gebhart/patrepeval huggingface dataset:
Multicell converters: derived topologies (2002)

Multicell converters were introduced ten years ago and, over this period, their properties have been thoroughly analyzed. Since then, this concept has lead to some other innovative topologies which are briefly presented in this paper. Different ways to introduce soft switching in multicell converters are investigated. The concept of distributing power over several switches, giving more degrees of freedom and using less passive components, is extended further with the stacked multicell topology. Finally, direct AC-AC converters using the multicell approach are described.
ADAM12/Syndecan-4 Signaling Promotes β1Integrin-dependent Cell Spreading through Protein Kinase Cα and RhoA (2003)

The ADAMs (a disintegrin and metalloprotease) comprise a large family of multidomain proteins with cell-binding and metalloprotease activities. The ADAM12 cysteine-rich domain (rADAM12-cys) supports cell attachment using syndecan-4 as a primary cell surface receptor that subsequently triggers beta(1) integrin-dependent cell spreading, stress fiber assembly, and focal adhesion formation. This process contrasts with cell adhesion on fibronectin, which is integrin-initiated but syndecan-4-dependent. In the present study, we investigated ADAM12/syndecan-4 signaling leading to cell spreading and stress fiber formation. We demonstrate that syndecan-4, when present in significant amounts, promotes beta(1) integrin-dependent cell spreading and stress fiber formation in response to rADAM12-cys. A mutant form of syndecan-4 deficient in protein kinase C (PKC)alpha activation or a different member of the syndecan family, syndecan-2, was unable to promote cell spreading. GF109203X and Gö6976, inhibitors of PKC, completely inhibited ADAM12/syndecan-4-induced cell spreading. Expression of syndecan-4, but not syn4DeltaI, resulted in the accumulation of activated beta(1) integrins at the cell periphery in Chinese hamster ovary beta1 cells as revealed by 12G10 staining. Further, expression of myristoylated, constitutively active PKCalpha resulted in beta(1) integrin-dependent cell spreading, but additional activation of RhoA was required to induce stress fiber formation. In summary, these data provide novel insights into syndecan-4 signaling. Syndecan-4 can promote cell spreading in a beta(1) integrin-dependent fashion through PKCalpha and RhoA, and PKCalpha and RhoA likely function in separate pathways.
Activation barriers to strain relaxation in lattice-mismatched epitaxy (1989)

We study the activation barriers to strain relaxation in metastable ${\mathrm{Ge}}_{0.25}$${\mathrm{Si}}_{0.75}$/Si(100) films by in situ annealing in a transmission electron microscope, observing in real time the dynamic relaxation events of misfit-dislocation nucleation, propagation, and interaction as a function of the sample annealing temperature. Activation energies for misfit-dislocation nucleation and propagation are obtained, and it is firmly established that both these processes and dislocation interactions inhibit strain relaxation in ${\mathrm{Ge}}_{\mathrm{x}}$${\mathrm{Si}}_{1\mathrm{\ensuremath{-}}\mathrm{x}}$/Si epitaxy.
Sceletium alkaloids. IV. Biosynthesis of mesembrine and related alkaloids. Amino acid precursors (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSceletium alkaloids. IV. Biosynthesis of mesembrine and related alkaloids. Amino acid precursorsP. W. Jeffs, W. C. Archie, Richard L. Hawks, and D. S. FarrierCite this: J. Am. Chem. Soc. 1971, 93, 15, 3752–3758Publication Date (Print):July 1, 1971Publication History Published online1 May 2002Published inissue 1 July 1971https://pubs.acs.org/doi/10.1021/ja00744a032https://doi.org/10.1021/ja00744a032research-articleACS PublicationsRequest reuse permissionsArticle Views257Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A 0.18μm CMOS 2.1GHz Sub-sampling Receiver Front End with Fully Integrated Second- and Fourth-Order Q-Enhanced Filters (2007)

The implementation of a 0.18μm CMOS 2.1GHz sub-sampling receiver front end with fully integrated fourth-and second- order Q-enhanced LC filters is described. The use of an integrated fourth-order filter allows the amount of noise aliasing due to sub-sampling to be reduced and the bandwidth and roll-off factor to be independently controlled. When tuned to a high effective quality factor of 210, the front end has a measured bandwidth of 14MHz, a passband flatness of +/-0.4dB, a gain of 34dB and an input IP3 of -31.7dBm. The simulated noise figure of the front end is 7.12dB, which is lower than that of previously published sub-sampling front ends using off-chip inductors. The total power consumption of the front end is 28.5mA from a 1.8V supply.
On the security of public key protocols (1981)

Recently the use of public key encryption to provide secure network communication has received considerable attention. Such public key systems are usually effective against passive eavesdroppers, who merely tap the lines and try to decipher the message. It has been pointed out, however, that an improperly designed protocol could be vulnerable to an active saboteur, one who may impersonate another user or alter the message being transmitted. Several models are formulated in which the security of protocols can be discussed precisely. Algorithms and characteri-zations that can be used to determine protocol security in these models are given.
Specific inhibition of T lymphocyte coactivation by triggering integrin β 1 reveals convergence of β 1, β 2, and β 7 signaling pathways (1996)

T cell coactivation is a dynamic process subject to integrin-dependent positive and negative regulation. Costimulation of human peripheral blood T cells by CD3 mAb OKT3 in conjunction with anti-alpha 4 has been shown to be down-regulated by the anti-beta 1.1 epitope-specific mAb 18D3. As expected, maximal costimulation induced by alpha 4-specific mAb L25 was inhibited (70%) by the addition of soluble mAb 18D3. Surprisingly, soluble mAb 18D3 inhibited maximal proliferation induced by the costimulatory alpha 4 beta 7-specific mAb ACT-1 by 40%, thus demonstrating that one integrin subfamily can regulate the activity of another. To determine whether mAb 18D3 could regulate more than alpha 4-associated integrin-mediated costimulation, non-alpha 4 integrins were tested. mAb 18D3 inhibited maximal proliferation induced by alpha 4-specific mAb 3D6, and an alpha 4-specific mAb 16. This clearly demonstrates that a variety of integrin costimulatory molecules (of the beta 1, beta 2, and beta 7 subfamilies) can be regulated negatively by mAb 18D3. To analyze the specificity of this negative regulation, other cell surface costimulatory molecules were tested for susceptibility to mAb 18D3. Although Abs specific for CD4, CD26, CD28, CD44, CD45RA, or CD45RO were sufficient to activate T cells when co-immobilized with anti-CD3 mAb, all were refractory to the inhibitory effects of mAb 18D3. Inhibition of T cell activation directly correlated with diminished IL-2 production. This suggests that mAb 18D3 selectively regulates integrin-dependent T cell activation by delivering a negative effect at some common point utilized by various integrin subfamilies.
Calixarenes. 15. The formation of complexes of calixarenes with neutral organic molecules in solution (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCalixarenes. 15. The formation of complexes of calixarenes with neutral organic molecules in solutionLorenz J. Bauer and C. David GutscheCite this: J. Am. Chem. Soc. 1985, 107, 21, 6063–6069Publication Date (Print):October 1, 1985Publication History Published online1 May 2002Published inissue 1 October 1985https://pubs.acs.org/doi/10.1021/ja00307a040https://doi.org/10.1021/ja00307a040research-articleACS PublicationsRequest reuse permissionsArticle Views817Altmetric-Citations102LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Very Convenient and Efficient Purification Method for Fullerene (C60) with 5,11,17,23,29,35,41,47-Octa-<i>tert</i>-butylcalix[8]arene-49,50,51,52,53,54,55,56-octol (1994)

Abstract The gram-order of fullerene (C60) with 99.8 wt% purity was isolated from carbon soot by fractional precipitation with 5,11,17,23,29,35,41,47-octa-tert-butylcalix[8]arene-49,50,51,52,53,54,55,56-octol. This is a very convenient and efficient C60 purification method without any precious apparatus.
Molecular Epidemiology and Functional Assessment of Novel Allelic Variants of SLC26A4 in Non-Syndromic Hearing Loss Patients with Enlarged Vestibular Aqueduct in China (2012)

An overall description of the molecular epidemiological findings of SLC26A4 in China is provided. The functional assessment procedure can be applied to identification of pathogenicity of variants. These findings are valuable for genetic diagnosis, genetic counseling, prenatal testing and pre-implantation diagnosis in EVA families.
Synergy Between Trehalose and Hsp104 for Thermotolerance in <i>Saccharomyces cerevisiae</i> (1996)

Abstract We isolated a mutant strain unable to acquire heat shock resistance in stationary phase. Two mutations contributed to this phenotype. One mutation was at the TPS2locus, which encodes trehalose-6phosphate phosphatase. The mutant fails to make trehalose and accumulates trehalose-6-phosphate. The other mutation was at the HSP104 locus. Gene disruptions showed that tps2 and hsp104 null mutants each produced moderate heat shock sensitivity in stationary phase cells. The two mutations were synergistic and the double mutant had little or no stationary phase-induced heat shock resistance. The same effect was seen in the tps1 (trehalose-6phosphate synthase) hsp104 double mutant, suggesting that the extreme heat shock sensitivity was due mainly to a lack of trehalose rather than to the presence of trehalose-6 phosphate. However, accumulation of trehalose-6-phosphate did cause some phenotypes in the tps2 mutant, such as temperature sensitivity for growth. Finally, we isolated a high copy number suppressor of the temperature sensitivity of tps2, which we call PMU1, which reduced the levels of trehalose-6-phosphate in tps2 mutants. The encoded protein has a region homologous to the active site of phosphomutases.
HCNC: High Capacity Netlist Compare (2002)

The author describes HCNC (High Capacity Netlist Compare), a technique for netlist comparison that uses the natural hierarchy of the transistor circuit to significantly increase the capacity of traditional netlist comparison algorithms. Since the natural hierarchy of the circuit is used, HCNC does not require hierarchical information from the user. HCNC also has some desirable properties for error recovery. Results from the network comparison of several large industrial circuits shall show the viability of this algorithm.
Syntheses of Xanthofulvin and Vinaxanthone, Natural Products Enabling Spinal Cord Regeneration (2012)

Growth promoting: The first synthesis of the natural product xanthofulvin (SM-216289) has resolved issues regarding its structural assignment and that described for the natural product 411J. The structurally and biologically related natural product vinaxanthone was similarly prepared through a novel dimerization reaction. Treatment of C. elegans with synthetic xanthofulvin and vinaxanthone enhanced axonal branching. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Capturing micro-assembly process windows on process data sheets (2006)

This paper reports on an initiative which aims at capturing micro-assembly process window data. The idea originated in the EU funded thematic network Assembly-Net. The data is considered to be important for training, education and engineering purposes in industry and universities. The concept of Process Data Sheets is introduced, which is a structured form for capturing the process window data. The PDS is illustrated by examples from ongoing research activities at the authors' institutes
Repair of segmental defects in rabbit humeri with titanium fiber mesh cylinders containing recombinant human bone morphogenetic protein‐2 (rhBMP‐2) and a synthetic polymer (2002)

To develop a new technology that enhances the regeneration potential of bone and the repair of large intercalated defects in long bone, recombinant human bone morphogenetic protein-2 (BMP-2; 20 microg or 40 microg) was mixed in a polymer gel (poly-lactic acid-polyethyleneglycol block copolymer; PLA-PEG; 200 mg) and incorporated into titanium fiber-mesh cylinders. Three 5-mm cylinders were placed end-to-end to fill a 15-mm defect created in the humeri of adult rabbits and were stabilized by an intramedullary rod. In controls, the titanium fiber-mesh cylinders were combined with PLA-PEG in the absence of BMP. Six weeks after implantation, new bone had formed on the surface of the implant and had bridged the defect. All of the defects (5/5) treated by cylinders containing 120 microg (40 microg x 3) of BMP were repaired completely. New bone formation was also found inside the pores of the cylinders. The defect was not repaired in the control animals. These results demonstrate that these new composite implants fabricated by combining rhBMP, synthetic degradable polymers and compatible biomaterials enhance the regeneration potential of bone. Thus, it is possible that large skeletal defects can be repaired using this prosthesis in lieu of autogenous bone graft.
Gold(I) complexes with bidentate tertiary phosphine ligands: formation of annular vs. tetrahedral chelated complexes (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGold(I) complexes with bidentate tertiary phosphine ligands: formation of annular vs. tetrahedral chelated complexesSusan J. Berners-Price and Peter J. SadlerCite this: Inorg. Chem. 1986, 25, 21, 3822–3827Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://pubs.acs.org/doi/10.1021/ic00241a023https://doi.org/10.1021/ic00241a023research-articleACS PublicationsRequest reuse permissionsArticle Views802Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A fraud detection model: A must for auditors (2002)

This paper addresses a fundamental issue in financial regulation ‐ that of the auditor’s ability to detect material irregularities. If an auditor is to detect irregularities he/she must also be cognisant of fraud aetiology by drawing on such other disciplines as psychology, criminology and sociology. The paper first provides a critique of existing fraud aetiology models and then describes the ROP Fraud Risk‐Assessment Model constructed by the author in a study of convicted serious fraud offenders in Australia. The main concern of the paper is with the eclectic fraud detection model (EFD), of which the ROP model is a component. The EFD model is aimed at enhancing the auditor’s fraud detection ability, it has been constructed by the author and its utility successfully tested in Australia in a survey of auditors. Finally, the policy implications for auditors of the findings obtained are also considered.
Swiss roll nanomembranes with controlled proton diffusion as redox micro-supercapacitors (2010)

We demonstrate a redox Swiss roll micro-supercapacitor by rolling up a multilayered nanomembrane with an electrochemical active layer at either the outer or inner surface for different proton diffusion behaviors. The Swiss roll micro-supercapacitor could achieve high performance (e.g. capacity and life time) in a microscale power source and is helpful for studying charge transfer at the electrolyte/electrode interface.
Reduction mechanism of surface oxide in aluminum alloy powders containing magnesium studied by x-ray photoelectron spectroscopy using synchrotron radiation (1997)

We investigated the reduction mechanism of surface oxide on aluminum alloy powders containing magnesium, by x-ray photoelectron spectroscopy using synchrotron radiation (SR-XPS). The reduction is the initial reaction in a new aluminum nitridation method developed by one of the authors. In heating the powders to 823 K, magnesium soluted in the powders moves from the inner region to the surface at temperatures below 573 K, and finally, above 773 K, the magnesium reduces the aluminum oxide of powder surfaces by chemical reaction, which breaks the surface oxide films, and metallic aluminum appears on the topmost surface of the powders. These results suggest that the SR-XPS system is very useful for dynamic chemical reaction analysis of the surface via in situ measurement.
Laser-Raman Spectroscopic Study of the Adhesive Interface Between 4-MET/MMA-TBB Resin and Hydroxyapatite or Bovine Enamel (1991)

The possible chemical interaction between synthetic hydroxyapatite or bovine enamel and a functional monomer of 4-methacryloxyethyl trimellitic acid (4-MET) diluted in methyl methacrylate (MMA) was examined by measuring the Raman spectra. It was concluded that the carboxyl group of 4-MET reacted with the calcium in the substrate to form a salt that was detected by the Raman band at around 1,380 cm-1. However, formation of the salt on the surface of the hydroxyapatite (HAP) with the carboxyl group, and polymerization of the 4-MET in the methacryl group near the surface were mutually exclusive reactions for the same 4-MET molecule.
Design of Question Answering System with Automated Question Generation (2008)

One of the most difficult problems in developing question-answering (QA) system is that it is so hard to generate natural language questions and to find an answer to a query question. In order to avoid a number of difficulties of developing QA systems, we propose a new style of question-answering system architecture that actively uses sentences within a document as a source of question/answer. Basically, our proposed QA system gives user a set of candidate query question for user information needs, and the candidate questions are automatically generated from significant sentences that are expected to contain meaningful facts or events. The QA system builds a complete database of (question, answer) pairs after analyzing a whole collection of documents. For this, we need to perform the following steps: sentence split, named-entity recognition, question generation, question filtering, question/ answer indexing. The important things in the process are question generation and question filtering. For the first thing, we can generate questions that ask the entities extracted from a given sentence. The question filtering is to isolate significant sentences that have meaningful information that users want.
Magazines and Vmem: Extending the Slab Allocator to Many CPUs and Arbitrary Resources (2001)

The slab allocator provides efficient object caching but has two significant limitations: its global locking doesn&apos;t scale to many CPUs, and the allocator can&apos;t manage resources other than kernel memory. To provide scalability we introduce a per-processor caching scheme called the magazine layer that provides linear scaling to any number of CPUs. To support more general resource allocation we introduce a new virtual memory allocator, vmem, which acts as a universal backing store for the slab allocator. Vmem is a complete general-purpose resource allocator in its own right, providing several important new services; it also appears to be the first resource allocator that can satisfy arbitrary-size allocations in constant time. Magazines and vmem have yielded performance gains exceeding 50% on system-level benchmarks like LADDIS and SPECweb99. We ported these technologies from kernel to user context and found that the resulting libumem outperforms the current best of breed user level memory allocators. libumem also provides a richer programming model and can be used to manage other user level resources.