gebhart/patrepeval huggingface dataset:
Amorphous wire MI micro sensor using C-MOS IC multivibrator (1997)

A family of sensitive, stable and low power consumption MI micro magnetic sensors are constructed using a CMOS IC multivibrator circuit, in which a sharp pulse train current is applied to an amorphous wire to cause the skin effect. A micro field sensor having a resolution of 10/sup -6/ Oe with a full scale (FS) of /spl plusmn/1.5 Oe and a nonlinearity of less than 0.2%, a cut-off frequency of /spl sim/200 kHz, and a power consumption in the oscillation circuit of 0.5/spl sim/5 mW is obtained using a zero-magnetostrictive FeCoSiB amorphous wire of 30 /spl mu/m diameter and 2 mm length. A differential field sensor is also constructed using a pair of amorphous wires suitable for detection of a localized held with the resolution of 10/sup -4/ Oe cancelling uniform disturbance fields such as terrestrial field. Non-contact sensing of a magnetic card surface field was demonstrated.
A Randomized Clinical Trial on Preventing Pressure Ulcers with Wheelchair Seat Cushions (2010)

Skin protection cushions used with fitted wheelchairs lower pressure ulcer incidence for elderly nursing home residents and should be used to help prevent pressure ulcers.
P‐16: Solution‐Processed Zinc Oxide Thin‐Film Transistors (2007)

Abstract Methods for producing zinc oxide thin‐film transistors by solution processing were studied. One class of methods involves the use of zinc‐acetate‐based precursor solutions, while the other involves the use of preformed nanoparticles. Devices with reasonable transfer characteristics were obtained from both routes, exhibiting mobilities typically greater than 0.1 cm 2 /Vs.
Journal of Bone and Mineral Research (1992)

The use of hydrostatic pressure to apply mechanical stress to bone organ cultures is reviewed. Ossifying long bones and calvarial rudiments are sensitive to this type of stress. Intermittent hydrostatic compression of near physiologic magnitude (ICF) has anabolic effects on mineral metabolism in such rudiments, and continuous hydrostatic stress of high magnitude (CCP) has catabolic effects. The effects of ICF may be ascribed to shear stress generated at tissue interphases of different chemical and mechanical properties. Local factors, such as prostaglandins and growth factors, seem to be involved in the tissue response to mechanical stress.
Recombination analysis reveals a double recombination event in hepatitis E virus (2010)

Recombination of Hepatitis E Virus (HEV) has rarely been reported. In the present study, phylogenetic and recombination analyses were performed on 134 complete HEV genomes. Three potentially significant recombination events, including both intra-genotype and one inter-genotype, were identified by recombination detection analysis. Recombination events I and II occurred intra-genotype and inter-genotype, respectively, among three isolates, including the lineage represented by CHN-XJ-SW13 (GU119961, swine isolate), E067-SIJ05C (AB369690, human isolate), and JJT-Kan (AB091394, human isolate), and lead to the recombinant swine isolate swCH31 (DQ450072). Recombination event III occurred between the lineage represented by the NA1 (M73218) and K52-87 (L25595), which resulted in the recombinant Xingjiang-1 (D11092). Our analyses proved that that recombination could occur between human and swine HEV strains, double recombination events existed in HEV, and recombination event could happen within ORF2 region of HEV. These results will provide valuable hints for future research on HEV diversity.
Faster electro-optical response characteristics of a carbon-nanotube-nematic suspension (2007)

The response times of rotational molecular orientation of neat and carbon-nanotube-doped nematic liquid crystals were acquired through the measurement of transient current induced by a direct-current step voltage and from optical transmission data. A model based on the dielectric displacement current was developed to describe the electric field dependence of the response and to yield a rotational viscosity that would decrease with increasing concentration of carbon nanotubes. Optical dynamic response also showed a reduced rotational viscosity, with the lightly doped cells exhibiting a faster relaxation process than that of the neat cell.
Design and Characterization of Helical Peptides that Inhibit the E6 Protein of Papillomavirus<sup>,</sup> (2004)

The E6 protein from HPV type 16 binds proteins containing a seven-residue leucine-containing motif. Previous work demonstrated that peptides containing the consensus sequence are a mixture of α-helix and unstructured conformations. To design monomeric E6-binding peptides that are stable in aqueous solution, we used a protein grafting approach where the critical residues of the E6-binding motif of E6-associated protein, E6AP, LQELLGE, were incorporated into exposed helices of two stably folded peptide scaffolds. One series was built using the third zinc finger of the Sp1 protein, which contains a C-terminal helix. A second series was built using a Trp-cage scaffold, which contains an N-terminal helix. The chimeric peptides had very different activities in out-competing the E6−E6AP interaction. We characterized the peptides by circular dichroism spectroscopy and determined high-resolution structures by NMR methods. The E6-binding consensus motif was found to be helical in the high-quality structures, which had backbone root-mean-square deviations of less than 0.4 Å. We have successfully grafted the E6-binding motif into two parent peptides to create ligands that have biological activity while preserving the stable, native fold of their scaffolds. The data also indicate that conformational change is common in E6-binding proteins during the formation of the complex with the viral E6 protein.
Cancer immunoediting: Molecular pathways to possible novel therapeutic interventions (2008)

Cancer immunoediting is the process by which immunity controls and shapes cancer. We originally envisaged that cancer immunoediting would occur in three phases that we termed Elimination (also known as cancer immunosurveillance, the host protective phase of the process), Equilibrium (a phase in which the outgrowth of tumor cells that survive immune destruction is kept in check resulting in a state of functional tumor dormancy) and Escape (the phase where tumor growth can no longer be immunologically controlled and becomes clinically apparent either because of immune sculpting of the cancer cell population or because the tumor cells have induced in the host a state of immunologic unresponsiveness). Strong experimental data has now been obtained using mouse models of cancer demonstrating the existence of each phase of the process and compelling clinical data suggests that a similar process may also occur during the evolution of certain types of human cancer as well. Our recent work has focused on identifying the molecules and cells that participate in elimination, equilibrium and escape. This work has led to the identification of specific cytokines (such as the interferons) and cytokine receptor signaling pathways (such as the JAK-STAT pathway) that, in some cases, promote immune effector mechanisms that result in cancer control while, in other cases, induce an immunosuppressive state that promotes tumor escape and results in uncontrolled tumor growth. We are currently exploring whether we can influence the eventual outcome of the cancer immunoediting process by therapeutically enhancing or inhibiting the expression and/or action of specific cytokines.

This abstract was published in Cancer Immunity , a [Cancer Research Institute][1] journal that ceased publication in 2013 and is now provided online in association with Cancer Immunology Research .

 [1]: http://cancerresearch.org/
Differential Endometrial Cell Sensitivity to a Cholesterol-Dependent Cytolysin Links Trueperella pyogenes to Uterine Disease in Cattle1 (2014)

Purulent disease of the uterus develops in 40% of dairy cows after parturition, when the epithelium of the endometrium is disrupted to expose the underlying stroma to bacteria. The severity of endometrial pathology is associated with isolation of Trueperella pyogenes. In the present study, T. pyogenes alone caused uterine disease when infused into the uterus of cattle where the endometrial epithelium was disrupted. The bacterium secretes a cholesterol-dependent cytolysin, pyolysin (PLO), and the plo gene was identical and the plo gene promoter was highly similar amongst 12 clinical isolates of T. pyogenes. Bacteria-free filtrates of the T. pyogenes cultures caused hemolysis and endometrial cytolysis, and PLO was the main cytolytic agent, because addition of anti-PLO antibody prevented cytolysis. Similarly, a plo-deletion T. pyogenes mutant did not cause hemolysis or endometrial cytolysis. Endometrial stromal cells were notably more sensitive to PLO-mediated cytolysis than epithelial or immune cells. Stromal cells also contained more cholesterol than epithelial cells, and reducing stromal cell cholesterol content using cyclodextrins protected against PLO. Although T. pyogenes or plo-deletion T. pyogenes stimulated accumulation of inflammatory mediators, such as IL-1beta, IL-6, and IL-8, from endometrium, PLO did not stimulate inflammatory responses by endometrial or hematopoietic cells, or in vitro organ cultures of endometrium. The marked sensitivity of stromal cells to PLO-mediated cytolysis provides an explanation for how T. pyogenes acts as an opportunistic pathogen to cause pathology of the endometrium once the protective epithelium is lost after parturition.
The Patient-Specific Brace Design and Biomechanical Analysis of Adolescent Idiopathic Scoliosis (2009)

Brace application has been reported to be an effective approach in treating mild to moderate idiopathic adolescent scoliosis. However, little attention is focused on the biomechanical study of patient-specific brace treatment. The purpose of this study was to propose a design method of personalized brace and to analyze its biomechanical behavior and to compare the brace forces with the I-Scan measurement system. Based on a three-dimensional patient-specific finite element model of the spine, rib cage, pelvis, and abdomen, a parametric patient-specific model of a thoracolumbosacral orthosis was built. The interaction between the torso and the brace was modeled by surface-to-surface contact interface. Three standard strap tensions (20 N, 40 N, and 60 N) were loaded on the back of the brace to simulate the strap tension. The I-Scan distribution pressure measurement system was used to measure the different region pressures, and the equivalent forces in these regions were calculated. The spinal curve changes and the forces acted on the brace generated by the strap tension were evaluated and compared with the measurement. The reduction in the coronal curvature was about 60% for a strap tension of 60 N. The sacral slope and the lordosis were partially reduced in this case, but the kyphosis had no obvious change. The brace slightly modified the axial rotation at the apex of the scoliotic curve. The forces generated in finite element analysis were approximately in good agreement with the measurement. The design and biomechanical analysis methods of patient-specific brace should be useful in the design of more effective braces.
Design of a Superferric Dipole for the Superconducting Supercollider (1985)

The Superconducting Supercollider (SSC) is a 20TeV on
20Tev dual beam proton accelerator, which will use
superconducting magnets and whose construction is expected to begin in 1987. The Texas Accelerator Center is pursuing the superferric option for the SSC reference
design. The superferric dipole magnet consists of a
laminated iron yoke powered by a few turns of
superconductor. These dipoles have a magnetic length of
105m and a bore of 2.Scm x 3.7cm and have been designed to produce a field uniform to 1 part in 10', for fields from O.15T at an injection energy of 1TeV to 3T at a storage energy of 20TeV. Two such magnets, one for each beam, are placed in a single cryostat. The accelerator will require approximately 1,000 double dipoles. We present the cold iron version of the superferric dipole. We discuss its basic design, the design of the superconductor and its insulation, the good field size and quality, the magnetic forces and stored energy, the dimensional tolerances and errors for industrial production, and test results of several prototypes. We also describe the finite difference and finite element computer software used for the design.
False-positive HIV-1 virus cultures using whole blood (1992)

Swiss National Centre for Retroviruses, Institute of Medical Virology, University of Zurich, Cloriastrasse 30, CH-8028 Zurich, Switzerland.
Filter wheel equalization for chest radiography: A computer simulation (1995)

A chest radiographic equalization system using lung-shaped templates mounted on filter wheels is under development. Using this technique, 25 lung templates for each lung are available on two computer controlled wheels which are located in close proximity to the x-ray tube. The large magnification factor (> 10X) of the templates assures low-frequency equalization due to the blurring of the focal spot. A low-dose image is acquired without templates using a (generic) digital receptor, the image is analyzed, and the left and right lung fields are automatically identified using software developed for this purpose. The most appropriate left and right lung templates are independently selected and are positioned into the field of view at the proper location under computer control. Once the templates are positioned, acquisition of the equalized radiographic image onto film commences at clinical exposure levels. The templates reduce the exposure to the lung fields by attenuating a fraction of the incident x-ray fluence so that the exposure to the mediastinum and diaphragm areas can be increased without overexposing the lungs. A data base of 824 digitized chest radiographs was used to determine the shape of the specific lung templates, for both left and right lung fields. A second independent data base of 208 images was used to test the performance of the templates using computer simulations. The template shape characteristics derived from the clinical image data base are demonstrated. The detected exposure in the lung fields on conventional chest radiographs was found to be, on average, three times the detected exposure behind the diaphragm and mediastinum.(ABSTRACT TRUNCATED AT 250 WORDS)
Towards resource-efficient cloud systems: Avoiding over-provisioning in demand-prediction based resource provisioning (2016)

Demand-prediction based resource provisioning schemes help assure service level objectives (SLO) in cloud systems. We notice that if a provisioning scheme does not exclude bursts from historical resource demands in normal demand prediction or always uses a large padding to correct under-prediction, it will lead to resource over-provisioning and low resource utilization. To improve the previous schemes, in this paper, we present a Resource-efficient Predictive Resource Provisioning system in clouds (RPRP) that excludes bursts in demand prediction and has algorithms to specifically handle bursts to avoid resource over-provisioning. Rather than setting padding to a possibly high value, RPRP has a load-dependent padding algorithm that adaptively determines padding based on predicted demands. To handle bursts, RPRP embodies a responsive padding algorithm that adaptively adjusts padding to recover from both under-provisioning and over-provisioning. We implemented RPRP on top of Xen and conducted both trace-driven simulation and real-world testbed experiments. The experimental results show that RPRP achieves higher resource utilization, more accurate demand predictions, and fewer SLO violations than previous schemes.
Developmental Expression of Three Forms of Gonadotropin-Releasing Hormone and Ontogeny of the Hypothalamic-Pituitary-Gonadal Axis in Gilthead Seabream (Sparus aurata)1 (2004)

To address the complexity of the origin of the GnRH system in perciforms, we investigated the ontogenic expression of three GnRHs in gilthead seabream. Using in situ hybridization, chicken (c) GnRH-II mRNA-expressing cells were detected in the hindbrain at 1.5 days postfertilization (DPF) and in the midbrain at 2 DPF and thereafter; the hindbrain signals became undetectable after 10 DPF. Salmon (s) GnRH mRNA-expressing cells were first seen in the olfactory placode at 3 DPF, started caudal migration at 14 DPF, and reached the preoptic areas at 59 DPF. Seabream (sb) GnRH mRNA-expressing cells were first detected in the terminal nerve ganglion cells (TNgc), ventral part of the ventral telencephalon, nucleus preopticus parvocellularis, and thalamus at 39 DPF, and extended to the nucleus preopticus magnocellularis at 43 DPF, ventrolateral hypothalamus at 51 DPF, and nucleus lateralis tuberis and posterior tuberculum at 59 DPF. Coexpression of sbGnRH and sGnRH transcripts was found in the TNgc. Using real-time fluorescence-based quantitative polymerase chain reaction, transcript levels of cGnRH-II and sGnRH were first detected at 1 and 1.5 DPF, respectively, and increased and remained high thereafter. Transcript levels of sbGnRH remained low after first detection at 1 DPF. Furthermore, these GnRH expression profiles were correlated with the expression profiles of reproduction-related genes in which at least four concomitant increases of GnRH, GnRH receptor, gonadotropin, gonadotropin receptor, and Vasa transcripts were found at 5, 8, 14, and 28 DPF. Our data provide an expanded view of the ontogeny of the GnRH system and reproductive axis in perciforms.
Determination of total flavone in manufacture of beesglue (2000)

Flavone extracted from manufacture of bessglue in 70% C 2H 5OH by ultrasonic wave reacted with Al 3+ , colour complex was obtained with rutin as sample, the weight percentage of flavone was determinated by spectrophotometry.
A gate array chip set as a fault-tolerant bus interface unit based on nubus protocols (1990)

Even with the performance of microprocessors expected to double within the next three to five years, the processing power increase offered by parallel processing has made multiprocessor systems very cost-effective. Each module in the multiprocessor systems will typically include a processor, coprocessor, cache, and main memory. This kind of architecture has generated the system-on-aboard distributed-intelligence concept, and the 32-bit multimaster buses thus come into play since these high-performance systems need to communicate with each other. During communication, commands and large blocks of data are transmitted across the bus. Along with the multiprocessor system, the single-CPU system continues to need a fast bus and wide data path to serve as a common I/O interface for terminals, disk storage devices, communication, and memory boards. With the board size limited, the trend toward distributed intelligence increases the need to place more functions on a single board, and therefore bus interface unit (BIU) integrated circuits (ICs) play an important role in the design of new boards. Spaceborn systems must be fault-tolerant due to their high susceptibility to transient faults and the high costs of repair and maintenance. Hence, a gate array fault-tolerant bus-interface IC based on modified NuBus protocols is designed to meet these requirements. The gate array IC design system HIGHLAND from United Technologies Microelectronics Center is used, along with other CAD tools such as the Berkeley VLSI Tool Set and LOGEN to generate a layout for the BIU. Two programs are written to interface the necessary CAD tools. All the circuits are designed and simulated on a VAXstation 3200 (Ultrix-32) and VAX11/785 (VMS).
A Classification of Action Origami as Systems of Spherical Mechanisms (2013)

Action origami is a field of origami dealing with models that are folded so that in their final, deployed state they exhibit motion. Hundreds of action origami models exist, many of which use complicated kinematics to achieve motion in their deployed state. A better understanding of the mechanisms used to create motion in action origami could be a foundation for developing a new source of concepts for deployable, movable engineering solutions. This brief presents an approach for evaluating and classifying the mechanisms that enable action origami motion. Approximately 130 action origami models are investigated. Although disguised with artistic elements, it is found that most action origami models are based on a few fundamental mechanisms. A classification scheme is proposed, and an unexplored class of action origami is identified as an area for future origami art.
Smart Mining for Deep Metric Learning (2017)

To solve deep metric learning problems and producing feature embeddings, current methodologies will commonly use a triplet model to minimise the relative distance between samples from the same class and maximise the relative distance between samples from different classes. Though successful, the training convergence of this triplet model can be compromised by the fact that the vast majority of the training samples will produce gradients with magnitudes that are close to zero. This issue has motivated the development of methods that explore the global structure of the embedding and other methods that explore hard negative/positive mining. The effectiveness of such mining methods is often associated with intractable computational requirements. In this paper, we propose a novel deep metric learning method that combines the triplet model and the global structure of the embedding space. We rely on a smart mining procedure that produces effective training samples for a low computational cost. In addition, we propose an adaptive controller that automatically adjusts the smart mining hyper-parameters and speeds up the convergence of the training process. We show empirically that our proposed method allows for fast and more accurate training of triplet ConvNets than other competing mining methods. Additionally, we show that our method achieves new state-of-the-art embedding results for CUB-200-2011 and Cars196 datasets.
Expression of Pluripotent Stem Cell Markers in the Human Fetal Testis (2007)

Human primordial germ cells (PGCs) have proven to be a source of pluripotent stem cells called embryonic germ cells (EGCs). However, the developmental potency of these cells in the fetal gonad still remains elusive. Thus, this study provides a comprehensive analysis of pluripotent and germ cell marker expression in human fetal testis 7-15 weeks postfertilization (pF) and compares this expression to their ability to derive EGCs. Although the majority of germ cells expressed stem cell markers stage-specific embryonic antigen (SSEA) 1, SSEA4, EMA-1, and alkaline phosphatase, only a small percentage of those (<1%) expressed OCT4, CKIT, and NANOG. Specifically, the number of OCT4(+)/CKIT(+)/NANOG(+) cells significantly increased in the developing cords during weeks 7-9, followed by a gradual decline into week 15 pF. By week 15 pF, the remaining OCT4(+)/CKIT(+)/NANOG(+) cells were found in the cords surrounding the periphery of the testis, and the predominant germ cells, CKIT(+) cells, no longer expressed OCT4 or NANOG. Based on morphology and early germ cell marker expression, including VASA, PUM2, and DAZL, we suggest these cells are mitotically active gonocytes or prespermatogonia. Importantly, the number of OCT4(+) cells correlated with an increase in the number of EGC colonies derived in culture. Interestingly, two pluripotent markers, Tra-1-60 and Tra-1-81, although highly expressed in EGCs, were not expressed by PGCs in the gonad. Together, these results suggest that PGCs maintain expression of pluripotent stem cell markers during and after sexual differentiation of the gonad, albeit in very low numbers.