gebhart/patrepeval huggingface dataset:
The Sealed Nickel‐Hydrogen Secondary Cell (1975)

A recently developed sealed nickel‐hydrogen cell offers considerable promise to develop lightweight, long‐life, rechargeable batteries. The most apparent advantages of this cell are its higher energy and power density as compared with other rechargeable systems including nickel‐cadmium, lead‐acid, and silver‐zinc cells and the regenerative fuel cell. The energy density for lightweight 50 A‐hr cells shown is 28 W‐hr/lb. The cell enjoys a unique overdischarge protection mechanism which allows for long cycle life at high depth of discharge. Experimental data are presented to define the characteristics of the cell. Over 5000 high rate cycles have been completed on small 1.5 A‐hr cells with good voltage performance. A 50 A‐hr cell has completed to date over 800 cycles discharge to 70% of measured capacity in 1.2 hr.
Correlating the Structural and Photophysical Features of Pincer Luminophores and Monodentate Ancillary Ligands in Pt<sup>II</sup> Phosphors (2015)

Abstract Phosphorescent Pt II complexes featuring pincer luminophores of 2,6‐bis(1,2,4‐triazolyl)pyridine (H 2 L1 ) and 2,6‐bis(pyrazolyl)pyridine (H 2 L3 ) with a bulky adamantyl or tolyl substituent (H 2 L4 ) are systematically compared, and their structural features are correlated with their photophysical properties. The combination with 4‐amylpyridine (Py), triphenylphosphine (P) or benzimidazol‐2‐ylidene (N‐heterocyclic carbene, NHC) donors as monodentate ancillary ligands gave a series of highly luminescent triplet emitters with variable aggregation properties. The molecular structures of four of these complexes, namely, Pt‐ L1 ‐P, Pt‐ L1 ‐NHC, Pt‐ L3 ‐P, and Pt‐ L4 ‐P were garnered from single‐crystal X‐ray diffraction analysis. The coordination complexes displayed green phosphorescence in solution and in the solid state. In doped poly(methyl methacrylate) (PMMA) matrices, most of the complexes exhibited high phosphorescence quantum yields, which reached 59 % for Pt‐ L3 ‐P. A comparative analysis between the spectroscopic data and the computed parameters derived from time‐dependent density functional theory (TD‐DFT) calculations suggests that the emission originates from metal‐perturbed ligand‐centered excited triplet states ( 3 MP‐LC). The radiationless deactivation rate constants of the emissive states can be correlated with the aggregation properties derived from the substitution pattern at the tridentate luminophores and the ancillary ligands, whereas the radiative rate constants are determined by the electronic structures of the complexes. We found that Pt II complexes containing pyrazolate donors showed an enhanced charge‐transfer character in the excited state, whereas bulky adamantyl moieties and triphenylphosphine ancillary ligands suppress bimolecular aggregation and quenching phenomena.
In vitro protein translocation into inverted membrane vesicles prepared from <i>Vibrio alginolyticus</i> is stimulated by the electrochemical potential of Na<sup>+</sup> in the presence of <i>Escherichia coli</i> SecA (1990)

A protein translocation system was reconstituted from inverted membrane vesicles prepared from Na+ pump-possessing Vibrio alginolyticus and purified Escherichia coli SecA. The translocation required ATP and was stimulated by the functioning of the Na+ pump, suggesting that the electrochemical potential of Na+, but not that of H+, is important for protein translocation in Vibrio.
Domain-independent data cleaning via analysis of entity-relationship graph (2006)

In this article, we address the problem of reference disambiguation . Specifically, we consider a situation where entities in the database are referred to using descriptions (e.g., a set of instantiated attributes). The objective of reference disambiguation is to identify the unique entity to which each description corresponds. The key difference between the approach we propose (called RelDC) and the traditional techniques is that RelDC analyzes not only object features but also inter-object relationships to improve the disambiguation quality. Our extensive experiments over two real data sets and over synthetic datasets show that analysis of relationships significantly improves quality of the result.
Peer-to-Peer Secure Multi-party Numerical Computation (2008)

We propose an efficient framework for enabling secure multi-party numerical computations in a Peer-to-Peer network. This problem arises in a range of applications such as collaborative filtering, distributed computation of trust and reputation, monitoring and numerous other tasks, where the computing nodes would like to preserve the privacy of their inputs while performing a joint computation of a certain function. Although there is a rich literature in the field of distributed systems security concerning secure multi-party computation, in practice it is hard to deploy those methods in very large scalePeer-to-Peer networks. In this work, we examine several possible approaches and discuss their feasibility. Among the possible approaches, we identify a single approach which is both scalable and theoretically secure. An additional novel contribution is that we show how to compute the neighborhood based collaborative filtering, a state-of-the-art collaborative filtering algorithm, winner of the Netflix progress prize of the year 2007. Our solution computes this algorithm in a Peer-to-Peer network, using a privacy preserving computation, without loss of accuracy. Using extensive large scale simulations on top of real Internet topologies, we demonstrate the applicability of our approach. Asfar as we know, we are the first to implement such a large scale secure multi-party simulation of networks of millions of nodes and hundreds of millions of edges.
Manganese biofouling and the corrosion behavior of stainless steel (1996)

Manganese- and iron-oxidizing bacteria (MFOB) are widely implicated in microbially influenced corrosion, often in association with sulfate-reducing bacteria (SRB). Traditionally MFOB have been assigned a passive role in the corrosion process, promoting differential aeration cells, and providing oxygen depleted conditions conducive to the growth and corrosive attack of SRB. Recent work, summarized in this article, demonstrates that manganese biofouling alters the electrochemical behavior of stainless steel (SS), and suggests that MFOB are more active in localized corrosion than traditionally held. The paper discusses the chemistry and potentially corrosive impact of manganese and iron oxides on SS, explores the possible relationship between MFOB and SRB, and proposes a model to describe the synergistic influence these organisms may exert in the corrosion process.
Oxygen deficiency hazards associated with liquefied gas systems development of a program of controls (1983)

The use of liquefied gases in industry and research has become commonplace. Release into the atmosphere of these gases, whether intentional or not, will result in a displacement of air and a reduction in the oxygen concentration. Exposure to reduced levels of oxygen levels may cause reduced abilities, unconsciousness, or death. This paper describes the derivation of a novel program of controls for oxygen deficiency hazards. The key to this approach is a quantitative assessment of risk for each planned operation and the application of control measures to reduce that risk to an acceptable level. Five risk levels evolve which are based on the probability of fatality. Controls such as training, oxygen monitoring equipment, self-rescue respirators, and medical surveillance are required when the probability of fatality exceeds 10/sup -7/ per hour. The quantitative nature of this program ensures an appropriate level of control without undue burden or expense. 11 references, 5 figures, 3 tables.
In Situ Observation of Dithiocarbamate-Based Surface Photograft Copolymerization Using Quartz Crystal Microbalance (1999)

A quartz crystal microbalance (QCM) technique which can detect weight increase in the nanogram order has been employed to continuously monitor the iniferter-based surface photograft polymerization behavior of vinyl monomers. The gold electrodes of the QCM were thinly coated with a photoreactive polystyrene partially derivatized with N,N-diethyldithiocarbamylmethyl groups acting as iniferters. A monotonic decrease in the resonance frequency of the vibrating oscillator of QCM, which was correlated with the weight increase via graft copolymerization initiated on the polystyrene, occurred immediately after ultraviolet light irradiation of the coated electrode surface in a methanolic or aqueous solution of vinyl monomers such as acrylamide (AAm), N,N-dimethylacrylamide (DMAAm), methacrylamide (MAm), methacrylic acid (MA), ethyl acrylate (EA), 2-hydroxyethyl methacrylate (HEMA), 2-(dimethylamino)ethyl methacrylate (DMAEM), N-vinyl-2-pyrrolidone (VP), and styrene (ST), except for vinyl acetate (VA). Upon cessation of irradiation, little frequency change was observed. The cycle comprising a decrease in resonance frequency under irradiation and no change under dark condition was repeated without appreciable fatigue. The polymer yield showed an almost linear increase with irradiation time up to 20 min. The apparent polymerization rate increased with concentration of monomer, light intensity, and surface density of dithiocarbamate groups. In addition, the rate was dependent on monomer's Q value and maximum at Q values of around 0.7−0.8 for EMA and HEMA.
Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection (2011)

The interaction of antibodies, dengue virus (DENV), and monocytes can result in either immunity or enhanced virus infection. These opposing outcomes of dengue antibodies have hampered dengue vaccine development. Recent studies have shown that antibodies neutralize DENV by either preventing virus attachment to cellular receptors or inhibiting viral fusion intracellularly. However, whether the antibody blocks attachment or fusion, the resulting immune complexes are expected to be phagocytosed by Fc gamma receptor (FcγR)-bearing cells and cleared from circulation. This suggests that only antibodies that are able to block fusion intracellularly would be able to neutralize DENV upon FcγR-mediated uptake by monocytes whereas other antibodies would have resulted in enhancement of DENV replication. Using convalescent sera from dengue patients, we observed that neutralization of the homologous serotypes occurred despite FcγR-mediated uptake. However, FcγR-mediated uptake appeared to be inhibited when neutralized heterologous DENV serotypes were used instead. We demonstrate that this inhibition occurred through the formation of viral aggregates by antibodies in a concentration-dependent manner. Aggregation of viruses enabled antibodies to cross-link the inhibitory FcγRIIB, which is expressed at low levels but which inhibits FcγR-mediated phagocytosis and hence prevents antibody-dependent enhancement of DENV infection in monocytes.
Drug-induced renal disorders. (2015)

Drug-induced nephrotoxicity are more common among infants and young children and in certain clinical situations such as underlying renal dysfunction and cardiovascular disease. Drugs can cause acute renal injury, intrarenal obstruction, interstitial nephritis, nephrotic syndrome, and acid-base and fluid electrolytes disorders. Certain drugs can cause alteration in intraglomerular hemodynamics, inflammatory changes in renal tubular cells, leading to acute kidney injury (AKI), tubulointerstitial disease and renal scarring. Drug-induced nephrotoxicity tends to occur more frequently in patients with intravascular volume depletion, diabetes, congestive heart failure, chronic kidney disease, and sepsis. Therefore, early detection of drugs adverse effects is important to prevent progression to end-stage renal disease. Preventive measures requires knowledge of mechanisms of drug-induced nephrotoxicity, understanding patients and drug-related risk factors coupled with therapeutic intervention by correcting risk factors, assessing baseline renal function before initiation of therapy, adjusting the drug dosage and avoiding use of nephrotoxic drug combinations.
Building a Private HPC Cloud for Compute and Data-Intensive Applications (2013)

Traditional HPC (High Performance Computing) clusters are best suited for well-formed calculations. The orderly batch-oriented HPC cluster offers maximal potential for performance per application, but limits resource efficiency and user flexibility. An HPC cloud can host multiple virtual HPC clusters, giving the scientists unprecedented flexibility for research and development. With the proper incentive model, resource efficiency will be automatically maximized. In this context, there are three new challenges. The first is the virtualization overheads. The second is the administrative complexity for scientists to manage the virtual clusters. The third is the programming model. The existing HPC programming models were designed for dedicated homogeneous parallel processors. The HPC cloud is typically heterogeneous and shared. This paper reports on the practice and experiences in building a private HPC cloud using a subset of a traditional HPC cluster. We report our evaluation criteria using Open Source software, and performance studies for compute-intensive and data-intensive applications. We also report the design and implementation of a Puppet-based virtual cluster administration tool called HPCFY. In addition, we show that even if the overhead of virtualization is present, efficient scalability for virtual clusters can be achieved by understanding the effects of virtualization overheads on various types of HPC and Big Data workloads. We aim at providing a detailed experience report to the HPC community, to ease the process of building a private HPC cloud using Open Source software.
Voluntary movements for robotic control (1992)

A neuromuscular-like nonlinear mathematical model for controlling robotic limbs is described. The model consists of two muscle-reflex models representing a pair of muscles acting as an agonist and an antagonist in moving a load. The responses of the model have been compared with experimental data from human wrist movements in order to identify command signals in the form of a series of rectangular pulses for effecting the measured movements with two different loads. These results can be used to obtain several empirical rules for muscle modulation control. The proposed control strategy can also compensate for unexpected disturbances, which is an essential capability for compliance control.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Presence of N-Unsubstituted Glucosamine Units in Native Heparan Sulfate Revealed by a Monoclonal Antibody (1995)

Immunohistochemical application of antibodies against heparan sulfate proteoglycan core protein and heparitinase-digested heparan sulfate stubs showed the presence of heparan sulfate proteoglycan in all basement membranes of the rat kidney. However, a monoclonal antibody (JM-403) against native heparan sulfate (van den Born, J., van den Heuvel, L. P. W. J., Bakker, M. A. H., Veerkamp, J. H., Assmann, K. J. M., and Berden, J. H. M. (1992) Kidney Int. 41, 115-123) largely failed to stain tubular basement membranes, suggesting the presence of heparan sulfate chains lacking the specific JM-403 epitope. Heparan sulfate preparations from various sources differed markedly with regard to JM-403 binding, as demonstrated by liquid phase inhibition in enzyme-linked immunosorbent assay, the interaction decreasing with increasing sulfate contents of the polysaccharide. Mapping of the JM-403 epitope indicated that it was dominated by one or more N-unsubstituted glucosamine unit(s), since treatments that destroyed or altered the structure of such units in heparan sulfate preparations (cleavage at N-unsubstituted glucosamine units with HNO2 at pH 3.9 and N-acetylation with acetic anhydride, respectively), abolished antibody binding. Conversely, immunoreactivity could be induced in a (D-glucuronyl-1,4-N-acetyl-D-glucosaminyl-1,4) polysaccharide by the generation of N-unsubstituted glucosamine N-unsubstituted glucosamine in a JM-403-binding heparan sulfate (preparation HS-II from human aorta) was demonstrated by an approximately 3-fold reduction in molecular size following HNO2 (pH 3.9) treatment. Further characterization of the epitope recognized by JM-403, based on enzyme-linked immunosorbent assay inhibition tests with chemically/enzymatically modified polysaccharides, indicated that one or more N-sulfated glucosamine units are invariable present, whereas L-iduronic acid and O-sulfate residues appear to inhibit JM-403 reactivity. It is concluded that the epitope contains one or more N-unsubstituted glucosamine and D-glucuronic acid units and is located in a region of the heparan sulfate chain composed of mixed N-sulfated and N-acetylated disaccharide units.
A Solid-Phase Route to <i>N</i>-Cyanoamides (2002)

[reaction: see text] A new method for the solid-phase synthesis of cyanamides is described. The attachment of a secondary amine to solid support is accomplished using Merrifield resin. After functionalization, cleavage is readily achieved with cyanogen bromide to afford the desired cyanamide.
An architecture for more realistic conversational systems (2001)

In this paper, we describe an architecture for conversational systems that enables human-like performance along several important dimensions. First, interpretation is incremental, multi-level, and involves both general and task- and domain-specific knowledge. Second, generation is also incremental, proceeds in parallel with interpretation, and accounts for phenomena such as turn-taking, grounding and interruptions. Finally, the overall behavior of the system in the task at hand is determined by the (incremental) results of interpretation, the persistent goals and obligations of the system, and exogenous events of which it becomes aware. As a practical matter, the architecture supports a separation of responsibilities that enhances portability to new tasks and domains.
The Effect of Detergents on Amino Acid Liberation by the N2-fixing Cyanobacterium Anabaena variabilis and 6-Fluorotryptophan-resistant Mutant Strains (1988)

The effects of the polyoxyethylene stearate detergents MYRJ 45 and MYRJ 52 on FT-9, an amino-acid-liberating mutant strain of Anabaena variabilis, and on the parent strain were investigated. Both strains were capable of growth in the presence of these detergents, which induced the liberation of amino acids by the parent strain and increased the liberation of amino acids by the mutant strain. Some changes in the spectrum of amino acids liberated by the mutant strain were observed in the presence of detergents, notably the liberation of tryptophan, which was not detected in the absence of detergents.
Information retrieval II (1973)

Article Free Access Share on Information retrieval IICSC '73: Proceedings of the 1st annual computer science conference on Program information abstractsFebruary 1973 Pages 61–62https://doi.org/10.1145/1125118.1125153Published:20 February 1973Publication History 0citation41DownloadsMetricsTotal Citations0Total Downloads41Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Crystal structures of RsbQ, a stress‐response regulator in <i>Bacillus subtilis</i> (2005)

Growth-limiting stresses in bacteria induce the general stress response to protect the cells against future stresses. Energy stress caused by starvation conditions in Bacillus subtilis is transmitted to the sigma(B) transcription factor by stress-response regulators. RsbP, a positive regulator, is a phosphatase containing a PAS (Per-ARNT-Sim) domain and requires catalytic function of a putative alpha/beta hydrolase, RsbQ, to be activated. These two proteins have been found to interact with each other. We determined the crystal structures of RsbQ in native and inhibitor-bound forms to investigate why RsbP requires RsbQ. These structures confirm that RsbQ belongs to the alpha/beta hydrolase superfamily. Since the catalytic triad is buried inside the molecule due to the closed conformation, the active site is constructed as a hydrophobic cavity that is nearly isolated from the solvent. This suggests that RsbQ has specificity for a hydrophobic small compound rather than a macromolecule such as RsbP. Moreover, structural comparison with other alpha/beta hydrolases demonstrates that a unique loop region of RsbQ is a likely candidate for the interaction site with RsbP, and the interaction might be responsible for product release by operating the hydrophobic gate equipped between the cavity and the solvent. Our results support the possibility that RsbQ provides a cofactor molecule for the mature functionality of RsbP.
Synthetic oligodeoxynucleotide containing CpG motif induces an anti-polysaccharide type 1-like immune response after immunization of mice with Haemophilus influenzae type b conjugate vaccine (2000)

Synthetic oligodeoxynucleotides containing CpG motifs [immunostimulatory sequences (ISS)] have been described as potent adjuvants of type 1 immune responses when co-administered with protein or peptide vaccines. To investigate their role in the immune response to polysaccharides (CHO), different preparations of anti-Haemophilus influenzae type b (Hib) conjugate vaccine were administered to mice. The unconjugated CHO did not induce the synthesis of specific antibodies even in the presence of ISS. On the other hand, anti-CHO-specific antibodies significantly increased in the presence of ISS, when tetanus (TT) or diphtheria [cross-reacting material (CRM)] toxoid-conjugated CHO were used to immunize mice. The adjuvant effect was also observed for the immune response against the carrier protein (TT and CRM). ISS insured an early and long-lasting specific IgG production. The effects of ISS on the anti-CHO immune response could be attributed to the amplification of the T help provided by the carrier. The analysis of anti-CHO IgG subclasses showed a significant increase of IgG2a and IgG3 in the presence of ISS. ISS caused a rapid release of IL-12 and IFN-gamma in sera from treated mice. This data provide a first evidence for the ability of ISS to induce an anti-CHO type 1-like immune response and demonstrate that ISS have the potential to increase host antibody response against both the CHO and the protein component of a conjugated vaccine.
New E2A/PBX1 fusion transcript in a patient with t(1;19)(q23;p13) acute lymphoblastic leukemia. (1993)

About 25% of the children with pre-B cell acute lymphoblastic leukemia (ALL) have a chromosomal translocation of t(1;19)(q23;p13). This translocation juxtaposes the E2A gene on chromosome 19 to the PBX1 gene on chromosome 1, leading to production of a fusion transcript. The fusion sites of the E2A and PBX1 coding sequence have been identical among all cases of t(1;19) ALL studied so far. Here we described a new fusion site of the E2A and PBX1 genes, which was detected in the leukemic blasts of a child with t(1;19) pre-B ALL using the reverse transcriptase polymerase chain reaction and direct sequencing. The fusion site was located just upstream of the DNA binding domain of the E2A gene, and was close to a homeodomain of the PBX1 gene.