gebhart/patrepeval huggingface dataset:
A Role for Photobiomodulation in the Prevention of Myocardial Ischemic Reperfusion Injury: A Systematic Review and Potential Molecular Mechanisms (2017)

Myocardial ischemia reperfusion injury is a negative pathophysiological event that may result in cardiac cell apoptosis and is a result of coronary revascularization and cardiac intervention procedures. The resulting loss of cardiomyocyte cells and the formation of scar tissue, leads to impaired heart function, a major prognostic determinant of long-term cardiac outcomes. Photobiomodulation is a novel cardiac intervention that has displayed therapeutic effects in reducing myocardial ischemia reperfusion related myocardial injury in animal models. A growing body of evidence supporting the use of photobiomodulation in myocardial infarct models has implicated multiple molecular interactions. A systematic review was conducted to identify the strength of the evidence for the therapeutic effect of photobiomodulation and to summarise the current evidence as to its mechanisms. Photobiomodulation in animal models showed consistently positive effects over a range of wavelengths and application parameters, with reductions in total infarct size (up to 76%), decreases in inflammation and scarring, and increases in tissue repair. Multiple molecular pathways were identified, including modulation of inflammatory cytokines, signalling molecules, transcription factors, enzymes and antioxidants. Current evidence regarding the use of photobiomodulation in acute and planned cardiac intervention is at an early stage but is sufficient to inform on clinical trials.
Favorable Growth Hormone Treatment Response in a Young Boy with Achondroplasia (2016)

The growth response on GH treatment was satisfactory in the first 4 years of treatment, and the boy still continued to grow. The young age at the start of treatment was also of importance. Our other patients with achondroplasia who started treatment older had a poor response to growth hormone.
Using the web service modeling ontology to enable semantic e-business (2005)

The Web infrastructure offers businesses a way to partner and work together, integrating differing applications and communications in a seamless manner.
SUPPORT VECTOR LEARNING FOR GENDER CLASSIFICATION USING AUDIO AND VISUAL CUES (2003)

Computer vision systems for monitoring people and collecting valuable demographic information in a social environment is an important research problem. It is expected that such a system will play an increasingly important role in enhancing user's experience and can significantly improve the intelligibility of a human computer interaction (HCI) system. For example, a robust gender classification system can provide a basis for passive surveillance and access to a smart building using demographic information or can provide valuable consumer statistics in a public place. The option of an audio cue in addition to the visual cue promises a robust solution with high accuracy and ease-of-use in human computer interaction systems. This paper investigates gender classification using Support Vector Machines (SVMs). The visual (thumbnail frontal face) and the audio (features from speech data) cues were considered for designing the classifier. Three different representations of the data, namely, raw data, principle component analysis (PCA) and non-negative matrix factorization (NMF) were used for the experimentation with visual signal. For speech, mel-cepstral coefficient and pitch were used for the experimentation. It was found that the best overall classification rates obtained using the SVM for the visual and speech data were 95.31% and 100%, respectively, on data set collected in laboratory environment. The performance of the SVM was compared with two simple classifiers namely, the nearest prototype neighbor and the k-nearest neighbor on all feature sets. It was found that the SVM outperformed the other two classifiers on all datasets. To further understand the robustness issues, the proposed approach has been applied on a large balanced (roughly equal distribution of gender, ethnicity and age group) data-base consisting of 8000 faces collected in real world environment. While, the results are very promising it indicates more to be done to make a statistically meaningful conclusion.
Antisense oligonucleotide specific for transforming growth factor-beta 1 inhibit both in vitro and in vivo growth of MBT-2 murine bladder cancer. (1998)

This study demonstrates that after reducing the secretion of TGF-beta 1 on tumor cells by TGF-beta 1 antisense, ODN can inhibit their in vitro growth and in vivo tumor formation suggesting that this approach can be a potentially useful strategy to abolish the adverse immunosuppression effect of TGF-beta 1 producing autologous tumor vaccine and therefore to enhance host antitumor immune response.
Mobile access to the services in ambient networks (2008)

Ambient Networks will enable mobile terminals to communicate in an environments populated by several networks, devices, services and artefacts in a transparent way to the final user. In these scenarios, one way of implementing services uses web service architecture. So it is important to study how these mobile devices will integrate efficiently to access web services. Because of the reduced capabilities of the mobile devices, their access to web services is not easy and might have some performance costs related to show data speeds and processing both HTTP commands and XML. Moreover, sOlne mobile devices could not support web service access and if supported it lacks of web service search engine. In order to allow mobile devices to access web services efficiently, giving a solution to the previous problems, we propose a new architecture based on a peer-to-peer with distributed hash tables network, as a gateway between the mobile device and web service. This architecture is a base software simulator for an Anlbient Network environnlent developed in our research group. Nodes of the peer-topeer network publish services, allow finding them easily and acting as a gateway to the mobile devices for accessing web services more efficiently.
Topical application of TRPM8 agonists accelerates skin permeability barrier recovery and reduces epidermal proliferation induced by barrier insult: role of cold‐sensitive TRP receptors in epidermal permeability barrier homoeostasis (2010)

TRPA1 and TRPM8 receptors are activated at low temperature (A1: below 17 degrees C and M8: below 22 degrees C). Recently, we observed that low temperature (below 22 degrees C) induced elevation of intracellular calcium in keratinocytes. Moreover, we demonstrated that topical application of TRPA1 agonists accelerated the recovery of epidermal permeability barrier function after disruption. In this study, we examined the effect of topical application of TRPM8 modulators on epidermal permeability barrier homoeostasis. Immunohistochemical study and RT-PCR confirmed the expression of TRPM8 or TRPM8-like protein in epidermal keratinocytes. Topical application of TRPM8 agonists, menthol and WS 12 accelerated barrier recovery after tape stripping. The effect of WS12 was blocked by a non-selective TRP antagonist, Ruthenium Red, and a TRPM8-specific antagonist, BTCT. Topical application of WS12 also reduced epidermal proliferation associated with barrier disruption under low humidity, and this effect was blocked by BTCT. Our results indicate that TRPM8 or a closely related protein in epidermal keratinocytes plays a role in epidermal permeability barrier homoeostasis and epidermal proliferation after barrier insult.
High-power continuous-wave intracavity frequency-doubled Nd:GdVO/sub 4/-LBO laser under diode pumping into the emitting level (2005)

The continuous-wave high power laser emission of Nd:GdVO/sub 4/ at the fundamental wavelength of 1.06 /spl mu/m and its 531-nm second harmonic obtained by intracavity frequency doubling with an LBO nonlinear crystal is investigated under pumping by diode laser at 808 nm (on the /sup 4/I/sub 9/2//spl rarr//sup 4/F/sub 5/2/ transition) and 879 nm (on the /sup 4/I/sub 9/2//spl rarr//sup 4/F/sub 3/2/ transition). It is shown that, in spite of a lower absorption at 879 nm, the infrared emission is comparable under these two wavelengths of pump. The green emission performances were, however, improved by the 879 nm pump: 5.1 W at 531 nm with M/sup 2/=1.46 and 0.31 overall optical-to-optical efficiency was obtained from a 3-mm-thick 1-at.% Nd:GdVO/sub 4/ laser medium and a 10-mm-long LBO nonlinear crystal in a Z-type cavity for 16.5 W pump power. In similar conditions, the maximum green power for the 808 nm pump was 4.4 W, with 0.26 overall optical-to-optical efficiency and M/sup 2/=3.40 beam quality; at this pump wavelength the green emission shows evident saturation for pump power in excess of 9.9 W. This behavior is connected with the enhanced heat generation under 809-nm pumping, as evidenced by the increased thermal lensing of the fundamental emission. A careful alignment of the laser enables emission almost free of chaotic intensity fluctuations.
Mycotoxins in silage (2008)

Purpose of review: This paper reviews the present knowledge on mycotoxins in silage, focusing on grass and maize silage. This includes the occurrence of filamentous fungi preand postharvest, possible and confirmed mycotoxins in silage, toxicological concerns and means to prevent the problem. Findings: Preharvest contamination of grass and maize by Fusarium, Aspergillus and Alternaria can lead to contamination of silage. Well known mycotoxins deoxynivalenol (DON), zearalenone (ZEA), fumonisins and aflatoxins have been detected in silages but concentrations seldom exceed regulatory limits. It also appears that DON, ZEA and fumonisins are degraded in silage, but exact mechanisms are unknown. Postharvest spoilage is dominated by Penicillium roqueforti, Aspergillus fumigatus and Zygomycetes. Both P. roqueforti and Asp. fumigatus produce a wide range of secondary metabolites, some of them confirmed mycotoxins, others with antimicrobial or immunosuppressive effects. Some fungal metabolites have been detected in silage but many have not been looked for. Evidence for acute toxicosis caused by contaminated silage is rare. Mycotoxins in silage are more often associated with less specific symptoms like ill-thrift or decreasing yield. This may be caused by long-term exposure to the complex mixture of secondary metabolites that silage can contain. Mycotoxins with antimicrobial effects may also affect ruminant digestion. To prevent postharvest spoilage of silage the most important factor is omission of oxygen. Additives can improve certain silage properties but they are not conclusively an advantage and cannot replace good silage management. Directions for future research: The effects of long-term exposure and of complex mixtures of bioactive fungal compounds are subjects of interest. Especially high-yielding livestock may be subject to sub-acute symptoms under these conditions. There is also a need for analytical methods with specificity and accuracy to determine many of the less known mycotoxins and secondary metabolites in silage as well as possible unknown compounds.
Neural networks in J (1992)

This paper presents an attempt to implement an Artificial Neural System (ANS) in J, a significantly simplified and enhanced version of APL [1,2].Neural networks are fairly straightforward to program in a language such as J.A software tool (based on C and J) for the development and simulation of neural networks is presented in this paper.It provides a rudimentary platform for implementing ANS systems.
New and rare taxa in<i>Agaricus</i>section<i>Bivelares</i>(<i>Duploannulati</i>) (2008)

Ongoing field and laboratory studies have led to our recognition of new taxa in Agaricus section Bivelares, a recent combination and now the earliest synonym and correct name of section Duploannulati. Agaricus cupressophilus and A. tlaxcalensis, in the new Agaricus subsection Cupressorum, and A. agrinferus, A. devoniensis subsp. bridghamii, and A. subsubensis in Agaricus subsection Hortenses, are described. Agaricus subfloccosus is lectotypified. Phylogeny reconstruction methods with ITS1+2 DNA sequences were used to determine appropriate placements of the new taxa. Collectively these new taxa and phylogenetic associations represent a substantial augmentation and clarification of our knowledge of section Bivelares; described, sequenced species-level taxa in the northern hemisphere are increased from six to 10, a distinct subsectional lineage is revealed and infraspecific resolution within A. devoniensis is improved. An anomalous ITS1+2 sequence is documented in one collection of A. subsubensis. Preliminary data on another novel member of Bivelares from France also are provided. Several of these taxa are rare, highlighting opportunities and challenges for documenting biodiversity in this group. Additional comments on related taxa treated in recent publications are also provided.
Dustiness of Different High-Temperature Insulation Wools and Refractory Ceramic Fibres (2001)

Recent regulations are encouraging the replacement of older types of man-made mineral fibre by more soluble and, thus, less biopersistent compositions. In order for there to be any health benefits from this policy and to gain maximum benefit from such substitutions, the use of the new materials should not increase exposure. The work reported here was undertaken to investigate the use of new high-temperature glass insulation wools in place of refractory ceramic fibres (RCF). Airborne fibre levels occurring during the manufacture of both RCF and calcium magnesium silicate wools (CMS) were compared using measurements of genuine workplace exposure from a routine monitoring operation on the same plant. Exposures during use were compared in one customer facility where RCF and CMS blankets were used for the same task. Further comparisons were made in a laboratory test of dustiness using a "shaking box test". For some manufacturing tasks there are only a few workplace samples and there are few opportunities for genuine comparisons with both RCF and CMS in identical uses. However, both materials produced very similar exposure levels during manufacture, use and in the laboratory test. The novel magnesium silicate fibre was significantly dustier in the laboratory test.
Stability of an extemporaneously compounded levothyroxine sodium oral liquid (1996)

The stability of levothyroxine sodium in oral liquid dosage forms compounded from commercially available tablets was studied. Levothyroxine sodium oral liquids (25 micrograms/mL) were prepared from tablets and from powder with and without methylparaben preservative and transferred to amber, high-density polyethylene bottles. Five bottles of each tablet-based formulation were stored at 2-8 degrees C, 23-27 degrees C, and 38-42 degrees C, and five bottles of each powder-based formulation were stored at 38-42 degrees C. On days 3, 8, 14, 22, 31, 61, and 90, samples were taken from each bottle and analyzed for drug concentration by stability-indicating high-performance liquid chromatography. There was significant degradation of levothyroxine sodium in all the formulations. However, the tablet-based formulation without preservative stored at 4 degrees C retained at least 90% of its initial concentration for eight days after compounding. Degradation occurred faster in the tablet-based formulation with preservative. None of the formulations retained > or = 90% initial potency by day 14. An extemporaneous oral liquid formulation of levothyroxine sodium 25 micrograms/mL compounded from crushed tablets was stable for eight days when stored in amber bottles at 4 degrees C.
Sex hormones and skin collagen content in postmenopausal women. (1983)

Skin biopsy specimens were taken from 29 postmenopausal women who had not been given hormone replacement therapy and from 26 women who had been treated with oestrogen and testosterone implants for two to 10 years. The mean hydroxyproline content and therefore the mean collagen content in the skin was found to be 48% greater in the treated than the untreated women, who were matched for age. This difference was significant (p less than 0.01). The implication of this finding is that oestrogen or testosterone, or both, prevents the decrease in skin collagen content that occurs with aging and protects skin in the same way as it protects bone in postmenopausal women.
An analysis of mobile application network behavior (2016)

The impact of mobile applications in our every day lives is indisputable. While there are millions of applications available in mobile application markets, users often have very little information to rely upon when selecting which applications to download and use in terms behavior and security. Many applications may have the functionality users desire but may also have undesirable behavior such as excessive network usage, use of ads, linkage to malicious sites, or unauthorized leakage of user or application usage information. In this paper, we design a system to provide users with additional information on the application's behavior by actively eliciting and identifying undesirable behavior exhibited by mobile applications. In order to demonstrate the feasibility of our system, we use it to study the network behavior of top mobile applications listed in the Android and iOS application markets. We find that applications can be clustered into groups that have distinct behavior patterns. Using our system, users can determine an application's behavior group prior to installation on their mobile devices, reducing the exposure to any undesirable application behavior.
Smart sunglasses based on electrochromic polymers (2008)

Abstract Smart sunglasses based on electrochromic polymers are proposed and developed in this study. This article discusses the design, processing, and the optical and electrical performance of a prototype smart sunglasses based on cathodic electrochromic (EC) polymers, which show several merits compared with traditional materials for sunglasses lens as well as other smart window materials. It is a multilayer design of device. The conjugated polymer, poly[3,3‐dimethyl‐3,4‐dihydro‐2H‐thieno [3,4‐b] [1,4]dioxepine] (PProDOT‐Me 2 ), is utilized as the electrochromic working layer. The counter layer of the device is vanadium oxide (V 2 O 5 ) film, which serves as an ion storage layer. There is also a polymer gel electrolyte acting as the ionic transport layer, sandwiched between the working and counter layers. The characteristics of the prototype device are reported, including transmittance (% T ), driving power, response time, open circuit memory, and lifetime. POLYM. ENG. SCI., 2008. © 2008 Society of Plastics Engineers
Efficient allocation of radio resources for CDMA based wireless packet data systems (2003)

With the strong growth of the Internet, paralleled with the growth of mobile telephony, provision of multimedia capabilities to mobile communications becomes equivalent to the provision of fast Internet access to mobile users. Thus, third generation (3G) systems need to support high bit rates and packet data/IP access. 3G systems that provide high quality voice services as well as high speed packet data need a mechanism to share radio and network resources efficiently amongst prospective clients by utilizing the characteristics of the heterogeneous traffic. This paper is concerned with developing a "burst switching" technique as an efficient radio resource allocation scheme for a CDMA based 3G system that provides high speed packet data services. Conventional circuit and packet switching techniques become inefficient in providing wireless packet data services through CDMA due to poor resource utilization, and poor quality of service (QoS) characteristics, respectively. The proposed burst switching technique aims to overcome these problems by allocating radio resources to users for the duration of data bursts rather than an entire session or a single packet as in the case of circuit and packet switching, respectively, and releasing them at the end of the bursts for potential use by other clients. The ideal burst switching system would immediately release the physical layer resources at the beginning of the idle period following a packet burst. Its practical counterpart would make use of two timers that are used to release the physical and upper layer resources, respectively. This paper provides insights as to how these timer values should be selected to provide low delay packet service while maintaining efficient resource allocation to users.
A Hierarchical VLSM-Based Demand Response Strategy for Coordinative Voltage Control Between Transmission and Distribution Systems (2018)

This paper presents a two-stage hierarchical voltage-load sensitivity matrix (VLSM)-based demand response (DR) algorithm for regulating the voltage at distribution feeders while fulfilling the transmission system DR requests. This allows distributed energy resources to be aggregated to provide transmission-level services without causing operational issues in the distribution grids. At the beginning of each operation interval, a transmission system controller will issue DR commands to distribution system controllers. In the first stage, the distribution system controller uses a VLSM-based dispatch algorithm to dispatch the available DR resources on the distribution feeder with an objective to minimize the total voltage deviations at the lowest cost. Then, power flow studies are conducted assuming that the DR commands have been executed. If voltage violations are detected, a second-stage VLSM-based DR dispatch is performed to remove those violations. After that, the upper and lower DR limits calculated for the next operation interval are sent back to the transmission system controller so the transmission optimization algorithm can use them as operational constraints to make subsequent decisions. The DR resources include smart photovoltaic (PV) inverters that can curtail real power and provide reactive power support, controllable loads and capacitor banks. The IEEE 123-bus test system with 5-min PV and load data is used to evaluate the performance of the algorithm. Simulation results show that the proposed algorithm can fulfill the transmission-level DR requests while maintaining the voltage in the distribution system within limits.
Enhancing topological ATPG with high-level information and symbolic techniques (1998)

This paper proposes a method to enhance topological ATPG algorithms by exploiting some information computed through symbolic techniques. Since symbolic techniques can only be applied to small circuits, suitable circuit portions (named macros) are first selected, and then symbolic techniques are used to analyze their state graphs. The topological ATPG algorithm benefits from this analysis to bound its search tree. Experimental results show that the proposed approach is effective in reducing the required CPU time and increasing both the Fault Coverage and the Fault Efficiency. When high-level information about the circuit behavior and structure is available, it can be fruitfully exploited for macro selection.