gebhart/patrepeval huggingface dataset:
Herramientas + allá del marco normativo para la rehabilitación sostenible: BREEAM ES método de evaluación de la sostenibilidad de la edificación (2012)

El sector de la edificacion tiene un reto muy importante para incorporar cuestiones de responsabilidad ambiental en la rehabilitacion de edificios. La normativa y la legislacion actuan como catalizadores para que se produzcan innovaciones, se mejore la eficiencia energetica, se reduzcan emisiones, etc. Pero, actualmente la normativa vigente solo regula y fomenta aspectos de eficiencia energetica y no tiene en cuenta otras cuestiones de vital importancia como agua, ecologia, materiales de bajo impacto ambiental, contaminacion etc.
Sin embargo, existen herramientas que van mas alla de la legislacion vigente y fomentan y posibilitan referencias y buenas practicas para promover/rehabilitar edificios sostenibles. Los metodos de evaluacion de la sostenibilidad de la edificacion permiten rehabilitar incorporando cuestiones medioambientales.
El Metodo BREEAM® ES, es un metodo de evaluacion y certificacion de la sostenibilidad de la edificacion, que ademas, constituye una referencia y una guia tecnica para una construccion mas sostenible y que posibilita la comunicacion a terceros de las bondades medioambientales del edificio.
BREEAM® ES es un conjunto de herramientas avanzadas y procedimientos encaminados a medir, evaluar y ponderar los niveles de sostenibilidad de una edificacion, tanto en fase de diseno como en fases de ejecucion y mantenimiento
BREEAM® ES no solo evalua nuevas edificaciones, sino que tambien facilita la evaluacion de rehabilitaciones, ampliaciones e incluso acondicionamiento de edificios existentes. Posibilita introducir aspectos relacionados con la sostenibilidad, como: nuevos materiales y materiales reutilizados, reduccion de las emisiones de NOx, reduccion de la contaminacion acustica y luminica, reciclaje y reutilizacion de agua, etc
Application of Genetic Algorithm in Software Testing (2011)

This paper presents a method for optimizing software testing efficiency by identifying the most critical path clusters in a program. We do this by developing variable length Genetic Algorithms that optimize and select the software path clusters which are weighted in accordance with the criticality of the path. Exhaustive software testing is rarely possible because it becomes intractable for even medium sized software. Typically only parts of a program can be tested, but these parts are not necessarily the most error prone. Therefore, we are developing a more selective approach to testing by focusing on those parts that are most critical so that these paths can be tested first. By identifying the most critical paths, the testing efficiency can be increased.
Solubility of xenon in liquid <i>n</i>-alkanes: Temperature dependence and thermodynamic functions (1982)

Measurements of the Ostwald solubility as a function of temperature L(T) are reported for 133Xe gas in liquid n-alkanes. All the alkanes from n-C5H12 through n-C20H42 were investigated and the temperatures ranged from 10.0 to 50.0 °C. The experimental method is recently developed and has some unique aspects. From the temperature dependent results the chemical potential Δμ20(T), the enthalpy ΔH̄20, and the entropy ΔS̄20 of solution were determined. Values for Δμ20(T) ranged from 2546 cal/mol for n-C7H16 at 50.0 °C to 1811 cal/mol for n-C14H30 at 10.0 °C. The range of ΔH̄20 was from −2818 cal/mol for n-C5H12 to −2117 cal/mol for n-C20H42, and the corresponding range in ΔS̄20 was −16.90 to −13.58 cal/mol K. A Barclay–Butler plot of the thermodynamic functions and a plot of the dependence of solubility on the Hildebrand solubility parameter for this system are displayed. All of the data obtained in this experiment may be given to better than 0.8% by the empirical relation Δμ20=−RT ln x2=−0.0637nT+2.575×10−2T2, in which x2 is the mole fraction of solute in the solvent at 1 atm partial pressure and T is the absolute temperature. Because the solute is an inert monatomic gas and the solvents are a single homologous series of nonpolar liquids, the results show some interesting simple physical interpretation.
Comparison of Effects of Morning Versus Evening Administration of Ezetimibe/Simvastatin on Serum Cholesterol in Patients with Primary Hypercholesterolemia (2011)

Morning administration of ezetimibe/simvastatin 10 mg/20 mg is noninferior to evening administration with respect to LDL-C-lowering ability.
Tellurite photonic crystal fiber (2003)

We report the fabrication of a Tellurite photonic crystal fiber, and demonstrate its waveguiding properties. The measured minimum loss is 2.3 dB/m at a wavelength of 1055 nm. The fiber supports several modes, but in practice just the fundamental mode can be used. We have observed strong stimulated Raman scattering in a fiber with an effective area Aeff=21.2microm2, using sub-ns, ~ 1 microJ pump pulses at 1064.
PROPOSAL OF AN ALGORITHM FOR TRANSMISSION AND CACHE OF LOCATION DEPENDENT DATA FOR IN-VEHICLE COMPUTER SYSTEMS (1999)

Computer systems equipped in vehicles, such as AutoPC and Connected Car PC, have been proposed recently to contribute to improving road transport safety, efficiency and comfort. These systems generally provide drivers with some information through relatively slow cellular phone networks. While high performance digital broadcasting for mobile users will be available in a few years, the drawback of broadcast delivery methods is the need for users to wait for the required data items to appear on the broadcast channel. In this paper, an algorithm is proposed for transmitting and caching location dependent data that are usually managed on in-vehicle computer systems, through multiple communication media, such as digital TV / radio broadcasting, dedicated short range communication (DSRC), advanced cellular phone networks, and so on. The algorithm enables users immediate access to required data, and keeps the memory usage small to cache data. (A*) For the covering abstract see ITRD E110327.
Traceability – Problem or Opportunity? (1993)

Changes in legislation, congestion problems and the continuing drive to improve supply chain profitability are being addressed by new technologies. The part of the logistics cycle that is now the focus of attention is supply chain traceability, particularly the tracking and traceability of transport, personnel and goods. The new technologies that are being brought to bear on supply chain traceability include, Mobile Data, Automatic Vehicle Identification (AVL), Global Positioning Systems (GPS), consignment tracking, etc. These technologies have now reached maturity in their technical development and are being effectively incorporated into business processes. Provides an overview of the technical status and future prospects of these technological developments and argues the business case for and against traceability. Also assesses the key market sectors in which these technologies will have an impact and suggests that a “building bricks” approach is taken to incorporating the technologies into re‐engineered business processes.
Assessing soil bacterial community and dynamics by integrated high-throughput absolute abundance quantification (2018)

Microbial ecological studies have been remarkably promoted by the high-throughput sequencing approach with explosive information of taxonomy and relative abundance. However, relative abundance does not reflect the quantity of the microbial community and the inter-sample differences among taxa. In this study, we refined and applied an integrated high-throughput absolute abundance quantification (iHAAQ) method to better characterize soil quantitative bacterial community through combining the relative abundance (by high-throughput sequencing) and total bacterial quantities (by quantitative PCR). The proposed iHAAQ method was validated by an internal reference strain EDL933 and a laboratory strain WG5. Application of the iHAAQ method to a soil phenanthrene biodegradation study showed that for some bacterial taxa, the changes of relative and absolute abundances were coincident, while for others the changes were opposite. With the addition of a microbial activity inhibitor (NaN<sub>3</sub>), the absolute abundances of soil bacterial taxa, including several dominant genera of <i>Bacillus</i>, <i>Flavobacterium</i>, and <i>Paenibacillus</i>, decreased significantly, but their relative abundances increased after 28 days of incubation. We conclude that the iHAAQ method can offer more comprehensive information to reflect the dynamics of soil bacterial community with both relative and absolute abundances than the relative abundance from high-throughput sequencing alone.
Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified (1988)

The insulin-like growth factor II (IGF-II) is a polypeptide hormone with structural homologies to insulin and insulin-like growth factor I (IGF-I). In contrast to these other hormones, the in vivo function of IGF-II is not known. Although IGF-II can stimulate a broad range of biological responses in isolated cells, these responses have usually been found to be mediated by the insulin and IGF-I receptors. Recently, the receptor for IGF-II was found to also be the receptor for mannose-6-phosphate. Since this latter receptor has been implicated in targeting of lysosomal enzymes, the question is now raised of whether the same protein can also mediate metabolic responses to IGF-II.
Design of a visible-light-communication enhanced WiFi system (2015)

Visible light communication (VLC) has wide unlicensed bandwidth, enables communication in radio frequency (RF) sensitive environments, realizes energy-efficient data transmission, and has the potential to boost the capacity of wireless access networks through spatial reuse. On the other hand, WiFi provides more coverage than VLC and does not suffer from the likelihood of blockage due to the light of sight (LOS) requirement of VLC. In order to take the advantages of both WiFi and VLC, we propose and implement two heterogeneous systems with Internet access. One is the hybrid WiFi-VLC system, utilizing unidirectional VLC channel as downlink and reserving the WiFi back-channel as uplink. The asymmetric solution resolves the optical uplink challenges and benefits from the full-duplex communication based on VLC. To further enhance the robustness and increase throughput, the other system is presented, in which we aggregate WiFi and VLC in parallel by leveraging the bonding technique in Linux operating system. Online experiment results reveal that the hybrid system outperforms the conventional WiFi for the crowded environments in terms of throughput and web page loading time; and also demonstrate the further improved performance of the aggregated system when considering the blocking duration and the distance between access point and user device.
ANTI-INFLAMMATORY EFFECTS OF THEOPHYLLINE: MODULATION OF IMMUNE FUNCTIONS DURING MURINE LEUKEMIA VIRUS INFECTION (2001)

LP-BM5 murine leukemia virus induces immune dysfunction leading to B cell leukemia and murine AIDS with cytokine dsyregulation. Theophylline induces apoptosis of leukemia cells in humans. Therefore the effects of theophylline on immune dysfunction in a murine model of leukemia were investigated. C57BL/6 mice consumed drinking water containing 0.3% theophylline beginning 2 weeks after murine retrovirus infection for 4 months. Theophylline largely prevented the retrovirus induced splenomagaly, lymphodenopathy, reduction in B and T cell proliferation, and suppression of Thl cytokines (IL-2) secretion. It also suppressed Th2 cytokine (IL-4, TNF-alpha, and IL-10) production, which was otherwise stimulated by retrovirus infection. These data suggest that immune dysfunction, induced by murine retrovirus infection, was largely prevented by theophylline treatment.
Characterization of physicochemical forces involved in adhesion of Listeria monocytogenes to surfaces (1991)

This study investigated the physicochemical forces involving the adhesion of Listeria monocytogenes to surfaces. A total of 22 strains of L. monocytogenes were compared for relative surface hydrophobicity with the salt aggregation test. Cell surface charges and hydrophobicity of L. monocytogenes Scott A were also determined by electrophoretic mobility, hydrophobic-interaction chromatography, and contact angle measurements. Electrokinetic measurements indicated that the strain Scott A has a negative electrophoretic mobility. Physicochemical characterization of L. monocytogenes by various methods indicates that this microorganism is hydrophilic. All L. monocytogenes strains tested with the salt aggregation test method aggregated a at very high ammonium sulfate molarities. The hydrophobicity-interaction chromatography results show that L. monocytogenes Scott A cells do not adhere to octyl-Sepharose unless the pH is low. Results from contact angle measurements showed that the surface free energy of strain Scott A was 65.9 mJ.m-2, classifying this microorganism as a hydrophilic bacterium. In addition, the interfacial free energy of adhesion of L. monocytogenes Scott A estimated for polypropylene and rubber was lower than that for glass and stainless steel. However, these theoretical implications could not be correlated with the attachment capabilities of L. monocytogenes.
Improve image annotation by using Markov model (2010)

In this paper, we propose a novel image annotation algorithm based on Markov model. This algorithm treats each candidate keyword as a state in Markov chain, and implements image annotation by estimating the probability of Markov transition. On one aspect, compared with classical algorithms, the proposed algorithm stops making the assumption that each keyword is independent to each other; instead, they are related to the existed keywords; On the other hand, not only considering correlation between keywords that improves results of image annotation, but our proposed approach also takes image visual content into account. Experimental results on the typical Corel dataset demonstrate the effectiveness and the increasing annotation precision of our proposed algorithm.
Optogenetic Stimulation of the M2 Cortex Reverts Motor Dysfunction in a Mouse Model of Parkinson's Disease (2019)

Neuromodulation of deep brain structures (deep brain stimulation) is the current surgical procedure for treatment of Parkinson's disease (PD). Less studied is the stimulation of cortical motor areas to treat PD symptoms, although also known to alleviate motor disturbances in PD. We were able to show that optogenetic activation of secondary (M2) motor cortex improves motor functions in dopamine-depleted male mice. The stimulated M2 cortex harbors glutamatergic pyramidal neurons that project to subcortical structures, critically involved in motor control, and makes synaptic contacts with dopaminergic neurons. Strikingly, optogenetic activation of M2 neurons or axons into the dorsomedial striatum increases striatal levels of dopamine and evokes locomotor activity. We found that dopamine neurotransmission sensitizes the locomotor behavior elicited by activation of M2 neurons. Furthermore, combination of intranigral infusion of glutamatergic antagonists and circuit specific optogenetic stimulation revealed that behavioral response depended on the activity of M2 neurons projecting to SNc. Interestingly, repeated M2 stimulation combined with l-DOPA treatment produced an unanticipated improvement in working memory performance, which was absent in control mice under l-DOPA treatment only. Therefore, the M2-basal ganglia circuit is critical for the assembly of the motor and cognitive function, and this study demonstrates a therapeutic mechanism for cortical stimulation in PD that involves recruitment of long-range glutamatergic projection neurons.<b>SIGNIFICANCE STATEMENT</b> Some patients with Parkinson's disease are offered treatment through surgery, which consists of delivering electrical current to regions deep within the brain. This study shows that stimulation of an area located on the brain surface, known as the secondary motor cortex, can also reverse movement disorders in mice. Authors have used a brain stimulation technique called optogenetics, which allowed targeting a specific type of surface neuron that communicates with the deep part of the brain involved in movement control. The study also shows that a combination of this stimulation with drug treatment might be useful to treat memory impairment, a kind of cognitive problem in Parkinson's disease.
Numerical chromosomal instability mediates susceptibility to radiation treatment (2015)

The exquisite sensitivity of mitotic cancer cells to ionizing radiation (IR) underlies an important rationale for the widely used fractionated radiation therapy. However, the mechanism for this cell cycle-dependent vulnerability is unknown. Here we show that treatment with IR leads to mitotic chromosome segregation errors in vivo and long-lasting aneuploidy in tumour-derived cell lines. These mitotic errors generate an abundance of micronuclei that predispose chromosomes to subsequent catastrophic pulverization thereby independently amplifying radiation-induced genome damage. Experimentally suppressing whole-chromosome missegregation reduces downstream chromosomal defects and significantly increases the viability of irradiated mitotic cells. Further, orthotopically transplanted human glioblastoma tumours in which chromosome missegregation rates have been reduced are rendered markedly more resistant to IR, exhibiting diminished markers of cell death in response to treatment. This work identifies a novel mitotic pathway for radiation-induced genome damage, which occurs outside of the primary nucleus and augments chromosomal breaks. This relationship between radiation treatment and whole-chromosome missegregation can be exploited to modulate therapeutic response in a clinically relevant manner.
Unsupervised Learning of Long-Term Motion Dynamics for Videos (2017)

We present an unsupervised representation learning approach that compactly encodes the motion dependencies in videos. Given a pair of images from a video clip, our framework learns to predict the long-term 3D motions. To reduce the complexity of the learning framework, we propose to describe the motion as a sequence of atomic 3D flows computed with RGB-D modality. We use a Recurrent Neural Network based Encoder-Decoder framework to predict these sequences of flows. We argue that in order for the decoder to reconstruct these sequences, the encoder must learn a robust video representation that captures long-term motion dependencies and spatial-temporal relations. We demonstrate the effectiveness of our learned temporal representations on activity classification across multiple modalities and datasets such as NTU RGB+D and MSR Daily Activity 3D. Our framework is generic to any input modality, i.e., RGB, depth, and RGB-D videos.
Circadian Metabolomics in Time and Space (2017)

Circadian rhythms are widely known to govern human health and disease, but specific pathogenic mechanisms linking circadian disruption to metabolic diseases are just beginning to come to light. This is thanks in part to the development and application of various "omics"-based tools in biology and medicine. Current high-throughput technologies allow for the simultaneous monitoring of multiple dynamic cellular events over time, ranging from gene expression to metabolite abundance and sub-cellular localization. These fundamental temporal and spatial perspectives have allowed for a more comprehensive understanding of how various dynamic cellular events and biochemical processes are related in health and disease. With advances in technology, metabolomics has become a more routine "omics" approach for studying metabolism, and "circadian metabolomics" (i.e., studying the 24-h metabolome) has recently been undertaken by several groups. To date, circadian metabolomes have been reported for human serum, saliva, breath, and urine, as well as tissues from several species under specific disease or mutagenesis conditions. Importantly, these studies have consistently revealed that 24-h rhythms are prevalent in almost every tissue and metabolic pathway. Furthermore, these circadian rhythms in tissue metabolism are ultimately linked to and directed by internal 24-h biological clocks. In this review, we will attempt to put these data-rich circadian metabolomics experiments into perspective to find out what they can tell us about metabolic health and disease, and what additional biomarker potential they may reveal.
Abnormal apical cell membrane in cystic fibrosis respiratory epithelium. An in vitro electrophysiologic analysis. (1987)

The transepithelial chloride permeability of airway and sweat ductal epithelium has been reported to be decreased in patients with cystic fibrosis (CF). In the present study, we investigated whether the airway epithelial defect was in the cell path by characterizing the relative ion permeabilities of the apical membrane of respiratory epithelial cells from CF and normal subjects. Membrane electric potential difference (PD) and the responses to luminal Cl- replacement, isoproterenol, and amiloride were measured with intracellular microelectrodes. The PD across the apical barrier was smaller for CF (-11 mV) than normal (-29 mV) epithelia whereas the PD across the basolateral barrier was similar, (-26 and -34 mV respectively). In contrast to normal nasal epithelium, the apical membrane in CF epithelia was not Cl- permselective and was not responsive to isoproterenol. Amiloride, a selective Na+ channel blocker, induced a larger apical membrane hyperpolarization and a greater increase in transepithelial resistance in CF epithelia. Both reduced apical cell membrane Cl- conductance and increased Na+ conductance appear to contribute to the abnormal function of respiratory epithelia of CF patients.
Dimensões institucionais da gestão escolar (2020)

Neste artigo, partimos da premissa de que a gestão escolar é uma dimensão central do processo de construção da escola pública democrática, e, por conseguinte, da consolidação da transição democrática brasileira. Essa premissa nos leva a sustentar que a gestão escolar deve participar ativamente de processos sociológicos normalmente tomados como dados por ela, a saber: a construção social do aluno, em sua grande maioria oriundo de famílias com baixa cultura escolar; a formação de um professor capacitado para lidar com esse tipo de aluno; a transformação da família popular em responsável pedagógica; e, ainda, o trabalho de coordenação da energia da sociedade civil voltada para a educação escolar. Ao final do artigo, afirmamos que admitir que a gestão escolar deve atuar nessas esferas não significa dizer que elas são de sua responsabilidade exclusiva, mas evidencia que a reforma da escola não poderá ser realizada sem sua plena participação.
A review of the timing and filtering technologies in smartphones (2016)

The explosive growth of the smartphone market especially in supporting LTE (Long Term Evolution) to meet continuous demand for more and faster data transfer has drawn interest from many who want to know how timing and filtering components are used in smartphones to support the crowded spectrum and their future market opportunities. Known to many, the timing and filtering functions in smartphones have been diligently supported for many years by some “physically moving” electromechanical components based on piezoelectric materials-quartz-based crystal, lithium tantalate- and lithium niobate-based surface acoustic wave (SAW) RF filter, and aluminum nitride-based bulk acoustic wave (BAW) RF filter. This paper reviews the current timing and filtering technologies in smartphones and discusses the possible trends.