gebhart/patrepeval huggingface dataset:
Efficient service handoff across edge servers via docker container migration (2017)

Supporting smooth movement of mobile clients is important when offloading services on an edge computing platform. Interruption-free client mobility demands seamless migration of the offloading service to nearby edge servers. However, fast migration of offloading services across edge servers in a WAN environment poses significant challenges to the handoff service design. In this paper, we present a novel service handoff system which seamlessly migrates offloading services to the nearest edge server, while the mobile client is moving. Service handoff is achieved via container migration. We identify an important performance problem during Docker container migration. Based on our systematic study of container layer management and image stacking, we propose a migration method which leverages the layered storage system to reduce file system synchronization overhead, without dependence on the distributed file system. We implement a prototype system and conduct experiments using real world product applications. Evaluation results reveal that compared to state-of-the-art service handoff systems designed for edge computing platforms, our system reduces the total duration of service handoff time by 80%(56%) with network bandwidth 5Mbps(20Mbps).
The Neuroprotection of Oxymatrine in Cerebral Ischemia/Reperfusion Is Related to Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)-Mediated Antioxidant Response: Role of Nrf2 and Hemeoxygenase-1 Expression (2011)

Cerebral ischemia-reperfusion (CI/R) injury remains a major medical problem due to the lack of effective therapies. Previous studies have shown that increasing the activity of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and gene targets in cell culture and stroke animal models is highly neuroprotective. Oxymatrine is the major quinolizidine alkaloid extracted from the root of Sophora flavescens AIT, and has been proved to be protective after ischemia in recent studies. The present study was designed to investigate the potential effect of oxymatrine in ischemia-reperfusion injury in rat's brain and to explore the possible role of oxymatrine in Nrf2 pathway. The results indicated that the ischemic infarct and edema were significantly reduced in rats that received oxymatrine, with a corresponding improvement in neurological function after CI/R. In immunohistochemistry and Western blotting analyses, Nrf2 and hemeoxygenase-1 (HO-1) were up-regulated in ischemic cortex, beginning at 6 h, peaking at 48 h and declining at 72 h after CI/R. Intraperitoneal injection of oxymatrine inhibited the production of lipid peroxidation and increased the activities of Nrf2 and HO-1 in rats brain after CI/R. Taken together, these results suggest that oxymatrine administered systemically protected brain against focal ischemia-reperfusion damage at the early stage of stroke, and that activating Nrf2/HO-1 pathway may contribute to the neuroprotective action of oxymatrine in rat focal brain ischemia-reperfusion model. Thus, treatment of stroke with oxymatrine may prevent severe consequences after brain attack.
Functional electrical stimulation of the extremities: Part 1 (1977)

Functional electrical stimulation of the extremities (FES) is a new method for the rehabilitation of paralysed paretic patients. Small, electronic stimulators are worn by the patient, who can voluntarily control the electrical currents applied to his paralysed muscle. These currents activate the disabled extremities and make them at least partially functional once more. This paper presents a short history of FES and discusses recent advances and problems in the field. A detailed account of present work with single- and multi-channel stimulation of paralysed legs is given, as well as some research data on upper extremity stimulation.
RECIBE EL PUEG PREMIO ANUAL MUJER Y PUBLICIDAD (2010)

GUADALAJARA, JAL.- POR SU INTERES Y CONTRIBUCION A LA CONSTRUCCION DE UNA IMAGEN MAS EQUITATIVA DEL SECTOR FEMENINO EN LOS MEDIOS DE COMUNICACION, LA CAMPANA PUBLICITARIA LA IGUALDAD ENTRE MUJERES Y HOMBRES: NUESTRA MANERA DE SER PUMAS, DEL PROGRAMA UNIVERSITARIO DE ESTUDIOS DE GENERO (PUEG) DE LA UNAM, OBTUVO EL PREMIO ANUAL MUJER Y PUBLICIDAD, EN LA CATEGORIA DE GRAFICOS.
Animating with expressive 3D brush strokes (animation abstract) (2000)

No abstract available.
Resistance and Susceptible Responses of<i>Arabidopsis thaliana</i>to Turnip Crinkle Virus (1993)

We describe the first system in which a hypersensitive response (HR) is observed after viral infection of Arabidopsis thaliana. Most ecotypes of Arabidopsis are highly susceptible to turnip crinkle virus (TCV); however, we developed two lines from the ecotype Dijon that exhibit dramatic differences in TCV susceptibility. Inoculation of the resistant line, Di-17, resulted in necrotic lesion formation on the inoculated leaves, Virus was restricted to these lesions, and no disease symptoms were observed on the uninoculated portions of most plants. Genes encoding the acidic pathogenesis-related (PR) proteins PR-1, PR-2, and PR-5 and the basic form of PR-3 were induced rapidly in the inoculated leaves, whereas upper, uninoculated leaves accumulated mRNA for these genes at slightly later times and to lower levels [...]
Software-assisted hardware reliability (2009)

Power constrained designs are becoming increasingly sensitive to supply voltage noise. We propose a hardware-software collaborative approach to enable aggressive operating margins: a checkpoint-recovery mechanism corrects margin violations, while a run-time software layer reschedules the program's instruction stream to prevent recurring margin crossings at the same program location. The run-time layer removes 60% of these events with minimal overhead, thereby significantly improving overall performance.
Dataset supporting the article entitled "Accurate and Stable Run-Time Power Modeling for Mobile and Embedded CPUs" (2016)

This dataset supports the article entitled "Accurate and Stable Run-Time Power Modeling for Mobile and Embedded CPUs" accepted for publication in IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems.
Fabrication of Highly Textured Fine‐Grained α‐Alumina by Templated Grain Growth of Nanoscale Precursors (2013)

[0001] textured alumina ceramics with a fine grain size were fabricated between 1400°C and 1600°C via templated grain growth ( TGG ) using fine alumina platelets (~0.6 and ~3 μm diameter) aligned by tape casting in either a 50 nm α‐ Al 2 O 3 matrix powder, or in a seeded boehmite sol. The 3 μm templates could be readily aligned by tape casting in both matrices (orientation parameters r = 0.27 and 0.18, respectively), whereas 0.6 μm diameter templates were well aligned in the seeded boehmite sol only ( r = 0.29). Improved alignment in boehmite sols is attributed to inorganic gelation, resulting in a strongly pseudo‐plastic rheology that preserves template alignment against the influence of Brownian motion. The in situ formation of fine α‐ Al 2 O 3 matrix after transformation in the seeded boehmite system results in a higher driving force for TGG and improves texture development. The combination of 3 μm templates with a seeded boehmite matrix results in extremely high texture qualities (texture fraction f = 0.97–0.99, r = 0.17) while maintaining a relatively fine grain size (5–10 μm in diameter and 1.5–3 μm in thickness). Although undoped samples can be fully textured at 1600°C, adding as little as ~0.25 wt% CaO / SiO 2 dopant improves TGG kinetics and yields full texture at 1400°C.
Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. (1991)

The resurgence of malaria in recent decades has been accompanied by the worldwide spread of resistance to chloroquine, a drug once uncontested as the first-line antimalarial agent because of its efficacy and low toxicity. Chloroquine-resistant strains of Plasmodium falciparum counter the drug by expelling it rapidly via an unknown mechanism. In the absence of explicit biochemical knowledge of this efflux mechanism, reverse genetics provides a powerful approach to the molecular basis of chloroquine resistance. Here we report genetic linkage analysis in which 85 restriction fragment length polymorphism markers were used to examine inheritance of the 14 P. falciparum chromosomes in a laboratory cross between a chloroquine-resistant and a chloroquine-sensitive parasite. Inheritance data from 16 independent recombinant progeny show that the rapid efflux, chloroquine-resistant phenotype is governed by a single locus within an approximately 400-kilobase region of chromosome 7. Identification and characterization of genes within this region should lead to an understanding of the chloroquine-resistance mechanism.
Suppression of Collisional Shifts in a Strongly Interacting Lattice Clock (2011)

Optical lattice clocks with extremely stable frequency are possible when many atoms are interrogated simultaneously, but this precision may come at the cost of systematic inaccuracy resulting from atomic interactions. Density-dependent frequency shifts can occur even in a clock that uses fermionic atoms if they are subject to inhomogeneous optical excitation. However, sufficiently strong interactions can suppress collisional shifts in lattice sites containing more than one atom. We demonstrated the effectiveness of this approach with a strontium lattice clock by reducing both the collisional frequency shift and its uncertainty to the level of 10(-17). This result eliminates the compromise between precision and accuracy in a many-particle system; both will continue to improve as the number of particles increases.
Antagonism of the Serotonin (5-HT)-2 Receptor and Insulin Sensitivity: Implications for Atypical Antipsychotics (2005)

The selective 5-HT2 antagonist ketanserin impaired insulin sensitivity. This effect was possibly mediated by suppression of 5-HT(2A) receptor mediated glucose uptake in skeletal muscle.
SND2, a NAC transcription factor gene, regulates genes involved in secondary cell wall development in Arabidopsis fibres and increases fibre cell area in Eucalyptus (2011)

This study supports a function for SND2 in the regulation of cellulose and hemicellulose biosynthetic genes in addition of those involved in lignin polymerization and signalling. SND2 seems to occupy a subordinate but central tier in the secondary cell wall transcriptional network. Our results reveal phenotypic differences in the effect of SND2 overexpression between woody and herbaceous stems and emphasize the importance of expression thresholds in transcription factor studies.
Unsupervised learning in cross-corpus acoustic emotion recognition (2011)

One of the ever-present bottlenecks in Automatic Emotion Recognition is data sparseness. We therefore investigate the suitability of unsupervised learning in cross-corpus acoustic emotion recognition through a large-scale study with six commonly used databases, including acted and natural emotion speech, and covering a variety of application scenarios and acoustic conditions. We show that adding unlabeled emotional speech to agglomerated multi-corpus training sets can enhance recognition performance even in a challenging cross-corpus setting; furthermore, we show that the expected gain by adding unlabeled data on average is approximately half the one achieved by additional manually labeled data in leave-one-corpus-out validation.
High frequency magnetic field imaging by frequency modulated magnetic force microscopy (2010)

High frequency ac magnetic field from magnetic recording head was successfully imaged by using our newly developed frequency-modulated magnetic force microscopy (FM-MFM), which uses the frequency modulation of cantilever oscillation caused by applying ac magnetic field to a mechanically oscillated cantilever. The FM-MFM has been demonstrated and the experimental results show good agreement with our proposed models for FM-MFM. The amplitude and phase images of an ac magnetic field can be obtained separately by using the FM-MFM technique with a lock-in amplifier. By taking advantage of this technique, the present FM-MFM method opens a possibility to evaluate the magnetic field characteristics of magnetic recording head with high spatial resolution.
Über die Kondensation der Cyclohexanon‐(2)‐essigsäure‐(1) mit Tryptamin (1959)

Abstract Die Synthese der spirocyclischen Indolbase II wird beschrieben.
Nonradiative recombination via strongly localized defects in quantum wells (1994)

Using time-resolved photoluminescence, we have studied the nonradiative recombination of excess charge carriers in oxygen-implanted GaAs/${\mathrm{Al}}_{0.4}$${\mathrm{Ga}}_{0.6}$As single quantum wells. In order to reveal the recombination mechanism, the carrier lifetime is measured as a function of temperature and well width. We observe a decrease of the measured lifetime with increasing implantation dose and the nonradiative part of the recombination rate increases with increasing temperature. We find that the nonradiative recombination is thermally activated and the activation energies increase with decreasing well width. Under the assumption of strongly localized deep impurities we can explain this behavior with multiphonon capture processes and an analysis of the well-width dependence of the activation energies allows for the determination of the coupling strength for electron capture. In agreement with deep-level transient-spectroscopy (DLTS) measurements we determine a deep level 430 meV below the conduction band.
Preventing type 2 diabetes and cardiovascular disease in metabolic syndrome: the role of PPARα (2007)

The clustering of cardiovascular risk factors associated with the metabolic syndrome and type 2 diabetes suggests central mechanisms may exist that account for the presence of these abnormalities. Likewise, this clustering also suggests that key therapeutic targets may exist that could allow improvements in many of these parameters. Extensive data implicate peroxisome proliferator-activated receptor-alpha (PPARalpha) as an important transcriptional regulator of lipid metabolism, energy balance and inflammation. PPARalpha is also an established drug target. Experimental data show that activation of PPARalpha by agonists such as fenofibrate improves dyslipidaemia, increases cholesterol efflux and limits inflammation. All of these effects would also be predicted to decrease atherosclerotic risk. Evidence from surrogate markers in humans is also supportive of the concept that PPARalpha may act as a central target capable of influencing a variety of different pathways involved in lipid metabolism. Thus, fenofibrate offers the potential for inducing a co-ordinated PPARalpha response that may improve dyslipidaemia, repress inflammation and limit atherosclerosis in patients with the metabolic syndrome or type 2 diabetes.
Substrate Requirements of the Oxygen-sensing Asparaginyl Hydroxylase Factor-inhibiting Hypoxia-inducible Factor (2004)

The hypoxia-inducible factor alpha subunits 1 and 2 (HIF-1alpha and HIF-2alpha) are subjected to oxygen-dependent asparaginyl hydroxylation, a modification that represses the carboxyl-terminal transactivation domain (CAD) at normoxia by preventing recruitment of the p300/cAMP-response element-binding protein coactivators. This hydroxylation is performed by the novel asparaginyl hydroxylase, factor-inhibiting HIF-1' (FIH-1), of which HIF-1alpha and HIF-2alpha are the only reported substrates. Here we investigated the substrate requirements of FIH-1 by characterizing its subcellular localization and by examining amino acids within the HIF-1alpha substrate for their importance in recognition and catalysis by FIH-1. Using immunohistochemistry, we showed that both endogenous and transfected FIH-1 are primarily confined to the cytoplasm and remain there under normoxia and following treatment with the hypoxia mimetic, dipyridyl. Individual alanine mutations of seven conserved amino acids flanking the hydroxylated asparagine in HIF-1alpha revealed the importance of the valine (Val-802) adjacent to the targeted asparagine. The HIF-1alpha CAD V802A mutant exhibited a 4-fold lower V(max) in enzyme assays, whereas all other mutants were hydroxylated as efficiently as the wild type HIF-1alpha CAD. Furthermore, in cell-based assays the transcriptional activity of V802A was constitutive, suggesting negligible normoxic hydroxylation in HEK293T cells, whereas the wild type and other mutants were repressed under normoxia. Molecular modeling of the HIF-1alpha CAD V802A in complex with FIH-1 predicted an alteration in asparagine positioning compared with the wild type HIF-1alpha CAD, providing an explanation for the impaired catalysis observed and confirming the importance of Val-802 in asparaginyl hydroxylation by FIH-1.
Flexible circuits (1969)

Apart from their obvious advantage of flexibility, flexible printed circuits offer ease of installation, accuracy, repeatability and resistance to shock, high temperatures and chemical attack. The use of modern continuous processing techniques mean that their prices should continue to fall, making them more competitive with conventional cables in a wide range of applications, and increasing their use in new applications such as television scanning coils and computer memories.
Cellular organisation of the <i>Arabidopsis thaliana</i> root (1993)

The anatomy of the developing root of Arabidopsis is described using conventional histological techniques, scanning and transmission electron microscopy. The root meristem is derived from cells of the hypophysis and adjacent cells of the embryo proper. The postembryonic organization of the root is apparent in the mature embryo and is maintained in the growing primary root after germination. Cell number and location is relatively invariant in the primary root, with 8 cortical and endodermal cell files but more variable numbers of pericycle and epidermal cells. The organisation of cells in lateral roots is similar to that of the primary root but with more variability in the numbers of cell files in each layer. [3H]thymidine labeling of actively growing roots indicates that a quiescent centre of four central cells (derived from the hypophysis) is located between the root cap columella and the stele. This plate of four cells is surrounded by three groups of cells in, proximal, distal and lateral positions. The labeling patterns of these cells suggest that they are the initials for the files of cells that comprise the root. They give rise to four sets of cell files: the stele, the cortex and endodermis, the epidermis and lateral root-cap and the columella. A model of meristem activity is proposed based on these data. This description of Arabidopsis root structure underpins future work on the developmental genetics of root morphogenesis.
Ion pair formation of phosphorylated amino acids and lysine and arginine side chains: A theoretical study (1996)

Protein phosphorylation is one of the major signal transduction mechanisms for controlling and regulating intracellular processes. Phosphorylation of specific hydroxylated amino acid side chains (Ser, Thr, Tyr) by protein kinases can activate numerous enzymes; this effect can be reversed by the action of protein phosphatases. Here we report ab initio (HF/6-31G and Becke3LYP/6-31G) and semiempirical (PM3) molecular orbital calculations pertinent to the ion pair formation of the phosphorylated amino acids with the basic side chains of Lys and Arg. Methyl-, ethyl-, and phenylphosphate, as well as methylamine and methylguanidinium were used as model compounds for the phosphorylated and basic amino acids, respectively. Phosphorylated amino acids were calculated as mono- and divalent anions. Our results indicate that the PSer/PThr ion pair interaction energies are stronger than those with PTyr. Moreover, the interaction energies with the amino group of Lys are generally more favorable than with the guanidinium group of Arg. The Lys amino groups form stable bifurcated hydrogen bonded structures; while the Arg guanidinium group can form a bidentate hydrogen bonded structure. Reasonable values for the interaction free energies in aqueous solution were obtained for some complexes by the inclusion of a solvent reaction field in the computation (PM3-SM3).
Direct Enantioselective Organocatalytic Hydroxymethylation of Aldehydes Catalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether (2009)

The direct enantioselective hydroxymethylation of aldehydes utilizing alpha,alpha-diphenylprolinol trimethylsilyl ether as an organocatalyst is described. The intermediate alpha-substituted beta-hydroxyaldehydes were not isolated but converted to the more readily isolable derivatives. For example, the derived hydroxy acids were isolated in up to 94% yield with excellent enantioselectivity.
BlendCAC: A Smart Contract Enabled Decentralized Capability-Based Access Control Mechanism for IoT (2018)

While the Internet of Things (IoT) technology has been widely recognized as the essential part of Smart Cities, it also brings new challenges in terms of privacy and security. Access control (AC) is among the top security concerns, which is critical in resource and information protection over IoT devices. Traditional access control approaches, like Access Control Lists (ACL), Role-based Access Control (RBAC) and Attribute-based Access Control (ABAC), are not able to provide a scalable, manageable and efficient mechanism to meet the requirements of IoT systems. Another weakness in today's AC is the centralized authorization server, which can be the performance bottleneck or the single point of failure. Inspired by the smart contract on top of a blockchain protocol, this paper proposes BlendCAC, which is a decentralized, federated capability-based AC mechanism to enable an effective protection for devices, services and information in large scale IoT systems. A federated capability-based delegation model (FCDM) is introduced to support hierarchical and multi-hop delegation. The mechanism for delegate authorization and revocation is explored. A robust identity-based capability token management strategy is proposed, which takes advantage of the smart contract for registering, propagating and revocating of the access authorization. A proof-of-concept prototype has been implemented on both resources-constrained devices (i.e., Raspberry PI node) and more powerful computing devices (i.e., laptops), and tested on a local private blockchain network. The experimental results demonstrate the feasibility of the BlendCAC to offer a decentralized, scalable, lightweight and fine-grained AC solution for IoT systems.
Multibiometric systems (2004)

The latest research indicates using a combination of biometric avenues for human identification is more effective, and far more challenging.
An analytical back-gate bias effect model for ultrathin SOI CMOS devices (1993)

An analytical back-gate bias effect model for ultrathin SOI CMOS devices is presented. As verified by PISCES results, the analytical SOI CMOS back-gate bias effect model provides a much better accuracy in the integral potential distribution and the threshold voltage as the back-gate bias is changed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>