gebhart/patrepeval huggingface dataset:
Tracking by an Optimal Sequence of Linear Predictors (2009)

We propose a learning approach to tracking explicitly minimizing the computational complexity of the tracking process subject to user-defined probability of failure (loss-of-lock) and precision. The tracker is formed by a Number of Sequences of Learned Linear Predictors (NoSLLiP). Robustness of NoSLLiP is achieved by modeling the object as a collection of local motion predictors--object motion is estimated by the outlier-tolerant RANSAC algorithm from local predictions. Efficiency of the NoSLLiP tracker stems from (i) the simplicity of the local predictors and (ii) from the fact that all design decisions--the number of local predictors used by the tracker, their computational complexity (i.e. the number of observations the prediction is based on), locations as well as the number of RANSAC iterations are all subject to the optimization (learning) process. All time-consuming operations are performed during the learning stage--tracking is reduced to only a few hundreds integer multiplications in each step. On PC with 1xK8 3200+, a predictor evaluation requires about 30 microseconds. The proposed approach is verified on publicly-available sequences with approximately 12000 frames with ground-truth. Experiments demonstrates, superiority in frame rates and robustness with respect to the SIFT detector, Lucas-Kanade tracker and other trackers.
Image guidance: fluoroscopic navigation. (2004)

Computer-assisted orthopaedic surgery slowly is making its way into routine orthopaedic practice. Orthopaedic trauma has long been identified as a potential impact area of this new technology. Early experience with three-dimensional (3D) image-guided surgery was promising, but this particular technique was limited by the inability to update the 3D computer model in the operating room after fracture reduction maneuvers or implant placement. Virtual fluoroscopy, or fluoroscopic navigation, became available in 1999 and has proven to be a more versatile technology for fracture treatment. Fluoroscopic navigation systems allow the surgeon to store multiple intraoperative fluoroscopic images on a computer workstation; the position of special optically-tracked surgical instruments or implants then may be virtually overlaid onto the stored images in multiple planes during implant placement. The ability to update images after fracture manipulation now has expanded the application of computer-assisted surgery to any procedures that traditionally have relied on intraoperative C-arm use. In selected applications, this technology has been shown to decrease operative time and intraoperative radiation exposure. The advantages of the new technique of fluoroscopic navigation and its current use in trauma applications will be discussed.
A Microlysimeter Field Study of Solute Transport through a Structured Sandy Loam Soil (1986)

Abstract A 49‐d field experiment monitoring water and solute movement through a structured sandy loam is reported. Two field plots, each 15 by 30 m 2 in area were instrumented with a 3 by 6 grid of small lysimeters containing undisturbed soil. Each lysimeter was weighed before and after irrigation and had effluent concentrations and drainage volumes recovered periodically. At the beginning of the experiment a pulse of KBr was added to the field and lysimeters with a mechanical lawn spreader and was leached into the soil with three water irrigations per week. Each plot received the same amount of water per irrigation but at intensities of 5.5 and 9.5 mm/h. Effluent breakthrough curves were constructed for each lysimeter. Substantial indication of preferential flow through part of the wetted pore space was observed in each lysimeter and the average breakthrough curves reflected substantial bypass. A statistical analysis of the drainage concentrations as a function of time showed the two fieldwide breakthrough curves to be identical. This not only showed that no intensity effect was apparent for solute movement on these plots but also indicated that the plot areas were large enough to incorporate all of the field scale variability within them. A calculation of solute flux from each lysimeter showed no correlation between instantaneous drainage and instantaneous solute concentration. As a consequence, we were able to show that the traditional method of estimating field scale solute flux as the product of average drainage and average concentration was adequate to describe solute leaching below the fields. Thirty‐six soil cores were taken in the two plots at the conclusion of the experiment. The average concentration depth patterns were similar for the two treatments and showed evidence of movement to at least 1.2 m during the lifetime of the experiment, implying that preferential flow continued to occur to greater depths.
Structural Characterization of the Lipid A Component of Sinorhizobium sp. NGR234 Rough and Smooth Form Lipopolysaccharide (2003)

A broad-host-range endosymbiont, Sinorhizobium sp. NGR234 is a component of several legume-symbiont model systems; however, there is little structural information on the cell surface glycoconjugates. NGR234 cells in free-living culture produce a major rough lipopolysaccharide (LPS, lacking O-chain) and a minor smooth LPS (containing O-chain), and the structure of the lipid A components was investigated by chemical analyses, mass spectrometry, and NMR spectroscopy of the underivatized lipids A. The lipid A from rough LPS is heterogeneous and consists of six major bisphosphorylated species that differ in acylation. Pentaacyl species (52%) are acylated at positions 2, 3, 2', and 3', and tetraacyl species (46%) lack an acyl group at C-3 of the proximal glucosamine. In contrast to Rhizobium etli and Rhizobium leguminosarum, the NGR234 lipid A contains a bisphosphorylated beta-(1' --> 6)-glucosamine disaccharide, typical of enterobacterial lipid A. However, NGR234 lipid A retains the unusual acylation pattern of R. etli lipid A, including the presence of a distal, amide-linked acyloxyacyl residue containing a long chain fatty acid (LCFA) (e.g. 29-hydroxytriacontanoate) attached as the secondary fatty acid. As in R. etli, a 4-carbon fatty acid, beta-hydroxybutyrate, is esterified to (omega - 1) of the LCFA forming an acyloxyacyl residue at that location. The NGR234 lipid A lacks all other ester-linked acyloxyacyl residues and shows extensive heterogeneity of the amide-linked fatty acids. The N-acyl heterogeneity, including unsaturation, is localized mainly to the proximal glucosamine. The lipid A from smooth LPS contains unique triacyl species (20%) that lack ester-linked fatty acids but retain bisphosphorylation and the LCFA-acyloxyacyl moiety. The unusual structural features shared with R. etli/R. leguminosarum lipid A may be essential for symbiosis.
Particle Size and Shape Effects in Materials Science: Examples from Polymer and Paper Systems (1993)

Abstract Large quantities of clay minerals (and other micron-sized mineral powders) are used widely in materials science. Mineral fillers are major components, for example, of paints, rubber, plastics and paper and board. While the original object of such incorporation was to reduce costs, performance is now being “engineered” by design or choice of the relevant mineral particles. This paper concentrates on the use of mineral powders in polymer and paper science. In both application areas, the size and shape of the mineral particles can affect mechanical properties such as stiffness and tensile and impact strength. However, other characteristics are also modified. For example, the drainage rate in paper formation and the rheology of a polymer melt, properties which are critically important to the rate of processing of the relevant materials, can be greatly affected. Finally, the size and shape of the mineral particles also affect appearance, i.e. the smoothness, uniformity, optical properties etc. Mechanical and rheological data are presented for mineral-filled polypropylene, as are mechanical and optical data for filled and coated paper.
Non‐invasive methods for determination of oedema and water behaviour in the skin (1995)

The behaviour of water in normal young and aged skin has been characterised with magnetic resonance and ultrasonography. Little is yet known about water distribution and behaviour in skin oedema characteristic e.g. for the post-thrombotic syndrome and lymphoedema. Further research in this field is likely to be carried out in the future.
Inhibitory Effects of Magnoshinin and Magnosalin, Compounds from “Shin-i” (Flos Magnoliae), on the Competence and Progression Phases in Proliferation of Subcultured Rat Aortic Endothelial Cells (1992)

Anti-proliferative effects of magnoshinin and magnosalin derived from “Shin-i” (Flos magnoliae) were investigated using subcultured endothelial cells (EC) of rat aorta. The inhibitory effects of magnoshinin were 2-fold greater at 10 μg/ml than that of magnosalin on the increase in cell number when EC were stimulated by 5% fetal bovine serum. In the 3H-thymidine incorporation monitored at 3 hr-intervals, magnoshinin (0.1–3 μg/ml) prolonged the starting time of DNA synthesis and reduced the rate of incorporation into EC. Magnosalin (0.3–3 μg/ml) reduced only the incorporation rate. These results suggest that magnoshinin inhibits both the competence phase and progression phase, but magnosalin preferentially inhibits the progression phase in EC proliferation.
Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993). (1999)

Seventeen Indian hepatitis E virus (HEV) isolates, representing epidemic and sporadic hepatitis E cases during 1976-1991, were sequenced in the RNA polymerase (RNAP) region. Five isolates were also sequenced in the non-structural hypervariable region of open reading frame 1. Open reading frames 2 and 3 were sequenced only for the prototype isolate. On the basis of the comparison of all the available sequences of the conserved RNAP region, the HEV isolates were divided into three genotypes, differing from each other by >15%. Genotype I included African and Asian isolates, whereas II and III were represented by Mexican and US isolates, respectively. Genotype I was further divided into four sub-genotypes. The majority of the Indian isolates (15/20), along with the Burmese and Nepali isolates, belonged to genotype IA. Genotype IB included HEV isolates from China, Pakistan and the former USSR and 2/20 Indian isolates, which represented the oldest (1976) HEV sequenced so far. Genotype IC included both the African isolates, whereas 3/20 Indian isolates formed genotype ID. Nucleotide sequence analysis of other regions of the HEV genome also placed isolates in the same genotypes. Both the Indian cities experiencing second HEV epidemics, after intervals of 8 and 10 years, showed shifts in the sub-genotypes found; from IB (Ahm-76) to IA (Ahm-84) and from IA (Kol-81) to ID (Kol-91). However, no major shift in the genotypes was noted. Overall, HEV genotypes appear to be segregated geographically.
Haemostatic function in myocardial infarction. (1986)

Coagulation factor VIII, von Willebrand factor, antithrombin, fibrinogen, plasminogen activator capacity, and inhibitors of fibrinolysis, including a recently discovered fast inhibitor of tissue plasminogen activator, were measured three to six months after myocardial infarction in 116 male and 32 female patients aged less than 45 and in 136 age and sex matched random controls. Plasma concentrations of fibrinogen and the fast inhibitor of tissue plasminogen activator were raised in male patients (with or without correction for orosomucoid levels, blood group distribution, tobacco and alcohol consumption, and weight/height index) and plasminogen activator capacity was reduced. In female patients the concentrations of factor VIII, von Willebrand factor, the fast inhibitor of tissue plasminogen activator, alpha 2-antiplasmin, and C1 inhibitor were significantly increased. The increase in factor VIII concentrations depended strongly on a persisting inflammatory response. Multivariate analysis indicated that a combination of fibrinogen and tissue plasminogen activator inhibitor concentrations gave the best independent discrimination between male patients and controls. For female patients the best combination was von Willebrand factor and tissue plasminogen activator inhibitor. Male patients with multiple vessel atheromatosis at coronary angiography had higher fibrinogen concentrations than those with atheromatosis of a single vessel. Atheromatosis was defined as sharp-edged, plaque-like, or irregular indentations, often multiple, into the vessel lumen without features suggesting fibromuscular hyperplasia.
Foot-and-mouth disease virus particles contain replicase protein 3D. (1994)

An antibody against the Escherichia coli-expressed RNA polymerase of foot-and-mouth disease virus (FMDV) reacts with the virus in ELISA and radioimmunoprecipitation experiments and with a protein of the disrupted virus particle in an immunoblot analysis. Treatment of the virus with trypsin, which cleaves capsid protein VP1 and a 56-kDa polypeptide present in trace amount in the particles, reduces the level of the reaction in ELISA and radioimmunoprecipitation and eliminates the immunoblot reaction. Electron microscopy showed that only approximately 20% of the virus particles reacted with the anti-polymerase antibody, whereas most reacted with an antibody against the immunodominant G-H loop of the virus. In the presence of ammonium ions, the expressed polymerase degrades the RNA of the virus into molecules sedimenting at approximately 12 S, indicating that it can act as a hydrolytic as well as a polymerizing enzyme. Moreover, the RNA in trypsin-treated virus particles is degraded when incubated at 37 degrees C, suggesting that the cleaved 56-kDa protein still possesses hydrolytic activity. In addition, the anti-polymerase antibody, which inhibits the polymerase activity of the E. coli-expressed protein, also partially inhibits the hydrolytic activity of the previously described endonuclease of the virus particle, suggesting that this enzyme is identical with the polymerase or forms part of it.
Efficacy of End-Only-Functionalized Oligo(arylene-ethynylene)s in Killing Bacterial Biofilms (2012)

Cationic end-only-functionalized oligo(arylene-ethynylene)s (EO-OPEs) have recently been found to be broad-spectrum and effective antimicrobial agents because of their unique structure and optical properties. In this study, we investigated their potential use for preventing and reducing Escherichia coli (E. coli) biofilms. The Calgary biofilm device (CBD) was used to form bacterial biofilms of E. coli; in these studies, the minimum inhibitory concentration (MIC) and the minimum biofilm eradication concentration (MBEC) were determined. E. coli biofilms uniformly grow on pegs of the CBD device lid. The MIC values determined for EO-OPEs are comparable to those found for standard antibiotics such as kanamycin (MIC = 11.2 μg/mL). About 10-30 times the concentration of EO-OPEs was required to eradicate E. coli biofilms and prevent regrowth in the dark. Near-UV irradiation of EO-OPEs enhanced their efficacy in killing biofilms.
A practical approach to processing flexible displays (2010)

Abstract— The materials and fabrication aspects of flexible displays will be reviewed. The fabrication of flexible displays requires the consideration of proper material selection, handling of plastic‐film substrates, and a low‐temperature process for the fabrication of active‐matrix devices on plastic substrate. In addition, for the low‐cost fabrication approach, direct printing of active‐matrix patterning without a photolithography process is also required. Before commercial‐level production of flexible displays is considered, the factors of product reliability and practical value are considered. Samsung LCD Division's approach to the fabrication of flexible displays and future plans to develop a practical method that will lead to the production level of flexible displays will also be described.
Isolation of a Paenibacillus sp. Strain and Structural Elucidation of Its Broad-Spectrum Lipopeptide Antibiotic (2012)

This research was initiated to search for novel antimicrobial compounds produced by food or environmental microorganisms. A new bacterial strain, designated OSY-SE, which produces a unique and potent antimicrobial agent was isolated from soil. The isolate was identified as a Paenibacillus sp. through cultural, biochemical, and genetic analyses. An antimicrobial compound was extracted from Paenibacillus OSY-SE with acetonitrile and purified using liquid chromatography. After analyses by mass spectrometry (MS) and nuclear magnetic resonance (NMR), the antimicrobial compound was determined to be a cyclic lipopeptide consisting of a C(15) fatty acyl (FA) chain and 13 amino acids. The deduced sequence is FA-Orn-Val-Thr-Orn-Ser-Val-Lys-Ser-Ile-Pro-Val-Lys-Ile. The carboxyl-terminal Ile is connected to Thr by ester linkage. The new compound, designated paenibacterin, showed antagonistic activities against most Gram-positive and Gram-negative bacteria tested, including Listeria monocytogenes, methicillin-resistant Staphylococcus aureus, Escherichia coli O157:H7, and Salmonella enterica serovar Typhimurium. Paenibacterin is resistant to trypsin, lipase, α-glucosidase, and lysozyme. Its antimicrobial activity was lost after digestion by pronase and polymyxin acylase. Paenibacterin is readily soluble in water and fairly stable to exposure to heat and a wide range of pH values. The new isolate and its antimicrobial agent are being investigated for usefulness in food and medical applications.
Topological Hunds rules and the electronic properties of a triple lateral quantum dot molecule (2007)

We analyze theoretically and experimentally the electronic structure and charging diagram of three coupled lateral quantum dots filled with electrons. Using the Hubbard model and real-space exact diagonalization techniques we show that the electronic properties of this artificial molecule can be understood using a set of topological Hunds rules. These rules relate the multielectron energy levels to spin and the interdot tunneling $t$, and control charging energies. We map out the charging diagram for up to $N=6$ electrons and predict a spin-polarized phase for two holes. The theoretical charging diagram is compared with the measured charging diagram of the gated triple-dot device.
Recombinant Protein-<i>co</i>-PEG Networks as Cell-Adhesive and Proteolytically Degradable Hydrogel Matrixes. Part II:  Biofunctional Characteristics (2006)

We present here the biological performance in supporting tissue regeneration of hybrid hydrogels consisting of genetically engineered protein polymers that carry specific features of the natural extracellular matrix, cross-linked with reactive poly(ethylene glycol) (PEG). Specifically, the protein polymers contain the cell adhesion motif RGD, which mediates integrin receptor binding, and degradation sites for plasmin and matrix-metalloproteinases, both being proteases implicated in natural matrix remodeling. Biochemical assays as well as in vitro cell culture experiments confirmed the ability of these protein-PEG hydrogels to promote specific cellular adhesion and to exhibit degradability by the target enzymes. Cell culture experiments demonstrated that proteolytic sensitivity and suitable mechanical properties were critical for three-dimensional cell migration inside these synthetic matrixes. In vivo, protein-PEG matrixes were tested as a carrier of bone morphogenetic protein (rhBMP-2) to heal critical-sized defects in a rat calvarial defect model. The results underscore the importance of fine-tuning material properties of provisional therapeutic matrixes to induce cellular responses conducive to tissue repair. In particular, a lack of rhBMP or insufficient degradability of the protein-PEG matrix prevented healing of bone defects or remodeling and replacement of the artificial matrix. This work confirms the feasibility of attaining desired biological responses in vivo by engineering material properties through the design of single components at the molecular level. The combination of polymer science and recombinant DNA technology emerges as a powerful tool for the development of novel biomaterials.
CoDrive: Improving Automobile Positioning via Collaborative Driving (2018)

An increasing number of depth sensors and surrounding-aware cameras are being installed in the new generation of cars. For example, Tesla Motors uses a forward radar, a front-facing camera, and multiple ultrasonic sensors to enable its Autopilot feature. Meanwhile, older or legacy cars are expected to be around in volumes, for at least the next 10 to 15 years. Legacy car drivers rely on traditional GPS for navigation services, whose accuracy varies 5 to 10 meters in a clear line-of-sight and degrades up to 30 meters in a downtown environment. At the same time, a sensor-rich car achieves better accuracy due to high-end sensing capabilities. To bridge this gap, we propose CoDrive, a system to provide a sensor-rich car's accuracy to a legacy car. We achieve this by correcting GPS errors of a legacy car on an opportunistic encounter with a sensor-rich car. CoDrive uses smartphone GPS of all participating cars, RGB-D sensors of sensor-rich cars, and road boundaries of a traffic scene to generate optimization constraints. Our algorithm collectively reduces GPS errors, resulting in accurate reconstruction of a traffic scene's aerial view. CoDrive does not require stationary landmarks or 3D maps. We empirically evaluate CoDrive which is shown to achieve a 90% and a 30% reduction in cumulative GPS error for legacy and sensor-rich cars respectively, while preserving the shape of the traffic.
Quantitative Analysis of Phospholipids Using Nanostructured Laser Desorption Ionization Targets (2011)

Since its introduction as an ionization technique in mass spectrometry, matrix-assisted laser desorption ionization (MALDI) has been applied to a wide range of applications. Quantitative small molecule analysis by MALDI, however, is limited due to the presence of intense signals from the matrix coupled with non-homogeneous surfaces. The surface used in nano-structured laser desorption ionization (NALDI) eliminates the need for a matrix and the resulting interferences, and allows for quantitative analysis of small molecules. This study was designed to analyze and quantitate phospholipid components of liposomes. Here we have developed an assay to quantitate the DPPC and DC(8,9)PC in liposomes by NALDI following various treatments. To test our method we chose to analyze a liposome system composed of DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) and DC(8,9)PC (1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine), as DC(8,9)PC is known to undergo cross-linking upon treatment with UV (254 nm) and this reaction converts the monomer into a polymer. First, calibration curves for pure lipids (DPPC and DC(8,9)PC) were created using DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) as an internal standard. The calibration curve for both DPPC and DC(8,9)PC showed an R(2) of 0.992, obtained using the intensity ratio of analyte and internal standard. Next, DPPC:DC(8,9)PC liposomes were treated with UV radiation (254 nm). Following this treatment, lipids were extracted from the liposomes and analyzed. The analysis of the lipids before and after UV exposure confirmed a decrease in the signal of DC(8,9)PC of about 90%. In contrast, there was no reduction in DPPC signal.