gebhart/patrepeval huggingface dataset:
Productive Programming of GPU Clusters with OmpSs (2012)

Clusters of GPUs are emerging as a new computational scenario. Programming them requires the use of hybrid models that increase the complexity of the applications, reducing the productivity of programmers. We present the implementation of OmpSs for clusters of GPUs, which supports asynchrony and heterogeneity for task parallelism. It is based on annotating a serial application with directives that are translated by the compiler. With it, the same program that runs sequentially in a node with a single GPU can run in parallel in multiple GPUs either local (single node) or remote (cluster of GPUs). Besides performing a task-based parallelization, the runtime system moves the data as needed between the different nodes and GPUs minimizing the impact of communication by using affinity scheduling, caching, and by overlapping communication with the computational task. We show several applications programmed with OmpSs and their performance with multiple GPUs in a local node and in remote nodes. The results show good tradeoff between performance and effort from the programmer.
El reconocimiento de las personas con discapacidad: posibilidad de acceso a los bienes culturales (2010)

Mucho se predica - en el marco de los derechos humanos- acerca del respeto a las diferencias y de la inclusion de quienes tienen capacidades distintas Sin embargo, a mi criterio, tal postura se queda en un reconocimiento ideologico y no legitimo, siguiendo las categorias de “formas ideologicas de reconocimiento o forma de reconocimiento falsa” y formas de reconocimiento no ideologicas o reconocimiento moral” propuestas por Axel Honneth en su texto “El reconocimiento como ideologia”(2006).
Asi, en la actualidad, a las personas con discapacidad no se les brinda una igualdad de oportunidades para una plena participacion e integracion en el desenvolvimiento de su comunidad. 
Ademas, si bien se escribe en distintos tratados internacionales sobre la inclusion como un derecho personalisimo y sobre la aceptacion de las diferencias, a la hora de cumplir con el cupo a nivel laboral, de inscribir a los ninos en escuelas comunes, de adaptar arquitectonicamente las ciudades, de otorgar prestaciones en las obras sociales, el tema dista de ser tan lineal. Y aquello que debiera resultar natural, termina dirimiendose ante la Justicia. 
Por otro lado, el 13 de diciembre de 2006, se aprobo la Convencion Internacional sobre los Derechos de las Personas con Discapacidad. No obstante, si bien este marco legal es muy positivo para redimir los derechos de las personas con discapacidad, es necesario preguntarse por que hizo falta crear esta Convencion, si ya existe un Tratado que determina los Derechos Humanos. 
Este es un trabajo empirico-conceptual que procura analizar como es el real reconocimiento que tienen las personas con discapacidad a institucional . Me centrare, para delimitar el campo, en el reconocimiento que tienen a nivel cultural, especificamente en el acceso a los bienes culturales. Hace dos anos que trabajo en un proyecto que disene para lograr la inclusion de las personas con discapacidad a los Museos, por lo tanto, este analisis hara foco en la real posibilidad de acceso a los Museos de este grupo social. Por otro lado, esta monografia pretende abrir caminos para preguntarse que puede hacer cada uno para modificar practicas y actitudes sociales que excluyen y estigmatizan.
Hybrid Nanogels with Physical and Chemical Cross‐Linking Structures as Nanocarriers (2005)

Polymerizable nanogels were prepared by self-assembly of cholesteryl group-bearing pullulan (CHP) with methacryloyl groups (CHPMA). The CHPMA nanogel was polymerized with 2-methacryloyloxyethyl phosphorylcholine (MPC) by radical polymerization in dilute aqueous solution. The solution properties of the polymers in water were investigated by TEM, SEC-MALS, and fluorescence quenching technique. Monodispersed hybrid nanogels of CHPMA-MPC (CM nanogels) (25-30 nm in radius of gyration) were obtained by using CHPMA nanogel as a seed-nanogel. CM nanogels have a dual cross-linking structure that is physically cross-linked with the cholesteryl groups and chemically cross-linked with the MPC polymer chains. CM nanogels trap heat-denatured carbonic anhydrase B (CAB) and prevent their aggregations. The nanogels maintained the ability of trapping and releasing enzymes by host-guest interaction of cholesteryl group and cyclodextrin.
Structure Transition from Hexagonal Mesostructured Rodlike Silica to Multilamellar Vesicles (2008)

We studied the synthesis of siliceous structures by using a nonionic block copolymer (Pluronic P123) and perfluorooctanoic acid (PFOA) as cotemplates in an acid-catalyzed sol-gel process. Different siliceous structures were obtained through systematically varying the molar ratio (R) of PFOA/P123, and the resultant materials were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, nitrogen sorption analysis, and Fourier-transform infrared spectroscopy. The results are consistent and reveal a structure transition from a highly ordered 2D hexagonal (HEX) mesostructure with a rodlike morphology to multilamellar vesicles (MLVs) with sharp edges when R is increased. The fact that the MLVs are initiated from the end of hexagonally mesostructured rods provides key evidence in such a novel structure transition. Our finding indicates that, at least in our observations, the MLVs are developed gradually from HEX structures, rather than by a direct cooperative self-assembly mechanism. It is suggested that PFOA molecules with rigid fluorocarbon chains closely interact with PEO. This interaction model may well explain (1) the "wall-thicken" effect in HEX mesostructures by enlarging the hydrophilic PEO moiety (R = 0-1.4), (2) the subsequent HEX to multilamellar structure transition by modifying the hydrophilic/hydrophobic volume ratio (R = 1.4-2.8), and (3) the formation of MLVs with sharp edges by increasing the bending energy. This model provides insight into the fabrication of novel porous materials by the use of block copolymers and fluorinated surfactant mixed templates.
Heart Valve Tissue Engineering (2006)

Abstract Valvular heart disease is a slow, debilitating process during which the cardiac valves become stenosed or incompetent and cease to aid in the delivery of blood. Unless the diseased valve is repaired, or replaced with a bioprosthetic or mechanical artificial valve, the patient eventually dies from cardiopulmonary failure. Implanting artificial heart valves involves cutting the chest open, placing the patient on cardiopulmonary bypass, and sewing the prosthetic valve into the aorta. Although the mitral valve also becomes diseased, repair of the mitral valve is now much more common than replacement.
A Synthesis of <i>N</i>-Bridged 5,6-Bicylic Pyridines via A Mild Cyclodehydration Using the Burgess Reagent and Discovery of A Novel Carbamylsulfonylation Reaction (2008)

Cyclodehydration using the Burgess reagent provided a novel approach toward the synthesis of N-bridged 5,6-bicylic pyridines including pyrolo-, imidazo-, and triazolopyridines under mild and neutral conditions. The methodology tolerates acid-sensitive functional groups. A novel addition product was observed between the resulting pyrrolo- or imidazopyridine and an additional equivalent of the Burgess reagent, producing the corresponding sulfonylcarbamate adduct.
Determination and Characterization of Thermostable Esterolytic Activity from a Novel Thermophilic Bacterium Anoxybacillus gonensis A4 (2007)

A novel hot spring thermophile, Anoxybacillus gonensis A4 (A. gonensis A4) was investigated in terms of capability of tributyrin degradation and characterization of its thermostable esterase activity by the hydrolysis of p-nitrophenyl butyrate (PNPB). It was observed that A. gonensis A4 has an esterase with a molecular weight of 62 kDa. The extracellular crude preparation was characterized in terms of substrate specificity, pH and temperature optima and stability, kinetic parameters and inhibition/activation behaviour towards some chemicals and metal ions. Tributyrin agar assay showed that A. gonensis A4 secreted an esterase and V(max) and K(m) values of its activity were found to be 800 U/L and 176.5 microM, respectively in the presence of PNPB substrate. The optimum temperature and pH, for A. gonensis A4 esterase was 60-80 degrees C and 5.5, respectively. Although the enzyme activity was not significantly changed by incubating crude extract solution at 30-70 degrees C for 1 h, the enzyme activity was fully lost at 80 degrees C for same incubation period. The pH-stability profile showed that original crude esterase activity increased nearly 2-fold at pH 6.0. The effect of some chemicals on crude esterase activity indicated that A. gonensis A4 produce an esterase having serine residue in active site and -SH groups were essential for its activity.
Laser Probes for Combustion Chemistry (1980)

The development of a detailed, microscopically based understanding of the chemistry of combustion represents a considerable challenge. This is because so many chemical and physical processes interact together to produce the phenomenon of combustion. What we know as a flame involves a large chemical reaction network through which energy is produced, resulting in steep gradients of both molecular concentrations and temperature; but the reaction rates and mechanistic paths of that network are sensitively dependent on those parameters. Thus, the chemistry is woven inextricably with heat transfer and diffusion of reactive species through the gas flow.
Feedback Control of a Circular Cylinder Wake in Experiment and Simulation (Invited) (2003)

The effect of feedback flow control on the wake of a circular cylinder at a Reynolds number of 100 is investigated in both water tunnel experiment and direct numerical simulation. Our control approach uses a low dimensional model based on proper orthogonal decomposition (POD). The controller applies linear proportional and differential feedback to the estimate of the first POD mode. The range of validity of the POD model is explored in detail. Actuation is implemented as displacement of the cylinder normal to the flow. We demonstrate that the threshold peak amplitude below which the control actuation ceases to be effective is in the order of 5% of the cylinder diameter. The closed loop feedback simulations explore the effect of both fixed phase and variable phase feedback on the wake. While fixed phase feedback is effective in reducing drag and unsteady lift, it fails to stabilize this state once the low drag state has been reached. Variable phase feedback, however, achieves the same drag and unsteady lift reductions while being able to stabilize the flow in the low drag state. In the low drag state, the near wake is entirely steady, while the far wake exhibits vortex shedding at a reduced intensity. We achieved a drag reduction of close to 90% of the vortex-induced drag, and lowered the unsteady lift force by the same amount.
Cmc1p Is a Conserved Mitochondrial Twin CX<sub>9</sub>C Protein Involved in Cytochrome <i>c</i> Oxidase Biogenesis (2008)

Copper is an essential cofactor of two mitochondrial enzymes: cytochrome c oxidase (COX) and Cu-Zn superoxide dismutase (Sod1p). Copper incorporation into these enzymes is facilitated by metallochaperone proteins which probably use copper from a mitochondrial matrix-localized pool. Here we describe a novel conserved mitochondrial metallochaperone-like protein, Cmc1p, whose function affects both COX and Sod1p. In Saccharomyces cerevisiae, Cmc1p localizes to the mitochondrial inner membrane facing the intermembrane space. Cmc1p is essential for full expression of COX and respiration, contains a twin CX9C domain conserved in other COX assembly copper chaperones, and has the ability to bind copper(I). Additionally, mutant cmc1 cells display increased mitochondrial Sod1p activity, while CMC1 overexpression results in decreased Sod1p activity. Our results suggest that Cmc1p could play a direct or indirect role in copper trafficking and distribution to COX and Sod1p.
Video microscopy of fast axonal transport in extruded axoplasm: A new model for study of molecular mechanisms (1985)

The development of AVEC-DIC microscopy and the application of this method to the study of fast axonal transport in isolated axoplasm extruded from the giant axon of the squid Loligo pealei provides a new paradigm for analyzing the intracellular transport of membranous organelles. The size of the axon, the number of transported particles, and the absence of permeability barriers like the plasma membrane in this preparation permit many experiments that are difficult or impossible to perform using other model systems. The use and features of this preparation are described in detail and a number of properties are evaluated for the first time. The process of extrusion is characterized. Particle movement is evaluated both in the interior of extruded axoplasm and along individual fibrils that extend from the periphery of perfused axoplasm. The role of divalent cations, particularly Ca2+, and the effects of elevated Ca2+ on axoplasmic organization and transport are analyzed. A series of pharmacological agents and polypeptides that alter cytoskeletal organization are used to examine the role of microfilaments and microtubules in fast transport. Finally, the effects of depleting ATP and of adding ATP analogues are discussed. The extruded axoplasm preparation is shown to be an invaluable model system for biochemical and pharmacological analyses of the molecular mechanisms of intracellular transport.
Radiation therapy among atomic bomb survivors, Hiroshima and Nagasaki. (1998)

As a follow-up to the two previous surveys of radiation therapy among the atomic bomb survivors, a large-scale survey was performed to document (1) the number of radiation therapy treatments received by the atomic bomb survivors and (2) the types of radiation treatments conducted in Hiroshima and Nagasaki. The previous two surveys covered the radiation treatments among the Radiation Effects Research Foundation Adult Health Study (AHS) population, which is composed of 20,000 persons. In the present survey, the population was expanded to include the Life Span Study (LSS), including 93,611 atomic bomb survivors and 26,517 Hiroshima and Nagasaki citizens who were not in the cities at the times of the bombings. The LSS population includes the AHS population. The survey was conducted from 1981 to 1984. The survey teams reviewed all the medical records for radiation treatments of 24,266 patients at 11 large hospitals in Hiroshima and Nagasaki. Among them, the medical records for radiation treatments of 1556 LSS members were reviewed in detail. By analyzing the data obtained in the present and previous surveys, the number of patients receiving radiation therapy was estimated to be 4501 (3.7%) in the LSS population and 1026 (5.1%) in the AHS population between 1945-1980. During 1945-1965, 98% of radiation treatments used medium-voltage X rays, and 66% of the treatments were for benign diseases. During 1966-1980, 94% of the radiation treatments were for malignant neoplasms. During this period, 60Co gamma-ray exposure apparatus and high-energy electron accelerators were the prevalent mode of treatment in Hiroshima and in Nagasaki, respectively. The mean frequency of radiation therapy among the LSS population was estimated to have been 158 courses/year during 1945-1965 and 110 courses/year during 1966-1980. The present survey revealed that 377 AHS members received radiation therapy. The number was approximately twice the total number of cases found in the previous two surveys. Thus the data on radiation therapy in the AHS members have been updated well by this survey, and will provide information for more precise dose-response analyses of radiation effects in the AHS population. The information extracted from the medical records of the hospitals consisted of hospital names, treatment periods, body sites treated, diagnoses, treatment doses, radiation sources, the field sizes of the exposures and the data for identification of the patients. These data will be essential in estimating the organ doses from scattered radiation and in evaluating the effects of therapeutic radiation.
Thinned stepped frequency waveforms to furnish existing radars with imaging capability (1996)

Introducing imaging capability to an existing radar, even if it is a high RF bandwidth radar, may be difficult, due to limitations on the IF bandwidth, limitations on the pulse repetition frequency and electromagnetic compatibility problems. This paper discusses the use of thinned stepped frequency waveforms, which enable the radar to switch between RF frequencies to provide a synthesized wide RF bandwidth, while the thinning may alleviate some of the constraints imposed on the radar. Random and periodic thinning are discussed in the first part of this paper. However, thinning may cause degradation in image quality, thus an additional technique-Sequence CLEAN deconvolution-is suggested. Sequence CLEAN is an iterative deconvolution algorithm, adopted from the field of radioastronomy, which is capable of resolving close targets in a dense environment, where the system response is heavily affected by high sidelobes.
Emerging Technologies and Cognitive Disability (2004)

Despite the potential of emerging technologies to assist persons with cognitive disabilities, significant practical impediments remain to be overcome in commercialization, consumer abandonment, and in the design and development of useful products. Barriers also exist in terms of the financial and organizational feasibility of specific envisioned products, and their limited potential to reach the consumer market. Innovative engineering approaches, effective needs analysis, user-centered design, and rapid evolutionary development are essential to ensure that technically feasible products meet the real needs of persons with cognitive disabilities. Efforts must be made by advocates, designers and manufacturers to promote better integration of future software and hardware systems so that forthcoming iterations of personal support technologies and assisted care systems technologies do not quickly become obsolete. They will need to operate seamlessly across multiple real-world environments in the home, school, community, and workplace.
Improving Depth Compression in HEVC by Pre/Post Processing (2012)

Depth images have different characteristics from that of color images. They usually have gradual changes within objects while steep changes happen around object boundaries. Compression standards such as H.264/AVC and High Efficiency Video Coding (HEVC) are efficient in dealing with the gradual change regions but usually result in poor performance at edge regions. To facilitate the reuse of the current video coding design and to further improve the depth compression performance, we propose a pre/post processing based compression strategy. By modifying the edge blocks in the depth image to flat blocks, the pre-processed image can be efficiently compressed using existing compression schemes. Meanwhile, those edge blocks are compressed by an edge preserving codec separately. At the decoder, the decoded modified image and the edge blocks will be merged together to form the final reconstructed image. In our simulations, we implement this strategy to HEVC to evaluate the coding performance. Experimental results show the proposed scheme can achieve about 30% - 40% bit savings for Ballet and Break dancers sequences and 60% - 70% bit savings for Kinect captured depth sequences in comparison with HEVC.
Assessment of prebiotic potential of Akpan-yoghurt-like product and effects on the human intestinal microbiota (2015)

The effect of Akpan (yoghurt-like product) consumption on the human intestinal microbiota was examined. The prebiotic potential of Akpan was assessed by in vitro fermentation using, as inocula, individual probiotic strains and faecal samples from three healthy donors. In this latter case, the prebiotic activity was assessed through the quantification of short chain fatty acid (SCFA) production, the evolution of the pH and the evaluation of dynamic bacterial population by fluorescent in situ hybridization (FISH). Results demonstrated that Akpan was metabolized after 44 h of fermentation, exerting a prebiotic effect, similar to that observed for fructooligosaccharides (FOS). All the considered bacterial groups significantly increased after Akpan and FOS fermentation. Under the tested conditions, no significant differences between the SCFA concentration produced by Akpan and FOS after of incubation were detected. Our findings contribute to support the utilization of Akpan as a functional food with potential beneficial effects on gastrointestinal health.
The Casein Kinase II β Subunit Binds to Mos and Inhibits Mos Activity (1997)

Mos is a germ cell-specific serine/threonine kinase and is required for Xenopus oocyte maturation. Active Mos stimulates a mitogen-activated protein kinase (MAPK) by directly phosphorylating and activating MAPK kinase (MKK). We report here that the Xenopus homolog of the beta subunit of casein kinase II (CKII beta) binds to and regulates Mos. The Mos-interacting region of CKII beta was mapped to the C terminus. Mos bound to CKII beta in somatic cells ectopically expressing Mos and CKII beta as well as in unfertilized Xenopus eggs. CKII beta inhibited Mos-mediated MAPK activation in rabbit reticulocyte lysates and repressed MKK activation by v-Mos in a coupled kinase assay. In addition, microinjection of CKII beta mRNA into Xenopus oocytes inhibited progesterone-induced meiotic maturation and MAPK activation, presumably by binding of CKII beta to Mos and thereby inhibiting MAPK activation. Moreover, this inhibitory phenotype could be rescued by another protein that binds to CKII beta, CKII alpha. The ability of ectopic CKII beta to inhibit meiotic maturation and the detection of a complex between endogenous Mos and CKII beta suggest that CKII beta may act as an inhibitor of Mos during oocyte maturation, perhaps setting a threshold beyond which Mos protein must accumulate before it can activate the MAPK pathway.
MV-RNN: A Multi-View Recurrent Neural Network for Sequential Recommendation (2016)

Sequential recommendation is a fundamental task for network applications, and it usually suffers from the item cold start problem due to the insufficiency of user feedbacks. There are currently three kinds of popular approaches which are respectively based on matrix factorization (MF) of collaborative filtering, Markov chain (MC), and recurrent neural network (RNN). Although widely used, they have some limitations. MF based methods could not capture dynamic user's interest. The strong Markov assumption greatly limits the performance of MC based methods. RNN based methods are still in the early stage of incorporating additional information. Based on these basic models, many methods with additional information only validate incorporating one modality in a separate way. In this work, to make the sequential recommendation and deal with the item cold start problem, we propose a Multi-View Recurrent Neural Network (MV-RNN}) model. Given the latent feature, MV-RNN can alleviate the item cold start problem by incorporating visual and textual information. First, At the input of MV-RNN, three different combinations of multi-view features are studied, like concatenation, fusion by addition and fusion by reconstructing the original multi-modal data. MV-RNN applies the recurrent structure to dynamically capture the user's interest. Second, we design a separate structure and a united structure on the hidden state of MV-RNN to explore a more effective way to handle multi-view features. Experiments on two real-world datasets show that MV-RNN can effectively generate the personalized ranking list, tackle the missing modalities problem and significantly alleviate the item cold start problem.