gebhart/patrepeval huggingface dataset:
Detection of nitrogen dioxide using a room temperatureoperation mid-infrared InSb light emitting diode (1998)

The authors report trace gas detection of nitrogen dioxide (NO2) using a room temperature operation InSb LED and an infrared absorption technique. A gas growth characteristic has been obtained for an 11 cm long gas cell containing a light pipe for light collection and transmission. The results show that detection of NO2 at a concentration level of 10 ppm can be achieved in this sensor design.
A Monograph of the Beetles Associated with Stored Products (1945)

A Monograph of the Beetles Associated with Stored Products Get access A Monograph of the Beetles Associated with Stored Products, by Hinton H. E.. Vol. I, pp. viii+443, 1945. Published by the British Museum (Natural History). Price, two pounds ten shillings. Annals of the Entomological Society of America, Volume 38, Issue 4, 1 December 1945, Page 602, https://doi.org/10.1093/aesa/38.4.602 Published: 01 December 1945
Transient species involved in catalytic dioxygen/peroxide activation by hemoproteins: possible involvement of protonated Compound I species (2005)

Interaction of hemoproteins with peroxide leads in several cases to transient formation of ferric peroxo, ferric hydroperoxo, and "high-valent", formally Fev, oxo or hydroxo Compound species. Here, density functional calculations on ferric peroxo, ferric hydroperoxo, Compound and protonated Compound heme active site models are reported. The theoretical results, including calculated isotropic Fermi contact couplings and anisotropic spin dipole couplings, are found to generally correlate well with experimental EPR/ENDOR data. Hydrogen bonding and solvation affect the ferric-peroxo/ferrous-superoxo electromerism. The transition between the two electromers appears smooth, but neither hydrogen bonding to up to two water molecules, nor solvation appear able to dramatically alter the redox state of the superoxo ligand or of the iron. The presence of almost one full unpaired electron on the iron and of one full unpaired electron on the dioxygenic ligand in the "ferric-peroxo" state suggests a possible description of non-protonated "ferric-peroxo" as {ferric-superoxo+porphyrin radical}. Emerging from the DFT data is the possibility that a protonated Compound has already been detected in ENDOR experiments on cytochrome P450. The general feasibility of a protonated Compound in P450 monooxygenases is probed in light of these findings. To encompass the multiple mechanisms available in P450 for substrate oxidation, we define "mechanistic promiscuity" as the feature allowing an enzyme to perform the same reaction, with the same product, using more than one mechanism.
영어 학습자 네러티브와 스탠스를 통한 아이덴터티 (2019)

본 연구는 ESL 프로그램을 수강하는 학습자를 대상으로 네러티브에서 나타난 스탠스 표지어를 통해 학습자의 아이덴터티가 어떻게 설정되는 지를 조사하고자한다. 미국 남부의 한 주립대학교 ESL 학습자 9명이 본 연구에 참여하였다. 참여자들의 영어실력은 중-하에 속했고 문화적 배경은 서로 달랐다. 참여자는 개인 경험을 한 차례 이야기한 후, 바로 옆에 위치한 교실로 가서 동일한 내용을 다른 청중에게 한 번 더 이야기했다. 이들의 네러티브는 녹화되었고 전사되었다. 스탠스 표지어를 중심으로 오리엔테이션, 인식양상, 정의적 태도, 일반화 표지어로 나누어 분석하였다. 그 결과, 두 차례의 네러티브는 일반화 스탠스를 제외하고는 커다란 차이는 없었다. 이는 학습자가 일반화 스탠스 표지어를 통해 다른 문화에서 자신의 정체성을 명시적으로 전달하고 있음을 시사하고 있다. 두 번째, 학습자는 평가를 통한 가치부여 단어를 사용하여 자신의 정의적 스탠스를 표현하였다. 세 번째, 인지적 표지어는 가능성과 확실성을 나타내는 표현을 중심으로 그 사용량은 비슷했다. 마지막으로, 학습자는 인지 표지어와 소망을 나타내는 정의적 표지어 표현을 제한적으로 사용하였다. 따라서 학습자는 정체성 표현을 위한 다양한 스탠스 표지어를 학습할 필요가 있다. 향후에는 다양한 수준의 학습자를 대상으로 스탠스와 정체성과의 관계에 대하여 연구를 확대할 것으로 예상된다.
Observations on Induced Thiamine (Vitamin B1) Deficiency in Man (1990)

(1990). Observations on Induced Thiamine (Vitamin B1) Deficiency in Man. Journal of Nutritional Medicine: Vol. 1, No. 1, pp. 73-74.
Fabrication of 0.25 μm surface acoustic wave devices by ion beam proximity printing (1991)

The electrodes of surface acoustic wave (SAW) devices cannot be represented in a stencil mask as cantilevered beams because the high aspect ratio makes them unstable. Therefore a complementary exposure technique has been developed. The mask pattern is formed by segmenting the electrodes into equal length open and closed areas. The wafer is then exposed twice with an offset equal to the segment length, thus forming a continuous electrode image. This approach has two advantages: (1) the high process latitude of ion beam proximity printing (IBPP) is preserved since, in contrast to the grid-support approach, no areas are doubly exposed; and (2) only precision translation is required to register the exposures, preserving the single level nature of SAW patterns. Linewidth is shown to change by less than ±15% for ±20% changes in exposure at a 0.25 μm nominal linewidth.
CaMKII Binding to GluN2B Is Differentially Affected by Macromolecular Crowding Reagents (2014)

Binding of the Ca2+/calmodulin(CaM)-dependent protein kinase II (CaMKII) to the NMDA-type glutamate receptor (NMDAR) subunit GluN2B controls long-term potentiation (LTP), a form of synaptic plasticity thought to underlie learning and memory. Regulation of this interaction is well-studied biochemically, but not under conditions that mimic the macromolecular crowding found within cells. Notably, previous molecular crowding experiments with lysozyme indicated an effect on the CaMKII holoenzyme conformation. Here, we found that the effect of molecular crowding on Ca2+/CaM-induced CaMKII binding to immobilized GluN2B in vitro depended on the specific crowding reagent. While binding was reduced by lysozyme, it was enhanced by BSA. The ATP content in the BSA preparation caused CaMKII autophosphorylation at T286 during the binding reaction; however, enhanced binding was also observed when autophosphorylation was blocked. Importantly, the positive regulation by nucleotide and BSA (as well as other macromolecular crowding reagents) did not alleviate the requirement for CaMKII stimulation to induce GluN2B binding. The differential effect of lysozyme (14 kDa) and BSA (66 kDa) was not due to size difference, as both dextran-10 and dextran-70 enhanced binding. By contrast, crowding with immunoglobulin G (IgG) reduced binding. Notably, lysozyme and IgG but not BSA directly bound to Ca2+/CaM in an overlay assay, suggesting a competition of lysozyme and IgG with the Ca2+/CaM-stimulus that induces CaMKII/GluN2B binding. However, lysozyme negatively regulated binding even when it was instead induced by CaMKII T286 phosphorylation. Alternative modes of competition would be with CaMKII or GluN2B, and the negative effects of lysozyme and IgG indeed also correlated with specific or non-specific binding to the immobilized GluN2B. Thus, the effect of any specific crowding reagent can differ, depending on its additional direct effects on CaMKII/GluN2B binding. However, the results of this study also indicate that, in principle, macromolecular crowding enhances CaMKII binding to GluN2B.
A 70-ns word-wide 1-Mbit ROM with on-chip error-correction circuits (1985)

A 1-Mb ROM has been developed, organized as either 64K/spl times/16 or 128K/spl times/8 in a pin-selectable option. Multiplexing the address inputs and the data outputs onto the same pins makes it possible to fit into a 28-pin package and to perform straightforward interfacing with some popular 16-bit microprocessors. The process technology is a 1.5-/spl mu/m twin-well double-level-metal CMOS on a grounded p-type substrate. The device uses some dynamic circuitry during the start of the active cycle, but automatically takes itself back into the static precharge state-except for the latched outputs. Typical access time is 70 ns. New high-speed error detection and correction circuits were developed which work in about 10 ns. Because all 16 outputs are not driven at once, but half are delayed by about 15 ns through a process-tracking delay circuit, the on-chip error correction is finished before the process-tracking delay circuit is through, and error correction costs no further access penalty. These error correction circuits enhance both yield and reliability.
纳米金辅助的激光转染方法研究 (2009)

The irradiation of cells combined with the immunoconjugate of gold nanoparticles by the short pulse laser can make the plasma membrane be transiently permeabilized, which can be used to transfer exogenous molecules into the cells. We explore this technique as a novel gene transfection method for floating cells. Three different floating cells exposed to the laser are selectively transfected with fluorescein isothiocyanatedextran, antibody, and green fluorescent protein (GFP) coding plasmids, and the viability of cells are determined by propidium iodide. For fluorescein isothiocyanate-dextran, the best transfection efficiency of 65% is obtained; for the antibody, it is 74%; whereas for the green fluorescent protein coding plasmids, a very small transfection efficiency is gained. If the transfection efficiency is improved, gold nanoparticles will be very useful as mediator for gene transfection in living cells.
Invariant image recognition by Zernike moments (1990)

The problem of rotation-, scale-, and translation-invariant recognition of images is discussed. A set of rotation-invariant features are introduced. They are the magnitudes of a set of orthogonal complex moments of the image known as Zernike moments. Scale and translation invariance are obtained by first normalizing the image with respect to these parameters using its regular geometrical moments. A systematic reconstruction-based method for deciding the highest-order Zernike moments required in a classification problem is developed. The quality of the reconstructed image is examined through its comparison to the original one. The orthogonality property of the Zernike moments, which simplifies the process of image reconstruction, make the suggest feature selection approach practical. Features of each order can also be weighted according to their contribution to the reconstruction process. The superiority of Zernike moment features over regular moments and moment invariants was experimentally verified.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Acoustoelectric Interactions in Thin-Film Semiconductors Induced by Two Contra-Directed Surface Acoustic Waves (1985)

The nonlinear acoustoelectric interactions due to two con- tra-directed surface acoustic waves (SAW) for device geometries, consist- ing of semiconductor thin films, are analyzed in a unified and coherent manner. Main features of the nonlinear interactions to be addressed are biphased characteristics, signal enhancement, symmetry, and surface conditions. The geometries discussed are those utilizing the transverse, the normal and the tangential components of electric fields induced by two contra-directed SAW's through piezoelectric coupling. Experimental results are included. ARIOUS TYPES of acoustoelectric signal processors have been reported ( l)-(21). However, most of the structures discussed so far are with semiconductors of infinite thickness; i.e., larger than several Debye lengths. In this paper the nonlinear acoustoelectric interactions due to two contra- directed surface acoustic waves (SAW) for device geometries, particularly consisting of semiconductor thin films, are analyzed in a unified and coherent manner. Main features of the nonlinear interactions to be addressed are biphased characteristics, signal enhancement, symmetry, and surface conditions. Geometries to be discussed are those utilizing the transverse, the normal and the tangential components of electric fields induced by two contra-directed SAW's through piezoelectric coupling. Assuming that the surface acoustic waves are propagating in the z-direction, substrate surface is in the xz plane and the surface normal is in the y direction. Then, the transverse, normal, and tangential correspond to the directions of x, y, and z, respectively. In the transverse-mode operation, the nonlinear signal generation due to two contra-directed SAW's at both the sum and difference frequencies are zero in the absence of dc biasing due to the symmetry of the device
A vital role for Angptl3 in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro (2015)

Angptl3 is a novel factor involved in the PAN-induced podocyte loss by affecting detachment and apoptosis in vitro. This study helps to deepen the understanding of the mechanisms of podocyte loss and lays the foundation for developing a new successful therapy for podocyte injury via lower expression of Angptl3.
Relationship Between β-Cell Mass and Fasting Blood Glucose Concentration in Humans (2006)

36.5 5.3 kg/m 2 ). We only included people with type 2 diabetes who were not taking insulin or glucose-lowering oral medications, both of which would have influenced the measured blood glucose concentrations and the relationship of these with -cell volume. The relationship between fractional -cell volume and fasting blood glucose concentration was analyzed by nonlinear regression analysis to establish the best monoexponential fit of the relationship between the fasting blood glucose (dependent variable) and the -cell volume (independent variable); y span exp(k X) plateau and the point of inflection of the hyperbole. ANOVA was used to test for the effect of -cell volume on fasting blood glucose. RESULTS— There was a significant relationship between the -cell volume and fasting blood glucose concentration, with a point of inflection at x 1.1 0.1%. This relationship is curvilinear (Fig. 1) so that -cell deficiency beyond 1.1% is associated with a steep increase in blood glucose with each further decrement in -cell mass.
Improved Re-Entry Prediction Method Using the Last-Minute Motion of Re-Entering Objects (2014)

Japan Aerospace Exploration Agency (JAXA) has been carrying out the re-entry prediction of the debris for more than 30 years. Formerly, we had used only Two Line Elements (TLE) by U.S. Space Surveillance Network (SSN) for the re-entry prediction. After developing the Kamisaibara Space Guard Center (KSGC) which has a phased-array radar and is owned by Japan Space Forum, we have been performing the orbit determination and prediction by radar observation data in parallel. In this paper, focusing on re-entry objects in a low altitude with large fluctuations, we will report on and discuss about the orbit determination method using radar observation data of only a single arc and only two TLEs just before the re-entry. As a result, we confirmed an improvement in the prediction accuracy.
Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors. (2000)

After the transplantation of unmodified marrow from human leukocyte antigen-matched unrelated donors receiving cyclosporine (CSP) and methotrexate (MTX), the incidence of acute graft-versus-host disease (GVHD) is greater than 75%. Tacrolimus is a macrolide compound that, in previous preclinical and clinical studies, was effective in combination with MTX for the prevention of acute GVHD. Between March 1995 and September 1996, 180 patients were randomized in a phase 3, open-label, multicenter study to determine whether tacrolimus combined with a short course of MTX (n = 90), more than CSP and a short course of MTX (n = 90), would reduce the incidence of acute GVHD after marrow transplantation from unrelated donors. There was a significant trend toward decreased severity of acute GVHD across all grades (P =.005). Based on the Kaplan-Meier estimate, the probability of grade II-IV acute GVHD in the tacrolimus group (56%) was significantly lower than in the CSP group (74%; P =.0002). Use of glucocorticoids for the management of GVHD was significantly lower with tacrolimus than with CSP (65% vs 81%, respectively; P =. 019). The number of patients requiring dialysis in the first 100 days was similar (tacrolimus, 9; CSP, 8). Overall and relapse-free survival rates for the tacrolimus and CSP arms at 2 years was 54% versus 50% (P =.46) and 47% versus 42% (P =.58), respectively. The combination of tacrolimus and MTX after unrelated donor marrow transplantation significantly decreased the risk for acute GVHD than did the combination of CSP and MTX, with no significant increase in toxicity, infections, or leukemia relapse.
Exploring Efficiency of Ring Oscillator-Based Temperature Sensor Networks on FPGAs (Abstract Only) (2015)

Due to technology advances and complexity of designs, thermal issue is a bottleneck in electronics designs. Various dynamic thermal management techniques have been proposed to address this issue. To effectively apply thermal management techniques, providing an accurate thermal map of chips is highly required. For this goal, a network of temperature sensors ought to be provided. There are various implementations for temperature sensors and network of sensors on Field Programmable Gate Arrays (FPGAs). This work defines and formulates four metrics and criteria, in terms of area, thermal, and power overheads and thermal map accuracy for exploring and evaluating efficiency of different implementations of Ring Oscillator-based Temperature Sensor (ROTS) networks on FPGAs and reports the comparison results for 12 networks with various sensor configurations. According to our metrics and experiments, the sensor that it is composed of NOT gates with open latches and RNS ring counter has lower thermal and power overheads compared to other configurations. Moreover, in this work, a new ROTS is presented that occupies 25% less resources than the most compact temperature sensor. Also, it provides 1.72 times higher sensitivity than the best sensitive ROTS design.
Intestinal Epithelium in Inflammatory Bowel Disease (2014)

The intestinal epithelium has a strategic position as a protective physical barrier to luminal microbiota and actively contributes to the mucosal immune system. This barrier is mainly formed by a monolayer of specialized intestinal epithelial cells (IECs) that are crucial in maintaining intestinal homeostasis. Therefore, dysregulation within the epithelial layer can increase intestinal permeability, lead to abnormalities in interactions between IECs and immune cells in underlying lamina propria, and disturb the intestinal immune homeostasis, all of which are linked to the clinical disease course of inflammatory bowel disease (IBD). Understanding the role of the intestinal epithelium in IBD pathogenesis might contribute to an improved knowledge of the inflammatory processes and the identification of potential therapeutic targets.
Handbook of Electromagnetic Materials: Monolithic and Composite Versions and Their Applications (1995)

Introduction Dielectric Materials Electrical Insulating Materials Composite Dielectric Materials Complex Permittivity of Dielectric Composite Materials Composite Dielectric Materials with a Discrete Conducting Phase Conductor-Loaded Polymeric and Ceramic Materials Conducting Polymeric Materials Conductive Materials Semiconducting Materials Superconducting Materials Ferroelectric Materials Peizoelectric Composite Materials Ferromagnetic Materials Ferrite Materials Solid Electrolytic Materials Electrooptic Materials Electrochromic Materials Electronic Packing Materials Static Control Materials Electromagnetic Shielding Materials Electromagnetic Wave Absorbing Materials Electromagnetic Smart Materials Electrorheological Materials Electromagnetic Chiral Materials Electromagnetic Phantom Materials
Overexpression of the c-src protein does not induce transformation of NIH 3T3 cells. (1984)

NIH 3T3 mouse cells were transfected with plasmids that induce efficient expression of either (i) the Rous sarcoma virus v-src gene, (ii) the chicken c-src gene, or (iii) a recombinant gene combining the 5' portion of c-src with the 3' end of v-src. Focus formation in tissue culture and formation of large colonies in soft agar did not occur in cells transfected with c-src. Cells transfected with c-src expression plasmids did not form foci but were isolated using a coselectable biological marker. They display morphological and substrate-independent growth characteristics intermediate between those of normal and v-src-transformed mouse cells, and lysates from these cells have enhanced in vitro tyrosine kinase activity. Transfection with the c-src-v-src recombinant induced focus formation with an efficiency similar to that obtained with a v-src expression plasmid. These results imply that v-src-induced transformation does not result just from overexpression of an essentially normal cellular protein but, at least in part, depends on the mutations distinguishing the cellular and viral proteins.
Load forecasting via suboptimal seasonal autoregressive models and iteratively reweighted least squares estimation (1993)

Suboptimal least squares or iteratively reweighted least-squares (IRWLS) procedures for estimating the parameters of a seasonal multiplicative autoregressive (AR) model encountered during power system load forecasting are proposed. The method involves using an interactive computer environment to estimate the parameters of a seasonal multiplicative AR process. The method comprises five major computational steps. The first determines the order of the seasonal multiplicative AR process, and the second uses the least squares or the IRWLS to estimate the optimal nonseasonal AR model parameters. In the third step one obtains the intermediate series by back forecast, which is followed by using the least squares or the IRWLS to estimate the optimal seasonal AR parameters. The final step uses the estimated parameters to forecast future load. The method is applied to predict the Nova Scotia Power Corporation's 168 lead time hourly load. The results obtained are documented and compared with results based on the Box and Jenkins method.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Analgesic efficacy of diclofenac in combination with morphine and paracetamol after mastectomy and immediate breast reconstruction (2005)

The addition of NSAID to paracetamol and opioid-PCA reduced opioid consumption and improved pain relief during the first 20 h at rest but was not convincingly effective during mobilization. Post-operative blood loss was higher with diclofenac.
Detection of mutations in mitochondrial DNA by droplet digital PCR (2016)

Mutations in mitochondrial DNA (mtDNA) may result in various pathological processes. Detection of mutant mtDNAs is a problem for diagnostic practice that is complicated by heteroplasmy - a phenomenon of the inferring presence of at least two allelic variants of the mitochondrial genome. Also, the level of heteroplasmy largely determines the profile and severity of clinical manifestations. Here we discuss detection of mutations in heteroplasmic mtDNA using up-to-date methods that have not yet been introduced as routine clinical assays. These methods can be used for detecting mutations in mtDNA to verify diagnosis of "mitochondrial disease", studying dynamics of mutant mtDNA in body tissues of patients, as well as investigating structural features of mtDNAs. Original data on allele-specific discrimination of m.11778G>A mutation by droplet digital PCR are presented, which demonstrate an opportunity for simultaneous detection and quantitative assessment of mutations in mtDNAs.
CMOS integrated infrared sensor (2002)

CMOS integrated microsensors (CIMS) technology has been developed that combines bulk micromachining, pyroelectric materials and a commercial CMOS process to provide an integrated infrared sensor. This sensor system is based on a new sol-gel derived thin film fabricated on thin silicon micro electromechanical structure. The sensor has a peak responsivity of 2.33 V/W and a thermal time constant of 300 ms.