gebhart/patrepeval huggingface dataset:
Corona Considerations in Submarine Cable Communications Systems (1974)

Underwater repeatered telephone cable systems are series powered by high-voltage dc. Each repeater and equalizer contains a power separation filter (PSF) for extracting the dc current from the center conductor of the coaxial cable while allowing signal transmission. Corona discharges occurring across the high-voltage components are coupled through reactive components to the repeater's terminals. Each of the experimentally observed pulse shapes emanating from a discharge in the power filter must be evaluated to determine the effect on both system data transmission and reliability objectives. The response to surface corona discharges across the dielectric of the high-voltage capacitors has been successfully duplicated without high voltage by applying current pulses to the appropriate electrodes. This technique in conjunction with artificial contamination of dielectric surfaces and cataloging of the resultant discharge waveforms has led to identification of the major corona sources in the telephone repeater and consequently, to a factory testing program for components and assembled networks that assures satisfactory corona "free" units. The experimental results have also been successfully simulated numerically with a time domain circuit analysis comiputer program which has proved useful in establishing limits for the testing program.
Smart Handoff Scheme for Supporting Roaming between WLAN and GPRS Networks (2005)

Recent advancement in personal communication services (PCS) provides wireless multimedia services for users on the move. For establishing the convenient access environment, the evolution of IP-based integrated scheme becomes very urgent for public wireless access systems. In this paper, we clarify the well-known issues of integrating the general packet radio service (GPRS) network and IEEE 802.11 wireless local area network (WLAN). These issues include the inconsistence in transmission rate and coverage area, the difficulty in seamless handoff, the complexities of mobile IP and address translations, and so on. Based on classified cases, we propose the circular probe strategy (CPS) to solve the IP translations and measure the precise handoff latency of a mobile node roaming from one network to another. This latency information helps a mobile node and its home agent (HA) to decide the appropriate handoff timing, to maximize the data transmission rate, and to perform seamless handoff in the heterogeneous system. We also proposed the smart access point (AP) mechanism to reduce the overhead of CPS and to provide precise handoff latency information for mobile nodes (MNs) to select the most appropriate AP for association. Experiment results demonstrate that the proposed smart handoff scheme performs better than traditional algorithms in terms of handoff time in the integrated network.
Interactive learning of Bayesian Networks using OpenMarkov (2012)

Algorithms for learning Bayesian networks (BNs) behave as a black box that takes a database as an input and returns a network as the output. In contrast, OpenMarkov, our tool for probabilistic graphical models, includes the option to run the algorithms in a step-by-step fashion, presenting a ranked list of operations (such as adding, removing, or inverting links) the user can select, while allowing live edition of the BN throughout the learning process. The application oers some data preprocessing options and the possibility to use a model network to guide the learning process. This functionality in OpenMarkov can be employed to learn BNs with partial expert knowledge, to debug new algorithms, and as a pedagogical tool.
Inhibition of lethal inflammatory responses through the targeting of membrane‐associated Toll‐like receptor 4 signaling complexes with a Smad6‐derived peptide (2015)

We have previously reported that Smad6, one of the inhibitory Smads of transforming growth factor-β (TGF-β)/bone morphogenetic protein (BMP) signaling, inhibits Toll-like receptor (TLR) 4 signaling by disrupting the Pellino-1-mediated TLR4 signaling complex. Here, we developed Smaducin-6, a novel membrane-tethered palmitic acid-conjugated Smad6-derived peptide composed of amino acids 422-441 of Smad6. Smaducin-6 interacted with Pellino-1, located in the inner membrane, thereby disrupting the formation of IRAK1-, RIP1-, IKKε-mediated TLR4 signaling complexes. Systemic administration of Smaducin-6 showed a significant therapeutic effect on mouse TLR4-mediated inflammatory disease models, cecal-ligation-puncture (CLP)-induced sepsis, and lipopolysaccharide-induced endotoxemia, by inhibiting pro-inflammatory cytokine production and apoptosis while enhancing neutrophil migration and bacterial clearance. Our findings provide clues to develop new peptide-based drugs to target Pellino-1 protein in TLR4 signaling pathway for the treatment of sepsis.
Habitar la ciudad, imaginarios y transformaciones de barrio: Caso barrio Alejandro Echavarría, Medellín 1950-2012 (2019)

The purpose of this paper is to approach and reflect on inhabiting the city, especially inhabiting the Alejandro Echavarria neighborhood through social imagery. The approach used was qualitative, on the one hand, review of bibliographic sources and files related to: living, space, neighborhood and imaginary, in addition to the transformation of Medellin and the mega-project of Tranvia-Ayacucho mobility and, on the other hand, Interviews with several inhabitants of the Alejandro Echavarria neighborhood in order to account for their ways of living. The discussion and conclusions focused on neighborhood habitat based on relational imagery as a result of shared experiences, narratives, and spatialities that shaped a binding feeling and significant recognition of domestic-neighborhood life. The transformation of Medellin, as the city providing services, supported by discourses of local government planning (local development plans), and materialized in the Ayacucho Tramway Megaproject, reconfigured the way of inhabiting the Alejandro Echavarria neighborhood towards collective imaginary of mobility, uncertainty and transience.
Leptin's Role in Lipodystrophic and Nonlipodystrophic Insulin-Resistant and Diabetic Individuals (2013)

Leptin is an adipocyte-secreted hormone that has been proposed to regulate energy homeostasis as well as metabolic, reproductive, neuroendocrine, and immune functions. In the context of open-label uncontrolled studies, leptin administration has demonstrated insulin-sensitizing effects in patients with congenital lipodystrophy associated with relative leptin deficiency. Leptin administration has also been shown to decrease central fat mass and improve insulin sensitivity and fasting insulin and glucose levels in HIV-infected patients with highly active antiretroviral therapy (HAART)-induced lipodystrophy, insulin resistance, and leptin deficiency. On the contrary, the effects of leptin treatment in leptin-replete or hyperleptinemic obese individuals with glucose intolerance and diabetes mellitus have been minimal or null, presumably due to leptin tolerance or resistance that impairs leptin action. Similarly, experimental evidence suggests a null or a possibly adverse role of leptin treatment in nonlipodystrophic patients with nonalcoholic fatty liver disease. In this review, we present a description of leptin biology and signaling; we summarize leptin's contribution to glucose metabolism in animals and humans in vitro, ex vivo, and in vivo; and we provide insights into the emerging clinical applications and therapeutic uses of leptin in humans with lipodystrophy and/or diabetes.
Stimulation by organic solvents and detergents of conversion of <scp>L</scp>‐sorbose to <scp>L</scp>‐sorbosone by <i>Gluconobacter melanogenus</i> IFO 3293 (1975)

Treatment of Gluconobacter melanogenus IFO 3293 cells with benzene, carbon tetrachloride, cyclohexane, deoxycholate, toluene, or xylene stimulated their conversion of L-sorbose to L-sorbosone two- to threefold. The degree of stimulation depended upon the length of exposure time to the agent and the age of the G. melanogenus cells. A rapid decrease in viability of the cells and degradation of cell RNA was noted after treatment with the effective agents. The G. melanogenus cells were unable to absorb L-sorbose actively after toluene treatment.
Integrating predictive analysis in self-adaptive pervasive systems (2015)

In this thesis we proposed a proactive self-adaptation by integrating predictive analysis into two phases of the software process. At design time, we propose a predictive modeling process, which includes the activities: define goals, collect data, select model structure, prepare data, build candidate predictive models, training, testing and cross-validation of the candidate models and selection of the ''best'' models based on a measure of model goodness. At runtime, we consume the predictions from the selected predictive models using the running system actual data. Depending on the input data and the time allowed for learning algorithms, we argue that the software system can foresee future possible input variables of the system and adapt proactively in order to accomplish middle and long term goals and requirements.
Acoustic Waveguide Theory Revisited (1993)

The concept of a waveguide as a direct solution to the wave equation was shown to be capable of exact solution, free of the plane wave assumption of Webster'equation. The purpose of the present paper is to revisit the waveguide discussion and to proceed with an exact calculation of the wave propagation in an oblate speroidal waveguide
Isolation and mapping of a polymorphic DNA sequence pMHZ14 on chromosome 1p (D1S60) (1987)

Journal Article Isolation and mapping of a polymorphic DNA sequence pMHZ14 on chromosome 1p (D1S60) Get access M. Hoff, M. Hoff Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Y. Nakamura, Y. Nakamura Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar S. Gillilan, S. Gillilan Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar P. O'Connell, P. O'Connell Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Leppert, M. Leppert Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar G.M. Lathrop, G.M. Lathrop Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar J.-M. Lalouel, J.-M. Lalouel Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar R. White R. White Howard Hughes Medical Institute, University of Utah School of MedicineSalt Lake City, UT 84132, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 15, Issue 22, 25 November 1987, Page 9619, https://doi.org/10.1093/nar/15.22.9619 Published: 25 November 1987
Effects of training and detraining on the static and dynamic balance in elderly fallers and non-fallers: A pilot study (2006)

The absence of stimulation before the trained period shows a negative effect of ageing on walking and falls whereas training permits an improvement in static balance and the pattern of walking under single and dual task conditions, which could be due to an increase in muscular strength and a better division of attention. On the other hand, 3 months of detraining inhibited the effects of training, which showed the speed of the decline caused by 'natural' ageing.
A microbial fuel cell equipped with a biocathode for organic removal and denitrification (2008)

Microbial fuel cells (MFCs) are a promising anaerobic technology but they are limited by the high cost of the catalyst used at the cathode (typically platinum). In this study, we designed a novel type of two-chambered MFC wherein an autoheterotrophic denitrifying biofilm replaced the costly catalyst on the cathode surface. Micro-organisms performed denitrification by using electrons supplied by bacteria oxidizing domestic wastewater and acetate as substrates in the anode chamber. This two-chambered MFC equipped with a biocathode generated during more than 1.5 month up to 9.4 mW m(-2) of anode surface or 0.19 W m(-3) of anode chamber volume, while removing over 65% of COD, 84% of total nitrogen and nearly 30% of suspended solids with domestic wastewater as a substrate, and nearly 95% of acetate in the subsequent experiments.
I of the Vortex: From Neurons to Self (2000)

A highly original theory of how the mind-brain works, based on the author's study of single neuronal cells. In I of the Vortex, Rodolfo Llinas, a founding father of modern brain science, presents an original view of the evolution and nature of mind. According to Llinas, the mindness evolved to allow predictive interactions between mobile creatures and their environment. He illustrates the early evolution of mind through a primitive animal called the squirt. The mobile larval form has a brainlike ganglion that receives sensory information about the surrounding environment. As an adult, the sea squirt attaches itself to a stationary object and then digests most of its own brain. This suggests that the nervous system evolved to allow active movement in animals. To move through the environment safely, a creature must anticipate the outcome of each movement on the basis of incoming sensory data. Thus the capacity to predict is most likely the ultimate brain function. One could even say that Self is the centralization of prediction. At the heart of Llinas's theory is the concept of oscillation. Many neurons possess electrical activity, manifested as oscillating variations in the minute voltages across the cell membrane. On the crests of these oscillations occur larger electrical events that are the basis for neuron-to-neuron communication. Like cicadas chirping in unison, a group of neurons oscillating in phase can resonate with a distant group of neurons. This simultaneity of neuronal activity is the neurobiological root of cognition. Although the internal state that we call the mind is guided by the senses, it is also generated by the oscillations within the brain. Thus, in a certain sense, one could say that reality is not all out there, but is a kind of virtual reality.
Repair of pars defect in a patient accompanied with disc herniation by a modified Buck's. (2012)

Direct repair of spondylolysis with disc degeneration at cranial adjacent level combined with disc herniation at spondylolytic level may be debatable. We take it as an alternative to the established treatment.
Hybrid Acoustic-elastic Modeling Method Using Adaptive Grid Finite Difference Scheme in Marine Environment (2013)

Shear- and mode-converted waves provide rich information for further improving the image quality of complex geological structures and quantification of reservoir characterization. Multi-component seismic data acquisition has become more and more popular for surface seismic, Ocean Bottom Cable (OBC), and Vertical Seismic Profile (VSP) over the recent years. The staggered-grid finite-difference (FD) method with velocity-stress wave equation is often used for elastic wave simulation. Conventional elastic wave simulation uses fixed-grid discretization throughout the 3D volume. It requires a huge computing cost and encounters oversampling with high velocity. In order to make elastic modeling more cost effective in marine environment, we propose a new hybrid method to perform 3D elastic modeling. We implement the first-order acoustic wave equation used in water layer and the velocity-stress elastic wave equation with adaptive grid in solid sediment. The numerical result of the hybrid method matches very well with the conventional approach using fixed-grid implementation with full elastic wave equation. Test on the SEAM model also demonstrates that this method is capable for modeling surface seismic, OBC and VSP acquisition geometry with greatly improved efficiency and less used computing resource.
Setting up virtual security zones in a Linux cluster (2004)

When projects need to share the Linux cluster but shouldn't see each other's data, split your in-demand cluster into separate virtual ones.
Expression of c-erbB proto-oncogene family members in squamous cell carcinoma of the head and neck. (1998)

The exact role of oncogenes and proto-oncogenes in the development of squamous cell carcinoma of the head and neck (SCCHN) is still debatable. The expression of the c-erbB-2, c-erbB-3 and c-erbB-4 members of the epidermal growth factor receptor family was examined in 16 fresh frozen tissue specimens of SCCHN using avidin-biotin complex immunohistochemistry, with monoclonal and/or polyclonal antibodies directed against each. Eight fresh frozen tissue specimens of normal oral mucosa were included as controls. Of the SCCHN examined, mixed membrane/cytoplasmic staining (moderate to intense) of c-erbB-2 was found in 14/16 cases (88%). When present in the specimen, immunopositive staining of c-erbB-2 was seen in some of the oral surface epithelial cell layers (basal, intermediate and/or superficial) as well as the tumour islands. Weak cytoplasmic staining of c-erbB-3 and c-erbB-4 was found in 13/16 (81%) and 11/16 (69%) cases respectively. When present in the specimen, c-erbB-3 and cerbB-4 immunopositive staining was seen in some of the oral surface epithelial cell layers (basal, intermediate and/or superficial) as well as the tumour islands. For the positive carcinomas for c-erbB-2, c-erbB-3 and c-erbB-4, the epithelium located near the carcinomas showed weak mixed membrane/cytoplasmic staining of c-erbB-2 in 5/14 cases (36%), weak cytoplasmic staining of c-erbB-3 in 7/13 cases (54%) and of c-erbB-4 in 3/11 cases (27%). All the normal control oral mucosa showed the same pattern of staining for c-erbB-2, c-erbB-3 and c-erbB-4 found in the epithelium located near the carcinomas. Only expression of c-erbB-2 was found to correlate with the increase in the tumour stage, while co-expression of c-erbB-2, c-erbB-3 and c-erbB-4 was found to correlate with the patient survival time in 25% of the carcinomas examined. The present study shows that a) expression of c-erbB-2, but not c-erbB-3 and c-erbB-4 correlates with the increase of the tumour stage b) co-expression of c-erbB-2, c-erbB-3 and c-erbB4 correlates with decreased survival time in some of the cases of SCCHN, but not the majority c) co-expression of the c-erbB family in normal oral mucosa as well as in the carcinoma may question whether the increased tendency for development of the disease is due to co-expression of c-erbB proto-oncogenes in head and neck lesions.
Identification of a New<i>Arabidopsis</i>Disease Resistance Locus,<i>RPS4,</i>and Cloning of the Corresponding Avirulence Gene,<i>avrRps4,</i>from<i>Pseudomonas syringae</i>pv.<i>pisi</i> (1996)

A molecular genetic approach was used to study the interaction between Arabidopsis and an avirulence gene from Pseudomonas syringae pv. pisi. P. syringae pv. pisi strain 151 induces a hypersensitive response (HR) when inoculated on the Arabidopsis accession Po-1. A genomic cosmid library was constructed from DNA from P. syringae pv. pisi strain 151 and a cosmid was identified that causes the normally virulent P. syringae pv. tomato strain DC3000 to induce an HR on Po-1. The cosmid was subcloned and a 1.2-kb DNA fragment conferring avirulence activity was sequenced. The single significant open reading frame within the 1.2-kb fragment was designated avrRps4. An avrRps4-specific probe hybridizes to DNA from all P. syringae pv. pisi strains tested. P. syringae strains carrying avrRps4 induces an HR on specific accessions of both Arabidopsis and soybean. Arabidopsis accession Ws-0 is resistant to DC3000(avrRps4), whereas accession RLD is susceptible. Resistance segregates as a single dominant locus in a genetic cross between Ws-0 and RLD. This disease resistance locus, RPS4, was mapped to chromosome 5 between the molecular markers sAT2105 and KG-8.
Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABA<sub>A</sub>receptors as an opportunity for drug development? (2008)

Alcohol (ethanol, EtOH) has pleiotropic actions and induces a number of acute and long-term effects due to direct actions on alcohol targets, and effects of alcohol metabolites and metabolism. Many detrimental health consequences are due to EtOH metabolism and metabolites, in particular acetaldehyde, whose high reactivity leads to nonspecific chemical modifications of proteins and nucleic acids. Like acetaldehyde, alcohol has been widely considered a nonspecific drug, despite rather persuasive evidence implicating inhibitory GABA(A) receptors (GABA(A)Rs) in acute alcohol actions, for example, a GABA(A)R ligand, the imidazobenzodiazepine Ro15-4513 antagonizes many low-to-moderate dose alcohol actions in mammals. It was therefore rather surprising that abundant types of synaptic GABA(A)Rs are generally not responsive to relevant low concentrations of EtOH. In contrast, delta-subunit-containing GABA(A)Rs and extrasynaptic tonic GABA currents mediated by these receptors are sensitive to alcohol concentrations that are reached in blood and tissues during low-to-moderate alcohol consumption. We recently showed that low-dose alcohol enhancement on highly alcohol-sensitive GABA(A)R subtypes is antagonized by Ro15-4513 in an apparently competitive manner, providing a molecular explanation for behavioural Ro15-4513 alcohol antagonism. The identification of a Ro15-4513/EtOH binding site on unique GABA(A)R subtypes opens the possibility to characterize this alcohol site(s) and screen for compounds that modulate the function of EtOH/Ro15-4513-sensitive GABA(A)Rs. The utility of such drugs might range from novel alcohol antagonists that might be useful in the emergency room, to drugs for the treatment of alcoholism, as well as alcohol-mimetic drugs to harness acute positive effects of alcohol.
Review: <i>The Scientific American Book of Projects for the Amateur Scientist</i>, by C. L. Stong (1961)

Book Review| November 01 1961 Review The Scientific American Book of Projects for the Amateur ScientistC. L. Stong P. K. P. K. Search for other works by this author on: This Site PubMed Google Scholar The American Biology Teacher (1961) 23 (7): 455–456. https://doi.org/10.2307/4439699 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation P. K.; Review. The American Biology Teacher 1 November 1961; 23 (7): 455–456. doi: https://doi.org/10.2307/4439699 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentThe American Biology Teacher Search This content is only available via PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Effects of Pravastatin on Murine Chronic Graft-Versus-Host Disease (2010)

This study suggests that the CGVHD-protecting effect of PST involves the down-regulation of chemokines and the reduction of collagen synthesis.