gebhart/patrepeval huggingface dataset:
<title>Advanced systems for automotive applications digital camera systems: the big picture</title> (1997)

The electronic content of the automobile is growing every year. American business analysts estimate that the electrical/electronic content of the average vehicle will be $2000Nehicle by the year 2000. This represents an electrical component industry of $68 Billion/year (using 1995 total world vehicle sales figure). As the demand for increased functionality grows, the complexity of vehicle design increases. At the same time, the need to reduce vehicle costs and the need to maintain high standards ofquality and reliability are forever present. Automobile manufactures have the need to minimise the time taken between the decision to build a particular model and the arrival ofthe first production vehicle (or Job #1). Jaguar's XK8 took 30 months from Project Approval to Job #1. The XK8 included many systems which had been deployed by Jaguar for the first time. Such as the all new V8 powerplant, drive by wire, serial communications and active ride control. Maintaining high levels of quality and reliability within short cycle times requires effective partnerships between Automobile Manufactures and System, or Sub-System, Suppliers. Future vehicle designs will be more dependent on these relationships than ever before with new requirements being generated by pending legislation and by new functionality which will be offered in the next few years.
Formation of Resistant Starch by a Twin‐Screw Extruder (1998)

ABSTRACT The objective of this study was to evaluate the potential to increase the level of resistant starch (RS) in extruded products by optimizing extruder conditions. Three experiments were conducted as randomized complete block designs with two replicates. In the first experiment, corn starch, wheat starch, and potato starch were added at a level of 30% (w/w) to degerminated yellow corn meal to investigate the influence of starch type. In the second experiment, citric acid (CA) monohydrate was added to corn meal at levels of 0, 2.5, 5, and 7.5% (w/w). The third experiment was a full‐factorial arrangement to evaluate the effect of high‐amylose corn starch (HACS) level (0, 15, 30%, w/w) and CA level (0, 5, 7.5%, w/w) at two screw speeds (200 and 300 rpm). In the first experiment, the means for RS plus dietary fiber for the different starch formulations ranged from 1.27 to 2.28%. In experiment 2, adding CA increased RS plus dietary fiber content to a maximum of 5.23% at 7.5% CA. In the third experiment, the means for RS plus dietary fiber ranged from a low of 1.75% for 100% corn meal at 300 rpm to 14.38% for 7.5% CA and 30% HACS at 200 rpm. The results indicated a highly significant positive relationship between CA and RS formation and the same for amylose content. The RS formation had a negative relationship with screw speed, but the influence of screw speed was small when compared with that of CA and HACS.
Ferroelectric Liquid-Crystal Devices (1988)

Current developments in ferroelectric liquid-crystal device physics are reviewed and experimental work in shutter and photoaddressed spatial light modulators is presented.
Genomic Evidence for Island Population Conversion Resolves Conflicting Theories of Polar Bear Evolution (2013)

Despite extensive genetic analysis, the evolutionary relationship between polar bears (Ursus maritimus) and brown bears (U. arctos) remains unclear. The two most recent comprehensive reports indicate a recent divergence with little subsequent admixture or a much more ancient divergence followed by extensive admixture. At the center of this controversy are the Alaskan ABC Islands brown bears that show evidence of shared ancestry with polar bears. We present an analysis of genome-wide sequence data for seven polar bears, one ABC Islands brown bear, one mainland Alaskan brown bear, and a black bear (U. americanus), plus recently published datasets from other bears. Surprisingly, we find clear evidence for gene flow from polar bears into ABC Islands brown bears but no evidence of gene flow from brown bears into polar bears. Importantly, while polar bears contributed <1% of the autosomal genome of the ABC Islands brown bear, they contributed 6.5% of the X chromosome. The magnitude of sex-biased polar bear ancestry and the clear direction of gene flow suggest a model wherein the enigmatic ABC Island brown bears are the descendants of a polar bear population that was gradually converted into brown bears via male-dominated brown bear admixture. We present a model that reconciles heretofore conflicting genetic observations. We posit that the enigmatic ABC Islands brown bears derive from a population of polar bears likely stranded by the receding ice at the end of the last glacial period. Since then, male brown bear migration onto the island has gradually converted these bears into an admixed population whose phenotype and genotype are principally brown bear, except at mtDNA and X-linked loci. This process of genome erosion and conversion may be a common outcome when climate change or other forces cause a population to become isolated and then overrun by species with which it can hybridize.
Natural Regulators of T-Cell Lymphokine Production In Vivo (1992)

The mammalian immune system possesses the intrinsic capacity to evoke a wide variety of functionally distinct effector mechanisms following stimulation by a particular antigenic substance. Such diversity in available responses is absolutely essential to the immunocompetent host, which must continually deal with a diverse set of potential pathogens within its ever-changing environment. The development of appropriate types of immune responses, therefore, represents a highly dynamic process that requires that an equivalent consideration be given to a large array of components, any one of which is capable of modulating the final outcome. While the nature and complexity of the antigen(s), plus the intracellular or extracellular mode of presentation, provide specificity and some selection to the developing process, the route of antigen entry, as well as the physiological status of the host at the time of antigen insult, also contribute significantly to the formation of any immune response. The overall objective of this article is to introduce the concept that platelet-derived growth factor (PDGF) (either preformed or synthesized in response to stimulation), plus a number of steroid hormones (some of which are end-organ metabolized at local tissue sites), can all play significant roles in the genesis of immunologic responses in vivo.
The prothrombin gene variant 20210A in venous and arterial thromboembolism. (1999)

Several hereditary disorders affecting coagulation factors have been identified as prothrombotic risk factors. Recently, the prothrombin 20210 A/G mutation has been identified as a second important polymorphism involved in venous thrombosis. This article reviews all published information about this new procoagulant mutation. Our group has been involved in a number of studies about the role and importance of polymorphisms in thromboembolic disease, including the analysis of the prothrombin 20210 A/G mutation. Moreover, an extensive Medline literature search was made to complete the review using the key words: prothrombin mutation, 20210, venous or arterial thrombosis. The combination of environmental and genetic risk factors determines the relative risk that any individual has of suffering a thrombotic episode. Some genetic mutations affecting coagulation factors have been described. Recently, Poort et al. described a new mutation in the 3'-untranslated region of the prothrombin gene. The prothrombin 20210 G/A mutation, associated with elevated levels of factor II in plasma, significantly increases the risk of developing venous thrombosis. In fact, this polymorphism is the second most important genetic risk factor for venous thrombosis in Caucasian populations. Moreover, and supporting the multifactorial feature of thromboembolic diseases, this mutation greatly increases the possibility of developing a thrombotic episode when combined with other environmental or genetic risk factors. The role of this procoagulant mutation in arterial vascular disease is, however, unclear.
Lifetime extension of XeCl and KrCl lasers with additives (1980)

The stabilization and extension of operation of XeCl (308 nm) and KrCl (222 nm) excimer lasers by the addition of very low concentrations of hydrogen gas is described. Lifetime extension of a sealed-off XeCl laser operating at 8 W and 150 Hz is reported, with more than three million shots to half power. Spectroscopic analysis of the laser gas indicates a large reduction in a discharge-induced absorption feature below 230 nm; no absorption is observed at 308 nm.
Ureterocele (1926)

No AccessJournal of Urology1 Nov 1926Ureterocele Damon A. Brown Damon A. BrownDamon A. Brown More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)73417-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1926 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByLazarus J (2018) Cystic Dilatation of the Lower end of the Ureter: Special Reference to the Transurethral Treatment with the High Frequency Cutting CurrentJournal of Urology, VOL. 36, NO. 2, (139-149), Online publication date: 1-Aug-1936. Volume 16Issue 5November 1926Page: 363-368 Advertisement Copyright & Permissions© 1926 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Damon A. Brown More articles by this author Expand All Advertisement Loading ...
A Survey of Recent Developments in the Law: Insurance Law (2000)

the Minnesota Court of Appeals defined the term "resident of a residence premises" as used in a renter's insurance policy's bodily injury exclusion.'In Illinois Farmers Insurance Co. v. Neumann, the Minnesota Court of Appeals concluded that a "resident of a residence" is a broader term than "resident of a household., 2 Specifically, the court held that the term "resident of a residence" recognizes the fact that it is common 3 for unrelated people to live together in a rental unit.Furthermore, the court found that a person who does not fit the definition of a "resident of a household" might fit the broader definition of a "resident of a residence., 4 In Illinois Farmers, Katina Neumann rented one-half of a duplex in St. Paul, Minnesota. 5Neumann sublet one of her rooms to Barbara Brenny, and Neumann and Brenny shared the expenses of rent and utilities equally. 6In September 1995, Neumann's dog bit Brenny causing injures to Brenny that required medical attention Brenny also lost wages."Brenny then sued Neumann for compensatory damages, and Neumann submitted a claim for coverage under her renter's insurance policy. 9Illinois Farmers Insurance Co., the insurance company that wrote Neumann's policy, sought a declaratory judgment determining that Neumann's policy did not provide coverage for the September 1995, dog-bite
Rapid development of an inactivated vaccine for SARS-CoV-2 (2020)

Abstract The COVID-19 pandemic caused by SARS-CoV-2 has brought about an unprecedented crisis, taking a heavy toll on human health, lives as well as the global economy. There are no SARS-CoV-2-specific treatments or vaccines available due to the novelty of this virus. Hence, rapid development of effective vaccines against SARS-CoV-2 is urgently needed. Here we developed a pilot-scale production of a purified inactivated SARS-CoV-2 virus vaccine candidate (PiCoVacc), which induced SARS-CoV-2-specific neutralizing antibodies in mice, rats and non-human primates. These antibodies potently neutralized 10 representative SARS-CoV-2 strains, indicative of a possible broader neutralizing ability against SARS-CoV-2 strains circulating worldwide. Immunization with two different doses (3μg or 6 μg per dose) provided partial or complete protection in macaques against SARS-CoV-2 challenge, respectively, without any antibody-dependent enhancement of infection. Systematic evaluation of PiCoVacc via monitoring clinical signs, hematological and biochemical index, and histophathological analysis in macaques suggests that it is safe. These data support the rapid clinical development of SARS-CoV-2 vaccines for humans. One Sentence Summary A purified inactivated SARS-CoV-2 virus vaccine candidate (PiCoVacc) confers complete protection in non-human primates against SARS-CoV-2 strains circulating worldwide by eliciting potent humoral responses devoid of immunopathology
Sequence and gene expression evolution of paralogous genes in willows (2015)

Whole genome duplications (WGD) have had strong impacts on species diversification by triggering evolutionary novelties, however, relatively little is known about the balance between gene loss and forces involved in the retention of duplicated genes originating from a WGD. We analyzed putative Salicoid duplicates in willows, originating from the Salicoid WGD, which took place more than 45 Mya. Contigs were constructed by de novo assembly of RNA-seq data derived from leaves and roots from two genotypes. Among the 48,508 contigs, 3,778 pairs were, based on fourfold synonymous third-codon transversion rates and syntenic positions, predicted to be Salicoid duplicates. Both copies were in most cases expressed in both tissues and 74% were significantly differentially expressed. Mean Ka/Ks was 0.23, suggesting that the Salicoid duplicates are evolving by purifying selection. Gene Ontology enrichment analyses showed that functions related to DNA- and nucleic acid binding were over-represented among the non-differentially expressed Salicoid duplicates, while functions related to biosynthesis and metabolism were over-represented among the differentially expressed Salicoid duplicates. We propose that the differentially expressed Salicoid duplicates are regulatory neo- and/or subfunctionalized, while the non-differentially expressed are dose sensitive, hence, functionally conserved. Multiple evolutionary processes, thus drive the retention of Salicoid duplicates in willows.
Ultra Performance Liquid Chromatography Isotope Dilution Tandem Mass Spectrometry for the Absolute Quantification of Proteins and Peptides (2008)

A selective, rapid, and sensitive 12.7-min ultra performance liquid chromatography-isotope dilution tandem mass spectrometry (UPLC-ID/MS/MS) method was developed and compared to conventional high-performance liquid chromatography-isotope dilution tandem mass spectrometry (HPLC-ID/MS/MS) for the absolute quantitative determination of multiple proteins from complex matrixes. The UPLC analysis was carried out on an Acquity UPLC ethylene-bridged hybrid (BEH) C18 reversed-phase column (50 x 2.1 mm i.d., 1.7-microm particle size) with gradient elution at a flow rate of 300 microL/min. For the HPLC separation, a similar gradient profile on a reversed-phase C18 column with dimensions of 150 x 1.0 mm at a flow rate of 30 microL/min was utilized. The aqueous and organic mobile phases were 0.1% formic acid in water and acetonitrile, respectively. Detection was performed on a triple-quadrupole mass spectrometer operated in the multiple reaction monitoring mode. Linear calibration curves were obtained in the concentration range of 10-90 fmol/microL. Relative standard deviation values equal to or less than 6.5% were obtained by the UPLC-ID/MS/MS method, thus demonstrating performance equivalent to conventional HPLC-ID/MS/MS for isotope dilution quantification of peptides and proteins. UPLC provides additional dimensions of rapid analysis time and high-sample throughput, which expands laboratory emergency response capabilities over conventional HPLC.
Injurious Mechanical Ventilation and End-Organ Epithelial Cell Apoptosis and Organ Dysfunction in an Experimental Model of Acute Respiratory Distress Syndrome (2003)

Mechanical ventilation can lead to epithelial cell apoptosis in the kidney and small intestine, accompanied by biochemical evidence of organ dysfunction. This may partially explain the high rate of MODS observed in patients with ARDS and the decrease in morbidity and mortality in patients treated with a lung protective strategy.
Dynamic Sensor Collaboration Via Sequential Monte Carlo (2004)

We consider the application of sequential Monte Carlo (SMC) methods for Bayesian inference to the problem of information-driven dynamic sensor collaboration in clutter environments for sensor networks. The dynamics of the system under consideration are described by nonlinear sensing models within randomly deployed sensor nodes. The exact solution to this problem is prohibitively complex due to the nonlinear nature of the system. The SMC methods are, therefore, employed to track the probabilistic dynamics of the system and to make the corresponding Bayesian estimates and predictions. To meet the specific requirements inherent in sensor network, such as low-power consumption and collaborative information processing, we propose a novel SMC solution that makes use of the auxiliary particle filter technique for data fusion at densely deployed sensor nodes, and the collapsed kernel representation of the a posteriori distribution for information exchange between sensor nodes. Furthermore, an efficient numerical method is proposed for approximating the entropy-based information utility in sensor selection. It is seen that under the SMC framework, the optimal sensor selection and collaboration can be implemented naturally, and significant improvement is achieved over existing methods in terms of localizing and tracking accuracies.
The Decline of Androgen Levels in Elderly Men and Its Clinical and Therapeutic Implications (2005)

Aging in men is accompanied by a progressive, but individually variable decline of serum testosterone production, more than 20% of healthy men over 60 yr of age presenting with serum levels below the range for young men. Albeit the clinical picture of aging in men is reminiscent of that of hypogonadism in young men and decreased testosterone production appears to play a role in part of these clinical changes in at least some elderly men, the clinical relevancy of the age-related decline in sex steroid levels in men has not been unequivocally established. In fact, minimal androgen requirements for elderly men remain poorly defined and are likely to vary between individuals. Consequently, borderline androgen deficiency cannot be reliably diagnosed in the elderly, and strict differentiation between "substitutive" and "pharmacological" androgen administration is not possible. To date, only a few hundred elderly men have received androgen therapy in the setting of a randomized, controlled study, and many of these men were not androgen deficient. Most consistent effects of treatment have been on body composition, but to date there is no evidence-based documentation of clinical benefits of androgen administration to elderly men with normal or moderately low serum testosterone in terms of diminished morbidity or of improved survival or quality of life. Until the long-term risk-benefit ratio for androgen administration to elderly is established in adequately powered trials of longer duration, androgen administration to elderly men should be reserved for the minority of elderly men who have both clear clinical symptoms of hypogonadism and frankly low serum testosterone levels.
Human c- <i>myc</i> Transcription Factor PuF Identified as nm23-H2 Nucleoside Diphosphate Kinase, a Candidate Suppressor of Tumor Metastasis (1993)

A human gene encoding the c-myc purine-binding transcription factor PuF was identified by screening of a cervical carcinoma cell complementary DNA library with a DNA fragment containing PuF binding sites. The 17-kilodalton bacterially produced PuF was shown to have biological activity and properties similar to that of human PuF. DNA sequence analysis of recombinant PuF revealed perfect identity with the human nm23-H2 nucleoside diphosphate kinase gene, a potential negative regulator of cancer metastasis. These results provide a link between nm23 and the c-myc oncogene and suggest that the nm23 protein can function in vitro in the transcriptional regulation of c-myc expression.
Automatic Identification of Conceptual Metaphors With Limited Knowledge (2013)

Full natural language understanding requires identifying and analyzing the meanings of metaphors, which are ubiquitous in both text and speech. Over the last thirty years, linguistic metaphors have been shown to be based on more general conceptual metaphors, partial semantic mappings between disparate conceptual domains. Though some achievements have been made in identifying linguistic metaphors over the last decade or so, little work has been done to date on automatically identifying conceptual metaphors. This paper describes research on identifying conceptual metaphors based on corpus data. Our method uses as little background knowledge as possible, to ease transfer to new languages and to mini- mize any bias introduced by the knowledge base construction process. The method relies on general heuristics for identifying linguistic metaphors and statistical clustering (guided by Wordnet) to form conceptual metaphor candidates. Human experiments show the system effectively finds meaningful conceptual metaphors.
ROOOH: a missing piece of the puzzle for OH measurements in low-NO environments? (2019)

Abstract. Field campaigns have been carried out with the FAGE (fluorescence assay by gas expansion) technique in remote biogenic environments in the last decade to quantify the in situ concentrations of OH, the main oxidant in the atmosphere. These data have revealed concentrations of OH radicals up to a factor of 10 higher than predicted by models, whereby the disagreement increases with decreasing NO concentration. This was interpreted as a major lack in our understanding of the chemistry of biogenic VOCs (volatile organic compounds), particularly isoprene, which are dominant in remote pristine conditions. But interferences in these measurements of unknown origin have also been discovered for some FAGE instruments: using a pre-injector, all ambient OH is removed by fast reaction before entering the FAGE cell, and any remaining OH signal can be attributed to an interference. This technique is now systematically used for FAGE measurements, allowing the reliable quantification of ambient OH concentrations along with the signal due to interference OH. However, the disagreement between modelled and measured high OH concentrations of earlier field campaigns as well as the origin of the now-quantifiable background OH is still not understood. We present in this paper the compelling idea that this interference, and thus the disagreement between model and measurement in earlier field campaigns, might be at least partially due to the unexpected decomposition of a new class of molecule, ROOOH, within the FAGE instruments. This idea is based on experiments, obtained with the FAGE set-up of the University of Lille, and supported by a modelling study. Even though the occurrence of this interference will be highly dependent on the design and measurement conditions of different FAGE instruments, including ROOOH in atmospheric chemistry models might reflect a missing piece of the puzzle in our understanding of OH in clean atmospheres.