gebhart/patrepeval huggingface dataset:
King Lear's Revenges (1960)

Research Article| September 01 1960 King Lear's Revenges Robert P. Adams Robert P. Adams Search for other works by this author on: This Site Google Modern Language Quarterly (1960) 21 (3): 223–227. https://doi.org/10.1215/00267929-21-3-223 Cite Icon Cite Share Icon Share Twitter Permissions Search Site Citation Robert P. Adams; King Lear's Revenges. Modern Language Quarterly 1 September 1960; 21 (3): 223–227. doi: https://doi.org/10.1215/00267929-21-3-223 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsModern Language Quarterly Search Advanced Search The text of this article is only available as a PDF. Copyright © 1960 by Duke University Press1960 Article PDF first page preview Close Modal Issue Section: Articles You do not currently have access to this content.
Photoinduced crosslinking of polyolefine blends. I. Crosslinking of LDPE, PP, and LDPE/PP blends (1995)

Abstract Photocrosslinking of low‐density polyethylene, (LDPE), polypropylene (PP) and their blends was investigated using xanthone and triallyl cyanurate as a photoinitiator and a coagent, respectively. The influence of the change of UV‐irradiation conditions on the yield of photoinitiated processes was found to be very similar at any composition, while the crosslinking efficiency decreases with increase of PP content in the blend. The mechanism of the TAC action in photocrosslinking process was proposed and the effect of TAC reactions is discussed with regards to the effectivity of crosslinking of LDPE, PP, or the blends. © 1995 John Wiley & Sons, Inc.
A Kinetic-Based Model of Radiation-Induced Intercellular Signalling (2013)

It is now widely accepted that intercellular communication can cause significant variations in cellular responses to genotoxic stress. The radiation-induced bystander effect is a prime example of this effect, where cells shielded from radiation exposure see a significant reduction in survival when cultured with irradiated cells. However, there is a lack of robust, quantitative models of this effect which are widely applicable. In this work, we present a novel mathematical model of radiation-induced intercellular signalling which incorporates signal production and response kinetics together with the effects of direct irradiation, and test it against published data sets, including modulated field exposures. This model suggests that these so-called "bystander" effects play a significant role in determining cellular survival, even in directly irradiated populations, meaning that the inclusion of intercellular communication may be essential to produce robust models of radio-biological outcomes in clinically relevant in vivo situations.
Directly patterned low voltage planar tungsten lateral field emission structures (1993)

Using high resolution electron beam lithography it has been possible to directly pattern planar structures which exhibit lateral conduction characteristics that are consistent with field emission. Two terminal and three terminal structures have been fabricated in a tungsten layer on an insulating substrate using a combination of an aluminum lift-off and dry etching. By careful control of the electrode spacings it has been possible to ensure that the emission occurs for voltages less than 100 V. In the three terminal structures fabricated a high proportion of the emitted current reaches the collector.
Mild and Reversible Dehydration of Primary Amides with PdCl<sub>2</sub>in Aqueous Acetonitrile (2005)

[reaction: see text] A new, mild, and reversible method to convert primary amides to nitriles in good yields using PdCl2 in aqueous acetonitrile is described.
Strongly Lewis Acidic Metal–Organic Frameworks for Continuous Flow Catalysis (2019)

The synthesis of highly acidic metal-organic frameworks (MOFs) has attracted significant research interest in recent years. We report here the design of a strongly Lewis acidic MOF, ZrOTf-BTC, through two-step transformation of MOF-808 (Zr-BTC) secondary building units (SBUs). Zr-BTC was first treated with 1 M hydrochloric acid solution to afford ZrOH-BTC by replacing each bridging formate group with a pair of hydroxide and water groups. The resultant ZrOH-BTC was further treated with trimethylsilyl triflate (Me<sub>3</sub>SiOTf) to afford ZrOTf-BTC by taking advantage of the oxophilicity of the Me<sub>3</sub>Si group. Electron paramagnetic resonance spectra of Zr-bound superoxide and fluorescence spectra of Zr-bound <i>N</i>-methylacridone provided a quantitative measurement of Lewis acidity of ZrOTf-BTC with an energy splitting (Δ<i>E</i>) of 0.99 eV between the π<sub><i>x</i></sub>* and π<sub><i>y</i></sub>* orbitals, which is competitive to the homogeneous benchmark Sc(OTf)<sub>3</sub>. ZrOTf-BTC was shown to be a highly active solid Lewis acid catalyst for a broad range of important organic transformations under mild conditions, including Diels-Alder reaction, epoxide ring-opening reaction, Friedel-Crafts acylation, and alkene hydroalkoxylation reaction. The MOF catalyst outperformed Sc(OTf)<sub>3</sub> in terms of both catalytic activity and catalyst lifetime. Moreover, we developed a ZrOTf-BTC@SiO<sub>2</sub> composite as an efficient solid Lewis acid catalyst for continuous flow catalysis. The Zr centers in ZrOTf-BTC@SiO<sub>2</sub> feature identical coordination environment to ZrOTf-BTC based on spectroscopic evidence. ZrOTf-BTC@SiO<sub>2</sub> displayed exceptionally high turnover numbers (TONs) of 1700 for Diels-Alder reaction, 2700 for epoxide ring-opening reaction, and 326 for Friedel-Crafts acylation under flow conditions. We have thus created strongly Lewis acidic sites in MOFs via triflation and constructed the MOF@SiO<sub>2</sub> composite for continuous flow catalysis of important organic transformations.
Linear block codes for frequency selective PLC channels with colored noise and multiple narrowband interference (2003)

Power line communication (PLC) uses the highly developed infrastructure of the electrical energy distribution network for data transmission. Measurements are showing that a broadband use of PLC channels is possible. So, PLC is of interest to future broadband communication systems. Such systems will be heterogeneous in several respects, for example relative to the used transmission channel but also relative to the complexity of the participant nodes. Wittneben and Kuhn (see block VTC 2002 - Spring) presented a new class of space-time block codes for radio channels. These codes meet the requirements of future communication systems. They are highly flexible and can be adapted to the particular requests of the transmission. In this paper a PLC application of these codes is investigated. They are used as a basis for a scalable and efficient PLC channel coding scheme. This shows that this class of codes can be used as a generic coding scheme for heterogeneous networks. Alternatively, the PLC application can be considered as an example of the usage of the codes on a frequency selective channel with coloured noise. The applied linear block code optimally uses the diversity of the frequency selective channels in combination with OFDM. This leads to significant gains in performance in case of very frequency selective channels; for barely frequency selective channels or for an AWGN channel the performance is slightly better or not affected respectively. These performance results are presented for measured PLC channels.
Concurrent Synthesis of High‐Performance Monolayer Transition Metal Disulfides (2017)

To date, the chemical vapor deposition (CVD) approach has been widely used for the growth of transition metal dichalcogenides (TMDs). However, the reported CVD methods to synthesize TMDs cannot be used to grow more than one type of TMDs. This work reports a promising CVD technique to concurrently synthesize multiple monolayer transition metal disulfides once. The optoelectrical characterization and high‐resolution transmission electron microscopy show the high quality of monolayer crystals, and, more importantly, there is no mixing between different precursors during the growth process, which has been investigated by considering the gas flow dynamics and concentration distribution of precursors in our setup. This strategy indicates the promising future for the batch production of 2D materials and the concurrent synthesis techniques in standard state‐of‐the‐art complementary metal‐oxide‐semiconductor (CMOS) fabrication technology.
Scaffolding Middle School Students’ Construction of Scientific Explanations: Comparing a cognitive versus a metacognitive evaluation approach (2014)

This study investigated the effects of scaffolds as cognitive prompts and as metacognitive evaluation on seventh-grade students' growth of content knowledge and construction of scientific explanations in five inquiry-based biology activities. Students' scores on multiple-choice pretest and posttest and worksheets for five inquiry-based activities were analyzed. The results show that the students' content knowledge in all conditions significantly increased from the pretest to posttest. Incorporating cognitive prompts with the explanation scaffolds better facilitated knowledge integration and resulted in greater learning gains of content knowledge and better quality evidence and reasoning. The metacognitive evaluation instruction improved all explanation components, especially claims and reasoning. This metacognitive approach also significantly reduced students' over- or underestimation during peer-evaluation by refining their internal standards for the quality of scientific explanations. The ability to accurately evaluate the quality of explanations was strongly associated with better performance on explanation construction. The cognitive prompts and metacognitive evaluation instruction address different aspects of the challenges faced by the students, and show different effects on the enhancement of content knowledge and the quality of scientific explanations. Future directions and suggestions are provided for improving the design of the scaffolds to facilitate the construction of scientific explanations.
DIRECT EHRLICH ASCITES TUMOUR CELL DIAMETER MEASUREMENTS BY PROJECTION OF A MICROSCOPE IMAGE (1963)

SYNOPSIS The carcinostatic action of phenazine‐di‐ N ‐oxide against the Ehrlich tumour was subjected to closer study on individual cells. A method was devised whereby the increase in cell diameter could be followed by direct measurement on the projected microscope image. After standardization of the optics so that 1 μ on the slide equalled 1 mm on the ruler, 50 cells per 20 minutes could be measured randomly. Observations 24 hours after drug administration into a mouse bearing a 7‐day tumour showed that treated cell diameters increased from a median diameter of 14 μ to a median of 21 μ (many had doubled in size) as compared to an increase of 1.9 μ in the controls. After 72 hours the treated cells reached a maximum diameter and disintegrated. By this time there was an absence of ascitic fluid. The drug acted by accelerating the growth and exaggerating the disordered mitoses of the tumour cells which were unable to cleave daughter cells, leaving a cluster of partially divided protuberances.
Naturally processed and concealed HLA-A2.1 restricted epitopes from tumor associated antigen tyrosinase-related protein-2 (2000)

Noppen, Christoph Ph.D.; Remmel, Eugenia M.D.; Zajac, Paul Ph.D.; Harder, Felix M.D.; Spagnoli, Giulio C M.D.; Heberer, Michael M.D. Author Information
Apollo: Near-Duplicate Detection for Job Ads in the Online Recruitment Domain (2017)

Job ad data has become an essential part of the recruiting world, helping recruiters to construct views of the labor market to determine emerging skills, closest competitors, and where to get the most value for each recruiting dollar spent. Collecting this data, however, can be problematic, as job ads are posted redundantly at numerous online locations. In this paper, we detail a domain-specific near-duplicate detection methodology aimed at tackling this problem. More specifically, we discuss Apollo, a near-duplicate detection system for job ads. Apollo is in production at CareerBuilder, a large online recruitment company and powers many downstream analytics applications. Its effectiveness, predicated on precision, recall, F-score, and run time, is then compared against other industry-standard deduplication methods to prove its viability over existing paradigms.
Selective Alum Recovery From Clarifier Sludge (1992)

Hoping to save money and to reduce solid waste, water utilities are evaluating various alternatives for the disposal of clarifier sludge containing 30 to 50 percent hydrated aluminum hydroxide. In this work, the authors studied a selective, simple‐to‐operate alum recovery process using composite membranes made of fine particles of chelating polymers entrapped in thin sheets of porous polytetrafluoroethylene. Laboratory studies using the sludge from the Allentown (Pa.) Water Treatment Plant showed that alum can be recovered selectively without any significant carryover of organic matter (trihalomethane precursors), manganese, or other heavy metals into the recovered alum. The composite membrane was quite robust and durable and exhibited a high affinity toward dissolved aluminum.
Power scaling of high-power fiber lasers and amplifiers (2005)

Rare-earth-doped fibers have established themselves as an attractive and power-scalable solid-state laser concept. Using step-index large-mode-area fibers in continuous-wave operation, output powers approaching the kW regime with diffraction-limited beam quality have been demonstrated. In the pulsed regime, average powers on the order of 100 W even for femtosecond fiber laser systems have been reported. Thermo-optical and nonlinear effects within the fiber itself limit the linear power scaling of these systems. Microstructuring the fiber adds several useful features to the fiber for overcoming these restrictions. We review the advantages of rare-earth-doped photonic-crystal fibers for the power scaling of fiber lasers to the multi-kW range with excellent beam quality. The application of the techniques of coherent and incoherent beam combining of fiber lasers and amplifiers for further power scaling are discussed.
Two minimal Tat translocases in <i>Bacillus</i> (2004)

Summary Activity of the Tat machinery for protein transport across the inner membrane of Escherichia coli and the chloroplast thylakoidal membrane requires the presence of three membrane proteins: TatA, TatB and TatC. Here, we show that the Tat machinery of the Gram‐positive bacterium Bacillus subtilis is very different because it contains at least two minimal Tat translocases, each composed of one specific TatA and one specific TatC component. A third, TatB‐like component is apparently not required. This implies that TatA proteins of B. subtilis perform the functions of both TatA and TatB of E. coli and thylakoids. Notably, the two B. subtilis translocases named TatAdCd and TatAyCy both function as individual, substrate‐specific translocases for the twin‐arginine preproteins PhoD and YwbN, respectively. Importantly, these minimal TatAC translocases of B. subtilis are representative for the Tat machinery of the vast majority of Gram‐positive bacteria, Streptomycetes being the only known exception with TatABC translocases.
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice (2012)

Itch, also known as pruritus, is a common, intractable symptom of several skin diseases, such as atopic dermatitis and xerosis. TLRs mediate innate immunity and regulate neuropathic pain, but their roles in pruritus are elusive. Here, we report that scratching behaviors induced by histamine-dependent and -independent pruritogens are markedly reduced in mice lacking the Tlr3 gene. TLR3 is expressed mainly by small-sized primary sensory neurons in dorsal root ganglions (DRGs) that coexpress the itch signaling pathway components transient receptor potential subtype V1 and gastrin-releasing peptide. Notably, we found that treatment with a TLR3 agonist induces inward currents and action potentials in DRG neurons and elicited scratching in WT mice but not Tlr3(-/-) mice. Furthermore, excitatory synaptic transmission in spinal cord slices and long-term potentiation in the intact spinal cord were impaired in Tlr3(-/-) mice but not Tlr7(-/-) mice. Consequently, central sensitization-driven pain hypersensitivity, but not acute pain, was impaired in Tlr3(-/-) mice. In addition, TLR3 knockdown in DRGs also attenuated pruritus in WT mice. Finally, chronic itch in a dry skin condition was substantially reduced in Tlr3(-/-) mice. Our findings demonstrate a critical role of TLR3 in regulating sensory neuronal excitability, spinal cord synaptic transmission, and central sensitization. TLR3 may serve as a new target for developing anti-itch treatment.
SUPPRESSION OF THE INDUCTION OF DELAYED‐TYPE HYPERSENSITIVITY REACTIONS IN MICE BY A SINGLE EXPOSURE TO ULTRAVIOLET RADIATION (1986)

Abstract— After a single exposure of mice to UV radiation, their ability to generate a contact hypersensitivity (CHS) response to contact sensitizers applied epicutaneously to distant, unirradiated skin is severely impaired. It is not clear, however, if the classic delayed type hypersensitivity (DTH) reponse to exogenous antigens, injected into the subcutaneous (s.c.) space, can also be modulated by UV radiation. We report here that a single exposure of mice to UV radiation suppressed the induction of DTH to both erythrocyte and soluble protein antigens injected s.c., but did not suppress the elicitation of the response. The suppressive effect was abrogated by cyclophosphamide treatment. In addition, antigen‐specific suppressor cells were found in the spleens of the mice with a decreased DTH response. Since the ability to mount a DTH response has been linked with the resistance to certain pathogenic microorganisms, we suggest that the suppression of DTH by UV radiation may have the potential to compromise host resistance to such infectious agents.
The cleanability of stainless steel used as a food contact surface: an updated short review. (2010)

The effect of surface roughness on the cleanability of stainless steel as used in the food<br/>industry.
Pentamidine Inhibition of Group I Intron Splicing in <i>Candida albicans</i> Correlates with Growth Inhibition (2000)

We previously demonstrated that pentamidine, which has been clinically used against Pneumocystis carinii, inhibits in vitro a group I intron ribozyme from that organism. Another fungal pathogen, Candida albicans, also harbors a group I intron ribozyme (Ca.LSU) in the essential rRNA genes in almost half of the clinical isolates analyzed. To determine whether pentamidine inhibits Ca.LSU in vitro and in cells, phylogenetically closely related intron-containing (4-1) and intronless (62-1) strains were studied. Splicing in vitro of the Ca.LSU group I intron ribozyme was completely inhibited by pentamidine at 200 microM. On rich glucose medium, the intron-containing strain was more sensitive to growth inhibition by pentamidine than was the intronless strain, as measured by disk or broth microdilution assays. On rich glycerol medium, they were equally susceptible to pentamidine. At pentamidine levels selectively inhibiting the intron-containing strain (1 microM) in glucose liquid cultures, inhibition of splicing and rRNA maturation was detected by quantitative reverse transcription-PCR within 1 min with a 10- to 15-fold accumulation of precursor rRNA. No comparable effect was seen in the intronless strain. These results correlate the cellular splicing inhibition of Ca.LSU with the growth inhibition of strain 4-1 harboring Ca.LSU. Broth microdilution assays of 13 Candida strains showed that intron-containing strains were generally more susceptible to pentamidine than the intronless strains. Our data suggest that ribozymes found in pathogenic microorganisms but absent in mammals may be targets for antimicrobial therapy.
Health Monitoring for Elderly: An Application Using Case-Based Reasoning and Cluster Analysis (2013)

This paper presents a framework to process and analyze data from a pulse oximeter which remotely measures pulse rate and blood oxygen saturation from a set of individuals. Using case-based reasoning (CBR) as the backbone to the framework, records are analyzed and categorized according to their similarity. Record collection has been performed using a personalized health profiling approach in which participants wore a pulse oximeter sensor for a fixed period of time and performed specific activities for pre-determined intervals. Using a variety of feature extraction methods in time, frequency, and time-frequency domains, as well as data processing techniques, the data is fed into a CBR system which retrieves most similar cases and generates an alarm according to the case outcomes. The system has been compared with an expert's classification, and a 90% match is achieved between the expert's and CBR classification. Again, considering the clustered measurements, the CBR approach classifies 93% correctly both for the pulse rate and oxygen saturation. Along with the proposed methodology, this paper provides a basis for which the system can be used in the analysis of continuous health monitoring and can be used as a suitable method in home/remote monitoring systems.
Horizontal gene transfer from transgenic plants to terrestrial bacteria – a rare event? (1998)

Today, 12 years after the first field release of a genetically modified plant (GMP), over 15,000 field trials at different locations have been performed. As new and unique characteristics are frequently introduced into GMPs, risk assessment has to be performed to assess their ecological impact. The possibilities of horizontal gene transfer (HGT; no parent-to-offspring transfer of genes) from plants to microorganisms are frequently evaluated in such risk assessments of GMPs before release into the field. In this review we indicate why putative HGT from plants to terrestrial (soil and plant associated) bacteria has raised concern in biosafety evaluations. Further, we discuss possible pathways of HGT from plants to bacteria, outline the barriers to HGT in bacteria, describe the strategies used to investigate HGT from plants to bacteria and summarize the results obtained. Only a few cases of HGT from eukaryotes such as plants to bacteria have been reported to date. These cases have been ascertained after comparison of DNA sequences between plants and bacteria. Although experimental approaches in both field and laboratory studies have not been able to confirm the occurrence of such HGT to naturally occurring bacteria, recently two studies have shown transfer of marker genes from plants to bacteria based on homologous recombination. The few examples of HGT indicated by DNA sequence comparisons suggest that the frequencies of evolutionarily successful HGT from plants to bacteria may be extremely low. However, this inference is based on a small number of experimental studies and indications found in the literature. Transfer frequencies should not be confounded with the likelihood of environmental implications, since the frequency of HGT is probably only marginally important compared with the selective force acting on the outcome. Attention should therefore be focused on enhancing the understanding of selection processes in natural environments. Only an accurate understanding of these selective events will allow the prediction of possible consequences of novel genes following their introduction into open environments.