gebhart/patrepeval huggingface dataset:
[Treatment of congenital clubfoot with the Ponseti method]. (2002)

Ponseti method proved efficient in correcting idiopathic congenital clubfoot deformities irrespective of initial deformity grades, provided that the details of the technique are strictly adhered to. The results also suggest the role of brace application in order to avoid relapses along with the importance of increasing patients' compliance through family education and experienced orthotists.
Fibrinogen receptors in platelet adhesion to surfaces of extracorporeal circuit (1987)

The role of platelet fibrinogen receptors and platelet-protein interaction in platelet consumption during simulated cardiopulmonary bypass was investigated. In five recirculation experiments, with whole blood, the platelet count fell to 13% of initial values and in two experiments, with blood from patients with Bernard-Soulier syndrome, to 3% of normal values. However, in three experiments with blood from the patients with Glanzmann's thrombasthenia, the platelet count decreased to 69% of initial values. The extent of platelet consumption in normal blood was diminished to only 72% by addition of 0.5 microM prostaglandin E1 (PGE1) (5 experiments) and to 80% by precoating surfaces of the circuit with 2.5% human albumin (5 experiments). beta-Thromboglobulin antigen (beta TG) loss from platelets was associated with thrombocytopenia. The extent of beta TG loss was significantly reduced by the addition of PGE1 to blood or precoating surfaces with albumin. Proteins adsorbed on the surface of the circuit exposed to normal blood were removed with 0.5% Triton X-100. Some of these proteins were identified to be glycoprotein IIIa (GPIIIa) (3.4-4.3 micrograms/ml), beta TG (1.0-1.6 micrograms/ml), and fibrinogen (1.9-3.7 micrograms/ml). The amount of GPIIIa recovered in the Triton X-100 eluates correlated with the number of platelets lost during recirculation. These studies indicate that exposure of fibrinogen receptors associated with GPIIb-GPIIIa complex contributes to platelet consumption during cardiopulmonary bypass.
3,4-Dichlorotetramethylene Sulfone (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT3,4-Dichlorotetramethylene SulfoneT. Earl. Jordan and Frank. KipnisCite this: J. Am. Chem. Soc. 1949, 71, 5, 1875–1876Publication Date (Print):May 1, 1949Publication History Published online1 May 2002Published inissue 1 May 1949https://pubs.acs.org/doi/10.1021/ja01173a516https://doi.org/10.1021/ja01173a516research-articleACS PublicationsRequest reuse permissionsArticle Views31Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Reactive Vega: A Streaming Dataflow Architecture for Declarative Interactive Visualization (2015)

We present Reactive Vega, a system architecture that provides the first robust and comprehensive treatment of declarative visual and interaction design for data visualization. Starting from a single declarative specification, Reactive Vega constructs a dataflow graph in which input data, scene graph elements, and interaction events are all treated as first-class streaming data sources. To support expressive interactive visualizations that may involve time-varying scalar, relational, or hierarchical data, Reactive Vega's dataflow graph can dynamically re-write itself at runtime by extending or pruning branches in a data-driven fashion. We discuss both compile- and run-time optimizations applied within Reactive Vega, and share the results of benchmark studies that indicate superior interactive performance to both D3 and the original, non-reactive Vega system.
RGB-D Visual Search with Compact Binary Codes (2015)

As integration of depth sensing into mobile devices is likely forthcoming, we investigate on merging appearance and shape information for mobile visual search. Accordingly, we propose an RGB-D search engine architecture that can attain high recognition rates with peculiarly moderate bandwidth requirements. Our experiments include a comparison to the CDVS (Compact Descriptors for Visual Search) pipeline, candidate to become part of the MPEG-7 standard, and contribute to elucidate on the merits and limitations of joint deployment of depth and color in mobile visual search.
Type 5 Phosphodiesterase Inhibitors in the Treatment of Erectile Dysfunction and Cardiovascular Disease (2007)

Since the discovery of sildenafil in 1989 as a highly selective inhibitor of the phosphodiesterase type-5 (PDE-5) receptor, 2 additional PDE-5 inhibitors, tadalafil and vardenafil, have emerged as safe and effective treatments of erectile dysfunction (ED). Enzymes in the PDE family catalyze the hydrolysis of the intracellular signaling molecules cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), which is the second messenger of nitric oxide (NO) and a principal mediator of smooth muscle relaxation and vasodilation. Sildenafil was initially introduced for clinical use as the result of extensive research on chemical agents targeting PDE-5 that might potentially be useful in the treatment of coronary heart disease. Erection is largely a hemodynamic event, which is regulated by vascular tone and blood flow balance in the penis. Endothelial dysfunction, an early component of atherosclerosis, may inhibit a vascular event such as erection and is rarely confined to the arteries supplying blood to the penis, but more likely occurs throughout the vascular bed. In addition to the effects of the NO-cGMP signaling pathway on cavernosal smooth muscle, clinical findings have suggested that vascular tone in the pulmonary, coronary, and other vascular tissues expressed by PDE-5 is also influenced by this signal transduction mechanism. This has led to the emergence of novel therapeutic indications for sildenafil over a range of cardiovascular conditions that are either well-established risk factors or comorbidities with ED. Recently, the U.S. Food and Drug Administration approved sildenafil as an orally active therapy for the treatment of primary pulmonary hypertension. The drug will be marketed under the trade name of Revatio, not Viagra, the name used for the ED indication. The approved dose for primary pulmonary hypertension is 20 mg 3 times daily.
Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro (2013)

A large percentage of the population may be expected to experience painful symptoms or disability associated with intervertebral disc (IVD) degeneration - a condition characterized by diminished integrity of tissue components. Great interest exists in the use of autologous or allogeneic cells delivered to the degenerated IVD to promote matrix regeneration. Induced pluripotent stem cells (iPSCs), derived from a patient's own somatic cells, have demonstrated their capacity to differentiate into various cell types although their potential to differentiate into an IVD cell has not yet been demonstrated. The overall objective of this study was to assess the possibility of generating iPSC-derived nucleus pulposus (NP) cells in a mouse model, a cell population that is entirely derived from notochord. This study employed magnetic activated cell sorting (MACS) to isolate a CD24(+) iPSC subpopulation. Notochordal cell-related gene expression was analyzed in this CD24(+) cell fraction via real time RT-PCR. CD24(+) iPSCs were then cultured in a laminin-rich culture system for up to 28 days, and the mouse NP phenotype was assessed by immunostaining. This study also focused on producing a more conducive environment for NP differentiation of mouse iPSCs with addition of low oxygen tension and notochordal cell conditioned medium (NCCM) to the culture platform. iPSCs were evaluated for an ability to adopt an NP-like phenotype through a combination of immunostaining and biochemical assays. Results demonstrated that a CD24(+) fraction of mouse iPSCs could be retrieved and differentiated into a population that could synthesize matrix components similar to that in native NP. Likewise, the addition of a hypoxic environment and NCCM induced a similar phenotypic result. In conclusion, this study suggests that mouse iPSCs have the potential to differentiate into NP-like cells and suggests the possibility that they may be used as a novel cell source for cellular therapy in the IVD.
A study on likely impact of FDI on Indian retailing sector (2011)

Retailing sector in India has undergone significant transformation in the past 10 years. This sector witnessed significant developments from small unorganized family-owned retail formats to organised retailing. In spite of the recent developments in retailing & its immense contribution to the economy, retailing continues to be one of the least evolved industries and the growth of organised retailing in India has been much slower as compared to rest of the world. Multi branding retailing is one of the sectors where Foreign Direct Investment is not allowed. There is an intense discussion on pros and cons of opening up this sector to FDI. There have been protests by trading associations and other stake holders against allowing FDI in retiling; however with high GDP growth, increased consumerism and liberalization, India is being portrayed as an attractive destination for foreign direct investment (FDI) in retailing. The objective of this study is to evaluate the likely impact of FDI across different retail segments. The study also looks at the challenges and possible threats to unorganized and organized domestic retailers from entry of foreign players. Impact of the entry of foreign players on employment, prices, sourcing, technology and efficiency etc are also discussed. This study would help to prospective researchers to know various entry routes of foreign players, likely impact of FDI on retail sector.
Multipath Transmission with Forward Error Correction Mechanism for Delay-Sensitive Video Communications (2010)

The Concurrent Multipath Transmit with Forward Error Correction (CMT-FEC) mechanism uses multiple paths for data transfer and employs Forward Error Correction (FEC) to adapt to changing conditions in the wireless network. The CMT-FEC mechanism cannot be used in delay-sensitive video communications when the FEC block length is longer than the end-to-end delay because this will lead to the video frame not being playable on-time at the receiver end. This paper proposes the Delay-sensitive Multipath FEC (DM-FEC) mechanism using a mathematical analytical model to determine the appropriate transmission rate, FEC block length, and FEC redundancy on each path in a multipath environment. The DM-FEC mechanism does not cause the video frame to be unplayable or impede the timely recovery of video information.
Tow Noise Suppression in Marine Hydrostreamers (1995)

As advances in electronics give ever-increasing precision in the acquisition of digital data, matching improvements are needed in the quality of the primary sensors. In an active system, it is always possible to increase the level of the sound source but real improvements in data quality can be also be achieved by reducing the sources of acoustic noise.
ChemInform Abstract: Properties of Chemical Vapor Deposited Tungsten Silicide Films Using Reaction of WF6 and Si2H6. (1987)

Abstract It is shown that CVD tungsten silicide films prepared by reaction of WF 6 and Si 2 H 6 have a higher deposition rate and higher Si content than those obtained from WF 6 and SiH 4 at the same substrate temperature.
MMPS: A Versatile Mobile-to-Mobile Payment System (2005)

The paper presents an effective mobile-to-mobile payment system. A mobile phone with or without SIM card is enabled as an EMV payment instrument and is linked to a debit or credit account in a bank to pay merchant who has a mobile phone or an online EMV capable terminal. In a single phone, multiple credit or debit accounts from different banks can be configured without compromising on security. The proposed framework provides a secure and convenient payment mechanism without any terminal infrastructure.
Josephson vortex in a ratchet potential:  Theory (2001)

We propose a type of Josephson vortex ratchet. In this system a Josephson vortex moves in a periodic asymmetric potential under the action of a deterministic or random force with zero time average. For some implementations the amplitude of the potential can be controlled during the experiment, thus allowing us to tune the performance of the system and build rocking as well as flashing ratchets. We discuss the differences between conventional and Josephson vortex ratchets and present a model describing the dynamics of the fluxon in such a system. We show numerical simulation results that predict rectification of a monochromatic, deterministic signal with zero time average. The investigation of this system may lead to the development of the fluxon rectifier-a device that produces a dc voltage from nonequilibrium fluctuations.
Synthesis and Rearrangement of Aminoalkyl Lactones to Spirocyclic Hydroxymethyl Lactams (1992)

Lithiation of lactones (1) and (2) followed by electrophilic substitution with dibromoalkanes afforded bromoalkyl lactones (3a-3c) and (4a-4c). Treatment of 3a, 3b, 4a and 4b with primary amines led to formation of aminoalkyl lactones (5a, 5b, 6a, 6b and 11), which were rearranged to spirocyclic hydroxyalkyl lactams (7a, 7b, 8a, 8b and 12). Spirocyclic lactams (7a, 7b, 8a and 8b) were reduced to spirocyclic amines (9a, 9b, 10a, and 10b), whereas reduction of lactam (12) gave a separable mixture of amine (13) and tricyclic aminal (15)
Sub-100 nm features seamless roller mold using anodization and atomic layer deposition, for roll-to-roll nanoimprint lithography (2016)

The authors demonstrate an approach using direct anodization and atomic layer deposition (ALD) to prepare a sub-100 nm seamless roller mold for roll-to-roll nanoimprinting. In this approach, the roller mold is prepared by direct anodization of a cylindrical Al roller and the mold's pore size is further reduced by ALD process. This direct anodization of the Al rod as a roller mold creates a hard and durable seamless roller mold for nanoimprinting process. The pores were found to be uniformly anodized on the cylindrical Al rod and ordered pores can be obtained after multisteps anodization. The sub-100 nm pores are hexagonally packed with a diameter of 43.8 ± 3 nm (before pore-widening process) and interpore spacing of 87.0 ± 8 nm, estimated using an image processing software (imagej). The size, interpore spacing, and depth of the pores depend on the anodization conditions such as type of electrolyte solution, anodization voltage, and duration. The pores' size can be further reduced by ALD of TiO2 film which can coat conformally and precisely onto the cylindrical Al roller mold. The Al roller mold was nanoimprinted onto polycarbonate (PC) and creates PC nanopillars of desired dimensions depending on the anodization condition and the number of ALD cycles. Thus, sub-100 nm pattern resolution can be produced directly on a cylindrical object, achieving a high resolution and seamless roller mold for continuous nanoimprint processing.
Los comentarios supradialogales en una farsa profana: la Farsa de la ventera (2001)

La Farsa de la Ventera, a pesar de tratar un asunto profano, contiene un propósito aleccionador múltiple que la acerca en parte a los objetivos de las farsas de tema religioso. Nos podemos preguntar sin embargo si su naturaleza profana incide en las técnicas de la interlocución. La farsa consta de 320 versos y se la puede clasificar entre las obras de extensión media. En ella actúan seis personajes, lo cual representa un número bastante elevado de protagonistas. El orden con el cual se mencio...
Active specific immunotherapy of metastatic melanoma with an antiidiotype vaccine: a phase I/II trial of I-Mel-2 plus SAF-m. (1997)

I-Mel-2 antiidiotype vaccine was safe, tolerated best at the 100-microgram dose of SAF-m, and had immunologic and clinical activity.
Pubovaginal slings: a review of the technical variables (2001)

The pubovaginal sling, reintroduced in the late 1970s by Maguire and Blaivas, has become the gold standard for managing anatomic incontinence. Newer technology, materials, surgical techniques and even new theories on the mechanism of action are evolving to further reduce the morbidity of these procedures and improve patient satisfaction. In the following review, we will highlight some of the exciting advances we have witnessed over the last year and try to put them into perspective for the reader.
Faults and Folds Across Cordilleran Trends at the Headwaters of Leduc River, Northern British Columbia (2015)

The 24 papers in this volume, written in honor of A.F. Buddington, cover a wide range of topics and geographic areas. H.H. Hesss History of Ocean Basins perhaps the most famous paper in the volume, introduces the concept of seafloor spreading.
Resonance Raman and magnetic circular dichroism studies of reduced [2Fe-2S] proteins. (1992)

The structural and electronic properties of the [2Fe-2S] clusters in reduced putidaredoxin, Spinacea oleracea ferredoxin, and Clostridium pasteurianum [2Fe-2S] ferredoxin have been investigated by resonance Raman and variable temperature magnetic circular dichroism spectroscopies. Both techniques are shown to provide diagnostic fingerprints for identifying [2Fe-2S]+ clusters in more complex multicomponent metalloenzymes. The Fe-S stretching modes of oxidized and reduced putidaredoxin are assigned via 34S and D2O isotope shifts and previous normal mode calculations for adrenodoxin (Han, S., Czernuszewicz, R. S., Kimura, T., Adams, M. W. W., and Spiro, T. G. (1989) J. Am. Chem. Soc. 111, 3505-3511). The close similarity in the resonance Raman spectra of reduced [2Fe-2S] centers, in terms of both the vibrational frequencies and enhancement profiles of the Fe-S stretching modes, permits these assignments to be generalized to all clusters of this type. Modes primarily involving Fe(III)-S(Cys) stretching are identified in all three reduced [2Fe-2S] proteins, and the frequencies are rationalized in terms of the conformation of the cysteine residues ligating the Fe(III) site of the localized valence reduced cluster. D2O isotope shifts indicate few, if any, amide NH-S hydrogen bond interactions involving the cysteines ligating the Fe(III) site. Preliminary resonance Raman excitation profiles suggest assignments for the complex pattern of electronic bands that comprise the low temperature magnetic circular dichroism spectra of the reduced proteins. S----Fe(III) and Fe(II)----S charge transfer, Fe d-d, and Fe(II)----Fe(III) intervalence bands are identified.
ANAEROBIC GROWTH OF <i>FUSARIUM OXYSPORUM</i> (1964)

Gunner, H. B. (Cornell University, Ithaca, N.Y.), and M. Alexander. Anaerobic growth of Fusarium oxysporum. J. Bacteriol. 87:1309-1316. 1964.-Fusarium oxysporum, an alleged obligate aerobe, was found to be capable of growth in the absence of molecular oxygen, provided the medium contained yeast extract, MnO(2), nitrate, selenite, or ferric ions. The active substance in yeast extract was not identified. The fungus possessed hydrogenase, and was capable of utilizing H(2). Under anaerobic conditions, the fungus effected the reduction of nitrate, ceric, ferric, selenite, and tellurite ions, as well as the reduction of several inorganic sulfur compounds and indicators having positive oxidation-reduction potentials. The products of anaerobic nitrate-dependent growth were ethanol, CO(2), acetic acid, and ammonia. Possible explanations for the apparent inability of obligate aerobes to grow in the absence of O(2) are discussed.
Ionic doping effect in ZrO2 resistive switching memory (2010)

Oxygen vacancy (VO) plays the critical role for resistive switching in transition metal oxide resistive random access memory (RRAM). First principles calculation is performed to study the impact of metallic ion (Al, Ti, or La) doping in ZrO2 on the behaviors of VO, including defect energy level and formation energy (Evf). Trivalent dopant (Al or La) significantly reduces Evf. Based on the calculated results, ZrO2-based RRAM devices are designed to control the formation of VO, and improved resistive switching uniformity is demonstrated in experiments.
[Study of biologically active currents of the external ear in endaural pharmacophysical intervention]. (1989)

This study demonstrated that biologically active points (BAP) of external ear were sensitive to ultrasonic treatment. In order to identify their characteristics, specific conductivity of tissues in the BAP area was measured (in microamperes) by an Elita 4-PEP unit equipped with a silver probe. Conductivity was measured in five points. Such points as i-feng, er-meng, nei-er were shown to influence the cochleovestibular system and exhibit conductivity of approximately 150 microA. The risk of point hyperactivity increased drastically by the 4th and 13th exposure in response to unilateral endaural pharmacophysical treatment with 0.4 W/cm2 ultrasound. The use of ultrasound of lower intensity (0.05-0.2 W/cm2) helped to avoid this complication. These observations suggest that phonopuncture can constitute a component of endaural pharmacophysical treatment of internal ear.
The Preparation of Trehalose from Yeast<sup>1</sup> (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation of Trehalose from Yeast1Laura C. Stewart, Nelson K. Richtmyer, and C. S. HudsonCite this: J. Am. Chem. Soc. 1950, 72, 5, 2059–2061Publication Date (Print):May 1, 1950Publication History Published online1 May 2002Published inissue 1 May 1950https://doi.org/10.1021/ja01161a050RIGHTS & PERMISSIONSArticle Views185Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (397 KB) Get e-Alerts Get e-Alerts