gebhart/patrepeval huggingface dataset:
Ultrasonographic modeling of diaphragm function: A novel approach to respiratory assessment (2020)

With validation, these models intend to provide a method of estimating MIP, by way of diaphragm ultrasound measurements, thereby allowing evaluation of respiratory function in patients who may be unable to reliably participate in standard spirometric tests.
Therapeutic effect of farnesylthiosalicylic acid on adjuvant-induced arthritis through suppressed release of inflammatory cytokines (2013)

Rheumatoid arthritis (RA) is an autoimmune disease characterized by pronounced inflammation and leucocyte infiltration in affected joints. Despite significant therapeutic advances, a new targeted approach is needed. Our objective in this work was to investigate the anti-inflammatory effects of the Ras inhibitor farnesylthiosalicylic acid (FTS) on adjuvant-induced arthritis (AIA) in rats, an experimental model for RA. Following AIA induction in Lewis rats by intradermal injection of heat-killed Mycobacterium tuberculosis, rats were treated with either FTS or dexamethasone and assessed daily for paw swelling. Joints were imaged by magnetic resonance imaging and computerized tomography and analysed histologically. The anti-inflammatory effect of FTS was assessed by serum assay of multiple cytokines. After adjuvant injection rats demonstrated paw swelling, leucocyte infiltration, cytokine secretion and activation of Ras-effector pathways. Upon FTS treatment these changes reverted almost to normal. Histopathological analysis revealed that the synovial hyperplasia and leucocyte infiltration observed in the arthritic rats were alleviated by FTS. Periarticular bony erosions were averted. Efficacy of FTS treatment was also demonstrated by inhibition of CD4(+) and CD8(+) T cell proliferation and of interferon (IFN)-γ, tumour necrosis factor (TNF)-α, interleukin (IL)-6 and IL-17 release. The Ras effectors PI3K, protein kinase B (AKT), p38, and extracellular-regulated kinase (ERK) were significantly attenuated and forkhead box protein 3 (FoxP3) transcription factor, a marker of regulatory T cells, was significantly increased. Thus, FTS possesses significant anti-inflammatory and anti-arthritic properties and accordingly shows promise as a potential therapeutic agent for RA. Its effects are apparently mediated, at least in part, by a decrease in proinflammatory cytokines.
Customer behaviour and data analytics (2016)

The present evolution of the electrical sector is paying increasing attention to the customer needs. This paper deals with a number of aspects addressed in the present discussions on the characteristics of individual and aggregate consumers, referring to the shape and flexibility of the demand. Specific points addressed include the role of metering, how to obtain knowledge from load pattern disaggregation and clustering, customer-related effects of microgrids development, and active users' participation in demand response initiatives.
Study on conditioning and feature extraction algorithm of photoplethysmography signal for physiological parameters detection (2011)

Photoplethysmography(PPG) signal can reflect many physiological parameters, such as heart function, blood vessel elasticity, blood viscosity and so on. It was a novel noninvasive method with the advantage of convenience and accuracy. It was important to find efficient pre-processing and feature extraction algorithms to deal with original PPG signal, which was interfered by many other factors. Many practical methods including median filtering and FIR filtering was used. A new algorithm based on wavelet transformation was proposed for eliminating the baseline drift. Feature points extraction was another key issue. An improved differential algorithm was used to solve this problem. All of these practical algorithms provided an effective platform for physiological parameters detection.
Potential-induced copper periodic micro-/nanostructures by electrodeposition on silicon substrate (2008)

We demonstrate the fabrication of large scale nano- and micropatterned copper periodic structures on a silicon substrate without imposed templates. In the electrodeposition process, we employ a periodic variation voltage in an ultrathin layer of concentrated CuSO(4) electrolyte. The pattern can be controlled by varying the frequency of the applied potential. We suggest that the observed periodic micro-/nanostructures are caused by the lag of the migrating ion concentration profile versus the applied voltage profile near the tip of the growth.
Validation of a Microsphere-Based Immunoassay for Detection of Anti-West Nile Virus and Anti-St. Louis Encephalitis Virus Immunoglobulin M Antibodies (2007)

ABSTRACT A microsphere-based immunoassay (MIA) was previously developed that is capable of determining the presence of anti-West Nile (WN) virus or anti-St. Louis encephalitis (SLE) virus immunoglobulin M (IgM) antibodies in human serum or cerebrospinal fluid. The original data set on which the classification rules were based comprised 491 serum specimens obtained from the serum bank at the Division of Vector-Borne Infectious Diseases of the Centers for Disease Control and Prevention (DVBID). The classification rules were used to provide a result and to determine whether confirmatory testing was necessary for a given sample. A validation study was coordinated between the DVBID and five state health laboratories to determine (i) the reproducibility of the test between different laboratories, (ii) the correlation between the IgM-enzyme-linked immunosorbent assay (MAC-ELISA) and the MIA, and (iii) whether the initial nonspecific parameters could be refined to reduce the volume of confirmatory testing. Laboratorians were trained in the method, and reagents and data analysis software developed at the DVBID were shipped to each validating laboratory. Validating laboratories performed tests on approximately 200 samples obtained from their individual states, the collections of which comprised approximately equal numbers of WN virus-positive and -negative samples, as determined by MAC-ELISA. In addition, 377 samples submitted to the DVBID for arbovirus testing were analyzed using the MIA and MAC-ELISA at the DVBID only. For the specimens tested at both the state and the DVBID laboratories, a correlation of results indicated that the technology is readily transferable between laboratories. The detection of IgM antibodies to WN virus was more consistent than detection of IgM antibodies to SLE virus. Some changes were made to the analysis software that resulted in an improved accuracy of diagnosis.
Spectral analysis of antepartum heart rate variability (1989)

The present paper illustrates the basic methodological aspects of the power spectral analysis applied to fetal ECG starting from a gestational age around the 25th week of gestation until term. An abdominal ECG signal is recorded and fetal and maternal QRSs are recognised through selective digital filtering and averaging techniques. Power Spectral Density (PSD) of the discrete R-R series is then calculated through an autoregressive (AR) technique. In analogy with what happens in adult human subjects, fetuses manifest variability in correspondence to particular bands in the spectrum which are sensitive to the sympatho-vagal balance which controls many cardiovascular functions and respiration in different physiological conditions. Such a method is easily implemented on a personal computer and may be used to asses the development of the autonomic nervous system in fetuses as well as to show the physiopathological reasons which perturbate the relevant control mechanisms.
Directional coupler switch in molecular-beam epitaxy GaAs (1979)

An 8-mm-long rib waveguide directional coupler has been made from a n (1×1016 cm−3) GaAs layer grown by molecular-beam epitaxy. By reverse biasing the ’’stepped Δβ’’ Schottky electrodes with less than 30 V, more than 17 dB power isolation has been achieved at 1.06 μm for both switching states. Improvements are expected with the progress in layers morphology and doping level. This is a new step towards the feasibility of optoelectronic devices by a growth technique which is very attractive for GaAs integrated circuits.
Development of Nontoxic Heat Transport Fluids for Habitat Two-Phase Thermal Control Systems (1992)

<div class="htmlview paragraph">We have successfully used techniques found in computational chemistry to identify a series of compounds for use as nontoxic heat transfer fluids for habitat two-phase thermal control systems. Our approach allows us to screen compounds, based on their molecular structure, where no thermodynamic data exists. Once compounds that have the desired properties are identified, their properties can be measured.</div> <div class="htmlview paragraph">The key problem in developing the most efficient and versatile two-phase pumped fluid system is the selection of the appropriate working fluid. Although many fluids are good candidates in terms of their thermodynamic properties, they cannot be used inside pressurized, habitat volumes due to toxicity, flammability, and thermal stability concerns.</div> <div class="htmlview paragraph">We used our computational chemistry approach based on pattern recognition techniques to correlate a molecules thermodynamic and chemical properties with its molecular structure, we have identified several perfluorocarbons that meet the NASA design requirements.</div>
The Analysis of Parking Guidance System (2015)

As the rapid development of the domestic auto industry,the construction of parking have get high- speed increase,however the parking lot management level does not have a corresponding increase. It is calling for Hitherto unknown upgrading of the level of parking lot management,especially effectively using the parking lot to get quick stop.This paper introduces the working principles of two kinds of the current parking guidance systems by analyzing the present situation and trend of guidance system of parking. It provides a new intelligent management system to guide vehicle parking quickly and orderly in large or medium- sized parking lot and reverse searching cars.
The Radiographic Prevalence of Geniculate Ganglion Dehiscence in Normal and Congenitally Thin Temporal Bones (2006)

The presence of radiographic geniculate ganglion dehiscence is common. This finding has particular importance when the middle cranial fossa or subtemporal approach is used, as the facial nerve is more at risk especially when used to address superior canal dehiscence.
Eye-tracking for detection of driver fatigue (2002)

In this paper, we describe a system that locates and tracks the eyes of a driver. The purpose of such a system is to perform detection of driver fatigue. By mounting a small camera inside the car, we can monitor the face of the driver and look for eye-movements which indicate that the driver is no longer in condition to drive. In such a case, a warning signal should be issued. This paper describes how to find and track the eyes. We also describe a method that can determine if the eyes are open or closed. The primary criterion for the successful implementation of this system is that it must be highly nonintrusive. The system should start when the ignition is turned on without having the driver initiate the system. Nor should the driver be responsible for providing any feedback to the system. The system must also operate regardless of the texture and the color of the face. It must also be able to handle diverse conditions, such as changes in light, shadows, reflections, etc.
High Level Expression and Refolding of Mouse Interleukin 4 Synthesized in Escherichia coli (1995)

Mouse Interleukin 4 is a 20-kDa glycoprotein, synthesized by activated T lymphocytes and mast cells, which regulates the growth and/or differentiation of a broad spectrum of target cells of the immune system, including B and T lymphocytes, macrophages, and hematopoietic progenitor cells. Using an inducible recA promoter and the g10-L ribosome-binding site, recombinant non-glycosylated interleukin 4 (IL-4) was expressed as 17% of total cellular protein in Escherichia coli inclusion bodies, as a reduced, inactive 14.5-kDa polypeptide. The protein was refolded and aggregates dissociated when three disulfide bonds were reformed by slowly decreasing the concentration of guanidine hydrochloride and cysteine. The oxidized monomer was purified to homogeneity by sequential ion-exchange and size exclusion chromatography. When compared with native IL-4, E. coli-derived IL-4 displayed an identical specific activity of 4-7 x 10(7) units/mg. This recombinant IL-4 contained a three-amino-acid NH2-terminal extension, which did not affect its biological activity. Purified biologically active protein consisted of three isoforms as shown by two-dimensional gel electrophoresis, with a pI greater than 9.0. These data suggest that neither glycosylation nor the NH2 terminus of mouse IL-4 play a critical role in contributing to its in vitro biological activity.
<title>Evidential reasoning based on Dempster-Shafer theory and its application to medical image analysis</title> (1993)

In this paper, we propose the knowledge representation and evidence propagation schemes based on multivariate belief functions and present a medical image recognition system as an example to demonstrate their effectiveness in evidential reasoning. The multivariate belief functions, defined in a product space, are employed to represent domain specific knowledge such as rules or propositions. The product space and its sub-spaces (margins) are composed of a set of compatible frames. The logical relationships among these margins can be easily defined by using multivariate belief functions. Propagation of evidence is executed by extending or marginalizing the associated multivariate belief function to those margins characterized by their logical relationships. By using the blackboard-based architecture and the profound features of D-S theory, the proposed image recognition system is capable of mimicking the reasoning process of a human expert in recognizing anatomical entities efficiently in a set of correlated x-ray computed tomography, proton density weighted, and T<SUB>2</SUB>-weighted magnetic resonance images. Additionally, the proposed schemes can be also applied to other problem domains by employing the appropriate knowledge base. Several experiment results are given to illustrate the performance of the proposed system.
Compressed Sensing Based Real-Time Dynamic MRI Reconstruction (2012)

This work addresses the problem of real-time online reconstruction of dynamic magnetic resonance imaging sequences. The proposed method reconstructs the difference between the previous and the current image frames. This difference image is sparse. We recover the sparse difference image from its partial k-space scans by using a nonconvex compressed sensing algorithm. As there was no previous fast enough algorithm for real-time reconstruction, we derive a novel algorithm for this purpose. Our proposed method has been compared against state-of-the-art offline and online reconstruction methods. The accuracy of the proposed method is less than offline methods but noticeably higher than the online techniques. For real-time reconstruction we are also concerned about the reconstruction speed. Our method is capable of reconstructing 128 × 128 images at the rate of 6 frames/s, 180 × 180 images at the rate of 5 frames/s and 256 × 256 images at the rate of 2.5 frames/s.
328 Reduced defibrillation energy by vagal stimulation (2005)

ROOM 2.C Optimisation of ICD therapy -DFT how to reduce it? 325 The quick implantable cardioverter defibrillator trial (Quick-ICD) is an EPS and a DFT-testing still mandatory in patients with an indication for ICD-implantation? D. Baensch on behalf of the Quick4CD investigators
ChemInform Abstract: A Facile Synthesis of Dragmacidin B and 2,5‐Bis(6′‐bromo‐3′‐indolyl)piperazine. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Identification of novel M phase phosphoproteins by expression cloning. (1996)

Using an expression cloning technique, we isolated cDNAs for eight M phase phosphoproteins (MPPs 4-11). We then used affinity-purified antibodies to fusion proteins to characterize the intracellular localization and some biochemical properties of these proteins and two others that we identified previously (MPPs 1-2). Each antibody immunoprecipitated one or two protein species of a characteristic size ranging from 17,000 to 220,000 Da. Each MPP, when immunoprecipitated from lysates of M phase cells, was reactive with MPM2, a monoclonal antibody that recognizes a group of related M phase phosphorylation sites, including F-phosphoT-P-L-Q. This reactivity indicated that all the MPPS encoded genuine M phase phosphoproteins. When antibodies to the MPPS were used for immunofluorescence microscopy, each anti-MPP gave a characteristic pattern of localization. In interphase, several of the MPPs were nuclear proteins, whereas others were cytoplasmic or distributed throughout the cell. Three MPPS were strikingly localized to interphase structures: MPP7 to centers of DNA replication, MPP9 to the Golgi complex, and MPP10 to nucleoli. In mitosis, most of the MPPs were distributed throughout the cells. Further studies of the 10 MPPs, most of which are previously undescribed, are expected to provide new understandings of the process of cell division.
Design of a Vehicle-to-Vehicle communication system on reconfigurable hardware (2009)

Vehicle-to-vehicle communication (V2VC) promises to be a next major step towards safe and efficient road traffic. This contribution presents a V2V communication system on FPGA-basis. It provides a flexible and modular hardware framework for various software-implemented V2V applications and routing algorithms. Exploiting the benefits of reconfigurable hardware the system manages to provide hardware acceleration for security processing and data preprocessing while at the same time being adaptive to traffic situations, different environment and evolving standards and applications. We present the overall structure of the system, detail modules and communication system and present special mechanisms used to exploit FPGA benefits. Finally we give results concerning performance values and resource usage.
Sugar-Integrated Gelators of Organic Solvents (2001)

Some methyl 4,6-O-benzylidene monosaccharides can act as strong low molecular weight gelators for various organic solvents. As they are accessible in a variety of homologues, each with a unique molecular architecture, they can be used for systematic studies of gelation phenomena. Structural details of their hydrogen-bond-based fiber network in the gel phase can be resolved by small angle X-ray scattering (SAXS). Analysis of the molecular arrangement in a single crystal can be a valuable tool for the prediction of gelation ability presupposing that the elongated shape of the gel fibers arises from an anisotropic assembly of the gelator molecules into one-dimensional aggregates. It is found that some derivatives act as "supergelators", which can gelate hydrocarbon solvents with 0.03-0.05 wt%. The recent results emerging from these investigations will be outlined in this article.
Increased luminescence and improved decay kinetics in lithium and cerium co-doped yttrium aluminum garnet scintillators grown by the Czochralski method (2017)

In this study, four yttrium aluminum garnet single crystals co-doped with cerium and lithium were produced by the Czochralski method and the scintillation and defect properties were investigated. Our results demonstrated an increase in luminescence with Li co-doping as well as elimination of longer decay times. Surprisingly, although Li is monovalent, no oxidation of cerium from Ce3+ to Ce4+ was found as would be expected to maintain charge neutrality. Additionally, thermoluminescence results indicated a reduction in the trapping of charge carriers by shallow and deep traps, and room temperature photoluminescence measurements showed an improvement in the Ce3+ 5d to 4f transition efficiency.
Substitute for Benzidine in Myeloperoxidase Stains (1975)

Journal Article Substitute for Benzidine in Myeloperoxidase Stains Get access Leonard S. Kaplow, M.D. Leonard S. Kaplow, M.D. Chief, Laboratory Service Veterans Administration Hospital West Haven, Conn. 06516 and Associate Professor of Pathology and Laboratory Medicine Yale University School of Medicine New Haven, Conn. 06520 Address reprint requests to Dr. Kaplow. Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 63, Issue 3, 1 March 1975, Page 451, https://doi.org/10.1093/ajcp/63.3.451 Published: 01 March 1975 Article history Received: 03 September 1974 Accepted: 10 September 1974 Published: 01 March 1975
A location authentication scheme based on adjacent users (2014)

In recent years, LBS (Location-Based Service) have been widely used. In order to attract more users, some location service providers may unite merchants to give rewards to users who check in a place and evaluate for merchant services, and this has led to location cheating attack, where some dishonest users provide false location information to defraud the location service provider. In this paper, we proposed a location authentication scheme based on adjacent nodes. When verifying the authenticity of location provided by a user, some adjacent nodes with higher credits are selected as witnesses. The location information provided by the witnesses is compared with that presented by the user to verify whether user's location is authentic or not. Through the security analysis, we prove that this scheme can effectively prevent location cheat in LBS.
TGF‐β1 regulation in hepatocyte‐NIH3T3 co‐culture is important for the enhanced hepatocyte function in 3D microenvironment (2005)

Co-culture of hepatocytes or hepatocyte spheroids with the supporting NIH3T3 in a 3D microcapsule formed with a hybrid natural/synthetic matrix has led to enhanced hepatocyte functions. We investigated the mechanism of the functional enhancement in co-culture with respect to the contributions of soluble factors and direct cell-cell interactions. The conditioned media from the co-culture induced higher P450 cytochrome oxidase activity (indicated by EROD assay) in the microencapsulated hepatocytes than the conditioned media from the NIH3T3- or the hepatocytes-alone controls. Conditioned media from physically separated co-culture of hepatocytes-NIH3T3 by a membrane insert reduced the functional enhancement. Among the known stimulators of hepatocyte functions, TGF(beta)1 is primarily responsible for the stimulation of hepatocyte functions in this 3D co-culture since the removal of TGF(beta)1 by antibody depletion eliminated the functional enhancement and the reconstitution of TGF(beta)1 restored the functional enhancement. Activation of latent TGF(beta)1 in an extracellular environment were upregulated in co-culture with no observable increase in the TGF(beta)1 expression at transcriptional and translational levels. Our data led to an improved understanding of how co-culture enhances hepatocyte functions in vitro and pave the way for further innovations in liver tissue engineering, drug metabolism studies, and other applications that require functional hepatocytes cultured in vitro.