gebhart/patrepeval huggingface dataset:
First Clinical Report of a New Biodegradable Membrane for Use in Urological Surgery (1991)

Following preliminary in vitro and in vivo experiments a new collagen Vicryl mesh has been devised. The membrane has been extensively tested in the laboratory and has been found to resist the passage of urine. It holds sutures well and has been shown on an experimental animal to be biodegradable. The membrane has now been applied in human subjects. It has been particularly efficacious in renal surgery and as a means of sealing a bladder after it has been opened. With respect to the ureter the sealing effect is excellent, to the extent of having produced a urinoma. The membrane has been found to be easily applied in vesicovaginal fistulae but difficulties have been experienced in the presence of infection. It is also an ideal membrane for repair of a urethrovaginal fistula--an area where natural tissues are less easily available. This is the first recorded use of this new biodegradable membrane in the human subject.
Search User Interfaces (2009)

The truly world-wide reach of the Web has brought with it a new realisation of the enormous importance of usability and user interface design. In the last ten years, much has become understood about what works in search interfaces from a usability perspective, and what does not. Researchers and practitioners have developed a wide range of innovative interface ideas, but only the most broadly acceptable make their way into major web search engines. This book summarizes these developments, presenting the state of the art of search interface design, both in academic research and in deployment in commercial systems. Many books describe the algorithms behind search engines and information retrieval systems, but the unique focus of this book is specifically on the user interface. It will be welcomed by industry professionals who design systems that use search interfaces as well as graduate students and academic researchers who investigate information systems.
An economic and system analysis of the automated hardwood lumber processing system (ALPS). (1992)

The concept of an automated lumber processing system using lasers for cutting wood parts is briefly reviewed. Economic analysis of the concept using an interactive computer model is described. Results of the analysis in terms of net present value and internal rate of return are presented under a range of assumptions regarding lumber mix, input costs, lumber yield, and factors that affect the speed of laser cutting.
Photolithographic patterning of phosphor screens by electrophoretic deposition for field emission display application (1998)

The patterning of phosphor screens was carried out using a lithographic technique and electrophoretic deposition of phosphor particles for high-resolution field emission display applications. The electrophoretic deposition and photolithography steps were established. Patterned phosphor screens were fabricated by controlling process parameters such as electrophoretic deposition rate in combination with a well-controlled photoresist process in order to achieve proper pixel size with clear boundaries.
The Effect of Cisplatin and Fluorouracil on Xenografted Human Squamous Cell Carcinoma of the Head and Neck (1988)

In combined modality treatment, cisplatin and fluorouracil are considered to act synergistically. The assumption is based on results in murine leukemias and has not hitherto been tested on human squamous cell carcinoma. In the present study, cisplatin and fluorouracil, used singly and in combination, were tested on two human squamous cell carcinomas of the head and neck, xenografted to nude mice. Cisplatin (7.5 mg/kg) was given as a single-dose intraperitoneal injection and fluorouracil as repeated intraperitoneal injections every eight hours for four days to a total dose of 200 mg/kg. The toxicity of the cisplatin and fluorouracil combination was lower (27%) than that of fluorouracil alone (50%). Both drugs gave a dose-dependent inhibition of tumor volume growth. Using gained growth delay as endpoint, cisplatin and fluorouracil therapy exhibited a synergistic effect on both tumor lines.
Feasibility study of a control system based on PLC and EPICS for the ESTHER combustion gas injection (2015)

The ESTHER laboratory will simulate spacecraft atmosphere re-entry conditions by generating a shock wave through the deflagration of a hydrogen, oxygen and helium gas mixture. The gas injection sequence into the combustion chamber must be precisely and safely controlled in order to prescribe the initial pressure in the two-stage shock tube and to avoid accidental detonations in any part of the system. In this work, a prototype control system setup using a Siemens PLC in an EPICS and CSS software environment is presented. An example application was developed, where a simple control sequence implemented on the PLC was remotely monitored and controlled by an operator interface. This setup was able to meet the control system requirements and the prototype served as the starting point for the development of the complete ESTHER gas injection controller.
Valency conversion in the type 1 fimbrial adhesin of <i>Escherichia coli</i> (2001)

FimH protein is a lectin-like adhesive subunit of type 1, or mannose-sensitive, fimbriae that are found on the surface of most Escherichia coli strains. All naturally occurring FimH variants demonstrate a conserved mannotriose-specific (i.e. multivalent) binding. Here, we demonstrate that replacement of residues 185-279 within the FimH pilin domain with a corresponding segment of the type 1C fimbrial adhesin FocH leads to a loss of the multivalent mannotriose-specific binding property accompanied by the acquisition of a distinct monomannose-specific (i.e. monovalent) binding capability. Bacteria expressing the monovalent hybrid adhesins were capable of binding strongly to uroepithelial tissue culture cells and guinea pig erythrocytes. They could not, however, agglutinate yeast or bind human buccal cells -- functions readily accomplished by the E. coli-expressing mannotriose-specific FimH variants. Based on the relative potency of inhibiting compounds of different structures, the receptor binding site within monovalent FimH-FocH adhesin has an extended structure with an overall configuration similar to that within the multivalent FimH of natural origin. The monomannose-only specific phenotype could also be invoked by a single point mutation, E89K, located within the lectin domain of FimH, but distant from the receptor binding site. The structural alterations influence the receptor-binding valency of the FimH adhesin via distal effects on the combining pocket, obviously by affecting the FimH quaternary structure.
microRNA 223 Is Upregulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting <i>PARP1</i> (2013)

miR-223 is significantly upregulated during the Barrett's esophagus-dysplasia-esophageal adenocarcinoma sequence. Although high miR-223 levels might contribute to an aggressive phenotype, our results also suggest that patients with esophageal adenocarcinoma with high miR-223 levels might benefit from treatment with DNA-damaging agents.
On the role of the amplitude of the fricative noise in the perception of place of articulation in voiceless fricative consonants (1988)

The current study explores the role of the amplitude of the fricative noise in the perception of place of articulation in voiceless fricative consonants. The amplitude of the fricative noise in naturally produced fricative-vowel utterances was varied relative to the vowel and potential changes in perceptual responses were investigated. The amplitude of the fricative noise for [s] and [s] was reduced such that the amplitude of the noise relative to the vowel was similar to [f] and [O], and, conversely, the amplitude of the fricative noise of [f] and [O] was increased such that the amplitude of the noise relative to the vowel was similar to [s] and [s]. The fricative noise was presented to listeners in both its vowel context and in isolation. Results indicated that, when the spectral properties of the fricative noise and formant transitions are compatible, the perceptual effects of the amplitude manipulation of the amplitude of the noise had a small effect on the overall identification of place of articulation, and when effects emerged, they varied across the different fricative stimuli. Moreover, although decreasing the amplitude of [s] and [s] resulted in an increase in [f] and [O] responses, increasing the amplitude of [f] and [O] did not result in an increase in [s] and [s] responses. Implications of these findings for phonetic feature theories are considered.
Neural Network Training Using Genetic Algorithms (1996)

Artificial neural networks genetic algorithms mathematical foundations of genetic algorithms genetic algorithms for neural network training case studies comparison of genetic algorithms with back-propagation.
Highly Efficient and Scalable Compound Decomposition of Two-Electron Integral Tensor and Its Application in Coupled Cluster Calculations (2017)

The representation and storage of two-electron integral tensors are vital in large-scale applications of accurate electronic structure methods. Low-rank representation and efficient storage strategy of integral tensors can significantly reduce the numerical overhead and consequently time-to-solution of these methods. In this work, by combining pivoted incomplete Cholesky decomposition (CD) with a follow-up truncated singular vector decomposition (SVD), we develop a decomposition strategy to approximately represent the two-electron integral tensor in terms of low-rank vectors. A systematic benchmark test on a series of 1-D, 2-D, and 3-D carbon-hydrogen systems demonstrates high efficiency and scalability of the compound two-step decomposition of the two-electron integral tensor in our implementation. For the size of the atomic basis set, N<sub>b</sub>, ranging from ∼100 up to ∼2,000, the observed numerical scaling of our implementation shows [Formula: see text] versus [Formula: see text] cost of performing single CD on the two-electron integral tensor in most of the other implementations. More importantly, this decomposition strategy can significantly reduce the storage requirement of the atomic orbital (AO) two-electron integral tensor from [Formula: see text] to [Formula: see text] with moderate decomposition thresholds. The accuracy tests have been performed using ground- and excited-state formulations of coupled cluster formalism employing single and double excitations (CCSD) on several benchmark systems including the C<sub>60</sub> molecule described by nearly 1,400 basis functions. The results show that the decomposition thresholds can be generally set to 10<sup>-4</sup> to 10<sup>-3</sup> to give acceptable compromise between efficiency and accuracy.
Verbal case frame acquisition from a bilingual corpus (1994)

This paper describes acquisition of English surface case frames from a corpus, based on a gradual knowledge acquisition approach. To acquire and unambiguously accumulate precise knowledge, the process is divided into three steps which are assigned to the most appropriate processor: either a human or a computer. The data is prepared by human workers and the knowledge is acquired and accumulated by a leaning program. By using this method, inconsistent human judgement is minimized. The acquired case frames basically duplicate human work, but are more precise and intelligible.
The variations of sensitivity to gamma radiation in different strains of Mycobacterium phlei (2009)

Strains of Mycobacterium phlei differ in sensitivity to γ-radiation. The acid-fast strain PA was 2.4 times more sensitive than the non-acid-fast strains PN and its morphological mutant PN-bb. A higher sensitivity of the acid-fast strain to γ-radiation is in agreement with its sensitivity to UV-radiation and chemical mutagens, described before in the literature. The new mutant PN-bb, which was isolated after treatment of the strain PN with 60Co γ-radiation and ethyl methanesulfonate, shows an unusual morphological character of the colonies and was more resistant to γ-radiation at higher doses, indicating that a certain fraction of the cells had a lower sensitivity to γ-radiation.
The compressive behavior of bone as a two-phase porous structure (1977)

Compression tests of human and bovine trabecular bone specimens with and without marrow in situ were conducted at strain rates of from 0.001 to 10.0 per second. A porous platen above the specimens allowed the escape of marrow during testing. The presence of marrow increased the strength, modulus, and energy absorption of specimens only at the highest strain rate of 10.0 per second. This enhancement of material properties at the highest strain rate was due primarily to the restricted viscous flow of marrow through the platen rather than the flow through the pores of the trabecular bone. In specimens without marrow, the strength was proportional to the square of the apparent density and the modulus was proportional to the cube of the apparent density. Both strength and modulus were approximately proportional to the strain rate raised to the 0.06 power. These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
Hydrogen-deuterium exchange studies utilizing a thermospray mass spectrometer interface (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrogen-deuterium exchange studies utilizing a thermospray mass spectrometer interfaceMarshall M. SiegelCite this: Anal. Chem. 1988, 60, 19, 2090–2095Publication Date (Print):October 1, 1988Publication History Published online1 May 2002Published inissue 1 October 1988https://pubs.acs.org/doi/10.1021/ac00170a021https://doi.org/10.1021/ac00170a021research-articleACS PublicationsRequest reuse permissionsArticle Views124Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Hybrid antibody‐mediated lysis of virus‐infected cells (1987)

Previously, cytotoxic T lymphocytes (CTL) had only been focused by hybrid antibodies to normal, cell-surface proteins and haptenated surface structures. In this report, we extend the application of this technology to mediate lysing of virus-infected cells by nonspecific CTL. Heteroconjugated antibodies between the anti-T cell antigen receptor antibody, F23.1, and monoclonal antibodies against either the hemagglutinin or nucleoprotein of the influenza virus PR/8 were constructed. We show in the present report that these bispecific constructs can target virus-infected cells for lysis according to the specificity of the virus-protein reactive monoclonal antibodies. Furthermore, even a virus protein that is only expressed in small quantities on the cell surface, such as nucleoprotein, can be exploited as target structure for heteroconjugated antibodies. These studies show that hybrid antibodies can focus a CTL response on virus-infected cells which might in the future be used to mount an immune response in situations without sufficient normal cellular defense.
High power light-emitting diode junction temperature determination from current-voltage characteristics (2008)

Optical and electrical characteristics of power light-emitting diodes (LEDs) are strongly dependent on the diode junction temperature. However, direct junction temperature determination is not possible and alternative methods must be developed. Current-voltage characteristics of commercial high power LEDs have been measured at six different temperatures ranging between 295 and 400 K. Modeling these characteristics, including variation in the bandgap with temperature, revealed a linear temperature dependence of the forward voltage if the drive current is chosen within a rather limited current range. Theoretically, the voltage intercept can be deduced from the bulk semiconductor bandgap. However, accurate junction temperature determination is only possible if at least two calibration measurements at a particular drive current are performed. The method described in this paper can be applied to calculate the thermal resistance from the junction to any other reference point for any particular LED configuration.
Disengagement of Visual Attention in Infancy is Associated with Emerging Autism in Toddlerhood (2013)

Infants who develop autism or other developmental concerns show atypicality in the development of visual attention skills from the first year of life.
Clinical Evaluation of a Commercial Photorefractor (1987)

The Visiscreen 100 is a system designed to detect ocular anomalies photographically. Photorefractions obtained in 63 consecutive 3-month-old to 8-year-old patients were compared in a masked fashion with results obtained by conventional techniques, including cycloplegic refraction. In 87% of the 57 patients with analyzable photographs, photorefractive and examination results correlated for the detection of constant tropias. The photorefractor detected all ocular media opacities. In 77% of the cases, its refraction was within 2.5 diopters or 33% of the cycloplegic spherical equivalent. In detecting abnormal ocular status, the Visiscreen had a 91% sensitivity and a 74% specificity. The overall agreement rate in distinguishing abnormal from normal status was 84%. Most errors were related to inaccuracies in fixation and positioning, rather than the optical principles utilized. This device offers a rapid technique for the detection of factors predisposing preverbal children to amblyopia.
A BIST scheme based on resistance match for current-mode R-2R ladder Digital-to-Analog Converter (2011)

This paper presents a Built-in Self-Test (BIST) scheme and its implementation for a current-mode R-2R ladder Digital-to-Analog Converter (DAC). The technique is based on the resistance match of the R-2R ladder in DAC. With the extra Design for Testability (DFT) circuits, test constant current follows into two resistance-matched branches, and the voltage drops on two branches of the resistor ladder change the voltage values at the inputs of the operational amplifier, which works as a comparator in the test mode. The output of the operational amplifier is employed for fault detection through a window comparator, which creates a pass/fail signature signal. The circuit-level simulation and experimental results of the BIST system for a 8-bit DAC in standard CMOS 0.18-µm technology are presented to demonstrate the feasibility of the proposed BIST scheme with fault coverage of 96% and area overhead of approximately 6%.
Modeling and Design of Ferroelectric MOSFETs (2011)

A drain-current model has been developed for ferroelectric metal-oxide-semiconductor field-effect transistors by coupling Pao-Sah double integral with the nonlinear Landau description of the field and polarization of ferroelectric insulators. The resultant solution for surface potential ψ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">s</sub> versus gate voltage V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g</sub> consists of double hysteresis loops sensitive to the ferroelectric-insulator thickness. With a proper choice of the ferroelectric-film thickness, the hysteresis shape can be tailored for operating voltages below 0.5 V, e.g., at V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> = 0.25 V, with a drain-current slope steeper than the reciprocal of 60 mV/dec beyond the threshold voltage.
Asymmetric synthesis and metalation of a binaphthylcyclopentadiene, a C2-symmetric chiral cyclopentadiene (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAsymmetric synthesis and metalation of a binaphthylcyclopentadiene, a C2-symmetric chiral cyclopentadieneSteven L. Colletti and Ronald L. HaltermanCite this: Organometallics 1991, 10, 10, 3438–3448Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://pubs.acs.org/doi/10.1021/om00056a012https://doi.org/10.1021/om00056a012research-articleACS PublicationsRequest reuse permissionsArticle Views1108Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Performance Analysis on Utilizing Directional Antenna in High-Density WLAN (2007)

In this paper, we present a performance study of applying directional antenna to infrastructure-based wireless LAN networks. We focus on high-density (HD) deployment, in which multiple cells are operated on the same channel due to limited non-overlapped channels, and thus network capacity is limited mainly by co-channel interference. Network throughput and fairness index are studied for performance evaluation. Based on the simulation results, we provide insights on how directional antenna should be implemented in a HD-WLAN and how performance scales with network and antenna configurations.