gebhart/patrepeval huggingface dataset:
High-frequency ultrasound imaging of size-isolated microbubbles in mice (2009)

Microbubbles were isolated by size using differential centrifugation, and the effect of microbubble size on the acoustics and kinetics of contrast ultrasound imaging was measured in the mouse kidney. Microbubbles in the 1-2 ¿m diameter size range comprise over 90% of the microbubbles in freshly generated and commercially available lipid-coated microbubbles. These smaller microbubbles attenuated strongly without producing much backscatter, thus behaving like a negative contrast agent. The high degree of ultrasound absorption may be due to strong damping by the shell. On the other hand, microbubbles in the 4-5 and 6-8 ¿m diameter size ranges were highly echogenic. Also, larger microbubbles exhibited longer contrast persistence, indicating that dissolution is the main mechanism of elimination. For example, 6-8 ¿m diameter microbubbles circulated for greater than 15 minutes at a dose of 5×10^8 microbubbles/mL in a 0.1-mL bolus. These results demonstrate that the magnitude and duration of contrast enhancement is strongly dependent on the microbubble size distribution.
<i>In vivo</i> and <i>in vitro</i> effects of curcumin on head and neck carcinoma: a systematic review (2016)

This systematic review demonstrated that curcumin is effective on HNSCC cell proliferation and survival, reinforcing the currently available evidence that curcumin could be an adjuvant drug in HNSCC treatment.
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice (2011)

In chronic kidney disease, fibroblast dysfunction causes renal fibrosis and renal anemia. Renal fibrosis is mediated by the accumulation of myofibroblasts, whereas renal anemia is mediated by the reduced production of fibroblast-derived erythropoietin, a hormone that stimulates erythropoiesis. Despite their importance in chronic kidney disease, the origin and regulatory mechanism of fibroblasts remain unclear. Here, we have demonstrated that the majority of erythropoietin-producing fibroblasts in the healthy kidney originate from myelin protein zero-Cre (P0-Cre) lineage-labeled extrarenal cells, which enter the embryonic kidney at E13.5. In the diseased kidney, P0-Cre lineage-labeled fibroblasts, but not fibroblasts derived from injured tubular epithelial cells through epithelial-mesenchymal transition, transdifferentiated into myofibroblasts and predominantly contributed to fibrosis, with concomitant loss of erythropoietin production. We further demonstrated that attenuated erythropoietin production in transdifferentiated myofibroblasts was restored by the administration of neuroprotective agents, such as dexamethasone and neurotrophins. Moreover, the in vivo administration of tamoxifen, a selective estrogen receptor modulator, restored attenuated erythropoietin production as well as fibrosis in a mouse model of kidney fibrosis. These findings reveal the pathophysiological roles of P0-Cre lineage-labeled fibroblasts in the kidney and clarify the link between renal fibrosis and renal anemia.
GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle (2006)

Obesity is associated with insulin resistance in skeletal muscle; accordingly, weight loss dramatically improves insulin action. We sought to identify molecular remodeling of muscle commensurate with weight loss that could explain improvements in insulin action. Muscle from morbidly obese women was studied before and after gastric bypass surgery. Gastric bypass surgery significantly reduced body mass by approximately 45% and improved insulin action. We then assessed mRNA profiles using a stringent statistical analysis (statistical concordance with three probe set algorithms), with validation in a cross-sectional study of lean (n = 8) vs. morbidly obese (n = 8) muscle. Growth factor receptor-bound protein 14 (GRB14), glycerol-3-phosphate dehydrogenase 1 (GPD1), and growth differentiation factor 8 (GDF8; myostatin) significantly decreased approximately 2.4-, 2.2-, and 2.4-fold, respectively, after weight loss (gastric bypass). Increased expression of these transcripts was associated with increased obesity in the cross-sectional group (lean vs. morbidly obese muscle). Each transcript was validated by real-time quantitative RT-PCR assays in both study groups. Using Ingenuity Pathway Analysis, we show that all three transcripts are involved in the same regulatory network including AKT1, IGF1, TNF, PPARG, and INS. These results suggest that GRB14, GPD1, and GDF8 are weight loss-responsive genes in skeletal muscle and that the observed transcriptional modulation of these would be expected to improve insulin signaling, decrease triglyceride synthesis, and increase muscle mass, respectively, with weight loss. Thus our data provide a possible regulatory pathway involved in the development of insulin resistance in the morbidly obese state, and improvement of insulin resistance with weight loss.
Emergent Linguistic Rules from Inducing Decision Trees: Disambiguating Discourse Clue Words (1994)

We apply decision tree induction to the problem of discourse clue word sense disambiguation with a genetic algorithm. The automatic partitioning of the training set which is intrinsic to decision tree induction gives rise to linguistically viable rules.
pH-Induced Switchable Superwettability of Efficient Antibacterial Fabrics for Durable Selective Oil/Water Separation (2017)

The superhydrophobic antibacterial fabrics with intelligent switchable wettability were fabricated by the cross-link reaction among pH-responsive antibacterial copolymer tethered hydroxyl groups, methylol-contained poly(ureaformaldehyde) nanoparticles (PUF NPs), and hexamethylene diisocyanate. It was found that the surface concentration of N<sup>+</sup> were heavily influenced by acid solutions, resulting in the rapid wettability conversion from superhydrophobicity/superoleophilicity to superhydrophilicity/underwater superoleophobicity in a remarkably short time. The above responsiveness feature of coated cotton fabric contributes a prominent selective oil/water separation property, and the separation efficiency invariably remained at greater than 95% even after 20 reuse cycles, which exhibited brilliant durability. More importantly, the coated cotton fabric possessed excellent self-cleaning performance after contamination by oil and held high bactericidal rate (more than 80%) regardless of pH treatment, and thus could abate the surface biological pollution caused by bacteria proliferation. The attractive properties of the prepared smart superwetting materials shows great promise for potential application in oil/water separation from an environmental-protection perspective.
RASCAL - an autonomous ground vehicle for desert driving in the DARPA grand challenge 2005 (2005)

The DARPA Grand Challenge is a competition of autonomous ground vehicles in the Mojave desert, with a prize of } for the winner. This event was organized in 2004 and held annually at least until 2007, until a team wins the prize. The teams are coming from various background, but the rule that no US government funding or technology that was created with US government funding could be used for this competition, prevented some of the well established players to participate. The team SciAutonics/Auburn-Engineering continues their effort to build a system for participation in this challenge, based on the 2004 entry RASCAL. The main focus in the system design is on improvements of the design from 2004. Novel sensing modalities the team plans to use in 2005, are a stereo vision system and a radar system for obstacle detection. Offline simulation allows to analyze situations in the laboratory and to replay recordings from sensors. The Grand Challenge 2005 takes place on October 8, and the SciAutonics/Auburn team intends to compete with the improved RASCAL system.
An autonomous distributed vehicle-to-grid control of grid-connected electric vehicle (2009)

Penetrating large amount of renewable energy resources into power system, battery energy storage system perform important role for smoothing their natural variability, ensuring grid-wide frequency stability, and suppressing voltage rise caused by reverse power flow. The ubiquitous power grid concept has been proposed as a Japanese smart grid, in where total battery capacity could be optimized by coordinating controllable distributed generators, loads on demand side, for example, heat pump system with heat storage, and plug-in hybrid vehicle or battery electric vehicle with onboard battery. In this paper, we propose a vehicle-to-grid control of grid-connected plug-in hybrid electric vehicle and electric vehicle as a kind of the demand response in the ubiquitous power grid. Proposed control is based on simple droop characteristics against the power system frequency at plug-in terminal, and considers the risks about use for vehicle and battery condition. Autonomous distributed Smart Storage for governor free control, spinning reserve, local area voltage control, and other smart grid applications is realized by packaging the proposed control to automotive power electronics circuit and electric control unit.
TeaStore: A Micro-Service Reference Application for Benchmarking, Modeling and Resource Management Research (2018)

Modern distributed applications offer complex performance behavior and many degrees of freedom regarding deployment and configuration. Researchers employ various methods of analysis, modeling, and management that leverage these degrees of freedom to predict or improve non-functional properties of the software under consideration. In order to demonstrate and evaluate their applicability in the real world, methods resulting from such research areas require test and reference applications that offer a range of different behaviors, as well as the necessary degrees of freedom. Existing production software is often inaccessible for researchers or closed off to instrumentation. Existing testing and benchmarking frameworks, on the other hand, are either designed for specific testing scenarios, or they do not offer the necessary degrees of freedom. Further, most test applications are difficult to deploy and run, or are outdated. In this paper, we introduce the TeaStore, a state-of-the-art micro-service-based test and reference application. TeaStore offers services with different performance characteristics and many degrees of freedom regarding deployment and configuration to be used as a benchmarking framework for researchers. The TeaStore allows evaluating performance modeling and resource management techniques; it also offers instrumented variants to enable extensive run-time analysis. We demonstrate TeaStore's use in three contexts: performance modeling, cloud resource management, and energy efficiency analysis. Our experiments show that TeaStore can be used for evaluating novel approaches in these contexts and also motivates further research in the areas of performance modeling and resource management.
The emerging era of supramolecular polymeric binders in silicon anodes (2018)

Silicon (Si) anode is among the most promising candidates for the next-generation high-capacity electrodes in Li-ion batteries owing to its unparalleled theoretical capacity (4200 mA h g<sup>-1</sup> for Li<sub>4.4</sub>Si) that is approximately 10 times higher than that of commercialized graphitic anodes (372 mA h g<sup>-1</sup> for LiC<sub>6</sub>). The battery community has witnessed substantial advances in research on new polymeric binders for silicon anodes mainly due to the shortcomings of conventional binders such as polyvinylidene difluoride (PVDF) to address problems caused by the massive volume change of Si (300%) upon (de)lithiation. Unlike conventional battery electrodes, polymeric binders have been shown to play an active role in silicon anodes to alleviate various capacity decay pathways. While the initial focus in binder research was primarily to maintain the electrode morphology, it has been recently shown that polymeric binders can in fact help to stabilize cracked Si microparticles along with the solid-electrolyte-interphase (SEI) layer, thus substantially improving the electrochemical performance. In this review article, we aim to provide an in-depth analysis and molecular-level design principles of polymeric binders for silicon anodes in terms of their chemical structure, superstructure, and supramolecular interactions to achieve good electrochemical performance. We further highlight that supramolecular chemistry offers practical tools to address challenging problems associated with emerging electrode materials in rechargeable batteries.
Upregulation of Bcl-2 Through Caspase-3 Inhibition Ameliorates Ischemia/Reperfusion Injury in Rat Cardiac Allografts (2001)

Bcl-2 is actively downregulated and TNF-alpha is upregulated in this model of cardiac allograft ischemia/reperfusion. Furthermore, the caspase-3 pathway is linked to this process, and blockade of caspase-3 can ameliorate reperfusion injury by upregulating bcl-2 and inhibiting TNF-alpha without affecting cytochrome c release.
Defect property correlations in garnet crystals. II. Electrical conductivity and optical absorption in Ca3Al2Ge3O12 (1985)

Electrical conductivity and ionic transference measurements performed at varying temperatures and partial pressures of oxygen show that CALGAR (Ca3Al2Ge3O12), a luminescent garnet, is a mixed ionic-electronic conductor. An activation energy of 1 eV for ionic diffusion is measured. An absorption band at 400 nm, whose magnitude can be controlled by varying the annealing atmosphere, is attributed to an O− center.
Decentralized Interference Aware Link Adaptation Using Busy Bursts (2007)

This paper presents a new cross-layer approach to achieve active link adaptation and QoS support in ad hoc networks. Upon data reception in a transmission slot, receivers broadcast a feedback signal in a time-multiplexed mini-slot. The level of this feedback or busy signal is made dependent on the received signal from the intended transmitter and the required SINR (signal-to-interference-plus-noise ratio). Potential new interfering transmitters adjust their data transmit power based on the received busy signal power. It is demonstrated that due to the channel reciprocity in TDD (time division duplex) the received busy signal power is sufficient information to be able to maintain the SINR at the already existing links. Since multiple links are coupled via the busy signal, convergence and stability issues are analyzed.
Location, location, location: alterations in the functional topography of face- but not object- or place-related cortex in adolescents with autism (2010)

In autism, impairments in face processing are a relatively recent discovery, but have quickly become a widely accepted aspect of the behavioral profile. Only a handful of studies have investigated potential atypicalities in autism in the development of the neural substrates mediating face processing. High-functioning individuals with autism (HFA) and matched typically developing (TD) controls watched dynamic movie vignettes of faces, common objects, buildings, and scenes of navigation while undergoing an fMRI scan. With these data, we mapped the functional topography of category-selective activation for faces bilaterally in the fusiform gyrus, occipital face area, and posterior superior temporal sulcus. Additionally, we mapped category-selective activation for objects in the lateral occipital area and for places in the parahippocampal place area in the two groups. Our findings do not indicate a generalized disruption in the development of the entire ventral visual pathway in autism. Instead, our results suggest that the functional topography of face-related cortex is selectively disrupted in autism and that this alteration is present in early adolescence. Furthermore, for those HFA adolescents who do exhibit face-selective activation, this activation tends to be located in traditionally object-related regions, which supports the hypothesis that perceptual processing of faces in autism may be more akin to the perceptual processing of common objects in TD individuals.
A multi-state memory using resonant tunneling diode pair (1991)

A multistate memory using the resonant tunneling diode (RTD) pair is described. Two RTDs in series can have 2N+1 stable states. With this concept, a five stable states memory cell has been implemented with two 2-peak RTDs. This device should provide high packing density and low power consumption. Encoder and decoder circuits are given as an example to communicate with the computational modules which use binary logic.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Comparative immunohistochemical characterization of canine seminomas and Sertoli cell tumors (2009)

Primary testicular tumors are the most common causes of cancer in male dogs. Overall, the majority of canine patients should be cured by testicular surgery. However, tumor markers are not well-known in veterinary medicine. We sought to determine using immunohistochemistry whether the combined human testicular tumor markers (placental alkaline phosphatase, OCT3/4, CD30, alpha-fetoprotein, inhibin-alpha, vimentin, c-KIT, and desmin) are expressed in canine seminomas and Sertoli cell tumors (SCTs). We examined 35 canine testicular tumors, 20 seminomas and 15 SCTs. c-KIT was expressed markedly in canine seminomas. Both inhibin-alpha and vimentin were expressed significantly in canine SCTs. The results of this study demonstrate differences and similarities between tumor marker expression of testicular tumors in dogs and humans. All the main markers in current routine use are discussed as well as potential useful markers for benign and malignant tumors, and tumor progression.
Cardiac Involvement in Hemochromatosis (2013)

Cardiac hemochromatosis or primary iron-overload cardiomyopathy is an important and potentially preventable cause of heart failure. This is initially characterized by diastolic dysfunction and arrhythmias and in later stages by dilated cardiomyopathy. Diagnosis of iron overload is established by elevated transferrin saturation (>55%) and elevated serum ferritin (>300 ng/mL). Genetic testing for mutations in the HFE (high iron) gene and other proteins, such as hemojuvelin, transferrin receptor, and ferroportin, should be performed if secondary causes of iron overload are ruled out. Patients should undergo comprehensive 2D and Doppler echocardiography to evaluate their systolic and diastolic function. Newer modalities like strain imaging and speckle-tracking echocardiography hold promise for earlier detection of cardiac involvement. Cardiac magnetic resonance imaging with measurement of T2* relaxation times can help quantify myocardial iron overload. In addition to its value in diagnosis of cardiac iron overload, response to iron reduction therapy can be assessed by serial imaging. Therapeutic phlebotomy and iron chelation are the cornerstones of therapy. The average survival is less than a year in untreated patients with severe cardiac impairment. However, if treated early and aggressively, the survival rate approaches that of the regular heart failure population.
Ground roll; rejection using polarization filters (1990)

Abstract Ground roll noise on land data sets overwhelms the desired reflection seismic signal unless special steps are taken in data acquisition and processing to control it. This is usually done in the field by the design of group arrays for data acquisition. On the other hand, if multicomponent data are acquired, it is possible to remove ground roll during processing using polarization analysis. Even though this processing is computation-intensive, the potential exists for obtaining results similar to conventional data acquisition, but with deployment of fewer sensors in the field with minimal group array effects. It also has potential for deriving new information.We describe a two-dimensional polarization-filter analysis for use with vertical and in-line sensors. A time-domain spectral matrix technique is developed since the recorded seismic signal is the superposition of multiple signals in the time domain, each with different frequency content and time-varying polarization. This technique is implemented by decomposing the signal into individual frequency components using narrow band-pass filters and defining the polarization characteristic using sliding time windows. We show that both incoherent noise and specific linearly polarized constituents can be successfully filtered.
RHODIUM CARBONYL-CATALYZED CROSS-HYDROCARBONYLATION OF ACETYLENES AND ETHYLENE. SYNTHESIS OF α,β-UNSATURATED KETONES (1982)

Abstract The cross-hydrocarbonylation of acetylenes and ethylene with CO and H2 in the presence of Rh4(CO)12 gave α,β-unsaturated ethyl ketones regio- and stereoselectively.
CIS 89A: Web Page Development - Syllabus (2015)

DESCRIPTION Fundamentals of Web page design and creation: designing, encoding, and maintaining pages on the World Wide Web using HTML/XHTML. Course format is skill-based practice using HTML and Cascading Style Sheets (CSS) along with question-based student discussions. This is the online distance learning section. The course includes directed activities to design and develop web pages using web-based technologies. There is also reading, discussing, critical thinking to encourage application of development skills in a broader context. REQUISITES Advisory: English Writing 211 and Reading 211 (or Language Arts 211), or English as a Second Language 272 and 273; Computer Information Systems 18A. This is an ONLINE course. There are NO on-campus meetings. You are REQUIRED to participate in the online class activities such as discussions in addition to doing the weekly individual assignments. You must be able to access and participate several times per week. DAILY access to the course is strongly recommended. Students who do not participate actively in discussions and regularly submit assignments throughout the quarter will be dropped from the course by the instructor, as required by State funding rules. The instructor will discuss individual situations if the student emails an explanation and a plan. If you need a credit for this course keep this in mind. Course Notes: Online course. Students must have access to a computer, the Web and an individual e-mail address. NO on-campus exams Information on REQUIRED orientation available at http://www.deanza.edu/distance/