gebhart/patrepeval huggingface dataset:
Who is dominating whose ideology?<i>New York times</i>reporting on China (1991)

This paper explores the hegemony thesis proposed by Gramsci by a comparative analysis of the New York Times' coverage of Nixon's trip to China, 1972, and the student demonstrations at Tiananmen Square, 1989. This study begins with a review of the contending views on hegemony theory and empirical findings supporting each of these views. Following is a synthesis of quantitative and qualitative analysis of the two events with regard to the ‘actors’ and ‘acts’ in the world of texts created by these two events, and the direction of each story, whether it is favourable or unfavourable to the Chinese government, is also coded. This analysis suggests that there are three different kinds of ‘ideology’ at work in the world of texts, which are reflections of journalists' position to the dominant class, to the political bureaucracy, and to the larger social context from which journalists derive their values. To term all assumptions or values underlying the process of news production to be dominant ideology only does a disservice to our understanding of the hegemony theory.
Licofelone--clinical update on a novel LOX/COX inhibitor for the treatment of osteoarthritis (2004)

Licofelone, a competitive inhibitor of 5-lipoxygenase, cyclooxygenase (COX)-1 and COX-2, is currently in clinical development for the treatment of osteoarthritis (OA). Licofelone decreases the production of proinflammatory leukotrienes and prostaglandins-which are involved in the pathophysiology of OA and in gastrointestinal (GI) damage induced by NSAIDs-and has the potential to combine good analgesic and anti-inflammatory effects with excellent GI tolerability. Initial endoscopy data in healthy volunteers have demonstrated that licofelone is well tolerated and has a GI safety profile similar to placebo and significantly better than naproxen. These tolerability results were confirmed in patients with OA in two separate randomized studies. Furthermore, a long-term study (52 weeks) has shown that licofelone is at least as effective as naproxen in the treatment of OA. Licofelone also appears to be as effective as the selective COX-2 inhibitor celecoxib in the treatment of the signs and symptoms of OA. Licofelone has a GI safety profile similar to that of celecoxib, but may offer the advantage of fewer incidences or worsening of peripheral oedema. Preliminary data have also shown that licofelone coadministration with low-dose aspirin does not lead to increased GI toxicity. The emerging clinical data for licofelone indicate that it is an effective and well-tolerated therapy that could offer safety advantages over current treatment options, and that it could be suitable for the long-term treatment of a broad spectrum of patients with OA.
Reconciliation of process data with process simulation (1986)

Abstract The SACDA group at the University of Western Ontario has developed an equations‐oriented modular process simulation program called MASSBAL. A model of a process is constructed by selecting and flowsheeting standard building blocks describing fundamental operations such as the mixing and separating of streams. Building blocks are also provided by which equipment operating or design equations may be incorporated into the model. Reconciliation of the inconsistency and redundancy of process measurements is an optional feature of the program. The measurements are reconciled by minimizing a weighted least‐squares criterion while satisfying the model equations and any modeling constraints. The minimum is obtained directly, avoiding the need for laborious searching techniques.
Mucin-like glycoprotein secreted by cultured hamster tracheal epithelial cells. Biochemical and immunological characterization (1991)

We isolated mucin-like glycoproteins from the conditioned medium of primary hamster tracheal epithelial (HTE) cell culture and characterized them biochemically and immunologically. These glycoproteins were purified on Sepharose CL-4B after Streptomyces hyaluronidase treatment and then by CsCl-density-gradient centrifugation in the presence of 4 M-guanidinium chloride. The purified glycoproteins were resistant to digestion by chondroitin AC lyase, heparinase, heparitinase and endo-N-acetylglucosaminidases A, D and H, but susceptible to endo-beta-galactosidase and keratanase. SDS/PAGE demonstrated no contamination by low-molecular-mass proteins. The purified glycoproteins showed a peak buoyant density of 1.56 g/ml in CsCl-density-gradient centrifugation, and contained 10% peptide and 90% carbohydrate by weight. Carbohydrates in these glycoproteins contained N-acetylglucosamine, N-acetylgalactosamine, galactose, fucose, sialic acid and a trace amount of mannose, but no uronic acid. Serine and threonine together accounted for 27% of the total amino acid residues. In addition, the mucin-like glycoproteins exhibited blood-group A and B activities, and very strong inhibitory activity for influenza A virus haemagglutination. With the use of the purified glycoprotein as an antigen, six monoclonal antibodies that stained mucus granules in hamster tracheal epithelium were obtained. We characterized the antibody produced by one of the clones, HM D46. We conclude that HTE cells cultured in the serum-free medium secrete a glycoprotein with physicochemical properties similar to those known in various airways mucins.
Spin-coated silicon nanoparticle/graphene electrode as a binder-free anode for high-performance lithium-ion batteries (2012)

Si has been considered as a promising anode material but its practical application has been severely hindered due to poor cyclability caused by the large volume change during charge/discharge. A new and effective protocol has been developed to construct Si nanoparticle/graphene electrodes with a favorable structure to alleviate this problem. Starting from a stable suspension of Si nanoparticles and graphene oxide in ethanol, spin-coating can be used as a facile method to cast a spin-coated Si nanoparticle/graphene (SC-Si/G) film, in which graphene can act as both an efficient electronic conductor and effective binder with no need for other binders such as polyvinylidenefluoride (PVDF) or polytetrafluoroethylene (PTFE). The prepared SC-Si/G electrode can achieve a high-performance as an anode for lithium-ion batteries benefiting from the following advantages: i) the graphene enhances the electronic conductivity of Si nanoparticles and the void spaces between Si nanoparticles facilitate the lithium ion diffusion, ii) the flexible graphene and the void spaces can effectively cushion the volume expansion of Si nanoparticles. As a result, the binder-free electrode shows a high capacity of 1611 mA·h·g−1 at 1 A·g−1 after 200 cycles, a superior rate capability of 648 mA·h·g−1 at 10 A·g−1, and an excellent cycle life of 200 cycles with 74% capacity retention.
The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in <i>Saccharomyces cerevisiae</i> (2006)

Glutathione (GSH), L-gamma-glutamyl-L-cysteinyl-glycine, is the major low-molecular-weight thiol compound present in almost all eukaryotic cells. GSH degradation proceeds through the gamma-glutamyl cycle that is initiated, in all organisms, by the action of gamma-glutamyl transpeptidase. A novel pathway for the degradation of GSH that requires the participation of three previously uncharacterized genes is described in the yeast Saccharomyces cerevisiae. These genes have been named DUG1 (YFR044c), DUG2 (YBR281c), and DUG3 (YNL191w) (defective in utilization of glutathione). Although dipeptides and tripeptides with a normal peptide bond such as cys-gly or glu-cys-gly required the presence of only a functional DUG1 gene that encoded a protein belonging to the M20A metallohydrolase family, the presence of an unusual peptide bond such as in the dipeptide, gamma-glu-cys, or in GSH, required the participation of the DUG2 and DUG3 gene products as well. The DUG2 gene encodes a protein with a peptidase domain and a large WD40 repeat region, while the DUG3 gene encoded a protein with a glutamine amidotransferase domain. The Dug1p, Dug2p, and Dug3p proteins were found to form a degradosomal complex through Dug1p-Dug2p and Dug2p-Dug3p interactions. A model is proposed for the functioning of the Dug1p/Dug2p/Dug3p proteins as a specific GSH degradosomal complex.
54-fs, 10-GHz soliton generation from a polarization-maintaining dispersion-flattened dispersion-decreasing fiber pulse compressor (2001)

A 10-GHz train of nearly transform-limited 54-fs soliton pulses was generated by adiabatic compression of the output of a mode-locked fiber laser with a polarization-maintaining dispersion-flattened dispersion-decreasing fiber. The peak-to-pedestal ratio exceeded 23 dB. At high input powers, the pulse width was reduced to as short as 43 fs, although the wings of the pulse were degraded and the jitter increased. The compression properties are different for the two polarization axes, owing to their different dispersion characteristics. The output polarization exhibits no drift.
Dissolution Kinetics and PAG Interaction of Phenolic Resins in Chemically Amplified Resists. (1997)

This paper describes the dissolution behavior of phenolic resins and resists in aqueous base solutions as measured with a quartz crystal microbalance. The dissolution kinetics of poly(4-hydroxystyrene) is linear with time, irrespective of molecular weights and polydispersities (including tandem blends). The effects of the composition of poly(4- hydroxystyrene-co-t-butyl acrylate) (ESCAP resin) and the loading of triphenylsulfonium triflate on the dissolution kinetics have been studied, revealing that the dissolution rate exponentially decreases with increasing the acrylate and triflate contents. A longer induction period is observed at a higher acrylate and triflate concentration. The dissolution inhibition effect of acid generators has been correlated with an interaction between the phenolic OH group and an acid generator molecule as studied by 13C NMR. The strong interaction of onium salts with phenol is clearly observed also in IR spectra of the above copolymer films. The quartz c ystal microbalance has provided valuable information on the dissolution kinetics of exposed Shipley UVIIHS resist films, which exhibit a very fast dissolution of 30, 000Å/sec. The dissolution rates of the exposed resist films have been correlated with the degrees of deprotection as determined by thickness measurements, IR, and 13C NMR, and also with the rate values of authentic terpolymers of 4-hydroxystyrene, t-butyl acrylate, and acrylic acid, which had been prepared from an ESCAP copolymer.
Human surfactant protein B: structure, function, regulation, and genetic disease (1995)

Elucidation of the structure and function of the hydrophobic surfactant protein (SP-B) and the SP-B gene has provided critical insight into surfactant homeostasis and control of respiratory epithelial cell gene expression. Surfactant protein B, in concert with surfactant protein A (SP-A), surfactant protein C (SP-C), and surfactant phospholipids, contributes to the structure and function of surfactant particles, determining surface activities and pathways by which surfactant phospholipids and proteins are processed, routed, packaged, and secreted from lamellar bodies by type II epithelial cells. After secretion, SP-B plays an essential role in determining the structure of tubular myelin, the stability and rapidity of spreading, and the recycling of surfactant phospholipids. The biochemical and structural signals underlying the homeostasis of alveolar surfactant are likely mediated by interactions between the surfactant proteins and phospholipids producing discrete structural forms that vary in size, aproprotein, and phospholipid content. Distinctions in structure, protein, and size are likely to determine the function of surfactant particles, their catabolism, or recycling by alveolar macrophages and airway epithelial cells. Analysis of the genetic controls governing the SP-B gene has led to the definition of DNA-protein interactions that determine respiratory epithelial cell gene expression in general. The important role of SP-B in lung function was defined by the study of a lethal neonatal respiratory disease, hereditary SP-B deficiency, caused by mutations in the human SP-B gene.
Sift: Achieving Resource-Efficient Consensus with RDMA (2019)

Sift is a new consensus protocol for replicating state machines. It disaggregates CPU and memory consumption by creating a novel system architecture enabled by one-sided RDMA operations. We show that this system architecture allows us to develop a consensus protocol which centralizes the replication logic. The result is a simplified protocol design with less complex interactions between the participants of the consensus group compared to traditional protocols. The dissaggregated design also enables Sift to reduce deployment costs by sharing backup computational nodes across consensus groups deployed within the same cloud environment. The required storage resources can be further reduced by integrating erasure codes without making significant changes to our protocol. Evaluation results show that in a cloud environment with 100 groups where each group can support up to 2 simultaneous failures, Sift can reduce the cost by 56% compared to an RDMA-based Raft deployment.
A New Position Sensitive Detector for X-Ray Diffractometry (1992)

Abstract Position sensitive detectors provide efficient X-ray detection over large solid angles; this capability has revolutionized X-ray diffractometry by reducing data collection time. This paper describes testing of a new single-axis position sensitive detector designed to locate 0.6-2 Angstrom X-rays. Dead time, quantum efficiency, energy resolution, and spatial resolution were measured. Standard powder diffraction patterns were observed with the detector, and data sets are presented. The impact of detector performance parameters on diffraction experiments is discussed.
A simulated LC oscillator using multi-input floating-gate MOSFETS (2002)

A simulated LC oscillator is proposed using multi-input floating-gate MOSFETs. A negative resistance in the oscillator is realized by the nonlinear resistor circuit with /spl Lambda/-type I-V characteristic. Furthermore, an equivalent inductor circuit is proposed using the multi-input floating-gate MOSFET. The inductance of the circuit can be varied by controlling the external voltage. This simulated inductor is used in the LC oscillator. The resultant LC oscillator is compatible with the standard CMOS process. The oscillation frequency is theoretically driven concerning some of the parasitic capacitances of MOSFETs. Moreover, a prototype chip was fabricated using MOSIS TSMC 0.35 /spl mu/m CMOS process. The preliminary experimental results from the chip are shown.
Evaluation of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy After Single and Multiple Dosings of LY3016859 in Healthy Subjects and Patients With Diabetic Nephropathy (2018)

Two phase 1 studies (TGAA and TGAB) evaluated the safety, pharmacokinetics, pharmacodynamics, and efficacy of LY3016859 (LY), a monoclonal antibody that binds epiregulin and transforming growth factor α (TGF-α), administered intravenously or subcutaneously. In TGAA, 56 healthy subjects received a single dose of LY (0.1-750 mg intravenously, 50 mg subcutaneously) or placebo. In TGAB part A, 15 patients with diabetic nephropathy (DN) received 2 doses of LY (10-750 mg intravenously) or placebo, and in TGAB part B, 45 patients with DN received 5 doses of LY (50-750 mg intravenously) or placebo. Pharmacokinetics, pharmacodynamics, anti-LY antibodies, and change in proteinuria and albuminuria were evaluated. Single and multiple doses of LY administered 3 weeks apart were well tolerated. Pharmacokinetics were nonlinear in healthy subjects and patients with DN, indicating target-mediated drug disposition. Epiregulin level increased in both studies, and TGF-α levels increased in the TGAB study, consistent with target engagement; however, LY treatment did not significantly reduce proteinuria or albuminuria in patients with DN. There was no obvious effect of LY on the disease-related biomarkers monocyte chemoattractant protein-1, synaptopodin, or transferrin. Although LY administration resulted in a high frequency of anti-LY antibodies, pharmacokinetics, target engagement, and efficacy were not impacted.
A joint encryption and error correction method used in satellite communications (2014)

Due to the ubiquitous open air links and complex electromagnetic environment in the satellite communications, how to ensure the security and reliability of the information through the satellite communications is an urgent problem. This paper combines the AES(Advanced Encryption Standard) with LDPC(Low Density Parity Check Code) to design a secure and reliable error correction method -SEEC(Satellite Encryption and Error Correction).This method selects the LDPC codes, which is suitable for satellite communications, and uses the AES round key to control the encoding process, at the same time, proposes a new algorithm of round key generation. Based on a fairly good property in error correction in satellite communications, the method improves the security of the system, achieves a shorter key size, and then makes the key management easier. Eventually, the method shows a great error correction capability and encryption effect by the MATLAB simulation.
Performance of Convolutional Turbo Coded High-speed Portable Internet (WiBro) System (2007)

WiBro (wireless broadband), the standard of high-speed portable internet (HPI) based on OFDMA/TDD and IP network in Korea, is the subset of consolidated version of IEEE 802.16e wireless MAN standard. In this paper, the architecture and key physical layer technologies of WiBro are briefly introduced, whereas the convolutional turbo code (CTC) with high-order modulation is presented in detail. The performance of convolutional Turbo coded WiBro system with QPSK, 16QAM and 64QAM over ITU-R channel models is simulated, where pilot tones aided channel estimation and 1-tap equalization are applied. Simulation results show that the good BER performances of CTC with short code block size in WiBro systems, which facilitates the flexibility of channel resource allocation. Given the same code block size, CTC outperforms TC (turbo codes) and CC (convolutional codes).
Dengue virus-specific cross-reactive CD8+ human cytotoxic T lymphocytes (1989)

Stimulation with live dengue virus of peripheral blood mononuclear cells from a dengue virus type 4-immune donor generated virus-specific, serotype-cross-reactive, CD8+, class I-restricted cytotoxic T lymphocytes (CTL) capable of lysing dengue virus-infected cells and cells pulsed with dengue virus antigens of all four serotypes. These CTL lysed autologous fibroblasts infected with vaccinia virus-dengue virus recombinant viruses containing the E gene or several nonstructural dengue virus type 4 genes. These results demonstrate that both dengue virus structural and nonstructural proteins are targets for the cytotoxic T-cell-mediated immune response to dengue virus and suggest that serotype-cross-reactive CD8+ CTL may be important mediators of viral clearance and of virus-induced immunopathology during secondary dengue virus infections.
Glutathione Turnover in Cultured Astrocytes: Studies with [<sup>15</sup>N]Glutamate (1990)

The incorporation of [15N]glutamic acid into glutathione was studied in primary cultures of astrocytes. Turnover of the intracellular glutathione pool was rapid, attaining a steady state value of 30.0 atom% excess in 180 min. The intracellular glutathione concentration was high (20-40 nmol/mg protein) and the tripeptide was released rapidly into the incubation medium. Although labeling of glutathione (atom% excess) with [15N]glutamate occurred rapidly, little accumulation of 15N in glutathione was noted during the incubation compared with 15N in aspartate, glutamine, and alanine. Glutathione turnover was stimulated by incubating the astrocytes with diethylmaleate, an electrophile that caused a partial depletion of the glutathione pool(s). Diethylmaleate treatment also was associated with significant reductions of intraastrocytic glutamate, glycine, and cysteine, i.e., the constituents of glutathione. Glutathione synthesis could be stimulated by supplementing the steady-state incubation medium with 0.05 mM L-cysteine, such treatment again partially depleting intraastrocytic glutamate and causing significant reductions of 15N labeling of both alanine and glutamine, suggesting that glutamate had been diverted from the synthesis of these amino acids and toward the formation of glutathione. The current study underscores both the intensity of glutathione turnover in astrocytes and the relationship of this turnover to the metabolism of glutamate and other amino acids.
Experience reveals best presulfiding techniques for HDS catalysts. [Hydrodesulfurization catalysts] (1982)

Catalyst HDS/HDN activity as expressed by relative volume activity (RVA) or relative weight activity (RWA) compared to a standard catalyst is examined. Feedstock is Kuwait vacuum gas oil. Results of work with presulfiding reveals that for nonspiked presulfiding, temperature should be kept to less than 300C; temperature increase of more than 300C should be limited to less than 10C/hr.; maximum activity level is 7-8% lower than for spiked presulfiding; for H/sub 2//H/sub 2/S gas mixtures maximum activity level is 30% lower than for spiked presulfiding, especially for CoMo catalysts; and for spiked presulfiding dimethyldisulfide (DMDS) is the preferred spiking agent with dimethylsulfide (DMS) as a good second choice. Indicates that spiked presulfiding results in higher sulfur on catalyst than nonspiked presulfiding.
Mobile object recognition using multi-sensor information fusion in urban environments (2008)

Mobile vision services have recently been proposed for the support of urban nomadic users. A major issue for the performance of the service - involving indexing into a huge amount of reference images - is ambiguity in the visual information. We propose to exploit geo-information in association with visual features to restrict the search within a local context. In a mobile image retrieval task of urban object recognition, we determine object hypotheses from (i) mobile image based appearance and (ii) GPS based positioning and investigate the performance of Bayesian information fusion with respect to a geo-referenced image database (TSG-20). The results from geo-referenced image capture in an urban scenario prove a significant increase in recognition accuracy (> 10%) when using the geo-contextual information in contrast to omitting geo-information.
Anti-Human Embryonic Stem Cell Monoclonal Antibody Hesca-2 Binds to a Glycan Epitope Commonly Found on Carcinomas (2010)

Hesca-2, a monoclonal antibody (mAb) IgM raised to the human embryonic stem cell (hESC) line BG-01v, binds with high affinity (nM) to the disaccharide epitope (Galβ1-3GlcNAc) on a glycan microarray. This epitope was expressed on pluripotent progenitor hESCs in culture, but not in various differentiated cells derived from hESC based on immunofluorescence microscopy. Hesca-2 stains a limited subset of cells in adult human tissues (eg, esophagus and breast). This mAb also crossreacts in immunofluorescence microscopy studies with several human ovarian cancer cell lines and is cytotoxic to them based on the release of cytosolic enzyme lactate dehydrogenase into the media. Hesca-2 immunohistochemically stained tissue from a number of human tumors, including ovary, breast, colon, and esophageal cancer. These data suggest that Hesca-2 recognizes a surface marker found both in stem cells and certain cancer cells.