gebhart/patrepeval huggingface dataset:
2500V, 600A gate turn-off thyristor (GTO) (1979)

The vital point for 2500V, 600A GTO design is to establish a principle for increasing maximum gate turn-off current (I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ATO</inf> ), while keeping overall thyristor characteristics in reasonable balance. High I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ATO</inf> was attained by decreasing p-base surface resistance to below a certain limit, as well as decreasing n-emitter finger width. Excellent thyristor characteristics were obtained by adopting thick p-base layer with as low as possible acceptor concentration. From a device process point of view, introducing a new annealing process of phosphorus redeposition increased carrier lifetime in the p-base to a sufficiently high level. This process contributed most strikingly to improving the off-state voltage.
Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule (2017)

Indirubins have been identified as potent ATP-competitive protein kinase inhibitors. Structural modifications in the 5- and 3'-position have been extensively investigated, but the impact of substituents in 5'-position is not equally well-studied. Here, we report the synthesis of new indirubin 3'- and 5'-derivatives in the search of water-soluble indirubins by introducing basic centers. Antiproliferative activity of all compounds in tumor cells was evaluated along with kinase inhibition of selected compounds. The results show the 3'-position to tolerate large substituents without compromising activity, whereas bulk and rigid substituents in 5'-position appear unfavorable. Screening molecular targets of water-soluble 3'-oxime ethers revealed 6ha as preferential inhibitor of insulin-like growth factor 1 receptor (IGF-1R) in a panel of 22 protein kinases and in cells. Consistently, 6ha inhibited tumor cell growth in the NCI 60 cell line panel and induced apoptosis. The results indicate that the 5'-position provides limited space for chemical modifications and identify 6ha as a potent water-soluble indirubin-based IGF-1R inhibitor.
Chip-level MMSE equalization at the edge of the cell (2002)

We examine the performance of two linear equalizers for a CDMA downlink over a frequency-selective multipath channel: the traditional RAKE receiver, and a chip-level MMSE (minimum mean square error) equalizer. The mobile-station assumed to be midway between two base-stations. We examine the system performance for one versus two receive antennas, and normal operation versus soft-hand-off mode. MMSE is confirmed to outperform RAKE. Also, having two receive antennas is superior to having a single antenna. Simulation results are presented for uncoded BPSK and 16-QAM, and BPSK with convolutional coding.
Design and use of an inhalation chamber for air pollution studies in small animals. (1978)

Environmental chambers provide a convenient means of studying the toxicology of gases in experimental animals. The specialised equipment needed for these studies is not commercially available. This paper reports on the design, construction and performance of a simple, and inexpensive, inhalation chamber and gas mixing unit for air pollution studies in small laboratory animals. Provision has been made for controlling the mixing of gases, the ventilation rate, the even distribution of gases in the chamber and for the removal of vented gases to prevent the hazard of air pollution in the laboratory animal facility. No significant differences were found between the food and water consumption and body mass gain of a group of rats housed in the chamber for 5 days and a control group housed im similar cages located in a rodent room and managed under conventional laboratory conditions. The chamber fulfills all the requirements for an animal inhalation system.
Configurable timing controller design for active matrix electrophoretic display with 16 gray levels (2009)

To design various electronic papers, the panel designers may adopt different types of electrophoretic materials and active matrix backplanes for resolution, speed, and contrast ratio considerations. The electrical and optical characteristics are different for various application conditions so that a good timing controller should provide an easy way to modify waveforms accordingly. In this paper, we present a configurable timing controller for active matrix electrophoretic displays. It can support all variations of driving waveforms that are based on pulse width modification. The performance of the controller has been applied on several practical EPD systems whose resolutions are not identical.
Coherency enhancement on 3D seismic data by dip detection and dip selection (2007)

Historically, 3D land data has been noisy when compared to 3D marine data. Recently we have witnessed the advent of high density recordings with folds in excess of 300 that help to reduce noise on the final images. However, low fold land 3D, mostly old vintage, is still commonly seen in processing shops and on interpreter's workstations. To pull signal from such post‐stack data and, more challengingly, from even noisier pre‐stack offset class data, is a challenge that this paper aims to address.
A trilogy of glucocorticoid receptor actions (2016)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Shadow maps and projective texturing in X3D (2010)

We propose a number of X3D extensions to enable shadows in the virtual worlds. Our higher-level extensions are an easy way to request shadows independently of their implementation. Lower-level extensions allow to control the details of shadow maps generation and projective texture mapping. Together, they allow the authors to activate real-time dynamic shadows on 3D scenes. The extensions expose also projective texture mapping for purposes other than shadows, for example we can cast a color texture from a light source. Introduced concepts map naturally to any basic shadow maps implementation, and integrate nicely with existing X3D components like textures and shaders.
Radioimmunoassay studies of human apolipoprotein E. (1980)

A C T This report describes the development and first applications of a sensitive and specific double antibody radioimmunoassay for human apolipoprotein E (apoE). ApoE was purified from the very low density lipoproteins of hypertriglyceridemic patients by heparin-agarose affinity chromatography, DEAE-cellulose chromatography, and preparative polyacrylamide gel electrophoresis. The purified apoprotein had an amino acid composition characteristic of apoE and resulted in the production of monospecific antisera when in- jected into rabbits. The radioimmunoassay, which was carried out in the presence of 5 mM sodium decyl sulfate, had a working range of 0.8-12 ng. The within- assay coefficient ofvariation was 9% and the coefficient of variation for systematic between-assay variability was 3%. Prior delipidation of samples with organic solvents did not alter their immunoreactivity.
ChemInform Abstract: PREPARATION AND PROPERTIES OF HYDRIDE TRIPHENYLPHOSPHINE RUTHENIUM COMPLEXES WITH 3‐FORMYL (OR ACYL) PROPIONATE (RUH(OCOCHRCHRCOR′)(PPH3)3) (R = H, CH3, C2H5; R′ = H, CH3, C6H5) AND WITH 2‐FORMYL (OR ACYL) BENZOATE (RUH(O‐OCOC6H4COR′)(PPH3)3) (R′ = H, CH3) (1982)

Abstract Die cyclischen Carbonsäureanhydride (I) reagieren mit dem Rutheniumkomplex (II) zu den Aldehyden (III), die mit Chlorwasserstoff in die Lactone (IV) übergehen.
Novel Organometallic Building Blocks for Molecular Crystal Engineering. 2. Synthesis and Characterization of Pyridyl and Pyrimidyl Derivatives of Diboronic Acid, [Fe(η<sup>5</sup>-C<sub>5</sub>H<sub>4</sub>-B(OH)<sub>2</sub>)<sub>2</sub>], and of Pyridyl Boronic Acid, [Fe(η<sup>5</sup>-C<sub>5</sub>H<sub>4</sub>-4-C<sub>5</sub>H<sub>4</sub>N)(η<sup>5</sup>-C<sub>5</sub>H<sub>4</sub>-B(OH)<sub>2</sub>)] (2003)

The synthesis and structural characterization of the ferrocenyl diboronic acid complex [Fe(η5-C5H4-B(OH)2)2] (1) and of its products of monosubstitution, [Fe(η5-C5H4-4-C5H4N)(η5-C5H4-B(OH)2)] (2 in three polymorphic modifications, 2a−c), and of disubstitution, [Fe(η5-C5H4-4-C5H4N)2] (4), [Fe(η5-C5H4-C6H4-4-C5H4N)2] (6), and [Fe(η5-C5H4-5-C4H3N2)2] (7), are reported together with an investigation of the mode of supramolecular bonding in the solid state. The competition between the hydrogen-bonding interactions of the (B)O−H···O(B) and (B)O−H···N types in the cases of crystalline 1 and 2 has been investigated. The B(OH)2 group provides two hydrogen bonding donor groups and two acceptors, forming mainly cyclic hydrogen-bonded systems in topological analogy with a primary amido group. Compounds 4, 6, and 7 are examples of neutral disubstituted pyridyl and pyrimidyl ferrocenyl complexes with potentials as supramolecular ligands. The compounds [Fe(η5-C5H4-4-C5H4NH)(η5-C5H4-B(OH)2)][NO3] (3a), [Fe(η5-C5H4-4-C5H4NH)(η5-C5H4-B(OH)2)][SO4]·3H2O (3b), and [Fe(η5-C5H4-4-C5H4NH)2][Cl]2·4H2O (5) have been obtained by treatment with acids of compounds 2 and 4, respectively. The interionic hydrogen bonds have also been investigated.
Cached sufficient statistics for efficient machine learning with large datasets (1998)

This paper introduces new algorithms and data structures for quick counting for machine learning datasets. We focus on the counting task of constructing contingency tables, but our approach is also...
Liposome-mediated Transfection of<i>Lactobacillus casei</i>Spheroplasts (1984)

Journal Article Liposome-mediated Transfection of Lactobacillus casei Spheroplasts Get access Mariko Shimizu-Kadota, Mariko Shimizu-Kadota Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo 186, Japan Search for other works by this author on: Oxford Academic Google Scholar Satoshi Kudo Satoshi Kudo Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo 186, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 48, Issue 4, 1 April 1984, Pages 1105–1107, https://doi.org/10.1080/00021369.1984.10866279 Published: 01 April 1984 Article history Received: 15 December 1983 Published: 01 April 1984
Integrated-optic acoustically tunable reflection filter (1989)

We demonstrate a two-stage, integrated-optic, acoustically tunable filter formed by reflecting the output of a single stage acousto-optic filter back through the filter by means of an integral mirror. Relative to a single-stage device, this double-pass configuration provides greatly improved sidelobe suppression (to approximately -20 dB) and a 72% reduction in filter bandwidth (to less than 0.9 nm at a wavelength of 1.52 microm). The performance of this device is shown to be equal to the far more difficult to fabricate cascaded pair of strictly matched acousto-optic filters.
Strong association of fascin expression with triple negative breast cancer and basal-like phenotype in African-American women (2013)

These results suggest that fascin is a marker for TN subtype having a basal-like phenotype and decreased overall survival. Fascin may represent a target for therapy in TNBC in AA women.
A multiangle imaging spectroradiometer for terrestrial remote sensing from the earth observing system (1991)

Abstract The Multiangle Imaging SpectroRadiometer (MISR) instrument for the Earth Observing System (EOS) will provide a unique opportunity for studying the ecology and climate of the Earth through the acquisition of systematic, global multiangle imagery in reflected sunlight. MISR employs nine discrete cameras pointed at fixed angles, viewing the nadir direction and forward and aftward along the spacecraft ground track. Each camera is a charge‐coupled‐device –based pushbroom imager. Within a 7‐minute period, every point in a 204‐km‐wide swath is imaged at the nine viewing angles, ensuring observations acquired under virtually identical illumination and atmospheric conditions. The cameras will image the Earth in the nadir direction and at 30.7°, 45.6°, 60.0°, and 72.5° forward and aftward of the local vertical at the Earth's surface. Images at each angle will be obtained in four spectral bands centered at 440, 550, 670, and 860 nm. MISR is capable of taking image data in two different spatial resolution modes: Local Mode, in which selected targets are observed with 240‐m spatial sampling, and Global Mode, where the entire sunlit Earth is observed continuously with 1.92‐km sampling. Absolute radiometric calibration of the MISR instrument will be performed in‐flight using special on‐board hardware. The data produced by MISR will be valuable in a number of scientific discipline areas, and MISR images and geophysical products will be archived at the EOS Data and Information System to make them available to the broad scientific community.
DYNAMIC COMPRESSION OF SOFT POROUS MEDIA: FROM FINITE TO INFINITE DOMAIN (2011)

In recent studies about lift generation in porous media, dynamic compression experiments have been performed using a porous-walled cylinder-piston apparatus, where the air trapped inside a porous layer underneath the loaded piston was forced out through the porous wall to the ambient, namely, "finite domain," oversimplifying real applications where transiently trapped fluid is squeezed out to the surrounding porous structures, that is, "infinite domain." In the current paper we treat this shortcoming experimentally. A soft, polyester, fibrous, porous material was chosen for the study. Its microstructure was characterized using a scanning electronic microscope. Its porosity was measured using a water-displacement method, and its permeability was determined using a permeameter. The cylinder-piston apparatus was first used in a quasi-static experiment to examine the material’s stiffness and was then used in the dynamic compaction experiments in the infinite domain. Detailed pressure distribution was examined. The results indicate that the air lifting force is enhanced by 25 to 30% for the infinite domain over the finite domain due to the existence of the surrounding porous material. The pore pressure, however, relaxes rapidly in the undeformed surroundings. These observations improve our understanding of the dynamic response of soft porous media under rapid compression.
A Light-Weight Permutation Based Method for Data Privacy in Mobile Cloud Computing (2015)

Cloud computing paradigm provides virtual IT infrastructures with a set of resources that are shared with multi-tenant users. Data Privacy is one of the major challenges when users outsource their data to a cloud computing system. Privacy can be violated by the cloud vendor, vendor's authorized users, other cloud users, unauthorized users, or external malicious entities. Encryption is one of the solutions to protect and maintain privacy of cloud-stored data. However, encryption methods are complex and expensive for mobile devices. In this paper, we propose a new light-weight method for mobile clients to store data on one or multiple clouds by using pseudo-random permutation based on chaos systems. The proposed method can be used in the client mobile devices to store data in the cloud(s) without using cloud computing resources for encryption to maintain user's privacy. We consider JPEG image format as a case study to present and evaluate the proposed method. Our experimental results show that the proposed method achieve superior performance compared to over encryption methods, such as AES and encryption on JPEG encoders while protecting the mobile user data privacy. We review major security attack scenarios against the proposed method that shows the level of security.
Metalations by organolithium compounds (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleMetalations by organolithium compoundsJ. M. Mallan and R. L. BebbCite this: Chem. Rev. 1969, 69, 5, 693–755Publication Date (Print):October 1, 1969Publication History Published online1 May 2002Published inissue 1 October 1969https://pubs.acs.org/doi/10.1021/cr60261a006https://doi.org/10.1021/cr60261a006research-articleACS PublicationsRequest reuse permissionsArticle Views2650Altmetric-Citations122LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Shear Strength Parameters Obtained from Static Cone Penetration Tests (1985)

Effective shear strength parameters may be obtained from cone penetration tests with pore-pressure measurements. The theoretical solutions presented below cover the interpretation of measurements in (1) sandy soils with drained conditions around the penetrating tip and (2) clayey soils with excess pore-pressure around the tip. A chart for approximate classification through point resistance and pore-pressure ratio is included. The method of interpretation is cone penetration tests in marine sediments and the results obtained are compared to laboratory test results on soil specimens from neighboring borings.
Orientation dependence of ballistic electron transport and impact ionisation (1980)

The orientation dependence of ballistic electron transport in GaAs is investigated using the pseudopotential band structure. It is shown that a single scattering event can permit electron impact-ionisation threshold energies to be reached in the 〈111〉 and 〈100〉 directions. This is in contrast to ballistic calculations, where simple thresholds do not exist in these directions.
Integrating information retrieval and domain specific approaches for browsing and retrieval in object-oriented class libraries (1991)

article Free Access Share on Integrating information retrieval and domain specific approaches for browsing and retrieval in object-oriented class libraries Authors: Richard Helm I.B.M. Thomas J. Watson Research Center, P.O. Box 704, Yorktown Heights, NY I.B.M. Thomas J. Watson Research Center, P.O. Box 704, Yorktown Heights, NYView Profile , Yoëlle S. Maarek I.B.M. Thomas J. Watson Research Center, P.O. Box 704, Yorktown Heights, NY I.B.M. Thomas J. Watson Research Center, P.O. Box 704, Yorktown Heights, NYView Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 26Issue 11Nov. 1991 pp 47–61https://doi.org/10.1145/118014.117958Online:01 November 1991Publication History 40citation536DownloadsMetricsTotal Citations40Total Downloads536Last 12 Months15Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Case 6-2004: Severe Burns from a Nightclub Fire (2004)

International audience
Identification of an <scp>ABCB1</scp> (P‐glycoprotein)‐positive carfilzomib‐resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye <scp>CDy1</scp> (2013)

Multiple myeloma (MM) is characterized by the malignant expansion of differentiated plasma cells. Although many chemotherapeutic agents display cytotoxic activity toward MM cells, patients inevitably succumb to their disease because the tumor cells become resistant to the anticancer drugs. The cancer stem cell hypothesis postulates that a small subpopulation of chemotherapy-resistant cancer cells is responsible for propagation of the tumor. Herein we report that efflux of the pluripotent stem cell dye CDy1 identifies a subpopulation in MM cell lines characterized by increased expression of P-glycoprotein, a member of the ABC (ATP-binding cassette) superfamily of transporters encoded by ABCB1. We also demonstrate that ABCB1-overexpressing MM cells are resistant to the second-generation proteasome inhibitor carfilzomib that recently received accelerated approval for the treatment of therapy-refractive MM by the U.S. Food and Drug Administration. Moreover, increased resistance to carfilzomib in sensitive MM cells following drug selection was associated with upregulation of ABCB1 cell-surface expression which correlated with increased transporter activity as measured by CDy1 efflux. We further show that chemosensitization of MM cells to carfilzomib could be achieved in vitro by cotreatment with vismodegib, a hedgehog pathway antagonist which is currently in MM clinical trials. CDy1 efflux may therefore be a useful assay to determine whether high expression of ABCB1 is predictive of poor clinical responses in MM patients treated with carfilzomib. Our data also suggest that inclusion of vismodegib might be a potential strategy to reverse ABCB1-mediated drug resistance should it occur.
Image Saliency Mapping and Ranking Using an Extensible Visual Attention Model Based on MPEG-7 Feature Descriptors (2005)

In visual perception, finding regions of interest in a scene is very important in the carrying out visual tasks. Recently there have been a number of works proposing saliency detectors and visual attention models. In this paper, we propose an extensible visual attention framework based on MPEG-7 descriptors. Hotspots in an image are detected from the combined saliency map obtained from multiple feature maps of multi-scales. The saliency concept is then further extended and we propose a saliency index for the ranking of images on their interestingness. Simulations on hotspots detection and automatic image ranking are conducted and statistically tested with a user test. Results show that our method captures more important regions of interest and the automatic ranking positively agrees to user rankings.
Increased signal-to-noise ratio of sensorless control using current oversampling (2015)

This paper presents a novel approach based on current oversampling with low computational effort that significantly increases the signal-to-noise ratio with regard to sensorless control of permanent magnet synchronous machines at low and zero speed. The novel method is based on calculating arithmetic averages of all current samples taken during a period of pulse width modulation (PWM). This algorithm is implemented in a field programmable gate array (FPGA). Compared to a conventional current measurement with single sampling, the arithmetic average of the current samples has a much higher signal-to-noise ratio than the current samples themselves. The current derivative, which is used for sensorless control, is then calculated from the difference between two consecutive current averages. Experimental results validate the functionality of the novel approach.
Assay for type C virus in mouse sera based on particulate reverse transcriptase activity (1976)

Assay of particulate reverse transcriptase activity in the sera from feral mice naturally infected with type C virus provides a sensitive and rapid procedure for the determination of in vivo virus infection. The results compare well with assays for infectious virus and with complement fixation or competitive radio-immunoassays for the p30 internal antigen of the virus.