gebhart/patrepeval huggingface dataset:
5 V Class All-Solid-State Composite Lithium Battery with Li[sub 3]PO[sub 4] Coated LiNi[sub 0.5]Mn[sub 1.5]O[sub 4] (2003)

A 5 V class ceramic/polymer composite all-solid-state lithium battery was prepared. The cell configuration was coated |solid polymer electrolyte| Li]. The total cell impedance was 4 kΩ at 333 K and the discharge capacity was with a discharge voltage plateau in both 4.7 and 4.1 V regions. X-ray absorption near-edge structure results indicated that both transition metal ions, Ni and Mn, involved in the oxidation/reduction processes. The cell without showed a lower discharge voltage plateau (<3.5 V) than the composite one. Although the film was so thin that it could be nearly removed with only 2 min of Ar etching in X-ray photoelectron spectroscopy, is thought to have a function as a solid electrolyte interface between and SPE to prevent the degradation of solid polymer electrolyte. © 2003 The Electrochemical Society. All rights reserved.
Coronary Artery Bypass with the Use of a Magnetic Distal Anastomotic Device: Surgical Technique and Preliminary Experience (2004)

The MVP system is a novel distal coronary anastomotic device that is quick, simple, and effective, producing consistently reliable coronary anastomoses in a wide variety of coronary bypass procedures. Early results are encouraging, and further studies are required in order to evaluate long-term efficacy of this system in the rapidly changing world of coronary revascularization.
The Growing Burden of Diabetes Mellitus in the US Elderly Population (2008)

The burden of financing and providing medical care for persons older than 65 in the United States having diagnosed diabetes is growing rapidly as a result of increased incidence and, especially, prevalence of diagnosed diabetes, decreased mortality, and overall lack of improvement in rates of complications in persons having diagnosed diabetes.
Rigorous analysis of crosspolarisation in flange-mounted rectangular-waveguide radiators (1977)

A rigorous Nh-order Rayleigh-Ritz variational solution to the problem of a flange-mounted rectangular waveguide radiating into a halfspace is formulated. The analysis shows the importance of including higher-order modes whose electric fields are polarised orthogonally to the dominant mode. The mechanism of coupling from the dominant mode to the higher-order modes is discussed and numerical results for the aperture admittance are given.
Efficient Dense Reconstruction from Video. (2011)

We present a framework for efficient reconstruction of dense scene structure from video. Sequential structure-from-motion recovers camera information from video, providing only sparse 3D points. We build a dense 3D point cloud by performing full-frame tracking and depth estimation across sequences. First, we present a novel algorithm for sequential frame selection to extract a set of key frames with sufficient parallax for accurate depth reconstruction. Second, we introduce a technique for efficient reconstruction using dense tracking with geometrically correct optimisation of depth and orientation. Key frame selection is also performed in optimisation to provide accurate depth reconstruction for different scene elements. We test our work on benchmark footage and scenes containing local non-rigid motion, foreground clutter and occlusions to show comparable performance to state of the art techniques. We also show a substantial increase in speed on real world footage compared to existing methods, when they succeed, and successful reconstructions when they fail.
New nucleoside analogues and their 5′-triphosphates: Synthesis and biological properties (2008)

Bicyclic furano-and pyrrolo[2,3-d]pyrimidine nucleosides and purine nucleosides modified at the N1 atom and/or the 6-position have been synthesized. Among the tested nontoxic bicyclic nucleosides and N6-carboxyalkyladenosines, only furo[2,3-d]pyrimidine with the C10H21 substituent and N6-carboxymethyladenosine exhibit moderate anti-HCV activity in the virus replicon system and N1-hydroxyinosine exhibits high anti-HCV activity and significant cytotoxicity. The corresponding 5′-triphosphates have been synthesized and studied as substrates/inhibitors of HCV enzymes: NS5B protein (RNA-dependent RNA polymerase) and NS3 protein (NTP-dependent RNA helicase).
Rapid Preparation of Functional Murine Peyer's Patch Cells (1990)

The preparation of cells of Peyer's patches (PP) from mice and some immunological activities of the cells were examined. The PP cells were obtained with high yield (>1×107/CDF1 mouse) and viability (>97%), when the PP were cut and teased gently with two glasses in RPMI 1640 medium containing 5% heat-inactivated calf serum. The PP cells responded well to mitogens, and particularly the responses to a T cell mitogen, concanavalin A (Con A), were at similar levels to those of spleen cells. When the cells were stimulated with alloantigens in mixed lymphocyte reaction, significant response was observed. The PP cells cultured with lipopolysaccharide (LPS) exhibited polyclonal B cell responses (antigen-nonspecific increase in the number of antibody-producing cells). Furthermore, the levels of anti sheep erythrocytes (SRBC) plaque-forming cells (PFC) in PP cell cultures increased significantly when the PP cells were cultured with SRBC in vitro. However, the PP cells did not show the natural killer (NK) activity. These results showed that the PP cells obtained by the physical method described here contained functionable T and B lymphocytes and accessory cells.
Dopamine correlates of neurological and psychological status in untreated Parkinsonism (1976)

Thirty-seven untreated Parkinsonism patients showed significant positive correlations among decreased excretion of free dopamine, MMPI scores indicative of schizophrenic-like looseness of thinking, and the severity of all Parkinsonism signs except tremor. The data could indicate that abnormalities of dopamine metabolism may underlie both the motor and mental abnormalities of Parkinsonism.
A new concept for the lateral DMOS transistor for smart power IC's (2003)

In this paper, a new concept of lateral DMOSFET for smart power integrated circuits is proposed, in which a vertical trench is used under the gate end in the drift region.
Role of the Polyadenylate Segment in the Translation of Globin Messenger RNA in <i>Xenopus</i> Oocytes (1974)

The translations of native messenger RNA for rabbit globin and that of poly(A)-free globin messenger RNA have been compared after injection into Xenopus oocytes. The initial rate of translation of poly(A)-free mRNA is close to that found with intact mRNA. However, at longer incubation periods, the rate of globin synthesis with poly(A)-free mRNA is considerably lower than with native mRNA. Similar differences in the template activity of the two mRNA preparations were found with a cell-free extract of Krebs II ascites tumor. It is concluded that the presence of the 3' poly(A)-rich sequence in mRNA is required to ensure high functional stability.
Synthesis and stereochemistry of Reissert compounds from benzothiazole (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and stereochemistry of Reissert compounds from benzothiazoleAshish Pandya and Harry W. GibsonCite this: J. Org. Chem. 1993, 58, 10, 2851–2855Publication Date (Print):May 1, 1993Publication History Published online1 May 2002Published inissue 1 May 1993https://doi.org/10.1021/jo00062a032Request reuse permissionsArticle Views179Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (629 KB) Get e-Alertsclose Get e-Alerts
Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: Initial monotherapy outcomes at 12 months (2012)

As initial monotherapy, the superior effectiveness of ethosuximide and valproic acid compared to lamotrigine in controlling seizures without intolerable adverse events noted at 16-20 weeks persisted at 12 months. The valproic acid cohort experienced a higher rate of adverse events leading to drug discontinuation as well as significant negative effects on attentional measures that were not seen in the ethosuximide cohort. These 12-month outcome data coupled with the study's prespecified decision-making algorithm indicate that ethosuximide is the optimal initial empirical monotherapy for CAE. This is the first randomized controlled trial meeting International League Against Epilepsy (ILAE) criteria for class I evidence for CAE (or for any type of generalized seizure in adults or children). (NCT00088452.).
Autoinducer 2 Affects Biofilm Formation by<i>Bacillus cereus</i> (2006)

Cell-free supernatants from growing Bacillus cereus strain ATCC 10987 induced luminescence in a Photorhabdus luminescens DeltaluxS mutant, indicating the production of functional autoinducer 2 (AI-2). The exogenous addition of in vitro synthesized AI-2 had an inhibitory effect on biofilm formation by B. cereus and promoted release of the cells from a preformed biofilm.
Ck Continuity of Subdivision Surfaces (1996)

Stationary subdivision is an important tool for generating smooth free-form surfaces for CAGD and computer graphics. One of the challenges in construction of subdivision schemes for arbitrary meshes is to guarantee that the limit surface will have smooth regular parameterization in a neighborhood of any point. First results in this direction were obtained only recently. In this paper we derive necessary and sufficient criteria for Ck -continuity that generalize and extend most known conditions. We create a general mathematical framework that can be used for analysis of more general types of schemes. Finally, we prove a degree estimate for Ck -continuous polynomial schemes generalizing an estimate of Reif [20] and give a practical sufficient condition for smoothness.
Models overestimate diffuse clear‐sky surface irradiance: A case for excess atmospheric absorption (1998)

Radiative transfer models consistently overestimate surface diffuse downward irradiance in cloud‐free atmospheres by 9 to 40% at two low altitude sites while correctly calculating direct‐normal Solar irradiance. For known systematic and random measurement errors and for realistic aerosol optical properties, the discrepancy can be resolved by a reduction in the vertical aerosol optical thickness (AOT) inferred from sunphotometric measurements by an average 0.02 ± 0.01 for 32 cases examined, together with a compensating increase in a continuum‐like atmospheric absorptance over the solar spectrum of ∼5.0% ± 3.0%. This phenomenon is absent at two high altitude sites, where models and measurements agree to within their mutual uncertainties. Examination of apparent AOT at several locations around the globe also indicates presence of such excess atmospheric absorption. The proposed absorption and corresponding reduction in AOT would have important consequences for climate prediction and remote sensing.
Synthesis, characterization and biological evaluation of mixed-ligand ruthenium(<scp>ii</scp>) complexes for photodynamic therapy (2015)

We demonstrated the photodynamic therapy effect of mixed-ligand Ru(<sc>ii</sc>) complexes.<bold>Ru1–Ru3</bold>can kill cancer cells effectively upon light exposure through generating singlet oxygen and hydroxyl radical ions.
Biodiversity and Classification of Lactococcal Phages (2006)

For this study, an in-depth review of the classification of Lactococcus lactis phages was performed. Reference phages as well as unclassified phages from international collections were analyzed by stringent DNA-DNA hybridization studies, electron microscopy observations, and sequence analyses. A new classification scheme for lactococcal phages is proposed that reduces the current 12 groups to 8. However, two new phages (Q54 and 1706), which are unrelated to known lactococcal phages, may belong to new emerging groups. The multiplex PCR method currently used for the rapid identification of phages from the three main lactococcal groups (936, c2, and P335) was improved and tested against the other groups, none of which gave a PCR product, confirming the specificity of this detection tool. However, this method does not detect all members of the highly diverse P335 group. The lactococcal phages characterized here were deposited in the Félix d'Hérelle Reference Center for Bacterial Viruses and represent a highly diverse viral community from the dairy environment.
Hearing Aid Gain for Loudness-Density Normalization in Cochlear Hearing Losses with Impaired Frequency Resolution (1991)

A theoretical criterion for preliminary prescription of hearing aid gain and frequency response was formulated on the basis of Zwicker's loudness model, modified for impaired auditory frequency resolution in cochlear hearing losses. The procedure was designed to restore normal relative loudness contributions from each frequency band of input speech. Prescribed frequency responses had less steep bass cut than recommended by either the Prescription of Gain/Output or the National Acoustic Laboratories' procedures, regardless of various model assumptions. Prescribed overall gain depended on the loudness growth assumed in the model. In cases where auditory filters are wider than normal and loudness recruitment is complete, the procedure yielded a nonlinear relation between hearing aid gain and hearing loss: Required insertion gain (in dB) was 25 to 30% of hearing threshold loss (in dB HL) for mild to moderate losses, but this percentage increased for more severe impairments. For cases with incomplete loudness recruitment, the model prescribed that insertion gain should be 40 to 50% of hearing threshold loss for a wide range of impairments.
Design and performance of a new line focus geometry for x-ray laser experiments (1987)

A novel optical line focus system using a lens and off-axis mirror combination which allows a high quality line focus to be obtained has been developed for x-ray laser research. By irradiation of fiber and thin foil targets with a high power laser various experimental observations show the excellent performance of this new scheme.
Low Voltage Analog Circuit Design Techniques: A Tutorial (2000)

Low voltage (LV) analog circuit design techniques are addressed in this tutorial. In particular, (i) technology considerations; (ii) transistor model capable to provide performance and power tradeoffs; (iii) low voltage implementation techniques capable to reduce the power supply requirements, such as bulk-driven, floating-gate, and self-cascode MOSFETs; (iv) basic LV building blocks; (v) multi-stage frequency compensation topologies; and (vi) fully-differential and fully-balanced systems. key words: analog circuits, amplifiers, transistor model, bulkdriven, floating-gate, self-cascode, NGCC frequency compensation, fully-differential and fully-balanced systems.
Canalicular communication in the cortices of human long bones (1985)

A scanning electron microscopic (SEM) cast method that has been utilized to examine the internal structure of dentine was modified to examine canalicular communications in the cortices of a human femur and ulna. Although some preparations in which all of the matrix was removed were examined, etched preparations were found to be the most informative. Casts of lacunae and canaliculi along with the underlying matrix could be visualized in these preparations. In the femur, whose cortex exhibited a typical lamellar pattern, canalicular communication was seen between first and second generation osteons and occasionally between osteons and interstitial regions. The interstitial regions in the ulna appeared to be primarily woven rather than lamellar bone. Extensive communication between the outermost lacunae of osteons and interstitial regions was observed in the ulna.
In vivo formation of oxidized DNA bases in tumor promoter-treated mouse skin. (1991)

There has been a paucity of evidence showing that 12-O-tetradecanoyl-phorbol-13-acetate (TPA), a potent tumor promoter, causes DNA damage in vivo. We show that oxidized DNA bases are formed in the epidermis of TPA-treated SENCAR mice in a dose- and time-dependent manner. As measured by high-performance liquid chromatography and acetylation of nucleosides with [3H]acetic anhydride, these oxidized DNA derivatives include cis-thymidine glycol, 5-hydroxymethyl-2'-deoxyuridine, and 8-hydroxyl-2'-deoxyguanosine. Their maximal formation induced by a single TPA dose occurred within 6-8 h (a 2-5-fold increase). The level of 8-hydroxyl-2'-deoxyguanosine was the lowest (3.2/10(5) bases) and remained almost unchanged for 18 h; thymidine glycol (29.1/10(4) bases) and 5-hydroxymethyl-2'-deoxyuridine (17.3/10(4) bases) declined gradually but were still above controls at 24 h. Reapplication of TPA 20 h after the first dose (time of the maximal polymorphonuclear leukocyte infiltration) enhanced the net formation of 8-hydroxyl-2'-deoxyguanosine by 3.8-fold (P less than 0.05), of cis-thymidine glycol by 1.9-fold (P less than 0.001), and of 5-hydroxymethyl-2'-deoxyuridine by 2.0-fold (P less than 0.01), as compared to those maximally produced by a single TPA dose. Thus, the infiltration of polymorphonuclear leukocytes into TPA-treated mouse skin, which was corroborated by histological examination and the presence of polymorphonuclear leukocyte-specific myeloperoxidase, might play an important role in TPA-induced DNA oxidation in vivo. Our findings provide proof that tumor promoters can induce genetic modification in vivo that is oxidative in nature. Hence, formation of oxidized DNA bases may be responsible for the genetic effects of tumor promoters in carcinogenesis.
Chalcones and Dihydrochalcones Augment TRAIL-Mediated Apoptosis in Prostate Cancer Cells (2010)

Chalcones and dihydrochalcones exhibit chemopreventive and antitumor activity. TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) is a natural endogenous anticancer agent. We examined the cytotoxic and apoptotic effect of chalcones and dihydrochalcones on TRAIL-mediated apoptosis in LNCaP prostate cancer cells. The cytotoxicity was evaluated by the MTT and LDH assays. The apoptosis was detected using annexin V-FITC by flow cytometry and fluorescence microscopy. The DeltaPsim was evaluated using DePsipher staining by fluorescence microscopy. Our study showed that two tested chalcones (chalcone and 2',6'dihydroxy-4'-methoxychalcone) and three dihydrochalcones (2',6'-dihydroxy-4'4-dimethoxydihydrochalcone, 2',6'-dihydroxy-4'-methoxydihydro- chalcone, and 2',4',6'-trihydroxydihydrochalcone, called phloretin) markedly augmented TRAIL-induced apoptosis and cytotoxicity in LNCaP cells and confirmed the significant role of chalcones in chemoprevention of prostate cancer.
Failure Localization and Correlation of High-Speed Tension and Impact Tests of Strain-Hardening Cement-Based Composites (2017)

Mechanical properties of strain-hardening cement-based composites (SHCC) subjected to impact and high-speed tensile loading were studied. The impact test setup was based on a free-fall drop weight on a three-point bending specimen. A servohydraulic high-speed tensile machine was used for tension tests. As the input impact energy increased from 6.7 to 67 J, absorbed energy increased from 0.7 to 3.6 J and remained constant at that level. Ultimate load and maximum deflection also increased with increasing input energy. Uniaxial tension tests on SHCC specimens were conducted at strain rates of 25, 50, and 100 s−1. Increases in tensile strength and strain capacity were observed with increasing strain rate. Digital image correlation (DIC) method was used to measure the full-field deformation in addition to the nature of the localized strain and shear lag region near transverse cracks. An analytical model was used to correlate the tensile and flexural impact responses and address the effect of localized failure on the overall sample response. The results indicate that the two test methods of impact and high-speed tension can be correlated by using a constitutive material model and that the correlation of the material properties under increasing strain rate with an increase in input impact energy can be addressed through cracking and size of the localization zone.
Engineering dynamic real-time distributed systems: architecture, system description language, and middleware (2002)

The paper presents an architectural framework and algorithms for engineering dynamic real-time distributed systems using commercial off-the-shelf technologies. In the proposed architecture, a real-time system application is developed in a general-purpose programming language. Further, the architectural-level description of the system such as composition and interconnections of application software and hardware, and the operational requirements of the system such as timeliness and survivability are specified in a system description language. The specification of the system is automatically translated into an intermediate representation (IR) that models the system in a platform-independent manner. The IR is augmented with dynamic measurements of the system by a language runtime system to produce a dynamic system model. The dynamic model is used by resource management middleware strategies to perform resource management that achieves timeliness and survivability requirements. We present two classes of algorithms: predictive and availability-based, for performing resource allocation. To validate the viability of the approach, we use a real-time benchmark application that functionally approximates dynamic real-time command and control systems. The benchmark results illustrate that the middleware is able to achieve the desired timeliness requirements during a number of load situations. Furthermore, availability-based allocation algorithms perform resource allocation less frequently, whereas predictive algorithms give a better steady state performance for the application.
Facile Syntheses of Novel Acyclic Polycarboxylic Acids (2005)

The synthesis of novel di- and tricarboxylic acids is described. Starting from diethanolamine, a series of N-substituted diethanol derivatives were prepared which were converted in the subsequent reaction step into the corresponding carboxylic acids by treatment with chloroacetic acid. N,N-bis[2- (carboxymethoxy)ethyl]glycine was obtained by N-alkylation of glycine ethylester with ethyl 2-(2- bromoethoxy)acetate