gebhart/patrepeval huggingface dataset:
Dynamic bandwidth allocation for B-ISDN based on end-to-end delay estimates (2003)

A novel dynamic bandwidth allocation procedure that combines the desirable attributes of bandwidth advertising and techniques based on only responding to source queue threshold violations is described. The proposed methodology uses end-to-end delay estimates to infer the available unused bandwidth along the virtual path connecting the source to the destination. Bursts of traffic exceeding the negotiated rate from the source are violation tagged and allowed to enter the network if unused bandwidth increases the confidence that the tagged cells will be delivered. Negotiated bandwidth request and release procedures are based on estimates of the traffic flow. The performance results for this scheme are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Report on Acetylsalicylic Acid, Acetophenetidin, and Caffeine (1959)

Journal Article Report on Acetylsalicylic Acid, Acetophenetidin, and Caffeine Get access Gordon Smith Gordon Smith Associate Referee Food and Drug Administration, Department of Health, Education, and Welfare, New York 14, N.Y Search for other works by this author on: Oxford Academic Google Scholar Journal of Association of Official Agricultural Chemists, Volume 42, Issue 3, 1 August 1959, Pages 462–463, https://doi.org/10.1093/jaoac/42.3.462 Published: 03 February 2020
The Impact of Cell Phone Noncoverage Bias on Polling in the 2004 Presidential Election (2006)

Despite concerns that the accuracy of pre-election telephone polls would be harmed by the omission of voters who could be reached only by cell phone, most national polls performed well in predicting President George W. Bush’s reelection, and state polls were generally accurate as well. The national exit poll conducted by the National Election Pool found that 7% of electionday voters had cell phone service but no land line; younger voters were far more likely to be cellonly: 19% among those 18-24 and 20% among those 25-29. Within these two youngest age cohorts, cell-only voters were significantly more likely to be single and childless. While cellonly voters were more supportive of John Kerry than voters overall, they were similar to voters within their own age cohort. Because of this, pre-election telephone surveys that weighted their data appropriately by age were not significantly biased by the absence of the cell-only voters.
Pharmacokinetics of the in vivo and in vitro conversion of 9-nitro-20(S)-camptothecin to 9-amino-20(S)-camptothecin in humans, dogs, and mice. (1994)

We have determined that 9-nitro-20(S)-camptothecin (9NC) converts to 9-amino-20(S)-camptothecin (9AC) in humans, dogs, and mice. Following a single oral dose of 0.1 mg/kg of 9NC, the human plasma concentration reached a maximum concentration of 483 ng/ml at 3.4 h with an area under the curve (AUC) of 2.6 micrograms.h/ml and a half-life of 2.5 h. As conversion of 9NC to 9AC occurred, the maximum calculated concentration of 9AC was 14.0 ng/ml at 10.3 h with an AUC of 311 ng.h/ml and a half-life of 7.1 h. Following a single oral dose of 1.0 mg/kg of 9NC, the maximum concentration of 9NC in the human volunteer was 1247 ng/ml at 5.3 h with an AUC of 17194 ng.h/ml and a half-life of 4.9 h. In this human, the Cmax of 9AC was 208 ng/ml at 17.2 h; the AUC was determined to be 9121 ng.h/ml, and the half-life was 13.1 h. In a dog after a single oral dose of 1.0 mg/kg 9NC, the maximum concentration for 9NC was 19.1 ng/ml at 0.7 h with a half-life of 6.4 h and an AUC of 186 ng.h/ml. The maximum concentration of 9AC in this dog was 9.2 ng/ml at 2.9 h with an AUC of 310 ng.h/ml and a half-life of 21.1 h. The maximum concentration of 9NC in the mouse after a single oral dose of 4.1 mg/kg of 9NC was 732 ng/ml at time 0.1 h with an AUC of 441 ng.h/ml and a half-life of 10.0 h. The maximum concentration of 9AC in the mouse was 26 ng/ml at 0.6 h. The AUC was 63 ng.h/ml, and the half-life was 1.2 h. Incubation of mouse liver, spleen, kidney, brain, and muscle tissue with 9NC all indicated conversion to 9AC, yet no conversion was observable in cell-free plasma from human or mouse blood. Structural identification of 9AC was confirmed by mass spectrometry.
Seismic Risk Assessment of Unreinforced Brick Masonry Buildings System of Northern Pakistan (2009)

ii This research work was aimed at assessing the seismic risk of unreinforced brick masonry buildings’ system of Northern Pakistan, constructed in stone dust mortar. To accomplish this, four series of unreinforced brick masonry piers constructed in stone dust mortar were tested in the in-plane direction using quasi-static method of testing. Each pier series comprised of three piers with identical properties and thus a total of twelve piers were tested. Aspect ratio and pre-compression were kept as the main variables. Various properties such as displacement ductility factors, ultimate drift ratios, coefficient of equivalent viscous damping, stiffness degradation and modulus of rigidity were determined using the experimental data from quasi-static cyclic tests on the piers. The effect of pre-compression on the coefficient of equivalent viscous damping and stiffness degradation were studied. Similarly, the effect of drift ratio on the coefficient of equivalent viscous damping was also studied. Various performance levels for unreinforced brick masonry piers, in relation to drift ratios, were also recommended. Based on the results of experimental work, a methodology was proposed for lateral strength assessment of unreinforced brick masonry buildings. The developed methodology produced
In silico identification of vaccine targets for 2019-nCoV (Data tables) (2020)

<strong>Background</strong> The newly identified coronavirus known as 2019-nCoV has posed a serious global health threat. According to the latest report (18-February-2020), it has infected more than 72,000 people globally and led to deaths of more than 1,016 people in China. <strong>Methods</strong> The 2019 novel coronavirus proteome was aligned to a curated database of viral immunogenic peptides. The immunogenicity of detected peptides and their binding potential to HLA alleles was predicted by immunogenicity predictive models and NetMHCpan 4.0. <strong>Results</strong> We report <em>in silico</em> identification of a comprehensive list of immunogenic peptides that can be used as potential targets for 2019 novel coronavirus (2019-nCoV) vaccine development. First, we found 28 nCoV peptides identical to Severe acute respiratory syndrome-related coronavirus (SARS CoV) that have previously been characterized immunogenic by T cell assays. Second, we identified 48 nCoV peptides having a high degree of similarity with immunogenic peptides deposited in The Immune Epitope Database (IEDB). Lastly, we conducted a <em>de novo</em> search of 2019-nCoV 9-mer peptides that i) bind to common HLA alleles in Chinese and European population and ii) have T Cell Receptor (TCR) recognition potential by positional weight matrices and a recently developed immunogenicity algorithm, iPred, and identified in total 63 peptides with a high immunogenicity potential. <strong>Conclusions</strong> Given the limited time and resources to develop vaccine and treatments for 2019-nCoV, our work provides a shortlist of candidates for experimental validation and thus can accelerate development pipeline.
Protein complexity of central nervous system cell lines (1986)

The total extracellular proteins and the most abundant 960 intracellular proteins of clonal CNS nerve and glial cell lines were examined by quantitative 2-dimensional acrylamide gel electrophoresis. While less than 0.2% of the intracellular proteins differ among the 5 nerve and 4 glial cell lines studied, over 65% of the extracellular proteins vary in distribution between the 2 major classes of CNS cells. These data indicate that the phenotypic complexity of nerve and glia populations is similar and that most of the protein complexity is in extracellular molecules.
Continuous curvature planning with obstacle avoidance capabilities in urban scenarios (2014)

This paper presents a continuous curvature planning algorithm with obstacle avoidance capabilities. The automated system generates a collision free path that considers vehicle's constraints, the road and different obstacles inside the horizon of view. The developed planning module was integrated in the RITS (former IMARA) autonomous vehicle architecture. The goal of this module is to obtain an accurate, continuous and safe path generation, by implementing parametric curves. To this end, a continuous curvature profile when calculating vehicle trajectory is introduced. It also permits to generate different speed profiles, improving the comfort by reducing lateral accelerations in the driving process. These algorithms have been implemented in simulated -ProSiVIC- and real platforms -Cybercars- showing good results in both cases. This approach is currently being implemented in the framework of the EU CityMobil2 project.
Molecular analysis of kanamycin and viomycin resistance in Mycobacterium smegmatis by use of the conjugation system (1997)

We examined the molecular mechanisms of resistance to kanamycin and viomycin in Mycobacterium smegmatis. All of the M. smegmatis strains with high-level kanamycin resistance had a nucleotide substitution from A to G at position 1389 of the 16S rRNA gene (rrs). This position is equivalent to position 1408 of Escherichia coli, and mutation at this position is known to cause aminoglycoside resistance. Mutations from G to A or G to T at position 1473 of the M. smegmatis rrs gene were found in viomycin-resistant mutants which had been designated vicB mutants in our earlier studies. Using the M. smegmatis conjugation system, we confirmed that these mutations indeed contributed to kanamycin and viomycin resistance, and kanamycin susceptibility was dominant over resistance in a heterogenomic strain. Additional experiments showed that three of four Mycobacterium tuberculosis strains with high-level kanamycin resistance had a mutation from A to G at position 1400, which was equivalent to position 1389 of M. smegmatis.
Imaging Membrane Potential Dynamics in Neurons (2012)

Neurons perform fast information processing in the form of membrane potential dynamics. Therefore, detailed examinations of membrane potential dynamics in neurons are crucial to the understanding of neuronal information processing and brain functions. However, attempts to characterize membrane potential dynamics in neurons have been hampered by the small size and the complexity of neurites, such as dendritic spines and axons, where conventional electrophysiological techniques have limited access. Furthermore, while optical imaging techniques provide better access to these structures, fluorescence-based imaging techniques are not suitable for quantitative membrane potential measurements. Second harmonic generation (SHG) imaging, which can overcome these problems, can be utilized for quantitative membrane potential imaging. Here, I review the basic principles and applications of SHG imaging in neuroscience researches and discuss the potential of this technique.
Isolation and characterization of monoclonal antibodies to structural and nonstructural herpesvirus saimiri proteins (1984)

An improved screening procedure was applied to identify hybridomas secreting antibodies to herpesvirus saimiri-specified polypeptides among the products of fusions between SP2/0 myeloma cells and spleen cells from mice immunized with purified virus particles or virus-specific DNA-binding proteins. Twenty-four monoclonal antibodies were isolated with specificities for 13 different virus-specified polypeptides (or complexes of polypeptides), including the major capsid protein of the virus (150K), the 160K and 130K structural proteins, a 108K structural phosphoprotein, structural glycoproteins, the nonstructural early 76K protein, early nonstructural DNA-binding proteins of 48 to 51K and 110K and the major immediate-early protein of 52K. Antibody to the virus 76K protein precipitated a host protein of 62K, and a number of antibodies specific for host proteins were also isolated. Antibody to the 52K immediate-early polypeptide precipitated the delayed-early 76K protein, whereas the antibody to the 76K protein did not precipitate the 52K polypeptide. These observations suggest the presence of epitopes common to virus and host proteins and an antigenic site common to an immediate-early and a delayed-early virus protein. The antibodies were used to examine the sites of intracellular accumulation of virus polypeptides, the formation of complexes of structural proteins, and the postsynthetic processing of virus proteins. The present collection of monoclonal antibodies provides a set of reagents with specificities for members of each of the major kinetically or functionally distinct classes of virus gene products.
SBVLC: Secure Barcode-Based Visible Light Communication for Smartphones (2015)

2D barcodes have enjoyed a significant penetration rate in mobile applications. This is largely due to the extremely low barrier to adoption-almost every camera-enabled smartphone can scan 2D barcodes. As an alternative to NFC technology, 2D barcodes have been increasingly used for security-sensitive mobile applications including mobile payments and personal identification. However, the security of barcode-based communication in mobile applications has not been systematically studied. Due to the visual nature, 2D barcodes are subject to eavesdropping when they are displayed on the smartphone screens. On the other hand, the fundamental design principles of 2D barcodes make it difficult to add security features. In this paper, we propose SBVLC-a secure system for barcode-based visible light communication (VLC) between smartphones. We formally analyze the security of SBVLC based on geometric models and propose physical security enhancement mechanisms for barcode communication by manipulating screen view angles and leveraging user-induced motions. We then develop three secure data exchange schemes that encode information in barcode streams. These schemes are useful in many security-sensitive mobile applications including private information sharing, secure device pairing, and contactless payment. SBVLC is evaluated through extensive experiments on both Android and iOS smartphones.
Thyrocyte-specific Gq/G11 deficiency impairs thyroid function and prevents goiter development (2007)

The function of the adult thyroid is regulated by thyroid-stimulating hormone (TSH), which acts through a G protein-coupled receptor. Overactivation of the TSH receptor results in hyperthyroidism and goiter. The Gs-mediated stimulation of adenylyl cyclase-dependent cAMP formation has been regarded as the principal intracellular signaling mechanism mediating the action of TSH. Here we show that the Gq/G11-mediated signaling pathway plays an unexpected and essential role in the regulation of thyroid function. Mice lacking the alpha subunits of Gq and G11 specifically in thyroid epithelial cells showed severely reduced iodine organification and thyroid hormone secretion in response to TSH, and many developed hypothyroidism within months after birth. In addition, thyrocyte-specific Galphaq/Galpha11-deficient mice lacked the normal proliferative thyroid response to TSH or goitrogenic diet, indicating an essential role of this pathway in the adaptive growth of the thyroid gland. Our data suggest that Gq/G11 and their downstream effectors are promising targets to interfere with increased thyroid function and growth.
The Gentleman From Louisiana (1934)

Essay| November 01 1934 The Gentleman From Louisiana F.Raymond Daniell* F.Raymond Daniell* *Mr. Daniell, a staff correspondent of The New York Times, has made several surveys of conditions in the South. Most recently he has been in Louisiana. Search for other works by this author on: This Site PubMed Google Scholar Current History (1934) 41 (2): 172–178. https://doi.org/10.1525/curh.1934.41.2.172 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation F.Raymond Daniell*; The Gentleman From Louisiana. Current History 1 November 1934; 41 (2): 172–178. doi: https://doi.org/10.1525/curh.1934.41.2.172 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentCurrent History Search This content is only available via PDF. © 1934 by The Regents of the University of California1934 Article PDF first page preview Close Modal You do not currently have access to this content.
Laser fusion project second annual report (1978)

This research program is devoted to the preparation and characterization of fluoride glasses for laser fusion. The overall objective is to explore and characterize fluoride glass systems to find a glass with the lowest possible nonlinear refractive index, satisfactory chemical durability, and physical properties which enable coating large optical quality pieces. (MOW)
Antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens (2011)

This study was conducted to evaluate the effect of aqueous, ethanolic and ethyl acetate extracts from neem leaves on growth of some human pathogens (Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus terreus, Candida albicans and Microsporum gypseum) in vitro. Different concentrations (5, 10, 15 and 20%) prepared from these extracts inhibited the growth of the test pathogens and the effect gradually increased with concentration. The 20% ethyl acetate extract gave the strongest inhibition compared with the activity obtained by the same concentration of the other extracts. High Performance Liquid Chromatography (HPLC) analysis of ethyl acetate extract showed the presence of a main component (nimonol) which was purified and chemically confirmed by Nuclear Magnetic Resonance (NMR) spectroscopic analysis. The 20% ethyl acetate extract lost a part of its antifungal effect after pooling out the nimonol and this loss in activity was variable on test pathogens. The purified nimonol as a separate compound did not show any antifungal activity when assayed against all the six fungal pathogens.
Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease (2014)

The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the continuous growing amount of papers and reviews, reflecting the important efforts made by scientists in this field. It is well known that AD is the most common cause of dementia, and up-to-date there is no prevention therapy and no cure for the disease, which contrasts with the enormous efforts put on the task. On the other hand many aspects of AD are currently debated or even unknown. This review offers a view of the current state of knowledge about AD which includes more relevant findings and processes that take part in the disease; it also shows more relevant past, present and future research on therapeutic drugs taking into account the new paradigm "Multi-Target-Directed Ligands" (MTDLs). In our opinion, this paradigm will lead from now on the research toward the discovery of better therapeutic solutions, not only in the case of AD but also in other complex diseases. This review highlights the strategies followed by now, and focuses other emerging targets that should be taken into account for the future development of new MTDLs. Thus, the path followed in this review goes from the pathology and the processes involved in AD to the strategies to consider in on-going and future researches.
Theories of personality (2nd ed.), Englewood Cliffs (Prentice-Hall, Inc) 1991, 428 p. (1991)

Our approach to the study of personality is to provide a thorough coverage of each of the major theories and to compare and integrate the various approaches. In deciding which theories to discuss, we have chosen those that have had the most significant impact on the field and that are of greatest current importance to our understanding of personality. We have attempted to write about each theory in such a way that the coverage is at once basic and advanced. An understanding of the theories presented requires no prior knowledge of personality theory, but at the same time, we provide sufficient comprehensive coverage of most theories to support advanced study of the theory and its ramifications. / Thus each theory chapter also discusses the historical origins of the theory and the biographical background of the major theorists, covers research associated with the theory, provides a critical evaluation of the approach, deals with applications of the theory, where relevant, and compares the theory with others. Index: Preface – I. Introduction – Theory and research in personality – II. Psychodynamic theories – Psychoanalytic theory: Sigmund Freud – Ego psychology: Erik H. Erikson and Heinz Hartmann – Analytical psychology: Carl Jung – Social analytic theory: Alfred Adler, Karen Horney, Erich FROMM, and Harry Stack Sullivan – III. Phenomenological-humanistic theory – Phenomenological-humanistic theory: Carl Rogers and Abraham Maslow – IV. Behavioral and cognitive approaches – Stimulus-response learning theory: John Dollard and Neal Miller – A behavioral approach: B. F. Skinner – Cognition, personality, and behavior: George Kelly – Social learning and cognition: Information processing theory: Albert Bandura, Walter Mischel, and Julian Rotter – V. Factor and typological theories – Structure-based systems theory: Raymond Cattell – A typological theory: Hans Jurgen Eysenck – VI. Field theory – Field theory: Kurt Lewin – VII. Integration and conclusion – An overview of personality theory – Glossary – Author index – Subject index.
Short-Term Changes of Hearing and Distortion Product Otoacoustic Emissions in Sudden Sensorineural Hearing Loss (2010)

Our findings showed that the function of outer hair cells is relatively spared in ears with the initial mild-to-moderate hearing loss, and its recovery is not related to the hearing improvement; however, the function of outer hair cells is impaired in ears with the initial moderately severe to profound hearing loss, and the functional improvement of outer hair cells is important for hearing recovery. Clinical implications of our findings were discussed.
GROUNDWATER RECHARGE AND QUALITY TRANSFORMATIONS DURING THE INITIATION AND MANAGEMENT OF A NEW STABILIZATION LAGOON (1973)

The objectives of an investigation at a new stabilization lagoon near Tucson, Arizona were 1) to estimate seepage losses; 2) to monitor the subsurface movement of seepage water and associated quality transformations; and 3) to compare the field data on nitrogen transformations with parallel data from a predictive computer model. Raw sewage was metered into the newly constructed lagoon. Seepage losses were calculated from data on inflow, evaporation, and change in storage of the lagoon. Water samples were obtained from depths of 40, 60 and 100 ft below the surface of the lagoon. The native groundwater table is 70 ft below the land surface in this area. Surface and subsurface water samples were examined for coliform organisms, plus various physical and chemical constituents. Estimated seepage rates from the lagoon ranged from 0.40 ft/day to 0.03 ft/day. A computer model was tested using the nitrate values obtained from the collected water samples. The model assumed that flow was entirely in the vertical direction and that the flow environment was aerobic. The actual nitrate values at 60 ft and values computed from the model were compared at the beginning of the inundation and after 69 days, with the results closely corresponding. No apparent undesirable effects occurred from seepage on the groundwater quality.