gebhart/patrepeval huggingface dataset:
Splice effects of Er-doped fiber in Er-doped fiber amplifiers (2002)

We report the splice effects in Er-doped fibers (EDF) with a 40 m length for the gain and noise figure (NF) characteristics of an EDFA. The used EDFA consisted of a forward pumping at 1480 nm, and a signal center wavelength of 1557.3 nm. In our experiment, the maximum gain is about 26 dB. The gain and NF characteristics of the EDFA using the EDF with one or two splicing points are compared with ones of the EDFA with no splicing point in the EDF. According to some experiments so far, 1.3/spl sim/4.2 dB NF deteriorations were observed in the EDFA using an the EDF with one or two splicing points. While the gain characteristics showed some gain deterioration in the EDFA using an EDF with a splicing point. The gain deterioration was less than the NF deterioration. We surmise that the splice loss causes the gain deterioration and the NF deterioration. The NF deterioration change was observed by changing the splicing point location in the EDF.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A database of protein expression in lung cancer (2001)

We have developed a comprehensive approach to identifying molecular changes in lung cancer that includes both genomic and proteomic analyses. The related effort has produced a large amount of data pertaining to gene expression at the RNA and protein levels. As a result, we have constructed a database that contains protein expression data on lung cancer as well as other relevant data including DNA microarray derived data. A large number of proteins that are expressed in different types of lung cancer have been identified and have been correlated with the expression measures for their corresponding genes at the RNA level. The database is intended to facilitate our effort at developing novel classification schemes for lung cancer and the identification of novel markers for early diagnosis.
PD-L1 and intratumoral immune response in breast cancer (2017)

// Zhi-Qiang Wang 1, 4 , Katy Milne 1 , Heather Derocher 1, 2 , John R. Webb 1, 2 , Brad H. Nelson 1, 2, 3 and Peter H. Watson 1, 4 1 Trev & Joyce Deeley Research Centre, British Columbia Cancer Agency, Victoria, British Columbia, Canada 2 Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada 3 Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada 4 Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada Correspondence to: Peter H. Watson, email: pwatson@bccancer.bc.ca Keywords: PD-L1, CD4, CD8, CD68, breast cancer Received: March 19, 2017      Accepted: April 28, 2017      Published: May 30, 2017 ABSTRACT Purpose: PD-L1 is thought to play an important role in the antitumor immune response. In this study, we investigated the expression of PD-L1 within breast tumor subsets to better define its prognostic significance. Methods: Immunohistochemistry was performed to determine PD-L1 tumor cell expression and to enumerate CD8, CD4 and CD68 tumor-infiltrating leucocytes (TIL) in a cohort of 443 breast cancers categorized by molecular subtype. Results: Across the entire cohort, PD-L1 tumor cell expression was observed in 73/443 (16.5%) cases and associated with known indicators of poor prognosis, including low patient age, high tumor grade, ER/PR negative status, but not with outcome. However, in the Triple Negative breast cancer subset PD-L1 was associated with better recurrence free survival (RFS) especially within the Basal-like subset (Hazard ratio = 0.39, 95% CI = 0.22 - 0.86, p = 0.018). Combined PD-L1/epithelial CD8 positive status was also strongly associated with better RFS and OS (Hazard ratio = 0.12, 95% CI = 0.10 - 0.71, p = 0.010 and Hazard ratio = 0.11, 95% CI = 0.11 - 0.68, p = 0.006 respectively) in the Basal-like subgroup. Conclusions: PD-L1 expression is associated with better patient survival in Basal-like breast cancer.
A dynamic query scheduling framework for distributed and evolving information systems (2002)

The rapid growth of the wide area network technology has led to an increasing number of information sources available online. To ensure the query services to scale up with such dynamic open environments, an advanced distributed information system must provide adequate support for dynamic interconnection between information consumers and information producers, instead of just functioning as a static data delivery system. We develop a distributed query scheduling framework to demonstrate the feasibility and the benefit for supporting interoperability and dynamic information gathering across heterogeneous information sources, without relying on an integrated view predefined over the participating information sources. We outline the mechanisms developed for the main components of our distributed query scheduling framework, such as query routing and query execution planning services. We also provide a concrete example to illustrate the issues on how the information consumers' query requests are dynamically processed and linked to the heterogeneous information sources and how the query scheduling framework scales up as the number of information sources increases.
Temperature dependence of dielectric constant at 10 GHz of Na‐DNA gels (1986)

Abstract Permittivity ε′ and dielectric loss ε″ of aqueous Na‐DNA gels have been measured at 10 GHz in the temperature interval −15 to + 45°C. The experimental results are analyzed in terms of a three‐component equation (Na‐DNA, interfacial water, bulk water) and yield a value of 35 water molecules/nucleotide interacting with DNA. According to theoretical and experimental data the presence of strongly bonded and weakly bonded water is considered. The modified water exhibits a mean dielectric relaxation time two‐or threefold greater than that of bulk water.
[Stess analysis of conical telescope denture using on the prosthodontic treatment for basic teeth combined periodontal diseases] (1998)

OBJECTIVE:Periodontal splints were made both on patients with peridontal absorption of three different degrees and on normal situation respectively followed by finite element calculation.The result sugree that the stesses of the supporting tissues redistributed during mastication in accordance with different degrees of periodontal absorption.The more obvious of the pcriodontal absorption is the more stress value of the periodontal supporting tissue decrease,while those of the subbasal supporting tissues increase.
Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1 (2007)

Based on our findings we propose that overproduction of the trxB1-encoded TR in L. plantarum improves tolerance towards oxidative stress. This response coincides with simultaneous induction of a group of 16 transcripts of genes. Within this group of genes, most are associated with oxidative stress response. The obtained crossover between datasets may explain the phenotype of the trxB1-overexpression strain, which appears to be prepared for encountering oxidative stress. This latter property can be used for engineering robustness towards oxidative stress in industrial strains of L. plantarum.
Synthesis and structures of host molecules containing an Se–Se bond. Intramolecular hypervalent nature of selenium atoms in the crystal state (1990)

The first host molecules containing an Se–Se bond, 5,13,20,28-tetraoxo-3,4 : 14,15 :18,19 : 29,30-tetrabenzo-6,9,12,21,24,27-hexaoxa-1,2,16,17-tetraselenacyclotriaconta-3,14,18,29-tetraene (1) and 2,9-dioxo-3,4:7,8-dibenzo-13,15,21,24-tetraoxa-5,6-diselena-1,10-diazabicyclo[8.8.8]hexacosa-3,7-diene (2), have been synthesized and their structures have been determined by X-ray analysis.
Late stages of spinodal decomposition in binary mixtures (1979)

The influence of hydrodynamic interactions on the coarsening rate $r$ of a mist of droplets combining through diffusive coalescence is examined in detail. For a sufficiently rarified mist, the competing Lifshitz-Slyozov or evaporation-condensation mechanism is dominant, but the volume fraction of precipitate actually produced in most off-critical quench experiments probably favors direct coalescence. When the minority phase is continuous, as in a quench at the critical concentration, surface-tension effects lead to a crossover from $r\ensuremath{\sim}{t}^{\frac{1}{3}}$ to $r\ensuremath{\sim}t$, where $t$ is the time.
Crystalline metal-organic frameworks (MOFs): synthesis, structure and function (2013)

Metal-organic frameworks (MOFs) are a class of hybrid network supramolecular solid materials comprised of organized organic linkers and metal cations. They can display enormously high surface areas with tunable pore size and functionality, and can be used as hosts for a range of guest molecules. Since their discovery, MOFs have experienced widespread exploration for their applications in gas storage, drug delivery and sensing. This article covers general and modern synthetic strategies to prepare MOFs, and discusses their structural diversity and properties with respect to application perspectives.
Effective DevOps: Building a Culture of Collaboration, Affinity, and Tooling at Scale (2016)

Some companies think that adopting devops means bringing in specialists or a host of new tools. With this practical guide, youll learn why devops is a professional and cultural movement that calls for change from inside your organization. Authors Katherine Daniels and Jennifer Davis provide several approaches for improving collaboration within teams, creating affinity among teams, promoting efficient tool usage in your company, and scaling up what works throughout your organizations inflection points. Devops stresses iterative efforts to break down information silos, monitor relationships, and repair misunderstandings that arise between and within teams in your organization. By applying the actionable strategies in this book, you can make sustainable changes in your environment regardless of your level within your organization. Explore the foundations of devops and learn the four pillars of effective devopsEncourage collaboration to help individuals work together and build durable and long-lasting relationships Create affinity among teams while balancing differing goals or metrics Accelerate cultural direction by selecting tools and workflows that complement your organization Troubleshoot common problems and misunderstandings that can arise throughout the organizational lifecycleLearn from case studies from organizations and individuals to help inform your own devops journey
Cantilever surface stress sensors with single-crystalline silicon piezoresistors (2005)

We present a cantilever with piezoresistive readout optimized for measuring the static deflection due to isotropic surface stress on the surface of the cantilever [Sens. Actuators B 79(2–3), 115 (2001)]. To our knowledge nobody has addressed the difference in physical regimes, and its influence on cantilever sensors with integrated piezoresistive readout, that one finds between typical atomic force microscopy measurements and the surface stress sensors used in, e.g., biochemical measurements. We have simulated the response from piezoresistive cantilevers as a function of resistor type and placement for the two different regimes, i.e., surface stress measurements and force measurements. The model thus provides the means to specifically design piezoresistive cantilevers for surface stress measurements.
Cauldron subsidence at Ascutney Mountain, Vermont (1940)

In 1903 Daly published his classic report on Ascutney Mountain, Vermont, in which he concluded that this igneous complex was emplaced by piecemeal stoping. Since that time, however, many studies of igneous bodies have been made. Accordingly, it was deemed advisable to restudy Ascutney Mountain to see what light new information might shed on the method of intrusion. Three theories were found worthy of special consideration: forceful injection, piecemeal stoping, and cauldron subsidence. Forceful injection will not satisfactorily explain the complex for several reasons: (1) The inequidimensional bodies of the complex have their longer axes athwart the regional structure. (2) The strike and dip of the country rock have not been disturbed. (3) The folds and linear features in the country rock are regional and plunge consistently to the north at low angles. The authors believe that cauldron subsidence (ring-fracture stoping) will best explain the intrusion. Cauldron subsidence is suggested by: (1) The roughly elliptical outline of the main syenite stock of the complex; (2) the slender, arcuate screen of volcanic rocks on the west side of Ascutney Mountain; (3) the crescent‐shaped intrusion of Little Ascutney Mountain; and (4) the progressive, easterly shift of centers of successively younger intrusions.
The roto-extractor in pediatric ophthalmology. (1975)

The Roto-Extractor, designed by Nicholas Douvas, M.D., was used by the authors in 66 eyes for cataracts, secondary membranes, and persistent hyperplastic primary vitreous. The average age of the patients with congenital cataracts was 2.4 years, for traumatic cataracts 16.4 years. The pupil wal cleared well in 63 of these eyes. There was no vitreous to the wound in any of the eyes. Unplanned iridectomies and prolonged inflammation were the major complications.
Spinning of Protein Polymer Fibers (1993)

Initial studies in the production of fibers from sequence controlled protein polymers have revealed that the properties of such fibers are extremely sensitive to processing conditions. We investigated methods for extrusion of high molecular weight protein polymers consisting of repeating blocks of amino acid sequence. The amino acid sequence of blocks used to design these protein polymers were modelled from the natural fibrous proteins, silk and elastin. These blocks were utilized in various lengths and dispersities such that a set of protein polymers was produced which could be systematically varied in composition from completely silk-like to primarily elastin-like. Additionally, an amino acid sequence block which confers mammalian cell adhesion was incorporated within the silk-like polymer. Several of these protein polymers were spun into fibers. The methods used for fiber spinning did not result in fibers with any appreciable molecular orientation. The properties of these fibers are discussed.
Procedures and computer programs for telescopic mesh refinement using MODFLOW (1999)

This report presents computer programs for telescopic mesh refinement using the U.S. Geological Survey (USGS) ground-water model, MODFLOW. The performance of these computer programs has been tested in models of hypothetical and actual ground-water flow systems; however, future applications of the programs could reveal errors that were not detected in the test simulations.
Fluctuations in Pituitary FSH During the Ovulatory Cycle in the Rat and a Possible Role of FSH in the Induction of Ovulation<sup>1</sup> (1968)

Measurements of pituitary gonadotropins in adult female rats showed that a sharp drop in hypophyseal FSH occurs at approximately the same time as the proestrous drop in LH. Between the morning and late afternoon of proestrus pituitary LH and FSH both decreased by approximately 50%. A similar decrease in hypophyseal LH and FSH was found to occur in pubertal rats on the day preceding their first ovulation. In the pubertal rats FSH and LH levels continued to fall, reaching their lowest levels at estrus and subsequently rising again. The data suggest that an acute release of pituitary FSH occui’s approximately concurrently with the ovulatory surge of LH. In further experiments follicular development was initiated i n immature rats by PMS treatment and ovuia-tion was obtained in response to injections of FSH given 2 days after the PMS. It was demonstrated that the ovulation could not have been solely due to LH contamination in the injected FSH. Also, the amount of FSH required for ovulation in the PMS-primed rats was compared with the proestrous drop in hypophyseal FSH. The results suggest that an acute release of FSH at proestrus may play a significant role in the ovulatory process. (Endocrinology83: 97, 1968)
CO<sub>2</sub> Reduction on Cu at Low Overpotentials with Surface-Enhanced in Situ Spectroscopy (2016)

In situ surface-enhanced spectroscopic and reactivity investigations of the electrochemical reduction of CO2 at low overpotentials (<0.7 V) was conducted on Cu surfaces. Vibrational bands corresponding to adsorbed hydrogen (Had) and carbon monoxide (COad) on Cu have been identified at 2090 and 2060 cm–1, respectively. Spectroscopic investigations show that Had is capable of partially displacing COad; however, COad is unable to displace Had to any detectable level. The preferential adsorption of H over CO on Cu is consistent with the high selectivity toward the hydrogen evolution reaction at potentials >−0.8 V versus reversible hydrogen electrode.
Kinetics of Oily Soil Release (1971)

The kinetics of detergency of liquid and mixed (liquid-solid) oily soil from cellulosic and synthetic fabrics has been investigated. A three-step soil-release mechanism is postulated involving (a) an induction period during which soil re moval is slow, (b) a rapid soil-removal period during which the amount of soil retained decreases linearly with the loga rithm of washing time, and (c) a final period during which soil retention is essentially constant. The soil-release rate is related to the diffusion rate of water into the soiled fabric. The ability of a fabric to release soil is not related to the rate at which the liquid front of a hydrophilic liquid (water, an aqueous detergent, ethylene glycol, etc) advances on the unsoiled fabric, but to the diffusion of water into the entire capillary system of the fabric. Diffusion of water into the fiber bundle facilitates soil release. Studies were made of the release of oily soil as affected by amount of soil (0.7-87% owf), wash temperature, agitation, and viscosity of oily soil in contact with an aqueous detergent. It is shown that soil which forms a highly viscous emulsion with water or an aqueous detergent solution is especially difficult to remove by aqueous detergency. Soil removal under conditions emphasizing spontaneous soil release is compared to practical laundering, and the effect of agitation is discussed. Mechanical work causing dynamic shear and flexing can be the dominant factor in oily soil removal from hydrophobic fibers with smooth surfaces and these compensate for a slow spontaneous soil release.
Desmoplastic small round cell tumor of the ovary: A rare but devastating disease in young women (2013)

•Desmoplastic small round cell tumor of the ovary is a rare clinical entity with poor prognosis.•Accurate diagnosis utilizes a combination of histological, immunohistological, and cytogenetic findings.•This disease should be kept on the differential diagnosis in young women with widespread disease on presentation.
Shagenes A and B, New Tricyclic Sesquiterpenes Produced by an Undescribed Antarctic Octocoral (2014)

The isolation and characterization of two new tricyclic sesquiterpenoids, shagenes A (1) and B (2) are presented. These compounds were isolated from an undescribed soft coral collected from the Scotia Arc in the Southern Ocean. One- and two-dimensional NMR spectroscopy and mass spectrometry provided the data necessary to characterize the compounds and their relative stereochemical configurations. Exploration of the bioactivity of shagenes A and B found 1 active against the visceral leishmaniasis causing parasite, Leishmania donovani, with no cytotoxicity against the mammalian host.
Biomimetic organization: Octapeptide self-assembly into nanotubes of viral capsid-like dimension (2003)

The controlled self-assembly of complex molecules into well defined hierarchical structures is a promising route for fabricating nanostructures. These nanoscale structures can be realized by naturally occurring proteins such as tobacco mosaic virus, capsid proteins, tubulin, actin, etc. Here, we report a simple alternative method based on self-assembling nanotubes formed by a synthetic therapeutic octapeptide, Lanreotide in water. We used a multidisciplinary approach involving optical and electron microscopies, vibrational spectroscopies, and small and wide angle x-ray scattering to elucidate the hierarchy of structures exhibited by this system. The results revealed the hexagonal packing of nanotubes, and high degree of monodispersity in the tube diameter (244 A) and wall thickness (approximately equal to 18 A). Moreover, the diameter is tunable by suitable modifications in the molecular structure. The self-assembly of the nanotubes occurs through the association of beta-sheets driven by amphiphilicity and a systematic aromatic/aliphatic side chain segregation. This original and simple system is a unique example for the study of complex self-assembling processes generated by de novo molecules or amyloid peptides.
The Toxic Effect of Beauveria bassiana (Bals.) Vuill, on Insects (1950)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Adrenergic control of induction of type II iodothyronine5'-deiodinase activity in cultured brown adipocytes (1993)

Iodothyronine 5'-deiodinase (5'D) of mouse brown adipocytes
differentiated in cell culture was characterized in detail with
respect to the adrenergic control of its biosynthesis. The
stimulation of 5'D required mRNA and protein synthesis and was
dependent on the stage of differentiation of the cells.
Contrary to previous observations in vivo, stimulation of 5'D
in cultured brown fat-cells involves elevated cyclic AMP levels
and is mediated predominantly via beta-receptors, particularly
via the so-called beta3-adrenoceptors.
A Novel Framework for Quality-Aware Resource Management in Phased Array Radar Systems (2005)

This paper addresses the problem of operating parameter assignment to multiple real-time tasks in a phased array radar system. The objective is to maximize the resulting system utility while ensuring the schedulability of all tasks with the assigned operating parameters. For this, we propose a novel framework by integrating the existing resource management framework called QRAM (QoS-based resource allocation model) with the notion of schedulability envelope. The schedulability envelope designed offline hides the complex details of phased array antenna scheduling and provides a linear formula as its quantitative abstraction. This abstraction allows QRAM to find the optimal resource assignment without concerning the details of complex scheduling. Our experimental results show that the proposed framework can achieve significantly improved system utility compared to the existing techniques.
Proteins and satiety: implications for weight management (2008)

Highly controlled medium-term studies overcoming possible differences due to texture, timing and macronutrient exchange, and assessing satiety, energy expenditure and substrate oxidation at the same time, need to be executed with a realistic bandwidth of different types of proteins in overweight individuals in different energy balances.
On the Origin of the Color Shift in White‐Emitting OLEDs (2007)

White-emitting organic light-emitting diodes (OLEDs) notoriously suffer from brightness-dependent color shifts. Based on experimental data and fundamental considerations about charge-transport and trapping, a quantitative model is developed which gives insight into the origin of this shift and describes the experimental data extremely well. Having understood the major contribution to the spectral instability, a device architecture is designed that shows excellent color stability over a wide range of brightness levels.