gebhart/patrepeval huggingface dataset:
High speed migration of multidimensional seismic data (1991)

The authors introduce the seismic imaging problem and formulate several algorithms suitable for concurrent VLSI implementation. They introduce an optimal VLSI architecture for 2-D and 3-D frequency-domain migration and propose a new method of matrix transposition for the 2-D parallel phase shift migration algorithm. They also propose a systolic array architecture for computation of a time-domain finite-difference migration algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Conditional Inactivation of<i>Pten</i>with<i>EGFR</i>Overexpression in Schwann Cells Models Sporadic MPNST (2012)

The genetic mechanisms involved in the transformation from a benign neurofibroma to a malignant sarcoma in patients with neurofibromatosis-type-1- (NF1-)associated or sporadic malignant peripheral nerve sheath tumors (MPNSTs) remain unclear. It is hypothesized that many genetic changes are involved in transformation. Recently, it has been shown that both phosphatase and tensin homolog (PTEN) and epidermal growth factor receptor (EGFR) play important roles in the initiation of peripheral nerve sheath tumors (PNSTs). In human MPNSTs, PTEN expression is often reduced, while EGFR expression is often induced. We tested if these two genes cooperate in the evolution of PNSTs. Transgenic mice were generated carrying conditional floxed alleles of Pten, and EGFR was expressed under the control of the 2',3'-cyclic nucleotide 3'phosphodiesterase (Cnp) promoter and a desert hedgehog (Dhh) regulatory element driving Cre recombinase transgenic mice (Dhh-Cre). Complete loss of Pten and EGFR overexpression in Schwann cells led to the development of high-grade PNSTs. In vitro experiments using immortalized human Schwann cells demonstrated that loss of PTEN and overexpression of EGFR cooperate to increase cellular proliferation and anchorage-independent colony formation. This mouse model can rapidly recapitulate PNST onset and progression to high-grade PNSTs, as seen in sporadic MPNST patients.
Damage to the Peritoneal Membrane by Glucose Degradation Products Is Mediated by the Receptor for Advanced Glycation End-Products (2005)

Peritoneal dialysis is limited by morphologic changes of the peritoneal membrane. Use of peritoneal dialysis fluids (PDF) that contain glucose degradation products (GDP) generates advanced glycation end-products (AGE) within the peritoneal cavity. It is unknown whether peritoneal damage is causally related to AGE-receptor for AGE (RAGE) interaction. The effects of PDF were compared with different amounts of GDP on morphologic changes of the peritoneal membrane in 48 wild-type (WT) and 48 RAGE-deficient mice. PDF (1 ml) were instilled twice daily over a period of 12 wk. Groups with eight animals each received no manipulation (sham); sham instillation (sham i.p.); or filter-sterilized, glucose-free, conventional low GDP- or high GDP PDF. In vitro (generation of AGE fluorescence in PDF) and in vivo (immunohistochemistry for carboxymethyllysine), a GDP-dependent increase of AGE formation occurred. Inflammation and neoangiogenesis were augmented in WT mice that were treated with high GDP accompanied by upregulation of CD3+ T cells, increased NF-kappaB binding activity, increased lectin, and vascular endothelial growth factor expression. Furthermore, pronounced submesothelial fibrosis was found with increased expression of TGF-beta1. Exposure to low GDP resulted in only mild inflammation and neoangiogenesis (compared with sham i.p.) and no fibrosis in WT mice. The findings in WT contrasted with those in RAGE-deficient mice, which showed no increased inflammation (CD3+ T cells and NF-kappaB binding activity), neoangiogenesis (by lectin and vascular endothelial growth factor expression), or fibrosis (expression of TGF-beta1) after long-term exposure to GDP-containing PDF. Peritoneal damage by GDP in PDF is dependent at least in part on AGE-RAGE interaction.
Trimipramine in rheumatoid arthritis: a randomized double-blind trial in relieving pain and joint tenderness (1986)

The effect of low-dose trimipramine (25 to 75 mg/day) on joint pain and tenderness in 36 patients with rheumatoid arthritis was studied in a randomized double-blind trial carried out over a period of 12 weeks. The patients were pre-selected to include only patients who were depressed on a 'self-rating depression scale' but had no evidence of fibrositic 'trigger-points'. The results showed that joint pain and tenderness were significantly reduced with trimipramine, but depression scores remained unchanged.
Stacking migrated shot profiles by image processing (1989)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1989Stacking migrated shot profiles by image processingAuthors: Patricia BoronadNaamen KeskesMarc VerpratPatricia BoronadC.I.S.I, Naamen KeskesELF Aquitaine, France, and Marc VerpratELF Aquitaine, Francehttps://doi.org/10.1190/1.1889520 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1889520FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1989ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1989 Pages: 1375 publication data© 1989 Copyright © 1989 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 10 Feb 2005 CITATION INFORMATION Patricia Boronad, Naamen Keskes, and Marc Verprat, (1989), "Stacking migrated shot profiles by image processing," SEG Technical Program Expanded Abstracts : 1253-1257. https://doi.org/10.1190/1.1889520 Plain-Language Summary PDF DownloadLoading ...
Physico-chemical and functional properties of rye nonstarch polysaccharides. I. Colorimetric analysis of pentosans and their relative monosaccharide compositions in fractionated (milled) rye products (1989)

Cereal Chem. 66(2):107-1 11 The water-soluble, enzyme-extractable, and total pentosans (WSP, EEP, in the bran, whereas the shorts contained the highest proportion of both the and TP, respectively) of rye kernels were estimated by a modification of the WSP and the EEP. The proportion of WSP and EEP relative to the TP orcinol-hydrochloric acid method of Hashimoto et al (1987a). varied widely. D-(+)-Xylose and L-(+)-arabinose were the most abundant Modifications included absorbance readings both at 670 and 580 nm to monosaccharides, along with significant amounts of D-(+)-glucose. D-(+)minimize the small but significant interference by hexose sugars in the Galactose, and D-(+)-mannose were present in trace amounts. The WSP in analytical figures and appropriate dilution of the pentosan extracts before different milling fractions had smaller variations in the arabinose/ xylose analysis, as rye contains more pentosans than wheat. The relative ratios (0.76-0.81) than was observed for the EEP (0.58-0.80) and TP monosaccharide ratios in the different milling extracts were estimated by (0.74-1.09). The EEP and TP were relatively richer in xylose for the bran gas chromatography of the alditol acetates of the monosaccharides released and the short fractions as opposed to what was found for the fine flour upon hydrolysis of the pentosan extracts. The highest proportion of TP was fractions.
The crystallins: genes, proteins and diseases. (1997)

The crystallins were discovered as the structural proteins of the vertebrate eye lens in the last century by C.T. Mörner (Z. Physiol. Chem. 18, 1893, 61-106). Since that time the mammalian crystallins referred to as alpha-, beta-, and gamma-crystallins have been characterized with respect to their genetic organization, the regulation of their expression pattern and their participation in several diseases. Moreover, some crystallins have also been discovered outside the eye. Evolutionary analysis has demonstrated the relationship of crystallins to proteins involved in protection against stress. The alpha-crystallins are considered to be molecular chaperones and members of the small heat shock protein family; they have autokinase activity and are involved in the gamma-crystallin gene activation. The alpha-crystallins are associated with a broad variety of neurological disorders. The beta/gamma-crystallin superfamily is characterized by four greek key motifs. The various N- and C-terminal extensions of the beta/gamma-crystallins are mainly responsible for their distinct biophysical and biochemical properties. Modifications in the beta/gamma-crystallins or mutations in their genes lead to opacification of the eye lens (cataract). Other proteins found to be expressed at relatively high levels in the lens are characterized bytheir strong relationship to well-known enzymes. They are referred to as enzyme-crystallins, and as one example, the xi-crystallin will be discussed. It has evolved from a quinone oxidoreductase using a lens-specific promoter, and a mutation in xi-crystallin is involved in cataract formation.
[The factors in decreased blood flow in the carotid arteries]. (1994)

The circulation volume (CV) in the carotid arteries (CA) has been studied at ultrasonic duplex scanning in 219 patients with a history of acute cerebral circulation disturbance (ACCD), 26 patients with vascular dementia (VD) and in 54 healthy controls. Reduced CV in CA was registered both in ACCD and VD patients who had or were of CA stenosis. More severe fall of CV in CA for VD patients was not associated with increasing occlusion of CA. In the absence of obvious cardiac affection (fibrillation, myocardial infarction) in ACCD and VD patients echocardiography recorded insignificant reduction of myocardial contractility and cardiac output. The majority of these patients without cardiac disease or CA stenosis had arterial hypertension which is supposed to be an essential factor of CV lowering in CA.
Mediation by a CREB Family Transcription Factor of NGF-Dependent Survival of Sympathetic Neurons (1999)

Nerve growth factor (NGF) and other neurotrophins support survival of neurons through processes that are incompletely understood. The transcription factor CREB is a critical mediator of NGF-dependent gene expression, but whether CREB family transcription factors regulate expression of genes that contribute to NGF-dependent survival of sympathetic neurons is unknown. CREB-mediated gene expression was both necessary for NGF-dependent survival and sufficient on its own to promote survival of sympathetic neurons. Moreover, expression of Bcl-2 was activated by NGF and other neurotrophins by a CREB-dependent transcriptional mechanism. Overexpression of Bcl-2 reduced the death-promoting effects of CREB inhibition. Together, these data support a model in which neurotrophins promote survival of neurons, in part through a mechanism involving CREB family transcription factor-dependent expression of genes encoding prosurvival factors.
A dual‐band planar inverted‐F patch antenna with a branch‐line slit (2002)

Abstract By embedding a branch‐line slit in the radiating patch of a planar inverted‐F patch antenna, novel 900 and 1800 MHz dual‐band operation is obtained. The embedded branch‐line slit has two branch slits (one long folded slit and one short bent slit) protruding from the main slit which has an open end at the patch boundary. The main slit and the long folded branch slit together strongly meander the excited patch surface currents starting from the feed to the portion of the patch encircled by the folded branch slit, which leads to a significant reduction in the required dimensions for the proposed antenna. In addition, the two operating frequencies have wavelengths corresponding to about 4.0 and 2.0 times the length of the above‐mentioned meandered patch surface current path. The short bent branch slit, on the other hand, mainly serves as a tuning slit for achieving good impedance matching of the two operating frequencies. The proposed antenna and experimental results are described in detail in this paper. © 2002 John Wiley & Sons, Inc. Microwave Opt Technol Lett 32: 310–312, 2002.
Synthese laxativ wirksamer meso‐substituierter Hydroxyanthrone, 3. Mitt. Michael‐Addition mit 1,8‐Dihydroxyanthron‐(9) (1977)

Abstract Michael ‐Additionen mit 1,8‐Dihydroxyanthron‐(9) ( 1 ) und Acrolein, Acrylsäurederivaten und 2‐bzw. 4‐Vinylpyridin werden beschrieben.
Vagal Nerve Stimulation in Chronic Heart Failure: An Antiinflammatory Intervention? (2004)

Li et al 1 recently reported that vagal nerve stimulation improved survival in otherwise untreated rats with heart failure secondary to left coronary artery ligation. Although this finding is indeed intriguing and of potential therapeutic importance, the authors are understandably speculative about the possible mechanisms underlying this observation.
SiC Growth by Laser CVD and Process Analysis (2006)

The goal of this research is to investigate how to deposit SiC material from methyltrichlorosilane (MTS) and H2 using the LCVD technique. Two geometries were targeted, fiber and line. In order to eliminate the volcano effect for LCVD-SiC deposition, a thermodynamics model was developed to check the feasibility and determine the deposition temperature ranges that will not cause the volcano effect, theoretically. With the aid of the thermodynamic calculations and further experimental explorations, the processing conditions for SiC fibers and lines without volcano effect were determined. The experimental relationships between the volcano effect and the deposition temperatures were achieved. As for the SiC lines, the deposition conditions for eliminating volcano effect were determined with the help of surface response experiment and the experience of SiC fiber depositions. The LCVD process of SiC deposition was characterized by performing a kinetic study of SiC deposition. The deposits were characterized by the means of polishing, chemical etching, and SEM technique. A coupled thermal and structural model was created to calculate the thermal residual stress present in the deposits during the deposition process and during the cooling process. Laser heating of LCVD system was studied by developing another model. The transient temperature distribution within the fiber and substrate was obtained. The theoretical relationships between the laser power and the fiber heights for maintaining constant deposition temperatures were achieved.
Objects and the Web (2002)

Good design practices are increasingly important in Web development. The authors apply such practices using a framework for layered architectures based on the Smalltalk GUI development pattern of model-view-controller.
Hot compressed water—a suitable and sustainable solvent and reaction medium? (2004)

Hot compressed water in the sub- and supercritical state exhibits exciting physical and chemical properties, which can be varied continuously from gas-like to liquid-like behaviour. Correspondingly, the solvent properties can change from non-polar behaviour as present, for example, in organic solvents to highly ionic characteristics like in salt melts. This opens up several promising opportunities for separation processes and chemical reactions. Under supercritical conditions, substantial amounts of gases and organic substances can homogeneously be mixed with water, which then can be separated by adjusting the subcritical conditions by forming additional phases. This can beneficially be combined with chemical reactions occurring in the homogeneous state leading to integrated processes, which are more effective and competitive. Three approaches to the technical application of hot compressed water are presented to show and discuss the technology, potential, technical hurdles and future research demand in this area of research and development.
Fiber optic illumination by laser activated remote phosphor (2012)

For some fiber optic applications, like high-end endoscopy, light sources with high luminance are necessary. Currently, short arc discharge lamps are being used. However, more and more LED solutions are trying to compete, but they can not yet reach the performance obtainable by 300 W Xenon short arc discharge lamps. To make this field of application accessible for solid state light sources, a new approach is necessary. Diode lasers have rapidly advanced in the past years. This is particularly true for multimode laser diodes emitting at around 445 nm wavelength. Single diodes emitting more than 1 W of optical power are already available. These laser sources exhibit extremely high radiance, thus they can be focused onto very small areas. Phosphors placed near the focus can result in high luminance sources. On the basis of this idea, a device has been developed to match the performance of a state of the art 300 W Xenon lamp system. An array of laser diodes is used to illuminate a phosphor plate which converts the blue pump light into yellow light. The converted light is collected and adapted to the application by a tapered TIR rod. To achieve a color point on the Planckian locus at 6000 K, the light of an LED emitting at around 460 nm is superimposed to the converted light.
Role for intracellular proteases in the processing and transport of class II HLA antigens. (1988)

Human B-lymphoblastoid cell lines (B-LCL) incubated with the protease inhibitor leupeptin accumulate complexes of class II HLA antigens with a series of Mr 21,000-23,000 basic proteins termed leupeptin-induced proteins (LIP). The appearance of class II antigen-associated LIP coincides with the disappearance of class II antigen-associated invariant (I) chain. Glycopeptides generated by in vitro proteolysis of LIP and I chain using Staphylococcus aureus V8 protease are identical as determined by electrophoresis in sodium dodecyl sulfate. These results suggest that LIP is a proteolytic product derived from the I chain and are consistent with the view that further in vivo proteolysis of LIP by a leupeptin-sensitive enzyme normally facilitates its release from class II antigens. Incubation of B-LCL with monensin, which traps class II antigens and associated I chain in the Golgi apparatus, or chloroquine, which neutralizes intracellular acidic compartments and inhibits I-chain dissociation, blocks the leupeptin-induced appearance of LIP. Treatment of LIP with endoglycosidases F and H shows that both of its N-linked oligosaccharides are in the complex form, indicating that proteolysis of class II antigen-associated I chain to generate LIP occurs in a late-Golgi or post-Golgi compartment. The compartment in which these proteolytic events occur may be identical to the site in macrophages and B lymphocytes where foreign antigens are processed and interact with class II HLA molecules.
Diseases Classification on Cotton leaves by Advance Digital Image Processing Approach (2012)

In identifying and diagnosing cotton disease the pattern of disease is the important part. Various features of the image can be extracted viz. color of the infected part and by applying various color windows to the disease image and after that we obtained the vector value for this image, also similar procedure is applied for the normal cotton leaf image and that values compared with one another and vector distance is calculated and depending upon that vector distance the disease is identified and based upon this diagnosis is possible.
Interactive Visualizations on Large and Small Displays: The Interrelation of Display Size, Information Space, and Scale (2013)

In controlled experiments on the relation of display size (i.e., the number of pixels) and the usability of visualizations, the size of the information space can either be kept constant or varied relative to display size. Both experimental approaches have limitations. If the information space is kept constant then the scale ratio between an overview of the entire information space and the lowest zoom level varies, which can impact performance; if the information space is varied then the scale ratio is kept constant, but performance cannot be directly compared. In other words, display size, information space, and scale ratio are interrelated variables. We investigate this relation in two experiments with interfaces that implement classic information visualization techniques-focus+context, overview+detail, and zooming-for multi-scale navigation in maps. Display size varied between 0.17, 1.5, and 13.8 megapixels. Information space varied relative to display size in one experiment and was constant in the other. Results suggest that for tasks where users navigate targets that are visible at all map scales the interfaces do not benefit from a large display: With a constant map size, a larger display does not improve performance with the interfaces; with map size varied relative to display size, participants found interfaces harder to use with a larger display and task completion times decrease only when they are normalized to compensate for the increase in map size. The two experimental approaches show different interaction effects between display size and interface. In particular, focus+context performs relatively worse at a large display size with variable map size, and relatively worse at a small display size with a fixed map size. Based on a theoretical analysis of the interaction with the visualization techniques, we examine individual task actions empirically so as to understand the relative impact of display size and scale ratio on the visualization techniques' performance and to discuss differences between the two experimental approaches.
University of Wisconsin solution provides superior myocardial preservation compared with Stanford cardioplegic solution. (1995)

The efficacy of the University of Wisconsin solution to safely prolong preservation times for kidney, pancreas, and liver transplantation is established, but its efficacy in enhancing myocardial preservation is not yet clear. We studied the effects of Stanford cardioplegic solution and the University of Wisconsin solution both in preserving the myocardium and in protecting it from the effects of reperfusion injury after 6 hours of preservation. In 28 rat hearts we measured changes in high-energy phosphate content (with magnetic resonance spectroscopy) and histologic changes (edema, endothelial changes, myocyte architecture) during preservation and changes in high-energy phosphate content, histologic status, and performance (aortic systolic and diastolic pressure, heart rate, rhythm) in Langendorff and working hearts during reperfusion. No significant differences in the kinetics of high-energy phosphate changes were noted between the two cardioplegic solutions during preservation. However, at the end of 6 hours of preservation, hearts in the Stanford cardioplegic solution group were more edematous (p < 0.01) than those in the University of Wisconsin group. During reperfusion, no significant differences in the kinetics of high-energy phosphates were noted between the two cardioplegic solutions. None of the hearts in the University of Wisconsin solution group developed ventricular fibrillation at the start of reperfusion, but all hearts in the Stanford group did so. Once sinus rhythm was established no significant differences in developed pressure or heart rate were found between the two solutions. After 2.5 hours of reperfusion, hearts in the Stanford group were more edematous (p < 0.002) and had a greater disruption of myocyte architecture (p < 0.002) and greater arteriolar endothelial injury (p < 0.004). In conclusion, the University of Wisconsin solution better protects the myocardium in this rat model than does Stanford solution. The mechanism for this beneficial effect of the University of Wisconsin solution appears to be due to its better preservation of the microvasculature rather than differences in preservation of high-energy phosphates.