gebhart/patrepeval huggingface dataset:
Exhaled carbon monoxide in airway diseases: from research findings to clinical relevance (2010)

Breath tests have gained increasing interest in recent years mainly driven by the unmet clinical need to monitor airway diseases and to obtain information of unravelled aspects of respiratory disorders. Carbon monoxide is present in the exhaled breath and has been suggested to reflect ongoing oxidative stress, even if there are some confounding factors limiting its clinical usefulness. Increased concentration of exhaled carbon monoxide has been demonstrated in different acute and chronic airway diseases including allergic rhinitis, asthma, bronchiectasis, and post transplant bronchiolitis obliterans syndrome. Although exhaled carbon monoxide might not prove as a clinically useful biomarker of airway diseases, its measurement has helped to understand the place of heme oxygenase activity in allergic and non-allergic airway diseases. The scope of this review is the exciting field of exhaled carbon monoxide in airway diseases.
A Unified Cognitive Learning Framework for Adapting to Dynamic Environment and Tasks (2021)

Many machine learning frameworks have been proposed and used in wireless communications for realizing diverse goals. However, their incapability of adapting to the dynamic wireless environment and tasks and of self-learning limit their extensive applications and achievable performance. Inspired by the great flexibility and adaptation of primate behaviors due to the brain cognitive mechanism, a unified cognitive learning (CL) framework is proposed for the dynamic wireless environment and tasks. The mathematical framework for our proposed CL is established. Using the public and authoritative dataset, we demonstrate that our proposed CL framework has three advantages, namely, the capability of adapting to the dynamic environment and tasks, the self-learning capability and the capability of 'good money driving out bad money' by taking modulation recognition as an example. The proposed CL framework can enrich the current learning frameworks and widen the applications.
The effect of L-arginine on myocardial recovery after cardioplegic arrest and ischemia under moderate and deep hypothermia. (1997)

Exogenous L-arg considerably improves the postischemic recovery of cardiac mechanical function and CF after cardioplegic arrest and ischemia by stimulation of NO production when given in the reperfusate after both 4 degrees C and 20 degrees C ischemia. However, L-arg as an additive to cardioplegia was only beneficial after 20 degrees C, and not after 4 degrees C ischemia.
A monoclonal antibody against human complement component C2 (1987)

Conference Article| August 01 1987 A monoclonal antibody against human complement component C2 CATHERINE M. ANDERSON; CATHERINE M. ANDERSON 1M.R.C. Immunochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K. Search for other works by this author on: This Site PubMed Google Scholar EDITH SIM EDITH SIM * Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1987) 15 (4): 660–661. https://doi.org/10.1042/bst0150660 Article history Received: November 28 1986 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation CATHERINE M. ANDERSON, EDITH SIM; A monoclonal antibody against human complement component C2. Biochem Soc Trans 1 August 1987; 15 (4): 660–661. doi: https://doi.org/10.1042/bst0150660 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1987 Biochemical Society1987 Article PDF first page preview Close Modal You do not currently have access to this content.
Sugar‐Derived Phase‐Selective Molecular Gelators as Model Solidifiers for Oil Spills (2010)

Aufwischen: Phasenselektive Geliermittel, die biokatalytisch aus Zuckeralkoholen hergestellt wurden, gelieren selektiv und bei Raumtemperatur organische Flüssigkeiten, einschließlich Rohölfraktionen, in Gegenwart von Wasser. Das Öl kann aus der Gelphase durch Erhitzen und Destillieren zurückgewonnen werden. Das könnte diese Materialklasse für den Einsatz bei Ölkatastrophen interessant machen. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Prevalence of viral infection detected by PCR and RT‐PCR in patients with acute exacerbation of COPD: A systematic review (2010)

This systematic review demonstrated that viruses are strongly associated with AECOPD, with the highest detection rates of viruses being in Europe. The geographical epidemiology of viruses may have important therapeutic implications for management of AECOPD.
The impact of onychomycosis on quality of life (1997)

Onychomycosis is a common disease, which is estimated to affect approximately 3% of the UK population. It is often viewed as being relatively trivial in nature; however, there has been little research to evaluate how this condition affects patients' physical and psychological well-being. The aim of this study was to assess the possible effect of onychomycosis on different aspects of patients' quality of life.
Total Productivity Management and the Theory of Constraints: An Integrated Application of Supply Chain Management Methods (2007)

AbstractThe following sections are included:IntroductionSCM and the Indicators of TOCConcrete Measures that Improve TOC Main Indicators, and BSCUseful TP Management for Goals/Measures Deployment in SCMExamination of an Example Applying TP Management to SCMConcluding RemarksReferences
The effect of spironolactone on sweat and urinary sodium excretion during exercise in humans (2009)

This study examined the effect of spironolactone on urinary ([Na(+)](urine)) and sweat sodium concentration ([Na(+)](sweat)) when controlling for sweat rate. Fifteen healthy subjects were required to complete two 90-min exercise bouts (three 30-min ordered exercise bouts at 60%, 70%, and 80% of the subjects' age-predicted maximum heart rate) in a 35 degrees C and 40% relative humidity environmental chamber, once after administration of 300 mg spironolactone, and once after administration of 300 mg placebo. Both the drug and placebo were taken over an 18 h period, with the second 100 mg dose taken 6 h prior to exercise, and the first 200 mg dose taken 12 h prior to the second dose. Sweat rate was measured during each of the three exercise bouts using a Macroduct sweat collector affixed to the flexor surface of the forearm. Urine sodium excretion rate was calculated for the three hour period immediately prior to each exercise bout. Urinary and sweat sodium concentrations were analyzed via flame photometry. Spironolactone had no effect on [Na(+)](sweat) at the different sweat rates. However, the urinary sodium excretion rate was significantly higher with spironolactone use (P<0.05). These results demonstrate that spironolactone caused the expected natriuresis, but greater sodium excretion was not observed in the sweat gland. Since the mineralocorticoid receptors (MR) in the sweat gland were not antagonized by spironolactone in the same manner as those in the kidney, this suggests that different isoforms of the MR exist in the kidney and the sweat gland of humans.
Charge recombination in polymer/fullerene photovoltaic devices (2013)

Solar cells based on polymer–fullerene blends are amongst the most efficient organic photovoltaic devices with power conversion efficiencies now exceeding 3%. The large interfacial area in such dispersed heterojunctions, which is essential for charge separation, also enables charge recombination. Understanding recombination is, therefore, of key importance in the optimisation of device performance. Recent measurements of charge recombination in blends of poly(2-methoxy-5-(3′,7′-dimethyloctyloxy)-1-4-phenylene vinylene), (MDMO-PPV) and 1-(3-methoxycarbonyl)-propyl-1-phenyl-(6,6)C61 (PCBM) by transient optical spectroscopy reveal that recombination dynamics possess two phases, one fast, intensity dependent phase and a slow, intensity independent phase which dominates at low light intensities. The recombination is thermally activated, and the kinetics are sensitive to background illumination but insensitive to the blend composition. Simple models of bimolecular recombination cannot explain these features. In this article, we present a model for the mechanism of charge recombination, based on multiple trapping of polarons by a distribution of traps in the polymer phase. The model explains the observed recombination kinetics and their dependence on light intensity, temperature and fullerene concentration. We show that under solar illumination conditions, charge recombination is limited by the activation of positive polarons out of deep traps, yet carrier collection competes successfully with recombination in thin films. The model is evaluated by comparison with data on cells and independent measurements of charge carrier mobility, and the implications for cell performance are discussed
Validation of a RP-HPLC Method for the Quantitation of Vorinostat in Rat Plasma and its Application to a Pharmacokinetic Study (2015)

A simple, specific and reproducible high-performance liquid chromatography (HPLC) assay method has been developed and validated for the estimation of vorinostat in rat plasma. The bioanalytical procedure involves extraction of vorinostat and phenacetin (internal standard, IS) from rat plasma with simple liquid-liquid extraction process. The chromatographic analysis was performed on a Waters Alliance system using a gradient mobile phase conditions at a flow rate of 1.0 mL/min and Symmetry Shield C 18 column maintained at 35 1C. The eluate was monitored using an UV detector set at 245 nm. Vorinostat and IS eluted at 5.3 and 6.3 min, respectively and the total run time was 10 min. Method validation was performed as per FDA guidelines and the results met the acceptance criteria. The calibration curve was linear over a concentration range of 255-5566 ng/mL (r 2 = 0.995). The intra-and inter-day precisions were in the range of 2.60-7.93 and 3.99-8.64%, respectively. The validated HPLC method was successfully applied to a pharmacokinetic study in rats.
New quinoline derivatives as amoebicidal and cysticidal agents. (1981)

Why does a first pregnancy after age 35 increase the risk of breast cancer, and what can be done to combat this?
Technological Platform for Vertical Multi-Wafer Integration of Microscanners and Micro-Optical Components (2019)

We describe an original integration technological platform for the miniaturization of micromachined on-chip optical microscopes, such as the laser scanning confocal microscope. The platform employs the multi-wafer vertical integration approach, combined with integrated glass-based micro-optics as well as micro-electro-mechanical systems (MEMS) components, where the assembly uses the heterogeneous bonding and interconnecting technologies. Various heterogeneous components are disposed in vertically stacked building blocks (glass microlens, MEMS actuator, beamsplitter, etc.) in a minimum space. The platform offers the integrity and potential of MEMS microactuators integrated with micro-optics, providing miniaturized and low cost solutions to create micromachined on-chip optical microscopes.
All-Copper Chip-to-Substrate Interconnects Part I. Fabrication and Characterization (2008)

A fabrication process has been developed and characterized to create all-copper chip-to-substrate input/output connections. Electroless copper plating followed by low-temperature annealing in a nitrogen environment was used to create an all-copper bond between copper pillars. The ability to fuse the two copper surfaces at modest temperature and pressure is demonstrated. The bond strength for the all-copper structure exceeded after annealing at . During the anneal process, a significant microstructural transformation in the bonded copper–copper interface was observed. The changes were correlated to an increase in the bond strength. The process was characterized with respect to in-plane misalignment of bond sites. Significant planar misalignment, greater than the diameter of the pillars, could be tolerated. Through-plane mismatches between the pillars (pillar gap) as large as could be overcome, resulting in good pillar-to-pillar bonding. Successful silicon-on-silicon and silicon-on-FR-4 bonding was achieved with no degradation of the organic board.
Enzymatic preparation of enantiomerically pure <i>sn</i>‐2,3‐diacylglycerols: A stereoselective ethanolysis approach (2006)

Abstract Stereoselective ethanolysis of monoacid TAG by immobilized Rhizomucor miehei lipase (RML) was studied for preparation of optically pure sn ‐2,3‐DAG. Trioctanoylglycerol (TO) was used as a model substrate. The enantiomeric purity of the product, sn ‐2,3‐dioctanoylglycerol ( sn ‐2,3‐DO), was very high (percent enantiomeric excess >99%) when an excess of ethanol was used. The result indicated that RML was highly stereoselective toward the sn ‐1 position of TO under conditions of excess ethanol. The stereoselectivity of RML depended on the amount of ethanol. The larger the amount of ethanol was, the higher the stereoselectivity became. After optimizing the parameters such as reactant molar ratio, water content, and temperature, (ethanol/TO molar ratio =31∶1 and water content =7.5 wt% of the reactants at 25°C), optically pure sn ‐2,3‐DO was obtained at 61.1 mol% in the glyceride fraction in 20 min. The above conditions were further applied for ethanolysis of monoacid TAG with different acyl groups such as tridecanoylglycerol (C10∶0), tridodecanoylglycerol (C12∶0), tritetradecanoylglycerol (C14∶0) and trioctadecenoylglycerol [triolein, (C18∶1)]. The yields and enantiomeric purities of 1,2(2,3)‐DAG were dramatically reduced when TAG with FA longer than decanoic acid were used.
Methylation of naphthalene by methane over substituted aluminophosphate molecular sieves (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMethylation of naphthalene by methane over substituted aluminophosphate molecular sievesSimon J. X. He, Mervyn A. Long, Moetaz I. Attalla, and Michael A. WilsonCite this: Energy Fuels 1992, 6, 4, 498–502Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July 1992https://pubs.acs.org/doi/10.1021/ef00034a022https://doi.org/10.1021/ef00034a022research-articleACS PublicationsRequest reuse permissionsArticle Views227Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Acetaminophen confers neuroprotection during early cerebral ischemia-reperfusion (2009)

Stroke is the leading cause of disability in the United States. It usually occurs from a clot blocking a cerebral artery, resulting in cerebral ischemia and infarction. Few stroke therapeutics are available that definitively improve patient outcome. Acetaminophen is a readily available, inexpensive drug with a good safety profile - properties desirable of a neuroprotectant. We have previously shown acetaminophen to be effective following myocardial infarction. Since similar cell-destructive events occur during cerebral ischemia as in myocardial infarction, we sought to determine whether acetaminophen would protect neuronal cells in a similar fashion. Biochemical and molecular assays were employed to assess cell death and mitochondrial function. Acetaminophen significantly reduced cerebral infarct size, mitochondrial swelling and rupture as well as apoptosis. Acetaminophen also preserved mitochondrial membrane potential. Furthermore, acetaminophen prevented cerebral edema, as seen histopathologically. Taken together, these data suggest that acetaminophen is effective in preventing neuronal stroke damage.
Integrated Acoustic Evaluation of Reservoir Fractures: From Borehole Out Into the Formation (2011)

An integrated approach for evaluating reservoir fractures using borehole acoustic-log data is presented. This approach combines borehole ultrasonic imaging, Stoneley-wave reflection, cross-dipole anisotropy, and the recently developed shear-wave reflection imaging techniques to provide an overall assessment of fracture permeability, orientation, and its connectivity around the wellbore. Evaluating Stoneley reflection over different frequency ranges allows us to detect permeable structures in formation. These structures, when aligned in a preferential direction, give rise to significant acoustic anisotropy from the cross-dipole measurement that characterizes them as permeable fractures. However, the fractures measured by these conventional acoustic techniques could also be the drilling-induced fractures that do not extend into the formation. Integrating the conventional measurements with shear-wave reflection imaging allows us to assess the connectivity of the fractures in the near-well region. In addition to the borehole guided flexural mode a dipole acoustic tool generates shear body waves that radiate away from the borehole and strike a fracture surface, and records the shear reflection from the fracture. The reflection of the shear waves, particularly the shear waves that polarize parallel to the fracture surface, are sensitive to open fractures in the vicinity of the well, allowing the fractures to be imaged using the dipole-shear reflection data. We use case examples to demonstrate the effectiveness of this integrated acoustic fracture evaluation approach.
A rapid DNA isolation procedure from Petri dish grown clinical bacterial isolates (1990)

Journal Article A rapid DNA isolation procedure from Petri dish grown clinical bacterial isolates Get access Kamalendu Nath Kamalendu Nath C.W. Post Campus of Long Island University, Molecular Biology, Department of BiologyBrookville, NY 11548, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 18, Issue 21, 21 November 1990, Page 6462, https://doi.org/10.1093/nar/18.21.6462 Published: 21 November 1990 Article history Received: 19 September 1990 Published: 21 November 1990
Personalizing information retrieval for multi-session tasks (2010)

Dwell time as a user behavior has been found in previous studies to be an unreliable predictor of document usefulness, with contextual factors such as the user's task needing to be considered in its interpretation. Task stage has been shown to influence search behaviors including usefulness judgments, as has task type. This paper reports on an investigation of how task stage and task type may help predict usefulness from the time that users spend on retrieved documents, over the course of several information seeking episodes. A 3-stage controlled experiment was conducted with 24 participants, each coming 3 times to work on 3 sub-tasks of a general task, couched either as "parallel" or "dependent" task type. The full task was to write a report on the general topic, with interim documents produced for each sub-task. Results show that task stage can help in inferring document usefulness from decision time, especially in the parallel task. The findings can be used to increase accuracy in predicting document usefulness and accordingly in personalizing search for multi-session tasks.
Pythium oligandrum: an example of opportunistic success (2012)

Pythium oligandrum, a non-pathogenic soil-inhabiting oomycete, colonizes the root ecosystem of many crop species. Whereas most members in the genus Pythium are plant pathogens, P. oligandrum distinguishes itself from the pathogenic species by its ability to protect plants from biotic stresses in addition to promoting plant growth. The success of P. oligandrum at controlling soilborne pathogens is partly associated with direct antagonism mediated by mycoparasitism and antimicrobial compounds. Interestingly, P. oligandrum has evolved with specific mechanisms to attack its prey even when these belong to closely related species. Of particular relevance is the question of how P. oligandrum distinguishes between self- and non-self cell wall degradation during the mycoparasitic process of pathogenic oomycete species. The ability of P. oligandrum to enter and colonize the root system before rapidly degenerating is one of the most striking features that differentiate it from all other known biocontrol fungal agents. In spite of this atypical behaviour, P. oligandrum sensitizes the plant to defend itself through the production of at least two types of microbe-associated molecular patterns, including oligandrin and cell wall protein fractions, which appear to be closely involved in the early events preceding activation of the jasmonic acid- and ethylene-dependent signalling pathways and subsequent localized and systemic induced resistance. The aim of this review is to highlight the expanding knowledge of the mechanisms by which P. oligandrum provides beneficial effects to plants and to explore the potential use of this oomycete or its metabolites as new disease management strategies.
Spaceborne profiling of atmospheric temperature and particle extinction with pure rotational Raman lidar and of relative humidity in combination with differential absorption lidar: performance simulations (2006)

The performance of a spaceborne temperature lidar based on the pure rotational Raman (RR) technique in the UV has been simulated. Results show that such a system deployed onboard a low-Earth-orbit satellite would provide global-scale clear-sky temperature measurements in the troposphere and lower stratosphere with precisions that satisfy World Meteorological Organization (WMO) threshold observational requirements for numerical weather prediction and climate research applications. Furthermore, nighttime temperature measurements would still be within the WMO threshold observational requirements in the presence of several cloud structures. The performance of aerosol extinction measurements from space, which can be carried out simultaneously with temperature measurements by RR lidar, is also assessed. Furthermore, we discuss simulations of relative humidity measurements from space obtained from RR temperature measurements and water-vapor data measured with the differential absorption lidar (DIAL) technique.