gebhart/patrepeval huggingface dataset:
A meristem-related gene from tomato encodes a dUTPase: analysis of expression in vegetative and floral meristems. (1992)

A meristem-specific gene coding for deoxyuridine triphosphatase (EC 3.6.1.23) (dUTPase) in tomato was isolated, and its developmental expression in vegetative and floral apices was monitored. An 18-kD polypeptide, P18, was isolated as a consequence of its accumulation in arrested floral meristems of anantha mutant plants. The corresponding cDNA isolated from an expression library exhibited a 40 to 60% similarity with the pseudoprotease sequences of poxviruses, genes that have been suggested to encode dUTPases. Enzymatic tests and conservation of peptide motifs common to bacterial and viral genes verified that the P18 cDNA clone indeed represents a eukaryotic dUTPase. Immunogold localization and in situ hybridization experiments showed that polypeptides and transcripts of dUTPase are maintained at high levels in apical meristematic cells of vegetative and floral meristems. dUTPase gene activity is also high in the potentially meristematic cells of the provascular and vascular system. Its expression is lower in the immediate parenchymal derivatives of the apical meristematic cells, and this downregulation marks, perhaps, the transition from totipotency to the first differentiated state.
Lens Disorders: A Clinical Manual of Cataract Diagnosis (1998)

Early studies of the lens Development of the lens Lens growth Lens structure Accomodation and presbyopia Biology of the lens and lens transparency Examination of the lens Lens malformations and displacements Biology of cataract Forms of cataract Aetiology of cataract - infantile, inherited and systemic causes Aetiology of cataract - ocular, toxic, nutritional and physical factors Cataract progress and prognosis Vision in cataract.
The Reaction of GaP(s) with H[sub 2]O(g) and the Range of Stability of GaP(s) under Pressures of Ga[sub 2]O and P2 (1964)

The reaction of with wet hydrogen has been studied by a vapor transport method. Experimental equilibrium constants in the temperature range of 800°–1100°C have been found to be in satisfactory agreement with the equilibrium constants calculated from the free energies of formation of the reacting components, , , and . A heat of formation of at 298°K of −42.75 kcal/mole has been obtained from the Knudsen cell measurements of Johnston. A value of for of 14.4 cal/deg mole has also been obtained. The range of pressures of and P2 over which is stable is described. Formation of both and is considered. Variation in the solubility of oxygen in as a function of the pressures of and P2 is discussed.
Direct torque control of asynchronous motor based on space vector modulation (2011)

In conventional direct torque control (DTC) strategy, the inverter switching frequency is not fixed, torque ripple and total current harmonic distortion is high. In order to overcome these problems, improved DTC using space vector pulse width modulation strategy (SVPWM-DTC) is proposed in this paper. Switching table is replaced by SVPWM module to enable the fixed switching frequency. On the other hand, PI controllers are used to regulate the stator flux and torque errors. The simulation results verify the system is accuracy and feasibility.
Measurement of Radiation-Induced Interface Traps Using MOSFETs (1984)

The buildup of SiO2-Si interface traps due to radiation was measured by a charge pumping measurement method and by a technique based on the slope of the transistor ln(Id)-Vg characteristics in weak inversion. Both aueasurements make use of MOS transistors. The important differences in the "trap density" obtained from the two measurement methods are discussed. The results of the measurements are interpreted to assess the effect of gamma irradiation on the distribution of interface trap density.
Specific inhibitors of eukaryotic DNA synthesis and DNA polymerase α, 3-deoxyaphidicolin and aphidicolin-17-monoacetate (1983)

Of several phytotoxins isolated from culture filtrates of Phoma betae Frank PS-13, an incitant of leaf spot disease of sugar beet, three have been identified as aphidicolin, 3-deoxyaphidicolin and aphidicolin-17-monoacetate. Aphidicolin is a selective inhibitor of eukaryotic DNA polymerase alpha (Ikegami et al. (1978) Nature 275, 458-460). Consequently, we studied the action mechanism of 3-deoxyaphidicolin and aphidicolin-17-monoacetate. These aphidicolin analogues markedly inhibited the in vivo DNA synthesis of sea urchin embryos and HeLa cells but not RNA and protein syntheses. Only DNA polymerase alpha, not DNA polymerase beta and gamma, was inhibited by these drugs. The mode of action of these analogues on DNA polymerase alpha from the sea urchin was competitive inhibition with respect to dCTP with Ki values of 0.44 micrograms/ml for deoxyaphidicolin and 0.89 micrograms/ml for aphidicolin monoacetate, respectively. None of the other three dNTPs competed with these drugs. A similar inhibitory mode was observed using the enzyme from HeLa cells and toad oocytes. These drugs at a concentration of 2 micrograms/ml caused a delay in the cleavage of fertilized eggs of the sea urchin and decomposition before blastulation, indicating the possibility of achromosomal cleavage because of the absence of DNA synthesis. Based on the above, it is concluded that these analogues can be used as other inhibitors of eukaryotic DNA synthesis and DNA polymerase alpha.
Viscometric evidence of interactions between hydrophobically modified poly(sodium acrylate) and sodium dodecyl sulfate (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTViscometric evidence of interactions between hydrophobically modified poly(sodium acrylate) and sodium dodecyl sulfateI. Iliopoulos, T. K. Wang, and R. AudebertCite this: Langmuir 1991, 7, 4, 617–619Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April 1991https://pubs.acs.org/doi/10.1021/la00052a003https://doi.org/10.1021/la00052a003research-articleACS PublicationsRequest reuse permissionsArticle Views749Altmetric-Citations171LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Features And Applications Of A New Self-Frequency-Doubling Laser Crystal - NYAB (1989)

The new crystal of NYAB (neodymium yttrium aluminum borate) is presented. The optical and mechanical properties, crystal structure and growth of this crystal is investigated. Performance of emissions at 1063 nm and 532 nm is presented for both flash-lamp-pumped (pulsed) and dye-laser and diode-laser pumped (cw). A comprehensive model for intracavity doubling including the dopant-dependent gain and absoprtion (loss) is also analyzed. In this paper, we denornstrate the first experimental results of diode-pumped NYAB with green ligth output power in the 10 μW range. © 1989, SPIE.
Automatic orientation determination from Kikuchi patterns (1999)

Some formal aspects of crystal orientation determination from Kikuchi patterns are discussed, with respect to writing general and fast algorithms for automatic indexing of the patterns and orientation determination. The geometry of the problem is presented in a general form which is also suitable for channeling patterns or X-ray Kossel patterns. Moreover, geometrical ambiguities and other reliability issues are considered. Some strategies designed to handle artifacts of automatic pattern analysis are presented. Finally, the reliability and the accuracy of the described procedures and the sensitivity of the results to the errors of the basic measurement parameters were tested on computer-generated patterns.
Occlusion of Grubbs' Catalysts in Active Membranes of Polydimethylsiloxane:  Catalysis in Water and New Functional Group Selectivities (2006)

The Grubbs' first and second generation catalysts were occluded into cross-linked slabs of polydimethylsiloxane with volumes from 1 mm3 to 1 cm3 by swelling the polymer with catalyst and methylene chloride. Methylene chloride was evaporated under vacuum to yield occluded catalysts where their solvent was polydimethylsiloxane. These occluded catalysts were reacted with alkenes dissolved in H2O or H2O/MeOH mixtures that diffused into the polydimethylsiloxane to react by ring-closing metathesis and cross metathesis. Control experiments revealed that the catalysts remained occluded and metathesis did not occur in the solvent. Occlusion of these catalysts allowed commercially available Grubbs' catalysts to be used with H2O as the solvent while isolating the H2O sensitive ruthenium methylidene from exposure to H2O. Functional group selective experiments were carried out where the polydimethylsiloxane was an "active" membrane to exclude salts. Polydimethylsiloxane is a hydrophobic polymer, so the deprotonated salt of diallylmalonic acid did not diffuse into it while a diallylether diffused into it and reacted by metathesis. Thus, by controlling the polarity of reagents their reactivity can be controlled owing to the properties of polydimethylsiloxane rather than those of the Grubbs' catalysts. Occlusion of catalysts in polydimethylsiloxane has been shown to add new selectivities to mature catalysts.
Tunable GaAs Laser in an External Dispersive Cavity (1972)

Tunability of the cw radiation from a GaAs injection laser in an external dispersive cavity was achieved over a range of 150 Å about a center wavelength of 8525 Å at 77°K. The emitted radiation was analyzed with a Fabry-Perot etalon. Under certain conditions single-mode operation with cw output power as large as 17 mW was observed. Half-width of such modes was estimated to be less than 350 MHz.
Deficiency in the anti‐aging gene Klotho promotes aortic valve fibrosis through <scp>AMPK</scp> α‐mediated activation of <scp>RUNX</scp> 2 (2016)

Fibrotic aortic valve disease (FAVD) is an important cause of aortic stenosis, yet currently there is no effective treatment for FAVD due to its unknown etiology. The purpose of this study was to investigate whether deficiency in the anti-aging Klotho gene (KL) promotes high-fat-diet-induced FAVD and to explore the underlying molecular mechanism. Heterozygous Klotho-deficient (KL(+/-) ) mice and WT littermates were fed with a high-fat diet (HFD) or normal diet for 13 weeks, followed by treatment with the AMPKα activator (AICAR) for an additional 2 weeks. A HFD caused a greater increase in collagen levels in the aortic valves of KL(+/-) mice than of WT mice, indicating that Klotho deficiency promotes HFD-induced aortic valve fibrosis (AVF). AMPKα activity (pAMPKα) was decreased, while protein expression of collagen I and RUNX2 was increased in the aortic valves of KL(+/-) mice fed with a HFD. Treatment with AICAR markedly attenuated HFD-induced AVF in KL(+/-) mice. AICAR not only abolished the downregulation of pAMPKα but also eliminated the upregulation of collagen I and RUNX2 in the aortic valves of KL(+/-) mice fed with HFD. In cultured porcine aortic valve interstitial cells, Klotho-deficient serum plus cholesterol increased RUNX2 and collagen I protein expression, which were attenuated by activation of AMPKα by AICAR. Interestingly, silencing of RUNX2 abolished the stimulatory effect of Klotho deficiency on cholesterol-induced upregulation of matrix proteins, including collagen I and osteocalcin. In conclusion, Klotho gene deficiency promotes HFD-induced fibrosis in aortic valves, likely through the AMPKα-RUNX2 pathway.
Flupirtine in the treatment of post-operative pain. (1987)

Flupirtine maleate (referred to throughout this paper as flupirtine) capsules 100 mg and suppositories 150 mg were found to be safe and efficacious in several randomized, controlled, double-blind parallel group clinical trials. 586 patients (40 children) suffering from post-operative pain were treated. Flupirtine was significantly more effective than placebo and as well tolerated. It was as effective and acceptable as pentazocine and dihydrocodeine for the treatment of post-operative pain, but offered advantages in terms of fewer central nervous system side effects. It was at least as effective as the non-narcotics metamizole, paracetamol and naproxen.
Simultaneous ranging and remote sensing utilizing chirped laser dispersion spectroscopy (2014)

Simultaneous ranging and laser-spectroscopic gas-sensing is demonstrated for the first time with a non-pulsed sensing technique. Besides remote sensing, spectroscopy with highly multi-mode cells will become calibration-free. Extension to a simultaneous multi-path measurement is possible.
Invenio v2.0: A Pythonic Framework for Large-Scale Digital Libraries (2014)

Presentation at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014
Transdifferentiation of Distal but Not Proximal Tubular Epithelial Cells from Human Kidney in Culture (1999)

Human renal proximal and distal (thick ascending limb and early distal convoluted tubule) epithelial cells have been isolated according to their specific antigen expression. The cells were well characterized by flow cytometry, enzyme cytochemistry and electron microscopy and cultured for up to 3 months. Cultured tubular cells coexpressed cytokeratin and vimentin as intermediate filament proteins. While primary isolated cells, proximal as well as distal, revealed the phenotypic characteristics of their nephron origin, cultured distal cells showed the tendency to dedifferentiate/transdifferentiate. Distal cells lost their characteristic expression of Tamm-Horsfall glycoprotein and started de novo expression of the proximal marker proteins aminopeptidase M, gamma-glutamyl transferase and dipeptidyl peptidase IV. The expression of these antigens by distal cells could be shown by flow-cytometric analysis and fluorescence microscopy. Enzyme activity assays revealed the activity of aminopeptidase M, gamma-glutamyl transferase and dipeptidyl peptidase IV, but not of the proximal marker enzyme alkaline phosphatase. This antigenic shift could not be prevented in different culture media, and the original phenotype could not be restored. Cultured cells displayed characteristic hormonal stimulation patterns indicative of their proximal and distal origins, as shown by activation of adenylate cyclase by different peptide hormones. These results indicate that distal tubular cells possibly transdifferentiate to a more proximal phenotype in view of loss of the distal marker enzyme Tamm-Horsfall protein and de novo expression of proximal marker enzymes like dipeptidyl peptidase IV and aminopeptidase M.
The case for a worldwide ban on smoking in public places (2010)

Banning smoking in public places is an effective tool for reducing tobacco-related morbidity across a multiplicity of diseases. Countries that have not already done so should introduce legislation to enforce effective legislation that prohibits smoking in public places.
Liquid Quenched Superconductor Ba-Y-Cu-O with T<sub>c,zero</sub>=88 K and AC Josephson Effect at 77 K (1987)

A superconducting Ba-Y-Cu-O with T c,zero =88 K was prepared by a liquid quenching method, in which the melt of nominal composition Ba 2 YCu 3 O 7-δ was first quenched and then the sample was annealed at 900°C for 48 h in air. AC Josephson effect was observed at 77 K in point-contacts made of the present samples. This new method is applicable to the preparation of superconducting thin films, wires, tapes and superconduciting cavities.
Efficient Power Allocation in E-MBMS Enabled 4G Networks (2010)

The plethora of mobile multimedia services that are expected to face high penetration, poses the need for the deployment of a resource economic scheme in Long Term Evolution (LTE) networks. To this direction, the Evolved - Multimedia Broadcast / Multicast Service (E-MBMS) is envisaged to play an instrumental role for LTE proliferation and set the basis for a successful 4th Generation (4G) standardization process. One of the most critical aspects of E-MBMS performance is the selection of the most efficient radio bearer, in terms of power consumption. This chapter presents the prevailing radio bearer selection mechanisms and examines their performance in terms of power consumption. Furthermore, it discusses problems regarding the high power requirements for the realization of E-MBMS and evaluates the proposed techniques/solutions. Finally, this chapter presents a novel mechanism for efficient power control during E-MBMS transmissions that conforms to LTE requirements for simultaneous provision of multiple multimedia sessions.
Propene polymerization with MgCl<sub>2</sub>‐supported catalysts: effects of using a diether as external donor (1997)

Abstract 13 C NMR analysis of poly(propylene) fractions of different tacticity, obtained using a catalyst system of type MgCl 2 /TiCl 4 /diisobutyl phthalate – AlEt 3 – diether, has provided further evidence that the active species in this system are similar to those in which the ether is used as “internal” rather than “external” donor. Chain‐end analysis of relatively low molecular weight polymer fractions indicated, for polymers of similar molecular weight, similar proportions of butyl‐terminated chain‐ends, indicative of chain transfer with hydrogen following regioirregular (2,1‐) insertion. The relatively high hydrogen response of diether‐containing catalyst systems can therefore be largely ascribed to this phenomenon, irrespective of whether the diether is used as internal or external donor. At relatively low hydrogen concentrations, chain transfer to hydrogen takes place predominantly after the occasional secondary insertion, while the additional presence of vinylidene chain‐ends in certain xylene‐soluble fractions indicates that chain transfer via β‐H transfer takes place mainly after primary insertion.
The purification and properties of the lectin from potato tubers, a hydroxyproline-containing glycoprotein (1973)

1. Potato lectin has been purified and shown to be a glycoprotein containing about 50% of carbohydrate. Most of the sugar residues (92%) are arabinose; small amounts of galactose, glucose and glucosamine are also present. 2. The most abundant amino acid is hydroxyproline (16% of the residues), 11.5% of the residues are half-cystine and phenylalanine is absent. The lectin also contains about one residue/molecule of a basic amino acid, not usually found in proteins, which has been tentatively identified as ornithine. There is indirect evidence that the components of the glycoprotein are linked through hydroxyproline and arabinose. 3. By gel filtration in 6m-guanidine-HCl on Sepharose 4B, it was found that both the native glycoprotein and its S-carboxymethylated derivative had subunit molecular weights of 46000 (+/-5000). In a non-denaturing solution, two of these units appear to be associated. 4. The lectin is specifically inhibited in its agglutination reaction by oligosaccharides that contain N-acetylglucosamine. Its specificity is similar to, but not identical with, that of wheat-germ agglutinin.
Platelets inhibit antigen presentation by dendritic cells and tumor cells. (2010)

This study was aimed to investigate the effects of intact platelets on antigen presentation by either tumor cells or bone-marrow derived dendritic cells (BMDCs). The antigen presentation assay models included BMDC stimulated mixed allogenic lymphocyte reaction and antigen presentation by OVA-harboring EG7 cells to OVA-specific TCR transgenic OT-I T lymphocytes. Fresh platelets prepared from hemogenic murine bloods were added to the culture systems to different levels. Lymphocyte proliferation, level of secreted cytokines in the culture and phenotype of BMDCs were measured by isotope incorporation, ELISA and flow cytometry respectively. The results indicated that when platelets at certain concentrations were added in co-culture system containing both OVA-harboring EG7 cells and OVA-specific TCR transgenic OT-I T lymphocytes, both lymphocyte proliferation and IFNγ production were inhibited. The addition of platelets to the BMDC culture followed by LPS or CpG ODN treatment blocked B7-2 upregulation, cytokine production of the BMDCs, and stimulation potency of such BMDCs for allogenic lymphocytes. Furthermore, platelets inhibited the ability of BMDCs to present both soluble and cellular antigens to clonal specific T lymphocytes, which reflected by decreased lymphocyte proliferation and cytokine production. All these platelet-dependent effects were related to the concentrations of platelets in culture. FACS analysis also revealed that platelets bound to BMDCs induced slightly higher cell death rate of BMDCs. It is concluded that under certain conditions, platelets may affect antigen presentation and the overall outcome of immune responses in a negative way, providing new evidence for the hypothesis that platelets play much more complicated roles in the regulation of immune compartments than originally believed.
Conte*t clones or re-thinking clone on a call graph (2012)

To improve clone-detection methods and to enable new analysis methods with clone detection, e.g., to detect a wider range of bad smells and anti-patterns, this paper introduces a concept context clone, in a form comparable to the (traditional) content clone. A context clone is based on the similarity of the contexts in which code fragment is used, instead of the similarity of the code fragments themselves. This paper includes an explanation of context clones, research questions about the context clone, expected use of the context clone in a mixed way with the content clone, and an actual example of a context clone with a prototype tool.
Listeria monocytogenes serovar 4b strains divided into two groups using polymerase chain reaction (PCR) and restriction enzyme analysis (REA) (1995)

Listeria monocytogenes serovar 4b strains divided into two groups using polymerase chain reaction (PCR) and restriction enzyme analysis (REA)
Antioxidative Effect of Extracts from Erodium cicutarium L. (1994)

Extracts from Erodium cicutarium L. (EC) and some standard substances present in EC extracts were tested for their antioxidative properties during Fe(2+)-induced triglyceride oxidation. Hydrophobic fractions such as petroleum ether (PEE), benzene (BE) and chloroform I (ChE I) extracts as well as hydrophilic fractions i.e. water (WE) and ethyl acetate (EAE) showed an antioxidative effect. Among the tested substances vitamin C and some polyphenolic compounds: tannin, (+)-catechin and gallic acid exhibited antioxidative activity, stronger than the one of the mentioned extracts.
A Novel Method for Relative Quantitation of N-Glycans by Isotopic Labeling Using 18O-Water (2014)

Quantitation is an essential aspect of comprehensive glycomics study. Here, a novel isotopic-labeling method is described for N-glycan quantitation using (18)O-water. The incorporation of the (18)O-labeling into the reducing end of N-glycans is simply and efficiently achieved during peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase F release. This process provides a 2-Da mass difference compared with the N-glycans released in (16)O-water. A mathematical calculation method was also developed to determine the (18)O/(16)O ratios from isotopic peaks. Application of this method to several standard glycoprotein mixtures and human serum demonstrated that this method can facilitate the relative quantitation of N-glycans over a linear dynamic range of two orders, with high accuracy and reproducibility.