gebhart/patrepeval huggingface dataset:
Airborne surveillance of water basins with hyperspectral FLS-LiDAR (2010)

The airborne FLS-Lidars are based on the method of Laser Induced Fluorescence (LIF) and aimed at the analytical remote sensing of water objects. Scanning the laser beam across the flight trajectory and recording the comprehensive LIF spectrum with hyperspectral detector per every laser pulse provide detail maps of spectral properties of the water basins. A multi-tier model for integrated environmental assessment is applied for further analysis of this information to combine the benefits of "big-picture" capability of remote sensing techniques and GIS solutions with localized on-theground environmental data gathering. In this concept far looking satellite and airborne systems provide the highest tier information. The airborne data acquisition with FLS-Lidar is considered as the middle tier characterized by vast amount of LIF data with high spatial (less than 10 m) and spectral (less than 5 nm in UV/VIS spectral ranges) resolution. The lower tier is anchored with the geographical locations of important findings detected at the middle tier. Taken water samples are analyzed with fastscreening technology of Spectral Fluorescence Signatures (SFS) giving more analytical qualitative and quantitative results. And the base tier includes detail laboratory analysis of characteristic samples selected at the lower tier. Precisely geo-referenced LIF data of hyperspectral FLS-Lidar anchored to and calibrated by the ground SFS data allows detection of pollution incidents and mapping of environmental trends over vast water systems like coastal zone, lakes and rivers.r
Computer Simulation of Dual Chamber Pacemaker Algorithms Using a Realistic Heart Model (1985)

Single and dual chamber pacing algorithms have been incorporated into a realistic computer model of cardiac electrical activation. The model enables different pacemaker algorithms to be tested, it allows prediction of their behavior, and it produces a simulated ECG record for each case. The computer model has been used to test eight different modifications of a simple DDD mode to prevent or terminate pacemaker-mediated "endless loop" tachycardia: (1) constant prolongation of the atrial channel refractory period; (2) prolongation of the atrial refractory period after a ventricular premature beat (VPB); (3) atrial pacing synchronously with a VPB; (4) simple rate control; (5) rate control in which the VA counter is not reset; (6) no ventricular pacing after an atrial premature beat; (7) rate limitation of atrial sensing; and (8) a combination of DDD and high frequency atrial stimulation modes. These modifications were tested with VPBs, atrial premature beats, atrial stimulation without capture, and accelerating sinus tachycardia. Only the pacemaker designed not to pace the ventricles following an atrial premature beat behaves satisfactorily in all four circumstances. Further possibilities for the development and use of a pacemaker-oriented computer heart model are discussed.
Distributed Coverage Maximization via Sketching (2016)

Coverage problems are central in optimization and have a wide range of applications in data mining and machine learning. While several distributed algorithms have been developed for coverage problems, the existing methods suffer from several limitations, e.g., they all achieve either suboptimal approximation guarantees or suboptimal space and memory complexities. In addition, previous algorithms developed for submodular maximization assume oracle access, and ignore the computational complexity of communicating large subsets or computing the size of the union of the subsets in this subfamily. In this paper, we develop an improved distributed algorithm for the $k$-cover and the set cover with $λ$ outliers problems, with almost optimal approximation guarantees, almost optimal memory complexity, and linear communication complexity running in only four rounds of computation. Finally, we perform an extensive empirical study of our algorithms on a number of publicly available real data sets, and show that using sketches of size $30$ to $600$ times smaller than the input, one can solve the coverage maximization problem with quality very close to that of the state-of-the-art single-machine algorithm.
Analysis of genetic polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese patients with therapy-related leukemia/ myelodysplastic syndrome and de novo acute myeloid leukemia. (2000)

Several genetic polymorphisms in metabolic activation or detoxification enzymes have been associated with susceptibility to therapy-related leukemia and myelodysplastic leukemia (TRLIMDS). We analyzed gene polymorphisms of NAD(P)H:quinone oxidoreductase (NQOl), glutathione S-tranferase (GST)-MI and -TI, and CYP3A4, the enzymes of which are capable of metabolizing anticancer drugs, in 58 patients with TRL/MDS and in 411 patients with de novo acute myeloid leukemia (AML). Homozygous Ser/Ser genotype of NQOl at codon 187, causing loss of function, was more frequent in the patients with TRLIMDS (14 of 58, 24.1%; OR = 2.62) than in those with de novo AML (64 of 411, 15.6%), and control (16 of 150, 10.6%; P = 0.002). Allelic frequencies of NQOJ were different between TRL/ MDS and de novo AML (P = 0.01). In GST-MJ and -Ti, the incidence of homologous deletion was similar among the three groups. The polymorphism of the 5' promoter region of CYP3A4 was not found in persons of Japanese ethnicity. These results suggest that the NQOJ polymorphism is significantly associated with the genetic risk of TRLIMDS.
A mathematical programming approach for supplier selection using Activity Based Costing (1996)

Vendor selection is an important problem in today's competitive environment . Decisions involve the selection of vendors and the determination of order quantities to be placed with the selected vendors. In this research we develop a mathematical programming model for this purpose using an Activity Based Costing approach. The system computes the total cost of ownership, thereby increasing the objectivity in the selection process and giving the opportunity for different kinds of sensitivity analysis. Moreover, it allow the analyst to objectively evaluate alternative purchasing policies due to the underlying analytic and rigorous decision model.
<scp>l</scp>-THYROXINE AND 3,5,3’-TRII000-<scp>l</scp>-THYRONINE IN RAT EMBRYOS BEFORE ONSET OF FETAL THYROID FUNCTION. (1984)

T4 and T3 have been measured by RIA in 10-12-day-old rat embryo-trophoblasts, and in 13-20-day-old embryos and placentas, as well as in a few samples of amniotic fluid. Both T4 and T3 were measured after extraction of the samples with ethanol, purification by paper chromatography, anion exchange resin, or both. T4 and T3 could be shown in all samples studied. The amounts of T4 and T3 per conceptus and their concentrations were higher in embryo-trophoblasts and placentas than in 13-18-day-old embryos. The concentrations of T4 and T3 remained fairly constant in the embryos until day 19, when they appeared to increase. The molar ratios of T4 to T3 were 1.4, 8.5 and 103 for embryos, placentas and maternal plasma, respectively. These data show that, for at least one mammalian species, embryonic tissues are provided with T4 and T3 from the earliest date studied, namely 4 days after uterine implantation, and well before onset of thyroid function, which in the rat starts after 17 days gestational age. Such a result suggests that statements denying a possible role of thyroid hormones in early embryogenesis ought to be reconsidered.
Copper binding to the Alzheimer’s disease amyloid precursor protein (2007)

Alzheimer's disease is the fourth biggest killer in developed countries. Amyloid precursor protein (APP) plays a central role in the development of the disease, through the generation of a peptide called A beta by proteolysis of the precursor protein. APP can function as a metalloprotein and modulate copper transport via its extracellular copper binding domain (CuBD). Copper binding to this domain has been shown to reduce A beta levels and hence a molecular understanding of the interaction between metal and protein could lead to the development of novel therapeutics to treat the disease. We have recently determined the three-dimensional structures of apo and copper bound forms of CuBD. The structures provide a mechanism by which CuBD could readily transfer copper ions to other proteins. Importantly, the lack of significant conformational changes to CuBD on copper binding suggests a model in which copper binding affects the dimerisation state of APP leading to reduction in A beta production. We thus predict that disruption of APP dimers may be a novel therapeutic approach to treat Alzheimer's disease.
Sensor nanofabrication, performance, and conduction mechanisms in scanning thermal microscopy (1997)

A new nanofabrication procedure has been developed for making thermocouple probes for high-resolution scanning thermal microscopy. Thermocouple junctions were placed at the end of SiNx cantilever probe tips and were typically 100–500 nm in diameter. Cantilever bending due to thermal expansion mismatch was minimized for Au–Ni, Au–Pt, and Au–Pd thermocouples, by carefully choosing thermal probe materials, film thicknesses, and deposition conditions. A spatial resolution of 24 nm was demonstrated for thermal microscopy although the noise-equivalent limit of 10 nm was estimated from experimental data. Using thermo-power measurements, a simple model was developed to calculate the tip-sample thermal resistance. Model-based calculations, correlations between topographical and thermal features, as well as experiments in different gaseous and humidity environments indicate that the dominant tip-surface heat conduction is most likely through a liquid film bridging the tip and the sample surface, and not through the surrounding gas, solid-solid point contact, or near-field radiation. Dynamic measurements within a 100 kHz bandwidth showed a time constant of about 0.15±0.02 ms which was attributed to the thermal time constant of the whole cantilever. Calculations suggested the RC electrical time constant and the thermal time constant of the thermocouple junction to be on the order of 10 ns which, however, could not be experimentally probed.
Radioactive <sup>125</sup>I seed implantation for locally advanced pancreatic cancer: A retrospective analysis of 50 cases (2020)

Radioactive <sup>125</sup>I seed implantation combined with postoperative chemotherapy can prolong the survival time, relieve pain, and improve the quality of life of patients with locally advanced pancreatic cancer.
Glass Formation in the System SiO <sub>2</sub> –PbO Containing Transition‐Metal Oxides (1989)

Glass‐forming regions, valence states, and viscosities in SiO 2 –PbO systems containing various transition‐metal oxides as a third component were investigated. The glasses were prepared by melting in an open atmosphere. The glass‐forming regions ranged as follows: MnO≡ZnO > FeO 1.5 >NiO. The ratios Fe 2+ /(Fe 2+ + Fe 3+ ) and Mn 3+ / (Mn 3+ + Mn 2+ ) in the glasses were determined by chemical analysis. The Fe 2+ / (Fe 2+ + Fe 3+ ) ratio in SiO 2 –PbO–FeO 1.5 glasses ranged from 0.016 to 0.050. The Mn 3+ / (Mn 3+ + Mn 2+ ) ratio in SiO 2 –PbO–MnO glasses ranged from 0.056 to 0.30. The fraction of manganese (III) ions in the glasses varies considerably with the glass composition. The effects of transitionmetal oxides on the viscosity are discussed.
Antisemitismo, antijudaísmo y xenofobia: conceptos y contextos en la Antigüedad y la Alta Edad Media (2016)

Fil: Laham Cohen, Rodrigo Jaime. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Saavedra 15. Instituto Multidisciplinario de Historia y Ciencias Humanas; Argentina
Encoding and decoding nanoscale thermal barcodes for ultrahigh capacity identification systems (2009)

An ultrahigh capacity coding system is created based on the solid to liquid phase changes of a variety of nanoparticles, which are designed and prepared with sharp, discrete melting peaks and encapsulated inside nonmelting shells. A mixture of such thermally-active nanoparticles at designed ratio can be embedded inside an object as a nanoscale barcode that can be decoded by differential thermal scan. The coding capacity depends on the number of melting peaks, which in turn depends on nanoparticle compositions. A coding system with 50 different compositions can generate over 1015 thermal barcodes, sufficient for many identification applications.
Reversal of stereochemical path in allylic alkylations promoted by palladium and molybdenum complexes (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReversal of stereochemical path in allylic alkylations promoted by palladium and molybdenum complexesJack W. Faller and Douglas LinebarrierCite this: Organometallics 1988, 7, 7, 1670–1672Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://pubs.acs.org/doi/10.1021/om00097a040https://doi.org/10.1021/om00097a040research-articleACS PublicationsRequest reuse permissionsArticle Views237Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Intakes of vitamins E and C, carotenoids, vitamin supplements, and PD risk (2002)

Use of vitamin supplements and high intake of carotenoids do not appear to reduce the risk of PD. The reduction in risk of PD associated with high dietary vitamin E intake suggests that other constituents of foods rich in vitamin E may be protective. Alternatively, moderate amounts of vitamin E may reduce risk of PD, but this benefit may be lost with higher intakes.
High Responsivity, Low Dark Current Ultraviolet Photodetectors Based on Two-Dimensional Electron Gas Interdigitated Transducers (2018)

An ultraviolet (UV) photodetector employing the two-dimensional electron gas (2DEG) formed at the AlGaN/GaN interface as an interdigitated transducer (IDT) is characterized under optical stimulus. The 2DEG-IDT photodetector exhibits a record high normalized photocurrent-to-dark current ratio of 6 × 1014. We also observe a high responsivity (7800 A/W) and ultraviolet–visible rejection ratio (106), among the highest reported values for any GaN photodetector architecture. We argue that the valence band offset in the AlGaN/GaN heterostructure is essential in achieving this high responsivity, allowing for large gains without necessitating the presence of trap states. Our proposed gain mechanism is consistent with measurements of the scaling of gain with device channel width and incident power. The photodetector architecture has a simple two-step fabrication process, compatible with AlGaN/GaN high electron mobility transistor (HEMT) processing. This unique combination of low dark current, high responsivity, and simple fabrication is attractive for a variety of UV sensing applications.
Unexpected Sensitivity of sst<sub>2</sub> Antagonists to N-Terminal Radiometal Modifications (2012)

Chelated somatostatin agonists have been shown to be sensitive to N-terminal radiometal modifications, with Ga-DOTA agonists having significantly higher binding affinity than their Lu-, In-, and Y-DOTA correlates. Recently, somatostatin antagonists have been successfully developed as alternative tracers to agonists. The aim of this study was to evaluate whether chelated somatostatin antagonists are also sensitive to radiometal modifications and how. We have synthesized 3 different somatostatin antagonists, DOTA-p-NO(2)-Phe-c[D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys]-D-Tyr-NH(2), DOTA-Cpa-c[D-Cys-Aph(Hor)-D-Aph(Cbm)-Lys-Thr-Cys]-D-Tyr-NH(2) (DOTA-JR11), and DOTA-p-Cl-Phe-c[D-Cys-Tyr-D-Aph(Cbm)-Lys-Thr-Cys]-D-Tyr-NH(2), and added various radiometals including In(III), Y(III), Lu(III), Cu(II), and Ga(III). We also replaced DOTA with 1,4,7-triazacyclononane,1-glutaric acid-4,7-acetic acid (NODAGA) and added Ga(III). The binding affinity of somatostatin receptors 1 through 5 was evaluated in all cases. In all 3 resulting antagonists, the Ga-DOTA analogs were the lowest-affinity radioligands, with a somatostatin receptor 2 binding affinity up to 60 times lower than the respective Y-DOTA, Lu-DOTA, or In-DOTA compounds. Interestingly, however, substitution of DOTA by the NODAGA chelator was able to increase massively its binding affinity in contrast to the Ga-DOTA analog. The 3 NODAGA analogs are antagonists in functional tests. In vivo biodistribution studies comparing (68)Ga-DOTATATE agonist with (68)Ga-DOTA-JR11 and (68)Ga-NODAGA-JR11 showed not only that the JR11 antagonist radioligands were superior to the agonist ligands but also that (68)Ga-NODAGA-JR11 was the tracer of choice and preferable to (68)Ga-DOTA-JR11 in transplantable HEK293-hsst(2) tumors in mice. One may therefore generalize that somatostatin receptor 2 antagonists are sensitive to radiometal modifications and may preferably be coupled with a (68)Ga-NODAGA chelator-radiometal complex.
A flexible architecture for pointcut-advice language implementations (2007)

Current implementations for aspect-oriented programming languages map the aspect-oriented concepts of source programs to object-oriented bytecode. This hinders execution environments with dedicated support for such concepts in applying their optimizations, as they have to recover the original aspect definition from bytecode. To address this representational gap we propose an architecture for implementations of pointcut-advice languages where aspect-oriented concepts are preserved as first-class entities. In this architecture, compilers generate a model of the crosscutting which is executed by virtual machines.
Treatment of Vitamin B<sub>12</sub>–Deficiency Anemia: Oral versus Parenteral Therapy (2002)

Daily oral cyanocobalamin at doses of 1000-2000 microg can be used for treatment in most cobalamin-deficient patients who can tolerate oral supplementation. There are inadequate data at the present time to support the use of oral cyanocobalamin replacement in patients with severe neurologic involvement.
Role of an endoplasmic reticulum Ca<sup>2+</sup>-independent phospholipase A<sub>2</sub>in oxidant-induced renal cell death (2002)

Phospholipase A(2) (PLA(2)) hydrolyzes the sn-2 ester bond in phospholipids, releasing a fatty acid and a lysophospholipid. Recently, a novel 85-kDa membrane-bound-Ca(2+)-independent PLA(2) (iPLA(2)) was identified in insect and bacterial cells transfected with candidate PLA(2) sequences. However, few data exist demonstrating a membrane-bound-iPLA(2) in mammalian cells, its subcellular localization, or its physiological role. Herein, we demonstrate the expression of an 85-kDa endoplasmic reticulum (ER)-Ca(2+)-iPLA(2) (ER-iPLA(2)) in rabbit renal proximal tubule cells (RPTC) that is plasmalogen selective and is inhibited by the specific Ca(2+)-iPLA(2) inhibitor bromoenol lactone (BEL). RPTC exposed to tert-butylhydroperoxide for 24 h exhibited 20% oncosis compared with 2% in controls. Inhibition of ER-iPLA(2) with BEL before tert-butylhydroperoxide exposure resulted in 50% oncosis. To determine whether this effect was common to oxidants, we tested the ability of BEL to potentiate oncosis induced by cumene hydroperoxide, menadione, duraquinone, cisplatin, and the nonoxidant antimycin A. All oxidants tested produced oncosis after 24 h, and prior inhibition of ER-iPLA(2) potentiated oncosis at least twofold. In contrast, inhibition of ER-iPLA(2) did not alter antimycin A-induced oncosis. Lipid peroxidation increased from 1.4- to 5.2-fold in RPTC treated with BEL before oxidant exposure, whereas no change was seen in antimycin A-treated RPTC. These results are the first to demonstrate the expression and subcellular localization of an ER-iPLA(2). These results also suggest that ER-iPLA(2) functions to protect against oxidant-induced lipid peroxidation and oncosis.
Color standardization in whole slide imaging using a color calibration slide (2014)

Color variations in histological images brought about by whole slide scanning can be effectively normalized with the use of the color calibration slide.
Semiconductor quantum light emitters and sensors (2010)

Quantum light emitters have great application potential in quantum key distribution, precision metrology and quantum imaging. We present triggered electrically driven single photon sources based on semiconductor quantum dots in GaAs/AlAs micropillar cavities with on demand single photon rates of 35 MHz while a record outcoupling efficiency up to 34 % is obtained. Photon autocorrelation measurements reveal g<sup>(2)</sup>(0) down to 0.13. The high efficiency is achieved due to an optimized contact scheme which allows for the injection of electrical current into micropillar cavities which are characterized by low absorption losses and diameters down to 1 μm. By exploiting the established fabrication procedure, micropillar cavities exhibiting pronounced cavity quantum electrodynamics effects have been realized. Furthermore, by applying a reverse bias to the micropillar cavities, photocurrent measurements allow for wavelength selective sensing of light at powers down to 20 nW and further design changes promise photon detection sensitivities approaching the quantum limit.
Medical image segmentation by improved 3D adaptive thresholding (2015)

To see CT and MRI medical images of slice type easily, or to print using 3D printer, we should make a 3D model from slice images. In this paper, we suggest the Improved Adaptive Segmentation Algorithm which can perform the segmentation process which is the most important process at making 3D model. The adaptive threshold method can detect object boundary effectively in an image luminance bias, but tends to diverge at flat region. The proposed algorithm checks the bimodality at histogram distribution and makes adaptive threshold algorithm works stably.
ARIES (ARtificial Intelligence for Ecosystem Services ): a new tool for ecosystem services assessment, planning, and valuation. (2009)

ARIES is a new methodology and web application meant to assess ecosystem services (ES) and illuminate their values to humans in order to make environmental decisions easier and more effective. By creating ad-hoc, probabilistic models of both provision and usage of ES in a region of interest, and mapping the actual physical flows of those benefits to their beneficiaries, ARIES helps discover, understand, and quantify environmental assets, and what factors influence their value according to explicit needs and priorities. In this contribution, we present the basic elements of the ARIES methodology and illustrate perspectives for integration of new ES thinking into science, decisionand policy-making.