gebhart/patrepeval huggingface dataset:
Identification of a novel type 2 fiber population in mammalian skeletal muscle by combined use of histochemical myosin ATPase and anti-myosin monoclonal antibodies. (1990)

A novel type of myosin heavy chain (MHC), called 2X, has been recently identified in type 2 fibers of rat skeletal muscles using an immunochemical approach. In the present study, the same panel of anti-MHC monoclonal antibodies was used in immunohistochemistry combined with enzyme histochemistry to identify and compare type 2X fibers in hindlimb skeletal muscles of rat, mouse, and guinea pig. Immunohistochemistry shows that 2X MHC is localized in a large subset of type 2 fibers and is co-expressed with 2A or 2B MHC in a small number of fibers. Enzyme histochemistry shows that type 2X fibers display low myosin ATPase activity after pre-incubation at pH 4.3 and high activity after paraformaldehyde pre-incubation at pH 10.4. After pre-incubation at pH 4.6, myosin ATPase shows intermediate and high activity in rat and mouse 2X fibers, respectively, whereas it is low in guinea pig 2X fibers. Succinate dehydrogenase displays moderate to high activity in 2X fibers of all species. Taken together, these staining patterns allow this novel fiber population to be distinguished from the other type 2 fibers using only enzyme histochemistry. Nevertheless, the combined use of immuno- and enzyme histochemistry prevents incorrect fiber typing due to the interspecies variability of myosin ATPase activity among the correspondent fiber types, and completely modifies the presently used classification of mouse type 2 fibers.
Pref Shop A Web Shop with User Preference Search Capabilities (2010)

The main topic of this paper is description of a proposal of a web shop with user preference searching - PrefShop. A typical web shop was implemented, but new capabilities were added to help the user with finding desired object. Besides preference search, visual hints that clarify the object relevance or the lack of relevance are proposed.
Single coronary artery: circumflex/right coronary circle (2007)

A 70-year-old woman with a background history of hypertension and hypercholesterolaemia presented with an anterior myocardial infarction. She received thrombolytic treatment, with …
Systemic Lupus Erythematosus and Monoclonal Gammopathy (1988)

Journal Article Systemic Lupus Erythematosus and Monoclonal Gammopathy Get access J FONT, J FONT Servicio de Medicina Interna General Hospital, Clfnico y Provincial, Universidad de BarcelonaSpain Search for other works by this author on: Oxford Academic PubMed Google Scholar L. CERVERA, L. CERVERA Servicio de Medicina Interna General Hospital, Clfnico y Provincial, Universidad de BarcelonaSpain Search for other works by this author on: Oxford Academic PubMed Google Scholar L. PALLARES, L. PALLARES Servicio de Medicina Interna General Hospital, Clfnico y Provincial, Universidad de BarcelonaSpain Search for other works by this author on: Oxford Academic PubMed Google Scholar A. LOPEZ-SOTO, A. LOPEZ-SOTO Servicio de Medicina Interna General Hospital, Clfnico y Provincial, Universidad de BarcelonaSpain Search for other works by this author on: Oxford Academic PubMed Google Scholar L. INGELMO L. INGELMO Servicio de Medicina Interna General Hospital, Clfnico y Provincial, Universidad de BarcelonaSpain Search for other works by this author on: Oxford Academic PubMed Google Scholar Rheumatology, Volume 27, Issue 5, October 1988, Page 412, https://doi.org/10.1093/rheumatology/27.5.412 Published: 01 October 1988 Article history Received: 03 June 1988 Published: 01 October 1988
Pressure‐Driven Assembly of Spherical Nanoparticles and Formation of 1D‐Nanostructure Arrays (2010)

Unter Druck wurden Nanopartikelanordnungen erzwungen. Durch reversible Änderung der Elementarzellparameter in einer Nanopartikelpackung mit 3D-Ordnung unter hydrostatischem Druck gelingt es, die Abstände zwischen den Partikeln genau einzustellen. Druckanwendung in einer Richtung brachte die Nanopartikel in Kontakt, sodass sie sich zu dicht gepackten Nanostäben oder -drähten zusammenlagerten (siehe Bild; kleine Pfeile deuten die Druckanwendung an).
Effects of Extra 5' Non-Viral Bases on the Infectivity of Transcripts from a cDNA Clone of Satellite RNA (Strain Y) of Cucumber Mosaic Virus (1988)

Full-length cDNA of a satellite RNA (Strain Y) which induces bright yellow symptoms on tobacco plants infected with cucumber mosaic virus (CMV) was cloned and sequenced. The published sequence of the satellite RNA was revised with three possible differences (residues 161, 167, and 173) and a nucleotide insertion at residue 234. The satellite cDNA was then inserted into a commercially available transcription vector. In vitro transcription products from the recombinant plasmid harbored 24 non-viral bases at their 5' ends and had very low infectivity when coinoculated with CMV. After removal of the extra 5' sequence of the transcripts with RNase H, the infectivity of the transcripts increased markedly. Analysis of the effects of extra 5' sequences of several lengths confirmed the importance of natural 5' ends for biological activity of the satellite. Trimming down to 6-9 extra bases at the 5' end enhanced the infectivity of the transcripts by 10-fold, although the specific activity of the natural satellite is still 100-fold higher. Dideoxynucleotide sequence analysis proved that the progeny satellite RNA did not retain the 24 non-viral bases at the 5' end of the transcript from pIBI 31-MC.
Thermal desorption characteristics of CO, O2 and CO2 on non-porous water, crystalline water and silicate surfaces at submonolayer and multilayer coverages (2012)

The desorption characteristics of molecules on interstellar dust grains are important for modelling the behaviour of molecules in icy mantles and, critically, in describing the solid–gas interface. In this study, a series of laboratory experiments exploring the desorption of three small molecules from three astrophysically relevant surfaces is presented. The desorption of CO, O2 and CO2 at both submonolayer and multilayer coverages was investigated from non-porous water, crystalline water and silicate surfaces. Experimental data were modelled using the Polanyi–Wigner equation to produce a mathematical description of the desorption of each molecular species from each type of surface, uniquely describing both the monolayer and multilayer desorption in a single combined model. The implications of desorption behaviour over astrophysically relevant time-scales are discussed.
Local sound field reproduction using two closely spaced loudspeakers (1998)

When only two loudspeakers are used for the reproduction of sound for a single listener, time domain simulations show that it is advantageous that the two loudspeakers are very close together. The sound field reproduced by two loudspeakers that span 10 degrees as seen by the listener is simpler, and locally more similar to the sound field generated by a real sound source, than that reproduced by two loudspeakers that span 60 degrees. The basic physics of the problem is first explained by assuming that the sound propagates under free-field conditions. It is then demonstrated that when the influence of the listener on the incident sound waves is taken into account by modeling the listener’s head as a rigid sphere, the results are qualitatively the same as in the free-field case. Consequently, two closely spaced loudspeakers are capable of accurately reproducing a desired sound field, not only at the ears of the listener but also in the vicinity of the listener’s head. This result, although counter-intuitive, is very encouraging. In particular, it suggests that many low-fidelity audio systems, such as those currently supplied with most multi-media computers, can be greatly improved.
Effect of the resin/hardener ratio on curing, structure and glass transition temperature of nanofilled epoxies (2011)

Abstract The curing reaction, structure, and glass transition behavior of epoxy‐clay nanocomposites prepared using several different resin/hardener ratios were investigated. Nonisothermal DSC experiments evidenced that the incorporation of the organoclay did not induce appreciable changes in the curing enthalpy, but determined a slight acceleration of the curing reaction, without modifying the activation energy. TEM and SEM analyses of the nanocomposite resins showed the presence of micrometric aggregates for all the resin/hardener ratios investigated, even though these materials showed good optical clarity and their WAXD analyses did not evidence any organoclay peak. In addition, the higher the hardener content, the lower the tendency toward exfoliation and the broader the distribution of the interlamellar distances. The degree of cross‐linking of cured resins was evaluated both from measurements of the elastic modulus in the rubbery plateau and from solvent sorption experiments. A maximum in cross‐link density was observed near the stoichiometric composition. Both modulus and sorption experiments suggested that filler‐matrix adhesion increased with increasing the resin/hardener ratio, a trend that was confirmed also by glass transition temperature data. An analysis of ethyl acetate sorption curves evidenced that a gradual transition from Fickian to Case II diffusion occurred as the resin/hardener ratio was raised and that the organoclay promoted deviation from the Fickian behavior. POLYM. COMPOS., 2011. © 2011 Society of Plastics Engineers
Synthesis of Fluorine Analogs of Vitamin E. IV. Synthesis of Bis(trifluoromethyl)tocopherols. (1995)

We previously synthesized mono(trifluoromethyl)tocopherols, which were used for investigation of the mobility and orientation of tocopherol in Iliposomes by 19F-NMR. For more precise investigation of the behavior of vitamin E in liposomes, tocopherols having two trifluoromethyl groups, one on the prenyl side chain and the other on the chromanol ring, were synthesized. Thusn, dimethylhydroquinones were treated with 6-chloro-3-methyl-2-hexenol in the presence of zinc chloride to give 2-(3-chloropropyl)trimethylchromanol derivatives. These were converted to phosphonium salts, which, upon condensation with trifluoromethylated ketones followed by hydrogenation, gave tocopherols with a trifluoromethyl group on the side chain and a hydrogen on the chromanol part. These were halogenated on the chromanol part and treated with trifluoromethyl iodide and copper powder to give the title compounds.
Kinetic properties of the glycine receptor main‐ and sub‐conductance states of mouse spinal cord neurones in culture. (1991)

1. The kinetic properties of the two most frequent conductance states of glycine receptor channels from somata of mouse spinal cord neurones in cell culture were investigated using the outside-out patch clamp technique. At low concentrations of glycine (0.5, 1 and 2 microM), single-channel currents were recorded with two predominant amplitudes corresponding to a dominant or main-conductance state of about 42 pS and a sub-conductance state of about 27 pS. Both conductance states opened singly and in bursts of several openings. Total current evoked and single-channel opening frequency increased as glycine concentration was increased from 0.5 to 2 microM. 2. For both conductance states mean open times were increased and open time frequency histograms were shifted to longer times as glycine concentration was increased from 0.5 to 2 microM. For both conductance states, three exponential components were required to fit best open time frequency distribution histograms at all glycine concentrations (0.5, 1 and 2 microM). The time constants of the exponential components for each conductance state were not significantly different across concentration, suggesting that the main- and sub-conductance states of the channel each opened into at least three open states. For the main-conductance state, the time constants were 1.09 +/- 0.09, 4.06 +/- 0.26 and 9.79 +/- 0.30 ms. For the sub-conductance state, the time constants were 0.55 +/- 0.04, 2.64 +/- 0.35 and 8.57 +/- 1.08 ms. The increase in long open times with concentration was due primarily to a shift in relative frequency of occurrence of openings from the shortest to the two longest open states. 3. Closed time frequency distributions of closures between main-conductance state openings, closures between sub-conductance state openings and closures between both main- and sub-conductance state openings were fitted with multiple exponential components, suggesting that the channel had several closed states. The two shortest time constants (0.16 +/- 0.01 and 1.26 +/- 0.13 ms) did not vary significantly with concentration (0.5-2 microM) or method of analysis. The longer time constant varied with concentration. 4. Bursts were defined as groups of openings surrounded by closures greater than a critical closed time. For both conductances states, mean burst durations were increased and burst duration frequency histograms were shifted to longer times as glycine concentration was increased from 0.5 to 2 miroM. Burst duration frequency histograms contained four exponential components for the main-conductance state and three exponential components for the sub-conductance state.(ABSTRACT TRUNCATED AT 400 WORDS)
Characterization of eosinophil cell activation by peptides. Differential effects of substance P, melittin, and FMET-Leu-Phe. (1990)

The ability of three different peptides, substance P (SP), FMLP and melittin, to activate eosinophils purified from the peritoneal cavity of human serum-treated guinea pigs was investigated. Degranulation (eosinophil peroxidase, EPO), oxidative burst (O2-), [Ca2+]i mobilization, and arachidonic acid metabolism (thromboxane B2, TXB2) were used as indices of eosinophil activation. SP (100 nM to 100 microM), FMLP (1 to 100 microM) and melittin (10 nM to 100 microM) induced EPO release but only FMLP (1 to 100 microM) led to an elevation of [Ca2+]i. The melittin- and SP-induced EPO secretion occurred at both cytotoxic and noncytotoxic concentrations as assessed by lactate dehydrogenase release. In addition, the effect of SP was not inhibited by the SP analogue (D-Pro4, D-Trp7,9,10)SP(4-11) and SP failed to promote the generation and subsequent release of TXA2. In contrast, FMLP (10 to 100 microM) stimulated the release of TXB2 from guinea pig eosinophils that was selectively inhibited by pretreatment of the cells with BOC-FMLP. On an equimolar basis (1 microM), melittin was approximately fivefold more active at promoting TXB2 release than FMLP. The results indicate that eosinophils respond to the three peptides, SP, melittin, and FMLP in differential fashion. We conclude that activation of guinea pig eosinophils by FMLP is likely to be receptor-mediated whereas the actions of SP and melittin may act through nonspecific peptide-membrane phospholipid interactions.
Localization in sensor networks with fading and mobility (2003)

In sensor networks the device localization is an interesting topic due to its relationship with routing and energy consumption. We propose a scheme to perform localization, based on the estimation of the power received by only two beacons placed in known positions. By starting from the received powers, eventually averaged on a given window to counteract interference and fading, the actual distance between the sensor and the beacons is derived and the position obtained by means of triangulation. The paper shows the effectiveness of this approach in different environments, by including the possible disturbance due to fading channels and sensor mobility.
Metabolite abnormalities in progressive rnultifocal leukoencephalopathy by proton magnetic resonance spectroscopy (1997)

These MRS findings are consistent with neuropathologic observations of neuronal loss, cell membrane and myelin breakdown, and increased glial activity in PML lesions. The CONTRA abnormalities may be due to remote effects of PML or direct HIV-1 infection. 1H MRS may be useful for characterization and follow-up evaluation of PML lesions.
재식밀도 차이가 황금의 수량에 미치는 영향 (2002)

This study was investigated to find out the optimum planting densities of Scutellaria baicalensis George about growth characters, yield components and yield at 3 planting densities by direct sowing cultivated after barley. Stem length was long in dense planting of 20 × 10㎝ and short in spacious planting of 30 × 10㎝ and 40 × 10㎝ by direct sowing cultivated after barley. Stem diameter was thick in spacious planting of 30 × 10㎝ and 40 × 10㎝ and was thin in dense planting of 20 × 10㎝ by direct sowing cultivated after barley. Length and dry weight of root per plant were decreased in dense planting of 20 × 10㎝ and were increased in spacious planting of 30 × 10㎝ and 40 × 10㎝ by direct sowing cultivated after barley. Yield of dry root was highest in optimum planting density(30 × 10㎝:33 plants/㎡) by direct sowing cultivated after barley. The correlation coefficient between number of planting plant and stem length showed highly positive correlation. These characters of stem diameter, number of branches, main root length and yield of dry root mentioned above showed negative correlations with planting plants.
A Spatial Decision Support System Combining GIS and OR Tools to Optimize District Boundaries and Bus Routes for a Suburban School District (2008)

This paper describes a GIS-based spatial decision support system (SDSS) developed to optimize school district boundaries and bus routes in a large suburban school district, Sweet Home Central Schools. This school district is one of the three in the suburb Amherst (population 110,000) of the City of Buffalo, New York State, USA. The school district prompted the study as a result of demographic changes that have affected enrollment distribution among its four elementary schools as well as a recent construction project affecting traffic flow into and out of the school bus depot. In consultation with the school district officials two approaches are developed as part of the SDSS: a clean slate and a community approach. The clean slate approach focuses on minimizing transport costs, while the community approach focuses on the least disruption to the people in the community and balancing socio-economic and diversity issues. Scenarios for both approaches are developed based on current enrollment data.
Studies of early-type variable stars. III. The orbit and physical dimensions for V380 Cygni. (1987)

Nouvelle determination des orbites spectroscopiques des composantes primaires et secondaires de V373 Cas, par des techniques de correlation croisee
Klotho and Phosphate Are Modulators of Pathologic Uremic Cardiac Remodeling (2014)

Cardiac dysfunction in CKD is characterized by aberrant cardiac remodeling with hypertrophy and fibrosis. CKD is a state of severe systemic Klotho deficiency, and restoration of Klotho attenuates vascular calcification associated with CKD. We examined the role of Klotho in cardiac remodeling in models of Klotho deficiency-genetic Klotho hypomorphism, high dietary phosphate intake, aging, and CKD. Klotho-deficient mice exhibited cardiac dysfunction and hypertrophy before 12 weeks of age followed by fibrosis. In wild-type mice, the induction of CKD led to severe cardiovascular changes not observed in control mice. Notably, non-CKD mice fed a high-phosphate diet had lower Klotho levels and greatly accelerated cardiac remodeling associated with normal aging compared with those on a normal diet. Chronic elevation of circulating Klotho because of global overexpression alleviated the cardiac remodeling induced by either high-phosphate diet or CKD. Regardless of the cause of Klotho deficiency, the extent of cardiac hypertrophy and fibrosis correlated tightly with plasma phosphate concentration and inversely with plasma Klotho concentration, even when adjusted for all other covariables. High-fibroblast growth factor-23 concentration positively correlated with cardiac remodeling in a Klotho-deficient state but not a Klotho-replete state. In vitro, Klotho inhibited TGF-β1-, angiotensin II-, or high phosphate-induced fibrosis and abolished TGF-β1- or angiotensin II-induced hypertrophy of cardiomyocytes. In conclusion, Klotho deficiency is a novel intermediate mediator of pathologic cardiac remodeling, and fibroblast growth factor-23 may contribute to cardiac remodeling in concert with Klotho deficiency in CKD, phosphotoxicity, and aging.
Energy Conservation in 802.11 WLAN for Mobile Video Calls (2012)

Battery powered mobile devices suffer from significant power consumption of the WiFi network interface during video calls. By utilizing the dynamic Power Save Mode (PSM), our study proposes an adaptive RTP packet transmission scheme for multimedia traffic. By merging the outbound packet delivery timing with inbound packet reception and estimating each delay component along the packet processing and transmission path, each client manages to meet the stringent end-to-end latency for packets while creating longer sleep intervals. As a benefit it involves no cross-layer communication overhead as the interface state transitions are completely transparent to the application. The experimental results show that 28.53% energy savings on the WiFi interface can be achieved while maintaining satisfactory application performance.
The Current Development of Nanofluid Research (2005)

<div class="htmlview paragraph">It has been shown that the addition of a small amount of nanoparticles into a fluid results in anomalous increase in the thermal conductivity of the mixture, and the resulting nanofluid may provide better overall thermal management and better lubrication in many applications, such as heat transfer fluids, engine oils, transmission fluids, gear oils, coolants and other similar fluids and lubricants. The potential benefits of this technology to the automotive and related industries would be more efficient engines, reduced size and weight of the cooling and propulsion systems, lowered operating temperature of the mechanical systems, and increased life of the engine and other mechanical systems. The new mechanisms for this phenomenon of anomalous thermal conductivity increase have been proposed. The heat transfer properties of a series of graphite nanofluids were presented, and the experimental results were compared with the conventional heat transfer theory for pure liquids. A real-world example of nanofluids, soot-containing diesel engine oils, was presented.</div>
Proliferating cell nuclear antigen expression in childhood acute leukemia (1990)

Proliferating cell nuclear antigen (PCNA) is a 36-Kd nuclear protein, identified as the auxiliary protein of DNA polymerase delta, that is upregulated in activated proliferating cells from a variety of tissues and species, including human lymphocytes. We have examined by two-dimensional polyacrylamide gel electrophoresis the expression of PCNA in various subtypes of childhood acute leukemia and have found differences in its expression according to subtype. These differences were not related to the initial peripheral white blood count, age, or sex, and appeared to reflect differences in proliferative activity between subtypes of acute leukemia.