gebhart/patrepeval huggingface dataset:
Mucin-Type Glycoproteins as Tumor Markers (1985)

Journal Article Mucin-Type Glycoproteins as Tumor Markers Get access Harry G. Rittenhouse, PhD, Harry G. Rittenhouse, PhD Dept of Experimental Biology, Abbott Diagnostics Division, Abbott Laboratories, North Chicago, IL 60064,. Search for other works by this author on: Oxford Academic PubMed Google Scholar George L. Manderino, PhD, George L. Manderino, PhD Dept of Experimental Biology, Abbott Diagnostics Division, Abbott Laboratories, North Chicago, IL 60064,. Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Michael Hass, PhD G. Michael Hass, PhD Dept of Experimental Biology, Abbott Diagnostics Division, Abbott Laboratories, North Chicago, IL 60064,. Search for other works by this author on: Oxford Academic PubMed Google Scholar Laboratory Medicine, Volume 16, Issue 9, 1 September 1985, Pages 556–560, https://doi.org/10.1093/labmed/16.9.556 Published: 01 September 1985
Measurement of Stress In Very Thin Electrodeposits (1961)

A modified form of the Brenner‐Senderoff contractometer is described. Greater sensitivity is achieved by using jeweled bearings and optical read‐out. The instrument is sensitive enough to yield quantitative stress data in films as thin as 40Aå average thickness. This instrument has been used to study the initial growth of the plating in thin electrodeposited films of nickel and iron‐nickel alloys. Electron micrographs of the films were made to help in interpreting the stress data.
A Cost Effective Method to Create AccurateEngine Performance Maps & Updating the Nebraska Pumping Plant Performance Criteria (2014)

The objective of this paper was to develop a simplified process to create engine performance maps using tractor test data and theoretical modeling techniques. Performance maps for industrial engines can greatly simplify the process of matching engines to their various applications in the most economical way. However, a common performance graph supplied by a manufacturer typically only includes a single performance curve across the range of an engine’s operating speed. The single curve is good for some applications but lacks the needed performance detail at operating conditions other than shown on the performance curve. Extensive testing and resources are required to obtain performance curves at other load conditions. The application of engine performance modeling techniques can save much of the extensive amounts of time and resources required to obtain this data through testing. The results of this research show that tractor performance data can be accurately modeled and adjusted to create engine performance maps. This research also shows how these performance maps can be applied to update the diesel portion of the Nebraska Pumping Plant Performance Criteria (NPPPC). The NPPPC was established and is maintained by the University of Nebraska and has been a useful tool to evaluate irrigation pumping plants’ performance for over 50 years. The NPPPC is a summary of the operating efficiency of all of the components in a pumping plant that create or transmit power. The NPPPC contains criteria for diesel, electricity, gasoline, natural gas, and propane powered pumping plants. The focus of this research was to update the diesel engine portion of the criteria. The results of this research, shows that the diesel portion of the NPPPC should be increased from 3.27 kWh L-1 to 3.36 kWh L-1. As farmers and operators adjust their systems to meet the higher standard they can potentially save $1000s of dollars over the life of an engine. Advisers: William L. Kranz and Roger M. Hoy
Philosophical ethics meets technology: a difficult state of affairs (1997)

Technoscientific developments, especially those which operate on/with human beings, are contributing to their reconfiguration in some new, unprecedented ways. Ethics too is revising radically its own field, probing its own foundations. Sensitive to both movements, bioethics is at a difficult crossroads when much is demanded of it. This paper proposes to contribute to the elucidation of the role of philosophical ethics in the area of bioethics through a critical reading of three of our major contemporary philosophers who have been attempting to meet the challenges of (post)modernity.
A faster and simpler fully dynamic transitive closure (2003)

We obtain a new fully dynamic algorithm for maintaining the transitive closure of a directed graph. Our algorithm maintains the transitive closure matrix in a total running time of O(mn+ (ins + del)·n2), where ins (del) is thenumber of insert (delete) operations performed. Here n is the number of vertices in the graph and m is the initial number of edges in the graph. Obviously, reachability queries canbe answered in constant time. The space required by the algorithm is O(n2). Our algorithm can also support path queries. If v is reachable from u, the algorithm can produce a path from u to v in time proportional to the length of the path. The best previously known algorithm for the problem is due to Demetrescu and Italiano [3]. Their algorithm has total running time of O(n3 + (ins + del).n2). The query time is also constant. We also present an algorithm for directed acyclic graphs (DAGs) with a total running time of O(mn + ins.n2 + del). Our algorithms are obtained by combining somenew ideas with techniques of Italiano [7], King [8], King and Thorup [10] and Frigioni et al. [4]. We also note that ouralgorithms are extremely simple and can be easily implemented.
Active millimeter wave detection of concealed layers of dielectric material (2007)

Extensive work has been published on millimetre wave active and passive detection and imaging of metallic objects concealed under clothing. We propose and demonstrate a technique for revealing the depth as well as the outline of partially transparent objects, which is especially suited to imaging layer materials such as explosives and drugs. The technique uses a focussed and scanned FMCW source, swept through many GHz to reveal this structure. The principle involved is that a parallel sided dielectric slab produces reflections at both its upper and lower surfaces, acting as a Fabry-Perot interferometer. This produces a pattern of alternating reflected peaks and troughs in frequency space. Fourier or Burg transforming this pattern into z-space generates a peak at the thickness of the irradiated sample. It could be argued that though such a technique may work for single uniform slabs of dielectric material, it will give results of little or no significance when the sample both scatters the incident radiation and gives erratic reflectivities due to its non-uniform thickness and permittivity . We show results for a variety of materials such as explosive simulants, powder and drugs, both alone and concealed under clothing or in a rucksack, which display strongly directional reflectivities at millimeter wavelengths, and whose location is well displayed by a varying thickness parameter as the millimetre beam is scanned across the target. With this system we find that samples can easily be detected at standoff distances of at least 4.6m.
CpxP, a Stress-Combative Member of the Cpx Regulon (1998)

The CpxA/R two-component signal transduction system of Escherichia coli can combat a variety of extracytoplasmic protein-mediated toxicities. The Cpx system performs this function, in part, by increasing the synthesis of the periplasmic protease, DegP. However, other factors are also employed by the Cpx system for this stress-combative function. In an effort to identify these remaining factors, we screened a collection of random lacZ operon fusions for those fusions whose transcription is regulated by CpxA/R. Through this approach, we have identified a new locus, cpxP, whose transcription is stimulated by activation of the Cpx pathway. cpxP specifies a periplasmic protein that can combat the lethal phenotype associated with the synthesis of a toxic envelope protein. In addition, we show that cpxP transcription is strongly induced by alkaline pH in a CpxA-dependent manner and that cpxP and cpx mutant strains display hypersensitivity to growth in alkaline conditions.
Investigation of the apoptotic way induced by digallic acid in human lymphoblastoid TK6 cells (2012)

In summary, DGA exhibited an apoptosis inductor effect in TK6 cells revealing thus its potential as a cancer-preventive agent.
Quality of Service (2004)

This chapter examines techniques developed to support Internet Quality of Service (QoS), which are adopted as the basis for 3GPP and 3GPP2 QoS management. It also discusses the architectures and mechanisms specified by 3GPP and 3GPP2 for QoS management.
Experimental Studies in Speaker Verification, Using an Adaptive System (1966)

This paper describes an investigation of the capability of a two-level adaptive linear threshold element (LTE) system to perform speaker discriminations. The study also includes an investigation of discriminating a speaker from an unknown population. The problem has been confined to the verification of an utterance as that of an expected informant. The environment of the experiments is discussed, and the experimental system is described. At the first level LTE, four different kinds of training have been developed for effective transformation and data reduction. At the second-level LTE, different training conditions and different decision processes are investigated and evaluated. Over 90% accuracy is obtained in separating a known speaker from impostors.
Molecular changes in the postmortem parkinsonian brain (2016)

Parkinson disease (PD) is the second most common neurodegenerative disease after Alzheimer disease. Although PD has a relatively narrow clinical phenotype, it has become clear that its etiological basis is broad. Post-mortem brain analysis, despite its limitations, has provided invaluable insights into relevant pathogenic pathways including mitochondrial dysfunction, oxidative stress and protein homeostasis dysregulation. Identification of the genetic causes of PD followed the discovery of these abnormalities, and reinforced the importance of the biochemical defects identified post-mortem. Recent genetic studies have highlighted the mitochondrial and lysosomal areas of cell function as particularly significant in mediating the neurodegeneration of PD. Thus the careful analysis of post-mortem PD brain biochemistry remains a crucial component of research, and one that offers considerable opportunity to pursue etiological factors either by 'reverse biochemistry' i.e. from defective pathway to mutant gene, or by the complex interplay between pathways e.g. mitochondrial turnover by lysosomes. In this review we have documented the spectrum of biochemical defects identified in PD post-mortem brain and explored their relevance to metabolic pathways involved in neurodegeneration. We have highlighted the complex interactions between these pathways and the gene mutations causing or increasing risk for PD. These pathways are becoming a focus for the development of disease modifying therapies for PD. Parkinson's is accompanied by multiple changes in the brain that are responsible for the progression of the disease. We describe here the molecular alterations occurring in postmortem brains and classify them as: Neurotransmitters and neurotrophic factors; Lewy bodies and Parkinson's-linked genes; Transition metals, calcium and calcium-binding proteins; Inflammation; Mitochondrial abnormalities and oxidative stress; Abnormal protein removal and degradation; Apoptosis and transduction pathways. This article is part of a special issue on Parkinson disease.
Recombinant human monoclonal autoantibodies specific for citrulline-containing peptides from phage display libraries derived from patients with rheumatoid arthritis. (2003)

Our report describes the first recombinant human Mab fragments reactive with citrulline-containing peptides. The restricted germline gene usage of these antibodies, and the fact that the VH alleles used are not present in all individuals, may indicate the existence of a genetic predisposition for the development of anticitrulline antibodies in individuals with these germline alleles. The selected antibody clones may facilitate studies on the role of these autoantibodies and their target antigens in the development of RA.
Studies in the pyrolysis of organic bromides. Part III. The pyrolysis of isopropyl bromide (1955)

A. Maccoll and P. J. Thomas, J. Chem. Soc., 1955, 979 DOI: 10.1039/JR9550000979
Artificial Intelligence as a positive and negative factor in global risk (2008)

By far the greatest danger of Artificial Intelligence (AI) is that people conclude too early that they understand it. Of course, this problem is not limited to the field of AI. Jacques Monod wrote: ‘A curious aspect of the theory of evolution is that everybody thinks he understands it’ (Monod, 1974). The problem seems to be unusually acute in Artificial Intelligence. The field of AI has a reputation for making huge promises and then failing to deliver on them. Most observers conclude that AI is hard, as indeed it is. But the embarrassment does not stem from the difficulty. It is difficult to build a star from hydrogen, but the field of stellar astronomy does not have a terrible reputation for promising to build stars and then failing. The critical inference is not that AI is hard, but that, for some reason, it is very easy for people to think they know far more about AI than they actually do. It may be tempting to ignore Artificial Intelligence because, of all the global risks discussed in this book, AI is probably hardest to discuss. We cannot consult actuarial statistics to assign small annual probabilities of catastrophe, as with asteroid strikes. We cannot use calculations from a precise, precisely confirmed model to rule out events or place infinitesimal upper bounds on their probability, as with proposed physics disasters. But this makes AI catastrophes more worrisome, not less. The effect of many cognitive biases has been found to increase with time pressure, cognitive busyness, or sparse information. Which is to say that the more difficult the analytic challenge, the more important it is to avoid or reduce bias. Therefore I strongly recommend reading my other chapter (Chapter 5) in this book before continuing with this chapter. When something is universal enough in our everyday lives, we take it for granted to the point of forgetting it exists. Imagine a complex biological adaptation with ten necessary parts. If each of the ten genes is independently at 50% frequency in the gene pool – each gene possessed by only half the organisms in that species – then, on average, only 1 in 1024 organisms will possess the full, functioning adaptation.
ProbeBuilder: Uncovering Opaque Kernel Data Structures for Automatic Probe Construction (2015)

VM-based inspection tools generally implement probes in the hypervisor to monitor events and the state of kernel of the guest system. The most important function of a probe is to carve information of interest out of the memory of the guest when it is triggered. Implementing probes for a closed-source OS demands manually reverse-engineering the undocumented code/data structures in the kernel binary image. Furthermore, the reverse-engineering result is often non-reusable between OS versions or even kernel updates due to the rapid change of these structures. In this paper, we propose ProbeBuilder, a system automating the process to inference kernel data structures. Based on dynamic execution, ProbeBuilder searches for data structures matching the “pointer-offset-pointer” pattern in guest memory. The sequences of these offsets, which are referred to as dereferences, are then verified by ProbeBuilder with instruction evidence that traverse them. The experiment on Windows kernel shows that ProbeBuilder efficiently narrows thousands of choices for kernel-level probes down to dozens. The finding allows analysts to quickly implement probes, facilitating rapid development/update of inspection tools for different OSes. With these features, ProbeBuilder is the first system capable of automatically generating practical probes that extracts information through dereferences to opaque kernel data structures.
Synthesis and Characterization of Diorganohydrazido(2–) Tungsten Complexes (2007)

Diorganohydrazido(2-) complexes of tungsten (L)Cl4W(NNR2) [R2=Me2, Ph2, -(CH2)5-; L=CH3CN, pyridine] were synthesized by reacting the corresponding 1,1-diorganohydrazine with WCl6, followed by reaction with acetonitrile or pyridine. Crystallographic structure determination of (CH3CN)Cl4W(NNMe2) and (CH3CN)Cl4W(NNPh2) allows a comparison of the structural features of the diorganohydrazido(2-) functionality with varying substituents. Mass spectrometry, thermogravimetric analysis, and preliminary chemical vapor deposition experiments were performed to determine the viability of these complexes as single-source precursors for deposition of WNx and WNxCy films.
Anti-L-NGFR and -CD34 Monoclonal Antibodies Identify Multipotent Mesenchymal Stem Cells in Human Adipose Tissue (2009)

Stem cells hold great promise in tissue engineering for repairing tissues damaged by disease or injury. Mesenchymal stem cells (MSCs) are multipotent cells able to proliferate and differentiate into multiple mesodermal tissues such as bone, cartilage, muscle, tendon, and fat. We have previously reported that the low-affinity nerve growth factor receptor (L-NGFR or CD271) defines a subset of cells with high proliferative, clonogenic, and multipotential differentiation ability in adult bone marrow (BM). It has been recently shown that adipose tissue is an alternative source of adult multipotent stem cells and human adipose-derived stem cells, selected by plastic adherence (PA hASCs), have been extensively characterized for their functional potentials in vitro. In this study, immunoselected L-NGFR(+) and CD34(+) subpopulations have been analyzed and compared with the PA hASCs. Phenotypic profile of freshly purified subpopulations showed an enrichment in the expression of some stem cell markers; indeed, a great percentage of L-NGFR(+) cells co-expressed CD34 and CD117 antigens, whereas the endothelial-committed progenitor markers KDR and P1H12 were mainly expressed on CD34(+) cells. Differently from PA hASCs, the immunoseparated fractions showed high increments in cell proliferation, and the fibroblast colony-forming activity (CFU-F) was maintained throughout the time of culture. Furthermore, the immunoselected populations showed a greater differentiative potential toward adipocytes, osteoblasts, and chondrocyte-like cells, compared to PA hASCs. Our data suggest that both CD34(+) and L-NGFR(+) hASCs can be considered alternative candidates for tissue engineering and regenerative medicine applications.
Primary Reconstruction of Open Depressed Skull Fractures With Titanium Mesh (2008)

Open skull fractures have been traditionally managed in 2 stages: urgent craniotomy and elevation of the fracture with removal of contaminated bone, debridement, and delayed cranioplasty. Primary, single-stage repair of these injures has been said to entail risks such as infections. Recent experience, however, disproved these concerns. We used a primary single-stage reconstruction for patients presenting with open depressed skull fractures. All patients received antibiotic prophylaxis. The patients underwent elevation of the compound fracture and craniotomy if necessary. Debridement was performed, followed by skull reconstruction using a 0.6-mm titanium mesh. We present 5 consecutive male patients (age, 32.2 +/- 15.6 years) who underwent primary reconstruction of open depressed skull fractures. Clinical and radiologic follow-up was performed 2 months after surgery. The duration of the surgery was 2 +/- 1.6 hours. The size of the implanted mesh was 13 +/- 13.1 cm. No infection was detected in our series, with a follow-up period of 22 +/- 6.5 months (range, 16-29 months). The cosmetic result was defined in 4 patients as "excellent" and in 1 patient as "good."Primary reconstruction of open skull fractures with titanium mesh is feasible, safe, and cosmetically preferable than the conventional staged approach. The introduction into clinical practice can be warranted.
Reactions of boron trifluoride with oxides of nitrogen (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of boron trifluoride with oxides of nitrogenAsim B. RayCite this: Inorg. Chem. 1967, 6, 1, 110–113Publication Date (Print):January 1, 1967Publication History Published online1 May 2002Published inissue 1 January 1967https://pubs.acs.org/doi/10.1021/ic50047a025https://doi.org/10.1021/ic50047a025research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Anisotropic prestack depth migration improves the well‐ties at the Ewing Bank Oil Field, Gulf of Mexico (2003)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2003Anisotropic prestack depth migration improves the well‐ties at the Ewing Bank Oil Field, Gulf of MexicoAuthors: Dario CeganiEduardo BerendsonClive HurstHelen DelomeRubén D. MartínezDario CeganiENI E&P, Eduardo BerendsonENI Petroleum, Clive HurstENI Petroleum, Helen DelomePGS Geophysical, and Rubén D. MartínezPGS Geophysicalhttps://doi.org/10.1190/1.1818041 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1818041FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 2003ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2003 Pages: 2452 publication data© 2003 Copyright © 2003 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 03 Jan 2005 CITATION INFORMATION Dario Cegani, Eduardo Berendson, Clive Hurst, Helen Delome, and Rubén D. Martínez, (2003), "Anisotropic prestack depth migration improves the well‐ties at the Ewing Bank Oil Field, Gulf of Mexico," SEG Technical Program Expanded Abstracts : 746-749. https://doi.org/10.1190/1.1818041 Plain-Language Summary PDF DownloadLoading ...
Guidelines for designing BJT amplifiers with low 1/f AM and PM noise (1997)

In this paper we discuss guidelines for designing linear bipolar junction transistor amplifiers with low 1/f amplitude modulation (AM) and phase modulation (PM) noise. These guidelines are derived from a new theory that relates AM and PM noise to transconductance fluctuations, junction capacitance fluctuations, and circuit architecture. We analyze the noise equations of each process for a common emitter (CE) amplifier and use the results to suggest amplifier designs that minimize the 1/f noise while providing other required attributes such as high gain. Although we use a CE amplifier as an example, the procedure applies to other configurations as well. Experimental noise results for several amplifier configurations are presented.