gebhart/patrepeval huggingface dataset:
Production of Perfluoroalkylated Nanospheres from Buckminsterfullerene (1993)

Perfluoroalkylated nanospheres have been prepared by reaction of fullerenes with a variety of fluoroalkyl radicals. The latter are generated by thermal or photochemical decomposition of fluoroalkyl iodides or fluorodiacyl peroxides. Up to 16 radicals add to C(60) to afford easily isolable fluoroalkylated derivatives. The monosubstituted radical adducts were detected by electron spin resonance in the early stages of the fluoroalkylation reactions. These spheroidal molecules are thermally quite stable, soluble in fluoroorganic solvents, chemically resistant to corrosive aqueous solutions, and more volatile than the parent fullerenes. Films of the sublimed material display properties typical for a perfluoroalkylated material.
Low-pressure measurement limits for silicon piezoresistive circular diaphragm sensors (1995)

The lower limit to a practical measurable span is investigated for pressure sensors that have a silicon diaphragm with circular shape and employ piezoresistive gages. Output voltages and non-linearities of the sensors are analysed, taking into account the effects of the diaphragm's large deflection and the piezoresistive effect non-linearities. Based on this analysis and industrial requirements (the minimum span output voltage must be larger than 4.3 mV V-1 and non-linearities must be within +or-0.2% at the same time), it is found that the minimum span is 15 kPa.
NHC-stabilized ruthenium nanoparticles as new catalysts for the hydrogenation of aromatics (2012)

The application of ruthenium nanoparticles (RuNPs) stabilized by the N-heterocyclic carbenes (NHC) N,N′-di(tert-butyl)imidazol-2-ylidene (ItBu) and 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene IPr as catalysts in the hydrogenation of several substrates is reported under various reaction conditions (solvent, substrate concentration, substrate/metal ratio, temperature). The RuNHC nanoparticles are active catalysts in the hydrogenation of aromatics and show an interesting ligand effect, RuIPr NPs being generally more active than RuItBu.
Position Paper: A Study of Web Search Engine Bias and its Assessment (2006)

Search engine bias has been seriously noticed in recent years. Several pioneering studies have reported that bias perceivably exists even with respect to the URLs in the search results. On the other hand, the potential bias with respect to the content of the search results has not been comprehensively studied. In this paper, we propose a two-dimensional approach to assess both the indexical bias and content bias existing in the search results. Statistical analyses have been further performed to present the significance of bias assessment. The results show that the content bias and indexical bias are both influential in the bias assessment, and they complement each other to provide a panoramic view with the two-dimensional representation.
Stimulating effects of quercetin on sperm quality and reproductive organs in adult male rats (2008)

Overall results indicate that quercetin might indirectly affect sperm quality through the stimulation of the sex organs, both at the cellular and organ levels, depending on the dose and the duration of treatment. Therefore, the use of quercetin as an alternative drug for treatment of male infertility should be considered.
The Functional <i>ccpA</i> Gene Is Required for Carbon Catabolite Repression in <i>Lactobacillus plantarum</i> (2001)

We report the characterization of the ccpA gene of Lactobacillus plantarum, coding for catabolite control protein A. The gene is linked to the pepQ gene, encoding a proline peptidase, in the order ccpA-pepQ, with the two genes transcribed in tandem from the same strand as distinct transcriptional units. Two ccpA transcription start sites corresponding to two functional promoters were found, expression from the upstream promoter being autogenously regulated through a catabolite-responsive element (cre) sequence overlapping the upstream +1 site. During growth on ribose, the upstream promoter showed maximal expression, while growth on glucose led to transcription from the downstream promoter. In a ccpA mutant strain, the gene was transcribed mainly from the upstream promoter in both repressing and non repressing conditions. Expression of two enzyme activities, beta-glucosidase and beta-galactosidase, was relieved from carbon catabolite repression in the ccpA mutant strain. In vivo footprinting analysis of the catabolite-controlled bglH gene regulatory region in the ccpA mutant strain showed loss of protection of the cre under repressing conditions.
Quasiparticle and phonon lifetimes in superconductors (1976)

Low-energy quasiparticle scattering, recombination, and branch-mixing lifetimes and phonon pair-breaking and scattering lifetimes are calculated for superconductors. The quasiparticle calculations relate these lifetimes to the low-frequency behavior of ${\ensuremath{\alpha}}^{2}(\ensuremath{\Omega})F(\ensuremath{\Omega})$. Results are obtained using the low-frequency approximate form ${\ensuremath{\alpha}}^{2}(\ensuremath{\Omega})F(\ensuremath{\Omega})=b{\ensuremath{\Omega}}^{2}$, with $b$ determined from electron tunneling measurements. For the strong-coupling superconductors Pb and Hg, the full tunneling form for ${\ensuremath{\alpha}}^{2}(\ensuremath{\Omega})F(\ensuremath{\Omega})$ is used. The phonon lifetimes are shown to depend on ${\ensuremath{\alpha}}^{2}(\ensuremath{\Omega})$. Results are compared with experiment.
A superconducting galvanometer employing Josephson tunnelling (1966)

Abstract The phenomenon of Josephson tunnelling has been applied to the detection of low voltages at liquid helium temperatures. A new technique for the manufacture of specimens displaying double-junction characteristics has been developed and a theory for their behaviour suggested. The junctions have been used in a practical voltmeter to achieve a sensitivity of 10−14 v with a time-constant of 1 sec; the sensitivity may be extended indefinitely for a proportionate increase in the time-constant.
High Energy-High Repetition Rate Fiber Laser System for Precision Micromachining with Fundamental and Second Harmonic Wavelengths (2006)

Interest in femtosecond laser micromachining has been growing for applications that require precise material removal or modification over very small features. Flat panel display manufacturing, lithography mask repair, semiconductor wafer scribing and optical waveguide writing are some examples where femtosecond pulse lasers are being studied. IMRA's latest experimental prototype FCPA is based on components similar to the production FCPA Jewel D-400. The latest design concept produces 10-J pulses at a repetition rate of up to 100 kHz or 1-J pulses at 1 MHz using Yb-doped fiber amplifier technology. Frequency-doubling produces 522-nm wavelength output with pulse energies up to 4 J. The higher pulse energy, relatively high repetition rate, availability of efficient frequency-doubling with a compact, reliable design will enable additional industrial applications. This paper describes the experimental results comparing the nonlinear optical loss through different types of transparent materials. The combination of the nonlinear absorption initiated by the ultrashort pulses and the heat accumulation from the high repetition rate enable some unique advantages over other lasers. The effect of the two different wavelengths (1045 nm and 522 nm) on processing of transparent materials is illustrated in several examples.
Multiplexing and transmission systems for all-optical networks (1990)

These systems are investigated as an application of new line coding schemes called paired block codes and multiblock codes, which use coding rule violations to simplify transmission frame structures so that limited functions of optical logic can be applied for processing. Redundancies are utilized for clock recovery through logical processing. The upper bound efficiency of this type of code and the jitter due to imperfect logical clock recovery are analyzed. An application of this type of line code to the multiplexing system for all-optical networks is investigated. Future superbroadband cross-connect systems are used as examples to compare wavelength division multiplexing, time division multiplexing and photonic TDM which is especially promising in super-high-speed applications (e.g. above 10 Gb/s). The application of a paired block code with a 3/1B4B format to such superbroadband multiplexing is studied. Multiplexing of STM 4 (600-Mb/s) signals into an all-optical frame format with 20- to 30-Gb/s capacity is investigated to demonstrate the efficacy of this type of multiplexing scheme.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Arcade Learning Environment: An Evaluation Platform for General Agents (2012)

In this article we introduce the Arcade Learning Environment (ALE): both a challenge problem and a platform and methodology for evaluating the development of general, domain-independent AI technology. ALE provides an interface to hundreds of Atari 2600 game environments, each one different, interesting, and designed to be a challenge for human players. ALE presents significant research challenges for reinforcement learning, model learning, model-based planning, imitation learning, transfer learning, and intrinsic motivation. Most importantly, it provides a rigorous testbed for evaluating and comparing approaches to these problems. We illustrate the promise of ALE by developing and benchmarking domain-independent agents designed using well-established AI techniques for both reinforcement learning and planning. In doing so, we also propose an evaluation methodology made possible by ALE, reporting empirical results on over 55 different games. All of the software, including the benchmark agents, is publicly available.
Oleoyl serine, an endogenous <i>N</i> -acyl amide, modulates bone remodeling and mass (2010)

Bone mass is determined by a continuous remodeling process, whereby the mineralized matrix is being removed by osteoclasts and subsequently replaced with newly formed bone tissue produced by osteoblasts. Here we report the presence of endogenous amides of long-chain fatty acids with amino acids or with ethanolamine (N-acyl amides) in mouse bone. Of these compounds, N-oleoyl-l-serine (OS) had the highest activity in an osteoblast proliferation assay. In these cells, OS triggers a Gi-protein-coupled receptor and Erk1/2. It also mitigates osteoclast number by promoting osteoclast apoptosis through the inhibition of Erk1/2 phosphorylation and receptor activator of nuclear-κB ligand (RANKL) expression in bone marrow stromal cells and osteoblasts. In intact mice, OS moderately increases bone volume density mainly by inhibiting bone resorption. However, in a mouse ovariectomy (OVX) model for osteoporosis, OS effectively rescues bone loss by increasing bone formation and markedly restraining bone resorption. The differential effect of exogenous OS in the OVX vs. intact animals is apparently a result of an OVX-induced decrease in skeletal OS levels. These data show that OS is a previously unexplored lipid regulator of bone remodeling. It represents a lead to antiosteoporotic drug discovery, advantageous to currently available therapies, which are essentially either proformative or antiresorptive.
Vision-Based Drivable Surface Detection in Autonomous Ground Vehicles (2006)

One of the primary tasks for most autonomous ground vehicles is road following. For safe maneuvering the vehicle needs to correctly identify the drivable surface. Our work is focused on the use of simple video cameras as the sensor devices. We describe a new machine learning approach to drivable surface detection that automatically combines a set of rectangular features and histogram backprojection based image segmentation algorithms to produce superior results. The machine learning algorithm is based on the AdaBoost method, one of a class of boosting techniques which are applicable to many image processing tasks such as object and face recognition or image segmentation. The algorithm is trained and tested on video data obtained from video cameras mounted on an autonomous tractor at our Queensland site. The algorithm approach, together with the simple feature-based weak classifiers used, produces significantly improved drivable surface detection results
Generalization of Voronoi Diagrams in the Plane (1981)

In this paper we study the Voronoi diagram for a set of N line segments and circles in the Euclidean plane. The diagram is a generalization of the Voronoi diagram for a set of points in the plane and has applications in wire layout, facility location, clustering and contouring problems. We present an $O(N(\log N)^2 )$ algorithm for constructing the diagram. It is an improvement of a previous known result which takes $O(Nc^{\sqrt {\log N} } )$ time. The algorithm described in this paper is also shown to be applicable under a more general metric if certain conditions are satisfied.
Proposals of Sphingobacterium faecium sp. nov., Sphingobacterium piscium sp. nov., Sphingobacterium heparinum comb. nov., sphingobacterium thalpophilum comb. nov. and two genospecies of the genus Sphingobacterium, and synonymy of Flavobacterium yabuuchiae and Sphingobacterium spiritivorum. (1992)

Seventeen strains of Cytophaga, Flavobacterium and Actinobacillus species were taxonomically characterized. DNA base composition of these strains ranged from 39.0 to 42.3mol%, and the menaquinone system was MK-7. All the strains contained sphingolipids with long-chain bases, which are characteristic of the genus Sphingobacterium. Based on their chemotaxonomic and physiological characteristics together with DNA/DNA hybridization studies, we propose two new species and two new combinations, Sphingobacterium faecium sp. nov., Sphingobacterium piscium sp. nov., Sphingobacterium heparinum comb. nov., Sphingobacterium thalpophilum comb. nov. and two genospecies of the genus Sphingobacterium. Flavobacterium yabuuchiae was found to be a synonym of Sphingobacterium spiritivorum.
Asthma Endotypes and an Overview of Targeted Therapy for Asthma (2017)

Guidelines for the management of severe asthma do not emphasize the measurement of the inflammatory component of airway disease to indicate appropriate treatments or to monitor response to treatment. Inflammation is a central component of asthma and contributes to symptoms, physiological, and structural abnormalities. It can be assessed by a number of endotyping strategies based on "omics" technology such as proteomics, transcriptomics, and metabolomics. It can also be assessed using simple cellular responses by quantitative cytometry in sputum. Bronchitis may be eosinophilic, neutrophilic, mixed-granulocytic, or paucigranulocytic (eosinophils and neutrophils not elevated). Eosinophilic bronchitis is usually a Type 2 (T2)-driven process and therefore a sputum eosinophilia of greater than 3% usually indicates a response to treatment with corticosteroids or novel therapies directed against T2 cytokines such as IL-4, IL-5, and IL-13. Neutrophilic bronchitis represents a non-T2-driven disease, which is generally a predictor of response to antibiotics and may be a predictor to therapies targeted at pathways that lead to neutrophil recruitment such as TNF, IL-1, IL-6, IL-8, IL-23, and IL-17. Paucigranulocytic disease may not warrant anti-inflammatory therapy. These patients, whose symptoms may be driven largely by airway hyper-responsiveness may benefit from smooth muscle-directed therapies such as bronchial thermoplasty or mast-cell directed therapies. This review will briefly summarize the current knowledge regarding "omics-based signatures" and cellular endotyping of severe asthma and give an overview of segmentation of asthma therapeutics guided by the endotype.
Prognostic Significance of Metastasis-Associated Protein S100A4 (Mts1) in Prostate Cancer Progression and Chemoprevention Regimens in an Autochthonous Mouse Model (2005)

S100A4 represents a promising marker for prostate cancer progression and could be employed as a biomarker in chemoprevention regimens.
Over-Expression of SlSHN1 Gene Improves Drought Tolerance by Increasing Cuticular Wax Accumulation in Tomato (2014)

Increasing cuticular wax accumulation in plants has been associated with improving drought tolerance in plants. In this study, a cDNA clone encoding the SlSHN1 transcription factor, the closest ortholog to WIN/SHN1 gene in Arabidopsis, was isolated from tomato plant. Expression analysis of SlSHN1 indicated that it is induced in response to drought conditions. The over-expression of SlSHN1 in tomato under the control of the constitutive CaMV 35S promoter produced plants that showed mild growth retardation phenotype with shiny and dark green leaves. Scanning electron microscopy showed that the over-expression of SlSHN1 in tomato resulted in higher cuticular wax deposition on leaf epidermial tissue when compared to non-transformed plants. Expression analysis in transgenic lines over-expressing SlSHN1 indicated that several wax-related synthesis genes were induced. Transgenic tomato plants over-expressing SlSHN1 showed higher drought tolerance when compared with wild type plants; this was reflected in delayed wilting of transgenic lines, improved water status and reduced water loss rate when compared with wild type plants. In conclusion, the SlSHN1 gene can modulate wax accumulation and could be utilized to enhance drought tolerance in tomato plant.
Shared knowledge, “glitches,” and product development performance (1999)

Much recent thought in strategy has stressed the importance of organizational integration for competitive advantage. Empirical studies of product development have supported this emphasis by correlating integrating practices and superior performance. We propose, from a resource-based or capability view, that this correlation results from integration leading to patterns of shared knowledge among firm members, with the shared knowledge constituting a resource underlying product development capability. To explore this connection, we examine the product development efforts of a scientific software company. We define the ‘glitch’ as a costly error possible only because knowledge was not shared, and measure the influence of glitches on firm performance. At this company, gaps in shared knowledge did cause the company to incur significant excess costs. We also identify a set of ‘syndromes’ that can lead to glitches, and measure the relative importance of these syndromes. The glitch concept may offer a general tool for practical measurement of the marginal benefits of shared knowledge. Copyright © 1999 John Wiley & Sons, Ltd.
Modulation of Turing Patterns in the CDIMA Reaction by Ultraviolet and Visible Light (2019)

We have carried out the first systematic study of the effects of ultraviolet light, both alone and in combination with visible white light, on Turing patterns in the chlorine dioxide-iodine-malonic acid (CDIMA) reaction. The ultraviolet light used has a sharp peak at 368 nm and can perturb the system selectively. It primarily decomposes chlorine dioxide in a zeroth-order reaction, and when it is used to illuminate Turing patterns, shrunken spots are formed with an imperfect hexagonal arrangement. The ultraviolet light competes directly with the visible white light via the photoreaction with dissolved chlorine dioxide, which prevents the total suppression of patterns at intermediate intensities of white light. These results suggest that specific wavelengths of light in the ultraviolet spectrum selectively modify the chemistry behind the pattern formation and can be utilized to generate novel self-organized structures under forcing conditions. We propose a modified Lengyel-Epstein model to incorporate the effect of ultraviolet illumination and obtain good qualitative agreement between simulations and experiments. These results support the idea that chlorine dioxide photoreaction is a key step in modulating CDIMA patterns under ultraviolet illumination.
Efficacy Comparison of Some New Natural-Product Herbicides for Weed Control at Two Growth Stages (2009)

There is an urgent need to accelerate the development and implementation of effective organic-compliant herbicides that are environmentally safe and that help the producer meet increasing consumer demand for organic products. Therefore, greenhouse experiments were conducted to evaluate the effectiveness of acetic acid (5%), acetic acid (30%), citric acid (10%), citric acid (5%) + garlic (0.2%), citric acid (10%) + garlic (0.2%), clove oil (45.6%), and corn gluten meal (CGM) compounds as natural-product herbicides for weed control. The herbicides were applied to the broadleaf weeds stranglervine, wild mustard, black nightshade, sicklepod, velvetleaf, and redroot pigweed and to narrowleaf weeds crowfootgrass, Johnsongrass, annual ryegrass, goosegrass, green foxtail, and yellow nutsedge. The herbicides were applied POST at two weed growth stages, namely, two to four and four to six true-leaf stages. CGM was applied PPI in two soil types. Citric acid (5%) + garlic (0.2%) had the greatest control (98%) of younger broadleaf weeds, followed by acetic acid (30%) > CGM > citric acid (10%) > acetic acid (5%) > citric acid (10%) + garlic (0.2%), and clove oil. Wild mustard was most sensitive to these herbicides, whereas redroot pigweed was the least sensitive. Herbicides did not control narrowleaf weeds except for acetic acid (30%) when applied early POST (EPOST) and CGM. Acetic acid (30%) was phytotoxic to all broadleaf weeds and most narrowleaf weeds when applied EPOST. Delayed application until the four- to six-leaf stage significantly reduced efficacy; acetic acid was less sensitive to growth stage than other herbicides. These results will help to determine effective natural herbicides for controlling weeds in organic farming.
Room Temperature Generation of Terahertz Radiation from Dual Grating Gate HEMT's (2008)

International audience
Analysis of Sweet cherry (Prunus avium L.) Leaves for Plant Signal Molecules That Activate the syrB Gene Required for Synthesis of the Phytotoxin, Syringomycin, by Pseudomonas syringae pv syringae (1995)

An important aspect of the interaction of Pseudomonas syringae pv syringae with plant hosts is the perception of plant signal molecules that regulate expression of genes, such as syrB, required for synthesis of the phytotoxin, syringomycin. In this study, the leaves of sweet cherry (Prunus avium L.) were analyzed to determine the nature of the syrB-inducing activity associated with tissues of a susceptible host. Crude leaf extracts yielded high amounts of total signal activity of more than 12,000 units g-1 (fresh weight) based on activation of a syrB-lacZ fusion in strain B3AR132. The signal activity was fractionated by C18 reversed-phase high-performance liquid chromatography and found to be composed of phenolic glycosides, which were resolved in three regions of the high-performance liquid chromatography profile, and sugars, which eluted with the void volume. Two flavonol glycosides, quercetin 3-rutinosyl-4[prime]-glucoside and kaempferol 3-rutinosyl-4[prime]-glucoside, and a flavanone glucoside, dihydrowogonin 7-glucoside, were identified. The flavonoid glycosides displayed similar specific signal activities and were comparable in signal activity to arbutin, a phenyl [beta]-glucoside, giving rise to between 120 and 160 units of [beta]-galactosidase activity at 10 [mu]M. Although D-fructose exhibits intrinsic low level syrB-inducing signal activity, D-fructose enhanced by about 10-fold the signal activities of the flavonoid glycosides at low concentrations (e.g. 10 [mu]M). This demonstrates that flavonoid glycosides, which represent a new class of phenolic plant signals sensed by P. s. syringae, are in sufficient quantities in the leaves of P. avium to activate phytotoxin synthesis.