gebhart/patrepeval huggingface dataset:
The Gas Liquid Interface and the Load Capacity of Helical Grooved Journal Bearings (1973)

Self-acting helical-grooved journal bearings, lubricated by an incompressible Newtonian liquid and operating under laminar conditions, have under favorable conditions a negligible leakage due to the inward pumping action of the grooves. During concentric running, the axial position of the gas liquid interface created in the grooved section of the bearing does not vary in circumferential direction (local effects due to a finite number of grooves are not taken into account). During eccentric running, however, the width of the liquid region, i.e., the interface varies in circumferential direction due to pressure differences in the lubricant film. For a complete herringbone journal bearing the interaction between the shape of the interface and the pressure distribution has been studied both theoretically and experimentally.
An optimized location-based mobile restaurant recommend and navigation system (2009)

Abstract:-With the widely used of the intelligent mobile phones with the GPS, the location-based services has become the a hot issue of mobile communications research. This paper implements a Mobile Location-based Restaurant Navigation and Recommend System. In order to improve server-side response speed for real-time query, we propose a memory pool model, the expansion Accept command, no-data client polling and interrupt mechanism, which aims to greatly optimize the server-side control procedures. On the client side, we combine the latest Web2.0 application data with the location-based data, and propose a collaborative assessment and recommend mechanisms, which can provide users with real-time location-based restaurant and recommend personalized navigation.
<b>Organic Sulfur Compounds. VIII. Addition of Thiols to Conjugated Diolefins</b> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic Sulfur Compounds. VIII. Addition of Thiols to Conjugated DiolefinsAlexis A. Oswald, Karl. Griesbaum, Warren A. Thaler, and B. E. HudsonCite this: J. Am. Chem. Soc. 1962, 84, 20, 3897–3904Publication Date (Print):October 1, 1962Publication History Published online1 May 2002Published inissue 1 October 1962https://pubs.acs.org/doi/10.1021/ja00879a020https://doi.org/10.1021/ja00879a020research-articleACS PublicationsRequest reuse permissionsArticle Views405Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Expression cloning in yeast of a cDNA encoding a broad specificity amino acid permease from Arabidopsis thaliana. (1993)

To study amino acid transport in plants at the molecular level, we have isolated an amino acid permease cDNA from Arabidopsis thaliana by complementation of a yeast mutant defective in proline uptake with a cDNA. The predicted polypeptide of 53 kDa is highly hydrophobic with 12 putative membrane-spanning regions and shows no significant homologies to other known transporters. Expression of the cDNA enables the yeast mutant to take up L-[14C]proline. Competition studies argue for a broad but stereospecific substrate recognition by the permease, which resembles neutral or general amino acid transport systems from Chlorella and higher plants. Both pH dependence and inhibition by protonophores are consistent with a proton symport mechanism.
Struktur der Sesquiterpene von <i>Petasites hybridus</i> (<scp>L.</scp>) <scp>G. M.</scp><i>et</i> SCH.: Petasol‐ und Isopetasol‐Abkömmlinge (1979)

Structure of the Sesquiterpenes of Petasites hybridus ( L. ) G. M. et SCH .: Petasol and Isopetasol Derivatives The structure of 11 compounds of the sesquiterpene fraction of petasites hybridus has been determined by combination of spectroscopic methods, especially by analysis of the 360‐MHz‐ 1 H‐NMR. spectra. Most natural products are esters of two isomeric sesquiterpene alcohols, characterized by an eremophilan skeleton, namely of petasol as well as of isopetasol . The structure of one key product has been confirmed by X‐ray analysis.
Genome Engineering of <i>Eubacterium limosum</i> Using Expanded Genetic Tools and the CRISPR-Cas9 System (2019)

<i>Eubacterium limosum</i> is one of the important bacteria in C<sub>1</sub> feedstock utilization as well as in human gut microbiota. Although <i>E. limosum</i> has recently garnered much attention and investigation on a genome-wide scale, a bottleneck for systematic engineering in <i>E. limosum</i> is the lack of available genetic tools and an efficient genome editing platform. To overcome this limitation, we here report expanded genetic tools and the CRISPR-Cas9 system. We have developed an inducible promoter system that enables implementation of the CRISPR-Cas9 system to precisely manipulate target genes of the Wood-Ljungdahl pathway with 100% efficiency. Furthermore, we exploited the effectiveness of CRISPR interference to reduce the expression of target genes, exhibiting substantial repression of several genes in the Wood-Ljungdahl pathway and fructose-PTS system. These expanded genetic tools and CRISPR-Cas9 system comprise powerful and widely applicable genetic tools to accelerate functional genomic study and genome engineering in <i>E. limosum</i>.
Crystal structure of ettringite (1969)

ETTRINGITE (Ca6[Al(OH)6]2(SO4)3.26H2O) occurs as a natural mineral, and is technically important as a hydration product of Portland and supersulphated cements and in its use, as satin white, for coating paper. It forms hexagonal, prismatic crystals which in synthetic material are often highly elongated. Bannister, Hey and Bernal1 obtained unit-cell data (hexagonal: a 11.26, c 21.48 A, space group P63/mmc, Z = 2). No crystal structure determination based on single crystal evidence has been reported, but Welin2 determined the structure of a related mineral, thaumasite (Ca6H4(SiO4)2(SO4)2(CO3)2.26H2O), which he found to be based on chains of Ca2+ and SiO44− ions with the remaining ions and water molecules in between.
Role of Endothelial Nitric Oxide Synthase as a Trigger and Mediator of Isoflurane-induced Delayed Preconditioning in Rabbit Myocardium (2005)

The results suggest that endothelial NOS but not inducible or neuronal NOS is a trigger and mediator of delayed preconditioning by isoflurane in vivo.
Detection of application layer DDoS attack with clustering and likelihood analysis (2013)

One of the attacks observed against HTTP protocol is HTTP-GET attack using sequences of requests to limit accessibility of webservers. This attack has been researched in this report, and a novel detection technique has been developed to tackle it. In general, the technique uses entropy-based clustering and application of likelihood analysis to distinguish among legitimate and attacking sequences. It has been presented that the introduced method allows for formation of recent patterns of behaviours observed at a webserver, that remain unknown to the attackers. In addition, empirical analysis shows stability of the clustering approach. Subsequently, likelihood of websession behaviour has been provided to measure anomaly of web sessions. The method performs reasonably well, regardless of browsing strategies and scope chosen by attackers.
Crossover between multipole Coulomb and Kubas interactions in hydrogen adsorption on metal-graphene complexes (2009)

The hydrogen adsorption on alkaline-earth metal dispersed in doped graphenes was studied through ab initio calculations. Substitutional doping in graphenes is explored to control the ionic state of the metal atoms that plays a crucial role for dispersion and hydrogen adsorption. It was found that the adsorption behavior, particularly in Ca-dispersed graphene complexes, exhibits a crossover between the multipole Coulomb and Kubas-type (or orbital) interactions as the ionic state of Ca and the number of adsorbed hydrogen molecules change. The level exchange in $s$ and $d$ orbitals of Ca is responsible for the crossover. This finding enables the optimization of hydrogen adsorption and metal dispersion in graphitic materials, which is useful for developing solid hydrogen storage and efficient catalysts.
Two Classroom Exercises Demonstrating the Pattern of Container Soil Water Distribution1 (1974)

Abstract The soil water distribution pattern in a container soil is simulated using cellulose sponges as an analog of container soils. Two classroom exercises are presented that have been successful in both classroom and extension presentations to horticulturists.
Fast Omnidirectional 3D Scene Acquisition with an Array of Stereo Cameras (2007)

We present an omnidirectional 3D acquisition system based on a mobile array of high-resolution consumer digital SLR cameras that automatically capture high dynamic range stereo pairs across a full 360-degree panorama. The stereo pairs are augmented with a time-varying lighting pattern created using standard photographic flashes, lenses, and patterned slides. Spacetime stereo techniques are used to generate 3D range images with corresponding color data from the HDR photographs. The multiple range images are aligned with egomotion estimation and ICP registration techniques, and volumetric merging and color texturing algorithms allow the rapid creation of complete 3D models. The resulting system compares favorably with other state of the art 3D acquisition technologies in the resolution and quality of its output, and can be faster and less expensive than 3D laser scanners for digitizing large 3D scenes such as building interiors.
Ultrafast All-Optical Switching in a Silicon-Nanocrystal-Based Silicon Slot Waveguide at Telecom Wavelengths (2010)

We demonstrate experimentally all-optical switching on a silicon chip at telecom wavelengths. The switching device comprises a compact ring resonator formed by horizontal silicon slot waveguides filled with highly nonlinear silicon nanocrystals in silica. When pumping at power levels about 100 mW using 10 ps pulses, more than 50% modulation depth is observed at the switch output. The switch performs about 1 order of magnitude faster than previous approaches on silicon and is fully fabricated using complementary metal oxide semiconductor technologies.
Highly stable, dual-port, sub-threshold 7T SRAM cell for ultra-low power application (2012)

As the supply voltage is reducing with feature size, SRAM cell design is going through severe stability issues. The issue becomes worse due to increased variability in below sub-100nm technology. In this paper, we present a highly stable 2-port 7T SRAM cell for ultra-low power in 90nm technology. The dynamic read noise margin is improved by 7X over conventional dual port SRAM. Finally, a 4Kb bit-interleaved SRAM architecture is presented using proposed cell. Experimental results show that memory consumes 1.26pJ/bit at 0.22V supply voltage with 2MHz performance. The dynamic read noise margin is improved by 7X over conventional dual port SRAM. The successful write and read operations can be performed at supply voltage as low as 0.17V. Two level write decoder architecture is used to eliminate the pseudo read problem in unselected columns.
Relevance of volume and proximal extent of reflux in gastro-oesophageal reflux disease (2005)

In patients with gastro-oesophageal reflux disease (GORD), oesophageal and extraoesophageal symptoms are traditionally attributed to increased contact time between the mucosa and refluxates. However, the volume of reflux may be important by increasing the total amount of highly concentrated damaging substances, either by prolonging distal mucosal exposure or by expanding to more proximal areas. To date, it has not been possible to accurately measure the volume of gastro-oesophageal reflux. Determination of the volume of reflux will help to better understand the pathophysiology of GORD and to evaluate the efficacy of antireflux treatments.
Reaction of Carbon Anions With Iron α,β‐Unsaturated Ketimine Complexes (1988)

Abstract Complexes (η 4 ‐PhCH=CHCR=NPh)Fe(CO) 3 , where R=H(1a) and CH 3 were synthesized in excellent yield from the reaction of the corresponding α,β‐unsaturated ketimines with excess Fe 2 (CO) 9 . Reaction of la with (Ph) 2 CHLi and (CH 3 ) 2 (NC)CLi at −78°C or ambient temperature followed by acid quenching gave trans ‐PhCH=CHCHRNHPh, where R=CHPH 2 and C(CH 3 ) 2 CN, respectively, in good yield. In the presence of 1 atm. of CO the reaction of 1a with (CH 3 ) 2 (NC)CLi, followed by CuCl 2 oxidation resulted in the formation of a carbamyl choride, trans ‐PhCH=CHCH[C(CH 3 ) 2 CN]N(Ph)COCl. This species was converted to a carbamate compound trans ‐PhCH=CHCH[C(CH 3 ) 2 ‐ CN]N(Ph)COOCH 3 in MeOH in the presence of Ag + .
Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1 (2013)

The Hippo signaling pathway inhibits cell growth and regulates organ size through a kinase cascade that leads to the phosphorylation and nuclear exclusion of the growth-promoting transcriptional coactivator Yes-associated protein (YAP)/Yorkie. It mediates contact inhibition of cell growth downstream of cadherin adhesion molecules and other cell surface proteins. Contact inhibition is often antagonized by mitogenic growth factor signaling. We report an important mechanism for this antagonism, inhibition of Hippo pathway signaling by mitogenic growth factors. EGF treatment of immortalized mammary cells triggers the rapid translocation of YAP into the nucleus along with YAP dephosphorylation, both of which depend on Lats, the terminal kinase in the Hippo pathway. A small-molecule inhibitor screen of downstream effector pathways shows that EGF receptor inhibits the Hippo pathway through activation of PI3-kinase (PI3K) and phosphoinositide-dependent kinase (PDK1), but independent of AKT activity. The PI3K-PDK1 pathway also mediates YAP nuclear translocation downstream of lysophosphatidic acid and serum as a result of constitutive oncogenic activation of PI3K. PDK1 associates with the core Hippo pathway-kinase complex through the scaffold protein Salvador. The entire Hippo core complex dissociates in response to EGF signaling in a PI3K-PDK1-dependent manner, leading to inactivation of Lats, dephosphorylation of YAP, and YAP nuclear accumulation and transcriptional activation of its target gene, CTGF. These findings show that an important activity of mitogenic signaling pathways is to inactivate the growth-inhibitory Hippo pathway and provide a mechanism for antagonism between contact inhibition and growth factor action.
Plasmid transfer and genetic recombination by protoplast fusion in staphylococci (1981)

The experimental conditions for plasmid transfer and genetic recombination in Staphylococcus aureus and some coagulase-negative staphylococci by protoplast fusion are described. Protoplasts were prepared by treatment with lysostaphin and lysozyme in a buffered medium with 0.7 to 0.8 M sucrose. Regeneration of cell walls was accomplished on a hypertonic agar medium containing succinate and bovine serum albumin. Transfer of plasmids occurred after treatment of the protoplast mixtures with polyethylene glycol (molecular weight, 6,000) not only between strains of the same species but also between parents of different species, although at approximately 100 times lower frequency in the latter case. Recombination of the chromosomal genes in fused protoplasts required simultaneous treatment of the mixed protoplasts with polyethylene glycol and CaCl2. A method was developed for isolation of recombinants after fusion between mutants of S. areus carrying unselectable markers. Antibiotic resistance plasmids were introduced into the parental strains and used as primary markers to detect protoplast fusion. Chromosomal recombinants were found among the clones with both parental plasmids at a high frequency. The method appears to have simple applications in the construction of strains with multiple mutant characters.
Plasticity and expanding complexity of the hepatic transcription factor network during liver development (2006)

Cross-regulatory cascades between hepatic transcription factors have been implicated in the determination of the hepatic phenotype. Analysis of recruitments to regulatory regions and the temporal and spatial expression pattern of the main hepatic regulators during liver development revealed a gradual increase in complexity of autoregulatory and cross-regulatory circuits. Within these circuits we identified a core group of six transcription factors, which regulate the expression of each other and the expression of other downstream hepatic regulators. Changes in the promoter occupancy patterns during development included new recruitments, release, and exchange of specific factors. We also identified promoter and developmental stage-specific dual regulatory functions of certain factors as an important feature of the network. Inactivation of HNF-4alpha in embryonic, but not in adult, liver resulted in the diminished expression of most hepatic factors, demonstrating that the stability of the network correlates with its complexity. The results illustrate the remarkable flexibility of a self-sustaining transcription factor network, built up by complex dominant and redundant regulatory motifs in developing hepatocytes.
An Efficient Implementation of the Generalized Labeled Multi-Bernoulli Filter (2016)

This paper proposes an efficient implementation of the generalized labeled multi-Bernoulli (GLMB) filter by combining the prediction and update into a single step. In contrast to an earlier implementation that involves separate truncations in the prediction and update steps, the proposed implementation requires only one truncation procedure for each iteration. Furthermore, we propose an efficient algorithm for truncating the GLMB filtering density based on Gibbs sampling. The resulting implementation has a linear complexity in the number of measurements and quadratic in the number of hypothesized objects.
2-phase optimization method for energy aware scheduling of virtual machines in cloud data centers (2011)

Need for computational power grows faster and faster so that we have “Cloud Computing” concept emerged from this need. In the other hand with growing popularity of computing and communication, request for more energy power increases and area of Green Computing try to moderate this procedure with revising old computing method or inventing new method to have more efficient computing material that would work more while consuming less energy and making less pollution. In this paper, the researchers tried to reduce energy consumed in Cloud computing datacenters by revising virtual machines scheduling method while keeping quality of service parameters as high as possible. We implemented our approach using CloudSim toolkit and evaluated it in compare with recent popular methods. Evaluation result demonstrates our success in reaching our aims to reduce energy consumption while keeping quality of service in acceptable range by reduction in number of virtual machines migrations.
Identification of Canine Transmissible Venereal Tumor Cells Using in Situ Polymerase Chain Reaction and the Stable Sequence of the Long Interspersed Nuclear Element (2003)

Canine transmissible venereal tumor (CTVT) is a unique tumor that can be transplanted across the major histocompatibility complex (MHC) barrier by viable tumor cells. In dogs, CTVT grows progressively for a few months and then usually regresses spontaneously. A long interspersed nuclear element (LINE) insertion is found specifically and constantly in the 5' end of the CTVT cell c-myc gene, outside the first exon. The rearranged LINE-c-myc gene sequence has been used with polymerase chain reaction (PCR) to diagnose CTVT. However, in CTVT cells, the total length of the inserted LINE gene is not constant. In this experiment, variation in the inserted LINE gene was studied to determine which parts of the LINE sequence can be used as primers to identify CTVT cells with in situ PCR (IS PCR). The LINE gene was inserted between the TATA boxes in the promoter region of c-myc. In CTVT cells, deletions of different lengths are frequent in this gene. However, the 550-bp segment at the 5' end of the LINE-c-myc gene was stable. Thus, primers were designed to cover the stable 0.55-kb segment from the 5' end outside the first exon of the c-myc gene to the 5' end of LINE gene stable segment. With these primers and IS PCR, individual CTVT cells in formalin-fixed tissue sections and CTVT cultures were identified. Cells from other canine tumors were negative for this gene. In addition, the CTVT-specific, 0.55-kb segment was not found in any spindle-shaped cells from progressive or regressive phase CTVT. The IS PCR technique also did not detect any positive spindle-shaped cells in CTVT cell cultures. Thus, fibroblastic terminal differentiation is less likely to be a mechanism for spontaneous regression of CTVT cells.
Effect of Helium in Helium Headspace Carbon Dioxide Cylinders on Packed-Column Supercritical Fluid Chromatography (1996)

Supercritical fluid chromatography of PAHs was performed with pure carbon dioxide and helium headspace carbon dioxide at various cylinder fill levels. The retention times of the PAHs increased when helium headspace carbon dioxide was used as a carrier fluid relative to pure carbon dioxide. The increased retention times were affected by the level of the liquid phase present in the helium headspace carbon dioxide cylinder. As more liquid phase was removed from the cylinder, the effect of helium on the solvating power of CO(2) was reduced because the relative amount of helium dissolved in the liquid phase decreased. Furthermore, the effect of helium headspace carbon dioxide was investigated with methanol-modified carbon dioxide mobile phases for the analysis of steroids. We observed that the relative solubility of helium in carbon dioxide resulted in longer retention times when compared to pure carbon dioxide as the liquid level of carbon dioxide decreased.
Human Post‐thymic Precursor Cells in Health and Disease (1981)

Adult peripheral blood T lymphocytes activated in autologous mixed lymphocyte reactions (AMLR) exerted cytotoxicity on both phytohaemagglutinin-stimulated cells and Epstein-Barr virus-transformed cells. When autologous rosette-forming T cells were removed from total T lymphocytes, there was no generation of cytotoxicity. Re-addition of autologous rosette-forming T cells (Tar cells) to a population of T cells depleted of Tar cells restored the cytotoxic activity. Treatment of Tar cells with mitomycin C before their activation in AMLR caused loss of their capacity to give rise to killer cells. Furthermore, resting Tar cells did not show any cytotoxic activity as determined in the two different types of target cells used. Since Tar cells are able to differentiate into T gamma cells and since T gamma cells possess spontaneous cytotoxic activity, it is likely that Tar cells participate in the generation of spontaneous killer cells in AMLR as precursors of cytotoxic effector cells.
Receptor Activation and Inositol Lipid Hydrolysis in Neural Tissues (1987)

Peer Reviewed