gebhart/patrepeval huggingface dataset:
Computerized vital signs analysis and late onset infections in extremely low gestational age infants (2016)

The RALIS algorithm is a sensitive indicator for early detection of infection in preterm infants. Further modifications to improve the specificity of the algorithm are needed prior to application of VS modeling to patient antibiotic treatment decisions.
Reactive Ion Etching of Benzocyclobutene Using a Silicon Nitride Dielectric Etch Mask (1995)

The feasibility of patterning a cured polymeric film of benzocyclobutene (BCB) using silicon nitride as an etch mask was investigated. Due to the carbon‐ and silicon‐containing composition of BCB, a gas mixture with oxygen‐ and fluorine‐containing components is required, which unfortunately also etches . Therefore, a reactive ion etching process with high selectivity between the etch rates of the BCB, CYCLOTENE™ 3022‐46, and the was developed. We have investigated the dependence of the etch rates as a function of the content in the gas mixture. The surface morphology and the angle of the etched BCB sidewall were determined using a scanning electron microscope. A process with content was defined, exhibiting etch rates of 155 and 14 nm/min for the polymerized BCB and the , respectively. This yields a selectivity of 11:1. The morphology of the etched BCB surface is smooth. Depending on the shape of the etch mask, sidewall angles of the BCB structure between 70° and 80° were obtained. These inclinations allow an effective deposition of a contact metallization. For further technological processing, a residual dielectric film can be left on the structure when the BCB layer is etched.
Validation of Endogenous Controls for Gene Expression Studies in Human Adipocytes and Preadipocytes (2001)

Quantitative gene expression protocols require adequate controls to monitor intersample variation. Quantitative approaches to describe relative changes in gene expression use endogenous controls--"housekeeping" genes. Given the low amounts of mRNA in fat cells, RT-PCR is the method of choice, and housekeeping genes are widely used as endogenous controls. However, literature reports suggest changes in gene expression of typical housekeeping genes (e. g. GAPDH, beta-actin, 18S rRNA) upon hormonal stimulation or during adipogenic differentiation. Thus, we tested the influence of 6 hormones and adipogenic differentiation on gene expression levels of 11 commonly used housekeeping genes in primary cultured mature human adipocytes and preadipocytes. Using the TaqMan RT-PCR technique and "Human Endogenous Control Assays" (PE Biosystems), we found several housekeeping genes with at least twice the difference in expression levels between stimulated and unstimulated cells (such as acidic ribosomal protein, beta-actin, beta(2)-microglobulin and beta-glucuronidase). Only GAPDH and transferrin receptor gene expression levels did not change under any of the stimuli tested, thus appeared best suited for gene expression studies in human adipose cells across a wide range of experimental settings.
Implementing the Model (1972)

This article restates briefly the design of the model developed by PSSAS and outlines in considerable detail the components of the program to prepare secondary school principals in terms of structure, content, personnel, and activity.
A paradigm shift: Cancer therapy with peptide-based B-cell epitopes and peptide immunotherapeutics targeting multiple solid tumor types: Emerging concepts and validation of combination immunotherapy (2015)

There is a recognizable and urgent need to speed the development and application of novel, more efficacious anti-cancer vaccine therapies that inhibit tumor progression and prevent acquisition of tumor resistance. We have created and established a portfolio of validated peptide epitopes against multiple receptor tyrosine kinases and we have identified the most biologically effective combinations of EGFR (HER-1), HER-2, HER-3, VEGF and IGF-1R peptide vaccines/mimics to selectively inhibit multiple receptors and signaling pathways. The strategy is based on the use of chimeric conformational B-cell epitope peptides incorporating "promiscuous" T-cell epitopes that afford the possibility of generating an enduring immune response, eliciting protein-reactive high-affinity anti-peptide antibodies as potential vaccines and peptide mimics that act as antagonists to receptor signaling that drive cancer metastasis. In this review we will summarize our ongoing studies based on the development of combinatorial immunotherapeutic strategies that act synergistically to enhance immune-mediated tumor killing aimed at addressing mechanisms of tumor resistance for several tumor types.
An Occlusion Approach with Consistency Constraint for Multiscopic Depth Extraction (2010)

This is a new approach to handle occlusions in stereovision algorithms in the multiview context using images destined for autostereoscopic displays. It takes advantage of information from all views and ensures the consistency of their disparity maps. We demonstrate its application in a correlation-based method and a graphcuts-based method. The latter uses a new energy, which merges both dissimilarities and occlusions evaluations. We discuss the results on real and virtual images.
Critical review of electrochemical advanced oxidation processes for water treatment applications (2014)

Electrochemical advanced oxidation processes (EAOPs) have emerged as novel water treatment technologies for the elimination of a broad-range of organic contaminants. Considerable validation of this technology has been performed at both the bench-scale and pilot-scale, which has been facilitated by the development of stable electrode materials that efficiently generate high yields of hydroxyl radicals (OH˙) (e.g., boron-doped diamond (BDD), doped-SnO2, PbO2, and substoichiometic- and doped-TiO2). Although a promising new technology, the mechanisms involved in the oxidation of organic compounds during EAOPs and the corresponding environmental impacts of their use have not been fully addressed. In order to unify the state of knowledge, identify research gaps, and stimulate new research in these areas, this review critically analyses published research pertaining to EAOPs. Specific topics covered in this review include (1) EAOP electrode types, (2) oxidation pathways of select classes of contaminants, (3) rate limitations in applied settings, and (4) long-term sustainability. Key challenges facing EAOP technologies are related to toxic byproduct formation (e.g., ClO4(-) and halogenated organic compounds) and low electro-active surface areas. These challenges must be addressed in future research in order for EAOPs to realize their full potential for water treatment.
The Gmicro/300 32-bit microprocessor (1990)

A high-end microprocessor, the Gmicro/300, based on the TRON architecture specification is described. In contrast to other RISC (reduced-instruction-set-computer) or CISC (complex-instruction-set-computer) chips, it executes an instruction with a memory operand and a register operand in one clock cycle. Separate cache memories improve performance more than 13.8%. The Gmicro/300's pipeline structure, its other one-cycle structures, and the effects of using internal caches are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Respiratory self‐navigation for whole‐heart bright‐blood coronary MRI: Methods for robust isolation and automatic segmentation of the blood pool (2011)

Free-breathing three-dimensional whole-heart coronary MRI is a noninvasive alternative to X-ray coronary angiography. However, the existing navigator-gated approaches do not meet the requirements of clinical practice, as they perform with suboptimal accuracy and require prolonged acquisition times. Self-navigated techniques, applied to bright-blood imaging sequences, promise to detect the position of the blood pool directly in the readouts acquired for imaging. Hence, the respiratory displacement of the heart can be calculated and used for motion correction with high accuracy and 100% scan efficiency. However, additional bright signal from the chest wall, spine, arms, and liver can render the isolation of the blood pool impossible. In this work, an innovative method based on a targeted combination of the output signals of an anterior phased-array surface coil is implemented to efficiently suppress such additional bright signal. Furthermore, an algorithm for the automatic segmentation of the blood pool is proposed. Robust self-navigation is achieved by cross-correlation. These improvements were integrated into a three-dimensional radial whole-heart coronary MRI sequence and were compared with navigator-gated imaging in vivo. Self-navigation was successful in all cases and the acquisition time was reduced up to 63%. Equivalent or slightly superior image quality, vessel length, and sharpness were achieved.
Comparing Statistical and Machine Learning Classifiers: Alternatives for Predictive Modeling in Human Factors Research (2003)

Multivariate classification models play an increasingly important role in human factors research. In the past, these models have been based primarily on discriminant analysis and logistic regression. Models developed from machine learning research offer the human factors professional a viable alternative to these traditional statistical classification methods. To illustrate this point, two machine learning approaches--genetic programming and decision tree induction--were used to construct classification models designed to predict whether or not a student truck driver would pass his or her commercial driver license (CDL) examination. The models were developed and validated using the curriculum scores and CDL exam performances of 37 student truck drivers who had completed a 320-hr driver training course. Results indicated that the machine learning classification models were superior to discriminant analysis and logistic regression in terms of predictive accuracy. Actual or potential applications of this research include the creation of models that more accurately predict human performance outcomes.
Occurrence of apple leaf rollers (Lepidoptera: Tortricidae) and their parasites in the Okanagan Valley, British Columbia. (1974)

Volume: 71
Digital design with minimal number of scan flip-flops (2002)

In this paper we present an efficient algorithm for the selection of flip-flops for partial scan design. The emphasis of the research is not on finding the (Minimum Feedback Vertex Set) MFVS set that makes the circuit acyclic, but rather a minimal set of vertices that opens long feedback loops while keeping the fault coverage within user-defined acceptable limit. The algorithm determines the vertex set to open loops of length K or higher. We applied the algorithm to several ISCAS-89 benchmark circuits. For K=1 and except for one circuit, the number of flip-flops to be scanned is the same or slightly higher than the previously published results. However as K increases, our results indicated that it is not necessary to determine the MFVS, since a reduction of the hardware overhead by about 50% corresponds to a fault coverage reduction of only 2% from its value for K=1.
Integrity = validity + completeness (1989)

Database integrity has two complementary components: validity , which guarantees that all false information is excluded from the database, and completeness , which guarantees that all true information is included in the database. This article describes a uniform model of integrity for relational databases, that considers both validity and completeness. To a large degree, this model subsumes the prevailing model of integrity (i.e., integrity constraints). One of the features of the new model is the determination of the integrity of answers issued by the database system in response to user queries. To users, answers that are accompanied with such detailed certifications of their integrity are more meaningful. First, the model is defined and discussed. Then, a specific mechanism is described that implements this model. With this mechanism, the determination of the integrity of an answer is a process analogous to the determination of the answer itself.
Acetylene (2000)

The article contains sections titled: 1. Introduction 2. Physical Properties 3. Chemical Properties 3.1. Industrially Important Reactions 3.2. Other Reactions; Derivatives 4. Production 4.1. Thermodynamic and Kinetic Aspects 4.2. Partial Combustion Processes 4.2.1. BASF Process (Sachsse-Bartholome) 4.2.2. Other Partial Combustion Processes 4.2.3. Submerged Flame Process 4.2.4. Partial Combustion Carbide Process 4.3. Electrothermic Processes 4.3.1. Production from Gaseous and/or Gasified Hydrocarbons (Hüls Arc Process) 4.3.2. Production from Liquid Hydrocarbons (Plasma Arc Process) 4.3.3. Production from Coal (Arc Coal Process) 4.3.4. Production from Calcium Carbide 4.3.4.1. Wet Generators 4.3.4.2. Dry Generators 4.3.4.3. Acetylene Purification 4.4. Other Cracking Processes 4.4.1. Thermal Cracking By Heat Carriers 4.4.2. Acetylene as a Byproduct of Steam Cracking 5. Safety Precautions, Transportation, and Storage 5.1. General Safety Factors and Safety Measures 5.2. Acetylene Storage in Cylinders 6. Uses and Economic Aspects 6.1. Use in Metal Processing 6.2. Use as Raw Material in Chemical Industry 6.3. Competitive Position of Acetylene as Chemical Feedstock 7. Propyne 8. Toxicology and Occupational Health
Novel Four-Wave Mixing Phenomenon in a Raman Amplifier (1995)

We report on an investigation of second Stokes generation in a Raman amplifier, during which we observed a pattern of narrow, approximately radial lines in the second Stokes far-field distribution. This previously unreported phenomenon, and other features in the far field, can be explained by a combination of diffuse scattering and four-wave mixing.
Demonstration of a switched resonator concept in a dual-band monolithic CMOS LC-tuned VCO (2002)

A switched resonator concept which allows better trade-off between phase noise and power consumption is demonstrated using a dual band VCO. The dual-band VCO operates near 900 MHz and 1.8 GHz with phase noise of -125 and 123 dBc/Hz at a 600-KHz offset and 16-mW power consumption. Compared to a single band 1.8 GHz VCO, the dual-band VCO has almost the same phase noise and power consumption.
Epigenetic Inheritance of Active Chromatin After Removal of the Main Transactivator (1999)

The Drosophila Polycomb and trithorax group proteins act through chromosomal elements such as Fab-7 to maintain repressed or active gene expression, respectively. A Fab-7 element is switched from a silenced to a mitotically heritable active state by an embryonic pulse of transcription. Here, histone H4 hyperacetylation was found to be associated with Fab-7 after activation, suggesting that H4 hyperacetylation may be a heritable epigenetic tag of the activated element. Activated Fab-7 enables transcription of a gene even after withdrawal of the primary transcription factor. This feature may allow epigenetic maintenance of active states of developmental genes after decay of their early embryonic regulators.
Capacitive Sensing 3D-printed Wristband for Enriched Hand Gesture Recognition (2017)

In this work, we design a wearable-form hand gesture recognition system using capacitive sensing technique. Our proposed system includes a 3D printed wristband, capacitive sensors arrays in a flexible circuit board, a low-cost micro-controller unit and wireless communication module (BLE). In particular, the wristband manipulates the changes in capacitance from multiple capacitive sensors to recognize and detect users' hand gestures. The software stack translates the detected gestures into control command for application layer, together with an user-friendly web interface that supports both data communication and training between the wristband and the host PC. We also release an open API of our designed system for future applications. Lastly, we envision our system open API will be available for developers to customize vast range of hand gesture and integrate the wristband into various applications, from command on remote computer to video game controller.
Signaling Analysis for Multi-Radio Management (2009)

Increasing bandwidth demand from mobile Internet applications and the existence of 2G, 3G and soon 4G equipment in operators' networks forces them to implement an efficient resource management over all available radio access technologies. While such a multi-radio management will certainly improve resource utilization and allows reducing local hot spots, it comes at the cost of additional signaling load. In this work, we present an analysis of the signaling requirements of a multi-radio management in the fixed part of an operator's network. The signaling load for multi-radio access selection in different system architectures and for different signaling concepts is evaluated, quantified and compared. This analysis permits to conclude on the best-suited implementation strategy for co-located GSM, UMTS and LTE networks.
Ca2+-dependent Interaction of Recoverin with Rhodopsin Kinase (1995)

Recoverin (Rv) is a myristoylated Ca(2+)-binding protein present primarily in bovine photoreceptors. It represents a newly identified family of neuronal specific Ca(2+)-binding proteins that includes neurocalcin, hippocalcin, and guanylyl cyclase-activating protein. To investigate the function of Rv in photoreceptors, we identified proteins that bind immobilized Rv in a Ca(2+)-dependent manner. Rhodopsin kinase (RK), interphotoreceptor retinoid-binding protein, and tubulin interact with Rv in the presence of Ca2+. The importance of the Rv/RK interaction was further characterized. RK, purified using immobilized Rv as an affinity matrix, catalyzed the light-dependent and Ca(2+)-independent incorporation of phosphates into rhodopsin when reconstituted with urea-stripped rod outer segment membranes. When only a small fraction (0.04%) of rhodopsin was photolyzed, as many as 700 phosphates were incorporated per photolyzed rhodopsin, a phenomenon known as "high gain" phosphorylation. When recoverin was added, the activity of RK became sensitive to free Ca2+, with EC50 = 3 microM. The N-terminal myristoyl residue of Rv enhances the inhibitory effect of Rv and introduces cooperativity to the Ca(2+)-dependent inhibition of rhodopsin phosphorylation. Rv neither interacts with other members of the G-protein-coupled receptor kinase family such as beta-adrenergic receptor kinase 1 nor inhibits beta-adrenergic receptor kinase 1 activity. The specific and Ca(2+)-dependent Rv/RK interaction is necessary for the inhibitory effect of Rv on rhodopsin phosphorylation and may play an important role in photoreceptor light adaptation.
Loss of Editing Activity during the Evolution of Mitochondrial Phenylalanyl-tRNA Synthetase (2005)

Accurate selection of amino acids is essential for faithful translation of the genetic code. Errors during amino acid selection are usually corrected by the editing activity of aminoacyl-tRNA synthetases such as phenylalanyl-tRNA synthetases (PheRS), which edit misactivated tyrosine. Comparison of cytosolic and mitochondrial PheRS from the yeast Saccharomyces cerevisiae suggested that the organellar protein might lack the editing activity. Yeast cytosolic PheRS was found to contain an editing site, which upon disruption abolished both cis and trans editing of Tyr-tRNA(Phe). Wild-type mitochondrial PheRS lacked cis and trans editing and could synthesize Tyr-tRNA(Phe), an activity enhanced in active site variants with improved tyrosine recognition. Possible trans editing was investigated in isolated mitochondrial extracts, but no such activity was detected. These data indicate that the mitochondrial protein synthesis machinery lacks the tyrosine proofreading activity characteristic of cytosolic translation. This difference between the mitochondria and the cytosol suggests that either organellar protein synthesis quality control is focused on another step or that translation in this compartment is inherently less accurate than in the cytosol.
High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress (2011)

HMGB1 is important for oxidative stress-mediated autophagy and serves as a new target for the treatment of stress-associated disorders.
6DOF iterative closest point matching considering a priori with maximum a posteriori estimation (2013)

We present a new matching algorithm considering a priori (the prior probability) based on Bayes' theorem. Performance of point cloud registration between target and source clouds is effectively improved by introducing maximum a posteriori (MAP) estimation. The standard Iterative Closest Point (ICP) algorithm for the registration sometimes falls into misalignment due to measurement errors, narrow sensing field of view, or the movement of objects during measurement. Our approach resolves such problems by considering both the likelihood of the measurement and the prior probability of the initial guess for registration in the objective function. We have implemented a new 6DOF Iterative Closest Point matching using MAP estimation, and evaluated the method in real environments comparing with conventional registration methods. The experimental results have shown that our proposed method has wide convergence region and matches point clouds accurately preventing the misalignment problem.
Lipophilized Epigallocatechin Gallate (EGCG) Derivatives as Novel Antioxidants (2011)

Epigallocatechin gallate (EGCG) is the major polyphenol in green tea and known to render many health benefits associated with tea consumption. EGCG was modified structurally to improve its lipophilicity, expand its application in lipophilic media, and enhance its cellular absorption in vivo. Esterification of the water-soluble EGCG with selected long-chain saturated and unsaturated fatty acids was carried out, followed by a purification process. Ester derivatives of EGCG with stearic acid (SA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) were prepared, and their enhanced lipophilicity was confirmed by octanol-water partition coefficient. The chemical structures of the EGCG derivatives, determined by HPLC-MS and ¹H and ¹³C NMR, were EGCG-3',5',3'',5''-O-tetraesters of SA, EPA, and DHA. The lipophilized EGCG derivatives exhibited greater antioxidant activity in scavenging the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical than EGCG itself. The results suggest that EGCG derivatives may be used as potential lipophilic antioxidants in the food, cosmetic, and medicinal industries.
Power assist method for HAL-3 using EMG-based feedback controller (2004)

We have developed the exoskeletal robotics suite HAL (Hybrid Assistive Leg) which is integrated with human and assists suitable power for lower limb of people with gait disorder. This study proposes the method of assist motion and assist torque to realize a power assist corresponding to the operator's intention. In the method of assist motion, we adopted Phase Sequence control which generates a series of assist motions by transiting some simple basic motions called Phase. We used the feedback controller to adjust the assist torque to maintain myoelectricity signals which were generated while performing the power assist walking. The experiment results showed the effective power assist according to operator's intention by using these control, methods.