gebhart/patrepeval huggingface dataset:
Feature Extraction Algorithm Based on Locality and Globality and its Application in Face Recognition (2009)

A feature extraction algorithm based on locality and globality was proposed,which on one hand takes the locality of the data into consideration,on the other hand takes the globality of data into account.Consequently,the data after dimension reduction not only preserves the locality relationship,but also reconstructs and represents the original data perfectly.PCA(Principal Component Analysis) can represent the data nicely and LPP(Locality Preserving Projection) can preserve the locality relationship,so the algorithm just hybrid the two of them.But LPP does not utilize the classification information,so first LPP-based algorithm is improved,a supervised version is given,which results in that the algorithm is more suitable for classification task.Experiments in face recognition validate the correctness and effectiveness of the proposed algorithm.
Reactive ion etch of silicon nitride spacer with high selectivity to oxide (2002)

A highly uniform and selective nitride spacer etch process for use in advanced sub-0.35 /spl mu/m devices has been developed in the Dielectric Etch M/spl times/P+ MERIE chamber. One application involves etching the nitride film down to the gate oxide with minimal oxide loss. The nitride spacer process is also used to etch the nitride and oxide while stopping on the silicon. This process was developed for both 150 mm and 200 mm M/spl times/P+ chambers. Obtaining a good uniformity and high selectivities while maintaining a vertical profile is essential to a production worthy process. A CHF/sub 3//Ar based main etch process provides a controllable nitride etch rate (800-1700 /spl Aring//min) with good uniformity (/spl sim/4%, max-min/2*ave) while providing a proper profile and maintaining the spacer width. This main etch process gives a high selectivity to silicon. A second, CH/sub 3/F/O/sub 2/ based process step is used for overetch past the endpoint to stop on oxide with minimal oxide loss (<50 /spl Aring/).
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma (1997)

Mutations of the p53 gene are associated with a poor prognosis in patients with aggressive B-cell lymphoma.
Polymer degradation & stabilisation (1985)

The study of polymer degradation and stabilisation is of considerable practical importance as the industrial uses of polymeric materials continue to expand. In this book, the authors lucidly relate technological phenomena to the chemistry and physics of degradation and stabilisation processes. Degradation embraces a variety of technologically important phenomena ranging from relatively low temperature processes such as 'weathering' of plastics, 'fatigue' of rubbers through the processing of polymers in shearing mixers to very high temperature processes such as flammability and ablation. All these technological phenomena have in common certain basic chemical reactions. Thus 'weathering' has its roots in photo-oxidation, 'fatigue' and melt-degradation in mechano-oxidation and flammability, and ablation in ablation in pyrolysis and vapour phase oxidation.
Transcription factor SIII: a novel component of the RNA polymerase II elongation complex. (1993)

A growing body of evidence suggests that the elongation stage of eukaryotic messenger RNA synthesis is a major site for the regulation of gene expression. In the process of investigating the mechanism of promoter-specific transcription by RNA polymerase II, we recently identified and purified a novel transcription factor that controls RNA chain elongation. This factor, which we have designated SIII, has a native molecular mass of 140 kDa and is composed of three polypeptides of 110, 18, and 15 kDa. Results of renaturation experiments indicate that all three polypeptides are required to reconstitute SIII transcriptional activity. A variety of evidence from mechanistic studies reveals that SIII dramatically stimulates the rate of RNA chain elongation by RNA polymerase II, most likely through a direct interaction with transcribing polymerase. Here we describe the properties of SIII as well as its role in regulating the activity of the RNA polymerase II elongation complex.
SEISMIC IN ST. LOUIS (1997)

Following collapse of sections of the double-deck I-880 Cypress Viaduct in the 1989 Loma Prieta earthquake, the Missouri Department of Transportation initiated a seismic evaluation and retrofit of the of the U.S. 40/I-64 bridge complex in St. Louis. The link, which carries more than 130,000 vehicles per day between Missouri and Illinois, was designed in the mid-1960s and includes more than 15,700 ft of side-by-side and double-deck roadway. The seismic evaluation, performed by Sverdrup Civil, Inc., identified a number of deficiencies needing serious attention. The retrofit will include competitive procurement of a seismic isolation system, hinge bearing replacement, shock transmitters, cross-frame modifications, column jackets and foundation mechanics.
Plasticity of Cadherin–Catenin Expression in the Melanocyte Lineage (2000)

Cadherins are calcium-dependent cell adhesion receptors with strong morphoregulatory functions. To mediate functional adhesion, cadherins must interact with actin cytoskeleton. Catenins are cytoplasmic proteins that mediate the interactions between cadherins and the cytoskeleton. In addition to their role in cell-cell adhesion, catenins also participate in signaling pathways that regulate cell growth and differentiation. Cadherins and catenins appear to be involved in melanocyte development and transformation. Here, we investigated the function of cadherin-catenin complexes in the normal development and transformation of melanocytes by studying the patterns of expression of the cell-cell adhesion molecules, E-, N- and P-cadherin, and the expression of their cytoplasmic partners, alpha-, beta- and gamma-catenin during murine development. Similar analyses were performed in vitro using murine melanoblast, melanocyte, and melanoma cell lines in the presence and absence of keratinocytes, the cells with which melanocytes interact in vivo. Overall, the results suggest that the expression of cadherins and catenins is very plastic and depends on their environment as well as the transformation status of the cells. This plasticity is important in fundamental cellular mechanisms associated with normal and pathological ontogenesis, as well as with tumorigenesis.
Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results (2020)

In this single-center, retrospective cohort study, likely deficient vitamin D status was associated with increased COVID-19 risk, a finding that suggests that randomized trials may be needed to determine whether vitamin D affects COVID-19 risk.
Robot learning to walk: An architectural problem for intelligent controllers (2002)

The authors analyze the design premises of a new control architecture based on the principle of nested hierarchical control which has the feature of learning from the already programmed skills of a teleoperated system. Different architectural principles are explored and compared. It is shown how high level languages can be built from low level knowledge by using cooperation of the already existing skills, new expert knowledge (teaching new heuristics), and self-experience (example based) learning.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Interfacial tensions of three fluid phases in equilibrium (1975)

It is suggested that it may be a general thermodynamic law that when three mutually saturated fluid phases are in equilibrium, the three interfacial tensions σ satisfy the triangle inequality σmax &lt; σmed + σmin, where σmax is the largest of the three, σmed the median, and σmin the smallest. An argument for the inequality is given, and systems in which to test it experimentally are suggested. The quantitative law by which the interfacial tensions vanish as the three fluid phases become identical at a tricritical point is derived by an adaptation of an earlier argument on the vanishing of the interfacial tension on approach to the tricritical point in phase−separated 3He−4He mixtures.
Performance of handoff algorithm based on distance and RSSI measurements (2002)

The performance of a proposed handoff algorithm based on both the distance of a mobile station to neighboring base stations and the relative signal strength measurements is evaluated. The algorithm performs handoff when the measured distance from the serving base station exceeds that from the candidate base station by a given threshold and if the measured signal strength of the adjacent base station exceeds that of the serving base station by a given hysteresis level. The average handoff delay and average number of handoffs are used as criteria for performance. Numerical results are presented to demonstrate the feasibility of the distance-based handoff algorithm, including results for an additional criterion based on relative signal strength. The proposed algorithm is compared with an algorithm based on absolute and relative signal strength measurements and with a solely distance-based algorithm. It is found that the proposed handoff algorithm performs well in a log-normal fading environment when the distance estimate error is modeled by wide-sense stationary additive white Gaussian noise.
Volatile components in the steam distillate of rice bran: Identification of neutral and basic compounds. (1978)

Neutral and basic fractions obtained from the volatile concentrate of rice bran were analyzed by glass capillary gas chromatography. N- or S-containing compounds in the basic fraction were detected with a flame thermionic detector (FTD) or a flame photometric detector (FPD). A total of 146 compounds (alkanes, aromatic hydrocarbons, alcohols, aldehydes, ketones, esters, lactones, furans, pyridines, pyrazines, quinolines, thiazoles, thiophenes etc.), in addition to the 7 phenols and 17 acids reported previously, were newly identified in the neutral and basic fractions from the volatile concentrate of rice bran. 2-Acetylthiazole and benzothiazole in the concentrate were considered to be the key compounds of the rice bran odor, and other compounds, for example lactones, were also estimated to be necessary for reproduction of the odor.
Cellular architecture and key technologies for 5G wireless communication networks (2014)

The fourth generation wireless communication systems have been deployed or are soon to be deployed in many countries. However, with an explosion of wireless mobile devices and services, there are still some challenges that cannot be accommodated even by 4G, such as the spectrum crisis and high energy consumption. Wireless system designers have been facing the continuously increasing demand for high data rates and mobility required by new wireless applications and therefore have started research on fifth generation wireless systems that are expected to be deployed beyond 2020. In this article, we propose a potential cellular architecture that separates indoor and outdoor scenarios, and discuss various promising technologies for 5G wireless communication systems, such as massive MIMO, energy-efficient communications, cognitive radio networks, and visible light communications. Future challenges facing these potential technologies are also discussed.
Dynamic TDMA slot reservation protocol for cognitive radio ad hoc networks (2010)

In this paper, we propose a dynamic TDMA slot reservation (DTSR) protocol for cognitive radio ad hoc networks. Quality of Service (QoS) guarantee plays a critically important role in such networks. We consider the problem of providing QoS guarantee to users as well as to maintain the most efficient use of scarce bandwidth resources. A dynamic frame length expansion and shrinking scheme that controls the excessive increase of unassigned slots has been proposed. This method efficiently utilizes the channel bandwidth by assigning unused slots to new neighboring nodes and increasing the frame length when the number of slots in the frame is insufficient to support the neighboring nodes. It also shrinks the frame length in an effective way. Our proposed scheme, which provides both QoS guarantee and efficient resource utilization, be employed to optimize the channel spatial reuse and maximize the system throughput. Extensive simulation results show that the proposed mechanism achieves significant performance improvement in multichannel cognitive radio ad hoc networks.
Catecholamines increase nerve growth factor mRNA content in both mouse astroglial cells and fibroblast cells (1989)

Previous studies have shown that catecholamines increase the nerve growth factor (NGF) content in medium conditioned by mouse L-M fibroblast cells and mouse astroglial cells. In this study, the NGF mRNA levels in these cells were measured by Northern blot analysis. In astroglial cells treated with epinephrine (EN), the cellular NGF mRNA level increased prior to accumulation of NGF in the culture medium. 3-Hydroxytyramine (DA) and norepinephrine (NE) also increased the cellular NGF mRNA content. An increased level of NGF mRNA elicited by EN was also observed in mouse L-M cells. These results indicate that catecholamines enhance NGF synthesis of L-M fibroblast cells and astroglial cells by increasing the cellular content of NGF mRNA. The present results also indicate that the effects of catecholamines are not mediated by adrenergic receptors.
Paracetamol intoxication and N-acetyl-cysteine treatment. (1996)

N-acetylcysteine is a good and reasonable specific antidotum in case of paracetamol intoxication. It is very active when administered within eight hours after intoxication. It can be used as well as in intravenous as peroral administration. There are few side effects.
Implanted programmable insulin pumps: One hundred fifty-three patient years of surgical experience (1997)

Long-term use of IIPs results in significant improvements in clinical parameters and quality of life for individuals with insulin-dependent diabetes mellitus. Relatively frequent operations are required for maintaining pump function, which are done with a local anesthetic with minimal morbidity.
The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2 (2011)

Mutations of the Interleukin-1-receptor accessory protein like 1 (IL1RAPL1) gene are associated with cognitive impairment ranging from non-syndromic X-linked mental retardation to autism. IL1RAPL1 belongs to a novel family of IL1/Toll receptors, which is localized at excitatory synapses and interacts with PSD-95. We previously showed that IL1RAPL1 regulates the synaptic localization of PSD-95 by controlling c-Jun N-terminal kinase activity and PSD-95 phosphorylation. Here, we show that the IgG-like extracellular domains of IL1RAPL1 induce excitatory pre-synapse formation by interacting with protein tyrosine phosphatase delta (PTPδ). We also found that IL1RAPL1 TIR domains interact with RhoGAP2, which is localized at the excitatory post-synaptic density. More interestingly, the IL1RAPL1/PTPδ complex recruits RhoGAP2 at excitatory synapses to induce dendritic spine formation. We also found that the IL1RAPL1 paralog, IL1RAPL2, interacts with PTPδ and induces excitatory synapse and dendritic spine formation. The interaction of the IL1RAPL1 family of proteins with PTPδ and RhoGAP2 reveals a pathophysiological mechanism of cognitive impairment associated with a novel type of trans-synaptic signaling that regulates excitatory synapse and dendritic spine formation.
Glycomics for Drug Discovery: Metabolic Perturbation in Androgen‐Independent Prostate Cancer Cells Induced by Unnatural Hexosamine Mimics (2012)

Inhibited: N-acetylglucosamine (GlcNAc) derivatives with a fluorine atom at the C4 position (2-4) were synthesized, and their ability to inhibit cancer-cell growth was investigated. The administration of these 4F-GlcNAc derivatives to cells led to the unnatural sugar nucleotide 1. Furthermore, N-glycan profiles of cells were determined by using a glycoblotting-based enrichment analysis, which is suitable for high-throughput screenings for drug discovery.
Endocannabinoids in the regulation of appetite and body weight (2005)

The discovery of cannabinoid receptors, together with the development of selective cannabinoid receptor antagonists, has encouraged a resurgence of cannabinoid pharmacology. With the identification of endogenous agonists, such as anandamide, scientists have sought to uncover the biological role of endocannabinoid systems; initially guided by the long-established actions of cannabis and exogenous cannabinoids such as delta9-tetrahydrocannabinol (THC). In particular, considerable research has examined endocannabinoid involvement in appetite, eating behaviour and body weight regulation. It is now confirmed that endocannabinoids, acting at brain CB1 cannabinoid receptors, stimulate appetite and ingestive behaviours, partly through interactions with more established orexigenic and anorexigenic signals. Key structures such as the nucleus accumbens and hypothalamic nuclei are sensitive sites for the hyperphagic actions of these substances, and endocannabinoid activity in these regions varies in relation to nutritional status and feeding expression. Behavioural studies indicate that endocannabinoids increase eating motivation by enhancing the incentive salience and hedonic evaluation of ingesta. Moreover, there is strong evidence of an endocannabinoid role in energy metabolism and fuel storage. Recent developments point to potential clinical benefits of cannabinoid receptor antagonists in the management of obesity, and of agonists in the treatment of other disorders of eating and body weight regulation.
The Effects of a 5-Lipoxygenase Inhibitor on Asthma Induced by Cold, Dry Air (1990)

Selective inhibition of 5-lipoxygenase by A-64077 is associated with a significant amelioration of the asthmatic response to cold, dry air, suggesting that 5-lipoxygenase products are involved in this response. This approach may be useful in the treatment of asthma.
High Speed <sup>1</sup>H Spectroscopic Imaging in Human Brain by Echo Planar Spatial‐Spectral Encoding (1995)

We introduce a fast and robust spatial-spectral encoding method, which enables acquisition of high resolution short echo time (13 ms) proton spectroscopic images from human brain with acquisition times as short as 64 s when using surface coils. The encoding scheme, which was implemented on a clinical 1.5 Tesla whole body scanner, is a modification of an echo-planar spectroscopic imaging method originally proposed by Mansfield Magn. Reson. Med. 1, 370-386 (1984), and utilizes a series of read-out gradients to simultaneously encode spatial and spectral information. Superficial lipid signals are suppressed by a novel double outer volume suppression along the contours of the brain. The spectral resolution and the signal-to-noise per unit time and unit volume from resonances such as N-acetyl aspartate, choline, creatine, and inositol are comparable with those obtained with conventional methods. The short encoding time of this technique enhances the flexibility of in vivo spectroscopic imaging by reducing motion artifacts and allowing acquisition of multiple data sets with different parameter settings.
Liposomal (MLV) Polymyxin B: Physicochemical Characterization and Effect of Surface Charge on Drug Association (1993)

Neutral and charged large vortexed multilamellar hydrogenated egg phosphatidylcholine liposomes containing the polycationic antibiotic polymyxin B (PXB) were characterized with respect to lipid-drug interactions (differential scanning calorimetry), surface charge (zeta potential analysis), size (photon correlation spectroscopy) and morphology (transmission electron microscopy). These physicochemical results will be used to develop a liposomal drug delivery system for PXB that may be useful in the clinical treatment of lung infection in cystic fibrosis patients. The liposomal morphology and membrane integrity of all the preparations were unaffected by associated antibiotic. Drug encapsulation increased in the order neutral = positive < negative, the negatively charged liposomes increasing drug association 2-fold. The phase transition temperature of neutral and positive liposomes was not significantly affected by PXB. Drug-loaded negative liposomes showed a decreased phase transition possibly due to attractive electrostatic interactions between drug and lipid that tended to increase drug penetration and destabilize the liposome bilayer. Drug loading did not affect liposome size. However, both empty and loaded negative liposomes were significantly smaller (approx. 1 micron) than neutral and positive (approx. 2.5 microns) liposomes. Increased encapsulation with negative liposomes is therefore due not to an increase in the entrapped volume but to electrostatic interactions.
The effects of β-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis (2009)

The purpose of this study was to evaluate the effect of β-(1,3/1,6)-D: -glucan isolated from Pleurotus ostreatus (β-glucan-PO) on prophylactic treatment of adjuvant arthritis (AA) with methotrexate (MTX) in rats. Groups of rats with AA were treated with methotrexate (1 mg/kg/week), β-glucan-PO (1 mg/kg every second day) or their combination for the period of 28 days from adjuvant application. Body mass, hind paw swelling, arthrogram scores and a level of serum albumin were measured as markers of inflammation and arthritis. Treatment with low dose of MTX significantly inhibited the markers of both inflammation and arthritis. MTX and its combination with β-glucan-PO significantly increased body mass of arthritic rats. β-glucan-PO administered alone significantly decreased both the hind paw swelling and arthritic score. In combination with MTX, β-glucan-PO markedly potentiated the beneficial effects of MTX, which resulted in a more significant reduction of hind paw swelling and arthritic scores. The concentration of albumin in the serum of arthritic controls was significantly lower than in healthy controls. Both MTX alone and the combination treatment with MTX + β-glucan-PO significantly inhibited the decrease in serum albumin. β-Glucan-PO increased the treatment efficacy of basal treatment of AA with MTX.
Calorimeter for absolute laser c.w. radiation-power measurements (1967)

The construction and performance of a calorimeter for absolute measurements of c.w. laser power are described. The device does not require any calibration against a standard power source. It contains a copper-wire-wound bolometer and is designed for the range of 0.2–25 mW with accuracy of within 3%.
Probiotic Bacterium Prevents Cytokine-induced Apoptosis in Intestinal Epithelial Cells (2002)

Probiotic bacteria are microorganisms that benefit the host by preventing or ameliorating disease. However, little information is known regarding the scientific rationale for using probiotics as alternative medicine. The purpose of this paper is to investigate the mechanisms of probiotic beneficial effects on intestinal cell homeostasis. We now report that one such probiotic, Lactobacillus rhamnosus GG (LGG), prevents cytokine-induced apoptosis in two different intestinal epithelial cell models. Culture of LGG with either mouse or human colon cells activates the anti-apoptotic Akt/protein kinase B. This model probiotic also inhibits activation of the pro-apoptotic p38/mitogen-activated protein kinase by tumor necrosis factor, interleukin-1alpha, or gamma-interferon. Furthermore, products recovered from LGG culture broth supernatant show concentration-dependent activation of Akt and inhibition of cytokine-induced apoptosis. These observations suggest a novel mechanism of communication between probiotic microorganisms and epithelia that increases survival of intestinal cells normally found in an environment of pro-apoptotic cytokines.