gebhart/patrepeval huggingface dataset:
Toward Silent-Speech Control of Consumer Wearables (2015)

Systems that recognize silent speech can enable fast, hands-free communication. Two prototypes let users control Google Glass with tongue movements and jaw gestures, requiring no additional equipment except a tongue-mounted magnet or consumer earphones augmented with embedded proximity sensors.
Use of the polar coordinates technique to study interactions among professional soccer players (2002)

This paper studies the process of interaction among the members of a soccer team using observational methodology. Data were collected from six matches played by Deportivo La Corua during the 2000-01 season, using the polar coordinates technique to establish the activation or inhibition relationships among team members. This analysis allows the reduction of data from the value Zsum, introduced by Cochran [1] and applied by Sackett Polar coordinates analysis allows the combination of diachronic and synchronic perspectives through the representation of the values obtained as vector modules and angles (polar coordinates). The nature of the interactive relationship, depending on the quadrant in which it is located is represented by the angle, while the degree of significance depends on the vector module (>1.96 at a level of significance of 5%).
Choline acetyltransferase+ lymphocytes regulate endothelial nitric oxide synthase (MUC2P.939) (2015)

Abstract Mammalian blood vessels are innervated by adrenergic neurons that increase blood pressure. The neurotransmitter mechanism is dependent upon norepinephrine that mediates contraction of vascular smooth cells to increase arterial resistance. Vasodilation is mediated by acetylcholine, which lowers blood pressure through a mechanism dependent upon relaxation of vascular smooth muscle cells in response to endothelial release of nitric oxide. Endothelial cells are not innervated by cholinergic neurons, and it was unknown whether acetylcholine release by lymphocytes might modulate blood pressure. Here, we observed lymphocytes expressing choline acetyltransferase (ChAT), the enzyme that catalyzes biosynthesis of acetylcholine, in the blood. Co-culture of ChAThi lymphocytes with endothelial cells significantly increased calcium concentration and phosphorylation of eNOS in endothelial cells (p&lt;0.05 vs. ChATlow lymphocytes). Passive transfer of engineered ChAThi Jurkat T cells resulted in an immediate significant decrease in blood pressure in recipient mice to 83±5 % of baseline, while blood pressure after transfer of ChATlow Jurkat T was 104±4 % of baseline (p=0.02). Pre-treatment with the NO synthesis inhibitor L-NG-monomethyl arginine citrate prevented the blood pressure reduction by ChAThi Jurkat T cells, and blood pressure remained at 98%±5% of baseline in these animals (p=0.21). These findings suggest a novel mechanism of lymphocyte-mediated blood pressure regulation.
Hydrogen atmosphere sintering of cobalt-samarium magnets (1977)

Cobalt-samarium magnets were sintered in hydrogen atmosphere without cracking problems. The furnace atmosphere was purged of hydrogen during cooling to preclude hydride formation. Specimens sintered in hydrogen attained higher densities (P>98%) than those sintered at temperatures up to 40°C higher in argon. The use of the hydrogen atmosphere led to substantially improved magnetic properties. The major improvement was in the magnetic induction. The degree of improvement was greater than could be accounted for by the increased density. A specimen sintered in hydrogen had a higher alignment ratio than one sintered in argon at the same temperature. Magnets sintered in hydrogen showed a pronounced difference in shrinkage behavior compared to those sintered in argon. The ratio of the shrinkage in the preferred magnetic direction to that in the cross-section was greatly reduced in hydrogen. A specimen sintered at 1110°C in hydrogen exhibited preferred grain growth in the magnetic direction.
Vectorizing Cartoon Animations (2009)

We present a system for vectorizing 2D raster format cartoon animations. The output animations are visually flicker free, smaller in file size, and easy to edit. We identify decorative lines separately from colored regions. We use an accurate and semantically meaningful image decomposition algorithm, supporting an arbitrary color model for each region. To ensure temporal coherence in the output, we reconstruct a universal background for all frames and separately extract foreground regions. Simple user-assistance is required to complete the background. Each region and decorative line is vectorized and stored together with their motions from frame to frame. The contributions of this paper are: 1) the new trapped-ball segmentation method, which is fast, supports nonuniformly colored regions, and allows robust region segmentation even in the presence of imperfectly linked region edges, 2) the separate handling of decorative lines as special objects during image decomposition, avoiding results containing multiple short, thin oversegmented regions, and 3) extraction of a single patch-based background for all frames, which provides a basis for consistent, flicker-free animations.
Engineering a genetically encoded competitive inhibitor of the KEAP1–NRF2 interaction via structure-based design and phage display (2015)

In its basal state, KEAP1 binds the transcription factor NRF2 (Kd = 5 nM) and promotes its degradation by ubiquitylation. Changes in the redox environment lead to modification of key cysteines within KEAP1, resulting in NRF2 protein accumulation and the transcription of genes important for restoring the cellular redox state. Using phage display and a computational loop grafting protocol, we engineered a monobody (R1) that is a potent competitive inhibitor of the KEAP1-NRF2 interaction. R1 bound to KEAP1 with a Kd of 300 pM and in human cells freed NRF2 from KEAP1 resulting in activation of the NRF2 promoter. Unlike cysteine-reactive small molecules that lack protein specificity, R1 is a genetically encoded, reversible inhibitor designed specifically for KEAP1. R1 should prove useful for studying the role of the KEAP1-NRF2 interaction in several disease states. The structure-based phage display strategy employed here is a general approach for engineering high-affinity binders that compete with naturally occurring interactions.
Electron Probe Microanalysis as a Tool for Identifying Vermiculite Sources (2004)

Extended abstract of a paper presented at Microscopy and Microanalysis 2004 in Savannah, Georgia, USA, August 1–5, 2004.
Implication of the Tpl2 Kinase in Inflammatory Changes and Insulin Resistance Induced by the Interaction Between Adipocytes and Macrophages (2014)

Adipose tissue inflammation is associated with the development of insulin resistance. In obese adipose tissue, lipopolysaccharides (LPSs) and saturated fatty acids trigger inflammatory factors that mediate a paracrine loop between adipocytes and macrophages. However, the inflammatory signaling proteins underlying this cross talk remain to be identified. The mitogen-activated protein kinase kinase kinase tumor progression locus 2 (Tpl2) is activated by inflammatory stimuli, including LPS, and its expression is up-regulated in obese adipose tissue, but its role in the interaction between adipocytes and macrophages remains ill-defined. To assess the implication of Tpl2 in the cross talk between these 2 cell types, we used coculture system and conditioned medium (CM) from macrophages. Pharmacological inhibition of Tpl2 in the coculture markedly reduced lipolysis and cytokine production and prevented the decrease in adipocyte insulin signaling. Tpl2 knockdown in cocultured adipocytes reduced lipolysis but had a weak effect on cytokine production and did not prevent the alteration of insulin signaling. By contrast, Tpl2 silencing in cocultured macrophages resulted in a marked inhibition of cytokine production and prevented the alteration of adipocyte insulin signaling. Further, when Tpl2 was inhibited in LPS-activated macrophages, the produced CM did not alter adipocyte insulin signaling and did not induce an inflammatory response in adipocytes. By contrast, Tpl2 silencing in adipocytes did not prevent the deleterious effects of a CM from LPS-activated macrophages. Together, these data establish that Tpl2, mainly in macrophages, is involved in the cross talk between adipocytes and macrophages that promotes inflammatory changes and alteration of insulin signaling in adipocytes.
Microwave‐assisted extraction of rutin and quercetin from the stalks of <i>Euonymus alatus</i> (Thunb.) Sieb (2008)

The results showed that MAE can be used as an efficient and rapid method for the extraction of the active components from plants.
SLA-Aware Provisioning for Revenue Maximization in Telecom Mesh Networks (2008)

Service level agreement (SLA) is a contract between the service provider (SP) and the customer. Among various parameters, SLA imposes penalties on the SP when the customer's quality-of-service (QoS) requirements are violated. Hence, it is desirable to avoid SLA violations and such penalties. SLA also states the maximum amount of downtime a connection may tolerate during its lifetime. In this study, we present a dynamic provisioning scheme called Preemption-Oriented SLA-Aware Provisioning (POSAP) for telecom mesh networks, which considers a connection's (1) availability requirements, (2) penalty, and (3) state. In addition to the connection's various parameters (availability, penalty, etc.), the amount of affordable downtime is used as a metric to determine the risk of violating the connection's SLA, and hence, its priority. Connection's priority is denoted by urgency level. Our scheme allows resource preemption among connections, i.e., high-priority connections may preempt backup resources from low-priority connections. Also, new connection requests may preempt resources from existing connections. Urgency level determines how resources can be preempted. Our scheme is applied to a US-wide network. Our results show the improved performance in terms of (1) reduced SLA violations, (2) increased network utilization, and (3) increased network revenue, compared to a dedicated primary-backup (P-B) scheme.
Bioresorbable carbonated hydroxyapatite Ca10−xNax(PO4)6−x(CO3)x(OH)2 powders for bioactive materials preparation (2009)

Abstract The purpose of this work was to find and investigate a correlation between the carbonate ion content in crystalline lattice and defect structure, and solubility of the materials; finally, to prepare the materials under study for in vitro tests. Various techniques, such as XRD, FTIR, TEM, FESEM/EDX, TG/DTA, AES (ICP), wet chemical analysis, Ca-ionometry, microvolumetric analysis of evolved CO2, BET adsorption, were applied to determine the efficiency of carbonate substitution, and to quantify the elemental composition, as well as to characterize the structure of the carbonated hydroxyapatite and the site(s) of carbonate substitution,. It was shown that AB-type substitution prevails over other types with the carbonate content increase. According to in vitro tests, the bioactivity of the samples is correlated with the carbonate content in carbonate-doped hydroxyapatite due to accumulation of defects in carbonated hydroxyapatite nanocrystals.
Angiogenesis in ovarian carcinoma (1997)

Angiogenesis is an important independent biomarker for analysis of the risk of recurrence and death for women with epithelial ovarian carcinoma. Image analysis of stained tumor microvessels provides a quantitative measurement of vessel area. See also pages 2257-62.
Control of Myelination by Specific Patterns of Neural Impulses (1998)

A cell culture preparation equipped with stimulating electrodes was used to investigate whether action potential activity can influence myelination of mouse dorsal root ganglia axons by Schwann cells. Myelination was reduced to one-third of normal by low-frequency impulse activity (0.1 Hz), but higher-frequency stimulation (1 Hz) had no effect. The number of Schwann cells and the ultrastructure of compact myelin were not affected. The frequency of stimulation that inhibited myelination decreased expression of the cell adhesion molecule L1, and stimulation under conditions that prevented the reduction in L1 blocked the effects on myelination. This link between myelination and functional activity in the axon at specific frequencies that change axonal expression of L1 could have important consequences for the structural and functional relationship of myelinating axons.
Exchange Current Densities for Fe(II)-Fe(III) Solutions in Sulfuric Acid and Perchloric Acid (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExchange Current Densities for Fe(II)-Fe(III) Solutions in Sulfuric Acid and Perchloric AcidF. C. AnsonCite this: Anal. Chem. 1961, 33, 7, 939–942Publication Date (Print):June 1, 1961Publication History Published online1 May 2002Published inissue 1 June 1961https://pubs.acs.org/doi/10.1021/ac60175a037https://doi.org/10.1021/ac60175a037research-articleACS PublicationsRequest reuse permissionsArticle Views559Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Interaction of vitamin K dependent proteins with membranes (1978)

The membrane-binding characteristics of six vitamin K dependent plasma proteins, which have homologous amino acid sequences, were compared. All of these proteins display calcium-dependent membrane binding and the identified equilibria for protein-membrane binding are qualitatively the same for all proteins. Quantitative characteristics of these protein-membrane interactions allow organization into distinct subgroups. Protein C and factor VII form a subgroup which has extemely low affinity for bilayer membranes; prothrombin, factor X, and protein S form the tightest complexes with membranes and factor IX displays intermediate affinity. In the presence of manganese (which substitutes for calcium in a cation-dependent protein transition), calcium titration of protein-membrane binding shows the same calcium dependence for all proteins except prothrombin which requires lower calcium. These protein-membrane binding characteristics agree very well with the relatedness of these proteins based on their partial amino-terminal sequences.
Evaluation of Auditory and Visual Feedback on Task Performance in a Virtual Assembly Environment (2006)

This paper presents the creation of an assembly simulation environment with multisensory feedback (auditory and visual), and the evaluation of the effects of auditory and visual feedback on the task performance in the context of assembly simulation in a virtual environment (VE). This VE experimental system platform brings together complex technologies such as constraint-based assembly simulation, optical motion tracking technology, and real time 3D sound generation technology around a virtual reality workbench and a common software platform. A peg-in-a-hole and a Sener electronic box assembly task have been used as the task cases to conduct the human factor experiment, using sixteen participants. Both objective performance data (i.e., task completion time, TCT; and human performance error rate, HPER) and subjective opinions (i.e., questionnaires) on the utilization of auditory and visual feedback in a virtual assembly environment (VAE) have been gathered from the experiment. Results showed that the introduction of auditory and/or visual feedback into VAE did improve the assembly task performance. They also indicated that integrated feedback (auditory plus visual) offered better assembly task performance than either feedback used in isolation. Most participants preferred integrated feedback to either individual feedback (auditory or visual) or no feedback. The participants' comments demonstrated that nonrealistic or inappropriate feedback had a negative effect on the task performance, and easily made them frustrated.
Platelet-activating factor causes ventilation-perfusion mismatch in humans. (1994)

We hypothesized that platelet-activating factor (PAF), a potent inflammatory mediator, could induce gas exchange abnormalities in normal humans. To this end, the effect of aerosolized PAF (2 mg/ml solution; 24 micrograms) on ventilation-perfusion (VA/Q) relationships, hemodynamics, and resistance of the respiratory system was studied in 14 healthy, nonatopic, and nonsmoking individuals (23 +/- 1 [SEM]yr) before and at 2, 4, 6, 8, 15, and 45 min after inhalation, and compared to that of inhaled lyso-PAF in 10 other healthy individuals (24 +/- 2 yr). PAF induced, compared to lyso-PAF, immediate leukopenia (P < 0.001) followed by a rebound leukocytosis (P < 0.002), increased minute ventilation (P < 0.05) and resistance of the respiratory system (P < 0.01), and decreased systemic arterial pressure (P < 0.05). Similarly, compared to lyso-PAF, PaO2 showed a trend to fall (by 12.2 +/- 4.3 mmHg, mean +/- SEM maximum change from baseline), and arterial-alveolar O2 gradient increased (by 16.7 +/- 4.3 mmHg) (P < 0.02) after PAF, because of VA/Q mismatch: the dispersion of pulmonary blood flow and that of ventilation increased by 0.45 +/- 0.1 (P < 0.01) and 0.29 +/- 0.1 (P < 0.04), respectively. We conclude that in normal subjects, inhaled PAF results in considerable immediate VA/Q inequality and gas exchange impairment. These results reinforce the notion that PAF may play a major role as a mediator of inflammation in the human lung.
Aktionsforschung - eine neue Methode? (1974)

Im folgenden wollen wir prufen, inwieweit ein solcher Anspruch gerechtfertigt ist. Wir wollen insbesondere prufen, ob und welche Komponenten des Verfahrenskomplexes „Aktionsforschung tatsachlich neu gegenuber dem kritischen Rationalismus sind. Sollten sich neue Aspekte dem kritischen Rationalismus gegenuber aufweisen lassen, wollen wir versuchen, zu klaren, ob damit bestehende Probleme besser gelost werden konnen*).
Novel Use of Bovine Zeta-Crystallin as a Conformational DNA Probe to Characterize a Phase Transition Zone and Terminally Differentiating Fiber Cells in the Adult Canine Ocular Lens. (2001)

Using a novel immunocytochemical staining method, we aimed to characterize the phase transition zone (PTZ) (approximatly 100 microm) in adult ocular lenses and the process of terminal differentiation (denucleation) within normal fiber cells. The binding to DNA of zeta-(zeta) crystallin (Z-DNA-binding protein) and anti-double-stranded (ds-)-B-DNA antibody probes was found to decline gradually throughout denucleating fibers, with a precipitous decrease occurring at about 100 microm (PTZ). Nuclei of superficial fiber cells (in front of the PTZ) showed the highest DNA probe-binding values, followed by middle fibers (MF) and deep fibers (DF). With the use of zeta-crystallin, anti-ds-B-DNA antibody, and anti-single stranded (ss-) DNA antibody probes, it was possible to reveal a loss of reactivity of fiber cell ds-DNA. Ss-DNA antibody binding was seen initially in the MF and reached its highest intensity level in the DF. The pattern of zeta-crystallin probe-DNA reactivity correlates with the loss of anti-B-DNA antibody staining and decreased eosin-protein staining. These data suggest that a reorganization of DNA and intracellular protein supramolecular order in normal adult lenses occurs at a depth of about 100 microm (PTZ).
Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats (1993)

Bacterial lipopolysaccharide (LPS) is the toxic moiety of the gram-negative bacterial outer membrane which is responsible for many of the pathophysiological events that occur during endotoxic shock. Here we investigate the hypothesis that endogenous glucocorticoids modulate the formation of nitric oxide (NO) and of vasodilator cyclooxygenase metabolites in response to LPS. Intravenous administration of a small dose of Escherichia coli LPS (0.1 mg kg-1) to normal Wistar rats caused a moderate fall in blood pressure, and 120 min of endotoxaemia was not associated with an attenuation of the rise in blood pressure elicited by intravenous injection of noradrenaline (NA; vascular hyporeactivity). When adrenalectomized (ADX) rats, which lack endogenous glucocorticoids, were subjected to the same dose of LPS, they developed a much more severe form of circulatory shock, which was characterized by a profound fall in blood pressure and a vascular hyporeactivity to NA. Both hypotension and vascular hyporeactivity were prevented by pre-treatment with dexamethasone. Inhibition of NO biosynthesis with NG-methyl-L-arginine significantly attenuated the hypotension and the vascular hyporeactivity to NA caused by LPS in ADX rats. Similarly, the cyclooxygenase inhibitor indomethacin significantly attenuated the circulatory failure elicited by LPS in the ADX rats. Interestingly, 120 min of endotoxaemia resulted in a de novo biosynthesis of an induced isoform of NO synthase in the lungs of ADX, but not normal Wistar, rats. This induction of NO synthase was prevented by dexamethasone pre-treatment.(ABSTRACT TRUNCATED AT 250 WORDS)
The total contact cast: a method for treating neuropathic diabetic ulcers. (1997)

Plantar ulcers that do not heal in patients with diabetes and peripheral sensory neuropathy have been shown to be precursors of lower extremity amputation. The total contact cast is considered by many authorities to be the most effective technique for healing of wounds in the neuropathic extremity, yet it still is not widely used in clinical practice. Use of the total contact cast allows mobilization and results in diminished edema and decreased pressure over the ulcerated area. Complete healing usually occurs in eight weeks or less. Total contact casting with careful follow-up should be considered as a useful modality for healing plantar ulcers in diabetic patients with neuropathy of the extremities.
Serum Intercellular Adhesion Molecule-1 and Long-Term Response to IFN-α2b Therapy in Chronic Hepatitis C (1998)

We have attempted to correlate the outcome of interferon (IFN) therapy with circulating soluble intercellular adhesion molecule-1 (sICAM-1) and the level of viremia in a sample of patients with chronic hepatitis C virus (HCV) infection. Forty-two patients were studied. Eighteen patients were maintained in long-term remission following IFN therapy, whereas 24 did not respond or relapsed. Serum concentrations of sICAM-1 were measured by enzyme-linked immunoassay. Viremia was measured by branched DNA signal amplification assay. Basal sICAM-1 was significantly higher in long-term responders than in nonresponder/relapsing patients. It was found that very high levels (>1000 ng/ml) were closely associated with long-term clinical response. A quantitative evaluation of viremia in basal conditions, which was significantly lower in long-term responders, gave completely opposite results. During treatment, sICAM-1 concentrations significantly decreased in the group of long-term responders but not in the nonresponders. sICAM-1 reduction was apparent as early as 1 month after treatment started. Serum sICAM-1 may be a useful parameter in evaluating the outcome of patients with chronic hepatitis C infection treated with IFN.