gebhart/patrepeval huggingface dataset:
Recent advances in algorithmic learning theory of the Kanban cell neuron network (2013)

A novel algorithm of learning is defined as the Kanban cell neuron model (KCNM). The analysis captures the salient properties of the concrete application of the associated look up table (LUT). The purpose of this system is to foster a structure for machine cognition. The Kanban cell (KC) forms the basis of mapping human neurons into logical networks. The Kanban cell neuron (KCN) maps nine input signals of the dendrites into one output signal of the axon. The logical mechanism is the multivalued logic of four-valued bit code as a 2-tuple of the set {00, 01, 10, 11}. The LUT is indexed by 18-bits as input for output of 2-bits. In a preferred hardware implementation, the rate of processing is 1.8 BB KCNs per second on a $29 device.
Head and media requirements for high density recording (2003)

The extension of magnetic recording to very high areal density requires that all the critical parameters of the system be reduced to extremely small values. The recording head parameters have to be scaled down, as well as the media magnetic parameters and the media thickness. Furthermore, pulse-slimming equalization techniques are effective in increasing the recording density by reducing intersymbol interface and eliminating negative sidelobes. The author discusses the limitations of conventional ferrite heads, and the advantages of thin-film inductive heads deposited by sputtering and/or electrodeposition onto a very hard ceramic wafer the structure of the head elements being defined by photolithography and dry and wet etch steps, and thin-film magnetoresistive read heads. The latter are particularly advantageous on inner tracks of small-diameter disk drives where linear velocity is relatively slow. Integrating a magnetoresistive read head with an inductive write head not only improves the readback sensitivity but also solves track interference problems during reading, since the width of the read element can be made narrower than the width of the write head. Critical requirements for longitudinal-recording media in general and thin-film disks in particular are also considered.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Repression of adenylate cyclase in the genus Bordetella. (1982)

Virulent phase I strains of Bordetella pertussis synthesize the regulatory metabolite adenosine 3',5'-cyclic monophosphate (cAMP); whereas, non-virulent phase IV strains are unable to do so. These findings were confirmed and extended using additional strains of B. pertussis as well as strains of Bordetella parapertussis and Bordetella bronchiseptica. Levels of adenylate cyclase activity and subsequent cAMP production were found to correlate. High adenylate cyclase activity during exponential phase was followed by an accumulation of cAMP during late log and throughout stationary phase. Measurements obtained during the X- to C-mode transition process indicated that adenylate cyclase is subject to complete repression.
Antioxidant Constituents in the Fruits of <i>Luffa cylindrica </i>(L.) Roem (2006)

Hydrophilic antioxidant constituents in the fruits of the vegetable Luffa cylindrica (L.) Roem (sponge gourds) were separated by an antioxidant-guided assay to yield eight compounds: p-coumaric acid (1), 1-O-feruloyl-beta-D-glucose (2), 1-O-p-coumaroyl-beta-D-glucose (3), 1-O-caffeoyl-beta-D-glucose (4), 1-O-(4-hydroxybenzoyl)glucose (5), diosmetin-7-O-beta-D-glucuronide methyl ester (6), apigenin-7-O-beta-D-glucuronide methyl ester (7), and luteolin-7-O-beta-D-glucuronide methyl ester (8). The eight compounds were isolated by high-speed countercurrent chromatography and identified by electrospray ionization-mass spectrometry and NMR analysis, and the antioxidant activity was evaluated by the radical scavenging effect on the 1,1-diphenyl-2-picrylhydrazyl radical. High-performance liquid chromatography analysis showed that a total amount of the eight compounds in the dried gourds without skin was about 1%. The results demonstrate that the consumption of sponge gourds can supply some antioxidant constituents to human body.
EVIDENCE FOR ANTITHROMBIN III INVOLVEMENT IN THE ANTI‐COAGULANT ACTIVITY OF CELLULOSE SULPHATE (1980)

1 Cellulose sulphate, like heparin, prolonged the clotting time in partial thromboplastin time (PTT) assays, inhibited the amidolytic activity of thrombin, was without effect on amidolysis catalysed by activated coagulation factor X(Xa), and potentiated the inhibition of both thrombin and Xa by antithrombin III (AT). 2 The anticoagulant activity of cellulose sulphate in PTT assays was, like that of heparin and heparin sulphate, but unlike that of dermatan sulphate, reduced by prior incubation of plasma with antiserum specific for AT. 3 These results, which suggest that the anticoagulant activity of cellulose sulphate is at least partially mediated through AT, are discussed in terms of the structural features of polysaccharides required for AT activation.
Champagne Prototyping: A Research Technique for Early Evaluation of Complex End-User Programming Systems (2005)

Although a variety of evaluation techniques are available to researchers of visual and end-user programming systems, they are primarily suited to evaluation of research systems. It is important to have evaluation techniques suitable for real-world programming environments, in order to satisfy real-world product managers of the usefulness of proposed new features. To help fill this gap, we present a new evaluation technique, based in part on Cognitive Dimensions and Attention Investment, called "Champagne Prototyping". The technique is an early-evaluation technique that is inexpensive to do, yet features the credibility that comes from being based on the real commercial environment of interest, and from working with real users of the environment.
The ‘starting plume’ in neutral surroundings (1962)

The advancing front of a buoyant plume which is being established in uniform surroundings has some properties in common with the plume, while in other respects it behaves more like a ‘thermal’ released from rest. The solutions for these two cases cannot be matched directly, since the dependence of velocity on height is different. It is shown here that a similarity solution, which is consistent with the equations describing both parts of the flow, can be obtained once it is recognized that the velocity of the front may be less than that of the steady plume. The cap moves with a constant fraction of the plume velocity at the same level, and the total buoyancy in the cap is increasing, so a modification of the simple relations for thermals is required. This prediction is verified experimentally, and numerical values for the ratio of the velocities and the rate of increase of the cap radius with height determined. The extreme front of plume cap advances at about 0·6 times the mean velocity on the axis of a steady plume, and it spreads at just over half the angle of a thermal. This implies a smaller rate of entrainment and therefore a smaller rate of dilution per unit height compared with a thermal, especially since about half of the fluid mixed into the cap comes from the plume below. The model allows one to estimate the time necessary for convection from a known steady source on the ground to lead to the formation of a cloud.
Short-Chain Fatty Acids from <i>Cutibacterium acnes</i> Activate Both a Canonical and Epigenetic Inflammatory Response in Human Sebocytes (2019)

The regulation of cutaneous inflammatory processes is essential for the human skin to maintain homeostasis in the presence of the dense communities of resident microbes that normally populate this organ. Forming the hair follicle-associated sebaceous gland, sebocytes are specialized lipid-producing cells that can release inflammatory mediators. Cytokine and chemokine expression by pilosebaceous epithelial cells (i.e., sebocytes and follicular keratinocytes) has been proposed to contribute to the common human skin disease acne vulgaris. The underlying mechanisms that drive inflammatory gene expression in acne-involved pilosebaceous epithelial cells are still unknown because almost all sebaceous follicles contain dense concentrations of bacteria yet only some show an inflammatory reaction. In this study, we hypothesized that metabolites from the abundant skin-resident microbe <i>Propionibacterium acnes</i> can influence cytokine expression from human sebocytes. We show that short-chain fatty acids produced by <i>P. acnes</i> under environmental conditions that favor fermentation will drive inflammatory gene expression from sebocytes. These molecules are shown to influence sebocyte behavior through two distinct mechanisms: the inhibition of histone deacetylase (HDAC) activity and the activation of fatty acid receptors. Depletion of HDAC8 and HDAC9 in human sebocytes resulted in an enhanced cytokine response to TLR-2 activation that resembled the transcriptional profile of an acne lesion. These data provide a new insight into the regulation of inflammatory gene expression in the skin, further characterize the contribution of sebocytes to epidermal immunity, and demonstrate how changes in the metabolic state of the skin microbiome can promote inflammatory acne.
ANTIBACTERIAL PROPERTIES OF CHITOSAN IN WATERBORNE PATHOGEN (2002)

The antimicrobial properties of chitosan, a derivative of chitin, were investigated in the solid and liquid culture against bacteria associated with waterborne disease in order to assess the potential for using chitosan as a natural disinfectant. Six strains which included three gram-negative and three gram-positive bacteria were studied. The effects of the deacetylation degree, concentration, and molecular weight of chitosan on antibacterial activities were assessed. Chitosan exhibited the highest antibacterial activity against the Pseudomonas aeruginosa on the solid agar. Similar tendency was found when the bacteria were cultivated in liquid broth. The higher deacetylation degree and higher concentration of chitosan cause the higher antibacterial activities. The effect of molecular weight of chitosan on the inhibition efficacy of bacteria is dependent on the species of bacteria. Escherichia coli is sensitive to chitosan during its death phase and logarithmic phase. The antibacterial mechanism of chitosan was illustrated by the surface charge and persistence length. Results indicated that chitosan is potential as a natural disinfectant.
CMOS technology characterization for analog and RF design (2002)

Characterization of CMOS technologies for digital applications often proves inadequate for analog and RF design. This paper describes a set of characterization vehicles and tests that quantify the analog behavior of active and passive devices in CMOS processes, in particular, properties that are not represented accurately in SPICE models. Test structures and circuits are introduced for measuring speed, noise, linearity, loss, matching, and dc characteristics.
Treatment alternatives for impotence (1990)

More than 10 million men in the United States are chronically impotent. Fortunately, significant advances have been made in psychotherapy, pharmacologic management, arterial and venous surgery, penile prosthesis implantation, and use of external devices so that most find a satisfactory solution. After their dysfunction is sufficiently evaluated and the most appropriate treatment option is applied, most men achieve erectile capability sufficient for intercourse.
On the duality between fast QR methods and lattice methods in least squares adaptive filtering (1991)

The authors show that fast QR methods and lattice methods in least squares adaptive filtering are duals and follow from identical geometric principles. Whereas the lattice methods compute the residuals of a projection operation via the forward and backward prediction errors, the QR methods compute instead the weights used in the projections. Within this framework, the parameter identification problem is solved using fast QR methods by showing that the reflection coefficients and tap parameters of a least squares lattice filter operating in the joint process mode are immediately available as internal variables in the fast QR algorithms. This parameter set can be readily exploited in system identification, signal analysis, and linear predictive coding, for example. The relations derived also lead to a fast least squares algorithm of minimal complexity that is a hybrid between a QR and a lattice algorithm. The algorithm combines the order recursive properties of the lattice approach with the robust numerical behavior of the QR approach.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Two-Step Preparation for Catalyst-Free Biodiesel Fuel Production (2004)

Biodiesel fuel was prepared by a two-step reaction: hydrolysis and methyl esterification. Hydrolysis was carried out at a subcritical state of water to obtain fatty acids from triglycerides of rapeseed oil, while the methyl esterification of the hydrolyzed products of triglycerides was treated near the supercritical methanol condition to achieve fatty acid methyl esters. Consequently, the two-step preparation was found to convert rapeseed oil to fatty acid methyl esters in considerably shorter reaction time and milder reaction condition than the direct supercritical methanol treatment. The optimum reaction condition in this two-step preparation was 270°C and 20 min for hydrolysis and methyl esterification, respectively. Variables affecting the yields in hydrolysis and methyl esterification are discussed.
Chrysotherapy in psoriatic arthritis (1978)

Chrysotherapy was given to 14 patients with refractory psoriatic polyarthritis and to a comparable group of 42 patients with rheumatoid arthritis. The psoriatic patients had a higher rate of remission on gold and less severe toxicity than the rheumatoid arthritis patients. Psoriatic skin lesions were not affected by chrysotherapy.
Abstract 4629: Long-Term Open Label Extension of the Prevention of Embolic and Thrombotic Events on Dabigatran in Atrial Fibrillation (PETRO- Ex study) (2008)

Dabigatran is an oral direct thrombin inhibitor (DTI), which has a rapid onset of action and can be given twice daily (b-i-d) without anticoagulation monitoring. To determine the long term safety and efficacy of dabigatran in patients with atrial fibrillation (AF). AF patients (n=502) from 53 centers in Denmark, the Netherlands, Sweden and the United States were enrolled in the PETRO study, a 12 week comparison between dabigatran (50, 150, and 300 mg b-i-d) and warfarin (INR 2–3). 361 dabigatran patients were rolled over into a long term extension trial (PETRO-Ex). The warfarin patient arm (n=70) was discontinued. All patients were initially maintained on the same dabigatran doses as in PETRO except the 50 mg b-i-d dose group who were switched to 150 mg once daily (qd). At entry, patients were 70 years old (mean age), 19% female, median AF duration of 4.2 years, and had a median of 3 stroke risk factors. Maximum and mean follow-up times were 51 and 29 months respectively. Due to higher frequency of major bleeding events in 300 mg b-i-d group and thromboembolic events in 150 mg qd group, they were switched to dabigatran 300 mg qd or 150 mg b-i-d groups. PETRO and PETRO-Ex results: Events reported as absolute number of patients (per 100 patient-years) Thromboembolic event rates were lowest in the dabigatran 150 and 300 mg b-i-d groups. Major bleeding was most frequent in the 300 mg b-i-d group. No significant liver function abnormalities were noted in any of the dabigatran groups. The balance between stroke and bleeding risk supported dabigatran doses between 100 and 150 mg b-i-d for the ongoing phase 3 Randomized Evaluation of Longterm anticoagulation therapY (RELY) trial.
Skeletal Muscle for Cardiac Assist (1995)

Although current efforts at cardiomyoplasty have not produced the anticipated clear-cut benefits in cardiac function, replicable improvements in subjective function have resulted. Efforts at optimizing conditioning protocols, skeletal muscle strength, and timing of skeletal muscle assist devices should provide further improvements in cardiomyoplasty. Further work with alternative ways of configuring skeletal muscle for cardiac assist is extremely promising. SMVs, in particular, offer potential to augment cardiac function directly or indirectly powering pumps. Work in all these areas is in early stages, but the future is bright.
Performance Isolation in Cloud Storage Systems (2013)

Cloud computing enables data centres to provide resource sharing across multiple tenants.\nThis sharing, however, usually comes at a cost in the form of reduced isolation\nbetween tenants, which can lead to inconsistent and unpredictable performance. This variability\nin performance becomes an impediment for clients whose services rely on consistent,\nresponsive performance in cloud environments. The problem is exacerbated for applications\nthat rely on cloud storage systems as performance in these systems is a ffected by disk\naccess times, which often dominate overall request service times for these types of data\nservices.\nIn this thesis we introduce MicroFuge, a new distributed caching and scheduling middleware\nthat provides performance isolation for cloud storage systems. To provide performance\nisolation, MicroFuge's cache eviction policy is tenant and deadline-aware, which\nenables the provision of isolation to tenants and ensures that data for queries with more\nurgent deadlines, which are most likely to be a ffected by competing requests, are less likely\nto be evicted than data for other queries. MicroFuge also provides simplifi ed, intelligent\nscheduling in addition to request admission control whose performance model of the underlying\nstorage system will reject requests with deadlines that are unlikely to be satisfi ed.\nThe middleware approach of MicroFuge makes it unique among other systems which\nprovide performance isolation in cloud storage systems. Rather than providing performance\nisolation for some particular cloud storage system, MicroFuge can be deployed on top of\nany already deployed storage system without modifying it. Keeping in mind the wide\nspectrum of cloud storage systems available today, such an approach make MicroFuge very\nadoptable.\nIn this thesis, we show that MicroFuge can provide signifi cantly better performance\nisolation between tenants with di fferent latency requirements than Memcached, and with\nadmission control enabled, can ensure that more than certain percentage of requests meet\ntheir deadlines.
Radar detection in K-distributed clutter (1994)

The paper compares two newly proposed detection schemes for targets in K-distributed clutter: the first implements generalised likelihood ratio test, and the second represents a discrete realisation of the classical Neymann-Pearson detector. Results indicate that the two optimisation strategies yield substantially equivalent performance, but the generalised likelihood ratio test is simpler in its structure and offers some additional advantages both at the design and at the analysis stage.
Vibration (1999)

Maintaining the outstanding features and practical approach that led the bestselling first edition to become a standard textbook in engineering classrooms worldwide, Clarence de Silva's Vibration: Fundamentals and Practice, Second Edition remains a solid instructional tool for modeling, analyzing, simulating, measuring, monitoring, testing, control
Whirlpool-associated Pseudomonas aeruginosa urinary tract infections. (1983)

Three previously healthy outpatients had urinary tract infection caused by Pseudomonas aeruginosa. Investigation disclosed that all three patients had been exposed to whirlpool baths within 48 hours before the onset of symptoms. Pseudomonas aeruginosa was isolated from the whirlpool bath associated with each case. Whirlpool baths and spas are commonly contaminated with Pseudomonas and have in the past been associated with rash illness and folliculitis. In addition to these skin infections, our results indicate that whirlpool bath or spa exposure may be an emerging risk factor associated with Pseudomonas urinary tract infections among outpatients.
Energy Aware Network Operations (2009)

Networking devices today consume a non-trivial amount of energy and it has been shown that this energy consumption is largely independent of the load through the devices. With a strong need to curtail the rising operational costs of IT infrastructure, there is a tremendous opportunity for introducing energy awareness in the design and operation of enterprise and data center networks. We focus on these networks as they are under the control of a single administrative domain in which network-wide control can be consistently applied. In this paper, we describe and analyze three approaches to saving energy in single administrative domain networks, without significantly impacting the networks' ability to provide the expected levels of performance and availability. We also explore the tradeoffs between conserving energy and meeting performance and availability requirements. We conduct an extensive case study of our algorithms by simulating a real Web 2.0 workload in a real data center network topology using power characterizations that we obtain from real network hardware. Our results indicate that for our workload and data center scenario, 16% power savings (with no performance penalty and small decrease in availability) can be obtained merely by appropriately adjusting the active network elements (links). Significant additional savings (up to 75%) can be obtained by incorporating network traffic management and server workload consolidation.
Usage of a DNA Aptamer as a Ligand Targeting Microcystin (2001)

Abstract Microcystin is a bacterial hepatotoxin generated from the cyanobacteria causing waterblooms. A DNA aptamer binding to microcystin was screened by the in vitro selection method of twelve rounds in order to obtain a sorbent suitable for a microcystin detection system. The obtained DNA aptamer showed specific binding to microcystin. The direct detection range using an immobilized aptamer and a surface plasmon resonance biosensor was 50 μ/ml to 1000 μ/ml. Key Words: DNA aptamer in vitro selectionmicrocystinsurface plasmon resonance
Hearing Health Risk in a Population of Aircraft Carrier Flight Deck Personnel (2004)

This study evaluated the risk to hearing health associated with duty on the flight deck of a Nimitz class aircraft carrier. Descriptive data includes time-weighted average noise exposure and an evaluation of temporary threshold shift for a group of nonaviator flight deck personnel (FD), and a comparison of accrued permanent threshold shift among three shipboard occupational groups that had been matched for years of military service. The study participants included 76 FD personnel in a high-exposure group, 77 engineers in a moderate-exposure group, and 52 administrative personnel who were considered to have low occupational noise exposure. The study found a mean FD time weighted average of 109 dBA over workdays averaging 11.5 hours. Only 2 (4%) of 52 administrative personnel had any appreciable hearing loss (defined as worse than 20 dB at any frequency 1,000 through 4,000 Hz), whereas FD and engineers demonstrated 17% and 27% hearing impairment, respectively.
A Weight Compensation Mechanism with a Non-Circular Pulley and a Spring: Application to a Parallel Four-bar Linkage Arm (2010)

We propose a new weight compensation mechanism with a non-circular pulley and a spring. We show the basic principle and numerical design method to derive the shape of the non-circular pulley. After demonstration of the weight compensation for an inverted/ordinary pendulum system, we extend the same mechanism to a parallel four-bar linkage system, analyzing the required torques with transposed Jacobian matrices. Finally, we develop a 3 D.O.F manipulator with relatively small output actuators and verify that the weight compensation mechanism greatly contributes to decrease static torques to keep the same posture within manipulator's work space.