gebhart/patrepeval huggingface dataset:
From program verification to program synthesis (2010)

This paper describes a novel technique for the synthesis of imperative programs. Automated program synthesis has the potential to make programming and the design of systems easier by allowing programs to be specified at a higher-level than executable code. In our approach, which we call proof-theoretic synthesis, the user provides an input-output functional specification, a description of the atomic operations in the programming language, and a specification of the synthesized program's looping structure, allowed stack space, and bound on usage of certain operations. Our technique synthesizes a program, if there exists one, that meets the input-output specification and uses only the given resources. The insight behind our approach is to interpret program synthesis as generalized program verification, which allows us to bring verification tools and techniques to program synthesis. Our synthesis algorithm works by creating a program with unknown statements, guards, inductive invariants, and ranking functions. It then generates constraints that relate the unknowns and enforces three kinds of requirements: partial correctness, loop termination, and well-formedness conditions on program guards. We formalize the requirements that program verification tools must meet to solve these constraint and use tools from prior work as our synthesizers. We demonstrate the feasibility of the proposed approach by synthesizing programs in three different domains: arithmetic, sorting, and dynamic programming. Using verification tools that we previously built in the VS3 project we are able to synthesize programs for complicated arithmetic algorithms including Strassen's matrix multiplication and Bresenham's line drawing; several sorting algorithms; and several dynamic programming algorithms. For these programs, the median time for synthesis is 14 seconds, and the ratio of synthesis to verification time ranges between 1x to 92x (with an median of 7x), illustrating the potential of the approach.
Crystallinity and the effect of ionizing radiation in polyethylene. III. An experiment on the irradiation‐induced crosslinking in <i>n</i>‐hexatriacontane (1975)

Abstract Samples of n ‐hexatriacontane irradiated in the crystalline and molten states were compared as regards the GPC chromatograms of the partially crosslinked products. From differences in the elution volumes it could be inferred that there is a greater trend for random linking along the chain in the sample irradiated in the melt as opposed to preference for end‐type linking in the samples irradiated as crystals. In the course of this work the applicability of the GPC technique for detecting short (methyl) branches and for distinguishing between the position of these branches along the chain has also become apparent.
Absence of keratan sulphate from skeletal tissues of mouse and rat (1985)

The absence of keratan sulphate synthesis from skeletal tissues of young and mature mice and rats has been confirmed by (1) analysis of specific enzyme degradation products of newly synthesized glycosaminoglycans, and (2) immunohistochemistry and radioimmunoassay using a monoclonal antibody directed against keratan sulphate. Approx. 98% of the [35S]glycosaminoglycans synthesized in vivo by mouse and rat costal cartilage, and all of those of lumbar disc, are chondroitin sulphate. The remainder in costal cartilage were identified as heparan sulphate in mature rats. In contrast, [35S]glycosaminoglycans synthesized by cornea of both species comprised both chondroitin sulphate and keratan sulphate. In mice keratan sulphate accounted for 12-25% and in rats 40-50% of the total [35S]glycosaminoglycans, depending on the age of the animal. Experiments in vitro with organ culture of cartilage and cornea confirm these results. Absence of keratan sulphate from mouse costal cartilage and lumbar disc D1-proteoglycans was corroborated by inhibition radioimmunoassay with the monoclonal antibody MZ15 and by lack of staining for keratan sulphate in indirect immunofluorescence studies using the same antibody.
A numerical-statistical approach to determining the representative elementary volume (REV) of cement paste for measuring diffusivity (2010)

Concrete diffusivity is a function of its microstructure on many scales, ranging from nanometres to millimetres. Multi-scale techniques are therefore needed to model this parameter. Representative elementary volume (REV), in conjunction with the homogenization principle, is one of the most common multi-scale approaches. This study aimed to establish a procedure for establishing the REV required to determine cement paste diffusivity based on a three-step, numerical-statistical approach. First, several series of 3D cement paste microstructures were generated with HYMOSTRUC3D, a cement hydration and microstructure model, for different volumes of cement paste and w/c ratios ranging from 0.30 to 0.60. Second, the finite element method was used to simulate the diffusion of tritiated water through these microstructures. Effective cement paste diffusivity values for different REVs were obtained by applying Fick’s law. Finally, statistical analysis was used to find the fluctuation in effective diffusivity with cement paste volume, from which the REV was then determined. The conclusion drawn was that the REV for measuring diffusivity in cement paste is 100x100x100 μm3.
D- PRODUCTION BY BACKSCATTERING FROM CLEAN ALKALI-METAL SURFACES (1977)

~dSWi!~0~2~S;nd~b;+ ~~ tNhae :~~~ range O.OS to J.S keV/nuc1eon.All measurements were made at a bllckground pressure lees than 10-9 torr and the alk.Bl1-metalsurfaces were evaporated onto a substrate in situ to assure uncontaminated surfaces.For each target, the 0-yield is at a madmum (as high as 12% per incident depteron for Cs) between 150 and JOO eV/nucleon, and !.it any measured energy, theO-yield decreases fro.m Cs to Li in the order given above.
Food safety and developing countries - the safety of the food supply has taken on a new urgency in the global marketplace (2000)

For developing countries, investment in food safety institutions and their capacity can play an important role in improving living standards through advances in domestic public health, agricultural production, and export markets. Investment is needed to establish regulatory systems and technology, build institutions, and train staff in food safety as well as in international negotiations. Approaches should facilitate the activity of the private sector and consider regional cooperation to combine resources.
Memory CD8+ T Cells Protect Dendritic Cells from CTL Killing (2008)

CD8(+) T cells have been shown to be capable of either suppressing or promoting immune responses. To reconcile these contrasting regulatory functions, we compared the ability of human effector and memory CD8(+) T cells to regulate survival and functions of dendritic cells (DC). We report that, in sharp contrast to the effector cells (CTLs) that kill DCs in a granzyme B- and perforin-dependent mechanism, memory CD8(+) T cells enhance the ability of DCs to produce IL-12 and to induce functional Th1 and CTL responses in naive CD4(+) and CD8(+) T cell populations. Moreover, memory CD8(+) T cells that release the DC-activating factor TNF-alpha before the release of cytotoxic granules induce DC expression of an endogenous granzyme B inhibitor PI-9 and protect DCs from CTL killing with similar efficacy as CD4(+) Th cells. The currently identified DC-protective function of memory CD8(+) T cells helps to explain the phenomenon of CD8(+) T cell memory, reduced dependence of recall responses on CD4(+) T cell help, and the importance of delayed administration of booster doses of vaccines for the optimal outcome of immunization.
[Detection of gamma-hydroxybutyrate (GHB) in beverages]. (2007)

After beverage samples with GHB-d6 as the internal standard were extracted with ethyl acetate, then the extracts were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA), at last the derivateized extracts analyzed by gas chromatography- mass spectrometry. After beverage samples with GHB-d6 as the internal standard were diluted by mobile phase then directly analyzed by LC/MS/MS. Results The limit of detection was 0.2 microg/mL and both relative standard deviations for between-day and within-day assays were < 8.54% in GC/MS. The limit of detection was 2 microg/mL and both relative standard deviations for between-day and within-day assays were <8.62% in LC/MS/MS. Conclusion These methods of qualitative and quantitative analysis were found to be sensitive, accurate, rapid and suitable for the forensic toxicology to test of GHB in real cases.
Analysis of c-ErbB1/Epidermal Growth Factor Receptor and c-ErbB2/HER-2 Expression in Bronchial Dysplasia: Evaluation of Potential Targets for Chemoprevention of Lung Cancer (2006)

The results suggest a prominent role for EGFR overexpression in the development and progression of bronchial dysplasia and provide rationale for exploring inhibition of EGFR signaling in lung cancer chemoprevention.
Safety of probiotic bacteria (2003)

Probiotic bacteria, by deﬁnition, are living microbial food components or inactivated microbes or parts of microbes that have a beneﬁcial effect on human health (Isolauri et al., 2002; Salminen et al., 1998). The probiotic deﬁnition requires that the efﬁcacy and safety of probiotics be veriﬁed, and thus the assessment of probiotic safety is an important part of their characterization for human use.
Fat Grafting and Stem Cell Technology (2010)

Lazar Greenfield opens his surgical text with the following: “The accelerated rate of scientific progress demands not only an expanded vocabulary but also a willingness to adopt new ideas and strategies and to readjust basic biologic concepts. Without this approach, future surgeons would be in danger of becoming surgical technicians and would fail their heritage as major contributors to medical progress.”[1]
Inflammation-Mediated Damage in Progressing Lacunar Infarctions (2002)

High concentrations of inflammatory markers in blood are associated with END and poor functional outcome in lacunar infarctions. These findings suggest that inflammation contributes to brain injury in lacunar stroke.
MetaPathways: a modular pipeline for constructing pathway/genome databases from environmental sequence information (2013)

MetaPathways provides users with a modular annotation and analysis pipeline for predicting metabolic interaction networks from environmental sequence information using an alternative to KEGG pathways and SEED subsystems mapping. It is extensible to genomic and transcriptomic datasets from a wide range of sequencing platforms, and generates useful data products for microbial community structure and function analysis. The MetaPathways software package, installation instructions, and example data can be obtained from http://hallam.microbiology.ubc.ca/MetaPathways.
Three‐dimensional growth and differentiation of ovarian tumor cell line in high aspect rotating‐wall vessel: Morphologic and embryologic considerations (1993)

Cancer of the ovary is the leading cause of death from gynecologic malignancy. To understand better these aggressive tumors, the development of in vitro models to study human ovarian cancer is critical. However, the establishment of long-term cell lines has been difficult, due to the generalized poor survival of patient tumor cells grown in primary culture. Satisfactory culture systems for ovarian tumor cells have therefore been limited. To study cellular interactions involved in the growth and differentiation of these tumors, a cell line was established from a mixed müllerian tumor of the ovary. This cell line, designated LN1, was cultured on microcarrier beads in the high aspect rotating-wall vessel. The tumor cells grown in this vessel readily proliferated without a requirement for cocultivation with a supportive cell layer. Evaluation of cellular morphology by phase contrast light microscopy and scanning electron microscopy revealed the presence of three-dimensional multicellular aggregates consisting of multiple cell-coated beads bridged together, as well as scattered aggregates of LN1 cells proliferating as spheroids free in suspension. In contrast to conventional culture systems, culture in the high aspect rotating-wall vessel facilitated the generation of multiple cell types that could be recovered. These results illustrate the ability of this culture system to provide the biological conditions necessary for pluripotent cell growth.
The Role of High Work-Function Metallic Nanodots on the Performance of a-Si:H Solar Cells: Offering Ohmic Contact to Light Trapping (2010)

Addition of carbon into p-type "window" layers in hydrogenated amorphous silicon (a-Si:H) solar cells enhances short circuit currents and open circuit voltages by a great deal. However, a-Si:H solar cells with high carbon-doped "window" layers exhibit poor fill factors due to a Schottky barrier-like impedance at the interface between a-SiC:H windows and transparent conducting oxides (TCO), although they show maximized short circuit currents and open circuit voltages. The impedance is caused by an increasing mismatch between the work function of TCO and that of p-type a-SiC:H. Applying ultrathin high-work-function metals at the interface between the two materials results in an effective lowering of the work function mismatch and a consequent ohmic behavior. If the metal layer is sufficiently thin, then it forms nanodots rather than a continuous layer which provides light-scattering effect. We demonstrate 31% efficiency enhancement by using high-work-function materials for engineering the work function at the key interfaces to raise fill factors as well as photocurrents. The use of metallic interface layers in this work is a clear contrast to previous work where attempts were made to enhance the photocurrent using plasmonic metal nanodots on the solar cell surface.
Handbook of Rocks, Minerals, and Gemstones (1993)

Contains descriptions and photographs of approximately six hundred minerals, rocks, and meteorites, providing information about the history, origin, structure, composition, properties, classification, and location of each specimen.
In situ dissolution or deposition of Ytterbium (Yb) metal in microhotplate wells for a miniaturized atomic clock (2012)

Current atomic clocks are burdened by size, weight, power and portability limitations to satisfy a broad range of potential applications. One critical need in the fabrication of a miniaturized atomic clock is small, low-power metallic sources. Exploiting the relatively high vapor pressure of ytterbium (Yb) and its dissolution in anhydrous ammonia, we report two independent techniques for depositing Yb inside a well micromachined into a microhotplate. Subsequent in situ evaporation of Yb from the microhotplate well serves as a low-power metallic source suitable for atomic clocks. The deposition and evaporation of Yb were confirmed using a variety of physicochemical techniques including quartz crystal microbalance, scanning electron microscopy, energy dispersive X-ray spectroscopy, and laser fluorescence. We also describe the fabrication of the microhotplate device, an integral component of our Yb-based miniature atomic clock. The Yb deposition/evaporation on a microhotplate well is thus useful as a low power Yb source during the fabrication of a miniaturized atomic clock, and this technique could be used for other applications requiring a vapor of a metal that has a moderate vapor pressure.
Neuronal Receptor Activity–Modifying Protein 1 Promotes Energy Expenditure in Mice (2011)

These data demonstrate that CNS RAMP1 plays a pivotal role in the regulation of energy homeostasis by promoting energy expenditure.
Role of stem-cell-derived microvesicles in the paracrine action of stem cells (2013)

The paracrine theory has recently changed the view of the biological action of stem cells and of the subsequent potential application of stem cells in regenerative medicine. Indeed, most of the beneficial effects of stem-cell-based therapy have been attributed to soluble factors released from stem cells. In this context, MVs (microvesicles) released as exosomes from the endosomal compartment, or as shedding vesicles from the cell surface, may play a relevant role in the intercellular communication between stem and injured cells. By transferring proteins, bioactive lipids, mRNA and microRNA, MVs act as vehicles of information that may lead to alteration of the phenotype of recipient cells. The exchange of information between stem cells and tissue-injured cells is reciprocal. The MV-mediated transfer of tissue-specific information from the injured cells to stem cells may reprogramme the latter to gain phenotypic and functional characteristics of the cell of origin. On the other hand, MVs released from stem cells may confer a stem-cell-like phenotype to injured cells, with the consequent activation of self-regenerative programmes. In fact, MVs released from stem cells retain several biological activities that are able to reproduce the beneficial effects of stem cells in a variety of experimental models.
Leukocytes in Diabetic Retinopathy (2007)

Diabetic retinopathy is one of the most common diabetic complications, and is a major cause of new blindness in the working-age population of developed countries. Progression of vascular abnormalities, including the selective loss of pericytes, formation of acellular capillaries, thickening of the basement membrane, and increased vascular permeability characterizes early nonproliferative diabetic retinopathy (NPDR). Capillary occlusion, as shown on fluorescein angiograms, is also one of the earliest clinically recognizable lesion of NPDR. In response to capillary non-perfusion, there is dilation of neighbouring capillaries, leading to early blood-retinal barrier breakdown, capillary non-perfusion, and endothelial cell injury and death. The resulting ischemia leads to increased production of growth factors, and the development of proliferative diabetic retinopathy (PDR), which is characterized by growth of new vessels and potential severe and irreversible visual loss. The exact pathogenic mechanism by which capillary non-perfusion occurs is still unclear but growing evidence now suggests that increased leukocyte-endothelial cell adhesion and entrapment (retinal leukostasis) in retinal capillaries is an early event associated with areas of vascular non-perfusion and the development of diabetic retinopathy. The leukocytes in diabetic patients are less deformable more activated, and demonstrate increased adhesion to the vascular endothelium. This review summarizes the current literature on the role of leukocytes in the pathogenesis of capillary occlusion, and discusses the potential of leukostasis as a new promising target in the treatment of diabetic retinopathy.
Design of an Oximeter Based on LED-LED Configuration and FPGA Technology (2013)

A fully digital photoplethysmographic (PPG) sensor and actuator has been developed. The sensing circuit uses one Light Emitting Diode (LED) for emitting light into human tissue and one LED for detecting the reflectance light from human tissue. A Field Programmable Gate Array (FPGA) is used to control the LEDs and determine the PPG and Blood Oxygen Saturation (S(p)O(2)). The configurations with two LEDs and four LEDs are developed for measuring PPG signal and Blood Oxygen Saturation (S(p)O(2)). N-LEDs configuration is proposed for multichannel S(p)O(2) measurements. The approach resulted in better spectral sensitivity, increased and adjustable resolution, reduced noise, small size, low cost and low power consumption.
An Escherichia coli dnaE mutation with suppressor activity toward mutator mutD5 (1992)

The Escherichia coli mutator mutD5 is a conditional mutator whose strength is moderate when the strain is growing in minimal medium but very strong when it is growing in rich medium. The primary defect of this strain resides in the dnaQ gene, which encodes the epsilon (exonucleolytic proofreading) subunit of the DNA polymerase III holoenzyme. In one of our mutD5 strains we discovered a mutation that suppressed the mutability of mutD5. Interestingly, the level of suppression was strong in minimal medium but weak in rich medium. The mutation was localized to the dnaE gene, which encodes the alpha (polymerase) subunit of the DNA polymerase III holoenzyme. This mutation, termed dnaE910, also conferred improved growth of the mutD5 strain and caused increased temperature sensitivity in both wild-type and dnaQ49 backgrounds. The reduction in mutator strength by dnaE910 was also observed when this allele was placed in a mutL, a mutT, or a dnaQ49 background. The results suggest that dnaE910 encodes an antimutator DNA polymerase whose effect might be mediated by improved insertion fidelity or by increased proofreading via its effect on the exonuclease activity.
How to build a faraday cage on the cheap for wireless security testing. (2005)

The commonly known security weaknesses associated with the 802.11b wireless standard have introduced a variety of security measures to countermeasure attacks. Using a wireless honeypot, a fake wireless network may be configured through emulation of devices and the TCP/IP fingerprinting of OS network stacks. TCP/IP fingerprinting is one of the most popular methods employed to determine the type of OS running on a target and this information can then be used to determine the type of vulnerabilities to target on the host. Testing the effectiveness of this technique to ensure that a wireless honeypot using honeyd may deceive an attacker has been an ongoing study due to problems conducting TCP/IP fingerprinting in the wireless environment. Research conducted in a university laboratory showed that the results were ineffective and the time taken to conduct testing could be as long as 60 hours. The subsequent exploration of different testing methods and locations illuminated on an ideal research facility called a faraday cage. The design and construction of the faraday is discussed in this paper as an affordable solution for controlled and reliable testing of TCP/IP fingerprinting against the scanning tool Network Mapper (NMAP). The results are useful when looking to deploy a deceptive honeypot as a defence mechanism against wireless attackers.
Nature of Gas Phase Mass Transfer in Gas Chromatography. (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNature of Gas Phase Mass Transfer in Gas Chromatography.J. C. GiddingsCite this: Anal. Chem. 1962, 34, 10, 1186–1192Publication Date (Print):September 1, 1962Publication History Published online1 May 2002Published inissue 1 September 1962https://doi.org/10.1021/ac60190a005RIGHTS & PERMISSIONSArticle Views141Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts