gebhart/patrepeval huggingface dataset:
Effect of 20-HETE Inhibition on Infarct Volume and Cerebral Blood Flow after Transient Middle Cerebral Artery Occlusion (2008)

This study examined the effects of an inhibitor of 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis, N-(3-chloro-4-morpholin-4-yl)phenyl-N'-hydroxyimido formamide (TS-011), on infarct volume, volume at risk, cerebral blood flow (CBF), and levels of cytochrome P450 (CYP450) eicosanoids in the brain after transient occlusion of the middle cerebral artery (t-MCAO) in rats. TS-011 (0.1 mg/kg, iv) reduced cortical infarct volume by approximately 70% and total infarct volume by 55%. TS-011 had no effect on the volume at risk or CBF during or up to 30 mins after the ischemic period. TS-011 reduced the delayed fall in CBF seen 2 h after reperfusion. The levels of CYP450 eicosanoids were similar in the ischemic and contralateral hemispheres after t-MCAO. TS-011 reduced 20-HETE levels in cerebral tissue by 80% but had no effect on the levels of EETs. Administration of another 20-HETE inhibitor, HET0016 (0.01 to 1.0 mg/kg, iv) or a 20-HETE antagonist 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid (10 mg/kg, iv) also reduced infarct size. These results indicate that inhibitors of the synthesis or vasoconstrictor effects of 20-HETE reduce infarct size in rats after cerebral ischemia. The effects of TS-011 are not associated with changes in the area at risk or CBF and may be because of a potential protective effect in neurons subjected to ischemic stress.
Coupling of photon energy via a multiwalled carbon nanotube array (2005)

Fluorescent beads were excited by a laser beam coupled through a multiwalled carbon nanotube array. The images of the fluorescent beads showed a distinctive dependence on the polarization direction of the laser beam owing to the surface plasmons induced from the metallic property of the array. The thickness of the array is 2μm as compared to the metallic films of tens of nanometers in thickness that are conventionally used for surface plasmon excitation. This remarkable photon coupling capacity of a multiwalled carbon nanotube array is attributed to the confinement of electrons in its outermost tube shells and ballistic transport.
Discotic liquid crystals of transition metal complexes, Part 30: spontaneous uniform homeotropic alignment of octakis(dialkoxyphenoxy)phthalocyaninatocopper(ii) complexes (2001)

Six novel octakis(dialkoxyphenoxy)phthalocyaninatocopper(II) complexes (abbreviated as [(CnO)2PhO]8PcCu (n = 9–14)) have been synthesized. It was found that these derivatives exhibit rich mesophases; Colh, Colr1, Colr2, Colr3, Coltet and Cub phases. These mesophases were characterized by microscopic observation, DSC measurements and temperature-dependent X-ray diffraction measurements. Temperature-dependent electronic spectra for the thin films of these complexes revealed that roof-top-shaped dimers in the column gradually change into cofacial dimers as the temperature is increased from rt to their clearing points. Furthermore, the phthalocyanine derivatives for n = 11–14 exhibited spontaneous uniform homeotropic alignment for the Coltet mesophase, which is the first example in discotic liquid crystalline phthalocyanine compounds.
High-Current Cockcroft-Walton Accelerator for Neutron Production (1955)

The 200-kev deuteron accelerator described utilizes a water-cooled T-Zr film as a source of 14-Mev neutrons. High voltage is provided by a Cockcroft-Walton generator of six oil-filled stages, operated at 32 kc. An rf ion source provides up to 15 ma (90 percent deuterons), at least 10 ma of which can be focused on the target. A system of forced water cooling allows at least 5 ma (at 120 kev) to be used in bombarding the target foil without reaching a surface temperature of 100°C. Observed neutron yield is approximately 2×109 neutrons/sec ma from a target containing roughly one tritium atom per four of zirconium.
In Vitro Differentiation of Bone Marrow Stromal Cells into Oligodendrocyte-like Cells Using Triiodothyronine as Inducer (2011)

An in vitro technique was devised to induced autologous adult stem cells into oligodendrocyte-like cells. In this study, a protocol was developed for the induction of bone marrow stromal cells (BMSCs) into oligodendrocyte-like cells. BMSCs were incubated in one of these three pre-inducers: dimethyl sulfoxide (DMSO), β-mercaptoethanol (βME) or biotylated hydroxyanisol (BHA), each followed by retinoic acid (RA) treatment. The percentage of viable cells in BHA-RA preinduced cells was significantly lower than the others. The results showed that the preinduced cells were immunoreactive for nestin and NF-68; among the mentioned protocols, the immunoreactivity yielded by following the DMSO-RA protocol was significantly higher than the others. Moreover, no significant immunoreactivity was observed for preinduced cells to O4, O1, MBP (myelin basic protein), S100, and GFAP (glial fibrillary acidic protein). The cells were immunoreactive to oligo-2. Two phases of induction were done: the first was a combination of basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF) and heregulin (HRG), followed by either triiodothyronine (T3) or Forskolin (FSK) as the second phase. The conclusion is that the trans-differentiation of BMSCs by DMSO followed by RA (preinduction stage) then bFGF-PDGF-HRG followed by T3 (10 ng/ml) (induction stage) can be a potential source for oligodendrocyte-like cells preparation.
El duelo: UN-a batalla. (2010)

El presente ensayo aborda el duelo desde su doble acepción: desde la connotación freudiana de trabajo frente a la pérdida de un objeto de amor; y en tanto batalla. Se señalan diferentes tiempos lógicos del duelo y las implicaciones estructurales que estos conllevan. Igualmente, se advierte el estatuto ético del duelo por el acto que la resolución de todo duelo exige vía el sacrificio que el sujeto realiza de un trozo de sí. Los cambios a nivel del fantasma, la función de los rituales funerarios, así como la relación entre castración y muerte, son otras de las temáticas desarrolladas en este texto. Palabras Clave: duelo, falta, ética, fantasma Le deuil un-e bataille Résumé Dans cet essai le deuil est abordé dès son double acception : à partir de la connotation freudienne de travail face à la perte d'un objet d'amour; et en tant que bataille. Des différents temps logiques du deuil sont signalés ainsi que les implications structurales qu’ils entraînent. De même, l’on remarque le statut éthique du deuil à travers l'acte que la résolution de tout deuil exige au moyen du sacrifice que le sujet fait d’un morceau de lui-même. Les changements qui deviennent au niveau du fantôme, la fonction des rites funéraires, ainsi que la relation entre castration et mort, seront aussi des sujets développés dans ce texte. Mots-clés: deuil, manque, éthique, fantôme The mourning, a struggle Summary The current essay deals with the mourning from its double meaning: from Freudian connotation of work facing up the loss of an object of love; and as a struggle. Several normal times of mourning and the structural implications they involved are highlighted. As well, an ethical status of the mourning is noticed, due to the determination every mourning demands through the sacrifice of a part of the subject itself. The changes concerning the ghost, the function of funeral rites, as well as the relation between castration and death are other topics to be developed in this text.Key words: mourning, lack, ethics, ghost. .
Farbabweichungen bei Black Cherry nehmen zu : Mangel an geeigneten Furnierstämmen - Farbabweichung im Kochprozess nur bedingt beeinflussbar (2007)

Der Amerikanische Kirschbaum Black Cherry (Prunus serotina Borkh.) zahlt zu den wichtigsten europaischen Importholzern fur die Mobelindustrie und den hochwertigen Innenausbau. Das Holz wird insbesondere auf Grund seiner warmgetonten rotbraunen Farbe und feinen Struktur fur hochste dekorative Anspruche auf dem nordamerikanischen und europaischen Markt geschatzt. Die hohe Nachfrage nach Black Cherry hat aber dazu gefuhrt, dass die fur die Furnierherstellung geeigneten Qualitaten in Stammform und Farbe in den naturlichen Verbreitungsgebieten (Nordosten der USA) stark zuruckgegangen sind und zunehmend Holz auf den europaischen Markt kommt, das z. T. erhebliche Farbvariationen aufweist. Die alternative holzwirtschaftliche Nutzung der einheimischen Art Prunus avium Mill. (Europaischer Trauenkirschbaum) ist auf Grund des vergleichsweise geringen mengenmasigen Aufkommen und der geringeren Stammdimensionen stark begrenzt. Bei der Be- und Verarbeitung von Black Cherry werden zunehmend ungleichmasige Farbanderungen reklamiert, die zu hohen wirtschaftlichen Verlusten in der Furnier- und Mobelindustrie fuhren. Im Rahmen eines Forschungsvorhabens wurde die Farbentstehung im lebenden Baum, die Ursachen fur die unterschiedliche Farbauspragung sowie das Farbverhalten im Produktionsprozess der Furnierherstellung grundlegend untersucht.
WAVer: A Model Checking-based Tool to Verify Web Application Design (2006)

Web Applications are becoming more and more widespread and efficient, then an increase of their reliability is now strongly required. Hence methods to support design and automatically perform validation of a Web Application (WA) could be helpful. In this paper we present WAVer, a prototype tool for performing the verification of a WA design by means of Symbolic Model Checking techniques. The tool first performs the modeling of the WA and furthermore verify it by means of a model checker. Specifically, the mathematical model of the WA is represented by a Finite State Machine (FSM). Then, by using the CTL formal language, we formalize basic criteria to establish correctness of the application. The prototype system we have implemented embeds a component which automatically imports WA design from a UML tool; CTL specifications are added and translated as source code for NuSMV model checker. Finally, the checker performs verification: if there is a violation of specifications, NuSMV allows to locate errors in WA design and appropriate adjustments are carried out.
The Yeast Two-hybrid System: Criteria for Detecting Physiologically Significant Protein-Protein Interactions (1999)

In vivo transcription-based assays for protein-protein interactions such as the two-hybrid system are powerful methods for identifying novel proteins based on their physical association with known proteins of biological interest, or for characterizing the degree and nature of interactions between sets of proteins. Because of the complexity inherent in assays taking place within a living organism, a key issue for the effective use of two-hybrid approaches is the ability to determine whether apparent interactions are likely to be physiologically relevant. In this article, a number of the different two-hybrid systems currently available for use will be reviewed. Then, taking as a model one such system, the Interaction Trap, examples of different reagents for use in varying the affinity range of detectable interactions will be outlined. Also set forth are a number of protocols to establish an appropriate set of conditions for either screening a library or analysing the interaction phenotype between protein sets. Finally, a number of general guidelines are suggested for trouble-shooting two-hybrid results, and for eliminating falsely positive interactions.
Cardiomyocyte VEGFR‐1 activation by VEGF‐B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction (2009)

Mounting evidence indicates that the function of members of the vascular endothelial growth factor (VEGF) family extends beyond blood vessel formation. Here, we show that the prolonged intramyocardial expression of VEGF-A(165) and VEGF-B(167) on adeno-associated virus-mediated gene delivery determined a marked improvement in cardiac function after myocardial infarction in rats, by promoting cardiac contractility, preserving viable cardiac tissue, and preventing remodeling of the left ventricle (LV) over time. Consistent with this functional outcome, animals treated with both factors showed diminished fibrosis and increased contractile myocardium, which were more pronounced after expression of the selective VEGF receptor-1 (VEGFR-1) ligand VEGF-B, in the absence of significant induction of angiogenesis. We found that cardiomyocytes expressed VEGFR-1, VEGFR-2, and neuropilin-1 and that, in particular, VEGFR-1 was specifically up-regulated in hypoxia and on exposure to oxidative stress. VEGF-B exerted powerful antiapoptotic effect in both cultured cardiomyocytes and after myocardial infarction in vivo. Finally, VEGFR-1 activation by VEGF-B was found to elicit a peculiar gene expression profile proper of the compensatory, hypertrophic response, consisting in activation of alphaMHC and repression of betaMHC and skeletal alpha-actin, and an increase in SERCA2a, RYR, PGC1alpha, and cardiac natriuretic peptide transcripts, both in cultured cardiomyocytes and in infarcted hearts. The finding that VEGFR-1 activation by VEGF-B prevents loss of cardiac mass and promotes maintenance of cardiac contractility over time has obvious therapeutic implications.
3-Pyrrolylsulfonium Salts and 3-Pyrrolylsulfonium Ylides (1989)

The 2-pyrrolylsulfonium salts 2 rearrange in trifluoroacetic acid into the thermodynamically more stable 3-pyrrolylsulfonium salts 5. These can be deprotonated (R1 = H) by potassium hydroxide to give the extremely hygroscopic and relatively unstable 3-sulfoniopyrrolide ylides 6.
SQL Server 2000: The Complete Reference (2000)

From the Publisher:
Master the revolutionary new release of Microsoft's high-performance,scalable database management system. This complete reference explains installation,configuration,administration,replication,security,backup,and recovery. You'll also learn to exploit all the advanced features of SQL Server 2000,including the Enterprise Manager,TSQL,data warehousing,and OLAP services. 
The ultimate resource on Microsoft's reliable database and analysis system Build and manage highly available distributed database applications using SQL Server 2000 and the comprehensive information in this volume. You'll get full details on SQL Server 2000 system and platform architecture,administration,application development,and enterprise services. Learn to program SQL Server with Transact-SQL,handle multi-dimensional data processing with the Analysis Services,use Data Transformation Services,implement data mining and data warehousing techniques,back up and restore databases,and manage security,performance,and more. Complete with real-world examples,SQL Server 2000: The Complete Reference is an invaluable tool for DBAs,operators,developers,and network administrators of all skill levels. 

Install,configure,and administer SQL Server 2000Build and deploy Web-enabled,scalable,e-commerce database solutions with XML supportUse permissions,logins,user accounts,and roles to secure databases and serversWrite and deploy T-SQL scripts,stored procedures,triggers,and queriesTake full advantage of the new English Query platform Populate,maintain,and analyze data warehouses and data martsPlan and set up replication and distributed transactions with Data Transformation Services(DTS)Build and manage OLAP cubes and systemsManage multiple,isolated installations of SQL Server from a single machineConfigure fail-over clustering and implement sound disaster recovery procedures
Photophysics of Indocarbocyanine Dyes in Organic Solvents (1998)

Abstract The absorption and fluorescence properties of a series of 18 indocarbocyanine dyes in organic solvents have been determined. The wavelengths of the absorption and fluorescence maxima, the fluorescence lifetimes and the fluorescence quantum yields relative to the benzo‐15‐crown‐5‐substituted phthalocyanine have been measured. The results are discussed in relation to the molecular structures or the dye studied.
Optimisation of weighted SAW grating reflectors with minimised time delay deviation (2002)

This paper discusses a method of designing weighted SAW grating reflectors which enables one to develop the filters having a small group delay deviation, a flat passband and steep responses in transition bands. Both electrode width and withdrawal-weightings were adopted to realise weighted reflectors. An SAW delay line employing the optimally designed reflector was fabricated, and the reflector performance was discussed. The group delay deviation of less than 80 ns in the stopband was achieved at the centre frequency of 200 MHz. For practical applications, an SAW IF filter employing the reflectors was fabricated. The reflector response is vividly reflected on filter performance, achieving the group delay deviation of less than 80 ns in the passband.
Adsorption Characteristics of an Immobilized Metal Affinity Membrane (1991)

An immobilized metal affinity (IMA) hollow-fiber membrane was prepared by radiation-induced graft polymerization of glycidyl methacrylate (GMA) onto a porous polyethylene hollow fiber, followed by chemical conversion of the produced epoxide group into an iminodiacetate (IDA) group and its chelation with copper(II) ion. The IDA hollow fiber, whose degree of GMA grafting was 120%, was found to retain 0.42 mol of Cu ion/kg of dry weight of the resulting IMA hollow fiber. The pure water flux of the affinity membrane was 0.90 m/h at a filtration pressure of 1 x 10(5) Pa. The 0.1 g/L L-histidyl-L-leucine (His-Leu) solution permeated across the IMA hollow fiber, whose inner diameter and thickness were 0.78 and 0.365 mm, respectively, at a prescribed filtration pressure ranging from 0.2 x 10(5) to 1.0 x 10(5) Pa. The adsorption of His-Leu during permeation of the solution showed that the overall adsorption rate was independent of the filtration pressure, i.e., the residence time, because of the negligible diffusional resistance of His-Leu to the pseudobioaffinity ligand located on the pore surface of the membrane. No deterioration in the adsorption capacity was observed after five cycles of His-Leu adsorption, its elution, and reimmobilization of copper. The adsorption isotherm of bovine serum albumin (BSA) on the IMA hollow fiber was measured and compared with that for the conventional agarose-based bead containing the IDA-Cu ligand.(ABSTRACT TRUNCATED AT 250 WORDS)
Intelligent back end of a goal directed simulation environment for discrete-part manufacturing (1989)

This paper discusses the issues involved in developing an intelligent back end for a goal directed simulation environment. The intelligent back end serves to analyze the simulation output and suggest changes to the model parameters that may lead the simulation towards the goals. The main thrust is on incorporating domain behavioral knowledge to the back end. A discussion on issues that need to be considered when conducting a simulation analysis of manufacturing systems is given. This is followed by a classification of manufacturing systems developed to aid in the development of the rule base. This rule base essentially emulates the thought process of a simulation analyst. Finally a sample rule base is given, followed by future research directions.
A Moving Chamber Design for Measuring Soil Respiration Rates (1974)

A system is described for measuring in situ CO2 evolution rates from forest soil. The apparatus incorporates an infrared gas analyzer with open air flow through 10 chambers which sequentially lower over the forest floor during measurements and raise after measurements are complete. Unlike methods using stationary chambers, this system allows litter and soil horizons to undergo a natural drying cycle. Litter moisture under stationary chambers was 76 % of dry weight at the end of a 3-day sample period as compared to 40 % under moving chambers and 39 % in control plots. Carbon dioxide evolution rates from plots enclosed by stationary chambers ranged from 54 to 90 % higher than those from moving chamber plots. Effects of such discrepancies in calculating the carbon balance of forest ecosystems are discussed. Application of the moving chamber apparatus in monitoring gaseous losses from biodegradable waste such as by-products of petroleum is also discussed.
A memory optimal BFGS neural network training algorithm (2003)

This paper considers the implementation of a novel memory optimal neural network training algorithm which maximises performance in relation to available memory. Mathematically, it is similar to the full memory BFGS training when there are no constraints on memory and to the variable memory (VM) BFGS when memory is limited. However, it requires less computations per iteration than VM and uses a much better strategy for discarding old curvature information when memory is limited.
ρ-ISOHUMULONES (1967)

The sodium borohydride reduction of isohumulones A and B gives four diastereoisomeric reaction products. They are called ρ-isohumulones A1, A2, B1 and B2. This paper describes their isolation, their characterization and some of their properties which are of importance in brewing.
The Aging Brain (2008)

Aging is accompanied by cognitive decline in a major segment of the population and is the primary risk factor for Alzheimer's disease and other prevalent neurodegenerative disorders. Despite this central role in disease pathogenesis and morbidity, the aging of the brain has not been well understood at a molecular level. This review seeks to integrate what is known about age-related cognitive and neuroanatomical changes with recent advances in understanding basic molecular mechanisms that underlie aging. An important issue is how normal brain aging transitions to pathological aging, giving rise to neurodegenerative disorders. Toxic protein aggregates have been identified as potential contributory factors, including amyloid beta-protein in Alzheimer's disease, tau in frontotemporal dementia, and alpha-synuclein in Parkinson's disease. However, current models of pathogenesis do not explain the origin of the common sporadic forms of these diseases or address the critical nexus between aging and disease. This review discusses potential approaches to unifying the systems biology of the aging brain with the pathogenesis of neurodegeneration.
지니계수로 추정한 대학입학수학능력시험 성적의 하향평준화 분석 - ‘이해찬 1세대’를 중심으로 (2007)

본 연구는 2002년도 평준화 확대정책이후 학생들의 수능성적이 하향평준화 되었는지를 밝히기 위해서 시도되었다. 본 연구에서 사용된 대학입학수학능력시험 성적자료는 한국교육과정평가원에서 발표한 보도 자료와 시중 입시학원 홈페이지에 게재된 자료(중도 절단된 자료)이다. 이들 자료들이 서로 동일함을 검증하고, 시중 입시학원...
Angiotensin Convertase Activities in Human Alveolar Macrophages: Effects of Cigarette Smoking and Sarcoidosis (1979)

Angiotensin I convertase activity has been found in human alveolar macrophages from normal volunteers and patients with pulmonary sarcoidosis. This activity is higher in the alveolar macrophages from smokers than from nonsmokers, and is even more elevated in sarcoid patients. The activity can be detected with both angiotensin I and bradykinin analogs and appears to require protein synthesis, but the enzyme is not secreted by alveolar macrophages in culture.
Target recognition based on convolutional neural network (2017)

One of the important part of object target recognition is the feature extraction, which can be classified into feature extraction and automatic feature extraction. The traditional neural network is one of the automatic feature extraction methods, while it causes high possibility of over-fitting due to the global connection. The deep learning algorithm used in this paper is a hierarchical automatic feature extraction method, trained with the layer-by-layer convolutional neural network (CNN), which can extract the features from lower layers to higher layers. The features are more discriminative and it is beneficial to the object target recognition.