gebhart/patrepeval huggingface dataset:
Conceptual Study for Open Energy Systems: Distributed Energy Network Using Interconnected DC Nanogrids (2015)

We describe the general concept and practical feasibility of a dc-based open energy system (OES) that proposes an alternative way of exchanging intermittent energy between houses in a local community. Each house is equipped with a dc nanogrid, including photovoltaic panels and batteries. We extend these nanogrids with a bidirectional dc-dc converter and a network controller so that power can be exchanged between houses over an external dc power bus. In this way, demand-response fluctuations are absorbed not only by the local battery, but can be spread over all batteries in the system. By using a combination of voltage and current controlled units, we implemented a higher-level control software independent from the physical process. A further software layer for autonomous control handles power exchange based on a distributed multiagent system, using a peer-to-peer like architecture. In parallel to the software, we made a physical model of a four-node OES on which different power exchange strategies can be simulated and compared. First results show an improved solar replacement ratio, and thus a reduction of ac grid consumption thanks to power interchange. The concept's feasibility has been demonstrated on the first three houses of a full-scale OES platform in Okinawa.
Relationship of Human Sperm Acrosin and Proacrosin to Semen Parameters. I. Comparisons Between Symptomatic Men of Infertile Couples and Asymptomatic Men, and Between Different Split Ejaculate Fractions (1982)

Acrosin is a sperm serine proteinase whose activity appears to be essential for fertilization in mammals, although this has not been shown in man due to experimental limitations. The present study shows that the concentrations of acrosin and its precursor, proacrosin, are significantly higher (P <0.001) in the spermatozoa of asymptomatic men (those having no seminal abnormalities or known fertility impairments) than of symptomatic men (those from infertile couples showing at least one abnormal seminal parameter). It is demonstrated additionally that the spermatozoa of the first fraction of split ejaculates contain significantly greater quantities of acrosin and proacrosin when compared to the spermatozoa from the second fraction of the same split ejaculates (P <0.001). The fertility potential of the first fraction is generally accepted to be greater than that of the second fraction. These data, together with our earlier findings on the acrosin and proacrosin content of fresh and cryopreserved human spermatozoa (Goodpasture et al, 1981), suggest that subfertility or infertility in man may be related to a low acrosini proacrosin content of spermatozoa.
Role of procalcitonin and CRP in diagnosis and follow-up of neonatal sepsis. (2007)

We aimed to investigate the role of procalcitonin in the diagnosis and follow-up of neonatal sepsis, and to compare it with C-reactive protein (CRP) in this context. Between April and October 2002, a total of 67 neonates were randomly recruited into the study and were divided into four groups as: those with highly probable sepsis (group 1), probable sepsis (group 2), possible sepsis (group 3), and no sepsis (group 4; controls). When the initial procalcitonin levels of the groups were compared, the results were statistically significant (p < 0.05) except for the comparison between groups 3 and 4 (p > 0.05). When the initial CRP levels were compared between the groups, the levels measured in groups 1 and 2 were significantly higher than the levels measured in groups 3 and 4 (p < 0.05). In addition, the decreasing levels in procalcitonin were statistically more significant than the decreasing levels in CRP in showing the response to antibiotic treatment (p < 0.01 and p < 0.05, respectively). In conclusion, serum procalcitonin levels seemed to be superior to serum CRP levels in terms of early diagnosis of neonatal sepsis, in detecting the severity of the illness, and in evaluation of the response to antibiotic treatment.
Inhibition of the assembly and secretion of procollagen by incorporation of a threonine analogue, hydroxynorvaline. (1975)

Hydroxynorvaline (DL-alpha-amino-beta-hydroxyvaleric acid) was shown to competitively inhibit the activation of threonine and valine when tested with tRNA and synthetases prepared from whole chick embryos. However, the hydroxynorvaline was transferred only to threonyl-tRNA and not valyl-tRNA. The hydroxynorvaline had no effect when tested with other amino acids. The Km for threonine was 25 muM and the Ki for hydroxynorvaline was 181 muM. When fibroblasts from embryonic chick tendons were incubated with [3H]threonine and increasing concentrations of hydroxynorvaline, there was a progressive decrease in the incorporation of [3H]threonine so that 1 mM hydroxynorvaline the incorporation into nondialyzable protein was 26% of the control value. A much smaller decrease in the incorporation of other radioactive amino acids was observed. When the cells were incubated hith [14C]proline and 1 mM hydroxynorvaline, the labeled procollagen containing hydroxynorvaline accumulated intracellularly and very little was secreted. Control experiments demonstrated that free hydroxynorvaline did not inhibit the secretion of unsubstituted procollagen. Although the individual pro alpha chains containing hydroxynorvaline were of normal molecular weight (125,000) and hydroxyproline content, only about 50% of this intracellularly retained procollagen was triple helical within the cell as 37 degrees as measured by sensitivity to pepsin digestion. Also only approximately 50% of the pro alpha chains were disulfide-linked to form triple stranded molecules as compared to greater than 85% linkage in unsubstituted procollagen. We postulate that incorporation of hydroxynorvaline alters the conformation of the propeptide extension sufficiently so that: (a) normal assembly of disulfide-linked, triple helical molecules is reduced and (b) assembled triple helical molecules are not properly recognized by the secretory mechanism.
The effect of different implant neck configurations on soft and hard tissue healing: a randomized-controlled clinical trial (2010)

implants with a reduced height turned neck of 1.8 mm may, indeed, lower the crestal bone resorption and hence, may maintain higher crestal bone levels than do implants with a 2.8 mm turned neck, when sunk to the same depth. Moreover, several factors other than the vertical positioning of the moderately rough SLA surface may influence crestal bone levels after 1 year of function.
Phase Separation of Mixed-Composition Self-Assembled Monolayers into Nanometer Scale Molecular Domains (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhase Separation of Mixed-Composition Self-Assembled Monolayers into Nanometer Scale Molecular DomainsS. J. Stranick, A. N. Parikh, Y.-T. Tao, D. L. Allara, and P. S. WeissCite this: J. Phys. Chem. 1994, 98, 31, 7636–7646Publication Date (Print):August 1, 1994Publication History Published online1 May 2002Published inissue 1 August 1994https://pubs.acs.org/doi/10.1021/j100082a040https://doi.org/10.1021/j100082a040research-articleACS PublicationsRequest reuse permissionsArticle Views2026Altmetric-Citations303LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The relationship of human papillomavirus-related cervical tumors to cigarette smoking, oral contraceptive use, and prior herpes simplex virus type 2 infection. (1996)

It has now been established that infection with human papillomavirus (HPV) is necessary for the development of most cervical cancers. HPV is not sufficient for the development of cancer. Other exposures or host factors are necessary for cancer to occur. As part of an ongoing, population-based case-control study of invasive cervical cancer, we investigated the role of cigarette smoking, oral contraceptive (OC) use, and herpes simplex virus type 2 (HSV-2) as potential cofactors with HPV in the development of cervical cancer. Residents of three counties in western Washington State who were diagnosed with invasive squamous cell cervical cancer (n = 314) from January 1986 through December 1992 were interviewed about their sexual, reproductive, contraceptive, and cigarette smoking histories. Similar information was obtained from control women identified through random digit dialing (n = 672). The sera from 206 cases and 522 controls were tested for both HPV 16 capsid antibodies and HSV-2 antibodies. PCR was used to test paraffin-embedded tumor tissues for the presence of HPV DNA types 6, 16, 18, 31, 33, 35, and 39. Women with cervical cancer were more likely to be current smokers at diagnosis than population controls [relative risk (RR), 2.5; 95% confidence interval (CI), 1.8-3.4]. The risk associated with smoking was present to a similar extent among women positive and negative for HPV as measured by HPV 16 capsid antibodies and HPV DNA in the tumor tissue (cases). OC use was only important if first use was at an early age, particularly ages < or = 17 years (RR, 2.3; 95% CI, 1.4-3.8). There was only a slight risk for cervical cancer associated with antibodies to HSV-2 (RR, 1.2; 95% CI, 0.9-1.7). However, when we stratified by markers of HPV exposure, we found a significant increase in risk associated with HSV-2 among women negative for HPV 16 antibodies (RR, 2.0; 95% CI, 1.3-3.0), which was strengthened when we confined our analysis to cases whose tumors were HPV DNA negative (RR, 3.6; 95% CI, 1.6-8.0). There was no indication that cigarette smoking, OC use, or HSV-2 infection influence the ability of HPV infection to cause invasive cervical cancer. OC use may only be important in the etiology of invasive squamous cell cervical tumors if the use occurs at a critical time in the development of a woman's reproductive tract, at ages < or = 17 years. The majority of risk associated with HSV-2 was confined to HPV-negative tumors, indicating a possible separate pathway to disease that may account for 5-10% of invasive cervical cancers.
Inhibitory effect of E-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on herpes simplex virus replication and DNA synthesis (1982)

The effect of E-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU) on herpes simplex virus (HSV) replication was examined and compared with that of E-5-(2-bromovinyl)-2'-deoxyuridine (BVdUrd). The 50% inhibitory dose against HSV type 1 (HSV-1) was 0.1 microgram/ml compared with 0.008 microgram/ml for BVdUrd; the antimetabolic 50% inhibitory dose of BVaraU ranged from 20 to 95 micrograms/ml. The addition of 50 micrograms of BVaraU per ml to HSV-1-infected Vero cells decreased the synthesis of viral and cellular DNA by 37 and 28%, respectively. The 5'-triphosphate (BVaraUTP) competed with dTTP in DNA synthesis by the herpes-viral and cellular DNA polymerases; the apparent Ki values of HSV-1 DNA polymerase, DNA polymerase alpha, and DNA polymerase beta were 0.14, 0.32, and 5 microM, respectively. Thus, BVaraU was a less effective antiherpesvirus agent than BVdUrd; unlike BVdUrd, it did not appear to be internally incorporated into replicating DNA in virus-infected cells.
Investigating the Use of Children's Artwork as an Observation Tool in Early Reading Programs. (2000)

This is a report on research conducted over the past six years on the relationship between children's art and reading levels. Findings from one study in Grenada primary schools and three in Ontario suggest that children's picture-making is governed more by mind than hand, and that there may be common cognitive skills, gender and age effects, and traits that affect reading and art. Background, Objectives, and Previous Related Investigations Perhaps the place to begin this paper is in clarifying what it is not. It is not about justi fying the place of art in school programs, nor about integrating the visual and lan guage arts. It is about considering pupils' artworks as manifestations of thoughts and performance styles?as windows for teach ers in primary level reading programs. It reviews selected references pertaining to connections between reading and art and to the content and organization of young children's pictures in addressing the ques tion of whether their artwork can provide useful information for reading instruction. Incentive for the investigation evolved from my own preliminary studies and in terest over decades in debate among art educators about children's artistic devel opment (Lowenfeld & Brittain, 1975), art as communication/language (Cohen & Gainer, 1984; Dorn, 1999), and art as cog nitive activity ( Dorn, 1999; Nelson et al, 1998). The research question was also in spired by Gardner's theory of multiple intelligences (1983), and conjecture that artistic works provide a visible display of many of these, as well as the maker's ac quired knowledge, experience and skill with media, and approach to tasks. What brought these together at the outset was an opportunity to study paintings made by young children in Grenada schools, and to collaborate with their visiting reading in structor. We were aware that her new pu pils were mainly emergent and early read ers who had almost no experience with art materials either at home or school, and we wondered if their first crayoned and painted pictures would provide useful knowledge about both subject areas. A principle hy pothesis for the research that followed was that there would be some similar qualities to and antecedents for their art and lan
Immunotherapeutic effectiveness of BCG inactivated by various modalities (1980)

Factors responsible for the limited effectiveness of Bacillus Calmette-Guérin (BCG) immunotherapy are completely understood. One limitation is that although the effect is dose-related, high-dose administration increases the risk of BCG toxicity, possibly the result of disseminated BCG infection. In the present study, we compared the relative effectiveness of Tice lyophilized BCG which was inactivated by heat, sonication, irradiation, streptomycin, or isoniazid (INH). The model systems were the 13762A rat mammary adenocarcinoma and the line 10 guinea pig hepatoma. In the 13762A system, tumor were injected on day 7 with living or killed BCG preparations, or with Corynebacterium parvum as a positive control. Tumors were excised on day 20. Rats treated with surgery alone usually died within 40--50 days with extensive metastases to lymph nodes, lungs, and viscera. Guinea pig line 10 hepatoma was treated with vaccine containing irradiated tumor cells and BCG. In both the rat and guinea pig models, BCG inactivated by means of irradiation was effective as viable BCG and heat-killed BCG also had a strong effect. Streptomycin treatment diminished the efficacy of the BCG and sonication destroyed BCG effectiveness even though the organisms were not all killed. The INH treatment of tumor-bearing rats did not alter the benefits of single or repeated injections of high-dose viable BCG, irradiated BCG, or C parvum. We conclude that inacativation of BCG with heat, irradiation, or INH host treatment preserves but does not improve the immunotherapeutic benefits of BCG.
Air handling control of a diesel engine with a complex dual-loop EGR and VGT air system using MPC (2015)

In this paper, the development of a multivariable control system based on Model Predictive Control (MPC) is described and experimentally validated for a diesel engine with a complex dual-loop Exhaust Gas Recirculation (EGR) and Variable Geometry Turbocharger (VGT) air handling system. This air architecture is required to meet the stringent emissions and fuel economy requirements for this engine. The air system is a multi-input multi-output nonlinear system that makes the design and tuning of the controller challenging. In this paper, a switched linear MPC with feed-forward and feedback control architecture is developed for the system. The presented design process is systematic, modular, and model-based leading to a considerable reduction in the development and calibration time of the control system. A significant improvement is also observed with respect to a well-tuned feed-forward controller. The design process and the performance of the controller are demonstrated experimentally in the engine test cell using Matlab/SIMULINK software and dSPACE rapid prototyping tool.
Functional Domain Mapping and Selective Trans-dominant Effects Exhibited by Cx26 Disease-causing Mutations (2004)

Mutations in Cx26 are a major cause of autosomal dominant and recessive forms of sensorineural deafness. Some mutations in Cx26 are associated not only with deafness but also with skin disease. We examined the subcellular localization and function of two green fluorescent protein (GFP)-tagged Cx26 point mutants that exhibit both phenotypes, G59A-GFP and D66H-GFP. D66H-GFP was retained within the brefeldin A-insensitive trans-Golgi network, whereas a population of G59A-GFP was transported to the cell surface. Neither G59A nor D66H formed gap junctions that were permeable to small fluorescent dyes, suggesting they are loss-of-function mutations. When co-expressed with wild-type Cx26, both G59A and D66H exerted dominant-negative effects on Cx26 function. G59A also exerted a trans-dominant negative effect on co-expressed wild type Cx32 and Cx43, whereas D66H exerted a trans-dominant negative effect on Cx43 but not Cx32. We propose that the severity of the skin disease is dependent on the specific nature of the Cx26 mutation and the trans-dominant selectivity of the Cx26 mutants on co-expressed connexins. Additional systematic mutations at residue D66, in which the overall charge of this motif was altered, suggested that the first extracellular loop is critical for Cx26 transport to the cell surface as well as function of the resulting gap junction channels.
The Effect of Temperature of Test on Abrasion Resistance by the Pico Method (1969)

Abstract The following conclusions may be reached from the results:
The Struggle for Babel and Bible. Introductory.—Eduard Koenig.—A Prominent Theologian's View.—M. Halevy's Opinion.—A Roman Catholic Verdict.—Cornill on " Babel and Bible."—The German Emperor in His New Role as a Theologian.—The Emperor William's Letter. (1903)

CORDIAL as the reception extended by the American public to Delitzsch's book Babel and Bible has been, it is only remotely comparable to the favor bestowed upon it by the reading public of Germany.
Treatment of Alzheimer's disease with cholinergic drugs. (1991)

Several cholinergic drugs have been experimentally used to treat the cognitive and behavioral deficits associated with Alzheimer's disease. Unfortunately the results have been somewhat disappointing. The cholinergic drugs are also prone to produce serious side effects. Experience with these drugs lead us to conclude that cholinergic drugs alone may not be the answer to treat Alzheimer disease patients. There seems to be a need to develop drug(s) which could affect several neurotransmitter or neuromodulator systems. Neuroendocrine changes induced by these drugs may be useful biological markers in estimating their central effects.
Maximizing Wind Turbine Energy Capture Using Multivariable Extremum Seeking Control (2009)

Maximizing energy capture has become an important issue as more turbines are installed in low wind areas. This paper investigates the application of extremum seeking control (ESC) to maximizing the energy capture of variable speed wind turbines. The optimal control torque and pitch angle are searched via ESC based on the measurement of the rotor power. The advantage of this method is the independency from accurate turbine modelling and wind measurement. Simulation was conducted on FAST for a wind turbine dynamic model, under smooth, turbulent and field recorded wind profiles. The simulation results demonstrated significant improvement in energy capture compared to the standard control with fixed reference. An anti-windup ESC was applied to overcome the integral windup due to actuator saturation which would otherwise disable the ESC process. Finally, the integrator and high-pass filter resetting schemes were applied to improve the transient under the abrupt changes of wind.
Contaminant Removal from Oxygen Production Systems for In Situ Resource Utilization (2012)

The In Situ Resource Utilization (ISRU) project has been developing technologies to produce oxygen from lunar regolith to provide consumables to a lunar outpost. The processes developed reduce metal oxides in the regolith to produce water, which is then electrolyzed to produce oxygen. Hydrochloic and hydrofluoric acids are byproducts of the reduction processes, as halide minerals are also reduced at oxide reduction conditions. Because of the stringent water quality requirements for electrolysis, there is a need for a contaminant removal process. The Contaminant Removal from Oxygen Production Systems (CROPS) team has been developing a separation process to remove these contaminants in the gas and liquid phase that eliminates the need for consumables. CROPS has been using Nafion, a highly water selective polymeric proton exchange membrane, to recover pure water from the contaminated solution. Membrane thickness, product stream flow rate, and acid solution temperature and concentration were varied with the goal of maximizing water permeation and acid rejection. The results show that water permeation increases with increasing solution temperature and product stream flow rate, while acid rejection increases with decreasing solution temperature and concentration. Thinner membranes allowed for higher water flux and acid rejection than thicker ones. These results were used in the development of the hardware built for the most recent Mars ISRU demonstration project.
Random projection trees and low dimensional manifolds (2008)

We present a simple variant of the k-d tree which automatically adapts to intrinsic low dimensional structure in data without having to explicitly learn this structure.
Über Verbindungen mit Urotropin‐Struktur, XXXIX. Eine neue, ergiebige Synthese des Adamantan‐Ringsystems (1968)

Abstract Eine neue, ergiebige Synthese des Adamantan‐Ringsystems führt ausgehend von dem Enamin aus 4‐Oxo‐cyclohexan‐dicarbonsäure‐(1.1)‐diäthylester mit Pyrrolidin durch Kondensation mit α‐Brommethyl‐acrylsäure‐äthylester in einem schritt zu 2.6‐Dioxo‐adamantan‐dicarbon‐säure‐(1.3)‐diäthylester ( 4 ), der durch Reduktion in mehreren Schritten in 2‐Hydroxy‐adamantan‐dicarbonsäure‐(1.3) ( 12 ) umgewandelt wurde.
Synthesis of isocoumarins via indanones (1976)

R. H. Carter (<em xmlns="http://www.rsc.org/schema/rscart38">neé</em> Rayner), R. M. Colyer, R. A. Hill and J. Staunton, J. Chem. Soc., Perkin Trans. 1, 1976, 1438 DOI: 10.1039/P19760001438