gebhart/patrepeval huggingface dataset:
Extraction of (key,value) pairs from unstructured ads (2014)

In this paper, we focus on the problem of extracting structured labeled data from short unstructured adpostings from online sources like Craigslist, where ads are posted on various topics, such as job postings, rentals, car sales etc. A fundamental challenge in addressing this problem is that most ad-postings are highly unstructured, short-text postings written in an informal manner with no inherent grammar or welldefined dictionary. In this paper, we propose unsupervised and supervised algorithms for extracting structured data from unstructured ads in the form of (key, value) pairs where the keys naturally represent topicspecific features in the ads. The unsupervised algorithm is centered around building an affinity graph, using the words from a topic-specific corpus of such ads where the edge weights represent affinities between words; the (key, value) extraction algorithm identifies specific groups of words in the affinity graph corresponding to different classes of key attributes. The supervised algorithm uses a Conditional Random Field based training algorithm to identify specific structured (key, value) pairs based on pre-defined topic-specific structural data representations of ads. Based on a corpus of car and apartment ad-postings from Craigslist, the unsupervised algorithm reported an accuracy of 67.74% and 68.74% for car and apartment ads respectively. The supervised algorithm demonstrated an improved performance with accuracies of 74.07% and 72.59% respectively.
A molybdenum based metallomicellar catalyst for controlled and selective sulfoxidation reactions in aqueous medium (2014)

A surfactant based molybdenum system that exhibits catalytic activity for sulfoxidation reactions of various organic sulfides in aqueous medium has been developed and comprehensively characterized using IR, XRD, NMR, ESI-MS, DLS and TEM. The catalyst showcases remarkable selectivity for the preparation of both sulfoxides and sulfones in the range of good to excellent yields. Furthermore, the catalyst showed a high degree of tolerance towards various sensitive functional groups such as hydroxyl, acetal, aldehyde, amine, imine, oxime, cyano and alkene.
Granulocyte Neutral Proteases and Pseudomonas Elastase as Possible Causes of Airway Damage in Patients with Cystic Fibrosis (1984)

We studied the possible role of granulocyte neutral proteases as mediators of airway destruction in patients with cystic fibrosis (CF) who were infected with Pseudomonas aeruginosa. We measured the enzymatic activities of bronchial secretions on purified radioactively labeled complement component three (C3), elastin, and a granulocyte elastase-specific substrate. Bronchial secretions from 18 patients with CF who were infected with P aeruginosa had a significantly higher mean value for C3 cleaving, elastolytic, and granulocyte elastase-like activity than did two control groups. High enzymatic activities were observed in patients with CF who have advanced bronchial disease (that had been determined by a clinical scoring system). Kinetics of proteolysis of radioactively labeled C3 and inhibition profiles of the activities of the three enzymatic activities studied suggest that they are mainly derived from granulocytes. In addition, 20 of 31 strains of P aeruginosa isolated from patients with CF inactivated purified alpha 1-antiprotease in vitro. We postulate that granulocyte neutral proteases and P aeruginosa may act synergistically in the airways of patients with CF and may contribute to the destruction of elastin and inactivation of C3.
Detecting signals buried in noise via nanowire transistors using stochastic resonance (2012)

We demonstrate stochastic resonance (SR), which takes advantage of noise to detect a weak signal, using a field-effect transistor (FET). An FET's structure composed of a nanowire channel enables current characteristics to show strong nonlinearity, which overcomes thermal limitation, and dynamic bistability, both of which boost an effect of SR and silhouette noise from noise. Moreover, the dynamic bistability enables SR effect to be enhanced by adding common noise to multiple FETs. The FET providing such unique characteristics opens the way to use SR for practical applications.
Urocortin 2 sustains haemodynamic and renal function during introduction of beta-blockade in experimental heart failure (2011)

Ucn2 coupled with beta-blockade in experimental heart failure improves CO and MAP, sustains HR, reduces peripheral resistance, LAP and aldosterone and augments renal function. These results suggest a role for Ucn2 as a short-term parenteral therapy in the initial stages of managing ADHF that improves tolerance to introduction of beta-blockers.
Digital low-pass filtering using the discrete Hilbert transform (1978)

A matrix formulation for a digital low-pass filter, alternative to that given by Sabri and Steenaart, is presented. It is shown that the new formulation offers computational advantages and has better noise performance.
Light Extraction: Light Extraction of Organic Light Emitting Diodes by Defective Hexagonal‐Close‐Packed Array (Adv. Funct. Mater. 16/2012) (2012)

On page 3454, Franky So and co-workers report the preparation of defective hexagonal-close-packed arrays to extract the waveguide modes trapped in an organic light-emitting diode. The broadening of the periodicity and the lack of long-range ordering in the defective array pattern allow effective extraction of the waveguide modes over all emission wavelengths and angles, resulting in non-directional light emission with insignificant spectral changes.
Ultra-high performance wearable thermoelectric coolers with less materials (2019)

Thermoelectric coolers are attracting significant attention for replacing age-old cooling and refrigeration devices. Localized cooling by wearable thermoelectric coolers will decrease the usage of traditional systems, thereby reducing global warming and providing savings on energy costs. Since human skin as well as ambient air is a poor conductor of heat, wearable thermoelectric coolers operate under huge thermally resistive environment. The external thermal resistances greatly influence thermoelectric material behavior, device design, and device performance, which presents a fundamental challenge in achieving high efficiency for on-body applications. Here, we examine the combined effect of heat source/sink thermal resistances and thermoelectric material properties on thermoelectric cooler performance. Efficient thermoelectric coolers demonstrated here can cool the human skin up to 8.2 °C below the ambient temperature (170% higher cooling than commercial modules). Cost-benefit analysis shows that cooling over material volume for our optimized thermoelectric cooler is 500% higher than that of the commercial modules.
Fluorescent Proton Sensors Based on Energy Transfer (2011)

Photophysical data and orbital energy levels (from electrochemistry) were compared for molecules with the same BODIPY acceptor part (red) and perpendicularly oriented xanthene or BODIPY donor fragments (green). Transfer of energy, hence the photophysical properties of the cassettes, including the pH dependent fluorescence in the xanthene-containing molecules, correlates with the relative energies of the frontier orbitals in these systems. Intracellular sensing of protons is often achieved via sensors that switch off completely at certain pH values, but probes of this type are not easy to locate inside cells in their "off-state". A communication from these laboratories (J. Am. Chem. Soc., 2009, 131, 1642-3) described how the energy transfer cassette 1 could be used for intracellular imaging of pH. This probe is fluorescent whatever the pH, but its exact photophysical properties are governed by the protonation states of the xanthene donors. This work was undertaken to further investigate correlations between structure, photophysical properties, and pH for energy transfer cassettes. To achieve this, three other cassettes 2-4 were prepared: another one containing pH-sensitive xanthene donors (2) and two "control cassettes" that each have two BODIPY-based donors (3 and 4). Both the cassettes 1 and 2 with xanthene-based donors fluoresce red under slightly acidic conditions (pH < ∼6) and green when the medium is more basic (>∼7), whereas the corresponding cassettes with BODIPY donors give almost complete energy transfer regardless of pH. The cassettes that have BODIPY donors, by contrast, show no significant fluorescence from the donor parts, but the overall quantum yields of the cassettes when excited at the donor (observation of acceptor fluorescence) are high (ca. 0.6 and 0.9). Electrochemical measurements were performed to elucidate orbital energy level differences between the pH-fluorescence profiles of cassettes with xanthene donors, relative to the two with BODIPY donors. These studies confirm energy transfer in the cassettes is dramatically altered by analytes that perturb relative orbital levels. Energy transfer cassettes with distinct fluorescent donor and acceptor units provide a new, and potentially useful, approach to sensors for biomedical applications.
Positioning in Indoor Mobile Systems (2010)

At present times people travel far greater distances on daily bases than our not so distanced ancestors had travelled in their lifetimes. Technological revolution had brought human race in an excited state and steered it towards globalization. Nevertheless, the process of globalization is not all about new and faster means of transportation or about people covering superior distances. Immense amount of information, ubiquitous and easily accessible, formulate the essence of this process. Consequently, ways through which the information flows are getting too saturated for free usage so, for example, frequency spectrum had become a vital natural resource with a price tagged on its lease. However, the price of not having the information is usually much higher. By employing various wireless technologies we are trying to make the most efficient use of frequency spectrum. These new technologies have brought along the inherent habit of users to be able to exchange information regardless of their whereabouts. Higher uncertainty of the user's position has produced increase in the amount of information contained in its position. As a result, services built on the location awareness capabilities of the mobile devices and/or networks, usually referred to as Location Based Services (LBS, also referred to as LoCation Services -LCS), have been created. Example of services using the mobile location can be: location of emergency calls, mobile yellow pages, tracking and monitoring, location sensitive billing, commercials, etc. With the development of these services, more efforts are being pushed into producing the maximum of location-dependent information from a wireless technology. Simply, greater the amount of information available -more accurate the location estimate is. Whereas in outdoor environment the satellite-based positioning techniques, such as the Global Positioning System (GPS), have considerable advantages in terms of accuracy, the problem of position determination in an indoor environment is much farther from having a unique solution. Cellular-based, Computer vision, IrDA (Infrared Data Association), ultrasound, satellite-based (Indoor GPS) and RF (Radio Frequency) systems can be used to Sometimes, in literature, the words position and location have different meaning. Most often, position translates to the set of numerical values (such as geographical coordinates) which describe the user's placement, whereas the location usually refers to the descriptive information depicting the user's whereabouts (such as Picadilly Circus, London, UK). Nevertheless, this work treats both words interchangeably.
Supplement multi-media services for ACeS (2003)

Asia Cellular Satellite System (ACeS) is a $900 million fully financed project that uses two A2100AX geo satellites manufactured by Lockheed Martin. The services of the original design are voice, data, fax and paging throughout Southeast Asia, China and India. In this paper, we present a supplementary design, which called ACeS Multi-media System (AMS), for the original ACeS to offer some more narrow-band multi-media services such as Internet, Intranet and ISDN services to mobile or fixed users thus to make it more competitive in the market. The paper discusses the system description, frame/burst formats of satellite transmission links, design of the combining scheme of turbo codes and QAM modulation etc. This system can also be modified for military communications.
A Comparison of Functional and Structural Consequences of the Tyrosine B10 and Glutamine E7 Motifs in Two Invertebrate Hemoglobins (<i>Ascaris</i> <i>suum</i> and <i>Lucina</i> <i>pectinata</i>) (1997)

The architecture of the distal heme pocket in hemoglobins and myoglobins can play an important role in controlling ligand binding dynamics. The size and polarity of the residues occupying the distal pocket may contribute steric and dielectric effects. In vertebrate systems, the distal pocket typically contains a "distal" histidine at position E7 and a leucine at position B10. There are several invertebrate organisms that have hemoglobins or myoglobins that display a pattern in which residues E7 and B10 are a glutamine and tyrosine, respectively. These proteins often have very high oxygen affinities stemming from very slow ligand off rates. In this study, two such hemoglobins, one from the nematode Ascaris suum and the other from the sulfide-fixing clam Lucina pectinata, are compared with respect to conformational and functional properties. Ultraviolet resonance Raman spectroscopy and visible resonance Raman spectroscopy are used to probe, respectively, the ligand-dependent hydrogen bonding pattern of the tyrosine residues and the proximal heme pocket interactions. Fourier transform infrared absorption spectroscopy is used to probe the dielectric properties of the distal heme pocket through the stretching frequency of carbon monoxide bound to the heme. Functionality is probed through the geminate rebinding of both CO and O2. The findings reveal two very different patterns indicative of two different mechanisms for achieving low oxygen off rates. In Hb Ascaris, a hydrogen bonding network that includes the E7 Gln, B10 Tyr, and oxygen bound to the heme results in a tight cage for the oxygen. Dissociation of the O2 requires a large amplitude conformational fluctuation that results both in a spontaneous dissociation of the oxygen through the loss of hydrogen bond stabilization and in an enhanced probability for ligand escape though the transient disruption and opening of the tight distal cage. In the case of the Hb from Lucina, there is no evidence for a tight cage. Instead the data support a model in which the hydrogen bonding network is far more tenuous and the equilibrium state of distal pocket is far more open and accessible than is the case in Ascaris. The results explain why Hb Ascaris has one of the highest oxygen affinities known (P50 approximately 10(-)3 Torr) while Hb Lucina II has an oxygen affinity comparable to that of Mb (P50 = 0.13 Torr) even though both of these Hbs contain the B10 Tyr and E7 Gln motif and display very low oxygen off rates. The roles of water and proximal strain are discussed.
Down-regulation of retinoic acid receptor beta in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells. (1994)

Retinoids are important cellular, dietary factors that regulate differentiation and cellular growth. They serve as ligands for specific nuclear receptors, the retinoic acid receptors (RARs). Ligand-activated receptors regulate gene transcription through target retinoic acid-responsive elements (RAREs) found in promoter regions. We have investigated the expression of retinoic acid receptor genes (alpha, beta, gamma) and retinoid X receptor beta in normal, senescing, and tumorigenic human mammary epithelial cells. We find that most tumor cells show a loss of RAR-beta expression, but that RAR-alpha and -gamma as well as retinoid X receptor beta are variably expressed in both normal and tumor cells. RAR-beta gene expression is induced both by retinoic acid and by fenretinide in normal cells, but tumor cells fail to respond to either. In contrast, RAR-beta expression increases with serial passage in senescing cells. Paradoxically, both normal and tumor cells can trans-activate an exogenous beta-RARE, as demonstrated by reporter gene assays. Oligonucleotide mobility shift assays with the beta-RARE show a single discrete complex in normal cells, whereas tumor cells exhibit a heterogeneous set of larger complexes, which indicates that tumor cells utilize a different array of factors within the beta-RARE. Reporter gene assays with extended promoter regions indicate the presence of negative regulatory elements and/or factor binding sites that reside between -1500 and the RARE located at -59, and that the promoter is down-regulated in MCF-7 tumor cells. Our findings reveal a dichotomy: RAR-beta transcription is down-regulated in tumor cells compared with normal human mammary epithelial cells, and up-regulated in senescence.
High-Efficiency Ferroelectric-Film Solar Cells with an n-type Cu<sub>2</sub>O Cathode Buffer Layer (2012)

Because of the existence of interface Schottky barriers and depolarization electric field, ferroelectric films sandwiched between top and bottom electrodes are strongly expected to be used as a new kind of solar cells. However, the photocurrent with a typical order of μA/cm(2) is too low to be practical. Here we demonstrate that the insertion of an n-type cuprous oxide (Cu(2)O) layer between the Pb(Zr,Ti)O(3) (PZT) film and the cathode Pt contact in a ITO/PZT/Pt cell leads to the short-circuit photocurrent increasing 120-fold to 4.80 mA/cm(2) and power conversion efficiency increasing of 72-fold to 0.57% under AM1.5G (100 mW/cm(2)) illumination. Ultraviolet photoemission spectroscopy and dark J-V characteristic show an ohmic contact on Pt/Cu(2)O, an n(+)-n heterojunction on Cu(2)O/PZT and a Schottky barrier on PZT/ITO, which provide a favorable energy level alignment for efficient electron-extraction on the cathode. Our work opens up a promising new method that has the potential for fulfilling cost-effective ferroelectric-film photovoltaic.
Preference iof the recombination sites involved in the formation of extrachromosomal copies of the human alphoid Sau3A repat family (1995)

The human alphoid Sau3A repetitive family DNA is one of the DNA species that are actively amplified to form extrachromosomal circular DNA in several cell lines. The circularization takes place between two of the five approximately 170 bp subunits with an average of 73.1% homology as well as between identical subunits. To investigate the nature of the recombination reaction, we cloned and analyzed the subunits containing recombination junctions. Analysis of a total of 68 junctions revealed that recombination had occurred preferentially at four positions 10-25 (A), 40-50 (B), 85-90 (C) and 135-160 (D) in the 170bp subunit structure. Two regions (B and C) were overlapped with the regions with higher homology between subunits, while other two regions (A and D) cannot be explained solely by the regional homology between the subunits. These regions were located at both junctions of the nucleosomal and the linker region, and overlapped with the binding motifs for alpha protein and CENP-B. Approximately 90% of the recombination occurred between the subunits located next but one (+/- 2 shift), although the frequency of recombination between the adjoining subunits (+/- 1 shift) was approximately 10%.
A High-Speed, High-Sensitivity Digital CMOS Image Sensor With a Global Shutter and 12-bit Column-Parallel Cyclic A/D Converters (2007)

This paper presents a high-speed, high-sensitivity 512times512 CMOS image sensor with column parallel cyclic 12-bit ADCs and a global electronic shutter. Each pixel has a charge amplifier for high charge-to-voltage conversion gain despite of using a large-size photodiode, and two sample-and-hold stages for the global shutter and fixed pattern noise (FPN) canceling. High-speed column-parallel cyclic ADC arrays with 12-bit resolution having a small layout size of 0.09 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> are integrated at both sides of image array. A technique for accelerating the conversion speed using variable clocking and sampling capacitance is developed. A digital gain control function using 14-bit temporal digital code is also set in the column parallel ADC. The fabricated chip in 0.25-mum CMOS image sensor technology achieves the full frame rate in excess of 3500 frames/s. The in-pixel charge amplifier achieves the optical sensitivity of 19.9 V/lxmiddots. The signal full scale at the pixel output is 1.8 V at 3.3-V supply and the noise level is measured to be 1.8mV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rms</sub> , and the resulting signal dynamic range is 60 dB
Triclosan and antibiotic resistance in Staphylococcus aureus (2000)

Triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether) is an antimicrobial agent used in hygiene products, plastics and kitchenware, and for treating methicillin-resistant Staphylococcus aureus (MRSA) outbreaks. S. aureus strains with low-level resistance to triclosan have emerged. It has been claimed that strains with decreased susceptibility to biocides may also be less susceptible to antibiotics. We tested the susceptibility of S. aureus clinical isolates to triclosan and several antibiotics. Triclosan MICs ranged between 0.025 and 1 mg/L. Some, but not all, strains were resistant to several antibiotics and showed low-level triclosan resistance. S. aureus mutants with enhanced resistance to triclosan (< or =1 mg/L) were isolated. In several cases this resistance was stably inherited in the absence of triclosan. These mutants were not more resistant than the parent strain to several antibiotics. Changes in triclosan MICs associated with the acquisition of a plasmid encoding mupirocin resistance were not observed, suggesting that the triclosan/mupirocin co-resistance seen in a previous study was not the result of a single resistance gene or separate genes on the same plasmid. The continuous exposure of a triclosan-sensitive S. aureus strain to sub-MIC concentrations of triclosan for 1 month did not result in decreased susceptibility to triclosan or to several antibiotics tested. Triclosan-induced potassium leakage and bactericidal effects on a triclosan-sensitive strain, a resistant strain and a strain selected for increased resistance were compared with those of non-growing organisms, exponentially growing organisms and organisms in the stationary phase. No significant differences between the strains were observed under these conditions despite their different MICs. Biocides have multiple target sites and so MICs often do not correlate with bactericidal activities. The ability of S. aureus to develop resistance to triclosan and the current view that triclosan may have a specific target in Escherichia coli, namely enoyl reductase, underline the need for more research on the mechanisms of action and resistance.
Site-directed psoralen crosslinking of DNA. (1982)

A technique has been developed for placing site-specific crosslinks into DNA by using a psoralen derivative containing a sulfhydryl group. Plasmid pBR322 was nicked at the unique BamHI restriction site, and mercurated pyrimidines were introduced by nick-translation. Then the psoralen was specifically directed to this site in the dark through a Hg-S linkage prior to irradiation to form a crosslink. The location of interstrand cross-links was examined by electron microscopy of Pst I-cut molecules and found to be at or near the BamHI site.