gebhart/patrepeval huggingface dataset:
High-Angle Gyro-While-Drilling Technology Delivers An Economical Solution To Accurate Wellbore Placement And Collision Avoidance In High-Density Multilateral Pad Drilling In The Canadian Oil Sands (2012)

Abstract Cenovus Energy initiated an aggressive infill drilling program early in 2011 in its Pelican Lake polymer/water flood project in northeast Alberta. By mid-year, the company had drilled 52 injection and producing wells, and drilling is scheduled to continue at the same pace through year-end. Pelican Lake employs a two-phase drilling program from 18-well pads: batch-drilling the intermediate hole sections to approximately 425m MD at 70° of inclination; using follow-up rigs to drill the horizontal sections of over 2,000m in the Wabiskaw formation. Wellbore collisions in the intermediate phase and landing the wells accurately prior to horizontal drilling are critical concerns. Highly accurate gyroscopic surveying techniques are required throughout the project considering the close well spacing and congestion of existing wells. Early in 2011, the company tested a new gyro-while-drilling (GWD) system, capable of accurate performance up to 70° of inclination versus the 20° to 40° of previous models. If successful, the higher operational range would facilitate collision avoidance and accurate well placement in one operation with real-time data, potentially enhancing both the economics and the feasibility of the drilling program. Since accurate well placement was so critical—some well passes would be as close as 4 meters—the company developed a plan to evaluate the new tool: first, by surveying previously surveyed wells and comparing the results; and, second, by running back-up gyro surveys on wireline during drilling. GWD performance exceeded expectations, both in the initial tests and in the drilling operations—to the extent that the back-up surveys were eliminated, with the GWD data accepted as the definitive wellbore survey. This paper will provide the results of the initial tests and analyze GWD performance during drilling with statistics compiled from 36 wells. The savings from eliminating the back-up surveys will be presented along with other benefits and observations.
Vessel Tracking in Peripheral CTA Datasets -- An Overview (2001)

In this paper, we describe the results of the literature re-viewfocused on the peripheral vessel segmentation in 3Dmedical datasets, acquired by Computer tomography angiography(CTA) of the human leg.The fundamental aim of such a segmentation task is arobust method for the detection of main vessels in the legthat simultaneously preserves the vessel calcification (thesediment is called plaque) and allows localization of vesselnarrowings (called stenoses). This segmentation has to befree from artifacts, i.e., without false detections of stenosesand without false omitting of any stenotic part. The papercollects seven methods applicable for vessel segmentation.
<i>In Vitro</i> Recombinants of Antibiotic-Resistant Chlamydia trachomatis Strains Have Statistically More Breakpoints than Clinical Recombinants for the Same Sequenced Loci and Exhibit Selection at Unexpected Loci (2011)

Lateral gene transfer (LGT) is essential for generating between-strain genomic recombinants of Chlamydia trachomatis to facilitate the organism's evolution. Because there is no reliable laboratory-based gene transfer system for C. trachomatis, in vitro generation of recombinants from antibiotic-resistant strains is being used to study LGT. However, selection pressures imposed on in vitro recombinants likely affect statistical properties of recombination relative to naturally occurring clinical recombinants, including prevalence at particular loci. We examined multiple loci for 16 in vitro-derived recombinants of ofloxacin- and rifampin-resistant L(1) and D strains, respectively, grown with both antibiotics, and compared these with the same sequenced loci among 11 clinical recombinants. Breakpoints and recombination frequency were examined using phylogenetics, bioinformatics, and statistics. In vitro and clinical isolates clustered perfectly into two groups, without misclassification, using Ward's minimum variance based on breakpoint data. As expected, gyrA (confers ofloxacin resistance) and rpoB (confers rifampin resistance) had significantly more breakpoints among in vitro recombinants than among clinical recombinants (P < 0.0001 and P = 0.02, respectively, using the Wilcoxon rank sum test). Unexpectedly, trpA also had significantly more breakpoints for in vitro recombinants (P < 0.0001). There was also significant selection at other loci. The strongest bias was for ompA in strain D (P = 3.3 × 10(-8)). Our results indicate that the in vitro model differs statistically from natural recombination events. Additional genomic studies are needed to determine the factors responsible for the observed selection biases at unexpected loci and whether these are important for LGT to inform approaches for genetically manipulating C. trachomatis.
The Changing Face of Audio-Media in India During Post Privatization Period:An Empirical Study (2009)

Privatization is the key word after liberalization. Every sector has tasted the success of privatization; broadcasting media is not an exception. The changing face of audio-media after privatization has been studied in this article. The study considers the different factors which are popularizing the audio-media among the respondents, contribution of FM channels towards teaching and social welfare, attitudinal change of the listeners, attitudinal change of business houses etc. The period of study is from 2007-2008.
Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice, With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia (2012)

In older patients with AML, decitabine improved response rates compared with standard therapies without major differences in safety. An unplanned survival analysis showed a benefit for decitabine, which was not observed at the time of the primary analysis.
Oncogenic K-Ras Regulates Proliferation and Cell Junctions in Lung Epithelial Cells through Induction of Cyclooxygenase-2 and Activation of Metalloproteinase-9 (2008)

Expression of oncogenic K-Ras is frequently observed in non-small-cell lung cancer. However, oncogenic K-Ras is not sufficient to transform lung epithelial cells and requires collaborating signals that have not been defined. To examine the biological effects of K-Ras in nontransformed lung epithelial cells, stable transfectants were generated in RL-65 cells, a spontaneously immortalized lung epithelial cell line. Expression of K-Ras resulted in extracellular signal-regulated kinase (ERK) activation, which mediated induction of cyclooxygenase (COX)-2 and increased prostaglandin E(2) production. Epithelial cells expressing oncogenic K-Ras showed increased proliferation in two- and three-dimensional tissue culture and delayed formation of hollow acinar structures in three-dimensional matrigel cultures. These affects were mediated through COX-2-dependent activation of beta-catenin signaling and inhibition of apoptosis. ERK activation also led to induction of metalloproteinase (MMP)-9 and cleavage of E-cadherin at two specific sites. This resulted in partial disruption of adherens junctions as determined by decreased transepithelial resistance (TER), and disruption of E-cadherin/beta-catenin interactions. An MMP-9 inhibitor reversed the decrease in TER and inhibited beta-catenin signaling. These data indicate that although expression of oncogenic K-Ras does not transform lung epithelial cells, it alters the phenotype of the cells by increasing proliferation and decreasing cell-cell contacts characteristic of epithelial cells.
Room Temperature Operation of Single Electron Transistor Made by STM Nano-Oxidation Process (1995)

A single electron transistor (SET) operating at room temperature was fabricated for the first time using a scanning tunneling microscope (STM) nano-oxidation process. A clear Coulomb staircase with an /spl sim/140 mV period and Coulomb oscillation period of /spl sim/460 mV were observed at 300K.
Perfect Equilibria in a Negotiation Model (1995)

Rubinstein's alternating-offers bargaining model is enriched by assuming that players' payoffs in disagreement periods are determined by a normal form game. It is shown that such a model can have multiple perfect equilibria, including inefficient ones, provided that players are sufficiently patient. Delay is possible even though there is perfect information and the players are fully rational. The length of delay depends only on the payoff structure of the disagreement game and not on the discount factor. Not all feasible and individually rational payoffs of the disagreement game can be supported as average disagreement payoffs. Indeed, some negotiation games have a unique perfect equilibrium with immediate agreement.
Stanford interactive workspaces: a framework for physical and graphical user interface prototyping (2002)

Most smart homes are created evolutionarily by adding more and more technologies to an existing home, rather than being developed on a single occasion by building a new home from scratch. This incremental addition of technology requires a highly flexible infrastructure to accommodate both future extensions and legacy systems without requiring extensive rewiring of hardware or extensive reconfiguration on the software level. Stanford's iStuff (Interactive Stuff) provides an example of a hardware interface abstraction technique that enables quick customization and reconfiguration of Smart Home solutions. iStuff gains its power from its combination with the Stanford Interactive Room Operating System (iROS), which creates a flexible and robust software framework that allows custom and legacy applications to communicate with each other and with user interface devices in a dynamically configurable way. The Stanford Interactive Room (iRoom), while not a residential environment, has many characteristics of a smart home: a wide array of advanced user interface technologies, abundant computation power, and infrastructure with which to coordinate the use of these resources (for more information on the iRoom or the Interactive Workspaces project, please visit http://iwork.stanford.edu). As a result, many aspects of the iRoom environment have strong implications for, and can be intuitively translated to, smart homes. In particular, the rapid and fluid development of physical user interfaces using iStuff and the iROS, which has been demonstrated in the iRoom, is an equally powerful concept for designing and living in smart homes. Before focusing on the details of iStuff, we describe the software infrastructure on which it is based and the considerations that went into designing this infrastructure.
Branched Polyethylene by Ethylene Homopolymerization with<i>meso</i>-Zirconocene Catalyst (1999)

The polyethylene obtained in the presence of the catalyst constituted by the meso isomer of the prototypical zirconocene complex (ethylene)bis(1-indenyl)zirconium dichloride activated by methylalumoxane is characterized by the presence of ethyl branches. The intensities of the 13C NMR signals associated with these branches indicate that there are about 1−2 ethyl groups per 100 monomer units. As a consequence, the melting temperature is 10−15 °C lower than the linear polyethylene obtained with the rac mixture of the same zirconocene complex. On the basis of kinetic evidence, a branching mechanism that involves a β-H transfer to the coordinated ethylene is proposed.
OpenComet: An automated tool for comet assay image analysis (2014)

Reactive species such as free radicals are constantly generated in vivo and DNA is the most important target of oxidative stress. Oxidative DNA damage is used as a predictive biomarker to monitor the risk of development of many diseases. The comet assay is widely used for measuring oxidative DNA damage at a single cell level. The analysis of comet assay output images, however, poses considerable challenges. Commercial software is costly and restrictive, while free software generally requires laborious manual tagging of cells. This paper presents OpenComet, an open-source software tool providing automated analysis of comet assay images. It uses a novel and robust method for finding comets based on geometric shape attributes and segmenting the comet heads through image intensity profile analysis. Due to automation, OpenComet is more accurate, less prone to human bias, and faster than manual analysis. A live analysis functionality also allows users to analyze images captured directly from a microscope. We have validated OpenComet on both alkaline and neutral comet assay images as well as sample images from existing software packages. Our results show that OpenComet achieves high accuracy with significantly reduced analysis time.
Thyrotrophin receptor antibodies in type 1 (insulin-dependent) diabetes mellitus. (1988)

Graves' disease and type 1 (insulin-dependent) diabetes are common autoimmune endocrine disorders which may co-exist. Since the class II HLA-DR3 antigen is associated with both these diseases, and since an association between DR3 and the thyrotrophin receptor antibody (TRAb) has been suggested, we wished to determine whether TRAb levels were increased and were HLA-D related in diabetes mellitus. In 115 clinically euthyroid subjects (33 type 1 diabetics, 82 healthy controls) there was a correlation between age and TRAb levels (r = -0.39, p less than 0.001). TRAb levels were elevated in DR3 subjects (n = 32) compared to an age matched group of non-DR3 (n = 61) subjects [median (range): 18.1 (-1.7 to 47.4) versus 6.7 (-9.8 to 19.1), p less than 0.001]. Diabetic DR3 and control DR3 subjects had similar TRAb levels which were elevated when compared to their respective non-DR3 control group (both p less than 0.001). All but two subjects (both diabetic) had TRAb levels in our normal range. Thus TRAb levels are elevated in the subjects who possess the HLA-DR3 antigen. Since DR3 is found so commonly in type 1 diabetes this phenomenon may partly explain the association with Graves' disease in this patient population.
A new &#x201C;smart parking&#x201D; system based on optimal resource allocation and reservations (2011)

We propose a new “smart parking” system for an urban environment. The system assigns and reserves an optimal resource (parking space) for a user (driver) based on the user's objective function that combines proximity to destination and parking cost, while also ensuring that the overall parking capacity is efficiently utilized. Our approach solves a Mixed Integer Linear Program (MILP) problem at each decision point in a time-driven sequence. The solution of each MILP is an optimal allocation based on current state information and subject to random events such as new user requests or parking spaces becoming available. The allocation is updated at the next decision point ensuring that there is no resource reservation conflict and that no user is ever assigned a resource with higher than the current cost function value. Simulated case studies are included based on parking at part of the Boston University campus showing that we can achieve significant improvement over uncontrolled parking processes or state-of-the-art guidance-based systems. We also describe a laboratory setting where this system has been tested in real time.
Universal environmental surveillance system with instrument cloud technology (2013)

Environmental surveillance system is significant for environmental researches by means of providing abundant physical information around the target environment. In this article, a universal environmental surveillance system that utilizes the instrument cloud technology is presented for any kinds of outdoor or indoor monitoring applications. The architecture of the universal environmental surveillance system is consisted of three main components, including multi-sensors module, data management processor and cloud server. Based on the hierarchical relationship, the system facilitates the process of data transmission. Moreover, the unique data format and the device management list prompt an overwhelming advantage of flexibility on device management during operation. All sensor data are stored in a discrete database referring to the corresponding sensor ID and accessing time. Owing to the cloud technology, researchers can access the data archives everywhere after logging in the website to share the valuable information with one another.
Critical Examination of Platinum Sulfide Precipitation (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCritical Examination of Platinum Sulfide PrecipitationD. S. Jackson and F. E. BeamishCite this: Anal. Chem. 1950, 22, 6, 813–817Publication Date (Print):June 17, 1950Publication History Published online1 May 2002Published inissue 17 June 1950https://pubs.acs.org/doi/10.1021/ac60042a022https://doi.org/10.1021/ac60042a022research-articleACS PublicationsRequest reuse permissionsArticle Views146Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Study of Maternal-Fetal Anti-HL-A Immunization (1973)

Out of 53 cases of sera with an anti-HL-A fetal-maternal immunization, in which the phenotype of the immunizer and the immunized women are known, 27 have antibodies whose specificity is broader than that of the immunizing antigen. The HL-A phenotype of the immunized woman seems to play a part equally important to that of the immunizer in directing the broadening of immunization.
[Combined cosmetic operation of the face]. (2006)

The method of performance of combined cosmetic operation in 58 women patients in 1996-2005 yrs. was analyzed. As a primary procedure for rejuvenation the combined operation of the face and neck skin lifting permits to achieve impressive results, prevents the "lateral bend" and hollow eyes formation. In patients with unfavourable consequences of the earlier performed standard face lifting the conduction of combined operation permits to eliminate them effectively.
CONREAL: Conserved Regulatory Elements Anchored Alignment Algorithm for Identification of Transcription Factor Binding Sites by Phylogenetic Footprinting (2003)

Prediction of transcription-factor target sites in promoters remains difficult due to the short length and degeneracy of the target sequences. Although the use of orthologous sequences and phylogenetic footprinting approaches may help in the recognition of conserved and potentially functional sequences, correct alignment of the short transcription-factor binding sites can be problematic for established algorithms, especially when aligning more divergent species. Here, we report a novel phylogenetic footprinting approach, CONREAL, that uses biologically relevant information, that is, potential transcription-factor binding sites as represented by positional weight matrices, to establish anchors between orthologous sequences and to guide promoter sequence alignment. Comparison of the performance of CONREAL with the global alignment programs LAGAN and AVID using a reference data set, shows that CONREAL performs equally well for closely related species like rodents and human, and has a clear added value for aligning promoter elements of more divergent species like human and fish, as it identifies conserved transcription-factor binding sites that are not found by other methods. CONREAL is accessible via a Web interface at http://conreal.niob.knaw.nl/.
ISOXAZOLINE OXIDES. VIII (1928)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTISOXAZOLINE OXIDES. VIIIE. P. KohlerCite this: J. Am. Chem. Soc. 1928, 50, 1, 221–228Publication Date (Print):January 1, 1928Publication History Published online1 May 2002Published inissue 1 January 1928https://pubs.acs.org/doi/10.1021/ja01388a033https://doi.org/10.1021/ja01388a033research-articleACS PublicationsRequest reuse permissionsArticle Views54Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Organic substituent effects in macrobicyclic (hexaamine)cobalt(III/II) complexes: a new method of obtaining polar substituent constants (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic substituent effects in macrobicyclic (hexaamine)cobalt(III/II) complexes: a new method of obtaining polar substituent constantsGeoffrey A. Lawrance, Peter A. Lay, and Alan M. SargesonCite this: Inorg. Chem. 1990, 29, 23, 4808–4816Publication Date (Print):November 1, 1990Publication History Published online1 May 2002Published inissue 1 November 1990https://pubs.acs.org/doi/10.1021/ic00348a042https://doi.org/10.1021/ic00348a042research-articleACS PublicationsRequest reuse permissionsArticle Views251Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts