gebhart/patrepeval huggingface dataset:
Spin-orbit coupling effect by minority interface resonance states in single-crystal magnetic tunnel junctions (2012)

Spin-orbit coupling (SOC) related to the minority interface resonance states (IRSs) of Fe(001) has been evidenced in full-epitaxial Fe(001)/MgO/Fe magnetic tunnel junctions (MTJs) from magnetotransport experiments correlated to theoretical ab initio calculations. We show that the SOC effect strongly depends on the symmetry composition of the IRS, which has been skillfully engineered via the interfacial chemical structure in the Fe(001)/MgO stack. The SOC scattering is enhanced between the majority ${\ensuremath{\Delta}}_{1}$ and minority ${\ensuremath{\Delta}}_{5}$ band near the Fermi level when presenting a ${\ensuremath{\Delta}}_{5}$ symmetry dominant IRS at the Fe/MgO interface. Our results validate the interplay between SOC and IRSs, which gives further understanding of the mechanisms responsible for the tunneling anisotropic magnetoresistance and the large perpendicular magnetic anisotropy at the Fe/MgO interface.
[Platelet aggregation: a tool for clinical investigation and pharmacological study. Methodology]. (1983)

Platelet aggregation can be measured quantitatively by continuous recording of the transmission of a beam of light across a suspension of platelets in constant agitation in an aggregometer. In routine clinical investigation, the study of platelet aggregation is performed on platelet-rich citrated plasma (PRPc). The blood sample has to be excellent to eliminate all traces of thrombin. The blood is collected in 3.8% sodium dihydrate citrate (1 volume for 9 volumes of blood). It is centrifuged at 190 g for 15 minutes at ambiant temperature. The PRPc obtained can be diluted with platelet-poor plasma (PPP) to adjust the concentration of platelets to 3 X 10(5)/microliters. The PRPc is stored at ambiant temperature in stoppered tubes under CO2 to avoid variations in pH. The maximal delay between the collection of the blood and the end of the study of aggregation is 3 hours. In certain cases, in order to define the platelet lesion and to eliminate the influence of plasma proteins, clotting factors and anti-coagulants, a suspension of washed platelets is used. The blood is collected on acid-citrate-dextrose (ACD) and centrifuged at + 37 degrees C to obtain the PRPc. The platelet deposit obtained by centrifugation of the PRPc is washed twice, according to Mustard's method, in Tyrode-albumin buffer at a concentration of 0.35% at + 37 degrees C. It is re-suspended in the same buffer solution at + 37 degrees C in the presence of apyrase and the platelet concentration is adjusted to 3 X 10(5)/microliters. The aggregation or agglutination of the platelets is induced by several agents: ADP, adrenalin, collagen, thrombin, arachidonic acid, ionophor A 23187, PAF-acether and ristocetin. The quantitative study of the aggregation curves of human platelets allows us to study the physiological and biochemical mechanisms control platelet aggregation, to recognize and classify the hereditary or acquired platelet abnormalities which lead to clinical haemorrhagic or thrombotic manifestations and to study the effect of drugs which inhibit platelet aggregation and to understand their mechanism of action.
A novel germ-line J<sub>K</sub>transcript starting immediately upstream of J<sub>K</sub>1 (1989)

Germ-line transcripts of the immunoglobulin (Ig) and T cell receptor loci are thought to be involved in the control of V gene rearrangement by rendering these loci accessible to the recombinases. We have analyzed the transcriptional activity of germ-line K alleles in two bone marrow-derived Abelson-murine leukemia virus transformed pre-B cells: 300-19, a null cell line, and P8 a mu-producing line. We found a novel germ-line JK transcript starting immediately upstream of JK1 and spliced to CK. The potential role of this transcript in the opening of the Ig K locus as well as in the ordered usage of JK segments is discussed.
Rectification Properties of Metal Semiconductor Contacts (1955)

Metal semiconductor contacts of a number of different metals were made on n- and p-type germanium using jet etching and plating techniques. Current voltage curves taken on 12 of these metals on 5 ohm-cm n-type germanium showed rectification which follows the diode equation J=J0(eqV/kT−1). No correlation was found between the reverse saturation current densities of these diodes and such properties of the metals as work function, electromotive force, etc. For those metal contacts possessing the lowest saturation current densities, calculations indicated the current crossing the contact was to a large percent hole current and that the magnitude of the hole current was controlled primarily by the geometry of the diode. All metals plated on 5 ohm-cm p-type germanium produced ohmic contacts of resistivity comparable to the spreading resistance expected for the diode geometry used. For indium diodes, a study of rectification versus resistivity indicated that the barrier produced on both n- and p-type germanium with plated contacts is one to electron flow rather than hole flow. When the assumption of only hole current crossing the barrier was made, it was shown that the I–V curves calculated from the diode theory, for different resistivities of germanium, were in qualitative agreement with the measured curves. Curves of zero voltage conductance versus temperature for different resistivities of germanium were also found to be in good agreement with those calculated on the assumption of all hole current.
Estudio clínico aleatorizado de tetracaína intranasal versus placebo en el ataque agudo de migraña en el Hospital Central Militar (2008)

Migraine is a disabling, common and chronic neurovascular disorder, that is characterized by moderate to severe headache attacks, accompanied of varied symptomatology. It has been assumed that one of the causes of the pain is the activation of the trigeminal nerve. Migraine is a well known cause of economic loss due to the decreased productivity and labor day loss. Objective: to demonstrate the effectiveness of intranasal tetracaine in treatment of acute attack of migraine and to evaluate its side effects. Material and methods: there was carried out a clinical, experimental, pilot, longitudinal, descriptive and comparative study, using intranasal tetracaine compared with placebo (isotonic saline solution 0.9 %). Thirty six patients with acute attack of migraine were included, who arrived to the emergency room and outpatient clinic of neurology. Eighteen patients were treated with tetracaine and 18 patients with placebo. Results: relief of pain was observed in 83% of patients treated with intranasal tetracaine in the first 10 minutes after the application, compared with only 6% in patients treated with placebo. This represents a statistically significant difference (p <0.0001). Only numbness throat was observed as side effect in patients treated with tetracaine.
Housing Yearbook—1942 (1942)

Housing Yearbook—1942 C. P. Straub CopyRight https://doi.org/10.2105/AJPH.32.12.1405-a Published Online: August 29, 2011
Adult Raphe-Specific Deletion of Lmx1b Leads to Central Serotonin Deficiency (2011)

The transcription factor Lmx1b is essential for the differentiation and survival of central serotonergic (5-HTergic) neurons during embryonic development. However, the role of Lmx1b in adult 5-HTergic neurons is unknown. We used an inducible Cre-LoxP system to selectively inactivate Lmx1b expression in the raphe nuclei of adult mice. Pet1-CreER(T2) mice were generated and crossed with Lmx1b(flox/flox) mice to obtain Pet1-CreER(T2); Lmx1b(flox/flox) mice (which termed as Lmx1b iCKO). After administration of tamoxifen, the level of 5-HT in the brain of Lmx1b iCKO mice was reduced to 60% of that in control mice, and the expression of tryptophan hydroxylase 2 (Tph2), serotonin transporter (Sert) and vesicular monoamine transporter 2 (Vmat2) was greatly down-regulated. On the other hand, the expression of dopamine and norepinephrine as well as aromatic L-amino acid decarboxylase (Aadc) and Pet1 was unchanged. Our results reveal that Lmx1b is required for the biosynthesis of 5-HT in adult mouse brain, and it may be involved in maintaining normal functions of central 5-HTergic neurons by regulating the expression of Tph2, Sert and Vmat2.
Beam stacking: A generalized preprocessing technique (1987)

Abstract Gaussian beams are well understood frequency- domain entities combining the directional properties of plane waves with an effectively finite region of support. These outstanding properties are retained not only on a prescribed observation plane, but throughout the propagation path. A preprocessing sequence aimed at transforming raw seismic data into beam stacks is proposed. That is, time-harmonic Gaussian beams are synthesized, replacing the plane waves generated by conventional slant-stacking procedures. The suggested scheme is characterized by an open parameter, essentially the beam width, whose selection is critical to ultimate success. Specific criteria for choosing this parameter can be given. In the limits of zero and infinite beam widths, beam stacks degenerate to the original raw data and to the conventional slant stacks, respectively. Although beam stacking is basically a frequency-domain procedure, a transformation into the time domain, using frequency constituents within selected bands, may be accomplished without losing finite spatial support. Advantages of choosing beam-stacked data as a starting point for subsequent inversion may be cited on two levels. The intrinsic property of finite spatial support overcomes edge effects. In addition, the degree of localization achieved by beam stacking may point the way to new approaches to seismic imaging.
Photophysics and photochemistry of xanthene dyes in polymer solutions and films (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotophysics and photochemistry of xanthene dyes in polymer solutions and filmsPrashant V. Kamat and Marye Anne FoxCite this: J. Phys. Chem. 1984, 88, 11, 2297–2302Publication Date (Print):May 1, 1984Publication History Published online1 May 2002Published inissue 1 May 1984https://pubs.acs.org/doi/10.1021/j150655a023https://doi.org/10.1021/j150655a023research-articleACS PublicationsRequest reuse permissionsArticle Views453Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
CloudNetSim++: A toolkit for data center simulations in OMNET++ (2014)

With the availability of low cost, on demand, and pay-as-you-go model based utility computing services offered by clouds, multiple businesses consider moving their services to the cloud. Typically, the clouds comprise of geographically distributed data centers connected through a high speed network. Most of the research and development is focused on cloud services, applications, and security issues; however, very limited effort has been devoted to address energy efficiency, scalability, and high-speed inter and intra-data center communication. We present CloudNetSim++, a modeling and simulation toolkit to facilitate simulation of distributed data center architectures, energy models, and high speed data centers' communication network. The CloudNetSim++ is designed to allow researchers to incorporate their custom protocols and, applications, to analyze under realistic data center architectures with network traffic patterns. CloudNetSim++ is the first cloud computing simulator that uses real network physical characteristics to model distributed data centers. CloudNetSim++ provides a generic framework that allows users to define SLA policy, scheduling algorithms, and modules for different components of data centers without worrying about low level details with ease and minimum effort.
Objective Clinical Regression of Metastatic Breast Cancer in Disparate Sites after Use of Whole-Cell Vaccine Genetically Modified to Release Sargramostim (2006)

A patient with recurrent breast cancer metastases following initial response to chemotherapy and hormonal maintenance was treated with a whole-cell tumor vaccine, resulting in a prompt objective complete remission of a lung lesion on computed tomography (CT) scans and near-complete regression of multiple breast lesions on magnetic resonance imaging (MRI). Three months after completion of the protocol, metastases were again found in the breast and lung, with new lesions in the brain and liver. Reinstitution of vaccine inoculation resulted in major regression of the brain and breast lesions, improvement in all other areas, and no indication of new lesions. Therapy consisted of inoculation of 20 x 10(6) SV-BR-1-GM cells, a unique breast cancer cell line transfected to release sargramostim (granulocyte macrophage colony-stimulating factor [GM-CSF]). Following lethal irradiation to 200 cGy, vaccine was injected intradermally in four divided doses to the back and thighs, every 2 weeks x 3, then every month x 3. Each treatment was preceded 48 hours earlier with low-dose cyclophosphamide 300 mg/m2 to abrogate regulatory T-cell activity. Interferon (IFN)-alpha, 20,000 IU, was injected into each inoculation site at 48 and 96 hours postinoculation to provide an additional "danger signal." The patient developed positive delayed-type hypersensitivity responses and also antibody reactivity to the vaccine cells.
Temperature rising elution fractionation and characterization of ethylene/octene-1 copolymers synthesized with constrained geometry catalyst (1999)

We report here the fractionation and characterization of two crystalline ethylene/octene-1 copolymer samples with octene-1 mole fractions of 0.028 and 0.089, synthesized in a solution continuous stirred-tank reactor (CSTR) using a constrained geometry catalyst (CGC) system. The samples were fractionated by preparative temperature rising elution fractionation (TREF), and the fractions were characterized by 13C NMR, GPC and DSC. The copolymers were found to have narrow TREF curves, indicating the CGC system produces copolymers with narrow composition distributions. The fractionation was mainly determined by the short chain branching density in the copolymers. The polymer molecular weight also showed an effect on the fractionation for the copolymer with octene-1 mole fraction of 0.028. The first-order Markovian statistical model appeared to be more valid in predicting the comonomer dyad and triad distributions in the copolymer fractions. The combination of TREF and GPC was found to be an effective technique for the analysis of copolymers with low crystallinity.
Isogenic Strain Construction and Gene Targeting in <i>Candida dubliniensis</i> (2001)

Candida dubliniensis is a recently described opportunistic fungal pathogen that is closely related to Candida albicans but differs from it with respect to epidemiology, certain virulence characteristics, and the ability to develop fluconazole resistance in vitro. A comparison of C. albicans and C. dubliniensis at the molecular level should therefore provide clues about the mechanisms used by these two species to adapt to their human host. In contrast to C. albicans, no auxotrophic C. dubliniensis strains are available for genetic manipulations. Therefore, we constructed homozygous ura3 mutants from a C. dubliniensis wild-type isolate by targeted gene deletion. The two URA3 alleles were sequentially inactivated using the MPA(R)-flipping strategy, which is based on the selection of integrative transformants carrying a mycophenolic acid resistance marker that is subsequently deleted again by site-specific, FLP-mediated recombination. The URA3 gene from C. albicans (CaURA3) was then used as a selection marker for targeted integration of a fusion between the C. dubliniensis MDR1 (CdMDR1) promoter and a C. albicans-adapted GFP reporter gene. Uridine-prototrophic transformants were obtained with high frequency, and all transformants of two independent ura3-negative parent strains had correctly integrated the reporter gene fusion into the CdMDR1 locus, demonstrating that the CaURA3 gene can be used for efficient and specific targeting of recombinant DNA into the C. dubliniensis genome. Transformants carrying the reporter gene fusion did not exhibit detectable fluorescence during growth in yeast extract-peptone-dextrose medium in vitro, suggesting that CdMDR1 is not significantly expressed under these conditions. Fluconazole had no effect on MDR1 expression, but the addition of the drug benomyl strongly activated the reporter gene fusion in a dose-dependent fashion, demonstrating that the CdMDR1 gene, which encodes an efflux pump mediating resistance to toxic compounds, is induced by the presence of certain drugs.
Distributed components for retrieval of driver's license data using a handheld computer. (2004)

The Project54 system allows the integration of electronic devices in police cruisers. Both the software and the hardware system architecture are modular. The software is composed of components running on an embedded computer and distributed components deployed on a handheld computer. The hardware architecture utilizes an in-car serial bus to connect various in-car electronic devices and a wireless connection to allow interaction between the handheld computer and the in-car computer. This general framework was used to integrate a twodimensional barcode scanner into the system. The barcode scanner is physically connected to the handheld computer. Once integrated into the system the barcode scanner is used synergistically with the in-car digital radio to allow officers to efficiently and safely perform records queries.
Displaying Uncertainty: Investigating the Effects of Display Format and Specificity (2005)

We conducted four studies regarding the representation of probabilistic information. Experiments 1 through 3 compared performance on a simulated stock purchase task, in which information regarding stock profitability was probabilistic. Two variables were manipulated: display format for probabilistic information (blurred and colored icons, linguistic phrases, numeric expressions, and combinations) and specificity level (in which the number and size of discrete steps into which the probabilistic information was mapped differed). Results indicated few performance differences attributable to display format; however, performance did improve with greater specificity. Experiment 4, in which participants generated membership functions corresponding to three display formats, found a high degree of similarity in functions across formats and participants and a strong relationship between the shape of the membership function and the intended meaning of the representation. These results indicate that participants can successfully interpret nonnumeric representations of uncertainty and can use such representations in a manner similar to the way numeric expressions are used in a decision-making task. Actual or potential applications of this research include the use of graphical representations of uncertainty in systems such as command and control and situation displays.
Coupling Between Flexible Ship and Liquid Sloshing Using Potential Flow Analysis (2010)

The significant increase in demand for Liquefied Natural Gas (LNG) and the economic aspects of its transportation resulted in increases in the number and size of LNG carriers. One of the design issues for LNG carriers is the sloshing phenomenon because containment systems widely used nowadays have no internal structures. Furthermore, because the weights of ship and cargo are comparable and ship operators want more flexible operations allowing partial fillings in tanks, the coupling effect between ship motions and sloshing requires further investigation, including the effect of ship distortion. The previous study on coupling between rigid body and sloshing shows good agreement between methods of prediction and measurements [1,2]. Hence, in this paper the potential flow approach adopted for the coupling effect between rigid body ship motion and sloshing is extended to flexible ship-partially filled tank system, using the desingularised Rankine source method. In this case, the global deflection of the flexible ship is used for application of the body boundary condition on the partially filled tank. The aim of this paper is to investigate the influence of hull flexibility on the hydrodynamic forces and moments associated with liquid sloshing and vice versa, as well as the dynamic characteristics (e.g. resonance frequencies) of the whole system. As there are no experimental results available, the method is validated by comparing hydrodynamic forces from sloshing obtained using rigid and flexible body approaches. The coupling effect between flexible ship and sloshing in partially filled tanks is investigated for an idealized LNG Carrier in beam regular waves, considering different partial filling scenarios.
HISTAMINE RECEPTORS IN THE HUMAN NOSE (1994)

The aim of this study was to determine the role of histamine receptors in the nose. The effects of intranasal histamine challenge were compared with those of a specific H1-receptor agonist, betahistine and a specific H2-receptor agonist, impromidine, in 11 normal individuals and four with rhinitis. Sneezing, nasal irritation and hypersecretion were induced by histamine and the H1-receptor agonist, betahistine only. Nasal airway resistance (Rna) was measured by passive anterior rhinomanometry. Histamine, betahistine and impromidine all induced rises in Rna in both normal individuals and those with rhinitis but histamine had the most potent effect; the H2-receptor effect on Rna was predominant over that of the H1-receptor. The sensitivity to all three agonists was greater in the individuals with rhinitis.