gebhart/patrepeval huggingface dataset:
Flame‐retardant epoxy resins with high glass‐transition temperatures from a novel trifunctional curing agent: Dopotriol (2005)

Abstract A novel phosphorus‐containing trifunctional novolac (dopotriol) was synthesized through the addition reaction of 9,10‐dihydro‐9‐oxa‐10‐phosphaphenanthrene 10‐oxide and rosolic acid. The structure of dopotriol was confirmed with NMR spectroscopy and elemental analyses. The dopotriol was blended with phenol novolac in the ratios of 10/0, 8/2, 6/4, 4/6, 2/8, and 0/10 to serve as a curing agent for diglycidyl ether of bisphenol A. Thermal properties, such as the glass‐transition temperature, thermal decomposition temperature, and flame retardancy, moisture absorption, and dielectric properties of the cured epoxy resins were evaluated. The activity and activation energy of curing were studied with the methods of Kissinger and Ozawa by dynamic differential scanning calorimetry scans. The glass‐transition temperatures of the cured epoxy resins were 138–159 °C, increasing with the phosphorus content. This is rarely seen in the literature after the addition of a flame‐retardant element. The flame retardancy increased with the phosphorus content, and a UL‐94 V‐0 grade was achieved with a phosphorus content of 1.87%. Similar dielectric properties and moisture absorption were observed for these phosphorus‐containing epoxy resins, and this implied that the addition of phosphorus to epoxy did not affect the dielectric properties and moisture absorption. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 2862–2873, 2005
Polymeric Actuators (2014)

Actuators are materials and devices that are able to change their shape in response to changes in environmental conditions and perform mechanical work on nano-, micro-, and macroscales. Among the huge variety of different actuators, polymer-based ones are highly attractive because of a number of properties such as sensitivity to a broad range of stimuli and good mechanical properties. The goal of this review is to provide a general picture of different mechanisms and working principles of polymeric actuators as well as to show a palette of their applications.
Distribution of polyamines in methanogenic bacteria (1983)

Members of all four families of methanogenic bacteria were analyzed for polyamine concentrations. High-performance liquid chromatography analysis of dansylated cell extracts revealed typical polyamine patterns for each family. Members of Methanobacteriaceae (family I) were characterized by very low polyamine concentrations; members of Methanococcaceae (family II) were characterized by putrescine and high spermidine concentrations; members of Methanomicrobiaceae (family III) were characterized by the presence of putrescine, spermidine, and sym-homospermidine; and members of Methanosarcinaceae (family IV) contained only high concentrations of sym-homospermidine in addition to putrescine. The highest polyamine concentration was found in Methanosarcina barkeri Jülich, with 0.35% putrescine in the dry cell material. The polyamine distribution found coincides with the dendrogram based on comparative cataloguing of 16S rRNA and offers a new, rapid chemotaxonomic method for characterizing methanogenic bacteria. Variation of the growth substrates (H2-CO2, methanol, acetate, and trimethylamine) for M. barkeri resulted in quantitative but not qualitative differences in polyamine composition.
GaAs bi-directional amplifier for low cost electronic scanning array antenna (2003)

The objective of this paper is to introduce a novel solution to reduce the projected high component count for large aperture phased arrays. NGST's patent pending bidirectional amplifier topology is ideal for this application, due to its switchless operation. In addition, the size, weight, and cost of the transceiver module can be greatly reduced, since only a single amplifier is required. A GaAs based bi-directional amplifier is presented here in common-source configuration.
Problems in robotic vision (2002)

The problems and choices that are faced when designing an automated vision system are examined. The tradeoffs between the different choices are considered. Particular attention is given to digitization and sampling, the preprocessing of digital images, histograms, threshold adoption/contrast stretching, edge and boundary detection, and search methods.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Preparation of Some Acetylenic Primary Amines<sup>1</sup> (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation of Some Acetylenic Primary Amines1G. F. Hennion and Eugene G. TeachCite this: J. Am. Chem. Soc. 1953, 75, 7, 1653–1654Publication Date (Print):April 1, 1953Publication History Published online1 May 2002Published inissue 1 April 1953https://pubs.acs.org/doi/10.1021/ja01103a040https://doi.org/10.1021/ja01103a040research-articleACS PublicationsRequest reuse permissionsArticle Views325Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Drosophila insulin‐like peptide‐6 ( <i>dilp6</i> ) expression from fat body extends lifespan and represses secretion of Drosophila insulin‐like peptide‐2 from the brain (2012)

Reduced insulin/IGF signaling extends lifespan in diverse species, including Drosophila melanogaster where the genome encodes seven insulin-like peptides (dilp1-7). Of these, reduced dilp2 expressed in the brain has been associated with longevity assurance when over-expression of dfoxo in fat bodies extends lifespan. Here, we show that the insulin-regulated transcription factor dFOXO positively modulates dilp6 mRNA in adult fat body. Over-expression of dilp6 in adult fat body extends lifespan and increases longevity-associated metabolic phenotypes. Adult fat body dilp6 expression represses dilp2 and dilp5 mRNA in the brain, and the secretion of DILP2 into the hemolymph. The longevity benefit of expressing dfoxo in fat body, and the nonautonomous effect of fat body dfoxo upon brain dilp expression, is blocked by simultaneously repressing dilp6 by RNAi in fat body. dilp6 thus appears to bridge dFOXO, adipose tissue and brain endocrine function to regulate Drosophila longevity.
Continuous-Variable Blind Quantum Computation (2012)

Blind quantum computation is a secure delegated quantum computing protocol where Alice, who does not have sufficient quantum technology at her disposal, delegates her computation to Bob, who has a fully fledged quantum computer, in such a way that Bob cannot learn anything about Alice's input, output, and algorithm. Protocols of blind quantum computation have been proposed for several qudit measurement-based computation models, such as the graph state model, the Affleck-Kennedy-Lieb-Tasaki model, and the Raussendorf-Harrington-Goyal topological model. Here, we consider blind quantum computation for the continuous-variable measurement-based model. We show that blind quantum computation is possible for the infinite squeezing case. We also show that the finite squeezing causes no additional problem in the blind setup apart from the one inherent to the continuous-variable measurement-based quantum computation.
Patterns of expression of a 15K <i>β</i>-D-galactoside-specific lectin during early development of the avian embryo (1989)

We have determined, by immunohistochemical and biochemical techniques, the distribution of an endogenous beta-D-galactoside-binding lectin between the early primitive streak stage and the 5th day of embryonic development of the chick. The lectin, which was purified from the pectoral muscle of 16-day-old chick embryos, migrates on SDS-PAGE as a single polypeptide of relative molecular mass 15 x 10(3). Antibodies to this pure lectin interact with the 15K (K = 10(3) M(r)) polypeptide as well as with a 6.5K polypeptide; this second component appears to be antigenically related to the 15K lectin, as antibodies affinity purified on the 15K band recognize both polypeptides. In early stages of development, lectin immunoreactivity was present in most cells of the epiblast and hypoblast in the region of the primitive streak, while towards the edge of the area pellucida the epiblast was stained less intensely. During gastrulation, strong immunoreactivity was present also in migrating cells and in the mesoblast, while at the margin of the area pellucida the epiblast was negative. Up to the 10-somite stage, lectin immunoreactivity was present in the somites, neural tube and presumptive cardiac region; the non-neural ectoderm and the extracellular matrix were not labeled; the predominant immunoreactive component at this stage of development was the 6.5K polypeptide. Later in development, the lectin immunoreactivity gradually disappeared from the dermamyotome and nervous system to reappear conspicuously as soon as a differentiated myotome could be detected. Immunoreactivity was very high in the myotome, skeletal and cardiac muscles and transient in smooth muscles. The only region of the nervous system that continued to express the lectin throughout development was the trigeminal (semilunar) ganglion; in all regions of the nervous system, the lectin immunoreactivity disappeared early in development to be re-expressed only much later. The lining epithelium of the digestive tract and other endodermal derivatives expressed the lectin transiently. In the extraembryonic membranes, immunoreactivity to the lectin was observed in the yolk sac and in both layers of the amnion. The striking regulation of the expression of this endogenous lectin suggests that its functions are linked to cell proliferation and/or to the selective expression of a developmentally-timed cell phenotype.
Hard to find, easy to find systematics; just find them (2010)

In a manufacturing organization, every morning starts with the question: what is the yield today? The cost of wafer manufacturing being fairly constant, product yield is one of the most significant variables for profitability. With the yield paretos increasingly dominated by systematic defects, yield learning based on product test is fast becoming a fundamental requirement. For an integrated device manufacturer like IBM, product-based yield learning is even more critical as this drives technology learning as well. In this paper, we will present some of IBM's yield learning techniques and several case studies from high-volume manufacturing. These techniques extend from test data analysis, to analysis of scan-based product diagnosis results, to detailed layout analysis in conjunction with test, diagnosis and inline defect inspection data. We will discuss the increasing levels of complexity associated with the various techniques and argue that an effective yield learning strategy must comprise all of the above.
TRANSPLANTATION OF A PORTION OF THE TIBIA INTO THE SPINE FOR POTT'S DISEASE (1911)

The following is a final development, from a series of studies, on the application of osteoplasty in the treatment of Pott's disease of the spine. I was induced to undertake this experimental work on the spine, on account of the excellent operative results obtained in tuberculosis of joints elsewhere in the body where bony union with its perfect support and immobilization has caused the tuberculous process to disappear so rapidly, although only a fractional part of the tuberculous tissues was removed. This has been especially exemplified in my ankylosing operation on the hip, when applied to tuberculous ostitis of that joint, and also in erasion of the knee under similar circumstances. The fact that it is only necessary to secure bony stiffening in tuberculous joints, by operation or otherwise, in order to get a rapid disappearance of tlie tuberculous process has been emphasized very strongly in the recent writings of
Evaluation of Spring Cereal Grains and Wild <i>Triticum</i> Germplasm for Resistance to <i>Rhizoctonia solani</i> AG‐8 (2003)

Rhizoctonia root rot, caused by Rhizoctonia solani Kühn AG‐8 (Anastomosis Group 8), is a yield‐limiting disease of direct‐seeded cereals in the Pacific Northwest (PNW) region of the USA, and to date, no resistant Triticum germplasm has been identified. The objective of this research was to identify potential sources of genetic resistance among selected members of the primary, secondary, and tertiary gene pools of wheat ( Triticum aestivum L.) for use in cultivar improvement. Members of the primary gene pool {spring wheat germplasm, synthetic hexaploids, triticale (× Triticosecale spp.), Triticum turgidum var. durum (Desf.) Bowden [= T turgidum subsp. durum (Desf.) Husn.]}, secondary gene pool [ Aegilops cylindrica Host, Dasypyrum villosum (L.) P. Candargy], and tertiary gene pool ( Hordeum vulgare L.) of wheat were screened for disease response to two isolates (C1 and D2) of R solani AG‐8 in controlled environment assays. Variation for magnitude of susceptibility to both isolates was detected, but no sources of resistance were identified among primary or tertiary gene pool members. Isolate D2 generally produced more severe disease than isolate C1, with the exception of the most susceptible accessions for which both isolates caused equally severe disease. All accessions of D villosum exhibited some level of seedling resistance to isolate C1, and 73% also displayed a resistance response to isolate D2. All D villosum/ durum amphiploids, as well as Chinese Spring/ D villosum addition lines, were susceptible to both isolates. Differences in disease response between the two isolates suggest that varying levels of virulence, or aggressiveness, exist among R solani AG‐8 isolates.
Epitope specificity of murine and human bactericidal antibodies against PorA P1.7,16 induced with experimental meningococcal group B vaccines (1997)

Synthetic peptides derived from the predicted loops 1 and 4 of meningococcal PorA, sero-subtype P1.7,16, were used to study the epitope specificity of murine and human PorA P1.7,16 bactericidal antibodies. The predicted loops 1 and 4 are surface exposed and carry in their apices the sero-subtype epitopes P1.7 (loop 1) or P1.16 (loop 4), respectively. Peptides were synthesized as mono- and multimeric peptides. Murine monoclonal and polyclonal antibodies were induced with meningococcal whole cell preparations. Polyclonal antibodies were evoked in volunteers after one immunization with 50 micrograms or 100 micrograms protein of a hexavalent meningococcal PorA vesicle vaccine. The induction of PorA antibodies was determined in ELISA using purified PorA P1.7,16. The epitope specificity of anti-PorA antibodies for both murine and human antibodies could be demonstrated by direct peptide ELISA using overlapping multimeric peptides almost spanning the entire loops 1 or 4 of the protein. The capacity of peptides to inhibit the bactericidal activity of murine and human antibodies was investigated using meningococcal strain H44/76 (B:15:P1.7,16) as a target strain. Bactericidal activities could be inhibited with both monomeric and multimeric peptides derived from epitopes P1.7 and P1.16.
Targeting Treg cells in cancer immunotherapy (2019)

Foxp3-expressing regulatory T (Treg) cells, which are indispensable for preventing autoimmunity, also suppress effective tumor immunity. Treg cells abundantly infiltrate into tumor tissues, which is often associated with poor prognosis in cancer patients. Removal of Treg cells enhances anti-tumor immune responses but may also elicit autoimmunity. A key issue in devising Treg-targeting cancer immunotherapy is, therefore, how to specifically deplete Treg cells infiltrating into tumor tissues without affecting tumor-reactive effector T cells, while suppressing autoimmunity. This can be achieved by differentially controlling Treg and effector T cells by various ways. In this review, we discuss how tumor-infiltrating Foxp3<sup>+</sup> Treg cells hamper effective anti-tumor immune responses especially in tumor tissues and how they can be specifically targeted for augmenting tumor immunity but not autoimmunity.
Flavonoids — novel lead compounds for the development of P2Y<sub>2</sub> receptor antagonists (2003)

Abstract A series of 40 flavonoids were investigated as antagonists at P2Y 2 receptors expressed in NG108‐15 cells (mouse neuroblastoma×rat glioma hybrid cell line) in a functional assay measuring the inhibition of UTP‐stimulated intracellular calcium release. Several flavonoids were identified as potent antagonists at P2Y 2 receptors with IC 50 values in the low micromolar concentration range; they were similarly potent or more potent than the standard P2Y 2 antagonists Reactive Blue 2 and suramin. Flavone derivatives proved to be more potent than flavanones. The flavone derivatives catechin and epicatechin were inactive. However, a bicyclic benzopyranone ring system was found to be not an absolute prerequisite for P2Y 2 antagonism, since the chalcone derivative β‐oxo‐aurentiacin ( 14 ) was also relatively potent (IC 50 19 µM). Investigated flavone glycosides were completely inactive. The most potent P2Y 2 receptor antagonists of the present series were kaempferol ( 19 ), heptamethoxyflavon ( 29 ), and tangeretin ( 25 ), with IC 50 values between 6–19 µM. Increased lipophilicity by introducing (additional) methyl groups did not generally increase antagonistic potency. Structure–activity relationships proved to be complex. Concentration–response curves for the P2Y 2 agonist UTP were not shifted to the right in the presence of increasing concentrations of tangeretin ( 25 ), and EC 50 values for UTP were not affected by the antagonist, but the amplitude of the response was reduced, indicating allosteric antagonism. In conclusion, we have identified flavonoids as novel lead structures for the development of noncompetitive antagonists at P2Y 2 receptors, which may be of interest as potential antiinflammatory drugs. Drug Dev. Res. 59:72–81, 2003. © 2003 Wiley‐Liss, Inc.
Phase structure, microstructure, and electrical properties of bismuth modified potassium-sodium niobium lead-free ceramics (2007)

( K 0.5 Na 0.5 ) 1 − 3 x Bi x NbO 3 (KNBN) ceramics were prepared by conventional solid-state sintering without cold-isostatic pressing. The phase structure, microstructure, and electrical properties of KNBN ceramics are studied. The phase structure of KNBN ceramics (x=0.01) is pure perovskite phase with orthorhombic symmetry at room temperature. The addition of Bi3+ significantly improves electrical properties of (K0.5Na0.5)NbO3 ceramics while keeping the tetragonal-orthorhombic phase transition temperature above 170 °C. The KNBN (x=0.01) ceramics show the optimum electrical properties (d33=164 pC∕N, kp=0.47, Qm=120, TC=403 °C, TO-T=174 °C, Pr=30.1 μC∕cm2, and Ec=6.18 kV∕cm). Take into account electrical properties and the polymorphic phase transition temperature (TO-T), it can be concluded that the KNBN (x=0.01) ceramic is a promising lead-free piezoelectric candidate material for practical application. The related mechanisms for high piezoelectric properties in KNBN (x=0.01) ceramics are also discussed.
Novel methods to incorporate photosensitizers into nanocarriers for cancer treatment by photodynamic therapy (2011)

Post-loading is the promising method for loading nanoparticles with hydrophobic photosensitizers to achieve effective in vitro and in vivo PDT.
Multiple adverse thyroid and metabolic health signs in the population from the area heavily polluted by organochlorine cocktail (PCB, DDE, HCB, dioxin) (2009)

Significantly higher accumulation of adverse signs in subjects with high POPs level was found in POLL thus supporting the conclusion that POPs appear to increase the prevalence of several subclinical and overt thyroid and metabolic disorders.
Emigration of activated leukocytes augments transvascular permeability in mesenteric venules of rat. (1992)

Effects of leukocyte adhesion and emigration on the microvascular permeability were analyzed by the combined use of high resolution transilluminated intravital microscopy and the epiilluminated fluorescent tracer imaging. After stimulating leukocytes by topical application of PAF-LPS or fMLP solution on the mesentery of a rat, a dynamic process of leukocyte emigration was visualized under high resolution transilluminated microscopic observation. When considerable emigration of leukocytes was observed, the same microvasculature was subjected to a permeability study to visualize the diffusional process of the FITC-labeled macromolecules under an epiilluminated fluorescent microscope. Dye diffusion was accelerated in the PAF-LPS or fMLP-treated group, and also a distinctly spotty leakage was observed in venules where successive adhesion and emigration of leukocytes were observed.
House Body House (2021)

Abstract The essay describes Carolee Schneemann's residence, a stone house constructed in 1750 by Huguenot settlers on land of the Munsee Lenape people, and its central role in her life and work from the early 1960s until her death in 2019. The essay gives particular attention to Schneemann's text “Parts of a Body House” (1957–67), a series of paragraphs composed over a decade that describe a network of biomorphic structures and multimedia environments. The essay argues that “Parts of a Body House” is a “nerve codex” by which to read the artist's life and work. The essay is derived in part from remarks the author delivered at the memorial service for Schneemann at Judson Memorial Church, New York, on 3 May 2019.
Toward a modern concept of sepsis: new answers to ancient questions. (2006)

It is commonly thought that bacterial endotoxin such as lipopolysaccharide (LPS) causes sepsis. Authors argue that LPS is merely a disease marker. The real mechanism of sepsis lies in the Toll-like receptors that suppress sepsis caused by tissue injury or endotoxin. When Toll-like receptors' initial suppression role is overwhelmed, sepsis ensues.
A Survey of Causes of Bovine Abortion Occurring in the San Joaquin Valley, California (1990)

The causes of abortion in cattle in the San Joaquin Valley of California were surveyed from submissions to the California Veterinary Diagnostic Laboratory at Tulare. Four hundred sixty-eight abortion cases were examined. Most submissions (89%) were from large drylot dairies, milking an average of 814 cows. Abortion evaluations included necropsy, histopathology, bacteriology, virology, and other immunologic and serologic tests. A specific cause was identified in 29.5% of the abortions. Bacterial infections, most of which were sporadic, accounted for 16% of all abortions. Viral causes and protozoal infections were diagnosed in 5.6% and 3.2% of the abortions, respectively. Fetuses with protozoal infection had histologic lesions of focal nonsuppurative necrotizing encephalitis, and protozoa were detected. Similar histologic lesions were seen in 80 additional fetuses (17.1%), and although an etiologic agent was not identified for these cases, a protozoal infection was suspected.
A Convenient Synthesis of 2-Arylmethylindoles (1992)

Methoxy substituted arenes 2 were alkylated with 1-benzenesulfonyl-2-bromomethyl-3-phenylthioindole (1) using palladium chloride to give the alkyl substituted arenes 3, which on Raney nickel followed by sodium hydroxide treatment gave 2-arylmethylindoles 4 in good yield.