gebhart/patrepeval huggingface dataset:
Digital simulation of fault location on EHV lines using wideband spread spectrum techniques (1995)

Spread spectrum techniques perform well in high-noise environments such as power lines, and their use in radar ranging is well known. Existing power line carrier (PLC) equipment may be used to transmit a direct sequence signal down a faulted EHV line. The fault position may then be calculated from correlation analysis of the reflected waveforms. This fault-location process has been simulated on a digital computer by taking into account the frequency variation of the PLC interface and line parameters over the spread spectrum bandwidth. The effect of waveform characteristics and fault location are examined for a 100 km double transposed line with a single phase to ground fault. Results indicate that permanent faults may be located to within 0.5 km.
Synthese von substituierten Oxazolidonen‐(2) (1960)

Abstract Epoxyde lagern sich an Isocyanate zu substituierten Oxazolidonen‐(2) an. Anstelle der Epoxyde lassen sich auch die cyclischen Carbonate und Sulfite von 1.2‐Diolen verwenden.
Influence of humidity on current waveform and light emission of a low-frequency discharge controlled by a dielectric barrier (1996)

The aim of this work is to determine the effect of humidity on a silent discharge in air. A point to plane configuration has been used. Current and emission spectra of the discharge have been recorded in dry and humid air for short and long inter-electrode gaps and with the plane electrode coated by a silicone rubber plate alone or under a polypropylene film. Results show the typical corona discharge regimes. For a long gap, humidity decreases the number of breakdown streamer pulses. For a short gap, the behavior observed depends on the surface conduction of the dielectric in contact with the discharge. These results show that the presence of humidity in the discharge cell not only modifies the gas but also the surface states of the dielectrics coating the electrodes. The surface charge decay appears as a major parameter, since it is related to the local field value which results from the applied field and the reverse field induced by charge accumulation during previous discharges.
Enhanced inhibition of tissue factor by the extended form of an endothelial cell glycoprotein (an extrinsic pathway inhibitor) (1991)

We have identified, in the supernatant medium of cultured endothelial cells, an additional inhibitor of tissue factor that is eluted at higher salt concentrations during heparin-Sepharose chromatography and is a much more potent inhibitor of the activation of the coagulation cascade than the species we studied earlier (Colburn and Buonassisi: In Vitro Cellular and Developmental Biology 24: 1133-1136, 1988). The inhibitor we described earlier has been shown to be functionally and immunologically identical to a rabbit plasma extrinsic pathway inhibitor, EPI (Warn-Cramer et al.: Thrombosis Research 61:515-527, 1991). The new species (molecular mass, 47 kDa) is susceptible to proteolytic cleavage which results in a sharp reduction of its ability to inhibit tissue factor and an increase in electrophoretic mobility compatible with a molecular mass of 45 kDa, the same as that of the inhibitor reported earlier. Based on these data, we suggest that the new inhibitor yields, through proteolytic cleavage of an amino acid sequence of about 25 residues, the N-glycan-sulfated compound previously described.
Use of the DNA sequence of variable regions of the 16S rRNA gene for rapid and accurate identification of bacteria in the<i>Lactobacillus acidophilus</i>complex (2000)

The Lactobacillus acidophilus complex includes Lact. acidophilus, Lactobacillus amylovorus, Lactobacillus crispatus, Lactobacillus gallinarum, Lactobacillus gasseri and Lactobacillus johnsonii. The objective of this work was to develop a rapid and definitive DNA sequence-based identification system for unknown isolates of the Lact. acidophilus complex. A approximately = 500 bp region of the 16S rRNA gene, which contained the V1 and V2 variable regions, was amplified from the isolates by the polymerase chain reaction. The sequence of this region of the 16S rRNA gene from the type strains of the Lact. acidophilus complex was sufficiently variable to allow for clear differentiation amongst each of the strains. As an initial step in the characterization of potentially probiotic strains, this technique was successfully used to identify a variety of unknown human intestinal isolates. The approach described here represents a rapid and definitive method for the identification of Lact. acidophilus complex members.
Lead zirconate titanate thin films for microwave device applications (1998)

The preparation of sol–gel derived thin films of the piezoelectric ceramic lead zirconate titanate (PZT) has been investigated on different substrate configurations for bulk acoustic wave device applications operating at microwave frequencies. Films having a composition of Pb(Zr0.53Ti0.47)O3 have been prepared on platinised silicon (Pt–Si) and platinised gallium arsenide (Pt–GaAs) substrates using a 1,3-propanediol and a novel 1,1,1-tris(hydroxymethyl)ethane based sol–gel technique. Crystalline PZT films were produced on the Pt–GaAs by firing the sol–gel coating at 650°C for a dwell time of 1 second using rapid thermal processing techniques. A single deposition of the precursor sol resulted in films having a thickness of ~0.4 µm. Average values of remanent polarisation for the films were 29 and 24 µC/cm2 on Pt–Si and Pt–GaAs, respectively. Microwave characterisation performed on PZT/Pt–Si based BAW resonator structures indicate a fundamental parallel resonance at 0.1 GHz, having an unloaded QF of 1 × 1011 Hz.
Representing rock: Poetry and popular music (1994)

(1994). Representing rock: Poetry and popular music. Popular Music and Society: Vol. 18, No. 2, pp. 1-12.
Foam Mobility Control for Nanoparticle-Stabilized CO2 Foam (2012)

Abstract For miscible displacement under most reservoir conditions, due to the very low viscosity of the CO2 phase, poor volumetric sweep efficiency is a critical weakness of CO2 enhanced oil recovery (EOR). In this paper, a dynamic process for generating nanoparticle-stabilized CO2 foam is presented, which is expected to reduce CO2 mobility during CO2 EOR. This paper also describes the factors of nanoparticle concentration, CO2/brine volumetric ratio, and total injection rate effects on dynamic CO2 foam generation and foam mobility. Dynamic supercritical CO2 foam was generated by the shearing of supercritical CO2 and nanoparticle dispersions in a glass- bead packed column. The foam image was observed in an online sapphire tube. Particle size was determined to be in the range of 60–90 nm. The experimental results showed that stable dynamic foam was generated at a shear rate higher than 1419s‒1 at 1500 psig and 25°C. The pressure differentials along the glass bead packed column and capillary tube were used to characterize the CO2 foam mobility and the corresponding apparent foam viscosity. It was found that the yield shear rate increased from 1419s‒1 to 3312s‒1 as the injection rate increased from 3.0ml/min to 7.0ml/min, and the apparent foam viscosity with nanoparticle dispersion was 1.5 to 2.5 times higher than that without the dispersion. The corresponding mobility was nine times higher. With increasing nanoparticle concentration, the normalized mixture viscosity increased and related mobility decreased. Furthermore, the apparent viscosity decreased slightly as the CO2/brine ratio was varied from 2 to 11 at the constant flow rate of 6ml/min.
Valsartan for Prevention of Recurrent Atrial Fibrillation (2009)

Treatment with valsartan was not associated with a reduction in the incidence of recurrent atrial fibrillation. (ClinicalTrials.gov number, NCT00376272.)
Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing (2007)

Advances in immune assessment, including the development of T-cell receptor excision circle (TREC) assays of thymopoiesis, cytokine-flow cytometry assays of T-cell function, and higher-order phenotyping of T-cell maturation subsets have improved our understanding of T-cell homeostasis. Limited data exist using these methods to characterize immune recovery in adult cord blood (CB) transplant recipients, in whom infection is a leading cause of mortality. We now report the results of a single-center prospective study of T-cell immune recovery after cord blood transplantation (CBT) in a predominantly adult population. Our primary findings include the following: (1) Prolonged T lymphopenia and compensatory expansion of B and natural killer (NK) cells was evident; (2) CB transplant recipients had impaired functional recovery, although we did observe posttransplantation de novo T-cell responses to cytomegalovirus (CMV) in a subset of patients; (3) Thymopoietic failure characterized post-CBT immune reconstitution, in marked contrast to results in other transplant recipients; and (4) Thymopoietic failure was associated with late memory T-cell skewing. Our data suggest that efforts to improve outcomes in adult CB transplant recipients should be aimed at optimizing T-cell immune recovery. Strategies that improve the engraftment of lymphoid precursors, protect the thymus during pretransplant conditioning, and/or augment the recovery of thymopoiesis may improve outcomes after CBT.
Fundamental and Innovations in Plasma Assisted Diffusion of Nitrogen and Carbon in Austenitic Stainless Steels and Related Alloys (2009)

Abstract An improvement of the surface properties of austenitic stainless steels and nickel‐based alloys is obtained by low temperature plasma assisted nitriding (PAN), plasma assisted carburizing (PAC) and plasma assisted nitrocarburizing (PANC). At low temperature, PAN treatment produces a peculiar phase usually called expanded austenite, S phase, m phase or γ N phase. Replacing nitrogen by hydrocarbon for conducting a low temperature PAC gives a carburized layer containing the carbon expanded austenite phase ( γ C ). These two phases can simultaneously be obtained by combining hydrocarbon and nitrogen in the gas phase through a low temperature PANC. Several fundamental aspects concerning the expanded austenite phases are presented in this paper. magnified image
Linear rotation-invariant coordinates for meshes (2005)

We introduce a rigid motion invariant mesh representation based on discrete forms defined on the mesh. The reconstruction of mesh geometry from this representation requires solving two sparse linear systems that arise from the discrete forms: the first system defines the relationship between local frames on the mesh, and the second encodes the position of the vertices via the local frames. The reconstructed geometry is unique up to a rigid transformation of the mesh. We define surface editing operations by placing user-defined constraints on the local frames and the vertex positions. These constraints are incorporated in the two linear reconstruction systems, and their solution produces a deformed surface geometry that preserves the local differential properties in the least-squares sense. Linear combination of shapes expressed with our representation enables linear shape interpolation that correctly handles rotations. We demonstrate the effectiveness of the new representation with various detail-preserving editing operators and shape morphing.
Addicted to sugar: roles of glycans in the order<i>Mononegavirales</i> (2018)

Glycosylation is a biologically important protein modification process by which a carbohydrate chain is enzymatically added to a protein at a specific amino acid residue. This process plays roles in many cellular functions, including intracellular trafficking, cell-cell signaling, protein folding and receptor binding. While glycosylation is a common host cell process, it is utilized by many pathogens as well. Protein glycosylation is widely employed by viruses for both host invasion and evasion of host immune responses. Thus better understanding of viral glycosylation functions has potential applications for improved antiviral therapeutic and vaccine development. Here, we summarize our current knowledge on the broad biological functions of glycans for the Mononegavirales, an order of enveloped negative-sense single-stranded RNA viruses of high medical importance that includes Ebola, rabies, measles and Nipah viruses. We discuss glycobiological findings by genera in alphabetical order within each of eight Mononegavirales families, namely, the bornaviruses, filoviruses, mymonaviruses, nyamiviruses, paramyxoviruses, pneumoviruses, rhabdoviruses and sunviruses.
Can QRS scoring predict left ventricular scar and clinical outcomes? (2013)

QRS scoring performed best in quantifying transmural scar, and shows association with medium-term mortality risk, but not with risk of ventricular arrhythmia. It may be that the score is best suited as a risk stratifier of those with least potential to benefit from ICD.
Krylov Subspace Methods on Supercomputers (1989)

This paper presents a short survey of recent research on Krylov subspace methods with emphasis on implementation on vector and parallel computers. Conjugate gradient methods have proven very useful on traditional scalar computers, and their popularity is likely to increase as three-dimensional models gain importance. A conservative approach to derive effective iterative techniques for supercomputers has been to find efficient parallel/vector implementations of the standard algorithms. The main source of difficulty in the incomplete factorization preconditionings is in the solution of the triangular systems at each step. A few approaches consisting of implementing efficient forward and backward triangular solutions are described in detail. Then polynomial preconditioning as an alternative to standard incomplete factorization techniques is discussed. Another efficient approach is to reorder the equations so as to improve the structure of the matrix to achieve better parallelism or vectorization. An overview of these ideas and others is given in this article, as well as an attempt to comment on their effectiveness or potential for different types of architectures.
Efficient High-Performance ASIC Implementation of JPEG-LS Encoder (2007)

This paper introduces an innovative design which implements a high-performance JPEG-LS encoder. The encoding process follows the principles of the JPEG-LS lossless mode. The proposed implementation consists of an efficient pipelined JPEG-LS encoder, which operates at a significantly higher encoding rate than any other JPEG-LS hardware or software implementation while keeping area small
The heterogeneity of nerve growth factor receptors. (1979)

Chick embryonic sensory ganglia cells have two specific nerve growth factor receptors, site I and site II receptors, whose binding affinities differ by two orders of magnitude. As judged by both steady state binding and kinetic data, the two receptors behave independently. The rate of dissociation of the labeled nerve growth factor from site I receptors is increased in the presence of unlabeled nerve growth factor even when its concentration is below that of the labeled growth factor used to equilibrate the cells, a phenomenon which cannot be explained by negative cooperativity. Site I receptors are present only on neurons while site II receptors are present on both neurons and nonneuronal cells. At the concentration of nerve growth factor which produces half maximal stimulation of neurite outgrowth 8% of site I and 0.1% of site II receptors are occupied. This occupancy of site II receptors falls to about 0.01% with bisdesarginine beta nerve growth factor, a derivative which is as biologically active as the unmodified factor but which binds with lower affinity to site II receptors. These data support the idea that interaction of nerve growth factor with site I receptors is responsible for the initiation of neurite outgrowth.
Cloning, characterization and developmental expression of α2,8 sialyltransferase (GD3 synthase, ST8Sia I) gene in chick brain and retina (1997)

GD3 and GM2 synthases act on ganglioside GM3 at the branching point of the pathway of synthesis of gangliosides in which the "a", "b" and "c" families are produced. The relative activities of these enzymes are important for regulating the ganglioside composition of a given tissue. In the present work, we report the cloning and characterization of a chick GD3 synthase cDNA. The cloned cDNA directed the synthesis of a functionally active enzyme in transiently transfected CHO-K1 cells and was highly homologous to mammalian GD3 synthases. In Northern blot experiments the cDNA detected a single specific GD3 synthase mRNA of about 9.0 kb both in the chicken brain and retina. The abundance of the specific mRNA transcript declined steadily from E7-E9 to very low values around PN2. The levels of enzyme activities measured at the same developmental stages roughly followed the changes of specific mRNA levels in both tissues. In situ hybridization of embryonic neural retina cells in culture showed that both glial- and neuron-like cells expressed the specific GD3 synthase mRNA, although with different intensities. Results indicate that transcription and/or stability of the specific GD3 synthase mRNA constitute a level of control of the expression of GD3 synthase and indirectly of the ganglioside composition in the developing chicken central nervous system (CNS).
Kinetic study of the lipase-catalyzed interesterification of triolein and stearic acid in nonpolar media (1997)

The kinetics of the interesterification of triolein and stearic acid catalyzed by immobilized Rhizopus delemar lipase were studied in a batch operation. In order to clarify the mechanisms of this reaction, three models are discussed under various conditions in terms of the ratio of triolein and stearic acid. The rate constants involved in the proposed model were determined by combining the numerical Gauss-elemination method, and the trial-and-error method so as to fit the calculated results with the experimental data. The accuracy of the obtained rate constants was confirmed after they were substituted for simultaneous differential equations and the equations simulated using an adaptive step-size Runge-Kutta method. Finally, the model which agrees with the calculated results and the experimental data was selected.
C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. (2002)

Breast cancer resistance protein (BCRP) confers multidrug resistance to cancer cells against agents such as SN-38 (an active metabolite of irinotecan), mitoxantrone, and topotecan. Among 59 human tumor cell lines tested, 6 cell lines, A549, NCI-H460, KM-12, HT-29, OVCAR-5, and RPMI8226, showed high BCRP expression. BCRP cDNA was isolated from 11 cancer cell lines and three variant cDNAs [G34A substituting Met for Val-12 (V12M), C421A substituting Lys for Gln-141 (Q141K), and 944-949 deletion lacking Ala-315 and Thr-316 (delta315-6)] were identified. G34A and C421A variants were polymorphisms, and 944-949 deletion was a splicing variant. C421A BCRP-transfected PA317 cells showed markedly decreased protein expression and low-level drug resistance compared with wild-type BCRP-transfected cells when transfectants expressed similar levels of BCRP mRNA. G34A or 944-949-deleted BCRP-transfected PA317 cells showed similar or somewhat lower protein expression and drug resistance compared with wild-type BCRP-transfected cells. Of 124 healthy Japanese volunteers, 67 were wild-type, 48 were heterozygous, and 9 were homozygous for the C421A allele. These results suggest that some people possess the C421A polymorphic BCRP gene and express low amounts of Q141K BCRP. In addition to that, C376T polymorphism in exon 4 substituting stop codon for Gln-126 was found in 3 of the 124 general Japanese population. This C376T polymorphism may also have high impact because active BCRP protein will not be expressed from the C376T allele. Therefore, people with C376T and/or C421A polymorphisms may express low amounts of BCRP, and this low BCRP expression might result in hypersensitivity of normal cells to such anticancer drugs as irinotecan and mitoxantrone.
Bone-Marrow Transplantation in the Maroteaux–Lamy Syndrome (Mucopolysaccharidosis Type VI) (1984)

A 13-year-old girl with the severe form of the Maroteaux-Lamy syndrome (mucopolysaccharidosis Type VI, arylsulfatase B deficiency) has had successful reconstitution with bone marrow from her HLA-MLC-matched sister who had normal arylsulfatase B activity. Full engraftment has been present for 24 months. The following biochemical and clinical changes have occurred: arylsulfatase B activity in peripheral lymphocytes and granulocytes increased to normal levels, and the activity in serial liver-biopsy specimens increased from about 3 per cent of the mean normal level 43 days after transplantation to about 16 per cent at 600 days. Urinary excretion of acid mucopolysaccharide decreased. Ultrastructural evidence of accumulated dermatan sulfate was no longer detectable in bone-marrow cells; in peripheral-blood lymphocytes, granulocytes, or platelets; or in Ito cells of liver. Twenty-four months after engraftment, hepatosplenomegaly was substantially decreased and cardiopulmonary function was normal. Visual acuity and joint mobility were also improved. The patient returned to school and continued to perform well in academic studies. Thus, bone-marrow transplantation provided a source of enzymatically normal cells, which have altered the metabolic and clinical course of the disease.
SecPAL Formalization and Extensions (2009)

This report presents an updated formalization of standard SecPAL as well as possible extensions to the language, including IN/OUT-safety, guarded universal quantification, infinite policies and assertion providers, and hierarchical parameters.
Expertise Matching via Constraint-Based Optimization (2010)

Expertise matching, aiming to find the alignment between experts and queries, is a common problem in many real applications such as conference paper-reviewer assignment, product-reviewer alignment, and product-endorser matching. Most of existing methods for this problem usually find “relevant” experts for each query independently by using, e.g., an information retrieval method. However, in real-world systems, various domain-specific constraints must be considered. For example, to review a paper, it is desirable that there is at least one senior reviewer to guide the reviewing process. An important question is: “Can we design a framework to efficiently find the optimal solution for expertise matching under various constraints?” This paper explores such an approach by formulating the expertise matching problem in a constraint based optimization framework. Interestingly, the problem can be linked to a convex cost flow problem, which guarantees an optimal solution under given constraints. We also present an online matching algorithm to support incorporating user feedbacks in real time. The proposed approach has been evaluated on two different genres of expertise matching problems. Experimental results validate the effectiveness of the proposed approach.
Further Studies toward the Stereocontrolled Synthesis of Silicon-Containing Peptide Mimics (2010)

Further studies are reported on the utilization of the versatile reaction between chiral sulfinimines and alkyldiphenylsilyl lithium reagents with the goal of preparing a wide range of silanediol-based protease inhibitors. In particular, focus has been placed to demonstrate how a number of genetically encoded amino acid side chains such as serine, threonine, tyrosine, lysine, proline, arginine, aspartate and asparagine might be incorporated into the overall approach. Efforts to apply this synthetic methodology for accessing biologically relevant silanediol dipeptide mimics are also described. This includes the synthesis of a potential inhibitor of the human neutrophil elastase, as well as a diphenylsilane mimic of a hexapeptide fragment of the human islet amyloid polypeptide.