gebhart/patrepeval huggingface dataset:
A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine-induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel (2002)

Sudden death due to cardiac arrhythmia is a devastating event, especially when it occurs in children. In the absence of structural heart defects, five major arrhythmogenic disorders manifesting as polymorphic ventriculartachycardia (PVT) and/or ventricular fibrillation havebeen described: the long QT syndrome, right bundlebranch block and persistent ST elevations (Brugada syndrome), the "short coupled variant of torsade de pointes,"idiopathic ventricular fibrillation with normal electrocardiogram, and PVT induced by catecholamines (Viskinand Belhassen 1998). The last entity was initially described as a case report in 1975 (Reid et al. 1975) and asa distinct clinical entity in 1995 (Leenhardt et al. 1995).Catecholamine-induced PVT is a rare disease that occursin subjects without obvious organic heart disease, characterized by episodes of syncope, seizures, or sudden deathin response to physiological or emotional stress (Viskinand Belhassen 1998). Leenhardt et al. described 21 children (mean ± S.D. age, 9.9 ± 4 years) with no organic heartdisease and normal baseline ECG (except for sinus bradycardia), who suffered from episodes of syncope andseizures usually related to physiological or emotionalstress. The mean age at which the first syncope occurredwas 7.8 ± 4 years. They had no structural heart diseaseand a normal QT interval. In 30% of the patients therewas a family history of syncope or sudden death. Interestingly, the ventricular tachycardia (VT) could be reproduced in these patients either by a treadmill exercise testor by infusing small amounts of isoproterenol at a ratesufficient to accelerate the cardiac rate to 150–160 beatsper minute. Following treatment with beta-blockers, thepatients' symptoms underwent almost complete resolution, and no episodes of VT could be found on 24-hourholter monitoring. PVT affects mainly children, but infants (Shaw 1981) as well as adults (Eisenberg et al.1995) have also been reported as affected...
Propensity Score Analysis with Matching Weights (2011)

The propensity score analysis is one of the most widely used methods for studying the causal treatment effect in observational studies. This paper studies treatment effect estimation with the method of matching weights. This method resembles propensity score matching but offers a number of new features including efficient estimation, rigorous variance calculation, simple asymptotics, statistical tests of balance, clearly identified target population with optimal sampling property, and no need for choosing matching algorithm and caliper size. In addition, we propose the mirror histogram as a useful tool for graphically displaying balance. The method also shares some features of the inverse probability weighting methods, but the computation remains stable when the propensity scores approach 0 or 1. An augmented version of the matching weight estimator is developed that has the double robust property, i.e., the estimator is consistent if either the outcome model or the propensity score model is correct. In the numerical studies, the proposed methods demonstrated better performance than many widely used propensity score analysis methods such as stratification by quintiles, matching with propensity scores, and inverse probability weighting.
Degradation and Cupric Corrosion caused by Corrosive Sulfur in Insulating Oil (1995)

Refining method of insulating oil was changed from acid-refining to hydro-refining in the 1970's. And addtion of benzotriazole (BTA) in insulating oil was recognized in Japanese Industrial Standard in 1988. These changes are preferable to suppression of oxidative degradation and cupric corrosion phenomena caused by corrosive sulfur. We have studied oxidative degradation and cupric corrosion caused by corrosive sulfur. It is known that tanδ changes like N-character pattern in process of oxidative degradation. The maximum value of tanδ is proportional to amount of soluting copper, sulfur contents and inversely contents of aromatic compound in the insulating oil. The amount of corrosive sulfur in the insulating oil is at small level recently, but cupric corrosion caused by corrosive sulfur increases with amount of oxigen in the insulating oil. Cupric corrosion caused by corrosive sulfur is related to soluting copper and sulfuric ion in the insulating oil, therefore degree of cupric corrosion could be measured by soluting copper and sulfuric ion. We found that BTA is effective for both prevention of oxidative degradation and cupric corrosion caused by corrosive sulfur in the insulating oil.
Avaliação sensorial de sorvete formulado com produto de soro ácido de leite bovino (2006)

O soro de leite bovino é um subproduto da fabricação do queijo ou da caseína, existente na forma ácida ou doce. Constituído basicamente de água, proteínas, lactose e minerais, quando concentrado, implica na obtenção de vários ingredientes protéicos de alta funcionalidade e valor nutricional. Entretanto, a concentração do soro tem sido realizada apenas ao soro doce, sendo o soro ácido, devido às suas características, geralmente tratado como resíduo. Neste contexto, este artigo apresenta os resultados obtidos com a introdução de produto de soro ácido de leite na formulação de sorvete, em sistema modelo, verificando a percepção dos provadores para diferentes percentuais de substituição do leite desnatado. As amostras de sorvete foram preparadas com composição de mistura: 2,5% de gordura látea, 18,3% de sacarose, 2,3% de gema de ovo em pó e 0,3% de estabilizante-emulsificante e essência de baunilha. O sorvete padrão (P) foi formulado com 10,09% de leite desnatado em pó. Quatro outras misturas foram preparadas com o produto de soro ácido em pó (SAP), substituindo o leite desnatado, em níveis 100, 80, 60 e 30%. A avaliação do efeito provocado no sorvete, devido à substituição do leite desnatado por SAP, foi efetuada por ensaio sensorial direcionado à percepção do gosto doce. Não houve diferença estatisticamente significativa (p<0,5) entre as amostras quanto ao gosto doce avaliado. Houve boa aceitação dos provadores nos níveis de 60 e 30% em substituição.
Hepatic recognition and catabolism of serum glycoproteins. (1981)

WITH THE exception of albumin, essentially all serum proteins are glycoproteins, that is, proteins to which one or more carbohydrate chains are bound in covalent linkage. The sugars most commonly found in association with proteins are galactose, mannose,N-acetylhexosamine, sialic acid, and fucose. Glucose occurs rarely, if at all, as a normal constituent of circulating proteins. In general, the carbohydrate moiety may be envisaged as consisting of two domains. The outer, nonreducing terminus is composed of the trisaccharide, sialic acid-galactose-N-acetylglucosamine. Usually, between two and four such terminal triads may be linked glycosidically to the second domain, which is composed of three mannose and twoN-acetylglucosamine residues. The structure of a typical, complex carbohydrate chain is illustrated in the Figure. On treatment with neuraminidase, the sialic acid moiety is cleaved to reveal the penultimate galactose moiety as the new, nonreducing termini of the resulting asialoglycoprotein. Fucose, which
Analysis of an electronic voting system (2004)

With significant U.S. federal funds now available to replace outdated punch-card and mechanical voting systems, municipalities and states throughout the U.S. are adopting paperless electronic voting systems from a number of different vendors. We present a security analysis of the source code to one such machine used in a significant share of the market. Our analysis shows that this voting system is far below even the most minimal security standards applicable in other contexts. We identify several problems including unauthorized privilege escalation, incorrect use of cryptography, vulnerabilities to network threats, and poor software development processes. We show that voters, without any insider privileges, can cast unlimited votes without being detected by any mechanisms within the voting terminal software. Furthermore, we show that even the most serious of our outsider attacks could have been discovered and executed without access to the source code. In the face of such attacks, the usual worries about insider threats are not the only concerns; outsiders can do the damage. That said, we demonstrate that the insider threat is also quite considerable, showing that not only can an insider, such as a poll worker, modify the votes, but that insiders can also violate voter privacy and match votes with the voters who cast them. We conclude that this voting system is unsuitable for use in a general election. Any paperless electronic voting system might suffer similar flaws, despite any certification it could have otherwise received. We suggest that the best solutions are voting systems having a voter-verifiable audit trail, where a computerized voting system might print a paper ballot that can be read and verified by the voter.
An experimental study and model assessment of polymer sintering (1996)

Abstract Experiments were conducted using pairs of particles inside a hot stage microscopy setup with the ultimate objective to study the coalescence, which is a crucial stage in the rotational molding process. It was found that the geometry of the particles had no significant effect on the sintering rate. The sintering rate increases as the viscosity of the resin decreases. However, this effect became less important as the particle size decreased. The experimental results of this study have been compared with the available mathematical models based on balance of viscous and surface tension forces. The model developed by Frenkel and a corrected version by Eshelby predict a faster coalescence than observed experimentally. However, Hopper's model is in relatively good agreement with the present experimental data. Yet there is evidence that mechanisms other than Newtonian viscous flow may play a role in polymer sintering.
High efficiency boost DC/DC converter with skip mode (2008)

Based on the UMC 0.6 μm BCD process,a high efficiency peak-current-mode-controlled PWM boost DC/DC converter is presented in the paper.The skip mode is introduced to improve the efficiency when the converter works in the light load condition.The simulation result indicates that DC/DC converter which introduces skip mode presents over 45% efficiency in light load condition(load current less than 5mA).
A 1.8V to 10V CMOS level shifter for RFID transponders (2010)

A 1.8V-to-10V high-voltage tolerant level shifter (HVT level shifter) is presented in this paper. This new topology of HVT level shifter makes all the transistors working in safe operating region, and consequently greatly enhances the circuit's reliability. It has been fabricated in 0.18 µm CMOS process, and successfully integrated in an embedded EEPROM memory with 10 V programming/erasing voltages in the passive UHF RFID transponders.
ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentation (2019)

Semantic segmentation is a key problem for many computer vision tasks. While approaches based on convolutional neural networks constantly break new records on different benchmarks, generalizing well to diverse testing environments remains a major challenge. In numerous real-world applications, there is indeed a large gap between data distributions in train and test domains, which results in severe performance loss at run-time. In this work, we address the task of unsupervised domain adaptation in semantic segmentation with losses based on the entropy of the pixel-wise predictions. To this end, we propose two novel, complementary methods using (i) entropy loss and (ii) adversarial loss respectively. We demonstrate state-of-the-art performance in semantic segmentation on two challenging “synthetic-2-real” set-ups and show that the approach can also be used for detection.
<i>In silico</i>identification of putative metal binding motifs (2006)

Metal ion binding domains are found in proteins that mediate transport, buffering or detoxification of metal ions. In this study, we have performed an in silico analysis of metal binding proteins and have identified putative metal binding motifs for the ions of cadmium, cobalt, zinc, arsenic, mercury, magnesium, manganese, molybdenum and nickel. A pattern search against the UniProtKB/Swiss-Prot and UniProtKB/TrEMBL databases yielded true positives in each case showing the high-specificity of the motifs. Motifs were also validated against PDB structures and site directed mutagenesis studies.
<scp>d</scp>‐Allulose supplementation normalized the body weight and fat‐pad mass in diet‐induced obese mice via the regulation of lipid metabolism under isocaloric fed condition (2016)

Taken together, our findings suggest that 5% dietary d-allulose led to the normalization of the metabolic status of diet-induced obesity by altering lipid-regulating enzyme activities and their gene-expression level along with fecal lipids.
Prevention of lethal graft‐<i>vs</i>.‐host disease by a single low dose injection of anti‐T cell monoclonal antibody to the allograft recipients (1991)

We investigated the capacity of monoclonal antibody (mAb) treatment to prevent graft-vs.-host disease (GVHD) in lethally irradiated, allogeneically reconstituted mice, employing anti-T cell (subset) mAb and a fully allogeneic strain combination. In this strain combination, purified CD4+ cells were able to induce a lethal GVH reaction, whereas purified CD8+ cells were not. In the same strain combination, a single intraperitoneal injection of IgG2b anti-Thy-1 mAb, one day after reconstitution, caused a dose-dependent improvement of the survival. A single injection of a dose as low as 12.5 micrograms per mouse was already effective. Intravenous and intraperitoneal administration of the mAb appeared equally effective. For effective prevention of GVHD the treatment could be postponed until the 4th day after transplantation, but treatment delayed until day 6 was no longer effective. Treatment with IgG2b mAb specific for either helper or cytotoxic T cells also led to improvement of GVHD and survival, but was less effective than treatment with anti-Thy-1 mAb. Clinically, there was a difference in the effectiveness of anti-CD4 and anti-CD8 treatment, since symptoms of GVHD started earlier in the anti-CD8 treated group and the survival was better in the anti-CD4 treated group. These results press for prospective clinical studies employing anti-T cell mAb treatment early after allogeneic bone marrow transplantation, especially in HLA mismatched cases.
Reactions of the Chlorides of Phosphorus Acids with Unsaturated Compounds (1968)

The review deals with the reactions of the chlorides of acids derived from trivalent and tetravalent phosphorus with unsaturated compounds. Apart from their theoretical importance, these reactions are of great practical interest, since with their aid it is possible to obtain a wide variety of new and interesting types of organophosphorus compounds. In the first part of the review the addition reactions of various halides of trivalent phosphorus acids to ethylene and diene hydrocarbons, αβ-unsaturated aldehydes, ketones, and acids are considered, as well as the oxidative chlorophosphination of unsaturated compounds. The second part of the review is devoted to the reactions of the chlorides of pentavalent phosphorus acids with ethylenic, acetylenic, and diene hydrocarbons and with vinyl ethers and esters and also the addition reactions of dialkoxyphosphinothiolic and dialkoxyphosphinoselenolic chlorides.
A Frequency Offset Recovery Algorithm for Crystal-Less Transmitters (2006)

In the growing market of low-cost, low data-rate wireless applications there is a significant motivation to implement crystal-less wireless nodes, which will reduce costs and form factor. Several applications benefit from an asymmetric wireless scenario in which the transmitter is required to be cheap, small and ultra-low power, while the receiver will be a residential gateway (RG) or a basestation with a virtually unlimited power budget and relatively higher allowable cost and form factor. In this scenario, while the transmitter will be implemented as a crystal-less node, all the required complexity in the frequency synchronization can be shifted to the RG. Nevertheless the acquisition time should be short compared to the transmission time to save power in the transmitter, and frequency offset in the MHz range should be reduced to few kHz. A new algorithm, which can easily recover frequency offsets larger than the data-rate and which can address the aforementioned issues, is proposed in this paper.
Pedalvatar: An IMU-based real-time body motion capture system using foot rooted kinematic model (2014)

In this paper, we present a low-cost IMU-based system, Pedalvatar, which can capture the full-body motion of users in real-time. Unlike the prior approaches using the hip-joint as the root of forward kinematic model, a foot-rooted kinematic model is developed in this work. A state change mechanism has also been investigated to allow dynamically switching the root of kinematic trees between the left and the right foot. Benefitted from this, full-body motions can be well captured in our system as long as there is at least one static foot in the movement. The `floating' artifact of hip-joint rooted methods has been eliminated in our approach, and more complicated motions such as climbing stairs can be successfully captured in real-time. Comparing to those vision-based systems, this IMU-based system provides more flexibility on capturing outdoor motions that are important for many robotic applications.
Transport properties of pancreatic cancer describe gemcitabine delivery and response (2014)

Lustgarten Foundation (989161), Department of Defense (W81XWH-09-1-0212), NIH (U54CA151668, KCA088084).
On Baire class of Lyapunov exponents of linear differential equations: Dauylbaev A.M., Rakhimberdiev M.I. (2002)

It is proved that Lyapunov exponents of linear differential equations as functions of coefficient from the space of continious bounded functions belonging to second Baire class.
Resolution and linewidth tolerances in electron beam and optical projection lithography (1981)

In order to understand the practical limits of electron beam direct-write and optical projection lithography techniques in device fabrication with micrometer and submicrometer geometries, we have exercised two computer simulation programs to estimate resolution limits and linewidth control. Latent image contrast and developed resist thickness contrast were calculated as a function of line-array spatial frequency. The linewidth tolerances were calculated by varying exposure, development time, focusing, line/space Pattern, resist thickness, etc. These simulation results indicate that the lithographic performance of the two techniques using state-of-the-art exposure tools are comparable at 1-µm dimensions. Some relevant experimental data also are presented.
Image Processing by Compression: An Overview (2012)

This article aims to present the various applications of data compression in image processing. Since some time ago, several research groups have been developing methods based on different data compression techniques to classify, segment, filter and detect digital images fakery. It is necessary to analyze the relationship between different methods and put them into a framework to better understand and better exploit the possibilities that compression provides us respect to image processing; compression becomes very easy techniques to apply without much technical requirement. In this article we will also see the types of compression and specific image compressors.1
Cricoid pressure: indications and complications (2004)

Cricoid pressure to occlude the upper end of the oesophagus, also called the Sellick manoeuvre, may be used to decrease the risk of pulmonary aspiration of gastric contents during intubation for rapid induction of anaesthesia. Effective and safe use of the technique requires training and experience. Cricoid pressure is contraindicated in patients with suspected cricotracheal injury, active vomiting, or unstable cervical spine injuries. The technique may be particularly difficult in patients with a history of difficult intubation. The recommended pressure to prevent gastric reflux is between 30 and 40 Newtons (N, equivalent to 3-4 kg), but pressures greater than 20 N cause pain and retching in awake patients and a pressure of 40 N can distort the larynx and complicate intubation. The recommended procedure is, therefore, to induce anaesthesia and apply a pressure of about 30 N, either manually or with the cricoid yoke, to facilitate intubation. Reported complications of cricoid pressure during intubation include oesophageal rupture and exacerbation of unsuspected airway injuries.
Phenotypic variation and diversity among Trichomonas vaginalis isolates and correlation of phenotype with trichomonal virulence determinants (1986)

The extent and nature of heterogeneity among representative Trichomonas vaginalis isolates were evaluated by flow cytofluorometry analysis. Monoclonal antibody and monospecific antiserum to an immunodominant trichomonad surface glycoprotein with a molecular weight of 267,000 (267K glycoprotein) were used to evaluate fresh isolates (JHH and RU375) and long-term grown isolates (NYH286, IR78, and JH31A) of T. vaginalis. Isolates NYH286, JH31A, and JHH were made up of heterogeneous staining (positive [pos] phenotype) and nonstaining (negative [neg] phenotype) populations of trichomonads, whereas RU375 and IR78 were all neg phenotype parasites. Flow cytofluorometric patterns of agar clones derived from single organisms of heterogeneous isolates such as NYH286 showed populations which were either homogeneous pos or neg and also showed clones which were heterogeneous in nature containing both phenotypes. Fluorescence-activated cell sorting was also accomplished, and subpopulations of defined pos or neg phenotype were purified. Flow cytofluorometry evaluation of all isolates for an extended period revealed a phenotypic variation among all heterogeneous isolates and also for all clones and subpopulations derived from the heterogeneous isolates. On the other hand, IR78 and RU375 did not undergo phenotypic variation and have remained neg for greater than 4 years. Parasites which were nonreactive with either monoclonal antibody or monospecific antiserum to the 267K glycoprotein in flow cytofluorometry did not possess the antigen on their surface. This was determined by radioimmunoprecipitation assays using extracts of iodinated trichomonads. Finally, neg phenotype parasites yielded enhanced rates of contact-dependent cytotoxicity of host cell monolayers as compared with the pos phenotype trichomonads.