gebhart/patrepeval huggingface dataset:
Time series forecasting of cloud data center workloads for dynamic resource provisioning (2015)

Cloud computing offers on-demand, elastic resource provisioning that allows an enterprise to provide services to their customers at an acceptable quality while consuming only the requisite computing resources as a utility. Since cloud computing resources scale elastically, utilizing cloud computing re-duces the risk of over-provisioning, wasting resources during non-peak hours, and reduces the risk of under-provisioning, missing potential customers. By using an automated resource scaling algorithm, a system implemented using cloud services can fully exploit the benefits of on-demand elasticity. A simple reactive scaling algorithm, resource scaling is triggered after some monitored metric has crossed a threshold, suffers from the fact that cloud computing workloads can varying widely over time and a scalable application needs time to perform the triggered scaling action. Instead, resources can be proactively requested by forecasting future resource demand values based on demand history. Obtaining accurate prediction results is crucial to the efficient operation of an automated resource scaling algorithm. In this work, several forecasting models are evaluated for their applicability in forecasting cloud computing workloads. These forecasting methods were compared for their ability to forecast real cloud computing workloads including Google cluster data and Intel Netbatch logs. Two tests are performed to evaluate the accuracy of each forecasting model: out-of-sample forecast-ing and rolling forecast origin cross-validation.
A high density NAND EEPROM with block-page programming for microcomputer applications (1989)

A 5 V-only 4 Mb NAND EEPROM (electrically erasable programmable read-only memory) has been successfully developed. The EEPROM has on-chip high-voltage generators, so the system needs only a 5 V power supply. The block-page erase/program mode realizes high-speed programming. On-chip test circuits provide high reliability. The NAND EEPROM has many applications for compact microcomputer systems, which need large storage systems with low power consumption
EMG-based teleoperation of a robot arm in planar catching movements using ARMAX model and trajectory monitoring techniques (2006)

This paper presents a methodology of teleoperating a robot arm, using electromyographic (EMG) signals and a trajectory monitoring technique based on human motion analysis. EMG signals from the flexor and extensor muscles of the elbow joint are used to predict the human elbow joint angle, using an auto-regressive moving average with exogenous output (ARMAX) model. A position tracker is attached in the user upper arm, before the elbow joint. It has been identified from previous works on human physiology that the trajectory of the human hand during planar catching tasks lays on a straight line. This motion law is used in order to monitor and refine the trajectory of the human hand that is predicted through EMG and the ARMAX model. The experimental results show that the ARMAX model estimation for the elbow angle, in conjunction with the trajectory monitoring technique, is able to predict the user motion with high accuracy, within different target points unknown to the system, and various hand velocities
Design and implementation of heterogeneous distributed multimedia system using mosaic GSQL (1995)

Abstract With more and more computer users having access to the Internet, it is important for them to access the vast amount of information in an efficient and easy manner. This project explores one of the possibilities for providing an integrated system to the user to access the different types of media like text, image, audio and video stored in different databases on remote machines without the user having to know about the underlying mechanism involved in accessing the database. Such a system must hide the location of the remote data, retrieve the information, process the results and present it to the user. We have used the National Center for Supercomputer Applications (NCSA) Mosaic's Gateway Structured Query Language (GSQL), which enables a system developer to build input forms, query to the remote database in a relatively easy manner and present the results to the user. With the help of this prototype, the development time to build such an application is considerably reduced as compared with developing the same application using the existing Graphical User Interface (GUI) tools like the X‐Window system.
Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight (2019)

We found that exposure of adult animals to calorie-dense foods rapidly abolished expression of mitofusin 2 (Mfn2), a gene promoting mitochondrial fusion and mitochondrion-endoplasmic reticulum interactions, in white and brown fat. Mfn2 mRN was also robustly lower in obese human subjects compared with lean controls. Adipocyte-specific knockdown of Mfn2 in adult mice led to increased food intake, adiposity, and impaired glucose metabolism on standard chow as well as on a diet with high calorie content. The body weight and adiposity of mature adipocyte-specific Mfn2 knockout mice on a standard diet were similar to those of control mice on a high-fat diet. The transcriptional profile of the adipose tissue in adipocyte-specific Mfn2 knockout mice was consistent with adipocyte proliferation, increased lipogenesis at the tissue level, and decreased glucose utilization at the systemic level. These observations suggest a possible crucial role for mitochondrial dynamics in adipocytes in initiating systemic metabolic dysregulation.
Development of an Automatic Gain Controller Card for Next Generation EDFAs (2003)

This paper describes a low cost automatic gain controller card that provides fast transient gain control to maintain the power of the surviving channels when the number of input channels to an erbium-doped fiber amplifier (EDFA) changes rapidly.
Transvascular and Intracardiac Two‐Dimensional Echocardiography (1990)

Recent developments in transesophageal and catheter-based ultrasound instrumentation have allowed invasive ultrasound imaging. This experimental study presents a new application of invasive ultrasound, transvascular and intracardiac ultrasound imaging. In six pigs, we introduced a 7-mm, 5-MHz esophageal ultrasound probe into both the abdominal aorta and inferior vena cava and explored the imaging potential of this approach. Transvascular imaging from the aorta allowed visualization of the various cardiac structures, the neural canal and interspaces, and peritoneal anatomy. Advancement of the transducer to the level of the aortic valve or into the left ventricle yielded images of the cardiac valves and chambers. With transvascular imaging from the inferior and superior vena cava, the aorta, neural canal, pancreas, and liver were well visualized. Intracardiac imaging from the inferior venae cavae and various regions of the right heart, the left heart structures could be visualized. This in vivo feasibility study demonstrates the potential application of transducer-tipped catheters for transvascular and intracardiac imaging.
Women, gender, and world politics: perspectives, policies, and prospects (1995)

Preface Introduction Perspectives Realism, Women, and World Politics by Peter R. Beckman A Feminist Critique of Political Realism by J. Ann Tickner Behavioral Theories: The Science of International Politics and Women by Karen A. Feste Pluralist and Critical Perspectives, Women, and World Politics by Francine D'Amico Feminist Theories: From Women to Gender and World Politics by Sandra Whitworth Third World Feminist Perspectives on World Politics by Hamideh Sedghi Policies Thinking about Women and International Violence by Jean Bethke Elshtain The Cold War and the Feminine Mystique by Rebecca Grant The United Nations and Women's Issues by Margaret E. Galey Women and Development by Nuket Kardam Women and the International Political Economy by Geeta Chowdhry Prospects Creating Change Through Adult Education: Suggestions for Two Priority Areas by Birgit Brock-Utne If Men Are the Problem... by Ralph Pettman Radical Feminism: Alternative Futures by Anne Sisson Runyan Conclusion Selected Bibliography Index
Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae. (1992)

Many cell division cycle (cdc) mutants of Saccharomyces cerevisiae exhibit elevated mitotic loss of pDK243, a 14-kilobase minichromosome with a centromere and one autonomous replicating sequence (ARS). Tandem copies of different ARSs were added to pDK243. The addition of these ARS clusters to pDK243 had no effect on its mitotic loss in cdc7 (protein kinase), cdc9 (DNA ligase), or cdc16 or cdc17 (DNA polymerase) mutants. However, in cdc6 and cdc14 mutants, the mitotic loss of pDK243 with an ARS cluster was suppressed by a factor of 6-8 compared to pDK243 without the cluster. This suppression was dependent upon the number of ARSs in the cluster and the integrity of the ARS consensus sequence in each ARS of the cluster. ARSs are known to be DNA replication origins. Therefore, the suppression of mini-chromosome loss by ARSs in cdc6 and cdc14 mutants suggests that these mutants are defective in the initiation of DNA replication. Since the CDC6 protein appears to act at the G1/S phase transition, the CDC6 protein may be a factor required at the beginning of S phase to initiate DNA replication at origins. In contrast, the CDC14 protein acts after mitosis. We suggest that the CDC14 protein performs a function late in the cell cycle that may be required for efficient initiation of DNA replication during S phase of the next cell cycle.
HISTOLOGICAL CHANGES IN SKELETAL MUSCLE AFTER TEMPORARY INDEPENDENT OCCLUSION OF ARTERIAL AND VENOUS SUPPLY (1978)

In both replantation and transplantation, circulation is restored to ischemic muscle by vascular anastomoses. As a result, the length of time that skeletal muscle will endure ischemia is important to know clinically. Using microsurgical techniques, we shut off the blood supply to the quadriceps femoris muscle in adult Wistar rats--by occluding the artery, the vein, or both for varying time intervals. The muscle was maintained in the animal for 48 hours, and then examined histologically. Our results indicate that the period of warm ischemia should be limited to about one hour, because a longer period of arterial ischemia produces severe histological changes in muscle. The limiting factor seems to be the arterial, rather than the venous supply. The possibility of muscle regeneration after such ischemic insults was not investigated.
SECOND ANTIBODY CHEMICALLY LINKED TO CELLULOSE FOR THE SEPARATION OF BOUND AND FREE HORMONE: AN IMPROVEMENT OVER SOLUBLE SECOND ANTIBODY IN GONADOTROPHIN RADIOIMMUNOASSAY (1976)

Coupling the second antibody to a solid pase (DASP) was found to be a definite improvement over the classical technique of soluble second antibody (DA) separation of bound and free hormone in the radioimmunoassays of gonadotrophins in plasma or in serum. The duration (2.5 to 7.5 min) and the pH (10.5 to 12.5) of the cyanogen bromide activation of microcristalline cellulose did not affect the coupling capacity or the immunoreactivity of the second antibody, nor did it augment aspecific adsorption of free gonadotrophin on the cellulose matrix. Precision of duplicates was comparable for both methods but the accuracy and the detection limit of the solid phase system were higher due to a better separation of bound and free hormone, to the lower blank value and to the absence of aspecific interference of protein concentration. Cost was lower since much less second antibody was needed in the solid phase system than in the soluble system and since the experimental procedures were simplified by the absence of prozoning effect and the solid nature of the cellulose matrix.
[Clinical study of single-dose of recombinant humanized anti-CD3 monoclonal antibody injection in kidney transplant recipients]. (2011)

It is safe to use single-shot OKT3 intravenously in kidney transplant recipients. The recombinant humanized OKT3 may be an effective immunosuppressive agent with milder toxicity for solid organ transplantation.
Growth and Characterization of ZnCdMgSe/ZnCdSe Quantum Wells on InP Substrates for Visible Emitters. (1999)

High-quality lattice-matched quantum well (QW) structures of ZnCdSe/ZnCdMgSe were grown on InP substrates by molecular beam epitaxy. Emission energies from 2.306 to 2.960 eV were measured by low-temperature photoluminescence for samples with QW thicknesses between 5 and 80 A. Bandgap measurements indicate that these structures could be used in entirely lattice-matched blue, green, and yellow diode laser structures. Experimental measurements indicated that these structures have very little strain; hence, these materials could possibly be less prone to degradation than the current II-VI blue-green lasers grown on GaAs substrates.
Plant Storage Lipids (2008)

Abstract Plant storage lipids are major sources of human and livestock nutrition, and of a vast range of renewable industrial products from bioplastics to biofuels. Within plants, storage lipids such as triacylglycerols have several additional nonstorage functions in processes ranging from host–pathogen interactions to abiotic stress responses. Improved knowledge of storage lipid metabolism is being used to create new oil crop varieties and to domesticate new species to supply the ever increasing demand for plant oils.
Learning and expectations in dynamic duopoly behavior (2007)

How two business competitors are influenced by each other is discussed in this paper. Businessman White bases his actions to a large extent on what he expects his competitor, Black, to do. This expectation is based on Black's previous behavior. As White learns to predict Black's behavior more accurately, a process analogous to a marksman “zeroing-in” on a target takes place. The authors offer a dynamic model of this process.
The design of a change notification server for clients of a passive object-oriented database management system (1992)

One way to aid database clients in detecting change to shared data is to provide a notification mechanism which informs clients when the data they have an interest in has changed.Previous research has focused primarily on embedding change notification schemes in a database management system (DBMS).This work explores the feasibility of separating the notification mechanism from the DBMS, thereby allowing an active component to be added to applications which use a passive DBMS.This thesis presents a comprehensive design specification for an object-oriented database management system (OODBMS) change notification server.Objectstore is used as the example underlying OODBMS. \The major contributions of this thesis are its focus on object-oriented (as opposed to relational) data change, the design of a change notification server, and the description of a language used by clients to specify conditions of interest to monitor for change.Further, we present a model of version management, and describe how our notification server can complement an application where clients are versioning data.iii
Cell Size and Water Permeability as Determining Factors for Cell Viability after Freezing at Different Cooling Rates (2004)

This work studied the viabilities of five types of cells (two yeast cells, Saccharomyces cerevisiae CBS 1171 and Candida utilis; two bacterial strains, Escherichia coli and Lactobacillus plantarum; and one human leukemia K562 cell) as a function of cooling rate during freezing. The range of investigated cooling rates extended from 5 to 30,000 degrees C/min. Cell viability was classified into three ranges: (i) high viability for low cooling rates (5 to 180 degrees C/min), which allow cell water outflow to occur completely and do not allow any intracellular crystallization; (ii) low viability for rapid cooling rates (180 to 5,000 degrees C/min), which allow the heat flow to prevail over water outflow (in this case, cell water crystallization would occur as water was flowing out of the cell); (iii) high viability for very high cooling rates (>5,000 degrees C/min), which allow the heat flow to be very rapid and induce intracellular crystallization and/or vitrification before any water outflow from the cell. Finally, an assumption relating cell death to the cell water crystallization as water is flowing out of the cell is made. In addition, this general cell behavior is different for each type of cell and seems to be moderated by the cell size, the water permeability properties, and the presence of a cell wall.
A State‐of‐the‐Art Cyanation of Aryl Bromides: A Novel and Versatile Copper Catalyst System Inspired by Nature (2007)

A general protocol for the cyanation of aryl halides with the nontoxic cyanide source K4[Fe(CN)6] using copper catalysis and a ligand system based on 1-alkylimidazoles is presented. The advantages of this system are the high selectivity, a unique substrate range, easy handling, and inexpensive reagents.
Text classification using multi-word features (2007)

We carried out a series of experiments on text classification using multi-word features. An automated method was proposed to extract the multi-words from text data set and two different strategies were developed to normalize the multi-words into two different versions of multi-word features. After the texts were represented respectively using these two different multi-word features, text classification was conducted in contrast to examine the effectiveness of these two strategies. Also the linear and nonlinear polynomial kernel of support vector machine (SVM) was compared on the performance of text classification task.
Ferromagnetic resonance for the quantification of superparamagnetic iron oxide nanoparticles in biological materials (2010)

The aim of the present work is the presentation of a quantification methodology for the control of the amount of superparamagnetic iron oxide nanoparticles (SPIONs) administered in biological materials by means of the ferromagnetic resonance technique (FMR) applied to studies both in vivo and in vitro. The in vivo study consisted in the analysis of the elimination and biodistribution kinetics of SPIONs after intravenous administration in Wistar rats. The results were corroborated by X-ray fluorescence. For the in vitro study, a quantitative analysis of the concentration of SPIONs bound to the specific AC133 monoclonal antibodies was carried out in order to detect the expression of the antigenic epitopes (CD133) in stem cells from human umbilical cord blood. In both studies FMR has proven to be an efficient technique for the SPIONs quantification per volume unit (in vivo) or per labeled cell (in vitro).
Inflammatory Markers at the Site of Ruptured Plaque in Acute Myocardial Infarction (2005)

Coronary levels of IL-6 and SAA at the site of plaque rupture were increased relative to the systemic circulation, indicating local production of biologically active inflammatory mediators. In contrast, CRP was locally decreased, at least in part by uptake by the phagocyting cells, suggesting a systemic origin of the protein.
Detector development for microPET II: a 1 μl resolution PET scanner for small animal imaging (2001)

We are currently developing a small animal positron emission tomography (PET) scanner with a design goal of 1 microlitre (1 mm3) image resolution. The detectors consist of a 12 x 12 array of 1 x 1 x 10 mm lutetium oxyorthosilicate (LSO) scintillator crystals coupled to a 64-channel photomultiplier tube (PMT) via 5 cm long optical fibre bundles. The optical fibre connection allows a high detector packing fraction despite the dead space surrounding the active region of the PMT. Optical fibre bundles made from different types of glass were tested for light transmission, and also their effects on crystal identification and energy resolution, and compared to direct coupling of the LSO arrays to the PMTs. We also investigated the effects of extramural absorber (EMA) in the fibre bundles. Based on these results, fibre bundles manufactured from F2 glass were selected. We built three pairs of prototype detectors (directly coupled LSO array, fibre bundle without EMA and fibre bundle with EMA) and measured flood histograms, energy resolution, intrinsic spatial resolution and timing resolution. The results demonstrated an intrinsic spatial resolution (FWHM) of 1.12 mm (directly coupled), 1.23 mm (fibre bundle without EMA coupling) and 1.27 mm (fibre bundle with EMA coupling) using an approximately 500 microm diameter Na-22 point source. Using a 330 microm outer diameter steel needle line source filled with F-18, spatial resolution for the detector with the EMA optical fibre bundle improved to 1.05 mm. The respective timing and energy FWHM values were 1.96 ns, 21% (directly coupled), 2.20 ns, 23% (fibre bundle without EMA) and 2.99 ns, 30% (fibre bundle with EMA). The peak-to-valley ratio in the flood histograms was better with EMA (5:1) compared to the optical fibre bundle without EMA (2.5:1), due to the decreased optical cross-talk. In comparison to the detectors used in our current generation microPET scanner, these detectors substantially improve on the spatial resolution, preserve the timing resolution and provide adequate energy resolution for a modern high-resolution animal PET tomograph.
Resonant sensors by silicon micromachining (2002)

Micromachined silicon resonant sensors as infrared sensor, accelerometer, angular rate sensor and AFM probe were developed. The resonator is encapsulated in a vacuum chamber in a glass-silicon structure. Vibrating beams are driven electrostatically and their movements are detected capacitively.
Altered Retinoblastoma (RB) Protein Expression in Human Malignancies (1995)

Dysfunction of the retinoblastoma (RB) gene has implicated not only in the development of retinoblastoma but also in the initiation and/or progression of some of the most common human malignancies. The RB gene encodes a nuclear phosphoprotein of ∼110 kDa. With a modified antigen-retrieval method, several polyclonal and monoclonal anti-RB antibodies are now available for demonstration of RB protein in formalin-fixed, routinely processed pathological specimens. Differing from the uncertainty about p53 immunoreactivity, the immunohistochemical assay for RB protein has proved to be a sensitive and reliable method for detecting RB gene inactivation. Furthermore, although the literature remains controversial, there is growing evidence suggesting that RB protein status is potentially a prognostic marker in urothelial carcinoma and perhaps also in some other types of human neoplasms. More definitive studies, however, must be conducted before the RB gene can be considered a prognostic factor in clinical practice.
1-(2-Alkanamidoethyl)-6-methoxyindole Derivatives:  A New Class of Potent Indole Melatonin Analogues (1997)

A new series of indole melatonin analogues, bearing the amido ethyl side chain attached at the N-1 position of the indole nucleus, were synthesized and tested for their affinity for the melatonin receptor isolated from quail optic tecta in a series of in vitro ligand-binding experiments using 2-[125I]iodomelatonin as the labeled ligand. The biological activity was evaluated using two models: effects on the forskolin-stimulated cAMP accumulation in explants from quail optic tecta and evaluation of the GTP gamma S index derived from competition experiments performed in the absence or presence of GTP gamma S. Compounds 2a and 2k-n, obtained by shifting the methoxy group and the ethylamido side chain from the C-5 and C-3 positions of melatonin to the C-6 and N-1 positions of the indole nucleus, exhibited an affinity similar to that of melatonin itself, as well as full agonist activity. Optimization of the C-2 substituent by introducing Br, phenyl, or COOCH3 (2b-d) resulted in a significantly enhanced affinity (in the picomolar range) and improved agonist biological activity. Compounds lacking the methoxy group and bearing an N-alicyclic group (2h-j) behaved as partial agonists or antagonists.