gebhart/patrepeval huggingface dataset:
Personalizing the capture of public experiences (1999)

In this paper, we describe our work on developing a system to support the personalization of a captured public experience. Specifically, we are interested in providing students with the ability to personalize the capture of the lecture experiences as part of the Classroom 2000 project. We discuss the issues and challenges involved in designing a system that performs live integration of personal streams of information with multiple other streams of information made available to it through an environment designed to capture public information.
Rapid detection of human hemoglobin Quong Sze by polymerase chain reaction. (1993)

Human hemoglobin Quong Size is a nondeletional defect involving codon 125 of the alpha 2-globin gene. The molecular defect is a T to C mutation, therefore, a new MspI site (CCGG) is created. Using a pair of flanking DNA primers and polymerase chain reaction, a DNA fragment of 339 basepairs (bp) was amplified. After MspI restriction and gel electrophoresis, the mutation could be clearly identified by the presence of two fragments, 108 and 123 bp. This method is rapid and simple and will be very useful in the genetic counseling of Southeast Asians, including the Chinese, in which nondeletional alpha-thalassemia defects are common.
Intra-Arterial Delivery Is Not Superior to Intravenous Delivery of Autologous Bone Marrow Mononuclear Cells in Acute Ischemic Stroke (2013)

At low and high doses of MNCs, we found that IV or IA achieves similar structural and functional outcomes after stroke.
Volumetric Hand Reconstructions for Non-verbal Communication in Shared Virtual Environments (2010)

Enhancing desk-based computer environments with virtual reality technology requires natural interaction support, in particular hand tracking and visualization. In shared virtual environments hand tracking does not only support interaction with the virtual environment, but also provides a channel for non-verbal communication. This paper presents a tabletop user interface and its integration into a three-dimensional teleconferencing system. Dense volume reconstructions of hands based on a probabilistic Shape from Silhouette algorithm are applied for tracking and visualization. The interface integration employs the derived probabilistic hand reconstructions to interactively generate mesh models characterized as isosurfaces of probabilistic volume data. It will be shown, that meshes resulting from probabilistic volume reconstructions thereby exhibit superior detail in comparison to mesh models generated from non-probabilistic comparative approaches which represent the current state of the art.
Haemagglutination by parvovirus B19 (1992)

Human parvovirus B19 is a member of the autonomous parvoviridae but in contrast to other members of the genus has not been shown to agglutinate red blood cells. We now report that the virus agglutinates red cells of primate origin, though with plasma-derived virus this activity is masked by the presence of an IgM-like inhibitor. This observation is consistent with the presence on the erythroid precursor target cell of a specific receptor for parvovirus B19.
Efficacy Versus Systemic Effects of Six Topical Steroids in the Treatment of Atopic Dermatitis of Childhood (1984)

Six groups of children suffering from widespread atopic dermatitis were treated once daily with six topical steroids of different potency. Systemic effects were measured by the morning estimation of plasma cortisol. A clear relationship was demonstrated between clinical efficacy of the steroid treatment and degree of reduced adrenal function. This study demonstrated that a rapid and marked therapeutic effect can be obtained with potent topical steroids applied once daily without occlusion, but in children is accompanied by a fall in plasma cortisol.
A Model for Turbulent Combustion Noise (2009)

We validate a spectral model for the fluctuating heat release rate of turbulent premixed flames which can be used in the source term of the acoustical wave equation to calculate the noise emission of turbulent combustion devices. The model is based on an assumed Eulerian model spectrum of progress variable, on a turbulent combustion model and on a space time mapping which allows to transform the spatial spectrum into a temporal spectrum needed for the acoustical wave equation. The details and the overall performance of the model were validated experimentally on premixed swirling jet flames using optical and acoustical measurement techniques, which are explained in the paper. The comparison is very good suggesting that the model can be applied in the engineering practice which is demonstrated on two examples.
Purification of β-Core Fragment from Pregnancy Urine and Demonstration That Its Carbohydrate Moieties Differ from Those of Native Human Chorionic Gonadotropin-β (1988)

Pregnancy urine contains large quantities of hCG, free beta-subunit, free alpha-subunit, and a population of fragments of beta-subunit known as beta-core. This beta-core population, which can account for as much as 70% of the total beta-immunoreactivity in pregnancy urine, is of interest as both a normal metabolite of pregnancy and a potential marker for malignancy. We have purified the beta-core fragment from pregnancy urine (P-core) and have characterized it with respect to size and carbohydrate composition. P-Core was purified by chromatography on Sephadex G-100, Concanavalin A (Con A)-Sepharose, DEAE-Sephacel, and Sephadex G-75 (superfine). The purified P-core has an apparent mol wt of 17,500 and 17,000, as determined by gel filtration on Sephadex G-75 (superfine) and sodium dodecyl sulfate-polyacrylamide gel electrophoresis under nonreducing conditions, respectively. The sialic acid content of P-core was assayed chemically and was less than 0.07 mumol sialic acid/mumole P-core. For comparison to P-core, we have prepared a trypsin fragment of beta-subunit that retains the beta-core immunological determinant recognized by SB6 antiserum and lacks the carboxy-terminal immunological determinant. We have designated this beta-core molecule as T-core (tryptic fragment of beta-subunit) to distinguish it from the beta-core molecule that we have purified from pregnancy urine (i.e. P-core). Most of the P-core and T-core molecules bind to Con A (84% and 86%, respectively). The Con A-bound material was used for subsequent characterizations. Neither P-core nor T-core binds to DEAE using conditions under which intact hCG beta binds to DEAE. A variety of agarose-bound lectins were used to further investigate the carbohydrate nature of the Con A-bound P-core and T-core molecules. The lectin binding data indicate that the antennae on P-core do not contain appreciable sialic acid or galactose, in contrast to the antennae on T-core, which contain both. We conclude that P-core, the naturally occurring beta-core fragment in pregnancy, has been processed to a form in which nearly all of the sialic acid and galactose residues are removed, but the Con A-binding site (consisting of the core sugars) and most of the core fucose are retained.
Gene expression in cancer: the application of microarrays (2003)

Genome-wide monitoring of gene expression using DNA microarrays represents one of the latest breakthroughs in experimental molecular biology and provides unprecedented opportunity to explore the biological processes underlying human diseases by providing a comprehensive survey of a cell's transcriptional landscape. In the cancer field, this revolutionary technology allows the simultaneous assessment of the transcription of tens of thousands of genes, and of their relative expression between normal cells and malignant cells. As microarray analysis emerges from its infancy, there is widespread hope that microarrays will significantly impact on our ability to explore the genetic changes associated with cancer etiology and development, and ultimately lead to the discovery of new biomarkers for disease diagnosis and prognosis prediction, and of new therapeutic tools. This review provides an overview of microarray technology, specifically in the context of cancer research and describes some of its recent applications to the study of cancer. In addition, the challenges of translating microarray findings into molecular cancer diagnosis and prognosis tools, with the potential of altering clinical practice through individualized cancer care and ultimately of contributing to the battle against cancer, are discussed.
Clinical effectiveness of hemoglobin spray (Granulox<sup>®</sup>) as adjunctive therapy in the treatment of chronic diabetic foot ulcers (2016)

Standard wound care plus hemoglobin spray results in improvements in wound closure, wound size reduction, pain, slough, and exudate levels compared to control patients for chronic diabetic foot ulcer treatment.
Microstrip patch antenna with defected ground structure &#x00026; defected microstrip structure (2008)

In this paper we propose the antenna geometry to design a very compact microstrip patch antenna using thin dielectric substrate having low dielectric constant. This antenna provide better efficiency, better band-width without any enhancement in the weight, volume or cost. HFSS high frequency simulator is employed to analyze the proposed antenna and simulated results on return loss, the E-and H-plane radiation pattern is presented. The antenna parameter in frequency domain analysis has been investigated to show its capability as an effective radiating element. Due to low-profile structure it used in the wireless application.
A formal approach to fault tree synthesis for the analysis of distributed fault tolerant systems (2005)

Designing cost-sensitive real-time control systems for safety-critical applications requires a careful analysis of both performance versus cost aspects and fault coverage of fault tolerant solutions. This further complicates the difficult task of deploying the embedded software that implements the control algorithms on a possibly distributed execution platform (for instance in automotive applications). In this paper, we present a novel technique for constructing a fault tree that models how component faults may lead to system failure. The fault tree enables us to use existing commercial analysis tools to assess a number of dependability metrics of the system. Our approach is centered on a model of computation, Fault Tolerant Data Flow (FTDF), that enables the integration of formal verification techniques. This new analysis capability is added to an existing design framework, also based on FTDF, that enables a synthesis-based, correct-by-construction, design methodology for the deployment of real-time feedback control systems in safety critical applications.
Food Discoloration, Reddening of White Onion Bulb Purees (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFood Discoloration, Reddening of White Onion Bulb PureesM. A. Joslyn and R. G. PetersonCite this: J. Agric. Food Chem. 1958, 6, 10, 754–765Publication Date (Print):October 1, 1958Publication History Published online1 May 2002Published inissue 1 October 1958https://doi.org/10.1021/jf60092a006RIGHTS & PERMISSIONSArticle Views103Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
3D Bioprinting Strategies for the Regeneration of Functional Tubular Tissues and Organs (2020)

It is difficult to fabricate tubular-shaped tissues and organs (e.g., trachea, blood vessel, and esophagus tissue) with traditional biofabrication techniques (e.g., electrospinning, cell-sheet engineering, and mold-casting) because these have complicated multiple processes. In addition, the tubular-shaped tissues and organs have their own design with target-specific mechanical and biological properties. Therefore, the customized geometrical and physiological environment is required as one of the most critical factors for functional tissue regeneration. 3D bioprinting technology has been receiving attention for the fabrication of patient-tailored and complex-shaped free-form architecture with high reproducibility and versatility. Printable biocomposite inks that can facilitate to build tissue constructs with polymeric frameworks and biochemical microenvironmental cues are also being actively developed for the reconstruction of functional tissue. In this review, we delineated the state-of-the-art of 3D bioprinting techniques specifically for tubular tissue and organ regeneration. In addition, this review described biocomposite inks, such as natural and synthetic polymers. Several described engineering approaches using 3D bioprinting techniques and biocomposite inks may offer beneficial characteristics for the physiological mimicry of human tubular tissues and organs.
SEARCH STATE EQUIVALENCE FOR REDUNDANCY IDENTIFICATION AND TEST GENERATION (2005)

We present new extensions to the EST' algoritlm, which accelerates combinational circuit Redundancy Identification and Automatic Test Pattern Generation (ATPG) algorithms, in particular SOCRATES. EST detects equivalent search states, which are saved. for all faults during ATPG. The search space is reduced by using learned Search State equiualences to detect previously-encountered search states (possibly from prior faults) and to make internal node assignments. We present two extensions to EST. The first ensures that each portion of the ATPG search space is explored only once. The second applies headline objectives in parallel, rather than serially. For the 1965 ISCAS combinational benchmarks, EST accelerates S 0 CRATES by 6.53 times, when all faults are targeted, and by 5.51 times, when used with random pattern generation, f,iult simulation and fault dropping. This acceleration was achieved with minimal memory overhead.
An Analysis of the Gap between PWB Technology and Chip I/O Interconnect Technology, and a New Wafer-Level Batch Packaging Concept (1999)

A dramatic reduction in the size and cost of electronic devices has taken place in the past decades. The functionality of electronic devices continues to increase leading to higher I/O counts. This trend of reduced size and higher I/O count requires the examination of the compatibility between the integrated circuits (IC) and the Printed Wiring Board (PWB) interconnection technologies. Wafer level batch packaging addresses the packaging and interconnections needs of IC by building flexible embedded leads in a compliant overcoat that will extend the on-chip I/O pad to the point where it can be directly attached to the system Printed Wiring Board (PWB) without using underfill. As such, the entire assembly is an extension of IC fabrication and on-chip interconnections. In this paper, the IC and PWB interconnection needs are analyzed and compared. First, an analysis of the I/O needs of ICs from the NTRS roadmap are compared to the microvia PWB technologies from NEMI, ITRI and JPCA roadmaps. Various IC-to-PWB interconnection technologies are examined to study their use and limitations in meeting the I/O needs of future IC under wafer level batch packaging concept. Second, the products from specific PWB manufacturers are reviewed in terms of roadmap needs. Third, the impact of IC and PWB interconnection designs on the electrical performance issues such as I/O current density, cross talk, off-chip speed are qualitatively described. This analysis indicates that the opportunities for miniaturization lie on the chip-side rather than on the PWB side.
On the complexity of scheduling conditional real-time code (2001)

Many real-time embedded systems involve a collection of independently executing event-driven code blocks, having hard real-time constraints. Portions of such codes when triggered by external events require to be executed within a given deadline from the triggering time. The feasibility analysis problem for such a real-time system asks whether it is possible to schedule all such blocks of code so that all the associated deadlines are met even in the worst case triggering sequence. Each such conditional real-time code block can be naturally represented by a directed acyclic graph whose vertices correspond to portions of code having a straight-line flowof control and are associated with execution requirements and deadlines relative to their triggering times, and the edges represent conditional branches. Till now, no complexity results were known for the feasibility analysis problem in this model, and all existing algorithms in the real-time systems literature have an exponential complexity. In this paper we show that this problem is NP-hard under both dynamic and static priorities in the preemptive uniprocessor case, even for a set of only two task graphs. For dynamic-priority feasibility analysis we give a pseudo-polynomial time exact algorithm and a fully polynomial-time approximation scheme for approximate feasibility testing. For the special case where all the execution requirements of the vertices are identical, we present a polynomial time exact algorithm. For static-priority feasibility analysis, we introduce a new sufficient condition and give a pseudo-polynomial time algorithm for checking it. This algorithm gives tighter results for feasibility analysis compared to those known so far.
Analysis of Energy Harvesting Positive Displacement Motor (2007)

Drilling operations in deep and ultradeep water are increasing around the world. The development of these substantial prospects provides many challenges and requires the integration of knowledge with prudent designs at different stages of the well development. Also, more wells are drilled in rotary steerable mode and other instrumented bottom-hole assemblies. All of these tools need power, which is stored in batteries. Because the downhole power supply is limited for these tools, an alternate mode of energy supply is needed so that these tools can remain downhole for long hours. This paper examines a new energy source extraction method using the hydraulic energy obtained from the circulated drilling fluid when downhole motors are used.
Violet laser diodes as light sources for cytometry (2001)

Background Violet laser diodes have recently become commercially available. These devices emit 5–25 mW in the range of 395–415 nm, and are available in systems that incorporate the diodes with collimating optics and regulated power supplies in housings incorporating thermoelectric coolers, which are necessary to maintain stable output. Such systems now cost several thousand dollars, but are expected to drop substantially in price. Materials and Methods A 4-mW, 397-nm violet diode system was used in a laboratory-built flow cytometer to excite fluorescence of DAPI and Hoechst dyes in permeabilized and intact cells. Forward and orthogonal light scattering were also measured. Results DNA content histograms with good precision (G0/G1 coefficient of variation 1.7%) were obtained with DAPI staining; precision was lower using Hoechst 33342. Hoechst 34580, with an excitation maximum nearer 400 nm, yielded the highest fluorescence intensity, but appeared to decompose after a short time in solution. Scatter signals exhibited relatively broad distributions. Conclusions Violet laser diodes are relatively inexpensive, compact, efficient, and quiet light sources for DNA fluorescence measurement using DAPI and Hoechst dyes; they can also excite several other fluorescent probes. Cytometry 44:133–136, 2001. © 2001 Wiley-Liss, Inc.
A clustering algorithm for hierarchical structures (1977)

article Free Access Share on A clustering algorithm for hierarchical structuresACM Transactions on Database SystemsVolume 2Issue 1March 1977 pp 27–44https://doi.org/10.1145/320521.320531Published:01 March 1977Publication History 61citation787DownloadsMetricsTotal Citations61Total Downloads787Last 12 Months21Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Interaction of human liver cytochromes P450 in vitro with LY307640, a gastric proton pump inhibitor (1996)

The interactions in vitro of LY307640 with the cytochromes P450 (P450s) were studied using human liver microsomes, specific inhibitors of the P450s, and cDNA expressed enzymes. The kinetics of formation of the two major oxidative metabolites, desmethyl LY307640 and LY307640 sulfone, were determined using two human liver microsomal samples. The kinetic data indicated that high and low affinity sites were present for the production of both metabolites of LY307640. The Km(apparent) and Vmax(apparent) for desmethyl LY307640 formation by microsomes from human liver E (HL-E) for the high affinity site were 18.8 +/- 4.4 microM and 402 +/- 52 pmol product/min/mg protein. The high affinity site Km(apparent) and Vmax(apparent) for LY307640 sulfone formation by microsomes from HL-E were 4.4 +/- 2.1 microM and 81.8 +/- 18 pmol product/min/mg protein. The rates of desmethyl LY307640 and LY307640 sulfone formation by the high affinity site were determined using 14 human liver microsomal samples characterized for P450 marker catalytic activities and immunoquantified levels of the P450s. Rates of formation of desmethyl LY307640 significantly correlated with the immunoquantified levels of CYP 2C19 and the ability of the microsomes to 4'-hydroxylate S-mephenytoin. LY307640 sulfone formation significantly correlated with the immunoquantified levels of CYP 3A and the ability of the microsomes to 1'-hydroxylate midazolam. Inhibition studies and use of expressed cytochrome P450 systems confirmed the correlation data demonstrating that CYP 2C19 catalyzed the formation of desmethyl LY307640 and CYP 3A and catalyzed LY307640 sulfone formation. Further, LY307640 competitively inhibited S-mephenytoin 4'-hydroxylation and midazolam 1'-hydroxylation as did the structurally related compound, omeprazole. For the inhibition of S-mephenytoin 4'-hydroxylation and midazolam 1'-hydroxylation, LY307640 had higher Ki(apparent) values than that of omeprazole. These studies demonstrate that the high affinity enzymes which catalyze the formation of the desmethyl and sulfone metabolites of LY307640 are, respectively, CYP 2C19 and CYP 3A. In addition, the inhibition data suggest that LY307640 has less potential to inhibit the metabolism of CYP 2C19 substrates compared to omeprazole, and that LY307640 and omeprazole have a similarly low potential to inhibit the metabolism of CYP 3A substrates.
Reductive Cleavage of Chiral Acetals Using New Aluminum Catalyst (1993)

The reaction of acetals derived from (-)-(2R,4R)-2,4-pentanediol and ketones in the presence of a catalytic amount of aluminum pentafluorophenoxide produces reductively cleaved products with high diastereoselectivity. The reaction is a new method for diastereoselective cleavage of acetals: an intramolecular Meerwein-Ponndorf-Verley reductive and Oppenauer oxidative reaction on an acetal template.