gebhart/patrepeval huggingface dataset:
Advanced Current Sensing Techniques for Power Electronic Converters (2007)

Current sensing is widely used in power electronic applications including dc-dc power conversion and adjustable speed motor drives, which are the basic subsystems of hybrid vehicles. Dynamic performance and control of the system depend on the accuracy and efficiency of its sensors. Several current sensing methods are reviewed and examined in this paper. Conventional methods including current sensing resistor technique as well as advanced self-tuning and self-calibrating approaches are described. Various methods are analyzed and compared based on their losslessness, simplicity, and ease of implementation. High-power applications are also considered.
EYESIGHT IN INDUSTRY (1942)

<h3>PRIME IMPORTANCE OF EYESIGHT IN INDUSTRY</h3> Industrial efficiency depends on good vision. The employer who is concerned with the welfare and health of his employees reaps a tangible reward in work well done. The employee, likewise, gains for himself a knowledge of his capacity and proper care of his disabilities. The correction of defective vision, the maintenance of lighting conditions appropriate to the work performed and the protection of the eyes in hazardous occupations, all these are necessarily of concern to industrial managements. The purpose of this article is to acquaint those persons who are interested with the many phases of vision and the factors concerning the eye of the employee from the standpoint of the eye physician and surgeon, the ophthalmologist. So far as I have been able to discover, no comprehensive and thorough contribution of this nature has ever been written. It is, however, true that a survey
A scalable approach to user-session based testing of web applications through concept analysis (2004)

The continuous use of the Web for daily operations by businesses, consumers, and government has created a great demand for reliable Web applications. One promising approach to testing the functionality of Web applications leverages user-session data collected by Web servers. This approach automatically generates test cases based on real user profiles. The key contribution of This work is the application of concept analysis for clustering user sessions for test suite reduction. Existing incremental concept analysis algorithms can be exploited to avoid collecting large user-session data sets and thus provide scalability. We have completely automated the process from user session collection and reduction through replay. Our incremental test suite update algorithm coupled with our experimental study indicate that concept analysis provides a promising means for incrementally updating reduced test suites in response to newly captured user sessions with some loss in fault detection capability and practically no coverage loss.
A novel design of behavioral analysis capability in mobile SNS (2009)

This paper introduces a novel design of the behavioral analysis capability in mobile SNS. The capability has a basic part comprises relationship based interface, content based interface and time based interface. The basic capability can either provide APIs directly up to applications or encapsulate into advanced capability with the core of relationship based interface. Afterwards, explaining the usability of this capability through its disposition in mobile SNS. Finally, by using basic and advanced interfaces respectively, two typical application examples represent the practicability of behavioral analysis capability.
GPS tracking of freight vehicles to identify and classify bottlenecks (2012)

This paper presents a systematic methodology for identifying and ranking bottlenecks using probe data collected by commercial GPS fleet management devices. This methodology is based on the hypotheses that truck speed distributions can be represented by either a unimodal or bimodal probability density function, and it proposes a new reliability measure for evaluating roadway performance.
Conscious sedation in a specialty hospital. (1994)

1. The patient under i.v. conscious sedation retains the ability to independently maintain a patent airway and respond appropriately to verbal commands and physical stimulation. He or she also has a depressed level of consciousness, and decreased pain and anxiety. 2. For a nurse to administer conscious sedation, conscious sedation policies, procedures and protocols must be in place within the institution. 3. Patients receiving conscious sedation must be monitored for physical changes in blood pressure, cardiac rate and rhythm, oxygen saturation, skin condition, pain, emotional status, and cognitive ability.
1-kW high-quality beam generation from a diode-side-pumped Nd:YAG rod laser (2002)

We demonstrated a power scaling of Nd: YAG rod laser by cascaded-coupling of two identical bifocusing compensation resonators. The maximum output power of 1030 W was achieved with the beam quality of M2 = 9. The corresponding electrical-to- optical efficiency was 23 %.
Effect of background colour on growth and adhesion strength of<i>Ulva</i>sporelings (2008)

This study examined the effects of a range of black, grey and white substrata on the growth and attachment strength of Ulva sporelings on glass and polydimethylsiloxane (Silastic-T2) surfaces. The rate of development of sporelings was strongly influenced by the colour of the substratum on which they grew. On black backgrounds, sporelings grew slowly and germination was delayed. Laboratory screening methods for antifouling and fouling-release coatings that rely on the growth of Ulva sporelings can be compromised if samples are of different colours. Hydrodynamic removal of sporelings from coatings may also be affected by substratum colour, since smaller plants generate lower hydrodynamic forces making them more difficult to remove.
Prolonged Corticotropic Action of Synthetic Human ACTH in Man (1976)

The corticotropic activities of synthetic human ACTH (revised structure), synthetic porcine ACTH (unrevised structure) and synthetic 1-24ACTH were compared in 8 normal men by measuring the magnitude and duration of the elevation of plasma 11-hydroxy-corticosteroids following the injection of 1 mg of the peptides. The duration of response was significantly longer after human ACTH than following porcine or 1-24ACTH, although the initial responses were identical. This difference was noted after both intramuscular and intravenous administration. The data suggest that the carboxyterminal of the ACTH peptide is of some importance for biological activity and that biological species specificity may exist.
Digital Systems Simulation (1975)

Early approaches to digital logic simulation were extremely expensive, difficult to use, and plagued with model inaccuracies. Today's simulators have overcome these problems to varying degrees. This situation, combined with the ever-increasing complexity of today's technology, has prompted the acceptance of digital logic simulation as a mandatory tool in most design automation systems.
NF1-L Is the DNA-binding Component of the Protein Complex at the Peripherin Negative Regulatory Element (1995)

The peripherin gene, which encodes a neuronal-specific intermediate filament protein, is transcriptionally induced with a late time course when nerve growth factor stimulates PC12 cells to differentiate into neurons. We have defined a negative regulatory element (NRE) that has a functional role in repressing peripherin expression in undifferentiate and nonneuronal cells. Nerve growth factor-induced derepression of peripherin gene expression is associated with alterations in proteins binding to a GC-rich DNA sequence in the NRE as detected by the DNA electrophoretic mobility shift assay (EMSA). We have utilized DNA affinity chromatography to purify from rat liver a 33-kDa DNA-binding protein that specifically recognizes the NRE. Microsequencing reveals identity with NF1-L, a member of the CTF/NF-1 transcription factor family. This protein forms a single complex when incubated with the NRE probe using EMSA analysis. The more slowly migrating complexes characteristic of crude undifferentiated PC12 cell extract are reconstituted by mixing the purified protein with the flow-through from the DNA affinity column, thereby demonstrating that protein-protein interactions are involved in complex formation. Supershift experiments incubating anti-CTF-1 antibody with undifferentiated PC12 cell extract prior to EMSA analysis confirm that NF1-L, or a closely related family member, is the DNA-binding protein component of the multiprotein complex at the NRE.
Effects of Listeria monocytogenes and Yersinia enterocolitica on cytokine gene expression and release from human polymorphonuclear granulocytes and epithelial (HEp-2) cells (1993)

The gene expression and cytokine release of the proinflammatory cytokines interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alpha (TNF-alpha) after infection of human epithelial cells (HEp-2 cells) and polymorphonuclear granulocytes (PMNs) were investigated by using isogenic pairs of Listeria monocytogenes and Yersinia enterocolitica strains. By polymerase chain reaction-assisted mRNA amplification and RNA dot blot analysis, we showed that PMNs and HEp-2 cells expressed enhanced levels of mRNA encoding IL-1 beta, IL-6, and TNF-alpha after bacterial infection. Concomitant with the enhanced mRNA level, an increased secretion rate of IL-1 beta, IL-6, and TNF-alpha from PMNs as assessed by enzyme-linked immunosorbent assay was observed. HEp-2 cells after infection also released IL-6 and TNF-alpha into the cell supernatant, while no IL-1 beta release was detected. Cellular coincubation experiments were carried out with Transwell chambers. Our studies revealed that the coculture of PMNs and HEp-2 cells led to an increased IL-1 beta and IL-6 release. In contrast, after infection with the invasive bacteria, reduced levels of TNF-alpha were measured. Our data show that PMNs secrete the proinflammatory cytokines IL-1 beta, IL-6, and TNF-alpha within some hours after infection with L. monocytogenes and Y. enterocolitica and that cellular interactions with epithelial cells alone via soluble mediators influence the net amount of released proinflammatory cytokines.
Salivary Transcriptome of the North American Medicinal Leech, Macrobdella decora (2010)

A variety of bioactive proteins from medicinal leeches, like species of Hirudo , have been characterized and evaluated for their potential therapeutic biomedical properties. However, there has not previously been a comprehensive attempt to fully characterize the salivary transcriptome of a medicinal leech that would allow a clearer understanding of the suite of polypeptides employed by these sanguivorous annelids and provide insights regarding their evolutionary origins. An Expressed Sequence Tag (EST) library-based analysis of the salivary transcriptome of the North American medicinal leech, Macrobdella decora, reveals a complex cocktail of anticoagulants and other bioactive secreted proteins not previously known to exist in a single leech. Transcripts were identified that correspond to each of saratin, bdellin, destabilase, hirudin, decorsin, endoglucoronidase, antistatin, and eglin, as well as to other previously uncharacterized predicted serine protease inhibitors, lectoxin-like c-type lectins, ficolin, disintegrins and histidine-rich proteins. This work provides a lens into the richness of bioactive polypeptides that are associated with sanguivory. In the context of a well-characterized molecular phylogeny of leeches, the results allow for preliminary evaluation of the relative evolutionary origins and historical conservation of leech salivary components. The goal of identifying evolutionarily significant residues associated with biomedically significant phenomena implies continued insights from a broader sampling of blood-feeding leech salivary transcriptomes.
Amino Acid Side‐chain Hydrophobicity (2002)

Abstract Hydrophobicity is the unfavourable energetics of dissolving nonpolar compounds in water. The hydrophobicities of the 20 amino acid side‐chains are currently described by hydrophobicity scales derived primarily from solubility studies; these scales have provided semiquantitative rationalizations of some properties of native (folded) proteins.
A structurally novel staphylococcal protein A from the V8 strain (1992)

Protein A from the Staphylococcus aureus strain V8 has a molecular mass about 8000 Da less than that of known proteins A. The corresponding gene was cloned and expressed in Escherichia coli. Sequence analysis of this structurally new protein A revealed that it lacked an IgG-binding domain (58 amino acids), and that it also lacked two octapeptide repetitions located in the membrane/wall attaching region. Contrary to what had been proposed previously, the first translated amino acid is probably not a leucine, but very likely a methionine located 12 residues upstream.
Construction of Peer-to-Peer Systems for Knowledge Resource Distribution Using Overlay Clustering of Similar Peers (2009)

Peer-to-Peer (P2P) systems have been attractive solutions for resource distribution and sharing because of their self-organizing and fault-tolerant features. However, due to the decentralized nature, search efficiency is a challenging problem for large scale knowledge resource distribution P2P systems. In this paper, peer-similarity based P2P overlay clustering algorithm is proposed. Simulation results show that search efficiency using overlay clustering of similar peers is substantially improved.
Determination of the migration times of flow measurement markers in CEC (1991)

Abstract The electroosmotic migration times of fructose, water, and phenol have been measured in several solutions. The electroosmotic flow rate was fundamentally dependent on buffer concentration and on the concentration of additives such as sodium chloride; additives such as methanol and sodium dodecylsulfate did not influence the flow rate, yet tetrabutylammonium bromide had a significant effect.
Normal tissue protection for improving radiotherapy: Where are the Gaps? (2012)

Any tumor could be controlled by radiation therapy if sufficient dose were delivered to all tumor cells. Although technological advances in physical treatment delivery have been developed to allow more radiation dose conformity, normal tissues are invariably included in any radiation field within the tumor volume and also as part of the exit and entrance doses relevant for particle therapy. Mechanisms of normal tissue injury and related biomarkers are now being investigated, facilitating the discovery and development of a next generation of radiation protectors and mitigators. Bringing recent research advances stimulated by development of radiation countermeasures for mass casualties, to clinical cancer care requires understanding the impact of protectors and mitigators on tumor response. These may include treatments that modify cellular damage and death processes, inflammation, alteration of normal flora, wound healing, tissue regeneration and others, specifically to counter cancer site-specific adverse effects to improve outcome of radiation therapy. Such advances in knowledge of tissue and organ biology, mechanisms of injury, development of predictive biomarkers and mechanisms of radioprotection have re-energized the field of normal tissue protection and mitigation. Since various factors, including organ sensitivity to radiation, cellular turnover rate, and differences in mechanisms of injury manifestation and damage response vary among tissues, successful development of radioprotectors/mitigators/treatments may require multiple approaches to address cancer site specific needs. In this review, we discuss examples of important adverse effects of radiotherapy (acute and intermediate to late occurring, when it is delivered either alone or in conjunction with chemotherapy, and important limitations in the current approaches of using radioprotectors and/or mitigators for improving radiation therapy. Also, we are providing general concepts for drug development for improving radiation therapy.
Objective and Subjective Outcomes in Surgery for Chronic Sinusitis (2000)

Endoscopic and radiological findings in patients with chronic sinusitis do not always correlate with symptoms. Studies suggest that postoperative endoscopic examination of the sinonasal cavity provides prognostic information regarding the potential for future episodes of sinusitis and the need for revision surgery. It is recommended that findings on nasal endoscopy be included in future outcomes studies on sinusitis.
Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology (2010)

AMD (age-related macular degeneration) is the major cause of blindness in the western world, associated with the formation of extracellular deposits called drusen in the macula, i.e. the central region of the retina. These drusen contain cellular debris and proteins, including components of the complement system such as the regulator CFH (complement factor H); dysregulation of complement is thought to play a major role in the development of AMD. CFH acts through its capacity to recognize polyanionic structures [e.g. sulfated GAGs (glycosaminoglycans)] found on host tissues, and thereby inactivates any C3b that becomes deposited. Importantly, a common polymorphism in CFH (Y402H) has been strongly associated with an increased risk of AMD. This polymorphism, which causes a tyrosine to histidine coding change, has been shown to alter the binding of CFH to sulfated GAGs, as well as to other ligands including C-reactive protein, necrotic cells and bacterial coat proteins. Of these, the change in the GAG-recognition properties of CFH is likely to be of most significance to AMD. Recent research has revealed that the disease-associated 402H allotype interacts less well (compared with 402Y) with binding sites within the macula (e.g. Bruch's membrane), where the GAGs heparan sulfate and dermatan sulfate play a major role in mediating the interaction with CFH. Reduced binding of the 402H allotype could result in impaired regulation of complement leading to chronic local inflammation that may contribute to the accumulation of drusen and thus the initiation, development and progression of AMD.
Design and testing of a novel, low-cost, low-voltage, functional electrical stimulator (2016)

This paper presents the design of a novel, noninvasive, low cost (<; $70), low voltage (<; 46 V maximum output, 3 V power supply), functional electrical stimulation (FES) circuit aimed at upper-limb stroke rehabilitation. The novel component of the circuit is the unique topology. This circuit uses a boost converter in series with an H-bridge to produce the required biphasic pulses. The stimulator is controllable using a range of different microcontrollers. The low voltage used makes this circuit inherently safer than circuits which use much higher voltages, up to 500 V. The circuit has been successfully tested on the bicep muscles of one healthy subject and is capable of inducing flexion of the elbow with as little as 12 V.
Evidence for a Role of the Gut Hormone PYY in the Regulation of Intestinal Fatty Acid-binding Protein Transcripts in Differentiated Subpopulations of Intestinal Epithelial Cell Hybrids (1997)

Peptide tyrosine tyrosine (PYY) is a gut hormone present in endocrine cells in the lower intestine that can be released by the presence of luminal free fatty acids (FFAs). The biological action of this peptide includes inhibition of gut motility and gastrointestinal and pancreatic secretions. Intestinal fatty acid-binding protein (I-FABP) binds FFA and may be involved in their cytosolic trafficking. Quantitative in situ hybridization on heterogeneous populations of small intestinal somatic cell hybrids selected for endogenous I-FABP expression (hBRIE 380i cells) demonstrated a 5-fold increase in I-FABP transcripts in response to PYY (within 6 h) that was confined to clusters of differentiated cells, whereas ribonuclease protection assays performed on heterogeneous populations of these cells showed no significant differences. High affinity PYY receptors, with an IC50 of 5-50 pM, were identified in both differentiated and nondifferentiated cell populations, as determined by competitive binding assays and autoradiography. In situ hybridization of rat ileal tissue also revealed differing patterns of mRNA expression for liver fatty acid-binding protein (L-FABP) and I-FABP. Only I-FABP mRNA was detected in the villus tips. This localization correlated with the expression pattern of I-FABP mRNA in the hBRIE 380i cells where changes in transcripts were observed only in differentiated cells that did not incorporate bromodeoxyuridine. The sustained expression of I-FABP transcripts in the villar tips suggests (unlike L-FABP) that older terminally differentiated cell populations of the mucosa can still be PYY responsive. These studies demonstrate that physiological concentrations of PYY can regulate I-FABP and place this peptide in a key position as part of a feedback system that determines the processing of cytosolic FFA in the enterocyte. In addition, these studies suggest a mechanism whereby luminal agents can modulate expression of proteins in terminally differentiated cells in the gastrointestinal mucosa.
A high throughput test methodology for MCM substrates (2002)

This paper describes a new high throughput test methodology for a new multi-chip module (MCM) substrate. This is based on a new MCM substrate technology which contains interconnects, embedded passive devices, and mixed-signal circuits, currently being developed by the Packaging Research Center at Georgia Tech. The resulting MCM modules are called SLIM (single layer integrated module). In this paper a best methodology for SLIM modules is discussed.
A lateral chromatic aberration correction system for ultrahigh-definition color video camera (2006)

We have developed color camera for an 8k x 4k-pixel ultrahigh-definition video system, which is called Super Hi- Vision, with a 5x zoom lens and a signal-processing system incorporating a function for real-time lateral chromatic aberration correction. The chromatic aberration of the lens degrades color image resolution. So in order to develop a compact zoom lens consistent with ultrahigh-resolution characteristics, we incorporated a real-time correction function in the signal-processing system. The signal-processing system has eight memory tables to store the correction data at eight focal length points on the blue and red channels. When the focal length data is inputted from the lens control units, the relevant correction data are interpolated from two of eights correction data tables. This system performs geometrical conversion on both channels using this correction data. This paper describes that the correction function can successfully reduce the lateral chromatic aberration, to an amount small enough to ensure the desired image resolution was achieved over the entire range of the lens in real time.
Text identification in complex background using SVM (2005)

The paper presents a fast and robust algorithm to identify text in image or video frames with complex backgrounds and compression effects. The algorithm first extracts the candidate text line on the basis of edge analysis, baseline location and heuristic constraints. Support Vector Machine (SVM) is then used to identify text line from the candidates in edge-based distance map feature space. Experiments based on a large amount of images and video frames from different sources showed the advantages of this algorithm compared to conventional methods in both identification quality and computation time.