gebhart/patrepeval huggingface dataset:
Optical Millimeter-Wave Generation and Transmission Without Carrier Suppression for Single- and Multi-Band Wireless Over Fiber Applications (2010)

A new optical millimeter-wave generation scheme to double the beating frequency without suppressing the carrier by taking advantages of the out-of-phase property between sidebands of a phase-modulated optical carrier is proposed for the first time. Theoretical analysis shows that the generated 60 GHz optical millimeter-wave (mm-wave) can tolerant ±0.016 nm wavelength drifting with filter bandwidth ranging from 70 to 100 GHz to sustain first to second harmonic suppression ratio of 18 dB. The doubled frequency is continuously tunable from 60 to 90 GHz within 100 GHz filter bandwidth with RF power variation of less than 2 dB. In addition, simultaneously generating and transmitting multi-band signal: millimeter-wave band, microwave band, and baseband leveraging the same concept is also proposed. Error-free transmission of 2.5 Gb/s wireless baseband signals carried by the generated 60 GHz mm-wave is successfully demonstrated in both single- and multi-band network environments over a combined optical fiber and wireless distance with a proper equivalent isotropically radiated power of about 20 dBm for in-building access. Moreover, dispersion effect on the generated frequency-doubled optical mm-wave is analyzed by experimentally comparing the link performance of both single mode fiber (SMF-28) and dispersion-shifted fiber cases. It is concluded that for single-band service delivery, the proposed scheme is immune to the interference from the dispersion-induced, redundant 1st harmonics; however, to deliver multi-band services, launching lightwave at zero-dispersion wavelength over SMF-28 is highly recommended to mitigate inter-band interference.
Preparation of Polymer−Silicon(100) Hybrids via Interface-Initiated Reversible Addition-Fragmentation Chain-Transfer (RAFT) Polymerization (2006)

10.1021/ma0607362
Nickel-catalyzed conjugate addition of alkenylzirconium species to .alpha.,.beta.-unsaturated ketones (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNickel-catalyzed conjugate addition of alkenylzirconium species to .alpha.,.beta.-unsaturated ketonesJeffrey Schwartz, Melanie J. Loots, and Hiroshi KosugiCite this: J. Am. Chem. Soc. 1980, 102, 4, 1333–1340Publication Date (Print):February 1, 1980Publication History Published online1 May 2002Published inissue 1 February 1980https://pubs.acs.org/doi/10.1021/ja00524a017https://doi.org/10.1021/ja00524a017research-articleACS PublicationsRequest reuse permissionsArticle Views795Altmetric-Citations109LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Status of flash (2012)

FLASH, the FEL user facility at DESY, is operated with an electron beam energy up to 1 GeV corresponding to a photon wavelength down to 6.5 nm. The shutdown in summer 2007 was followed by a three month commissioning and study period. A new run of FEL experiments started in November 2007. The full year 2008 is dedicated to beam operation: about half of the time is scheduled for FEL users, and the rest for accelerator and FEL physics studies. Here we report the present status of FLASH as an FEL user facility.
660. Beckmann'sche Umlagerung durch Benzolsulfonsäurechlorid bei Gegenwart von Alkali oder Pyridin (1904)

i i i alkalischer Liisung erfolgender Umlagernngen unsere Kenntnisse Gber das Wesen der ~B e c k m a n n ' s c h e n Reactiona.zu erweitern.Es bat sich dabei ergehen, dass bei der Umlagerung mit Benzolsulfonsiurechlorid in alltalischer Liisung oft andere Producte entstehen ale n saurer, und ferner, dass sich die Umlagerung mit Benzolsulfonaiiurechlorid nicht nur in alkalischer, sondern auch in Pyridinliisung vollzieht.I n letzterem Falle
Adaptive lattice filters for narrowband interference rejection in DS spread spectrum systems (2002)

In the presence of narrowband interference, the performance of direct sequence (DS) spread spectrum communication systems can be improved by using various types of interference rejection filters. The performance of a DS spread spectrum receiver employing a lattice filter for interference rejection is analysed. The filter parameters are adjusted using the stochastic gradient lattice algorithm. For ease of analysis, the adaptive lattice filter is modelled as an optimal Wiener filter followed by an additive misadjustment noise. Analytical expressions for the reflection coefficients and general expressions for the minimum mean square error and the variance of the misadjustment noise are presented. An expression for the system bit error rare, which takes into account, the filter misadjustment noise is derived and numerical results are presented.
metastable level density and temperature measurement in a low-density argon plasma (1997)

Temperature and density measurements of the 4s(3)P(2) argon metastable atom level in a weakly diffusion ionized argon plasma are presented and discussed. The steady state collisionless unmagnetized plasma is generated at a gas pressure of 50 mPa, extruded by hot filament DC discharges and diffused in a chamber of about 40 \\ volume. The temperature is measured from the absorption linewidth and the density from the spectral absorption coefficient of a low-cost single-mode diode laser (801 479 nm) by scanning its frequency around the 4s(3)P(2)-4p(3)D(2) Arl transition.
Phase 1 Dose-Ranging Safety Trial of Lactobacillus crispatus CTV-05 for the Prevention of Bacterial Vaginosis (2009)

All 3 dose levels of LACTIN-V appeared to be safe and acceptable in healthy volunteers.
CCR5 and CXCR4 Expression on Memory and Naive T Cells in HIV-1 Infection and Response to Highly Active Antiretroviral Therapy (2001)

CCR5 elevation is a concomitant of immune activation and viral replication that occurs in HIV-1 infection, but the relation of CXCR4 depression to severity of infection, disease progression, and response to therapy remains undefined.
Fundamentals of Risk Management: Understanding, Evaluating and Implementing Effective Risk Management (2010)

Now more than ever, organizations must plan, response and recognize all forms of risks that they face. "Fundamentals of Risk Management", now in its second edition, provides a comprehensive introduction to the subject of commercial and business risk for anyone studying for a career in risk as well as a broad range of risk professionals. It examines the key components of risk management and its application with examples to demonstrate its benefit to organisations in the public and private sector. The second edition has been completely updated to take into account the greater influence of ISO 3100, the emergence of Governance Risk and Compliance (GRC) and the wide use of the bowtie method to illustrate risk management. In addition, there is now a chapter on the skills and competencies required by an effective risk manager.
Synthesis and insecticidal activity of 3‐(haloalkyl‐1,3‐dienyl)‐2,2‐dimethylcyclopropanecarboxylates (1986)

Abstract New 2,2‐dimethylcyclopropanecarboxylic acids bearing halogenated 1,3‐alkadienyl substituents at position 3 of the cyclopropane ring were synthesised and the insecticidial activities of their 3‐phenoxybenzyl and α‐cyano‐3‐phenoxybenzyl esters against housefly ( Musca domestica ), Colorado potato beetle ( Leptinotarsa decemlineata ) and Egyptian cotton leafworm ( Spodoptera littoralis ) were determined. The activity of these compounds varied according to the relative position of the halogen substituents on the diene chain. The observed changes of activity with the structure of the side chain are discussed in terms of the coplanarity of the conjugated double bonds.
Syntax, preference, and right attachment (1985)

The paper claims that the right attachment rules for phrases originally suggested by Frazier and Fodor are wrong, and that none of the subsequent patchings of the rules by syntactic methods have improved the situation. For each rule there are perfectly straightforward and indefinitely large classes of simple counterexamples. We then examine suggestions by Ford et al., Schubert and Hirst which are quasi-semantic in nature and which we consider ingenious but unsatisfactory. We offer a straightforward solution within the framework of preference semantics, and argue that the principal issue is not the type and nature of information required to get appropriate phrase attachments, but the issue of where to store the information and with what processes to apply it. We present a prolog implementation of a best first algorithm covering the data and contrast it with closely related ones, all of which are based on the preferences of nouns and prepositions, as well as verbs.
Tantalizing Transcriptomes--SAGE and Its Use in Global Gene Expression Analysis (1999)

Victor Velculescu, the winner of this year's Pharmacia Biotech & Science Prize for Young Scientists, discusses his doctoral research on the development of SAGE (serial analysis of gene expression) and its application to unraveling the differences in gene expression between normal cells and tumor cells.
A Model Study on the Effect of an Amino Group on the Antioxidant Activity of Glutathione Peroxidase (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Model Study on the Effect of an Amino Group on the Antioxidant Activity of Glutathione PeroxidaseMichio Iwaoka and Shuji TomodaCite this: J. Am. Chem. Soc. 1994, 116, 6, 2557–2561Publication Date (Print):March 1, 1994Publication History Published online1 May 2002Published inissue 1 March 1994https://pubs.acs.org/doi/10.1021/ja00085a040https://doi.org/10.1021/ja00085a040research-articleACS PublicationsRequest reuse permissionsArticle Views1143Altmetric-Citations300LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
ChemInform Abstract: The First Synthesis of a C‐9 Carbonyl Modified Baccatin III Derivative and Its Conversion to Novel Taxol and Taxotere Analogues. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Mechanism of autophosphorylation of the multifunctional Ca2+/calmodulin-dependent protein kinase. (1985)

The multifunctional Ca2+/calmodulin-dependent protein kinase purified from rat brain cytosol undergoes a self-phosphorylation or autophosphorylation reaction. Our conclusion that this reaction is autocatalytic is based on the following lines of evidence: The autophosphorylation reaction and the protein kinase activity toward other substrates are absolutely dependent on the presence of both Ca2+ and calmodulin; autophosphorylation and phosvitin kinase activity show a similar time course and indistinguishable heat lability; the reaction is a consistent property of every preparation of rat brain kinase; the reaction is present in both crude and highly purified preparations of similar kinases or isozymes from rat lung, spleen, heart, bovine brain, and a neuronal tissue from Aplysia californica, a marine mollusk; phosphorylation of the kinase subunits is not mimicked by addition of cAMP, cGMP, Ca2+ plus diglyceride, or addition of the cAMP-dependent protein kinase, and is not blocked by the heat-stable inhibitor protein of the cAMP-dependent protein kinase; and the reaction is intramolecular. Autophosphorylation results in the stoichiometric incorporation of phosphate into both the 51,000- and 60,000-dalton subunits.
Bone Matrix-induced Local Bone Induction (1985)

The sequential cellular changes in the implants in response to collagenous bone matrix-induced local bone formation include: binding of fibronectin to matrix, chemotaxis and attachment of progenitor cells, proliferation and differentiation of progenitor cells into chondrocytes, and finally osteogenesis and marrow differentiation. The cellular origin of osteogenic proteins is not clear. The present study compares the osteogenic potential of demineralized rat and porcine bone matrix by dissociative extraction and reconstitution. Judging from the Sephacryl S-200 gel filtration profiles of the dissociative extracts of rat and porcine matrix, the latter appears to be smaller. Under identical experimental conditions, the rat chondrosarcoma and osteosarcoma were examined for chondrogenic and osteogenic properties and found to be devoid of inductive potential. It is noteworthy that gel filtration fractions of rat chondrosarcoma on Sepharose CL-6B are inhibitory to bone inductive potential of demineralized rat bone matrix.
Exploiting the Expressiveness of Cyclo-Static Dataflow to Model Multimedia Implementations (2007)

The design of increasingly complex and concurrent multimedia systems requires a description at a higher abstraction level. Using an appropriate model of computation helps to reason about the system and enables design time analysis methods. The nature of multimedia processing matches in many cases well with cyclo-static dataflow (CSDF), making it a suitable model. However, channels in an implementation often use for cost reasons a kind of shared buffer that cannot be directly described in CSDF. This paper shows how such implementation specific aspects can be expressed in CSDF without the need for extensions. Consequently, the CSDF graph remains completely analyzable and allows reasoning about its temporal behavior. The obtained relation between model and implementation enables a buffer capacity analysis on the model while assuring the throughput of the final implementation. The capabilities of the approach are demonstrated by analyzing the temporal behavior of an MPEG-4 video encoder with a CSDF graph.
Immobilization strategies for small molecule, peptide and protein microarrays (2009)

Protein, peptide and small molecule microarrays are valuable tools in biological research. In the last decade, substantial progress has been achieved to make these powerful technologies more reliable and available for researchers. This review describes chemical preparation methods for these microarrays with focus on site-selective and bioorthogonal immobilization reactions, particularly the Staudinger ligation and the thiol-ene reaction. In addition, the application of peptide microarrays, which were prepared by Staudinger ligation, to substrate specificity mapping is illustrated.
In vitro synthesis of cellulose II from a cytoplasmic membrane fraction of Acetobacter xylinum (1987)

The cytoplasmic and outer membranes of Acetobacter xylinum (ATCC 53582) were isolated by discontinuous sucrose density ultracentrifugation. Both lysozyme (EC 3.2.1.17) and trypsin (EC 3.4.21.4) were required for efficient crude membrane separation. Primary dehydrogenases and NADH oxidase were used as cytoplasmic membrane markers, and 2-keto-3-deoxyoctulosonic acid was used to identify the outer membranes. Cellulose synthetase (UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase; EC 2.4.1.12) activity was assayed as the conversion of radioactivity from UDP-[(14)C]glucose into an alkali-insoluble beta-1,4-D-[(14)C]glucan. This activity was predominantly found in the cytoplasmic membrane. The cellulose nature of the product was demonstrated by (i) enzymatic hydrolysis followed by TLC, (ii) methylation analysis followed by TLC, and (iii) GC/MS. Further, the weight-average and number-average degree of polymerization of the in vitro product, determined by high-performance gel permeation chromatography, were 4820 and 5270, respectively. In addition, x-ray diffraction analysis indicated that the in vitro product is cellulose II, which is in contrast to the in vivo product-namely, cellulose I.
Analysis of Accretion and Deletion at Boundaries in Dynamic Scenes (1985)

In dynamic scenes, the presence of object boundaries is often signaled by the appearance or disappearance of occluded surfaces over time. Such regions of surface accretion or deletion can be found using matching techniques similar to those used to determine optical flow in an image sequence. Regions in one frame that are not adequately matched by any region in previous frames correspond to accretion. Regions that have no matches in subsequent frames correspond to deletion. In either case, an occlusion boundary is present. Furthermore, by associating accretion or deletion regions with a surface on one side of a boundary, it is possible to determine which side of the boundary is being occluded. This association can be based purely on visual motion-the accretion or deletion region moves with the same image velocity as the remaining visible surface to which it is attached.
Syntaxin 6 functions in trans-Golgi network vesicle trafficking. (1997)

The specific transfer of vesicles between organelles is critical in generating and maintaining the organization of membrane compartments within cells. Syntaxin 6 is a recently discovered member of the syntaxin family, whose constituents are required components of several vesicle trafficking pathways. To better understand the function of syntaxin 6, we generated a panel of monoclonal antibodies that specifically recognize different epitopes of the protein. Immunoelectron microscopy shows syntaxin 6 primarily on the trans-Golgi network (TGN), where is partially colocalizes with the TGN adapter protein AP-1 on clathrin-coated membranes. Additional label is present on small vesicles in the vicinity of endosome-like structures. Immunoprecipitation of syntaxin 6 revealed that it is present in a complex or complexes with alpha-soluble NSF attachment protein, vesicle-associated membrane protein 2, or cellubrevin and a mammalian homologue of VPS45, which is a member of the sec1 family implicated in Golgi to prevacuolar compartment trafficking in yeast. We show that mammalian VPS45 is found in multiple tissues, is partially membrane associated, and is enriched in the Golgi region. Converging lines of evidence suggest that syntaxin 6 mediates a TGN trafficking event, perhaps targeting to endosomes in mammalian cells.
Fighting Tumor Cell Survival: Advances in the Design and Evaluation of Pim Inhibitors (2010)

The Pim (provirus insertion site of Moloney murine leukemia virus) family of serine/threonine protein kinases possesses the fundamental characteristics critical for the biology of eukaryotes, in particular, survival and malignant transformation of cells. The members of this protein family (Pim-1 to Pim-3) are aberrantly expressed in human tumors, most frequently in prostate cancer and hematological malignancies. Therefore, Pim proteins are widely considered as attractive targets in cancer chemotherapy. Growing knowledge of mechanisms of Pim-mediated anti-apoptosis and transformation, as well as rapid progress in the design of Pim-modulating compounds dictate the need for an in-depth analysis of the chemistry of inhibitors and the modes of their interaction with these protein kinases. This review summarizes recent advances in understanding the molecular events regulated by Pim proteins. In addition, we focus on the non-patent literature (mostly since 2005) that demonstrates a diversity of chemical classes of small molecular weight Pim inhibitors. The X-ray co-crystal structures of complexes Pim:inhibitor provide evidence for SAR data important for the choice of synthetic routes, optimization of lead compounds and testing chemical libraries. We also discuss a cell-based test system useful for rapid and inexpensive pre-screening of compounds capable of preventing Pim-mediated phosphorylation.
Synthetic scleral reinforcement materials. II. Collagen types in the fibrous capsule (1996)

Attainment of a steady state in fibrous-capsule formation around a polymeric implant is indicative of minimization of the foreign-body response, and is characterized by thin capsule walls, few macrophages, and the replacement of type III collagen with type I collagen within the capsular matrix. We implanted four general types of extraocular band materials (porous, solid, composite, and patched) in rabbit eyes, and examined the proportions of types III and I collagen in the surrounding fibrous-capsule walls at intervals after surgery. Immunohistochemical analysis showed that 18 months after implantation of the band materials, the capsules adjacent to the porous-material surfaces had virtually no type III collagen remaining, while the solid-surface-material capsules still contained more than trace amounts (greater than 5%). In that the bands were implanted around the outside of the globe, which provides a dynamic environment in constant motion, it may be that the cellular ingrowth permitted by the porous materials increased the stability of the implants, thereby lessening the foreign body response and allowing the collagen replacement characteristic of the steady state to be completed. In contrast the solid-surface implants, which had little cellular ingrowth, may have continued to undergo sufficient micromovement within the capsule walls to sustain a low-level activation of the wound-healing response, resulting in thicker capsule walls and residual type III collagen a year and a half after implantation surgery.
A second generation survey AUV (2002)

Odyssey class autonomous underwater vehicles (AUVs) are designed to be small, high performance survey platforms. The logistical complexities of operating off of oceanographic vessels or in hostile environments, such as the Arctic, make a small vehicle with minimal support requirements extremely attractive. Although built for great depths and endurances of up to two days, Odyssey class vehicles are small by the standards of existing AUVs. This paper describes Odyssey II, the second generation of Odyssey class AUV, and presents the results of under-ice field trials in New Hampshire and the Arctic.