gebhart/patrepeval huggingface dataset:
Effect of Lithium Chloride on the "Living" Polymerization of tert-Butyl Methacrylate and Polymer Microstructure Using Monofunctional Initiators (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of Lithium Chloride on the "Living" Polymerization of tert-Butyl Methacrylate and Polymer Microstructure Using Monofunctional InitiatorsSunil K. Varshney, Zhisheng Gao, Xing Fu Zhong, and Adi EisenbergCite this: Macromolecules 1994, 27, 5, 1076–1082Publication Date (Print):February 1, 1994Publication History Published online1 May 2002Published inissue 1 February 1994https://pubs.acs.org/doi/10.1021/ma00083a002https://doi.org/10.1021/ma00083a002research-articleACS PublicationsRequest reuse permissionsArticle Views453Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens. (1995)

Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (GDI3) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. Recently, two isoforms of Rab GDI cDNA were isolated from rats and mice. In this study, we have isolated a brain-type isoform of human Rab GDI cDNA and examined its expression in neuroblastoma. We tentatively designate it as human Rab GDI alpha (hu GDI alpha) and another human Rab GDI, as human Rab GDI beta (hu GDI beta). Hu GDI alpha cDNA encodes a protein of 447 amino acids with a deduced molecular weight of 50,200. Northern blot analysis revealed that hu GDI alpha gene is expressed abundantly in the brain but much less in other tissues, while hu GDI beta gene is ubiquitously expressed. All human neuroblastoma cell lines and tumor specimens examined express hu GDI alpha gene to various extents, while a human T cell leukemia cell line, MOLT3, does not. The levels of both hu GDI alpha and beta mRNA were constant in a human neuroblastoma cell line, NB1, during its neuronal differentiation, while Rab3A and neurofilament-L gene expression and the number of neurosecretory granules were elevated at this condition. These results suggest that hu GDI alpha gene expression is not related to the differentiation state of neuronal cells.
Effect of Tannation of Human LH (1965)

The assay characteristics of and the effect of tannation on human pituitary luteinizing hormone (LH) were determined. The potency of human LH was 13 times that of the ovine LH standard, NIH-LH-S1, when determined in the ventral prostate weight (VPW) assay and 1.5 times NIH-LH-S1 when determined in the ovarian ascorbic acid depletion (OAAD) assay. The potency of human LH was increased 3.2-fold by tannation when measured in the VPW assay and decreased by half when measured in the OAAD assay. The value for the index of discrimination (VPW/OAAD) of the tannated LH was, therefore, 6.4. Confirmatory data were obtained by performing time studies after single injections of tannated or of untannated human LH; the duration of response of the ventral prostate was increased and the duration of the ascorbic acid depletion was decreased after injection of tannated human LH as compared with untannated LH.(Endocrinology77: 588,1965)
Subjective Visual Horizontal During Follow-up After Unilateral Vestibular Deafferentation with Gentamicin (1998)

The subjective visual horizontal (SVH) was measured by means of a small, rotatable, luminous line in darkness in the upright head and body position and at 10, 20 and 30 degrees of tilt to the right and left before, and repeatedly during a follow-up period of 1 year after intratympanic gentamicin instillations in 12 patients with recurrent vertigo attacks. This treatment caused a loss of the bithermal caloric responses on the diseased side. Shortly after treatment there was a significant tilt of SVH towards the treated side (group mean = 10.6 degrees). Repeated testing made it possible to characterize mathematically the changes with time for SVH. For the group of patients as a whole this otolithic component of vestibular compensation was best described by a power function, SVH = 8.65t(-0.16) degrees, where t is time in days after maximum tilt of SVH. After 1 year, SVH was still significantly tilted towards the treated side (group mean = 3.16 degrees). Gentamicin treatment also caused a significant reduction in the perception of head and body tilt towards the deafferented side, while the perception of tilt towards the healthy side did not show any significant changes. During follow-up there was a gradual improvement in the perception of tilt towards the treated side. However, a significant asymmetry in roll-tilt perception was still present 1 year after deafferentation. There was no correlation between SVH in the upright position and roll-tilt perception, suggesting that these parameters are to some extent dependent on different afferent input from the vestibular organ. They were also found to be complementary for the detection of vestibular disturbance.
Integrated planning, scheduling, and dynamic optimization for continuous processes (2014)

Integration of planning, scheduling, and dynamic optimization significantly improves the overall performance of a production process, compared to the traditional sequential method that solves each sub-problem one by one. The integrated model can be formulated as a mixed-integer dynamic optimization (MIDO) problem which can be then transformed into a mixed-integer nonlinear program (MINLP). However, widely-used simultaneous methods, which solve the integrated problem by a general-purpose MINLP solver, encounter computational complexity. They are difficult to apply to large-scale problems. To address this difficulty, we propose a novel efficient method to solve the integrated problem for a multi-product reactor. The method decomposes the dynamic optimization problems from the planning and scheduling problem by discretizing transition times and transition costs. Then the integrated problem is transformed into a mixed-integer linear program, which is much easier to solve than the large-scale MINLP. In the case studies, the proposed method can reduce the computational time by more than three orders of magnitudes in comparison with the simultaneous method.
Intelligent Reasoning for Gas Turbine Fault Isolation and Ambiguity Resolution (2018)

An engine health management (EHM) system typically consists of automated logic for data acquisition, parameter calculation, anomaly detection and eventually, fault identification (or isolation). Accurate fault isolation is pivotal to timely and cost-effective maintenance but is often challenging due to limited fault symptom observability and the intricacy of reasoning with heterogeneous parameters. Traditional fault isolation methods often utilize a single fault isolator (SFI) that primarily relies on gas path performance parameters. While effective for many performance-related faults, such approaches often suffer from ambiguity when two or more faults have signatures that are very similar when monitored by a rather limited number of gas path sensors. In these cases, the ambiguity often has to be resolved by experienced analysts using additional information that takes many different forms, such as various nongas path symptoms, full authority digital engine control fault codes, comparisons with the companion engine, maintenance records, and quite often, the analyst's gas turbine domain knowledge. This paper introduces an intelligent reasoner that combines the strength of an optimal, physics-based SFI and a fuzzy expert system that mimics the analytical process of human experts for ambiguity resolution. A prototype diagnostic reasoner software has been developed and evaluated using existing flight data. Significant performance improvements were observed as compared with traditional SFI results. As a generic reasoning framework, this approach can be applied not only to traditional snapshot data, but to full flight data analytics as well.
Cloning and Sequencing of the Genes Encoding Cyclic Tetrasaccharide-synthesizing Enzymes from<i>Bacillus globisporus</i>C11 (2002)

The genes for isomaltosyltransferase (CtsY) and 6-glucosyltransferase (CtsZ), involved in synthesis of a cyclic tetrasaccharide from alpha-glucan, have been cloned from the genome of Bacillus globisporus C11. The amino-acid sequence deduced from the ctsY gene is composed of 1093 residues having a signal sequence of 29 residues in its N-terminus. The ctsZ gene encodes a protein consisting of 1284 residues with a signal sequence of 35 residues. Both of the gene products show similarities to alpha-glucosidases belonging to glycoside hydrolase family 31 and conserve two aspartic acids corresponding to the putative catalytic residues of these enzymes. The two genes are linked together, forming ctsYZ. The DNA sequence of 16,515 bp analyzed in this study contains four open reading frames (ORFs) upstream of ctsYZ and one ORF downstream. The first six ORFs, including ctsYZ, form a gene cluster, ctsUVWXYZ. The amino-acid sequences deduced from ctsUV are similar in to a sequence permease and a sugar-binding protein for the sugar transport system from Thermococcus sp. B1001. The third ctsW encodes a protein similar to CtsY, suggested to be another isomaltosyltransferase preferring panose to high-molecular-mass substrates.
Macromol. Chem. Phys. 4/2016 (2016)

Front Cover: Tunable and selective areal polymer chain alignment method is developed for conducting polymer blend films of poly(3-hexylthiophene)(P3HT):[6,6]-phenyl-C61-butyric methyl ester (PCBM) system via direct femtosecond laser writing. Interestingly, the P3HT polymer become highly ordered with face-on configuration along the polarization direction of the laser. Further details can be found in the article by S. Chae, K. H. Jo, S. W. Lee, H.-S. Keum, H. J. Kim,* J. Choi,* H. H. Lee* on page 537.
Decentralized Prioritization-Based Management Systems for Distributed Computing (2013)

Fairshare scheduling is an established technique to provide user-level differentiation in management of capacity consumption in high-performance and grid computing scheduler systems. In this paper we extend on a state-of-the-art approach to decentralized grid fairs hare and propose a generalized model for construction of decentralized prioritization-based management systems. The approach is based on (re)formulation of control problems as prioritization problems, and a proposed framework for computationally efficient decentralized priority calculation. The model is presented along with a discussion of application of decentralized management systems in distributed computing environments that outlines selected use cases and illustrates key trade-off behaviors of the proposed model.
Stratway: A Modular Approach to Strategic Conflict Resolution (2011)

In this paper we introduce Stratway, a modular approach to finding long-term strategic resolutions to conflicts between aircraft. The modular approach provides both advantages and disadvantages. Our primary concern is to investigate the implications on the verification of safety-critical properties of a strategic resolution algorithm. By partitioning the problem into verifiable modules much stronger verification claims can be established. Since strategic resolution involves searching for solutions over an enormous state space, Stratway, like most similar algorithms, searches these spaces by applying heuristics, which present especially difficult verification challenges. An advantage of a modular approach is that it makes a clear distinction between the resolution function and the trajectory generation function. This allows the resolution computation to be independent of any particular vehicle. The Stratway algorithm was developed in both Java and C++ and is available through a open source license. Additionally there is a visualization application that is helpful when analyzing and quickly creating conflict scenarios.
THE TREATMENT OF UTERINE FIBROIDS BY X RAYS (1919)

TREATMENT -F UY t 14Ef FIIOIDS BY X' RAYS- Local bulging was present in nine aes) and--when present was a valuable-qign.Whenz the bulging is lateral it is seen best by arranging the patient strsaht in his bed in a good light, and observing from the foot of the bed.In a few cases the bulging was forwards.Epigastric varicosity was not present in any case.Lung complications were present in 13 cases.In 12 they were confined to the right -base and afforaed a dia- gnostic sign of value.The signs observed were: Basal crepitations in 7 cases; basal pneumonia in 4 cases; pleuritic friction sound in 3 cases.In one case from which 5 oz. of pus had been withdrawn, an abscess (probably a second one) burst into the base of the right lung five days later.Ten ounces of brownish pus were coughed up in twenty-four hours, the expectoration became bile-stained on the third day, gradually diminished, and the patient made a good recovery.Decubitus.-Nocharacteristic position was observed.Leucocytosis.-Infourteen of these cases a white blood count was made, and a polymorphonuclear leucocytosis was found in every case.The average white count was 18,600.Rigidity of the right rectus abdominis was observed in about half the cases.From the above analysis it will be seen that there were seven outstanding diagnostic signs present in this series:
Polarized Alignment and Surface Immobilization of Microtubules for Kinesin-Powered Nanodevices (2001)

Kinesin is a nanometer-scale, ATP-powered molecular motor protein that steps along the surface of microtubules. The microtubule tracks are cytoskeletal filaments, 24 nm in diameter, with an overall structural polarity that results from their asymmetric tubulin subunits. Kinesin recognizes the structural polarity and moves toward only one end of a microtubule. A major obstacle in the way of creating kinesin-powered devices is the development of methods for the controlled positioning and alignment of the microtubule tracks. Only by positioning microtubules with defined polarity can kinesin transport, or force generation, be directed efficiently within a device. Here, we report a method to surface immobilize microtubules with approximately 90% parallel alignment using a single-chain antibody that binds α-tubulin exposed at the microtubule minus end.
Lack of Acrosome Formation in Hrb-Deficient Mice (2001)

The sperm acrosome is essential for sperm-egg fusion and is often defective in men with nonobstructive infertility. Here we report that male mice with a null mutation in Hrb are infertile and display round-headed spermatozoa that lack an acrosome. In wild-type spermatids, Hrb is associated with the cytosolic surface of proacrosomic transport vesicles that fuse to create a single large acrosomic vesicle at step 3 of spermiogenesis. Although proacrosomic vesicles form in spermatids that lack Hrb, the vesicles are unable to fuse, blocking acrosome development at step 2. We conclude that Hrb is required for docking and/or fusion of proacrosomic vesicles during acrosome biogenesis.
Detection of specific glycosaminoglycans and glycan epitopes by in vitro sulfation using recombinant sulfotransferases (2010)

Sulfated glycans play critical roles during the development, differentiation and growth of various organisms. The most well-studied sulfated molecules are sulfated glycosaminoglycans (GAGs). Recent incidents of heparin drug contamination convey the importance of having a convenient and sensitive method for detecting different GAGs. Here, we describe a molecular method to detect GAGs in biological and biomedical samples. Because the sulfation of GAGs is generally not saturated in vivo, it is possible to introduce the radioisotope (35)S in vitro using recombinant sulfotransferases, thereby allowing detection of minute quantities of these molecules. This strategy was also successfully applied in the detection of other glycans. As examples, we detected contaminant GAGs in commercial heparin, heparan sulfate and chondroitin samples. The identities of the contaminant GAGs were further confirmed by lyase digestion. Oversulfated chondroitin sulfate was detectable only following a simple desulfation step. Additionally, in vitro sulfation by sulfotransferases allowed us to map glycan epitopes in biological samples. This was illustrated using mouse embryo and rat organ tissue sections labeled with the following carbohydrate sulfotransferases: CHST3, CHST15, HS3ST1, CHST4 and CHST10.
Structure of Human NMN Adenylyltransferase (2002)

Nicotinamide mononucleotide adenylyltransferase (NMNAT), a member of the nucleotidyltransferase alpha/beta-phosphodiesterases superfamily, catalyzes a universal step (NMN + ATP = NAD + PP(i)) in NAD biosynthesis. Localized within the nucleus, the activity of the human enzyme is greatly altered in tumor cells, rendering it a promising target for cancer chemotherapy. By using a combination of single isomorphous replacement and density modification techniques, the human NMNAT structure was solved by x-ray crystallography to a 2.5-A resolution, revealing a hexamer that is composed of alpha/beta-topology subunits. The active site topology of the enzyme, analyzed through homology modeling and structural comparison with other NMNATs, yielded convincing evidence for a substrate-induced conformational change. We also observed remarkable structural conservation in the ATP-recognition motifs GXXXPX(T/H)XXH and SXTXXR, which we take to be the universal signature for NMNATs. Structural comparison of human and prokaryotic NMNATs may also lead to the rational design of highly selective antimicrobial drugs.
Time-gated infrared Fourier-Domain optical coherence tomography (2008)

By combining incoherent time gating (sum-frequency mixing) with coherent gating (optical coherence tomography), we process light backscattered from a sample in the optical domain to improve imaging contrast by 29 dB.
Association football injuries to the brain. A preliminary report. (1981)

In 1975 the authors sent a questionnaire to all players in the Norwegian First Division League Clubs to record the incidence of head injuries due to heading. The conclusion of the questionnaire is that there seems to be a low percentage of serious head injuries. None of the players had been operated on for epi- or subdural hematoma or other brain damage and only a few have had concussion due to heading. In sixty per cent of the players a full neurological examination and EEG recording was undertaken. The result of these studies will be published in a subsequent article.
Coherent FM-CW millimeter-wave radar systems for radar cross section measurements (1990)

Coherent instrumentation radars have been developed at 35 and 94 GHz for use in radar cross section measurements at angles of incidence ranging from 0 degrees to 60 degrees . The systems are designed to measure the radar cross section of various targets, at like and cross-polarizations, in an effort to better understand their scattering characteristics. Both are dual antenna systems capable of operating in FM-CW (frequency-modulated continuous-wave) mode or as pulse or pulse-compression radars. Samples of the transmitted signal are provided for system calibration. The systems also include a phase-locked loop to linearize the sweep in the FM-CW mode of operation. The use of quadrature mixers provides I and Q channels for phase-coherent measurement of the received signals. All hardware is mounted inside weatherproof, lightweight aluminum boxes with the antennas protruding from one side. Multiconductor cables provide control signals and access to the received signals. General-purpose data acquisition computers collect samples of the received signals that are later processed digitally.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Abnormal activity detection in video sequences using learnt probability densities (2004)

Video surveillance is concerned with identifying abnormal or unusual activity at a scene. In this paper, we develop stochastic models to characterize the normal activities in a scene. Given video sequences of normal activity, probabilistic models are learnt to describe the normal motion in the scene. For any new video sequences, motion trajectories are extracted and evaluated using these learnt probabilistic models to identify if they are abnormal or not. In this paper, we have employed the commonly used prototype based representation to describe the movement of individual objects. The model parameters are estimated in the maximum-likelihood framework.
Using a generalized neural network to identify airway obstructions in anesthetized patients post-operatively based on photoplethysmography (2006)

Photoplethysmography has been recently studied as a non-invasive indicator of circulatory and respiratory function. In this study, photoplethysmographic (PPG) data were recorded from patients under the influence of anesthesia, but not intubated. Both time and frequency domain features were extracted from the PPG and used as inputs to a neural network classifier. This classifier considers inter-subject variability so that it generalizes well to a large population. This classifier provided 86.1% accuracy to classify segments as being times of ‘obstructed’ vs. ‘normal’ airways status.
Iodine Nutrition in the United States. Trends and Public Health Implications: Iodine Excretion Data from National Health and Nutrition Examination Surveys I and III (1971–1974 and 1988–1994) (1998)

Iodine deficiency in a population causes increased prevalence of goiter and, more importantly, may increase the risk for intellectual deficiency in that population. The National Health and Nutrition Examination Surveys [NHANES I (1971-1974) and (NHANES III (1988-1994)] measured urinary iodine (UI) concentrations. UI concentrations are an indicator of the adequacy of iodine intake for a population. The median UI concentrations in iodine-sufficient populations should be greater than 10 microg/dL, and no more than 20% of the population should have UI concentrations less than 5 microg/dL. Median UI concentrations from both NHANES I and NHANES III indicate adequate iodine intake for the overall U.S. population, but the median concentration decreased more than 50% between 1971-1974 (32.0+/-0.6 microg/dL) and 1988-1994 (14.5+/-0.3 microg/dL). Low UI concentrations (<5 microg/dL) were found in 11.7% of the 1988-1994 population, a 4.5-fold increase over the proportion in the 1971-1974 population. The percentage of people excreting low concentrations of iodine (UI, <5 microg/dL) increased in all age groups. In pregnant women, 6.7%, and in women of child-bearing age, 14.9% had UI concentrations below 5 microg/dL. The findings in 1988-1994, although not indicative of iodine deficiency in the overall U.S. population, define a trend that must be monitored.