gebhart/patrepeval huggingface dataset:
Reasoning on Business Processes to Support Change Reuse (2011)

This paper addresses a novel reasoning approach for the creation and adaptation of business processes. Today, business processes and the underlying workflows and information systems have to be adaptable to changes as customers expect organizations to deal with their requests in a flexible, individual way. Adaptive workflow technology is a technical solution to facilitate such flexibility. However, it requires the creation and adaptation of workflows, which are both difficult modeling tasks. The paper presents on a case based assistant system that supports the users in creating and adapting workflows by automated change reuse. Novel concepts are introduced for the representation, retrieval and reuse of adaptation cases that record change episodes of workflows. The work has been motivated and is evaluated by a set of real workflows from a sample domain. The paper provides a research contribution to more flexibility of business processes in modern enterprise computing.
Dual-axes capacitive inclinometer/low-g accelerometer for automotive applications (2002)

This paper reports a dual-axes capacitive inclinometer/low-g accelerometer based on a novel feedback operation concept. The device consists of a sensor die and an ASIC, housed in a dual-in-line transfer moulded package for surface mounting. The sensor is fabricated by bulk micromachining of silicon and triple stack anodic bonding and is primarily an accelerometer sensitive to the Earth's gravitational field. Through the dedicated ASIC, the device can be programmed to operate either as a low-g accelerometer or as an inclinometer. The device is designed to have a programmable range up to /spl plusmn/2 g for the accelerometer and up to /spl plusmn/40/spl deg/ for the inclinometer, and a resolution of 0.61 mg and 0.1/spl deg/, respectively.
Accountability vs. access (2014)

Several letters to the editor are presented in response to articles published in the January/February 2014 issue, including The Right Debate and The Great Story.
Dynamic barcodes for a better ubiquitous understanding (2013)

Barcodes have survived the shift from paper to screen. Printed boarding passes and paper advertisements are substituted by mobile applications and digital billboards where barcodes remain key to exchange small amounts of information in a quick, uncomplicated way. The move to digital media opens up new opportunities for dynamic usage scenarios involving barcodes. In this paper, we explore how 2D barcodes can increase the awareness of machines in an analog world where information is primarily visualized for humans. Moreover, we exploit displays and cameras as virtual networks to transfer data using 2D barcode slideshows. Hence we address two problems conventional barcodes cope with: a constrained data capacity and a lack of semantics in the data it contains.
Estrogen Receptor Antagonist ICI182,780 Exacerbates Ischemic Injury in Female Mouse (2000)

Recent findings in animals emphasize that experimental ischemic brain damage can be strikingly reduced by estrogen: however, the neuroprotective mechanisms are not well understood. It was hypothesized that estrogen signaling via cognate estrogen receptors (ERs) within the vasculature is an important aspect of cerebral ischemic protection in the female brain, in part by amplifying intraischemic cerebral blood flow (CBF). In the present study, the hypothesis that chronic treatment with the pure ER antagonist ICI182,780 (ICI) would increase ischemic brain damage by a blood flow-mediated mechanism was investigated. Adult C57B1/6J mice were pretreated with either subcutaneous ICI (100 microg/day) or oil/ethanol vehicle for 1 week before 2 hours of middle cerebral artery occlusion (MCAO) and 22 hours of reperfusion. End-ischemic regional CBF was evaluated in additional cohorts using [14C]iodoantipyrine autoradiography. Infarction volume as measured by cresyl violet histology was greater in the striatum of ICI-treated females (70 +/- 3% of contralateral striatum vs. 40 +/- 12% in vehicle-treated females). Cortical injury was not enhanced relative to control animals (39 +/- 6% of contralateral cortex in ICI group vs. 27 +/- 8% in vehicle-treated group). Physiologic variables and ischemic reduction of the ipsilateral cortical laser-Doppler flow signal were similar between groups. Further, ICI treatment did not alter end-ischemic cortical or striatal CBF. The deleterious effect of ICI was limited to females, as there were no differences in stroke damage or CBF between male treatment groups. These data suggest that estrogen inhibits ischemic brain injury in striatum of the female by receptor-mediated mechanisms that are not linked to preservation of intraischemic CBF.
Fixed-tuned submillimeter wavelength waveguide mixers using planar Schottky-barrier diodes (1997)

The design, construction, and evaluation of fixed-tuned submillimeter wavelength waveguide mixers using planar Schottky diodes are presented in this paper. Electromagnetic fields within the planar diode package were analyzed using the finite-element method (FEM). Mixers using the University of Virginia SCIT5 planar diode were designed at both 585 and 690 GHz. A double sideband (DSB) system noise temperature of 2380 K was measured at 585 GHz using 1.16 mW of local oscillator (LO) power, and a system noise temperature of 2970 K DSB was measured at 690 GHz using 1.04 mW of LO power. In addition, the 585 GHz mixer was cooled to both 77 K and 4.2 K, with measured system noise temperatures of 1240 and 880-K DSB using LO powers of 0.47 and 0.14 mW, respectively. The modeling techniques were found to predict the measured conversion loss to within 1 dB. The performance of planar diode mixers is now within a factor of 1.5 of the best whisker-contacted Schottky diode mixers in this frequency range.
Artificial Intelligence in Finance & Investing: State-of-the-Art Technologies for Securities Selection and Portfolio Management (1995)

From the Publisher:
In Artificial Intelligence in Finance and Investing, authors Robert Trippi and Jae Lee explain this fascinating new technology in terms that portfolio managers, institutional investors, investment analysis, and information systems professionals can understand. Using real-life examples and a practical approach, this rare and readable volume discusses the entire field of artificial intelligence of relevance to investing, so that readers can realize the benefits and evaluate the features of existing or proposed systems, and ultimately construct their own systems. Topics include using Expert Systems for Asset Allocation, Timing Decisions, Pattern Recognition, and Risk Assessment; overview of Popular Knowledge-Based Systems; construction of Synergistic Rule Bases for Securities Selection; incorporating the Markowitz Portfolio Optimization Model into Knowledge-Based Systems; Bayesian Theory and Fuzzy Logic System Components; Machine Learning in Portfolio Selection and Investment Timing, including Pattern-Based Learning and Fenetic Algorithms; and Neural Network-Based Systems. To illustrate the concepts presented in the book, the authors conclude with a valuable practice session and analysis of a typical knowledge-based system for investment management, K-FOLIO. For those who want to stay on the cutting edge of the application revolution, Artificial Intelligence in Finance and Investing offers a pragmatic introduction to the use of knowledge-based systems in securities selection and portfolio management.
Experimental Model of Obstructive, Chronic Pancreatitis in Pigs (2003)

Ligation of the PD in pigs resulted in a marked fibrosing obstructive pancreatitis within 4 weeks, similar to human chronic pancreatitis in regard to clinical, functional, histological and biochemical parameters.
Infection with Francisella tularensis LVS clpB Leads to an Altered yet Protective Immune Response (2020)

ABSTRACT Bacterial attenuation is typically thought of as reduced bacterial growth in the presence of constant immune pressure. Infection with Francisella tularensis elicits innate and adaptive immune responses. Several in vivo screens have identified F. tularensis genes necessary for virulence. Many of these mutations render F. tularensis defective for intracellular growth. However, some mutations have no impact on intracellular growth, leading us to hypothesize that these F. tularensis mutants are attenuated because they induce an altered host immune response. We were particularly interested in the F. tularensis LVS (live vaccine strain) clpB (FTL_0094) mutant because this strain was attenuated in pneumonic tularemia yet induced a protective immune response. The attenuation of LVS clpB was not due to an intracellular growth defect, as LVS clpB grew similarly to LVS in primary bone marrow-derived macrophages and a variety of cell lines. We therefore determined whether LVS clpB induced an altered immune response compared to that induced by LVS in vivo . We found that LVS clpB induced proinflammatory cytokine production in the lung early after infection, a process not observed during LVS infection. LVS clpB provoked a robust adaptive immune response similar in magnitude to that provoked by LVS but with increased gamma interferon (IFN-γ) and interleukin-17A (IL-17A) production, as measured by mean fluorescence intensity. Altogether, our results indicate that LVS clpB is attenuated due to altered host immunity and not an intrinsic growth defect. These results also indicate that disruption of a nonessential gene(s) that is involved in bacterial immune evasion, like F. tularensis clpB , can serve as a model for the rational design of attenuated vaccines.
Thermal effects of lasers on dental tissues (1987)

Abstract The thermal effects of Nd:YAG, argon, and CO 2 laser beams are observed on enamel, dentin, and dental pulp by means of computerized infrared thermography and thermocouple. This study shows that the Nd:YAG laser beam deeply diffuses through the enamel and dentin to the pulp. The argon laser effects are inconsistent depending on whether the enamel surface is cleaned, but after cleaning, the superficial and deep temperatures are low. With the CO 2 laser, the enamel and dentin surfaces reach very high temperatures, but only low temperatures are measured in the pulp chamber.
Arbitrary tilings of the time-frequency plane using local bases (1999)

We show how to design filters given a prescribed tiling of the time-frequency plane. Moreover, we impose on these filters the structure of local orthogonal bases. These bases were recently constructed as a generalization of the cosine-modulated filter banks in discrete time and local trigonometric bases in continuous time. They have been found to be of considerable practical importance due to their simplicity (all filters are obtained from a single prototype) and low computational complexity. We show examples of design, in particular, that of a critical-band system for use in audio coding.
Effect of cellular repressor of E1A stimulated genes (CREG1) on cardiac function injury induced by angiotensin II in mice (2015)

Objective　To investigate the effect of cellular repressor of E1A stimulated genes (CREG1) on cardiac function in mouse with myocardial fibrosis. Methods　CREG1 knockout mice (CREG1+/–) and CREG1 wild-type mice (CREG1+/+) were used to reproduce the model of myocardial fibrosis by subcutaneous pump burying of angiotensin Ⅱ (AngⅡ). After being stimulated with AngⅡ for 14 days, myocardial fibrosis was verified by HE staining and Masson trichrome staining. Western blotting and immunohistochemistry were used to detect the expression of CREG1 in myocardium before stimulation and 3, 7, 14 days after the AngⅡ stimulation. The cardiac function was evaluated by echocardiography after AngⅡ stimulation for 14 days. The CREG+/+ mice were given AngⅡ for 14 days, and at the same time recombinant CREG1 protein [respectively 15, 30, 60 and 300μg/(kg.d), intraperitoneal (IP) injections] (treatment group) and NaCl (control group) were administered for treatment, and then cardiac function and myocardiac apoptosis were examined. Results　Western blotting and immunohistochemistry showed that the expression of CREG1 in heart tissue was significantly lower in CREG+/– mice than in CREG+/+ mice (P<0.05). After AngⅡ stimulation for 3, 7 and 14 days, the expression of CREG1 in heart tissue declined significantly in both CREG+/- and CREG+/+ mice (P<0.05), especially in CREG+/- mice (P<0.01). With HE and Masson staining, it was also found that CREG1 deficiency aggravated myocardial fibrosis and cardiac function deterioration in response to AngⅡ stimulation (P<0.05). Conversely, exogenous infusion of recombinant CREG1 protein significantly inhibited the occurrence of myocardial apoptosis (P<0.05), thus ameliorated cardiac function (P<0.05). Conclusions　CREG1 deficiency may aggravate the deterioration of cardiac function in mouse with myocardial fibrosis induced by AngⅡ stimulation. The deterioration of cardiac function can be improved by administration of exogenous recombinant CREG1 protein.
		
		DOI: 10.11855/j.issn.0577-7402.2015.01.04
Developmental regulation of spine motility in the mammalian central nervous system (1999)

The function of dendritic spines, postsynaptic sites of excitatory input in the mammalian central nervous system (CNS), is still not well understood. Although changes in spine morphology may mediate synaptic plasticity, the extent of basal spine motility and its regulation and function remains controversial. We investigated spine motility in three principal neurons of the mouse CNS: cerebellar Purkinje cells, and cortical and hippocampal pyramidal neurons. Motility was assayed with time-lapse imaging by using two-photon microscopy of green fluorescent protein-labeled neurons in acute and cultured slices. In all three cell types, dendritic protrusions (filopodia and spines) were highly dynamic, exhibiting a diversity of morphological rearrangements over short (<1-min) time courses. The incidence of spine motility declined during postnatal maturation, but dynamic changes were still apparent in many spines in late-postnatal neurons. Although blockade or induction of neuronal activity did not affect spine motility, disruption of actin polymerization did. We hypothesize that this basal motility of dendritic protrusions is intrinsic to the neuron and underlies the heightened plasticity found in developing CNS.
Polarizability calculations on water, hydrogen, oxygen, and carbon dioxide (1973)

Based on the semiclassical model of damped oscillators, a procedure is developed for the calculation of the dispersion of refractive index, polarizability, and dielectric permeability, which are treated as complex quantities. Using experimental values of refractive indices and employing the frequencies of strong absorption bands, a least squares fit is used to determine oscillator strengths and damping factors. The absorption coefficient and the imaginary part of the refractive index are also calculated at the corresponding wavelengths. The procedure is applied for the cases of water, hydrogen, and oxygen in both the liquid and gaseous states and for gaseous carbon dioxide, and a good agreement is obtained between calculated and observed values of refractive indices. Results are also compared with those of previous calculations. Calculated absorption coefficients agree well with experimental values in the region of absorption bands. The calculated values of oscillator strengths and damping factors are discussed. The previously determined values for the polarizability extrapolated to infinite wavelength agree with the present results for the contribution of the electronic motion to the polarizability, this contribution being about the same for both the liquid and gaseous states of hydrogen, oxygen, and water. The value obtained in the present work for the polarizability of liquid water is about 2.8-fold greater than the results of previous calculations; most of the contribution is due to atomic and molecular motions. Onsager's theory is shown to yield the experimental value of the permanent dipole of water from the dielectric constant of liquid water when our result for the polarizability of liquid water is employed.
Trace-based and geostatistical inversion of 3-D seismic data for thin-sand delineation: An application in San Jorge Basin, Argentina (1999)

Argentina’s San Jorge Basin, which straddles the southern provinces of Chubut and Santa Cruz in the heart of Patagonia, has been producing hydrocarbons since 1907. The region currently accounts for 32% of the country’s production. The existence and early geologic evolution of the basin is due to the same rift process responsible for the opening of the Atlantic Ocean in early Jurassic times. Extensive direct faulting and local erosion accompanied the rift evolution, thereby facilitating the accumulation of chiefly nonmarine terrigenous sediments well into the early Cretaceous. At this point, Andean tectonism became a major source of pyroclastic concentration in the sedimentary column; it was also responsible for pervasive batholitic intrusions. Clastic deposition in the hydrocarbon-producing zone is characterized by thick shale laminations of lacustrine and floodplain origin, interspersed with much thinner and laterally sparse sand bodies (the hydrocarbon reservoirs).
Treatment of Nasal Obstruction From Nasal Valve Collapse with Alar Batten Grafts (2003)

Nasal obstruction may require treatment with rhinoplasty techniques. One cause of nasal obstruction is known as nasal valve collapse. This refers to narrowness and weakness at the nasal valve, the narrowest part of the nasal airway. There are a number of surgical approaches available to treat nasal valve collapse. Selection of the appropriate surgical intervention depends on proper identification of the anatomic cause of the collapse. Alar batten grafts are especially useful for addressing nasal valve collapse caused by a weak nasal sidewall. In this report, we review the senior author's experience with the use of alar batten grafts for nasal valve collapse. Twenty-one patients had septoplasty with placement of alar batten grafts; all patients noted improvement in their nasal breathing. Seven patients underwent ear cartilage harvest with alar batten grafts, and five of them noted improvement, one noted partial improvement, one noted no improvement. Six patients underwent revision septorhinoplasty with alar batten grafting, and ten patients underwent revision septorhinoplasty with ear cartilage harvest and alar batten grafting. These patients all reported improvement in their nasal breathing postoperatively. Six patients underwent revision rhinoplasty (no septoplasty) with ear cartilage and battens. These patients hold special interest because no other intranasal procedures were performed that affected nasal breathing. All six of these patients reported significant improvement of their nasal breathing and all patients were satisfied with their postsurgical cosmetic appearance. The nasal valve area is considered to be the location of the least cross-sectional area in the nose. When narrowing of the nasal valve is a result of collapse of the nasal sidewall, alar batten grafts are a useful technique to address the patient's nasal obstruction.
Overexpression of N-Acetylglucosaminyltransferase III Enhances the Epidermal Growth Factor-induced Phosphorylation of ERK in HeLaS3 Cells by Up-regulation of the Internalization Rate of the Receptors (2001)

N-Acetylglucosaminyltransferase III (GnT-III) is a key enzyme that inhibits the extension of N-glycans by introducing a bisecting N-acetylglucosamine residue. In this study we investigated the effect of GnT-III on epidermal growth factor (EGF) signaling in HeLaS3 cells. Although the binding of EGF to the epidermal growth factor receptor (EGFR) was decreased in GnT-III transfectants to a level of about 60% of control cells, the EGF-induced activation of extracellular signal-regulated kinase (ERK) in GnT-III transfectants was enhanced to approximately 1.4-fold that of the control cells. A binding analysis revealed that only low affinity binding of EGF was decreased in the GnT-III transfectants, whereas high affinity binding, which is considered to be responsible for the downstream signaling, was not altered. EGF-induced autophosphorylation and dimerization of the EGFR in the GnT-III transfectants were the same levels as found in the controls. The internalization rate of EGFR was, however, enhanced in the GnT-III transfectants as judged by the uptake of (125)I-EGF and Oregon Green-labeled EGF. When the EGFR internalization was delayed by dansylcadaverine, the up-regulation of ERK phosphorylation in GnT-III transfectants was completely suppressed to the same level as control cells. These results suggest that GnT-III overexpression in HeLaS3 cells resulted in an enhancement of EGF-induced ERK phosphorylation at least in part by the up-regulation of the endocytosis of EGFR.
Working Toward Homogeneous Diesel Combustion: A Fresh Look at the Work of Max Fiedler (2001)

Abstract Max Fiedler developed a lightweight automotive diesel engine with a novel combustion system, presenting initial results in 1939. A unique injection concept incorporated in the engine created a pre-mixed, semi-homogeneous charge using uniformly low injection pressures and advanced injection timing. His evidence showed: extremely smooth combustion and controlled energy release in the early stages of burning; complete elimination of diesel knock; appropriate timing of the onset of combustion; and a combustion event that remained robust through to its conclusion, likely forming a minimum of particulate. Fiedler’s work was largely ignored by other engineers of the day, but there is significant evidence in later work that both explains and confirms his basic claims. The available knowledge relating to Fiedler’s combustion system provides important information about the conditions required to produce smooth heat release in well mixed compression ignition systems.
3-Alkylamino-4<i>H</i>-pyrido[2,3-<i>e</i>]-1,2,4-thiadiazine 1,1-Dioxides Structurally Related to Diazoxide and Pinacidil as Potassium Channel Openers Acting on Vascular Smooth Muscle Cells:  Design, Synthesis, and Pharmacological Evaluation (2000)

A series of 3-alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxides structurally related to diazoxide and pinacidil were synthesized and tested as possible K(ATP) channel openers on isolated pancreatic endocrine tissue as well as on isolated vascular, intestinal, and uterine smooth muscle. In contrast to previously described 3-alkylamino-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1, 1-dioxides, most of the new compounds were found to be poorly active on B-cells but exhibited clear vasorelaxant properties. 3-(3, 3-Dimethyl-2-butylamino)-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxide (4d) and 7-chloro-3-(3, 3-dimethyl-2-butylamino)-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxide (5d), two compounds bearing the alkyl side chain of pinacidil, were found to be the most active representatives of their respective series on rat aorta rings. 3-Cycloalkylalkylamino- and 3-aralkylamino-7-chloro-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxides also expressed myorelaxant activity on electrically stimulated guinea pig ileum and on oxytocin-induced contractions of the rat uterus. Further biological investigations ((86)Rb efflux measurements, vasodilator potency on 30 and 80 mM KCl-induced contractions in the absence and presence of glibenclamide) revealed that compounds 4d and 5d, but not compound 5f, expressed the pharmacological profile of classical K(ATP) channel openers. In conclusion, by changing the position of the nitrogen atom in the pyridine ring, we now have obtained a family of drugs expressing an opposite tissue selectivity. Taken as a whole, the present findings also suggest that 3-alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1, 1-dioxides such as 4c, 4d, 5c, and 5d may be considered as new examples of K(ATP) channel openers expressing a pharmacological profile similar to that of pinacidil and diazoxide.