gebhart/patrepeval huggingface dataset:
The Iodine Satellite (iSat) Project Development Towards Critical Design Review (2015)

Despite the prevalence of small satellites in recent years, the systems flown to date have very limited propulsion capability. SmallSats are typically secondary payloads and have significant constraints for volume, mass, and power in addition to limitations on the use of hazardous propellants or stored energy. These constraints limit the options for SmallSat maneuverability. NASA's Space Technology Mission Directorate approved the iodine Satellite flight project for a rapid demonstration of iodine Hall thruster technology in a 12U (cubesat units) configuration under the Small Spacecraft Technology Program. The mission is a partnership between NASA MSFC, NASA GRC, and Busek Co, Inc., with the Air Force supporting the propulsion technology maturation. The team is working towards the critical design review in the final design and fabrication phase of the project. The current design shows positive technical performance margins in all areas. The iSat project is planned for launch readiness in the spring of 2017.
Total synthesis and structure assignment of the antitumor antibiotic aranorosin (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTotal synthesis and structure assignment of the antitumor antibiotic aranorosinPeter Wipf, Yuntae Kim, and Paul C. FritchCite this: J. Org. Chem. 1993, 58, 25, 7195–7203Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/jo00077a050https://doi.org/10.1021/jo00077a050research-articleACS PublicationsRequest reuse permissionsArticle Views1523Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
H2-K <sup>b</sup> and H2-D <sup>b</sup> regulate cerebellar long-term depression and limit motor learning (2009)

There are more than 50 class I MHC (MHCI) molecules in the mouse genome, some of which are now known to be expressed in neurons; however, the role of classical MHCI molecules in synaptic plasticity is unknown. We report that the classical MHCI molecules, H2-K(b) and H2-D(b), are co-expressed by Purkinje cells (PCs). In the cerebellum of mice deficient for both H2-K(b) and H2-D(b) (K(b)D(b-/-)), there is a lower threshold for induction of long-term depression (LTD) at parallel fiber to PC synapses. This change may be a result of additional glutamate release observed at K(b)D(b-/-) CF to PC synapses, which are thought to "train" the cerebellar circuit. A behavioral correlate of cerebellar LTD is motor learning; acquisition and retention of a Rotarod behavioral task is significantly better in K(b)D(b-/-) mice than in WT cohorts. These physiological and behavioral phenotypes in K(b)D(b-/-) mice reveal a surprising role for classical MHCI molecules in synaptic plasticity and motor learning.
Light scattering by film grain noise: application to grey level optical pseudocoloring (1983)

An optical method for grey level pseudocolor encoding in real time based on the scattering properties of film grain noise is proposed. The light scattered by the film is studied by means of a lognormal model applied to the wave front emerging from the object. Three beams, each with a primary color, are used to illuminate the original black-and-white picture, giving a pseudocolored image.
Fractionation of neurophysin by molecular-sieve and ion-exchange chromatography (1967)

Neurophysin has been separated into seven distinct protein fractions. One of these components had no hormone-binding activity. The fractions that had hormone-binding activity were similar in amino acid composition: their cystine content was in the range 11.5-14.5%. The major component, neurophysin-M, was distinguished from the protein isolated by van Dyke by the presence of methionine and the absence of histidine. Neurophysin-M binds both oxytocin and vasopressin with similar affinities.
Growth of ZnS by Metalorganic Chemical Vapor Deposition (1983)

ZnS epilayers are grown on GaP and GaAs substrates by a low pressure metalorganic chemical vapor deposition technique using dietylzinc (DEZ) or dimethylzinc (DMZ) and H 2 S as source materials. Good epitaxial layers of ZnS are grown at a substrate temperature T G of 370 to 400°C at a flow rate ratio, [H 2 S]/[DEZ] or [DMZ]≃3.0. A typical growth rate of ZnS layers at T G =375°C is ∼4 µm/hr for the DEZ/H 2 S system and ∼3 µm/hr for the DMZ/H 2 S system.
A New Algorithm for Rapid Tracking of Approximate Maximum Power Point in Photovoltaic Systems (2004)

This paper presents a new algorithm for tracking maximum power point in photovoltaic systems. This is a fast tracking algorithm, where an initial approximation of maximum power point is (MPP) quickly achieved using a variable step-size. Subsequently, the exact maximum power point can be targeted using any conventional method like the hill-climbing or incremental conductance method. Thus, the drawback of a fixed small step-size over the entire tracking range is removed, resulting in reduced number of iterations and much faster tracking compared to conventional methods. The strength of the algorithm comes from the fact that instead of tracking power, which does not have a one-to-one relationship with duty cycle, it tracks an intermediate variable /spl beta/, which has a monotonically increasing, one-to-one relationship. The algorithm has been verified on a photovoltaic system modeled in Matlab-Simulink software. The algorithm significantly improves the efficiency during the tracking phase as compared to a conventional algorithm. It is especially suitable for fast changing environmental conditions. The proposed algorithm can be implemented on any fast controller such as the digital signal processor. All the details of this study are presented.
Natriuretic Peptides: An Update on Bioactivity, Potential Therapeutic Use, and Implication in Cardiovascular Diseases (2008)

The natriuretic peptide system includes three known peptides: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). They contribute to the regulation of cardiovascular homeostasis through diuretic, natriuretic, and vasodilatory properties. Among them, ANP has received particular attention because of its effects on blood pressure regulation and cardiac function. Although the potential for its therapeutic application in the treatment of hypertension and heart failure has been evaluated in several experimental and clinical investigations, no pharmacological approach directly targeted at modulation of ANP levels has ever reached the stage of being incorporated into clinical practice. Recently, ANP has also received attention as being a possible cardiovascular risk factor, particularly in the context of hypertension, stroke, obesity, and metabolic syndrome. Abnormalities in either peptide levels or peptide structure are thought to underlie its implied role in mediating cardiovascular diseases. Meanwhile, BNP has emerged as a relevant marker of left ventricular (LV) dysfunction and as a useful predictor of future outcome in patients with heart failure. This review deals with the major relevant findings related to the cardiovascular and metabolic effects of natriuretic peptides, to their potential therapeutic use, and to their role in mediating cardiovascular diseases.
Circulatie van kennis in de zeventiende eeuw en nu (2008)

met een project om oude publicaties te digitaliseren en via internet toegankelijk te maken.Een half miljoen pagina's staan op het programma.
Experimental study of a self-powered and sensing MR-damper-based vibration control system (2011)

The paper deals with a semi-active vibration control system based on a magnetorheological (MR) damper. The study outlines the model and the structure of the system, and describes its experimental investigation. The conceptual design of this system involves harvesting energy from structural vibrations using an energy extractor based on an electromagnetic transduction mechanism (Faraday's law). The system consists of an electromagnetic induction device (EMI) prototype and an MR damper of RD-1005 series manufactured by Lord Corporation. The energy extracted is applied to control the damping characteristics of the MR damper.
Antenna gain against interference in CDMA macrodiversity systems (2002)

In a multiantenna system, there is a potential antenna gain against interference, in addition to the diversity gain achieved against fading. It is well known that in order to attain most of the diversity gain (against fading), the antenna elements should be placed apart with a distance (many times) greater than the wavelength=[speed of light]/[frequency] of the carrier. The results presented in this paper indicate that in order to attain most of the antenna gain (against interference) in the reverse-link of finite-bandwidth interference-limited CDMA systems, the interantenna distance should be (many times) greater than a new parameter which is defined as the chiplength=[speed of light]/[chip rate] of the spreading code.
Gate sizing for cell library-based designs (2007)

With increasing time-to-market pressure and shortening semiconductor product cycles, more and more chips are being designed with library-based methodologies. In spite of this shift, the problem of discrete gate sizing has received significantly less attention than its continuous counterpart. On the other hand, cell sizes of many realistic libraries are sparse, for example, geometrically spaced, which makes the nearest rounding approach inapplicable as large timing violations may be introduced. Therefore, it is highly desirable to design an effective algorithm to handle this discrete gate sizing problem. Such an algorithm is proposed in this paper. The algorithm is a continuous solution guided dynamic programming approach. A set of novel techniques, such as locality sensitive hashing based solution selection and stage pruning, are also proposed to accelerate the algorithm and improve the solution quality. Our experimental results demonstrate that (1) nearest rounding approach often leads to large timing violations and (2) compared to the well-known Coudert's approach, the new algorithm saves 9% - 31% in area cost while still satisfying the timing constraint.
Software Model of the Signal Processing Unit in the Conventional Radar (2005)

Some results of research project related to software model of the signal processing unit in the conventional radar was presented in this paper. Also, the concept of estimation of Doppler frequency for real targets on the basis of FFT and MUSIC is proposed
Flame spray-pyrolyzed vanadium oxide nanoparticles for lithium battery cathodes (2009)

Vanadium pentoxide (V2O5) nanoparticles (30-60 nm) were made by a one-step and scalable flame spray pyrolysis (FSP) process. Optimization of the FSP processing conditions (precursor concentration and injection rate) enhanced the electrochemical performance of these nanoparticles. Increasing the cut-off potential for discharging from 1.5 to 2.5 V vs. Li/Li+ improved the cycle life of these V2O5 nanoparticles. Particles with the lowest specific surface area (approximately 32 m2 g(-1)) and highest phase purity (up to 98 wt%) showed excellent cyclability between 2.5 and 4.0 V vs. Li/Li+, retaining a specific charge of 110 mAh g(-1) beyond 100 cycles at a specific current of 100 mA g(-1), and also superior specific charge of 100 mAh g(-1) at specific current up to 20C rate (or 2000 mA g(-1)).
Physical characterization of polyethylene glycols by thermal analytical technique and the effect of humidity and molecular weight. (2010)

Polyethylene glycols (PEGs) are well known as excipients in tablet dosage formulations. PEGs are generally known to be inert and have very few interactions with other components in the solid dosage forms. However, the physical nature of PEGs and how they affect the disintegration of tablets is not very well understood for the different molecular weights of PEGs. The knowledge of the effect of molecular weight of PEGs on their physical properties and the effect of humidity on the physical properties of PEGs are important parameters for the choice of a PEG to be acceptable as an excipient in pharmaceutical formulations. This study was done to determine the precision of the DSC physical properties for a wide range of PEGs with varying molecular weights from 194 to 23000 daltons. Nine different molecular weights of PEGs were examined in a DSC controlled Heat-Cool-Heat-Cool-Heat (HCHCH) cycle and the observed reproducible values of melting temperature, heat of fusion, crystallization temperature and the heat of crystallization were compared with values obtained from the literature and the observed percent crystallinity was again cross-checked by X-ray Diffraction (XRD) studies. The comparison values indicated acceptable precision. This study was also done to check the effect of humidity on the DSC physical properties for the entire range of PEGs. The results indicated that humidity probably has a higher effect on the physical properties of the low molecular weight PEGs as compared to the high molecular weight PEGs.
How big is the myelinating orchestra? Cellular diversity within the oligodendrocyte lineage: facts and hypotheses (2014)

Since monumental studies from scientists like His, Ramón y Cajal, Lorente de Nó and many others have put down roots for modern neuroscience, the scientific community has spent a considerable amount of time, and money, investigating any possible aspect of the evolution, development and function of neurons. Today, the complexity and diversity of myriads of neuronal populations, and their progenitors, is still focus of extensive studies in hundreds of laboratories around the world. However, our prevalent neuron-centric perspective has dampened the efforts in understanding glial cells, even though their active participation in the brain physiology and pathophysiology has been increasingly recognized over the years. Among all glial cells of the central nervous system (CNS), oligodendrocytes (OLs) are a particularly specialized type of cells that provide fundamental support to neuronal activity by producing the myelin sheath. Despite their functional relevance, the developmental mechanisms regulating the generation of OLs are still poorly understood. In particular, it is still not known whether these cells share the same degree of heterogeneity of their neuronal companions and whether multiple subtypes exist within the lineage. Here, we will review and discuss current knowledge about OL development and function in the brain and spinal cord. We will try to address some specific questions: do multiple OL subtypes exist in the CNS? What is the evidence for their existence and those against them? What are the functional features that define an oligodendrocyte? We will end our journey by reviewing recent advances in human pluripotent stem cell differentiation towards OLs. This exciting field is still at its earliest days, but it is quickly evolving with improved protocols to generate functional OLs from different spatial origins. As stem cells constitute now an unprecedented source of human OLs, we believe that they will become an increasingly valuable tool for deciphering the complexity of human OL identity.
Binding of ethidium bromide to a DNA triple helix. Evidence for intercalation. (1991)

The interaction of ethidium, a DNA intercalator, with the poly(dA).poly(dT) duplex and the poly (dA).2poly(dT) triplex has been investigated by a variety of spectrophotometric and hydrodynamic techniques. The fluorescence of ethidium is increased when either the duplex or triplex form is present. Binding constants, determined from absorbance measurements, indicate that binding to the triple helical form is substantially stronger than to the duplex, with a larger binding site size (2.8 base triplets compared to 2.4 base pairs). Furthermore, while binding to poly(dA).poly(dT) shows strong positive cooperativity, binding to the triplex is noncooperative. Thermal denaturation experiments demonstrate that ethidium stabilizes the triple helix. Binding to either form induces a weak circular dichroism band in the visible wavelength region, while in the region around 310 nm, there is a band that is strongly dependent on the degree of saturation of the duplex, and which is positive for the duplex but negative for the triplex. Both fluorescence energy transfer and quenching studies provide evidence of intercalation of ethidium in both duplex and triplex complexes. Binding of ethidium leads to an initial decrease in viscosity for both the duplex and triplex structures, followed by an increase, which is greater for the duplex. Taken together, these results strongly suggest that ethidium binds to the poly (dA).2poly(dT) triple helix via an intercalative mechanism.
Dual-polarization and dual-mode orbital angular momentum radio vortex beam generated by using reflective metasurface (2016)

Abstract A metasurface, which is composed of printed cross-dipole elements with different arm lengths, is designed, fabricated, and experimentally demonstrated to generate orbital angular momentum (OAM) vortex waves of dual polarizations and dual modes in the radio frequency domain simultaneously. The prototype of a practical metasurface is fabricated and measured to validate the results of theoretical analysis and design at 5.8 GHz. Numerical and experimental results verify that vortex waves with dual OAM modes and dual polarizations can be flexibly generated by using a reflective metasurface. The proposed method paves a way to generate diverse OAM vortex waves for radio frequency and microwave wireless communication applications.
A monoclonal antibody against the type II isotype of beta-tubulin. Preparation of isotypically altered tubulin. (1988)

Mammalian brain tubulin consists of several isotypes of alpha and beta subunits that separate on polyacrylamide gels into three electrophoretic classes, designated alpha, beta 1, and beta 2. It has not been possible hitherto to resolve the different isotypes in a functional form. To this end, we have now isolated a monoclonal antibody, using as an immunogen a chemically synthesized peptide corresponding to the carboxyl-terminal sequence of the major tubulin isotype (type II) found in the beta 1-tubulin electrophoretic fraction. The antibody binds to beta 1 but not to alpha or beta 2. When pure tubulin from bovine brain is passed through an immunoaffinity column made from the anti-type II antibody, the tubulin that elutes in the unbound fraction is enriched greatly for the beta 2 electrophoretic variant. The tubulin that binds to the column appears to contain only alpha and beta 1, not beta 2. When these tubulin fractions are characterized by immunoblotting using the anti-type II antibody, the antibody binds only to the beta 1 band in the bound fraction, not to the beta 1 band in the unbound fraction. Using polyclonal antibodies generated against the carboxyl-termini of types I, III, and IV, we demonstrate that the beta 1 electrophoretic species is comprised of isotypes I, II, and IV, whereas the beta 2 variant is comprised exclusively of type III beta-tubulin. Further, we calculate that beta-tubulin in purified bovine brain tubulin is comprised of 3% type I, 58% type II, 25% type III, and 13% type IV tubulins.
ChemInform Abstract: Synthesis of Functionalized 2‐Salicyloylfurans, Furo[3,2‐b]chromen‐9‐ones and 2‐Benzoyl‐8H‐thieno[2,3‐b]indoles by One‐Pot Cyclizations of 3‐Halochromones with β‐Ketoamides and 1,3‐Dihydroindole‐2‐thiones. (2015)

Abstract Title compounds are prepared under mild conditions by reaction of 3‐halochromones with β‐ketoamides and dihydroindolethiones.
New synthetic route to the hydridospherosiloxanes Oh-H8Si8O12 and D5h-H10Si10O15 (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew synthetic route to the hydridospherosiloxanes Oh-H8Si8O12 and D5h-H10Si10O15Pradyot A. AgaskarCite this: Inorg. Chem. 1991, 30, 13, 2707–2708Publication Date (Print):June 1, 1991Publication History Published online1 May 2002Published inissue 1 June 1991https://pubs.acs.org/doi/10.1021/ic00013a002https://doi.org/10.1021/ic00013a002research-articleACS PublicationsRequest reuse permissionsArticle Views1379Altmetric-Citations195LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An intelligent BiCMOS/DMOS quad 1-A high-side switch (1990)

A fully protected quad high-side DMOS switch has been realized using a BiCMOS/DMOS process. A bipolar multiplier cell calculates and limits instantaneous power dissipated by each 0.8- Omega DMOS power switch to 13 W. The integrated circuit shuts down to protect itself if a safe temperature or operating voltage is exceeded. A thermal warning is provided when the junction temperature rises to within 20 degrees C of the shutdown temperature such that an orderly system turn-off occurs. A serial output data pin reports status information including channel on/off, open and shorted load faults, warning and shutdown temperatures, and an overvoltage condition. The circuit withstands a supply voltage of 60 V and operates from 6 to 32 V. The IC can be permanently connected to the power while drawing no DC current in the standby mode. The device fits into a 20-pin dual-in-line package having the die-attach paddle and the center four pins of the lead frame being a continuous strip of metal providing a low thermal resistance path from which to extract heat from the output switches.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>