gebhart/patrepeval huggingface dataset:
Efficacy of AT in pre-eclampsia: a case-control prospective trial (2003)

Pre-eclampsia is an extremely severe condition. It is associated with vasospasm, activation of the coagulation system and abnormal haemostasis. In pre-eclamptic patients increased plasmatic concentrations of fibronectin, laminin, von Willebrand factor (VWF) and endothelin are observed. Experimental studies on rats have also shown that the doses of antithrombin III (AT) needed to mediate anti-inflammatory processes are much higher than those required to obtain the anti-coagulant effect. The study aimed to evaluate the clinical efficacy of treatment with high AT doses (HD) in comparison with standard doses (SD). The primary endpoint was the prolongation of pregnancy defined as time (in days) from enrollment to delivery and to assess the maternal bleeding at and after delivery. The secondary endpoint was to demonstrate a role for AT in controlling haemostasis at conventional doses, and the inflammatory state at higher doses. The biochemical parameters assessed were: AT activity (%), Fibronectin (Fn), Fibrinogen, D-dimer, Uricemia, Proteinuria 24h, Protein C Reactive (PCR), Granulocyte Elastase and Endothelin. This study included 23 pre-eclamptic women. Patients were randomly subdivided into two groups: 10 patients ("cases") were treated with high doses of AT (6 vials: 3000 units) once daily for 5 days, or until delivery, while 13 women ("controls") were treated with doses of AT sufficient to maintain at least 80% of the activity. High-dose therapy was associated with prolongation of pregnancy by 2.5 days more when compared with controls (p = 0.03; Mann-Whitney test). The incidence of clinical significant bleeding was lower in cases than in controls (mean 550 mL vs. 650 mL, respectively). Preventive- and conservative-type treatment of moderate-severe pre-eclampsia, based on the administration high doses of AT, allows a significant prolongation of pregnancy, and thus a better neonatal outcome, as well as less maternal intra- and post-operative bleeding. Fn, PCR and elastase levels (markers of inflammation) decrease in the HD group in comparison with SD group. In the HD group, the AT plasma levels were obviously higher both at the end of the treatment (p < 0.0001) and after delivery (p = 0.03), in comparison with SD group. The fibrinogen and D-dimer levels were above the reference interval in both groups. TPA and PAI 1 were found to be significantly raised in the course of pre-eclampsia. In conclusion, the bio-chemical findings support a role for AT in controlling the haemostasis at conventional doses, and the inflammatory state at higher doses.
Effect of Surface Nano Crystallization on Tribological Properties of Stainless Steel (2006)

A novel surface treatment has been developed in the present work to enhance the tribological properties of 316L Stainless Steel. This Technique involves the formation of a nanocrystalline layer ascribable to a grain refinement mechanism induced by repeated impact loadings supported by the surface. The resultant system has a layered structure, comprising nanometric grains (less than 100 nm) at the top and a strain hardened transition layer in the subsurface. Such a microstructural feature has the potential to significantlty enhance the surface hardness and to create a high compressive residual stress state. The tribological properties of the stainless steel are thus improved in terms of lower friction coefficient and increased wear resistance. Detailed studies on the response of the nanocrystalline surface layer to annealing at temperatures between 400°C and 600°C showed that an annealing at high temperature can offer much better tribological enhancement than low temperature annealings due to enhanced martensitic transformation.
Tumor detection in ultrasound B-mode images through motion estimation using a texture detection algorithm (2002)

A method is described for the determination of an immobile region of an ultrasound image of the heart. Following a noise reduction operation using an optimal signal-adaptive algorithm, a luminance-based block matching technique is used to determine the motion field. Subsequently, the motion field map as processed and the immobile region is extracted by using a 2-D texture separating algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Exploiting Instruct Recognized Scheme to Improve Processor Performance (2004)

The authors introduce a new data prefetching technology that includes two schemes: instruction recognizing (IRing) and the dataprefetch buffering (DPB). The IRing is achieved by the instruction register, comparer, and the previous table. The DP R is implemented to the data reuse register and the data prefetching register. The authors build this new data prefetcher for reducing the accessed latency time of needed data and for improving the processor performance. The evaluation results in terms of the throughput show that the proposed data prefetcher is on average more effective than the pipeline processor. For this proposed data-prefetching scheme, the throughput improvement is 1.32 times the pipeline processor one’s.
Preparation of quinol N-acyl- and quinol ether imines via anodic oxidation of para-substituted anilide derivatives (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of quinol N-acyl- and quinol ether imines via anodic oxidation of para-substituted anilide derivativesJohn S. Swenton, Timothy N. Biggs, and William M. ClarkCite this: J. Org. Chem. 1993, 58, 21, 5607–5614Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/jo00073a016https://doi.org/10.1021/jo00073a016research-articleACS PublicationsRequest reuse permissionsArticle Views206Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
An instance of the application download pattern (1997)

Article Free Access Share on An instance of the application download pattern: the SPAIDS software loader/verifier domain analysis and implementation Authors: John D. Riley DCS Corporation, 1330 Braddock Place, Alexandria, Virginia DCS Corporation, 1330 Braddock Place, Alexandria, VirginiaView Profile , Sangiv Dungari U.S. Army Tank-Automotive RD&E Center (TARDEC), Warren, MI U.S. Army Tank-Automotive RD&E Center (TARDEC), Warren, MIView Profile , William Pritchett DCS Corporation, 1330 Braddock Place, Alexandria, Virginia DCS Corporation, 1330 Braddock Place, Alexandria, VirginiaView Profile Authors Info & Claims TRI-Ada '97: Proceedings of the conference on TRI-Ada '97November 1997 Pages 273–278https://doi.org/10.1145/269629.269656Online:01 November 1997Publication History 0citation218DownloadsMetricsTotal Citations0Total Downloads218Last 12 Months3Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Key Role for Endogenous Gibberellins in the Control of Seed Germination (1989)

The stimulative action of applied gibberellins (GA) on seed germination has been reported for a large number of species in the past three decades. Applied GA often replaces the need for environmental stimuli like specific temperature pretreatment or light. Therefore, it has been suggested that endogenous GAs are essential intermediates in the stimulation of germination. Endogenous GAs have been identified in seeds of a limited number of species, but most of the evidence for a regulatory role is entirely circumstantial. The use of isogenic mutants with lesions in the GA biosynthesis has presented direct evidence of a key role for endogenous GAs in the regulation of germination. GA deficiency absolutely prevents germination in seeds of Arabidopsis thaliana and tomato. Two different mechanisms of action exist The first one involves hydrolysis of reserve food. In seeds of tomato a factor, probably GA, diffuses prior to germination from embryo to endosperm where it induces hydrolysis of gaJactomannan-rich cell walls that are part of the mechanical resistance to the protrusion of the radicle. A second mechanism of GA action consists of a direct effect on the growth potential of the embryo. In Arabidopsis the stimulation of germination by light depends on the ability of the seeds to synthesize GA, but light also enhances the sensitivity of the seeds to GA. Dry storage and pre-incubation at 2°C also increased the responsiveness of Arabidopsis seeds to GA
Complex Affect Recognition in the Wild (2017)

Artificial social intelligence is a step towards human-like human-computer interaction. One important milestone towards building socially intelligent systems is enabling computers with the ability to process and interpret the social signals of humans in the real world. Social signals include a wide range of emotional responses from a simple smile to expressions of complex affects. This dissertation revolves around computational models for social signal processing in the wild, using multimodal signals with an emphasis on the visual modality. We primarily focus on complex affect recognition with a strong interest in curiosity. In this dissertation,we ?rst present our collected dataset, EmoReact. We provide detailed multimodal behavior analysis across audio-visual signals and present unimodal and multimodal classi?cation models for affect recognition. Second, we present a deep multimodal fusion algorithm to fuse information from visual, acoustic and verbal channels to achieve a uni?ed classi?cation result. Third, we present a novel system to synthesize, recognize and localize facial occlusions. The proposed framework is based on a three-stage process: 1) Synthesis of naturalistic occluded faces, which include hand over face occlusions as well as other common occlusions such as hair bangs, scarf, hat, etc. 2) Recognition of occluded faces and differentiating between hand over face and other types of facial occlusions. 3) Localization of facial occlusions and identifying the occluded facial regions. Region of facial occlusion, plays an important role in recognizing affect and a shift in location can result in a very different interpretation, e.g., hand over chin can indicate contemplation, while hand over eyes may show frustration or sadness. Finally, we show the importance of considering facial occlusion type and region in affect recognition through achieving promising results in our experiments.
Pose estimation problem in computer vision (2002)

Pose estimation is an important topic in the field of computer vision, which may find a lot of applications in practice and various algorithms in the literature. This paper gives a comprehensive treatment of the so-called Perspective-N-Point (PNP) problem.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The new book of saddlery and tack (1998)

Serious horsemen as well as collectors and dealers will appreciate this visually opulent survey of bits, saddles, bridles, harnesses, and all the related horse gear imaginable. This authoritative reference ranges in coverage from the simple devices of Classical times to state-of-the-art equipment advertised in the latest tack catalog. Each chapter is written by an acknowledged expert on the subject, and the entire editorial and pictorial context of The New Book of Saddlery and Tack has been supervised by Carolyn Henderson, a well-known authority on equestrian matters.
THIS ARTICLE HAS BEEN RETRACTED: Toll‐like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury (2008)

Toll-like receptors (TLRs) play an essential role in innate immune responses and in the initiation of adaptive immune responses. Microglia, the resident innate immune cells in the CNS, express TLRs. In this study, we show that TLR3 is crucial for spinal cord glial activation and tactile allodynia after peripheral nerve injury. Intrathecal administration of TLR3 antisense oligodeoxynucleotide suppressed nerve injury-induced tactile allodynia, and decreased the phosphorylation of p38 mitogen-activated protein kinase, but not extracellular signal-regulated protein kinases 1/2, in spinal glial cells. Antisense knockdown of TLR3 also attenuated the activation of spinal microglia, but not astrocytes, caused by nerve injury. Furthermore, down-regulation of TLR3 inhibited nerve injury-induced up-regulation of spinal pro-inflammatory cytokines, such as interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha. Conversely, intrathecal injection of the TLR3 agonist polyinosine-polycytidylic acid induced behavioral, morphological, and biochemical changes similar to those observed after nerve injury. Indeed, TLR3-deficient mice did not develop tactile allodynia after nerve injury or polyinosine-polycytidylic acid injection. Our results indicate that TLR3 has a substantial role in the activation of spinal glial cells and the development of tactile allodynia after nerve injury. Thus, blocking TLR3 in the spinal glial cells might provide a fruitful strategy for treating neuropathic pain.
A simple and new optimum combining scheme for CDMA down link signals (2004)

This paper presents a new optimum combining scheme for a CDMA wireless mobile receiver. The new combining scheme, compared to conventional maximal ratio combining (MRC), not only combats multi-path fading, but also mitigates interference by further scaling the finger output inversely proportional to its total average interference power. This interference power is found to be mutually uncorrelated among fingers and its average power is proportional to its instantaneous gain. The reason being that the interference power varies at the chip rate (MHz) while channel gain varies at the fading rate (hundreds of Hz). It is also found that the interference caused by non-orthogonality due to multi-path delays is same for all the fingers. This makes the optimum weights depend only on the channel impulse response and renders an easy way to obtain the optimum weights without actually measuring or estimating the interference power. In this paper, we show how the proportional scaling finger outputs can be performed based on a finger's own instantaneous channel gain. Therefore the new combining RAKE receiver is simply an MRC RAKE receiver with each finger's weight further scaled proportionally to the instantaneous channel gain. Compared with other optimum combining schemes, such as DMI or LMS the new scheme has much lower cost, does not have sample support problems and converges to MRC when there is no interference or the multi-paths have equal average power. Simulation results show that the proposed optimum combining RAKE receiver has a 0.3 dB to 2.5 dB gain over the MRC RAKE receiver.
Biotransformation of the Naturally Occurring Isothiocyanate Sulforaphane in the Rat:  Identification of Phase I Metabolites and Glutathione Conjugates (1997)

Sulforaphane (SFN) is a naturally occurring isothiocyanate present in cruciferous vegetables, such as broccoli, that has been identified as a potent inducer of glutathione S-transferase activities in laboratory animals. The present studies were carried out to elucidate the metabolic fate of SFN in the rat. Particular emphasis was placed on glutathione (GSH)-dependent pathways because conjugation with GSH is a major route by which many isothiocyanates are eliminated in mammals. Male Sprague-Dawley rats were administered a single dose of SFN (50 mg kg-1 ip), and bile and urine were collected over ascorbic acid. Analysis of biological fluids was carried out by ionspray LC-MS/MS using the neutral loss (129 Da) and precursor ion (m/z 164) scan modes to detect GSH and N-acetylcysteine (NAC) conjugates, respectively. In bile, five thiol conjugates (designated M1-M5) were detected. Metabolites M2 and M4 were identified as the GSH conjugates of SFN and erucin (ERN, the sulfide analog of SFN), respectively, by comparing their LC-MS/MS properties with those of standards obtained by synthesis. M1 was characterized as the GSH conjugate of a desaturated metabolite of SFN (tentatively assigned the structure of delta 1-SFN), suggesting that the parent compound also undergoes oxidative metabolism. Metabolites M3 and M5 were identified as the NAC conjugates of SFN and ERN, respectively, and together with the NAC conjugate of delta 1-SFN, these species also were detected in urine. Quantitative determination of the former two mercapturates in urine indicated that approximately 60% and approximately 12% of a single dose of SFN is eliminated in 24 h as the NAC conjugates of SFN and ERN, respectively. The corresponding figures in rats dosed with ERN were approximately 67% and approximately 29%. When the GSH conjugate of SFN was incubated with phosphate buffer (pH 7.4, 37 degrees C), < 1% of the conjugate dissociated to liberate free SFN. On the other hand, the conjugate underwent a facile thiol exchange reaction (> 70% conversion) when incubated in the presence of excess cysteine, thereby acting as an effective carbamoylating agent. It is concluded that SFN undergoes metabolism by S-oxide reduction and dehydrogenation and that GSH conjugation is the major pathway by which the parent compound and its phase I metabolites are eliminated in the rat.
Breast tumors: comparative accuracy of MR imaging relative to mammography and US for demonstrating extent. (1995)

MR imaging was the most accurate of the three preoperative imaging modalities in assessing the size and number of malignant lesions in the breast.
Compensation of the Birefringence of a Polymer by a Birefringent Crystal (2003)

We report a method for compensating the birefringence of optical polymers by doping them with inorganic birefringent crystals. In this method, an inorganic birefringent material is chosen that has the opposite birefringence to that of the polymer and has rod-shaped crystals that are oriented when the polymer chains are oriented. The birefringence of the polymer is thus compensated by the opposing birefringence of the crystal. Birefringence is minimized in various polymer optical devices by adjusting process conditions, because it degrades the performance of devices. This method minimizes it, independent of process conditions, which potentially improves the productivity of devices.
SOI circuits powered by embedded solar cell (2011)

Solar cells embedded in the SOI substrate were successfully used as the sole energy source to power a ring oscillator fabricated using an ultra-low-power fully depleted SOI process on the same wafer. The speed of the ring oscillator increased with increasing light intensity and showed a fastest oscillation with a 4.5 ns stage delay and 0.26 fJ power-delay product. The maximum power generated by the solar cell was 9.6 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> with an efficiency of 11.6%.
Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in <i>CCNE1</i> -Amplified Ovarian Cancer (2013)

These findings suggest that cyclinE1/CDK2 is an important therapeutic target in HGSC, but that resistance to CDK2 inhibitors may emerge due to upregulation of CDK2 target protein and through preexisting cellular polyploidy.
Epitaxial growth of lead zirconium titanate thin films on Ag buffered Si substrates using rf sputtering (2007)

Epitaxial lead zirconium titanate (PZT) (001) thin films with a Pt bottom electrode were deposited by rf sputtering onto Si(001) single crystal substrates with a Ag buffer layer. Both PZT(20∕80) and PZT(53∕47) samples were shown to consist of a single perovskite phase and to have the (001) orientation. The orientation relationship was determined to be PZT(001)[110]‖Pt(001)[110]‖Ag(001)[110]‖Si(001)[110]. The microstructure of the multilayer was studied using transmission electron microscopy (TEM). The electron diffraction pattern confirmed the epitaxial relationship between each layer. The measured remanent polarization Pr and coercive field Ec of the PZT(20∕80) thin film were 26μC∕cm2 and 110kV∕cm, respectively. For PZT(53∕47), Pr was 10μC∕cm2 and Ec was 80kV∕cm.
Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation (2013)

Under resting physiological conditions CB1-receptor mediated mechanisms appear to have limited influence on systemic or cerebral circulation. Enhancement of endocannabinoid levels, however, induces transient CB1-independent hypertension and sustained CB1-mediated hypotension. Furthermore, enhanced endocannabinoid activity results in respiratory depression in a CB1-dependent manner. Finally, our data indicate for the first time the involvement of the endocannabinoid system and CB1-receptors in the regulation of the cerebral circulation during H/H and also raise the possibility of their contribution to the autoregulation of CoBF.
Defined crystallization of amorphous-silicon films using contact printing (2000)

Patterned Ni layers are printed on amorphous-silicon (a-Si) films and, during this printing, the metal patterns induce lateral crystallization of the precursor a-Si layer. The printing process consists of simultaneously pressing the Ni printing plate to an a-Si layer and annealing at 550 °C. Printing times of 1 and 3 h are explored. The growth rate of the Ni-induced lateral crystallization is about 8 μm/h in this process. After this printing, Raman spectra show that the resulting polycrystalline-silicon (poly-Si) regions have the characteristic transverse-optical 519 cm−1 phonon peak typical of crystalline silicon. The nonprinted, noncrystallized a-Si areas have the Raman signature of a-Si; i.e., they do not have any peak. The resulting laterally crystallized Si area shows a morphological texture (i.e., a strip-like morphology) originating from the printed Ni area and growing in one direction in transmission electron microscope imaging. In terms of the selective area diffraction pattern (i.e., diffraction spot position and crystal structure), the signature of the area directly contacted by the Ni cannot be distinguished from that of the surrounding laterally crystallized silicon film. This printing approach can be used for channel crystallization/device isolation resulting in a saving of device fabrication steps.