gebhart/patrepeval huggingface dataset:
Knowledge Management - an Effective Model to Facilitate the Implementation of 'Ageing in Place' (2004)

'Ageing in place' is the provision of necessary care services to enable frail elderly to stay as long as possible in their own homes. As the care needs fluctuates when an elderly person's health condition deteriorates, managing 'ageing in place' is a significant challenge for the organisation delivering the care. This paper reports how the implementation of a preliminary knowledge management system has facilitated the effective capture, storage, dissemination of knowledge about the assessment for each resident in an 'ageing in place' demonstration village. The new knowledge created through the automatic analysing and reasoning conducted by the program brings the benefit of accurately identifying the needs and changing needs of residents. This facilitates the provision of targeted care. It enables the accurate estimation of the amount of nursing care required, facilitates the continuity of care among various medical teams, such as GPs, emergency and hospital. The explicit knowledge presented by the summary report effectively engages management, care workers and resident in assessment and planning process. The trial demonstrates that properly designed information management system that suits the work practice and information needs of aged care nurse will enable effective management of organisational knowledge to achieve the final goal of best care delivery and service provision. Aged care nurses welcome such practice.
Salt-Induced Homoaggregation of Poly(<i>N</i>-isopropylacrylamide) Microgels (2002)

Microgels of poly(N-isopropylacrylamide), copolymerized with acrylic acid and cross-linked with methylene bisacrylamide, swell at temperatures below 32 °C. Such swollen particles deswell at high salt concentrations, where electrostatic stabilization is eliminated. This results in a system where the strength of the van der Waals attraction, driving homoaggregation, is controlled independently by both temperature and salt concentration. In this paper, the locus of stability for these particles at different temperatures and salt concentrations was determined. Small-angle light scattering studies of the homoaggregating particles revealed a system that changes from diffusion-limited to a mechanism involving particle rearrangement over a small temperature range.
Macrophages Mediate Inflammation-Enhanced Metastasis of Ovarian Tumors in Mice (2007)

The tumor microenvironment is known to have a profound effect on tumor progression in a highly context-specific manner. We have investigated whether peritoneal inflammation plays a causative role in ovarian tumor metastasis, a poorly understood process. Implantation of human ovarian tumor cells into the ovaries of severe combined immunodeficient mice resulted in peritoneal inflammation that corresponds temporally with tumor cell dissemination from the ovaries. Enhancement of the inflammatory response with thioglycolate accelerated the development of ascites and metastases. Suppression of inflammation with acetyl salicylic acid delayed ascites development and reduced tumor implant formation. A similar prometastatic effect for inflammation was observed when tumor cells were injected directly into the peritoneum of severe combined immunodeficient mice, and in a syngeneic immunocompetent mouse model. Inflammation-modulating treatments did not affect primary tumor development or in vitro tumor cell growth. Depletion of peritoneal macrophages, but not neutrophils or natural killer cells, reduced tumor progression, as assessed by ascites formation and peritoneal metastasis. We conclude that inflammation facilitates ovarian tumor metastasis by a mechanism largely mediated by macrophages, and which may involve stromal vascular endothelial growth factor production. The confirmation of these findings in immunocompetent mice suggests relevance to human disease. Identifying the mechanisms by which macrophages contribute to tumor metastasis may facilitate the development of new therapies specifically targeting immune cell products in the tumor microenvironment.
THE EFFECT OF UNIAXIAL STRAIN ON THE THRESHOLD CURRENT AND OUTPUT OF GaAs LASERS (1963)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation F. M. Ryan, R. C. Miller; THE EFFECT OF UNIAXIAL STRAIN ON THE THRESHOLD CURRENT AND OUTPUT OF GaAs LASERS. Appl. Phys. Lett. 1 November 1963; 3 (9): 162–163. https://doi.org/10.1063/1.1753914 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioApplied Physics Letters Search Advanced Search |Citation Search
THE ESTIMATION OF SIMPLE, SOLUBLE CYANOGEN COMPOUNDS, MAKING USE OF THE PRINCIPLE OF AERATION (1923)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE ESTIMATION OF SIMPLE, SOLUBLE CYANOGEN COMPOUNDS, MAKING USE OF THE PRINCIPLE OF AERATIONJoseph H. RoeCite this: J. Am. Chem. Soc. 1923, 45, 8, 1878–1883Publication Date (Print):August 1, 1923Publication History Published online1 May 2002Published inissue 1 August 1923https://pubs.acs.org/doi/10.1021/ja01661a002https://doi.org/10.1021/ja01661a002research-articleACS PublicationsRequest reuse permissionsArticle Views30Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Pressure Measurements on a Deforming Surface in Response to an Underwater Explosion in a Water‐Filled Aluminum Tube (2000)

Experiments have been conducted to benchmark DYSMAS computer code calculations for the dynamic interaction of water with cylindrical structures. Small explosive charges were suspended using hypodermic needle tubing inside Al tubes filled with distilled water. Pressures were measured during shock loading by tourmaline crystal, carbon resistor and ytterbium foil gages bonded to the tube using a variety of adhesives. Comparable calculated and measured pressures were obtained for the explosive charges used, with some gages surviving long enough to record results after cavitation with the tube wall.
Suppression of herpes simplex virus type 1 reactivation from latency by (+-)-9-([(Z)-2-(hydroxymethyl)cyclohexyl]methyl) guanine (L-653,180) in vitro (1990)

Latent herpes simplex virus type 1 (HSV-1) infection was induced in human embryonic lung cells in vitro by using a combination of viral replication inhibitors and elevated temperature. Under reactivating conditions (superinfection by human cytomegalovirus or temperature manipulation), a nonantiviral thymidine kinase inhibitor (L-653,180) was found to suppress or delay reactivation of HSV-1 from latently infected human embryonic lung cells. L-653,180 alone or in combination with interferon was ineffective as a primary or acute viral replication inhibitor and was unable to induce latent HSV-1 infection in cell culture. These data suggest that initial or acute virus replication and replication resulting from reactivation from latency are separate events.
Laboratory Diagnosis of Inherited Protein S Deficiency (1990)

The authors investigated assays for free protein S (ProS) antigen, total ProS antigen, and ProS crossed Immunoelectrophoresis (CIEP) in the diagnosis of type 1 inherited ProS deficiency. Accurate measurement of the hemostatically important free ProS required showing that, on each specimen, precipitation of the C4b-binding protein (C4b-BP)/protein S complex (C4b-BP/ProS) by polyethylene glycol-8,000 (PEG) was complete. The authors showed this by doing a ProS CIEP on the same PEG supernate that was used for quantitative measurement of free ProS. The ±2 standard deviation (±2 SD) ranges for free ProS were 81-133% for males and 50-130% for females. This striking male-female difference has been reported only twice before. With the use of a graph of values for free ProS versus prothrombin time (PT), patients with inherited ProS deficiency segregated cleanly from normals and from patients on warfarin therapy without ProS deficiency until the PT was greater than 20 seconds. There is overlap of total ProS antigen values between normals and patients with inherited ProS deficiency.
Automated generation and evaluation of control programs for discrete manufacturing processes (2003)

A set of software tools is described for specifying the control and process dynamics for discrete manufacturing systems. Specifications are entered and modified in a relational database using a formalism that naturally reflects the functional components of a discrete control system. A Petri-net model of the control and process logic is extracted automatically from the database, and various analysis tools are provided to investigate the consistency and viability of the specifications. The control logic is then translated into source code for the online control computer. The specification formalism and generated control software are illustrated using a simple die-stamping example. A real-time process simulator for program verification is also described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Gaze-Assisted User Authentication to Counter Shoulder-surfing Attacks (2018)

A highly secure, foolproof, user authentication system is still a primary focus of research in the field of User Privacy and Security. Shoulder-surfing is an act of spying when an authorized user is logging into a system, and is promoted by a malicious intent of gaining unauthorized access. We present a gaze-assisted user authentication system as a potential solution to counter shoulder-surfing attacks. The system comprises of an eye tracker and an authentication interface with 12 pre-defined shapes (e.g., triangle, circle, etc.) that move simultaneously on the screen. A user chooses a set of three shapes as a password. To authenticate, the user follows the paths of three shapes as they move, one on each frame, over three consecutive frames. The system uses either the template matching or decision tree algorithms to match the scan-path of the user's gaze with the path traversed by the shape. The system was evaluated with seven users to test the accuracy of both the algorithms. We found that with the template matching algorithm the system achieves an accuracy of 95%, and with the decision tree algorithm an accuracy of 90.2%. We also present the advantages and disadvantages of using both the algorithms. Our study suggests that gaze-based authentication is a highly secure method against shoulder-surfing attacks as the unique pattern of eye movements for each individual makes the system hard to break into.
Characterization of a Heparan Sulfate 3-O-Sulfotransferase-5, an Enzyme Synthesizing a Tetrasulfated Disaccharide (2003)

Heparan sulfate d-glucosaminyl 3-O-sulfotransferases (3-OSTs) catalyze the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 3 of the glucosamine residue of heparan sulfate and heparin. A sixth member of the human 3-OST family, named 3-OST-5, was recently reported (Xia, G., Chen, J., Tiwari, V., Ju, W., Li, J.-P., Malmstrom, A., Shukla, D., and Liu, J. (2002) J. Biol. Chem. 277, 37912-37919). In the present study, we cloned putative catalytic domain of the human 3-OST-5 and expressed it in insect cells as a soluble enzyme. Recombinant 3-OST-5 only exhibited sulfotransferase activity toward heparan sulfate and heparin. When incubated heparan sulfate with [35S]PAPS, the highest incorporation of35S was observed, and digestion of the product with a mixture of heparin lyases yielded two major35S-labeled disaccharides, which were determined as DeltaHexA-GlcN(NS,3S,6S) and DeltaHexA(2S)-GlcN(NS,3S) by further digestion with 2-sulfatase and degradation with mercuric acetate. However, when used heparin as acceptor, we identified a highly sulfated disaccharide unit as a major product. This had a structure of DeltaHexA(2S)-GlcN(NS,3S,6S). Quantitative real-time PCR analysis revealed that 3-OST-5 was highly expressed in fetal brain, followed by adult brain and spinal cord, and at very low or undetectable levels in the other tissues. Finally, we detected a tetrasulfated disaccharide unit in bovine intestinal heparan sulfate. To our knowledge, this is the first report to describe not only the natural occurrence of tetrasulfated disaccharide unit but also the enzymatic formation of this novel structure.
Algorithm animation (1988)

An algorithm animation environment is a means for exploring the dynamic behavior of algorithms that makes possible a fundamental improvement in the way we understand and think about them. It presents multiple graphical views of an algorithm in action, exposing properties that might otherwise be difficult to understand or even remain unnoticed. All views are updated simultaneously in real time as the algorithm executes, and each view is displayed in a separate window on the screen, whose location, size, and level of detail is interactively set by the end-user. A specialized interpreter controls execution in units that are specific to the algorithm, and allows multiple algorithms to be run simultaneously for comparisons. Programmers can implement new algorithms, graphical displays, and input generators and run them with existing libraries of such components.
An important aspect of an algorithm animation environment, and one we believe is useful in any interactive environment, is the concept of a script: a record of an end-user's session that can be replayed. Scripts can be used both passively, as virtual videotapes, and actively, as an innovative communication medium: the viewer of a script can customize the videotape interactively, and can readily switch between passively viewing it and actively exploring its contents. Scripts are typically used as high-level macros, system tutors, and electronic textbooks and research notes. End-users can create scripts easily by instructing the system to watch what I do; scripts are stored as readable and editable PASCAL programs.
The potential of such algorithm animation environments is great, but can be fully realized only if they are sufficiently easy and enjoyable to use. This dissertation is step towards achieving these goals. In it, we develop a model for creating real-time animations, as well as a framework for interacting with these animations. We also describe a prototype system, BALSA-II, and its feasibility study system, BALSA-I, that realize the conceptual model.
Physical Properties of Barrier Ribs of Plasma Display Panels: I, Formation of Pores during Sintering of Lead Borosilicate Glass Frits (2002)

The effects of chemical compositions on the sintering behavior and physical properties of lead borosilicate glass developed for barrier ribs of plasma display panels (PDP) were investigated. The formation of pores during sintering of the glass was noted, and their formation mechanism was investigated using XPS, TG/DTA, and XRD. A change in the oxidation state of the lead was discussed as a possible cause for the formation of pores in the sintered samples.
Chemistry research in Eastern Central Europe (1992-1997) - Facts and figures on publication output and citation impact (2000)

status: Published
Performance Analysis and Optimization for Visible Light Communication with Spatial Modulation (2021)

Recently, visible light communication (VLC) technology has attracted great attention in both academia and industry. In this paper, a spatial modulation (SM) based multiple-input multiple-output (MIMO) VLC system with input-dependent noise is investigated. Based on the input-dependent noise, the theoretical symbol error rate (SER) expression is obtained. The SER performance of SM-based MIMO VLC system is analyzed for both input-dependent noise and input-independent noise cases. Considering the trade-off between SER and transmission rate, the successful transmission rate indicator is formulated, which is the product of SER and transmission rate. An optimization problem, whose goal is to maximize the successful transmission rate, is proposed to optimize the modulation order. Simulation results show the effectiveness of the obtained SER expression. Simulations also indicate that the system with larger input-dependent noise tends to have smaller modulation order in order to maximize the successful transmission rate.
Connective tissue response to tubular implants for peripheral nerve regeneration: The role of myofibroblasts (2000)

The presence of contractile cells, their organization around regenerating nerve trunks, and the hypothetical effect of these organized structures on the extent of regeneration across a tubulated 10-mm gap in the rat sciatic nerve were investigated. Collagen and silicone tubes were implanted both empty and filled with a collagen-glycosaminoglycan (GAG) matrix. Nerves were retrieved at 6, 30, and 60 weeks postoperatively and time-dependent values of the nerve trunk diameter along the tubulated length were recorded. The presence of myofibroblasts was identified immunohistochemically using a monoclonal antibody to alpha-smooth muscle actin. Myofibroblasts were circumferentially arranged around the perimeter of regenerated nerve trunks, forming a capsule which was about 10 times thicker in silicone tubes than in collagen tubes. The nerve trunk diameter that formed inside collagen tubes was twice as large as that inside silicone tubes. In contrast, the collagen-GAG matrix had a relatively small effect on capsule thickness or diameter of regenerate. It was hypothesized that the frequency of successful bridging by axons depends on the balance between two competitive forces: the axial forces generated by the outgrowth of axons and nonneuronal cells from the proximal stump and the constrictive, circumferential forces imposed by the contractile tissue capsule that promote closure of the wounded stumps and prevent axon elongation. Because the presence of the collagen-GAG matrix has enhanced greatly the recovery of normal function of regenerates in silicone tubes, it was hypothesized that it accelerated axonal elongation sufficiently before the hypothetical forces constricting the nerve trunk in silicone tubes became sufficiently large. The combined data suggest a new mechanism for peripheral nerve regeneration along a tubulated gap.
Copper- and Palladium-Catalyzed Amidation Reactions for the Synthesis of Substituted Imidazo[4,5-<i>c</i>]pyridines (2014)

Imidazo[4,5-c]pyridines were synthesized in three steps utilizing a palladium-catalyzed amidation/cyclization strategy. N-Aryl substrates were synthesized using copper-catalyzed amidation of 3-amino-N-Boc-4-chloropyridine. Complementary protocols for the selective chlorination of imidazo[4,5-c]pyridines at the C2 and C7 positions were also developed.
Design and characterization of N<sup>2</sup>-arylaminopurines which selectively inhibit replicative DNA synthesis and replication-specific DNA polymerases: guanine derivatives active on mammalian DNA polymerme alpha and bacterial DNA polymerase III (1982)

The 2-amino substituted derivatives of guanine, N2-(p-n-butylphenyl)guanine (BuPG) and N2-(3',4'-trimethylenephenyl) guanine (TMPG), were synthesized and found to selectively inhibit, respectively, HeLa cell DNA polymerase alpha (po1 alpha) and B. subtilis DNA polymerase III (po1 III). Both purines, like their corresponding uracil analogs, BuAu and TMAU (2,9), were specifically competitive with dGTP in their inhibitory action on their target polymerases. BuPG, the pol alpha-specific purine, was also toxic for HeLa cells in vivo, selectively inhibiting DNA synthesis. These N2-substituted purines, in contrast to the 6-substituted uracils, provide a structural basis for the synthesis of nucleosides and nucleotides with considerable potential as probes for the analysis of the structure of specific replicative DNA polymerases and their function in cellular DNA metabolism.
High-reliability tungsten-stacked via process with fully converted TiAl/sub 3/ formation annealing (1999)

The tungsten-stacked via structure will be widely used in future generations of semiconductors to increase the density of aluminum wiring. One problem with this structure is that film separation is sometimes observed at the interface between the aluminum wiring and the oxide layer. This separation occurs only in the specific stacked via structure, and it carries a risk of a potential reliability of via open problem. Some experiments aimed at solving this separation problem revealed that the stress induced by insufficient TiAl/sub 3/ formation during the heat cycle of metal annealing is strongly related to the film separation. The occurrence of the insufficient TiAl/sub 3/ formation is highly dependent on the condition of the interface between the titanium and aluminum, and it is also dependent on the ambient gas used for the ramp-up step in the metal annealing process. If these processes are optimized properly the stress value of TiAl/sub 3/ formation indicates the position of the maximum stress point during metal annealing. It was demonstrated that monitoring of the maximum stress point is one method for determining whether the TiAl/sub 3/ is fully formed.
Narrative Game-based Learning Objects for Story-based Digital Educational Games (2009)

This paper introduces the concept of Narrative Game-based Learning Objects (NGLOBs) as the basis for the creation and control of Story-based Digital Educational Games (DEGs). In the context of the European research project 80Days, section 1 describes major aims and challenges of Story-based DEGs and motivates for the introduction and use of NGLOBs. In the main part, section 2 provides an overview of the conceptualization of NGLOBs and their formalization within ICML as an XML-based format for Story-based applications and DEGs. In section 3 the theoretical results are set in context to the 80Days approach. Finally, the main results are summarized and further research activities are outlined.