gebhart/patrepeval huggingface dataset:
Sketching MLS Image Deformations On the GPU (2008)

Abstract In this paper, we present an image editing tool that allows the user to deform images using a sketch‐based interface. The user simply sketches a set of source curves in the input image, and also some target curves that the source curves should be deformed to. Then the moving least squares (MLS) deformation technique [ SMW06 ] is adapted to produce realistic deformations while satisfying the curves' positional constraints. We also propose a scheme to reduce image fold‐overs in MLS deformations. Our system has a very intuitive user interface, generates physically plausible deformations, and can be easily implemented on the GPU for real‐time performance.
Application of acoustic-electric interaction for neuro-muscular activity mapping: A review (2015)

Acousto-electric interaction signal (AEI signal) resulting from interaction of acoustic pressure wave and electrical current field has received recent attention in biomedical field for detection and registration of bioelectrical current. The signal is very of small value and brings about several challenges when detecting it. Several observations has been done in saline solution and on nerves and tissues under controlled condition that give optimistic indication about its utilization. Ultrasound Current Source Density Imaging (UCSDI) has been introduced, that uses the AEI signal to image the current distribution. This review provides an overview of the investigations on the AEI signal and USCDI imaging that has been made, their results and several considerations on the limitations and future possibilities on using the acousto-electric interaction signal.
Smart Ubiquitous Chatbot for COVID-19 Assistance with Deep learning Sentiment Analysis Model during and after quarantine (2020)

<title>Abstract</title> The huge number of deaths caused by the novel pandemic COVID-19, which can affect anyone of any sex, age and socio-demographic status in the world, presents a serious threat for humanity and society. At this point, there are two types of citizens, those oblivious of this contagious disaster's danger that could be one of the causes of its spread, and those who show erratic or even turbulent behavior since fear and anxiety invades our surroundings because of confinement and panic of being affected.In this paper we aim at developing a smart ubiquitous chatbot, called COVID-Chatbot, for COVID-19 assistance during and after quarantine that communicates with a citizen to increase his/her consciousness towards the real danger of this outbreak. Furthermore, COVID-Chatbot is able to recognize and manage stress, during and after lockdown and quarantine period, using natural language processing (NLP).The robust messages delivered from COVID-Chatbot and its way of communication could possibly help to slow the COVID-19 spread.The proposed method is a ubiquitous healthcare service that is presented by its four interdependent modules: Information Understanding Module (IUM) in which the NLP is done, Data Collector Module (DCM) that collect user's non-confidential information to be used later by the Action Generator Module (AGM) that generates the chatbots answers which are managed through its three sub-modules. And finally the Depression Detector Model (DDM) that detects anxiety in the text input through a deep leaning sentiment analysis model to help AGM make the decision to deliver a reassurance message if a bad behavior is distinguished.
Pulse shaping for mode-selective ultrafast coherent Raman spectroscopy of highly scattering solids (2008)

We report on mode-selective ultrafast coherent anti-Stokes Raman spectroscopy (CARS) of a powder of sodium dipicolinate. We produce a pair of stretched laser pulses with precisely adjusted matching chirp rates. We use the pulses for frequency-resolved excitation of coherent molecular vibrations in this highly scattering medium. The induced oscillations are probed with the third delayed ultrashort laser pulse. Since the attained spectral width of the pump-Stokes excitation band is on the order of the spacing between the Raman lines, time-resolved CARS measurements reveal single-mode as well as double-mode coherence decay dynamics, depending on the timing between the pump and Stokes pulses. For a fixed probe pulse delay, the sweeping of the arrival time for one of the preparation pulses maps out the CARS spectrum of the analyte.
Acute myeloid leukemia—Major progress over four decades and glimpses into the future (2015)

In this Review, the progress in research and therapy of acute myeloid leukemia is detailed.
Internet Performance Survival Guide: QoS Strategies for Multiservice Networks (2000)

Internet Performance and Quality of Service. The Performance Toolkit. Performance Tuning Techniques. Quality of Service Architectures. Performance Engineering. What Is Quality of Service Anyway? Glossary.
Effects of high‐dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs clinical and immune correlates (1995)

Patients taking dietary supplements of fish oil exhibit improvements in clinical parameters of disease activity from baseline, including the number of tender joints, and these improvements are associated with significant decreases in levels of IL-1 beta from baseline. Some patients who take fish oil are able to discontinue NSAIDs without experiencing a disease flare.
Optics and actuators for miniaturized spectrometers (2002)

We propose a variety of miniaturized microelectromechanical (MEMS) spectrometers. Emphasis is put on the development of a Fourier transform spectrometer based on a Michelson interferometer. A new design of the existing chip has been realized in order to integrate an input fiber, a collimating system as well as a beam splitting plate. This new design allows to carry out spectroscopy with white light. In fact, since white light has a smaller length of coherence, the phase difference zero is extremely important to be well set, i.e. the optical path in each branch of the interferometer has to be equal. Finally, we present two other designs of spectrometers: a lamellar grating spectrometer and a Hadamard transform spectrometer.
An introduction to multi-agent statistics (2014)

Building on ideas from probabilistic dynamic epistemic logic, the aim of this workshop contribution is to present the practical details of how to build and use Bayesian models that can represent multi-agent uncertainty, including probability distributions over (other people's) probability distributions.The key insight that underlies the approach taken here is that probabilities like PA() are random variables and can be treated as such.By keeping carefully track of what various agents know under various circumstances, this way of looking at the issue provides enough structure to support queries about higher-order probabilistic belief statements.
Conformation of the synthetic DNA poly(amino<sup>2</sup>dA-dT) duplex in high-salt and aqueous alcohol solutions (1988)

It has previously been demonstrated by other workers that the duplex of a synthetic DNA poly(amino2dA-dT) undergoes a salt-induced conformational isomerization. We show in the present work using circular dichroism that the same isomerization is induced in poly(amino2dA-dT) by various alcohols. The isomerization was originally identified as the B-to-Z and then B-to-A conformational transition of DNA but we demonstrate that the high-salt or alcohol conformation of poly (amino2dA-dT) is the non Z-DNA zig-zag double helix we have previously observed with poly(dA-dT) and called X-DNA. X-DNA is a cesium cation specific conformation of poly(dA-dT) while no similar cation specificity is observed with poly(amino2dA-dT). Thus it appears that the extra amino group attached to A and cesium cations make the same thing; they probably dehydrate the double helix minor groove and relieve its conformational variability. Poly(amino2dA-dT) is exceptionally stable in X-DNA and conditions inducing it are mild, which opens the door to assess its molecular structure.
Protein-mediated error correction for de novo DNA synthesis (2004)

The availability of inexpensive, on demand synthetic DNA has enabled numerous powerful applications in biotechnology, in turn driving considerable present interest in the de novo synthesis of increasingly longer DNA constructs. The synthesis of DNA from oligonucleotides into products even as large as small viral genomes has been accomplished. Despite such achievements, the costs and time required to generate such long constructs has, to date, precluded gene-length (and longer) DNA synthesis from being an everyday research tool in the same manner as PCR and DNA sequencing. A critical barrier to low-cost, high-throughput de novo DNA synthesis is the frequency at which errors pervade the final product. Here, we employ a DNA mismatch-binding protein, MutS (from Thermus aquaticus) to remove failure products from synthetic genes. This method reduced errors by >15-fold relative to conventional gene synthesis techniques, yielding DNA with one error per 10 000 base pairs. The approach is general, scalable and can be iterated multiple times for greater fidelity. Reductions in both costs and time required are demonstrated for the synthesis of a 2.5 kb gene.
FUNCTITONAL CAPACITY OF THE ISOLATED HUMAN SPINAL CORD (1950)

Journal Article FUNCTITONAL CAPACITY OF THE ISOLATED HUMAN SPINAL CORD Get access ROBERT A. KUHN ROBERT A. KUHN Search for other works by this author on: Oxford Academic PubMed Google Scholar Brain, Volume 73, Issue 1, March 1950, Pages 1–51, https://doi.org/10.1093/brain/73.1.1 Published: 01 March 1950
Latexin exhibits tumor suppressor potential in hepatocellular carcinoma (2014)

Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver and latexin is downregulated in several types of human cancer. However, latexin expression in HCC remains unknown. mRNA expression of latexin in HCC samples and HCC-derived cell lines was detected by semi‑quantitative PCR and real-time PCR, while protein expression was assessed by immunohistochemistry. The role of latexin in the regulation of the proliferation of HCC-derived cells was investigated both in vitro and in vivo. Flow cytometry was used to differentiate cell cycle distribution in SK-hep-1 and YY-8103. In a total of 60 paired HCC specimens, compared with adjacent non-cancer tissues, latexin mRNA was downregulated in 42 specimens. Immunohistochemical analysis showed a significant reduction in latexin expression in HCC compared to control tissues. Overexpression of latexin inhibited SK-hep-1 and HepG2 cellular colony formation and tumor growth. Conversely, YY‑8103 and Focus cells transfected with shRNA enhanced colony formation and tumor growth. Latexin overexpression promoted cell cycle arrest in the G0/G1 phase in SK-hep-1 and silencing of latexin promoted the cell cycle transition from G0/G1 phase to S phase in YY-8103. The cyclin-dependent kinase inhibitors (CDKIs) (p21Cip1, p27Kip1, p15INK4B), cyclin D1 and cyclin E were shown to be differentially expressed in latexin-overexpressed cells and latexin-silenced cells. These results indicated that latexin may be an effective target for gene therapy.
<scp>Subsidization and Choice in the Group Health Insurance Market</scp> (2005)

Abstract This study investigates the effect of group health insurance plan choice on insurance unit price. The empirical findings suggest that the unit price of insurance, as measured by the ratio of the premium to expected indemnity benefits, is lower in group plans that offer employees a choice of different insurance options and require a premium contribution than it is in plans lacking at least one of these two features. The analyses suggest that lower unit prices are related to an increase in indemnity benefits and that the reduction in the unit price is greater for lower risks. The findings indicate that although subsidization of high risks by low risks occurs with group health insurance, the degree of subsidization is less when employees are offered a choice of health insurance plans.
Nature-inspired position determination using inherent magnetic fields (2014)

Many creatures in nature, including butterflies, newts, and mole rats, use the Earth's inherent magnetic field for navigation. They use magnetic field lines and variations in field intensity to determine their geographical position. This paper seeks to apply similar techniques to measure the positions of individual ferromagnetic objects found all around us in everyday life. Ferromagnetic objects have inherent magnetic fields around them. We show here that the magnetic field variation around a ferromagnetic object can be modeled using purely the geometry of the object under consideration. By exploiting this model, the position of the object can be measured quite accurately using a small inexpensive magnetic sensor. Further, the use of just one additional redundant magnetic sensor can eliminate the need to calibrate the position measurement system. As demonstrated in the paper through a series of experimental results, the developed measurement system is applicable to accurate position measurement of small and large ferromagnetic objects, including cars on highways, oscillating pistons in internal combustion engines, pneumatic cylinders, hydraulic cylinders, as well as moving parts in many machines.
An imaging‐based approach to the evaluation of xerostomia (2012)

This approach may permit site-specific assessment of xerostomia, individualized treatment planning and monitoring, and sequential mucosal mapping in patients with dry mouth.
<i>x‐f</i> choice: Reconstruction of undersampled dynamic MRI by data‐driven alias rejection applied to contrast‐enhanced angiography (2006)

A technique for reconstructing dynamic undersampled MRI data, termed "x-f choice," was developed and applied to dynamic contrast-enhanced MR angiography (DCE-MRA). Regular undersampling in k-t space (a hybrid of k-space and time) creates aliasing in the conjugate x-f space that must be resolved. When regions in the object containing fast dynamic change are sparse, as in DCE-MRA, signal overlap caused by aliasing is often much less than the undersample factor would imply. x-f Choice reconstruction identifies overlapping signals using a model of the full non-aliased x-f space that is automatically generated from the undersampled data, and applies parallel imaging (PI) to separate them. No extra reference scans are required to generate either the model or the coil sensitivity maps. At each location in the reconstructed images, g-factor noise amplification is compared with predicted reconstruction errors to obtain an optimized solution. Acceleration factors greater than the number of receiver coils are possible, but are limited by the sparseness of the dynamic content and the signal-to-noise ratio (SNR) (in DCE-MRA the latter is dominant). Temporal fidelity was validated for up to a factor 10 speed-up using retrospectively undersampled data from a six-coil array. The method was tested on volunteers using fivefold prospective undersampling.
Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage (2014)

During our life, we are surrounded by continuous threats from a diverse range of invading pathogens. Our immune system has evolved multiple mechanisms to efficiently deal with these threats so as to prevent them from causing disease. Terminal differentiation of mature B cells into plasma cells (PC) - the antibody (Ab) secreting cells of the immune system - is critical for the generation of protective and long-lived humoral immune responses. Indeed, efficient production of antigen (Ag)-specific Ab by activated B cells underlies the success of most currently available vaccines. The mature B-cell pool is composed of several subsets, distinguished from one according to size, surface marker expression, location, and Ag exposure, and they all have the capacity to differentiate into PCs. For a B-cell to acquire the capacity to produce Abs, it must undergo an extensive differentiation process driven by changes in gene expression. Two broad categories of Ags exist that cause B-cell activation and differentiation: T cell dependent (TD) or T cell independent (TI). In addition to the B-cell subset and nature of the Ag, it is important to consider the cytokine environment that can also influence how B-cell differentiation is achieved. Thus, while many cytokines can induce Ab-secretion by B cells after activation with mimics of TD and TI stimuli in vitro, they can have different efficacies and specificities, and can often preferentially induce production of one particular Ig isotype over another. Here, we will provide an overview of in vitro studies (mouse and human origin) that evaluated the role of different cytokines in inducing the differentiation of distinct B-cell subsets to the PC lineage. We will place particular emphasis on IL-21, which has emerged as the most potent inducer of terminal B-cell differentiation in humans. We will also focus on the role of IL-21 and defects in B-cell function and how these contribute to human immunopathologies such as primary immunodeficiencies and B-cell mediated autoimmune conditions.
Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art (2014)

ANCA-associated vasculitis (AAV) is a group of disorders that is caused by inflammation affecting small blood vessels. Both arteries and veins are affected. AAV includes microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) renamed from Wegener's granulomatosis, and eosinophilic granulomatosis with polyangiitis (EGPA), renamed from Churg-Strauss syndrome. AAV is primarily due to leukocyte migration and resultant damage. Despite decades of research, the mechanisms behind AAV disease etiology are still not fully understood, although it is clear that genetic and environmental factors are involved. To improve the understanding of the disease, the genetic component has been extensively studied by candidate association studies and two genome-wide association studies. The majority of the identified genetic AAV risk factors are common variants. These have uncovered information that still needs further investigation to clarify its importance. In this review, we summarize and discuss the results of the genetic studies in AAV. We also present the novel approaches to identifying the causal variants in complex susceptibility loci and disease mechanisms. Finally, we discuss the limitations of current methods and the challenges that we still have to face in order to incorporate genomic and epigenomic data into clinical practice.
Public health expenditure and the rural poor in Kenya (1994)

The paper is part of an overall review of public expenditures for Kenya, which includes analysis of health expenditures. The health expenditure analysis has been divided into two separate reports, this paper being one of them. The first report addresses the main the sectoral expenditure issues. This paper is intended to complement that report by providing analysis of the benefits to the rural poor of public health expenditures in Kenya. Most of Kenya's rural poverty is found in Rift Valley region, which accounts for just under a third of its incidence. The report is concerned only with rural Kenya because of limitations of the available data on urban health facility use. It also discusses briefly the main trends in health expenditures, assessing how the poor are likely to have been affected by them. The analysis that follows disaggregates the rural population into deciles. These preliminary results of Mukui (1993) suggest that the bottom four deciles should be treated as representing the poor in rural Kenya.
Pixelless infrared imaging devices based on the integration of an n-type quantum well infrared photodetector with a near-infrared light-emitting diode (1999)

This paper presents the recent developments of large area focal plane 'pseudo' arrays for infrared (IR) imaging. The devices (called QWIP-LED) are based on the epitaxial integration of an n-type mid-IR (8 - 10 micrometer in the present study) GaAs/AlGaAs quantum well detector with light emitting diode. The originality of this work is to use n-type quantum wells for large detection responsivity. From these structures, very large area (approximately equals cm<SUP>2</SUP>) mesas are processed with V-grooves to couple the mid-IR light with the QW intersubband transitions. The increase of spontaneous emission by the mid-infrared induced photocurrent is detected with a CCD camera in the reflection configuration. As demonstrated earlier on p-type QWIP structures the mid-IR image of a blackbody object is up-converted to a near-IR transformed image with very small distortion.
A simultaneous inversion of seismic traveltimes and amplitudes for velocity and attenuation (1996)

Abstract It is possible to efficiently use traveltime and amplitude information to infer variations in velocity and Q. With little additional computation, terms accounting for source radiation pattern and receiver coupling may be included in the inversion. The methodology is based upon a perturbation approach to paraxial ray theory. The perturbation approach linearizes the relationship between velocity deviations and traveltime and amplitude anomalies. Using the technique, we infer the velocity and attenuation structure at a fractured granitic site near Raymond, California. A set of four well pairs are examined and each is found to contain two zones of strong attenuation. The velocity variations contain an upper low velocity region corresponding to the uppermost attenuating zone. The location of these zones agrees with independent well-log and geophysical data. The velocity and attenuation anomalies appear to coincide with extensively fractured sections of the borehole and may indicate fracture zones rather than individual fractures.
Expanded health data from the new birth certificate, 2006. (2009)

There were 2,073,368 births to residents of the 19-state reporting area, representing 49 percent of 2006 U.S. births. The rate of prepregnancy diabetes was 6.8 per 1,000 births and gestational diabetes was 38.7; risk of both types of diabetes rose rapidly with advancing maternal age. Cervical cerclage was reported at a rate of 2.9 per 1,000. External cephalic version was used in 3.2 of every 1,000 births; its success rate decreased with increasing maternal age. Almost all attempts at forceps or vacuum delivery were successful. About 25 percent of women who had a cesarean delivery attempted a trial of labor. Fifteen percent of women received antibiotics during labor. Rates for antenatal steroids (8.4) and surfactant replacement therapy (3.2) decreased with increasing gestational age. Large differences by race and Hispanic origin were generally seen for the receipt of steroids and surfactant replacement therapy regardless of gestational age. Six percent of all infants were admitted to a neonatal intensive care unit (NICU).
Automatic document orientation detection and categorization through document vectorization (2006)

This paper presents an automatic orientation detection and categorization technique that is capable of detecting the orientation of multilingual documents with arbitrary skew and categorizing document images according to the underlying languages. We carry out orientation detection and categorization through document vectorization, which encodes document orientation and language information and converts each document image into an electronic document vector through the exploitation of the density and distribution of vertical component runs. For each language of interest, a pair of vector templates is first constructed through a training process. Orientation and category of the query image are then determined based on distances between the query document vector and the constructed vector templates. Experiments over 492 testing document images show that the average orientation detection and categorization rates reach up to 97.56% and 99.59%, respectively.