gebhart/patrepeval huggingface dataset:
Novel Approaches to Profile Modification in Horizontal Slotted Liners at Prudhoe Bay, Alaska (1997)

Abstract The development of new techniques and materials for performing profile modification treatments in horizontal, uncemented slotted liner completions at Prudhoe Bay, Alaska is reported in this paper. Historically, it has been difficult, if not impossible, to perform remedial profile modification treatments in horizontal slotted liners. The lack of annular isolation and uncertainties with conventional fluid placement posed seemingly insurmountable challenges. The development and field trials of two new techniques that address these problems are presented in this paper. The first approach uses advanced gel technology for fullbore, non-selective treatments for water shut off and selective placement for gas shut off. The second uses a new thixotropic cement slurry to place a chemical packer around the slotted liner for zonal isolation - opening the door for conformance treatments. Certain preliminary successes of these techniques have prevented the need for sidetracking wells to new locations or permanently abandoning zones. This has saved the operating companies significant wellwork expenditures. Treatments have been performed on five wells to date with several more in the development stage. Treatment descriptions, operational rationale, and pre- and post-production trends are presented. The horizontal slotted liner profile modifications performed are all technical successes with 60% of the treatments also economically viable. Even though it is early in the life cycle of these technologies, the successful treatments are encouraging and have opened up a large candidate pool. These new techniques and materials are promising options allowing remedial work in horizontal wells with uncemented slotted liners.
Properties of Heat-Reactive Oil-Soluble Phenolic Resins - Effect of Compostion and pH (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProperties of Heat-Reactive Oil-Soluble Phenolic Resins - Effect of Compostion and pH R. H. RunkCite this: Ind. Eng. Chem. 1950, 42, 10, 2110–2114Publication Date (Print):October 1, 1950Publication History Published online1 May 2002Published inissue 1 October 1950https://pubs.acs.org/doi/10.1021/ie50490a029https://doi.org/10.1021/ie50490a029research-articleACS PublicationsRequest reuse permissionsArticle Views64Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Food security and health risks facing vulnerable youth in north-west Tasmania (2013)

Aims: Food security is determined by several interrelated factors—including food available, food access and food utilisation—all of which have a direct influence on health outcomes. The north-west coast of Tasmania has in recent years faced a number of socioeconomic challenges resulting from the loss of industry and infrastructure. Vulnerable and marginalised communities, including young unemployed people, have been significantly impacted by the economic downturn. The study examined the relationship between the socioeconomic environment, food security and the health status of vulnerable young people (18–25 year olds) on the north-west coastal areas of Tasmania.
DNA sequence of the 5′ flanking region of the human interleukin 2 gene: homologies with adult T-cell leukemia virus (1984)

We previously reported the sequence of the gene for human interleukin 2 (IL-2) which included about 220 b.p. of the 5' flanking region. In this report we have extended the 5' sequence to 1263 b.p. before the start site of transcription and have compared the entire sequence of the IL-2 gene and its 5' flanking region with that of Adult T-cell leukemia virus (ATLV). Four regions of limited homology were noted. Three areas of homology to the viral long terminal repeat (LTR) were seen in the 5' sequence flanking IL-2. A fourth region of homology to the viral LTR was located within the second intron of the IL-2 gene. While the significance of these homologies is not known, it is possible that they are involved in regulating the expression of ATLV and IL-2, both of which are generally restricted to T cells.
Cycling of human dendritic cell effector phenotypes in response to TNF‐α: modification of the current ‘maturation’ paradigm and implications for <i>in vivo</i> immunoregulation (1999)

Dendritic cells (DCs) are potent antigen presenting cells reported to undergo irreversible functional 'maturation' in response to inflammatory signals such as TNF-alpha. The current paradigm holds that this DC maturation event is required for full functional capacity and represents terminal differentiation of this cell type, culminating in apoptotic cell death. This provides a possible mechanism for avoiding dysregulated immunostimulatory activity, but imposes constraints on the capacity of DCs to influence subsequent immune responses and to participate in immunological memory. We report that the cell surface and functional effects induced by TNF-alpha are reversible and reinducible. These effects are accompanied by a concordant modulation of cytokine mRNA expression that includes the induction of proinflammatory factors (IL-15, IL-12, LT-alpha, LT-beta, TNF-alpha, RANTES) which is coincident with the down-regulation of counter-regulatory cytokines (IL-10, TGF-beta1, TGF-beta2, IL-1 RA, MCP-1). The resultant net effect is a dendritic cell activation state characterized by a transient proinflammatory posture. These results demonstrate that 1) human DCs do not undergo terminal 'maturation' in response to TNF-alpha, 2) DC phenotypes are more pleiotropic than previously thought, and 3) DCs are potential immunoregulatory effector cells with implications for control of immune responses in both in vivo and in vitro systems.
Frequency synthesis via the discrete chirp and prime sequence ROM's (1976)

Surface-acoustic-wave (SAW) sampled-data filters can be utilized as serial access READ-ONLY memories to directly implement at carrier frequencies a coherent fast-frequency-hop synthesizer in the VHF and UHF ranges. An example of frequency synthesis using surface acoustic wave discrete chirp filters is shown. A frequency synthesis scheme using a SAW prime-sequence filter is described.
Antimicrobial photodynamic therapy treatment of chronic recurrent sinusitis biofilms (2011)

aPDT can effectively treat CRS polymicrobial antibiotic-resistant bacteria, fungi, and biofilms in vivo. Human clinical studies are currently planned to assess the safety and efficacy of this treatment for CRS.
Loss of Angiotensin-Converting Enzyme 2 Accelerates Maladaptive Left Ventricular Remodeling in Response to Myocardial Infarction (2009)

We conclude that loss of ACE2 facilitates adverse post-MI ventricular remodeling by potentiation of Ang II effects by means of the AT1 receptors, and supplementing ACE2 can be a potential therapy for ischemic heart disease.
Higher Order Blind Separation Of Non Zero-Mean Cyclostationary Sources (2002)

Publication in the conference proceedings of EUSIPCO, Toulouse, France, 2002
Complementary distributions of vinculin and dystrophin define two distinct sarcolemma domains in smooth muscle. (1993)

The sarcolemma of the smooth muscle cell displays two alternating structural domains in the electron microscope: densely-staining plaques that correspond to the adherens junctions and intervening uncoated regions which are rich in membrane invaginations, or caveolae. The adherens junctions serve as membrane anchorage sites for the actin cytoskeleton and are typically marked by antibodies to vinculin. We show here by immunofluorescence and immunoelectron microscopy that dystrophin is specifically localized in the caveolae-rich domains of the smooth muscle sarcolemma, together with the caveolae-associated molecule caveolin. Additional labeling experiments revealed that beta 1 integrin and fibronectin are confined to the adherens junctions, as indicated by their codistribution with vinculin and tensin. Laminin, on the other hand, is distributed around the entire cell perimeter. The sarcolemma of the smooth muscle cell is thus divided into two distinct domains, featuring different and mutually exclusive components. This simple bipartite domain organization contrasts with the more complex organization of the skeletal muscle sarcolemma: smooth muscle thus offers itself as a useful system for localizing, among other components, potential interacting partners of dystrophin.
Evaluation of assay methods to measure plasma ADAMTS13 activity in thrombotic microangiopathies (2010)

Evaluation of assay methods to measure plasma ADAMTS13 activity in thrombotic microangiopathies -
The Stability of 100 ppb Hydrogen Sulfide Standards (2004)

An experimental study has been performed to determine the factors affecting the stability of hydrogen sulfide calibration mixtures at concentrations below 1 ppm. Quantitative data was obtained that illustrates that material selection and surface treatment are major factors affecting the shelf life of low concentration reactive gas mixtures. With the proper material selection and surface treatment, hydrogen sulfide and carbonyl sulfide standard mixtures on the order of 50-100 ppb can be maintained for at least 18 months.
Effects of icosapent ethyl on lipid and inflammatory parameters in patients with diabetes mellitus-2, residual elevated triglycerides (200–500 mg/dL), and on statin therapy at LDL-C goal: the ANCHOR study (2013)

Clinicaltrials.gov Identifier NCT01047501.
Effects of melatonin on microtubule assembly depend on hormone concentration: Role of melatonin as a calmodulin antagonist (1994)

Melatonin may play a key role in cytoskeletal rearrangements through its calmodulin antagonism. In the present work, we tested this hypothesis by studying melatonin effects on both microtubule polymerization in vitro and cytoskeletons in situ. Microtubule assembly is a dynamic process inhibited by Ca2+/calmodulin. Calmodulin antagonists prevent the inhibition by binding to Ca(2+)-activated calmodulin, thus causing microtubule enlargement. In the presence of calmodulin (5 microM) and CaCl2 (1 mM), polymerization at equilibrium was inhibited by 40%. Complete reversal of the Ca2+/calmodulin effect on microtubules was observed with 10(-9) M melatonin or with 10(-5) M trifluoperazine or 1 microgram/ml of compound 48/80. In the absence of Ca2+/calmodulin, melatonin at 10(-5) M inhibited tubulin polymerization like 10(-4) M trifluoperazine does. Melatonin effects on microtubule assembly at both nanomolar and micromolar ranges were corroborated in cytoskeletons in situ. Therefore, it is suggested that at a low concentration (10(-9) M), cytoskeletal melatonin effects are mediated by its antagonism to Ca2+/calmodulin. At a higher concentration (10(-5) M), non-specific binding of melatonin to tubulin occurs, thus overcoming the melatonin antagonism to Ca2+/calmodulin. The results support the hypothesis that under physiological conditions, melatonin synchronizes different body rhythms through cytoskeletal rearrangements mediated by its calmodulin antagonism.
Photocatalytic Carbon‐Nanotube–TiO<sub>2</sub> Composites (2009)

Abstract The literature and advances in photocatalysis based on the combination of titania (TiO 2 ) and carbon nanotubes is presented. The semiconductor basis for photocatalysis is introduced for anatase and rutile. Furthermore, the proposed mechanisms of catalytic enhancement resulting from the pairing of the titania semiconductor with either metallic, semiconducting, or defect‐rich carbon nanotubes (CNT) is discussed. Differences are apparent for the mixtures and chemically bonded CNT–TiO 2 composites. The article then highlights the recent advances in the synthesis techniques for these composites and their photocatalytic reactions with organic, inorganic, and biological agents. Finally, various applications and challenges for these composite materials are reported.
Inhibition by magnesium and calcium acetates of lead subacetate- and nickel acetate-induced lung tumors in strain A mice. (1984)

The ability of the physiologically essential divalent metals calcium and magnesium to inhibit the tumorigenic activities of lead and nickel towards the lungs of strain A mice was investigated. The tumorigenic salts lead(II) subacetate and nickel(II) acetate were injected i.p. at their maximal tolerated doses (0.04 mmol/kg/injection of each metal) for a total of 24 injections, whenever possible. Calcium(II) acetate and magnesium(II) acetate were administered in the same preparation along with the lead and nickel salts at molar doses of approximately 1, 3, 10, and 30 times the maximal tolerated dose of the tumorigen. The animals were sacrificed 30 weeks after the first injection, and the lung tumors were counted. The lead and nickel salts, administered alone, each produced a significant increase in the observed number of lung adenomas per mouse. When administered with any of the doses of calcium acetate or magnesium acetate tested, neither lead subacetate nor nickel acetate showed any significant tumorigenic activity. Calcium acetate alone (total dose, 11 mmol/kg of body weight) appeared to yield a significant rise in lung adenomas observed. The results indicate an antagonism between magnesium and calcium and the tumorigenic metals nickel and lead.
Xenon in intensive care * (2003)

Copyright © by 2003 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
Down-regulation of the β-chemokine receptor CCR6 in dendritic cells mediated by TNF-α and IL-4 (1999)

Chemokines are involved in the control of dendritic cell (DC) trafficking, which is critical for the immune response. We have generated DC from human umbilical cord blood CD34+ progenitors cultured with granulocyte-macrophage colony-stimulating factor, tumor necrosis factor alpha (TNF-alpha), and stem cell factor. Using an anti-CCR6 monoclonal antibody, we observed that these cells showed maximum expression of this beta-chemokine receptor when they were immature, as determined by their relatively low expression of several DC maturation markers such as CD1a, CD11c, CD14, CD40, CD80, and CD83. Immature DC responded strongly to macrophage inflammatory protein-3alpha (MIP-3alpha), the CCR6 ligand, in migration and calcium mobilization assays. CCR6 expression decreased in parallel with the DC maturation induced by prolonged TNF-alphaq treatments. Interleukin-4 was also able to decrease CCR6 protein levels. Our findings suggest that the MIP-3alpha/CCR6 interaction plays an important role in the trafficking of immature DC to chemokine production sites such as injured or inflamed peripheral tissues, where DC undergo maturation on contact with antigens.
Conjugated polymers for organic LED`s: Poly[2,5-bis(-3A-5{beta}-cholestanoxy)-phenylenevinylene] (BCHA-PPV): A processable, yellow light emitter (1993)

The authors report on the preparation and characterization of the title polymer and its photoluminescence as well as electroluminescence. The polymer was prepared in good yield with a molecular {approximately}10{sup 8} vs poly(styrene). The cholestanoxy groups were attached to the monomer precursor via a Mitsunobu coupling. The PPV was obtained by the typical p-xylylene intermediate route.
Synthesizing a new dielectric elastomer exhibiting large actuation strain and suppressed electromechanical instability without prestretching (2012)

Abstract Prestrain provides high actuation performance in dielectric elastomers (DEs) but increases the bulk, mass, and fatigue of the resulting actuators. Based on our experiments on prestrain‐locked interpenetrating polymer films and the model developed by Zhao and Suo, materials with a certain stress–strain relationship should be capable of high strain without prestrain by suppressing electromechanical instability (EMI). Here, we report the synthesis of an acrylic elastomer capable of achieving high actuation performance without prestrain. DE films were directly fabricated by ultraviolet curing of precursors comprising a mixture of acrylate comonomers. Varying the amount of crosslinker comonomer in the precursor allowed us to tune the stress–strain relationship and completely suppress EMI while maintaining high strain performance. Addition of plasticizing agents increased strain sensitivity. The result is a new DE, synthesized from scratch, capable of high actuation strain (>100%), high energy density (>1 J g −1 ), and good temperature and frequency response without requiring prestretching. The material can be fabricated using conventional coating techniques and the process can allow for high volume throughput of stacked DE actuators. © 2012 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2013
Two-dimensional control of surface plasmons and directional beaming from arrays of subwavelength apertures (2004)

We demonstrate two-dimensional control of coherent modes of surface plasmons (SP) in a metallic array of subwavelength apertures. SP mode intensity and propagation direction is manipulated by varying the wavelength, incidence angle, and polarization of the excitation photons. We also demonstrate directional beaming of light from this device. Finite-difference-time-domain simulations of the SP modes closely resemble the observations by near-field scanning optical microscopy. Calculated SP coupling efficiencies and transmission are also presented.
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca <sup>2+</sup> store depletion (2007)

Stromal interaction molecule 1 (STIM1) has recently been identified by our group and others as an endoplasmic reticulum (ER) Ca(2+) sensor that responds to ER Ca(2+) store depletion and activates Ca(2+) channels in the plasma membrane (PM). The molecular mechanism by which STIM1 transduces signals from the ER lumen to the PM is not yet understood. Here we developed a live-cell FRET approach and show that STIM1 forms oligomers within 5 s after Ca(2+) store depletion. These oligomers rapidly dissociated when ER Ca(2+) stores were refilled. We further show that STIM1 formed oligomers before its translocation within the ER network to ER-PM junctions. A mutant STIM1 lacking the C-terminal polybasic PM-targeting motif oligomerized after Ca(2+) store depletion but failed to form puncta at ER-PM junctions. Using fluorescence recovery after photobleaching measurements to monitor STIM1 mobility, we show that STIM1 oligomers translocate on average only 2 mum to reach ER-PM junctions, arguing that STIM1 ER-to-PM signaling is a local process that is suitable for generating cytosolic Ca(2+) gradients. Together, our live-cell measurements dissect the STIM1 ER-to-PM signaling relay into four sequential steps: (i) dissociation of Ca(2+), (ii) rapid oligomerization, (iii) spatially restricted translocation to nearby ER-PM junctions, and (iv) activation of PM Ca(2+) channels.
A 1-to-2.5GHz phased-array IC based on g<inf>m</inf>-RC all-pass time-delay cells (2012)

Electronically variable delays for beamforming are generally realized by phase shifters. Although a constant phase shift can approximate a time delay in a limited frequency band, this does not hold for larger arrays that scan over wide angles and have a large instantaneous bandwidth. In this case true time delays are wanted to avoid effects such as beam-squinting. In this paper we aim at compactly integrating a delay based phased-array receiver in standard CMOS IC technology. This is for instance relevant for synthetic aperture radars, which require large instantaneous bandwidths often in excess of 1GHz, either as RF or as IF bandwidth in a superheterodyne system. We target low-GHz radar frequencies, assuming sub-arrays of four elements and up to 550ps delay.
<title>Temporal and spatial projection onto the convex set (POCS) based error concealment algorithm for the MPEG-encoded video sequence</title> (1995)

The paper presents an algorithm attempting to combine both intra-frame and interframe information to reconstruct lost macroblocks due to imperfect communication channels when decoding a MPEG bitstream. The algorithm is a POCS-based (Projection Onto the Convex Set) iterative restoration algorithm incorporating both the temporal and spatial constraints derived from a set of analysis performed on the picture sequence. Often the use of the temporal information in the restoration process is complicated by the scene changes or large random motion activities. To reliably utilize the temporal information, we formulate a series of test to determine the usefulness of the temporal information. In addition, the tests yield a temporal constraint if the temporal information is deemed good. Along with the spatial constraints as described in [1], the temporal constraint is used in the proposed iterative restoration algorithm.
A New Elastomeric Suspension Spring (1971)

<div class="htmlview paragraph">This paper describes a constant natural frequency spherical elastomeric spring element. The concept of constant natural frequency and its advantage in providing consistent ride quality with varying vehicle weight is reviewed.</div> <div class="htmlview paragraph">Performance data on the spherical spring for both laboratory and field tests is presented and evaluated.</div>
Voltage balancing method for IGBTs connected in series (2003)

This paper presents a new method to balance the voltages of the series connected IGBTs. This method can be realized only by adding simple circuits to the gate drive system of the IGBTs, and its effect of balancing the IGBT's collector-Emitter voltages during the switching transients is remarkable. Principal of this strategy and experimental results with series connected two IGBTs are described firstly. After that, further experimental results are set forth, which are switching tests with four 2.5 kV flat-packaged IGBTs connected in series. Through the switching tests, superior characteristics of the proposed method have been confirmed.
Polypropylene Ligatures as a Means of Controlling Intraocular Pressure with Molteno Implants (1989)

A technique for controlling intraocular pressure in the immediate postoperative period with Molteno implants is described. Filtration tubes were closed with polypropylene sutures in 13 patients. Filtration tubes closed with 7-0 sutures provided the most satisfactory partial to complete lumen closure. The ligatures in six patients later were opened by argon laser.
Polytetrafluoroethylene Characterized by XPS, with Monochromatic Al Source (1993)

Polytetrafluorethylene (PTFE) is a technologically important material employed for broad applications due to its exceptional properties for lubrication, insulation, and chemical inertness. With regard to surface analysis, PTFE has been found to provide a ready standard source for the x-ray photoelectron F 1s line in a polymeric matrix. A previous submission [M. Ackeret, Surf. Sci. Spectra 1, 100 (1992)] examined the uniformity of the atomic composition over the surface layers by angle dependent XPS analysis of the C 1s and F 1s lines. In this submission we wish to present a compilation of the photoelectron, Auger, and valence band transitions excited by monochromatic Al x-ray radiation.