gebhart/patrepeval huggingface dataset:
Cotton Lea5 and Lea14 Encode Atypical Late Embryogenesis-Abundant Proteins (1993)

LEA proteins comprise a large group of probable desiccation protectants that in cotton (Gossypium hirsu tum) are developmentally induced during the postabscission stage of embryogenesis (Hughes and Galau, 1989) and are environmentally induced in embryos by desiccation or culture with ABA or high osmoticum (Hughes and Galau, 1991). In other plants, some Lea mRNAs are induced by similar stresses in vegetative tissues (Skriver and Mundy, 1991). Of the many Lea and water stress-related mRNAs that have been sequenced (Skriver and Mundy, 1991), a11 but cotton LealZ, cDNA D34 (Baker et al., 1988), and desiccation-induced Craterostigma cDNA pcC27-45 (Piatkowski et al., 1990) encode proteins that are very hydrophilic (Baker et al., 1988; Skriver and Mundy, 1991). Extensive hydrophilicity is expected of structural and nonstructural proteins that bind or replace water during water stress (Baker et al., 1988; Hughes and Galau, 1989), but other functions might be expected for those that are not remarkably hydrophilic. Of the 18 cloned cotton Lea and LeaA mRNAs (Galau et al., 1986), only Lea5 (cDNA D73) and Leal4 (cDNA D95) are highly induced in mature leaves of water-stressed plants or in water-stressed, detached leaves (D.W. Hughes, G.A. Galau, unpublished observations). We report here that both genes encode proteins with significant hydropathic character and that Leal4 is a homolog of the gene encoding the Craterostigma desiccationinduced cDNA pcC27-45 (Piatkowski et al., 1990). Both alloalleles of Leu5 were recovered, and 3809 nucleotides of Lea5-A clone GD73-14R and 1269 nucleotides of Lea5-D clone GD73-2R were sequenced along with several Lea5 cDNA clones (Table I). Lea5-A and Lea5-D are very similar from at least 240 nucleotides upstream of the transcription start to about 230 nucleotides 3' of the major polyadenylation site, after which they diverge in sequence. The cDNA clones D73 and D96 are transcribed from Lea5-A, and cDNA clone D122 is transcribed from Lea5-D. Clone D73 is the result of an error in excision of the single intron; instead of splicing to Lea5-A nucleotide 2515, as occurs with
Characterizing water resources and trends of sector wise water consumptions in Saudi Arabia (2013)

Understanding of water resources and trends of water consumptions is important to offer sustainable water resources management strategy. In this research, water resources and trends of water consumptions in Saudi Arabia were investigated. The non-renewable groundwater reserves were estimated to be 259.1–760.6 billion cubic meters (BCM) with an effective annual recharge of 886 million cubic meters (MCM). The total internal renewable water was estimated to be 2.4 BCM/year. Approximately 1.4 BCM/year of runoff is collected by 302 dams. The country produces approximately 1.06 BCM desalinated water annually. The wastewater treatment plants treat approximately 0.73 BCM/year of domestic wastewater from which 0.33 BCM is recycled. The water demand in 2009 was 18.51 BCM in which 83.5% were for agriculture. From 2004 to 2009, agricultural water demand was decreased by 2.5%/year, while the domestic and industrial water demands were increased by 2.1%/year and 2.2%/year, respectively. Between 1999 and 2008, domestic water subscribers were increased by 22.7%, while the annual domestic water consumption was increased from 1391 (609–2164) to 3818 (1687–7404) m3/subscriber. The industrial water demands were increased from 56 to 713 MCM/year between 1980 and 2009. Following characterization, nonlinear equations were developed to predict the domestic, industrial and agricultural water demands. The predicted water demands were within 1–10% of the historically reported values. The findings might be useful in understanding water sources, water demands and identifying new sources for sustainable water resources management.
Sensorless Control of BLDC Motor using a Hysteresis Comparator and Back EMF technique (2015)

This paper describes the brushless dc (BLDC) motor sensorless control system for hydraulic oil pump. The sensorless techniques that are based on a hysteresis comparator the basic implementation of hysteresis current control is based on deriving the switching signals from the comparison of the current and voltage method with a high starting torque are suggested. The hysteresis comparator is used to compensate for the phase delay of the back EMFs. The concept of the application is that of a drive using Back-EMF Zero Crossing technique for position detection. It prevent multiple output transitions from noise or ripple in the terminal voltages. The rotor position is aligned at standstill for maximum starting torque. Also, the stator current can be easily adjusted by modulating the pulse width of the switching devices during alignment. Some experiments are implemented on a single chip PIC controller to demonstrate the feasibility of the suggested sensorless and start-up techniques. Index Terms-Brushless dc (BLDC) motor, hysteresis comparator, sensorless control, start-up technique.
Zum Verhalten von Cobalt(II) und Eisen(III) bei der Flüssig‐Flüssig‐Extraktion mit pyridylsubstituierten Benzensulfonamiden (1982)

Abstract Als Modelle für die in der Patentliteratur empfohlenen Metallextraktionsmittel auf Sulfonamidbasis (LIX 34 u.a.) werden pyridylsubstituierte Benzensulfonamide N 3 NHSO 2 R und N 2 NHSO 2 R auf ihr komplexchemisches Verhalten gegenüber Cobalt(II) und Eisen(III) untersucht. Co(N 3 NSO 2 R) 2 hat eine stark verzerrte tetraedrische Struktur. Auf Grund der Strukturdaten wird eine π‐Rückgabebindung vom Cobalt zum Amidstickstoff diskutiert, die eine gegenüber normalen Cobalt(II)‐Komplexen erhöhte effektive Ladung des Zentralatoms erzeugt. Deshalb gelingt es unter normalen Bedingungen nicht, Co(N 3 NSO 2 R) 2 zu oxidieren, wohl aber zu reduzieren. Co(N 2 NSO 2 R) 2 ist tetramer, über Sulfonamidbrücken wird die Koordinationszahl 5 erreicht. Eisen(III) bildet die Komplexsalze [Fe(N 3 NHSO 2 R) 2 (N 3 NSO 2 R)](NO 3 ) 2 · xH 2 O und [Fe(N 2 NHSO 2 R) 2 (N 2 NSO 2 R)](NO 3 ) 2 · xH 2 O, die zum Low‐Spin‐Typ gehören und in organischen Lösungsmitteln nicht löslich sind. Darin liegt die Erklärung für den Befund, daß im Falle der Metallextraktionsmittel auf Sulfonamidbasis die Kupfer(II)‐Eisen(III)‐Trennung keine Probleme bringt.
On new species in a new earthworm genus from Puerto Rico (1970)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
A Practical Approach to the Reduction of Pseudorange Multipath Errors in a Ll GPS Receiver (1994)

The reduction of multipath biases on GPS measurements has traditionally been achieved through innovative antenna design, such as choke ring ground planes, and careful antenna site selection. These methods, although effective, are not always practical, especially in a kinematic environment. The implementation of Narrow Correlator mspacing design in GPS receiver code tracking loops has greatly reduced the multipath bias and the measurement noise on C/A code pseudorange measurements. Even with these advancements the bias due to multipath is still dominant in GPS position calculations. This paper introduces a new tracking loop which takes full advantage of the Narrow CorrelatorT5t spacing design, but in addition, is much more resistant to multipath effects on the correlation function and thereby reduces the multipath bias on the pseudorange measurements. The theory behind this new tracking loop design is presented along with its implementation into existing receiver hardware. Test results from a prototype receiver are presented. They show a 25 to 50 percent reduction of multipath error effects in the DGPS position solution as compared to a standard narrow correlator receiver.
Increased circulating adrenomedullin, a novel vasodilatory peptide, in sepsis. (1996)

Human adrenomedullin (hAM), a potent vasodilatory peptide originally identified in pheochromocytoma, has been shown to be present in various human tissues and circulate in human plasma. We measured plasma concentrations of immunoreactive hAM in patients with sepsis who had been admitted to intensive care unit (ICU). Plasma hAM concentrations in 12 septic patients upon entering the ICU were extremely elevated (107 +/- 139 fmol/ml: mean +/- SD) compared to those of 16 age-matched normal subjects (7.9 +/- 3 fmol/mL). Among 10 patients with normal renal function, plasma hAM levels either decreased or increased during the hospital course; the former group survived and the latter group succumbed. Two patients with acute renal failure had markedly elevated plasma hAM levels during the early course, which declined rapidly during the recovery course. High performance liquid chromatography of plasma extracts from one patient with acute renal failure revealed a single major component of immunoreactive hAM coeluting with authentic hAM (1-52) during acute and recovery phase. Plasma hAM concentration showed positive correlations with heart rate, right atrial pressure, and serum creatinine concentration, but not with other hemodynamic variables. These data suggest that a marked increase in circulating hAM in sepsis may be caused by its decreased clearance and/or its enhanced synthesis by multiple organ dysfunction, and that increased endogenous hAM may be involved in the mechanism of cardiovascular abnormalities associated with sepsis.
The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota (2016)

Abstract Intestinal bacteria influence mammalian physiology, but many types of bacteria are still uncharacterized. Moreover, reference strains of mouse gut bacteria are not easily available, although mouse models are extensively used in medical research. These are major limitations for the investigation of intestinal microbiomes and their interactions with diet and host. It is thus important to study in detail the diversity and functions of gut microbiota members, including those colonizing the mouse intestine. To address these issues, we aimed at establishing the Mouse Intestinal Bacterial Collection (miBC), a public repository of bacterial strains and associated genomes from the mouse gut, and studied host-specificity of colonization and sequence-based relevance of the resource. The collection includes several strains representing novel species, genera and even one family. Genomic analyses showed that certain species are specific to the mouse intestine and that a minimal consortium of 18 strains covered 50–75% of the known functional potential of metagenomes. The present work will sustain future research on microbiota–host interactions in health and disease, as it will facilitate targeted colonization and molecular studies. The resource is available at www.dsmz.de/miBC .
The application of DSRC technology in intelligent transportation system (2009)

DSRC (Dedicated Short Range Communications) technology is specially developed for vehicle-to-vehicle and vehicle-to-infrastructure communication in Intelligent Transportation System (ITS). Compared to other wireless communication technologies, DSRC technology has many advantages. This paper discusses the technical characteristics, communication mechanism, and the application of DSRC technology in ITS.
THE ROLE AND PERFORMANCE OF THIRD PARTIES IN THE SOUTH AUSTRALIAN PLANNING SYSTEM (1984)

(1984). THE ROLE AND PERFORMANCE OF THIRD PARTIES IN THE SOUTH AUSTRALIAN PLANNING SYSTEM. Australian Planner: Vol. 22, No. 4, pp. 21-24.
The prion gene is associated with human long-term memory (2005)

Human cognitive processes are highly variable across individuals and are influenced by both genetic and environmental factors. Although genetic variations affect short-term memory in humans, it is unknown whether genetic variability has also an impact on long-term memory. Because prion-like conformational changes may be involved in the induction of long-lasting synaptic plasticity, we examined the impact of single-nucleotide polymorphisms (SNPs) of the prion protein gene (PRNP) on long-term memory in healthy young humans. SNPs in the genomic region of PRNP were associated with better long-term memory performance in two independent populations with different educational background. Among the examined PRNP SNPs, the common Met129Val polymorphism yielded the highest effect size. Twenty-four hours after a word list-learning task, carriers of either the 129MM or the 129MV genotype recalled 17% more information than 129VV carriers, but short-term memory was unaffected. These results suggest a role for the prion protein in the formation of long-term memory in humans.
CCAAT/enhancer binding protein expression is rapidly extinguished in TA1 adipocyte cells treated with tumor necrosis factor. (1992)

Tumor necrosis factor (TNF) has been shown to have diverse effects on a wide variety of cell types. In the mouse adipogenic TA1 cell line, TNF completely abolishes differentiation and reverts fully differentiated fat cells into fibroblasts. This block in differentiation and its reversal is due to the rapid reduction in the expression of adipose-specific genes. This study reports that the transcription factor, CCAAT/enhancer binding protein (C/EBP), previously reported to promote the differentiation of 3T3-L1 adipocytes, is expressed in TA1 cells. During their growth in culture, the levels of C/EBP, as evidenced by its cellular levels of specific mRNA, protein, and DNA binding activity, increase dramatically when cells reach confluence and proceed to differentiate. Addition of TNF to cultured preadipocytes or fully differentiated adipocytes rapidly reduces C/EBP levels and is accompanied by the decrease in expression of adipose-specific genes. C/EBP binding sites occur in several adipose-specific genes, and here it is demonstrated that its presence in a novel adipose-specific gene, Clone 47, also referred to as FSP27, may be responsible for the strong down-regulation of the expression of the Clone 47 (FSP27) promoter-linked chloramphenicol acetyl transferase gene by TNF. This study proposes that the loss of C/EBP in response to TNF treatment may in part explain the loss of the adipocyte differentiated state.
임상연구 : 초기 자궁경부암 근치적자궁적출술 후 치료실패 고위험 환자군에서 보조적 항암화학방사선요법의 역할 (2000)

목적 : 초기 자궁경부암(병기 IA2, IB, IIA) 환자에서 근치적자궁적출술과 골반림프절절제술 후에 치료실패율이 높은 고위험군에게 보조적 동시 항암화학방사선요법(GOG #109 protocol)에 따른 치료의 효용성을 알아보고자 하였다.연구방법 : 1994년 7월부터 1997년 6월까지 만 3년간 아주대학교 병원에서 초기 자궁경부암으로 진단 받고, 근치적자궁적출술 및 골반림프절 절제술을 시행한 63명의 환자 중에서 암세포의 골반림프절 전이, 자궁방 또는 절단면 침윤을 보인 15명을 대상으로 보조적 동시 항암화학방사선요법을 시행하고 치료효과를 전향적으로 임상 분석하였다. 보조적 치료는 수술 후 2-3주 이내에 항암화학치료로 시작하였으며 매 4주마다 총 4주기를 시행하였고, 치료 제 1일에 cisplatin 75mg/m2, 2일에서 5일까지 5-FU(1000mg/m2/d)를 주사하였다. 2주기 및 3주기 항암화학치료는 5주간의 방사선 치료와 같이 병용하였다.같은 기간동안 근치적자궁적출술과 골반림프절절제술 후에 재발 고위험 인자와 관계없이 추가 치료를 시행하지 않은 48명을 대조군으로 하여 재발율과 생존율을 비교 평가하였다. 치료 종료 후 추적 관찰 기간은 최소 24개월에서 51개월까지로 평균 37.3개월이었다.결과 : 전체 63명의 대상 환자 중에서 3명(4.8%)이 재발하였으며 이들은 모두 대조군으로 치료군과는 통계학적 차이가 없었다(p>0.05). 추적 관찰 중 환자 사망은 없었으며 무병생존율(relapse-free survival rate)은 치료군에서 100%, 대조군에서 93.8%로 이들간의 통계학적 차이는 없었다(p>0.05).결론 : 본 연구의 결과 근치적 수술 후 치료실패율이 높은 예후인자를 가진 자궁경부암 환자군에서 modified GOG #109 protocol에 준한 보조적 치료를 함으로써 재발율 및 무병생존율을 대조군과 유사한 수준으로 향상시킬 수 있을 것으로 생각된다.
Static Analysis of Model Transformations for Effective Test Generation (2012)

Model transformations are an integral part of several computing systems that manipulate interconnected graphs of objects called models in an input domain specified by a metamodel and a set of invariants. Test models are used to look for faults in a transformation. A test model contains a specific set of objects, their interconnections and values for their attributes. Can we automatically generate an effective set of test models using knowledge from the transformation? We present a white-box testing approach that uses static analysis to guide the automatic generation of test inputs for transformations. Our static analysis uncovers knowledge about how the input model elements are accessed by transformation operations. This information is called the input metamodel footprint due to the transformation. We transform footprint, input metamodel, its invariants, and transformation pre-conditions to a constraint satisfaction problem in Alloy. We solve the problem to generate sets of test models containing traces of the footprint. Are these test models effective? With the help of a case study transformation we evaluate the effectiveness of these test inputs. We use mutation analysis to show that the test models generated from footprints are more effective (97.62% avg. mutation score) in detecting faults than previously developed approaches based on input domain coverage criteria (89.9% avg.) and unguided generation (70.1% avg.).
Composite conduction in ion-implanted polymers (1993)

The temperature dependence of the dc conductivity for polyamide-imide films, implanted with 50 keV As ions to different fluences, has been studied. Our high-resolution data reveal a two-component conductivity that depends on both one-dimensional variable range hopping (VRH) and three-dimensional VRH. For low fluence levels (5×1015 ions/cm2), the one-dimensional VRH is dominant while at higher fluences (1×1017 ions/cm2), the three-dimensional VRH dominates. These materials become highly disordered and form hard carbon materials along the ion track. The conductivity may be explained by 1D VRH along the ion track at low fluences while at higher fluences, regions of carbon rich material form three-dimensional structures where 3D VRH exists. This rather simple model and its composite conductivity can explain the exact curvature of the temperature dependent conductivity, while single VRH models and percolation models cannot.
Using peripheral blood mRNA signature to distinguish between breast cancer and benign breast disease in non-conclusive mammography patients (2010)

Due to the small volume and high density of breast tissue in Asian women, particularly younger women, mammographic diagnosis is sometimes non-conclusive, with a Breast Imaging Reporting and Data System (BI-RADS) result of 0. No alternative based on blood biomarkers has yet succeeded in discriminating between patients with breast cancer (BC) and those with benign breast disease (BBD) among BI-RADS 0 patients. In our study, 84 BC and 94 BBD patients with mammographic results and confirmed pathologic information were enrolled and categorized into two groups, namely, 79 BC and 73 BBD patients with BI-RADS 1-5 and 5 BC and 21 BBD patients with BI-RADS 0. RNA extracted from peripheral blood samples collected in PAXgene (TM) tubes was analyzed after NuGEN WT-Ovation (TM) RNA amplification using Affymetrix GeneChip.
An Intelligent High-Speed 3D Data Registration Integrated Circuit Applied to Large Array Format Inkjet Printhead (2006)

A novel architecture of high-selection-speed 3D data registration for inkjet application is proposed in this paper. As the increasing demand on the requirement of printing speed and simplicity of data management, inkjet printheads have been extended in the nozzle numbers from tens to hundreds in the recent years and further to thousands in the future, while intending to maintain data accessing points in the order of 20-40. 3 dimensional data registration scheme to reduce the number of data accessing points as well as the scanning lines for large array inkjet printhead with nozzle number more than 1000. This IC architecture involves three dimension multiplexing with the provision of a gating transistor for each ink firing resistor, whereby current to an ink firing resistor flows only when its associated gating transistor is selected. Three signals, including selection (S), address (A), and power supply (P), will be employed together to activate a nozzle for droplet ejection. The total numbers of data accessing points will be X = 3 times <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> radicY + 1 all of the jets of the printhead are controlled by 5 input lines with multiplexer data latches and shift registers. The scanning time is reduced up to 30% (the scanning speed is also increased by 3 folds) thanks to the great reduction of the lines for scanning. This device has been designed, fabricated by CMOS 0.35 mum process, and characterized. Experiment results demonstrated the functionality of the fabricated IC in operation, signal transmission and control more than 1000 nozzles with a 5 pl. ink drop volume
Physical-layer security in stochastic wireless networks (2008)

Motivated by recent developments in physical-layer security and stochastic geometry, we aim to characterize the fundamental limits of secure communication in wireless networks. Based on a general model in which legitimate nodes and potential eavesdroppers are randomly scattered in space, we define the secure communication graph (s-graph) from the point of view of information-theoretic security. For the Poisson s-graph, we provide conclusive results for: (a) the in-degree and out-degree of a node; (b) the isolation probability; and (c) the secrecy capacity between a node and each of its neighbours. Our analysis reveals the innate connections between information-theoretic security and the spatial densities of legitimate and eavesdropper nodes.
Glycosylation, an effective synthetic strategy to improve the bioavailability of therapeutic peptides (2016)

Glycosylation of peptides is a promising strategy for modulating the physicochemical properties of peptide drugs and for improving their absorption through biological membranes. This review highlights various methods for the synthesis of glycoconjugates and recent progress in the development of glycosylated peptide therapeutics. Furthermore, the impacts of glycosylation in overcoming the existing barriers that restrict oral and brain delivery of peptides are described herein.
Effect of Cognate Human CD4+ T Cell and Endothelial Cell Interactions Upon Chemokine Production (2004)

Cognate interactions between alloreactive CD4+ T cells and MHC class II-expressing EC results in a specific pattern of chemokine production. These chemokines could play important roles in recruitment of leukocytes into vascularised allografts.
The Effectiveness of Music Therapy System for the Elderly with Mild Cognitive Impairment (2019)

Every human being must experience aging eventually. The global population aged 60 years or over was 962 million in 2017. It is expected the number of seniors will be approximately 2.1 billion in 2050 (United Nation, 2017). With the increasing number of elderly, the number of senior adults with MCI (mild cognitive impairment) and early-stage dementia is rising as well. Aging is a worldwide problem and many countries are preparing hard to cope with it. Music therapy has proven to be an effective method to decrease the development of dementia as well as enhancing the behavior and cognitive abilities of seniors. A music therapy system was developed in this study for the elderly especially with MCI. The system is a kind of meaningful game for music therapy. Product designers and ergonomists have designed and redesigned the system. This music therapy system was chosen to be developed after conducting a survey. A specific instrument was selected and an usability test was conducted with a functional prototype. Before deciding the product design, an ergonomic pilot study was performed with a paper mock-up. Ten functional prototypes of the music therapy system were finally produced for a 10 week clinical test. The clinical test was performed in a dementia center and the results showed music therapy was effective for the elderly with MCI. The performance of the senior participants was also analyzed to examine their behavioral reactive abilities.
Risk Assessment of Information Technology Systems (2009)

An international association advancing the multidisciplinary study of informing systems. Founded in 1998, the Informing Science Institute (ISI) is a global community of academics shaping the future of informing science.