gebhart/patrepeval huggingface dataset:
The Absorption Spectrum of Fluorine<sup>1</sup> (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Absorption Spectrum of Fluorine1Robert K. Steunenberg and Richard C. VogelCite this: J. Am. Chem. Soc. 1956, 78, 5, 901–902Publication Date (Print):March 1, 1956Publication History Published online1 May 2002Published inissue 1 March 1956https://pubs.acs.org/doi/10.1021/ja01586a007https://doi.org/10.1021/ja01586a007research-articleACS PublicationsRequest reuse permissionsArticle Views635Altmetric-Citations95LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparison and Analysis between Distinguish Clustering Protocols of Wireless Sensor Networks (A Survey) (2016)

A WSN as a finest having rules i.e. energy (power) validation from every sensor hub is comprised the battery or energy device with a restricted energy (power) provide to job. Likewise, not easy task to replace the battery in different environment there may be very rough or exhaustive in a few different situations. On the other side, the wireless sensor network says that there may be enough energy to complete the task or can gather the information easily. There are so many clustering protocol to maximize the life cycle of network in WSN. This will be a typical to task to create the mind relax system that can help to collect the data and as well as less energy usage. In this paper, focus on different clustering protocols with different parameters that suggest which one protocol is better for the nodes into hostile area & further to improvement of energy usage should be less.
Identification of Allosteric Sites in Rabbit Phosphofructo-1-kinase (1999)

Earlier studies indicated an evolutionary relationship between bacterial and mammalian phosphofructo-1-kinases (PFKs) that suggests duplication, tandem fusion, and divergence of catalytic and effector binding sites of a prokaryotic ancestor to yield in eukaryotes a total of six organic ligand binding sites. The identities of residues involved in the four binding sites for allosteric ligands in mammalian PFK have been inferred from this assumed relationship. In the current study of the C isozyme of rabbit PFK, two arginine residues that can be aligned with important residues in the catalytic and allosteric binding sites of bacterial PFK and that are conserved in all eukaryotic PFKs were mutated. Arg-48 was suggested previously to be part of either the ATP inhibitory or the adenine nucleotide activating site. However, the mutant enzyme showed only slightly less sensitivity to ATP inhibition and was fully activatable by adenine nucleotides. On the other hand, sensitivity to citrate and 3-phosphoglycerate inhibition was lost, indicating an important role for Arg-48 in the binding of these allosteric effectors. Mutation of Arg-481, homologous to an active site residue in bacterial PFK, prevented binding and allosteric activation by fructose 2,6-bisphosphate. A new relationship between the allosteric sites of mammalian PFK and bacterial PFK is proposed.
Multiple Full-length NS3 Molecules Are Required for Optimal Unwinding of Oligonucleotide DNA in Vitro (2005)

NS3 (nonstructural protein 3) from the hepatitis C virus is a 3' --> 5' helicase classified in helicase superfamily 2. The optimally active form of this helicase remains uncertain. We have used unwinding assays in the presence of a protein trap to investigate the first cycle of unwinding by full-length NS3. When the enzyme was in excess of the substrate, NS3 (500 nM) unwound >80% of a DNA substrate containing a 15-nucleotide overhang and a 30-bp duplex (45:30-mer; 1 nM). This result indicated that the active form of NS3 that was bound to the DNA prior to initiation of the reaction was capable of processive DNA unwinding. Unwinding with varying ratios of NS3 to 45:30-mer allowed us to investigate the active form of NS3 during the first unwinding cycle. When the substrate concentration slightly exceeded that of the enzyme, little or no unwinding was observed, indicating that if a monomeric form of the protein is active, then it exhibits very low processivity. Binding of NS3 to the 45:30-mer was measured by electrophoretic mobility shift assays, resulting in K(D) = 2.7 +/- 0.4 nM. Binding to individual regions of the substrate was investigated by measuring the K(D) for a 15-mer oligonucleotide as well as a 30-mer duplex. NS3 bound tightly to the 15-mer (K(D) = 1.3 +/- 0.2 nM) and, surprisingly, fairly tightly to the double-stranded 30-mer (K(D) = 11.3 +/- 1.3 nM). However, NS3 was not able to rapidly unwind a blunt-end duplex. Thus, under conditions of optimal unwinding, the 45:30-mer is initially saturated with the enzyme, including the duplex region. The unwinding data are discussed in terms of a model whereby multiple molecules of NS3 bound to the single-stranded DNA portion of the substrate are required for optimal unwinding.
Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells (2009)

In this work, we have developed new aptamer probes for non-small cell lung cancer (NSCLC) by directing the aptamer selection process against the living cells of adenocarcinoma, the most common subtype of NSCLC. A panel of single-stranded DNA (ssDNA) aptamers were generated and evaluated for adenocarcinoma cell recognition. The aptamers bound to the adenocarcinoma cells with dissociation constants in the nanomolar range and the binding of the selected aptamers to the adenocarcinoma cells were significantly stronger than the other cancerous lung cells as well as other types of cancer cells. Moreover, the application of the aptamers to the clinical tissue section samples showed the differentiation of adenocarcinoma from normal lung tissue and other subtypes of lung cancer. The aptamers are expected to be new molecular probes for the investigation of the molecular bases of different NSCLC subtypes and their biological heterogeneity, which is valuable for advancing NSCLC diagnosis and treatment.
Hybrid V2X Communications: Multi-RAT as Enabler for Connected Autonomous Driving (2018)

Exploiting the full potential of automated driving systems requires reliable wireless communication enabling network connectivity and cooperation among vehicles. Multiple V2X technologies are addressing the requirements of connected autonomous driving applications. Recent investigations have shown that none of the technologies is flexible and reliable enough to serve the diverse requirements in terms of delay, reliability and throughput under the various circumstances observed by vehicles. Hybrid V2X communications enables the coordination of multiple communication technologies to efficiently adapt to the time-varying channel and road traffic conditions. Further it allows to increase reliability and throughput of transmissions by combining multiple RATs in parallel. This work gives an overview of the potential, challenges and main design aspects of hybrid V2X communications considering the latest technological developments.
First demonstration of diode-type 3-D NAND flash memory string having super-steep switching slope (2017)

Super-steep switching is successfully demonstrated using positive feedback (PF) in fabricated diode-type 3-D NAND flash memory strings. Thanks to the PF, the subthreshold swing (SS) measured in a cell of a string during read operation is less than 1 mV/dec at turn-on voltage (V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> ) regardless of the polarity and the amount of the charge stored in the cell. This string has memory characteristics similar to conventional FET-type string while keeping much better SS than that of the FET-type string even after program/erase (P/E) cycling.
Dealkylation of Dialkyl Phosphonates with Boron Tribromide (2001)

Boron tribromide cleanly and quantitatively converts dimethyl-, diethyl-, diisopropyl-, and ditertiobutyl phosphonates RP(O)(OR′)2 into the corresponding phosphonic acids RP(O)(OH)2 via methanolysis. The use of boron tribromide is compatible with a variety of functionalities in the R group.
Investigational Use of Tissue Plasminogen Activator (t‐PA) for Occluded Central Venous Catheters (1990)

Urokinase and streptokinase are commonly used thrombolytic agents for fibrin obstructed central venous catheters. Although proven to be efficacious, these two agents have the potential to induce systemic fibrin breakdown and hemorrhage. We report our initial experience with tissue plasminogen activator (t-PA) for the treatment of occluded central venous catheters which failed urokinase. Of 25 incidents of catheter occlusion in 142 right atrial catheters, six failed to clear after an initial bolus dwell of urokinase. Five of these six catheters cleared following treatment with 2 mg/2 cc of t-PA with a mean of 1.5 bolus installations. The one catheter failure was due to catheter tip position and age of clot. No coagulation abnormalities or bleeding was observed. These data suggest that t-PA may be a safe, effective thrombolytic agent in the treatment of occluded central venous catheters.
Three-dimensional CT image segmentation by volume growing (1991)

The research reported in this paper is aimed at locating, identifying, and quantifying internal (anatomical or physiological) structures, by 3-D image segmentation. Computerized tomography (CT) images of an object are first processed on a slice-by-slice basis, generating a stack of image slices that have been smoothed and pre-segmented. The image smoothing operation is executed by a spatially adaptive filter, and the 2-D pre-segmentation is achieved by a thresholding process whereby each individual pixel in the input image space is consistently assigned a label, according to its CT number, i.e., the gray-level value. Given a sequence of pre-segmented images as 3-D input scene (a stack of image slices), the spatial connectivity that exists among neighboring image pixels is utilized in a volume growing process which generates a number of well-defined volumetric regions or image solides, each representing an individual anatomical or physiological structure in the input scene. The 3-D segmentation is implemented using a volume growing process so that the aspect of pixel spatial connectivity is incorporated into the image segmentation procedure. To initialize the volume growing process for each volumetric region in the input 3-D scene, a seed location for a region is defined and loaded into a queue data structure called seed queue. The volume growing process consists of a set of procedures that perform different operations on the volumetric data of a CT image sequence. Examples of experiment of the described system with CT image data of several hardwood logs are given to demonstrate usefulness and flexibility of this approach. This allows solutions to industrial web inspection, as well as to several problems in medical image analysis where low-level image segmentation plays an important role toward successful image interpretation tasks.
DCAS-based concurrent deques supporting bulk allocation (2002)

Although functional status in adolescents and adults with Fontan circulation was good, arrhythmia and liver dysfunction in such subjects could lead to morbidity.
Physicians' preferences for information sources: a meta-analytic study. (1997)

Identification of the resources physicians use to acquire information for clinical practice and medical research is an important area of research for health sciences librarianship and medical practice. During the past twenty years several studies have addressed questions about physicians' preferences for information sources, but generalization from the results of these studies has been hampered by limited sampling, diverse methods, and varied reportorial formats. Meta-analysis provides a method for reducing these limits. Using a meta-analytic procedure, this study reviews twelve studies published between 1978 and 1992, categorizes and ranks the physicians' preferred information sources reported in each study, then aggregates and counts the frequencies of the top six preferences, as well as the associated first and second preferences, for all the study populations or their strata. The results indicate that physicians prefer to obtain information from journals and books, but also that they often consult colleagues to get answers to clinical and research questions. The implications of these findings for health sciences librarianship are briefly discussed.
Color Image Segmentation (2012)

An intuitive way of color image segmentation is through clustering in which each pixel in an image is treated as a data point in the feature space. A feature space is effective if it can provide high distinguishability among objects in images. Typically, in the preprocessing phase, various modalities or feature spaces are considered, such as color, texture, intensity, and spatial information. Feature selection or reduction can also be understood as transforming the original feature space into a more distinguishable space (or subspaces) for distinguishing different content in an image. Most clustering-based image segmentation algorithms work in the full feature space while considering the tradeoff between efficiency and effectiveness. The authors’ observation indicates that often time objects in images can be simply detected by applying clustering algorithms in subspaces. In this paper, they propose an image segmentation framework, named Hill-Climbing based Projective Clustering (HCPC), which utilizes EPCH (an efficient projective clustering technique by histogram construction) as the core framework and Hill-Climbing K-means (HC) for dense region detection, and thereby being able to distinguish image contents within subspaces of a given feature space. Moreover, a new feature space, named HSVrVgVb, is also explored which is derived from Hue, Saturation, and Value (HSV) color space. The scalability of the proposed algorithm is linear to the dimensionality of the feature space, and our segmentation results outperform that of HC and other projective clustering-based algorithms.
Molecular Cloning of Two Alternatively Spliced Forms of Human Phosphatidic Acid Phosphatase cDNAs that Are Differentially Expressed in Normal and Tumor Cells (1998)

Phosphatidic acid (PA) and diacylglycerol (DG) are lipids involved in signal transduction and in structural membrane-lipid biosynthesis in cells. Phosphatidic acid phosphatase (PAP) catalyzes the conversion of PA to DG. This enzyme exists in at least two isoforms, one of which (PAP1) is presumed to be cytosolic and membrane associated and the other (PAP2) to be an integral membrane protein. Homology search of the GenBank database using a murine sequence probe enabled the cloning of several putative human isoenzymes. Two isoforms, presumed to be alternative splice variants from a single gene, designated as PAP2-alpha1 and PAP2-alpha2, have been cloned and expressed. The PAP2-alpha1 and PAP2-alpha2 have a 84% and a 72% overall match, respectively, with the published mouse PAP amino acid sequence. The area of alternative exon usage was confined to the coding region at amino acids 20 to 70. Ectopic expression of PAP2-alpha1 and PAP2-alpha2 cDNAs in ECV304 endothelial cells led to a 6- to 8-fold and a 2-fold increase in PAP activity, respectively, in cell-free extracts using an in vitro assay that measured the conversion of [14C]PA to [14C]DG. The increase in PAP activity in PAP2-alpha-transfected cells correlated with a >50% decrease in the steady-state PA level. Northern analysis showed that PAP2-alpha mRNA expression was suppressed in several tumor tissues, notably those derived from the lower alimentary tract. Subsequent analysis of colon tumor tissue derived from four donors confirmed lower expression of PAP2-alpha than in matching normal colon tissue. Considering these data and previous demonstrations that certain transformed cell lines have lower PAP activity, we suggest that human PAP cDNAs may be candidates for gene therapy for certain tumors.
FMKe: A realistic benchmark for key-value stores (2018)

Standard benchmarks are essential tools to evaluate and compare database management systems in terms of relevant semantic properties and performance. They provide the means to evaluate a system with workloads that mimic real applications. Although a number of realistic benchmarks already exist for relational database systems, the same cannot be said for NoSQL databases. This latter class of data storage systems has become increasingly relevant for geo-distributed systems, and this has led developers and researchers to either rely on benchmarks that do not model realistic workloads or to adapt the aforementioned benchmarks for relational databases to work for NoSQL databases, in a somewhat ad-hoc fashion. Since these benchmarks assume an isolation and transactional model in the database, they are inherently inadequate to evaluate NoSQL databases. In this thesis, we propose a new benchmark that addresses the lack of realistic evaluation tools for distributed key-value stores. We consider a workload that is based on information we have acquired about a real world deployment of a large-scale application that operates over a distributed key-value store, that is responsible for managing patient prescriptions at a nation-wide level in Denmark. We design our benchmark to be extensible to a wide range of distributed key-value storage systems and some relational database systems with minimal effort for programmers, which only need to design and implement specific data storage drivers to benchmark different alternatives. We further present a study on the performance of multiple database management systems in different deployment scenarios.
Nonlinear Mapping of Gaussian Statistics: Theory and Applications to Spacecraft Trajectory Design (2006)

Peer Reviewed
Analyzing the Nature of Knowledge in the IS Field (2003)

The history of the IS field is no more than fifty years.This can be considered relatively new compared to more developed disciplines such as the social sciences or the natural sciences.However, the field of IS has long been criticized based on the nature of knowledge in its domain.Moreover, the diversity and pluralism of methodologies adopted by researchers and lack of a coherent body of knowledge in the IS field invites additional criticism.This brings to the fore the important question about organization of knowledge in the field of information systems whether it can be considered as coherent, scientific or cumulative (considered generally as important factors in judging the soundness of a discipline and categorizing it as an independent academic discipline).The other related question is whether there could be alternative or possibly better ways for a discipline to organize knowledge in forms other than theories.We believe that criticisms of the IS field for lack of well-established theories or multiplicity of views of IS researchers appear to be misplaced.In this paper, we respond to some of these criticisms.Our suggestion is that diversity of views or lack of established theories in the field should not be used as the basis for criticizing the IS field as a core body of knowledge.Such criticisms should rather focus on judging whether knowledge accumulated over time in the IS field has a scientific character.We contend that the IS field is still evolving while other disciplines such as the social sciences or the natural sciences have matured over the last couple of centuries.In view of the still emerging nature of the IS field, we adopt the premise that comparison of the state of knowledge in the IS field with that in other established disciplines does not seem logical and this, in itself highlights the weakness in the argument of the critics of the IS field.Since the nature or the way knowledge is organized in a field is usually an important criterion for assessing the academic character of the field, an alternative framework for organizing knowledge in the IS field is suggested that can help accord the status of an academic discipline to IS field.
Histogram specification of 24-bit color images in the color difference <inline-formula>(C-Y)</inline-formula> color space (1999)

The <i>Journal of Electronic Imaging</i> (JEI), copublished bimonthly with the Society for Imaging Science and Technology, publishes peer-reviewed papers that cover research and applications in all areas of electronic imaging science and technology.
Parametric localization of multiple incoherently distributed sources using covariance fitting (2003)

A new algorithm for parametric localization of multiple incoherently distributed sources is proposed. Our algorithm is based on an approximation of the array covariance matrix using central and non-central moments of the source angular power densities. Based on this approximation, a new computationally simple covariance fitting-based technique is proposed to estimate these moments. The source parameters are then obtained from the moment estimates. Compared to earlier algorithms, our technique has lower computational cost and obtains the parameter estimates in a closed form. Also, it can be applied to scenarios with multiple sources that may have different angular power densities while other known methods are not applicable to such scenarios.
Consequences and Predictors of Depression in Patients With Chronic Heart Failure: Implications for Nursing Care and Future Research (2006)

Depression is common among patients with chronic heart failure (HF) and leads to more symptoms of HF, decreased quality of life, and an increased risk for premature death. Depressed HF patients also use more health care resources, which increases the economic burden on the health care system. The assessment of risk factors of depression such as age younger than 60-65 years, poor physical functioning, previous depression, poor self-efficacy, living alone, and distressful relationships, in combination with the use of depression instruments, can be helpful in detecting depression in HF patients. Unfortunately, interventions on how to relieve depression in patients with HF have not been investigated thoroughly; however, depression agents as well as HF education, social support, exercise therapy, stress management, and relaxation have been shown to be useful interventions. Because of poor outcomes, studies that examine the effectiveness and/or side effects of pharmacologic as well as nonpharmacologic interventions on depressed patients with HF are needed.