gebhart/patrepeval huggingface dataset:
Control of Microbiological Hazards in the Laboratory (1969)

Abstract Occupationally acquired infections are a significant hazard among laboratory workers. Frequency rates found range from 0.1 to 50.0 infections per million man-hours. Unsafe acts or conditions are difficult to identify in approximately 80% of the cases. The sources and causes of such infections are discussed and criteria given for assessment of risk. Five specific approaches to controlling microbiological hazards are: (1) management support and administrative techniques, (2) vaccination of personnel, (3) use of correct laboratory techniques, (4) use of safety equipment, and (5) proper design of laboratories.
Review of Wireless Power Transfer Techniques (2018)

Wireless transfer refers to any of a number of methods by which electrical power is transferred from a source device or circuit to a sink device or circuit, using electromagnetic waves. Numerous techniques abound in the domain of wireless power transfer technology. The current paper carries out a brief review of the most salient concepts, with a special focus on far-field techniques.
Neuropsychological Changes after Cardiopulmonary Bypass for Coronary Artery Bypass Grafting (1998)

Biochemical markers demonstrate significant postoperative cerebral injury during and immediately after CPB. However, CPB for CABG does not lead to marked impairment of neuropsychological scores, and clinically relevant neurological findings were observed in one patient only.
Chitosan-coated Stainless Steel Screws for Fixation in Contaminated Fractures (2008)

Stainless steel screws and other internal fixation devices are used routinely to stabilize bacteria-contaminated bone fractures from multiple injury mechanisms. In this preliminary study, we hypothesize that a chitosan coating either unloaded or loaded with an antibiotic, gentamicin, could lessen or prevent these devices from becoming an initial nidus for infection. The questions investigated for this hypothesis were: (1) how much of the sterilized coating remains on the screw with simulated functional use; (2) is the unloaded or loaded chitosan coating bacteriostatic and biocompatible; and (3) what amount and rate does an antibiotic elute from the coating? In this study, the gentamicin eluted from the coating at a detectable level during 72 to 96 hours. The coating was retained at the 90% level in simulated bone screw fixation and the unloaded and loaded chitosan coatings had encouraging in vitro biocompatibility with fibroblasts and stem cells and were bacteriostatic against at least one strain of Staphylococcus aureus. The use of an antibiotic-loaded chitosan coating on stainless steel bone screws and internal fixation devices in contaminated bone fracture fixation may be considered after optimization of antibiotic loading and elution and more expanded in vitro and in vivo investigations with other organisms and antibiotics.
Activation of Vγ9Vδ2 T Cells by NKG2D (2005)

Human Vgamma9 Vdelta2 T cells recognize phosphorylated nonpeptide Ags (so called phosphoantigens), certain tumor cells, and cells treated with aminobisphosphonates. NKG2D, an activating receptor for NK cells, has been described as a potent costimulatory receptor in the Ag-specific activation of gammadelta and CD8 T cells. This study provides evidence that Vgamma9 Vdelta2 T cells may also be directly activated by NKG2D. Culture of PBMC with immobilized NKG2D-specific mAb or NKG2D ligand MHC class I related protein A (MICA) induces the up-regulation of CD69 and CD25 in NK and Vgamma9 Vdelta2 but not in CD8 T cells. Furthermore, NKG2D triggers the production of TNF-alpha but not of IFN-gamma, as well as the release of cytolytic granules by Vgamma9 Vdelta2 T cells. Purified Vgamma9 Vdelta2 T cells kill MICA-transfected RMA mouse cells but not control cells. Finally, DAP10, which mediates NKG2D signaling in human NK cells, was detected in resting and activated Vgamma9 Vdelta2 T cells. These remarkable similarities in NKG2D function in NK and Vgamma9 Vdelta2 T cells may open new perspectives for Vgamma9 Vdelta2 T cell-based immunotherapy, e.g., by Ag-independent killing of NKG2D ligand-expressing tumors.
High-power Q-switched erbium fiber laser using an all-fiber intensity modulator (1993)

We report on the demonstration of a Q-switched erbium-doped fiber laser using a novel all-fiber intensity modulator acting as an efficient intracavity switching element. Switching speed and holdoff losses are compatible with the Q-switching dynamics of rare-earth-doped fiber lasers. The modulator is completely integrated in a spliceless erbium- doped fiber cavity. Pulses of less than 15 ns full width at half maximum (FWHM) and peak power close to 400 W were obtained for a launched pumping power of 100 mW at 980 nm. This compact source could find many uses in applications such as nonlinear optics, laser ranging and remote sensing, eyesafe free-space communication, time-gated fiber sensor systems, and long-distance optical time-domain reflectometry.
Plastics from Natural Rubber (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPlastics from Natural RubberG. Salomon, G. J. van Amerongen, G. J. van Veersen, G. Schuur, and H. C. J. de DeckerCite this: Ind. Eng. Chem. 1951, 43, 2, 315–319Publication Date (Print):February 1, 1951Publication History Published online1 May 2002Published inissue 1 February 1951https://pubs.acs.org/doi/10.1021/ie50494a020https://doi.org/10.1021/ie50494a020research-articleACS PublicationsRequest reuse permissionsArticle Views145Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Hemolytic Activity of Fusobacterium necrophorum Culture Supernatants Due to Presence of Phospholipase A and Lysophospholipase (1979)

Culture supernatants of Fusobacterium necrophorum demonstrated hemolytic activity. The hemolysin(s), which was partially purified by ammonium sulfate precipitation, was temperature-dependent and heat labile. The spectrum of hemolytic activity against various erythrocytes included rabbit, human, and dog erythrocytes. Goats, sheep, and bovine erythrocytes showed only trace hemolysis. According to results of thin-layer chromatography, the hemolysin hydrolyzed rabbit erythrocyte phosphatidyl choline, phosphatidyl ethanolamine, lysophosphatidyl choline, and bovine phosphatidyl choline. Hydrolysis of egg yolk phosphatidyl choline, bovine phosphatidyl ethanolamine, cholesterol, 1,2-dipalmitin, 1,3-dipalmitin, sphingomyelin, or triolein was not detected by thin layer chromatography. A more sensitive procedure utilizing gas-liquid chromatography revealed that, of the substrates tested, the following were bein hydrolyzed: bovine and egg yolk phosphatidyl choline, lysophosphatidyl choline, alpha-palmito-beta-eleoyl-L-alpha lecithin and alpha-oleoyl-betal-palmitoyl-L-alpha lecithin. Substrates which were weakly hydrolyzed were bovine phosphatidyl ethanolamine, DL-alpha-hosphatidyl ethanolamine dipalmitoyl, 1,2-dipalmitin, 1,3-dipalmitin, and triolein.
Critical Review of Transcutaneous Vagus Nerve Stimulation: Challenges for Translation to Clinical Practice (2020)

Several studies have illustrated that transcutaneous vagus nerve stimulation (tVNS) can elicit therapeutic effects that are similar to those produced by its invasive counterpart, vagus nerve stimulation (VNS). VNS is an FDA-approved therapy for the treatment of both depression and epilepsy, but it is limited to the management of more severe, intervention-resistant cases as a second or third-line treatment option due to perioperative risks involved with device implantation. In contrast, tVNS is a non-invasive technique that involves the application of electrical currents through surface electrodes at select locations, most commonly targeting the auricular branch of the vagus nerve (ABVN) and the cervical branch of the vagus nerve in the neck. Although it has been shown that tVNS elicits hypo- and hyperactivation in various regions of the brain associated with anxiety and mood regulation, the mechanism of action and influence of stimulation parameters on clinical outcomes remains predominantly hypothetical. Suppositions are largely based on correlations between the neurobiology of the vagus nerve and its effects on neural activity. However, tVNS has also been investigated for several other disorders, including tinnitus, migraine and pain, by targeting the vagus nerve at sites in both the ear and the neck. As most of the described methods differ in the parameters and protocols applied, there is currently no firm evidence on the optimal location for tVNS or the stimulation parameters that provide the greatest therapeutic effects for a specific condition. This review presents the current status of tVNS with a focus on stimulation parameters, stimulation sites, and available devices. For tVNS to reach its full potential as a non-invasive and clinically relevant therapy, it is imperative that systematic studies be undertaken to reveal the mechanism of action and optimal stimulation modalities.
Fatty acid reductase in bioluminescent bacteria. Resolution from aldehyde reductases and characterization of the aldehyde product (1981)

Fatty acid reductase from the bioluminescent bacterium Photobacterium phosphoreum, has been partially purified free of aldehyde reductase activity and with a low endogenous fatty acid content permitting the characterization of the aldehyde product of the reaction. Two aldehyde reductases, both dependent on NADH, were separated by anion-exchange chromatography from the fatty acid reductase activity. The partially purified fatty acid reductase catalyzed the synthesis exclusively of long chain aldehydes from fatty acids in the presence of ATP and NADPH as demonstrated by the conversion of [3H]tetradecanoic acid to [3H]aldehyde. Comparison of the amount of [3H]aldehyde produced with the bioluminescence responses of luciferase to the aldehyde product and standard aldehydes, both with respect to maximum light intensity and luminescent decay, established that tetradecanoic acid has been converted to tetradecanal, the aldehyde of the same chain length. These results are consistent with a mechanism involving activation of the fatty acid with ATP followed by reduction of a fatty acyl intermediate to the corresponding aldehyde.
QT interval dispersion: a non-invasive marker of susceptibility to arrhythmia in patients with sustained ventricular arrhythmias? (1994)

QT interval dispersion may be a further non-invasive marker of susceptibility to ventricular arrhythmias.
Meso-ionic compounds (1957)

The first page of this article is displayed as the abstract.
Five-year cancer cure: Relation to total amount of peripheral lymphocytes and neutrophils (1970)

An analysis is made of the correlation existing between curability, by conventional treatment, of 589 cases of different types of cancer with reasonable possibilities of cure, and the total number of leukocytes in peripheral blood. A positive significant correlation is found between cancer curability and the total number of peripheral lymphocytes; a negative correlation is found between the total number of peripheral neutrophils (segmented and nonsegmented) and cancer curability. No correlation is found between curability of cancer and monocytes, eosinophils, or basophils. These findings indicate that the immunologic activity of peripheral lymphocytes may be a favorable factor in the cure of cancer by conventional treatment.
IDSaaS: Intrusion Detection System as a Service in Public Clouds (2012)

In a public cloud computing environment, consumers cannot always just depend on the cloud provider's security infrastructure. They may need to monitor and protect their virtual existence by implementing their own intrusion detection capabilities along with other security technologies within the cloud fabric. Intrusion Detection as a Service (IDSaaS) targets security of the infrastructure level of a public cloud (IaaS) by providing intrusion detection technology that is highly elastic, portable and fully controlled by the cloud consumer. A prototype of IDSaaS is described.
Design techniques for ultra-low voltage sub-threshold circuits and on-chip reliability monitoring. (2009)

University of Minnesota Ph.D. dissertation. October 2009. Major: Electrical Engineering. Advisor: Chris H. Kim. 1 computer file (PDF); xix, 193 pages.
Can antidepressants cause mania and worsen the course of affective illness? (1987)

Several investigators have recently challenged the belief that antidepressants can precipitate mania or rapid cycling between mania and depression. With one exception, there appear to be no placebo-controlled studies of switches into mania in bipolar patients during antidepressant treatment. Patients most likely to switch into mania during antidepressant therapy have probably been excluded from maintenance treatment studies and are probably overrepresented in studies at special research facilities. On balance, the available evidence suggests that some bipolar patients become manic, and a few experience rapid cycling, when they are treated with antidepressants. The prevention of these responses will require further research on risk factors and on the antimanic efficacy of coadministered lithium or other mood stabilizers.
Optimization of two-photon-resonant four-wave mixing: application to 1302-nm generation in mercury vapor (1988)

A detailed model of two-photon-resonant four-wave mixing that includes the consideration of efficiency-limiting processes is presented. The model provides a generally applicable systematic approach for maximizing conversion efficiencies for both exact and near two-photon resonance. For exact two-photon resonance, an interference effect limits efficiency to a value determined by ratios of nonlinear susceptibilities and input intensities. For near two-photon resonance, nonlinear refractive indices limit efficiencies unless input intensities are properly balanced. For the specific case of 130.2-nm generation in Hg, we examine a number of potential additional efficiency-limiting processes, including amplified spontaneous emission, stimulated Raman and hyper-Raman gain, parametric gain, linear absorption, and population transfer. We include isotopic effects and Gaussian-profile beams. From our analysis, we conclude that efficiencies of approximately 10% should be feasible by using collimated light beams in an energy-scalable system.
Improved prediction of antibody V<sub>L</sub>–V<sub>H</sub>orientation (2016)

Antibodies are important immune molecules with high commercial value and therapeutic interest because of their ability to bind diverse antigens. Computational prediction of antibody structure can quickly reveal valuable information about the nature of these antigen-binding interactions, but only if the models are of sufficient quality. To achieve high model quality during complementarity-determining region (CDR) structural prediction, one must account for the VL-VH orientation. We developed a novel four-metric VL-VH orientation coordinate frame. Additionally, we extended the CDR grafting protocol in RosettaAntibody with a new method that diversifies VL-VH orientation by using 10 VL-VH orientation templates rather than a single one. We tested the multiple-template grafting protocol on two datasets of known antibody crystal structures. During the template-grafting phase, the new protocol improved the fraction of accurate VL-VH orientation predictions from only 26% (12/46) to 72% (33/46) of targets. After the full RosettaAntibody protocol, including CDR H3 remodeling and VL-VH re-orientation, the new protocol produced more candidate structures with accurate VL-VH orientation than the standard protocol in 43/46 targets (93%). The improved ability to predict VL-VH orientation will bolster predictions of other parts of the paratope, including the conformation of CDR H3, a grand challenge of antibody homology modeling.
Mechanisms of anterior cruciate ligament neovascularization and ligamentization (1998)

Columbia-Rambouillet cross-bred sheep were used to study the revascularization and ligamentization process of anterior cruciate ligament (ACL) reconstruction over a 6-month period using basic histology, immunohistochemistry, and electron microscopy. The reconstruction technique studied was a quadruple-hamstring, interference screw fixation technique. Further, these specimens, after retrieval at 6, 12, and 26 weeks, were compared with human arthroscopic 'second looks' and with 10 en bloc specimens obtained when a cruciate-sacrificing total knee replacement was performed. The study showed that, with this reconstruction technique, Sharpey's fibers were seen at 6 weeks in both sheep and human specimens. The intratunnel specimens showed proliferative chondrification, then ossification of the matrix. Intra-articular neovascularization, ligamentization, and junction ossification occurred. Myoblasts or smooth muscle cells appear to mediate the ligamentization as evidenced in electron microscopy by proliferate collagen manufacture. These myoblasts were seen in both the healing sheep and human second looks, but not seen in mature ACL grafts or in normal ACLs. At 6 months postoperatively, the sheep ACL reconstruction appeared clinically, histologically, and immunohistochemically indistinguishable from the normal sheep ACL. A correlation of this work with published animal studies in which biomechanical testing was performed and with human 'second looks' would imply that an ACL reconstruction may be vulnerable during this period of neovascularization and ligamentization.
Uniform highly branched polymers by anionic grafting: arborescent graft polymers (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUniform highly branched polymers by anionic grafting: arborescent graft polymersMario Gauthier and Martin MoellerCite this: Macromolecules 1991, 24, 16, 4548–4553Publication Date (Print):August 1, 1991Publication History Published online1 May 2002Published inissue 1 August 1991https://pubs.acs.org/doi/10.1021/ma00016a011https://doi.org/10.1021/ma00016a011research-articleACS PublicationsRequest reuse permissionsArticle Views799Altmetric-Citations227LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Treating obesity. (1991)

consulting and in cross cultural consulting should be available to all health professionals and differs from that in any other communication skills only in emphasis. How many of us have listened to or watched any of our own health education consultations with anyone, let alone with someone from a different culture?
Improved Automatic Keyphrase Extraction by Using Semantic Information (2008)

Keyphrases provide semantic metadata producing an overview of the content of a document, they are used in many text-mining applications. This paper proposes a new method that improves automatic keyphrase extraction by using semantic information of candidate keyphrases. Our method is realized in two stages. In selecting candidates stage, after extraction of all phrases from document, a word sense disambiguation method is used to get senses of phrases, then term conflation is performed by using case folding, stemming, and semantic relatedness between candidates. In filtering stage, four features are used to compute for each candidate: the TFxIDF measure describing the specificity of a phrase, first occurrence of a phrase in the document, length of a phrase, and coherence score which measure the semantic relatedness between the phrase and other candidates. A Naive Bayes scheme builds a prediction model training data with known keyphrases, and then uses the model to calculate the overall probability for each candidate. We evaluate semantically improved method against the well known Kea system by using a more effective semantically enhanced evaluation method. The inter-domain experiment shows that quality of keyphrases extraction can be improved significantly when semantic information is exploited. The intra-domain experiment shows our method is competitive with Kea++ algorithm, and not domain-specific.
Magnesium stearate: an underestimated allergen. (2013)

Magnesium stearate is a substance often used as a diluent in the manufacture of medical tablets, capsules and powders. Moreover it is usually found as a food additive or pharmaceutical excipient. We report the first case of a 28 years old woman affected by an allergic reaction from this substance with an urticarial manifestation.
Bioconversion of Barex 210 (an acrylonitrile copolymer) nitrogen for plant utilization (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBioconversion of Barex 210 (an acrylonitrile copolymer) nitrogen for plant utilizationTodd D. Van Gordon and Seymour G. GilbertCite this: J. Agric. Food Chem. 1976, 24, 4, 823–824Publication Date (Print):July 1, 1976Publication History Published online1 May 2002Published inissue 1 July 1976https://pubs.acs.org/doi/10.1021/jf60206a049https://doi.org/10.1021/jf60206a049research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts