gebhart/patrepeval huggingface dataset:
A Fundamental Study on In-Situ Method for Removal of Nitrate-Nitrogen Contaminated Groundwater (2006)

One of worsening environmental problems is contamination of groundwater by nitrate-nitrogen supplied by excessive amounts of agricultural fertilizer. In order to remove such nitrate-nitrogen at a site, installation of a permeable reactor barrier (PRB) is thought to be a solution. A sulfur/limestone autotrophic denitrification (SLAD) system is known to be closer to a natural system of removing nitrate from groundwater. In this research, application of this SLAD system to the PRB was examined. Feasibility of the SLAD system was evaluated from a series of experiments using three column reactors. Consequently, nitrate- and nitrite-nitrogen first-order reaction rate constants were obtained from the column experiments and the nitrate- and nitrite-nitrogen profiles were clarified based on the first-order reaction rate. By calculating the designed thickness of the PRB, the application of the SLAD system to the PRB was confirmed to be feasible.
Port Buffers: A Mach IPC Optimization for Handling Large Volumes of Small Messages (1993)

The two surgical procedures are reliable in terms of safety and efficacy, and each has distinct advantages. While OAGB has reduced operational expenses, SADJB-SG offers a broader range of applicability.
An intelligent sensor network system coupled with statistical process model for predicting machinery health and failure (2003)

Application of statistical process for the purpose of health monitoring of machinery and system is the main purpose of this paper. The system has two main parts. The first, sensing and transmitting of variable by a network of intelligent sensors and transducers. The second, analysis and prognosis of machinery health by a two-step statistical process model (SPM). Most contemporary intelligent sensors have signal-conditioning circuit integrated within the sensor as a single chip device. In many instances sensor and signal conditioning circuit are packaged together as one unit. However, intelligent sensors are becoming increasingly important for many critical applications. An intelligent sensor network system can perform sensing and transmitting of variables for the process controller and can also locally store and transmit sensed variable over wireless link to remote central processing computer. The central processing computer is used for continuous statistical analysis of multiple variables and can be used for predicting machinery failure. Operators at remote location can review processed information at any instant of time and determine imminent and prospective condition of the machinery. Currently we are researching to develop an intelligent sensor network system that will sense and temporarily store process variables and periodically transmit them to a remote location for processing, analyzing, and storing. The process variables are transmitted to the central computer as well as to the controller for continuous control of the process. The statistical process model (SPM) located in the central computer system will analyze the related data for predicting machinery failure and prognostic maintenance.
D-4-AMINO-3-ISOXAZOLIDONE, A NEW ANTIBIOTIC<sup>*</sup> (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTD-4-AMINO-3-ISOXAZOLIDONE, A NEW ANTIBIOTIC*Frederick A. Kuehl Jr., Frank J. Wolf, Nelson R. Trenner, Robert L. Peck, Rudolf P. Buhs, Eugene Howe, Irvin Putter, Berl D. Hunnewell, Robert Ormond, George Downing, John E. Lyons, E. Newstead, Louis Chaiet, and Karl FolkersCite this: J. Am. Chem. Soc. 1955, 77, 8, 2344–2345Publication Date (Print):April 1, 1955Publication History Published online1 May 2002Published inissue 1 April 1955https://pubs.acs.org/doi/10.1021/ja01613a105https://doi.org/10.1021/ja01613a105research-articleACS PublicationsRequest reuse permissionsArticle Views271Altmetric-Citations64LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Antisense c- <i>myc</i> Retroviral Vector Suppresses Established Human Prostate Cancer (1998)

Prostate cancer eventually becomes androgen resistant, resumes growth, and kills the patient. Characterization of genetic events that lead to androgen refractory prostatic neoplasia has revealed the frequent overexpression of c-myc and uncontrolled prostate cancer proliferation. A novel strategy to combat advanced prostate cancer utilized a replication incompetent retrovirus that contained the mouse mammary tumor virus (MMTV) promoter within the retroviral vector to allow transcription of antisense c-myc gene within target prostate tumor cells. The transduction of cultured DU145 cells by XM6:MMTV-antisense c-myc RNA retrovirus did not affect cell proliferation in culture, yet a single direct injection of MMTV-antisense c-myc viral media into established DU145 tumors in nude mice produced a 94.5% reduction in tumor size compared to tumors treated with control virus MTMV sense fos and untreated tumor by 70 days. Two animals in the antisense c-myc-treated group had complete regression of their tumors. Histopathological examination of the tumors revealed that MMTV-antisense c-myc-transduced DU145 tumors had increased tumor cell differentiation, decreased invasion, and a marked stromal response. The mechanism for the antitumor effect of MMTV-antisense c-myc retrovirus appears to be suppression of c-myc mRNA and protein, and decreased bcl-2 protein. The in vivo transduction of prostate cancer cells with MMTV-antisense c-myc retroviruses reduced tumor growth by suppressing c-myc, resulting in the down-regulation of bcl-2 protein. Consequently, the MMTV-antisense c-myc retrovirus may be useful for gene therapy against advanced, hormone-refractory prostate cancer.
A motion control of two-wheels driven mobile manipulator for human-robot cooperative transportation (2009)

This paper proposes a control method for humanrobot cooperative transportation using two-wheels driven mobile manipulator. In the past, most of the robots which aim at cooperation with human had three or more wheels, and there is a possibility that their mobility is insufficient for human environment. Two-wheels driven mobile manipulator has excellent mobility and can realize rapid and smooth motion such as turning instantly. It has different motion characteristics depending on the configuration, because of the nonholonomic constraint of the mobile platform. And, there is a trade-off between the robot's mobility and the robot's stability. In this paper, to the above mentioned problem, we propose a method of configuration control of the mobile platform by setting the manipulability measure as a performance index. In the proposed method, by maximizing or minimizing the performance index depending on the situation, mobility and stability of the mobile platform in the cooperative transportation is controlled.
Antinuclear Antibodies in Patients with Atopic Dermatitis and Severe Facial Lesions (1994)

Adult AD patients with severe facial lesions should be examined for serum ANA. Particularly in female and photosensitive AD patients with severe facial lesions, serum autoantibodies have to be carefully investigated to differentiate from autoimmune diseases.
An Essay in Modal Logic. (1953)

Book Reviews Get access An Essay in Modal Logic. By Georg H. von Wright. (Studies in Logic and the Foundations of Mathematics. Amsterdam: North-Holland Publishing Company. 1951. Pp. viii + 90. Price Fl.9). G. P. Henderson G. P. Henderson Search for other works by this author on: Oxford Academic Google Scholar The Philosophical Quarterly, Volume 3, Issue 12, July 1953, Page 287, https://doi.org/10.2307/2216596 Published: 01 July 1953
Synthesis and Characterization of 4-Iodophenylboronic Acid: A New Enhancer for the Horseradish Peroxidase-Catalyzed Chemiluminescent Oxidation of Luminol (1996)

4-Iodophenylboronic acid has been synthesized and shown to be a potent enhancer of the chemiluminescent horseradish peroxidase (Type VI-A)-catalyzed oxidation of luminol and isoluminol. The enhancer was effective (>100-fold enhancement) in the concentration range 10-1500 microM. Light emission in the presence of the enhancer peaked at 5-10 min after initiation of the reaction and then decayed very slowly. 4-Iodophenylboronic acid also enhanced reactions catalyzed by horseradish peroxidase Type IX. The detection limit for Type VI-A horseradish peroxidase was 509 amol, and optimum signal enhancement was obtained at 769 microM compared to 154 microM for 4-iodophenol under the same conditions.
miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy (2015)

Small RNA RNA-seq for microRNAs (miRNAs) is a rapidly developing field where opportunities still exist to create better bioinformatics tools to process these large datasets and generate new, useful analyses. We built miRge to be a fast, smart small RNA-seq solution to process samples in a highly multiplexed fashion. miRge employs a Bayesian alignment approach, whereby reads are sequentially aligned against customized mature miRNA, hairpin miRNA, noncoding RNA and mRNA sequence libraries. miRNAs are summarized at the level of raw reads in addition to reads per million (RPM). Reads for all other RNA species (tRNA, rRNA, snoRNA, mRNA) are provided, which is useful for identifying potential contaminants and optimizing small RNA purification strategies. miRge was designed to optimally identify miRNA isomiRs and employs an entropy based statistical measurement to identify differential production of isomiRs. This allowed us to identify decreasing entropy in isomiRs as stem cells mature into retinal pigment epithelial cells. Conversely, we show that pancreatic tumor miRNAs have similar entropy to matched normal pancreatic tissues. In a head-to-head comparison with other miRNA analysis tools (miRExpress 2.0, sRNAbench, omiRAs, miRDeep2, Chimira, UEA small RNA Workbench), miRge was faster (4 to 32-fold) and was among the top-two methods in maximally aligning miRNAs reads per sample. Moreover, miRge has no inherent limits to its multiplexing. miRge was capable of simultaneously analyzing 100 small RNA-Seq samples in 52 minutes, providing an integrated analysis of miRNA expression across all samples. As miRge was designed for analysis of single as well as multiple samples, miRge is an ideal tool for high and low-throughput users. miRge is freely available at http://atlas.pathology.jhu.edu/baras/miRge.html.
Four-Year Calibration Stability of the EasyOne Portable Spirometer (2010)

The EasyOne retained inhalation and exhalation volume accuracy of better than 3% for at least 4 years. Routine multiple-speed volume calibration checks may not be necessary with the EasyOne. The acceptability and repeatability of patient efforts should be the primary focus of quality-assurance programs with spirometers that have been demonstrated to remain accurate for long periods.
The autonomy of the rabbit corpus luteum (1994)

The rabbit corpus luteum possesses LH receptors that are coupled to adenylyl cyclase, but paradoxically it does not require LH as a luteotrophic factor for the maintenance of progesterone secretion. This suggests that rabbit luteal cells may not respond physiologically to LH. Therefore, the present study was undertaken to investigate the responsiveness of the rabbit corpus luteum of pseudopregnancy to human chorionic gonadotrophin (hCG) which acts on the same receptor as LH. Pseudopregnancy was induced by injection of 40 IU pregnant mare serum gonadotrophin followed 50 h later by an injection of 40 IU hCG (day 0). On days 7 and 11 of pseudopregnancy, corpora lutea were obtained and incubated for 2 or 5 h in the presence of either 0.1 or 1 microgram/ml hCG or 1 mM monobutyryl cyclic AMP (bcAMP). Neither hCG nor bcAMP stimulated progesterone production by the isolated corpus luteum, despite a sustained high rate of progesterone production by the tissue throughout the incubation period. By contrast, Graafian follicles removed from the same ovaries and incubated under the same conditions responded both to hCG and bcAMP with large increases in progesterone production. To determine whether the cyclic AMP content of the corpus luteum was altered by in vitro exposure to hCG, day 7 and day 11 corpora lutea were incubated for 5 or 15 min with various concentrations of hCG, and cyclic AMP in the tissue was then measured. Even at the highest concentration of hCG tested (10 micrograms/ml), the cyclic AMP content of the corpus luteum was unaltered.(ABSTRACT TRUNCATED AT 250 WORDS)
From institution to foster care: impact on nutritional status. (1987)

Eighty-two clients who were transferred from a residential institution to foster-care homes were provided nutrition services as part of their Individual Program Plans. Findings of the nutrition assessment and intervention were analyzed to document the impact of deinstitutionalization and nutrition services. Nutrition-related problems identified were closely associated to the medical problems. More than half of the clients were diagnosed as having seizures and cerebral palsy and were, therefore, at high nutritional risk because of feeding problems and anticonvulsant-induced malnutrition. Forty-three of the 47 clients who were reassessed showed positive changes in height, weight, triceps skinfold thickness, dietary adequacy, and/or biochemical indices.
Distinct Ras Effector Pathways Are Involved in FcεR1 Regulation of the Transcriptional Activity of Elk-1 and NFAT in Mast Cells (1997)

Activation of Ras GTPases is a conserved feature of antigen receptor signaling, including Fc epsilon R1 activation of mast cells. Antigenic cross-linking of the Fc epsilon R1 on mast cells results in secretion of allergic mediators and induction of immediate early and cytokine genes. Here we examine the role of Ras in coupling the Fc epsilon R1 to transcriptional regulation. The transcription factors Elk-1, an immediate early gene regulator and the nuclear factor of activated T cells (NFAT), in the context of the IL-4 gene, are identified as Ras targets in mast cells. Ras mediates diverse effects via its diverse effector pathways, which may include other members of the Ras GTPase family such as RhoA and Rac-1. We observe that Elk-1 and NFAT are targeted by distinct Ras effector pathways in mast cells. Activation of the "classical" Ras/Raf-1/MEK/ ERK cascade is necessary and sufficient for Fc epsilon R1 induction of Elk-1. Ras function is required, but not sufficient for Fc epsilon R1 induction of NFAT. However, activation or inhibition of Ras markedly shifts the antigen dose-response for Fc epsilon R1 induction of NFAT. The effector pathway for Ras activation of NFAT is not Raf-1/MEK. We identify that the Rac-1 GTPase is critical in Fc epsilon R1 regulation of NFAT, acting either in parallel with or as an effector of Ras. These data place Ras in a crucial position in mast cells, regulating disparate nuclear targets. Moreover, we identify that two GTPases, Ras and Rac-1, are important regulators of NFAT, and therefore of cytokine expression in mast cells.
康熙、雍正、乾隆书画艺术及市场价值 (2007)

近些年来，帝王作品受到众多买家追捧，以艺术家名世的宋徽宗不论，清代康熙、雍正、乾隆三代“盛世”之君，日前的拍价也屡创新高，在书画拍卖价格波动时成为风险避风港。帝王作品受到追捧，自然有藏于深富、得之不易的因素，一般藏家鲜有收藏帝王作品的机会，一旦拥有，就会成为一种品位、荣耀的象征。另一方面，历代帝王不少从小就受到书画名家的熏陶，有的甚至受到严格的四书五艺的教育和训练。当了皇帝后，不少仍舞文弄墨，
Mode stability of external cavity diode lasers (2009)

Mode stability is an important performance characteristic of external cavity diode lasers (ECDLs). It has been well established that the continuous mode-hop-free tuning range of a grating-feedback ECDL can be optimized by rotating the grating about a specific pivot location. We show that similar results can be obtained for other more convenient pivot locations by choosing instead the cavity length and grating location. The relative importance of the temperature stability of the diode and of the external cavity is also evaluated. We show that mechanically simple ECDL designs, using mostly standard components, can readily achieve a 35 GHz mode-hop-free tuning range at 780 nm.
<title>Software-based universal demultiplexing: threshold-free energy minimization approach</title> (2001)

Software-based grouping of multiplexed video based on video content, as opposed to the signal generated by multiplexers, is described. The method is based on energy minimization approach. The algorithm automatically determines the amount of multiplexed camera views, and then the frames are grouped with respect to camera views. The algorithm is free of any threshold differences between camera views, and does not depend on the presence of quiet zones. The method also compensates for interference noise, local and global motion, are contrast changes.
Voltage tunable superlattice infrared detector for mid- and long-wavelength detection (2005)

We have designed and fabricated a voltage tunable superlattice (SL) infrared photodetector where the detection wavelength switches from the 3–5μm midwavelength infrared (MWIR) range under negative bias to the 8–12μm long-wavelength infrared (LWIR) range under large positive bias. The structure consists of multiple periods of two different SLs that are separated by undoped blocking barriers on one side and heavily doped layers on the other side. The background-limited temperature with F∕1.2 optics is 110 and 70 K for mid- and long-wavelength detection, respectively. This voltage tunable MWIR/LWIR detector has a performance comparable to those of one-color quantum-well infrared detectors designed for the respective wavelength ranges.
Hajukone (2016)

In comparison to our other senses, there has been relatively little work on how our sense of smell can be effectively utilised in a Human-Computer Interface. We argue that the lack of easy access to 'off-the-shelf' computer controlled scent delivery devices restricts research in this area, and that without understanding what smell can be used for, there is little commercial case to make such devices available. In considering these issues, we have developed Hajukone: a smell delivery device that is both open source and can be built with low technical skills, yet provides high quality olfactory capabilities. We outline the design of Hajukone, showing how it overcomes critical design requirements that have restricted prior research, before outlining our future plans for its development and use.
Contact electrification and lichtenberg figures on insulators (1968)

Contact electrification experiments on insulators have been performed using liquid mercury as a compliant contacting electrode. The experiments show that large amounts of charge can be exchanged between the surfaces; in many cases the charge density is so large that air breakdown occurs when the surfaces are separated. The resulting charge distribution can then be “developed” by electrographic powders. The powder figures formed by developing these charge patterns strongly resemble the well-known Lichtenberg figures reported for discharges over insulators. <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1, 2</sup>
ChemInform Abstract: Synthesis and Structure of Polyspirocyclodimethylsiloxanes. (1987)

Abstract Hydrolysis of the cyclosiloxanes (I) or (III) with a stoichiometric amount of water in the presence of pyridine leads to the formation of the polyspirocyclosiloxanes (II) and (IV) respectively.
Large scale scanning probe microscope: Making the shear-force scanning visible (2010)

We describe a demonstration of a scanning probe microscope with shear-force tuning fork feedback. The tuning fork is several centimeters long, and the rigid fiber is replaced by a toothpick. By scaling this demonstration to visible dimensions the accessibility of shear-force scanning and tuning fork feedback is increased.
Breaking the silicon limit using semi-insulating Resurf layers (2002)

In this paper, we present results on a novel multi-Resurf technique that involves the use of semi-insulating layers, in which the flattening of the electric field profile is achieved by virtue of a small leakage current. Unlike conventional Resurf devices, this technique provides a perfect flattening of the field profile without the requirement of an accurate charge balance. Experimental results show an increase in steady-state breakdown voltage from 19 to 85 V for a device having 4 /spl mu/m drift regions doped at 5e16 cm/sup -3/, with corresponding R/sub on/ below the silicon limit.
Notes on Mammals of the Labrador Interior (1930)

Journal Article Notes on Mammals of the Labrador Interior Get access William Duncan Strong William Duncan Strong Field Museum of Natural History, Chicago, Illinois Search for other works by this author on: Oxford Academic Google Scholar Journal of Mammalogy, Volume 11, Issue 1, 11 February 1930, Pages 1–10, https://doi.org/10.2307/1373779 Published: 11 February 1930
MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses (2009)

Toll/interleukin-1 (TIR)receptor-containing adapters are critical in orchestrating the different signal transduction pathways following Toll-like receptor (TLR) activation. MyD88 adapter-like (Mal), also termed TIRAP, is involved in bridging MyD88 to the receptor complex for TLR-2 and TLR4 signaling in response to bacterial infection. We have previously reported an interaction between Mal and tumor necrosis factor receptor-associated factor 6 (TRAF6) via a TRAF6-binding motif, the disruption of which inhibited TLR-mediated NF-kappaB-luciferase reporter activity. Given the recent report of intracellular TRAM localization promoting sequential signaling in TLR4 responses, we further characterized Mal interaction with TRAF6, the cellular localization, and the outcomes of disrupting this association on TLR inflammatory responses. We found that Mal and TRAF6 directly interact in response to TLR2 and TLR4 stimulation, although membrane localization is not necessary to facilitate interaction. Critically, reconstitution of murine Mal-deficient macrophages with MalE190A, containing a mutation within the TRAF6-binding motif, fails to reconstitute the proinflammatory response to TLR2 and TLR4 ligands compared with wild type Mal. Furthermore, Mal interaction with TRAF6 mediates Ser phosphorylation of the p65 subunit of NF-kappaB and thus controls transcriptional activation but not nuclear translocation of NF-kappaB. This study characterizes the novel role for Mal in facilitating the direct recruitment of TRAF6 to the plasma membrane, which is necessary for TLR2- and TLR4-induced transactivation of NF-kappaB and regulation of the subsequent pro-inflammatory response.