gebhart/patrepeval huggingface dataset:
On-Site Sensor Recalibration of a Spinning Multi-Beam LiDAR System Using Automatically-Detected Planar Targets (2012)

This paper presents a fully-automated method to establish a calibration dataset from on-site scans and recalibrate the intrinsic parameters of a spinning multi-beam 3-D scanner. The proposed method has been tested on a Velodyne HDL-64E S2 LiDAR system, which contains 64 rotating laser rangefinders. By time series analysis, we found that the collected range data have random measurement errors of around ±25 mm. In addition, the layered misalignment of scans among the rangefinders, which is identified as a systematic error, also increases the difficulty to accurately locate planar surfaces. We propose a temporal-spatial range data fusion algorithm, along with a robust RANSAC-based plane detection algorithm to address these issues. Furthermore, we formulate an alternative geometric interpretation of sensory data using linear parameters, which is advantageous for the calibration procedure. The linear representation allows the proposed method to be generalized to any LiDAR system that follows the rotating beam model. We also confirmed in this paper, that given effective calibration datasets, the pre-calibrated factory parameters can be further tuned to achieve significantly improved performance. After the optimization, the systematic error is noticeable lowered, and evaluation shows that the recalibrated parameters outperform the factory parameters with the RMS planar errors reduced by up to 49%.
Mechanisms of Foam Destruction by Oil-Based Antifoams (2004)

Oils and mixtures of oils with hydrophobic particles are widely used in various technologies and consumer products to control foaminess and foam stability. The aim of this review is to summarize our current understanding of the mechanisms of foam destruction by such substances, which are usually called antifoams or defoamers. The experimental results show that two types of antifoam can be distinguished (called for brevity "fast" and "slow") which differ in the modes of their action. Fast antifoams are able to rupture the foam films at the early stages of film thinning. As a result, fast antifoams destroy completely the foam in less than a minute, in a typical foam-stability test. Microscopic observations have shown that the fast antifoams rupture the foam films by the so-called "bridging" mechanisms, which involve the formation of oil bridges between the two surfaces of the foam film. The stability/instability of these oil bridges is explained by using the theory of capillarity. In contrast, the oily globules of the slow antifoams are unable to enter the surfaces of the foam films and are first expelled into the Plateau borders (PBs). Only after being compressed by the narrowing walls of the PBs (due to water drainage from the foam), are the globules of the slow antifoams able to enter the solution surface and to destroy the adjacent foam films. Typically, the process of foam destruction by slow antifoams requires much longer time, minutes or tens of minutes, and a residual foam of well-defined height is observed in the foam tests. The experiments show that there is no direct relation between the magnitudes of the entry, E, spreading, S, and bridging, B, coefficients, on one side, and the antifoam efficiency, on the other side. The only requirement for having active antifoam, with respect to the bridging mechanisms, is that B should be positive. On the other hand, the barrier preventing the emergence of pre-emulsified antifoam globules on the solution surface (so-called "entry barrier") is of crucial importance for the mode of foam destruction and for the antifoam efficiency. Measurements of the entry barrier with recently developed film trapping technique (FTT) showed that antifoams possessing low entry barriers act as fast antifoams, whereas high barriers correspond to slow or inactive antifoams, although E, S, and B coefficients could be strongly positive in the latter case. A good agreement between the magnitude of the entry barrier, measured by FTT, and the height of the residual foam, in the presence of slow antifoams, was experimentally established and theoretically explained. The importance of various factors, such as the size of antifoam globules, oil spreading, kinetics of surfactant adsorption, hydrophobicity of solid particles in mixed oil-solid antifoams, and the presence of amphiphilic additives (foam boosters), is discussed from the viewpoint of the mechanisms of antifoaming. The main experimental methods, used for studying the modes of antifoam action, are briefly described.
Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody (2013)

Cynomolgus monkeys dosed with a therapeutic monoclonal antibody (mAbY.1) at ≥ 50 mg/kg had unexpected acute thrombocytopenia (nadir ~3,000 platelets/µl), sometimes with decreases in red cell mass. Increased activated macrophages, mitotic figures, and erythrophagocytosis were observed in the spleen. Binding of mAbY.1 to cynomolgus peripheral blood cells could not be detected in vitro. mAbY.1 induced phagocytosis of platelets by peripheral blood monocytes from cynomolgus monkeys, but not from humans. mAbs sharing the same constant domain (Fc) sequences, but differing from mAbY.1 in their variable domains, bound competitively to and had similar biological activity against the intended target. None of these antibodies had hematologic liabilities in vitro or in vivo. Neither the F(ab')2 portion of mAbY.1 nor the F(ab')2 portion on an aglycosylated Fc (IgG1) framework caused phagocytosis of platelets in vitro. These data suggest that the hematologic effects of mAbY.1 in cynomolgus monkeys likely occurred through an off-target mechanism, shown to be driven by 1 to 3 amino acid differences in the light chain. The hematologic effects made mAbY.1 an unsuitable candidate for further development as a therapeutic agent. This example demonstrates that nonclinical safety studies may be essential for understanding off-target effects of mAbs prior to clinical trials.
Long-haul transmission of16×52.5 Gbits/s polarization-division- multiplexed OFDM enabled by MIMO processing (Invited) (2008)

<p><a href="http://jon.osa.org/virtual_issue.cfm?vid=54">Focus Issue on Orthogonal-Frequency-Division Multiplexed Communications Systems and Networks</a></p>We discuss the realization and performance of polarization-division-multiplexed orthogonal frequency division multiplexing (PDM-OFDM) for long-haul transmission systems. Polarization demultiplexing of the PDM signal at the receiver is realized by employing a multiple-input multiple-output (MIMO) detector. Using a recirculating loop a long-haul transmission experiment is reported of 52.5 Gbits/s PDM-OFDM (40 Gbits/s after coding) over 4160 km of standard single-mode fiber (SSMF). In this transmission experiment, 16 wavelength-division-multiplexed (WDM) channels are transmitted at 50 GHz channel spacing, and we show that MIMO processing in the receiver enables both polarization demultiplexing and a large PMD tolerance.
Maneschi, Andrea, Comparative Advantage in International Trade: A Historical Perspective (2000)

(2000). Maneschi, Andrea, Comparative Advantage in International Trade: A Historical Perspective. The International Trade Journal: Vol. 14, No. 3, pp. 315-320.
Herr Dulk kommt (1994)

Meine Erinnerungen an Verlagsvertreter reichen (und wie könnte es bei einem Buchhändlersohn anders sein?) in die Jugend, sogar in die Kindheit zurück. In unserem Elternhaus wurde immer über Bücher und Verlage und über Menschen, die mit Büchern zu tun hatten, gesprochen. Es gab keinen Graben zwischen Geschäft und privater Sphäre. Eins ging ins andere über, mit einer Selbstverständlichkeit, die heute erstaunen mag. Wir fanden nichts Befremdliches dabei.
Chemical Assay of Iron in Ovarian Cysts: A New Diagnostic Method to Evaluate Endometriotic Cysts (1998)

CA-125 is abundantly secreted from ovarian endometriotic cysts, but is not specific to endometriosis. In order to develop a new, more specific diagnostic marker for endometriosis, the iron concentrations in various ovarian cysts were assayed. The ovarian cysts were punctured and the contents aspirated laparoscopically, laparotomically, or transvaginally. The iron concentration in the ovarian cystic fluid was assayed using a spectrophotometer after protein precipitations and chromogen treatment. The iron concentrations in ovarian cysts were 69.5+/-10.4 micromol/l in serous cystadenomas, 73.5+/-29.3 in mucinous cystadenomas, 65.4+/-12.4 in dermoid cysts, and 92.5+/-18.2 micromol/l in adenocarcinomas. On the other hand, high iron concentrations were demonstrated in endometriotic cysts (1,749.6+/-41.5 micromol/l), a lutein cyst (1,393.8), hemorrhagic corpus luteum (1,957.5) and endometrioid adenocarcinomas (1,860.9+/-157.9 micromol/l). Cytological smear tests of the contents as well as histological examination allowed differential diagnosis between endometriosis and endometrioid adenocarcinoma. In conclusion, assay of the ovarian cystic iron concentration is a useful diagnostic tool for the evaluation of ovarian endometriotic cysts.
Cross-View People Tracking by Scene-Centered Spatio-Temporal Parsing (2017)

In this paper, we propose a Spatio-temporal Attributed Parse Graph (ST-APG) to integrate semantic attributes with trajectories for cross-view people tracking. Given videos from multiple cameras with overlapping field of view (FOV), our goal is to parse the videos and organize the trajectories of all targets into a scene-centered representation. We leverage rich semantic attributes of human, e.g., facing directions, postures and actions, to enhance cross-view tracklet associations, besides frequently used appearance and geometry features in the literature.In particular, the facing direction of a human in 3D, once detected, often coincides with his/her moving direction or trajectory. Similarly, the actions of humans, once recognized, provide strong cues for distinguishing one subject from the others. The inference is solved by iteratively grouping tracklets with cluster sampling and estimating people semantic attributes by dynamic programming.In experiments, we validate our method on one public dataset and create another new dataset that records people's daily life in public, e.g., food court, office reception and plaza, each of which includes 3-4 cameras. We evaluate the proposed method on these challenging videos and achieve promising multi-view tracking results.
A Fiber Optic PD Sensor Using a Balanced Sagnac Interferometer and an EDFA-Based DOP Tunable Fiber Ring Laser (2014)

A novel fiber-optic acoustic sensor using an erbium-doped fiber amplifier (EDFA)-based fiber ring laser and a balanced Sagnac interferometer for acoustic sensing of the partial discharge (PD) in power transformers is proposed and demonstrated. As a technical background, an experimental investigation on how the variations of the fiber birefringence affect the sensor performances was carried out, and the results are discussed. The operation principles are described, and the relevant formulas are derived. The analytical results show that an EDFA-based fiber ring laser operating in chaotic mode can provide a degree of polarization (DOP) tunable light beam for effectively suppressing polarization fading noises. The balanced Sagnac interferometer can eliminate command intensity noises and enhance the signal-to-noise ratio (SNR). Furthermore, it inherently operates at the quadrature point of the response curve without any active stabilizations. Several experiments are conducted for evaluating the performances of the sensor system, as well as for investigating the ability of the detection of high-frequency acoustic emission signals. The experimental results demonstrate that the DOP of the laser beam can be continuously tuned from 0.2% to 100%, and the power fluctuation in the whole DOP tuning range is less than 0.05 dBm. A high-frequency response up to 300 kHz is reached, and the high sensing sensitivity for detections of weak corona discharges, as well as partial discharges also is verified.
Conformational transitions in Pf3 and their implications for the structure and assembly of filamentous bacterial viruses. (1981)

Laser Raman and circular dichroism spectra of filamentous bacteriophage Pf3 show that its coat protein is predominantly alpha-helical, similar to the subunits of bacteriophages Pf1 and fd. Unlike Pf1 and fd, however, the subunits of Pf3 are converted to beta-sheet structures by raising the temperature, the transition temperature depending upon phage and NaCl concentrations. On cooling, the beta structure reverts to an alpha structure the same as or similar to the native structure. On further heating it converts irreversibly to a second alpha-helical form different from the original one. The spectra also show that aromatic amino acid residues of Pf3 undergo dramatic changes in molecular environment during the alpha leads to beta transition. Similar transitions are observed to take place in the filamentous bacteriophage Xf.
Methanol Improves Methane Uptake in Starved Methanotrophic Microorganisms (1998)

Methanotrophs in enrichment cultures grew and sustained atmospheric methane oxidation when supplied with methanol. If they were not supplied with methanol or formate, their atmospheric methane oxidation came to a halt, but it was restored within hours in response to methanol or formate. Indigenous forest soil methanotrophs were also dependent on a supply of methanol upon reduced methane access but only when exposed to a methane-free atmosphere. Their immediate response to each methanol addition, however, was to shut down the oxidation of atmospheric methane and to reactivate atmospheric methane oxidation as the methanol was depleted.
DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase (1999)

Mammalian DNA ligases are composed of a conserved catalytic domain flanked by unrelated sequences. At the C-terminal end of the catalytic domain, there is a 16-amino acid sequence, known as the conserved peptide, whose role in the ligation reaction is unknown. Here we show that conserved positively charged residues at the C-terminal end of this motif are required for enzyme-AMP formation. These residues probably interact with the triphosphate tail of ATP, positioning it for nucleophilic attack by the active site lysine. Amino acid residues within the sequence RFPR, which is invariant in the conserved peptide of mammalian DNA ligases, play critical roles in the subsequent nucleotidyl transfer reaction that produces the DNA-adenylate intermediate. DNA binding by the N-terminal zinc finger of DNA ligase III, which is homologous with the two zinc fingers of poly(ADP-ribose) polymerase, is not required for DNA ligase activity in vitro or in vivo. However, this zinc finger enables DNA ligase III to interact with and ligate nicked DNA at physiological salt concentrations. We suggest that in vivo the DNA ligase III zinc finger may displace poly(ADP-ribose) polymerase from DNA strand breaks, allowing repair to occur.
Indium-111-labeled human polymorphonuclear leukocytes: viability, random migration, chemotaxis, bacterial capacity, and ultrastructure. (1979)

Human polymorphonuclear leukocytes (PMNs) were labeled with indium-111 oxine in ethanol, and the effects of the labeling procedure, radioactivity, and concentrations of oxine and ethanol on PMN function and structure were studied in vitro. The standard labeling procedure did not alter the viability, random migration, chemotaxis, bactericidal capacity, or the ultrastructure of PMNs. Exposure to higher doses of radioactivity, or to higher concentrations of ethanol, had no appreciable effects on random migration and chemotaxis of PMNs. A dose-dependent reduction in their random migration and chemotaxis was observed when higher concentrations of oxine were used. These results indicate that In-111-labeled PMNs are structurally intact and have normal in vitro locomotion and bactericidal activity. Indium-111-labeled PMNs should be suitable for studying the kinetics and distribution of these cells in health and disease.
Second-order compensated bandgap reference with convex correction (2005)

A correction technique for second-order temperature variation of bandgap voltage references (BGR) is presented. It consists in adding a convex curve with a simple circuit to the standard bell curve of a first-order BGR. The temperature coefficient of the new BGR is as low as 1 ppm/°C.
BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo (2005)

Introducing mutations within the amyloid precursor protein (APP) that affect beta- and gamma-secretase cleavages results in amyloid plaque formation in vivo. However, the relationship between beta-amyloid deposition and the subcellular site of Abeta production is unknown. To determine the effect of increasing beta-secretase (BACE) activity on Abeta deposition, we generated transgenic mice overexpressing human BACE. Although modest overexpression enhanced amyloid deposition, high BACE overexpression inhibited amyloid formation despite increased beta-cleavage of APP. However, high BACE expression shifted the subcellular location of APP cleavage to the neuronal perikarya early in the secretory pathway. These results suggest that the production, clearance, and aggregation of Abeta peptides are highly dependent on the specific neuronal subcellular domain wherein Abeta is generated and highlight the importance of perikaryal versus axonal APP proteolysis in the development of Abeta amyloid pathology in Alzheimer's disease.
Novel interleaver based on modified Michelson interferometer with three-mirror Fabry-Perot interferometer and Gires-Tournois resonator (2002)

A novel Interleaver using a modified Michelson interferometer in which its reflecting mirrors are replaced by three-mirror Fabry-Perot interferometer and Gires-Tournois resonator respectively is presented. On basis of the theory of Michelson interference, a designing principle of the interleaver, which has square-like frequency response with zero ripple, wide flat-top, unity contrast, simple structure, and stable performance, is given. The device which possesses channel spacing of 50GHz, zero ripple, 0.5dB bandwidth more than O.27nm, and close channel isolation more than 73dB has been designed.
Validation of Control Software Specification Using Design Interests Extraction and Model Checking (2012)

<div class="section abstract"><div class="htmlview paragraph">Automotive control systems such as powertrain control interact with the open physical environment, and from this nature, expensive prototyping is indispensable to capture a deep understanding of the system requirements and to develop the corresponding control software. Model-based development (MBD) has been promoted to improve productivity by virtual prototyping. Even with MBD, systematic validation of the software specification remains as a major challenge and it still depends heavily on individual engineers' skill and knowledge. Though the introduction of graphical software modeling improved the situation, it requires much time to identify the primal functions, so-called “design interests”, from a large complex model where irrelevant components are mixed with, and to validate it properly. In addition, since software models have to coexist with legacy assets during the transition to MBD, the difficulty mentioned above should be overcome in terms of not only models, but also legacy C codes. As a remedy to this problem, we propose an approach based on design interests extraction from software model and/or legacy code. Design interests are mechanically extracted in the form of functional models and model checking is applied to exercise them. Currently, with our first tool implementation, a kind of dataflow graph is extracted from C codes as a functional model, and model checking is applied to prove specified properties on the dataflow graph and to generate execution traces which stimulate the specific parts of the design in a pinpoint manner. Such conditions are derived from the functional model.</div></div>
Depsides isolated from the Sri Lankan lichen<i>Parmotrema</i>sp. exhibit selective Plk1 inhibitory activity (2011)

These data suggest that the depsides 1-3 may serve as core structures that can be further explored as potential inhibitors of Plk1 and other kinases.
Feature extraction with a multiscale modulation analysis for robust automatic speech recognition (2013)

In this work we present a new feature extraction method that is robust against the effects of varying vocal tract lengths. The principle of the method is based on invariant integration and makes use of a modulation filtering approach, similar to the recently proposed scattering transform. In particular, we show how the transform can be used to obtain features that are robust against variations of the vocal tract length. Phoneme recognition experiments show a clearly increased robustness in case of mismatching average vocal tract lengths.
Neonatal herpes simplex virus infections (1994)

Neonatal herpes simplex virus infections cause significant morbidity and mortality among infected babies, despite the availability of antiviral therapy. These infections manifest in one of three forms: skin, eye, and mouth involvement; encephalitis; or disseminated infection. The latter two forms of disease account for more than 50% of babies with neonatal herpes and are associated with mortality and severe morbidity rates that exceed 75% in infected children. Thus future therapeutic efforts must be directed toward improved disease outcome. One such effort is the evaluation of immunoglobulin products (humanized monoclonal antibodies, human monoclonal antibodies and hyperimmune globulin) as part of a concomitant therapeutic regimen for babies with encephalitis and disseminated infection. The logic for such an approach becomes especially apparent for babies with disseminated disease because little transplacental maternal antibody is received at the time of birth. Thus concomitant administration of antiviral therapy with antibody may improve disease outcome.
Effect of sol aging time on the anti-reflective properties of silica coatings templated with phosphoric acid (2016)

Silica anti-reflective coatings have been prepared by a sol–gel dip-coating process using the sol containing phosphoric acid as a pore-forming template. The effect of the aging time of the sol on the anti-reflective properties has been investigated. The surface topography of the silica AR coatings has been characterized. With increasing sol aging time, more over-sized pores larger than 100 nm are formed in the silica coatings. These could act as scattering centers, scattering visible light and thereby lowering transmittance. The optimal aging time was identified as 1 day, and the corresponding silica coatings showed a maximum transmittance of 99.2%, representing an 8% increase compared to the bare glass substrate.
Multiple hole ejector performance with short wide angle diffusers (1994)

The performance of a thrust augmenting ejector with multiple nozzle outlets for the primary jets is discussed. The addition of short diffusers at the end of the ejector and the utilization of the primary jets for boundarylayer control have resulted in a new high level of performance with a force augmentation greater than two. Diffusers having ejector length-to-mixing chamber diameter ratios of approximately (1.5-3.7) with diffuser half angles from (4.6-11 deg), and mixing chamber inlet area-to-primary nozzle area ratios of 36:1 and 72:1, were designed and tested. Additionally, a theoretical analysis of ejector performance was formulated. Comparisons between predicted and experimental performances as a function of the primary nozzle pressure ratio are discussed. Incomplete mixing and diffuser losses are measured and accounted for in a compressible control volume analysis. The data include selected experimental exit velocity profiles demonstrating the degradation of force augmentation at the higher pressure ratios.