gebhart/patrepeval huggingface dataset:
Water Deficit Modulates the Response of<i>Vitis vinifera</i>to the Pierce's Disease Pathogen<i>Xylella fastidiosa</i> (2013)

Pierce's disease, caused by the bacterium Xylella fastidiosa, is one of the most devastating diseases of cultivated grape, currently restricted to the Americas. To test the long-standing hypothesis that Pierce's disease results from pathogen-induced drought stress, we used the Affymetrix Vitis GeneChip to compare the transcriptional response of Vitis vinifera to Xylella infection, water deficit, or a combination of the two stresses. The results reveal a redirection of gene transcription involving 822 genes with a minimum twofold change (P < 0.05), including the upregulation of transcripts for phenylpropanoid and flavonoid biosynthesis, pathogenesis-related proteins, abscisic acid- and jasmonic acid-responsive biosynthesis, and downregulation of transcripts related to photosynthesis, growth, and nutrition. Although the transcriptional response of plants to Xylella infection was largely distinct from the response of healthy plants to water stress, we find that 138 of the pathogen-induced genes exhibited a significantly stronger transcriptional response when plants were simultaneously exposed to infection and drought stress, suggesting a strong interaction between disease and water deficit. This interaction between drought stress and disease was mirrored in planta at the physiological level for aspects of water relations and photosynthesis and in terms of the severity of disease symptoms and the extent of pathogen colonization, providing a molecular correlate of the classical concept of the disease triangle in which environment impacts disease severity.
A Randomized Comparison ofExternal and Internal Cardioversion ofChronic Atrial Fibrillation (1992)

Background. Delivery ofshocks within theright atriumhasbeenreported tobemore effective than conventional external shocks inconverting atrial fibrillation (AF), butthese twocardioversion techniques haveneverbeencompared prospectively. Thepurposeofthisstudy was tocompare theefficacies of external andinternal cardioversion inpatients withchronic AF unresponsive topriorattempts at electrical and/or pharmacological cardioversion. Low-dose amiodarone was usedinallpatients after cardioversion tosuppressrecurrencesofAF. Methods andResults. Onehundredtwelve patients withAF ofatleast 1monthinduration were randomly assigned toundergo external cardioversion with300-360-J shocks orinternal cardioversion with200-300-J shocksdelivered through a standard electrode catheter within theright atrium. The patients were treated withamiodarone (200mg/day5-7days/week) for1 monthbefore electrical cardioversion andafterward ifthecardioversion was successful. Thepatients were-evaluated atregular intervals during 1yearoffollow-up. Theefficacy ofinternal cardioversion was significantly greater than thatofexternal cardioversion (91%versus67%,p=0.002). Theonlyvariable that was associated withthe outcomeofcardioversion was bodyweight. Amongpatients inwhom sinusrhythmwas restored, AF recurred asoften after internal andexternal cardioversion; at1yearoffollow-up, 37%ofpatients inwhom external or internal cardioversion hadbeeneffective were still insinusrhythm. Patients whohad undergone an attempt atelectrical cardioversion before entry intothisstudy wereless likely toremainin sinusrhythmafter cardioversion. Theonlycomplications ofcardioversion were one instance ofcerebral thromboembolism after external cardioversion andone instance oftransient pulmonary edemaafter internal cardioversion. Therapy withamiodarone was discontinued because ofan adverse drugeffect in onlythreepatients. Conclusions. Internal cardioversion ismore effective thanexternal cardioversion inrestoring sinus rhythmandisassafe asexternal cardioversion inpatients withchronic AF.TherecurrencerateofAF isthesame after bothtypes ofcardioversion. Ifconventional electrical cardioversion isineffective, internal cardioversion should be attempted. Thecombination oflow-dose amiodarone andexternal or internal cardioversion may result inmaintaining sinusrhythmlong-term inpatients withrefractory AF. (Circulation 1992;86:1415-1420)
Fabrication of polyimide composite films based on carbon black for high‐temperature resistance (2014)

A novel high‐performance material, carbon black (CB) polyimide (PI), was obtained by the chemical synthesis of CB (carbon black N326) with PI. Following its synthesis, several analyses were carried out to investigate the thermal and mechanical properties of the newly synthesized CB‐PI. The thermal decomposition temperature of CB‐PI compared to PI increased by 76°C from 508 to 584°C. The glass transition temperature of CB‐PI as evaluated by differential scanning calorimetry increased by 204°C from 379 to 583°C compared to that of PI. Moreover, the mechanical strength of CB‐PI increased by 16% compared to that of PI. In addition, the analyses confirm that CB and PI in the synthesized CB‐PI were chemically crosslinked, which was shown to be responsible for the superior thermal and mechanical properties of the CB‐PI. POLYM. COMPOS., 35:2214–2220, 2014. © 2014 Society of Plastics Engineers
Diagnosis of pancreatic carcinoma: role of FDG PET. (1998)

FDG PET is a sensitive and specific noninvasive technique for the diagnosis of pancreatic malignancy.
Antithrombin III Budapest: a single amino acid substitution (429Pro to Leu) in a region highly conserved in the serpin family (1992)

Antithrombin III (AT) is a major plasma serine protease inhibitor and a member of the serpin family of proteins. We have characterized the molecular and genetic basis of AT Budapest, an inherited variant of AT that is associated with thrombotic disease in affected family members. A single amino acid substitution, 429Pro to Leu, was identified, occurring in a region of the molecule that is highly conserved in members of the serpin family. Two forms of variant protein were present in approximately equal amounts in the plasma of the propositus, who is homozygous for the mutation. One form, which had apparently normal Mr, bound heparin strongly and retained some residual thrombin inhibitory activity. The other form had only weak heparin affinity and no antiproteinase activity, and had slightly decreased mobility on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions; this normalized in the presence of a reducing agent, suggesting it was caused by a change in conformation. Additional support for a difference in conformation of the two forms of variant was provided by the finding that the fraction that bound heparin- Sepharose was recognized by a monoclonal antibody raised against normal AT, whereas the weak-affinity fraction was not.
Post-transcriptional regulation of RNA polymerase II levels in Caenorhabditis elegans. (1993)

To investigate the regulation of RNA polymerase II levels in Caenorhabditis elegans, we have constructed nematode strains having one, two, or three copies of ama-1, the gene for the largest subunit of RNA polymerase II. Steady-state levels of RNA polymerase II polypeptides and solubilized enzyme activity are invariant with gene dosage, indicating regulatory compensation. However, steady-state levels of ama-1 mRNA are directly proportional to gene dosage. These results imply that RNA polymerase II levels in C. elegans are regulated post-transcriptionally.
EM-Based Design of Large-Scale Dielectric-Resonator Filters and Multiplexers by Space Mapping (2004)

A novel design methodology for filter and multiplexer design is presented. For the first time, finite-element electromagnetic (EM)-based simulators and space-mapping optimization are combined to produce an accurate design for manifold-coupled output multiplexers with dielectric resonator (DR) loaded raters. Finite-element EM-based simulators are used as a fine model of each multiplexer channel, and a coupling matrix representation is used as a coarse model. Fine details such as tuning screws are included in the fine model. The DR filter and multiplexer design parameters are kept bounded during optimization. The sparsity of the mapping between the design parameters and the coupling elements has been exploited. Our approach has been used to design large-scale output multiplexers and it has significantly reduced the overall tuning time compared to traditional techniques. The technique is illustrated through design of a five-pole DR filter and a ten-channel output multiplexer.
5-(2-Aminoethyl)-2-oxazolidinones with central nervous system depressant and antiinflammatory activity (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT5-(2-Aminoethyl)-2-oxazolidinones with central nervous system depressant and antiinflammatory activityWilliam J. Welstead Jr., Grover C. Helsley, C. Roy Taylor, Lennox B. Turnbull, John P. Da Vanzo, William H. Funderburk, and R. S. AlphinCite this: J. Med. Chem. 1973, 16, 10, 1129–1132Publication Date (Print):October 1, 1973Publication History Published online1 May 2002Published inissue 1 October 1973https://doi.org/10.1021/jm00268a013RIGHTS & PERMISSIONSArticle Views60Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (416 KB) Get e-Alertsclose Get e-Alerts
In-Depth Colloidal Dispersion Gels Improve Oil Recovery Efficiency (1994)

Abstract In the Rocky Mountain Region, a unique in-depth permeability modification process was applied to 29 field projects over the last 9 years. The process involves continuous, long term injection of environmentally sound colloidal dispersion gels. These gels provide a solution to in-depth channeling and crossflow problems inherent with waterflooding, which cannot be solved by near-wellbore gels. Use of colloidal dispersion gels in the field has never before been reported, yet the process has proven to have a phenomenal impact on efficiency of enhanced oil recovery projects. 22 of the projects were considered successful, resulting in improved oil recovery and reduced water production. Seven of the field projects were considered unsuccessful for a variety of reasons. Both successful and unsuccessful treatments are discussed, as both provide valuable insight into treatment design and application. Ultimate oil recoveries in successful treatments are in excess of 40% OOIP, in highly heterogeneous matrix reservoirs with Dykstra-Parsons permeability variations on the order of 0.80. Chemical costs of $1.00 to $2.00/BBL incremental oil recovered are typical, and this cost has decreased below $1.00 in more recent floods due to improved technology. The colloidal dispersion gel process was applied successfully at bottom hole temperatures up to 202 °F. Oil viscosities are often high, from 10 cps to more than 20 cps at the reservoir bottom hole temperature. This paper provides a complete picture of project development from start to finish, including initial laboratory design, project selection criteria, field design, field implementation and project performance. The in-depth colloidal dispersion gel process is a versatile process that has proven an effective tool in long term enhanced oil recovery programs.
Global Illness and Deaths Caused by Rotavirus Disease in Children (2003)

To estimate the global illness and deaths caused by rotavirus disease, we reviewed studies published from 1986 to 2000 on deaths caused by diarrhea and on rotavirus infections in children. We assessed rotavirus-associated illness in three clinical settings (mild cases requiring home care alone, moderate cases requiring a clinic visit, and severe cases requiring hospitalization) and death rates in countries in different World Bank income groups. Each year, rotavirus causes approximately 111 million episodes of gastroenteritis requiring only home care, 25 million clinic visits, 2 million hospitalizations, and 352,000-592,000 deaths (median, 440,000 deaths) in children <5 years of age. By age 5, nearly every child will have an episode of rotavirus gastroenteritis, 1 in 5 will visit a clinic, 1 in 65 will be hospitalized, and approximately 1 in 293 will die. Children in the poorest countries account for 82% of rotavirus deaths. The tremendous incidence of rotavirus disease underscores the urgent need for interventions, such as vaccines, particularly to prevent childhood deaths in developing nations.
Monocular Long-Term Target Following on UAVs (2016)

In this paper, we investigate the challenging long-term visual tracking problem and its implementation on Unmanned Aerial Vehicles (UAVs). By exploiting the inherent correlation between Frequency tracker And Spatial detector, we propose a novel tracking algorithm, denoted as FAST. As can be theoretically and analytically shown, the superior performance of FAST originates from: 1) robustness – by transforming from frequency tracker to spatial detector, FAST owns comprehensive detector to cover consequential temporal variance/invariance information that inherently retained in tracker, 2) efficiency – the coarse-tofine redetection scheme avoids the training of extra classifier and exhaustive search of location and scale. Experiments testified on tracking benchmarks demonstrate the impressive performance of FAST. In particular, we successfully implement FAST on quadrotor platform to tackle with indoor and outdoor practical scenarios, achieving real-time, automatic, smooth, and long-term target following on UAVs.
MPLS Configuration on Cisco IOS Software (2005)

A complete configuration manual for MPLS, MPLS VPNs, MPLS TE, QoS, Any Transport over MPLS (AToM), and VPLS Understand the crucial Cisco commands for various MPLS scenarios Understand fundamentals of MPLS operation and learn to configure basic MPLS in Frame Relay and ATM-based environments Master fundamentals of MPLS VPN operation including Multiprotocol BGP (MBGP) operation, VPNv4 route exchange, and basic MPLS VPN configuration in the provider network Understand and configure various PE-CE routing protocols in MPLS VPN networks Understand MPLS VPN provisioning in an Inter-provider VPN (Inter-AS) and Carrier Supporting Carrier (CSC) environment Learn MPLS TE and its advanced features Examine AToM with configuration examples for like-to-like and any-to-any L2 VPN implementations and VPLS components and operation, VPLS configuration and verification, and VPLS topologies Learn about MPLS QoS, including configuration and implementation of uniform and short pipe modes MPLS Configuration on Cisco IOS Software is a complete and detailed resource to the configuration of Multiprotocol Label Switching (MPLS) networks and associated features. Through its practical, hands-on approach, youll become familiar with MPLS technologies and their configurations using Cisco IOS Software. MPLS Configuration on Cisco IOS Software covers basic-to-advanced MPLS concepts and configuration. Beyond its emphasis on MPLS, youll learn about applications and deployments associated with MPLS, such as traffic engineering (TE), Layer 2 virtual private networks (VPN), and Virtual Private LAN Service (VPLS). Youll receive practical guidance and deployment scenarios that can be enhanced by re-creation of the setups and configurations demonstrated within this book. Youll move quickly from a brief overview of MPLS technology and basic MPLS configuration on Cisco routers to more advanced topics. Several chapters provide instruction on VPN connectivity options, including implementing Border Gateway Protocol (BGP) in MPLS VPNs. Youll receive configuration guidelines for advanced MPLS implementations such as MPLS TE, quality of service (QoS), and extranet VPNs. Youll learn about implementation of Layer 2 VPNs versus Layer 3 VPNs with Cisco Any Transport over MPLS (AToM). And youll see demonstrations of implementing VPLS on Cisco routers complete with the configurations and platform support. I highly recommend MPLS Configuration on Cisco IOS Software as required reading for those in search of practical guidance of the technology and nuances of configuring MPLS for next-generation networks for voice, video, data, and application service offerings across a wide variety of deployment scenarios. Carlos Dominguez, Senior Vice President, Worldwide Service Provider Operations, Cisco Systems This book is part of the Networking Technology Series from Cisco Press, which offers networking professionals valuable information for constructing efficient networks, understanding new technologies, and building successful careers.
Biological Aspects of TiNi Alloy Surfaces (1995)

A review on biocompatibility of TiNi alloys and related surface properties is presented. TiNi alloys showed biocompatibility comparable to that of stainless steel in in vivo and to titanium and Co-Cr alloys in in vitro. The nature of good biocompatibility is related to the properties of TiNi surfaces which revealed the tendency to be covered with TiO2 based oxides with a little amount of Ni (0-5%) in them. Estimations of the concentrations of both alloy components in the biological media after exposure to autoclaved TiNi specimens indicate that release of metals may be biologically insignificant.
<title>Defect topographic maps using a non-Lambertian photometric stereo method</title> (2002)

Industrial applications related to semiconductor wafer fabrication, such as Automatic Defect Classification (ADC), require reliable and rapid measurements of defect characteristics, typically within one second or less. Generally, ADC makes intensive use of 2D defect descriptors such as size or texture. Incorporation of 3D defect descriptors into the classifier can improve the ability to get a fast identification of the exact process step at which a given defect was introduced. Such 3D descriptors can be readily elucidated form a Defect Topographic Map (DTM), which holds the defect's complete 3D representation. In this paper, we introduce an approach for obtaining the DTM form a combination of a non-Lambertian reflectance function with a photometric stereo method (PSM), based on Multiple Perspective SEM Imaging. We also introduce a rapid map generation method based on the Fast Fourier Transform, which we name the Fourier Defect Topographic Map (FDTM). The FDTM exhibits good spatial performance as well as reduced computational requirements. Finally, we discus the detrimental effects of SEM material contrast effects on the generation of topographic maps. We show that effects such as shadowing and noise, can be readily overcome when using MPSI images, resulting in high-quality 3D defect representation.
Density of GM3 with Normal Primary Structure Determines Mouse Melanoma Antigenicity; a New Concept of Tumor Antigen (1989)

We attempted to induce anti-melanoma cytotoxic T cells (CTL) and suppressor T cells (Ts) inhibiting CTL generation by using liposomes carrying various densities of GM3 as tumor antigens. We found that liposomes carrying 6-16 mol% of GM3 with normal primary structure successfully generated anti-melanoma CTL and suppressor T cells, while liposomes with GM3 outside this range had little or no such activity. Anti-melanoma CTL induced by GM3(NeuGc)-liposomes belonged to CD4-/CD8- double-negative CD3+ CTL while GM3(NeuAc)-liposomes induced two types of T cells, CD4+ T cells and double-negative I-J positive T cells which mediated inhibition of the induction of anti-melanoma CTL responses. These cell types were the same as those induced by mitomycin C-treated melanoma cells for CTL induction and soluble melanoma antigen for Ts generation. The results clearly demonstrate that even GM3 with normal primary structure can, at a certain density, generate melanoma antigenicity.
BSML: A Binding Schema Markup Language for Data Interchange in Problem Solving Environments (2003)

We describe a binding schema markup language (BSML) for describing data interchange between scientific codes. Such a facility is an important constituent of scientific problem solving environments (PSEs). BSML is designed to integrate with a PSE or application composition system that views model specification and execution as a problem of managing semistructured data. The data interchange problem is addressed by three techniques for processing semistructured data: validation, binding, and conversion. We present BSML and describe its application to a PSE for wireless communications system design.
Embryonic Pig Pancreatic Tissue for the Treatment of Diabetes: Potential Role of Immune Suppression With “Off-the-Shelf” Third-Party Regulatory T Cells (2010)

Considering the technical difficulties encountered in the generation of Tregs from patients or from specific donors, our results demonstrate the feasibility of using "off-the-shelf" fresh or frozen third-party Tregs to control rejection in organ transplantation.
A novel fast balance technique for the digital AC bridge (1998)

A wide range, fast balance technique for digital AC bridges is proposed in this paper. We introduce a novel method that can give the balance parameters of a digital AC bridge in a closed form. Unlike the traditional heuristic methods used to balance AC bridges, the proposed method only needs to arbitrarily change one adjustable parameter two times including the setting of original values. The balance parameters can then be computed using two closed-form formulas. Finally, the applicability of the proposed theory is discussed, and simulation examples are given and analyzed. Our algorithm is noniterative and precise and offers clear benefits for real-world applications.
Relative orientation revisited (1991)

Relative orientation is the recovery of the position and orientation of one imaging system relative to another from correspondences among five or more ray pairs. It is one of four core problems in photogrammetry and is of central importance in binocular stereo as well as in long-range motion vision. While five ray correspondences are sufficient to yield a finite number of solutions, more than five correspondences are used in practice to ensure an accurate solution with least-squares methods. Most iterative schemes for minimizing the sum of the squares of weighted errors require a good guess as a starting value. The author has previously published a method that results in the best solution without requiring an initial guess [ J. Opt. Soc. Am. A4, 629 ( 1987)] An even simpler method is presented here that utilizes the representation of rotations by unit quaternions.