gebhart/patrepeval huggingface dataset:
Parallel architectures for computing cyclic convolutions (1983)

In the paper two parallel architectural structures are developed to compute one-dimensional cyclic convolutions. The first structure is based on the Chinese remainder theorem and Kung's pipelined array. The second structure is a direct mapping from the mathematical definition of a cyclic convolution to a computational architecture. To compute a d-point cyclic convolution the first structure needs d/2 inner product cells, while the second structure and Kung's linear array require d cells. However, to compute a cyclic convolution, the second structure requires less time than both the first structure and Kung's linear array. Another application of the second structure is to multiply a Toeplitz matrix by a vector. A table is listed to compare these two structures and Kung's linear array. Both structures are simple and regular and are therefore suitable for VLSI implementation.
The metabolism of 1,3-cyclohexadiene by liver microsomal mono-oxygenase (1982)

1. 1,3-Cyclohexadiene exhibits type I binding spectra with microsomal cytochrome P-450 of either untreated, or phenobarbital- or 3-methylcholanthrene-treated mice. In all cases, two values of Ks can be measured, indicating a different affinity of 1,3-cyclohexadiene towards the cytochrome P-450 species. 2. Mouse-liver microsomal mono-oxygenase metabolizes 1,3-cyclohexadiene to the corresponding mono-epoxide, which is rapidly hydrolysed to trans-3-cyclohexene-1,2-diol and trans-2-cyclohexene-1,4-diol. This hydrolysis was proved to be essentially nonenzymic. 3. A simple gas-chromatographic method was used to quantify the diols and to determine the kinetic constants (Km and Vmax) of 1,3-cyclohexadiene mono-epoxidase. 4. Epoxide formation, as determined by diol production from 1,3-cyclohexadiene metabolism, was NADPH- and O2-dependent and was inhibited by CO and SKF-525A.
Model-Based Analysis of Microservice Resiliency Patterns (2020)

Microservice application developers try to mitigate the impact of partial outages typically by implementing service-to-service interactions that use well-known resiliency patterns, such as Retry, Fail Fast, and Circuit Breaker. However, those resiliency patterns-as well as their available open-source implementations-are often documented informally, leaving it up to application developers to figure out when and how to use those patterns in the context of a particular microservice application. In this paper, we take a first step towards improving on this situation by introducing a model checking-based approach in which we use the PRISM probabilistic model checker to analyze the behavior of the Retry and Circuit Breaker resiliency patterns as continuous-time Markov chains (CTMC). This approach has enabled us to quantify the impact of applying each resiliency pattern on multiple quality attributes, as well as to determine how to best tune their parameters to deal with varying service availability conditions, in the context of a simple client-service interaction scenario.
SYSTEMS OF MATING. I. THE BIOMETRIC RELATIONS BETWEEN PARENT AND OFFSPRING (1921)

Page 117, next to last line, for (see PDF)

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Augmentation in the expression of a ribosomal protein associated with transformation (1998)

Using differential hybridization technique, cDNA that was a partial sequence of rat ribosomal protein L41 was isolated from fos- and src-transfected rat fibroblast 3Y1. The cDNA was named #31. Subsequently, the human counterpart(named hm3168) was cloned from a human melanoma cell line(M14) and the amino acid sequence deduced from the cDNA proved to be identical to that of HG-12. The gene expression of hm3168 was inducible by serum-stimulation. It reveals the possible up-regulation of the transcription via fos-mediated signal transduction. Northern-blot and Western-blot analyses showed a large expression of the #31 gene in the rat transformed cell lines.
Multi camera person tracking applying a graph-cuts based foreground segmentation in a homography framework (2009)

Reliable tracking of objects is an inevitable prerequisite for automated video surveillance systems. As most object detection methods, which are based on machine learning, require adequate data for the application scenario, foreground segmentation is a popular method to find possible regions of interest. These usually require a specific learning phase and adaptation over time. In this work we will present a novel approach based on graph cuts, which outperforms most standard algorithms. It is commonly agreed that occlusions can only be resolved in multi camera environments. Applying multi layer homography will enable us to robustly detect and track objects applying only foreground data, resulting in a high tracking performance.
Hybrid quantum-classical computing with applications to computer graphics (2005)

Quantum computing (QC) has become an important area of research in computer science because of its potential to provide more efficient algorithmic solutions to certain problems than are possible with classical computing (CC). In particular, QC is able to exploit the special properties of quantum superposition to achieve computational parallelism beyond what can be achieved with parallel CC computers. However, these special properties are not applicable for general computation. Therefore, we propose the use of "hybrid quantum computers" (HQCs) that combine both classical and quantum computing architectures in order to leverage the benefits of both. We demonstrate how an HQC can exploit quantum search to support general database operations more efficiently than is possible with CC. Our solution is based on new quantum results that are of independent significance to the field of quantum computing. More specifically, we demonstrate that the most restrictive implications of the quantum No-Cloning Theorem can be avoided through the use of semiclones. In this paper we discuss specific applications of quantum search to problems in computational geometry, simulation, and computer graphics.
ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux (2003)

ATP-binding cassette transporter 1 (ABCA1), the defective transporter in Tangier disease, binds and promotes cellular cholesterol and phospholipid efflux to apolipoprotein I (apoA-I). Based on a high degree of sequence homology between ABCA1 and ABCA7, a transporter of unknown function, we investigated the possibility that ABCA7 might be involved in apolipoprotein binding and lipid efflux. Similarly to cells expressing ABCA1, HEK293 cells overexpressing ABCA7 showed specific binding and cross-linking of lipid-poor apoA-I. ABCA7 expression increased cellular phosphatidylcholine and sphingomyelin efflux to apoA-I in a manner similar to ABCA1 but had no effect on cholesterol efflux. Western analysis showed a high protein level of ABCA7 in mouse spleen, lung, adrenal, and brain but low expression in liver. In contrast to ABCA1, ABCA7 showed moderate basal mRNA and protein levels in macrophages and lymphocytes but no induction by liver X receptor activation. These studies show that ABCA7 has the ability to bind apolipoproteins and promote efflux of cellular phospholipids without cholesterol, and they suggest a possible role of ABCA7 in cellular phospholipid metabolism in peripheral tissues.
Synthesis of I-125 labeled photoaffinity rapamycin analogs (1996)

Two no-carrier-added 125I-labeled photoaffinity rapamycin analogs were prepared: 7-demethoxy-7-(4-azido-3-125I-benzyloxy)rapamycin (2) and its C28–C29 seco analog 3. The key reactions of the synthesis were substitution of the C7 methoxyl of rapamycin (1) with 4-azido-3-tributylstannylbenzyloxy group, exchange of tributyltin with 125I using Na125I and Chloramine-T, and a ZnCl2 mediated retro-Aldol cleavage of the C28–C29 bond of rapamycin.
2120. Every spherical triangle is isosceles (1950)

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Cloud computing based solutions for monitoring the supply chain of fish and fishery products (2017)

This research contributes to the improvement of the increasing requirements for the improving the traceability and transparency of fish and fishery products, which are subject of rapid deterioration during the supply chain. The research study the requirements for the fish and fishery products traceability system, taking the consideration the European and national legislation for food safety and security, the supply chain stakeholders, and the technology of fish and fishery products. The paper presents general framework of a cloud computing based traceability systems, which is designed in order to trace the fish and fishery products in the supply chain.
Composition of the Surface Proteome of<i>Anaplasma marginale</i>and Its Role in Protective Immunity Induced by Outer Membrane Immunization (2008)

Surface proteins of tick-borne, intracellular bacterial pathogens mediate functions essential for invasion and colonization. Consequently, the surface proteome of these organisms is specifically relevant from two biological perspectives, induction of protective immunity in the mammalian host and understanding the transition from the mammalian host to the tick vector. In this study, the surface proteome of Anaplasma marginale, a tick-transmitted bacterial pathogen, was targeted by using surface-specific cross-linking to form intermolecular bonds between adjacent proteins. Liquid chromatography and tandem mass spectroscopy were then employed to characterize the specific protein composition of the resulting complexes. The surface complexes of A. marginale isolated from erythrocytes of the mammalian host were composed of multiple membrane proteins, most of which belong to a protein family, pfam01617, which is conserved among bacteria in the genus Anaplasma and the closely related genus Ehrlichia. In contrast, the surface proteome of A. marginale isolated from tick cells was much less complex and contained a novel protein, AM778, not identified within the surface proteome of organisms from the mammalian host. Immunization using the cross-linked surface complex induced protection against high-level bacteremia and anemia upon A. marginale challenge of cattle and effectively recapitulated the protection induced by immunization with whole outer membranes. These results indicate that a surface protein subset of the outer membrane is capable of inducing protective immunity and serves to direct vaccine development. Furthermore, the data support that remodeling of the surface proteome accompanies the transition between mammalian and arthropod hosts and identify novel targets for blocking transmission.
Energy and Food Irradiation (1978)

Abstract : This paper shows that significant energy savings can be obtained by use of irradiation preservation. The energy used in food systems in the US amounts to about 16.5% of the total energy. An analysis of the energy used in the many steps of the food irradiation process found that irradiation pasteurization uses only 21 kJ/kg, radappertization 157 kJ/kg, which is much less than the energy used in the other food processes. A comparison has also been made with other methods of preserving, distributing, and preparing the meat for servings. It is found that food irradiation can save significant amounts of energy. In the case of heat sterilized and radiation sterilized meats, the largest fraction of energy used is in the packaging, while in the frozen meats, the largest energy consumption is by refrigeration in the distribution channels and in the homes.
Designing a generalized 3D carousel view (2005)

In this paper we describe a 3D carousel view design. We take the basic carousel model and elaborate it to hold an arbitrary number of items in an efficient manner. We equip this model with various interaction methods and a novel component: the termination marker. We also explore more detailed design issues, like animation, by implementing a prototype. We report essential user feedback and how it affected our design.
Point Mutation in Exon 12 of the Receptor Tyrosine Kinase Proto-oncogene RET in Ondine-Hirschsprung Syndrome (1998)

A 5-year-old girl with congenital central hypoventilation syndrome associated with Hirschsprung's disease (Ondine-Hirschsprung syndrome) representing a missense mutation in exon 12 of the receptor tyrosine kinase (RET) proto-oncogene is reported. Using a direct sequencing technique, genomic DNA obtained from the patient's peripheral leukocytes was analyzed for its nucleotide sequences in all 20 exons of the RET proto-oncogene, seven regions of the 1st to the 7th exon of the endothelin-B receptor gene and endothelin 3 gene, including sequences corresponding to proteolytic cleavage sites. The analysis revealed that adenine at the 2116th base in the 12th exon in the RET proto-oncogene was substituted by guanine, supposedly resulting in a mutation of Thr 706 to Ala. No other mutational change was observed in the gene examined in this case. Mutation analysis has not been described previously on the gene in this disease complex. Mutation in this case might impair the maturation of the tyrosine kinase protein and subsequently cause neurocristopathy supposedly originating from the neural crest.
Housing Densities and Standards (1966)

(1966). Housing Densities and Standards. Architectural Science Review: Vol. 9, No. 1, pp. 6-15.
Fast Prediction for Large-Scale Kernel Machines (2014)

Kernel machines such as kernel SVM and kernel ridge regression usually con-struct high quality models; however, their use in real-world applications remains limited due to the high prediction cost. In this paper, we present two novel in-sights for improving the prediction efficiency of kernel machines. First, we show that by adding “pseudo landmark points ” to the classical Nyström kernel approxi-mation in an elegant way, we can significantly reduce the prediction error without much additional prediction cost. Second, we provide a new theoretical analysis on bounding the error of the solution computed by using Nyström kernel approxima-tion method, and show that the error is related to the weighted kmeans objective function where the weights are given by the model computed from the original ker-nel. This theoretical insight suggests a new landmark point selection technique for the situation where we have knowledge of the original model. Based on these two insights, we provide a divide-and-conquer framework for improving the predic-tion speed. First, we divide the whole problem into smaller local subproblems to reduce the problem size. In the second phase, we develop a kernel approximation based fast prediction approach within each subproblem. We apply our algorithm to real world large-scale classification and regression datasets, and show that the proposed algorithm is consistently and significantly better than other competitors. For example, on the Covertype classification problem, in terms of prediction time, our algorithm achieves more than 10000 times speedup over the full kernel SVM, and a two-fold speedup over the state-of-the-art LDKL approach, while obtaining much higher prediction accuracy than LDKL (95.2 % vs. 89.53%). 1
A PC-based radiation monitor (2018)

A low-cost high-precision system for monitoring the radioactivity level has been developed on the basis of a personal computer using the modern concept of virtual instrumentation. The proposed device has certain advantages over conventional systems: user-defined functions, open system architecture, multitask operation support, simple data sharing between different applications, convenient graphical users interface, easy network connection, full control of the system operation, complete and perfect presentation of the results of measurements, and reasonable price.
Uniform tiling with electrical resistors (2011)

The electric resistance between two arbitrary nodes on any \ninfinite lattice structure of resistors that is a periodic \ntiling of space is obtained. Our general approach is based on \nthe lattice Green's function of the Laplacian matrix associated \nwith the network. We present several non-trivial examples to \nshow how efficient our method is. Deriving explicit resistance \nformulas it is shown that the Kagome, diced and decorated \nlattice can be mapped to the triangular and square lattice of \nresistors. Our work can be extended to the random walk problem \nor to electron dynamics in condensed matter physics.
Precipitation of oxygen in dislocation-free silicon (1979)

The precipitation of oxygen in bulk dislocation-free Czochralski silicon subjected to isothermal annealing at temperatures between 400 and 1100 °C is studied by means of infrared spectroscopy and transmission electron microscopy. From the changes in the infrared spectra observed after heat treatment it is concluded that (i) for low annealing temperatures (400 to 750°C) the precipitates consist of amorphous SiOx (x < 2) which with rising temperature is transformed into amorphous SiO2, (ii) at medium annealing temperatures (750 to 950 °C) α-cristobalite precipitates are formed, which (iii) at high annealing temperatures (950 to 1100 °C) are converted in amorphous SiO2. In transmission electron microscopy the temperature range (i) is characterized by the appearance of “rod-like” defects and its transformation into dislocation loops, and the ranges (ii) and (iii) by the observation of platelet-shaped precipitates generating dislocation loops and stacking faults, leading to the conversion of the platelet-shaped precipitates into microprecipitates. Es wird die Präzipitation von Sauerstoff in versetzungsfreiem Czochralski-Silizium nach isothermaler Wärmebehandlung bei Temperaturen zwischen 400 und 1100 °C mit Hilfe der Infrarotspektroskopie und der Transmissions-Elektronenmikroskopie untersucht. Aus den Änderungen im Infrarotspektrum, die nach der Wärmebehandlung beobachtet werden, wird geschlossen, daß für niedrige Temperungstemperaturen (400 bis 750 °C) die Präzipitate aus amorphem SiOx (x < 2) bestehen, welches sich mit wachsender Temperatur in amorphes SiO2 umwandelt, daß bei mittleren Temperungstemperaturen (750 bis 950 °C) α-Cristobalit-Präzipitate gebildet werden, die sich bei hohen Temperungstemperaturen (950 bis 1100 °C) in amorphes SiO2 umwandeln. In der Transmissions-Elektronenmikroskopie wird der erste Temperaturbereich durch das Auftreten von „stäbchenförmigen”︁ Defekten und deren Umwandlung in Versetzungsschleifen charakterisiert und die beiden anderen Temperaturbereiche durch die Beobachtung von plättchenförmigen Präzipitaten, die Versetzungsschleifen und Stapelfehler erzeugen, was schließlich zu einer Umwandlung der plättchenförmigen Präzipitate in Mikropräzipitate führt.
Functions of Fibroblast Growth Factor Receptors in cancer defined by novel translocations and mutations (2015)

The four receptor tyrosine kinases (RTKs) within the family of Fibroblast Growth Factor Receptors (FGFRs) are critical for normal development but also play an enormous role in oncogenesis. Mutations and/or abnormal expression often lead to constitutive dimerization and kinase activation of FGFRs, and represent the primary mechanism for aberrant signaling. Sequencing of human tumors has revealed a plethora of somatic mutations in FGFRs that are frequently identical to germline mutations in developmental syndromes, and has also identified novel FGFR fusion proteins arising from chromosomal rearrangements that contribute to malignancy. This review details approximately 200 specific point mutations in FGFRs and 40 different fusion proteins created by translocations involving FGFRs that have been identified in human cancer. This review discusses the effects of these genetic alterations on downstream signaling cascades, and the challenge of drug resistance in cancer treatment with antagonists of FGFRs.
Sensor Deployment and Scheduling for Target Coverage Problem in Wireless Sensor Networks (2013)

Network lifetime plays an integral role in setting up an efficient wireless sensor network. The objective of this paper is twofold. The first one is to deploy sensor nodes at optimal locations such that the theoretically computed network lifetime is maximum. The second is to schedule these sensor nodes such that the network attains the maximum lifetime. Thus, the overall objective of this paper is to identify optimal deployment locations of the given sensor nodes with a pre-specified sensing range, and to schedule them such that the network lifetime is maximum with the required coverage level. Since the upper bound of the network lifetime for a given network can be computed mathematically, we use this knowledge to compute locations of deployment such that the network lifetime is maximum. Further, the nodes are scheduled to achieve this upper bound. In this paper, we use artificial bee colony algorithm and particle swarm optimization for sensor deployment problem followed by a heuristic for scheduling. A comparative study shows that artificial bee colony algorithm performs better for sensor deployment problem. The proposed heuristic was able to achieve the theoretical upper bound in all the experimented cases.
Photoreaction of benzoic acid with sodium hypochlorite in aqueous alkali (1984)

The photoreaction of benzoic acid with sodium hypochlorite in aqueous alkali (pH 12) has been studied. At a low initial ratio of [ClO–]/[PhCOO–], e.g. 0.1, hydroxylation and chlorination at the aromatic ring occur simultaneously with ipso-substitution of the carboxylate group to give hydroxy- and chloro-benzoic acids together with phenol. The product distribution depends on the wavelength of light, which implies the dependence on the concentration of active species generated from ClO– and on the light stability of products. At comparable concentrations of ClO– and PhCOO–, the products initially formed from the photoreaction react further with ClO– in the dark to give polychlorinated derivatives. The initial steps for the photoreaction are discussed on the basis of the reactivity of the active species, O(3P), O(1D), O–˙, and Cl·, generated by photolysis of ClO–.
The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor (1999)

The inv(16) is one of the most frequent chromosomal translocations associated with acute myeloid leukemia (AML). The inv(16) fusion protein acts by dominantly interfering with AML-1/core binding factor beta-dependent transcriptional regulation. Here we demonstrate that the inv(16) fusion protein cooperates with AML-1B to repress transcription. This cooperativity requires the ability of the translocation fusion protein to bind to AML-1B. Mutational analysis and cell fractionation experiments indicated that the inv(16) fusion protein acts in the nucleus and that repression occurs when the complex is bound to DNA. We also found that the inv(16) fusion protein binds to AML-1B when it is associated with the mSin3A corepressor. An AML-1B mutant that fails to bind mSin3A was impaired in cooperative repression, suggesting that the inv(16) fusion protein acts through mSin3 and possibly other corepressors. Finally, we demonstrate that the C-terminal portion of the inv(16) fusion protein contains a repression domain, suggesting a molecular mechanism for AML-1-mediated repression.
In Vitro Activity of Telavancin against Resistant Gram-Positive Bacteria (2008)

The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC(90), 0.5 to 1 microg/ml), streptococci (all MICs, < or =0.12 microg/ml), and VanB-type enterococci (all MICs, < or =2 microg/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.