gebhart/patrepeval huggingface dataset:
Interleukin-10 inhibits neutrophil phagocytic and bactericidal activity (1996)

Effective host defense against bacterial invasion is characterized by the vigorous recruitment and activation of inflammatory cells, which is dependent upon the coordinated expression of both pro- and anti-inflammatory cytokines. Interleukin-10 (IL-10) is a recently described cytokine with potent anti-inflammatory properties in vivo and in vitro. In this study we investigated whether IL-10 could directly regulate the ability of neutrophils (PMN) to phagocytose and kill bacteria. Initial studies demonstrated that human recombinant IL-10 (hrIL-10) inhibited the ability of PMN to phagocytose Escherichia coli in vitro. Inhibition of phagocytosis occurred in the absence of changes in CR1 (C3b) or Fc receptor expression, as treatment of PMN with IL-10 failed to induce significant changes in Fc gamma IIR, Fc gamma IIIR or CR1 cell surface expression. However, incubation of PMN with IL-10 resulted in a dose-dependent decrease in CDIIb (Mac-1) expression. In addition to effects on PMN phagocytosis, hrIL-10 significantly attenuated PMN microbicidal activity, as bactericidal assays revealed that co-incubation of PMN with hrIL-10 resulted in a marked decrease in killing of phagocytosed bacteria. Furthermore, IL-10 inhibited the production of superoxide from PMA-stimulated PMN, suggesting that the detrimental effects of IL-10 on PMN microbicidal activity were due, in part, to suppression of respiratory burst. In summary, our studies indicate that IL-10 inhibits PMN-dependent phagocytosis and killing of E. coli in vitro, and suggest that this cytokine may impair effective antibacterial host defense in vivo.
Efficient and robust regenerative all-optical wavelength converter for Cand L-band (80 nm span) and for data rates up to 40 Gbit/s (2000)

Summary form only given.Wavelength division multiplexed (WDM) networks will need optical wavelength converters in optical cross connects to avoid wavelength blocking when routing the signals. Interferometric devices have regenerative capabilities and are therefore of special interest to guarantee cascadibility. We present a monolithically integrated Mach-Zehnder interferometer with semiconductor optical amplifiers (MZI-SOA) that demonstrates efficient all-optical 2R regenerative 10 Gbit/s wavelength conversion over the full C- and L-band with a negative penalty of about -1 dB. The converted output signals have an optical signal-to-noise ratio (OSNR) better than 45 dB. All-optical 2R and 3R regenerative wavelength conversion at 40 Gbit/s within the entire C-band has been already reported using the same kind of device. We show that the device has the capability for regenerative wavelength conversion at 40 Gbit/s even in and beyond the L-band.
Ion Exchange of Phenylalanine in Fluidized/Expanded Beds (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIon Exchange of Phenylalanine in Fluidized/Expanded BedsJoon-Ho Koh, N.-H. Linda Wang, and Phillip C. WankatCite this: Ind. Eng. Chem. Res. 1995, 34, 8, 2700–2711Publication Date (Print):August 1, 1995Publication History Published online1 May 2002Published inissue 1 August 1995https://doi.org/10.1021/ie00047a020RIGHTS & PERMISSIONSArticle Views137Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Three-Coordinate Copper(I) Amido and Aminyl Radical Complexes (2009)

A three-coordinate Cu-NR(2) system (R = p-tolyl) supported by the anionic bis(phosphino)borate ligand [Ph(2)B(CH(2)P(t)Bu(2))(2)](-) has been isolated and structurally characterized in both its anionic Cu(I) and neutral (formally) Cu(II) oxidation states. A large rate constant for the self-exchange electron-transfer reaction (k(S) >or= 10(7) M(-1) s(-1)) makes this system a functional model for the type-1 active sites in blue copper proteins. Multiedge X-ray absorption spectroscopy, multifrequency electron paramagnetic resonance, and density functional theory analyses collectively indicate that the oxidized form is best regarded as a Cu(I)-aminyl radical complex rather than a Cu(II)-amido species, with about 70% localization of the unpaired electron on the NR(2) unit. Hydrogen-atom transfer and C-C coupling reactions are presented as examples of chemical reactivity manifested by this unusual electronic structure.
A Study On the Design of a Servo Controller for a Tracking Antenna System between Moving Vehicles by the Fuzzy-PID Controller (2005)

For continuous communication between moving vehicles such as satellites and unmanned aerial vehicles, an antenna system having at least more than 2-axes is needed. When the antenna is mounted on a moving vehicle such as ground vehicle, ship and so on, a stabilization and tracking system must be equipped to compensate the roll, pitch and yaw motion of the vehicle. The performance of stabilization and tracking system mainly depends on the servo control system that driving the antenna pedestal. Therefore, in this paper, a Fuzzy-PID controller for a stabilization and tracking system of a 2-axes antenna was designed and the performance was verified. To verify the verification of designed servo control system, the performance of the conventional PID controller and that of the Fuzzy-PID controller, designed by the same PID control gains, was compared.
Modified multilevel layout optimization method of composite wing structure (2013)

A three level layout optimization strategy is proposed in this paper for large-scale composite wing structures. Design requirements are adjusted at the primary level according to structural deformation and strength, then the stringers and ribs layout are designed by the instability criteria at the second level, at last the laminate optimization is used to increase the composite panel carrying efficiency. In this paper, stiffened wing panels first are modeled by the equivalent laminate plates, whose thickness is determined by the global wing structure's deformation and strength. At last a detailed FEM model is build to reflect accurate instability limit and is used to do global synthetical optimization. Finally, the three level optimization of large-scale wing structure is completed as an example. The result fulfills design requirements and shows the feasibility of this method.
The Origin of the Constant Carbohydrate Diet (2009)

The Constant Carbohydrate diet, based entirely on carbohydrate exchanges, is now widely used in the dietary treatment of diabetes mellitus. Being based on sound scientific principles and simple in design, the Constant Carabohydrate diet is appropriate for all those having diabetes mellitus, young or old, no matter their ethncity. This report describes why and how it was developed in 1951. Its simplicity makes it adaptable to all ethnic diets.
Efficient electropulse transformation of intact <i>Candida maltosa</i> cells by different homologous vector plusmids (1992)

Conditions for efficient and quick transformation by electroporation were developed in Candida maltosa. To investigate the efficiency of transformation with integrative as well as with autonomously replicating plasmids, a series of vectors was constructed for homologous transformation of this species. Transformants were obtained with different plasmids as covalently closed circular molecules and as linearized DNA. The influence of recipient strain and plasmid type as well as of cell number and parameters of the supplied electrical pulse on the transformation efficiency have been investigated. A maximum of 7000 transformants per 100 ng of plasmid DNA was reached. The efficiency of transformation was compared with that of the LiCl method.
High-speed liquid-crystal optical deflector for 3D display (2009)

Liquid-crystal (LC) varifocal lens or LC optical deflector is useful for 3-D display. In this paper, we propose a highspeed optical deflector for 3-D display using a new LC motion. This device responds at double frequency of an applied voltage when high voltage is applied. The voltage, position and time dependences of deflection angle using square-wave or sine-wave voltage are described in this paper.
Endothelial Von Willebrand Factor Promotes Blood–Brain Barrier Flexibility and Provides Protection From Hypoxia and Seizures in Mice (2013)

VWF deficiency confers partial preservation of BBB integrity after hypoxia/reoxygenation and seizures. Surprisingly, this decrease in BBB permeability did not result in protection of animals because they demonstrated more severe pathology in both models compared with wild-type animals. These data suggest that a rigid BBB is detrimental (to the organism) during certain disease states and that VWF release may provide desired flexibility under stress.
Utility of recycled bedding for laboratory rodents. (2009)

Animal facilities generate a large amount of used bedding containing excrement as medical waste. We developed a recycling system for used bedding that involves soft hydrothermal processing. In this study, we examined the effects of bedding type on growth, hematologic and serum biochemical values, and organ weights of female and male mice reared on either recycled or fresh bedding from 3 to 33 wk of age. Neither growth nor physiology differed between mice housed on recycled bedding compared with fresh bedding. When 14-wk-old mice were bred, litter size and total number of weaned pups showed no significant differences between animals raised on recycled or fresh bedding. Because bedding type influences the environment within cages and animal rooms, we evaluated particulate and ammonia data from cages and animal rooms. Values were significantly lower from cages and rooms that used recycled bedding than from those using fresh bedding, thus indicating that recycled bedding has the potential to improve the environment within both cages and animal rooms. Overall, this study revealed that recycled bedding is an excellent material for use in housing laboratory rodents. Specifically, recycled bedding may reduce medical waste and maintain healthy environments within cages and animal rooms.
Colloids make ultrafast optical devices (1997)

A Group at the University of Pittsburgh in the US has created a new class of materials that could herald another generation of devices for optical communications and computing. Sanford Asher and colleagues combined polymer chemistry with the unique properties of colloids to make three-dimensional gratings with striking optical properties. Beams of light can switch the diffractive properties of the gratings on and off, transforming the material in nanoseconds from a glass-like transparency to an iridescence similar to that observed in opals (G Pan et al. 1997 Phys. Rev. Lett.20 3860).
Parallel Data Vault Methods for Larger Scale Stochastic Dynamic Programming (1992)

The decomposition of the finite difference approximation to stochastic dynamic programming problems is described for the optimal control of nonlinear, continuous time dynamical systems. The stochastic components include both Gaussian and Poisson random white noise. A parallel data vault mass storage method is developed to take advantage of the decomposition, and therefore to help alleviate Bellman's curse of dimensionality in dynamic programming computations. It is shown that data vault memory on the data parallel Connection Machine type computational model can be enhance the efficiency of the decomposition performance. Extension of the data vault technique to a more general stochastic optimal control problem is discussed. Performance on the Connection Machine for larger scale stochastic dynamic programming problems, such as resource management problems with up to a projected six states, are illustrated and discussed.
Beyond NomBank: A Study of Implicit Arguments for Nominal Predicates (2010)

Despite its substantial coverage, Nom-Bank does not account for all withinsentence arguments and ignores extrasentential arguments altogether. These arguments, which we call implicit, are important to semantic processing, and their recovery could potentially benefit many NLP applications. We present a study of implicit arguments for a select group of frequent nominal predicates. We show that implicit arguments are pervasive for these predicates, adding 65 % to the coverage of NomBank. We demonstrate the feasibility of recovering implicit arguments with a supervised classification model. Our results and analyses provide a baseline for future work on this emerging task. 1
Functional neural differentiation of human adipose tissue-derived stem cells using bFGF and forskolin (2010)

These combined results indicate that hADSCs have the same self-renewing capacity and multipotency as stem cells, and can be differentiated into functional neurons using bFGF and forskolin.
Construction of Chromosome Jumping and Linking Libraries in <i>E. coli</i> (1994)

Chromosome jumping allows the use of one point on a chromosome as a starting point for exploring another potentially distant point on the same chromosome without cloning the intervening sequences as in chromosome walking. A linking library consists of genomic fragments that each contain a particular restriction site with a marker inserted into it. Because the sequences flanking the marker represent the termini of two contiguous genomic restriction fragments, the linking clones can be used, in conjunction with a specific jumping library made with the same restriction enzyme, to expedite jumping between consecutive restriction fragments. Separate protocols present strategies for constructing general and specific jumping libraries from total genomic DNA. An additional protocol details construction of a linking library from flow-sorted chromosomes. Support protocols provide instructions for preparing genomic insert DNA, supF gene fragments, and Chromosome jumping allows the use of one point on a chromosome as a starting point for exploring another potentially distant.
Synthesis and Antifertility Activity of 1,5-Diaryl-3-(3'-indolyl)formazans are described. (1994)

The synthesis and antifertility activity of 1, 5-diaryl-3-(3'-indolyl)formazans with a substituted aryl group (2-8) are described.
Soft Tissue Defect of Posterior Neck and Scalp after Reconstruction with Lower Trapezius Myocutaneous Flap for Seven Years: A Case Report (2005)

A 45-year-old male who has been suffered from diabetes mellitus for about twenty years was admitted to our hospital. Two weeks before admission, several carbuncles with abscess formation were noted on the posterior neck and scalp. After debridement, a large skin and soft tissue defect of about 20×10×2 cm was noted. We successfully used the lower trapezius myocutaneous flap to cover such a large soft tissue defect seven years ago. The recent follow up study of the patient showed good coverage of the previous skin and soft tissue defect and good functional recovery of the posterior neck without impairing shoulder function.
Interworking among intelligent networks and different networks: service control interfaces and their applications (2002)

A service control interface is proposed that can be used for telephony services provided by interworking among intelligent networks (INs), computer telephony (CT), and voice over IP (VoIP) systems. The IN Application Protocol (INAP) is mapped to a CORBA (Common Object Request Broker Architecture) interface, based on a proposed rule that achieves lightweight implementation. The proposed interface was implemented and confirmed by several service examples running on experimental systems.
Description of the Superdeformed Bands of Odd-Odd Nuclei in <i>A</i> ∼ 80 Region (2005)

Properties of the superdeformed bands of odd-odd nuclei in A ∼ 80 mass region are investigated systematically within the supersymmetry scheme including many-body interactions and a perturbation possessing the SO(5) (or SU(5)) symmetry on the rotational symmetry. The obtained γ-ray energies, and the dynamical moments of inertia agree with experimental data. It shows that this approach is quite powerful in describing odd-odd nuclei in A ∼ 80 mass region.
Characterization of deadenylation in trypanosome extracts and its inhibition by poly(A)-binding protein Pab1p (2004)

The stability of mRNAs is an important point in the regulation of gene expression in eukaryotes. The mRNA turnover pathways have been identified in yeast and mammals. However, mRNA turnover pathways in trypanosomes have not been widely studied. Deadenylation is the first step in the major mRNA turnover pathways of yeast and mammals. To better understand mRNA degradation processes in these organisms, we have developed an in vitro mRNA turnover system that is functional for deadenylation. In this system, addition of poly(A) homopolymer activates the deadenylation of poly(A) tails. The trypanosomal deadenylase activity is a 3'-->5' exonuclease specific for adenylate residues, generates 5'-AMP as a product, is magnesium dependent, and is inhibited by neomycin B sulfate. These characteristics suggest similarity with other eukaryotic deadenylases. Furthermore, this activity is cap independent, indicating a potential difference between the trypanosomal activity and PARN, but suggesting similarity to Ccr4p/Pop2p activities. Extracts immunodepleted of Pab1p required the addition of poly(A) competition to activate deadenylation. Trypanosomal Pab1p functions as an inhibitor of the activity under in vitro conditions. Pab1p appears to be one of several mRNA stability proteins in trypanosomal extracts.
Broadcast news parsing using visual cues: a robust face detection approach (2002)

Automatic content-based analysis and indexing of broadcast news recordings or digitized news archives is becoming an important tool in the framework of many multimedia interactive services such as news summarization, browsing, retrieval and news-on-demand (NoD) applications. Existing approaches have achieved high performance in such applications but heavily rely on textual cues such as closed caption tokens and teletext transcripts. We present an efficient technique for temporal segmentation and parsing of news recordings based on visual cues that can either be employed as a stand-alone application for non-closed captioned broadcasts or integrated with audio and textual cues of existing systems. The technique involves robust face detection by means of color segmentation, skin color matching and shape processing, and is able to identify typical news instances like anchor persons, reports and outdoor shots.
UV, Blue, Green, Yellow, Red, and Small: Newest Developments on Eu<sup>2+</sup>-Doped Nanophosphors (2015)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTUV, Blue, Green, Yellow, Red, and Small: Newest Developments on Eu2+-Doped NanophosphorsHuayna Terraschke and Claudia Wickleder*View Author Information Inorganic Chemistry, Science and Technology Faculty, University of Siegen, Adolf-Reichwein-Strasse 2, 57068 Siegen, Germany*E-mail: [email protected]Cite this: Chem. Rev. 2015, 115, 20, 11352–11378Publication Date (Web):September 23, 2015Publication History Received14 April 2015Published online23 September 2015Published inissue 28 October 2015https://pubs.acs.org/doi/10.1021/acs.chemrev.5b00223https://doi.org/10.1021/acs.chemrev.5b00223review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views7379Altmetric-Citations262LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Europium,Ions,Nanomaterials,Nanoparticles,Phosphors Get e-Alerts
SOS factors involved in translesion synthesis (1997)

Mutations are permanent DNA sequence changes that can be induced when replication occurs on a damaged DNA template. In Escherichia coli, the process of translesion synthesis past a lesion that hinders replication requires the induction of SOS-controlled gene products, among which are those of the umuDC operon. To study translesion synthesis in vivo, we have constructed single-stranded vectors containing single 2-acetylaminofluorene adducts located within -1 and -2 frameshift mutation hot spots formed by short repetitive sequences. These adducts strongly hinder DNA replication as only 2-5% of the molecules give rise to progeny under non-SOS-induced conditions. Induction of the SOS response lead to a 10-fold increase in survival. Adducts present within repetitive sequences trigger the formation of misaligned primer/template replication intermediates which, upon elongation, will result in the fixation of frameshift errors (mutagenic translesion synthesis). Surprisingly we find that elongation from the nonslipped intermediate depends upon functional umuDC+ gene products, whereas elongation from the slipped intermediate is umuDC+ independent but requires another, as yet biochemically uncharacterized, SOS function. These data are discussed in terms of the different steps involved during translesion synthesis through a replication-blocking lesion.
Honey in the treatment of burns: a systematic review and meta-analysis of its efficacy. (2009)

Available evidence indicates markedly greater efficacy of honey compared with alternative dressing treatments for superficial or partial thickness burns, although the limitations of the studies included in the meta-analysis restrict the clinical application of these findings. Further studies are urgently required to determine the role of honey in the management of superficial or partial thickness burns.