gebhart/patrepeval huggingface dataset:
Interaction of oxomolybdenum species with .gamma.c-alumina and .gamma.c-alumina modified by silicon. 2. The molybdena/.gamma.c-alumina and molybdena/silica/.gamma.c-alumina systems (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInteraction of oxomolybdenum species with .gamma.c-alumina and .gamma.c-alumina modified by silicon. 2. The molybdena/.gamma.c-alumina and molybdena/silica/.gamma.c-alumina systemsP. Sarrazin, S. Kasztelan, E. Payen, J. P. Bonnelle, and J. GrimblotCite this: J. Phys. Chem. 1993, 97, 22, 5954–5961Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/j100124a029https://doi.org/10.1021/j100124a029research-articleACS PublicationsRequest reuse permissionsArticle Views240Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Introduction (1989)

The topics in this book have been developed from fundamentals. The introductory section and the chapters on the basic principles of heat, light and sound will be of particular importance if little physics has been studied before. These parts of the book will also be useful to anyone needing revision.
One-Pot Synthesis, Encapsulation, and Solubilization of Size-Tuned Quantum Dots with Amphiphilic Multidentate Ligands (2008)

We report one-pot synthesis, encapsulation, and solubilization of high-quality quantum dots (QDs) based on the use of amphiphilic and multidentate polymer ligands. In this "all-in-one" procedure, the resulting QDs are first capped by the multidentate ligand and are then spontaneously encapsulated and solubilized by a second layer of the same multidentate polymer upon exposure to water. In addition to providing better control of nanocrystal nucleation and growth kinetics (including resistance to Ostwald ripening), this procedure allows for in situ growth of an inorganic passivating shell on the nanocrystal core, enabling one-pot synthesis of both type-I and type-II core-shell QDs with tunable light emission from visible to near-infrared wavelengths.
Creutzfeldt-Jakob Disease Transmitted by a Cadaveric Dura Mater Graft (1994)

We report a case of Creutzfeldt-Jakob disease developing in a 31-year-old woman 56 months after she received a cadaveric dura mater graft after the removal of a giant pituitary adenoma. Creutzfeldt-Jakob disease was confirmed by a brain autopsy and the existence of an abnormal isoform of prion protein, verified by both immunohistochemical and Western blot analysis. Moreover, prion protein gene analysis was shown in this case to possess a wild-type genotype. The characteristics of Creutzfeldt-Jakob disease after a cadaveric dura mater graft are reviewed and discussed.
Kruppel-like Factor KLF10 Targets Transforming Growth Factor-β1 to Regulate CD4+CD25− T Cells and T Regulatory Cells (2009)

CD4(+)CD25(+) regulatory T cells (T regs) play a major role in the maintenance of self-tolerance and immune suppression, although the mechanisms controlling T reg development and suppressor function remain incompletely understood. Herein, we provide evidence that Kruppel-like factor 10 (KLF10/TIEG1) constitutes an important regulator of T regulatory cell suppressor function and CD4(+)CD25(-) T cell activation through distinct mechanisms involving transforming growth factor (TGF)-beta1 and Foxp3. KLF10 overexpressing CD4(+)CD25(-) T cells induced both TGF-beta1 and Foxp3 expression, an effect associated with reduced T-Bet (Th1 marker) and Gata3 (Th2 marker) mRNA expression. Consistently, KLF10(-/-) CD4(+)CD25(-) T cells have enhanced differentiation along both Th1 and Th2 pathways and elaborate higher levels of Th1 and Th2 cytokines. Furthermore, KLF10(-/-) CD4(+)CD25(-) T cell effectors cannot be appropriately suppressed by wild-type T regs. Surprisingly, KLF10(-/-) T reg cells have reduced suppressor function, independent of Foxp3 expression, with decreased expression and elaboration of TGF-beta1, an effect completely rescued by exogenous treatment with TGF-beta1. Mechanistic studies demonstrate that in response to TGF-beta1, KLF10 can transactivate both TGF-beta1 and Foxp3 promoters, implicating KLF10 in a positive feedback loop that may promote cell-intrinsic control of T cell activation. Finally, KLF10(-/-) CD4(+)CD25(-) T cells promoted atherosclerosis by approximately 2-fold in ApoE(-/-)/scid/scid mice with increased leukocyte accumulation and peripheral pro-inflammatory cytokines. Thus, KLF10 is a critical regulator in the transcriptional network controlling TGF-beta1 in both CD4(+)CD25(-) T cells and T regs and plays an important role in regulating atherosclerotic lesion formation in mice.
An efflux transporter PbrA and a phosphatase PbrB cooperate in a lead‐resistance mechanism in bacteria (2009)

The gene cluster pbrTRABCD from Cupriavidus metallidurans CH34 is thought to encode a unique, specific resistance mechanism for lead. However, the exact functions of these genes are unknown. In this study we examine the metal specificity and functions of pbrABCD by expressing these genes in different combinations and comparing their ability to restore Pb(2+), Zn(2+) and Cd(2+) resistance in a metal-sensitive C. metallidurans strain DN440. We show that lead resistance in C. metallidurans is achieved through the cooperation of the Zn/Cd/Pb-translocating ATPase PbrA and the undecaprenyl pyrophosphate phosphatase PbrB. While PbrA non-specifically exported Pb(2+), Zn(2+) and Cd(2+), a specific increase in lead resistance was observed when PbrA and PbrB were coexpressed. As a model of action for PbrA and PbrB we propose a mechanism where Pb(2+) is exported from the cytoplasm by PbrA and then sequestered as a phosphate salt with the inorganic phosphate produced by PbrB. Similar operons containing genes for heavy metal translocating ATPases and phosphatases were found in several different bacterial species, suggesting that lead detoxification through active efflux and sequestration is a common lead-resistance mechanism.
Overexpression of stearoyl-CoA desaturase 1 in bone marrow mesenchymal stem cells enhance the expression of induced endothelial cells (2014)

This study suggested that overexpression of SCD1 in BM-MSCs could increase the expression of induced endothelial cells in vitro.
Growing Up With a Facial Hemangioma: Parent and Child Coping and Adaptation (1998)

Objective. To better understand the experiences, challenges, and adaptations of parents with children who have disfiguring facial hemangiomas. Design. Qualitative, descriptive. Methods. In-depth interviews were performed with the parent(s) of 25 children, aged 5 months to 8 years. Each child was referred to the Pediatric Dermatology Practice, Department of Dermatology, University of California, San Francisco, with a facial hemangioma of 1 cm diameter or greater. Interviews were ethnographic in style, centering on the description by parents of the particular challenges faced, supports received, and adaptive strategies developed in coping with their child's hemangioma. Analysis was by open coding of interview transcripts. Coded statements were organized within common categories and these further gathered into 4 principal themes: 1) parental emotion and adaptation; 2) experiences with public reactions; 3) issues related to parent-child interactions; and 4) expressed satisfaction/dissatisfaction with medical care. Results. Disfiguring facial hemangiomas were found to be associated with parental reactions of disbelief, fear, and mourning, particularly during the growth phase. Reactions of strangers forced parents to confront varied aspects of social stigmatization. A broad array of effects on the parent-child interaction were observed, often connected with variables extrinsic to the hemangioma, including especially the support and acceptance by the extended family. Half of those studied expressed substantial dissatisfaction with aspects of their medical care. Conclusions. Disfiguring facial hemangiomas in young children are frequently associated with parental reactions of loss and grief, despite the generally benign nature of the lesion and the prognosis for eventual involution. Physicians are faced with specific challenges in providing effective anticipatory guidance and support to parents.
Continuous Mixed Venous Oximetry in Critically I11 Surgical Patients. 'High-Tech' Cost-Effectiveness (1987)

Departments of Surgery, Hartford Hospital, Hartford, and University of Connecticut School of Medicine, Farmington, Connecticut
Detection of apoptosis in live cells by MitoTracker? Red CMXRos and SYTO dye flow cytometry (1997)

We characterized the ability of six SYTO nucleic acid stains and a mitochondrial stain to resolve by flow cytometry camptothecin-induced apoptotic and non-apoptotic cells. Staining live human lymphoid B-cells showed such resolution with SYTO 11, 12, 13, 14, and 16 dyes. H9, HL-60, and Jurkat cells did not show resolution with the SYTO 12 dye, but did with the others. SYTO 15 dye did not show resolution with any cell type. RNase A treatment of fixed lymphoid B-cells strongly reduced fluorescence after staining with SYTO 12 dye; the other SYTO dyes showed little or no RNase A sensitivity. Reduced SYTO 12 fluorescence may reflect RNA breakdown during apoptosis, while decreased fluorescence of the other SYTO dyes in apoptotic cells may be due to chromosomal alterations during apoptosis. In all cell types tested, clear resolution between apoptotic and non-apoptotic cells was observed with the MitoTracker Red dye CMXRos. In double-staining experiments, cells exhibiting reduced SYTO 11 fluorescence were the same as those showing decreased CMXRos fluorescence. We conclude that changes in nucleic acid stability or conformation may vary during apoptosis from one cell type to another, but mitochondrial demise may be common to all apoptotic pathways.
An electrofusion chip with a cell delivery system driven by surface tension (2008)

We have fabricated an electric cell fusion chip with an embedded cell delivery function driven by surface tension and evaluated its performance with several types of plant cells. The chip consists of a polydimethylsiloxane-based microchannel with a fusion chamber and gold–titanium (Au–Ti) electrodes. The velocity profiles of the microfluid in the channel and fusion chamber were calculated to predict cell movement, and the electric field distribution between the electrodes was also calculated in order to determine the appropriate electrode shape. The range of the fluid velocity in the fusion chamber is 20–50 µm s−1 and the measured speed of the cells is approximately 45 µm s−1, which is sufficiently slow for the motion of the cells in the fusion chamber to be monitored and controlled. We measured the variation of the pearl chain ratio with frequency for five kinds of plant cells, and determined that the optimal frequency for pearl chain formation is 1.5 MHz. The electrofusion of cells was successfully carried out under ac field (amplitude: 0.4–0.5 kV cm−1, frequency: 1.5 MHz) and dc pulse (amplitude: 1.0 kV cm−1, duration: 20 ms) conditions.
Approach to generating test data from set expressions (2008)

Software testing guaranteeing and improving the software quality becomes the main concerned point in the field.Test data generation effects software testing directly.The preconditions based on relation operators in formal specifications is used to generate test data.A test criterion for generating test data from set relation operators is proposed,and then an algorithm is developed that generates test data satisfying the test criterion.The test data generated by the algorithm can effectively detect errors in codes corresponding to the set relation expression.An example is given to illustrate the effect of detecting errors in codes.
Insight into the Binding Mode for Cyclopentapeptide Antagonists of the CXCR4 Receptor (2006)

The finding that the chemokine receptor CXCR4 is involved in T-cell HIV entry has encouraged the development of antiretroviral drugs targeting this receptor. Additional evidence that CXCR4 plays a crucial role in both angiogenesis and metastasis provides further motivation for the development of a CXCR4 inhibitor for therapeutic applications in oncology. To facilitate the design of such ligands, we have investigated the possible binding modes for cyclopentapeptide CXCR4 antagonists by docking 11 high/medium affinity cyclopentapeptides to a developed three-dimensional model of the CXCR4 G-protein-coupled receptor's transmembrane region. These ligands, expected to bind in the same mode to the receptor, were docked in the previously deduced receptor-bound conformation [Våbenøet al., in press; doi 10.1002/bip.20508]. Ligand-receptor complexes were generated using an automated docking procedure that allowed ligand flexibility. By comparing the resulting ligand poses, only two binding modes common for all 11 compounds were identified. Inspection of these two ligand-receptor complexes identified several CXCR4 contact residues shown by mutation to be interaction sites for ligands and important for HIV gp120 binding. Thus, the results provide further insight into the mechanism by which these cyclopentapeptides block HIV entry as well as a basis for rational design of CXCR4 mutants to map potential contacts with small peptide ligands.
Pròleg: El desig teatral d'Europa : l'escenari de les paradoxes (2013)

La coŀecció "Escenes Europees", coordinada per Francesc Foguet i Núria Santamaria, és una iniciativa del Grup de Recerca en Arts Escèniques de la Universitat Autònoma de Barcelona.
Defects in Aqueous Film-Coated Tablets (2008)

Film coating is a process that involves the deposition of a membrane-consisting of polymer, plasticizer, colorant, and possibly other additives-onto the surface of a pharmaceutical dosage form, typically a tablet or a granule. Compared to the conventional sugar coat, the film coat is relatively thin, i.e., typically 10 to 100 μm. Although the technology involved in the application of such a thin coating to a substance is not new, having precedents in both the paints and adhesive technologies, problems do occur, resulting in a number of film defects. These can either affect the visual appearance of the coated tablet or, more importantly, result in the loss of continuity of the film and thus affect the release of the active ingredient from the preparation. Over the past two decades, with the increasing use of aqueous film coating, the number of defects reported has increased dramatically.
The antiandrogens. When and how they should be used. (1993)

This article is a useful guide for treating androgen-related skin disorders such as androgenetic alopecia, acne, and hirsutism. All available antiandrogens are discussed, as well as treatment doses, efficacy, and mode of action.
Evaluated Enthalpies of Formation of the Stable Closed Shell C1 and C2 Chlorinated Hydrocarbons (2002)

Experimental data on the enthalpies of formation of chloromethanes, chloroethynes, chloroethenes, and chloroethanes are critically reviewed. Enthalpy of formation values for the C1 and C2 chlorinated hydrocarbons are highly cross-linked by various measured reaction equilibria and currently available sets of values are not internally self-consistent. It is shown that the early static bomb combustion calorimetry studies on highly chlorinated compounds generally give enthalpies of formation that are systematically more positive than later values derivable from rotating bomb combustion or equilibria studies. Those previously recommended values which were based mainly on the early static bomb work therefore need substantial revision. On the basis of more recent literature data obtained with rotating bomb combustion calorimetry, together with analyses of literature data on other reaction enthalpies and equilibria involving chlorinated hydrocarbons, an updated self-consistent set of ΔfHo[298.15 K] values for closed shell chlorinated C1 and C2 hydrocarbons (25 compounds) is recommended. Data on the enthalpies of vaporization are also reviewed and values of ΔvapH[298.15 K] and ΔvapHo[298.15 K] are recommended. The presently suggested enthalpies of formation for highly chlorinated alkenes and alkanes (particularly C2Cl4, C2HCl3, C2HCl5, and C2Cl6) are significantly (8–15 kJ mol−1) more negative than given by most previous evaluators. Values for the chloroethynes are 10–25 kJ mol−1 more positive than given in previous reviews and more limited changes are suggested for other compounds in the series.
Abnormal Transverse-Field Effects in Nonideal Type II Superconductors I. A Linear Array of Monofilamentary Wires (1982)

When an AC magnetic field was applied in the axial direction to a linear array of superconducting monofilamentary wires in the presence of a DC magnetic field perpendicular to the axes of the wires, it was found that the component of flux along the DC field changed its semi-quasistatic distribution in each cycle of the AC field and finally reached a uniform distribution after several tens of cycles. In the steady state, the AC component of flux showed a distribution of the Bean-London type with a reduced pinning force. For a small amplitude of AC field, the observed hysteresis loss increased with increase in the DC field. All of these characteristics exhibit a striking contrast to those of the so-called longitudinal-field effects, and may be called abnormal transverse-field effects; they have not been observed until now.
Cell polarity triggered by cell-cell adhesion via E-cadherin (2009)

Cell polarity is orchestrated by numerous extracellular cues, and guides events such as chemotaxis, mitosis and wound healing. In scrape-wound assays of cell monolayers, wound-edge cells orient their centrosomes towards the wound, a process that appears to depend on the formation of new cell-extracellular-matrix adhesions as cells spread into the wound. In direct contrast to scrape-wounded cells, isolated cells without cell-cell contacts failed to polarize, suggesting that asymmetry of cell-cell adhesions resulting from monolayer disruption might contribute to polarization. By using micropatterned substrates to engineer such asymmetries in kidney epithelial cells, we found that cell-cell contact induced displacement of the nucleus towards the contact, and also caused centrosomal reorientation and lamellipodial ruffling to the distal side of the nucleus. Upon release from micropatterned constraints, cells exhibited directed migration away from the cell-cell contact. Disrupting E-cadherin engagement randomized nuclear position and lamellipodial ruffling in patterned cultures, and abrogated scrape-wound-induced cell reorientation, but not migration rate. Polarity that was induced by cell-cell contact required an intact actin cytoskeleton and Cdc42 activity, but not RhoA or Rac signaling. Together, these findings demonstrate a novel role for cell-cell adhesion in polarization, and have implications for wound healing and developmental patterning.
Genetic polymorphism of drug-metabolizing enzymes and susceptibility to oral cancer (1999)

An individual difference in the susceptibility to chemical carcinogens is one of the most important factors in the estimate of risk of human cancer. Recently, it has been reported that genetic risk for tobacco-related cancers is associated with polymorphisms of the CYP1A1 and GSTM1 genes in terms of genotype frequencies and cigarette smoking dose. In this study, we investigated the inter-individual difference in genetically determined susceptibility to oral squamous cell carcinoma (SCC) in relation to cigarette smoking dose in a Japanese population. DNA samples were obtained from both patients and controls. We identified individuals at high risk genetically for oral SCC in terms of polymorphisms of the CYP1A1 and GSTM1 genes. This study then compared the estimated total number of cigarettes smoked by patients with those smoked by controls. In this case-control study, we estimated the odds ratios of susceptible to non-susceptible individuals. CYP1A1 genotype C and GSTM1 deficiency were frequently found among oral SCC patients. Patients with genotype C and GSTM1 deficiency contracted carcinoma after fewer cigarettes than those with other genotypes. Individuals with these two genotypes were at remarkably high risk at a low dose level of cigarette smoking. Individual differences in polymorphisms of the CYP1A1 and GSTM1 genes is one important factor in the estimate of risk of oral SCC at a low dose level of cigarette smoking.
Memory management for high-performance applications (2002)

I'd like to thank my advisor, Kathryn McKinley, and my de facto co-advisor Ben Zorn, for their invaluable guidance, insights, and help along
Non-volatile memory technologies for beyond 2010 (2005)

The development of Flash memory technology over the past decade has been one of the driving forces behind the tremendous growth in digital consumer applications, such as digital cameras, handheld music players and mobile phones. NAND Flash has been leading the way from 16Mb in 1994 to 4Gb today. This paper discusses the impact of continuous advances in NAND Flash technology on consumer applications and also reviews technical challenges to the further scaling of NAND and NOR Flash memories, while considering the possibility of other nonvolatile memory technologies for high density nonvolatile data storage beyond 2010.
Preparation of Some Mixed Dialkyl Phosphites (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of Some Mixed Dialkyl PhosphitesGennady M. KosolapoffCite this: J. Am. Chem. Soc. 1951, 73, 10, 4989Publication Date (Print):October 1, 1951Publication History Published online1 May 2002Published inissue 1 October 1951https://pubs.acs.org/doi/10.1021/ja01154a528https://doi.org/10.1021/ja01154a528research-articleACS PublicationsRequest reuse permissionsArticle Views167Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Oxone®: A Convenient Reagent for the Oxidation of Acetals (1999)

Symmetrical cyclic and acyclic acetals by oxidation with Oxone® gave the corresponding esters in good yield. Treatment of tetrahydropyranyl derivatives of alcohols with the same reagent resulted in oxidative regeneration of the alcohols.