gebhart/patrepeval huggingface dataset:
Ring-opening Metathesis Polymerisation derived poly(dicyclopentadiene) based materials (2020)

This review article summarises the academic work in the fields of initiator development, polymer chemistry and physics, composites, self-healing composites, novel processing opportunities and macro-as well as microporous materials.
Tonicity of Resuscitative Fluids Influences Outcome after Spinal Cord Injury (2001)

The results of this investigation with a chronic model of spinal cord injury support the contention that hypertonic saline treatment may provide protection to the spinal cord after mechanical injury.
Towards an Automatic Turing Test: Learning to Evaluate Dialogue Responses (2017)

Ryan Lowe, Michael Noseworthy, Iulian Vlad Serban, Nicolas Angelard-Gontier, Yoshua Bengio, Joelle Pineau. Proceedings of the 55th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers). 2017.
Study on the Method of Pan-Tilt Control in 3D Scene (2015)

In recent years, visualization technology has a qualitative leap in many application field. The research of interactive processing of information in virtual reality is gradually deepening. Combining 3D visualization system with machine operation could realize the integration of observation in virtual scene and instrumentation in reality. This paper introduces the model that controlls the turning of Pan-Tilt based on the visual change in 3D scene. The model establishes the data connection between the 3D software and the two-degree-of-freedom Pan-Tilt platform , and mainly achieves the analysis and conversion between the data collected by 3D visualization software and the data Pan-Tilt received. The experiments verify that the operation in 3D software can change Pan-Tilt monitor`s movements in real time and make the Pan-Tilt always pointing to the current perspective in 3D scene.
Wavelet transform and channel coding for data hiding in video (2002)

This paper presents an approach for video embedding based on the discrete wavelet transform and channel coding. We address the problem of embedding logos and small images within a host video. The algorithm starts with transforming each image or frame of the video sequence into the discrete wavelet domain where their coefficients are grouped into vectors equivalent to the codeword length of the signature data. The host video is not necessary for signature extraction. The method repeatedly merges the signature coefficients at various frames of the host video which provides frequency spread of the watermark to provide robustness against widely varying signal distortions including compression and filtering.
Preparation of p-type InP films on insulating and conducting substrates via chemical vapor deposition (1976)

Polycrystalline p-type InP films were grown on various insulating and conducting substrates, e.g., glass or carbon, via chemical vapor deposition in an open-tube In/HJPC13 flow system. Zn and Cd were used as dopants. Noticeable differences in growth characteristics are observed as compared to epitaxial ayer growth on InP single crystal substrates. Pre l iminary poly-crystal l ine CdS / InP solar cells have a power conversion efficiency of 2.8%. Heterodiodes n-CdS/p- InP have potential for solar cell applications ince the bandgaps and the excellent latt ice match of these materials result in a high solar power conversion efficiency and the stabi l i ty of the two compounds assures good resistance against degradation. Present state-of- the-art single crystal CdS / InP solar cells have a power conversion efficiency of 14 % at air mass 2 (1) and recent accelerated l i fetime tests showed that such cells can be heated in air at 485 ~ for 1 week without significant decay in the device perform-ance (2). InP has a direct bandgap and correspond-ingly low ( ~&lt; 1 ~m) absorption lengths for solar l ight with 0.50 ~m ~&lt; ~, ~&lt; 0.96 ~m. Over this entire &quot;win-dow &quot; of the InP/CdS cell, InP grain sizes of a few micrometers hould thus uffice for efficient collection of photogenerated minor ity carr ier electrons. The cell is therefore an attractive candidate for production in thin film form. At the present stage of development, the preparat ion of polycrystal l ine CdS / InP solar cell hinges on the fabrication of p- type films of InP on a suitable substrate material. In this paper we report on the growth of poly-crystal l ine films of p- type InP on transparent in-sulators, and on conducting substrates that provide a large area contact o the InP, uti l izing the In /H JPC ls growth method (3). In this system, the temperature dependence of the equi l ibr ium constant of the reaction InP(s) + HCI(g) ~ InC l (g) + 89 + Y4P4(g) regulates transport of InP from an InP crust on an In
InBr<sub>3</sub>-Catalyzed Friedel−Crafts Addition of Indoles to Chiral Aromatic Epoxides:  A Facile Route to Enantiopure Indolyl Derivatives (2002)

Aromatic optically active epoxides can be opened in a regioselective and clean way with indoles in the presence of catalytic amount of InBr3 (1 mol %). The reaction takes place with a SN2 pathway affording the 2-aryl-2-(3'-indolyl)ethan-1-ols with excellent enantioselectivity (ee up to 99%).
Epidemiology of anthracycline cardiotoxicity in children and adults. (1998)

Anthracyclines, potent cytotoxic agents used to treat a broad spectrum of malignancies, are limited in their use by an attendant risk of cardiotoxicity. Malignancies affect all age ranges, and anthracyclines are used in all age ranges, thereby exposing a broad population of patients to the development of heart disease. For some treated patients, anthracyclines affect cardiac muscle, resulting in cardiomyopathy. The type and degree of cardiomyopathy, as well as when during or after treatment the condition occurs, are dependent on what risk factors are present. Age is a major risk factor. Children and adults may develop restrictive and dilated cardiomyopathy. The length of subsequent survival and amount of subsequent somatic growth may influence late anthracycline-associated cardiac outcome. Early cardiotoxicity, occurring during or within 1 year of completion of treatment, is the largest risk factor for the development of late cardiotoxicity, which occurs beyond a year of completion of treatment. Risk factors, which appear to be specific for early cardiotoxicity in children, include black race, trisomy 21, and the use of amsacrine therapy after anthracycline therapy. More cardiotoxic effects are seen in survivors of childhood cancer, the longer from completion of treatment a patient is followed. Cumulative as well as peak anthracycline doses affect adults and children alike, and cardiotoxicity occurs early and late. In adults, left ventricular contractility is affected by anthracyclines. Children may manifest impairment of left ventricular contractility and increased afterload due to thinning of left ventricular walls. Patients with an early presentation of depressed left ventricular contractility are likely to show progression of cardiac disease with time. In addition, female gender appears to affect early and late cardiotoxicity in both adults and children, although this risk factor has been described predominantly in the survivors of childhood cancer. Thus, although anthracycline chemotherapy has improved overall survivorship of patients with cancer, there is a significant risk of cardiotoxicity associated with this class of drugs.
Size‐ and Shape‐Control of Crystalline Zinc Oxide Nanoparticles: A New Organometallic Synthetic Method (2005)

Abstract A novel organometallic synthetic method has been developed for the preparation of crystalline ZnO nanoparticles of controlled size and shape. Isotropic nanoparticles with a mean size between 3 and 6 nm and nanorods with a mean diameter of 3–4 nm and length up to 120 nm have been obtained in this way. This synthetic method takes advantage of the exothermic reaction of the precursor Zn(c‐C 6 H 11 ) 2 ( 1 ) toward moisture and air and involves the presence of long‐alkyl‐chain amines as stabilizing ligands. The influence of the different experimental parameters (concentration, solvent, nature of the ligand, time, and temperature) on the size and shape of the ZnO nanoparticles has been studied, together with the mechanism of their formation, by NMR spectroscopy, transmission electron microscopy, and X‐ray diffraction techniques. The nanoparticles prepared in this way can be dissolved in most of the common organic solvents, forming colloidal solutions. The surface state of the nanoparticles as well as the possibility of forming luminescent solutions from which regular monolayers can be deposited are also reported.
A Role for Old Yellow Enzyme in Ergot Alkaloid Biosynthesis (2010)

Ergot alkaloids, secondary metabolites produced by filamentous fungi, elicit a diverse array of pharmacological effects. The biosynthesis of this class of natural products has not been fully elucidated. Here we demonstrate that a homologue of Old Yellow Enzyme encoded in the Aspergillus fumigatus ergot gene cluster catalyzes reduction of the alpha,beta unsaturated alkene of chanoclavine-I aldehyde 3. This reduction, which yields dihydrochanoclavine aldehyde, facilitates an intramolecular reaction between a secondary amine and aldehyde to form the D ring of the ergot alkaloid structural framework.
Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases (2017)

The chemokine receptors CXCR1/2 and their ligand CXCL8 are essential for the activation and trafficking of inflammatory mediators as well as tumor progression and metastasis. The CXCL8-CXCR1/2 signaling axis is involved in the pathogenesis of several diseases including chronic obstructive pulmonary diseases (COPD), asthma, cystic fibrosis and cancer. Interaction between CXCL8 secreted by select cancer cells and CXCR1/2 in the tumor microenvironment is critical for cancer progression and metastasis. The CXCL8-CXCR1/2 axis may play an important role in tumor progression and metastasis by regulating cancer stem cell (CSC) proliferation and self-renewal. During the past two decades, several small-molecule CXCR1/2 inhibitors, CXCL8 releasing inhibitors, and neutralizing antibodies against CXCL8 and CXCR1/2 have been reported. As single agents, such inhibitors are expected to be efficacious in various inflammatory diseases. Several preclinical studies suggest that combination of CXCR1/2 inhibitors along with other targeted therapies, chemotherapies, and immunotherapy may be effective in treating select cancers. Currently, several of these inhibitors are in advanced clinical trials for COPD, asthma, and metastatic breast cancer. In this review, we provide a comprehensive analysis of the role of the CXCL8-CXCR1/2 axis and select genes co-expressed in this pathway in disease progression. We also discuss the latest progress in developing small-molecule drugs targeting this pathway.
Redesigning the substrate specificity of ω‐aminotransferase for the kinetic resolution of aliphatic chiral amines (2007)

Substrate specificity of the omega-aminotransferase obtained from Vibrio fluvialis (omega-ATVf) was rationally redesigned for the kinetic resolution of aliphatic chiral amines. omega-ATVf showed unique substrate specificity toward aromatic amines with a high enantioselectivity (E > 100) for (S)-enantiomers. However, the substrate specificity of this enzyme was much narrower toward aliphatic amines. To overcome the narrow substrate specificity toward aliphatic amines, we redesigned the substrate specificity of omega-ATVf using homology modeling and the substrate structure- activity relationship. The homology model and the substrate structure-activity relationship showed that the active site of omega-ATVf consists of one large substrate-binding site and another small substrate-binding site. The key determinant in the small substrate-binding site was D25, whose role was expected to mask R415 and to generate the electrostatic repulsion with the substrate's alpha-carboxylate group. In the large substrate-binding site, R256 was predicted to recognize the alpha-carboxylate group of substrate thus obeying the dual substrate recognition mechanism of aminotransferase subgroup II enzymes. Among the several amino acid residues in the large substrate-binding site, W57 and W147, with their bulky side chains, were expected to restrict the recognition of aliphatic amines. Two mutant enzymes, W57G and W147G, showed significant changes in their substrate specificity such that they catalyzed transamination of a broad range of aliphatic amines without losing the original activities toward aromatic amines and enantioselectivity.
Light Induced LC Alignment on the Isotropic Non-Photosensitive Surface (1999)

Abstract We observed planar alignment of nematic liquid crystal (LC) 5CB on a fused quartz surface upon illumination with polarized UV light. The axis of easy orientation is perpendicular to the polarization of the incident light. The value of the anchoring energy increases with increase of the illumination dozes up to 10−4 erg/cm2. We propose that the phenomena observed results from light-induced rearrangement of the LC layer adsorbed on the quartz surface.
A Complementary RF-LDMOS Architecture Compatible with 0.13μm CMOS Technology (2006)

In this paper, we present a modular and reliable complementary RF LDMOS (laterally diffused MOS) architecture fully compatible with a 0.13 mum CMOS platform. We demonstrate BV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DS</sub> *f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> values up to 560 and 210 GHzV, respectively, for N- and PLDMOS transistors. A major advantage of the proposed process flow is that the drift region of N- and PLDMOS transistors can be independently optimized for different BV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DS</sub> without affecting the V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub>
The influence of light on modulation of the human vestibulo-ocular reflex (2000)

The goal of this study was to investigate the influence of light, without retinal slip information, on the ability to generate eye movements to compensate for head rotations. Subjects were rotated sinusoidally at 1.0, 2.0 or 3.0 Hz at a peak velocity of 30 deg/sec while they: 1) performed mental arithmetic in darkness; 2) attempted to view the remembered location of a stationary target in darkness; 3) attempted to view the remembered location of the stationary target through translucent contact lenses that allowed the passage of light but did not provide any target information (ganzfeld stimulus); 4) directly viewed the illuminated stationary target. The gain of compensatory eye movements was least while subjects viewed through the translucent contact lenses (median = 0.76), intermediate while subjects either performed mental arithmetic in darkness (median = 0.84) or attempted to view the remembered location of the target in darkness (median = 0.84), and greatest if they actually viewed the target (median = 0.95). Our findings suggest that factors other than light alone account for the increased gain of compensatory eye movements that occurs when subjects view rather than imagine a stationary target.
Magnetic Field Design of a Superconducting Magnet for a FFAG Accelerator (2005)

A superconducting magnet for a Fixed Field Alternating Gradient (FFAG) accelerator is proposed. The static magnetic field is required to be proportional to the k-th power of the orbit radius where k is the geometrical field index of the accelerator. The left/right asymmetric coil with elliptical aperture is introduced to maximize the horizontal aperture with a compact magnet design. The 3D coil configuration is designed to meet the requirement in terms of integral magnetic field. The 3D magnetic field is evaluated and the field integral along the beam trajectory satisfies the beam optics requirement of the FFAG accelerator.
DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA (2014)

Acute lymphoblastic leukemia (ALL) is a disseminated malignancy of B- or T-lymphoblasts which imposes a rapid and accurate diagnostic process to support an optimal risk-oriented therapy and thus increase the curability rate. The need for a precise diagnostic algorithm is underlined by the awareness that both ALL therapy and related success rates may vary greatly between ALL subsets, from standard chemotherapy in patients with standard-risk ALL, to allotransplantation (SCT) and targeted therapy in high-risk patients and cases expressing suitable biological targets, respectively. This review summarizes how best to identify ALL and the most relevant ALL subsets.
A broadband and deep-TX self-interference cancellation technique for full-duplex and frequency-domain-duplex transceiver applications (2018)

Full-Duplex (FD) radios, capable of simultaneously transmitting and receiving on the same frequency, have evolved as one method to address future demand for higher data-rates. Although recent highly integrated full-duplex radios [1-4] show promise towards improving spectral efficiency by >1.9x [5], mitigating transmitter (TX) self-interference (SI) for broad-bandwidth signals remains a major challenge, particularly for longer range transceivers requiring a high-output-power PA. This paper describes a CMOS transceiver with a deep TX SI cancellation performance over a very wideband (65dBc/80MHz and 70dBc/40MHz).
Bioelectrochemical Conversion of Urea on Carbon Black Electrode and Application (2013)

The amperometric biosensor for urea determination is designed. The decomposition product of urea produced by urease is oxidized in an electrochemical way. The specially developed carbon black (CB) paste electrode is covered by a semipermeable membrane containing immobilized urease. Three types of the urea biosensor action are identified. At low electrode working potentials (0-0.1 V), one electron electrochemical oxidation of carbamic acid can be monitored. Cation-radical of the carbamic acid whereupon undergoes dimerization to hydrazine. At higher electrode potentials (0.2-0.5 V), the electro-oxidation of both carbamic acid and hydrazine are observed. In addition, at more high potential (> 0.6 V), electro-oxidation of ammonia and amination of the electrode surface are observed. The first type of biosensor is less serviceable because of the slow equilibrium process. However, the third type of biosensor, because of the high potential of action and irreproducible response, is also not valuable. The working potential of 0.35 V is selected for optimal urease-CB electrode operation, and the response properties of the electrode are also characterized. The biosensor possesses a linear range of response up to 5 mM of urea, a coefficient of variation equaling 3.7%, a response time of 1.5 min. The biosensor is tested for urea detection in milk.
Narrowband Wireless Access for Low-Power Massive Internet of Things: A Bandwidth Perspective (2017)

LPWAN is a type of wireless telecommunication network designed to allow long range communications with relaxed requirements on data rate and latency between the core network and a high-volume of battery-operated devices. This article first reviews the leading LPWAN technologies on both unlicensed spectrum (SIGFOX, and LoRa) and licensed spectrum (LTE-M and NB-IoT). Although these technologies differ in many aspects, they do have one thing in common: they all utilize the narrow-band transmission mechanism as a leverage to achieve three fundamental goals, that is, high system capacity, long battery life, and wide coverage. This article introduces an effective bandwidth concept that ties these goals together with the transmission bandwidth, such that these contradicting goals are balanced for best overall system performance.
T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses (2014)

Full T-cell activation critically depends on the engagement of the TCR (T-cell receptor) in conjunction with a second signal by co-stimulatory receptors that boost the immune response. In the present study we have compared signalling patterns induced by the two co-receptors CD2 and CD28 in human peripheral blood T-cells. These co-receptors were previously suggested to be redundant in function. By a combination of multi-parameter phosphoflow cytometry, phosphokinase arrays and Western blot analyses, we demonstrate that CD2 co-stimulation induces phosphorylation of the TCR-proximal signalling complex, whereas CD28 activates distal signalling molecules, including the transcription factors NF-κB (nuclear factor κB), ATF (activating transcription factor)-2, STAT3/5 (signal transducer and activator of transcription 3/5), p53 and c-Jun. These signalling patterns were conserved in both naïve and effector/memory T-cell subsets. We show that free intracellular Ca(2+) and signalling through the PI3K (phosphoinositide 3-kinase)/Akt pathway are required for proper CD28-induced NF-κB activation. The signalling patterns induced by CD2 and CD28 co-stimulation lead to distinct functional immune responses in T-cell proliferation and cytokine production. In conclusion, CD2 and CD28 co-stimulation induces distinct signalling responses and functional outcomes in T-cells.
Magnetisk køling - køleteknologi med en varm fremtid (2013)

En stor del af verdens elektricitetsforbrug anvendes til køling. Der er derfor stort fokus på at nedbringe energiforbruget af køleskabe. Magnetisk køling, der udnytter, at visse materialer skifter temperatur, når de kommer ind i et magnetfelt, er et lovende og energieffektivt alternativ til den traditionelle køleteknologi.
Expanding the analogy between phosphorus-carbon and carbon-carbon double bonds (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleExpanding the analogy between phosphorus-carbon and carbon-carbon double bondsFrancois MatheyCite this: Acc. Chem. Res. 1992, 25, 2, 90–96Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February 1992https://pubs.acs.org/doi/10.1021/ar00014a006https://doi.org/10.1021/ar00014a006research-articleACS PublicationsRequest reuse permissionsArticle Views584Altmetric-Citations104LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts