gebhart/patrepeval huggingface dataset:
Source enumeration in a correlated signal environment (1994)

The authors present a simple method for determining the number of signals impinging on a uniform linear array that is applicable even in the extreme case of fully correlated signals. This technique uses what they term modified rank sequences, which is a modification of the construction implicit in the matrix decomposition method of Di (1981). They prove that if a particular rank sequence stabilizes (the last two terms of the sequence are equal) to a value strictly less then the common row size of the defining block matrices, then this value equals the number of signals, provided that the number of signals has not exceeded a Bresler-Macovski (1986) type bound. Using the above characterization of stability, they formulate an algorithm that either determines the number of signals or indicates that the resolution capability of the algorithm has been exceeded. They also provide theorems that show that under certain conditions, a rank sequence can stabilize to a value strictly less than the number of signals. This result allows them to find simple counterexamples to all of the existing rank sequence methods.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A modified live canine parvovirus vaccine. II. Immune response. (1983)

The safety and efficacy of an attenuated canine parvovirus (A-CPV) vaccine was evaluated in both experimental and in field dogs. After parenteral vaccination, seronegative dogs developed hemagglutination-inhibition (HI) antibody titers as early as postvaccination (PV) day 2. Maximal titers occurred within 1 week. Immunity was associated with the persistence of HI antibody titers (titers greater than 80) that endured at least 2 years. Immune dogs challenged with virulent CPV did not shed virus in their feces. The A-CPV vaccine did not cause illness alone or in combination with living canine distemper (CD) and canine adenovirus type-2 (CAV-2) vaccines, nor did it interfere with the immune response to the other viruses. A high rate (greater than 98%) of immunity was engendered in seronegative pups. In contrast, maternal antibody interfered with the active immune response to the A-CPV. More than 95% of the dogs with HI titers less than 10 responded to the vaccine, but only 50% responded when titers were approximately 20. No animal with a titer greater than 80 at the time of vaccination became actively immunized. Susceptibility to virulent CPV during that period when maternal antibody no longer protects against infection, but still prevents active immunization, is the principal cause of vaccinal failure in breeding kennels where CPV is present. Reduction, but not complete elimination, of CPV disease in large breeding kennels occurred within 1-2 months of instituting an A-CPV vaccination program.
The History of Interior Decoration (1920)

Day by day as we are watching the elaborately mechanized systems of the nineteenth century disintegrate, or melt in the heat of passionate desire for change, as we feel civilization in a state of flux, with many still unmolten fragments of the old systems floating about, we art students must all of us be eagerly watching for forms expressive of the new epoch; for we are in the habit of reading the drama of world history through the things which man has made for his pleasure—his houses, furniture, pictures, temples. History to us is not a line extending backward into a distant past, but is rather a sphere into which all of the past is rolled, and we in the center of it have acquaintances in all epochs who tell us how the ball grew.
Structure and function of plant cell wall polysaccharides (1985)

Studies of the primary structures of polysaccharides of growing plant cell walls have shown that these structures are far more complex than was anticipated just a few years ago. This complexity can best be appreciated by considering xyloglucan, a hemicellulose present in the cell wall of both monocots and dicots, and rhamnogalacturonan II (RG-II) and rhamnogalacturonan I (RG-I), two structurally unrelated pectic polysaccharides. This realization led us to postulate that cell wall polysaccharides have functions beyond determining the size, shape and strength of plants. Some years ago we demonstrated that oligosaccharide fragments of a branched beta-linked glucan of fungal cell walls can elicit the production of phytoalexins (antibiotics) in plants by inducing the formation of the enzymes responsible for synthesis of the phytoalexins. It has now been ascertained and confirmed by synthesis that the elicitor activity resides in a very specific hepta-beta-D-glucoside. The heptaglucoside has been shown to elicit phytoalexins by activating the expression of specific genes, that is, by causing the synthesis of the mRNAs that encode the enzymes that synthesize phytoalexins. In other words, complex carbohydrates can be regulatory molecules. Further experiments established that oligosaccharide fragments of polysaccharides, produced by acid or base hydrolysis or by enzymolysis of primary cell walls of plants, also evoked defence responses in plants. Subsequently, we learned that defined fragments of polysaccharides, released from covalent attachment within plant cell walls, can function as regulators of various physiological processes such as morphogenesis, rate of cell growth and time of flowering and rooting, in addition to activating mechanisms for resisting potential pathogens. Examples of plant oligosaccharides with regulatory properties (called oligosaccharins) will be described.
User modeling and cooperative information retrieval in information retrieval systems (1999)

Article dans revue scientifique avec comité de lecture.
Minimum 20-year Followup (2008)

Hip resurfacing is an attractive concept because it preserves rather than removes the femoral head and neck. Most early designs had high failure rates, but one unique design had a femoral stem. Because that particular device appeared to have better implant survival, this study asses- sed the clinical outcome and long-term survivorship of a hip resurfacing prosthesis. Four hundred forty-five patients (561 hips) were retrospectively reviewed after a minimum of 20 years' followup or until death; 23 additional patients were lost to followup. Patients received a metal femoral prosthesis with a small curved stem. Three types of acetabular reconstructions were used: (1) cemented poly- urethane; (2) metal-on-metal; and (3) polyethylene secured with cement or used as the liner of a two-piece porous- coated implant. Long-term results were favorable with the metal-on-metal combination only. The mean overall Harris hip score was 92 at 2 years of followup. None of the 121 patients (133 hips) who received metal-on-metal articula- tion experienced failure. The failure rate with polyurethane was 100%, and the failure rate with cemented polyethylene was 41%. Hip resurfacing with a curved-stem femoral component had a durable clinical outcome when a metal- on-metal articulation was used. Level of Evidence: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate <i>AKAP10</i> in heart rhythm regulation (2007)

Sudden cardiac death due to abnormal heart rhythm kills 400,000-460,000 Americans each year. To identify genes that regulate heart rhythm, we are developing a screen that uses mouse embryonic stem cells (mESCs) with gene disruptions that can be differentiated into cardiac cells for phenotyping. Here, we show that the heterozygous disruption of the Akap10 (D-AKAP2) gene that disrupts the final 51 aa increases the contractile response of cultured cardiac cells to cholinergic signals. In both heterozygous and homozygous mutant mice derived from these mESCs, the same Akap10 disruption increases the cardiac response to cholinergic signals, suggesting a dominant interfering effect of the Akap10 mutant allele. The mutant mice have cardiac arrhythmias and die prematurely. We also found that a common variant of AKAP10 in humans (646V, 40% of alleles) was associated with increased basal heart rate and decreased heart rate variability (markers of low cholinergic/vagus nerve sensitivity). These markers predict an increased risk of sudden cardiac death. Although the molecular mechanism remains unknown, our findings in mutant mESCs, mice, and a common human AKAP10 SNP all suggest a role for AKAP10 in heart rhythm control. Our stem cell-based screen may provide a means of identifying other genes that control heart rhythm.
Conformal ultrasound imaging system for anatomical breast inspection (2012)

Ultrasound tomography has considerable potential as a means of breast cancer detection because it reduces the operator-dependency observed in echography. A half-ring transducer array was designed based on breast anatomy, to obtain reflectivity images of the ductolobular structures using tomographic reconstruction procedures. The 3-MHz transducer array comprises 1024 elements set in a 190-degree circular arc with a radius of 100 mm. The front-end electronics incorporate 32 independent parallel transmit/receive channels and a 32-to-1024 multiplexer unit. The transmit and receive circuitries have a variable sampling frequency of up to 80 MHz and 12-bit precision. Arbitrary waveforms are synthesized to improve the signal-to-noise ratio and to increase the spatial resolution when working with low-contrast objects. The setup was calibrated with academic objects and a needle hydrophone to develop the data correction tools and specify the properties of the system. The backscattering field was recorded using a restricted aperture, and tomographic acquisitions were performed with a pair of 0.08-mm-diameter steel wires, a low-contrast 2-D breast phantom, and a breast-shaped phantom containing inclusions. Data were processed with dedicated correction tools and a pulse compression technique. Objects were reconstructed using the elliptical back-projection algorithm.
Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides (2014)

Heparan sulfate and heparin are highly sulfated polysaccharides that consist of a repeating disaccharide unit of glucosamine and glucuronic or iduronic acid. The 2-O-sulfated iduronic acid (IdoA2S) residue is commonly found in heparan sulfate and heparin; however, 2-O-sulfated glucuronic acid (GlcA2S) is a less abundant monosaccharide (∼<5% of total saccharides). Here, we report the synthesis of three GlcA2S-containing hexasaccharides using a chemoenzymatic approach. For comparison purposes, additional IdoA2S-containing hexasaccharides were synthesized. Nuclear magnetic resonance analyses were performed to obtain full chemical shift assignments for the GlcA2S- and IdoA2S-hexasaccharides. These data show that GlcA2S is a more structurally rigid saccharide residue than IdoA2S. The antithrombin (AT) binding affinities of a GlcA2S- and an IdoA2S-hexasaccharide were determined by affinity co-electrophoresis. In contrast to IdoA2S-hexasaccharides, the GlcA2S-hexasaccharide does not bind to AT, confirming that the presence of IdoA2S is critically important for the anticoagulant activity. The availability of pure synthetic GlcA2S-containing oligosaccharides will allow the investigation of the structure and activity relationships of individual sites in heparin or heparan sulfate.
Improvement of the longitudinal vibration system for the hybrid transducer ultrasonic motor (2000)

This paper presents a symmetric hybrid transducer ultrasonic motor designed to produce large longitudinal vibration stress in the rotor/stator contact interface for high-torque operation. The nodal plane of the longitudinal vibration mode was adjusted to match the rotor/stator contact interface, and the piezoelectric ceramic disks for the longitudinal vibration were installed at the nodal plane of the longitudinal vibration mode for effective excitation. An experimental motor, 20 mm in diameter, using the first torsional vibration mode and the second longitudinal vibration mode was manufactured. A maximum torque of 0.8 N.m was achieved in the prototype, an improvement over previous versions.
Accuracy of Location Identification with Antenna Polarization on RSSI (2009)

Abstract—Pervasive computing applications, which are location-aware systems becoming increasingly important as part of our daily life. Real-time position localization of moving objects in an indoor environment is an encouraging technology for realizing the vision of creating numerous novel location-aware services and applications in various market segments. An off the shelf development platform that uses Radio Signal Strength Indication (RSSI) based location technique is always used for testing. In this paper we investigated at the affects of polarization on an indoor location tracking system. The target of this paper is to present an optimal design for RSSI location technology. We created a model for determining range form RSSI demonstrated that this model fits our experimental setup. Antenna polarization will affect RSSI and thus range accuracy. The experiments and its errors are carefully analyzed and found that the traditional least squares method of determining the parameters of the range model will give unacceptably high location error. A simple and cheap method of determining polarization angle is introduced with an accelerometer, which also increase the battery life of the node.
Modified oligonucleotides as alternatives to the synthesis of mixed probes for the screening of cDNA libraries. (1985)

Two simple alternatives to the synthesis of mixed oligodeoxyribonucleotide probes are described: mixed deblocking of triazolodeoxynucleosides for the A/G and C/T degeneracies or incorporation of 2-amino-2'-deoxyadenosines into a determined sequence for a higher stability of the hybridization duplexes. The synthetic oligodeoxyribonucleotides obtained were successfully tested in comparison with a classical mixed probe for their capacity to identify specific cDNA clones of human antithrombin III. The results are discussed with respect to the utilization of these synthetic oligonucleotides as hybridization probes for the isolation of cloned cDNA sequences.
Nickel, Copper and Some of their Alloys as Catalysts for Ethylene Hydrogenation<sup>1</sup> (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNickel, Copper and Some of their Alloys as Catalysts for Ethylene Hydrogenation1Richard J. Best and W. Walker RussellCite this: J. Am. Chem. Soc. 1954, 76, 3, 838–842Publication Date (Print):February 1, 1954Publication History Published online1 May 2002Published inissue 1 February 1954https://pubs.acs.org/doi/10.1021/ja01632a060https://doi.org/10.1021/ja01632a060research-articleACS PublicationsRequest reuse permissionsArticle Views791Altmetric-Citations89LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Selective Blockchain Transaction Pruning and State Derivability (2018)

Distributed ledger technologies, such as blockchain systems, have in recent years emerged as promising platforms for machine-to-machine commerce and other forms of multi-stakeholder applications. However, despite the potential demonstrated by projects such as Bitcoin, Ethereum, and Hyperledger Fabric, the disk space typically required to host a copy of a ledger may be prohibitively large for many categories of devices. In this paper, we introduce an approach for reducing ledger size in blockchain systems, based on arbitrary pruning predicate functions, allowing each network participant to independently select and remove any already applied transactions. We also show that if only pruning certain ledger transactions, the ability to derive an unmodified state data structure from the remaining transactions is maintained. The approach is validated through a supply chain use case utilizing a modified version of Hyperledger Fabric, in which ledger size is reduced by about 84.49% via selective transaction pruning.
Correlation of the Vasoconstriction Assay and Clinical Activity in Psoriasis (1985)

A large group of glucocorticosteroid formulations were assayed by the vasoconstriction test in normal skin sites and paired comparison studies in patients with psoriasis. Excellent correlation between the vasoconstriction assay and selected paired comparison studies occurred in 20 of 23 instances. In three instances, involving two glucocorticosteroid formulations tested, correlation was absent. The vasoconstrictor assay is an inexpensive and reliable method for screening glucocorticosteroid formulations for clinical activity in psoriasis.
TLR9<sup>−/−</sup> and TLR9<sup>+/+</sup> mice display similar immune responses to a DNA vaccine (2004)

Plasmid DNA continues to attract interest as a potential vaccine-delivery vehicle. However, the mechanisms whereby immune responses are elicited by plasmids are not fully understood. Although there have been suggestions regarding the importance of CpG motifs in plasmid immunogenicity, the molecular mechanisms by which CpG motifs enhance immune responses to DNA vaccines are not well understood. As Toll-like receptor 9-deficient (TLR9-/-) mice fail to respond to the adjuvant effects of CpG oligonucleotides, we used these mice to determine the effect of CpG motifs in plasmids used for DNA immunization. In the study described below, we report that DNA immunization was as effective in eliciting antigen-specific antibody and at stimulating antigen-specific interferon-gamma (IFN-gamma)-secreting cells in TLR9-/- mice as in TLR9+/+ mice. This study illustrates that DNA vaccines elicit immune responses by multiple mechanisms and demonstrates that TLR9 is not essential for the induction of immune responses following DNA immunization.
Characterization of carotenoids in soil bacteria and investigation of their photodegradation by UVA radiation <i>via</i> resonance Raman spectroscopy (2015)

A soil habitat consists of an enormous number of pigmented bacteria with the pigments mainly composed of diverse carotenoids. Most of the pigmented bacteria in the top layer of the soil are photoprotected from exposure to huge amounts of UVA radiation on a daily basis by these carotenoids. The photostability of these carotenoids depends heavily on the presence of specific features like a carbonyl group or an ionone ring system on its overall structure. Resonance Raman spectroscopy is one of the most sensitive and powerful techniques to detect and characterize these carotenoids and also monitor processes associated with them in their native system at a single cell resolution. However, most of the resonance Raman profiles of carotenoids have very minute differences, thereby making it extremely difficult to confirm if these differences are attributed to the presence of different carotenoids or if it is a consequence of their interaction with other cellular components. In this study, we devised a method to overcome this problem by monitoring also the photodegradation of the carotenoids in question by UVA radiation wherein a differential photodegradation response will confirm the presence of different carotenoids irrespective of the proximities in their resonance Raman profiles. Using this method, the detection and characterization of carotenoids in pure cultures of five species of pigmented coccoid soil bacteria is achieved. We also shed light on the influence of the structure of the carotenoid on its photodegradation which can be exploited for use in the characterization of carotenoids via resonance Raman spectroscopy.
Contact hole etch scaling toward 0.1 μm (2003)

Non-linear relation between contact etching depth and contact diameter has long been studied concerning with etching mechanism. Recently, McNevin et al. reported a linear relation between etched depth (D) and 1//spl phi/ (/spl phi/=contact diameter) for deep sub-micron contact hole etching. However, their proposed relation is not enough to access some mechanism of high-aspect ratio contact etching. Almost 10 years ago, we proposed a very simple relation for etching depth dependence on pattern width in a silicon trench etching. In the relation, 1/D linearly depended upon l/w (w=pattern width) with strong correlation. In this paper, we will propose a new simple relation between D and /spl phi/ with a small modification of our proposed relation for silicon trench, which can be expanded into deep quarter micron contact hole etching down to 0.1 /spl mu/m.
Spin clustering of accreting X-ray neutron stars as possible evidence of quark matter (2002)

A neutron star in binary orbit with a low-mass non-degenerate companion becomes a source of x-rays with millisecond variability when mass accretion spins it up. Centrifugally driven changes in density profile may initiate a phase transition in a growing region of the core parallel to what may take place in an isolated millisecond pulsar, but in reverse. Such a star will spend a longer time in the spin frequency range over which the transition occurs than elsewhere because the change of phase, paced by the spinup rate, is accompanied by a growth in the moment of inertia. The population of accreters will exhibit a clustering in the critical frequency range. A phase change triggered by changing spin and the accompanying adjustment of moment of inertia has its analogue in rotating nuclei.
An active learning framework for content-based information retrieval (2002)

We propose a general active learning framework for content-based information retrieval. We use this framework to guide hidden annotations in order to improve the retrieval performance. For each object in the database, we maintain a list of probabilities, each indicating the probability of this object having one of the attributes. During training, the learning algorithm samples objects in the database and presents them to the annotator to assign attributes. For each sampled object, each probability is set to be one or zero depending on whether or not the corresponding attribute is assigned by the annotator. For objects that have not been annotated, the learning algorithm estimates their probabilities with biased kernel regression. Knowledge gain is then defined to determine, among the objects that have not been annotated, which one the system is the most uncertain. The system then presents it as the next sample to the annotator to which it is assigned attributes. During retrieval, the list of probabilities works as a feature vector for us to calculate the semantic distance between two objects, or between the user query and an object in the database. The overall distance between two objects is determined by a weighted sum of the semantic distance and the low-level feature distance. The algorithm is tested on both synthetic databases and real databases of 3D models. In both cases, the retrieval performance of the system improves rapidly with the number of annotated samples. Furthermore, we show that active learning outperforms learning based on random sampling.