gebhart/patrepeval huggingface dataset:
Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells (1987)

Primary cultures of cerebellar granule cells have been used in pharmacologically and functionally characterizing excitatory amino acid recognition sites coupled with guanylate cyclase. When granule cells were incubated in physiological culture conditions (Locke's solution, pH 7.4), only kainate and, to a lesser extent, L-glutamate increased cyclic GMP (cGMP) levels. Under these conditions, L-aspartate, N-methyl-D-aspartate (NMDA), and quisqualate were inactive. When granule cells were incubated in the absence of extracellular Mg2+ or in the presence of the depolarizing agent veratrine, L-glutamate, L-aspartate, and NMDA became as effective as kainate in enhancing cGMP formation. The action of kainate was preferentially antagonized by 2,3-cis-piperidindicarboxylate, whereas the action of L-glutamate was preferentially antagonized by (+/-)2-amino-5-phosphonovalerate. These data suggest that 2 different excitatory amino acid recognition sites (activated by kainate or by L-glutamate, L-aspartate, and NMDA, respectively) are coupled with guanylate cyclase in primary cultures of cerebellar granule cells: While the coupling of the recognition site for kainate with guanylate cyclase operates under resting conditions and in the presence of Mg2+, the coupling of the recognition site for L-glutamate, L-aspartate, and NMDA with guanylate cyclase requires depolarizing conditions or the absence of extracellular Mg2+.
Balloon Dilatation of the Prostate: Technique and Early Results (1990)

Fourteen men with outflow obstruction were treated by balloon dilatation of the prostatic urethra using 25 and 30 mm balloon catheters. Significant improvement in objective measurement of outflow obstruction was noted in only 2 patients.
Digital carry applied to successive approximation digital voltmeters (1970)

Successive approximation encounters difficulties, when used in high resolution voltmeters, due to the settling time of the decision loop. Solutions so far have either slowed the reading rate, or have significantly increased complication and cost. Digital carry solves the problem both simply and inexpensively. It is applied to a voltmeter which, at 50 readings per second, has a scale length of 100,000.
Synthesis of the retro-inverso peptide analogues of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) (2001)

Two novel retro-inverso analogues of a conformationally restricted carbocyclic muramyl dipeptide (MDP) derivative N-(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2carbonyl)-L-alanyl-D-isoglutamine were prepared and tested in a immunorestoration test in mice. Both retro-inverso MDP analogues did not enhance non-specific resistance to experimental fungal infection in immunosuppressed animals, suggesting that the intact amide bond is essential for the immunorestorating activity in this type of rigidified carbocyclic MDP analogues.
[Resveratrol inhibits EGF-induced invasion of human lung adenocarcinoma A549 cells]. (2010)

Invasion and metastasis are the primary causes of death in patients with pulmonary carcinoma. The epidermal growth factor (EGF) stimulates A549 cells invasion greatly through activating ERK and PI3K-Akt signaling pathway. The aim of this study is to elucidate the inhibitory effect of Resveratrol on EGF-induced invasive ability of A549 cells in vitro and explore the molecular mechanism.The cytotoxicity of Resveratrol was evaluated by methyl thiazolyltetrazolium (MTT) assay. Then, the A549 cells were treated with EGF and non-cytotoxic concentration of Resveratrol. The cells' invasion were detected by Boyden chamber assay; MMP-2 activity was determined by gelatine zymography assay; the changes of the related proteins were detected by Western blot.Resveratrol was not toxic to A549 cells at the concentration between 0 to 30 microM. The invasion ability of EGF-induced A549 cells was decreased after treatment with 20 microM resveratrol for 24 h, accompanied by the inhibition of MMP-2 secretion. And the levels of p-ERK1/2, PI3K (within 6 h) were suppressed too.20 microM Resveratrol inhibits A549 cells' invasion possibly through the suppression of the activation of ERK and PI3K-Akt signaling pathways, subsequently exerting inhibitory effect on MMP-2.
Dry Anaerobic Conversion of Municipal Solid Waste by Means of the Dranco Process (1992)

The Dranco process has been developed for the conversion of solid organic wastes, specifically the organic fraction of municipal solid waste (MSW), to energy and a humus-like final product, called Humotex. The Dranco process can be compared to landfill gas production, accelerated by a factor 1000. A Dranco installation with a digester of 808 m3 treating 10,500 tons of source separated waste per year will be constructed in 1991 at Brecht, Belgium. A description of the plant is elaborated. A demonstration plant of 56 m3 has been in operation for several years in Gent, Belgium using mixed garbage as a feedstock. The operating temperature in the digester is 55°C and the total solids concentration is ca. 32%. The mean gas production rate is 3.33 Nm3 CH4/m3reactor.day. The volumetric loading is 17.3 kg COD/m3reactor.day and the COD reduction is 55%. The gas production process is finalized in 3 weeks. The final product is dewatered and further stabilized in a 10 day aerobic post-treatment. The Humotex is free of pathogens. Low concentrations of heavy metals can only be obtained through separate collection of garbage. The Dranco process then also focusses on the digestion of source separated waste such as vegetable, fruit, garden and non-recyclable paper waste.
The comparative assessment of paraspinal tissue compliance in asymptomatic female and male subjects in both prone and standing positions. (1991)

Segmental bilateral paraspinal tissue compliance measures were obtained from 50 male and 50 female asymptomatic subjects (vertebral segments C7-L5). Interexaminer concordance for the taking of the measure was found to be extremely high (r greater than .90). Additionally, test-retest measures obtained from the same subjects initially, and again 15 min or 2 wk later indicated fairly low short-term as well as long-term temporal variabilities for the measure. The greatest levels of variability were encountered at lumbar segments, particularly with 2 wk intervals between assessments, and when measures were obtained with subjects in the standing, rather than prone, position. Data generated by this study suggest that tissue compliance assessments may provide useful information with respect to the contractile state of the paraspinal musculature at various regions or segmental levels.
Influence of Mn Doping on Ferroelectric-Antiferromagnet BiFeO<sub>3</sub> Thin Films Grown on (LaAlO<sub>3</sub>)<sub>0.3</sub>(Sr<sub>2</sub>AlTaO<sub>6</sub>)<sub>0.7</sub> Substrates (2006)

We have fabricated phase-pure BiFe1-xMnxO3 (x=0, 0.05, and 0.2) thin films on (LaAlO3)0.3(Sr2AlTaO6)0.7 substrates by pulsed laser deposition technique and examined the Mn substitution effect on the electric and magnetic properties. The undoped BiFeO3 films exhibited simultaneous ferroelectricity and antiferromagnetism at room temperature, which was consistent with the bulk property. The increase in Mn content resulted in an enhancement in electric conductivity, leading to an increase in spontaneous magnetization at room temperature along with a deterioration in ferroelectricity. Among the three compositions, BiFe1-xMnxO3 (x=0.05) thin film showed the best multiferroic property exhibiting simultaneous ferroelectricity and weak ferromagnetism.
Viewpoint selection for vision systems in industrial inspection (2014)

An automatic method for solving the problem of view planning in high-resolution industrial inspection is presented. The method's goal is to maximize the visual coverage, and to minimize the number of cameras used for inspection. Using a CAD model of the object of interest, we define the scene-points and the viewpoints, with the later being the solution space. The problem formulation accurately encapsulates all the vision- and task-related requirements of the design process for inspection systems. We use a graph-based approach to formulate a solution for the problem. The solution is implemented as a greedy algorithm, and the method is validated through experiments.
Capsular opacification after cataract surgery and capsule (1998)

The lens capsule, the keystone of modern cataract surgery, has been the subject of some important and interesting investigations over the past year. This review addresses 1) inhibition of posterior capsule opacification (surgical techniques, intraocular lens design, and pharmacologic methods); 2) treatment of posterior capsule opacification; and 3) characteristics of the capsule. Of special interest are techniques for inhibiting posterior capsule opacification in pediatric patients by optic capture through a posterior capsulorhexis, the concept that sharp optic edges markedly decrease posterior capsule opacification as compared with round-edged implants, and promising work demonstrating that an immunotoxin may be effective in prevention of posterior capsule opacification.
A Short History of Photography (1972)

Journal Article A Short History of Photography Get access Walter Benjamin Walter Benjamin Search for other works by this author on: Oxford Academic Google Scholar Screen, Volume 13, Issue 1, Spring 1972, Pages 5–26, https://doi.org/10.1093/screen/13.1.5 Published: 01 March 1972
The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized (1999)

The sigma subunit of eubacterial RNA polymerase is required throughout initiation, but how it communicates with core polymerase (alpha(2)betabeta') is poorly understood. The present work addresses the location and function of the interface of sigma with core. Our studies suggest that this interface is extensive as mutations in six conserved regions of sigma(70) hinder the ability of sigma to bind core. Direct binding of one of these regions to core can be demonstrated using a peptide-based approach. The same regions, and even equivalent residues, in sigma(32) and sigma(70) alter core interaction, suggesting that sigma(70) family members use homologous residues, at least in part, to interact with core. Finally, the regions of sigma that we identify perform specialized functions, suggesting that different portions of the interface perform discrete roles during transcription initiation.
Algorithms for computing isogenies between elliptic curves (1997)

The efficient implementation of Schoof's algorithm for computing the cardinality of elliptic curves over finite fields requires the computation of isogenies between elliptic curves. We make a survey of algorithms used for accomplishing this task. When the characteristic of the field is large, P-Weierstrass's functions can be used. When the characteristic of the field is small, we now have three algorithms at our disposal, two due to Couveignes and one to the first author. We treat the same example using these three algorithms and make some comparisons between them.
Using a calorimeter and spectrometer to measure radiant efficiencies of infrared sources (1986)

The radiant efficiency of a heater is observed to decrease when an intervening window is used to protect the infrared source. A power balance equation is used to calculate the theoretical radiant efficiency, defined as the fraction of electrical power into the heater emitted as infrared radiation. The calculations are based on measured temperatures of the different heater faces and indicate the losses are mostly due to convective losses from the heater face and top panel. A spectrometer measures the spectral radiance emitted from the heater. The area under the spectral radiance curve gives a second estimate for the radiant efficiency. A large calorimeter is described which directly measures the emitted infrared radiation from the heater’s face. Finally, the surface temperatures of the different window materials are measured and compared with calculated values.
A Low-Power CMOS Front-End for Photoplethysmographic Signal Acquisition With Robust DC Photocurrent Rejection (2008)

A micro-power CMOS front-end, consisting of a transimpedance amplifier (TIA) and an ultralow cutoff frequency lowpass filter for the acquisition of photoplethysmographic signal (PPG) is presented. Robust DC photocurrent rejection for the pulsed signal source is achieved through a sample-and-hold stage in the feed-forward signal path and an error amplifier in the feedback path. Ultra-low cutoff frequency of the filter is achieved with a proposed technique that incorporates a pair of current-steering transistors that increases the effective filter capacitance. The design was realized in a 0.35-mum CMOS technology. It consumes 600 muW at 2.5 V, rejects DC photocurrent ranged from 100 nA to 53.6 muA, and achieves lower-band and upper-band - 3-dB cutoff frequencies of 0.46 and 2.8 Hz, respectively.
Impact of MU EDCA Channel Access on IEEE 802.11ax WLANs (2019)

To achieve increased radio utilization in dense WLAN deployments, IEEE 802.11ax amendment introduces Orthogonal Frequency Division Multiple Access (OFDMA) to the Wi-Fi standard. As the Access Point (AP) initiates the uplink OFDMA operation via a trigger, this operation provides an additional means for the STAs to gain medium access. Consequently, to retain fairness in the network and reduce contention, a novel MU EDCA channel access mode has been introduced in 802.11ax standard to temporarily deprioritize medium access for STAs participating in uplink OFDMA operation. In this paper, we implement the key components of 802.11ax OFDMA operation in custom ns-3 network simulator and evaluate the impact of MU EDCA channel access mode on 802.11ax dense WLAN performance under various network and traffic conditions. Our results show that (a) temporarily switching to MU EDCA channel access mode significantly improves network performance in terms of throughput and real-time application latency (b) the duration of temporary switch to MU EDCA channel access mode has negligible impact on network performance and (c) 200 ms of MU EDCA channel access mode can potentially support a dense network of almost 2000 STAs.
Online rotor resistance estimation using the transient state under the speed sensorless control of induction motor (2000)

In the speed sensorless control of the induction motor, the machine parameters (especially rotor resistance R/sub 2/) have a strong influence on the speed estimation. It is known that the simultaneous estimation of the rotor speed and R/sub 2/ is impossible in the slip frequency type vector control, because the rotor flux is constant. But the rotor flux is not always constant in the speed transient state. In this paper, the R/sub 2/ estimation in the transient state without signal injection to the stator current is proposed. This algorithm uses the least mean square algorithm and the adaptive algorithm, and it is possible to estimate R/sub 2/ exactly. This algorithm is verified by the digital simulations and experiments.
Quantum entangled radar theory and a correction method for the effects of the atmosphere on entanglement (2009)

A quantum entangled radar uses entangled photons instead of separate photons. It has been shown that for quantum entangled interferometers that the value of quantum entanglement deteriorates in an environment with attenuation. This paper introduces a correction method that allows the quantum radar to maintain excellent performance even when dealing with an environment with attenuation. The correction method is analogous to techniques used in adaptive optics to improve images. Correction approaches based on signal sources deliberately introduced into the environment and electromagnetic sources already present in the environment are considered. Closed form expressions for estimating the range error are derived for the cases when the radar uses N entangled photons for imaging or N separate imaging photons. Simulations of radar range error estimates for entangled and separate photon cases for propagation media with widely varying attenuation properties are provided. Comparisons of estimates with and without atmospheric correction are given. The atmospheric correction method extends the range of the beneficial effects of entanglement by a factor of 82, i.e. to 5000 km for a slowly varying propagation medium. For a propagation medium with 50 times as much variation, the atmospheric correction method offers super sensitivity for three times the range of the uncorrected case.
Automated Analytical Methods to Support Visual Exploration of High-Dimensional Data (2010)

Visual exploration of multivariate data typically requires projection onto lower dimensional representations. The number of possible representations grows rapidly with the number of dimensions, and manual exploration quickly becomes ineffective or even unfeasible. This paper proposes automatic analysis methods to extract potentially relevant visual structures from a set of candidate visualizations. Based on features, the visualizations are ranked in accordance with a specified user task. The user is provided with a manageable number of potentially useful candidate visualizations, which can be used as a starting point for interactive data analysis. This can effectively ease the task of finding truly useful visualizations and potentially speed up the data exploration task. In this paper, we present ranking measures for class-based as well as non-class-based scatterplots and parallel coordinates visualizations. The proposed analysis methods are evaluated on different data sets.
FEDOS: A Finite Element Database for Offshore Structures (1985)

Large-scale finite-element structural models demand excessive human and computer resources. FEDOS is an attempt to establish effective methods for managing the large volumes of data associated with the finite-element analysis of large offshore structures. Unlike other general-purpose structural analysis systems that are commercially available, FEDOS is unique in its use of a well-proven Database Management System to manage its database. This paper describes the development of FEDOS and its benefits to engineering users.
The Guanosine 3′,5′‐Bis(diphosphate) (ppGpp) Cycle (1979)

The metabolism of guanosine 3′,5′‐bis(diphosphate) (ppGpp) has been studied in a number of different microbial species including Escherichia coli, Bacillus stearothermophilus, Bacillus subtilis and Bacillus brevis. The results can be summarized as follows. 1. Generally, in the E. coli and B. subtilis systems, a stringent factor catalyses the ppGpp‐synthesizing reaction only when activated by uncharged tRNA codon‐specifically bound to ribosomes. In the B. stearothermophilus and B. brevis systems the stringent factor does not require activation by ribosomes. The physiological significance of this is reflected by the subcellular distribution: stringent factors requiring ribosomes for activity are exclusively found in ribosomal fractions, while those functioning independently of ribosomes are preferentially present in the high‐speed supernatant fraction. Formation of ppGpp is quite specific in that neither ATP as pyrophosphate donor nor GDP (or GTP) as acceptor can be replaced by other nucleotides. However some nucleotides, particularly ppApp, effectively inhibit ppGpp production, while others, e.g. ppGpp or A(5′)p 4 (5′)A, are not inhibitory. 2. Degradation of ppGpp is catalyzed by a guanosine 3′,5′‐bis(diphosphate) 3′‐pyrophosphohydrolase present in the ribosomal fraction which specifically releases pyrophosphate from the 3′ position of ppGpp. The activity is apparently associated with ribosomes and, unlike stringent factor, is not completely released under low‐ionic‐strength conditions. The enzyme has a molecular weight of 65000–70000 and forms dimers and tetramers having molecular weights of 130000 and 260000, respectively. It can also be released from ribosomes by 1 M potassium acetate extraction but then is insoluble in buffers of low ionic strength except in the presence of urea. It is inhibited by tRNA regardless of whether or not ribosomes are present.
Multiple positive and negative 5' regulatory elements control the cell-type-specific expression of the embryonic skeletal myosin heavy-chain gene. (1987)

To identify the DNA sequences that regulate the expression of the sarcomeric myosin heavy-chain (MHC) genes in muscle cells, a series of deletion constructs of the rat embryonic MHC gene was assayed for transient expression after introduction into myogenic and nonmyogenic cells. The sequences in 1.4 kilobases of 5'-flanking DNA were found to be sufficient to direct expression of the MHC gene constructs in a tissue-specific manner (i.e., in differentiated muscle cells but not in undifferentiated muscle and nonmuscle cells). Three main distinct regulatory domains have been identified: (i) the upstream sequences from positions -1413 to -174, which determine the level of expression of the MHC gene and are constituted of three positive regulatory elements and two negative ones; (ii) a muscle-specific regulatory element from positions -173 to -142, which restricts the expression of the MHC gene to muscle cells; and (iii) the promoter region, downstream from position -102, which directs transcription initiation. Introduction of the simian virus 40 enhancer into constructs where subportions of or all of the upstream sequences are deleted (up to position -173) strongly increases the level of expression of such truncated constructs but without changing their muscle specificity. These upstream sequences, which can be substituted for by the simian virus 40 enhancer, function in an orientation-, position-, and promoter-dependent fashion. The muscle-specific element is also promoter specific but does not support efficient expression of the MHC gene. The MHC promoter in itself is not muscle specific. These results underline the importance of the concerted action of multiple regulatory elements that are likely to represent targets for DNA-binding-regulatory proteins.
Real-time bandwidth allocation and path restorations in SONET-based self-healing mesh networks (2002)

The authors present a scheme for optimal real-time bandwidth allocation and path restorations in a mesh network via SONET WDCS (wideband digital cross-connect system) in response to demand dynamics and to link and/or node failure(s). The scheme dynamically maximizes network throughput while ensuring full service restorability. In this process, the scheme integrates the dynamics of demand admission, bandwidth allocation, and spare capacity assignment. Since the physical network capacity is limited, not all the demand can be accommodated under the full restorability requirement. The demand which cannot be allocated under this requirement should be rejected at the network boundary. In the scheme, the optimal spare capacity assignment is just a consequence of the optimal network admission and optimal fully restorable bandwidth allocation. The authors also present an efficient parallel algorithm for optimal solution of the joint demand admission and restorable bandwidth allocation problem. The algorithm is suitable for real-time optimization in large networks.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>