gebhart/patrepeval huggingface dataset:
<b>A cell‐free system of Tn<i>3</i> transposition and transposition immunity</b> (1996)

Transposition of Tn3 and transposition immunity could be reproduced in vitro. The results demonstrate that the binding of transposase to domain B of the IR sequence in the target replicon is responsible for transposition immunity. We propose that the transposition immunity results from conversion of the normal synaptic complex formed between the donor and target molecules to another complex which is inactive for transposition, due to the interaction between transposases binding to the IR sequences in the donor and target molecules.
Experimental and Numerical Studies of Droplet and Particle Formation in Electrohydrodynamic Atomization (2008)

Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, NSTI-Nanotech, Nanotechnology 2008
Loss of heterozygosity in familial tumors from three BRCA1-linked kindreds. (1994)

BRCA1, a breast-ovarian cancer susceptibility gene which has been localized to 17q21, appears to be a tumor suppressor gene based on evidence from loss of heterozygosity (LOH) studies. We analyzed 14 ovarian and breast tumors from BRCA1 carriers and 1 sporadic breast tumor from 3 kindreds for 17q21 LOH. Thirteen of the 14 tumors from gene carriers exhibited LOH of the wild-type allele. Tumors from one gene carrier and the sporadic breast case did not exhibit any LOH in the region. There was loss of the wild-type allele from both maternally and paternally derived chromosomes, therefore excluding the possibility of genomic imprinting and providing further evidence that BRCA1 is a tumor suppressor. Three tumors showed interstitial LOH in the region, and thus established the utility of familial tumors in refining a region surrounding a tumor suppressor gene in a manner analogous to using genetic recombinants.
Synthetic Medium for <i>Acetobacter xylinum</i> That Can Be Used for Isolation of Auxotrophic Mutants and Study of Cellulose Biosynthesis (1989)

Acetobacter xylinum is a bacterium that can synthesize cellulose when grown in an undefined medium containing glucose. We developed a defined minimal medium for A. xylinum that contains 1% glucose, 0.1% NH(4)Cl, 0.115% citric acid, 0.33% Na(2)HPO(4), 0.01% KCl, 0.025% MgSO(4). 7H(2)O, and 7.5 mg of nicotinamide per liter which both allows cellulose synthesis and can be used to isolate a variety of auxotrophic mutants.
Local Antibody Response in Peyer’s Patches to the Orally Administered Dietary Protein Antigen (1999)

To understand local antibody production to dietary protein antigens in the gut, the reactivity of the monoclonal antibodies (mAbs) from Peyer's patches of BALB/c mice raised against orally administered hen egg lysozyme (HEL) was studied. These mAbs were of IgG1 (7 clones), IgA (5 clones) and IgM (13 clones) isotypes. Some of the HEL-binding mAbs preferentially reacted with reduced, carboxy-methylated HEL, rather than with native HEL. MAbs of the IgA and IgM isotypes had cross-reactivity with other unrelated environmental antigens such as E. coli, single-strand DNA, and soluble components of mouse food. In contrast, the IgG1 mAbs did not cross-react with these antigens. The average of the Kd values for HEL of these mAbs was in the order of 10(-6) M, which is moderately higher than those of mAbs from the preimmune repertoire. These results suggest that, under normal physiological conditions, orally administered dietary proteins predominantly induce the local production of polyreactive IgA/IgM antibodies cross-reacting with environmental luminal antigens.
Activity of an Iron Oxide–Chromium Oxide Water-Gas Shift Catalyst (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTActivity of an Iron Oxide–Chromium Oxide Water-Gas Shift CatalystKenton Atwood and M. R. ArnoldCite this: Ind. Eng. Chem. 1953, 45, 2, 424–426Publication Date (Print):February 1, 1953Publication History Published online1 May 2002Published inissue 1 February 1953https://pubs.acs.org/doi/10.1021/ie50518a048https://doi.org/10.1021/ie50518a048research-articleACS PublicationsRequest reuse permissionsArticle Views171Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A GNU Radio Based Software-Defined Radar (2007)

The behavioral effects of bilateral N-methyl-D-aspartate (NMDA) lesions of the core and medial shell subregions of the nucleus accumbens were evaluated in rats. Body weight was monitored for 2 weeks following surgery. Locomotor activity and open field behavior were recorded 1 week after surgery. The core-lesion group had difficulty recovering from the lesion and had significantly lower weights throughout the experiment. The shell-lesion group had normal recovery and weighed significantly more than controls over the course of the experiment. In the activity cage test, the core-lesion group was hyperactive when compared to controls and to the shell-lesion group. Activity of the shell-lesion group was similar to that of their sham-controls. Three weeks postlesion, the core-lesion group was still significantly more active. In the open field test, peripheral locomotion scores were significantly higher in the core-lesion group when compared to their controls, whereas the scores of the shell-lesion group were similar to controls. In the other open field measures, both lesion groups were hyperactive; however, the scores of core-lesion group were significantly higher than those of the shell-lesion group on all measures. Histological analysis indicated small, discrete areas of damage within the core or medial shell accumbens regions. These preliminary results suggest that these two subregions can be behaviorally differentiated.
The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2Aβ catalytic subunit (1988)

Journal Article The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2Aβ catalytic subunit Get access Brian A. Hemmings, Brian A. Hemmings Friedrich Miescher-InstitutCH-4002 Basel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Wolfgang Wernet, Wolfgang Wernet Friedrich Miescher-InstitutCH-4002 Basel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Regina Mayer, Regina Mayer Friedrich Miescher-InstitutCH-4002 Basel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Francis Maurer, Francis Maurer Friedrich Miescher-InstitutCH-4002 Basel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Jan Hofsteenge, Jan Hofsteenge Friedrich Miescher-InstitutCH-4002 Basel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Stuart R. Stone Stuart R. Stone Friedrich Miescher-InstitutCH-4002 Basel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 16, Issue 23, 9 December 1988, Page 11366, https://doi.org/10.1093/nar/16.23.11366 Published: 09 December 1988 Article history Accepted: 31 October 1988 Published: 09 December 1988
Studies on the Superoxide Releasing Site in Plasma Membranes of Neutrophils with ESR Spin-Labels (1990)

Superoxide (O2-)-generating membranes of pig blood neutrophils were studied by the ESR spin-label method. Neutrophils were spin-labeled with doxylstearic acids, consisting of nitroxide free radicals bonded to the 5, 7, 12, or 16 position of stearic acid (5-, 7-, 12-, or 16-DS), to detect the reduction of their nitroxide radicals at different positions in the membrane. The spin-labeled cells were then stimulated with phorbol myristate acetate (PMA). Stimulation of the labeled cells resulted in a marked decrease in the spin concentration of 5-DS due to the reduction by O2-, but not in those of the other three DS labels. This reduction of 5-DS was completely inhibited by copper salicylate (CS), a hydrophobic and permeable O2(-)-scavenger, but not by superoxide dismutase (SOD). CS was not inhibitory on the respiratory burst, i.e., O2(-)-generating activity of neutrophils. On the contrary, if the spin-labels were present in the extracellular medium, SOD inhibited the reduction of all four DS labels due to O2- released from PMA-stimulated cells. These results suggest that the O2(-)-releasing site is not located at the outer surface of the plasma membrane but in an inner hydrophobic environment a short distance (around 4-5 A) from its outer surface.
Systolic (VLSI) arrays for relational database operations (1980)

This paper proposes the use of VLSI technology to perform relational database operations directly in hardware. It is shown that relational compulations, such as intersection, remove-duplicates, union, join, and division, can all be pipelined elegantly and efficiently on networks of processors having an array structure. These (systolic) processor arrays are readily and cost-effectively implementable with present technology, due to the extreme simplicity of their processors, and the high regularity of their interconnection structures.
Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes (2013)

Neural precursor cells of the ventricular zone give rise to all neurons and glia of the central nervous system and rely for maintenance of their precursor characteristics on the closely related SoxB1 transcription factors Sox1, Sox2 and Sox3. We show in mouse spinal cord that, whereas SoxB1 proteins are usually downregulated upon neuronal specification, they continue to be expressed in glial precursors. In the oligodendrocyte lineage, Sox2 and Sox3 remain present into the early phases of terminal differentiation. Surprisingly, their deletion does not alter precursor characteristics but interferes with proper differentiation. Although a direct influence on myelin gene expression may be part of their function, we provide evidence for another mode of action. SoxB1 proteins promote oligodendrocyte differentiation in part by negatively controlling miR145 and thereby preventing this microRNA from inhibiting several pro-differentiation factors. This study presents one of the few cases in which SoxB1 proteins, including the stem cell factor Sox2, are associated with differentiation rather than precursor functions.
The penetration of ultra‐violet light into pure water and sea‐water (1928)

Measurements were made in the ultra‐violet spectrum region λ4000 to 2500 Å of the light‐absorption coefficients of pure water and sea‐water and of the molecular absorption‐coefficients of aqueous solutions of the principal salts in the sea. There is a close correspondence between the falling off in the transparency of the sea with decreasing wave‐length in the ultra‐violet and the spectral energy‐curve of sunlight. This, together with the very similar correspondence in the case of the transparency of the atmosphere permits the suggestion that the actinic effects of sunlight may have played a part, perhaps more important than has been heretofore recognized, in the constitution of the sea and the air.
Recent Advances in the Development of Materials for Terahertz Metamaterial Sensing (2021)

Abstract Terahertz metamaterial sensing (TMS) is a new interdisciplinary technology. A TMS system employs terahertz waves as the pumping source, these then interact with the sample and carry the substance information, e.g., refractive index, absorption spectra. These properties are relevant to the molecular rotation and vibration states produced by a surface‐plasmon‐polariton‐like effect. TMS technology is usually characterized by large penetration depth and high sensitivity. Owing to these advantages, TMS may be used for ultratrace detection and consequently has a wide range of practical applications in biomedicine, food safety, environmental monitoring, industry and agriculture, material characterization, and safety inspection. Furthermore, TMS performance is determined not only by the structural topology of metamaterials, but also by their compositions and substrates. This paper reviews the essential fundamentals, relevant applications, and recent advances in TMS technology with a focus on the influence of material selection on TMS performance. This review is envisaged to be used as a key reference for developing TMS‐based functional devices with enhanced characteristics.
[The current feature of the study on human coagulation factor IX mutant]. (2005)

Hemophilia B is an X-linked bleeding disease, caused by the mutations of human coagulation factor IX (hFIX) gene located in chromosome X. It results in a dramatic decline of hFIX quantity or clotting activity in plasma, and the intrinsic clotting pathway is affected seriously. In this article, the structure and function of hFIX gene as well as the protein encoded by this gene were reviewed. Various types of hFIX mutants found in hemophilia B were also described, including the mutations caused by founder effects, mutations in regulatory region, coding region, splicing sites of introns and two other special mutations. Meanwhile, the biological effects of the mutations described above were discussed. Finally, a mutation type (Arg-->Ala at point 338) that can increase the clotting activity of hFIX as well as the potential application was briefly introduced.
Relationships between B cell and myeloid differentiation. Studies with a B lymphocyte progenitor line, HAFTL-1. (1988)

A cell line, HAFTL-1, derived by in vitro transformation of fetal liver cells with v-Ha-ras, was found to have molecular and phenotypic characteristics of pro-B cells recently committed to the Ly-1+ B cell differentiation pathway. Stimulation of these cells with LPS resulted in their differentiation within either the B or myelomonocytic lineages. Thus, lines derived from LPS-stimulated HAFTL-1 cells were shown to be clonally related, as evidenced by common v-ras integrations, but to exhibit characteristics of pre-B cells (ThB expression, continuing DJ heavy chain rearrangements) or mature macrophages (expression of Mac-1 and Mac-2, lysozyme and nonspecific esterase production, phagocytosis) while maintaining their Ly-1+ phenotype. These results suggest that events resulting in the irrevocable commitment to a single lineage occur late in differentiation, at least within the pathway yielding Ly-1+ B cells and a proposed subpopulation of Ly-1+ monocytes and macrophages. Final commitment to these lineages is carefully orchestrated, as evidenced by restricted expression of Ly-5 isoforms and production of IgH transcripts.
Film Self-Assembly of Oppositely Charged Macromolecules Triggered by Electrochemistry through a Morphogenic Approach (2015)

The development of new surface functionalization methods that are easy to use, versatile, and allow local deposition represents a real scientific challenge. Overcoming this challenge, we present here a one-pot process that consists in self-assembling, by electrochemistry on an electrode, films made of oppositely charged macromolecules. This method relies on a charge-shifting polyanion, dimethylmaleic-modified poly(allylamine) (PAHd), that undergoes hydrolysis at acidic pH, leading to an overall switching of its charge. When a mixture of the two polyanions, PAHd and poly(styrenesulfonate) (PSS), is placed in contact with an electrode, where the pH is decreased locally by electrochemistry, the transformation of PAHd into a polycation (PAH) leads to the continuous self-assembly of a nanometric PAH/PSS film by electrostatic interactions. The pH decrease is obtained by the electrochemical oxidation of hydroquinone, which produces protons locally over nanometric distances. Using a negatively charged enzyme, alkaline phosphatase (AP), instead of PSS, this one-pot process allows the creation of enzymatically active films. Under mild conditions, self-assembled PAH/AP films have an enzymatic activity which is adjustable simply by controlling the self-assembly time. The selective functionalization of microelectrode arrays by PAH/AP was achieved, opening the route toward miniaturized biosensors.
Something for nothing: exploring the importance of strong reciprocity in the Greater Caribbean (2010)

espanolCuando se habla sobre intercambio en el registro arqueologico, esto implica a menudo la asuncion de una prehistoria centrada en los aspectos economicos o politicos de los intercambios. Estos puntos de vista, frecuentemente suponen una disposicion directa quidpro- quo, a los intercambios. Aunque la reciprocidad directa fue, sin dudas, importante para la constitucion de la sociabilidad pre-colombina, hay muchas otras estrategias sociales que tuvieron al menos, tanta importancia como esta. El presente articulo se centra en el posible papel jugado por una �reciprocidad fuerte�, en las interacciones pan-caribenas. Esto implica que objetos y conceptos no deben ser solo considerados por su valor como bienes de cambio, en un sentido economico o ideologico sino tambien por su habilidad de crear manifestaciones materiales de estrategias sociales y de sus relaciones resultantes. Esta posicion sera ilustrada por casos de estudio tomados de la Etnografia de Melanesia y de la Arqueologia del Caribe. EnglishWhen discussing exchange in the archaeological record, this often entails a prehistory of exchange that is focused on the economic or the political aspect of exchanges. These particular views very often suppose a direct quid-pro-quo attitude to exchanges. Although direct reciprocity was no doubt important for the constitution of pre-Columbian sociality, many other social strategies are available that were at least as important. This article focuses on the possible role of strong reciprocity in pan-Caribbean interactions. This entails that objects and concepts should not be only considered for their value as exchange valuables in an economic or ideological sense, but also from their ability to create material manifestations of social strategies and their resulting relations. This position will be illuminated by a casestudy taken from Melanesian ethnography and Caribbean archaeology. francaisLorsque l�on traite des echanges dans les travaux archeologiques, il est generalement fait reference a une prehistoire des echanges centree sur les seuls aspects economiques ou politiques. Ce point de vue implique tres souvent une attitude de contrepartie directe dans les echanges. Bien que la reciprocite directe occupât sans doute une place importante dans la constitution de la sociabilite precolombienne, beaucoup d�autres strategies sociales, au moins aussi importantes, etaient envisageables. Cet article se concentre sur le possible role de la reciprocite stricte dans les interactions pan-caribeenne. Cela implique que les objets et les concepts ne doivent pas etre seulement consideres pour leur valeur comme objets precieux d�echange, au sens economique ou ideologique, mais doivent l�etre aussi pour leur capacite a creer des manifestations materielles des strategies sociales et des relations resultantes. Cette reflexion sera illustree d�une etude de cas tires de l�ethnographie melanesienne et de l�archeologie caribeenne.
Risk-Sensitive Markov Decision Processes (1972)

This paper considers the maximization of certain equivalent reward generated by a Markov decision process with constant risk sensitivity. First, value iteration is used to optimize possibly time-varying processes of finite duration. Then a policy iteration procedure is developed to find the stationary policy with highest certain equivalent gain for the infinite duration case. A simple example demonstrates both procedures.
Emerging separation technologies for metals and fuels (1993)

This conference was held during March 13-18, 1993 at Palm Coast, Florida. The purpose of this conference was to provide a forum for exchange of information on separation technologies for metals and fuels. Topic of discussion include: inorganic and environmental separation technologies; reagent synthesis; environmental regulations and consequences; interfacial phenomenon/processes; biotechnology separations; flowsheet development; membranes; thermal processes; environmental processes; and value added products and fuel separations. Individual papers have been processed for inclusion in the appropriate data bases.
Polymers from Renewable Resources. X. Semi-Interpenetrating Polymer Networks Based on Castor Oil Polyurethane and Cardanol-Furfural Resin: Scanning Electron Microscopy and XRD Studies (1995)

Abstract A number of semi-interpenetrating polymer networks (Semi-IPNs) were synthesized by reacting the polyurethane prepared from castor oil and diisocyanates and the resin prepared from cardanol and furfural. The physico-chemical properties of the semi-IPNs have been investigated. The scanning electron microscopy of some of the semi-IPNs have been studied and the morphology has been examined. The samples were subjected to wide angle X-ray diffraction analysis. The degree of crystallinity (Xcr) were computed on the basis of crystal defect concept developed by Roland and Vonk.
Geometric Evaluation of Mandibular Distraction (1995)

In planning mandibular distraction, the deficiency of the vertical ramus and body is measured. The position of the pin placement is evaluated by the following formula: [formula: see text] This is more accurately presented by the new formula. [formula: see text] In one patient the original formula evaluated the pin placement angle to be 9.94, compared with 9.92, in the more accurate but more complex new formula. When the gonial angle is obtuse, the difference is small. When the gonial angle is more acute, as in a normal gonial angle for a 2-year-old child--134 degrees--the difference is still only 0.1 degree. The original formula is simpler to use and is accurate enough for clinical use in mandibular distraction. The distraction distance is not the sum of the vertical ramal deficiency plus the body deficiency but is given by the following formula: [formula: see text] It would be accurate enough to plan the total distraction distance to be less than the sum of the two distances. The more acute the gonial angle is, the less the distraction distance will need to be.
Structural and electrical characterization of PZT and PLZT films grown on spin-on processed conductive oxide electrodes (1995)

Abstract A spin-on processing technique has been developed to grow conductive oxide electrodes e.g. RuOx as well as stacks composed of conductive oxide electrodes and PZT or PLZT on top of Si (100) substrates. The electrical properties of the PZT and PLZT thin films were characterized and compared with films grown on standard Ti/Pt electrodes.