gebhart/patrepeval huggingface dataset:
Text-Like Segmentation of General Audio for Content-Based Retrieval (2009)

Automatic detection of (semantically) meaningful audio segments, or <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">audio</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">scenes</i> , is an important step in high-level semantic inference from general audio signals, and can benefit various content-based applications involving both audio and multimodal (multimedia) data sets. Motivated by the known limitations of traditional low-level feature-based approaches, we propose in this paper a novel approach to discover audio scenes, based on an analysis of <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">audio</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">elements</i> and <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">key</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">audio</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">elements</i> , which can be seen as equivalents to the words and keywords in a text document, respectively. In the proposed approach, an audio track is seen as a sequence of audio elements, and the presence of an audio scene boundary at a given time stamp is checked based on pair-wise measuring the <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">semantic</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">affinity</i> between different parts of the analyzed audio stream surrounding that time stamp. Our proposed model for semantic affinity exploits the proven concepts from text document analysis, and is introduced here as a function of the distance between the audio parts considered, and the co-occurrence statistics and the importance weights of the audio elements contained therein. Experimental evaluation performed on a representative data set consisting of 5 h of diverse audio data streams indicated that the proposed approach is more effective than the traditional low-level feature-based approaches in solving the posed audio scene segmentation problem.
Imaging the effects of anti-angiogenic treatments. (2003)

It is clear that various imaging modalities have given keen insight into the molecular mechanisms involved in anti-angiogenic treatments. A key to the advancement of anti-angiogenic therapy is not only the discovery of new drugs and treatments, but the analysis of the specific modes of action of these compounds in order to produce the next generation with greater effectiveness. While existing clinical methods incorporate the analysis of serum and urine to measure angiogenic factors, an imaging technique monitoring the effectiveness of anti-angiogenic therapy would be a convenient, noninvasive, cost effective technique to aid in treatment planning and disease management.
Chondrogenic phenotype of different cells encapsulated in κ‐carrageenan hydrogels for cartilage regeneration strategies (2012)

Engineering articular cartilage substitutes using hydrogels with encapsulated cells is an approach that has received increasing attention in recent years. Hydrogels based on κ-carrageenan (κC), a thermoreversible natural-origin polymer, have been recently proposed as new cell/growth factor delivery vehicles for regenerative medicine. In this work, we report the potential of such hydrogels encapsulating either human-adipose-derived stem cells (hASCs), human nasal chondrocytes (hNCs), or a chondrocytic cell line (ATDC5) for cartilage regeneration strategies. The in vitro cellular behavior of the encapsulated cells within κC hydrogel was analyzed after different culturing periods using biochemical assays and histological and real-time reverse-transcription PCR analysis. The three types of cells encapsulated in κC hydrogels showed good cellular viability and proliferation up to 21 days of culture, and the cell-laden hydrogels were positive for specific cartilage markers. In summary, the results demonstrate that hASCs embedded in κC hydrogels proliferate faster and exhibit higher expression levels of typical cartilage markers as compared with hNCs or ATDC5 cells. Based on these data, it is possible to conclude that κC hydrogel provides a good support for culture and differentiation of encapsulated cells and that hASCs may provide an advantageous alternative to primary chondrocytes, currently used in clinical treatments of cartilage defects/diseases.
An interference robust CDMA demodulator that uses spectral correlation properties (2002)

A technique is presented for effectively rejecting CDMA interference. No knowledge of the interfering signals is required. The demodulator uses a cyclic Wiener filter (FRESH filter) to decrease the bit error rate, and increase spectral efficiency. In some situations, the bit error rate is reduced by more than two orders of magnitude and capacity is tripled. For despreading and demodulating the signal-of-interest, the demodulator takes on a structure similar to that of fractionally-spaced equalizers. Substantial improvement over the conventional correlation receiver is obtained by exploiting spectral correlation of the signal-of-interest and the multiple access interference even with severe multipath distortion. The computational complexity of the receiver is equivalent to that of conventional equalizers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Retinoid Signaling System — A Target in Dioxin Toxicity (2002)

This review summarizes the available data on the effects of dioxins on retinoid levels, retinoid-related enzyme activities, and toxicological endpoints that have been correlated to retinoid effects. Similarities between dioxin toxicity and retinoid deficiency as well as retinoid excess are pointed out. Several possible levels of interaction between the dioxin and the retinoid signaling pathways are discussed, including the involvement of the Ah receptor, altered retinoic acid homeostasis, and an altered set point for retinoid storage. A hypothesis for the effect of dioxins on retinoids is suggested. In this hypothesis, comprising two cascades of effects on the molecular level, the effect of dioxins on retinoic acid levels is central.
Renal Cell Carcinoma (1988)

No AccessJournal of UrologyEditorial1 Feb 1988Renal Cell Carcinoma W. Marston Linehan W. Marston LinehanW. Marston Linehan More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)42405-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Renal Cell Carcinoma." The Journal of Urology, 139(2), pp. 340–341 © 1988 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited bySingh M, Kralovec J, Mezei M and Ghose T (2018) Inhibition of Human Renal Cancer by Methotrexate Linked to a Monoclonal AntibodyJournal of Urology, VOL. 141, NO. 2, (428-431), Online publication date: 1-Feb-1989. Volume 139Issue 2February 1988Page: 340-341 Advertisement Copyright & Permissions© 1988 by The American Urological Association Education and Research, Inc.MetricsAuthor Information W. Marston Linehan More articles by this author Expand All Advertisement PDF downloadLoading ...
Curcumin Reduces Burn Progression in Rats (2007)

Pretreatment of rats with oral curcumin followed by once-daily oral treatment for three days reduced the percentage of unburned skin interspaces that progressed to full necrosis.
An adaptive radius adjusting method for RBF networks considering data densities and its application to plant control technology (2009)

We previously proposed a control technology to reduce CO and NOx emissions in power generating. In this technology, an optimal control logic is obtained by Reinforcement Learning (RL) and a Radial Basis Function (RBF) network which constructs a response surface for the CO and NOx properties. An improvement of estimation accuracy of the response surface can enhance the control logic performance, so the radius of RBF network should be determined properly since it is one of the most influential factors on estimation accuracy. On the other hand, adjustment of the radius should be executed within several minutes as computational time for constructing the response surface is restricted. In this paper, we propose a new radius adjusting method for RBF networks to achieve high estimation accuracy and short computational time. This method adjusts radii based on the densities of learning data, thus it can achieve both high estimation accuracy and short computational time. The results of our evaluation showed that the proposed method had higher estimation accuracy than conventional methods within a practical computational time.
An Automated Microprocessor-Controlled Rb-82 Generator for Positron Emission Tomography Studies (1984)

Radioisotope generators provide a desirable alternative to cyclotrons for the production of short lived positron emitters. A fully automated microprocessor controlled generator system for obtaining 76 sec rubidium-82 is described in detail. Column adsorbants, specifications and eluent solutions are discussed in determining generator performance for yield, breakthrough, and stability for long term use. Some examples of clinical applications in positron emission tomography are presented.
Planar InP/InGaAs avalanche photodiodes with preferential lateral extended guard ring (1986)

High-speed and high-sensitivity planar InP/InGaAs avalanche photodiodes (APD's) have been fabricated with a newly developed preferential lateral extended guard ring (PLEG). By employing the configuration, avalanche photodiode yield was markedly improved without edge breakdown. Received powers required to give 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-9</sup> bit-error rate (BER) at 1.55-1.57-µm wavelength were -44.5 and -37.4 dBm for 450 Mbit/s and 2 Gbit/s, respectively.
Llanto por el tigre (2011)

I introduce arguments toward a non-representational reflexivity theory of consciousness-as-such to address one of the key issues in the science of consciousness today: lack of understanding of the nature of consciousness itself. An expanded map of consciousness is outlined, which includes, in addition to the well-known contents of awareness and levels of arousal, the indeterminate substrate and consciousness-as-such or nondual awareness. The central idea presented is that consciousness-as-such is a non-conceptual nondual awareness, whose essential property is non-representational reflexivity. This property makes consciousness-as-such phenomenologically, cognitively and neurobiologically a unique kind, different from and irreducible to any contents, functions and states, including the indeterminate substrate. Our previous hypothesis on the precuneus network for nondual awareness is further discussed in relation to non-representational reflexivity, and in the light of other hypotheses on the neural correlates of consciousness-as-such.
Mapping and re-localization for mobile augmented reality (2014)

Using Simultaneous Localization And Mapping (SLAM) methods become more and more common in Augmented Reality (AR). To achieve real-time requirement and to cope with scale factor and the lack of absolute positioning issue, we propose to decouple the localization and the mapping step. We explain the benefits of this approach and how a SLAM strategy can still be used in a way that is meaningful for the end user. The method we proposed has been fully implemented on various smartphone in order to show its efficiency.
Angiotensins II and IV stimulate the rat adrenocortical cell proliferation acting via different receptors. (2001)

Both Ang II and Ang IV stimulate the adrenocortical cell proliferation in the rat, but they act via different receptors - AT1 in the case of Ang II and non-AT1 (probably AT4) in the case of Ang IV.
Coherence-aware stereophonic residual echo estimation (2017)

The performance of stereophonic acoustic echo cancelers is highly dependent on the coherence between the loudspeaker signals. If this is high, convergence is slow, during which audible residual echoes remain. Residual echoes can be reduced by applying a residual echo suppressor to the canceler’s output. Yet, in order to obtain the post- filter gains, it is necessary to estimate the residual echoes first, and the performance of stereophonic residual echo estimators also de- pends on the loudspeaker signals coherence. In this paper, a stereo- phonic residual echo estimator is proposed that takes the coherence between the signals into account. By doing this, it is possible to reliably estimate the residual echoes, even if the loudspeaker signals are completely coherent.
3D object modeling using spatial and pictographic gestures (1998)

Article 3D object modeling using spatial and pictographic gestures Share on Authors: Hiroaki Nishino Dept. of Computer Science and Intelligent Systems, Oita University, Oita 870-1192, JAPAN Dept. of Computer Science and Intelligent Systems, Oita University, Oita 870-1192, JAPANView Profile , Kouichi Utsumiya Dept. of Computer Science and Intelligent Systems, Oita University, Oita 870-1192, JAPAN Dept. of Computer Science and Intelligent Systems, Oita University, Oita 870-1192, JAPANView Profile , Kazuyoshi Korida Dept. of Communication, Oita Pref. College of Arts and Culture, Oita 870-0833, JAPAN Dept. of Communication, Oita Pref. College of Arts and Culture, Oita 870-0833, JAPANView Profile Authors Info & Claims VRST '98: Proceedings of the ACM symposium on Virtual reality software and technologyNovember 1998 Pages 51–58https://doi.org/10.1145/293701.293708Online:02 November 1998Publication History 22citation971DownloadsMetricsTotal Citations22Total Downloads971Last 12 Months11Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Production of Term Offspring by In Vitro Fertilization Using Old Mouse Spermatozoa. (1995)

We successfully produced offspring of old male BDF1 mice using in vitro fertilization. Although 7 old male mice (33 months of age) were infertile and revealed frequent degeneration in the seminiferous epithelia, 4 of them had spermatozoa in the caudae epididymides. The IVF rate of their sperm with eggs from young ICR mice was very high (82.0%). The production rate of offspring was also satisfactory (61.6%). The present study indicates that the IVF method is useful for producing offspring of aged male mice.
Grouping and parameterizing irregularly spaced points for curve fitting (2000)

Given a large set of irregularly spaced points in the plane, an algorithm for partitioning the points into subsets and fitting a parametric curve to each subset is described. The points could be measurements from a physical phenomenon, and the objective in this process could be to find patterns among the points and describe the phenomenon analytically. The points could be measurements from a geometric model, and the objective could be to reconstruct the model by a combination of parametric curves. The algorithm proposed here can be used in various applications, especially where given points are dense and noisy. Examples demonstrating the behavior of the algorithm under noise and density of the points are presented and discussed.
Mouse hematopoietic stem cells and the interaction of<i>c‐kir</i>receptor and steel factor (1991)

Hematopoietic stem cells (HSCs) are distinguished from other hematopoietic progenitors in bone marrow by their unique ability to undergo multilineage differentiation and self-renewal. Two mouse mutations, dominant spotting (W) and steel (Sl), have pleiotropic effects on hematopoiesis, gametogenesis, and melanoblast development. These two mutations have been shown to be intrinsic (W) and microenvironmental (Sl) defects. Recently, molecular studies revealed that the W and Sl loci encode the c-kit receptor and steel factor (SLF), respectively. The c-kit receptor is expressed on HSCs and hematopoietic progenitors, while SLF is produced by stromal cells. SLF acts on hematopoietic progenitors synergistically with other growth factors. Here we review the effect of these mutations on mouse hematopoiesis, and show that SLF acts on HSCs and other myeloerythroid progenitors, but that it, in our hands, does not play a critical role in HSC generation or self-renewal. Rather, SLF is the most potent co-mitogen (with IL-1, IL-3, IL-6, G-CSF, GM-CSF, or M-CSF) found that acts on these cells, but the effect of such treatments is the rather specific and massive expansion of myeloerythropoiesis, not lymphopoiesis, and perhaps at the expense of HSC self-renewal.
Serum albumin as a local therapeutic agent in cell therapy and tissue engineering (2016)

Albumin is a major plasma protein that has become ubiquitous in regenerative medicine research. As such, many studies have examined its structure and advantageous properties. However, a systematic and comprehensive understanding of albumin's role, capabilities and therapeutic potential still eludes the field. In the present work, we review how albumin is applied in tissue engineering, including cell culture and storage, in vitro fertilization and transplantation. Furthermore, we discuss how albumin's physiological role extends beyond a carrier for metal ions, fatty acids, pharmacons and growth factors. Albumin acts as a bacteriostatic coating that simultaneously promotes attachment and proliferation of eukaryotic cells. These properties with the combination of free radical scavenging, neutrophil activation and as a buffer molecule already make the albumin protein beneficial in healing processes supporting functional tissue remodeling. Nevertheless, recent data revealed that albumin can be synthesized by osteoblasts and its local concentration is raised after bone trauma. Interestingly, by increasing the local albumin concentration in vivo, faster bone healing is achieved, possibly because albumin recruits endogenous stem cells and promotes the growth of new bone. These data also suggest an active role of albumin, even though a specific receptor has not yet been identified. Together, this discussion sheds light on why the extravascular use of the albumin molecule is in the scope of scientific investigations and why it should be considered as a local therapeutic agent in regenerative medicine. © 2016 BioFactors, 43(3):315-330, 2017.
Boost Up Mobility of Solution‐Processed Metal Oxide Thin‐Film Transistors via Confining Structure on Electron Pathways (2014)

Novel structure-engineered amorphous oxide semiconductor thin-film transistors using a solution process to overcome the trade-off between high mobility and other parameters (i.e., on/off ratio, sub-threshold voltage swing, threshold voltage, and so on) are proposed. High performance confining structure-engineered AOS TFTs are successfully demonstrated, which utilize a specially designed layer with ultra-high density and high electron mobility.
A Novel Method to Evaluate the Community Built Environment Using Photographs – Environmental Profile of a Community Health (EPOCH) Photo Neighbourhood Evaluation Tool (2014)

Analysis of photos using a standardized protocol as described in this study offers a means to obtain reliable and reproducible information on the built environment in communities in very diverse locations around the world. The collection of the photographic data required minimal training and the analysis demonstrated high reliability for the majority of items of interest.
Peptide Dose, MHC Affinity, and Target Self-Antigen Expression Are Critical for Effective Immunotherapy of Nonobese Diabetic Mouse Prediabetes (2000)

Cross-reactive T cells that recognize both Tep69 (dominant nonobese diabetic (NOD) T cell epitope in ICA69 (islet cell autoantigen of 69 kDa)) and ABBOS (dominant NOD T cell epitope in BSA) are routinely generated during human and NOD mouse prediabetes. Here we analyzed how systemic administration of these mimicry peptides affects progressive autoimmunity in adoptively transferred and cyclophosphamide-accelerated NOD mouse diabetes. These models were chosen to approximate mid to late stage prediabetes, the typical status of probands in human intervention trials. Unexpectedly, high dose (100 microg) i.v. ABBOS prevented, while Tep69 exacerbated, disease in both study models. Peptide effects required cognate recognition of endogenous self-Ag, because both treatments were ineffective in ICA69null NOD congenic mice adoptively transferred with wild-type, diabetic splenocytes. The affinity of ABBOS for NOD I-A(g7) was orders of magnitude higher than that of Tep69. This explained 1) the expansion of the mimicry T cell pool following i.v. Tep69, 2) the long-term unresponsiveness of these cells after i.v. ABBOS, and 3) precipitation of the disease after low dose i.v. ABBOS. Disease precipitation and prevention in mid to late stage prediabetes are thus governed by affinity profiles and doses of therapeutic peptides. ABBOS or ABBOS analogues with even higher MHC affinity may be candidates for experimental intervention strategies in human prediabetes, but the dose translation from NOD mice to humans requires caution.
MIKEY-SAKKE: Sakai-Kasahara Key Encryption in Multimedia Internet KEYing (MIKEY) (2012)

This document describes MIKEY-SAKKE, a method of key exchange designed
for use in IP Multimedia Subsystem (IMS) [3GPP.33.328] Media Plane
Security, but with potential for wider applicability. The MIKEY-SAKKE
mode uses Identifier-based Public Key Cryptography (IDPKC) to
establish a shared secret value and certificate-less signatures to
provide source authentication. MIKEY-SAKKE has a number of desirable
features, including simplex transmission, scalability, low-latency
call setup, support for Lawful Interception (LI) and support for
secure deferred delivery.
Biosynthesis of anthracydines: enzymic conversion of aklanonic acid to aklavinone and  -rhodomycinone by anthracycline-producing streptomycetes (1990)

Aklanonic acid, a substituted anthraquinone, is the earliest stable intermediate isolated so far in the biosynthesis of anthracycline antibiotics. Desalted, soluble cell extracts of Streptomyces sp. C5 and Streptomyces peucetius (ATCC 29050) converted aklanonic acid to ε-rhodomycinone in an S-adenosyl-l-methionine- and NADPH-dependent sequence of reactions. Aklanonic acid was methylated to form aklanonic acid methyl ester (AAME), which was cyclized to form aklaviketone. Aklaviketone was reduced to aklavinone by an NADPH-linked reductase. When extracts of Streptomyces sp. C5 and S. peucetius were used, aklavinone was hydroxylated at C-11 by an NADPH- and oxygen-dependent reaction to form ε-rhodomycinone. Cell extracts of Streptomyces galilaeus strains ATCC 31133 and 31671 converted aklanonic acid to aklavinone in the same manner, but neither of the S. galilaeus strains hydroxylated aklavinone to ε-rhodomycinone. Mutants of Streptomyces sp. C5 blocked at steps in the conversion of aklanonic acid to aklavinone, and which accumulated aklanonic acid (SC5-39; dauC), AAME (SC5-138; dauD, dauE), and aklaviketone (SC5–159; dauE, dauF), lacked the expected enzymic activities. In a mutant (SC5–24; dauE) lacking aklaviketone reductase, but retaining aklavinone 11-hydroxylase activity, maggiemycin was formed as an apparent shunt product. An enzymic pathway for ε-rhodomycinone and maggiemycin formation is consistent with the data presented.