gebhart/patrepeval huggingface dataset:
Multianalyte Antibiotic Detection on an Electrochemical Microfluidic Platform (2016)

The excessive use of antibiotics in human and veterinary medicine causes the emergence of multidrug resistant bacteria. In this context, the surveillance of many different antibiotics provokes a worldwide challenge. Hence, fast and versatile multianalyte single-use biosensors are of increasing interest for many fields such as medical analysis or environmental and food control. Here we present a microfluidic platform enabling the electrochemical readout of up to eight enzyme-linked assays (ELAs), simultaneously. To demonstrate the applicability of this platform for the surveillance and monitoring of antibiotics, we used highly sensitive biomolecular sensor systems for the simultaneous detection of two commonly employed antibiotic classes tetracycline and streptogramin. Thus, microfluidic channel networks are designed, comprising distinct numbers of immobilization sections with a very low volume of 680 nL each. These passively metered sections can be actuated separately for an individual assay procedure. The limits of detection (LOD) are determined, with high precision, to 6.33 and 9.22 ng mL<sup>-1</sup> for tetracycline and pristinamycin, respectively. The employed channel material, dry film photoresist (DFR), allows an easy storage of preimmobilized assays with a shelf life of at least 3 months. Multianalyte measurements in a complex medium are demonstrated by the simultaneous detection of both antibiotics in spiked human plasma within a sample-to-result time of less than 15 min.
THE VELOCITY OF ADSORPTION PROCESSES AND THE PROBLEM OF PROMOTER ACTION (1931)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE VELOCITY OF ADSORPTION PROCESSES AND THE PROBLEM OF PROMOTER ACTIONHugh S. Taylor and Arthur T. WilliamsonCite this: J. Am. Chem. Soc. 1931, 53, 2, 813–814Publication Date (Print):February 1, 1931Publication History Published online1 May 2002Published inissue 1 February 1931https://pubs.acs.org/doi/10.1021/ja01353a508https://doi.org/10.1021/ja01353a508research-articleACS PublicationsRequest reuse permissionsArticle Views29Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A dynamic-programming approach to continuous-review obsolescent inventory problems (1997)

Inventory models of modern production and service operations should take into consideration possible exogenous failures or the abrupt decline of demand resulting from obsolescence. This article analyzes continuous-review versions of the classical obsolescence problem in inventory theory. We assume a deterministic demand model and general continuous random times to obsolescence (“failure”). Using continuous dynamic programming, we investigate structural properties of the problem and propose explicit and workable solution techniques. These techniques apply to two fairly wide (and sometimes overlapping) classes of failure distributions: those which are increasing in failure rate and those which have finite support. Consequently, several specific failure processes in continuous time are given exact solutions. © 1997 John Wiley & Sons, Inc. Naval Research Logistics 44: 757–774, 1997
Lines on Rupert Brooke (1953)

Lines on Rupert Brooke Get access Ed Ed Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume CXCVIII, Issue jun, 1 June 1953, Page 270, https://doi.org/10.1093/nq/CXCVIII.jun.270c Published: 01 June 1953
Environmental Awareness Projects for Children (1972)

(1972). Environmental Awareness Projects for Children. School Health Review: Vol. 3, No. 4, pp. 19-22.
Understanding the Roles and Uses of Web Tutorials (2021)

In this paper we identify roles and uses of web-based tutorials through an examination of tutorials’ comments sections. Through this analytical lens, we find that web tutorials serve a variety of needs, providing: in-task help for users with an immediate, specific goal to accomplish; a means for users to proactively expand their repertoire of skills; and an opportunity for novices to shadow and experience an expert’s work practices. We also find a number of emergent practices in tutorial comments. Users post “help-me” stack traces, a type of comment useful for debugging tutorial content; use comments sections as opportunistic support forums; and turn to comments sections for social and technical validation of their personal skill sets. Collectively, these findings enrich existing perspectives on web-based tutorials and argue for new mechanisms to support these various use cases.
Flavonoids as Antioxidants (2000)

Flavonoids are phenolic substances isolated from a wide range of vascular plants, with over 8000 individual compounds known. They act in plants as antioxidants, antimicrobials, photoreceptors, visual attractors, feeding repellants, and for light screening. Many studies have suggested that flavonoids exhibit biological activities, including antiallergenic, antiviral, antiinflammatory, and vasodilating actions. However, most interest has been devoted to the antioxidant activity of flavonoids, which is due to their ability to reduce free radical formation and to scavenge free radicals. The capacity of flavonoids to act as antioxidants in vitro has been the subject of several studies in the past years, and important structure-activity relationships of the antioxidant activity have been established. The antioxidant efficacy of flavonoids in vivo is less documented, presumably because of the limited knowledge on their uptake in humans. Most ingested flavonoids are extensively degraded to various phenolic acids, some of which still possess a radical-scavenging ability. Both the absorbed flavonoids and their metabolites may display an in vivo antioxidant activity, which is evidenced experimentally by the increase of the plasma antioxidant status, the sparing effect on vitamin E of erythrocyte membranes and low-density lipoproteins, and the preservation of erythrocyte membrane polyunsaturated fatty acids. This review presents the current knowledge on structural aspects and in vitro antioxidant capacity of most common flavonoids as well as in vivo antioxidant activity and effects on endogenous antioxidants.
A CCD imaging and analysis system for the VG HB5 STEM (1986)

A liquid nitrogen cooled charge coupled device (CCD) camera with DEC 11-73 computer has been fitted to the Vacuum Generators HB5 scanning transmission electron microscope (STEM). Typically, diffraction patterns are produced in the VG HB5 STFM by rocking the beam on the sample or alternatively by rastering the electrons that emerge from the sample and displaying the resultant scanned image on the CRT. The image is often noisy because the beam current is small (≈10 10 a) and the range of interesting intensities is large.
Colloidal Spray Deposition Technique for the Processing of Thin Film Solid Oxide Fuel Cells (1999)

No abstract prepared.
Recent Italian cinema: Spaces, contexts, experiences, by Tiziana Ferrero-Regis, Leicester, Troubador, 2009, xxxi + 296 pp., £14.95 (paperback), ISBN 978-1-848-76085-1 (2011)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Improving fatigue resistance of Pb(Zr,Ti)O3 thin films by using PbZrO3 buffer layers (2006)

Ferroelectric Pb(Zr0.52Ti0.48)O3 (PZT) thin films with PbZrO3 (PZ) buffer layers were prepared on Pt(111)∕Ti∕SiO2∕Si(100) substrates using a hybrid rf magnetron sputtering and sol-gel process. Texture of PZT films was found to depend on Pb content of PZ buffer layers. Buffered PZT films displayed comparable ferroelectric properties (2Pr=38–53μC∕cm2,2Ec=136–170kV∕cm) with unbuffered PZT. Asymmetric leakage current and fatigue behavior with superior fatigue resistance was observed in PZ buffered PZT compared to unbuffered films. PZ buffer layers were found to affect crystallization and texture of PZT, and act as a capacitive interface layer possibly blocking charge injection from electrodes.
Computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model (2018)

Valvular heart disease is a major cause of morbidity and mortality worldwide. Current heart valve prostheses have considerable clinical limitations due to their artificial, nonliving nature without regenerative capacity. To overcome these limitations, heart valve tissue engineering (TE) aiming to develop living, native-like heart valves with self-repair, remodeling, and regeneration capacity has been suggested as next-generation technology. A major roadblock to clinically relevant, safe, and robust TE solutions has been the high complexity and variability inherent to bioengineering approaches that rely on cell-driven tissue remodeling. For heart valve TE, this has limited long-term performance in vivo because of uncontrolled tissue remodeling phenomena, such as valve leaflet shortening, which often translates into valve failure regardless of the bioengineering methodology used to develop the implant. We tested the hypothesis that integration of a computationally inspired heart valve design into our TE methodologies could guide tissue remodeling toward long-term functionality in tissue-engineered heart valves (TEHVs). In a clinically and regulatory relevant sheep model, TEHVs implanted as pulmonary valve replacements using minimally invasive techniques were monitored for 1 year via multimodal in vivo imaging and comprehensive tissue remodeling assessments. TEHVs exhibited good preserved long-term in vivo performance and remodeling comparable to native heart valves, as predicted by and consistent with computational modeling. TEHV failure could be predicted for nonphysiological pressure loading. Beyond previous studies, this work suggests the relevance of an integrated in silico, in vitro, and in vivo bioengineering approach as a basis for the safe and efficient clinical translation of TEHVs.
666. Oxidation of organic compounds by nitrous oxide. Part I (1951)

The first page of this article is displayed as the abstract.
Small-polaron versus band conduction in some transition-metal oxides (1970)

Abstract In this paper an attempt is made to establish the nature of free charge carriers and of charge carriers bound to centres in p-type NiO, CoO and MnO and in n-type MnO and α-Fe2O3. For free charge carriers, d.c. conductivity, Seebeck coefficient and Hall effect are considered. Effects arising from inhomogeneous conduction and impurity conduction are discussed. Impurity conduction appears to have a strong influence on transport properties in the case of α-Fe2O3, less so in NiO, whereas no influence of this effect has been found in CoO and MnO. It is shown that NiO and CoO do not exhibit the features characteristic of small-polaron conductors but rather can be consistently conceived of as large-polaron band semiconductors. It is suggested that magnetic resistance due to exchange coupling between charge-carrier spin and cation spins plays an important role. The anomalous behaviour of the Hall effect in NiO and α-Fe2O3 is extensively discussed. In contradistinction to NiO, CoO and n-type MnO, free charge carriers in p-type MnO seem to have small-polaron character. For charge carriers bound to centres, dielectric loss, high-frequency conduction and optical absorption are considered. The dielectric loss data relate to Li or Na centres in NiO, CoO and MnO and to Ti, Zr, Sn, Ta, Nb and presumably oxygen vacancy centres in α-Fe2O3. It is concluded from the dependence of dielectric loss on frequency and temperature that bound charge carriers are small polarons. It is shown for the cases of NiO and α-Fe2O3 that apart from small-polaron effects, disorder due to locally varying electric fields determines the nature of dielectric loss. The small-polaron character of bound charge carriers in NiO is corroborated by the behaviour of high-frequency conduction and optical absorption due to centres and also by the magnitude of impurity conduction.
Temperature coefficient of resistance based on conductive rubber filled by carbon black (2012)

Conductive composites are consisting of carbon particles(CB3100) and silicone rubber matrix.The temperature coefficient of resistance(TCR) based on conductive silicon rubber was analyzed for the dosage of filler,and studied the different filler blend in the conductive composites.Analysis the resistivity calculation model of conductive carbon black/silicone rubber which based on the theory of tunneling,the TCR model has been calculated,combined with experiments: temperature effects the TCR of the conductive carbon black/silicone rubber,by act on resistivity of conductive carbon black/silicone rubber;the volume thermal expansion of matrix increased the resistivity of composites,the positive TCR of conductive composites enhanced;tunnel effect between carbon black particles reduces the resistivity of composite materials,the negative TCR of conductive composites enhanced.By adding a small amount of carbon nanotubes in the carbon black/silicone rubber,due to the synergetic effect of carbon nanotubes and carbon black in a rubber system,conductivity and stability of conductive composites enhanced.
Application virtualization techniques for malware forensics in social engineering (2015)

There is an increased trend in information insecurity, online fraud and social engineering activities today as a result of high dependence on the Internet and social networks for communication, advertisement of products and services, etc. Malwares are most times, deliberately programmed as worms to appear as flash messages, online games, gift awards and in many other attractive forms for the user to access just at the click of a button. Several methods have been applied to minimize these infiltrations which include firewalls and anti-viruses. However when confronted with a system infected with malware, a person's ability to investigate the system successfully depends on his knowledge, experience, and toolset. This is where there is a conundrum. People tend to avoid dealing with malware cases on their own due to inexperience and lack of knowledge but would rather outsource it to IT professionals either hired at that particular instance or employed within their organization. However, through careful preparation one can acquire knowledge, experience, and toolset that can eventually lead to working malware cases. The various procedures for investigating infiltrations into supposedly secure networks and computer systems are presented in this paper.
Impact on Power System Frequency Dynamics from an HVDC Transmission System With Converter Stations Controlled as Virtual Synchronous Machines (2019)

This paper evaluates the operation of an HVDC interconnection for providing virtual inertia and the impact on the power system frequency dynamics when one or both the converter terminals are controlled as a virtual synchronous machine (VSM). The analysis aims at assessing the performance of the inertia support from a power system perspective by studying the impact on the frequency nadir and the Rate-of Change-of-Frequency (RoCoF) of two asynchronous power system equivalents. It is demonstrated how the dc voltage control can be integrated with the VSM-based control when both converter terminals should be controlled to provide inertia support, but it is also found that this may require additional capacitance to ensure sufficient stability margins. Simulations in PowerFactory are presented for a case with two asynchronous power system equivalents connected by an HVDC transmission scheme modelled with parameters based on the planned Nordlink connection between Norway and Germany. The results confirm the beneficial effects of the inertia support on the frequency dynamics and demonstrate how the VSM-based control provides a clear improvement of the frequency nadir compared to traditional power-frequency droop control.
Simulation of CO2 Recovery System from Flue Gas by Honeycomb Type Adsorbent: II (Optimization of CO2 Recovery System and Proposal of Actual Plant) (2006)

地球温暖化の主要な原因の一つになっている，火力発電所からの排ガスに含有されるCO2を，ハニカム型ゼオライトを充填した回転式吸着塔を用いたTSA方式で除去・濃縮するシステムについて最適化のためのシミュレーション計算を行った．本研究では，各パラメータがCO2回収率と所要加熱量に及ぼす影響を検討することにより，最適条件の選定を行った．この結果，14000 m3 (STP)·h−1の排ガスを処理する装置として，直径14.5 m，層高0.5 mのロータ回転型吸着層を用いると，最適操作条件として，加熱再生ガス温度：423 K，再生ガス流量：80000 m3 (STP)·h−1，回転数：3–4 rphが得られた．なお，若干性能は低下するが，上記仕様の装置で70000 m3 (STP)·h−1の排ガス処理も可能であることがわかった．また，本システムにより排ガス中のCO2濃度（13.5%程度）を1回の操作で90%以上にまで濃縮できることがわかった．さらに，これらの結果に基づいて，処理ガス流量が180万m3 (STP)·h−1の時の実機の装置イメージを提案した．この場合の吸着層寸法は，直径14.5 m，層高0.5 mを26段たてに積重ねる構造とすると，全塔高は26 m程度と予想される．
Copy Number Analysis of the Murine Platelet Proteome Spanning the Complete Abundance Range (2014)

Knowledge of the identity and quantity of expressed proteins of a cell type is a prerequisite for a complete understanding of its molecular functions. Mass-spectrometry-based proteomics has allowed the identification of the entire protein complement of yeast and the close-to-complete set of proteins expressed in mammalian cell lines. Using recent technological advances, we here characterized the proteome of murine platelets, key actors in mediating hemostasis and thrombosis. We accurately measured the absolute protein concentrations of 13 platelet proteins using SILAC-protein epitope signature tags and used them as reference points to estimate the copy numbers of all proteins of the platelet proteome. To distinguish contaminants such as plasma or erythrocyte proteins from true platelet proteins, we monitored protein abundance profiles across multiple purification steps. In total, we absolutely quantified 4,400 platelet proteins, with estimated copy numbers ranging from less than 10 to about a million per cell. Stoichiometries derived from our data correspond well with previous studies. Our study provides a close-to-complete reference map of platelet proteins that will be useful to the community, for instance, for interpreting mouse models of human platelet diseases.
Molecular and phylogenetic characterization of the sieve element occlusion gene family in Fabaceae and non-Fabaceaeplants (2010)

The unexpected occurrence of forisome-like genes in non-Fabaceae plants may indicate that these proteins encode species-specific P-proteins, which is backed up by the phloem-specific expression profiles. The conservation of gene structure, the presence of specific motifs and domains and the genomic synteny argue for a common phylogenetic origin of forisomes and other P-proteins.
Emergent faces in crystal etching (1994)

The time development of emergent faces in crystal etching is investigated. We present and discuss a novel computational approach, based on an intuitive geometrical derivation, for predicting an etched shape given an initial polygonal (mask) shape and a diagram of etch rate as a function of orientation. A two-dimensional geometric model is derived which determines the etched shape as a function of time. The model is both intuitive and easy to implement manually or by computer. Because the model is intuitive in nature, some results can be obtained from only partial information. In addition, the model is a first step in the transition from analysis to design. Rather than predicting the etched shape for a given original shape, often what is desired is the original mask shape needed to produce a particular etched shape. This inversion process is carried out for some special cases. The concepts of equilibrium or eigen shapes (Eshapes), limit shapes, and time scaling are introduced. Model predictions are compared with experimental results. The extension from two dimensions to three is also introduced.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Catalytic Decomposition of Formic Acid on Metal Oxides (1972)

Abstract Studies on the decomposition of formic acid were initiated during the first decade of the present century by Mailhe and Sabatier [1], using metals and metal oxides. These authors were concerned primarily with the selectivity of their catalysts, i.e., their ability to favor one of the reactions possible for the decomposition of formic acid (Eq. 1).
Extract of <i>Fagara zanthoxyloides</i> Root in Sickle Cell Anaemia (1975)

Following the demonstration of the ability of aqueous extracts of Fagara zanthoxyloides root to reverse sickling, toxicological studies in duck and chick embryos as well as in mice have shown these extracts to be non-toxic. Preliminary clinical trials demonstrated a significant diminution in the incidence of painful episodes in Fagara-treated individuals.
GAS41, a Highly Conserved Protein in Eukaryotic Nuclei, Binds to NuMA (2000)

The yeast two-hybrid system was used to identify binding partners of NuMA, a component of the nuclear matrix in interphase cells. By using the C-terminal half of NuMA as bait, a human cDNA sequence coding for a 223-amino acid protein with a non-helical N-terminal domain and a C-terminal alpha-helical portion was identified and fully sequenced. It was identical to GAS41, a sequence amplified in human gliomas. The sequence of the homologous Drosophila protein was established, and the alignment for GAS41 from nine different species showed that GAS41 is a general eukaryotic protein found in species as diverse as Arabidopsis, Drosophila, Caenorhabditis elegans, yeast, and man. Northern blot analysis showed a single transcript in eight human tissues. A polyclonal antibody to GAS41 showed a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. A GFP-GAS41 fusion protein displayed equivalent patterns. In vitro GAS41 bound to the C-terminal part of the rod region of NuMA, as shown by dot overlay and by surface plasmon resonance measurements. The K(d) of the complex was 2 x 10(-)(7) m. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors found as fusion proteins in some acute leukemias. The NuMA/GAS41 interaction may provide a link between nuclear structure and gene expression.
Mechanical and Hydrothermal Stabilities of Aged Periodic Mesoporous Organosilicas (2003)

Methylene-, ethylene-, and phenylene-bridged periodic mesoporous organosilicas (PMOs) synthesized with nonionic alkylethylene oxide templates exhibited significantly better mechanical and hydrothermal stabilities than periodic mesoporous silica. Synthesis of PMOs utilized the acid-catalyzed hydrolysis and condensation of bis(triethoxysilyl) precursors around supramolecular polyoxyethylene(10) stearyl ether (Brij 76) templates. Nitrogen gas sorption, thermogravimetry, and X-ray diffraction have been used to characterize the effects of aging, mechanical compression, and hydrothermal treatment on these materials. Both as-synthesized composites containing surfactant templates and extracted PMOs showed no degradation after 10 months. The enhanced stability of these nanoporous organosilicas relative to meoporous silica makes them potential candidates for use in advanced catalysis and adsorption applications.
Effect of Surface Carbon Structure on the Electrochemical Performance of LiFePO[sub 4] (2003)

No abstract prepared.