gebhart/patrepeval huggingface dataset:
Review of Phosphate Mobility and Persistence in 10 Septic System Plumes (1998)

Abstract Phosphate distribution was reviewed in 10 mature, highly monitored septic system ground water plumes in central Canada. It was shown that six plumes (primarily those on calcareous sands) of enriched P concentrations (0.5 to 5 mg/L P) exceeding 10 m in length are present. In each case, phosphate migration velocity is highly retarded (retardation factor, 20 to 100) compared to the ground water velocity, hut migration rates remain sufficiently fast (−1 m/a) to the of concern when considering long‐term operation and the normal setback distance of septic systems from adjacent surface water bodies (∼ 15 m). Much smaller scale phosphate plumes (< 3 m in length) are present at the acidic sites on noncalcareous sands and on silt‐ and clay‐rich sediments. At all of the sites, ground water concentrations are lower than effluent values by amounts ranging from 23 to 99%, suggesting that P accumulation has occurred in the vadose zone. This was confirmed by sediment analyses at four of the sites which, in each case, showed that zones of Penrichment were present within 1 m of the infiltration pipes (Wood 1993; Zanini et al. 1998). Also, observed phosphate concentrations are generally consistent with values expected based on the solubility constraints of the minerals vivianite in reducing zones (including the septic tank), and strengite and variscite in oxidizing zones, providing further evidence that min‐eral precipitation reactions play a role in limiting P concentrations. Strengite and variscite have the potential to limit P to low con‐centrations (co.1 mg/L) under acidic conditions, but oxidation of sewage efiluent leads to acidic conditions only in noncalcareous terrain or beneath old septic systems where calcium carbonate has been depleted. Overall, phosphate plume migration velocities in ground water appear to be controlled by sorption processes, but the phosphate concentrations that are present in the plumes appear to be strongly controlled by mineral precipitation reactions that occur in close proximity to the infiltration pipes.
Voltage-current characteristics of the electrotactile skin-electrode interface (2003)

Experimental results showing that the static skin-electrode resistance decreases nonlinearly with increasing stimulation current during electric stimulation of the sense of touch are reported. A mathematical model that describes the electrotactile skin-electrode interface is presented. The voltage versus time response of an electrode stimulation with constant-current pulses is also modeled, and two possible explanations for this characteristic are provided.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
PREFATORY NOTE (2009)

THE present volume contains Grace Book Γ, the third of the Grace Books preserved in the Registry of the University. The earlier Grace Books, A and B, have already appeared, in three volumes, in the series published in commemoration of Henry Richards Luard, D.D., Fellow of Trinity College, and Registrary of the University from 1862 to 1891, but, as the present and future volumes will be published by the Syndics of the Cambridge University Press instead of by the Cambridge Antiquarian Society, the connection with Dr Luard's name will no longer be maintained.
Implementation of a Statewide System for Coronary Reperfusion for ST-Segment Elevation Myocardial Infarction (2007)

A statewide program focused on regional systems for reperfusion for STEMI can significantly improve quality of care. Further research is needed to ensure that programs that result in improved application of reperfusion treatments will lead to reductions in mortality and morbidity from STEMI.
The effect of adjuvants and prior immunization on the rate and mode of uptake of antigen into afferent popliteal lymph from sheep. (1985)

Experiments were carried out to determine the effect of a range of adjuvants on the antibody response of sheep to a subcutaneous injection of ovalbumin. Incomplete Freund's adjuvant (IFA) was the best of the repository type adjuvants. From a range of soluble immunopotentiating substances tested, the polyion DEAE-dextran, or dextran sulphate, produced the greatest enhancement of the response. These results were confirmed in a factorial experiment, but no interactions were found between various classes of adjuvants. Further experiments were carried out to determine the effect of superior adjuvants, prior immunization or intradermal injection on the rate and mode of uptake of antigen from the injection site to afferent lymph. These experiments showed that, with IFA, most antigen is retained at the injection site, less than 15% entering lymph by 3 days. There was some delay in antigen uptake with adjuvant 65, while for aluminium phosphate precipitated antigen, the rate of uptake was the same as following a saline injection. There was some delay in uptake of antigen following injection with DEAE-dextran or in primed sheep but, following intradermal injection, the rate of uptake into lymph was the same as aqueous antigen injected subcutaneously. Experiments in which the distribution of radioactive antigen between cells and plasma in lymph was examined showed that, in unprimed sheep, virtually all antigen is unassociated with cells. In primed sheep, however, about 0.5% of antigen in lymph was found to be cell-associated. Gel filtration of lymph plasma from primed sheep demonstrated that nearly all the antigen in lymph is carried to the node as high molecular weight material, presumably antigen-antibody complexes.
Beatrice and the Poetry of Dante (1943)

In sketching the portrait of Virgil I have tried to show the earthly reality, the humanity, naturally imperfect, that belongs to him and confers upon him his corresponding poetical perfection. He germinates from the stratum of everyday experience, the kind that anyone can have with his contemporaries, and if the person enjoying such experience is a great poet the result is a poetical figure like that of Dante's Virgil. Exactly the opposite happens in the case of Beatrice. She had to be from the beginning something supernatural, something perfect, not earthly but celestial. She was not to resemble the young woman of Florence whose name she bore: she was to be as different from the latter as an angel is different from a woman. We shall have to see whether the poet succeeded as well in creating a woman on the plane of the other world as he did in creating a man grown in the soil of earthly experience.
The Web and distance learning: what is appropriate and what is not (1997)

The World Wide Web is increasingly being used to provide opportunities for distance learning. This report explores the motivations for developing Web-based distance learning and examines a range of issues including ethics, pedagogy, planning, advantages, disadvantages, and appropriate and inappropriate uses. The analysis takes a learner-centric view, classing as appropriate those uses of the Web that further the traditional educational values of quality, outreach, and flexibility. Examples of inappropriate uses are also given.
GIPC Binds to the Human Lutropin Receptor (hLHR) through an Unusual PDZ Domain Binding Motif, and It Regulates the Sorting of the Internalized Human Choriogonadotropin and the Density of Cell Surface hLHR (2003)

By using a yeast two-hybrid screen we identified GIPC (GAIP-interacting protein C terminus), a protein with a type I PDZ domain as a novel human lutropin receptor (hLHR) binding partner. Pull-down and immunoprecipitation assays confirmed this interaction and showed that it is dependent on the PDZ domain of GIPC and the C-terminal tetrapeptide of the hLHR. To characterize the functional consequences of the GIPC-hLHR interaction, we used a small interfering RNA against GIPC to generate a clonal cell line that is deficient in GIPC. Studies with this cell line reveal that GIPC is partially responsible for the recycling of the hormone that is internalized by the hLHR and also for maintaining a relatively constant level of hLHR at the cell surface during hormone internalization.
Light and thermal-stimuli responsive materials (2008)

Stimuli-responsive materials exhibit abrupt physical or chemical property changes in response to changes in external stimuli such as light, temperature, pH, as well as ion strengths or exposure to an electric field or magnetic field. In this paper, the progress of light-stimuli responsive materials and thermally stimuli responsive materials are reviewed. The research of light-stimuli responsive materials in the fields of light responsive hydrogels and photochromic materials are described. The progress and applications about thermally sensitive hydrogels, thermally sensitive shape memory materials and thermochromic materials are introduced. The prospects of the application and research of these materials in multi- subject area are also recommended.
Alterations in glycosaminoglycans in wounded skin of diabetic rats. A possible role of IGF-I, IGF-binding proteins and proteolytic activity. (1996)

In the skin of diabetic animal tissues the amount of extracellular matrix (ECM) components is drastically decreased as a result of a reduced rate of their biosynthesis or increased degradation. In the present study we have investigated the mechanism of poor wound healing in diabetic rats. We have found that wounded skin of diabetic rats shows a significant decrease in glycosaminoglycan (GAG) content compared to that of control animals. This decrease was accompanied by significant depletion of insulin-like growth factor-I (IGF-I), known as a stimulator of GAG biosynthesis, and a distinct decrease in the content of high molecular weight IGF-binding proteins (HMW-BPs) with a simultaneous increase in low molecular weight IGF-binding proteins (LMW-BPs) in the sera of diabetic animals. Basing on determination of proteolytic activities we suggest that insulin shortage in diabetes results in increased proteolytic activity in various tissues. Proteolytic enzymes may cleave the HMW-BPs and convert them to LMW-BPs. The LMW-BPs may inactivate IGF-I and eliminate its stimulatory effects on GAG biosynthesis. The proteolytic enzymes may also digest the protein cores of proteoglycans releasing the GAGs and making them more susceptible to the action of glycosidases. These phenomena may be responsible for the observed marked decrease in GAG content in the skin of diabetic rats and disturb the wound-healing process.
Novel in vitro system for functional assessment of oxytocin action (2006)

One of the classical biological actions mediated by the posterior pituitary hormone oxytocin (OT) is contraction of the uterus at parturition. Moreover, premature activation of the OT system is thought to contribute to preterm labor, a major clinical problem in obstetrical practice. However, the molecular mechanisms linking activation of the OT receptor (OTR) to myometrial contractions are not fully understood. Here, we describe an in vitro system that should serve as a useful tool to study this question at a cellular level. The system consists of a collagen lattice contraction assay and two different human myometrial cell lines: a cell clone from a telomerase-immortalized human myometrial cell population (hTERT-C3) as well as a cell line derived from a primary culture of human myometrial cells (M11). Using this approach, we observed that 1 nM OT promoted an almost maximal effect on cell contraction in both cell lines tested. Furthermore, this dose-dependent, OT-induced contraction was antagonized by the specific OTR antagonist d(CH(2))(5)[Tyr(Me)(2),Thr(4),Tyr-NH(2)(9)]OVT as well as the clinically used antagonist atosiban. This cell line-based contraction assay enables the application of molecular tools aimed at suppressing or overexpressing specific genes. It is also amenable to high-throughput testing approaches. Therefore, this system represents a powerful and improved experimental model that should facilitate the study of the molecular signal transduction pathways involved in the uterotonic actions of OT.
Atom microscopy via two-photon spontaneous emission spectroscopy (2009)

We study subwavelength position measurement via spontaneous emission spectroscopy with two photons. Our model systems are a single $\ensuremath{\Lambda}$-type three-level atom, in which a dual interaction generates two independent photons, and an $M$-type five-level atom, which emits two photons in a double-Raman process. The difference is that the $M$-type system emits correlated pairs of photons, while the photon pairs from the $\ensuremath{\Lambda}$ system are uncorrelated. In order to evaluate the performance of the position measurement, we introduce an analysis scheme motivated by a possible experimental measurement procedure. We find characteristic differences in the spontaneous emission spectra of the two systems arising from the photon correlation in the $M$-type system. But interestingly, the effect of this photon pair correlation on the conditional position probability distribution does not lead to an increase in the position information of the single atom. Nevertheless, both schemes allow for an efficient measurement of the particle position with unambiguous position determination over a wide range of parameters.
Efficient Microwave-Assisted Esterification Reaction Employing Methanesulfonic Acid Supported on Alumina as Catalyst (2014)

A rapid and efficient protocol assisted by microwave irradiation for the synthesis of esters using methanesulfonic acid (CH<sub>3</sub>SO<sub>3</sub>H) supported on Al<sub>2</sub>O<sub>3</sub> (AMA) as catalyst and free of solvent is described. The products were obtained in good yields and purity, with reduced reaction time, and the process is simple and environmentally benign.
Beneficial Effects of the Sigma-1 Agonist Fluvoxamine for Tardive Dyskinesia in Patients With Postpsychotic Depressive Disorder of Schizophrenia (2012)

Recently, the sigma-1 receptor agonist fluvoxamine has been considered beneficial for various neuropsychiatric disorders. However, data about the effects of fluvoxamine on hyperkinetic movement disorders are limited. In this report, we attempted to demonstrate the beneficial effects of fluvoxamine on TD, and we suggest that the mechanism of action might be due to sigma-1 agonism. Further detailed, double-blind studies should clarify the potential use of fluvoxamine in the treatment of hyperkinetic movement disorders.
ChemInform Abstract: Transannular Cyclizations of 1,2‐Dithia‐5,8‐diazacyclodeca‐4,8‐dienes During Borohydride Reduction. (1987)

Abstract Treatment of the dithiadiazacyclododecadienes (Ia) ‐ (Id) with sodium borohydride yields only minor amounts of the corresponding monocyclic products (II), the main products are the isomeric imidazolidinodithiazepines (III) and (IV).
Troponin and Cardiac Events in Stable Ischemic Heart Disease and Diabetes (2015)

The cardiac troponin T concentration was an independent predictor of death from cardiovascular causes, myocardial infarction, or stroke in patients who had both type 2 diabetes and stable ischemic heart disease. An abnormal troponin T value of 14 ng per liter or higher did not identify a subgroup of patients who benefited from random assignment to prompt coronary revascularization. (Funded by the National Institutes of Health and Roche Diagnostics; BARI 2D ClinicalTrials.gov number, NCT00006305.).
Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography (2002)

Electron tomography of vitrified cells is a noninvasive three-dimensional imaging technique that opens up new vistas for exploring the supramolecular organization of the cytoplasm. We applied this technique to Dictyostelium cells, focusing on the actin cytoskeleton. In actin networks reconstructed without prior removal of membranes or extraction of soluble proteins, the cross-linking of individual microfilaments, their branching angles, and membrane attachment sites can be analyzed. At a resolution of 5 to 6 nanometers, single macromolecules with distinct shapes, such as the 26S proteasome, can be identified in an unperturbed cellular environment.
Regenerating-mode low-speed operation of sensorless induction motor drive with adaptive observer (2002)

Speed estimation methods for sensorless induction motor drives can be divided into two groups. One is based on information about fundamental components of stator currents and voltages. The other is based on high-frequency components injection in stator voltages or currents. The latter may operate stably under zero frequency, which occurs in regenerating mode at low speeds. It, however, causes loss increasing and torque ripple. The former is difficult to operate under zero frequency. The authors propose a stable method categorized in the former group even in regenerating mode at low speeds. The proposed method is based on an adaptive flux observer. First, a new observer gain design is shown. Next, a method avoiding zero-frequency operation with controlling a rotor flux level is proposed.
Synthesis and Luminescence of Soluble <i>m</i><i>eso-</i>Unsubstituted Tetrabenzo- and Tetranaphtho[2,3]porphyrins (2005)

[Structure: see text]. Syntheses of soluble tetrabenzoporphyrins (TBP) and tetranaphtho[2,3]porphyrins (TNP), with multiple substituents in the conjugated aromatic rings but bearing no substituents in the meso-positions, is reported. Both types of porphyrins were obtained by direct aromatization of precursor porphyrins, annealed with either cyclohexene or dihydronaphthalene fragments. TBPs and TNPs possess powerful absorption bands in the near-infrared (lambda = 610-710 nm, epsilon = 100,000-300,000 M(-1) cm(-1)) and exhibit strong luminescence. Free bases and Zn complexes fluoresce with quantum yields of up to 50%, whereas Pd and Pt complexes phosphoresce in solutions at ambient temperatures. Remarkably, the phosphorescence quantum yields of Pd and Pt TBPs reach as high as 20-50%, which places them among the brightest near-infrared phosphors known to date.
Resistance to nodulation of cv. Afghanistan peas is overcome by <i>nodX</i>, which mediates an O‐acetylation of the <i>Rhizobium leguminosarum</i> lipo‐oligosaccharide nodulation factor (1993)

Only some strains of Rhizobium leguminosarum biovar viciae can efficiently nodulate varieties of peas such as cv. Afghanistan, which carry a recessive allele that blocks efficient nodulation by most western isolates of R.I. viciae. One strain (TOM) which can nodulate cv. Afghanistan peas has a gene (nodX) that is required to overcome the nodulation resistance. Strain TOM makes significantly lower amounts of lipo-oligosaccharide nodulation factors than other strains of R.I. viciae and this effect appears to be due to lower levels of nod gene induction. These nodulation factors are similar to those from other R.I. viciae strains in that they consist of an oligomer of four or five beta 1-4-linked N-acetylglucosamine residues in which the terminal non-reducing glucosamine carries an O-acetyl group and a C18:4 or C18:1 N-acyl group. However, one of the nodulation factors made by strain TOM differs from the factors made by other strains of R.I. viciae in that it carries an O-acetyl group on the C-6 of the reducing N-acetylglucosamine residue. This acetylation is NodX-dependent and the pentameric nodulation factor is acetylated on the reducing N-acetylglucosamine residue whereas the tetrameric nodulation factor is not. Although the nodL gene product is also an O-acetyl transferase (it O-acetylates the C-6 of the terminal non-reducing glucosamine), there is very little similarity between the amino acid sequences of these two acetyl transferases.
Identification, molecular cloning and expression of an Î±-<i>N</i>-acetylgalactosaminidase gene from<i>Clostridium perfringens</i> (2002)

The Clostridium perfringens gene encoding the previously characterized alpha-N-acetylgalactosaminidase (alphaNAG) was identified by protein microsequencing and database searching. The alphaNAG protein, designated AagA, was found to be encoded by a hypothetical gene of unknown function in the recently completed genome sequence of C. perfringens strain 13. The deduced translation product of 629 amino acid residues possessed a region of limited homology to several hypothetical open reading frames, an enterotoxin of unknown function and several known or predicted alpha-galactosidases, but did not exhibit homology to any of the multiple sequenced eukaryotic alphaNAG proteins. The C. perfringens aagA gene, encoding AagA, was cloned in an Escherichia coli T7 expression system, resulting in recombinants exhibiting high-level expression of the expected alphaNAG activity. To our knowledge, this is the first report of the cloning and expression of a bacterial alphaNAG-encoding gene and represents an important step in the development of recombinant alphaNAG as a tool in the enzymatic conversion of blood group antigens.
Propagation over buildings for paths oblique to the street grid (2003)

Prediction of cell shape is important for proposed microcellular systems employing base station antennas at or below the surrounding rooftops. For residential and commercial areas, where the buildings are of nearly uniform height, prediction of cell shape will require knowledge of how the average signal received by street level mobiles depends on the direction of propagation relative to the rows of buildings. This paper presents theoretical results for the signal dependence on direction of propagation, number of intervening rows of buildings and the base station antenna height. Assuming all buildings to be of equal heights, the range dependence of the average signal is found by evaluating multiple forward diffraction past rows of buildings, perpendicular or oblique to the propagation path. These theoretical results are compared with measurements.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A dopant-free organic hole transport material for efficient planar heterojunction perovskite solar cells (2015)

Planar heterojunction perovskite solar cells using a dopant-free organic hole transport material have been developed and an efficiency of 14.9% has been demonstrated.
Configuration and Estimation Cost of the flying platform HeliPlat (2003)

HELINET Reports Number HE-068-A1A-POL-RP-05 Nota Scientifica e Tecnica 231, DIASP Politecnico di Torino, Dicembre 2003
A closed-loop logistics model for remanufacturing (1999)

Recoverable product environments are becoming an increasingly important segment of the overall push in industry towards environmentally conscious manufacturing. Integral to the recoverable product environment is the recoverable manufacturing system that focuses on recovering the product and extending its life through remanufacture or repair. Remanufacturing provides the customer with an opportunity to acquire a product that meets the original product standards at a lower price than a new product. The flow of materials and products in this environment occurs both from the customer to the remanufacturer (reverse flow), and from the remanufacturer to the customer (forward flow). Since most of the products and materials may be conserved, essentially this forms a closed-loop logistics system. We present a 0–1 mixed integer programming model that simultaneously solves for the location of remanufacturing/distribution facilities, the transshipment, production, and stocking of the optimal quantities of remanufactured products and cores. We also discuss the managerial uses of the model for logistics decision-making.