gebhart/patrepeval huggingface dataset:
Diffusion of Simple Liquids in Porous Sol-Gel Glass (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiffusion of Simple Liquids in Porous Sol-Gel GlassN. Koone, Y. Shao, and T. W. ZerdaCite this: J. Phys. Chem. 1995, 99, 46, 16976–16981Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/j100046a025https://doi.org/10.1021/j100046a025research-articleACS PublicationsRequest reuse permissionsArticle Views457Altmetric-Citations58LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Antifouling marine natural products (2010)

Covering: 2004 to June 2010
Community-acquired respiratory syncytial virus and parainfluenza virus infections after hematopoietic stem cell transplantation: The Fred Hutchinson Cancer Research Center experience (2001)

Community respiratory viruses (CRVs) are an important cause of morbidity and mortality among recipients of hematopoietic stem cell transplants (HSCT). At the Fred Hutchinson Cancer Research Center, respiratory syncytial virus (RSV) and parainfluenza virus (PIV) infections in HSCT recipients have been studied intensively for more than a decade. Over time, mortality from these infections has declined as the approach to diagnosis has become more aggressive and more stringent preventive measures have been instituted. However, mortality among HSCT recipients with RSV or PIV pneumonia remains high. Uncontrolled studies at our center suggest that prompt therapy with aerosolized ribavirin has reduced mortality from RSV pneumonia but does not appear to affect the course of established PIV pneumonia. Two controlled clinical trials of ribavirin therapy for RSV infection in HSCT recipients are in progress.
A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies (2016)

GLPG0187 was well tolerated with a dose-proportional PK profile upon continuous infusion. No formal maximal tolerated dose could be established. GLPG0187 showed signs of target engagement with a favourable toxicity profile. However, continuous infusion of GLPG0187 failed to show signs of monotherapy efficacy.
Pyrrone - A new class of aromatic step-ladder and ladder polymers. (1965)

Aromatic/heterocyclic polymers from tetraamines reaction with tetraacids at room temperature, developing potential for aerospace application
Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury - Randomized Prospective Trial (2013)

ClinicalTrials.gov NCT00715052.
A Study of Angiotensin II Pressor Response throughout Primigravid Pregnancy (1973)

The present study was designed to ascertain sequentially the pressor response to angiotensin II in young primigravid patients throughout pregnancy in order a) to define when in pregnancy resistance to the pressor effects of angiotensin II develops; b) to define the physiologic sequence of events leading to this resistance; and c) to ascertain whether sensitivity to infused angiotensin II could be detected before the onset of clinical signs of pregnancy-induced hypertension. With this prospective approach, two separate groups of patients were defined. The first group of patients remained normal throughout pregnancy. The second group consisted of those patients who, while clinically normotensive during the initial phase of the study, ultimately developed hypertension of pregnancy.192 patients were studied; of these, 120 patients remained normotensive and 72 developed pregnancy-induced hypertension. In both groups, vascular resistance to infused angiotensin II (more than 8 ng/kg/min required to elicit a pressor response of 20 mm Hg in diastolic pressure) was demonstrated as early as the 10th wk of pregnancy. In the group that remained normotensive, maximum mean vascular resistance occurred at 18-30 wk of pregnancy, (mean pressor dose required being 13.5 to 14.9 ng/kg/min). In those subjects who developed pregnancy-induced hypertension, the mean maximum dose required was 12.9 ng/kg/min, which was observed at the 18th wk of pregnancy. By the 22nd wk there was a clear separation of the two groups, with the mean dose requirement of the subjects destined to develop hypertension being progressively less than that of those who remained normal. The difference between the two groups became significant (P < 0.01) by 23-26 wk of pregnancy. Among patients requiring more than 8 ng/kg/min on one or more tests done between wk 28-32, 91% remained normotensive. Conversely, during the same time period among patients requiring less than 8 ng/kg/min, on at least one occasion, 90% developed pregnancy-induced hypertension.
Pentavalent pneumococcal oligosaccharide conjugate vaccine PncCRM is well-tolerated and able to induce an antibody response in infants (1996)

Pneumococcal oligosaccharide-CRM197 conjugate vaccine is able to induce an IgG serum response in infants and anti-pneumococcal antibody concentrations were significantly higher than in controls of same age.
New state assignment algorithms for finite state machines using look ahead (2002)

Three heuristic algorithms for state assignments in the design of synchronous finite state machines (FSMs) have been developed. The objective is to minimize the estimated area of the implemented FSM. The first method, called look ahead for states (LAS), chooses a state to be assigned and then selects a (locally) optimal code for the state. The second method, called look ahead for codes (LAC), chooses a code and then selects a (locally) optimal state for the code. The third method, called look ahead for states and codes (LASC), considers concurrently states and codes. Experimental results show that the proposed algorithms generate better results on the average than those of several previous approaches.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Epitope Mapping of Monoclonal Antibodies against<i>Bordetella pertussis</i>Adenylate Cyclase Toxin (1999)

Adenylate cyclase (AC) toxin from Bordetella pertussis is a 177-kDa repeats-in-toxin (RTX) family protein that consists of four principal domains; the catalytic domain, the hydrophobic domain, the glycine/aspartate-rich repeat domain, and the secretion signal domain. Epitope mapping of 12 monoclonal antibodies (MAbs) directed against AC toxin was conducted to identify regions important for the functional activities of this toxin. A previously developed panel of in-frame deletion mutants of AC toxin was used to localize MAb-specific epitopes on the toxin. The epitopes of these 12 MAbs were located throughout the toxin molecule, recognizing all major domains. Two MAbs recognized a single epitope on the distal portion of the catalytic domain, two reacted with the C-terminal 217 amino acids, one bound to the hydrophobic domain, and one bound to either the hydrophobic domain or the functionally unidentified region adjacent to it. The remaining six MAbs recognized the glycine/aspartate-rich repeat region. To localize these six MAbs, different peptides derived from the repeat region were constructed. Two of the six MAbs appeared to react with the repetitive motif and exhibited cross-reactivity with Escherichia coli hemolysin. The remaining four MAbs appeared to interact with unique epitopes within the repeat region. To evaluate the roles of these epitopes on toxin function, each MAb was screened for its effect on intoxication (cyclic AMP accumulation) and hemolytic activity. The two MAbs recognizing the distal portion of the catalytic domain blocked intoxication of Jurkat cells by AC toxin but had no effect on hemolysis. On the other hand, a MAb directed against a portion of the repeat region caused partial inhibition of AC toxin-induced hemolysis without affecting intoxication. In addition, the MAb recognizing either the hydrophobic domain or the unidentified region adjacent to it inhibited both intoxication and hemolytic activity of AC toxin. These findings extend our understanding of the regions necessary for the complex events required for the biological activities of AC toxin and provide a set of reagents for further study of this novel virulence factor.
Management of premature rupture of membranes and unfavorable cervix in term pregnancy. (1984)

One hundred thirty-four indigent patients at term who had premature rupture of membranes and a cervix unfavorable for induction of labor (80% effacement or less, 2 cm dilation or less) were randomized to compare expectant with intervention management. Women with any medical or obstetric condition warranting immediate intervention were excluded from the study. Patients treated expectantly were placed at bed rest and observed for labor or infection. Patients managed by intervention were given oxytocin if labor did not ensue within 12 hours of rupture of the membranes. Patients in the intervention protocol had longer labor (P less than .02) and a higher incidence of both cesarean delivery (P less than .05) and intraamniotic infection (P less than .05). There was only one case of proven neonatal sepsis, and this occurred in a patient managed by induction of labor. There was no statistically significant difference between groups in mean length of maternal hospitalization.
Resolution of water in crude oil emulsion by some novel aromatic amine polyesters (2015)

In this work, three aromatic amines (p-toluidine, p-nitroaniline and p-chloroaniline) were chosen as bases for the repatriation of some nonionic polyesters. These amines were ethoxylated with different total number of ethylene oxide units 6, 12, 18. The prepared ethoxylated amine diols were polyesterified with maleic anhydride and polypropylene oxide polyethylene oxide block copolymers in polyesterification reaction. The demulsification efficiency of these demulsifiers was investigated using the bottle test. The effects of the molecular weight, concentration, asphaltene content, water content, Hydrophile Lipophile Balance (HLB) and temperature on the demulsification efficiency were investigated. The surface active properties were correlated with their demulsification efficiency. It was found that, NAE18D gave the best result in the demulsification process. The demulsification efficiency was discussed on the light of surface active properties, interfacial tension and the factors affecting the demulsification. The surface-active properties of the prepared demulsifiers were measured at 60 °C.
A Study of Students’ Perception on The Use Facebook Group in Improving Writing (2019)

This study attempts to know the students’ perception on a Facebook group in improving writing skill on the tenth grade of SMA 5 Kendari that focus on enhancing students writing performance level and the brainstorm ideas at the pre-writing stage. Also, to find out how Facebook influence the students’ affective domain. The researcher employed mix method design with questionnaire as instrument to collect data from 36 students. The data was analyzed by calculating the frequency distribution of Likert scale. The result reveals there was positive perception among students about applying Facebook Group in improving writing. Particularly, Respondent (89.7%) spell – check feature helps students to avoid the error spelling and (91.6) student feel motivated when they got “like” from their friends. It is suggested that future research to investigate the teacher and students’ problem in applying Facebook. In addition, the future study researcher may investigate the use Facebook Group in another skill of English. Lastly, the future study may investigation the use other SNS not only Facebook but it can be Path, Twitter, or Instagram. Keywords: Facebook Group, Perception, Writing
Lack of transmission of H5N1 avian–human reassortant influenza viruses in a ferret model (2006)

Avian influenza A H5N1 viruses continue to spread globally among birds, resulting in occasional transmission of virus from infected poultry to humans. Probable human-to-human transmission has been documented rarely, but H5N1 viruses have not yet acquired the ability to transmit efficiently among humans, an essential property of a pandemic virus. The pandemics of 1957 and 1968 were caused by avian-human reassortant influenza viruses that had acquired human virus-like receptor binding properties. However, the relative contribution of human internal protein genes or other molecular changes to the efficient transmission of influenza viruses among humans remains poorly understood. Here, we report on a comparative ferret model that parallels the efficient transmission of H3N2 human viruses and the poor transmission of H5N1 avian viruses in humans. In this model, an H3N2 reassortant virus with avian virus internal protein genes exhibited efficient replication but inefficient transmission, whereas H5N1 reassortant viruses with four or six human virus internal protein genes exhibited reduced replication and no transmission. These findings indicate that the human virus H3N2 surface protein genes alone did not confer efficient transmissibility and that acquisition of human virus internal protein genes alone was insufficient for this 1997 H5N1 virus to develop pandemic capabilities, even after serial passages in a mammalian host. These results highlight the complexity of the genetic basis of influenza virus transmissibility and suggest that H5N1 viruses may require further adaptation to acquire this essential pandemic trait.
Epilation of hair‐Bearing urethral grafts utilizing the neodymium: YAG surgical laser (1990)

Non-hair-bearing skin should be utilized when grafting is necessary in carrying out urethroplasty for stricture or hypospadius repair. Occasionally this is not possible, or hair-bearing skin is used inadvertently. Traditionally electrocoagulation has been the method used for epilation when intraluminal hair has become a problem, such as interfering with flow, being foci for recurring urinary tract infection, or acting as a nidus for calculus formation. Electrocautery is also used at the time of grafting in an attempt to prevent the growth of hair when hair-bearing skin is utilized. Unfortunately, because of lack of penetration, the hair follicles are not destroyed and the epilating procedure fails or is only partially successful. The neodymium: YAG (Nd:YAG) surgical laser can photocoagulate tissue to a depth up to 5.0 mm and thus has the ability to destroy hair follicles. We report three cases presenting with clinical problems directly related to hair-bearing urethral grafts successfully treated by Nd:YAG epilation.
Synthesis of medium-sized ring ethers from thionolactones. Applications to polyether synthesis (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of medium-sized ring ethers from thionolactones. Applications to polyether synthesisK. C. Nicolaou, D. G. McGarry, P. K. Somers, B. H. Kim, W. W. Ogilvie, G. Yiannikouros, C. V. C. Prasad, C. A. Veale, and R. R. HarkCite this: J. Am. Chem. Soc. 1990, 112, 17, 6263–6276Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/ja00173a013https://doi.org/10.1021/ja00173a013research-articleACS PublicationsRequest reuse permissionsArticle Views1179Altmetric-Citations108LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Evidence that the major cell surface glycoprotein of the TA3-Ha carcinoma contains the Vicia graminea receptor sites (1975)

The Vicia graminea lectin receptor of the nonstrain-specific TA3-Ha mammary carcinoma ascites cell of the strain A mouse was shown to be predominantly or exclusively on a large mucin-type surface glycoprotein. TA3-Ha cells adsorbed the lectin in amounts equivalent to 5-9 mg of this glycoprotein/10-9 cells, which was 100-400 times greater than by the strain-specific TA3-St cell, employed as a control. Release of sialic acid by incubation with neuraminidase increased the adsorptivity of the TA3-Ha cell three to fourfold and of the TA3-St cell six- to ten fold. Proteolysis of TA3-Ha cells released into the supernatant solutions approximately the same amount of inhibitory activity, equivalent to approximately 5 mg of the glycoprotein and only 10 per cent of the original adsorptivity remained on the cells. By contrast, TA3-St cells released no detectable inhibitory activity into the medium when subjected to similar proteolysis, even after neuraminidase treatment. Upon fractionation of released material on gel columns, high-molecular weight material and activity were found in the same fractions, but purified samples differed significantly in specific activity and carbohydrate composition. Heterogeneity in the carbohydrate moieties of the macromolecules was further demonstrated by incubation of these samples with neuraminidase, which enhanced their inhibitory activities from two- to tenfold.
Radiation dose escalation for localized prostate cancer (2009)

The data from the current study indicate that radiation dose escalation improved the bNED rate for the intermediate-risk group. IMRT caused less acute and late GU toxicity than BRT or EBRT + BRT.
Molecular drug targets and structure based drug design: A holistic approach (2006)

Access to the complete human genome sequence as well as to the complete sequences of pathogenic organisms provides information that can result in an avalanche of therapeutic targets. Structure-based design is one of the first techniques to be used in drug design. Structure based design refers specifically to finding and complementing the 3D structure (binding and/or active site) of a target molecule such as a receptor protein. The aim of this review is to give an outline of studies in the field of structure based drug design that has helped in the discovery process of new drugs. The emphasis will be on comparative/homology modeling.
Results (1976)

We have implemented a demonstration system to test out many of these ideas. It works on a subset of SAIL which includes LISTS and SETS. It does not fully handle triples. All of the phases up to the user interrogation phase (monitoring, static analysis) process the operations on triples; only the interrogation and selection phase and final compiler would have to be modified. Also, of course, the library of primitive operations on associations (which has only been partially implemented) would have to be completed as well as analyzed.KeywordsHash TableCore SizeAutomatic SelectionDefault RepresentationPrimitive OperationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Priming of human myeloid leukemic cell lines HL-60 and U-937 with retinoic acid for differentiation effects of cyclic adenosine 3':5'-monophosphate-inducing agents and a T-lymphocyte-derived differentiation factor. (1982)

The human cell lines HL-60 (acute promyelocytic leukemia) and U-937 (histiocytic monoblast-like lymphoma) differentiate to functionally mature cells by incubation with retinoic acid (RA). This differentiation is potentiated by agents known to increase intracellular cyclic adenosine 3':5'-monophosphate (cAMP) levels. The present study shows that these cells can be primed for differentiation by treatment for approximately one day with RA followed by exposure to a cAMP-inducing agent. The reverse sequence was ineffective. Thus, HL-60 could be primed by incubation for less than 20 hr with 10 nM RA to respond by differentiation to the addition of 10 nM prostaglandin E2 or 1 nM cholera toxin, whereas 10 nM RA alone was almost inactive. RA-primed HL-60 also responded with differentiation to a concentration of T-lymphocyte-derived differentiation-inducing factor which alone was inactive. U-937 primed by incubation for 24 hr with 100 nM RA responded to cAMP-inducing agents and differentiation-inducing factor, which alone were inactive on this cell line. Priming of these cell lines does not depend on the normal rate of protein synthesis, as it occurs even better in the presence of a concentration of cycloheximide that inhibits growth completely, suggesting that a decrease in synthesis of some protein(s) favors RA-induced differentiation. Cycloheximide alone produced some priming of HL-60 but not of U-937. HL-60, but not U-937, primed with RA responded to adenosine triphosphate and other nucleoside triphosphates, consistent with the notion that modulation of the RA effect may be mediated through protein kinase activity at the plasma membrane. The finding that myeloid cell lines, like HL-60 and U-937, blocked at a late stage of maturation can be primed by RA to respond to cAMP-inducing agents and differentiation-inducing factor may improve our understanding of the arrest in maturation typical of some forms of leukemia.
Online Multi-person Tracking by Tracker Hierarchy (2012)

Tracking-by-detection is a widely used paradigm for multi-person tracking but is affected by variations in crowd density, obstacles in the scene, varying illumination, human pose variation, scale changes, etc. We propose an improved tracking-by-detection framework for multi-person tracking where the appearance model is formulated as a template ensemble updated online given detections provided by a pedestrian detector. We employ a hierarchy of trackers to select the most effective tracking strategy and an algorithm to adapt the conditions for trackers' initialization and termination. Our formulation is online and does not require calibration information. In experiments with four pedestrian tracking benchmark datasets, our formulation attains accuracy that is comparable to, or better than, the state-of-the-art pedestrian trackers that must exploit calibration information and operate offline.
Freestanding Terahertz Metamaterials Fabricated by Laser Beam Machining (2015)

We demonstrate freestanding terahertz metamaterials, fabricated by laser-beam machining of commercial Aluminum-foil. This method allows for cost-efficient and rapid prototyping. Low insertion losses and outstanding transmission characteristics render the samples as high performance filters.