gebhart/patrepeval huggingface dataset:
Charge-domain sampling of high-frequency signals with embedded filtering (2006)

Subsampling can be used in a radio receiver to perform signal downconversion and sample-and-hold operations in order to relieve the operation frequency and bandwidth requirements of the subsequent discrete-time circuitry. However, due to the inherent aliasing behaviour of wideband noise and interference in subsampling, and the difficulty of implementing appropriate bandpass anti-aliasing filtering at high frequencies, straightforward use of a low subsampling rate can result in significant degradation of the receiver dynamic range. The aim of this thesis is to investigate and implement methods for integrating filtering into high-frequency signal sampling and downconversion by subsampling to alleviate the requirements for additional front-end filters and to mitigate the effects of noise and out-of-band signal aliasing, thereby facilitating use in integrated high-quality radio receivers. The charge-domain sampling technique studied here allows simple integration of both continuous-and discrete-time filtering functions into high-frequency signal sampling. Gated current integration results in a lowpass sin(x)/x(sinc(x)) response capable of performing built-in anti-aliasing filtering in baseband signal sampling. Weighted integration of several successive current samples can be further used to obtain an embedded discrete-time finite-impulse-response (FIR) filtering response, which can be used for internal anti-aliasing and image-rejection filtering in the downconversion of bandpass signals by subsampling. The detailed analysis of elementary charge-domain sampling circuits presented here shows that the use of integrated FIR filtering with subsampling allows acceptable noise figures to be achieved and can provide effective internal anti-aliasing rejection. The new methods for increasing the selectivity of elementary charge-domain sampling circuits presented here enable the integration of advanced, digitally programmable FIR filtering functions into high-frequency signal sampling, thereby markedly relieving the requirements for additional antialiasing, image rejection and possibly even channel selection filters in a radio receiver. BiCMOS and CMOS IF sampler implementations are presented in order to demonstrate the feasibility of the charge-domain sampling technique for integrated anti-aliasing and image-rejection filtering in IF signal quadrature downconversion by subsampling. Circuit measurements show that this sampling technique for built-in filtering results in an accurate frequency response and allows the use of high subsampling ratios while still achieving a competitive dynamic range.
Natural convection immersion cooling of an array of simulated chips in an enclosure filled with dielectric liquid (1987)

http://archive.org/details/naturalconvectio1094522377
An Improved Two-factor Authentication Protocol (2010)

Most recently, Yang et al proposed a new set of security requirements for two-factor smart-card-based password mutual authentication and then suggested a new scheme satisfying all their security requirements. In this paper, however, we first show one critical security weakness being overlooked, i.e., allowing key-compromise impersonation. We provide an attack to illustrate the adversary is able to masquerade any user to access the server's service in their protocol once if the long-term key of the server is compromised. Thereafter, we suggests key-compromise impersonation resilience should be added as one more important security requirement for two-factor smart-card based password mutual authentication and then propose an improved protocol to eliminate the security weakness existing in Yang et al's protocol.
Vibrating RF MEMS overview: applications to wireless communications (2005)

Micromechanical RF filters and reference oscillators based on recently demonstrated vibrating on-chip micromechani-cal resonators with Q's >10,000 at 1.5 GHz, are described as an attractive solution to the increasing count of RF components (e.g., filters) expected to be needed by future multi-band wireless devices. With Q's this high in on-chip abun-dance, such devices might also enable a paradigm-shift in transceiver design where the advantages of high-Q are emphasized, rather than suppressed, resulting in enhanced robustness and power savings. An overview of the latest in vi-brating RF MEMS technology is presented with an addendum on remaining issues to be addressed for insertion into tomorrow's handsets.
Signals and noise in magnetotellurics (1985)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1985Signals and noise in magnetotelluricsAuthors: E. A. NicholsH. F. MorrisonJ. ClarkeE. A. NicholsUniv. of California, Berkeley, H. F. MorrisonUniv. of California, Berkeley, and J. ClarkeUniv. of California, Berkeleyhttps://doi.org/10.1190/1.1892691 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetailsCited BySome aspects of magnetotelluric field procedures8 July 2005 | Surveys in Geophysics, Vol. 9, No. 3-4 SEG Technical Program Expanded Abstracts 1985ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1985 Pages: 643 publication data© 1985 Copyright © 1985 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 07 Mar 2005 CITATION INFORMATION E. A. Nichols, H. F. Morrison, and J. Clarke, (1985), "Signals and noise in magnetotellurics," SEG Technical Program Expanded Abstracts : 259-261. https://doi.org/10.1190/1.1892691 Plain-Language Summary PDF DownloadLoading ...
An Access Control Model for NoSQL Databases (2013)

Current development platforms are web scale, unlike recent platforms which were just network scale. There has been a rapid evolution in computing paradigm that has created the need for data storage as agile and scalable as the applications they support. Relational databases with their joins and locks influence performance in web scale systems negatively. Thus, various types of non-relational databases have emerged in recent years, commonly referred to as NoSQL databases. To fulfill the gaps created by their relational counter-part, they trade consistency and security for performance and scalability. With NoSQL databases being adopted by an increasing number of organizations, the provision of security for them has become a growing concern.\nThis research presents a context based abstract model by extending traditional role based access control for access control in NoSQL databases. The said model evaluates and executes security policies which contain versatile access conditions against the dynamic nature of data. The goal is to devise a mechanism for a forward looking, assertive yet flexible security feature to regulate access to data in the database system that is devoid of rigid structures and consistency, namely a document based database such as MongoDB.
Chemical Protein Synthesis Using a Second-Generation <i>N</i>-Acylurea Linker for the Preparation of Peptide-Thioester Precursors (2015)

The broad utility of native chemical ligation (NCL) in protein synthesis has fostered a search for methods that enable the efficient synthesis of C-terminal peptide-thioesters, key intermediates in NCL. We have developed an N-acylurea (Nbz) approach for the synthesis of thioester peptide precursors that efficiently undergo thiol exchange yielding thioester peptides and subsequently NCL reaction. However, the synthesis of some glycine-rich sequences revealed limitations, such as diacylated products that can not be converted into N-acylurea peptides. Here, we introduce a new N-acylurea linker bearing an o-amino(methyl)aniline (MeDbz) moiety that enables in a more robust peptide chain assembly. The generality of the approach is illustrated by the synthesis of a pentaglycine sequence under different coupling conditions including microwave heating at coupling temperatures up to 90 C, affording the unique and desired N-acyl-N'-methylacylurea (MeNbz) product. Further extension of the method allowed the synthesis of all 20 natural amino acids and their NCL reactions. The kinetic analysis of the ligations using model peptides shows the MeNbz peptide rapidly converts to arylthioesters that are efficient at NCL. Finally, we show that the new MeDbz linker can be applied to the synthesis of cysteine-rich proteins such the cyclotides Kalata B1 and MCoTI-II through a one cyclization/folding step in the ligation/folding buffer.
Oxide Catalysts for Rechargeable High‐Capacity Li–O<sub>2</sub> Batteries (2012)

Abstract Nano‐crystalline mixed metal oxides with an expanded pyrochlore structure are synthesized by a chemical precipitation route in alkaline media. The high concentration of surface active sites afforded by their high surface area, intrinsically variable oxidation state and good electron transport lead to promising electrocatalytic properties for oxygen evolution in Li‐O 2 cells, yielding rechargeable discharge capacities over 10 000 mAh g −1 and lowering anodic overpotentials significantly. The discharge capacity of the Li‐O 2 cell is increased further when a small amount of gold is deposited on the pyrochlore oxide, which serves as a more efficient oxygen reduction catalyst. The amount of catalyst necessary for oxygen evolution performance is reduced to as little as 5 wt% by supporting the highly‐divided pyrochlore oxide crystallites on carbon using in‐situ deposition methods.
Pulsed optoacoustic characterization of layered media (2000)

Thermoelastic waves generated by absorption of short laser pulses are used to characterize the layer structure of materials. The method is based on the analysis of the distribution of absorbed laser energy from temporal profiles of recorded acoustic signals. Particularly in view of noninvasive medical applications, optoacoustic front surface transducers are investigated in this study, where irradiation of the surface and detection of the acoustic wave take place on the same side of the sample. Front surface detection of optoacoustic waves is studied theoretically and experimentally, with special emphasis on acoustic diffraction and the differences between measurements in the acoustic near and far field. In the experiments, samples with stepwise and continuously varying depth profiles of absorption coefficient were irradiated with laser pulses of 6–8 ns duration. For the detection of the acoustic waves either an optical ultrasound sensor or an annular piezoelectric film was used. Generating the optoacoustic waves with a flat top laser beam profile and detecting the signals in the acoustic near field yields optimal conditions for direct measurements of the distribution of absorbed energy and the absorption coefficient in the medium. Far field measurements are advantageous for detecting and imaging layer boundaries at large depths in the sample.
1,2,4-Triazole amino nucleosides. 1-.beta.-D-3'-amino-3'-deoxyribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides (1977)

The synthesis of 1-beta-D-3'-amino-3'-deoxyribofuranosyl-1,2,4-triazole-3-carboxamide--the 3'-amino analogue of ribavirin--and five related nucleoside analogues is described. Each analogue exhibited LD50 concentrations greater than 100 microgram/mL against P-388 mouse lymphoid leukemia cells in tissue culture. Antiviral testing indicated that none of the compounds exhibited significant activity.
Wearable Solar Cells by Stacking Textile Electrodes (2014)

A new and general method to produce flexible, wearable dye-sensitized solar cell (DSC) textiles by the stacking of two textile electrodes has been developed. A metal-textile electrode that was made from micrometer-sized metal wires was used as a working electrode, while the textile counter electrode was woven from highly aligned carbon nanotube fibers with high mechanical strengths and electrical conductivities. The resulting DSC textile exhibited a high energy conversion efficiency that was well maintained under bending. Compared with the woven DSC textiles that are based on wire-shaped devices, this stacked DSC textile unexpectedly exhibited a unique deformation from a rectangle to a parallelogram, which is highly desired in portable electronics. This lightweight and wearable stacked DSC textile is superior to conventional planar DSCs because the energy conversion efficiency of the stacked DSC textile was independent of the angle of incident light.
A new technique to assess insulin sensitivity in humans: the rapid insulin sensitivity test (RIST). (2007)

The objective of this study was to develop a Rapid Insulin Sensitivity Test (RIST) in humans, a test already used in animal studies. Insulin sensitivity was assessed using a rapid modified euglycemic clamp, the RIST. In this test, glucose disposition was determined after an intravenous (i.v.) bolus (50mU/kg bw administered over 30 seconds) of insulin, before and after feeding a standardized test meal, in healthy male subjects (aged 27.8 +/- 2.4 years, BMI 23.5 +/- 1.2 kg/m2). The RIST uses as the index of insulin sensitivity, the total amount of glucose required to be infused to maintain euglycemia during insulin action following an i.v. bolus of insulin. During the RIST, glucose levels are determined at 2-min intervals in order to clamp the glycemia at baseline values. Following a 24 hr fasting period, the RIST index was 225.6 +/- 25.1 mg glucose/kg bw. The volunteers were then fed a standardized test meal, a new stable glucose level was obtained 100 min after the meal, and a second RIST was performed. The glucose requirement (RIST index) increased to 647.9 +/- 73.5 mg glucose/kg bw following the standardized test meal (n = 5, p < 0.001). This report describes a new technique to evaluate insulin sensitivity in healthy humans. The RIST is a powerful research tool to assess the glucose utilization action of an insulin bolus in fasted and fed states both evaluated in the same day.
C--: A portable assembly language (1998)

. Of late it has become very common for research compilers to emit C as their target code, relying on a C compiler to generate machine code. In effect, C is being used as a portable compiler target language. It offers a simple and effective way of avoiding the need to re-implement effective register allocation, instruction selection, and instruction scheduling, and so on, all for a variety of target architectures. The trouble is that C was designed as a programming language not as a compiler target language, and is not very suitable for the latter purpose. The obvious thing to do is to define a language that is designed as a portable target language. This paper describes C--, a portable compiler target language, or assembler. C-- has to strike a balance between being high-level enough to allow the back end a fair crack of the whip, while being low level enough to give the front end the control it needs. It is not clear that a path exists between these two rocks; the ghos...
Skin-brain axis signaling mediates behavioral changes after skin wounding (2021)

Patients with chronic wounds often have associated cognitive dysfunction and depression with an as yet unknown mechanism for this association. To address the possible causality of skin wounding inducing these changes, behavior and cognitive functions of female C57BL/6 mice with an excisional skin wound were compared to unwounded animals. At six days post wounding, animals exhibited anxiety-like behaviors, impaired recognition memory, and impaired coping behavior. Wounded animals also had concomitant increased hippocampal expression of Tnfa, the pattern recognition receptor (PRR) Nod2, the glucocorticoid receptors GR/Nr3c1 and Nr3c2. Prefrontal cortex serotonin and dopamine turnover were increased on day six post-wounding. In contrast to the central nervous system (CNS) findings, day six post -wounding serum catecholamines did not differ between wounded and unwounded animals, nor did levels of the stress hormone corticosterone, TNFα, or TGFβ. Serum IL6 levels were, however elevated in the wounded animals. These findings provide evidence of skin-to-brain signaling, mediated either by elevated serum IL6 or a direct neuronal signaling from the periphery to the CNS, independent of systemic mediators. Wounding in the periphery is associated with an altered expression of inflammatory mediators and PRR genes in the hippocampus, which may be responsible for the observed behavioral deficits.
The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein (2017)

The biological function of α-Synuclein has been related to binding to lipids and membranes but these interactions can also mediate α-Synuclein aggregation, which is associated to Parkinson's disease and other neuropathologies. In brain tissue α-Synuclein is constitutively N-acetylated, a modification that plays an important role in its conformational propensity, lipid and membrane binding, and aggregation propensity. We studied the interactions of the lipid-mimetic SDS with N-acetylated and non-acetylated α-Synuclein, as well as their early-onset Parkinson's disease variants A30P, E46K and A53T. At low SDS/protein ratios α-Synuclein forms oligomeric complexes with SDS micelles with relatively low α-helical structure. These micellar oligomers can efficiently nucleate aggregation of monomeric α-Synuclein, with successive formation of oligomers, protofibrils, curly fibrils and mature amyloid fibrils. N-acetylation reduces considerably the rate of aggregation of WT α-Synuclein. However, in presence of any of the early-onset Parkinson's disease mutations the protective effect of N-acetylation against micelle-induced aggregation becomes impaired. At higher SDS/protein ratios, N-acetylation favors another conformational transition, in which a second type of α-helix-rich, non-aggregating oligomers become stabilized. Once again, the Parkinson's disease mutations disconnect the influence of N-acetylation in promoting this transition. These results suggest a cooperative link between the N-terminus and the region of the mutations that may be important for α-Synuclein function.
Highly Porous Thick Thermal Barrier Coatings Produced by Air Plasma Spraying of a Plastic-Ceramic Mixed Powder (1997)

Abstract In order to increase the efficiency of heavy duty gas turbines for power generation and to reduce their emissions, higher combustion chamber temperature is required; a considerable improvement of the insulation properties of the thermal barrier coatings is therefore required. 1.5 mm thick thermal barrier coatings have been deposited by air plasma spraying a mixed polyester-zirconia powder; by this process high porosity, up to 22%, has been achieved together with a good deposition efficiency (about 50%); the coating microstructure has been thoroughly examined by quantitative image analysis, determining the pores size distribution and the vertical segmentation cracks density. Thermal shock tests showed a life improvement with respect to the state-of-art by a factor &gt; 100; relationships among thermal shock life, deposition rate, segmentation cracks density and porosity were determined. Thermal expansion and thermal diffusivity were measured up to 1200 °C; failure strength, failure strain and Young's modulus were determined by a four-point bending technique.
Rabphilin-3A: A Multifunctional Regulator of Synaptic Vesicle Traffic (1998)

We have investigated the function of the synaptic vesicle protein Rabphilin-3A in neurotransmitter release at the squid giant synapse. Presynaptic microinjection of recombinant Rabphilin-3A reversibly inhibited the exocytotic release of neurotransmitter. Injection of fragments of Rabphilin-3A indicate that at least two distinct regions of the protein inhibit neurotransmitter release: the NH2-terminal region that binds Rab3A and is phosphorylated by protein kinases and the two C2 domains that interact with calcium, phospholipid, and beta-adducin. Each of the inhibitory fragments and the full-length protein had separate effects on presynaptic morphology, suggesting that individual domains were inhibiting a subset of the reactions in which the full-length protein participates. In addition to inhibiting exocytosis, constructs containing the NH2 terminus of Rabphilin-3A also perturbed the endocytotic pathway, as indicated by changes in the membrane areas of endosomes, coated vesicles, and the plasma membrane. These results indicate that Rabphilin-3A regulates synaptic vesicle traffic and appears to do so at distinct stages of both the exocytotic and endocytotic pathways.
Theory of the voltammetric response of electrodes of submicron dimensions. Violation of electroneutrality in the presence of excess supporting electrolyte (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTheory of the voltammetric response of electrodes of submicron dimensions. Violation of electroneutrality in the presence of excess supporting electrolyteChristopher P. Smith and Henry S. WhiteCite this: Anal. Chem. 1993, 65, 23, 3343–3353Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/ac00071a002https://doi.org/10.1021/ac00071a002research-articleACS PublicationsRequest reuse permissionsArticle Views1037Altmetric-Citations140LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Purification and properties of particulate alcohol dehydrogenase from Acetobacter aceti. (1978)

Particulate alcohol dehydrogenase of acetic acid bacteria was purified to homogeneous state from Acetobacter aceti IFO 3284. The enzyme was purified about 70-fold with an overall yield of 55% from the cell homogenate by solubilization and extraction of the enzyme with Triton X-100 and subsequent fractionations on column chromatography. The purified enzyme was revealed of its properties as flavo-cytochrome complex and was composed of four different subunits having a molecular weight of 63, 000, 44, 000, 29, 000 and 13, 500. A tightly bound cytochrome component was not alcohol dehydrogenase itself and had a function as an electron acceptor in vivo. The first subunit which reacts with ethanol was shown to be a flavoprotein of the particulate alcohol dehydrogenase complex. Catalytic properties of the enzyme were also examined and the data that the enzyme is a representative as the vinegar fermenter were ob-tained.
Ligand-induced endocytosis and nuclear localization of angiotensin II receptors expressed in CHO cells (2001)

A construct (AT1R-NF) containing a "Flag" sequence added to the N-terminus of the rat AT1 receptor was stably expressed in Chinese hamster ovary cells and quantified in the cell membrane by confocal microscopy after reaction with a fluorescein-labeled anti-Flag monoclonal antibody. Angiotensin II bound to AT1R-NF and induced endocytosis with a half-time of 2 min. After 60-90 min, fluorescence accumulated around the cell nucleus, suggesting migration of the ligand-receptor complex to the nuclear membrane. Angiotensin antagonists also induced endocytosis, suggesting that a common step in the transduction signal mechanism occurring after ligand binding may be responsible for the ligand-receptor complex internalization.