gebhart/patrepeval huggingface dataset:
A saúde mental dos estudantes de medicina da Universidade da Beira Interior (2009)

O principal objectivo deste estudo foi investigar as relações entre os níveis de saúde mental dos estudantes de medicina da Universidade da Beira Interior, nas suas vertentes positivas e negativas (bem-estar e distress psicológico respectivamente) e factores sócio-demográficos, anos de curso, consumo de substâncias psicoactivas e acompanhamento psicológico por profissional de saúde. Este estudo transversal consistiu na aplicação online de um questionário anónimo, construído para o efeito, que esteve disponível entre Fevereiro e Março de 2009, constituído por quatro secções: a) Dados sócio-demográficos b) Inventário de Saúde Mental de Ribeiro (MHI) c) Consumo de substâncias psicoactivas no último mês e d) Apoio psicológico. Os resultados foram analisados no programa estatístico SPSS versão 17 para Windows e consideraram-se os resultados significativos para p <0,05. No total, 272 (49,3%) estudantes responderam ao inquérito, 215 do sexo feminino. O ciclo básico de formação apresentou níveis significativamente inferiores na escala de bem-estar psicológico. O sexo feminino, o 3º ano de formação e o consumo de tranquilizantes/sedativos no último mês revelaram uma influência negativa, estatisticamente significativa, em ambas as vertentes de saúde mental avaliadas. Não houve relação estatística entre os níveis de saúde mental e o consumo de outras substâncias psicoactivas. Constatou-se que, dos estudantes com níveis de saúde mental abaixo da média, 8,6% é seguido por profissionais de saúde e 10% realiza terapêutica farmacológica a longo prazo para sintomas relacionados com a saúde mental. Cerca de 10% dos estudantes já realizou terapêutica farmacológica sem prescrição médica para sintomas relacionados com a saúde mental e estes apresentam níveis significativamente inferiores de saúde mental. A ideação suicida no último mês foi reportada por 10% dos estudantes. Este estudo aponta para a necessidade de se compreender as causas e as consequências dos piores níveis de saúde mental no ciclo básico de formação, predominantemente no 1º e 3º ano, assim como nos estudantes do sexo feminino. É necessário promover estratégias que promovam o bem-estar psicológico durante a formação médica, ensinem os estudantes a entender e a lidar com sintomas de distress e ajudá-los a reconhecer quando necessitam de ajuda, disponibilizando-a.
Pyridazines in Crystal Engineering. A Systematic Evaluation of the Role of Isomerism and Steric Factors in Determining Crystal Packing and Nano/Microcrystal Morphologies (2010)

The present study focuses on understanding hydrogen bond patterns in a series of variably substituted pyridyl-pyridazines as a function of positional isomerism and steric factors. A relatively uncommon multiple hydrogen bond acceptor nature of pyridazine has been observed in the di- and tripyridazine compounds. With increasing aromatic substitution and thereby steric hindrance, a systematic transition has been observed from close-packed to porous solvated assemblies. Distinct morphologies of the organic nano/microparticles, obtained by the precipitation method, indicate that the molecules interact with the solvent system in different ways.
Novel On-wafer Radiation Pattern Measurement Technique for MEMS Actuator Based Reconfigurable Patch Antennas (2002)

The paper presents a novel on-wafer, antenna far field pattern measurement technique for microelectromechanical systems (MEMS) based reconfigurable patch antennas. The measurement technique significantly reduces the time and the cost associated with the characterization of printed antennas, fabricated on a semiconductor wafer or dielectric substrate. To measure the radiation patterns, the RF probe station is modified to accommodate an open-ended rectangular waveguide as the rotating linearly polarized sampling antenna. The open-ended waveguide is attached through a coaxial rotary joint to a Plexiglas(Trademark) arm and is driven along an arc by a stepper motor. Thus, the spinning open-ended waveguide can sample the relative field intensity of the patch as a function of the angle from bore sight. The experimental results include the measured linearly polarized and circularly polarized radiation patterns for MEMS-based frequency reconfigurable rectangular and polarization reconfigurable nearly square patch antennas, respectively.
Hybrid Shipping Architectures: A Survey (2001)

Recent advances in relational database systems include distributed systems that can choose to execute portions of query processing functionality at server or client sites. A symmetric problem that has received little attention is the partitioning of client application functionality between client and server. This report presents a survey of the literature related to both of these partitioning problems.
ASSESSMENT OF<i>BACILLUS LICHENIFORMIS</i>α-AMYLASE AS A CANDIDATE ENZYME FOR GENETIC ENGINEERING OF MALTING BARLEY<sup>1</sup> (1996)

Bacillus licheniformis α-amylase, a thermostable starch-degrading enzyme, has been assessed as a candidate enzyme for the genetic transformation of malting barley. The temperature optimum, pH optimum and thermostability of B. licheniformis α-amylase were compared with those of barley α-amylase. The bacterial enzyme has a higher pH optimum (−9), a higher temperature optimum (−90°C) and much higher thermostability at elevated temperatures than the barley enzyme. The specific activity of the bacterial enzyme under conditions of pH and temperature relevant to the brewing process (pH 5.5, 65°C) is −1.5-fold higher than that of the barley enzyme. Measurements of α-amylase activity during a micro-mash showed that the bacterial enzyme is at least as stable as the barley enzyme under these conditions, and that a level of expression for the bacterial enzyme corresponding to −0.5% of total malt protein would approximately double the α-amylase activity in the mash. B. licheniformis α-amylase activity was rapidly eliminated by boiling following mashing as would occur during brewing. The combined results suggest that barley expressing the bacterial enzyme may be useful in the brewing process.
Homogeneous Catalysis. II. The Mechanism of the Hydrosilation of Olefins Catalyzed by Group VIII Metal Complexes<sup>1</sup> (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHomogeneous Catalysis. II. The Mechanism of the Hydrosilation of Olefins Catalyzed by Group VIII Metal Complexes1A. J. Chalk and J. F. HarrodCite this: J. Am. Chem. Soc. 1965, 87, 1, 16–21Publication Date (Print):January 1, 1965Publication History Published online1 May 2002Published inissue 1 January 1965https://pubs.acs.org/doi/10.1021/ja01079a004https://doi.org/10.1021/ja01079a004research-articleACS PublicationsRequest reuse permissionsArticle Views5569Altmetric-Citations760LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Portable desktop applications based on P2P transportation and virtualization (2008)

Play-on-demand is usually regarded as a feasible access mode for web content (including video, web pages and so on), web services and some Software-As-A-Service (SaaS) applications, but not for common desktop applications. This paper presents such a solution for Windows desktop-applications based on lightweight virtualization and network transportation technologies which allows a user to run her personalized software on any compatible computer across the Internet even though they do not exist on local disks of the host.

In our approach, the user's data and their configurations are stored on a portable USB device. At run time, the desktop applications are downloaded from the Internet and run in a lightweight virtualization environment in which some resource-accessing APIs, such as registry, files/ directories, environment variables, and the like, are intercepted and redirected to the portable device or network as needed. Because applications are played without installation, like media, they can be called streaming software. Moreover, to protect software vendors' rights, access control technologies are used to block any illegal access. In the current implementation, P2P transportation is used as the transport method. However, our design actually does not rely on P2P, and another data delivery mechanism, like a dedicated file server, could be employed instead to make the system more predictable.

This paper describes the design and technical details for this system, presents a demo application and evaluates it performance. The proposed solution is shown to be more efficient in performance and storage capacity than some of the existing solutions based on VM techniques.
Guide to integrating forensic techniques into incident response (2006)

The Information Technology Laboratory (ITL) at the National Institute of Standards and Technology (NIST) promotes the U.S. economy and public welfare by providing technical leadership for the nation's measurement and standards infrastructure. ITL develops tests, test methods, reference data, proof of concept implementations, and technical analysis to advance the development and productive use of information technology. ITL's responsibilities include the development of technical, physical, administrative, and management standards and guidelines for the cost-effective security and privacy of sensitive unclassified information in Federal computer systems. This Special Publication 800-series reports on ITL's research, guidance, and outreach efforts in computer security and its collaborative activities with industry, government, and academic organizations.
Hg-Sensitized Photochemical Vapor Deposition Application to Hydrogenated Amorphous Silicon Photoconversion Layer Overlaid on Charge Coupled Device (1995)

An Hg-sensitized photochemical vapor deposition method has been developed which has enabled a hydrogenated amorphous silicon photoconversion layer to be overlaid on a charge coupled device (CCD) imager, without a pixel separation structure. This chemical vapor deposition (CVD) method has been used to realize imaging devices with high sensitivity and high resolution for high-definition TV.
Properties of PVDF Polymer for Sonar (1985)

Polyvinylidene fluoride (PVDF) polymer is evaluated for application in large sonar arrays. The piezoelectric coefficients and elastic constants of thick (550 urn) PVDF produced at Raytheon are measured, and the apparatus for making the measurements is described. It is shown, both theoretically and experimentally, that electrodes deposited on the surface can stiffen the polymer and significantly alter the observed properties. The free-f ield frequency response for an experimental hydrophone is shown over a broad frequency range, f ee of spurious resonances. Stability to relatively high temperature (90°C) and to high static pressure (6.9 MPa = 1000 ps 1 are shown from experimental data.
Wound closure and wound management (2010)

Wound closure and infection control are the primary goal of wound management. A variety of disinfectants and antimicrobial agents are widely available today and routinely achieve infection control. On the contrary, wound closure still remains a challenging goal. Cell adhesion, migration and contraction play significant roles in creating contractile force of patent wound margins and in contributing to wound closure. Modulations of these cellular behaviors have been investigated in the context of wound contraction; however, therapeutic strategy to achieve wound closure has not been established. Recently, we have reported that a previously unknown cytoskeleton molecule, wound inducible transcript-3.0 (wit3.0) also known as fibroblast growth factor receptor 1 oncogene partner 2 (FGFR1OP2), can significantly modulate fibroblast-driven wound closure in vitro and in vivo. The dynamic role of cytoskeleton in different experimental models may provide a novel platform for designing the therapeutic target of wound management.
Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration (2013)

Gaucher disease has recently received wide attention due to the unexpected discovery that it is a genetic risk factor for Parkinson's disease. Gaucher disease is caused by the defective activity of the lysosomal enzyme, glucocerebrosidase (GCase; GBA1), resulting in intracellular accumulation of the glycosphingolipids, glucosylceramide and psychosine. The rare neuronopathic forms of GD (nGD) are characterized by profound neurological impairment and neuronal cell death. We have previously described the progression of neuropathological changes in a mouse model of nGD. We now examine the relationship between glycosphingolipid accumulation and initiation of pathology at two pre-symptomatic stages of the disease in four different brain areas which display differential degrees of susceptibility to GCase deficiency. Liquid chromatography electrospray ionization tandem mass spectrometry demonstrated glucosylceramide and psychosine accumulation in nGD brains prior to the appearance of neuroinflammation, although only glucosylceramide accumulation correlated with neuroinflammation and neuron loss. Levels of other sphingolipids, including the pro-apoptotic lipid, ceramide, were mostly unaltered. Transmission electron microscopy revealed that glucosylceramide accumulation occurs in neurons, mostly in the form of membrane-delimited pseudo-tubules located near the nucleus. Highly disrupted glucosylceramide-storing cells, which are likely degenerating neurons containing massive inclusions, numerous autophagosomes and unique ultrastructural features, were also observed. Together, our results indicate that a certain level of neuronal glucosylceramide storage is required to trigger neuropathological changes in affected brain areas, while other brain areas containing similar glucosylceramide levels are unaltered, presumably because of intrinsic differences in neuronal properties, or in the neuronal environment, between various brain regions.
Polymerization of 1-(trimethylsilyl)-1-propyne by halides of niobium(V) and tantalum(V) and polymer properties (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolymerization of 1-(trimethylsilyl)-1-propyne by halides of niobium(V) and tantalum(V) and polymer propertiesToshio Masuda, Eiji Isobe, and Toshinobu HigashimuraCite this: Macromolecules 1985, 18, 5, 841–845Publication Date (Print):May 1, 1985Publication History Published online1 May 2002Published inissue 1 May 1985https://pubs.acs.org/doi/10.1021/ma00147a003https://doi.org/10.1021/ma00147a003research-articleACS PublicationsRequest reuse permissionsArticle Views448Altmetric-Citations157LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<sup>1</sup>H NMR studies of echistatin in solution (1991)

Two-dimensional 1H-NMR methods have been used to obtain complete proton resonance assignments for the 49-residue protein echistatin from the viper Echis carinatus. The protein in solution contains only a small amount of regular secondary structure with four very short beta-strands. These beta-strands form two short segments of antiparallel beta-sheet, as evidenced by the observed cross-strand NOE. The first two strands are connected with a tight reverse turn, whereas the remaining two strands are linked together by an 11-residue loop forming a so-called hairpin. The tripeptide unit Arg-Gly-Asp, responsible for the binding of echistatin to the fibrinogen receptor glycoprotein GPIIb/IIIa, is located at the tip of this very hydrophilic loop.
IC RELIABILITY SIMULATION (Invited Paper) (1991)

The motivation, challenges and status of IC reliability simulation are discussed. Reliability simulator BERT is used to illustrate the physical models and approaches used to simulate the hot electron effect, oxide time-dependent breakdown, electromigration, and bipolar transistor gain degradation.
Tracking and summarizing news on a daily basis with Columbia's Newsblaster (2002)

Recently, there have been significant advances in several areas of language technology, including clustering, text categorization, and summarization. However, efforts to combine technology from these areas in a practical system for information access have been limited. In this paper, we present Columbia's Newsblaster system for online news summarization. Many of the tools developed at Columbia over the years are combined together to produce a system that crawls the web for news articles, clusters them on specific topics and produces multidocument summaries for each cluster.
Analysis of DNA sequences which regulate the transcription of a herpes simplex virus immediate early gene (1984)

The locations and functions of DNA sequences involved in transcription of the gene encoding herpes simplex virus type 1 immediate early (IE) mRNAs 4 and 5 were analyzed by use of a transient-expression assay. The region upstream of the genes encoding IE mRNAs 4 and 5 was fused to the thymidine kinase gene coding sequences, and production of enzyme or RNA was measured after transfection of plasmids into BHK cells. The effect of deletions in the upstream region was determined in the absence or presence of a virus structural component which stimulates herpes simplex virus IE transcription. Two distinct units were identified. One of these was a promoter which required not more than 69 base pairs of DNA specific for the genes encoding IE mRNAs 4 and 5 upstream from the mRNA 5' terminus. The other was a far-upstream region which mediated the response to the virion component and had an upstream boundary between nucleotides -347 and -335. An origin of DNA replication was interposed between these two units. The element TAATGAGATAC , which represents a consensus sequence present in the upstream regions of all herpes simplex type 1 IE genes, appeared to be essential for stimulation by the virion component. The activity of this element was modulated by the sequences which flank it, especially by regions having extremely high contents of guanine plus cytosine and which contain a conserved unit CCCGCCC or its complement GGGCGGG .
Fault-Tolerant Postselected Quantum Computation: Threshold Analysis (2004)

The schemes for fault-tolerant postselected quantum computation given in [Knill, Fault-Tolerant Postselected Quantum Computation: Schemes, http://arxiv.org/abs/quant-ph/0402171] are analyzed to determine their error-tolerance. The analysis is based on computer-assisted heuristics. It indicates that if classical and quantum communication delays are negligible, then scalable qubit-based quantum computation is possible with errors above 1% per elementary quantum gate.
Characterization of Simian Immunodeficiency Virus SIV <sub>SM</sub> /Human Immunodeficiency Virus Type 2 Vpx Function in Human Myeloid Cells (2008)

Human immunodeficiency virus type 2 (HIV-2)/simian immunodeficiency virus SIV(SM) Vpx is incorporated into virion particles and is thus present during the early steps of infection, when it has been reported to influence the nuclear import of viral DNA. We recently reported that Vpx promoted the accumulation of full-length viral DNA following the infection of human monocyte-derived dendritic cells (DCs). This positive effect was exerted following the infection of DCs with cognate viruses and with retroviruses as divergent as HIV-1, feline immunodeficiency virus, and even murine leukemia virus, leading us to suggest that Vpx counteracted an antiviral restriction present in DCs. Here, we show that Vpx is required, albeit to a different extent, for the infection of all myeloid but not of lymphoid cells, including monocytes, macrophages, and monocytoid THP-1 cells that had been induced to differentiate with phorbol esters. The intracellular localization of Vpx was highly heterogeneous and cell type dependent, since Vpx localized differently in HeLa cells and DCs. Despite these differences, no clear correlation between the functionality of Vpx and its intracellular localization could be drawn. As a first insight into its function, we determined that SIV(SM)/HIV-2 and SIV(RCM) Vpx proteins interact with the DCAF1 adaptor of the Cul4-based E3 ubiquitin ligase complex recently described to associate with HIV-1 Vpr and HIV-2 Vpx. However, the functionality of Vpx proteins in the infection of DCs did not strictly correlate with DCAF1 binding, and knockdown experiments failed to reveal a functional role for this association in differentiated THP-1 cells. Lastly, when transferred in the context of a replication-competent viral clone, Vpx was required for replication in DCs.
Vital Sign Monitoring Through the Back Using an UWB Impulse Radar With Body Coupled Antennas (2018)

Radar devices can be used in nonintrusive situations to monitor vital sign, through clothes or behind walls. By detecting and extracting body motion linked to physiological activity, accurate simultaneous estimations of both heart rate (HR) and respiration rate (RR) is possible. However, most research to date has focused on front monitoring of superficial motion of the chest. In this paper, body penetration of electromagnetic (EM) wave is investigated to perform back monitoring of human subjects. Using body-coupled antennas and an ultra-wideband (UWB) pulsed radar, in-body monitoring of lungs and heart motion was achieved. An optimised location of measurement in the back of a subject is presented, to enhance signal-to-noise ratio and limit attenuation of reflected radar signals. Phase-based detection techniques are then investigated for back measurements of vital sign, in conjunction with frequency estimation methods that reduce the impact of parasite signals. Finally, an algorithm combining these techniques is presented to allow robust and real-time estimation of both HR and RR. Static and dynamic tests were conducted, and demonstrated the possibility of using this sensor in future health monitoring systems, especially in the form of a smart car seat for driver monitoring.