gebhart/patrepeval huggingface dataset:
Androgenic Induction of Growth and Differentiation in the Rodent Uterus Involves the Modulation of Estrogen-Regulated Genetic Pathways (2004)

The androgen receptor (AR) is expressed in the uterus; however, the role of AR in female reproductive physiology is poorly understood. Here we examined the effects of androgens on uterine growth and gene expression in adult ovariectomized rats. Nonaromatizable AR-selective agonists potently stimulate hypertrophy and induce significant myometrial expansion distinct from that induced by 17beta-estradiol (E2). In the endometrium, androgens only modestly increase epithelial cell height and antagonize the trophic effects of E2. To identify underlying mechanisms, global changes in RNA levels 24 h after stimulation with E2 and 5alpha-dihydrotestosterone (DHT) were compared. A total of 491 genes were differentially expressed after E2 treatment, including key regulators of tissue remodeling, cell signaling, metabolism, and gene expression. Of the 164 transcripts regulated by DHT, 86% were also affected by E2, including trophic genes like IGF-I and epithelial secretory genes such as uterocalin. In estrogen receptor (ER)alpha knockout mice, DHT cannot induce uterine growth, suggesting a key role for ERalpha. However, DHT appears not to activate ERalpha directly because DHT induction of IGF-I is blocked by the AR antagonist bicalutamide, and multiple genes regulated directly by ERalpha were not induced by DHT. The similarity between estrogens and androgens instead could reflect general trophic signaling in reproductive tissues because 93 of the 503 genes regulated in the uterus are similarly affected during prostate growth. Thus androgens regulate the trophic environment and architecture of the rodent uterus via a gene expression program that is overlapping but distinct from the estrogen response.
A Network Access Control Approach for QoS Support Based on the AAA Architecture (2010)

The primary role of network access control is to decide on the validity of user's identity accepted into the networks and authorization accessed to the particular resource so that users conforming to their established access polices achieve predefined services. This paper presents a specific scenario which supports quality of service (QoS) in network domain. The QoS access rules are based not only on the identity of end users but also authorization policies related to those users. To achieving that goal, it is necessary to add new functions as QoS authentication and QoS Authorization to the traditional access control schemes, and also some entities able to administrate the information relevant to QoS requirement, identity and decisions. The proposed approach is based on the 802.1X framework and the Authentication, Authorization and Accounting (AAA) architecture owing to the fact that they are the most widely accepted and deployed standards for network access control. XACML (eXtensible Access Control Markup Language) is used to express QoS resource assignment and authorization policies, and SAML (Security Assertion Markup Language) is selected to exchange and transport related messages. The proposed approach supports QoS provision by ensuring that only validated user with appropriate QoS requirement which satisfies the QoS access policies can get resource reserved, then the user can use the resource exclusively during the corresponding QoS session. This approach provides QoS support effectively cooperating with resource reservation technology.
Effect of hafnium on the castability of directionally solidified nickel-base superalloys (2002)

Abstract The effect of Hf additions on the solidification characteristics and castability of the Ni-base superalloy IN792 has been studied. A quenching technique was employed to freeze-in the microstructure during solidification. The crack length in tube-shaped demonstration castings was evaluated. Hf additions were found to reduce the hot-tearing susceptibility significantly. Hf also caused a more gradual decrease of the liquid fraction with temperature in the last stages of solidification, which was observed to improve castability in other alloys previously and which can be correlated with lower strains and strain rates in the vulnerable period where hot tears form. It was also found that the γ/γ′ rosette structure, often referred to as γ/γ′ eutectic in the literature, actually forms by a discontinuous precipitation mechanism from the solid. The amount of γ/γ′ observed in the interdendritic area, therefore, does not reflect the amount of remaining liquid in the last stages of solidification.
Automatic extraction of usable information from unstructured resumes to aid search (2010)

This paper describes a system for automated resume information extraction to support rapid resume search and management. The system is capable of extracting several important informative fields from a free format resume using a set of natural language processing (NLP) techniques. We describe a working system, for automatic resume management. The system is capable of extracting six major fields of information as defined by HR-XML. Experimental results carried out on a large number of resumes show that the proposed system can handle a large variety of resumes in different document formats with a precision of 91% and a recall of 88%.
An algorithm for detection and phase estimation of protective elements periodic lattice on document image (2017)

Various periodic security elements, such as holograms, watermarks, and guilloches, are applied to documents in order to protect against counterfeiting. These elements can be detected and used to automatically check the authenticity of a document and to identify its type. They also make it possible to use special OCR system parameters in areas of security elements. This paper is devoted to developing methods for the detection and localization of periodic background patterns based on two-dimensional discrete Fourier transform. The model of a document image with a periodic background structure is considered. Algorithms for the detection and localization of background structures that follow from the model are discussed. The behavior and accuracy characteristics of the algorithms are tested on samples of Russian passport images. Their tolerance to errors in document boundary detection are experimentally analyzed. Modified detection and localization algorithms that improve the separating detection capability and reduce localization error twofold are proposed such as masking and replacement of noisy parts of document images, background spectrum suppression, and estimation of phase components of a single periodic element.
Flash pyrolysis of 1,4-bis(5-tetrazolyl)benzene. Entry to the C8H6 energy surface (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFlash pyrolysis of 1,4-bis(5-tetrazolyl)benzene. Entry to the C8H6 energy surfaceMary W. Baum, Jose L. Font, Mindy E. Meislich, Curt Wentrup, and Maitland Jones Jr.Cite this: J. Am. Chem. Soc. 1987, 109, 8, 2534–2536Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April 1987https://pubs.acs.org/doi/10.1021/ja00242a060https://doi.org/10.1021/ja00242a060research-articleACS PublicationsRequest reuse permissionsArticle Views81Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Corrosion of Amorphous Metals (2005)

Abstract This article illustrates the three techniques for producing glassy metals, namely, liquid phase quenching, atomic or molecular deposition, and external action technique. Devitrification of an amorphous alloy can proceed by several routes, including primary crystallization, eutectoid crystallization, and polymorphous crystallization. The article demonstrates a free-energy versus composition diagram that summarizes many of the devitrification routes. It provides a historical review of the corrosion behavior of fully amorphous and partially devitrified metallic glasses. The article describes the general corrosion behavior and localized corrosion behavior of transition metal-metal binary alloys, transition metal-metalloid alloys, and amorphous simple metal-transition metal-rare earth metal alloys. It concludes with a discussion on the environmentally induced fracture of glassy alloys, including hydrogen embrittlement and stress-corrosion cracking.
Canola Quality Indian Mustard Oil (<i>Brassica juncea</i>) is More Stable to Oxidation than Conventional Canola Oil (<i>Brassica napus</i>) (2008)

Abstract Canola‐quality Indian mustard ( Brassica juncea ) is being developed as a complimentary oilseed crop to canola ( Brassica napus ) for cultivation in hot and low‐rainfall areas, where canola does not perform well. In Australia, several B. juncea breeding lines have been developed for commercial cultivation and for eventual processing as canola oil. However, there still are significant species‐based differences in the fatty acid composition with B. juncea containing lower levels of linoleic acid and higher levels of oleic and linolenic acids compared with B. napus . This has raised concern about possible oxidative stability differences between the oils. Oils (unrefined) extracted from different breeding lines of each species were subjected to accelerated autoxidation, and development of oxidative rancidity was assessed by four separate techniques: depletion of polyunsaturated fatty acids, depletion of tocopherol, development of primary oxidation products, and development of secondary oxidation products (propanal and hexanal). All the tests showed that the newly developed B. juncea oils are more stable to autoxidation than conventional canola ( B. napus ) oil, despite containing marginally higher linolenic levels. Oxidative stability does not appear to be a barrier to using oils from these emerging lines of B. juncea for partial or full replacement of conventional canola oil.
Plant Stem Cell Extract for Longevity of Skin and Hair (2008)

Stem cells of an old apple cultivar with very good storage properties were produced by applying plant cell culture technique. The extract of the cultured apple stem cells was shown to enhance the viability of umbilical cord blood stem cells, to reverse senescence signs in human fibroblast cells and to increase lifespan of isolated human hair follicles. PhytocellTech™ Malus Domestica, a cosmetic ingredient based on encapsulated extract of cultured apple stem cells, was tested in a clinical trial over 4 weeks with 20 subjects. This new ingredient was found to significantly reduce wrinkles in the crow's feet area.
FACILE SYNTHESIS OF DIALKYL FLUOROMALONATES AND THEIR DERIVATIVES (1981)

Abstract Dimethyl and diethyl fluoromalonates were prepared by the stepwise basic alcoholysis of hexafluoropropene in a total yield of 50–55%. These dialkyl fluoromalonates were alkylated with alkyl halides, and the resulting dialkyl α-fluoroalkylmalonates were cyclized with urea affording 5-fluorobarbituric acid derivatives.
Resolving classical concurrency problems using adaptive conflictless scheduling (2017)

Classical concurrency problems define environments for task processing with high contention of shared resources. The adaptive conflictless scheduling is an alternative to existing synchronization mechanisms used in known solutions of concurrency problem to provide parallel tasks processing without resource conflicts. Used in this paper scheduling concept eliminates deadlock between tasks that are caused by the wrong allocation of shared resources, regardless of the specification of task environment. The adaptive conflictless scheduling, in opposition to other solutions dedicated to specific problem, is a universal approach and can be used to solve different concurrency problems. This article presents versatility of applications of adaptive conflictless scheduling by its usage in two classical concurrency problems: readers and writers and dining philosophers. Analysis of scheduling rules, when conflictless scheduling is applied, shows lack of task starvation in both classical concurrency problems. If conflictless scheduling is used, there is no need to use any other synchronization mechanisms for control tasks access to groups of shared resources. In presented approach only the programmer has to separate tasks and for each of them has to establish and report all required shared resources. Then tasks synchronization in accessing resource groups will be performed according to the adaptive conflictless schedule, which is the sequence of conflictless schedules. The concept of conflictless scheduling bases on efficient resource conflict detection between tasks by its resource identifiers and delayed execution of conflicted tasks using many FIFO queues assigned individually to each group of shared resources. Task queues are emptied based on the conflictless schedule, which is calculated every time according to specific state of the task processing environment.
PGE, SUPPRESSES THE INDUCTION OF COLLAGEN SYNTHESIS BY CAVERNOSUM SMOOTH MUSCLE TRANSFORMING GROWTH FACTOR-/31 IN HUMAN CORPUS (1995)

Collagen synthesis has been examined in primary cultures of human corpus cavernosum smooth muscle cells (HCCSMC), the major mesenchymal cell type of the corpus cavernosum. These cultures were grown from human surgical specimens and characterized by morphological and biochemical characteristics. These cells express mRNA for transforming growth factor-p, (TGF-PI), a major regulator of extracellular matrix synthesis, as well as all three subtypes of TGF-P receptors. Human corpus cavernosum smooth muscle cells primarily synthesize types I and I11 fibrillar collagen. Treatment of HCCSMC with exogenous TGF-/3, (80 pM.) induced a 2.5- to 4.5-fold increase in the synthesis of types I and I11 collagen and resulted in detectable levels of type V/XI collagen. Treatment of HCCSMC with the eicosanoid PGE, in combination with TGF-P, suppressed the induction of collagen synthesis by TGF-P, in a dose-dependent manner, with concomitant decreases in types I, I11 and V/XI collagen. The expression of TGF-P, mRNA as well as types I and I1 TGF-/3 receptors was induced by exogenous TGF-P,. Transforming growth factor-p, mRNA induction was suppressed by PGE,. These data suggest that prostaglandins and TGF-P, may play a key role in modulation of collagen synthesis in the corpus cavernosum, and in the regulation of fibrosis of the corpus cavernosum.
DNA transformation using electrically charged tungsten microelectrodes (2002)

DNA mediated genetic transformation has opened the door to molecular engineering of numerous species. Unfortunately, many other species have so far resisted transformation often because DNA cannot be moved into their germ cells by current methods. An alternate approach was sought where DNA is electrophoresed onto the tip of a tungsten microelectrode and the electrode inserted into the cell nucleus to effect transformation. This paper shows that DNA can be electrophoresed onto the tips of tungsten microelectrodes and that tungsten microelectrodes can be used to transform the germ line cells of the nematode C. elegans.
A Pilot Study of Switch to Lopinavir/Ritonavir (LPV/r) Monotherapy from Nonnucleoside Reverse Transcriptase Inhibitor–Based Therapy (2006)

Purpose: This study evaluated the safety and efficacy of switching HIV-infected patients with stable viral suppression on nonnucleoside reverse transcriptase inhibitor/nucleoside reverse transcriptase inhibitor (NNRTI/NRTI) therapy to lopinavir/ritonavir (LPV/r) monotherapy. Method: Eligible patients discontinued NNRTI and started LPV/r. Two weeks later NRTIs were stopped and LPV/r monotherapy was continued. Patients were seen every 4 weeks throughout the 48-week study. Results: Twelve of 18 (66%) participants met the primary endpoint with HIV RNA <75 copies/mL at week 48. Thirteen (72%) participants completed 48 weeks of LPV/r monotherapy, and 12 of 13 (92%) participants on treatment at week 48 had HIV RNA <75 copies/mL. Ten (55%) of 18 patients maintained HIV RNA <75 copies/mL at all time points. Two patients were withdrawn with virologic failure but demonstrated no evidence of virologic resistance. Three (17%) patients withdrew due to diarrhea, 2 with hyperglycemia at baseline developed diabetes mellitus, 7 (54%) required addition of or increase in lipid-lowering agents, but none had grade 3 or 4 hyperlipidemia. Conclusion: Results from this pilot study suggest that LPV/r monotherapy may be an option for management of HIV infection. Larger, randomized trials are warranted to evaluate the safety, efficacy, and patient population who might benefit from LPV/r monotherapy.
Machine English Translation Evaluation System Based on BP Neural Network Algorithm (2022)

In order to solve the problems of machine translation efficiency and translation quality, this paper proposes an English translation evaluation system based on the BP neural network algorithm. This method provides users with a more intelligent machine translation service experience. With the help of the BP neural network algorithm, taking English online translation as the research object, Google's translation quality is the best, with an error frequency of only 167, while Baidu translation and iFLYTEK translation in China have a high error rate of 266 and 301, respectively, which is much higher than Google translation. A model of machine translation evaluation based on the neural network algorithm is proposed to better solve the disadvantages of traditional English machine translation. The results show that the machine translation system based on the neural network algorithm can further optimize the problems existing in machine translation, such as insufficient use of information and large scale of model parameters, and further improve the performance of neural network machine translation.
A programmable voice digitizer using the T.I. TMS-320 microcomputer (2005)

With the availability of single-chip high speed digital signal processors, it is now possible to perform computationally complex voice digitization and compression within single board constraints. A new u-processor based system has been designed, within this constraint, around the TMS-320 signal processor. The hardware blocks needed to accomplish these requirements consists of a high speed microprocessor with fast multiply/accumulate, a data management section, an analog I/O section and a host DMA interface.
Asiaticoside induction for cell‐cycle progression, proliferation and collagen synthesis in human dermal fibroblasts (2004)

Asiaticoside, isolated from Centella asiatica, promotes fibroblast proliferation and extracullar matrix synthesis in wound healing. The precise mechanism, however, in molecular and gene expression levels still remains partially understood. Using cDNA microarray technology, the alternation of genes expression profiles was determined in a human dermal fibroblast in vitro in the presence of asiaticoside (30 microg/ml). Fifty-four genes, with known functions for cell proliferation, cell-cycle progression and synthesis of the extracellular matrix, were significantly up-regulated in our "whole-genes nest" expression profile at various timepoints. Furthermore, mRNA levels and protein productions of certain genes responsible for extracellular matrix (ECM) synthesis (e.g. encoding type I and type III collagen proteins) were evaluated by Northern blot and radioimmunoassay, respectively. As a result, there is a close correlation among the gene profile, mRNA and protein production in the cells response to asiaticoside stimulation. This information could be used for exploring the target genes in response to asiaticoside in fibroblasts.
Development of protease activated interleukin-12 cytokine fusion proteins for tumor immunotherapy (TUM7P.946) (2014)

Abstract Local expression of IL-12 in the tumor microenvironment results in greatly enhanced anti-tumor responses. However, achieving local expression of cytokines at disseminated sites is challenging and systemic delivery has significant toxicity. We describe a novel approach employing an activatable fusion protein (FP) to reduce the negative side-effects of systemic delivery of the cytokine but which can preferentially affect all tumor sites. This FP consists of a cytokine linked to an inhibitory single chain antibody fragment (scFv) separated by a specific protease cleavage sequence. Importantly, the scFv does not bind to the tumor but rather binds to the cytokine keeping it inactive. However, at the tumor site, the FP can be cleaved by proteases such as Matrix metalloproteases (MMPs) that are over-expressed at tumor sites. This cleavage allows the release of the cytokine from the scFv and its binding to higher affinity receptors on immune cells. We will present data on the construction, expression, and characterization of a panel of murine and human IL-12 FPs. Using phage display, we have identified a panel of 15 scFv that bind to epitopes of murine IL-12 on either the P35 or P40 subunit as well as scFv that bind to human IL-12. Functional and biochemical data on baculovirus expressed IL-12 FPs will be presented. This strategy has the potential to reduce the negative side effects associated with systemic delivery of constitutively active cytokines yet retain their efficacy.
Randomized cooperation in asynchronous dispersive links (2009)

Recently, we proposed a decentralized cooperative communication scheme [1]. In this paper we show that randomized decentralized schemes perform well even when the cooperating nodes are asynchronous. In particular we study the attainable diversity for frequency selective channels, and the coding gain in comparison to a centralized scheme.
EPR Imaging of Metallic Lithium and its Application to Dendrite Localisation in Battery Separators (2018)

Conduction Electron Paramagnetic Resonance Imaging (CEPRI) is presented as a sensitive technique for mapping metallic lithium species. The method is demonstrated using different samples that are either thick or thin compared to the microwave skin depth. As a thin sample, microstructured metallic lithium deposits in a lithium-ion battery (LIB) separator were analysed, illustrating the capabilities of CEPRI by obtaining a high-resolution image with an image resolution in the micrometre range. Limitations and intricacies of the method due to non-linear effects caused by the skin effect are discussed based on images of surface patterns on thick metallic lithium samples. The lineshape of the EPR spectrum is introduced as a proxy to determine the suitability of CEPRI for the quantitative visualisation of metallic lithium deposits. The results suggest that CEPRI is particularly suited to analyse the spatial distribution of microstructured Li that forms during charging and discharging of LIB cells, including the localization of the point of failure in the case of an internal cell short circuit caused by dendrites.