gebhart/patrepeval huggingface dataset:
A Novel Event-Based Incipient Slip Detection Using Dynamic Active-Pixel Vision Sensor (DAVIS) (2018)

In this paper, a novel approach to detect incipient slip based on the contact area between a transparent silicone medium and different objects using a neuromorphic event-based vision sensor (DAVIS) is proposed. Event-based algorithms are developed to detect incipient slip, slip, stress distribution and object vibration. Thirty-seven experiments were performed on five objects with different sizes, shapes, materials and weights to compare precision and response time of the proposed approach. The proposed approach is validated by using a high speed constitutional camera (1000 FPS). The results indicate that the sensor can detect incipient slippage with an average of 44.1 ms latency in unstructured environment for various objects. It is worth mentioning that the experiments were conducted in an uncontrolled experimental environment, therefore adding high noise levels that affected results significantly. However, eleven of the experiments had a detection latency below 10 ms which shows the capability of this method. The results are very promising and show a high potential of the sensor being used for manipulation applications especially in dynamic environments.
Ray tracing for indoor radio channel estimation (2002)

This paper describes the foundation for and implementation of a simple computer tool to evaluate the power/delay/carrier phase shift parameters of an indoor radio channel impulse response. The tool is based on a geometrical ray approximation of electromagnetic wavefronts. A graphic ray tracing technique is adapted to find all propagation paths within a three-dimensional scene between a user specified transmitter and receiver position. Each propagation path is characterized by a power/delay/phase vector. The set of all those vectors gives the site specific channel impulse response. Typical applications are for placement of base stations in Personal Communication Networks.
Nanoscale combined reactions: non-equilibrium α-Co formation in nanocrystalline ϶-Co by abnormal grain growth (2006)

II-2.
Perspective and Promise: a Century of Insect Acoustic Detection and Monitoring (2011)

Acoustic devices provide nondestructive, remote, automated detection, and monitoring of hidden insect infestations for pest managers, regulators, and researchers. In recent decades, acoustic devices of various kinds have been marketed for field use, and instrumented sample containers in sound-insulated chambers have been developed for commodity inspection. The efficacy of acoustic devices in detecting cryptic insects, estimating population density, and mapping distributions depends on many factors, including the sensor type and frequency range, the substrate structure, the interface between sensor and substrate, the assessment duration, the size and behavior of the insect, and the distance between the insects and the sensors. Considerable success has been achieved in detecting grain and wood insect pests. Microphones are useful sensors for airborne signals, but vibration sensors interface better with signals produced in solid substrates, such as soil, grain, or fibrous plant structures. Ultrasonic sensors are particularly effective for detecting wood-boring pests because background noise is negligible at > 20 kHz frequencies, and ultrasonic signals attenuate much less rapidly in wood than in air; grain, or soil. Problems in distinguishing sounds produced by target species from other sounds have hindered usage of acoustic devices, but new devices and signal processing methods have greatly increased the reliability of detection. One new method considers spectral and temporal pattern features that prominently appear in insect sounds but not in background noise, and vice versa. As reliability and ease of use increase and costs decrease, acoustic devices have considerable future promise as cryptic insect detection and monitoring tools.
Wave Field Synthesis: From Research To Applications (2004)

Publication in the conference proceedings of EUSIPCO, Viena, Austria, 2004
CVD of Compound Semiconductors: Precursor Synthesis, Development and Applications (1997)

Basic electronics introduction to vapour-phase epitaxy MOCVD ALE CBE precursor chemistry general classes synthesis purification effects of trace impurities on layer properties deposition of III-V semiconductors MOCVD ALE CBE deposition of II-VI semiconductors MOCVD future prospects.
Decidual Prolactin Silences the Expression of Genes Detrimental to Pregnancy (2007)

Although the main role of prolactin (PRL) in pregnant rodents is to sustain progesterone production by the corpus luteum, progesterone treatment of PRL or PRL receptor (PRL-R) null mice is unable to prevent fetal loss. We have previously shown that the rat decidua is a site of PRL production and action. In this report, we examined the hypothesis, using PRL null mice and rat decidual cell culture, that the absence of this hormone leads to the expression in the decidua of genes detrimental to pregnancy. The results show that decidual growth is normal in PRL null mice treated with PRL, progesterone, or their combination. However, the decidua of mice treated with progesterone starts expressing IL-6 and 20alpha-hydroxysteroid dehydrogenase (20alpha-HSD), two proteins absent from the decidua of wild-type mice and involved, respectively, in inflammation and progesterone catabolism. The expression of both IL-6 and 20alpha-HSD is prevented by PRL treatment. Our results further suggest that PRL inhibition of 20alpha-HSD expression is at the level of transcription and that decidual PRL (dPRL) inhibits 20alpha-HSD promoter activity. Inhibitors of Janus kinase 2 (Jak2) but not other kinases prevent dPRL down-regulation of the 20alpha-HSD promoter. Furthermore, cotransfection of the 20alpha-HSD promoter with expression vectors of constitutively active PRL-R, Jak2, or signal transducer and activator of transcription 5b (Stat5b) leads to substantial inhibition of promoter activity. Taken together, our investigation provides an explanation for the inability of progesterone to sustain pregnancy in PRL null mice and suggests that dPRL plays an important role in pregnancy by repressing the expression of IL-6 and 20alpha-HSD in the decidua. The study also demonstrates that PRL signals through the Jak2/Stat5 pathway to down-regulate 20alpha-HSD expression in the decidua.
Liposomal amphotericin B as a treatment for human leishmaniasis (2012)

LAMB proved to be highly efficacious and safe in over 8000 VL patients treated by MÉdecins Sans Frontières in South Asia, and its use was feasible even at primary healthcare level. Despite requiring higher doses, LAMB is the drug of choice to treat vulnerable groups (e.g., pregnant or HIV positive) and relapsing VL patients in East Africa. LAMB should be included in national VL guidelines and registered in all VL endemic countries. Its cost should be further reduced and regulatory pathways to prove bioequivalence for generic LAMB products should be implemented.
Alteration of Glutathione Level in Human Melanoma Cells: Effect of N‐Acetyl‐L‐Cysteine and its Analogues (1990)

The effects of N-acetyl-L-cysteine (L-NAC), N,N-diacetyl-L-cystine (oxidized form of L-NAC) and N-acetyl-D-cysteine on the intracellular glutathione (GSH) level and their toxicity were investigated in the human melanoma cell culture IGR1. L-NAC applied in 3 mM concentration for 24 hr decreased; when applied for 48 hr it did not alter the intracellular GSH level. Treatment with 1 mM L-NAC for 24 hr had no effect on cellular glutathione, whereas the same concentration applied for 48 hr resulted in an increase in the level of GSH. Both concentrations also induced cell injury as determined by protein assay and trypan blue staining. N,N-diacetyl-L-cystine (0.5 and 1.5 mM, 24 hr) induced a decrease in cellular glutathione content without any apparent cell toxicity. D-NAC (1 and 3 mM, 24 hr) did not influence the GSH level of the melanoma cells; however, it had toxic effects resulting in cell loss.
Purely functional system configuration management (2007)

System configuration management is difficult because systems evolve in an undisciplined way: packages are upgraded, configuration files are edited, and so on. The management of existing operating systems is strongly im-perative in nature, since software packages and config-uration data (e.g., /bin and /etc in Unix) can be seen as imperative data structures: they are updated in-place by system administration actions. In this paper we present an alternative approach to system configuration manage-ment: a purely functionalmethod, analogous to languages like Haskell. In this approach, the static parts of a config-uration — software packages, configuration files, control scripts — are built from pure functions, i.e., the results de-pend solely on the specified inputs of the function and are immutable. As a result, realising a system configuration becomes deterministic and reproducible. Upgrading to a new configuration is mostly atomic and doesn’t overwrite anything of the old configuration, thus enabling rollbacks. We have implemented the purely functional model in a small but realistic Linux-based operating system distribu-tion called NixOS. 1
Free radical scavenging reactions and antioxidant activities of silybin: Mechanistic aspects and pulse radiolytic studies (2009)

Silybin (extracted from Silybum marianum) is the major active constituent of silymarin which possesses a wide range of medicinal properties. These properties may be, in part, due to the potent scavenging capacity of oxidizing free radicals. In this context, scavenging radicals (hydroxyl, azide, dibromide anion radicals, nitrite, carbonate, etc.) of silybin have been studied to understand the mechanistic aspects of its action against free radicals. The transients produced in these reactions have been assigned and the rate constants have been measured by pulse radiolysis techniques. Reduction potential determined both by cyclic voltammetry gave a value 0.62+/-0.02 V vs NHE at pH 9. Quantum chemical calculations have been performed to further confirm the different activities of individual hydroxyl groups with the difference of heat of formation. Moreover, silybin also protected plasmid pUC18 DNA from soft X-ray radiation which induced strand breaks. These results are expected to be helpful for a better understanding of the anti-oxidative properties of silybin.
Ionic Hall effect in crystals: Independent versus cooperative hopping in AgBr and α-AgI (1990)

Consideration of the dynamics of the hopping process for independent point defects in an ionic crystal suggests that the ionic current cannot exhibit any Hall effect, to first order. An extensive series of measurements on silver bromide, which conducts predominantly by means of isolated, highly mobile silver interstitial ions, yielded no observable Hall signals. These measurements limit the ratio of the Hall mobility to the drift mobility of the interstitial ion in AgBr to less than 5% (at high temperatures) and to 10% (at lower temperatures). For the superionic \ensuremath{\alpha}-AgI, however, we find a Hall mobility which is approximately equal to the drift mobility, confirming earlier results of others. We argue that this Hall signal is a result of the strong correlations between the hopping ions, thus reflecting a fundamental qualitative difference between ``normal'' and superionic conductors.
Delegating network security with more information (2009)

Network security is gravitating towards more centralized control. Strong centralization places a heavy burden on the administrator who has to manage complex security policies and be able to adapt to users' requests. To be able to cope, the administrator needs to delegate some control back to end-hosts and users, a capability that is missing in today's networks. Delegation makes administrators less of a bottleneck when policy needs to be modified and allows network administration to follow organizational lines. To enable delegation, we propose ident++ - a simple protocol to request additional information from end-hosts and networks on the path of a flow. ident++ allows users and end-hosts to participate in network security enforcement by providing information that the administrator might not have or rules to be enforced on their behalf. In this paper we describe ident++ and how it provides delegation and enables flexible and powerful policies.
Sequential fractionation and isolation of subcellular proteins from tissue or cultured cells (2015)

Many types of studies require the localization of a protein to, or isolation of enriched protein from a specific cellular compartment. Many protocols in the literature and from commercially available kits claim to yield pure cellular fractions. However, in our hands, the former often do not work effectively and the latter may be prohibitively expensive if a large number of fractionations are required. Furthermore, the largely proprietary composition of reagents in commercial kits means that the user is not able to make adjustments if, for example, a particular component affects the activity of a protein of interest. The method described here allows the isolation of purified proteins from three cellular fractions: the cytosol, membrane-bound organelles, and the nucleus. It uses gentle buffers with increasing detergent strength that sequentially lyse the cell membrane, organelle membranes and finally the nuclear membrane.•Quick, simple to replicate or adjust; this method does not require expensive reagents or use of commercial kits•The protocol can be applied to tissue samples or cultured cells without changing buffer components•Yields purified fractions of cytosolic, membrane bound and nuclear proteins, with the proper distribution of the appropriate subcellular markers: GAPDH, VDAC, SERCA2 and lamin A/C.
Diaphragm formation and pressure sensitivity in batch-fabricated silicon pressure sensors (1978)

The formation of thin silicon diaphragms for batch-fabricated pressure sensors is examined. Several anisotropic silicon etchants are compared with respect to their etch rates and the surface finishes produced. Concentrated potassium hydroxide and ethylene diamine-pyrocatechol are found to be most compatible with sensor requirements. Both V-groove and boron etch-stop techniques are capable of controlling diaphragm thickness to within one micron or better, the latter removing wafer taper as a major source of variability. The effects of several process-induced diaphragm irregularities on the pressure sensitivities of piezoresistive and capacitive structures are examined using a finite-difference computer program. Diaphragm thickness is the most important parameter influencing pressure sensitivity in these structures, with resistor-diaphragm alignment and plate separation important secondary parameters in piezoresistive and capacitive devices, respectively.
On-Line Analysis of Exercise Electrocardiograms (1975)

Computer assisted interpretation of exercise electrocardiograms (XECGs) is generally expected to improve the value of exercise testing for detection of ischemic heart disease (IHD) in patients with normal resting ECGs. There are several reasons for this:
Design and Analysis of a Variable Stiffness Mechanism (2010)

The design and analysis of a mechanism with variable stiffness is examined. The mechanism, which is a simple arrangement of two springs, a lever arm and a pivot bar, has an effective stiffness that is a rational function of the horizontal position d of the pivot. The external pure force acting on the system is constrained to always remain vertical. The effective stiffness is varied by changing d while keeping the point of application of the external load constant. The expression for the effective stiffness is derived. A reverse analysis is also carried out on the mechanism. Special design cases are considered. The dynamic equation of the system is derived and used to deduce the natural frequency of the mechanism from which some insights were gained on the dynamic behavior of the mechanism.
Battlefield trauma care then and now (2012)

Butler, Frank K. Jr. MD, CAPT, MC, USN (Ret); Blackbourne, Lorne H. MD, COL, MC, USA Author Information
Quality and Knowledge in Software Engineering (1993)

Celite Corporation and Andersen Consulting have developed an advanced approach to traditional software development entitled the Application Software Factory (ASF). The approach is an integration of technology and Total Quality Management techniques which includes the use of an expert system to guide module design and perform module programming. The expert system component is called the Knowledge Based Design Assistant (KBDA) and its inclusion in the Application Software Factory Methodology has significantly reduced module development time, training time, and module and communication errors.
Characterization of the Association of the Actin-binding Protein, IQGAP, and Activated Cdc42 with Golgi Membranes (1998)

IQGAP is a recently identified actin-binding protein, which is a putative target for the Cdc42 and Rac GTP-binding proteins. Cdc42 was localized to the Golgi (Erickson, J. W., Zhang, C., Kahn, R. A., Evans, T., and Cerione, R. A. (1996) J. Biol. Chem. 271, 26850-26854), and here we show by immunofluorescence that IQGAP has a perinuclear localization, that it can be co-immunoprecipitated with Cdc42 from Golgi-enriched fractions, and that purified Golgi membranes are recognized by specific antibodies raised against IQGAP and Cdc42 in negative-stain immunogold electron microscopy experiments. Addition of activated, recombinant Cdc42 or solubilization of endogenous Cdc42 from Golgi membranes by the Rho-GDP dissociation inhibitor protein fails to solubilize IQGAP, suggesting that it associates with these membranes in a Cdc42-independent manner. Detergent solubilization of Golgi membranes leaves IQGAP and actin in an insoluble pellet but releases Cdc42 to the supernatant, whereas treatments that release actin from this detergent-insoluble pellet also release IQGAP. Addition of the COOH-terminal half of the IQGAP protein, which contains the Cdc42-binding domain, removes Cdc42 from Golgi membranes in a dose-dependent manner. These data suggest that IQGAP and Cdc42 are part of a cytoskeletal complex in Golgi membranes that may mediate Cdc42-regulated effects on the actin cytoskeleton in these membranes.
Effect of substituents on the hydrolysis of substituted phenyl .BETA.-acetylglucosaminides by bovine liver .BETA.-acetylglucosaminidase. (1976)

Michaelis constant, Km and relative catalytic constant, krelcatwere determined for the β-acetylglucosaminidase-catalyzed hydrolysis of a series of substituted phenyl β-acetylglucosaminides ; the substituents are 2, 4-dinitro, p-nitro, 4-nitro-3-methyl, m-nitro, p-chloro, m-chloro, p-methyl, m-methyl, p-methoxy and p-hydroxyl groups. The values were evaluated in terms of the ρ-σ relationship of Hammett. Plots of log Km with respect to Hammett substituent constant, σ and Hansch substituent constant, π showed the enzyme-substrate affinity to be dependent on the electronic nature of the substituents (ρ=-0.42, correlation coefficient γ=0.943) but not on the hydrophobic nature. The log krelcat value was only slightly dependent on σ value (ρ=+0.16, γ=0.626). An experiment on nucleophilic competition with methanol was carried out in an attempt to explain the small ρ value for krelcat. Methanol competes with water for the glycosyl enzyme to some extent but does not increase krelcat for the glycosides examined, indicating that the deglycosylation is not rate-limiting and hence the ρ value for krelcat pertains to the reaction of glycoside bond cleavage.
Efficient linearisation of sigma-delta modulatorsusing single-bit dither (1995)

Idle tones and noise modulation in higher-order sigma-delta modulators (SDMs) can be eliminated using single-bit dither signals, with no additional reduction in dynamic range compared to multilevel dither signals. Unlike multilevel dither, single-bit dither is easily implemented in sigma-delta analogue-to-digital converters (ADCs).
Proposal of Mark Flow Graph for Discrete System Control (1984)

The authors propose the Mark Flow Graph for the purpose of theoretical systematization of the sequential control.Sequential control systems are regarded as the event-conditon systems which are activated by mutual connections between events and conditions. These systems have such fundamental features as asynchronism, ordering, concurrency and conflict, and unsafeness and deadlock will happen to them. Petri net is one of the effective means to represent the systems with these properties and phenomena.The authors modify the concept of Petri net to develop the design and analysis tool for sequential control systems taking the safeness and notation of input/output functions into consideration. Mark Flow Graph (MFG) is proposed as such a new kind of graph. The paper deals mainly with the definitions and rules of MFG, and also with the basic subjects about its structure, structual properties and deadlock phenomenon.
Human Immunodeficiency Virus Type 1 Vpr-Dependent Cell Cycle Arrest through a Mitogen-Activated Protein Kinase Signal Transduction Pathway (2005)

The human immunodeficiency virus type 1 (HIV-1) Vpr protein has important functions in advancing HIV pathogenesis via several effects on the host cell. Vpr mediates nuclear import of the preintegration complex, induces host cell apoptosis, and inhibits cell cycle progression at G(2), which increases HIV gene expression. Some of Vpr's activities have been well described, but some functions, such as cell cycle arrest, are not yet completely characterized, although components of the ATR DNA damage repair pathway and the Cdc25C and Cdc2 cell cycle control mechanisms clearly play important roles. We investigated the mechanisms underlying Vpr-mediated cell cycle arrest by examining global cellular gene expression profiles in cell lines that inducibly express wild-type and mutant Vpr proteins. We found that Vpr expression is associated with the down-regulation of genes in the MEK2-ERK pathway and with decreased phosphorylation of the MEK2 effector protein ERK. Exogenous provision of excess MEK2 reverses the cell cycle arrest associated with Vpr, confirming the involvement of the MEK2-ERK pathway in Vpr-mediated cell cycle arrest. Vpr therefore appears to arrest the cell cycle at G(2)/M through two different mechanisms, the ATR mechanism and a newly described MEK2 mechanism. This redundancy suggests that Vpr-mediated cell cycle arrest is important for HIV replication and pathogenesis. Our findings additionally reinforce the idea that HIV can optimize the host cell environment for viral replication.
Multiresponsive Supramolecular Nanogated Ensembles (2009)

A new multiresponsive supramolecular nanogated ensemble has been developed by introducing beta-cyclodextrin (beta-CD) into polymer-grafted mesoporous silica. The cross-linked polymer produced by host-guest interaction between beta-CD and diazo-linker works as a gatekeeper to control the release of trapped molecules from hybrid materials. The presence of UV light, alpha-CD, or disulfide reducing agent can effectively open the polymeric network and release the loading with different dynamics.
Organische Bindemittel zum Wärmearmen Fügen (1972)

Abstract Die Anwendung von Klebstoffen fand weite Verbreitung, seit als Basissubstanzen synthetische organische Hochpolymere zur Verfügung standen, die physikalisch oder chemisch härten. Sie gewährleisten ausreichende Haftfähigkeit an den unterschiedlichsten Werkstoffen, Verformbarkeit und mechanische Eigenschaften auch bei erhöhten Temperaturen. Einen besonderen Fortschritt bedeuten chemisch oder mechanisch blockierte Polymersysteme, die kurze Härtungszeiten und geringen Aufwand an Fixiervorrichtungen zulassen.