gebhart/patrepeval huggingface dataset:
IX.—NEW BOOKS (1918)

Journal Article IX.—NEW BOOKS Get access Kant's Teleologie. Door C. PEKELHARING, Noordhoff, Groningen. 1916. Pp. viii, 243. J. L. MCL J. L. MCL Search for other works by this author on: Oxford Academic Google Scholar Mind, Volume XXVII, Issue 1, 1918, Pages 114–115, https://doi.org/10.1093/mind/XXVII.1.114 Published: 01 January 1918
The Detour Polynomials of Ladder Graphs (2012)

The detour distance between two distinct vertices and of a connected graph is the length of a longest path in. The detour index of is defined by, and the detour polynomial of is . The detour indices and detour polynomials of some ladder graphs are obtained in this paper.
Nucleotidyl Cyclase Activity of Soluble Guanylyl Cyclase α<sub>1</sub>β<sub>1</sub> (2011)

Soluble guanylyl cyclase (sGC) regulates several important physiological processes by converting GTP into the second-messenger cGMP. sGC has several structural and functional properties in common with adenylyl cyclases (ACs). Recently, we reported that membranous ACs and sGC are potently inhibited by 2',3'-O-(2,4,6-trinitrophenyl)-substituted purine and pyrimidine nucleoside 5'-triphosphates. Using a highly sensitive high-performance liquid chromatography-tandem mass spectrometry method, we report that highly purified recombinant sGC of rat possesses nucleotidyl cyclase activity. As opposed to GTP, ITP, XTP and ATP, the pyrimidine nucleotides UTP and CTP were found to be sGC substrates in the presence of Mn(2+). When Mg(2+) is used, sGC generates cGMP, cAMP, cIMP, and cXMP. In conclusion, soluble "guanylyl" cyclase possesses much broader substrate specificity than previously assumed. Our data have important implications for cyclic nucleotide-mediated signal transduction.
Bit rate reduction for digital TV (1991)

The aim of this study was to examine the effect of dietary restrictions on compliance with Haemoccult screening for colorectal carcinoma. One-hundred-and-fifty-three individuals were randomly allocated to perform Haemoccult tests with or without dietary restrictions, over 3 or 6 days. Those who failed to return completed tests within 6 weeks were sent a reminder letter. A small but significant improvement in compliance when testing over a 3-day period has been previously demonstrated but this difference was not seen in this study because of the small sample size. Overall, 72.8% compliance was achieved in those who were not asked to exclude certain foods during the test period compared with 51.8% in those in whom dietary restriction was requested (chi 2 = 7.45, P < 0.01). In a British population compliance with Haemoccult screening is adversely affected by the imposition of dietary restrictions.
Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes (2014)

It is hypothesized that allergens are at the borderline of self and non-self and, through as yet elusive circumstances, mount a Th2 response for allergic sensitization. The major birch pollen allergen Bet v 1 is considered the prototype for the PR-10 protein family causing respiratory allergy. Here, we give structural evidence that Bet v 1 is a lipocalin-like protein with a striking structural resemblance to human lipocalin 2. Lipocalin 2 is highly expressed in the lung where it exerts immunoregulatory functions dependent on being loaded with siderophore-bound iron (holo-form) or not (apo-form). We demonstrate that similar to lipocalin 2, Bet v 1 is capable of binding iron via catechol-based siderophores. Thereby, calculated Kd values of 66 nm surpassed affinities to known ligands nearly by a power of 10. Moreover, we give functional evidence of the immunomodulatory capacity of Bet v 1 being dependent on its iron-loaded state. When incubated to human immune cells, only the apo-form of Bet v 1, but not the holo-form, was able to promote Th2 cells secreting IL13. These results provide for the first time a functional understanding on the allergenicity of Bet v 1 and a basis for future allergen immunotherapies counteracting Th2 immune responses on a molecular basis.
Reconstruction of vector and tensor fields from sampled discrete data (1999)

We construct atomic spaces S ⊂ L2(R, T 1 1 ) that are appropriate for the representation and processing of discrete tensor field data. We give conditions for these spaces to be well defined, atomic subspaces of the Wiener amalgam space W (C,L2(R, T 1 1 )) which is locally continuous and globally L2. We show that the sampling or discretization operator R from S to l2(Z, T 1 1 ) is a bounded linear operator. We introduce the dilated spaces S∆ = D∆ S parametrized by the coarseness ∆, and show that the discretization operator is also bounded with a bounded inverse for any ∆ ∈ Zn. This allows us to represent discrete tensor field data in terms of continuous tensor fields in S∆, and to obtain continous representations with fast filtering algorithms.
A Novel Approach for the Production of Nitrogen Doped TiO<sub>2</sub> Nanoparticles (2015)

In this study a visible light active nitrogen doped nanostructure titanium dioxide was synthesized by a simple mixing of Degussa P25 and Urea powder and further thermal treatment under the adequate conditions. Photocatalytic activity of produced nanoparticles was verified by providing of photocatalytic degradation of phenol aqueous solution. Mainly this work was focused on the investigation of the following effects: urea concentration, temperature treatment, catalyst loading and initial phenol concentration. Kinetics study was also carried out. The approach appears to be successful and may be applied for example during the photocatalytic treatment of wastewater streams without or with a limited aid of UV lamps. Copyright © 2015, AIDIC Servizi S.r.l.
Railgun recoil forces cannot be modeled as gas pressure (1997)

This letter discusses the failure of the Lorentz force law to locate the recoil action in railguns. Ampere's force law makes predictions which agree with experiment.
Loss of prothrombin and of factor Xa-factor Va interactions upon inactivation of factor Va by activated protein C. (1984)

Activated factor V (factor Va) is composed of two nonidentical subunits which can be dissociated on chelation of the bound Ca2+ with EDTA. The isolated subunits can be recombined in the presence of Ca2+ to form factor Va. The factor Va heavy chain (Mr = 94,000) binds to prothrombin in a specific and Ca2+-independent fashion. Following inactivation of either factor Va or the factor Va heavy chain by limited proteolysis with activated protein C, factor Va no longer binds to the immobilized prothrombin. Factor Va also binds specifically to (p-amidinophenyl)-methanesulfonyl-factor Xa-Affi-Gel 15. However, neither isolated subunit binds to this column. Factor Va inactivated by activated protein C is no longer retained by the factor Xa column. This data suggests that both subunits are required for optimal factor Va-factor Xa interaction and that inactivation of factor Va with activated protein C reduces the affinity of factor Va for both prothrombin and factor Xa.
MUTE-AES: a multiprocessor architecture to prevent power analysis based side channel attack of the AES algorithm (2008)

Side channel attack based upon the analysis of power traces is an effective way of obtaining the encryption key from secure processors. Power traces can be used to detect bitflips which betray the secure key. Balancing the bitflips with opposite bitflips have been proposed, by the use of opposite logic. This is an expensive solution, where the balancing processor continues to balance even when encryption is not carried out in the processor.We propose, for the first time, a multiprocessor algorithmic balancing technique to prevent power analysis of a processor executing an AES cryptographic program, a popular encryption standard for embedded systems. Our technique uses a dual processor architecture where two processors execute the same program in parallel, but with complementary intermediate data, thus balancing the bitflips. The second processor works in conjunction with the first processor for balancing only when the AES encryption is performed, and both processors carry out independent tasks when no encryption is being performed.Accessing the encryption key or the input data by the first processor begins the obfuscation by the second processor. To stop the encryption by the second processor, we use a novel signature detection technique, which detects the end of the encryption automatically. The multiprocessor balancing approach (MUTEAES) proposed here reduces performance by 0.42% and increases the size of the hardware by 2X (though reduces to 0.1% when no encryption is being performed). We show that Differential Power Analysis (DPA) fails when our technique is applied to AES. We further illustrate, that by the use of this balancing strategy, the adversary is left with noise from the power profile with little useful information.
Stress and Displacement Distributions on Cylindrical Roller Bearing Rings Using FEM<sup>#</sup> (2008)

Abstract Stress and displacement distributions on inner and outer rings of cylindrical roller bearings are investigated using the finite element (FE) method. FE models are solved by considering the interactions of steel shaft, inner ring, rollers, outer ring, and outer cage using ANSYS. The mesh convergence rates of FE models are investigated and the optimum number of elements is selected in the models. The load distributions on rollers are determined. The radial, tangential, and von Mises stresses are plotted along the inner and outer faces of the inner and outer rings. The radial, tangential, and total displacements are also investigated. FE solutions are validated with experiments and available analytic solutions.
Identification of the Missing Component in the Mitochondrial Benzamidoxime Prodrug-converting System as a Novel Molybdenum Enzyme (2006)

Amidoximes can be used as prodrugs for amidines and related functional groups to enhance their intestinal absorption. These prodrugs are reduced to their active amidines. Other N-hydroxylated structures are mutagenic or responsible for toxic effects of drugs and are detoxified by reduction. In this study, a N-reductive enzyme system of pig liver mitochondria using benzamidoxime as a model substrate was identified. A protein fraction free from cytochrome b5 and cytochrome b5 reductase was purified, enhancing 250-fold the minor benzamidoxime-reductase activity catalyzed by the membrane-bound cytochrome b5/NADH cytochrome b5 reductase system. This fraction contained a 35-kDa protein with homologies to the C-terminal domain of the human molybdenum cofactor sulfurase. Here it was demonstrated that this 35-kDa protein contains molybdenum cofactor and forms the hitherto ill defined third component of the N-reductive complex in the outer mitochondrial membrane. Thus, the 35-kDa protein represents a novel group of molybdenum proteins in eukaryotes as it forms the catalytic part of a three-component enzyme complex consisting of separate proteins. Supporting these findings, recombinant C-terminal domain of the human molybdenum cofactor sulfurase exhibited N-reductive activity in vitro, which was strictly dependent on molybdenum cofactor.
El CNJC dóna suport al dret a decidir (2012)

En su 35a Assemblea General Ordinaria, el Consell Nacional de la Joventut de aprovo la resolucion Suport a la declaracio de sobirania i el dret a decidir del poble de Catalunya
Simultaneous Excitation of Multiple-Input/Multiple-Output CFD-Based Unsteady Aerodynamic Systems (2008)

A significant improvement to the development of computational-fluid-dynamics-based unsteady aerodynamic reduced-order models is presented. The improvement involves the simultaneous excitation of the structural modes of the computational-fluid-dynamics-based unsteady aerodynamic system. This improvement enables the computation of the unsteady aerodynamic state-space model using a single computational fluid dynamics execution, independent of the number of structural modes. Two new types of input functions are presented that can be used for the simultaneous excitation of the unsteady aerodynamic system via the excitation of the structural modes. Results are presented for a semispan configuration using the CFL3Dv6.4 code.
Transactions Briefs An Algorithmic and Novel Design of a Leading Zero Detector Circuit: Comparison with Logic Synthesis (1994)

Abstmet-A novel way of implementing the Leading Zero Detector (LZD) circuit is pmsented. The implementation is bad on an algorithmic approach resulting in a modular and scalable circuit for any number of bits. We designed a 32 and 64 bit leading zero detector circuit in CMOS and ECL technology. The CMOS version was designed using both logic synthesis and an algorithmic approach. The algorithmic implementation is compnred with the results obtained using modern logic synthesis tools in the same 0.6 pm CMOS technology. The implementation based on an dgorithmic approach showed an advantage compared to the results produced by the logic synthesis. ECL implementation of the 64 bit LZD circuit was simulated to perform in under 200 pS for nominal speed. I. INTRODUCTION In any floating-point processor normalization is a required operation. It consists of an appropriate left shift until the first nonzero digit is in the left-most position. The amount of shift is determined by counting the number of zero digits from the left-most position until the first nonzero digit is reached. The exponents are appropriately decremented for the shift amount. The normalization is usually performed before storing the numbers in the register file (memory), commonly referred to as post-normalization, and referred to as prenormalization before the operation is performed. In both cases, the special circuit implemented (in hardware) to detect the number of leading zeros is referred to as a Leading Zero Detector (LZD).
Dynamic O-GlcNAc cycling at promoters of <i>Caenorhabditis elegans</i> genes regulating longevity, stress, and immunity (2010)

Nutrient-driven O-GlcNAcylation of key components of the transcription machinery may epigenetically modulate gene expression in metazoans. The global effects of GlcNAcylation on transcription can be addressed directly in C. elegans because knockouts of the O-GlcNAc cycling enzymes are viable and fertile. Using anti-O-GlcNAc ChIP-on-chip whole-genome tiling arrays on wild-type and mutant strains, we detected over 800 promoters where O-GlcNAc cycling occurs, including microRNA loci and multigene operons. Intriguingly, O-GlcNAc-marked promoters are biased toward genes associated with PIP3 signaling, hexosamine biosynthesis, and lipid/carbohydrate metabolism. These marked genes are linked to insulin-like signaling, metabolism, aging, stress, and pathogen-response pathways in C. elegans. Whole-genome transcriptional profiling of the O-GlcNAc cycling mutants confirmed dramatic deregulation of genes in these key pathways. As predicted, the O-GlcNAc cycling mutants show altered lifespan and UV stress susceptibility phenotypes. We propose that O-GlcNAc cycling at promoters participates in a molecular program impacting nutrient-responsive pathways in C. elegans, including stress, pathogen response, and adult lifespan. The observed impact of O-GlcNAc cycling on both signaling and transcription in C. elegans has important implications for human diseases of aging, including diabetes and neurodegeneration.
Sequence of the Spike Srotein of the Porcine Epidemic Diarrhoea Virus (1994)

The complete sequence of the spike (S) gene of the Br1/87 isolate of porcine epidemic diarrhoea virus (PEDV) was determined from cDNA clones. The predicted polypeptide was 1383 amino acids long, contained 29 potential N-linked glycosylation sites and showed structural features similar to those of the coronavirus spike protein. The PEDV S protein, like that of the members of the transmissible gastroenteritis virus (TGEV)-related subset, lacks a proteolytic site to yield cleaved amino and carboxy subunits S1 and S2. Viral polypeptide species of the expected M(r), i.e. 170K/190K, were observed in PEDV-infected cells. Sequence comparison confirmed that, within the subset, PEDV was most closely related to the human respiratory coronavirus HCV 229E. However, PEDV S protein has an additional 250 residue N-terminal domain which is absent from HCV 229E and porcine respiratory coronavirus, the respiratory variant of TGEV. Alignment of the S1 regions revealed a second domain of about 90 residues with increased sequence divergence which might possibly express virus-specific determinants.
Neurotrophin and Trk expression by cells of the human lamina cribrosa following oxygen-glucose deprivation (2004)

In vitro conditions that mimic ischemia increase the expression and secretion of neurotrophins by cells from the ONH. Increased Trk A expression and activation in LC cells following OGD and in ONH astrocytes following recovery from OGD suggest autocrine/paracrine neurotrophin signaling could be a response to ONH ischemia in POAG. Also, the increase in NGF, BDNF and NT-3 protein expression and NGF secretion following OGD also suggest LC cells and ONH astrocytes may be a paracrine source of neurotrophins for RGCs.
Mobility Aware Distributed Topology Control in Mobile Ad-Hoc Networks with Model Based Adaptive Mobility Prediction (2007)

Topology control in mobile ad-hoc networks allows better spatial reuse of the wireless channel and control over network resources. Topology control algorithms tend to optimize network power usage by keeping the topology connected. However, few efforts have focused on the issue of topology control with mobility. One of the most efficient mobility aware topology control protocols is the "mobility aware distributed topology control protocol". The major problem with this protocol is the future distance predictor which uses mobility prediction to estimate the future distance of neighboring nodes. The efficiency of this estimator varies in presence of different mobility models, sampling rates and different speed ranges. In this paper, we introduce an adaptive mobility prediction method that uses learning automaton to estimate the coefficients of a simple adaptive filter in order to predict the future distance of two neighboring nodes. We evaluated this estimator in the mobility aware distributed topology control protocol. Simulation results show significant improvement in accuracy of the future distance prediction and reduction in power consumption of each node.
A systematic literature review of automated clinical coding and classification systems (2010)

Clinical coding and classification processes transform natural language descriptions in clinical text into data that can subsequently be used for clinical care, research, and other purposes. This systematic literature review examined studies that evaluated all types of automated coding and classification systems to determine the performance of such systems. Studies indexed in Medline or other relevant databases prior to March 2009 were considered. The 113 studies included in this review show that automated tools exist for a variety of coding and classification purposes, focus on various healthcare specialties, and handle a wide variety of clinical document types. Automated coding and classification systems themselves are not generalizable, nor are the results of the studies evaluating them. Published research shows these systems hold promise, but these data must be considered in context, with performance relative to the complexity of the task and the desired outcome.
Design and control of a disk-type integrated motor-bearing system (2002)

A disk-type integrated motor-bearing system having axial magnetic flux is newly invented and its design, analysis, and control methods are presented. Sinusoidal motoring currents to four symmetrically placed winding groups produce a torque, whereas control currents of the same magnitude but opposite signs added to the opposite winding groups create radial forces. The control currents are intended to break force symmetry, resulting in unbalanced radial forces. The system employs two stators not only to effectively remove the rotational frequency modulation effect in the radial control forces, but also to reduce the torque ripple. It is shown that the prototype integrated motor-bearing system built in the laboratory succeeds in stable radial direction control and operation of the rotor.
Tactile sensing over articulated joints with stretchable sensors (2013)

Biological organisms benefit from tactile sensing across the entire surfaces of their bodies. Robots may also be able to benefit from this type of sensing, but fully covering a robot with robust and capable tactile sensors entails numerous challenges. To date, most tactile sensors for robots have been used to cover rigid surfaces. In this paper, we focus on the challenge of tactile sensing across articulated joints, which requires sensing across a surface whose geometry varies over time. We first demonstrate the importance of sensing across joints by simulating a planar arm reaching in clutter and finding the frequency of contact at the joints. We then present a simple model of how much a tactile sensor would need to stretch in order to cover a 2 degree-of-freedom (DoF) wrist joint. Next, we describe and characterize a new tactile sensor made with stretchable fabrics. Finally, we present results for a stretchable sleeve with 25 tactile sensors that covers the forearm, 2 DoF wrist, and end effector of a humanoid robot. This sleeve enabled the robot to reach a target in instrumented clutter and reduce contact forces.
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism (2010)

Recent studies showed that germ-free (GF) mice are resistant to obesity when consuming a high-fat, high-carbohydrate Western diet. However, it remains unclear what mechanisms are involved in the antiobesity phenotype and whether GF mice develop insulin resistance and dyslipidemia with high-fat (HF) feeding. In the present study, we compared the metabolic consequences of HF feeding on GF and conventional (conv) C57BL/6J mice. GF mice consumed fewer calories, excreted more fecal lipids, and weighed significantly less than conv mice. GF/HF animals also showed enhanced insulin sensitivity with improved glucose tolerance, reduced fasting and nonfasting insulinemia, and increased phospho-Akt((Ser-473)) in adipose tissue. In association with enhanced insulin sensitivity, GF/HF mice had reduced plasma TNF-α and total serum amyloid A concentrations. Reduced hypercholesterolemia, a moderate accretion of hepatic cholesterol, and an increase in fecal cholesterol excretion suggest an altered cholesterol metabolism in GF/HF mice. Pronounced nucleus SREBP2 proteins and up-regulation of cholesterol biosynthesis genes indicate that enhanced cholesterol biosynthesis contributed to the cholesterol homeostasis in GF/HF mice. Our results demonstrate that fewer calorie consumption and increased lipid excretion contributed to the obesity-resistant phenotype of GF/HF mice and reveal that insulin sensitivity and cholesterol metabolism are metabolic targets influenced by the gut microbiota.
Novel Topology for a Non-Reciprocal MEMS Filter (2018)

The paper reports the first prototype of a magnetic-free, non-reciprocal 50Ω matched MEMS filter, based on a spatio-temporal modulation of identical resonators. The proposed approach shows similar performances and at least a 7 times smaller area if compared with a dual ladder filter. For these reasons, the novel topology eliminates all trade offs among performances, area, fabrication complexity and temperature compensation processes which restrict any MEMS filters. Experimental data has shown 12MHz BW3dB with insertion loss of 5.6dB and an isolation peak equal to -20dB, by exploiting 6 1GHz FBARs with 6.5% k <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</sub> <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and 320 as quality factor.