gebhart/patrepeval huggingface dataset:
Specificity of pyoverdine-mediated iron uptake among fluorescent Pseudomonas strains (1988)

Pyoverdine-mediated iron transport was determined for seven fluorescent Pseudomonas strains belonging to different species. For all strains, cell or cell outer membrane and iron(III)-pyoverdine combinations were compared with their homologous counterparts in uptake, binding, and cross-feeding experiments. For four strains (Pseudomonas putida ATCC 12633, Pseudomonas fluorescens W, P. fluorescens ATCC 17400, and Pseudomonas tolaasii NCPPB 2192), the pyoverdine-mediated iron transport appeared to be strictly strain specific; pyoverdine-facilitated iron uptake by iron-starved cells and binding of ferripyoverdine to the purified outer membranes of such cells were efficient only in the case of the homologous systems. Cross-feeding assays, in liquid or solid cultures, resulted, however, especially for P. fluorescens ATCC 17400, in some discrepancies compared with uptake and binding assays, suggesting that growth experiments are the least likely to yield correct information on specificity of the pyoverdine-mediated iron transport. For the three other strains (P. fluorescens ATCC 13525, P. chlororaphis ATCC 9446, and P. aeruginosa ATCC 15692), cross-reactivity was demonstrated by the uptake, binding, and cross-feeding experiments. In an attempt to determine which parts of the iron transport system were responsible for the specificity, the differences in amino acid composition of the pyoverdines, together with the differences observed at the level of the iron-sensitive outer membrane protein pattern of the seven strains, are discussed.
SAT-based approaches to verification of logical descriptions with functional indeterminacy (2013)

The problem under discussion is to check whether a given system of incompletely specified Boolean functions is implemented by a logical description that is represented by a system of connected blocks each of which is specified by a system of completely or incompletely specified Boolean functions. SAT-based verification approaches are considered which formulate the verification problem as checking satisfiability of a conjunctive normal form. The results of investigation of SAT-based verification methods are given.
The mammalian homologue of the novel peptide Bv8 is expressed in the central nervous system and supports neuronal survival by activating the MAP kinase/PI‐3‐kinase pathways (2001)

Previous studies have identified the mammalian homologue of Bv8 (mBv8), a small protein originally isolated from skin secretions of the frog, Bombina variegata. In situ hybridization showed that mBv8 RNA was widely expressed in the rodent CNS, with high levels being detected in layer II of the cerebral cortex, limbic regions, cerebellar Purkinje cells, and dorsal and ventral horns of the spinal cord. A similar pattern of distribution was found by examining the presence of mBv8 protein by immunocytochemistry. Addition of frog Bv8 to cultured cerebellar granule cells reduced the extent of apoptotic death induced by switching the growing medium from 25 to 5 mM K+. Bv8 could also protect cultured cortical neurons against excitotoxic death. Both effects were prevented by PD98059 and LY294002, which inhibit the mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI-3-K) pathways, respectively. In cultured cerebellar granule cells, Bv8 stimulated both the MAPK and the PI-3-K pathways, as revealed by Western blot analysis of phosphorylated p44/p42 MAPKs and phosphorylated Akt, respectively. We conclude that mBv8 acts as an endogenous neurotrophic factor and supports neuronal survival through the activation of the MAPK/PI-3-K pathways.
Sensitization of Human Pancreatic Cancer Cells Harboring Mutated K-ras to Apoptosis (2012)

Pancreatic cancer is a devastating human malignancy and gain of functional mutations in K-ras oncogene is observed in 75%-90% of the patients. Studies have shown that oncogenic ras is not only able to promote cell growth or survival, but also apoptosis, depending upon circumstances. Using pancreatic cancer cell lines with or without expressing mutated K-ras, we demonstrated that the inhibition of endogenous PKC activity sensitized human pancreatic cancer cells (MIA and PANC-1) expressing mutated K-ras to apoptosis, which had no apoptotic effect on BxPC-3 pancreatic cancer cells that contain a normal Ras as well as human lung epithelial BAES-2B cells. In this apoptotic process, the level of ROS was increased and PUMA was upregulated in a p73-dependent fashion in MIA and PANC-1 cells. Subsequently, caspase-3 was cleaved. A full induction of apoptosis required the activation of both ROS- and p73-mediated pathways. The data suggest that PKC is a crucial factor that copes with aberrant K-ras to maintain the homeostasis of the pancreatic cancer cells harboring mutated K-ras. However, the suppression or loss of PKC disrupts the balance and initiates an apoptotic crisis, in which ROS and p73 appear the potential, key targets.
Nanometer Resolution and Coherent Optical Dipole Coupling of Two Individual Molecules (2002)

By performing cryogenic laser spectroscopy under a scanning probe electrode that induces a local electric field, we have resolved two individual fluorescent molecules separated by 12 nanometers in an organic crystal. The two molecules undergo a strong coherent dipole-dipole coupling that produces entangled sub- and superradiant states. Under intense laser illumination, both molecules are excited via a two-photon transition, and the fluorescence from this doubly excited system displays photon bunching. Our experimental scheme can be used to optically resolve molecules at the nanometer scale and to manipulate the degree of entanglement among them.
Synthesis of Inorganic Solids Using Microwaves (1999)

Use of microwaves in the synthesis of materials is gaining importance. Microwave-assisted synthesis is generally much faster, cleaner, and more economical than the conventional methods. A variety of materials such as carbides, nitrides, complex oxides, silicides, zeolites, apatite, etc. have been synthesized using microwaves. Many of these are of industrial and technological importance. An understanding of the microwave interaction with materials has been based on concepts of dielectric heating and of the resonance absorption due to rotational excitation. This review presents a summary of recent reports of microwave synthesis of inorganic materials. Various observations regarding microwave interaction with materials are also briefly discussed.
On the Growth of CdS Nanowires by the Evaporation of CdS Nanopowders (2002)

This article describes for the first time the direct observation of the nucleation and growth process of CdS nanowires in a typical vapor−solid synthetic route. Thermal evaporating of CdS nanosized powders at 1173 K for various time durations corresponds to different growth stages and leads to varied product morphologies. Initially, CdS appeared as amorphous spherical particles, followed by nucleation of nanorods from cusps on the particle surface. Subsequently, nanorods developed to nanowires with matrix particles being consumed. Strategies could be optimized to grow CdS nanowires of varied diameters and lengths for a variety of applications.
Enhanced Oxidative Stress in iNOS-Deficient Mice after Traumatic Brain Injury: Support for a Neuroprotective Role of iNOS (2005)

Studies in experimental traumatic brain injury (TBI) suggest both deleterious and protective effects of inducible nitric oxide synthase (iNOS). Early after injury, iNOS may be detrimental via formation of peroxynitrite and iNOS inhibitors are protective. In contrast, we reported impaired long-term functional outcome after TBI in iNOS knockout (ko) versus wild-type (wt) mice. To elucidate potential neuroprotective and neurotoxic mechanisms for iNOS, we studied nitric oxide formation by electron paramagnetic resonance (EPR) spectroscopy using diethyldithiocarbamate-iron (DETC-Fe) as a spin trap and markers of nitrosative (S-nitrosothiol (RSNO, Fluorescent assay); nitrotyrosine (3NT, ELISA)) and oxidative stress (ascorbate, HPLC) at 72 h after controlled cortical impact (CCI) in iNOS ko and wt and in uninjured iNOS ko and wt mice. 3NT immunostaining with macrophage and myeloperoxidase (MPO) dual labeling was also assessed in brain sections. Brain DETC-Fe-NO low-temperature EPR signal intensity was approximately 2-fold greater in wt versus iNOS ko at 72 h after CCI. Ascorbate levels decreased in injured hemisphere in wt and iNOS ko versus uninjured -this decrease was more pronounced in iNOS ko. In wt mice, RSNO and 3NT levels were increased after CCI versus uninjured (50% and 400%, respectively, P < 0.05). RSNO levels were not increased in iNOS ko after CCI. Nitrotyrosine levels increased after CCI in wt and ko versus respective uninjured -this increase was more pronounced in wt (2.34 +/- 0.95 versus 1.27 +/- 0.49 pmol/mg protein, P < 0.05). Increased 3NT immunoreactivity was detected in wt versus iNOS ko at 72 h after CCI, and colocalized with macrophage marker and MPO. Our data support a role for iNOS-derived NO as an endogenous antioxidant after CCI. iNOS also contributes protein nitrosylation and nitration. Colocalization of 3NT with macrophages and MPO suggests generation of nitrating agents by macrophages and/or phagocytosis of nitrated proteins.
Single incision technique for implantation of subcutaneous implantable cardioverter defibrillators (2018)

A single incision for subcutaneous ICDs is feasible and safe in our early experience.
Cyanopeptolin 954, a Chlorine-Containing Chymotrypsin Inhibitor of <i>Microcystis </i><i>a</i><i>eruginosa</i> NIVA Cya 43 (2005)

A new depsipeptide, cyanopeptolin 954 (1), was isolated from the freshwater cyanobacterium Microcystis aeruginosa NIVA Cya 43. The structure of the compound was elucidated by chemical and spectroscopic analyses, including 2D NMR and GC-MS of the hydrolysate. The major structural differences compared to previously characterized heptadepsipeptides of Microcystis are the replacement of the basic amino acid in position 4 by L-leucine, the presence of L-phenylalanine in position 6, and the uncommon residue 3'-chloro-N-Me-L-tyrosine in position 7. Cyanopeptolin 954 inhibited chymotrypsin with an IC50 value of 45 nM. Nostopeptin BN920, formerly isolated from the cyanobacterium Nostoc,(1) was isolated from the same strain of Microcystis, and a cis amide bond between Phe (6) and N-Me-Tyr (7) was shown. Nostopeptin BN920 inhibited chymotrypsin with an IC50 value of 31 nM.
Ultrafast Electron, Lattice and Spin Dynamics on Rare-Earth Metal Surfaces (2006)

This thesis presents the femtosecond laser-induced electron, lattice and spin dynamics on two representative rare-earth systems: The ferromagnetic gadolinium Gd(0001) and the paramagnetic yttrium Y(0001) metals. The employed investigation tools are the time-resolved linear reflectivity and second- harmonic generation, which provide complementary information about the bulk and surface/interface dynamics, respectively. The femtosecond laser excitation of the exchange-split surface state of Gd(0001) triggers simultaneously the coherent vibrational dynamics of the lattice and spin subsystems in the surface region at a frequency of 3 THz. The coherent optical phonon corresponds to the vibration of the topmost atomic layer against the underlying bulk along the normal direction to the surface. The coupling mechanism between phonons and magnons is attributed to the modulation of the exchange interaction J between neighbour atoms due to the coherent lattice vibration. This leads to an oscillatory motion of the magnetic moments having the same frequency as the lattice vibration. Thus these results reveal a new type of phonon-magnon coupling mediated by the modulation of the exchange interaction and not by the conventional spin-orbit interaction. Moreover, we show that coherent spin dynamics in the THz frequency domain is achievable, which is at least one order of magnitude faster than previously reported. The laser-induced (de)magnetization dynamics of the ferromagnetic Gd(0001) thin films have been studied. Upon photo-excitation, the nonlinear magneto-optics measurements performed in this work show a sudden drop in the spin polarization of the surface state by more than 50% in a <100 fs time interval. Under comparable experimental conditions, the time-resolved photoemission studies reveal a constant exchange splitting of the surface state. The ultrafast decrease of spin polarization can be explained by the quasi-elastic spin-flip scattering of the hot electrons among spin-mixed states. The angular momentum conservation is fulfilled by emission or absorption of magnons, that can involve also the 4f moments. On epitaxially grown Y(0001)/W(110) thin films the femtosecond laser excitation launches acoustic phonons wavepackets at GHz frequencies, which travel back and forth within the Y(0001) film (the so called phonon echo). Their signature is reflected in the transient linear reflectivity signal as sharp peaks with alternating polarity that appear at regular time intervals. From these data, accurate values for the film thickness, sound velocity and optical penetration depth as well as the photoelastic constants of yttrium could be retrieved.
Batch fabrication and structure of integrated GaAs-Al/sub x/Ga/sub 1-x/As field-effect transistor-self-electro-optic effect devices (FET-SEED's) (1992)

The authors have demonstrated a smart pixel prototype field-effect-transistor-self-electrooptic-effect-device (FET-SEED) integrated optoelectronic amplifier utilizing process technology suitable for flexible design and fabrication of high-yield optoelectronic circuits. A single MBE growth sequence provides for quantum-well modulators, photodiodes, doped channel MIS-like field-effect transistors (DMTs), and resistors. The device dimensions are controlled in a planar technology using ion implantation and selective plasma etching for isolation and contacting. Results demonstrate optical amplification in a fully integrated circuit. This technology will enable increased functionality by providing digital electronic processing between optical input and output.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Performance of a 32 kbit/s ADPCM coder for digital long-haul telephone transmission (2005)

A 32 kbit/s rate per channel would double the capacity of digital links compared with 62 kbit/s standard PCM and permit digital techniques to be used throughout in telecommunication networks. The requirements imposed on a coding scheme for long-haul telephone transmission are reviewed. Besides the minimal complexity of implementation, the toll-quality level, the capability of handling signals other than speech, a crucial feature is the non cumulation of degradations in successive coding-decoding processes. An ADPCM coder is proposed ; in the implementation with finite precision arithmetic, both adapted quantization step sizes and prediction filter outputs track in coder and decoder. Experimental results show that the 32 kbit/s scheme outperforms 56 kbit/s PCM for speech in several aspects and is adequate for data transmission up to 4800 bit/s.
NADPH Oxidase 1-Mediated Oxidative Stress Leads to Dopamine Neuron Death in Parkinson's Disease (2011)

We provide evidence that dopaminergic neurons are equipped with the Nox1/Rac1 superoxide-generating system. Stress-induced Nox1/Rac1 activation causes oxidative DNA damage and neurodegeneration. Reduced dopaminergic neuronal death achieved by targeting Nox1/Rac1, emphasizes the impact of oxidative stress caused by this system on the pathogenesis and therapy in Parkinson's disease.
Beyond RPC: the Virtual Network (1993)

Although RPC is the current method of choice for distributed interprocess communication, its complexity might increase demand for higher-level approaches. The Virtual Network, an idealized, intelligent software network that hides the underlying physical network's incompatibilities and complexities from the distributed programs that run on it, is presented as a solution. The components of the Virtual Network are described, and meta communication, error handling, system administration, performance, and security issues are discussed. The Virtual Network is compared with DCE RPC, the de facto standard. The use of the Virtual Network framework to quickly design and implement a useful, sophisticated distributed application, the distributed Ada compilation tool, is described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Technique to Estimate the Approximate Size of Photographed Bats (2006)

Bats (Order Chiroptera) often are photographed by automatic cameras with infrared sensors set in forests for wildlife surveys. To facilitate species identification of the photographed bats, we have developed a technique to estimate their approximate size using their shadows. This technique gives unbiased size estimates, but its precision depends on the accuracy of parameters used (camera-position parameters and on-film measurements). Used with due care, this technique could be a useful tool to identify some species of automatically photographed bats. Because this technique is in spreadsheet format, the estimates and their confidence limits are obtained simply by filling in the required parameter values and their possible level of errors.
A byte-erasure method for improved impulse immunity in DSL systems using soft information from an inner code (2004)

A significant portion of the end-to-end delay in high-rate DSL systems is due to the impulse noise protection scheme employed in order to shield those systems against random, non-stationary noise bursts of high energy that appear on the copper lines. Systems are protected from impulse noise using a combination of interleaving and Reed-Solomon codes. In order to lower the end-to-end delay without reducing the data rate that is available to the user, one needs to decrease the interleaver depth. This paper presents a way to achieve this reduction without compromising neither the robustness to noise bursts nor the data rate of the system. The proposed algorithm relies on the inner code used by many DSL systems and uses the metric provided by the inner code decoder at the receiver. A DMT-VDSL system is used as a particular example of the achieved reduction of the end-to-end delay.
Preservation of grain with aliphatic 1,3-diols and their esters (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreservation of grain with aliphatic 1,3-diols and their estersJohn W. Frankenfeld, Raam R. Mohan, and Robert L. SquibbCite this: J. Agric. Food Chem. 1975, 23, 3, 418–425Publication Date (Print):May 1, 1975Publication History Published online1 May 2002Published inissue 1 May 1975https://pubs.acs.org/doi/10.1021/jf60199a046https://doi.org/10.1021/jf60199a046research-articleACS PublicationsRequest reuse permissionsArticle Views89Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
New Approach to Improve the Horizontal Drilling Reach (2010)

Abstract In order to improve the cost efficiency of petroleum exploration and production, it is required to develop improved technology. The Reelwell Drilling Method (RDM) is a multi purpose drilling method with a unique arrangement for Extended Reach Drilling and Managed Pressure Drilling. A conventional drill string with a special inner string forms a dual concentric drill string, which is used to remove drill cuttings from the bottom of the well. A separate hydraulic fluid system is used to push the drilling assembly forward using fluid pressure from the surface. The development of RDM started in 2004 and has since then been through several full scale operations in Norway. In 2009 RDM was successfully used to directional drill the 8 ½" section of a land well. The proof of concept and the practical application on conventional drilling rigs has been verified, as well as the features of the system, such as: - Managed Pressure Drilling (MPD) – Unique isolation using a new downhole valve solution. - Very precise well pressure management and flow control (gain/loss). - Efficient hole cleaning and cutting removal from wellbore - Efficient hydraulic traction and WOB control. The RDM is currently planned to be used for drilling horizontal wells in Canada. The potential to increase the reach for horizontal wells is here further discussed.
Interventions for emergency contraception (2008)

Mifepristone middle dose (25-50 mg) was superior to other hormonal regimens. Mifepristone low dose (<25 mg) could be more effective than levonorgestrel 0.75 mg (two doses) but this was not conclusive. Levonorgestrel proved more effective than the Yuzpe regimen. The copper IUD was another effective emergency contraceptive that can provide ongoing contraception.
Aerosol Jet Printed, Low Voltage, Electrolyte Gated Carbon Nanotube Ring Oscillators with Sub-5 μs Stage Delays (2013)

A central challenge for printed electronics is to achieve high operating frequencies (short transistor switching times) at low supply biases compatible with thin film batteries. In this report, we demonstrate partially printed five-stage ring oscillators with >20 kHz operating frequencies and stage delays <5 μs at supply voltages below 3 V. The fastest ring oscillator achieved 1.2 μs delay time at 2 V supply. The inverter stages in these ring oscillators were based on ambipolar thin film transistors (TFTs) employing semiconducting, single-walled carbon nanotube (CNT) networks and a high capacitance (∼1 μF/cm(2)) ion gel electrolyte as the gate dielectric. All materials except the source and drain electrodes were aerosol jet printed. The TFTs exhibited high electron and hole mobilities (∼20 cm(2)/(V s)) and ON/OFF current ratios (up to 10(5)). Inverter switching times t were systematically characterized as a function of transistor channel length and ionic conductivity of the gel dielectric, demonstrating that both the semiconductor and the ion gel play a role in switching speed. Quantitative scaling analysis suggests that with suitable optimization low voltage, printed ion gel gated CNT inverters could operate at frequencies on the order of 1 MHz.
Camera calibration and performance evaluation of depth from defocus (DFD) (2005)

Real-time and accurate autofocusing of stationary and moving objects is an important problem in modern digital cameras. Depth From Defocus (DFD) is a technique for autofocusing that needs only two or three images recorded with different camera parameters. In practice, there exist many factors that affect the performance of DFD algorithms, such as <i>nonlinear sensor response, lens vignetting, and magnification variation</i>. In this paper, we present calibration methods and algorithms for these three factors. Their correctness and effects on the performance of DFD have been investigated with experiments.