gebhart/patrepeval huggingface dataset:
Filter coefficient interpolated timing recovery in sampled coherent PSK receivers (2003)

Timing recovery from input phase shift keying (PSK) receiver samples is considered for a Nyquist data transmission link. Adjustment of the timing phase of the input analog-to-digital (A/D) converter is not allowed, and thus timing recovery is based completely on received samples and is asynchronous with the A/D converter. To improve timing resolution over that provided by oversampling and decimation alone, the concept of filter coefficient interpolation is evaluated for a steam transmission, coherent, Nyquist-filtered, binary-PSK (BPSK) modem. This is a low-complexity, table lookup method that is useful in low-consumed-power radio modems. Performance is presented for E/sub b//N/sub 0/ down to 0 dB, and loop filtering is used to extend the threshold E/sub b//N/sub 0/ for successful receiver operation. The timing loop is shown analytically to converge in the mean-square sense. The training mode of the coherent modem, is discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Adaptive analysis of optical fringe patterns using ensemble empirical mode decomposition algorithm (2009)

An approach based on a novel technique, called ensemble empirical mode decomposition, is proposed to adaptively reduce noise and remove background intensity from a two-dimensional fringe pattern. It can solve the mode-mixing problem of the original empirical mode decomposition caused by the existence of intermittent noise in fringe signals. Then a strategy is developed to automatically identify and group the resulting intrinsic mode functions for the purpose of eliminating noise and background of the fringe pattern. This approach is applied to process the simulated and practical fringe patterns, compared with Fourier transform and wavelet methods.
Performance of CDMA multiuser detection with antenna diversity and closed loop power control (2002)

The performance of a (direct sequence spread spectrum) multiuser detection CDMA base station receiver is analyzed by simulations. In the receiver multistage multiuser detection is employed together with two antenna diversity reception and fast closed loop power control. The performance is studied in two different environments utilizing the channel models developed in the European CODIT project.
Infusions of Allogeneic Natural Killer Cells as Cancer Therapy (2014)

Natural killer (NK) cells are normal white blood cells capable of killing malignant cells without prior sensitization. Allogeneic NK cell infusions are attractive for cancer therapy because of non-cross-resistant mechanisms of action and minimal overlapping toxicities with standard cancer treatments. Although NK therapy is promising, many obstacles will need to be overcome, including insufficient cell numbers, failure of homing to tumor sites, effector dysfunction, exhaustion, and tumor cell evasion. Capitalizing on the wealth of knowledge generated by recent NK cell biology studies and the advancements in biotechnology, substantial progress has been made recently in improving therapeutic efficiency and reducing side effects. A multipronged strategy is essential, including immunogenetic-based donor selection, refined NK cell bioprocessing, and novel augmentation techniques, to improve NK function and to reduce tumor resistance. Although data from clinical trials are currently limited primarily to hematologic malignancies, broader applications to a wide spectrum of adult and pediatric cancers are under way. The unique properties of human NK cells open up a new arena of novel cell-based immunotherapy against cancers that are resistant to contemporary therapies.
Stabilization of the Nitric Oxide (NO) Prodrugs and Anticancer Leads, PABA/NO and Double JS-K, through Incorporation into PEG-Protected Nanoparticles (2009)

We report the stabilization of the nitric oxide (NO) prodrugs and anticancer lead compounds, PABA/NO (O(2)-{2,4-dinitro-5-[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2-diolate) and "Double JS-K" 1,5-bis-{1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diol-2-ato}-2,4-dinitrobenzene, through their incorporation into polymer-protected nanoparticles. The prodrugs were formulated in block copolymer-stabilized nanoparticles with sizes from 220 to 450 nm by a novel rapid precipitation process. The block copolymers, with polyethylene glycol (PEG) soluble blocks, provide a steric barrier against NO prodrug activation by glutathione. Too rapid activation and NO release has been a major barrier to effective administration of this class of compounds. The nanoparticle stabilized PABA/NO are protected from attack by glutathione as evidenced by a significant increase in time taken for 50% decomposition from 15 min (unformulated) to 5 h (formulated); in the case of Double JS-K, the 50% decomposition time was extended from 4.5 min (unformulated) to 40 min (formulated). The more hydrophobic PABA/NO produced more stable nanoparticles and correspondingly more extended release times in comparison with Double JS-K. The hydrophobic blocks of the polymer were either polystyrene or polylactide. Both blocks produced nanoparticles of approximately the same size and release kinetics. This combination of PEG-protected nanoparticles with sizes appropriate for cancer targeting by enhanced permeation and retention (EPR) and delayed release of NO may afford enhanced therapeutic benefit.
Quantum Dot Nanobarcodes: Epitaxial Assembly of Nanoparticle−Polymer Complexes in Homogeneous Solution (2008)

Multiplexed nanobarcodes have been prepared with quantum dots (QDs) and alternating amphiphilic copolymers consisting of hydrocarbons and maleic anhydride groups. In homogeneous solution, the QD-polymer complexes grow epitaxially into nanobeads of narrow size dispersity, which has been previously achieved only for micrometer-sized beads in the presence of solid supports. As a result of this new nanostructure formation mechanism, more than 250 QDs can be loaded into a nanobead of 100 nm in diameter. A model assay for sensitive detection of human prostate specific antigen has also been demonstrated using the QD-nanobeads as fluorescent reporters. This nanoparticle-polymer self-assembly technology is capable of producing a variety of nanostructures and is expected to open new opportunities in nanoparticle-based ultrasensitive detection and imaging.
Estimation of Tau and Phosphorylated Tau181 in Serum of Alzheimer’s Disease and Mild Cognitive Impairment Patients (2016)

The elevated level of cerebrospinal fluid (CSF) Tau and phosphorylated Tau181 (p-Tau181) proteins are well established hallmarks of Alzheimer's disease (AD). Elevated level of p-Tau181 can differentiate AD from other neurodegenerative disease. However, the expression level of these proteins in serum of AD patient is not well set up. This study sought to evaluate the level of Tau and p-Tau181 in serum of AD, and mild cognitive impairment (MCI) patients for an alternative approach to establish protein-based markers by convenient way. Blood samples were collected from 39 AD patients, 37 MCI patients and 37 elderly individuals as controls. The levels of Tau and p-Tau181 in the serum of the different groups were measured by label free real time Surface Plasmon Resonance technology by using specific antibodies, and were further confirmed by the conventional western blot method. An appropriate statistical analysis, including Receiver Operating Characteristic (ROC), was performed. The concentrations of serum Tau and p-Tau181 were significantly higher (p<0.00001) in AD (Tau; 47.49±9.00ng/μL, p-Tau181; 0.161±0.04 ng/μL) compared to MCI (Tau; 39.26±7.78 ng/μL, p-Tau181; 0.135±0.02 ng/μL) and were further higher compared to elderly controls (Tau; 34.92±6.58 ng/μL, p-Tau181; 0.122±0.01 ng/ μL). A significant (p<0.0001) downhill correlation was found between Tau as well as p-Tau181 levels with HMSE and MoCA score. This study for the first time reports the concentration of Tau and p-Tau181 in serum of AD and MCI patients. The cutoff values of Tau and p-Tau181 of AD and MCI patients with sensitivity and specificity reveal that serum level of these proteins can be used as a predictive marker for AD and MCI.
Securing pseudo identities in an anonymous peer-to-peer file-sharing network (2007)

MUTE is an anonymous peer-to-peer network that is used by hundreds of thousands of people to share files. Peers in this network are identified by randomly chosen pseudo identities and a probabilistic time-to-live counter is used to stop an attacker from being able to tell how far a search has come or has to go. The aim of the system is to hide the IP addresses of the file-sharers from an attacker that is acting as one or more peers inside the network. This paper describes the MUTE system, and then goes on to outline an attack on the anonymity of a peer based on “stealing” pseudo identities. We then show how using an authentication key as a pseudo identity can stop this attack and we describe the implementation of this solution as part of the MUTE system.
A novel color interpolation framework in modified YCbCr domain for digital cameras (2004)

Most digital cameras use single-CCD with color filter array to capture sub-sampled digital color images and need color interpolation to generate full resolution color details. While most color interpolation algorithms are performed in the RGB domain, we propose a new framework to perform the color interpolation in the YCbCr domain. Simulation results suggest that the proposed framework can produce significantly better quality color images compared with existing algorithms.
Synthesis of Indole Rings Fused Quinacridones. (1992)

赤色系高級有機顔料であるキナクリドソの増環型誘導体として2個のインドール環を縮合したキナクリドン(5,15-ジアルキル-5,8,15,18-テトラヒドロインドロ[3,2-a]イソドロ[3',2':5,6]キノ[3,2-i]アクリジン40,20-ジオン[6]を合成した。その際閉環位置により3種の異性体が考えられるが,400MHz1H-NMRにより非線形構造の[6]と確認した。イソドール環の縮環により,DMF中の可視スペクトルが40nm程度無置換キナクリドンより長波長シフトした。またキナクリドソ部位のN-アルキル化も行い,5,8,15,18-テトラアルキル-5,8,15,18-テトラヒドロインドロ[3,2-a]インドロ[3'2':5,6]キノ[3,2-i]アクリジソ-10,20-ジオン[7]を鮮明な赤紫色微針状晶として得た。
Biomedical Named Entity Recognition: A Survey of Machine-Learning Tools (2012)

It is well known that the rapid growth and dissemination of the Internet has resulted in huge amounts of information generated and shared, available in the form of textual data, images, videos or sounds. This overwhelming surge of data is also true for specific areas such as biomedicine, where the number of published documents, such as articles, books and technical reports, is increasing exponentially. For instance, the MEDLINE literature database contains over 20 million references to journal papers, covering a wide range of biomedical fields. In order to organize and manage these data, several manual curation efforts have been set up to identify, in texts, information regarding entities (e.g. genes and proteins) and their relations (e.g. protein-protein interactions). The extracted information is stored in structured knowledge resources, such as Swiss-Prot [1] and GenBank [2]. However, the ef‐ fort required to continually update these databases makes this a very demanding and ex‐ pensive task, naturally leading to increasing interest in the application of Text Mining (TM) systems to help perform those tasks.
Synthesis and solvent extraction studies of novel calixarene-based uranophiles bearing hydroxamic groups (1991)

Calix[n]arene-based uranophiles bearing hydroxamic groups on the lower rim (2n; n= 4 and 6) have been synthesized and the extractability (Ex%) and the selectivity towards uranyl ion (UO22+) estimated in a two-phase (water–chloroform) solvent-extraction system. Ex% for 24 and 26 increases from pH 2 and saturation is reached at around pH 5 where 100% extractability occurs. Since the pKa values for hydroxamic acids are 8–9, the apparent pKa shift caused by the UO22+-complexation amounts to 6–7 pK units. Extraction of UO22+ from aqueous carbonate solution established that 26 in the organic phase can compete efficiently with CO32– ions in the aqueous phase for UO22+ whereas in 24 and a calix[6]arene-based uranophile bearing six carboxy groups (16) UO22+ is re-extracted to the aqueous phase. The difference indicates that 26, which has the hexacoordination geometry preorganized for the binding of UO22+, is superior to 24 as a uranophile. We also found that the selectivity of 26 is superior to 16: the Ex% values for 26 is scarcely affected by the addition of competing metal cations (except Fe3+). These results show that 26 serves as an excellent UO22+-selective extraction reagent.
A Convenient Synthesis of (R)-(+)-Perillaldehyde (1988)

Abstract A short and efficient synthesis of the commercially unavailable (R)-(+) isomer of perillaldehyde from (+)-limonene oxide has been developed.
Effects of Bacillus amyloliquefaciens FZB42 on Lettuce Growth and Health under Pathogen Pressure and Its Impact on the Rhizosphere Bacterial Community (2013)

The soil-borne pathogen Rhizoctonia solani is responsible for crop losses on a wide range of important crops worldwide. The lack of effective control strategies and the increasing demand for organically grown food has stimulated research on biological control. The aim of the present study was to evaluate the rhizosphere competence of the commercially available inoculant Bacillus amyloliquefaciens FZB42 on lettuce growth and health together with its impact on the indigenous rhizosphere bacterial community in field and pot experiments. Results of both experiments demonstrated that FZB42 is able to effectively colonize the rhizosphere (7.45 to 6.61 Log 10 CFU g(-1) root dry mass) within the growth period of lettuce in the field. The disease severity (DS) of bottom rot on lettuce was significantly reduced from severe symptoms with DS category 5 to slight symptom expression with DS category 3 on average through treatment of young plants with FZB42 before and after planting. The 16S rRNA gene based fingerprinting method terminal restriction fragment length polymorphism (T-RFLP) showed that the treatment with FZB42 did not have a major impact on the indigenous rhizosphere bacterial community. However, the bacterial community showed a clear temporal shift. The results also indicated that the pathogen R. solani AG1-IB affects the rhizosphere microbial community after inoculation. Thus, we revealed that the inoculant FZB42 could establish itself successfully in the rhizosphere without showing any durable effect on the rhizosphere bacterial community.
VOID FRACTION MEASUREMENT IN SUBCOOLED FORCED CONVECTIVE BOILING WITH REFRIGERANT 12 (1990)

Abstract This article presents investigations and results of void fraction and pressure drop of dichlordifluormethane (CCl2 in forced convective, subcooled boiling. The data were taken at different heal fluxes in a 12- to 25-bar pressure range, the mass fluxes have been varied from 500 to 3000 kg/ m2 s with an inlet subcooling in the range from 10 to SO K. The experiments have been conducted in an annular test channel with a 0.016-m inner diameter and a 0.03-m outer diameter. The inner tube of the annulus was heated by direct current. The void fraction data were gauged with a γ -densitometer and a specially designed impedance void meter. The experimental results reveal that the void fraction is nearly constant from the onset of nucleation boiling to a subcooling of about δ T = 10 K. A method for predicting the void fraction based on the drift flux model will also be presented.
CFD simulation of pulsed MOCVD to reduce gas-phase parasitic reaction (1999)

A Computational Fluid Dynamics (CFD) code is used to determine the potential benefit of pulsed Metal-Organic Chemical Vapor Deposition (MOCVD). When AlN is grown using MOCVD over a range of pressures (30 to 270 Torr) and substrate temperatures (400°C to 900°C), gas-phase mixing of the precursor (TMA1) and ammonia hydride (NH<sub>3</sub>)leads to adduct formation. This adduct formation may produce some undesired particulate by-products and deplete the precursors at elevated pressure and temperature. In order to reduce this gas-phase parasitic reaction, the pulsed inlet condition as proposed by Bachmann et al. is utilized to effectively separate the precursor form ammonia in gas- phase. It is predicted that for high reactor pressure (270 Torr), the growth efficiency of AlN can be enhanced by a factor of 3 through the pulsed MOCVD technique while simultaneously reducing the particle formation. The improvement by pulsed MOCVD is also demonstrated for a proposed 3D (North Carolina State University) research reactor.
A double‐blind randomised comparison of risperidone and haloperidol in the treatment of behavioural and psychological symptoms in Chinese dementia patients (2001)

Low-dose haloperidol and risperidone were well tolerated and associated with reductions in the severity and frequency of behavioural symptoms in subjects with dementia. Risperidone may have a more favourable risk-benefit profile in view of its lower propensity to induce extrapyramidal symptoms.
A bilayer Ti/Ag ohmic contact for highly doped <i>n</i>-type GaN films (1996)

Ohmic contacts with low resistance are fabricated on n-type GaN films using Ti/Ag bilayer metallization. The GaN films are grown by low pressure metalorganic chemical vapor deposition (LP-MOCVD) with Si as the dopant. Ohmic characteristics are studied for films with carrier concentration range from 1.5×1017 to 1.7×1019 cm−3. The lowest value for the specific contact resistivity of 6.5×10−5 Ω cm2 is obtained without annealing. The barrier height of Ti on GaN is calculated to be 0.067 eV.
Practical guide to gastrointestinal function testing (1997)

Co-editors . Foreword . Preface . Abbreviations . 1. Anatomy of the Digestive System . 2. Swallowing Disorders . 3. Reflux Disorders . 4. Gastric and Small Intestinal Disorders . 5. Colonic and Anorectal Disorders . 6. Pediatric Gastrointestinal Problems . 7. Gastrointestinal Intubation . 8. Clinical Procedures . 9. Clinical Procedures in Children . Bibliography . Index
Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells. (1992)

Vascular smooth muscle cells proliferate and transform to foam cells in the process of atherosclerosis. In the present study, we demonstrated that platelet-derived growth factor (PDGF)-BB induced expression of proto-oncogene c-fms in vascular smooth muscle cells, which normally do not express c-fms, isolated from either human umbilical artery or rabbit aorta. No effect of the protein kinase C activator, phorbol ester, was demonstrated on mRNA expression of c-fms. In contrast, the scavenger receptor activity was induced by both PDGF-BB and phorbol ester. These results indicate that two characteristic genes of monocyte-macrophages were induced by PDGF-BB via the different pathways, and suggest that PDGF-BB plays an important role in initiating phenotypic conversion of smooth muscle cells to macrophage-like cells.
1-Thiosorbitol (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1-ThiosorbitolM. W. Farlow, Madison Hunt, C. M. Langkammerer, Wilbur A. Lazier, W. J. Peppel, and F. K. SignaigoCite this: J. Am. Chem. Soc. 1948, 70, 4, 1392–1394Publication Date (Print):April 1, 1948Publication History Published online1 May 2002Published inissue 1 April 1948https://pubs.acs.org/doi/10.1021/ja01184a030https://doi.org/10.1021/ja01184a030research-articleACS PublicationsRequest reuse permissionsArticle Views80Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Knapsack auctions (2006)

We consider a game theoretic knapsack problem that has application to auctions for selling advertisements on Internet search engines. Consider n agents each wishing to place an object in the knapsack. Each agent has a private valuation for having their object in the knapsack and each object has a publicly known size. For this setting, we consider the design of auctions in which agents have an incentive to truthfully reveal their private valuations. Following the framework of Goldberg et al. [10], we look to design an auction that obtains a constant fraction of the profit obtainable by a natural optimal pricing algorithm that knows the agents' valuations and object sizes.We give an auction that obtains a constant factor approximation in the non-trivial special case where the knapsack has unlimited capacity. We then reduce the limited capacity version of the problem to the unlimited capacity version via an approximately efficient auction (i.e., one that maximizes the social welfare). This reduction follows from generalizable principles.
Regulation of Mitochondrial Function and its Impact in Metabolic Stress (2015)

Mitochondria are key players in the maintenance of cellular homeostasis, as they generate ATP via OXPHOS. As such, disruption in mitochondrial homeostasis is closely associated with disease states, caused by subtle alterations in the function of tissues or by major defects, particularly evident in tissues with high metabolic demands. Adaptations in mitochondrial copy number or mitochondrial mass, and the induction of genes implicated in OXPHOS or in intermediary metabolism as well, depend on the balanced contribution of both the nuclear and mitochondrial genomes. This forms a biogenesis program, controlled by several nuclear factors that act coordinately and in a categorized manner. Dynamic changes in mitochondrial regulators are associated with post-translational modifications mediated by metabolic sensors, such as SIRT1 and AMPK. Nrf2, which induces an antioxidant protective response against oxidative stress, also modulates bioenergetic function and metabolism. Additionally, the stability of mitochondrial transcripts is decreased by miRNA detected in the mitochondria, thus affecting the bioenergetic capacity of the cell. However, mitochondrial adaptation to metabolic demands is also dependent on the removal of damaged mitochondria (mitophagy) and fission/fusion events of the mitochondrial network.
Vital Business Educators Perceptions about the Usefulness of Business Education Periodicals (2008)

Problem: The business education literature isn’t accessible. Research Questions: Which business education periodicals do vital business educators perceive to be more useful? In which databases and/or indices are they found? How much literature is fugitive? What strategies might increase literature accessibility? Research Method: Delphi technique. Data Collection Procedures:A survey was distributed to 25 vital business educators. Results: The Delta Pi Epsilon Journal and the NABTE Review were rated as essential to the profession; nine periodicals were rated as very useful; and six periodicals were rated as useful. Eleven databases and indices were identified as potentially useful. Conclusions: Approximately 37% of the studied periodicals are fugitive, confirming literature inaccessibility. Recommendations: Strategies to increase the accessibility of the business education literature include libraries carefully selecting complementary databases, getting periodicals indexed, placing periodical tables of contents on the web, improving fugitive-literature retrieval skills, and developing an electronic business education database.