gebhart/patrepeval huggingface dataset:
Migration of Human Gingival Fibroblasts Over Guided Tissue Regeneration Barrier Materials (1996)

The purpose of this investigation was to determine the ability of human gingival fibroblasts, in vitro, to migrate along a chemotactic gradient over 3 different guided tissue regeneration barrier materials; i.e., polytetrafluoroethylene, polylactic acid, and sterile calcium sulfate. Forty petri dishes were divided into 4 equal groups. In each group of 10 dishes, a different barrier material served as the fibroblast substrate with the polystyrene floor of one group of Petri dishes serving as the control. The under agarose technique of measuring cell migration was employed using platelet derived growth factor-BB homodimer as the chemoattractant and Hanks balanced salt solution to test random migration. In addition, fibroblasts were directly cultured on triplicate sets of barrier materials and the control surface for 24 hours and examined by scanning electron microscopy. Comparative analysis of the fibroblast migration data showed the mean migration distance (adjusted for random migration) for controls to be significantly greater than any of the three barrier materials. Further, mean migration distance over calcium sulfate was significantly greater when compared to that of the polylactic acid barrier group. All other comparisons between groups were not statistically significant. Scanning electron microscopic examination fibroblasts cultured directly on barrier membranes and compared to controls indicated that the calcium sulfate substrate appeared to facilitate cell attachment and spreading whereas cells on polytetrafluoroethylene and polylactic acid barriers exhibited a morphology not conducive to migration or, in many cases, cell health. Based on these limited in vitro results and, given the 3 barrier materials considered, it would appear that calcium sulfate offers the greater potential for guided tissue regeneration in surgical sites where primary wound closure cannot be obtained.
A JBIG arithmetic coder-decoder chip (2003)

A Joint Bilevel Image Experts Group (JBIG) arithmetic coder-decoder chip is presented. In addition to arithmetic coding, the chip also performs probability estimation for adaptation. With a 40-MHz clock, this half-duplex chip can process 8 Mb of raw data per second. The throughput is the same for both encode and decode operations, and is independent of the compression ratio. The chip is fabricated using a CMOS 1- mu m compacted array technology. Tests indicate that the chip is fully functional.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Speech and text-image processing in documents (1993)

Two themes have evolved in speech and text image processing work at Xerox PARC that expand and redefine the role of recognition technology in document-oriented applications. One is the development of systems that provide functionality similar to that of text processors but operate directly on audio and scanned image data. A second, related theme is the use of speech and text-image recognition to retrieve arbitrary, user-specified information from documents with signal content. This paper discusses three research initiatives at PARC that exemplify these themes: a text-image editor[1], a wordspotter for voice editing and indexing[12], and a decoding framework for scanned-document content retrieval[4]. The discussion focuses on key concepts embodied in the research that enable novel signal-based document processing functionality.
Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins (2010)

A novel type of isobaric internal peptide standard for quantitative proteomics is described. The standard is a synthetic peptide derived from the target peptide by positional permutation of two amino acids. This type of internal standard is denominated minimally permutated peptide analog (MIPA). MIPA can be differentiated from their target analytes by LC-MS due to individual retention times and/or by MS/MS due to specific fragment ions. Both quantification methods are demonstrated using peptide mixtures of low and high complexity.
Lens Gap Junctions in Growth, Differentiation, and Homeostasis (2010)

The cells of most mammalian organs are connected by groups of cell-to-cell channels called gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins. There are at least 20 isoforms of connexins, and most tissues express more than 1 isoform. The lens is no exception, as it expresses three isoforms: Cx43, Cx46, and Cx50. A common role for all gap junctions, regardless of their Cx composition, is to provide a conduit for ion flow between cells, thus creating a syncytial tissue with regard to intracellular voltage and ion concentrations. Given this rather simple role of gap junctions, a persistent question has been: Why are there so many Cx isoforms and why do tissues express more than one isoform? Recent studies of lens Cx knockout (KO) and knock in (KI) lenses have begun to answer these questions. To understand these roles, one must first understand the physiological requirements of the lens. We therefore first review the development and structure of the lens, its numerous transport systems, how these systems are integrated to generate the lens circulation, the roles of the circulation in lens homeostasis, and finally the roles of lens connexins in growth, development, and the lens circulation.
UAV-Assisted Water Quality Monitoring (2020)

Water quality assessment for the management of water resources requires the collection of water samples for physical, chemical, and biological analysis. It is essential to reduce the cost of water quality monitoring by minimizing the number of grab samples and to reduce the sampling time by rapidly accessing the sampling points. Adaptive, remote, and smart water sampling systems can provide more effective water quality monitoring programs. An adaptive water sampling system with an unmanned aerial vehicle integrated with sensor nodes was developed and tested in this research. Individual phases of this research were; in-situ water quality measurements with a UAV-integrated sensor node; autonomous water sample collection with a UAV-integrated water sampler; and integration of water sampler and sensor node sub-systems for UAV-assisted adaptive water sampling. The UAV-assisted adaptive water sampling system consists of a hexacopter UAV, a triple water sampling cartridge, and a sensor node. The payload capacity and endurance of the UAV were determined using an indoor test station. The UAV was able to hover 10 min while producing 64 N of thrust at 4.61 kg of takeoff weight with no payload attached. The thrust-to-weight ratio of the UAV was measured as 1.41 at 50% throttle level. The adaptive water sampling method depended on computerbased automated decision making. The decision to activate the water sampling cartridge for water sample collection was made based on pH, dissolved oxygen (DO), electrical conductivity (EC), and temperature sensor inputs from the sensor node. The adaptive sampling enabled selective water sample collection only when the water constituent measurements exceeded the assigned allowable limits during indoor tests. Field experiments were conducted to test the systems to achieve adaptive water sampling from a 1.1 ha fishing pond and a 11 ha portion of a 36 ha lake. Instantaneous decision making for sample collection based on in-situ pH, DO, EC and temperature measurements would eliminate unnecessary water sample collection while providing data with high spatial resolution for assessing water quality in surface waters.
In‐Situ Coating of Silica Nanoparticles with Acrylate‐Based Polymers (2007)

Abstract Nanoscale oxide/polymer composites consisting of a silica core coated with either methylmethacrylate (MMA) or ethyl‐2‐cyanoacrylate (ECA) are produced in‐situ by chemical vapor synthesis (CVS). In this process, a hot‐wall reactor is used for the preparation of the oxide core, followed by a plasma reactor to form the polymer coating. Deposition of the coating material was confirmed using nitrogen adsorption, X‐ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), high‐resolution transmission electron microscopy (HRTEM), X‐ray photoelectron spectroscopy (XPS), and thermal analysis (TGA). The influence of the monomer on the dispersability in polar and non‐polar media was investigated by photon correlation spectroscopy (PCS).
Human thymus contains amnion epithelial antigens. (1983)

Antibodies produced in rabbits to detergent-solubilized human amnion were found to react with Hassall's corpuscles in human thymus. Following nomenclature for placental antigens, the immunogenic group responsible for these antibodies has been tentatively designated as amnion antigens 1 (AA1). The anti-AA1 antisera did not react with other thymic components, nor did they react with any other extra-embryonic tissues than amniotic epithelium. Some adult ectodermally derived tissues, such as breast ductal and corneal epithelium, reacted with anti-AA1, but others such as skin and vagina did not. These findings link an antigenic relationship between amniotic epithelium and certain ectodermal derivatives. Amnion exists long before these tissues are formed, raising the possibility that amniotic epithelium may play an inductive role in their development.
Micromechanical bending of single collagen fibrils using atomic force microscopy (2007)

A new micromechanical technique was developed to study the mechanical properties of single collagen fibrils. Single collagen fibrils, the basic components of the collagen fiber, have a characteristic highly organized structure. Fibrils were isolated from collagenous materials and their mechanical properties were studied with atomic force microscopy (AFM). In this study, we determined the Young's modulus of single collagen fibrils at ambient conditions from bending tests after depositing the fibrils on a poly(dimethyl siloxane) (PDMS) substrate containing micro-channels. Force-indentation relationships of freely suspended collagen fibrils were determined by loading them with a tip-less cantilever. From the deflection-piezo displacement curve, force-indentation curves could be deduced. With the assumption that the behavior of collagen fibrils can be described by the linear elastic theory of isotropic materials and that the fibrils are freely supported at the rims, a Young's modulus of 5.4 +/- 1.2 GPa was determined. After cross-linking with glutaraldehyde, the Young's modulus of a single fibril increases to 14.7 +/- 2.7 GPa. When it is assumed that the fibril would be fixed at the ends of the channel the Young's moduli of native and cross-linked collagen fibrils are calculated to be 1.4 +/- 0.3 GPa and 3.8 +/- 0.8 GPa, respectively. The minimum and maximum values determined for native and glutaraldehyde cross-linked collagen fibrils represent the boundaries of the Young's modulus.
Design Issues of Peer-to-Peer Systems for Wireless Ad Hoc Networks (2007)

Peer-to-peer is a popular distributed system. Mobile ad hoc networks and peer-to-peer file sharing systems both lack fixed infrastructure and hold no a- priori knowledge of arriving and departing peers. Due to this common nature, P2P file sharing seems natural and attractive to be deployed for MANET. But, the resource constraints such as bandwidth, computing power, energy, etc. and node's mobility give hard challenges to the researchers. Smart content distribution and efficient content discovery are the heart of p2p protocol that controls the performance of the system. Routing is associated with every task that is expensive in ad hoc environment. In this paper, we address these issues and present a guideline to design mobile peer-to-peer systems.
Magnetic susceptibility artifacts in magnetic resonance imaging: calculation of the magnetic field disturbances (1996)

In magnetic resonance imaging, inhomogeneities of the static magnetic field lead to perturbations in the resulting images, called artifacts. The authors' goal is to compute numerically the disturbances induced by a material having magnetic properties different from that of the surrounding tissues. The method is linked to an artifact reconstruction model to get simulated images. This model needs very accurate results in a fine three-dimensional grid around the implant. The use of standard methods would lead to solve very large systems. The authors' method is based on a surface integral representation of the magnetic field. To implement it in an efficient way, an analytical expression is derived when the boundary of the domain can be meshed in flat panels. For curved surfaces a numerical quadrature scheme is implemented.
Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring (2009)

To discover novel delta-opioid receptor ligands derived from SNC80 (1), a series of 6,8-diazabicyclo[3.2.2]nonane derivatives bearing two aromatic moieties was prepared, and the affinity toward delta, mu, and kappa receptors, as well as sigma receptors, was investigated. After removal of the 4-methoxybenzyl and 2,4-dimethoxybenzyl protecting groups, the pharmacophoric N,N-diethylcarbamoylbenzyl residue was attached to the 6,8-diazabicyclo[3.2.2]nonane framework to yield the designed delta receptor ligands. In a first series of compounds the benzhydryl moiety of SNC80 was dissected, and one phenyl ring was attached to the bicyclic framework. In a second series of delta ligands the complete benzhydryl moiety was introduced into the bicyclic scaffold. The determined delta receptor affinities show that compounds based on an (R)-glutamate-derived bicyclic scaffold possess higher delta receptor affinity than their (S)-glutamate-derived counterparts. Furthermore, an intact benzhydryl moiety leads to delta receptor ligands that are more potent than compounds with two separated aromatic moieties. Compound 24, with the same spatial arrangement of substituents around the benzhydryl stereocenter as SNC80, shows the highest delta receptor affinity of this series: K(i)=24 nM. Whereas the highly potent delta ligands reveal good selectivity against mu and kappa receptors, the sigma(1) and/or sigma(2) affinities of some compounds are almost in the same range as their delta receptor affinities, such as compound 25 (sigma(2): K(i)=83 nM; delta: K(i)=75 nM). In [(35)S]GTPgammaS assays the most potent delta ligands 24 and 25 showed almost the same intrinsic activity as the full agonist SNC80, proving the agonistic activity of 24 and 25. The enantiomeric 4-benzylidene derivatives 15 and ent-15 showed selective cytotoxicity toward the 5637 (bladder) and A-427 (small-cell lung) human tumor cell lines.
Snorre TLP Tethers and Foundation (1991)

ABSTRACT The mooring system for the Snorre TLP, including four concrete foundation templates and tether components for the 16 tether strings is described. The design requirements are listed, and the significant development and testing work to document function, strength and reliability of the various components are also presented with emphasis on key results and comparison with theoretical predictions. Manufacturing and installation aspects of foundations and tether components are also presented, highlighting the very strict requirements to manufacturing and installation tolerances in order to meet the design requirements. INTRODUCTION One of the most challenging aspects of a TLP project is the development of the mooring system, which is of vital importance for the safety and structural reliability of the entire TLP. It is, therefore, of importance that all aspects related to loading, structural behaviour and resistance of the mooring system are considered in detail at an early stage of the development, and that sufficient overcapacity and redundancy is built in to allow some margins for unforeseen changes in later project phases. This paper describes the work related to development of the mooring system for the Snorre TLP, i.e. the foundations and the tethers. Most of the paper is concentrated on the work to develop and document a structurally sound and safe mooring system, while aspects related to fabrication and installation are more briefly covered. MOORING SYSTEM DESCRIPTION The Snorre TLP mooring system is based on a through column installation method with mooring flat tie-off above water level (Fig. 1). It consists of a total of 16 tether strings, 4 in each corner of the TLP. Each group of 4 tethers is anchored to one concrete foundation template (CFT) on the seabed. Each CFT has a multicelled geometry with skirts penetrating 12 meters into the seabed (Fig. 2). In the upper part, the skirts are closed by a dome structure, and in the centre part above the domes, a prestressed solid concrete section provides the support for the tether anchoring components (abutment rings), which are cast and reinforced into the concrete structure for transfer of tether loads. The outer skirt walls are extended above the domes forming retaining walls for the solid ballast which is placed in compartments on top of the domes. The CFTs will be installed with the tether anchoring supports at the same elevation, and the inclined seabed is compensated for by preadjusting the height of the center solid part of the different CFTs according to the actual seabed topography. The anchor latch assembly (Fig. 3) provides the means of securing the tether to the CFT. The assembly consists of the anchor latch and the template insert which is the receptacle in the foundation. The loads are transferred from the anchor latch through the template insert to the abutment ring. An important part of the anchor latch is the flexelement (Fig. 5) which accommodates the angular displacement of the tether at the seafloor and, therefore, prevents excessive bending stresses in the tether string itself.
The <i>hrp</i> gene locus of <i>Pseudomonas solanacearum</i>, which controls the production of a type III secretion system, encodes eight proteins related to components of the bacterial flagellar biogenesis complex (1995)

Five transcription units of the Pseudomonas solanacearum hrp gene cluster are required for the secretion of the HR-inducing PopA1 protein. The nucleotide sequences of two of these, units 1 and 3, have been reported. Here, we present the nucleotide sequence of the three other transcription units, units 2, 4 and 7, which are together predicted to code for 15 hrp genes. This brings the total number of Hrp proteins encoded by these five transcription units to 20, including HrpB, the positive regulatory protein, and HpaP, which is apparently not required for plant interactions. Among the 18 other proteins, eight belong to protein families regrouping proteins involved in type III secretion pathways in animal and plant bacterial pathogens and in flagellum biogenesis, while two are related solely to proteins involved in secretion systems. For the various proteins found to be related to P. solanacearum Hrp proteins, those in plant-pathogenic bacteria include proteins encoded by hrp genes. For Hrp-related proteins of animal pathogens, those encoded by the spa and mxi genes of Shigella flexneri and of Salmonella typhimurium and by the ysc genes of Yersinia are involved in type III secretion pathways. Proteins involved in flagellum biogenesis, which are related to Hrp proteins of P. solancearum, include proteins encoded by fli and flh genes of S. typhimurium, Bacillus subtilis and Escherichia coli and by mop genes of Erwinia carotovora. P. solanacearum Hrp proteins were also found to be related to proteins of Rhizobium fredii involved in nodulation specificity.
Asymmetric Base-Catalyzed Diels-Alder Reaction of 3-Hydroxy-2-Pyrone with <i>N</i>-Methylmaleimide (1996)

Abstract An asymmetric base-catalyzed Diels-Alder reaction of 3-hydroxy-2-pyrone with N-methylmaleimide was achieved by using cinchona alkaloids as asymmetric catalysts. The reaction catalyzed by cinchonidine afforded endo-adduct in 77% ee, and opposite enantiomer of 71% ee was obtained with cinchonine.
Murine model of ocular infection by a human biovar of Chlamydia trachomatis. (1995)

Several strains of inbred mice are susceptible to human chlamydial biovars and may provide a useful alternative disease model in which to study the immunopathogenesis of ocular chlamydial infection and test of vaccine candidates derived from clinically relevant human biovars.
Marketing Research and Information Systems (1997)

Marketing research and information systems , Marketing research and information systems , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
The Molecular basis of smell and taste transduction (1993)

Partial table of contents: Receptor Diversity and Spatial Patterning in the Mammalian Olfactory System (L. Buck). Molecular Mechanisms of Olfactory Neuronal Gene Regulation (M. Wang & R. Reed). A New Tool for Investigating G Protein-Coupled Receptors (M. Lerner, et al.). Second Messenger Signaling in Olfaction (H. Breer). Membrane Currents and Mechanisms of Olfactory Transduction (S. Firestein & F. Zufall). Perireceptor Events in Taste (H. Schmale, et al.). Role of Apical Ion Channels in Sour Taste Transduction (S. Kinnamon). Ion Pathways in the Taste Bud and Their Significance for Transduction (J. DeSimone, et al.). Indexes.
ChemInform Abstract: Recent Advances in Matrix Metalloproteinase Inhibitors Research (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A combined project planning model for documentation/training at BNR (1994)

Bell-Northern Research (BNR) is a global leader in the design and development of advanced telecommunications systems and products. Documentation and training groups at BNR have historically been autonomous; that is until last year. Both organizations have now integrated under one management team. With this association was the understanding that the new organization would encounter a number of problems; for example, differences concerning culture, processes, and functions.
Treatment of Four Biorefractory Contaminants in Soils Using Catalyzed Hydrogen Peroxide (1991)

Abstract The treatment of soil contaminated with pentachlorophenol, trifluralin [2,6‐dinitro‐ N , N ‐dipropyl‐4‐(trifluoromethyl) benzenamine], hexadecane, and dieldrin (3,4,5,6,9,9‐hexachloro‐1 a ,2,2 a ,3,6,6 a ,7,7 a ‐octahydro‐2,7:3,6‐dimethanonaphth[2,3‐b]oxirene) using catalyzed hydrogen peroxide [H 2 0 2 and iron(II)] was investigated in a soil of low development with organic C ranging from 2000 mg kg –1 to 16 000 mg kg –1 . Soil treatment was conducted at pH 3 with 240 and 400 mg L –1 iron additions and 120 000 mg L –1 H 2 O 2 . Pentachlorophenol and trifluralin degradation rates decreased as a function of soil organic C content. However, soil organic C had no effect on the degradation rates of dieldrin and hexadecane. In addition, the four contaminants degraded at equal rates with soil containing organic C > 10 000 mg kg –1 . The ratio of first‐order rate constants for contaminant degradation to hydrogen peroxide consumption (k contaminant /k h 2 O 2 ) was used as an empirical measure of treatment efficiency. These ratios were sensitive to both the soil organic C content and to the concentration of iron added during treatment. The efficiency ratios were highest for treatment with no iron addition; these data suggest that iron minerals and H 2 O 2 provide a system in which Fenton‐like oxidations are catalyzed. The ability of iron minerals and H 2 O 2 to oxidize pentachlorophenol was evaluated in goethite‐, hematite‐, and magnetite‐silica sand at pH 3. Pentachlorophenol was degraded in the mineral‐silica sand systems, which was verified by the loss of organic C and the stoichiometric recovery of chloride.