gebhart/patrepeval huggingface dataset:
Scheduling of direct load control to minimize load reduction for a utility suffering from generation shortage (1993)

This paper adopts the method of dynamic programming to optimally determine the schedule of the direct load control, but its objective function is to minimize the amount of load reduction with appropriate constraints. This approach is intended to solve the chronic problem of severe power shortage in the summer for the Taiwan Power Company (Taipower or TPC). This scheduling scheme is to reduce the resulting inconvenience to customers as well as the effects to the total income from electricity sales to the minimum under the particular management conditions the TPC finds itself in.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Hepatitis C Virus Glycoprotein E2 Contains a Membrane-proximal Heptad Repeat Sequence That Is Essential for E1E2 Glycoprotein Heterodimerization and Viral Entry (2004)

The E1 and E2 glycoproteins of hepatitis C virus form a noncovalently associated heterodimer that mediates viral entry. Glycoprotein E2 comprises a receptor-binding domain (residues 384-661) that is connected to the transmembrane domain (residues 716-746) via a highly conserved sequence containing a hydrophobic heptad repeat (residues 675-699). Alanine- and proline-scanning mutagenesis of the E2 heptad repeat revealed that Leu675, Ser678, Leu689, and Leu692 are important for E1E2 heterodimerization. Furthermore, Pro and Ala substitution of all but one heptad repeat residue (Ser678) blocked the entry of E1E2-HIV-1 pseudotypes into Huh7 cells, irrespective of an effect on heterodimerization. Two conserved prolines (Pro676 and Pro683), occupying consecutive b positions of the heptad, were not required for E1E2 heterodimerization; however, Pro683 was critical for viral entry. Thus, disruption of the predicted alpha-helical structure by proline at position 683 is important for E2 function. The inability of mutants to mediate viral entry was not explained by a loss of receptor binding function, because all mutants were able to interact with a recombinant form of the CD81 large extracellular loop. Chimeras formed between the E1 and E2 ectodomains and the transmembrane domains of flavivirus prM and E glycoproteins, respectively, were able to heterodimerize, although with lower efficiency in comparison with wild type E1E2. The heptad repeat of E2 therefore requires the native transmembrane domain for full heterodimerization and viral entry function. Our data indicate that the membraneproximal heptad repeat of E2 is functionally homologous to the stem of flavivirus E glycoproteins. We propose that E2 has mechanistic features in common with class II fusion proteins.
Sequence conservation in the C-terminal region of spider silk proteins (Spidroin) from Nephila clavipes (Tetragnathidae) and Araneus bicentenarius (Araneidae). (1994)

The polymerase chain reaction (PCR) has been used to amplify the portion of the Spidroin 1 gene that codes for the C-terminal part of the silk protein of the spider Nephila clavipes. Along with some substitution mutations of minor consequence, the PCR-derived sequence reveals an additional base missing from the previously published Nephila Spidroin 1 sequence. Comparison of the PCR-derived sequence with the equivalent region of Spidroin 2 indicates that the insertion of this single base results in greatly increased similarity in the resulting amino acid sequences of Spidroin 1 and Spidroin 2 (75% over 97 amino acids). The same PCR primers also amplified a fragment of the same length from Araneus bicentenarius. This sequence is also very similar to Spidroin 1 of Nephila (71% over 238 bases excluding the PCR primers, which translates into 76% over 79 amino acids).
IoT-Based Smart Irrigation Systems: An Overview on the Recent Trends on Sensors and IoT Systems for Irrigation in Precision Agriculture (2020)

Water management is paramount in countries with water scarcity. This also affects agriculture, as a large amount of water is dedicated to that use. The possible consequences of global warming lead to the consideration of creating water adaptation measures to ensure the availability of water for food production and consumption. Thus, studies aimed at saving water usage in the irrigation process have increased over the years. Typical commercial sensors for agriculture irrigation systems are very expensive, making it impossible for smaller farmers to implement this type of system. However, manufacturers are currently offering low-cost sensors that can be connected to nodes to implement affordable systems for irrigation management and agriculture monitoring. Due to the recent advances in IoT and WSN technologies that can be applied in the development of these systems, we present a survey aimed at summarizing the current state of the art regarding smart irrigation systems. We determine the parameters that are monitored in irrigation systems regarding water quantity and quality, soil characteristics and weather conditions. We provide an overview of the most utilized nodes and wireless technologies. Lastly, we will discuss the challenges and the best practices for the implementation of sensor-based irrigation systems.
The Reaction of AL with Vitreous Silica (1977)

The solid state chemical reaction between aluminum films and vitreous silicon dioxide substrates is reported. This reaction where aluminum reduces silicon dioxide to form elemental silicon and aluminum oxide is extensively used in the semiconductor industry to remove native SiO2 thin layers at ohmic contacts and to promote adhesion of aluminum to silica. Sorbed water vapor on silica is shown to interfere with the reaction reducing the adherence of aluminum to silica. The rate of penetration of the reaction into silicon dioxide was found to follow an Arrhenius relationship with an activation energy of 2.562 eV.
Estimation with lossy measurements: jump estimators for jump systems (2003)

In this paper, we consider estimation with lossy measurements. This problem can arise when measurements are communicated over wireless channels. We model the plant/measurement loss process as a Markovian jump linear system. While the time-varying Kalman estimator (TVKE) is known to be optimal, we introduce a simpler design, termed a jump linear estimator (JLE), to cope with losses. A JLE has predictor/corrector form, but at each time selects a corrector gain from a finite set of precalculated gains. The motivation for the JLE is twofold. The computational burden of the JLE is less than that of the TVKE and the estimation errors expected when using JLE provide an upper bound for those expected when using TVKE. We then introduce a special class of JLE, termed finite loss history estimators (FLHE), which uses a canonical gain selection logic. A notion of optimality for the FLHE is defined and an optimal synthesis method is given. The proposed design method is compared to TVKE in a simulation study.
The President's Column Communications (1984)

Presents the President's message for this issue of the publication.
Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms (2011)

Alternatively activated macrophages, generated in a T-helper 2 environment, have demonstrated roles in wound repair and tissue remodeling in addition to being charged with immune tasks. Because the hydrolytic chemistries of the phagosomal lumen are central to many of these functions, we investigated their modification after alternative activation with IL-4 and IL-13. Most significantly, we found striking up-regulation of the proteolytic levels within the phagosome of IL-4-activated macrophages. Two synergistic mechanisms were determined to underlie this up-regulation. First, IL-4-activated macrophages displayed increased expression of cathepsin S and L, providing greater proteolytic machinery to the phagosome despite unchanged rates of lysosomal contribution. Secondly, decreased phagosomal NADPH oxidase (NOX2) activity, at least partially resulting from decreased expression of the NOX2 subunit gp91(phox), resulted in a more reductive lumenal microenvironment, which in turn, enhanced activities of local cysteine cathepsins. Decreased NOX2 activity additionally increased the phagosome's ability to reduce disulfides, further enhancing the efficiency of the macrophage to degrade proteins containing disulfide bonds. Together, these changes initiated by IL-4 act synergistically to rapidly and dramatically enhance the macrophage's ability to degrade phagocytosed protein, which, we reason, better equips this cell for its roles in wound repair and tissue remodeling.
α‐Fetoprotein positively regulates cytochrome <i>c</i>‐mediated caspase activation and apoptosome complex formation (2003)

Previous results have shown that the oncoembryonic marker alpha-fetoprotein (AFP) is able to induce apoptosis in tumor cells through activation of caspase 3, bypassing Fas-dependent and tumor necrosis factor receptor-dependent signaling. In this study we further investigate the molecular interactions involved in the AFP-mediated signaling of apoptosis. We show that AFP treatment of tumor cells is accompanied by cytosolic translocation of mitochondrial cytochrome c. In a cell-free system, AFP mediates processing and activation of caspases 3 and 9 by synergistic enhancement of the low-dose cytochrome c-mediated signals. AFP was unable to regulate activity of caspase 3 in cell extracts depleted of cytochrome c or caspase 9. Using high-resolution chromatography, we show that AFP positively regulates cytochrome c/dATP-mediated apoptosome complex formation, enhances recruitment of caspases and Apaf-1 into the complex, and stimulates release of the active caspases 3 and 9 from the apoptosome. By using a direct protein-protein interaction assay, we show that pure human AFP almost completely disrupts the association between processed caspases 3 and 9 and the cellular inhibitor of apoptosis protein (cIAP-2), demonstrating its release from the complex. Our data suggest that AFP may regulate cell death by displacing cIAP-2 from the apoptosome, resulting in promotion of caspase 3 activation and its release from the complex.
Classic Hand Tools (1999)

Before the machine age, all woodworking was done with handtools. Even now with machinery available for many woodworking operations, some tasks are more easily and efficiently accomplished with handtools. This book celebrates the great heritage of traditional tools while providing practical information on how to integrate their use in one's everyday woodworking. * workshops, benches & clamps * marking & measuring tools * striking tools * * chisels, gouges & drawknives * planes * scrapers, files & rasps * boring tools * * saws * making & restoring hand tools * buying used hand tools *
<i>Candida</i>cell wall mannan in the vagina and its association with the signs and symptoms of vaginal candidosis (1991)

Measurement of Candida cell wall polysaccharide (mannan) with an enzyme-linked immunosorbent assay (ELISA) was evaluated as an alternative to viable counting for the enumeration of yeast cell numbers in the human vagina. A statistically significant association was found between mannan levels and the number of colony forming units in vaginal washings collected from 40 women infected with Candida albicans (r = 0.81), indicating the accuracy of mannan levels in reflecting yeast cell load in vulvo-vaginal candidosis. Subsequent comparisons revealed a significant association between mannan levels and clinical signs in the vagina, so reflecting the importance of vulvitis and vaginitis as clinical markers for determining the severity of infection. No association was found between yeast load and the clinical symptoms, indicating the high degree of patient subjectivity. Estimation of mannan levels could be developed and used for the rapid laboratory investigation of chronic vulvo-vaginal candidosis.
전남 구례지역의 백악기층에 나타나는 화산암에 대한 K-Ar 연대 (2015)

구례지역에서 공룡알과 공룡뼈가 보고된 백악기 토금층의 퇴적시기와 공룡의 활동시기를 밝히기 위하여 그 층의 하부와 상부에 해당하는 화산암류에 대하여 K-Ar법 절대연대측정 연구를 수행했다. 토금층의 하부에 분포하는 금정리역암층에 포함된 화산암역을 대상으로 6개의 시료에 대하여 K-Ar 전암연대 측정을 실시하였으며, 그 결과 전기 백악기의 앞티안(118.3±2.3 Ma), 알비안(103.6±2.0, 102.5±2.0, 99.9±1.9 Ma)에 속한다. 토금층을 덮는 안산암과 반상안산암에 대하여 동일 조건으로 절대연대를 측정하였으며 그 결과는 후기 백악기의 캄파니안(83.9±1.6, 74.2±1.5 Ma)에 속한다. 야외증거와 절대연대측정 결과를 근거로 토금층의 퇴적시기와 공룡의 활동시기는 84-100 Ma 사이이다. 이 결과는 공룡알을 포함하는 보성 선소층의 퇴적시기(81 Ma)와 공룡, 익룡 및 물갈퀴 새발자국을 포함하는 해남 우항리층의 퇴적시기(79-81 Ma), 압해도지역에 분포하는 수각류 공룡알둥지의 형성시기(77-83 Ma)에 비교하면 다소 오래되었을 가능성을 시사한다.
UV tuning of coupling in twin-core optical fibres (1994)

The isolation of a wavelength-demultiplexing twin-core fibre with nominally identical cores is improved from 7 dB to 26 dB by increasing the refractive index of one core. Tuning relaxes the fabrication tolerances necessary for ≥ 20 dB isolation between channels, enhancing the feasibility of using twin-core fibres for demultiplexing 1.3 and 1.55 µm signals in communications systems.
A Synthesis of Aldosterone Acetate<sup>1</sup> (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Synthesis of Aldosterone Acetate1D. H. R. Barton and J. M. BeatonCite this: J. Am. Chem. Soc. 1961, 83, 19, 4083–4089Publication Date (Print):October 1, 1961Publication History Published online1 May 2002Published inissue 1 October 1961https://pubs.acs.org/doi/10.1021/ja01480a031https://doi.org/10.1021/ja01480a031research-articleACS PublicationsRequest reuse permissionsArticle Views989Altmetric-Citations141LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Increased levels of albumin in bronchial washing fluid of patients with bronchial carcinoma. Could albumin be considered as a tumor marker? (2004)

The aim of this study was to evaluate the significance of albumin in bronchial washing fluid (BWF) and its relationship to three tumor markers (CEA, CA 19-9 and NSE).Serum and BWF samples were collected in a group of 60 patients. Albumin and tumor markers in the BWF and serum of three groups: a control group (CG), a chronic bronchitis group (CBG) and a lung cancer group (CaG), were analyzed in a prospective cross-sectional study. The diagnostic yields of the tests in each environment (serum and BWF) were evaluated by using as cutoff points the values of the corresponding 90th percentile of CG and CBG taken together.A significant difference in albumin level (p < 0.001) was noted in the BWF of patients with cancer compared with the other two groups. In addition, a significant difference in CEA level (p < 0.001) was observed in the serum of cancer patients compared with the other two groups. The cutoff values for CEA in serum and albumin in BWF were 2.20 ng/mL and 2.00 g/dL, respectively. The areas under the corresponding ROC curves were 93% and 97%. Combination of CEA-serum and albumin-BWF by logistic regression analysis increased their diagnostic value.Measurement of albumin levels in BWF could be a useful additional diagnostic tool to differentiate malignant from non-malignant lung diseases. Moreover, the combined measurement of CEA in serum and albumin in BWF could be of aid in the follow-up of lung cancer patients.
Object-based texture coding of moving video in MPEG-4 (1999)

This paper describes some of the most promising segment-based coding techniques which have been investigated in the course of the MPEG-4 standardization process. Padding methods aim at extending arbitrarily shaped image segments to a regular block grid such that common hybrid block-based coding techniques can be applied. A simple and efficient padding technique employing low-pass extrapolation is outlined which yields a signal extension with high energy concentration in the low-frequency area. Simulations indicate that this method is well suited for block-based video coding, and clearly outperforms other low-complexity extrapolation methods with respect to coding efficiency. In contrast to padding techniques, shape-adaptive methods take advantage of the shape information available at the decoder side. A well-known representative of this class is the SA-DCT. However, having been primarily designed for intraframe coding, it is shown that the transform is suboptimal when applied to interframe coding. Using a suitable covariance model, it is demonstrated that a rescaled, orthonormalized transform much closer approximates the optimal shape-adaptive eigentransform of motion-compensated frame difference images. Rate distortion curves verify that orthonormalization improves coding efficiency in interframe coding by up to 2 dB while not adding to complexity. In a comparison, it is finally shown that extrapolation and SA-DCT perform very closely in the case of low data rates, while there is a clear advantage for the shape-adaptive transform in the case of high-quality video coding.
A tanh substitution technique for the analysis of abrupt and graded interface multilayer dielectric stacks (1991)

The authors report a new analytical technique for estimating the peak reflectivity of lossless dielectric stacks with combinations of quarter and/or half-wave thicknesses. A simple variable substitution is used to transform the standard formula for the reflectivity of a Fabry-Perot resonator into a remarkably simplified form. The resulting expressions for reflectivity are intuitively appealing, allowing use of additive algebra to calculate the peak reflectivity of a multilayer dielectric stack.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Síndrome de Waardenburg: las discapacidades y el aspecto físico, su vinculación con el rendimiento académico y las relaciones sociales (2012)

Introduction: Waardenburg's syndrome is a rare entity, having a certain degree of disability when sensorineural hypoacusis and visual disability appear. A family of 26 carriers (all them alive) of Waardenburg's syndrome who lives in Sandino municipality, Pinar del Rio province was detected. Objective: to determine the possible association of disabilities with academic achievement and social relations among these subjects. Material and method: an observational, cross-sectional and descriptive case-study was carried out with people belonging to a family suffering from Waardenburg's syndrome in Sandino municipality. Results: this research incorporates important aspects of Waardenburg's syndrome not previously described; which offer the possibility of showing them in a new way to improve and update knowledge of this entity. Conclusions: hearing disabilities together with physical features were the main difficulties to find a job and to perform it efficiently in people suffering from Waardenburg's syndrome.
A DNA-binding protein factor recognizes two binding domains within the octopine synthase enhancer element. (1990)

A protein that binds to the enhancing element of the octopine synthase gene has been identified in nuclear extracts from maize cell suspension cultures. Two protein-DNA complexes are distinguishable by electrophoretic mobility in gel retardation assays. Footprint analyses of these low and high molecular weight complexes show, respectively, half and complete protection of the ocs-element DNA from cleavage by methidiumpropyl-EDTA.FE(II). Two lines of evidence indicate that the element has two recognition sites, each of which can bind identical protein units. Elements that are mutated in one or the other half and form only the low molecular weight complex interfere with the formation of both the low and high molecular weight complexes by the wild-type element. Protein isolated from a complex with only one binding site occupied can bind to the wild-type ocs-element and generate complexes with protein occupying one or both binding sites. Occupation of both sites of the ocs-element is a prerequisite for transcriptional enhancement.
CoQ<sub>10</sub>: Could it have a role in cancer management? (1999)

Coenzyme Q10 or ubiquinone has been shown to have both anti-cancer and immune system enhancing properties when tested in animals. Preliminary results reported here suggest that it might inhibit tumour-associated cytokines. Clinical studies conducted with combination therapies of CoQ10 and other antioxidants are ongoing, but the results are difficult evaluate owing to the lack of proper control groups and of initial randomisation. Also on the basis of some anti-cancer effects of antioxidants reported in literature, further animal studies and a proper clinical trial of coenzyme Q10 in cancer patients are needed.
Quantitative description of analyte migration behavior based on dynamic complexation in capillary electrophoresis with one or more additives (1997)

A comprehensive theory is proposed to describe the migration behavior of analytes in capillary electrophoresis (CE) when one or more additives are present in the buffer solution. This theory amalgamates and extends the previous work done by others. The capacity factor (k') in this theory is defined as the product of the equilibrium constant and the additive concentration, thus, k' changes linearly with additive concentration. The net electrophoretic mobility of an analyte is a function of k', therefore, it can be changed by varying the additive concentration. Three parameters are needed to predict the mobility of an analyte in a one-additive CE system: the mobility of the free analyte, the mobility of the complex, and the equilibrium constant for the analyte-additive interaction (which determines the fraction of the free analyte at different additive concentrations). When additives are used, the change in viscosity obscures this relationship, therefore, a viscosity correction factor is required to convert all mobilities to an ideal state where the viscosity remains constant. The migration behavior of an analyte in a solution with multiple additives can be predicted and controlled, once the equilibrium constants of the interactions between the analyte and each of the additives are obtained separately. beta-Cyclodextrin and hydroxypropyl-beta-cyclodextrin are used as additives and the migration behavior of phenol, p-nitrophenol, and benzoic acid are studied as a model system to verify this theory. When the necessary viscosity correction factor is included, the net electrophoretic mobilities of the analytes obtained from experimental results agree with the values predicted by the theory based on dynamic complexation. Although only experiments with one and two additives were carried out to verify the theory, the equations apply to situations when more than two additives are used. The relationship between the theories of electrophoresis and chromatography is clarified.