gebhart/patrepeval huggingface dataset:
<title>Optical tape system: evaluation of recorder and media</title> (1997)

A linear optical tape recorder has been developed and its performance is evaluated. Write-once and rewritable tape samples are tested and on the basis of these results the expected performance of the recorder is concluded. In the recorder data are written and read back with the spot from a single laser that is scanned over the surface with a 10- faced polygon, rotating at up to 3500 Hz. The data density is 1.6 micrometers <SUP>2</SUP>/user-bit, offering 70 Gbyte storage capacity in a VHS-C like cassette. Read and write data rates up to 4.4 and 3.2 Mbytes respectively can be achieved. A novel tape guiding systems winds the tape at a velocity exceeding 20 m/s, offering an average access-time of 1.5 s.
Isolation and characterization of a novel gene induced by 2, 3, 7, 8-tetrachlorodibenzo-<i>p</i>-dioxin in rat liver (1996)

The differential display technique was used to identify genes whose expression was regulated by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Expression of a novel sequence was up-regulated in a dose-dependent fashion in liver of Sprague-Dawley male rats exposed to both chronic and acute treatment with TCDD, as measured by densitometry of Northern blot analyses (P < 0.01). A rapid amplification of cDNA ends (RACE) procedure was used to isolate a 1.8 kb cDNA from a rat liver cDNA preparation. This cloned cDNA, called 25-Dx, was sequenced and found to encode a peptide of 223 amino acids. In control rats, the 25-Dx gene was expressed at high levels in lung and liver. A hydrophobic domain of 14 residues followed by a proline-rich domain, both located in the N-terminal region, showed 71% homology with the transmembrane domain of the precursor for the interleukin-6 receptor and a conserved consensus sequence found in the cytokine/growth factor/prolactin receptor superfamily respectively.
Reaction of carbon-hydrogen bonds in alkanes with bis(diphosphine) complexes of iron (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of carbon-hydrogen bonds in alkanes with bis(diphosphine) complexes of ironMurray V. Baker and Leslie D. FieldCite this: J. Am. Chem. Soc. 1987, 109, 9, 2825–2826Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April 1987https://pubs.acs.org/doi/10.1021/ja00243a046https://doi.org/10.1021/ja00243a046research-articleACS PublicationsRequest reuse permissionsArticle Views840Altmetric-Citations90LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A placebo-controlled study to assess Standardized Field Sobriety Tests performance during alcohol and cannabis intoxication in heavy cannabis users and accuracy of point of collection testing devices for detecting THC in oral fluid (2012)

SFST were mildly sensitive to impairment from cannabis in heavy users. Lack of sensitivity might be attributed to tolerance and time of testing. SFST were sensitive to both doses of alcohol. The Dräger Drug Test® 5000 appears to be a promising tool for detecting THC in oral fluid as far as correct THC detection is concerned.
Solid Contact Ion-Selective Electrodes with a Well-Controlled Co(II)/Co(III) Redox Buffer Layer (2013)

Solid contact ion-selective electrodes (ISEs) typically have an intermediate layer between the ion-selective membrane and the underlying solid electron conductor that is designed to reduce the irreproducibility and instability of the measured electromotive force (emf). Nevertheless, the electrode-to-electrode reproducibility of the emf of current solid contact ISEs is widely considered to be unsatisfactory. To address this problem, we report here a new method of constructing this intermediate layer based on the lipophilic redox buffer consisting of the Co(III) and Co(II) complexes of 1,10-phenanthroline ([Co(phen)3](3+/2+)) paired with tetrakis(pentafluorophenyl)borate as counterion. The resulting electrodes exhibit emf values with an electrode-to-electrode standard deviation as low as 1.7 mV after conditioning of freshly prepared electrodes for 1 h. While many prior examples of solid contact ISEs also used intermediate layers that contained redox active species, the selection of a balanced ratio of the reduced and oxidized species has typically been difficult and was often ignored, contributing to the emf irreproducibility. The ease of the control of the [Co(phen)3](3+)/[Co(phen)3](2+) ratio explains the high emf reproducibility, as confirmed by the emf decrease of 58 mV per 10-fold increase in the ratio of the reduced and oxidized redox buffer species. Use of a gold electrode modified with a self-assembled 1-hexanethiol monolayer as underlying electron conductor suppresses the formation of a water layer and results in an electrode-to-electrode standard deviation of E° of 1.0 mV after 2 weeks of exposure to KCl solution.
Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition (2013)

Inflammation can act as a crucial mediator of epithelial-to-mesenchymal transition (EMT). In this study, we show that oncostatin M (OSM) is expressed in an autocrine/paracrine fashion in invasive breast carcinoma. OSM stimulation promotes spontaneous lung metastasis of MCF-7 xenografts in nude mice. A conspicuous epigenetic transition was induced by OSM stimulation not only in breast cancer cell lines but also in MCF-7 xenografts in nude mice. The expression of miR-200 and let-7 family members in response to OSM stimulation was downregulated in a signal transducer and activator of transcription factor 3 (Stat3)-dependent manner, resulting in comprehensive alterations of the transcription factors and oncoproteins targeted by these microRNAs. Inhibition of Stat3 activation or the ectopic expression of let-7 and miR-200 effectively reversed the mesenchymal phenotype of breast cancer cells. Stat3 promotes the transcription of Lin-28 by directly binding to the Lin-28 promoter, resulting in the repression of let-7 expression and concomitant upregulation of the let-7 target, high-mobility group A protein 2 (HMGA2). Knock down of HMGA2 significantly impairs OSM-driven EMT. Our data indicate that downregulation of let-7 and miR-200 levels initiates and maintains OSM-induced EMT phenotypes, and HMGA2 acts as a master switch of OSM-induced EMT. These findings highlight the importance of Stat3-coordinated Lin-28B-let-7-HMGA2 and miR-200-ZEB1 circuits in the cytokine-mediated phenotypic reprogramming of breast cancer cells.
A high-yield technique for preparing cells fixed in suspension for scanning electron microscopy. (1975)

Human leukocytes fixed in suspension were allowed to settle onto poly-L-lysine-coated glass coverslips and prepared for observation with the scanning electron microscope (SEM). The coverslips were dehydrated in ethanol, critical point dried with CO2, and coated with gold-palladium. With the aid of a locator grid, several fields were photographed with light microscopy after the cells had settled onto the poly-L-lysine-coated coverslips and again after completion of the processing before SEM observation. Quantitative comparison of the number of cells present after settling with the number retained for final viewing with the SEM revealed a cell yield approaching 100%. This simple, reproducible, high-yield technique for processing cells fixed in suspension for SEM prevents changes in surface architecture induced by collecting live cells onto various substrates before fixation and also avoids potentially selective cell losses. Such a technique should allow quantitative correlations between SEM and other morphological and functional parameters.
Contact Type Line Sensor for Examining Surface Topography (1992)

A new sensor has been developed for examining surface topography, especially in a case that is difficult to examine by optical method. This sensor measures the surface topography by bringing a cantilever beams that is similar to a comb into contact with a sample and measuring the deflection of the cantilever as it is scanned across the surface. And this sensor can measure the surface topography at one time scan across the surface. The cantilever beams were processed from phosphor bronze foil. The piezoresisitive effect of silicon thin film was used to sense the deflection of the cantilever. We fabricated the sensor that had 20 and 160 cantilever beams, 200μm pitch, 7mm length, 30μm thickness, and applied to examine the surface topography of a copper plating surface on printed circuit board. We could observe the surface topography with 10μm resolution of depth direction.
Surface acoustic wave tapped correlator using time integration (1975)

A new alternative to the nonlinear delay line convolver is presented, one which has the special advantage of being able to correlate millisecond signals without time inversion. An experimental verification achieved with a simple device is described and the possible use of a more complete system is explained.
Navigation in human-robot and robot-robot interaction using optimization methods (2016)

Human-robot interaction and robot-robot interaction and cooperation in shared spatial areas is a challenging field of research regarding safety, stability and performance. In this paper the collision avoidance between human and robot by extrapolation of human intentions and a suitable optimization of tracking velocities is discussed. Furthermore for robot-robot interactions in a shared area traffic rules and artificial force potential fields and their optimization by market-based approach are applied for obstacle avoidance. For testing and verification, the navigation strategy is implemented and tested in simulation of more realistic vehicles. Extensive simulation experiments are performed to examine the improvement of the traditional potential field (PF) method by the MBO strategy.
A PSK group modem based on digital signal processing: Algorithm, hardware design, implementation and performance (1988)

Abstract A PSK group modem which modulates and demodulates multiple PSK signals en bloc will play an important role in cost‐effective satellite communications systems based on the narrow‐band multicarrier PSK/FDMA technique. This paper describes the development of a PSK group modem, including its algorithm, hardware design and implementation. In the algorithm, PSK signals are efficiently filtered by digital signal processing applied to the digital transmultiplexor. Furthermore, in order to compensate for the difference between the operation timing of the PSK group modem and the symbol timing of each input/output data signal, digital signal processing based on a table‐look‐up method using ROM and a rate‐conversion filter with adaptive weighting are proposed for the modulator and demodulator, respectively. An experimental four‐phase PSK group modem has been developed, and experiments have been conducted under various conditions. The measured performance of the developed hardware is also demonstrated.
ON-CHIP MICROSCALE DISTILLATION FOR ACETONE-WATER SEPARATION (2010)

A silicon-based microscale distillation chip was fabricated consisting of a micro-channel 600 μm in width and 40 cm in length. Micropillars were incorporated in the micro-channel to direct liquid flow from the cooled to the heated end by capillarity. A feed of a 19 mol% acetone-water mixture was separated to 95+ mol% acetone in the distillate and 11 mol% in the bottom stream. This distillation corresponds to three equilibrium stages at total reflux conditions. The purity of the bottom stream could be increased by increasing the distillate flowrate, but at the expense of the distillate stream purity.
Blood–brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis (2004)

Enhanced cerebrovascular permeability and cellular infiltration mark the onset of early multiple sclerosis lesions. So far, the precise sequence of these events and their role in lesion formation and disease progression remain unknown. Here we provide quantitative evidence that blood-brain barrier leakage is an early event and precedes massive cellular infiltration in the development of acute experimental allergic encephalomyelitis (EAE), the animal correlate of multiple sclerosis. Cerebrovascular leakage and monocytes infiltrates were separately monitored by quantitative in vivo MRI during the course of the disease. Magnetic resonance enhancement of the contrast agent gadolinium diethylenetriaminepentaacetate (Gd-DTPA), reflecting vascular leakage, occurred concomitantly with the onset of neurological signs and was already at a maximal level at this stage of the disease. Immunohistochemical analysis also confirmed the presence of the serum-derived proteins such as fibrinogen around the brain vessels early in the disease, whereas no cellular infiltrates could be detected. MRI further demonstrated that Gd-DTPA leakage clearly preceded monocyte infiltration as imaged by the contrast agent based on ultra small particles of iron oxide (USPIO), which was maximal only during full-blown EAE. Ultrastructural and immunohistochemical investigation revealed that USPIOs were present in newly infiltrated macrophages within the inflammatory lesions. To validate the use of USPIOs as a non-invasive tool to evaluate therapeutic strategies, EAE animals were treated with the immunomodulator 3-hydroxy-3-methylglutaryl Coenzyme A reductase inhibitor, lovastatin, which ameliorated clinical scores. MRI showed that the USPIO load in the brain was significantly diminished in lovastatin-treated animals. Data indicate that cerebrovascular leakage and monocytic trafficking into the brain are two distinct processes in the development of inflammatory lesions during multiple sclerosis, which can be monitored on-line with MRI using USPIOs and Gd-DTPA as contrast agents. These studies also implicate that USPIOs are a valuable tool to visualize monocyte infiltration in vivo and quantitatively assess the efficacy of new therapeutics like lovastatin.
Optimal parallel dictionary matching and compression (extended abstract) (1995)

Emerging applications in multi-media and the Human Genome Project require storage and searching of large databases of strings -a task for which parallelism seems the only hope. In this paper, we consider the parallelism in some of the fundamental problems in compressing strings and in matching large dictionaries of patterns against texts. We present the jirst work-optimal algorithms for these well-studied problems including the classical dictionary matching problem, optimal compression with a static dictionary and the universal data compression with dynamic dictionary of Lempel and Ziv. All our algorithms are randomized and they are of the Las Vegas type. Furthermore, they are fast, working in time logarithmic in the input size. Additionally, our algorithms seem suitable for a distributed implementation.
MTA family of coregulators in nuclear receptor biology and pathology (2007)

Nuclear receptors (NRs) rely on coregulators (coactivators and corepressors) to modulate the transcription of target genes. By interacting with nucleosome remodeling complexes, NR coactivators potentiate transcription, whereas corepressors inhibit transcription of the target genes. Metastasis-associated proteins (MTA) represent an emerging family of novel NR coregulators. In general, MTA family members form independent nucleosome remodeling and deacetylation (NuRD) complexes and repress the transcription of different genes by recruiting histone deacetylases onto their target genes. However, MTA1 also acts as a coactivator in a promoter-context dependent manner. Recent findings that repression of estrogen receptor transactivation functions by MTA1, MTA1s, and MTA2 and regulation of MTA3 by estrogen signaling have indicated the significance of these proteins in NR signaling. Here, we highlight the action of MTA proteins on NR signaling and their roles in pathophysiological conditions.
The Research of Intrusion Detection System Based on Fuzzy Method (2004)

This article explains the importance of fuzzy method in intrusion detection after analyzing the disfigurement of current intrusion detection technology, and on this foundation, mainly discusses the application of fuzzy method in intrusion detection, proposes the intrusion detection procedure based on fuzzy method.
Application of periodic operation to maleic anhydride production (1989)

Abstract Two‐step and multi‐step feed composition cycling of the partial oxidation of butadiene to maleic anhydride have been studied. Multi‐step cycles were created by N 2 flushes between steps containing just one reactant. Both production and selectivity to maleic anhydride are decreased over a cycle in this type of periodic operation. Selectivity to furan is increased, however. N 2 flushing concentrates production of maleic anhydride in the butadiene step, which may have process advantages.
Radial Perfectly Matched Layer for the ADI-FDTD Method (2009)

In this letter, a circular absorbing boundary using the radial perfectly matched layer (RPML) is investigated for the alternating-direction-implicit finite-difference time-domain (ADI-FDTD) method. A staircase approach is used to approximate the circular boundary so that it is directly compatible with the commonly used Yee's lattice. The proposed RPML boundary is computationally more efficient than the traditional rectangular PML boundary. It was found that more than 20% of the memory and computation time can be saved by using the proposed method.
pH-dependent cross-linking of catechols through oxidation via Fe<sup>3+</sup>and potential implications for mussel adhesion (2014)

The mussel byssus is a remarkable attachment structure that is formed by injection molding and rapid in-situ hardening of concentrated solutions of proteins enriched in the catecholic amino acid 3,4-dihydroxy-L-phenylalanine (DOPA). Fe<sup>3+</sup>, found in high concentrations in the byssus, has been speculated to participate in redox reactions with DOPA that lead to protein polymerization, however direct evidence to support this hypothesis has been lacking. Using small molecule catechols, DOPA-containing peptides, and native mussel foot proteins, we report the first direct observation of catechol oxidation and polymerization accompanied by reduction of Fe<sup>3+</sup> to Fe<sup>2+</sup>. In the case of the small molecule catechol, we identified two dominant dimer species and characterized their connectivities by nuclear magnetic resonance (NMR), with the C6-C6 and C5-C6 linked species as the major and minor products, respectively. For the DOPA-containing peptide, we studied the pH dependence of the reaction and demonstrated that catechol polymerization occurs readily at low pH, but is increasingly diminished in favor of metal-catechol coordination interactions at higher pH. Finally, we demonstrate that Fe<sup>3+</sup> can induce cross-links in native byssal mussel proteins <i>mefp-1</i> and <i>mcfp-1</i> at acidic pH. Based on these findings, we discuss the potential implications to the chemistry of mussel adhesion.
[Thermal sulfur compounds and esthetic dermatology]. (1989)

Sulfur compounds are involved in a variety of ways in cosmetics and topical surface treatments. The criterium to be kept in mind is the natural skin-friendliness of sulfur (Comel) and the tangible possibility to influence the morphology and function of the skin by sulfur compounds. Thermal sulfur resources--above all fanghi and baregines--appear to have the appropriate properties for use in aesthetic dermatology. Further basic and clinical studies are needed in order to find scientific support for the indications and uses that are at present contemplated with good reason.
Dynamic Modeling and Wear-Based Remaining Useful Life Prediction of High Power Clutch Systems (2005)

A model-based technique is presented for remaining useful life (RUL) prediction of highly dynamic, high-power dry clutch systems by combining physicsbased simulation and wear-prediction models. Primary load and engagement shear drivers (i.e., torque, speed, and clutch surface temperature) are modeled using a first principles approach. An extension of Archard’s law is presented in which life usage is predicted by using multiple stochastic models to determine a wear coefficient for each applicable wear mechanism. These models consider the physical wear process, including debris-particle and protective-layer formation, using parameters such as surface roughness, particle size, and surface temperature. These stochastic variables are evaluated in a probabilistic framework, using statistical methods such as Monte Carlo and importance sampling, which consider both measurement and modeling uncertainty. Confidence interval prognostic results are provided to predict the RUL of the clutch throughout its limited life in near-real time.
Sensitive skin in Europe (2009)

This study is the first study that compares skin sensitivity in European countries. Prevalence is high, but significant differences are noted between these countries. Dermatological antecedents (or treatments?) could be involved in the occurrence of skin sensitivity.
CO<sub>2</sub> Hydrogenation to Formic Acid on Ni(111) (2011)

Periodic, self-consistent, density functional theory (DFT) calculations are employed to study CO2 hydrogenation on Ni(111). CO2 hydrogenation with H adsorbed on the surface and with H absorbed in the subsurface is investigated systematically, and the respective microscopic reaction mechanisms are elucidated. We show that on Ni(111) CO2 hydrogenation to formate intermediate is more favorable than to carboxyl intermediate. The hydrogenation to formate goes through the unidentate structure that rapidly transforms into the bidentate structure. Further hydrogenation from formate to formic acid is energetically more difficult than formate formation. Formation of adsorbed formic acid from adsorbed CO2 and surface hydrogen is an endothermic reaction. Because subsurface H in Ni(111) is substantially less stable compared to surface H, its reaction with adsorbed CO2 to adsorbed formic acid is an exothermic one. Our results may have significant implications for the synthesis of liquid fuels from CO2 and for catalytic hydrogenation reactions in general.