gebhart/patrepeval huggingface dataset:
Percutaneous thrombin injection for treatment of a splenic artery aneurysm (2006)

Splenic artery aneurysms are an uncommon entity and are usually asymptomatic when diagnosed.Treatment is based on size, with aneurysms greater than 2 cm usually undergoing surgical repair.We present a case in which percutaneous thrombin injection was used for treatment of a splenic artery aneurysm.
Characteristics of facial nerve-elicited cerebral vasodilatation determined using laser Doppler flowmetry (1991)

Cerebral cortical perfusion was monitored continuously with laser Doppler flowmetry and quantitative measurements of cerebral blood flow performed with the freely diffusible tracer 4-iodo[N-methyl-14C]antipyrine in the alpha-chloralose-anesthetized cat. The facial nerve was isolated from the brain stem via a posterior fossa craniotomy and electrically stimulated at frequencies of 1, 2, 5, 10, and 20 s-1. A stimulus-locked frequency-dependent increase in cerebral perfusion was seen in the parietal cortex; the mean maximum increase was 91 +/- 22% at 20 s-1. This compared with an absolute flow of 116 +/- 3 ml.100 g-1.min-1 at the same site. In addition, the response was associated with a marked increase in cerebral venous O2 content indicating that it is a primary neurogenic dilator response. This response could be blocked by hexamethonium but not by atropine and was thus mediated by an autonomic ganglion but not by the classical muscarinic postsynaptic receptor. Sectioning of the facial nerve did not alter cerebrovascular reactivity to hypercapnia. These data confirm the vasodilator effect of activation of the facial nerve and document its mediation through an intermediate parasympathetic ganglion. Consistent with previous data, the facial nerve does not appear to play a role in hypercapnic cerebral vasodilatation. Furthermore, this study highlights the usefulness of laser Doppler flowmetry in the cerebral circulation and in particular in the setting where repeated measures are required, such as in pharmacological studies.
The pathophysiologic rationale for biological therapies in inflammatory bowel disease. (2005)

Understanding the immunology of inflammatory bowel disease continues to underpin the vast majority of new therapies and identifies new targets. Novel approaches, such as exploiting the antiinflammatory role of cannabinoid receptors, may also prove productive in the future.
Bridging the gap between nanomagnetic devices and circuits (2008)

This paper looks at designing circuit elements that will be constructed with nanoscale magnets within the Quantum-dot Cellular Automata (QCA) computational paradigm. In magnetic QCA (MQCA) logical operations and dataflow are accomplished by manipulating the polarizations of nanoscale magnets. Wires and gates have already been experimentally demonstrated at room temperature. However, to realize more complex circuits - and eventually systems - more than just wires and gates in isolation are required. For example, gates must be inter-connected, signals must cross, etc. All structures must be controlled by the envisioned drive circuitry. In this paper, structures that will facilitate these circuit-level tasks are presented for the first time.
Downlink power allocation with CSI overhearing in an OFDMA macrocell/femtocell coexisting system (2012)

We consider the problem of Downlink (DL) power allocation at a Femtocell Base Station (FBS) in a macro-cell/femtocell coexisting system based on OFDMA transmission. To mitigate the interference to macrocell users, many conventional methods rely on the information of the interference channel states and macrocell user allocation provided by a control channel, causing large overhead increase. Instead, in our proposed method, each FBS is able to predict the subchannel allocation of macrocell users based on partially overheard Channel State Information (CSI) from the macrocell users to the Macrocell Base Station (MBS). Based on this estimation, the FBS performs subchannel and power allocation to femtocell users. With this procedure, the proposed method can mitigate the interference to macrocell users without largely increasing the control overhead. Simulations show the validity of the proposed method, providing sum-rate gains for both femtocells and macrocell users compared to reference schemes.
5‐3: Experimental and Physics‐Based Analysis of Leakage Currents for LTPS TFTs in AMOLED Displays (2021)

This paper presents extremely‐low leakage technologies in low‐temperature polysilicon (LTPS) TFTs. Experimental and physics‐based analysis of leakage currents, emphasizing the effects of process technologies and device design, are described. Small‐geometry TFTs, controlled by optimal LTPS process, dramatically reduce off‐state leakage current (I off ) by suppressing gate‐induced drain leakage (GIDL) and thermal generation currents, thus potentially offering lower frame rate operations by reducing IC clock power. Numerical device simulations, supplemented by physics‐based analysis, are performed to corroborate the remarkable low‐I off experimental results as well as more‐than‐twice enhanced on‐state current (I on ) in optimized LTPS devices.
SQLJ Part 1 (1999)

article Free AccessSQLJ Part 1: SQL routines using the Java programming language Share on Authors: Andrew Eisenberg Progress Software Corp., Bedford, MA Progress Software Corp., Bedford, MAView Profile , Jim Melton Oracle Corp., Sandy, UT Oracle Corp., Sandy, UTView Profile Authors Info & Claims ACM SIGMOD RecordVolume 28Issue 4Dec.1999 pp 58–63https://doi.org/10.1145/344816.344864Online:01 December 1999Publication History 10citation195DownloadsMetricsTotal Citations10Total Downloads195Last 12 Months6Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Amidomethylierung von Indolen (1976)

Abstract In 1‐, 2‐ oder 3‐Stellung substituierte Indole 1 reagieren mit N ‐(Hydroxymethyl)amiden zu substituierten 5‐(Acylaminomethyl)indolen 2 oder, wenn die 5‐Stellung besetzt ist, zu 4‐ und 6‐Acylaminomethylderivaten 7 – 16 . Die nach Abspaltung der Acylgruppen erhaltenen Indolverbindungen werden beschrieben. Die Anwendung der Methode wird mit der Synthese des 5‐Aminomethyl‐2‐methyltryptophans ( 20 ) gezeigt.
The Volvo-Turbo Experimental Gas Turbine (1962)

This paper gives a brief description of the Volvo experimental turbine, its working cycle, its basic components and their relative arrangement as well as some of the basic thinking behind the selection of the same. The paper also gives a short description of the new concept of a dual-geared power turbine, the combined reduction gear and high-speed hydrodynamic retarder, as well as some other new features incorporated.
Automatic verification of fault tolerance using model checking (2002)

Model checking is a technique that can make a verification for finite state systems absolutely automatic. We propose a method for automatic verification of fault-tolerant systems using this technique. Unlike other related work, which is tailored to specific systems, we are aimed at providing a general approach to verification of fault tolerance. The main obstacle in model checking is state explosion. To avoid the problem, we design this method so that it can use SMV, a symbolic model checking tool. Symbolic model checking can overcome the problem by expressing the state space and the transition relation by Boolean functions. Assuming that a system to be verified is specified by guarded commands, we define a modeling language suited for describing guarded command programs and propose a translation method from the modeling language to the input language of SMV. We show the results of applying the proposed method to various examples to demonstrate the usefulness.
Cortical NMDA Receptor Properties and Membrane Fluidity Are Altered in Alzheimer's Disease (1996)

NMDA receptor density as measured by the specific binding of [3H]MK 801 was significantly decreased (about 20%) in the frontal but not in the parietal cortex of postmortem brain samples of Alzheimer's disease (AD) patients (n = 21), when compared with control brains (n = 20). Membrane fluidity was not altered in the frontal cortex samples, but was slightly reduced in the parietal cortex samples of the AD patients. Since AD-specific histopathological changes (densities of senile plaques and neurofibrillary tangles) were about similar in both areas, it is concluded that the reductions of NMDA receptor densities in the frontal cortex is independent of AD-specific histopathological changes and of changes of membrane fluidity.
Using Bluetooth Low Energy to trigger an ultra-low power FSK wake-up receiver (2018)

We present a novel approach that utilizes BLE packets sent from generic BLE capable radios to synthesize an FSK-(like) addressable wake-up packet. A wake-up receiver system was developed from off-the-shelf components to detect these packets. It makes use of two differential signal paths separated by passive band-pass filters. After the rectification of each channel a differential amplifier compares the signals and the resulting wake-up signal is evaluated by an AS3933 wake-up receiver IC. Overall, the combination of these techniques contributes to a BLE compatible wake-up system which is more robust than traditional OOK wake-up systems. Thus, increasing wake-up range, while still maintaining a low energy budget. The proof-of-concept setup achieved a sensitivity of -47.8 dBm at a power consumption of 18.5 uW during passive listening. The system has a latency of 31.8 ms with a symbol rate of 1437 Baud.
Cytotoxic cells : basic mechanisms and medical applications (2000)

This volume synthesizes recent groundbreaking advances in our knowledge of the molecular mechanisms, biological roles, and medical applications of cytotoxic lymphocytes. Leading investigators examine current concepts on the recognition of antigen by T-cell receptors; the molecules mediating target recognition by natural killer cells; the intracellular signalling cascades triggered by these molecules; and the effector molecules that damage target cells. The contributors present new insights into the roles of cytotoxic lymphocytes in vivo in immune regulation, autoimmunity, antiviral resistance, and tumor surveillance. Several chapters explore potential medical applications of cytotoxic lymphocytes, including vaccines, tumor therapy, and treatment of HIV infection.
Potential Role of Pharmacogenomics in Reducing Adverse Drug Reactions (2001)

Our results suggest that drug therapy based on individuals' genetic makeups may result in a clinically important reduction in adverse outcomes. Our findings serve as a foundation for further research on how pharmacogenomics can reduce the incidence of adverse reactions and on the resulting clinical, societal, and economic implications.
Formational parameters and adaptive prototype instantiation for MPEG-4 compliant gesture synthesis (2003)

This paper introduces Gesture Engine, an animation system that synthesizes human gesturing behaviors from augmented conversation transcripts using a database of highlevel gesture definitions. An abstract scripting language to specify hand-arm gestures is introduced that incorporates knowledge from sign language research, psycholinguistics, and traditional keyframe animation. A new planning algorithm instantiates and adjusts gestures according to communicative context and temporal constraints obtained from a speech synthesizer The system animates an MPEG-4 compliant skeleton using Body Animation Parameters.
THIN LAYER CHROMATOGRAPHIC STUDY ON INCLUSION COMPLEX FORMATION BETWEEN CYCLODEXTRINS AND SOME FLAVONOIDS (2001)

The interaction between two flavonoids and six cyclodextrins (CDs) was studied by reversed phase charge transfer thin layer chromatography. The NH3 · H2O‒NH4Cl buffer containing various CDs (pH 9.7, 20°C) and polyamide plates were selected, respectively, as mobile and stationary phases. CDs, except for α-CD and CM-β-CD, can form inclusion complexes with flavonoids by this method. Furthermore, the inclusion capacity of different CDs was compared and the relative strength of interaction was calculated. The marked influence of CDs on the hydrophobility of drugs suggests that this interaction may modify the biological properties of drugs.
Stimulation of ATPase activity in barley (<i>Hordeum vulgare</i>) root plasma membrane after treatment of intact tissues and cell free extracts with triacontanol (1986)

Ca 2+ ‐ and Mg 2+ ‐dependent ATPase activity (EC 3.6.1.3) in a plasma membrane‐enriched fraction increased rapidly after in vivo application of physiologically active concentrations of triacontanol (TRIA) to the roots of barley ( Hordeum vulgare L. cv. Conquest) seedlings. Ca 2+ ‐ and Mg 2+ ‐dependent ATPase activity was 64 and 85% higher, respectively, in the roots of seedlings germinated in the presence of growth‐promoting concentrations of TRIA compared to controls. The increase in vivo was concentration dependent, with the greatest increase obtained at 2.3 n M TRIA. Maximal stimulation of ATPase activity of excised tissue treated with TRIA coincided with the temperature at which the barley was grown. At this temperature the plasma membrane is primarily in a mixed gel/liquid crystalline state. Pretreatment of barley roots with cyclohexamide did not alter ATPase stimulation by TRIA. Two to three times more [ 14 C]‐TRIA (mg membrane protein) −1 was found associated with plasma membrane‐enriched vesicles treated with TRIA than with vesicles enriched for mitochondrial membranes or for vesicles enriched for tonoplast, Golgi and rough endoplasmic reticulum. Both Ca 2+ ‐ and Mg 2+ ‐dependent ATPase activity increased by 40–60% within 30 min of the addition of 2.3 n M TRIA to cell‐free extracts of barley roots. The addition of octacosanol, the C 28 analogue of TRIA, to cell‐free extracts did not affect metal‐dependent ATPase activity. Consistent with many studies in the green‐house, simultaneous additions of equimolar amounts of TRIA and octacosanol to cell‐free extracts resulted in inhibition of ATPase stimulation by TRIA. TRIA may directly affect plasma membrane function in barley roots.
The effects of calcium phosphate particles on the growth of osteoblasts (1997)

With advances in ceramics technology, calcium phosphate bioceramics have been applied as bone substitutes for several decades. The focus of this work is to elucidate the biocompatibility of the particulates of various calcium phosphate cytotoxicities. Four different kinds of calcium phosphate powders, including beta-tricalcium phosphate (beta-TCP), hydroxyapatite (HA), beta-dicalcium pyrophosphate (beta-DCP), and sintered beta-dicalcium pyrophosphate (SDCP), were tested by osteoblast cell culture. The results were analyzed by cell count, concentration of transforming growth factor-beta 1 (TGF-beta 1), alkaline phosphatase (ALP), and prostaglandin E2 (PGE2) in culture media. The changes were most significant when osteoblasts were cultured with beta-TCP and HA bioceramics. The changes in cell population of the beta-TCP and HA were quite low in the first 3 days, then increased gradually toward the seventh day. The changes in TGF-beta 1 concentration in culture medium inversely related to the changes in cell population. The ALP titer in the culture media of the beta-TCP and HA were quite high in the first 3 days, then decreased rapidly between the third and seventh days. The concentrations of PGE2 in the culture media tested were quite high on the first day, decreased rapidly to the third day, and then gradually until the seventh day. The changes in the beta-DCP and SDCP were quite similar to those of HA and beta-TCP but much less significant. We conclude that HA and beta-TCP have an inhibitory effect on the growth of osteoblasts. The inhibitins effects of the HA and beta-TCP powders on the osteoblast cell cultures possibly are mediated by the increased synthesis of PGE2.
TRANSPORT OF NON-UNIFORM SEDIMENTS (1983)

Abstract Laboratory experiments lead to a way of modifying two existing transport rate formulae so that transport rates and size distributions of transported material can be predicted knowing the hydraulic conditions and the bed-material grain size distribution. The Ackers and White and the Paintal transport formulae are modified accordingly and used successfully on laboratory data. Difficulties in defining bed-material distributions and the possibility of overpassing in sand/gravel systems are reflected in the results obtained using data from four rivers.
Fusome asymmetry and oocyte determination in <i>Drosophila</i> (1995)

Germline cysts containing 16 interconnected cells (cystocytes) are produced at an early stage of Drosophila oogenesis by progenitor cells known as cystoblasts that undergo four synchronous rounds of incomplete division. During cyst formation, a region of specialized, spectrin-rich cytoplasm called the fusome traverses the intercellular connections (ring canals), linking individual cystocytes. Subsequently, 15 cystocytes begin to transport specific RNAs and other components into the remaining cell, the future oocyte. We used fusome-specific antibodies to characterize the early stages of cyst formation. During the first cystoblast division, a spherical mass of fusome material (the "spectrosome") was associated with only one pole of the mitotic spindle, revealing that this division is asymmetric. During the subsequent three divisions, the growing fusome always associated with the pole of each mitotic spindle that remained in the mother cell, and only extended through the newly formed ring canals after each division was completed. These observations suggest that fusomes help establish a system of directional transport between cystocytes that underlies oocyte determination.
Oxide-based RRAM: Unified microscopic principle for both unipolar and bipolar switching (2011)

A unified microscopic principle is proposed to clarify resistive switching behaviors of transition metal oxide based resistive random access memories (RRAM) for the first time. In this unified microscopic principle, both unipolar and bipolar switching characteristics of RRAM are correlated with the distribution of localized oxygen vacancies in the oxide switching layer, which is governed by the generation and recombination with dissociative oxygen ions. Based on the proposed microscopic principle, an atomistic simulation method is developed to evaluate critical memory performance, and successfully conduct the device optimization. The experimental data are well in line with the developed simulation method.
Atypical meiosis and joint segregation of biochemical loci in Agaricus brunnescens (1983)

Single spore progeny (173) from a cross of two homokaryotic lines derived from a four-spored basidium were characterized etectrophoretically. Loci segregated in ratios similar to those of four-spored mushrooms. Linkage of two peptidase loci was detected (r = 0.078). Gene to centromere distances were determined for the two peptidase loci (Pep-1, r = 0.118; Pep-2, r = 0.196) and for the independent locus encoding for aspartate aminotransferase (r = 0.084). A nonrandom segregation of centromeres at metaphase II was postulated to account for the phenotypic distributions observed. Sister centromeres apparently migrate preferentially into the same spore instead of into opposite spores as is characteristic for this species.
Towards the clinical application of laser-induced breakdown spectroscopy for rapid pathogen diagnosis: the effect of mixed cultures and sample dilution on bacterial identification (2010)

Laser-induced breakdown spectroscopy has been utilized to classify and identify bacterial specimens on the basis of their atomic composition. We have characterized the effect that the presence of a second bacterial species in the ablated specimen had on the identification of the majority species. Specimens with a reduced number of bacterial cells (approximately 2500) were identified with 100% accuracy when compared to undiluted specimens. In addition, a linear dependence of the total spectral power as a function of cell number was determined. Lastly, a high selectivity was obtained for a LIBS-based analysis of nine separate bacterial strains from four genera.
Non-Centrosymmetric Lamellar Structures in the Associating Blends of Tri- and Diblock Copolymers (2010)

We consider lamellar morphologies in the mixtures of AC diblock and ABC triblock copolymers and show that a proper functionalization of the end blocks of the triblock and diblock copolymer chains by donor and acceptor functional groups, respectively, could result in occurrence of the thermodynamically stable noncentrosymmetric lamellar structures in such mixtures. Depending on the chemical nature of the donor-acceptor bond (i.e., the values of the effective entropy Sbond and energy E per one bond), the typical phase diagrams could contain the upper and lower triple points where the pure diblock, pure triblock and noncentrosymmetric lamellae of a finite composition coexist. With increase of the association strength the triple points merge and the noncentrosymmetric lamellae become thermodynamically favorable at all temperatures. The boundary on the (Sbond ,E)-plane, which separates the regions corresponding to different types of the phase behavior, is found. The influence of the architecture of the system and the chemical nature of the donor-acceptor bond on the stability of the noncentrosymmetric lamellae is analyzed and typical phase diagrams are presented.
Blood flow distribution and tissue allometry in channel catfish (1999)

Blood flow (as percentage of cardiac output) in fasted channel catfish acclimated to 21°C was directed primarily to white muscle (72%) followed by head kidney (5·7%), red muscle (5·5%), trunk kidney (3·1%), liver (2·2%), swim bladder (1·4%) and skin (1·1%). The stomach, intestines, pyloric caeca, gonads, brain, abdominal fat and spleen contained <0·5% of blood flow. There was considerable interfish variation among blood flow distribution to visceral organs with substantial spatial heterogeneity of blood flow to white muscle. The spatial heterogeneity of flow to muscle prevented accurate estimation of total flow to this tissue based on the microsphere deposition of a few sub‐samples. Instead, a novel approach, based on the whole animal counting of the eviscerated carcass was used to measure blood flow to white muscle. The scaling relationships for tissue mass in catfish (63–1873 g) followed the allometric equation (aW b ) and tended to exhibit negative allometry, with organ weight decreasing in proportion to body weight. The b values for most tissues ranged between 0·83 and 1·0. The relative mass of the brain showed the greatest decline and with a b value of 0·32. The results, together with previous data on cardiac output, permitted calculation of organ blood flow rates in channel catfish. © 1999 The Fisheries Society of the British Isles
Threshold Temperature Sensors with Tunable Properties (2007)

Abstract Thermochromic polymer/dye blends based on small amounts (0.6–2.3 wt.‐%) of chromogenic sensor dyes and glassy amorphous polymers were prepared. Subjecting melt‐processed, quenched blends to temperatures above T g leads to permanent and pronounced changes of their absorption and fluorescence spectra as a result of phase separation and assembly of dye aggregates. The influence of dye structure and polymer T g on the aggregation kinetics of these blends was investigated. It is shown that increasing the length of the dye's rigid core leads to slower aggregation rates due to limited mobility in the polymer. The threshold of the color change can be tailored by adjusting the polymer T g , as was shown by the systematic investigation of blends based on poly(alkyl methacrylate) copolymers of varying composition. magnified image