gebhart/patrepeval huggingface dataset:
Nonblocking copy networks for multicast packet switching (1988)

In addition to handling point-to-point connections, a broadband packet network should be able to provide multipoint communications that are required by a wide range of applications. The essential component to enhance the connection capability of a packet network is a multicast packet switch, capable of packet replications and switching, which is usually a serial combinations of a copy network and a point-to-point switch. The copy network replicates input packets from various sources simultaneously, after which copies of broadcast packets are routed to their final destination by the switch. A nonblocking, self-routing copy network with constant latency is proposed. Packet replications are accomplished by an encoding process and a decoding process. The encoding process transforms the set of copy numbers, specified in the headers of incoming packets, into a set of monotone address intervals which form new packet headers. The decoding process performs the packet replication according to the Boolean interval splitting algorithm through the broadcast banyan network, the decision making is based on a two-bit header information. This yields minimum complexity in the switch nodes.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Preliminary face recognition grand challenge results (2006)

The goal of the Face Recognition Grand Challenge (FRGC) is to improve the performance of face recognition algorithms by an order of magnitude over the best results in Face Recognition Vendor Test (FRVT) 2002. The FRGC is designed to achieve this performance goal by presenting to researchers a six-experiment challenge problem along with a data corpus of 50,000 images. The data consists of 3D scans and high resolution still imagery taken under controlled and uncontrolled conditions. This paper presents preliminary results of the FRGC for all six experiments. The preliminary results indicate that significant progress has been made towards achieving the stated goals. 1.
SOME GRAPHITE LAMELLAR STRONG AND SUPER ACIDS AS CATALYSTS IN THE ISOMERIZATION AND CLEAVAGE REACTIONS OF PENTANE AND HEXANE (1981)

Abstract Graphite lamellar catalysts of acids; SbF5, SbF5–HF and AlBr3–Br2 were found to be effective for the isomerization and cleavage reactions of pentane and hexane at room temperature. Graphite-SbF5–HF catalyst was excellent and gave skeletal isomerization products exclusively from pentane and hexane. Graphite-AlBr3–Br2 catalyst showed a highly catalytic activity to yield C4∼C7 alkanes which were formed via the β-cleavage reaction of oilgomeric alkyl cations derived from starting alkanes. Graphite-SbF5catalyst exhibited catalytic behavior and gave skeletal isomerization products exclusively for pentane but gave C4∼C7 alkanes as the major products for hexane.
Inflammatory joint disease: the role of cytokines, cyclooxygenases and reactive oxygen species. (1996)

Cytokines are known to have a key role in the onset and development of inflammatory joint disease, including rheumatoid arthritis and osteoarthritis. The effects of some cytokines on the cells and tissues involved in inflammation of the joint are well catalogued, but recent discoveries of new cytokines, and interest in intracellular signalling molecules, have thrown new light on the way in which cytokines mediate the cellular responses that lead to inflammation. Here, recent work on the roles of cytokines, cyclooxygenases, nitric oxide and other reactive oxygen species, in the cellular pathways that lead from cytokine receptor to inflammation, are discussed.
IP-Based IoT Device Detection (2018)

Recent IoT-based DDoS attacks have exposed how vulnerable the Internet can be to millions of insufficiently secured IoT devices. To understand the risks of these attacks requires learning about these IoT devices---where are they, how many are there, how are they changing? In this paper, we propose a new method to find IoT devices in Internet to begin to assess this threat. Our approach requires observations of flow-level network traffic and knowledge of servers run by the manufacturers of the IoT devices. We have developed our approach with 10 device models by 7 vendors and controlled experiments. We apply our algorithm to observations from 6 days of Internet traffic at a college campus and partial traffic from an IXP to detect IoT devices.
Voltage dip compensation in LV networks using distributed energy resources (2005)

The paper presents possibilities of using distributed generation (DG) sources to mitigate voltage dips in LV grids due to short circuits in the MV and HV network. DG sources based on voltage source inverters (VSI) with pulse width modulation (PWM) control were considered. The DG sources generate active power depending on the depth of voltage dips under faults conditions. The compensation effect is shown for different DG source capabilities and different coupling between the LV and MV networks, i.e. the short circuit power of the distribution transformer. The PSCADIEMTDC programme was used for analysis of system performance. Results of simulation for a study network are presented, which show the effectiveness of compensation.
Studies on the Catalytic Mechanism of Five DNA Glycosylases (1995)

DNA glycosylases catalyze scission of the N-glycosylic bond linking a damaged base to the DNA sugar phosphate backbone. Some of these enzymes carry out a concomitant abasic (apyrimidinic/apurinic(AP)) lyase reaction at a rate approximately equal to that of the glycosylase step. As a generalization of the mechanism described for T4 endonuclease V, a repair glycosylase/AP lyase that is specific for ultraviolet light-induced cis-syn pyrimidine dimers, a hypothesis concerning the mechanism of these repair glycosylases has been proposed. This hypothesis describes the initial action of all DNA glycosylases as a nucleophilic attack at the sugar C-1' of the damaged base nucleoside, resulting in scission of the N-glycosylic bond. It is proposed that the enzymes that are only glycosylases differ in the chemical nature of the attacking nucleophile from the glycosylase/AP lyases. Those DNA glycosylases, which carry out the AP lyase reaction at a rate approximately equal to the glycosylase step, are proposed to use an amino group as the nucleophile, resulting in an imino enzyme-DNA intermediate. The simple glycosylases, lacking the concomitant AP lyase activity, are propose to use some nucleophile from the medium, e.g. an activated water molecule. This paper reports experimental tests of this hypothesis using five representative enzymes, and these data are consistent with this hypothesis.
Heterogeneous catalytic ring opening polymerization of 2,2-dimethyltrimethylene carbonate with metal alkoxides as initiators in protic conditions (1999)

The polymerization of 2,2-dimethyltrimethylene carbonate (DTC) by using new heterogeneous systems as initiators has been investigated. These systems are obtained by grafting various Lewis acid metal alkoxides belonging to group IIb (Zn), IIIa (Al), IIIb (Y and Nd) as well as IVb (Ti and Zr) on porous solids (silica, alumina and zinc oxide). Adding alcohol in excess to the reaction mixture induces a transfer reaction which allows to synthesise functionalized polycarbonates. In most cases, the degree of polymerization is controlled by the [monomer]/[alcohol] ratio. It was found that the activity depends both on the metal and on the solid support. Y alkoxides offer the best activities while those belonging to group IVb are less efficient. The porous solid acts as a chemical ligand rather than only as a mechanical support of the active centres.
Growth Hormone Stimulates the Tyrosine Phosphorylation and Association of p125 Focal Adhesion Kinase (FAK) with JAK2 (1998)

We have demonstrated that growth hormone (GH) activates focal adhesion kinase (FAK), and this activation results in the tyrosine phosphorylation of two FAK substrates, paxillin and tensin. The activation of FAK is time-dependent (maximal activation at 5-15 min) and dose-dependent (maximal activation at 0.05 nM). FAK and paxillin are constitutively associated in the unstimulated state, remain associated during the stimulation phase, and recruit tyrosine-phosphorylated tensin to the complex after GH stimulation. Half of the carboxyl-terminal region of the GH receptor is dispensable for FAK activation, but FAK activation does require the proline-rich box 1 region of the GH receptor, indicative that FAK is downstream of JAK2. FAK associates with JAK2 but not JAK1 after GH stimulation of cells. Using FAK-replete and FAK-deficient cells, we also show that FAK is not required for STAT-mediated transcriptional activation by GH. The use of FAK in the signal transduction pathway utilized by GH may be central to many of the pleiotropic effects of GH, including cytoskeletal reorganization, cell migration, chemotaxis, mitogenesis, and/or prevention of apoptosis and gene transcription.
Tracking an unknown time-varying number of speakers using TDOA measurements: a random finite set approach (2006)

Speaker location estimation techniques based on time-difference-of-arrival measurements have attracted much attention recently. Many existing localization ideas assume that only one speaker is active at a time. In this paper, we focus on a more realistic assumption that the number of active speakers is unknown and time-varying. Such an assumption results in a more complex localization problem, and we employ the random finite set (RFS) theory to deal with that problem. The RFS concepts provide us with an effective, solid foundation where the multispeaker locations and the number of speakers are integrated to form a single set-valued variable. By applying a sequential Monte Carlo implementation, we develop a Bayesian RFS filter that simultaneously tracks the time-varying speaker locations and number of speakers. The tracking capability of the proposed filter is demonstrated in simulated reverberant environments
Passive alignment of second generation optoelectronic devices (1997)

This paper details how expanded-mode semiconductor devices and passive alignment techniques can be used to realize low-cost high-performance fiber grating laser and laser amplifier packages for future generations of optical telecommunication systems.
Sulforaphane and 2-oxohexyl isothiocyanate induce cell growth arrest and apoptosis in L-1210 leukemia and ME-18 melanoma cells (2003)

Flow cytometry and laser-scanning confocal microscopy were used to study the effect of sulforaphane (SFN) and 2-oxohexyl isothiocyanate on the growth and viability of mouse leukemia L-1210 and human melanoma ME-18 cells during their exponential growth. Sulforaphane belongs to a group of compounds known as isothiocyanates. Isothiocyanates mainly occur in Cruciferous family. In particular, they occur in many vegetables such as broccoli and their sprouts. SFN and 2-oxohexyl isothiocyanate are potent inducers of detoxication phase 2 enzymes in mouse tissues and murine hepatoma cells in culture. Sulforaphane was shown to induce cell growth arrest in a dose dependent manner, followed by cell death. Sulforaphane induced the cell death via an apoptotic process. Two markers of apoptosis were investigated: phosphatidylserine externalization, which occurs in the early stages of apoptosis, and DNA strand breaks. Our results strongly suggest of chemopreventive activity toward cancer by the induction of apoptosis by SFN and 2-oxohexyl isothiocyanate.
Kinetics of Precipitation of Cellulose from Cellulose−NMMO−Water Solutions (2005)

The regeneration of a solid, crystallized cellulose solution in a N-methylmorpholine-N-oxide (NMMO)-water mixture was studied by measuring the diffusion coefficient of both the water uptake from the regenerating bath and the NMMO outflow to this bath. The diffusion coefficient of water going to the cellulose solution is about 10 times larger than the diffusion coefficient of NMMO leaving the solution. This difference expresses the strongly hygroscopic character of NMMO. None of these coefficients depends on cellulose molecular weight showing that no major rearrangement of cellulose chains occurs at the beginning of the regeneration. The diffusion coefficient of water is not influenced by the cellulose concentration, whereas the diffusion coefficient of NMMO decreases strongly when the cellulose concentration increases. Extrapolating the diffusion coefficient of NMMO versus cellulose concentration to zero shows that the maximal concentration of cellulose in NMMO-water is about 15%. Above this value, undissolved cellulose should be present. From the influence of the NMMO content in the water regenerating bath, it is possible to see that NMMO is removed from the solution if the bath has a NMMO content lower than 60%, to be compared with the 80% NMMO concentration in the solution.
Deformation Measurements and Material Property Estimation of Mouse Carotid Artery Using a Microstructure-Based Constitutive Model (2010)

A series of pressurization and tensile loading experiments on mouse carotid arteries is performed with deformation measurements acquired during each experiment using three-dimensional digital image correlation. Using a combination of finite element analysis and a microstructure-based constitutive model to describe the response of biological tissue, the measured surface strains during pressurization, and the average axial strains during tensile loading, an inverse procedure is used to identify the optimal constitutive parameters for the mouse carotid artery. The results demonstrate that surface strain measurements can be combined with computational methods to identify material properties in a vascular tissue. Additional computational studies using the optimal material parameters for the mouse carotid artery are discussed with emphasis on the significance of the qualitative trends observed.
Tectonic evolution of Syria Interpreted from Integrated Geophysical and Geological Analysis (2001)

Copyright 2001, Graham Brew. See also: http://atlas.geo.cornell.edu/syria/brew_dissertation2001.htm
[Study on Trichosanthin induced apoptosis of leukemia K562 cells]. (1998)

Trichosanthin (TCS), an eukaryotic ribosome-inactivating protein isolated from the root tuber of Trichosanthes plant, has various biological activities including abortion induction, antitumor, and anti-HIV. In this study, cultured human leukemia K562 cells treated with trichosanthin were examined. Analysis of the cells by single laser flow cytometry showed the sub-G1 peak. DNA extracted from these cells formed a characteristic "ladder" on agarose gel electrophoresis. Under electromicroscope, typical morphological changes of apoptosis were also observed. From all of these findings, we concluded that trichosanthin was able to induce apoptosis in K562 cells.
PP/clay nanocomposites: Effect of clay treatment on morphology and dynamic mechanical properties (2001)

Abstract The morphology and properties of polypropylene (PP)/clay nanocomposites are described. The melt intercalation of organophilic clay was carried out with a single‐screw extruder. The effects of two kinds of treatments of clay are discussed. Maleic anhydride (MAH)‐grafted PP was used as a compatibilizer. The expansion of the intergallery distance of the clay was governed by the interaction between the clay treatment and the compatibilizer. In one case, the composites exhibited significantly reduced intensities of diffraction peaks, suggesting partial exfoliation of the clay layers, whereas for the second clay sample, expansion of the gallery height was noted. The mechanical properties of the PP/clay composites showed significant enhancement in their mechanical and thermal properties. About a 35% increase in the tensile modulus and about a 10% increase in the tensile strength were observed. The thermal degradation temperature increased from 270 to about 400°C as a result of the incorporation of clay, and the extent depended on the dispersion of clay in the composite. The most interesting outcome of this study was the changes in morphology for PP/clay composites, which are reported here for the first time. An optical microscopic study revealed that the PP/clay composites could be crystallized at higher temperatures than pure PP and that the morphology was remarkably altered because of the presence of layers of clay. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 81: 1786–1792, 2001
Chain transfer in ethylene polymerization (1966)

Abstract Chain transfer constants in the homogeneous free‐radical polymerization of ethylene at 1360 atm. and 130°C. have been determined for over 50 compounds, including nearly 300 hydrocarbons. The effects of substitution, unsaturation, and ring strain in the transfer agent molecule on the reactivity of its CH bonds in chain‐transfer reactions with a polyethylene growing chain are analyzed. Qualitatively, these trends parallel those found for simple radicals attacking simple molecules. However, the principle that the reactivity of a compound is the sum of the reactivities of all reactive bonds, which is well established for simple radicals and transfer agents, is found not to be true in ethylene polymerization. It is postulated that the deviations from this principle are due to steric factors which become very important when the free radical is bulky. The transfer constants measured in ethylene polymerization are also compared with transfer constants in other systems. A strong correlation is found between the transfer constants in ethylene and published data on rates of abstraction of hydrogen atoms by methyl radicals.
Bradykinin stimulates the ERK→Elk-1→Fos/AP-1 pathway in mesangial cells (1998)

Among its diverse biological actions, the vasoactive peptide bradykinin (BK) induces the transcription factor AP-1 and proliferation of mesangial cells (S. S. El-Dahr, S. Dipp, I. V. Yosipiv, and W. H. Baricos. Kidney Int. 50: 1850-1855, 1996). In the present study, we examined the role of protein tyrosine phosphorylation and the mitogen-activated protein kinases, ERK1/2,in mediating BK-induced AP-1 and DNA replication in cultured rat mesangial cells. BK (10(-9) to 10(-7) M) stimulated a rapid increase in tyrosine phosphorylation of multiple proteins with an estimated molecular mass of 120-130, 90-95, and 44-42 kDa. Immunoblots using antibodies specific for ERK or tyrosine-phosphorylated ERK revealed a shifting of p42 ERK2 to a higher molecular weight that correlated temporally with an increase in tyrosine-phosphorylated ERK2. Genistein, a specific tyrosine kinase inhibitor, prevented the phosphorylation of ERK2 by BK. In-gel kinase assays indicated that BK-induced tyrosine phosphorylation of ERK2 is accompanied by fourfold activation of its phosphotransferase activity toward the substrate PHAS-I (P < 0.05). Furthermore, BK stimulated a 2.5-fold increase (P < 0.05) in phosphorylation of Elk-1, a transcription factor required for growth factor-induced c-fos transcription. In accord with the stimulation of Elk-1 phosphorylation, BK induced c-fos gene expression and the production of Fos/AP-1 complexes. In addition, thymidine incorporation into DNA increased twofold (P < 0. 05) following BK stimulation. Each of these effects was blocked by tyrosine kinase inhibition with genistein or herbimycin A. Similarly, antisense oligodeoxynucleotide targeting of ERK1/2 mRNA inhibited BK-stimulated DNA synthesis. In contrast, protein kinase C inhibition or depletion had no effect on BK-induced c-fos mRNA, AP-1-DNA binding activity, or DNA synthesis. Collectively, these data demonstrate that BK activates the ERK-->Elk-1-->AP-1 pathway and that BK mitogenic signaling is critically dependent on protein tyrosine phosphorylation.
Switchable mirrors of chiral liquid crystal gels (1999)

Chiral nematic liquid crystal compositions containing mono- and di-acrylates in mixtures with non-reactive liquid crystal molecules were produced. Defect-free planar macroscopic alignment of the molecules was induced between uniaxially rubbed substrates. Polymerization of the acrylate groups was initiated photochemically leading to the formation of a new class of chiral gels consisting of a lightly cross-linked network containing non-reactive molecules. In this way, the chiral pitch and, hence, the reflection colour became permanently fixed. Under the influence of an electric field the gels could be switched to the homeotropic state and reverted to the planar defect-free state upon removal of the electric field. Depending on the composition of the gel, either the position of the reflection band remained the same while its magnitude and/or width decreased, or its position shifted to smaller wavelengths with increasing electric field. Some of the gels showed sharp switching characteristics with a hysteresis making them suitable for passive matrix addressing with a high degree of multiplexability. The gels also showed fast switching times as they reverted to the defect-free optical state upon removal of the electric field. The phase structure of the gels was studied using dielectric spectroscopy which showed that the gels have an inhomogeneous structure.
“Historias, indígenas, nación y estado en el bicentenario de la independencia de la República del Paraguay (1811-2011)”, de Gabriela Dalla-Corte Caballero (coord.). (2012)

“Stories, natives, nation and State in the bicentennial of the Republic of Paraguay (1811-2011)”, by Gabriela Dalla-Corte Caballero (coord.).
Antifolate Resistance in a HeLa Cell Line Associated With Impaired Transport Independent of the Reduced Folate Carrier (2004)

Prior studies from this laboratory documented the prevalence of methotrexate (MTX) transport activity with a low pH optimum in human solid tumor cell lines. In HeLa cells, this low pH activity has high affinity for pemetrexed [PMX (Alimta)] and is reduced folate carrier (RFC)-independent because it is not diminished in a RFC-null subline (R5). R5 cells also have residual transport activity, with high specificity for PMX, at neutral pH. In the current study, a R5 subline, R1, was selected under MTX selective pressure at a modest reduction in pH. There was markedly decreased MTX and PMX transport at both pH 5.5 and pH 7.4. When MTX was removed, there was a slow return of transport activity, and when MTX was added back, there was loss of transport at both pH values within 8 weeks. In R1 cells, there was a marked decrease in accumulation of PMX, MTX, and folic acid along with a decrease in growth inhibition by these and other antifolates that require a facilitative process to gain entry into cells. These data demonstrate that (i) RFC-independent transport in HeLa cells at low and neutral pH contributes to antifolate activity (in particular, to PMX activity) and can be diminished by antifolate selective pressure and (ii) the loss of these activities results in marked resistance to PMX, an agent for which there is little or no loss of activity when transport mediated by RFC is abolished. These observations suggest that transport activity in RFC-null HeLa R5 cells at neutral and low pH may reflect the same carrier-mediated process.
Spatially Resolved PMD Measurements (2004)

Spatially resolved measurements of polarization properties of fiber optic link-such as birefringence, polarization-mode dispersion (PMD) and polarization dependent loss (PDL)-may be effectively performed using polarization sensitive reflectometric techniques. In particular, this paper focuses on polarization-OTDR and reviews its theory and applications. Special emphasis is given to the use of optical reflectometry as a tool to characterize fiber birefringence. This allows to inspect the fiber while cabled and, consequently, to test and improve the cabling process. In addition, it also allows to define reliable mathematical models, which are essential for the design of low polarization mode dispersion fibers. The application of polarization-OTDR to polarization mode dispersion and polarization dependent loss measurements is also discussed.