gebhart/patrepeval huggingface dataset:
Lateral charge carrier diffusion in InGaN quantum wells (2012)

Abstract We investigated lateral charge carrier transport in indium gallium nitride InGaN/GaN multi‐quantum wells for two different samples, one sample emitting green light at about 510 nm and the other emitting cyan light at about 470 nm. For the cyan light emitting sample we found a diffusion constant of 1.2 cm 2 /s and for the green light emitting sample 0.25 cm 2 /s. The large difference in diffusion constant is due to a higher point defect density in the green light emitting quantum wells (QWs) as high indium incorporation tends to reduce material quality.
The ROR1 pseudokinase diversifies signaling outputs in MET‐addicted cancer cells (2014)

MET is a master gene controlling a genetic program driving proliferation, apoptosis protection and invasion. The ROR1 pseudokinase acts as a MET substrate. However, its contribution to MET signaling and MET-dependent biological outcomes remains to be elucidated. By structure-function analysis of ROR1 mutants, we show that ROR1 encompasses two major substrate regions: one is located in the proline-rich domain and is directly phosphorylated by MET; the other resides in the pseudokinase domain and is phosphorylated through intermediate activation of SRC. Differential phosphorylation of these two regions dictates the execution of specific responses: phosphorylation of the ROR1 proline-rich domain by MET-but not phosphorylation of the pseudokinase domain by SRC-is necessary and sufficient to control MET-driven proliferation and protection from apoptosis. Differently, both the proline-rich and the pseudokinase domains mediate cell invasion. Consistent with the role of ROR1 in specifying the functional consequences of MET-dependent signals, ROR1 silencing leads to selective attenuation of only some of the signal transduction pathways sustained by MET. These data enlighten the so far elusive function(s) of pseudokinases and identify a mechanism of biological diversification, based on substrate specificity of oncogenic kinases.
Reseña histórico-jurídica de la territorialidad atacameña(siglos XVI-XXI): de leyes y titulaciones interculturales (2006)

El proceso de titulacion de las tierras comunitarias y patrimoniales atacamenas durante la ultima decada obliga a reflexionar sobre algunos de los repertorios propietarios que, desde la epoca colonial, se han ido integrando y diferenciando asociados a practicas, conocimientos y valores distintivos aunque no incompatibles. Las leyes, procesos y artefactos de titulacion formal, configuran una arena de negociacion historica en que se plasman diversos reclamos territoriales indigenas andinos en relacion con funcionarios, mecanismos y objetos estatales (coloniales y postcoloniales). Las correspondientes representaciones e interacciones propietarias locales, regionales y nacionales revelan ciclos de negociacion intercultural, que resultan en simbolos y rituales de apropiacion, titulacion y demarcacion formal de tierras indigenas. El caso atacameno se organiza en facciones politicas competitivas que tienden hacia relaciones de pronunciada jerarquia. Los escenarios de conflicto por recursos territoriales en consideracion, contribuyen a la comprension de los complejos procesos internormativos de comunicacion y diferenciacion territorial, politica y economica, los que hoy se precisan en tanto frontera post-colonial atacamena.
Oral health promotion by the oral health products industry: unrecognised and unappreciated? (2008)

There is often ambivalence in the way dentists view the oral health care industry. On the one hand, there are the skeptics who view corporate activities as suspect, calling into question the validity of industry-sponsored research and considering all promotional activities as self-serving. On the other hand, there are those who will evaluate research, whether industry sponsored or not, on its merits and appreciate corporate philanthropy that aims to give something back to the profession, although at times the expectations of the amount of financial support available are markedly in excess of the actual amount based on dental product sales. (Yes--and don't let your young children see this!--the tooth fairy who goes around dispensing endless number of dollars or pounds or euros does not actually exist!) Recognizing that, of necessity, corporations exist to make a profit, I would submit that the relationship of responsible companies to the profession can often be looked at as a partnership in which both sides benefit. Ultimately, all have as a goal the improvement of the oral health of our patients (or consumers) which is facilitated by the availability of effective products. In addition to marketing products, the oral care industry plays a large, though oftentimes unnoticed, role in oral health promotion. For the most part, this involves targeted financial support or contributions of products that serve to enhance patients' understanding of oral diseases and the need for good oral care, and/or provide access to care for underserved groups. In the following sections, I will give some examples of industry-supported health promotion activities, most of which will be activities in the United States with which I am most familiar. These are examples only--the list is not intended to be exhaustive and a company's name will be included in only the few instances in which it is an integral part of the programme title.
Effects of Chemical Application on Antifouling in Steam-Assisted Gravity Drainage Operations (2005)

The fouling behavior of water streams in steam-assisted gravity drainage (SAGD) operations can be affected by chemical selection, including a reverse emulsion breaker, demulsifier, flocculant, and dispersant. Reverse emulsion breakers and demulsifiers were chosen to give the cleanest water quality and best dehydration during laboratory testing of reverse emulsions produced at SAGD facilities. A group of polyquaternary amine reverse emulsion breakers were synthesized to have a range of molecular weights with equivalent charge densities. The effect of their molecular weights on water clarification was investigated by standard bottle testing. It was found that the higher the molecular weight, the more effective the chemical was at removing suspected fouling agents. A flocculant has to be used with care to avoid overtreatment of the system. If fouling occurs during normal operation due to produced water from the primary separation vessel containing residual amounts of oil or other impurities, remediation can be used to address the fouling. A series of dispersants were tested to check if the oil could be kinetically stabilized in the produced water phase. It was shown that decreased viscosity of the oil increased the tendency for the oil to be dispersed. Certain surfactants helped the oil to be dispersed into the water and then to be released upon settling for 30 min. This type of dispersant could be applied in any SAGD operation with heat exchanger fouling problems.
Multidisciplinary aerospace design optimization - Survey of recent developments (1996)

The increasing complexity of engineering systems has sparked increasing interest in multidisciplinary optimization (MDO). This paper presents a survey of recent publications in the field of aerospace where interest in MDO has been particularly intense. The two main challenges of MDO are computational expense and organizational complexity. Accordingly the survey is focussed on various ways different researchers use to deal with these challenges. The survey is organized by a breakdown of MDO into its conceptual components. Accordingly, the survey includes sections on Mathematical Modeling, Design-oriented Analysis, Approximation Concepts, Optimization Procedures, System Sensitivity, and Human Interface. With the authors' main expertise being in the structures area, the bulk of the references focus on the interaction of the structures discipline with other disciplines. In particular, two sections at the end focus on two such interactions that have recently been pursued with a particular vigor: Simultaneous Optimization of Structures and Aerodynamics, and Simultaneous Optimization of Structures Combined With Active Control.
Trauma Practice in the Wake of September 11, 2001 (2002)

Abstract The attacks of September 11th, 2001 were unprecedented in several respects. They were the first attacks on U.S. soil by a foreign power in several generations, were witnessed live on television throughout the U.S. and the world, and shattered widely held assumptions about security in the U.S. and, by implication, elsewhere. Some questions and challenges evoked by the events of September 11th of particular relevance to trauma practitioners are discussed. The contents of Trauma Practice in the Wake of September 11, 2001, are summarized and framed as representing a preliminary attempt to respond to some of these questions. Finally, some of the opportunities created by the September 11th attacks-increasing public awareness of trauma and its impact, fostering compassion for victims of various types of trauma, and strengthening international collaboration among traumatologists and advocates of world peace-are considered.
Nutlin-3a Is a Potential Therapeutic for Ewing Sarcoma (2010)

Our findings suggest that p53-dependent apoptosis is the primary cellular response of Ewing sarcoma cell lines following exposure to Nutlin-3a. Furthermore, Nutlin-3a can synergize with the current Ewing sarcoma chemotherapy protocols, suggesting p53 activation as a novel systemic therapeutic approach for this disease.
Efficacy of Calcium and Sodium Hypochlorite for Seed Treatment of Pepper1 (1973)

Abstract Seeds of pimiento pepper ( Capsicum annuum L.) artificially inoculated with Xanthomonas vesicatoria (Doidge) Dows., were disinfected by a 4.20% calcium hypochlorite solution or a 2.63% sodium hypochlorite solution for 15 minutes followed by a 15 minute water-rinse. Germination after 14 days was not reduced.
Long-range activation of Sox9 in Odd Sex (Ods) mice (2004)

The Odd Sex mouse mutation arose in a transgenic line of mice carrying a tyrosinase minigene driven by the dopachrome tautomerase (Dct) promoter region. The minigene integrated 0.98 Mb upstream of Sox9 and was accompanied by a deletion of 134 kb. This mutation causes female to male sex reversal in XX Ods/+ mice, and a characteristic eye phenotype of microphthalmia with cataracts in all mice carrying the transgene. Ods causes sex reversal in the absence of Sry by upregulating Sox9 expression and maintaining a male pattern of Sox9 expression in XX Ods/+ embryonic gonads. This expression, which begins at E11.5, triggers downstream events leading to the formation of a testis. We report here that the 134 kb deletion, in itself, is insufficient to cause sex reversal. We demonstrate that in Ods, the Dct promoter is capable of acting over a distance of 1 Mb to induce inappropriate expression of Sox9 in the retinal pigmented epithelium of the eye, causing the observed microphthalmia. In addition, it induces Sox9 expression in the melanocytes where it causes pigmentation defects. We propose that Ods sex reversal is due to the Dct promoter element interacting with gonad-specific enhancer elements to produce the observed male pattern expression of Sox9 in the embryonic gonads.
Narrow linewidth intervalence-band emission from germanium terahertz lasers (2003)

We demonstrate narrow linewidth emission from p-Ge terahertz lasers at low magnetic fields where intervalence-band emission dominates. The volume of these laser crystals is 32 mm3, which is one order of magnitude smaller than the lasers for which the emission spectrum has been measured previously. The frequencies emitted are shown to be selected by the optical cavity and do not shift with the magnetic field, as has been observed for larger laser crystals.
Safety critical systems (1990)

Abstract On the stairs and landing of my cottage I have four light-bulbs. A few weeks ago the landing went dark. No, it was not a blown fuse, but the fourth light bulb gone. As technical coordinator for the DTI-SERC Safety Critical Systems Research Programme I smiled — wanly, as they say.
Systematic Status of Dipodomys Merriami Ambiguus Merriam (1941)

Systematic Status of Dipodomys merriami ambiguus Merriam Get access William B. Davis William B. Davis Texas Cooperative Wildlife Research Unit, College Station, Texas Search for other works by this author on: Oxford Academic Google Scholar Journal of Mammalogy, Volume 22, Issue 2, 14 May 1941, Pages 192–194, https://doi.org/10.2307/1374917 Published: 14 May 1941
The Great National Project: A History of the Chesapeake and Ohio Canal. By Walter S. Sanderlin. [The Johns Hopkins University Studies in Historical and Political Science, Series 64, No. 1.] Baltimore: The Johns Hopkins Press, 1946. Pp. 331. $3.00. (1948)

The Great National Project: A History of the Chesapeake and Ohio Canal. By Walter S. Sanderlin. [The Johns Hopkins University Studies in Historical and Political Science, Series 64, No. 1.] Baltimore: The Johns Hopkins Press, 1946. Pp. 331. $3.00. - Volume 8 Issue 1
Moving Target Indication and Tracking from Moving Sensors (2005)

This paper describes a moving target indication and tracking system developed for acquiring and tracking targets in video from moving sensors, in particular airborne urban surveillance video. The paradigm of the moving sensor, which is a typical scenario in defence applications (e.g. UAV surveillance video), poses some unique problems as compared to the stationary sensor. Our solution draws on a number of algorithms from the vision and tracking communities and combines them as a novel solution to the problem. Moreover, given a suitable cluster of conventional hardware, the system allows a near real-time solution to MTI.
Carotid baroreceptor reflex coronary vasodilation in the dog. (1985)

The hypothesis that neurally mediated coronary vasodilation occurs as part of the carotid baroreceptor reflex was investigated. The left main coronary artery was cannulated and perfused at constant pressure (100 mm Hg) in closed-chest, chloralose-anesthetized dogs. The heart was paced at a constant rate between 60 and 70 beats/min after atrioventricular heart block. Propranolol (1 mg/kg) was given to prevent beta-receptor-mediated alterations in contractility. Aortic blood pressure was stabilized with a blood reservoir. The aortic depressor nerves were cut bilaterally to prevent the buffering influence of aortic arch baroreceptors on the carotid baroreceptor reflex. The carotid sinuses were vascularly isolated and perfused with arterial blood at controlled pressures. Under these conditions, a step change in carotid sinus pressure from 70 to 210 mm Hg produced a 0.29 ml/min per g increase in coronary flow above control and a 10 mm Hg increase in coronary sinus blood oxygen tension. A step in carotid sinus pressure from 70 to 150 mm Hg resulted in a flow increase of 0.13 ml/min per g and a coronary sinus oxygen tension increase of 5.3 mm Hg relative to prestimulation values. Atropine (0.5 mg/kg, iv) blocked most of the reflex coronary vasodilation, indicating a parasympathetic component, and the addition of adrenergic alpha-receptor blockade with phenoxybenzamine (0.25 mg/kg, ic) abolished the remaining response, demonstrating sympathetic participation. The reflex nature of the coronary response was confirmed with carotid sinus denervation and vagotomy. It is concluded that carotid sinus hypertension results in a graded reflex neural coronary vasodilation independent of myocardial metabolic factors. The major component is due to activation of parasympathetic coronary vasodilator fibers, but there is also inhibition of sympathetic vasoconstrictor fibers.
Multi‐level composite nanostructures based on the arrays of vertically aligned carbon nanotubes and planar graphite layers (2010)

Abstract New composite nanostructures based on two allotropic forms of carbon, the arrays of vertically aligned carbon nanotubes (CNTs) and planar graphite layers (PGL) located at the top of the arrays, so‐called “CNT–PGL nanostacks”, have been synthesized by the injection CVD method using xylene/ferrocene solution. Two‐ and three‐level nanostacks were demonstrated. The possible scenario of the growth mechanism of these nanostructures is proposed, that is, each level of the nanostack grows by the simultaneous PGL and CNT array formation on the surface of the catalyst particles previously covered by a graphene layer. At the upper surface of the catalyst particles, which is in direct contact with the reactive species, the graphene layer becomes an origin of PGL, and at the interface between catalyst and substrate it transforms into CNTs. magnified image
On the present state of the savings' bank question (1855)

About three years since, I had the honor of reading before this\nsociety a paper on the duties of the public with respect to charitable\nsavings' banks. Since that time there have been promises of legislation,\nbut nothing has been actually done to remove the general\ninsecurity of the depositors to which I then directed attention. On\nthe contrary, the recent statements of Mr. Gladstone, while Chancellor\nof the Exchequer, have disclosed some facts which will, I\nthink, be as new to you as they were to me, and which place that\ninsecurity in a still stronger point of view.
An Architecture-Tracking Approach to Evaluate a Modular and Extensible Flight Software for CubeSat Nanosatellites (2019)

Delivering better flight software is an important concern to improve CubeSat missions success. It has been identified as a key element to enhance team collaboration, increase reusability, reduce the mission risk, and facilitate the development and operation of new mission concepts, such as satellite mega-constellations. An appropriated fight software architecture represents the functional and non-functional requirements and guides the development. Therefore, to achieve the expected software quality, the architecture should be closely monitored during the entire software life cycle. However, ensuring that a flight software for a spacecraft embedded system closely follows the proposed architecture and addresses the set of non-functional requirements is a difficult and nontrivial problem. Motivated by requirements commonly described in previous CubeSat missions, in this work, we present the design and implementation of a flight software architecture based on the command design pattern. We also present an architecture tracking methodology to verify and control the flight software quality criteria during the development process through the use of graphical software analysis tools and agile programming techniques. This automatic software analysis tool was developed using Git, Jenkins, Moose, and Roassal, and has been applied in the SUCHAI series of nanosatellites to evaluate the impact of the architecture verification during the development history. The implemented flight software and the verification tools have been released as open source platforms and are available for the CubeSat community.
Identification of a Specific Chaperone for SptP, a Substrate of the Centisome 63 Type III Secretion System of <i>Salmonella typhimurium</i> (1998)

Salmonella typhimurium uses of a type III protein secretion system encoded at centisome 63 of its chromosome to deliver effector molecule into the host cell. These proteins stimulate host cell responses such as reorganization of the actin cytoskeleton and activation of transcription factors. One of these effector proteins is SptP, a tyrosine phosphatase that causes disruption of the host cell actin cytoskeleton. A characteristic feature of many substrates of type III secretion systems is their association with specific cytoplasmic chaperones which appears to be required for secretion and/or translocation of these proteins into the host cell. We report here the identification of SicP, a 13-kDa acidic polypeptide that is encoded immediately upstream of sptP. A loss-of-function mutation in sicP resulted in drastically reduced levels of SptP but did not affect sptP expression, indicating that SicP exerts its effect posttranscriptionally. Pulse-chase experiments demonstrated that the loss of SicP leads to increased degradation of SptP. In addition, we show that SicP binds to SptP directly and that the binding site is located between residues 15 and 100 of the tyrosine phosphatase. Taken together, these results indicate that SicP acts as a specific chaperone for SptP.
Echo‐planar spin‐echo and inversion pulses (1993)

The echo-planar k-space trajectory can be used as the basis for any two-dimensional selective pulse. The main application is spectral-spatial pulses, which must be based on the echo-planar trajectory. In this paper we show how echo-planar spin-echo (EPSE) pulses may be designed.
Mid-infrared supercontinuum generation to 45  μm in uniform and tapered ZBLAN step-index fibers by direct pumping at 1064 or 1550  nm (2013)

We present a numerical design optimization of step-index ZBLAN fibers for developing mid-infrared (IR) supercontinuum sources with spectra covering the 1–4.5 μm regime using direct pumping with 10 ps pulses (FWHM) from mode-locked Yb (12.5 kW peak power) and Er lasers (10 kW peak power). Even with optimum NA and core diameter to minimize confinement loss and give the most suitable dispersion and nonlinearity, the Yb pump-laser cannot push the spectrum beyond 1.52 μm, whereas the Er laser can push the spectrum to 4.15 μm. We further consider the optimum placement of a 20 cm taper to broaden the spectrum. This does not considerably broaden the Yb-pumped spectrum, whereas the Er-pumped spectrum can be extended to 4.5 μm through mid-IR dispersive waves and tunneling solitons.
Micro/nanoscale mechanical and tribological characterization of SiC for orthopedic applications (2004)

Micro/nanomechanical and tribological characterization of SiC has been carried out. For comparison, measurements on SiC, CoCrMo, Ti-6Al-4V, and stainless steel have also been made. Hardness and elastic modulus of these materials were measured by nanoindentation using a nanoindenter. The nanoindentation impressions were imaged using an atomic force microscope (AFM). Scratch, friction, and wear properties were measured using an accelerated microtribometer. Scratch and wear damages were studied using a scanning electron microscope (SEM). It is found that SiC exhibits higher hardness, elastic modulus, scratch resistance as well as lower friction with fewer and smaller debris particles compared to other materials. These results show that SiC possesses superior mechanical and tribological properties that make it an ideal material for use in orthopedic and other biomedical applications.
UNDERSTANDING CONSUMERS ATTITUDE TOWARD ADVERTISING (2002)

Literature in advertising and information systems suggests that advertising in both traditional media and the Internet is either easily ignored by the audience or is perceived with little value. However, these studies assumed that the audience was passive and failed to consider the motives of the users. In light of this, the present study measures consumers attitudes toward advertisements for different purposes/functions (brand building and directional) and different media (traditional and Internet-based). Literature suggests the following factors that contribute to consumers perceptions of ads: entertainment, irritation, informativeness, credibility, and demographic. We believe that interactivity is also a factor that contributes to consumers perceptions. By understanding consumers attitude towards advertising, designers and marketers can better strategize their advertising designs. A better understanding of interactivity can also help to improve the effectiveness of interactive media such as the Internet. A methodology for studying the factors that contribute to consumers perceptions of ads is proposed and implications for Internet-based advertising and e-commerce is discussed.