gebhart/patrepeval huggingface dataset:
Streaming Session Mobility across Multiple Devices in Mobile IPTV Environments (2009)

Since digital media is being combined into all aspects of our lives and an ubiquitous broadband networks are being surfaced, people expect to extend the consumption of these services on any device, anytime and anywhere. This new demand requires the flexible service adaptation to user requirements and to device capabilities. Specifically, various access networks and devices with different capabilities, in Mobile IPTV environments, are used to create and consume across multiple devices in a seamless and transparent way. In order to enhance higher user satisfaction in Mobile IPTV services across heterogeneous devices and access networks, service session mobility and device-based content adaptation are an ingredient. Recently, the realtime streaming protocol (RTSP) has been adopted for steaming by several standards development organization (SDOs) and session initiation protocol (SIP) has been used for multimedia conversational service. Thought several session migration mechanisms based on SIP for conversional service has been proposed, SIP is unfit for the multimedia streaming services since these do not support streaming control functions, such as pause, play, fast forward and rewind. Therefore, this paper addresses the service session migration scenarios in Mobile IPTV environments and describes how to use the RTSP for streaming service session migration between multiple devices, especially session split and session merge across multiple devices.
A high-frequency-linked single phase UPS with power factor correction scheme (2002)

The single-phase switched mode rectifier (SMR) with a high-frequency isolation transformer link has some advantages as an electrically-isolated AC/DC power conversion circuit for small scale UPS applications. This UPS is capable of eliminating harmonic currents as well as realizing an isolation between AC input and DC output power stage by means of inserting a compact high frequency transformer. Each isolated SMR designed for 2 kVA, 3 kVA and 5 kVA UPS is developed and put into practice. This paper presents a high-frequency link SMR circuit configuration and its control strategy, together with the experimental results of the developed UPS.
Jugend und Drogen - Eine Studie zum wachsenden Bedarf an jungenspezifischer Suchtprävention (2004)

Im Rahmen der vorliegenden Studie wurde der Substanzkonsum bei 11-bis 15jährigen an einer repräsentativen Stichprobe für Deutschland untersucht. Ziel war es, aktuelle Informationen über die geschlechtsspezifische Verbreitung der einzelnen Verhaltensweisen in dieser Altersgruppe zu erhalten. Wie die Ergebnisse zeigen, ist die Konsumhäufigkeit von Alkohol und Cannabis nach wie vor stark geschlechtsspezifisch geprägt: Jungen trinken häufiger regelmäßig Alkohol, berichten häufiger von alkoholbedingten Rauscherfahrungen und erleben ihren ersten Alkoholrausch früher als Mädchen. Zudem berichten mehr Jungen als Mädchen von Erfahrungen mit Cannabis. Beim Tabakkonsum hingegen ergibt sich eine andere Tendenz. Im Gegensatz zu früheren Jahren zeigen sich heute keine geschlechtsspezifischen Unterschiede im Tabakkonsum. Allerdings ist das Einstiegsalter bei Jungen niedriger als bei Mädchen. Es kann zudem davon ausgegangen werden, daß diese Angleichung der Konsumquoten nur im Bereich gemäßigter Verhaltensmuster stattgefunden hat. Die Ergebnisse weisen mit Nachdruck darauf hin, daß präventive Maßnahmen stärker als bislang auf Jungen auszurichten sind. Nur so kann die Effektivität der Angebote gesteigert werden.
Comparison of Army Hand and Arm Signals to a Covert Tactile Communication System in a Dynamic Environment (2006)

This study was conducted jointly by the U.S. Army Research Laboratory and the University of Central Florida. The purpose of this experiment was to evaluate Soldiers abilities to interpret and respond to tactile commands compared to their abilities to interpret and respond to standard visual hand and arm signals given from leaders in front of and behind them during movement. The tactile belt, developed by UCF, consists of eight tactors (tactile drivers) arranged equidistant around the Soldier's waist. Individual or multiple tactors can be activated by an operator using a remote wireless control system. Infantry Soldiers, wearing their standard uniforms and body armor, negotiated a woodland individual movement technique (IMT) obstacle course while simulating a combat patrol. Tactile and visual hand and arm signals were sent to the Soldiers as they negotiated the course. The accuracy of signal interpretation and response times was recorded. The tactile signal patterns were intuitive and easy for the Soldiers to understand; less than 10 minutes training was required for the Soldiers to become accurate in interpreting the four tactile signals used during the experiment. Results demonstrated that Soldiers performing IMT were able to receive, interpret, and accurately respond to the tactile commands faster than when the information was passed by leaders in the front of a wedge formation and leaders in the back of a wedge formation using conventional hand and arm signals. Soldiers also commented that they were better able to focus more attention on negotiating obstacles and on area situational awareness when receiving tactile signals than when maintaining visual contact with their leaders in order to receive standard hand and arm signals.
Nanostructured cobalt and manganese oxide clusters as efficient water oxidation catalysts (2010)

Recent development of new methods of preparing cobalt oxide and manganese oxide clusters has led to oxygen evolving catalysts that operate under mild conditions and modest overpotentials at rates approaching practical utility. Synthesis of nanostructured Co3O4 and Mn oxide clusters in mesoporous silica scaffolds affords catalysts with very high densities of surface metal sites per projected area, with the silica environment providing stability in terms of dispersion of the clusters and prevention of restructuring of catalytic surface sites. Stacking of the nanoclusters of these earth abundant, durable oxide catalysts in the scaffold results in turnover frequencies per projected area that are sufficient for keeping up with the photon flux at high solar intensity. Opportunities for expanding the metal oxide/silica interface approach to heterogeneous water oxidation catalysis to a more general approach for multi-electron catalyst designs based on core/shell constructs are discussed. The results are reviewed in the context of all-inorganic materials for catalytic water oxidation reported recently from other laboratories, in particular electrodeposits generated from Co phosphate solutions, a molecular water oxidation catalyst based on a polyoxotungstate featuring a Co oxide core, and Mn oxide materials with incorporated Ca ions.
Microprocessor power optimization through multi-performance device insertion (2004)

A paradigm shift for multi-performance device insertion from optimizing product-level performance to total power is elucidated. The key limitations of a performance-based insertion methodology are reviewed, where an increase in standby current is sacrificed for an unobservable clock frequency gain. The power optimization, which is based on nodal activity factors and state probabilities, enables a 5% to 8% total power reduction on three mature mega-block designs from two separate 90nm technology generation microprocessors while maintaining constant performance.
ChemInform Abstract: Synthesis and Reactions of Nucleoside 5′‐Diphosphate Imidazolide. A Nonenzymatic Capping Agent for 5′‐Monophosphorylated Oligoribonucleotides in Aqueous Solution. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Negotiating access within Wiki (2004)

A wiki hypertext is typically accessible and editable by all. While this removes impediments to collaboration, it often deters participants who would rather incubate ideas before bringing them to the group. This is especially the case where creative ideas are at stake. Creating additional wikis with restricted access is a costly solution: it requires participants to distinguish between and navigate between wikis; it requires administrators to construct wikis and their access rules; and it does not account for the movement of content from private to public. In this paper, we describe a system that augments the hypertext in order to solve these problems. This system automatically creates and maintains access rules in response to browsing and editing of the wiki hypertext. In doing so, it improves the targeting of documents in the hypertext, and identifies significant collections of documents and participants.
The Vilsmeier-Haack aroylation of pyrroles reexamined (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Vilsmeier-Haack aroylation of pyrroles reexaminedJulian White and George McGillivrayCite this: J. Org. Chem. 1977, 42, 26, 4248–4251Publication Date (Print):December 1, 1977Publication History Published online1 May 2002Published inissue 1 December 1977https://pubs.acs.org/doi/10.1021/jo00862a016https://doi.org/10.1021/jo00862a016research-articleACS PublicationsRequest reuse permissionsArticle Views1673Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Flammability and fire resistance of composites reinforced by natural fibers (2008)

Abstract Natural fiber‐reinforced composites are more and more frequently applied to building industry and transportation. Therefore, the knowledge of their behavior during fire is of high importance. Flammability is one of very important parameters that often limits the application of composites to a given area. It is well‐known that addition of lignocellulosic fibers to polymer changes mechanical properties of the product obtained. However, little information is available on their fire performance. The purpose of this review was to obtain fire performance data for several types of composites reinforced by lignocellulosic fibers. Copyright © 2008 John Wiley & Sons, Ltd.
Active Damping Wheel-Torque Control System to Reduce Driveline Oscillations in a Power-Split Hybrid Electric Vehicle (2009)

Power-split hybrid electric vehicles (HEVs) provide a great opportunity to improve fuel economy and emissions. This power-split hybrid system has inherent low damping in driveline since it uses planetary gear sets to directly connect the engine, the generator, and the motor to the driveline for improved vehicle efficiency, thus lacking a clutch or a torque converter that provides the conventional vehicles with driveline damping. When they are subjected to acceleration or disturbances, the low damping in the driveline may cause torsional vibrations. Since the power-split control system is closed loop in nature, these torsional vibrations can result in sustained driveline oscillations. These oscillations can be very objectionable to the driver as they affect the vehicle's drivability. In this paper, we present the design of an active damping wheel-torque control system to suppress such oscillations to improve the drivability of a power-split HEV. To the best of our knowledge, this is the first reported use of an active damping wheel-torque control system to suppress the driveline oscillations in a power-split HEV. Simulations in a power-split HEV environment and experimental tests in the field using a Ford Escape Hybrid demonstrate the effectiveness of the proposed system in suppressing the oscillations. The driveline disturbances are suppressed to below the perceptible level of wheel torque (<100 Nmiddotm). Additional simulations are performed to validate the system to other key factors that can affect its performance. Even with increased motor/generator disturbances by a factor of 2 and change in driveline stiffness of plusmn50%, the proposed control system can still effectively suppress driveline oscillations and thereby improve drivability.
Counting sequences, Gray codes and lexicodes (2006)

A counting sequence of length n is a list of all 2^n binary n-tuples (binary codewords of length n). The number of bit positions where two codewords differ is called the Hamming distance of these two codewords. The average Hamming distance of a counting sequence of length n is defined as the average Hamming distance between the 2^n pairs of successive codewords, including the pair of the last and the first codeword. A counting sequence of length n which has average Hamming distance equal to n-1/2 is called a maximum counting sequence. The number of bit changes in bit position i, in a counting sequence of length n is called the transition count of bit position i. If a counting sequence of length n has the property that the difference between any two bit positions is at most 2, the sequence is called balanced. We introduce a construction for balanced maximum counting sequences for every codeword length n>0, n not equal 4, which implies a proof of a longstanding conjecture of Robinson and Cohn in [IEEE Trans. Computers, vol. C-30, pp. 17-23, 1981]. A counting sequence of length n which has the property that any two successive codewords in the list have the same Hamming distance is called uniform. We introduce a heuristic construction how to construct uniform sequences. This construction occasionally produces balanced sequences, and so gives a partial answer to another conjecture of Robinson and Cohn dealing with the existence of balanced uniform counting sequences [IEEE Trans. Computers, vol. C-30, pp. 17-23, 1981]. A cyclic Gray code of length n is a uniform sequence of length n with Hamming distance exactly one between any two successive codewords. We introduce a construction of Gray codes satisfying the property that either all transition counts are equal to the same power of two, or are all equal to two consecutive powers of two, which proves the conjecture of Wagner and West in [Congressus Numerantium, vol. 80, pp. 217-223, 1991]. Furthermore, we also introduce a construction of Gray codes of length n>0, n not equal 3, inducing the complete graph K_n, thus providing the complete answer for an open problem suggested by Wilmer and Ernst in [Discrete Mathematics, vol. 257, pp. 585-598, 2002]. Moreover, we derive the separability function of the reflected N-ary Gray codes. We also introduce a simple method for the construction of cyclic N-ary Gray codes, and for the construction of constant weight N-ary Gray codes. The separability functions of these codes are derived as well. In the remaining part of the thesis we present a greedy algorithm for the construction of a large class of linear q-ary lexicodes which generalizes the algorithms in several other papers. By applying this method, one can produce linear lexicodes which cannot be constructed by previous algorithms. Especially, we discuss some interesting properties of self-orthogonal ternary lexicodes.
ChemInform Abstract: SYNTHESIS AND BIOLOGIC DISTRIBUTION OF MERCAPTO DERIVATIVES OF PALMITIC ACID (1979)

Abstract Die Palmitinsäure (II) und Dicarbonsäure (VI), deren Herstellung im Formelschema beschrieben ist, sowie 2‐Mercaptopalmitinsäure werden auf ihre Verteilung in Ratten als 35S‐markierte Verbindungen untersucht.
Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Cellular Activity (2014)

Both c-Met and VEGFR-2 are important targets for cancer therapies. Here we report a series of potent dual c-Met and VEGFR-2 inhibitors bearing an anilinopyrimidine scaffold. Two novel synthetic protocols were employed for rapid analoguing of the designed molecules for structure-activity relationship (SAR) exploration. Some analogues displayed nanomolar potency against c-Met and VEGFR-2 at enzymatic level. Privileged compounds 3a, 3b, 3g, 3h, and 18a exhibited potent antiproliferative effect against c-Met addictive cell lines with IC50 values ranged from 0.33 to 1.7 μM. In addition, a cocrystal structure of c-Met in complex with 3h has been determined, which reveals the binding mode of c-Met to its inhibitor and helps to interpret the SAR of the analogues.
Transportation Modes Classification Using Sensors on Smartphones (2016)

This paper investigates the transportation and vehicular modes classification by using big data from smartphone sensors. The three types of sensors used in this paper include the accelerometer, magnetometer, and gyroscope. This study proposes improved features and uses three machine learning algorithms including decision trees, K-nearest neighbor, and support vector machine to classify the user's transportation and vehicular modes. In the experiments, we discussed and compared the performance from different perspectives including the accuracy for both modes, the executive time, and the model size. Results show that the proposed features enhance the accuracy, in which the support vector machine provides the best performance in classification accuracy whereas it consumes the largest prediction time. This paper also investigates the vehicle classification mode and compares the results with that of the transportation modes.
The 12‐15‐lipoxygenase is a modulator of Alzheimer's‐related tau pathology <i>in vivo</i> (2013)

12/15-lipoxygenase (12-15LO) is a lipid-peroxidizing enzyme widely expressed in the central nervous system where it has been involved in the neurobiology of Alzheimer's disease (AD) because it modulates amyloid beta (Aβ) and APP processing. However, its biological effect on tau protein is unknown. We investigated the effect of 12-15LO on tau levels and metabolism in vivo and in vitro and the mechanism involved by using genetic and pharmacologic approaches. While no significant differences were observed in the levels of total tau for both groups, compared with controls, Tg2576 mice overexpressing 12-15LO had elevated levels of phosphorylated tau at two specific epitopes, Ser 202/Thr 205 and Ser 396. In vitro and in vivo studies show that 12-15LO modulates tau metabolism specifically via the cdk5 kinase pathway. Associated with these changes were biochemical markers of synaptic pathology. Finally, 12-15LO-dependent alteration of tau metabolism was independent from an effect on Aβ. Our findings reveal a novel pathway by which 12-15LO modulates endogenous tau metabolism making this protein an appealing pharmacologic target for treatment of AD and related tauopathies.
Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]-quinoxaline-2,3-dione and related quinoxalinediones: characterization of .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity (1995)

Four related series of substituted quinoxalinediones containing angular fused-piperidine rings have been synthesized as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists with potential as neuroprotective agents, primarily for acute therapy immediately following a stroke. The compounds were tested for their affinity to the AMPA, kainate, and strychnine-insensitive glycine receptor sites. In AMPA binding, the most potent compound was 27a (PNQX, IC50 = 63 nM), with affinity comparable to the literature standard 1 (NBQX, IC50 = 52 nM). Other 6-nitro analogs from the 9-aza series had comparable affinity at the AMPA receptor, as did 6-nitro-8-aza derivatives such as 13a (iPNQX, IC50 = 290 nM). The receptor binding profile of 27a differed from that of 1 in that 27a possessed significant affinity at the glycine site of the N-methyl-D-aspartate (NMDA) receptor, whereas 1 was essentially inactive. Three compounds, 26c, 26d, and 26e, demonstrated moderate selectivity for kainate relative to AMPA receptors. Selected analogs reported herein as well as in the literature were superimposed to generate an AMPA pharmacophore model, and 6-substituted compounds from the PNQX and iPNQX series were combined and analyzed via quantitative structure-activity relationship techniques. Compounds with high affinity at non-NMDA receptors were further characterized in functional assays in neuronal cell culture and in a cortical wedge preparation. Both 1 and 27a showed comparable effectiveness in an AMPA- and kainate-induced excitoxicity assay. Both inhibited AMPA-induced depolarizations in the cortical wedge. However, 27a also inhibited spontaneous epileptiform discharges in the cortical wedge (reversed by glycine), while 1 was ineffective. The combination of AMPA and NMDA antagonist activity may contribute to the 30-fold difference in potency between 27a and 1 in the maximal electroshock convulsant assay in mice. The significant in vivo potency of 27a suggests that it has potential clinical utility.
Channel crosstalk correction in suspension and imaging mass cytometry (2017)

ABSTRACT Mass cytometry enables simultaneous analysis of over 40 proteins and their modifications in single cells through use of metal-tagged antibodies. Compared to fluorescent dyes, the use of pure metal isotopes strongly reduces spectral overlap among measurement channels. Crosstalk still exists, however, caused by isotopic impurity, oxide formation, and mass cytometer properties. Spillover effects can be minimized, but not avoided, by following a set of constraining rules when designing an antibody panel. Generation of such low crosstalk panels requires considerable expert knowledge, knowledge of the abundance of each marker and substantial experimental effort. Here we describe a novel bead-based compensation workflow that includes R-based software and a web tool, which enables correction for interference between channels. We demonstrate utility in suspension mass cytometry and show how this approach can be applied to imaging mass cytometry. Our approach greatly simplifies the development of new antibody panels, increases flexibility for antibody-metal pairing, improves overall data quality, thereby reducing the risk of reporting cell phenotype and function artifacts, and greatly facilitates analysis of complex samples for which antigen abundances are unknown.
Preparation and Selected Reactions of <i>t</i>‐Butyl 2‐Methylene‐3‐oxoalkanoates (1991)

Abstract The title class of 1,1‐diactivated ethylenes has been prepared in two steps from aldehydes and t‐ butyl acrylate by (i) DABCO‐catalyzed coupling to give t ‐butyl 2‐(hydroxyalkyl)‐2‐propenoates 11 and (ii) low‐temperature Jones oxidation, followed by swift work up at low temperature. The resulting t ‐butyl 2‐methylene‐3‐oxoalkanoates 12 are stabilized by sterically demanding and also by aromatic groups R. For primary unhindered alkyl groups, stability is low. The compounds enter into Michael reactions, hetero Diels‐Alder additions with enol ethers, and self‐dimerization.