gebhart/patrepeval huggingface dataset:
Advanced manufacturing system for automotive components production (1997)

Presents the results of a pilot project on implementation of just‐in‐time (JIT) production for an automotive component (sleeve for synchronizing groups). Describes the old manufacturing system and outlines the related problems. Proposes, with the aim of reducing set‐up times and increasing flexibility, quality and logistic performances, a new advanced manufacturing system using JIT as an approach. Presents a summary of costs and benefits arising from the new system, outlining factors such as a total cost of $3 million and a lead time reduction of 60 days.
The vertebral body fracture in osteoporosis: restoration of height using percutaneous vertebroplasty. (2005)

Percutaneous vertebroplasty should be viewed not only as a pain-relieving procedure, but also an effective method for improving vertebral body height, kyphosis angle, and wedge angle.
Response of Rubredoxin from Pyrococcus furiosus to Environmental Changes: Implications for the Origin of Hyperthermostability (1995)

The bases of the hyperthermostability of rubredoxin from Pyrococcus furiosus (RdPf) have been probed by structural perturbations induced by solution pH and ionic strength changes. Comparison of the solution behavior at pH 7 and pH 2, as probed by far- and near-UV circular dichroism, Trp fluorescence emission, 1-anilinonaphthalene-8-sulfonate (ANS) binding, and NMR spectroscopy, reveals the presence of only minimal structural variations at room temperature. At pH 2, the protein displays a surprising nearly native-like behavior at high ionic strength while, at low ionic strength, it is capable of strongly binding the hydrophobic probe ANS. All the secondary and tertiary structural features, including the environment of the hydrophobic core, appear to be intact regardless of pH and ionic strength. The apparent "melting" or denaturation temperature at pH 2, however, is 42 degrees C lower than at pH 7. This is attributed to the perturbation of many electrostatic interactions, including the disruption of all the ion pairs, which is complete at pH 2, as indicated by electrometric pH titrations. The implications of these findings for the origins of the hyperthermostability of rubredoxin are discussed.
Aurora-A acts as a tumor suppressor and regulates self-renewal of <i>Drosophila</i> neuroblasts (2006)

The choice of self-renewal versus differentiation is a fundamental issue in stem cell and cancer biology. Neural progenitors of the Drosophila post-embryonic brain, larval neuroblasts (NBs), divide asymmetrically in a stem cell-like fashion to generate a self-renewing NB and a Ganglion Mother Cell (GMC), which divides terminally to produce two differentiating neuronal/glial daughters. Here we show that Aurora-A (AurA) acts as a tumor suppressor by suppressing NB self-renewal and promoting neuronal differentiation. In aurA loss-of-function mutants, supernumerary NBs are produced at the expense of neurons. AurA suppresses tumor formation by asymmetrically localizing atypical protein kinase C (aPKC), an NB proliferation factor. Numb, which also acts as a tumor suppressor in larval brains, is a major downstream target of AurA and aPKC. Notch activity is up-regulated in aurA and numb larval brains, and Notch signaling is necessary and sufficient to promote NB self-renewal and suppress differentiation in larval brains. Our data suggest that AurA, aPKC, Numb, and Notch function in a pathway that involved a series of negative genetic interactions. We have identified a novel mechanism for controlling the balance between self-renewal and neuronal differentiation during the asymmetric division of Drosophila larval NBs.
High-Performance Asymmetric Supercapacitor Designed with a Novel NiSe@MoSe<sub>2</sub> Nanosheet Array and Nitrogen-Doped Carbon Nanosheet (2017)

Herein, a novel asymmetric supercapacitor (ASC) with high energy density is fabricated based on the NiSe@MoSe2 nanosheet arrays and the nitrogen-doped pomelo mesocarps-based carbon nanosheet (N-PMCN) as a positive electrode and a negative electrode, respectively. The novel NiSe@MoSe2 nanosheet arrays are designed and prepared by a facile one-step hydrothermal growth method from nickel foam as a nickel precursor and nucleation framework. The N-PMCN is prepared using simultaneous CaCl2 activation and urea nitrogen-doped processes from thepomelo mesocarps as a biomass-based carbon precursor. Because of the unique nanosheet array architecture of NiSe@MoSe2 and interconnected sheet-like porous morphology with high nitrogen content (∼9 wt %) of N-PMCN, they exhibit a maximum specific capacity of 128.2 mAh g–1 and high specific capacitance of 223 F g–1 at a current density of 1 A g–1. Moreover, the assembled novel NiSe@MoSe2//N-PMCN ASC device with a maximum operating voltage of 1.65 V has demonstrated a high energy density of 32.6 Wh kg–1 at a power density of 415 W kg–1 and outstanding cycling stability with 91.4% capacitance retention after 5000 cycles in aqueous electrolyte.
Generation and Application of Monoclonal Antibody to Human Pancreatic Carcinoma (1996)

An IgG1 mouse monoclonal antibody (MAb) YPC3 against human pancreatic carcinoma was generated by a hybridoma technique. When human tissue sections were examined with immunohistochemical staining, YPC3 MAb reacted with 28 of 32 (87.5%) cases of pancreatic carcinoma tissue; it failed to react with all 11 cases of normal pancreas examined. When 99mTC-radiolabeled YPC3 MAb was administrated intravenously to the nude mice bearing xenograft of pancreatic carcinoma, clear scintigraphic visualization of tumor xenograft was found with SPECT 24 h after injection. Administration of either YPC3 MAb or LAK cells combined with YPC3 MAb could inhibit the growth of the xenografts in nude mice. These results suggest that YPC3 MAb might be an ideal carrier for radioimmunolocalization and immunotherapy of human pancreatic carcinoma.
Effects of flushing, altrenogest, and pubertal status on litter traits in gilts (1987)

We tested the effects of flushing (3.4 lb extra ground sorghum grain for at least 10 days before estrus) and estrous synchronization with altrenogest on litter traits in gilts. Altrenogest had no effect on litter size or weight, but flushing increased both traits. The response to flushing occurred entirely among gilts artificially inseminated at the pubertal estrus. Pubertal gilts represented approximately 40% of the gilts in our experiment, and their improvement in litter size was almost two pigs. When all gilts were considered, flushing improved litter size by .9 pigs.; Swine Day, Manhattan, KS, November 19, 1987
A holistic approach to mobile robot navigation using omnidirectional vision (2002)

This dissertation presents a novel methodology for vision-based robot navigation. One of the key observations is that navigation systems should be designed through a holistic\napproach, encompassing aspects of sensor design, choice of adequate spatial representations with associated global localisation and local control schemes.
Review Of Currently Used Inhalation Anesthetics: Part I (1998)

SIDE EFFECTS OF INHALED ANESTHETICS CARDIOVASCULAR SYSTEM Blood pressure: All volatile anesthetics with the exception of nitrous oxide produce a dose-dependent decrease in blood pressure. Nitrous oxide produces either no change or only a slight increase in blood pressure. The decrease in blood pressure produced by halothane and enflurane results mainly from negative inotropy (decrease in myocardial contractility), whereas hypotension produced by desflurane, isoflurane, and sevoflurane mainly result from a decrease in systemic vascular resistance. Heart rate: Isoflurane and desflurane produce a dosedependent increase in heart rate. This increase occurs at low doses of isoflurane or high doses of desflurane. It might be blunted by simultaneous use of opioids during balanced anesthesia. Nitrous oxide, halothane and sevoflurane are not associated with substantial changes in heart rate. Cardiac performance: As mentioned earlier, halothane and enflurane produce a dose dependent decrease in cardiac output due to decrease in myocardial contractility. Administration of nitrous oxide can modestly increase cardiac output because its sympathomimetic effect. High doses may cause myocardial depression. Isoflurane, desflurane and sevoflurane do not significantly alter cardiac output. Systemic vascular resistance: Isoflurane, desflurane, and sevoflurane produce dose dependent decreases in systemic vascular resistance. Pulmonary vascular resistance: Nitrous oxide is known to increase pulmonary vascular resistance, especially in patients with pre-existing pulmonary hypertension. All other inhalation agents may decrease pulmonary vascular resistance and blunt the Hypoxic Pulmonary Vasoconstriction Reflex (HPV). Coronary blood flow: Isoflurane is known to be a potent coronary artery vasodilator. Isoflurane induced coronary artery vasodilatation can lead to redistribution of coronary blood flow away from diseased areas to areas with normal responsive coronary arteries. This phenomenon is called the coronary steal syndrome. However, most clinical studies failed to prove a higher incident of myocardial ischemia due to isoflurane. Enflurane, halothane, desflurane, and sevoflurane are all weaker coronary artery vasodilator than isoflurane. Cardiac dysrhythmias: Especially halothane is known for its dysrhythmic effect in combination with catecholamines such as epinephrine. All cardiac depressant effects of volatile anesthetics are able to recover. Cardiac output, heart rate, and systemic vascular resistance usually return to base value if these agents are administered for five hours or longer.
An Instrument for Rapid Powder Flow Measurement and Temporal Fractal Analysis (1999)

An instrument enabling the measurement, at a high sampling rate, of the mass of a powder flowing from a vibrating spatula has been constructed. Semiconductor strain gauges were used in the instrument as sensitive and rapid-response transducers facilitating mass measurement in these studies. Data collection and processing was performed automatically by computer. Computer software was developed for analysis of fractal dimension as a component of the instrument, to automate an established method for determination of the temporal fractal dimension of mass flow data. The rise time response of the instrument was an order of magnitude faster than instrumentation used previously [1]. Fractal dimensions determined using this instrument in a study of lactose powders on a vibrating spatula were approximately an order of magnitude larger than those reported previously.
Learning and Detecting Activities from Movement Trajectories Using the Hierarchical Hidden Markov Models (2005)

Directly modeling the inherent hierarchy and shared structures of human behaviors, we present an application of the hierarchical hidden Markov model (HHMM) for the problem of activity recognition. We argue that to robustly model and recognize complex human activities, it is crucial to exploit both the natural hierarchical decomposition and shared semantics embedded in the movement trajectories. To this end, we propose the use of the HHMM, a rich stochastic model that has been recently extended to handle shared structures, for representing and recognizing a set of complex indoor activities. Furthermore, in the need of real-time recognition, we propose a Rao-Blackwellised particle filter (RBPF) that efficiently computes the filtering distribution at a constant time complexity for each new observation arrival. The main contributions of this paper lie in the application of the shared-structure HHMM, the estimation of the model's parameters at all levels simultaneously, and a construction of an RBPF approximate inference scheme. The experimental results in a real-world environment have confirmed our belief that directly modeling shared structures not only reduces computational cost, but also improves recognition accuracy when compared with the tree HHMM and the flat HMM.
The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection (1998)

Appropriate empirical antibiotic treatment was associated with a significant reduction in fatality in patients with bloodstream infection.
Quantitative Glycomics from Fluidic Glycan Microarrays (2009)

A hallmark of cell-surface processes involving glycans is their multivalent interaction with glycan binding proteins (GBPs). Such a multivalent interaction depends critically on the mobility and density of signaling molecules on the membrane surface. While glycan microarrays have been used in exploring multivalent interactions, the lack of mobility and the difficulty in controlling surface density both limit their quantitative applications. Here we apply a fluidic glycan microarray, with glycan density varying for orders of magnitude, to profile cell surface interaction using a model system, the adhesion of Escherichia coli to mannose. We show the quantitative determination of monovalent and multivalent adhesion channels; the latter can be inhibited by nanopartices presenting a high density of mannosyl groups. These results reveal a new E. coli adhesion mechanism: the switching in the FimH adhesion protein avidity from monovalent to multivalent as the density of mobile mannosyl groups increases; such avidity switching enhances binding affinity and triggers multiple fimbriae anchoring. Affinity enhancement toward FimH has only been observed before for oligo-mannose due to the turn on of secondary interactions outside the mannose binding pocket. We suggest that the new mechanism revealed by the fluidic microarray is of general significance to cell surface interactions: the dynamic clustering of simple sugar groups (homogeneous or heterogeneous) on the fluidic membrane surface may simulate the functions of complex glycan molecules.
Orthogonalized noise subtraction (1991)

Experience gained processing data recorded in a seismic experiment with a drilling-bit source suggests that the acquisition could be improved by integrating it with a monitoring of the principal sources of the noise due to engines and yard activity.
Frequency Compression of 7.6 kHz Speech Into 3.3 kHz Bandwidth (1983)

Telephone channels restrict the bandwidth of speech signals to approximately 0.3-3.3 kHz, with the consequence that the intelligibility of unvoiced sounds may be significantly impaired. To prevent this band limitation of unvoiced sounds while still confining the speech to the telephonic bandwidth, we propose a scheme which, on recognizing the presence of unvoiced sounds extending to 7.6 kHz, frequency maps them into the band 0.3-3.3 kHz. Four mapping laws are considered and the unvoiced speech is compressed using each law. Frequency demapping is employed, and the law that has the best spectral match to the speech spectrum is selected. Voiced speech is band limited from 0.3 to 3.3 kHz. Results measured over 16 ms, a phoneme, and word durations indicate that the adaptive frequency mapping algorithm significantly enhances the recovered speech compared to telephonic speech. Informal listening experiences support these findings.
The prophylactic effect of a dry-cow antibiotic against<i>Streptococcus uberis</i> (1995)

The prophylactic use of a dry-cow antibiotic for reducing the incidence of mastitis due to Streptococcus uberis was studied in four seasonally calving dairy herds involving 378 cows. The treatment was a long-acting dry-cow antibiotic preparation administered immediately after the last milking of lactation. New intramammary infections were identified by comparing the bacteriological status of quarters at drying off with that after calving, or through manual udder palpation during the dry period. The administration of dry-cow antibiotic to uninfected quarters at drying off reduced the overall incidence of new infections with Streptococcus uberis from 12.3% for untreated quarters to 1.2% of quarters (p<0.01). The reduction was significant (p<0.01) for both dry-period and post-calving infections. The susceptibility of uninfected quarters to new infection by Streptococcus uberis appeared to be unrelated to the infection status of a cow at drying off. Clinical infections during the dry period were most prevalent (97%) in quarters identified as having open teat canals. Fewer open teat canals (p<0.05) were observed among antibiotic treated quarters over the first 4 weeks of the dry period. Treated quarters had a lower (p<0.05) incidence of new clinical infection during the ensuing lactation and lower somatic cell counts. This did not affect production levels of milk, milk fat or protein. The results clearly indicated a prophylactic benefit for the dry cow antibiotic treatment against new Streptococcus uberis infections during the dry period.
Research of speed routing software based on Linux (2013)

Welcome to the WIT Press eLibrary - the home of the Transactions of the Wessex Institute collection, providing on-line access to papers presented at the Institute's prestigious international conferences and from its State-of-the-Art in Science & Engineering publications.
Predicting and Assessing Visual Performance with Multizone Bifocal Contact Lenses (2003)

Bifocal contact lens designs, when combined with the aberrations of the eye, will not always provide bifocal vision. Visual quality with a bifocal contact lens can be predicted based on a patient's ocular aberrations.
Campylobacter-like organisms on the human gastric mucosa. Relation to type and extent of gastritis in different clinical groups. (1987)

Three hundred and thirty-four pyloric type and 244 fundic type gastric mucosal specimens from 135 patients undergoing upper gastrointestinal endoscopy were checked for Campylobacter-like organisms (CLO) by the Warthin-Starry method. CLOs were found in 77/135 (57 p. 100) patients and in 235/578 (41 p. 100) biopsy specimens. There was no significant difference in the prevalence of CLO-positive specimens in the two types of gastric mucosa. The prevalence of CLO-positive specimens was higher in patients with duodenal ulcer than in the other patients (p less than 0.01). In the whole group, 42 p. 100 of the specimens with gastritis showed CLOs. Neither the type nor the activity of gastritis seemed to be relevant. Twenty-two per cent of the pyloric type and 36 p. 100 of the fundic type specimens classed as normal were positive for CLOs. In the normal fundic type mucosa, CLO-positive specimens were more frequent (p less than 0.01) in those patients with CLO-positive specimens from the antral area than in those without CLOs in the antrum. In 41 patients with multiple specimens from either the duodenal bulb and the stomach, chronic non specific duodenitis appeared to be more frequent in patients with CLO-positive antral specimens. The present study provided data on the frequency of gastric CLOs in a mediterranean population and confirmed that an association between CLOs and antral gastritis exists in patients with duodenal ulceration. However, data of the present investigation indicate that no relation between CLOs and the type and activity of gastritis exists and that CLOs are frequently found in the histologically normal mucosa, particularly in the body-gland area.
Surfactant-free synthesis of Cu2O hollow spheres and their wavelength-dependent visible photocatalytic activities using LED lamps as cold light sources (2014)

A facile synthesis route of cuprous oxide (Cu2O) hollow spheres under different temperatures without the aid of a surfactant was introduced. Morphology and structure varied as functions of reaction temperature and duration. A bubble template-mediated formation mechanism was proposed, which explained the reason of morphology changing with reaction temperature. The obtained Cu2O hollow spheres were active photocatalyst for the degradation of methyl orange under visible light. A self-designed equipment of light emitting diode (LED) cold light sources with the wavelength of 450, 550, and 700 nm, respectively, was used for the first time in the photocatalysis experiment with no extra heat introduced. The most suitable wavelength for Cu2O to photocatalytic degradation is 550 nm, because the light energy (2.25 eV) is closest to the band gap of Cu2O (2.17 eV). These surfactant-free synthesized Cu2O hollow spheres would be highly attractive for practical applications in water pollutant removal and environmental remediation.
Prenyl modification of guanine nucleotide regulatory protein gamma 2 subunits is not required for interaction with the transducin alpha subunit or rhodopsin. (1993)

Guanine nucleotide-binding regulatory protein (G protein) beta gamma dimers that were active in reconstitution assays were produced in insect cells using the baculovirus/Sf9 insect cell expression system. Sf9 cells were infected either singly or in combination with recombinant baculoviruses containing a human G-protein beta 1 gene or a bovine G-protein gamma 2 gene. It was possible to express the beta 1 and gamma 2 gene products independently of each other in this system, as determined by using immunological and metabolic labeling techniques. Further, the ability of recombinant beta and/or gamma chains to function in defined biochemical assays of beta gamma activity was assessed for membrane extracts and supernatant fractions from infected Sf9 cells. Extracts of cells expressing beta or gamma chain alone were inactive in these assays, whereas those from cells coinfected with beta 1 and gamma 2 did display activity. These assays were used to identify recombinant beta gamma dimer migration during chromatographic purification, and the recombinant dimers were purified to near homogeneity. Both the membrane-associated and soluble beta gamma dimers facilitated rhodopsin-catalyzed guanosine 5'-[gamma-thio]triphosphate binding to Gt alpha, the GTP-binding subunit of the retinal G protein transducin (K0.5 of 13 +/- 2 and 36 +/- 5 nM, respectively). Both recombinant beta gamma dimers also facilitated the pertussis toxin-catalyzed ADP-ribosylation of Gt alpha with equal potency (K0.5 of 9 +/- 1 and 10 +/- 3 nM for membrane and soluble dimers, respectively). [3H]Mevalonolactone labeling showed that the gamma 2 subunits of membrane-associated beta gamma dimers incorporated radiolabel, whereas in the soluble form they did not. Thus, prenyl modification of gamma 2 directs the membrane association of the beta 1 gamma 2 dimer and increases its apparent affinity for receptor, but it is not required for the functional interaction(s) of the dimer.
An adaptive generalized sidelobe canceller with derivative constraints (1986)

An adaptive broad-band beamforming structure is presented which employs a gradient-based weight adjustment algorithm to minimize output variance subject to a set of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">J</tex> linear constraints on broadband directional derivatives in the desired look direction. A generalized sidelobe-cancelling structure is employed in which a nonadaptive (conventional) beamformer operates in parallel with an adaptive beamformer. The conventional portion has a broad-band beampattern which adheres to the specified constraints while the adaptive path is a cascade of a fixed signal blocking matrix and a set of tapped-delay line filters. Blocking is employed to ensure that all incident waveforms which meet the specified constraints do not reach the tapped-delay lines. As a result, an unconstrained least mean square (LMS) power minimization algorithm is employed to adapt the delay line weights. It is shown that with the addition of the directional derivative constraints, the beamformer quiescent bcampattern becomes a function of the location of the phase center used to specify the constraints. A design criterion for choosing this location is suggested and simulation experiments which illustrate the performance of this new adaptive beamformer are presented.