gebhart/patrepeval huggingface dataset:
High-Pressure Microfluidics (2013)

In this thesis, some fundamentals and possible applications of high-pressure microfluidics have been explored. Furthermore, handling fluids at high pressures has been addressed, specifically by creating and characterizing strong microvalves and pumps. A variety of microstructuring techniques was used to realize these microfluidic devices, e.g., etching, lithography, and bonding. To be able to handle high pressures, the valves and pumps need to be strong. This necessitates a strong actuator material. In this thesis, the material of choice is paraffin wax. A new way of latching paraffin-actuated microvalves into either closed or open position has been developed, using the low thermal conductivity of paraffin to create large thermal gradients within a microactuator. This allows for long open and closed times without power consumption. In addition, three types of paraffin-actuated pumps are presented: A peristaltic high-pressure pump with integrated temperature control, a microdispensing pump with high repeatability, and a pump system with two pumps working with an offset to reduce flow irregularities. Furthermore, the fundamental behavior of paraffin as a microactuator material has been explored by finite element modeling. One possibility that arises with high-pressure microfluidics, is the utilization of supercritical fluids for different applications. The unique combination of material properties found in supercritical fluids yields them interesting applications in, e.g., extraction and cleaning. In an attempt to understand the microfluidic behavior of supercritical carbon dioxide, the two-phase flow, with liquid water as the second phase, in a microchannel has been studied and mapped with respect to both flow regime and droplet behavior at a bi-furcating outlet.
Global burden of oral diseases: emerging concepts, management and interplay with systemic health (2015)

Oral disease remains a major public health burden worldwide. It is of great importance to integrate oral health into global health agenda via the common risk factor approach. The long-term sustainable strategy for global oral health should focus on health promotion and disease prevention through effective multidisciplinary teamwork.
I-JVM: a Java Virtual Machine for component isolation in OSGi (2009)

The OSGi framework is a Java-based, centralized, component oriented platform. It is being widely adopted as an execution environment for the development of extensible applications. However, current Java Virtual Machines are unable to isolate components from each other. For instance, a malicious component can freeze the complete platform by allocating too much memory or alter the behavior of other components by modifying shared variables. This paper presents I-JVM, a Java Virtual Machine that provides a lightweight approach to isolation while preserving compatibility with legacy OSGi applications. Our evaluation of I-JVM shows that it solves the 8 known OSGi vulnerabilities that are due to the Java Virtual Machine and that the overhead of I-JVM compared to the JVM on which it is based is below 20%.
Paenibacillus (Formerly Bacillus) gordonae (Pichinoty et. al. 1986) Ash et al. 1994 Is a Later Subjective Synonym of Paenibacillus (Formerly Bacillus) validus (Nakamura 1984) Ash et al. 1994: Emended Description of P. validus (1995)

A polyphasic study in which we performed an amplified ribosomal DNA restriction analysis, sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole-cell proteins, a gas chromatographic analysis of methylated fatty acids, pyrolysis mass spectrometry, a random amplified polymorphic DNA analysis, a phenotypic analysis, and an analysis of the levels of DNA binding of Paenibacillus gordonae and Paenibacillus validus strains (including both type strains) showed that these organisms form a homogeneous group and that the names P. gordonae and P. validus are therefore synonyms. P. validus has nomenclatural priority, and an emended description of this species is given; the type strain is strain LMG 11161 (= ATCC 43897).
Outcomes of Early- and Late-Identified Children at 3 Years of Age (2013)

Fifty-six percent of the 451 children were fitted with hearing aids before 6 months of age. At 3 years of age, 134 children used cochlear implants and the remaining children used hearing aids. On average, outcomes were well below population norms. Significant predictors of child outcomes include: presence/absence of additional disabilities, severity of hearing loss, gender, maternal education, together with age of switch-on for children with cochlear implants.
Changing authoritarian rule and public policy in Argentina, 1930-1970 (1991)

The study of changing authoritarian political systems, Luigi Manzetti setting the stage - political change and public policy the theoretical framework - authoritarianism, incrementalism, and constraints on decision makers who governed when in Agrentina - coalitions, presidents, cabinet officers, and public employees policies toward the state, the military, and society industrialization and foreign policies labour policies expenditure and revenue policies.
Degradation and absolute configurational assignment to C34-botryococcene (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDegradation and absolute configurational assignment to C34-botryococceneJames D. White, Todd C. Somers, and G. Nagabushana ReddyCite this: J. Org. Chem. 1992, 57, 18, 4991–4998Publication Date (Print):August 1, 1992Publication History Published online1 May 2002Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/jo00044a039https://doi.org/10.1021/jo00044a039research-articleACS PublicationsRequest reuse permissionsArticle Views1000Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Room-Temperature Epitaxial Growth of GaN on Atomically Flat MgAl<sub>2</sub>O<sub>4</sub> Substrates by Pulsed-Laser Deposition (2006)

We have grown GaN films on MgAl2O4(111) substrates at room temperature (RT) and investigated the structural properties of the films. The atomically flat surfaces of MgAl2O4 with a step and terrace structure are obtained by annealing at 1000 °C in a box made of ceramic MgAl2O4. It is found that GaN(0001) grows epitaxially on atomically flat MgAl2O4(111) surfaces even at RT. The epitaxial relationship between the GaN epilayer and the MgAl2O4 substrate is GaN[1120]∥MgAl2O4[011]. GaN films have a clear six fold symmetry without 30° rotational domains. The interfacial reaction between GaN and MgAl2O4 is completely suppressed in the case of RT growth.
The Induction of Amylase Synthesis in Barley Aleurone Layers by Gibberellic Acid (1972)

Journal Article The Induction of Amylase Synthesis in Barley Aleurone Layers by Gibberellic Acid: I. RESPONSE TO TEMPERATURE Get access P. B GOODWIN, P. B GOODWIN Research School of Biological Sciences, Australian National UniversityCanberra, A.C.T., Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar D. J. CARR D. J. CARR Research School of Biological Sciences, Australian National UniversityCanberra, A.C.T., Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Experimental Botany, Volume 23, Issue 1, February 1972, Pages 1–7, https://doi.org/10.1093/jxb/23.1.1-a Published: 01 February 1972 Article history Received: 20 April 1971 Published: 01 February 1972
Synthesis, structure and properties of thiophene-fused BODIPYs and azaBODIPYs as near-infrared agents (2016)

Annulation of thiophene to the BODIPY/aza-BODIPY core showed a significant impact on the spectral properties of the resulting scaffolds.
Oligonucleotide Syntheses on Insoluble Polymer Supports. I. Stepwise Synthesis of Trithymidine Diphosphate (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOligonucleotide Syntheses on Insoluble Polymer Supports. I. Stepwise Synthesis of Trithymidine DiphosphateL. Russell. Melby and Donald R. StrobachCite this: J. Am. Chem. Soc. 1967, 89, 2, 450–453Publication Date (Print):January 1, 1967Publication History Published online1 May 2002Published inissue 1 January 1967https://pubs.acs.org/doi/10.1021/ja00978a052https://doi.org/10.1021/ja00978a052research-articleACS PublicationsRequest reuse permissionsArticle Views154Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fast 6D pose estimation for texture-less objects from a single RGB image (2016)

A fundamental step to solve bin-picking and grasping problems is the accurate estimation of an object 3D pose. Such visual task usually rely on profusely textured objects: standard procedures such as detection of interest points or computation of appearance-based descriptors are favoured by using a highly informative surface. However, texture-less objects or their parts (i.e., those whose surface texture is poorly conditioned) are common in any environment but still challenging to deal with. This is due the fact that the distribution of surface brightness makes difficult to compute interest points or appearance-based descriptors. In this paper, we propose a method to estimate the 3D pose for texture-less objects given a coarse initialization: the pose is estimated using using edge correspondences, where the similarity measure is encoded using a pre-computed linear regression matrix. Furthermore, we also propose a method to increase the robustness of the estimated pose against background and object clutter. We validate both methods by using synthetic and real image sequences with objects with known ground truth.
Insulin‐Like Growth Factor (IGF) Binding Protein‐2, Independently of IGF‐1, Induces GLUT‐4 Translocation and Glucose Uptake in 3T3‐L1 Adipocytes (2017)

Insulin-like growth factor binding protein-2 (IGFBP-2) is the predominant IGF binding protein produced during adipogenesis and is known to increase the insulin-stimulated glucose uptake (GU) in myotubes. We investigated the IGFBP-2-induced changes in basal and insulin-stimulated GU in adipocytes and the underlying mechanisms. We further determined the role of insulin and IGF-1 receptors in mediating the IGFBP-2 and the impact of IGFBP-2 on the IGF-1-induced GU. Fully differentiated 3T3-L1 adipocytes were treated with IGFBP-2 in the presence and absence of insulin and IGF-1. Insulin, IGF-1, and IGFBP-2 induced a dose-dependent increase in GU. IGFBP-2 increased the insulin-induced GU after long-term incubation. The IGFBP-2-induced impact on GU was neither affected by insulin or IGF-1 receptor blockage nor by insulin receptor knockdown. IGFBP-2 significantly increased the phosphorylation of PI3K, Akt, AMPK, TBC1D1, and PKC<i>ζ</i>/<i>λ</i> and induced GLUT-4 translocation. Moreover, inhibition of PI3K and AMPK significantly reduced IGFBP-2-stimulated GU. In conclusion, IGFBP-2 stimulates GU in 3T3-L1 adipocytes through activation of PI3K/Akt, AMPK/TBC1D1, and PI3K/PKC<i>ζ</i>/<i>λ</i>/GLUT-4 signaling. The stimulatory effect of IGFBP-2 on GU is independent of its binding to IGF-1 and is possibly not mediated through the insulin or IGF-1 receptor. This study highlights the potential role of IGFBP-2 in glucose metabolism.
Magnetically Actuated Complementary Metal Oxide Semiconductor Resonant Cantilever Gas Sensor Systems (2005)

In the present paper, an electromagnetically actuated resonant cantilever gas sensor system is presented that features piezoresistive readout by means of stress-sensitive MOS transistors. The monolithic gas sensor system includes a polymer-coated resonant cantilever and the necessary oscillation feedback circuitry, both monolithically integrated on the same chip. The fully differential feedback circuit allows for operating the device in self-oscillation with the cantilever constituting the frequency-determining element of the feedback loop. The combination of magnetic actuation and transistor-based readout entails little power dissipation on the cantilever and reduces the temperature increase in the sensitive polymer layer to less than 1 degrees C, whereas previous designs with thermally actuated cantilevers showed a temperature increase of up to 19 degrees C. The lower temperature of the sensitive polymer layer on the cantilever directly improves the sensitivity of the sensor system as the extent of analyte physisorption decreases with increasing temperature. The electromagnetic sensor design shows an almost 2 times larger gas sensitivity than the earlier design, which is thermally actuated and read out using p-diffused resistors. The gas sensor is fabricated using an industrial complementary metal oxide semiconductor (CMOS) process and post-CMOS micromachining.
Photoacoustic Flow Cytometry for Single Sickle Cell Detection<i>In Vitro</i>and<i>In Vivo</i> (2016)

Control of sickle cell disease (SCD) stage and treatment efficiency are still time-consuming which makes well-timed prevention of SCD crisis difficult. We show here that <i>in vivo</i> photoacoustic (PA) flow cytometry (PAFC) has a potential for real-time monitoring of circulating sickled cells in mouse model. <i>In vivo</i> data were verified by <i>in vitro</i> PAFC and photothermal (PT) and PA spectral imaging of sickle red blood cells (sRBCs) expressing SCD-associated hemoglobin (HbS) compared to normal red blood cells (nRBCs). We discovered that PT and PA signal amplitudes from sRBCs in linear mode were 2-4-fold lower than those from nRBCs. PT and PA imaging revealed more profound spatial hemoglobin heterogeneity in sRBCs than in nRBCs, which can be associated with the presence of HbS clusters with high local absorption. This hypothesis was confirmed in nonlinear mode through nanobubble formation around overheated HbS clusters accompanied by spatially selective signal amplification. More profound differences in absorption of sRBCs than in nRBCs led to notable increase in PA signal fluctuation (fluctuation PAFC mode) as an indicator of SCD. The obtained data suggest that noninvasive label-free fluctuation PAFC has a potential for real-time enumeration of sRBCs both <i>in vitro</i> and <i>in vivo</i>.
Oligosaccharides and Peptide Displayed on an Amphiphilic Polymer Enable Solid Phase Assay of Hapten Specific Antibodies (2014)

Copovidone, a copolymer of vinyl acetate and N-vinyl-2-pyrrolidone, was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization, and after deacetylation the polymer was functionalized by introduction of amino, azide, and alkyne pendant groups to allow attachment of glycans and peptide. Candida albicans β-mannan trisaccharides 1 and 2 and M. tuberculosis arabinan hexasaccharide 3 with appropriate tethers were conjugated to the polymers by squarate or click chemistry. C. albicans T-cell peptide 4 bearing a C-terminal ε-azidolysine was also conjugated to copovidone by click chemistry. The resulting conjugates provide convenient non-protein-based antigens that are readily adsorbed on ELISA plates, and display excellent characteristics for assay of antibody binding to the haptenic group of interest. Copovidone and BSA glycoconjugates exhibited similar adsorption characteristics when used to coat ELISA plates, and both conjugates were optimal when used as coating solutions at low nanogram/mL concentrations. Provided that the copovidone conjugated glycan is stable to acid, assay plates can be easily processed for reuse at least three times without detectable variation or degradation in ELISA readout.
Enterprise Content and Search Management for Building Digital Platforms (2016)

"Provides modern enterprises with the tools to create a robust digital platform utilizing proven best practices, practical models, and time-tested techniques Contemporary business organizations can either embrace the digital revolution&mdash;or be left behind. Enterprise Content and Search Management for Building Digital Platforms provides modern enterprises with the necessary tools to create a robust digital platform utilizing proven best practices, practical models, and time-tested techniques to compete in the today&rsquo;s digital world. Features include comprehensive discussions on content strategy, content key performance indicators (KPIs), mobile-first strategy, content assessment models, various practical techniques and methodologies successfully used in real-world digital programs, relevant case studies, and more.
Manipulation of Gold Nanorod Physicochemical Properties to Enhance Biocompatibility, Uptake and Intracellular Preservation of Optical Properties for Bio-Imaging and Plasmonic Photo-Therapeutic Applications (2015)

Manipulation of Gold Nanorod Physicochemical Properties to Enhance Biocompatibility, Uptake and Intracellular Preservation of Optical Properties for Bio-Imaging and Plasmonic Photo Therapeutic Applications
Buffering plasmons in nanoparticle waveguides at the virtual-localized transition (2010)

We study the plasmonic energy transfer from a locally excited nanoparticle (LE-NP) to a linear array of small NPs and we obtain the parametric dependence of the response function. An analytical expression allows us to distinguish the extended resonant states and the localized ones, as well as an elusive regime of virtual states. This last appears when the resonance width collapses and before it becomes a localized state. Contrary to common wisdom, the highest excitation transfer does not occur when the system has a well defined extended resonant state but just at the virtual-localized transition, where the main plasmonic modes have eigenfrequencies at the passband edge. The slow group velocity at this critical frequency enables the excitation buffering and hence favors a strong signal inside the chain. A similar situation should appear in many other physical systems. The extreme sensitivity of this transition to the waveguide and LE-NP parameters provides new tools for plasmonics.
Family response to critical illness (2011)

Visits after discharge, support groups, and clinics have been proposed for assessing the need for professional referrals as well as for treating family members when psychological illness persists. Studies evaluating these measures are reviewed.
Development of patterns for nanoscale strain measurements: I. Fabrication of imprinted Au webs for polymeric materials (2004)

A method is presented for patterning polymers with nanoscale gold networks and using the pattern to measure strain in the polymer. A gold film is first coated on a porous alumina template. After coating, the template is impressed into a polymer, and the template is dissolved to leave a continuous metal network on or slightly below the surface of the polymer. The network has a random structure and is electrically conductive and has potential applicability to structural health monitoring. We show that it can be used as a means of measuring deformation through changes in electrical conductivity and continuity and also as a means to measure local material response during controlled loading.
Transverse strain responses in electrostrictive poly(vinylidene fluoride-trifluoroethylene) films and development of a dilatometer for the measurement (1999)

A dilatometer based on the cantilever beam concept has been developed. The dilatometer is easy to use and capable of measuring transverse strain response of soft polymer films in a broad strain range (from 10−7 to 10−1) without mechanical constraining of the sample. It is capable of detecting strain over a relatively wide frequency range from mHz to above 100 Hz under different load and temperature. Using the setup, the electric field induced transverse strains of the electrostrictive poly(vinylidene fluoride-trifluoroethylene) copolymer films were characterized which shows that a large transverse strain can be achieved in this class of polymer. In addition, the effect of mechanical tensile load on the transverse strain was also evaluated and the results show that the strain response will be affected by the load. However, depending on the load level, the strain response of the polymer film under a given electric field may increase or decrease with load. Based on the phenomenological theory, it is shown that for a ferroelectric based material, the mechanical load will shift the Curie temperature. Hence, to a large extent, the change of the strain response with load observed here can be understood by linking it to the strain change with temperature.
Germanium and Silicon Nanocrystal Thin-Film Field-Effect Transistors from Solution (2010)

Germanium and silicon have lagged behind more popular II-VI and IV-VI semiconductor materials in the emerging field of semiconductor nanocrystal thin film devices. We report germanium and silicon nanocrystal field-effect transistors fabricated by synthesizing nanocrystals in a plasma, transferring them into solution, and casting thin films. Germanium devices show n-type, ambipolar, or p-type behavior depending on annealing temperature with electron and hole mobilities as large as 0.02 and 0.006 cm(2) V(-1) s(-1), respectively. Silicon devices exhibit n-type behavior without any postdeposition treatment, but are plagued by poor film morphology.
Hydrocolloid interactions useful in food systems (1982)

Some of the useful interactions of hydrocolloid interactions when used as food additives are reviewed, relating to modification of flow properties, reduced protein reactivity, increased solubility, viscosity synergism, and gel formation. These materials, commonly referred to as gums and usually classified as polysaccharides, are soluble or dispersible in water and function as a water control by thickening and/or gelling. The characteristics and function of the more prominent hydrocolloids are separately discussed: agar, carrageenan, gelatin, hydroxypropylcellulose, microcrystalline cellulose, sodium carboxymethylcellulose, and xanthan gum. Characteristics of each gum are based upon its viscosity-producing capacity when dispersed in water. This capacity allows gums a variety of functions in foods (e.g., binding, coating, suspending, stabilizing, gelling, emulsifying, thickening). Applications of these gums include their use in farinaceous foods, frozen and prepared desserts, beverages, confectionery, dressings, sauces, and dairy products. The solution properties of 1 gum often can be modified by interactions with other gums, enhancing their flexibility and use. (wz)