gebhart/patrepeval huggingface dataset:
31.2: Light Emitting Polymers For Full Colour Display Applications (2001)

Abstract The latest developments in light emitting polymer (LEP) technology at CDT continues to show steady progress. Device performance is described for blue, green and red systems as well as a high performance yellow system in terms of device efficiency and stability. Some of the issues associated with the commercialisation of LEP technology including the development, of direct patterning techniques enabling full colour passive and active matrix display will be presented.
Synthesis of 7-Substituted 5,6-Dimethyl-2,4-dioxo-1,2,4,7-tetrahydropyrrolo[2,3-<i>d</i>][1,3]oxazines (1985)

The title compounds 2 are prepared by the cyclization of substituted pyrroles 3 with phosgene in refluxing tetrahydrofuran. In the case of 3a, it is shown that the cyclization can also be achieved after alkylation to give 8.
<i>Chlamydia pneumoniae</i> and Cardiovascular Disease (1998)

Chlamydia pneumoniae is a ubiquitous pathogen that causes acute respiratory disease. The spectrum of C. pneumoniae infection has been extended to atherosclerosis and its clinical manifestations. Seroepidemiologic studies have associated C. pneumoniae antibody with coronary artery disease, myocardial infarction, carotid artery disease, and cerebrovascular disease. The association of C. pneumoniae with atherosclerosis is corroborated by the presence of the organism in atherosclerotic lesions throughout the arterial tree and the near absence of the organism in healthy arterial tissue. C. pneumoniae has also been isolated from coronary and carotid atheromatous plaques. To determine whether chronic infection plays a role in initiation or progression of disease, intervention studies in humans have been initiated, and animal models of C. pneumoniae infection have been developed. This review summarizes the evidence for the association and potential role of C. pneumoniae in cardiovascular disease.
Daunomycin. I. The Structure of Daunomycinone (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDaunomycin. I. The Structure of DaunomycinoneF. Arcamone, G. Franceschi, P. Orezzi, G. Cassinelli, Wanda. Barbieri, and Rosanna. MondelliCite this: J. Am. Chem. Soc. 1964, 86, 23, 5334–5335Publication Date (Print):December 1, 1964Publication History Published online1 May 2002Published inissue 1 December 1964https://pubs.acs.org/doi/10.1021/ja01077a059https://doi.org/10.1021/ja01077a059research-articleACS PublicationsRequest reuse permissionsArticle Views337Altmetric-Citations126LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Autologous bone marrow transplantation for B cell malignancies after in vitro purging with floating immunobeads. (1990)

We report here 16 autologous bone marrow transplantations (ABMT) for poor prognosis B or pre-B malignancies (16 acute lymphoblastic leukemias (ALL), three Burkitt lymphomas, one multiple myeloma) in 11 adults and five children where in vitro purging was accomplished by means of floating immunobeads. This method was developed to avoid non-specific killing by complement or toxin or batch-to-batch variability and provides a 3 log reduction of tumor in a model of B lymphoid malignancies. Low density bone marrow mononuclear cells were incubated for 30 min at 4 degrees C with anti CD10 (ALB2 Immunotech) and/or anti CD19 (Bg4) monoclonal antibodies (MoAb) and then mixed with low density polypropylene beads precoated with a rat antimouse MoAb. After 1 h at 4 degrees C the beads with target cells were decanted; the depleted marrow was collected through a microfilter and cryoperserved. After immunodepletion the recovery of nucleated cells was 75% with a median of 0.75 x 10(8) cells/kg (range 0.3-3.6) and the recovery of hematopoietic progenitors was 83% with a median of 2.9 x 10(4) CFU-GM/kg. The conditioning regimen consisted of busulfan 16 mg/kg and melphalan 140 mg/m2 for three patients, fractionated total body irradiation (TBI) following melphalan 140 mg/m2 for nine patients, TBI and cyclophosphamide 120 mg/m2 for two patients and TBI associated with melphalan and cyclophosphamide for two patients.(ABSTRACT TRUNCATED AT 250 WORDS)
Information diffusion in online social networks (2013)

Online social networks play a major role in the spread of information at very large scale. A lot of effort have been made in order to understand this phenomenon, ranging from popular topic detection to information diffusion modeling, including influential spreaders identification. In this article, we present a survey of representative methods dealing with these issues and propose a taxonomy that summarizes the state-of-the-art. The objective is to provide a comprehensive analysis and guide of existing efforts around information diffusion in social networks. This survey is intended to help researchers in quickly understanding existing works and possible improvements to bring.
Splenic uptake of immune complexes in man is complement-dependent. (1993)

We have examined the effects of hereditary homozygous C2 deficiency on the processing of radiolabeled soluble immune complexes (IC). A patient with C2 deficiency was studied before and after treatment with fresh frozen plasma (FFP). Hepatitis B surface Ag (HBsAg):anti-HBsAg immune complexes were prepared in vitro using Ag radiolabeled with 123I, and injected intravenously. Dynamic and static gamma-scintigraphy was performed to delineate the sites and kinetics of complex clearance. The patient was initially studied when her C2 level and CH50 were zero, and again 1 wk later after treatment with 12 units of FFP, which normalized these parameters. Before treatment there was rapid uptake of complexes by the liver (t90% [time for 90% uptake] = 13.6 min) and rapid clearance from the circulation (t1/2 = 6.8 min). No splenic uptake was detected, and there was no binding of complexes to erythrocyte CR1. Between 30 and 60 min there was release of 11% of the tracer from the liver. In the second study, performed after normalization of classical pathway complement activity, the t1/2 of IC clearance increased to 9.8 min, and t90% was 27 min. Twenty percent of injected complexes now localized to the spleen, and there was no longer any release of complexes between 30 and 60 min. The kinetics of IC processing and the sites of uptake in this posttherapy study were closely similar to two normal subjects studied in parallel, with a maximum of 72% of injected complexes binding to erythrocytes. These observations indicate that the uptake of immune complexes in the spleen in humans is complement-dependent, and suggest that the observed predisposition to SLE in patients with complement deficiency may be related to abnormal processing of immune complexes.
[Paper] A 1/1.7-inch 20Mpixel Back-Illuminated Stacked CMOS Image Sensor with Multi-Functional Modes (2016)

We have developed a 1/1.7-inch 20Mpixel back-illuminated stacked CMOS image sensor with multi-functional modes which are parallel multiple sampling, the two simultaneous output streams and data compression. This sensor has achieved a RMS random noise of 1.3e- with the parallel multiple sampling and the two simultaneous output streams of 4Mpixel for a movie mode and 16Mpixel for a still mode with a 2.3Gb/s/lane high-speed interface. Moreover, the high speed output mode of 16Mpixel at 120fps with a low image degradation compression. The stacked structure realizes on an analog implementation of the double column parallel ADCs.
Processual Management Using Intelligent Workflow Systems (1999)

During the late 1990s it has become generally accepted in business that process (as opposed to functional) management is an essential element of world-class management. In an increasingly competitive environment, the role of the human manager has been challenged by sophisticated case handling and management systems, variously known as workflow automation, workflow systems and workflow management systems. To date, most of these systems have been implemented to reduce routine clerical and administrative work. They have been seen as a means of automating manual systems and to assist the implementation of Business Process Reengineering. This paper discusses current research into the use of software agents to enhance workflow systems; to provide additional functionality and flexibility; and to address human factors such as individual abilities and preferences. INTRODUCTION Huffmeijer [4] suggested that a workflow is &quot;a system whose elements are activities, related to one another by a trig...
Femtosecond fiber-feedback optical parametric oscillator (2001)

We demonstrate what is to our knowledge the first synchronously pumped high-gain optical parametric oscillator (OPO) with feedback through a single-mode fiber. This device generates 2.3-2.7 W of signal power in 700-900-fs pulses tunable in a wavelength range from 1429 to 1473 nm. The necessary high gain was obtained from a periodically poled LiTaO(3) crystal pumped with as much as 8.2 W of power at 1030 nm from a passively mode-locked Yb:YAG laser with 600-fs pulse duration and a 35-MHz repetition rate. The fiber-feedback OPO setup is compact because most of the resonator feedback path consists of a standard telecom fiber. Because of the high parametric gain, the fiber-feedback OPO is highly insensitive to intracavity losses. For the same reason, the synchronization of the cavity with the pump laser is not critical, so active stabilization of the cavity length is not required.
Inorganic Coördination Polymers. V. The Use of Neutral Ligands (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInorganic Coördination Polymers. V. The Use of Neutral LigandsB. P. Block and Joseph SimkinCite this: Inorg. Chem. 1963, 2, 4, 688–690Publication Date (Print):August 1, 1963Publication History Published online1 May 2002Published inissue 1 August 1963https://pubs.acs.org/doi/10.1021/ic50008a004https://doi.org/10.1021/ic50008a004research-articleACS PublicationsRequest reuse permissionsArticle Views63Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Reflection of Sound from a Surface of Saw-Tooth Profile (1957)

A variational method is used to calculate the energy diffracted into the various orders produced when a plane acoustic wave is incident on a periodic, pressure-release surface of saw-tooth shape. The results of companion experiments performed with a cork-covered surface, using techniques of underwater sound are also presented. The relative energies reflected in various orders are plotted as a function of the ratio of acoustic wavelength to spatial period of the surface for a range of angles of incidence. Theory and experiment agree within 10% for all angles of incidence examined and for a large part of the frequency range covered.
Colouration in assisted reverberation systems (2002)

Assisted reverberation systems are used to electronically enhance the reverberation time of an auditorium. A limitation of such systems is that they produce enhanced room transfer functions that contain unnaturally large peaks. These peaks produce colouration of the sound decay. A stochastic simulation technique is presented that quantifies colouration by measuring the probability density function of the transfer functions and comparing it with the ideal Rayleigh distribution of an unassisted room. The technique is applied to existing reverberation systems, and to a new system which provides large increases in reverberation time without increasing the loop gain. It is shown that, for the same power gain, the new system produces a higher colouration, but that this problem may be eliminated by the use of an allpass reverberator.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Clinical Plan for MDMA (Ecstasy) in the Treatment of Posttraumatic Stress Disorder (PTSD): Partnering with the FDA (2002)

The FDA and the Spanish Ministry of Health have concluded that the risk/benefit ratio is favorable under certain circumstances for clinical studies investigating MDMA-assisted psychotherapy. Both agencies have approved pilot studies in chronic posttraumatic stress disorder (PTSD) patients who have failed to obtain relief from at least one course of conventional treatment. These studies, the only ones in the world into the therapeutic use of MDMA, are being funded by a nonprofit research and educational organization, the Multidisciplinary Association for Psychedelic Studies (MAPS, www.maps.org). A rationale is offered explaining why MAPS chose to focus its limited resources on MDMA, and also on PTSD patients. A Clinical Plan is elaborated for the conduct of the "adequate and well-controlled" trials necessary to evaluate the safety and efficacy of MDMA-assisted psychotherapy for PTSD, with the studies estimated to cost about 5 million dollars and to take about five years. The Clinical Plan has been developed, in part, through analysis of the studies conducted by Pfizer in its successful effort to have Zoloft approved by the FDA for use with PTSD patients, and through review of transcripts of the FDA's Psychopharmacologic Drugs Advisory Committee meeting that recommended approval of Zoloft for PTSD.
Contextual Action Recognition with R*CNN (2015)

There are multiple cues in an image which reveal what action a person is performing. For example, a jogger has a pose that is characteristic for jogging, but the scene (e.g. road, trail) and the presence of other joggers can be an additional source of information. In this work, we exploit the simple observation that actions are accompanied by contextual cues to build a strong action recognition system. We adapt RCNN to use more than one region for classification while still maintaining the ability to localize the action. We call our system R*CNN. The action-specific models and the feature maps are trained jointly, allowing for action specific representations to emerge. R*CNN achieves 90.2% mean AP on the PASAL VOC Action dataset, outperforming all other approaches in the field by a significant margin. Last, we show that R*CNN is not limited to action recognition. In particular, R*CNN can also be used to tackle fine-grained tasks such as attribute classification. We validate this claim by reporting state-of-the-art performance on the Berkeley Attributes of People dataset.
Non-antiarrhythmic agents for prevention of postoperative atrial fibrillation: role of statins (2007)

Perioperative statin therapy may represent an important non-antiarrhythmic, adjunctive therapeutic strategy for the prevention of postoperative atrial fibrillation.
Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells prevents its surface expression and associated function. (1993)

Although mouse interleukin-3-dependent, bone marrow culture-derived progenitor mast cells (BMMC) and a Kirsten sarcoma virus (KiSV)-immortalized mouse mast cell line (MC4w) both express on their surfaces receptors for the Fc portion of IgG (Fc gamma R), only MC4w degranulate upon Fc gamma R perturbation. As shown by surface iodination and SDS-polyacrylamide gel electrophoresis analysis of deglycosylated proteins immunoprecipitated with the Fc gamma R-specific monoclonal antibody 2.4G2, a 26-kDa protein, identified as Fc gamma RIII by immunoblotting with antibody to Fc gamma RIII, was predominantly expressed on the surface of MC4w but minimally on BMMC. However, both BMMC and MC4w expressed mRNA for Fc gamma RIII as determined by RNA blot analysis, and both translated Fc gamma RIII as assessed by intrinsic radiolabeling and SDS-polyacrylamide gel electrophoresis analysis of deglycosylated monoclonal antibody 2.4G2 immunoprecipitates. Pulse-chase analysis showed that intrinsically radiolabeled Fc gamma RIII was stable in MC4w cells but was degraded rapidly in BMMC and that newly synthesized Fc gamma RIII remained sensitive to digestion by endoglycosidase H in BMMC but rapidly became resistant in MC4w. These data suggest that the deficiency in surface Fc gamma RIII expression on BMMC is due to the degradation of Fc gamma RIII in the endoplasmic reticulum. Immunoprecipitation of surface Fc gamma R and Fc receptors for IgE (Fc epsilon RI) from digitonin-extracted cells followed by immunoblotting with antibody to Fc epsilon RI gamma-chain showed that gamma-chain is associated with surface Fc epsilon RI and Fc gamma R in MC4w, but only with Fc epsilon RI in BMMC, which lack surface Fc gamma RIII. Inasmuch as BMMC are progenitors of serosal mast cells, which, like MC4w, express surface Fc gamma RIII and undergo Fc gamma R-mediated activation, the data suggest that maturation of BMMC enables Fc gamma RIII to bypass degradation in the endoplasmic reticulum, resulting in the acquisition of functional Fc gamma RIII/gamma-chain complexes on the cell surface.
Fontan-Associated Liver Disease (2020)

Surgical innovation and multidisciplinary management have allowed children born with univentricular physiology congenital heart disease to survive into adulthood. An estimated global population of 70 000 patients have undergone the Fontan procedure and are alive today, most of whom are <25 years of age. Several unexpected consequences of the Fontan circulation include Fontan-associated liver disease. Surveillance biopsies have demonstrated that virtually 100% of these patients develop clinically silent fibrosis by adolescence. As they mature, there are increasing reports of combined heart-liver transplantation resulting from advanced liver disease, including bridging fibrosis, cirrhosis, and hepatocellular carcinoma, in this population. In the absence of a transplantation option, these young patients face a poor quality of life and overall survival. Acknowledging that there are no consensus guidelines for diagnosing and monitoring Fontan-associated liver disease or when to consider heart transplantation versus combined heart-liver transplantation in these patients, a multidisciplinary working group reviewed the literature surrounding Fontan-associated liver disease, with a specific focus on considerations for transplantation.
Graphene-Based Three-Dimensional Hierarchical Sandwich-type Architecture for High-Performance Li/S Batteries (2013)

A multiwalled carbon nanotube/sulfur (MWCNT@S) composite with core-shell structure was successfully embedded into the interlay galleries of graphene sheets (GS) through a facile two-step assembly process. Scanning and transmission electron microscopy images reveal a 3D hierarchical sandwich-type architecture of the composite GS-MWCNT@S. The thickness of the S layer on the MWCNTs is ~20 nm. Raman spectroscopy, X-ray diffraction, thermogravimetric analysis, and energy-dispersive X-ray analysis confirm that the sulfur in the composite is highly crystalline with a mass loading up to 70% of the composite. This composite is evaluated as a cathode material for Li/S batteries. The GS-MWCNT@S composite exhibits a high initial capacity of 1396 mAh/g at a current density of 0.2C (1C = 1672 mA/g), corresponding to 83% usage of the sulfur active material. Much improved cycling stability and rate capability are achieved for the GS-MWCNT@S composite cathode compared with the composite lacking GS or MWCNT. The superior electrochemical performance of the GS-MWCNT@S composite is mainly attributed to the synergistic effects of GS and MWCNTs, which provide a 3D conductive network for electron transfer, open channels for ion diffusion, strong confinement of soluble polysulfides, and effective buffer for volume expansion of the S cathode during discharge.
Critical residues involved in FMN binding and catalytic activity in cytochrome P450BM-3. (1993)

Cytochrome P450BM-3 from Bacillus megaterium is a soluble, catalytically self-sufficient fatty acid mono-oxygenase that, in structural organization and amino acid sequence, resembles the Class II (microsomal) P450 systems. Its single polypeptide chain contains both a P450 heme domain and an NADPH:P450 reductase domain, each of which bears significant homology with its microsomal counterparts. We report here the critical nature of three amino acids in the reductase domain of this enzyme with respect to FMN binding and catalytic activity. We used site-directed mutagenesis to change glycine 570 to bulkier amino acids; none of these mutant enzymes contained FMN after purification. We also made substitutions for tryptophan 574 and tyrosine 536, which by sequence analogy (Porter, T. D. (1991) Trends Biochem. Sci. 16, 154-158) were proposed to bind FMN through stacking of the aromatic rings with the isoalloxazine ring of the flavin. Mutants of tryptophan 574 which retained the aromatic side chain contained no less than 0.85 mol of FMN per mol of enzyme, while aspartate and glycine substitutions yielded enzymes which did not incorporate FMN. Substitution of tyrosine 536 with aspartate gave an enzyme which contained 0.44 mol of FMN per mol of enzyme but was inactive as a fatty acid hydroxylase and had only 2% of wild-type cytochrome c reductase activity, while the glycine mutant at this position bound no FMN. Furthermore, although all of the mutant enzymes contained 1 mol of FAD per mol of enzyme, the Y536D mutant and those entirely lacking FMN retained no more than 40% of wild-type ferricyanide reductase activity. By assaying these enzymes in the presence of added FMN, we were able to assess the relative importance of the residues in the wild-type sequence with respect to their contribution to FMN binding. In addition, the aromatic mutants of tryptophan 574, which were nearly as active in cytochrome c reduction as wild-type P450BM-3, were only 20% as active in myristate hydroxylation as the wild-type enzyme, suggesting that this amino acid plays an important role in the flow of electrons between the P450 heme and reductase domains.
Very low threshold current ridge-waveguide AlGaAs/GaAs single-quantum-well lasers (1985)

Ridged-waveguide AlGaAs/GaAs single-quantum-well lasers were fabricated from a molecular-beam-grown GRIN-SCH wafer in which a superlattice buffer layer was introduced. Fabricated diodes exhibited excellent lasing characteristics including a very low threshold current of 5 mA with a T0 value as high as 160 K.