gebhart/patrepeval huggingface dataset:
Solar powered airship-challenge and chance (2002)

In this project the total new construction of a small ultra lightweight solar powered airship was realized within 16 months. The objective was to demonstrate the feasibility and with that to show one possible ecological alternative within some areas of air traffic. Several technical challenges had to be overcome. A high efficient lightweight photovoltaic generator with foil modules of crystalline silicon cells could be realized and examined regarding the behaviour under various mechanical load conditions. The static and dynamic load tests at the photovoltaic modules are very promising regarding the application of lightweight crystalline silicon foil modules on bent and flexible surfaces. This offers the chance to develop new application areas for photovoltaics, not least for the development of a zero emission transport system or vehicle.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Visual interfaces for solids modeling (1995)

Article Free Access Share on Visual interfaces for solids modeling Authors: Cindy Grimm Department of Computer Science, Box 1910, Brown University, Providence, RI Department of Computer Science, Box 1910, Brown University, Providence, RIView Profile , David Pugmire Department of Computer Science, University of Utah, Salt Lake City, UT Department of Computer Science, University of Utah, Salt Lake City, UTView Profile Authors Info & Claims UIST '95: Proceedings of the 8th annual ACM symposium on User interface and software technologyDecember 1995 Pages 51–60https://doi.org/10.1145/215585.215652Published:01 December 1995Publication History 7citation479DownloadsMetricsTotal Citations7Total Downloads479Last 12 Months12Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
A New Emericellopsis from Wisconsin, with Notes on Other Species (1961)

SUMMARYA new antibiotic-producing species of Emericellopsis, E. microspora Backus and Orpurt, is described. This taxon, which belongs to the small-spored section of the genus, appears to be most closely related to E. minima Stolk. The new entity occurs in considerable abundance in the soil of wet prairies in Wisconsin but has not been encountered in any other type of habitat during a 10-year survey of the mycoflora of undisturbed soils of this state.Emericellopsis terricola var. glabra van Beyma is raised to species rank as E. glabra (van Beyma) Backus and Orpurt. The substantial differences in morphology and physiology which separate this entity from E. terricola van Beyma are recorded. An Australian isolate of Emericellopsis which is a strong producer of cephalosporins has been referred to E. glabra.Observations on the effect of certain environal factors on growth and development in various species of Emericellopsis are reported.
Nucleotide sequence of the secA gene and secA(Ts) mutations preventing protein export in Escherichia coli (1988)

The DNA sequence of the secA gene, essential for protein export in Escherichia coli, was determined and found to encode a hydrophilic protein of 901 amino acid residues with a predicted molecular weight of 101,902, consistent with its previously determined size and subcellular location. Sequence analysis of 9 secA(Ts) mutations conferring general protein export and secA regulatory defects revealed that these mutations were clustered in three specific regions within the first 170 amino acid residues of the SecA protein and were the result of single amino acid changes predicted to be severely disruptive of protein structure and function. The DNA sequence immediately upstream of secA was shown to encode a previously inferred gene, gene X. Sequence analysis of a conditionally lethal amber mutation, am109, previously inferred to be located proximally in the secA gene, revealed that it was located distally in gene X and was conditionally lethal due to its polar effect on secA expression. This and additional evidence are presented indicating that gene X and secA are cotranscribed.
The predictive value of crossmatching platelet transfusion for alloimmunized patients (1985)

To determine the predictive value of a radiolabeled antiglobulin test for platelet crossmatching to select platelets for transfusion, we evaluated 230 transfusions in 42 alloimmunized oncology patients. Transfusions were classified according to the degree of HLA match. The value of the crossmatch in predicting platelet transfusion outcome was analyzed for each HLA category. For predicting the 1-hour corrected platelet count increment of all transfusions, the sensitivity of the test was 86 percent, specificity 84 percent, and total predictive value 84 percent. The crossmatch technique had similar predictive ability in all categories of HLA match, whether analyzing the results on the basis of the 1- or 24-hour platelet count rise.
Fumarate Regulation of Gene Expression in <i>Escherichia coli</i> by the DcuSR ( <i>dcuSR</i> Genes) Two-Component Regulatory System (1998)

In Escherichia coli the genes encoding the anaerobic fumarate respiratory system are transcriptionally regulated by C4-dicarboxylates. The regulation is effected by a two-component regulatory system, DcuSR, consisting of a sensory histidine kinase (DcuS) and a response regulator (DcuR). DcuS and DcuR are encoded by the dcuSR genes (previously yjdHG) at 93.7 min on the calculated E. coli map. Inactivation of the dcuR and dcuS genes caused the loss of C4-dicarboxylate-stimulated synthesis of fumarate reductase (frdABCD genes) and of the anaerobic fumarate-succinate antiporter DcuB (dcuB gene). DcuS is predicted to contain a large periplasmic domain as the supposed site for C4-dicarboxylate sensing. Regulation by DcuR and DcuS responded to the presence of the C4-dicarboxylates fumarate, succinate, malate, aspartate, tartrate, and maleate. Since maleate is not taken up by the bacteria under these conditions, the carboxylates presumably act from without. Genes of the aerobic C4-dicarboxylate pathway encoding succinate dehydrogenase (sdhCDAB) and the aerobic succinate carrier (dctA) are only marginally or negatively regulated by the DcuSR system. The CitAB two-component regulatory system, which is highly similar to DcuSR, had no effect on C4-dicarboxylate regulation of any of the genes.
An improved method for determining renal sufficiency using volume of distribution and weight from bolus 99mTc-DTPA, two blood sample, paediatric data (2006)

The best RSI from f(V, W) is RSI = 90.927gammaV(0.35283)W(-0.20185) and should detect mildly (14.1%) reduced renal sufficiency.
Cyclosporin A Induces Peritoneal Fibrosis and Angiogenesis during Chronic Peritoneal Exposure to a Glucose-Based, Lactate-Buffered Dialysis Solution in the Rat (2007)

CsA combined with exposure to dialysis solutions was associated with increased peritoneal fibrosis and angiogenesis.
Fault-Tolerant Memory Simulator (1984)

Memory systems in modern computers employ a variety of methods to achieve fault tolerance, such as single- or double-error correction, page deallocation, or the use of spare chips or cells. Such methods ensure that the failure rate of the system is considerably less than the sum of the failure rates of the components. However, these methods also complicate the task of evaluating system reliability. The memory reliability function is too intractable to handle analytically, and we must turn to Monte Carlo methods. This paper describes the Fault-Tolerant Memory Simulator (FTMS), an interactive APL program which uses Monte Carlo simulation to evaluate the reliability of fault-tolerant memory systems.
Adaptive synchronization and channel parameter estimation using an extended Kalman filter (1989)

Unified modeling and estimation of the MD (multiplicative distortion) in finite-alphabet digital communication systems is presented. A simple form of MD is the carrier phase exp(j theta ), which has to be estimated and compensated for in a coherent receiver. A more general case with fading must, however, allow for amplitude as well as phase variations of the MD. The authors assume a state-variable model for the MD and generally obtain a nonlinear estimation problem with additional randomly varying system parameters such as received signal power, frequency offset, and Doppler spread. An extended Kalman filter is then applied as a near-optimal solution to the adaptive MD and channel parameter estimation problem. Examples are given to show the use and some advantages of this scheme.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Turning Kids On To Language (1976)

One of the great problems we face as teachers is how to get kids interested in whatever it is that we want to teach them. Whether it is reading, writing, math, social studies, we know that the key to teaching success is motivation. “If we could just get them involved, we could teach them.” TURNING KIDS ON TO LANGUAGE
Simple Human Gesture Detection and Recognition Using a Feature Vector and a Real-Time Histogram Based Algorithm (2011)

Gesture and action recognition for video surveillance is an active field of computer vision. Nowadays, there are several techniques that attempt to address this problem by 3D mapping with a high computational cost. This paper describes software algorithms that can detect the persons in the scene and analyze different actions and gestures in real time. The motivation of this paper is to create a system for thetele-assistance of elderly, which could be used as early warning monitor for anomalous events like falls or excessively long periods of inactivity. We use a method for foreg-round-background segmentation and create a feature vectorfor discriminating and tracking several people in the scene. Finally, a simple real-time histogram based algorithm is described for discriminating gestures and body positions through a K-Means clustering.
The Political Demography of Think Tanks (2004)

The men of [the] Brookings [Institution] did it by analysis, by painstaking research, by objective writing, by an imagination that questioned the “going” way of doing things, and then they proposed alternatives. … After 50 years of telling the Government what to do, you are more than a private institution. … You are a national institution, so important … that if you did not exist we would have to ask someone to create you.President Lyndon B. Johnson September 29, 1966
Relative Contribution of Wall Shear Stress and Injury in Experimental Intimal Thickening at PTFE End-to-Side Arterial Anastomoses (2001)

The data are consistent with a model of intimal thickening in which the intimal hyperplastic pannus migrating from the suture line was enhanced by reduced levels of wall shear stress at the PTFE graft/host artery interface. Such hemodynamic modulation of injury induced IHT was absent at the neighboring artery wall.
Controlled fragrance delivery in functionalised ionic liquid-enzyme systems (2012)

It is often believed that both ionic liquids and surfactants generally behave as non-specific denaturants of proteins. In this paper, it is shown that amphiphilic ionic liquids bearing a long alkyl chain and a target molecule, where the target molecule is appended via a carboxylic ester functionality, can represent super-substrates that enable the catalytic activity of an enzyme, even at high concentrations in solution. Menthol has been chosen as the target molecule for slow and controlled fragrance delivery, and it was found that the rate of the menthol release can be controlled by the chemical structure of the ionic liquid. At a more fundamental level, this study offers an insight into the complex hydrophobic, electrostatic, and hydrogen bond interactions between the enzyme and substrate.
Inhibition of Sulfotransferases by Xenobiotics (2005)

The sulfotransferase (SULT) family comprises important phase II conjugation enzymes for the detoxification of xenobiotics and modulation of the activity of physiologically important endobiotics such as thyroid hormones, steroids, and neurotransmitters. SULT enzymes catalyze the transfer of a sulfuryl group, donated by 3'-phosphoadenosine-5'-phosphosulfate (PAPS), to an acceptor substrate that may be a hydroxy group or an amine group in a process originally called sulfation, but more correctly referred to as sulfonation or sulfurylation. SULT activity may be inhibited when humans are exposed to certain xenobiotics including drugs (mefenamic acid, salicylic acid, clomiphene, danazol etc.), dietary chemicals (catechins, food colorants, flavonoids and phytoestrogens etc.), and environmental chemicals (hydroxylated polychlorinated biphenyls, hydroxylated polyhalogenated aromatic hydrocarbons, pentachlorophenol, triclosan and bisphenol A, etc.). Inhibition of individual SULT isoforms may cause adverse effects on human health. For example, hydroxylated polychlorinated biphenyls have been shown to interfere with the transport of thyroid hormones, inhibit estradiol sulfonation, and inhibit thyroid hormone sulfonation, thereby potentially disrupting the thyroid hormone system. Formation of sulfate conjugates of toxic xenobiotics usually decreases their toxicity, so inhibition of this pathway may lead to prolonged exposure to the compounds. Conversely, some sulfate conjugates are chemically reactive, inhibition of their formation may protect from toxicity. This manuscript will review the literature concerning the inhibition of SULTs by xenobiotics including isoform-selective effects, inhibition kinetics and health effects resulting from the inhibition.
Yellow signal light timing and the dilemma zone. (1995)

The author comments on the timing of the yellow signal light. He is especially concerned about accidents in intersections which may be caused by the lack of sufficient response time to the yellow signal light, the worsening of this situation when other conditions such as wet pavement or downgrades exist, and the lack of markings to indicate where the dilemma zone is when the signal light turns yellow. He makes recommendations for improving the current situation and eliminating the present highway signs warning of signals ahead, the primary function of which appears to be to warn the public that the traffic signal ahead is not properly designed for this highway and the state wishes to disclaim any responsibility for the accidents that will occur.
Numerical Optimal Control of Wave Energy Converters (2014)

Energy maximizing control for wave energy converters (WECs) is a nonstandard optimal control problem. While the constrained optimal control problem for WECs has been addressed by model-predictive control strategies, such strategies need to employ cost function modifications due to convexity problems and the algorithms are computationally complex, making real-time implementation difficult. The recently developed family of direct transcription methods offer a promising alternative, since they are computationally efficient and a convex problem results. Moreover, constraints on both the device displacement and velocity, and power take off force, are easily incorporated. Both single-body and multibody device models can be used, as well as arrays of single-body or multibody devices.
Routes to mitomycins. Chirospecific synthesis of aziridinomitosenes (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRoutes to mitomycins. Chirospecific synthesis of aziridinomitosenesKenneth J. Shaw, Jay R. Luly, and Henry RapoportCite this: J. Org. Chem. 1985, 50, 23, 4515–4523Publication Date (Print):November 1, 1985Publication History Published online1 May 2002Published inissue 1 November 1985https://pubs.acs.org/doi/10.1021/jo00223a019https://doi.org/10.1021/jo00223a019research-articleACS PublicationsRequest reuse permissionsArticle Views1431Altmetric-Citations123LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Interactive recognition of handprinted characters for computer input (1986)

Recent development in real-time recognition of handprinted characters have resulted in a commercial device that reads "unconstrained," or free-form, handprinting. Unlike most devices that optically read machineprinted characters in finished text, this device is suitable for interactive system: It reads from a digitizing tablet while the user is writing.
<i>In vivo</i> measurement of nitric oxide production in porcine gut, liver and muscle during hyperdynamic endotoxaemia (2002)

1. During prolonged endotoxaemia, an increase in arginine catabolism may result in limiting substrate availability for nitric oxide (NO) production. These effects were quantitated in a chronically instrumented porcine endotoxaemia model. 2. Ten days prior to the beginning of the experiments, pigs were catheterized. On day 0, pigs received a continuous infusion of endotoxin (3 microg kg(-1) h(-1)) over 24 h and were saline resuscitated. Blood was drawn from the catheters at 0 and 24 h during primed-infusion of (15)N(2)-arginine and P-aminohippurate to assess (15)N(2)-arginine to (15)N-citrulline conversion and plasma flow rates, respectively, across the portal-drained viscera, liver and hindquarter. 3. During endotoxin infusion a hyperdynamic circulation with elevated heart rate, cardiac index and decreased mean arterial pressure was achieved, characteristic of the human septic condition. 4. Endotoxin induced NO production by the portal-drained viscera and the liver. The increased NO production was quantitatively matched by an increase in arginine disposal. Nitrite/nitrate levels remained unchanged during endotoxaemia. 5. Despite an increased arginine production from the hindquarter and an increased whole-body arginine appearance rate during endotoxin infusion, the plasma arginine concentration was lower in endotoxin-treated animals than in controls. 6 On a whole-body level, the muscle was found to serve as a major arginine supplier and, considering the lowered arginine plasma levels, seems critical in providing arginine as precursor for NO synthesis in the splanchnic region.
Endothelial progenitor cells in angiogenesis. (2005)

Circulating blood contains a subtype of progenitor cells that have the capacity to differentiate into mature endothelial cells in vitro and in vivo. These cells have been termed endothelial progenitor cells (EPCs). The isolation of EPCs by adherence culture or magnetic microbeads has been described. EPCs are characterized by the expression of 3 markers, CD133, CD34, and the vascular endothelial growth factor receptor-2. After differentiation, EPCs express CD31, vascular endothelial cadherin, and von Willebrand factor. Evidence is accumulating that EPCs can facilitate endothelial repair and angiogenesis in vivo. We observed that EPCs can regenerate damaged endothelial cells in vascular grafts in apoE-deficient mice, and that abundant vascular progenitor cells are present in the adventitia of the vessel wall. It is not clear yet, however, whether these EPCs are essential for these angiogenic and atherogenic processes. Moreover, there are still many uncertainties about how cardiovascular risk factors alter EPC function. Thus, further studies on the mechanisms of EPC homing, releasing and attaching will be of help to explore areas of potential basic research and clinical application of EPCs.
<i>Encyclopedia of Materials Science and Engineering</i> (1987)

This major eight-volume reference work provides the first unified treatment of an important interdisciplinary field.
0.3- mu m advanced SAINT FET's having asymmetric n/sup +/-layers for ultra-high-frequency GaAs MMIC's (1988)

Improvements in the microwave performance and noise performance of buried p-layer self-aligned gate (BP-SAINT) FETs are discussed. Specifically, a self-aligned gate electrode and an asymmetric n/sup +/-layer structure are investigated. The self-aligned gate electrode reduces parasitic gate capacitances by 0.13 to 0.23 pF/mm compared with a conventional BP-SAINT FET. The asymmetric n/sup +/-layer structure reduces short-channel effects (drain conductance, threshold voltage shift, etc.) and gate-drain capacitance. A 0.3- mu m gate-length FET was realized without an increase of short-channel effects by using an asymmetric n/sup +/-layer structure (advanced SAINT). Improvement of microwave performance is confirmed in this FET structure.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Organophosphorus Acid Anhydride Hydrolase Activity in Human Butyrylcholinesterase:  Synergy Results in a Somanase (1998)

Organophosphorus acid anhydride (OP) "nerve agents" are rapid, stoichiometric, and essentially irreversible inhibitors of serine hydrolases. By placing a His near the oxyanion hole of human butyrylcholinesterase (BChE), we made an esterase (G117H) that catalyzed the hydrolysis of several OP, including sarin and VX [Millard et al. (1995) Biochemistry 34, 15925-15930]. G117H was limited, however, because it was irreversibly inhibited by pinacolyl methylphosphonofluoridate (soman); soman is among the most toxic synthetic poisons known. This limitation of G117H has been overcome by a new BChE (G117H/E197Q) that combines two engineered features: spontaneous dephosphonylation and slow aging (dealkylation). G117H/E197Q was compared with the single mutants BChE G117H and E197Q. Each retained cholinesterase activity with butyrylthiocholine as substrate, although kcat/Km decreased 11-, 11- or 110-fold for purified G117H, E197Q, or G117H/E197Q, respectively, as compared with wild-type BChE. Only G117H/E197Q catalyzed soman hydrolysis; all four soman stereoisomers as well as sarin and VX were substrates. Phosphonylation and dephosphonylation reactions were stereospecific. Double mutant thermodynamic cycles suggested that the effects of the His and Gln substitutions on phosphonylation were additive for PSCR or PRCR soman, but were cooperative for the PSCS stereoisomer. Dephosphonylation limited overall OP hydrolysis with apparent rate constants of 0.006, 0.077, and 0.128 min-1 for the PR/SCR, PSCS, and PRCS soman stereoisomers, respectively, at pH 7.5, 25 degrees C. We conclude that synergistic protein design converted an archetypal "irreversible inhibitor" into a slow substrate for the target enzyme.