gebhart/patrepeval huggingface dataset:
A Novel Dark-Inducible Protein, LeDI-2, and Its Involvement in Root-Specific Secondary Metabolism in<i>Lithospermum erythrorhizon</i>  (2001)

Lithospermum erythrorhizon produces red naphthoquinone pigments that are shikonin derivatives. They are accumulated exclusively in the roots of this plant. The biosynthesis of shikonin is strongly inhibited by light, even though other environmental conditions are optimized. Thus, L. erythrorhizon dark-inducible genes (LeDIs) were isolated to investigate the regulatory mechanism of shikonin biosynthesis. LeDI-2, showing the strict dark-specific expression, was further characterized by use of cell suspension cultures and hairy root cultures as model systems. Its mRNA accumulation showed a similar pattern with that of shikonin. In the intact plants LeDI-2 expression was observed solely in the root, and the longitudinal distribution of its mRNA was also in accordance to that of shikonin. LeDI-2 encoded a very hydrophobic polypeptide of 114 amino acids that shared significant similarities with some root-specific polypeptides such as ZRP3 (maize) and RcC3 (rice). Reduction of LeDI-2 expression by its antisense DNA in hairy roots of L. erythrorhizon decreased the shikonin accumulation, whereas other biosynthetic enzymes, e.g. p-hydroxybenzoic acid:geranyltransferase, which catalyzed a critical biosynthetic step, showed similar activity as the wild-type clone. This is the first report of the gene that is involved in production of secondary metabolites without affecting biosynthetic enzyme activities.
Cloud-computing based velocity profile generation for minimum fuel consumption: A dynamic programming based solution (2012)

This paper proposes a new framework to minimize the fuel consumed in a conventional vehicle over a given driving route by finding the optimal velocity profile. The optimization problem is solved in a remote cloud computing environment and assumes the vehicle route to be known a priori. A spatial domain dynamic programming optimization algorithm is used in this study to find the optimal velocity profile. The cloud-computing environment integrates information from GIS, road speed limits, into a vehicle simulator equipped with a fuel consumption model to predict fuel use along the desired route. The resulting global optimal velocity profile is sent back to the driver for velocity advisory.
Polyoxometalate–Reduced Graphene Oxide Hybrid Catalyst: Synthesis, Structure, and Electrochemical Properties (2013)

The deposition of polyoxometalate (POM) on chemically reduced graphene oxide sheets was carried out through electron transfer interaction and electrostatic interaction between POM and graphene sheets to make a heterogeneous catalyst in aqueous media. Well dispersed individual phosphomolybdic acid (PMo) clusters were observed by electron microscopy and atomic force microscopy measurements. The interaction between polyoxometalate and the graphene sheet was confirmed by using various spectroscopic methods such as FT-IR, UV-vis, and Raman. The UV-visible, IR, and cyclic voltammetry results revealed alteration of the electronic structure of deposited PMo as a result of strong interaction with the graphene oxide surface. Electrochemical properties of the PMo-rGO catalyst were investigated in an aqueous acidic electrolyte. The hybrid catalyst showed enhanced electro-oxidation of nitrite compared with pure homogeneous PMo and rGO.
Synthesis of β‐phenylethylamine derivatives X<i>N</i>‐(hydroxy‐ and methoxy‐aralkyl) derivatives (1973)

Abstract The synthesis and some pharmacological properties are described of compounds of the general structure: magnified image The series contains strong and/or selective utero‐relaxing agents. Stereoisomers of two interesting compounds were separated and characterized, and their configurations were established.
How stable are 1,2-dihydro-1,2-azaborines toward water and oxygen? (2009)

The stability of 1,2-dihydro-1,2-azaborines toward oxygen and water was investigated as a function of their ring substituents: while generally 1,2-dihydro-1,2-azaborines are compatible with water, their stability toward oxygen is dependent on the boron and the C(3) substituents, and we found that electron withdrawing groups enhanced the heterocycle's ability to resist oxidative degradation.
Synthesis, Characterization, and Autoreduction of a Highly Electron-Deficient Porphycenatoiron(III) with Trifluoromethyl Substituents (2003)

The synthesis of the first fluorine-containing iron porphycenes, 2,7,12,17-tetraethyl-3,6,13,16-tetrakis(trifluoromethyl)porphycenatoiron(III) chloride [FePc(EtioCF(3))]Cl and its micro-oxo dimer [FePc(EtioCF(3))](2)O and their characterizations are reported. The crystal structure of [FePc(EtioCF(3))](2)O displays a severe saddled distortion of the porphycene framework due to the steric and electronic effects of the CF(3) substituents. The oxidation and reduction potentials for the micro-oxo dimer are significantly more positive compared to those observed for the reference micro-oxo dimer of the iron porphycenes and porphyrins having no electron-withdrawing substituent. Moreover, the (1)H and (19)F NMR spectra of [FePc(EtioCF(3))](2)O demonstrated that the micro-oxo dimer is readily converted into the monomeric ferrous complex in pyridine-d(5) through autoreduction for 1 day, although the reduction of the reference iron porphycenes and porphyrins are not observed in pyridine. These results indicate that the trifluoromethylated iron porphycene is a highly electron-deficient complex with a pyrrolic macrocycle ligand.
A Comparative Study of Vamana & Virechana karma in Ekakushtha w.s.r to Psoriasis (2009)

Psoriasis is a disease which affects the skin and joints It commonly causes red scaly patches to appear on the skin. Psoriasis is a papulo squamous disorder of the skin, characterized by sharply defined erythemato squamous lesions. They vary in size from pinpoint to large plaques.The scaly patches caused by Psoriasis are called Psoriatic plaque. Psoriasis is hypothesized to be immune-mediated and is not contagious. The disorder is a chronic recurring condition which varies in severity from minor localized patches to complete body coverage. The cause of Psoriasis is not known, but it is believed to have a genetic component. Several factors are thought to aggravate psoriasis. These include stress, excessive alcohol consumption and smoking. Individuals with psoriasis may suffer from depression and loss of self-esteem. Due to chronic recurrent nature Psoriasis is a challenge to treat. Ekakushtha (Psoriasis) is a kshudra kushtha, Vata-Kapha predominant disease, Aswedanam, Mahavastum, Matsya shakalopamam, Krishna Aruna Varna are the typical sign & symptoms described under Kushtha Rogas. The study is carried out as a comparative study of Vamana & Virechana. The study was done on 35 patients of Ekakushtha (Psoriasis), where 30 patients were completed divided into two groups. In group-A Vamana was given to the patients and after Sansarjana karma, shamana yoga & Jivantyadi yamaka was given for 28 days. Total 18 patients were registered in Group A out of which 3 were dropped out. In group-B Virechana was given to the patients and after Sansarjana karma, Shamana yoga & Jivantyadi yamaka have given for 28 days. Total 17 patients were registered in Group B, out of which 2 were dropped out.
High-Quality Thermal Oxide Grown on High-Temperature-Formed SiGe (2000)

We have developed a high‐quality gate oxide on with a 30 Å Si top layer. The good oxide integrity comparable to conventional thermal oxide is demonstrated by the low interface trap density of , low oxide charge of , small leakage current at 3.3 V of , high breakdown field of 13.8 MV/cm, good charge‐to‐breakdown of , and small stress‐induced leakage current. This good oxide integrity is directly related to our previously developed SiGe formed by solid phase epitaxy at high temperatures that is stable during thermal oxidation. This simple process is fully compatible with existing very large scale integration technology. © 2000 The Electrochemical Society. All rights reserved.
A Roundtable Discussion with Lawrence Lessig, David G. Post & Jeffrey Rosen (2001)

This article is a transcript of a discussion between Lawrence Lessig, David G. Post and Jeffrey Rosen on a variety of issues surrounding law, technology and the Internet. The moderator was Thomas E. Baker and the discussion was part of a Drake University Law School symposium in February of 2001.
Decline in sexually transmitted disease prevalence in female Bolivian sex workers (1998)

Effective prevention interventions for female CSW can be implemented through public services and non-governmental organizations while HIV rates are still low, and key outcomes can be monitored using data obtained from periodic screening examinations.
Weaving the Software Development Process Between Requirements and Architectures (2001)

This position paper argues for the concurrent, iterative development of requirements and architectures during the development of software systems. It presents the &quot;Twin Peaks&quot; model -- a partial and simplified version of the spiral model -- that illustrates the distinct, yet intertwined activities of requirements engineering and architectural design. The paper suggests that the use of various kinds of patterns -- of requirements, architectures, and designs -- may provide a way to increase software development productivity and stakeholder satisfaction in this setting.
Molecular sieving by a perforated Langmuir-Blodgett film (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular sieving by a perforated Langmuir-Blodgett filmMark Conner, Vaclav Janout, and Steven L. RegenCite this: J. Am. Chem. Soc. 1993, 115, 3, 1178–1180Publication Date (Print):February 1, 1993Publication History Published online1 May 2002Published inissue 1 February 1993https://pubs.acs.org/doi/10.1021/ja00056a070https://doi.org/10.1021/ja00056a070research-articleACS PublicationsRequest reuse permissionsArticle Views193Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design and development of an intelligent agent based framework for predictive analytics (2016)

The arrival of World Wide Web has led to the explosive growth of information on the web. There is a sudden boom in quality of raw data/information, which is commonly referred as Big Data. Very often, this raw information contains very useful insights which are ignored most of the time and are difficult to analyze due to the enormous size of these dataseis. The feasibility for human to extract this information from the vast web and build useful application on the top of it, is very low. Hence to create predictive models, there is a huge need for intelligent and autonomous software agents which can procure useful information from the large dataseis of raw information. Predictive analytics models can be created from these dataseis which can be further used for various applications in security, future prediction etc. This research paper gives an overview of how these software agents will become the most important tools in coming days for building predictive models.
Device-centric radio access virtualization for 5G networks (2014)

In this paper, we introduce a virtualized device-centric radio access architecture for future fifth-generation (5G) mobile networks. Radio access networks (RAN)s have traditionally relied on Voronoi tessellations of cells, created by a careful deployment of access nodes, to enable spatial frequency reuse over those cells. With the trend firmly set to decouple the control- and user-planes for next-generation 5G mobile networks, we foresee radio access technology breaking away from the concept of cells and embracing a virtualized device-centric architecture. The aim for this paradigm shift is to meet the stringent quality of service (QoS) requirements of densely populated networks irrespective of users' physical proximity to the access nodes. Focusing on downlink user-plane (U-plane) virtualization, this paper proposes a device-centric hyper-transceiver (HT) design that capitalizes on group-to-group (G2G) communications between virtual multipoint transmission and reception nodes and proactively optimizes both sets of virtual nodes via dynamic point selection (DPS) enabled by cloud-RAN (CRAN) architecture and semi-static network-assisted receiver cooperation enabled by device-to-device (D2D) short-range communications, respectively. Using a full-fledged event-based system level simulator compliant with the 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> generation partnership project (3GPP) long-term evolution advanced (LTE-Adv) specifications, our results show that the proposed virtualized U-plane architecture provides more than 50% average throughput and 200% coverage gains over LTE-A Release 11 baseline under some typical simulation scenarios.
Cyclic organophosphorus compounds. I. Synthesis and infrared spectral studies of cyclic hydrogen phosphites and thiophosphites (1967)

A general synthetic procedure leading to cyclic hydrogen phosphites has been devised. The effect of solvent on the P==O and P—H infrared stretching modes of cyclic hydrogen phosphites and thiophosphites has been studied. It is concluded that association of cyclic hydrogen phosphites is attributable to dipole–dipole interactions rather than to hydrogen bonding.
The Synthesis of Long Chain Substituted Isocyclics and Similarly Substituted Adipic Acids.<sup>1</sup> The Preparation of α-t-Octylcyclohexanone and a Method of Indirect Structure Proof for Ortho and Para Alkylphenols (1937)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of Long Chain Substituted Isocyclics and Similarly Substituted Adipic Acids.1 The Preparation of α-t-Octylcyclohexanone and a Method of Indirect Structure Proof for Ortho and Para AlkylphenolsJoseph B. Niederl and J. Bradley WhitmanCite this: J. Am. Chem. Soc. 1937, 59, 4, 717–718Publication Date (Print):April 1, 1937Publication History Published online1 May 2002Published inissue 1 April 1937https://pubs.acs.org/doi/10.1021/ja01283a034https://doi.org/10.1021/ja01283a034research-articleACS PublicationsRequest reuse permissionsArticle Views39Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Amorphous carbon (1986)

Abstract The properties of various types of amorphous carbon and hydrogenated amorphous carbon are reviewed with particular emphasis on the effect of atomic structure on the electronic structure. It is shown how the proportion of sp3 and sp2 sites not only defines the short-range order but also a substantial medium-range order. Medium-range order is particularly important in amorphous carbon because it is the source of its optical gap, whereas short-range order is usually sufficient to guarantee a gap in other amorphous semiconductors. The review discusses the following properties: short-range order and the radial distribution function, the infrared and Raman spectra, mechanical strength, the electronic structure, photoemission spectra, optical properties, electron energy-loss spectra, core-level excitation spectra, electrical conductivity, electronic defects and the electronic doping of hydrogenated amorphous carbon.
Characterization of the Propionyl-CoA Synthetase (PrpE) Enzyme of<i> Salmonella enterica</i>:  Residue Lys592 Is Required for Propionyl-AMP Synthesis (2002)

The propionyl-CoA synthetase (PrpE) enzyme of Salmonella enterica catalyzes the first step of propionate catabolism, i.e., the activation of propionate to propionyl-CoA. The PrpE enzyme was purified, and its kinetic properties were determined. Evidence is presented that the conversion of propionate to propionyl-CoA proceeds via a propionyl-AMP intermediate. Kinetic experiments demonstrated that propionate was the preferred acyl substrate (kcat/Km = 1644 mM(-1) x s(-1)). Adenosine 5'-propyl phosphate was a potent inhibitor of the enzyme, and inhibition kinetics identified a Bi Uni Uni Bi Ping Pong mechanism for the reaction catalyzed by the PrpE enzyme. Site-directed mutagenesis was used to change the primary sequence of the wild-type protein at positions G245A, P247A, K248A, K248E, G249A, K592A, and K592E. Mutant PrpE proteins were purified, and the effects of the mutations on enzyme activity were investigated. Both PrpEK592 mutant proteins (K592A and K592E) failed to convert propionate to propionyl-CoA, and plasmids containing these alleles of prpE failed to restore growth on propionate of S. enterica carrying null prpE alleles on their chromosome. Both PrpEK592 mutant proteins converted propionyl-AMP to propionyl-CoA, suggesting residue K592 played no discernible role in thioester bond formation. To the best of our knowledge, these mutant proteins are the first acyl-CoA synthetases reported that are defective in adenylation activity.
Anti—Ro/SS‐a Antibodies in the Pathophysiology of Congenital Heart Block in Neonatal Lupus Syndrome, An Experimental Model (1992)

Anti-Ro/SS-A antibodies may play a pathophysiologic role in the development of congenital heart block in neonatal lupus.
A spatial sensitivity analysis technique for neutron and gamma-ray measurements (1992)

In the fields of medical imaging, geophysical well logging, and industrial radiography, it is often of interest to characterize the spatially distributed sensitivities of neutron and gamma-ray measurement devices to the physical properties of the materials being examined. For instance, one may wish to know how the count rate in a detector varies in response to small changes in the local density of the irradiated object as a function of position. Experimental determination of such sensitivity functions is often impractical. Consequently, we have developed a general three-dimensional Monte Carlo numerical technique that allows us to directly compute the differential sensitivity of an arbitrary integral response parameter, such as a time- or energy-discriminated count rate, with respect to the spatial distribution of macroscopic cross sections and sources in the irradiated medium. Sensitivities to object density, porosity, etc., can easily be derived from these computed fundamental sensitivities. An efficient implementation of this algorithm has been achieved through modification of the widely used MCNP transport code. This work represents a generalization of the algorithm described, which was applied only to gamma-ray transport between 1 keV and 1 MeV. The present algorithm applies to neutron, gamma-ray, and coupled neutron-gamma transport problems under very generalmore » conditions. In the case of neutron devices, for instance, the code has been extensively utilized from 14 MeV to thermal energies. In this paper, we describe the theoretical basis of the numerical technique and discuss its application in nuclear geophysical well logging. Empirical support for the accuracy of the computed sensitivities is also discussed.« less
Transition‐Metal‐Free Multicomponent Reactions Involving Arynes, N‐Heterocycles, and Isatins (2013)

Mix and match: With isoquinoline as the nucleophilic trigger, multicomponent reactions afforded spirooxazino isoquinoline derivatives, proceeding through 1,4-dipolar intermediates. The use of pyridine as a nucleophile furnished indolin-2-one derivatives, with the reaction likely proceeding through a pyridylidene intermediate.
ChemInform Abstract: SYNTHESIS AND REACTIONS OF TETRAZOLO(1,5‐A)QUINOXALINES (1982)

Abstract Ausgehend von den Tetrazolochinoxalinen (Ia), (Ib) werden die Derivate (Ic) bis (If) dargestellt.
One story, one flow (2006)

This article presents a multidocument, multilingual, theme-based summarization system based on modeling text cohesion (story flow). Conventional extractive summarization systems which pick out salient sentences to include in a summary often disregard any flow or sequence that might exist between these sentences. We argue that such inherent text cohesion exists and is (1) specific to a particular story and (2) specific to a particular language. Documents within the same story, and in the same language, share a common story flow, and this flow differs across stories, and across languages. We propose using Hidden Markov Models (HMMs) as story models. An unsupervised segmental K-means method is used to iteratively cluster multiple documents into different topics (stories) and learn the parameters of parallel Hidden Markov Story Models (HMSM), one for each story. We compare story models within and across stories and within and across languages (English and Chinese). The experimental results support our “one story, one flow” and “one language, one flow” hypotheses. We also propose a Naïve Bayes classifier for document summarization. The performance of our summarizer is superior to conventional methods that do not incorporate text cohesion information. Our HMSM method also provides a simple way to compile a single metasummary for multiple documents from individual summaries via state labeled sentences.
Effects of molecular modification on hypocholesteremic activity of 1,3-bis(substituted phenoxy)-2-propanones and related derivatives (1978)

The crystallization behavior of isotactic polypropylene (iPP) in the vicinity of single-wall and multiwall carbon nanotubes (SWCNTs and MWCNTs) has been studied. Combined DSC and transmission electron microscopy (TEM) investigations of bulk composite materials reveal that CNTs nucleate iPP when crystallizing from the quiescent melt and that iPP crystals form a transcrystalline layer of aligned iPP lamellar crystals around the nucleating CNT. The pronounced nucleation effect and the formation of a transcrystalline layer is observed also for ultrathin film CNT/iPP samples. Corresponding diffraction studies show that in bulk as well as in the case of the ultrathin film samples only the ?-phase of iPP exists. The transcrystalline layer is highly oriented around the nucleating CNTs, and the crystallographic c-axes of the lamellae are oriented perpendicular to the long axis of the nucleating CNT, which is in contradiction to assumptions done in other studies. This crystallization behavior is discussed and a possible explanation is provided based on iPP macromolecules wrapped around rather than aligned along the CNTs prior to formation of the nucleus. © 2008 American Chemical Society