gebhart/patrepeval huggingface dataset:
Capacitive micromachined ultrasound transducer (cMUT) for immunosensor design (2010)

An affinity sensor based on a capacitive micromachined ultrasound transducer (cMUT) is reported by this Communication. The cMUT micromembrane arrays modified with adsorbed bovine leukemia virus protein gp51 were applied as a biological recognition part. The cMUT-based sensor is shown to be sensitive to the antibodies against bovine leukemia virus protein gp51 (anti-gp51). Two different concentrations of anti-gp51-containing samples and one blank sample without anti-gp51 were tested. The sensitivity of cMUT-based immunosensor is comparable with the sensitivity of a quartz microbalance-based immunosensor. The cMUT array provides a multi-channel system for the measurement of analytical signal. Moreover, two different characteristics--the resonance frequency shift (Deltaf) and the shift of the real part of the electromechanical impedance (DeltaRe)--could have been evaluated simultaneously. Both analytical signals are informative and can be applied for the estimation of immune complex formation. We found the performance of such a system being potentially superior over some other immunosensing techniques. It is more rapid than electrochemical techniques and provides two different informative parameters.
Associação da concentração do lactato plasmático após exercício resistido e pressão intraocular. (2013)

This study examined the association of plasma lactate concentrations with changes in i n t r a o c u l a r p r e s s u r e ( I O P ) a f t e r r e s i s t a ...
A Dynamometer on Which the Dynamic Behaviour of a Passenger Car can be Simulated (1972)

The development of a new stationary dynamometer is described, in which a passenger car is subjected to a system of forces and couples similar to that which it would experience on the roads. Speeds up to 200 km/h can be simulated. Tests on the dynamometer can be carried out in complete safety, and measurements made with an accuracy that would not be possible in tests on the road; indeed, measurements can be made on the rig which would be very difficult to make on a moving vehicle. Some of the possible applications of the dynamometer are discussed; it could, for example, be used for the study of braking, traction, steering, road holding, tyre behaviour, and deflection of headlight beams. Some of the work that has already been done is described. It is considered that dynamometers of this nature can make a great contribution to road safety.
Isolation and Structural Characterization of [P(AuPPh<sub>3</sub>)<sub>5</sub>][BF<sub>4</sub>]<sub>2</sub> via Cleavage of a P−P Bond by Cationic Gold Fragments:  Direct Evidence of the Structure of the Elusive Tetrakis[phosphineaurio(I)]phosphonium(+) Cation (1996)

The reaction of [(Ph3PAu)3O]BF4 with P2(SiMe3)4 in a 2:1 ratio results in cleavage of the P−P bond and formation of the pentacoordinate dication [P(AuPPh3)5]2+ in moderate yield. Low temperature 31P NMR studies indicate that the gold atoms are equivalent in solution. However, the solid state molecular structure of this homoleptic dication is square pyramidal rather than the classically expected trigonal bipyramid.
TMN pilot application functions (2005)

In recent years, the building blocks of modern telecom munication systems have become much more complew in structure and operation. At the same time their design is based on increasingly reliable components and an the availability of sophisticated communication networks like CCITT n. 7 and X25. As a consequence, the operation and maintenance of today's systems requires less but more highly qualified personnel, and many network operators are evolving towards the centralization and automation of O&M functions, following the internationally defined Telecommunication Management Network (TMN) that allows the introduction of now functions and the improvement of existing ones. This paper describes the following three pilot applications as defined by Alcatel:
High-Temperature Corrosion Rates of Several Metals with Hydrogen Sulfide and Sulfur Dioxide (1952)

The corrosion rates at temperatures above 1000°K were determined for several metals including copper, silver, Inconel, nickel, 18‐8 stainless steel, iron, tungsten, molybdenum, and tantalum in atmospheres of hydrogen sulfide, sulfur dioxide, and carbon monoxide. This was done by increase in electrical resistance of the metals in the form of filaments 0.010 inch in diameter. The metals most easily corroded in were Inconel, iron, copper, and stainless steel, whereas tungsten, molybdenum, and tantalum offered the most resistance. Inconel is very resistant to , whereas tungsten, tantalum, and molybdenum are easily corroded. Carbon monoxide increases the corrosion rate of nickel in hydrogen sulfide, whereas the corrosion rate of iron is decreased in the presence of carbon monoxide.
Total Synthesis of (−)-Histrionicotoxin 285A and (−)-Perhydrohistrionicotoxin (2008)

Starting from commercially available ( S)-glycidol, and via a common intermediate, the total synthesis of (-)-histrionicotoxin 285A and (-)-perhydrohistrionicotoxin has been achieved. Key to this synthesis was the efficient construction of a six-membered, chiral, cyclic nitrone.
A Combination of Electroencephalogram and Auditory Evoked Potentials Separates Different Levels of Anesthesia in Volunteers (2009)

In Brief BACKGROUND: It has been shown that the combination of electroencephalogram (EEG) and auditory evoked potentials (AEP) allows a good separation of consciousness from unconsciousness. In the present study, we sought a combined EEG/AEP indicator that allows both separation of consciousness from unconsciousness and discrimination among different levels of sedation and hypnosis over a wider range of anesthesia. METHODS: Fifteen unpremedicated volunteers received mono-anesthesia with sevoflurane or propofol in a randomized crossover design in two consecutive sessions. Loss of consciousness (LOC) and EEG burst suppression (BSP) defined end-points from the upper and lower range of general anesthesia. In addition to those two extremes, the difference between anesthetic concentration at BSP and LOC was divided into three equal intervals, resulting in two intermediate levels which divided the concentration from LOC (minimum) to BSP (maximum) into three equal steps. This data set was used to test whether a previously described combined EEG/AEP indicator “detector of consciousness” can also discriminate among degrees of anesthetic effects from the awake state to BSP. Furthermore, a new improved combined EEG/AEP indicator was developed on the basis of the data from the current study, and subsequently this new indicator was tested for its ability to separate consciousness from unconsciousness with the patient data set. RESULTS: The former “detector of consciousness” showed a prediction probability (PK) of 0.77 to separate different levels of anesthesia from the current study, whereas for the new combined EEG/AEP indicator, PK was 0.94. The new indicator was further applied to the previous study and achieved a PK of 0.89. CONCLUSIONS: These results show that with the new indicator presented here, a combination of EEG and AEP parameters can be used to differentiate degrees of anesthetic effects over a wide range of hypnosis, from the conscious state to deep anesthesia (i.e., BSP). IMPLICATIONS: Data from a volunteer study and a previous patient study were used to develop a new combined electroencephalogram/auditory evoked potentials parameter which can both discriminate between consciousness and unconsciousness and differentiate levels of hypnosis from awake to deep anesthesia.
UV-curing Behaviors and Mechanical Properties of UV-cured Polylactic Acid (PLA) (2013)

UV curing was introduced via a chemical treatment by adding small amounts of a hexafunctional acrylic monomer and a photoinitiator to improve the mechanical properties of PLA. This study also employed a semi-interpenetrated structured polymer network through the process of UV-curing. The UV curing behaviors were investigated using FTIR-ATR spectroscopy and gel fraction determination. Also, the tensile strength was investigated with different hexafunctional acrylic monomer contents and UV doses. The results showed that the crosslinking of UV-induced chemically treated PLA started at a low content of hexafunctional acrylic monomer, resulting in a significant improvement of the mechanical properties compared to those of neat PLA due to crosslinking.
The Politics of Non-Partisan Trade Unions: The British Case (1987)

We've got to be very careful regarding politics. You can't separate politics from our unionism but a lot of members don't look at it like that.



I would like affiliation to the Labour Party but half the members would resign.



I don't think it's any business of the union to get involved in politics.



Members Comments (IRSF, 1983).
Method for resolving simultaneous same-row access in Dual-Port 8T SRAM with asynchronous dual-clock operation (2013)

This work proposes a novel Dual-Port (DP) 8T SRAM operation scheme. The scheme improves the Read stability and Write-ability, and allows asynchronous operation with arbitrary clock timing skew between two ports. It facilitates high performance, low-power and low V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MIN</sub> with minimum device and area overhead. Post-simulation results show almost no timing penalty for simultaneous same-row access and the performance is almost the same as that for one port operation.
A Robust Time-Domain Beam Alignment Scheme for Multi-User Wideband mmWave Systems (2017)

Millimeter wave (mmWave) communication with large array gains is a key ingredient of next generation (5G) wireless networks. Effective communication in mmWaves usually depends on the knowledge of the channel. We refer to the problem of finding a narrow beam pair at the transmitter and at the receiver, yielding high Signal to Noise Ratio (SNR) as Beam Alignment (BA). Prior BA schemes typically considered deterministic channels, where the instantaneous channel coefficients are assumed to stay constant for a long time. In this paper, in contrast, we propose a time-domain BA scheme for wideband mmWave systems, where the channel is characterized by multi-path components, different delays, Angle-of-Arrivals/Angle-of-Departures (AoAs/AoDs), and Doppler shifts. In our proposed scheme, the Base Station (BS) probes the channel in the downlink by some sequences with good autocorrelation property (e.g., Pseudo-Noise (PN) sequences), letting each user estimate its best AoA-AoD that connects the user to the BS with two-sided high beamforming gain. We leverage the sparse nature of mmWaves in the AoA-AoD-time domain, and formulate the BA problem as a Compressed Sensing (CS) of a non-negative sparse vector. We use the recently developed Non-Negative Least Squares (NNLS) technique to efficiently find the strongest path connecting the BS and each user. Simulation results show that the proposed scheme outperforms its counterpart in terms of the training overhead and robustness to fast channel variations.
Reporter Concerns in 300 Mode-Related Incident Reports from NASA's Aviation Safety Reporting System (1996)

A model has been developed which represents prominent reporter concerns expressed in the narratives of 300 mode-related incident reports from NASA's Aviation Safety Reporting System (ASRS). The model objectively quantifies the structure of concerns which persist across situations and reporters. These concerns are described and illustrated using verbatim sentences from the original narratives. Report accession numbers are included with each sentence so that concerns can be traced back to the original reports. The results also include an inventory of mode names mentioned in the narratives, and a comparison of individual and joint concerns. The method is based on a proximity-weighted co-occurrence metric and object-oriented complexity reduction.
Genetic disruption of <i>Pten</i> in a novel mouse model of tomaculous neuropathy (2012)

'Tomacula' and myelin outfoldings are striking neuropathological features of a diverse group of inherited demyelinating neuropathies. Whereas the underlying genetic defects are well known, the molecular mechanisms of tomacula formation have remained obscure. We hypothesized that they are caused by uncontrolled, excessive myelin membrane growth, a process, which is regulated in normal development by neuregulin-1/ErbB2, PI3 Kinase signalling and ERK/MAPK signalling. Here, we demonstrate by targeted disruption of Pten in Schwann cells that hyperactivation of the endogenous PI3 Kinase pathway causes focal hypermyelination, myelin outfoldings and tomacula, even when induced in adult animals by tamoxifen, and is associated with progressive peripheral neuropathy. Activated AKT kinase is associated with PtdIns(3,4,5)P(3) at paranodal loops and Schmidt-Lanterman incisures. This striking myelin pathology, with features of human CMT type 4B1 and HNPP, is dependent on AKT/mTOR signalling, as evidenced by a significant amelioration of the pathology in mice treated with rapamycin. We suggest that regions of non-compact myelin are under lifelong protection by PTEN against abnormal membrane outgrowth, and that dysregulated phosphoinositide levels play a critical role in the pathology of tomaculous neuropathies.
Structure Function Analysis of Novel Type III Polyketide Synthases from Arabidopsis thaliana (2008)

The genome sequencing project revealed presence of two active chalcone synthase (CHS) homologues (At1g02050 and At4g34850) in the model plant Arabidopsis thaliana. We report herein the two genes encode closely related novel plant-specific type III polyketide synthases (PKSs) that produces long-chain alkyl alpha-pyrones. PKS-A (At1g02050) and PKS-B (At4g34850) share significantly low amino acid sequence identity (20-40%) with other type III PKSs, and the phylogenetic tree analysis revealed that they form a separate cluster located closely to those of bacterial type III PKSs. When expressed in Escherichia coli, both PKS-A and PKS-B accepted unusually long (up to the C(20) chain-length) fatty acyl CoAs as a starter substrate, and carried out sequential condensations with malonyl-CoA to produce triketide and tetraketide alpha-pyrones. Interestingly, despite the low sequence identity, homology modeling revealed that the active-site architecture of PKS-A and PKS-B showed similarity to that of a bacterial type III PKS from Mycobacterium tuberculosis.
Programmed grammars -- A new device for generating formal languages (1967)

A new form of grammar, which is called a programmed grammar, is defined and some of its properties are described. Programmed grammars are a generalization of phrase structure grammars where each production has a label, a core consisting of an ordinary phrase structure production, and two associated sets of production labels. If a production can be applied to an intermediate string in a derivation, it is applied as far to the left as possible, and the next production to be used is selected from the first set of labels. If the production cannot be applied to the intermediate string, the next production is selected from the other set of labels. The generative power of programmed grammars with various types of production cores is investigated. The additional machinery of programmed grammars does not add any additional generative power if the cores are arbitrary, context sensitive, linear, or one-sided linear. However, programmed grammars whose cores contain a single symbol on the lefthand side and an arbitrary string on the righthand side can generate all recursively enumerable languages. The class of languages generated by grammars of this type with the additional restriction that the righthand side of a production core cannot be the null string is properly contained with the context sensitive languages and properly contains the context free languages. For grammars of this type, called cfpg's, the emptiness and finiteness problems are undecidable. In addition every recursively enumerable language can be obtained from a cfpg language by a homomorphism. The subset of cfpg's for which the two sets of production labels are the same for each production is also considered. The class of languages generated by these grammars is properly contained within the cfpg languages and properly contains the context free languages. Furthermore, the emptiness problem is decidable for these grammars. This paper is an extended abstract based on the author's doctoral thesis.
Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis (2001)

These results indicate that Fkn and its receptor are both expressed in RA and in rat AIA, and that sFkn is up-regulated in RA SF. Furthermore, our data suggest a new role for Fkn in monocyte chemotaxis in the inflamed RA joint.
Competitive contagion in networks (2012)

We develop a game-theoretic framework for the study of competition between firms who have budgets to "seed" the initial adoption of their products by consumers located in a social network. The payoffs to the firms are the eventual number of adoptions of their product through a competitive stochastic diffusion process in the network. This framework yields a rich class of competitive strategies, which depend in subtle ways on the stochastic dynamics of adoption, the relative budgets of the players, and the underlying structure of the social network.
The Impact of Substance P on the Pathogenesis of Insulin Resistance Leading to Gestational Diabetes (2014)

Gestational diabetes mellitus is one of the most often medical conditions during pregnancy affecting 5-6% of all pregnancies. The etiology of gestational diabetes is not clearly understood. In obesity and diabetes mellitus type 2, abnormal insulin signaling is an important agent mediating the increase of insulin resistance. Insulin receptor substrate serine phosphorylation is a time-controlled physiological reaction in insulin signaling that has been disrupted by metabolic and inflammatory stresses to support insulin resistance. Several kinases, including inhibitor of nuclear factor ĸB kinase β (IKK β), c-Jun N-terminal kinase (JNK), mammalian target of rapamycin (mTOR), protein kinase C (PKC) and ribosomal S6 protein kinase (S6K), are activated by these stimulators of insulin resistance and phosphorylate insulin receptor substrate proteins on several serine residues in an uncontrollable method. There are an increasing number of data indicating that substance P, being one of the crucial activators of these kinases, is a potent cytokine that impairs insulin signaling. Here we discuss recent studies that expand our understanding of how substance P may contribute to the development of insulin resistance. In our opinion, there are many interesting data suggesting that substance P may be a new player in the pathogenesis of this unfavorable condition, leading not only to the development of diabetes mellitus type 2, but also gestational diabetes. Since the etiology of gestational diabetes remains unclear, there is a strong need to explore new directions, including those not directly associated with the canonical knowledge regarding this pathology.
Cell surface sialic acid and the invasive and metastatic potential of T-cell hybridomas. (1986)

T-cell hybridomas prepared by fusion of non-invasive non-metastatic BW5147 T-lymphoma cells and activated normal T-cells were found to be highly invasive in vitro and highly metastatic in vivo upon tail vein injection. By prolonged culturing and subcloning, non-invasive, non-metastatic hybrids were selected with modal DNA/cell contents close to the diploid value of both fusion partners. Since normal activated T-cells were invasive in vitro in hepatocyte cultures, these data suggest that invasiveness of the hybrids is derived from the parental normal T-cells and is one of the properties responsible for the metastatic potential of these cells. Analysis of a large panel of T-cell hybrids with fluorescein isothiocyanate conjugated lectins, specific for terminal galactose and/or N-acetylgalactosamine sugar residues, showed an inverse correlation between expression of lectin receptor sites and invasive and metastatic potential of the hybrids. Soybean agglutinin, as well as peanut agglutinin and Ricinus communis agglutinin, reacted strongly with non- or low-invasive hybrids but only weakly with invasive hybrids. The difference in lectin binding between both types of hybrids appeared to be due to masking of receptor sites by sialic acid. Removal of cell surface sialic acid by neuraminidase treatment unmasked the lectin receptor sites of invasive hybrids to the level of the corresponding sites of non- or low-invasive cells. This increase in active lectin binding sites was simultaneously accompanied by a striking decrease of invasiveness to the level of the low-invasive hybrids. Conversely, the blocking of R. communis agglutinin receptors by sialic acid allowed selection of invasive hybrids from segregating cell populations with the toxic lectin R. communis agglutinin. The results taken together indicate that sialylation of particular cell surface carbohydrate residues on the T-cell hybridomas is associated with the invasive and metastatic potential of these hybrids. The reduction of invasive potential after removal of cell surface sialic acid provides further evidence for a functional role of this sugar residue in invasiveness of the T-cell hybrids.
Research on Composition of Astragalus Polysaccharedes (2011)

Objective: To get a crude perception of the composition and the molecular weight of astragalus polysaccharedes(APS).Method: Using high performance gel permeation chromatograph(HPGPC) and alcohol fractionation,we got a better outline of the composition of the polysaccharides and respectively analized their molecular weights.Result: The test results proved that APS breaks down to two parts with respect to their ranges of molecular weight.Conclusion: The part with low molecular weight exhibits the character of pure substance which is exploitable.
Toward Dual-functional Radar-Communication Systems: Optimal Waveform Design (2018)

We focus on a dual-functional multi-input-multi-output (MIMO) radar-communication (RadCom) system, where a single transmitter with multiple antennas communicates with downlink cellular users and detects radar targets simultaneously. Several design criteria are considered for minimizing the downlink multiuser interference. First, we consider both omnidirectional and directional beampattern design problems, where the closed-form globally optimal solutions are obtained. Based on the derived waveforms, we further consider weighted optimizations targeting a flexible tradeoff between radar and communications performance and introduce low-complexity algorithms. Moreover, to address the more practical constant modulus waveform design problem, we propose a branch-and-bound algorithm that obtains a globally optimal solution, and derive its worst-case complexity as function of the maximum iteration number. Finally, we assess the effectiveness of the proposed waveform design approaches via numerical results.
A global illumination solution for general reflectance distributions (1991)

A general light transfer simulation algorithm for environments composed of materials with arbitrary reflectance functions is presented. This algorithm removes the previous practical restriction to ideal specular and/or ideal diffuse environments, and supports complex physically based reflectance distributions, This is accomplished by extending previous two-pass ray-casting radiosity approaches to handle non-uniform intensity distributions, and resolving all possible energy transfers between sample points. An implementation is described based on a spherical harmonic decomposition for encoding both bidirectional reflectance distribution functions for materials, and directional intensity distributions for illuminated surfaces. The method compares favorably with experimental measurements.