gebhart/patrepeval huggingface dataset:
Hierarchical fault tolerance memory architecture with 3-dimension interconnect (2007)

This paper proposed hierarchical fault tolerance techniques for ultrahigh-density memories based on 3- dimension interconnect technology. It describes how to implement hierarchical architecture with different granularity redundancies and how to combine error correction code (ECC), built-in self-test (BIST), built-in repair-analysis (BIRA), and built-in self-repair (BISR) capabilities. Simulation is employed to estimate the memory behavior of various configurations, and experimental results indicate that the proposed method has substantial reliability improvements over conventional techniques. For a memory with 1% bit-level failure rate and 50% device-level defect density, the proposed method can gain 100% reliability by using less than 30% extra overhead. It proves the availability of the proposed architecture.
Identification of a Sphingolipid α-Glucuronosyltransferase That Is Essential for Pollen Function in<i>Arabidopsis</i>      (2014)

Glycosyl inositol phosphorylceramide (GIPC) sphingolipids are a major class of lipids in fungi, protozoans, and plants. GIPCs are abundant in the plasma membrane in plants, comprising around a quarter of the total lipids in these membranes. Plant GIPCs contain unique glycan decorations that include a conserved glucuronic acid (GlcA) residue and various additional sugars; however, no proteins responsible for glycosylating GIPCs have been identified to date. Here, we show that the Arabidopsis thaliana protein INOSITOL PHOSPHORYLCERAMIDE GLUCURONOSYLTRANSFERASE1 (IPUT1) transfers GlcA from UDP-GlcA to GIPCs. To demonstrate IPUT1 activity, we introduced the IPUT1 gene together with genes for a UDP-glucose dehydrogenase from Arabidopsis and a human UDP-GlcA transporter into a yeast mutant deficient in the endogenous inositol phosphorylceramide (IPC) mannosyltransferase. In this engineered yeast strain, IPUT1 transferred GlcA to IPC. Overexpression or silencing of IPUT1 in Nicotiana benthamiana resulted in an increase or a decrease, respectively, in IPC glucuronosyltransferase activity in vitro. Plants in which IPUT1 was silenced accumulated IPC, the immediate precursor, as well as ceramides and glucosylceramides. Plants overexpressing IPUT1 showed an increased content of GIPCs. Mutations in IPUT1 are not transmitted through pollen, indicating that these sphingolipids are essential in plants.
Deprotonation and Addition Reactions of Frustrated Lewis Pairs with Alkynes (2010)

Deprotonation of terminal alkynes is effected by the treatment with tBu3P and B(C6F5)3 to give [tBu3PH][PhCCB(C6F5)3] (1a) and [tBu3PH][RCCB(C6F5)3] (R = nBu 2, tBu 3, Me3Si 4, and CpFe(C5H4) 5). In a similar fashion, FLP deprotonation of 1,4-diethynylbenzene was employed to prepare the salt [tBu3PH]2[(C6F5)3BCC(C6H4)CCB(C6F5)3] (6). As well, use of differing Lewis acids afforded the species [tBu3PH][PhCCEAr3] (EAr3 = Al(C6F5)3 7, PhB(C6F5)2 8, BPh3 9). The corresponding reaction of Me3SiCCSiMe3 afforded [tBu3PSiMe3][Me3SiCCB(C6F5)3] (10). For less basic phosphines, phosphine/borane addition reactions were observed with alkynes. Thus the species E-R3P(Ph)C═C(H)B(C6F5)3 (R = o-tol 11, Ph 12) were prepared. In the latter case, Ph3P·B(C6F5)3 was employed. Similarly, E-Ph3P(CpFe(C5H4))C═C(H)B(C6F5)3 (13), E-Ph3P(Ph)C═C(Me)B(C6F5)3 (14), E-R2PH(Ph)C═C(H)B(C6F5)3 (R = Ph 15, C6H2Me3 16), and E-(C6H2tBu3)PH2(Ph)C═C(H)B(C6F5)3 (17) were prepared. Again, variation in the Lewis acid afforded E-Ph3P(Ph)C═C(H)EAr3 (EAr3 = PhB(C6F5)2 18, Al(C6F5)3 19), E-Ph3P(nBu)C═C(H)Al(C6F5)3 (20), and E-(o-tol)3P(Ph)C═C(H)Al(C6F5)3 (21). The macrocyclic [(H)C═C(Ph)Mes2PC6F4B(C6F5)2]2 (22) was prepared from the analogous alkyne addition to Mes2PC6F4B(C6F5)2, while E-Ph2PCH2CH2PPh2(Ph)C═C(H)B(C6F5)3 (23) and E-(CH2PPh2(Ph)C═C(H)B(C6F5)3)2 (24) were derived from the reactions of Ph2PCH2CH2PPh2. The related addition reaction involving 1,4-diethynylbenzene gave E-HC≡CC6H4C(PPh3)═C(H)B(C6F5)3 (25), while subsequent reaction with tBu3P and B(C6F5)3 yielded the unusual salt/zwitterion [tBu3PH][(C6F5)3BCC≡C6H4C(PPh3)═C(H)-B(C6F5)3] (26). Reaction of PhCH2NMe2 with PhCCH and B(C6F5)3 gave give a 84:16 mixture of [PhCH2NMe2H][PhCCB(C6F5)3] (27a) and PhCH2NMe2(Ph)C═C(H)B(C6F5)3 (27b), while imines were used to prepare [(tBu)HN═CHPh][PhCCB(C6F5)3] (28) and [(tBu)HN═CPh2][PhCCB(C6F5)3] (29). The corresponding reaction of tBuNCNtBu, B(C6F5)3, and two equivalents of PhCCH led to the unusual product [tBuNCN(H)C(Ph)═C(H)tBu][PhCCB(C6F5)3] (30). Finally, non-pnictogen Lewis bases were explored. The reaction of the N-heterocyclic carbene ItBu with B(C6F5)3 and PhCCH was shown to yield the deprotonation product [ItBuH][PhCCB(C6F5)3] (31), while the sulfides R2S gave E-R2S(Ph)C═C(H)B(C6F5)3 (R = Me 32, PhCH2 33). The formation of these latter sulfide zwitterions was demonstrated to be reversible.
A Unified Context for Spherulitic Growth in Polymers (1998)

The long-standing issue, central to polymer science, of the relevance of cellulation to the formation of spherulites has been resolved by the first demonstration of this phenomenon, in spherulites of a highly branched polyethylene copolymer. The two principal alternative mechanisms proposed for the formation of spherulites are shown to be complementary, with cellulation a secondary process occurring only when segregation reduces growth rate sufficiently. A unified context for polymeric crystallization is thereby achieved in which segregation generally plays a passive rather than an active role in the development of spherulites.
Untersuchungen zur Eiweißbindung von Arzneistoffen durch kontinuierliche Ultrafiltration, 4. Mitt. (1982)

Abstract Die Proteinbindung der Titelverbindungen ist stark von der Substitution des Aromaten im 3‐(3‐Oxo‐1‐phenylbutyl)‐rest abhängig. Bei unsubstituiertem Aromaten sowie bei einer Methoxygruppe in 4‐Position liegt die Eiweißbindung in der Größenordnung von Warfarin. Dichlorsubstitution in 3‐ und 4‐Position verstärkt die Bindung um eine Zehnerpotenz.
Sentence Extraction by tf/idf and Position Weighting from Newspaper Articles. (2002)

Recently, lots of researchers are focusing their interests on the development of summarization systems from large volume sources combined with knowledge acquisition techniques such as information extraction, text mining or information retrieval. Some of these techniques are implemented according to the specific knowledge in the domain or the genre from the source document. In this paper, we will discuss Japanese Newspaper Domain Knowledge in order to make a summary. My system is implemented with the sentence extraction approach and weighting strategy to mine from a number of documents.
The Fabrication and Analysis of Bifacial Solar Cells from Dendritic Web Silicon Substrates (1987)

Bifacial solar cells, which respond to light incident on either the front or the back surface, have been fabricated using dendritic web silicon as the substrate material. Both p‐type and n‐type substrates have been used, with resistivity ranging from 0.2 to 100 Ω‐cm for p‐type and from 0.2 to 10 Ω‐cm for n‐type. The thickness of the web substrates varied from 100 to 160 μm. The performance of the cells was found to depend strongly on substrate resistivity, with the highest resistivity giving the best results. Efficiencies in excess of 15% under front illumination, and approaching 15% under back illumination, have been measured. The efficiency under back illumination decreases dramatically with resistivity because of a decrease in minority carrier diffusion length, as deduced from measurements of internal quantum efficiency. The ratio of short‐circuit current under back illumination to short‐circuit current under front illumination also decreases with illumination level below 1 sun. The observed effects of resistivity and illumination level on cell performance are throught to be a consequence of the presence of extended defects (dislocations decorated with precipitates) in web material.
Single‐cell genomics based on Raman sorting reveals novel carotenoid‐containing bacteria in the Red Sea (2016)

Cell sorting coupled with single-cell genomics is a powerful tool to circumvent cultivation of microorganisms and reveal microbial 'dark matter'. Single-cell Raman spectra (SCRSs) are label-free biochemical 'fingerprints' of individual cells, which can link the sorted cells to their phenotypic information and ecological functions. We employed a novel Raman-activated cell ejection (RACE) approach to sort single bacterial cells from a water sample in the Red Sea based on SCRS. Carotenoids are highly diverse pigments and play an important role in phototrophic bacteria, giving strong and distinctive Raman spectra. Here, we showed that individual carotenoid-containing cells from a Red Sea sample were isolated based on the characteristic SCRS. RACE-based single-cell genomics revealed putative novel functional genes related to carotenoid and isoprenoid biosynthesis, as well as previously unknown phototrophic microorganisms including an unculturable Cyanobacteria spp. The potential of Raman sorting coupled to single-cell genomics has been demonstrated.
Antibacterial activity of ruthenium nanoparticles synthesized using Gloriosa superba L. leaf extract (2014)

This work reports an ecofriendly approach for the synthesis of Ruthenium nanoparticles (Ru NPs) using aqueous leaf extract of Gloriosa superba. G. superba contains cholidonic, superbine, colchicine, gloriosol, phytosterils and stigmasterin, which are found to be responsible for the bio-reduction of Ru NPs. The synthesized Ru NPs were characterized using UV–Vis spectroscopy, Fluorescence spectra, FTIR, XRD, SEM and EDX analyses. UV–Vis spectra of the aqueous medium containing Ru NPs showed a gradual decrease of the absorbance peak observed at 494 nm. Fluorescence spectra of Ru NPs emission (λem) exhibited at 464 nm are attributed to the Ru=N π bonds transition. The biomolecules responsible for the reduction of Ru NPs were analyzed by FTIR. XRD results confirmed the presence of Ru NPs with hexagonal crystal structure. The calculated crystallite sizes using Scherrer formula are in the range from 25 to 90 nm. Scanning electron microscopy ascertained spherical nature of the Ru NPs. The EDX analysis showed the complete elemental composition of the synthesized Ru NPs. The synthesized Ru NPs exhibited good antibacterial performance against gram-positive and gram-negative bacterial strains, which was studied using standard disc diffusion method. The synthesis of Ru NPs by this method is rapid, facile and can be used for various applications.
Great Britain in Egypt (1928)

Great Britain in Egypt Great Britain in Egypt. By E. W. Polson Newman, B.A., F.R.G.S., with Foreword by J. G. Maxwell, P.C.,G.C.B., K.C.M.G., C.V.O., D.S.O. 1928. (London: Cassell & Co., Ltd. 8vo. xvi + 304 pp. 15s.) H. L. H. L. Search for other works by this author on: Oxford Academic Google Scholar Journal of the Royal Institute of International Affairs, Volume 7, Issue 6, November 1929, Pages 441–442, https://doi.org/10.2307/3014961 Published: 01 November 1928
Genome editing of Clostridium autoethanogenum using CRISPR/Cas9 (2016)

Addition of both an inducible promoter library and a scarless genome editing tool is an important expansion to the genetic tool box of industrial <i>C. autoethanogenum</i> strain.
The art of game-mastering pervasive games (2008)

Pervasive Games can benefit greatly from being game-mastered rather than fully automatic. However, game-mastering pervasive games is not a simple task neither from a technical nor a game design perspective.In this article we discuss some of the core issues for pervasive game mastering based on two example games. The first game was a long duration pervasive larp, where the core game activity was role-play. The second game is a pervasive game which relies extensively on technology installations, and where game mastering is used to create a coherent experience mixing technology-mediated gaming with live role-play events. Based on these rather different games we outline the core issues and methods available for pervasive game mastering.
Transplantation of allogeneic CD34+ peripheral blood stem cells in patients with advanced hematologic malignancy (1996)

Sixteen patients with advanced hematologic malignancies were transplanted with HLA-identical allogeneic peripheral blood stem cells (PBSCs) that were selected for CD34+ cells by an avidin-biotin immunoadsorption technique. The median age of patients was 48 years (range, 37 to 67). Patients received 12.0 or 13.2 Gy of total body irradiation followed by 120 mg/kg of cyclophosphamide. Normal donors received 16 mg/kg of granulocyte-colony stimulating factor on days 1 to 6 followed by PBSC harvests on days 4 to 7. PBSC harvests were processed each day on a single avidin-blotin column containing an antibody to the CD34 antigen and processed cells were infused without cryopreservation daily for 4 consecutive days. Prophylaxis against graft-versus-host disease (GVHD) consisted of cyclosporine alone for 5 patients and CSA plus methotrexate for 11 patients. A median of 18.64 (6.74 to 34.97) x 10(8) CD34+ cells/kg patient body weight were collected from each donor. A median of 8.96 (2.62 to 17.34) x 10(8) CD34+ cells/kg patient body weight were recovered after avidin-biotin adsorption which represented a median CD34+ cell yield of 53% (18% to 77%) with a median purity of 62% (34% to 82%). There was a reduction in CD3+ cells from a median of 557.26 (227.73 to 677.77) x 106/kg to 0.73 x 10(4)/kg (0.40 to 3.65), in CD4+ cells from 351.72 (194.47 to 520.11) x 10(6)/kg to 0.40 (0.15 to 1.03) x 10(4)/kg and in CD8+ cells from 169.74 (53.34 to 325.83) x 10(6)/ kg to 0.32 (0.12 to 2.71) x 10(4)/kg representing a median 2.8 (2.19 to 3.14) log reduction in T cells. One patient died of infection on day 3 posttransplant and was unevaluable for recovery of neutrophils. The median day to recovery of 500 neutrophils/mL was 15 (8 to 26) in the remaining 15 patients. Six of 16 patients falled to achieve a platelet count of 20,000/mL before death on days 3 to 97 of transplant-related complications. The median day to achieving platelets of 20,000 mL in the remaining 10 patients was 11 (7 to 31). Eight of 16 patients (50%) died between 3 and 97 days posttransplant, 7 of transplant-related causes, and 1 of progressive disease. Grade 2-4 acute GVHD occurred in 12 out of 14 (86%) and grades 3-4 in 6 out of 14 (43%) evaluable patients. Six of 8 evaluable patients developed clinical chronic GVHD and 1 developed subclinical chronic GVHD. Bone marrow and/or peripheral blood chimerism studies in 12 evaluable patients showed 97% to 100% donor type in 11 patients with 1 patient in relapse showing 40% donor cells 60 to 90 days posttransplant. Four of 16 patients (25%) are alive and disease-free 312 to 576 days after transplant. There were no episodes of graft failure or rejection. This study shows that allogeneic transplantation using CD34+ selected PBSC results in prompt and sustained engraftment. CD34+ selection, as employed in this preliminary study, however, resulted in an apparently higher rate of acute and chronic GVHD. However, The sample size is quite small and precludes a more definitive conclusion regarding GVHD.
Entropy‐Driven Helical Mesostructure Formation with Achiral Cationic Surfactant Templates (2007)

Helical mesoporous silica is synthesized using achiral cationic surfactants as template in a highly concentrated ammonia solution. The particle morphology and the helical pitch of this material could be systematically controlled by simply varying the ammonia concentration (see figure). The helical mesoporous silica was characterized by transmission electron microscopy tomography for the first time. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c2703_s.html or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
N-shift cross-orthogonal sequences (1988)

N-shift cross-orthogonal sequences and a complete complementary code derived from them are defined and discussed. A general method for generating this code is also discussed. A synchronous multiple-user spread-spectrum multiple system is proposed that uses N-shift cross-orthogonal sequences.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Semantic Parsing with Semi-Supervised Sequential Autoencoders (2016)

We present a novel semi-supervised approach for sequence transduction and apply it to semantic parsing. The unsupervised component is based on a generative model in which latent sentences generate the unpaired logical forms. We apply this method to a number of semantic parsing tasks focusing on domains with limited access to labelled training data and extend those datasets with synthetically generated logical forms.
A new electrode placement method for obtaining 12-lead ECGs (2015)

This study proved that the new method is faultless and provides better quality ECGs, no recalls and without risk for misinterpretations. Not having to remove leg garments is convenient and allows more rapid acquisition of ECGs. The forearms are freed for, intravenous, radial access, and ECGs needed during procedures. The findings have implications worldwide for patients, clinicians and technicians, and generate the need to study the method in emergency settings.
Present Status and Future Perspectives of Muscarinic Receptor Antagonists (1986)

Conventional anticholinergics (better called muscarinic antagonists) do not differentiate between subtypes of muscarinic receptors and cause unpleasant side-effects in peptic ulcer treatment. Pirenzepine, the first M1-receptor antagonist, has more selective inhibitory properties on oxyntic gastric glands and accelerates healing rates in peptic ulcer. Pirenzepine and H2-receptor antagonists interact synergistically on parietal cell function; their combination seems to be of therapeutic advantage in defined indications. Telenzepine, a pirenzepine analogue with a modified tricycle and M1-receptor selectivity, is about 10 to 25 times more potent than pirenzepine in reducing basal and stimulated gastric acid secretion in man. In patients with duodenal ulcer 3 mg telenzepine nocte seems to be as effective as 50 mg pirenzepine twice daily in regard to ulcer healing and pain relief. Another pirenzepine analogue with a modified side-chain (AF-DX 116) proved to be cardioselective in animal pharmacology, and was characterized as an M2-receptor antagonist. This might be an important step for a more profound understanding of structure-activity relationships of muscarinic receptor antagonists.
Permanent Overdrive Atrial Pacing in the Chronic Management of Recurrent Postoperative Atrial Reentrant Tachycardia in Patients with Complex Congenital Heart Disease (1997)

This study investigated the value of permanent atrial pacing as an adjunct to the current therapy in the chronic management of recurrent postoperative atrial reentrant tachycardia in patients with complex congenital heart disease. We studied the postpacing clinical course in 18 patients with recurrent atrial reentrant tachycardias unresponsive to conventional therapy who had an implanted atrial pacemaker. The pacemaker was programmed at a lower pacing rate 20% faster than the spontaneous mean daily rate previously determined with 24-hour Holter monitoring. Serial Holter recordings and pacemaker programming sessions were subsequently performed trying to maintain a paced atrial rhythm overdriving the spontaneous rhythm as long as possible. Twenty-four hour Holter monitoring documented a prevalent (> 80%) paced rhythm during the daily hours in all patients during the follow-up; all patients, however, required at least once a variation in programmed mode and pacing rate. Antiarrhythmic medications were discontinued after 6 months if the patient remained arrhythmia free while on pacing. Recurrences of atrial reentrant tachycardia occurred in five patients (29%) during the initial 6 months interval after the pacemaker implantation, while late recurrences occurred in only two patients (11%). One patient died suddenly 10 months after the pacemaker implant. At the end of the follow-up, 15 patients (83%) were arrhythmia-free and only 2 of them were still on antiarrhythmic drugs. We conclude that permanent atrial overdrive pacing can be an important tool in the management of patients with atrial reentrant tachycardia following repair of congenital heart disease.
A Transmembrane Tight Junction Protein Selectively Expressed on Endothelial Cells and Platelets (2002)

Searching for cell surface proteins expressed at interendothelial cell contacts, we have raised monoclonal antibodies against intact mouse endothelial cells. We obtained two monoclonal antibodies, 1G8 and 4C10, that stain endothelial cell contacts and recognize a protein of 55 kDa. Purification and identification by mass spectrometry of this protein revealed that it contains two extracellular Ig domains, reminiscent of the JAM family, but a much longer 120-amino acid cytoplasmic domain. The antigen is exclusively expressed on endothelial cells of various organs as was analyzed by immunohistochemistry. Immunogold labeling of ultrathin sections of brain as well as skeletal muscle revealed that the antigen strictly colocalizes in capillaries with the tight junction markers occludin, claudin-5, and ZO-1. Upon transfection into MDCK cells, the antigen was restricted to the most apical tip of the lateral cell surface, where it colocalized with ZO-1 but not with beta-catenin. In contrast to JAM-1, however, the 1G8 antigen does not associate with the PDZ domain proteins ZO-1, AF-6, or ASIP/PAR-3, despite the presence of a PDZ-binding motif. The 1G8 antigen was not detected on peripheral blood mouse leukocytes, whereas similar to JAM-1 it was strongly expressed on platelets and megakaryocytes. The 1G8 antigen supports homophilic interactions on transfected Chinese hamster ovary cells. Based on the similarity to the JAM molecules, it is plausible that the 1G8 antigen might be involved in interendothelial cell adhesion.
Sweet potato leaves: properties and synergistic interactions that promote health and prevent disease (2010)

Sweet potato (Ipomoea batatas) leaves provide a dietary source of vitamins, minerals, antioxidants, dietary fiber, and essential fatty acids. Bioactive compounds contained in this vegetable play a role in health promotion by improving immune function, reducing oxidative stress and free radical damage, reducing cardiovascular disease risk, and suppressing cancer cell growth. Currently, sweet potato leaves are consumed primarily in the islands of the Pacific Ocean and in Asian and African countries; limited consumption occurs in the United States. This comprehensive review assesses research examining the nutritional characteristics and bioactive compounds within sweet potato leaves that contribute to health promotion and chronic disease prevention. Research has affirmed the potential cardioprotective and chemopreventive advantages of consuming sweet potato leaves, thus indicating that increased consumption of this vegetable should be advocated. Since reducing the prevalence of chronic diseases is of public health concern, promoting the consumption of sweet potato leaves warrants further and more intensive research investigation.