gebhart/patrepeval huggingface dataset:
A MACHINE LEARNING BASED APPROACH FOR DETECTING NON-DETERMINISTIC TESTS AND ITS ANALYSIS IN MOBILE APPLICATION TESTING (2018)

Hundreds of different mobile devices are on the market, produced by different vendors, and with different software features and hardware components. Mobile applications, while running on different devices, may behave differently due to variations in the hardware or O.S. components. Since mobile applications are expected to be deployed and executed on diverse mobile platforms, they must be validated on different mobile platforms and devices. Due to the peculiarities of mobile application development, there is a need for a quality assurance approach that focuses on its challenges. Moreover, mobile test executions take a long time because all the tests were executed in different environments and developers had to create complex tear down procedures. Such procedures were lengthy and far from perfect, leading to unpredictable failures. Regression testing is a crucial part of Mobile app development and it checks that software changes do not break existing functionality. An important assumption of regression testing is that test outcomes are deterministic and tests are expected to either always pass or always fail for the same code under test. But unfortunately, in real projects multiple release cycles, some tests— often called flaky tests—have non-deterministic outcomes. These tests undermine the regression testing cycle as they make it difficult to rely on test results. These results significantly reduced the trust in the tests and thus undermined the whole mobile app test automation effort. We trained machine learning classifiers separately on each test result dataset and compared performance across datasets. The proposed model predicts result types as Non-Deterministic or Deterministic tests from the regression suite results executed in various release cycles.
The Myopias: Basic Science and Clinical Management (1986)

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Über die Vilsmeier‐Formylierung von ungesättigten Kohlenwasserstoffen (1966)

Abstract Die Lokalisationsenergien L einer Anzahl konjugierter Polyene weisen auf ihre leichte Substituierbarkeit durch Vilsmeier‐Komplexe hin. Bei Kohlenwasserstoffen mit dem System des 2‐Vinyl‐butadiens‐(1.3) und 2‐Phenyl‐butadiens‐(1.3) gelingt Monoformylierung zu Imoniumsalzen. Isobutylen wird fünffach zu einem gelben Trikation substituiert, beim 2‐Phenyl‐propen konnten die Salze der Mono‐ und Triformylierung isoliert werden.
Penalized weighted least-squares as a metal streak artifacts removal technique in computed tomography (2002)

Assesses the applicability of single-energy (SE) and dual-energy (DE) penalized weighted-least squares (PWLS) methods in the removal of metal streak artifacts. For that purpose the authors conduct experiments with a phantom containing opaque regions. Their earlier studies on computer-generated sets of data showed that both SE PWLS and DE PWLS methods are superior to a standard FBP-based method. The authors are interested to what extent the good performance of both SE and DE PWLS methods is preserved when using experimental data. Of particular relevance is that neither scatter in the body nor the polychromaticity of the X-ray source were taken into account in the computer-generated sets of data.
'Being a foreigner, I may be punished if I make a small mistake': assessing transcultural experiences in caring for patients (1997)

Qualitative methods are useful for assessing the transcultural experiences of IMG residents and for informing curricular changes in residency training. These methods may help other training programmes to identify the particular needs of their trainees in addressing emotionally laden experiences.
Heparin-Binding EGF-Like Growth Factor Induces Heart Interstitial Fibrosis via an Akt/mTor/p70s6k Pathway (2012)

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is essential for maintaining normal function of the adult heart and is known to play an important role in myocardial remodeling. In the present study, we observed that heart-specific HB-EGF transgenic (TG) mice had systolic dysfunction with decreased fractional shortening (FS%), increased end-systolic diameter (LVIDs) at 5 months of age, increased heart fibrosis, and increased mRNA expression of Col1α1 and Col3α1 at 1, 3, 5 and 7 months of age compared to nontransgenic (NTG) littermates. However, the left ventricular anterior wall thickness at end-systole (LVAWs) of the TG mice was not different than the NTG mice. Phosphorylation levels of Akt, mTor and p70s6k were increased due to HB-EGF expression in TG mice compared with the NTG mice at 3 and 7 months of age. Additionally, activated Akt, mTor and p70s6k were co-localized with vimentin to cardiac fibroblasts isolated from TG mice. Furthermore, HB-EGF significantly increased phosphorylation levels of Akt, mTor and p70s6k and increased expression of type I collagen in cultured primary cardiac fibroblasts. Rapamycin (Rapa) and CRM197, inhibitors of mTor and HB-EGF respectively, could inhibit the expression of type I collagen in the cultured primary cardiac fibroblasts and Rapa suppressed interstitial fibrosis of the heart tissues in vivo. In addition, a BrdU assay showed that HB-EGF increased proliferation of cardiac fibroblasts by 30% compared with cells without HB-EGF treatment. HB-EGF-induced proliferation was completely diminished in the presence of Rapa. These results suggest that HB-EGF induced heart fibrosis and proliferation of cardiac fibroblasts occurs through activation of the Akt/mTor/p70s6k pathway.
Safety of Blocking Vascular Adhesion Protein‐1 in Patients with Contact Dermatitis (2005)

Vascular adhesion protein-1 mediates leukocyte binding to vascular endothelia and migration to tissues. It is upregulated in inflammatory conditions. We studied the safety of vascular adhesion protein-1 blockade by a single dose of the mouse monoclonal antibody vepalimomab in patients with nickel-induced allergic contact dermatitis lesions. Vepalimomab, 0.05-0.50 mg kg(-1) was safe and well tolerated. Four of nine patients reported adverse events of mild to moderate intensity. Human antimouse antibodies were detected after infusion in all the patients and they remained above the basal level for at least one month. Vepalimomab dose-dependently labelled vascular adhesion protein-1 in the inflamed skin. Luminal upregulation of vascular adhesion protein-1 on the endothelium upon inflammation was demonstrated for the first time in patients in vivo. Vepalimomab was found on the endothelium up to 24 hr after dosing whilst it was cleared from the circulation with an apparent half-life of 25-50 min. The results provide in vivo support for the concept of blocking vascular adhesion protein-1 in human disease states and support previous proposals that vascular adhesion protein-1 is a potential target molecule for inhibition of inflammatory reactions.
Homogeneous Seeding of Mesenchymal Stem Cells into Nonwoven Fabric for Tissue Engineering (2003)

Mesenchymal stem cells (MSCs) were isolated from the bone marrow of rats and seeded into a nonwoven fabric of polyethylene terephtalate (PET) by agitation and static methods. MSC attachment was investigated in terms of the number of cells attached to the fabric, their distribution inside the fabric, and cell damage. The number of MSCs attached was greater for the agitation seeding method than for the static seeding method. The higher the rotating speed in the agitation seeding method, the greater the number of cells attached. When the cell suspension was seeded into the fabric in culture medium volumes of 50 and 200 microL per well of the culture plate or per culture tube, the best cell attachment was observed for the tube culture group at the larger volume. These cells attached more homogeneously throughout the fabric in greater numbers than was the case for the other culture groups. It is possible that agitation of the cell suspension allows cells to infiltrate uniformly inside the fabric, resulting in a homogeneous distribution of the cells in the fabric. A biochemical study revealed that neither the agitation nor static seeding method damaged cells, irrespective of the medium volume and the type of culture vessel. We conclude that the agitation seeding method is a promising method by which to formulate a homogeneous construct of fabric and MSCs.
Electron-transfer reactions of benzene-1,2-diols with hexachloroiridate(IV) in acidic perchlorate media (1977)

The kinetics of oxidation of a series of benzene-1,2-diols by hexachloroiridate(IV) have been investigated by the stopped-flow technique in aqueous acidic perchlorate media. The reactions are first order in the concentrations of both reactants and independent of acidity and added [IrCl6]3–. The experimental results are discussed in the light of Marcus theorywith reference to previous findings on the kinetic behaviour of benzene-1,4-diols. The dependence of the free energies of activation on the free energies of reaction provides information on the mechanism of these non-complementary redox reactions.
New Methylene Blue as A Reticulocyte Stain* (1949)

New Methylene Blue as A Reticulocyte Stain* George Brecher, M.D. George Brecher, M.D. From the National Institutes of Health, Bethesda 14, Maryland Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 19, Issue 9_ts, September 1949, Pages 895–896, https://doi.org/10.1093/ajcp/19.9_ts.895 Published: 01 September 1949 Article history Received: 01 July 1949 Published: 01 September 1949
Monolithically integrated dye-doped PDMS long-pass filters for disposable on-chip fluorescence detection (2006)

We report the fabrication of high quality monolithically integrated optical long-pass filters, for use in disposable diagnostic microchips. The filters were prepared by incorporating dye molecules directly into the microfluidic chip substrate, thereby providing a fully integrated solution that removes the usual need for discrete optical filters. In brief, lysochrome dyes were added to a poly(dimethylsiloxane) (PDMS) monomer prior to moulding of the microchip from a structured SU-8 master. Optimum results were obtained using 1 mm layers of PDMS doped with 1200 microg mL(-1) Sudan II, which resulted in less than 0.01% transmittance below 500 nm (OD 4), >80% above 570 nm, and negligible autofluorescence. These spectral characteristics compare favourably with commercially available Schott-glass long-pass filters, indicating that high quality optical filters can be straightforwardly integrated into the form of PDMS microfluidic chips. The filters were found to be robust in use, showing only slight degradation after extended illumination and negligible dye leaching after prolonged exposure to aqueous solutions. The provision of low cost high quality integrated filters represents a key step towards the development of high-sensitivity disposable microfluidic devices for point-of-care diagnostics.
Correlation between symptoms developed after the oral ingestion of 50 g lactose and results of hydrogen breath testing for lactose intolerance (2008)

Evaluating symptoms developed after ingestion of 50 g lactose can be used as a simple screening test to select patients who need to be referred for lactose intolerance testing.
Polycyanurates find applications; their chemistry remains puzzling (1994)

RETURN TO ISSUEPREVNewsNEXTPolycyanurates find applications; their chemistry remains puzzlingSTEPHEN C. STINSONView Author Information C&EN Northeast News BureauCite this: Chem. Eng. News 1994, 72, 37, 30–32Publication Date (Print):September 12, 1994Publication History Published online11 November 2010Published inissue 12 September 1994https://pubs.acs.org/doi/10.1021/cen-v072n037.p030https://doi.org/10.1021/cen-v072n037.p030newsACS PublicationsCopyright © 1994 AMERICAN CHEMICAL SOCIETYArticle Views5Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Inorganic carbon compounds,Materials,Military science,Polymers Get e-Alerts
Intussusception among Infants Given an Oral Rotavirus Vaccine (2001)

The strong association between vaccination with RRV-TV and intussusception among otherwise healthy infants supports the existence of a causal relation. Rotavirus vaccines with an improved safety profile are urgently needed.
Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin‐labeled MRI (2001)

The influence of anesthetic agents on cerebral blood flow (CBF) was tested in normal rats. CBF is quantified with arterial spin-labeled MRI in rats anesthetized with either an opiate (fentanyl), a potent inhalation anesthetic agent (isoflurane), or a barbiturate (pentobarbital) using doses commonly employed in experimental paradigms. CBF values were found to be about 2.5-3 times lower in most regions analyzed during anesthesia with either fentanyl (with N(2)O/O(2)) or pentobarbital vs. isoflurane (with N(2)O/O(2)), in agreement with findings utilizing invasive measurement techniques. CBF was heterogeneous in rats anesthetized with isoflurane (with N(2)O/O(2)), but relatively homogeneous in rats anesthetized with either fentanyl (with N(2)O/O(2)) or pentobarbital, also in agreement with studies using other techniques. Magn Reson Med 46:202-206, 2001.
Review of Mid- to High-Temperature Sulfur Sorbents for Desulfurization of Biomass- and Coal-derived Syngas (2009)

This review examines state-of-the-art mid- and high-temperature sulfur sorbents that remove hydrogen sulfide (H2S) from syngas generated from coal gasification and may be applicable for use with biomass-derived syngas. Biomass feedstocks contain low percentages of protein-derived sulfur that is converted primarily to H2S, as well as small amounts of carbonyl sulfide (COS) and organosulfur compounds during pyrolysis and gasification. These sulfur species must be removed from the raw syngas before it is used for downstream fuel synthesis or power generation. Several types of sorbents based on zinc, copper, iron, calcium, manganese, and ceria have been developed over the last two decades that are capable of removing H2S from dry coal-derived syngas at mid- to high-temperature ranges. Further improvement is necessary to develop materials more suitable for desulfurization of biomass-derived syngas because of its hydrocarbon, tar, and potentially high steam content, which presents different challenges as compared to desulfurization of coal-derived syngas.
The route and significance of endogenous synthesis of alkaloids in animals (1982)

There is now substantial evidence that several TIQs and beta-carbolines are present in vivo and increase during certain pathological conditions. It still remains to be determined, however, precisely what roles they play in endogenous functions and whether or not they are critical for the expression of these pathological conditions. Accumulating biochemical information continues to support the notion that these compounds can act as false transmitters. The exciting new findings, which will certainly receive a great deal more attention, concern the interaction of some of the beta-carbolines with the benzodiazepine receptor. Determining if a beta-carboline is an endogenous receptor ligand will attract further research interest on the theoretical and specifically clinically-directed levels. Biochemical, morphological, and behavioral data indicate that some of the condensation products can act as neurotoxins. Very few experiments have included an examination of long-term effects of exposure to one of these alkaloids, so the amount of information on this issue is limited. Chronic rather than acute administration of an alkaloid is more likely to mimic the pathological states in which these compounds are hypothesized to play a role. Biochemically, both the dopaminergic and serotonergic systems have been shown to be affected by chronic treatments with certain alkaloids. Progressive and long-term behavioral alterations also have been reported. Such changes may reflect an adaptation to an increase or decrease in activity of particular systems or a neurotoxic action.
Isolation of Labradorins 1 and 2 from <i>Pseudomonas syringae</i> pv. <i>coronafaciens</i> (2002)

Investigation of Pseudomonas syringae pv. coronafaciens cancer cell growth inhibitory constituents led to the isolation of 2-isobutyl-5-(3-indolyl)oxazole (1) and 2-n-pentyl-5-(3-indolyl)oxazole (2f), designated labradorins 1 (1) and 2 (2f), related to pimprinine (2a). The structures were deduced by spectroscopic techniques and X-ray crystal structure determinations. Labradorin 1 (1) afforded GI(50) microg/mL values of 9.8 and 6.2 against the human cancer cell lines NCI-H 460 (lung-NSC) and BXPC-3 (pancreas-a).
An Experimental Implementation of Migration Algorithms On the Intel Hypercube (1987)

This study was aimed at testing whether the Intel Hypercube is suitable for geo physical data processing—i.e., whether the multiprocessing capability of the Hy percube can achieve high performance at low cost in carrying out large-scale geo physical data processing tasks. Two basic migration algorithms—phase shift plus in terpolation migration, and second order in time, fourth order in space, finite differ ence migration—were implemented on the Hypercube. The multiprocessing algo rithm designs were based on the fol lowing issues: control, partitioning, synchronization, scheduling, communica tion, and optimization. The concurrent pro cessing in the d6 Hypercube speeds up the execution by three to four fold over a VAX 11-780. However, the limitations on the size of array by the available memory in the cube manager and the nodes, and the overhead incurred for communication and synchronization, make the present Hypercube system unsuitable for realistic geophysical data processing.
Space Resolved, in Operando X-ray Absorption Spectroscopy: Investigations on Both the Anode and Cathode in a Direct Methanol Fuel Cell (2012)

In operando space resolved XAS measurements on a catalysts coated membrane anode and cathode during methanol oxidation were performed through three different XAS windows at each electrode. Preheated methanol was pumped to the anode (PtRu/VC), and two different levels of nonhumidified O2 (providing O2 excess or O2 starvation) were pumped to the cathode (Pt/VC). At the anode, the methanol flowed upward; i.e., it entered the cell from near the bottom window and CO2 and other products exited near the top. At the cathode, oxygen was in counter flow, i.e., downward with inlet near the top. The relative OH and CO coverages on both the anode and cathode were followed using the Δμ-XANES technique at each window during operation at several current levels. A strong spatial correlation between the OH adsorbate coverage on the cathode and that on the anode located just across the proton exchange membrane (PEM) is found, this arising from the H+ “cross-talk” between the anode and cathode through the PEM. To our knowledge, these are the first results to show such direct correlation in space and potential between OH adsorbates on the cathode with H+ production at the anode, and it points directly to the importance of the H+ concentration in the kinetics of the oxygen reduction reaction. Finally, the electrode with the slowest reaction rate (methanol oxidation at the anode at high O2 flow or oxygen reduction at the cathode at low O2 flow) dictates the local potential and therefore in part the local adsorbate coverage on the opposite electrode.
Hints on Test Data Selection: Help for the Practicing Programmer (1978)

In many cases tests of a program that uncover simple errors are also effective in uncovering much more complex errors. This so-called coupling effect can be used to save work during the testing process.
Effects of mechanical loading on the tissues of the rabbit knee (1984)

We studied changes in subchondral bone and articular cartilage in an animal model of osteoarthrosis. In this model we applied repetitive impulsive loads to rabbits' knees. Their legs were held in short leg splints so the rabbits were unable to dampen the peak applied load with ankle flexion. After sacrifice, at 1 day to 6 weeks, we studied proximal tibial load-bearing cartilage histologically, biochemically, and with radioactive sulfate uptake. We also studied the subchondral bone under that cartilage histologically, histomorphometrically, with bone scan (99mTc pyrophosphate), and by tetracycline labeling. An increase in 99mTc labeling of the subchondral bone was the first reliable change observed. This was followed by an increase in tetracycline labeling, bone formation, and a decrease in porosity, which has been associated with relative stiffening of bone. Horizontal splitting and deep fibrillation of the overlying articular cartilage followed the early bone changes. All of these changes preceded changes in content and characterization of cartilage proteoglycans or increased chondrocyte activity as manifested by incorporation of radioactive sulfate. In this model the early bone changes preceded changes in the articular cartilage. The deep splitting of articular cartilage occurred prior to metabolic alteration of that tissue.
Targeted cytotoxic analogue of bombesin/ gastrin-releasing peptide inhibits the growth of H-69 human small-cell lung carcinoma in nude mice (1999)

Recently, we developed a powerful cytotoxic analogue of bombesin AN-215, in which the bombesin-like carrier peptide Gln-Trp-Ala-Val-Gly-His-Leu-psi(CH2-NH)-Leu-NH2 (RC-3094) is conjugated to a potent derivative of doxorubicin, 2-pyrrolinodoxorubicin (AN-201). Small-cell lung carcinomas (SCLCs) are known to express high levels of bombesin receptors. We evaluated whether these receptors could be used for targeting cytotoxic bombesin analogue to H-69 SCLC cells. H-69 cells were xenografted into male nude mice, which then received an intravenous injection of AN-215, cytotoxic radical AN-201, the carrier peptide RC-3094 alone or unconjugated mixture of RC-3094 and AN-201. The levels of mRNA for bombesin receptor subtypes were evaluated by reverse transcription-polymerase chain reaction. In vitro, both the analogue AN-215 and the radical AN-201 showed strong antiproliferative effects on H-69 cells, AN-215 requiring more time to exert its action at 10(-8) M concentration than AN-201. In vivo, the growth of H-69 SCLC tumours was significantly inhibited by the treatment with 200 nmol kg(-1) of AN-215, while equimolar doses of the cytotoxic radical AN-201 or the mixture of AN-201 and the carrier peptide were toxic and produced only a minor tumour inhibition as compared with control groups. mRNA for bombesin receptor subtypes 2 (BRS-2) and 3 (BRS-3) was detected in H-69 tumours. The mRNA levels for BRS-3, but not for BRS-2, were lower in the AN-215-treated tumours as compared with controls. Our results demonstrate that the cytotoxic bombesin analogue AN-215 could be considered for targeted therapy of tumours, such as SCLC, that express bombesin receptors.