gebhart/patrepeval huggingface dataset:
Interactions between <i>N</i>–acetylcysteine and sodium selenite in modulating the clastogenicity of urethane and 2–acetylaminofluorene in mice (2003)

Combined treatment with different agents represents a promising approach in cancer chemoprevention. Therefore, it is useful to assess in preclinical models the efficacy of combinations that are selected by taking into account mechanistic considerations. We designed 2 studies evaluating the interaction between N-acetylcysteine (NAC) and sodium selenite (Se), both given with the drinking water to Balb/c mice, in modulating clastogenic effects in bone marrow polychromatic erythrocytes. In a first study, a single i.p. injection of urethane considerably enhanced the frequency of micronucleated cells. While NAC produced a significant inhibition, Se further enhanced urethane clastogenicity. When given in combination at the same doses, NAC prevented the adverse effect of Se. In a second study, a single i.p. injection of 2-acetylaminofluorene enhanced the frequency of micronucleated cells. Se did not reduce this effect to a significant extent, while NAC produced a dose-dependent inhibition. When tested at the lower dose in combination with Se, the protective effect of NAC was unchanged. Especially in association with Se, NAC also prevented the toxicity of 2-acetylaminofluorene by normalizing the ratio of polychromatic to normochromatic erythrocytes. In conclusion, NAC attenuated the clastogenicity of both urethane and 2-acetylaminofluorene and the toxicity of this aromatic amine. In addition, NAC prevented the clastogenic and toxic effects resulting from the interaction of Se with urethane. Together with the findings of previous studies, it appears that, besides its intrinsic protective properties in carcinogenesis, NAC is capable of attenuating the adverse effects of several cytotoxic drugs and chemopreventive agents.
Use of Apodized Metal Gratings in Fabricating Low Cost Quartz RAC Filters (1980)

This paper describes a straightforward design technique for making low cost RAC filters on quartz substrates. This approach utilizes a simple apodization scheme to control the response of metal reflection gratings that are made with conventional photolithographic processes. A set of quartz RAC lines having a 20% operating bandwidth at 51.2 MHz, and a dispersive time delay of 50 psec. have shown that this technique is capable of producing modest time-bandwidth product devices with excellent performance characteristics. This paper also presents the results of series of experiments that were conducted to determine the 90° reflection characteristics of shorted metal gratings on various rotated y-cut quartz substrates. Data used to determine the single striple reflection coefficient of aluminum stripes on y-cut substrates with rotation angles of 32' to 42.75O is presented together with measurements of the temperature coefficients of delay for these materials. A new technique for determining the stripe angle required to obtain 90' reflections on a Given substrate material is described and its use in measuring the desired stripe angle for the above rotated y-cut substrates is summarized.
Real time 3D avatar for interactive mixed reality (2004)

This paper presents real-time reconstruction of dynamic 3D avatar for interactive mixed reality. In computer graphics, one of the main goals is the combination of virtual scenes with real-world scenes. However, the views of the real world objects are often restricted to views from the cameras. True navigation through such mixed reality scenes becomes impossible unless the components from real objects can be rendered from arbitrary viewpoints. Additionally, adding a real-world object to a virtual scene requires some depth information as well, in order to handle interaction. The proposed algorithm introduces an approach to generate 3D video avatars and to augment the avatars naturally into 3D virtual environment using the calibrated camera parameters and silhouette information. As a result, we can create photo-realistic live avatars from natural scenes and the resulting 3D live avatar can guide and interact participants in VR space.
Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double‐blind placebo‐controlled trial (2004)

Treatment with LGG may alleviate AEDS symptoms in IgE-sensitized infants but not in non-IgE-sensitized infants.
Oceansense (2010)

In this project, we explore the possibility of deploying networked sensors on the Ocean's surface, to monitor depth and temperature, as well as other valuable environmental parameters. Sea depth monitoring is a critical task to ensure the safe operation of harbors. Traditional schemes largely rely on labor-intensive work and expensive hardware. We present a new solution for measuring the sea depth with Restricted Floating Sensors. To address the problem of node localization on the changeable sea environment, we propose Perpendicular Intersection (PI), a novel mobile-assisted localization scheme. In the OceanSense project, we propose the concept of passive diagnosis as well as the PAD approach which is both lightweight and adaptive to network dynamics. The OceanSense system has been working for over 16 months and provides large amounts of valuable data about the sea.
PRIDE: A Private and Decentralized Usage-Based Insurance Using Blockchain (2018)

Usage-based Insurance (UBI) for vehicles determines the insurance premiums according to actual usage and driving pattern. It can significantly reduce insurance costs for safe drivers, however, UBI schemes require detailed driving data to determine the insurance premiums, which may lead to serious privacy breach for drivers. Moreover, most existing UBI schemes require a centralized insurance company as the intermediary to manage insurances. Such a centralized solution incurs too much monetary costs as well as time cost. In this paper, we propose PRIDE, a privacy-preserving and decentralized UBI scheme using the blockchain to record encrypted driving data, and the smart contract running on the blockchain to calculate insurance premiums. Different from existing UBI schemes, PRIDE achieves security and privacy without relying on any centralized party or any trusted/tamper-proof hardware. We have analyzed security of PRIDE and evaluated its performance. The results show that PRIDE is very efficient in processing UBI insurances - each insurance request can be processed in about 898ms.
Biomineralization of iron: Moessbauer spectroscopy and electron microscopy of ferritin cores from the chiton Acanthopleura hirtosa and the limpet Patella laticostata (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiomineralization of iron: Moessbauer spectroscopy and electron microscopy of ferritin cores from the chiton Acanthopleura hirtosa and the limpet Patella laticostataT. G. St. Pierre, K. S. Kim, J. Webb, S. Mann, and D. P. E. DicksonCite this: Inorg. Chem. 1990, 29, 10, 1870–1874Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/ic00335a022https://doi.org/10.1021/ic00335a022research-articleACS PublicationsRequest reuse permissionsArticle Views206Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Coordination Tendency of Some Biologically Important Zwitterionic Buffers toward Metal Ion Nucleotide Complexes at Different Temperatures (2012)

The formation of binary and ternary complexes of Cu(II), Ni(II), Co(II), Mn(II), Zn(II), Ca(II), Mg(II), and Pd(II) with 4-morpholinoethane sulfonic acid (MES), 2-(cyclohexylamino)ethane sulfonic acid (CHES), and 3-[(N-tris)-(hydroxymethyl)methyl (amino)]-2-hydroxypropanesulfonic acid (TAPSO) as zwitterionic buffers and guanosine 5′-monophosphate (5′-GMP), inosine 5′-monophosphate (5′-IMP), and uridine 5′-monophosphate (5′-UMP) has been studied potentiometrically in the temperature range (288.15 to 318.15) K and at ionic strength I = 0.1 mol·dm–3 (KNO3). Initial estimates of the formation constants of the resulting species and the dissociation constants of the studied ligands have been refined with the SUPERQUAD computer program. The experimental conditions were selected such that self-association of the nucleotides and their complexes was negligibly small; that is, the monomeric and protonated complexes were studied.
Handbook Of Fatigue Testing (1974)

Description In 1949 Committee E-9 on Fatigue published ASTM STP 91, Manual of Fatigue Testing. The project leading to STP 91 involved the specific writing of eight members of E09 and the discussions and criticisms of members of the main committee over a period of three years. STP 91 was a modest effort and succeeded in presenting what was then considered to be the current practice and views of E09 members.
Spontaneous resolution of a large chronic subdural hematoma: a case report and review of the literature. (2009)

Spontaneous resolution of a chronic subdural hematoma has been reported rarely in the literature. We present herein the case of a 35-year-old patient with spontaneous resolution of a large chronic subdural hematoma, the volume of which was measured as approximately 76.5 ml on magnetic resonance imaging. No pathology was determined on neurological examination. Neither cerebral angiography nor EEG showed any abnormality. We discuss the possible relation between mechanisms of physio-pathogenesis and spontaneous resolution of chronic subdural hematomas, and also present the patient characteristics together with the other literature data.
Studies on Metal Chelates of 8-Hydroxy-5-quinolyl Ketone Oxime, <i>O</i>-Carbamoyl and <i>O</i>-Thiocarbamoyl Derivatives as Bactericides (1988)

Abstract The reaction of 5-acetyl-8-quinolinol (1) and corresponding chalcone derivatives 2a–f with hydroxylamine hydrochloride in boiling pyridine gave the corresponding oximes 3 and 4a–f respectively in almost quantitative yields. Further interaction of 3 and 4a–e with phenyl isocyanate and/or thiocyanate the corresponding carbamate and/or thiocarbamate (5a,b) and (6a–e, 7a–e) were achieved. Metal chelates of 1, 3, and 4e,f with bivalent metal cations like Fe(II), Cu(II), and Zn(II) have been synthesized and characterized by elemental and IR-spectral analysis. The synthesized compounds were biologically screened to study the structure activity relationship, (SAR) and the effect of complexation and type of metal cation on the potency of the more biologically active compounds.
Ruthenium(II) Bipyridyl Complexes as Photolabile Caging Groups for Amines (2006)

The synthesis and characterization of a series of ruthenium bis(bipyridine) complexes where the inorganic moiety acts as a photolabile protecting group is described. Complexes of the type [Ru(bpy)2L2]+ where bpy = 2,2'-bipyridine and L = butylamine, gamma-aminobutyric acid, tyramine, tryptamine, and serotonin were studied by nuclear magnetic resonance, cyclic voltammetry, and electronic absorption spectroscopy. In all cases, ligands are coordinated by the amine group. The complexes are stable in water for several days and deliver one molecule of ligand upon irradiation with visible light (450 nm). These properties make them suitable for their use as biological caged compounds.
Development of a Ceramic Micro Heat Exchanger – Design, Construction, and Testing (2005)

Abstract This article presents the development of a ceramic micro heat exchanger. Starting from its geometrical design, results obtained from a simplified simulation of the heat exchanger efficiency will be given. The alumina microcomponents were manufactured by a rapid prototyping process chain. Here, stereolithography was combined with a low‐pressure injection molding process for the rapid and precise manufacturing of ceramic components down to the micrometer range. A micro heat exchanger, joined from sintered components using a glass solder, was applied as a prototype and checked for its performance at a system pressure of 8 bar.
Selectivity, local rank, three‐way data analysis and ambiguity in multivariate curve resolution (1995)

Abstract A new multivariate curve resolution method is presented and tested with data of various levels of complexity. Rotational and intensity ambiguities and the effect of selectivity on resolution are the focus. Analysis of simulated data provides the general guidelines concerning the conditions for uniqueness of a solution for a given problem. Multivariate curve resolution is extended to the analysis of three‐way data matrices. The particular case of three‐way data where only one of the orders is common between slices is studied in some detail.
Performance Metrics of a 5 nm, Planar, Top Gate, Carbon Nanotube on Insulator (COI) Transistor (2007)

The performance of a planar, 5 nm top gate, carbon nanotube on insulator (COI) field-effect transistor (COIFET) with source/drain underlaps is analyzed. The performance metrics of switching delay time and cutoff frequency are calculated. A 2 nm thick, relatively low-K, SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> gate dielectric combined with a source/drain underlap geometry and insulating substrate minimizes the parasitic gate to source C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">GS</sub> and gate to drain C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">GD</sub> capacitances and results in a 23 fs switching delay time. The simplicity of the device design is required to satisfy the constraints of a self-assembly process. The device analyzed is also a scaled version of recently demonstrated CNTFETs on sapphire
Orientation classification by a winner-take-all network with oxide RRAM based synaptic devices (2014)

An emerging application for the oxide based resistive random access memory (RRAM) technology is to serve as the synaptic device for the hardware implementation of neuromorphic computing. The gradual resistance modulation capability in RRAM is proposed for emulating analog synapses, and the stochastic switching behavior in RRAM is proposed for emulating binary synapses. In order to evaluate the effectiveness of analog synapses and binary synapses in realizing the competitive learning algorithm, a simulation of winner-take-all network is performed based on the parameters extracted from the experiments. The simulation suggests that the orientation classification can be effectively realized using both analog synapses and binary synapses.
Formation of 2-Hydroxydeoxyadenosine Triphosphate, an Oxidatively Damaged Nucleotide, and Its Incorporation by DNA Polymerases (1995)

We found that hydroxylation occurs at the C-2 position of adenine by oxygen radical treatment (Fe2+-EDTA) of dA, dATP, and single- and double-stranded DNA. This oxidatively damaged base, 2-hydroxyadenine, was produced 3-6-fold and 40-fold less than 8-hydroxyguanine when monomers and polynucleotides, respectively, were treated. To determine whether the damaged nucleotide, 2-hydroxydeoxyadenosine triphosphate (2-OH-dATP), is incorporated into a growing DNA, and to reveal the kinds of nucleotides opposite which 2-OH-dATP is incorporated, calf thymus DNA polymerase α and the Klenow fragment of Escherichia coli DNA polymerase I were used in in vitro DNA synthesis in the presence of 2-OH-dATP. DNA polymerase α incorporated the nucleotide opposite T and C in the DNA template. On the other hand, in an experiment using the Klenow fragment, incorporation of 2-OH-dATP was observed only opposite T. Steady-state kinetic studies indicated that incorporation of 2-OH-dATP by DNA polymerase α opposite T was favored over that opposite C by a factor of only 4.5. These results indicate that 2-OH-dATP, an oxidatively damaged nucleotide, is a substrate for DNA polymerases and is incorporated incorrectly by the replicative DNA polymerase. We found that hydroxylation occurs at the C-2 position of adenine by oxygen radical treatment (Fe2+-EDTA) of dA, dATP, and single- and double-stranded DNA. This oxidatively damaged base, 2-hydroxyadenine, was produced 3-6-fold and 40-fold less than 8-hydroxyguanine when monomers and polynucleotides, respectively, were treated. To determine whether the damaged nucleotide, 2-hydroxydeoxyadenosine triphosphate (2-OH-dATP), is incorporated into a growing DNA, and to reveal the kinds of nucleotides opposite which 2-OH-dATP is incorporated, calf thymus DNA polymerase α and the Klenow fragment of Escherichia coli DNA polymerase I were used in in vitro DNA synthesis in the presence of 2-OH-dATP. DNA polymerase α incorporated the nucleotide opposite T and C in the DNA template. On the other hand, in an experiment using the Klenow fragment, incorporation of 2-OH-dATP was observed only opposite T. Steady-state kinetic studies indicated that incorporation of 2-OH-dATP by DNA polymerase α opposite T was favored over that opposite C by a factor of only 4.5. These results indicate that 2-OH-dATP, an oxidatively damaged nucleotide, is a substrate for DNA polymerases and is incorporated incorrectly by the replicative DNA polymerase.
The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells. (1998)

The murine Fhit locus maps near the centromere nu proximal Ptprg locus on mouse chromosome 14. The cDNA sequence and structure are similar to those of the human gene, with exons 5-9 encoding the protein. The predominant mRNA in the tissues and cell lines tested was an alternatively spliced form missing exon 3. Most murine cell lines tested, including lines established from normal mouse embryos and tumors, expressed very low or undetectable levels of Fhit mRNA. Most normal mouse tissues expressed wild-type Fhit mRNA, whereas approximately 40% of murine lung carcinomas expressed wild-type and aberrant Fhit RT-PCR products that lacked various exons. Several tumorigenic mouse cell lines exhibited homozygous deletions of Fhit exons. We conclude that the murine Fhit gene, like its human counterpart, is a target of alterations involved in murine carcinogenesis.
De novo glucan synthesis by mutans streptococcal glucosyltransferases present in pellicle promotes firm binding of<i>Streptococcus gordonii</i>to tooth surfaces (1992)

Adherence of 3H-labelled cells of Streptococcus gordonii and Streptococcus milleri to artificial pellicles prepared from saliva supplemented with glucosyltransferases from mutans streptococci was examined using a new assay for sucrose-dependent cell-to-pellicle attachment. Results indicate that S. gordonii, but not S. milleri, could attach tightly to hydroxylapatite surfaces through de novo glucan synthesis by mutans streptococcal glucosyltransferases present in the experimental salivary pellicles.
Adaptive MIMO Successive Interference Cancellation Decision Feedback Equalization RLS algorithm for V-BLAST (2007)

We present a new receiver structure able to deliver high data rates in a multi-input-multi-output (MIMO) frequency selective wireless environment. The new algorithm is obtained by canceling interference from the received symbols successively with the decision feed-forward equalizer (DFE) solution as a well known expression encountered in fast recursive least squares (RLS) adaptive algorithms, and the decision feedback equalizer as a convolution of the decision feed-forward equalizer with the channel. The proposed method is more structured and more stable in finite precision than known algorithms in the literature. The convergence and performance of these algorithms is confirmed through simulation results.
Potential Role of Pyrophosphate:Fructose 6-Phosphate Phosphotransferase in Carbohydrate Metabolism of Cold Stored Tubers of <i>Solanum tuberosum</i> cv Bintje (1991)

To gain a better understanding of the mechanism of cold induced sweetening, sugar accumulation in potato, Solanum tuberosum cv Bintje, was compared to the maximum activity of inorganic pyrophosphate (PPi):fructose 6-phosphate 1-phosphotransferase (EC 2.7.1.90) and the concentration of two regulatory metabolites. Mature tubers accumulated reducing sugars and sucrose at an almost linear rate of 13.4 and 5.2 micromole per day per gram dry weight at 2 degrees C and 4.5 and 1.3 micromole per day per gram dry weight, respectively, at 4 degrees C. During storage at 8 degrees C sugar accumulation was nil. Sugar accumulation was preceded by a lag phase of about 4 days. The accumulation of reducing sugars persisted for at least 4 weeks, whereas sucrose accumulation declined after 2 weeks of storage. The ratio of glucose:fructose changed concomitantly with sugar increase from 65:35 to equimolarity. The maximum activity of PPi:fructose 6-phosphate 1-phosphotransferase was 2.51 and 2.25 units per gram dry weight during storage at 2 and 8 degrees C, respectively. The temperature coefficient of this enzyme from potatoes kept at 2 or 8 degrees C was 2.12 and 2.48, respectively. The endogenous concentration of fructose 2,6-biphosphate increased from 0.15 to 1 nanomole per gram dry weight during storage at 2 and 4 degrees C but remained the same throughout storage at 8 degrees C. After exposure to 2 degrees C an initial increase in the concentration of PPi was observed from 4.0 to 5.6 nanomoles per gram dry weight. Pyrophosphate concentration did not change during storage at 4 degrees C but decreased slightly at 8 degrees C. All observed changes became annulled after transfer of cold stored tubers to 18 degrees C. These data strongly indicate that PPi:fructose 6-phosphate 1-phosphotransferase can be fully operational in cold stored potato tubers and the lack of increase in PPi concentration supports the functioning of this enzyme during sugar accumulation.
A simple model of ocean waves (1986)

We present a simple model for the surface of the ocean, suitable for the modeling and rendering of most common waves where the disturbing force is from the wind and the restoring force from gravity.It is based on the Gerstner, or Rankine, model where particles of water describe circular or elliptical stationary orbits. The model can easily produce realistic waves shapes which are varied according to the parameters of the orbits. The surface of the ocean floor affects the refraction and the breaking of waves on the shore. The model can also determine the position, direction, and speed of breakers.The ocean surface is modeled as a parametric surface, permitting the use of traditional rendering methods, including ray-tracing and adaptive subdivision. Animation is easy, since time is built into the model. The foam generated by the breakers is modeled by particle systems whose direction, speed and life expectancy is given by the surface model.To give designers control over the shape of the ocean, the model of the overall surface includes multiple trains of waves, each with its own set of parameters and optional stochastic elements. The overall "randomness" and "short-crestedness" of the ocean is achieved by a combination of small variations within a train and large variations between trains.Rendered examples of oceans waves generated by the model are given and a 10 second animation is described.