gebhart/patrepeval huggingface dataset:
Yarn Evenness in Open-End Spinning (1974)

Open-end yarn is said to have a better evenness than ring yarn, but the truth of this statement depends on the error wavelength. It is shown that errors are reduced when the error wavelength in the yarn is less than the circumference of the collecting surface. In practice the main advantages in open-end spinning as far as evenness is concerned derive from the suppression or avoidance of drafting waves and the manufacture of large packages.
Radioimmunoscintigraphy of colon cancer with iodine-131-labeled B72.3 monoclonal antibody. (1988)

The monoclonal antibody B72.3 is a murine IgG1 that is reactive with a wide range of carcinomas while demonstrating little or no reactivity to normal adult tissues. We have shown (27) quantitative analyses demonstrating selective targeting of [131I]B72.3 IgG to metastatic colorectal cancer. We have also shown (28) that (a) B72.3 localization in metastases correlated with the percentage of tumor cells in the biopsy specimen; (b) B72.3 could localize in carcinomas of various degrees of differentiation with best localization in well-differentiated tumors and (c) [131I]B72.3 could penetrate tumor masses, as determined by autoradiographic studies. We report here the various parameters effecting radioimmunoscintigraphy with [131I]B72.3 IgG. Sixteen of 35 patients with colorectal carcinoma had positive scans (without blood-pool subtraction). High circulating TAG-72 antigen levels correlated with positive scans. No dose dependent differences were seen in biodistribution or tumor imaging. The plasma clearance and urinary excretion of [131I]B72.3 and [125I]BL-3 (nonspecific control) were not significantly different. No toxicity was noted. Approximately one-half of patients developed human anti-mouse immune response.
To infinity and beyond: time-warped network emulation (2006)

The goal of this work is to subject unmodified applications running on commodity operating systems and stock hardware to network speeds orders of magnitude faster than available at any given point in time. This paper describes our approach to time dilation, atechnique to uniformly and accurately slow the passage of time from the perspective of an operating system by a specified factor. As a side effect, physical devices— including the network—appear relatively faster to both applications and operating systems. Both qualitative and statistical evaluations indicate our prototype implementation is accurate across several orders of magnitude. We demonstrate time dilation’s utility by conducting highbandwidth head-to-head TCP stack comparisons and application evaluation. 1
Review: Effects of Inlet Conditions on Conical-Diffuser Performance (1981)

The available experimental evidence of the effects of inlet conditions on the performance of conical diffusers with a free discharge is reviewed. The effects of inlet boundary layer thickness blockage, inlet shape parameter, turbulence, and Reynolds number are discussed. It is shown that many of the inconsistencies between different sources of data are the result of nonturbulent approach flows. Graphs are presented as guidelines for diffuser design.
A rate 16/17 punctured MTR block code (2003)

This paper presents a rate 16/17 "punctured" time varying maximum transition run (PMTR) block code. It is not possible to achieve a rate 16/17 or higher TMTR block code which completely suppresses the minimum distance error event. However, it is in general, possible to make a tradeoff between obtaining higher code rates and coding gain by puncturing; the space of codewords and limiting the extent to which the minimum distance error event is suppressed. As an example, we obtain a rate 16/17 block code where the minimum distance error event is supported in only 6 out of the 17 possible codeword locations. An implementation of the code is presented and simulation results examining the performance benefits under different conditions are also presented.
Comparative Studies of Various Molecular Species in<i>Aspergillus niger</i>Glucoamylase (1988)

A commercial preparation of glucoamylase from Aspergillus niger consisted of at least six species (A-II ~ IV and B-I ~ III), five forms of which were fully characterized. They were apparently different in molecular weight, sedimentation constant (s20,w), isoelectric point (pI), chemical composition, kinetic parameters (k0, molecular activity; kint, intrinsic rate constant), and other enzymatic properties. When compared with enzymological characteristics as well as serological ones, B-I was found to be a peculiar enzyme among them. Furthermore, A-II was significantly discriminated from the other enzymes in respect of molecular weight and composition of amino acid, suggesting that A-II might be the product of transcription of a different DNA site.
The ethyl modification and characterization of SBA-15 mesoporous materials (2005)

Organic groups was successfully grafted into the pore of SBA-15 mesoporous sieve with ethanetriethoxy silane as the coupling agent and the inorganic/organic composite mesoporous materials C_2H_5-SBA-15 synthesized was characerized by SAXRD, nitrogen adsorption-desorption, elemental analysis, FT-IR and titration.The results show that ether was grafted into the pore of SBA-15, C_2H_5-SBA-15 synthesized still retain the ordered mesoporous structure. Due to the introduce of the nonpolar group ethyl, the composite material has high hydrophobicity.
Diagnosis of spontaneous bacterial peritonitis in children by reagent strips. (2013)

This study was aimed to evaluate the efficacy of dipstick tests (leukocyte esterase and nitrite) in diagnosis of spontaneous bacterial peritonitis (SBP) in cirrhotic patients. Forty six children with ascites hospitalized between 2009 and 2010 in Children Medical Center were enrolled in this study. Reagent strip assays for leukocyte esterase and nitrite were performed on ascetic fluid and the results were compared to manual cell counting and ascitic fluid culture. SBP was defined as having a polymorphonuclear ascites count of ≥ 250/mm3. Twenty children were female and twenty six were male with mean age of 3±3.9 years. The sensitivity specificity, positive and negative predictive values of the leukocyte esterase reagent strips were all 100%. The sensitivity, specificity, positive and negative predictive value of the nitrite reagent strip test were 100%, 97%, 90% and 100% respectively. Leukocyte esterase reagent strips may provide a rapid, bedside diagnostic test for the diagnosis of SBP.
Trial fabrication of micron sized arm using reversible TiNi alloy thin film actuators (2002)

A micron-sized arm which has large work space and uses reversible TiNi thin film is proposed. The transformation characteristics as analyzed by the DSC method shows that RTiNi can be controlled around 60/spl deg/C. The design method and fabrication process for the arm are described, and the arm was fabricated on silicon wafer. It was shown that micron sized arm using three RTiNi thin films could be fabricated based on the trial fabrication of simple micron sized arm using a RTiNi thin film.
SUNNY: a new algorithm for trust inference in social networks using probabilistic confidence models (2007)

Figure 1: A sample social network with trust values (on a 0-1 scale) as edge labels. In many computing systems, information is produced and processed by many people. Knowing how much a user trusts a source can be very useful for aggregating, filtering, and ordering of information. Furthermore, if trust is used to support decision making, it is important to have an accurate estimate of trust when it is not directly available, as well as a measure of confidence in that estimate. This paper describes a new approach that gives an explicit probabilistic interpretation for confidence in social networks. We describe SUNNY, a new trust inference algorithm that uses a probabilistic sampling technique to estimate our confidence in the trust information from some designated sources. SUNNY computes an estimate of trust based on only those information sources with high confidence estimates. In our experiments, SUNNY produced more accurate trust estimates than the well known trust inference algorithm TIDALTRUST (Golbeck 2005), demonstrating its effectiveness.
Do not share! (2014)

The ubiquity of cameras in today's world has played a key role in the growth of sensing technology and mobile computing. However, on the other hand, it has also raised serious concerns about privacy of people who are photographed, intentionally or unintentionally. The popularity of publishing pictures in social networks adds to the concern that the photographed user has the least control over his/her picture. In this paper, we present the design, implementation and evaluation of "invisible light beacons" where privacy preferences of photographed users are communicated to photographing cameras. Particularly, we explore a design where the beacon transmitters are worn by users on their eye-wear and transmit a privacy code through ON-OFF patterns of light beams from IR LEDs. The beacons are received and decoded by a camera and mapped to different privacy preferences corresponding to that code. Based on the experimental evaluation of thousands of data points using our prototype implementation we show that the detection accuracy of a known privacy code is greater than 98%, and error rate of communicating a random stream of bits over an indoor IR-camera channel is within 7% at packet level and of the order of 10-3 at bit level.
Richard Raxworthy, Independent Oral Historian, and his Oral History Collection in the Mitchell Library, State Library of New South Wales (2007)

A tribute to the work of Richard Raxworthy, who was a life member of the OHAA, and died in December 2003. There are 21 separate entries for his oral history collections archived in the Mitchell Library; notably, these include an interview with Australia's iconic pioneer oral historian Wendy Lowenstein who, sadly, also passed away recently, and for whom obituaries are included in this issue of the OHAA Journal. It is indeed fortunate when an oral historian of renown has also been subject of an interview, and this article draws on the one with Richard that was recorded by his son Julian, and provides insights to his personal history, character and approach to his work. From the many projects that could have been chosen, outlines with examples from two important projects are provided - interviews with builders of the Sydney Harbour Bridge, and Morse code operators.
An economic replacement model with probabilistic asset utilization (2001)

Traditional economic replacement analysis provides asset purchase and sale decisions over a given horizon based on expected purchase, operating, maintenance and salvage costs. As these costs are dependent on asset utilization, a constant or predetermined usage is generally assumed. However, due to randomness in operations, such as customer demand, these expected utilization schedules may not be realized in practice, thus invalidating the replacement schedule. This paper examines the effect of probabilistic asset utilization on replacement decisions through the use of dynamic programming. The solution determines minimum expected cost decisions for each state defined by the asset's age and cumulative utilization in each period. These decisions generalize the definition of the economic life of an asset to include age and cumulative utilization. Assumptions common to replacement analysis allow the state space to grow linearly with time, avoiding dynamic programming's ‘curse of dimensionality’. Examples with time invariant and variant economics are presented and compared to traditional solution procedures
Visual support for porting large code bases (2011)

We present a tool that helps C/C++ developers to estimate the effort and automate software porting. Our tool supports project leaders in planning a porting project by showing where a project must be changed, how many changes are needed, what kinds of changes are needed, and how these interact with the code. For developers, we provide an overview of where a given file must be changed, the structure of that file, and close interaction with typical code editors. To this end, we integrate code querying, program transformation, and software visualization techniques. We illustrate our solution with use-cases on real-world code bases.
Persistent DDT Metabolite p,p'-DDE is a Potent Androgen Receptor Antagonist (1996)

Kelce, William R.; Stone, Christy R.; Laws, Susan C.; Gray, Earl L.; Kemppainen, Jon A.; Wilson, Elizabeth M. Author Information
Regulation of <i>RUNX3</i> Tumor Suppressor Gene Expression in Cutaneous Melanoma (2009)

RUNX3 is down-regulated during melanoma progression and miR-532-5p is a regulatory factor of RUNX3 expression.
Clicking on Things (2010)

Physical objects are being linked to the digital world using multimedia technologies like audiovisual content recognition and large-scale multimedia content-based search.
Effect of Airfoil Aerodynamic Loading on Trailing Edge Noise Sources (2005)

A previous experimental investigation of the broadband self noise radiated by an industrial cambered controlled-diffusion airfoil embedded in an homogeneous flow at low Mach number has been extended to various aerodynamic loadings. The instrumented airfoil is placed at the exit of an open-jet anechoic wind tunnel, with a jet width of about four chord lengths. Sound is measured in the far field at the same time as the statistical properties of the wall-pressure fluctuations close to the trailing edge. A new set of mean wall-pressure data has been collected on this airfoil at a chord Reynolds number of 2.9 x 105, which provides some insight on the Reynolds-number effect. Two previously investigated flow regimes with different statistical behaviors are investigated by changing the angle of attack from 8 to 15 deg. They respectively correspond to the nearly separated boundary layer with vortex shedding at the trailing edge and to the turbulent boundary layer initiated by a leading-edge separation.
Integrated passive components in MCM-Si technology and their applications in RF-systems (2002)

Integrated passive components and their application in RF systems in a silicon-on-silicon multichip technology is presented. In high frequency devices, the main use of passive components is for decoupling purposes, matching networks, LC filters, tank circuits, hybrids, transformers, attenuators and power dividers. In most cases, the design of precise component values and high Q-factors for the inductors and capacitors is necessary, which is a difficult task for integrated components on silicon. General design aspects of passive components with their facilities and restrictions to improve their high frequency behaviour and quality factors are described. In particular, the impact of different substrate resistivities on their performance is pointed out. Test structures on substrates with resistivities of 15 /spl Omega/cm, 2000 /spl Omega/cm and 20000 /spl Omega/cm were therefore manufactured.
Signaling‐sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor (2010)

The thyrotropin receptor [thyroid-stimulating hormone receptor (TSHR)], a G-protein-coupled receptor (GPCR), is endogenously activated by thyrotropin, which binds to the extracellular region of the receptor. We previously identified a low-molecular-weight (LMW) agonist of the TSHR and predicted its allosteric binding pocket within the receptor's transmembrane domain. Because binding of the LMW agonist probably disrupts interactions or leads to formation of new interactions among amino acid residues surrounding the pocket, we tested whether mutation of residues at these positions would lead to constitutive signaling activity. Guided by molecular modeling, we performed site-directed mutagenesis of 24 amino acids in this spatial region, followed by functional characterization of the mutant receptors in terms of expression and signaling, measured as cAMP accumulation. We found that mutations V421I, Y466A, T501A, L587V, M637C, M637W, S641A, Y643F, L645V, and Y667A located in several helices exhibit constitutive activity. Of note is mutation M637W at position 6.48 in transmembrane helix 6, which has a significant effect on the interaction of the receptor with the LMW agonist. In summary, we found that a high proportion of residues in several helices surrounding the allosteric binding site of LMW ligands in the TSHR when mutated lead to constitutively active receptors. Our findings of signaling-sensitive residues in this region of the transmembrane bundle may be of general importance as this domain appears to be evolutionarily retained among GPCRs.
Squamous change in bladder cancer and its relevance to understanding clonal evolution in development of bladder cancer. (1998)

Using conventional morphological assessment, squamous change in bladder epithelium has been observed in 73% of bilharzial associated squamous cancers but only 28% of pure transitional cancers. However, more detailed studies of patients with TCC suggest that the latter figure may be an underestimate, since in one series it was reported to be more than 50%. The most significant risk factor for development of squamous carcinoma in the bladder is chronic persistent bacterial cystitis, although in the areas of the world where bilharzia is endemic this infestation also increases the risk of both squamous bladder cancer and chronic bacterial cystitis. Although it is clear that carcinogens are involved as co-factors in transformation from squamous metaplasia to cancer, the fact that in Zimbabwe one author has observed that TCC is more frequent in whites than squamous cancer is in bilharzia infected blacks is evidence that other unidentified risk factors are involved. This is increasing evidence for involvement of HPV subtypes in cervix, oropharynx and lung cancer. As all three of these tumours are associated with squamous metaplasia, there could be a case for investigation of bladder squamous tumours for HPV involvement. This is particularly so given the observation of the "hit and run" type of transient infection in cattle that develop BPV associated tumours and the tenfold difference (30% vs 3%) in frequency of HPV detection in squamous skin tumours developing in immunosuppressed individuals compared with those arising spontaneously. With new technology for cytological screening techniques using dot ELISA and evidence of differences in TP53 mutations that support the involvement of nitrous oxide, it is clear that there is more to learn from study of this tumour type that may be of general interest in understanding the clonal development of cancer.
Quality management framework for public management decision making (2012)

Purpose This paper aims to explore the practice of quality management framework as a strategic tool for public management. Design/methodology/approach The paper starts with a basic process‐based model; it then enhances the model with the quality management principles for continuous improvement. With identification of concerned factors from the literature, it examines their usefulness in the quality management system. Findings An empirical analysis on the framework identifies eight factors: factual approach to decision making, use of quality tools, customer focus, leadership, involvement of people, process approach, mutually beneficial supplier partnership and internal results. The framework shows that leadership and customer focus are much more important than previously anticipated for successful implementation of quality management system. Research limitations/implications Managers in public organizations must realize that all high performance organizations, whether private or public, are by principle customer‐driven. In addition, it is imperative for them to enhance their leadership as it is essential for effective quality improvement. Originality/value While the effect of adopting a quality management system on organizational performance has been well documented, the underlying mechanism about how the system works has yet to be empirically identified. This paper contributes to the literature by addressing such a gap and presenting a causal model for quality management principles.
Fate of amnion‐derived stem cells transplanted to the fetal rat brain: migration, survival and differentiation (2008)

We have recently characterized a stem cell population isolated from the rodent amniotic membrane termed amnion-derived stem cells (ADSCs). In vitro ADSCs differentiate into cell types representing all three embryonic layers, including neural cells. In this study we evaluated the neuroectodermal potential of ADSCs in vivo after in utero transplantation into the developing rat brain. A clonal line of green fluorescent protein-expressing ADSCs were infused into the telencephalic ventricles of the developing embryonic day 15.5 rat brain. At E17.5 donor cells existed primarily as spheres in the ventricles with subsets fused to the ventricular walls, suggesting a mode of entry into the brain parenchyma. By E21.5 green fluorescent protein (GFP) ADSCs migrated to a number of brain regions. Examination at postnatal time points revealed that donor ADSCs expressed vimentin and nestin. Subsets of transplanted ADSCs attained neuronal morphologies, although there was no immunohistochemical evidence of neural or glial differentiation. Some donor cells migrated around blood vessels and differentiated into putative endothelial cells. Donor ADSCs transplanted in utero were present in recipients into adulthood with no evidence of immunological rejection or tumour formation. Long-term survival may suggest utility in the treatment of disorders where differentiation to a neural cell type is not required for clinical benefit.
Predisposition to abacavir hypersensitivity conferred by<i>HLA-B</i>*<i>5701</i>and a haplotypic<i>Hsp70-Hom</i>variant (2004)

Susceptibility to a clinically significant drug hypersensitivity syndrome associated with abacavir use seems to have a strong genetic component. We have previously shown that the presence of HLA-B*5701 strongly predicts abacavir hypersensitivity and have identified a potential susceptibility locus within a 300-kb region between the MEGT1 and C4A6 loci in the central MHC. We now report the results of fine recombinant genetic mapping in an expanded patient population of 248 consecutive, fully ascertained, abacavir-exposed individuals in the Western Australian HIV Cohort Study, in which 18 cases of definite abacavir hypersensitivity (7.3%) and 230 tolerant controls were identified. Haplotype mapping within patients with allelic markers of the 57.1 ancestral haplotype suggests a susceptibility locus within the 14-kb Hsp70 gene cluster. HLA-B*5701 was present in 94.4% of hypersensitive cases compared with 1.7% of controls (odds ratio, 960; P < 0.00001). A haplotypic nonsynonymous polymorphism of Hsp70-Hom (HspA1L, resulting from the substitution of residue M493T in the peptide-binding subunit) was found in combination with HLA-B*5701 in 94.4% of hypersensitive cases and 0.4% of controls (odds ratio, 3,893; P < 0.00001). Individuals with abacavir hypersensitivity demonstrated increased monocyte tumor necrosis factor expression in response to ex vivo abacavir stimulation, which was abrogated with CD8(+) T cell depletion. These data indicate that the concurrence of HLA-B*5701 and Hsp70-Hom M493T alleles is necessary for the development of abacavir hypersensitivity, which is likely to be mediated by an HLA-B*5701-restricted immune response to abacavir.