gebhart/patrepeval huggingface dataset:
Blooming Artifact Reduction in Coronary Artery Calcification by A New De-blooming Algorithm: Initial Study (2018)

The aim of this study was to investigate the use of de-blooming algorithm in coronary CT angiography (CCTA) for optimal evaluation of calcified plaques. Calcified plaques were simulated on a coronary vessel phantom and a cardiac motion phantom. Two convolution kernels, standard (STND) and high-definition standard (HD STND), were used for imaging reconstruction. A dedicated de-blooming algorithm was used for imaging processing. We found a smaller bias towards measurement of stenosis using the de-blooming algorithm (STND: bias 24.6% vs 15.0%, range 10.2% to 39.0% vs 4.0% to 25.9%; HD STND: bias 17.9% vs 11.0%, range 8.9% to 30.6% vs 0.5% to 21.5%). With use of de-blooming algorithm, specificity for diagnosing significant stenosis increased from 45.8% to 75.0% (STND), from 62.5% to 83.3% (HD STND); while positive predictive value (PPV) increased from 69.8% to 83.3% (STND), from 76.9% to 88.2% (HD STND). In the patient group, reduction in calcification volume was 48.1 ± 10.3%, reduction in coronary diameter stenosis over calcified plaque was 52.4 ± 24.2%. Our results suggest that the novel de-blooming algorithm could effectively decrease the blooming artifacts caused by coronary calcified plaques, and consequently improve diagnostic accuracy of CCTA in assessing coronary stenosis.
Active Learning for Word Sense Disambiguation with Methods for Addressing the Class Imbalance Problem (2007)

In this paper, we analyze the effect of resampling techniques, including undersampling and over-sampling used in active learning for word sense disambiguation (WSD). Experimental results show that under-sampling causes negative effects on active learning, but over-sampling is a relatively good choice. To alleviate the withinclass imbalance problem of over-sampling, we propose a bootstrap-based oversampling (BootOS) method that works better than ordinary over-sampling in active learning for WSD. Finally, we investigate when to stop active learning, and adopt two strategies, max-confidence and min-error, as stopping conditions for active learning. According to experimental results, we suggest a prediction solution by considering max-confidence as the upper bound and min-error as the lower bound for stopping conditions. 1
Vascular Endothelial Growth Factor Drives Autocrine Epithelial Cell Proliferation and Survival in Chronic Rhinosinusitis with Nasal Polyposis (2009)

These data demonstrate that VEGF is a novel biomarker for chronic rhinosinusitis with hyperplastic sinonasal polyposis that functions in an autocrine feed-forward manner to promote nasal epithelial cell growth and to inhibit apoptosis. These findings implicate a previously unrecognized and novel role of VEGF functioning through neuropilin-1 on nonneoplastic primary human airway epithelial cells, to amplify cell growth, contributing to exuberant hyperplastic polyposis.
Phase Calibration of On-Chip Optical Phased Arrays via Interference Technique (2020)

Optical phased arrays (OPAs) are promising in various applications owing to their excellent beam steering performance but suffer from the random initial phases ruining the beam patterns. In this work, an interference-based calibration method to align the random phases for OPA operations is proposed. Briefly, the phase differences are directly extracted from the interference fringes and used to build up the phase map. The feasibility and effectiveness of the proposed method were verified from an 8 × 8 OPA chip, in which the side-lobe suppression ratio of 10.1 dB was achieved. The proposed method can be utilized as a supplement of conventional calibration algorithms to reduce requirements for the sensitivity of the feedback system and avoid local optima, thus providing practical assistance for many OPA applications.
Lazy TLB consistency for large-scale multiprocessors (2002)

A memory system's performance heavily depends on the efficiency of a translation lookaside buffer (TLB), a cache for fast address translation. Recent trends towards multiprocessing as well as modular software structures impose more stress on TLBs, since consistency among multiple TLBs should be maintained. However, previous TLB consistency schemes do not seem suitable for large-scale multiprocessors, because they require interprocessor interrupts, which are extremely harmful to the overall system performance. In this paper, we propose a lazy TLB scheme for large-scale multiprocessors. By exploring the potential of lazy release consistency, the scheme postpones the TLB synchronization until the time of an acquistion access to the shared data. This scheme allows a processor to invalidate remote TLBs asynchronously, and eliminates the need for interprocessor interrupts. Simulation results show that the lazy TLB scheme is very efficient for large-scale multiprocessors.
Instant profiling: Instrumentation sampling for profiling datacenter applications (2013)

Profile-guided optimization possesses huge potential to save costs for datacenters. Hardware performance monitoring units enable profiling with negligible overhead and they have been proven to be effective to help programmers find code regions to optimize by monitoring datacenter applications continuously on live traffic. However, these hardware features are inflexible and often buggy, limiting the types of data that can be gathered. Instrumentation-based profiling can complement or replace hardware functionality by providing more flexible and targeted information gathering. Unfortunately, the overhead of existing instrumentation mechanisms prevents their use in production runs. In order to be used in datacenters, we need a profiling mechanism to impose overheads of less than a few percent, in terms of both throughput and latency, while still generating meaningful profile data. This paper presents instant profiling, an instrumentation sampling technique using dynamic binary translation. Instead of instrumenting the entire execution, instant profiling periodically interleaves native execution and instrumented execution according to configurable profiling duration and frequency parameters. It further reduces the latency degradation of initial profiling phases by pre-populating a software code cache. We evaluate the performance and effectiveness of this new profiling technique on the SPEC CINT2006 benchmark suite and two datacenter application benchmarks. We show that it is well-suited for deployment to datacenters by incurring less than 6% slowdown and 3% computational overhead on average.
An extensible kernel object management system (1991)

article An extensible kernel object management system Share on Authors: Rahim Yaseen Database Systems Research and Development Center, Department of Computer and Information Sciences, Department of Electrical Engineering, CSE 470, University of Florida, Gainesville, FL Database Systems Research and Development Center, Department of Computer and Information Sciences, Department of Electrical Engineering, CSE 470, University of Florida, Gainesville, FLView Profile , Stanley Y. W. Su Database Systems Research and Development Center, Department of Computer and Information Sciences, Department of Electrical Engineering, CSE 470, University of Florida, Gainesville, FL Database Systems Research and Development Center, Department of Computer and Information Sciences, Department of Electrical Engineering, CSE 470, University of Florida, Gainesville, FLView Profile , Herman Lam Database Systems Research and Development Center, Department of Computer and Information Sciences, Department of Electrical Engineering, CSE 470, University of Florida, Gainesville, FL Database Systems Research and Development Center, Department of Computer and Information Sciences, Department of Electrical Engineering, CSE 470, University of Florida, Gainesville, FLView Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 26Issue 11Nov. 1991 pp 247–263https://doi.org/10.1145/118014.117973Online:01 November 1991Publication History 11citation325DownloadsMetricsTotal Citations11Total Downloads325Last 12 Months4Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Decorrelation for adaptive beamforming applied to arbitrarily sampled spherical microphone arrays (2011)

Correlated signals lead to signal cancellation in adaptive beamformers applied to microphone arrays. This is commonly counteracted by spatial smoothing. Unfortunately, spatial smoothing can only be used with array geometries consisting of identical, shifted subarrays, making it unsuitable for spherical arrays in general. We suggest a transformation that makes spatial smoothing applicable to any well-sampled spherical array, and we show results for the case of Minimum Variance Distortionless Response (MVDR) beamforming.
ChemInform Abstract: Studies Toward the Total Synthesis of Sarsolilide A: Preparation of the Proper Precursor for the Macrocyclization. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Emotion Recognition In The Wild Challenge 2014 (2014)

The Second Emotion Recognition In The Wild Challenge (EmotiW) 2014 consists of an audio-video based emotion classification challenge, which mimics the real-world conditions. Traditionally, emotion recognition has been performed on data captured in constrained lab-controlled like environment. While this data was a good starting point, such lab controlled data poorly represents the environment and conditions faced in real-world situations. With the exponential increase in the number of video clips being uploaded online, it is worthwhile to explore the performance of emotion recognition methods that work `in the wild'. The goal of this Grand Challenge is to carry forward the common platform defined during EmotiW 2013, for evaluation of emotion recognition methods in real-world conditions. The database in the 2014 challenge is the Acted Facial Expression In Wild (AFEW) 4.0, which has been collected from movies showing close-to-real-world conditions. The paper describes the data partitions, the baseline method and the experimental protocol.
Enzyme-Linked Immunosorbent Assay for Detection of Immunoglobulin M Antibodies Against <i>Toxoplasma gondii</i> (1980)

A new principle that uses anti-immunoglobulin M-coated polystyrene microtiter plates for the detection of immunoglobulin M antibodies against Toxoplasma gondii by an enzyme-linked immunosorbent assay was developed.
Pulsed Electric Field Effects on Biological Cells (2001)

Abstract : A new type of field-cell interaction, Intracellular Electromanipulation, by means of nonthermal, wideband electromagnetic radiation is being studied. It is based on capacitive coupling to cell substructures, and has therefore the potential to affect transport processes across subcellular membranes. This was verified experimentally by applying electrical pulses of 60 nanosecond duration, with electric field amplitudes of 50kV/cm to human eosinophils in vitro. Besides causing poration of intracellular membranes without disrupting the outer cell membrane, sub-microsecond pulses were found to induce apoptosis in cells.
Intracellular levels of glycerol necessary for initiation of growth under salt-stressed conditions in a salt-tolerant yeast,<i>Zygosaccharomyces rouxii</i> (1988)

The relationship between the intracellular concentration of glycerol and the initiation of growth under salt-stressed conditions in the salt-tolerant yeast Zygosaccharomyces rouxii was studied. The results demonstrated that the accumulation of a definite intracellular concentration of glycerol is required prior to the initiation of growth under NaCl-stressed conditions. The initiation of growth in 3 M and 3.5 M NaCl media started at low intracellular concentrations such as 0.51 and 1.17 mol/l cell volume. Similar results were obtained under KCl- and MgCl2-stressed conditions. However, Z. rouxii was unable to grow under LiCl-stressed conditions, though it accumulated glycerol to the level required for the initiation of growth.
A fully-integrated semicircular canal processor for an implantable vestibular prosthesis (2008)

This paper presents a fully-integrated semicircular canal processor for an implantable vestibular prosthesis. The system includes the entire processing chain required from the microsensor interface, through the required biomimetic transfer characteristics, to a current-mode signal, suitable for feeding the stimulator. Using a switched-capacitor implementation, the circuit is inherently tunable, whilst maintaining low power operation and overcoming the need for off-chip components. The entire system core occupies an area of 0.23 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in a commercially available 0.35 mum CMOS technology.
Scaffolds for stem cells (2006)

Today, most people know at least something about stem cells. Embryonic stem cells enjoy regular mentions in news programs and magazines, probably because of the controversial way in which they are generated but also because of their huge potential in medicine. Here we distinguish between and define types of stem cells, discuss techniques used so far to create various cells and tissues from stem cells, and discuss how three-dimensional supports and stem cells have been and should be used to encourage the development of functional replacement tissue.
Metformin for the Treatment of the Polycystic Ovary Syndrome (2008)

A 23-year-old woman with the polycystic ovary syndrome presents for evaluation and possible treatment. She has a family history of diabetes, is obese, and has impaired glucose tolerance. Metformin therapy is recommended. Metformin increases insulin sensitivity and may reduce the risk of diabetes. In the polycystic ovary syndrome, long-term metformin treatment may increase ovulation, improve menstrual cyclicity, and reduce serum androgen levels.
Nitazoxanide for persistent diarrhoea in Zambian acquired immune deficiency syndrome patients: a randomized‐controlled trial (2005)

Nitazoxanide given orally for 14 days was associated with clinical improvement in Zambian acquired immune deficiency syndrome patients with diarrhoea, especially those with very low CD4 counts.
1105 – Long-term Efficacy Of Nalmefene As-needed In Alcohol Dependent Patients With High Drinking Risk Levels: Results Of a Subgroup Analysis (2013)

Introduction We describe the efficacy and safety of as-needed use of nalmefene in the subgroup of patients with a high drinking risk level (DRL; men:>60g/day; women:>40g/day); i.e. a group of patients with a great unmet medical need for treatment. Objectives To evaluate the 1 year efficacy and safety of as-needed use of nalmefene 18mg versus placebo in a subgroup of alcohol dependent patients with high DRL from a randomised controlled trial [NCT00811941]. Methods All patients received a motivational and adherence-enhancing intervention (BRENDA) in combination with either nalmefene or placebo. Number of heavy drinking days (HDDs) and total alcohol consumption (TAC) were measured using the Timeline Follow-back method. Additionally, data on clinical improvement, liver function and safety were collected throughout the study. Results The study population consisted of 187 patients: placebo N=42; nalmefene N=145 (mean age 46.2±11.9 years; 78% men; mean HDDs 19±6.3/month; mean TAC 101±45.0 g/day). Mean number of HDDs decreased to 7 days/month and mean TAC decreased to 33g/day at 1 year in the nalmefene group. At 1 year, there was a superior effect of nalmefene compared to placebo in reducing the number of HDDs (-3.6 [95% CI:-6.5;-0.7]; p=0.0164) and TAC -17.3 [-30.9;-3.8]; p=0.0129). Improvements in clinical status and in liver enzymes from baseline were larger in the nalmefene compared to the placebo group. Adverse events and adverse events leading to dropout were more common with nalmefene than placebo. Conclusions As-needed nalmefene was efficacious in reducing alcohol consumption in patients with high risk for alcoholrelated harm.
Neural network based self-tuning control of a switched reluctance motor drive to maximize torque per ampere (2002)

Online self-tuning control is essential as optimize the performance of a switched reluctance motor (SRM) drive in the presence of parameter variations. This paper introduces an advanced adaptive neural network (NN) based control scheme to maximize torque per ampere in the low speed region. The proposed control technique utilizes a heuristic search method to find the change in the optimal excitation instances in case of parameter variations. Based on the results of this heuristic search, the NN employs incremental learning to adapt its network weights. Computer simulations are performed to verify the applicability of the proposed algorithm. Experimental results are provided to demonstrate the working of the self-tuning controller.
Rapid and Sensitive Screening of <i>N-</i>Glycans as 9-Fluorenylmethyl Derivatives by High-Performance Liquid Chromatography:  A Method Which Can Recover Free Oligosaccharides after Analysis (2005)

There are a large number of labeling methods for asparagine-type oligosaccharides with fluorogenic and chromophoric reagents. We have to choose the most appropriate labeling method based on the purposes such as mass spectrometry, high-performance liquid chromatography and capillary electrophoresis. Asparagine-type glycans are released from core proteins as N-glycosylamine at the initial step of the releasing reaction when glycoamidase F is employed as the enzyme. The N-glycosylamine-type oligosaccharides thus released by the enzyme are subjected to hydrolysis or mutarotation to form free-form oligosaccharides. In the detailed studies on the enzyme reaction, we found a condition in which the released N-glycosylamine-type oligosaccharides were exclusively present at least during the course of enzyme reaction, and developed a method for in situ derivatization of the glycosylamine-type oligosaccharides with 9-fluorenylmethyl chloroformate (Fmoc-Cl). The Fmoc labeled sialo- and asialo- (or high-mannose and hybrid) oligosaccharides were successfully analyzed on an amine-bonded polymer column and amide-silica column, respectively. The present method showed approximately 5 times higher sensitivities than that using 2-aminobenzoic acid (2-AA). The separation profile was similar to that observed using 2-AA method as examined by the analyses of carbohydrate chains derived from several glycoproteins including complex-type, high-mannose type and hybrid type of N-linked oligosaccharides. The labeled oligosaccharides were stable at least for several months when stored at -20 degrees C. Furthermore, it should be emphasized that the Fmoc-derivatized oligosaccharides could be easily recovered as free reducing oligosaccharides simply by incubation with morpholine in dimethylformamide solution. We obtained a pure triantennary oligosaccharide with 3 sialic acid residues as a free reducing form from fetuin in good yield after isolation of the corresponding Fmoc oligosaccharide followed by removing reaction of the Fmoc group. The proposed method will be useful for preparation of free oligosaccharides as standard samples at pmol-nmol scale from commercially available glycoproteins.
Mechanical factors favoring release from fouling release coatings (2000)

For some twenty years the marine coatings industry has been intrigued by polymer surfaces with low adhesion to other materials, especially to the biological glues used by marine organisms. Polymers with fouling release surfaces have been made from sundry materials, and their resistance to marine fouling in both static and dynamic tests has been evaluated in the world's oceans. Although the polymer surface property most frequently correlated with bioadhesion is its critical surface tension (γ(?)), resistance to fouling is also influenced by other bulk and surface properties of the polymer. This paper reviews the types of bonding associated with polymeric materials used in fouling resistant coatings, describes the removal process in terms of fracture mechanics, and discusses the importance of surface energy, elastic modulus and coating thickness in the release of biofoulants.
Structural and electrical properties of films sputtered from a Pt cathode in argon−oxygen mixtures (1975)

Films have been deposited on glass and polycrystalline alumina substrates by reactive dc sputtering of platinum in oxygen−argon mixtures. The films properties depend on the oxygen/argon ratio and on the discharge parameters. Whereas the resistivity was 25 μΩ cm in an argon discharge at 5 kV, it was higher than 1.5 Ω cm in an oxygen discharge at 2 kV. Corresponding changes were obtained in the temperature coefficient of resistance; values from +2000 to −25000 ppm/°C were measured. As the resistivity increased, the film density decreased from 21.5 to 15.5 g/cm3. These results are interpreted in terms of a cermetlike film structure consisting of mixtures of Pt and oxides of platinum. X−ray and electron diffraction analysis confirms the presence of a phase isostructural with PdO which is considered to be PtO. This phase decomposes to Pt on heating in air at temperatures above 600 °C and thermogravimetric analysis showed that the film composition changed from Pt to PtO1.3 as the temperature coefficient of resistance changed from +2000 to −11000 ppm/°C. It is porposed that an amorphous PtO2 phase is also present in these films and ESCA spectra have confirmed the presence of Pt, PtO, and PtO2. Analysis of the sputtering discharge characteristics and changes in the gas composition during sputtering are consistent with gettering of oxygen by the sputtered Pt.
Liposomes as vehicle for allergen presentation in the immunotherapy of allergic diseases (1991)

Liposomes are non-toxic, biodegradable and weakly immunogenic lipid vesicles which can be used as immunomodulating agents. In the present study, multilamellar vesicles (MLV) and small unilamellar vesicles (SUV) were used to incorporate an allergenic protein from Artemisia scoparia pollen. MLV incorporated more allergenic protein than SUV. To assess the immunomodulating effect of allergen entrapped in liposomes, Swiss strain mice (made IgE responders) were injected with either free allergen or liposome-entrapped allergen (LEA) and their immune response was measured in terms of specific IgG and specific IgE levels. Results indicated that specific IgE response was significantly lower in mice injected LEA (P less than 0.02) than in mice injected free allergenic protein. Although specific IgG response was higher in mice injected LEA, there was no statistically significant difference between the two groups. Potential use of liposomes as non-immunogenic biocompatible vehicle for antigen presentation in immunotherapy will be discussed.