gebhart/patrepeval huggingface dataset:
The Oracle universal server buffer manager (1997)

The buffer manager is integral to the performance, scalability, and reliability of Oracle’s Universal Dam Server, a high performance object-relational database manager that provides robust data-management services for a variety of applications and tools. The rich functionality of the Universal Data Server poses special challenges to the design of the buffer manager. Buffer management algorithms must be scalable and efficient across a broad spectrum of OLTP, decision support, and multimedia workloads which impose very different concurrency, throughput and bandwidth requirements. The need for portability across a wide range of platforms further complicates buffer management; the database server must run efficiently with buffer pool sizes ranging from 50 buffers to several million buffers and on a wide variety of architectures including uniprocessors, shared-disk clusters, messagepassing MPP systems, and shared-memory muhiprocessors.
Efficacy of sustained release ciprofloxacin microspheres against device-associated Pseudomonas aeruginosa biofilm infection in a rabbit peritoneal model (1995)

The relative effectiveness of a poly(L-lactic acid) ciprofloxacin hydrochloride (CIP) microsphere formulation (250-425 microns) against peritoneal implanted biofilm of Pseudomonas aeruginosa was investigated in a rabbit model. Correlations between in-vivo CIP pharmacokinetics in peritoneal dialysate and serum after intraperitoneal administration, in-vivo cell counts and rabbit survival rate were obtained. Dialysate and serum concentrations after 12 h (C12h) were greater than those obtained with free drug whereas maximum serum concentrations (Cmax) were lower and the time to reach Cmax(tmax) was longer. A silastic implant device pre-colonised with P. aeruginosa for 2 days was implanted in the rabbit peritoneum, and dialysate with or without drug or microspheres was administered via a catheter. Rabbits receiving no antibiotic and those receiving free drug (10 mg in dialysate) died of peritonitis and septicaemia, whereas all rabbits given CIP microspheres recovered completely from infection. The viable count of P. aeruginosa was markedly reduced or eliminated from the catheter, the device and the peritoneal wall in CIP microsphere-treated rabbits but not in rabbits treated with free drug, as determined from histological and scanning electronmicroscopic evidence. These results demonstrate that sustained release of antibiotics at biofilm eradication concentrations (BEC) is required to treat biofilm infections associated with peritoneal implanted devices.
Numerical Simulation of Flow in Erlenmeyer Shaken Flask (2010)

Liu Tianzhong1, Su Ge2, Li Jing3, Qi Xiangming4 and Zhan Xiaobei3 1Qingdao Institute of Bioenergy and Bioprocess Technology, China Academy of Sciences,Qingdao 266101, 2College of Material Science and Engineering, Ocean University of China,Qingdao 266101, 3China Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, 4College of Food Science and Engineering, Ocean University of China,Qingdao 266003, China
The Beginnings and Prospective Ending of "End-to-End": An Evolutionary Perspective on the Internet's Architecture (2001)

The technology of “the Internet” is not static. Although its “end-to- end” architecture has made this “connection-less” communications system readily “extensible, ” and highly encouraging to innovation both in hardware and software applications, there are strong pressures for engineering changes. Some of these are wanted to support novel transport services (e.g. voice telephony, real-time video); others would address drawbacks that appeared with opening of the Internet to public and commercial traffic - e.g., the difficulties of blocking delivery of offensive content, suppressing malicious actions (e.g. “denial of service” attacks), pricing bandwidth usage to reduce congestion. The expected gains from making “improvements” in the core of the network should be weighed against the loss of the social and economic benefits that derive from the “end-to-end” architectural design. Even where technological “fixes” can be placed at the networks’ edges, the option remains to search for alternative, institutional mechanisms of governing conduct in cyberspace.
Parametric generation of tunable picosecond pulses in the medium infrared using AgGaS2 crystals (1984)

Infrared pulses were generated over the range from 1.2 to 10 μm in a single path system consisting of two AgGaS2 crystals. A high photon conversion efficiency between 10−1 and 10−3 was found depending upon the emission frequency. A bandwidth of approximately 10 cm−1 for idler pulses between 6 and 10 μm was observed. With a Nd:yttrium aluminum garnet laser pump of 20-ps pulse duration one observes parametric pulses of 8 ps.
New Methods for the Synthesis of 2-Aminothiazolones (2008)

Two new methods for the synthesis of 2-aminothiazolones from 2-(4-methoxybenzylthio)acetic acids are described. A single reagent and simple experimental conditions are used in the key tandem deprotection-cyclization process. In the first approach 2-aminothiazolones are directly accessed via cyclization of the corresponding N-acylisothioureas. The second complementary approach provides access to a variety of 2-thiomethylthiazolones via cyclization of N-acyldithioimidates. The product 2-thiomethylthiazolones are then efficiently converted to 2-aminothiazolones via amine displacement.
Mutant Cholinesterases Possessing Enhanced Capacity for Reactivation of Their Phosphonylated Conjugates (2004)

Selective mutants of mouse acetylcholinesterase (AChE; EC 3.1.1.7) phosphonylated with chiral S(P)- and R(P)-cycloheptyl, -3,3-dimethylbutyl, and -isopropyl methylphosphonyl thiocholines were subjected to reactivation by the oximes HI-6 and 2-PAM and their reactivation kinetics compared with wild-type AChE and butyrylcholinesterase (EC 3.1.1.8). Mutations in the choline binding site (Y337A, Y337A/F338A) or combined with acyl pocket mutations (F295L/Y337A, F297I/Y337A, F295L/F297I/Y337A) were employed to enlarge active center gorge dimensions. HI-6 was more efficient than 2-PAM (up to 29000 times) as a reactivator of S(P)-phosphonates (k(r) ranged from 50 to 13000 min(-1) M(-1)), while R(P) conjugates were reactivated by both oximes at similar, but far slower, rates (k(r) < 10 min(-1) M(-1)). The Y337A substitution accelerated all reactivation rates over the wild-type AChE and enabled reactivation even of R(P)-cycloheptyl and R(P)-3,3-dimethylbutyl conjugates that when formed in wild-type AChE are resistant to reactivation. When combined with the F295L or F297I mutations in the acyl pocket, the Y337A mutation showed substantial enhancements of reactivation rates of the S(P) conjugates. The greatest enhancement of 120-fold was achieved with HI-6 for the F295L/Y337A phosphonylated with the most bulky alkoxy moiety, S(P)-cycloheptyl methylphosphonate. This significant enhancement is likely a direct consequence of simultaneously increasing the dimensions of both the choline binding site and the acyl pocket. The increase in dimensions allows for optimizing the angle of oxime attack in the spatially impacted gorge as suggested from molecular modeling. Rates of reactivation reach values sufficient for consideration of mixtures of a mutant enzyme and an oxime as a scavenging strategy in protection and treatment of organophosphate exposure.
Conceptualizing the Mathematics Education of African American Students: Making Sense of Problems and Explanations (2015)

N/A
Double-Stacked EBG Structure for Wideband Suppression of Simultaneous Switching Noise in LTCC-Based SiP Applications (2006)

We propose a novel electromagnetic bandgap (EBG) structure with a significantly extended noise isolation bandwidth, called a double-stacked EBG (DS-EBG) structure, fabricated on a low-temperature co-fired ceramic (LTCC) multilayer substrate. The DS-EBG structure was devised for wideband suppression of simultaneous switching noise (SSN) coupling in system-in-package (SiP) applications. Our design approach was enabled by combining two EBG layers embedded between the power and ground planes. The two EBG layers had different bandgaps from using different cell sizes. Enhanced wideband suppression of the SSN coupling was validated using a 11.4-GHz noise stop bandwidth with 30-dB isolation in time and frequency domain measurements up to 20GHz.
Photoisomerization of an Individual Azobenzene Molecule in Water: An On−Off Switch Triggered by Light at a Fixed Wavelength (2006)

The alpha-hemolysin (alphaHL) pore was used as a nanoreactor for the direct observation of the reversible photoisomerization of individual tethered azobenzene molecules in an aqueous environment. alphaHL pores, PAZO, were used that had been derivatized within the lumen at a single cysteine residue with 4-((4-(2-chloroethanoamido)phenyl)diazenyl)benzenesulfonate. Trans-cis isomerizations were monitored at the single-molecule level by observing the modulation of the current passing through PAZO by electrical recording in planar bilayers. When PAZO was irradiated at 330 nm, continuous interconversion between the trans and cis states was observed. Either the trans or the cis state was maintained in the dark, depending upon which was present when the light source was shuttered. The cis state of PAZO was surprisingly stable in the dark, and no cis --> trans transitions were seen over a total observation period of more than 8 h. Therefore, based on our findings, it might be possible to make fast digital nanoscale switches operated by light of a fixed wavelength.
A novel integrated SMPS with battery backup and power factor correction (2002)

Uninterruptible energy is highly appreciated in applications such as personal computers, medical equipment, workstations, portable measurement equipment, and others. Besides, the appearance of standards about the quality of demanded line current for this equipment has been the cause of development of new power supply schemes capable of integrating battery backup and power factor correction in simple structures which offer both, low cost and size alternatives. This paper describes a novel and simple structure which offers power factor correction and battery backup capability, The proposed structure has excellent characteristics in terms of cost, size and efficiency, taking into account the reduced number of components. Experimental results of an experimental prototype of the proposed converter are included too.
A Robust and Secure Methodology for Network Communications (2010)

With the rapid development of a network multimedia environment, digital data can now be distributed much faster and easier. To maintain privacy and security cryptographic alone is not enough. In recent years, steganography has become attractive vicinity for network communications. In this paper, an attempt is made to develop a methodology which calculate the variance of secret message (which the sender wishes to send) and accordingly create a carrier file. This carrier file can be sent in any network (secure &amp; unsecure) without giving any doubt in the attackers mind. The practical implementation of this has been done on Microsoft platform. Experimental results show the feasibility of the proposed techniques.
Accumulation of hydroxyproline-rich glycoprotein mRNAs in response to fungal elicitor and infection (1985)

Hydroxyproline-rich glycoproteins (HRGPs) are important structural components of plant cell walls and also accumulate in response to infection as an apparent defense mechanism. Accumulation of HRGP mRNA in biologically stressed bean (Phaseolus vulgaris L.) cells was monitored by blot hybridization with (32)P-labeled tomato genomic HRGP sequences. Elicitor treatment of suspension-cultured cells caused a marked increase in hybridizable HRGP mRNA. The response was less rapid but more prolonged than that observed for mRNAs encoding enzymes of phytoalexin biosynthesis. HRGP mRNA also accumulated during race:cultivar-specific interactions between bean hypocotyls and the partially biotrophic fungus Colletotrichum lindemuthianum, the causal agent of anthracnose. In an incompatible interaction (host resistant) there was an early increase in HRGP mRNA correlated with expression of hypersensitive resistance; whereas, in a compatible interaction (host susceptible), marked accumulation of HRGP mRNA occurred as a delayed response at the onset of lesion formation. In both interactions, mRNA accumulation was observed in uninfected cells distant from the site of fungal inoculation, indicating intercellular transmission of an elicitation signal.
Henry James, su teoría del arte y el 'arte' de sus críticos (1983)

Henry James ocupa hoy, tanto en la conciencia del lector general como en la de los historiadores y criticos de la literatura, uno de los puestos preeminentes en el circulo celeste reservado a los autenticos genios de la creacion artistica. Para ese lector general, si esta informado, pesa mucho la opinion de tantos y tantos criticos de reconocida fama que aclaman sin reservas al novelista. Si, por el contrario, se trata de lectores desvinculados de los ambientes profesionales de la novela, raro sera que, siendo al mismo tiempo de sensibilidades menos formadas y menos exigentes, no encuentren entre la gran masa de la produccion jamesiana novelas o relatos breves capaces de entretener plenamente sus ocios y alimentar sus anhelos de fantasia. En el caso de los segundos, historiadores y criticos literarios, la unanimidad entre los que se han dedicado mas o menos de lleno al estudio de James es casi absoluta, y los pocos que han elevado la voz de la disconformidad han sido ignorados y sus esfuerzos por hacerse oir han sido vanos e impotentes entre el clamor de alabanzas de los entusiastas. Y, naturalmente, los criticos que no han estudiado particularmente la obra de James, no se encuentran en situacion distinta respecto a este, que la que ocupan los lectores informados, segun acabo de senalar. Aceptaran, por tanto, las evaluaciones de los criticos especialistas, de modo que sus referencias, siquiera marginales, al novelista se encontraran tenidas por esta impresion y de manera indirecta contribuiran a su afianzamiento en el lugar de los inmortales.
Fast dense 3D reconstruction using an adaptive multiscale discrete-continuous variational method (2014)

We present a system for fast dense 3D reconstruction with a hand-held camera. Walking around a target object, we shoot sequential images using continuous shooting mode. High-quality camera poses are obtained offline using structure-from-motion (SfM) algorithm with Bundle Adjustment. Multi-view stereo is solved using a new, efficient adaptive multiscale discrete-continuous variational method to generate depth maps with sub-pixel accuracy. Depth maps are then fused into a 3D model using volumetric integration with truncated signed distance function (TSDF). Our system is accurate, efficient and flexible: accurate depth maps are estimated with sub-pixel accuracy in stereo matching; dense models can be achieved within minutes as major algorithms parallelized on multi-core processor and GPU; various tasks can be handled (e.g. reconstruction of objects in both indoor and outdoor environment with different scales) without specific hand-tuning parameters. We evaluate our system quantitatively and qualitatively on Middlebury benchmark and another dataset collected with a smartphone camera.
Using bilingual Web data to mine and rank translations (2003)

The English Reading Wizard uses bilingual Web and local-dictionary data to help readers understand foreign languages by translating words and phrases. Methods include the expectation maximization algorithm and bilingual bootstrapping.
Smart home-based longitudinal functional assessment (2014)

In this paper, we investigate methods of performing automated cognitive health assessment from smart home sensor data. Specifically, we introduce an algorithm to quantify and track changes in activities of daily living and in the mobility of a smart home resident over time using longitudinal smart home sensor data. We use an automated activity recognition algorithm to recognize a smart home resident's activities of daily living from the generated sensor data, and introduce a Compare and Count (2C) algorithm to quantify the changes in everyday behavior. We test our approach using a longitudinal sensor dataset that we collected from 18 single-resident smart homes for nearly two years and study the relationship between observed changes in the sensor-based everyday functioning parameters and changes in standard clinical health assessment scores. The results suggest that we may be able to develop sensor-based change algorithms that can predict specific components of cognitive and physical health.
[Investigation of extracellular signal-regulated protein kinase and lymphnode metastasis in oral squamous cell carcinoma]. (2005)

Activation of ERK may play a strong role in the development of OSCC. Intensive expression of ERK protein may be an important presage marker in OSCC patients.
A Prospective Study of Laparoscopic Spinal Fusion (1996)

Laparoscopic transperitoneal anterior lumbar instrumentation and fusion is safe, and the early results are encouraging.
Strategies for Selecting and Verifying Hearing Aid Fittings (1994)

Chapter 1: Overview and Rationale for Prescriptive Formulas for Linear and Nonlinear Hearing Aids Catherine V. Palmer, Ph.D. George A. Lindley IV, Ph.D. Chapter 2: Selection, Verification, and Validation of Maximum Output H. Gustav Mueller, Ph.D. Benjamin Hornsby, M.A. Chapter 3: Real-Ear Measures Lawrence J. Revit, M.A. Chapter 4: Paired Comparisons as a Fine-Tuning Tool in Hearing Aid Fittings Francis K. Kuk, Ph.D. Chapter 5: Assessing Hearing Aid Fittings: An Outcome Measures Battery Approach Victor Bray, Ph.D. Michael Nilsson, Ph.D. Chapter 6: Fitting Strategies for Noise-Induced Hearing Loss Robert W. Sweetow, Ph.D. Rebecca Bingea, M.A. Chapter 7: Fitting Strategies for Patients with Symmetrical Hearing Loss Catherine V. Palmer, Ph.D. Chapter 8: Fitting Strategies for Patients with Asymmetrical Hearing Loss Robert E. Sandlin, Ph.D. Rose Bongiovani, M.A. Chapter 9: Fitting Strategies for Patients with Unilateral Hearing Loss Michael Valente, Ph.D. Maureen Valente, M.S Jane Enrietto, M.A. Chapter 10: Fitting Strategies for Patients with Conductive or Mixed Hearing Loss Joel Goebel, M.D. Michael Valente, Ph.D. Maureen Valente, M.S. Jane Enrietto, M.A. Mark S. Wallace, M.D. Chapter 11: Middle Ear Implants: An Alternative to Conventional Amplification Douglas A. Miller, B.S.E.E. Carol A. Sammeth, Ph.D. Chapter 12: Hearing Rehabilitation for Individuals With Severe and Profound Hearing Impairment: Hearing Aids, Cochlear Implants, and Counseling Margaret W. Skinner, Ph.D. Susan Mara Binzer, M.A. Lisa Gayle Potts, M.S. Laura Kay Holden, M.A. Roxanne J. Aaron, M.A. Chapter 13: Hearing Aid Orientation and Counseling Belinda C. Sinks, M.A. Diane F. Duddy, M.S. Chapter 14: Hearing-Aid-Related Infection Control Aukse Bankaitis, PhD Robert J. Kemp, M.B.A.
Dynamic Complexes of β2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role of Gravin (1999)

Signals mediated by G-protein-linked receptors display agonist-induced attenuation and recovery involving both protein kinases and phosphatases. The role of protein kinases and phosphatases in agonist-induced attenuation and recovery of beta-adrenergic receptors was explored by two complementary approaches, antisense RNA suppression and co-immunoprecipitation of target elements. Protein phosphatases 2A and 2B are associated with the unstimulated receptor, the latter displaying a transient decrease followed by a 2-fold increase in the levels of association at 30 min following challenge with agonist. Protein kinase A displays a robust, agonist-induced association with beta-adrenergic receptors over the same period. Suppression of phosphatases 2A and 2B with antisense RNA or inhibition of their activity with calyculin A and FK506, respectively, blocks resensitization following agonist removal. Recycling of receptors to the plasma membrane following agonist-promoted sequestration is severely impaired by loss of either phosphatase 2B or protein kinase C. In addition, loss of protein kinase C diminishes association of phosphatase 2B with beta-adrenergic receptors. Overlay assays performed with the RII subunit of protein kinase A and co-immunoprecipitations reveal proteins of the A kinase-anchoring proteins (AKAP) family, including AKAP250 also known as gravin, associated with the beta-adrenergic receptor. Suppression of gravin expression disrupts recovery from agonist-induced desensitization, confirming the role of gravin in organization of G-protein-linked signaling complexes. The Ht31 peptide, which blocks AKAP protein-protein interactions, blocks association of beta-adrenergic receptors with protein kinase A. These data are the first to reveal dynamic complexes of beta-adrenergic receptors with protein kinases and phosphatases acting via an anchoring protein, gravin.
Application of the PML Absorbing Layer Model to the Linear Elastodynamic Problem in Anisotropic Heteregeneous Media (1998)

We present and analyze a perfectly matched absorbing layer model for the velocity-stress formulation of elastodynamics. This layer has the astonishing property of generating no reflection at the interface between the free medium and the artificial absorbing medium. This allows us to obtain very low spurious reflection even with very thin layers. Several experiments show the efficiency and the generality of the model.
End stoppering in mirror machines (1976)

Like toroidal confinement, confinement by a potential barrier offers the possibility of unlimited Q if the barrier is good enough. For a barrier height PHI, approximately tau approximately equal to tau/sub collision/ exp PHI/T/sub i/. These notes review previous ideas about how to establish a potential barrier at the ends of a mirror machine and we also discuss a different possibility using mirror confinement itself to establish a barrier utilizing the positive ambipolar potential characteristic of mirror machines. One example consists of three mirrors in tandem, the two at the ends having a much smaller volume. Then mirror confinement in the end cells would be used to establish ambipolar barriers that stopper up the ends of the central, large mirror cell. An example is discussed in which, by approximate calculation, it appears that ignition might occur in a center cell 10 to 20 meters long and the overall Q is 5 or more, including the power required to sustain the end cells by neutral injection.