gebhart/patrepeval huggingface dataset:
Synthesis and optical properties of a new class of polyamides containing reactive diacetylene groups (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and optical properties of a new class of polyamides containing reactive diacetylene groupsH. W. Beckham and Michael F. RubnerCite this: Macromolecules 1989, 22, 5, 2130–2138Publication Date (Print):May 1, 1989Publication History Published online1 May 2002Published inissue 1 May 1989https://doi.org/10.1021/ma00195a022RIGHTS & PERMISSIONSArticle Views230Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
Ultrafast current imaging by Bayesian inversion (2018)

Spectroscopic measurements of current-voltage curves in scanning probe microscopy is the earliest and one of the most common methods for characterizing local energy-dependent electronic properties, providing insight into superconductive, semiconductor, and memristive behaviors. However, the quasistatic nature of these measurements renders them extremely slow. Here, we demonstrate a fundamentally new approach for dynamic spectroscopic current imaging via full information capture and Bayesian inference. This general-mode I-V method allows three orders of magnitude faster measurement rates than presently possible. The technique is demonstrated by acquiring I-V curves in ferroelectric nanocapacitors, yielding >100,000 I-V curves in <20 min. This allows detection of switching currents in the nanoscale capacitors, as well as determination of the dielectric constant. These experiments show the potential for the use of full information capture and Bayesian inference toward extracting physics from rapid I-V measurements, and can be used for transport measurements in both atomic force and scanning tunneling microscopy.
Toward efficient check-pointing and rollback under on-demand SBST in chip multi-processors (2015)

In-field on-line testing techniques have recently been proposed for permanent fault detection caused by wear-out/aging-related defects manifesting during the lifetime of a system. Selective Software-Based Self-Testing (SBST) is one such paradigm focusing primarily on the recently stressed functional units of a multicore system at a sub-core granularity, in an attempt to reduce the application performance penalty caused by periodically testing the entire system. In this work, we complement our O/S-enabled framework DeamonGuard for on-demand (selective) SBST to support fault recovery capabilities. Towards this goal, we propose an efficient check pointing and rollback recovery mechanism which, upon fault detection, can restore the system to the most recently valid correct state and resume the normal operation assuming disabling of the faulty core, thereby leading to a healthy (but degraded) system. The work in this paper concentrates on reducing the number of stored checkpoints required when testing at a sub-core granularity, and minimizing the recovery penalty of such framework. We evaluate and demonstrate the overhead of the proposed recovery mechanism, and our results indicate a practical reduction in the number of stored checkpoints as well as a significant improvement in recovery latency for the cases where the faults are correlated with the stressed units.
Fluorescent products of reaction between .ALPHA.-keto acids and 1,2-diamino-4,5-dimethoxybenzene. (1985)

The fluorescent products formed from α-keto acids and 1, 2-diamino-4, 5-dimethoxybenzene were shown to be the corresponding 3-substituted 6, 7-dimethoxy-2 (1H)-quinoxalinones. The fluorescence properties of the products are described ; they fluoresce most intensely at pH 6.0-8.0.
Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian Cells (2016)

One of the goals of synthetic biology is to develop programmable artificial gene networks that can transduce multiple endogenous molecular cues to precisely control cell behavior. Realizing this vision requires interfacing natural molecular inputs with synthetic components that generate functional molecular outputs. Interfacing synthetic circuits with endogenous mammalian transcription factors has been particularly difficult. Here, we describe a systematic approach that enables integration and transduction of multiple mammalian transcription factor inputs by a synthetic network. The approach is facilitated by a proportional amplifier sensor based on synergistic positive autoregulation. The circuits efficiently transduce endogenous transcription factor levels into RNAi, transcriptional transactivation, and site-specific recombination. They also enable AND logic between pairs of arbitrary transcription factors. The results establish a framework for developing synthetic gene networks that interface with cellular processes through transcriptional regulators.
Systemic Induction of Salicylic Acid Accumulation in Cucumber after Inoculation with <i>Pseudomonas syringae</i> pv <i>syringae</i> (1991)

Inoculation of one true leaf of cucumber (Cucumis sativus L.) plants with Pseudomonas syringae pathovar syringae results in the systemic appearance of salicylic acid in the phloem exudates from petioles above, below, and at the site of inoculation. Analysis of phloem exudates from the petioles of leaves 1 and 2 demonstrated that the earliest increases in salicylic acid occurred 8 hours after inoculation of leaf 1 in leaf 1 and 12 hours after inoculation of leaf 1 in leaf 2. Detaching leaf 1 at intervals after inoculation demonstrated that leaf 1 must remain attached for only 4 hours after inoculation to result in the systemic accumulation of salicylic acid. Because the levels of salicylic acid in phloem exudates from leaf 1 did not increase to detectable levels until at least 8 hours after inoculation with P. s. pathovar syringae, the induction of increased levels of salicylic acid throughout the plant are presumably the result of another chemical signal generated from leaf 1 within 4 hours after inoculation. Injection of salicylic acid into tissues at concentrations found in the exudates induced resistance to disease and increased peroxidase activity. Our results support a role for salicylic acid as an endogenous inducer of resistance, but our data also suggest that salicylic acid is not the primary systemic signal of induced resistance in cucumber.
Are serum concentrations of nitric oxide metabolites useful for predicting the clinical outcome of severe ulcerative colitis? (1995)

In the majority of patients with severe ulcerative colitis, circulating concentrations of NOX are increased at presentation and fall promptly during parenteral steroid therapy, irrespective of clinical outcome. However, in a small number of patients NOX concentrations do not fall during steroid treatment and such patients will probably require additional medical therapy or surgery.
The efficacy of bedside chest ultrasound: from accuracy to outcomes (2016)

For many respiratory physicians, point-of-care chest ultrasound is now an integral part of clinical practice. The diagnostic accuracy of ultrasound to detect abnormalities of the pleura, the lung parenchyma and the thoracic musculoskeletal system is well described. However, the efficacy of a test extends beyond just diagnostic accuracy. The true value of a test depends on the degree to which diagnostic accuracy efficacy influences decision-making efficacy, and the subsequent extent to which this impacts health outcome efficacy. We therefore reviewed the demonstrable levels of test efficacy for bedside ultrasound of the pleura, lung parenchyma and thoracic musculoskeletal system.For bedside ultrasound of the pleura, there is evidence supporting diagnostic accuracy efficacy, decision-making efficacy and health outcome efficacy, predominantly in guiding pleural interventions. For the lung parenchyma, chest ultrasound has an impact on diagnostic accuracy and decision-making for patients presenting with acute respiratory failure or breathlessness, but there are no data as yet on actual health outcomes. For ultrasound of the thoracic musculoskeletal system, there is robust evidence only for diagnostic accuracy efficacy.We therefore outline avenues to further validate bedside chest ultrasound beyond diagnostic accuracy, with an emphasis on confirming enhanced health outcomes.
A microfluidic biochip for complete blood cell counts at the point-of-care (2015)

Complete blood cell counts (CBCs) are one of the most commonly ordered and informative blood tests in hospitals. The results from a CBC, which typically include white blood cell (WBC) counts with differentials, red blood cell (RBC) counts, platelet counts and hemoglobin measurements, can have implications for the diagnosis and screening of hundreds of diseases and treatments. Bulky and expensive hematology analyzers are currently used as a gold standard for acquiring CBCs. For nearly all CBCs performed today, the patient must travel to either a hospital with a large laboratory or to a centralized lab testing facility. There is a tremendous need for an automated, portable point-of-care blood cell counter that could yield results in a matter of minutes from a drop of blood without any trained professionals to operate the instrument. We have developed microfluidic biochips capable of a partial CBC using only a drop of whole blood. Total leukocyte and their 3-part differential count are obtained from 10 μL of blood after on-chip lysing of the RBCs and counting of the leukocytes electrically using microfabricated platinum electrodes. For RBCs and platelets, 1 μL of whole blood is diluted with PBS on-chip and the cells are counted electrically. The total time for measurement is under 20 minutes. We demonstrate a high correlation of blood cell counts compared to results acquired with a commercial hematology analyzer. This technology could potentially have tremendous applications in hospitals at the bedside, private clinics, retail clinics and the developing world.
ChemInform Abstract: Catalytic Asymmetric Allylic Alkylation with a Novel P‐S Bidentate Ligand. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Periodic Acid and Periodates. II. The System Silver Oxide–Periodic Acid–Water at 35°C. (1951)

ADVERTISEMENT RETURN TO ISSUEArticleNEXTPeriodic Acid and Periodates. II. The System Silver Oxide–Periodic Acid–Water at 35°C.P. P. GyaniCite this: J. Phys. Chem. 1951, 55, 7, 1111–1119Publication Date (Print):July 1, 1951Publication History Published online1 May 2002Published inissue 1 July 1951https://pubs.acs.org/doi/10.1021/j150490a001https://doi.org/10.1021/j150490a001research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Increasing EMMPRIN and matriptase expression in hepatocellular carcinoma: tissue microarray analysis of immunohistochemical scores with clinicopathological parameters (2006)

Our findings demonstrate for the first time that EMMPRIN and matriptase are overexpressed in HCC. These may be novel biomarkers for the diagnosis and treatment of HCC.
A Gold Standards Approach to Training Instructors to Evaluate Crew Performance (2003)

The Advanced Qualification Program requires that airlines evaluate crew performance in Line Oriented Simulation. For this evaluation to be meaningful, instructors must observe relevant crew behaviors and evaluate those behaviors consistently and accurately against established by the airline. The airline industry has largely settled on an approach in which instructors evaluate crew performance on a series of event sets, using standardized grade sheets on which behaviors specific to event set are listed. Typically, new instructors are given a class in which they learn to use the grade sheets and practice evaluating crew performance observed on videotapes. These classes emphasize reliability, providing detailed instruction and practice in scoring so that all instructors within a given class will give similar scores to similar performance. This approach has value but also has important limitations; (1) ratings within one class of new instructors may differ from those of other classes; (2) ratings may not be driven primarily by the specific behaviors on which the company wanted the crews to be scored; and (3) ratings may not be calibrated to company for level of performance skill required. In this paper we provide a method to extend the existing method of training instructors to address these three limitations. We call this method the gold standards approach because it uses ratings from the company's most experienced instructors as the basis for training rater accuracy. This approach ties the training to the specific behaviors on which the experienced instructors based their ratings.
Immunization with purified protein antigens from Streptococcus mutans against dental caries in rhesus monkeys (1981)

Protein antigens I, I/II, II, and III were prepared from Streptococcus mutans (serotype c). Their immunogenicities and protective effects against dental caries were investigated in 40 rhesus monkeys kept entirely on a human-type diet, containing about 15% sucrose. Antigens I, I/II and, to a lesser extent, antigen II induced significant reductions in dental caries, as compared with sham-immunized monkeys. This was achieved with 1 or 2 doses of antigen, the first of which was administered with adjuvant (Freund incomplete adjuvant or aluminum hydroxide). There was no reduction in caries in monkeys immunized with antigen III. The reduction in caries in the animals immunized with antigens I or I/II was comparable to that in monkeys immunized with whole cells. Protection against caries was associated predominantly with serum and gingival crevicular fluid immunoglobulin G antibodies, which appeared to be directed against the antigen I determinant, but antibodies to antigen II, though not to antigen III, were also protective.
Design Considerations for Supercritical Carbon Dioxide Brayton Cycles With Recompression (2014)

Supercritical carbon dioxide (SCO2) Brayton cycles have the potential to offer improved thermal-to-electric conversion efficiency for utility scale electricity production. These cycles have generated considerable interest in recent years because of this potential and are being considered for a range of applications, including nuclear and concentrating solar power (CSP). Two promising SCO2 power cycle variations are the simple Brayton cycle with recuperation and the recompression cycle. The models described in this paper are appropriate for the analysis and optimization of both cycle configurations under a range of design conditions. The recuperators in the cycle are modeled assuming a constant heat exchanger conductance value, which allows for computationally efficient optimization of the cycle's design parameters while accounting for the rapidly varying fluid properties of carbon dioxide near its critical point. Representing the recuperators using conductance, rather than effectiveness, allows for a more appropriate comparison among design-point conditions because a larger conductance typically corresponds more directly to a physically larger and higher capital cost heat exchanger. The model is used to explore the relationship between recuperator size and heat rejection temperature of the cycle, specifically in regard to maximizing thermal efficiency. The results presented in this paper are normalized by net power output and may be applied to cycles of any size. Under the design conditions considered for this analysis, results indicate that increasing the design high-side (compressor outlet) pressure does not always correspond to higher cycle thermal efficiency. Rather, there is an optimal compressor outlet pressure that is dependent on the recuperator size and operating temperatures of the cycle and is typically in the range of 30–35 MPa. Model results also indicate that the efficiency degradation associated with warmer heat rejection temperatures (e.g., in dry-cooled applications) are reduced by increasing the compressor inlet pressure. Because the optimal design of a cycle depends upon a number of application-specific variables, the model presented in this paper is available online and is envisioned as a building block for more complex and specific simulations.
Competing reactions in the peroxy-acid oxidation of 3-alkoxy-steroidal 3,5-dienes (1970)

D. N. Kirk and J. M. Wiles, J. Chem. Soc. D, 1970, 1015 DOI: 10.1039/C29700001015
Fabrication of silicon nanowire arrays by near-field laser ablation and metal-assisted chemical etching (2016)

We present an elegant route for the fabrication of ordered arrays of vertically-aligned silicon nanowires with tunable geometry at controlled locations on a silicon wafer. A monolayer of transparent microspheres convectively assembled onto a gold-coated silicon wafer acts as a microlens array. Irradiation with a single nanosecond laser pulse removes the gold beneath each focusing microsphere, leaving behind a hexagonal pattern of holes in the gold layer. Owing to the near-field effects, the diameter of the holes can be at least five times smaller than the laser wavelength. The patterned gold layer is used as catalyst in a metal-assisted chemical etching to produce an array of vertically-aligned silicon nanowires. This approach combines the advantages of direct laser writing with the benefits of parallel laser processing, yielding nanowire arrays with controlled geometry at predefined locations on the silicon surface. The fabricated VA-SiNW arrays can effectively transfect human cells with a plasmid encoding for green fluorescent protein.
Unified dispersion model for multilayer microstrip line (1992)

A unified dispersion model is presented to calculate frequency dependent dielectric constant for a multilayer microstrip line. The model is a combination of the transverse transmission line (TTL) method, the method for the reduction of multilayer structures to an equivalent single layer microstrip line, and the dispersion model of M. Kirschning and R.H. Jansen (1982). The result of the model has been confirmed within an accuracy of 1% against the results from SDA, ESDT, and MM, i.e., various forms of full wave analysis. These results have been confirmed between 2 GHz and 18 GHz. The present model is suitable for use in a CAD package for MIC, MMIC, and printed antenna design.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid (2002)

Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that is not only an effective solvent but also an active base catalyst.
Rapid detection of maintenance induced changes in service performance (2011)

Service quality in operational IP networks can be impacted due to planned or unplanned maintenance. During any maintenance activity, the responsibility of the operations team is to complete the work order and perform a check-up to ensure there are no unexpected service disruptions. Once the maintenance is complete, it is crucial to continuously monitor the network and look for any performance impacts. What operations lack today are effective tools to rapidly detect maintenance induced performance changes. The large scale and heterogeneity of network elements and performance metrics makes the problem extremely challenging.
Anthology of the renin-angiotensin system: a one hundred reference approach to angiotensin II antagonists. (1993)

This review raises the following questions for future research. (1) Will the long-term cardiovascular effects of angiotensin converting enzyme (ACE) inhibition, angiotensin II antagonism and renin inhibition be similar or not, and dependent or independent of blood pressure levels? (2) What are the local-regional interactions between vasoconstrictor and vasodilator systems, and does the renin-angiotensin system synchronize these regional hemodynamic regulatory mechanisms? (3) If hypertension is the result of an interaction between genetic and environmental factors, do proteins secreted through constitutive pathways contribute to the genetic abnormality (prorenin, angiotensinogen, ACE) while regulated secretion (renin) and other regulatory mechanisms (angiotensin II receptors) provide biological support for the environmental effects?
Sparse Array 3-D ISAR Imaging Based on Maximum Likelihood Estimation and CLEAN Technique (2010)

Large 2-D sparse array provides high angular resolution microwave images but artifacts are also induced by the high sidelobes of the beam pattern, thus, limiting its dynamic range. CLEAN technique has been used in the literature to extract strong scatterers for use in subsequent signal cancelation (artifacts removal). However, the performance of DFT parameters estimation based CLEAN algorithm for the estimation of the signal amplitudes is known to be poor, and this affects the signal cancelation. In this paper, DFT is used only to provide the initial estimates, and the maximum likelihood parameters estimation method with steepest descent implementation is then used to improve the precision of the calculated scatterers positions and amplitudes. Time domain information is also used to reduce the sidelobe levels. As a result, clear, artifact-free images could be obtained. The effects of multiple reflections and rotation speed estimation error are also discussed. The proposed method has been verified using numerical simulations and it has been shown to be effective.