gebhart/patrepeval huggingface dataset:
Reversal of Raf-1 Activation by Purified and Membrane-Associated Protein Phosphatases (1995)

The Raf-1 protein kinase participates in transduction of mitogenic signals, but its mechanisms of activation are incompletely understood. Treatment of human Raf-1 purified from insect Sf9 cells co-expressing c-H-Ras and Src(Y527F) (in which phenylalanine replaces tyrosine at residue 527) with either serine-threonine or tyrosine phosphatases resulted in enzymatic inactivation of Raf-1. Inactivation of purified Raf-1 was blocked by addition of either the 14-3-3 zeta protein or heat shock protein 90. Loading of plasma membranes from transformed cells with guanosine triphosphate (GTP) resulted in inactivation of endogenous or exogenous Raf-1; inactivation was blocked by inclusion of protein phosphatase inhibitors. These results suggest the existence of protein phosphatases in the cell membrane that are regulated by GTP and are responsible for Raf-1 inactivation.
Localizer Traveling Wave Antenna Development. (1976)

Federal Aviation Administration Systems and Research and Development efforts have resulted in the development of a set of Instrument Landing System localizer antenna arrays of the traveling wave type. These arrays including integral monitors have been shown capable of overcoming the major shortcomings associated with earlier antennas. The results of this effort are summarized. Distinguishing performance characteristics are pointed out for each of the so-called Type O, 1A, 1B and II antenna arrays.
Noise-Enabled Precision Measurements of a Duffing Nanomechanical Resonator (2005)

We report quantitative measurements of the nonlinear response of a radio frequency mechanical resonator with a very high quality factor. We measure the noise-free transitions between the two basins of attraction that appear in the nonlinear regime, and find good agreement with theory. We measure the transition rate response to controlled levels of white noise, and extract the basin activation energy. This allows us to obtain precise values for the relevant frequencies and the cubic nonlinearity in the Duffing oscillator, with applications to parametric sensing.
The Glomerular Slit Diaphragm Is a Modified Adherens Junction (2000)

The glomerular slit diaphragm between podocyte foot processes shares typical morphologic features with an adherens junction. Differentiated cultured podocytes form cellular structures comparable to filtration slits in vivo. At those sites, zonula occludens-1 (ZO-1) was coexpressed with P-cadherin as well as with alpha-, beta-, and gamma-catenin. In situ, P-cadherin was detected at the slit diaphragm in association with ZO-1 as shown by confocal microscopy and immunogold double labeling electron microscopy. P-cadherin expression in vivo and in vitro was confirmed by reverse transcription-PCR. These findings led to the concept that the slit diaphragm represents an adherens junction composed of P-cadherin, alpha-, beta-, and gamma-catenin, and ZO-1. In contrast to an adherens junction of a similar composition recently described in cultured fibroblasts, the slit diaphragm complex does not contain vinculin, which was found in nearby focal contacts. A P-cadherin-based adherens junction is well-suited to explain the zipper-like structure of the slit diaphragm. The present study should allow new avenues leading to the identification of additional slit diaphragm-associated proteins conferring specificity to this unique cell junction.
Experimental Study of a Membrane Antenna Surface Adaptive Control System (2011)

Due to their ultra lightweight and high packaging efficiency, membrane reflectors are getting more and more attention for mission architectures that need extremely large in-space deployable antennas. However, maintaining the surface shape of a membrane reflector to the instrument precision requirements is a very challenging problem. This experimental study investigated using PVDF membrane piezoelectric material as actuators to control the surface figures of membrane reflectors. The feasibility of this approach is demonstrated by several sets of test results.
Aggregation of an octasubstituted phthalocyanine in dodecane solution (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAggregation of an octasubstituted phthalocyanine in dodecane solutionW. J. Schutte, M. Sluyters-Rehbach, and J. H. SluytersCite this: J. Phys. Chem. 1993, 97, 22, 6069–6073Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/j100124a047https://doi.org/10.1021/j100124a047research-articleACS PublicationsRequest reuse permissionsArticle Views701Altmetric-Citations134LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Design of Engineered Elastomeric Substrate for Stretchable Active Devices and Sensors (2018)

Abstract In the field of flexible electronics, emerging applications require biocompatible and unobtrusive devices, which can withstand different modes of mechanical deformation and achieve low complexity in the fabrication process. Here, the fabrication of a mesa‐shaped elastomeric substrate, supporting thin‐film transistors (TFTs) and logic circuits (inverters), is reported. High‐relief structures are designed to minimize the strain experienced by the electronics, which are fabricated directly on the pillars' surface. In this design configuration, devices based on amorphous indium‐gallium‐zinc‐oxide can withstand different modes of deformation. Bending, stretching, and twisting experiments up to 6 mm radius, 20% uniaxial strain, and 180° global twisting, respectively, are performed to show stable electrical performance of the TFTs. Similarly, a fully integrated digital inverter is tested while stretched up to 20% elongation. As a proof of the versatility of mesa‐shaped geometry, a biocompatible and stretchable sensor for temperature mapping is also realized. Using pectin, which is a temperature‐sensitive material present in plant cells, the response of the sensor shows current modulation from 13 to 28 °C and functionality up to 15% strain. These results demonstrate the performance of highly flexible electronics for a broad variety of applications, including smart skin and health monitoring.
Unsteady aerodynamic flow field analysis of the space shuttle configuration. Part 1: Orbiter aerodynamics (1976)

An analysis of the steady and unsteady aerodynamics of the space shuttle orbiter has been performed. It is shown that slender wing theory can be modified to account for the effect of Mach number and leading edge roundness on both attached and separated flow loads. The orbiter unsteady aerodynamics can be computed by defining two equivalent slender wings, one for attached flow loads and another for the vortex-induced loads. It is found that the orbiter is in the transonic speed region subject to vortex-shock-boundary layer interactions that cause highly nonlinear or discontinuous load changes which can endanger the structural integrity of the orbiter wing and possibly cause snap roll problems. It is presently impossible to simulate these interactions in a wind tunnel test even in the static case. Thus, a well planned combined analytic and experimental approach is needed to solve the problem.
Body scanning of dynamic posture (2006)

Purpose Aims to check the validity of measurements of dynamic postures recorded by a body scanner. Design/methodology/approach Measurements between various anatomical landmarks have been taken both manually and using a 3D body scanner so that the validity of the measurements might be assessed when dynamic postures are adopted. Mechanical measurements of changes in the body surface dimensions have been compared with figures produced by a body scanner for both the standard natural position and for five dynamic postures, which must be accommodated when designing high‐performance garments. Findings Although the 3D body scanner collects data almost instantaneously and without physical contact with the target surface, the readings taken in respect of dynamic poses showed significant variations from manually‐taken measurements, with discrepancies as large as 6.8 cm over a 16 cm distance. Research limitations/implications The research has only been carried out on a very limited number of subjects. However, significant differences between manual and automatic body measurements are clearly demonstrated. Practical implications The research showed that as there are as yet no universally‐accepted conventions for 3D scanner measurements, the results appear to be optimised for the natural anatomical position. Body‐scanners are not well‐suited to taking measurements of dynamic postures expected in sporting activities. Originality/value Measurements of anthropometric landmarks for high‐performance activities have not previously been assessed, and these results usefully indicate the limitations of current 3D scanning technology.
Spread spectrum: Principles and possible application to spectrum utilization and allocation (1978)

Because of the continuing demand for more telecommunication capacity, to serve the world's need for commerce and public safety, there is a continuing need for more efficient ways of sharing the radio spectrum. The conventional way of allocating the spectrum is by frequency division; however, for many kinds of services this is inefficient. Hence, it seems desirable to reexamine whether alternative procedures might not be necessary if the benefits of telecommunications are to be assured in the face of increased demand. Spreadspectrum techniques, which are based on principles antithetic to those currently used in spectrum allocation for reducing necessary bandwidth, seem to offer benefits for spectrum sharing, for some applications, superior to those of frequency division. This paper provides a tutorial summary of some of the principles upon which spread-spectrum systems have developed. It is hoped the reader might consider what role such techniques may play in future spectrum sharing and allocation opportunities.
The Magnetic Susceptibility of Nitrogen Dioxide (1932)

A method has been developed whereby sensitivities for volume susceptibilities as high as 3\ifmmode\times\else\texttimes\fi{}${10}^{\ensuremath{-}15}$ can be obtained. The main improvement in the method over that of other observers is in the construction of lighter test bodies and the use of smaller fibers. The method is applied to the measurement of the susceptibility of N${\mathrm{O}}_{2}$. The results agree within the limit of experimental uncertainties with Van Vleck's theoretical value for the molecular susceptibility of N${\mathrm{O}}_{2}$ namely, $\ensuremath{\chi}(\mathrm{N}{\mathrm{O}}_{2})=0.375\ensuremath{\chi}({\mathrm{O}}_{2})$. The susceptibility of ${\mathrm{N}}_{2}$${\mathrm{O}}_{4}$ comes in as a second order effect and the value $\ensuremath{\chi}({\mathrm{N}}_{2}{\mathrm{O}}_{4})=\ensuremath{-}30\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ \ifmmode\pm\else\textpm\fi{}20 percent is in fair agreement with the value $\ensuremath{\chi}({\mathrm{N}}_{2}{\mathrm{O}}_{4})=\ensuremath{-}25.8\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ obtained by T. Son\'e.
Object-Oriented Multimedia Annotation for Large-Scale Mapping System (1991)

Recently, advanced functions for multimedia mapping systems are developed as a part of large scale customer information service in public companies such as electric power, water, gas supply, etc. In these customer service systems, note information is required to be managed in a paper-less manner. The non-standard, temporary annotational information which was conventionally recorded as a note on a paper is necessary to be arranged in time order then classified by customers and to be made available as the customer database. Moreover, an advanced function that can easily retrieve the contents of these databases by specifying the customers’ house frame on the displayed map is required. For this purpose, a new method of object oriented management and an arrangement method which classifies data according to different viewpoints are introduced into the management of these annotational information. By these new methods, a high performance annotational management method, which has few dependence to each media and which enables easy hierarchical retrieval was realized. In this paper, we introduce the contents of object oriented annotational information management method, and result of applying them to the real multimedia mapping system.
Error-correcting codes for list decoding (1991)

In the list-of-L decoding of a block code the receiver of a noisy sequence lists L possible transmitted messages, and is in error only if the correct message is not on the list. Consideration is given to (n,e,L) codes, which correct all sets of e or fewer errors in a block of n bits under list-of-L decoding. New geometric relations between the number of errors corrected under list-of-1 decoding and the (larger) number corrected under list-of-L decoding of the same code lead to new lower bounds on the maximum rate of (n,e,L) codes. They show that a jammer who can change a fixed fraction p<1/2 of the bits in an n-bit linear block code cannot prevent reliable communication at a positive rate using list-of-L decoding for sufficiently large n and an L<or=n. The new bounds are stronger for small n, but weaker for fixed e/n in the limit of large n and L than known random coding bounds.<<ETX>>
Patient feature based dosimetric Pareto front prediction in esophageal cancer radiotherapy (2015)

It is feasible to use patients' anatomic and dosimetric features to generate a predicted Pareto front. Additional samples and further studies are required improve the prediction model.
Suicidal emperipolesis: a process leading to cell-in-cell structures, T cell clearance and immune homeostasis. (2015)

"Suicidal emperipolesis" is one of the most recently reported processes leading to cell-in-cell structures that promote cell death. This process was discovered in studies investigating the fate of autoreactive CD8 T cells activated within the liver. Recently, we reported that activated T cells invaded hepatocytes, formed transient cell-in-cell structures, and were rapidly degraded within endosomal/lysosomal compartments by a non-apoptotic pathway. Importantly, pharmacological inhibition of this process caused intrahepatic accumulation of tissue-reactive T cells and breach of immune tolerance. The characterization of the molecular mechanisms of suicidal emperipolesis is still in its infancy, but initial studies suggest this phenomenon is distinct from other reported cell-in-cell structures. As opposed to the formation of other cell-in-cell structures, suicidal emperipolesis takes place in a non-malignant environment, and without obvious pathology. It is therefore the first cell-in-cell structure described to have a role in maintaining homeostasis in normal physiology in higher organisms. T cell emperipolesis within hepatocytes has also been observed by pathologists in a range of chronic human liver pathologies. As T cell-in-hepatocyte structures resulting from suicidal emperipolesis are very transiently observed in normal physiology, their accumulation during liver disease would suggest that severe tissue injury is promoted by, or associated with, defective T cell clearance. In this review, we compare "suicidal emperipolesis" to other processes leading to cell-in-cell structures, and consider its potential biological roles in maintaining immune homeostasis and tolerance in the context of the hepatic environment.
Infrared differential interference contrast microscopy for 3D interconnect overlay metrology (2013)

One of the main challenges for 3D interconnect metrology of bonded wafers is measuring through opaque silicon wafers using conventional optical microscopy. We demonstrate here the use infrared microscopy, enhanced by implementing the differential interference contrast (DIC) technique, to measure the wafer bonding overlay. A pair of two dimensional symmetric overlay marks were processed at both the front and back sides of thinned wafers to evaluate the bonding overlay. A self-developed analysis algorithm and theoretical fitting model was used to map the overlay error between the bonded wafers and the interconnect structures. The measurement accuracy was found to be better than 1.0 micron.
The Nuclear Gene <i>Rf3</i> Affects the Expression of the Mitochondrial Chimeric Sequence R Implicated in S-Type Male Sterility in Maize (1997)

The mitochondrial genomes of maize plants exhibiting S-type cytoplasmic male sterility (cms-S) contain a repeated DNA region designated R. This region was found to be rearranged in the mitochondria of all cms-S cytoplasmically revertant fertile plants in all nuclear backgrounds analyzed. A 1.6-kb mRNA transcribed from the R region in mitochondria of sterile plants was absent from all cytoplasmic revertants examined. The nuclear gene Rf3, which suppresses the cms-S phenotype, was found to have a specific effect on the expression of the R sequence; the abundance of the major R transcripts, including the cms-S-specific 1.6-kb mRNA, is decreased in mitochondria of restored plants. Nucleotide sequence analysis of R has revealed similarities to the R1 plasmid found in some South American maize races with RU cytoplasm, to the M1 plasmid found in one source of Zea luxurians teosinte, to the atp9 mitochondrial gene and its 3' flanking sequence, and also to a region 3' to the orf221 gene. The derived amino acid sequence of the R region predicts two open reading frames (ORFs). These ORFs contain the similarities to R1, M1, atp9 and orf221. The present report reveals the chimeric nature of the R region, describes the complex effect of Rf3 on the expression of the R sequence and implicates R in the sterile phenotype of cms-S maize.
A fast sonar-based benthic object recognition model via extreme learning machine (2015)

The fast sonar-based object recognition turns out to be one of the most challenging topics in the underwater signal analysis. In this paper, we try to develop a fast benthic object recognition model via the extreme learning machine (ELM) on the basis of the structured geometrical feature extraction. Geometrical features such as major and minor axis, eccentricity, circularity and so on are employed to construct learning samples of ELM. The classifier based on ELM is used to recognize the target objects in sonar images. It has been shown in the simulation experiments that the proposed model could keep a quite good recognition performance with a much fast speed.
Fabrication of magnetic cryptomelane-type manganese oxide nanowires for water treatment (2010)

Superparamagnetic Fe(3)O(4) nanoparticles were successfully grafted onto the manganese oxide OMS-2 nanowires, and the synthesized material exhibits excellent magnetic separation and adsorption properties.
Dithiocarbamate complexes as radiopharmaceuticals for medical imaging (2012)

Over the past 30 years dithiocarbamate ligands have found application in radiopharmaceutical metal-ligand complexes to image a range of disease states. The vast majority of research and applications, and the widest range of complex structures, have involved radionuclides of technetium and rhenium. Considering the extent of coordination chemistry of dithiocarbamate ligands described elsewhere in this issue, the extent of radiopharmaceutical application with metallic radionuclides is surprisingly narrow. Here we summarise the types of radiopharmaceutical complexes studied and the uses, and potential uses, to which they have been put in nuclear medicine.
Effect of the enamel matrix derivative Emdogain<sup>®</sup> on the growth of periodontal pathogens in vitro (2002)

The results suggest that EMD has a positive effect on the composition of bacterial species in the post-surgical periodontal wound, by selectively restricting growth of periopathogens that could hamper the wound healing and reduce the outcome of regenerative procedures.
Proposal and feasibility study of a 6-level PSK modulation format based system for 100-Gb/s migration (2008)

A novel 6-level DPSK based system and an efficient signal generation method are proposed to achieve 2.5 bits/symbol coding, which enables 100 Gb/s system using 40 Gb/s device technology. Signal generation and reception are experimentally verified at 10.7 Gsymbol/s.
The influence of post-mortem conditions on the solubilities of muscle proteins (1964)

ULTRASONIC VIBRATIONS AND MICROSOMES 201 4. The activity of ultrasonically treated micro- somes could not be restored by polyuridylic acid.
Characterizing the Mechanical Properties of Composite Materials Using Tubular Samples (2001)

Application of composite materials to structures has presented the need for engineering analysis and modeling to understand the failure mechanisms. Unfortunately, composite materials, especially in a tubular geometry, present a situation where it is difficult to generate simple stress states that allow for the characterization of the ply-level properties. The present work focuses on calculating the mechanical characteristics, both on a global and local level, for composite laminate tubes. Global responses to axisymmetric test conditions (axial tension, torsion, and internal pressure) are measured on sections of the material. New analysis techniques are developed to use the global responses to calculate the ply level properties for tubular composite structures. Error analyses are performed to illustrate the sensitivity of the nonlinear regression methods to error in the experimental data. Ideal test matrices are proposed to provide the best data sets for improved accuracy of the property estimates. With these values, the stress and strain states can be calculated through the thickness of the material, enabling the application of failure criteria, and the calculation of failure envelopes.