gebhart/patrepeval huggingface dataset:
Nonstop Update of Running Robot Controller Programs (2004)

This paper presents a method to update running RTLinux robot controller programs (RTU) on the fly. The proposed method exploits thread swapping. This paper focuses on the safety conditions of thread swapping, platform requirements, realtime issues, and uncertainties in RTU completion time. This paper introduces RTU-able software design by layered modules which enable the update of servo functions and robot model global variables. We have developed a RTU-able mobile manipulator controller, evaluated its performance by worst case results, and shown its practical applicability.
Human immunodeficiency virus and hepatitis C virus co-infection. (2006)

Hepatitis C virus (HCV) infection is a major cause of liver disease and hepatocellular carcinoma worldwide, as well as the leading cause of liver transplantations in the United States. As a result of similar modes of transmission, approximately 30% of HIV-infected individuals are co-infected with HCV. Among intravenous drug users, almost 90% of people infected with HIV are also infected with HCV. Because of treatment with highly active anti-retroviral therapy, HIV-infected individuals have improved survival and are no longer suffering from opportunistic infections and malignancy as in years past. As a result, co-infection with HCV has now become a frequent cause of morbidity and mortality in HIV-infected individuals. Furthermore, liver disease secondary to HCV infection is now the leading cause of hospital deaths in HIV-infected people in the US. HIV infection accelerates the course of HCV-related liver disease and viremia. It is less clear whether HCV infection affects the clinical course of HIV; however, HCV-related liver disease can limit many individuals from receiving anti-HIV therapy. HIV/ HCV co-infection is common, and serious. Physicians caring for HIV-infected patients worldwide must now address hepatitis C virus co-infection.
Toward Efficient Content Delivery for Automated Driving Services: An Edge Computing Solution (2018)

Automated driving is coming with enormous potential for safer, more convenient, and more efficient transportation systems. Besides onboard sensing, autonomous vehicles can also access various cloud services such as high definition maps and dynamic path planning through cellular networks to precisely understand the real-time driving environments. However, these automated driving services, which have large content volume, are time-varying, location-dependent, and delay-constrained. Therefore, cellular networks will face the challenge of meeting this extreme performance demand. To cope with the challenge, by leveraging the emerging mobile edge computing technique, in this article, we first propose a two-level edge computing architecture for automated driving services in order to make full use of the intelligence at the wireless edge (i.e., base stations and autonomous vehicles) for coordinated content delivery. We then investigate the research challenges of wireless edge caching and vehicular content sharing. Finally, we propose potential solutions to these challenges and evaluate them using real and synthetic traces. Simulation results demonstrate that the proposed solutions can significantly reduce the backhaul and wireless bottlenecks of cellular networks while ensuring the quality of automated driving services.
Molecular structure of fluoxetine hydrochloride, a highly selective serotonin-uptake inhibitor (1988)

Fluoxetine, a selective inhibitor of serotonin uptake, is clinically useful in treating depression and may be useful for management of a variety of other psychiatric and metabolic derangements. Using X-ray crystallography, we have determined the three-dimensional structure of fluoxetine hydrochloride. A total of 2394 unique reflections were measured, and full-matrix least-squares refinement of all non-hydrogen coordinates and thermal parameters gave a final discrepancy index of 0.074 for 1759 observed reflections. In the solid state, the planes defined by the two aromatic rings are skewed, precluding the possibility of intramolecular ring-ring interactions. The methylene units of the methylpropanamine moiety adopt the anticipated conformational relationships to minimize torsional strain. An exact antiperiplanar relationship exists between N11 and C3; the N11-C1-C2-C3 dihedral angle is -180 degrees. The C1-C2-C3-O4 dihedral angle is 60.6 degrees, indicating that the propanamine side-chain folds toward the phenoxy moiety rather than adopting a fully extended conformation. This folded three-dimensional relationship may be necessary for high-affinity interaction with the serotonin-uptake carrier and confers considerable structural homology between this portion of fluoxetine and the phenylcyclohexylamine substructure of sertraline and EXP-561. However, the nature of substituents on the phenoxy portion of fluoxetine is also critical in determining potency and selectivity in this series of compounds.
Epitaxial titanium diboride films grown by pulsed-laser deposition (2002)

Epitaxial, smooth, and low-resistivity titanium diboride (TiB2) films have been grown on SiC substrates using pulsed-laser deposition. Combined studies from ex situ x-ray diffraction and in situ reflection high-energy electron diffraction indicate the crystallographic alignment between TiB2 and SiC both parallel and normal to the substrate. Atomic force microscopy and scanning electron microscopy studies show that these epitaxial films have a smooth surface, and the resistivity of these films is comparable to that of single-crystal TiB2. Growth of these films is motivated by this material’s structural and chemical similarity and lattice match to the newly discovered superconductor MgB2, both to gain further insight into the physical mechanisms of diborides in general and, more specifically, as a component of MgB2-based thin-film heterostructures.
Atomic magnetometry with maximally polarized states (2009)

A new magnetometry method based on electromagnetic induced transparency (EIT) with maximally polarized states is demonstrated. An EIT hyperfine resonance, comprising the m(F)=F state (end-state), is observed at a non-zero angle between the laser beam and the magnetic field. The method takes advantage of the process of end-state pumping, a well-known rival of simpler EIT magnetometry schemes, and therefore benefits at a high laser power. An experimental demonstration and a numerical analysis of the magnetometry method are presented. The analysis points on a clear sensitivity advantage of the end-state EIT magnetometer.
Purification and Characterization of New Special Ginsenosidase Hydrolyzing Multi-Glycisides of Protopanaxadiol Ginsenosides, Ginsenosidase Type I (2007)

In this paper, the new type ginsenosidase which hydrolyzing multi-glycosides of ginsenoside, named ginsenoside type I from Aspergillus sp.g48p strain was isolated, characterized and generally described. The enzyme molecular weight was about 80 kDa. Ginsenosidase type I can hydrolyze different glycoside of protopanaxadiol type ginsenosides (PPD); i.e., can hydrolyze the 3(carbon)-O-beta-glucoside of Rb1, Rb2, Rb3, Rc, Rd; can hydrolyze 20(carbon)-O-beta-glucoside of Rb1, 20-O-beta-xyloside of Rb3, 20-O-alpha-arabinoside(p) of Rb2 and 20-O-alpha-arabinoside(f) of Rc to produce mainly F2, compound-K (C-K) and small Rh2, but can not hydrolyze the glycosides of protopanaxatriol type ginsenoside (PPT) such as Re, Rf, Rg1. So, when the ginsenosidase type I hydrolyzed ginsenosides, the enzyme selected ginsenoside-aglycone type, can hydrolyze different glycosides of PPD type ginsenoside; however no selected glycoside type, can hydrolyze multi-glycosides of PPD type ginsenosides. These properties were novel properties, and differentiated with the other previously described glycosidases.
Improving data quality: consistency and accuracy (2007)

Two central criteria for data quality are consistency and accuracy. Inconsistencies and errors in a database often emerge as violations of integrity constraints. Given a dirty database D, one needs automated methods to make it consistent, i.e., find a repair D ′ that satisfies the constraints and “minimally ” differs from D. Equally important is to ensure that the automatically-generated repair D ′ is accurate, or makes sense, i.e., D ′ differs from the “correct ” data within a predefined bound. This paper studies effective methods for improving both data consistency and accuracy. We employ a class of conditional functional dependencies (CFDs) proposed in [6] to specify the consistency of the data, which are able to capture inconsistencies and errors beyond what their traditional counterparts can catch. To improve the consistency of the data, we propose two algorithms: one for automatically computing a repair D ′ that satisfies a given set of CFDs, and the other for incrementally finding a repair in response to updates to a clean database. We show that both problems are intractable. Although our algorithms are necessarily heuristic, we experimentally verify that the methods are effective and efficient. Moreover, we develop a statistical method that guarantees that the repairs found by the algorithms are accurate above a predefined rate without incurring excessive user interaction. 1.
Characterization, Purification, and SubceUuIar Localization of Bovine Thyroid Sialidases1 (1984)

Sialidase activities have been studied in bovine thyroid using sialoglycolipids, sialoglycoproteins, sialo-oligosaccharides and fluorogenic 4-methylumbelliferyl-alpha-D-N-acetylneuraminate as substrates. No sialidase activity could be detected towards native glycoprotein substrates. From enzyme kinetics, effector data and more convincingly from subcellular studies it became clear that in bovine thyroid at least two sialidase activities were present, a sialyllactitol sialidase confined to the lysosomal membrane and a glycolipid sialidase residing in the plasma membrane and displaying the features of a true ectoenzyme. The lipid requirement for full enzyme activity supported the membrane bound character of both sialidase activities. A soluble sialidase activity could not be demonstrated. After solubilization by CHAPS treatment, partial purification of the sialyllactitol sialidase could be achieved by affinity chromatography (Sepharose diamino dipropylamino-N-acetylneuraminic acid). The purified enzyme was extremely labile. Titration of the sialidase preparation with amino acid modifying agents revealed that sulfhydryl- and tryptophanyl groups were essential for the sialidase action.
<title>New avalanche device with the ability of analog few-photon pulse detection</title> (1995)

The task of analog few-photon pulse detection and measurement can be solved if two main conditions are carried out: the high quantum efficiency is realized and low noise mechanism of the internal amplification is used. Traditional facilities do not allow to perform both of these conditions in one device. So vacuum photomultiplier has high gain and low noise but its quantum efficiency is not rather high. Another wide spread device-avalanche photodiode having sufficiently high quantum efficiency displays very rapid rise of noise factor with gain increasing. In this report the ability of analog few-photon detection (AFPD) mode realizing by the new type of photodetectors--avalanche with negitive feedback (ANF) photodiodes is appreciated. As known single carrier avalanche process with negative feedback (SC ANF), when negative feedback governs the avalanche process initiated by one separate charge carrier, have the main features similar to those of 'ideal' amplifier: high gain, low noise, and fastness. Considering that the SC ANF photodetector as semi-conductor device has also high quantum efficiency it may be the adequate facility for AFPD in principle. In the report the properties of SC ANF process determined the characteristics and parameters of high sensitive analog photodetector such as gain, amplification fluctuations and efficiency, rise time are demonstrated and discussed. The analog detection of a several-photoelectron pulse is illustrated.
Nucleotide sequence and gene organization of the gerK spore germination locus of Bacillus subtilis 168. (1996)

The nucleotide sequence of the whole gerK spore germination locus of Bacillus subtilis has been determined by sequencing the remaining first and third genes of the locus. The gerK locus contained three open reading frames capable of encoding polypeptides of 546, 407 and 373 amino acids. Each predicted gene product had homologues in the gerA and gerB operon, but the gene order was different from that of gerA and gerB. Sequences regarded as -10 and -35 promoter sequences for the sigma-G type RNA polymerase was found upstream of the first gene suggesting that the gerK also is an operon expressed specifically in the forespore during sporulation. All three genes were suggested to be essential for spore germination in response to glucose.
Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons (1993)

Basic fibroblast growth factor (bFGF) was recently found to modulate the outgrowth-regulating effects of glutamate, and protected neurons from several brain regions against excitotoxi/ischemic damage. We provide evidence that the excitoprotective mechanism of bFGF involves suppression of the expression of a 71 kDa NMDA receptor protein (NMDARP-71). NMDARP-71 protein and mRNA levels were reduced in neurons in bFGF-treated hippocampal cell cultures. The levels of the NMDARP-71 were not reduced by NGF or epidermal growth factor, and bFGF did not reduce the level of mRNA for the GluR1 kainate/AMPA receptor, demonstrating the specificity of the effect of bFGF on the NMDARP-71. The reduction in NMDARP-71 expression in bFGF-treated neurons was correlated with reduced vulnerability to NMDA neurotoxicity. A major role for NMDARP-71 in calcium responses to NMDA and excitotoxicity was demonstrated using antisense oligonucleotides directed against NMDARP-71. Northern and Western blot analysis and immunocytochemistry showed that NMDARP-71 antisense oligonucleotides caused a selective suppression of NMDARP-71 mRNA and protein levels during 12-44 hr exposure periods. Elevations in intracellular calcium levels normally caused by glutamate and NMDA were attenuated in neurons exposed to NMDARP-71 antisense oligonucleotide; calcium responses to kainate were relatively unaffected. NMDARP-71 antisense oligonucleotides protected the neurons against excitotoxicity. Thus, NMDARP-71 is a necessary component of an NMDA receptor mediating calcium responses and neurotoxicity in hippocampal neurons. Taken together, these data identify a mechanism whereby bFGF can modify neuronal responses to glutamate, and suggest that regulating the expression of excitatory amino acid receptors may provide a means for growth factors to influence the plasticity and degeneration of neural circuits.
Nature of the Co-Mn-Br Catalyst in the Methylaromatic Compounds Process (1993)

We have used the reaction of m-chloroperbenzoic acid with Co/Mn/Br as a model system to attempt to understand the nature of this important autoxidation catalyst. Using stopped-flow and UV-VIS kinetic techniques, we have determined the step-wise order in which the catalyst components react with each other. The cobalt(II) is initially oxidized to Co(III) by the peracid, the cobalt(III) then oxidizes the manganese to Mn(III), which then oxidizes the bromide. The order of these redox reactions is the opposite to that expected from thermodynamics. Suggestions will be made of the relationship of this model to the known characteristics of autoxidation processes.
Hilgers, Die katholische Lehre von den Ablässen und deren geschichtliche Entwicklung. Mit Anlagen und drei Abbildungen (1915)

Article Hilgers, Die katholische Lehre von den Ablässen und deren geschichtliche Entwicklung. Mit Anlagen und drei Abbildungen was published on August 1, 1915 in the journal Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Kanonistische Abteilung (volume 5, issue 1).
POLYMERIZATION OF METHYL METHACRYLATE INITIATED WITH POLY(FORMYLSTYRENE) (1979)

Abstract The polymerization of methyl methacrylate(MMA) initiated by poly(formylstyrene) (PFS) was carried out in p-dioxane at 85°C. The rate of polymerization was expressed by the following equation: Rp = const. [PFS]0.43[MMA]1.31. The polymerization proceeded homogeneously through a radical mechanism. The initiating ability of PFS was found to be larger than that of benzaldehyde indicating a macromolecular effect on the polymerization.
Extrapituitary Prolactin: Distribution, Regulation, Functions, and Clinical Aspects* (1996)

PRL affects more physiological processes than all other pituitary hormones combined. Among these are the regulation of mammary gland development, initiation and maintenance of lactation, immune modulation, osmoregulation, and behavioral modification. At the cellular level, PRL exerts mitogenic, morphogenic, or secretory activities. This raises the question as to the mechanism by which a single hormone can modulate so many seemingly unrelated functions. This review addresses the concept of the dual function of PRL, as a circulating hormone and a cytokine. The diversity of PRL actions is derived from three components: structural polymorphism, local production and processing, and divergent intracellular signaling pathways and target genes. PRL can be easily classified as a cytokine based on its shared properties with hematopoietic growth factors. These include comparable structural motifs, multiple sites of synthesis, ubiquitous receptor distribution, homologous receptor structure, and similar signal transduction pathways. A seminal report by Nagy and Berczi (1) drew attention to extrapituitary PRL. They reported that hypophysectomized female rats had 10–20% lactogenic activity in their serum as compared with controls. Within 2 months, the lactogenic activity gradually increased to 50% of controls.
Oxygen atom transfer among rhenium, sulfur, and phosphorus. Characterization and reactivity of Re(O)Cl3(Me2S)(OPPh3) and Re(O)Cl3(CNCMe3)2 (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxygen atom transfer among rhenium, sulfur, and phosphorus. Characterization and reactivity of Re(O)Cl3(Me2S)(OPPh3) and Re(O)Cl3(CNCMe3)2Jeffrey C. Bryan, Ronald E. Stenkamp, T. H. Tulip, and James M. MayerCite this: Inorg. Chem. 1987, 26, 14, 2283–2288Publication Date (Print):July 15, 1987Publication History Published online1 May 2002Published inissue 15 July 1987https://doi.org/10.1021/ic00261a024Request reuse permissionsArticle Views466Altmetric-Citations83LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (798 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Privacy-Preserving Data Management in Mobile Environments: A Partial Encryption Approach (2012)

With the growing demand for data-sensitive applications employing mobile devices, such as mobile clinics in remote villages and remote sensors collecting sensitive data, there is a need for a new architectural paradigm for mobile data management. Typically, these mobile devices have limited storage and processing capabilities, and operate in unreliable environments leading to possible loss of valuable data, if not properly managed. Often, the collected data is periodically offloaded to a remote server such as a cloud. However, such offloading may lead to violation of privacy if the network/server cannot be fully trusted. While encrypting the data prior to offloading appears to be a solution for this problem, this is computationally intensive and infeasible when mobile devices are employed. In this paper, we propose a partial-encryption scheme that takes into account both the privacy (confidentiality) constraints of the data being collected and the limitations of the mobile devices. The scheme employs vertical and horizontal fragmentation to determine those parts that need to be encrypted and those that can be sent in clear. The privacy constraints are represented in terms of a constraint graph and two-coloring problem solution is applied to identify the portions of the data that need to be encrypted. Any cycles in the constraint graph are handled using heuristics. The approach is effective in integrating unsecured wireless/internet with the untrusted yet cheap cloud storage servers, using the capacity-constrained mobile devices to manage sensitive data.
There goes the neighborhood (2013)

Predictable performance is important for understanding and alleviating application performance issues; quantifying the effects of source code, compiler, or system software changes; estimating the time required for batch jobs; and determining the allocation requests for proposals. Our experiments show that on a Cray XE system, the execution time of a communication-heavy parallel application ranges from 28% faster to 41% slower than the average observed performance. Blue Gene systems, on the other hand, demonstrate no noticeable run-to-run variability. In this paper, we focus on Cray machines and investigate potential causes for performance variability such as OS jitter, shape of the allocated partition, and interference from other jobs sharing the same network links. Reducing such variability could improve overall throughput at a computer center and save energy costs.
Tumor endothelium selectively supports binding of IL-2-propagated tumor-infiltrating lymphocytes. (1995)

Entrance of activated T cells into the tumor after adoptive transfer is a prerequisite for the efficacy of this form of immunotherapy. Because lymphocyte binding to vascular endothelium is the critical step in which lymphocyte extravasation into the tissue is controlled, we compared adhesion of tumor-infiltrating lymphocytes (TIL) to endothelial cells in tumors, peripheral lymph nodes, mucosa-associated lymphatic tissues, and inflamed synovium. Simultaneously, expression of the known homing-associated Ags both on TIL and tumor vasculature was analyzed. All TIL strongly expressed alpha 4-integrins, LFA-1 and CD44, whereas only a low level of L-selectin expression was detected. Tumor vasculature showed signs of activation in each patient on the basis of elevated levels of intercellular adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1, and/or peripheral lymph node addressin (PNAd). TIL showed significantly enhanced binding to tumor vasculature in comparison with other endothelial specificities. Increased binding was not markedly due to up-regulation of the inflammation-induced endothelial cell adhesion molecules in tumors, because binding to inflamed synovium that expressed the same adhesion molecules was not enhanced. In summary, TIL show preferential binding to tumor vasculature and the binding is partially mediated by currently unknown mechanisms. In vitro analysis of endothelial cell binding properties may help to identify those TIL populations that will have the best potential to home back to tumor tissue after adoptive transfer.