gebhart/patrepeval huggingface dataset:
Group Rehabilitation for Cancer Patients: : Effects, Patient Satisfaction, Utilisation and Prediction of Rehabilitation Need (2003)

The aims are to investigate cancer patients' perceived satisfaction with a Group Rehabilitation (GR) intervention, to evaluate its effects, and to explore the extent to which the patient's coping style (monitoring, blunting) modulates the effects of the GR. An additional aim is to investigate to what extent some aspects of health-related quality of life (HRQOL) [Physical Functioning (PF), Emotional Functioning (EF) and Global Quality of Life (QoL)] one year after diagnosis can be predicted on the basis of medical, socio-demographic and psychological data collected att diagnosis. Patients (n=481) newly diagnosed with breast, gastrointestinal or prostate cancer, were randomly assigned (Support-Care-Rehabilitation project) to one of four alternatives: 1. “Individual Support” (IS) starting at diagnosis; 2. “Group Rehabilitation” (GR) starting approximately four months later; 3. A combination of IS and GR; or 4. Standard Care (SC). All patients were monitored for two years. The GR comprised eight weekly sessions and one booster session after two months. The 2.5 hour meetings dealt with information about cancer, treatment, nutrition, cognitive behavioural therapy (CBT), light physical training and relaxation. Patients rated the physical and informative components as somewhat more beneficial than the CBT component. Meeting others was also rated as beneficial. However, there were limited effects on quality of life and anxiety. The monitoring concept was useful for distinguishing a subgroup of cancer patients (prostate cancer monitors) who benefited from the GR programme. Regression analyses demonstrated that the presence of advanced disease at diagnosis predicted a reduced physical function one year later. Having one or more comorbid conditions predicted lower PF and QoL, EF was predicted only by lower mental well-being and being classified as a case on the basis of the HADS. Indications for offering rehabilitative programs to cancer patients are critically discussed.
Contraception--a look forward, Part III: Inhibin and brain-enhanced estrogen delivery. (1991)

The final installment of this review examines two contraceptive methods, inhibin and brain-enhanced estrogen delivery, which are radically different from any currently available. Inhibin is a gonadal hormone that specifically inhibits pituitary production of follicle-stimulating hormone. Before it was finally isolated in 1985, inhibin was expected to be an ideal contraceptive. Recent research, however, has shown that the inhibin hormonal system is unexpectedly complex, and hopes for clinical use of inhibin must be suspended for the present. Although oral contraception is one of the most effective methods ever devised, use is limited by adverse effects of estrogen (or fears of such effects). A system known as brain-enhanced estrogen delivery specifically delivers estrogen to the brain, including the hypothalamus, there inducing suppression of the gonadotropin-releasing hormone. It has been described and tested in animals, and its successful development could replace current oral contraceptives and extend their availability to many more women.
Gastrulation in the mouse: assessment of cell populations in the epiblast of tw18/tw18 embryos. (1978)

Homozygous tW18 embryos die prior to organogenesis. They develop gross abnormalities shortly after primitive streak formation. Anatomically, the lesion appears to be confined to the mesoderm with that tissue showing ultrastructural deficiencies and abnormal migration (Spiegelman & Bennett, 1974), and failing to develop in teratomas produced from mutant embryos (Artzt & Bennett, 1972). Analysis of growth rate by determining cell number increase, and by mapping mitotic activity and planes of cleavage in the epiblast shows that the mutant embryos are small but paradoxically show overall a very high mitotic activity, approximately double that of their normal litter mates. They also show a marked disorientation of the planes of cleavage in most of the epiblast. In pre-primitive streak embryos, before gross abnormality is detectable, two types of embryo can be found. One group constitutes the small embryos which also show the mitotic disturbances characteristic of the later stage mutants. The second group, larger embryos, do not show mitotic abnormalities. The tW18 allele thus seems to act several hours before primitive streak formation. Since there is no difference in the amount of cell between mutant and normal embryos until 6.75 days p.c. it seems that arrest in division is the cause of the elevated mitotic index in mutants. Significantly a small region of the epiblast in mutant embryos is free of the mitotic abnormalities characteristic of the tissue as a whole. This region is the so-called proliferative zone (Snow, 1977) and the data suggest that it may be from this region that some of the ectoderm of the later embryos is produced.
Evolution of Bordetella pertussis and Bordetella parapertussis under acellular Pertussis vaccine pressure : What future for whooping cough and Pertussis vaccination ? (2014)

Whooping cough is an acute respiratory disease life threatening for unvaccinated young children. It is caused by Bordetella pertussis and Bordetella parapertussis, two gram-negative bacteria restricted to humans. The introduction of vaccination against B. Pertussis in the 1950s greatly changed the epidemiology of pertussis as well as the bacterial population itself. Whole cell vaccines were first introduced for children immunization and first booster and enabled to control isolates similar to strains included in the vaccines. Acellular pertussis vaccines, only targeting few bacterial antigens, were later introduced for adolescent booster vaccination before being generalized to the whole population, including adults and new-borns. In addition to a change in the type of vaccine-induced immunity, B. Pertussis also had to face increased herd immunity. Few years alter acellular pertussis vaccine introduction we demonstrated a temporal increase in the prevalence of isolates lacking the production of one vaccine antigen, pertactin, while the population remained quite monomorphic at the genetic level as compare to the post-whole cell vaccine era (allelic stability of known virulence factors). We characterized these isolates at the phenotypic level and demonstrated that they remain as virulent in different in vitro and in vivo models of host pathogen interaction while they might present a selective advantage in an acellular immunized background targeting pertactin. Although vaccines remain effective, surveillance must continue to follow the evolution of these isolate prevalence and the possible impact of pertactin loss on vaccine effectiveness.
NetDetect: Neighborhood Discovery in Wireless Networks Using Adaptive Beacons (2011)

It is generally foreseen that the number of wirelessly connected networking devices will increase in the next decades, leading to a rise in the number of applications involving large-scale networks. A major building block for enabling self-* system properties in ad-hoc scenarios is the run-time discovery of neighboring devices and somewhat equivalently, the estimation of the local node density. This problem has been studied extensively before, mainly in the context of fully-connected, synchronized networks. In this paper, we propose a novel adaptive and decentralized solution, the NetDetect algorithm, to the problem of discovering neighbors in a dynamic wireless network. The main difference with existing state of the art is that we target dynamic scenarios, i.e., multihop mesh networks involving mobile devices. The algorithm exploits the beaconing communication mechanism, dynamically adapting the beacon rate of the devices in the network based on local estimates of neighbor densities. We evaluate NetDetect on a variety of networks with increasing levels of dynamics: fully-connected networks, static and mobile multi-hop mesh networks. Results show that NetDetect performs well in all considered scenarios, maintaining a high rate of neighbor discoveries and good estimate of the neighborhood density even in very dynamic situations. More importantly, the proposed solution is adaptive, tracking changes in the local environment of the nodes without any additional algorithmic reconfiguration. Comparison with existing approaches shows that the proposed scheme is efficient from both convergence time and energy perspectives.
Measured Results of Phased Shallow and Deep Retrofits in Existing Homes (2014)

The U.S. Department of Energy (DOE) Building America program, in collaboration with Florida Power & Light (FPL), is pursuing a phased residential energy-efficiency retrofit program in Florida. This research is to establish annual energy and peak energy reductions from the technologies of two levels of retrofit ‐ shallow and deep, with savings levels at the high end expected to reduce whole-house energy use by 40%. The Phased Deep Retrofit (PDR) project, has installed staged energy-efficiency retrofits in a sample of 60 existing, all electric homes. 1 Energy end-use savings and economic evaluation results from the phased measure packages and single measures are summarized along with lessons learned. Background
RSEQtools: a modular framework to analyze RNA-Seq data using compact, anonymized data summaries (2010)

RSEQtools is implemented in C and the source code is available at http://rseqtools.gersteinlab.org/.
A Flexible and Portable Multiband GNSS front-end System (2012)

In this paper, the latest version of the Fraunhofer USB front-end development, called the Flexiband, is presented. Thanks to its new modular concept, the Flexiband not only supports a set of pre-selected configurations but can also be set up for multi-antenna inputs, user selectable bandwidth, intermediate frequencies, and customized ADC sampling rates and resolutions. The Flexiband hardware and software components are described in detail. Different configurations are shown and one example of a recorded Galileo E1/E5a signal is analyzed.
Optical mapping of Langendorff-perfused human hearts: establishing a model for the study of ventricular fibrillation in humans (2007)

Our objective was to establish a novel model for the study of ventricular fibrillation (VF) in humans. We adopted the established techniques of optical mapping to human ventricles for the first time to determine whether human VF is the result of wave breaks and singularity point formation and is maintained by high-frequency rotors and fibrillatory conduction. We describe the technique of acquiring optical signals in human hearts during VF, their characteristics, and the feasibility of possible analyses that could be performed to elucidate mechanisms of human VF. We used explanted hearts from five cardiomyopathic patients who underwent transplantation. The hearts were Langendorff perfused with Tyrode solution (95% O(2)-5% CO(2)), and the potentiometric dye di-4-ANEPPS was injected as a bolus into the coronary circulation. Fluorescence was excited at 531 +/- 20 nm with a 150-W halogen light source; the emission signal was long-pass filtered at 610 nm and recorded with a mapping camera. Fractional change of fluorescence varied between 2% and 12%. Average signal-to-noise ratio was 40 dB. The mean velocity of VF wave fronts was 0.25 +/- 0.04 m/s. Submillimetric spatial resolution (0.65-0.85 mm), activation mapping, and transformation of the data to phase-based analysis revealed reentrant, colliding, and fractionating wave fronts in human VF. On many occasions the VF wave fronts were as large as the entire vertical length (8 cm) of the mapping field, suggesting that there are a limited number of wave fronts on the human heart during VF. Phase transformation of the optical signals allowed the first demonstration ever of phase singularity point, wave breaks, and rotor formation in human VF. This method provides opportunities for potential analyses toward elucidation of the mechanisms of VF and defibrillation in humans.
Distribution of Pseudomonas syringae pathovars into twenty-three O serogroups (1996)

Serological reactions of Pseudomonas syringae and Pseudomonas viridiflava were studied by Ouchterlony double diffusion. A total of 55 polyclonal antisera, containing anti-lipopolysaccharide (anti-LPS) precipitating antibodies, were cross-tested against antigenic suspensions of 51 strains. Twenty-three O serogroups were defined, primarily on the reaction of the type strains. Two families of O serogroups showed antigenic crossreactivities (PHA, MOP1, MOP2, MOP3, HEL1, HEL2, and SYR1; PERSAVTOM1, PERSAVTOM2, DEL, POR, and SYR2). Ten O serogroups showed a clearcut specificity: APTPIS, TAB, VIR1, VIR2, VIR3, SYR3, SYR4, SYR5, HUS, and LAC. The last serogroup (RIB) contained strains with rough colony morphology and side chain-deficient LPSs, as evidenced by sodium dodecyl sulfate-polycrylamide gel electrophoresis. The LPS basis of the O serogroups was demonstrated by immunoblotting. Serological reference strains were designated for all of the O serogroups and correspondence was established between the O serogroups studied and seven previous serogroups (L. T. Pastushenko and I.D. Simonovich, Mikrobiol, Zh. 41:222-229 and 330-339, 1979). A total of 355 strains of P. syringae (sensu lato) belonging to 15 pathovars, not including pathovar syringae, were typed into the 23 described O serogroups. O serogroups were assigned after double-diffusion reactions, with each strain compared with serological references. The utility of O serogrouping to study P. syringae pathovar structure and diversity is discussed.
Three-Dimensional Passivated-Electrode Insulator-Based Dielectrophoresis (3D-PiDEP) (2013)

The focus of this research is the isolation of waterborne pathogens which are one of the grand challenges to human health, costing the lives of about 2.5 million people worldwide each year. The aim was to develop new microfluidic techniques for selectively concentrating and detecting waterborne pathogens. Detection of microbes in water can greatly help reduce deaths; however, analytical instruments cannot readily detect them due to the extreme dilution of these microbes, and hence, require significant sample concentration. Current methods are expensive and either require days to process or are not sufficiently robust for water monitoring. Microfluidic chips based on insulator-based dielectrophoresis (iDEP) provide a promising solution to these problems and have been previously used to selectively concentrate biological particle such as bacteria. The microfluidic devices in this work were created with a 3D mircofabrication technique, which we also developed as part of this project. The core process of the technique is the etching of 3D structures in silicon with a single plasma etch utilizing an effect known as reactive ion etch lag (RIE lag). Using this unique process, 3D devices are fabricated in both silicon and the polymer polydimenthylsiloxane (PDMS). Using both numerical modeling and experimental results, we show how these 3D structures enhance the performance of the dielectrophoretic devices. The main findings indicate that 3D structures can help reduce Joule heating in the devices and lower the applied voltage necessary to operate the devices. Additionally, within this work, we develop a new dielectrophoresis technique called off-chip passivated-electrode, insulator-based dielectrophoresis microchip (O"DEP). This technique combines the sensitivity of electrode-based dielectrophoresis (eDEP) with the high-throughput and inexpensive device characteristics of insulator-based dielectrophoresis. The result is a cartridge based system which is accessible, economical, high-performance, and high-throughput technologies allowing timely detection of pathogenic bacteria.
Raman Spectroscopy of Colloidal Nanoparticles in Liquid Core Photonic Crystal Fibers (2009)

This Masters thesis examines Raman enhancements in Liquid Core Waveguides for the purpose of studying dilute solutions of Colloidal Nanoparticles.
Interfacial Electrokinetics and Electrophoresis (2001)

General membranes and porous plugs polymers and particles of biological interest inorganic particles gas/liquid and liquid/liquid interfaces - vesicles.
Identification of complex shapes using a self organizing neural system (2000)

We present a multilayer hierarchical neural system for automatic classification of complex contour patterns. The system consists of a neocognitron-like network structure combined with self-organizing maps to automatically determine feature classes. We present results showing that multilayer hierarchical networks are able to tolerate pattern distortion considerably better than standard neural network implementations.
The Management of Juvenile Chronic Arthritis (1982)

Key Words: Juvenile chronic arthritisOrthopaedic surgerySteroidsAnti-inflammatory agentsPhysical therapyOccupational therapyChild psychologyEducation
Anti-metallothionein IgG and levels of metallothionein in autistic children with GI disease (2009)

These results suggest a relationship between MT, anti-MT IgG and GI disease seen in many ASD individuals.
Digestion and Absorption of<i>Siraitia grosvenori</i>Triterpenoids in the Rat (2010)

When administered to rats, mogroside V (a pentaglucose-conjugated mogroside), the main sweetening component of Siraitia grosvenori, was mostly degraded by digestive enzymes and intestinal microflora, and was excreted in the feces as mogrol (aglycone) and its mono- and diglucosides. However, trace amounts of mogrol and its monoglucoside were found in the portal blood as sulfates and/or glucuronide conjugates.
High Performance Control (1998)

The engineering objective of high performance control using the tools of optimal control theory, robust control theory, and adaptive control theory is more achiev able now than ever before, and the ne
Screening for Traumatic Brain Injury in Troops Returning From Deployment in Afghanistan and Iraq (2007)

In this initial study, the BTBIS demonstrated promise as part of a triage process in mass casualty situations, permitting individuals with probable TBI to self-report injury and continued symptoms. Further study, including full validation and reliability assessment, is warranted and required before these screening tools can be fully evaluated.
The Influence of the Internet Surfing on the Reading Culture of Secondary School Teachers: A Case Study of Newspaper Readership in Kigumo Sub County, Kenya (2014)

Reading in the 21 st century networked society is no longer confined to the print reading. The scope of the reading has extended to the Internet sources that changed the traditional reading culture of the readers. The present study was conducted to identify the impact of the Internet surfing on the reading culture of secondary school teachers in Kigumo Sub County. The objectives of the study were to find out the influence of the internet on the reading culture of secondary school teachers in Kigumo Sub County, to determine the level of accessibility of the internet among secondary school teachers in Kigumo Sub County, to establish the level of utilization of the internet among secondary school teachers in Kigumo Sub County and to assess the preference of digital reading to print reading among secondary school teachers in Kigumo Sub County. Questionnaires that were designed purposefully to provide answers to the research questions were administered to teachers randomly selected in Kigumo Sub County. The study population comprised all the 328 teachers in the 36 secondary schools in Kigumo Sub County. A pilot test was conducted to detect weaknesses in design and instrumentation. Data analysis was done by use of descriptive statistics namely; mean mode, percentages, tables and bar graphs. Results reveal that the reading behavior of the online readers is in transition as the Internet surfing has increased non-sequential reading, interactive reading, superficial reading, and extensive reading and at the same rates is responsible for decreasing concentrated and indepth reading. Marshall McLuhan theory among others was used as the theoretical framework to explain the variables used in the research. From the findings recommendations were made that Readings should be promoted through partnership collaboration between the public and private sectors such as publishers, booksellers, librarians to encourage readership campaign, proper training of internet use should be provided to the teaching staffs to accelerate access to different electronic sources of information and support their teaching activities and that online
Adapted content delivery for different contexts (2003)

In this paper, we present a framework which allows adapted content delivery for different target contexts. This framework is based on a universal profiling schema, UPS, for describing the environment characteristics and on an profile exchange protocol. In the server and the proxy side, we give a strategy for matching the different constraints (clients, servers, content, etc.) in order to find an agreement between the server adaptation capabilities and the client preferences and constraints. Usually such environments are subject to frequent changes. To tackle this difficulty, we propose a dynamic adaptation approach based on XSLT for structural transformation and resource aware transcoders for media adaptation.
Refracted Near-Field Characterization Of Ion Exchanged Glass Waveguides And Device Simulation (1989)

The refractive index profile of single mode integrated optical strip waveguides, fabricated by a field assisted ion exchange process in glass are determined by the refracted near-field technique. Two-dimensional refractive index profiles are directly measured with a precision of Δn = 0.001 and a spatial resolution of 0.8 μm. This technique is nondestructive, and requires minimal sample preparation. Quantitative data of the index profile are obtained, which are the basis for an efficient control of ion exchange processes and a simulation of integrated optical devices. The index profile is scanned automatically yielding the two dimensional index distribution. By the effective index method the depth coordinate of the two-dimensional profile is eliminated and the effective index profile is used for BPM-simulations of devices.
Minimum Cost Trend-Free Run Orders of Fractional Factorial Designs (1988)

Run orders of fractional factorial designs which minimize a cost function based on the number of times the factors change levels during the time sequence in which the runs are performed and which simultaneously have all factor main effects components orthogonal to a polynomial time trend are found for a wide variety of factorial plans. A construction technique based on a generalized foldover scheme is presented.
Mutant Adenosine Deaminase 2 in a Polyarteritis Nodosa Vasculopathy (2014)

Recessive loss-of-function mutations of ADA2, a growth factor that is the major extracellular adenosine deaminase, can cause polyarteritis nodosa vasculopathy with highly varied clinical expression. (Funded by the Shaare Zedek Medical Center and others.).