gebhart/patrepeval huggingface dataset:
The operation of the semiconductor-insulator-semiconductor solar cell: Barrier height lowering through interface states (1980)

Previous studies have shown that the characteristics of the semiconductor-insulator-semiconductor (SIS) solar cell can be controlled by the thin interfacial layer. In this paper, we present the results of a theoretical investigation of the role of interface states at the SiO2-Si interface in the ITO-SiO2-Si SIS solar cell. A numerical solution of the governing transport equations yields the dependence of efficiency, short-circuit current, and open-circuit voltage on interface state density. It is shown theoretically that occupied acceptorlike interface state lower the barrier height and thus raise the dark saturation current while lowering the open-circuit voltage. Experimental results are presented which relate the saturation current to the process step which forms the interfacial layer and which support the model.
Relation between dissolved oxygen concentration and ajmalicine production rate in high‐density cultures of <i>Catharanthus roseus</i> (1995)

The relation between dissolved oxygen (DO) and the ajmalicine production rate of Catharanthus roseus was investigated in 15-L tank reactors at constant stirrer speed and gas flow rate. Below a DO concentration of 29% of air saturation the ajmalicine production rate was less than 0.06 micromol/g/d. Above a DO of 43% the ajmalicine production rate was constant at 0.21 micromol/g/d. Between a DO of 29% and 43% there was a strong relation between the ajmalicine production rate and the DO concentration. After a period of at least 12 days at DO <or=29% the culture lacked the ability to adapt to a DO >or=57%. A kinetic equation is proposed for the relation between DO and the specific ajmalicine production rate.
Voltage/Frequency Proportional Control of Stick-Slip Micropositioning Systems (2008)

A new control type for stick-slip micropositioning systems is proposed in this brief: the voltage/frequency (U/f) proportional control. It gives more precise results relatively to the classical control algorithm. It is also an assembling of two classical controllers: the sign and the classical proportional controllers. A high stroke model of a stick-slip micropositioning system is first given. Then, we will theoretically analyze the performances of the closed-loop process with the U/f controller. Finally, we will give some experimental results obtained with different values of the proportional gains.
Electronic tongue: Chemical sensor systems for analysis of aquatic media (2008)

The history of development of “electronic tongue” multisensor systems whose operation is underlain by principles close to those in biological sensory systems was briefly overviewed. The main types of “electronic tongue” systems developed by now were described, along with sensor materials and sensors applied in such systems. The most widespread applications of “electronic tongues” were discussed including those for recognition and classification of liquid media, quantitative analysis of various components in these liquids, smart monitoring of industrial processes, and evaluation of the type and intensity of the flavor of various foodstuffs and drugs.
The national cancer data base report on recent hospital cancer program progress toward complete American joint committee on cancer/TNM staging (1997)

Hospital staging policies were affected by activities of the AJCC, COC, NCDB, clinical protocol procedures, and state policies. The varied completeness of staging at the hospital level by state, region, and type of hospital indicates that the adoption of routine staging is ongoing.
Involvement of cytochromes in the anaerobic biotransformation of tetrachloromethane by Shewanella putrefaciens 200 (1993)

Shewanella putrefaciens 200 is an obligate respiratory bacterium that can utilize a variety of terminal electron acceptors, e.g., NO3-, NO2-, Fe(III), and trimethylamine N-oxide, in the absence of O2. The bacterium catalyzed the reductive transformation of tetrachloromethane (CT) under anaerobic conditions. The only identified product was trichloromethane (CF), but CF production was not stoichiometric. No dichloromethane, chloromethane, or methane was produced. A chloride mass balance indicated that fully dechlorinated products were not formed. Studies with [14C]CT suggested that a portion of the transformed CT reacted with biomass to form unidentified soluble and insoluble products. Intermediate production of a trichloromethyl radical can explain observed product distribution without significant CO2 formation. Evidence suggests that respiratory c-type cytochromes are responsible for the dehalogenation ability of S. putrefaciens 200. Previous growth under microaerobic conditions ([O2], < 2.5 microM) results in (i) a 2.6-fold increase in specific heme c content and (ii) a 2.3-fold increase in specific rates of anaerobic CT transformation. Manipulation of heme content by growth on iron-free medium or medium amended with delta-aminolevulinic acid showed that CT transformation rates increase with increases in specific heme c content. Transformation of CT is inhibited by CO. Dehalogenation studies with periplasmic, cytoplasmic, and membrane fractions indicated that only periplasmic and membrane fractions possessed dehalogenation ability. Cytochromes c were the predominant cytochromes present. Membranes were also found to contain smaller amounts of cytochrome b. Observed CT transformation patterns are consistent with a cometabolic description involving fortuitous CT reduction by reduced c-type cytochromes.
A New Element within the T-Cell Receptor α Locus Required for Tissue-Specific Locus Control Region Activity (1999)

Locus control regions (LCRs) are cis-acting regulatory elements thought to provide a tissue-specific open chromatin domain for genes to which they are linked. The gene for T-cell receptor alpha chain (TCRalpha) is exclusively expressed in T cells, and the chromatin at its locus displays differentially open configurations in expressing and nonexpressing tissues. Mouse TCRalpha exists in a complex locus containing three differentially regulated genes. We previously described an LCR in this locus that confers T-lineage-specific expression upon linked transgenes. The 3' portion of this LCR contains an unrestricted chromatin opening activity while the 5' portion contains elements restricting this activity to T cells. This tissue-specificity region contains four known DNase I hypersensitive sites, two located near transcriptional silencers, one at the TCRalpha enhancer, and another located 3' of the enhancer in a 1-kb region of unknown function. Analysis of this region using transgenic mice reveals that the silencer regions contribute negligibly to LCR activity. While the enhancer is required for complete LCR function, its removal has surprisingly little effect on chromatin structure or expression outside the thymus. Rather, the region 3' of the enhancer appears responsible for the tissue-differential chromatin configurations observed at the TCRalpha locus. This region, herein termed the "HS1' element," also increases lymphoid transgene expression while suppressing ectopic transgene activity. Thus, this previously undescribed element is an integral part of the TCRalphaLCR, which influences tissue-specific chromatin structure and gene expression.
Ebony, a Novel Nonribosomal Peptide Synthetase for β-Alanine Conjugation with Biogenic Amines in Drosophila (2003)

Using Ebony protein either expressed in Escherichia coli or in Schneider S2 cells, we provide evidence for its substrate specificity and reaction mechanism. Ebony activates beta-alanine to aminoacyladenylate by an adenylation domain and covalently attaches it as a thioester to a thiolation domain in a nonribosomal peptide synthetase (NRPS) related mechanism. In a second reaction, biogenic amines act as external nucleophiles on beta-alanyl-S-pantetheine-Ebony, thereby releasing in a fast reaction the dipeptide (peptidoamine) in a process that is novel in higher eucaryotes. Therefore, we define Ebony as a beta-alanyl-biogenic amine synthetase. Insight into the reaction mechanism stems from mutational analysis of an invariant serine that disclosed Ebony as a multienzyme with functional analogy to the starting modules of NRPSs. In light of a putative biogenic amine-deactivating capacity, Ebony function in the nervous system must be reconsidered. We propose that in the Drosophila eye Ebony is involved in the transmission process by inactivation of histamine through beta-alanyl conjugation.
Coadministration of Trametinib and Palbociclib Radiosensitizes KRAS-Mutant Non–Small Cell Lung Cancers <i>In Vitro</i> and <i>In Vivo</i> (2016)

Our findings suggest that MEK inhibitor in combination with CDK4/6 inhibitor has significant anti-KRAS-mutant NSCLC activity and radiosensitizing effect in preclinical models, potentially providing a novel therapeutic strategy for patients with advanced KRAS-mutant NSCLCs.
The effect of alpha blockade on cholesterol regulation <i>in vitro</i> and <i>in vivo</i> (1992)

Conference Article| November 01 1992 The effect of alpha blockade on cholesterol regulation in vitro and in vivo DAPHNE OWENS; DAPHNE OWENS *Department of Biochemistry, Royal College of Surgeons in Ireland Search for other works by this author on: This Site PubMed Google Scholar GERALD H. TOMKIN GERALD H. TOMKIN #Department of Endocrinology, The Adelaide Hospital, Peter St. Dublin 8 Ireland Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1992 Biochemical Society1992 Biochem Soc Trans (1992) 20 (4): 342S. https://doi.org/10.1042/bst020342s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation DAPHNE OWENS, GERALD H. TOMKIN; The effect of alpha blockade on cholesterol regulation in vitro and in vivo. Biochem Soc Trans 1 November 1992; 20 (4): 342S. doi: https://doi.org/10.1042/bst020342s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1992 Biochemical Society1992 Article PDF first page preview Close Modal You do not currently have access to this content.
Silicon Photonics: A Low Cost Integration Platform for Datacom and Telecom Applications (2008)

Si photonics technology as a platform for the realization of cost effective products for telecom and datacom applications is reviewed and recent progress in the area is reported.
A Performance Evaluation of Commercial Fibrinogen Reference Preparations and Assays for Clauss and PT-derived Fibrinogen (2002)

The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays. In a multi-centre study, we investigated fibrinogen assays using various reagents and analysers. Clauss assays generally gave good agreement, although one reagent gave 15-30% higher values in DIC and thrombolysis. Two commercial reference preparations had much lower potencies than the manufacturers declared, and plasma turbidity influenced parallelism in some Clauss assays. PT-Fg assays gave higher values than Clauss and showed calibrant dependent effects, the degree of disparity correlating with calibrant and test sample turbidity. Analyser and thromboplastin dependent differences were noted. The relationship between Clauss and PT-Fg assays was sigmoid, and the plateau of maximal PT-Fg differed by about 2 g/l between reagents. ELISA and immunonephelometric assays correlated well, but with a high degree of scatter. Antigen levels were higher than Clauss, but slightly lower than PT-Fg assays, which appeared to be influenced by degraded fibrinogen. Clauss assays are generally reproducible between centres, analysers and reagents, but PT-Fg assays are not reliable in clinical settings.
A Framework for Joint Wireless Network Virtualization and Cloud Radio Access Networks for Next Generation Wireless Networks (2017)

Wireless network virtualization (WNV) and cloud radio access networks (CRANs) are promising technologies with the potential to be game changing for the fifth generation (5G) wireless networks. In particular, these technologies may have significant impact on the capital expenditure, quality of service provisioning, as well as spectral efficiency in 5G networks. These two technologies are mostly considered separately in previous works. This paper, however, investigates both the gains and requirements of integrating WNV with CRAN. In this paper, we propose WNV schemes for CRAN, where the objective is to maximize the overall system throughput and minimize delay. The proposed schemes are designed to maintain a high level of isolation between mobile network operators (MNOs), which allows the deployment of different scheduling polices by different MNOs, and managing intercell interference, which may lead to significant throughput gain. Overall, the results presented in this paper reveal that a joint CRAN-WNV architecture can be highly efficient when MNOs have unbalanced loads, because MNOs with high loads can seamlessly access the underutilized resources of underloaded MNOs. The throughput gain in unbalanced loads can be as much as 50% using optimal sharing schemes when compared with static sharing, and about 18% when compared with the WNV without CRAN. The resource allocation problem in the joint CRAN-WNV is formulated, and both optimal and low complexity suboptimal solutions are derived. The obtained results show that integrating the two technologies in a joint architecture can significantly improve the network performance. However, reducing the complexity by adopting efficient sharing techniques may have tangible impact on the throughput when compared with optimal sharing.
Stacked elliptical patches for circularly polarized broadband performance (2014)

This DOI was registered to an article that was not presented by the author(s) in person at this conference. As per section 8.2.1.B.13 of IEEE's "Publication Services and Products Board Operations Manual," IEEE has chosen to exclude this article from distribution after the conference. We regret any inconvenience.
The Face and the Possibility of an Ethics of Performance (1999)

The following is the first stage of an investigation into the phenomenology of theatre and its relation to the question of what an ethics of performance might constitute. This is not done to impose some kind of theoretical prescription on what performance should be and do, but is rather an examination of what it already does, and has done, and no doubt will continue to do, as a questioning reflection of interpersonal accountability within human society, between both individuals and groups. I wish to examine two theoretical perspectives that have some important consequences for this issue. In the process I will test these theories against two works of theater, Samuel Beckett's Catastrophe and Ntozake Shange's Spell #7. What compels me to use these two works beyond the easily discernible relevance of the philosophical concepts addressed here, is that each in their own way are themselves theories of the ethical relation in performance. That is, in each the presumed content of the plays determines—or is determined by—the formal selfconsciousness of the context, the site itself, of performance. This investigation emerges from two seemingly different impulses. One comes from my experience of teaching art students who work in intermedia forms—such as performance, installation, conceptual, and computer art—who are in general allergic to most critical theory, but who have found the work of Deleuze and Guattari, especially their book A Thousand Plateaus, to be highly suggestive, if not inspirational, for the creation of art works. Whether or not they understand the overall context and sense of their theory, Deleuze and Guattari's imagery—rhizomes, nomads, war machines, bodies without organs, stratifications, smooth space, and the like—seem to connect intuitively with students's impulses in a time when humanity is radically reconceiving itself and its environment. But beyond its purely libidinal investments as an aesthetics of existence (Foucault), this process of continual fluid redefinition has a crucial bearing on what it means to have agency and also be held accountable for one's actions toward others, which is the fundamental ethical issue at the heart of all political relations to justice, if politics is not simply to be conceived of as a continual state of war of all against all.
Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens (2018)

Viral vectors represent an attractive technology for vaccine delivery. We exploited the integrase defective lentiviral vector (IDLV) as a platform for delivering relevant antigens within the context of the ADITEC collaborative research program. In particular, Influenza virus hemagglutinin (HA) and nucleoprotein (NP) were delivered by IDLVs while H1N1 A/California/7/2009 subunit vaccine (HAp) with or without adjuvant was used to compare the immune response in a murine model of immunization. In order to maximize the antibody response against HA, both IDLVs were also pseudotyped with HA (IDLV-HA/HA and IDLV-NP/HA, respectively). Groups of CB6F1 mice were immunized intramuscularly with a single dose of IDLV-NP/HA, IDLV-HA/HA, HAp alone, or with HAp together with the systemic adjuvant MF59. Six months after the vaccine prime all groups were boosted with HAp alone. Cellular and antibody responses to influenza antigens were measured at different time points after the immunizations. Mice immunized with HA-pseudotyped IDLVs showed similar levels of anti-H1N1 IgG over time, evaluated by ELISA, which were comparable to those induced by HAp + MF59 vaccination, but significantly higher than those induced by HAp alone. The boost with HAp alone induced an increase of antibodies in all groups, and the responses were maintained at higher levels up to 18 weeks post-boost. The antibody response was functional and persistent overtime, capable of neutralizing virus infectivity, as evaluated by hemagglutination inhibition and microneutralization assays. Moreover, since neuraminidase (NA)-expressing plasmid was included during IDLV preparation, immunization with IDLV-NP/HA and IDLV-HA/HA also induced functional anti-NA antibodies, evaluated by enzyme-linked lectin assay. IFNγ-ELISPOT showed evidence of HA-specific response in IDLV-HA/HA immunized animals and persistent NP-specific CD8+ T cell response in IDLV-NP/HA immunized mice. Taken together our results indicate that IDLV can be harnessed for producing a vaccine able to induce a comprehensive immune response, including functional antibodies directed toward HA and NA proteins present on the vector particles in addition to a functional T cell response directed to the protein transcribed from the vector.
Challenges in Efficient Customer Recognition in Contact Centre: State-of-the-Art Survey by Focusing on Big Data Techniques Applicability (2016)

The pulse of today's business processes, competition and technology can be well observed in the increasingly available information companies are confronted with. Particularly, the importance of information leads to big data which makes it even more difficult for companies to manage their information and costumers. Contact centers (CCs) as the main touch point of organizations face the major issues in managing their costumer efficiently. This paper will focus on the role of big data in empowering the current contact centers to shift to the next generation of CCs. Based on the current literature on CCs, four gaps are identified that by addressing them can be the first step in this shift.
Covalent Modification of Proteins and Peptides by the Quinone Methide from 2-<i>tert</i>-Butyl-4,6-dimethylphenol:  Selectivity and Reactivity with Respect to Competitive Hydration (1997)

Covalent modification of cellular nucleophiles by electrophilic metabolites has been shown to be an important pathway in the toxicological activity of many xenobiotic compounds. The p-quinone methide (4-allylidene-2,5-cyclohexadien-1-one, QM) oxidative metabolites of the 4-alkylphenols are a chemical family whose toxicology has been well described. The reactivity of the QM from 2-tert-butyl-4,6-dimethylphenol (BDMP−QM) with respect to hydration has been studied in the 3 < pH < 11 range in order to examine selectivity for competitive reaction with biological nitrogen nucleophiles. The reactivity of BDMP−QM was examined with human hemoglobin A (HbA), angiotensin-III (AIII), amino acids, and amines. Nucleophilic selectivity (kNu/kH2O) and reactivity (kNu) in aqueous solution (7 < pH < 8) for addition of these biological nucleophiles to BDMP−QM demonstrate (i) that adduct formation is competitive with hydration at low nucleophile concentrations and (ii) that proteins, peptides, and tyrosine show enhanced reactivity toward QMs, relative to simple amino acids and related compounds. All adducts were characterized by electrospray mass spectrometry (ESMS). These results provide strong evidence supporting the toxicity of QM metabolites via facile alkylation of nucleophilic nitrogen sites in proteins and peptides, even when present in low concentration in aqueous solution under physiological conditions.
An Overview of the Simultaneous Perturbation Method for Efficient Optimization (1998)

This article is an introduction to the simultaneous perturbation stochastic approximation (SPSA) algorithm for stochastic optimization of multivariate systems. Optimization algorithms play a critical role in the design, analysis, and control of most engineering systems and are in widespread use in the work of APL and other organizations: The future, in fact, will be full of [optimization] algorithms. They are becoming part of almost everything. They are moving up the complexity chain to make entire companies more efficient. They also are moving down the chain as computers spread. (USA Today, 31 Dec 1997) Before presenting the SPSA algorithm, we provide some general background on the stochastic optimization context of interest here
Status of the MEMS industry (2005)

This paper analyzes the current status of the MEMS industry. After the 2000 and 2001 years with high expectation for MEMS devices for the optical telecommunications, followed by the 2002/2003 downturn leading to the closing of more than 100 MEMS fabs worldwide, this industry has come back to a more normal way of working. There are still 10 to 15 companies worldwide which will certainly end their business within 16 months but the overall activity is more stabilized. MEMS markets will reach 5.4 B$ in 2005, with growth rates which are very different if one compares different market segments. The top 30 MEMS manufacturers have a market share of more than 60% of the total market; the remaining 40% is shared by more than 200 companies. Most of the smallest companies have 2 business models: either small companies developing specific processes, with R&D and small volume production, or systems manufacturers with integrated fabs. These fabs are loaded at less than 40% but considered as an enabler for the system business. Many changes are currently appearing: as contract manufacturers become more credible, system manufacturers are looking to externalise their fabrication processes; fabless companies are also finding companies able to produce at the right cost and quality. The fabless business model is now well structured.
Autologous chondrocyte implantation for rheumatoid arthritis of the knee: a case report (2009)

Autologous chondrocyte implantation appears to be effective for treating rheumatoid arthritis of the knee.
Эффективность применения количественного ультразвукового исследования для ранней диагностики и лечения остеопороза (2013)

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