gebhart/patrepeval huggingface dataset:
Residential Microgrid Scheduling Based on Smart Meters Data and Temperature Dependent Thermal Load Modeling (2013)

One of the important points in optimal operation of a micro-CHP based microgrids (e.g., a residential building) is to coordinate its thermal and electrical loads. Therefore, in this study, thermal load is analyzed more precisely in terms of the required hot water and desired building temperature. The microgrid is assumed to be equipped with smart meters and controllable electrical loads. The information provided by smart meters is utilized in implementing smart control of micro-CHP, storages, and demand response programs. This study is aimed at presenting an optimal scheduling model for a microgrid considering technical and economical constraints based on temperature dependent thermal load modeling. A sensitivity analysis is conducted to identify and rank the impact of several uncertainties such as variations in temperature, electrical and thermal demand.
Why are neural networks sometimes much more accurate than decision trees: an analysis on a bio-informatics problem (2004)

Bio-informatics data sets may be large in the number of examples and/or the number of features. Predicting the secondary structure of proteins from amino acid sequences is one example of high dimensional data for which large training sets exist. The data from the KDD Cup 2001 on the binding of compounds to thrombin is another example of a very high dimensional data set. This type of data set can require significant computing resources to train a neural network. In general, decision trees will require much less training time than neural networks. There have been a number of studies on the advantages of decision trees relative to neural networks for specific data sets. There are often statistically significant, though typically not very large, differences. Here, we examine one case in which a neural network greatly outperforms a decision tree; predicting the secondary structure of proteins. The hypothesis that the neural network learns important features of the data through its hidden units is explored by a using a neural network to transform data for decision tree training. Experiments show that this explains some of the performance difference, but not all. Ensembles of decision trees are compared with a single neural network. It is our conclusion that the problem of protein secondary structure prediction exhibits some characteristics that are fundamentally better exploited by a neural network model.
An Automatic Calibration Method for PTZ Camera in Expressway Monitoring System (2009)

Camera vision calibration is the key technology of Video-based Traffic Monitoring System (VTMS). PTZ camera is used more and more widely in the VTMS for its high flexibility and mobility which also bring great difficulties in its calibration. This paper presented an automatic method of calibration for PTZ camera used in Expressway Monitoring System so that the system can implement calibration without any manual intervention as soon as the operator changes the situation of the camera. A novel model of traffic monitoring camera is given in the beginning, a theoretical framework is established, aimed at computing all the unknown parameters in the model. Test results using real data are described. Both accuracy and speed are reported. Implementation ways and steps of practical application in the project are given.
Design and Implementation of Graphical User Interface of Digital STB (2012)

regards the development of a digital Set-Top-Box(STB) as the background, through an understanding of developing environment of graphical user interface 'GUI', To have a general design of STB GUI system'and To realize the STB GUI, and give a realized example of building an GUI under this system.
Interfacial Activation of Triglyceride Lipase from <i>Thermomyces (Humicola) lanuginosa</i>:  Kinetic Parameters and a Basis for Control of the Lid (1998)

A strategy is developed to analyze steady-state kinetics for the hydrolysis of a soluble substrate partitioned into the interface by an enzyme at the interface. The feasibility of this approach to obtain interfacial primary kinetic and equilibrium parameters is demonstrated for a triglyceride lipase. Analysis for phospholipase A2 catalyzed hydrolysis of rapidly exchanging micellar (Berg et al. (1997) Biochemistry 36, 14512-14530) and nonexchangeable vesicular (Berg et al., (1991) Biochemistry 30, 7283-7291) phospholipids is extended to include the case of a substrate that does not form the interface. The triglyceride lipase (tlTGL) from Thermomyces (formerly Humicola) lanuginosa hydrolyzes p-nitrophenylbutyrate or tributyrin partitioned in the interface of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol (POPG) vesicles at a rate that is more than 100-fold higher than that for the monodispersed substrate or for the substrate partitioned into zwitterionic vesicles. Catalysis and activation is not seen with the S146A mutant without the catalytic serine-146; however, it binds to the POPG interface with the same affinity as the WT. Thus POPG acts as a diluent surface to which the lipase binds in an active, or "open", form for the catalytic turnover; however, the diluent molecules have poor affinity for the active site. Analysis of the substrate and the diluent concentration dependence of the rate of hydrolysis provides a basis for the determination of the primary interfacial catalytic parameters. As a competitive substrate, tributyrin provided a check for the apparent affinity parameters. Nonidealities from the fractional difference in the molecular areas in interfaces are expressed as the area correction factor and can be interpreted as a first-order approximation for the interfacial activity coefficient. The basis for the interfacial activation of tlTGL on anionic interface is attributed to cationic R81, R84, and K98 in the "hinge" around the 86-93 "lid" segment of tlTGL.
Nanoparticles of Adaptive Supramolecular Networks Self-Assembled from Nucleotides and Lanthanide Ions (2009)

Amorphous nanoparticles of supramolecular coordination polymer networks are spontaneously self-assembled from nucleotides and lanthanide ions in water. They show intrinsic functions such as energy transfer from nucleobase to lanthanide ions and excellent performance as contrast enhancing agents for magnetic resonance imaging (MRI). Furthermore, adaptive inclusion properties are observed in the self-assembly process: functional materials such as fluorescent dyes, metal nanoparticles, and proteins are facilely encapsulated. Dyes in these nanoparticles fluoresce in high quantum yields with a single exponential decay, indicating that guest molecules are monomerically wrapped in the network. Gold nanoparticles and ferritin were also wrapped by the supramolecular shells. In addition, these nucleotide/lanthanide nanoparticles also serve as scaffolds for immobilizing enzymes. The adaptive nature of present supramolecular nanoparticles provides a versatile platform that can be utilized in a variety of applications ranging from material to biomedical sciences. As examples, biocompatibility and liver-directing characteristics in in vivo tissue localization experiments are demonstrated.
Neuromorphic pitch attitude regulation of an underwater telerobot (1990)

The experimental results of using trained neural networks to regulate the pitch attitude of an underwater telerobot are presented. The neuromorphic control algorithm developed for teaching the networks is a direct application of the back-propagation entrainment method, with those modifications required to pose the problem in a control systems framework. The networks perform in the field as predicted by simulation results; however, it is observed that the complexity of the calculations required can create unacceptable delays when using a single serial microprocessor to compute the control. This problem becomes especially acute when scaling the architecture to more complex neural topologies. Special-purpose hardware, which directly implements the neural equations and, hence, realizes the benefits of the natural parallelism of these models, is seen as a necessary development for the effective use of neural controllers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Accurate and scalable multi-element graph neural network force field and molecular dynamics with direct force architecture (2020)

Data includes the the ab initio molecular dynamic simulation of Li7P3S11 that was used to measure the performance of the GNNFF. The data is divided into training and testing sets. Brief descirption of the work: Recently, machine learning (ML) has been used to address the computational cost that has been limiting ab initio molecular dynamics (AIMD). Here, we present GNNFF, a graph neural network framework to directly predict atomic forces from automatically extracted features of the local atomic environment that are translationally-invariant, but rotationally-covariant to the coordinate of the atoms. We demonstrate that GNNFF not only achieves high performance in terms of force prediction accuracy and computational speed on various materials systems, but also accurately predicts the forces of a large MD system after being trained on forces obtained from a smaller system. Finally, we use our framework to perform an MD simulation of Li7P3S11, a superionic conductor, and show that resulting Li diffusion coefficient is within 14% of that obtained directly from AIMD. The high performance exhibited by GNNFF can be easily generalized to study atomistic level dynamics of other material systems.
Hereditary Inclusion Body Myopathy Maps to Chromosome 9p1-q1 (1996)

Hereditary inclusion body myopathy (HIBM) is a unique disorder of unknown etiology that typically occurs in individuals of Persian Jewish descent. Distinguishing features of the disorder from other limb girdle myopathies include elderly age of onset, ethnic predisposition, and sparing of the quadriceps despite severe involvement of all other proximal leg muscles. Involved muscles demonstrate fibers with rimmed vacuoles and filamentous cytoplasmic and nuclear inclusions. Additional histological features are accumulations of beta-amyloid protein and the absence of inflammatory cells. To identify the chromosomal location of the gene responsible for HIBM, nine Persian Jewish families with HIBM were evaluated. Genomewide linkage analyses identified the recessive IBM locus on chromosome 9 band p1-q1 (maximum lod score at D9S166 = 5.32, theta = 0.0). This region contains the Friedreich's Ataxia gene, raising the possibility that HIBM may be a related neurogenic disorder.
Bioactive Guanidine Alkaloids from Two Caribbean Marine Sponges (2009)

Seven new guanidine alkaloids (1-7) together with the known batzelladines A, F, H, and L, ptilomycalin A, and fromiamycalin were isolated from the Caribbean marine sponges Monanchora arbuscula and Clathria calla. Molecular structures were assigned on the basis of detailed analysis of 1D and 2D NMR spectra and mass spectrometry data, and bioactivities of the alkaloids were evaluated against human cancer cell lines and malaria protozoa.
Fibre-optic magnetic sensor utilising metal-coated fibre (1987)

A metal-coated fibre was injected with an electric current into its jacket for magnetic field detection using a Lorentzian force. AC and DC field detection sensitivities of 25rad/Gs and 15-7rad/Gs and linearity over four decades have been obtained with a 100 mm sensing fibre. This configuration can also be extended to multiplexed DC magnetic sensors.
A common speed limit for RNA-cleaving ribozymes and deoxyribozymes (2003)

It is widely believed that the reason proteins dominate biological catalysis is because polypeptides have greater chemical complexity compared with nucleic acids, and thus should have greater enzymatic power. Consistent with this hypothesis is the fact that protein enzymes typically exhibit chemical rate enhancements that are far more substantial than those achieved by natural and engineered ribozymes. To investigate the true catalytic power of nucleic acids, we determined the kinetic characteristics of 14 classes of engineered ribozymes and deoxyribozymes that accelerate RNA cleavage by internal phosphoester transfer. Half approach a maximum rate constant of approximately 1 min(-1), whereas ribonuclease A catalyzes the same reaction approximately 80,000-fold faster. Additional biochemical analyses indicate that this commonly encountered ribozyme "speed limit" coincides with the theoretical maximum rate enhancement for an enzyme that uses only two specific catalytic strategies. These results indicate that ribozymes using additional catalytic strategies could be made that promote RNA cleavage with rate enhancements that equal those of proteins.
Tinnitus Retraining Therapy (TRT) as a Method for Treatment of Tinnitus and Hyperacusis Patients (2000)

The aim of this paper is to provide information about the neurophysiologic model of tinnitus and Tinnitus Retraining Therapy (TRT). With this overview of the model and therapy, professionals may discern with this basic foundation of knowledge whether they wish to pursue learning and subsequently implement TRT in their practice. This paper provides an overview only and is insufficient for the implementation of TRT.
Environmental Effects on Soybean (Glycine Max (L.) Merr) Production in Central and South Germany (2020)

The cultivation area of soybean (Glycine max (L.) Merr) is increasing in Germany as a way to ensure self-sufficiency through its use as feed and food. However, climatic conditions needed for soybean cultivation are not appropriate in all parts of the country. The objective of this study was to determine the influence of solar radiation, temperature, and precipitation on soybean seed productivity and quality in central and south Germany. A multi-factorial field trial was carried out with three replicates at four locations in 2016 and five locations in 2017, testing 13 soybean varieties from the maturity groups MG 00 and MG 000. Considering all the tested factors, “variety” was highly significant concerning protein content (Ø 41.1% dry matter (DM)) and oil content (Ø 19.1% in DM), but not seed yield (Ø 40.5 dt ha−1).The broad sense heritability of protein content was H2 = 0.80 and of oil content H2 = 0.7. Protein and oil content were significantly negatively correlated (r = −0.82). Seed yield was significantly positively correlated with solar radiation (r = 0.32) and precipitation (r = 0.33), but significantly negatively with Crop Heat Units (CHU) (r = −0.42). Over both experimental years, varieties from maturity group MG 00 were less significantly correlated with the tested environmental factors than varieties from maturity group MG 000. None of the environmental factors tested significantly increased the protein or oil content of soybean. In growing areas with heat periods during ripening, protein content tended to be higher than in cooler areas; in areas with high solar radiation during flowering, protein content tended to be reduced.
Multifunctional Doped Semiconductor Nanocrystals (2012)

Multifunctional nanomaterials with combined magnetic and optical properties remain one of the most demanded materials in upcoming research. To obtain these materials, we report here several doped semiconductor nanocrystals that simultaneously show tunable emission in a visible and NIR spectral window, above-room-temperature ferromagnetism, and improved conductivity. These nanocrystals are designed by inserting Ni(II) as a dopant in various semiconducting hosts with binary, alloyed, and ternary composition, and the induced multifunctional properties are observed to be stable and reproducible. These semiconducting materials combined with fluorescence and magnetic properties would be useful for a wide range of applications spanning from life science to modern developing device technology.
Recent updates on the role of microRNAs in prostate cancer (2012)

MicroRNAs (miRNAs) are short non-coding RNAs that are involved in several important biological processes through regulation of genes post-transcriptionally. Carcinogenesis is one of the key biological processes where miRNAs play important role in the regulation of genes. The miRNAs elicit their effects by binding to the 3' untranslated region (3'UTR) of their target mRNAs, leading to the inhibition of translation or the degradation of the mRNA, depending on the degree of complementary base pairing. To-date more than 1,000 miRNAs are postulated to exist, although the field is moving rapidly. Currently, miRNAs are becoming the center of interest in a number of research areas, particularly in oncology, as documented by exponential growth in publications in the last decade. These studies have shown that miRNAs are deregulated in a wide variety of human cancers. Thus, it is reasonable to ask the question whether further understanding on the role of miRNAs could be useful for diagnosis, prognosis and predicting therapeutic response for prostate cancer (PCa). Therefore, in this review article, we will discuss the potential roles of different miRNAs in PCa in order to provide up-to-date information, which is expected to stimulate further research in the field for realizing the benefit of miRNA-targeted therapeutic approach for the treatment of metastatic castrate resistant prostate cancer (mCRPC) in the near future because there is no curative treatment for mCRPC at the moment.
Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine (2017)

The leading malaria vaccine in development is the circumsporozoite protein (CSP)-based particle vaccine, RTS,S, which targets the pre-erythrocytic stage of Plasmodium falciparum infection. It induces modest levels of protective efficacy, thought to be mediated primarily by CSP-specific antibodies. We aimed to enhance vaccine efficacy by generating a more immunogenic CSP-based particle vaccine and therefore developed a next-generation RTS,S-like vaccine, called R21. The major improvement is that in contrast to RTS,S, R21 particles are formed from a single CSP-hepatitis B surface antigen (HBsAg) fusion protein, and this leads to a vaccine composed of a much higher proportion of CSP than in RTS,S. We demonstrate that in BALB/c mice R21 is immunogenic at very low doses and when administered with the adjuvants Abisco-100 and Matrix-M it elicits sterile protection against transgenic sporozoite challenge. Concurrent induction of potent cellular and humoral immune responses was also achieved by combining R21 with TRAP-based viral vectors and protective efficacy was significantly enhanced. In addition, in contrast to RTS,S, only a minimal antibody response to the HBsAg carrier was induced. These studies identify an anti-sporozoite vaccine component that may improve upon the current leading malaria vaccine RTS,S. R21 is now under evaluation in Phase 1/2a clinical trials.
OXYGEN-SORPTIVE PROPERTIES OF DEFECT PEROVSKITE-TYPE La1−xSrxCo1−yFeyO3−δ (1985)

Abstract The substitution of Fe for Co of La1−xSrxCoO3−δ makes it possible to preserve perovskite-type structure at higher Sr contents. While the amount of oxygen reversibly absorbed or desorbed was mostly determined by the Sr content, the Fe substitution was found to enhance the oxygen desorption particularly in a lower temperature region as well as catalytic activities.
Oxidative Cyclization Reactions of Trienes and Dienynes: Total Synthesis of Membrarollin (2009)

Trienes and dienynes containing one electron-deficient double bond were shown to undergo regio- and stereoselective oxidative cyclization in the presence of permanganate ion to afford 2,5-bis-hydroxyalkyltetrahydrofurans (THF diols). The THF diols produced retained either alkene or alkyne functionalities, which provided convenient handles for the metal oxo-mediated introduction of an adjacent THF ring with overall control of relative and absolute stereochemistry. Adjacent bis-THFs possessing threo-cis-threo-trans-erythro, threo-cis-threo-trans-threo, threo-cis-threo-cis-erythro, threo-cis-erythro-cis-threo, or threo-cis-erythro-trans-threo relationships were synthesized by appropriate selection of alkene geometry and methodology for the closure of the second ring. The threo-cis-threo-cis-erythro stereochemical arrangement is embodied within the bis-THF core units of a number of Annonaceous acetogenins including membrarollin, while trilobacin has a threo-cis-erythro-trans-threo configured core. As an application of the selective oxidative cyclization approach, a total synthesis of membrarollin was completed in 17 linear steps from dodecyne. The C21,C22 double epimer of membrarollin was also synthesized in 15 linear steps and without recourse to the use of hydroxyl group protection.
Optical Consideration In Target Alignment Using Non-Actinic Wavelength Microscope (1987)

One of the most important -features of photolithographic equipment is the automatic wafer alignment capability. As the resolution of wafer steppers approaches 0.5 micron, alignment accuracy must be improved correspondingly. In addition, the wafer alignment accuracy must be insensitive to process variations. However, recent photoresist technology developments have introduced a number of highly absorbing coatings for the sake of improved resolution and better linewidth control. This includes the use of heavily dyed photoresists, antireflective coating layers, and contrast enhancement materials. With such highly absorbing photoresist coatings, it becomes difficult to see the alignment target under these coating layers. In order to achieve alignment, it is often necessary to pre-expose and develop the resist over the target, or to optically bleach the photoresist over the target by pre-alignment exposure, or to blast away the photoresist over the target using excimer lasers. In the mean time, a much better and much easier to operate approach using non-actinic alignment wavelength microscope 'b has been developed by ASET. This new approach overcomes the difficulty of seeing the alignment target by shifting the alignment wavelength to the blue-green part of the optical spectrum where practically all of these exotic process layers become transparent. It is also compatible with existing TV based alignment microscope regardless of whether it is set-up with the bright field or the dark-field schemes. In this paper more technical details of this subsystem will be reported.Data acquired on some of the most difficult customer wafers will be presented.
Incidence of Nonarteritic and Arteritic Anterior Ischemic Optic Neuropathy (1994)

This population-based study was undertaken to obtain information on age-, sex-, and race-specific incidence of nonarteritic and arteritic anterior ischemic optic neuropathy for the State of Missouri and for Los Angeles County, California. Among subjects who were 50 or older the estimated mean annual incidence rates per 100,000 population were 2.30 for nonarteritic anterior ischemic optic neuropathy and 0.36 for arteritic anterior ischemic optic neuropathy. White individuals appear to be at significantly higher risk of developing nonarteritic anterior ischemic optic neuropathy than black or Hispanic individuals, suggesting possible genetic predisposition.
Synthesis and Antitumor Activity Evaluation of Pyrimidine Analogues Bearing Urea Moiety (2014)

Abstract A series of 4‐anilino‐6‐phenylpyrimidines containing urea moiety were synthesized and the structures of all products were confirmed by 1 H NMR, 13 C NMR and HRMS. The antiproliferative activities of these compounds were evaluated against three human tumor cell lines (MGC‐803, MCF‐7 and EC‐109) by applying the MTT assay method. compounds 4a , 4b and 6a showed the most effective activity, among which, 6a was more cytotoxic than 5‐fluorouracil against all tested human cancer cell lines with IC 50 values ranging from 1.80 to 2.72 µmol·L −1 .