gebhart/patrepeval huggingface dataset:
Monitoring-based auto-scalability across hybrid clouds (2018)

Cloud computing is a relatively new type of Internet-based computing that becomes more and more popular. Using methods like virtualization, adopting architectures based on microservices, automation of building and deployment processes, Cloud could provide on-demand resources and scale them accordingly to a Service Level Agreement (SLA). Even if there are a lot of Cloud computing providers (like Amazon AWS, Microsoft Azure, IBM, Google etc.), many of them providing advanced services, already deployed technologies, auto-scaling and monitoring tools, on the long run a private Cloud could cost less than a public Cloud. On the other hand, a private Cloud has the disadvantage of lacking hardware resources for scaling an unexpected spike of usage or periodical growths in the number of requests. This problem could be solved using a public Cloud provider API for extending the hardware by buying and selling resources, using a pay-per-use or a pay-as-you-go model. This paper describes and evaluates a private Cloud architecture capable of on demand deployment of microservices based applications, monitoring every instance using CPU, memory, networking and disk data collectors' software, monitoring every task queue and horizontally auto-scaling the number of instances per service. Using Cloud monitoring data, SLA and budget constraints we decide if a new instance should be spawned or terminated in the private Cloud or in a public Cloud. From the customer point of view the process of auto-scaling across the hybrid Cloud is transparent, but requires a horizontally scalable service. We will illustrate our work running an application packaged as microservices in containers in a Kubernetes private Cloud that will be extended using public resources from AWS. The results of the paper offers an architectural model that can be used to build an in-house, scalable Cloud.
Dynamic line rating in the operating environment (1990)

The authors present power line data and dynamic line rating statistics obtained during a one-year study in new York State. Conclusions from the study apply specifically to the Porter/Rotterdam line Hash 30. Dynamic line ratings, defined as the minimum dynamic rating for the power line, were 20% lower than the average or single-station ratings. The greatest gains to dynamic line rating come from the limited time or transient rating. Limited time dynamic ratings derive their added benefit from the use of actual preload conductor temperatures in the rating calculation rather than the 95 degrees C conductor temperature assumed by many utilities. A forecast rating algorithm is proposed for calculating power line ratings intended to remain valid over a defined period of time in the future with minimal risk. Based on the algorithm, the 4-h forecast ratings were found to be 12% lower on the average than dynamic line ratings.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Imaging in Parkinson’s disease (2016)

The clinical presentation of Parkinson's disease (PD) is heterogeneous and overlaps with other conditions, including the parkinsonian variant of multiple system atrophy (MSA-P), progressive supranuclear palsy (PSP) and essential tremor. Imaging of the brain in patients with parkinsonism has the ability to increase the accuracy of differential diagnosis. Magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT) and positron emission tomography (PET) allow brain imaging of structural, functional and molecular changes in vivo in patients with PD. Structural MRI is useful to differentiate PD from secondary and atypical forms of parkinsonism. 123I-ioflupane (DaTSCAN(TM)) SPECT is a valid tool in the differential diagnosis between PD and non-degenerative tremors, while cardiac 123I-metaiodobenzylguanidine SPECT and 18F-fluorodeoxyglucose PET are valid in the differential diagnosis between PD and atypical parkinsonism (MSA-P, PSP). However, despite significant evidence for the utility of neuroimaging in assessing parkinsonian patients, none of the neuroimaging techniques are specifically recommended for routine use in clinical practice. Hopefully, future larger trials will help to demonstrate additional evidence for the clinical utility of neuroimaging and will include an analysis of the financial benefits for the NHS in the longer term management of the patients.
Effects of sarin on the nervous system in rescue team staff members and police officers 3 years after the Tokyo subway sarin attack. (2001)

Although the clinical manifestations of acute sarin poisoning have been reported in detail, no comprehensive study of the chronic physical and psychiatric effects of acute sarin poisoning has been carried out. To clarify the chronic effects of sarin on the nervous system, a cross-sectional epidemiologic study was conducted 3 years after the Tokyo subway sarin attack. Subjects consisted of the rescue team staff members and police officers who had worked at the disaster site. Subjects consisted of 56 male exposed subjects and 52 referent subjects matched for age and occupation. A neurobehavioral test, stabilometry, and measurement of vibration perception thresholds were performed, as well as psychometric tests to assess traumatic stress symptoms. The exposed group performed less well in the backward digit span test than the referent group in a dose-effect manner. This result was the same after controlling for possible confounding factors and was independent of traumatic stress symptoms. In other tests of memory function, except for the Benton visual retention test (mean correct answers), effects related to exposure were also suggested, although they were not statistically significant. In contrast, the dose-effect relationships observed in the neurobehavioral tests (psychomotor function) were unclear. None of the stabilometry and vibration perception threshold parameters had any relation to exposure. Our findings suggest the chronic decline of memory function 2 years and 10 months to 3 years and 9 months after exposure to sarin in the Tokyo subway attack, and further study is needed.
Optimised voltage control for distributed generation (2015)

The supply of electrical energy is increasingly being sourced from distributed generators. Voltage management is a key feature of any power system and traditionally regulation on the distribution system is maintained to static set points. This paper highlights the inefficiencies of continuing to regulate voltage in this manner for a system with distributed generation. The generation hosting capacity is dependent on a number of factors, namely; thermal limitations, steady state voltage limitations, voltage fluctuations and voltage quality. All are threatened by the unnecessary flow of reactive power sourced from distributed units brought on by mismanaged secondary voltage control. This work presents a decentralised approach to regulating voltage and power flows on a distribution system that hosts both generation and demand using controllers local to transformers and distributed generators.
Photoconductivity Speed of Response for High Intensity Excitation in Cadmium Sulfide and Selenide (1956)

The rise and decay time of photoconductivity in single crystals, sintered layers, and evaporated layers of cadmium sulfide and cadmium selenide with a wide range of sensitivities, has been measured for excitation at room temperature by a 1900°K incandescent source giving 1740 ft-c illumination on the sample. The data thus obtained are useful for determining the dependence of the speed of response on the sample's photosensitivity and for estimating a practical upper limit to the speed of response of these photoconductors. The minimum response times found for the samples tested were rise time of 250 μsec and decay time of 300 μsec for cadmium sulfide and rise time of 17 μsec and decay time of 8 μsec for cadmium selenide.
MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4α, Modulating the Expression of Metabolic Enzymes and Cell Cycle (2009)

Hepatocyte nuclear factor (HNF) 4alpha is a key transcription factor regulating endo/xenobiotic-metabolizing enzymes and transporters. We investigated whether microRNAs are involved in the regulation of human HNF4alpha. Potential recognition elements for miR-24 (MRE24) were identified in the coding region and the 3'-untranslated region (3'-UTR), and those for miR-34a (MRE34a) were identified in the 3'-UTR in HNF4alpha mRNA. The HNF4alpha protein level in HepG2 cells was markedly decreased by the overexpression of miR-24 and miR-34a. The HNF4alpha mRNA level was significantly decreased by the overexpression of miR-24 but not by miR-34a. In luciferase analyses in HEK293 cells, the reporter activity of plasmid containing the 3'-UTR of HNF4alpha was significantly decreased by miR-34a. The reporter activity of plasmid containing the HNF4alpha coding region downstream of the luciferase gene was significantly decreased by miR-24. These results suggest that the MRE24 in the coding region and MRE34a in the 3'-UTR are functional in the negative regulation by mRNA degradation and translational repression, respectively. The down-regulation of HNF4alpha by these microRNAs resulted in the decrease of various target genes such as cytochrome P450 7A1 and 8B1 as well as morphological changes and the decrease of the S phase population in HepG2 cells. We also clarified that the expressions of miR-24 and miR-34a were regulated by protein kinase C/mitogen-activated protein kinase and reactive oxygen species pathways, respectively. In conclusion, we found that human HNF4alpha was down-regulated by miR-24 and miR-34a, the expression of which are regulated by cellular stress, affecting the metabolism and cellular biology.
CBSD: The Celestial Background Scene Descriptor (1993)

This report documents the Celestial Background Scene Descriptor (CBSD) program which is a suite of models to simulate the radiance of astronomical sources. The model simulate the contribution of the celestial background in the wavelength regime 2 to 30 micrometers with a positional accuracy of 2 arcseconds. The output of the models are tables and images suitable for use in sensor simulation. The CBAMP model calculates the thermal radiance and scattered light for the solar system objects including the Sun, Moon, the planets, the Galilean Satellites, 4559 numbered asteroids, and 9643 unnumbered asteroids. The solar system dust cloud (Zodiacal light model CBZODY uses a Lorentzian out of the plane dust density distribution to derive a number density from which the emitted and scattered radiances are computed. The stellar point sources model, CBPNTS, is a 'fast' running scene generator version of the Air Force/NASA/Ames statistical point source model, SKY. The sky is divided into 899 regions with size inversely proportional to stellar density. In addition, there are 87 different spectral classes, including 82 classes, including 82 classes of stars, two classes each of planetary and reflection nebulae, and one of compact HII regions. The nature of the galactic infrared cirrus is discussed
A problem in the analysis of geophysical data (1957)

Abstract The problem is to analyze mapped data into components which may be termed "trend" and "residual." The approach used is polynomial fitting by least squares, following the method of DeLury when the data are evenly distributed (or sampled), and of Kendall when they are not. The DeLury method, however, is extended somewhat in scope to include missing values. A number of statistical tests are discussed which should assist in determining the optimum amount of complexity to ascribe to "trend." The attitude taken throughout this paper is unbiased in the sense that positive and negative residuals are held a priori to be equally likely. An example is given of the regional correction of a gravity survey designed to explore for sulfides near Val d'Or, Quebec. In conclusion, a brief discussion is given of the advantages of polynomial fitting over smoothing and "gridding" methods from the point of view of labor and costs.
Serum Markers of Angiogenesis and Myocardial Ultrasonic Tissue Characterization in Patients with Dilated Cardiomyopathy (2005)

The increase in serum VEGF and IL-13 may be closely related to alterations in myocardial texture in DCM.
Gamma-S crystallin gene (CRYGS) mutation causes dominant progressive cortical cataract in humans (2005)

Background: Congenital or childhood cataract is clinically and genetically a highly heterogeneous lens disorder in children. Autosomal dominant inheritance is most common. Objective: To report the identification of a mutation in the human CRYGS gene. Subjects and methods: A large six generation family affected by progressive polymorphic cortical cataract was investigated. After excluding loci for known cataract candidate genes using 39 fluorescent microsatellite markers, a whole genome scan was carried out. Results: The disease was associated with inheritance of a 20.7 cM locus on chromosome 3q26.3-qter, with a maximum LOD score of 6.34 (θ = 0) at marker D3S1602. Haplotype analysis indicated that the disease gene lay at approximately 2.8 Mb physical intervals between D3S1571 and D3S3570 and contained CRYGS on 3q27.3. By sequencing the CRYGS gene, a distinct 1619G→T (AC068631) heterozygous missense mutation in exon 2 was identified, co-segregating with the disease phenotype in this family and resulting in a glycine (GGC) to valine residue (GTC) substitution in codon 18 (NP_060011). Conclusions: This report is the first description of a mutation in CRYGS with autosomal dominant cataract in humans.
Piezoelectric doping in AlInGaN/GaN heterostructures (1999)

We report on the piezoelectric doping and two-dimensional (2D) electron mobility in AlInGaN/GaN heterostructures grown on 6H–SiC substrates. The contribution of piezoelectric doping to the sheet electron density was determined using an In-controlled built-in strain-modulation technique. Our results demonstrate that in strained AlGaN/GaN heterostructures, the piezoelectric field generates at least 50% of the 2D electrons. The strain modulation changes the potential distribution at the heterointerface, which, in turn, strongly affects the 2D electron mobility, especially at cryogenic temperatures. The obtained results demonstrate the potential of strain engineering and piezoelectric doping for GaN-based electronics.
Solid-phase radiosynthesis of [11C]WAY 100635 (1996)

An efficient, fast and simple method is described for the radiosynthesis of the potent and selective 5-HT1A antagonist [O-methyl-11C]-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexane carboxamide ([11C]WAY 100635). [11C]Iodomethane was effectively trapped on a C18 reverse-phase cartridge at ambient temperature where it reacted rapidly with the normethyl precursor, N-[2-[4-(2-hydroxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexane carboxamide. Following high performance liquid chromatography purification and formulation, [11C]WAY 100635 was obtained in high radiochemical yields (40%, uncorrected from [11C]Iiodomethane) in a synthesis time of 25 min with an average specific activity of (at end-of-synthesis) 33 GBq/μmole (900 mCi/μmole).
Effects of floating planes in three-dimensional packaging structures on simultaneous switching noise (2002)

The effects of floating conductors in three-dimensional packaging structures are investigated. The simulations are based on a frequency-dependent integral equation formulation for the calculation of the magnetoquasistatic current distribution in complex interconnect structures. The calculated current distributions are used to develop an inductance/resistance equivalent circuit representation of the package that can be used as a subcircuit in SPICE for simultaneous switching noise calculations. The model is frequency dependent and captures the effect that multiple solid/meshed ground/power planes, pins, vias and traces have on overall package inductive performance. The impact of floating planes, such as a heat spreader under a BGA structure, on the mutual inductances of the structure is demonstrated. The frequency dependence of the floating plane effects is examined also. The behavior of the induced eddy currents in the floating plane is investigated also, particularly in the vicinity of interconnect discontinuities. Switching noise results obtained using SPICE simulation and the generated inductance/resistance equivalent package models show the effects of floating planes on switching noise.
Addition of Angiotensin II Type 1 Receptor Blocker to CCR2 Antagonist Markedly Attenuates Crescentic Glomerulonephritis (2011)

The monocyte chemoattractant protein-1 (MCP-1)/CC-chemokine receptor 2 (CCR2) pathway plays a critical role in the development of antiglomerular basement membrane (anti-GBM) nephritis. We recently showed angiotensin II (Ang II) infusion in rats activated MCP-1 and transforming growth factor-β1 (TGF-β1), which in turn induced macrophage infiltration of renal tissues. This study was performed to demonstrate that combination therapy with a CCR2 antagonist (CA) and an Ang II type 1 receptor blocker (ARB) ameliorated renal injury in the anti-GBM nephritis model. An anti-GBM nephritis rat model developed progressive proteinuria and glomerular crescent formation, accompanied by increased macrophage infiltration and glomerular expression of MCP-1, angiotensinogen, Ang II, and TGF-β1. Treatment with CA alone or ARB alone moderately ameliorated kidney injury; however, the combination treatment with CA and ARB dramatically prevented proteinuria and markedly reduced glomerular crescent formation. The combination treatment also suppressed the induction of macrophage infiltration, MCP-1, angiotensinogen, Ang II, and TGF-β1 and reversed the fibrotic change in the glomeruli. Next, primary cultured glomerular mesangial cells (MCs) stimulated by Ang II showed significant increases in MCP-1 and TGF-β1 expression. Furthermore, cocultured model consisting of MCs, parietal epithelial cells, and macrophages showed an increase in Ang II-induced cell proliferation and collagen secretion. ARB treatment attenuated these augmentations. These data suggest that Ang II enhances glomerular crescent formation of anti-GBM nephritis. Moreover, our results demonstrate that inhibition of the MCP-1/CCR2 pathway with a combination of ARB effectively reduces renal injury in anti-GBM nephritis.
A CRITICAL REVIEW OF NONCONVENTIONAL APPROACHES TO LIGHTNING PROTECTION (2002)

The conventional technique for the lightning protection of structures is described in the U.S. National Standard, NFPA 780, and in many other national and international lightning protection standards. Two nonconventional techniques, known generically as “lightning elimination” and “early streamer emission,” are claimed by their proponents to be superior to the conventional lightning protection technique. We review the literature on these nonconventional approaches as well as the pertinent lightning literature and conclude that the suggested superiority of the nonconventional techniques over the conventional method is not supported by the available experimental data or by theory.
Two Mechanisms for Supercontraction in <i>Nephila</i> Spider Dragline Silk (2011)

Supercontraction in dragline silk of Nephila edulis spider is shown to have two distinct components revealed by single fiber measurements using dynamic mechanical thermal analysis. The first component relies on a contraction of maximum 13% and seems to be associated with relaxation processed through the glass transition, T(g), as is induced by increasing temperature and/or humidity. The second component is induced by liquid water to the total contraction of 30%. The T(g)-induced contraction is linearly correlated with the restraining stress on the fiber, and the mechanical properties of the partially contracted silk have mechanical profiles that differ from both native and fully supercontracted fibers. Here we present novel supercontraction data and discuss their structural origins, examining the relaxation of stretched orientation in the different primary structure sequences.
Characterization of capacitive 3D deep trench mask open structures using scatterometry (2007)

A non-destructive and fast optical solution for characterization of 3D deep trench mask open structures containing two holes per unit cell is presented. It is discussed that measurement sensitivity depends on wafer orientation. A weighted reference measurement system using data from scatterometry combined with CD-SEM and CD-AFM techniques after HF removal of the top BSG layer demonstrates adequate performance of scatterometry for high aspect ratio 3D process control implementations. For example the BCD major and minor axis scatterometry total measurement uncertainty values are about a factor 2 better than the corresponding results obtained using CD-SEM and CD-AFM. While scatterometry data exhibit close to unity slope for both TCD and BCD, corresponding CD-SEM and CD-AFM performances show significantly stronger dependence on depth. Hence, Scatterometry sensitivity to CD variation is less depth sensitive which is a preferred high volume manufacturing property.
Equivariant functions and vector-valued modular forms (2013)

For any discrete group Γ and any two-dimensional complex representation ρ of Γ, we introduce the notion of ρ-equivariant functions, and we show that they are parametrized by vector-valued modular forms. We also provide examples arising from the monodromy of differential equations.
Poly(thieno[3,4-<i>b</i>]thiophene). A New Stable Low Band Gap Conducting Polymer (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTPoly(thieno[3,4-b]thiophene). A New Stable Low Band Gap Conducting PolymerKyunghoon Lee and Gregory A. SotzingView Author Information Department of Chemistry and the Polymer Program, Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269-3136 Cite this: Macromolecules 2001, 34, 17, 5746–5747Publication Date (Web):July 12, 2001Publication History Received10 April 2001Revised28 May 2001Published online12 July 2001Published inissue 1 August 2001https://pubs.acs.org/doi/10.1021/ma0106245https://doi.org/10.1021/ma0106245rapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views2683Altmetric-Citations93LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Electrical conductivity,Plastics,Polymerization,Polymers,Thiophenes Get e-Alerts