gebhart/patrepeval huggingface dataset:
A context-aware system based on service-oriented architecture (2006)

Advances in mobile devices, sensors and wireless networks have motivated the development of context-aware applications. Such mobile applications use sensors for monitoring several features such as: location, temperature, velocity, weather, traffic jam, noise, air pollution, and so on. This monitoring enables service provision according to a given context. These applications are known as context-aware systems. Context-aware applications are sensible to user necessities, personalized according to his profile, requirements and context. They evaluate user environment and push information that is relevant to user context. In this paper we present Omnipresent, which is a service-oriented architecture for context-aware applications. Omnipresent may be accessed from either mobile devices or Web browsers, and it is based on Web services and well-established standards for LBS applications such as those proposed by the OpenGeoSpatial Consortium. Omnipresent offers several services: map presentation, routing, advertisement, and also works as a reminder tool.
Regioselective Copper-Catalyzed Boracarboxylation of Vinyl Arenes (2016)

Regioselective copper-catalyzed boracarboxylation of vinyl arenes with bis(pinacolato)diboron and carbon dioxide has been achieved. New boron-functionalized α-aryl carboxylic acids, including nonsteroidal anti-inflammatory drugs (NSAIDs), are obtained in moderate to excellent yields. The synthetic utility of the transformation was shown through subsequent derivatization of the carbon-boron bond yielding formal hydroxy- and fluorocarboxylation products as well as anionic difluoroboralactones.
Atomic Positional Versus Electronic Order in Semiconducting ZnSe Nanoparticles (2009)

Size-controlled ZnSe nanoparticles with high extents of atomic positional order are shown to exhibit large size-dependent variations in their local electronic environments. Solid-state ;{77}Se and ;{67}Zn NMR spectra reveal increasingly broad distributions of ;{77}Se and ;{67}Zn environments with decreasing nanoparticle sizes, in contrast with high degrees of atomic positional order established by transmission electron microscopy and x-ray diffraction. First-principles calculations of NMR parameters distinguish between atomic positional and electronic disorder that propagate from the nanoparticle surfaces and yield insights on the order and disorder present.
51. Oxidations with phenyl iodosoacetate. Part VI. The oxidation of some phenols containing electron-attracting substituents (1957)

A. R. Fox and K. H. Pausacker, J. Chem. Soc., 1957, 295 DOI: 10.1039/JR9570000295
Application of full chip OPC to quarter micron logic device (2003)

Model based full chip Optical Proximity Correction (OPC) was applied to logic devices with a minimum gate length of 0.24 /spl mu/m. Two empirical models were used in order to correct for both the 1D optical proximity effect and the 2D optical proximity effect simultaneously. OPC features such as line bias and hammer head were effective in reducing critical dimension variation and line shortening. Increased process margin and reduction in interconnection resistance were obtained.
Commercial Production and Development (2018)

Development of production technology, distribution, and sales of entomopathogenic nematode-containing products is occurring at a rapid pace. The strategies of commercial development which are selected will have a significant effect on how production technology develops and on which technologies are eventually implemented. The venture model can be successful when proprietary technologies can be developed in a relatively short time and when market development is possible in an equivalent time period. Existing technologies for the production of entomopathogenic nematodes have developed over a period of 60 years. The large-scale production of entomopathogenic nematode-containing products must be planned in a context composed of the production plant, distribution system, and application environment if the production system is to be profitable and self-sustaining. Economies of quality are expected because the nematodes would be produced in a homogeneous and reproducible environment. Economies of scale are cost decreases which result from increasing scale of operation and derive from three sources: capital, labor, and materials.
Proceedings in Synthetic Chemistry of Sialo-Glycoside (2004)

シアル酸のα-グリコシドの化学合成は、シアル酸の構造的な特徴である3-デオキシ構造とアノメリック炭素に結合したカルボキシル基の影響により、非常に難度が高い。本総説では、その合成上の難点を克服するためにシアル酸の化学が歩んだ歴史を概観するとともに、最近報告された新しいシアル酸供与体であるN-Trocシアル酸誘導体について取り上げる。
Design of Selective G-quadruplex Ligands as Potential Anticancer Agents (2008)

G-quadruplex structures are promising targets for design of cancer drugs with high selectivity and low toxicity. This review provides an update of the progress made over the last few years in the design of selective G-quadruplex ligands, and a comprehensive summary of the major design strategies and structural characteristics.
SAR Models for Estimating the Percutaneous Absorption of Polynuclear Aromatic Hydrocarbons (1998)

A structure-activity relationship (SAR) of the in vitro percutaneous absorption of polycyclic aromatic hydrocarbons (PAH) is described. The data set consisted of 60 three to seven ring PAH. Over 50 numeric descriptors were generated from the modeled molecular structures. Computer aided methods were used to evaluate descriptors and develop linear expressions relating the percent of dermally applied PAH dose absorbed through skin (PADA) to PAH structure. Three regression models with one and two variables were developed. The log octanol/water partition coefficient (log P) was the most important variable in determining percutaneous absorption. An inverse relationship between log P and the skin penetration properties of the PAH was observed. Nearly 40 of 60 PAH tested had PADA-values within a factor of two of benzo[a]pyrene (BaP); well over 50 of 60 had PADA-values within a factor of three. The results lend support to the use of isotopically labeled BaP as a surrogate for measuring the dermal flux (in vivo and in vitro) and estimating the dermal bioavailability of PAH from complex mineral oil and coal-tar derived mixtures.
Clinical Specificity of the Enzyme Immunoassay Test for Coccidioidomycosis Varies According to the Reason for Its Performance (2012)

The diagnosis of coccidioidomycosis relies heavily on serologic test results in addition to clinical history, physical examination, and radiographic findings. Use of the enzyme immunoassay (EIA) has increased because it is rapidly performed and does not require referral to a reference laboratory, as do complement fixation and immunodiffusion tests. However, interpretation of immunoglobulin M (IgM) reactivity by EIA in the absence of immunoglobulin G (IgG) reactivity has been problematic. We conducted a retrospective medical record review of all patients with such IgM reactivity at our institution to identify situations where the finding was more likely to be clinically specific for coccidioidal infection. From 1 January 2004 through 31 December 2008, a total of 1,117 patients had positive EIA coccidioidal serology or EIA IgM-only reactivity; of these, 102 patients (9%) had EIA IgM-only reactivity. Among the 102 patients with EIA IgM-only reactivity, 60 were tested to evaluate symptomatic illness, 13 for follow-up of previously abnormal serology, and 29 for screening purposes. Of the 102 patients, 80 (78%) had positive serologic findings by other methods or had positive culture or histology. Fifty-four (90%) of the 60 patients whose serology was performed to evaluate symptomatic illness had coccidioidal infection, whereas 13 (45%) of 29 patients whose serology was performed for screening purposes had coccidioidal infection. Of the 102 patients with isolated IgM reactivity by EIA, 12 later seroconverted to IgG and IgM reactivity. The use of EIA for screening in 29 asymptomatic persons was associated with unconfirmable results in 13 (45%). Although the majority of patients in our study with isolated IgM reactivity by EIA had probable or confirmed coccidioidomycosis, this result must be interpreted with caution for asymptomatic patients.
Isolation of a polyamine transport deficient cell line from the human non-small cell lung carcinoma line NCI H157 (1996)

In an effort to study the mechanism underlying the observed phenotype-specific response of human lung cancer cell lines to a polyamine analogue, N1,N12-bis(ethyl)spermine(BESpm), we have isolated a BESpm resistant cell line from the BESpm-sensitive large cell lung carcinoma line NCI H157. The mutant line exhibits identical growth rates in the presence or absence of the analogue. However, the overall growth of mutant cells reaches stationary phase earlier than that of the parental cells. In contrast to the parental cells, where a superinduction of spermidine/spermine N1-acetyltransferase (SSAT) is associated with BESpm toxicity, treatment of this resistant line with BESpm did not induce SSAT mRNA or enzyme activity. BESpm treatment was not effective in depleting the intracellular polyamine pools and very low intracellular BESpm levels were detected. This BESpm resistance is not mediated by multidrug resistance (MDR) protein, since these cells maintain their sensitivity to the antineoplastic agent adriamycin. Treatment of these cells with methylglyoxal bis(guanylhydrazone) (MGBG), an AdoMetDC inhibitor which enters cell using polyamine transport system, shows no inhibition of cell growth. Our data suggest that these mutant cells are deficient in polyamine transport. Consistent with this hypothesis, exogenous polyamines did not prevent difluoromethylornithine (DFMO) induced growth inhibition in the mutant cells.
A SIMD programming model for dart, javascript,and other dynamically typed scripting languages (2014)

It has not been possible to take advantage of the SIMD co-processors available in all x86 and most ARM processors shipping today in dynamically typed scripting languages. Web browsers have become a mainstream platform to deliver large and complex applications with feature sets and performance comparable to native applications, programmers must choose between Dart and JavaScript when writing web programs. This paper introduces an explicit SIMD programming model for Dart and JavaScript, we show that it can be compiled to efficient x86/SSE or ARM/Neon code by both Dart and JavaScript virtual machines achieving a 300%-600% speed increase across a variety of benchmarks. The result of this work is that more sophisticated and performant applications can be built to run in web browsers. The ideas introduced in this paper can also be used in other dynamically typed scripting languages to provide a similarly performant interface to SIMD co-processors.
Thomson Legal and Regulatory at NTCIR-4: Monolingual and Pivot-Language Retrieval Experiments (2004)

Thomson Legal and Regulatory participated in the CLIR task of the NTCIR-4 workshop. We submitted formal runs for monolingual retrieval in Japanese, Chinese and Korean. Our bilingual runs from Chinese and Korean to Japanese rely on English as a pivot lan- guage. During our monolingual experiments, we compared building stopword lists using query logs to building stopword lists from collection statistics with further manual editing. We investigated decompounding for Korean, more precisely partial credit of compound parts. Finally we incorporated pseudo-relevance feed- back in our Japanese runs. Our bilingual approach was an experiment to con- struct a system within a short timeframe using publi- cally available resources. The low quality of retrieval suggests that such an approach is not viable in a real environment.
Combined microseismic and 4D to calibrate and confirm surface 3D azimuthal AVO/LMR predictions of completions performance and well production in the Horn River gas shales of NEBC (2012)

The ability to high-grade gas shales is essential to optimizing completions and maximizing stimulated rock volume (SRV) in the capital-intensive development of the Horn River resource play in northeast British Columbia (NEBC). To assist in optimizing stimulation efforts, seismic data are used to estimate and map four parameters that influence hydraulic fracture effectiveness: rock properties, in-situ stress, natural fractures, and reservoir geometry.
Optical Design Methods, Applications and Large Optics (1985)

This book contains the papers presented at a conference on optics. Topics covered are Calculation and optimization methods; Optical design software; Infrared optics; Diagnosis and tolerancing; Image formation: special aspects; Lens Design; and Large optics. The papers include; Mirror substrate fabrication techniques of low expansion glasses; REOSC technology for the manufacture and testing of very large mirrors; and On-line interferometric mirror deforming measurement with a high power argon ion laser.
Effect of strain on the critical parameters of V2(Hf, Zr) Laves phase composite superconductors (1982)

Strain effects on the critical parameters of composite-processed V2(Hf, Zr) Laves phase superconductors have been examined. The critical temperature is found to be insensitive to the strain induced by the thermal differential contraction between the composite components. Critical current versus uniaxial strain curves obtained are completely flat at magnetic fields up to 19 T. It also turns out that the bulk upper critical field shows essentially no sensitivity to uniaxial strain. These results, which are quite different from those reported for A15 compound superconductors, are discussed in terms of the structural insensitivity of the Laves phase superconductor. Fractography suggests that the mechanical properties of V2(Hf, Zr) composite conductors may be improved by the grain refinement of component alloys.
Reactivity and Applications of New Amine Reactive Cross-Linkers for Mass Spectrometric Detection of Protein−Protein Complexes (2009)

Chemical cross-linking of proteins permits the stabilization of noncovalent complexes through introduction of covalent bonds. A crucial challenge is to find the fastest and most efficient cross-linkers in order to minimize reaction times and to handle delicate complexes. New cross-linkers were synthesized by introducing N-hydroxyphthalimide, hydroxybenzotriazole, and 1-hydroxy-7-azabenzotriazole as leaving groups instead of the commonly used N-hydroxysuccimidyl moiety. With the use of matrix-assisted laser desorption ionization (MALDI) mass spectrometry, these new cross-linkers were then compared with the commercially available disuccinimidyl suberate (DSS) for covalent stabilization of the gluthatione-S-transferase (GST) dimer and of an antibody-antigen complex. They showed a better efficiency, generated about 30% more cross-linked complex, and reacted about 10 times faster than DSS. The reaction with the GST dimer was utilized to get information about their reaction efficiency and kinetics. Their ability to stabilize only specific protein complexes was verified by incubating them with a mixture of the proteins GST and ubiquitin. Finally, the cross-linkers were incubated with synthetic peptides to study the selectivity of the binding with various amino acid side chains. Not only lysine but also tyrosine was found to react with the newly synthesized cross-linker containing 1-hydroxy-7-azabenzotriazole as the reactive group.
The Role of Micropores Structure in Conductive and Convective Heat Transfer within Porous Media (2009)

The microstructure of porous media is basically characterized by the geometry of voids and the solid phase. The arrangement of discrete regions, if either the solid phase or voids can be considered as a discrete phase, will have great effects on conduction and convection transport of heat through the porous medium. The relation between the geometry and transport properties of a porous medium is scientifically and technologically important. In the present study, we have presented a numerical simulation in a two-dimensional geometry to ascertain the influence of microstructural characteristics on the transport properties of porous media composed of discrete phases. Heat transfer is simulated in a rectangular porous domain subjected to symmetry boundary conditions on two opposite lateral sides and two inlet and outlet boundaries on the other sides. The domain is composed of a number of discrete regions (objects) with elliptic and circular cross-sections that are arranged in either an ordered or a disordered fashion with given boundary conditions on the surface of the objects. Results lead us to some interesting features of conductive and convective heat transfer in porous media that are associated with the above-mentioned microstructural properties. The surface temperature of the discrete phase and the fluid temperature depend strongly on the Re and Nu numbers in convective flows. On the other hand, conductive heat transfer characteristics through the medium are significantly dependent on the ratio of the conductivities of both phases.
Operation of a Six-Mev Linear Electron Accelerator (1951)

The operation of a 6-Mev linear electron accelerator is described. It is of the traveling-wave type, 14 feet in length. A single magnetron is used as a power source, operating at a wavelength of 10.5 cm, with a peak power output of 0.9 megawatt. Electrons are injected at a velocity v=c/2. Approximately 1/20 of the injected electrons reach the target end of the accelerator, with energies falling in a 1-Mev range near 6 Mev. The average current obtained is 0.05 μa. With an electron pulse length of 0.8 μsec and a pulse repetition rate of 60 per sec, this corresponds to a peak current of the order of 1 ma.
209. Spectroscopic studies on alkyl and hydrido transition metal carbonyls and π-cyclopentadienyl carbonyls (1963)

A. Davison, J. A. McCleverty and G. Wilkinson, J. Chem. Soc., 1963, 1133 DOI: 10.1039/JR9630001133
Thermal decomposition of a fullerene mix (1995)

Experiments to characterize fullerene decomposition at temperatures above 973 K were conducted by spectroscopic analysis of samples heated in vacuo. The thermal decomposition can be described by first-order kinetics with an activation energy of 266\ifmmode\pm\else\textpm\fi{}9 kJ/mol and a preexponential factor of 1.24\ifmmode\times\else\texttimes\fi{}${10}^{9}$ ${\mathrm{s}}^{\mathrm{\ensuremath{-}}1}$. Though scanning electron micrographs display structures with a distinctly faceted appearance, x-ray diffraction, Raman spectroscopy, and transmission-electron microscopy all show that the material is composed of amorphous carbon and graphite, indicating that pyrolysis of the fullerite occurs without destroying crystal facets.
Polyalkylene sulfides. VI. New polymers capable of cross‐linking (1951)

Abstract The formation of polymers from diolefins and dimercaptans has been extended to some new monomer combinations to yield strong, slightly elastic fibrous polymers which contain groups that permit subsequent cross‐linking. Osmotic molecular weight data have been obtained on a variety of polymers with different inherent viscosities. Polymers with a molecular weight of 60,000 have been obtained from biallyl and hexamethylenedithiol. Diallyl sulfide has been found to be relatively unreactive toward the addition of a mercaptan under the conditions used. This indicates that a sulfur atom beta to the double bond interferes with the free radical‐catalyzed addition of a mercaptan. The basecatalyzed reaction of hexamethylenedithiol and the cross‐conjugated dienone, dibenzalacetone, has yielded a rubbery‐type polymer.
Integrative orthodontics with the ribbon arch. (2004)

The ribbon arch had great popularity and utility early in the 20th century, but lost its appeal as edgewise techniques developed. Some clinicians have made attempts to revive the procedure, but they have relied upon costly changes in bracket and band inventories and have not yet received extensive endorsement. A newer approach that relies only upon the use of newly developed titanium and stainless steel ribbon archwires offers orthodontists a simplified and inexpensive method for assimilating this helpful method. Such wires allow orthodontists to create an integrative therapeutic protocol that combines much of the alignment, leveling, and torque control in a single wire.
Structure and function of enzymes in heme biosynthesis (2010)

Tetrapyrroles like hemes, chlorophylls, and cobalamin are complex macrocycles which play essential roles in almost all living organisms. Heme serves as prosthetic group of many proteins involved in fundamental biological processes like respiration, photosynthesis, and the metabolism and transport of oxygen. Further, enzymes such as catalases, peroxidases, or cytochromes P450 rely on heme as essential cofactors. Heme is synthesized in most organisms via a highly conserved biosynthetic route. In humans, defects in heme biosynthesis lead to severe metabolic disorders called porphyrias. The elucidation of the 3D structures for all heme biosynthetic enzymes over the last decade provided new insights into their function and elucidated the structural basis of many known diseases. In terms of structure and function several rather unique proteins were revealed such as the V-shaped glutamyl-tRNA reductase, the dipyrromethane cofactor containing porphobilinogen deaminase, or the "Radical SAM enzyme" coproporphyrinogen III dehydrogenase. This review summarizes the current understanding of the structure-function relationship for all heme biosynthetic enzymes and their potential interactions in the cell.
Lipopolysaccharide recognition protein, MD‐2, facilitates cellular uptake of <i>E. coli</i>‐derived plasmid DNA in synovium (2005)

Our data support a physical association between LPS and E. coli-derived plasmid DNA, and that in vivo transfection of fibroblast-like synoviocytes is dependent on the soluble form of the LPS-binding protein MD-2.
The Mechanism of Water Exchange in AmO<sub>2</sub>(H<sub>2</sub>O)<sub>5</sub><sup>2+</sup> and in the Isoelectronic UO<sub>2</sub>(H<sub>2</sub>O)<sub>5</sub><sup>+</sup> and NpO<sub>2</sub>(H<sub>2</sub>O)<sub>5</sub><sup>2+</sup> Complexes as Studied by Quantum Chemical Methods (2004)

The water exchange mechanism for AmO2(H2O)52+ and the isoelectronic UO2(H2O)5+ and NpO2(H2O)52+ ions has been investigated using quantum chemical methods and compared to previous findings in the uranyl(VI) system (Vallet, V. et al. J. Am. Chem. Soc. 2001, 123, 11999). There are substantial and predictable changes in the geometry and preferred exchange pathways between uranyl(V) and the different actinyl(VI) complexes. The smaller charge on the uranyl(V) center makes the dissociative pathway more favorable than the associative/interchange pathways in the actinyl(VI) systems.
Pacemaker Electrocardiography of Rate Smoothing During DDD Pacing (1985)

A rate smoothing option is available in a new bipolar AV universal (DDD) pacemaker. In three patients, two with intact retrograde conduction and one with retrograde block, rate smoothing values of 3% and 6% were programmed. Irregular pacemaker-mediated tachycardia occurred in one patient and AV synchrony was temporarily lost in the other two patients. In this report, we describe the pacemaker electrocardiography of rate smoothing during DDD pacing.
Numerical Evaluation of a Two-Loop Diagram in the Cutoff Regularization (2003)

The sunset diagram of $\lambda\phi^4$ theory is evaluated numerically in cutoff scheme and a nonzero finite term (in accordance with dimensional regularization (DR) result) is found in contrast to published calculations. This finding dramatically reduces the critical couplings for symmetry breaking in the two loop effective potential discussed in our previous work.