gebhart/patrepeval huggingface dataset:
Effect of local warming on hand and finger artery blood velocities (1995)

The effect of local heating on blood velocities in arteries supplying the skin of hand and fingers was studied in subjects kept in their thermoneutral zone. The temperature of one hand was steadily raised from 35 to 43 degrees C in 15 min, whereas the control hand was kept in the air or immersed in a water bath at 35 degrees C. Simultaneous blood velocity recordings from the two hands were made continuously using ultrasound Doppler. In the heated hand, a general rise in blood velocity level was seen. However, the spontaneous fluctuations in blood velocity assumed to be caused by synchronous vasomotor activity of the arteriovenous anastomoses (AVAs) remained unchanged and closely correlated with those in the control hand throughout the experiment. Thus the central nervous control of AVA vasomotion seems to be unaffected by local heating. The elevation of blood velocity in the heated hand is probably due to dilatation of other parts of the vascular bed, e.g., ordinary arterioles in the skin. Earlier investigators, using venous occlusion plethysmography, have reported vasoconstriction in the locally heated human finger. No sign of such heat-induced vasoconstriction was found in this study.
A high power Ge n-i-p waveguide photodetector on silicon-on-insulator substrate (2009)

We demonstrate high current operation of an evanescently coupled Ge waveguide photodetector grown on top of a Si rib waveguide. A 7.4 mum times 500 mum photodetector was found to dissipate 1.003 W of power (125.49 mA at -8V).
Adiabatic bond charge model for the phonons in diamond, Si, Ge, and<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>α</mml:mi><mml:mo>−</mml:mo><mml:mi mathvariant="normal">Sn</mml:mi></mml:math> (1977)

An adiabatic bond charge model (BCM) for the lattice dynamics of diamond-type crystals is developed. Our BCM unites elements of earlier models by Phillips and Martin, Keating, and Cochran. Four types of interactions are used: (a) central ion-ion forces, (b) Coulomb interactions of the ions and bond charges (BC's), (c) central ion-BC forces, and (d) bond-bending forces. These interactions represent the metal-like (a) and covalent (b)-(d) part of the crystal bonding. The phonon dispersion curves for Si, Ge, and $\ensuremath{\alpha}\ensuremath{-}\mathrm{Sn}$ are calculated using only four disposable parameters; for diamond, five parameters are employed. For all crystals, very good agreement with experiment is obtained. In particular, the typical flattening of the transverse acoustic phonons in the semiconducting materials is understood as a consequence of the adiabatic motion of the BC's, when the effective ion-BC coupling (b)+(c) is weak compared to the bond-bending forces (d). In an alternative representation of the BCM, the interactions (b) and (c) are replaced by central and noncentral ion-BC-ion potentials along one bond. The remaining long-range part of the Coulomb forces is unimportant; therefore, all essential interactions of the BCM are of very short range. Furthermore, the interaction parameters follow clear trends from diamond to $\ensuremath{\alpha}\ensuremath{-}\mathrm{Sn}$: type (a) increases, whereas types (b)-(d) decrease, especially the ion-BC coupling tends to vanish toward $\ensuremath{\alpha}\ensuremath{-}\mathrm{Sn}$.
Alkylation of Isobutane with Various Olefins in the Presence of Sulfuric Acid (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAlkylation of Isobutane with Various Olefins in the Presence of Sulfuric AcidR. J. Shlegeris and L. F. AlbrightCite this: Ind. Eng. Chem. Process Des. Dev. 1969, 8, 1, 92–98Publication Date (Print):January 1, 1969Publication History Published online1 May 2002Published inissue 1 January 1969https://pubs.acs.org/doi/10.1021/i260029a016https://doi.org/10.1021/i260029a016research-articleACS PublicationsRequest reuse permissionsArticle Views250Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Cytolytic T lymphocyte and antibody responses to synthetic peptides of influenza virus hemagglutinin. (1984)

Two peptides corresponding to HA1(181-204) and HA2(103-123) of the A/Japan/305/57 influenza virus hemagglutinin (HA) were chemically synthesized by solid-phase methods and were tested for their ability to generate murine secondary anti-influenza cytolytic T lymphocytes (CTL) in vitro and to bind monoclonal anti-HA antibodies. Peptide HA1(181-204) could only generate CTL in the presence of helper factors contained in supernatant fluids from either Concanavalin A-stimulated mouse spleen cultures or WEHI-3 cells grown in vitro. Peptide HA2(103-123) stimulated the induction of anti-influenza CTL independent of helper factors, but the stimulation was also greatly increased if helper factors were added. A 10-fold molar excess of peptide HA2(103-123) was required to obtain optimal CTL activation over the quantities required in the HA1(181-204) system. This molar ratio remained unchanged, even in the presence of helper factors. Induction of influenza-specific CTL was antigen-dependent in both systems, even though some killing of noninfected target cells was also occasionally observed. Our results suggest that synthetic peptides can be recognized as antigenic determinants in the generation of H-2-restricted anti-viral CTL capable of killing appropriately infected target cells. The inability of peptide HA1(181-204) to generate sufficient help for CTL development suggests that certain regions of the HA can be recognized by CTL precursors, but not by all of the required helper cells. Peptide HA1(181-204) also reacted with three monoclonal anti-HA antibodies as well as mouse anti-influenza (A/Japan/305/57) immune sera. This antibody reactivity suggests the possibility of a shared antigenic epitope or region between T and B cells, and therefore provides new insight in our understanding of viral antigenicity.
<i>Staphylococcus aureus</i>antigens and challenges in vaccine development (2008)

Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in humans and animals, as well as mastitis in dairy cattle. Methicillin-resistant S. aureus is increasingly recognized as a cause of staphylococcal infection and, therefore, immunotherapeutics have received new interest in both human and veterinary medicine. Vaccines aimed at preventing S. aureus infection in humans and mastitis in dairy cattle have been studied for many years. While some formulations have shown promise in ameliorating clinical disease, few, if any, of the S. aureus vaccines developed have adequately prevented new infection. The antigens targeted by S. aureus vaccines and potential reasons for the lack of success of vaccination against S. aureus are reviewed in this article.
Optimization of optical flow for scalable coding (2015)

Optical flow or dense motion field representations provide an alternative to block based schemes and are capable of describing smooth motion flows without introducing any artificial block boundaries. However dense motion fields have not been widely adopted for video coding applications principally due to the prohibitive cost of communicating such detailed motion representations. In this paper our focus is on estimating dense motion fields subject to R-D constraints derived from wavelet based coding of the motion data. We develop a probabilistic framework for estimating dense motion fields that is capable of evaluating the tradeoff between sparsity in the transformed domain and motion compensated distortion. R-D results show that we are able to improve upon traditional optical flow descriptions.
A context-aware experience sampling tool (2003)

A new software tool for user-interface development and assessment of ubiquitous computing applications is available for CHI researchers. The software permits researchers to use common PDA mobile computing devices for experience sampling studies. The basic tool offers options not currently available in any other open-source sampling package. However, the tool also has new functionality: context-aware experience sampling. This feature permits researchers to acquire feedback from users in particular situations that are detected by sensors connected to a mobile computing device.
Designing a Processor in Bluespec (2005)

In this thesis, we designed a 2-way out-of-order processor in Bluespec implementing the MIPS I integer ISA. A number of scheduling optimizations were then used to bring the initial design up to the same level of cycle-level concurrency as found in standard RTL-level designs. From this, a general design methodology is proposed to effectively express, debug, and optimize large Bluespec designs.
In vitro microdialysis membrane efficiency of broad-spectrum antibiotics in combination and alone (2014)

Differences among in vitro recovery by loss suggest two-drug combinations may impact dialysate recovery during in vivo retrodialysis procedures, particularly when larger molecular weight drugs (ie, vancomycin) are involved. Importantly, there were no differences during gain experiments. In vitro studies, as performed here, should be conducted for each potential two-drug combination, prior to their combined use for in vivo retrodialysis.
THE PIRIA REACTION. I. THE OVER-ALL REACTION (1931)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE PIRIA REACTION. I. THE OVER-ALL REACTIONW. H. Hunter and Murray M. SprungCite this: J. Am. Chem. Soc. 1931, 53, 4, 1432–1443Publication Date (Print):April 1, 1931Publication History Published online1 May 2002Published inissue 1 April 1931https://pubs.acs.org/doi/10.1021/ja01355a037https://doi.org/10.1021/ja01355a037research-articleACS PublicationsRequest reuse permissionsArticle Views653Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Treatment of hypogonadal adolescent boys with long acting subcutaneous testosterone pellets (1997)

All boys preferred this mode of testosterone administration to intramuscular injections. Long acting subcutaneous testosterone pellets are safe, efficacious, well tolerated, and convenient, and result in normal physical growth and improved psychological outlook in adolescent hypogonadal boys.
Localization of the ATP-Sensitive K+ Channel Subunit Kir6.2 in Mouse Pancreas (1997)

Kir6.2, a member of the inward rectifier K+ channel family, is a component of the ATP-sensitive K+ (K[ATP]) channel considered to play a key role in glucose-induced insulin secretion. We studied the distribution of Kir6.2 in mouse pancreas at the cellular level. The sites of Kir6.2 mRNA expression were determined by in situ hybridization histochemistry with a digoxigenin (DIG)-labeled antisense cRNA probe. The hybridization signal was unevenly present throughout the islets of Langerhans, while no distinct signal was detected in exocrine acinar cells. This distribution was confirmed by another cRNA probe complementary to a different region of Kir6.2 mRNA. In situ hybridization and immunofluorescence staining of serial sections with the anti-insulin, the anti-glucagon, and the anti-somatostatin antibodies showed Kir6.2 mRNA to be present in alpha-, beta-, and delta-cells. Furthermore, immunofluorescence staining with antibody raised against Kir6.2 revealed that Kir6.2 protein is localized within the pancreatic islets and is not found in exocrine pancreas. Kir6.2 was further shown to be located together with insulin, glucagon, or somatostatin. The positive staining of Kir6.2 appeared concentrated along the contour of each islet cell, suggesting that Kir6.2 is at the plasma membrane of islet cells. These results suggest that Kir6.2, as a component of K(ATP) channels, is an important molecule in the regulation of all the release of insulin, glucagon, and somatostatin.
Heterotrimeric G proteins as fluoride targets in bone (review). (1999)

Fluoride is an acknowledged bone anabolic agent. Nevertheless, a narrow therapeutic window and the adverse effects at higher therapeutic doses prevent broad clinical application of fluoride for treatment of diseases of bone loss, such as osteoporosis. The cellular and molecular mechanisms of fluoride action are poorly understood. recent advances in the elucidation of signal transduction pathways induced by fluoride in osteoblastic cells are reviewed. Fluoride and traces of aluminum form a complex, fluoroaluminate, which stimulates cellular heterotrimeric G proteins. Such complex can form in food, drinking water and in the organism after administration of sodium fluoride. Fluoroaluminate crosses the cell membrane and directly binds to the membrane-associated inactive G alpha protein subunits. Within the G alpha subunit, fluoroaluminate occupies the position next to GDP. The resulting G alpha-GDP-AlF4- complex assumes an active state conformation, which resembles that of G alpha-GTP complex. Under physiological conditions, G alpha-GTP complex is formed upon activation of seven transmembrane receptors that couple to heterotrimeric G proteins. Both fluoroaluminate-activated and receptor-activated G alpha subunits are capable of transmitting intracellular signals that lead to cellular responses. In bone-forming cells osteoblasts, fluoroaluminate stimulates pertussis toxin-sensitive G alpha i proteins. G alpha i activation leads to the reduction in cAMP (cyclic adenosine monophosphate) levels and to the activation of mitogen activated protein kinases, Erks (extracellular signal-regulated kinases) and p70 S6 kinase. These kinases are involved in the regulation of gene transcription and protein syntheses. Fluoroaluminate also stimulates pertussis toxin-insensitive proteins. Pertussis toxin-insensitive G proteins, most likely from G alpha 12 class, cause the activation of several cytoplasmic protein tyrosine kinases [Src, Pyk2 (proline-rich tyrosine kinase 2), and Fak (focal adhesion kinase)]. Activation of Erks can lead to osteoblast proliferation and differentiation, while activation of Src, Pyk2 and Fak can modulate the adhesion properties of osteoblasts. Osteoblast adhesion may, in turn, influence differentiation, migration, and apoptosis of these cells. The susceptibility of osteoblasts to fluoroaluminate can be achieved by their specific cellular context and by the rigidity of the surrounding bone tissue. In particular, higher levels of G alpha i proteins and of certain focal adhesion proteins are expressed by osteoblastic rather than by fibroblastic cells. The rigidity of adhesion substratum of osteoblasts may signal on its own and potentiate the signaling by fluoroaluminate. The information on mechanisms of intracellular signaling by fluoroaluminate can be utilized to identify a fluoroaluminate mimic, a drug that exhibits anabolic action on bone with a broader therapeutic range and less adverse effects than fluoride.
Range-velocity mitigation via SZ phase coding for NEXRAD WSR-88D radars (2004)

A fundamental limitation of pulsed weather radar is range-velocity ambiguity. Increasing (decreasing) the PRT (pulse repetition time) increases (decreases) the unambiguous range while decreasing (increasing) the unambiguous velocity. It has recently been shown that SZ phase coding of the transmit pulses allows for increased unambiguous range while maintaining a constant unambiguous velocity. To date statistical SZ phase coding performance has been investigated using numerically simulated Gaussian shaped weather spectra. However, experimental weather spectra are frequently non-Gaussian in shape, and thus SZ performance evaluation with experimental data would be more realistic. In this paper SZ phase coding is applied to experimental data offline and the results are compared to numerical simulations.
Towards a comprehensive framework for movement and distortion correction of diffusion MR images: Within volume movement (2017)

Most motion correction methods work by aligning a set of volumes together, or to a volume that represents a reference location. These are based on an implicit assumption that the subject remains motionless during the several seconds it takes to acquire all slices in a volume, and that any movement occurs in the brief moment between acquiring the last slice of one volume and the first slice of the next. This is clearly an approximation that can be more or less good depending on how long it takes to acquire one volume and in how rapidly the subject moves. In this paper we present a method that increases the temporal resolution of the motion correction by modelling movement as a piecewise continous function over time. This intra-volume movement correction is implemented within a previously presented framework that simultaneously estimates distortions, movement and movement-induced signal dropout. We validate the method on highly realistic simulated data containing all of these effects. It is demonstrated that we can estimate the true movement with high accuracy, and that scalar parameters derived from the data, such as fractional anisotropy, are estimated with greater fidelity when data has been corrected for intra-volume movement. Importantly, we also show that the difference in fidelity between data affected by different amounts of movement is much reduced when taking intra-volume movement into account. Additional validation was performed on data from a healthy volunteer scanned when lying still and when performing deliberate movements. We show an increased correspondence between the "still" and the "movement" data when the latter is corrected for intra-volume movement. Finally we demonstrate a big reduction in the telltale signs of intra-volume movement in data acquired on elderly subjects.
Increase of Glutamate Uptake in Astrocytes  (1997)

The increase of glutamate uptake by astrocytes in the presence of volatile anesthetics potentially attenuates excitatory synaptic transmission in the entire central nervous system, a finding that may explain in part the action of volatile anesthetics.
Structural and mechanistic studies on the photolysis of dialkylphenacylsulfonium salt cationic photoinitiators (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural and mechanistic studies on the photolysis of dialkylphenacylsulfonium salt cationic photoinitiatorsJames V. Crivello and J. L. LeeCite this: Macromolecules 1983, 16, 6, 864–870Publication Date (Print):June 1, 1983Publication History Published online1 May 2002Published inissue 1 June 1983https://pubs.acs.org/doi/10.1021/ma00240a006https://doi.org/10.1021/ma00240a006research-articleACS PublicationsRequest reuse permissionsArticle Views247Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Implementation of GA-trained GRNN for Intelligent Fast Charger for Ni-Cd Batteries (2006)

This paper presents the development of an intelligent genetic algorithm (GA) technique for training of a generalized regression neural network (GRNN) controller to achieve a compact network and to decrease battery charging time on a cost-effective RISC microcontroller. The suitable input-output data were selected from GA mechanism to establish GRNN. The computational complexity of GRNN can be reduced replaced by some simple polynomial forms. As a consequence, the fast charging device for nickel-cadmium (Ni-Cd) batteries can be efficiently implemented on a low-cost 16F876A RISC microcontroller. Experimental results are shown to demonstrate superiority of the proposed system
The properties of SiC in comparison with Si semiconductor devices (2013)

The SiC - silicon carbide MOSFET has exclusive features thanks its become better switch than Si - silicon semiconductor switch. There are some special features that need to be understood for use to in full devices potential. The advantages and differences of SiC MOSFETs have been described in this article in compare with Si IGBT transistor.
2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS) (2019)

International audience