gebhart/patrepeval huggingface dataset:
MaxMinOver: a simple incremental learning procedure for support vector classification (2004)

The well-known MinOver algorithm is a simple modification of the perceptron algorithm and provides the maximum margin classifier in a linearly separable two class classification problem. In its dual formulation selected training patterns which determine the separating hyperplane have to be stored. A drawback of MinOver is that this set of patterns does not consist only of support vectors. With MaxMinOver an extension of MinOver by a simple forgetting procedure is introduced. It is shown that this forgetting not only reduces the number of patterns which have to be stored, but also improves convergence bounds. After a finite number of training steps, the set of stored training patterns will consist only of support vectors. It is shown how this simple and iterative procedure can also be extended to classification with soft margins. The SoftMaxMinOver algorithm exhibits close connections to the v/support-vector-machine.
Design of molecules which specifically cleave abasic sites in DNA. (1990)

In order to understand the mechanism of DNA breakage at apurinic/apyrimidinic (AP) sites and «modulate» this activity, we have prepared a series of analogs in which we successively changed the nature of the intercalating moiety, of the nucleic base and of the linking chain. In this communication, we wish to report the synthesis of analogs that have been qualitatively tested for their ability to induce DNA breakage at AP sites
CEnT: An Efficient Architecture to Eliminate Intra-Array Write Disturbance in PCM (2021)

Phase Change Memory (PCM), with its better scaling potential compared to DRAM, is seen as a promising candidate to replace or complement DRAM. The heat generated from a RESET programming pulse to a PCM cell can disturb the neighboring cells which are not being programmed. Write disturbance (WD) poses a critical reliability challenge in high-density PCM memory with scaling below 20nm process technology node. Increasing the intra-cell space can eliminate the WD, however, it reduces the storage density which counteracts the benefits of scalability in PCM. At architectural level, a verify and correct (VnC) technique can be used to address this problem. However, this leads to an increased number of write operations, thus degrading performance, energy efficiency and memory lifetime. Due to its dependence on the type of programming operation and the state of the neighboring cell, WD is a data-dependent problem. Exploiting this property, encoding techniques have been proposed to reduce the frequency of WD-vulnerable data patterns. These techniques, however, do not eliminate the WD in an array and ultimately rely on the VnC method to ensure reliable memory operation. This article introduces a novel architecture, based on encoding and multi-level programming characteristics of PCM, to eliminate the intra-array WD in PCM. By eliminating WD and hence the need for a VnC operation, the proposed architecture improves performance, energy efficiency and memory lifetime. Our evaluation of the proposed architecture shows an average reduction of 57 percent in the number of writes (to service one write request) over the existing state-of-the-art intra-array WD-mitigation technique. Depending on the PCM write bandwidth, the proposed architecture can reduce the write service time by up to 27 percent, on average, compared to the existing best-performing technique. This leads to an average improvement of 15 percent in IPC. Additionally, by eliminating the overhead of a verify operation, the write energy efficiency is also improved by 8 percent over the previous art. Finally, with an average reduction of 26 percent in bit flips, the proposed method also improves the memory lifetime. The proposed method is also proven to be effective when considering WD both within the word-lines and across the bit-lines.
The History of the Alien Priory of Wenlock (1939)

(1939). The History of the Alien Priory of Wenlock. Journal of the British Archaeological Association: Vol. 4, No. 1, pp. 117-140.
A Comparison of Methods for Predicting Gaseous Diffusion Coefficients (1965)

Nine methods for the estimation of gaseous diffusion coefficients in gas chromatography are reviewed. In order to demonstrate the relative reliability of the various methods a comparison has been made using experimental data from recent sources. Recommendations are given to assist in making the most suitable choice of methods to be employed under a variety of circumstances.
The Biological Activity of Vinyl and Butenyl Sulfone Derivatives (1971)

Abstract Mono‐ and bifunctional amino‐ and quaternary ammonium derivatives of ethyl‐ and butenylsulfones have been prepared, and preliminary results on their biological activity are reported.
: Musique Fantastique: A Survey of Film Music in the Fantastic Cinema . Randall D. Larson. (1986)

Book Review| July 01 1986 Review: Musique Fantastique: A Survey of Film Music in the Fantastic Cinema by Randall D. Larson Musique Fantastique: A Survey of Film Music in the Fantastic CinemaRandall D. Larson Ross Care Ross Care Search for other works by this author on: This Site PubMed Google Scholar Film Quarterly (1986) 39 (4): 46–47. https://doi.org/10.2307/1212497 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Ross Care; Review: Musique Fantastique: A Survey of Film Music in the Fantastic Cinema by Randall D. Larson. Film Quarterly 1 July 1986; 39 (4): 46–47. doi: https://doi.org/10.2307/1212497 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentFilm Quarterly Search This content is only available via PDF. Copyright 1986 The Regents of the University of California Article PDF first page preview Close Modal You do not currently have access to this content.
Biological control of aflatoxins in Africa: current status and potential challenges in the face of climate change (2016)

Aflatoxin contamination of crops is frequent in warm regions across the globe, including large areas in sub-Saharan Africa. Crop contamination with these dangerous toxins transcends health, food security, and trade sectors. It cuts across the value chain, affecting farmers, traders, markets, and finally consumers. Diverse fungi within Aspergillus section Flavi contaminate crops with aflatoxins. Within these Aspergillus communities, several genotypes are not capable of producing aflatoxins (atoxigenic). Carefully selected atoxigenic genotypes in biological control (biocontrol) formulations efficiently reduce aflatoxin contamination of crops when applied prior to flowering in the field. This safe and environmentally friendly, effective technology was pioneered in the US, where well over a million acres of susceptible crops are treated annually. The technology has been improved for use in sub-Saharan Africa, where efforts are under way to develop biocontrol products, under the trade name Aflasafe, for 11 African nations. The number of participating nations is expected to increase. In parallel, state of the art technology has been developed for large-scale inexpensive manufacture of Aflasafe products under the conditions present in many African nations. Results to date indicate that all Aflasafe products, registered and under experimental use, reduce aflatoxin concentrations in treated crops by >80% in comparison to untreated crops in both field and storage conditions. Benefits of aflatoxin biocontrol technologies are discussed along with potential challenges, including climate change, likely to be faced during the scaling-up of Aflasafe products. Lastly, we respond to several apprehensions expressed in the literature about the use of atoxigenic genotypes in biocontrol formulations. These responses relate to the following apprehensions: sorghum as carrier, distribution costs, aflatoxin-conscious markets, efficacy during drought, post-harvest benefits, risk of allergies and/or aspergillosis, influence of Aflasafe on other mycotoxins and on soil microenvironment, dynamics of Aspergillus genotypes, and recombination between atoxigenic and toxigenic genotypes in natural conditions.
Sparse matrix methods for chemical process separation calculations on supercomputers (1992)

The author considers using the frontal method on supercomputers to solve the large, sparse linear equation systems arising in process separation calculations. The motivation is that the frontal method takes advantage of vector computers by treating parts of the sparse matrix as full submatrices. This allows arithmetic operations to be performed with full-matrix code and circumvents the difficulties inherent in indirect addressing on vector processors. Separation problems from the commercial simulators ASPEN PLUS and SPEEDUP are used as test cases. Results on a CRAY Y-MP supercomputer show that the frontal method significantly reduces simulation time, by more than an order of magnitude in many cases, compared to traditional sparse matrix methods. >
A portable machine-independent global optimizer--design and measurements (1984)

This dissertation addresses the topic of portable and machine-independent program optimization on a standard, well-defined intermediate code. The design of the intermediate code, and features needed to support machine-independent optimization are discussed. A number of new techniques in program optimization are presented. These techniques when applied can substantially reduce both the implementation complexities and running time of optimizers in general, with no sacrifice in the optimizations performed. A register allocation algorithm based on node coloring, suitable for use in the machine-independent context, is introduced. An implementation of these techniques in the machine-independent optimizer UOPT is presented. The optimization performance, efficiency and the relative importance among the different types of optimization transformations are studied according to timing measurements, optimization statistics and by variation in optimization parameters. Finally, the effectiveness of portable machine-independent optimization on a number of target machines that support the intermediate code is discussed, based on optimization performance data in the different machines and comparisons of machine characteristics. The overall evaluation confirms the advantages of using portable machine-independent optimization in a retargetable compiler system.
Age differences in summarizing descriptive and procedural texts (1993)

This study compared young and older adults' summaries of expository texts under the hypothesis that older adults would be more experienced, hence more accurate, at summarizing texts. Two types of expository texts were used: procedural and descriptive texts. The texts were read by a panel of judges who wrote summaries of each text and identified the central ideas of each text; the judges' summaries were used to prepare lists of the central ideas of each text and to write standard summaries of each text. The participants read four texts, two orally and two silently, and then wrote summaries, which were limited to 50 words. Words-per-minute reading times were collected and the summaries were scored on two measures of content, how many ideas were reproduced from the original texts and the proportion of central ideas that were reproduced, and two measures of length, the number of sentences and the number of words. Although the older adults read more slowly than the young adults, the older adults reproduced more total and central ideas than the young ideas.
Bring back the 'gig' to Australian law enforcement: Human source developments (2012)

The arguments for and against the use of informants, now known as human sources, in law enforcement practice is not a new debate. Australian law enforcement agencies, like many of their international counterparts have experienced decades of change in the movement toward and away from the use of human sources in criminal investigations and the intelligence gathering process. In this article, some of the reasons for this inertia are explored within the context of historical changes in the Australian law enforcement landscape. In this study, in-depth interviews were conducted with seven Australian policing and intelligence agencies with senior management and operational police officers working at recruiting and handling informants. Analysed transcripts from key agency representative interviews identified core themes on the historical political, regulatory systems and social drivers exerting influence on Australian human source management including the more recent trends in the resurgence of informant management practices. A secondary source review and analysis of current and past Australian law enforcement policies and internal reports was also undertaken as part of the methodology applied in this study. As part of good reporting practice for ensuring confidentiality and agency anonymity is maintained, sensitive and operational information has been sanitised from the themes reported in this article. This paper will argue that a great deal of work continues to be done across our Australian Law enforcement agencies in terms of broadening the present day focus in both the 'notional type' of who is considered a human source, how human sources are deployed and the expanding on the expertise and training for those working with human sources.
Synchronous dynamic focusing for ultrasound imaging (1988)

An approach to dynamic focusing of ultrasound linear array scanners is presented, leading to the unique capability of implementing a focus that continuously tracks the return signal along the penetration depth. An electronically variable lens is obtained by a heterodyning process, in which the phases of echo signals at the array elements are equalized by mixing with suitable reference oscillations. These are generated by control of a single voltage-controlled oscillator, whose frequency is properly varied in synchronism with the delay of signal from different depths. The technique has been experimentally demonstrated by modifying the focusing processor of a conventional echographic linear scanner. Superior performances have been obtained with respect to fixed-focus operation mode. The image quality results are comparable with those of multizone-focus operation mode, in which the focus is varied over more transmit/receive cycles at the expense of lower frame rate.
Alignment Mechanism of Nematic Liquid Crystal on Rubbed Polymer Surface Studied by Subsequent Processes of Rubbing and Photoalignment (2000)

A novel method for understanding the alignment mechanism was motivated by the texture observation of a nematic liquid crystal (LC) contacted with a photoaligned layer after rubbing. Reorientation of director occurs by subsequent photoalignment to different direction from that forced by rubbing. Moreover, it was found by polarized absorption spectra that the preferential average main chain axis over whole the alignment layer does not change, indicating that the orientation change by photoalignment occurs only at very top surfaces. This experiment without changing surface morphology indicates that the alignment priority for the nematic LC is mainly governed by the anisotropic short-range intermolecular interaction between alignment films and LC molecules and the effect of microgrooves plays a minor role.
Tensin1 Requires Protein Phosphatase-1α in Addition to RhoGAP DLC-1 to Control Cell Polarization, Migration, and Invasion (2009)

Tensin is a family of multidomain scaffold proteins that bind the cytoplasmic tail of beta-integrins and localize to adhesions that anchor stress fibers in cells. Tensin expression is suppressed in cancer, especially metastatic cancer. The N-terminal domain of tensin1 associates with protein phosphatase-1alpha (PP1alpha) and mediates PP1alpha localization to adhesions. Here, we show F302A mutation in a KVXF motif of tensin1 abrogates binding to PP1alpha. The SH2 domain in tensin family member c-ten requires R474 to bind a RhoGAP called DLC-1 (deleted in liver cancer). We mutated the corresponding residue in tensin1, R1488A, and showed this reduces association with DLC-1. Unexpectedly, tensin1 F302A also had reduced association with DLC-1. Expression of tensin1 F302A or R1488A showed similar dominant phenotypes, with reduced cell polarization, lowered MLC20 phosphorylation and reduced levels of RhoA(GTP) compared with cells expressing tensin1 WT. However, migration and invasion of metastatic MDA MB 231 breast cancer cells were differentially affected by tensin1 mutated at F302A or R1488A. Cancer cells stably expressing F302A tensin1 showed increased migration and invasion compared with cells stably expressing either R1488A tensin1 or WT tensin1. This suggests that PP1alpha bound to tensin1 has additional effects in reducing migration and invasion that are not mediated through DLC-1. Our results show the importance of PP1alpha binding to tensin1 for the regulation of cell polarization, migration, and invasion.
Multiple reflection and attenuation of time domain reflectometry pulses: Theoretical considerations for applications to soil and water (1988)

The application of time domain reflectometry (TDR) to determine soil water content, using only the time axis of a TDR trace, has been widely investigated. Other interpretations from the TDR trace, such as the determination of electrical conductivity, make use of the amplitude or reflection coefficient values. These latter interpretations must take account of multiple reflections in the media. A multiple‐reflection algorithm is developed which takes account of primary reflection first, then provides for inclusion of higher‐order reflections as well. The algorithm is formulated to generate the TDR trace from a sequence of known dielectrics. The inverse case is analyzed where the dielectric constant of the layered medium is calculated from a measured TDR trace. The model allows for both conductive and nonconductive dielectrics. Experiments showed that the model is a reasonably good qualitative representation of the layered nonconductive media with a wide range of dielectric constants. There is insufficient information in a TDR trace to solve the conductive cases except for a single layer. From KCl solutions at two concentrations the experiments showed that instantaneous reflection and transmission are inadequate assumptions for conductive systems. This indicates the need for caution when applying the model to conductive media such as soils, especially where soil water content is not uniform.
Penile rehabilitation after radical prostatectomy: does it work? (2015)

Although preclinical evidences support the rationale for penile rehabilitation after nerve-sparing RP, clinical studies reported conflicting results regarding its efficacy on long-term EF recovery. Nowadays, which is the optimal rehabilitation program still represents a matter of debate.
Effects of extracellular matrix on the growth and casein gene expression of primary mouse mammary tumor cells in vitro. (1989)

This study describes a serum-free culture system and provides a tumor model to investigate the effects of extracellular matrices on the growth and beta-casein gene expression of mouse mammary tumor epithelial cells (MMTCs) in vitro. Primary cultures of MMTCs derived from autochthonous mammary tumors in BALB/cfC3H x DBA/8 F1 mice, FUKU cells, an established MMTC line, and COMMA-1D cells established from mouse mammary tissues were studied. A reconstituted basement membrane from the Englbreth-Holm-Swarm tumor (Matrigel) allowed a 2.7-fold increase in cell number of 5-day primary MMTC cultures in serum-free, insulin-supplemented medium. FUKU and COMMA-1D cells in serum-free medium displayed a 13.6- and 11.5-fold increase in cell number, respectively, after 5 and 6 days in culture on Matrigel. In semisolid agar cultures, Matrigel or laminin was shown to promote colony-forming efficiency of FUKU cells when either of the matrices was mixed in the top agar layer. An increase of 4.4 or 2.1 times in colony-forming efficiency was detected when 20% (v/v) Matrigel or 112 micrograms/ml of laminin were mixed in the agar layer compared with FUKU cells plated in plain agar. beta-Casein mRNA was detectable by Northern blot assays in the primary mammary tumors. MMTCs in primary cultures grown on Matrigel in serum-free, insulin-supplemented medium for 4 days were inducible for beta-casein mRNA following the treatment with prolactin and hydrocortisone (FPRL) for 24 h. No beta-casein mRNA was detectable in the absence of FPRL. MMTCs in the primary cultures could also be induced for beta-casein mRNA when they were cultivated on type I collagen gels for 4 days but not on laminin, type IV collagen, or plastic. However, the capacity to respond to FPRL was not lost in MMTCs cultured on laminin. When MMTCs were initially cultured on laminin for 4 days and then subcultured on Matrigel for another 4 days, they were inducible for beta-casein mRNA upon exposure to FPRL for 24 h. In contrast, no beta-casein mRNA upon exposure to FPRL for 24 h. In contrast, no beta-casein mRNA was found in MMTCs from the same tumors cultured on laminin for 8 days with the same treatment of hormones. These data demonstrate that cells from autochthonous mammary tumors, which are not dependent on estrogen for growth in vivo, are inducible in vitro for beta-casein mRNA by FPRL; and this hormonal response of MMCTs requires appropriate extracellular matrix.
Functional studies of truncated soluble intercellular adhesion molecule 1 expressed in Escherichia coli (1993)

We have expressed in Escherichia coli the two N-terminal immunoglobulin (Ig)-like domains of the intercellular adhesion molecule 1 (ICAM-1). The first 188 residues of ICAM-1 were expressed with an N-terminal methionine (MP188) or as a maltose-binding fusion protein which was cleaved with factor Xa (XP188). After refolding, both MP188 and XP188 were active in binding to the leukocyte integrin lymphocyte function-associated antigen 1, which has previously been shown to bind to the N-terminal Ig domain of ICAM-1. The major group of rhinoviruses and malaria-infected erythrocytes bind to distinct sites within the first Ig-like domain of ICAM-1. Both MP188 and XP188 bound to malaria-infected erythrocytes; however, only XP188 inhibited human rhinovirus plaque formation. A product (MdQ1P188) with the initiation methionine fused to residue 2, i.e., with glutamine 1 deleted, inhibited plaque formation. MdQ1P188 was able to induce a conformational change of the virus capsid as shown by conversion of 149S particles to 85S particles, whereas MP188 had no effect. These results show that functionally active fragments of ICAM-1 can be produced in E. coli, that glycosylation is not required for ligand binding, and that the N-terminal residue of ICAM-1 is proximal to or part of the human rhinovirus-binding site.
WORM vs. WORM (2004)

Self-propagating computer worms have been terrorizing the Internet for the last several years. With the increasing density, inter-connectivity and bandwidth of the Internet combined with security measures that inadequately scale, worms will continue to plague the Internet community. Existing anti-virus and intrusion detection systems are clearly inadequate to defend against many recent fast-spreading worms. In this paper we explore an active counter-attack method - anti-worms. We propose a method that transforms a malicious worm into an anti-worm which disinfects its original. The method is evaluated using the CodeRed, Blaster and Slammer worms. We show through simulation the effectiveness of an anti-worm with several propagation schemes and its impact on the overall network. We also discuss important limitations of the proposed method.