gebhart/patrepeval huggingface dataset:
Comparison of factors influencing trichloroethylene degradation by toluene-oxidizing bacteria (1996)

The degradation of trichloroethylene (TCE) by toluene-oxidizing bacteria has been extensively studied, and yet the influence of environmental conditions and physiological characteristics of individual strains has received little attention. To consider these effects, the levels of TCE degradation by strains distinguishable on the basis of toluene and nitrate metabolism were compared under aerobic or hypoxic conditions in the presence and absence of nitrate and an exogenous electron donor, lactate. Under aerobic conditions with toluene-induced cells, strains expressing toluene dioxygenases (Pseudomonas putida F1, Pseudomonas sp. strain JS150, Pseudomonas fluorescens CFS215, and Pseudomonas sp. strain W31) degraded TCE at low rates, with less than 12% of the TCE removed in 18 h. In contrast, strains expressing toluene monooxygenases (Burkholderia cepacia G4, Burkholderia pickettii PKO1, and Pseudomonas mendocina KR1) degraded 36 to 67% of the TCE over the same period. Under hypoxic conditions (1.7 mg of dissolved oxygen per liter) or when lactate was added as an electron donor, the extent of TCE degradation by toluene-induced cells was generally lower. In the presence of lactate, degradation of TCE by denitrifying strain PKO1 was enhanced by nitrate under conditions in which dissimilatory nitrate reduction was observed. The results of experiments performed with strains F1, G4, PKO1, and KR1 suggested that TCE or an oxidation product induces toluene degradation and that TCE induces its own degradation in the monooxygenase strains. The role of TCE as an inducer of toluene oxygenase activity in PKO1 was confirmed by performing a promoter probe analysis, in which we found that TCE activates transcription from the PKO1 3-monooxygenase operon promoter.
1,3-Bis(diphenylphosphino)propane-bridged complexes. X-ray crystal and molecular structure of Ir2(CO)2Cl2{(.mu.-Ph2P(CH2)3PPh2}2, its reactions with hydrogen and oxygen, and the structure of Ir2(CO)2Cl2(O2){.mu.-Ph2P(CH2)3PPh2}2 (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,3-Bis(diphenylphosphino)propane-bridged complexes. X-ray crystal and molecular structure of Ir2(CO)2Cl2{(.mu.-Ph2P(CH2)3PPh2}2, its reactions with hydrogen and oxygen, and the structure of Ir2(CO)2Cl2(O2){.mu.-Ph2P(CH2)3PPh2}2Hsien Hau Wang, Louis H. Pignolet, Philip E. Reedy Jr., Marilyn M. Olmstead, and Alan L. BalchCite this: Inorg. Chem. 1987, 26, 3, 377–383Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/ic00250a008https://doi.org/10.1021/ic00250a008research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line (2006)

Berberine induces p53 expression and leads to the decrease of the mitochondrial membrane potential, Cytochrome C release and activation of caspase-3 for the induction of apoptosis.
Avaliação da Colaboração em Projeto Fundamentado em Práticas Ágeis (2013)

Companies whose value is based on the information technology are under high pressure in order to deliver their products faster and with better quality. The current level of software performance is under the expectation and therefore, client and user have shown dissatisfaction with the product. Based on these arguments, the academy and market have been betting on the fundamentals of software development methodologies that add dynamic and quality on software development process. This paper proposes to investigate the maturity level of collaboration criteria, based on Collaboration and Agile fundamentals, by applying a maturity model to evaluating collaboration in a real agile project.
Active linewidth narrowing of diode-laser-pumped monolithic nonplanar ring oscillators (1989)

Narrow linewidth operation of solid state lasers is becoming increasingly important for uses ranging from coherent communication to the search for gravity waves.
High solids-content nanosize polymer latexes made by microemulsion polymerization (1998)

Polymer nanoparticles were prepared from monomers such as styrene (St), butyl methacrylate (BMA), butyl acrylate (BA), methyl methacrylate (MMA), and methyl acrylate (MA) using a modified microemulsion polymerization process. With this process high polymer: surfactant weight ratios (7 : 1 or greater), relatively concentrated (10–30 wt.-%) latexes and small (10–20 nm) particle diameters were attained. Nucleation mechanisms were investigated through observations of the particle size change during the polymerization.
Intracellular Production of .beta.A4 Amyloid of Alzheimer's Disease: Modulation by Phosphoramidon and Lack of Coupling to the Secretion of the Amyloid Precursor Protein (1995)

The amyloid precursor protein (APP) undergoes abnormal metabolism in Alzheimer's disease, resulting in the accumulation of beta A4 amyloid in the brain. Normal APP metabolism includes the release of a truncated form (sAPP) which has been cleaved at the alpha-secretase site within the beta A4 amyloidogenic domain. However, intact forms of beta A4 protein may also be generated by the beta- and gamma-secretases. Soluble forms of beta A4 have been detected in various cell lines and in cerebrospinal fluid. Previous studies of protein kinase C activation have suggested a reciprocal relationship between sAPP secretion and beta A4 production and release. We find that phorbol ester activation of protein kinase C in untransfected SH-SY5Y neuroblastoma cells increases the release of sAPP without affecting beta A4 secretion. We provide further evidence for intracellular beta A4 production. Treatment of SY5Y cells with the protease inhibitor phosphoramidon results in a 2-fold increase in beta A4 secretion and an increase in the amount of beta A4 recovered from cell lysates, yet it does not affect sAPP secretion. The protease inhibitors thiorphan and N-[(RS)-2-carboxy-3-phenylpropanoyl]-L-leucine had no effect on beta A4 or sAPP secretion. The lysosomotropic agents chloroquine and NH4Cl decreased beta A4 secretion, providing additional evidence for the involvement of intracellular acidic compartments in the production of beta A4. Our results therefore demonstrate a double dissociation between the secretion of sAPP and beta A4 in the SH-SY5Y cell line. The effect of phosphoramidon supports previous studies which show that metalloproteases are involved in the biogenesis of beta A4.
<i>Short Communication:</i> Activating Stimuli Enhance Immunotoxin-Mediated Killing of HIV-Infected Macrophages (2008)

Abstract Strategies for purging persistent reservoirs in human immunodeficiency virus (HIV)-infected individuals may be enhanced by including agents that specifically kill virus-expressing cells. Anti-HIV envelope immunotoxins (ITs) represent one class of candidate molecules that could fulfill this function. We have previously utilized an anti-gp120 IT in conjunction with various stimulants to kill latently infected T cells ex vivo. Here we show that primary macrophages expressing HIV Env are relatively refractory to killing by IT when used alone. However, including stimulants such as prostratin or granulocyte-macrophage colony-stimulating factor to increase HIV gene expression in infected macrophages enhanced IT-mediated killing. Therefore, "activation-elimination" strategies similar to those proposed for purging the latent HIV reservoir may prove useful in clearing chronically infected macrophages in vivo.
ONO inter-poly dielectric scaling for nonvolatile memory applications (1991)

The ONO (oxide/nitride/oxide) inter-poly dielectric thickness scaling effect on electric-field-leakage-current characteristics and charge retention characteristics in nonvolatile memories are investigated. Surface top-oxide thickness strongly affects the charge leakage and retention characteristics. Thicker than 3 nm top oxide can block hole injunction from the anode. Thick top oxide can reduce leakage current in both high and low electric field regions. Moreover, it can improve charge retention characteristics in nonvolatile memory cells. Therefore, a certain amount of top oxide is required to preserve good charge retention characteristics. SiN thickness scaling leads to an improvement in charge retention characteristics. Bottom oxide has an important role in suppressing electron leakage in a low electric field region. A degraded quality thin bottom oxide leads to charge retention capability degradation. Therefore, bottom-oxide quality and thickness control is an important subject for ONO thickness scaling.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Proposed solution for improving the reliability of HSS data by integrating a queue manager (2018)

This paper propose a solution for improving the reliability of IMS HSS data by integrating a queue manager. It will interact between the I-CSCF, S-CSCF and HSS entities so that when transferring or downloading the user's profile, the HSS entity is operating normally, notifying the user that it is registered.
Extraction of important keywords in free text of questionnaire data and visualization of relationship among sentences (2009)

Recently, companies often carry out questionnaire(s) and develop marketing strategies. There are usually two types of forms for the answer of a questionnaire. One is the form to select prepared answers and the other is free text form. The true message might be in the text form rather than the numerical part, then the analysis of free text form is needed. The amount of text in a questionnaire is, however, usually large and difficult to read whole text data for analysis. This study tries to develop a free text analysis support system which visualizes relationships among respondents based on their texts and shows their opinions using graph structure of keywords. First, this paper proposes the extraction method of important keywords in their opinions based on the modification relationships. Next, it clusters the respondents interactively on visible space using MDS. Finally, it shows their opinions using HK Graph which can visualize the relationship among words with hierarchical network structure based on the co-occurrence information for the keyword graph.
An object detector based on multiscale sliding window search using a fully pipelined binarized CNN on an FPGA (2017)

An object detection problem consists of two problems: one is classification of detected object category and the other is localization. Frame object detection is used in an embedded vision systems, such as a robot, an automobile, a security camera, and a drone. These applications require high-performance computation and low-power consumption by an inexpensive device. This paper proposes multiscale sliding window based object detector using a fully pipelined binarized deep convolutional neural network (BCNN) on an FPGA. It consists of a sliding window part, a fully pipelined BCNN classifier, and an ARM processing unit for detection. Duplicate detections were filtered by using a non-maximum suppression algorithm running on the ARM processor. We propose the fully pipelined layers for the BCNN and its architecture for FPGA realization. Since the proposed BCNN circuit uses on-chip memories on the FPGA, its throughput is higher than a GPU based one with practical recognition accuracy. We trained the VGG11 based BCNN using the KITTI vision benchmark for the car detection scenario. Then, we implemented the proposed object detector on the Xilinx Inc. Zynq UltraScale+ MPSoC zcu102 evaluation board. The GPU based object detectors were too slow for the realtime application requirement (HD frame rate), with the exception of YOLOv2. As compared with the GPU implementation of YOLOv2, the proposed FPGA detector had higher recognition accuracy and lower power consumption. Compared with the YOLOv2, the proposed FPGA one is higher with respect to recognition accuracy, and its power consumption is lower than the GPU based YOLOv2. Thus, the FPGA based object detector suitable for the embedded realtime applications.
Continuous 24-Hour Monitoring of Intraocular Pressure Patterns With a Contact Lens Sensor (2012)

OBJECTIVE To examine the safety, tolerability, and reproducibility of intraocular pressure (IOP) patterns during repeated continuous 24-hour IOP monitoring with a contact lens sensor. METHODS Forty patients suspected of having glaucoma (n = 21) or with established glaucoma (n = 19) were studied. Patients participated in two 24-hour IOP monitoring sessions (S1 and S2) at a 1-week interval (SENSIMED Triggerfish CLS; Sensimed AG). Patients pursued daily activities, and sleep behavior was not controlled. Incidence of adverse events and tolerability (visual analog scale score) were assessed. Reproducibility of signal patterns was assessed using Pearson correlations. RESULTS The mean (SD) age of the patients was 55.5 (15.7) years, and 60% were male. Main adverse events were blurred vision (82%), conjunctival hyperemia (80%), and superficial punctate keratitis (15%). The mean (SD) visual analog scale score was 27.2 (18.5) mm in S1 and 23.8 (18.7) mm in S2 (P = .22). Overall correlation between the 2 sessions was 0.59 (0.51 for no glaucoma medication and 0.63 for glaucoma medication) (P = .12). Mean (SD) positive linear slopes of the sensor signal from wake to 2 hours into sleep were detected in both sessions for the no glaucoma medication group (S1: 0.40 [0.34], P < .001; S2: 0.33 [0.30], P < .01) but not for the glaucoma medication group (S1: 0.24 [0.60], P = .06; S2: 0.40 [0.40], P < .001). CONCLUSIONS Repeated use of the contact lens sensor demonstrated good safety and tolerability. The recorded IOP patterns showed fair to good reproducibility, suggesting that data from continuous 24-hour IOP monitoring may be useful in the management of patients with glaucoma. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT01319617.
Methanolysis of seed oils in flowing supercritical carbon dioxide (1996)

Abstract The direct methanolysis of triglycerides in flowing supercritical carbon dioxide by an immobilized lipase is described. The reaction system consists of two syringe pumps for substrate addition and another two syringe pumps for delivering CO 2 at 24.1 MPa. Corn oil is pumped into the carbon dioxide stream at a rate of 4 μL/min, and methanol is pumped at 5 μL/min to yield fatty acid methyl esters (FAME) at >98% conversion. Direct methanolysis of soy flakes gives FAME at similar yields. This combined extraction/reaction is performed at 17.2 MPa and 50°C. The fatty acid profiles obtained for these seed oils matches those obtained by classical chemical synthesis.
Investigation on Risk Factors of Cerebrocardiac Vascular Thrombotic Diseases in Patients with Obstructive Sleep Apnea Hypopnea Syndrome (2004)

Objective: To observe the risk factors of thrombosis in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: From February 2001 to April 2003, 24 patients with moderate and severe OSAHS (OSAHS group)and 19 healthy adults (control group) were recruited. Their blood samples were drawn at 6:00 and 16:00 respectively for testing hemocrit, platelet aggregation (PAG), whole blood viscosity (WBV), prothrombin time (PT), activated partial thromboplastin time (APTT), plasma fibrinogen (Fng) and endothelin (Er). Results: There was a significantly higher hemocrit, WBV, Fng and ET as well as a significant shortening of PT and APTT at 6:00 than that at 16:00 in OSAHS group. However, there was no significant difference in all testing items between 6:00 and 16:00 in control group. The hemocrit, WBV, PAG, plasma Fng and ET were significantly higher, and PT and APTT were obviously shorter at 6:00 in OSAHS group than those at 6:00 in control group. A higher hemocrit, PAG, plasma Fng and E, a longer PT and APTT were observed at 16:00 in OSAHS group, con-pared with those at 16:00 in control group. Conclusion: In OSAHS patients there were striking risk factors of thrombosis, which is more remarkable in the early morning than in the afternoon.
A geometric approach to 3D object comparison (2002)

Along with the development of 3D acquisition devices and methods and the increasing number of available 3D objects, new tools are necessary to automatically analyze, search and interpret these models. In this paper, we describe a novel geometric approach to 3D object comparison and analysis. To compare two objects geometrically, we first properly position and align the objects. After solving this pose estimation problem, we generate specific distance histograms that define a measure of the geometric similarity of the inspected objects. The geometric approach is very well-suited for structures with moderate variance, e.g. bones, fruits, etc. The strength of the approach is proven through the results of several tests that we performed on different data sets.
Growth of single-crystal CoSi2 on Si(111) (1982)

Single-crystal CoSi2 films have been grown under ultrahigh vacuum conditions on Si (111) by both standard deposition and molecular beam epitaxy techniques. Films were analyzed by Rutherford backscattering spectroscopy and channeling, transmission electron microscopy, and low energy electron diffraction. The films are free of grain boundaries but are rotated 180° about the normal to the Si surface. The crystalline perfection, as measured by channeling, is the best yet reported for an epitaxial silicide system. The expected hexagonal misfit dislocation arrays, along with a coarser triangular defect structure, are confined to the plane of the interface.
Energy-Based Approach for Predicting Limit Cycle Oscillations in Voltage-Mode Digitally-Controlled dc-dc Converters (2006)

This paper investigates an energy-based approach for the prediction of limit-cycle oscillations (LCOs) in digitally controlled dc-dc converters due to quantization effects on the A/D converters and digital pulse-width modulator (DPWM). Existing static and dynamic models predict the existence of only a part of limit cycle oscillations, so that extensive time-domain simulations are usually needed in order to verify the presence of limit-cycle oscillations under different load and input voltage conditions. This paper proposes an alternative approach based on the incremental energy of converter state variables, which is suited for voltage-mode digitally controlled dc-dc converters. By predicting the variation of the incremental energy due to impulse response of the voltage loop, it is possible to establish when the incremental energy becomes small enough to avoid limit-cycle oscillations. This relation, which is expressed as a function of control and converter parameters, represents a necessary condition for the elimination of limit-cycle oscillations. Extensive time-domain simulations have shown that this relation is also close to the effective limit which ensures the absence of LCOs. Simulation and experimental results confirm the validity of the proposed method.
Segmentation-free query-by-string word spotting with Bag-of-Features HMMs (2015)

Word spotting allows to explore document images without requiring a full transcription. In the query-by-string scenario considered in this paper, it is possible to search arbitrary keywords while only limited prior information about the documents is required. We learn context-dependent character models from a training set that is small with respect to the number of models. This is possible due to the use of Bag-of-Features HMMs that are especially suited for estimating robust models from limited training material. In contrast to most query-by-string methods we consider a fully segmentation-free decoding framework that does not require any pre-segmentation on word or line level. Experiments on the well-known George Washington benchmark demonstrate the high accuracy of our method.
Trimethoprim and rifampin in combination for chemoprophylaxis of household contacts of patients with invasive infections due to Haemophilus influenzae type b (1983)

We compared the effectiveness of rifampin-trimethoprim in fixed combination (3.75:1) to rifampin alone in the eradication of Haemophilus influenzae type b carriage among contacts of patients with invasive infection caused by this organism. The study population was composed of 127 index patients and 620 contacts. Twenty-six percent of contacts were colonized. Rifampin-trimethoprim eradicated carriage in 77.6% of contacts (71.1% in contacts less than 5 years, 84.2% in contacts greater than or equal to 5 years) whereas rifampin eradicated carriage in 69.9% of contacts (56.4% in contacts less than 5 years, 81.8% in contacts greater than or equal to 5 years). A single isolate resistant to rifampin and rifampin-trimethoprim was encountered. The eradication rate achieved with this regimen of rifampin-trimethoprim was too low to recommend its routine use. However, a higher dose or longer course might merit clinical trial.
Concentrations of hemoglobin fractions calculation using modified Lambert-Beer law and solving of an ill-posed system of equations (2010)

Based on the optical methods, it could be able to identify the concentrations of the hemoglobin fractions in a few seconds. An array of Light Emitting Diodes "LEDs" with different wavelengths and a photo detector were used to detect the transmitted or reflected light intensities. A system of equations was built according to the modified Lambert-Beer Law to be solved as an inverse problem. Typically practical inverse problems are all ill-posed. Even well-posed problems may be unstable or ill-conditioned when they digitalized. Also, applications in tissue spectroscopy and optical imaging result in an ill-posed problems. The difficulties involved in solving ill-posed systems are known, where large changes in the solution result from small perturbations in the right hand members of the system that can be caused by measurement tolerance or noise. A good numerical method to solve it may be beneficial in the applications to the optimization problems including linear programming and nonlinear programming. To account for the sensitivity to noise, a regularization method is usually applied to solve this sort of ill-posed problem, where a suitable regularized parameter is used to depress the bias in the computed solution by a better balance of approximation error and propagated data error. The Method has better computational efficiency and accuracy even for the highly ill-conditioned linear equations with a large disturbance on the given data. Comparing the results with that obtained from a direct solution of the system of equations, we prove well-posedness, stability and convergence of the method. The estimated hemoglobin fractions were highly correlated to the reference laboratory measurements.