gebhart/patrepeval huggingface dataset:
Major pertussis‐toxin‐sensitive GTP‐binding protein of bovine lung (1988)

Two GTP-binding proteins which can be ADP-ribosylated by islet-activating protein, pertussis toxin, were purified from the cholate extract of bovine lung membranes. Both proteins had the same heterotrimeric structure (alpha beta gamma), but the alpha subunits were dissociated from the beta gamma when they were purified in the presence of AlCl3, MgCl2 and NaF. The molecular mass of the alpha subunit of the major protein (designated GLu, with beta gamma) was 40 kDa and that of the minor one was 41 kDa. The results of peptide mapping analysis of alpha subunits with a limited proteolysis indicated that GLu alpha was entirely different from the alpha of brain Gi or Go, while the 41-kDa polypeptide was identical with the alpha of bovine brain Gi. The kinetics of guanosine 5'-[3-O-thio]triphosphate (GTP[gamma S]) binding to GLu was similar to that to lung Gi but quite different from that to brain Go. On the other hand, incubation of GLu alpha at 30 degrees C caused a rapid decrease of GTP[gamma S] binding, the inactivation curve being similar to that of Go alpha but different from that of Gi alpha. The alpha subunits of lung Gi and GLu did not react with the antibodies against the alpha subunit of bovine brain Go. The antibodies were raised in rabbits against GLu alpha and were purified with a GLu alpha-Sepharose column. The purified antibodies reacted not only with GLu alpha but also with the 41-kDa protein and purified brain Gi alpha. However, the antibodies adsorbed with brain Gi alpha reacted only with GLu alpha, indicating antisera raised with GLu alpha contained antibodies that recognize both Gi alpha and GLu alpha, and those specific to GLu alpha. These results further indicate that GLu is different from Gi or Go. Anti-GLu alpha antibodies reacted with the 40-kDa proteins in the membranes of bovine brain and human leukemic (HL-60) cells. The beta gamma subunits were also purified from bovine lung. The beta subunit was the doublet of 36-kDa and 35-kDa polypeptides. The lung beta gamma could elicit the ADP-ribosylation of GLu alpha by islet-activating protein, increase the GTP[gamma S] binding to GLu and protect the thermal denaturation of GLu alpha. The antibodies raised against brain beta gamma cross-reacted with lung beta but not with lung gamma.
ChemInform Abstract: GEMINAL DIPHOSPHONIC ACIDS CONTAINING AMIDINE GROUPS (1982)

Abstract Die Reaktion von Säureamiden oder Nitrilen mit PCl 3 /H3PO3 führt in einigen Fällen zur Bildung von Amidinoalkylidendiphosphonsäuren.
Quantum Plasmon Resonances Controlled by Molecular Tunnel Junctions (2014)

Quantum tunneling between two plasmonic resonators links nonlinear quantum optics with terahertz nanoelectronics. We describe the direct observation of and control over quantum plasmon resonances at length scales in the range 0.4 to 1.3 nanometers across molecular tunnel junctions made of two plasmonic resonators bridged by self-assembled monolayers (SAMs). The tunnel barrier width and height are controlled by the properties of the molecules. Using electron energy-loss spectroscopy, we directly observe a plasmon mode, the tunneling charge transfer plasmon, whose frequency (ranging from 140 to 245 terahertz) is dependent on the molecules bridging the gaps.
Image Tubes and Techniques in Television Film Camera Chains (1951)

In this country the iconoscope is used almost universally for motion picture film camera chains. In Europe the flying-spot scanner has recently come into extensive use. Other pickup devices, storage and nonstorage, such as the image orthicon, image iconoscope and image dissector tube, have been used experimentally or in a limited commercial way. The characteristics of each of these tubes and their associated equipment are discussed, and certain advantages are evaluated with respect to such factors as signal-to-noise ratio, spurious signals, spectral response and transfer characteristic.
Public Participation Geographic Information Systems: A Literature Review and Framework (2006)

Abstract Public participation geographic information systems (PPGIS) pertains to the use of geographic information systems (GIS) to broaden public involvement in policymaking as well as to the value of GIS to promote the goals of nongovernmental organizations, grassroots groups, and community-based organizations. The article first traces the social history of PPGIS. It then argues that PPGIS has been socially constructed by a broad set of actors in research across disciplines and in practice across sectors. This produced and reproduced concept is then explicated through four major themes found across the breadth of the PPGIS literature: place and people, technology and data, process, and outcome and evaluation. The themes constitute a framework for evaluating current PPGIS activities and a roadmap for future PPGIS research and practice. Key Words: community-based organizationsgeographic information systemsgrassroots groupsPPGISsocial construction Notes 1. Variants on PPGIS include participatory geomatics or participatory geographic information technologies (participatory GIT), the latter to include GIS, GPS, remote sensing software, and spatial data. 2. I am grateful to Nicholas Chrisman and Francis Harvey for this formulation.
Bio- and photodegradable copolymers derived from low-cost feedstocks (1989)

These results indicate that GATA3 is an independent prognostic factor and suggest that evaluation of GATA3 expression might enable more effective clinical follow-up using prognostic stratification of STS patients.
Tissue approximation in endoscopic surgery (1995)

1. KNOTTING 2. Nomenclature and Fundamental Principles of Knot Tying 3. Suture and Ligature Materials 4. External Slip Knots and Pre-Formed Slipping Endoloops 5. Intracorporeal Knots in Endoscopic Surgery 6. Philosophy and Setup 7. SUTURING 8. Principles and Techniques of Laparoscopic Stitch Placement 9. Equipment and Instrumentation for Laparoscopic Suturing 10. Laparoscopic Hand Sutures and Stapled Anastomoses 11. Closure of Laparoscopic Access Wounds 12. Training 13. Future Advances in Tissue Approximation
Normal Width of Cranial Sutures in the Neonate and Infant (1976)

A material of 107 normal skull films have been used to determine the normal range of the cranial sutures in the age group 0 to 45 days of age. Assessment is based on the lateral view and includes evaluation of both coronal and lambdoid sutures as well as the degree of V-shape of the coronal sutures. Values obtained are easily classified as normal, borderline or pathologic by use of a simple diagram.
Prediction of protein interaction sites from sequence profile and residue neighbor list (2001)

Protein-protein interaction sites are predicted from a neural network with sequence profiles of neighboring residues and solvent exposure as input. The network was trained on 615 pairs of nonhomologous complex-forming proteins. Tested on a different set of 129 pairs of nonhomologous complex-forming proteins, 70% of the 11,004 predicted interface residues are actually located in the interfaces. These 7732 correctly predicted residues account for 65% of the 11,805 residues making up the 129 interfaces. The main strength of the network predictor lies in the fact that neighbor lists and solvent exposure are relatively insensitive to structural changes accompanying complex formation. As such, it performs equally well with bound or unbound structures of the proteins. For a set of 35 test proteins, when the input was calculated from the bound and unbound structures, the correct fractions of the predicted interface residues were 69 and 70%, respectively.
Leveraging Zipf's law for traffic offloading (2012)

Internet traffic has Zipf-like properties at multiple aggregation levels. These properties suggest the possibility of offloading most of the traffic from a complex controller (e.g., a software router) to a simple forwarder (e.g., a commodity switch), by letting the forwarder handle a very limited set of flows; the heavy hitters. As the volume of traffic from a set of flows is highly dynamic, maintaining a reliable set of heavy hitters over time is challenging. This is especially true when we face a volume limit in the non-offloaded traffic in combination with a constraint in the size of the heavy hitter set or its rate of change. We propose a set selection strategy that takes advantage of the properties of heavy hitters at different time scales. Based on real Internet traffic traces, we show that our strategy is able to offload most of the traffic while limiting the rate of change of the heavy hitter set, suggesting the feasibility of alternative router designs.
Molecular cloning of the chicken avidin cDNA (1987)

A cDNA for chicken avidin was identified in a chicken oviduct cDNA library by screening with antibodies and synthetic oligodeoxyribonucleotides. Four recombinant clones were characterized and each contained the sequence of the oligonucleotide probes used in screening. They were capable also of expressing an antigen recognizable by a polyclonal or a mixture of monoclonal antibodies raised against avidin. The longest clone, lambda cAV4, contained the entire coding sequence of avidin along with a signal peptide of 24 amino acids. An avidin mRNA, approximately 700 nucleotides in length, was induced by a single injection of progesterone over a period of twenty four hours. The avidin mRNA was distributed in a tissue-specific manner, since detectable concentration of the mRNA appeared only in the oviduct after stimulation with progesterone alone or with a combination of progesterone and estrogen. No avidin mRNA was detected in the liver or kidney under these conditions. Preliminary results on the genomic complexity of avidin suggest a single copy gene. Isolation of the natural gene for avidin and studies on its regulation now can be initiated using the cDNA probe.
<title>MOEM scan engine for bar code reading and factory automation</title> (1998)

Rockwell is in the state of technology transfer to manufacturing of a micro-opto-electro-mechanical scan engine with superior scanning performance for bar code reading and factory automation. The scan engine consists of three main components: actuator, mirrors, and control electronics. The first two components are fabricated on a silicon cantilever beam while the control electronics are presently hybrid. The actuator comprises of a bimorph layer covered with two metal layers. The mirror has a large area (several mm<SUP>2</SUP>) and it is micromachined with a surface flatness better than (lambda) /2. Actuator scan-angles greater than 22 degree(s) with high repeatability in performance are achieved. The scan engine was integrated with an existing Rockwell commercial bar code reader/decoder and successfully proven to read a two-character code 39 bar code. The system was capable of decoding the 13-mil label at 360 scans per second with a 100% successful read performance. Environmental testing of the device indicates that the scanner can operate at elevated temperatures up to 70 degree(s)C with minor fluctuations in frequency and scan angle. The scanner has also gone through a lifetime cycle test and it has survived more than 8 billion cycles during a period of 18 months. To increase the yield and the performance level of the device, theoretical study as well as dynamic simulation by finite elements modeling have been investigated and will be reported separately.
Vapor-liquid equilibrium relations in non-ideal systems. The binary systems: hexamethyldisiloxane-toluene hexamethyldisiloxane-ethyl alcohol and ethyl alcohol-toluene at 40,50,60, and 70C / (1973)

The following explanation of techniques is provided to help you understand markings or patterns which may appear on this reproduction.1.T he sign or "target" for pages apparently lacking from the document photographed is "Missing Page{s)".If it was possible to obtain the missing page(s) or section, they are spliced into the film along with adjacent pages.This may have necessitated cutting thru an image and duplicating adjacent pages to insure you complete continuity.2. When an imaga on the film is obliterated with a large round black mark, it is an indication th at the photographer suspected th a t the copy may have moved during exposure and thus cause a blurred image.You will find a good image of the page in the adjacent frame.3. When a map, drawing or chart, etc., was part of the material being photographed the photographer followed a definite method in "sectioning" the material.It is customary to begin photoing a t the upper left hand corner of a large sheet and to continue photoing from left to right in equal sections with a small overlap.If necessary, sectioning is continued again -beginning below the first row and continuing on until complete.4. The majority of users indicate th at the textual content is of greatest value, however, a somewhat higher quality reproduction could be made from "photographs" if essential to the understanding of the dissertation.
Generation of Continuous Variable Einstein-Podolsky-Rosen Entanglement via the Kerr Nonlinearity in an Optical Fiber (2001)

We report on the generation of a continuous variable Einstein-Podolsky-Rosen (EPR) entanglement using an optical fiber interferometer. The Kerr nonlinearity in the fiber is exploited for the generation of two independent squeezed beams. These interfere at a beam splitter and EPR entanglement is obtained between the output beams. The correlation of the amplitude (phase) quadratures is measured to be 4.0+/-0.2 (4.0+/-0.4) dB below the quantum noise limit. The sum criterion for these squeezing variances 0.80+/-0.03<2 verifies the nonseparability of the state. The product of the inferred uncertainties for one beam (0.64+/-0.08) is well below the EPR limit of unity.
Hyperplasia and carcinoma of the endometrium. (1988)

Published criteria for classifying endometrial hyperplasias and their differential diagnosis from well-differentiated endometrioid-type adenocarcinoma are reviewed, and the author's own interpretations and recommendations are presented. Also discussed are the subjects of misdiagnosis of hyperplasia and carcinoma, premalignant significance of hyperplasia, and prognostic significance of hyperplasia in patients with carcinoma patients.
Target cells for granulocyte colony-stimulating factor, interleukin-3, and interleukin-5 in differentiation pathways of neutrophils and eosinophils (1990)

Abstract To study the relationship between hematopoietic factors and their responsive hematopoietic progenitors in the differentiation process, both purified factors and enriched progenitors are required. We isolated total CD34+ cells, CD34+,CD33+ cells, and CD34+,CD33- cells individually from normal human bone marrow cells by fluorescence- activated cell sorter (FACS), and examined the effects of granulocyte colony-stimulating factor (G-CSF), interleukin-3 (IL-3), and IL-5 on in vitro colony formation of these cells. CD34+,CD33+ cells formed granulocyte colonies in the presence of G-CSF. Both CD34+,CD33+ cells and CD34+,CD33- cells formed granulocyte/macrophage colonies in the presence of IL-3. Eosinophil (Eo) colonies were only formed by CD34+,CD33- cells in response to IL-3, but scarcely formed by CD34+ cells in the presence of IL-5. We performed the two-step cultures consisting of the primary liquid culture for 6 days and the secondary methylcellulose culture, and serially examined changes in phenotypes of ,he cells cultured in the primary culture. CD34-,CD33+ cells derived from CD34+,CD33+ cells by preincubation with G-CSF or IL-3 formed Eo colonies in the presence of IL-5 but not IL-3. CD34-,CD33+ cells derived from CD34+,CD33- cells by preincubation with IL-3 also formed Eo colonies by support of IL-5 as well as IL-3. Both CD34+ cells gradually lost the CD34 antigen by day 6 of incubation with G-CSF or IL- 3. Loss of this antigen was well-correlated with acquisition of susceptibility to IL-5. It was concluded that G-CSF supported the neutrophil differentiation of committed colony-forming cells, IL-3 supported that of both committed and multipotent colony-forming cells. G-CSF and IL-3 also supported the early stage of E. differentiation; IL- 5 supported the late stage of that.
SARS-CoV-2 Titers in Wastewater Are Higher than Expected from Clinically Confirmed Cases (2020)

Wastewater surveillance represents a complementary approach to clinical surveillance to measure the presence and prevalence of emerging infectious diseases like the novel coronavirus SARS-CoV-2. This innovative data source can improve the precision of epidemiological modeling to understand the penetrance of SARS-CoV-2 in specific vulnerable communities. Here, we tested wastewater collected at a major urban treatment facility in Massachusetts and detected SARS-CoV-2 RNA from the <i>N</i> gene at significant titers (57 to 303 copies per ml of sewage) in the period from 18 to 25 March 2020 using RT-qPCR. We validated detection of SARS-CoV-2 by Sanger sequencing the PCR product from the <i>S</i> gene. Viral titers observed were significantly higher than expected based on clinically confirmed cases in Massachusetts as of 25 March. Our approach is scalable and may be useful in modeling the SARS-CoV-2 pandemic and future outbreaks.<b>IMPORTANCE</b> Wastewater-based surveillance is a promising approach for proactive outbreak monitoring. SARS-CoV-2 is shed in stool early in the clinical course and infects a large asymptomatic population, making it an ideal target for wastewater-based monitoring. In this study, we develop a laboratory protocol to quantify viral titers in raw sewage via qPCR analysis and validate results with sequencing analysis. Our results suggest that the number of positive cases estimated from wastewater viral titers is orders of magnitude greater than the number of confirmed clinical cases and therefore may significantly impact efforts to understand the case fatality rate and progression of disease. These data may help inform decisions surrounding the advancement or scale-back of social distancing and quarantine efforts based on dynamic wastewater catchment-level estimations of prevalence.
[Effect of puerarin on coronary collateral circulation in dogs with experimental acute myocardial infarction]. (1999)

Puerarin might improve the opening and forming of coronary collateral circulation to ischemic myocardium in dogs and protect ischemic myocardium.
Folding state recognition for multi-foldable mobile devices (2017)

Owing to the advanced technology of flexible electronics, flexible touchscreens have become a reality and could by widely deployed on various devices such as mobile phones, wearable devices, and hand-held tablets. Flexible touchscreens not only realize the concept of multi-foldable mobile devices but also significantly change the user experiences due to its flexibility. For instance, when the foldable device is folded, the visible and accessible area of the touchscreen is changed accordingly. The change in displayed area could hinder accessibility to some objects on the touchscreens. Therefore, how to identify the folding state of the touchscreen and adjust the display accordingly becomes a critical issue. To resolve this critical problem, a folding state recognition software stack is designed and implemented to detect the folding type of the touchscreens. The technique difficulty lies in how to distinguish the folding state via multiple accelerometer/gyroscope sensors.
FPGAs make a radar signal processor on a chip a reality (2003)

Radar signal processors heavily tax the capabilities of conventional microprocessor based signal processing systems. Higher performance systems using custom silicon cost too much for the typically small production volumes, and are not flexible enough for research applications. Field programmable gate arrays offer the performance of custom silicon while maintaining the economies and flexibility of the microprocessor based solutions. Recent devices possess the density and performance to realize a complete radar signal processor in a single FPGA, including complex down-conversion of the IF to base-band. Performing the down-conversion and matched filtering in the FPGA eliminates the specialty chips previously needed for these functions, making it possible to use commercially available FPGA boards. Our system packs 4 channels into a pair of FPGAs. Each channel (a demodulator, a matched filter and a Doppler pulse pair processor) executes over 5 billion multiplies per second.
Laser heat treatment of gas-nitrided layer produced on 42CrMo4 steel (2015)

Wydawnictwo SIGMA-NOT wydaje czasopisma fachowe informujące swoich czytelników o najnowszych osiągnięciach naukowych i nowoczesnych rozwiązaniach technicznych w Polsce i na świecie, popularyzuje problemy techniczne oraz poszerza wiedzę i kulturę techniczną.
Pitfalls in the CT Diagnosis of Atlantoaxial Rotary Subluxation (1987)

CT was used to examine six patients with clinically evident atlantoaxial rotary fixation, two patients with torticollis, and six normal subjects who had turned their heads to the side as far as voluntarily possible. The CT appearances of the atlantoaxial complex were identical in all three groups. To differentiate these groups, we propose a functional scan through C1–C2 in which patients are scanned initially as they present, with their heads fixed in lateral rotation. Subsequent scans are obtained with their heads turned to the maximum contralateral rotation. CT scans in patients with atlantoaxial rotary fixation demonstrate no motion at C1–C2 during this maneuver, while those in patients with transient torticollis show a reduction or reversal of the rotation of C1 on C2.
TRANS‐URETERO‐URETEROSTOMY <sup>1</sup> (1969)

SUMMARY The management of ureteral injuries in two previous series has been reviewed. All operations except reimplantation into the bladder were found to give bad results or to cause unnecessary sacrifice of kidneys. Twelve trans‐uretero‐ureterostomies for varying indications have all given good results. This operation is simple, has few complications and preserves kidneys consistently and safely. Indications and contra‐indications are suggested. More extensive assessment of the operation is recommended.
Turbulent Prandtl Number—Where Are We? (1994)

The objective of this paper is to examine critically the presently available experimental data on Turbulent Prandtl Number for the two-dimensional turbulent boundry layer, and for fully developed flow in a circular tube or a flat duct, and attempt to draw some conclusions as to where matters presently stand.
Integrated Designs for Gene Discovery and Characterization (1999)

Recent advances, including near completion of the human genome map, ever improving high-throughput technologies, and successes in discovering chronic disease-related genes, have stimulated the further development of genetic epidemiology. The primary mission of genetic epidemiology is to discover and characterize genes, whether independent of or interactive with environmental factors, that cause human diseases. To accomplish such a mission, genetic epidemiology needs to integrate both genetic and epidemiologic approaches. One of the challenges facing such an integrated approach is the identification of study designs that are efficient for both gene discovery and characterization. Because designs for gene discovery alone and designs for gene characterization alone have been elaborated in the other two panels, the focus of this paper is to describe those designs that may be useful for discovery and characterization jointly, including case-family and case-control-family designs. Examples of integrated designs are described, and studies of breast cancer conducted at the Fred Hutchinson Cancer Research Center are used for illustration. Finally, related analytic issues are also discussed.