gebhart/patrepeval huggingface dataset:
Remarks on the Ciarlet-Raviart mixed finite element. (1996)

. This paper derives a new scheme for the mixed finite element method for the biharmonic equation in which the flow function is approximated by piecewise quadratic polynomial and vortex function by piecewise linear polynomials. Assuming that the partition, with triangles as elements, is quasi-uniform, then the proposed scheme can achieve the approximation order that is observed by the Ciarlet-Raviart mixed finite element when approximating the flow function and the vortex functions by piecewise quadratic polynomials. Key words. Ciarlet-Raviart mixed finite element, biharmonic problem. AMS subject classification. 65L60. 1. Review of the Ciarlet-Raviart mixed element scheme. Consider the biharmonic problem (with clamped boundary conditions) ( # 2 # = f, in# , # = ## #n = 0 on ## , (1.1) where the domain# is a convex polygon in R 2 . Let by H s ( ## denote the Sobolev space, let ## s denote its norm, and let ## 0 denote the norm of the space L 2(##1 Let H -1(## be the...
Architecture, applications, and design of a video FIR filter IC (2003)

The architecture, salient applications, and design method of an experimental video finite impulse response (FIR) digital filter integrated circuit (IC) is described. The authors have used an improved multiplier/accumulator architecture to achieve high throughput and have included hardware to enhance testability. This chip covers many of the frequency filtering, decimation/interpolation, and other one- and two-dimensional digital signal processing applications. There are facilities on the device to allow cascading of several ICs for building higher-order filters or for obtaining other configurations. This very high performance programmable digital FIR filter circuit has been fabricated in 0.9- mu m CMOS technology using automatic custom CAD tools. Using such tools as automatic netlist optimizer and automatic layout, the authors created the layout mask from the block diagram in approximately 10 weeks. Although the device was targeted for video frequency applications, it functioned well beyond that range.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
DNA Microarrays: Tools for the 21st Century (2004)

Profiling of gene expression patterns with microarray technology is widely used in both basic and applied research. DNA microarrays have also shown great promise in clinical medicine and are paving the way toward effective pharmaceutical drug discovery and individualized drug regimens. With growing utilization of this high-throughput technology, new applications are making headlines on a regular basis. This review aims to outline the pros and cons of this methodology and direct the reader towards available useful resources. Various major array formats such as high-density oligonucleotide arrays and spotted cDNA arrays are examined, and advantages and options for using each format are presented. Factors important for the design and analysis of microarray experiments are also discussed.
<title>Design and development of receptor-avid peptide conjugates for in-vivo targeting of cancer</title> (1999)

Radiometallated peptides that exhibit high specificity for cognate receptors over expressed on cancer cells offer important potential as site-directed diagnostic and therapeutic radiopharmaceutical. The formation of effective radioactive drugs for specific in vivo targeting of cancerous tumors is being facilitated by the integration of novel chelation strategies and receptor-avid derivatives. Significant efforts are being made to design Technetium-99m labeled for diagnostic imaging of cancerous tumors for use in conjunction with Single Photon Emission Tomography instrumentation in nuclear medicine. Receptor avid radiopharmaceutical are also being developed that utilize other radionuclides for imaging and therapeutic applications. Despite the technological challenges that must be overcome, radiolabeled receptor avid peptide conjugates are providing promising site-directed targeting agents for the assessment and treatment of cancerous tumors in humans.
Network text editor (NTE) (1997)

IP Multicast, Lightweight Sessions and Application Level Framing provide guidelines by which multimedia conferencing tools can be designed, but they do not provide specific solutions. In this paper, we use these design principles to guide the design of a multicast based shared editor, and examine the consequences of taking a loose consistency approach to achieve good performance in the face of network failures and losses.
On automatic generation of RTL validation test benches using circuit testing techniques (2003)

In this paper, we examine how good validation test benches can be automatically generated starting from the RTL description of a circuit. We develop our methodology based on extensive experiments performed with several popular benchmarks as well as industrial circuits.
Cache automaton (2017)

Finite State Automata are widely used to accelerate pattern matching in many emerging application domains like DNA sequencing and XML parsing. Conventional CPUs and compute-centric accelerators are bottlenecked by memory bandwidth and irregular memory access patterns in automata processing.
Induction over large data bases (1979)

These findings may have implications for quantitative analysis of the newborn EEG, including the EEG of babies with hypoxic ischaemic encephalopathy.
ChemInform Abstract: Facile Synthesis of Substituted Methylamides from Acetoxymethylamides. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A review on high frequency resonant inverter technologies for wireless power transfer using magnetic resonance coupling (2014)

Research on developing the applications of Wireless Power Transfer system (WPTS) has been increased considerably for the last few years. Plug-in Hybrid Electrical Vehicle & Electric vehicle charging is one of them. Due to operational and environmental benefit charging of these vehicles via Wireless Power Transfer (WPT) has been considered in academic and industrial research to obtain an environmental friendly future transportation system. Among various types of WPT system, Magnetic Resonant Coupling WPT (MRCWPT) has been appeared as an attractive technology for mid-range (200-300 mm), medium power (>2 kW) electric vehicle charging application. High frequency resonant Inverters play an important role in efficient MRCWPT vehicle charging system. Among different resonant inverter topology, class E and its variant have shown the potentiality in this type of WPT system due to its circuit simplicity, efficient high frequency operation by zero voltage switching (ZVS) etc. Along with this inverter some other potential inverter topologies have been discussed based on the last 5-6 years literature. Simulation results of class φ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> inverter which has currently been modifying by the authors have been presented to confirm the potentiality of this type of inverter and design challenges have been addressed. A practical robust WPT vehicle charging system (based on literature) has been presented for a charging gap of 200-300 mm. Authors are currently working on designing resonant inverter topology for this type of WPT vehicle charging system.
Dual functional molecular imaging probe targeting CD20 with PET and optical imaging (2009)

The present study aimed to develop a monoclonal antibody (mAb)-based double functional probe for PET and near-infrared fluorescence (NIRF) targeting CD20 and to cross validate the targeting efficacy of this dual functional probe. NuB2, anti CD20 mAb was conjugated with Alexa Fluor 750 and 64Cu through DOTA chelator. PET and NIRF imaging was carried out at 30 min and 24 h post-injection with 64Cu-DOTA-NuB2-Alexa Fluor 750 in CD20 positive Raji lymphoma-bearing mice. Fluorescence intensity and radio-activity were studied by ex vivo biodistribution study at 30 min, 24 and 48 h after injection. Raji tumor showed significantly higher uptake of DOTA-NuB2-Alexa Fluor 750 than that of DOTA-Alexa Fluor 750 (p<0.05). Significant correlation was obtained between the organ-to-muscle ratios measured by the radioactivity and fluorescence intensity (p<2.2e-16, r=0.94). Our findings demonstrate the effectiveness and feasibility of preparing an effective mAb-based dual functional imaging agent for PET and NIRF targeting the CD20 expression in lymphoma.
The Anterior Surgical Approach to the Cervical Spine: The Cloward Procedure: Past, Present, and Future (1988)

From the Departments of Neurosurgery, Queens Medical Center, and the John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii
Rotary Power Loss Machine (1959)

Abstract Rubberlike polymeric materials, particularly in the technical form when compounded with carbon black, are imperfectly elastic and the associated energy loss is of considerable practical significance. In some applications a high energy loss is of value to provide high damping, but in many cases and particularly in tires, the temperature rise due to the losses may be a limiting operational factor. The losses cause the tire to exhibit rolling resistance which, in the case of solid tires, can be related accurately to the modulus and resilience of the rubber. An analysis of this system has been carried out by Evans, while Tabor has considered the case of rigid cylinders and spheres rolling on flexible rubber surfaces. In the case of pneumatic tires the composite nature of the construction of fabric and rubber and the complex system of strain distribution make the calculation of rolling resistance from polymer properties extremely complicated. In order to approach this problem it is necessary to know the modulus and resilience of the materials used over a very wide range of temperature and a range of amplitude of deformation and of frequency. The required temperature range may be from −60° C to above 200° C, but the frequency range over which appreciable amplitudes are involved does not extend beyond approximately a thousand cycles per second while the amplitude of deformation does not exceed 50 per cent. In order to investigate adequately the many possible combinations of polymers and compounding systems, the values of resilience and modulus are required over the above range of conditions, and various instruments have been described which measure some or all of these properties. The rebound pendulum was one of the earliest instruments and is widely used for the measurement of resilience because of its inherent simplicity of operation and high accuracy, but as normally operated at a fixed temperature does not provide sufficient information for evaluation of materials for use in tires. This type of instrument also is not well suited for determination of modulus owing to its single cycle method of operation. The vibrator type instruments give more complete information but normally demand a high degree of skill in their operation and in the interpretation of results and are more suited to research than routine work.
New Magnetic Applications in Clinical Dentistry (2005)

As new materials and technology have become available, magnetic attachment devices have become increasingly sophisticated, making them a viable option for controlling unfavorable lateral forces in the retention of removable prostheses. Various types of magnetic attachments are now available for a wide range of clinical applications. This text presents the fundamental mechanical and biologic concepts of magnetic attachments and their range of applications; introduces other magnet-related technology; and demonstrates their use in 27 clinical cases, many with long-term results.
Molecular Physiology of Bestrophins: Multifunctional Membrane Proteins Linked to Best Disease and Other Retinopathies (2008)

This article reviews the current state of knowledge about the bestrophins, a newly identified family of proteins that can function both as Cl(-) channels and as regulators of voltage-gated Ca(2+) channels. The founding member, human bestrophin-1 (hBest1), was identified as the gene responsible for a dominantly inherited, juvenile-onset form of macular degeneration called Best vitelliform macular dystrophy. Mutations in hBest1 have also been associated with a small fraction of adult-onset macular dystrophies. It is proposed that dysfunction of bestrophin results in abnormal fluid and ion transport by the retinal pigment epithelium, resulting in a weakened interface between the retinal pigment epithelium and photoreceptors. There is compelling evidence that bestrophins are Cl(-) channels, but bestrophins remain enigmatic because it is not clear that the Cl(-) channel function can explain Best disease. In addition to functioning as a Cl(-) channel, hBest1 also is able to regulate voltage-gated Ca(2+) channels. Some bestrophins are activated by increases in intracellular Ca(2+) concentration, but whether bestrophins are the molecular counterpart of Ca(2+)-activated Cl(-) channels remains in doubt. Bestrophins are also regulated by cell volume and may be a member of the volume-regulated anion channel family.
Location of Optical Fibers for the Calibration of Incoherent Optical Fiber Bundles for Image Transmission (2009)

Image transmission by incoherent optical fiber bundles (IOFBs) requires prior calibration to obtain the spatial in-out fiber correspondence to reconstruct the image captured by the pseudocamera. This information is recorded in a lookup table (LUT), which is later used for reordering the fiber positions and reconstructing the original image. This paper shows how to apply a fiber detection process to minimize the calibration time and improve the quality of the recovered image. Two different fiber detection methods were developed. The former uses the circular Hough transform algorithm based on the image gradient. The second algorithm combines a number of morphological transformations with distance transform. The results demonstrate that this technique provides a remarkable reduction in the processing time while improving fiber detection accuracy.
Enhanced Annealing of the Main Lifetime Limiting Defect in Thick 4H-SiC Layers (2008)

We have studied annealing of the main lifetime limiting defect Z1/2 in thick 4H-SiC epilayers by the application of carbon-implantation/annealing method. Examination of different implantation doses and annealing temperatures showed that finding the optimum conditions is crucial for obtaining carrier trap concentration below 1011 cm-3 in the whole 100 μm epilayer. The carrier lifetime increased from under 200 ns to over 1 μs at room temperature in the samples prepared by optimized carbon-implantation/annealing technique. Fabrication of pin diodes from the improved thick 4H-SiC epilayers confirmed the enhanced conductivity modulation and suitability of this technique for high-voltage bipolar SiC devices.
The art of false alarms in the game of deception: Leveraging fake honeypots for enhanced security (2014)

The great popularity of the Internet increases the concern for the safety of its users as many malicious Web pages pop up in daily basis. Client honeypots are tools, which are able to detect malicious Web pages, which aim to infect their visitors. These tools are widely used by researchers and anti-virus companies in their attempt to protect Internet users from being infected. Unfortunately, cyber-criminals are becoming aware of this type of detection and create evasion techniques that allow them to behave in a benign way when they feel to be threatened. This bi-faceted behavior enables them to operate for a longer period, which translates in more profit. Hence, these deceptive Web pages pose a significant challenge to existing client honeypot approaches, making them incapable to detect them when exhibit the aforementioned behavior. In this paper, we mitigate this problem by designing and developing a framework that benefits from this bi-faceted behavior. Our main goal is to protect users from being infected. More precisely, we leverage the evasion techniques used by cyber-criminals and implement a prototype, called Scarecrow, which triggers false alarms in the cases of deceptive Web pages. Consequently, the users that use Scarecrow for Web surfing can remain protected, even if they visit a malicious Website. We evaluate our implementation against malicious URLs provided by a large anti-virus company and show that when Scarecrow is deployed, malicious Websites with bi-faceted behavior do not launch their attacks against normal users.
Determination of Liquid-Vapor Equilibria (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Liquid-Vapor EquilibriaMorris. Feller and H. J. McDonaldCite this: Anal. Chem. 1950, 22, 2, 338–340Publication Date (Print):February 15, 1950Publication History Published online1 May 2002Published inissue 15 February 1950https://pubs.acs.org/doi/10.1021/ac60038a033https://doi.org/10.1021/ac60038a033research-articleACS PublicationsRequest reuse permissionsArticle Views91Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Catabolite Repression of Aox in<i>Pichia pastoris</i>Is Dependent on Hexose Transporter PpHxt1 and Pexophagy (2010)

In this work, the identification and characterization of two hexose transporter homologs in the methylotrophic yeast Pichia pastoris, P. pastoris Hxt1 (PpHxt1) and PpHxt2, are described. When expressed in a Saccharomyces cerevisiae hxt-null mutant strain that is unable to take up monosaccharides, either protein restored growth on glucose or fructose. Both PpHXT genes are transcriptionally regulated by glucose. Transcript levels of PpHXT1 are induced by high levels of glucose, whereas transcript levels of PpHXT2 are relatively lower and are fully induced by low levels of glucose. In addition, PpHxt2 plays an important role in glycolysis-dependent fermentative growth, since PpHxt2 is essential for growth on glucose or fructose when respiration is inhibited. Notably, we firstly found that the deletion of PpHXT1, but not PpHXT2, leads to the induced expression of the alcohol oxidase I gene (AOX1) in response to glucose or fructose. We also elucidated that a sharp dropping of the sugar-induced expression level of Aox at a later growth phase is caused mainly by pexophagy, a degradation pathway in methylotrophic yeast. The sugar-inducible AOX1 promoter in an Deltahxt1 strain may be promising as a host for the expression of heterologous proteins. The functional analysis of these two hexose transporters is the first step in elucidating the mechanisms of sugar metabolism and catabolite repression in P. pastoris.
Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers. (2001)

We have shown recently (B. A. Yoshida et al., Cancer Res., 59: 5483-5487) that mitogen-activated protein kinase kinase 4 (MKK4) can suppress AT6.1 rat prostate cancer metastases in vivo. Evaluation of the expression of components of the MKK4 signaling cascade showed a loss or down-regulation of expression of MKK4 or c-Jun, a downstream mediator of MKK4, in six of eight human prostate cancer cell lines. Given these findings, we next assessed whether MKK4 dysregulation occurs during the development of clinical prostate cancer. Immunohistochemical studies showed high levels of MKK4 expression in the epithelial but not the stromal compartment of normal prostatic tissues. In neoplastic tissues, a statistically significant, direct, inverse relationship between Gleason pattern and MKK4 was established. These results demonstrate that MKK4 protein is consistently down-regulated during prostate cancer progression and support a role for dysregulation of its signaling cascade in clinical disease. To test the possibility that down-regulation of MKK4 protein is the result of allelic loss, metastatic prostate cancer lesions were examined for loss of heterozygosity (LOH) within the MKK4 locus (D17S969). These studies showed a 31% (5 of 16) LOH of MKK4 that is not associated with coding region mutations, which suggests that the nucleotide sequence of the gene in the remaining allele is infrequently mutated.
Course of treatment response in first-episode and chronic schizophrenia (1996)

The results suggest that maximum symptomatic improvement occurs within the first 6 months of treatment and that disease progression may blunt treatment efficacy in both first-episode and chronic schizophrenia.
Distributed On-Chip Power Delivery (2012)

The performance of an integrated circuit depends strongly upon the power delivery system. With the introduction of ultra-small on-chip voltage regulators, novel design methodologies are needed to simultaneously determine the location of the on-chip power supplies and decoupling capacitors. In this paper, a unified design methodology is proposed to determine the optimal location of the power supplies and decoupling capacitors in high performance integrated circuits. Optimization algorithms widely used for facility location problems are applied in the proposed methodology. The effect of the number and location of the power supplies and decoupling capacitors on the power noise and response time is discussed.
Fully automatic clustering system (2002)

In this paper, the fully automatic clustering system (FACS) is presented. It is a technique for clustering and vector quantization whose objective is the automatic calculation of the codebook of the right dimension, the desired error (or target) being fixed. At each iteration, FACS tries to improve the setting of the existing codewords and, if necessary, some elements are removed from or added to the codebook. In order to save on the number of computations per iteration, greedy techniques are adopted. It has been demonstrated, from a heuristic point of view, that the number of the codewords determined by FACS is very low and that the algorithm quickly converges toward the final solution.
Effect of nicotine administration into the lateral cerebral ventricles of mice provides evidence for cholinergic mechanisms in the CNS (1976)

Numerous investigations have been carried out to elucidate cholinergic mechanisms in the central nervous system (CNS). Bhattacharya and Feldberg (1958), using perfusion of cerebral ventricles in cat, found that acetylcholine (ACh) was released into the effluent. Ryall (1963) reported that ACh is contained within synaptic endings and Curtis, Ryall and Wilkins (1965) observed the presence of ACh, cholinacetylase and cholinesterase in the CNS. Dhawan, Gupta, Dixit and Chandra (1965) showed the presence of muscarinic receptors in the CNS of dogs.