gebhart/patrepeval huggingface dataset:
Checkpoint and Restore of Micro-service in Docker Containers (2015)

In the present days of rapid adoption of micro-service, it is imperative to build a system to support and ensure the high performance and high availability for micro-services. Lightweight virtualization, which we also called container, has the ability to run multiple isolated sets of processes under a single kernel instance. Because of the possibility of obtaining a low overhead comparable to the near-native performance of a bare server, the container techniques, such as openvz, lxc, docker, they are widely used for micro-service In this paper, we present the high availability of micro-service in containers. We investigate capabilities provided by container (docker, openvz) to model and build the Micro-service infrastructure and compare different checkpoint and restore technologies for high availability. Finally, we present preliminary performance results of the infrastructure tuned to the micro-service.
Regulation of glucagon release in mouse α‐cells by K<sub>ATP</sub> channels and inactivation of TTX‐sensitive Na<sup>+</sup> channels (2000)

The perforated patch whole-cell configuration of the patch-clamp technique was applied to superficial glucagon-secreting alpha-cells in intact mouse pancreatic islets. alpha-cells were distinguished from the beta- and delta-cells by the presence of a large TTX-blockable Na+ current, a TEA-resistant transient K+ current sensitive to 4-AP (A-current) and the presence of two kinetically separable Ca2+ current components corresponding to low- (T-type) and high-threshold (L-type) Ca2+ channels. The T-type Ca2+, Na+ and A-currents were subject to steady-state voltage-dependent inactivation, which was half-maximal at -45, -47 and -68 mV, respectively. Pancreatic alpha-cells were equipped with tolbutamide-sensitive, ATP-regulated K+ (KATP) channels. Addition of tolbutamide (0.1 mM) evoked a brief period of electrical activity followed by a depolarisation to a plateau of -30 mV with no regenerative electrical activity. Glucagon secretion in the absence of glucose was strongly inhibited by TTX, nifedipine and tolbutamide. When diazoxide was added in the presence of 10 mM glucose, concentrations up to 2 microM stimulated glucagon secretion to the same extent as removal of glucose. We conclude that electrical activity and secretion in the alpha-cells is dependent on the generation of Na+-dependent action potentials. Glucagon secretion depends on low activity of KATP channels to keep the membrane potential sufficiently negative to prevent voltage-dependent inactivation of voltage-gated membrane currents. Glucose may inhibit glucagon release by depolarising the alpha-cell with resultant inactivation of the ion channels participating in action potential generation.
Inflammatory cytokines induce the expression of basic fibroblast growth factor (bFGF) isoforms required for the growth of Kaposiʼs sarcoma and endothelial cells through the activation of AP-1 response elements in the bFGF promoter (1998)

OSM, IL-1 and TNF-alpha induce KS cell growth by inducing the expression of various bFGF isoforms. Moreover, bFGF production by KS and HUVEC is dependent on the activation of the ERK and JNK cascades, which result in the transcriptional activation of the bFGF promoter.
Highly efficient wideband continuum generation in a single-mode optical fiber by powerful broadband laser pumping (1996)

By pumping a single-mode optical fiber with a powerful broadband nonselective dye laser, we obtain a high-efficiency wideband continuum (530-930 nm) with nonlinear conversion efficiency exceeding 90%. Experimental conditions for a coherent regime of broadband stimulated Raman scattering are created, which in combination with the broadband self-phase modulation and the four-photon parametric processes leads to a spectral broadening and to the continuum formation. The influence of the pump laser spectral linewidth on the nonlinear conversion efficiency is analyzed and investigated by comparative experiments at narrow-band and broadband laser excitations.
RESEARCH ON TRANSFER OF LIQUID WATER ABSORPTION OF KNITTED STRUCTURES FOR SOCKS DESTINATION (2016)

For to adjust the heat, body removes heat. Depending on physical effort, it gives more or less moisture. Moisture removed from the body should be taken from the skin and directed outwards through clothing. This can be due to moisture absorption ability, and because of the capillary effect. This study is a part of a very extensive work on the influence of characteristics and raw materials, knitted structure and density on comfort properties of socks. If a high level of perspiration, moisture liquid, it is important that it be removed as quickly from skin and clothing led outside. From here can evaporate into the environment. This is achieved through the capillary effect of fabrics that may effectively transport moisture. Storage capacity and moisture transfer of a textile depends on the composition and structure. In laboratory conditions, methods for assessing the behavior of textiles against moisture is applied differentially depending on the state humidity: vapor or liquid. With this method of determining the capacity of absorbing water by capillary action, samples have dimensions of 200/200 mm and at one end is immersed in water. The samples knit were made in two versions of the fineness machine.
1,3-Dichloropropene Distribution and Emission after Gelatin Capsule Formulation Application (2009)

The gelatin capsule (gel cap) formulation of 1,3-dichloropropene (1,3-D) was developed as a potential means of reducing 1,3-D emissions. The objective of this study was to determine the distribution, emission, and leaching of 1,3-D after applying the gel cap in soil columns. Comparable 1,3-D soil gas concentrations were obtained between a conventional liquid injection control and the gel cap application with film treatment. When the soil surface was irrigated with 39.6 mm water per day during the first 4 days, 1,3-D soil gas concentration was higher than the film treatments at depths below 20 cm, but lower concentrations were observed at 0-15 cm depth. The application of 1,3-D gel cap relatively reduced total 1,3-D emission by about 41% compared to liquid injection with film cover, and total 1,3-D emission was only 0.13% for 1,3-D gel cap application with 4 days of irrigation without a tarp. The results indicated that 1,3-D gel cap could be a promising new technology for reducing environmental emissions and potential human exposure.
Crystal growth at high temperatures (1949)

S. Zerfoss, L. R. Johnson and P. H. Egli, Discuss. Faraday Soc., 1949, 5, 166 DOI: 10.1039/DF9490500166
A method of automatic hypertext construction from an encyclopedic dictionary of a specific field (1992)

No abstract available.
c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif. (1993)

c-Myc and wild-type p53 have been shown to play important roles in the regulation of cellular proliferation and oncogenic transformation. We have previously shown that the p53 promoter contains a conserved consensus recognition sequence for the basic-helix-loop-helix-containing proteins, identical to the specific binding site for c-Myc/Max heterodimers. Here, we demonstrate that this element, which is required for full promoter activity, is bound by in vitro translated c-Myc/Max heterodimers. Furthermore, we found that in cotransfection assays, c-Myc trans-activates the p53 promoter as well as a hybrid herpes simplex virus-thymidine kinase promoter containing multiple copies of a synthetic p53-derived c-Myc binding site. The p53 promoter deleted of the basic-helix-loop-helix consensus recognition sequence is not trans-activated by c-Myc, thus suggesting that c-Myc trans-activates the p53 promoter through the basic-helix-loop-helix recognition motif. These findings raise the possibility that the p53 gene may be a potential target for trans-activation by c-Myc in vivo.
Impaired K<sup>+</sup>Homeostasis and Altered Electrophysiological Properties of Post-Traumatic Hippocampal Glia (1999)

Traumatic brain injury (TBI) can be associated with memory impairment, cognitive deficits, or seizures, all of which can reflect altered hippocampal function. Whereas previous studies have focused on the involvement of neuronal loss in post-traumatic hippocampus, there has been relatively little understanding of changes in ionic homeostasis, failure of which can result in neuronal hyperexcitability and abnormal synchronization. Because glia play a crucial role in the homeostasis of the brain microenvironment, we investigated the effects of TBI on rat hippocampal glia. Using a fluid percussion injury (FPI) model and patch-clamp recordings from hippocampal slices, we have found impaired glial physiology 2 d after FPI. Electrophysiologically, we observed reduction in transient outward and inward K(+) currents. To assess the functional consequences of these glial changes, field potentials and extracellular K(+) activity were recorded in area CA3 during antidromic stimulation. An abnormal extracellular K(+) accumulation was observed in the post-traumatic hippocampal slices, accompanied by the appearance of CA3 afterdischarges. After pharmacological blockade of excitatory synapses and of K(+) inward currents, uninjured slices showed the same altered K(+) accumulation in the absence of abnormal neuronal activity. We suggest that TBI causes loss of K(+) conductance in hippocampal glia that results in the failure of glial K(+) homeostasis, which in turn promotes abnormal neuronal function. These findings provide a new potential mechanistic link between traumatic brain injury and subsequent development of disorders such as memory loss, cognitive decline, seizures, and epilepsy.
What are Null Hypotheses? The Reasoning Linking Scientific and Statistical Hypothesis Testing (2008)

We should dispense with use of the confusing term null hypothesis in educational research reports. To explain why the term should be dropped, the nature of, and relationship between, scientific and statistical hypothesis testing is clarified by explication of (a) the scientific reasoning used by Gregor Mendel in testing specific hypotheses derived from his general inheritance theory and (b) the statistical reasoning used in applying the chi-square statistic to his experimental data. The Mendel example is followed by application of the same pattern of scientific and statistical reasoning to educational examples. A better understanding of the related, but separate, processes of scientific and statistical hypothesis testing, including the role of scientific hypotheses (i.e., proposed explanations) and scientific predictions (i.e., expected test results), not only reveals why null statistical hypotheses and predictions need not be stated, but also reveals how we can improve the clarity of our research reports and improve the quality of the research reported by insuring that alternative scientific hypotheses and theories are in fact tested. P. Eastwell (personal communication, July 5, 2006) asked readers to consider the confusing and possible misuse of the term null hypothesis in the context of research reports. In Eastwell’s words: We distinguish a prediction (an educated guess about the expected outcome of a test) from a hypothesis (a possible explanation for the observed facts and laws). Does it follow that science education researchers should now dispense with the use of the term null hypothesis in circumstances where it is really a null prediction that is being tested? I think it would be helpful if science education researchers dispensed with use of the term null hypothesis under any circumstances, primarily because the term comes from the field of statistics and its relationship to scientific hypothesis testing is seldom, if ever, made clear. Hence its use in educational research often leads to confusion and may even limit research quality by restricting the number of scientific hypotheses generated and tested. As will become clear in this paper, the term null prediction is also not required. Allow me to attempt to clarify by explicating important similarities and differences between scientific and statistical hypothesis testing in the context of a crucial experiment conducted by Gregor Mendel to test his classic inheritance theory. The example will consider Mendel’s theory, the reasoning behind how he tested it, and how statistical hypothesis testing could have been used to determine the extent to which departures of Mendel’s observed scientific results from his predicted scientific results were due to chance or due to faulty scientific hypotheses. The Mendel example (after Lawson, Oehrtman, & Jensen, 2008, with kind permission of Springer Science and Business Media) will be followed by some educational examples and implications.
Multiblock copolymer behaviour of α-CD/PEO-based polyrotaxanes: towards nano-cylinder self-organization of α-CDs (2008)

The present work demonstrates that α-cyclodextrin/poly(ethylene oxide) (α-CD/PEO)-based polyrotaxanes (PRs) behave as multiblock copolymers. One block type consists of a rod-like tube made of 6 to 7 weakly stacked α-CDs threaded along the PEO chain. The other one is made of a naked PEO segment, i.e. the PR part that is not covered by α-CDs. This multiblock behaviour induces the self-organization of PRs in concentrated solution in dimethyl sulfoxide (DMSO) at room temperature leading to the formation of nano-cylinders. These nano-cylinders consist of assemblies of roughly 60 α-CD rod-like tubes through hydrogen bonding. Moreover, crystallites of naked PEO segments are formed since PEO is in poor solvent conditions (DMSO) at room temperature. Furthermore, the formation of α-CD nano-cylinders as well as of naked PEO segment crystallites leads to physical gelation of PRs in DMSO.
Human POLB Gene Is Mutated in High Percentage of Colorectal Tumors (2012)

Previous small scale sequencing studies have indicated that DNA polymerase β (pol β) variants are present on average in 30% of human tumors of varying tissue origin. Many of these variants have been shown to have aberrant enzyme function in vitro and to induce cellular transformation and/or genomic instability in vivo, suggesting that their presence is associated with tumorigenesis or its progression. In this study, the human POLB gene was sequenced in a collection of 134 human colorectal tumors and was found to contain coding region mutations in 40% of the samples. The variants map to many different sites of the pol β protein and are not clustered. Many variants are nonsynonymous amino acid substitutions predicted to affect enzyme function. A subset of these variants was found to have reduced enzyme activity in vitro and failed to fully rescue pol β-deficient cells from methylmethane sulfonate-induced cytotoxicity. Tumors harboring variants with reduced enzyme activity may have compromised base excision repair function, as evidenced by our methylmethane sulfonate sensitivity studies. Such compromised base excision repair may drive tumorigenesis by leading to an increase in mutagenesis or genomic instability.
Automatic Plotting of Electrostatic Fields (1948)

An apparatus is described by means of which plots of the equipotentials of two-dimensional fields may be made automatically from models of the electrodes. The usual electrolytic tank method has been extended by the addition of a servomechanism which causes the probe to traverse an equipotential automatically. A stepping relay operated by a limit switch effects automatic plotting of successive equipotentials and limits the plot to a desired area. A number of plots made with such an apparatus are reproduced.
Chiral, Enantiopure Aluminum(<scp>III</scp>) and Titanium(<scp>IV</scp>) Azatranes (2006)

Abstract Al III and Ti IV complexes of C 3 ‐symmetric tetradentate trisamidoamine ligands with trigonal bipyramidal coordination geometry, containing chlorine or dialkylamido groups, or with a free coordination site in the apical position, have been synthesised by salt metathesis and amine elimination. Products with threefold symmetry were generally obtained for tetravalent titanium, whereas for the aluminium complexes either asymmetric structures with two of the three podand arms taking part in coordination to the metal or symmetric arrangements possessing the full threefold symmetry were formed depending on the steric properties of the ligands. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)
Colloidal gold probes--a further evaluation. (1979)

Colloidal gold provides an immuno- and cytochemical marker suitable both for TEM and SEM. Various parameters involved in the preparation and stability of gold markers of various sizes and of probes have been reviewed and modifications in methodology suggested based on a study of factors affecting the performance of the gold marker system. In particular, dependence of protein adsorption on pH conditions correlating with protein pI is further confirmed. Presence of bioactive protein in gold probes is demonstrated and quantitated by radioassay (125I) and agglutination procedures.
High Performance Electrically Conductive Silicone Adhesives (1990)

Silicones have long been recognised as attractive materials for use in electronics applications because of their unique combination of properties. Now, technology which couples high electrical conductivity with silicone performance characteristics has been developed. The new silver-filled silicone adhesives were processed and cured in a manner similar to that used in conventional heat cured silicone compositions. Resultant cured products were both highly flexible and highly conductive, exhibiting volume resistivities down to 2 × 10−4 ohm-cm. Both flexibility and electrical conductivity were retained after extended periods at elevated temperature. The electrical performance obtained while the new adhesives were under strain (induced either mechanically or thermally) was attributed to changes in the spatial packing of the silver. Low temperature characterisation indicated that the materials remain soft and stress-relieving even down to −60°C. Other physical characteristics of these compositions, such as high ionic purity, low moisture uptake and good adhesion, are typical of high performance electrically conductive adhesives. This combination of properties suggests that these new silicone adhesives should be attractive for the electrical interconnection of microelectronics substrates having a mismatch of thermal coefficients of expansion (TCE) which would normally lead to failure due to thermomechanical stresses, and for the manufacture of flexible circuitry.
Inhibition of Monoamine Oxidases by Functionalized Coumarin Derivatives:  Biological Activities, QSARs, and 3D-QSARs (2000)

A large series of coumarin derivatives (71 compounds) were tested for their monoamine oxidase A and B (MAO-A and MAO-B) inhibitory activity. Most of the compounds acted preferentially on MAO-B with IC(50) values in the micromolar to low-nanomolar range; high inhibitory activities toward MAO-A were also measured for sulfonic acid esters. The most active compound was 7-[(3, 4-difluorobenzyl)oxy]-3,4-dimethylcoumarin, with an IC(50) value toward MAO-B of 1.14 nM. A QSAR study of 7-X-benzyloxy meta-substituted 3,4-dimethylcoumarin derivatives acting on MAO-B yielded good statistical results (q(2)() = 0.72, r(2)() = 0.86), revealing the importance of lipophilic interactions in modulating the inhibition and excluding any dependence on electronic properties. CoMFA was performed on two data sets of MAO-A and MAO-B inhibitors. The GOLPE procedure, with variable selection criteria, was applied to improve the predictivity of the models and to facilitate the graphical interpretation of results.
Automatic Classifier Fusion for Produce Recognition (2012)

Recognizing different kinds of fruits and vegetables is a common task in supermarkets. This task, however, poses several challenges as it requires the identification of different species of a particular produce and also its variety. Usually, existing computer-based recognition approaches are not automatic and demand long-term and laborious prior training sessions. This paper presents a novel framework for classifier fusion aiming at supporting the automatic recognition of fruits and vegetables in a supermarket environment. The objective is to provide an effective mechanism for combining low-cost classifiers trained for specific classes of interest. The experiments performed demonstrate that the proposed framework yields better results than several related work found in the literature and represents a step forward automatic produce recognition in cashiers of supermarkets.
Production of drop-in fuels from biomass at high selectivity by combined microbial and electrochemical conversion (2017)

Joining the forces of reactor microbiomes and electrochemistry: production of drop-in fuels from complex biomass and electrical energy.
Partial freezing as a means of preserving fish freshness. I. Changes in free amino acids, TMA-N, ATP and its related compounds, and nucleic acids during storage. (1974)

In order to develop a storage procedure to be used in place of iced or frozen storage for the preservation of fish freshness, partial freezing for periods of up to 2-3 weeks was examined using sea bass. The criteria for evaluation were made according to the changes in the amounts of free amino acids and trimethylamine nitrogen as well as post-mortem autodegradation of nucleotides and nucleic acids in fish muscle.The changes in the free amino acids of muscle during storage at -3°C differed significantly from those observed during ice storage, though no significant differences were observed between the muscles iced and stored at -2°C. During storage at -3°C, no appreciable amount of trimethylamine nitrogen was detected, initial spoilage of the fish being greatly reduced. The K value of fish muscle stored at -3°C reached 20% after 2 weeks, whereas that of iced muscle reached 58% in 5 days.The possibility that nucleic acids in fish muscle might be broken down to their mononucleotide constituents during ice storage or storage at -3°C was almost negligible as far as could be determined colorimetrically with the phloroglucinol reaction. However, degradation of nucleic acid molecules in iced muscle was indicated by the results of chromatography on methylated albumin kieselgur, whereas the degradation was reduced noticeably in muscle stored at -3°C.From the present results with sea bass, storage by partial freezing at -3°C seems to be effective as a means of preserving fish freshness when storage must be prolonged beyond the storage life of iced fish.
Spectroelectrochemical Study of <i>N</i>‐Substituted Phenoxazines as Electrochemical Labels of Biomolecules (2006)

Abstract The electrochemical conversion of N ‐substituted phenoxazines (NSP's) bearing a CH 2 CH 2 X substitute (where XOH, COOH, CH 2 NH 2 , CH 2 SO 3 H, CH 2 NHCOR) was investigated using cyclic voltammetry on a bulk gold electrode and a thin‐layer spectroelectrochemical cell. The electrochemical oxidation of NSP's on the gold electrode was quasi‐reversible and proceeded in a diffusion‐controlled regime. The formal redox potential of NSP's covered the range from 0.39 to 0.45 V vs. SCE. The electrochemical oxidation of NSP's in the thin‐layer spectroelectrochemical cell produced radical cations that showed absorbance at 385, 410 and 530 nm. Electrochemical conversion fitted the general voltammetric current‐potential equation of a reversible wave, whereas electrolysis at constant potential showed a typical Cottrell behavior. Combining of NSP's with a biologically‐relevant theophylline molecule did not change electrochemical and spectral properties of the phenoxazine core. Theophylline enlarged with NSP's demonstrated electrochemical and biocatalytic behavior similar to that of NSP's. The investigated NSP's possess electrochemical and spectral properties that are useful as biomolecular labels for electroanalysis.