gebhart/patrepeval huggingface dataset:
Novel Patch-Via-Spiral Resonators for the Development of Miniaturized Bandpass Filters With Transmission Zeros (2007)

A novel patch-via-spiral resonator based on the dual-metal-plane configuration is proposed and examined. With the microstrip patch on the top plane serving as a capacitor and linking to the quasi-lumped spiral inductor on the bottom plane through a connecting via, the proposed dual-plane resonator structure located on the opposite sides of the single substrate may form a miniaturized one in the printed-circuit board fabrication. By suitably combining the proposed patch-via-spiral resonators, useful coupled-resonator pairs may be constructed to simultaneously provide electric and magnetic couplings. Based on these coupled-resonator pairs, a second-order bandpass filter with multiple transmission zeros is realized without requiring either the cross-coupled path or the source-load coupling. For design purpose, the equivalent-circuit model is also derived and verified. In this study, a fourth-order patch-via-spiral bandpass filter with both good passband selectivity and miniaturized size of only 22.14 mm times5.08 mm (i.e., 0.188lambda <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g0</sub> times0.043lambda <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g0</sub> ) is implemented, where lambda <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g0</sub> denotes the guided wavelength of the 50-Omega microstrip line at center frequency
« Répondre à tous » (1997)

« Nous confondons sciemment le phénomène de l’écrit et celui de l’information, par peur de quelque chose qui ne serait ni rassurant ni très conforme à notre idée de la Raison, par peur de voir s’effondrer les idéaux de la communication. »P. LegendreParoles poétiques échappées du texteParis, 1982 : 10 Le point de départ factuel de notre enquête est la rencontre en 1992 avec une rédactrice du courrier présidentiel. La description qu’elle nous en fit attira notre attention sur ce qu’il convient ...
Novel agents in the treatment of multiple myeloma: a review about the future (2016)

Multiple myeloma (MM) is a disease that affects plasma cells and can lead to devastating clinical features such as anemia, lytic bone lesions, hypercalcemia, and renal disease. An enhanced understanding of MM disease mechanisms has led to new more targeted treatments. There is now a plethora of treatments available for MM. In this review article, our aim is to discuss many of the novel agents that are being studied or have recently been approved for the treatment of MM. These agents include the following: immunomodulators (pomalidomide), proteasome inhibitors (carfilzomib, marizomib, ixazomib, oprozomib), alkylating agents (bendamustine), AKT inhibitors (afuresertib), BTK inhibitors (ibrutinib), CDK inhibitors (dinaciclib), histone deacetylase inhibitors (panobinostat, rocilinostat, vorinostat), IL-6 inhibitors (siltuximab), kinesin spindle protein inhibitors (filanesib), monoclonal antibodies (daratumumab, elotuzumab, indatuximab, SAR650984), and phosphoinositide 3-kinase (PI3K) inhibitors.
A Review on Pilot-Scale Applications of Hydrothermal Treatment for Upgrading Waste Materials (2015)

In this paper, a review on applications of hydrothermal treatment (HTT) for upgrading waste materials was presented. This work was focused on pilot-scale HTT processes that applied to several kinds of waste for alternative solid biofuel production. The HTT utilizes subcritical water condition that has special properties as an organic solvent. With the temperature around 180-240 C and the corresponding pressure that keeps the water in the liquid phase, many reactions are induced by the subcritical water such as hydrolysis and dehydration. The waste materials that had been subjected to the HTT processes by pilot-scale reactors such as paper sludge, antibiotic residue, and municipal solid waste were reviewed herein. Moreover, a novel application of HTT on hospital waste treatment has been carried out in a pilot-scale level. Results showed positive effects and consistency with the previous research works. Thus, the HTT showed possibility to be an option for pretreating waste materials prior to final conversion processes.
Stepwise approach to establishing an ophthalmology wet laboratory (2009)

Wet laboratories (wet labs) play an increasingly important role in ophthalmology surgical residency training. We summarize the necessary components in establishing and maintaining a well-functioning wet lab and offer a stepwise guide for educators to improve the quality of the wet lab experience. We present 6 key factors in creating an ophthalmology wet lab; that is, setting up the physical space, establishing appropriate faculty and curriculum, obtaining the practice eye, stabilizing the eye, preparing the eye, and funding the wet lab.
VEGF overexpression enhances striatal neurogenesis in brain of adult rat after a transient middle cerebral artery occlusion (2006)

To elucidate whether vascular endothelial growth factor (VEGF) improves stroke-induced striatal neurogenesis, we intraventricularly injected human VEGF(165)-expressive plasmid (phVEGF) mixed with liposome into adult rats after a transient middle cerebral artery occlusion (MCAO). The results showed that EGFP, a reporter protein, positive cells appeared at 2 hr, further enhanced at 4 hr, reached the maximum at 3 days and still remained at 14 days after a single injection. Treatment with phVEGF increased angiogenesis, as indicated by double staining of vWF, a marker of endothelial cells, and 5'-bromodeoxyuridine (BrdU), a marker of cell proliferation. The phVEGF treatment dose-dependently reduced infarct volume of brain at 2 weeks after MCAO. The neuroprotection by VEGF could be obtained when the plasmid was injected within 2 hr after stroke. Moreover, VEGF overexpression significantly increased cell proliferation in the ipsilateral SVZ and the numbers of BrdU(+)-CRMP-4(+) and BrdU(+)-Tuj1(+), two markers of immature newborn neurons, and BrdU(+)-MAP-2(+), a marker of mature newborn neurons, cells in the ipsilateral striatum to MCAO. Present results show that VEGF plasmid treatment after stroke can significantly reduce infarct volume and enhance striatal neurogenesis in adult rat brain. This suggests that VEGF overexpression acquires significant functions of neuronal protection and repair in the injured brain, which provides a possibility to develop a novel therapeutic strategy for the patients with stroke.
Little-Parks oscillations of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi>T</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math>in patterned microstructures of the oxide superconductor<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">YBa</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Cu</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>7</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>: Experimental limits on fractional-statistics-particle theories (1990)

We report observation of Little-Parks oscillations in arrays with a 4-\ensuremath{\mu}${\mathrm{m}}^{2}$ plaquette area, fabricated from c^-axis-oriented ${\mathrm{YBa}}_{2}$${\mathrm{Cu}}_{3}$${\mathrm{O}}_{7}$ films. Near the mean-field transition temperature the magnitude of the oscillations implies a zero-temperature coherence length \ensuremath{\xi}(0)=15\ifmmode\pm\else\textpm\fi{}2 A\r{}. For temperatures more than 1 K below the mean-field transition, the magnitude of the oscillations increases dramatically, apparently signaling a crossover to the dynamics of a Josephson-coupled network. Precise experimental limits can be placed on the value of the flux quantum, severely restricting any anomalous value which may be proposed on the basis of fractional-statistics-particle theories.
Synthesis, characterization, and reactivity of triphenylsilyl, triphenylgermyl, and triphenylstannyl derivatives of zirconium and hafnium (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, characterization, and reactivity of triphenylsilyl, triphenylgermyl, and triphenylstannyl derivatives of zirconium and hafniumHee Gweon Woo, William P. Freeman, and T. Don TilleyCite this: Organometallics 1992, 11, 6, 2198–2205Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://pubs.acs.org/doi/10.1021/om00042a038https://doi.org/10.1021/om00042a038research-articleACS PublicationsRequest reuse permissionsArticle Views408Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Production of Anticapsin by <i>Streptomyces griseoplanus</i> (1971)

Anticapsin is a new fermentation product which inhibits formation of the hyaluronic acid capsule of Streptococcus pyogenes. Production of this metabolite in a complex medium by S. griseoplanus is enhanced by high levels of carbohydrate. A number of carbon sources support biosynthesis but sucrose is most effective, the optimum level being 150 g/liter. Neither glucose nor fructose, alone or in combination, serves as an equivalent substitute for sucrose. The addition of dibasic potassium phosphate to the medium further increases anticapsin production. Dissolved oxygen levels are important for synthesis and stability of the metabolite. Anticapsular activity diminishes rapidly in previously aerated broths which are held under static conditions. This decrease does not occur in pasteurized broths or unpasteurized filtrates.
Comparative functional role of PC7 and furin in the processing of the HIV envelope glycoprotein gp160 (1997)

The intracellular proteolytic processing of HIV envelope glycoprotein gp160 into gp120/gp41 is an essential step for virus infectivity. Several convertases, belonging to the pro-protein convertase family, have been proposed as candidate gp160 processing enzymes. Here we demonstrate using RT-PCR that resting human T4 lymphocytes weakly express PC7, furin, and PC5 mRNA whereas lymphocytes activated under conditions favoring HIV replication express 5-10-fold higher levels of furin and PC7. In this report, we examined the capability of the newly cloned convertase PC7 to cleave gp160 into gp120/gp41 and compared it to furin. This was carried out in a cell-based assay whereby both gp160 and the cognate convertase were co-expressed in the constitutively secreting BSC40 cells and in the regulated AtT20 cells, as well as using two in vitro assays which examined the cleavage of gp160 or of a synthetic peptide spanning the cleavage site. The data demonstrate that PC7 can cleave specifically and in a cell-type specific manner gp160 into gp120gp41, suggesting that both furin and PC7 are so far the major PC-like candidate gp160 convertase in T4 lymphocytes.
Abnormal Grain Growth of Off-Cube Grains in High Purity Aluminum Foils with Cube Texture (2005)

In present study, abnormally coarsened grains in high purity aluminum foils with cube texture ({100}〈001〉) after a final annealing was investigated using SEM/EBSP method. Most of abnormally coarsened grains had Goss ({110}〈001〉) or S ({123}〈634〉) orientations. The coarsened grains with Goss and S-orientations were surrounded by Σ5 and Σ7 coincidence boundaries, respectively. This result clarified that these coincidence boundaries would enhance the abnormal grain growth of Goss and S oriented grains. Grain boundary energy of sub-boundaries between cube-oriented grains provided the driving force for the abnormal grain growth. The distribution of Goss oriented grains in the partially annealed foils was characterized by SEM/EBSP method. This characterization revealed that many Goss-oriented grains were distributed in the transition band on the central layer of the sheets.
New Cytotoxic Cardenolide Glycoside from the Seeds of Cerbera manghas (2004)

A new cytotoxic cardenolide glycoside, 3beta-O-(2'-O-acetyl-alpha-L-thevetosyl)-14beta-hydroxy-7-en-5beta-card-20(22)-enolide, (7,8-dehydrocerberin), together with five known cardenolides, 17beta-neriifolin, deacetyltanghinin, tanghinin, cerberin and 2'-O-acetyl-cerleaside A were isolated from the seeds of Cerbera manghas L. Their structures were elucidated by 1D- and 2D-NMR techniques as well as UV, IR and mass spectral data. 7,8-Dehydrocerberin, deacetyltanghinin and tanghinin exhibited cytotoxic activities against oral human epidermoid carcinoma (KB), human breast cancer cell (BC) and human small cells lung cancer (NCI-H187).
Donor Solvent Mediated Reactions of Elemental Zinc and Sulfur, sans Explosion (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDonor Solvent Mediated Reactions of Elemental Zinc and Sulfur, sans ExplosionAtul K. Verma, Thomas B. Rauchfuss, and Scott R. WilsonCite this: Inorg. Chem. 1995, 34, 11, 3072–3078Publication Date (Print):May 1, 1995Publication History Published online1 May 2002Published inissue 1 May 1995https://pubs.acs.org/doi/10.1021/ic00115a038https://doi.org/10.1021/ic00115a038research-articleACS PublicationsRequest reuse permissionsArticle Views630Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Subdiaphragmatic vagotomy promotes tumor growth and reduces survival via TNFα in a murine pancreatic cancer model (2017)

This study analyses the effects of vagotomy on tumor growth and survival in a murine, pancreatic cancer model in wild-type and TNFα-knockout (-/-) mice.Throughout many operative procedures in the upper gastrointestinal tract the partial or complete transection of the vagus nerve or its local nerve fibers is unavoidable. Thereby its anti-inflammatory effects in residual tumor tissue may get lost. This effect may be mediated by tumor-associated macrophages (TAM) secreting TNFα.In an orthotopic murine pancreatic cancer model subdiaphragmatic vagotomy versus sham surgery was performed. The impact on tumor growth was monitored in wild type and TNFα -/- mice using MRI. TAMs as well as expression levels of TNFα were analyzed using immunohistochemistry. The role of TNFα on tumor growth and migration was examined in vitro. Vagotomised mice showed increased tumor growth with macroscopic features of invasive growth and had a shorter survival time. The loss of vagal modulation led to significantly increased TNFα levels in tumors and considerably elevated numbers of TAMs. In vitro TNFα significantly stimulated growth (p < 0.05) and migration (p < 0.05) of pancreatic cancer cells. TNFα -/- mice survived significantly longer after tumor implantation (p < 0.05), with vagotomy not affecting the prognosis of these animals (p > 0.05).Vagotomy can increase tumor growth and worsen survival in a murine pancreatic cancer model mediated through TAMs and TNFα. Hence, the suppression of TAMs and the modulation of TNFα dependent pathways could offer new perspectives in immunotherapies of pancreatic cancer patients especially with remaining vital tumor cells and lost vagal modulation.
The Transjugular Intrahepatic Portosystemic Shunt: An Update (2012)

The best available evidence supports the use of TIPS in secondary prevention of variceal bleeding and in refractory ascites, although TIPS is also commonly used for other indications such as Budd-Chiari syndrome, hepatic hydrothorax, and acute variceal hemorrhage. The TIPS procedure was revolutionized by the introduction of covered stents, which dramatically improved long-term shunt patency.
Cloning and characterization of murine 1-acyl-<i>sn</i>-glycerol 3-phosphate acyltransferases and their regulation by PPARα in murine heart (2005)

AGPAT (1-acyl-sn-glycerol 3-phosphate acyltransferase) exists in at least five isoforms in humans, termed as AGPAT1, AGPAT2, AGPAT3, AGPAT4 and AGPAT5. Although they catalyse the same biochemical reaction, their relative function, tissue expression and regulation are poorly understood. Linkage studies in humans have revealed that AGPAT2 contributes to glycerolipid synthesis and plays an important role in regulating lipid metabolism. We report the molecular cloning, tissue distribution, and enzyme characterization of mAGPATs (murine AGPATs) and regulation of cardiac mAGPATs by PPARalpha (peroxisome-proliferator-activated receptor alpha). mAGPATs demonstrated differential tissue expression profiles: mAGPAT1 and mAGPAT3 were ubiquitously expressed in most tissues, whereas mAGPAT2, mAGPAT4 and mAGPAT5 were expressed in a tissue-specific manner. mAGPAT2 expressed in in vitro transcription and translation reactions and in transfected COS-1 cells exhibited specificity for 1-acyl-sn-glycerol 3-phosphate. When amino acid sequences of five mAGPATs were compared, three highly conserved motifs were identified, including one novel motif/pattern KX2LX6GX12R. Cardiac mAGPAT activities were 25% lower (P<0.05) in PPARalpha null mice compared with wild-type. In addition, cardiac mAGPAT activities were 50% lower (P<0.05) in PPARalpha null mice fed clofibrate compared with clofibrate fed wild-type animals. This modulation of AGPAT activity was accompanied by significant enhancement/reduction of the mRNA levels of mAGPAT3/mAGPAT2 respectively. Finally, mRNA expression of cardiac mAGPAT3 appeared to be regulated by PPARalpha activation. We conclude that cardiac mAGPAT activity may be regulated by both the composition of mAGPAT isoforms and the levels of each isoform.
Matching large XML schemas (2004)

Current schema matching approaches still have to improve for very large and complex schemas. Such schemas are increasingly written in the standard language W3C XML schema, especially in E-business applications. The high expressive power and versatility of this schema language, in particular its type system and support for distributed schemas and name-spaces, introduce new issues. In this paper, we study some of the important problems in matching such large XML schemas. We propose a fragment-oriented match approach to decompose a large match problem into several smaller ones and to reuse previous match results at the level of schema fragments.
NMR Studies of the Species Present in Cross-Coupling Catalysis Systems Involving Pd(η<sup>3</sup>-1-Ph-C<sub>3</sub>H<sub>4</sub>)(η<sup>5</sup>-C<sub>5</sub>H<sub>5</sub>) and [Pd(η<sup>3</sup>-1-Ph-C<sub>3</sub>H<sub>4</sub>)Cl]<sub>2</sub> Activated by PBu<sup>t</sup><sub>3</sub>, XPhos, and Mor-Dalphos: Nonexistence of Pd(XPhos)<sub><i>n</i></sub> and Pd(Mor-Dalphos)<sub><i>n</i></sub> (<i>n</i> = 1, 2) at Moderate Temperatures (2014)

The compounds Pd(η3-1-Ph-C3H4)(η5-C5H5) (I), Pd2(dba)3 (II), Pd(OAc)2 (III), and [Pd(η3-1-Ph-C3H4)Cl]2 (IV) are frequently utilized as catalyst precursors for a variety of cross-coupling processes, including Suzuki–Miyaura, Heck–Mizoroki, Sonogashira, and Buchwald–Hartwig reactions. In the preceding paper in this issue, we assess and compare catalyst systems based on I–IV activated with PBut3, XPhos, and/or Mor-Dalphos for the prototypical Buchwald–Hartwig amination reactions of 4-bromo- and 4-chloroanisole with morpholine, noting several apparent incongruities which seem to indicate mechanistic dissimilarities for various reactant/precatalyst combinations. In this paper we investigate by NMR spectroscopy the solution chemistry of I and IV with PBut3, XPhos, and Mor-Dalphos, noting similarities and differences in the respective abilities of these precursor–ligand combinations to generate palladium(0) catalyst systems. We find inter alia that steric requirements prevent Xphos and Mor-Dalphos from forming 2:1 palladium(0) complexes and, surprisingly, that 1:1 palladium(0) complexes of Xphos and Mor-Dalphos are unstable with respect to dissociation to free ligand and palladium metal. In other words, these two ligands and, by implication, other sterically demanding phosphine ligands do not form palladium(0) compounds.
A Review of Explantation in 240 Symptomatic Women: A Description of Explantation and Capsulectomy with Reconstruction Using a Periareolar Technique (1998)

A review of 240 women who were explanted is presented. The analysis reviewed physical problems, systemic complaints, and whether explantation relieved symptoms and improved patients. (Plast. Reconstr. Surg. 101: 1364, 1998.)
Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in renal cortex (1978)

An immunohistofluorescence procedure for detecting prostaglandin-forming cyclooxygenase has been used to localize the enzyme in the renal cortex of the cow, guinea pig, rabbit, rat, and sheep. Cyclooxygenase antigenicity was found in endothelial cells lining all arteries and arterioles and in cortical collecting tubules in each species examined. The enzyme was also detected in epithelial cells of Bowman's capsule in the rabbit and in mesangial cells in both ovine and bovine glomerular tufts. That prostaglandins can be formed in renal resistance vessels suggests that it is the synthesis occurring in these vessels which is responsible for the effects of prostaglandins on renal blood flow. Of further note is the correlation that exists between the location of the cyclooxygenase and that of the antidiuretic hormone-responsive adenyl cyclase in the distal nephron.