gebhart/patrepeval huggingface dataset:
Learning shape correspondence with anisotropic convolutional neural networks (2016)

Establishing correspondence between shapes is a fundamental problem in geometry processing, arising in a wide variety of applications. The problem is especially difficult in the setting of non-isometric deformations, as well as in the presence of topological noise and missing parts, mainly due to the limited capability to model such deformations axiomatically. Several recent works showed that invariance to complex shape transformations can be learned from examples. In this paper, we introduce an intrinsic convolutional neural network architecture based on anisotropic diffusion kernels, which we term Anisotropic Convolutional Neural Network (ACNN). In our construction, we generalize convolutions to non-Euclidean domains by constructing a set of oriented anisotropic diffusion kernels, creating in this way a local intrinsic polar representation of the data (`patch'), which is then correlated with a filter. Several cascades of such filters, linear, and non-linear operators are stacked to form a deep neural network whose parameters are learned by minimizing a task-specific cost. We use ACNNs to effectively learn intrinsic dense correspondences between deformable shapes in very challenging settings, achieving state-of-the-art results on some of the most difficult recent correspondence benchmarks.
Compactness of Geographic Shape: Comparison and Evaluation of Measures (1985)

Geographic shape compactness is of concern in such contexts as urban morphology, political districting, and accuracy of enumeration unit values. The purpose of the present paper is to compare, categorize, and evaluate the various methods suggested for measuring compactness. Review of suggested compactness indices resulted in the identification of four categories, based upon: 1) perimeter-area measurement, 2) single parameters of related circles, 3) direct comparison to a standard shape, and 4) dispersion of elements of a shape's area. In all, eleven indices were calculated for a sample of U.S. counties and their frequency distributions were compared. Additionally, similarities and differences in the units of high, median, and low compactness were identified. Within each category, indices exhibited considerable similarity while significant differences were evident from category to category. These differences suggested variation in accuracy with which the indices measure compactness. It was hypothesized that measures based upon dispersion of elements of a shape's area would provide the most accurate measure because they consider the shape as a whole while the other indices do not. Determination of the accuracy with which each index measures compactness supported this hypothesis. Indices based upon direct comparison to a standard shape were found to be of similar accuracy and, therefore, also judged to be suitable compactness measures. Those measures based upon perimeter-area measurement and single parameters of related circles were determined to be considerably less accurate measures of compactness.
Methylnaltrexone, a peripherally acting opioid receptor antagonist, enhances tumoricidal effects of 5-Fu on human carcinoma cells. (2009)

At its therapeutic concentrations for opioid-induced constipation, methylnaltrexone does not attenuate and in fact may enhance the tumoricidal activity of 5-FU. Enhanced 5-FU activity may be attributed to the distinct pathways of 5-FU and methylnaltrexone, an effect that could give methylnaltrexone a complementary role in the treatment of cancer with chemotherapeutic agents.
New dimension of medicinal plants as animal feed (2006)

The medicinal plants and herbs have been used for many years in the treatment of various diseases in animals and human beings. Now-a-days, utilization of these medicinal plants is increasing. These are used in animal feed as the growth promoters. Due to prohibition of most of the antimicrobial growth promoters in animal feed because of their residual effects, plant extracts are becoming more popular. They act as antibacterial, antioxidant, anticarcinogenic, antifungal, analgesic, insecticidal, anticoccidial and growth promoters. These plant extracts compete with the synthetic drugs. Majority of medicinal plants do not have the residual effects. Azadiracht indica, Zizyphus vulgaris, Ocimum gratissimum and Atlanta monophylla have the strong antibacterial activity, whereas ocimum plant has strong antioxidant, anticarcinogenic, antifungal, analgesic and antipyretic properties. Leaves of Azadirachta indica are used for feeding and reducing the parasitic load of animals. The fruit of Azadirachta indica also has the anticoccidial activity for poultry.
Local Over-Expression of VEGF-DΔNΔC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis (2014)

Local over-expression of VEGF-DΔNΔC in the UtAs of pregnant mid-gestation sheep reduced vasoconstriction, promoted endothelial cell proliferation and showed a trend towards increased UABF. Studies in cultured UAECs indicate that VEGF-DΔNΔC may act in part through upregulation of eNOS and iNOS.
Recent technology and usage of plastic lenses in image taking objectives (2005)

Recently, plastic lenses produced by injection molding are widely used in image taking objectives for digital cameras, camcorders, and mobile phone cameras, because of their suitability for volume production and ease of obtaining an advantage of aspherical surfaces. For digital camera and camcorder objectives, it is desirable that there is no image point variation with the temperature change in spite of employing several plastic lenses. At the same time, due to the shrinking pixel size of solid-state image sensor, there is now a requirement to assemble lenses with high accuracy. In order to satisfy these requirements, we have developed 16 times compact zoom objective for camcorder and 3 times class folded zoom objectives for digital camera, incorporating cemented plastic doublet consisting of a positive lens and a negative lens. Over the last few years, production volumes of camera-equipped mobile phones have increased substantially. Therefore, for mobile phone cameras, the consideration of productivity is more important than ever. For this application, we have developed a 1.3-mega pixels compact camera module with macro function utilizing the advantage of a plastic lens that can be given mechanically functional shape to outer flange part. Its objective consists of three plastic lenses and all critical dimensions related to optical performance can be determined by high precise optical elements. Therefore this camera module is manufactured without optical adjustment in automatic assembling line, and achieves both high productivity and high performance. Reported here are the constructions and the technical topics of image taking objectives described above.
Dynamic Conditional Correlation (2002)

Time varying correlations are often estimated with multivariate generalized autoregressive conditional heteroskedasticity (GARCH) models that are linear in squares and cross products of the data. A new class of multivariate models called dynamic conditional correlation models is proposed. These have the flexibility of univariate GARCH models coupled with parsimonious parametric models for the correlations. They are not linear but can often be estimated very simply with univariate or two-step methods based on the likelihood function. It is shown that they perform well in a variety of situations and provide sensible empirical results.
The azetidines. Recent synthetic developments (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleThe azetidines. Recent synthetic developmentsNorman H. Cromwell and Barry. PhillipsCite this: Chem. Rev. 1979, 79, 4, 331–358Publication Date (Print):August 1, 1979Publication History Published online1 May 2002Published inissue 1 August 1979https://pubs.acs.org/doi/10.1021/cr60320a003https://doi.org/10.1021/cr60320a003research-articleACS PublicationsRequest reuse permissionsArticle Views1504Altmetric-Citations142LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP (2008)

Glucocorticoids (GCs) are known to inhibit mitogen-activated protein kinase (MAPK) signaling. This has been suggested to involve induced expression of MAPK-phosphatase 1 (DUSP1), which dephosphorylates and inactivates MAPKs. However, the mechanism for the transcriptional activation by GCs of DUSP1 or the identification of a GC-responsive region of the gene has so far not been described. To identify GC receptor (GR) binding to the human DUSP1 promoter in vivo, we used a chromatin immunoprecipitation (ChIP) assay and found GR to bind to a region approximately -1.4 kb upstream of the transcription start site. Using promoter deletion constructs, we identified a GC-responsive region between position -1266 and -1380 bp of the DUSP1 promoter. However, no direct binding of GR to this GC-responsive region was detected in an electrophoretic mobility shift assay (EMSA). Instead, we identified binding of CCAAT/enhancer-binding protein beta (C/EBPbeta) to a region between -1311 and -1304 bp of the DUSP1 promoter by EMSA and ChIP. Furthermore, mutation of the C/EBP binding site resulted in a dramatic loss of GC-inducible reporter gene expression, demonstrating the GC responsiveness of the DUSP1 gene to be located to a binding site for C/EBP in the DUSP1 promoter. Also, given that a GR mutant (GR(LS7)), incapable of transactivating through GC-responsive elements, still was able to bind to the DUSP1 gene in vivo and induce DUSP1 mRNA expression following treatment with GCs suggests the mode of GC activation to be mediated by a tethering mechanism involving the GR and the DUSP1 promoter-bound C/EBPbeta.
Sinoatrial Node Pacemaker Activity Requires Ca<sup>2+</sup>/Calmodulin-Dependent Protein Kinase II Activation (2000)

Cardiac beating arises from the spontaneous rhythmic excitation of sinoatrial (SA) node cells. Here we report that SA node pacemaker activity is critically dependent on Ca(2+)/calmodulin-dependent protein kinase II (CaMKII). In freshly dissociated rabbit single SA node cells, inhibition of CaMKII by a specific peptide inhibitor, autocamtide-2 inhibitory peptide (AIP, 10 micromol/L), or by KN-93 (0.1 to 3.0 micromol/L), but not its inactive analog, KN-92, depressed the rate and amplitude of spontaneous action potentials (APs) in a dose-dependent manner. Strikingly, 10 micromol/L AIP and 3 micromol/L KN-93 completely arrested SA node cells, which indicates that basal CaMKII activation is obligatory to the genesis of pacemaker AP. To understand the ionic mechanisms of the CaMKII effects, we measured L-type Ca(2+) current (I(Ca, L)), which contributes both to AP upstroke and to pacemaker depolarization. KN-93 (1 micromol/L), but not its inactive analog, KN-92, decreased I:(Ca, L) amplitude from 12+/-2 to 6+/-1 pA/pF without altering the shape of the current-voltage relationship. Both AIP and KN-93 shifted the midpoint of the steady-state inactivation curve leftward and markedly slowed the recovery of I(Ca, L) from inactivation. Similar results were observed using the fast Ca(2+) chelator BAPTA, whereas the slow Ca(2+) chelator EGTA had no significant effect, which suggests that CaMKII activity is preferentially regulated by local Ca(2+) transients. Indeed, confocal immunocytochemical imaging showed that active CaMKII is highly localized beneath the surface membrane in the vicinity of L-type channels and that AIP and KN-93 significantly reduced CaMKII activity. Thus, we conclude that CaMKII plays a vital role in regulating cardiac pacemaker activity mainly via modulating I(Ca, L) inactivation and reactivation, and local Ca(2+) is critically involved in these processes.
New approach of the navigation control of small size UAVs (2010)

In unmanned aerial vehicle operations as well as in aviation the airflow direction and speed plays a major role. The wind speed may limit the use of aircraft, and determines the direction of the takeoff and landing. In the case of small size UAVs (0.5 - 4 m wingspan, 0.5 - 10 kg takeoff weight) the strength and the direction of the wind is quite important, because the airspeed of the vehicle is in the same scale, and the turbulence can affect the flight path. The general methods of wind measurement cannot be applied onboard of the UAV. Although the ground measured wind data is sufficient for the takeoff, but it is irrelevant when the UAV is landing in a different place, e.g. on a far field. In that case, the wind speed and direction must be measured onboard the vehicle, before the landing maneuver. The aim of the research is the real time determination of the dominant wind data with the onboard sensors.
Stress and addiction: contribution of the corticotropin releasing factor (CRF) system in neuroplasticity (2012)

Corticotropin releasing factor (CRF) has been shown to induce various behavioral changes related to adaptation to stress. Dysregulation of the CRF system at any point can lead to a variety of psychiatric disorders, including substance use disorders (SUDs). CRF has been associated with stress-induced drug reinforcement. Extensive literature has identified CRF to play an important role in the molecular mechanisms that lead to an increase in susceptibility that precipitates relapse to SUDs. The CRF system has a heterogeneous role in SUDs. It enhances the acute effects of drugs of abuse and is also responsible for the potentiation of drug-induced neuroplasticity evoked during the withdrawal period. We present in this review the brain regions and circuitries where CRF is expressed and may participate in stress-induced drug abuse. Finally, we attempt to evaluate the role of modulating the CRF system as a possible therapeutic strategy for treating the dysregulation of emotional behaviors that result from the acute positive reinforcement of substances of abuse as well as the negative reinforcement produced by withdrawal.
Role of Social Insurance in Providing Fringe Benefits (1965)

The economic security of individuals and their families against the hazards arising from such risks as old-age retirement, sickness (both short-term and long-term), unemployment, and death can be provided through several different methods. The most fundamental method, of course, is through the action of the individual himself (or, what amounts to virtually the same thing, through the efforts of the family group with which he is associated). Another method is through measures developed for what might be termed private groups-whether these be associations of individuals or arrangements developed in the course of employment (by the employer unilaterally or by collective-bargaining processes). The remaining method is through governmental action; from certain viewpoints, this might be said to be merely a broader development of the other two methods. Economic security can be provided through governmental means in a number of ways. Perhaps the most rudimentary procedure is when the government requires employers to provide the benefit protection. In most instances, this is not too satisfactory because of enforcement and administrative problems. Another
A CONVENIENT METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE-CATIONIC PEPTIDE CONJUGATES (2005)

A method was developed for the synthesis of oligonucleotide-cationic peptide conjugates in solution phase by disulfide bond formation. Precipitation was avoided by the easily removable triethylammonium trifluoroacetate (TEATFAc) salt which served at the same time as a buffer of the reaction mixture. The fast and high yielding disulfide bond formation was due to the Npys thio protecting and activating group of Cys. A solution of the free 5-thiol modified oligonucleotide obtained from Poly-Pak purification was used for conjugation.
Automatic set instance extraction using the web (2009)

An important and well-studied problem is the production of semantic lexicons from a large corpus. In this paper, we present a system named ASIA (Automatic Set Instance Acquirer), which takes in the name of a semantic class as input (e.g., "car makers") and automatically outputs its instances (e.g., "ford", "nissan", "toyota"). ASIA is based on recent advances in web-based set expansion - the problem of finding all instances of a set given a small number of "seed" instances. This approach effectively exploits web resources and can be easily adapted to different languages. In brief, we use language-dependent hyponym patterns to find a noisy set of initial seeds, and then use a state-of-the-art language-independent set expansion system to expand these seeds. The proposed approach matches or outperforms prior systems on several English-language benchmarks. It also shows excellent performance on three dozen additional benchmark problems from English, Chinese and Japanese, thus demonstrating language-independence.
<i>In vivo</i> application of mAb directed against the γδ TCR does not deplete but generates “invisible” γδ T cells (2009)

mAb targeting the gammadelta TCR have been used for gammadelta T-cell depletion with varying success. Although the depletion-capacity of the anti-gammadelta TCR mAb clone GL3 has been disputed repeatedly, many groups continue to use gammadelta T-cell depletion protocols involving the mAb clone UC7-13D5 and find significant biological effects. We show here that treatment with both GL3 and UC7-13D5 antibodies does not deplete gammadelta T cells in vivo, but rather leads to TCR internalization and thereby generates "invisible" gammadelta T cells. We addressed this issue using anti-gammadelta TCR mAb injections into WT mice as well as into reporter TCR delta locus-histone 2B enhanced GFP knock-in mice, in which gammadelta T cells can be detected based on an intrinsic green fluorescence. Importantly, the use of TCR delta locus-histone 2B enhanced GFP mice provided here for the first time direct evidence that the "depleted" gammadelta T cells were actually still present. Our results show further that GL3 and UC7-13D5 mAb are in part cross-competing for the same epitope. Assessed by activation markers, we observed in vitro and in vivo activation of gammadelta T cells through mAb. We conclude that gammadelta T-cell depletion experiments must be evaluated with caution and discuss the implications for future studies on the physiological functions of gammadelta T cells.
Dynamic rolling locomotion by spherical mobile robots considering its generalized momentum (2010)

In this paper, we propose a spherical mobile robot, which is composed of a sphere-shaped outer shell and and a 2-d.o.f. mass-control device inside it. We assume that there exists rolling contact constraint between the spherical surface of the robot and the floor. Our purpose is to realize locomotion control of the robot by appropriately actuating the internal driving mechanism. First, we derive a mathematical model of the robot as a nonlinear differential-algebraic equation (DAE). There are two differences between the conventional rolling sphere problem and our robot: (1)our robot is allowed to spin around the vertical axis, and therefore (2)we have to consider not only kinematics but also dynamics of the robot, because the angular momentum around the vertical axis plays an essential role its behavior.
Fully Integrated Linear Single Photon Avalanche Diode (SPAD) Array with Parallel Readout Circuit in a Standard 180 nm CMOS Process (2011)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation S. Isaak, S. Bull, M. C. Pitter, Ian. Harrison; Fully Integrated Linear Single Photon Avalanche Diode (SPAD) Array with Parallel Readout Circuit in a Standard 180 nm CMOS Process. AIP Conf. Proc. 25 May 2011; 1341 (1): 175–180. https://doi.org/10.1063/1.3586979 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Reinforcement learning in multi-agent environment and ant colony for packet scheduling in routers (2007)

The packet scheduling in router plays an important role in the sense to achieve QoS differentiation and to optimize the queuing delay, in particular when this optimization is accomplished on all routers of a path between source and destination. In a dynamically changing environment a good scheduling discipline should be also adaptive to the new traffic conditions. To solve this problem we use a multi-agent system in which each agent tries to optimize its own behaviour and communicate with other agents to make global coordination possible. This communication is done by mobile agents. In this paper, we adopt the framework of Markov decision processes applied to multi-agent system and present a pheromone-Q learning approach which combines the standard Q-learning technique with a synthetic pheromone that acts as a communication medium speeding up the learning process of cooperating agents.
Synthese und Prüfung auf Herz‐Kreislauf‐Wirkung von N‐(3′‐Methoxybenzamidomethyl)‐D‐norephedrin und analogen Verbindungen (1976)

Abstract Es wird über die Synthese von N‐(3′‐Methoxybenzamidomethyl)‐D‐norephedrin ( 7 ) und analogen Verbindungen ( 1 – 6 , 8 – 29 ) aus N‐Chlormethyl‐carbonamiden und Aminen und ihre Prüfung am Langendorff ‐Herzen des Meerschweinchens berichtet. Einige Vertreter ( 3, 4, 7, 9, 13, 15 ) führen zu einer Erhöhung von Coronardurchfluß und Kontraktionsamplitude. Die N‐Amidomethyl‐β‐phenolalkanolamine 24 – 26, 27 und 29 , deren Synthese im Hinblick auf eine mögliche langanhaltende pressorische Wirkung erfolgte (chemische Retardpräparate), zeigen keine blutdrucksteigernden Effekte.
A modular scan-based testability system (2003)

The authors present a scan-based testability system that is an integral part of the cell-based design system at Microelectronics Center of North Carolina. The basic system consists of five modules: a scan-based audit to verify compliance with scan-based rules, a testability assessment module that projects fault coverage before any patterns are applied, a fast fault simulator that grades random and user-supplied patterns, an algorithmic test-pattern generator that produces test for faults that resist detection with random patterns or declares them redundant, and a test-pattern compactor to further reduce the size of the test-pattern set. The system serves as a platform for research into hierarchical methods, redundancy identification and removal, automated test point insertion, improved random test pattern generation, fault simulation, and boundary scan.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>