gebhart/patrepeval huggingface dataset:
Bone marrow cell differential counts obtained by multidimensional flow cytometry. (1992)

Five-dimensional flow cytometric analysis of normal bone marrow aspirates was utilized to determine the frequency of neutrophils, eosinophils, monocytes, lymphocytes, nucleated erythrocytes, reticulocytes, platelets, and a cell population that included blasts of each of the cell lineages, megakaryocytes, plasma cells, and basophils. Each of these bone marrow cell populations had unique features with respect to forward light scatter, orthogonal light scatter, and staining with Thiazole-Orange, LDS-751, and CD45 labeled with Phycoerythrin (PE). The identity of the cell populations was verified by sorting each of the cell populations and subsequent light microscopic examination of the cells. The frequencies of the nucleated bone marrow cell subpopulations of 50 normal donors were for neutrophils, mean 72.3%; SD +/- 5.1; 95% limits, 70.9-73.8%; eosinophils, mean 1.8%; SD +/- 1.3; 95% limits, 1.4-2.1%; monocytes, mean, 2.8%; SD +/- 1.2; 95% limits, 2.5-3.1%; lymphocytes, mean 12.1%; SD +/- 3.6; 95% limits 11.1-13.2%; nucleated erythrocytes, mean 8.9%; SD +/- 3.9; 95% limits, 7.8-10.1%; and the cell population that included blasts of each of the cell lineages, megakaryocytes, plasma cells, and basophils, mean 1.6%; SD +/- 1.2; 95% limits, 1.3-1.9%. The percentage of reticulocytes in bone marrow aspirates from 50 normal donors correlated with the reticulocyte frequency in the peripheral blood of these donors. However, the mean frequency of reticulocytes was significantly greater (p < 0.0001) in bone marrow (mean 2.19%; SD +/- 0.88) than in peripheral blood (mean 1.71%; SD +/- 0.88). The technique could discriminate between immature and mature reticulocytes based on the brighter staining with both Thiazole-Orange and LDS-751 of the immature reticulocytes. This was confirmed by cell sorting of both reticulocyte populations, which revealed larger clumps of New Methylene Blue staining material in the brighter Thiazole-Orange and LDS-751 stained reticulocytes. The immature reticulocytes were present in normal bone marrow, but not in normal peripheral blood. As expected, a significantly greater frequency of nucleated cells was found in bone marrow aspirates (mean 0.85%; SD +/- 0.59) than in peripheral blood (mean 0.20%; SD +/- 0.11). The frequency of platelets was significantly lower in bone marrow (mean 1.24%; SD +/- 0.69) than in peripheral blood (mean 2.94%, SD +/- 1.14). Flow cytometric bone marrow analysis can provide clinical laboratories with a technique that generates quantitative bone marrow cell differentials and potentially can reduce the need for light microscopic examination of bone marrow smears.
New test to assess pilot's vision following refractive surgery. (2003)

The results of the test are simple to interpret and reveal visual performance that falls outside the normal range as a result of either significant degradation of retinal image quality (caused by increased aberrations and scattered light) or abnormal processing of visual information in the retina and/or the visual pathway.
Power loading for FBMC systems: An analysis with mercury-filling approach (2013)

This paper tackles the problem of efficient power loading in Filter-Bank based Multicarrier (FBMC) systems, being more and more often treated as the potential successor of the Orthogonal Frequency Division Multiplexing (OFDM) scheme. In particular the potential of application of the mercury-waterfilling principle for power allocation among data symbols in these systems has been analyzed. The efficiency of the proposed link adaptation scheme has been verified in the specified WiMAX-PUSC scenario, in which dedicated pilot pattern, adapted to the FBMC features, was used.
Si3N4-on-SOI Polarization Rotator-Splitter Based on TM0-TE1 Mode Conversion (2014)

A polarization rotator-splitter is demonstrated using a Si3N4 waveguide atop a silicon waveguide. The device exhibits polarization crosstalk < −19 dB, loss < 1.5 dB, and PDL < 1.0 dB over an 80 nm bandwidth.
Molybdatophosphoric Acid/NaNO<sub>2</sub>/Wet SiO<sub>2</sub> as an Efficient System for the Aromatization of 1,2‐Dihydroquinolines under Mild and Heterogeneous Conditions (2007)

Abstract A combination of molybdatophosphoric acid and NaNO2 in the presence of wet SiO2 was used as an effective oxidizing agent for the oxidation of 1,2‐dihydroquinolines to their corresponding quinoline derivatives in dichlomethane at room temperature with excellent yields.
Synthesis and rheological study of some maleic and fumaric acid stereoregular polyesters, 2. Polyesters derived from 1,4‐dibromobutane or 1,8‐dibromooctane (1988)

Abstract Configurationally pure, high‐molecular‐weight poly(butylene maleate)s, poly(butylene fumarate)s, poly(octamethylene maleate)s, and poly(octamethylene fumarate)s were synthesized by reaction of the corresponding potassium dicarboxylates and dibromoalkanes in 1‐methyl‐2‐pyrrolidone at 95 to 114°C. The polyfumarates show about ten times higher dynamic viscosities at 150°C than the polymaleates of the same limiting viscosity numbers, which might be attributed to the more extended conformations of the former.
Development of titania heated exhaust-gas oxygen sensor (1988)

In this system, the composition of the engine exhaust gas must be maintained in a narrow range around the stoichiometry point to achieve high conversion efficiency for the catalyst. The closed-loop feedback control system using an oxygen sensor has been developed for this purpose. Two types of oxygen sensors have been developed: the potentiometric type using zirconia (ZrO/sub 2/) ceramic electrolyte and the resistive type using titania (TiO/sub 2/) semiconductor ceramics. A new electrically heated sensor has been developed which is inexpensive and tolerates lead. This sensor is installed with a multilayered substrate, using thick-film titania and a special interface design.
Analysis of proteins cross-linked to DNA after treatment of cells with formaldehyde, chromate, and cis-diamminedichloroplatinum(II). (1989)

The proteins cross-linked to the DNA of cultured Chinese hamster ovary cells after exposure to cis-diamminedichloroplatinum(II) (cis-Pt), chromate, and formaldehyde were compared by two-dimensional (2D) gel electrophoresis, immunoblotting, and centrifugal assays that measured cross-link stability. Chromate and cis-Pt cross-linked seven of the same nonhistone proteins, such as actin, to DNA. In contrast, formaldehyde selectively formed histone-DNA cross-links. Immunoblotting experiments showed that all three chemicals cross-linked a 97-kDa nuclear protein to the DNA despite their different chemical reactivity with DNA and proteins. The chromate- and cis-Pt-induced cross-links were disrupted by thiourea, 2-mercaptoethanol, and EDTA, indicating that the metal could be chemically displaced from the cross-links. The formaldehyde-induced complexes required degradation with DNase 1 for the resolution of histones on 2D gels and were not chemically labile like the metal-induced cross-links. The agents and methodology used here could be applied to the study of additional nuclear proteins that bind or reside near the DNA.
Control of micromagnetics in Permalloy nanomagnets by means of indentation (2003)

The competition of exchange and magnetostatic interaction in nanomagnets is known to lead to the formation of configurational anisotropy. We present an effective method of controlling the configurational anisotropy and underlying micromagnetic configurations in isotropic Permalloy square prisms by edge indentation. Finite difference micromagnetic modeling of such indented square prisms gives five ground state micromagnetic configurations, the relative energies of which are determined by the structure size and depth of indentation. A micromagnetic phase diagram for the system is constructed on a size-indentation plane and is confirmed by direct magneto-optical measurements on nanofabricated Permalloy structures. The effect of indentation is to suppress curling micromagnetic configurations resulting in single domain behavior in indented structures as large as 400 nm.
A Curve-Fitting Approach to Estimate the Arterial Plasma Input Function for the Assessment of Glucose Metabolic Rate and Response to Treatment (2009)

The fitted input function calibrated for AA and iDV performed similarly to IDIF. Performance improved significantly using 1 late arterial sample. The proposed model can be used when an IDIF is not available or when serial arterial sampling is not feasible.
A novel trench concept for the fabrication of compensation devices (2004)

In this paper we propose a novel trench based concept for compensation devices. Our approach includes the conformal deposition of two epitaxial layers in the trench. We present simulation results indicating an improvement in Rdson*A by more than 50 % versus 600V CoolMOS as today's benchmark in compensation devices. Furthermore we demonstrate the successful implementation of the necessary single processes such as deep trench etch (aspect ratio 12:1) and conformal defect free epitaxy.
Buckling Behavior of Pultruded Monosymmetric Members (2005)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Observation of the fast response of a magnetic resonance signal to neuronal activity: a snail ganglia study (2006)

We observed the response of a magnetic resonance signal to neuronal activity in dissected snail ganglia to investigate faster responding components than the blood oxygenation level dependent (BOLD) component. To eliminate the BOLD component completely from the magnetic resonance signal, we used dissected snail ganglia which have non-magnetic hemocyanin, other than hemoglobin, as an oxygen carrying protein. To activate the snail ganglia in synchronization with the magnetic resonance signal measurement, we applied 30 Hz electrical stimulation with a pulse width of 2 s to the ganglia just before the 90 degrees RF pulse. The increase of neuronal activity in the snail ganglia after the electrical stimulation was confirmed with extracellular potential recording. The magnetic resonance signal intensity, measured with the volume selection pulse sequence in a 3.0 T MRI, decreased by about 2.97 +/- 1.10% when the ganglia were activated by the electrical stimulation. We think that the MRI signal decrease is partly due to the magnetic field produced by the neuronal current and partly due to the Lorentz force exerted on the neurons when they were firing.
Natural infection with an attaching and effacing Escherichia coli in the small and large intestines of a calf with diarrhoea (1989)

Attaching and effacing Escherichia coli were identified in the small and large intestine of a calf with naturally occurring diarrhoea. The organisms were associated with intestinal lesions and were identified by immunoperoxidase staining and transmission and scanning electron microscopy, but they did not produce Shiga-like toxin (verotoxin).
Content-Based Music Information Retrieval (CB-MIR) and Its Applications toward the Music Industry (2018)

A huge increase in the number of digital music tracks has created the necessity to develop an automated tool to extract the useful information from these tracks. As this information has to be extracted from the contents of the music, it is known as content-based music information retrieval (CB-MIR). In the past two decades, several research outcomes have been observed in the area of CB-MIR. There is a need to consolidate and critically analyze these research findings to evolve future research directions. In this survey article, various tasks of CB-MIR and their applications are critically reviewed. In particular, the article focuses on eight MIR-related tasks such as vocal/non-vocal segmentation, artist identification, genre classification, raga identification, query-by-humming, emotion recognition, instrument recognition, and music clip annotation. The fundamental concepts of Indian classical music are detailed to attract future research on this topic. The article elaborates on the signal-processing techniques to extract useful features for performing specific tasks mentioned above and discusses their strengths as well as weaknesses. This article also points to some general research issues in CB-MIR and probable approaches toward their solutions so as to improve the efficiency of the existing CB-MIR systems.
Phenotype of Barrett's Esophagus and Intestinal Metaplasia of the Distal Esophagus and Gastroesophageal Junction (2001)

The pathogenesis of short segment Barrett's esophagus (SSBE) and intestinal metaplasia (IM) of the gastroesophageal junction (IMGEJ) are poorly understood. Also, these conditions are difficult to distinguish from one another based solely on endoscopic and pathologic criteria. Therefore, the aim of this study was to evaluate the immunophenotypic features of SSBE and IMGEJ and to compare the results with lesions of known etiologies: long segment BE (LSBE) caused by reflux disease and Helicobacter pylori-induced IM of the gastric antrum (IMGA). Routinely processed mucosal biopsy specimens from 11 patients with LSBE, 17 with SSBE, 10 with IMGEJ, 16 with IMGA, 17 with a normal nonmetaplastic GEJ, and 7 patients with a normal gastric antrum were immunohistochemically stained with monoclonal antibodies to: Das1, an antibody shown to react specifically with colonic goblet cells; 45M1, an antibody that recognizes the M1 gastric mucin antigen; and cytokeratin (CK) 7 and 20, antibodies that have previously been reported to show specific staining patterns in BE versus IMGA. Also evaluated was nonintestinalized mucinous epithelium from LSBE, SSBE, and also the normal GEJ and gastric antrum. LSBE, SSBE, and IMGEJ showed similar prevalences of Das1 (91% versus 88% versus 100%) and 45M1 reactivity (100% versus 100% versus 100%), and a similar pattern of CK7/20 reactivity (diffuse strong CK7 staining of the surface and crypt epithelium, and strong surface and superficial crypt CK20 staining) (91% versus 94% versus 90%). In contrast, although 45M1 reactivity in IMGA (93%) was similar to that of the other three groups, IMGA showed a significantly lower prevalence of Das positivity (13%, p < 0.001), and only a 14% prevalence of the CK7/20 staining pattern that was predominant in the other three groups (p < 0.001). Das1, 45M1, and CK7/20 staining were similar in nonintestinalized "cardia-type" mucinous epithelium from LSBE, SSBE, and the GEJ, but all were distinct from the normal gastric antrum. In summary, the immunophenotypic features of SSBE and IMGEJ are similar and closely resemble those seen in classic LSBE, but are distinct from IMGA. This may indicate that IM in LSBE, SSBE and at the GEJ have similar biologic properties. Based on our data, SSBE and IMGEJ cannot be distinguished on the basis of their immunophenotype.
The presiding genius (1994)

This study focused on the personality traits of catastrophizing pain cognitions and HA in women with lifelong vaginismus. Our findings showed that indeed, women suffering from vaginismus are characterized by trait of HA interwoven with habitual pain catastrophizing cognitions. This study could help in the refinement of the current conceptualization and might shed light on the already available treatment options for women with vaginismus.
Premature senescence of endothelial cells: Methusaleh's dilemma (2006)

Senescence has been considered a programmed cellular response, parallel to apoptosis, that is turned on when a cell reaches Hayflick's limit. Once cells enter the senescence program, they cease to proliferate and undergo a series of morphological and functional changes. Studies support a central role for Rb protein in controlling this process after it receives senescent signals from the p53 and p16 pathways. Cellular senescence is considered an essential contributor to the aging process and has been shown to be an important tumor suppression mechanism. In addition, emerging evidence suggests that senescence may also be involved in the pathogenesis of stem cell dysfunction and chronic human diseases. Under these circumstances cells undergo stress-induced premature senecence, which has several specific features. Focusing on endothelial cells, we discuss recent advances in our understanding of the stresses and their pathways that prompt the premature senescence response, evaluate their correlation with the apoptotic response, and examine their links to the development of chronic diseases and the impaired function of endothelial progenitor cells, with the emphasis on vasculopathy. Emerging novel therapeutic interventions based on recent experimental findings are also reviewed.
Foveated endoscope objective design to combine high resolution with wide field of view (2010)

There is always a tradeoff between resolution and Field of View (FOV) in an imaging system. This limit can be due to the number of pixels in the detector, however a fundamental limit also exists in any optical system called the Space Bandwidth Product (SBP) which scales as the FOV area divided by the area of the diffraction limited spot. The SBP can only be increased by increasing the size of the optical system. In applications where the size of the optical system is constrained such as endoscopes, the SBC will ultimately limit the resolution or FOV. However, there is a way to provide both high resolution and a wide FOV without changing the total number of pixels in the image. The technique is called foveated imaging because is mimics this characteristic of the human eye in which the fovea has a higher resolution at the center of the FOV than the surrounding retina. A similar effect can be achieved optically by introducing a large amount of barrel distortion in the lens design. The result is an effective increase in the magnification at the center of the FOV, and reduced resolution but larger angular sampling at the edge. The stretching effect of the distortion can be compensated for computationally to provide an onscreen display that is not distorted, but merely appears blurred at the edges. Such an objective will enable for endomicroscopy while still providing "peripheral vision" to allow endoscopists to navigate and locate regions of interest.
An unique approach for Voltage Stability improvement with probabilistic Neural Network (2015)

This work proposes an exclusive approach for improving voltage stability limit using a Probabilistic Neural Network (PNN) classifier resulting remedial controls available in the scenario of various contingencies. The sensitivity of the whole system is analyzed to classify the weak buses with ENVCI valuation when it approaches zero. The input to the controller, named as Voltage Stability Enhancing Neural Network (VSENN) controller for training are line flows and bus voltages near the notch point of the P-V curve and the output of the VSENN is a control variable. For various contingencies, the control action that improves the voltage profile as well as stability index is observed and trained accordingly. The trained VSENN is finally tested for its robustness to improve load margin and ENVCI with new contingencies which are not trained before. The proposed approach is established in IEEE 39-bus test system.
A Simple Method for Stabilizing and Granulating Fungi (1999)

A simple method, 'Stabileze', is described for granulating fungi with water-absorbent starch, sucrose, corn oil and silica. The potential biological control fungi, Colletotrichum gloeosporioides and Fusarium oxysporum , were stabilized using this protocol. Bioassays were performed on C. gloeosporioides and showed retention of pathogenicity. Sucrose and oil were tested for their effects on the viability of F. oxysporum over time, and sucrose appears to be the most beneficial factor.
Implementation and Performance of Pipes in the V-System (1985)

The author compares the measured performance of pipes implemented by a pipe server process on top of the V message passing transport protocol versus the calculated performance of pipes implemented by an operating system kernel and supported by a dedicated protocol. He describes the implementation of pipes in the V system and presents measurements of their performance. He then calculates the performance of pipes when implemented in the kernel and supported by a dedicated protocol. The performance loss as a result of using the pipe server is shown to be about 8% for network pipes and about 25% for local pipes. Given these figures and given the fact that messages and not pipes are the principal means of interprocess communication in V, it is concluded that it is quite practical to implement pipes by a process using message passing, thereby avoiding the need for additional kernel and protocol complexity.
웹 애플리케이션 기반 UI 패턴 모델 개발과 효용성에 관한 연구 (2009)

최근 국내외 소프트웨어 개발 프로젝트의 특성인 잦은 요구사항의 변경, 단축된 비즈니스 라이프사이클, 비용절감의 압력등과 맞물려 생산성을 높이기 위한 개발 접근방식이 요구되었으며, 이에 소프트웨어의 재사용 및 높은 생산성을 제공할 수 있는 대표적인 방법이 디자인 패턴이다. 본 연구는 웹 애플리케이션 시스템 개발에 실제 적용 가능한 UI 디자인 패턴모델을 개발하기 위해 20개의 웹 애플리케이션 시스템을 표본으로 추출하여 1000여 개의 단위업무화면을 분석하였다. 또한 개발한 UI 패턴 모델을 실무 전문가(UI 디자이너, 개발자)들에게 이해도, 사용 적합성, 생산성 측면에서 검증하여 실무에 적용 가능한 모델임을 객관적으로 증명하였다.
A Probabilistic Framework for Multi-modal Multi-Person Tracking (2003)

In this paper, we present a probabilistic tracking framework that combines sound and vision to achieve more robust and accurate tracking of multiple objects. In a cluttered or noisy scene, our measurements have a non-Gaussian, multi-modal distribution. We apply a particle filter to track multiple people using combined audio and video observations. We have applied our algorithm to the domain of tracking people with a stereo-based visual foreground detection algorithm and audio localization using a beamforming technique. Our model also accurately reflects the number of people present. We test the efficacy of our system on a sequence of multiple people moving and speaking in an indoor environment.
The promoter of IL-18 binding protein: Activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein β (2002)

The IL-18 binding protein (IL-18BP) is a circulating inhibitor of the proinflammatory cytokine IL-18. It is constitutively expressed in mononuclear cells, and elevated expression is induced by IFN-gamma. In this study, we characterized the IL-18BP promoter. We first showed that induction is at the transcriptional level and requires de novo protein synthesis. The IL-18BP promoter resides within 1.6 kb DNA upstream of the first exon and includes at least six regulatory elements. We identified in the basal promoter a gamma-activated sequence (GAS) proximal to the transcription start site (base 1), followed by an IFN regulatory factor 1 response element (IRF-E) and two CCAATenhancer binding protein beta (CEBPbeta) sites, all of which are essential for basal promoter activity. Furthermore, GAS and IRF-E were essential for IFN-gamma-induced transcription. Indeed, sera of IRF-1-deficient mice lacked basal and IFN-gamma-induced IL-18BP. We found that after induction of IRF-1 by IFN-gamma, it formed a complex with CEBPbeta, which bound to the IRF-E and GAS-containing proximal DNA. In contrast, the IFN-gamma-induced signal transducer and activator of transcription 1 dimer did not associate with this GAS. In addition, we identified a silencer element and a distal enhancer at bases -1081 to -1272, which was also physically associated with IRF-1. The IRF-1-CEBPbeta complex described here probably plays a fundamental role in regulating additional IFN-gamma-responsive genes.