gebhart/patrepeval huggingface dataset:
Potential role of <scp>anti‐</scp> interleukin‐17 in <scp>COVID</scp> ‐19 treatment (2020)

Dermatologic TherapyVolume 33, Issue 4 e13715 Letter Potential role of anti-interleukin-17 in COVID-19 treatment Erhan Ayhan, Corresponding Author Erhan Ayhan [email protected] orcid.org/0000-0003-1416-2636 Department of Dermatology, University of Health Sciences Gazi Yaşargil Trainning and Research Hospital, Diyarbakır, Turkey Correspondence Erhan Ayhan, Department of Dermatology, University of Health Sciences, Gazi Yaşargil Trainning and Research Hospital, Elazığ Yolu 10. Km Üçkuyular Mevkii 21070 Kayapınar/Diyarbakır, Turkey. Email: [email protected]Search for more papers by this authorMurat Öztürk, Murat Öztürk Department of Dermatology, Van Trainning and Research Hospital, Van, TurkeySearch for more papers by this authorİsa An, İsa An orcid.org/0000-0003-3366-4551 Department of Dermatology, Şanlıurfa Trainning and Research Hospital, Şanlıurfa, TurkeySearch for more papers by this authorAyman Abdelmaksoud, Ayman Abdelmaksoud orcid.org/0000-0003-4848-959X Mansoura Dermatology, Venerology and Leprology Hospital, Mansoura, EgyptSearch for more papers by this authorEşref Araç, Eşref Araç Department of Internal Medicine, University of Health Sciences Gazi Yaşargil Trainning and Research Hospital, Diyarbakır, TurkeySearch for more papers by this author Erhan Ayhan, Corresponding Author Erhan Ayhan [email protected] orcid.org/0000-0003-1416-2636 Department of Dermatology, University of Health Sciences Gazi Yaşargil Trainning and Research Hospital, Diyarbakır, Turkey Correspondence Erhan Ayhan, Department of Dermatology, University of Health Sciences, Gazi Yaşargil Trainning and Research Hospital, Elazığ Yolu 10. Km Üçkuyular Mevkii 21070 Kayapınar/Diyarbakır, Turkey. Email: [email protected]Search for more papers by this authorMurat Öztürk, Murat Öztürk Department of Dermatology, Van Trainning and Research Hospital, Van, TurkeySearch for more papers by this authorİsa An, İsa An orcid.org/0000-0003-3366-4551 Department of Dermatology, Şanlıurfa Trainning and Research Hospital, Şanlıurfa, TurkeySearch for more papers by this authorAyman Abdelmaksoud, Ayman Abdelmaksoud orcid.org/0000-0003-4848-959X Mansoura Dermatology, Venerology and Leprology Hospital, Mansoura, EgyptSearch for more papers by this authorEşref Araç, Eşref Araç Department of Internal Medicine, University of Health Sciences Gazi Yaşargil Trainning and Research Hospital, Diyarbakır, TurkeySearch for more papers by this author First published: 30 May 2020 https://doi.org/10.1111/dth.13715Citations: 6Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article.Citing Literature Volume33, Issue4July/August 2020e13715 RelatedInformation
Interactive edutainment system with enhanced personalized user interface framework (2007)

We present the Responsive Multimedia System, an interactive edutainment system. The system consists of an AR-based tabletop tangible user interface (ARTable) and a virtual environment manager (VEManager) integrated by enhanced Personalized User Interface Framework. In this system, a user interface and virtual environments are integrated seamlessly by sharing user-centric context. To share user-centric context efficiently, our system optimizes the number of network connection between objects in real and virtual environments. The synchronization problem between ARTable and a virtual environment is solved by calculating coordinates with additional information such as collision with terrain and physics law in a virtual environment as well as user-centric context. Moreover, it reorganizes responses of an object according to a user-centric context and condition-action rules. To demonstrate the effectiveness of the proposed system we developed an application on the subject 'Dream of Mee-luck'. According to the experimental results, we found that the proposed system could be a promising technology that enables users to experience an interactive story. In the future, the proposed system can play an important role in developing interactive applications for edutainment.
Alteration of Thermal Conductivity and Viscosity of Liquid by Dispersing Ultra-Fine Particles. Dispersion of Al2O3, SiO2 and TiO2 Ultra-Fine Particles. (1993)

超微粒子を少量, 液体に分散させることによって, 母液の熱伝導率をどれだけ変えられるかが実験的に試みられた. 超微粒子としてAl2O3, SiO2およびTiO2超微粉末を, 液体として水を用い, 安定な分散系を生成した. 非定常細線加熱法で分散系の有効熱伝導率を測定し, 超微粒子の種類, 粒子濃度, 温度による熱伝導率の変化傾向を明らかにした. またそれら分散媒体の粘性率も測定し, その増加傾向を検討した.
Virtually Healthy: Chronic Disease Management in the Home (2002)

Beginning in April 2000, eight clinical demonstration projects were funded for 2 years within the Sunshine Network of the Veterans Health Administration (VHA) to test disease management principles, the care coordinator role, and the effective use of technology to maintain veterans in their homes. Five of these projects focused on complex medical/chronic disease populations. Seven hundred and ninety-one veterans were recruited in these five projects and enrolled in the Community Care Coordination Service (CCCS). The program was conceptualized around and designed by network field staff as an "aging in place" model. The purpose behind the integration of the care coordinator role with technology was to improve health status, increase program efficiency, and decrease resource utilization. Evaluation results to date have shown a 40% reduction in emergency room visits, 63% reduction in hospital admissions, 60% reduction in hospital bed days of care, 64% reduction in VHA nursing home admissions, and 88% reduction in nursing home bed days of care. All Performance Improvement outcomes reached or exceeded the targeted goals, and a functional assessment revealed five significant improvements out of 10 domains of the SF 36V.
Lift/Drag Ratios of Optimised Slewed Elliptic Wings at Supersonic Speeds (1961)

Summary Previous work by R. T. Jones on the drag minimisation of elliptic wings is extended to the case of the slewed wing with thickness. These results are used to calculate lift/drag ratios of idealised configurations related to a supersonic transport aircraft. The values of lift/drag ratio and optimum slenderness ratio found are comparable with those calculated earlier in studies of delta-like plan forms.
Directing Group Assisted Nucleophilic Substitution of Propargylic Alcohols via <i>o</i>-Quinone Methide Intermediates: Brønsted Acid Catalyzed, Highly Enantio- and Diastereoselective Synthesis of 7-Alkynyl-12a-acetamido-Substituted Benzoxanthenes (2015)

BINOL-based, chiral phosphoric acids catalyze the substitution of 1-(o-hydroxyphenyl)propargylic alcohols with enamides to furnish 7-alkynyl-12a-acetamido-substituted benzo[c]xanthenes and related heterocycles in a one-pot operation with excellent diastereo- and enantioselectivity. Ambient reaction temperature, operationally simple reaction conditions, low catalyst loading, high yields, and excellent stereocontrol are attractive features of this process and make it a highly practical and versatile transformation.
Cryopreservation of single‐donor platelets with a reduced dimethyl sulfoxide concentration by the addition of second‐messenger effectors: enhanced retention of in vitro functional activity (1998)

The use of this platelet storage solution in the cryopreservation of platelets yields a significant improvement in their postthaw in vitro recovery and allows for a reduction of the DMSO concentration from 6 to 2 percent, with superior maintenance of in vitro viability and function.
Multiplierless implementations of adaptive FIR filters (2004)

Implementations of adaptive filters using field programmable gate arrays require the ability to change the coefficient values of the filter based on the adaptation algorithm. Multiplierless filter designs rely on a priori knowledge of the coefficient values to implement the filter using hard-wired shifts and additions. We describe a multiplierless approach to adaptive filter implementation that reduces the complexity from quadratic to linear in the number of bits.
Graphene-Based Antibacterial Paper (2010)

Graphene is a monolayer of tightly packed carbon atoms that possesses many interesting properties and has numerous exciting applications. In this work, we report the antibacterial activity of two water-dispersible graphene derivatives, graphene oxide (GO) and reduced graphene oxide (rGO) nanosheets. Such graphene-based nanomaterials can effectively inhibit the growth of E. coli bacteria while showing minimal cytotoxicity. We have also demonstrated that macroscopic freestanding GO and rGO paper can be conveniently fabricated from their suspension via simple vacuum filtration. Given the superior antibacterial effect of GO and the fact that GO can be mass-produced and easily processed to make freestanding and flexible paper with low cost, we expect this new carbon nanomaterial may find important environmental and clinical applications.
OBSERVATIONS ON THE OXIDATION-REDUCTION PROPERTIES OF STERILE BACTERIOLOGICAL MEDIA (1929)

Sterile plain broth contains an active oxidation-reduction system, the characteristics of which have been analyzed. 1. Intensity factor: Under vaseline seal, the lot of broth used in these experiments reaches a reduction potential corresponding to reduced indigo disulfonate (rH = 10). All the indicators with a more positive E(0)' are reduced, the others are not affected. It seems probable that fresh broth, which has not undergone oxidation by molecular oxygen, would give a higher reduction potential. 2. Capacity factor: The maximum amounts of different indicators that can be reduced correspond to equimolecular concentrations. This seems to indicate either (a) that the broth does not contain several "independent" reducing systems (at least in appreciable amounts), or (b) that these hypothetical "independent" systems all have about the same reduction potential. 3. Time factor: The different indicators of oxidation-reduction potentials are reduced in the order of the electromotive series. 4. Nature of the system: The system seems to be reversible (this not excluding the possibility of irreversible autoxidations) and does not appear to be of the nature of a sugar. The relation of these phenomena to the cultivation of different species of bacteria will be reported later.
O-012 (2012)

Pedersen, Marie; Schoket, Bernadette; Godschalk, Roger; Mendez, Michelle A; Knudsen, Lisbeth E; Gutzkow, Kristine B; Fleming, Sarah; Chatzi, Leda; Agramunt, Silvia; Anna, Lívia; Kovács, Katalin; Lukács, Viktória; Merlo, Domenico F; Kleinjans, Jos C; Segerbäck, Dan; Kogevinas, Manolis on behalf of the NewGeneris study group (EU Contract no. FOOD-CT-2005-016320) Author Information
Gut Microbiota Composition Modifies Fecal Metabolic Profiles in Mice (2013)

The gut microbiome is known to be extensively involved in human health and disease. In order to reveal the metabolic relationship between host and microbiome, we monitored recovery of the gut microbiota composition and fecal profiles of mice after gentamicin and/or ceftriaxone treatments. This was performed by employing (1)H nuclear magnetic resonance (NMR)-based metabonomics and denaturing gradient gel electrophoresis (DGGE) fingerprint of gut microbiota. The common features of fecal metabolites postantibiotic treatment include decreased levels of short chain fatty acids (SCFAs), amino acids and primary bile acids and increased oligosaccharides, d-pinitol, choline and secondary bile acids (deoxycholic acid). This suggests suppressed bacterial fermentation, protein degradation and enhanced gut microbial modification of bile acids. Barnesiella, Prevotella, and Alistipes levels were shown to decrease as a result of the antibiotic treatment, whereas levels of Bacteroides, Enterococcus and Erysipelotrichaceae incertae sedis, and Mycoplasma increased after gentamicin and ceftriaxone treatment. In addition, there was a strong correlation between fecal profiles and levels of Bacteroides, Barnesiella, Alistipes and Prevotella. The integration of metabonomics and gut microbiota profiling provides important information on the changes of gut microbiota and their impact on fecal profiles during the recovery after antibiotic treatment. The correlation between gut microbiota and fecal metabolites provides important information on the function of bacteria, which in turn could be important in optimizing therapeutic strategies, and developing potential microbiota-based disease preventions and therapeutic interventions.
Characterization of scattered acoustic intensity fields in the resonance region of a motionless rigid sphere (2010)

In this study, the properties of the scattered acoustic vector fields generated by simple rigid motionless spheres are investigated. Analytical solutions are derived from general acoustic pressure scattering models, and analyzed for wave numbers in the resonance region. The separable active and reactive components of the acoustic intensity are used to investigate the structural features of the scattered field components. Numerical results are presented. The ability to extract scattered field features is illustrated with measurements obtained from a recent in-air experiment using an anechoic chamber and acoustic intensity probes to measure the scattered acoustic vector field from motionless rigid spheres.
Synthesis of Triaxial LiFePO<sub>4</sub> Nanowire with a VGCF Core Column and a Carbon Shell through the Electrospinning Method (2009)

A triaxial LiFePO4 nanowire with a multi wall carbon nanotube (VGCF:Vapor-grown carbon fiber) core column and an outer shell of amorphous carbon was successfully synthesized through the electrospinning method. The carbon nanotube core oriented in the direction of the wire played an important role in the conduction of electrons during the charge-discharge process, whereas the outer amorphous carbon shell suppressed the oxidation of Fe2+. An electrode with uniformly dispersed carbon and active materials was easily fabricated via a single process by heating after the electrospinning method is applied. Mossbauer spectroscopy for the nanowire showed a broadening of the line width, indicating a disordered coordination environment of the Fe ion near the surface. The electrospinning method was proven to be suitable for the fabrication of a triaxial nanostructure.
Corrosion Inhibition of Magnesium Alloys in Coolants (2005)

A number of magnesium alloys show promise as engine block materials. However, corrosion of magnesium alloy engine components by the engine coolant is an important issue in the automotive industry. This paper shows that the corrosion rate of magnesium was increased by dilution and contamination of ethylene glycol. Fortunately, the corrosion of magnesium in ethylene glycol can be effectively inhibited by addition of fluorides. This finding was further verified by assessing the corrosion performance of AZ91D and a recently developed engine block magnesium alloy AM-SC1 in several commercial coolants. Generally speaking, the tested commercial coolants were corrosive to the magnesium alloys in terms of general and galvanic corrosion, but an organic-acid based long-life coolant appeared to be less corrosive than a traditional coolant. It was found that both general and galvanic corrosion rates were significantly decreased by addition of a properly selected inhibitor, and there were no evident side effects on the other engine block materials, such as copper, solder, brass, steel and aluminium alloys, in terms of their corrosion performance. The ASTM D 1384 test further confirmed these results and suggested that a commercial long service life coolant with the inhibitor addition is a promising coolant for magnesium engine blocks.
Quantitative Measurements of Cardiac Phosphorus Metabolites in Coronary Artery Disease by <sup>31</sup> P Magnetic Resonance Spectroscopy (1995)

Compared with healthy control subjects, PCr content decreased significantly in patients with both reversible and fixed 201Tl defects, and ATP content decreased significantly in subjects with fixed thallium defects. These results suggest that the measurement of ATP content in the human heart by 31P MRS is a clinically important method for the evaluation of myocardial viability.
A Simple Solution to a “Blinding” Problem (2002)

R ed–green color blindness is a common condition that affects approximately 2% of the population. Most afflicted people suffer from no problems in their everyday activities. However, in a laboratory setting situations can arise in which the color blind may become disadvantaged. One field in which this may be a distinct problem is in the analysis of histological sections, in particular the assessment of immunohistochemically stained slides. In our laboratory, FITC-conjugated antibodies and propidium iodide counterstaining are used for the detection of myofibroblasts by immunohistochemistry. Interpretation of these images relies on the ability to differentiate between the red and green stains. Both the director and a recently appointed member of staff are red–green color blind and have demonstrated that distinguishing between these colors can be difficult. An obvious approach to solving this problem may be to change the stains and filters used. However, a more cost-effective solution can be found. Digital capture of microscopic images is becoming more common and, in our institute, images are captured for analysis using a microscope-mounted digital camera (Leica DC200). This yields high-quality images that can then be viewed within any common photo editing or graphics package (e.g., Adobe Photoshop, Jasc Paint Shop Pro) for further analysis. Other graphics packages can be used in a similar way. We have found that by manipulating the “hue” of the image, differences between our commonly used stains can be enhanced. The images can be restored to their original form with no data loss by readjusting the hue to its original state. For convenience, a macro has been developed that automatically adjusts the hue of the image before analysis, improving both the speed and accuracy of analysis for the color-blind scientist. This solution requires no additional equipment from that already found in most research institutes and obviates the need to adjust filters or to purchase antibodies with different conjugates/signaling systems. It allows the accurate assessment of a number of images by all laboratory staff.
Design tradeoffs of CMOS current mirrors using one-equation for all-region model (2003)

The design of current mirror involves different conflicting design specifications (noise, bandwidth, input and output resistances, power dissipation, accuracy, THD, etc..), while only three design transistor parameters are available (DC current, width, length). In this paper, we address the effect of such parameters on the current mirror performance. For each specification, an expression is derived which is valid for any inversion level based on the one-equation for all-region MOS model. Experimental results from a current mirror fabricated in 0.5/spl mu/m AMI CMOS process are found in good agreement with the theoretical ones.
A hybrid cache coherence protocol for a decoupled multi-channel optical network: SPEED DMON (2002)

This paper presents a low overhead, high performance cache coherence protocol and an interconnect architecture designed to exploit high bandwidth point-to-point and broadcast features of an optical multi-channel interconnect. SPEED DMON integrates the virtues of snoopy-based schemes and directory-based schemes into a robust hybrid architecture. Directory-assist is used exclusively for decoupled read traffic to eliminate unnecessary broadcasts while snoopy-assist is used exclusively for write and synchronization traffic to reduce directory overhead and synchronization complexities. The proposed scheme has the potential to reduce network latency by up to 85% as a result of its global independence between read and write operations, full concurrency in channel access, reduced link contention, and efficient broadcast of coherence and synchronization events.
Targeted inhibition of osteosarcoma tumor growth by bone marrow‐derived mesenchymal stem cells expressing cytosine deaminase/5‐fluorocytosine in tumor‐bearing mice (2015)

Taken together, these findings suggest that CD/5-FC MSCs may be suitable for targeting human osteosarcoma.
The Assembly of Nonadhesive Fibrinogen Matrices Depends on the αC Regions of the Fibrinogen Molecule (2012)

Adsorption of fibrinogen on fibrin clots and other surfaces strongly reduces integrin-mediated adhesion of platelets and leukocytes with implications for the surface-mediated control of thrombus growth and blood compatibility of biomaterials. The underlying mechanism of this process is surface-induced aggregation of fibrinogen, resulting in the assembly of a nanoscale multilayered matrix. The matrix is extensible, which makes it incapable of transducing strong mechanical forces via cellular integrins, resulting in insufficient intracellular signaling and weak cell adhesion. To determine the mechanism of the multilayer formation, the physical and adhesive properties of fibrinogen matrices prepared from human plasma fibrinogen (hFg), recombinant normal (rFg), and fibrinogen with the truncated αC regions (FgAα251) were compared. Using atomic force microscopy and force spectroscopy, we show that whereas hFg and rFg generated the matrices with a thickness of ∼8 nm consisting of 7-8 molecular layers, the deposition of FgAα251 was terminated at two layers, indicating that the αC regions are essential for the multilayer formation. The extensibility of the matrix prepared from FgAα251 was 2-fold lower than that formed from hFg and rFg. In agreement with previous findings that cell adhesion inversely correlates with the extensibility of the fibrinogen matrix, the less extensible FgAα251 matrix and matrices generated from human fibrinogen variants lacking the αC regions supported sustained adhesion of leukocytes and platelets. The persistent adhesiveness of matrices formed from fibrinogen derivatives without the αC regions may have implications for conditions in which elevated levels of these molecules are found, including vascular pathologies, diabetes, thrombolytic therapy, and dysfibrinogenemia.
Synthesis of sub-200 nm silsesquioxane particles using a modified Stöber sol–gel route (2003)

A range of silsesquioxane nanoparticles has been synthesised by a modified Stöber method. An aqueous sodium silicate solution was used as a seed for further growth of methyl-, ethyl-, phenyl- and vinyl-modified silica spheres. Particles with diameters in the range 60–180 nm were prepared by hydrolysis and condensation reactions of organotrimethoxysilane precursors in a mixture of water, ammonia and ethanol at room temperature. The materials prepared in this study have relatively low specific surface areas and average pore diameters typical of mesoporous solids. The results suggest that the mechanism for the formation of the particles is primarily aggregation and monomer addition.
Correction: Catalytic synthesis of distillate-range ethers and olefins from ethanol through Guerbet coupling and etherification (2019)

Correction for ‘Catalytic synthesis of distillate-range ethers and olefins from ethanol through Guerbet coupling and etherification’ by Nathaniel M. Eagan <italic>et al.</italic>, <italic>Green Chem.</italic>, 2019, <bold>21</bold>, 3300–3318.
Significantly Longer Progression-Free Survival With <i>nab</i>-Paclitaxel Compared With Docetaxel As First-Line Therapy for Metastatic Breast Cancer (2009)

This randomized study in first-line MBC demonstrated superior efficacy and safety of weekly nab-paclitaxel compared with docetaxel, with a statistically and clinically significant prolongation of PFS (> 5 months) in patients receiving nab-paclitaxel 150 mg/m(2) weekly compared with docetaxel 100 mg/m(2) q3w.