gebhart/patrepeval huggingface dataset:
Quantitative Determination of Antibody in Idiopathic Thrombocytopenic Purpura (1975)

We studied the clinical applicability of a recently developed technic that determines antiplatelet antibody directly on the platelet surface or in serum. The technic is a quantitative complement lysis-inhibition assay. Normal platelets have less than 0.4 pg of surface IgG. All patients with idiopathic thrombocytopenic purpura who were studied had greater than that value. Surface IgG was increased in inverse proportion to the platelet count. Surface levels of greater than 1.1 pg correlated with failure to respond to prednisone therapy. Incubation of normal serums with normal platelets did not increase surface IgG of such platelets, but their incubation with thrombocytopenic serums increased their surface IgG 0.5 to 100 times. The degree of increase did not predict response to treatment. However, quantitation of surface IgG of thrombocytopenic platelets was useful in predicting response to treatment. (N Engl J Med 292:230–236,1975)
Novel highly nonlinear memristive circuit elements for neural networks (2012)

Highly nonlinear dynamics arises from novel serially and antiserially connected memristive switches. Antiserially connected memristors offer a device with built-in spiking neuron behavior. Serially connected memristors offer new functionality of a cascade of sigmoid staircase curves to represent multi-level spike-timing dependent plasticity (STDP). In a programming operation, a serial arrangement of two switches displays multiple time-delays between threshold transitions showing three distinct current levels and an arrangement of three switches four current levels spanning 6 orders of magnitude. Anti-serially connected resistive switches, aka resistive floating electrode device (RFED), can generate well-controlled spikes as a result of the history of the dynamic input. Both types of composite switches can be packed into a single intersection of a memristive crossbar architecture of 4F <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The switches have been manufactured as a multi-stack of Cu, TaO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> , Pt materials with 32 nm of oxygen-deficient TaO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> in a crossbar architecture.
Chaotic oscillators and complex mapping feed forward networks (CMFFNs) for signal detection in noisy environments (2003)

The use of chaotic systems for signal processing applications is limited by the ability to understand and interpret oscillator output results. Currently, phase plane data are used for system study, but neural networks are particularly well suited for this application. The authors have developed a complex-mapping-feedforward-network (CMFFN) that can interpret the phase plane data from chaotic systems. It is shown that this network, in conjunction with a chaotic oscillator, is able to distinguish signals buried in random Gaussian noise. The CMFFN is capable of detecting a signal with a 12-dB signal-to-noise ratio.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Disease Caused by a Marine Vibrio (1979)

We studied the clinical characteristics and epidemiology of disease associated with a rare, unnamed halophilic lactose-fermenting Vibrio species in 39 persons from whom the organism had been isolated. Two distinct clinical presentations were seen. In the first, the illness began with septicemia, often within 24 hours after raw oysters had been eaten; 18 of 24 such patients had pre-existing hepatic disease, and 11 of the 24 died. In the second, there was a wound infection after exposure to seawater or an injury incurred during the handling of crabs; none of these persons had pre-existing hepatic disease, and one of 15 died. Most cases (85 per cent) occurred during relatively warm months (May to October) in men (90 per cent) 40 or more years of age (95 per cent). This Vibrio species is a pathogen and should be considered in the differential diagnosis of septicemia with secondary skin lesions and of wound infections after exposure to seawater.
A Software Tool for Floating Point Interval Analysis with Improved Precision for Javascript-Based Medical Applications (2016)

Medical applications intimately rely on floating point numbers to store, retrieve and process important physical as well as diagnostic data associated with medical clients. The occurrence of unexpected loss of precision over floating point numbers under medical contexts can cause great damage, or even cost lives. Due to its excellent interoperability with web-based content, Javascript has been an important source language to craft mission-critical medical applications utilizing the web-based capabilities. For those applications, applying javascript static program analysis is an important counter measure against runtime errors including floating point number errors. In this paper, we propose an abstract interpretation based interval analysis for Javascript programs using floating point bounds. We base our method and results on top JSAI, a Javascript static analysis framework.
Fluxless no-clean assembly of solder bumped flip chips (2002)

MCNC has developed a radically new fluxless, no-clean process which has shown considerable success with assembly of a variety of flip chip configurations. The process, called PADS (Plasma Assisted Fluxless Soldering) relies on a pretreatment which enables the subsequent solder reflow in inert ambients. Conventional mass production soldering tools can be used, just eliminating the flux dispense and flux cleaning steps, and adding the pretreatment step. Highlights of the applications studies are presented. Examples include high lead (97Pb3Sn) bumped flip chips joined to multilayer ceramic substrates with Mo/Mi/Au microsockets at 350/spl deg/C in nitrogen, eutectic tin/lead solder bumped flip chips joined at 250/spl deg/C to bare copper, 95/5 lead/tin bumped flip chips joined to eutectic dipped FR4 printed circuit boards, joining of 90/10 lead tin bumps to each other at 350/spl deg/C, unique MEMS (Micro Electrical Mechanical Systems) devices joined with the dry fluxless process, and solder bumped flip chips joined to flexible circuits. Other related topics to be discussed include tacking, self alignment and its measurement, balling reflow, and rework operations including hot chip pull and site dress. Other areas of application of the fluxless process are highlighted including hermetic seal band attachment, joining of flexible circuit TAB leads to insulator substrates, and joining to solid solder deposits on FR4.
Functional group-containing copolymers prepared by Ziegler-Natta process (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFunctional group-containing copolymers prepared by Ziegler-Natta processS. Ramakrishnan, E. Berluche, and T. C. ChungCite this: Macromolecules 1990, 23, 2, 378–382Publication Date (Print):January 1, 1990Publication History Published online1 May 2002Published inissue 1 January 1990https://pubs.acs.org/doi/10.1021/ma00204a004https://doi.org/10.1021/ma00204a004research-articleACS PublicationsRequest reuse permissionsArticle Views492Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fast Link Adaptation for MIMO OFDM (2010)

We investigate link-quality metrics (LQMs) based on raw bit-error-rate, effective signal-to-interference-plus-noise ratio, and mutual information (MI) for the purpose of fast link adaptation (LA) in communication systems employing orthogonal frequency-division multiplexing and multiple-input-multiple-output (MIMO) antenna technology. From these LQMs, the packet error rate (PER) can be estimated and exploited to select the modulation and coding scheme (MCS) among a class of candidate MCSs that achieves the maximum throughput for the current channel state under a specified target PER objective. We propose a novel MI-based LQM and compare the PER-estimation accuracy obtained with this LQM with that resulting from using other LQMs by means of comprehensive Monte Carlo simulations. Search methods for the MCS in the class that is most suitable for a given channel state are presented. An algorithm for obtaining a practical upper bound on the throughput of any LA scheme is proposed. The investigated LQMs are applied to the IEEE 802.11n standard with a 2 × 2 MIMO configuration and practical channel estimation. The proposed MI-based LQM yields the highest PER estimation accuracy, and its throughput shows only 1.7 dB signal-to-noise-ratio (SNR) loss with respect to the upper bound but up to 9.5 dB SNR gain, compared to the MCS maximizing the throughput for the current noise variance.
Spectrophotometric Determination of Sulfur Dioxide Using <i>p</i>-Aminoazobenzene. (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrophotometric Determination of Sulfur Dioxide Using p-Aminoazobenzene.S. J. Kniseley and L. J. ThroopCite this: Anal. Chem. 1966, 38, 9, 1270–1271Publication Date (Print):August 1, 1966Publication History Published online1 May 2002Published inissue 1 August 1966https://doi.org/10.1021/ac60241a044RIGHTS & PERMISSIONSArticle Views80Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (250 KB) Get e-Alertsclose Get e-Alerts
Amplification and expression of the TGF-α, EGF receptor and c-<i>myc</i> genes in four human oesophageal squamous cell carcinoma lines (1993)

We have previously shown that four human oesophageal squamous cell carcinoma (SCC) cell lines secrete significant quantities of transforming growth factor alpha (TGF-alpha) in vitro. Three of these lines are known to produce supernumerary low-affinity epidermal growth factor receptors (EGF-Rs). Using an 125I-EGF competitive binding assay and Scatchard analysis, we show that the fourth also overproduces low-affinity receptors. According to slot blot DNA analyses, the secretion of high levels of TGF-alpha is not associated with amplification of the TGF-alpha gene, and hyperproduction of the EGF-R is correlated with receptor gene amplification. Western blot analyses show that the c-Myc protein is overexpressed in two of the cell lines; and Southern and Northern blot analyses indicate that this overexpression occurs independently of c-myc gene amplification. Our results are consistent with an autocrine role for TGF-alpha and EGF-R in oesophageal carcinogenesis and support the possibility that c-myc overexpression may be required for the in vivo tumourigenicity of cells that produce high levels of TGF-alpha and the EGF-R.
Fluoroaromatic Resists for 157-nm Lithography. (2002)

Lithography with 157-nm fluorine lasers is rapidly emerging as the next evolutionary step in optical lithography and is clearly seen as the likely successor to 193-nm lithography. As has been demonstrated with the transition to shorter wavelengths in the past, the resist materials that were developed for the longer wavelength applications are too absorbent for practical use as high-resolution single layer resist with 157-nm radiation. Fluorine containing polymers have been demonstrated to be more transparent in this spectral region than pure hydrocarbon polymers. We have developed and evaluated a number of unique fluoroaromatic-based 157-nm resists including 4-hexafluoroisopropanol styrene copolymers with t-butyl acrylate and acetyl blocked 4-hexafluoroisopropanol styrene. Our recent resist designs are shown to have imaging capability down to 70nm with a 0.60 NA microstepper.
Adversarial Information Retrieval Aspects of Sponsored Search. (2006)

Search engines are commercial entities that require revenue to survive. The most prevalent revenue stream for search engines is sponsored search, where content providers have search engines service their links to users in response to queries or in a contextual manner on relevant Web sites. In exchange for providing this service, content providers pay search engines based on the number of clicks (i.e., a click being a visit by a user to the content providers Web page). This business model has proven to be very effective for the search engines, content providers, and searchers. However, click fraud, a unique form of adversarial information retrieval, threatens this business model and, therefore, the &quot;free search&quot; that has rapidly become indispensable to the daily lives of many people. In this paper, we outline how sponsored search is a unique form of information retrieval -- not just a mode of advertising, what is click fraud, how click fraud happens, and what are some possible countermeasures.
The Concept and Implementation of Data-Driven Processor Arrays (1987)

V arious topologies and architec-tural designs for processor arrays have recently been proposed. These designs include systolic arrays and globally asynchronous wavefront arrays. &apos; Both array types have a computation front that propagates according to a predeter-mined control sequence, and consequently these control-driven arrays have proven to be very effective for executing highly regu-lar algorithms like vector and matrix oper-ations. There are, however, many computationally demanding problems that do not exhibit high regularity and may therefore prove unsuitable for these control-driven arrays. Still, many ofthese problems have an inherent parallelism, and it should be possible to exploit this parallelism by means of processor arrays that can provide a high degree of pipelining. In Koren and Silberman,2 a new approach to array design was proposed-that of developing specialized array architectures that would be capable of executing any given algorithm. In this approach, the algorithm is first repre-sented in the form of a dataflow graph (DFG) and is then mapped onto the array. The processing elements (PEs) in the array execute the operations included in the cor-responding nodes (or subsets of nodes) of the DFG; regular interconnections ofthese PEs serve as edges of the graph. In general, when an arbitrary algorithm is executed on an array there is no regular propagation of computation fronts. Hence, to speed up the execution of arbi-trary algorithms, a more flexible array is needed. Such an array should make pos-sible the generation of new computation fronts and their cancellation at a later time
Interference cancelation schemes for uplink transmission in femtocells (2010)

We present techniques that solve the near-far problems in femtocell networks. When a co-channel configuration is used, a transmission in the macrocell may cause interference to a femtocell. We introduce methods to cancel the interference caused by the macrocell to a femtocell by using the highrate link between the macrocell base station (BS) and the femtocell BS. In such a way, the interference from macrocell transmitters is completely cancelled when uplink transmission is used in the femtocell. Therefore, the allocation of time slots for uplink/downlink in a femtocell can be done by trying only to minimize the interference that a femtocell terminal experiences during a downlink transmission.
Constructing a personal web map with anytime-control of Web robots (1999)

In this paper, we propose a PWM (Personal Web Map) which is a personal and small database of interesting Web pages to a user and develop a method to construct it under the user's control of multiple Web robots. Though general search engines with large databases like YaHoo, AltaVista, MetaCrawler are valid it is important that a user constructs a small, personal database of relevant Web pages to his/her interest like Bookmarks. For such a Web page database, we propose a PWM: a personal database of interesting Web pages to a user which he/she can control its construction. First a user gives keywords indicating his/her interest to a system, and it constructs a PWM concerned with the keywords. For building a useful PWM, it is necessary that a user can interrupt the construction of a PWM anytime and instruct a sub-field in which a PWM should be expanded more. For this function, we develop an anytime-control algorithm for multiple Web robots. A density distribution blackboard is used, and an uniform distributed PWM is built. Whenever a system is interrupted by a user it provides a valid PWM in terms of keeping search space wide, and indicates many alternatives on which he/she wants more information. From Web pages in a database, document vectors are generated and used to construct a 2D-map of a PWM by using self-organization maps. A user easily recognizes a PWM through the 2D-map, and gives instruction by clicking a node about which he/she wants more detail information. We made experiments by users and found out that our method outperformed breadth-first search for constructing a useful PWM. As results, a PWM system is considered as a promising approach to assist a user in gathering relevant information in the WWW.
Efficient analog performance macromodeling via sequential design space decomposition (2006)

This paper presents a sequential design space decomposition technique for efficient analog feasibility and performance macromodeling. The performance macromodel is composed of one feasibility classifier and a set of performance regression models. The algorithm sequentially decomposes the design space into smaller partitions. We use a heuristic to identify the regions of significance. Feasibility classifiers of high precision and recall are constructed with low modeling cost within these regions. The final feasibility model is essentially a set of feasibility classifiers, each of which is valid for a subspace of the design space. The performance regression models constructed with much lower training instances have higher accuracy compared to a previous approach.
Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: A possible role for NGF in the pathogenesis of diabetic neuropathy (1990)

Sympathetic and neural-crest derived sensory neurons consisting of unmyelinated and small myelinated fibers are known to be affected at an early stage in diabetes mellitus (DM). Since these peripheral neurons need nerve growth factor (NGF) for their development and maintenance of function in adulthood, changes in endogenous NGF levels could be of relevance for the pathogenesis of diabetic neuropathy (DNP). Using an improved two-site enzyme immunoassay for NGF, we have investigated whether endogenous NGF levels are altered in Sprague-Dawley rats with DM induced by a single injection of streptozotocin (STZ). STZ-treated rats are known to develop in many respects equivalents to neuropathic complications observed in human DM. We found in some sympathetically innervated target organs decreased NGF contents by maximally 56%: transiently in the iris 2 weeks and in the ventricle 12-24 weeks after DM induction and permanently in the submandibular gland already 3 days after DM induction. Several weeks after onset of DM, NGF content was increased by maximally 145-300% in most peripheral targets investigated, such as in iris, cardiac atrium and ventricle, spleen, prostate gland, and vas deferens. This is suggestive for an impaired NGF removal by NGF-sensitive neurons in diabetic rats. Moreover, NGF levels were decreased to minimally 42.6 +/- 4% of control in the NGF-transporting sciatic nerve. NGF levels began to decrease not before 3 weeks after DM induction and remained decreased with 54.0 +/- 5% of control even after 6 months duration of DM. About the same time (i.e., 2 weeks after induction of DM) NGF levels began to decrease in the superior cervical ganglion (where the sympathetic perikarya are located) to minimally 53.2 +/- 4% of control 12 weeks after DM induction. No altered NGF levels were observed during a 3-month duration of DM in the terminal ileum and sensory trigeminal ganglion. Since NGF exerts its neurotrophic action in the perikarya after its retrograde transport from the NGF-producing periphery, our results are consistent with the hypothesis that an alteration in NGF levels may play a role in the pathogenesis of DNP as far as sympathetic neurons are concerned. Thus, our results suggest that DM influences the production and/or transport of endogenous NGF and consequently, that a deprivation of this neurotrophic factor may account for some of the functional deficits known to occur in DNP, such as impaired catecholaminergic transmitter synthesis. This hypothesis possibly opens the way for new concepts in the therapy of DNP.
Solving the Maximum Weight Planar Subgraph Problem by Branch-and-Cut (1993)

In this paper we investigate the problem of identifying a planar subgraph of maximum weight of a given edge weighted graph. In the theoretical part of the paper, the polytope of all planar subgraphs of a graph G is defined and studied. All subgraphs of a graph G, which are subdivisions of K5 or K3,3, turn out to define facets of this polytope.\n\nWe also present computational experience with a branch-and-cut algorithm for the above problem. Our approach is based on an algorithm which searches for forbidden substructures in a graph that contains a subdivision of K5 or K3,3. These structures give us inequalities which are used as cutting planes.
Mouse sn-glycerol-3-phosphate dehydrogenase: molecular cloning and genetic mapping of a cDNA sequence. (1983)

The isozymes of glycerol-3-phosphate dehydrogenase (GPDH; sn-glycerol-3-phosphate:NAD+2-oxidoreductase, EC 1.1.1.8) in tissues of the mouse are coded for by two structural genes, Gdc-1 and Gdc-2, located on chromosomes 15 and 9, respectively. In order to investigate the expression of these genes, we isolated a GPDH cDNA clone from a mRNA preparation isolated from brown adipose tissue. The GPDH cDNA clone was identified by colony hybridization and hybrid selection of a mRNA that was translated in vitro to produce immunoprecipitable GPDH protein. In blot analysis, the GPDH cDNA hybridized to a single mRNA species that migrated at the position of 23S ribosomal RNA. This GPDH cDNA clone was mapped to the Gdc-1 locus by identification of a restriction enzyme polymorphism present in genomic DNA isolated from Gdc-1 congeneic lines of mice.