gebhart/patrepeval huggingface dataset:
A Novel Quantum Cost Efficient Reversible Full Adder Gate in Nanotechnology (2010)

Reversible logic has become one of the promising research directions in low power dissipating circuit design in the past few years and has found its applications in low power CMOS design, cryptography, optical information processing and nanotechnology. This paper presents a novel and quantum cost efficient reversible full adder gate in nanotechnology. This gate can work singly as a reversible full adder unit and requires only one clock cycle. The proposed gate is a universal gate in the sense that it can be used to synthesize any arbitrary Boolean functions. It has been demonstrated that the hardware complexity offered by the proposed gate is less than the existing counterparts. The proposed reversible full adder gate also adheres to the theoretical minimum established by the researchers.
Synthetic neomycin-kanamycin phosphotransferase, type II coding sequence for gene targeting in mammalian cells (2005)

The bacterial neomycin-kanamycin phosphotransferase, type II enzyme is encoded by the neo gene and confers resistance to aminoglycoside drugs such as neomycin and kanamycin-bacterial selection and G418-eukaryotic cell selection. Although widely used in gene targeting in mouse embryonic stem cells, the neo coding sequence contains numerous cryptic splice sites and has a high CpG content. At least the former can cause unwanted effects in cis at the targeted locus. We describe a synthetic sequence, sneo, which encodes the same protein as that encoded by neo. This synthetic sequence has no predicted splice sites in either strand, low CpG content, and increased mammalian codon usage. In mouse embryonic stem cells sneo expressability is similar to neo. The use of sneo in gene targeting experiments should substantially reduce the probability of unwanted effects in cis due to splicing, and perhaps CpG methylation, within the coding sequence of the selectable marker.
A CMOS rotary encoder system based on magnetic pattern analysis with a resolution of 10b per rotation (2005)

A single-chip CMOS magnetic rotary encoder system based on magnetic pattern analysis is presented. Magnetic sensor arrays are integrated with ADCs and DSP circuits and fabricated in a standard 0.25 /spl mu/m CMOS technology. The chip detects the rotation angle within an error of /spl plusmn/0.36 degrees (10b per rotation).
Amplification of 4q21-q22 and theMXR gene in independently derived mitoxantrone-resistant cell lines (2000)

Molecular cytogenetic studies were conducted on three multidrug-resistant cancer sublines which are highly resistant to the chemotherapeutic agent mitoxantrone, an anthracenedione. The three independently selected sublines were derived by exposure to mitoxantrone or Adriamycin and do not overexpress MDR1 or MRP. Two sublines, MCF-7 AdVp3000 and MCF-7 MX, showed an amplification peak at 4q21-q22, as demonstrated by comparative genomic hybridization (CGH), while the third, S1-M1-80, did not. FISH using a whole chromosome 4 paint demonstrated multiple rearrangements involving chromosome 4 in MCF-7 AdVp3000 and MCF-7 MX, while S1-M1-80 contained only a simple reciprocal translocation. The parental cell lines had no chromosome 4 rearrangements and no copy number gain or amplification of chromosome 4. Spectral karyotyping (SKY) analysis revealed a balanced translocation, t(4;17)(q21-q22;p13) in S1-M1-80 and multiple clonal translocations involving chromosome 4 in MCF-7 AdVp3000 and MCF-7 MX. A novel cDNA, designated MXR, which encodes an ABC half-transporter and is highly overexpressed in the three sublines, was localized to chromosome 4 by somatic cell hybrid analysis. Southern blot analysis demonstrated amplification of the MXR gene in MCF-7 AdVp3000 and MCF-7 MX, but not in S1-M1-80. FISH studies with a BAC probe for MXR localized the gene to 4q21-22 in the normal chromosome 4 and revealed in both MCF-7 AdVp3000 and MCF-7 MX amplification of MXR at one translocation juncture, shown by SKY to be t(4;5)(4qter-->4cen-->4q21-22::5q13-->5qter++ +) in MCF-7 AdVp3000 and t(6;4;6;3)(6pter-->6q15::4q21-q22::hsr::6q?::3q?27-->+ ++3qter) in MCF MX; neither of the breakpoints in the partner chromosomes showed amplification by CGH. The data are consistent with the hypothesis of a transporter, presumably that encoded by the MXR gene, mediating mitoxantrone resistance. The MXR gene encodes a half-transporter and the absence of cytogenetic evidence of coamplification of other regions suggests that a partner may not be overexpressed, and instead the MXR half-transporter homodimerizes to mediate drug transport. Genes Chromosomes Cancer 27:110-116, 2000. Published 2000 Wiley-Liss, Inc.
Synthesis and spectroscopic and x-ray structural characterization and dynamic solution behavior of the neutral cobalt(II) alkoxides [Co{OC(C6H11)3}2]2.CH3OH.1/2C6H12.THF, [Co(OCPh3)2]2.n-C6H14, [Co(OSiPh3)2(THF)]2, and Co(OCPh3)2(THF)2 (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and spectroscopic and x-ray structural characterization and dynamic solution behavior of the neutral cobalt(II) alkoxides [Co{OC(C6H11)3}2]2.CH3OH.1/2C6H12.THF, [Co(OCPh3)2]2.n-C6H14, [Co(OSiPh3)2(THF)]2, and Co(OCPh3)2(THF)2Gary A. Sigel, Ruth A. Bartlett, David Decker, Marilyn M. Olmstead, and Philip P. PowerCite this: Inorg. Chem. 1987, 26, 11, 1773–1780Publication Date (Print):June 1, 1987Publication History Published online1 May 2002Published inissue 1 June 1987https://pubs.acs.org/doi/10.1021/ic00258a028https://doi.org/10.1021/ic00258a028research-articleACS PublicationsRequest reuse permissionsArticle Views533Altmetric-Citations75LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Horticulture: Pakistani pickled mango (2017)

Pickled fruit and vegetables are a common, simple and flavoursome accompaniment to meals in Pakistan.
The retinoblastoma gene product suppresses neu oncogene-induced transformation via transcriptional repression of neu. (1992)

The retinoblastoma susceptibility gene (Rb) is a tumor suppressor gene involved in the etiology of many types of human cancers. However, the molecular mechanisms involved in tumor suppression by Rb are largely unknown. The neu gene is a dominant transforming oncogene and a member of the growth factor receptor tyrosine kinase gene family. Both inactivation of the Rb gene and overexpression of the neu gene are involved in human breast and lung cancers. Therefore, it is of interest and importance to investigate the potential interactions between Rb and neu. Here we show that Rb suppresses neu-induced transformation by focus formation assays. This transformation suppression by Rb was further shown to be due to transcriptional repression of neu using Rb expressing effector plasmid and neu promoter-chloramphenicol acetyltransferase reporter gene. The cis-acting element conferring Rb-mediated repression was mapped to a recently identified novel enhancer in the neu promoter. The data indicate that the growth factor receptor neu is a target for the Rb gene product and transcriptional repression of a dominant oncogene expression may be one of the molecular mechanisms of Rb-mediated tumor suppression.
Abaloparatide (BA058), a novel human PTHrP analog, restores bone mass and strength in the aged osteopenic ovariectomized cynomolgus monkey (2014)

Searchable abstracts of presentations at key conferences on calcified tissues ISSN 2052-1219 (online)
Preparation and enhanced visible-light photocatalytic H2-production activity of CdS-sensitized Pt/TiO2 nanosheets with exposed (001) facets (2011)

CdS-sensitized Pt/TiO(2) nanosheets with exposed (001) facets were prepared by hydrothermal treatment of a Ti(OC(4)H(9))(4)-HF-H(2)O mixed solution followed by photochemical reduction deposition of Pt nanoparticles (NPs) on TiO(2) nanosheets (TiO(2) NSs) and chemical bath deposition of CdS NPs on Pt/TiO(2) NSs, successively. The UV and visible-light driven photocatalytic activity of the as-prepared samples was evaluated by photocatalytic H(2) production from lactic acid aqueous solution under UV and visible-light (λ ≥ 420 nm) irradiation. It was shown that no photocatalytic H(2)-production activity was observed on the pure TiO(2) NSs under UV and/or visible-light irradiation. Deposition of CdS NPs on Pt/TiO(2) NSs caused significant enhancement of the UV and visible-light photocatalytic H(2)-production rates. The morphology of TiO(2) particles had also significant influence on the visible-light H(2)-production activity. Among TiO(2) NSs, P25 and the NPs studied, the CdS-sensitized Pt/TiO(2) NSs show the highest photocatalytic activity (13.9% apparent quantum efficiency obtained at 420 nm), exceeding that of CdS-sensitized Pt/P25 by 10.3% and that of Pt/NPs by 1.21%, which can be attributed to the combined effect of several factors including the presence of exposed (001) facets, surface fluorination and high specific surface area. After many replication experiments of the photocatalytic hydrogen production in the presence of lactic acid, the CdS-sensitized Pt/TiO(2) NSs did not show great loss in the photocatalytic activity, confirming that the CdS/Pt/TiO(2) NSs system is stable and not photocorroded.
Energy Management in a Network of Grid-Connected Microgrids/Nanogrids Using Compromise Programming (2016)

A new multi-objective optimization model is proposed for efficient integration of a group of microgrids/nanogrids with local energy storage devices into the power grid. In this model, the individual microgrids/nanogrids can exchange power locally among each other as well as with the external electricity grid. A pricing regime is introduced in which differences in the local and grid buy and sell time-of-use prices of electricity incentivize local inter-microgrid/nanogrid exchanges of power over power exchange with the grid. A novel formulation of a multiple-objective constrained optimization is presented for solving the microgrids/nanogrids energy management problem under the proposed electricity pricing regime. This approach is based on minimization of l <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> or l <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> distances of the microgrids/nanogrids cost vector to a utopia point in the solution space. Components of the utopia point are defined as the minimum cost achievable by the corresponding microgrid/nanogrid when it always uses the favorable local buy/sell prices. The proposed optimization models are in the form of convex linear/quadratic programs without any binary or integer variables for l <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> /l <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> norms. Results of numerical simulations with on-line rolling horizon optimization of the storage device power flow decisions demonstrate the effectiveness of the proposed methods.
Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. (1998)

The variation in the prevalences of asthma, allergic rhinoconjunctivitis, and atopic-eczema symptoms is striking between different centres throughout the world. These findings will form the basis of further studies to investigate factors that potentially lead to these international patterns.
An estimate of the incidence of dark cutting beef in the United Kingdom (1988)

Dark cutting beef (DCB) is characterised by its high ultimate pH, purple black colour, firm texture and dry surface. This meat has become an economic problem because of its unacceptability to the consumer especially under normal retail conditions. Even with this economic pressure little information is available, in this country, concerning the incidence of high ultimate pH beef or the factors that could effect it. This work examines the occurrence of high ultimate pH meat (>6.0) and the effects of pre-slaughter handling.
A Note on 3-Dimensional Graphs (1995)

Tetrahedron stacking, illustrated below, is a spherical close packing that is identical to cannonball stacking. It neither dominates nor is dominated by two-dimensional k-graphing or s-graphing (discussed in my Feb 1995 Word ways article).
Unsupervised Learning of Event Classes from Video (2010)

We present a method for unsupervised learning of event classes from videos in which multiple actions might occur simultaneously. It is assumed that all such activities are produced from an underlying set of event class generators. The learning task is then to recover this generative process from visual data. A set of event classes is derived from the most likely decomposition of the tracks into a set of labelled events involving subsets of interacting tracks. Interactions between subsets of tracks are modelled as a relational graph structure that captures qualitative spatio-temporal relationships between these tracks. The posterior probability of candidate solutions favours decompositions in which events of the same class have a similar relational structure, together with other measures of well-formedness. A Markov Chain Monte Carlo (MCMC) procedure is used to efficiently search for the MAP solution. This search moves between possible decompositions of the tracks into sets of unlabelled events and at each move adds a close to optimal labelling (for this decomposition) using spectral clustering. Experiments on real data show that the discovered event classes are often semantically meaningful and correspond well with groundtruth event classes assigned by hand.
Pericellular matrix of growth plate chondrocytes: a study using postfixation with osmium-ferrocyanide. (1983)

The pericellular matrix surrounding chondrocytes from all zones of epiphyseal growth plate cartilage, as well as from articular, tracheal, and auricular cartilage, was examined using a number of variations of osmium ferrocyanide postfixation of aldehyde-fixed tissues. Comparisons were made with other fixative techniques, including ruthenium red, safranin O, and lanthanum nitrate, all of which have previously been reported to stabilize a variety of lacunar matrix components. An electron-dense material was preserved uniquely by osmium-ferrocyanide in the lacunar matrix of mid and late zone hypertrophying chondrocytes and was absent from all other zones of the growth plate as well as from the other types of cartilage examined. Because of its highly restricted distribution, this electron-dense material is hypothesized to represent a pericellular matrix component involved with either matrix calcification or metaphyseal capillary penetration. Several hypotheses are presented as to its specific composition.
Cyclic amidines derived from benz[c,d]indole and 4,5-dihydro-3H-1-benzazepine including some related compounds: Synthesis and pharmacological screening (1985)

Reactions of naphthostyril ( I ) with primary and secondary amines and titanium tetrachloride afforded cyclic amidines III-IX . Hydrogenation of I on Pd-C resulted in the 6,7,8,8a-tetrahydro derivative X which gave by treatment with sodium amide and 3-dimethylaminopropyl chloride the N-(aminoalkyl) compound XI . Reduction of I and its N-methyl derivative II with sodium amalgam in aqueous sodium hydroxide gave the 2a,3,4,5-tetrahydro derivatives XII and XIII . Reaction of XIII with sodium amide and 3-dimethylaminopropyl chloride afforded the 2a-(aminoalkyl) compound XIV . 1,3,4,5-Tetrahydro-1-benzazepin-2-one ( XV ) treated with primary amines and titanium tetrachloride gave the amidines XVI-XVIII . 3-Methyl-7,8,9,9a-tetrahydro-1 H -benz[ d,e ]isoquinoline ( XIX ) was reduced with sodium borohydride to compound XX which was alkylated with propargyl bromide to 1-methyl-2-propargyl-2,3,3a,4,5,6-hexahydro-1 H -benz[ d,e ]isoquinoline ( XXI ). An attempt to prepare the 2-(2-phenylethyl) analogue by treatment of compound XX with phenylacetyl chloride and by the following reduction with lithium aluminium hydride resulted in the open-chain amine XXII . The lactams I, II, X , and XIII showed some discoordinating, hypothermic, peripheral vasodilating, hyperglycaemic, diuretic and antiinflammatory effects. The amidines III-IX and XVI-XVIII had local anaesthetic, slight hypotensive, antiarrhythmic, peripheral myorelaxant, papaverine-like spasmolytic and thiopental potentiating effects.
PNA Fluorescent In Situ Hybridization for Rapid Microbiology and Cytogenetic Analysis (2003)

Hybridization-based assays for the detection of nucleic acids including in situ hybridization are increasingly being utilized in a wide variety of disciplines such as cytogenetics, microbiology, and histology. Generally in situ hybridization assays utilize either cloned genomic probes for the detection of DNA sequences or oligonucleotide probes for the detection of DNA or RNA sequences. Alternately, peptide nucleic acid (PNA) probes are increasingly being utilized in a variety of in situ hybridization assays (1,2). The neutral backbone of the PNA molecule allows for the PNA probes to bind to DNA or RNA under low ionic-strength conditions that will either disfavor reannealing of complimentary genomic sequences or are denaturing for RNA secondary structure but are favorable for PNA/DNA or PNA/RNA hybridization (3,4). For in situ hybridization assays, these unique properties of PNA probes offer significant advantages that allow for the development of fast, simple, and robust assays.
Effect of plasma actuator control parameters on a transitional flow (2018)

This study uses a wall-resolved implicit large eddy simulation to investigate the effects of different surface dielectric barrier discharge actuator parameters such as the geometry of the electrodes, frequency, amplitude of actuation and thermal effect. The actuator is used as a tripping device on a zero-pressure gradient laminar boundary layer flow. It is shown that the standard linear actuator creates structures like the Tollmien–Schlichting wave transition. The circular serpentine, square serpentine and spanwise actuators have subharmonic sinuous streak breakdown and behave like oblique wave transition scenario. The spanwise and square actuators cause comparably faster transition to turbulence. The square actuator adds energy into the higher spanwise wavenumber modes resulting in a faster transition compared to the circular actuator. When the Strouhal number of actuation is varied, the transition does not occur for a value below 0.292. Higher frequencies with same amplitude of actuation lead to faster transition. Small changes (<4%) in the amplitude of actuation can have a significant impact on the transition location which suggests that an optimal combination of frequency and amplitude exists for highest control authority. The thermal bumps approximating the actuator heating only shows localized effects on the later stages of transition for temperatures up to 373 K and can be ignored for standard actuators operating in subsonic regimes.
Measurement of Effective Bulk Modulus for Hydraulic Oil at Low Pressure (2012)

Oil properties are very important input parameters for the simulation of hydraulic components. Precise values of effective bulk modulus at low pressures are especially required to improve the simulation accuracy of the pumps suction side or of cavitation in pumps or valves. So far, theoretical equations to compute the effective bulk modulus of hydraulic oil have not been experimentally verified, and only poor measured data are available to calculate the effective bulk modulus at low pressure. Therefore in this paper, the theoretical equation was verified for effective bulk moduli based on measurements of pressure change as a function of volume change at low pressures, varying temperature, entrained air content, and type of state change. Furthermore, the comparison of effective bulk moduli calculated with three different methods (mass-change, volume-change, and sound-speed method) shows that the effective bulk modulus can be calculated well from the measurement results of all three methods. The calculated effective bulk moduli values show little variation among the methods. Additionally, the release pressure of dissolved air in oil and the change of the polytropic gas constant depending on the speed of volume change rate were identified in this study.
행정심판위원회의 조직법적 쟁점과 과제 (2018)

최근에 정부는 국민권익위원회 기능을 반부패ㆍ청렴 중심으로 재편하여 반부패 개혁을 보다 내실있게 추진하기 위하여 국민권익위원회 명칭을 국가청렴위원회로 변경하며, 국민권익위원회 기능에서 행정심판 기능을 분리하는 것을 내용으로 하는 ｢부패방지 및 국민권익위원회의 설치와 운영에 관한 법률개정안｣과 현행 국민권익위원회 소속으로...
Keratinocyte growth factor (KGF)-1 and -2 protein and gene expression in human gingival fibroblasts (2002)

The onset and progression of jreiodontal disease is associated with significant changes in the epithelial component of the attachment complex. From the early to the advanced stages of jreiodontal disease increased epithelial cell proliferation, migration and invasion into the surrounding connective tissue takes place. Concomitantly there is a significant increase in proinflammatory cytokine expression in jreiodontal tissue and quantitative and qualitative changes in the subgingival microflora, including an increase in gram-negative microorganisms. One of the most significant virulence factors of these bacteria is lipopolysaccharide (LPS) connected to the outer membrane. Two important growth factors controlling epithelial behavior are Keratinocyte Growth Factor-1 (KGF-1) and -2 (KGF-2). Connective tissue cells express these growth factors, but only epithelial cells respond to them. We studied the effect of proinflammatory cytokines and LPS on gingival fibroblast expression of KGF-1 and KGF-2 in vitro. Gingival fibroblasts were found to express KGF-1 and -2 in culture but only KGF-1 protein and gene expression was stimulated by serum, in a concentration-dependent manner by proinflammatory cytokines IL-1α, IL-1β, TNF-α and IL-6 and LPS isolated from Porphyromonas gingivalis and Escherichia coli. The local increase in proinflammatory cytokine expression and the accumulation of LPS in disease sites may therefore stimulate gingival fibroblast expression of KGF-1. We hypothesize that this local increase in KGF-1 expression may, via a paracrine mechanism, stimulate local epithelial cell proliferation, migration and invasion during the onset and progression of jreiodontitis.