gebhart/patrepeval huggingface dataset:
Magnetic fluids guidebook : properties and applications (1990)

Magnetic fluid as a colloidal suspension with magnetic particles properties of magnetic fluids applications of magnetic fluids computational principles of magnetic fluid seals.
Survival in acute myeloid leukemia is associated with NKp44 splice variants (2016)

NKp44 is a receptor encoded by the NCR2 gene, which is expressed by cytokine-activated natural killer (NK) cells that are involved in anti-AML immunity. NKp44 has three splice variants corresponding to NKp44ITIM+ (NKp44-1) and NKp44ITIM- (NKp44-2, and NKp44-3) isoforms. RNAseq data of AML patients revealed similar survival of NKp46+NKp44+ and NKp46+NKp44- patients. However, if grouped according to the NKp44 splice variant profile, NKp44-1 expression was significantly associated with poor survival of AML patients. Moreover, activation of PBMC from healthy controls showed co-dominant expression of NKp44-1 and NKp44-3, while primary NK clones show more diverse NKp44 splice variant profiles. Cultured primary NK cells resulted in NKp44-1 dominance and impaired function associated with PCNA over-expression by target cells. This impaired functional phenotype could be rescued by blocking of NKp44 receptor. Human NK cell lines revealed co-dominant expression of NKp44-1 and NKp44-3 and showed a functional phenotype that was not inhibited by PCNA over-expression. Furthermore, transfection-based overexpression of NKp44-1, but not NKp44-2/NKp44-3, reversed the endogenous resistance of NK-92 cells to PCNA-mediated inhibition, and resulted in poor formation of stable lytic immune synapses. This research contributes to the understanding of AML prognosis by shedding new light on the functional implications of differential splicing of NKp44.
Fire protection design criteria (1997)

This Standard provides supplemental fire protection guidance applicable to the design and construction of DOE facilities and site features (such as water distribution systems) that are also provided for fire protection. It is intended to be used in conjunction with the applicable building code, national Fire Protection Association Codes and Standards, and any other applicable DOE construction criteria. This Standard, along with other delineated criteria, constitutes the basic criteria for satisfying DOE fire and life safety objectives for the design and construction or renovation of DOE facilities.
Ferroelectric properties of form I perdeuteriated poly(vinylidene fluoride) (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFerroelectric properties of form I perdeuteriated poly(vinylidene fluoride)Y. Takase, Hajime Tanaka, T. T. Wang, R. E. Cais, and J. M. KometaniCite this: Macromolecules 1987, 20, 9, 2318–2320Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://pubs.acs.org/doi/10.1021/ma00175a049https://doi.org/10.1021/ma00175a049research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations (1999)

Esophageal cancer is the third most prevalent gastrointestinal malignancy in the world. The tumor responds poorly to various therapeutic regimens and the genetic events underlying esophageal carcinogenesis are not well understood. To identify overall chromosomal aberrations in esophageal squamous cell carcinoma, we performed comparative genomic hybridization (CGH). All 17 tumor samples were found to exhibit multiple gains and losses involving different chromosomal regions. The frequency of chromosomal loss associated with this type of tumor was as follows: in 2q (100%), 3p (100%), 13q (100%), Xq (94%), 4 (82%), 5q (82%), 18q (76%), 9p (76%), 6q (70%), 12q (70%), 14q (65%), 11q (59%), and 1p (53%). Interstitial deletions on 1p, 3p, 5q, 6q, 11q, and 12q were detected also. Chromosomal gains were displayed by chromosomes and chromosome areas: 19 (100%), 20q (94%), 22 (94%), 16p (65%), 17 (59%), 12q (59%), 8q (53%), 9q (53%), and 3q (50%). Two sites showing apparent amplification were 11q (70%) and 5p15 (47%). To validate the CGH data, we isolated a BAC clone mapping to 18q12.1. This clone was used as a probe in interphase fluorescence in situ hybridization of tumor touch preparations and allelic loss was clearly revealed. This study represents the first whole-genome analysis in esophageal squamous cell carcinoma for associated chromosomal aberrations that may be involved in either the genesis or progression of this malignancy.
Motion compensated refinement for low complexity pixel based distributed video coding (2006)

Distributed video coding (DVC) is a new coding paradigm that enables to exploit video statistics, partially or totally at the decoder. A particular case of DVC, Wyner-Ziv coding, deals with lossy source coding with side information at the decoder and allows a shift of complexity from the encoder to the decoder, theoretically without any penalty in the coding efficiency. The Wyner-Ziv solution here described encodes each video frame independently (intraframe coding), but decodes the same frame conditionally (interframe decoding). At the decoder, and compensation tools are responsible to obtain an accurate interpolation of the original frame using previously decoded (temporally adjacent) frames. This paper proposes a novel approach to improve the performance of pixel domain Wyner-Ziv video coding by using a motion compensated refinement of the decoded frame and use it as improved side information. More precisely, upon partial decoding of each frame, the decoder refines its motion trajectories in order to achieve a better reconstruction of the decoded frame.
[Rapid counting of bacteria isolated from cattle, swine and sheep carcasses using the resazurin method]. (1984)

A rapid counting method has been used to estimate the microbial flora of beef, pork and sheep. The test used in this study permitted a 3 h counting of the bacteria whatever their origin. The easiness of the test makes it feasible for the appreciation of the hygienic conditions existing during the slaughtering operations.
Devising wastewater treatment strategies (1993)

Troubleshooting a waste water treatment system takes basic knowledge of how the process is designed to work, tools, and a few resources. This paper describes a Seven Steps Program employed fopr troubleshooting. A well-designed troubleshooting program should be comprehensive, thoroughly tested and constantly revisited to maintain a reliable and efficient wastewater treatment system. Such a method includes each of the integral components including biological, human, mechanical, and chemical. This total systems approach can result in improved system operation and better bottom line results.
Deep vein thrombosis during chemotherapy in a patient with advanced testicular cancer: Successful percutaneous thrombectomy under temporary placement of retrievable inferior vena cava filter (2001)

A 27-year-old man with advanced testicular cancer experienced two events of deep vein thrombosis (DVT) during three cycles of cisplatin-based combination chemotherapy; the first thrombotic event occurred in the inferior vena cava (IVC) following the initial two cycles of chemotherapy and the second thrombotic event occurred in the right iliac vein following the third cycle. For both thrombotic events, he was successfully managed with thrombolytic therapy and percutaneous thrombectomy using a transcatheter hydraulic thrombectomy device under temporary placement of a retrievable IVC filter. Stasis of the IVC due to compression by a retroperitoneal lymphadenopathy of 7 cm in diameter, which was demonstrated on computed tomographic scans at presentation, was considered a major cause of DVT during chemotherapy. Patients with bulky retroperitoneal disease causing stasis of major veins are at high risk of DVT associated with chemotherapy and thromboprophylaxis should be strongly considered during their chemotherapy.
A 2-D Micromachined SOI MEMS Mirror With Sidewall Electrodes for Biomedical Imaging (2010)

This paper presents a 2 DOF silicon-on-insulator (SOI) microelectromechanical systems (MEMS) mirror with sidewall (SW) electrodes for biomedical imaging. The MEMS mirror is actuated by electrostatic actuators, and the mirror plate is 1000 μm × 1000 μm with a thickness of 35 μm. The paper analyzes the effects of the single-crystal serpentine torsion bar width and bottom electrodes and SW electrodes on the performance of the micromirror. A new fabrication process based on SOI wafer, hybrid bulk/surface micromachined technology, and a high aspect-ratio shadow mask is presented. In comparison to the previous fabrication process and the Optical iMEMS process, the process is novel, easily understood, and simple to realize. Static and dynamic experiments indicate that a MEMS mirror with SW can provide a large scanning angle under low-drive voltage. The MEMS mirror is developed for a confocal MACROscope system for biomedical imaging. This mirror is also well suited for applications where large linear angular scan at low-driving voltage is required.
New Life for an Old Drug: the Anthelmintic Drug Niclosamide Inhibits Pseudomonas aeruginosa Quorum Sensing (2012)

The need for novel antibacterial strategies and the awareness of the importance of quorum sensing (QS) in bacterial infections have stimulated research aimed at identifying QS inhibitors (QSIs). However, clinical application of QSIs identified so far is still distant, likely due to their unsuitability for use in humans. A promising way to overcome this problem is searching for anti-QS side activity among the thousands of drugs approved for clinical use in the treatment of different diseases. Here, we applied this strategy to the search for QSIs, by screening a library of FDA-approved compounds for their ability to inhibit the QS response in the Gram-negative pathogen Pseudomonas aeruginosa. We found that the anthelmintic drug niclosamide strongly inhibits the P. aeruginosa QS response and production of acyl-homoserine lactone QS signal molecules. Microarray analysis showed that niclosamide affects the transcription of about 250 genes, with a high degree of target specificity toward the QS-dependent regulon. Phenotypic assays demonstrated that niclosamide suppresses surface motility and production of the secreted virulence factors elastase, pyocyanin, and rhamnolipids, and it reduces biofilm formation. In accordance with the strong antivirulence activity disclosed in vitro, niclosamide prevented P. aeruginosa pathogenicity in an insect model of acute infection. Besides the finding that an FDA-approved drug has a promising antivirulence activity against one of the most antibiotic-resistant bacterial pathogens, this work provides a proof of concept that a lateral anti-QS activity can be detected among drugs already used in humans, validating a new approach to identify QSIs that could easily move into clinical applications.
A hybrid framework for surface registration and deformable models (2002)

In computer vision, two complementary approaches have been widely used to perform object reconstruction and registration. The deformable model framework locally applies internal and external forces to fit 3D data. The non-rigid registration framework iteratively computes the best global transformation that minimizes the distance between a template and the data. In this paper first we show that applying a global transformation on a surface model, is equivalent to applying an external force on a deformable model without any regularizing force. Second we propose a hybrid framework that combines the registration framework and the deformable models framework. Our hybrid deformation approach allows us to control the scale at which the model is deformed. This is clearly beneficial for performing both reconstruction and registration tasks. We show examples of this approach on active contours and deformable surfaces. Furthermore, a global transformation based on axial symmetry is introduced.
Trends in Global Philanthropy Among U.S. Foundations: A Brief Review of Data and Issues (2011)

· International grantmaking has increased dramatically in the past two decades, at a rate faster than domestic grantmaking. · The increase in international grantmaking, stimulated by increased interest in global issues, was fueled by increased foundation assets and especially by new foundations created since 1990. · While many of the issues confronting international grantmaking exist with domestic grantmaking, they have special aspects and increased importance because of the global context. · Many foundations have now accumulated information about how best to work in partnership with other foundations, governments, and business; these lessons would benefit all foundations. · Thoughtful collective action taken by foundation membership organizations from across the globe would likely result in constructive advances in effectiveness, and increased public benefit.
Etude mécanique des films de nitrure de silicium fortement contraints utilisés pour augmenter les performances des transistors CMOS (2009)

Cette etude porte sur la caracterisation physique, chimique et mecanique de films minces de nitrure de silicium. Ces films sont utilises pour accroitre les performances des transistors en induisant une deformation dans le canal. Pour ce faire les films sont fortement contraints par les conditions de depots. Pour ameliorer encore plus les performances des transistors, la contrainte du film a ete augmentee en utilisant des films multicouches avec traitement plasma. Ce traitement engendre une desorption d'hydrogene permettant la recombinaison de nouvelles liaisons Si-N, conduisant a l'augmentation de la contrainte. Lors de cette premiere phase de densification, on constate par ailleurs que le module de Young augmente aussi bien dans plan que hors-plan. Ensuite, si le traitement se prolonge, la desorption s'arrete et on constate une deuxieme phase au cours de laquelle la porosite du film diminue fortement. Cette diminution semble correlee a l'accroissement superieur du module de Young dans le plan par rapport a celui hors-plan, conduisant a une anisotropie du film. On suppose donc que les pores sont de forme colonnaire dans la direction hors-plan.
A cytologic method of diagnosis of carcinoma of the colon (1960)

Summary The problem of diagnosing carcinoma of the colon is presented and current diagnostic technics are reviewed. The desirability of a screening test for colonic carcinoma is discussed. A method of recovering malignant cells from enema returns without instrumentation is presented. Clinical evaluation suggests that this method is accurate in detecting malignant cells of neoplasms of the colon and it appears to be a useful screening test for carcinoma of the colon.
VIP17/MAL, a lipid raft-associated protein, is involved in apical transport in MDCK cells (1999)

Apical proteins are sorted and delivered from the trans-Golgi network to the plasma membrane by a mechanism involving sphingolipid-cholesterol rafts. In this paper, we report the effects of changing the levels of VIP17/MAL, a tetraspan membrane protein localized to post-Golgi transport containers and the apical cell surface in MDCK cells. Overexpression of VIP17/MAL disturbed the morphology of the MDCK cell layers by increasing apical delivery and seemingly expanding the apical cell surface domains. On the other hand, expression of antisense RNA directed against VIP17/MAL caused accumulation in the Golgi and/or impaired apical transport of different apical protein markers, i.e., influenza virus hemagglutinin, the secretory protein clusterin (gp80), the transmembrane protein gp114, and a glycosylphosphatidylinositol-anchored protein. However, antisense RNA expression did not affect the distribution of E-cadherin to the basolateral surface. Because VIP17/MAL associates with sphingolipid-cholesterol rafts, these data provide functional evidence that this protein is involved in apical transport and might be a component of the machinery clustering lipid rafts with apical cargo to form apical transport carriers.
The Study of a New Concept of Low-Damage Fracturing Technology In Low-Permeability Exploration Wells (2005)

Abstract In low permeable exploration wells, how to minimize formation damage and fracture damage is regarded as an unique goal of hydraulic fracturing design and treatment. Sometimes, an inappropriate fracturing design may even decrease an exploration well's oil production potential as a result of high damage within both formation and fracture, so that an error decision-making may be determined. Therefore, a new fracturing technology of low damage for exploration wells is put forward in the paper, compared with the past conventional fracturing technology, the highlights of the new technology includes:A new concept of damage is established and demonstrated, it contains not only damage as just mentioned above but also excessive fracture height growth, inappropriate proppant propped pattern and so on;utilizing the newly developed fracturing fluids such as slick water, low concentration of densifier, linear gel (not cross linked), low molecular weight fluid, etc.; optimizing the minimum viscosity of fracturing fluid, then optimizing the corresponding pumping rate;studying the optimum combination of fracturing fluid types and that of proppant type and size in the course of fracturing treatment;Studying the sensitivity of formation damage and fracture damage to the post-fracturing performance, which may be used to select fracturing treatment parameters inversely;one of the main optimization target is to minimize fracture propagation length after shut-in so as to obtain an optimized propped profile;studying the mechanism of water blockage during the course of fracturing treatment and the countermeasures correspondingly. What's more, above fracturing technology has been put in to field applications and an expected result has also been obtained, so it has a great significance in improving fracturing technology, reservoir evaluation and reservoir development as well.
Simulation 3D des structures de combustion préhistoriques (2009)

National audience
Digital Predistortion Using a Vector-Switched Model (2012)

A switched behavioral model considering memory effects with a special focus on “difficult” amplifier architectures is proposed in this paper. The proposed model is shown to be very low-complex and linearly identifiable. A digital predistorter based on the proposed model is implemented for a 100-W 2.6-GHz Doherty power amplifier that has been considered difficult in other reports, and it is shown that the proposed models can successfully linearize the amplifier, both for a WCDMA signal and a more wideband long-term evolution signal. In particular, the proposed model and the digital predistorter is shown to outperform other state-of-the-art models and digital predistorters in terms of computational complexity for a given desired accuracy.
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response (2017)

Microglia are increasingly implicated in brain pathology, particularly neurodegenerative disease, with many genes implicated in Alzheimer's, Parkinson's, and motor neuron disease expressed in microglia. There is, therefore, a need for authentic, efficient in vitro models to study human microglial pathological mechanisms. Microglia originate from the yolk sac as MYB-independent macrophages, migrating into the developing brain to complete differentiation. Here, we recapitulate microglial ontogeny by highly efficient differentiation of embryonic MYB-independent iPSC-derived macrophages then co-culture them with iPSC-derived cortical neurons. Co-cultures retain neuronal maturity and functionality for many weeks. Co-culture microglia express key microglia-specific markers and neurodegenerative disease-relevant genes, develop highly dynamic ramifications, and are phagocytic. Upon activation they become more ameboid, releasing multiple microglia-relevant cytokines. Importantly, co-culture microglia downregulate pathogen-response pathways, upregulate homeostatic function pathways, and promote a more anti-inflammatory and pro-remodeling cytokine response than corresponding monocultures, demonstrating that co-cultures are preferable for modeling authentic microglial physiology.
A microfluid test-bed with nanopore membranes for in-vitro simulation of flow characteristics of glaucoma drainage devices (2002)

In this paper, we report on a microfluidic test-bed for in-vitro simulation of flow characteristics of valved-glaucoma drainage devices. A nanopore membrane is used to mimic the fibrous tissue encapsulation of the sub-conjunctival plate following surgery. Pressure measurements with and without the valve clearly demonstrated the persisting effect of the microvalve in regulating the intraocular pressure subsequent to the fibrous capsule formation.
Testing a zone plate with a grating interferometer (1990)

The physical theory, of testing optics by the Ronchi sine grating interferometer is developed. In the experiment a sine grating splits the third-order wavefront of the zone plate under test into three displaced wavefronts, which then interfere with one another to form interference fringes. The intensity distribution of the interference pattern can be recorded for various positions of the sine grating. By subtracting the contribution of the inherent diffractive aberration of the sine grating, the value of the spherical aberration associated with the third-order wavefront of the zone plate under test can be determined. Theory and experiment are compared.
Chinese Jurisprudence and Hong Kong Law (2009)

On 1 July 1997, Hong Kong, a colony (euphemistically called dependent territory) of Britain, was returned to the fold of the motherland, China, as a Special Administration Region, with a high degree of autonomy. Ten years on, we find that the common law system established by the British in Hong Kong, as guaranteed by the Basic Law, survived and thrived. A cursory review of legal and social science literature shows that there is little scholarly discourse or public debate on the proper jurisprudence standards to be applied in the making and evaluation of Hong Kong legislation. This research raises a most fundamental policy qua jurisprudence issue: Should Hong Kong law be formulated, applied or evaluated with indigenous legal standards and local jurisprudence principles, based on Asian values, Chinese culture and/or Hong Kong ethos? In so doing, this article questions the appropriateness and challenges the legitimacy of adopting Western jurisprudence principles in shaping and evaluating the Hong Kong legal system, especially after 1 July 1997.