gebhart/patrepeval huggingface dataset:
The Use of Variable Inlet Guide Vanes for Automotive Gas Turbine Engine Augmentation and Load Control (1976)

<div class="htmlview paragraph">This paper presents the results of the design and development work on variable inlet guide vanes (VIGV) for use in the ERDA Upgraded Automotive Gas Turbine Engine. The feasibility of the concept of VIGV augmentation was carried out on ERDA Baseline engine hardware in compressor rig and complete engine testing.</div> <div class="htmlview paragraph">Included in the paper are discussions of this VIGV design philosophy, development logic and test results, and the critical areas of gas generator compressor and turbine matching combined with variable-nozzle power turbine and vehicle matching.</div>
Expression of regulator of G protein signalling proteins in natural killer cells, and their modulation by Ly49A and Ly49D (2005)

The small GTPase accelerators regulator of G protein signalling (RGS) proteins are important regulators of proximal signalling from G protein coupled receptors. Although natural killer (NK) cells express a number of G-protein coupled receptors, expression of RGS proteins has not been investigated. We analysed the expression of RGS proteins in rat NK cells, and detected mRNA for RGS1, RGS2, RGS5, RGS8, RGS16, and RGS18. Interestingly, when we included a panel of different leucocyte subsets, we found that RGS8 was selectively expressed by NK cells. NK cells are under control of both activating and inhibitory receptors and, utilizing a xenogeneic system where the mouse activating Ly49D or inhibitory Ly49A receptors were transfected into the rat RNK-16 cell line, the potential regulation of RGS proteins by single NK cell receptors was studied. We found that ligation of Ly49D led to a rapid and transient increase in message for RGS2, while Ly49A ligation up-regulated RGS2, RGS16, and RGS18 mRNA. Both receptors also induced a prolonged increase in RGS2 endogenous protein levels. These findings suggest that RGS proteins may be influenced by or involved in NK cell receptor events, suggesting a crosstalk between G-protein coupled receptors and NK cell receptors.
Face recognition in low-resolution videos using learning-based likelihood measurement model (2011)

Low-resolution surveillance videos with uncontrolled pose and illumination present a significant challenge to both face tracking and recognition algorithms. Considerable appearance difference between the probe videos and high-resolution controlled images in the gallery acquired during enrollment makes the problem even harden In this paper, we extend the simultaneous tracking and recognition framework [22] to address the problem of matching high-resolution gallery images with surveillance quality probe videos. We propose using a learning-based likelihood measurement model to handle the large appearance and resolution difference between the gallery images and probe videos. The measurement model consists of a mapping which transforms the gallery and probe features to a space in which their inter-Euclidean distances approximate the distances that would have been obtained had all the descriptors been computed from good quality frontal images. Experimental results on real surveillance quality videos and comparisons with related approaches show the effectiveness of the proposed framework.
Sensitive lonization Cross-Section Detector for Gas Chromatography. (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSensitive lonization Cross-Section Detector for Gas Chromatography.J. E. Lovelock, G. R. Shoemake, and A. ZlatkisCite this: Anal. Chem. 1963, 35, 4, 460–465Publication Date (Print):April 1, 1963Publication History Published online1 May 2002Published inissue 1 April 1963https://doi.org/10.1021/ac60197a035RIGHTS & PERMISSIONSArticle Views51Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (748 KB) Get e-Alerts Get e-Alerts
Differential display analysis of murine collagen‐induced arthritis: cloning of the cDNA‐encoding murine ATPase inhibitor (1997)

We used the differential display technique in order to detect a new gene involved in murine type II collagen-induced arthritis (CIA). In this study, we have identified a novel gene, IF1, whose expression level is increased during the natural course of CIA. Northern blot analyses suggest that IF1 is involved in the natural course of CIA but is not involved as a trigger of CIA. IF1 is considered to be the murine ATPase inhibitor gene for several reasons. First, IF1 shows an extremely high homology to the rat ATPase inhibitor; the highly conserved region between rat and bovine amino acid residues 22-45, which is the minimum sequence showing ATPase inhibitory activities, is also highly conserved in IF1. Second, IF1 possesses a histidine-rich region in the same area, which is thought to be important for regulation of mammalian inhibitors. Third, the tissue distribution of IF1 is very suggestive. The expression of IF1 was very strong in energetic organs such as the heart, brain and kidney, and the development of arthritis requires great amounts of ATP. As arthritis develops rapidly, the cellular ATP pool may be decreased. Before the ATP pool is exhausted, the ATPase inhibitor may serve as a brake for ATP hydrolysis. If the supply of free energy can be reduced, the inflammation of arthritis may in turn be restored. Our hypothesis is that the ATPase inhibitor is involved in regulating the inflammatory responses.
Low Strain Dynamic Properties of Filled Rubbers (1971)

Abstract Carbon black does not exist as single spherical particles but forms itself into a rodlike primary structure. These rodlike structures then form into an aggregated secondary network. This secondary network is believed to be held together by Van der Waals-London attraction forces. The decrease in shear modulus of filled rubber vulcanizates with strain is due almost certainly to these secondary forces. Special mixing techniques such as attrition of the carbon black, increased time of mixing, or the addition of chemical promoters which aim at dispersing the carbon black within the mix better are shown to decrease the value of G ′ 0 −G ′ ∞ . The absence of any modulus change with strain for unfilled vulcanizates and secondly the little change observed in values of G ′ 0 −G ′ ∞ with increasing vulcanization of the rubber when containing the same amount of carbon black confirms that the decrease in modulus with strain amplitude is in no way associated with the gum phase of the filled vulcanizate. The similarity in behavior of carbon black filled rubbers with clay/water and clay/rubber systems indicates that the decrease in modulus with amplitude is due to the breakdown of the three dimensional filler aggregates. A number of rheological studies on clay systems has confirmed that clay particles form into rigid three dimensional structures when dispersed in a medium. Evidence for the aggregated filler structure to be held together by Van der Waals-London attraction forces comes from the reasonable agreement between the experimental values for the forces required to breakdown the carbon black aggregates in paraffin oil and the forces calculated from Van den Tempel's model for flocculated solid particles in a liquid. The successful application of a domain model to the hysteretical behavior exhibited by carbon black filled vulcanizates at low strains indicates that the carbon black structure breaks down under stress but reforms to the original state when the stress is removed. This conclusion is also supported by the similarity in behavior between filled rubbers and a dendritic crystal structure of PBNA in rubber. Under the optical microscope the PBNA is seen to break down and reform under a stress-strain cycle. The breakdown and reformation of this secondary aggregated carbon black structure increases the hysteresis in filled rubber vulcanizates. Other sources of hysteresis include viscoelasticity of the polymer, crystallization, stress-softening, and changes in network structure ( e.g. , breakage of weak crosslinks). These mechanisms have been discussed in depth in previous publications. Recent work has shown, however, that the strength of a rubber is dependent on the combined effect of the different hysteretical mechanisms. The breakdown and reformation of the carbon black structure at low strains in filler reinforced rubbers therefore not only affects the heat build up, transmissibility, and fatigue behavior but also influences the failure properties of the filled vulcanizate.
Assessment of a dye permeability assay for determination of inactivation rates of Cryptosporidium parvum oocysts (1997)

The ability to determine inactivation rates of Cryptosporidium parvum oocysts in environmental samples is critical for assessing the public health hazard of this gastrointestinal parasite in watersheds. We compared a dye permeability assay, which tests the differential uptake of the fluorochromes 4'-6-diamidino-2-phenylindole (DAPI) and propidium iodide (PI) by the oocysts (A. T. Campbell, L. J. Robertson, and H. V. Smith, Appl. Environ. Microbiol. 58:3488-3493, 1992), with an in vitro excystation assay, which tests their ability to excyst and, thus, their metabolic potential and potential for infectivity (J.B. Rose, H. Darbin, and C.P. Gerba, Water Sci. Technol. 20:271-276, 1988). Formaldehyde-fixed (killed) oocysts and untreated oocysts were permeabilized with sodium hypochlorite and subjected to both assays. The results of the dye permeability assays were the same, while the excystation assay showed that no excystation occurred in formaldehyde-fixed oocysts. This confirmed that oocyst wall permeability, rather than metabolic activity potential, was the basis of the dye permeability viability assessment. A previously developed protocol (L. J. Anguish and W. C. Ghiorse, Appl. Environ. Microbiol. 63:724-733, 1997) for determining viability of oocysts in soil and sediment was used to examine further the use of oocyst permeability status as an indicator of oocyst viability in fecal material stored at 4 degrees C and in water at various temperatures. Most of the oocysts in fresh calf feces were found to be impermeable to the fluorochromes. They were also capable of excystation, as indicated by the in vitro excystation assay, and were infective, as indicated by a standard mouse infectivity assay. The dye permeability assay further showed that an increase in the intermediate population of oocysts permeable to DAPI but not to PI occurred over time. There was also a steady population of oocysts permeable to both dyes. Further experiments with purified oocysts suspended in distilled water showed that the shift in oocyst populations from impermeable to partially permeable to fully permeable was accelerated at temperatures above 4 degrees C. This sequence of oocyst permeability changes was taken as an indicator of the oocyst inactivation pathway. Using the dye permeability results, inactivation rates of oocysts in two fecal pools stored in the dark at 4 degrees C for 410 and 259 days were estimated to be 0.0040 and 0.0056 oocyst day-1, respectively. The excystation assay gave similar inactivation rates of 0.0046 and 0.0079 oocyst day-1. These results demonstrate the utility of the dye permeability assay as an indicator of potential viability and infectivity of oocysts, especially when combined with improved microscopic methods for detection of oocysts in soil, turbid water, and sediments.
Dual path instruction processing (2002)

The reasons for performance losses due to conditional branch mispredictions are first studied. Branch misprediction penalties are broken into three categories: pipeline-fill penalty, window-fill penalty, and serialization penalty. The first and third of these produce most of the performance loss, but the second is also significant. Previously proposed dual (or multi) path execution methods attempt to reduce all three penalties, but these methods are also quite complex. Most of the complexity is caused by simultaneously executing instructions from multiple paths.A good engineering compromise is to avoid the complexity of multiple path execution by focusing on methods that reduce only the pipeline and window re-fill penalties. Dual Path Instruction Processing (DPIP) is proposed as a simple mechanism that fetches, decodes, and renames, but does not execute, instructions from the alternative path for low confidence predicted branches at the same time as the predicted path is being executed. All the stages of the pipeline front-end are hidden once the misprediction is detected. This method thus targets the pipeline-fill penalty and is shown to achieve a good trade-off between performance and complexity. To reduce the window-fill penalty, we further propose the addition of a pre-scheduling engine that schedules instructions from the alternative path in an estimated execution order. Thus, after a misprediction, a high number of instructions from the alternate path can be immediately issued to execution, achieving an effect similar to very fast re-filling of the window. Performance evaluation of DPIP in a 14-stage superscalar processor (like IBM Power 4) shows an average IPC improvement of up to 10% for the bzip2 benchmark, and an average of 8% for ten benchmarks from the SPECint95 and SPECint2000 suites.
지역사회 정신보건법의 적용을 위한 정신전문 간호사의 준비과정 및 대응전략 (1997)

The final destination of the mental health care is to make the patient recover his productive social skill, forcusing on his social rehabilitation, with the basic goal of avoiding unnecessary hospitalized treatment and removing of the symptom. It also aims to strengthen the community-based mental treatment, avoiding hospitalized treatment as much as possible, thus balancing and connecting the two strategies. For hospitalized treatment should be practised only in necessary cases and partial hospitalization should be activated. As for hospitalization facilities, they should be restricted in size suitable for the treatment of patient. Mental Health Law is the nation`s effort to provide best treatment for the patients who cannot make effort to enhance the quality of life which proper treatment for himself. In this task Psychiatric-Mental Health Nurse Practitioner(PMHNP) plays an important role, together with mental illness specialist, in prevention and treatment of mental illness, mental health consulting as well as social rehabilitation of the patient. In this sense the role of PMHNP as a highly specialized personnel, must not be underestimated. In this study, the researcher tries to suggest how to widen the role of PMHNP and how to prepare for that. To approach the goal of this research, this thesis studies closely the role of the nurse, diving it into three-1) role in general, 2) role in particular in each section, 3) role as a case manger-and suggests its orientation. It also suggests the nursing management of chronic mental illness patient and the estimation and tasks of mental health nursing. The suggestions about the impending tasks of community-based mental health care in this thesis are hoped to contribute to settling the activity of PMHNP who is inevitable for the mental health of the community people.
Dibenzylbutyrolactone Lignans from Forsythia koreana Fruits Attenuate Lipopolysaccharide-Induced Inducible Nitric Oxide Synthetase and Cyclooxygenase-2 Expressions through Activation of Nuclear Factor-.KAPPA.B and Mitogen-Activated Protein Kinase in RAW264.7 Cells (2010)

Previously, we reported that dibenzylbutyrolactone lignans (DBLLs) from the fruit of Forsythia koreana NAKAI (Oleaceae) has anti-inflammatory, antioxidant, and anti-asthmatic effects. In this study, to clarify the anti-inflammatory mechanisms of DBLL, we evaluated the effects of DBLLs on lipopolysaccharide-stimulated inducible nitric oxide synthetase (iNOS) and cyclooxygenase-2 (COX-2) expressions, nitric oxide (NO) and prostaglandin E(2) (PGE(2)) productions, nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) activations, inhibitor of κB (IκB) and inhibitor of κB kinase (IKK) phosphorylations in cytosolic proteins, and cytotoxicity in Raw264.7 cells. DBLLs potently suppressed both the enzyme expression and DNA-binding activity of NF-κB. Arctiin, arctigenin (1.0 µM) and matairesinol (10 µM) inhibited the expression of iNOS by 37.71±2.86%, 32.51±4.28%, and 27.44±2.65%, respectively, and arctiin, arctigenin (0.1 µM) and matairesinol (1.0 µM) inhibited COX-2 expression by 37.93±7.81%, 26.70±4.61% and 29.37±5.21%, respectively. The inhibitory effects of DBLLs on NO and PGE(2) productions were the same patterns as those seen for the reductions in iNOS and COX-2 expression, respectively. Arctiin, arctigenin (1.0 µM) and matairesinol (10 µM) significantly (p<0.05) inhibited NF-κB DNA binding by 44.85±6.67%, 44.16±6.61%, and 44.79±5.62%, respectively, and arctiin (0.1 µM) and arctigenin (1.0 µM) significantly (p<0.05) inhibited the phosphorylation of IκB by 20.58±3.86% and 25.99±6.18%, respectively. Furthermore, arctiin, matairesinol (1.0 µM) and arctigenin (10 µM) inhibited the phosphorylation of IKK by 38.80±6.64%, 38.33±6.65%, and 38.57±8.14%, respectively. In addition, DBLLs potently inhibited the lipopolysaccharide (LPS)-induced activation of MAPKs (SAPK/c-Jun NH(2)-terminal kinase (JNK), p38, and extracellular signal receptor-activated kinase (ERK)1/2). Overall, arctiin was the most effective; its effect was nearly the same as that of 10 µM helenalin. These findings suggest that treatment with non-toxic DBLLs inhibits not only NF-κB and NF-κB-regulated protein activation, but also potently inhibits the activations of specific MAPKs.
Ligation of Endothelial α <sub>v</sub> β <sub>3</sub> Integrin Increases Capillary Hydraulic Conductivity of Rat Lung (1995)

Complement-mediated pulmonary edema results from increases in lung capillary hydraulic conductivity (Lp), possibly by receptor-mediated mechanisms. We considered the Lp effects of vitronectin and the vitronectin-containing complement complex SC5b-9, which ligate the integrin alpha v beta 3. Vitronectin, SC5b-9, and SC5b-9-enriched zymosan-activated serum all rapidly increased Lp, as determined by the split-drop technique in single lung capillaries of rat lung. The Lp increases were inhibited by a monospecific (LM609) and a polyclonal (R838) antibody against the alpha v beta 3 integrin but not by an irrelevant monoclonal antibody isotype matched with LM609, by a monoclonal antibody against the alpha v beta 5 integrin, or by preimmune rabbit serum. Vitronectin monomers failed to increase Lp. The tyrosine kinase blockers genistein and methyl 2,5-dihydroxycinnamate caused significant concentration-dependent inhibitions of Lp increases due to vitronectin and zymosan-activated serum. By contrast, the protein kinase C blocker calphostin C had no major effect. We conclude that (1) multivalent ligation of the luminally located alpha v beta 3 integrin of lung capillary endothelium increases transcapillary liquid flux, and (2) the dominant signal transduction pathway for this effect occurs through tyrosine kinase activation.
The National Infrastructure Maintenance Strategy, and its implementation : urban and rural : infrastructure (2008)

The National Infrastructure Maintenance Strategy (NIMS) was approved by Cabinet in 2006. This Strategy sets overarching policy for sector-based initiatives and describes the framework for a coordinated programme of actions. It is an essential part of government's vision of delivering infrastructure services to all. The simultaneous infrastructure investment and maintenance that will result from this Strategy will not only improve infrastructure performance and underpin the sustainability of services, but will also contribute significantly towards national and local economic growth, and create long-term jobs. Background to it, and progress with its implementation, are described in this article
Rearrangement of Gene Order in the <i>phaCAB</i> Operon Leads to Effective Production of Ultrahigh-Molecular-Weight Poly[( <i>R</i> )-3-Hydroxybutyrate] in Genetically Engineered Escherichia coli (2012)

Ultrahigh-molecular-weight poly[(R)-3-hydroxybutyrate] [UHMW-P(3HB)] synthesized by genetically engineered Escherichia coli is an environmentally friendly bioplastic material which can be processed into strong films or fibers. An operon of three genes (organized as phaCAB) encodes the essential proteins for the production of P(3HB) in the native producer, Ralstonia eutropha. The three genes of the phaCAB operon are phaC, which encodes the polyhydroxyalkanoate (PHA) synthase, phaA, which encodes a 3-ketothiolase, and phaB, which encodes an acetoacetyl coenzyme A (acetoacetyl-CoA) reductase. In this study, the effect of gene order of the phaCAB operon (phaABC, phaACB, phaBAC, phaBCA, phaCAB, and phaCBA) on an expression plasmid in genetically engineered E. coli was examined in order to determine the best organization to produce UHMW-P(3HB). The results showed that P(3HB) molecular weights and accumulation levels were both dependent on the order of the pha genes relative to the promoter. The most balanced production result was achieved in the strain harboring the phaBCA expression plasmid. In addition, analysis of expression levels and activity for P(3HB) biosynthesis enzymes and of P(3HB) molecular weight revealed that the concentration of active PHA synthase had a negative correlation with P(3HB) molecular weight and a positive correlation with cellular P(3HB) content. This result suggests that the level of P(3HB) synthase activity is a limiting factor for producing UHMW-P(3HB) and has a significant impact on P(3HB) production.
White-noise magnetization fluctuations in magnetoresistive heads (2001)

Thermal magnetization fluctuations in magnetoresistive (MR) heads for magnetic hard-disk storage are a fundamental limit on their signal-to-noise ratio. The resultant noise is essentially frequency flat (white), scales with head sensitivity as signal does, but increases inversely with sensor volume. It will impact the present course of industrial R&D efforts toward geometric scaling and increasing raw head sensitivity to achieve increased areal storage densities and data rates. Magnetization noise is shown to exceed Johnson noise in 0.4 μm sensor size, giant-MR spin-valve heads designed for ∼20 Gbit/in.2 areal storage density. The basic physics underlying the experimental results is shown to be consistent with predictions from the fluctuation–dissipation theorem.