gebhart/patrepeval huggingface dataset:
The Blood Group Antigen Ul^a (Karhula) (1968)

The serum of a Finnish patient contains an antibody to a previously unknown red cell antigen provisionally called Ul^a. The antigen is possessed by 2.6% of 2620 Helsinki blood donors though in certain Finnish isolates it is more frequent: it is inherited as a dominant character. The symbol Ula is provisional because, although the antigen was shown by independent segregation in families not to belong to the ABO, MN Ss, P, Rh, Lutheran, secretor, Duffy, Kidd or Dornbrock systems, nor to be X- or Y-linked, it has yet to be shown to be genetically independent of the versatile Kell system and of the Yt and Diego systems.
Enhanced distribution channel access &#x2014; Modification of the intial &amp; thereafter CW (EDCA-MITCW) (2012)

In recent years, IEEE 802.11 Wireless Local Area Networks (WLANs) have emerged as one of the prevailing technologies for the broadband wireless access. Although IEEE802.16 wireless network has become a newer generation of wireless network, it will be used as wireless metropolitan area network in the beginning because of its price. IEEE 802.11 network will continue to be the most important wireless local area network (WLAN) because of inexpensive price and easy installation. There are increasing number of applications found for WLAN which include real time traffic like Voice over IP and others. This causes more and more intensive research efforts on the quality of service (QoS) issues in “carrier sense multiple access/ collision avoidance (CSMA/CA)” for WLAN. Until now, the standard of IEEE 802.11e has stated some scenarios for this problem. In this paper, we focus on the adjustment of contention window of CSMA/CA after successful transmission of frame and the collision of multiple frames. In IEEE 802.11e, different contention window is given to different class of traffic. This will give higher priority to real traffic in a contention protocol. However, several researches have shown this method does not work very well in high load situation. For this, we propose a method to adjust the minimum contention window (CW <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">min</sub> ) for different class of traffic according the number of stations and the collision rate of this class. Also, we propose a method to find the new contention window after collision. Simulation shows our protocol will have a good result under both light and heavy load situations.
Charge Clamps of Lysines and Hydrogen Bonds Play Key Roles in the Mechanism to Fix Helix 12 in the Agonist and Antagonist Positions of Estrogen Receptor α: Intramolecular Interactions Studied by the <i>Ab Initio</i> Fragment Molecular Orbital Method (2014)

The mechanism to fix helix 12 (H12) in the agonist/antagonist position, which is involved in controlling transcriptional activation, of the human estrogen receptor α ligand binding domain (hERαLBD) is studied by using fragment molecular orbital calculations at the Møller-Plesset second-order perturbation levels to analyze inter-fragment interaction energies (IFIEs), electrostatic potentials (ESPs), and atomic charges. The mutually attractive and complementary relationships between H12 and highly conserved Lys529/Lys362 are shown through the IFIEs and ESPs. The highly conserved Lys529 and Lys362 are found to have strong attractive interactions with the anionic residues of H12 in the agonist and antagonist positions, respectively, thus playing roles of charge clamps to fix H12. Additionally, intramolecular interactions between the neutral residues of H12 including the LXXML motif and the other part of hERα are strengthened by the hydrogen bonds and polarization. It is noted that the highly conserved Asp351 forms a hydrogen bond with Leu540 of H12 in the hERα-agonist complex, while it is also involved in stabilization of ligand binding in the hERα-antagonist complex. The charges of residues at the interface between H12 and the other part of hERα approach approximately neutral upon forming the agonist/antagonist binding conformation so as to relax the electrostatic repulsion caused by the negative charges of H12 and the other part of hERα. Our observations would thus provide useful information to control the H12 position for regulation of transcription in hERα and other nuclear receptors.
Eosinophil Involvement in Atopic Dermatitis as Reflected by Elevated Serum Levels of Eosinophil Cationic Protein (1992)

Eosinophil cationic protein (ECP), one of the eosinophil granule proteins, is released during allergic reactions. We investigated the possibility of correlations among the serum levels of ECP, clinical activity, and eosinophil number in patients with atopic dermatitis (AD). Forty-four patients with AD and 25 normal, non-atopic subjects were studied. ECP was quantitated by a double antibody radioimmunoassay. The levels of serum ECP correlate with the grading of severity of clinical evaluations in AD. The patients with severe and moderate AD had significantly higher ECP concentrations than normal controls (p less than 0.001); mild AD had levels identical with those of control groups. A positive correlation was observed between the number of peripheral blood eosinophils and serum ECP levels in the severe cases (r = 0.67, p less than 0.05). Furthermore, these ECP levels significantly decreased in response to either improvement of clinical severity of AD or decreased numbers of blood hypodense eosinophils in anti-allergic drug-treated patients. No coefficient of correlation was observed between serum ECP and IgE levels. These findings indicate that eosinophils may release their granular contents, including ECP, into the peripheral circulation and/or inflammatory skin lesions and subsequently provoke a clinical exacerbation by stimulating allergic reactions.
Image precision silhouette edges (1999)

Article Image precision silhouette edges Share on Authors: Ramesh Raskar University of North Carolina at Chapel Hill University of North Carolina at Chapel HillView Profile , Michael Cohen Microsoft Research Microsoft ResearchView Profile Authors Info & Claims I3D '99: Proceedings of the 1999 symposium on Interactive 3D graphicsApril 1999 Pages 135–140https://doi.org/10.1145/300523.300539Online:26 April 1999Publication History 107citation1,038DownloadsMetricsTotal Citations107Total Downloads1,038Last 12 Months30Last 6 weeks9 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Complexity of MRI induced heating on metallic leads: Experimental measurements of 374 configurations (2008)

Our findings highlight the factors that have significant effects on MRI induced heating of implanted wires and leads. These factors must be taken into account by those who plan to study or model MRI heating of implants. Also our data should help those who wish to develop guidelines for defining safe medical implants for MRI patients. In addition, our database of the entire set of measurements can help those who wish to validate their numerical models of implants that may be exposed to MRI systems.
Micro Swimming Robots Based on Small Aquatic Creatures (2010)

The swimming behavior of small aquatic creatures was analyzed using the high speed video camera system. Based on the swimming analysis of the aquatic creatures, the micro swimming mechanism and micro diving robot propelled by alternating magnetic field were produced. The swimming characteristics of the micro mechanism and micro diving robot were developed. The swimming mechanism and diving robot swam successfully in the water. Frequency characteristics of the swimming mechanism and diving beetle robot were examined. The diving robot showed the higher swimming velocities at f0=4-12Hz. These experiments show the possibility of achievement of the micro robot driving by the wireless energy supply system. The results obtained are summarized as follows; (1) In the power stroke of the diving beetle swimming, hind legs are extended and driven backward to generate forward thrust. While in recovery stroke, hind legs are returned slowly to their initial position. (2) In forward swimming of the dragonfly nymph, only the fore pair and the middle pair of legs are active as a thrust generator. The orbits of fore- and middle-legs show almost the same, and draw the circle partially of the orbit. (3) The micro swimming mechanism composed of the NdFeB permanent magnet and film fin are driven by the alternating magnetic field. The swimming velocity of the micro mechanism depends on the frequency of alternating magnetic field at the constant voltage. (4) Flow visualization around the micro mechanism was created by the motion of powder and slow shutter speed photographic technique. The forward and backward surface flows and vortex flows around the micro mechanism were generated by the robot driving. (5) Visualization photographs of flow field around the tethered opossum shrimp show the generation of tow votices in right and left sides of the body. (6) The diving robot can dive into the water by sweeping the frequency of magnetic field. The diving robot can swim backward by the change of magnetic field frequency.
How children eat may contribute to rising levels of obesity Children's eating behaviours: An intergenerational study of family influences (2009)

Abstract The term ‘obesogenic environment’ is rapidly becoming part of common phraseology. However, the influence of the family and the home environment on children's eating behaviours is little understood. Research that explores the impact of this micro environment and intergenerational influences affecting children's eating behaviours is long overdue. A qualitative, grounded theory approach, incorporating focus groups and semi-structured interviews, was used to investigate the family environment and specifically, the food culture of different generations within families. What emerged was a substantive theory based on ‘ordering of eating’ that explains differences in eating behaviours within and between families. Whereas at one time family eating was highly ordered and structured, typified by the grandparent generation, nowadays family eating behaviours are more haphazard and less ordered, evidenced by the way the current generation of children eat. Most importantly, in families with an obese child eating is less ordered compared with those families with a normal weight child. Ordering of eating' is a unique concept to emerge. It shows that an understanding of the eating process is crucial to the development and improvement of interventions targeted at addressing childhood obesity within the family context.
Tip-enhanced near-field CARS microscopy for molecular nano-imaging (2005)

Optical microscopy that can visualize the molecular vibration with a nanometric spatial resolution has been realized by a combination of near-field optics and coherent anti-Stokes Raman scattering (CARS) spectroscopy. A metallic probe with a sharp tip is used to strongly enhance optical near-field in the local vicinity of the tip owing to the excitation of local surface plasmon polariton. CARS signals of molecules in the local area can be strongly induced by the plasmonic field. We have visualized DNA molecules and single-walled carbon nanotubes (SWNTs) with a spatial resolution far beyond the diffraction limit by the tip-enhanced near-field CARS microscopy.
완벽주의와 우울에 관한 성경적 상담 (2007)

대학생의 시기는 자아개념과 자아 정체성 발달, 성역할의 발달, 영적 및 도덕적 발달이라는 발달 과업을 이루어야 하는 중요한 시기이며, 자신의 선택과 책임의 영역이 넓어진 대학생활에도 적응해야 한다. 더구나 사회 진출을 준비하는 시기로서 사회가 요구하는 인재가 되어야 한다는 압박감과 취업에 대한 불안감 등은 대학생들에게 완벽주의를 강화시킬 수 있다. 이러한 완벽주의가 기능적으로 작용할 때는 보람감, 성취감 등을 느끼게 되지만, 역기능적으로 작용할 때는 수행에 대한 높은 기대, 불안, 분노, 대인관계의 어려움, 우울 등의 인지적 · 정서적 · 신체적으로 부적응이 나타나고 심각한 성격장애로 발전할 수도 있다. 본 연구에서는 완벽주의의 역기능적인 면을 중심으로 대학생의 완벽주의와 우울에 대해 연구하였고, 완벽주의와 우울의 상관성을 알아보기 위해 기독대학생들을 대상으로 설문을 한 후 결과를 분석했다. 설문 분석 결과 완벽주의는 부모양육태도와 상관성이 높고, 우울과도 상관성이 있는 것으로 나타났다. 그리고 신앙성숙도가 높을수록 우울은 낮게 나타났다. 마지막으로 위의 결과들에 대해 성경적 상담학적으로 어떻게 접근할 것인지 연구해보았다. 먼저 C.C.E.F의 성경적 상담의 개념, 원리와 방법을 살펴보고, 대학생의 완벽주의와 우울을 성경적 관점에서 조명해보았다. 또 인간은 하나님께 범죄하여 타락하였고, 인간의 문제(열매)는 마음의 문제(막7장)라는 성경적 입장에서 완벽주의와 우울에 대한 마음의 문제를 알아보고, 성경적 상담으로 어떻게 상담할 것인지 연구해 보았다. 그리고 완벽주의로 인해 우울을 겪고 있는 피상담자에 대해 성경적 상담의 방법을 적용하여 상담한 결과, 하나님의 역사하심과 성경적 대안을 통해 회복되는 과정을 보게 되었다.
Machine learning in multiexposure laser speckle contrast imaging can replace conventional laser Doppler flowmetry (2019)

Laser speckle contrast imaging (LSCI) enables video rate imaging of blood flow. However, its relation to tissue blood perfusion is nonlinear and depends strongly on exposure time. By contrast, the perfusion estimate from the slower laser Doppler flowmetry (LDF) technique has a relationship to blood perfusion that is better understood. Multiexposure LSCI (MELSCI) enables a perfusion estimate closer to the actual perfusion than that using a single exposure time. We present and evaluate a method that utilizes contrasts from seven exposure times between 1 and 64 ms to calculate a perfusion estimate that resembles the perfusion estimate from LDF. The method is based on artificial neural networks (ANN) for fast and accurate processing of MELSCI contrasts to perfusion. The networks are trained using modeling of Doppler histograms and speckle contrasts from tissue models. The importance of accounting for noise is demonstrated. Results show that by using ANN, MELSCI data can be processed to LDF perfusion with high accuracy, with a correlation coefficient R = 1.000 for noise-free data, R = 0.993 when a moderate degree of noise is present, and R = 0.995 for in vivo data from an occlusion-release experiment.
Transforming multidimensional models into OWL-DL ontologies (2012)

Business intelligence is based on data warehouses. Data warehouses use a multidimensional model, which represents relevant facts and their measures according to different dimensions. Based on this model, OLAP cubes may be defined, enabling decision makers to analyze and synthesize data. Ontologies (and, more specifically, OWL ontologies) are a key component of the semantic Web. This paper proposes an approach to represent multidimensional models as OWL-DL ontologies. To this end, it presents the multidimensional metamodel, the concepts of OWL-DL, and transformation rules for mapping a multidimensional model into and OWL-DL ontology. It then illustrates application to a case study with a simplified example of a spatiotemporal data warehouse. The transformation rules are refined to deal with spatiotemporal data warehouses, applied step by step, and the resulting ontology is implemented in the Protégé ontology tool. As illustrated by the case study, our approach enables better formalization and inferencing, thanks to OWL-DL. The ontology may also be used to represent OLAP cubes on the semantic Web (with RDF), by defining these cubes as instances of the OWL-DL multidimensional ontology.
Enhancing the cellular uptake of Py–Im polyamides through next-generation aryl turns (2011)

Pyrrole-imidazole (Py-Im) hairpin polyamides are a class of programmable, sequence-specific DNA binding oligomers capable of disrupting protein-DNA interactions and modulating gene expression in living cells. Methods to control the cellular uptake and nuclear localization of these compounds are essential to their application as molecular probes or therapeutic agents. Here, we explore modifications of the hairpin γ-aminobutyric acid turn unit as a means to enhance cellular uptake and biological activity. Remarkably, introduction of a simple aryl group at the turn potentiates the biological effects of a polyamide targeting the sequence 5'-WGWWCW-3' (W =A/T) by up to two orders of magnitude. Confocal microscopy and quantitative flow cytometry analysis suggest this enhanced potency is due to increased nuclear uptake. Finally, we explore the generality of this approach and find that aryl-turn modifications enhance the uptake of all polyamides tested, while having a variable effect on the upper limit of polyamide nuclear accumulation. Overall this provides a step forward for controlling the intracellular concentration of Py-Im polyamides that will prove valuable for future applications in which biological potency is essential.
The alpha effect. A review (1973)

Abstract Instances of high reactivity (as signaled by a positive Brönsted deviation) by nucleophiles bearing one or more unshared pairs of electrons on an atom adjacent to the nucleophilic center (the alpha effect) are surveyed in the context of possible explanations for this phenomenon. No single cause appears to account satisfactorily for all the data. However, four factors (ground‐state destabilization of the nucleophile, transition‐state stabilization, solvent effect differences for alpha and nonalpha nucleophiles, and product stability) may be involved in contributory roles. The response to proton basicity of a substrate is probably not related to its susceptibility to the alpha effect. Carbon electrophiles seem to be receptive to the alpha effect in the order digonal > trigonal > tetrahedral. The inconsistent behavior of alpha nucleophiles makes the prediction of alpha effects rather risky and confirms the complicated nature of nucleophilic substitutions.
Adaptive Wireless Information Systems (1994)

We provide an architecture for future wireless information services as a collection of autonomous cells which offer information services of widely varying geographic scope. Each MSS (Mobile Support Station) has the freedom to decide how to allocate different information services to its bandwidth and in which form to offer them. Two basic forms of delivery of information service are identified: periodic publishing mode on a publication subchannel and on-demand mode on the on-demand subchannel. We describe, how each MSS makes the decision about which form of service delivery to use and how to structure its publication subchannel by varying the frequency of publication of individual data items depending on the frequency of requests. In this way, we improve the packet efficiency and power efficiency of the client-server protocols by maximizing the number of queries per Hz and queries per Watt. Each mobile client has to be able to interoperate in this environment. This is assured by making cells self-explanatory about their service allocation. We describe how the presented concepts can be implemented by proposing an extension of WWW protocol, called adaptive WWW. We also show how to implement the proposed protocol along the lines of CDPD.
Preadmission strategies: reducing the length of preoperative stay. (1996)

Pursuing efficiency, the Ottawa Civic Hospital implemented a preadmission program which moved as much of the surgical admission procedure as possible to a single preadmission visit. The authors describe the process of researching, planning and implementing the program. They also report the savings it has represented for the hospital and the reaction from surgical patients.
[Surgical correction of severe maxillary hypoplasia secondary to the repairment of congenital cleft palate]. (2009)

The severe maxillary hypoplasia in cleft lip and palate patients can be successfully corrected with DO and orthognathic surgical procedures. The long-term skeletal stability was satisfactory.
Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties. (1989)

A human parathyroid-like protein (PLP) has recently been isolated and cloned from human tumors associated with the paraneoplastic syndrome, humoral hypercalcemia of malignancy. PLP shares NH2-terminal amino acid sequence similarity with PTH but has a unique primary structure thereafter. Studies reported to date have indicated that both native and synthetic amino-terminal PLP polypeptides display actions in vivo and in vitro that are similar to those of PTH. We report here that purified native PLP and synthetic 36Tyr(1-36)amide human PLP induce epidermal growth factor-dependent transformation of NRK 49F cells in soft agar. Further, the synthetic peptide induces a significant increase in the biosynthesis of fibronectin by human dermal fibroblasts. (1-34)PTH does not display either of these biological activities. These data indicate that there are qualitative differences between PTH and the recently identified PLP. The latter hormone appears to possess transforming growth factor-like properties that may be relevant to its physiological actions.
Remote supervision for intelligent circuit breakers and gas insulated substations (2008)

The advancement of asset management techniques was significantly improved by the development of processes controlled by microprocessors. Using reliable and expert monitoring systems that are now available, utilities can further increase the availability of their transmission grid, in optimizing maintenance practice and to extend the useful life of the transmission network equipment. This paper describes the hardware architecture of the state-of-the-art monitoring equipment from the simplest to the most elaborate, including UHF partial discharge detection system for gas insulated switchgear (GIS). This last piece of equipment is considered as the best way to ensure that dielectric integrity of GIS equipment is respected during its lifetime. Strategies to implement these tools in the substation, both on-line and off-line, are also discussed. The impact of last-generation devices, adding protection and control to monitoring, coupled with the introduction of long awaited substation communication protocol IEC 61850 is detailed. Substations are not always controlled locally. Maintenance teams are sometimes located in areas far away from the substations. In such cases, it is important to facilitate remote access to the data recorded on the monitoring system and get a quick status of the GIS installation. Such facility is permitted with modern digital monitoring systems. Customers can get access to the same type of information as provided locally using a remote HMI. This is possible via intranet, internet or telephone network. The information can also be accessed remotely from manufacturer facilities upon customer request, and first hand remote diagnosis or maintenance recommendations can be provided by factory experts.
Long-Term Heart Rate Reduction Induced by the Selective <i>I</i> <sub>f</sub> Current Inhibitor Ivabradine Improves Left Ventricular Function and Intrinsic Myocardial Structure in Congestive Heart Failure (2004)

In rats with CHF, long-term HRR induced by the selective I(f) inhibitor ivabradine improves LV function and increases stroke volume, preserving cardiac output despite the HRR. The improvement of cardiac function is related not only to the HRR per se but also to modifications in the extracellular matrix and/or function of myocytes as a consequence of long-term HRR.
Political evolution of EMAS: Perspectives from the EU, national governments and industrial groups (1995)

Abstract The adoption of the eco‐management and audit scheme (EMAS) in 1993 by the Council of Ministers was preceded by controversial debates. The European Commission presented EMAS in 1990 as a mandatory scheme. Industry responded in unison and rejected the compulsory nature of the scheme strongly. When the Commission decided to change the scheme into a voluntary standard, the response of industry became diverse. Industry in general welcomed EMAS as it saw it as a means to improve its image; German industry, however, continued to oppose the scheme. Its criticism was that the scheme did not take into account different emission standards which have to be achieved in different countries. Another important reason was that the management‐oriented scheme does not correspond well to the German approach to handling environmental problems. German companies are more technology‐oriented. An active advocate of EMAS was the UK. As the UK had taken the lead on environmental management systems and environmental auditing, it was keen to push these concepts throughout Europe.