gebhart/patrepeval huggingface dataset:
Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction (2009)

Despite recent advances in the design of hemoglobin (Hb)-based oxygen carriers (HBOCs), vasoconstriction, presumably caused by nitric oxide (NO) scavenging, vessel wall hyperoxygenation, and/or extravasation, has been identified as the principal road block hampering commercial development of HBOCs. This study was designed to analyze systemic and microvascular responses to the molecular mass and plasma concentration of tense (T)-state polymerized bovine Hb (PolybHb) solutions. Experiments were performed using the hamster window chamber model subjected to successive hypervolemic infusions of T-state PolybHb solutions. PolybHb plasma concentrations were evaluated, namely, 0.5, 1.0 and 1.5 g/dl, respectively. Infusion of PolybHb solutions with molecular mass >500 kDa elicited hypertension and vasoconstriction proportional to the plasma concentration and inversely proportional to the PolybHb cross-link density. However, two high-molecular mass PolybHb solutions, PolybHb(40:1)(high) PolybHb(50:1)(high), did not elicit vasoconstriction at all concentrations studied, whereas PolybHb(50:1)(high) only elicited moderate hypertension at the highest concentration studied. In contrast, infusion of PolybHb solutions with molecular mass <500 kDa elicited significant hypertension and vasoconstriction compared with PolybHb solutions with molecular mass >500 kDa that was proportional to the plasma concentration and inversely proportional to the PolybHb cross-link density. We present promising results for highly cross-linked T-state PolybHb solutions with molecular mass >500 kDa [PolybHb(40:1)(high) PolybHb(50:1)(high)], which supports the concept that HBOC size/molecular mass influences its proximity to the vascular endothelium and molecular diffusivity. The hemodynamics of HBOC within the plasma layer surrounding the abluminal side endothelium regulates NO production and consumption, vessel oxygen flux, and extravasation. Although mechanistically attractive, neither of these hypotheses can be directly tested in vivo and will require further investigation.
Analysis of object oriented spatial access methods (1987)

This paper provides an analysis of R-trees and a variation (R+-trees) that avoids overlapping rectangles in intermediate nodes of the tree. The main contributions of the paper are the following. We provide the first known analysis of R-trees. Although formulas are given for objects in one dimension (line segments), they can be generalized for objects in higher dimensions as well. We show how the transformation of objects to higher dimensions [HINR83] can be effectively used as a tool for the analysis of R- and R+- trees. Finally, we derive formulas for R+-trees and compare the two methods analytically. The results we obtained show that R+-trees require less than half the disk accesses required by a corresponding R-tree when searching files of real life sizes R+-trees are clearly superior in cases where there are few long segments and a lot of small ones.
사회적기업가의 윤리적 리더십, 윤리적 풍토, 조직시민행동, LMX에 관한 인구통계적 차이분석 (2015)

본 연구의 목적은 사회적기업가의 인구통계학적 특성이 윤리적 리더십, 윤리적 풍토, 조직시민행동, 그리고 LMX에 미치는 영향을 탐색적으로 실증․분석함으로써 사회적기업의 지속가능경영을 위한 인적자원관리에 관한 시사점을 제시하는 데 있다. 이러한 연구 목적을 위해 국내 인증 사회적기업의 대표자 및 관리자 652명을 대상으로 실증연구를 실시하였다. 인구통계학적 특성은 성별, 종교, 이전 직장으로 구분하였다. 인구통계학적 특성에 따른 각 변수들에 관한 실증분석 결과, 첫째, 성별에 따른 윤리적 리더십의 차이가설은 부분채택 되었다. 윤리적 리더십의하위변수 중 공헌성과 정직성은 성별에 따라 다를 것이라는 가설은 채택되었으나, 분배적 공정성, 절차적공정성, 투명성은 성별에 따른 차이가 나타나지 않았다. 성별에 따른 윤리적 풍토는 하위변수 중 공리주의만 차이를 보였다. 성별에 따른 조직시민행동, LMX에 차이를 보일 것이라는 가설은 모두 기각되었다. 둘째, 종교에 따른 윤리적 리더십의 차이 가설은 부분채택 되었다. 윤리적 리더십의 하위변수 중 정직성이 종교에 따라 차이가 있을 것이라는 가설은 채택되었으며, 윤리적 풍토는 하위변수 중 공리주의만 차이를 보였다. 종교에 따른 조직시민행동은 효과성에 대하여 차이가 있는 것으로 나타났으며, 종교에 따른LMX에는 유의한 차이가 있는 것으로 나타났다. 셋째, 이전 직장에 따른 윤리적 리더십과 윤리적 풍토, 조직시민행동, LMX에 대한 차이가설은 기각되었다본 연구는 윤리적 리더십과 윤리적 풍토, 조직시민행동과 LMX의 중요성을 인식하고, 이들 변수들이 인구통계학적 변수에 따른 차이가 있음을 확인하였으며, 특히 성별과 종교 등의 개인적 특성에 따른 고려를통하여 사회적기업의 인적자원관리와 조직 관리의 발전적 방안을 도출하였다. 끝으로 본 연구의 한계와 제언을 제시하였다.
Atypical basic movement kinematics in autism spectrum conditions (2013)

Individuals with autism spectrum conditions have difficulties in understanding and responding appropriately to others. Additionally, they demonstrate impaired perception of biological motion and problems with motor control. Here we investigated whether individuals with autism move with an atypical kinematic profile, which might help to explain perceptual and motor impairments, and in principle may contribute to some of their higher level social problems. We recorded trajectory, velocity, acceleration and jerk while adult participants with autism and a matched control group conducted horizontal sinusoidal arm movements. Additionally, participants with autism took part in a biological motion perception task in which they classified observed movements as 'natural' or 'unnatural'. Results show that individuals with autism moved with atypical kinematics; they did not minimize jerk to the same extent as the matched typical control group, and moved with greater acceleration and velocity. The degree to which kinematics were atypical was correlated with a bias towards perceiving biological motion as 'unnatural' and with the severity of autism symptoms as measured by the Autism Diagnostic Observation Schedule. We suggest that fundamental differences in movement kinematics in autism might help to explain their problems with motor control. Additionally, developmental experience of their own atypical kinematic profiles may lead to disrupted perception of others' actions.
R&D on an Ultra-Thin Composite Membrane for High-Temperature Operation in PEMFC. Final Report (2003)

FuelCell Energy developed a novel high-temperature proton exchange membrane for PEM fuel cells for building applications. The laboratory PEM fuel cell successfully operated at 100-400{supdegree}C and low relative humidity to improve CO tolerance, mitigate water and thermal management challenges, and reduce membrane cost. The developed high-temperature membrane has successfully completed 500h 120C endurance testing.
디플레이션 우려와 정책대응방향 (2015)

In Korea, concerns over a arose for the first time in the summer of 2014, following three straight years of CPI falling below the target rate. Particularly, prices of agricultural crops continued to show an unusual downward trend, and the CPI fell below 1% amid stumbling oil prices in the latter half of 2014, fueling anxiety over a possible deflation. Some strongly advocated the idea of slashing the policy rate to prevent a deflation. However, according to the analysis of this report, the current deflationary concerns are overrated, and even if CPI falls below 0% for one or two quarters due to falling oil prices and agricultural crop prices, it would be a good deflation that lowers production costs as well, not a bad deflation that should be avoided at all costs by lowering the interest rates. While an interest rate cut takes substantial time to buoy the price level and the effect remains dubious, it clearly has an adverse effect of worsening household debt problems that have become the greatest threat to the Korean economy. Given this, cutting the interest rate to dispeldeflationary concernswould not be a viable option at this moment. A more direct and immediate policy response would be to lower energy-related utility prices to keep CPI in the positive territory.
Practical Near-Data Processing for In-Memory Analytics Frameworks (2015)

The end of Dennard scaling has made all systemsenergy-constrained. For data-intensive applications with limitedtemporal locality, the major energy bottleneck is data movementbetween processor chips and main memory modules. For such workloads, the best way to optimize energy is to place processing near the datain main memory. Advances in 3D integrationprovide an opportunity to implement near-data processing (NDP) withoutthe technology problems that similar efforts had in the past. This paper develops the hardware and software of an NDP architecturefor in-memory analytics frameworks, including MapReduce, graphprocessing, and deep neural networks. We develop simple but scalablehardware support for coherence, communication, and synchronization, anda runtime system that is sufficient to support analytics frameworks withcomplex data patterns while hiding all thedetails of the NDP hardware. Our NDP architecture provides up to 16x performance and energy advantageover conventional approaches, and 2.5x over recently-proposed NDP systems. We also investigate the balance between processing and memory throughput, as well as the scalability and physical and logical organization of the memory system. Finally, we show that it is critical to optimize software frameworksfor spatial locality as it leads to 2.9x efficiency improvements for NDP.
Mood, personality, and self-monitoring: Negative affect and emotionality in relation to frontal lobe mechanisms of error monitoring. (2000)

A fundamental question in frontal lobe function is how motivational and emotional parameters of behavior apply to executive processes. Recent advances in mood and personality research and the technology and methodology of brain research provide opportunities to address this question empirically. Using event-related-potentials to track error monitoring in real time, the authors demonstrated that variability in the amplitude of the error-related negativity (ERN) is dependent on mood and personality variables. College students who are high on negative affect (NA) and negative emotionality (NEM) displayed larger ERN amplitudes early in the experiment than participants who are low on these dimensions. As the high-NA and -NEM participants disengaged from the task, the amplitude of the ERN decreased. These results reveal that affective distress and associated behavioral patterns are closely related with frontal lobe executive functions.
Effects of Ultrasound, Irradiation, and Acidic Electrolyzed Water on Germination of Alfalfa and Broccoli Seeds and <i>Escherichia coli</i> O157:H7 (2006)

ABSTRACT: The ability of power ultrasound, acidic electrolyzed water (AEW), and gamma irradiation to inactivate Escherichia coli O157:H7 inoculated onto alfalfa and broccoli seeds was examined. The treatment conditions under which the alfalfa and broccoli seeds treated with sterile deionized water (SW), AEW, ultrasound cleaning tank (UST), ultrasound probe (USP), and irradiation (IR) would retain a germination percentage of >85% were first determined for each disinfection hurdle. E. coli O157:H7 inactivation tests were then conducted with the experimental conditions determined in the germination tests to find out the maximum inactivation ability of each disinfection hurdle. AEW treatment at 55 o C for 10 min reduced E. coli O157:H7 population by 3.4 and 3.3 log CFU/g for the alfalfa and broccoli seeds, respectively. IR at 8 kGy resulted in a 5‐log reduction with seed germination of >85% for both seed types, but a reduction in the length and thickness of the sprouts was observed. None of the ultrasound treatments achieved over a 2‐log reduction in E. coli O157:H7 population without lowering the germination to below 85%. The results of this study demonstrated that AEW and ultrasound, when applied individually or in combination with thermal treatment at 55 o C, were not able to deliver a satisfactory inactivation of E. coli O157:H7. A combination of several hurdles must be used to achieve a complete elimination of E. coli O157:H7 cells on alfalfa and broccoli seeds.
Chemical Constituents of Plants from the Genus Forsythia (2012)

The genus of Forsythia (Oleaceae), composing ca. 10~15 species, is mostly native to eastern Asia and used in oriental traditional medicines. Phytochemical investigations on Forsythia species have shown that triterpenoids, lignans, flavonoids, phenylethanoid glycosides and C6-C2 natural alcohols, accumulated mainly in the fruits, are the major components. Many studies have elucidated that phenolic compounds, including lignans, phenylethanoid glycosides and flavonoids are responsible for the various biological activities of the herbal medicine. This review lists 141 chemical constituents as well as their biosynthetic pathway, bioactivities and quality control as reported until September, 2011 (104 references). Keywords: Forsythia, chemical constituents, lignans, phenylethanoid glycosides, C6-C2 natural alcohols, biosynthesis, bioactivities, quality control.
Picosecond laser cutting and drilling of thin flex glass (2015)

We investigate the feasibility of cutting and drilling thin flex glass (TFG) substrates using a picosecond laser operating at wavelengths of 1030 nm, 515 nm and 343 nm. 50 μm and 100 μm thick AF32®Eco Thin Glass (Schott AG) sheets are used. The laser processing parameters such as the wavelength, pulse energy, pulse repetition frequency, scan speed and the number of laser passes which are necessary to perform through a cut or to drill a borehole in the TFG substrate are studied in detail. Our results show that the highest effective cutting speeds (220 mm/s for a 50 μm thick TFG substrate and 74 mm/s for a 100 μm thick TFG substrate) are obtained with the 1030 nm wavelength, whereas the 343 nm wavelength provides the best quality cuts. The 515 nm wavelength, meanwhile, can be used to provide relatively good laser cut quality with heat affected zones (HAZ) of <25 μm for 50 μm TFG and <40 μm for 100 μm TFG with cutting speeds of 100 mm/s and 28.5 mm/s, respectively. The 343 nm and 515 nm wavelengths can also be used for drilling micro-holes (with inlet diameters of ⩽75 µm) in the 100 μm TFG substrate with speeds of up to 2 holes per second (using 343 nm) and 8 holes per second (using 515 nm). Optical microscope and SEM images of the cuts and micro-holes are presented.
Generic Branch-Cut-and-Price (2010)

In this thesis, we present the theoretical background, implementational details and computational results concerning the generic branch-cut-and-price solver GCG.
A Retrospective on Twelve Years of LISA Proceedings (1999)

We examine two models for categorizing tasks performed by system administrators. The first model is the traditional task based model. The second model breaks tasks down by the source of the problem. We then look at the historical trends of the last 12 years of LISA proceedings based on these models. Finally, we analyze some of the more important tasks done by system administrators and propose future research in those areas. Our hope is that some of the academic rigor in analyzing research can be brought to systems administration without losing the practicality that makes the research valuable.
Chemical synthesis of 5-azacytidlne nucleotides and preparation of tRNAs containing 5-azacytidine in its 3′-terminus (1984)

5-azacytidine-5'-triphosphate prepared from 5-azacytidine by chemical phosphorylation is a substrate for AMP (CMP) tRNA nucleotidyl transferase from yeast. tRNAsPhe from yeast containing 5-azacytidine in their 3'-termini were prepared enzymatically. tRNAPhe-Cpn5CpA and tRNAPhe-n5Cpn5CpA can be aminoacylated by phenylalanyl-tRNA synthetase from yeast and they are active in the poly(U)-dependent synthesis of poly(Phe) on E. coli ribosomes. The decomposition of 5-azacytidine via hydrolysis of the triazine ring is significantly accelerated by a phosphate group on the 5'-position of the nucleotide. After the incorporation of 5-azacytidine-5'-phosphate into a polynucleotide chain the rate of hydrolysis of the triazine ring decreases considerably.
Are CD8+ dendritic cells (DC) veto cells? The role of CD8 on DC in DC development and in the regulation of CD4 and CD8 T cell responses (1997)

The CD8-expressing dendritic cells (DC) present in mouse spleen have been shown to have a regulatory effect on the CD4 and CD8 T cells they activate, restricting subsequent T cell proliferation by either inducing apoptotic T cell death (CD4 T cells) or by limiting endogenous cytokine production (CD8 T cells). To determine the role of the CD8 molecule itself in these regulatory phenomena, the DC from CD8 null mice were studied. The DC marker DEC-205 (NLDC 145) was used as a surrogate marker for CD8, since the expression of these two molecules on splenic DC was closely correlated. DC levels were normal, and the incidence of DEC-205+ and DEC-205- DC was normal in CD8 null mice, indicating that the absence of CD8 did not affect DC development. The proliferative response of T cells to allogeneic DEC-205+ DC from either CD8-/- or CD8+/+ mice was similar and was much less than the response to DEC-205- DC from these mice. This applied to both the CD4 and the CD8 T cell responses. Thus the lack of the CD8 molecule did not affect the stimulatory or regulatory properties of the DC. The regulatory CD8+ DEC-205+ DC therefore differ in that respect from antigen-presenting 'veto' cells, where CD8 itself is involved in transmitting negative signals to the T cells. DEC-205 may prove to be a more pertinent marker of the regulatory DC population.
Estimation and use of uncertainty in pseudo-relevance feedback (2007)

Existing pseudo-relevance feedback methods typically perform averaging over the top-retrieved documents, but ignore an important statistical dimension: the risk or variance associated with either the individual document models, or their combination. Treating the baseline feedback method as a black box, and the output feedback model as a random variable, we estimate a posterior distribution for the feed-back model by resampling a given query's top-retrieved documents, using the posterior mean or mode as the enhanced feedback model. We then perform model combination over several enhanced models, each based on a slightly modified query sampled from the original query. We find that resampling documents helps increase individual feedback model precision by removing noise terms, while sampling from the query improves robustness (worst-case performance) by emphasizing terms related to multiple query aspects. The result is a meta-feedback algorithm that is both more robust and more precise than the original strong baseline method.
Magnetic properties of Fe-Si thin films sputtered in mixed gas atmospheres (1989)

An examination is reported of the magnetic properties and crystal structure of films prepared by sputtering with air or oxygen added to the Ar atmosphere. The coercive force of the film deposited in air plus Ar decreased to 1/5 of that of the film deposited in pure Ar, the crystal orientation changed, and the grain size became smaller. The coercive force of the films deposited in oxygen plus Ar decreased by a like amount. The initial permeability increased accordingly. It is suggested that these changes of the magnetic properties were caused by oxidation of Si in the films.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Optical vortex beam shaping by use of highly efficient irregular spiral phase plates for optical micromanipulation (2004)

Optical dark traps such as Laguerre-Gaussian beams, modulated optical vortices, and high-order Bessel beams have been used in the micromanipulation of microparticles. Such optical traps are highly versatile, as they are able to trap both high- and low-index microparticles as well as to set them into rotation by use of the orbital angular momentum of light. Holography has been widely used to modulate the shape of an optical vortex for new optical traps. We show that, by designing the shape of a spiral phase plate and using electron-beam lithography for fabrication, one can modulate the amplitude and the phase of an optical vortex with respect to the specific shape of the spiral phase plate as required. Furthermore, to the best of our knowledge this is the first report of transferring orbital angular momentum from a spiral phase plate to an absorptive microparticle in an experiment. Hence, with this technique, optical dark traps can easily be designed and fabricated.
Enzymic saccharification of sugar beet pulp (1984)

Culture filtrates of Talaromyces emersonii UCG 208 grown on beet pulp can convert the polysaccharide components of this agricultural waste to soluble sugars. The saccharification process is facilitated if the pulp is milled or incubated with alkali or peracetic acid before addition of enzyme. However, treatment of unmilled pulp with commercial pectinase prior to incubation with Talaromyces filtrate is also very effective; under suitable conditions, complete hydrolysis of total polysaccharides has been achieved.
A video summarisation system for post-production (2003)

Post-production facilities deal with large amounts of digital video, which presents difficulties when tracking, managing and searching this material. Recent research work in image and video analysis promises to offer help in these tasks, but there is a gap between what these systems can provide and what users actually need. In particular the popular research models for indexing and retrieving visual data do not fit well with how users actually work. In this thesis we explore how image and video analysis can be applied to an online video collection to assist users in reviewing and searching for material faster, rather than purporting to do it for them.

We introduce a framework for automatically generating static 2-dimen- sional storyboards from video sequences. The storyboard consists of a series of frames, one for each shot in the sequence, showing the principal objects and motions of the shot. The storyboards are rendered as vector images in a familiar comic book style, allowing them to be quickly viewed and understood. The process consists of three distinct steps: shot-change detection, object segmentation, and presentation.

The nature of the video material encountered in a post-production fa- cility is quite different from other material such as television programmes. Video sequences such as commercials and music videos are highly dy- namic with very short shots, rapid transitions and ambiguous edits. Video is often heavily manipulated, causing difficulties for many video processing techniques.

We study the performance of a variety of published shot-change de- tection algorithms on the type of highly dynamic video typically encoun- tered in post-production work. Finding their performance disappointing, we develop a novel algorithm for detecting cuts and fades that operates directly on Motion-JPEG compressed video, exploiting the DCT coeffi- cients to save computation. The algorithm shows superior performance on highly dynamic material while performing comparably to previous algorithms on other material.
Evaluating Simultaneous Desizing and Bleaching of Greige Cotton Fabric using KMnO<sub>4</sub> (2008)

Potassium permanganate (KMnO 4 ) is used as a powerful oxidizing agent in order to make perform a simultaneous desizing and bleaching process on loomstate cotton fabrics. Experimental results demonstrate that three factors (the concentration of KMnO 4 , the treatment time and temperature) have notable impacts on the quality of bleached cotton fabric. The effects of these variables are evaluated with regards to whiteness index, tensile strength, residual size and water absorbency. At a constant oxalic acid concentration, the optimized condition is obtained in 3 g/l KMnO 4 , at 90 °C and 10 min treatment time. The results demonstrate that KMnO 4 can be accepted as a multipurpose agent for bleaching loomstate cotton fabrics and has the potential to be used as an alternative method for the simultaneous desizing and bleaching of greige cotton fabric.