gebhart/patrepeval huggingface dataset:
Solubility of Ferrous Iron in Aqueous Ammoniacal Solutions (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolubility of Ferrous Iron in Aqueous Ammoniacal SolutionsD. J. Klocke and A. Norman HixsonCite this: Ind. Eng. Chem. Process Des. Dev. 1972, 11, 1, 141–146Publication Date (Print):January 1, 1972Publication History Published online1 May 2002Published inissue 1 January 1972https://pubs.acs.org/doi/10.1021/i260041a028https://doi.org/10.1021/i260041a028research-articleACS PublicationsRequest reuse permissionsArticle Views719Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Rehabilitación, educación y capacitación para el empleo (2000)

Discord in the estimated gene trees among loci can be attributed to both the process of mutation and incomplete lineage sorting. Effectively modeling these two sources of variation--mutational and coalescent variance--provides two distinct challenges for phylogenetic studies. Despite extensive investigation on mutational models for gene-tree estimation over the past two decades and recent attention to modeling of the coalescent process for phylogenetic estimation, the effects of these two variances have yet to be evaluated simultaneously. Here, we partition the effects of mutational and coalescent processes on phylogenetic accuracy by comparing the accuracy of species trees estimated from gene trees (i.e., the actual coalescent genealogies) with that of species trees estimated from estimated gene trees (i.e., trees estimated from nucleotide sequences, which contain both coalescent and mutational variance). Not only is there a significant contribution of both mutational and coalescent variance to errors in species-tree estimates, but the relative magnitude of the effects on the accuracy of species-tree estimation also differs systematically depending on 1) the timing of divergence, 2) the sampling design, and 3) the method used for species-tree estimation. These findings explain why using more information contained in gene trees (e.g., topology and branch lengths as opposed to just topology) does not necessarily translate into pronounced gains in accuracy, highlighting the strengths and limits of different methods for species-tree estimation. Differences in accuracy scores between methods for different sampling regimes also emphasize that it would be a mistake to assume more computationally intensive species-tree estimation procedures that will always provide better estimates of species trees. To the contrary, the performance of a method depends not only on the method per se but also on the compatibilities between the input genetic data and the method as determined by the relative impact of mutational and coalescent variance.
Synthesis, crystal and electronic structure, anticancer activity of ruthenium(II) arene complexes with thiosemicarbazones (2013)

A series of half‐sandwich ruthenium(II) arene complexes [( η 6 ‐ p ‐cymene)Ru II (R‐BzTSC)Cl]Cl 1 , 2 , 3 (BzTSC = benzaldehyde thiosemicarbazone and R = H, CH 3 and C 6 H 5 ) have been synthesized and characterized by IR, 1 H NMR, UV‐visible, electrospray ionization mass spectrometry and elemental analysis. The single‐crystal structures of 1 and 3 have been determined. The molecular orbitals and electronic absorption spectra of the compounds have been calculated using the DFT and TDDFT methods. The in vitro antiproliferative activities of these complexes have been evaluated against four human cancer cell lines (CNE, H292, SKBR3 and Hey1‐B), and 3 is proved to be the most efficient inhibitor, with IC 50 values of 20, 31, 10 and 34 μ m , respectively. Copyright © 2013 John Wiley & Sons, Ltd.
Canadian dog owners' use and perceptions of cannabis products. (2019)

The legal market for recreational and medicinal cannabis for human consumption is growing worldwide. At the same time, marketing of cannabis products for use in pets is expanding. Yet, there is little research exploring the effects of cannabis use in veterinary medicine. This study used an anonymous, online survey to assess Canadian pet owners' reasons for purchasing cannabis products for their dogs, and their perceptions regarding efficacy of these treatments. Owners purchased cannabis products for treatment of pain, inflammation, and anxiety in dogs, and perceived these preparations to be equally or more effective than conventional medications. Most owners reported only minimal side effects in their dogs. Despite indicating comfort in discussing canine cannabis administration with their veterinarian, most owners relied on commercial websites for product information. The main reasons for choosing cannabis products were the ability to use as an adjuvant to other therapies, and the perception of it being a natural substance. Given this information, it is incumbent upon veterinarians to appropriately counsel their clients, and also to advocate for evidence-based studies to evaluate the efficacy of cannabis use in non-human species.
Near‐infrared multichannel Raman spectroscopy toward real‐time <i>in vivo</i> cancer diagnosis (2002)

Abstract Using a newly developed InP/InGaAsP multichannel detector, we developed a near‐infrared Raman spectroscopic system that can measure human tissues efficiently without interference from fluorescence. This enabled us to measure an in vivo Raman spectrum of live human tissue (skin) in 1 min using fiber probe optics. By applying this system to human lung tissues, we found that Raman spectroscopy makes a clear distinction not only between normal and cancerous tissues but also between two different types of lung carcinomas. The results indicate a promising future for the non‐invasive real‐time Raman diagnosis of cancers. Copyright © 2002 John Wiley & Sons, Ltd.
An alternate design paradigm for robust spin-torque transfer magnetic RAM (STT MRAM) from circuit/architecture perspective (2009)

Spin-Torque Transfer Magnetic RAM (STT MRAM) is a promising candidate for future embedded applications. It provides desirable memory attributes such as fast access time, low cost, high density and non-volatility. However, variations in process parameters can lead to a large number of cells to fail, severely affecting the yield of the memory array. In this paper, we provide a thorough analysis of the impact of design parameters on parametric failures due to process variations. To achieve high memory yield without incurring expensive technology modification, we developed an alternate design paradigm ---circuit/architecture co-design --- to take advantage of different levels of design hierarchy (circuit and architecture) to improve the yield and memory density. The technique decouples the conflicting design requirements for read stability/writability and density. Consequently, the memory cell failure probability reduces by 48% and cell area reduces by 21% with negligible performance degradation (~0.4%).
Selection of motile nonchemotactic mutants of Escherichia coli by field-flow fractionation. (1991)

We have developed a chromatographic method for isolating bacterial cells that are motile but nonchemotactic. Separation of strains of different phenotype occurs along a thin horizontal channel between two stirred chambers, the lower one containing a chemical attractant. The channel is bounded above and below by rigid filters, permeable to the attractant but not to the bacteria. The lower part of the channel is occupied by a porous plate comprising a vertical array of capillary tubes. An aliquot of cells is injected at one end of the channel and eluted by continuous flow of cell-free medium. Fluid leaving the other end of the channel is collected in a fraction collector. Cells that respond to the gradient swim to the bottom of the channel where they are retarded by the capillary array. Nonmotile cells sink to the bottom and are trapped in a similar manner. Motile cells that fail to respond to the gradient diffuse across the full height of the channel and, thus, travel through the apparatus at the average velocity of the eluent. When mixed with wild-type cells at a ratio of 1:1000 and subjected to an aspartate gradient, aspartate-blind cells were recovered quantitatively. The enrichment was approximately 200 to 1. The wild-type cells that survived the selection had a poorly motile phenotype.
Distillation columns with vertical partitions (1987)

Abstract Distillation columns with vertical partitions can separate a feed mixture into 3 or 4 pure fractions. Compared to other column arrangements, their investment costs and energy consumption are lower. Production columns show good results and are easily controlled. Conventional distillation columns produce only 2 pure product streams at the top and at the bottom of the column. Side products are contaminated by light or heavy components, depending on the location of the side stream in the rectifying or stripping section. This disadvantage is set aside by using a distillation column with a vertical partition. The internal separation wall prevents lateral mixing of liquid and vapour in the central part of the column, forming there separate feed and outlet sections. In the presence of a vertical partition, 3 or 4 pure fractions can be obtained in a single distillation step. This is particularly advantageous when heat sensitive components are to be separated. On account of good thermodynamic properties, the energy consumption is 20 to 35% lower than that of other distillation arrangements. The control behaviour is similar or better than that of conventional distillation columns.
Aqueous Peroxyoxalate Chemiluminescence. (1982)

A quantum yield of 7.2% in aqueous solution has been obtained from the reaction of hydrogen peroxide with bis(N-2-(N'-methyl-2'-pyridinium)ethyl-N-trifluoromethylsulfonyl)oxamide in the presence of sulfonated rubrene as fluorescer. Light capacity of this system is 62 lumen hours per liter of solution. A system using bis-hexylrubrene in an emulsified solvent gave a quantum yield of 8.3%. A record high quantum yield of 34% in an organic solvent was achieved with bis-(N-(2,4,5-trichlorophenyl)-N-trifluoromethanesulfonyl)oxamide, hydrogen peroxide and a fluorescer. (Author)
<i>DICER1</i> Mutations in Familial Pleuropulmonary Blastoma (2009)

Pleuropulmonary blastoma (PPB) is a rare pediatric lung tumor that is often part of an inherited cancer syndrome. PPBs consist of mesenchymal cells that are susceptible to malignant transformation and cysts lined by epithelial cells. In a subset of patients, overgrowth of the cysts by mesenchymal cells leads to sarcoma formation. Here, we show that 11 multiplex PPB families harbor heterozygous germline mutations in DICER1, a gene encoding an endoribonuclease critical to the generation of small noncoding regulatory RNAs. Expression of DICER1 protein was undetectable in the epithelial component of PPB tumors but was retained in the malignant mesenchyme (sarcoma). We hypothesize that loss of DICER1 in the epithelium of the developing lung alters the regulation of diffusible factors that promote mesenchymal proliferation.
Regulation of two phosphatases and a cyclic phosphodiesterase of Salmonella typhimurium (1977)

The regulation of three Salmonella typhimurium phosphatases in reponse to different nutritional limitations has been studied. Two enzymes, an acid hexose phosphatase (EC 3.1.3.2) and a cyclic phosphodiesterase (EC 3.1.4.d), appear to be regulated by the cyclic adenosine 3' ,5'-monophosphate (AMP) catabolite repression system. Levels of these enzymes increased in cells grown on poor carbon sources but not in cells grown on poor nitrogen or phosphorus sources. Mutants lacking adenyl cyclase did not produce elevated levels of these enzymes in response to carbon limitation unless cyclic AMP was supplied. Mutants lacking the cyclic AMP receptor protein did not produce elevated levels of these enzymes in response to carbon limitation regardless of the presence of cyclic AMP. Since no specific induction of either enzyme could be demonstrated, these enzymes appear to be controlled solely by the cyclic AMP system. Nonspecific acid phsphatase activity (EC 3.1.3.2) increased in response to carbon, nitrogen, phosphorus, or sulfur limitation. The extent of the increase depended on growth rate, with slower growth rates favoring greater increases, and on the type of limitation. Limitation for either carbon or phosphorus resulted in maximum increases, whereas severe limitation of Mg2+ caused only a slight increase. The increase in nonspecific acid phosphatase during carbon limitation was apparently not mediated by the catabolite repression system since mutants lacking adenyl cyclase or the cyclic AMP receptor protein still produced elevated levels of this enzyme during carbon starvation. Nor did the increase during phosphorus limitation appear to be mediated by the alkaline phosphatase regulatory system. A strain of Salmonella bearing a chromosomal mutation, which caused constitutive production of alkaline phosphatase (introduced by an episome from Escherichia coli), did not have constitutive levels of nonspecific acid phosphatase.
New Geometric Interpretation and Analytic Solution for Quadrilateral Reconstruction (2014)

A new geometric framework, called generalized coupled line camera (GCLC), is proposed to derive an analytic solution to reconstruct an unknown scene quadrilateral and the relevant projective structure from a single or multiple image quadrilaterals. We extend the previous approach developed for rectangle to handle arbitrary scene quadrilaterals. First, we generalize a single line camera by removing the centering constraint that the principal axis should bisect a scene line. Then, we couple a pair of generalized line cameras to model a frustum with a quadrilateral base. Finally, we show that the scene quadrilateral and the center of projection can be analytically reconstructed from a single view when prior knowledge on the quadrilateral is available. A completely unknown quadrilateral can be reconstructed from four views through non-linear optimization. We also describe a improved method to handle an off-centered case by geometrically inferring a centered proxy quadrilateral, which accelerates a reconstruction process without relying on homography. The proposed method is easy to implement since each step is expressed as a simple analytic equation. We present the experimental results on real and synthetic examples.
<i>De novo</i> Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation (2010)

Activation of de novo lipogenesis in cancer cells is increasingly recognized as a hallmark of aggressive cancers and has been implicated in the production of membranes for rapid cell proliferation. In the current report, we provide evidence that this activation has a more profound role. Using a mass spectrometry-based phospholipid analysis approach, we show that clinical tumor tissues that display the lipogenic phenotype show an increase in the degree of lipid saturation compared with nonlipogenic tumors. Reversal of the lipogenic switch in cancer cells by treatment with the lipogenesis inhibitor soraphen A or by targeting lipogenic enzymes with small interfering RNA leads to a marked decrease in saturated and mono-unsaturated phospholipid species and increases the relative degree of polyunsaturation. Because polyunsaturated acyl chains are more susceptible to peroxidation, inhibition of lipogenesis increases the levels of peroxidation end products and renders cells more susceptible to oxidative stress-induced cell death. As saturated lipids pack more densely, modulation of lipogenesis also alters lateral and transversal membrane dynamics as revealed by diffusion of membrane-targeted green fluorescent protein and by the uptake and response to doxorubicin. These data show that shifting lipid acquisition from lipid uptake toward de novo lipogenesis dramatically changes membrane properties and protects cells from both endogenous and exogenous insults. These findings provide important new insights into the role of de novo lipogenesis in cancer cells, and they provide a rationale for the use of lipogenesis inhibitors as antineoplastic agents and as chemotherapeutic sensitizers.
P4P: A Practical Framework for Privacy-Preserving Distributed Computation (2007)

Privacy is becoming an increasingly important issue in electronic commerce and other online activities that are growing in popularity. This work introduces a framework, called Peers for Privacy (P4P), for implementing many useful algorithms with provable privacy and adequate efficiency in a realistic adversary model at a reasonably large scale. The basic idea is to decompose an algorithm into a series of addition-only steps, which have very efficient private implementation using cryptographic tools. This simple model is surprisingly general and supports many algorithms prevalent in distributed data mining. Examples include linear algorithms like voting and summation, as well as nonlinear algorithms such as regression, classification, SVD, PCA, <i>k</i>-means, ID3, machine learning algorithms based on Expectation Maximization (EM), etc. In fact all algorithms in the statistical query model are supported. <p> The computation of the sums is based on a highly efficient verifiable secret sharing (VSS) scheme that allows secret-shared arithmetic operations to be done over small fields (e.g. 32 or 64 bits) where private arithmetic operations have the same cost as normal arithmetic. This thesis shows that this paradigm admits efficient zero-knowledge tools that can be used to verify the properties of user data such as equality and boundedness. These tools provide practical mechanisms to deal with cheating users. One such tool is an extremely efficient zero-knowledge proof that verifies the L2-norm of the user data is bounded by a constant. This is to prevent a malicious user from exerting too much influence on the computation. The verification uses a linear number of inexpensive small field operations, and only a logarithmic number of large-field (1024 bits or more) cryptographic operations, and can achieve orders of magnitude reduction in running time over standard techniques (from hours to seconds) for large-scale problems. Concrete examples are given to demonstrate how the framework supports private computation of popular algorithms such as SVD, link analysis and association rule mining. The thesis also includes schemes for scalable multicast encryption and bidirectional group communication. They provide secure data transmission support for the type of communication pattern required by the P4P framework and many other group-oriented applications
Cluster-based adaptive information retrieval (2002)

The paper discusses the issues involved in the design of a complete information retrieval system based on user-oriented clustering schemes. Clusters are constructed taking into account the users' perception of similarity between documents. The system accumulates feed-back from the users and employs it to construct user-oriented clusters. An optimization function to improve the effectiveness of the clustering process is developed. A retrieval process based on the clustering scheme is described. The system developed is experimentally validated and compared with existing systems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Antioxidant rich grape pomace extract suppresses postprandial hyperglycemia in diabetic mice by specifically inhibiting alpha-glucosidase (2010)

This is the first report that the grape pomace extracts selectively and significantly inhibits intestinal α-glucosidase and suppresses postprandial hyperglycemia in diabetic mice. The antioxidant and anti-postprandial hyperglycemic activities demonstrated on the tested grape pomace extract therefore suggest a potential for utilizing grape pomace-derived bioactive compounds in management of diabetes.
A system for dynamic playlist generation driven by multimodal control signals and descriptors (2011)

This work describes a general approach to multimedia playlist generation and description and an application of the approach to music information retrieval. The example of system that we implemented updates a musical playlist on the fly based on prior information (musical preferences); current descriptors of the song that is being played; and fine-grained and semantically rich descriptors (descriptors of user's gestures, of environment conditions, etc.). The system incorporates a learning system that infers the user's preferences. Subjective tests have been conducted on usability and quality of the recommendation system.
A Provenance-Aware Access Control Framework with Typed Provenance (2015)

Provenance is a directed graph that captures historical information about data items in Provenance-Aware Systems (PAS). A variety of access control models and policy languages specific to PAS have been recently discussed in literature. However, it is still not clear how to efficiently specify provenance-aware access control policies and how to effectively enforce these policies with respect to complex provenance graph that can only be captured at run-time. To this end, we design and implement a provenance-aware access control framework with a layered architecture that features an abstract layer, including a Typed Provenance Model (TPM) and a set of TPM interpreters. TPM includes a set of abstract provenance types enabling efficient specification of provenance-aware policies. New provenance types can be composed of extant ones for specifying new policies. TPM interpreters can be integrated to enable the policy enforcement with respect to provenance graphs in different physical representations. By treating provenance types as special attributes, the proposed framework enables an adoption of provenance-aware access control in existing attribute-based access control frameworks, such as XACML-compliant ones. We implement the proposed framework by extending SUN's XACML implementation and show that it facilitates the specification of provenance-aware policies in XACML with minor extensions. We also analyze the performance of the proposed framework.
2020 Second issue (2020)

We publish the second issue of our journal in 2020 while our country and the world are still struggling with our Covid -19 pandemic. We continue to take care not to disrupt our academic studies while we are fighting with this infectious disease as a country in this challenging period. In this issue of our journal, there are 17 articles and 3 case report in the fields of dentistry, nursing, orthopedics, family medicine, gynecology, nephrology, emergency medicine, parasitology, neurosurgery, microbiology, medical biology, psychiatry, cardiology, biostatistics and medical informatics. Endless thanks to everyone who contributed in this issue. We hope to publish the second issue of our journal on beautiful days.