gebhart/patrepeval huggingface dataset:
Synthesis, characterization and antimicrobial study of substituted bis-[1 ,3,4]-oxadiazole, bis-[1 ,3,4]-thiadiazole and bis-[1,2,4]-triazole derivatives (2008)

Department of Chemistry, Shri Radhakisan Laxminarayan Toshniwal College of Science, Akola-444 001,<br> Maharashtra, India<br> <em>E-mail</em> : pradip22209l@yahoo.co.in<br> Postgraduate Department of Chemistry, Shri Shivaji Science College, Amravati-444 603, Maharashtra, India<br> <em>Manuscript received 29 April 2008, accepted 16 July 2008</em> Series of compounds 1,4-bis-(2-aryl/alky1-amino-[1,3,4]-oxadiazol-5-yI)-benzenes, 1,4-bis-(2-aryl/alkyl-amino[<br> 1,3,4]-thiadiazol-5-yl)-benzenes and 1,4-bis-(3-mercapto-4-aryl/alkyl-[1,2,4]-triazol-5-yl)-benzenes have been synthesized<br> by the oxidative cyclization of di-(<em>N</em>-aryl/alkyl thiocarbamido) terephthalamides using alkaline ethanolic solution of iodine<br> containing potassium iodide, <em>ortho</em>-phosphoric acid and aqueous potassium hydroxide solution respectively. These<br> compounds on acetylation afforded his-acetyl derivatives, on benzoylation afforded his-benzoyl derivatives and on reaction<br> with ethyl iodide afforded bis-ethylmercapto derivatives respectively. These compounds have been assayed for their<br> antimicrobial activity against gram-positive as well as gram-negative microorganisms.
Integrated shadow mask method for patterning small molecule organic semiconductors (2006)

We have developed a simple and efficient method for patterning small molecule semiconductors for applications in the field of organic electronics. In our approach, a profile is created using a single layer of photoresist, defining the regions where the organic semiconductor is to be deposited. Subsequent deposition of a small molecule semiconductor results in a discontinuity of the semiconductor film at the photoresist edge. The resulting transistor characteristics have an off current that is systematically below 1pA. We demonstrate both p-type and n-type organic thin-film transistors using this method, using pentacene and copper hexadecafluorophthalocyanine (F16CuPc), respectively.
Notes- A New Synthesis of Porphin (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNotes- A New Synthesis of PorphinStefan KrolCite this: J. Org. Chem. 1959, 24, 12, 2065–2067Publication Date (Print):December 1, 1959Publication History Published online18 July 2003Published inissue 1 December 1959https://pubs.acs.org/doi/10.1021/jo01094a635https://doi.org/10.1021/jo01094a635research-articleACS PublicationsRequest reuse permissionsArticle Views499Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A novel self-aligned AlGaAs laser with bent active layer grown by MOCVD (1985)

A novel self-aligned AlGaAs laser with bent active layer (SBA laser) grown by two-step MOCVD has been developed. The SBA laser has an inner current confinement stipe and the transverse mode is stabilized by a large effective refractive index step in the lateral direction provided by the steep bends of the active layer. As a result, low threshold current (28 mA) with high differential quantum efficiency (28%/facet), high characteristic temperature (210 K) and small astigmatism within a few microns have been achieved. The laser has also a long life.
Application security support in the operating system kernel (2006)

Application security is typically coded in the application. In kernelSec, we are investigating mechanisms to implement application security in an operating system kernel. The mechanisms are oriented towards providing authorization properties, and this goal drives the design of permissions and protection mechanisms.The resulting system is dynamic, allowing the set of permissions for a program to evolve during program execution. This reduces the need for users and applications to be aware of protection mechanism, since the protection mechanism provides the user with more freedom in how they do things. We explore these properties through a number of examples.KernelSec also supports a group (role) mechanism which can define constrained groups enabling groups which only grow, only shrink, are constant, are mutually exclusive with other groups, and which allow inheritance. Moreover groups are used to regulate group membership and allow group administration by non-privileged users.
Iterative MMSE Precoding for MIMO Interference Channel (2009)

In this paper, a novel precoding technique is proposed to improve the performance of the MIMO interference channel (MIC). Since the reachable sum-rate is a long-term problem, we present an iterative approach to improve the power-offset and achieve a higher sum-rate than the ordinary scheme. Considering the difference between MIC and multi-input multi-output (MIMO) system, we design joint precoding based on minimum mean square error (MMSE) by the Lagrangian multiplier method for the different transmitters, which is an iterative procedure to achieve the optimal structure. By setting a reasonable threshold for the iterative process, the effect of the crosstalk in MIC is removed significantly. Simulation results show the effectiveness of presented algorithm.
Application of PCR to the identification of dermatophyte fungi (2000)

Infection of the keratinised tissues (skin, hair and nails) in man and animals by keratinophilic fungi (dermatophytes) results in dermatophytosis (also known as tinea or ringworm). As conventional laboratory procedures for the identification of dermatophytes are either slow or lack specificity, improved diagnostic methods are required. The application of nucleic acid amplification technology has made rapid and precise identification of dermatophytes possible. Recent studies have shown that when one of the four random primers (OPAA11, OPD18, OPAA17 and OPU15) was used in arbitrarily primed PCR (AP-PCR), up to 20 of the 25 dermatophyte species or subspecies under investigation could be distinguished on the basis of characteristic band patterns detected in agarose gel electrophoresis. A combination of two random primers (OPD18 and OPAA17) used in separate reaction tubes identified 23 of the 25 dermatophyte species or subspecies examined. AP-PCR provides a rapid and practical tool for identification of dermatophyte isolates that is independent of morphological and biochemical characteristics and thus enhances laboratory diagnosis of dermatophytosis.
Importance of a 5′ Stem-Loop for Longevity of <i>papA</i> mRNA in <i>Escherichia coli</i> (1999)

High-level expression of the major pilus subunit (PapA) of uropathogenic strains of Escherichia coli results in part from the unusually long lifetime of the mRNA that encodes this protein. Here we report that the longevity of papA mRNA derives in large measure from the protection afforded by its 5' untranslated region. This papA RNA segment can prolong the lifetime of an otherwise short-lived mRNA to which it is fused. In vivo alkylation studies indicate that, in its natural milieu, the papA message begins with a stem-loop structure. This stem-loop is important for the stabilizing effect of the papA 5' untranslated region, as evidenced by the significant acceleration in papA mRNA decay that results from its removal.
Developments in the Application of Azoic Dyes in Printing (1953)

A brief review is made of the development of azoic dyes for printing, from the original application on β‐naphthol prepares, via the Rapid Fast and Rapidogen ranges, to the recently introduced neutral‐steaming dyes. The application of these new dyes in multicolour styles is discussed in some detail.
Letter (1993)

Dear Editor I am a staff nurse working in paediatric terminal care, currently undertaking a post-registration course in the care of the dying.
Knot detection in coarse resolution CT images of logs (2017)

The use of X-ray computed tomography (CT) scanning of logs in sawmill is becoming a reality in the last few years, usually with rather costly and complex machines resembling medical scanners. However, a scanning solution has been developed that is less costly and more robust, and therefore more suited for sawmill needs. The rather coarse data from this machine has not been fully evaluated regarding possibilities to detect internal features such as knots. In this study, a knot detection algorithm developed for medical scanners was applied to images from a coarse resolution scanner, from four different logs of various species, and with different image resolution. The objective was to see if it was possible to detect knots automatically in the images. If so, the aim was to calculate the knot detection rate and the accuracy of detected knot size and position. These numbers were calculated compared to manually measured reference knots. This resulted in a knot detection rate of about 53 % overall, and a well detected knot position, but poorly detected knot size. It is possible to observe a certain difference between species and reconstruction resolution, however the material is too small to draw any definite conclusions. As a preliminary study, it provides input for further investigation on knot detection in coarse resolution X-ray CT images. Future work involves scanning more logs to get more data, and to pinpoint the resolution needed for accurate knot detection using the current algorithm.
Performance Analysis of Frostless Heat Exchanger by Spreading Antifreeze Solution on Heat Exchanger Surface (2011)

The effect of antifreeze solution liquid film on the frost prevention is experimentally investigated. It is desirable that the antifreeze solution spreads widely on the heat exchanger surface forming thin liquid film to prevent frost nucleation while having small thermal resistance across the film. A porous layer coating technique is adopted to improve the wettability of the antifreeze solution on heat exchanger surface. The antifreeze solution spreads widely on the heat exchanger surface with 100 µm thickness by the capillary force resulted from the porous structure. It is observed that the antifreeze solution liquid film prevents a heat exchanger from frosting. The reductions of heat and mass transfer rate caused by the thin liquid film are only 1-2% compared with those for non-liquid film surface.
Cassava Plants with a Depleted Cyanogenic Glucoside Content in Leaves and Tubers. Distribution of Cyanogenic Glucosides, Their Site of Synthesis and Transport, and Blockage of the Biosynthesis by RNA Interference Technology (2005)

Transgenic cassava (Manihot esculenta Crantz, cv MCol22) plants with a 92% reduction in cyanogenic glucoside content in tubers and acyanogenic (<1% of wild type) leaves were obtained by RNA interference to block expression of CYP79D1 and CYP79D2, the two paralogous genes encoding the first committed enzymes in linamarin and lotaustralin synthesis. About 180 independent lines with acyanogenic (<1% of wild type) leaves were obtained. Only a few of these were depleted with respect to cyanogenic glucoside content in tubers. In agreement with this observation, girdling experiments demonstrated that cyanogenic glucosides are synthesized in the shoot apex and transported to the root, resulting in a negative concentration gradient basipetal in the plant with the concentration of cyanogenic glucosides being highest in the shoot apex and the petiole of the first unfolded leaf. Supply of nitrogen increased the cyanogenic glucoside concentration in the shoot apex. In situ polymerase chain reaction studies demonstrated that CYP79D1 and CYP79D2 were preferentially expressed in leaf mesophyll cells positioned adjacent to the epidermis. In young petioles, preferential expression was observed in the epidermis, in the two first cortex cell layers, and in the endodermis together with pericycle cells and specific parenchymatic cells around the laticifers. These data demonstrate that it is possible to drastically reduce the linamarin and lotaustralin content in cassava tubers by blockage of cyanogenic glucoside synthesis in leaves and petioles. The reduced flux to the roots of reduced nitrogen in the form of cyanogenic glucosides did not prevent tuber formation.
Fallopian tubal patency assessed by ultrasound following fluid injection. Work in progress. (1984)

The ability of ultrasound to detect patency of at least one fallopian tube by demonstrating free fluid in the cul-de-sac was evaluated in 35 infertile women. The results were compared with conventional hysterosalpingograms, which had been obtained simultaneously. Ultrasound demonstrated bilateral occlusion with a sensitivity of 100%, and showed tubal patency with a specificity of 96%. The ability to diagnose tubal occlusion or patency using this ultrasound technique, which the authors have designated "sonosalpingography," eliminates unnecessary exposure of the female pelvis to ionizing radiation and avoids the use of iodinated contrast material.
Production Method Affects the Pharmacokinetic and Ex Vivo Biological Properties of Low Molecular Weight Heparins (1997)

Low molecular weight (LMW) heparins have prolonged circulating half-lives relative to unfractionated heparin, but the rates of plasma clearance differ between different LMW preparations. To determine the impact of method of production on their pharmacokinetic and ex vivo biological properties, two LMW heparins of similar molecular weight distribution, Logiparin and Fragmin, were radiolabelled with 125I, administered intravenously with 4 mg/kg of carrier drug into rabbits, and the circulating radiolabelled material and anti-Xa activity were analysed by size exclusion chromatography and affinity for antithrombin and Polybrene. Following administration of Logiparin, the anti-Xa amidolytic activity was eliminated with the same half-life as the anti-thrombin-binding radiolabel and was not neutralised by antibody against tissue factor pathway inhibitor (TFPI). Larger molecules were cleared preferentially and were no longer detectable 8 h post injection. These findings resemble those we have previously described for Enoxaparin. After Fragmin administration the antithrombin binding radiolabel was cleared more rapidly than the anti-Xa activity, and at late times after injection a significant amount of this activity was neutralised by antibody against TFPI. Sulphated radiolabel was eliminated with a similar half-life to the anti-Xa activity and sulphated molecules > 6000 Da remained in the circulation 8 h after administration. Fragmin, unlike Logiparin and Enoxaparin, has no negatively charged sulphamino group at the reducing end of the molecule. We suggest that this minimises cellular interaction and protects the larger molecules from elimination. They remain in the circulation, contributing to anti-Xa activity by binding TFPI. Thus the method of production of LMW heparins may significantly influence their pharmacokinetic properties and circulating anticoagulant activities.
An efficient approach for solving a class of nonlinear 2D parabolic PDEs (2004)

We consider a class of nonlinear 2D parabolic equations that allow for an efficient application of an operator splitting technique and a suitable linearization of the discretized problem. We apply our scheme to study the finite extinction phenomenon for the porous‐medium equation with strong absorption. A comparison of accuracy and computational efficiency of the resulting algorithms for several test problems is presented.
Mode of Delivery – Effects on Gut Microbiota and Humoral Immunity (2007)

Our findings demonstrate that the mode of delivery may have, possibly via gut microbiota development, significant effects on immunological functions in the infant (http://www.clinicaltrials.gov/ct/gui/show/NCT00167700).
Short-Rerm Mortality Predictions for Critically Ill Hospitalized Adults: Science and Ethics (1991)

Modern life-sustaining therapy often succeeds in postponing death but may be ineffective at restoring health. Decisions that influence the time and circumstances of an individual's death are now common and require an accurate and comprehensive characterization of likely outcome. Evaluation of alternative outcomes requires acknowledgement that most patients find some outcomes to be worse than death. Improved understanding of major predictors of patient outcome, combined with rapidly expanding technical abilities to collect and manipulate large amounts of detailed clinical data, have created a new intellectual and technical basis for estimating outcomes from intensive medical care. Such objective probability estimates, such as the system described here, can reduce uncertainty about difficult clinical decisions and can be used by physicians, patients, and society to reorient health care toward more scientifically and ethically defensible approaches.
The stability of water in the pores of acid etched human enamel (1978)

A mechanism is proposed, explaining the fact that drying by compressed air for 5-10 sec. will remove acid and dissolved enamel from the relatively long and narrow pores of etched enamel surfaces. It is a consequence of the proposed mechanism that water in the liquid state is not stable in the pores, and accordingly, that condensation of water vapour on the etched and dried surfaces is not likely to occur. This was confirmed by studying tag formation in etched enamel surfaces under conditions where water vapour will condense on unetched tooth surfaces.
Behavior of tertiary phosphine and arsine complexes of copper(I) in chloroform solution (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBehavior of tertiary phosphine and arsine complexes of copper(I) in chloroform solutionStephen J. Lippard and James J. MayerleCite this: Inorg. Chem. 1972, 11, 4, 753–759Publication Date (Print):April 1, 1972Publication History Published online1 May 2002Published inissue 1 April 1972https://pubs.acs.org/doi/10.1021/ic50110a019https://doi.org/10.1021/ic50110a019research-articleACS PublicationsRequest reuse permissionsArticle Views371Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Round Table: Oncology and Sexuality: L14: Erectile Dysfunction After Radiotherapy for Prostate Cancer (2004)

The goal of this work was to characterize the blood flow in cavernosal–spongiosal communications (CSCs) in patients with erectile dysfunction using color Doppler ultrasound. Peak systolic velocity was measured in the CSCs, cavernosal artery and urethral artery in 72 erectile dysfunction patients of the Han ethnic group in southern China. Blood in the CSCs was observed to flow from the cavernosal artery to the urethral artery in all except 5 patients with arteriogenic insufficiency whose blood flow was bidirectional. Peak systolic velocity in erectile dysfunction patients with normal vascular function or veno-occlusive dysfunction was significantly lower in the CSCs than in the cavernosal artery (p < 0.01), but significantly higher than in the urethral artery (p < 0.05). Peak systolic velocities in CSCs in patients with arteriogenic insufficiency were significantly lower than those in the cavernosal (p < 0.01) and urethral (p < 0.01) arteries. The direction of blood flow in the CSCs is determined by the pressure gradient between the cavernosal and urethral arteries.
Evaluation of a fully automated end-tidal carbon monoxide instrument for breath analysis. (1996)

We evaluated a novel, portable breath sampler/CO-quantifying instrument [Baby's Breath Carbon Monoxide Analyzer (BB); Natus Medical], developed for use at the bedside or with gas samples collected into bags. Bench tests demonstrated that the CO measurements were linear, accurate, and precise when compared with gas chromatography (GC) results. In vivo tests (n = 30) performed with adults showed excellent correlation between end-tidal breath CO measurements (ETCO) corrected for inhaled CO (ETCOc) as determined by BB and GC. Breath sampling efficiency was 96%. ETCOc measurements and blood carboxyhemoglobin fractions (% of total hemoglobin) corrected for inhaled CO (COHbc) correlated strongly: COHbc = 0.25 ETCOc--0.01 microL/L CO (r2 = 0.97, Sy/x = 0.47, SE slope = 0.01, n = 30). The imprecision, assessed by the mean of the population's CV for triplicate determinations, was 11%. Measurements with healthy and hemolytic term newborns showed that ETCOc values of > 3 microL/L correlated with known hemolytic conditions. We conclude that this instrument is clinically reliable and can be used to noninvasively measure ETCO in neonates and adults.
Rheological Properties of Chemically Modified Wood: Relationship Between Dimensional and Creep Stability (1992)

A typology of chemical modifications of wood based on the interaction of water with the molecular constituents of the lignocellulosic material is proposed. The model accounts for both the moisture expansion and the so-called mechanosorptive creep induced by moisture changes under load. Anti-creep efficiency (ACE) values were obtained for wood specimens modified with fourteen different types of chemical treatments and subjected to a 4-day creep-recovery test under cyclic humidity conditions. The relationship between dimensional stability, as measured by anti-swelling efficiency (ASE), and ACE was determined for the different treatments. Treatments such as polyethylene glycol impregnation or etherification with epoxides, in which the hydrophilic nature of the bulking agent is not counter-balanced by crosslinking, yielded high ASE values but increased mechanosorptive creep instead of reducing it.
DragonFly: a versatile UAV platform for the advancement of aircraft navigation and control (2002)

The DragonFly experimental test bed is a platform that supports new research and innovations in navigation, fault tolerant control and multiple vehicle coordination. It consists of two UAVs with modular onboard avionics packages, which communicate through a wired and wireless network to the ground and lab development systems running QNX real-time OS. Its modularity and networked architecture is key in supporting such a wide range of concurrent research. This paper gives an overview of the DragonFly experimental test bed and the specific research goals that it currently supports.