gebhart/patrepeval huggingface dataset:
An optical centralized shared-bus architecture demonstrator for microprocessor-to-memory interconnects (2003)

An architecture demonstrator of an innovative interconnect scheme called the optical centralized shared-bus is presented. This architecture retains the advantages of shared-bus topology while at the same time specifying a uniform interface between the electrical and the optical backplane layers in contrast to other proposed architectures. For the first time, a fanout equalized optical backplane bus is demonstrated. In this architecture demonstrator, the data paths required for the microprocessor-to-memory interconnects are provided by the optical centralized shared-bus. The optoelectronic interface modules are optimized to support data rates up to 1.25 Gb/s. The objective of this microprocessor-to-memory interconnects demonstration is to ensure the feasibility of applying this innovative architecture in real systems.
A Compressed sensing analog-to-information converter with edge-triggered SAR ADC Core (2012)

This paper presents the design and implementation of an analog-to-information converter (AIC) based on compressed sensing. The core of the AIC is an edge-triggered charge-sharing SAR ADC. Compressed sensing is achieved through random sampling and asynchronous successive approximation conversion using the ADC core. Implemented in 90nm CMOS, the prototype SAR ADC core achieves a maximum sample rate of 9.5MS/s, an ENOB of 9.3 bits, and consumes 550μW from a 1.2V supply. Measurement results of the compressed sensing AIC demonstrate effective sub-Nyquist random sampling and reconstruction of signals with sparse frequency support suitable for wideband spectrum sensing applications. When accounting for the increased input bandwidth compared to Nyquist, the AIC achieves an effective FOM of 10.2fJ/conversion-step.
Monocyte Chemoattractant Protein-1 (MCP-1) Regulates Macrophage Cytotoxicity in Abdominal Aortic Aneurysm (2014)

Our data suggest that MCP-1-primed macrophages are more cytotoxic. MCP-1 appears to modulate macrophage cytotoxicity by increasing the level of membrane bound FasL. Thus, we showed that MCP-1-primed macrophages kill SMCs through a FasL/Fas-Caspase8-RIP1 mediated mechanism.
Reynolds-Averaged Navier–Stokes Equations for Turbulence Modeling (2009)

The approach of Reynolds-averaged Navier–Stokes equations (RANS) for the modeling of turbulent flows is reviewed. The subject is mainly considered in the limit of incompressible flows with constant properties. After the introduction of the concept of Reynolds decomposition and averaging, different classes of RANS turbulence models are presented, and, in particular, zero-equation models, one-equation models (besides a half-equation model), two-equation models (with reference to the tensor representation used for a model, both linear and nonlinear models are considered), stress-equation models (with reference to the pressure-strain correlation, both linear and nonlinear models are considered) and algebraic-stress models. For each of the abovementioned class of models, the most widely-used modeling techniques and closures are reported. The unsteady RANS approach is also discussed and a section is devoted to hybrid RANS/large methods.
Interleukin-18/Interleukin-18 Binding Protein Signaling Modulates Ischemia-Induced Neovascularization in Mice Hindlimb (2002)

Identification of factors that may stimulate ischemia-induced neovascularization without increasing atherosclerotic plaque progression is of major therapeutic importance. We hypothesized that interleukin-18 binding protein (IL-18BP), a major antiinflammatory protein with plaque-stabilizing activities, may affect the neovascularization in mice ischemic hindlimb. Ischemia was produced by artery femoral occlusion in mice that were subjected to in vivo intramuscular electrotransfer of either an empty plasmid or a murine IL-18BP plasmid. Angiographic score, capillary density (CD31 staining), and laser Doppler perfusion data at day 28 showed significant improvement in ischemic/nonischemic leg ratio by respectively 1.6-, 1.4-, and 1.5-fold in IL-18BP-treated mice compared with controls (P<0.01). This was associated with a significant 2-fold increase in both vascular endothelial growth factor (VEGF) and phospho-Akt protein content in the ischemic hindlimb of IL-18BP-treated mice (P<0.05). Similar results were obtained in IL-18-deficient mice. Because bone marrow-derived endothelial progenitor cells (BM-EPCs) are involved in postnatal vasculogenesis, EPCs were isolated and cultivated from bone marrow mononuclear cells. IL-18BP treatment led to a significant 1.8-fold increase in the percentage of BM-EPCs characterized as cells positive for both AcLDL-Dil and von Willebrand factor (P<0.001). In conclusion, IL-18BP stimulates ischemia-induced neovascularization in association with an activation of VEGF/Akt signaling and an increase in BM-EPCs mobilization and differentiation. Our findings strongly suggest a major antiangiogenic role of endogenous IL-18 in postischemic injury.
Fair bandwidth sharing among virtual networks: a capacity resizing approach (2002)

Virtual private networks (VPN) and link sharing are cost-effective ways of realizing corporate intranets. Corporate intranets will increasingly have to provide integrated services for voice and multimedia traffic. Although packet scheduling algorithms can be used to implement integrated services in link sharing and virtual private networks, their statistical multiplexing gains are limited. We propose a new scheme called stochastic fair sharing (SFS) to carry out fair link sharing and fair sharing among virtual leased links (VLL). In the link sharing environment, capacities allocated to different classes are adjusted dynamically as sessions arrive (or depart). The SFS admission control algorithm decides which sessions to accept and which to reject depending upon the current utilizations and provisioned capacities of the classes. SFS gives protection to classes with low session arrival rate against classes with high session arrival rates by ensuring them a low blocking probability. In the case of multi-hop VLL, capacity resizing requests are sent in the service providers's network which are admission-controlled using SFS. Our simulations indicate that using SFS, the equivalent capacity of virtual links converge to their max-min fair capacity, with a fairness index of 0.97 in extreme situations. The average signaling load of the protocol was found to be reasonable. The scheme is simple to implement, efficient, and robust. The potential applications of SFS are fair and efficient resource sharing in telecommunication networks, ATM networks, virtual private networks (VPN) and integrated services or differentiated services-based IP networks.
Massive gliosis induced by interleukin‐6 suppresses Aβ deposition <i>in vivo:</i> evidence against inflammation as a driving force for amyloid deposition (2009)

Proinflammatory stimuli, after amyloid beta (Abeta) deposition, have been hypothesized to create a self-reinforcing positive feedback loop that increases amyloidogenic processing of the Abeta precursor protein (APP), promoting further Abeta accumulation and neuroinflammation in Alzheimer's disease (AD). Interleukin-6 (IL-6), a proinflammatory cytokine, has been shown to be increased in AD patients implying a pathological interaction. To assess the effects of IL-6 on Abeta deposition and APP processing in vivo, we overexpressed murine IL-6 (mIL-6) in the brains of APP transgenic TgCRND8 and TG2576 mice. mIL-6 expression resulted in extensive gliosis and concurrently attenuated Abeta deposition in TgCRND8 mouse brains. This was accompanied by up-regulation of glial phagocytic markers in vivo and resulted in enhanced microglia-mediated phagocytosis of Abeta aggregates in vitro. Further, mIL-6-induced neuroinflammation had no effect on APP processing in TgCRND8 and had no effect on APP processing or steady-state levels of Abeta in young Tg2576 mice. These results indicate that mIL-6-mediated reactive gliosis may be beneficial early in the disease process by potentially enhancing Abeta plaque clearance rather than mediating a neurotoxic feedback loop that exacerbates amyloid pathology. This is the first study that methodically dissects the contribution of mIL-6 with regard to its potential role in modulating Abeta deposition in vivo.
Behavior of Molybdenum–Vanadium Mixed Oxides in Selective Oxidation and Disproportionation of Toluene (2019)

This study deals with the behavior of molybdenum⁻vanadium (Mo/V) mixed oxides catalysts in both disproportionation and selective oxidation of toluene. Samples containing different Mo/V ratios were prepared by a modified method using tetradecyltrimethylammonium bromide and acetic acid. The catalysts were characterized using several techniques: nitrogen adsorption⁻desorption isotherms, X-Ray diffraction (XRD), ammonia temperature-programmed desorption (TPD-NH₃), temperature-programmed reduction by hydrogen (H₂-TPR), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, Fourier-transform infrared-spectroscopy (FTIR) and ultraviolet-visible spectroscopies (UV⁻VIS). The XRD results evidenced the presence of orthorhombic α-MoO₃ and V₂O₅ phases, as well as monoclinic β-MoO₃ and V₂MoO₈ phases, their abundance depending on the Mo to V ratio, while the TPD-NH₃ emphasized that, the total amount of the acid sites diminished with the increase of the Mo loading. The TPR investigations indicated that the samples with higher Mo/V ratio possess a higher reducibility. The main findings of this study led to the conclusion that the presence of strong acid sites afforded a high conversion in toluene disproportionation (Mo/V = 1), while a higher reducibility is a prerequisite to accomplishing high conversion in toluene oxidation (Mo/V = 2). The catalyst with Mo/V = 1 acquires the best yield to xylenes from the toluene disproportionation reaction, while the catalyst with Mo/V = 0.33 presents the highest yield to benzaldehyde.
Slot-Line Filters and Couplers (1970)

The slot-transmission line on a dielectric substrate has many possible microwave circuit applications. This paper presents experimental data concerning the performance of bandpass and bandstop filters and a hybrid coupler; the work described was performed at S-band frequencies using the single substrate slot line geometry. Also included are theoretical data concerning the slot-line wavelength and characteristic impedance for the case of the slot-line configuration having dielectric material above and below the metsllization, the so-called slot-line "sandwich."
Inverted-hook occipital clamp system in occipitocervical fixation (2002)

The authors describe an occipitocervical fixation procedure in which they use inverted occipital hooks inserted through a burr hole drilled in the squamous part of the occipital bone. Fifteen patients with unstable lesions of the occipitocervical junction underwent occipitocervical internal fixation. The mean follow-up period was 21 months (range 2-63 months). No implant failed, and postoperative immobilization was not required. The placement of a posterior occipitocervical graft (for which fusion is uncertain) can be avoided in certain conditions.
To kill or be killed: how viruses interact with the cell death machinery (2010)

A virus (from the Latin virus meaning toxin or poison) is a small infectious agent that can only replicate inside the cells of another organism. Viruses are found wherever there is life and have probably existed since living cells first evolved. Viruses do not have their own metabolism and require a host cell to make new products. The range of structural and biochemical (i.e., cytopathic) effects that viruses have on the host cell is extensive. Most viral infections eventually result in the death of the host cell. The causes of death include cell lysis, alterations to the cell's surface membrane and various modes of programmed cell death. Some viruses cause no apparent changes to the infected cell. Cells in which the virus is latent and inactive show few signs of infection and often function normally. This causes persistent infection and the virus is often dormant for many months or years. Some viruses can cause cells to proliferate without causing malignancy, whereas others are established causes of cancer. Human organisms use a genetically controlled cell death programme that prevents the spreading of viral infection and kills the virus. Between 19 and 21 November 2009, with sponsorship from the Journal of Internal Medicine, the Swedish Research Foundation and the Swedish Cancer Society hosted a conference in Stockholm entitled: 'To kill or to be killed. Viral evasion strategies and interference with cell death machinery'. Four comprehensive reviews from this conference are presented in this issue of the Journal of Internal Medicine. These reviews include descriptions of: the modulation of host innate and adaptive immune defenses by cytomegalovirus; the impact of gamma-chain family cytokines on T cell homoeostasis in HIV-1 infection and the therapeutic implications; approaches to killing tumours by depriving them of the mechanisms for detoxification; and viral strategies for the evasion of immunogenic cell death.
Electrochemical Redox Catalysis for Electrochemical Dehydrogenation of Liquid Hydrogen Carrier Fuels for Energy Storage and Conversion (2013)

The application of redox catalysis to the electrochemical dehydrogenation of organic molecules is of interest for a hybrid flow battery/fuel cell system for energy storage. The process of redox catalysis has been known and well studied theoretically and experimentally for several decades. Studies of redox catalysis can be instrumental in determining mechanistic aspects of electrochemical reactions and in measuring basic thermodynamic and kinetic parameters. Redox catalysis has the ability to reduce the overpotential of the dehydrogenation reaction used in such a system as well as to alter the course of the reaction to achieve higher efficiencies. The mechanism of catalysis can involve an ECE-type reaction or a CEE-type reaction. In either case the acid-base chemistry of the medium is critical. Preliminary results of catalytic current measurements as a function of redox catalyst, base concentration, and base strength are described along with possible reaction mechanisms.
Transactional Value Prediction (2009)

This workshop paper explores some ideas for value prediction and data speculation in hardware transactional memory. We present these ideas in the context of false sharing, at the cache line level, within hardware transactions. We distinguish between coherence conflicts, which may result from false sharing, from true data conflicts, which we call transactional conflicts. We build on some of the ideas of Huh et al. [1] to speculate in the presence of coherence conflicts, assuming no true data conflicts. We then validate data before committing. This dual speculation avoids aborting and restarting many transactions that conflict through false sharing. We show how these ideas, which we call Transactional Value Prediction, can be applied to a conventional best-effort hardware transactional memory. Our preliminary model, β-TVP, does not alter the underlying cache coherence protocol beyond what is already present in hardware transactional memory. β-TVP requires only minor, processor-local modifications to a conventional best-effort hardware transactional memory. Simple benchmarks show that β-TVP can dramatically increase throughput in the presence of false sharing, while incurring little overhead in its absence. 1.
Occurrence of the Isoflavone Afromosin in Cabreuva Wood<sup>1</sup> (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOccurrence of the Isoflavone Afromosin in Cabreuva Wood1Jeffrey B. Harborne, Otto Richard Gottlieb, and Mauro Taveira MagalhãesCite this: J. Org. Chem. 1963, 28, 3, 881–882Publication Date (Print):March 1, 1963Publication History Published online1 May 2002Published inissue 1 March 1963https://pubs.acs.org/doi/10.1021/jo01038a522https://doi.org/10.1021/jo01038a522research-articleACS PublicationsRequest reuse permissionsArticle Views101Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Defect size distribution in VLSI chips (1990)

VLSI patterns consisting of parallel lines of polysilicon with different spacings have been electrically tested. The number of observed shorts was found to be related to the line spacings by using an analytical model for the defect sensitive pattern areas. The distribution of defect sizes in the range from 0.5 to 1.4 mu m is proportional to x/sup -3/. The exponent value agrees with earlier distribution studies concerning defects several micrometers in size.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
<b>6-Methylenetetracyclines. III.<sup>1</sup> Preparation and Properties</b><sup>2</sup> (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT6-Methylenetetracyclines. III.1 Preparation and Properties2Robert K. Blackwood, John J. Beereboom, Hans H. Rennhard, M. Schach. von Wittenau, and Charles R. StephensCite this: J. Am. Chem. Soc. 1963, 85, 24, 3943–3953Publication Date (Print):December 1, 1963Publication History Published online1 May 2002Published inissue 1 December 1963https://doi.org/10.1021/ja00907a010RIGHTS & PERMISSIONSArticle Views292Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
ChemInform Abstract: Synthesis and Application of Some New Oxazole Derivatives as Antimicrobial Agents. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Synthesis and [4 + 2]-Cycloadditions of<i>N</i>-Phenylsulfonyl-3-vinylindole (1986)

1-Phenylsulfonyl-3-vinylindole can be prepared in good yield from the 3-ethyl derivative by a two-step bromination dehydrobromination sequence, As a 1,3-diene it undergoes [4+2]-cycloadditions with N-phenylmaleimide, p-benzoquinone, and dialkyl acetylenedicarboxylates to give derivatives of the 1,2,3,3a,4,5,10,10b-octahydropyrrolo[3,4-a]carbazole, 1,4,4a,5,6,11b-hexahydro-11H-benzo[a]carbazole, and carbazole ring systems, respectively.
Transport Properties of a Classical One-Dimensional Kicked Billiard Model (2000)

We study a classical 1-dimensional kicked billiard model and investigate its transport behavior. The roles played by the two system parameters α and K, governing the direction and strength of the kick, respectively, are found to be quite crucial. For the perturbations which are not strong, i.e. K < 1, we find that as the phase parameter α changes within its range of interest from -π/2 to π/2, the phase space is in turn characterized by the structure of a prevalently connected stochastic web (-π/2 ⩽ α < 0), local stochastic webs surrounded by a stochastic sea (0 < α < π/2) and the global stochastic sea (α = π/2). Extensive numerical investigations also indicate that the system's transport behavior in the irregular regions of the phase space for K < 1 has a dependence on the system parameters and the transport coefficient D can be expressed as D ≈ D0(α)Kf(α). For strong kicks, i.e. K ≫ 1, the phase space is occupied by the stochastic sea, and the transport behavior of the system seems to be similar to that of the kicked rotor and independent of α.
Configuration as a Service in Multi-Tenant Enterprise Resource Planning System (2014)

Enterprise resource planning (ERP) systems are the organizations tickets to the global market. Thus, organizations can manage and coordinate all functions, processes, resources and data from different departments by a single software. However, many organizations consider the cost of traditional ERP is expensive and look for alternative affordable solutions within their budget. One of these alternative solutions is providing ERP over a software as a service (SaaS) model. A key feature of any SaaS system is the multi-tenancy architecture where multiple customers (tenants) share the system software. However, the SaaS developers accommodate each tenant's unique requirements by allowing tenant-level customization or configuration. While customization requires source code changes and in most cases a programming experience, the configuration process allows user to change many features within a pre-defined scope in an easy and controlled manner. Although literature provides many techniques to accomplish the configuration process in different SaaS systems, the nature and complexity of SaaS ERP are merely described in previous researches. Thus, this research is built on strong knowledge regarding the configuration in SaaS to define specifically the configuration borders in SaaS ERP and to design a configuration service with the consideration of the different configuration aspects.