gebhart/patrepeval huggingface dataset:
Pax2 mutant mice display increased number and size of islets of Langerhans but no change in insulin and glucagon content (2004)

Pax2 is a paired box transcription factor expressed in a spatially and temporally restricted manner and its absence results in major developmental defects of the central nervous system, eyes, ears and urogenital system. We recently reported that Pax2 is expressed in pancreatic endocrine cell lines and adult islets of Langerhans and activates glucagon gene expression. We have shown here that the Pax2 gene is expressed during pancreas development as early as embryonic day 10.5. Its absence, as assessed in Pax2(1Neu) mutant mice, results in a two- to threefold increase in the average pancreas volume occupied by the islets in both heterozygous and homozygous mutant mice with a gene-dependent dosage effect. This increase, which is due to a change in the number of islets per unit pancreas volume and in the size of individual islets, is not accompanied by significant modification in the insulin or glucagon content of the pancreas, indicating that the content of these hormones per cell is decreased. We have concluded that Pax2 may be implicated in the prenatal determination of the relative proportion of the endocrine and exocrine tissues of the pancreas.
Aeroacoustic flow sensor (1991)

A theoretical analysis of standing waves in a pipe with flow was conducted aimed toward the development of a flowmeter based on a measurement of phase difference between two points on the circumference of a pipe separated axially by an integral multiple of half sound wavelength. Effects of nonzero Mach number, variable ratios of upstream and downstream running waves, choice of location of the sensing pressure taps, and the incorrect spacings were examined numerically. Calculations were also made for steam flow where the maximum Mach number is much smaller than in cold air flows. For an industrial application where steam flow velocities are below 50 m/s, a very accurate sensor is shown to be possible. Experimental data were obtained by using an active aeroacoustic source over the range of 50 m/s to zero in an air flow. Experimental phase plots obtained from several coast-down tests have been compared with analytical results. The agreement with theory is excellent when the spacings are near Nλ/2 and the sensing locations are near the pressure antinodes. Otherwise, some zero shifts are introduced. Theory predicts that for steam flow much better results can be expected because the maximum Mach number is much smaller. Effects due to the (1−M2) factor would be imperceptible for steam flow.
Carbon-13 Nuclear Magnetic Resonance Study of the Rapid Steam Hydrolysis of Read Oak (1984)

The extent of hydrolysis of aryl-alkyl ether linkages by rapid steam hydrolysis (RASH) of red oak is characterized by 13C NMR using cross polarization and magic-angle spinning. The NMR spectra of the RASH products show evidence of the removal of hemicelluloses. The NMR spectrum of the solid isolated from the steam condensate is compared with the spectrum of HCl lignin prepared from red oak. The 13C spectrum of steam condensate lignin shows evidence of extensive depolymerization.
Analysis of a Global Online Debate and the Development of an Interaction Analysis Model for Examining Social Construction of Knowledge in Computer Conferencing (1997)

This study attempts to find appropriate interaction analysis/content analysis techniques that assist in examining the negotiation of meaning and co-construction of knowledge in collaborative learning environments facilitated by computer conferencing. The authors review strengths and shortcomings of existing interaction analysis techniques and propose a new model based on grounded theory building for analyzing the quality of CMC interactions and learning experiences. This new Interaction Analysis Model for Examining Social Construction of Knowledge in Computer Conferencing was developed after proposing a new definition of “interaction” for the CMC context and after analyzing interactions that occurred in a Global Online Debate. The application of the new model for analysis of collaborative construction of knowledge in the online debate and in a subsequent computer conference are discussed and future research suggested.
Similarities and differences between fish oligodendrocytes and schwann cells in vitro (1994)

In light of the striking differences between oligodendrocytes of the optic nerve/tract of adult goldfish and their mammalian counterparts, a further characterization of goldfish oligodendrocytes was performed. A comparison with Schwann cells was included because fish optic nerve/tract-derived oligodendrocytes bear remarkable similarities to this type of glial cell. Fish optic nerve/tract-derived oligodendrocytes that had differentiated into 04 and 6D2-positive cells and thus expressed early myelin marker molecules were found to incorporate BrdU and to divide in vitro over a period of weeks. For the induction of more advanced markers of myelinogenesis such as the CNS-specific myelin protein 36K, oligodendrocytes required extensive contact with axons. Other agents, such as fetal calf or carp serum, substrate components, or forscolin failed, however, to induce 36K expression. 04/6D2-positive oligodendrocytes could be distinguished from fish 6D2-positive Schwann cells derived from cranial nerves by their antigenic phenotype: Schwann cells but not oligodendrocytes exhibited the low affinity NGF receptor. While both cell types carry the cell adhesion molecules NCAM, E 587 antigen, and the L2/HNK-1 epitope, only Schwann cells possess a further adhesion molecule, Neurolin.
Optimally sparse representation in general (nonorthogonal) dictionaries via ℓ <sup>1</sup> minimization (2003)

Given a dictionary D = {d(k)} of vectors d(k), we seek to represent a signal S as a linear combination S = summation operator(k) gamma(k)d(k), with scalar coefficients gamma(k). In particular, we aim for the sparsest representation possible. In general, this requires a combinatorial optimization process. Previous work considered the special case where D is an overcomplete system consisting of exactly two orthobases and has shown that, under a condition of mutual incoherence of the two bases, and assuming that S has a sufficiently sparse representation, this representation is unique and can be found by solving a convex optimization problem: specifically, minimizing the l(1) norm of the coefficients gamma. In this article, we obtain parallel results in a more general setting, where the dictionary D can arise from two or several bases, frames, or even less structured systems. We sketch three applications: separating linear features from planar ones in 3D data, noncooperative multiuser encoding, and identification of over-complete independent component models.
An experimental study of jejunal pouch replacements following total gastrectomy. (2002)

The present study showed no nutritional benefits of an iso- as well as an anti-peristaltic pouch replacement.
Taking Health Status Into Account When Setting Capitation Rates (1996)

<h3>Objective.</h3> —To compare performance of different health status measures for risk-adjusting capitation rates. <h3>Design.</h3> —Cross-sectional study. Health status measures derived from 1 year were used to predict resources for that year and the next. <h3>Setting.</h3> —Group-network health maintenance organization in Minnesota. <h3>Participants.</h3> —Sample of 18- to 64-year-old (n=3825) and elderly (aged ≥65 years; n=1955) members enrolled in a network-model health maintenance organization in Minnesota. <h3>Main Outcome Measures.</h3> —Total expenditures in the year concurrent with the health status survey (July 1991 through June 1992) and total expenditures in the year following the survey (July 1992 through June 1993). <h3>Results.</h3> —Capitation adjustment based on demographic measures performed least well. Both self-reported health status measures and diagnoses predicted future expenditures twice as well as demographics. When predicting costs for groups of patients rather than individuals, the demographic model worked well for average groups but tended to overpredict healthier groups and underpredict sicker groups. Ambulatory Care Groups based on diagnoses performed better than self-reported health status both in the retrospective models and across healthier and sicker groups. <h3>Conclustion.</h3> —Without risk adjustment, capitation rates are likely to overpay or underpay physicians for certain patient groups. It is possible to improve prediction using health status measures for risk adjustment. When selection bias is suspected and administrative data are available, we recommend a risk-adjustment method based on diagnostic information. If diagnostic data are not available, we recommend a system based on simple self-reported measures, such as chronic conditions, rather than complex functional status measures.
Cost estimation for rapid manufacturing - laser sintering production for low to medium volumes (2006)

Rapid manufacturing (RM) is a modern production method based on layer by layer manufacturing directly from a three-dimensional computer-aided design model. The lack of tooling makes RM economically suitable for low and medium production volumes. A comparison with traditional manufacturing processes is important; in particular, cost comparison. Cost is usually the key point for decision making, with break-even points for different manufacturing technologies being the dominant information for decision makers. Cost models used for traditional production methodologies focus on material and labour costs, while modern automated manufacturing processes need cost models that are able to consider the high impact of investments and overheads. Previous work on laser sintering costing was developed in 2003. This current work presents advances and discussions on the limits of the previous work through direct comparison. A new cost model for laser sintering is then proposed. The model leads to graph profiles that are typical for layer-manufacturing processes. The evolution of cost models and the indirect cost significance in modern costing representation is shown finally.
The design of PDA application schemes for wireless communication services (2002)

Current researches on PDA are emphasizing the technical issues such as the hardware organization or language for remote communication. However, the details of the wireless PDA services are yet to be defined. We need to know what kind of services can be conducted and what data should be transmitted in what manner in order to complete the service. This research provides a practical application layer design which examines the possible categories of wireless PDA services and, for each category, the necessary data formats designed for conducting the service. The aim is to figure out an organized and feasible application scheme which, when being employed, makes the wireless PDA services viable.
Alcohol Dehydrogenase from Lactobacillus brevis: A Versatile Robust Catalyst for Enantioselective Transformations (2011)

The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regioand enantioselectivity. In this critical review, we have gathered the information available on the substrate scope as well as the applications reported. Quantitative information such as productivity per catalyst, space-time yield (STY), cofactor utilisation, and stability are derived to allow comparison and assessment of practical value.
Total Knee Arthroplasty Using the Kinematic Rotating Hinge Prosthesis (1989)

Patients receiving a Kinematic Rotating Hinge total knee prosthesis with a 25-month minimum follow up were reviewed. A total of 46 patients and 54 knees were included in the study. A detailed clinical assessment was available on 38 knees. Twenty of these knees had primary arthroplasties performed with the Kinematic Rotating Hinge prosthesis and 18 knees had revision arthroplasty. Ninety-five percent of primary knees and 83% of revision knees caused no or mild pain postoperatively. Using the Brigham and Women's Hospital and Harvard Medical School knee rating system, 80% of primary knees and 61% of revision knees were rated as good to excellent. Using the criteria defined in this article, 90% of primary knees and 83% of revision knees were labeled as having a satisfactory result. Forty-five percent of primary components and 52% of revision components demonstrated lucent lines on radiographic review. Seven percent of primary knees and 20% of revision knees showed evidence of aseptic lucency progression in one or more zones. No radiographic evidence of aseptic loosening was noted in this review. Documented sepsis occurred in one primary knee and two revision knees. Patellar instability occurred in 21% of primary knees and 36% of revision knees, representing the major complication. The Kinematic Rotating Hinge prosthesis is intended for use in arthroplasty cases where there is functional absence of collateral ligament stability. This review suggests that a high percentage of satisfactory clinical results can be achieved with this prosthesis with long-term radiographic stability.
Phoenix-based clone detection using suffix trees (2006)

A code clone represents a sequence of statements that are duplicated in multiple locations of a program. Clones often arise in source code as a result of multiple cut/paste operations on the source, or due to the emergence of crosscutting concerns. Programs containing code clones can manifest problems during the maintenance phase. When a fault is found or an update is needed on the original copy of a code section, all similar clones must also be found so that they can be fixed or updated accordingly. The ability to detect clones becomes a necessity when performing maintenance tasks. However, if done manually, clone detection can be a slow and tedious activity that is also error prone. A tool that can automatically detect clones offers a significant advantage during software evolution. With such an automated detection tool, clones can be found and updated in less time. Moreover, restructuring or refactoring of these clones can yield better performance and modularity in the program.This paper describes an investigation into an automatic clone detection technique developed as a plug-in for Microsoft's new Phoenix framework. Our investigation finds function-level clones in a program using abstract syntax trees (ASTs) and suffix trees. An AST provides the structural representation of the code after the lexical analysis process. The AST nodes are used to generate a suffix tree, which allows analysis on the nodes to be performed rapidly. We use the same methods that have been successfully applied to find duplicate sections in biological sequences to search for matches on the suffix tree that is generated, which in turn reveal matches in the code.
Evaluation of SystemC Modelling of Reconfigurable Embedded Systems (2005)

This paper evaluates the use of pin and cycle accurate SystemC models for embedded system design exploration and early software development. The target system is the MicroBlaze VanillaNet Platform running MicroBlaze uClinux operating system. The paper compares register transfer level (RTL) hardware description language (HDL) simulation speed to the simulation speed of several different SystemC models. It is shown that simulation speed of pin and cycle accurate models can go up to 150 kHz, compared to the 100 Hz range of HDL simulation. Furthermore, utilising techniques that temporarily compromise cycle accuracy, effective simulation speed of up to 500 kHz can be obtained.
Totally Recalling Arnold: Sex and Violence in the New Bad Future (1990)

Research Article| October 01 1990 Totally Recalling Arnold: Sex and Violence in the New Bad Future Fred Glass Fred Glass Search for other works by this author on: This Site PubMed Google Scholar Film Quarterly (1990) 44 (1): 2–13. https://doi.org/10.2307/1212694 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Fred Glass; Totally Recalling Arnold: Sex and Violence in the New Bad Future. Film Quarterly 1 October 1990; 44 (1): 2–13. doi: https://doi.org/10.2307/1212694 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentFilm Quarterly Search This content is only available via PDF. Copyright 1990 The Regents of the University of California Article PDF first page preview Close Modal You do not currently have access to this content.
Identification of non-functional allelic variant of CYP1A2 in dogs (2004)

Our results indicate that more than 10% of the dogs studied were CYP1A2-null. Because CYP1A2-null phenotype in dogs affects the results of pharmacokinetic, toxicological and pharmacological studies of drug candidates, these findings are important in the pharmaceutical and the veterinary fields.
A Compact and Low-Profile Tunable Loop Antenna Integrated With Inductors (2008)

We present a frequency-tunable, compact loop antenna which consists of a transmission line on a ground plane, two shorting posts, and two inductors which are serially connected between the posts and the edge of the transmission line. By properly choosing the inductance of the inductors, the operating frequency of the antenna can be controlled without seriously sacrificing fractional bandwidth. To demonstrate the operating mechanism, the equivalent circuit of this antenna is included. The characteristics of the antenna with various inductors integrated are also investigated. Fabricated antennas show that the operating frequency can be shifted from 2.07 GHz to 1.2 GHz using off-the-shelf inductors. Using two 33-nH inductors achieves an antenna with an electrical size as small as 0.118lambda times 0.013lambda times 0.047lambda. The validity of this antenna is demonstrated by experimental results.
Inclusion Body Hepatitis in Young Broiler Breeders Associated with a Serotype 2 Adenovirus in Ontario, Canada (2005)

In July 2001 in southwestern Ontario, a young broiler breeder pullet flock experienced 2.1% mortality from 10 to 14 d of age. Mortality prior to and after this period was normal. Clinical signs included depression, lateral recumbency, and death with feed present in the crop. Necropsy lesions included friable, pale yellow-white livers scattered with hemorrhages. Histological examination revealed necrotizing hepatitis with large basophilic intranuclear inclusion bodies in the hepatocytes compatible with inclusion body hepatitis (IBH). An adenovirus from livers was isolated in chicken hepatoma cells. Virus neutralization and DNA analysis based on restriction fragment length polymorphism performed on this isolate were consistent with group I fowl adenovirus serotype 2. The origin of the adenovirus involved in this outbreak of IBH could not be established with certainty.
31P NMR studies of intracellular free Mg2+ in intact frog skeletal muscle. (1980)

The separation between the aP and PP resonances in the NMR spectrum of intracellular ATP may be used to measure the fraction of total ATP that is complexed to M&+ and, thereby, to estimate the level of free M&+ i n intact cells (Gupta, R.
MFM quantification of magnetic fields generated by ultra-small single pole perpendicular heads (1998)

The perpendicular fields emanating from an ultra small perpendicular single pole heads have been quantified using a new MFM field mapping technique. This technique utilizes two MFM tips with different field sensitivities which have been focused ion beam etched to identical geometries. This technique has been used to quantify the perpendicular fields around a 100/spl times/200 nm pole, also fabricated with focused ion beam etching.
T2S-Tensor: Productively Generating High-Performance Spatial Hardware for Dense Tensor Computations (2019)

We present a language and compilation framework for productively generating high-performance systolic arrays for dense tensor kernels on spatial architectures, including FPGAs and CGRAs. It decouples a functional specification from a spatial mapping, allowing programmers to quickly explore various spatial optimizations for the same function. The actual implementation of these optimizations is left to a compiler. Thus, productivity and performance are achieved at the same time. We used this framework to implement several important dense tensor kernels. We implemented dense matrix multiply for an Arria-10 FPGA and a research CGRA, achieving 88% and 92% of the performance of manually written, and highly optimized expert (ninja") implementations in just 3% of their engineering time. Three other tensor kernels, including MTTKRP, TTM and TTMc, were also implemented with high performance and low design effort, and for the first time on spatial architectures."
Synthetic Control of Structural Order in <i>N</i>-Alkylthieno[3,4-<i>c</i>]pyrrole-4,6-dione-Based Polymers for Efficient Solar Cells (2010)

The correlation between the nature of alkyl substituents on N-alkylthieno[3,4-c]pyrrole-4,6-dione (TPD)-based polymers and solar cell device performance has been investigated. After adjusting device parameters, these TPD-based polymers used with PC(61)BM provided photovoltaic responses ranging from 4.0% to 6.8%, depending on the size and shape of the alkyl solubilizing groups. Further, we have correlated the effect of the alkyl groups on the structural order and orientation of the polymer backbone using grazing incidence X-ray scattering analysis, and we have demonstrated how fine-tuning of these parameters can improve the power conversion efficiency.
Remote Sensing for Seismic Hazard Assessment of a Proposed Nuclear Power Station, North Wales, UK (1991)

During the seismic hazard assessment for a proposed nuclear power station in North Wales, UK, a remote sensing study was carried out in conjunction with other, wide-ranging geological investigations. The study used Landsat Thematic Mapper (TM) and Seasat SAR imagery. Image processing and interpretation of the TM data were iterative; the later iterations being designed to answer specific questions raised by the geological studies and t initial remote sensing interpretations.