gebhart/patrepeval huggingface dataset:
On the Performance of ConvNet Features for Place Recognition (2015)

After the incredible success of deep learning in the computer vision domain, there has been much interest in applying Convolutional Network (ConvNet) features in robotic fields such as visual navigation and SLAM. Unfortunately, there are fundamental differences and challenges involved. Computer vision datasets are very different in character to robotic camera data, real-time performance is essential, and performance priorities can be different. This paper comprehensively evaluates and compares the utility of three state-of-the-art ConvNets on the problems of particular relevance to navigation for robots; viewpoint-invariance and condition-invariance, and for the first time enables real-time place recognition performance using ConvNets with large maps by integrating a variety of existing (locality-sensitive hashing) and novel (semantic search space partitioning) optimization techniques. We present extensive experiments on four real world datasets cultivated to evaluate each of the specific challenges in place recognition. The results demonstrate that speed-ups of two orders of magnitude can be achieved with minimal accuracy degradation, enabling real-time performance. We confirm that networks trained for semantic place categorization also perform better at (specific) place recognition when faced with severe appearance changes and provide a reference for which networks and layers are optimal for different aspects of the place recognition problem.
An improved normalized BP based decoding algorithm for LDPC codes (2008)

A uniformly most powerful (UMP) belief propagation (BP) based algorithm is referred to as a simplified version of a BP algorithm with reduced complexity but performance loss for low density parity check (LDPC) codes. To compensate the performance loss, the normalized BP based algorithm was proposed, where the normalization factor was derived by mean ratio or by minimizing the mean square error. In this paper, an improved novel normalized BP based algorithm is proposed. The normalization uses multiplicative factor instead of divisional factor. The novel scheme shows better performance than the existing normalized BP based algorithms while keeping the same implementation complexity. The simulation is done for two kinds of LDPC codes: random constructed codes and finite geometry codes. At high signal-to-noise ratio (SNR) region, the proposed scheme can achieve even better performance than BP algorithm for short length random constructed LDPC codes.
Analgesic and anti-inflammatory effects of tranylcypromine and imipramine (1978)

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Analgesic activities of the MAO inhibitor tranylcypromine (TCP) and tricyclic antidepressant imipramine (IMP) were investigated in mice by hot plate, tail clip and bradykinin induced writhing tests. Pretreatment with TCP IO mg/kg i.p. (4h) and IMP 40 mg/kg i.p. (l/2 h) marginally raised the hot plate reaction time but markedly potentiated the morphine analgesia. They also effectively raised the reaction time in the tail clip test. In the bradykinin induced writhing test both TCP and IMP proved to be effective even in l/4 th the doses. When tested for anti-inflammatoty activities in rats TCP 2.5 mg/kg i.p. and IMP 10 mg/kg i.p. inhibited the carrageenin-induced hind paw oedema and in the same doses their daily administration for 7 days inhibited the cotton pellet granuloma.
Transgenic Models to Study Gonadotropin Function: The Role of Follicle-Stimulating Hormone in Gonadal Growth and Tumorigenesis (1999)

The role of FSH in gonadal tumorigenesis and, in particular, in human ovarian cancer has been debated. It is also unclear what role the elevated FSH levels in the inhibin-deficient mouse play in the gonadal tumorigenesis. To directly assess the role of FSH in gonadal growth, differentiation, and gonadal tumorigenesis, we have generated both gain-of-function and loss-of-function transgenic mutant mice. In the gain-of-function model, we have generated transgenic mice that ectopically overexpress human FSH from multiple tissues using a mouse metallothionein-1 promoter, achieving levels far exceeding those seen in postmenopausal women. Male transgenic mice are infertile despite normal testicular development and demonstrate enlarged seminal vesicles secondary to elevated serum testosterone levels. Female transgenic mice develop highly hemorrhagic and cystic ovaries, have elevated serum estradiol and progesterone levels, and are infertile, mimicking the features of human ovarian hyperstimulation and polycystic ovarian syndromes. Furthermore, the female transgenic mice develop enlarged and cystic kidneys and die between 6-13 weeks as a result of urinary bladder obstruction. In a complementary loss-of-function approach, we have generated double-homozygous mutant mice that lack both inhibin and FSH by a genetic intercross. In contrast to male mice lacking inhibin alone, 95% of which die of a cancer cachexia-like syndrome by 12 weeks of age, only 30% of the double-mutant male mice lacking both FSH and inhibin die by 1 yr of age. The remaining double-mutant male mice develop slow-growing and less hemorrhagic testicular tumors, which are noted after 12 weeks of age, and have minimal cachexia. Similarly, the double-mutant female mice develop slow-growing, less hemorrhagic ovarian tumors, and 70% of these mice live beyond 17 weeks. The double-mutant mice demonstrate minimal cachexia in contrast to female mice lacking only inhibin, which develop highly hemorrhagic ovarian tumors, leading to cachexia and death by 17 weeks of age in 95% of the cases. The milder cachexia-like symptoms of the inhibin and FSH double-mutant mice are correlated with low levels of serum estradiol and activin A and reduced levels of aromatase mRNA in the gonadal tumors. Based on these and our previous genetic analyses, we conclude that elevated FSH levels do not directly cause gonadal tumors. However, these results suggest FSH is an important trophic modifier factor for gonadal tumorigenesis in inhibin-deficient mice.
From monomeric to polymeric ferroelectric liquid crystals A comparative study of ferroelectric properties (1995)

Abstract Two new ferroelectric oligosiloxanes, a cyclic tetramer and a twin, have been synthesized. By a comparative study with their corresponding monomer and side chain polysiloxanes, the influence of oligo- and polymerization on the liquid crystalline and ferroelectric properties have been investigated. Polymerization leads to a stabilization of LC phases through increase of the clearing temperatures and suppression of crystallization. Oligomerization also leads to mesophase broadening, but, due to the low degree of polymerization, the effect is inferior to the linear polysiloxanes. The low viscosity of the oligosiloxanes ensures response times in the microsecond region, thus being comparable with their monomer and conventional LMWFLCs. It is found that polymerization increases the spontaneous polarization P s. This is attributed to the density increase after polymerization, enhancing the inter-mesogenic interactions. The collective and local dynamics of the OFLCs are influenced differently with respect to their molecular structures. Each oligomer is already a good model for its corresponding polymer concerning the soft mode dynamics. For the local β-relaxation a similar temperature dependence of the relaxation times τ for the cyclic tetramer and for the side chain polysiloxanes is observed. The long axial rotation of the twin, having a very efficient decoupling, is significantly faster, thus resembling the monomer.
Achieving low-cost high-reliability computation through redundant parallel processing (2006)

This paper presents a reconfigurable parallel architecture comprising an FPGA backbone and multiple processing nodes connected in a redundant array architecture and constructed mainly from low-cost commercial components. The reconfigurability of the backbone aids in allowing the system to operate as a fault-tolerant cluster utilising the principle of reliability through redundancy. Although initially designed for space-borne on-board processing of satellite imagery, the system combines the advantages of powerful computational resources with simplified software development. This makes the computer a useful general-purpose embedded processing block for critical computational tasks where fault-tolerance and high processing capabilities are required.
Characterization of Corn1 mice: Alteration of epithelial and stromal cell gene expression. (2001)

Hyperproliferative epithelial cells of corn1/corn1 mice have increased levels of expression of keratin 14 and involucrin, but do not exhibit the phenotypical characteristics of cornification. These observations indicate that factors associated with the phenotypes of corn1/corn1 mice do not alter the cornea-type epithelial differentiation of keratin 12 expression, but cause aberrant expression of lumican by corneal epithelial cells.
Ferroelectric polarization in stretched piezo- and pyroelectric poly(vinylidene fluoride-hexafluoropropylene) copolymer films (2002)

After suitable preparation, films of poly(vinylidene fluoride-hexafluoropropylene) [P(VDF-HFP)] show strong piezo- and pyroelectric effects. We investigated the polarization buildup in stretched P(VDF-HFP) copolymer films, cast from a dimethylsulfoxide/acetone solution. The films were poled under varying or constant electric fields. We observed a hysteresis of the polarization as a function of the electric field during poling of the stretched P(VDF-HFP) copolymer films with varying electric fields. From the hysteresis curve, a polarization of 24 mC/m2, and a coercive field of 100 MV/m were determined. The polarization values are lower than those of PVDF films cast from solution and stretched under the same conditions. It seems that HFP comonomer leads to a decrease in the amount of switchable dipoles. Nevertheless, the P(VDF-HFP) copolymer is very attractive because of its high piezo- and pyroelectric coefficients as well as its better chemical and thermal stability and its predicted longer lifetime. A rather uniform polarization across the whole sample thickness was found in spatially resolved measurements of the piezo- and pyroelectric properties. For comparison with PVDF and for structural information, we also report and discuss infrared transmission as well as dielectric response.
Regioselective hydrosilations. I. The hydrosilation of α,ω‐dihydrogen functional oligopolydimethylsiloxanes with 3‐vinyl‐7‐oxabicyclo[4.1.0]heptane (1993)

Abstract The hydrosilation of α,ω‐dihydrogen functional oligopolydimethylsiloxanes with epoxy compounds containing vinyl groups has been found to take place regioselectively in such a manner that compounds can be isolated in high yields in which only one SiH group has been reacted. Three different α,ω‐dihydrogen functional oligopolydimethysiloxanes with different chain lengths were monohydrosilated and the resulting epoxide monomers characterized. The rate of hydrosilation at the first SiH functional group has been shown to be considerably faster than at the second site and from these kinetic studies, activation energies for each hydrosilation step were calculated. Mechanisms are considered which offer an explantion for these observations. © 1993 John Wiley & Sons, Inc.
Induction and regulation of IL-4 receptor expression on murine macrophage cell lines and bone marrow-derived macrophages by IFN-gamma. (1990)

IL-4 is a T cell-derived cytokine that regulates the induction of proliferation of resting B cells, and appears to act on various other cells involved in the immune response. The pluripotential effects of IL-4 are dependent on the interaction of IL-4 with its receptor (IL-4R). Although the regulation and metabolism of these receptors have been examined on B and T cells, little is known about the metabolism or regulation of the IL-4R on macrophages. In studying the dynamics of IL-4R expression on the murine macrophage-like cell line J774.16, we detected the presence of low numbers of high affinity IL-4R (234 +/- 38, Kd = 110 +/- 11 pM) on the surface membrane. However, upon exposure to IFN-gamma, a potent macrophage activating cytokine, there was a rapid upregulation (within 45 min) of IL-4R (2750 +/- 178) on the cell surface, with no change in receptor affinity (Kd = 205 +/- 37 pM). Maximum expression occurred at 2 to 4 h with no further increase in IL-4R expression over the next 48 h. Cells pulsed with IFN-gamma for 45 min displayed maximum IL-4R expression by 4 h. The induction of IL-4R by IFN-gamma was dose dependent: as little as 0.5 ng/ml of IFN-gamma was capable of inducing IL-4R expression, with optimal induction at 10 ng/ml. The addition of the metabolic inhibitors actinomycin D and cycloheximide before the addition of IFN-gamma indicated that both RNA transcription and protein translation were required for this upregulation to occur.
Design, Synthesis, and Biological Evaluation of Fluoroneplanocin A as the Novel Mechanism-Based Inhibitor of <i>S</i>-Adenosylhomocysteine Hydrolase (2002)

Fluoroneplanocin A (12) was designed as a novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase (SAH) and efficiently synthesized via an electrophilic vinyl fluorination reaction (n-BuLi, N-fluorobenzenesulfonimide at -78 degrees C). Fluoroneplanocin A exhibited 2-fold more potent SAH inhibitory activity than the parent neplanocin A. A new mechanism of irreversible inhibition discovered in this work might provide new alternatives in the design of a different class of antiviral agents operating via SAH inhibition.
[POSTER] Usability Analysis of an Off-the-Shelf Hand Posture Estimation Sensor for Freehand Physical Interaction in Egocentric Mixed Reality (2017)

This paper explores freehand physical interaction in egocentric Mixed Reality by performing a usability study on the use of hand posture estimation sensors. We report on precision, interactivity and usability metrics in a task-based user study, exploring the importance of additional visual cues when interacting. A total of 750 interactions were recorded from 30 participants performing 5 different interaction tasks (Move, Rotate: Pitch (Y axis) and Yaw (Z axis), Uniform scale: enlarge and shrink). Additional visual cues resulted in an average shorter time to interact, however, no consistent statistical differences were found in between groups for performance and precision results. The group with additional visual cues gave the system and average System Usability Scale (SUS) score of 72.33 (SD 16.24) while the other scored a 68.0 (SD 18.68). Overall, additional visual cues made the system being perceived as more usable, despite the fact that the use of these two different conditions had limited effect on precision and interactivity metrics.
A Combined Transoral and Contralateral Submandibular Approach in the Surgical Management of Osteoradionecrosis of the Mandible With Free Flap Reconstruction. (2022)

We describe a method for performing mandibular resection and vascularized tissue transfer via an intraoral and contralateral submandibular approach to minimize the risk of wound complications in a radiated field. Surgery on radiated tissue associated with osteoradionecrosis of the mandible can present with oral cutaneous fistulas, dense fibrotic skin, and altered tissue planes to make dissection through this tissue tedious and can place the marginal mandibular nerve at increased risk of injury. The use of custom plates allows surgeons to minimize incisions and depend less on anatomic/visual cues during surgery to obtain an accurate result. Our experience in 8 patients has shown a predictable method for resection and reconstruction of the mandible, while minimizing the potential complications associated with previously radiated and operated patients.
Polymer Surface Processing by Atmospheric Pressure DBD for Post-Discharge Grafting of Washing-Resistant Functional Coatings (2010)

We present a process for rapid post-discharge deposition of liquid monomer to form functional coatings at atmospheric pressure. The post-discharge polymerization of dense polyacid and polyether coatings is first depicted versus the energy density deposited by the preliminary surface treatment of polyethylene and polystyrene substrates in air Dielectric Barrier Discharge (DBD) with respect to SEM, to XPS and FTIR-ATR analysis and to polymerization yield determined by mass measurements. The paper focuses on the effect of the filamentary air DBD on surface of the polymer substrates and on post-discharge polymerization mechanism. Indeed, the grafting yield is shown to depend on the energy density deposited by DBD and on the time exposure to air between DBD and monomer deposition, controlling respectively the surface density of radicals and labile peroxides, both triggering the polymerization of vinyl precursors. Then, the effect of deposition conditions on the polymerization yield and related thickness of the functional polymer coatings is shown and special attention is paid to the stability of the coating upon washing.
Detection of Amadori compounds by capillary electrophoresis coupled to tandem mass spectrometry (2004)

Capillary electrophoresis coupled to mass spectrometry (CE-MS) is reported for the first time as an alternative and powerful analytical method for the characterization and monitoring of N-substituted 1-amino-1-deoxyketoses (Amadori compounds). It allows rapid separation and identification of Amadori compounds, while benefiting from the well-known advantages of MS, such as specificity and sensitivity. Amadori compounds of several amino acids, such as glycine, valine, isoleucine, methionine, proline, and phenylalanine, as well as a cysteine-derived compound, were separated and/or discriminated using CE-MS/MS under standard conditions. The technique may also be useful to study the stability and degradation kinetics of other labile charged Maillard intermediates that play an important role in food and medical science.
Unfolded aplanats for high-concentration photovoltaics (2008)

The exigencies of high-concentration photovoltaics motivate optics that (1) obviate the need for optical bonds, (2) exhibit maximal optical tolerance, (3) are not damaged at off-axis orientation, and (4) allow convenient location of the solar cell and heat sink. We show that dual-mirror unfolded aplanats can satisfy all these criteria. Lens enhancement improves compactness and, with millimeter-scale cells, concentrator depth is only a few centimeters, amenable to precise large-volume fabrication.
The Continent Ileostomy in the Pediatric Patient (1977)

Definitive surgery for ulcerative colitis always involves removal of the target organ and construction of some sort of ileostomy. With the development of the continent intra-abdominal ileal pouch, which eliminates the need of an appliance, this reconstruction appears to be the preferred one for most patients—including children who are reliable enough and mature enough to care for their ileostomy.
Lithium ion selective electrodes based on crown ethers for serum lithium assay (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLithium ion selective electrodes based on crown ethers for serum lithium assayKeiichi. Kimura, Hideki. Oishi, Tsutomu. Miura, and Toshiyuki. ShonoCite this: Anal. Chem. 1987, 59, 19, 2331–2334Publication Date (Print):October 1, 1987Publication History Published online1 May 2002Published inissue 1 October 1987https://pubs.acs.org/doi/10.1021/ac00146a004https://doi.org/10.1021/ac00146a004research-articleACS PublicationsRequest reuse permissionsArticle Views702Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<title>Design and experimental validation of a wireless PVDF displacement sensor for structure monitoring</title> (2004)

Polyvinylidene fluoride (PVDF) is a piezoelectric polymer material. One of its most attractive applications is being used as a sensor for structure monitoring. A suitable circuit interface plays an important role in sensor design. PVDF sensor can be used in a large variety of situations according to different design of circuit. The approach to a special circuit interface, which enables PVDF sensor to be utilized as a wireless “dynamic strain gage”, is presented in this paper. The wireless PVDF sensor was then tested and all the results have been compared with strain gage output for strain and displacement measurements.
<i>Saccharomyces cerevisiae</i> Contains Two Functional Citrate Synthase Genes (1986)

The tricarboxylic acid cycle occurs within the mitochondria of the yeast Saccharomyces cerevisiae. A nuclear gene encoding the tricarboxylic acid cycle enzyme citrate synthase has previously been isolated (M. Suissa, K. Suda, and G. Schatz, EMBO J. 3:1773-1781, 1984) and is referred to here as CIT1. We report here the isolation, by an immunological method, of a second nuclear gene encoding citrate synthase (CIT2). Disruption of both genes in the yeast genome was necessary to produce classical citrate synthase-deficient phenotypes: glutamate auxotrophy and poor growth on rich medium containing lactate, a nonfermentable carbon source. Therefore, the citrate synthase produced from either gene was sufficient for these metabolic roles. Transcription of both genes was maximally repressed in medium containing both glucose and glutamate. However, transcription of CIT1 but not of CIT2 was derepressed in medium containing a nonfermentable carbon source. The significance of the presence of two genes encoding citrate synthase in S. cerevisiae is discussed.
Increased therapeutic index of weekly doxorubicin in the therapy of non-small cell lung cancer: a prospective, randomized study. (1984)

One hundred patients with non-small cell lung cancer were entered into a randomized evaluation of two schedules of doxorubicin combined with ftorafur, cyclophosphamide, and cisplatin (FACP). Doxorubicin was given either weekly at 20 mg/m2, or every three weeks (standard) at 60 mg/m2. Fifty-two patients were randomized to the FACP/weekly doxorubicin arm and 48 patients to the FACP/standard doxorubicin arm. The FACP/weekly doxorubicin regimen was associated with higher complete and partial remission rates (31% versus 19%), longer response duration (median, 33 versus 21 weeks), and longer survival duration for responders (median, 58 versus 50 weeks). These differences were not significant. Less neutropenia (p = 0.01) and less infectious morbidity (p = 0.05) were observed in the FACP/weekly doxorubicin arm. Twenty-eight patients underwent 35 endomyocardial biopsies to assess doxorubicin-induced cardiotoxicity. Sixteen biopsies were performed in 12 patients receiving cumulative doxorubicin doses ranging from 250 to 1,190 mg/m2 within the FACP/weekly doxorubicin arm. Nineteen biopsies were performed in 16 patients receiving cumulative doxorubicin doses ranging from 250 to 540 mg/m2 within the FACP/standard doxorubicin regimen. The FACP/weekly doxorubicin regimen was associated with significantly lower cardiotoxicity scores (p = 0.01). This study indicates that weekly administered doxorubicin is as effective and less cardiotoxic than the standard schedule.