gebhart/patrepeval huggingface dataset:
The PARSC trial, a prospective study for the assessment of recurrence risk in stage II colon cancer (CC) patients using ColoPrint. (2010)

TPS199 Background: Clinical trials have not yet shown if adjuvant chemotherapy is justified for stage II CC patients of whom 25% are at risk of recurrence. An 18-gene expression profile, ColoPrint, has been developed for identifying CC cancer patients more likely to develop recurrent disease and who would be candidates for adjuvant chemotherapy. The gene signature has been validated in independent cohorts of 440 CC patients. In one study (Glas et al, ASCO 2009), the profile classified 67% of the stage II patients (n=135) as low-risk. The HR for distant metastasis free survival (DMFS) was 3.27 (p=0.015) with a 5-year DMFS rate of 91% (95%CI 84-98) for low-risk and 72% (95%CI 58-88) for high-risk patients. Moreover, the profile stratified patients independent of ASCO clinical risk factors. Methods: A prospective trial, PARSC (Prospective study for the Assessment of Recurrence risk in Stage II CC patients using ColoPrint) has been initiated. The main objectives are: 1) Determine risk assessment by ColoPrint profile versus clinical parameters based on local protocol and ASCO high-risk recommendations in stage II patients. 2) Establish proportion of
DETERMINATION OF SINGLET OXYGEN RATE CONSTANTS IN AQUEOUS SOLUTIONS (1978)

Abstract— A very efficient quenching of singlet oxygen ( 1 O 2 ) by N 3 ‐ ions has been applied to the determination of rate constants of reactions of 1 O 2 with various substrates (A). This determination has been made possible by choosing experimental conditions which give simple competition between N 3 ‐ and A for 1 O 2 formed in the steady state irradiation of convenient sensitizing dye (S). The consumption of oxygen by the substrate, as followed with an oxygen analyzer, decreases in the presence of low concentrations of N 3 ‐ . Using neutral air saturated aqueous solutions containing the dye phenosafranine + A and varying concentrations of N 3 ‐ , the 1 O 2 rate constants for reactions with biological substrates and some radiation protective agents have been determined.
Mesenchymal Stem Cell Transplantation for Neurodegenerative Diseases (2008)

Neurodegenerative diseases are characterized by a progressive degeneration of selective neural populations. The lack of effective treatment and the characteristic of their pathology make these diseases appropriate candidates for cell therapy. Mesenchymal stem cells (MSCs) are multipotent stem-like cells that are capable of differentiating into mesenchymal and nonmesenchymal lineages. Their regenerative capacity after in vivo transplantation into animal models of neurodegenerative diseases has suggested that they could be useful against human diseases. Human bone marrow-derived MSCs (hMSCs) can be easily amplified in vitro and their transdifferentiation has been claimed in vitro and in vivo in neural cells. There are some doubts concerning the exact mechanisms responsible for the beneficial outcome observed after MSC transplantation into neurodegenerating tissues. Possible interpretations include cell replacement, trophic factor delivery, and immunomodulation. This review mainly concerns hMSCs transplantation in neurodegenerative diseases, because it has proven to be feasible, safe, and potentially effective. Although they have been used in hundreds of clinical trials, mixed results and no functional and long-lasting integration have so far been observed. hMSCs transplantations therefore still have their "dark side." However, the challenge in well-planned clinical trials merits discussion.
Elderly Patients with Advanced Non-Small Cell Lung Cancer: What Treatment? (2011)

Advanced non-small cell lung cancer (NSCLC) in elderly patients is an increasingly common problem which the practitioner of oncology must face.There is no consensus on the cut-off age for defining the elderly.However, 70 years may be the most appropriate because the incidence of age-related changes starts to increase after this boundary.Important concerns in evaluating the treatment of elderly patients are the presence of comorbidities and the progressive physiologic reduction of hepatic, renal and bone-marrow functions which could have a negative impact on the degree of toxicity.To individualize treatment choice within a group of elderly NSCLC patients of the same chronological age, it would be important to perform a comprehensive geriatric assessment (CGA) which would allow to subdivide elderly patients into three main categories: fit, pre-frail and frail.Fit older patients have similar prognosis and a similar treatment tolerance and outcome compared to their younger counterparts.On the other hand, pre-frail patients experience significant treatment related toxicity and usually are offered a single-agent chemotherapy whose choice should take into account the expected toxicity profile of the agent, pharmacokinetics, organ function and co-morbidities.For the third category of patients only best supportive care or individualized approaches are recommended.Overall, only prospective trials, specifically addressed to elderly NSCLC patients selected through an adequate CGA at baseline, let us opt for the best treatment to be administered to each elderly patient.
Achieving color uniformity across multi-projector displays (2000)

Large area tiled displays are gaining popularity for use in collaborative immersive virtual environments and scientific visualization. While recent work has addressed the issues of geometric registration, rendering architectures, and human interfaces, there has been relatively little work on photometric calibration in general, and photometric non-uniformity in particular. For example, as a result of differences in the photometric characteristics of projectors, the color and intensity of a large area display varies from place to place. Further, the imagery typically appears brighter at the regions of overlap between adjacent projectors. We analyze and classify the causes of photometric non-uniformity in a tiled display. We then propose a methodology for determining corrections designed to achieve uniformity, that can correct for the photometric variations across a tiled projector display in real time using per channel color look-up-tables (LUT).
Controlling the surface wettability of the polymer dielectric for improved resolution of inkjet-printed electrodes and patterned channel regions in low-voltage solution-processed organic thin film transistors (2014)

A facile method for realizing both inkjet printed electrodes with improved resolution and patterned semiconductor islands was developed to fabricate all solution processed low-voltage organic thin film transistors (OTFTs). By reducing the surface wettability of the polymer gate dielectric layer through coating of a self-assembled monolayer (SAM), fine and narrow inkjet printed source/drain electrodes (a line width of about 35 μm) and short channels (about 15 μm) were formed with very good yield and uniformity using an inkjet printer with a 10 pL drop volume print head and limited registration accuracy. The coated SAM layer was then selectively removed by ultraviolet ozone treatment to create patterned wettable and less wettable regions to form self-assembled organic semiconductor islands. The fabricated low voltage OTFTs present a high quality semiconductor/dielectric interface and good device performance.
Shift it to the server! Let the database server update your Web sites (2002)

From the beginnings of the World Wide Web, Web site administrators have used dynamically generated HTML pages to provide up-to-date information, e.g. online news, stock quotes, etc. Due to the high resource consumption of dynamic page generation approaches, many sites have switched over to periodical updates of frequently visited pages, e.g. a headline index of an electronic newspaper. However, this approach has led to reduced topicality of information. In this paper, we present iWebDB, an approach for automatic object-relational DBMS-controlled document updates. It offers up-to-date Web documents and, at the same time, avoids the drawbacks of dynamic page generation approaches. iWebDB is based on the extensibility infrastructure of object-relational database (DB) systems. By utilizing DB triggers and so-called user-defined functions, documents can be automatically generated by the DBMS whenever related DB data has been modified.
Effect of Boric Acid and BTCA on Tensile Strength Loss of Finished Cotton Fabrics (2004)

Several polycarboxylic acids have been studied as durable press finishing agents for cotton fabrics. The most effective is 1,2,3,4-butanetetracarboxylic acid (BTCA). One of the drawbacks of this crosslinking is the severe loss of mechanical strength of the treated fabrics, which is responsible for the reduced durability of finished cotton garments. In this research, boric acid mixed with BTCA is considered as a remedy for this problem. Fourier transform infrared spectra, tensile tests, and crease recovery angle (CRA) measurements are used to investigate the effects of the treatment. The results reveal that if cotton fabrics are treated with the combination of BTCA and boric acid, they show high CRA values at a low curing temperature. In the presence of sodium hypophosphite as a catalyst, higher CRA values may be obtained, although at higher curing temperatures. Interestingly, adding boric acid to BTCA in the right proportions leads to almost complete retention of the mechanical strength originally present in the untreated cotton.
[Expression of CCAAT/enhancer-binding protein in cultured rat hepatic stellate cells and its significance]. (2004)

C/EBPalpha was likely involved in the HSCs activation, and over-expressed C/EBPalpha by transfection had inhibitory influence on the proliferation of cultured rat HSCs.
A multi-level collaborative driving framework for autonomous vehicles (2009)

This paper proposes a multi-level collaborative driving framework (MCDF) for human-autonomous vehicle interaction. There are three components in MCDF; the mission-behavior-motion block diagram, the functionality-module relationship and the human participation level table. Through integration of the three components, a human driver can cooperate with the vehicle's intelligence to achieve better driving performance, robustness and safety. The MCDF is successfully implemented in TROCS, a real-time autonomous vehicle control system developed by the Tartan Racing Team for the 2007 DARPA Urban Challenge. The performance of MCDF is analyzed and a preliminary test in TROCS simulation mode shows that MCDF is effective in improving the driving performance.
Granular Flow: From Dilute to Jammed States (2017)

Particulate systems and granular matter display dynamic or static, fluid-or solid-like states, respectively, or both at the same time. The mystery of bridging the gap between the particulate, microscopic state and the macroscopic, continuum description is one of the challenges of modern research. This book chapter gives an overview of recent progress and some new insights about the collective mechanical behavior of granular, deformable particles.
Vibrio Parahaemolyticus and Related Halophilic Vibrios (1982)

Approximately 30 years have elapsed since Dr. Fujino's original discovery that Vibrio parahaemolyticus (then termed Pasteurella parahemolytica) was the cause of "summer diarrhea" in Japan. Since that finding, V. parahaemolyticus has been established as a cause of gastroenteritis in numbers and places approaching global proportions. It has been isolated in marine and estuarine areas almost worldwide and despite its halophilic nature, V. parahaemolyticus has been isolated from saline-free waters. The relationship of this organism to the environment reveals a close association with other marine organisms especially copepods on which the Vibrios depend for survival in winter months and growth in summer months. There is a uniquely provocative disparity between human strains of V. parahaemolyticus which are Kanagawa phenomenon (KP) positive and the environmental strains which to a large extent are KP negative, the significance being that pathogenicity is measured according to the Kanagawa phenomenon (hemolytic activity) reaction. The hemolysin of the pathogenic strains is a thermostable, cardiotoxic protein, which thus far has not been implicated in the mechanism(s) which causes human gastroenteritis. The interest in this organism has been widened in recent years by the finding that similar organisms, V. alginolyticus, lactose positive vibrios and group F vibrios also cause serious disease in humans.
How to Keep Track of Your Network Configuration (1993)

In this paper we present extensions for the Ined network editor allowing us to discover the structure of an IP network automatically. The discovering algorithm is based on an active probing technique that fits well with our interactive editor. We have chosen a multithreaded approach to minimize response times which seems reasonable in fast networks but may fail when run over slow serial links. A set of utilities have been designed to lay out the discovered network based on additional information found in the Domain Name System. Introduction Maps showing the network configuration are very important documents for a variety of tasks. This motivated us to design and implement a domain specific editor called Ined that is specialized for drawing and maintaining network maps [7]. Ined provides all necessary editing features to draw and maintain network maps. Maps may be composed of node, network and link objects. Link objects represent connections between two node objects or a node and a n...
Brain Natriuretic Peptide (2003)

eart failure is a nosological entity whose incidence is constantly rising, mostly due to the elevation of the population’s mean age. Diagnosis of heart failure is not an easy task, especially in the elderly, in women and in the obese, while particular diagnostic considerations arise for patients with dyspnea and edemas 2 . The prognosis of heart failure remains poor and its causes are not always clarified. For the aforementioned reasons, a simple, cheap and easily performed laboratory test, like the assessment of brain natriuretic peptide (BNP) plasma levels, that could help distinguish patients with heart failure from patients suffering from other causes of dyspnea when classical biochemical and imaging investigations fail to set the diagnosis, seems very appealing.
Review of applications of high-field asymmetric waveform ion mobility spectrometry (FAIMS) and differential mobility spectrometry (DMS) (2007)

High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) and Differential Mobility Spectrometry (DMS) harness differences in ion mobility in low and high electric fields to achieve a gas-phase separation of ions at atmospheric pressure. This separation is orthogonal to either chromatographic or mass spectrometric separation, thereby increasing the selectivity and specificity of analysis. The orthogonality of separation, which in some cases may obviate chromatographic separation, can be used to differentiate isomers, to reduce background, to resolve isobaric species, and to improve signal-to-noise ratios by selective ion transmission. This review will focus on the applications of these techniques to the separation of various classes of analytes, including chemical weapons, explosives, biologically active molecules, pharmaceuticals and pollutants. These papers cover the period up to January 2007.
Constant SOC control of a series Hybrid Electric Vehicle with long driving range (2010)

The efficiency improvement of Hybrid Electric Vehicle (HEV) is strongly dependent on the system-level control of the power flow in both the mechanical and the electrical paths of the vehicle. This is realized by the HEV control strategy. In this paper, a control strategy is proposed for a medium sized Series Hybrid Electric Vehicle (SHEV) designed for campus and gymnasium. The control strategy is composed of two parts: constant SOC control and driving range optimization. In constant SOC control, fuzzy logic is used to regulate the power flow and maintain the SOC of batteries always at a high level. Fuel economy and emissions are also considered by the controller. Both off-line and real-time simulations are performed and the results verify the design idea. In driving range optimization, Ant Colony Algorithm (ACA) is used to find the appropriate power sequence of Auxiliary Power Unit (APU). By comparing to thermostat control strategy, with the same fuel consumption the vehicle after optimization may have longer driving range.
X-ray determination of crystallinity and diffuse disorder scattering (1961)

An X-ray method of crystallinity determination has been developed which takes into account the diffuse scattering due to thermal vibrations and lattice imperfections in the crystalline part of a substance. Application of the method to a series of polypropylene samples shows that this diffuse scattering is predominantly caused by thermal motions.
Lanthanum(iii) catalysts for highly efficient and chemoselective transesterification (2013)

A facile, atom-economical, and chemoselective esterification is crucial in modern organic synthesis, particularly in the areas of pharmaceutical, polymer, and material science. However, a truly practical catalytic transesterification of carboxylic esters with various alcohols has not yet been well established, since, with many conventional catalysts, the substrates are limited to 1°- and cyclic 2°-alcohols. In sharp contrast, if we take advantage of the high catalytic activities of La(Oi-Pr)(3), La(OTf)(3), and La(NO(3))(3) as ligand-free catalysts, ligand-assisted or additive-enhanced lanthanum(III) catalysts can be highly effective acid-base combined catalysts in transesterification. A highly active dinuclear La(III) catalyst, which is prepared in situ from lanthanum(III) isopropoxide and 2-(2-methoxyethoxy)ethanol, is effective for the practical transesterification of methyl carboxylates, ethyl acetate, weakly reactive dimethyl carbonate, and much less-reactive methyl carbamates with 1°-, 2°-, and 3°-alcohols. As the second generation, nearly neutral "lanthanum(III) nitrate alkoxide", namely La(OR)(m)(NO(3))(3-m), has been developed. This catalyst is prepared in situ from inexpensive, stable, low-toxic lanthanum(III) nitrate hydrate and methyltrioctylphosphonium methyl carbonate, and is highly useful in the non-epimerized transesterification of α-substituted chiral carboxylic esters, even under azeotropic reflux conditions. In these practical La(III)-catalyzed transesterifications, colorless esters can be obtained in small- to large-scale synthesis without the need for inconvenient work-up or careful purification procedures.
How accurately can one reconstruct an index profile from transverse measurement data? (1985)

The question posed by the title is addressed by analyzing the size dependence of the reconstruction error <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">\deltan (\bar{r}) = n (\bar{r})_{reconst} - n (\bar{r})_{true}</tex> on the numerical aperture of the glass structure being profiled. This error is generated by means of computer simulation for two commonly used reconstruction methods. One method is accurate in the sense that it is based on rigorous ray theory and its use is shown to lead to only insignificant numerical errors. The second method is based on an approximate treatment of the ray equation and its application results in a systematic reconstruction error of magnitude <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n(R)\Delta^{2}/2</tex> . Hence, the latter method provides increasingly less accurate results as Δ increases. If one considers a reconstruction error of 1 part in 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> acceptable, then application of either method leads to satisfactory results in fiber-preform profiling work. However, care should be exercised in assessing the adequacy of a particular profile reconstruction method if it is to be used in profiling work on objects characterized by a larger numerical aperture than that typical of fiber preforms.
1.28 Tb/s single wavelength star-16-QAM transmission over up to 800 m of graded-index multimode fibre (2009)

For the first time, up to 160 Gbaud 16-QAM and 8-PSK transmission over graded-index multimode fibre is demonstrated using optical time division multiplexing and de-multiplexing in combination with coherent detection.
Transient behavior of a-Si(C):H bulk barrier color detectors (1998)

The photocurrent transient of a-Si(C):H n-i-p-i-n/p-i-n-i-p color detectors under pulse illumination at different wavelengths has been investigated. In contrast to amorphous silicon Schottky diodes and p-i-n/n-i-p structures, the photocurrent decay after the end of the steady state illumination is barely influenced by the applied bias voltage. Moreover, a reversal of the photocurrent direction can be observed under certain bias when the light is being switched on. It is suggested that these properties of n-i-p-i-n/p-i-n-i-p structures are mainly attributed to the accumulation and trapping of the photogenerated carriers near the central barrier.
Hollow ZnO Nanofibers Fabricated Using Electrospun Polymer Templates and Their Electronic Transport Properties (2009)

Thin (0.5 to 1 microm) layers of nonaligned or quasi-aligned hollow ZnO fibers were prepared by sputtering ZnO onto sacrificial templates comprising polyvinyl-acetate (PVAc) fibers deposited by electrospinning on silicon or alumina substrates. Subsequently, the ZnO/PVAc composite fibers were calcined to remove the organic components and crystallize the ZnO overlayer, resulting in hollow fibers comprising nanocrystalline ZnO shells with an average grain size of 23 nm. The inner diameter of the hollow fibers ranged between 100 and 400 nm and their wall thickness varied from 100 to 40 nm from top to bottom. The electronic transport and gas sensing properties were examined using DC conductivity and AC impedance spectroscopy measurements under exposure to residual concentrations (2-10 ppm) of NO(2) in air at elevated temperatures (200-400 degrees C). The inner and outer surface regions of the hollow ZnO fibers were depleted of mobile charge carriers, presumably due to electron localization at O(-) adions, constricting the current to flow through their less resistive cores. The overall impedance comprised interfacial and bulk contributions. Both contributions increased upon exposure to electronegative gases such as NO(2) but the bulk contribution was more sensitive than the interfacial one. The hollow ZnO fibers were much more sensitive compared to reference ZnO thin film specimens, displaying even larger sensitivity enhancement than the 2-fold increase in their surface to volume ratio. The quasi-aligned fibers were more sensitive than their nonaligned counterparts.