gebhart/patrepeval huggingface dataset:
Synthesis of 3-Hydroxy-2-pyridinone Derivatives of 4-<i>tert</i>-Butylcalix[4]arenes:  A New Class of Selective Extractants of Actinide(IV) Ions (1999)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSynthesis of 3-Hydroxy-2-pyridinone Derivatives of 4-tert-Butylcalix[4]arenes: A New Class of Selective Extractants of Actinide(IV) IonsTimothy N. Lambert, Lakkaraju Dasaradhi, Vincent J. Huber, and Aravamudan S. GopalanView Author Information Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003-8001 Cite this: J. Org. Chem. 1999, 64, 16, 6097–6101Publication Date (Web):July 16, 1999Publication History Received4 March 1999Published online16 July 1999Published inissue 1 August 1999https://pubs.acs.org/doi/10.1021/jo990387shttps://doi.org/10.1021/jo990387sbrief-reportACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views526Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Actinides,Alcohols,Extraction,Ions,Ligands Get e-Alerts
2nd order adiabatic computation with 2N-2P and 2N-2N2P logic circuits (1995)

Recent advances in compact, practical adiabatic computing circuits which demonstrate signicant energy savings have renewed interest in using such techniques in lowpower systems. Several recently introduced circuits for adiabatic computing make use of diodes in a way which reduces switching energy from O(CVdd 2 ) in the nonadiabatic (ie: standard CMOS) case, to O(CV ddV t). These circuits provide an energy savings of at most one order of V dd=V t. This paper introduces a new class of adiabatic computing circuits which oer several advantages over existing approaches, the primary one being that, because no diodes are used, switching energy can be reduced to an energy oor of O(CVt 2 ). These second order adiabatic computing circuits provide an energy savings of as much a s O ( V dd=V t 2 ) o v er conventional CMOS. Additional advantages of the proposed circuits include the fact that, in comparison to most compact adiabatic circuits which h a v e oating output levels over the entire data valid time, these new circuits have nonoating output levels over most of the data valid time. This is important for restoring logic levels and minimizing problems with crosstalk. The proposed circuits have been simulated and demonstrate adiabatic power savings compared to standard CMOS circuits over an operating frequency range from 1MHz to 100MHz of as much a s a factor of 3. One circuit topology has been fabricated and tested and operates properly at up to 100MHz, the maximum speed which could be tested. Power measurements on the functioning circuit are in progress and preliminary results demonstrate adiabatic power-vs-frequency behavior. These second order adiabatic computing circuits provide an attractive alternative t o a c hieve adiabatic power savings without suering from many o f t h e limitations of alternative approaches and without costing much more either in terms of complexity or size.
DRACO--A THREE-DIMENSIONAL FEW-GROUP DEPLETION CODE FOR THE IBM-704 (1958)

A three-dimensional few-group depletion code prograrnmed for the IBM-704 is presented, The code, called DRACO, is used in studying the neutron flux, the power level, and the related buildup and depletion of materials at different stages in a reactor lifetime. The three sections of the code are described, and the background documents are referenced. (auth)
A New Calibration Method of the Projector in Structured Light Measurement Technology (2015)

The calibration of the projector is necessary in the structured light measurement system with only single projector and single camera. A new calibration method of the projector with a checkerboard calibration target and a specific projecting grid pattern is proposed. The method is divided into the following steps. First, during the calibrating process, at each position of the target, one photo is captured for the checkerboard target, and another is taken with the projector projecting the specific grid pattern on the target. Second, the camera is calibrated by Zhang Z's method using the captured photos of checkerboard target. Third, image binarization, skeletonization, Hough transform and corner detection are used to obtain the pixel coordinates of feature points in the photos of grid pattern. Further, the 3D world coordinates of feature points can be calculated by the pinhole imaging model based on results acquired by Step 2 and Step 3. Since the coordinates of the feature points in the pattern are previously configured, the parameters of projector are finally calculated via the 3D world and configured pixel coordinates of the feature points. The calibration device is easy to setup and the calibrating speed is fast. Experimental results prove the effectiveness and accuracy of the method.
Brain‐derived neurotrophic factor gene therapy prevents spiral ganglion degeneration after hair cell loss (1998)

Destruction of auditory hair cells results in the secondary degeneration of auditory neurons. This is because of the loss of neurotrophic factor support from the auditory hair cells, namely neurotrophin 3, which is normally produced by the inner hair cells. Both in vitro and in vivo studies have shown that delivery of either neurotrophin 3 or brain-derived neurotrophic factor to these neurons can replace the trophic support supplied by the hair cells and prevent their degeneration. To prevent the degeneration of auditory neurons that occurs after neomycin destruction of the auditory hair cells we used a replication defective herpes simplex-1 vector (HSVbdnflac) to transfect the gene for brain-derived neurotrophic factor into the damaged spiral ganglion. Four weeks after the HSVbdnflac therapy we were able to detect stable functional production of brain-derived neurotrophic factor that supported the survival of auditory neurons and prevented the loss of these neurons because of trophic factor deprivation-induced apoptosis.
Cavernosography in conjunction with artificial erection for evaluation of venous leakage in impotent men. (1986)

Twenty men with incomplete penile erection or inability to maintain an erection were evaluated to determine if venous leakage was a cause. Cavernosography was performed in conjunction with artificial erection induced by infusion of saline into the corpus cavernosa. Thirteen patients requiring higher than normal rates of saline infusion to achieve or maintain erection showed filling of superficial veins in the flaccid state as well as during erection. In five of the seven patients with normal saline requirements there was no filling of superficial veins, and two showed filling in the flaccid state only. Of the thirteen patients whose conditions were diagnosed as venous leakage, seven underwent surgical ligation of superficial veins and deep penile vein arterialization by a saphenous vein bypass graft between the superficial femoral artery and deep penile vein. All these patients had reduced saline requirements postoperatively. When cavernosography is performed in the flaccid state only, filling of superficial veins can occur normally; therefore, these studies should be performed with artificial erection.
Effects of 3' end deletions from the Vibrio harveyi luxB gene on luciferase subunit folding and enzyme assembly: generation of temperature-sensitive polypeptide folding mutants (1988)

Ten recombinant plasmids have been constructed by deletion of specific regions from the plasmid pTB7 that carries the luxA and luxB genes, encoding the alpha and beta subunits of luciferase from Vibrio harveyi, such that luciferases with normal alpha subunits and variant beta subunits were produced in Escherichia coli cells carrying the recombinant plasmids. The original plasmid, which conferred bioluminescence (upon addition of exogenous aldehyde substrate) on E. coli carrying it, was constructed by insertion of a 4.0-kb HindIII fragment of V. harveyi DNA into the HindIII site of plasmid pBR322 [Baldwin, T.O., Berends, T., Bunch, T. A., Holzman, T. F., Rausch, S. K., Shamansky, L., Treat, M. L., & Ziegler, M. M. (1984) Biochemistry 23, 3663-3667]. Deletion mutants in the 3' region of luxB were divided into three groups: (A) those with deletions in the 3' untranslated region that left the coding sequences intact, (B) those that left the 3' untranslated sequences intact but deleted short stretches of the 3' coding region of the beta subunit, and (C) those for which the 3' deletions extended from the untranslated region into the coding sequences. Analysis of the expression of luciferase from these variant plasmids has demonstrated two points concerning the synthesis of luciferase subunits and the assembly of those subunits into active luciferase in E. coli. First, deletion of DNA sequences 3' to the translational open reading frame of the beta subunit that contain a potential stem and loop structure resulted in dramatic reduction in the level of accumulation of active luciferase in cells carrying the variant plasmids, even though the luxAB coding regions remained intact.
Synthesis of Organoboron π-Conjugated Polymers by Hydroboration Polymerization between Heteroaromatic Diynes and Mesitylborane and Their Light Emitting Properties (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTSynthesis of Organoboron π-Conjugated Polymers by Hydroboration Polymerization between Heteroaromatic Diynes and Mesitylborane and Their Light Emitting PropertiesNoriyoshi Matsumi, Mamoru Miyata, and Yoshiki ChujoView Author Information Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan Cite this: Macromolecules 1999, 32, 13, 4467–4469Publication Date (Web):June 9, 1999Publication History Received18 May 1998Revised29 April 1999Published online9 June 1999Published inissue 1 June 1999https://pubs.acs.org/doi/10.1021/ma980785hhttps://doi.org/10.1021/ma980785hrapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views701Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Atmospheric chemistry,Boron,Conjugated polymers,Polymerization,Polymers Get e-Alerts
Surgical Guides (Patient-Specific Instruments) for Pediatric Tibial Bone Sarcoma Resection and Allograft Reconstruction (2013)

To achieve local control of malignant pediatric bone tumors and to provide satisfactory oncological results, adequate resection margins are mandatory. The local recurrence rate is directly related to inappropriate excision margins. The present study describes a method for decreasing the resection margin width and ensuring that the margins are adequate. This method was developed in the tibia, which is a common site for the most frequent primary bone sarcomas in children. Magnetic resonance imaging (MRI) and computerized tomography (CT) were used for preoperative planning to define the cutting planes for the tumors: each tumor was segmented on MRI, and the volume of the tumor was coregistered with CT. After preoperative planning, a surgical guide (patient-specific instrument) that was fitted to a unique position on the tibia was manufactured by rapid prototyping. A second instrument was manufactured to adjust the bone allograft to fit the resection gap accurately. Pathologic evaluation of the resected specimens showed tumor-free resection margins in all four cases. The technologies described in this paper may improve the surgical accuracy and patient safety in surgical oncology. In addition, these techniques may decrease operating time and allow for reconstruction with a well-matched allograft to obtain stable osteosynthesis.
Analysis of Borrelia burgdorferi membrane architecture by freeze-fracture electron microscopy (1994)

Freeze-fracture electron microscopy was used to investigate the membrane architectures of high-passage Borrelia burgdorferi B31 and low- and high-passage isolates of B. burgdorferi N40. In all three organisms, fractures occurred almost exclusively through the outer membrane (OM), and the large majority of intramembranous particles were distributed randomly throughout the concave OM leaflet. The density of intramembranous particles in the concave OM leaflet of the high-passage N40 isolate was significantly greater than that in the corresponding leaflet of the low-passage N40 isolate. Also noted in the OMs of all three organisms were unusual structures, designated linear bodies, which typically were more or less perpendicular to the axis of the bacterium. A comparison of freeze-fractured B. burgdorferi and Treponema pallidum, the syphilis spirochete, revealed that the OM architectures of these two pathogens differed markedly. All large membrane blebs appeared to be bounded by a membrane identical to the OM of B. burgdorferi whole cells; in some blebs, the fracture plane also revealed a second bilayer closely resembling the B. burgdorferi cytoplasmic membrane. Aggregation of the lipoprotein immunogens outer surface protein A (OspA) and OspB on the bacterial surface by incubation of B. burgdorferi B31 with specific polyclonal antisera did not affect the distribution of OM particles, supporting the contention that lipoproteins do not form particles in freeze-fractured OMs. The expression of poorly immunogenic, surface-exposed proteins as virulence determinants may be part of the parasitic strategy used by B. burgdorferi to establish and maintain chronic infection in Lyme disease.
Comprehensive studies of response characteristics of organic photodetectors based on rubrene and C-60 (2014)

We studied the transient response characteristics of organic photodetectors composing of high mobility materials of rubrene and C-60, respectively, as donor and acceptor. It was found that the response speed was limited by the delay time of both exciton diffusion and transit, and an anomalous phenomenon that the bandwidth decreases as the reverse bias increases was found for the first time. The investigation of frequency dependence at different device structures and light excitations demonstrated that the light absorption of rubrene prevents the photodetector from obtaining a fast response. With the help of magnetic field effect study, it was clearly elucidated that the slow diffusion time of the long lifetime triplet excitons generated from singlet fission in rubrene limited the bandwidth of the device. Moreover, the simulation of the response of photodetector under transient and steady state by exciton transport-diffusion equation showed that the exciton dissociation efficiency in rubrene increases more quickly than that in C-60, which should account for the negative dependence of bandwidth on the reverse bias in rubrene-based device. (C) 2014 AIP Publishing LLC.
Idiotype suppression. II. Amplification of a suppressor T cell with anti‐idiotypic activity (1975)

Abstract Guinea pig IgG 2 anti‐idiotypic antibody (āId2) against the strain A/J antibody A5A has a suppressive effect on the expression of the A5A idiotype in adult A/J mice immunized with Group A streptococci. High doses of āId2 cause an immediate but transient suppression, whereas low doses of āId2 result in a delayed but chronic suppression which lasted for more than 1 year without any indication of recovery. Chronic suppression is transferred by as few as 10 5 spleen cells, but an interval of 6 weeks after transfer is required for completion of suppression. The suppressive capacity of āId2‐induced suppressor cells was virtually inexhaustable in 4 consecutive transfers spaced at 3 month intervals. The suppressor cell is a T cell which adheres to histamine‐rabbit serum albumin‐Sepharose 2B columns.
Analytical prediction of height-velocity diagram of a helicopter using optimal control theory (1991)

The autorotative landing of a single-engine helicopter following power failure is analyzed using optimal control theory. The optimization problems are formulated to minimize the unsafe region in the height-velocity diagram under the condition that the touchdown speed is within the capability of the landing gear. Nonlinear equations of motion are described using a rigid-body dynamic model with longitudinal three degrees of freedom. The aerodynamic model of the rotor takes account of the effects of blade stall during descent and increased induced flow in the vortex ring state. The present method gives a good estimation of the height-velocity boundary in comparison with the existing flight test data. It is pointed out that the test pilot started the collective flare earlier than that occurred in the optimal solution.
Compaction of Topological Quantum Circuits by Modularization (2019)

A topological quantum circuit is a representation model for topological quantum computation, which attracts much attention recently as a promising fault-tolerant quantum computation model by using 3D cluster states. A topological quantum circuit can be considered as a set of “loops,” and we can transform the topology of loops without changing the functionality of the circuit if the transformation satisfies certain conditions. Thus, there have been proposed many researches to optimize topological quantum circuits by transforming the topology. There are two directions of research to optimize topological quantum circuits. The first group of research considers so-called a placement and wiring problem where we consider how to place “parts” in a 3D space which corresponds to already optimized sub-circuits. The second group of research focuses on how to optimize the structure and locations of loops in a relatively small circuit which is treated as one part in the above-mentioned first group of research. This paper proposes a new idea for the second group of research; our idea is to consider topological transformations as a placement and wiring problem for modules which we derive from the information how loops are crossed. By using such a formulation, we can use the techniques for placement and wiring problems, and successfully obtain an optimized solution. We confirm by our experiment that our method indeed can reduce the cost much more than the method by Paetznick and Fowler.
Fast polynomial regression transform for video database (2002)

Important issues in multimedia information systems are the development of efficient storage layout models and effective retrieval system to manage multimedia databases. In multimedia information systems, the capability for interaction with video media type is still extremely limited due to a huge amount of video databases. We present the Fast Polynomial Regression Transform (FPRT) based metadata scheme for manipulating the large video database in the paper. This new metadata scheme provides the simplification of the query mechanism and the improvement of communication in multimedia systems. The main advantage of the proposed approach is the reduction of the data storage space while preserving much video content information. Other advantages are computational simplicity for video information coding and accuracy for video indexing. Visual tools for video representation and browsing are also presented.
The Effect of Alterations in the Pituitary-Thyroid Axis on Hypothalamic Content and in Vitro Release of Somatostatin-Like Immunoreactivity* (1980)

The role of somatostatin (SRIF) in the regulation of thyroid homeostasis was studied by measuring hypothalamic SRIF-like immunoreactivity (SRIF-LI) content and in vitro release in hypothyroid (T3-treated and untreated), euthyroid, and T3-treated normal rats. Hypothalamic SRIF-LI content was decreased in hypothyroid rats and was restored to euthyroid levels by T3 treatment. SRIF-LI release from hypothalami of hypothyroid rats was decreased compared to that in euthyroid controls under basal and stimulated (60 mM K+ or 10(-6) M dopamine) in vitro conditions. The release of SRIF-LI from hypothalami of hypothyroid rats treated with T3 was restored to euthyroid levels. The release of SRIF-LI from normal rat hypothalami was unaffected by TRH or TSH but was stimulated by T3. These results suggest that T3 exerts its negative feedback effect on pituitary TSH release via stimulation of hypothalamic SRIF release as well as by a direct pituitary effect, and that the elevated TSH levels seen in primary hypothyroidism may result in part from a decrease in the tonic inhibitory effect of hypothalamic SRIF. Pancreatic, but not antral or colonic, SRIF-LI was increased in hypothyroid rats, and the levels were reduced by T3 treatment. The changes cannot be explained by alterations in food intake and may represent primary effects of the hypothyroid state.
Using program slicing to simplify testing (1995)

Abstract Program slicing is a technique for automatically identifying the statements of a program which affect a selected subset of its variables. A large program can be divided into a number of smaller program (its slices), each constructed for different variable subsets. The slices are typically simpler than the original program, thereby simplifying the process of testing a property of the program which only concerns the corresponding subset of its variables. However, some aspects of a program's computation are not captured by a set of variables, rendering slicing inapplicable. To overcome this difficulty a program can be rewritten in a self‐checking form by the addition of assignment statements to denote these ‘implicit’ computations. Initially this makes the program longer. However, slicing can now be applied to the introspective program, forming a slice concerned solely with the implicit computation. The simplification power of slicing is then improved using program transformation. To illustrate this approach, the implicit computation which dictates whether or not a program is robust is taken as an example. Whether or not a program is robust is not generally decidable making the approach described here particularly appealing because the slices constructed are approximate answers to the undecidable question ‘Is the program p robust?’.