gebhart/patrepeval huggingface dataset:
The Border Remains Closed (1994)

25 June 1982 had been fixed as the date for the renewal of talks between Britain and Spain and the opening of the border between Spain and Gibraltar.
Vision-Based People Detection System for Heavy Machine Applications (2016)

This paper presents a vision-based people detection system for improving safety in heavy machines. We propose a perception system composed of a monocular fisheye camera and a LiDAR. Fisheye cameras have the advantage of a wide field-of-view, but the strong distortions that they create must be handled at the detection stage. Since people detection in fisheye images has not been well studied, we focus on investigating and quantifying the impact that strong radial distortions have on the appearance of people, and we propose approaches for handling this specificity, adapted from state-of-the-art people detection approaches. These adaptive approaches nevertheless have the drawback of high computational cost and complexity. Consequently, we also present a framework for harnessing the LiDAR modality in order to enhance the detection algorithm for different camera positions. A sequential LiDAR-based fusion architecture is used, which addresses directly the problem of reducing false detections and computational cost in an exclusively vision-based system. A heavy machine dataset was built, and different experiments were carried out to evaluate the performance of the system. The results are promising, in terms of both processing speed and performance.
Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma (2010)

Radiotherapy remains the backbone of head and neck cancer therapy but response is sometimes impeded by tumor radioresistance. Identifying predictive biomarkers of radiotherapy response is a crucial step towards personalized therapy. The aim of this study was to explore gene expression data in search of biomarkers predictive of the response to radiotherapy in head and neck squamous cell carcinoma (HNSCC). Microarray analysis was performed on five cell lines with various intrinsic radiosensitivity, selected from a panel of 29 HNSCC cell lines. The bioinformatics approach included Gene Ontology (GO) enrichment profiling and Ingenuity Pathway Analysis (IPA). The GO-analysis detected 16 deregulated categories from which development, receptor activity, and extracellular region represented the largest groups. Fourteen hub genes (CEBPA, CEBPB, CTNNB1, FN1, MYC, MYCN, PLAU, SDC4, SERPINE1, SP1, TAF4B, THBS1, TP53 and VLDLR) were identified from the IPA network analysis. The hub genes in the highest ranked network, (FN1, SERPINE1, THBS1 and VLDLR) were further subjected to qPCR analysis in the complete panel of 29 cell lines. Of these genes, high FN1 expression associated to high intrinsic radiosensitivity (p=0.047). In conclusion, gene ontologies and hub genes of importance for intrinsic radiosensitivity were defined. The overall results suggest that FN1 should be explored as a potential novel biomarker for radioresistance.
Simulation of the dynamic response of radioactive material shipping package - railcar systems during coupling operations (1984)

The basic equations of the computer model CARDS (Cask-Railcar DDynamic Simulator), developed for the U.S. Nuclear Regulatory Commission to simulate the dynamic behavior of radioactive material shipping package - railcar systems, are presented. A companion model, CARRS (Cask Railcar Response Spectrum Generator), that generates system response as frequency response spectra is also presented in terms of its basic equations.
Using machine learning models to predict oxygen saturation following ventilator support adjustment in critically ill children: A single center pilot study (2019)

This single center pilot study using machine learning predictive model resulted in an algorithm with poor accuracy. The comparison of machine learning models showed that bagged complex trees was a promising approach. However, there is a need to improve these models before incorporating them into a clinical decision support systems. One potentially solution for improving predictive model, would be to increase the amount of data available to limit over-fitting that is potentially one of the cause for poor classification performances for 2 of the three class labels.
Optimal implementation of conjunctive queries in relational data bases (1977)

We define the class of conjunctive queries in relational data bases, and the generalized join operator on relations. The generalized join plays an important part in answering conjunctive queries, and it can be implemented using matrix multiplication. It is shown that while answering conjunctive queries is NP complete (general queries are PSPACE complete), one can find an implementation that is within a constant of optimal. The main lemma used to show this is that each conjunctive query has a unique minimal equivalent query (much like minimal finite automata).
Antibiotics delay but do not prevent bacteremia and lung injury in murine sepsis (2004)

In this model of sepsis, antibiotics delay but do not prevent acute lung injury and mortality. Even in the presence of antibiotics, acute lung injury is strongly associated with bacteremia and bacteria within the lungs.
Chiral liquid crystalline polymers: Recent issues and perspectives (1993)

Abstract The syntheses and structures of chiral liquid crystalline polymers (LCPs) are briefly reviewed with emphasis on the established structure‐property correlations. The most recent advances and future trends in their potential applications in optics and electrooptics are also outlined, with particular reference to the ferroelectric, electroclinic, piezoelectric, and nonlinear optical properties of chiral LCPs.
Placebo in Functional Dyspepsia: Symptomatic, Gastrointestinal Motor, and Gastric Sensorial Responses (1999)

In patients with functional dyspepsia, the symptomatic response to placebo is substantial. Some significant changes were also observed in gastric motility: increase in the gastric phase III number as well as in the postprandial antral motility index in those with hypomotility pretreatment. Remarkably, however, clinical improvement seems to occur independently of detectable changes in gastroduodenal motor activity or gastric hypersensitivity to distension.
Interference Management Schemes for the Shared Relay Concept (2010)

Sharing a multiantenna relay among several sectors is a simple and cost-effective way to achieving much of the gains of local interference mitigation in cellular networks. Next generation wireless systems, such as ones based on the Third Generation Partnership Projects Long-Term Evolution Advanced, will employ universal frequency reuse to simplify network deployment. This strategy is anticipated to create significant cell-edge interference in the location of the shared relays, thus rendering advanced interference management strategies a necessity. This paper proposes several interference management strategies for the shared relays ranging from simple channel inversion at the relay, to more sophisticated techniques based on channel inversion in combination with partial and full base station coordination in the downlink and uplink. Given that the relay functionality influences total interference, both amplify-and-forward and decode-and-forward type relays are considered throughout. In this context, channel cancelation techniques are investigated for one-way relaying and also the spectrally efficient two-way relaying protocol. Simulations show that strategies based on two-way shared relaying with bidirectional channel inversion at the relay often perform best in terms of total system throughput while one-way techniques are promising when the relay power is low.
The relationship between meal composition and long-term diet choice1 (2002)

When animals are offered a choice of feeds that are nutritionally complementary, they are able to select a consistent combination of these feeds over long periods of time. Analysis of how such consistent diet choice is achieved, in terms of short-term feeding behavior, may further our knowledge of how animals regulate nutrient intake. Previous work, on meal pattern analysis and on nutrient synchronization, led us to hypothesize that animals may select a consistent diet within a meal. In three experiments cows were offered a choice between high- (H) and low- (L) protein feeds and short-term feeding behavior data were collected using computerized feeders. Feeding behavior was first analyzed in terms of visit characteristics. A greater average daily intake of H, relative to L, was more closely related to the ratio of H visits to L visits than to differences in the intake per visit to feeders supplying H or L. Individual meal criteria were estimated using a mixed-distribution model, and visits were clustered into meals. Cows typically had approximately six meals per day. The observed frequency distribution of meal composition, in terms of the proportion of visits to H feeders, was determined. Subsequently, the observed visits were randomly reclustered into bouts consisting of the same number of visits as were observed in meals, and the frequency distribution of random bout composition was calculated. If frequency distributions of meals and random bouts coincide, then this is evidence that cows do not regulate diet choice within a meal. Comparison of the frequency distributions of meals and random bouts provided no evidence that cows attempted to achieve their long-term average diet composition within a meal. We also investigated whether cows tried to achieve a consistent diet choice within a meal by adjusting their intake per visit, depending on the feed type visited and the proportion of visits to H feeders in a meal. There was no evidence that this occurred. In conclusion, our analyses have shown that cows did not attempt to select within a meal a consistent diet in terms of protein to energy ratio. Indeed, our data and the literature suggest that the timeframe over which the intake of energy and protein is regulated must be greater than a meal in a number of animal species.
Fluorescent nanodiamonds for biological applications (2011)

Biomedical imaging often involves the use of fluorophores, bright optical labels which enable observation of objects which are otherwise invisible. Conventional fluorophores include fluorescein, rhodamine, fluorescent proteins and quantum dots; however, often these are limited by cytotoxicity, pH sensitivities, brightness or photo bleaching/blinking [1]. Colour centres in nanodiamonds have many properties which make them attractive for biological applications including their chemical and physical stability, biocompatibility, easy surface modification and their optical and magnetic spin properties.
Kontoführung, Kontokorrent-Abschluß (1969)

Derjenige, der ein Konto eröffnen will, stellt auf einem vom Kreditinstitut zur Verfügung gestellten Vordruck einen Kontoeröffnungsantrag. In vielen Fällen geht der Eröffnung eine Beratung durch den Schalterbeamten über die Art des einzurichtenden Kontos und die mit der Kontoführung gegebenenfalls verbundenen Kosten voraus.
Women and development : objectives, frameworks, and policy interventions (1989)

The contribution of women to an economy is in principle no different from that of men. But in practice, the problems of valuation, measurement, and policy inference are more complex and the implications for policy may be more controversial and culturally sensitive. This paper finds that the private and social returns are high on investments to improve women's economic productivity - particularly education. Where women recieve less education than men, efforts to redress that imbalance deserve priority. Measures to open women's access to information, technology, productive resources, and credit should be tested far more extensively.
Design of the Power Sense of TMDS (2008)

TMDS is mainly accepted by HDMI and DVI standard as RGB data link of PC monitor or HDTV audio/video link,its rate can be high up to 1.65Gbps.In this paper,the performance character of the TMDS and status of the output signal was described at first.Then the detective circuit of power off status was proposed.At last,the design of the module and simulation results were carried out.
Carbohydrate analysis by modern chromatography and electrophoresis (2002)

Selected Papers. The Solute Modern Liquid Chromatography: Fundamentals, Methodologies and Applications Preparative Liquid Chromatography Field Flow Fractionation Electrophoresis and Electrochromatography: Fundamentals, Methodologies and Applications Gas Chromatography The Detection.
The flying-capacitor SEPIC converter with the balancing circuit (2016)

Abstract The paper presents investigation results of the natural balancing phenomena in the flying-capacitor SEPIC converters. The SEPIC converters topologies can be reconfigured to the flying-capacitor topology. Owing to this modification the advantageous increase of frequency of the current in the chokes and the decrease of semiconductors voltages can be achieved which is shown in this paper. Similarly to other multilevel flying capacitor topologies the adequate voltage sharing of the flying capacitors is an important issue for safe operation of the converter. The paper focuses on the analysis of the flying capacitor voltages balancing in the converter by natural currents as well as by the application of the additional RLC balancing booster. The paper proves that the natural balancing can be achieved by the specific application of the balancing circuit in the flying-capacitor SEPIC topology and proves the specific differences in the balancing process by natural currents of converter and with the usage of the balancing circuit. An operation of the converter with the balancing circuit and the natural balancing ability is studied here.
Effects of Tumor Necrosis Factor-α on the In Vitro Maturation of Tumor-Reactive Effector T Cells (2000)

Culture methods that enhance the anti-tumor reactivity of primed T cells would be important in adoptive immunotherapy of cancer. Using several different syngeneic murine tumor models, the authors evaluated the effects of tumor necrosis factor-alpha (TNF-alpha) exposure on tumor-draining lymph node (TDLN) cells during in vitro activation. Mice were inoculated with weakly immunogenic (i.e., MCA 205, MCA 207 sarcoma) or the poorly immunogenic (i.e., D5 melanoma) tumor cells, and TDLN cells were harvested 9 or 10 days later for activation by an anti-CD3/interleukin-2 culture procedure. Human recombinant TNF-alpha (25 ng/mL) added during the activation culture resulted in a two-fold increase in interferon-gamma release (type 1 response) and a significant reduction of interleukin-10 (type 2 response) after tumor antigen stimulation. In an adoptive transfer model, TNF-alpha-cultured TDLN cells mediated significantly greater regression of established tumor than did TDLN cells cultured in the absence of TNF-alpha in five of five experiments. Neutralization of interleukin-10 monoclonal antibody further augmented the therapeutic efficacy of TNF-alpha-cultured TDLN cells. These studies document the ability of TNF-alpha to selectively promote a type 1 over a type 2 response in a bulk population of tumor-primed T cells during in vitro activation.
Steady-state serum pharmacokinetics of novobiocin and rifampin alone and in combination (1986)

Because of the potential of novobiocin-rifampin for oral therapy of methicillin-resistant Staphylococcus aureus infection, we evaluated the pharmacokinetics of novobiocin and rifampin, alone and in combination, in a randomized, crossover, multiple-dose evaluation (500 mg of novobiocin and 300 mg of rifampin administered orally, twice a day, for 27 doses) in 10 volunteers. The half-lives of novobiocin and rifampin when administered alone were 5.85 +/- 1.20 and 1.46 +/- 0.30 h, respectively; when administered in combination, the half-lives were 2.66 +/- 0.65 and 1.43 +/- 0.29 h, respectively. This difference was significant for novobiocin. The area under the curve also differed significantly for novobiocin when administered in combination. No significant differences were seen in the maximum concentration of drug in serum, the time to maximum concentration of drug in serum, or both for either drug when single and combination therapy groups were compared. A change in clearance of novobiocin rather than a change in absorption is the more likely explanation for these findings. The mechanism remains to be elucidated. Nevertheless, the trough serum concentrations of both novobiocin and rifampin were in excess of the MIC for 90% of strains tested of methicillin-resistant S. aureus, even when coadministered.
REALIZATION OF GENERALIZED SOFT-AND-HARD BOUNDARY (2006)

The classical soft-and-hard surface boundary conditions have previously been generalized to the form a E = 0 and b H = 0 where a and b are two complex vectors tangential to the boundary. A realization for such a boundary is studied in terms of a slab of special wave-guiding anisotropic material. It is shown that analytic expressions can be found for the material parameters and thickness of the slab as functions of the complex vectors a and b. Application of a generalized soft-and-hard boundary as a polarization transformer is studied in detail.
A Study of Single-Surface Corrugated Guides (1951)

A series of experiments were conducted to determine the properties of single-surface corrugated structures as transmission lines and as radiators. Two types of surfaces were tested: the first is a flat grooved plate fed by a waveguide; the second, a circular, corrugated cylinder fed by a coaxial line. A modification of the second type results in a spirally grooved rod with similar properties. The measured field parameters are found to be predictable from existing theory. For properly designed structures the energy is essentially bound to the corrugated surface; little radiation occurs, and the attenuation of the traveling wave is due chiefly to losses in the metal. The effect of filling the corrugations with solid dielectric is also analyzed.
Canonical dynamics: Equilibrium phase-space distributions (1985)

Nos\'e has modified Newtonian dynamics so as to reproduce both the canonical and the isothermal-isobaric probability densities in the phase space of an N-body system. He did this by scaling time (with s) and distance (with ${V}^{1/D}$ in D dimensions) through Lagrangian equations of motion. The dynamical equations describe the evolution of these two scaling variables and their two conjugate momenta ${p}_{s}$ and ${p}_{v}$. Here we develop a slightly different set of equations, free of time scaling. We find the dynamical steady-state probability density in an extended phase space with variables x, ${p}_{x}$, V, \ensuremath{\epsilon}\ifmmode \dot{}\else \.{}\fi{}, and \ensuremath{\zeta}, where the x are reduced distances and the two variables \ensuremath{\epsilon}\ifmmode \dot{}\else \.{}\fi{} and \ensuremath{\zeta} act as thermodynamic friction coefficients. We find that these friction coefficients have Gaussian distributions. From the distributions the extent of small-system non-Newtonian behavior can be estimated. We illustrate the dynamical equations by considering their application to the simplest possible case, a one-dimensional classical harmonic oscillator.
Compensation of Crosstalk in Three-Axial Induction Magnetometers (2011)

A method for the compensation of crosstalk in three-axial induction magnetometers is developed theoretically and verified experimentally. The compensation is based on deriving crosstalk-free magnetometer outputs from a system of equations describing the magnetometer total outputs as a function of the applied field, the parameters of the magnetometer coils, and the crosstalk factors for the applied and secondary magnetic fluxes. Processing the total outputs of an experimental magnetometer has demonstrated an effective reduction of the crosstalk: it has been reduced below 0.5% in the whole magnetometer bandwidth, including the frequencies near resonance, where the crosstalk is especially strong (20%). In comparison, the reduction of the crosstalk by applying magnetic feedback is much less effective: the crosstalk has been reduced down to 6% at resonance, remained unchanged at low and high frequencies, and even increased just below resonance. Moreover, magnetic feedback flattens the frequency response and significantly reduces the magnetometer selectivity, which can be advantageous in many applications. Employing magnetic feedback also increases the magnetometer complexity and its power consumption.
Calibration of third-order nonlinear optical susceptibilities via non-phase matched optical third-harmonic generation in noncentrosymmetric media (2000)

Summary form only given. One of the great challenges in nonlinear optics is the establishment of reliable absolute values of optical nonlinearities. We here show that frequency-tripling in combination with cascaded second-harmonic and sum-frequency-generation is a veri efficient tool to obtain self-consistent reliable reference values for the third-order nonlinear optical susceptibility /spl chi//sup (3)/. We present our experimental results on the crystals KNbO/sub 3/, quartz, and 4-N-N-dimethylamino-4'-N'-methylstilbazolium toluene-p-sulfonate (DAST) and the glasses BK7, SF59, and fused silica with emphasis on the theoretical analysis of the cascaded phenomena including the boundary conditions, reliable reference materials, wavelength dispersion of the third-order susceptibilities, and structure-property relationships.
Approaches to site-directed DNA integration based on transposases and retroviral integrases (2011)

The ability of retroviruses and transposons to insert their genome into the host cell makes them attractive objects for constructing gene therapy vectors. However, enzymes that insert genetic material do not possess any selectivity relative to target nucleotide sequences, which results in almost random DNA insertion into the recipient cell genome. This leads to mutations that in turn may cause certain undesirable consequences and sometimes neoplastic cell transformation. For successful functioning, it is a primary necessity to modify a retrovirus and transposon based genetic therapy systems in such a way that the directed vector integration into a target sequence in the human genome can be achieved. In this review, the approaches to date that have been developed for highly specific modification of the genome using fusion protein construction based on retroviral integrases and transposases are discussed, as well as cellular factors interacting with these enzymes.
Perspectives on immunomodulation early in life (2012)

The immune system early in life is characterized by immature activation and function of immune cells and a preponderance of Th2 cytokines. Together with other factors such as genetics and epigenetics, these immature immune responses might prone newborns susceptible to severe infections as well as allergic diseases. Immunomodulation therapy may have potential as therapeutic strategy against those disorders and might have implication in early-life interventions in the future. In this review, we will focus on two immunomodulatory substance classes, Toll-like receptor (TLR) ligands and sphingolipids, which are the focus of extensive research to date. Both TLRs and sphingolipid receptors have a very distinct distribution pattern and function on immune cells. Therefore, they can potentially modulate and balance immune responses, which might be in particular beneficial for the immaturity of the immune response early in life.