gebhart/patrepeval huggingface dataset:
Adaptive Human-Aware Robot Navigation in Close Proximity to Humans (2011)

For robots to be able coexist with people in future everyday human environments, they must be able to act in a safe, natural and comfortable way. This work addresses the motion of a mobile robot in an environment, where humans potentially want to interact with it. The designed system consists of three main components: a Kalman filter-based algorithm that derives a person's state information (position, velocity and orientation) relative to the robot; another algorithm that uses a Case-Based Reasoning approach to estimate if a person wants to interact with the robot; and, finally, a navigation system that uses a potential field to derive motion that respects the person's social zones and perceived interest in interaction. The operation of the system is evaluated in a controlled scenario in an open hall environment. It is demonstrated that the robot is able to learn to estimate if a person wishes to interact, and that the system is capable of adapting to changing behaviours of the humans in the environment.
Using Cohesion and Coherence Models for Text Summarization (1998)

In this paper we investigate two classes of techniques to determine what is salient in a text, as a means of deciding whether that information should be included in a summary. Weintroduce three methods based on text cohesion, which models text in terms of relations between words or referring expressions, to help determine how tightly connected the text is. We also describe a method based on text coherence, which models text in terms of macro-level relations between clauses or sentences to help determine the overall argumentative structure of the text. The paper compares salience scores produced by the cohesion and coherence methods and compares them with human judgments. The results show that while the coherence method beats the cohesion methods in accuracy of determining clause salience, the best cohesion method can reach 76% of the accuracy levels of the coherence method in determining salience. Further, two of the cohesion methods each yield signi cant positive correlations with the human salience judgments. We also compare the types of discourse-related text structure discovered by cohesion and coherence methods.
Synthesis, Characterization, and Application of Ultrasmall Nanoparticles (2013)

Nanomaterials in the size range of 3–50 nm have received increased attention in the last few decades because they exhibit physical properties that are intermediate to those of individual molecules and bulk materials. Similarly, ultrasmall nanoparticles (USNPs), with sizes in the 1–3 nm range, exhibit unique properties distinct from those of free molecules and larger-sized nanoparticles. These properties are greatly sensitive to both the composition and size of the particles, and thus, the ability to control the synthesis for both of these variables is of paramount importance. This review summarizes various methods for the synthesis of USNPs of metals, metal oxides, and metal chalcogenides as well as recent advances in the development of unique characterization methods for these USNPs. Last is a discussion of several novel applications of USNPs in biomedical imaging, catalysis, and semiconductor development, all of which benefit from the large surface-to-volume ratio and/or other characteristic properties inherent in USNPs.
A Structural Role for Glutamine 214 in Human Thymidylate Synthase (1998)

Studies of the crystal structures of thymidylate synthase (TS) have revealed that a kink is present in beta-sheets that form the core of the enzyme. The beta-kink is proposed to serve as a "hinge" during conformational changes that occur in the enzyme after ligand binding at the active site. A residue in one of the beta-bulges that form the kink, glutamine at position 214 of human TS, is highly conserved in all TSs and is postulated to interact with nucleotide ligands that bind at the active site. To examine the role of this residue, glutamine at position 214 was replaced by residues that differ in volume, hydrophobicity, electrostatic charge, and hydrogen bonding potential. Genetic complementation studies utilizing a TS-deficient bacterial strain revealed that residues with large side chain volumes or that are prohibited in beta-bulges created loss of function proteins. Kinetic studies indicated that residue hydrophobicity is not correlated with catalytic activity. Residues that are predicted to alter the charge at position 214 created enzymes with kcat/Km values at least 10(3) lower than those of the wild type. Kinetic and ligand binding studies indicated that residue 214 is involved in nucleotide binding; however, hydrogen bonding potential does not contribute significantly to nucleotide binding energy. The data are consistent with the hypothesis that residue 214 is involved in maintaining the enzyme in a conformation that facilitates nucleotide binding and catalysis.
Photoinduced electron transfer in linked ruthenium(II) diimine-diquat complexes: linkage dependence (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotoinduced electron transfer in linked ruthenium(II) diimine-diquat complexes: linkage dependenceChong K. Ryu, Renyi Wang, Russell H. Schmehl, Sue Ferrere, Maria Ludwikow, Jon W. Merkert, Christine E. L. Headford, and C. Michael ElliottCite this: J. Am. Chem. Soc. 1992, 114, 2, 430–438Publication Date (Print):January 1, 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/ja00028a006https://doi.org/10.1021/ja00028a006research-articleACS PublicationsRequest reuse permissionsArticle Views286Altmetric-Citations64LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Graphene Synthesis <i>via</i> Magnetic Inductive Heating of Copper Substrates (2013)

Scaling graphene growth using an oven to heat large substrates becomes less energy efficient as system size is increased. We report a route to graphene synthesis in which radio frequency (RF) magnetic fields inductively heat metal foils, yielding graphene of quality comparable to or higher than that of current chemical vapor deposition techniques. RF induction heating allows for rapid temperature ramp up/down, with great potential for large scale and rapid manufacturing of graphene with much better energy efficiency. Back-gated field effect transistors on a SiO2/Si substrate showed carrier mobility up to ∼14 000 cm(2) V(-1) s(-1) measured under ambient conditions. Many advantages of RF heating are outlined, and some fundamental aspects of this approach are discussed.
Leaching of a gold bearing partially roasted sulphide. Laboratory scale studies (2001)

This research aimed at defining a route for recovering precious metals from a very heterogeneous gold bearing sulphide and arsenide concentrate that was partially roasted and dumped by the 1960s when Santo António mine closed. Gold occurs in this concentrate as free particles in the range of 10-100 mum, most of them still enclosed in the pyrite and arsenopyrite matrix. Its content varies from 20 to 150 g of Au/ton, being higher at the dump upper levels and in the finer concentrate fractions. Preliminary tests demonstrated the refractoriness of this product, since the leaching with conventional cyanide solutions and with other leaching solutions gave very low recoveries. However, high concentrated cyanide solutions recover more than 60% of Au, although with high NaCN and lime consumptions and poor settling characteristics. Iron was shown to be highly dissolved in these solutions. Some prior treatments clearly favoured the cyanidation process, in particular a roasting step. Thus, a large number of roasting experiments was carried out to define the most favourable conditions for recovering gold. However, no clear relationship between roasting conditions and gold dissolution was found due to the heterogeneity of the product and high variance of gold experimental recoveries. These recoveries were calculated considering gold contained in both the leaching residues and leachates, and uncertainties of these results are relatively high. Roasting the product at 450-700 °C for 1 h guarantees a high probability to dissolve at least 74% Au in a highly concentrated NaCN solution stirred for 24 h. The 600-700 °C roasting range is clearly preferable for consuming less cyanide and lime. Pre-washing the roasted product seems not to reduce the cyanide consumption. Regarding the silver recovery, the NaCN and lime consumption are higher while using the products roasted at the lowest tested temperatures. Products roasted at higher temperatures have better settling performance.
A Single-Arm, Proof-Of-Concept Trial of Lopimune (Lopinavir/Ritonavir) as a Treatment for HPV-Related Pre-Invasive Cervical Disease (2016)

ISRCTN Registry 48776874.
Semantics and knowledge grids: building the next-generation grid (2004)

Just as the Internet is shifting its focus from information and communication to a knowledge delivery infrastructure, we see the Grid moving from computation and data management to a pervasive, worldwide knowledge management infrastructure. We have the technology to store and access data, but we seem to lack the ability to transform data tombs into useful data and extract knowledge from them. We review some of the current and future technologies that will impact the architecture, computational model, and applications of future grids. We attempt to forecast the evolution of computational grids into what we call the next-generation grid, with a particular focus on the use of semantics and knowledge discovery techniques and services. We propose a comprehensive software architecture for the next-generation grid, which integrates currently available services and components in Semantic Web, Semantic Grid, P2P, and ubiquitous systems. We'll also discuss a case study that shows how some new technologies can improve grid applications.
Prevention of monocyte adhesion and inflammatory cytokine production during blood platelet storage: Anin vitro model with implications for transfusion practice (2000)

A novel platelet additive solution [ThromboSoltrade mark (TS)] was designed to allow extended refrigerated platelet storage. It has been shown to preserve platelet function and prevent cytokine accumulation in platelet concentrates stored for up to 9 days. It consists of amiloride, adenosine, sodium nitroprusside, dipyridamole, quinacrine, and ticlopidine. We hypothesized that the cytokine inhibition may be due to prevention of monocyte (MC) adhesion and activation on the surfaces of platelet storage bag plastic polymers. In an in vitro model, we incubated purified peripheral blood MCs on discs of polyolefin and polyvinylchloride from platelet storage bags, and on polystyrene, in the presence of TS for up to 7 days. We found that after incubation with TS, adherent MC numbers were decreased by >80-95% compared with controls on all surfaces examined. Levels of cytokines [interleukin (IL)-1beta, IL-1RA, IL-6, IL-8, and tumor necrosis factor-alpha] were low in wells with TS but rose progressively in the controls during incubation. Amiloride alone had similar effects on adhesion and cytokine release as the complete TS preparation. Removing amiloride from TS abrogated these effects. These findings suggest an important role for TS and amiloride in monocyte function, and have implications for the development of agents designed for prolonged platelet storage.
A quantitative assessment of chemical perturbations in thermotropic cyanobiphenyls (2016)

Chemical programming of the temperature domains of existence of liquid crystals is greatly desired by both academic workers and industrial partners. This contribution proposes to combine empirical approaches, which rely on systematic chemical substitutions of mesogenic molecules followed by thermal characterizations, with a rational thermodynamic assessment of the effects induced by chemical perturbations. Taking into account the similarities which exist between temperature-dependent cohesive Gibbs free energy densities (CFEDs) and pressure-temperature phase diagrams modeled with the Clapeyron equation, chemical perturbations are considered as pressure increments along phase boundaries, which control the thermotropic liquid crystalline properties. Taking the familiar calamitic amphiphilic cyanobiphenyl-type mesogens as models, the consequences of (i) methyl substitution of the aromatic polar heads and (ii) connections of bulky silyl groups at the termini of the apolar flexible alkyl chain on the melting and clearing temperatures are quantitatively analyzed. Particular efforts were focused on the translation of the thermodynamic rationalization into a predictive tool accessible to synthetic chemists mainly interested in designing liquid crystals with specific technological applications.
Realisation of immittance functions with complexsingularities by means ofmodified Antoniou GIC (1995)

The Antoniou general immittance convertor (GIC) has been widely used in the active simulation of inductances. However, when only resistors and capacitors are used in its structure, the simulated immittance function has all singularities on the real negative axis in the complex plane. A modified version of the Antoniou GIC, to obtain immittance functions with both real and complex poles and zeros, is proposed.
Applications and Challenges of Real-time Mobile DNA Analysis (2018)

The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA sequencing outside of laboratory, leading to faster and more accessible DNA-based diagnostics. However, portable DNA sequencing and analysis are challenging for mobile systems, owing to high data throughput and computationally intensive processing performed in environments with unreliable connectivity and power.
Connexin43 and astrocytic gap junctions in the rat spinal cord after acute compression injury (1997)

To examine the possible role of interastrocytic gap junctions in the maintenance of tissue homeostasis after spinal cord damage, we initiated studies of the astrocytic gap junctional protein connexin43 (Cx43) in relation to temporal and spatial parameters of neuronal loss, reactive gliosis, and white matter survival in a rat model of traumatic spinal cord injury (SCI). Cx43 immunolocalization in normal and compression-injured spinal cord was compared by using two different sequence-specific anti-Cx43 antibodies that have previously exhibited different immunorecognition properties at lesion sites in brain. At 1- and 3-day survival times, gray matter areas with mild to moderate neuronal depletion exhibited a loss of immunolabeling with one of the two antibodies. At the lesion epicenter, these areas consisted of a zone that separated normal staining distal to the lesion from intensified labeling seen with both antibodies immediately adjacent to the lesion. Loss of immunoreactivity with only one of the two antibodies suggested masking of the corresponding Cx43 epitope. By 7 days post-SCI, Cx43 labeling was absent with both antibodies in all regions extending up to 1 mm from the lesion site. Reactive astrocytes displaying glial fibrillary acidic protein (GFAP) appeared by 1 day and were prominent by 3 days post-SCI. Their distribution in white and gray matter corresponded closely to that of Cx43 staining at 1 day, but less so at 3 days when GFAP-positive profiles were present at sites where Cx43 labeling was absent. By 7 days post-SCI, Cx43 again co-localized with GFAP-positive cells in the surviving subpial rim, and with astrocytic processes on radially oriented vascular profiles investing the central borders of the lesion. The results indicate that alterations in Cx43 cellular localization and Cx43 molecular modifications reflected by epitope masking, which were previously correlated with gap junction remodeling following excitotoxin-induced lesions in brain, are not responses limited to exogenously applied excitotoxins; they also occur in damaged spinal cord and are evoked by endogenous mechanisms after traumatic SCI. The GFAP/Cx43 co-localization results suggest that during their transformation to a reactive state, spinal cord astrocytes undergo a transitional phase marked by altered Cx43 localization or expression.
Hydroxyurea treatment inhibits proliferation of Cryptococcus neoformans in mice (2012)

The fungal pathogen Cryptococcus neoformans (Cn) is a serious threat to immunocompromised individuals, especially for HIV patients who develop meningoencephalitis. For effective cryptococcal treatment, novel antifungal drugs or innovative combination therapies are needed. Recently, sphingolipids have emerged as important bioactive molecules in the regulation of microbial pathogenesis. Previously we reported that the sphingolipid pathway gene, ISC1, which is responsible for ceramide production, is a major virulence factor in Cn infection. Here we report our studies of the role of ISC1 during genotoxic stress induced by the antineoplastic hydroxyurea (HU) and methyl methanesulfonate (MMS), which affect DNA replication and genome integrity. We observed that Cn cells lacking ISC1 are highly sensitive to HU and MMS in a rich culture medium. HU affected cell division of Cn cells lacking the ISC1 gene, resulting in cell clusters. Cn ISC1, when expressed in a Saccharomyces cerevisiae (Sc) strain lacking its own ISC1 gene, restored HU resistance. In macrophage-like cells, although HU affected the proliferation of wild type (WT) Cn cells by 50% at the concentration tested, HU completely inhibited Cn isc1Δ cell proliferation. Interestingly, our preliminary data show that mice infected with WT or Cn isc1Δ cells and subsequently treated with HU had longer lifespans than untreated, infected control mice. Our work suggests that the sphingolipid pathway gene, ISC1, is a likely target for combination therapy with traditional drugs such as HU.
Enzymatic method for assaying calcium in serum and urine with porcine pancreatic alpha-amylase (1994)

We developed a kinetic assay for calcium in serum and urine, based on the activation of porcine pancreatic alpha-amylase (EC 3.2.1.1) with 2-chloro-4-nitrophenyl-alpha-maltotrioside as substrate. The kinetic generation of 2-chloro-4-nitrophenol, monitored at 405 nm, was proportional to the concentration of calcium in serum and urine. The assay was developed and evaluated with the Cobas Bio centrifugal analyzer. The average within-run and between-day imprecision (CV) was 0.96/1.26% and 1.07/1.63%, respectively, for serum calcium and 1.50/2.54% and 1.70/2.64%, respectively, for urine calcium. Results of the proposed method (y) correlated well with those determined by atomic absorption spectrophotometry (x): y(serum) = 1.005x + 0.028 mmol/L (Sy/x = 0.058, r = 0.974, n = 50), and y(urine) = 1.017x-0.115 mmol/L Sy/x = 0.30, r = 0.981, n = 25). We also present data showing that the method is highly sensitive, rapid, relatively free of interference, and amenable to automation.
世界王牌特种部队独家系列报道（14）：荷兰KCT突击队 (2002)

志愿加入突击队的人经过12周的考验就能得到最基本的武器装备．急救品和作战指导。这一基本突击队训练课程只是志愿者从加入到获得KCT的绿色贝雷帽并成为突击队的一员这一漫长道路中的第一步。
Role of acidosis, NMDA receptors, and acid-sensitive ion channel 1a (ASIC1a) in neuronal death induced by ischemia (2008)

This review collects data on the influence of intracellular and extracellular acidosis on neuronal viability and the effect of acidosis on neuronal damage progressing under brain ischemia/hypoxia. Particular attention is devoted to the involvement of ionotropic glutamic receptors and acid-sensitive ion channel 1a in these processes.
A Regional System to Provide Timely Access to Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction (2007)

Rapid transfer of STEMI patients from community hospitals up to 210 miles from a PCI center is safe and feasible using a standardized protocol with an integrated transfer system.
Thermal radiation of lamellar metal-dielectric metamaterials and metallic surfaces (2015)

We studied angular distributions and spectra of thermal radiation of lamellar metal/dielectric metamaterials with hyperbolic dispersion and compared them with the corresponding characteristics of simple metallic films and pairs of metallic and dielectric layers. The spectra of thermal radiation, in the mid-infrared part of the spectrum, were nearly flat and featureless, in a good agreement with the model predictions. The angular distributions of thermal emission deviated from the predictions of the Kirchoff’s law and closely followed the Lambert’s law, ∝cosθ. The thermal radiation properties of hyperbolic metamaterials were not much different from those of simpler metallic structures.
Conformation and association of pancreatic polypeptide from three species (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformation and association of pancreatic polypeptide from three speciesMilton E. Noelken, Paul J. Chang, and Joe R. KimmelCite this: Biochemistry 1980, 19, 9, 1838–1843Publication Date (Print):April 1, 1980Publication History Published online1 May 2002Published inissue 1 April 1980https://pubs.acs.org/doi/10.1021/bi00550a017https://doi.org/10.1021/bi00550a017research-articleACS PublicationsRequest reuse permissionsArticle Views89Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts