gebhart/patrepeval huggingface dataset:
The effects of student employment on success in college and faculty perceptions of employed students (2016)

Student employment trends have many implications to administrators, educators, counselors, as well as the employers. The major purpose of this research was to study the impact of student employment on achievement and retention of MSU College of Technology post secondary students in Great Falls. The secondary purpose was to assess the perceptions of MSU College of Technology instructors in regard to employment. Is there conflict between teachers' academic priority and the students' work priorities? The students at MSU College of Technology are changing. The typical student is over 30, female, single and working. The majority of students have responsibilities of work, family and school. The college needs to be proactive in determining and meeting the needs of this new student population. Of the students who are at risk, 16% have considered quitting, 11 % have dropped a class, and 10% are not confident in their success at college. The review of the literature indicated that employment is a determining factor in student retention and academic success. The results of the survey indicate that more than work, motivation and organization are the determining factor in student success. Respondents who worked tended to be more efficient In managing their time and setting priorities. Also, as the number of hours worked increased, GPA tended to increase also. A majority of students are working in related employment that allows them to use the skills acquired at college.
Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor (2004)

Abstract Autism is a neurodevelopmental disability characterized by deficits in verbal communications, impairments in social interactions, and repetitive behaviors. Several studies have indicated strong involvement of multigenic components in the etiology of autism. Linkage analyses and candidate gene search approaches so far have not identified any reliable susceptibility genes. We are using a proteomic approach to identify protein abnormalities due to aberrant gene expression in autopsied autism brains. In four of eight autism brains, we have found an increase in polarity (more acidic) of glyoxalase I (Glo1) by two‐dimensional gel electrophoresis. To identify the molecular change resulting in the shift of Glo1 polarity, we undertook sequencing of GLO1 gene. Direct sequencing of GLO1 gene/mRNA in these brains, has identified a single nucleotide polymorphism (SNP), C419A. The SNP causes an Ala111Glu change in the protein sequence. Population genetics of GLO1 C419A SNP studied in autism (71 samples) and normal and neurological controls (49 samples) showed significantly higher frequency for the A419 (allele frequency 0.6 in autism and 0.4 in controls, one‐tailed Fisher's test P < 0.0079). Biochemical measurements have revealed a 38% decrease in Glo1 enzyme activity in autism brains (one‐tailed t ‐test P < 0.026). Western blot analysis has also shown accumulation of advanced glycation end products (AGE's) in autism brains. These data suggest that homozygosity for A419 GLO1 resulting in Glu111 is a predisposing factor in the etiology of autism. © 2004 Wiley‐Liss, Inc.
A new simple design model for FM demodulators using soft-limiters for click noise suppression (2002)

Application of soft-limiting in FM demodulators establishes a trade-off between click noise and continuous noise. Although this is very attractive for applications where operation above threshold cannot be guaranteed, suitable design models for these systems were not developed yet. This paper presents a simple but fairly accurate design model, suitable for optimization of the soft-limiting FM demodulator to any trade-off between click noise and background noise.
Design and optimisation of power rectifiers for passive RFID systems in monolithic CMOS circuit (2005)

In this paper, we present and analyze the most fundamental constraint of RFID systems, power rectification. This issue plays an important role in development of long-range RFID systems. Rectifiers are the key components in power rectifications and efficiency of an RFID system. Therefore this paper is concentrated in investigating this major issue. To tackle this problem a novel Schottky Barrier Diode (SBD) has been proposed. The proposed SBD provides good power conversion rate and switching properties.
Specialization for applications using shared libraries (2008)

Shared libraries have been prevalently deployed in many systems and application domains in the last decade. Their ubiquity depends largely on their allowance for sharing; ie., a single copy of the library is used across multiple applications running on a single system. Unfortunately, traditional partial evaluation does not consider the sharing issue. Specifically, libraries are treated as if they are statically linked, and sharing is not preserved during the process of creating and running specialized libraries, especially across different specialized applications. In this paper, we propose a methodology for run-time specialization that aims to maximize sharing during the whole specialization process. Specifically, we advocate a stand-alone specialization of shared libraries (independent of their clients), and propose a specialization mechanism which enables sharing of run-time specialized library code both within a specialized application and across multiple specialized applications. Our proposal includes a novel static transformation that constructs a generic specialization library/component, aiming to eliminate code duplication arising at compile-time, as well as a novel run-time specialization that eliminates code duplication occurring at run-time.
1034. 1,2,3-Benzothiadiazolium salts. Part I. The structure of Jacobson's benzothiadiazolium salts (1964)

W. H. Poesche, J. Chem. Soc., 1964, 5426 DOI: 10.1039/JR9640005426
Electric Circuit Models for the Vibration Spectrum of Polyatomic Molecules (1946)

Electrical circuits are developed to determine the normal frequencies and normal modes of vibration of polyatomic molecules having arbitrary configurations. The networks for each molecule are set up without equations from physical considerations alone and may be solved by an a.c. network analyzer, by numerical methods, or by digital (punch card, etc.) calculating machines. The networks also allow the establishment of the resultant secular equations of the molecule by simple inspection. The potential function considered is either a general quadratic form of the displacements, or it may correspond to the customary ``valence-force'' system employing stretching, bending, and twisting of the valence bonds and valence angles. A companion paper contains network analyzer tests on the CO2, OCS, and ethyl alcohol molecules by the ``valence-force'' model. Both the normal frequencies and normal modes of vibration check satisfactorily with known results within the accuracy of the instruments.
Improvements in the Pretreatment of Aluminium as a Substrate for Electrodeposition (1997)

SummaryThis paper describes some of the characteristics of a new cyanide free alloy zincate process for the pretreatment of aluminium for electroplating. The alloy composition and morphology of the deposit from the new process is compared to that obtained from a cyanide containing process and another commercially available process based on the same metals. Adhesion data and comparative data on dragout are presented for these processes.Alternative nitrate and fluoride free pretreatments are also described.
Controlled-Release Misoprostol Vaginal Insert in Parous Women for Labor Induction (2006)

In Brief OBJECTIVE: To assess the ability of a controlled-release misoprostol vaginal insert to induce labor using dose reservoirs of 25, 50, 100, and 200 μg. METHODS: This double-blind, dose ranging, randomized study was carried out in parous women requiring induction of labor at term. Each woman was randomly assigned to receive a single misoprostol vaginal insert that could remain in place for up to 24 hours and was removed for onset of active labor, an adverse event, or having reached 24 hours in situ. The primary outcome measure was time from insertion of the misoprostol vaginal insert to vaginal delivery of the neonate. RESULTS: A total of 124 women participated in the study. The median time to vaginal delivery was 27.5, 19.1, 13.1, and 10.6 hours for the 25-, 50-, 100-, and 200-μg doses, respectively. The percentage of women who delivered vaginally within 12 hours was 9%, 14%, 47%, and 53% (P<.001 using the 25-μg group as the comparator) and within 24 hours was 42%, 79%, 81%, and 70% (P=.003). Uterine hyperstimulation syndrome occurred in one woman who received the 25-μg, two women who received the 100-μg, and three women who received the 200-μg dose reservoirs. CONCLUSION: Misoprostol vaginal inserts effectively induced labor in pregnant parous women at term. CLINICAL TRIAL REGISTRATION: Clinicaltrials.gov, www.clinicaltrials.gov, NCT00346840 LEVEL OF EVIDENCE: I The controlled-release misoprostol vaginal insert effectively induces labor in parous women at term.
Automated segmentation of pigmented skin lesions in multispectral imaging (2005)

The aim of this study was to develop an algorithm for the automatic segmentation of multispectral images of pigmented skin lesions. The study involved 1700 patients with 1856 cutaneous pigmented lesions, which were analysed in vivo by a novel spectrophotometric system, before excision. The system is able to acquire a set of 15 different multispectral images at equally spaced wavelengths between 483 and 951 nm. An original segmentation algorithm was developed and applied to the whole set of lesions and was able to automatically contour them all. The obtained lesion boundaries were shown to two expert clinicians, who, independently, rejected 54 of them. The 97.1% contour accuracy indicates that the developed algorithm could be a helpful and effective instrument for the automatic segmentation of skin pigmented lesions.
Machine learning in chemoinformatics and drug discovery (2018)

Chemoinformatics is an established discipline focusing on extracting, processing and extrapolating meaningful data from chemical structures. With the rapid explosion of chemical 'big' data from HTS and combinatorial synthesis, machine learning has become an indispensable tool for drug designers to mine chemical information from large compound databases to design drugs with important biological properties. To process the chemical data, we first reviewed multiple processing layers in the chemoinformatics pipeline followed by the introduction of commonly used machine learning models in drug discovery and QSAR analysis. Here, we present basic principles and recent case studies to demonstrate the utility of machine learning techniques in chemoinformatics analyses; and we discuss limitations and future directions to guide further development in this evolving field.
0.058 mm <sup>2</sup> 13 Gbit/s inductorless analogue equaliser with low‐frequency equalisation compensating 15 dB channel loss (2017)

An inductorless 13 Gbit/s analogue equaliser with an additional low‐frequency equalisation (LFEQ) to counter the low‐frequency channel losses is presented. An active feedback topology for the proposed equaliser together with negative capacitance circuit is used to extend the bandwidth to compensate a 15 dB channel loss at Nyquist. The LFEQ improves the measured data jitter of the conventional equaliser from 0.41 to 0.12 UI, for a pseudorandom binary sequence of 2 31 − 1. The proposed prototype was implemented in 65 nm CMOS, occupying active area of merely 0.058 mm 2 . It exhibits a power efficiency of 1.07 mW/Gitb/s under a supply voltage of 1.2 V and a BER < 10 −12 .
Inversion of P-wave velocity anisotropy (1977)

We examine the way in which measurements of velocity anisotropy can add to our understanding of upper mantle structure. Measurements of P-wave velocity anisotropy in a single plane contain very little direct information about the anisotropic structure. A promising technique is to fit the observed velocity variation with a mixture of an assumed anisotropic constituent and a proportion of isotropic material. Using this technique, mixtures of orthorhombic and transversely isotropic olivine are obtained, which are in excellent agreement with observed velocity variations in the Pacific.
A study of the sheath helix with a conducting core and its application to the helical antenna (1967)

A theoretical study of the sheath helix antenna with a conducting core is made via the complex solutions of an associated determinantal equation. The variation of the characteristics of operation with respect to core size and pitch angle is established. A comparison of the complex solutions for the sheath helix and tape helix indicates that a good understanding of the helical antenna can be gained from the sheath model. In particular, explaining broadside radiation in terms of complex solutions is shown to give results in agreement with previously reported empirical data. However, this comparison also points out the limitations of the sheath model in predicting the operational parameters accurately.
Interface a prototyping experiences paving the way to e-manufacturing (2005)

Pressure to increase semiconductor manufacturing productivity remains intense. Because productivity gains resulting from larger wafers, smaller device features, and 90% and greater yields are now assumed, equipment utilization and manufacturing effectiveness have become target areas for further improvement. IC makers believe that productivity can be improved significantly by additional equipment and factory data. As a result, ISMI e-manufacturing activities have focused on the acquisition of data to enable factories capable of data-driven, real-time, automated decision-making. IC makers need these types of factories to support shrinking feature sizes and to increase overall factory productivity. This article describes results from prototypes and early production versions of equipment using the new Interface A data port
The EWS/NOR1 Fusion Gene Product Gains a Novel Activity Affecting Pre-mRNA Splicing (2002)

In extraskeletal myxoid chondrosarcoma, chromosomal translocation creates a gene fusion between EWS and the orphan nuclear receptor NOR1. The resulting fusion gene product, EWS/NOR1, has been believed to lead to malignant transformation by functioning as a transcriptional activator, but an alternative mechanism may also be involved. Here, using a newly developed functional complementation screening in yeast, we found that EWS/NOR1, but not EWS or NOR1, complemented the loss of function of the small nuclear ribonucleoprotein Snu23p, an essential factor for pre-mRNA splicing in yeast. To verify the potential function of EWS/NOR1 in mammalian cells, we next showed that overexpression of EWS/NOR1 caused increased usage of the distal 5'-splice site of pre-mRNA splicing and that EWS/NOR1 interacted with the human splicing protein U1C; neither EWS nor NOR1 had the same activity or interaction as EWS/NOR1. Altogether, our findings reveal that EWS/NOR1 gains a novel activity affecting pre-mRNA splicing.
Design of an autofocus lens for VGA ¼-in. CCD and CMOS sensors (2004)

We present the design of a lens for CCD or CMOS sensors using a new generation of lenses with electrically controlled focal length. These new elements made out of liquids (a drop of oil in water) work according to the principle of electro-wetting: the spreading of a drop of water on an electrically insulating surface can be modified by creating an accumulation of charges at the base of the drop. The densities of the two liquid phases are matched in order to keep the phases in place whatever the position of the lens. This new lens can be used in small devices to achieve auto-focus camera modules. There are several ways to integrate our adaptive optic in a fixed camera module lens, classically made up of plastic lenses. We will discuss three different configurations for a VGA system with 4 mm focal length, f/3 aperture, 60° field. The optical resolution is excellent, for object distance going from 50 mm to infinity.
Dimensional stability of exterior building products (1988)

Abstract Dimensional stability problems such as warpage, bowing and other changes in shape and size may occur when exterior building products (siding, windows) are heated by the sun. This paper describes the effects of material properties such as coefficient of thermal expansion, heat distortion temperature, modulus, and heat build‐up, caused by the sun, on dimensional stability of the exterior building products.
An HIV Cure (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Determination of 5-fluorouracil in plasma by GC/MS using an internal standard. Applications to pharmacokinetics. (1979)

An analytic method, sensitive to 5 ng/ml and specific, has been set up for the determination of unchanged 5-fluorouracil in human plasma, using gas chromatography--mass spectrometry. Its applications to the pharmacokinetic study of unchanged 5-Fluorouracil in man following an intravenous bolus, 8 hours infusion and oral administration confirmed the non-linearity of the kinetic model. (The clearances obtained with an infusion--from 5 to 60 1/min--are 10 to 60 times higher than the ones observed with a bolus--from 0.5 to 1.4 1/min.) The bioavailability of the oral form seems to be about 60 per cent and the absorption appears to be very fast. A attempt to search a mathematical non-linear model of the 5-Fluorouracil kinetics, using computer simulation, is presented.
Efficient Bounded Adaptive Tessellation of Displacement Maps (2002)

Displacement mapping is a technique for applying fine geometric detail to a simpler base surface. The displacement is often specified as a scalar function which makes it relatively easy to increase visual complexity without the difficulties inherent in more general modeling techniques. We would like to use displacement mapping in real-time applications. Ideally, a graphics accelerator should create a polygonal tessellation of the displaced surface on the fly to avoid storage and host bandwidth overheads. We present an online, adaptive, crack-free tessellation scheme for real-time displacement mapping that uses only local information for each triangle to perform a view-dependent tessellation. The tessellation works in homogeneous coordinates and avoids re-transformation of displaced points, making it suitable for high-performance hardware implementation. The use of interval analysis produces meshes with good error bounds that converge quickly to the true surface.
Assembly of Na,K-ATPase alpha-subunit isoforms with Na,K-ATPase beta-subunit isoforms and H,K-ATPase beta-subunit (1994)

cDNA encoding an epitope tag was joined to cDNAs encoding the chicken Na,K-ATPase beta 1 and beta 2 and H,K-ATPase beta-subunits to allow recognition of these beta-subunits with the same monoclonal antibody during assembly assays. cDNAs encoding chicken Na,K-ATPase alpha 1, alpha 2, or alpha 3 and Na,K-ATPase beta 1 or beta 2 or H,K-ATPase beta-subunits were transiently coexpressed in mammalian cells. Subunit assembly was assayed by immune precipitation of alpha-isoforms with a monoclonal antibody to the epitope-tagged beta-subunits. Each of the chicken alpha-isoforms assembled with each of the Na,K-ATPase beta-subunits and the H,K-ATPase beta-subunit. Each of the epitope-tagged beta-subunits also assembled with a Na,K-ATPase/Ca-ATPase chimera that retained only 26 amino acids of the Na,K-ATPase alpha-subunit, demonstrating that all three beta-subunits recognize this same alpha-subunit assembly site.
Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3 (2005)

IFN regulatory factor 3 (IRF3), a constitutively expressed protein localizing largely to the cytoplasm, is a primary effector of the innate immune response. Infection can trigger the phosphorylation, dimerization, and nuclear translocation of IRF3, where the factor stimulates the expression and release of IFN. In this study, we determined that the rotavirus gene 5 product, nonstructural protein 1 (NSP1), interacts with IRF3 in the infected cell. To understand the importance of the interaction, we compared IRF3 activation by rotaviruses expressing wild-type and C-truncated forms of NSP1. The analysis showed that IRF3 underwent dimerization and nuclear translocation and stimulated IFN promoter activity in infected cells expressing truncated NSP1. In contrast, infected cells expressing wild-type NSP1 were characterized by the rapid degradation of IRF3 during the replication cycle, severe decreases in IRF3 dimerization and nuclear translocation, and lack of IFN promoter activity. The implication of these results, that wild-type NSP1 is an antagonist of the IFN-signaling pathway, was confirmed in transient expression assays, which showed that wild-type NSP1, but not the C-truncated protein, induced the degradation of IRF3 fusion proteins. Related experiments indicated that NSP1 mediates IRF3 degradation through a proteasome-dependent pathway. The critical role of NSP1 in promoting cell-to-cell spread of rotavirus was demonstrated by using gene 5-specific short interfering RNAs in plaque assays. Although several viruses have been described that subvert the innate immune response by preventing IRF3 activation, rotavirus is identified as one that accomplishes this task by inducing the degradation of IRF3.