gebhart/patrepeval huggingface dataset:
Distinct evolutionary patterns of<i>Oryza glaberrima</i>deciphered by genome sequencing and comparative analysis (2011)

Here we present the genomic sequence of the African cultivated rice, Oryza glaberrima, and compare these data with the genome sequence of Asian cultivated rice, Oryza sativa. We obtained gene-enriched sequences of O. glaberrima that correspond to about 25% of the gene regions of the O. sativa (japonica) genome by methylation filtration and subtractive hybridization of repetitive sequences. While patterns of amino acid changes did not differ between the two species in terms of the biochemical properties, genes of O. glaberrima generally showed a larger synonymous-nonsynonymous substitution ratio, suggesting that O. glaberrima has undergone a genome-wide relaxation of purifying selection. We further investigated nucleotide substitutions around splice sites and found that eight genes of O. sativa experienced changes at splice sites after the divergence from O. glaberrima. These changes produced novel introns that partially truncated functional domains, suggesting that these newly emerged introns affect gene function. We also identified 2451 simple sequence repeats (SSRs) from the genomes of O. glaberrima and O. sativa. Although tri-nucleotide repeats were most common among the SSRs and were overrepresented in the protein-coding sequences, we found that selection against indels of tri-nucleotide repeats was relatively weak in both African and Asian rice. Our genome-wide sequencing of O. glaberrima and in-depth analyses provide rice researchers not only with useful genomic resources for future breeding but also with new insights into the genomic evolution of the African and Asian rice species.
Ensemble methods for sentiment analysis of on-line micro-texts (2016)

Now a days, the Twitter has become a most trusted platform of on-line micro-texts (tweets) for monitoring the public sentiment for any entity (events, topic or products). In recent years, many approaches have been used for sentiment analysis of on-line micro-texts in a manner to predict the public opinion for real world entities. However, the accuracy of prediction is highly dependent on the accuracy of the sentiment analysis. The consistent performance of the multiple classifiers (ensembles) approaches in many applications of classification promotes the use of an ensemble of classifiers for sentiment analysis of on-line micro-texts too. Therefore, while considering the sentiment analysis of on-line micro-texts as a task of classification in machine learning, this paper investigates for the sovereignty of ensemble methods over other methods for the task and discusses the various setting of ensembles for the sentiment analysis of on-line micro-texts.
Development of MGs in a next generation network with MEGACO/H.248 support (2005)

Transport services and connection control evolution make it possible that voice, data and image networks converge into one unique network. The MEGACO/H.248 protocol is the first protocol developed as the cooperative effort of IETF and ITU-T, two important standardization groups. By using Petri net as the description technique, this paper shows the design, validation and tests of a MEGACO based next generation network (NGN).
Signal-dependent correlation-sensitive branch metrics for Viterbi-like sequence detectors (2002)

By applying the Euclidian branch metric in a Viterbi-like detector when the noise is signal-dependent and correlated, the receiver falls short of the maximum likelihood sequence detector (MLSD). We introduce new signal-dependent correlation-sensitive branch metrics for Viterbi-like implementations of the MLSD. We also provide an analytic analysis that calculates the probability of error of such a detector and compares it to the performance of the Euclidian detector. The new metric is well suited for magnetic recording applications where, especially at high recording densities, the noise is both correlated and signal-dependent.
Shakespeare and Nashe (1953)

Shakespeare and Nashe Get access Ernest C. York Ernest C. York 1University of Pennsylvania Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume CXCVIII, Issue sep, 1 September 1953, Pages 370–371, https://doi.org/10.1093/nq/CXCVIII.sep.370a Published: 01 September 1953
Applying Systems Modeling Approaches to Building Construction (2016)

Current building modeling environments lack the ability to support coordinated, incremental and systematic description of project requirements, design specifications, and the set of interactions that emerge among them, from different stakeholders, during building design. This paper discusses the prospect of a system-centric modeling framework that integrates a parametric CAD tool with a system modeling application to assess design intent based on construction-specific knowledge. The CAD tool provides strong geometric modeling capabilities, while system modeling allows the description of feature-based design specifications, aligned with construction standards and construction know-how. The ultimate goal of the proposed approach aims for the identification of conflicting interactions between design specifications, from different building material systems and stakeholders, to prevent design errors and on-site rework. The proposed framework will enable collaborative scenarios between Model Based System Engineering and BIM based on parametric, simultaneous, software integration to reduce humanto-data translation errors, improving model consistency among material systems, BIM tools, and project stakeholders.
Raman Spectroscopy as a Potential Tool for Detection of Brucella spp. in Milk (2012)

Detection of Brucella, causing brucellosis, is very challenging, since the applied techniques are mostly time-demanding and not standardized. While the common detection system relies on the cultivation of the bacteria, further classical typing up to the biotype level is mostly based on phenotypic or genotypic characteristics. The results of genotyping do not always fit the existing taxonomy, and misidentifications between genetically closely related genera cannot be avoided. This situation gets even worse, when detection from complex matrices, such as milk, is necessary. For these reasons, the availability of a method that allows early and reliable identification of possible Brucella isolates for both clinical and epidemiological reasons would be extremely useful. We evaluated micro-Raman spectroscopy in combination with chemometric analysis to identify Brucella from agar plates and directly from milk: prior to these studies, the samples were inactivated via formaldehyde treatment to ensure a higher working safety. The single-cell Raman spectra of different Brucella, Escherichia, Ochrobactrum, Pseudomonas, and Yersinia spp. were measured to create two independent databases for detection in media and milk. Identification accuracies of 92% for Brucella from medium and 94% for Brucella from milk were obtained while analyzing the single-cell Raman spectra via support vector machine. Even the identification of the other genera yielded sufficient results, with accuracies of >90%. In summary, micro-Raman spectroscopy is a promising alternative for detecting Brucella. The measurements we performed at the single-cell level thus allow fast identification within a few hours without a demanding process for sample preparation.
Autologous Fat Grafts: a Quantitative and Morphometric Study in Rabbits (1994)

The aim of this study was to assess the fate of autologous fat tissue grafts harvested and processed by five different methods: blunt suction, sharp suction, dissection, treatment, and lavage. Fat was harvested from the subcutaneous tissue of the interscapular region in 25 rabbits and injected into the subcutaneous area of the convex surface of the ear. Harvesting was by either open surgical excision or suction. Where open surgical excision was used, the fragments were cut into smaller pieces with scissors. Suction in the blunt and sharp suction groups was through cannulas with blunt or sharp edged suction holes, respectively. In both suction groups and the dissection group the harvested tissue was injected without further processing. In the treatment group 2 ml of cell 199 culture medium and Earle's basic salt solution were added, and in the lavage group the tissue was washed with Ringer's lactate. Animals were killed at 7 (n = 9), 180 (n = 8), and 360 (n = 8) days. Serial cross sections were taken from each recipient area and the specimens processed for histology. The images from each section were digitised in a computer and, with the assistance of image analysis software, the volume of remaining fat cells was calculated for each recipient area. The percentage volumes of fat cells found in each group at 360 days were: blunt suction 14% sharp suction 35%, dissection 45%, treatment 27%, and lavage 16% (p = 0.003).
Propagation of single-cycle terahertz pulses in random media (2001)

We describe what are to our knowledge the first measurements of the propagation of coherent, single-cycle pulses of terahertz radiation in a scattering medium. By measuring the transmission as a function of the length L of the medium, we extract the scattering mean free path l(s)(omega) over a broad bandwidth. We observe variations in l(s) ranging over nearly 2 orders of magnitude and covering the entire thin sample regime from L/l(s)<<1 to L/l(s)~10 . We also observe scattering-induced dispersive effects, which can be attributed to the additional path traveled by photons scattered at small angles.
Li-ion storage and gas adsorption properties of porous polyimides (PIs) (2014)

In this work, three polyimides (PIs) are successfully synthesized by the condensation reaction of an aromatic triamine with three difunctional aromatic dianhydrides. These materials show electrochemical lithium ion storage properties as cathodes for lithium-ion batteries. The aromatic dianhydride monomers are found to have significant effects on their performances. In addition, the polymer PI-1 shows narrow micropore size distributions and selective adsorption of CO2 over CH4 and N2. Furthermore, PI-1 exhibits a high Qst value (11.7 kJ mol−1) for H2 adsorption.
Simulation of sparse neural networks on a CNAPS SIMD neurocomputer (1997)

Neuroanatomical aspects of the mammalian cerebral cortex can be modeled by neural networks with a sparse and random connection scheme. This paper presents such sparse network models and appropriate algorithms, data structures and optimization for an efficient parallel simulation on a CNAPS SIMD neurocomputer. Using these methods a considerable speedup in comparison to sequential computation is achieved. INTRODUCTION The complete (or at least regular) interconnection between or inside groups of neurons is characteristic for the vast majority of artificial neural networks. Present general purpose, massively parallel computers including CNAPS and other neurocomputers are especially suited for the implementation of these artificial neural networks, but work much less effective when applied to sparse random networks like those modeling neuroanatomical aspects of the mammalian cerebral cortex. Nevertheless, using special simulation algorithms and data structures including preparatory optimiz...
Wet-Suited SCUBA Diver Performance in 5-25 C Water (1981)

As an assessment of adequacy of current Navy diving guidelines for thermal protection, the performance and physiology of three wet-suited SCUBA divers were measured over a series of 36 dives in water temperatures ranging from 5 C to 25 C. The divers performed cognitive and motor tasks during dives lasting up to 50 min at a depth of 3.35 m; heart rate, respiration rate, and skin temperatures were recorded at 5-min intervals. Results indicated that despite substantial decreases in skin temperatures, diver performance on cognitive tasks was not significantly affected; motor performance was impaired only when water temperature reached 5 C. These results indicate that the standard neoprene wet suit provides adequate protection during dives in shallow water at temperatures as low as 10 C and for exposure times as long as 50 min. (Author)
<title>Application of dynamic gratings to broad spectral band beam steering</title> (1994)

In this paper we consider some of the implications of steering broad spectral band radiation using dynamic gratings. The similarities and differences in dispersion between dynamic gratings formed with electro-optic phase arrays and with microlens arrays are highlighted. Optical design considerations are presented that limit the dispersion in the image. System designs that use refractive, diffractive, and combinations of refractive and diffractive components to partially correct for the dispersion are analyzed.
A Synthetic Peptide Corresponding to the Extracellular Domain of Occludin Perturbs the Tight Junction Permeability Barrier (1997)

Occludin, the putative tight junction integral membrane protein, is an attractive candidate for a protein that forms the actual sealing element of the tight junction. To study the role of occludin in the formation of the tight junction seal, synthetic peptides (OCC1 and OCC2) corresponding to the two putative extracellular domains of occludin were assayed for their ability to alter tight junctions in Xenopus kidney epithelial cell line A6. Transepithelial electrical resistance and paracellular tracer flux measurements indicated that the second extracellular domain peptide (OCC2) reversibly disrupted the transepithelial permeability barrier at concentrations of < 5 microM. Despite the increased paracellular permeability, there were no changes in gross epithelial cell morphology as determined by scanning EM. The OCC2 peptide decreased the amount of occludin present at the tight junction, as assessed by indirect immunofluorescence, as well as decreased total cellular content of occludin, as assessed by Western blot analysis. Pulse-labeling and metabolic chase analysis suggested that this decrease in occludin level could be attributed to an increase in turnover of cellular occludin rather than a decrease in occludin synthesis. The effect on occludin was specific because other tight junction components, ZO-1, ZO-2, cingulin, and the adherens junction protein E-cadherin, were unaltered by OCC2 treatment. Therefore, the peptide corresponding to the second extracellular domain of occludin perturbs the tight junction permeability barrier in a very specific manner. The correlation between a decrease in occludin levels and the perturbation of the tight junction permeability barrier provides evidence for a role of occludin in the formation of the tight junction seal.
Structural Mechanism for Heparin-Binding of the Third Kunitz Domain of Human Tissue Factor Pathway Inhibitor<sup>,</sup> (2001)

Tissue factor pathway inhibitor (TFPI) inhibits the activity of coagulation factor VIIa and Xa through its K1 and K2 domain, respectively, and the inhibitory activity is enhanced by heparin. The function of the K3 domain of TFPI has not been established, but the domain probably harbors a heparin binding site (HBS-2). We determined the three-dimensional solution structure of the TFPI K3 domain (Glu182-Gly242) by heteronuclear multidimensional NMR. The results showed that the molecule is composed of one antiparallel beta-sheet and one alpha-helix, and in overall structure is very similar to the K2 domain, with the rms deviation of 1.55 A for the 58 defined C(alpha) positions. However, the surface electrostatic properties of both domains are different each other. The lack of inhibitory activity of the K3 domain is explained by the absence of electrostatic interaction with factor Xa over a large surface area. A titration experiment with size-fractionated heparin showed that a heparin binding site was located in the vicinity of the alpha-helix. In this region, a positively charged cluster is formed by Lys213, Lys232, and Lys240, and the negatively charged sulfate groups of heparin bind there. The enhancement of inhibitory activity by heparin probably was not due to a conformational change to TFPI itself. It is likely that heparin simply increases the local concentration of TFPI on the cell surface and stabilizes the initial complex that forms.
A Block-Based Hough Transform Mapping for Text Line Detection in Handwritten Documents (2006)

In this paper, we present a new text line detection method for unconstrained handwritten documents. The proposed technique is based on a strategy that consists of three distinct steps. The first step includes preprocessing for image enhancement, connected component extraction and average character height estimation. In the second step, a block-based Hough transform is used for the detection of potential text lines while a third step is used to correct possible false alarms. The performance of the proposed methodology is based on a consistent and concrete evaluation technique that relies on the comparison between the text line detection result and the corresponding ground truth annotation.
Sustained Remission of Multicentric Castleman Disease in Children Treated with Tocilizumab, an Anti-Interleukin-6 Receptor Antibody (2012)

Multicentric Castleman Disease (MCD) is an idiopathic lymphoproliferative disorder, reported exceptionally in children and generally believed to be an autoinflammatory disease resulting in an increase of interleukin-6 secretion. Previous studies in adult patients suggested a beneficial role of the anti-interleukin-6 receptor antibody tocilizumab on the clinical and biologic disease manifestations of MCD. Here, we describe the efficacy and safety of tocilizumab in two children with MCD, which was diagnosed on the basis of clinical and histologic findings. In both cases, tocilizumab was administered intravenously at a dose of 8 mg/kg every 2 weeks. The tocilizumab treatment alleviated fever and restored growth rate in both patients. The patients' hypergammaglobulinemia, high C-reactive protein, and high erythrocyte sedimentation rates normalized simultaneously. Nevertheless, splenomegaly persisted in the first patient, and a secondary hepatic node appeared in the second patient. The side effects, essentially sustained thrombocytopenia, were mild in both cases. For the first patient, following an initial 10-month period, the interval between infusions was increased. This patient benefited from sustained remission for a period of 3 years. Tocilizumab was effective and safe in these two children with MCD.
Learning from Experiences of Non-Personhood: A Self-Study of Teacher Educator Identities (2015)

This self-study examines how our non-personhood experiences (NPHEs) contributed to our teacher educator identity process. We took up exploration of these experiences, which were very painful for us, not as entrée into victimhood but because we wanted to learn something about how, in the face of such experiences, we could engage with these troubling interactions in order to renew our commitment to our work as teacher educators in the university. During the analysis, we considered our stories on four overlapping dimensions: (1) our selves in our own story, (2) others in the story, (3) colleagues not in the story, and (4) non-colleagues and others not in the story. A framework for looking at our NPHEs allows teacher educators to attend to students' needs while simultaneously reasserting their own teacher educator identities in more honest and vulnerable ways. Analyzing NPHEs has the potential to help teacher educators engage and invite students to recognize teacher educators' personhood and thereby better position them to recognize the personhood of their future students.
Amination Reactions (2008)

Abstract The sections in this article are Introduction Amination of Alcohols Aliphatic Alcohols Amination over Metal Catalysts (Dehydrogenation Route) Amination over Solid Acid Catalysts (Dehydration Route) Amino Alcohols, Polyalcohols Amination of Phenols Amination of Carbonyl Compounds (Reductive Alkylation) Reaction Mechanism Catalysts, Reaction Conditions Selective Synthesis of Primary, Secondary, or Tertiary Amines Amination with Bifunctional Amines or Carbonyl Compounds Heterocyclic Ring Formation Stereoselectivity Amination of Carboxylic Acids and Esters Amination of Alkenes and Alkynes (Hydroamination) Amination of Ethers Amination of Halogen Compounds Amination of Haloalkanes Amination of Haloaryls Amination of Hydrocarbons Amination of Carbon Monoxide and Carbon Dioxide
Providing middleware support for the control and co-ordination of telecom mashups (2007)

The emerging Web 2.0 marketplace presents an important opportunity for Telecom operators to sell their own capabilities and content as services. Operators have a wealth of content associated with their network as well as core network enablers, e.g. call control, presence and messaging, which could serve as potential new revenue streams in a Web 2.0 world. Moreover, with the looming threat from Internet companies, there is an increasing need for operators to make both core and value-added functions reusable and mashable. To this end, operators are gradually embracing the IP Multimedia Subsystem (IMS) and looking at developing next-generation of SIP-based applications that can be mashed up in innovative ways. However, to do so, IMS/SIP-based services need to be empowered with the necessary co-ordination capabilities required in a mashup environment. This, in turn, implies protocol-level control to be rendered to the mashup developer - an issue that has not been sufficiently addressed by the community. We highlight the need for middleware support in facilitating the co-ordination of Telecom mashups, and describe an architecture that provides the necessary runtime control and mediation in an IMS-based operator network.
Deep Learning Face Attributes in the Wild (2014)

Predicting face attributes in the wild is challenging due to complex face variations. We propose a novel deep learning framework for attribute prediction in the wild. It cascades two CNNs, LNet and ANet, which are fine-tuned jointly with attribute tags, but pre-trained differently. LNet is pre-trained by massive general object categories for face localization, while ANet is pre-trained by massive face identities for attribute prediction. This framework not only outperforms the state-of-the-art with a large margin, but also reveals valuable facts on learning face representation. (1) It shows how the performances of face localization (LNet) and attribute prediction (ANet) can be improved by different pre-training strategies. (2) It reveals that although the filters of LNet are fine-tuned only with image-level attribute tags, their response maps over entire images have strong indication of face locations. This fact enables training LNet for face localization with only image-level annotations, but without face bounding boxes or landmarks, which are required by all attribute recognition works. (3) It also demonstrates that the high-level hidden neurons of ANet automatically discover semantic concepts after pre-training with massive face identities, and such concepts are significantly enriched after fine-tuning with attribute tags. Each attribute can be well explained with a sparse linear combination of these concepts.