gebhart/patrepeval huggingface dataset:
Bone Regeneration Within a Coralline Hydroxyapatite Implant (1979)

The hypothesis that incomplete resorption of osteons in an autogenous cortical bone graft may limit its replacement by new bone regeneration was explored by implanting a hydroxyapatite replica of a coral skeletal structure into bone gaps. This implant contained channels and interconnections similar to those in osteon-evacuated bone grafts. In 6 implanted mandibular defects in dogs, two of which were examined at two, 4, and 6 months, 11 percent, 46 percent, and 88 percent of the implant areas were filled with regenerated bone. The regenerated bone was a woven type at two months, but changed to a lamellar type by 6 months. In two implanted defects examined at 12 months, biodegradation of 29 percent of the implant had occurred. The bone regeneration was physiological, the implant was biocompatible, and the biodegradation began after the bone had regenerated.
Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function. (1977)

A new, nondestructive, plasma extraction technique ultilizing chloroform:isopropyl alcohol (1:1) and ammonium sulfate saturation has been devised to isolate adriamycin and its metabolites from human plasma. Adriamycin was the most prominent species in plasma. It disappeared according to a triphasic pattern with a mean half-life of 30 hr. Six metabolites have been clearly separated from adriamycin by thin-layer chromatography. Three were aglycones and three were polar metabolites, one of which has been identified as adriamycinol. All metabolites appeared rapidly in plasma and disappeared according to a biphasic or tri-phasic pattern. The polar metabolites in plasma were found in similar relative concentration to those in urine. In contrast to the small Quantities of aglycones in urine, however, significant concentrations of aglycones were found in plasma. The least prominent metabolite was adriamycin aglycone; the most prominent metabolite was a less polar aglycone, most likely deoxyadriamycin aglycone, and a more polar aglycone, presumably demethyl deoxyadriamycinol aglycone, was the only metabolite to show variable pharmacokinetics in different patients. The nondestructive plasma extraction technique has verified the presence of extensive human metabolism of adriamycin and demonstrated the presence of aglycone and polar metabolites.
Sub–10 nm polyamide nanofilms with ultrafast solvent transport for molecular separation (2015)

Membranes with unprecedented solvent permeance and high retention of dissolved solutes are needed to reduce the energy consumed by separations in organic liquids. We used controlled interfacial polymerization to form free-standing polyamide nanofilms less than 10 nanometers in thickness, and incorporated them as separating layers in composite membranes. Manipulation of nanofilm morphology by control of interfacial reaction conditions enabled the creation of smooth or crumpled textures; the nanofilms were sufficiently rigid that the crumpled textures could withstand pressurized filtration, resulting in increased permeable area. Composite membranes comprising crumpled nanofilms on alumina supports provided high retention of solutes, with acetonitrile permeances up to 112 liters per square meter per hour per bar. This is more than two orders of magnitude higher than permeances of commercially available membranes with equivalent solute retention.
<strong>The Bryoflora of Fernando de Noronha, Brasil</strong> (1991)

Twenty-two species of bryophytes are reported from Fernando de Noronha. One of these, Fissidens veracruzensis Pursell, has not been reported previously from Brasil
Isolation and characterization of trypsin inhibitor from opaque-2 corn seeds. (1977)

Trypsin inhibitor was isolated from seeds of opaque-2 corn by affinity chromatography on a trypsin/Sepharose column. The two major forms of inhibitor eluted from the affinity column were separated by DEAE-cellulose chromatography in the presence of urea. One form of inhibitor is a single-chain protein that has a molecular weight of approximately 12,500; the second inhibitor has two polypeptide chains and appears to have been produced from the single-chain inhibitor by exposure to trypsin in the affinity chromatography step. The relationship of the inhibitor isolated from opaque-2 corn to an inhibitor previously isolated from an unspecified strain of maize by Hochstrasser et al. (Hochstrasser, K., Muss, M., and Werle, E. (1967) Z. Physiol. Chem. 348, 1337-1340) is discussed.
Evaluation of Catalysts for Catalytic Cracking (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvaluation of Catalysts for Catalytic CrackingA. R. Rescorla, J. H. Ottenweller, and R. S. FreemanCite this: Anal. Chem. 1948, 20, 3, 196–202Publication Date (Print):March 15, 1948Publication History Published online1 May 2002Published inissue 15 March 1948https://doi.org/10.1021/ac60015a005RIGHTS & PERMISSIONSArticle Views73Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (944 KB) Get e-Alerts Get e-Alerts
Session Splice on Multimedia Communication for Mobile Computing (2006)

Playing multimedia data with mobile devices is the trend in mobile computing. However, roaming around networks has the session continuity problem because of Internet routing fundamentals. We propose the session splice on multimedia communication for session continuity. It has following advantages: 1) operating without Mobile IP nor the triangular route problem, 2) leaving applications unchanged to keep the compatibility, 3) having no need to deploy external proxies, and 4) hiding movements from applications so applications or users do not need to rejoin sessions at the communication handoff. We implement the session splice in Windows 2000/XP and have experiments to show that the session splice with the negligible overhead can conserve home network bandwidth and maintain stable variation of packet round trip time.
Studies in the Naphthalene Series. III. Synthesis of Apogossypol Hexamethyl Ether<sup>1</sup> (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies in the Naphthalene Series. III. Synthesis of Apogossypol Hexamethyl Ether1J. D. Edwards Jr. and J. L. CashawCite this: J. Am. Chem. Soc. 1957, 79, 9, 2283–2285Publication Date (Print):May 1, 1957Publication History Published online1 May 2002Published inissue 1 May 1957https://pubs.acs.org/doi/10.1021/ja01566a071https://doi.org/10.1021/ja01566a071research-articleACS PublicationsRequest reuse permissionsArticle Views201Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Optimal allocation and binding in high-level synthesis (1992)

The authors present an integer linear program (ILP) formulation for the allocation and binding problem in high-level synthesis. Given a behavioral specification and a time-step schedule of operations, the formulation minimizes wiring and multiplexer areas. An ILP model for minimizing multiplexer and wiring areas has been mathematically formulated and optimally solved. The model handles chaining, multi-cycle operations, pipelined modules, conditional branches and trades off wiring area with resource area. >
Effect of dried garlic powder tablets on postprandial increase in pulse wave velocity after a fatty meal: preliminary observations (2005)

Background: Garlic and sulfur-containing components of garlic have been reported to stimulate nitric oxide synthesis in the endothelium. Nitric oxide production is an important determinant of arterial stiffness. Objective: To examine the impact of dried garlic powder tablets on arterial stiffness as assessed by measurements of pulse wave velocity (PWV). Design: Two separate randomized cross-over studies of healthy people (trial I: n=13; trial II: n=9) were conducted. On separate days, participants consumed a high-fat meal (50 g fat) supplemented with garlic powder tablets (8.4 mg alliin), and an identical, but unsupplemented meal. PWV (m s-1) was measured immediately before and 2-3 h after the test meal. Results: The unsupplemented fatty meal resulted in a significant 5_/6% postprandial increase in PWV in both trials (I: +0.19 m s-1, p=0.04; II: +0.21 m s-1, p=/0.02). In contrast, the supplemented meal was not associated with any postprandial PWV changes in either trial (I: -0.02 m s-1, p=0.31; II: 0.00 m s-1, p=0.95). In pooled analysis (trials I and II), the inhibitory effect of garlic powder on the fatty meal-induced postprandial PWV increase was statistically significant (+0.20 m s-1 vs -0.01 m s-1, p=/0.01). Conclusions: The postprandial increase in PWV associated with consumption of a high-fat meal seems to be prevented by dried garlic powder supplementation. Larger, blinded and placebo-controlled trials are needed to confirm the possible antiatherogenic effect. Keywords: alliin; arterial compliance; arterial stiffness; atherosclerosis; coronary heart disease; nitric oxide.
PP.22.03 (2015)

Objective: Alterations in blood volume management, either by its real expansion or by the volume redistribution from the venous compartment -in a context of low arterial compliance- could be cause of uncontrolled hypertension (UH). a-To evaluate associations between the central blood volume and its redistribution during standing position with blood pressure (BP) b-To determine the prevalence of volume redistribution inhibition during standing in UH c-To identify independent predictors of UH. Design and method: Of 198 subjects evaluated, and after applying exclusion criteria (secondary hypertension, diabetes, kidney disease, adrenergic blockers) 84 were included: 20 normotensives (47.6 ± 9.6 years, 121.8 ± 11.6/73.8 ± 6.1 mm Hg, 37% female) and 64 hypertensives (56.4 ± 12.3 years,142.3 ± 17.0/84.8 ± 10.5 mm Hg, 44% female) treated with two drugs (RAAS-blockers plus Thiazides or CCB's). BP (ESH) and impedance cardiography were determined, with measurements of thoracic fluid content (TFC: 1/ thoracic impedance, 1/mOhm) in lying/standing positions, besides the total arterial complacency index (TACI, ml/mm Hg) and pre-ejection period (PEP, mseg) as sympathetic tone marker. The lying-standing difference of TFC (TFCdiff, venous redistribution capacity) was calculated. Correlations between TFC/TFCdiff with mean-BP (Pearson) were evaluated. TFCdiff was dichotomized according to sex through a Z-score. Integrating both populations, two groups (+TFCdiff, positive redistribution; -TFCdiff, negative redistribution) were defined, determining their respective prevalences in UH (SBP > 139 mm Hg and/or DBP > 89 mm Hg),(chi2). Finally, UH predictors were assessed by logistic regression. Results: TFC was not associated with mean-BP (r = −0.12, p = 0.27). TFCdiff correlated inversely and significantly with mean-BP (r = −0.34, p = 0.001). Mean values of TFCdiff were 3.1 mOhm in men and 3.7mOhm in women. The prevalence of -TFCdiff was significantly elevated in UH (-TFCdiff: 82.1.% vs. + TFCdiff: 17.9%, p = 0.001). In logistic regression, PEP, TFCdiff, TACI and female sex were independent predictors of UH (image on the following page).Conclusions: We found no relationship between the central blood volume and BP. In contrast, the redistribution of blood volume during standing was inversely and significantly associated with BP. The inability of redistribution of central blood volume was almost constant in uncontrolled hypertensives. A high sympathetic tone, along with low compliances in venous and arteriolar territories, could induce uncontrolled hypertension.
S-nitrosoproteome in Endothelial Cells Revealed by a Modified Biotin Switch Approach Coupled with Western Blot-Based Two-Dimensional Gel Electrophoresis (2009)

NO-mediated S-nitrosation of cysteine residues has been recognized as a fundamental post-translational modification. S-Nitrosation of endothelial cell (EC) proteins can alter function and affect vascular homeostasis. Trace amounts of S-nitrosoproteins in endothelial cells (ECs) in vivo coupled with lability of the S-nitroso bond have hindered a comprehensive characterization. We demonstrate a convenient and reliable method, requiring minimal sample, for the screening and identification of S-nitrosoproteins. ECs treated with the NO donor S-nitroso-N-acetylpenicillamine (SNAP) were subjected to the biotin switch method of labeling, then detected by analytical Western blot-based two-dimensional gel electrophoresis (2-DE). More than 89 SNAP-increased S-nitrosoproteins were detected and 28 of these were successfully excised from preparative 2-DE gel and identified by LC-MS/MS. Moreover, the nitrosocysteine residue for each protein (HSPA9/368, beta-actin/16, TMP3/170, vimentin/328) was also determined, and the relative ratio of S-nitrosation/non-S-nitrosation for Cys328 of vimentin was estimated using MASIC software. By the combination of the biotin switch method with 2-DE and Western blot analysis, S-nitrosoproteins can be screened and characterized by MS, providing a basis for further study of the physiological significance of each S-nitrosoproteins.
The Heritability of Bipolar Affective Disorder and the Genetic Relationship to Unipolar Depression (2003)

As defined by the DSM-IV, BPD is highly heritable. There are substantial genetic and nonshared environmental correlations between mania and depression, but most of the genetic variance in liability to mania is specific to the manic syndrome.
Some aspects of traffic management in frame relay networks (1991)

Frame relay is a high speed packet switching technology which has evolved as part of narrowband ISDN. The maximum link access speed is 2 Mbps, as in primary rate ISDN, and the access protocol is LAPD-based. Multiplexing of logical channels is therefore a layer 2 function which obviates the need for any layer 3 processing at network nodes. In addition, when frame relay is compared with X.25, only a sub-set of layer 2 functions are implemented in the network. The paper has proposed a call classification scheme which is considered to be appropriate for frame relay networks, and suggested how nodes which deal with such a traffic mix may be managed. A service mechanism has been proposed and a new congestion notification and recovery scheme which discards out-of-sequence frames in the network has been explained. The technique uses Recovery and Recovery Needed flags in frames and node switch tables, respectively. Further study of this new strategy is needed, but independently organised tests have indicated that it allows a node to maintain maximum throughput for a range of overload conditions.
An overview of the latest development of microencapsulation for agricultural products (1996)

Abstract For the production of controlled‐release agricultural formulations microencapsulation technologies are now the most used. Over the past two decades enormous progress has been made in order to develop the technologies which allow us to produce formulations tailor made to reach the target and fitting our toxicological requirements. This lecture is devoted to the definition of the criteria for selection of an active ingredient for microencapsulation and to a detailed review of the various techniques used today in commerçai microencapsulated formulations. Resources are increasingly allocated into microencapsulation research & development by many agrochemical companies. Therefore the next 20 years should continue to yield innovative ideas including significant improvement of the physico‐chemical and toxicological properties of the actual formulations on the market. Some of this new ideas are applied by our company in order to modify or improve those properties playing the key role in the intent for targeted activity: √ Recombination during production or upon storage. New protective colloides Dermal toxicity (LD 50) ‐ secondary protective colloides. √ Release rate parameters. Modification by the change of mobility of the active ingredient from the core (solvent or fluid type) affecting transit time and therefore LD 50 values. √ Oral toxicity (LD 50). Graft copolymers irreversibly adsorbed to the capsule surface. Key words: microencapsulationcontrol releaserecombinationprotective colloidesmobilitygraft copolymersdermal and oral toxicity
Is Molecular Weight or Degree of Polymerization a Better Descriptor of Ultrasound-Induced Mechanochemical Transduction? (2016)

A detailed understanding of the fundamental processes that govern mechanical transduction in covalent polymer mechanochemistry is essential to advance innovation in this field. In contrast to progress in the development of new mechanophores, the influence of polymer structure and composition on mechanochemical activity has received relatively little attention. In order to address this gap in knowledge, a continuous flow system with synchronous UV-vis absorption capabilities was designed to quantify the ultrasound-induced mechanical activation of a spiropyran mechanophore in real-time. Measurements of reaction kinetics with polymer tethers of varying repeating unit structure demonstrate that degree of polymerization is the key descriptor of mechanochemical activity, independent of molecular weight and pendant group constitution. These results have important implications for the rationalization of mechanochemical properties and the design of new mechanochemically active polymer systems.
Caracterização química e física de frutos de diferentes acessos de tomateiro em casa de vegetação (2011)

O tomate (Solanum lycopersicon) é cultivado em grande escala na agricultura brasileira sendo uma das culturas mais difundidas em todo mundo. Por se tratar de uma cultura de ciclo relativamente curto e de altos rendimentos, a cultura do tomate tem boas perspectivas econômicas e a área cultivada vem aumentando a cada dia. Objetivou-se com este trabalho avaliar as características físicas e químicas de frutos de diferentes acessos de tomateiro nas condições de casa de vegetação em Boa Vista-RR. Foram avaliados seis acessos, sendo: 18 (tomate cereja), 209 (tomate cereja), 243 (CNPH 738), 101 (tomate Santa Cruz-KADA), 102 (tomate Yoshimatsu) e 246 (CNPH 0171). O experimento foi conduzido em um delineamento inteiramente casualizado com seis tratamentos e quatro repetições. Os frutos no ponto de colheita, devidamente identificados foram colhidos e avaliados quanto às seguintes características: teor de vitamina C, pH, acidez titulável, sólidos solúveis, relação sólidos solúveis/acidez titulável, massa fresca, diâmetro transversal e longitudinal do fruto, espessura do pericarpo e teor de matéria seca. Os dados obtidos foram submetidos à análise de variância e as médias comparadas pelo teste de Duncan a 5% de probabilidade. Excetuando-se a variável teor de sólidos solúveis totais, as demais variáveis estudadas apresentaram diferenças estatísticas. Todos os acessos apresentam atributos próprios para consumo in natura. Com exceção dos acessos 101 e 102, devido ao pH elevado (acesso 101) e baixo teor de matéria seca (acesso 101 e 102), os demais apresentam atributos próprio para processamento industrial.
Pseudo-Random Number Generator Based on Binary and Quinary Maximal-Length Sequences (1979)

A new pseudo-random generator for decimal numbers is presented. A sequence of decimal digits is obtained by combining a binary and a quinary maximal-length sequence generated by feedback shift-register circuits. The autocorrelation sequence (ACS) of the resulting decimal sequence is calculated; it shows that linear dependencies are extremely small. Finally, guidelines are developed for choosing feedback polynomials which yield low cross correlation between various sequences of decimal digits.
Motion robust imaging for continuous intraoperative MRI (2001)

The sensitivity of MR imaging to motion and susceptibility normally requires that the physician using intraoperative MRI cease surgical activity while image data sets are acquired. We demonstrate that line scan imaging allows the physician to continue operating without the delays caused by imaging. Consequently, patient anesthesia, surgery, and operating room time can be reduced. J. Magn. Reson. Imaging 2001;13:158-161.