gebhart/patrepeval huggingface dataset:
Burst frame synchronization for OFDM transmission in multipath fading links (1999)

We present an improved burst frame synchronization method for orthogonal frequency division multiplexing (OFDM) systems. In the proposed method, we use the training data inserted in both the time and frequency domains to perform burst frame synchronization for OFDM transmission. Specifically, the supplementary guard interval inserted in the time domain is used for coarse frame synchronization, and the pilot sub-carriers inserted in the frequency domain are used to further improve the coarse frame synchronization accuracy. It is demonstrated that the proposed burst frame synchronization method can be done within one OFDM symbol period. In addition, it is shown that significant performance improvement can be achieved when the proposed scheme is used.
New lens system for surface vibrational spectroscopy at high impact energies (1984)

The design, characterization, and performance of a new lens system which permits high-resolution electron energy-loss spectroscopy (EELS) studies at high energies is described. The lens system can be adapted to most existing EELS instruments and extends the impact energy range to 300 eV. Electron ray-tracing techniques are used to characterize operating modes of one of the more common EELS optics designs as well as the new lens configuration. The results presented in this paper demonstrate some limitations of matrix optics approaches and the applicability of electron ray-tracing techniques for characterizing the transmission properties, angular profiles, image sizes, and operating modes of EELS spectrometers.
Abnormal Cortisol Metabolism and Tissue Sensitivity to Cortisol in Patients with Glucose Intolerance (2002)

Recent evidence suggests that increased cortisol secretion, altered cortisol metabolism, and/or increased tissue sensitivity to cortisol may link insulin resistance, hypertension, and obesity. Whether these changes are important in type 2 diabetes mellitus (DM) is unknown. We performed an integrated assessment of glucocorticoid secretion, metabolism, and action in 25 unmedicated lean male patients with hyperglycemia (20 with type 2 diabetes and 5 with impaired glucose intolerance by World Health Organization criteria) and 25 healthy men, carefully matched for body mass index, age, and blood pressure. Data are mean +/- SE. Patients with hyperglycemia (DM) had higher HbA(1c) (6.9 +/- 0.2% vs. 6.0 +/- 0.1%, P < 0.0001) and triglycerides. Cortisol secretion was not different, as judged by 0900 h plasma cortisol and 24 h total urinary cortisol metabolites. However, the proportion of cortisol excreted as 5alpha- and 5beta-reduced metabolites was increased in DM patients. Following an oral dose of cortisone 25 mg, generation of plasma cortisol by hepatic 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD 1) was impaired in DM patients (area under the curve, 3617 +/- 281 nM.2 h vs. 4475 +/- 228; P < 0.005). In contrast, in sc gluteal fat biopsies from 17 subjects (5 DM and 12 controls) in vitro 11beta-HSD 1 activity was not different (area under the curve, 128 +/- 56% conversion.30 h DM vs. 119 +/- 21, P = 0.86). Sensitivity to glucocorticoids was increased in DM patients both centrally (0900 h plasma cortisol after overnight 250 micro g oral dexamethasone 172 +/- 16 nM vs. 238 +/- 20 nM, P < 0.01) and peripherally (more intense forearm dermal blanching following overnight topical beclomethasone; 0.56 +/- 0.92 ratio to vehicle vs. 0.82 +/- 0.69, P < 0.05). In summary, in patients with glucose intolerance, cortisol secretion, although normal, is inappropriately high given enhanced central and peripheral sensitivity to glucocorticoids. Normal 11beta-HSD 1 activity in adipose tissue with impaired hepatic conversion of cortisone to cortisol suggests that tissue-specific changes in 11beta-HSD 1 activity in hyperglycemia differ from those in primary obesity but may still be susceptible to pharmacological inhibition of the enzyme to reduce intracellular cortisol concentrations. Thus, altered cortisol action occurs not only in obesity and hypertension but also in glucose intolerance, and could therefore contribute to the link between these multiple cardiovascular risk factors.
Formulation of oral dosage forms by three dimensional printing (1998)

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1998.
Effects of Antiglaucoma Drugs on Ocular Blood Flow in Ocular Hypertensive Rabbits (1993)

Antiglaucoma drugs were studied systematically on the ocular blood flow in ocular hypertensive rabbits. As expected, pilocarpine, clonidine and acetazolamide were all found to increase the ocular blood flow in the retina and choroid. However, their use in the clinics was much less than the beta-blockers, such as L-timolol, levobunolol, betaxolol and metipranolol. It was surprising to find that all non-specific and beta 1-specific adrenergic blockers decreased the ocular blood flow in ocular hypertensive rabbits. If this finding holds true in human patients, the use of beta-blockers for glaucoma treatment should be reconsidered. Dopamine antagonists, such as droperidol, metoclopramide and loxapine, were found to increase the ocular blood flow. Therefore, they might be able to replace beta-blockers for glaucoma treatment.
Compact battery-less information terminal (CoBIT) for location-based support systems (2002)

The target of ubiquitous computing environment is to support users to get necessary information and services in a situation-dependent form. Therefore, we propose a location-based information support system by using Compact Battery-less Information Terminal (CoBIT). A CoBIT can communicate with the environmental system and with the user by only the energy supply from the environment. It has a solar cell and get a modulated light from an environmental optical beam transmitter. The current from the solar cell is directly (or through passive circuit) introduced into an earphone, which generates sound for the user. The current is also used to make vibration, LED signal or electrical stimulus on the skin. The sizes of CoBITs are about 2cm in diameter, 3cm in length, which can be hanged on ears conveniently. The cost of it would be only about 1 dollar if produced massively. The CoBIT also has sheet type corner reflector, which reflect optical beam back in the direction of the light source. Therefore the environmental system can easily detect the terminal position and direction as well as some simple signs from the user by multiple cameras with infra-red LEDs. The system identifies the sign by the modulated patterns of the reflected light, which the user makes by occluding the reflector by hand. The environmental system also recognizes other objects using other sensors and displays video information on a nearby monitor in order to realize situated support.
Matched-field minimum variance beamforming in a random ocean channel (1992)

Matched-field source localization methods that employ deterministic full-wave acoustic propagation models can be seriously degraded due to the presence of random inhomogeneities in the ocean channel. In this paper, a minimum variance (MV) matched-field beamformer is presented that achieves greater robustness to random inhomogeneities in the sound-speed profile between the source and receiver. The proposed modification of the MV beamformer consists of employing multiple linear constraints derived from predicted pressure fields obtained using a set of perturbed sound-speed profiles. In order to investigate the nature of wave-front variations due to random sound-speed perturbations, a normal mode model based on adiabatic and first-order perturbation approximations is examined. The signal wave-front spatial correlation implied by this model suggests that the coherence among modes can remain high even in a fluctuating ocean environment. This in turn implies that the dimension of the signal perturbation constraint space for the MV beamformer can be small for typical sound-speed variations at moderate source ranges. Given the signal constraint space, design of the MV beamformer with sound-speed perturbation constraints is achieved by selecting its quiescent response to maximize the average signal-to-noise ratio gain against spatially uncorrelated noise. This leads to a computationally efficient realization of the beamformer that avoids the need to repeatedly compute perturbed pressure fields. Simulation experiments using a realistic deep-water Pacific Ocean environment are presented, which suggest that robust unambiguous low-frequency source location estimates can be achieved in the presence of mesoscale inhomogeneities given only knowledge of the second-order statistics of the random range-dependent sound-speed profile plus a single environmental measurement at the receiving array.
Fabrication of high aspect ratio Si nanogratings with smooth sidewalls for a deep UV-blocking particle filter (2007)

To measure space plasmas and neutral particles one must filter out high-energy ultraviolet photons that would increase background count or damage sensors. To enable sensitive neutral particle measurements, a photon-to-particle rejection rate of 1014 is desired, far exceeding the requirements of prior filters. The authors propose a high-aspect ratio Si grating with densely packed, sub-100 nm slits. In this article, the authors report the development of a new technique for fabricating sturdy, self-supported transmission gratings in silicon using nanoimprint lithography and deep reactive ion etching, resulting in grating slits with scalloping under 7 nm and high (8.5:1) aspect ratios.
Pichinde Virus Infection in Strain 13 Guinea Pigs Reduces Intestinal Protein Reflection Coefficient with Compensation (1990)

Pichinde virus inoculation into strain 13 guinea pigs is a model with features reputed to be similar to hemorrhagic fever in humans. Although the infection is lethal by day 13-19, guinea pigs of approximately 600 g do not show edema or effusions. This raises the questions of whether capillary damage is present in such infected animals and, if it is, why edema is absent. The effects of Pichinide virus on protein transport across jejunal capillaries were examined in 38 normal and 7 infected strain 13 guinea pigs 12 days after inoculation. The latter lost 20.3% body weight but maintained normal blood pressure, serum protein concentration, and jejunal lymph flow. However, their protein solvent drag reflection coefficient (sigma) was reduced to .52 +/- .03 (mean +/- SE) from .73 +/- .02 (2P less than .001), while permeability-surface area product was not changed. In the absence of gross edema or effusions, Pichinde virus-infected guinea pigs demonstrated a leaky gut capillary wall to protein compatible with an increase in pore size or large pore number less than sufficient to change permeability-surface area product. Compensatory mechanisms that prevent edema at this stage are efficient and may include reduced capillary pressure or some degree of capillary flow stasis.
Serial Susceptibility Weighted MRI Measures Brain Iron and Microbleeds in Dementia (2009)

A new iron sensitive MR sequence (susceptibility weighted imaging - SWI) enabling the simultaneous quantitation of regional brain iron levels and brain microbleeds (BMB) has been acquired serially to study dementia. Cohorts of mildly cognitively impaired (MCI) elderly (n = 73) and cognitively normal participants (n = 33) have been serially evaluated for up to 50 months. SWI phase values (putative iron levels) in 14 brain regions were measured and the number of BMB were counted for each SWI study. SWI phase values showed a left putaminal mean increase of iron (decrease of phase values) over the study duration in 27 participants who progressed to dementia compared to Normals (p = 0.035) and stable MCI (p = 0.01). BMB were detected in 9 out of 26 (38%) MCI participants who progressed to dementia and are a significant risk factor for cognitive failure in MCI participants [risk ratio = 2.06 (95% confidence interval 1.37-3.12)]. SWI is useful to measure regional iron changes and presence of BMB, both of which may be important MR-based biomarkers for neurodegenerative diseases.
MCL-1 is a prognostic indicator and drug target in breast cancer (2018)

Analysis of publicly available genomic and gene expression data demonstrates that MCL1 expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl-2 family members, the short half-life of MCL-1 protein led us to investigate MCL-1 protein expression in a breast cancer tissue microarray and correlate this with clinical data. Here, we report associations between high MCL-1 and poor prognosis in specific subtypes of breast cancer including triple-negative breast cancer, an aggressive form that lacks targeted treatment options. Deletion of MCL-1 in the mammary epithelium of genetically engineered mice revealed an absolute requirement for MCL-1 in breast tumorigenesis. The clinical applicability of these findings was tested through a combination of approaches including knock-down or inhibition of MCL-1 to show triple-negative breast cancer cell line dependence on MCL-1 in vitro and in vivo. Our data demonstrate that high MCL-1 protein expression is associated with poor outcome in breast cancer and support the therapeutic targeting of MCL-1 in this disease.
Surface Imaging Using Photoinduced Acid-Catalyzed Formation of Polysiloxanes at Air—Polymer Interface (1995)

Polysiloxane formation by a chemical vapor deposition (CVD) method on the UV-irradiated surface of polymer films was studied. Polymers which have both 4-vinylbiphenyl (4-VB) units and 1,2,3,4-tetrahydro-1-naphthylideneamino p-styrenesulfonate (NISS) units were synthesized. When the irradiated surface of the polymer films was exposed to the vapor of alkoxysilanes at 30 °C, polysiloxane networks were formed on the surface. No polysiloxane networks were formed in the unirradiated areas. The thickness of the polysiloxane layer which is formed beneath the film surface was reduced by the existence of 4-VB unit in the polymers because the 4-VB units worked as a UV absorbent. The photoinduced acid-catalyzed crosslinking of polymers containing NISS and glycidyl methacrylate effectively decreased the thickness of the polysiloxane network layer beneath the film surface because of the reduced diffusible depth of alkoxysilane vapor into the film. The polymer films which were irradiated and subsequently exposed to the vapor of alkoxysilanes showed a good resistance to etching using an oxygen plasma.
Effect of Diabetes Mellitus on Female Sexual Function and Risk Factors (2005)

The study was conducted to investigate the effect of diabetes mellitus upon female sexual function, and to detect possible risk factors that might predict sexual dysfunction. The study consisted of 127 married women: 21 women with type 1 diabetes, 50 women with type 2 diabetes and 56 healthy women as a control. Female sexual functions were evaluated with a questionnaire to assess sexual desire, arousal, lubrication, orgasm, satisfaction and pain. The prevalence of sexual dysfunction was 71% in the type 1 diabetic group, 42% in the type 2 diabetic group and 37% in the control subjects. The scores for sexual desire, arousal and lubrication were significantly lower in the type 1 diabetes group than in the control subjects (p < 0.05). The scores of orgasm, satisfaction, dyspareunia and total sexual function were slightly lower in the type 1 diabetic group than in the other groups. No factor predicted sexual dysfunction in the diabetic women while further age, poor education, absence of occupation and menopause predicted sexual dysfunction in the control subjects. The prevalence of sexual dysfunction was significantly higher in the type 1 diabetic women than in the type 2 diabetics and control subjects. However, no risk factors that might cause sexual dysfunction could be predicted in diabetic women.
Synthesis of (silylamino)phosphines by the Wilburn method (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of (silylamino)phosphines by the Wilburn methodRobert H. Neilson and Patty Wisian-NeilsonCite this: Inorg. Chem. 1982, 21, 9, 3568–3569Publication Date (Print):September 1, 1982Publication History Published online1 May 2002Published inissue 1 September 1982https://pubs.acs.org/doi/10.1021/ic00139a059https://doi.org/10.1021/ic00139a059research-articleACS PublicationsRequest reuse permissionsArticle Views148Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Operation of a VBL memory write gate (1985)

A write gate for the VBL memory was designed and fabricated on an as-grown garnet wafer supporting 5 μm bubbles. Pictures of the transient stripe during the write operation were taken showing the effectiveness of the gate design in controlling the stripe head motion and the generation of the VBL's in the head, There are two regions of operational margin for the expanding current, one is between 23 and 48 mA, with 500 to 700 nsec pulse width, the other is between 68 and 92 mA. with 300 to 700 nsec pulse width. The operation of the write gate is independent of the in-plane field.
Some Results on Cylindrical Cavity Resonators (1947)

Certain hitherto unpublished theoretical results on cylindrical cavity resonators are derived. These are: an approximation formula for the total number of resonances in a circular cylinder; conditions to yield the minimum volume circular cylinder for an assigned Q; limitation of the frequency range of a tunable circular cylinder as set by ambiguity; resonant frequencies of the elliptic cylinder; resonant frequencies and Q of a coaxial resonator in its higher modes; and a brief discussion of fins in a circular cylinder. The essential results are condensed in a number of new tables and graphs.
Microgrid Enabled Distributed Energy Solutions (MEDES) - Fort Bliss Military Reservation (2014)

Abstract : The Microgrid Enabled Distributed Energy Solutions (MEDES) demonstration project is the first Department of Defense (DoD) grid-tied microgrid to integrate renewable resources, on-site generation, and energy storage with facility loads and the utility distribution network. As prime contractor, Lockheed Martin designed and built the microgrid system, intelligently integrating distributed diesel generation, solar photovoltaic (PV) array, and grid-scale energy storage with the medium voltage utility grid and facility loads at one of the Brigade Combat Team (BCT) Complexes at Fort Bliss. Currently the United States (U.S.) power grid is largely centralized with a handful of large utilities handling the majority of power production in the country. In 1996, a sagging power line in Oregon brushed up against a tree, and then within minutes, 12 million electricity customers in eight states lost power. Such is the vulnerability of the aging U.S. power grid. In order to remedy this systemic risk from large scale blackouts a new more decentralized system can be used in which a cluster of on-site power generation devices/assets can service local loads in the event of power loss from the Utility. A microgrid is a localized set of generation, energy storage, and loads that normally operate connected to a traditional utility grid. There is a single point of common coupling with the utility grid that can be disconnected if the microgrid needs to be able to operate without utility power in the event of utility failure. The primary benefit of a microgrid is energy surety/resiliency/mission sustainment; however there can be advantages in found in energy cost savings depending on one s electric rate structure. The Energy Manager needs to fully understand their electric provider s rate structure and the load profile of their facilities in order to effectively design a microgrid to help in energy costs.
Conical refraction: an experimental introduction (2008)

We outline some general properties of the conerefracted (CR) beam - a beam passed along an optic axis of biaxial crystal. The intensity of the incident beam is assumed to have a propagation <i>z</i>-axis of cylindrical symmetry and a symmetry plane <i>z</i> = 0. The CR beam also has a symmetry plane <i>Z</i> = 0 and two kinds of axial symmetries with common <i>Z</i>-axis; besides, it possesses two focal planes <i>Z</i> = ±<i>Z</i><sub>F</sub>. The familiar light ring is best resolved at <i>Z</i> = 0. Some of the beam transformation rules can be "seen" as known from the geometrical or Gaussian optics. We present for the first time experiments with two consecutive crystal elements. In this case the exit beam splits in two CR beams and their parameterization is given by explicit formulas. The experimentally deduced rules are simple but not trivial.
Thermoresponsive cyclodextrins with switchable inclusion abilities (2012)

Cyclodextrins (CDs) modified with oligoethylene glycols (OEGs) show unprecedented thermoresponsive properties in aqueous solutions and their phase transition temperatures can be mediated in the range of 24–63 °C depending on the ring size of CDs and the structure of the OEG units. Their synthesis, thermoresponsive behavior, and host-guest chemistry are described herein. Similar to the native CDs, these CD derivatives display strong inclusion ability for dyes below the phase transition temperatures. Moreover, the encapsulated dyes can be easily released due to the dehydration of OEG units at elevated temperatures, associated with an obvious color change of the aqueous solutions, which makes these CD species unique as scaffolds for colorimetric sensors.
A generalized discrepancy and quadrature error bound (1998)

An error bound for multidimensional quadrature is derived that includes the Koksma-Hlawka inequality as a special case. This error bound takes the form of a product of two terms. One term, which depends only on the integrand, is defined as a generalized variation. The other term, which depends only on the quadrature rule, is defined as a generalized discrepancy. The generalized discrepancy is a figure of merit for quadrature rules and includes as special cases the<inline-formula content-type="math/mathml"><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="script upper L Superscript p"><mml:semantics><mml:msup><mml:mrow class="MJX-TeXAtom-ORD"><mml:mrow class="MJX-TeXAtom-ORD"><mml:mi class="MJX-tex-caligraphic" mathvariant="script">L</mml:mi></mml:mrow></mml:mrow><mml:mi>p</mml:mi></mml:msup><mml:annotation encoding="application/x-tex">{\mathcal L}^p</mml:annotation></mml:semantics></mml:math></inline-formula>-star discrepancy and<inline-formula content-type="math/mathml"><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="upper P Subscript alpha"><mml:semantics><mml:msub><mml:mi>P</mml:mi><mml:mi>α</mml:mi></mml:msub><mml:annotation encoding="application/x-tex">P_\alpha</mml:annotation></mml:semantics></mml:math></inline-formula>that arises in the study of lattice rules.