gebhart/patrepeval huggingface dataset:
An International Bibliography on Atomic Energy (1950)

Journal Article An International Bibliography on Atomic Energy Get access An International Bibliography on Atomic Energy. Vol. I. Political, Economic and Social Aspects. Preface by A. A. Sobolev . London, H.M.S.O. for United Nations, Atomic Energy Group, 1949. ix+45 pp. Bibliog. Index. 11′​′×812′​′⁠. 2s. 6d. Barbara Kyle Barbara Kyle Search for other works by this author on: Oxford Academic Google Scholar International Affairs, Volume 26, Issue 1, January 1950, Page 98, https://doi.org/10.2307/3016856 Published: 01 January 1950
Polyomavirus replication in mice: influences of VP1 type and route of inoculation (1991)

Patterns of polyomavirus replication and spread have been studied following inoculation of virus into newborn mice. Levels of virus replication in different tissues were followed in situ by using whole mouse section blots and immunoperoxidase staining for the major capsid protein VP1, as well as by tissue extraction and direct quantitation of viral DNA and infectious virus. Patterns of replication and spread were compared between the "high tumor" strain (inducing a high incidence of tumors) PTA and and the "low tumor" strain (inducing a low incidence of tumors) RA, following different routes of inoculation. The ability to induce a high tumor profile correlated with the ability to establish disseminated productive infection, with the kidney as a major site of amplification. Furthermore, results with PTA-RA recombinant viruses and site-directed mutants showed that the VP1 specificity of PTA, demonstrated earlier to be a critical determinant for induction of a high tumor profile (R. Freund, A. Calderone, C. J. Dawe, and T. L. Benjamin, J. Virol. 65:335-341, 1991), is also critical for amplification in the kidney and for establishment of disseminated infections.
Optimal Block Design for Asynchronous Wake-Up Schedules and Its Applications in Multihop Wireless Networks (2006)

In this paper, we consider the problem of designing optimal asynchronous wake-up schedules to facilitate distributed power management and neighbor discovery in multihop wireless networks. We first formulate it as a block design problem and derive the fundamental trade-offs between wake-up latency and the average duty cycle of a node. After the theoretical foundation is laid, we then devise a neighbor discovery and schedule bookkeeping protocol that can operate on the optimal wake-up schedule derived. To demonstrate the usefulness of asynchronous wake-up, we investigate the efficiency of neighbor discovery and the application of on-demand power management, which overlays a desirable communication schedule over the wake-up schedule mandated by the asynchronous wake-up mechanism. Simulation studies demonstrate that the proposed asynchronous wake-up protocol has short discovery time which scales with the density of the network; it can accommodate various traffic characteristics and loads to achieve an energy savings that can be as high as 70 percent, while the packet delivery ratio is comparable to that without power management
Sensing Home: A Cost-Effective Design for Smart Home via Heterogeneous Wireless Networks (2015)

The aging population has inspired the marketing of advanced real time devices for home health care, more and more wearable devices and mobile applications, which have emerged in this field. However, to properly collect behavior information, accurately recognize human activities, and deploy the whole system in a real living environment is a challenging task. In this paper, we propose a feasible wireless-based solution to deploy a data collection scheme, activity recognition model, feedback control and mobile integration via heterogeneous networks. We compared and found a suitable algorithm that can be run on cost-efficient embedded devices. Specifically, we use the Super Set Transformation method to map the raw data into a sparse binary matrix. Furthermore, designed front-end devices of low power consumption gather the living data of the habitant via ZigBee to reduce the burden of wiring work. Finally, we evaluated our approach and show it can achieve a theoretical time-slice accuracy of 98%. The mapping solution we propose is compatible with more wearable devices and mobile apps.
Advanced burst mode control to reduce the standby power of flyback converter (2013)

This paper we proposed advanced burst mode control technique to reduce the standby power consumption of the switch mode power supply (SMPS). To reduce the standby power consumption, most of the converter use burst mode or skip mode control technique. However Conventional standby mode control techniques have some problems such as audible noise and poor regulation. In proposed techniques, basically, the burst mode control technique is employed to reduce the fundamental switching frequency while limiting the peak drain current. But, in proposed technique, to improve the regulation characteristic, burst period of the proposed technique is shorter than that of the conventional burst mode technique. And also, to reduce the switching loss increase due to the short burst period, burst switching signal of the proposed technique is partially skipped. By using proposed advanced burst mode control technique, calculated standby power is 0.695W while standby power of the conventional burst mode control is 1.014W.
<title>Digital protection in a digital age</title> (1998)

Non-Impact printing is now widely used for most computer hard copy output applications. In the area of production of valuable documents such as title deeds, negotiable documents, passports, insurance policies and cover notes amongst others the flexibility of utilising this method of personalisation is often taken for granted. The benefits of economy, flexibility and speed tend to mask the risks associated with creating documents in this manner. Because of the ease with which alteration and replication can occur on high value documents, users have to protect material using costly lamination processes or look for other ways of securing the images created. Methods of digital protection have been developed that enable images to be protected by embedded digital fingerprints that are unique and hidden within the image itself. The applications of such devices are widespread and they can also be used as tools to detect the authenticity of products through covert protection on labels and packaging printed by digital, colour non-impact printers such as Indigo & Xeikon. this paper will review some of the products offered and how they can be applied as practical solutions to the problems faced. Also highlighted will be the expected performance requirements of such systems and how they compare with alternative solutions such as 2D bar codes, image scarring and secondary encoding routines.
Acoustic and visual signal based violence detection system for indoor security application (2012)

We propose an acoustic and visual signal based person-to-person violence detection system for indoor security application. A final decision is determined by fusing those detection results from each visual and acoustic detector. Information fusion is made with a Bayesian framework.
Superoxide anion is an endothelium-derived contracting factor (1989)

The calcium ionophore A23187 causes endothelium-dependent contractions in canine basilar arteries. Removal of the endothelium, or treatment with indomethacin or superoxide dismutase (SOD), prevented the endothelium-dependent excitatory effect of the calcium ionophore. Catalase and deferoxamine were without effect. Superoxide anion generated by xanthine plus xanthine oxidase in the presence of catalase caused contractions of the vascular smooth muscle, which were abolished by SOD or heat inactivation of xanthine oxidase. The A23187-induced production of prostaglandins F2 alpha and E2 and thromboxane B2 was abolished by the removal of endothelium and by treatment with indomethacin but was not affected by the presence of SOD plus catalase. These observations are consistent with the hypothesis that superoxide anion, rather than prostaglandins generated by hydroperoxidase activity of cyclooxygenase, is an endothelium-derived contracting factor in canine cerebral arteries.
Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid (2009)

Docosahexaenoic acid (DHA), an n-3 long chain polyunsaturated fatty acid (LC-PUFA), highly enriched in the central nervous system, is critical for brain development and function. It has been shown that DHA deficiency impairs cognitive performance whereas DHA supplementation improves the condition. However, the mechanisms underlying the role of DHA in brain development and function remain to be elucidated. By using transgenic fat-1 mice rich in endogenous n-3 PUFA, we show that increased brain DHA significantly enhances hippocampal neurogenesis shown by an increased number of proliferating neurons and neuritogenesis, evidenced by increased density of dendritic spines of CA1 pyramidal neurons in the hippocampus. Concurrently, fat-1 mice exhibit a better spatial learning performance in the Morris water maze compared with control WT littermates. In vitro experiments further demonstrate that DHA promotes differentiation and neurite outgrowth of neuronal cells derived from mouse ES cells and increases the proliferation of cells undergoing differentiation into neuronal lineages from the ES cells. These results together provide direct evidence for a promoting effect of DHA on neurogenesis and neuritogenesis and suggest that this effect may be a mechanism underlying its beneficial effect on behavioral performance.
Equalizers for multi-user detection in code division multiple access mobile radio systems (2002)

In code division multiple access (CDMA) systems transmitting over time-varying multipath channels, both intersymbol interference (ISI) and multiple access interference (MAI) arise. The conventional suboptimum receiver consisting of a bank of matched filters is often inefficient because interference is treated as noise. The optimum multi-user detector is too complex to be implemented at present. Four suboptimum detection techniques based on zero forcing (ZF) and minimum mean square error (MMSE) equalization with and without decision feedback (DF) are presented and compared. They combat both ISI and MAI. The computational complexity of all four equalizers is essentially the same and they are independent of the size of the data symbol alphabet. It is shown that all four equalizers considerably outperform the conventional receiver. The MMSE equalizers are superior to the corresponding ZF equalizers. Furthermore, the equalizers with DF perform better than the corresponding equalizers without DF. An algorithm termed channel sorting is introduced to reduce the impairing effect of error propagation on the equalizers with DF.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit (2017)

The 3' untranslated regions (UTRs), located at the end of mRNA molecules, are believed to play a role in RNA replication and/or protein translation. Mutations in the tyrosinase (Tyr) gene are known to cause recessive albinism in humans and other species. In this study, to test whether the CRISPR/Cas9 system works on the mutation of the UTRs regulatory region in rabbit, the 3' UTR of the rabbit Tyr gene was deleted by a dual sgRNA directed CRISPR/Cas9 system. As expected, gray coat color and reduced melanin in hair follicles and irises was found in the mutated rabbit, thus increasing confidence in the association of the mutation of the Tyr 3' UTR with graying in rabbit. The graying phenotype was also found in the F1 generation, suggesting that the mutated allele can be stably inherited by the offspring. Thus, we provide the first evidence that reduced melanin and graying can be caused by deletion of the Tyr 3' UTR in rabbits. Additionally, CRISPR/Cas9-mediated large fragment deletions can facilitate genotype to phenotype studies of UTRs or non-coding RNAs in future.
Gas Analysis (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas AnalysisL. K. NashCite this: Anal. Chem. 1950, 22, 1, 108–121Publication Date (Print):January 18, 1950Publication History Published online1 May 2002Published inissue 18 January 1950https://pubs.acs.org/doi/10.1021/ac60037a026https://doi.org/10.1021/ac60037a026research-articleACS PublicationsRequest reuse permissionsArticle Views79Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Effect of Peripherally Inserted Central Catheter (PICC) Valve Technology on Catheter Occlusion Rates - The ‘ELeCTRiC’ Study (2012)

Valved PICCs do not appear to influence PICC occlusion rates.
Testable Design for Adaptive Linear Equalizer in High-Speed Serial Links (2006)

This paper describes a novel DfT solution to the adaptive linear equalizer in the receiver of a high-speed serial link. We first summarize various equalization architectures, adaptive algorithms, circuit implementations, and their variations to which the proposed solution can be applied. The solution addresses the observability problem of the equalizer and results in a testable design that can be easily characterized and cost-effectively tested in the production line. To validate the proposed method, we conducted experiments for examples with various injected faults, for which the conventional approach of examining the eye opening at the output of the equalizer results in poor fault coverage. Simulation results demonstrate that the proposed method has a significantly higher coverage for those hard-to-detect faults.
Label-free Single Molecule Detection Using Microtoroid Optical Resonators (2015)

Detecting small concentrations of molecules down to the single molecule limit has impact on areas such as early detection of disease, and fundamental studies on the behavior of molecules. Single molecule detection techniques commonly utilize labels such as fluorescent tags or quantum dots, however, labels are not always available, increase cost and complexity, and can perturb the events being studied. Optical resonators have emerged as a promising means to detect single molecules without the use of labels. Currently the smallest particle detected by a non-plasmonically-enhanced bare optical resonator system in solution is a 25 nm polystyrene sphere(1). We have developed a technique known as Frequency Locking Optical Whispering Evanescent Resonator (FLOWER) that can surpass this limit and achieve label-free single molecule detection in aqueous solution(2). As signal strength scales with particle volume, our work represents a > 100x improvement in the signal to noise ratio (SNR) over the current state of the art. Here the procedures behind FLOWER are presented in an effort to increase its usage in the field.
Elevated Vascular Endothelial Growth Factor Production in Islets Improves Islet Graft Vascularization (2004)

Successful islet transplantation depends on the infusion of sufficiently large quantities of islets, of which only approximately 30% become stably engrafted. Rapid and adequate revascularization of transplanted islets is important for islet survival and function. Delayed and insufficient revascularization can deprive islets of oxygen and nutrients, resulting in islet cell death and early graft failure. To improve islet revascularization, we delivered human vascular endothelial growth factor (VEGF) cDNA to murine islets, followed by transplantation under the renal capsule in diabetic mice. Diabetic animals receiving a marginal mass of 300 islets that were pretransduced with a VEGF vector exhibited near normoglycemia. In contrast, diabetic mice receiving an equivalent number of islets that were transduced with a control vector remained hyperglycemic. Immunohistochemistry with anti-insulin and anti-CD31 antibodies revealed a relatively higher insulin content and greater degree of microvasculature in the VEGF vector-transduced islet grafts, which correlated with significantly improved blood glucose profiles and enhanced insulin secretion in response to glucose challenge in this group of diabetic recipient mice. These results demonstrate that VEGF production in islets stimulates graft angiogenesis and enhances islet revascularization. This mechanism might be explored as a novel strategy to accelerate islet revascularization and improve long-term survival of functional islet mass posttransplantation.
The Effects of Anionic and Cationic Surfactants on the Ion Flotation of Cd2+ (1975)

Abstract The ion flotation of Cd2+ ions has been investigated from the surface chemical point of view in comparison with the case of Cu2+ ions reported previously. The effects of the change in the pH, the anionic and cationic surfactants, and bentonite on the flotation rate have also been studied. Sodium α-sulfolaurate proved to be one of the best surfactants among the anionic surfactants used for removing Cd2+ ions, showing as high as a 97% removal. About 97% of the Cd2+ ions could be floated in the region of pH 11.3 when a cationic surfactant was used with bentonite, regardless of the exact surfactant used. The addition of bentonite reduced the foam formation and liquid hold-up, resulting in effective bubble flotation. This behavior was as a whole similar to that of Cu2+ ions. However, in all the flotation systems tested, the flotation rate increased sharply at about pH 8, and the flotation rate vs. pH curve for Cd2+ shifted towards a more alkaline region than that for Cu2+, because of the stronger basic nature of the former. Also, the flotation rate of Cd2+ ions for the Cd2+-anionic surfactant systems attained a steady value after about 7 min, longer than the 2-min gas flow required in the case of Cu2+ ion flotation. The adjustment of the pH using ammonia gave a lower rate of flotation than in the case of flotation using sodium hydroxide.
Handbook of Pharmaceutical Manufacturing Formulations: Volume One, Compressed Solid Products (2009)

Providing methodologies that can serve as a reference point for new formulations, the second volume covers uncompressed solids, which include formulations of powders, capsules, powders ready for reconstitution, and other similar products.Highlights from Uncompressed Solid Products, Volume Two include:the fundamental issues of good manufacturin
Molded Monolithic Rod of Macroporous Poly(styrene-<i>co</i>-divinylbenzene) as a Separation Medium for HPLC of Synthetic Polymers:  “On-Column” Precipitation−Redissolution Chromatography as an Alternative to Size Exclusion Chromatography of Styrene Oligomers and Polymers (1996)

A process for the separation of styrene oligomers and polymers by size and composition using a novel separation medium has been demonstrated. The process involves precipitation of the macromolecules on the molded macroporous rod columns, followed by progressive elution utilizing a simple gradient of the mobile phase. Molded macroporous rod columns are ideally suited for this technique because convection through the large pores of the rod enhances the mass transport of large analyte molecules and accelerates the separation process. Styrene oligomers and polymers are separated in a 50-mm x 8-mm-i.d. column using a solvent gradient composed of a poor solvent such as water, methanol, or acetonitrile and increasing amounts of a good solvent, tetrahydrofuran. Excellent separations are obtained, demonstrating that precipitation-redissolution can be a suitable alternate to size exclusion chromatography (SEC) of some polymers. Compared to SEC, the gradient elution separation can be achieved at higher flow rates in a much shorter time. Precipitation-redissolution with gradient elution can also be used for the separation of copolymers, for which the process is controlled not only by molecular weight but also by the composition of the copolymers.
Sequential modification of translation initiation factor eIF4GI by two different foot-and-mouth disease virus proteases within infected baby hamster kidney cells: identification of the 3Cpro cleavage site (2004)

Infection of cells by foot-and-mouth disease virus (FMDV) causes the rapid inhibition of cellular cap-dependent protein synthesis that results from cleavage of the translation initiation factor eIF4G, a component of the cap-binding complex eIF4F. Two FMDV proteins, the leader (L) and 3C proteases, have been shown individually to induce cleavage of eIF4GI at distinct sites within baby hamster kidney (BHK) cells. Here, sequential cleavage of eIF4GI by the L and 3C proteases was demonstrated in FMDV-infected BHK cells. The FMDV 3C cleavage site within hamster eIF4GI was localized to a small region (about 40 aa) of the protein, between the sites cleaved by the poliovirus 2A protease and the human immunodeficiency virus type 2 protease. Human eIF4GI was found to be resistant to the action of the FMDV 3C protease. On the basis of amino acid sequence alignments, it was predicted and then verified that substitution of a single amino acid residue within this region of human eIF4GI conferred sensitivity to cleavage by the FMDV 3C protease within cells. Full-length eIF4GI and both forms of the C-terminal cleavage product must be capable of supporting the activity of the FMDV internal ribosome entry site in directing translation initiation.
Cytopenia and leukocyte recovery shape cytokine fluctuations after myeloablative allogeneic hematopoietic stem cell transplantation (2011)

Our results indicate that both recipient-related and donor-related factors contribute to the changes in cytokine levels in the recipient following allogeneic hematopoietic stem cell transplantation. The study reported here was performed using plasma samples drawn from patients enrolled in the ClinicalTrials.gov-registered trials NCT00467961 and NCT00378534.
Targeting paediatric acute lymphoblastic leukaemia: novel therapies currently in development (2010)

Modifications to the treatment of acute lymphoblastic leukaemia (ALL) in children have led to a dramatic increase in survival in the past 40 years. Despite this success, a significant subset of paediatric leukaemia patients either relapse or fail to ever achieve a complete remission. Additionally, some patients necessitate treatment with intensified chemotherapy regimens due to clinical or laboratory findings which identify them as high risk. These patients are unlikely to respond to further minor adjustments to the dosing or timing of administration of the same chemotherapy medications. Many novel targeted therapies for the treatment of childhood ALL provide potential mechanisms to further improve cure rates, and provide the possibility of minimizing toxicity to non-malignant cells, given their specificity to malignant cell phenotypes. This article explores many of the potential targeted therapies in varying stages of development, from those currently in clinical trials to those still being refined in the research laboratory.