gebhart/patrepeval huggingface dataset:
Spaces of continuous functions over Dugundji compacta (2006)

We show that for every Dugundji compact $K$ of weight aleph one the Banach space $C(K)$ is 1-Plichko and the space $P(K)$ of probability measures on $K$ is Valdivia compact. Combining this result with the existence of a non-Valdivia compact group, we answer a question of Kalenda.
Egyptian Propolis: 3. Antioxidant, Antimicrobial Activities And Chemical Composition Of Propolis From Reclaimed Lands (2002)

The free radical scavenging effect of two propolis samples collected from reclaimed land, Egypt as well as of vitamin C and caffeic acid in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical system was determined. The antimicrobial (Staphylococcus aureus; Escherichia coli and Candida albicans) activity was also investigated. The results of the free radical scavenging effect of El-Saff and Ismailia propolis showed a concentration-dependent activity. The antioxidant activity was varied according to the examined material. It was obvious that caffeic acid and vitamin C showed the highest activity if compared with the propolis samples. El- Saff propolis had a higher antioxidant activity than Ismailia propolis, it showed a higher antibacterial activity against Staphylococcus aureus and a higher anti-fungal activity against Candida albicans. While the Ismailia propolis had a higher antibacterial activity against Escherichia coli, than El-Saff propolis. The chemical composition of propolis samples was investigated by GC/MS, where 75 compounds were identified, 22 being new for propolis. The Ismailia propolis was characterized by the presence of a highly significant amount of aromatic acid esters (47.3%) and triterpenoids (17.3%), while El-Saff propolis contained 3% and 1.9% respectively. The new esters belonged to 4-methoxyhydrocinnamic acid, hydroferulic acid and ferulic acid. El-Saff propolis had a very high significant amount (27%) of 2,6-bis-(pentanyloxy)-4-pentanylphenethanol, which is also a new compound for propolis.
Chromosomal abnormalities and schizophrenia (2000)

Schizophrenia is a common and serious psychiatric illness with strong evidence for genetic causation, but no specific loci yet identified. Chromosomal abnormalities associated with schizophrenia may help to understand the genetic complexity of the illness. This paper reviews the evidence for associations between chromosomal abnormalities and schizophrenia and related disorders. The results indicate that 22q11.2 microdeletions detected by fluorescence in-situ hybridization (FISH) are significantly associated with schizophrenia. Sex chromosome abnormalities seem to be increased in schizophrenia but insufficient data are available to indicate whether schizophrenia or related disorders are increased in patients with sex chromosome aneuploidies. Other reports of chromosomal abnormalities associated with schizophrenia have the potential to be important adjuncts to linkage studies in gene localization. Advances in molecular cytogenetic techniques (i.e., FISH) have produced significant increases in rates of identified abnormalities in schizophrenia, particularly in patients with very early age at onset, learning difficulties or mental retardation, or dysmorphic features. The results emphasize the importance of considering behavioral phenotypes, including adult onset psychiatric illnesses, in genetic syndromes and the need for clinicians to actively consider identifying chromosomal abnormalities and genetic syndromes in selected psychiatric patients.
Simple and Effective Load Volume Estimation in Moving Trucks using LiDARs (2019)

Industries need to track the amount of materials and goods transported through processing units in order to optimize production. In large-scale industries, trucks and trains are commonly used for transportation. The manual evaluation of the volume of material being transported by these vehicles can be imprecise, inefficient, and even unsafe for employees. Therefore, this work presents an automated system for estimating the volume of load in moving trucks using a pair of multi-layer light detection and ranging (LiDAR) sensors. The sensors are mounted in a structure so that trucks can pass through without stopping. The proposed system can be used with any type of compact load such as grains, and powders. A mesh of the load is built and used for estimating the volume. A simple, efficient, and effective heuristic is proposed for tracking the truck's positions. The system was deployed and evaluated in a mining company in real conditions of operation. Experimental results indicate that the system produces accurate estimates of the volume of ore powder transported by trucks. The reconstruction of the loads and the estimative of their volumes are performed once the data is acquired and lasts less than 1.5 minutes on average.
Understanding consistency maintenance in service discovery architectures in response to message loss (2003)

Current trends suggest future software systems will comprise collections of components that combine and recombine dynamically in reaction to changing conditions. Service-discovery protocols, which enable software components to locate available software services and to adapt to changing system topology, provide one foundation for such dynamic behavior. Emerging discovery protocols specify alternative architectures and behaviors, which motivate a rigorous investigation of the properties underlying their designs. Here, we assess the ability of selected designs for service-discovery protocols to maintain consistency in a distributed system during severe message loss. We use an architecture description language, called Rapide, to model two different architectures (two-party and three-party) and two different consistency-maintenance mechanisms (polling and notification). We use our models to investigate performance differences among combinations of architecture and consistency-maintenance mechanism as message-loss rate increases. We measure system performance along three dimensions: (1) update responsiveness (how much latency is required to propagate changes); (2) update effectiveness (what is the probability that a node receives a change?), and (3) update efficiency (how many messages must be sent to propagate a change throughout the topology?).
MOLECULAR MECHANISMS OF ANTINEOPLASTIC ACTION OF AN ANTICANCER DRUG ELLIPTICINE (2006)

Ellipticine is a potent antineoplastic agent exhibiting the multimodal mechanism of its action. This article reviews the mechanisms of predominant pharmacological and cytotoxic effects of ellipticine and shows the results of our laboratories indicating a novel mechanism of its action. The prevalent mechanisms of ellipticine antitumor, mutagenic and cytotoxic activities were suggested to be intercalation into DNA and inhibition of DNA topoisomerase II activity. We demonstrated a new mode of ellipticine action, formation of covalent DNA adducts mediated by its oxidation with cytochromes P450 (CYP) and peroxidases. The article reports the molecular mechanism of ellipticine oxidation by CYPs and identifies human and rat CYPs responsible for ellipticine metabolic activation and detoxication. It also presents a role of peroxidases (i.e. myeloperoxidase, cyclooxygenases, lactoperoxidase) in ellipticine oxidation leading to ellipticine-DNA adducts. The 9-hydroxy- and 7-hydroxyellipticine metabolites formed by CYPs and the major product of ellipticine oxidation by peroxidases, the dimer, in which the two ellipticine skeletons are connected via N(6) of the pyrrole ring of one ellipticine molecule and C9 in the second one, are the detoxication metabolites. On the contrary, 13-hydroxy- and 12-hydroxyellipticine, produced by ellipticine oxidation with CYPs, the latter one formed also spontaneously from another CYP- and peroxidase-mediated metabolite, ellipticine N(2)-oxide, are metabolites responsible for formation of two ellipticine-derived deoxyguanosine adducts in DNA. The results reviewed here allow us to propose species, two carbenium ions, ellipticine-13-ylium and ellipticine-12-ylium, as reactive species generating two major DNA adducts seen in vivo in rats treated with ellipticine. The study forms the basis to further predict the susceptibility of human cancers to ellipticine.
Transform domain channel estimation with null subcarriers for MIMO OFDM systems (2008)

International audience
Recent optical variability in LSI +61 303 (2008)

We have been monitoring the optical counterpart of the TeV emitting binary LSI +61 303 (V615 Cas) since November 2005 with the Faulkes Telescope North (on Haleakala, Maui), as part of a program to monitor long-term variability in X-ray binaries. Prompted by the recent SGR-like burst observed from a source in the region of LSI +61 303 (GCN 8209; ATel #1715; see also ATel #1731, #1740), we searched for unusual optical activity during the last two months (3rd August - 1st October).
Monophasic and biphasic stimulation evoke different responses (2003)

In 31 subjects, psychophysiological sensory perception threshold and the waveform of orthodromic sensory nerve action potentials (SNAPs) produced by constant-current 100-micros monophasic negative pulses were compared to those produced by biphasic (negative-positive) symmetrical pulses (100-micros per phase). In addition, the effects of 200-micros monophasic negative pulses were studied. Graded stimuli were delivered to the index finger, and SNAPs were recorded over the median nerve at the wrist. Perception threshold was significantly different among the three conditions. Furthermore, in 26 subjects, at the lower intensities at which SNAPs first appeared, the evoked potential waveform had two small negative phases with biphasic stimuli, but a single negative phase in response to monophasic pulses. At higher stimulus intensities, all SNAPs had a single large negative phase regardless of the stimulus. These perception and waveform findings suggest that, contrary to historical belief, the trailing positive phase of a biphasic pulse has a stimulating effect at low stimulus intensities.
“Digitally” Addressable Focusing of Light into a Subwavelength Hot Spot (2012)

We show that a plasmonic metamaterial can act as a far-field to near-field transformer that focuses a free-space beam of light into a subwavelength energy hot spot at a prescribed location with a spot size only a small fraction of the wavelength. The hot spot position on the metamaterial can be prescribed and moved at will from one metamolecule of the array to another in a "digital" fashion simply by modulating the input phase profile, thus providing new opportunities for imaging and optical data processing.
Miniaturized Dual Electromagnetic Oscillatory Actuator (2014)

In this research we propose a miniaturized dual electromagnetic oscillatory actuator. The proposed actuator is a moving magnet type voice coil actuator with two rotating parts. The structure of the actuator is simple, which includes two magnets, a coil, and a yoke. We provide a linear model for the actuator. We then determine torque and restoring constants using finite element simulation. We also present the dynamic characteristics of the actuator.
Major Plastics in Packaging (2015)

No AccessPlastics PackagingJan 2016Major Plastics in PackagingSusan E.M. Selke, John D. CulterSusan E.M. Selke, John D. Culterhttps://doi.org/10.3139/9783446437197.004SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2015Pages: 101-157Print ISBN: 978-3-446-40790-9eISBN: 978-3-446-43719-7 Copyright & Permissions© 2016 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
Device Photolithography: The Electron Beam Pattern Generator (1970)

An electron beam pattern generator is being developed to write directly on photographic plates with a 4-μm diameter beam over a 5-cm by 5-cm field with an address structure of 25,000 by 25,000. Two unique features of this pattern generator are random-access computer control of the beam and a 15-bit digital-to-analog converter stable to better than ±1 part in 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> . Capability for drawing 4-μm lines having an edge gradient less than 0.5 μm and an optical density greater than three has been demonstrated. Stability of better than ±1 μm in 24 hours over a 4-mm by 4-mm field has been achieved. Experiments still in progress have demonstrated ±1-μm stability over the entire 5-cm by 5-cm field for shorter time periods. Reticles of typical complexity are drawn routinely in less than five minutes.
Conversion of reference tapped delay line channel models to discrete time channel models [UMTS] (2003)

When simulating reference tapped delay line channel models, there is usually the problem of matching all the replica delays with simulation sampling instants. To avoid a substantial increase in simulation time, several conversion methods for obtaining channel models, with all replica delays matching sampling instants, are studied. Simulation results of a WCDMA system using RAKE receivers are shown for verifying the closeness of the results of the channel models.
Online Decision Making in VR Application Environments (2005)

The aim of this paper is to understand the process by which consumersâ perception of online VR environments impact their purchase decision. Combining factor and process models, we propose a transaction framework suggestive of consumer decision-making in VR e-commerce environments. The framework is informed by theory to be validated by an experimental design to understand the antecedents and contingencies that shape decision-making. The study contributes to research by considering a pertinent, yet parsimonious set of factors and processes that culminate in consumer decision making in rich, VR driven environments. The study contributes to practitioners by investigating how consumers perceive virtual environments that organizations are spending enormous amounts to develop and maintain, and whether consumer perceptions do impact the positive purchase decision.
Functional Evaluation of Plasmin Formation in Primary Breast Cancer (2001)

By using a zymographic assay performed directly on primary tumor tissue sections, we demonstrate that reduced tPA-mediated plasmin production is an independent adverse prognostic factor in breast cancer.
ChemInform Abstract: Total Synthesis of Epothilone B. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
eveloping a Tool Point Control Scheme for a Hydraulic Crane Using Interactive Real-time Dynamic Simulation (2010)

This paper describes the implementation of an interactive real-time dynamic simulation model of a hydraulic crane. The user input to the model is given continuously via joystick and output is presented continuously in a 3D animation. Using this simulation model, a tool point control scheme is developed for the specific crane, considering the saturation phenomena of the system and practical implementation.
Antagonist effect of chloroquine and tumor necrosis factor on hepatic oxidative stress and antioxidant defense in normal and Plasmodium yoelii nigeriensis-infected mice. (2002)

Exogenous TNF acts synergistically with P. y. nigeriensis infection to generate oxidative stress in the host and also causes an impairment of the antioxidant defense enzyme SOD, while chloroquine treatment reduces the severity of malaria infection by decreasing the blood parasitemia and also perhaps by inhibiting the TNF release.
Treatment of hypertension in the elderly (1988)

Hypertension and Cardiovascular Rehabilitation Unit, Department of Pathophysiology, University of Leuven, Leuven, Belgium
High resolution line scan interferometer for solder ball inspection using a visible supercontinuum source (2010)

A line scan interferometer, which comprises a visible supercontinuum source coupled to Fourier domain Michelson interferometer, is used to obtain 3D images of ~300 μm high solder balls on a semiconductor die with 125 nm axial and 15 μm lateral resolution. The ability to measure curved surfaces enables the determination of solder ball shape defects in addition to ball height. We show that the maximum measurable angular tilt from the sample surface normal for a given source power depends on the surface roughness of the sample. As an example, we demonstrate height measurement over +/-20 degrees from the normal on the solder balls and over +/-60 degrees on a rough steel ball bearing sample.
Regulation of X11L-dependent Amyloid Precursor Protein Metabolism by XB51, a Novel X11L-binding Protein (2000)

We isolated a cDNA encoding a novel protein, XB51, that interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L). The protein XB51 inhibited the association of X11L with amyloid precursor protein through a non-competitive mechanism and abolished the suppression of beta-amyloid production by X11L. The majority of XB51 is localized around the nucleus and recovered in 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid (CHAPS) buffer-insoluble fraction when XB51 is expressed in cells. Association of XB51 with X11L changed the intracellular distribution of XB51 and resulted in redistribution of XB51 into the CHAPS buffer-soluble fraction. These observations suggest that XB51, together with X11L, plays an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation.
Assembly of π‐Conjugated Phosphole Azahelicene Derivatives into Chiral Coordination Complexes: An Experimental and Theoretical Study (2010)

Aza[n]helicene phosphole derivatives have been prepared from aza[n]helicene diynes by the Fagan-Nugent route. Their photophysical properties (UV/Vis absorption and emission behavior) have been evaluated. Their behavior as P,N chelates towards coordination to Pd(II) and Cu(I) has been investigated: metal-bis(aza[n]helicene phosphole) assemblies are formed by a highly stereoselective coordination process, as demonstrated by X-ray crystallography. An aza[6]helicene phosphole bearing an enantiopure helicene part has been obtained, which allows the preparation of enantiopure Pd(II) and Cu(I) complexes with original topologies and high molar rotation (MR) and circular dichroism (CD). The structure-property relationship established from the experimental data has been studied in detail by theoretical studies (TDDFT calculations of UV/Vis, CD, and MR). Aza[n]helicene phosphole derivatives show pi conjugation extended over the entire molecule, and its influence on the MR of aza[6]helicene phosphole 5 c has been demonstrated. Finally, it has been shown that the nature of the metal (coordination geometry and electronic interaction) can have a great impact on the amplitude of the chiroptical properties in metal-bis(aza[n]helicene phosphole) assemblies.
Basenkatalysierte Synthese vonN-(2-Arylethyl)anilinen und basenvermittelte Dominosynthese von 2,3-Dihydroindolen (1998)

Erst die Base ermöglicht die neue Eintopfreaktion, die zu pharmazeutisch interessanten 2,3-Dihydroindolen führt. Mit Kalium-tert-butylalkoholat gelingt selektiv die Addition von primären Anilinen an substituierte Styrole und eine neue Dominoreaktion, bestehend aus einer Hydroaminierung und einer Arin-Cyclisierung (siehe Formelschema).
RB1 and p53 at the crossroad of EMT and triple-negative breast cancer (2011)

Triple-negative breast cancer (TNBC) is a heterogeneous disease that includes Basal-like and Claudin-low tumors. The Claudin-low tumors are enriched for features associated with epithelial-to-mesenchymal transition (EMT) and possibly for tumor initiating cells. Primary TNBCs respond relatively well to conventional chemotherapy; however, metastatic disease is virtually incurable. Thus, there is a great interest in identifying specific therapeutic targets for TNBC. The tumor suppressor RB1 is frequently lost in Basal-like breast cancer. To test for a causative role of RB1 gene loss in BC and for its effect on specific subtypes, we deleted mouse Rb in mammary stem/bipotent progenitor cells. This led to diverse mammary tumors including TNBC, with a subset of the latter containing p53 mutations and exhibiting features of Basal-like BC or EMT. Combined mutation of Rb and p53 in mammary stem/bipotent progenitors induced EMT type tumors. Here, we review our findings and those of others, which connect Rb and p53 to EMT in TNBC. Furthermore, we discuss how by understanding this circuit and its vulnerabilities, we may identify novel therapy for TNBC.
<i>ADAM33</i> Is Not Associated with Asthma in Puerto Rican or Mexican Populations (2003)

A recent study identified the ADAM33 gene as a promising candidate contributing to asthma. In Puerto Rican and Mexican populations, we have genotyped six single nucleotide polymorphisms (SNPs) that were used in the Genetics of Asthma in Latino Americans Study. We chose to study these two populations because in the United States, Puerto Ricans have the highest asthma prevalence, morbidity, and mortality and Mexicans the lowest. We used the transmission disequilibrium test to analyze associations between the ADAM33 gene variants and asthma, asthma severity, bronchodilator responsiveness, and total IgE levels using single SNPs, two to six SNP combinations, and specific haplotypes in 583 trios (proband with asthma and both biological parents). We also genotyped matched control samples to allow case-control analyses. None of the transmission disequilibrium test or case-control results showed significant association in either population. We found no evidence for association of single SNPs with asthma severity, bronchodilator response, or IgE levels in Mexicans or in the combined population. Two SNPs showed a modest association in Puerto Ricans, insignificant when the number of comparisons was taken into account. We conclude that the ADAM33 gene is not an important risk factor for asthma or for asthma-associated phenotypes in Mexicans or in Puerto Ricans.
Sniff nasal inspiratory pressure in patients with chronic obstructive pulmonary disease (1997)

In subjects with normal lung mechanics, inspiratory muscle strength can be reliably and easily assessed by the sniff nasal inspiratory pressure (SNIP), which is the pressure measured in an occluded nostril during a maximal sniff performed through the contralateral nostril. The aim of this study was to assess the validity of the SNIP in patients with chronic obstructive pulmonary disease (COPD), where pressure transmission from alveoli to upper airways is likely to be dampened. Twenty eight patients with COPD were studied (mean forced expiratory volume in one second (FEV1) = 36% of predicted). The SNIP and the sniff oesophageal pressure (sniff Poes) were measured simultaneously during maximal sniffs, and were compared to the maximal inspiratory pressure obtained against an occlusion (MIP). All measurements were performed from functional residual capacity in the sitting position. The ratio SNIP/sniff Poes was 0.80, and did not correlate with the degree of airflow limitation. The ratio MIP/sniff Poes was 0.87, and the ratio SNIP/MIP was 0.97. Inspiratory muscle weakness, as defined by a low sniff Poes, was present in 17 of the 28 patients. A false diagnosis of weakness was made in eight patients when MIP was considered alone, in four when SNIP was considered alone, and in only three patients when MIP and SNIP were combined. We conclude that both the sniff nasal inspiratory pressure and the maximal inspiratory pressure moderately underestimate sniff oesophageal pressure in chronic obstructive pulmonary disease. Although suboptimal in this condition, the sniff nasal inspiratory pressure appears useful to complement the maximal inspiratory pressure for assessing inspiratory muscle strength in patients with chronic obstructive pulmonary disease.