gebhart/patrepeval huggingface dataset:
(Invited) Ionic Liquids, Superionic Glasses, Quasi-Ionic Liquids, Quasi-Liquid Ionics, All with High Conductivities but Some with Little Fluidity. Where does the Paradigm End? (2014)

We overview the field of ionic liquids from the viewpoint of the electrochemist, considering the different classes of ionic liquids, aprotic, and protic that may be produced within the fields of inorganic and organic chemistry, utilizing both aprotic and protic types and some variants on the theme of particle transfer production of ionic materials. Brief mention will be made of the possible advantages of systems that are semi-liquid, ,being crystal with respect to their centers of mass, having their rotational degrees of freedom, fully excited. Some applications in battery technology will be discussed, and some limitations will be noted.
Fluorine chemistry : a comprehensive treatment (1995)

55 alphabetically organized articles prepared by 31 leading authorities from chemical corporations, universities and research institutes.
Effects of Platelet-Rich Plasma on Proliferation and Myofibroblastic Differentiation in Human Dermal Fibroblasts (2012)

Platelet-rich plasma (PRP) is plasma that is produced from autologous blood, and its usefulness in plastic surgery and dermal wound healing has garnered attention in recent years. The aim of this study was to investigate the effects of PRP and platelet-poor plasma on the proliferation and differentiation of skin fibroblasts into myofibroblasts and on wound contraction using Western blotting, immunofluorescence staining, and collagen gels containing an embedded fibroblast model. PRP promotes proliferation of human dermal fibroblasts. PRP addition enhanced the expression of alpha-smooth muscle actin protein, a myofibroblast marker, as shown by immunofluorescence staining and Western blotting. PRP-treated groups demonstrated more marked contraction in the collagen gel model than the platelet-poor plasma and vehicle groups. PRP promotes proliferation, causes the differentiation of human dermal fibroblasts into myofibroblasts and promotes wound contraction, thus providing a potential therapeutic agent for skin wound healing.
Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma (2014)

Much controversy surrounds the cell-of-origin of mutant K-Ras (K-RasG12D)-induced lung adenocarcinoma. To shed light on this issue, we have used technology that enables us to conditionally target K-RasG12D expression in Surfactant Protein C (SPC)(+) alveolar type 2 cells and in Clara cell antigen 10 (CC10)(+) Clara cells by use of cell-type-restricted recombinant Adeno-Cre viruses. Experiments were performed both in the presence and absence of the tumor suppressor gene p53, enabling us to assess what effect the cell-of-origin and the introduced genetic lesions have on the phenotypic characteristics of the resulting adenocarcinomas. We conclude that both SPC-expressing alveolar type 2 cells and CC10-expressing Clara cells have the ability to initiate malignant transformation following the introduction of these genetic alterations. The lungs of K-Ras(lox-Stop-lox-G12D/+) and K-Ras(lox-Stop-lox-G12D/+);tumor suppressor gene Trp53(F/F) mice infected with Adeno5-SPC-Cre and Adeno5-CC10-Cre viruses displayed differences in their tumor spectrum, indicating distinct cellular routes of tumor initiation. Moreover, using a multicolor Cre reporter line, we demonstrate that the resulting tumors arise from a clonal expansion of switched cells. Taken together, these results indicate that there are multiple cellular paths to K-RasG12D-induced adenocarcinoma and that the initiating cell influences the histopathological phenotype of the tumors that arise.
Antibody to HIV-1 Tat protein, a key molecule in HIV-1 pathogenesis. A brief review. (2001)

In the last few years, literature reports have unequivocally established that the 86-101 aminoacid Tat protein, essential for an efficient viral replication, can be actively secreted by infected cells. The contribution of extracellular Tat to the progression of viral infection is underlined by the ability of neutralizing anti Tat antibody to reduce the viral load in vitro and possibly also in vivo. Considering that at least some of the effect of Tat protein seem to be the consequence of an autocrine loop and that anti Tat antibody is an efficient inhibitor of viral replication, it is reasonable to suppose that extracellular Tat play a functional role in HIV-1 infection and that HIV antibody may interfere with a possible Tat driven pathogenesis. This review explores the meaning of anti Tat antibody in vitro and in vivo and its importance to shed more light on viral pathogenesis and the recent development of Tat containing vaccine.
Achieving Gigabit Performance on Programmable Ethernet Network Interface Cards (2001)

The shift from Fast Ethernet (100Mbit/s) to Gigabit Ethernet (1000Mbit/s) did not result in the expected ten-fold increase in bandwidth at the application level. In this dissertation we make use of programmable Ethernet network cards running at gigabit speeds to identify present bottlenecks. Furthermore, we investigate the performance of the PCI bus and the throughput &quot;on-the-line&quot; when using di#erent frame sizes. The PCI bus was identified as a major bottleneck. We also propose two new techniques aimed at boosting application performance to near-gigabit levels whilst maintaining full compatibility with existing systems. The proposed techniques were implemented and yielded an 80% point-to-point transfer rate benefit whilst utilizing the existing Ethernet standard framework.
Once upon a time, i bought a movie and it played everywhere in my home (2011)

As digital media replaces analog, consumers are beginning to discover that their devices no longer interoperate in the way they are accustomed to. For example, they may find it impossible to transfer a DVR-recorded show onto a portable media player from a different manufacturer. Content creators are weary of supporting myriad ecosystems, each with different rules, restrictions, DRM systems, and file formats. To address these issues, IBM has developed the Advanced Secure Content Cluster Technology (ASCCT), which provides the highest levels of DRM protections for content owners, while at the same time being completely invisible to the user, allowing them to freely move, play, and backup content from any and all ASCCT devices within their home network. We describe the plug-and-play automatic construction of an interoperable secure cluster of heterogeneous devices using a minimal message protocol.
Testing object-oriented software systems (1990)

Article Free Access Share on Testing object-oriented software systems Authors: Thomas J. Cheatham Western Kentucky University Western Kentucky UniversityView Profile , Lee Mellinger Jet Propulsion Laboratory Jet Propulsion LaboratoryView Profile Authors Info & Claims CSC '90: Proceedings of the 1990 ACM annual conference on CooperationJanuary 1990 Pages 161–165https://doi.org/10.1145/100348.100373Online:01 January 1990Publication History 19citation1,305DownloadsMetricsTotal Citations19Total Downloads1,305Last 12 Months15Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
A Study on Coordinated Optimization of Electric Vehicle Charging and Charging Pile Selection (2018)

This paper was intended to explore the mutual influences between electric vehicle (EV) charging and charging facility planning, to establish a two-stage model for optimizing the EVs’ charging and charging piles’ selection. In the first stage, the distribution pattern of the demands for EV charging, and various EVs were effectively grouped, in order to reduce the amount of computation for solving the second stage model. The goal of the second stage was to minimize the annual investment and electricity purchasing costs on the charging piles, and the coordinated optimization was carried out for EV charging and charging pile selection. The CPLEX and IP_SOLVE packages were used in MATLAB (R2014a/64 bits) to solve the established optimization model. The simulation results showed that, compared with the scheme for selecting the charging pile under the typical charging pattern (TCP), the total cost of the charging pile could be reduced by 6.32% with a scheme under the optimized charging pattern (OCP), thereby promoting the coordinated development of both the EVs and charging facilities.
Investigating G Protein-Coupled Receptor Endocytosis and Trafficking by TIR-FM (2011)

G protein-coupled receptors (GPCRs) represent the largest and most versatile family of signaling receptors. Their actions are highly regulated, both under physiological conditions and in response to clinically relevant drugs. A key element in this regulation is control of the number of functional receptors at the cell surface. Major processes that mediate this regulation are vesicular endocytosis and exocytosis of receptors. These trafficking events involve a concerted series of steps, some of which occur on a rapid timescale similar to that of functional signaling itself. Here, we describe and discuss an optical imaging approach, based on evanescent field or total internal reflection-fluorescence microscopy (TIR-FM), to investigate receptor endocytosis and recycling at the level of discrete membrane fission and fusion events. TIR-FM facilitates the study of receptor trafficking events near the plasma membrane with much greater spatial and temporal resolution than afforded by traditional methods. TIR-FM has already provided new insight to GPCR regulation, and we believe that this method has great potential for addressing a variety of questions in GPCR biology.
Backtracking-free dictionary access method for Japanese morphological analysis (1994)

Article Free AccessBacktracking-free dictionary access method for Japanese morphological analysis Share on Author: Hiroshi Maruyama IBM Research, Tokyo Research Laboratory IBM Research, Tokyo Research LaboratoryView Profile Authors Info & Claims COLING '94: Proceedings of the 15th conference on Computational linguistics - Volume 1August 1994 Pages 208–213https://doi.org/10.3115/991886.991921Online:05 August 1994Publication History 0citation150DownloadsMetricsTotal Citations0Total Downloads150Last 12 Months40Last 6 weeks7 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
DeepCell 2.0: Automated cloud deployment of deep learning models for large-scale cellular image analysis (2018)

Deep learning is transforming the ability of life scientists to extract information from images. While these techniques have superior accuracy in comparison to conventional approaches and enable previously impossible analyses, their unique hardware and software requirements have prevented widespread adoption by life scientists. To meet this need, we have developed DeepCell 2.0, an open source library for training and delivering deep learning models with cloud computing. This library enables users to configure and manage a cloud deployment of DeepCell 2.0 on all commonly used operating systems. Using single-cell segmentation as a use case, we show that users with suitable training data can train models and analyze data with those models through a web interface. We demonstrate that by matching analysis tasks with their hardware requirements, we can efficiently use computational resources in the cloud and scale those resources to meet demand, significantly reducing the time necessary for large-scale image analysis. By reducing the barriers to entry, this work will empower life scientists to apply deep learning methods to their data. A persistent deployment is available at http://www.deepcell.org.
Plant and Animal Pathogen Recognition Receptors Signal through Non-RD Kinases (2006)

Plants and animals mediate early steps of the innate immune response through pathogen recognition receptors (PRRs). PRRs commonly associate with or contain members of a monophyletic group of kinases called the interleukin-1 receptor-associated kinase (IRAK) family that include Drosophila Pelle, human IRAKs, rice XA21 and Arabidopsis FLS2. In mammals, PRRs can also associate with members of the receptor-interacting protein (RIP) kinase family, distant relatives to the IRAK family. Some IRAK and RIP family kinases fall into a small functional class of kinases termed non-RD, many of which do not autophosphorylate the activation loop. We surveyed the yeast, fly, worm, human, Arabidopsis, and rice kinomes (3,723 kinases) and found that despite the small number of non-RD kinases in these genomes (9%-29%), 12 of 15 kinases known or predicted to function in PRR signaling fall into the non-RD class. These data indicate that kinases associated with PRRs can largely be predicted by the lack of a single conserved residue and reveal new potential plant PRR subfamilies.
Analysis of variance, normal quantile-quantile correlation and effective expression support of pooled expression ratio of reference genes for defining expression stability (2017)

Identification of a reference gene unaffected by the experimental conditions is obligatory for accurate measurement of gene expression through relative quantification. Most existing methods directly analyze variability in crossing point (Cp) values of reference genes and fail to account for template-independent factors that affect Cp values in their estimates. We describe the use of three simple statistical methods namely analysis of variance (ANOVA), normal quantile-quantile correlation (NQQC) and effective expression support (EES), on pooled expression ratios of reference genes in a panel to overcome this issue. The pooling of expression ratios across the genes in the panel nullify the sample specific effects uniformly affecting all genes that are falsely reflected as instability. Our methods also offer the flexibility to include sample specific PCR efficiencies in estimations, when available, for improved accuracy. Additionally, we describe a correction factor from the ANOVA method to correct the relative fold change of a target gene if no truly stable reference gene could be found in the analyzed panel. The analysis is described on a synthetic data set to simplify the explanation of the statistical treatment of data.
What is the Optimal Dwell Time for Maximizing Ultrafiltration with Icodextrin Exchange in Automated Peritoneal Dialysis Patients? (2006)

Icodextrin-related UF in APD patients is not related to demographic factors and does not increase significantly beyond 10 hours.
Electrical percolation in graphene–polymer composites (2018)

Electrically conductive composites comprising polymers and graphene are extremely versatile and have a wide range of potential applications. The conductivity of these composites depends on the choice of polymer matrix, the type of graphene filler, the processing methodology, and any post-production treatments. In this review, we discuss the progress in graphene-polymer composites for electrical applications. Graphene filler types are reviewed, the progress in modelling these composites is outlined, the current optimal composites are presented, and the example of strain sensors is used to demonstrate their application.
QOS provisioning in micro-cellular networks supporting multimedia traffic (2002)

We introduce an adaptive call admission control mechanism for wireless/mobile networks supporting multimedia traffic, and discuss a number of resource sharing schemes which can be used to allocate wireless bandwidth to different classes of traffic. The adaptive call admission control reacts to changing new call arrival rates, and the resource sharing mechanism reacts to rapidly changing traffic conditions in every radio cell due to mobility of mobile users. In addition, we have provided an analytical methodology which shows that the combination of the call admission control and the resource sharing schemes guarantees a predefined quality-of-service to each class of traffic. One major advantage of our approach is that it can be performed in a distributed fashion removing any bottlenecks that might arise due to frequent invocation of network call control functions.
Elpasolite scintillators. (2012)

This work was funded by the U.S. Department of Energy Office of Nonproliferation Research to develop elpasolite materials, with an emphasis on high-atomic-number rare-earth elpasolites for gamma-ray spectrometer applications. Low-cost, high-performance gamma-ray spectrometers are needed for detection of nuclear proliferation. Cubic materials, such as some members of the elpasolite family (A2BLnX6; Ln-lanthanide and X-halogen), hold promise due to their high light output, proportionality, and potential for scale-up. Using both computational and experimental studies, a systematic investigation of the compositionstructureproperty relationships of these high-atomic-number elpasolite halides was performed. The results reduce the barrier to commercialization of large single crystals or transparent ceramics, and will facilitate economical scale-up of elpasolites for high-sensitivity gamma-ray spectroscopy.
Context-based Human Activity Recognition Using Multimodal Wearable Sensors (2017)

In the past decade, Human Activity Recognition (HAR) has been an important part of the regular day to day life of many people. Activity recognition has wide applications in the field of health care, remote monitoring of elders, sports, biometric authentication, e-commerce and more. Each HAR application needs a unique approach to provide solutions driven by the context of the problem. In this dissertation, we are primarily discussing two application of HAR in different contexts. First, we design a novel approach for in-home, fine-grained activity recognition using multimodal wearable sensors on multiple body positions, along with very small Bluetooth beacons deployed in the environment. State-of-the-art in-home activity recognition schemes with wearable devices are mostly capable of detecting coarse-grained activities (sitting, standing, walking, or lying down), but cannot distinguish complex activities (sitting on the floor versus on the sofa or bed). Such schemes are not effective for emerging critical healthcare applications – for example, in remote monitoring of patients with Alzheimer's disease, Bulimia, or Anorexia – because they require a more comprehensive, contextual, and fine-grained recognition of complex daily user activities. Second, we introduced Watch-Dog – a self-harm activity recognition engine, which attempts to infer self-harming activities from sensing accelerometer data using wearable sensors worn on a subject's wrist. In the United States, there are more than 35,000 reported suicides with approximately 1,800 of them being psychiatric inpatients every year. Staff perform intermittent or continuous observations in order to prevent such tragedies, but a study of 98 articles over time showed that 20% to 62% of suicides happened while inpatients were on an observation schedule. Reducing the instances of suicides of inpatients is a problem of critical importance to both patients and healthcare providers. Watch-dog uses supervised learning algorithm to model the system which can discriminate the harmful activities from non-harmful activities. The system is not only very accurate but also energy efficient. Apart from these two HAR systems, we also demonstrated the difference in activity pattern between elder and younger age group. For this experiment, we used 5 activities of daily living (ADL). Based on our findings we recommend that a context aware age-specific HAR model would be a better solution than all age-mixed models. Additionally, we find that personalized models for each individual elder person perform better classification than mixed models.
Kinetics of reductions of substituted benzaldehydes with B-alkyl-9-borabicyclo[3.3.1]nonane (9-BBN) (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of reductions of substituted benzaldehydes with B-alkyl-9-borabicyclo[3.3.1]nonane (9-BBN)M. Mark Midland and Stephen A. ZdericCite this: J. Am. Chem. Soc. 1982, 104, 2, 525–528Publication Date (Print):January 1, 1982Publication History Published online1 May 2002Published inissue 1 January 1982https://doi.org/10.1021/ja00366a025Request reuse permissionsArticle Views392Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (476 KB) Get e-Alertsclose Get e-Alerts
Yeast Clk-1 Homologue (Coq7/Cat5) Is a Mitochondrial Protein in Coenzyme Q Synthesis (1998)

Mutations in the clk-1 gene result in slower development and increased life span in Caenorhabditis elegans. The Saccharomyces cerevisiae homologue COQ7/CAT5 is essential for several metabolic pathways including ubiquinone biosynthesis, respiration, and gluconeogenic gene activation. We show here that Coq7p/Cat5p is a mitochondrial inner membrane protein directly involved in ubiquinone biosynthesis, and that the defect in gluconeogenic gene activation in coq7/cat5 null mutants is a general consequence of a defect in respiration. These results obtained in the yeast model suggest that the effects on development and life span in C. elegans clk-1 mutants may relate to changes in the amount of ubiquinone, an essential electron transport component and a lipid soluble antioxidant.