gebhart/patrepeval huggingface dataset:
Darstellung und Kristallstruktur von Silber-Barium-Thiogermanat(IV). Ag<sub>2</sub>BaGeS<sub>4</sub> / Preparation and Crystal Structure of Silver-Barium-Thiogermanate(IV). Ag<sub>2</sub>BaGeS<sub>4</sub> (1979)

Abstract Ag 2 BaGeS 4 was prepared for the first time and the crystal structure determined using X-ray methods, a - b = 682,g; c = 801, 7 pm, Space group I4̅2 m (No. 121) tetragonal. The atomic parameters and interatomic distances are reported and the structure is discussed.
Software-defined control of the virtualized mobile packet core (2015)

Mobile packet core networks are undergoing major changes to meet the requirements of the future data tsunami, enhance network flexibility, and reduce both CAPEX and OPEX. In this regard, SDN and NFV technologies have gained great momentum among the teleos, with the promise of interoperability, programmability, and on-demand dynamic provisioning. In this article, we present work being developed in the Mobile Packet Core project within the ONF Wireless & Mobile Working Group regarding SDN architecture for the Mobile Packet Core. In addition, we propose an SDN-based MPC in the NFV context in order to facilitate dynamic provisioning of MPC network functions. Finally, a potential control architecture considering both SDN and NFV is proposed.
The effect of 2% niacinamide on facial sebum production (2006)

Topical 2% niacinamide may be effective in lowering the SER in Japanese individuals and CSL in Caucasian individuals.
지속성 외래 복막투석 환자에서 아포지단백 E 다형성이 죽상경화성 심혈관계 질환 발병에 미치는 영향 (1998)

Specific apolipoprotein(apo) E genotype has been suggested as a risk factor for atherosclerosis in the general population. Lipid metabolism is known to be modulated by apo E genotype. In this study, we measured apo E genotype, lipoprotein(a)[Lp(a)], apo A phenotype and other lipoproteins in 50 CAPD patients, and evaluated the association of lipid parameters with atherosclerotic cardiovascular disease. Dipyridamole thallium scan with SPECT and ankle- arm blood pressure index(AABI) were performed in all the subjects. The patients who had positive finding in at least one of the two test were considered to have atherosclerotic cardiovascular disease [CVD(＋)]. Fifteen patients had evidence of cardiovascular disease. Serum Lp(a) concentration(median; interquartile range) of CVD(＋) patients(n=15, 62.0 mg/dl; 29.5－82.3) was not different from that of CVD(－) patients(n=35, 65.1mg/dl; 34.3－89.9). The frequency distribution of apo(a) phenotype of CVD (＋) patients did not differ from that of CVD(－) patients. In addition, there were no differences of other lipoproteins levels and lipid profiles between two group. However, significant difference in the frequency distribution of apo E genotype(E2; 6.7 vs 20%, E3; 40 vs 68.6%, E4; 53.3 vs 
between CVD(＋) and CVD(－) patients. After stratifying the subjects according to the apo E genotype, we observed no difference of lipid profiles, apolipoproteins and Lp(a) concentration in E2, E3, E4. Multivariate regression analysis of risk factors for CVD revealed age and the presence of apo E4 phenotype as independent risk factors of atherosclerotic cardiovascular disease. In conclusion, Apo E4 genotype could be an independent risk factor of atherosclerotic cardiovascular disease in CAPD patients.
System Modeling in Cellular Biology: From Concepts to Nuts and Bolts (2007)

Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling in biology makes the relevant background material from all pertinent fields accessible to researchers with different backgrounds.The emerging area of systems level modeling in cellular biology has lacked a critical and thorough overview. This book fills that gap. It is the first to provide the necessary critical comparison of concepts and approaches, with an emphasis on their possible applications. It presents key concepts and their theoretical background, including the concepts of robustness and modularity and their exploitation to study biological systems; the best-known modeling approaches, and their advantages and disadvantages; lessons from the application of mathematical models to the study of cellular biology; and available modeling tools and datasets, along with their computational limitations.
A new devised skirted elephant trunk technique. (1999)

A simple and effective new elephant trunk technique was devised and applied to two patients with a successful result. In advance before the operation, an arch graft with a skirted elephant trunk was made. This was done by inserting a smaller, 22 mm diameter sized graft into the arch graft at the distal end and suturing it so as to leave a skirt extending over the smaller graft. This configuration facilitates the distal anastomosis and effectively shortens anastomotic time.
The tangram framework (embedded tutorial) (2001)

Asynchronous CMOS circuits have the potential for very low power consumption, because they only dissipate when and where active. In addition they have favorable EMC properties, since they emit less energy, which in addition is evenly distributed over the spectrum. The Tangram framework supports the design of asynchronous circuits in a high-level programming language. Using this framework we have designed several chips, such as for instance for pagers and smart cards, which are clearly superior to synchronous designs.
Efficacy of Selected Insecticides Against Thrips on Cotton, 1997 (1998)

Abstract Cotton was planted on 5 May at the Macon Ridge location of the Northeast Research Station in a Gigger Gilbert silt loam. Plots consisted of 2 rows (40 inch centers) X 50 ft. Treatments were arranged in a RCB with 4 replications. Insecticides were applied on 30 May with a tractor-mounted boom calibrated to deliver 10 gpa at 21 psi with 80015 flat-fan noz-zles (2/row). Treatments were evaluated by randomly collecting 10 plants from each plot. Plots were sampled on 2 Jun (3 DAT), 4 Jun (5 DAT), and 6 Jun (7 DAT). Plot samples were processed with a whole plant-washing procedure. Thrips (adult and immature) were counted using a dissecting microscope.Plots received 2.49 inches of rainfall on 30 May and 0.73 inches of rainfall on 4 Jun. Data were analyzed with ANOVA, and means were separated ac-cording to DMRT.
THE YAMAHA NS10M: TWENTY YEARS A REFERENCE MONITOR. WHY? (2024)

Historically, one of the most hotly contested topics of discussion in the recording industry has been that of studio monitoring. The 75 years since the invention of the moving coil loudspeaker have not culminated in anything approaching a consensus of a universal monitor. It would appear that a general trend has been to use large, full-range monitors, with frequent reference to the smaller mixing monitors, during the recording process, and vice versa during mixing. The loudspeakers often chosen for mixing are those which lead the mixing personnel to produce, in the mixing environment, masters which travel well to their use by the record buyers. The mixing environment is rarely representative, however, of the final use environments. This situation is often dictated by the need to have a mixing console and effects rack in the middle of the room, together with sound isolation requirements which can take recording studios a further step away from domestic acoustics.
Multi-tone transmission for asymmetric digital subscriber lines (ADSL) (2002)

Multi-tone transmission is a potentially viable technique for application on asymmetric digital subscriber lines (ADSLs). The results of a preliminary study on the performance of an ideal discrete multi-tone (DMT) signaling technique for a 1.6-Mb/s ASDL are presented. The performance margins using single-tone 16-point quadrature amplitude modulation (QAM) with ideal decision feedback equalization (DFE) are presented. The feedforward filter of the DFE is a quarter-baud spaced fractionally spaced equalizer (FSE). The interference is assumed to be the sum of far-end crosstalk (FEXT) and additive white Gaussian noise (AWGN). The subscriber loops are assumed to be in a plant environment where the maximum resistance does not exceed 1300 /spl Omega/. The projected performance of an ideal DMT with a sampling rate of 1.024 MHz and 256-subchannel segmentation offers potential margin enhancement up to 3 dB over a quarter baud-spaced FSE-based 16-QAM signaling.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Generalized Correlation Coefficient for the General Two-Treatment Crossover Design (2010)

This article extends the correlation methodology developed by Chinchilli et al. (2005 Chinchilli , V. M. , Phillips , B. R. , Mauger , D. T. , Szefler , S. J. ( 2005 ). A general class of correlation coefficients for the 2 × 2 crossover design . Biometr. J. 47 : 1 – 10 .[Crossref] , [Google Scholar]) for the 2 × 2 crossover design to more complex crossover designs for clinical trials. We describe how the methodology can be adapted to a general type of two-treatment crossover design which includes either at least two sequences or at least two treatment periods or both. We then derive the asymptotic theory for the corresponding correlation statistics, investigate the statistical accuracy of the estimators via bootstrap analyses, and demonstrate their use with two real data examples.
IT ENABLED SUPPLY CHAIN MANAGEMENT (2007)

The paper highlights the importance of Information Technology (IT) in Supply Chain Management. The main objectives of the paper are to study the various tools of IT, which helps to make optimum decision at every stage of a supply chain. The whole Supply Chain has been divided into five modules, namely, source, make, store, distribute, and market. The research is exploratory in nature exploring each module and how IT tools helps in making each module efficient and effective and finally integrating them to get the best possible result. The paper is concluded by presenting a case study of Diesel Locomotive Works, Varanasi, a premier institution manufacturing diesel locomotives for both national ad international customers. The case study shows how IT has helped DLW to manage its Supply Chain in reducing its costs, having better relationship with both its suppliers/vendors and customers, and give better product and services to its customers.
Finding folds: on the appearance and identification of occlusion (2005)

A natural sequel to edge detection is the interpretation of edges. This interpretation can provide useful information to various computer vision processes, including recognition, reconstruction, and tracking. In this paper we consider the problem of identifying occlusion edges in a single image. We examine the appearance of occlusion edges under variable illumination, both analytically and empirically, and find that the pattern of shading in the neighborhood of occlusion edges is a stable feature. Finally, we derive a filter for detecting occlusion and present the results of its application.
Video coding using global motion temporal filtering (2009)

Recent deblocking techniques are based on spatial filtering. We present a new deblocking technique based on temporal filtering of spatially aligned frames. This approach is used in an H.264/AVC coding environment. The algorithm estimates the ideal amount of frames used for temporal filtering at the encoder side. In that way it is assured that the receiver is presented with the best possible visual quality in terms of structural similarity. Theoretical consideration of the problem proves the concept of the new approach. Experimental evaluation shows that the new temporal deblocking filter significantly improves visual quality and reduces bit rate compared to common H.264/AVC deblocking by up to 18%.
High-temperature tolerant diamond diode for carbon monoxide gas detection (1998)

A high-temperature tolerant microelectronic carbon monoxide gas sensor has been developed. This device is based on a diamond diode in the form of catalytic-metal/adsorptive-oxide/intrinsic-diamond/semiconductor-diamond structure. The gas sensing performance and detection mechanisms have been studied over a wide temperature range (50–500 °C). The gas sensitivity of the sensor is large, fast, repeatable, and reproducible. Gas detection mechanism is attributed to the modification of the oxygen vacancies in the SnOx layer of the sensor. This diamond diode sensor can be utilized in applications that require a sensor to operate at a wider operating temperature range.
Facile dissociation of molecular nitrogen using lanthanide surfaces: Towards ambient temperature ammonia synthesis (2020)

A combined experimental and computational study is reported on a hitherto unrecognised single lanthanide catalyst for the breaking of molecular nitrogen and formation of ammonia at ambient temperature and low pressure. We combine in situ electrical conductance and electron diffraction measurements to track the conversion from the lanthanide metals to the insulating lanthanide nitrides. The efficiency of the conversion is then interpreted using $\mathrm{DFT}+U$ calculations, suggesting a molecular nitrogen dissociation pathway separate from that well established for transition metals. Finally, we show that exposure of the lanthanide surfaces to both molecular nitrogen and hydrogen results in the formation of ammonia.
Modulation of CYP1A2 enzyme activity by indoleamines (1998)

Recent evidence supports a role for the CYP2D6 enzyme in the metabolism of tryptamine. Because of the partial overlapping between substrate and inhibitor specificities that characterize some cytochrome P450 enzymes, these finding raise the possibility that other cytochrome P450 enzymes may be modulated by endogenous compounds. In the present study, the occurrence of modulatory effect of 17 neurotransmitters, precursors and metabolites on the cytochrome P450 1A2 (CYP1A2) enzyme activity was studied in human liver microsomes. Two indoleamines, serotonin and tryptamine, showed a competitive inhibitory effect on the high-affinity component of the phenacetin O-de-ethylase activity. Both substances induced an inhibition of 100% of the activity, with Ki values of 35 and 45 microns for serotonin and tryptamine, respectively. The inhibitors did not affect the microsomal NADPH-reductase activity. Other substances, which were either poor or partial inhibitors, were dopamine, L-tyrosine, tryptophol, 5-hydroxytryptophol, adrenaline, indole-3-acetaldehyde, 5-hydroxytryptophan, noradrenaline, vanillylmandelic acid, indole-3-acetic acid, dihydroxyphenylacetic acid, and homovanillic acid. L-tryptophan, dihydroxyphenylalanine and 5-hyroxyindole acetic acid induced very low or no inhibitory effect. Tryptamine and serotonin metabolism in human liver microsomes was studied after inhibition of monoamine oxidase activity with the unspecific MAO inhibitor pargyline. Both serotonin and tryptamine were metabolized in human liver microsomes. However, the metabolism of both indoleamines was not significantly inhibited with the CYP1A2-specific inhibitor furafylline, thus indicating that the inhibition of CYP1A2 was not related to metabolic activity of the CYP1A2 enzyme on serotonin or tryptamine. The CYP1A2 enzyme is expressed in brain and is involved in the metabolism of psychoactive drugs. Therefore, the fact that endogenous compounds could modulate the CYP1A2 activity suggests that local activity of brain CYP1A2 might be susceptible to local regulatory mechanisms. This may have important clinical implications, one of them being that CYP1A2 activity in brain tissue might correlate poorly with that of liver, as observed in vivo. In addition, the influence of indoleamines on CYP1A2 activity might be partly responsible for a number of associations of CYP1A2 activity with nutritional and environmental factors.
[New possibilities in oral immunoprophylaxis of newborn diarrhea in calves--a field study using specific egg antibodies]. (1993)

To investigate the effect of oral immunoprophylaxis in diarrhea of newborn calves egg powder with antibodies specific to E. coli K99 (ETEC) and rotavirus were used in a field trial in south west Germany. Fourteen farms with a total of 105 calves were selected. Egg powder (21 g per day) was fed as a supplement to the regular diet for the first 14 days after birth. Animals of the control group received egg powder derived from hens not immunized with the antigens. Frequency, duration and severity of diarrhea, fecal dry matter and weight gain were examined in order to evaluate the influence of the specific egg powder. Using a Lactovac test kit pathogens were detected in the feces of 76.2% of the calves, with 24.7% infected with E. coli K99, 39.1% with rotavirus, 19.0% with coronavirus and 32.4% with cryptosporidia. An overall reduction in diarrhea frequency from 68.5% to 52.9% was observed in calves fed with specific antibodies. Animals with an E. coli K99 infection showed a reduction from 92.3% to 30.7% and those infected exclusively with E. coli K99 from 83.3% to 0%. The duration of diarrhea was significantly reduced (42 h) in animals fed with specific antibodies in comparison to the control animals (60 h). With the exception of animals infected with coronavirus a marked reduction in the severity of diarrhea was observed in antibody treated calves. During the first 14 days after birth antibody treated calves showed a weight gain of 5.6 kg on average in comparison with 3.5 kg in the control group.(ABSTRACT TRUNCATED AT 250 WORDS)
The association of ERCC1 and clinical outcomes of women with advanced ovarian cancer (2008)

5575 Background: To determine the significance of excision repair cross complementation group 1 (ERCC1) in optimally debulked stage IIIC serous ovarian cancer after platinum and taxol chemotherapy. Methods: All patients were identified from two academic health centers. Pretreatment tumor biopsy specimens were analyzed for ERCC1 expression by immunohistochemistry. Patients were divided into two groups: those who recurred or had persistent disease within 12 months, and those who recurred after 12 months. Pathologic evaluation was performed without identifying clinical information. Time to progression and survival analyses were estimated using Kaplan Meier method. Results: Of 96 patients, the median age was 59 years. 68% were White, 18% Asian and 13% Other. All patients underwent primary surgical staging and were diagnosed with FIGO stage IIIC disease. All tumors were of papillary serous histology. The grading of immunostaining revealed that 16% of tumors had grade 1, 60% grade 2, and 24% had grade 3 staining intensity. In the subset of patients with 3+ staining intensity, the median time to progression was 12 months compared to 19 months in those who had grade 1 or 2 immunostaining (p=0.099). There were no statistical differences in the overall survival between these two groups of patients. Multivariate analysis was performed to identify independent prognostic factors for disease-free and overall survival. Conclusions: Our data suggest that ERCC1 expression may predict for early recurrence in this pilot study. Further studies are warranted to confirm these findings. No significant financial relationships to disclose.
Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy (2014)

In response to stress, the heart undergoes extensive cardiac remodeling that results in cardiac fibrosis and pathological growth of cardiomyocytes (hypertrophy), which contribute to heart failure. Alterations in microRNA (miRNA) levels are associated with dysfunctional gene expression profiles associated with many cardiovascular disease conditions; however, miRNAs have emerged recently as paracrine signaling mediators. Thus, we investigated a potential paracrine miRNA crosstalk between cardiac fibroblasts and cardiomyocytes and found that cardiac fibroblasts secrete miRNA-enriched exosomes. Surprisingly, evaluation of the miRNA content of cardiac fibroblast-derived exosomes revealed a relatively high abundance of many miRNA passenger strands ("star" miRNAs), which normally undergo intracellular degradation. Using confocal imaging and coculture assays, we identified fibroblast exosomal-derived miR-21_3p (miR-21*) as a potent paracrine-acting RNA molecule that induces cardiomyocyte hypertrophy. Proteome profiling identified sorbin and SH3 domain-containing protein 2 (SORBS2) and PDZ and LIM domain 5 (PDLIM5) as miR-21* targets, and silencing SORBS2 or PDLIM5 in cardiomyocytes induced hypertrophy. Pharmacological inhibition of miR-21* in a mouse model of Ang II-induced cardiac hypertrophy attenuated pathology. These findings demonstrate that cardiac fibroblasts secrete star miRNA-enriched exosomes and identify fibroblast-derived miR-21* as a paracrine signaling mediator of cardiomyocyte hypertrophy that has potential as a therapeutic target.
Texture analysis for survival prediction of pancreatic ductal adenocarcinoma patients with neoadjuvant chemotherapy (2016)

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death in the United States. The five-year survival rate for all stages is approximately 6%, and approximately 2% when presenting with distant disease.<sup>1</sup> Only 10-20% of all patients present with resectable disease, but recurrence rates are high with only 5 to 15% remaining free of disease at 5 years. At this time, we are unable to distinguish between resectable PDAC patients with occult metastatic disease from those with potentially curable disease. Early classification of these tumor types may eventually lead to changes in initial management including the use of neoadjuvant chemotherapy or radiation, or in the choice of postoperative adjuvant treatments. Texture analysis is an emerging methodology in oncologic imaging for quantitatively assessing tumor heterogeneity that could potentially aid in the stratification of these patients. The present study derives several texture-based features from CT images of PDAC patients, acquired prior to neoadjuvant chemotherapy, and analyzes their performance, individually as well as in combination, as prognostic markers. A fuzzy minimum redundancy maximum relevance method with leave-one-image-out technique is included to select discriminating features from the set of extracted features. With a naive Bayes classifier, the proposed method predicts the 5-year overall survival of PDAC patients prior to neoadjuvant therapy and achieves the best results in terms of the area under the receiver operating characteristic curve of 0:858 and accuracy of 83:0% with four-fold cross-validation techniques.