gebhart/patrepeval huggingface dataset:
Topical applications of pyrethroid and organophosphate mixtures revealed positive interactions against pyrethroid-resistant Anopheles gambiae. (2004)

The efficacy of a binary mixture of bifenthrin (pyrethroid) and chlorpyrifos-methyl (organophosphate) has been tested against susceptible and pyrethroid-resistant strains of Anopheles gambiae Giles, the major malaria vector in sub-Saharan Africa. Dose-mortality regression lines were determined for each insecticide alone and in mixtures by topical applications on adult female mosquitoes. A combination index (CI) was used to quantify the interactions occurring between the pyrethroid and organophosphate insecticides. The results revealed synergism at high doses against both susceptible (0.7 > CI > 0.3) and pyrethroid-resistant (0.9 > CI > 0.7) An. gambiae. These results suggest that insecticide mixtures may be an alternative strategy for vector control, especially in areas where mosquitoes are resistant to pyrethroids.
A speeding-up method of parsing-stack operations for LR parsers (2002)

This paper presents a new method of LR parsing based on the distinction of stack states and non-stack states. Non-stack states are states which do not need to be pushed into the LR parsing stack and stack states are states to be pushed into it. By using some of the properties based on the stack-controlling LR parser defined, the parsing speed and the size of parsing tables can be improved, and the improvement includes the traditional method eliminating unit productions. By empirical observations for variety of programming languages, the efficiency is verified. An extension of the method to the generalized LR parsers for natural language is also discussed.
Structures and gas separation properties of asymmetric polysulfone membranes made by dry, wet, and dry/wet phase inversion (1991)

Abstract Integrally skinned asymmetric gas separation membranes were prepared by (i) dry, (ii) wet, and (iii) dry/wet phase inversion processes. The membranes were cast from a polysulfone/methylene chloride/1,1,2‐trichloroethane/2‐methyl‐2‐butanol casting system. Wet and dry/wet phase inversion membranes were quenched in methanol. Membranes made by dry/wet phase inversion using convective evaporation showed optimum gas separation performance. The average O 2 /N 2 and He/N 2 selectivities of these membranes were within 85% of those determined for a dense, solution‐cast polysulfone film, suggesting that the ultrathin skin layers were essentially defect free. The average apparent skin layer thickness of all samples tested was 270 Å. Scanning electron photomicrographs revealed that optimum membranes made by dry/wet phase inversion consist of an ultrathin skin layer, a tightly packed nodular transition layer, and an open‐cell, sponge‐like substructure. Dry/wet phase inversion membranes prepared by free‐standing evaporation resulted either in high flux and low selectivity membranes or essentially defect‐free membranes with fluxes lower than those made by convective evaporation. Dry‐phase inversion membranes exhibited extremely low gas fluxes due to thick (17.5 μm) skin layers. On the other hand, wet phase inversion membranes showed O 2 /N 2 selectivities < 1, indicating that gas transport was determined by pore flow through skin layer defects.
A fast parallel implementation of a Berlekamp-Massey algorithm for algebraic-geometric codes (1998)

We obtain a parallel Berlekamp-Massey-type algorithm for determining error locating functions for the class of one point algebraic-geometric codes. The proposed algorithm has a regular and simple structure and is suitable for VLSI implementation. We give an outline for an implementation, which uses as main blocks /spl gamma/ copies of a modified one-dimensional Berlekamp-Massey algorithm, where /spl gamma/ is the order of the first nongap in the function space associated with the code. Such a parallel implementation determines the error locator for an algebraic-geometric code using the same time requirements as the underlying one-dimensional Berlekamp-Massey algorithm applied to the decoding of Reed-Solomon codes.
A High Near-Infrared Sensitivity Over 70-dB SNR CMOS Image Sensor With Lateral Overflow Integration Trench Capacitor (2020)

This article presents a 16-μm pitch CMOS image sensor (CIS) exhibiting a high near-infrared (NIR) sensitivity and a 71.3-dB signal-to-noise ratio (SNR) with a linear response for high-precision absorption imaging. A 1.6-pF lateral overflow integration trench capacitor (LOFITreC) was introduced in each pixel to achieve a very high full well capacity (FWC), and a very low impurity concentration p-type Cz-Si substrate with a low oxygen concentration was employed for improving the NIR sensitivity. The developed CIS operated at a single exposure linear response wide dynamic range (DR) mode and a dual reset voltage mode for high SNR absorption imaging and achieved the maximum 24.3 Me <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> FWC, a wide spectral sensitivity from 200 to 1100 nm, and a photodiode quantum efficiency of 89.7%, 78.2%, and 26.7% at 860, 940, and 1050 nm, respectively. Both the spatial resolution and light sensitivity toward the NIR light were further improved by thinning the Si substrate and by applying a negative backside bias. Due to the LOFITreC, a record spatial efficiency of 95 ke <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> /μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> with a 130-dB DR was achieved. As one of the applications of the developed CIS, the NIR absorption imaging toward a noninvasive blood glucose measurement was experimented and a diffusion of 5 mg/dl glucose was clearly visualized at 1050 nm in real time.
Lithium Extraction Mechanism from α-Spodumene by Fluorine Chemical Method (2012)

In order to decrease lithium extraction cost, pollution and energy. A new and efficient technology was particularly discussed in this paper, the fluorine chemical method to extract lithium from spodumene. The reaction mechanism had also been analysed by studying the crystal structure variation and reaction products. The results show that hydrofluoric acid corroded α-spodumene in low temperature, damaged the compact chemical bonds: Li-O, Al-O, Si-O, and Al-O-Si, and generated Li3AlF6 and AlF3, which can be dissolved in sulfuric acid. Our research provides theoretical guidance for the lithium extraction process from α-spodumene.
Ionic Liquids for CO<sub>2</sub> Capture and Emission Reduction (2010)

Ionic liquids, especially those functionalized with amine groups, show significant potential for a wide variety of CO2 separations, including postcombustion CO2 capture. By tethering the amine to the anion, the stoichiometry of the reaction can be doubled from one CO2 for every two amines (as is the case with aqueous monoethanolamine) to one CO2 for each amine. Moreover, the reaction enthalpy can be actively tuned by the design of the anion, adjusting capacity and regeneration energy. In addition, ILs can be used without added water, further reducing the parasitic energy required for CO2 removal from flue gas.
Lactotransferrin Gene Expression in the Mouse Uterus and Mammary Gland (1989)

The mouse mammary gland and uterus expressed the gene for the secretory protein lactotransferrin under various physiological conditions. Lactotransferrin, however, was induced by estrogen in a time- and dose-dependent fashion in the uterus of the immature mouse, but was not affected by estrogen in the mammary gland. Differences were also found in the expression of lactotransferrin in mammary glands and uteri of adult females during lactation. A high level of the protein was detected by immunocytochemistry in uterine epithelial cells 1 day after parturition, but immunoreactivity disappeared quickly thereafter. Lactotransferrin message was, however, relatively abundant in the mammary gland at the end of the lactation period. The presence of lactotransferrin in various tissues also was investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analysis. Two forms of immunoreactive material was detected by this method; a 70K band was found in uterine luminal fluid from the estrogen-stimulated immature mouse and in homogenates of lung, vagina, mammary gland, oviduct, spleen, lymph node, and uterus of the adult female mouse, and a 65K band was detected in submaxillary gland, kidney, ovary, and all of the above tissues. Brain and duodenum had no detectable immunoreactive material. A transient appearance of lactotransferrin was observed in the uterine luminal fluid of pseudopregnant mice. These changes in the level of lactotransferrin in the uterus and mammary gland under various physiological conditions suggest that the regulation of this protein's expression is tissue specific.
Erythropoietin-dependent and erythropoietin-independent enhancement of colony formation by immature erythroid progenitors (BFUe). (1983)

The erythropoietin (epo)-dependent burst forming activities (BFA) of foetal calf serum (FCS), mouse bone marrow cells (BFA-cell) and lectin-stimulated mouse spleen conditioned medium (BFA-mscm) were investigated. Burst enhancement by BFA-mscm was independent of FCS concentration above 5% FCS. The activity of BFA-cell was directly proportional to FCS concentration. There was a high correlation for the relationship between the logarithm of total cell concentration and the logarithm of burst number for each concentration of FCS. Burst formation in the presence of BFA-cell showed a high epo requirement whereas plateau numbers of bursts were evident at concentrations of 1 to 2 units of epo/ml in cultures containing BFA-mscm. The epo-independent developmental activities (EIDA) of BFA-cell and BFA-mscm were examined in methylcellulose cultures to which the addition of epo was delayed for up to four days. Under all conditions examined, the number of bursts formed in the presence of BFA-cell declined with increasing delay of epo addition. Studies on the kinetics of haemoglobin synthesis in such experiments demonstrated that this decline in colony number was associated with a delay in haemoglobin synthesis. Burst formation in cultures containing various levels of BFA-mscm was independent of the time of epo addition. These results indicate that the burst enhancing ability of BFA-mscm is directly related to its EIDA whereas bone marrow cells appear to lack this activity.
Dimerization: a versatile switch for oncogenesis (2004)

Forced dimerization or oligomerization has emerged as a powerful mechanism for unleashing the oncogenic properties of chimeric transcription factors in acute leukemias. Fusion of transcriptional regulators with a variety of heterologous partner proteins as a consequence of chromosomal rearrangements induces inappropriate self-association, leading to aberrant transcriptional properties and leukemogenesis. Forced dimerization/oligomerization may alter the association of a DNA-binding protein for its transcriptional cofactors, or the dimerization motifs themselves may constitutively recruit transcriptional effector molecules. Oligomerized chimeras may also sequester essential partners or cofactors to exert dominant-negative effects on target gene expression. A key mechanistic feature, and one with major clinical implications, is the nature of the transcriptional cofactors that are recruited by the dimerized oncoprotein. Chimeric RARalpha and acute myeloid leukemia 1 (AML1) proteins induce constitutive repression after the recruitment of corepressors, whereas inappropriate maintenance of target gene expression by mixed-lineage leukemia (MLL) chimeras may result from the recruitment of coactivators or the basal transcriptional machinery. Molecular therapies directed at enzymatic activities of the aberrantly recruited cofactors, or antagonism of dimerization itself, represent promising avenues of current and future investigation.
Elastic Circuits (2009)

Elasticity in circuits and systems provides tolerance to variations in computation and communication delays. This paper presents a comprehensive overview of elastic circuits for those designers who are mainly familiar with synchronous design. Elasticity can be implemented both synchronously and asynchronously, although it was traditionally more often associated with asynchronous circuits. This paper shows that synchronous and asynchronous elastic circuits can be designed, analyzed, and optimized using similar techniques. Thus, choices between synchronous and asynchronous implementations are localized and deferred until late in the design process.
Efficient Chemical Introduction of a Disulfide Cross-Link and Conjugation Site into Human Hemoglobin at β-Lysine-82 Utilizing a Bifunctional Aminoacyl Phosphate (1997)

The creation of a cross-link containing a disulfide into hemoglobin has been accomplished with a site-directed reagent, N,N'-bis(Cbz-cystinyl)bis(methyl phosphate) (1). This is prepared from the reaction of the bis acid chloride of N-protected cystine with dimethyl phosphate followed by O-demethylation with methyl iodide in acetone. Reaction with deoxyhemoglobin produces two main products: cross-linked hemoglobin as the bis(cystinyl amide) of the epsilon-amino group of the side chain of Lys-82 of the two beta subunits as well as material that has each of the same amino groups modified as the cysteinyl amide but not cross-linked. Addition of 2-mercaptoethanol cleaves the disulfide in the material that is not cross-linked while leaving the disulfide intact in the cross-linked species. Dithiothreitol reduces the disulfide in the cross-linked species as well as in the species that is not cross-linked. Spontaneous oxidation in air converts all of the reduced material to the cross-linked bis(cystinyl amide) of hemoglobin. The reagent permits controlled introduction of cystinyl groups at lysyl residues, leading to formation of sulfhydryl groups by reduction and the possibility of re-forming the cross-links or forming conjugates.
Design of an adsorbent with an ideal pore structure for methane adsorption using metal complexes (2001)

Three-dimensional metal complexes synthesized from copper dicarboxylates and triethylenediamine (TED), which have an ideal pore size for methane adsorption, have higher methane adsorption capacity than the theoretical maximum for activated carbons.
The Effect of Addition of Fluorescent Moieties to Dihydropyrenes:  Enhancing Photochromicity and Fluorescence Monitoring (2007)

A series of dihydropyrenes with appending fluorescent moieties were synthesized with the objective of increasing the photochromic efficiency for this class of compounds and to establish how suitable fluorescence would be to follow their photochromic behavior. The ring opening quantum yields of dihydropyrenes with aroyl substituents at the 4-position showed increased ring opening quantum yields without a decrease of the half-life for the thermal reversion of the less stable open isomer, the metacyclophanediene to the dihydropyrene. The fluorescence of the appending naphthoyl or pyrenoyl moieties was not suitable to follow the photochromic cycling of the dihydropyrenes. However, the emission detected above 600 nm of the closed isomer of the dihydropyrene moiety was shown to be a good monitoring method for the photochromic cycling.
A technique for animating natural behaviour in complex scenes (2002)

An approach to the control of motion in computer animations is proposed. It is called relations, and is based on primitive motion elements plus hierarchical structuring mechanisms. By using the relation approach, the motion in an environment is decomposed into a set of independent relations, which can be separately modeled and later used as elements to compose sequential behaviors gradually in the environment. This approach uses a frame-based notation for relations and a three-layer control hierarchy for structuring the relations. The use of the relation approach is illustrated by a ballroom dance example in a dynamic room environment with multiple dancers and other moving objects.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Meeting report: Proteases, extracellular matrix, and cancer: an AACR Special Conference in Cancer Research. (2003)

Our view of the ECM [3][1] and its role in cancer has substantially evolved over the last decade. It is now apparent that the ECM is much more than a physical barrier against tumor invasion. It is an integral part of the tumor microenvironment and extensively modified by proteases during malignant
Robust Analog/RF Circuit Design With Projection-Based Performance Modeling (2007)

In this paper, a robust analog design (ROAD) tool for post-tuning (i.e., locally optimizing) analog/RF circuits is proposed. Starting from an initial design derived from hand analysis or analog circuit optimization based on simplified models, ROAD extracts accurate performance models via transistor-level simulation and iteratively improves the circuit performance by a sequence of geometric programming steps. Importantly, ROAD sets up all design constraints to include large-scale process and environmental variations, thereby facilitating the tradeoff between yield and performance. A crucial component of ROAD is a novel projection-based scheme for quadratic (both polynomial and posynomial) performance modeling, which allows our approach to scale well to large problem sizes. A key feature of this projection-based scheme is a new implicit power iteration algorithm to find the optimal projection space and extract the unknown model coefficients with robust convergence. The efficacy of ROAD is demonstrated on several circuit examples
Poem by sir E. Dyer (1850)

Journal Article Poem by sir E. Dyer Get access C. B. C. B. Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s1-II, Issue 32, 8 June 1850, Page 29, https://doi.org/10.1093/nq/s1-II.32.29a Published: 08 June 1850
The Steady-State Repertoire of Human SCF Ubiquitin Ligase Complexes Does Not Require Ongoing Nedd8 Conjugation (2010)

The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble with Skp1-Cul1-RING to serve as the substrate specificity subunit of an SCF ubiquitin ligase complex. SCF activity is switched on by conjugation of the ubiquitin-like protein Nedd8 to Cul1. Cycles of Nedd8 conjugation and deconjugation acting in conjunction with the Cul1-sequestering factor Cand1 are thought to control dynamic cycles of SCF assembly and disassembly, which would enable a dynamic equilibrium between the Cul1-RING catalytic core of SCF and the cellular repertoire of FBPs. To test this hypothesis, we determined the cellular composition of SCF complexes and evaluated the impact of Nedd8 conjugation on this steady-state. At least 42 FBPs assembled with Cul1 in HEK 293 cells, and the levels of Cul1-bound FBPs varied by over two orders of magnitude. Unexpectedly, quantitative mass spectrometry revealed that blockade of Nedd8 conjugation led to a modest increase, rather than a decrease, in the overall level of most SCF complexes. We suggest that multiple mechanisms including FBP dissociation and turnover cooperate to maintain the cellular pool of SCF ubiquitin ligases.
Architecture and protocols of the future European quantum key distribution network (2008)

Abstract A point‐to‐point quantum key distribution (QKD) system takes advantage of the laws of quantum physics to establish secret keys between two communicating parties. Compared to the classical methods, such as public‐key infrastructures, QKD offers unconditional security, which makes it attractive for very high security applications. However, this unprecedent level of security is mitigated by the inherent constraints of quantum communications, such as the limited rates and ranges of an individual point‐to‐point QKD link. A QKD network, which can be built by combining multiple point‐to‐point QKD devices, can alleviate the constraints and enable point‐to‐multi‐point key distribution based on QKD technology. The European project, secure communication based on quantum cryptography (SeCoQC) aims at deploying a prototype QKD network, which will be demonstrated in September 2008, by developing the architecture and the protocols, as well as the specific hardware for long‐range QKD networks. This paper discusses the important aspects of the architecture and the network layer protocols of the SeCoQC QKD network. Copyright © 2008 John Wiley & Sons, Ltd.
Perception-based motion planning for indoor exploration (2003)

This paper proposes an approach for motion planning in indoor environments based on incomplete and uncertain information from a line-based binocular stereo system. The primary goal of the planning process is to plan an optimal path through an unknown or partially known environment, depending on the information gained from exploration and the current mission goal. This paper presents an adaptable motion planner that supports sensor-based map construction, object recognition and navigation in an unknown environment while carrying out a mission. Also presented are some preliminary experimental results that demonstrate the utility of the approach.
Reaction of aminosulfur trifluorides with alcohols: inversion vs. retention (1996)

Reaction of aminosulfur trifluorides with alcohols replaces the hydroxy group with fluorine. A study with the cyclic secondary alcohols trans-2-bromoindan-1-ol (3), trans-2-methylcyclopentanol (7), cis-2-methylcyclopentanol (8), trans-[2-2H1]cyclopentanol (9), cis-[2-2H1]cyclopentanol (10) and trans-2-fluorocyclopentanol (11) gave primarily inversion of configuration via an SN1-like pathway. The product stereochemistry and alkene formation in the reaction of aminosulfur trifluorides with cyclopentanols was similar to the products of solvolysis of cyclopentyl tosylates in methanol. The stereochemistry of the fluoro products was confirmed by independent synthesis or assigned by 1H and 19F NMR spectral data except for the deuteriated products 14 and 15 whose stereochemistry was assigned by their 2H NMR data.
ChemInform Abstract: Stereoselective Synthesis of 1′‐C‐Branched Uracil Nucleosides from Uridine. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Functional activity monitoring from wearable sensor data (2005)

A novel approach is presented for the interpretation and use of EMG and accelerometer data to monitor, identify, and categorize functional motor activities in individuals whose movements are unscripted, unrestrained, and take place in the "real world". Our proposed solution provides a novel and practical way of conceptualizing physical activities that facilitates the deployment of modern signal processing and interpretation techniques to carry out activity monitoring. A hierarchical approach is adopted that is based upon: 1) blackboard and rule-based technology from artificial intelligence to support a process in which coarse-grained activity partitioning forms the context for finer-grained activity partitioning; 2) neural network technology to support initial activity classification; and 3) integrated processing and understanding of signals (IPUS) technology for revising the initial classifications to account for the high degrees of anticipated signal variability and overlap during freeform activity.