gebhart/patrepeval huggingface dataset:
Design of MEMS based three-axis motion stage by incorporating a nested structure (2014)

A new design of three degrees-of-freedom (DOF) translational motion stage (XYZ stage) is presented in this paper. This XYZ stage is based on MEMS and designed by combining three existing one-DOF motion stages through a nested structure. By utilizing the previously developed stages, this approach can reduce the effort for the design and analysis steps and ensure reasonable reliability. For successful implementation, electrical connection to the engaged stages, electrical isolation among them, and additional floating frames are introduced for the chosen one-DOF motion stages. With these features, the presented XYZ stage is successfully fabricated and demonstrates the range of motion of 53.98, 49.15, and 22.91 µm along X, Y, and Z axes, respectively. The coupled motion errors among the engaged stages can be reduced to be less than 1 µm with the proposed compensation method.
Asymmetric Total Synthesis of the 1-<i>e</i><i>pi</i>-Aglycon of the Cripowellins A and B (2005)

[structure: see text] The unusual [5.3.2]-bicyclic structure of the insecticidal Amaryllidaceae alkaloids cripowellin A (1) and B (2) has been synthesized for the first time via a sequence of Sharpless dihydroxylation, ring-closing metathesis, and intramolecular Heck reaction. The asymmetric synthesis of the 1-epi-aglycon 82 proceeds with virtually complete diastereo- and enantioselectivity (de, ee > or = 98%) in 13 steps and an overall yield of 5.6%. In addition, three alternative approaches toward the aglycon 3 are also described focusing on (1) the alkylation of the 2-benzazepinedithianes 35 and 36 with the electrophile 11, (2) a radical cyclization of the precursor (R/S,S,S)-39, and (3) an intramolecular arylation reaction of the aryl ketone 47.
Aerosol‐assisted chemical vapor deposition of CeO<sub>2</sub>‐doped Y<sub>2</sub>O<sub>3</sub>‐stabilized ZrO<sub>2</sub> films on porous ceramic supports for membrane applications (1996)

Dense stabilized zirconia has a number of important applications because of its oxygen ion conductivity and excellent thermal and chemical stability. Conventional multicomponent CVD has a number of problems, including low precursor delivery rates and premature decomposition. The results in this paper suggest that the novel use of aerosol‐assisted CVD can be used to overcome these problems. The Figure shows the cross section of a CeO 2 ‐doped Y 2 O 3 ‐stabilized ZrO 2 film deposited by AACVD. magnified image
Benzamidine-based coatings: Implication of inhibitor structure on the inhibition of coagulation enzymes in solution and <i>in vitro</i> hemocompatibility assessment (2006)

Synthetic inhibitors of trypsin-like serine proteases were covalently immobilized to polymeric materials to passivate coagulation enzymes during blood contact. The inhibitory potency of a structurally simple and larger, more complex amidine derivatives was assessed against thrombin and factor Xa. After adsorption of serum albumin, the polymer films decorated with either one of the inhibitors were found to scavenge thrombin-with a higher affinity in the case of the larger inhibitor-but not factor Xa. Both inhibitor-containing coatings showed a significantly reduced thrombogenicity, coagulation activation, as well as complement activation when incubated with freshly drawn human whole blood in vitro. The authors conclude that the introduced principle offers a promising approach for hemocompatible materials for short term applications. Even rather simple inhibitors can be successfully employed for that purpose.
Vertebrate Nup53 Interacts with the Nuclear Lamina and Is Required for the Assembly of a Nup93-containing Complex (2005)

The nuclear pore complex (NPC) is an evolutionarily conserved structure that mediates exchange of macromolecules across the nuclear envelope (NE). It is comprised of approximately 30 proteins termed nucleoporins that are each present in multiple copies. We have investigated the function of the human nucleoporin Nup53, the ortholog of Saccharomyces cerevisiae Nup53p. Both cell fractionation and in vitro binding data suggest that Nup53 is tightly associated with the NE membrane and the lamina where it interacts with lamin B. We have also shown that Nup53 is capable of physically interacting with a group of nucleoporins including Nup93, Nup155, and Nup205. Consistent with this observation, depletion of Nup53 using small interfering RNAs causes a decrease in the cellular levels of these nucleoporins as well as the spindle checkpoint protein Mad1, likely due to destabilization of Nup53-containing complexes. The cellular depletion of this group of nucleoporins, induced by depleting either Nup53 or Nup93, severely alters nuclear morphology producing phenotypes similar to that previously observed in cells depleted of lamin A and Mad1. On basis of these data, we propose a model in which Nup53 is positioned near the pore membrane and the lamina where it anchors an NPC subcomplex containing Nup93, Nup155, and Nup205.
The Theory of Classical Dynamics (1985)

This textbook describes in detail the classical theory of dynamics, a subject fundamental to the physical sciences, which has a large number of important applications. The author's aim is to describe the essential content of the theory, the general way in which it is used, and the basic concepts that are involved. No deep understanding can be obtained simply by examining theoretical considerations, so Dr Griffiths has included throughout many examples and exercises. This then is an ideal textbook for an undergraduate course for physicists or mathematicians who are familiar with vector analysis.
Supporting QoS with look-ahead window contention resolution in optical burst switched networks (2004)

Optical burst switching (OBS) has been proposed as a competitive hybrid switching technology to support the next-generation optical Internet. This paper addresses the problem of contention in OBS networks and introduces a new contention resolution algorithm called look-ahead window contention resolution (LCR) that can also support service differentiation. Simulation results show that the performance of LCR is competitive to existing contention resolution mechanisms in terms of reducing burst loss.
Near-Field Antenna Arrays for Steerable Sub-Wavelength Magnetic-Field Beams (2014)

A two-dimensional array of resonant capacitively loaded loops for magnetic near-field focusing is presented. The array is designed to produce a narrow magnetic-field beam in the near-field with a reduced residual surrounding electric field. It is shown that the array allows subwavelength beam steering and shaping. The array operation is discussed and explained in detail using a simplified circuit model. The observations made based on the model are then utilized to devise an optimization procedure aimed at fine-tuning the array so as to eliminate the need in multiple excitation sources and maximize the achievable magnetic-field beam intensity. The proposed array may prove useful in a variety of applications including the improvement of wireless power transfer devices performance and the creation of efficient external sources for magnetically mediated therapy.
Automatic Contouring Of Faulted Subsurfaces (1976)

Abstract The problem of contouring a faulted surface known at randomly spaced points is analyzed and different types of solutions are proposed. The data may in fact be from a field which satisfies an elliptic partial differential equation; if the equation is harmonic, the surface corresponds to the displacement of a membrane properly raised from a horizontal plane in correspondence to the data points and cut along the faults. If the equation is biharmonic, the surface corresponds to the displacement of an elastic plate, properly riveted in correspondence to the data points and again cut along the faults. A third method analyzed, that corresponds to a family of interpolation methods, is that of two–dimensional estimation. The technique used is that of modeling the autocovariance of the data as a function of the distance between the points only. The surface will depend upon the particular function chosen and it will tend to be peaked at the data points, if the function is peaked at the origin, and smoother if the autocovariance is smoother. When faults are present, the distance between two points is defined to be the length of the shortest linking path, not cutting a fault. In the latter case, it is shown that the set of functions eligible to be chosen as autocovariances is very limited. The first method has the useful property that maxima and minima of the surface are data points. The second method generates smoother surfaces that sometimes may overshoot. Both methods are implemented by iteratively smoothing the interpolated lattice (except in the neighborhood of data points), and therefore are rather expensive in terms of computer time. The third method is not iterative and is less expensive; since the surfaces that it generates are noisy, it may be used to supply a tentative solution to be refined with an iterated smoothing. These different techniques arc discussed in detail and some examples of their application are shown.
Value proposition and social proof in online deals (2012)

In this paper, we examine the role of value proposition and social proof on the success of localized online deals that are made available in coupon form. We develop a model to understand what factors affect coupon sales of a deal and conduct an empirical validation study on Groupon.com, the leading localized daily deal website. We find that both the value proposition and the level of social proof play an important role in demand generation for deals, and that our model can successfully predict future coupon sales. Based on our findings, we describe the managerial implications and directions for future research.
The glycine cleavage system. The coupled expression of the glycine decarboxylase gene and the H-protein gene in the chicken. (1991)

Regulation of the transcription of the glycine decarboxylase gene and the H-protein gene was examined in chicken. Northern analysis suggested and run-off transcription confirmed that the glycine decarboxylase gene transcription is exclusively tissue-specific and takes place at different efficiencies in liver, kidney, and brain which are the chicken tissues exhibiting the glycine cleavage activity. No evidence for the glycine decarboxylase gene transcription was obtained in heart, spleen, and skeletal muscle. Basal and tissue-specific transcription of the H-protein gene can be distinguished. The tissue-specific transcription coordinates with transcription of the glycine decarboxylase gene in active tissues, while low abundance H-protein and its mRNA, products of the basal transcription, exist in inactive tissues together with small amounts of T-protein. Apparently, T-protein is synthesized by a process similar to that for H-protein. Glycine decarboxylase mRNA levels show a linear relationship with H-protein mRNA levels and with specific activities of the glycine cleavage reaction in active tissues. Tissue-specific distribution of the glycine cleavage activity is primarily determined by the expression of the glycine decarboxylase gene. The coordinate and tissue-specific transcription of the genes for the constituent proteins plays a key role in determining the magnitude of the glycine cleavage activity in chicken tissues and, thereby, the tissue-specificity of glycine metabolism.
Release of folic acid from sodium alginate-pectin-poly(ethylene oxide) electrospun fibers under in vitro conditions (2014)

The present study evaluated the release behavior of folic acid from ultrafine sodium alginate-pectin-poly(ethylene oxide) electrospun fibers under in vitro conditions. In aqueous solution, the release of folic acid at pH 1.2 (64%) was significantly higher than at pH 3 (21%). At pH 7.8, the majority of folic acid was released (97%) due to extensive swelling and partial dissolution of the fibers. In simulated gastric juice, the folic acid release profile was similar to that of aqueous solution at pH 1.2. By contrast, using the simulated pH 7.8 intestinal fluid, a lower amount (40%) of folic acid was released as compared with the aqueous alkaline solution. These results showed that the release of folic acid from the alginate fibers is affected by the constituents present in the simulated intestinal fluid, in addition to the pH effect. The in vitro release study showed that the composite alginate electrospun fibers have good potential as a carrier that retains folic acid in acidic food products (pH 3), but selectively releases the micronutrient in the small intestine.
Expression of the bile acid transport protein during liver development and in hepatoma cells. (1990)

The expression of the hepatocyte Na(+)-dependent bile acid transport protein during liver development and in hepatoma cells has been characterized using a monoclonal antibody (mAb 25D-1) which specifically recognizes this 49-kDa carrier system. mAb binding studies demonstrated a greatly reduced concentration of this transport protein on the surface of hepatoma tissue culture (HTC) cells, a result consistent with the greater than 95% reduction in bile acid transport capacity when compared with normal adult hepatocytes. Immunoprecipitation procedures with 25D-1 were utilized to quantitate the presence of this transport protein in HTC cells as well as in adult hepatocytes that had been labeled with [35S]methionine or Na125I. These studies indicate that the 49-kDa transport protein is not expressed either on the surface or in any intracellular compartment in HTC cells. mAb binding to fetal cells (day 17) also indicated a greatly decreased number of transport molecules in the plasma membrane. Total cell content of this carrier protein during the next 7 weeks of liver development, as measured by immunoprecipitation, increased in a linear fashion reaching 92% of the adult level at 4 weeks after birth, which parallels the increase in transport function. These results demonstrate that bile acid transport capacity is directly related to the level of expression of this 49-kDa membrane protein.
Multimedia transport in multihop wireless networks (1998)

Traditionally, multihop wireless networks focus on datagram and mobility services. The packet radio network (PRNET), for example, was a very important contribution in that it provided a conceptually simple, distributed, reliable, totally asynchronous solution to the problem. PRNET handled datagram traffic reasonably well, but did not offer efficient multimedia support. Recently, several mobile, multimedia, multihop (M3) wireless network architectures have been developed, which assume some form of synchronous, time division infrastructure. The synchronous time frame leads to efficient multimedia support implementations. However, it introduces more complexity and is less robust in the face of mobility and channel fading. The author examines the impact of synchronisation on wireless M3 network performance. First, he introduces MACA/PR, an asynchronous network based on the collision avoidance MAC scheme employed in the IEEE 802.11 standard. Then, he evaluates and compares several wireless packet networks ranging from the total asynchronous PRNET to the synchronised cluster TDMA network. He examines the tradeoffs between time synchronisation and performance in various traffic and mobility environments.
The <i>ABA1</i> gene and carotenoid biosynthesis are required for late skotomorphogenic growth in <i>Arabidopsis thaliana</i> (2007)

Several plant hormones, including auxin, brassinosteroids and gibberellins, are required for skotomorphogenesis, which is the etiolated growth that seedlings undergo in the absence of light. To examine the growth of abscisic acid (ABA)-deficient mutants in the dark, we analysed several aba1 loss-of-function alleles, which are deficient in zeaxanthin epoxidase. The aba1 mutants displayed a partially de-etiolated phenotype, including reduced hypocotyl growth, cotyledon expansion and the development of true leaves, during late skotomorphogenic growth. In contrast, only small differences in hypocotyl growth were found between wild-type seedlings and ABA-deficient mutants impaired in subsequent steps of the pathway, namely nced3, aba2, aba3 and aao3. Interestingly, phenocopies of the partially de-etiolated phenotype of the aba1 mutants were obtained when wild-type seedlings were dark-grown on medium supplemented with fluridone, an inhibitor of phytoene desaturase, and hence, of carotenoid biosynthesis. ABA supplementation did not restore the normal skotomorphogenic growth of aba1 mutants or fluridone-treated wild-type plants, suggesting a direct inhibitory effect of fluridone on carotenoid biosynthesis. In addition, aba1 mutants showed impaired production of the beta-carotene-derived xanthophylls, neoxanthin, violaxanthin and antheraxanthin. Because fluridone treatment of wild-type plants phenocopied the phenotype of dark-grown aba1 mutants, impaired carotenoid biosynthesis in aba1 mutants is probably responsible for the observed skotomorphogenic phenotype. Thus, ABA1 is required for skotomorphogenic growth, and beta-carotene-derived xanthophylls are putative regulators of skotomorphogenesis.
A 30 GS/s 4-Bit Binary Weighted DAC in SiGe BiCMOS Technology (2007)

This paper presents a 4-bit 30 GS/S binary weighted DAC in 0.25 μm BiCMOS technology. The binary weighting function was implemented in the load resistor instead of the current sources. This DAC showed 0.49 LSB and 0.57 LSB of INL and DNL respectively. 0.92 pJ FOM was achieved with 3.5V of power supply at a conversion rate of 30 GHz.
CS:APP2e Web Aside ASM:SSE: SSE-Based Support for Floating Point (2014)

The material in this document is supplementary material to the book Computer Systems, A Programmer’s Perspective, Second Edition, by Randal E. Bryant and David R. O’Hallaron, published by Prentice-Hall and copyrighted 2011. In this document, all references beginning with “CS:APP2e ” are to this book. More information about the book is available at csapp.cs.cmu.edu. This document is being made available to the public, subject to copyright provisions. You are free to copy and distribute it, but you should not use any of this material without attribution.
Useful laboratory tests for studying thrombogenesis in acute cardiac syndromes (1998)

We review laboratory tests that evaluate thrombogenesis during acute coronary syndromes. These tests have been found to be valuable research tools in more clearly understanding the pathophysiology of acute coronary syndromes. In particular, we describe tissue factor, tissue factor pathway inhibitor, prothrombin fragment 1.2, thrombin-antithrombin complex, fibrinopeptide A, tissue plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), t-PA-PAI complex, Bbeta 15-42-related peptides, fibrinogen degradation products, fibrin degradation products, D-dimer, platelet factor 4, beta-thromboglobulin, 5-hydroxytryptamine, thromboxane B2, prostacyclin, endothelin, angiotensin-converting enzyme, soluble thrombomodulin, C1-esterase inhibitor, anaphylotoxins C3a, C4a, and C5a, bradykinin, tumor necrosis factor, leukotriene C4, platelet activating factor, anti-phospholipid antibody, and von Willebrand factor. Some of these tests may prove to be useful in clinical diagnosis and management of acute coronary syndromes. Clinical outcome studies are needed to determine which tests may be cost effective and medically useful.
Insectopia (2007)

We present the pervasive game Insectopia, which have been designed by the approach of utilizing commercially available mobile phones to provide context-dependent gameplay. The design and evaluation of the game is described together with a discussion on how this approach can speed up making pervasive games a viable game genre for the general public.
Uso de la tierra en el valle de San Juan de Río, Qro (1971)

Sin resumen
THE PREPARATION AND HYDROLYSIS OF ALKYL HYDROGEN METHYLPHOSPHONATES (1965)

not available
Mimicking Isovolumic Contraction with Combined Electromechanical Stimulation Improves the Development of Engineered Cardiac Constructs (2014)

Electrical and mechanical stimulation have both been used extensively to improve the function of cardiac engineered tissue as each of these stimuli is present in the physical environment during normal development in vivo. However, to date, there has been no direct comparison between electrical and mechanical stimulation and current published data are difficult to compare due to the different systems used to create the engineered cardiac tissue and the different measures of functionality studied as outcomes. The goals of this study were twofold. First, we sought to directly compare the effects of mechanical and electrical stimulation on engineered cardiac tissue. Second, we aimed to determine the importance of the timing of the two stimuli in relation to each other in combined electromechanical stimulation. We hypothesized that delaying electrical stimulation after the beginning of mechanical stimulation to mimic the biophysical environment present during isovolumic contraction would improve construct function by improving proteins responsible for cell-cell communication and contractility. To test this hypothesis, we created a bioreactor system that would allow us to electromechanically stimulate engineered tissue created from neonatal rat cardiac cells entrapped in fibrin gel during 2 weeks in culture. Contraction force was higher for all stimulation groups as compared with the static controls, with the delayed combined stimulation constructs having the highest forces. Mechanical stimulation alone displayed increased final cell numbers but there were no other differences between electrical and mechanical stimulation alone. Delayed combined stimulation resulted in an increase in SERCA2a and troponin T expression levels, which did not happen with synchronous combined stimulation, indicating that the timing of combined stimulation is important to maximize the beneficial effect. Increases in Akt protein expression levels suggest that the improvements are at least in part induced by hypertrophic growth. In summary, combined electromechanical stimulation can create engineered cardiac tissue with improved functional properties over electrical or mechanical stimulation alone, and the timing of the combined stimulation greatly influences its effects on engineered cardiac tissue.
Ruthenium‐Catalyzed Oxidation of the Porphyrin β,β′‐Pyrrolic Ring: A General and Efficient Approach to Porpholactones (2012)

Abstract We describe an efficient ruthenium‐catalyzed oxidation of the β,β′‐pyrrolic ring on the porphyrin periphery. Through the conversion of a β,β′ ‐ double bond to a lactone moiety, the direct preparation of porpholactones from porphyrins is achieved, which previously suffered from needing toxic reagents, multiple synthetic steps and low yields. The generality of this method has been investigated with various porphyrins with different electronic and steric effects, even some metalloporphyrins, and so represents a general and efficient approach for the synthesis of the intriguing porpholactone derivatives.
II분과 : 에틸렌 처리와 저장조건에 따른 “오텀센스” 다래의 저장성및 품질특성 변화 (2014)

본 연구는 에틸렌 처리와 저장조건에 따른 ‘오텀센스’ 다래의 저장성과 품질 변화를 조사하기 위하여 수행하였다. 다래의 저장 중 품질변화를 관찰한 결과, 48시간과 96시간동안 에틸렌을 처리한 모든 처리구에서 경도는 저장기간이 경과함에 따라 급격히 감소하였으나, 당도는 급격히 증가하였다. 산도는 모든 처리구에서 0.7~1.4%수준으로 나타났다. 저장기간 동안 다래의 중량감소율을 조사한 결과, 48시간동안 에틸렌을 처리하고 저장한 다래는 저장24일 동안 20℃저장구에서 30.9%로 가장 높았으며, 2℃에 상대습도 90%저장구에서 5.9%로 가장 낮게 나타났다. 96시간동안 에틸렌을 처리하고 저장한 다래는 저장 22일 동안 20℃저장구에서 29.4%, 4℃저장구에서 20.7%, 2℃저장구에서 12.1% 그리고 2℃에 상대습도 90%저장구에서 6.0% 감소하였다. 저장기간 동안 다래의 식미는 모든 처리구에서 증가하다 감소하였다. 특히 20℃저장구는 저장 초기에 급격히 증가하다 감소하였고, 2℃에 상대습도 90%저장구는 저장 18일 후에 감소하였다. 부패율은 모든 처리구에서 저장기간 동안 증가하였으며, 20℃저장구는 저장 2일후, 2℃에 상대습도 90%저장구는 16일부터 급격히 증가하였다. 따라서, 2℃에 상대습도 90%의 저장조건이 다래의품질을 유지하는데 효과적일 것으로 판단되며, ‘오텀센스’ 다래의 적정 저장조건과 후숙시기를 판단할 수 있을 것이라 생각된다.