gebhart/patrepeval huggingface dataset:
Distributed charging of PHEVs in a smart grid (2011)

This paper proposes a novel charging method for plug-in hybrid electric vehicles (PHEVs) in a smart grid. It is based on a distributed and autonomous framework where users or PHEVs can adapt their charging rates according to their preferences. In particular, we borrow the concept of congestion pricing in Internet traffic control and show that pricing information is very useful to regulate user demand and hence balance network load. User preference is modeled as a willingness to pay parameter which will impact the price and charging rate. Simulation results are presented to demonstrate the dynamic behavior of the algorithm and impact of different parameters on system performance.
Synthesis of dihydrodiol and other derivatives of benz[c]acridine (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of dihydrodiol and other derivatives of benz[c]acridineRoland E. Lehr and Subodh KumarCite this: J. Org. Chem. 1981, 46, 18, 3675–3681Publication Date (Print):August 1, 1981Publication History Published online1 May 2002Published inissue 1 August 1981https://pubs.acs.org/doi/10.1021/jo00331a019https://doi.org/10.1021/jo00331a019research-articleACS PublicationsRequest reuse permissionsArticle Views347Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
C4-Mediated Inhibition of Immune Precipitation and Differences in Inhibitory Action of Genetic Variants, C4A3 and C4B1 (1988)

The inhibition of immune precipitation is mediated by the classical complement pathway. We report here that the rate of precipitate formation depends on the genetic form of human C4 present during immune precipitation. C4A3 is more effective than C4B1 in its capacity to inhibit the rate of immune precipitate formation in serum and in serum-free reaction mixtures containing C1 and C4. Immune precipitates form within seconds after antigen is mixed with antibody, and the activation of the classical pathway is known to occur within seconds after C1 binds to antibody molecules. The covalent deposition of C4b on immune complexes is an essential step in the inhibition of immune precipitate formation, and if any of the reactions that lead to covalent C4b deposition become limiting, the rate of immune precipitation could exceed the complement system's inhibitory capacity. Hence, the inhibition of this rate may be an important function underlying the complement-mediated processing of immune complexes, and a decreased ability of the complement system to mediate this process in the presence of C4B1, in contrast to C4A3, could explain, at least in part, the association between the C4A-null phenotype and autoimmune diseases such as systemic lupus erythematosus.
Boosting Classifiers for Music Genre Classification (2006)

This paper investigates discriminative boosting of classifiers to improve the automatic music genre classification performance. Two classifier structures, boosting of the Gaussian mixture model based classifiers and classifiers that are using the intergenre similarity information, are proposed. The first classifier structure presents a novel extension to the maximum-likelihood based training of the Gaussian mixtures to integrate GMM classifier into boosting architecture. In the second classifier structure, the boosting idea is modified to better model the intergenre similarity information over the mis-classified feature population. Once the inter-genre similarities are modeled, elimination of the inter-genre similarities reduces the inter-genre confusion and improves the identification rates. A hierarchical auto-clustering classifier scheme is integrated into the intergenre similarity modeling. Experimental results with promising classification improvements are provided.
A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits. (2002)

We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of Sry from the Y and subsequent insertion of an Sry transgene onto an autosome), so that the determination of testis development occurred independently of the complement of X or Y chromosomes. We compared XX and XY mice with ovaries (females) and XX and XY mice with testes (males). These comparisons allowed us to assess the effect of sex chromosome complement (XX vs XY) independent of gonadal status (testes vs ovaries) on sexually dimorphic neural and behavioral phenotypes. The phenotypes included measures of male copulatory behavior, social exploration behavior, and sexually dimorphic neuroanatomical structures in the septum, hypothalamus, and lumbar spinal cord. Most of the sexually dimorphic phenotypes correlated with the presence of ovaries or testes and therefore reflect the hormonal output of the gonads. We found, however, that both male and female mice with XY sex chromosomes were more masculine than XX mice in the density of vasopressin-immunoreactive fibers in the lateral septum. Moreover, two male groups differing only in the form of their Sry gene showed differences in behavior. The results show that sex chromosome genes contribute directly to the development of a sex difference in the brain.
Efficient Sampling of Electromagnetic Fields via the Adaptive Cross Approximation (2007)

The adaptive cross approximation method is applied to the problem of efficiently sampling an electromagnetic field across two dimensions. The algorithm uses previously collected samples to determine which field samples to take next and reduces the number of samples required to accurately represent the field. In this way the field may be sampled faster than it would have been if it had been raster scanned. This is achieved without significant changes to the sensor hardware.
Detection of <i>Staphylococcus aureus</i> Enterotoxins A to D by Real-Time Fluorescence PCR Assay (2003)

Staphylococcus aureus is one of the most significant pathogens causing nosocomial and community-acquired infections. Among the secreted staphylococcal virulence factors, there is a growing list of enterotoxins which can induce gastroenteric syndrome and toxic shock syndrome. Here, we developed a real-time fluorescence PCR assay (TaqMan PCR) for the detection of genes encoding staphylococcal enterotoxins A, B, C1, and D (SEA, SEB, SEC1, and SED) of S. aureus as well as the mecA gene encoding methicillin resistance and the femB gene as a specific genomic marker for S. aureus. SEA to SED were selected because they are the four classically described enterotoxins of S. aureus and because they were detected by latex agglutination. In order to evaluate the reliability of TaqMan PCR, we investigated 93 isolates of S. aureus derived from patients at our hospital over 5 months and compared the results with data obtained by a commercially available reversed passive latex agglutination assay (SET-RPLA) for these isolates. Thirteen enterotoxin genes were detected by TaqMan PCR; however, no proteins expressed by these genes were detected by SET-RPLA. As a result, more isolates of S. aureus (n = 44) were found positive by TaqMan PCR for one or more enterotoxin genes than by SET-RPLA for the respective proteins expressed by these genes (n = 40). We conclude that TaqMan PCR is more sensitive because it offers the possibility for determining enterotoxins on a genotypic basis. Additionally, the assay allows the parallel detection of genes for SEA to SED and methicillin resistance in S. aureus. Furthermore, real-time PCR is well suited for screening large numbers of samples at the same time, allowing rapid, reliable, efficient, and cost-saving routine laboratory diagnosis.
A Convergence Time Optimization Paradigm for OSPF based Networks Through SDN SPF Protocol Computer Communications and Networks (CCN)/Delay Tolerant Networks (2017)

Distributed routing protocols have been developed extensively in the last couple of decades. But their inflexible and complex behavior have ever been a constraint that makes them inappropriate even for current needs of network. As more and more virtual machines are being added in every network, distributed networks have reached to bottleneck in many aspects. The rise of SDN (Software Defined Networks) has emerged as a potential solution for current and future network requirements. SDN have proved their appropriation than legacy networks in many aspects included with convergence time as a imperative one. This paper provides a comparative analysis based study of convergence time for SDN and an OSPF based legacy network. We have calculated the convergence time of an SDN when there occurs a link update (i.e. network link down/up). Same is calculated for an OSPF based network. Our experimental results show that SDN is far more better choice for large scale networks when compared with OSPF. This time effectiveness turns out to be very considerable when the network is larger and link delays are higher.
Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer (2009)

Full-length CK19 is released by viable epithelial tumor cells, and CK19-RCs might constitute a biologically active subset of breast cancer cells with high metastatic properties.
Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding (2011)

The dengue virus (DENV) envelope (E) protein mediates virus entry into cells via interaction with a range of cell-surface receptor molecules. Cell-surface glycosaminoglycans (GAGs) have been shown to play an early role in this interaction, and charged oligosaccharides such as heparin bind to the E protein. We have examined this interaction using site-directed mutagenesis of a recombinant form of the putative receptor-binding domain III of the DENV-2E protein expressed as an MBP (maltose-binding protein)-fusion protein. Using an ELISA-based GAG-binding assay, cell-based binding analysis and antiviral-activity assays, we have identified two critical residues, K291 and K295, that are involved in GAG interactions. These studies have also demonstrated differential binding between mosquito and human cells.
Initiation of Protein O Glycosylation by the Polypeptide GalNAcT-1 in Vascular Biology and Humoral Immunity (2007)

Core-type protein O glycosylation is initiated by polypeptide N-acetylgalactosamine (GalNAc) transferase (ppGalNAcT) activity and produces the covalent linkage of serine and threonine residues of proteins. More than a dozen ppGalNAcTs operate within multicellular organisms, and they differ with respect to expression patterns and substrate selectivity. These distinctive features imply that each ppGalNAcT may differentially modulate regulatory processes in animal development, physiology, and perhaps disease. We found that ppGalNAcT-1 plays key roles in cell and glycoprotein selective functions that modulate the hematopoietic system. Loss of ppGalNAcT-1 activity in the mouse results in a bleeding disorder which tracks with reduced plasma levels of blood coagulation factors V, VII, VIII, IX, X, and XII. ppGalNAcT-1 further supports leukocyte trafficking and residency in normal homeostatic physiology as well as during inflammatory responses, in part by providing a scaffold for the synthesis of selectin ligands expressed by neutrophils and endothelial cells of peripheral lymph nodes. Animals lacking ppGalNAcT-1 are also markedly impaired in immunoglobulin G production, coincident with increased germinal center B-cell apoptosis and reduced levels of plasma B cells. These findings reveal that the initiation of protein O glycosylation by ppGalNAcT-1 provides a distinctive repertoire of advantageous functions that support vascular responses and humoral immunity.
Development of a Device for Quantifying Hard-to-Cook Phenomenon in Cereal Legumes (1985)

ABSTRACT Aprototype device, EBCoCT (Electronic Bean/Cowpea Cookability Tester), was developed to evaluate the degree of hardness in cooked beans. A Mattson-type plunger-based instrument was modified to electronically indicate the cooked condition of individual seeds in a cooking test of a sample. Several graphical and computer data analysis methods have been discussed to estimate the mean cooking time. The EBCoCT has potential practical applications in evaluating the conditions (storage, environmental and physiological) affecting hard-to-cook phenomenon in cereal legumes
Chemical Composition and Seasonal Variations of Rosemary Oil from Southern Spain (2003)

Abstract The composition of 12 essential oil samples, obtained by steam distillation of twigs of rosemary (Rosmarinus officinalis L.) harvested in four different locations from southern Spain and during three phenological stages, has been analyzed by capillary GC and GC/MS in combination with retention indices. Quantitative data relative to 53 constituents (accounting for 96.7-99.2% of the oils), 12 of which being reported for the first time in Spanish rosemary oil, are described. All samples studied belong to the chemotype α-pinene/l,8-cineole/eamphor, the main and characteristic components being camphor (17.2-34.7%), α-pinene (10.2-21.6%), 1,8-cineole (12.1-14.4%), camphene (5.2-8.6%), borneol (3.2-7.7%), β-pinene (2.3-7.5%), verbenone (2.2-5.8%), β-caryophyllene (1.8-5.1%), limonene (2.0-3.8%), α-terpineol (1.2-2.5%), myrcene (0.9-4.5%), p-cymene (0.2-3.4%), bornyl acetate (0.2-2.3%), linalool (0.3-1.0%) and terpinen-4-ol (0.4-0.9%). The effect of harvest time on the oil production and chemical composition was examined. The highest oil yields (1.6-1.8%) were recorded during the fruiting period (summer). In general, minimum amounts of camphor and maximum amounts of α-pinene were observed in winter. The concentration of 1,8-cineole was almost constant throughout the year, though other oil constituent levels varied randomly with the plant life cycle. Thus, seasonal and geographical variations on the content of representative components allowed to achieve a quality assessment of the rosemary oils and, consequently, to deduce the best period for processing rosemary in the studied area.
Electroformed Nickel Tooling (2001)

Abstract This article describes the factors to be considered while performing electroforming process. The factors include the shape and size of the mold, expected durability of the mold, required delivery time, and manufacture and cost of the necessary mandrel. The article discusses mandrel fabrication by either the use of fiberglass/resins or by the machining of the mandrel directly from computer-aided design data. It provides a comparison of nickel and other tooling materials in terms of coefficients of thermal expansion, thermal cycles for compression molding, and thermal cycles for metal autoclave molds.
Regulated Genomic Instability and Neoplasia in the Lymphoid Lineage (1999)

A DAPTIVE IMMUNITY in mammals depends on the generation of a vast repertoire of Ig and T-cell receptor (TCR) specificities expressed on individual B and T lymphocytes. Antigen receptor diversity is created by the assembly of variable region gene segments by a process of somatic DNA rearrangement
Selective stimulation of the synthesis of an 80,000-dalton protein by calcium ionophores. (1981)

Brief exposure of cultured chicken pectoralis muscle cells to ionomycin or A23187 selectively increases the rate of incorporation of [35S]methionine into an 80,000-dalton protein was also observed upon cell-free translation of poly(A)-enriched RNA isolated from ionomycin-treated, as compared with control, cultures. These observations suggest that ionomycin selectively increases the cellular concentration of mRNA, which codes for the 80,000-dalton protein. The effect is probably mediated through an increase in cytoplasmic [Ca2+] caused by the ionophore. A similar effect of ionomycin was observed in cultured fibroblasts, HeLa cells, mouse LSP cells, and monkey kidney CV1 cells.
Regulation of cGMP-induced relaxation and cGMP-dependent protein kinase in rat myometrium during pregnancy (1998)

Increases in guanosine 3',5'-cyclic monophosphate (cGMP) induced by nitric oxide (NO), nitrovasodilators, and atrial peptides correlate with relaxation of vascular smooth muscle. Relaxation of myometrial smooth muscle by increases in cGMP, however, has required unusually high concentrations of the cyclic nucleotide. We tested the hypothesis that the sensitivity of myometrium to relaxation by cGMP is increased during pregnancy. Aortic smooth muscle was more sensitive to relaxation by cGMP than myometrial tissues, and, contrary to our hypothesis, myometrium from pregnant rats was least sensitive. Although levels of cGMP were elevated after treatment with the NO donor, S-nitroso-N-acetylpenicillamine, relaxation of myometrial tissues obtained from pregnant rats occurred only at extraordinarily high concentrations. The levels of cGMP-dependent protein kinase (PKG) were significantly decreased in myometrium from pregnant rats compared with myometrium from nonpregnant cycling animals or aortic smooth muscle. Administration of estradiol to ovariectomized rats increased myometrial PKG expression, and progesterone antagonized this response. We conclude that 1) myometrial tissues from pregnant rats are not sensitive to relaxation by cGMP and 2) this insensitivity to cGMP is accompanied by progesterone-mediated decreases in the level of PKG expression.
Smith predictor control and internal model control - a tutorial (2003)

This paper is to provide a guide to the time-delay compensation scheme known as Smith predictor control which uses feedback loop for controlling any system. The Smith predictor control was devised to remove the delay effect from the closed-loop design, and is equivalent to IMC in the sense that the delayed behavior of the plant is cancelled by the plant model. The internal model control (IMC) scheme is discussed together to understand the Smith predictor control in terms of newer theoretical concepts. Related topics such as disturbance rejection, /spl Hscr//sub 2/ optimality, stability, robustness, MIMO systems, SISO systems and windup problem are also discussed.
Automating the balanced scorecard – selection criteria to identify appropriate software applications (2003)

The balanced scorecard (BSC) is a management tool that helps to align behavior of all employees to the organization’s strategy. Research suggests that about half of large US firms have already adopted the BSC and many more are considering implementation. Organization‐wide implementation of a BSC requires IT support and numerous software vendors have taken the opportunity to build software solutions to support a BSC implementation. The problem executives face today is that there are over two‐dozen application‐providers to choose from, each of them claiming that their solution offers unique and important features. Selecting the wrong solution can undermine the entire BSC development effort and the credibility of the performance management system. This article addresses the issue of BSC software by (1) explaining why organizations might need software to support their implementation and (2) by developing a framework to assist organizations in this important decision process.
Assessing and testing the Capital Asset Pricing Model (CAPM): a study involving KSE-Pakistan (2012)

The current research study tests the CAPM, (Capital Asset Pricing Model) in Pakistan’s stock market, Karachi Stock Exchange KSE. Capital Asset Pricing Model explains the links present between risk and return in efficient markets. Therefore the current study has focused on the calculation of Beta of ten companies registered on KSE, and actual and expected returns have been compared. The data analysis revealed the limited applicability of CAPM to the KSE, 100-index. Further studies may be conducted to check the applicability of the model, by taking a large sample of companies, especially in Pakistani stock exchanges.
The role of stress concentrations in accelerated creep and sorption-induced physical aging. (2000)

Le fluage accelere dans les milieux humides cycliques est un phenomene curieux etabli depuis pres de 40 ans, mais qui n'offre aucune explication generalement acceptee. Le but de la presente communication est de promouvoir un mecanisme de concentration de contraintes causees par la sorption. Nous demontrons qu'une charge cyclique a plus d'effet qu'une charge moyenne constante, et que la sorption cyclique cree des contraintes localisees. A notre avis, cela suffit a expliquer le fluage accelere. Nous interpretons le vieillissement physique entraine par la sorption comme un phenomene similaire resultant de la sensibilite du fluage a la charge et des contraintes residuelles qui s'accumulent pendant la sorption. Enfin, nous demontrons qu'il y a un type de durcissement resultant de la relaxation rapide des contraintes residuelles lorsqu'un materiau est soumis a une charge.
Direct detection of <i>Streptococcus mutans</i> in human dental plaque by polymerase chain reaction (1996)

Streptococcus mutans is an etiological agent in human dental caries. A method for the detection of S. mutans directly from human dental plaque by polymerase chain reaction has been developed. Oligonucleotide primers specific for a portion of the dextranase gene (dexA) of S. mutans Ingbritt (serotype c) were designed to amplify a 1272-bp DNA fragment by polymerase chain reaction. The present method specifically detected S. mutans (serotypes c, e and f), but none of the other mutans streptococci: S. cricetus (serotype a), S. rattus (serotype b), S. sobrinus (serotypes d and g), and S. downei (serotype h), other gram-positive bacteria (16 strains of 12 species of cocci and 18 strains of 12 species of bacilli) nor gram-negative bacteria (1 strain of 1 species of cocci and 20 strains of 18 species of bacilli). The method was capable of detecting 1 pg of the chromosomal DNA purified from S. mutans Ingbritt and as few as 12 colony-forming units of S. mutans cells. The S. mutans cells in human dental plaque were also directly detected. Seventy clinical isolates of S. mutans isolated from the dental plaque of 8 patients were all positive by the polymerase chain reaction. These results suggest that the dexA polymerase chain reaction is suitable for the specific detection and identification of S. mutans.