gebhart/patrepeval huggingface dataset:
Simultaneous WDM signal detection realized by ultrafast field sampling (2009)

This paper proposes a novel detection technique for wavelength-division multiplexing (WDM) signals that uses the ultrafast field sampling approach. The proposed technique simultaneously samples the total field of the WDM signal with no wavelength-demultiplexing; its electrical post-processing provides a filtering function in the digital domain. As a result, the individual fields of the WDM channels, including mutual phase relationship, can be jointly reconstructed. As a preliminary demonstration, the simultaneous monitoring of a WDM signal composed of two channels with independent polarization states, is successfully performed using a dual-channel field sampling system with polarization diversity. This demonstration can be expanded to the detection of a WDM signal with N-channels by using an N-channel field sampling system. It is also experimentally-verified that the reconstructed fields preserve the mutual phase relationship of the original fields. This 'field sensitive' WDM detection may open new possibilities for advanced WDM monitoring systems and even the electrical compensation of linear and/or non-linear inter-channel cross-talk in digital coherent detection systems.
Fiber to polymer-waveguide coupling with low insertion loss (2015)

Low-loss coupling of optical fiber to a polymer waveguide was demonstrated using a V-groove on a silicon substrate. The waveguide was fabricated directly on the silicon substrate using a direct writing technique. The fiber was mounted in a V-groove on a SiO2-coated silicon substrate, and then the azo polymer was coated onto the substrate and cured at 200 °C. Finally a waveguide was ‘written’ precisely aligned with the fiber’s output tip. The insertion loss was measured to be about 1.1 dB.
Quantitative phase‐amplitude microscopy I: optical microscopy (2002)

In this paper, the application of a new optical microscopy method (quantitative phase-amplitude microscopy) to biological imaging is explored, and the issue of resolution and image quality is examined. The paper begins by presenting a theoretical analysis of the method using the optical transfer function formalism of Streibl (1985). The effect of coherence on the formation of the phase image is explored, and it is shown that the resolution of the method is not compromised over that of a conventional bright-field image. It is shown that the signal-to-noise ratio of the phase recovery, however, does depend on the degree of coherence in the illumination. Streibl (1985) notes that partially coherent image formation is a non-linear process because of the intermingling of amplitude and phase information. The work presented here shows that the quantitative phase-amplitude microscopy method acts to linearize the image formation process, and that the phase and amplitude information is properly described using a transfer function analysis. The theoretical conclusions are tested experimentally using an optical microscope and the theoretical deductions are confirmed. Samples for microscopy influence both the phase and amplitude of the light wave and it is demonstrated that the new phase recovery method can separate the amplitude and phase information, something not possible using traditional phase microscopy. In the case of a coherent wave, knowledge of the phase and amplitude constitutes complete information that can be used to emulate other forms of microscopy. This capacity is demonstrated by recovering the phase of a sample and using the data to emulate a differential interference contrast image.
3-(1<i>H</i>-Indazol-3-ylmethyl)-1,5-benzodiazepines:  CCK-A Agonists That Demonstrate Oral Activity as Satiety Agents (1996)

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXT3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A Agonists That Demonstrate Oral Activity as Satiety AgentsBrad R. Henke, Timothy M. Willson, Elizabeth E. Sugg, Dallas K. Croom, Robert W. Dougherty,, Kennedy L. Queen, Larry S. Birkemo, Gregory N. Ervin, Mary K. Grizzle, Michael F. Johnson, and Michael K. JamesView Author Information Glaxo Wellcome Research and Development, Five Moore Drive, Research Triangle Park, North Carolina 27709 Cite this: J. Med. Chem. 1996, 39, 14, 2655–2658Publication Date (Web):July 5, 1996Publication History Received29 March 1996Published online5 July 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jm960249khttps://doi.org/10.1021/jm960249krapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views293Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Agonists,Food,Receptors,Rodent models,Selectivity Get e-Alerts
Mobile user interfaces for efficient verification of holograms (2015)

Paper documents such as passports, visas and banknotes are frequently checked by inspection of security elements. In particular, view-dependent elements such as holograms are interesting, but the expertise of individuals performing the task varies greatly. Augmented Reality systems can provide all relevant information on standard mobile devices. Hologram verification still takes long and causes considerable load for the user. We aim to address this drawback by first presenting a work flow for recording and automatic matching of hologram patches. Several user interfaces for hologram verification are presented, aiming to noticeably reduce verification time. We evaluate the most promising interfaces in a user study with prototype applications running on off-the-shelf hardware. Our results indicate that there is a significant difference in capture time between interfaces but that users do not prefer the fastest interface.
A Protein Kinase Activity Is Associated with and Specifically Phosphorylates the Neural Cell Adhesion Molecule LI (1989)

The neural cell adhesion molecule L1 is a phosphorylated integral membrane glycoprotein that is recovered from adult mouse brain by immunoaffinity chromatography as a set of polypeptides with apparent molecular masses of 200, 180, 140, 80, and 50 kilodaltons (L1-200, L1-180, L1-140, L1-80, and L1-50, respectively). In the present study, we show that two kinase activities are associated with immunopurified L1: One specifically phosphorylates L1-200 and L1-80 but not L1-180, L1-140, or L1-50. This pattern of phosphorylation corresponds to the one described for L1 after metabolic phosphate incorporation into cultures of cerebellar cells. In both cases, serine is the main amino acid that is labeled by radioactive phosphate. The kinase activity is not activated by Ca2+, calmodulin, phosphatidylserine, diolein, cyclic AMP, or cyclic GMP, a result suggesting that the enzyme is distinct from Ca2+/calmodulin-dependent kinases, from protein kinase C, or from cyclic AMP/cyclic GMP-dependent kinases and may belong to the independent kinase group. The other kinase phosphorylates only casein but not L1, utilizes GTP as well as ATP, and is strongly inhibited by heparin. Because the primary structure of the L1 protein does not contain consensus sequences characteristic for known kinases, we believe that the catalytic activities detectable in immunopurified L1 are due to kinases that are strongly enough associated with L1 to withstand the stringent purification procedures.
Geospatial Information Data Classification and Coding Scheme (2010)

In order to achieve integrated organizing and managing massive heterogeneous geospatial information data that is cross-department, distributed, multi-source, multi-disciplinary, multi-temporal and multi-type, this paper adopted method of linear classification, design geo-feature classification system, and proposed a set of unified coding scheme based on feature type about geospatial information data, It was designed according to the characteristics and application requirements of our resources and environment and basic geospatial information resources, also with reference to research achievements and standards on classification and coding that have been accumulated over the years by the various departments, This scheme has a certain practicality, compatibility, stability, systematic and integrity. It provides support for our sharing of geographic information.
Plasma 25-Hydroxyvitamin D Levels and Risk of Incident Hypertension (2007)

Hydroxylation of 25(OH)D to 1,25-dihydroxyvitamin D and signaling through the vitamin D receptor occur in various tissues not traditionally involved in calcium homeostasis. Laboratory studies indicate that 1,25-dihydroxyvitamin D suppresses renin expression and vascular smooth muscle cell proliferation; clinical studies demonstrate an inverse association between ultraviolet radiation, a surrogate marker for vitamin D synthesis, and blood pressure. We prospectively studied the independent association between measured plasma 25-hydroxyvitamin D [25(OH)D] levels and risk of incident hypertension and also the association between predicted plasma 25(OH)D levels and risk of incident hypertension. Two prospective cohort studies including 613 men from the Health Professionals' Follow-Up Study and 1198 women from the Nurses' Health Study with measured 25(OH)D levels were followed for 4 to 8 years. In addition, 2 prospective cohort studies including 38 388 men and 77 531 women with predicted 25(OH)D levels were followed for 16 to 18 years. During 4 years of follow-up, the multivariable relative risk of incident hypertension among men whose measured plasma 25(OH)D levels were <15 ng/mL (ie, vitamin D deficiency) compared with those whose levels were >or=30 ng/mL was 6.13 (95% confidence interval [CI]: 1.00 to 37.8). Among women, the same comparison yielded a relative risk of 2.67 (95% CI: 1.05 to 6.79). The pooled relative risk combining men and women with measured 25(OH)D levels using the random-effects model was 3.18 (95% CI: 1.39 to 7.29). Using predicted 25(OH)D levels in the larger cohorts, the multivariable relative risks comparing the lowest to highest deciles were 2.31 (95% CI: 2.03 to 2.63) in men and 1.57 (95% CI: 1.44 to 1.72) in women. Plasma 25(OH)D levels are inversely associated with risk of incident hypertension.
EphA4 is localized in clathrin‐coated and synaptic vesicles in adult mouse brain (2010)

EphA4, a receptor tyrosine kinase, is expressed in various pre-, post- and peri-synaptic organelles and implicated in the regulation of morphological and physiological properties of synapses. It regulates synaptic plasticity by acting as a binding partner for glial ephrin-A3 and possibly other pre- or post-synaptic ephrins. Now, its trafficking mechanisms remain unknown. In this study, we examine the association of EphA4 with transport, clathrin-coated and synaptic vesicles using cell fractionation, vesicle immunoisolation and electron microscopy. EphA4 was found in highly purified fractions of clathrin-coated or synaptic vesicles. It was also detected in vesicles immuno-isolated with antibodies anti-synaptophysin, anti-vesicular glutamate transporter or anti-vesicular GABA transporter; demonstrating its presence in synaptic vesicles. However, it was not detected in immuno-isolated piccolo-bassoon transport vesicles. In vivo and in dissociated cultures, EphA4 was localized by immunoelectron microscopy in vesicular glutamate transporter 1-positive terminals of hippocampal neurons. Remarkably, the cell surface immunofluorescence of EphA4 increased markedly in cultured hippocampal neurons following KCl depolarization. These observations indicate that EphA4 is present in subsets of synaptic vesicles, can be externalized during depolarization, and internalized within clathrin-coated vesicles. This trafficking itinerary may serve to regulate the levels of EphA4 in the synaptic plasma membrane and thereby modulate signaling events that contribute to synaptic plasticity.
Hereditary Chronic Conjugated Hyperbilirubinemia in Mutant Rats Caused by Defective Hepatic Anion Transport (1985)

A mutant rat strain is described with autosomal recessive conjugated hyperbilirubinemia. Transport of conjugated bilirubin and tetrabromosulfophthalein from liver to bile is severely impaired whereas uptake of organic anions from plasma to liver is normal. During the first 10 days of life, serum bilirubin levels are 147 +/- 11 mumoles per liter with 68.7% diconjugates and 27.9% monoconjugates. In adult rats, serum bilirubin is 33 +/- 8 mumoles per liter with 81.8% diconjugates and 12.1% monoconjugates vs. 0.3 +/- 0.1 mumole per liter unconjugated bilirubin in normal adult rats. Bile acid metabolism is only mildly affected. In young rats, serum bile acid levels are normal. In adult rats, bile acid levels are elevated to 49 +/- 11 mumoles per liter vs. 10 +/- 6 mumoles per liter in normal rats. The bile flow in mutant rats is reduced to about 50%. This might be caused by a reduction of the bile acid-independent bile fraction. Liver marker enzyme activities in mutant rat serum are normal. Liver morphology is also normal. Total urinary coproporphyrin excretion is not elevated but urinary coproporphyrin isomer I excretion is increased, a pattern like that in Dubin-Johnson syndrome in humans. However, unlike Dubin-Johnson syndrome, the mutant rats do not have the characteristic black hepatic pigment. These rats provide a unique model to study mechanisms of bile formation and cholestasis.
当代新马克思主义代表人物简介——罗歇·伽罗迪 (1988)

罗歇·伽罗迪1913年生于马赛,曾就学巴黎大学文学院,获哲学博士学位.在其学术生涯中,先后在阿尔比大学(阿尔及尔)、巴黎比丰公立中学(1958—1959)、克莱蒙费朗大学(1962—1965)与普瓦蒂埃大学(1965、1969—1973)任教,获得过苏联科学院哲学研究所名誉博士称号。伽罗迪在政治上也很活跃,作为塔尔纳地区的代表,两次入选国民议会(1945—1946),并被选为第一届全国国会议员(1946—1951)。他是法国共产党政治局委员,共产党的国会议员、国会副主席,并当选为参议院的共产党议员(1959—1962)。他是马克思主义学习和研究中心的指导人(1960—1970)。1974年以后,任法国激进杂志《社会主义的种种选择》编辑部主任。
Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas(lpr) mice from early lethality (1997)

MRL/MpJ-Fas(lpr) (Fas(lpr)) mice develop a rapidly fatal form of systemic autoimmune disease characterized by glomerulonephritis and vasculitis similar to severe cases of systemic lupus erythematosus in humans. To evaluate the requirement for intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of tissue injury in this model, we created ICAM-1-deficient MRL/MpJ-Fas(lpr) (ICAM-1/Fas(lpr)) mice. ICAM-1 deficiency resulted in a striking improvement in the survival of Fas(lpr) mice (median +/- SEM survival of Fas(lpr) = 26 +/- 1.7 vs ICAM-1/Fas(lpr) = 47 +/- 2.4 wk, p < 0.0001) and the increased survival was associated with delayed elevations of blood urea nitrogen levels in the ICAM-1/Fas(lpr) mice. Histologic examination of the ICAM-1/Fas(lpr) mice revealed an overall reduction in glomerular disease and a significant reduction in vasculitis in the kidney, lung, skin, and salivary glands when compared with Fas(lpr). These findings indicate that ICAM-1 plays a major role in development of glomerular and vascular injury in Fas(lpr) mice.
St. John's wort has no effect on pain in polyneuropathy (2001)

Tricyclic antidepressants are the mainstay of treatment of painful polyneuropathy but cannot be used in a substantial number of patients. St. John's wort is a herbal antidepressant, which may act via mechanisms similar to the tricyclics. The aim of this study was to test if St. John's wort would relieve painful polyneuropathy. The study design was randomized, double-blind, placebo-controlled and cross-over. Fifty-four patients were assigned to one of the two treatment sequences. The daily dose of St. John's wort was three tablets each containing 900 microg totalhypericin. During the two treatment periods of 5 weeks duration, patients rated constant pain, lancinating pain paroxysms, touch-evoked pain and pain on pressure by use of 0--10 point numeric rating scales. Forty-seven patients -- 18 diabetics and 29 non-diabetics -- completed the study. There was a trend of lower total pain score (sum of the individual pain scores) on St. John's wort than on placebo (median 14 vs. 15, P=0.05). None of the individual pain ratings were significantly changed by St. John's wort as compared to placebo (P=0.09--0.33). Complete, good or moderate pain relief was experienced by nine patients with St. John's wort and two with placebo (P=0.07). In conclusion, St. John's wort has no significant effect on pain in polyneuropathy.
Brief Communications (1979)

The Lending Division of the British Library continues to assemble at Boston Spa as comprehensive a collection as possible of the world's worthwhile serial literature in all languages and subject fields. Its current holdings are listed in its annual directory Current Serials Received. For the last few years there has been a remarkably uniform net increase of 4% in the number of titles received, and in August 1978 the total exceeded 50,000 for the first time. The graph (Figure 1) shows how the collection of current serials has grown over the years. The relatively steep parts of the curve around 1967 and 1972 are the result of a broadening of the library's scope to include firstly social science and secondly humanities. 37% of the titles come from just two countries — the USA (20.3%) and GB (16.8%). Only two other countries, Germany (8.3%) and the USSR (6.4%), are responsible for more than 5%. The complete breakdown is shown in the following table.
New architectures for low-power delta-sigma analog-to-digital converter (2008)

Two recently developed architectures, both applying an internal coupling of the quantization noise, are described. They allow higher-order noise shaping with high linearity and robust performance. Implemented examples of the proposed structures are described to verify their effectiveness.
Unique Diketopiperazine Dimers from the Insect Pathogenic Fungus <i>Verticillium hemipterigenum</i> BCC 1449 (2005)

[structure: see text]. Vertihemiptellides A (1) and B (2), unique diketopiperazine dimers, were isolated from the insect pathogenic fungus Verticillium hemipterigenum BCC 1449. Structures of these compounds were elucidated by NMR and mass spectral analysis, and the stereochemistry of 1 was determined by X-ray crystallography. The absolute stereochemistry of bisdethiodi(methylthio)-1-demethylhyalodendrin (3), previously isolated from the same fungus, was revised to the (3R,6R) configuration.
MERPL: A more memory-efficient storing mode in RPL (2013)

The IPv6 Routing Protocol for Low-power and Lossy Networks (RPL) allows a node to operate in storing or non-storing mode. However, as the network size increases, non-storing RPL will introduce lots of communication overhead, while storing RPL will consume lots of memory. In this paper, we improve the storing mode in RPL by reducing the memory consumption. Our performance studies show that our scheme effectively reduces communication overhead compared with the pure non-storing mode. In addition, it makes sure that the number of routing table entry stored in a node does not exceed a pre-specified factor N. When a node stores N routing table entries, it still has enough memory to run the node program and store the collected sensor data. Even when the size of network is large, nodes near the root can still provide adequate space to store the routing table entries using our scheme, but in pure storing mode they may not.
Adsorption of Pb(II) from an Aqueous Solution by Titanium Dioxide/Carbon Nanotube Nanocomposites: Kinetics, Thermodynamics, and Isotherms (2010)

In the present study, titanium dioxide/multiwalled carbon nanotubes (TiO2/MWCNTs) nanocomposites have been synthesized, characterized, and used for the adsorption of Pb(II) from aqueous solution. The pH effect, kinetics, adsorption isotherms, and thermodynamics are examined in batch experiments. The time dependence of Pb(II) adsorption onto TiO2/MWCNTs and MWCNTs nanocomposites can be described by a pseudosecond-order kinetic model. The Langmuir isotherm model agrees well with the equilibrium experimental data. The maximum adsorption capacity of TiO2/MWCNTs and MWCNTs nanocomposites has been found to be (137.0 and 33.0) mg·g−1, respectively. Various thermodynamic parameters such as the Gibbs energy (ΔG°), enthalpy (ΔH°), and entropy (ΔS°) changes are calculated. Our results have shown that TiO2/MWCNTs nanocomposites can be used as an effective adsorbent for Pb(II) due to the high adsorption capacity as well as the short adsorption time needed to achieve equilibrium.
Cloning and sequencing of E. coli trxA gene (1997)

The encoding region of trxA gene was amplified by PCR from E.coli genomic DNA and cloned into plasmid pUC19. The nucleotide sequence of the target DNA was determined by the dideoxy chain termination method with forward and reverse primers. The nucleotide sequence was consisted with the known gene except one base.
Relationship between microemulsion phase behavior and macroemulsion type in systems containing nonionic surfactant (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRelationship between microemulsion phase behavior and macroemulsion type in systems containing nonionic surfactantB. P. BinksCite this: Langmuir 1993, 9, 1, 25–28Publication Date (Print):January 1, 1993Publication History Published online1 May 2002Published inissue 1 January 1993https://pubs.acs.org/doi/10.1021/la00025a008https://doi.org/10.1021/la00025a008research-articleACS PublicationsRequest reuse permissionsArticle Views915Altmetric-Citations85LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts