gebhart/patrepeval huggingface dataset:
A New Compact Microstrip-Fed Dual-Band Coplanar Antenna for WLAN Applications (2006)

A novel compact microstrip fed dual-band coplanar antenna for wireless local area network is presented. The antenna comprises of a rectangular center strip and two lateral strips printed on a dielectric substrate and excited using a 50 Omega microstrip transmission line. The antenna generates two separate resonant modes to cover 2.4/5.2/5.8 GHz WLAN bands. Lower resonant mode of the antenna has an impedance bandwidth (2:1 VSWR) of 330 MHz (2190-2520 MHz), which easily covers the required bandwidth of the 2.4 GHz WLAN, and the upper resonant mode has a bandwidth of 1.23 GHz (4849-6070 MHz), covering 5.2/5.8 GHz WLAN bands. The proposed antenna occupy an area of 217 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> when printed on FR4 substrate (epsiv <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> =4.7). A rigorous experimental study has been conducted to confirm the characteristics of the antenna. Design equations for the proposed antenna are also developed
Visual C# 2005: How to Program (2005)

Created by world-renowned programming instructors Paul and Harvey Deitel, Visual C# 2008 How to Program, Third Edition introduces all facets of the C# 2008 language through the Deitels' signature Live Code Approach, that features hundreds of working programs. This book has been thoroughly updated to reflect the major innovations Microsoft has incorporated in Visual C# 2008 and .NET 3.5; The many new platform features covered include: LINQ (Language Integrated Query), Windows Presentation Foundation (WPF), ASP.NET Ajax and the Microsoft Ajax Library, Silverlight-based rich Internet application development, and creating Web services with Windows Communication Foundation (WCF). New language features introduced in this edition: automatic properties, object initializers, partial classes and methods, anonymous methods, Lambda expressions, extension methods, anonymous types, and collection initializers. Extensively updated coverage of delegates.and more sophisticated techniques, including searching, sorting, data structures, generics, and collections. Appendices provide essential programming reference material on topics ranging from number systems to the Visual Studio Debugger, UML 2 to Unicode and ASCII. Appropriate for all basic-to-intermediate level Visual C# 2008 programmers.
Colonic mucus: secretion and turnover in relation to dietary fibre intake (2003)

The colon is subjected to a myriad of potentially damaging agents that may reside within the lumen for 1-2 d. Its first line of defence against these agents is the protective mucus bilayer that lines the entire colonic mucosa. This bilayer acts as a physical barrier to mucosal aggressors and also reduces shear stress to the mucosa. These actions are dependent on the unstimulated ('resting') colonic mucus thickness, and also on the rate that this layer can be replenished. The colonic mucus layer is altered in a number of colonic diseases that have been linked to a deficiency of fibre in the diet. The action of fibre intake on colonic mucus thickness and secretion is unknown. Using an in vivo rat model it has been demonstrated that: (1). fibre deficiency leads to a decreased protective potential of the mucus layer (e.g. the mean resting mucus thickness of the fibre-deficient group (429 microm) was significantly lower than its respective control (579 microm; P< 0-001), as was its total mucus secretion over 6 h (270 microm v. 541 microm; P<0-01); (2). specific fibre types in the diet alter the secretion dynamics of colonic mucus (e.g. a cellulose-based diet reduces total mucus secretion over 6 h compared with its control (175 microm v. 463 microm). Analysis of the diets suggested a necessity for both soluble and insoluble fibre types in the diet to increase mucosal protection.
Computer-Based Ligand Design and Synthesis of Some New Sulfonamides Bearing Pyrrole or Pyrrolopyrimidine Moieties Having Potential Antitumor and Radioprotective Activities (2007)

A series of new Pyrrole and pyrrolo[2,3-d]pyrimidine derivatives ( 5–15 ) was designed, synthesized, and biologically evaluated for their in vitro cytotoxic activity. The design of these compounds was based upon the molecular modeling simulation of the fitting values and conformational energy values of the best-fitted conformers to VEGFRTK inhibitors hypothesis. This hypothesis was generated from its corresponding lead compounds using CATALYST software. Some of the newly synthesized compounds 8 , 11 , 12 , and 13 showed interesting cytotoxic activity compared with Doxorubicin as a reference drug. These results are nearly consistent with the molecular modeling studies. Moreover, Compound 7 showed significant radioprotective activity.
Metal−Organic Frameworks Provide Large Negative Thermal Expansion Behavior (2007)

Using molecular dynamics (MD) simulations, we show that metal−organic frameworks (MOFs) constructed using octahedral Zn4O(CO2)6 clusters linked via aromatic carbon ring structures lead to negative thermal expansion (NTE) behavior (from 0 K to melting). We find that MOF-C22 contracts volumetrically by 1.9% over the range of 0 to 600 K, making it one of the best NTE materials (linear expansion coefficient of α = −11.05 × 10-6 K-1 compared with α = −9.1 × 10-6 K-1 found for ZrW2O8, previously the champion NTE material). Indeed, we designed a new MOF using 2-butynediodate linkers that leads to an even larger NTE of 2.2% (from 0 to 500 K). We show that this NTE behavior arises because thermal motions in the rigid Zn−O clusters and the organic moieties linking them lead to tilting of the linkers by successively larger amounts from their alignment along the unit cell axes, resulting in decreased cell parameters. The MOF materials were developed to provide a large reversible hydrogen-storage capacity leading to as much as 73% free volume. However, the NTE properties suggest other possible applications. Thus, their porous but constrained three-dimensional framework provides a framework onto which other materials might blend to form composites with negligible volume change with temperature. To illustrate this, we incorporated polyethylene polymers into MOF-C10 and found that the volume of the composite is constant within 0.059% over the entire range from 300 to 600 K.
Emission linewidth measurements of two-dimensional array Josephson oscillators (1994)

We have coupled emission from 10×10 arrays of Josephson junctions at 4 K to a room-temperature mixer through a fin-line antenna and a WR-12 waveguide. A single voltage-tunable peak was detected in the frequency range from 53 to 230 GHz. A stripline resonance in the antenna reduced the array’s dynamic resistance and thereby the emission linewidth to as low as 10 kHz. We extract an effective noise temperature of 14 K from the linewidth data.
Perturbation analysis of fluxon dynamics (1978)

A two-stage scheme is presented to study structural perturbations of the sine-Gordon equation. Although the method is based upon the inverse scattering transform, detailed knowledge of this technical apparatus is not necessary in order to effect the calculations. In the first stage, slow modulations of speeds and positions for the soliton components are computed. The radiation resulting from the acceleration of the solitons is then calculated as a first-order correction through an easily constructed radiative Green's function. The method is exemplified by using it to study several outstanding problems that arise in applications of the Josephson transmission line. In particular we consider: (i) the pinning of flux quanta by microshorts, (ii) the quantum flux shuttle, (iii) annihilation conditions for fluxon-antifluxon collisions, (iv) breather decay, and (v) radiation from a moving fluxon.
A Post-Operative Regime after Digital Flexor Tenolysis (1993)

Tenolysis of the flexor tendons was performed in 78 fingers (72 patients) by the same surgeon. Two technical modifications were introduced: reconstruction of a robust pulley; and initial immobilization with the tendon in a proximally migrated position, permitting later breakdown of early adhesions by gentle extension either by the surgeon or using an extension spring. After a mean follow-up of 21.5 months, the total active movement was improved from 135 degrees (pre-operative) to 203 degrees (post-operative) in 84% of fingers and from 65 degrees to 115 degrees in 78% of thumbs. This corresponds to a reduction in impairment of 10.1% for the thumb and 21.6% for the fingers. There was no improvement in four digits and nine cases were made worse, averaging a loss of range of 25.4 degrees. Among these were two cases of skin breakdown and two cases of tendon rupture (2.5%), one combined with skin necrosis.
Diagnosis of Chlamydia pneumoniae Infection in Patients with Community-Acquired Pneumonia by Polymerase Chain Reaction Enzyme Immunoassay (1994)

We conducted a prospective study of 385 patients who had community-acquired pneumonia with use of a modified polymerase chain reaction (PCR) assay that detects amplified DNA by enzyme immunoassay (EIA). We used PCR-EIA to improve detection of Chlamydia pneumoniae infection and to differentiate C. pneumoniae infection from other chlamydial infections. Cultures of throat swab specimens from four patients yielded Chlamydia species (C. pneumoniae, one patient; Chlamydia species, two patients; and C. psittaci, one patient). C. pneumoniae was repeatedly detected by PCR-EIA for thirteen (3.4%) of these 385 patients. Six of these 13 patients were infected with the human immunodeficiency virus. Ten (76.9%) of the patients who were positive by PCR-EIA had IgG titers of > or = 1:16, and two (15.4%) of the 13 patients had IgG titers of < 1:16; no sera was available in one case. Other pathogens were recovered in eight (61.5%) of the 13 cases in which C. pneumoniae was detected by PCR-EIA. In addition, for 46 (11.9%) of the 385 patients the titers of antibody were considered diagnostic of C. pneumoniae infection; however, as 36 of the 46 patients were infected with the human immunodeficiency virus (which may have affected their serological response to C. pneumoniae), interpretation of these titers was problematic. As PCR-EIA was more sensitive than was culture for detecting C. pneumoniae infection in this study, this method may be a valuable tool for the prompt diagnosis of this infection.
Transmission Dynamics of the Etiological Agent of SARS in Hong Kong: Impact of Public Health Interventions (2003)

We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing community transmission. By fitting a stochastic model to data on 1512 cases, including these clusters, we show that the etiological agent of SARS is moderately transmissible. Excluding SSEs, we estimate that 2.7 secondary infections were generated per case on average at the start of the epidemic, with a substantial contribution from hospital transmission. Transmission rates fell during the epidemic, primarily as a result of reductions in population contact rates and improved hospital infection control, but also because of more rapid hospital attendance by symptomatic individuals. As a result, the epidemic is now in decline, although continued vigilance is necessary for this to be maintained. Restrictions on longer range population movement are shown to be a potentially useful additional control measure in some contexts. We estimate that most currently infected persons are now hospitalized, which highlights the importance of control of nosocomial transmission.
Prognostic Significance of Preoperative [18-F] Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) Imaging in Patients With Resectable Soft Tissue Sarcomas (2005)

The semiquantitative FDG uptake, as measured by the mean SUV on preoperative PET images in patients with resectable STS, is a useful prognostic parameter. SUV with cutoff values at the first and the third quartiles of the SUV distribution predicted overall survival, recurrence-free survival, and local tumor control. Therefore, FDG-PET can be used to improve the preoperative prognostic assessment in patients with resectable STS.
Multielement atomic absorption with a continuum source (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleMultielement atomic absorption with a continuum sourceJames M. HarnlyCite this: Anal. Chem. 1986, 58, 8, 933A–943APublication Date (Print):July 1, 1986Publication History Published online22 September 2008Published inissue 1 July 1986https://pubs.acs.org/doi/10.1021/ac00121a003https://doi.org/10.1021/ac00121a003research-articleACS PublicationsRequest reuse permissionsArticle Views273Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis, transformations and tuberculostatic activity of 1-(N-aroylthiocarbamoyl)imidiazolidine-2-thiones. (1993)

Series of 1(N-aroylthiocarbamoyl)imidiazolidine-2-thiones and 3-aroylimino-5,6-dihydro-3H-imidazo[2,1-c](1,2,4) dithiazoles were prepared for antituberculostatic screening. Dithiobiuret was transformed into N1-disubstituted thiocarbamoyl 1-N-aroylthiocarbamoyl ethylenediamines by reacting with secondary amines or hydrazine derivatives.
Fall risk assessment: A prospective investigation of nurses’ clinical judgement and risk assessment tools in predicting patient falls (2003)

A prospective cohort study was used to determine the reliability and validity of two fall risk assessment tools and nurses' clinical judgement in predicting patient falls. The study wards comprised two aged care and rehabilitation wards within a 570 bed acute care tertiary teaching hospital in Western Australia. Instrument testing included test-retest reliability and calculations of sensitivity, specificity, positive predictive value, negative predictive value and accuracy. The test retest reliability of all methods was good. In this setting, the three methods of assessing fall risk showed good sensitivity but poor specificity. Also, all methods had limited accuracy, and overall, exhibited an inability to adequately discriminate between patient populations at risk of falling and those not at risk of falling. Consequently, neither nurses' clinical judgement nor the fall risk assessment tools could be recommended for assessing fall risk in this clinical setting.
Femtosecond time-resolved photoemission study of hot electron relaxation at the GaAs(100) surface (1996)

Time-resolved two-photon photoemission spectroscopy is used to study the relaxation of hot electrons as a function of excitation energy for a variety of device grade and molecular beam epitaxial grown GaAs(100) surfaces. Relaxation times ranging from tens of femtoseconds to greater than 400 fs are observed depending on the energy of the intermediate state, the surface quality, and the bulk material quality. This study provides detailed information on electron relaxation dynamics in the corresponding energy range and spatial distribution along the surface normal relevant to hot electron transfer processes at interfaces.
Abstract 3829: Inhibition of breast cancer metastasis by deguelin in an experimental model (2012)

Abstract Breast cancer is a second leading cause of cancer related deaths in women. Cancer related deaths in breast cancer patients are due to metastasis of disease. Thus new drugs which could successfully inhibit metastatic disease spread are highly desired. However till date there are only a few experimental models available to study metastatic progression of breast cancer. Murine 4T1 mammary breast cancer cells when transplanted s.c./or into mammary gland metastasizes to lungs, liver and bone similar to that observed in women with stage IV metastatic disease. Thus this model is highly appropriate for studies related to breast cancer metastasis. Previously we have shown that Deguelin, originally isolated from an African plant Mundulea sericea significantly inhibits the growth of triple negative breast cancer and that the Deguelin effect is mediated through inhibition of WNT signaling pathway. However their therapeutic effect in vivo is still unexplored. We evaluated the effects of Deguelin on growth (in vitro and in vivo) and lung metastasis of 4T1 cells. In vitro, Deguelin inhibited growth of 4T1 cells in time and concentration depended manner; optimum growth inhibition was obtained at 250nM Deguelin concentration after 72 hr. treatment. Toxicity study performed in 4-6 weeks old female BALB/c mice suggested that Deguelin administered as a suspension (saline/gum Arabic/Deguelin) daily for two weeks by intraperitoneal (i.p.) injection was well tolerated up to 16mg/kg body weight, and no toxicity (loss of appetite, body weight loss, mobility, morbidity, death) was observed in Deguelin treated animals. In vivo, as compared to vehicle treated animals, Deguelin (2 or 6mg/kg body weight) administered daily for 21 days i.p significantly (P&lt;0.05) inhibited growth of 4T1 cells (0.5 million cells/mouse) transplanted s.c. in to 4-6 weeks old female BALB/c mice. Similarly Deguelin also reduced (27-33%, P&lt; 0.02) the number of metastatic lesions in the lungs subsequent to i.v. injection of 7500 to 10,000 4T1 cells in syngeneic mice as compared to vehicle treated control group. Immunohistochemical analysis of control/Deguelin treated 4T1 cells, and lung metastatic lesions suggest that Deguelin inhibited Ki67 expression suggesting its antiproliferative action in this model. In addition, phospho AKT, cyclin D1, Cox-2 and Hif-1α protein expressions were down regulated. Our results suggest that Deguelin effect on the growth and metastasis may be mediated by targeting signaling molecules involved in pAKT, HIF-1, Cox-2 pathway. These results provide a promising lead for a potential therapeutic agent to treat metastatic breast cancer. This work was supported in part by the National Cancer Institute grant CA140321. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 3829. doi:1538-7445.AM2012-3829
Using a formal specification and a model checker to monitor and direct simulation (2003)

We describe a technique for verifying that a hardware design correctly implements a protocol-level formal specification. Simulation steps are translated to protocol state transitions using a refinement map and then verified against the specification using a model checker. On the specification state space, the model checker collects coverage information and identifies states violating certain properties. It then generates protocol-level traces to these coverage gaps and error states. This technique was applied to the multiprocessing hardware of the Alpha 21364 microprocessor and the cache coherence protocol. We were able to generate an error trace which exercised a bug in the implementation that had not been discovered before a prototype was built.
Blockade of TGF‐β enhances tumor vaccine efficacy mediated by CD8<sup>+</sup> T cells (2009)

Though TGF-beta inhibition enhances antitumor immunity mediated by CD8(+) T cells in several tumor models, it is not always sufficient for rejection of tumors. In this study, to maximize the antitumor effect of TGF-beta blockade, we tested the effect of anti-TGF-beta combined with an irradiated tumor vaccine in a subcutaneous CT26 colon carcinoma tumor model. The irradiated tumor cell vaccine alone in prophylactic setting significantly delayed tumor growth, whereas anti-TGF-beta antibodies alone did not show any antitumor effect. However, tumor growth was inhibited significantly more in vaccinated mice treated with anti-TGF-beta antibodies compared to vaccinated mice without anti-TGF-beta, suggesting that anti-TGF-beta synergistically enhanced irradiated tumor vaccine efficacy. CD8(+) T-cell depletion completely abrogated the vaccine efficacy, and so protection required CD8(+) T cells. Depletion of CD25(+) T regulatory cells led to the almost complete rejection of tumors without the vaccine, whereas anti-TGF-beta did not change the number of CD25(+) T regulatory cells in unvaccinated and vaccinated mice. Though the abrogation of CD1d-restricted NKT cells, which have been reported to induce TGF-beta production by MDSC through an IL-13-IL-4R-STAT6 pathway, partially enhanced antitumor immunity regardless of vaccination, abrogation of the NKT cell-IL-13-IL-4R-STAT-6 immunoregulatory pathway did not enhance vaccine efficacy. Taken together, these data indicated that anti-TGF-beta enhances efficacy of a prophylactic vaccine in normal individuals despite their not having the elevated TGF-beta levels found in patients with cancer and that the effect is not dependent on TGF-beta solely from CD4(+)CD25(+) T regulatory cells or the NKT cell-IL-13-IL-4R-STAT-6 immunoregulatory pathway.
Catalytic Reduction of CO<sub>2</sub> to CO by Using Zinc(II) and In Situ Generated Carbodiphosphoranes (2013)

Playing it 'CO'ol: CO(2) is catalytically reduced to CO with concurrent oxidation of phosphine to phosphineoxide by using an in situ generated catalyst derived from a carbodiphosphorane and zinc(II).
Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity (2014)

Ruthenium compounds have become promising alternatives to platinum drugs by displaying specific activities against different cancers and favourable toxicity and clearance properties. Nonetheless, their molecular targeting and mechanism of action are poorly understood. Here we study two prototypical ruthenium-arene agents-the cytotoxic antiprimary tumour compound [(η(6)-p-cymene)Ru(ethylene-diamine)Cl]PF6 and the relatively non-cytotoxic antimetastasis compound [(η(6)-p-cymene)Ru(1,3,5-triaza-7-phosphaadamantane)Cl2]-and discover that the former targets the DNA of chromatin, while the latter preferentially forms adducts on the histone proteins. Using a novel 'atom-to-cell' approach, we establish the basis for the surprisingly site-selective adduct formation behaviour and distinct cellular impact of these two chemically similar anticancer agents, which suggests that the cytotoxic effects arise largely from DNA lesions, whereas the protein adducts may be linked to the other therapeutic activities. Our study shows promise for developing new ruthenium drugs, via ligand-based modulation of DNA versus protein binding and thus cytotoxic potential, to target distinguishing epigenetic features of cancer cells.
Diagnosis and treatment control of bleeding intestinal angiodysplasias with an endoscopic Doppler device. (1995)

Endoscopic Doppler ultrasonography may help in identification and treatment of intestinal angiodysplasias. The technically simple method allows objective evaluation of the endoscopic findings and enables monitoring of local endoscopic therapy.