gebhart/patrepeval huggingface dataset:
Abnormal left ventricular intracavitary flow acceleration in patients undergoing aortic valve replacement for aortic stenosis. A marker for high postoperative morbidity and mortality. (1992)

Abnormal intracavitary flow acceleration after aortic valve replacement for severe aortic stenosis is associated with a distinctive ventricular geometry and supernormal systolic function but not systolic anterior motion of the mitral valve. Such flow acceleration appears to be a marker for increased postoperative morbidity and mortality. Preoperative and postoperative Doppler echocardiography may be useful in risk stratification and guiding therapy.
Hybrid Q-switched laser with Ti-indiffused LiNbO<sub>3</sub>and Er-Yb co-doped glass waveguides (1997)

We report the design and characterization of a novel Q-switched laser configuration based on a composite Er/sup +3/-Yb/sup +3/ co-doped ion-exchanged glass and Ti-indiffused LiNbO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> waveguides. This 1536 nm Q-switched laser provides stable 200 ns wide optical pulses for a cavity length of 7 m with a peak power of 13.5 W and a pulse energy of 2.7 μJ at a 2-kHz repetition rate and 180 mW of 980-nm pump power. Also, we examine the dependence of the pulsewidth and peak power on the laser cavity length to estimate the performance of the integrated version of such a laser.
The Multiple Roles of Myelin Protein Genes During the Development of the Oligodendrocyte (2009)

It has become clear that the products of several of the earliest identified myelin protein genes perform functions that extend beyond the myelin sheath. Interestingly, these myelin proteins, which comprise proteolipid protein, 2',3'-cyclic nucleotide 3'-phosphodiesterase and the classic and golli MBPs (myelin basic proteins), play important roles during different stages of oligodendroglial development. These non-myelin-related functions are varied and include roles in the regulation of process outgrowth, migration, RNA transport, oligodendrocyte survival and ion channel modulation. However, despite the wide variety of cellular functions performed by the different myelin genes, the route by which they achieve these many functions seems to converge upon a common mechanism involving Ca(2+) regulation, cytoskeletal rearrangements and signal transduction. In the present review, the newly emerging functions of these myelin proteins will be described, and these will then be discussed in the context of their contribution to oligodendroglial development.
Particular shape of the tongue and benign migratory glossitis. (2018)

A 33-year-old male patient comes to our observation for a slight discomfort in the left side of the tongue. The patient reported good general health and that he have sometimes taken benzodiazepine in periods of stress. The dental abrasion showed the presence of bruxism. On an objective examination we could notice the simultaneous presence of a "toothed tongue" and a slightly area of erosion on the left side of the dorsal tongue, with an irregular white halo around it. This lesion, appeared from some days, is symptomatic. The diagnosis is compatible for benign migratory glossitis. The patient claimed to have never suffered of skin diseases strongly related to migratory glossitis. It is possible that the bruxism may have determined the presence of that lateral tongue shape and that stress may be the main cause of the appearance of migratory glossitis. The simultaneous presence of the two conditions has never been documented in the scientific literature and we do not exclude that there may be a correlation to the genesis of both lesions. Sometimes the presence of a tongue with this morphology could be the result of a trauma or a surgery. The lingual erosion can be placed in differential diagnosis with a heat burn or a chemical burn.
Imageable Antigen‐Presenting Gold Nanoparticle Vaccines for Effective Cancer Immunotherapy In Vivo (2012)

Goldnanopartikel (AuNPs) wurden mit einem rot fluoreszierenden Protein (RFP, rosafarbene Formen im Bild) als Modellantigen und einem Oligonukleotid (CpG), das die Immunantwort stimuliert, funktionalisiert. Diese AuNPs ermöglichten bei Verwendung als Krebsimpfstoffe in einem Tumormodell den effizienten Transport eines Antigens zum Zielort, die Verfolgung des Impfstoffs mithilfe nichtinvasiver klinischer Bildgebung sowie Vorbeugung und Behandlung von Krebs.
Design of Monolithic Step-Up DC-DC Converters with On-Chip Inductors (2011)

This thesis presents the design of a step-up DC-DC converter with on-chip coupled inductors. Circuit theory of DC-DC converters in general is presented, after which a mathematical model of a step up converter is developed. A circuit implementation optimized from results of the mathematical model follows. For a completely integrated step-up converter, the inductor size is reduced by increasing the frequency of operation and using a circuit topology that employs coupled inductors. Spiral inductors are also studied to achieve maximum quality factor and inductance. A fast PWM control system is used to regulate the high-frequency converter. The fabrication was done in standard TSMC 0.18-$\\mu$m digital CMOS process for four circuits, including one with a conventional topology and the others with a coupled inductor topology with varying inductor geometries. Measurement results from a fabricated prototype have been presented, demonstrating the functionality of the four circuits with coupled inductors on the fabricated chip and the improvement of the coupled solution over the conventional design. It is demonstrated that the circuits with coupled inductors have a significant improvement in performance based on conversion ratio and efficiency. Finally, the design process is evaluated and recommendations are made for future work. Furthermore, a new self-oscillating and robust control system is proposed that enables simpler and more efficient regulation for high-frequency converters such as one developed for this thesis.
Evaluation of elastic properties and temperature effects in Si thin films using an electrostatic microresonator (2003)

Laterally driven microresonators were used to estimate the temperature-dependent elastic modulus of single-crystalline Si for microelectromechanical systems (MEMS). The resonators were fabricated through surface micromachining from silicon-on-glass wafers. They were moved laterally by alternating electrostatic force at a series of frequencies, and then a resonance frequency was determined, under temperature cycling in the range of 25°C to 600°C, by detecting the maximum displacement. The elastic modulus was obtained in the temperature range by Rayleigh's energy method from the detected resonance frequency. At this time, the temperature dependency of elastic modulus was affected by surface oxidation as well as its intrinsic variation: a temperature cycle permanently reduces the resonance frequency. The effect of Si oxidation was analyzed for thermal cycling by applying a simple composite model to the measured frequency data; here the oxide thickness was estimated from the difference in the resonance frequency before and after the temperature cycle, and was confirmed by field-emission scanning electron microscopy. Finally, the temperature coefficient of the elastic modulus of Si in the <110> direction was determined as -64×10/sup -6/[°C/sup -1/]. This value was quite comparable to those reported in previous literatures, and much more so if the specimen temperature is calibrated more exactly.
Terrylenediimide:  A Novel Fluorophore for Single-Molecule Spectroscopy and Microscopy from 1.4 K to Room Temperature (1997)

The photophysical properties of terrylenediimide (TDI) make this novel fluorophore an ideal candidate for single-molecule studies in solid matrices using various optical techniques. By employing frequency selective high-resolution laser spectroscopy at liquid helium temperatures, we could isolate the fluorescence excitation lines of single TDI molecules. Additionally, vibrational modes of the molecule were examined and the population and depopulation rates of the triplet state determined. At temperatures between 100 K and room temperature single TDI molecules were imaged by confocal fluorescence microscopy. In these investigations one-step irreversible bleaching and “on−off” transitions of the fluorescence were observed.
Enantioselektive Katalyse; 92. Mitteilung. Optisch aktive Dendrimerphosphine mit verzweigten Pyridinbausteinen (1995)

Two-layer phosphines were synthesised by reaction of optically active metalated pyridine amines with 1,2-bis(dichlorophosphino)ethane. The optically active pyridine amines were obtained from the corresponding secondary optically active amines and 4-bromo-2,6-bis(dibromomethyl)pyridine.
Photovoltaic manufacturing technology, Phase 1 (1992)

This report examines manufacturing multiple-band-gap, multiple- junction solar cells and photovoltaic modules. Amorphous silicon alloy material is deposited (using microwave plasma-assisted chemical vapor deposition) on a stainless-steel substrate using a roll-to-roll process that is continuous and automated. Rapid thermal equilibration of the metal substrate allows rapid throughput of large-area devices in smaller production machines. Potential improvements in the design, deposition, and module fabrication process are described. Problems are also discussed that could impede using these potential improvements. Energy Conversion Devices, Inc. (ECD) proposes cost and time estimates for investigating and solving these problems. Manufacturing modules for less than $1.00 per peak watt and stable module efficiencies of greater than 10% are near-term goals proposed by ECD. 18 refs.
Vertebral Bone Marrow Perfusion Evaluated with Dynamic Contrast-enhanced MR Imaging: Significance of Aging and Sex (2001)

Rate of vertebral bone marrow perfusion revealed a significant decrease in subjects older than 50 years. Women demonstrated a higher marrow perfusion rate than men younger than 50 years and a more marked decrease than men older than 50 years.
Steroids. VI.<sup>1</sup> The Wohl—Ziegler Bromination of Steroidal 1,4-Dien-3-ones. Partial Synthesis of ▵<sup>6</sup>-Dehydroestrone and Equilenin (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSteroids. VI.1 The Wohl—Ziegler Bromination of Steroidal 1,4-Dien-3-ones. Partial Synthesis of ▵6-Dehydroestrone and EquileninSt. Kaufmann, J. Pataki, G. Rosenkranz, J. Romo, and Carl DjerassiCite this: J. Am. Chem. Soc. 1950, 72, 10, 4531–4534Publication Date (Print):October 1, 1950Publication History Published online1 May 2002Published inissue 1 October 1950https://pubs.acs.org/doi/10.1021/ja01166a054https://doi.org/10.1021/ja01166a054research-articleACS PublicationsRequest reuse permissionsArticle Views430Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Potash recovery from process and waste brines by solar evaporation and flotation (1984)

The Bureau of Mines investigated energy-efficient methods for recovering potash values from process and waste brines. Laboratory pan evaporation of four chloride brines produced crude salts containing predominantly sylvite, halite, and carnallite. Six sulfate-chloride brines produced crude salts containing primarily schoenite, kainite, leonite, sylvite, carnallite, and halite. Potash grades ranged from 7.2 to 22.2% K/sub 2/O, and recoveries from 84 to 99%. Sylvite flotation from chloride evaporites, with amine collector, recovered 90 to 97% of the potash in a concentrate containing 54.3 to 60.3% K/sub 2/O. Fatty acid flotation of the high-sulfate evaporite recovered 78% of the sulfate minerals in a 27.8%-K/sub 2/O concentrate. Flotation of the chloride minerals with amine collector recovered 80% of the potash in a 59.7%-K/sub 2/O concentrate. Solar evaporation of 10,000 gal of brine recovered 99% of the potash in a crude evaporite containing 24.5% schoenite and 20 pct sylvite. Continuous flotation in a 100-lb/h process research unit recovered over 95% of the potash in schoenite and sylvite concentrates containing 28.0 and 62.3% K/sub 2/O, respectively. An economic evaluation suggested a rate of return of 3% for a new facility and 9% if the process is adapted to fit an existing plant.
EDO: Improving Read Performance for Scientific Applications through Elastic Data Organization (2011)

Large scale scientific applications are often bottlenecked due to the writing of checkpoint-restart data. Much work has been focused on improving their write performance. With the mounting needs of scientific discovery from these datasets, it is also important to provide good read performance for many common access patterns, which requires effective data organization. To address this issue, we introduce Elastic Data Organization (EDO), which can transparently enable different data organization strategies for scientific applications. Through its flexible data ordering algorithms, EDO harmonizes different access patterns with the underlying file system. Two levels of data ordering are introduced in EDO. One works at the level of data groups (a.k.a process groups). It uses Hilbert Space Filling Curves (SFC) to balance the distribution of data groups across storage targets. Another governs the ordering of data elements within a data group. It divides a data group into sub chunks and strikes a good balance between the size of sub chunks and the number of seek operations. Our experimental results demonstrate that EDO is able to achieve balanced data distribution across all dimensions and improve the read performance of multidimensional datasets in scientific applications.
Effect of the Osmotic Pressure of the Growth Medium on <i>fabB</i> Mutants of <i>Escherichia coli</i> (1974)

Temperature-sensitive, unsaturated fatty acid (fabB) auxotrophs of Escherichia coli can grow at the restrictive temperature in the absence of unsaturated fatty acid in a medium with a high osmotic pressure. If a mutant culture was starved for unsaturated fatty acids and harvested just before the lysis started, the fatty acid composition of the cells was the same as that of cells grown until late log phase in a high-osmotic medium. Evidence is presented that the in vivo unsaturated fatty acid biosynthesis is significantly increased in a high osmotic medium. The increase is probably due to a partial activation of the temperature-sensitive fabB product. Besides the stimulation of the temperature-sensitive fabB product, a minimal osmotic pressure of the medium appeared to be necessary to allow growth of cells containing lipids with a changed fatty acid composition. fabA mutants are unable to grow in a high-osmotic medium in the absence of unsaturated fatty acids. No increase in the in vivo unsaturated fatty acid biosynthesis could be detected in the temperature-sensitive fabA mutants.
The Chemistry of Indoles. CIII. Simple Syntheses of Serotonin, N-Methylserotonin, Bufotenine, 5-Methoxy-N-methyltryptamine, Bufobutanoic Acid, N-(Indol-3-yl)methyl-5-methoxy-N-methyltryptamine, and Lespedamine Based on 1-Hydroxyindole Chemistry. (2001)

Application of regioselective nucleophilic substitution reactions of 1-hydroxytryptamines to novel and simple syntheses of serotonin (1a), N-methylserotonin (1b), bufotenine (1c), 5-methoxy-N-methyltryptamine (2a), bufobutanoic acid (3a), N-(indol-3-yl)methyl-5-methoxy-N-methyltryptamine (4), and lespedamine (5) are described. Effective syntheses of 5-benzyloxytryptamine and 1-methoxy-2-oxindoles are also reported.
Eliminating the need of serum testing using low serum culture conditions for human bone marrow-derived mesenchymal stromal cell expansion (2013)

The low serum concentration in Panserin 401 supplemented with growth factors enables the use of defined, invariable, non-synthetic FBS for the isolation and expansion of hMSC. The required hMSC characteristics like surface marker expression and differentiation capacity are maintained. Importantly, no differences in the cell proliferation could be detected. Therefore, using these low-serum culture conditions, the need for lot-to-lot pre-testing of FBS usually needed for optimal hMSC expansion is abolished leading to long-term consistency and comparability of results.
Benzazepinone calcium channel blockers. 2. Structure activity and drug metabolism studies leading to potent antihypertensive agents. Comparison with benzothiazepinones (1992)

As part of a program to discover potent antihypertensive analogues of diltiazem (3a), we prepared 1-benzazepin-2-ones (4). Benzazepinones competitively displace radiolabeled diltiazem, and show the same absolute stereochemical preferences at the calcium channel receptor protein. Derivatives of 4 containing a trifluoromethyl substituent in the fused aromatic ring show potent and long-acting antihypertensive activity. Studies of the metabolism of 4 lead to the metabolically stable antihypertensive calcium channel blockers 5a and 5c. Benzazepinone 5a is a longer acting and more potent antihypertensive agent than the second generation diltiazem analogue TA-3090 (3e).
Proposed Revision of the Standard Fire Insurance Policy with Special Reference to Moral Hazard Clauses (1937)

George W. Goble, Proposed Revision of the Standard Fire Insurance Policy with Special Reference to Moral Hazard Clauses, Journal of the American Association of University Teachers of Insurance, Vol. 4, No. 1, Proceedings of the Fourth Annual Meeting (Mar., 1937), pp. 37-54
Implementation of switched-current FIR filter using distributed arithmetic technique: exploitation of digital concept in analogue domain (2005)

Recently, a distributed arithmetic (DA) technique has been employed in digital implementation of finite impulse response (FIR) filters, since it can significantly reduce hardware resources at the cost of higher clock frequency. In this paper, we show that the concept of DA can be efficiently exploited in an analogue domain. Specifically, a switched-current (SI) FIR filter is realized based upon the concept of DA. In addition, it is revealed that the DA SI FIR filter offers extended maximum achievable resolution normally dictated by transistor matching. The technique also helps reduce silicon area and power requirements. Two examples of FIR filter design according to WCDMA and cdma2000 specifications are presented to demonstrate the feasibility of the novel technique. Simulation results are shown to confirm the circuit functions.
Windows Me annoyances (2001)

Preface 1. Making the Most of Windows Me What's Wrong with Windows The Windows Family Tree Transition to Windows Me 2. Basic Explorer Coping Skills Coping with Explorer Tweaking the Interface Regaining Control of the Desktop 3. The Registry Getting to Know the Registry Editor Behind the Scenes: Hives and DAT Files Backing Up the Registry Restoring a Corrupted Registry Using Registry Patches Finding the Right Registry Key Automating the Deletion of Registry Items Search the Registry Effectively Compacting the Registry Using INI Files Understanding File Types Registry Tools 4. Tinkering Techniques Cleaning Up the Desktop Files and Folders Making Windows Your Own 5. Maximizing Performance Removing Software Bottlenecks Fine-Tuning and Upgrading Hardware Components Transfer Windows onto Another Hard Disk 6. Troubleshooting General Troubleshooting Techniques Dealing with Drivers and Other Tales of Hardware Troubleshooting Error Messages Preventive Maintenance and Data Recovery 7. Networking and Internetworking Setting Up a Workgroup Connecting to the Internet Dealing with Dialing Mixing and Matching Networks and Other Tricks of the Trade Security and Multiple Users 8. Taking Control of Web Integration The Lowdown on Web Integration Components Make Good Use of the Web View Using the Active Desktop Choosing Your Browser Defaults 9. Scripting and Automation Building a Script with VBScript Running Applications from Scripts Accessing the Registry from Scripts Manipulating Files from Scripts Creating Windows and Internet Shortcuts in Scripts Networking with Scripts Manipulating Internet Explorer from Scripts Using Command-Line Parameters in Scripts Writing CGI Scripts for a Web Server Making a Startup Script Deciphering Script Errors Finding a Better Editor Further Study Automating Scripts with Scheduled Tasks Wacky Script Ideas A. Setting Locator B. DOS Resurrected C. Class IDs of System Objects Index
Length control of an optical resonator using second-order transverse modes (2014)

We present the analysis of an unorthodox technique for locking a laser to a resonant optical cavity. Error signals are derived from the interference between the fundamental cavity mode and higher-order spatial modes of order two excited by mode mismatch. This scheme is simple, inexpensive, and, in contrast to similar techniques, first-order insensitive to beam jitter. After mitigating sources of technical noise, performance is fundamentally limited by quantum shot noise.
Wound debridement: Comparative reliability of three methods for measuring fibrin percentage in chronic wounds (2010)

The purpose of this study was to examine the intra- and interrater reliability of three methods to measure the percentage of fibrin within a wound, hence reflecting wound debridement. The three methods include visual assessment, a portable wound measurement system (PWMS) Visitrak(R), and a computerized planimetry software Canvas(R). The main objective was to compare the computerized planimetry with visual analysis. For each wound, a series of two repeated recordings of fibrin percentage based on the same Day 1 photograph at Day 8 and Day 15, respectively, was assessed by four evaluators using the two methods. Additional objectives consisted in the assessment of the inter-rater reliability of computerized planimetry and PWMS to assess fibrin percentage and total surface area. Twenty-four patients were included for a total of 31 wounds. Intraclass correlation coefficient revealed improved reproducibility and repeatability of computerized planimetry. The reproducibility of computerized planimetry was better than PWMS when measuring the percentage of fibrin and total wound area. Because average visual estimations were very close to the computerized planimetry, bedside evaluation of fibrin percentage and wound debridement was considered as reliable, and consequently a valid technique for daily practice. PWMS proved to be less convenient, owing to difficulties in identifying fibrin margins. The higher intra and interrater reliability of computerized planimetry probably reflected the fact that subjective clinical assessment and objective calculation of percentages were mandatory for correct wound evaluation. Therefore, digital image analysis was considered as an accurate method for double-blind and multicentric trials.
Selection, Training, and Supervision of Field Interviewers in Marketing Research (1948)

Vergil D. Reed, Katherine G. Capt, Herbert A. Vitriol, Selection, Training, and Supervision of Field Interviewers in Marketing Research, The American Statistician, Vol. 2, No. 3 (Jun., 1948), pp. 15-20