gebhart/patrepeval huggingface dataset:
Neuristor-A Novel Device and System Concept (1962)

Certain basic problems in integration and extreme miniaturization of electronic systems may require new forms of device structure. A device structure that shows promise is hypothesized in this paper. The device is not discrete; it is rather a distributed "line," with active and passive processes so distributed that a signal propagates along the line without attenuation, much as a burning zone moves along a fuse or an ionic discharge along a nerve axon. It is shown that lines of this type can be interconnected in certain direct ways so that complete logic capability can be achieved with networks of such lines alone. Techniques of logical synthesis of these networks are introduced. Certain special properties of systems built in this fashion are delineated, especially properties that appear to be significant for the synthesis of highly-miniaturized systems. There is some discussion of physical realizability of distributed electronic structures.
Origin of dispersive effects of the Raman<b><i>D</i></b>band in carbon materials (1999)

The origin and dispersion of the anomalous disorder-induced Raman band $(D$ band) observed in all ${\mathrm{sp}}^{2}$ hybridized disordered carbon materials near 1350 ${\mathrm{cm}}^{\ensuremath{-}1}$ is investigated as a function of incident laser energy. This effect is explained in terms of the coupling between electrons and phonons with the same wave vector near the K point of the Brillouin zone. The high dispersion is ascribed to the coupling between the optic phonons associated with the D band and the transverse acoustic branch. The large Raman cross section is due to the breathing motion of these particular phonons near the K point. Our model challenges the idea that the Raman D peak is due to laser-energy-independent features in the phonon density of states, but rather is due to a resonant Raman process.
Identification of Two New Genes Conferring Resistance to <i>Colletotrichum acutatum</i> in <i>Capsicum baccatum</i> (2009)

Resistance to anthracnose, caused by Colletotrichum capsici and C. acutatum, was investigated in Capsicum baccatum PBC80 and PBC1422 and C. chinense PBC932. Mature green and ripe fruit were inoculated with 13 isolates of the two Colletotrichum species PBC80 contained the broadest spectrum of resistance to both Colletotrichum species because none of the isolates were able to infect the genotype. At both fruit maturity stages, PBC1422 was infected by only Colletotrichum acutatum. PBC932 at ripe fruit stage was infected by both C. capsici and C. acutatum, except for one isolate, 158ci, that did not infect PBC932. PBC932 at the mature green fruit stage was infected by only C. acutatum. An intraspecific cross between PBC80 and PBC1422 was developed to determine inheritance of resistance to C. acutatum. Anthracnose resistance was assessed at mature green and ripe fruit stages using 0 to 9 disease severity scores. Frequency distribution of the disease scores in the F(2) and BC(1) populations suggested a single recessive gene responsible for the resistance at mature green fruit stage and a single dominant gene for the resistance at ripe fruit stage. Linkage analysis between the two genes identified in both fruit maturity stages showed the genes to be independent. Based on phenotypic data, the two newly identified genes, co4 and Co5, from PBC80 appeared to be different loci from the co1 and co2 previously identified from PBC932 and will be valuable sources of resistance to anthracnose in chili breeding programs.
Getting started with video (1995)

Video production offers scope for the development of skills in students in many areas. When students produce their own videos they become more critically aware of the processes of media, learn the language of media through practice rather than theory and discover the relationship between media images and the audience. Children benefit most when they learn to work collaboratively, gaining skills in planning, working to a deadline and with a production focus.
The virtual reality modeling language explained (1998)

VRML stands for Virtual Reality Modeling Language. Technically, VRML is neither virtual reality nor a modeling language. Virtual reality generally implies an immersive 3D experience, which typically requires a head mounted display (HMD) and 3D input devices, such as digital gloves. VRML neither requires nor imposes immersion. Furthermore, a true modeling language would contain richer geometric modeling primitives and mechanisms. VRML provides a bare minimum of geometric modeling features but contains numerous features unavailable in a modeling language. If VRML is not virtual reality or a modeling language, what is it? This question has several answers. At its core, VRML serves as a 3D interchange format. It defines most of the commonly used semantics found in today's 3D applications such as hierarchical transformations, light sources, viewpoints, geometry, animation, fog, material properties, and texture mapping. Here's a second answer to: what is VRML? It's a 3D analog to HTML. This means that VRML serves as a simple, multiplatform language for publishing 3D Web pages. The fact that some information, including games, engineering models, scientific visualizations, educational experiences, and architecture, can best be experienced in 3D has motivated this language. Typically, these types of projects require intensive interaction, animation, and user participation and exploration beyond what a page, text, or image based format can handle. Another answer is that VRML provides the technology to integrate 3D, 2D, text, and multimedia into a coherent model.
Introduction to Logic. (1960)

Book Reviews Introduction to Logic. By Patrick Suppes. (Princeton : Van Nostrand. London: Macmillan. 1957. Pp. xviii + 312. Price 40s). Roland Hall Roland Hall Search for other works by this author on: Oxford Academic Google Scholar The Philosophical Quarterly, Volume 10, Issue 40, July 1960, Pages 287–288, https://doi.org/10.2307/2216952 Published: 01 July 1960
Hybrid switch to suppress the inrush current of AC power capacitor (2005)

This paper proposes a hybrid switch to suppress the inrush current of an ac power capacitor. This hybrid switch consists of a thyristor switch and an electromagnetic switch connected in parallel. The thyristor switch is used as an auxiliary switch during the transient state of turning on and turning off the ac power capacitor, and the electromagnetic switch is used as the main switch in the steady state. The proposed hybrid switch can avoid the inrush current of the ac power capacitor in the process of turning on and avoid the electrical arc in the process of turning off. The current rating of the thyristor switch and the electromagnetic switch used in the proposed hybrid switch is very small compared with a conventional thyristor switch or an electromagnetic switch used for switching ac power capacitor individually. Moreover, the proposed hybrid switch can extend the life of the ac power capacitor and the electromagnetic switch. A prototype is developed to demonstrate its performance. The test results show that the proposed hybrid switch module for ac power capacitor has the expected performance.
Diastereoselective Reductive Ring Expansion of Spiroketal Dihydropyranones to <i>cis</i>-Fused Bicyclic Ethers (2012)

A novel double cascade synthetic strategy was developed for the diastereoselective syntheses of cis-fused bicyclic ethers, featuring cascade Achmatowicz rearrangement/spiroketalization and cascade spiroketal reduction/oxa-Michael cyclization. Especially, the chemo-, regio-, and diastereoselective reduction of densely functionalized spiroketal dihydropyranones, followed by oxa-Michael cyclization in a one-pot fashion, was achieved.
The cloning and DNA sequence of the gene for the glutathione‐regulated potassium‐efflux system KefC of <i>Escherichia coli</i> (1991)

The kefC gene of Escherichia coli encodes a potassium-efflux system that is regulated by glutathione metabolites. The close proximity of the E. coli kefC gene to the folA gene, encoding dihydrofolate reductase, has been utilized to clone the structural gene for the system from a Clarke-Carbon plasmid. The cloned gene has been refined to a region of DNA approximately 2.1 kb in length using exonuclease III-generated deletions and random MudII1734 (lacZ) insertions. The direction of transcription has been deduced from the orientation of the Mu insertions in the cloned DNA. A hybrid protein consisting of approximately two thirds of the KefC protein fused to beta-galactosidase has been shown to be membrane-located. The DNA sequence of the gene has been determined and an open reading frame of 1.86 kb has been located which could encode a protein of 620 amino acids (79010 Da). Using the T7 expression system a membrane protein, of apparent molecular mass 55-60 kDa, has been shown to be encoded by the kefC gene. The predicted protein sequence shows a highly hydrophobic amino-terminus and a strongly hydrophilic carboxy-terminus. Comparison of the amino acid sequence of the kefC gene product with those of two glutathione-utilizing enzymes, glyoxalase and dehalogenase, has revealed some similarities.
Voltage-gated sodium ion channels in prostate cancer: expression and activity. (2002)

Our results indicate increased expression of VGSCs in Pca and VGSC involvement in Pca growth.
Markov model aided decoding for image transmission using soft-decision-feedback (2000)

Soft-decision-feedback MAP decoders are developed for joint source/channel decoding (JSCD) which uses the residual redundancy in two-dimensional sources. The source redundancy is described by a second order Markov model which is made available to the receiver for row-by-row decoding, wherein the output for one row is used to aid the decoding of the next row. Performance can be improved by generalizing so as to increase the vertical depth of the decoder. This is called sheet decoding, and entails generalizing trellis decoding of one-dimensional data to trellis decoding of two-dimensional data (2-D). The proposed soft-decision-feedback sheet decoder is based on the Bahl algorithm, and it is compared to a hard-decision-feedback sheet decoder which is based on the Viterbi algorithm. The method is applied to 3-bit DPCM picture transmission over a binary symmetric channel, and it is found that the soft-decision-feedback decoder with vertical depth V performs approximately as well as the hard-decision-feedback decoder with vertical depth V+1. Because the computational requirement of the decoders depends exponentially on the vertical depth, the soft-decision-feedbark decoder offers significant reduction in complexity. For standard monochrome Lena, at a channel bit error rate of 0.05, the V=1 and V=2 soft-decision-feedback decoder JSCD gains in RSNR are 5.0 and 6.3 dB, respectively.
Advanced Electrocatalysts with Single-Metal-Atom Active Sites (2020)

Electrocatalysts with single metal atoms as active sites have received increasing attention owing to their high atomic utilization efficiency and exotic catalytic activity and selectivity. This review aims to provide a comprehensive summary on the recent development of such single-atom electrocatalysts (SAECs) for various energy-conversion reactions. The discussion starts with an introduction of the different types of SAECs, followed by an overview of the synthetic methodologies to control the atomic dispersion of metal sites and atomically resolved characterization using state-of-the-art microscopic and spectroscopic techniques. In recognition of the extensive applications of SAECs, the electrocatalytic studies are dissected in terms of various important electrochemical reactions, including hydrogen evolution reaction (HER), oxygen evolution reaction (OER), oxygen reduction reaction (ORR), carbon dioxide reduction reaction (CO2RR), and nitrogen reduction reaction (NRR). Examples of SAECs are deliberated in each case in terms of their catalytic performance, structure-property relationships, and catalytic enhancement mechanisms. A perspective is provided at the end of each section about remaining challenges and opportunities for the development of SAECs for the targeted reaction.
Distribution of NF-κB-binding sites across human chromosome 22 (2003)

We have mapped the chromosomal binding site distribution of a transcription factor in human cells. The NF-kappaB family of transcription factors plays an essential role in regulating the induction of genes involved in several physiological processes, including apoptosis, immunity, and inflammation. The binding sites of the NF-kappaB family member p65 were determined by using chromatin immunoprecipitation and a genomic microarray of human chromosome 22 DNA. Sites of binding were observed along the entire chromosome in both coding and noncoding regions, with an enrichment at the 5' end of genes. Strikingly, a significant proportion of binding was seen in intronic regions, demonstrating that transcription factor binding is not restricted to promoter regions. NF-kappaB binding was also found at genes whose expression was regulated by tumor necrosis factor alpha, a known inducer of NF-kappaB-dependent gene expression, as well as adjacent to genes whose expression is not affected by tumor necrosis factor alpha. Many of these latter genes are either known to be activated by NF-kappaB under other conditions or are consistent with NF-kappaB's role in the immune and apoptotic responses. Our results suggest that binding is not restricted to promoter regions and that NF-kappaB binding occurs at a significant number of genes whose expression is not altered, thereby suggesting that binding alone is not sufficient for gene activation.
Corrigendum to: Cytochrome <i>c</i> release and caspase activation in hydrogen peroxide‐ and tributyltin‐induced apoptosis (FEBS 20394) (1998)

The authors wish to inform readers that figures 2C and 3C should be exchanged.
A SiP Tuner with Integrated LC Tracking Filter for both Cable and Terrestrial TV Reception (2007)

A SiP tuner is designed for both terrestrial and cable reception of all analog and digital TV standards. It has 5dB of NF over the 48 to 862MHz frequency band. LC tracking filters allow for achieving 55dB weighted video SNR in loaded spectrum conditions. The active die, implemented in a 40GHz-f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</sub> BiCMOS process, occupies 5.7mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and consumes 750mW.
AUSROC - Australia's Amateur Rocket Program (1992)

A description of the AUSROC Amatuer Rocket Program including past, present and future projects is presented. The objectives and future program goals are discussed along with a basic technical description of the rocket system.
Conformational transition of SARS-CoV-2 spike glycoprotein between its closed and open states (2020)

In 2020, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people worldwide and caused the coronavirus disease 2019 (COVID-19). Spike (S) glycoproteins on the viral membrane bind to ACE2 receptors on the host cell membrane and initiate fusion, and S protein is currently among the primary drug target to inhibit viral entry. The S protein can be in a receptor inaccessible (closed) or accessible (open) state based on down and up positions of its receptor-binding domain (RBD), respectively. However, conformational dynamics and the transition pathway between closed to open states remain unexplored. Here, we performed all-atom molecular dynamics (MD) simulations starting from closed and open states of the S protein trimer in the presence of explicit water and ions. MD simulations showed that RBD forms a higher number of interdomain interactions and exhibits lower mobility in its down position than its up position. MD simulations starting from intermediate conformations between the open and closed states indicated that RBD switches to the up position through a semi-open intermediate that potentially reduces the free energy barrier between the closed and open states. Free energy landscapes were constructed, and a minimum energy pathway connecting the closed and open states was proposed. Because RBD-ACE2 binding is compatible with the semi-open state, but not with the closed state of the S protein, we propose that the formation of the intermediate state is a prerequisite for the host cell recognition.
Averaged large signal model of boost power factor corrector in boundary conduction mode (2009)

A modeling approach of a power factor correction circuit operating in boundary conduction mode is presented. The PFC is controlled by a constant on-time of the switch. The effect of valley switching is simplified and taken into account as dead-time to generate a large signal model. On the basis a small signal model for the constant on-time controlled PFC voltage loop is derived. The large and small signal models are compared to measurements of the transfer function. For performing this low frequency transfer functions measurement a set-up using an oscilloscope and functional generator is described.
Molecular biology of the calcium antagonist receptor. (1992)

The calcium channel plays a key role in controlling many physiological processes in the body. Drugs that block the calcium channel have proven clinically effective for the treatment of a multitude of cardiovascular disorders. The elucidation of the precise mechanism of action of these drugs involves cloning the calcium channels on which they act. Genetic manipulation of these cloned channels is beginning to reveal the binding sites for the calcium channel blocking drugs and may lead to the development of more specific agents.
AN ANALYSIS OF THE CURRENT AND FUTURE STATE OF 3D FACIAL ANIMATION TECHNIQUES AND SYSTEMS (2009)

Computer facial animation is now being used in a multitude of important fields. It brings a more human, social and dramatic reality to computer games, films and interactive multimedia, and is growing in use and importance. Authoring computer facial animation with complex and subtle expressions is still difficult and fraught with problems. It is currently mostly authored using generalized computer animation techniques, which often limit the quality and quantity of facial animation production. Given additional computer power, facial understanding and software sophistication, new face-centric methods are emerging but typically are immature in nature. This research attempts to define and organizationally categorize current and emerging methods, including surveying facial animation experts to define the current state of the field, perceived bottlenecks and emerging techniques. The thesis culminates in documenting this shared knowledge and making recommendations based on the data gathered, on possible new techniques for next generation, face-centric, computer animation systems.
Contrast enhancement of the brownish horseradish peroxidase-activated 3,3'-diaminobenzidine tetrahydrochloride reaction product in black and white photomicrography by the use of interference filters. (1984)

An interference filter combination for contrast enhancement of the brownish, peroxidase-activated, 3,3'-diaminobenzidine tetrahydrochloride reaction product has been developed. This filter combination allows transmission of light in two narrow bands, representing those of the primary colors green (480-500 nm) and red (575-585 nm) as well as a broader band between 385-430 nm. The visual contrast enhancement of horseradish peroxidase-containing neurons caused by the interference filters was excellent. In particular, intracellular details were prominent in the presence of the interference filters compared with different blue absorption filters. The contrast enhancement was evaluated by microdensitometry of an Agfapan 25 emulsion onto which peroxidase-containing neurons in noncounterstained sections were exposed. The microdensitometry showed a neuron to background contrast enhancement of 30% compared to neutral gray filters and of 11% compared to a Kodak Wratten 80A blue absorption filter. The interference filters are available from the Laboratory of Technical Optics, the Technical University of Copenhagen, Building 307, Lundtoftevej 100, DK-2800 Lyngby, Denmark (order: DAB-interference filters, 30 mm). The interference filter principle can be used for contrast enhancement of other compound colors.
Phosphatidic Acid Regulates Tyrosine Phosphorylating Activity in Human Neutrophils (2001)

In human neutrophils, the activation of phospholipase D and the Tyr phosphorylation of proteins are early signaling events upon cell stimulation. We found that the pretreatment of neutrophils with ethanol (0.8%) or 1-butanol (0.3%), which results in the accumulation of phosphatidylalcohol at the expense of phosphatidic acid (PA), decreased the phorbol myristate acetate-stimulated Tyr phosphorylation of endogenous proteins (42, 115 kDa). When neutrophil cytosol was incubated in the presence or absence of PA, these and other endogenous proteins became Tyr-phosphorylated in a PA-dependent manner. In contrast, phosphatidylalcohols exhibited only 25% (phosphatidylethanol) or 5% (phosphatidylbutanol) of the ability of PA to stimulate Tyr phosphorylation in the cell-free assay. Similarly, other phospholipids (phosphatidylcholine, phosphatidylethanolamine, phosphatidylglycerol, phosphatidylserine, phosphatidylinositol, polyphosphoinositides, and sphingosine 1-phosphate) showed little ability to stimulate Tyr phosphorylation. These data suggest that PA can function as an intracellular regulator of Tyr phosphorylating activity. Gel filtration chromatography of leukocyte cytosol revealed a peak of PA-dependent Tyr phosphorylating activity distinct from a previously described PA-dependent phosphorylating activity (Waite, K. A., Wallin, R., Qualliotine-Mann, D., and McPhail, L. C. (1997) J. Biol. Chem. 272, 15569-15578). Among the protein Tyr kinases expressed in neutrophils, only Fgr eluted exclusively in the peak of PA-dependent Tyr phosphorylating activity. Importantly, Fgr isolated from unstimulated neutrophil lysates showed increased activity in the presence of PA but not phosphatidylbutanol. Moreover, the pretreatment of neutrophils with 1-butanol decreased Fgr activity in cells stimulated with formyl-methionyl-leucyl phenylalanine plus dihydrocytochalasin B. Together, these results suggest a new second messenger role for PA in the regulation of Tyr phosphorylation.
Application of vibration signal in the diagnosis of IC engine valve clearance (2015)

The article describes a concept of a non-invasive method for diagnosing the size of valve clearance in internal combustion engines, based on the analysis of engine surface vibration signals using artificial neural networks. The applicability of the method was tested on a single-cylinder compression-ignition engine with a low power rating, which had an OHV timing gear, acting indirectly on the valves, and manual adjustment of valve clearance. The method uses as diagnostic signals the readings of vibration sensors, which record the acceleration of engine head movement as a function of the angle of rotation of the crankshaft, with pre-set valve clearance values measured in a cold condition. From among the signals recorded, components corresponding to the impact of rocker arms against valve stems were identified and low-pass filtered in order to eliminate measurement interference. A classifier of selected features of the signals processed was constructed using artificial neural networks. This classifier recognizes signals generated by engines with correct valve clearance as well as those with too much and too little valve clearance.