gebhart/patrepeval huggingface dataset:
Practical forward secure sequential aggregate signatures (2008)

A forward secure sequential aggregate (FssAgg) signature scheme allows a signer to iteratively combine signatures generated in different time intervals - and with different keys - into a single constant-size signature. Such a signature offers forward security, storage/communication efficiency, as well as overall integrity of the signed messages. FssAgg schemes are therefore suitable for data-intensive applications on untrusted and/or unattended devices, e.g., logging systems. The first FssAgg signature scheme [21] is based on bilinear maps and is thus rather costly. In this paper, we propose two more practical FssAgg1 signature schemes. A FssAgg1 signature scheme is a special FssAgg signature scheme where exactly ONE message can be signed at each time interval and key update is invoked immediately after each signature generation. Both new schemes are derived from existing forward secure signature schemes. Unlike the scheme in [21], each new scheme has constant-size public and private keys, constant-size signatures as well as constant-time key update and signature generation complexity. We show how to apply proposed schemes in secure logging applications.
Algorithm Design and Applications (2015)

Introducing a NEW addition to our growing library of computer science titles,Algorithm Design and Applications, by Michael T. Goodrich & Roberto Tamassia! Algorithms is a course required for all computer science majors, with a strong focus on theoretical topics. Students enter the course after gaining hands-on experience with computers, and are expected to learn how algorithms can be applied to a variety of contexts. This new book integrates application with theory. Goodrich & Tamassia believe that the best way to teach algorithmic topics is to present them in a context that is motivated from applications to uses in society, computer games, computing industry, science, engineering, and the internet. The text teaches students about designing and using algorithms, illustrating connections between topics being taught and their potential applications, increasing engagement.
ChemInform Abstract: Synthesis of α‐Aminophosphonic Acids by Pd(0) Alkylation of Diethyl Aminomethylphosphonate Schiff Bases. (1989)

Abstract Imines such as (I), derived from diethyl aminomethanephosphonate, undergo Pd(0)‐catalyzed alkylation with the allylic esters (II) or (IV) or the carbonates (VII) to give the corresponding branched phosphonates, e.g. (III), (V) and (VI), or (VIII) and (IXc).
Myogenic Expression of Mesenchymal Stem Cells within Myotubes of <i>mdx</i> Mice <i>in Vitro</i> and <i>in Vivo</i> (1995)

The myogenic potential of bone marrow- and periosteum-derived mesenchymal stem cells (MSCs) was studied in vitro by coculture of MSCs of snj mice with myoblasts of newborn snj mice or 3-week-old mdx mice. MSCs were labeled with [(3)H]thymidine and cocultured with muscle precursor cells. At 5 different time points, the cocultures were harvested and prepared for autoradiography. Cocultures of MSCs and mdx mouse-derived myoblasts were immunostained for dystrophin before autoradiography. Autoradiographic grains were detected over isolated nuclei in myotubes, which stained positively with antidystrophin antibody. In vivo myogenic potential of MSCs was tested by direct injection into growing muscle of mdx mice. Equal numbers of nonmutant bone marrow-derived MSCs or myoblasts were injected separately into the tibialis anterior muscles of mdx mice. Muscle samples were harvested at 6, 8, and 10 weeks after injection, weighed, and stained with antidystrophin antibody. A small yet significant increase in muscle mass was observed in both the myoblast-injected (11% increase) and MSC-injected muscles (3%), as compared to controls. Muscle injected with myoblasts showed a remarkable conversion from dystrophin-negative to dystrophin-positive fibers (30-40%) in mdx mice injected with normal myoblasts, as previously reported by others. The frequency of dystrophin-positive fibers in mdx mouse muscle injected with marrow-derived MSCs was lower than that of the muscles injected with myoblasts, but was significantly higher than control muscles injected with medium. These results suggest that within the population of MSCs there are cells that are able to differentiate into skeletal muscle.
Recognition of Prostate and Melanoma Tumor Cells by Six-Transmembrane Epithelial Antigen of Prostate–Specific Helper T Lymphocytes in a Human Leukocyte Antigen Class II–Restricted Manner (2007)

The six-transmembrane epithelial antigen of prostate (STEAP) protein is an attractive candidate for T cell-based immunotherapy because it is overexpressed in prostate cancer and various other tumor types. Several peptide epitopes capable of stimulating CTLs that killed STEAP-expressing tumor cells have been described. Our goal was the identification of helper T lymphocyte (HTL) epitopes of STEAP for the optimization of T cell-based immunotherapies against STEAP-expressing malignancies. Candidate HTL epitopes for STEAP were predicted using in silico algorithms for HLA class II-binding peptides and were tested for their ability to elicit HTL responses by in vitro peptide vaccination of CD4 T lymphocytes from healthy individuals and prostate cancer patients. Two peptides (STEAP(102-116) and STEAP(192-206)) were effective in stimulating in vitro antitumor HTL responses in both normal individuals and prostate cancer patients. Notably, both STEAP HTL peptides behaved as promiscuous T-cell epitopes because they stimulated T cells in the context of more than one MHC class II allele. These newly described STEAP HTL epitopes could be of value for the design and optimization of T cell-based immunotherapy against STEAP-expressing tumors.
Altpaläolithische Holzgeräte aus Schöningen, Lkr. Helmstedt: Bedeutsame Funde zur Kulturentwicklung des frühen Menschen. (1999)

Seit 1983 wird die Erschliesung des Braunkohlentagebaues Schoningen in Ostniedersachsen durch grosflachige Rettungsgrabungen der Bodendenkmalpflege Hannover beglitet. In deren Verlauf konnten seit 1992 in den machtigen Quartardeckschichten des Tagebaues auch mehrere altpalaolithische Fundplatze aus der Zeit des Homo erectus entdeckt und teiluntersucht werden. Eine dieser Fundstellen - ein Wildpferd-Jagdlager- lieferter bisher u.a. acht holzerne Wurfspeere. Mit einem Alter von ca. 400 000 Jahren sind diese Gerate die bislang altesten vollstandig erhaltenen Jagdwaffen der Menschheit. Sie revidieren das gangige Weltbild von Urmenschen als einem marginalen Aasverwerter und belegen fur diese fruhe Zeit bereits systematische, planvolle Groswildjagd und sogar Jadspezialisierung sowie hohe Fertigkeiten in der Holzbearbeitung.
Superior vena cava syndrome associated with massive thrombosis: treatment with expandable wire stents. (1988)

Two patients with superior vena cava syndrome (SVCS) associated with massive thrombosis were treated by means of local thrombolytic therapy and placement of modified Gianturco expandable wire stents. Treatment resulted in complete resolution of the SVCS symptoms. The combination of local thrombolytic therapy and stent placement allows a more aggressive approach to treatment of SVCS and provides longer-term palliation of symptoms even for patients with later stages of the disease.
Thrombolysis: the logical approach for the treatment of vascular occlusions. (1992)

Thrombotic and thromboembolic occlusions of arteries and veins represent acute and often life threatening complications requiring immediate therapeutic intervention. The most important clinical manifestations of vascular occlusions are myocardial infarction, peripheral arterial occlusion, pulmonary embolism, deep vein thrombosis and ischemic stroke. The logical approach for the treatment in these indications is the early restoration of blood circulation in order to preserve the organ deprived from oxygen supply and to prevent chronic sequelae. Recanalization by surgical intervention is only possible in some indications and is restricted to special clinics. Thrombolysis induced by agents activating plasminogen imitates the physiologic way of dissolving an occlusive clot by shifting the balance of the hemostatic and fibrinolytic system towards fibrinolysis. Streptokinase was the first effective thrombolytic drug used in patients. In the first years of its usage the identification of the appropriate indication and the dosage and application regimens used were based on little pharmacological knowledge and lack of appropriate dose finding. This resulted in suboptimal therapeutic efficacy and severe bleeding. Development of advanced diagnostic methods, more appropriate dose and application regimens and the development of more specific fibrinolytic drugs like rt-PA led to a remarkable improvement of its benefit-risk ratio and made thrombolysis to a widely accepted form of therapy in thrombotic and thromboembolic diseases. Early restoration of blood flow however is only the starting point of a therapeutic strategy, aiming at minimizing the risk of recurrence.(ABSTRACT TRUNCATED AT 250 WORDS)
Hormone-Dependent Repression of the E2F-1 Gene by Thyroid Hormone Receptors (2003)

Thyroid hormone induces differentiation of many different tissues in mammals, birds, and amphibians. The different tissues all differentiate from proliferating precursor cells, and the normal cell cycle is suspended while cells undergo differentiation. We have investigated how thyroid hormone affects the expression of the E2F-1 protein, a key transcription factor that controls G1- to S-phase transition. We show that during thyroid hormone-induced differentiation of embryonic carcinoma cells and of oligodendrocyte precursor cells, the levels of E2F-1 mRNA and E2F-1 protein decrease. This is caused by the thyroid hormone receptor (TR) regulating the transcription of the E2F-1 gene. The TR binds directly to a negative thyroid hormone response element, called the Z-element, in the E2F-1 promoter. When bound, the TR activates transcription in the absence of ligand but represses transcription in the presence of ligand. In addition, liganded TR represses transcription of the S-phase-specific DNA polymerase alpha, thymidine kinase, and dihydropholate reductase genes. These results suggest that thyroid hormone-induced withdrawal from the cell cycle takes place through the repression of S-phase genes. We suggest that this is an initial and crucial step in thyroid hormone-induced differentiation of precursor cells.
Iron self-diffusion in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi mathvariant="normal">Fe</mml:mi><mml:mi mathvariant="normal">Zr</mml:mi><mml:mo>∕</mml:mo><mml:mmultiscripts><mml:mi mathvariant="normal">Fe</mml:mi><mml:mprescripts/><mml:none/><mml:mn>57</mml:mn></mml:mmultiscripts><mml:mi mathvariant="normal">Zr</mml:mi></mml:mrow></mml:math>multilayers measured by neutron reflectometry: Effect of applied compressive stress (2006)

Iron self-diffusion in nanocomposite FeZr alloy has been investigated using a neutron reflectometry technique as a function of applied compressive stress. A composite target of $\mathrm{Fe}+\mathrm{Zr}$ and $^{57}\mathrm{Fe}+\mathrm{Zr}$ was alternatively sputtered to deposit chemically homogeneous multilayer (CHM) structure ${[^{\mathit{\text{natural}}}\mathrm{Fe}_{75}{\mathrm{Zr}}_{25}∕^{57}\mathrm{Fe}_{57}{\mathrm{Zr}}_{25}]}_{10}$. The multilayers were deposited onto a bent Si wafer using a three-point bending device. Post-deposition, the bending of the substrate was released which results in an applied compressive stress on to the multilayer. In the as-deposited state, the alloy multilayer forms an amorphous phase, which crystallizes into a nanocomposite phase when heated at $373\phantom{\rule{0.3em}{0ex}}\mathrm{K}$. Bragg peaks due to isotopic contrast were observed from CHM, when measured by neutron reflectivity, while x-ray reflectivity showed a pattern corresponding to a single layer. Self-diffusion of iron was measured with the decay of the intensities at the Bragg peaks in the neutron reflectivity pattern after thermal annealing at different temperatures. It was found that the self-diffusion of iron slows down with an increase in the strength of applied compressive stress.
Quantenmechanische Behandlung des Lasers mit nichtresonanter Rückkopplung. III Berechnung des Frequenzspektrums (1969)

Abstract Neglecting intensity fluctuations of the radiation the mean photon number per mode, n λ, is calculated for a laser with nonresonant feedback in case of a homogenously as well as an inhomogenously broadened atomic line. The dependence of n λ on the frequency ωλ displays the frequency spectrum of the radiation which is found to be narrowed with respect to the spontaneous line. The linewidth, nevertheless, is much greater than in the case of a 1‐mode‐laser (with resonant feedback).
Neurocognitive signs in prodromal Huntington disease. (2010)

Neurocognitive tests are robust clinical indicators of the disease process prior to reaching criteria for motor diagnosis of HD.
Nb interaction with hydrogen plasma (2001)

A niobium membrane was immersed in hydrogen plasma and could be electrically biased to vary the energy of bombarding ions in the range of 1–200 eV. The fluxes of plasma driven absorption and permeation were almost entirely governed by incident suprathermal neutrals (mostly, thermal atoms), whose energy does not depend on membrane bias, but the ions of controllable energy do affect the neutral-induced permeation through modifying the membrane surface. At the zero bias a high temperature-independent plasma driven permeation (superpermeation) was observed alongside of an enhanced absorption. Bombardment by ions of an energy higher than 50 eV resulted in a sharp decrease of the plasma driven permeation/retention and in an acceleration of boundary processes of absorption/reemission of thermal molecules. At ion energies below 50 eV, the effect of ion bombardment on the plasma driven permeation and the kinetic coefficients of boundary processes were nonmonotonic in ion energy, having a maximum at ∼10 eV. Both an in situ doping with O of the bulk of Nb and a membrane temperature increase reduced the effects of ion bombardment to their complete disappearance. Responsible for that was the replenishment by means of surface segregation of an oxygen monolayer sputtered by ion bombardment.
항공사의 고객만족 교육프로그램이 객실승무원의 감정노동에 미치는 영향 (2015)

본 연구에서는 항공사의 고객만족 교육프로그램이 객실승무원의 감정노동에 미치는 영향에 대해 연구하였다. 항공사와 같은 서비스 기업에서 서비스 접점에 있는 객실승무원들의 고객에 대한 서비스는 고객만족을 가져오는데 매우 중요한 요소인데, 이러한 서비스를 수행하는 과정에서 감정노동이 수반되기 때문에 감정노동은 항공사의 성과에 영향을 주는 매우 중요한 부분이라고 생각했기 때문이다. 항공사에서 객실승무원들의 이러한 감정 관리를 하는 것은 기업의 성과와 경쟁력을 위해 매우 중요한 일이다. 따라서 다양한 통제 매커니즘을 활용하여 승무원들의 감정을 조직이 요구하는 방식대로 연출하게 하고 있다. 본 연구에서는 고객만족 교육프로그램을 매커니즘의 하나로 설정하였다. 감정노동은 서비스 접점에 있는 직원이 고객 응대 시 조직의 표현규칙에 따라 서비스를 수행하는 중에 수반되는 노력이며, 표면행동과 내면행동, 두 가지 하위차원이 있다. 표면행동은 실제 감정 변화의 노력이 아닌 외적으로 조직의 표현규칙을 표현하는 것이고, 내면행동은 내적인 감정 상태까지도 조직이 원하는 감정표현 규칙에 일치되는 방향으로 변화 시키려는 노력이다. 부정적인 측면이 많이 부각되어왔던 감정노동을, 내면행동을 통해 긍정적인 면을 재조명하고 고객만족 교육프로그램 요인들 중 내면행동에 유의한 영향을 미치는 요인을 찾아 항공사에서 승무원의 감정노동을 긍정적인 방향으로 유도하기 위한 전략을 모색하기 위함이 이 연구의 목적이다. 국내 A 항공사 승무원을 대상으로 250명에게 설문을 배포하여, 유효 응답한 207명의 설문내용을 가설검증을 위하여 실증분석 하였다. 분석결과, 고객만족 교육프로그램의 내용은 감정노동 중 표면행동에는 부(-)의 영향을, 내면행동에는 정(+)의 영향이 있는 것으로 나타났고 교육강사와 교육환경은 내면행동에 정(+)의 영향을 미치는 것으로 실증되었다. 그러나 고객만족 교육의 교육방법은 감정노동의 표면행동, 내면행동 모두에 유의미한 영향을 미치지 않는 것으로 나타났다. 이러한 연구결과를 통해 고객만족 교육프로그램의 교육내용은 직무와 연관성이 크고 기업의 목표를 잘 전달할 수 있으며, 피훈련자들에게 동기 부여할수 있는 내용으로 설계되어야 할 것이며, 교육강사의 경우 피훈련자에게 동기부여 하여 마음을 움직일수 있도록 유도하는 교육강사의 역할이 매우 중요하다는 것을 알 수 있었다. 또한 교육방법의 경우 고객만족 교육은 실무위주의 교육이므로 이론교육에 비해 좀 더 다양하고 영향력 있는 교육방법이 필요함을 시사하고 있다. 교육환경은 직무환경과 유사할수록 직원으로 하여금 조직이 원하는 표현규칙을 실현하기 위해 노력할 수 있는 분위기를 조성해 준다는 점에서 매우 중요한 시사점을 보여준다. 본 연구는 기존의 많은 연구에서와 같이 감정노동을 표면행동과 동일시하여 부정적이고 어쩔 수 없이 감수해야 하는 것으로만 보지 않고, 긍정적인 결과를 가져올 수 있는 내면행동에 초점을 맞추었으며, 고객만족 교육을 통해 이러한 내면행동으로 이끌 수 있다는 점을 제시했다. 또한 이를 통해 서비스 종사자에게 는 개인적인 성장을, 기업에는 성과를 가져올 수 있다는 점을 시사하고 있다.
Thermionic emission and Gaussian transport of holes in a GaAs/<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Al</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="normal">x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ga</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mi mathvariant="normal">−</mml:mi><mml:mi mathvariant="normal">x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math>As multiple-quantum-well structure (1988)

We present and test a modified thermionic emission model for time-resolved charge-carrier transport perpendicular to the layers of multiple quantum-well structures in an electric field. The predictions of the model on the nature (Gaussian transport) and the dynamics (transport times, field dependence of the mobility) of carrier transport agree favorably with our experiments performed for the case of holes and allow an accurate determination of the band offset.
An evaluation of intra-cage ventilation in three animal caging systems. (1989)

Although temperature and relative humidity have been quantitated and their effects on research data studied, few studies have measured the air turnover rates at cage level. We evaluated the air distribution and air turnover rates in unoccupied shoe-box mouse cages, filter-top covered cages and shoe-box mouse cages housed in a flexible film isolator by using discontinuous gas chromatography/mass spectrometry and smoke. Results showed that air turnover was most rapid in the unoccupied shoe-box mouse cage and slowest in the filter-top covered cage. Placing mice in the filter-top covered cage did not significantly improve the air turnover rate. Although filter-top covered cages reduce cage-to-cage transmission of disease, the poor airflow observed within these cages could lead to a buildup of gaseous pollutants that may adversely affect the animal's health.
The Sialidases of Clostridium perfringens Type D Strain CN3718 Differ in Their Properties and Sensitivities to Inhibitors (2013)

Clostridium perfringens causes histotoxic infections and diseases originating in animal or human intestines. A prolific toxin producer, this bacterium also produces numerous enzymes, including sialidases, that may facilitate infection. C. perfringens type D strain CN3718 carries genes encoding three sialidases, including two large secreted sialidases (named NanI and NanJ) and one small sialidase (named NanH) that has an intracellular location in log-phase cultures but is present in supernatants of death phase cultures. Using isogenic mutants of CN3718 that are capable of expressing only NanJ, NanI, or NanH, the current study characterized the properties and activities of each sialidase. The optimal temperature determined for NanJ or NanH enzymatic activity was 37°C or 43°C, respectively, while NanI activity increased until temperature reached 48°C. NanI activity was also the most resistant against higher temperatures. All three sialidases showed optimal activities at pH 5.5. Compared to NanJ or NanH, NanI contributed most to the sialidase activity in CN3718 culture supernatants, regardless of the substrate sialic acid linkage; NanI also released the most sialic acid from Caco-2 cells. Only NanI activity was enhanced by trypsin pretreatment and then only for substrates with an α-2,3- or α-2,6-sialic acid linkage. NanJ and NanI activities were more sensitive than NanH activity to two sialidase inhibitors (N-acetyl-2,3-dehydro-2-deoxyneuraminic acid and siastatin B). The activities of the three sialidases were affected differently by several metal ions. These results indicated that each C. perfringens sialidase has distinct properties, which may allow these enzymes to play different roles depending upon environmental conditions.
Digital camera resolution measurement using sinusoidal Siemens stars (2007)

The resolution of a digital camera is defined as its ability to reproduce fine detail in an image. To test this ability methods like the Slanted Edge SFR measurement developed by Burns and Williams1 and standardized in ISO 12233<sup>2</sup> are used. Since this method is - in terms of resolution measurements - only applicable to unsharpened and uncompressed data an additional method described in this paper had to be developed. This method is based on a Sinusoidal Siemens Star which is evaluated on a radius by radius or frequency by frequency basis. For the evaluation a freely available runtime program developed in MATLAB is used which creates the MTF of a camera system as the contrast over the frequency.
Calculation of the Properties of Reentrant Cylindrical Cavity Resonators (2007)

The lowest resonant frequencies of reentrant cylindrical cavity resonators are calculated using the method of moments to obtain upper and lower bounds. The accuracy and convergence of the results are investigated and the factors and shunt impedances calculated. A simple empirical assumption about the choice of basis functions leads to results that are of good accuracy and readily computed. The results obtained are compared with those of experiment and from calculations using MAFIA and Microwave Studio.
Monocyte aggregation and superoxide anion release in response to formyl-methionyl-leucyl-phenylalanine (FMLP) and platelet-activating factor (PAF). (1982)

Like the PMN, human peripheral blood monocytes were capable of aggregating in response to FMLP and PAF. Monocyte aggregation was dependent on glycolysis and the presence of divalent cations. Unlike the PMN, monocyte aggregation in response to FMLP was not accompanied by degranulation, nor was it potentiated by cytochalasin B. Furthermore, cytochalasin B and its cogenitor, dihydrocytochalasin B, inhibited aggregation in response to PAF. PAF and FMLP appeared to react with the monocyte at separate receptors because sequential challenge of the monocyte with the same agents failed to elicit further aggregation, whereas rechallenge with the alternative agent induced further aggregation. Because the monocyte will aggregate to chemotactic agents in vitro, it is likely that the cell will be affected by these agents in vivo, which could lead to leukoembolization of circulating monocytes.
Photoluminescence properties of a natural fluorite. (2000)

Photoluminescence properties of a natural fluorite from China are investigated at temperatures of 10, 80 and 300 K. The color of the fluorite is green under the daylight and it emits bluish violet fluorescence under UV light. The band peak (423 nm) at room temperature and the vibronic structure at low temperatures show that the bluish violet fluorescence originates from Eu2+ ion in the fluorite. In the excitation spectrum obtained by monitoring the bluish violet fluorescence, not only the Eu2+ band but the Ce3+ band are observed as broad bands. They are attributed to the f-d electronic transitions in Eu2+ and Ce3+. It was interpreted that the excitation processes of the bluish violet fluorescence are due to the direct excitation of the Eu2+ ion and the energy transfer from Ce3+ to Eu2+ in fluorite. The abundance of rare-earth impurities in the fluorite was analyzed by inductively coupled plasma-mass spectrometry (ICP-MS) after the treatment with the cation-exchange column. Relationship between the photoluminescence and rare-earth impurities is discussed.