gebhart/patrepeval huggingface dataset:
Cerium(III) Sulfide and Selenide and Some of their Solid Solutions<sup>1</sup> (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCerium(III) Sulfide and Selenide and Some of their Solid Solutions1E. Banks, K. F. Stripp, H. W. Newkirk, and R. WardCite this: J. Am. Chem. Soc. 1952, 74, 10, 2450–2453Publication Date (Print):May 1, 1952Publication History Published online1 May 2002Published inissue 1 May 1952https://pubs.acs.org/doi/10.1021/ja01130a002https://doi.org/10.1021/ja01130a002research-articleACS PublicationsRequest reuse permissionsArticle Views365Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A method to estimate the somatic cell count of milk from a mastitic quarter using composite somatic cell count. (1990)

The purpose of the study was to estimate the extent to which one quarter could be inflamed relative to the other three quarters of a cow, given that knowledge only of the composite milk somatic cell count (SCC) was available. An algebraic relationship, which incorporated the parameters of composite milk SCC, production loss associated with composite milk SSC, SCC of milk from an inflamed quarter, and SCC from three non-inflamed quarters, was used to derive hypothetical estimates of the SCC in one inflamed quarter. A simple case was considered in which one quarter was mastitic, the SCC in milk of the noninflamed quarters was equal, and there was no production compensation by the noninflamed quarters. Previously published estimates were used for production loss associated with composite milk SCC. For moderate composite milk SCC (300,000-500,000 cells/mL) and low-to-moderate SCC in milk of noninflamed quarters (100,000 cells/mL), the SCC of milk from one inflamed quarter was predicted to be very high, ranging from about 1.26 million (log10 SCC = 6.1) to 6.3 million (log10 SCC = 6.8) cells/mL, and compatible with signs of clinical mastitis. These results suggest that in order to screen cows with clinical mastitis in only one quarter, composite milk SCC should be considerably lower than values presented previously by other investigators.
Parvoviral virions deploy a capsid-tethered lipolytic enzyme to breach the endosomal membrane during cell entry (2005)

Enveloped viruses deliver their virions into the host cell by fusion with the cellular plasma or endosomal membrane, thus creating topological continuity between the cytosol and the inside of the viral envelope. Nonenveloped viruses are, by their very nature, denied this strategy and must employ alternative methods to breach their host cell's delimiting membrane. We show here that the compact icosahedral parvoviral virion gains entry by deploying a lipolytic enzyme, phospholipase A(2) (PLA(2)), that is expressed at the N terminus of VP1, the minor coat protein. This region of VP1 is normally sequestered within the viral shell but is extruded during the entry process as a capsid-tethered domain. A single amino acid substitution in the active site of the VP1 PLA(2) inactivates enzymatic activity and abrogates infectivity. We have used transencapsidation of a vector expressing green fluorescent protein to show that infection by this PLA(2)-defective mutant can be complemented by coinfection with wild-type or mutant full virions, provided they can express a functional PLA(2). Even though wild-type empty capsids contain an active form of the enzyme, it is not externalized under physiological conditions, and such capsids are not able to complement the PLA(2) mutant. Significantly, highly efficient rescue can be achieved by polyethyleneimine-induced endosome rupture or by coinfection with adenovirus as long as uptake of the two viruses is simultaneous and the adenovirus is capable of deploying pVI, a capsid protein with endosomolytic activity. Together, these results demonstrate a previously unrecognized enzymatic mechanism for nonenveloped virus penetration.
Why Prefer Double Robust Estimates? Illustration with Causal Point Treatment Studies (2002)

In point treatment marginal structural models with treatment A, outcome Y and covariates W, causal parameters can be estimated under the assumption of no unobserved confounders. Three estimates can be used: the G-computation, Inverse Probability of Treatment Weighted (IPTW) or Double Robust (DR) estimates. The properties of the IPTW and DR estimates are known under an assumption on the treatment mechanism that we name "Experimental Treatment Assignment" (ETA) assumption. We show that the DR estimating function is unbiased when the ETA assumption is violated if the model used to regress Y on A and W is correctly specified. The practical consequence is that the IPTW estimate is biased at finite sample size when the ETA assumption is approximately or theoretically violated, whereas the finite sample bias for the DR estimate is negligible if the model used to regress Y on A and W is correctly specified. This result also implies that estimating point treatment causal parameters using a DR estimating function is more robust than using the G-computation formula. We conclude with a methodology to construct DR estimates for a general data structure and prove that such DR estimates are more robust than their corresponding maximum likelihood estimates.
The control system research of paving machine for the modified asphalt coiled material (2011)

The modified asphalt coiled material is widely used as waterproofs in the construction of highway, railway and other engineering. The asphalt is usually paved by manual work. The quality of paving is easily affected by conditions such as the weather and the worker's skill. However the working condition is very bad for the paving worker. It is necessary to research a paving machine in order to improve the paving quality and working conditions. A new paving machine for the modified asphalt coiled material is designed in this paper. Some anti-interference measures were adopted in order to adapt the bad environments. For example, PLC is used as the controller, AC servo motor and stepping motor is used as executive component. Photoelectrical coupling is used in circuit connection. This new paving machine two controls modes. One is manual control mode. The other is automatic mode. The worker controls the paving machine through operate the control panel in manual mode. The PLC control the direction and speed of the machine in the automatic mode with the photosensor seek the position of ground markers and send the signal to PLC. The proportional controlling means and the backlash compensation were adopted in this paper in order to achieve accuracy control. After numerous experiments, the paving machine can adapt to the construction requirements.
P‐glycoprotein inhibition promotes prednisone retention in human sinonasal polyp explants (2014)

Background P‐glycoprotein (P‐gp) is an efflux pump, which is part of the innate chemo‐immunity defense system and is overexpressed in chronic rhinosinusitis with nasal polyps (CRSwNP). P‐gp is capable of regulating corticosteroid retention and thus P‐gp upregulation has been implicated in steroid resistance in several inflammatory disorders. The goal of this study is to determine whether P‐gp regulates intracellular steroid retention in CRSwNP. Methods This was a Massachusetts Eye and Ear Infirmary Institutional Review Board (IRB)‐approved study in nasal polyp explants. Polyps were exposed to 50 μg/mL of prednisone for 30 minutes with or without the presence of a P‐gp inhibitor (Verapamil 12.5 μM or Zosuquidar 0.31 μM) followed by a 40‐minute washout period (n = 16 per group). Intracellular steroid retention was determined by quantifying the concentration of both intracytoplasmic and secreted steroid using an enzyme‐linked immunosorbent assay (ELISA). Concentrations relative to control were compared using a Student t test. Results The intracytoplasmic prednisone concentration was significantly greater relative to control following P‐gp inhibition with Verapamil (155.28% ± 22.48%, p < 0.05) and Zosuquidar (125.81% ± 12.41%, p < 0.05). Similarly, the amount of prednisone secreted by the explant was significantly reduced at 30 minutes following P‐gp inhibition with Zosuquidar (78.64% ± 2.98%, p < 0.05) and 40 minutes following P‐gp inhibition with Verapamil (80.56% ± 5.02%, p < 0.05). Conclusion Inhibition of P‐gp enhances the intracellular accumulation of prednisone in nasal polyps. This suggests that P‐gp participates in regulation of glucocorticoid retention in sinonasal mucosa. These findings, coupled with the known overexpression of P‐gp in CRSwNP, may point to a possible mechanism for steroid resistance in this patient population.
Dynamic control of bipeds using postural adjustment strategy (2002)

In this paper, we propose a new way to solve the dynamic control of a humanoid biped robot in an unknown environment, taking into account the postural adjustment. For that a multichain mechanical model of a human body (called BIPMAN) is proposed with a general control architecture. We use the postural adjustment notion (physiological notion) to ensure the biped dynamic equilibrium. The principle is based on behavioral rules using limiting conditions and "equilibrium classes". This notion is introduced at the "coordinator level" of our architecture and more especially in RTCA technique development (real-time contraints adaptation). This technique is based on a general criterion which is able to minimize roll and pitch angles in function of the task constraints (bipodal or unipodal posture). Finally, we illustrate the whole strategy through examples.
Analysis of Synthetic Anionic Detergent Compositions (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalysis of Synthetic Anionic Detergent CompositionsRalph. House and J. L. DarraghCite this: Anal. Chem. 1954, 26, 9, 1492–1497Publication Date (Print):September 1, 1954Publication History Published online1 May 2002Published inissue 1 September 1954https://pubs.acs.org/doi/10.1021/ac60093a025https://doi.org/10.1021/ac60093a025research-articleACS PublicationsRequest reuse permissionsArticle Views247Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Parallel Anisotropic Block-based Adaptive Mesh Refinement Finite-volume Scheme (2012)

A novel parallel block-based anisotropic adaptive mesh refinement (AMR) technique for multi-block body-fitted grids is proposed and described. Rather than adopting the more usual isotropic approach to mesh refinement, an anisotropic refinement procedure is proposed which allows refinement of grid blocks in each coordinate direction in an independent fashion. This allows for more efficient and accurate treatment of narrow layers and/or discontinuities which occur, for example, in the boundary and mixing layers of viscous flows, and in regions of strong non-linear wave interactions with shocks. The anisotropic AMR technique is implemented within an existing finite-volume framework, which encompasses both explicit and implicit solution methods, and is capable of performing calculations with second- and higher-order spatial accuracy. To clearly demonstrate the feasibility of the proposed technique, it is applied to the unsteady and steady-state solutions of both the advection diffusion equation, as well as the Euler equations, in two space dimensions.
Diamond-Like Carbon Film Deposition Using DC Ion Source with Cold Hollow Cathode (2014)

Carbon diamond-like thin films on a silicon substrate were deposited by direct reactive ion beam method with an ion source based on Penning direct-current discharge system with cold hollow cathode. Deposition was performed under various conditions. The pressure (12–200 mPa) and the plasma-forming gas composition consisting of different organic compounds and hydrogen (C 3 H 8 , CH 4 , Si(CH 3 ) 2 Cl 2 , H 2 ), the voltage of accelerating gap in the range 0.5–5 kV, and the substrate temperature in the range 20–850°C were varied. Synthesized films were researched using nanoindentation, Raman, and FTIR spectroscopy methods. Analysis of the experimental results was made in accordance with a developed model describing processes of growth of the amorphous and crystalline carbon materials.
An In-depth Study of Stochastic Kronecker Graphs (2011)

Graph analysis is playing an increasingly important role in science and industry. Due to numerous limitations in sharing real-world graphs, models for generating massive graphs are critical for developing better algorithms. In this paper, we analyze the stochastic Kronecker graph model (SKG), which is the foundation of the Graph500 supercomputer benchmark due to its many favorable properties and easy parallelization. Our goal is to provide a deeper understanding of the parameters and properties of this model so that its functionality as a benchmark is increased. We develop a rigorous mathematical analysis that shows this model cannot generate a power-law distribution or even a lognormal distribution. However, we formalize an enhanced version of the SKG model that uses random noise for smoothing. We prove both in theory and in practice that this enhancement leads to a lognormal distribution. Additionally, we provide a precise analysis of isolated vertices, showing that graphs that are produced by SKG might be quite different than intended. For example, between 50% and 75% of the vertices in the Graph500 benchmarks will be isolated. Finally, we show that this model tends to produce extremely small core numbers (compared to most social networks and other real graphs) for common parameter choices.
Fasting plasma free fatty acid concentrations and Pro12Ala polymorphism of the peroxisome proliferator‐activated receptor (PPAR) γ2 gene in healthy individuals (2002)

This study does not show any relationship between the Pro12Ala polymorphism of the PPARgamma gene and fasting FFAs in the general population. The possibility of a different handling of FFAs under different conditions (i.e. postprandial) cannot be excluded and remains to be explored.
Acidity of Biomass Fast Pyrolysis Bio-oils (2010)

The use of the total acid number (TAN) method for measuring the acidity of biomass fast pyrolysis bio-oil was evaluated. Suggestions for carrying out the analysis have been made. The TAN method by American Society for Testing and Materials (ASTM) D664 or D3339 can be used for measuring the acidity of fast pyrolysis bio-oils and their hydrotreating products. The main difference between the methods is that ASTM D664 is specified for higher TAN values than ASTM D3339. Special focus should be placed on the interpretation of the TAN curves because they differ significantly from those of mineral oils. The curve for bio-oils is so gentle that the automatic detection may not observe the end point properly, and derivatization should be used. The acidity of fast pyrolysis bio-oils is mainly derived (60−70%) from volatile acids. Other groups of compounds in fast pyrolysis bio-oils that influence acidity include phenolics, fatty and resin acids, and hydroxy acids.
Selective anxiolysis produced by ocinaplon, a GABA <sub>A</sub> receptor modulator (2005)

Benzodiazepines remain widely used for the treatment of anxiety disorders despite prominent, often limiting side effects including sedation, muscle relaxation, and ataxia. A compound producing a robust anxiolytic action comparable to benzodiazepines, but lacking these limiting side effects at therapeutic doses (an anxioselective agent), would represent an important advance in the treatment of generalized anxiety disorder, and perhaps other anxiety disorders. Here we report that the pyrazolo[1,5-a]-pyrimidine, ocinaplon, exhibits an anxioselective profile in both preclinical procedures and in patients with generalized anxiety disorder, the most common of the anxiety disorders. In rats, ocinaplon produces significant muscle relaxation, ataxia, and sedation only at doses >25-fold higher than the minimum effective dose (3.1 mg/kg) in the Vogel "conflict" test. This anticonflict effect is blocked by flumazenil (Ro 15-1788), indicating that like benzodiazepines, ocinaplon produces an anxiolytic action through allosteric modulation of GABA(A) receptors. Nonetheless, in eight recombinant GABA(A) receptor isoforms expressed in Xenopus oocytes, the potency and efficacy of ocinaplon to potentiate GABA responses varied with subunit composition not only in an absolute sense, but also relative to the prototypical benzodiazepine, diazepam. In a double blind, placebo controlled clinical trial, a 2-week regimen of ocinaplon (total daily dose of 180-240 mg) produced statistically significant reductions in the Hamilton rating scale for anxiety scores. In this study, the incidence of benzodiazepine-like side effects (e.g., sedation, dizziness) in ocinaplon-treated patients did not differ from placebo. These findings indicate that ocinaplon represents a unique approach both for the treatment and understanding of anxiety disorders.
A PKI study within the educational environment (2011)

This paper presents our current effort in building a public-key infrastructure supporting security services within our university. Digital certificates are meant to provide authentication and confidentiality for entities engaging in electronic transactions, and flexible access control management for administrators of IT services.
An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of Hand Foot and Mouth Disease in Fuyang city of China (2010)

Hand, foot and mouth disease (HFMD), a common contagious disease that usually affects children, is normally mild but can have life-threatening manifestations. It can be caused by enteroviruses, particularly Coxsackieviruses and human enterovirus 71 (HEV71) with highly variable clinical manifestations. In the spring of 2008, a large, unprecedented HFMD outbreak in Fuyang city of Anhui province in the central part of southeastern China resulted in a high aggregation of fatal cases. In this study, epidemiologic and clinical investigations, laboratory testing, and genetic analyses were performed to identify the causal pathogen of the outbreak. Of the 6,049 cases reported between 1 March and 9 May of 2008, 3023 (50%) were hospitalized, 353 (5.8%) were severe and 22 (0.36%) were fatal. HEV71 was confirmed as the etiological pathogen of the outbreak. Phylogenetic analyses of entire VP1 capsid protein sequence of 45 Fuyang HEV71 isolates showed that they belong to C4a cluster of the C4 subgenotype. In addition, genetic recombinations were found in the 3D region (RNA-dependent RNA polymerase, a major component of the viral replication complex of the genome) between the Fuyang HEV71 strain and Coxsackievirus A16 (CV-A16), resulting in a recombination virus. In conclusion, an emerging recombinant HEV71 was responsible for the HFMD outbreak in Fuyang City of China, 2008.
A security imbedded authentication protocol (2003)

A authentication protocol with security imbedded into it is reported. It is based on a combination of the private-key and the public-key encryption systems. A Petri-net model of the protocol is presented to verify that the protocol is correct and deadlock-free.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Detection of elevated <i>N</i><sup>ε</sup>‐carboxymethyllysine levels in muscular tissue and in serum of patients with fibromyalgia (2005)

In the interstitial connective tissue of fibromyalgic muscles we found a more intensive staining of the AGE CML, activated NF-kappaB, and also higher CML levels in the serum of these patients compared to the controls. RAGE was only present in FM muscle. AGE modification of proteins causes reduced solubility and high resistance to proteolytic digestion of the altered proteins (e.g. AGE-modified collagens). AGEs can stimulate different types of cells by activation of the transcription factor NF-kappaB, mediated by specific receptors of AGEs (e.g. RAGE) on the cell surface. Both mechanisms may contribute to the development, perpetuation, and spreading of pain characteristic in FM patients.
Data Augmentation Using Random Image Cropping and Patching for Deep CNNs (2019)

Deep convolutional neural networks (CNNs) have achieved remarkable results in image processing tasks. However, their high expression ability risks overfitting. Consequently, data augmentation techniques have been proposed to prevent overfitting while enriching datasets. Recent CNN architectures with more parameters are rendering traditional data augmentation techniques insufficient. In this study, we propose a new data augmentation technique called random image cropping and patching (RICAP) which randomly crops four images and patches them to create a new training image. Moreover, RICAP mixes the class labels of the four images, resulting in an advantage of the soft labels. We evaluated RICAP with current state-of-the-art CNNs (e.g., the shake-shake regularization model) by comparison with competitive data augmentation techniques such as cutout and mixup. RICAP achieves a new state-of-the-art test error of 2.19% on CIFAR-10. We also confirmed that deep CNNs with RICAP achieve better results on classification tasks using CIFAR-100 and ImageNet, an image-caption retrieval task using Microsoft COCO, and other computer vision tasks.
On an information theoretic approach to model anonymous MANET communications (2009)

Measuring communication anonymity (e.g., unlinkability) of anonymous communication systems is a critical, however, unsolved problem. To address this issue, we present an information theoretic model for unlinkability measure for MANETs. Our approach is based on evidence theory, where the basic measuring component is a ldquosetrdquo. We present a traffic slicing method to model mobility followed by theoretical models to evaluate sender and receiver unlinkability, path unlinkability, and system unlinkability.