gebhart/patrepeval huggingface dataset:
High temperature Seebeck coefficient metrology (2010)

We present an overview of the challenges and practices of thermoelectric metrology on bulk materials at high temperature (300 to 1300 K). The Seebeck coefficient, when combined with thermal and electrical conductivity, is an essential property measurement for evaluating the potential performance of novel thermoelectric materials. However, there is some question as to which measurement technique(s) provides the most accurate determination of the Seebeck coefficient at high temperature. This has led to the implementation of nonideal practices that have further complicated the confirmation of reported high ZT materials. To ensure meaningful interlaboratory comparison of data, thermoelectric measurements must be reliable, accurate, and consistent. This article will summarize and compare the relevant measurement techniques and apparatus designs required to effectively manage uncertainty, while also providing a reference resource of previous advances in high temperature thermoelectric metrology.
Singly resonant optical parametric oscillator basedonperiodically poled MgO:LiNbO <sub>3</sub> (2000)

The authors demonstrate an efficient quasi-phase-matched optical parametric oscillator (OPO) using periodically poled MgO-doped LiNbO3 with a 30 mm interaction length and a 0.5 mm thickness. The OPO generates signal and idler wavelengths tunable in the range of 1.48 to 1.59 and 3.78 to 3.21 µm, respectively, by using seven different poling periods.
Composition followed by differentiation between H8 and a-Bloch spaces (2009)

Key points of disagreement between the aducanumab FDA statistical review, which had primarily negative conclusions, and the clinical review, which had primarily positive conclusions, were investigated. Results from secondary endpoints in positive Study 302 were significant and these endpoints provided meaningful additional information. Findings indicate the statistical review of the aducanumab data was incorrect in a number of key areas. Greater placebo decline was not responsible for the significant results in Study 302. Correlations did exist between reduction in β-amyloid and clinical outcomes. Missing data and functional unblinding did not likely bias results. In contrast, the clinical review went too far in saying the negative results in Study 301 did not detract from the positive results in Study 302, as all clinical data should be considered in the evaluation, and the clinical review accepted the company's explanation for divergence of the results between the studies although much of the divergence remained unexplained. Interestingly, both the statistical review and the clinical review considered the available efficacy evidence despite both studies being terminated early. Implications of these findings include that the divergence in results seen in the two phase 3 aducanumab studies can be expected in other studies with similar design and analysis. Therefore, further research is needed to determine if analysis methods other than MMRM and/or optimized outcomes will provide more consistent results across studies.
New transition metal derivatives of the triborohydride ion and the first example of reversible bidentate-tridentate borane ligand functionality (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew transition metal derivatives of the triborohydride ion and the first example of reversible bidentate-tridentate borane ligand functionalityDonald F. Gaines and Steven J. HildebrandtCite this: J. Am. Chem. Soc. 1974, 96, 17, 5574–5576Publication Date (Print):August 1, 1974Publication History Published online1 May 2002Published inissue 1 August 1974https://pubs.acs.org/doi/10.1021/ja00824a048https://doi.org/10.1021/ja00824a048research-articleACS PublicationsRequest reuse permissionsArticle Views128Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A RAM-based neural network for collision avoidance in a mobile robot (2004)

A RAM-based neural network is being developed for a mobile robot controlled by a simple microprocessor system. Conventional neural networks often require a powerful and sophisticated computer system. Training a multi-layer neural network requires repeated presentation of training data, which often results in very long learning time. The goal for this paper is to demonstrate that RAM-based neural networks are a suitable choice for embedded applications with few computational resources. This functionality is demonstrated in a simple robot powered by an 8051 microcontroller with 512 bytes of RAM. The RAM-based neural network allows the robot to detect and avoid obstacles in real time.
Semantically similar document retrieval framework for language model speaker adaptation (2016)

The paper deals with semantically similar document retrieval framework for language model adaptation in Slovak to a specific speaker speaking style. This research extends our previous study oriented on language model speaker adaptation for transcription of Slovak parliament proceedings with available speaker-specific text data. We used a large corpora for retrieving semantically similar subset of text documents for each speaker to adjust parameters of an existing well-trained language model to a specific speaker speaking style. The same large corpora was used to build original topic-specific model of the Slovak language deployed in our automatic subtitling system. In the proposed framework, the latent semantic indexing was implemented to retrieve the subset of semantically similar documents. The output hypotheses from the first step of speech recognition were used to identify patterns between terms and concepts contained in an unstructured collection of text documents. Preliminary results show a slight improvement in speech recognition accuracy for individual speaker in fully automatic subtitling of parliament speech, broadcast news TV shows and TEDx talks.
Humidity-Responsive Bilayer Actuators Based on a Liquid-Crystalline Polymer Network (2013)

A humidity-responsive bilayer actuator has been developed that consists of an oriented polyamide-6 substrate and a liquid-crystalline polymer coating. The oriented substrate acts as an alignment layer for the liquid crystal. The liquid-crystalline polymer consists of a supramolecular network having hydrogen-bonded entities that, after activation with an alkaline solution, exhibit deformation in response to a change in humidity. The bending behavior of the bilayer actuator was analyzed, showing a large response to a change in the humidity.
Hsp47 and Cyclophilin B Traverse the Endoplasmic Reticulum with Procollagen into Pre-Golgi Intermediate Vesicles (1995)

Hsp47 and cyclophilin B (CyPB) are residents of the endoplasmic reticulum (ER). Both of these proteins are closely associated with polysome-associated alpha 1(I) procollagen chains. Hsp47 possesses chaperone properties early during the translation of procollagen while the cis/trans-isomerase properties of CyPB facilitate procollagen folding. In this report, we further investigate the interaction of these proteins with procollagen I during export from the ER. To inhibit vesicular budding and retain procollagen within the ER, cells were treated with the heterotrimeric G protein inhibitor mastoparan or calphostin C, a specific inhibitor of diacylglycerol/phorbol ester binding proteins. To arrest procollagen in pre-Golgi intermediate vesicles, cells were treated with guanosine 5'-3-O-(thio)triphosphate. Pulse-chase experiments of cells labeled with [35S]methionine followed by immunoprecipitation during the chase period with anti-procollagen, anti-Hsp47, and anti-CyPB antibodies were performed to reveal the relationship between Hsp47/CyPB/procollagen I. The distribution of procollagen, Hsp47, and CyPB to the ER and/or pre-Golgi vesicles was verified by immunofluorescence. Hsp47 and CyPB remained associated with procollagen retained within the ER. Hsp47 and CyPB were also associated with procollagen exported from the ER into pre-Golgi intermediate vesicles. Treatment of cells with cyclosporin A diminished the levels of CyPB bound to procollagen and diminished the rate of Hsp47 released from procollagen and the rate of procollagen secretion, suggesting that Hsp47 release from procollagen may be driven by helix formation. Also, these studies suggest that Hsp47 may resemble protein disulfide isomerase and possess both chaperone and anti-chaperone properties. During translation, high levels of Hsp47 are seen to limit protein aggregation and facilitate chain registration. Later, Hsp47 and/or CyPB and protein disulfide isomerase act as anti-chaperones and provide the basis for concentration of procollagen for ER export.
Rash to the mTOR Inhibitor Everolimus (2012)

Everolimus is associated with a significant risk of developing a rash. Management of rash to everolimus is critical to prevent dose modifications and decreased quality of life, both of which can negatively affect overall clinical outcomes.
An integrated audio and active noise control system (2002)

The authors present an integrated three-dimensional active noise control (ANC) method with an existing audio system to reduce annoying low frequency noise. The hybrid ANC-audio system utilizes adaptive signal processing to reduce unwanted acoustic noise in the passenger compartment of a car, thus enhancing an audio source. The musical interference suppression process, which reduces the interference of musical signals in the updates of the ANC filter, also provides an optimal method for online error-path modeling. Computer simulations were conducted to verify the capabilities of interference suppression and online modeling.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques (2015)

The increasing interest and recent developments in nanotechnology pose previously unparalleled challenges in understanding the effects of nanoparticles on living tissues. Despite significant progress in in vitro cell and tissue culture technologies, observations on particle distribution and tissue responses in whole organisms are still indispensable. In addition to a thorough understanding of complex tissue responses which is the domain of expert pathologists, the localization of particles at their sites of interaction with living structures is essential to complete the picture. In this review we will describe and compare different imaging techniques for localizing inorganic as well as organic nanoparticles in tissues, cells and subcellular compartments. The visualization techniques include well-established methods, such as standard light, fluorescence, transmission electron and scanning electron microscopy as well as more recent developments, such as light and electron microscopic autoradiography, fluorescence lifetime imaging, spectral imaging and linear unmixing, superresolution structured illumination, Raman microspectroscopy and X-ray microscopy. Importantly, all methodologies described allow for the simultaneous visualization of nanoparticles and evaluation of cell and tissue changes that are of prime interest for toxicopathologic studies. However, the different approaches vary in terms of applicability for specific particles, sensitivity, optical resolution, technical requirements and thus availability, and effects of labeling on particle properties. Specific bottle necks of each technology are discussed in detail. Interpretation of particle localization data from any of these techniques should therefore respect their specific merits and limitations as no single approach combines all desired properties.
Behavior of Salicylaldoxime and 8‐Hydroxyquinoline at a Copper Electrode (1975)

Effects of salicylaldoxime (SAO) and of 8‐hydroxyquinoline (HQ) on the anodic dissolution of copper were studied by using a potentiokinetic polarization method and phase‐selective a‐c polarography at a rotating copper disk electrode at various pH values. At pH 1.5, where cupric ions do not precipitate as the chelates of SAO and HQ, the anodic dissolution of copper was retarded slightly by these additives. At pH 2.8 and 5.0, where SAO precipitates cupric ions quantitatively, the anodic dissolution of copper was markedly retarded by SAO, especially from the rotating disk electrode. The anodic polarization curves of copper in the SAO solutions were similar to those obtained in the passivation of iron. A thin protective chelate film was formed on the copper electrode. At very positive potentials, the chelate film ruptured and the anodic dissolution of copper started. On the other hand, HQ chemisorbed strongly on the copper electrode from pH 2.8–5.0, where HQ also precipitates cupric ions, and the copper dissolution was retarded markedly. The Cu‐HQ chelate did not act as a barrier for the copper dissolution in this pH range.
3D inductive power transfer power system (2014)

To date, the technique of inductive power transfer has found applications in industry including two-dimensional battery charging. However, this restricts any load to planar movements. This paper proposes custom designed magnetic structures of a loosely magnetically coupled three-dimensional inductive power transfer system. This is done via computational software utilizing the finite-element-method. More specifically, single-phase and multi-phase primary magnetic structures are proposed to distribute a power transfer window along three orthogonal axes. Next, a secondary magnetic structure is custom designed to induce electromotive force in three-dimensions. The proposed system is simulated to demonstrate power transfer for charging an AA-battery cell. Finally, the thermal effects upon the secondary load are considered.
Adenosine type 1 receptor antagonists in fluid retaining disorders (2002)

Adenosine is a vasoactive hormone whose action is mediated through at least four receptors. The most prevalent receptors are type 1, which promote vasoconstriction, and type 2, comprised of 2 subtypes (a,b) that promote vasodilation. In the kidney, type 1 receptors located on preglomerular vessels and in the tubule are involved in the regulation of glomerular filtration. Whole body fluid balance is strongly dependent on the ability of the kidney to maintain stable glomerular filtration. Several antagonists to adenosine type 1 receptors have been developed. These agents generate excess fluid (diuresis) and sodium (natriuresis) excretion in control animals and animal models of fluid retention, as well as in normal and oedematous humans. In both animals and humans, these effects are generally achieved without major changes in glomerular filtration. Animal studies have confirmed the location of adenosine type 1 receptors in relevant tissue sites in the kidney. More highly selective antagonists for adenosine type 1 receptors are regularly developed, improving their use in fluid retaining disorders. Clinical trials with these agents have commenced for the treatment of hypertension, renal failure and congestive heart failure, all disorders that include varying levels of fluid retention. The clinical trial results have been mixed. The early results with congestive heart failure suggest great promise for these agents, whereas trials in hypertension and renal failure have been equivocal.
Nanoscale Calorimetry Using a Suspended Bridge Configuration (2007)

Abstract A new setup for small-scale differential scanning calorimetry (DSC) studies based on a suspended bridge configuration is presented. The new setup has three major advantages over previously reported DSC setups: 1) superior temperature uniformity in the bridge cross section; 2) less heat loss to the surroundings by at least two orders of magnitude; and 3) a faster transient response by three orders of magnitude. This paper includes a thermal analysis to support these improvements. A major contribution of the new thermal analysis over previous reports is the inclusion of the thermal mass of the substrate in calculations, which makes thermal design more detailed, dramatically affecting accuracy and sensitivity in measurements. Furthermore, the new thermal analysis more accurately accounts for heat loss to the substrate and the surroundings in efforts to resolve suspected inconsistencies in previously reported data. Experimental validation of the new setup is presented by measuring the specific heat of thin layers of Si0 <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and CoFe. The specific heat of Si0 <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> was found to be 2.2 times 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> Jm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> K <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> which is nearly 10% different from the literature values of bulk specimens. For CoFe, the specific heat value of 3.16 x 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> Jm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> K <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> is obtained using differential Cu/Si0 <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and Cu/Si0 <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /CoFe structures compared to the value of 3.5 times 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> Jm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> K <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> obtained using single CoFe suspended structure.
Impairment of EEG desynchronisation before and during movement and its relation to bradykinesia in Parkinson's disease (1999)

The results are consistent with the idea that the basal ganglia liberate frontal cortex from idling rhythms, and that this effect is focused and specific in so far as it changes with the demands of the task. In particular, the effective selection and execution of more complex tasks is associated with changes over the prefrontal cortex.
High Quality, Low Power QMF Bank Design for SBR, Parametric Coding, and MPEG Surround Decoders (2007)

Due to the aliasing-free properties, the complex quadrature mirror filter (QMF) bank has been used in MPEG-4 audio standard on SBR, parametric, and surrounds coding. The high complexity overhead from the complex QMF bank and the complex data processing in the decoder leads to the development of low power decoder which adopts the real QMF bank as the basic building module to reduce the complexity. However the artifacts from the aliasing in the real QMF bank are the major concern. This paper studies the artifacts from the real QMF bank and proposes a novel QMF bank design to achieve both low complexity and high quality. Also, this paper applies the novel QMF bank to develop the high-quality and low-power SBR, parametric, and MPEG surround decoders and shows the merits in complexity and quality.
Identification of Virulence Genes in a Pathogenic Strain of<i>Pseudomonas aeruginosa</i>by Representational Difference Analysis (2002)

Pseudomonas aeruginosa is an opportunistic pathogen that may cause severe infections in humans and other vertebrates. In addition, a human clinical isolate of P. aeruginosa, strain PA14, also causes disease in a variety of nonvertebrate hosts, including plants, Caenorhabditis elegans, and the greater wax moth, Galleria mellonella. This has led to the development of a multihost pathogenesis system in which plants, nematodes, and insects have been used as adjuncts to animal models for the identification of P. aeruginosa virulence factors. Another approach to identifying virulence genes in bacteria is to take advantage of the natural differences in pathogenicity between isolates of the same species and to use a subtractive hybridization technique to recover relevant genomic differences. The sequenced strain of P. aeruginosa, strain PAO1, has substantial differences in virulence from strain PA14 in several of the multihost models of pathogenicity, and we have utilized the technique of representational difference analysis (RDA) to directly identify genomic differences between P. aeruginosa strains PA14 and PAO1. We have found that the pilC, pilA, and uvrD genes in strain PA14 differ substantially from their counterparts in strain PAO1. In addition, we have recovered a gene homologous to the ybtQ gene from Yersinia, which is specifically present in strain PA14 but absent in strain PAO1. Mutation of the ybtQ homolog in P. aeruginosa strain PA14 significantly attenuates the virulence of this strain in both G. mellonella and a burned mouse model of sepsis to levels comparable to those seen with PAO1. This suggests that the increased virulence of P. aeruginosa strain PA14 compared to PAO1 may relate to specific genomic differences identifiable by RDA.
Contemporary approach to essential thrombocythemia and polycythemia vera (2015)

Risk stratification of patients with essential thrombocythemia/polycythemia vera by age and/or history of thrombosis provides the basis of risk adapted therapeutic intervention. Aggressive control of modifiable cardiovascular risk factors, the use of antiplatelet agents, control of the hematocrit less than 45% in polycythemia vera, and cytoreductive therapy in high-risk essential thrombocythemia/polycythemia vera patients is the focus of management. The exact role of IFN-α remains undefined and under active investigation, and the recent approval of ruxolitinib provides patients with polycythemia vera a second-line option.
A STUDY OF THE ACCURACY OF CYBERKNIFE SPINAL RADIOSURGERY USING SKELETAL STRUCTURE TRACKING (2007)

The Xsight spine tracking system is practically important because it is accurate and eliminates the use of implanted fiducials. Experience has shown this technology to be robust under a wide range of clinical circumstances.