gebhart/patrepeval huggingface dataset:
Submarine cable burying system with guiding equipment (1972)

Burying submarine cables in the sea bottom is indispensable to protect them from injury arising from fishing activities and anchors. The Nippon Telegraph and Telephone Public Corporation has been making continuous efforts to develop a method for burying submarine cables and has recently completed a new system called the "towed attached guiding equipment simultaneous laying-burying system". This paper describes this system and outlines the installation work between Matsuyama and Kure which was recently completed by this system.
Noisy speech recognition using robust inversion of hidden Markov models (2002)

The hidden Markov model (HMM) inversion algorithm is proposed and applied to robust speech recognition for general types of mismatched conditions. The Baum-Welch HMM inversion algorithm is a dual procedure to the Baum-Welch HMM reestimation algorithm, which is the most widely used speech recognition technique. The forward training of an HMM, based on the Baum-Welch reestimation, finds the model parameters /spl lambda/ that optimize some criterion, usually maximum likelihood (ML), with given speech inputs s. On the other hand, the inversion of a HMM finds speech inputs s that optimize some criterion with given model parameters /spl lambda/. The performance of the proposed HMM inversion, in conjunction with HMM reestimation, for robust speech recognition under additive noise corruption and microphone mismatch conditions is favorably compared with other noisy speech recognition techniques, such as the projection-based first-order cepstrum normalization (FOCN) and the robust minimax (MINIMAX) classification techniques.
Applying Machine Learning and Audio Analysis Techniques to Insect Recognition in Intelligent Traps (2013)

Throughout the history, insects have had an intimate relationship with humanity, both positive and negative. Insects are vectors of diseases that kill millions of people every year and, at the same time, insects pollinate most of the world's food production. Consequently, there is a demand for new devices able to control the populations of harmful insects while having a minimal impact on beneficial insects. In this paper, we present an intelligent trap that uses a laser sensor to selectively classify and catch insects. We perform an extensive evaluation of different feature sets from audio analysis and machine learning algorithms to construct accurate classifiers for the insect classification task. Support Vector Machines achieved the best results with a MFCC feature set, which consists of coefficients from frequencies scaled according to the human auditory system. We evaluate our classifiers in multiclass and binary class settings, and show that a binary class classifier that recognizes the mosquito species achieved almost perfect accuracy, assuring the applicability of the proposed intelligent trap.
Micro magnetic stir-bar mixer integrated with parylene microfluidic channels (2004)

Previously, we reported a micro magnetic stir-bar mixer driven by an external rotating magnetic field and its rapid mixing performance in polydimethyl-siloxane (PDMS) channels. The PDMS piece with embedded fluid channels were manually aligned to a glass substrate and assembled. In this paper, we report the fabrication and testing results of a micro magnetic stir-bar monolithically integrated in parylene surface-micromachined channels with improved design features, including small tolerance of the stir-bar to channel wall (10 microm). Using of parylene based microchannels with improved design not only provides improved mixing, but also eliminates certain problems associated with PDMS-based channels. For example, porosity of PDMS causes evaporation and absorption of chemicals and thus channels made of PDMS are prone to cross-contamination. We have also demonstrated that the magnetic stir-bar can be used to pump liquid in micro channels.
A new approach to molecular devices using SAMs, LSMCD and Cat-CVD (2003)

This paper proposes a new technology for the fabrication of molecular devices using nanotechnology based on liquid and surface sciences recently developed, such as the direct patterning of solid surfaces using the difference of hydrophobic and hydrophilic properties of self-assembled mono-layers and self-assembly films of metal nanoparticles, the fine fabrication of films by the method of Liquid Source Misted Chemical Deposition, and the Langmuir–Blodgett self-assembly films. In these liquid-based technologies, various kinds of organic compounds in solutions, including biological systems, can be used as functional materials in molecular devices. In addition, it has been found that the insulating inorganic films obtained by catalytic chemical vapor deposition are quite effective in the protection of molecular devices against water and/or oxygen. We confirm, from the experimental results presented in this report, that this new approach is practically promising in future.
Engraftment of low numbers of pediatric acute lymphoid and myeloid leukemias into NOD/SCID/IL2Rcγnull mice reflects individual leukemogenecity and highly correlates with clinical outcome (2013)

Although immortalized cell lines have been extensively used to optimize treatment strategies in cancer, the usefulness of such in vitro systems to recapitulate primary disease is limited. Therefore, the design of in vivo models ideally utilizing patient-derived material is of critical importance. In this regard, NOD.Cg-Prkdc(scid) IL2rg(tmWjl) /Sz (NSG) mice have been reported to provide superior engraftment rates. However, limited data exist on the validity of such a model to constitute a surrogate marker for clinical parameters. We studied primary and serial engraftment on more than 200 NSG mice with 54 primary pediatric B cell precursor acute lymphatic leukemia (B-ALL), myeloid leukemia (AML) and T cell leukemia (T-ALL) samples, characterized the leukemogenic profile and correlated engraftment kinetics with clinical outcome. Median time to engraftment was 7-10 weeks and 90% of the mice engrafted. Male recipients conferred significantly higher engraftment levels than female recipients (p ≤ 0.004). PCR-based minimal residual disease marker expression and fluorescence in situ hybridization confirmed the presence of patient-specific genetic aberrations in mice. Transcriptome cluster analysis of genes known to be important in the leukemogenesis of all three diseases revealed that well-known tumor-regulating genes were expressed to a comparable extent in mice and men. The extent of engraftment and overall survival of NSG mice highly correlated with the individual prognosis of B-ALL, AML and T-ALL patients. Thus, we propose an in vivo model that provides a valuable preclinical tool to explore the heterogeneity of leukemic disease and exploit patient-tailored leukemia-targeting strategies within multivariate analyses.
Synthesis and binding properties of calix[4]arene telomers (1999)

Two calix[4]arene derivatives (5 and 8) and their telomers are synthesized to estimate selective extraction of alkali and transition metal cations from the aqueous to the organic phase (chloroform). Compound 5 shows selectivity toward Hg2+. Compound 8 and telomers 6 and 9 are not selective but are good extractants for all used transition metal ions. The observations suggest that ethylene glycol bridges are efficient for carrying transition metal cations in a two-phase solvent system. © 1999 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 37: 4351–4355, 1999
A Novel Sparse Channel Estimation Method for Multipath MIMO-OFDM Systems (2011)

Multiple-input multiple-output orthogonal frequency division multiplexing (MIMO-OFDM) is the promising technology for next generation communication systems due to high throughput. Due to the coherent receiving and demodulation at the receiver, accurate channel state information (CSI) is indispensable. Conventional rich assumption-based channel estimators have been proposed at the cost of enough training resource which leads to extra spectrum waste. However, physical measurements have verified that the wireless channels tend to exhibit sparse structure in high-dimensional space, e.g., delay spread, Doppler spread and space spread. Some sparse channel estimation methods for the MIMO-OFDM have been proposed. These estimation methods utilize either greedy algorithm or convex optimization. In this paper, we propose a novel sparse channel estimation method using sparse cognitive matching pursuit (SCMP) algorithm. Compared to other compressive algorithms in the state of art, the major innovation of the SCMP sparse channel estimation method (SCMP-SCE) is the ability of obtaining the accurate CSI without prior information of sparsity. Simulation results confirm that the proposed method has better estimation performance and lower estimation complexity.
Protein-Templated Biomimetic Silica Nanoparticles (2015)

Biomimetic silica particles can be synthesized as a nanosized material within minutes in a process mimicked from living organisms such as diatoms and sponges. In this work, we have studied the effect of bovine serum albumin (BSA) as a template to direct the synthesis of silica nanoparticles (NPs) with the potential to associate proteins on its surface. Our approach enables the formation of spheres with different physicochemical properties. Particles using BSA as a protein template were smaller (∼250-380 nm) and were more monodisperse than those lacking the proteic core (∼700-1000 nm) as seen by dynamic light scattering (DLS), scanning electron microscopy (SEM), and environmental scanning electron microscopy (ESEM) analysis. The absence of BSA during synthesis produced silica nanoparticles without any porosity that was detectable by nitrogen adsorption, whereas particles containing BSA developed porosity in the range of 4 to 5 nm which collapsed on the removal of BSA, thus producing smaller pores. These results were in accordance with the pore size calculated by high-resolution transmission electron microscopy (HTEM). The reproducibility of the BSA-templated nanoparticle properties was determined by analyzing four batches of independent synthesizing experiments that maintained their properties. The high positive superficial charge of the nanoparticles facilitated adsorption under mild conditions of a range of proteins from an E. coli extract and a commercial preparation of laccase from Trametes versicolor. All of the proteins were quantitatively desorbed. Experiments conducted showed the reusability of the particles as supports for the ionic adsorption of the biomolecules. The protein loading capacity of the BSA-based biomimetic particles was determined using laccase as 98.7 ± 6.6 mg·g(-1) of particles.
An improvement of double emulsion technique for preparing bovine serum albumin-loaded PLGA microspheres (2004)

A modified double emulsion technique was adopted to prepare bovine serum albumin (BSA) loaded poly (D,L-lactic-co-glycolic acid) (PLGA) microspheres. In the formulations, polysorbates (Tween) such as Tween20, Tween40 or Tween80, instead of frequently used poly (vinyl alcohol) (PVA), was used as the emulsifier. Microspheres with porous surface, large particle size, low microsphere yield (approximately 65.4%) and BSA entrapment efficiency (approximately 25.2%) were obtained when Tween80 aqueous solution alone was used as the outer aqueous phase. However, microspheres with smooth surface, high yield and BSA entrapment efficiency could be produced successfully by introducing sodium chloride or glucose into the outer aqueous phase. Adding 5.0%(w/v) sodium chloride into the continuous phase led to increase in microsphere yield and BSA entrapment efficiency from 65.4% and 25.2% to approximately 100% and 76.6%, respectively. Microsphere yield and BSA entrapment efficiency increased from 64.5% and 25.2% to 97.2% and 89.3%, respectively, when 15.0%,(w/v) glucose was added into the continuous phase. In constrast to the microspheres prepared in the presence of additive, a more marked burst release was observed for microspheres prepared without additive in the continuous phase, which may be attributed to the porous morphology of the latter.
New branched‐chain fatty acids from the senegalese gorgonian<i>Leptogorgia piccola</i> (white and yellow morphs) (1995)

Fatty acids from total lipids of the gorgonian Leptogorgia piccola (white and yellow morphs), collected from the same area at two different periods with regard to the average water temperature, were studied. More than fifty fatty acids were identified as methyl esters and N-acyl pyrrolidides by gas chromatography and gas chromatography/mass spectrometry. Three new, branched-chain unsaturated fatty acids were identified in addition to the unusual 7-methyl-6-hexadecenoic acid, namely 10-methyl-6-hexadecenoic, 7,9-dimethyl-6-hexadecenoic, and 10-methyl-6,9-heptadecadienoic acids. Also 6,9-heptadecadienoic acid was identified. The fatty acid patterns of specimens harvested in colder waters were quite different from those harvested in warmer waters in that the former contained high amounts of methylene-interrupted polyunsaturated acids, including tetracosapolyenoic acids, especially 6,9,12,15,18-24:5 (up to 15.8% of the total acid mixture) and 6,9,12,15,18,21-24:6 (up to 5.3%). Arachidonic acid was, nevertheless, a major component in all the fatty acid mixtures studied (13.6-20.5%). Based on gas chromatography/Fourier transform infrared experiments, the double bonds were assigned the (Z) configuration. Several fatty aldehydes and their dimethyl acetals were also detected, of which the most abundant was octadecanal.
Oral Calcitriol for Psoriasis (1996)

Calcitriol, the active form of vitamin D3 (1,25-dihydroxyvitamin D3), and its analogues have been used with success, both topically and orally, to
MetalMine: a database of functional metal-binding sites in proteins (2009)

We present a new database called MetalMine that contains the classification of metal-binding sites derived from the structures of protein-metal-ion complexes. Metal-binding sites were automatically extracted from Protein Data Bank (PDB) structures, classified based on the protein domains in which the metal-binding sites are incorporated, and then manually curated. Tentative or artificial metal ion coordinations were excluded during this curation process. On the web pages of the database, the following information about metal-binding sites is presented in a hierarchical manner: the kind of metal ion, metal-binding site typically specified by the name of the protein, and each instance of metal-binding coordinates in the PDB structures. The database search engine currently supports the following two types of queries. First, given the PDB code of a protein–metal–ion complex, it provides a list of metal-binding sites incorporated in the structure file. Second, given an amino acid sequence as a query, it looks for matches with metal-binding residues in the Basic Local Alignment Search Tool (BLAST) sequence alignment. As of October 2009, MetalMine contained 412 classified entries of functional metal-binding sites, which we believe is the largest number of entries in databases available to the public.
Roles for enteric d-type cytochrome oxidase in N2 fixation and microaerobiosis (1990)

Escherichia coli strains that lacked the d-type cytochrome oxidase, the terminal oxidase with a high affinity for O2, grew anaerobically as well as the wild type did and were not impaired in the ability to evolve H2 from either glucose or formate. The anaerobic synthesis and activity of nitrogenase in transconjugants of these strains carrying Klebsiella pneumoniae nif genes were also normal. However, the behavior towards O2 of anaerobically grown bacteria lacking the d-type oxidase differed from that of the wild type in the following ways: the potential O2 uptake was lower, H2 evolution and nitrogenase activity supported by fermentation were more strongly inhibited by O2, and microaerobic O2-dependent nitrogenase activity in the absence of a fermentable carbon source did not occur. These results show that the d-type oxidase serves two functions in enteric bacteria--to conserve energy under microaerobic conditions and to protect anaerobic processes from inhibition by O2.
Gastroesophageal Reflux–Related Chronic Laryngitis: Con (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Otolaryngology–Head & Neck Surgery HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Otolaryngology–Head & Neck Surgery journal
Sponsored Search: Is Money a Motivator for Providing Relevant Results? (2007)

Analysis of data from a major metasearch engine reveals that sponsored-link click-through rates appear lower than previously reported. Combining sponsored and nonsponsored links in a single listing, while providing some benefits to users, does not appear to increase clicks on sponsored listings. In a competitive market, rivals continually strive to improve their information-retrieval capabilities and increase their financial returns. One innovation is sponsored search, an "economics meets search" model in which content providers pay search engines for user traffic going from the search engine to their Web sites. Sponsored search has proven to be a successful business model for Web search engines, advertisers, and online vendors, as well as an effective way to deliver content to searchers. The "impact of sponsored search" sidebar describes some of the model's notable benefits.
Financiación de hospitales y asignación de recursos mediante técnicas multicriterio interactivas (2005)

El objetivo de este trabajo, es aplicar distintos modelos de programacion multicriterio interactivos para determinar sistemas optimos de financiacion de areas o centros sanitarios del Servicio Andaluz de Salud (SAS). Este trabajo continua una linea de investigacion (Martin et all, 2001) que aspira a desarrollar la programacion matematica multicriterio como una poderosa herramienta de analisis para optimizar la toma de decisiones del financiador o regulador publico en el sector sanitario.
Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins. (1994)

Neurexins, a family of neuronal cell-surface proteins, consist of the longer alpha-neurexins (I alpha, II alpha, and III alpha) and the shorter beta-neurexins (I beta and II beta) with identical C termini but distinct N termini. alpha-Neurexins have the structure of cell surface receptors, but the membrane topology and conservation of beta-neurexins is unknown. We have now characterized cDNA clones encoding bovine neurexins I beta and III beta, thereby demonstrating the presence of a beta-form for neurexin III and the evolutionary conservation of beta-neurexins in mammals. Similar to alpha-neurexins, beta-neurexins were found to be highly O-glycosylated after expression by transfection in COS cells, suggesting that alpha- and beta-neurexins utilize the same O-glycosylation cassette and have similar transmembrane orientations. To determine if beta-neurexins contain a cleaved or uncleaved signal sequence for membrane translocation, beta-neurexin-IgG fusion proteins were expressed in COS cells, and their N termini were directly sequenced. This revealed that the N terminus of all three beta-neurexins contains an unusual cleaved signal sequence. Together our data show that all known neurexin genes generate alpha and beta forms with similar transmembrane organizations and receptor-like structures. Due to the presence of a long atypical cleaved signal peptide, beta-neurexins contain only a short unique sequence before splicing into the alpha-neurexin sequence. Thus, beta-neurexins are essentially N terminally truncated alpha-neurexins.
Environmental Organic Chemistry (2002)

Preface. Part I: Introduction. 1. General Topic and Overview. 2. An Introduction to Environmental Organic Chemicals. Part II: Equilibrium Partitioning Between Gaseous, Liquid, and Solid Phases. 3. Partitioning: Molecular Interactions and Thermodynamics. 4. Vapor Pressure. 5. Activity Coefficient and Solubility in Water. 6. Air-Organic Solvent and Air-Water Partitioning. 7. Organic Liquid-Water Partitioning. 8. Organic Acids and Bases: Acidity Constant and Partitioning Behavior. 9. Sorption I: General Introduction and Sorption Processes Involving Organic Matter. 10. Sorption II: Partitioning to Living Media - Bioaccumulation and Baseline Toxicity. 11. Sorption III: Sorption Processes Involving Inorganic Surfaces. Part III: Transformation Processes. 12. Thermodynamics and Kinetics of Transformation Reactions. 13. Chemical Transformations I: Hydrolysis and Reactions Involving Other Nucleophilic Species. 14. Chemical Transformations II: Redox Reactions. 15. Direct Photolysis. 16. Indirect Photolysis: Reactions with Photooxidants in Natural Waters and in the Atmosphere. 17. Biological Transformations. Part IV: Modeling Tools: Transport and Reaction. 18. Transport by Random Motion. 19. Transport Through Boundaries. 20. Air-Water Exchange. 21. Box Models. 22. Models in Space and Time. Part V: Environmental Systems and Case Studies. 23. Ponds, Lakes, and Oceans. 24. Rivers. 25. Groundwater. Appendix. Bibliography. Index (Subject Index, Compound Index, List of Illustrative Examples).
Simple compiler algorithms to reduce ownership overhead in cache coherence protocols (1994)

We study in this paper the design and efficiency of compiler algorithms that remove ownership overhead in shared-memory multiprocessors with write-invalidate protocols. These algorithms detect loads followed by stores to the same address. Such loads are marked and constitute a hint to the cache to obtain an exclusive copy of the block. We consider three algorithms where the first one focuses on load-store sequences within each basic block of code and the other two analyse the existence of load-store sequences across basic blocks at the intra-procedural level. Since the dataflow analysis we adopt is a trivial variation of live-variable analysis, the algorithms are easily incorporated into a compiler. Through detailed simulations of a cache-coherent NUMA architecture using five scientific parallel benchmark programs, we find that the algorithms are capable of removing over 95% of the separate ownership acquisitions. Moreover, we also find that even the simplest algorithm is comparable in efficiency with previously proposed hardware-based adaptive cache coherence protocols to attack the same problem.