gebhart/patrepeval huggingface dataset:
PPMLT: A Pipeline Based Processing Model of Long Transactions (2011)

In web service environment, long transactions always take long time to finish, which demands the resources - often the database - to be locked for a long time. This would bring down the performance of the transaction processing system. The normal solution is compensating transaction, which creates a relative transaction with the opposite effect. When the transaction is being executed, the sub-transactions are allowed to commit independently without waiting for other sub-transactions. If the transaction fails, the respective compensating transaction will be executed to eliminate the effect brought by the original transaction. However, there are still some problems in compensating transaction model. This paper proposes a novel pipeline based processing model of long transaction (PPMLT), which parallelizes the transaction processing mainly aimed at the serially executed long transaction. This model could improve the performance the transaction processing evidently without the compensating transaction. Our experiments show that the pipeline based processing model of serial long transaction has notable improvement when executing the long transaction.
High-resolution differential mode delay measurement for a multimode optical fiber using a modified optical frequency domain reflectometer (2005)

A novel differential mode delay (DMD) measurement technique for a multimode optical fiber based on optical frequency domain reflectometry (OFDR) has been proposed. We have obtained a high-resolution DMD value of 0.054 ps/m for a commercial multimode optical fiber with length of 50 m by using a modified OFDR in a Mach-Zehnder interferometer structure with a tunable external cavity laser and a Mach-Zehnder interferometer instead of Michelson interferometer. We have also compared the OFDR measurement results with those obtained using a traditional time-domain measurement method. DMD resolution with our proposed OFDR technique is more than an order of magnitude better than a result obtainable with a conventional time-domain method.
Abstract #1233: Development of anti-Glypican 3 therapeutic antibodies (2009)

Glypican-3 is a glycosyl phosphatidylinositol-anchored protein that has been shown to be expressed in liver cancers with little expression in normal adult tissues. Loss of function mutations in Glypican-3 in humans cause Simpson-Golabi-Behmel syndrome, a disease resulting in pre and post natal overgrowth, which would seem to characterize glypican-3 more as a tumor suppressor than as an oncogene. However, our own analysis of Glypican-3 expression by Q-RT-PCR and IHC shows consistent and high expression in clinical liver cancers and cell lines such that a cytotoxic antibody targeting Glypican-3 may be a viable therapeutic in liver cancer. To this end we have generated a panel of fully human anti Glypican-3 antibodies and tested them for compatibility with anti cancer mechanisms that are independent of the function of the protein. MDX-1414 is one antibody selected from this panel, is an IgG1 isotype, and binds with high affinity and specificity to endogenously expressed Glypican-3 as seen through FACS and IHC studies. MDX-1414 is internalized on binding to HepG2 and Hep3B cell lines and can kill these cells when coupled with a saporin conjugated anti human secondary antibody (HumZAP assay). MDX-1414 can also elicit ADCC on these liver cancer cell lines. In a therapeutic xenograft model of liver cancer where HepG2 cells are allowed to grow to >100mm3 before treatment begins, MDX-1414 is able to cause significant and durable suppression of tumor growth with no evidence of any toxic side effects. Thus, Glypican-3 represents a potential target for liver cancer therapy and MDX-1414 a good candidate for the development of such a therapy where both ADCC and toxin conjugation (ADC) are viable mechanisms of action. Citation Information: In: Proc Am Assoc Cancer Res; 2009 Apr 18-22; Denver, CO. Philadelphia (PA): AACR; 2009. Abstract nr 1233.
Adaptive beacon placement (2002)

Beacon placement strongly affects the quality of spatial localization, a critical service for context-aware applications in wireless sensor networks; yet this aspect of localization has received little attention. Fixed beacon placement approaches such as uniform and very dense placement are not always viable and will be inadequate in very noisy environments in which sensor networks may be expected to operate (with high terrain and propagation uncertainties). We motivate the need for empirically adaptive beacon placement and outline a general approach based on exploration and instrumentation of the terrain conditions by a mobile human or robot agent. We design, evaluate and analyze three novel adaptive beacon placement algorithms using this approach for localization based on RF-proximity. In our evaluation, we find that beacon density rather than noise level has a more significant impact on beacon placement algorithms. Our beacon placement algorithms are applicable to a low (beacon) density regime of operation. Noise makes moderate density regimes more improvable.
Distributed Feedback Semiconductor Lasers (1998)

The book has 8 chapters that are divided into parts. The first chapter is about semiconductor-diode laser and its design. The second chapter is about gain, loss and spontaneous emissions of semiconductor lasers. The third chapter is about modelling guided waves. Fourth chapter is about optical energy exchange in guides. The fifth chapter is about basic principles of lasers with distributed feedback. Sixth chapter deals with advanced distributed feedback laser design. Seventh chapter is about numerical modelling for DFB lasers and the eighth chapter deals with future devices, modelling and systems analysis
Serum endocan role in diagnosis and prognosis of ventilator associated pneumonia (2015)

Ventilator-associated pneumonia (VAP) is a complication in as many as 28% of patients who receive mechanical ventilation. Studies have consistently shown that a delay in diagnosis and treatment increases the mortality risk. The aim of this work is to elucidate the role of the serum endocan in the diagnosis and the prognosis of ventilator associated pneumonia. Forty-two VAP patients, 20 non VAP ICU (on mechanical ventilation) admitted patients and 20 healthy control subjects of similar age and sex were included in the study. Endocan levels in serum samples were measured in all subjects. There was a highly statistically significant difference (p value <0.001) between VAP patients on one side and non VAP-ICU patients and healthy control subjects on the other side regarding the mean values of endocan. Also, the mean values of endocan were statistically significantly higher (p < 0.001) among the dead VAP group than the survivor VAP group. There was a high statistically positive correlation (p value <0.001) between mortality prediction scores (APACHE II (R = 0.549), CRIP (R = 0.599) and SOFA (R = 0.517)) and endocan serum levels. This study found increased endocan serum levels among VAP patients. We suggest a role for endocan in the diagnosis and prediction of the prognosis of VAP patients.
The New Contact Binary GSC 2414-0797 (2008)

Original article can be found at: http://www.konkoly.hu/ibvs/
On the inherent intractability of certain coding problems (Corresp.) (1978)

MEMBER, IEEE, AND HENK C. A. V~ TILBORG The fact that the general decoding problem for linear codes and the general problem of finding the weights of a linear code are both NP-complete is shown. This strongly suggests, but does not rigorously imply, that no algorithm for either of these problems which runs in polynomial time exists.
A Cheaper and More Rapid Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Method for the Detection of the HLA-H Gene Mutations Occurring in Hereditary Hemochromatosis (1997)

To the Editor :

The major histocompatibility complex class 1-like gene, HLA-H, was recently reported as being the candidate gene for the autosomal recessive disorder hereditary hemochromatosis (HH).[1][1] There is still no formal proof that HLA-H is the HH gene, but the evidence can be compelling,[
Cytomegalovirus Retinitis in Immunosuppressed Hosts (1980)

Cytomegalovirus (CMV) retinitis presents with typical ophthalmologic appearance in patients with underlying immunosuppressive conditions. Fourteen patients with this disorder were diagnosed by culture of cytomegalovirus from urine or throat specimens, elevated complement fixation titers to cytomegalovirus, and characteristic funduscopic appearance. Ten of 11 had decreased CMV-specific cell-mediated immune responses. Three of seven who received no specific therapy improved after decreasing dosages of immunosuppressive drugs. Seven patients with progressive disease despite minimal immunosuppressive therapy were treated with adenine arabinoside at doses from 1 to 20 mg/kg of body weight per day. Daily dosages of 20 mg/kg . d in five patients were associated with decreased inflammatory activity and improvement of retinal lesions and quantitative decreases in urinary virus excretion. Adenine arabinoside administration was associated with significant gastrointestinal, hematologic, and neurologic side effects. Adenine arabinoside may have some beneficial effect on selected patients with progressive CMV retinitis.
Argyria. (1987)

The distinctive blue-gray discoloration that occurs in argyria is due to deposition of silver and a silver-induced increase in melanin. Argyria is pronounced in areas of sun exposure and in the lunulae of the fingernails. Skin biopsy confirms the diagnosis by demonstrating tiny brownish granules in connective tissue surrounding sebaceous glands, in perineural tissue and in arteriolar walls. Pigmentation is permanent but benign. While the incidence of argyria is declining, its recognition remains important.
Improved NOx Storage/Release Properties of Ceria-Based Lean NOx Trap Compositions with MnOx Modification (2019)

Ceria/spinel-based lean NO<sub>x</sub> trap compositions with and without barium were modified with MnO<sub>x</sub> via incipient wetness impregnation. The effect of the MnO<sub>x</sub> layer on the aged materials (850 °C) as to the NO<sub>x</sub> storage and release properties was investigated via NO<sub>x</sub> adsorption (500 ppm NO/5% O<sub>2</sub>/balance N<sub>2</sub>) carried out at 300 °C in a dual-bed with a 1% Pt/Al<sub>2</sub>O<sub>3</sub> catalyst placed upstream of the samples to generate sufficient amounts of NO<sub>2</sub> required for efficient NO<sub>x</sub> storage. Subsequent temperature programmed desorption (TPD) experiments were carried out under N<sub>2</sub> from 300 °C to 700 °C. The addition of MnO<sub>x</sub> to the barium free composition led to a slightly reduced NO<sub>x</sub> storage capacity but all of the ad-NO<sub>x</sub> species were released from this material at significantly lower temperatures (ΔT ≈ 100 °C). The formation of a MnO<sub>x</sub> layer between ceria/spinel and barium had a remarkable effect on ageing stability as the formation of BaAl<sub>2</sub>O<sub>4</sub> was suppressed in favour of BaMnO<sub>3</sub>. The presence of this phase resulted in an increased NO<sub>x</sub> storage capacity and lower desorption temperatures. Furthermore, NO<sub>x</sub> adsorption experiments carried out in absence of the Pt-catalyst also revealed an unexpected high NO<sub>x</sub> storage ability at low NO<sub>2</sub>/NO ratios, which could make this composition suitable for various lean NO<sub>x</sub> trap catalysts (LNT) related applications.
Chemical Imaging of Self-Assembled Monolayers on Copper Using Compressive Hyperspectral Sum Frequency Generation Microscopy (2017)

Sum frequency generation microscopy is a label-free optical imaging technique with intrinsic molecular vibrational contrast for surface studies. Recent developments of compressive sensing broad-band hyperspectral SFG microscopy have demonstrated the potential application for imaging monolayer at metal surfaces with micrometer spatial resolution. Here is presented the capability of chemical imaging of spatially patterned monolayers of 1-octadecanethiol (ODT) and 16-methoxy-1-hexadecanethiol (MeOHT) molecules assembled on a copper surface. The spatial distributions of the monolayer with vibrational-spectral contrast are well-demonstrated at different frequency regions through reconstruction of the hypercube using a 3-dimensional total variation regularization algorithm (3DTV). Spatial-chemical distributions of each component are also reconstructed directly from the compressive measurements by endmember unmixing (CEU) scheme. Compared to 3DTV algorithm, the reconstruction from CEU shows spatial distribution of each component on the surfaces, and demonstrates the ability to characterize the domains of mixed-molecules on surfaces.
Fatigue in Patients With Breast Cancer Receiving Adjuvant Chemotherapy: A Review of the Literature (2002)

The aim of this literature review was to evaluate the prevalence and course of fatigue in patients with breast cancer undergoing adjuvant chemotherapy and to examine factors relating to fatigue. Fatigue is one of the most common side effects of chemotherapy. High and fluctuating prevalence rates of fatigue have been found not only during but also after adjuvant chemotherapy. The intensity of fatigue seems to be stable throughout the treatment cycles, despite the common perception that more chemotherapy treatments lead to greater fatigue. The first two days after a chemotherapy treatment seem to be the worst period. The influence of factors such as pain, impaired quality of sleep, and depression are be highly consistent across several studies, although it is often not clear whether it is the symptoms that cause the fatigue or vice versa. The outcomes of the studies indicate that several symptoms are interrelated in a network of symptoms. Factors such as changes in weight, menopausal symptoms, coping, social support, and biochemical changes have been mentioned in the literature as potentially contributing to fatigue. Results have been conflicting and need further study.
The expression of CCAAT/enhancer binding protein (C/EBP) in the human ovary in vivo: specific increase in C/EBPβ during epithelial tumour progression (1999)

The CCAAT/enhancer binding protein (C/EBP) family of transcription factors is involved in metabolism and differentiation of cells, especially in rodent liver cells and adipocytes. Their roles in vivo and in particular during pathophysiological conditions in humans are largely unknown. We have investigated the presence of C/EBPalpha, -beta, -delta and -zeta in normal ovaries and in epithelial ovarian tumours of different stages. Immunohistochemical experiments demonstrated that C/EBPalpha and C/EBPbeta were preferentially expressed in epithelial/tumour cells irrespective of stage or grade of the tumour. C/EBPbeta was located in the nuclei of the cells, in contrast to C/EBPalpha, which was present only in the cytoplasm of these cells. The nuclear localization of C/EBPbeta indicates an active role of this transcription factor in tumour cells, whereas the cytoplasmic distribution suggests a more passive function of C/EBPalpha. C/EBPdelta and -zeta demonstrated a more diverse distribution with predominant localization to epithelial cells, but stromal distribution was also noted. The intracellular distribution was confined to both the nucleus and the cytoplasm for C/EBPdelta and -zeta. Western blotting demonstrated that C/EBPalpha, -beta, -delta and -zeta were present in a majority of the samples. The amount of C/EBPbeta increased markedly with malignancy, i.e. with degree of dedifferentiation, while the other members of the C/EBP family displayed a more constant expression level. These results demonstrate an association between the expression of members of the C/EBP family and the formation of epithelial ovarian tumours, with C/EBPbeta as a potential marker for these tumours. As C/EBPbeta is known to be expressed during proliferation of cells in vitro, it may participate in the proliferative process of ovarian epithelial tumour cells in vivo and play a central role in tumour progression.
Image presentations for spinal kinematic analysis using digital videofluoroscopy (1989)

The investigation of spinal mechanics in injuries and other painful conditions is frustrated by the difficulty of measuring the kinematics between individual segments. Problems associated with current methods of measurement include the radiation dosage required, the limited accuracy obtainable and the inherent labour-intensive nature of the numerical procedures. The authors have developed a technique for overcoming these problems using digital image processing of spine motion sequences obtained from low-dose X-rays using an image intensifier. A study of the prospects for using various image processing algorithms to improve the accuracy of measurements of the kinematics of the spine from videofluoroscopic image sequences is described. >
Phosphorus speciation changes across the glass transition in highly polymerized alkali silicate glasses and melts (1996)

In situ, high-temperature Raman spectroscopy of Na,O.9SiO, glasses and melts with and without 2 mol% P,05 has been conducted to 1491 K (near the liquidus temperature). In the temperature range from 298 to ~ 1000 K (below the glass-transition temperature range), orthophosphate (PO~-) complexes appear to be the dominant phosphate species present. As temperature increases above ~ 1000 K, the orthophosphate complex is partially replaced by pyrophosphate complexes (P,Oj-) so that at ~ 1200 K >70% of the P exists in the latter form. The proportion of pyrophosphate species does not change significantly as the temperature further increases. This change in phosphate speciation is accompanied by an increase in the Q3/Q4silicate species abundance ratio. At the highest temperatures there is also evidence for Q' species in the melts. The transformation from orthophosphate to pyrophosphate implies depolymerization of the silicate network because the P/O ratio in the P,Oj complex is smaller than in PO:-. This depolymerization is consistent with the change in Q3/Q4ratio in the silicate. Therefore, use of P speciation data from glasses would lead to overestimation of the degree of polymerization of P-bearing silicate melts.
Analysis of Critical Permeabilty, Capillary Pressure and Electrical Properties for Mesaverde Tight Gas Sandstones from Western U.S. Basins (2008)

Although prediction of future natural gas supply is complicated by uncertainty in such variables as demand, liquefied natural gas supply price and availability, coalbed methane and gas shale development rate, and pipeline availability, all U.S. Energy Information Administration gas supply estimates to date have predicted that Unconventional gas sources will be the dominant source of U.S. natural gas supply for at least the next two decades (Fig. 1.1; the period of estimation). Among the Unconventional gas supply sources, Tight Gas Sandstones (TGS) will represent 50-70% of the Unconventional gas supply in this time period (Fig. 1.2). Rocky Mountain TGS are estimated to be approximately 70% of the total TGS resource base (USEIA, 2005) and the Mesaverde Group (Mesaverde) sandstones represent the principal gas productive sandstone unit in the largest Western U.S. TGS basins including the basins that are the focus of this study (Washakie, Uinta, Piceance, northern Greater Green River, Wind River, Powder River). Industry assessment of the regional gas resource, projection of future gas supply, and exploration programs require an understanding of reservoir properties and accurate tools for formation evaluation. The goal of this study is to provide petrophysical formation evaluation tools related to relative permeability, capillary pressure, electrical properties and algorithms for wireline log analysis. Detailed and accurate moveable gas-in-place resource assessment is most critical in marginal gas plays and there is need for quantitative tools for definition of limits on gas producibility due to technology and rock physics and for defining water saturation. The results of this study address fundamental questions concerning: (1) gas storage; (2) gas flow; (3) capillary pressure; (4) electrical properties; (5) facies and upscaling issues; (6) wireline log interpretation algorithms; and (7) providing a web-accessible database of advanced rock properties. The following text briefly discusses the nature of these questions. Section I.2 briefly discusses the objective of the study with respect to the problems reviewed.
Latin routers, design and implementation (1993)

An optical system in which the available bandwidth is divided into F frequency bands is considered. The connectivity of an N*N wavelength routing device, or an all-optical network with passive wavelength routing, can be specified by an N*N matrix S, where the (i, j)th element, S(i, j), is the set of wavelengths connecting input i to output j. When the matrix S is a latin square, the device is called a latin router. A class of designs for very large latin routers using a relatively small number of components is presented. The designs use a minimal number of interconnections and can be implemented distributively.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Total Chemical Synthesis of Modified Histones (2018)

In the post-genome era, epigenetics has received increasing attentions in recent years. The post-translational modifications (PTMs) of four core histones play central roles in epigenetic regulation of eukaryotic genome by either directly altering the biophysical properties of nucleosomes or by recruiting other effector proteins. In order to study the biological functions and structural mechanisms of these histone PTMs, an obligatory step is to prepare a sufficient amount of homogeneously modified histones. This task cannot be fully accomplished either by recombinant technology or enzymatic modification. In this context, synthetic chemists have developed novel protein synthetic tools and state-of-the-art chemical ligation strategies for the preparation of homologous modified histones. In this review, we summarize the recent advances in the preparation of modified histones, focusing on the total chemical synthesis strategies. The importance and potential of synthetic chemistry for the study of histone code will be also discussed.
Sensitivity and Stability of an Air-Core Fiber-Optic Gyroscope (2006)

We report an air-core fiber-optic gyroscope with similar short-term noise as a conventional gyroscope (random walk of ~0.015 deg/√hr) and a dramatically reduced sensitivity to Kerr effect (>50), temperature transients (~6.5), and Faraday effect (>10).
The effect of Chinese tea on occurrence of esophageal tumor induced by N-nitrosomethylbenzylamine in rats. (1990)

Five groups of rats (40 rats per group) were given five different varieties of Chinese tea (1 g/50 ml) and another two groups of rats (a positive control and a negative control) were given tap water as drinking water. Except for the negative control group, all the animals were intubated with N-nitrosomethylbenzylamine (NMBzA, 5 mg/kg body wt/week). Half of the animals in each group were sacrificed after 6 weeks and the remaining animals at the end of 12 weeks. The incidences of esophageal mucosa lesions (16-59%) at the end of 6 weeks were significantly lower in the tea-treated rats than in the positive control group (100%). The incidences of esophageal tumor at the end of 12 weeks (42-67%) were also significantly lower in the tea-treated groups than in the positive control group (90%). The same phenomenon was found with respect to the size and number of tumors in each tumor-bearing animal. The relative anticarcinogenic effects of the five varieties of Chinese tea were different. The Fujian oolong tea and jasmine tea exhibited the strongest effects. The results suggest that Chinese tea can effectively inhibit the carcinogenesis caused by an N-nitroso compound.