gebhart/patrepeval huggingface dataset:
Ultra-low delay for all (2016)

This demo dramatically illustrates how replacing 'Classic' TCP congestion control (Reno, Cubic, etc.) with a 'Scalable' alternative like Data Centre TCP (DCTCP) keeps queuing delay ultra-low; not just for a select few light applications like voice or gaming, but even when a variety of interactive applications all heavily load the same (emulated) Internet access. DCTCP has so far been confined to data centres because it is too aggressive---it starves Classic TCP flows. To allow DCTCP to be exploited on the public Internet, we developed DualQ Coupled Active Queue Management (AQM), which allows the two TCP types to safely co-exist. Visitors can test all these claims. As well as running Web-based apps, they can pan and zoom a panoramic video of a football stadium on a touch-screen, and experience how their personalized HD scene seems to stick to their finger, even though it is encoded on the fly on servers accessed via an emulated delay, representing 'the cloud'. A pair of VR goggles can be used at the same time, making a similar point. The demo provides a dashboard so that visitors can not only experience the interactivity of each application live, but they can also quantify it via a wide range of performance stats, updated live. It also includes controls so visitors can configure different TCP variants, AQMs, network parameters and background loads and immediately test the effect.
A hierarchical mobility management scheme for IPv6 (2002)

As the number of portable devices roaming across the Internet increases, the problem of routing packets to mobile hosts generates increasing research and commercial interest. This paper presents a hierarchical scheme to support mobility in the Internet. This scheme is based on the multicast routing protocol PIM-SM. In this proposal, a mobile node is seen by its correspondent nodes as a special multicast group. Packets destined for a mobile host are delivered to its RP (rendezvous point) and then forwarded to the mobile node's current location. Our scheme has two main benefits. First, it is hierarchical and therefore reduces handoff latency and the load on the Internet. Second, it uses IP multicast and consequently benefits from its diffusion property, which can be very useful for providing smooth subnet handoffs. We compare the performance of our approach with the IETF Mobile IPv6 proposal. We show that while our approach has a larger memory space requirement, it reduces the network load, provides smoother and faster subnet handoffs and frees the mobile hosts from mobility support procedures.
Planar reconfigurable antenna with integrated switching control circuitry (2014)

In this paper we propose a pattern reconfigurable planar antenna with integrated control circuitry, for flexible applications with Software Defined Radio (SDR) platforms. The antenna's layout is made by four folded microstrip elements placed symmetrically on a low cost FR-4 substrate. By using PIN diodes, the metallic elements can be switched to generate a single omnidirectional beam or six directional beams around the azimuth plane. The design includes MOSFET based control circuitry for switching the PIN diodes. The RF performance has been experimentally evaluated under different levels of control voltage. The radiation of omnidirectional and directional beams along with an integrated control board, allows for convenient utilization of the antenna in numerous SDR MIMO platforms.
APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore (2019)

Our study illuminates important differences in the molecular behavior of APOL1 nonrisk and risk variants, and our observations suggest a mechanism that may explain the very different functional effects of these variants, despite the lack of consistently observed differences in trafficking patterns, intracellular localization, or binding partners. Variant-dependent differences in oligomerization pattern may underlie APOL1's recessive, gain-of-function biology.
Oral Glucose Tolerance Test among adolescents with impaired Fasting Blood Glucose (2015)

Background: Type 2 Diabetes Mellitus (DM) is emerging as a major health problem even amongst children and adolescents. The onset is usually preceded by period of impaired glucose metabolism known as Impaired Fasting Glucose (IFG) and or Impaired Glucose Tolerance (IGT). This study is aimed at determining the presence of impaired glucose tolerance in adolescents aged 10 to 19 years with impaired fasting glucose. Methodology: Oral glucose tolerance test was done for a cohort of 68 adolescents aged 10 to 19 years with impaired fasting blood glucose detected at a school screening. Age, sex, anthropometric measures (height, weight, BMI and BMI percentiles were determined using appropriate methods. Blood pressure and family history of DM was determined. IGT was determined as a two hour post glucose load blood glucose value of > 7.8mmol/l and < II.1mmol/l. Result: The mean age of the subjects was 15.08 ± 2.03 years. There were 23 (33.8%) males and 45 (66.2%) females, giving a male to female ratio of 1:2. Thirteen (19.1%) were overweight/obese, 16 (23.5%) had family history of diabetes mellitus and 17(25%) had hypertension. Seven (10.3%) of the subjects had impaired glucose tolerance and no case of diabetes. The mean BMI and fasting blood glucose value was higher in subjects with impaired glucose tolerance compared to those without. There was no statistically significant difference in prevalence of hypertension, overweight/obesity and hypertension in the two groups with or without impaired glucose tolerance. Conclusion: There was no concordance in occurrence of IFG and IGT. Mean fasting blood glucose and mean BMI was higher in those with both IFG and IGT. Screening for only IGT will therefore miss subjects with IFG.
A lifetime prediction method for hot-carrier degradation in surface-channel p-MOS devices (1990)

Hot carrier degradation of p-MOS devices at low gate voltages (V/sub g/<V/sub d/) is examined. It is shown that the electronic gate current is the principal factor in stress damage in this gate voltage range and that the damage itself consists of trapped electrons, localized close to the drain junction. The saturation of the transconductance change as a function of time which is seen at long stress times of high stress voltages results from a change in the injected gate current as a function of time. This is caused by changes in electric field in the silicon due to charge trapping in the oxide during stress. The saturation effect can, however, be transformed into a simple power law if the time axis is multiplied by the square of the instantaneous gate current. This allows for the development of a lifetime-prediction method. The method is applied to 1.0- mu m p-MOS devices, and a lifetime is estimated.<<ETX>>
Novel Microwave Microfluidic Sensor Using a Microstrip Split-Ring Resonator (2014)

In this paper, a new type of microwave microfluidic sensor is proposed to detect and determine the dielectric properties of common liquids. The technique is based on perturbation theory, in which the resonant frequency and quality factor of the microwave resonator depend on the dielectric properties of the resonator. A microstrip split-ring resonator with two gaps is adopted for the design of the sensors (i.e., a double split-ring resonator). This resonator is both compact and planar, making it suitable for a lab-on-a-chip approach. Several types of solvents are tested with two types of capillaries to verify sensor performance. At 3 GHz, very good agreement is demonstrated between simulated and measured results.
Clathration of Hard-to-Separate Aromatic Mixtures with New Werner Complexes (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTClathration of Hard-to-Separate Aromatic Mixtures with New Werner ComplexesPierre de Radzitzky and Jacques HanotierCite this: Ind. Eng. Chem. Process Des. Dev. 1962, 1, 1, 10–14Publication Date (Print):January 1, 1962Publication History Published online1 May 2002Published inissue 1 January 1962https://pubs.acs.org/doi/10.1021/i260001a002https://doi.org/10.1021/i260001a002research-articleACS PublicationsRequest reuse permissionsArticle Views193Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Defensins – innate immunity at the epithelial frontier (2001)

Physical barrier function was formerly believed to play the major role in mucosal protection against luminal bacteria. This view has now been challenged by the discovery of specialized molecules that possess antimicrobial activity. More than 100 peptides have been identified so far, and the number is still growing. These peptides are distributed widely and conserved throughout phylogeny. The epithelial expression of antimicrobial peptides is of particular interest as many pathogens adhere to epithelial surfaces and may eventually invade the host. This rapidly acting defence system of innate immunity is already engaged before adoptive immune interactions take place. These antimicrobial peptides consist of constitutive and inducible forms, potentiating this barrier function in terms of an inflammatory response. One important subgroup of antimicrobial peptides is the family of defensins, which are classified as alpha (alpha-) and beta (beta-) defensins. Eight different peptides with varying antimicrobial properties have been identified. They are distributed widely in humans, and organ-specific expression patterns have been observed. Homologous peptides have been found in other mammals, vertebrates, invertebrates, insects and plants. The identification of alpha-defensins and their murine counterparts, cryptdins, in the small intestine prompted intensive research into epithelial antimicrobial defence.
Repression of the high‐methionine zein gene in the maize inbred line Mo17 (1993)

Summary The methionine content in maize kernels is largely determined by the level of a methionine‐rich 10 kDa protein, encoded by the gene Zps10/(22) . In the maize inbred BSSS53 this gene is over‐expressed compared with its normal expression in inbred lines like W64A and W22. This is in part due to the trans ‐acting factor Zpr10/(22) . However, compared with the normal level of expression, this gene is under‐expressed in the inbred Mo17 and the high‐methionine zein accumulates to very low levels. Therefore, differential expression of this gene between BSSS53 and Mo17 is even larger than in other inbred lines of maize. Repression of 10 kDa zein expression in Mo17 is not due to the translatability of 10 kDa zein mRNA or a cis ‐acting mutation in the mRNA and neither is it due to a change in the transcription rate per se . However, steady state levels of mRNA appear to be controlled in trans by narrowing the developmental time frame of mRNA accumulation.
Model statement of criteria and procedures for appointment, promotion in academic rank, and tenure for college and university librarians (1987)

Model statement of criteria and procedures for appointment, promotion in academic rank, and tenure for college and university librarians
Cytophotometric Study of Deoxyribonucleic Acid in Cortisone-Treated Rat Hepatocytes (1959)

Rats were treated by intramuscular injection with cortisone acetate, 25 mg./day for 5 days. Small pieces of liver obtained from treated and normal animals were squashed on a microscope slide so as to obtain many areas only a single cell in thickness. After Feulgen staining to demonstrate DNA, optical density was measured using a projection technique. In both the normal and treated animals the nuclei were easily segregated in three ploidy classes, diploid, tetraploid, and octaploid, depending upon Feulgen intensity. In all three classes, the absorbence of nuclei from cortisone-treated animals was approximately 20 per cent lower than the normal. These data were interpreted to indicate that a change in DNA content had been induced by cortisone administration. These findings are comparable to data obtained from similar animals using chemical methods for the determination of DNA.
Travel medicine (1995)

This review discusses certain recent developments in the field of travel medicine. New vaccines for hepatitis A, typhoid fever, and cholera are discussed, as well as pertinent vaccine-related issues with diphtheria in the former Soviet Union, polio in Latin America, and meningococcal meningitis worldwide. Malaria prophylaxis and treatment recommendations are discussed. Issues of imported onchocerciasis, recent outbreaks of plague in India and schistosomiasis in Lake Malawi, and cases of Japanese encephalitis and melioidosis in travelers are reviewed.
A more efficient and optimal LLR for decoding and verification (1999)

We propose a new confidence score for decoding and verification. Since the traditional log likelihood ratio (LLR) is borrowed from speaker verification technique, it may not be appropriate for decoding because we do not have a good modelling and definition of LLR for decoding/utterance verification. We have proposed a new formulation of LLR that can be used for decoding and verification task. Experimental results show that our proposed LLR can perform equally well compared with the result based on maximum likelihood in a decoding task. Also, we get an 5% improvement in decoding compared with traditional LLR.
Shakespeare In Washington, D. C. (1978)

Journal Article Shakespeare In Washington, D. C. Get access Jeanne Addison Roberts Jeanne Addison Roberts The American University Search for other works by this author on: Oxford Academic Google Scholar Shakespeare Quarterly, Volume 29, Issue 2, Spring 1978, Pages 234–238, https://doi.org/10.2307/2869113 Published: 01 April 1978
Automatic Doping of Polyaniline with Organic Electron Acceptors (1991)

Abstract Complexes of polyaniline (PANI) with various organic π-electron acceptors such as benzoquinones were prepared by the automatic doping method. Relation of their electrical, electrochemical and spectroscopic properties to the strength in electron affinity of the acceptors were revealed.
Organization of the Mammalian Locomotor CPG: Review of Computational Model and Circuit Architectures Based on Genetically Identified Spinal Interneurons (2015)

The organization of neural circuits that form the locomotor central pattern generator (CPG) and provide flexor-extensor and left-right coordination of neuronal activity remains largely unknown. However, significant progress has been made in the molecular/genetic identification of several types of spinal interneurons, including V0 (V0D and V0V subtypes), V1, V2a, V2b, V3, and Shox2, among others. The possible functional roles of these interneurons can be suggested from changes in the locomotor pattern generated in mutant mice lacking particular neuron types. Computational modeling of spinal circuits may complement these studies by bringing together data from different experimental studies and proposing the possible connectivity of these interneurons that may define rhythm generation, flexor-extensor interactions on each side of the cord, and commissural interactions between left and right circuits. This review focuses on the analysis of potential architectures of spinal circuits that can reproduce recent results and suggest common explanations for a series of experimental data on genetically identified spinal interneurons, including the consequences of their genetic ablation, and provides important insights into the organization of the spinal CPG and neural control of locomotion.
Structures and Electrical Properties of Ag–Tetracyanoquinodimethane Organometallic Nanowires (2005)

Ag-tetracyanoquinodimethane (Ag-TCNQ) nanostructures are synthesized using both solution reaction in acetonitrile and a novel vacuum-saturated vapor reaction method. Experiments show that the latter synthesis method produces Ag-TCNQ nanowires with better uniformity and higher aspect ratio. These nanowires, having diameters around 100 nm and lengths about 5 /spl mu/m, could serve as potential building blocks of nanoscale electronics. Nanodevices based on these nanowires are fabricated using the electron-beam lithography technique. Electrical transport study shows reproducible I--V hysteresis with a change in resistance of four orders of magnitude, demonstrating electrical memory effect. This electrical bistability makes Ag-TCNQ nanowires a promising candidate for future applications in ultrahigh-density information storage.
Comparative morphometric analysis of age-related changes in the pyramidal neurons of the human prefrontal and posterior associative cortex from birth to 7 years (2022)

Aim: This article is devoted to the study of age-related changes in the body volume of pyramidal neurons (VP) of the human prefrontal (PFC) and posterior associative cortex (PAC) in children from birth to 7 years of age. Methods: The material consisted of left cerebral hemispheres obtained from 60 male individuals. We studied the areas 8, 45 and 10 in the PFC and area 37 in subareas 37ac, 37a, 37d in the PAC. For morphometry of pyramidal neurons in cortical sublayer III3, we used virtual images of serial frontal paraffin sections of cortex 10 thick stained by Nissl. We determined the mean value of VP (mean VP), the standard error of the mean, and the confidence interval for each age group. Results: The most significant changes in the mean VP in all studied cortical areas occurred during the first 6 months of life. The greatest increase in the VP was detected in the PFC from 3.5 to 7 years, and in the PAC from 1.5 to 3 years of age. There are close positive correlations between agerelated changes in the size of neurons in the PFC and in the PAC. Conclusion: In children, the development of pyramidal neurons of the external pyramidal plate in the PAC occurs earlier and at a more intensive pace compared to the PFC. We suggest that VP is an important quantitative indicator that allows us to assess the timing and rate of age-related structural changes in the cerebral cortex.
Inhibition of STAT3 signaling prevents vascular smooth muscle cell proliferation and neointima formation (2012)

Dedifferentiation, migration, and proliferation of resident vascular smooth muscle cells (SMCs) are key components of neointima formation after vascular injury. Activation of signal transducer and activator of transcription-3 (STAT3) is suggested to be critically involved in this process, but the complex regulation of STAT3-dependent genes and the functional significance of inhibiting this pathway during the development of vascular proliferative diseases remain elusive. In this study, we demonstrate that STAT3 was activated in neointimal lesions following wire-induced injury in mice. Phosphorylation of STAT3 induced trans-activation of cyclin D1 and survivin in SMCs in vitro and in neointimal cells in vivo, thus promoting proliferation and migration of SMCs as well as reducing apoptotic cell death. WP1066, a highly potent inhibitor of STAT3 signaling, abrogated phosphorylation of STAT3 and dose-dependently inhibited the functional effects of activated STAT3 in stimulated SMCs. The local application of WP1066 via a thermosensitive pluronic F-127 gel around the dilated arteries significantly inhibited proliferation of neointimal cells and decreased the neointimal lesion size at 3 weeks after injury. Even though WP1066 application attenuated the injury-induced up-regulation of the chemokine RANTES at 6 h after injury, there was no significant effect on the accumulation of circulating cells at 1 week after injury. In conclusion, these data identify STAT3 as a key molecule for the proliferative response of SMC and neointima formation. Moreover, inhibition of STAT3 by the potent and specific compound WP1066 might represent a novel and attractive approach for the local treatment of vascular proliferative diseases.
A conductive polymer pressure sensor (1988)

The authors have characterized the performance of the commercially available Interlink pressure sensor. The sensor costs less than $1. It is 0.25-mm thick, is light and flexible, and can be customized for a wider range of applications. The resistance-versus-pressure characteristic of the sensor is logarithmic. The operating range is from 0 to 2 MPa. The hysteresis is 8% and the nonrepeatability is less than 7% of full scale. The temperature drift is -0.5%/ degrees C of full scale. Using the Interlink sensors and electronics, the authors developed a portable data acquisition system to monitor the pressure under the bony prominences of the feet during normal gait. The advantages and drawbacks of the sensor are indicated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Quantitative analysis of the trapping effect on terahertz AlGaN/GaN resonant tunneling diode (2011)

We report on a simulation for terahertz aluminum gallium nitride (AlGaN)/gallium nitride (GaN) resonant tunneling diode (RTD) at room temperature by introducing deep-level defects into the polarized AlGaN/GaN/AlGaN quantum well. Results show that an evident degradation in negative-differential-resistance characteristic of RTD occurs when the defect density is higher than ∼106 cm−2, which is consistent with the measurements of the state-of-the-art GaN RTDs. At around 300 GHz, the simulation for a RTD oscillator also demonstrates evident decreases of rf power and efficiency because of the electron trapping effect.
Conjugation of Monoclonal Antibodies with TETA Using Activated Esters: Biological Comparison of <sup>64</sup> Cu-TETA-1A3 with <sup>64</sup> Cu-BAT-2IT-1A3 (2001)

A simple method for conjugation of monoclonal antibodies (mAbs) with the chelating agent 1,4,8,11-tetraazacyclotetradecane-1,4,8,11-tetraacetic acid (TETA), has been developed using commercially available reagents. This method involved activation of a single carboxyl group of TETA with N-hydroxysulfosuccinimide and 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide. The resulting activated ester of TETA was reacted with the anti-colorectal carcinoma mAb 1A3 at molar ratios ranging from 10:1 to 100:1 to give immunoconjugates modified with an average of 0.4 to 2.0 functional chelators per antibody molecule. The TETA-1A3 conjugate was labeled with 64Cu at specific activities as high as 15.4 microCi/microgram, and the radiolabeled mAb exhibited high in vitro serum stability and minimal loss of immunoreactivity. The biodistribution of 64Cu-labeled TETA-1A3 in hamsters bearing GW39 human colon carcinoma xenografts was compared to that of 64Cu-BAT-2IT-1A3 (BAT = 6-(p-bromoacetamidobenzyl)-1,4,8,11-tetraazacyclotetradecane-1,4,8,11- tetraacetic acid; 2IT = 2-iminothiolane). Both conjugates showed high tumor uptake (6.60-9.05% injected dose/gram) from 24 to 48 h post-injection and generally similar blood clearance and non-target organ uptakes. Human absorbed dose estimates derived from the hamster biodistribution data showed the critical organs for both conjugates to be the large intestine and the red marrow. Our results suggest that the in vitro and in vivo performance characteristics of 64Cu-TETA-1A3 compare favorably with those of 64Cu-BAT-2IT-1A3 and that further evaluation of the diagnostic and therapeutic efficacy of 64Cu-TETA-1A3 is warranted.