gebhart/patrepeval huggingface dataset:
Perceptual correlates of massive cortical reorganization (1992)

Following long-term deafferentation of one upper limb in adult primates, the cortical areas corresponding to that limb become responsive to stimuli applied to the face. To explore this phenomenon, we studied some patients after upper limb amputation. In patient VQ, stimuli applied to the lower face or 7 cm above the stump evoked precisely localized referred sensations in individual digits which were often modality specific. Similarly, in another patient, WK several complete somatotopic representations of the phantom limb were found, on the face, chest and axilla, indicating the emergence of such maps in regions remote from the stump. These effects may be a direct perceptual correlate of the physiological observations of Merzenick et al (1984), Wall (1977) and Pons et al (1991).
Conductivity Dependence of PEG Content in an Anhydrous Proton Conducting Sol−Gel Electrolyte (2005)

Proton conducting electrolytes composed of mixtures of a MePEGnSO3H acid and a sol−gel based MePEGn polymer have been prepared. These solutions display anhydrous proton conductivity reaching a maximum value of 1.38 × 10-5 S/cm at 55 °C with a 1.32 M mixture of MePEG16SO3H dissolved in the MePEG12 polymer. The molar equivalent conductivity of the MePEGnSO3H acid is correlated with the volume fraction of PEG present in the mixture. This result indicates that conductivity in these solutions of acid and polymer is a function of the PEG content strongly suggesting the presence of a Grotthus mechanism of conductivity. In addition, we show the lack of a dependence of ionic and equivalent conductivity on the size of the MePEGnSO3H acid, indicating little to no contribution to conductivity from the vehicle mechanism.
Cancer Risk Is Not Increased in Patients Treated for Orthopaedic Diseases with Autologous Bone Marrow Cell Concentrate (2013)

This study found no increased cancer risk in patients after application of autologous cell-based therapy using bone marrow-derived stromal progenitor cells either at the treatment site or elsewhere in the patients after an average follow-up period of 12.5 years.
Triclopyr Safens the Use of Fluazifop and Fenoxaprop on Zoysiagrass While Maintaining Bermudagrass Suppression (2006)

Three sequential applications of fenoxaprop (1.0 lb/acre), fluazifop (0.09 lb/acre), fluroxypyr (0.23 lb/acre), and triclopyr (0.12 lb/acre) applied on 28-day intervals were evaluated alone and in various combinations for bermudagrass suppression in zoysiagrass turf. Triclopyr safened the use of fenoxaprop and fluazifop on zoysiagrass turf without decreasing bermudagrass suppression compared to fenoxaprop or fluazifop alone. The addition of triclopyr improved fenoxaprop suppression of bermudagrass over fenoxaprop alone. While similar in chemistry to triclopyr, fluroxypyr was less phytotoxic to bermudagrass and did not provide beneficial safening of fenoxaprop or fluazifop. Based on this research, triclopyr should be utilized in combination with fluazifop or fenoxaprop to decrease injury from these herbicides and increase bermudagrass suppression when using fenoxaprop.
Substrate dependence of morphology in thin film polymer blends of polystyrene and poly(methyl methacrylate) (2000)

We studied the effects of different substrates on the development of the morphologies in thin film polymer blends in as-spun and annealed films. We have utilized thin films of blends of polystyrene and poly(methyl methacrylate) spun cast on Si, Au and Co surfaces, and produced quantitative composition maps with near edge X-ray absorption fine structure (NEXAFS) microscopy as a function of annealing time. We observed a marked dependence of the morphologies and the qualitative dynamics on the surface composition. © 2000 Society of Chemical Industry
Effectiveness of various therapeutic regimens for bovine brucellosis (1984)

Various chemotherapeutic regimens were evaluated in 48 culture-positive dairy cows. Cessation of shedding of Brucella abortus from udder secretions and absence in selected tissues at necropsy were criteria of success. A combination of a long-acting oxytetracycline and streptomycin eliminated Brucella in 10 of 14 (71.4%) cows. Two cows that were retreated with the same regimen also became culture-negative. Other treatment regimens, including the use of liposome-encapsulated antibiotics, were less successful. Serotests were a poor criterion of effectiveness.
Matching Gas Turbine Propulsion Systems to Vehicles (1968)

<div class="htmlview paragraph">In the past decade a number of experiments by vehicle manufacturers and engine builders have been conducted to evaluate the capabilities of the gas turbine as the powerplant propulsion means.</div> <div class="htmlview paragraph">All too often the choice of the turbine was limited to the availability of the existing models, regardless of the service for which it was designed. To this unit was attached a production transmission manufacturer.</div> <div class="htmlview paragraph">Accessories, such as air cleaners, intake silencers, mufflers, and so on, were components often selected at random from existing stock items remotely related to turbine installations but offered to the automotive trade.</div> <div class="htmlview paragraph">The total result of such a heterogeneous assembly failed to recognize the need for sensitive matching of all components to produce the desired over-all performance of the vehicle and failed to reveal the outstanding advantages of a fully matched gas turbine installation.</div> <div class="htmlview paragraph">This paper reviews some of the presently known and tried gas turbine transmission and component problems and indicated trends toward advanced concepts in over-all matching: <ol class="list nostyle"> <li class="list-item"> <span class="li-label">1.</span> <div class="htmlview paragraph">Significance is given to a review of some of the common installation and matching problems as related to vehicle requirements and their effect on the power packages.</div></li> <li class="list-item"> <span class="li-label">2.</span> <div class="htmlview paragraph">A comparison is made between the turbine and piston engine powerplant related to the trend toward more integrated systems. Comparisons show the gas turbine has inherent advantages and gives good promise for the future.</div></li> <li class="list-item"> <span class="li-label">3.</span> <div class="htmlview paragraph">Some indications are given of what may be expected with the advent of imminent “advanced” turbine systems that give markedly improved performance and have new features.</div></li> <li class="list-item"> <span class="li-label">4.</span> <div class="htmlview paragraph">A brief look is taken at new and more advanced turbine systems.</div></li> <li class="list-item"> <span class="li-label">5.</span> <div class="htmlview paragraph">New possibilities for the turbine powerplant are explored, in an appraisal of its future potentials.</div></li></ol></div>
Colloidal Microgels in Drug Delivery Applications (2006)

Colloidal microgels have recently received attention as environmentally responsive systems and now are increasingly used in applications as carriers for therapeutic drugs and diagnostic agents. Synthetic microgels consist of a crosslinked polymer network that provides a depot for loaded drugs, protection against environmental hazards and template for post-synthetic modification or vectorization of the drug carriers. The aim of this manuscript is to review recent attempts to develop new microgel formulations for oral drug delivery, to design metal-containing microgels for diagnostic and therapeutic applications, and to advance approaches including the systemic administration of microgels. Novel nanogel drug delivery systems developed in the authors' laboratory are discussed in details including aspects of their synthesis, vectorization and recent applications for encapsulation of low molecular weight drugs or formulation of biological macromolecules. The findings reviewed here are encouraging for further development of the nanogels as intelligent drug carriers with such features as targeted delivery and triggered drug release.
Analytic solutions for strain distributions in quantum-wire structures (1997)

Analytic expressions are derived for the strain field due to a lattice-mismatched quantum wire buried in an infinite medium whose cross-section is composed of any combination of line elements and circular arcs. Expressions for the strain field for rectangular, triangular and circular quantum wires are found confirming published results. For the rectangular wire, useful limiting relations are obtained for the stress components close to the edge of the wire. Good agreement is demonstrated with measurements of lattice spacing reported by Chen et al. [Appl. Phys. Lett. 65, 2202 (1994)] for an In0.2Ga0.8As/GaAs rectangular wire if the indium concentration is assumed to be 24%. The strain field of a single AlGaAs/GaAs crescent-shaped wire, with and without lateral wells, is presented. The lateral wells introduce only minor modifications to the strain distribution when compared to a wire of the same thickness but without lateral wells. For a crescent-shaped quantum-wire stack, it is found that the strain field of each wire is almost independent of other wires in the stack when the wire separation is five times the thickness or more.
The potential for using LEO telecommunications constellations to support nanosatellite formation flying (2002)

Abstract This is an investigation to determine if a low‐Earth telecommunications constellation can be used to support data services for small satellites also in Low‐Earth Orbit. The intent is to use the telecommunications service provider satellites to supply low‐rate command and telemetry services as well as inter‐satellite data communications. In this study, we determine access potential via simulations of the orbital contact time using current telecommunications constellation configurations and the assumed configuration for a nanosatellite user. From the access times, we conclude that there are sufficient numbers of contacts to permit command and telemetry services for the nanosatellite constellation. In addition to the access time, we consider Doppler effects, antenna effects, and regulatory restrictions on such communications. However, the regulations do not currently permit such operations on a regular basis. From this analysis, we conclude that the desired communications are possible but the nanosatellite user will need to work closely with the service provider. Copyright © 2002 John Wiley & Sons, Ltd.
Third-Generation Immucillins: Syntheses and Bioactivities of Acyclic Immucillin Inhibitors of Human Purine Nucleoside Phosphorylase (2009)

ImmH (1) and DADMe-ImmH (2) are potent inhibitors of human purine nucleoside phoshorylase (PNP), developed by us and currently in clinical trials for the treatment of a variety of T-cell related diseases. Compounds 1 and 2 were used as templates for the design and synthesis of a series of acyclic immucillin analogues (8-38) in order to identify simplified alternatives to 1 and 2. SerMe-ImmG (8) and DATMe-ImmG (9) displayed the lowest inhibition constants of 2.1 and 3.4 pM, respectively, vs PNP. It was postulated that the flexible natures of 8 and 9 enabled them to adopt conformations resembling those of 1 and 2 within the active site of PNP and that the positioning of two hydroxyl groups was critical for picomolar activity. SerMe-ImmH (10, K(d) = 5.2 pM) was shown to be orally available in mice with a long biological residence time on blood PNP.
CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity (2012)

CD99 is present in many human cell types, including high-level surface expression on pediatric B and T leukemias and Ewing tumors (ETs). On B lymphocytes and respective malignancies, its level decreases with the stage of maturation. Inter-individual variability of CD99 on B-cell precursor acute lymphoblastic leukemia (BCP-ALL) blasts was shown recently to be associated with distinct cytogenetic backgrounds. However, CD99 targets remain mainly unknown. Here, we show that administration of an anti-CD99 antibody to B- and T-leukemia cell lines induces heat shock protein 70 (HSP70), both on the cell surface and in the cytoplasm. Investigation of primary BCP-ALL cells rendered similar results. Intriguingly, CD99-induced modulation of HSP70 on ET cells had profiles different from that on leukemia cells. Since HSP70 expression on tumor cells is a prerequisite for natural killer (NK) cell-mediated tumor lysis, we hypothesized that CD99-induced HSP70 may allow targeting of some CD99-positive malignancies via NK-cell cytotoxicity. Our experiments with NK92 cell line demonstrated that leukemia cells with upregulated HSP70 can be successfully killed by effector cells. We consider our data as a new view of CD99 functions and as a basis for the development of a potential anti-tumor strategy based on heat-shock protein activation via CD99 triggering.
A Set of Versatile Brick Vectors and Promoters for the Assembly, Expression, and Integration of Synthetic Operons in <i>Methylobacterium extorquens</i> AM1 and Other Alphaproteobacteria (2014)

The discipline of synthetic biology requires standardized tools and genetic elements to construct novel functionalities in microorganisms; yet, many model systems still lack such tools. Here, we describe a novel set of vectors that allows the convenient construction of synthetic operons in Methylobacterium extorquens AM1, an important alphaproteobacterial model organism for methylotrophy and a promising platform organism for methanol-based biotechnology. In addition, we provide a set of constitutive alphaproteobacterial promoters of different strengths that were characterized in detail by two approaches: on the single-cell scale and on the cell population level. Finally, we describe a straightforward strategy to deliver synthetic constructs to the genome of M. extorquens AM1 and other Alphaproteobacteria. This study defines a new standard to systematically characterize genetic parts for their use in M. extorquens AM1 by using single-cell fluorescence microscopy and opens the toolbox for synthetic biological applications in M. extorquens AM1 and other alphaproteobacterial model systems.
On-chip sub-terahertz surface plasmon polariton transmission lines with mode converter in CMOS (2016)

An on-chip low-loss and high conversion efficiency plasmonic waveguide converter is demonstrated at sub-THz in CMOS. By introducing a subwavelength periodic corrugated structure onto the transmission line (T-line) implemented by a top-layer metal, surface plasmon polaritons (SPP) are established to propagate signals with strongly localized surface-wave. To match both impedance and momentum of other on-chip components with TEM-wave propagation, a mode converter structure featured by a smooth bridge between the Ground coplanar waveguide (GCPW) with 50 Ω impedance and SPP T-line is proposed. To further reduce area, the converter is ultimately simplified to a gradual increment of groove with smooth gradient. The proposed SPP T-lines with the converter is designed and fabricated in the standard 65 nm CMOS process. Both near-field simulation and measurement results show excellent conversion efficiency from quasi-TEM to SPP modes in a broadband frequency range. The converter achieves wideband impedance matching (<-9 dB) with excellent transmission efficiency (averagely -1.9 dB) from 110 GHz-325 GHz. The demonstrated compact and wideband SPP T-lines with mode converter have shown great potentials to replace existing waveguides as future on-chip THz interconnects. To the best of the author's knowledge, this is the first time to demonstrate the (sub)-THz surface mode conversion on-chip in CMOS technology.
Open commit protocols for the tree of processes model (2002)

The authors propose three different two-phase commit (2PC) protocols that ensure that, even in the presence of permanent node failures, all sane nodes participating in a particular transaction eventually terminate the transaction in a consistent way. A node is defined to be sane if it eventually recovers from failures. These protocols, called open 2PC protocols, are based on a tree-of-processes model and provide means for transferring the coordinator function within process trees. Besides describing the open 2PC protocols in detail, the authors compare these protocols with regard to their message and time complexity. They also include a discussion of related work.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Heat conduction in chain polymer liquids: Molecular dynamics study on the contributions of inter- and intramolecular energy transfer (2011)

In this paper, the molecular mechanisms which determine the thermal conductivity of long chain polymer liquids are discussed, based on the results observed in molecular dynamics simulations. Linear n-alkanes, which are typical polymer molecules, were chosen as the target of our studies. Non-equilibrium molecular dynamics simulations of bulk liquid n-alkanes under a constant temperature gradient were performed. Saturated liquids of n-alkanes with six different chain lengths were examined at the same reduced temperature (0.7T(c)), and the contributions of inter- and intramolecular energy transfer to heat conduction flux, which were identified as components of heat flux by the authors' previous study [J. Chem. Phys. 128, 044504 (2008)], were observed. The present study compared n-alkane liquids with various molecular lengths at the same reduced temperature and corresponding saturated densities, and found that the contribution of intramolecular energy transfer to the total heat flux, relative to that of intermolecular energy transfer, increased with the molecular length. The study revealed that in long chain polymer liquids, thermal energy is mainly transferred in the space along the stiff intramolecular bonds. This finding implies a connection between anisotropic thermal conductivity and the orientation of molecules in various organized structures with long polymer molecules aligned in a certain direction, which includes confined polymer liquids and self-organized structures such as membranes of amphiphilic molecules in water.
Bio-functionalized neurochips (2005)

Arrays of gold microelectrodes have been generated on glass chips. Various adhesion molecules have then been covalently bound to the surface. Micropatterns of adhesion molecules were generated using photolithographic techniques. Dissociated neurons from chicken dorsal root ganglia adhere selectively to the adhesion molecules and form networks. It could be demonstrated that a single neuron can be stimulated by an adjacent microelectrode. The neural outgrowth was much improved on the specific adhesion proteins axonin-1 and NgCAM, compared to surfaces treated with aminosilane. Furthermore, the distance of cell membrane to surface was at a minimum on these specific neural adhesion proteins. These results show that the quality of neuron cultures on chips can be improved if specific neural adhesion proteins are used.
The Assessment of Emotion (2010)

This chapter contains sections titled: Examples of the Mess Emotions, Emotion Regulation and Meta-Emotional Skills Meta-Emotional Skills Measures of Emotion and Emotion Regulation
Distributed Reputation Management for Electronic Commerce (2002)

One of the major challenges for electronic commerce is how to establish a relationship of trust between different parties. Establishing trust is nontrivial, because the traditional physical or social means of trust cannot apply directly in virtual settings. In many cases, the parties involved may not ever have interacted before. Reputation systems seek to address the development of trust by recording the reputations of different parties. However, most existing reputation systems are restricted to individual market websites. Further, relevant information about a party may come from several websites and from interactions that were not mediated by any website. This paper considers the problem of automatically collecting ratings about a given party from others. Our approach involves a distributed agent architecture and adapts the mathematical theory of evidence to represent and propagate the ratings that participants give to each other. When evaluating the trustworthiness of a given party, a peer combines its local evidence (based on direct prior interactions with the party) with the testimonies of others regarding the same party. This approach satisfies certain important properties of distributed reputation management and is experimentally evaluated through simulations.
Isolation of arterial‐specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells (2005)

Arteries are distinguished from veins by differences in gene expression, as well as in their anatomy and physiology. The characterization of arterial- and venous-specific genes may improve our understanding of cardiovascular development and disease. Here we report the results of a subtractive hybridization screen for arterial-specific genes, and describe in detail the expression of a novel arterial-specific gene, Depp (decidual protein induced by progesterone), using a GFP-Cre knock-in that permits a comparison of both instantaneous and cumulative expression patterns in situ. Several features of Depp expression are noteworthy. First, Depp is expressed in endothelial cells of peripheral tissues, but not in atrial or ventricular endocardial cells of the heart. Very few genes have been reported to discriminate between these two cell types, and therefore this specificity may be useful in generating conditional mutations in other genes implicated in cardiovascular development. Second, Depp reveals an unexpected degree of molecular heterogeneity among arterial endothelial cells. Third, Depp is up-regulated in subsets of endothelial cells, in settings of adult neo-vascularization, including tumor angiogenesis. Taken together, these data reveal unanticipated temporal and spatial heterogeneity among arterial endothelial cells of various tissues and organs, raising new questions regarding the functional significance of this diversity.
The Role of Geography of Self in “Filling In” Brand Personality Traits: Consumer Inference of Unobservable Attributes (2013)

While prior research has suggested that brand personality traits can be communicated to consumers via advertising, the question of whether consumers can infer traits that go beyond directly observable traits has not been addressed. Prior research has established that self-generated inferences going beyond direct advertising claims are of significant managerial concern because they can have an even stronger impact on consumers’ brand evaluations than information that is directly communicated. This research investigates whether and how consumers infer unobservable brand traits through advertisements. Specifically, it theorizes that a psychological process—egocentric pattern projection—determines consumers’ inferences about how two brand personality traits are linked on the basis of the extent to which these traits are aligned within the self (i.e., geography of self). Furthermore, the study contributes to the advertising literature by examining and testing the notion that consumers exposed to an advertisement generate expectancies regarding unobservable brand traits that further guide the revision of ambiguous product information on these traits.