gebhart/patrepeval huggingface dataset:
Operation scheduling for FPGA-based reconfigurable computers (2009)

Many high-performance applications involve large data sets that are impossible to fit entirely within on-chip memories of even the largest FPGAs. As a result, they must be stored in off-chip SDRAMs and loaded onto the FPGAs as computations progress. Because of the high latency and energy consumption associated with off-chip memory accesses, it is important to develop efficient operation schedules that not only minimize latency of computations, but also the amount of data I/Os. We formulate this problem as a modified resource-constrained job scheduling problem. The problem is then solved using a list scheduling algorithm that takes advantage of the fast burst-mode access of SDRAMs. Results have shown that for large problem sizes, the performance of our algorithm is within 1% of a hand-optimized matrix-matrix multiplication implementation, with no memory overhead, and is within 0.03% of the theoretical minimum latency of an 8-by-8 cofactor matrix computation.
IMPROVED LASER-BASED NAVIGATION FOR MOBILE ROBOTS (2009)

An autonomous mobile system can operate as a service robot in various environments. In many man-made environments like buildings, there exist a lot of glass panes, such as windows, doors and glass walls. This can make robotics tasks more complicated, since one of the most popular sensor systems, namely laser range finder, faces problems with measuring correct distances when hitting glass surfaces. In this paper the behavior of a laser scanner with respect to glass surface is modeled using a probabilistic approach. This sensor model is employed to improve mapping and localization of a mobile robot in an office environment. Both of the applications have been tested with a real robot
Multivalent Mechanism of Membrane Insertion by the FYVE Domain (2004)

Targeting of a wide variety of proteins to membranes involves specific recognition of phospholipid head groups and insertion into lipid bilayers. For example, proteins that contain FYVE domains are recruited to endosomes through interaction with phosphatidylinositol 3-phosphate (PtdIns(3)P). However, the structural mechanism of membrane docking and insertion by this domain remains unclear. Here, the depth and angle of micelle insertion and the lipid binding properties of the FYVE domain of early endosome antigen 1 are estimated by NMR spectroscopy. Spin label probes incorporated into micelles identify a hydrophobic protuberance that inserts into the micelle core and is surrounded by interfacially active polar residues. A novel proxyl PtdIns(3)P derivative is developed to map the position of the phosphoinositide acyl chains, which are found to align with the membrane insertion element. Dual engagement of the FYVE domain with PtdIns(3)P and dodecylphosphocholine micelles yields a 6-fold enhancement of affinity. The additional interaction of phosphatidylserine with a conserved basic site of the protein further amplifies the micelle binding affinity and dramatically alters the angle of insertion. Thus, the FYVE domain is targeted to endosomes through the synergistic action of stereospecific PtdIns(3)P head group ligation, hydrophobic insertion and electrostatic interactions with acidic phospholipids.
Individual Prefabricated Titanium Implants in Reconstructive Craniofacial Surgery: Clinical and Technical Aspects of the First 22 Cases (1998)

The reconstruction of craniofacial bone defects by intraoperative modeling of implants restricts the choice of material and its biocompatibility and also reduces the predictability of the aesthetic result. These shortcomings go hand in hand with a prolonged surgical procedure time and increased stress on the patient. In contrast, modern industrial computer-aided design and computer-aided manufacturing systems allow the prefabrication of titanium implants, i.e., individual computer-based three-dimensional models of the bone defect are generated after acquisition, transfer, and evaluation of helical computed tomographic data. Based on these data, the individual shape of the implant is designed using freeform-surfaces geometries and is fabricated by a numerically controlled milling machine in a direct fashion. The conical margins of this implant are designed with a precision of 0.25 mm to the borders of the defect, and the surface contours are generated harmonically to the nonaffected neighboring contours with a constant thickness of 1.5 mm. Individual constructions for fixation with the dimensions of microplates are integrated in this process if screw holes cannot be drilled in thin overlapping implant margins. The reconstruction of 22 posttraumatic, postoperative, or primary cranial and craniofacial defects measuring up to 18 cm was performed using this new method. Wound healing was uneventful in all but one case, although some of the patients had been operated on several times before. The result was always predictable and constant using this highly precise technique, and duration of surgery was reduced dramatically.
The Distinct Roles of the N-terminal Copper-binding Sites in Regulation of Catalytic Activity of the Wilson's Disease Protein (2003)

Wilson's disease protein (WNDP) is a copper-transporting ATPase essential for normal distribution of copper in human cells. Recent studies demonstrate that copper regulates WNDP through several mechanisms. Six metal-binding sites (MBS) at the N terminus of WNDP are predicted to be involved in copper-dependent regulation of WNDP; however, specific roles of MBS remain poorly understood. To address this issue, we generated WNDP variants with mutations or truncation in the N-terminal region and characterized their functional properties. We show that copper cooperatively stimulates catalytic activity of WNDP and that this effect requires the presence of both MBS5 and MBS6. Mutations of MBS6 or MBS1-5 result in non-cooperative activation of the enzyme by copper, whereas the deletion of MBS1-4 does not abolish cooperativity. Our data further suggest that MBS5 and MBS6 together regulate the affinity of the intramembrane-binding site(s) for copper. Analysis of the copper-dependent stimulation of catalytic phosphorylation demonstrate that the MBS6 and MBS1-5 mutants have a 7-8-fold lower EC50 for copper activation, suggesting that their affinity for copper is increased. This conclusion is confirmed by a markedly decreased inhibition of these mutants by a copper chelator bathocuproine disulphonate. In contrast, deletion of MBS1-4 does not affect the affinity of sites important for catalytic phosphorylation. Rather, the MBS1-4 region appears to control access of copper to the functionally important metal-binding sites. The implications of these findings for intracellular regulation of WNDP are discussed.
Moving Object Detection and Tracking (2017)

The detection of moving objects in videos is very important in many video processing applications and background modeling is often an indispensable process to achieve this goal. Most of the traditional background modeling methods utilize color or texture information. However, color information is sensitive to illumination variations and texture information cannot be utilized to separate smooth foreground from smooth background in most cases. A new integration framework of texture and color information for background modeling, in which the foreground decision equation includes three parts (one part for color information, one part for texture information and the left part for the integration of color and texture information). This framework is able to combine the advantages of texture and color features while inhibiting their disadvantages as well. A block based method to accelerate the background modeling. Specifically, in the texture information modeling process, a single histogram model is established for each block whose bins indicate the occurrence probabilities of different patterns, which is different from the traditional multi-histogram model for block-based background modeling, and then dominant background patterns are selected to calculate the background likelihood of new coming blocks. Dynamic background and multimodal problems can be handled through this technique.
Phase Congruency based edge saliency detection and rate control for perceptual image and video coding (2016)

Phase Congruency (PC) features are firstly introduced into image and video coding field in this paper. As an effective tool to measure the edge information for image textures, PC change can be used to evaluate the compression loss, i.e. the coding distortions in image and video coding. Firstly, the compression influences on PC maps are given and analyzed. Secondly, the relationship between the consumed bits and the PC distortion are modeled. Lastly, the Mean-Squared-Error (MSE) based and PC distortion based optimized Coding Tree Unit (CTU) level bit allocation solutions are combined as a two step bit allocation and rate control method for intra frames for High Efficiency Video Coding (HEVC). Experimental results demonstrate that, compared with the state-of-the-art JCTVC-K0103 and JCTVC-M0257 methods, for small size videos, the proposed method can achieve significant R-D performance gains, and also works well on PC map preservation, quality smoothness and bit rate accuracy.
Scan impedance of RSW microstrip antennas in a finite array (2005)

Scan impedances of finite reduced surface wave (RSW) arrays are studied. Center element scan impedances of linear arrays and two-dimensional (2-D) square lattice arrays are calculated and compared with those of conventional microstrip arrays. Results show that compared with conventional microstrip arrays, broadside scan impedance of RSW arrays has less variation and converges much faster when the array size increases. Scan performance of the linear and 2-D square lattice RSW arrays are also studied. Results show that the RSW array can avoid the scan blindness (when the array spacing is greater than 0.5/spl lambda//sub 0/) and the scan impedance has much less variation than that of conventional microstrip array with the same array spacing. However, due to the size limitation of RSW elements, the grating lobes cannot be avoided. Hence, the scan region is limited to about 20/spl deg/ (with 0.75/spl lambda//sub 0/ array spacing). Compared with conventional microstrip arrays with 0.5/spl lambda//sub 0/ array spacing, the results show no favor to RSW arrays.
Low-loss optical connector between dissimilar single-mode fibers using local core expansion technique by thermal diffusion (1992)

The insertion loss in optical connectors for coupling small-core fibers or dissimilar fibers can be reduced by using thermally diffused expanded core fibers. The mode-field diameters of small-core fibers were locally expanded from 3.8 to 11.1 mu m by applying heat directly to the fibers. The average insertion loss between small-core fibers with expanded cores was 0.42 dB, which is less than half the value of 0.92 dB without thermal treatment. The improvement in the average loss between small-core and standard single-mode fibers was even greater. A value of 0.49 dB was achieved, which is less than one fifth that of 2.56 dB without treatment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Structural studies of poly(ethylenimine). 1. Structures of two hydrates of poly(ethylenimine): sesquihydrate and dihydrate (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural studies of poly(ethylenimine). 1. Structures of two hydrates of poly(ethylenimine): sesquihydrate and dihydrateYozo Chatani, Hiroyuki Tadokoro, Takeo Saegusa, and Hiroharu IkedaCite this: Macromolecules 1981, 14, 2, 315–321Publication Date (Print):March 1, 1981Publication History Published online1 May 2002Published inissue 1 March 1981https://pubs.acs.org/doi/10.1021/ma50003a017https://doi.org/10.1021/ma50003a017research-articleACS PublicationsRequest reuse permissionsArticle Views311Altmetric-Citations80LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Otitis media (1989)

Otitis media is extremely common in infants and young children and has important ramifications for the children, their families, and society in general. The essential elements of management are early diagnosis, adequate therapy with appropriate antibacterial agents, and conscientious follow-up to promptly detect and treat potential and actual complications. The primary care physician who treats young children is the critical health-care provider in the diagnosis of otitis media, initial treatment, and timely referral when appropriate.
Photopheresis and the role of the nurse. (1995)

Extracorporeal photochemotherapy (ECP, photopheresis) is a form of pheresis therapy approved by the federal Food and Drug Administration for treating the systemic manifestations of cutaneous T-cell lymphoma. Increasing evidence suggests that it may also be useful in treating many immune-related diseases, as well as in preventing and treating organ transplant rejection. Because the precise mechanism of action for photopheresis has not been clearly defined, research to determine future applications for this treatment is needed. It is important for dermatology nurses to understand photopheresis, to whom it is given, the nursing care for patients receiving photopheresis, and the current research and potential applications of this therapy.
Genética das doenças hematológicas: as hemoglobinopatias hereditárias (2008)

OBJETIVO: Sumarizar os dados disponíveis na literatura recente sobre os aspectos fisiopatológicos, de diagnóstico e tratamento das doenças falciformes e da talassemia β, hemoglobinopatias hereditárias de maior relevância nas populações. FONTES DOS DADOS: MEDLINE e SciELO, utilizando os termos hemoglobinopatias hereditárias, doenças falciformes e talassemia beta, no período de 2003 a maio de 2008. Dois livros e dois capítulos de livro foram também incluídos. SÍNTESE DOS DADOS: Foram encontrados mais de 2.000 artigos, sendo selecionados aqueles de maior pertinência e amplitude. CONCLUSÕES: As taxas de morbidade e a mortalidade das doenças falciformes e da talassemia β são ainda bastante expressivas e constituem importante desafio. Um maior conhecimento dos mecanismos fisiopatológicos tem permitido avanços significativos nas formas de tratamento e prevenção dessas doenças.
Investigating weaning using dental microwear analysis: A review (2016)

This paper provides a theoretical review and a framework of methods for using dental microwear analysis on deciduous teeth to investigate weaning processes from archaeological remains, and provides an approach to assess changes in food consumption during weaning. We review the process of weaning, which can be informative of subsistence transitions, maternal labour, demographic factors including birth spacing and infant health, and highlight the relationships between weaning, immune status, and exposure to pathogens. Prior microwear research has largely focused on adults necessitating consideration of the methods concerning deciduous teeth. Microwear can be used to discern between the consistency and fracture properties of food as enamel is removed during mastication, and is influenced by how food is prepared (for example premasticated, raw, cooked). As such, microwear provides a direct way to explore the introduction of complementary foods during weaning. A conceptual model of the potential confounders of assessing microwear in deciduous teeth including tooth biology, bite force, and the development of oral mechanics is presented. These are pertinent to understanding infant feeding, which changes in tandem with physical development and the sequence of dental eruption. This is relevant to future research for the interpretation of the microwear signatures of infants compared with adults. Understanding weaning practices and early life diet is crucial to expand and develop what we know about cultural systems, population health, nutrition, and subsistence practices in the past.
A low-power MPEG-2 codec LSI for consumer cameras (1999)

We have developed a low-power MPEG-2 video codec LSI which has MPEG-2 encoding and decoding functions, high resolution still picture functions and a progressive frame encoding function. This LSI is specifically designed for realizing compact and low cost consumer cameras.
B protein of bacteriophage mu is an ATPase that preferentially stimulates intermolecular DNA strand transfer. (1987)

A DNA strand-transfer reaction is an early step in the transposition of phage Mu. It has been shown that an efficient reaction in vitro requires, in addition to buffer and salt, only the Mu A protein, Mu B protein, host protein HU, ATP, and Mg2+. We have determined that, of the three protein factors involved, only the Mu B protein has an ATPase activity. The Mu B ATPase is stimulated by Mu A protein and DNA but not by either of these factors alone. Double-stranded DNA is a much better cofactor than single-stranded DNA, but there is no apparent sequence specificity. In the absence of the Mu B protein and/or ATP, the intermolecular Mu DNA strand-transfer reaction is extremely inefficient, and the strand-transfer products are predominantly the result of an intramolecular reaction. This contrasts with the efficient intermolecular reaction that occurs if Mu B protein and ATP are provided. The Mu B protein, in the presence of Mu A protein and protein HU, therefore, seems to facilitate interactions between potential DNA target sites and pairs of Mu DNA ends.
The Positional Magnetic Resonance Imaging Changes in the Lumbar Spine Following Insertion of a Novel Interspinous Process Distraction Device (2005)

This study shows that the X STOP device increases the cross-sectional area of the dural sac and exit foramens without causing changes in posture.
Abstract 12964: Over Expression of miR1 Leads to EAD Development in Cardiomyocytes by Increasing CaMKII and Calcium Current (2011)

Introduction: miR1 has been shown to induce cardiac arrhythmias in animal models but the mechanism is unclear. We overexpress miR1in rat cardiomyocytes and investigated the cellular mechanism of arrhythmia development. Methods: Rat cultured ventricular cardiomyocytes were infected with adenovirus-miR1 and adenovirus-GFP (control). Voltage and current clamp were used to record calcium current and action potentials at 35°C. Cells were loaded with Fura2-AM for measurement of calcium transients. Results: Action potential duration at 90% repolarization (APD 90 ) was 542.4% longer in ad-miR1 cardiomyocytes compared to control (377.1±137.2 ms vs. 58.7±7.2 ms vs., n=7, p 90 was due, in part, to a 174% increase in the incidence of early afterdepolarizations (EADs) in ad-miR1 cardiomyocytes (22±2 EADs/100 beats vs. 8±1 EADs/100 beats, n=25, P 2+ /calmodulin-dependent protein kinase II (CamKII) activation, we blocked CamKII with KN93 (1μ M) in ad-miR1 cardiomyocytes. Calcium current decreased from 18.7±0.7 pA/pF to 10.0±1.0 pA/pF, (n=11, p 90 (377.1±137.2 ms to 73.4±13.7 ms, n=11, p 90 decreased in ad-miR1 cells, but remained longer than in control cells (67.3±1.7 ms vs 18.8±1.6 ms, n=16 and 13, p 90 and that other currents may also involved in this prolongation in ad-miR1 infected cardiomyocytes. Conclusions: Overexpression of miR1 induced EADs in rat cardiomyocytes, in part, by increasing calcium current and CaMKII, which may be a mechanism of arrhythmias by miR1 overexpression in animal models.
Consolidating diverse user profiles based on the profile models of adaptive systems (2014)

Profile-based adaptivity is an important ingredient of interactive systems. Today, although users keep many profiles in different applications, adaptive systems still request them explicitly. While lingua franca methods on profiles are suggested, unless standardized, they are hardly deployed by different vendors. We present an approach to consolidate diverse user profiles based on a profile model that is supplied as input. The latter is instantiated in our Gandalf system, where user profiles from various sources are aggregated, merged and mapped to any given model, by also preserving private user attributes. No common models for profiles are assumed, neither any shared models across adaptive systems are prescribed. Our method uses a thesaurus service, while it proposes lightweight rules for structure matching and conflict resolution to accompany the input profile model. Gandalf is under implementation as a web service, and allows adaptive systems to hook custom pre- and post- processing logic on profiles using JavaScript.
Uniform Nanostructured Arrays of Sodium Rare‐Earth Fluorides for Highly Efficient Multicolor Upconversion Luminescence (2007)

Lichtbündel: Nanostrukturierte Anordnungen von NaMF4 (M=Seltenerdmetall) lassen sich mit einer Hydrothermalmethode herstellen. Sie bestehen aus Nanopartikeln mit gut einzustellenden Morphologien (Röhren, Scheiben oder Stäbe), Phasen (kubisch oder hexagonal) und Größen (80–900 nm). Ein NaYF4-System, das zusätzlich mit Er3+ und Yb3+ oder Tm3+ und Yb3+ dotiert ist, zeigt Mehrfarben-Hochkonversionsfluoreszenz (siehe Bild). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2007/z702519_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Assays for Β-Lactamase Activity and Inhibition (2007)

The ability, either innate or acquired, to produce beta-lactamases, enzymes capable of hydrolyzing the endocyclic peptide bond in beta-lactam antibiotics, would appear to be a primary contributor to the ever-increasing incidences of resistance to this class of antibiotics. To date, four distinct classes, A, B, C, and D, of beta-lactamases have been identified. Of these, enzymes in classes A, C, and D utilize a serine residue as a nucleophile in their catalytic mechanism while class B members are Zn2+-dependent for their function. Efforts have been and still continue to be made toward the development of potent inhibitors of these enzymes as a means to ensure the efficacy of beta-lactam antibiotics in clinical medicine. This chapter concerns procedures for the evaluation of the catalytic activity of beta-lactamases as a means to screen compounds for their inhibitory potency.