus only on the detection of drug residues in food or health safety, this review presents in a compact format the results and the progress obtained in both areas (drug discovery and quality analysis) based on the application of SPR biosensors.
Weight Reduction: Diet and Dishes (1942)

The second edition of this book within four years has been revised and some newer material added, including a table of alcoholic beverages and a short war appendix. The material is written in an entertaining style and is presented in simple, nontechnical language. Some of the foods are limited to the British groups (Allenby's Food, Benger's Food, Bourn-Vita). In part II, 104 pages of detailed recipes are given. The book should be extremely helpful to the intelligent layman seeking to understand his diet, but it is not without interest to the physician. No bibliography is given.
Clinical guidelines and indications for bronchoalveolar lavage (BAL): Report of the European Society of Pneumology Task Group on BAL (1990)

This group report was developed jointly by: U . Costabel (Essen), C . Danel (Paris), L.M. Fabbri (Padova), P.L . Haslam (London), C. Hutter (Vienna) secretary, D. Israel-Biet (Paris), H. Klech (Vienna) chairman, W. Pohl (Vienna) secretary, L.W . Poulter (London), E. Pozzi (Torino), S .I . Rennard (Omaha), V. De Rose (Torino), G.A. Rossi (Genova), M. Rust (Frankfurt), G. Semenzato (Padova), B. Wallaert (Lille) . Edited by H. Klech' and C. Hutter
Generation of ballistic electrons in nanocrystalline porous silicon layers and its application to a solid-state planar luminescent device (2002)

A principle of planar-type visible light emission is presented using ballistic electrons as excitation source. The device is composed of a semitransparent top electrode, a thin film of fluorescent material, a nanocrystalline porous silicon (nc-PS) layer, an n-type silicon wafer, and an ohmic back contact. When a positive dc voltage is applied to the top electrode with respect to the substrate, electrons injected into the nc-PS layer are accelerated via multiple-tunneling through interconnected silicon nanocrystallites, and reach the outer surface as energetic hot or quasiballistic electrons. They directly excite the fluorescent film, and then induce uniform visible luminescence. This solid-state light-emitting device, regarded as a “vacuum-less cathode-ray tube,” has many technological advantages over the conventional luminescent devices. It may lead to big innovations in the development of large-area thin flat-panel display and other electronic devices.
Bone morphogenetic proteins promote cartilage differentiation and protect engineered artificial cartilage from fibroblast invasion and destruction (2002)

Cartilage differentiation and matrix maturation are promoted by BMPs in cartilage engineering. The inhibitory effect of BMP-7 on a nonspecific infiltrative response in immunocompromised nude mice further suggests that individual morphogens not only may contribute to cartilage maturation, but also may protect it from nonspecific inflammation and invasive destruction. These properties advance BMPs as promising tools for engineering of cartilaginous joint bioprostheses and as candidate biologic agents or genes for cartilage stabilization in arthritis.
<title>Survey of digital tape transport servo systems</title> (1996)

As the data storage density continues to grow, high performance tape transports are needed for fine positioning and transport of the media over the read and write heads. This paper presents a survey of digital tape transport servo systems for four popular types of drives: (1) reel to reel drives; (2) single cartridge drives; (3) helical scanning drives; and (4) belt-driven drives. Concepts behind velocity, tension and tracking control employed in production drives are discussed and references to pertinent research cited. Techniques used to measure error in the parameters under servo control are presented.
The evolution of lasers in urology (2011)

The world's first laser was developed by Theodore Maiman in 1960. Over the course of the past five decades, this technology has evolved into a highly specialized entity, also finding a niche market in the field of urology. Lasers obtained from various lasing mediums producing amplified light of different wavelengths have been tested for urological applications. Today, these lasers are most commonly used in the surgical management of benign prostatic hyperplasia and as intracorporeal lithotripters. Other uses include ablation of various urologic tumors and incising strictures of the upper- and lower urinary tract. A continuous process of evolution of this technology is taking place, resulting in surgical lasers becoming ever safer, more effective, and more affordable.
Low‐molecular‐weight human serum proteome using ultrafiltration, isoelectric focusing, and mass spectrometry (2004)

Identification of the serum proteome is a daunting analytical task due to the complex nature of the sample which has an extremely large dynamic range of protein components. This report addresses this issue by using centrifugal ultrafiltration to enrich the low-molecular-weight (LMW) serum proteome while decreasing the amount of abundant high-molecular-weight proteins. Reduction of the complex nature of the sample was achieved by fractionation of the LMW serum proteins using solution-phase isoelectric focusing (IEF). Multiple enzyme digestions are performed and analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Analysis of the tandem mass spectra resulted in the identification of 262 proteins belonging to LMW serum proteome. Our results demonstrate the effectiveness of this methodology to isolate and identify LMW proteins with improved confidence in the MS data acquired. In addition, our methodology can be combined with other multidimensional chromatography techniques performed on the peptide level to increase the number of identified proteins.
Rheological measurements using microcantilevers (2002)

An attempt was made to demonstrate for the first time that the frequency response of microcantilevers can be used to measure the density and viscosity of both gases and liquids. This was achieved by employing the theoretical model of Sader for the frequency response of AFM cantilevers immersed in viscous fluids. Using a single microcantilever, the density and viscosity of both gases and liquids were measured simultaneously. The measured densities and viscosities were compared against published literature values.
Prospective motion correction for magnetic resonance spectroscopy using single camera retro‐grate reflector optical tracking (2011)

Prospective motion correction for 1H-MRS, using single-camera RGR tracking, can reduce spectral artifacts and quantitation errors in Cho/Cr ratios due to head motion and promises improved spectral quality and reproducibility.
Semiconductor Bare Chip ID Recognition Using Combinational Hough Transform. (1999)

An identification number is carved by laser on a semiconductor bare chip for flip-chip-attach assembly. Each digit of an identification number is represented by the inclination of ID bars that are composed of five short lines. This paper proposes a method to recognize an identification number on a bare chip by image processing. The position and angle of orthogonal standard bars that are used to allocate ID bars are recognized by the combinational Hough transform using differences between edge directions of a pair of edge points. Inclinations of ID bars are measured using statistical distribution of edge directions. All identification numbers on 320 bare chips were recognized successfully, and the processing time recorded 0.37 second by an identification number.
Seismic demigration/migration in the curvelet domain (2008)

Abstract Curvelets can represent local plane waves. They efficiently decompose seismic images and possibly imaging operators. We study how curvelets are distorted after demigration followed by migration in a different velocity model. We show that for small local velocity perturbations, the demigration/migration is reduced to a simple morphing of the initial curvelet. The derivation of the expected curvature of the curvelets shows that it is easier to sparsify the demigration/migration operator than the migration operator. An application on a 2D synthetic data set, generated in a smooth heterogeneous velocity model and with a complex reflectivity, demonstrates the usefulness of curvelets to predict what a migrated image would become in a locally different velocity model without the need for remigrating the full input data set. Curvelets are thus well suited to study the sensitivity of a prestack depth-migrated image with respect to the heterogeneous velocity model used for migration.
Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels (2014)

Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been shown to enhance tissue functionality. Bioprinting can be used to precisely position cells and cell-laden materials to generate controlled tissue architecture. Therefore, it represents an exciting alternative for organ fabrication. Despite the rapid progress in the field, the development of printing processes that can be used to fabricate macroscale tissue constructs from ECM-derived hydrogels has remained a challenge. Here we report a strategy for bioprinting of photolabile cell-laden methacrylated gelatin (GelMA) hydrogels. We bioprinted cell-laden GelMA at concentrations ranging from 7 to 15% with varying cell densities and found a direct correlation between printability and the hydrogel mechanical properties. Furthermore, encapsulated HepG2 cells preserved cell viability for at least eight days following the bioprinting process. In summary, this work presents a strategy for direct-write bioprinting of a cell-laden photolabile ECM-derived hydrogel, which may find widespread application for tissue engineering, organ printing and the development of 3D drug discovery platforms.
Insulator-metal transition and giant magnetoresistance in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">La</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mi mathvariant="normal">−</mml:mi><mml:mi mathvariant="italic">x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Sr</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="italic">x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">MnO</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1995)

Insulator-metal phenomena depending on band filling (doping degree), temperature, and external magnetic field have been investigated for prototypical double-exchange ferromagnets, namely, crystals of ${\mathrm{La}}_{1\mathrm{\ensuremath{-}}\mathit{x}}$${\mathrm{Sr}}_{\mathit{x}}$${\mathrm{MnO}}_{3}$ (0\ensuremath{\le}x\ensuremath{\le}0.6). The electronic phase diagram in the plane of the temperature vs nominal hole concentration (x) has been deduced from the magnetic and electrical measurements on the melt-grown crystals. Around the ferromagnetic transition temperature ${\mathit{T}}_{\mathit{C}}$, large negative magnetoresistance was observed. Irrespective of temperature, reduction of the resistivity is scaled with the field-induced magnetization (M) as -\ensuremath{\Delta}\ensuremath{\rho}/\ensuremath{\rho}=C(M/${\mathit{M}}_{\mathit{s}}$${)}^{2}$ for M/${\mathit{M}}_{\mathit{s}}$\ensuremath{\lesssim}0.3, where ${\mathit{M}}_{\mathit{s}}$ is the saturated magnetization. The coefficient C strongly depends on x, i.e., C\ensuremath{\approxeq}4 near the compositional insulator-metal phase boundary (${\mathit{x}}_{\mathit{c}}$\ensuremath{\sim}0.17), but decreases down to \ensuremath{\approxeq}1 for x>=0.4, indicating the critical change of the electronic state.
Associations between Serum 25-hydroxyvitamin D and Consumption Frequencies of Vitamin D Rich Foods in Korean Adults and Older Adults (2014)

Objectives: This study was conducted to investigate the vitamin D status and to determine the association between serum 25-hydroxyvitamin D [25(OH)D] concentrations and consumption frequencies of vitamin D rich foods in Korean adults and older adults. Methods: Subjects were 10,374 adults and 2,792 older adults participating in the 20082009 Korea National Health and Nutrition Examination Survey (KNHANES). Consumption frequencies of vitamin D rich foods were estimated by using a qualitative food frequency questionnaire (FFQ). Eleven food items such as beef, egg, mackerel, tuna, yellow corvina, pollack, anchovy, mushroom, milk, yogurt, and ice cream were selected as vitamin D rich foods based on previous research. Results: The proportions of deficiency (< 12 ng/mL), inadequacy (12-20 ng/mL) and sufficiency (≥ 20 ng/mL) of serum 25(OH)D concentrations from June to November and December to May in adults were 8.8%, 42.3%, 48.8%, and 28.2%, 52.8%, 19.1%, respectively. The proportions of deficiency, inadequacy and sufficiency of serum 25 (OH)D concentrations from June to November and December to May in older adults were 10.1%, 32.4%, 57.5%, and 24.1%, 45.4%, 30.5%, respectively. The mean serum 25(OH)D concentrations in adults were positively related to the consumption frequencies of mackerel, anchovy, all fish, milk and milk·dairy products. The mean serum 25(OH)D concentrations in older adults were positively related to the consumption frequencies of yellow corvina and negatively related to the consumption frequencies of ice cream. Conclusions: Our results suggest that Korean adults were more deficient in serum 25(OH)D concentrations than older adults. The consumption of vitamin D rich foods may affect vitamin D status in Korean adults. Further studies are required to confirm these findings.
Biphenyl Glycosides from the Fruit of <i>Pyracantha </i><i>f</i><i>ortuneana</i> (2006)

Five new biphenyl glycosides, fortuneanosides A (1), B (2), C (3), D (4), and E (5), were isolated from the fruit of Pyracantha fortuneana. Their structures were established as 3,3'-dihydroxy-5'-methoxy-(1,1'-biphenyl)-4-O-beta-d-glucoside, 4'-hydroxy-2,3',5'-trimethoxy-(1,1'-biphenyl)-2'-O-beta-d-glucoside, 4'-hydroxy-3',5'-dimethoxy-(1,1'-biphenyl)-2-O-beta-d-glucoside, 2,4'-dihydroxy-3',5'-dimethoxy-(1,1'-biphenyl)-3-O-beta-d-glucoside, and 3,4'-dihydroxy-3',5'-dimethoxy-(1,1'-biphenyl)-4-O-beta-d-glucoside by spectroscopic analysis. All compounds were evaluated for inhibitory activity against tyrosinase. Compared with arbutin (IC(50) = 0.23 mM), fortuneanoside D possessed more potency, with an IC(50) value of 0.07 mM.
A high-power-density wide-input-voltage-range isolated dc-dc converter having a MultiTrack architecture (2015)

This paper proposes a MultiTrack power conversion architecture that represent a new way of combining switched-capacitor circuits and magnetics. The MultiTrack architecture reduces the voltage ratings on devices, reduces the voltage regulation stress of the system, improves the component utilization, and reduces the sizes of passive components. This architecture is suitable for power conversion applications that require both isolation and wide voltage conversion range. An 18 V to 80 V input, 5 V, 15 A output, 800 kHz, 0.93 inch <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (1/16 brick equivalent) isolated dc-dc converter has been built and tested to verify the effectiveness of this architecture. By utilizing GaN switches, operating at higher frequency, and employing the MultiTrack architecture, the prototype converter achieves a power density of 453 W/inch <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> and a peak efficiency of 91.3%. This power density is 3x higher than the power density of the state-of-the-art commercial converters with comparable efficiency performance across the wide operation range.
Optimization of lattices for quantization (1998)

A training algorithm for the design of lattices for vector quantization is presented. The algorithm uses a steepest descent method to adjust a generator matrix, in the search for a lattice whose Voronoi regions have minimal normalized second moment. The numerical elements of the found generator matrices are interpreted and translated into exact values. Experiments show that the algorithm is stable, in the sense that several independent runs reach equivalent lattices. The obtained lattices reach as low second moments as the best previously reported lattices, or even lower. Specifically, we report lattices in nine and ten dimensions with normalized second moments of 0.0716 and 0.0708, respectively, and nonlattice tessellations in seven and nine dimensions with 0.0727 and 0.0711, which improves on previously known values. The new nine- and ten-dimensional lattices suggest that Conway and Sloane's (1993) conjecture on the duality between the optimal lattices for packing and quantization might be false. A discussion of the application of lattices in vector quantizer design for various sources, uniform and nonuniform, is included.
A TE<sub>1,3</sub> gyrotron at 85 GHz (1985)

A TE<inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,3</inf> gyrotron to operate at 85 GHz with an output power of 300 kW has been designed, fabricated and tested. The device is described and results of the experimentation are given. A comparison to theory is made. Operation at the design frequency was achieved, and preliminary estimates indicate that output powers approaching 300 kW with efficiencies of 43% have been obtained.