gebhart/patrepeval huggingface dataset:
Digital quasi-random modulated SFAVM PWM in an AC-drive system (1994)

A main research topic in PWM-VSI inverter-driven electrical machines is to reduce the generated acoustic noise which often is dominated by a multiple of the switching frequency in the inverter. This paper proposes a modulation scheme for reducing the acoustic noise effect from an AC machine which can be implemented digitally for low and high performance systems. The scheme is based on a stator flux asynchronous vector modulation (SFAVM) imposed by a digital band limited PWM white noise generator for varying the switching frequency randomly. The white noise generator can be used for 8, 16 and 32 bit microcontrollers. The modulation strategy is tested in a 1 kVA high performance 16 bit microprocessor controlled AC drive system. Voltage-spectra on the line-to-line voltage and the acoustic noise spectra are presented and show that the new modulation strategy can decrease the noise effect. The stator-flux-polygon and the line current are measured and demonstrate the random modulation strategy. Finally, the total sound pressure level from the AC machine is investigated with fixed switching frequencies and with different randomly modulated frequency spans. It is concluded that a properly chosen fixed switching frequency has the lowest total sound pressure level. However, the random modulation strategy distributes the noise frequencies and the noise is more comfortable and less annoying.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Growth Inhibition of Human Non-Small Lung Cancer Cells H460 By Green Tea and Ginger Polyphenols (2012)

The study reports the antiproliferative and apoptosis-mediated cytotoxic effects of green tea and ginger polyphenolic extracts on human H460 cell line, indicating their promising chemopreventive effect against lung cancer.
Reconstructing Synthetic Profiles from Surface Data (2004)

A method for the extrapolation of vertical profiles of temperature (and/or steric heights) from measurements of sea surface elevation and sea surface temperature has been developed and is described here. The technique, called coupled pattern reconstruction (CPR), is based on a multivariate analysis of the coupled variability of vertical profiles from historical hydrographic data and on the hypothesis that only few modes are needed to explain most of the covariance of the fields. Through a linear regression between the amplitudes of the coupled modes it is possible to reconstruct the first two modes by solving a simple linear system written for the surface values, which are supposed to be known. The CPR method has been applied and tested on 9 yr of conductivity– temperature–depth (CTD) measurements collected in the northern Mediterranean Sea during the Dynamiques des Flux de Matière en Mediterranée (DYFAMED) program (1994–2002). The first 6 yr were used as a training dataset, while the last 3 were set aside as independent test measurements. Results have demonstrated a substantial improvement in terms of absolute error with respect to an ad hoc climatology, and slightly worse performances compared to the most advanced technique found in literature, which consists of the single empirical orthogonal function reconstruction (sEOF-R) through a multivariate regression of the amplitudes, except for the very first meters. However, CPR is demonstrated to be much more robust and better performing with respect to sEOF-R when considering the errors associated with real measurements of sea surface elevation.
Transmit Correlation-aided Scheduling in Multiuser MIMO Networks (2006)

The problem of joint scheduling and beamforming for a multiuser multiple-input multiple-output (MIMO) network with partial channel state information at the transmitter (CSIT) is addressed here. Unlike most previous work that rely on full instantaneous CSIT and require unacceptable overhead feedback to the transmitter, we point out here that useful information relevant to the scheduler lies untapped in the long term statistical information of the user's channels. We show how statistical CSIT can be efficiently combined with partial instantaneous CSIT to derive a scheduling rule for the downlink of multiuser MIMO systems
Solving symmetric and asymmetric TSPs by ant colonies (2002)

We present ACS, a distributed algorithm for the solution of combinatorial optimization problems which was inspired by the observation of real colonies of ants. We apply ACS to both symmetric and asymmetric traveling salesman problems. Results show that ACS is able to find good solutions to these problems.
Attenuation of Cellular Inflammation Using Glucocorticoid-Functionalized Copolymers (2007)

This work has demonstrated the functionalization of an amphiphilic diblock copolymer, comprised of polyethylene oxide-polymethyl methacrylate (PEO-PMMA), as well as a triblock copolymer comprised of polymethyloxazoline-polydimethylsiloxane-polymethyloxazoline(PMOXA-PDMS-PM OXA) with the dexamethasone (Dex) glucocorticoid anti-inflammatory. Interfacial deposition of the copolymer and the Dex molecules and subsequent transfer of the hybrid materials to solid substrates were characterized to evaluate the potential of utilizing this composite material as a suppressor of cyto-inflammation to enhance implant biocompatibility. Given the extremely thin dimensions of the film (~4nm), this material would have negligible impact upon the size of the coated device to preclude biological stress. The composite films were interfaced with the RAW264.7 murine macrophages which served as a model cell line for the evaluation of nuclear factor-kappaB (NF-KB)-induced production of a host of inflammatory cytokines including interleukin-6, interleukin-12, tumor necrosis factor-alpha (TNFalpha), as well as the inducible nitric oxide synthase signaling factor which is known to be involved with stress-related processes such as neuronal damage. Lipopolysaccharide or LPS is a component of bacterial membranes that elicits cellular stress following application to RAW cell cultures. Following the induced stress response, significant reductions in the expression of genes associated with the aforementioned cytokines and signaling molecules indicated that macrophages in direct contact with the functionalized copolymer were able to collect Dex that was released from within the polymer network to attenuate cyto-inflammation mechanisms. This composite membrane represents a medically-relevant technology to promote chronic implant functionality and preclusion of bio-fouling.
A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening (2015)

Demethylation of histones by lysine demethylases (KDMs) plays a critical role in controlling gene transcription. Aberrant demethylation may play a causal role in diseases such as cancer. Despite the biological significance of these enzymes, there are limited assay technologies for study of KDMs and few quality chemical probes available to interrogate their biology. In this report, we demonstrate the utility of self-assembled monolayer desorption/ionization (SAMDI) mass spectrometry for the investigation of quantitative KDM enzyme kinetics and for high-throughput screening for KDM inhibitors. SAMDI can be performed in 384-well format and rapidly allows reaction components to be purified prior to injection into a mass spectrometer, without a throughput-limiting liquid chromatography step. We developed sensitive and robust assays for KDM1A (LSD1, AOF2) and KDM4C (JMJD2C, GASC1) and screened 13,824 compounds against each enzyme. Hits were rapidly triaged using a redox assay to identify compounds that interfered with the catalytic oxidation chemistry used by the KDMs for the demethylation reaction. We find that overall this high-throughput mass spectrometry platform coupled with the elimination of redox active compounds leads to a hit rate that is manageable for follow-up work.
A Full-range All-pass Variable Phase Shifter for Multiple Antenna Receivers (2005)

A fourth-order all-pass variable phase shifter achieves a total phase shift range greater than 360/spl deg/ in a 10.35-10.8 GHz band of frequencies for multiple-antenna receiver applications. A cascode biasing technique is used to halve power consumption compared to conventional approaches and the variable phase shifter is optimized using a parasitic-aware particle-swarm optimization paradigm. Simulation results show power gain of 1.4/spl plusmn/0.7 dB, return loss less than -15 dB and minimum IIP3 of -3 dBm in a 250 nm SiGe HBT process.
Experimental Determination of Conduction and Valence Bands of Semiconductor Nanoparticles using Kelvin Probe Force Microscopy (2012)

The ability to determine a semiconductor’s band edge positions is important for the design of new photocatalyst materials. In this paper, we introduced an experimental method based on Kelvin probe force microscopy to determine the conduction and valence band edge energies of semiconductor nanomaterials, which has rarely been demonstrated. We tested the method on six semiconductor nanoparticles (α-Fe2O3, CeO2, Al2O3, CuO, TiO2, and ZnO) with known electronic structures. The experimentally determined band edge positions for α-Fe2O3, Al2O3, and CuO well matched the literature values with no statistical difference. Except CeO2, all other metal oxides had a consistent upward bias in the experimental measurements of band edge positions because of the shielding effect of the adsorbed surface water layer. This experimental approach may outstand as a unique alternative way of probing the band edge energy positions of semiconductor materials to complement the current computational methods, which often find limitations in new synthetic or complex materials. Ultimately, this work provides scientific foundation for developing experimental tools to probe nanoscale electronic properties of photocatalytic materials, which will drive breakthroughs in the design of novel photocatalytic systems and advance the fundamental understanding of material properties.
The combination of dissimilar alleles of the A alpha and A beta gene complexes, whose proteins contain homeo domain motifs, determines sexual development in the mushroom Coprinus cinereus. (1992)

The A mating-type factor is one of two gene complexes that allows mating cells of the mushroom Coprinus cinereus to recognize self from nonself and to regulate a pathway of sexual development that leads to meiosis and sporulation. We have identified seven A genes separated into two subcomplexes corresponding to the classical A alpha and A beta loci. Four genes, one alpha and three beta, all coding for proteins with a homeo domain-related motif, determine A-factor specificity; their allelic forms are so different in sequence that they do not cross-hybridize. It requires only one of these four genes to be heteroallelic in a cell to trigger A-regulated sexual development, and it is the different combinations of their alleles that generate the multiple A factors found in nature. The other three genes cause no change in cell morphology and may regulate the activity of the four specificity genes.
Underbalanced drilling benefits now available offshore (1997)

Offshore underbalanced drilling (UBD) is a reality. Applications in older, partially depleted fields and new fields are being considered. However, low productivity reservoirs and fields with sub normal pressures causing drilling problems are currently the main targets for offshore UBD. With proper planning and the correct technique, both jointed pipe and coiled tubing UBD drilling operations have been carried out offshore with success. The main concerns for offshore UBD have been altered drilling practices and surface production system operation. These issues have been examined and equipment has been designed and tested to address them. Environmental, safety and health issues are paramount and have been studied carefully. Detailed well planning, engineering, and flow modeling have proven critical for successful offshore UBD operations. Examples are given from oil and gas fields.
First-principles studies of the intrinsic effect of nitrogen atoms on reduction in gate leakage current through Hf-based high-k dielectrics (2005)

The atomistic effects of N atoms on the leakage current through HfO2 high-k gate dielectrics have been studied from first-principles calculations within the framework of a generalized gradient approximation (GGA). It has been found that the intrinsic effects of N atoms drastically reduce the electron leakage current. N atoms couple favorably with oxygen vacancies (VO) in HfO2 and extract electrons from VO. As a result, VO energy levels are drastically elevated due to the charged-state change in VO from neutral (VO0) to positively charged (VO2+). Accordingly, N incorporation removes the electron leakage path mediated by VO related gap states.
Unconstrained face verification using deep CNN features (2016)

In this paper, we present an algorithm for unconstrained face verification based on deep convolutional features and evaluate it on the newly released IARPA Janus Benchmark A (IJB-A) dataset as well as on the traditional Labeled Face in the Wild (LFW) dataset. The IJB-A dataset includes real-world unconstrained faces from 500 subjects with full pose and illumination variations which are much harder than the LFW and Youtube Face (YTF) datasets. The deep convolutional neural network (DCNN) is trained using the CASIA-WebFace dataset. Results of experimental evaluations on the IJB-A and the LFW datasets are provided.
Overview of Efficient Vibroseis Acquisition Methods (2006)

Many methods have been developed in the past 25 years to speed up Vibroseis acquisition. I give an overview of the most promising ones and propose a classification of them in three categories: simultaneous shooting, cascaded sweeps and slip sweeps. The main features of these methods are summarized and some criteria for the selection of the most suitable are introduced.
An improved ADC method for vibration control (2011)

In this paper a Hexapod Platform was researched for application in the field of vibration control. While using traditional ADC method to control the platform to isolate vibration, the result tends to be emanative for some specified vibration signals. After analyzing this phenomenon and doing some simulations, a result was presented that the reference signal in ADC Method has a phase deviation from what is really needed. In addition, an improved ADC method was explored by conducting a filter module according to system identification, which can compensate the phase deviation. The experiment shows that the improved ADC method is available to achieve a convergent result for those specified vibration signals, and the vibration magnitude is reduced by about 90%.
Responses of young and aged rat CNS to partial cholinergic immunolesions and NGF treatment (1998)

The cholinergic neurons of the basal forebrain (CNBF) are the major source of cholinergic innervation of the cortex and hippocampus. In Alzheimer's disease and aged brain, there are severe losses of cholinergic neurons in the nucleus basalis of Meynert, leading to a reduction of cortical cholinergic activity which correlates with the severity of cognitive deficits. While there is evidence that aged central nervous system (CNS) displays impaired stress response signaling, pharmacologic treatments with neurotrophic factors appear to ameliorate these age-associated cholinergic deficits. To mimic these cholinergic deficits in experimental animals and study the acute effects of nerve growth factor (NGF), we induced a partial lesion of CBFNs by the intracerebroventricular (icv) injection of the cholinergic immunotoxin 192IgG-saporin, in groups of 3- and 30-month-old rats. The lesion was followed 14 days later by icv administration of NGF, known to restore partial immunolesion-induced cholinergic deficits in rat CNS, and all rats were killed 2 days after the NGF treatement. Here we report the effects of partial immunolesions on the levels of choline acetyltransferase (ChAT) activity and NGF receptor mRNA levels in the basal forebrain of 3- and 30-month-old rats. Because of their presence in the promoters of the NGF, NGF receptors, and ChAT genes, we also measured DNA-binding activity of the transcription factors NFB and AP-1 in the cortex and hippocampus. We discuss these findings in the context of endogenous NGF-mediated signal transduction mechanisms and conclude that we have evidence for age-associated decreases in endogenous NGF responses to partial deafferentation of the basal forebrain cholinergic projections. J. Neurosci. Res. 52:322–333, 1998. © 1998 Wiley-Liss, Inc.
Sequencing-Based Detection of Low-Frequency Human Immunodeficiency Virus Type 1 Drug-Resistant Mutants by an RNA/DNA Heteroduplex Generator-Tracking Assay (2004)

Drug-resistant viruses may be present as minority variants during early treatment failures or following discontinuation of failed antiretroviral regimens. A limitation of the traditional direct PCR population sequencing method is its inability to detect human immunodeficiency virus type 1 (HIV-1) variants present at frequencies lower than 20%. A drug resistance genotyping assay based on the isolation and DNA sequencing of minority HIV protease variants is presented here. A multiple-codon-specific heteroduplex generator probe was constructed to improve the separation of HIV protease genes varying in sequence at 12 codons associated with resistance to protease inhibitors. Using an RNA molecule as probe allowed the simple sequencing of protease variants isolated as RNA/DNA heteroduplexes with different electrophoretic mobilities. The protease gene RNA heteroduplex generator-tracking assay (RNA-HTA) was tested on plasma quasispecies from 21 HIV-1-infected persons in whom one or more protease resistance mutations emerged during therapy or following initiation of salvage regimens. In 11 of 21 cases, RNA-HTA testing of virus from the first episode of virologic failure identified protease resistance mutations not seen by population-based PCR sequencing. In 8 of these 11 cases, all of the low-frequency drug resistance mutations detected exclusively by RNA-HTA during the first episode became detectable by population-based PCR sequencing at the later time point. Distinct sets of protease mutations could be linked on different genomes in patients with high-frequency protease gene lineages. The enhanced detection of minority drug resistance variants using a sequencing-based assay may improve the efficacy of genotype-assisted salvage therapies.
An information visualisation system for the understanding of web data (2008)

Internet has become one of the best communication and marketing tools. Hence, designing well-structured Web sites with the information or products that users look for is a crucial mission. For this reason, understanding Web data is a decisive task to assure the success of a Website. In that sense, data mining techniques provide many metrics and statistics useful to automatically discover the structure, contents and usage of a site. This research aims at proving the usefulness of a set of information visualisation techniques in order to analyse Web data, using a visual Web mining tool that allows the combination, coordination and exploration of visualisations to get insight on Web data. The tool, named WET, provides a set of visual metaphors that represent the structure of the Websites where Web metrics are overlaid.
Translational Blockade Imposed by Cytokine-Derived UA-Rich Sequences (1989)

The messenger RNAs specifying certain proteins involved in the inflammatory response and certain oncoproteins contain a conserved UA-rich sequence in the 3' untranslated region. This sequence, which is composed of several interspersed repeats of the octanucleotide UUAUUUAU, has been shown to destabilize mRNA in some eukaryotes. However, this effect is not seen when mRNAs are transferred to Xenopus oocytes, which made it possible to separate stability from translational regulation. For interferon, granulocyte-macrophage colony-stimulating factor, and c-fos RNAs, the UA-rich sequence was observed to preclude mRNA translation.
Developing an activity-based costing approach for system development and implementation (2003)

This paper proposes the use of the Activity Based Costing (ABC) approach to software estimation. Like other more traditional approaches to software estimation, ABC provides man-day estimates. In addition, it also provides detailed costing information that is useful for management control and decision making. The paper shows how the ABC approach can be applied to software estimation by building an ABC model using data from twenty-two projects in a financial services firm. The model is then used for estimation, and comparisons between estimated and actual man-day are computed (variance analysis). The data generated by the model and from the variance analysis are useful for management control and decision making in areas such as resource allocation, outsourcing of specific development activities, and learning from adoption of new development tools and practices.
Large area sensors for active acoustic control systems (1989)

The design and development of a composite piezoelectric polymer (PVDF) sensor for use in an active acoustic control system is presented. Large area PVDF plates are encapsulated in a polymer matrix to detect both the incident and reflected signals in an underwater pulse tube at low frequencies. These signals are amplified, phase shifted, and then used to drive an absorbing transducer to negate reflections. The results of this system are compared with earlier data [X.-Q. Bao et al., J. Acoust. Soc. Am. Suppl. 1 84, S49 (1988)] that utilized piezoceramic spherical hydrophones.
Competitive Sorption of Pyrene, Phenanthrene, and Naphthalene on Multiwalled Carbon Nanotubes (2006)

Knowledge of toxic chemical sorption by carbon nanotubes (CNTs) is critical for environmental application of CNTs as superior sorbents and for environmental risk assessment of both CNTs and toxic chemicals. Single-solute sorption results were reported in the literature, however, they cannot be used for predicting pollutant sorption by CNTs in wastewater and natural water systems where multiple organic contaminants are present. In this study, competitive sorption of pyrene, phenanthrene, and naphthalene on a multiwalled CNT material was investigated. All isotherms in single-, bi-, and tri-solute systems were fitted well by the Dubinin-Ashtakhov (DA) model. The isotherm of a given primary solute changed from being significantly nonlinear to nearly linear when competitors were added. The observed competitive sorption depended on the relative equilibrium concentrations of both primary and cosolutes. Significant competition was observed at relatively low concentrations of primary solute and high concentrations of competitors, while competition was much weaker in the case of relatively high concentrations of primary solute and low competitor concentrations. When the relative concentration of primary solute (Ce/Cs) approached 1, competition by other solutes seemed to disappear. Sorption and competition of three polycyclic aromatic hydrocarbons (PAHs) on CNTs could not be explained with either pore-filling or partition-adsorption mechanisms. A Polanyi-based surface adsorption mechanism was proposed to interpret the observed sorption and competition.