gebhart/patrepeval huggingface dataset:
Distributed Embedded Smart Cameras for Surveillance Applications (2006)

Recent advances in computing, communication, and sensor technology are pushing the development of many new applications. This trend is especially evident in pervasive computing, sensor networks, and embedded systems. Smart cameras, one example of this innovation, are equipped with a high-performance onboard computing and communication infrastructure, combining video sensing, processing, and communications in a single embedded device. By providing access to many views through cooperation among individual cameras, networks of embedded cameras can potentially support more complex and challenging applications - including smart rooms, surveillance, tracking, and motion analysis - than a single camera. We designed our smart camera as a fully embedded system, focusing on power consumption, QoS management, and limited resources. The camera is a scalable, embedded, high-performance, multiprocessor platform consisting of a network processor and a variable number of digital signal processors (DSPs). Using the implemented software framework, our embedded cameras offer system-level services such as dynamic load distribution and task reconfiguration. In addition, we combined several smart cameras to form a distributed embedded surveillance system that supports cooperation and communication among cameras.
Knockdown of TSP50 inhibits cell proliferation and induces apoptosis in P19 cells (2010)

Earlier studies identified testes-specific protease 50 (TSP50), which encodes a threonine protease, and showed that it was abnormally reactivated in many breast cancer biopsies. Further, it was shown to be negatively regulated by the p53 gene. However, little is known about the biological function of TSP50. In this study, we applied RNA interference to knockdown TSP50 gene expression in P19 murine embryonal carcinoma stem cells and tested whether this modulated the cell phenotype. The results showed that downregulation of TSP50 expression not only reduced cell proliferation, colony formation, and migration but also induced cell apoptosis. Further investigation revealed that knockdown of TSP50 resulted in greater sensitivity to doxorubicin-induced apoptosis and that activation of caspase-3 was involved in this process.
Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma (1997)

A lack of p16INK4 expression in NSCLC was observed more frequently in squamous cell carcinoma than in adenocarcinoma, and also was found to be closely related to prognosis, especially in patients with early stage squamous cell carcinoma.
Multi-Point Probing on 65nm Silicon Technology using Static IREM-based Methodology (2005)

Abstract As silicon manufacturing processes move to smaller feature sizes, new silicon fault isolation and debug challenges arise. This paper presents a methodology for silicon fault isolation/debug that allows for simultaneous probing of multiple locations on the die using static infrared emission logic state imaging. Recent tool enhancements leading to more efficient fault isolation and debug are reviewed. Cases are presented from debug of 65nm products showing how this methodology was used to achieve very low throughput times on a variety of complex new failure mechanisms.
A simple method for the fabrication of nanomotors based on a gold nanosheet decorated with CoPt nanoparticles (2015)

In this communication we present an extremely rapid, simple and template-free method for the electrochemical fabrication of CoPt/gold nanosheet motors (NSMs) <italic>via</italic> a three-step applied potential process.
A Deep Learning-Based Model for the Automated Assessment of the Activity of a Single Worker (2020)

Nowadays, it is necessary to verify the accuracy of servicing work, undertaken by new employees, within a manufacturing company. A gap in the research has been observed in effective methods to automatically evaluate the work of a newly employed worker. The main purpose of the study is to build a new, deep learning model, in order to automatically assess the activity of the single worker. The proposed approach integrates the methods known as CNN, CNN + SVM, CNN + R-CNN, four new algorithms and a piece of work from a selected company, using this as an own-created dataset, in order to create a solution enabling assessment of the activity of single workers. Data were collected from an operational manufacturing cell without any guided or scripted work. The results reveal that the model developed is able to accurately detect the correctness of the work process. The model's accuracy mostly exceeds current state-of-the-art methods for detecting work activities in manufacturing. The proposed two-stage approach, firstly, assigning the appropriate graphic instruction to a given employee's activity using CNN and then using R-CNN to isolate the object from the reference frames, yields 94.01% and 73.15% accuracy of identification, respectively.
Analgesic studies on total alkaloids and alcohol extracts of <i>Eclipta alba</i> (Linn.) Hassk. (2004)

A variety of analgesics are used for the treatment of acute and chronic pain in different disease states. A narcotic or a non-narcotic analgesic that does not cause respiratory depression and addiction is needed. In Ayurveda a large number of indigenous drugs have been mentioned possessing analgesic properties (e.g. Guggul, Erand, Rasna, Bhringaraj, Methika, Palandu and Prasikayavani). The present experimental research work was undertaken to determine the analgesic activity of the total ethanol extract of Eclipta alba, and also the isolated alkaloids of Eclipta alba in albino mice by using standard experimental models such as the tail clip method, the tail flick method and the acetic acid induced writhing response. The results from this study show that both the ethanol extract as well as the total alkaloids produce good analgesic activity in all the different models of analgesia used. The total alkaloidal fraction was the most efficacious in all models tested.
Policy-Based IP Address Selection in SCTP Automatic Address Reconfiguration (2011)

SCTP is a reliable transport protocol that supports redundant paths by multiaddressing. Dynamic reconfiguration of IP addresses of an existing association is also supported by an extension called the ADD-IP feature. SCTP tries to use of all available addresses on both end hosts, but among them, there are addresses that should preferably not be used by certain policies or that are known to be unusable beforehand. Trials to use such addresses might cause unexpected degradations of performance or undesired termination of associations by time out. In this study, we propose a new feature by which a user can specify his own address usage policy, per process, according to which a host can determine which address may be used and which should be ignored. If an application program with SCTP is written in the protocol independent programming style, improper addresses are transparently removed so that the application program might use all and only usable addresses.
Metrics for long wavelength asymmetries in inertial confinement fusion implosions on the National Ignition Facility (2014)

We investigate yield degradation due to applied low mode P2 and P4 asymmetries in layered inertial confinement fusion implosions. This study has been performed with a large database of &gt;600 2D simulations. We show that low mode radiation induced drive asymmetries can result in significant deviation between the core hot spot shape and the fuel ρR shape at peak compression. In addition, we show that significant residual kinetic energy at peak compression can be induced by these low mode asymmetries. We have developed a metric, which is a function of the hot spot shape, fuel ρR shape, and residual kinetic energy at peak compression, that is well correlated to yield degradation due to low mode shape perturbations. It is shown that the ρR shape and residual kinetic energy cannot, in general, be recovered by inducing counter asymmetries to make the hot core emission symmetric. In addition, we show that the yield degradation due to low mode asymmetries is well correlated to measurements of time dependent shape throughout the entire implosion, including early time shock symmetry and inflight fuel symmetry.
Methanotrophs and copper (2010)

Methanotrophs, cells that consume methane (CH(4)) as their sole source of carbon and energy, play key roles in the global carbon cycle, including controlling anthropogenic and natural emissions of CH(4), the second-most important greenhouse gas after carbon dioxide. These cells have also been widely used for bioremediation of chlorinated solvents, and help sustain diverse microbial communities as well as higher organisms through the conversion of CH(4) to complex organic compounds (e.g. in deep ocean and subterranean environments with substantial CH(4) fluxes). It has been well-known for over 30 years that copper (Cu) plays a key role in the physiology and activity of methanotrophs, but it is only recently that we have begun to understand how these cells collect Cu, the role Cu plays in CH(4) oxidation by the particulate CH(4) monooxygenase, the effect of Cu on the proteome, and how Cu affects the ability of methanotrophs to oxidize different substrates. Here we summarize the current state of knowledge of the phylogeny, environmental distribution, and potential applications of methanotrophs for regional and global issues, as well as the role of Cu in regulating gene expression and proteome in these cells, its effects on enzymatic and whole-cell activity, and the novel Cu uptake system used by methanotrophs.
Dynamin-Related Protein 1–Mediated Mitochondrial Mitotic Fission Permits Hyperproliferation of Vascular Smooth Muscle Cells and Offers a Novel Therapeutic Target in Pulmonary Hypertension (2012)

Rationale: Pulmonary arterial hypertension (PAH) is a lethal syndrome characterized by pulmonary vascular obstruction caused, in part, by pulmonary artery smooth muscle cell (PASMC) hyperproliferation. Mitochondrial fragmentation and normoxic activation of hypoxia-inducible factor-1α (HIF-1α) have been observed in PAH PASMCs; however, their relationship and relevance to the development of PAH are unknown. Dynamin-related protein-1 (DRP1) is a GTPase that, when activated by kinases that phosphorylate serine 616, causes mitochondrial fission. It is, however, unknown whether mitochondrial fission is a prerequisite for proliferation. Objective: We hypothesize that DRP1 activation is responsible for increased mitochondrial fission in PAH PASMCs and that DRP1 inhibition may slow proliferation and have therapeutic potential. Methods and Results: Experiments were conducted using human control and PAH lungs (n=5) and PASMCs in culture. Parallel experiments were performed in rat lung sections and PASMCs and in rodent PAH models induced by the HIF-1α activator, cobalt, chronic hypoxia, and monocrotaline. HIF-1α activation in human PAH leads to mitochondrial fission by cyclin B1/CDK1–dependent phosphorylation of DRP1 at serine 616. In normal PASMCs, HIF-1α activation by CoCl 2 or desferrioxamine causes DRP1-mediated fission. HIF-1α inhibition reduces DRP1 activation, prevents fission, and reduces PASMC proliferation. Both the DRP1 inhibitor Mdivi-1 and siDRP1 prevent mitotic fission and arrest PAH PASMCs at the G2/M interphase. Mdivi-1 is antiproliferative in human PAH PASMCs and in rodent models. Mdivi-1 improves exercise capacity, right ventricular function, and hemodynamics in experimental PAH. Conclusions: DRP-1–mediated mitotic fission is a cell-cycle checkpoint that can be therapeutically targeted in hyperproliferative disorders such as PAH.
Genomic Sequence and Pre-Clinical Safety Assessment of Bifidobacterium longum CECT 7347, a Probiotic able to Reduce the Toxicity and Inflammatory Potential of Gliadin-Derived Peptides (2013)

Bifidobacteria are common inhabitants of human gut and play a significant role in establishing a well-balanced intestinal microbiota. The strain Bifidobacterium longum CECT 7347 (ES1) has been demonstrated to ameliorate damage caused by gluten in celiac disease (CD), both In vitro and in a murine model. Studies suggest that administering this B. longum strain to supplement the gluten-free diet could provide an additional strategy, thereby improving the health status of patients. Here, we report an in-depth study of this strain, adopting a multidisciplinary strategy to demonstrate its safety according to FAO/WHO criteria for probiotic selection. Whole genome sequencing using a massive sequencing approach on the 454 platforms and annotation showed neither relevant virulence nor potential antibiotic resistance genes. It has been demonstrated that values of lactic acid isomer production, bile salt deconjugation and formation of biogenic amines, considered as specifi c traits to be evaluated according to FAO/ WHO, were very similar to levels previously reported in other Bifidobacteria. It has not shown acquired antibiotic resistance In vitro. Moreover, acute ingestion studies in immunocompetent and immunosuppressed BALB/c mouse models did not cause either mortality or morbidity in any group, and did not lead to signifi cant Bifi dobacterial organ translocation, even in the immunosuppressed group. Altogether, these results confi rm the safety status of the strain B. longum CECT 7347. The safety of strain CECT 7347, together with its previously reported functional role in ameliorating gluten- related damage in CD, would indicate it is a probiotic strain.
Integration of relational databases and record-based legacy systems for populating data warehouses (2003)

The number of data sources that an organization has to deal with continues to be nontrivial. Integrating this data is a growing problem. A great deal of research has been done to solve the general problem. Work on topics like multi-databases, mediators and ontologies has been directed at solving the general data integration problem. While all of this activity has been useful, the general problem of integrating heterogeneous data sources remains only partially solved. This paper looks at the solution of a sub-problem of the general problem where the data sources are restricted to relational databases and record-based legacy systems owned by the same organization. For many organizations, this restriction precisely defines their integration problem. For example, data warehouses typically have a tuple as their storage format, whether they are table- or cube-oriented. The task of defining the tuple requires integrating the organization's existing relational and/or record-based legacy systems. Populating the data warehouse can be accomplished by querying the integrated data sources. Specifically, we provide a mechanism for developing a relational model for the set of data sources, provide a method for generating correct queries over the model, and create an architecture for executing the queries based on the mobile agent paradigm. A prototype of the system has been designed and implemented.
Improvement in Nerve Regeneration through a Decellularized Nerve Graft by Supplementation with Bone Marrow Stromal Cells in Fibrin (2013)

Acellular nerve grafting is often inferior as well as an inadequate alternative to autografting for the repair of long gaps in peripheral nerves. Moreover, the injection method is not perfect. During the injection of cells, the syringe can destroy the acellular nerve structure and the limited accumulation of seed cells. To resolve this problem, we constructed a nerve graft by acellular nerve grafting. Bone marrow-mesenchymal stromal cells (BM-MSCs) were affixed with fibrin glue and injected inside or around the graft, which was then used to repair a 15-mm nerve defect in rats. The acellular nerve graft maintained its structure and composition, and its tensile strength was decreased, as determined by two-photon microscopy and a tensile testing device. In vitro, MSCs embedded in fibrin glue survived and secreted growth factors such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). We repaired 15-mm Sprague-Dawley rat sciatic nerve defects using this nerve graft construction, and MSCs injected around the graft helped improve nerve regeneration and functional recovery of peripheral nerve lesions as determined by functional analysis and histology. Therefore, we conclude that supplying MSCs in fibrin glue around acellular nerves is successful in maintaining the nerve structure and can support nerve regeneration similar to the direct injection of MSCs into the acellular nerve for long nerve defects but may avoid destroying the nerve graft. The technique is simple and is another option for stem cell transplantation.
Web services for information extraction from the Web (2004)

Extracting information from the Web is a complex task with different components which can either be generic or specific to the task, going from downloading a given page, following links, querying a Web-based applications via an HTML form and the HTTP protocol, querying a Web service via the SOAP protocol, etc. Therefore building Web services which proceed to executing an information tasks can not be simply hard coded (i.e. written and compiled once and for all in a given programming language). In order to be able to build flexible information extraction Web Services we need to be able to compose different sub tasks together. We propose a, XML-based language to describe information extraction Web services as the compositions of existing Web services and specific functions. The usefulness the proposed framework is demonstrated by three real world applications. (1) Search engines: we show how to describe a task which queries Google's Web service, retrieves more information on the results by querying their respective HTTP servers, and filters them according to this information. (2) E-commerce sites : an information extraction Web service giving access to an existing HTML-based e-commerce online application such as Amazon is built. (3) Patent extraction: a last example shows how to describe an information extraction Web service which allows to query a Web-based application, extract the set of result links, follow them, and extract the needed information on the result pages. In all three applications the generated description can be easily modified and completed to further respond the user's needs and create value-added Web services.
Inhibition of protein synthesis prevents cell death in sensory and parasympathetic neurons deprived of neurotrophic factor <i>in vitro</i> (1990)

Shortly after neurons begin to innervate their targets in the developing vertebrate nervous system they become dependent on the supply of a neurotrophic factor, such as nerve growth factor (NGF) for survival. Recently, Martin et al. (1988) have shown that inhibiting protein synthesis prevents the death of NGF-deprived sympathetic neurons, suggesting that NGF promotes neuronal survival by suppressing an active cell death program. To determine if other neurotrophic factors may regulate neuronal survival by a similar mechanism we examined the effects of inhibiting protein and RNA synthesis in other populations of embryonic neurons that require different neurotrophic factors, namely: 1) trigeminal mesencephalic neurons, a population of proprioceptive neurons that are supported by brain-derived neurotrophic factor; 2) dorsomedial trigeminal ganglion neurons, a population of cutaneous sensory neurons that are supported by NGF; 3) and ciliary ganglion neurons, a population of parasympathetic neurons that are supported by ciliary neuronotrophic factor. Blocking either protein or RNA synthesis rescued all three populations of neurons from cell death induced by neurotrophic factor deprivation in vitro. Thus, at least three different neurotrophic factors appear to promote survival by a similar mechanism that may involve the suppression of an endogenous cell death program.
A PLLR and multi-stage Staircase Regression framework for speech-based emotion prediction (2017)

Continuous prediction of dimensional emotions (e.g. arousal and valence) has attracted increasing research interest recently. When processing emotional speech signals, phonetic features have been rarely used due to the assumption that phonetic variability is a confounding factor that degrades emotion recognition/prediction performance. In this paper, instead of eliminating phonetic variability, we investigated whether Phone Log-Likelihood Ratio (PLLR) features could be used to index arousal and valence in a pairwise low/high framework. A multi-stage staircase regression (SR) framework which enables fusion at three different stages is also investigated. Results on the RECOLA database show that PLLR outperforms EGEMAPS features for arousal and valence. Interestingly, long-term averaged PLLR proved to be more robust and emotionally informative than local frame-level PLLR, which contains more phoneme-specific information. Within the multistage SR framework, PLLR yielded an 8.2% and 11.6% relative improvement in CCC for arousal and valence respectively, showing great promise for including phonetic features in emotion prediction systems.
Detection of Bovine Herpesvirus Type 1 in Blood from Naturally Infected Cattle by Using a Sensitive PCR That Discriminates between Wild-Type Virus and Virus Lacking Glycoprotein E (1999)

In the present study, we report for the first time on the detection of bovine herpesvirus type 1 (BHV-1) in whole-blood samples derived from naturally infected cattle. Sensitive PCR assays specific for glycoprotein B (gB), gC, and gE of BHV-1 allow the detection of one BHV-1 DNA copy in 10(5) to 10(7) peripheral blood leukocytes (PBLs). The incidence of BHV-1-positive PBLs in naturally infected cattle appears to be quite high (92.2% positive PBLs among all samples tested), although in most cases only between 10(-5) and 10(-7) positive leukocytes were present. The results demonstrate that the viral DNA is detectable not only in the peripheral blood of acutely infected animals but, more importantly, also in the peripheral blood of subclinically infected cattle. The gE-specific PCR described in the report allows discrimination between wild-type (WT) virus-infected and vaccinated animals, which is of importance for control programs that use the recently introduced vaccination strategy with a gE-negative virus. The results further show that doubtful serological results can be verified or falsified and that individual animals can be monitored for the presence or absence of WT BHV-1 or gE-negative virus in cattle herds. The PCR protocols allow the detection of BHV-1 prior to seroconversion or in BHV-1-seronegative cattle. Finally, the results indicate the simultaneous presence of WT and gE-negative vaccine virus in the PBLs of several cattle. Therefore, investigations of viremia in naturally and experimentally infected cattle and on the identification of infected cell types of bovine PBLs can be now performed.
Delta-9-tetrahydrocannabinol interferes with the establishment and the expression of conditioned rejection reactions produced by cyclophosphamide (1999)

Reliable animal models of nausea are necessary to better understand the neurobiology of nausea and to assess treatment effectiveness. We present such a model based on conditioned rejection reactions in rats. Our results demonstrate that delta-9-tetrahydrocannabinol (THC), a treatment reported to reduce chemotherapy-induced nausea in humans, also reduces conditioned rejection reactions in rats. Rats were administered THC or vehicle prior to a pairing of saccharin solution with cyclophosphamide or saline during conditioning and/or prior to test. THC interfered with the establishment of cyclophosphamide-induced conditioned rejection during conditioning and with the expression of conditioned rejection during testing. Our results confirm that the conditioned rejection reaction in the rat is a useful animal model of nausea.