gebhart/patrepeval huggingface dataset:
An intelligent multi-layered input scheme for phonetic scripts (2002)

We introduce a new scheme for stylus-based input of phonetic scripts such as Indic, using a compact smart soft-keyboard. Phonetically related characters are grouped into layers and become dynamically available when the "group-leader" character is accessed. This scheme allows rapid input using taps and flicks. We have developed a prototype for Devanagari which covers the complete script using just 21 virtual keys, and preliminary tests indicate that it is very easy to use with little or no training.This scheme seems to be optimal for compact keyboarding of phonetic scripts, such as Indic, on hand-held and mobile devices. It can be extended to other phonetic scripts such as IPA. It can also be used equally well as an alternate, simpler soft keyboard for conventional desktop systems.
Modeling and analysis of computer power systems (2003)

Two techniques for time-domain analysis, cycle-by-cycle simulation of switched linear circuits and state-space averaging, are discussed in the context of modeling computer power systems. These techniques are compared by studying the output voltage response of a single DC-to-DC power converter to a transient load. Measured data are used to validate the simulated results. Simulation CPU times are also presented along with a discussion on the pros and cons of each approach. Predicting the response to line and load transients of a much larger system composed of three paralleled DC-to-DC converters is studied using state-space averaged models implemented in SPICE.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A model for multimedia service creation and activation (2002)

The emergence of multimedia applications requires appropriate management and control activities to be provided and organized in an integrated framework. This paper presents an architectural approach for the modeling of service activation processing in a multimedia environment. In particular, activation processes complying with this model provide the user with the capability of devising, creating and controlling the required composite multimedia service by using elementary services provided by the network as building blocks. The model introduced in the paper has been effectively used as a basis for the development of a network environment providing prototypal services of Multimedia Cooperative Editing (MCE).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Computer-aided design of a Si avalanche photodiode (1969)

A computer-aided design of a Si avalanche photodiode is presented. As an example, the design of the boron diffused photodiode with a desired time constant is carried out. The choice of an area of an active region is not affected by a diffusion condition but primarily by a substrate impurity concentration. For a very high speed response a moderate substrate impurity concentration must be selected. For a longer time constant than about 0.1 ns an increasing area of an active region is acceptable with a decreasing substrate impurity concentration. In a lightly doped substrate, a uniform multiplication of an active region cannot occur. Using the usual diffusion technique the acceptable highest resistivity of a substrate is about 1-2 Ω.cm. The capacitance of the guard ring occupies a considerable part in a total capacitance. Calculated results are in good agreement with experimental results.
Concerning the Future of the NSF (1992)

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Rationally Designed Multifunctional Supramolecular Iminium Catalysis: Direct Vinylogous Michael Addition of Unmodified Linear Dienol Substrates (2014)

The development of a direct vinylogous Michael addition of linear nucleophilic substrates is a long-standing challenge because of the poor reactivity and the considerable difficulty in controlling regioselectivity. By employing a rationally designed multifunctional supramolecular iminium catalysis strategy, the first direct vinylogous Michael addition of unmodified linear substrates to α,β-unsaturated aldehydes, to afford chiral 1,7-dioxo compounds with good yields and excellent regio- as well as enantioselectivity, has been developed.
Ranking community answers by modeling question-answer relationships via analogical reasoning (2009)

The method of finding high-quality answers has significant impact on user satisfaction in community question answering systems. However, due to the lexical gap between questions and answers as well as spam typically existing in user-generated content, filtering and ranking answers is very challenging. Previous solutions mainly focus on generating redundant features, or finding textual clues using machine learning techniques; none of them ever consider questions and their answers as relational data but instead model them as independent information. Moreover, they only consider the answers of the current question, and ignore any previous knowledge that would be helpful to bridge the lexical and semantic gap. We assume that answers are connected to their questions with various types of latent links, i.e. positive indicating high-quality answers, negative links indicating incorrect answers or user-generated spam, and propose an analogical reasoning-based approach which measures the analogy between the new question-answer linkages and those of relevant knowledge which contains only positive links; the candidate answer which has the most analogous link is assumed to be the best answer. We conducted experiments based on 29.8 million Yahoo!Answer question-answer threads and showed the effectiveness of our approach.
Quantitative analysis of diurnal variation in volume and water content of lumbar intervertebral discs (1998)

The Cavalieri method of modern design stereology has been used in combination with magnetic resonance imaging (MRI) to obtain unbiased estimates of the volume of the lumbar intervertebral discs immediately at the end of a day of normal activity and again following a night's rest. In addition, pixel-by-pixel mapping of the T2-relaxation time has been used to characterize objectively the tissues of the intervertebral discs. The mean increase in height of seven female subjects of average age 21 years (range 19-23 years) measured with a stediometer was 19.3 mm (range 8-26 mm). Image analysis showed that the mean overnight increase in volume of lumbar discs was 1300 mm3 (range 100-2700 mm3). The increase in volume of the disc was accompanied by an increase in the T2-relaxation time of the nucleus pulposus. This suggests that the change in disc volume is most probably caused by a preferential increase in the water content of the nucleus pulposus.
Some Inclusion Relations Associated with Generalized Fractional Differintegral Operator (2013)

A generalized fractional differintegral operator is used to define some new subclasses of analytic functions in the open unit disk . For each of these new function classes, several inclusion relationships are established.
Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction (2012)

Infection with the hepatitis B virus (HBV) promotes the development of hepatitis, cirrhosis, and hepatocellular carcinoma (HCC) and is a leading cause of morbidity and mortality worldwide. HBV X protein (HBx) is an important effector for HBV pathogenesis, but its cellular targets and acting mechanisms remain elusive. We show here that HBx interacts with the anti-apoptotic proteins Bcl-2 and Bcl-xL through a Bcl-2 homology 3 (BH3)-like motif in mammalian cells. Importantly, mutations in the BH3-like motif that prevent HBx binding to Bcl-2 and Bcl-xL abrogate cytosolic calcium elevation and cell death induced by HBx expression in hepatocytes and severely impair HBV viral replication, which can be substantially rescued by restoring cytosolic calcium. These results suggest that HBx binding to Bcl-2 family members and subsequent elevation of cytosolic calcium are important for HBV viral replication. Consistently, RNAi knockdown of Bcl-2 or Bcl-xL results in reduced calcium elevation by HBx and decreased viral replication in hepatocytes. Our results suggest that HBx targets Bcl-2 proteins through its BH3-like motif to promote cytosolic calcium elevation, cell death, and viral replication during HBV pathogenesis, which presents an excellent therapeutic intervention point in treating patients with chronic HBV.
Access to Macrocycles with an endo Aryl Ether and an endo Aryl-Aryl Bond, Development and Application (2011)

Macrocyclization methodologies allowing access to macrocycles having an endo aryl ether and an endo aryl-aryl bond, especially those based on an intramolecular S(N)Ar reaction and the Suzuki-Miyaura reaction, are summarized. Total synthesis of complestatin, a bis-macrocyclic natural product, featuring these two technologies are presented.
Putting the brakes on conciliation hearing dismissals : labour law (2008)

The recent decision by the LAC in Premier of Gauteng & others v Ramabulana NO & others [2008] JOL 21316 (LAC), means that a conciliator may not dismiss a dispute referred to the CCMA or a bargaining council merely because the referring employee failed to make an appearance at the conciliation hearing.
JUMPA Vol.3 No.2 Juni 2016 ANALISIS STRATEGI BISNIS PT. WILTAR USAHA GRUP (2016)

The floating docks are starting to need for the people who live in coastal areas. Factors of the tides is very difficult when they want to go to sea. The floating dock manufacturers PT.Wiltar Usaha Grup is providing a floating dock, but PT. Wiltar Usaha Grup is not the only manufacturer of a floating dock in Indonesia, this company should have competition between other companies. To achieve competitive advantage needed the right business strategy. Based on analisis SWOT at PT. Wiltar Usaha Grup. Finding result finds market penetration strategies as the best alternative business strategy. This strategy is derived from the analysis of internal and external factors using SWOT matrix analysis, analysis of internal-external matrix, grand strategy matrix analysis and SPACE matrix analysis.
3D underground reconstruction for real-time and collaborative virtual reality environment (2018)

Urban planning has become a relevant issue to achieve the sustainable development of the modern cities. It requires ubiquitous systems including 3D GIS capabilities and high performance without many hardware requirements. This paper deals with the development of a web application to visualize, interact and explore, through 3D perspective, the underground infrastructures of our college campus. Its 3D reconstruction raises many challenges which remains to be surmounted. The main aim of this research is the 3D modeling of underground infrastructure in order to real-time analytics of its current features. In addition, this system supports virtual reality technology to interact with the GIS data into a collaborative environment available to be performed with mobile platforms.
Vascular Endothelial Growth Factor-induced Migration of Multiple Myeloma Cells Is Associated with β1 Integrin- and Phosphatidylinositol 3-Kinase-dependent PKCα Activation (2002)

In multiple myeloma (MM), migration is necessary for the homing of tumor cells to bone marrow (BM), for expansion within the BM microenvironment, and for egress into the peripheral blood. In the present study we characterize the role of vascular endothelial growth factor (VEGF) and beta(1) integrin (CD29) in MM cell migration. We show that protein kinase C (PKC) alpha is translocated to the plasma membrane and activated by adhesion of MM cells to fibronectin and VEGF. We identify beta(1) integrin modulating VEGF-triggered MM cell migration on fibronectin. We show that transient enhancement of MM cell adhesion to fibronectin triggered by VEGF is dependent on the activity of both PKC and beta(1) integrin. Moreover, we demonstrate that PKC alpha is constitutively associated with beta(1) integrin. These data are consistent with PKC alpha-dependent exocytosis of activated beta(1) integrin to the plasma membrane, where its increased surface expression mediates binding to fibronectin; conversely, catalytically active PKC alpha-driven internalization of beta(1) integrin results in MM cell de-adhesion. We show that the regulatory subunit of phosphatidylinositol (PI) 3-kinase (p85) is constitutively associated with FMS-like tyrosine kinase-1 (Flt-1). VEGF stimulates activation of PI 3-kinase, and both MM cell adhesion and migration are PI 3-kinase-dependent. Moreover, both VEGF-induced PI 3-kinase activation and beta(1) integrin-mediated binding to fibronectin are required for the recruitment and activation of PKC alpha. Time-lapse phase contrast video microscopy (TLVM) studies confirm the importance of these signaling components in VEGF-triggered MM cell migration on fibronectin.
Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras (1999)

Vascular endothelial growth Factor (VEGF) has been identified as a key angiogenic factor involved in the growth and malignant progression of tumours. Glioblastoma multiforme (GBM) are the most common primary human brain tumours, histo-pathologically characterized by intense tumour angiogenesis. GBMs do not harbour oncogenic Ras mutations, but there is a functional up-regulation of Ras signaling through activation of receptor tyrosine kinases overexpressed by these tumours. We demonstrate that Ras pathway activation regulates VEGF secretion in astrocytoma cell lines. Ras pathway inhibition was carried out using genetic and pharmacologic techniques. Astrocytoma cells that were transfected to express the dominant inhibitory mutant H-Ras(N17) demonstrated a reduction in VEGF secretion under both normoxic and hypoxic conditions. Cells treated with the farnesyl transferase inhibitor L-744,832 demonstrated similar reductions in VEGF secretion. Furthermore, astrocytoma cells expressing a constitutively phosphorylated and truncated EGF-R common in GBMs (EGFRvIII or p140(EGF-R)) demonstrate further elevations in Ras activation, resulting in a further increase in VEGF secretion. We have previously demonstrated that activation of Ras plays a vital role in transducing mitogenic signals in human malignant astrocytoma cells. Our present results further extend the role of Ras activation in modulating tumour angiogenesis in these tumours. We propose that Ras may contribute to the angiogenic switch in astrocytomas.
General phrase speaker verification using sub-word background models and likelihood-ratio scoring (2002)

The authors present a design and study the performance of a text-dependent speaker verification system using general phrase passwords. The text of the password utterance and its phone transcription are assumed to be available. The problems that are addressed include the appropriate choice of units for building target speaker models and the choice of background models for likelihood-ratio scoring.
2015년 여성의 사회적 지위향상 점검지표 분석 (2015)

This research analyzed statistical changes and characteristics, and factors for changes of 46“Indicators for Improvement of Women’s Social Status” in...
Interpenetrating polymer networks containing gelatin modified with PEGylated RGD and soluble KGF: Synthesis, characterization, and application in <i>in vivo</i> critical dermal wound (2007)

The purpose of this study was to evaluate the biocompatibility and the efficacy in wound healing of a gelatin-based interpenetrating polymer network (IPN) containing poly(ethylene glycol) (PEG)-ylated RGD and soluble KGF-1 (RGD-IPN+KGF). IPNs were applied to full-thickness wounds on a rat model. Wound healing was assessed through histological grading of the host response and percent area contraction at 2 days, 1 week, 2 weeks, and 3 weeks. A control IPN containing unmodified gelatin (unmod-IPN) and a conventional clinical bandage were applied to similar wounds and also evaluated. During the first week of healing, the unmod-IPN and conventional dressing wound showed a greater amount of contraction than that of RGD-IPN+KGF. However, by 3 weeks the extent of wound contraction was comparable between treatments. The RGD-IPN+KGF treated wound demonstrated lower macrophage and fibroblast densities at 3 weeks as compared to unmod-IPN treated wounds. RGD-IPN+KGF acted as a tissue scaffold while preventing the entry of foreign bodies, advantages not seen with the conventional dressing. The extent of cellularity and extracellular matrix organization was higher for wounds healed with RGD-IPN+KGF than those healed with unmod-IPN. These results indicate that both soluble and immobilized bioactive factors can be incorporated into our IPN platform to enhance the rate and the quality of dermal wound healing.
The character of the muscarinic receptors in different regions of the rat brain (1980)

The binding characteristics of muscarinic receptors have been critically examined in six regions of the rat brain. The binding curves of antagonists are similar for all six areas but the binding curves of agonists show large differences. It is shown that in all regions there are three classes of receptors with similar binding characteristics but that these are present in different proportions. The binding constants to the three receptor types of a range of agonists were examined and evidence was produced in support of the theory that the subclasses of brain receptors are due to a single receptor subunit subject to different conformational constraints.
Amplification of femtosecond pulses in a passive, all-fiber soliton source (1992)

We report a theoretical and experimental study of the amplification of femtosecond soliton pulses generated by a passively mode-locked fiber laser in a high-gain erbium-doped fiber amplifier (EDFA). Results on the spectral and temporal evolution of 450-fs soliton pulses propagating within an EDFA are presented. Power gains as high as 30 dB and the generation of sub-100-fs Raman colored solitons are observed. The results are found to be well described by the theoretical model presented.
Tetranucleotide repeat polymorphism at the CRYG1 locus (1991)

Tetranucleotide repeat polymorphism at the CRYG1 locus C.M. Hearne, C.M. Hearne Nuffield Department of Surgery, John Radcliffe HospitalHeadington, Oxford OX3 9DU, UK Search for other works by this author on: Oxford Academic PubMed Google Scholar J.A. Todd J.A. Todd * Nuffield Department of Surgery, John Radcliffe HospitalHeadington, Oxford OX3 9DU, UK *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 19, Issue 19, 11 October 1991, Page 5450, https://doi.org/10.1093/nar/19.19.5450-a Published: 11 October 1991
Computerized Axial Manometry of the Esophagus (1987)

This is a presentation of a new manometric parameter of the mechanical competence of the lower esophageal sphincter (LES), the lower esophageal sphincter vector volume (LESVV). It is determined by computer analysis of continuous-pressure measurements during constant speed pullback of a radially oriented 4- 6- or 8-channel manometry catheter across the LES. Patients were studied with this method both before aggressive medical therapy for esophagitis and before and after Nissen fundoplication. LESVV accurately predicted failure of medical therapy and success of the fundoplication. In patients with successful fundoplication, LESVV demonstrated a 100-fold increase in mechanical competence of the LES, even in the absence of increased LES pressure or length, increasing from 113 +/- 63 mm3 to 11357 +/- 3733 mm3.
Building services in Harbour City, Hong Kong (1986)

Harbour City is the largest development of its kind in Hong Kong and comprises two hotels of international standard, each containing approximately 450 rooms, four office towers containing approximately 110,000 m2 of first quality office space, and five residential towers providing 380 luxury apartments of varying sizes. A single continuous three-deck podium of 100,000 m2 accommodates a major department store, restaurants of both Western and Chinese cuisine and genera/ shops, boutiques and other banking and commercial facilities.
Effect of UV System Modifications on Disinfection Performance (1999)

Numerical simulations have been performed to gain a better understanding of ultraviolet (UV) disinfection process performance. Similar simulations in previous studies revealed critical paths through which particles moved and experienced low UV doses. In vertical UV systems, these paths generally are found near the channel walls with characteristics of high velocity and low turbulence intensity. Moreover, these paths generally coincide with low UV intensity zones and appear to represent the primary limitation of process performance. Reactor modifications have been designed to eliminate or modify these trajectories, thereby improving process performance. In a pilot-scale open-channel system with a vertical lamp orientation, two geometric modifications with “wave” and “baffle” shapes have been developed and examined. The results of these pilot tests confirmed the improvement of process performance when compared with an unmodified UV system. As in the case of the unmodified UV systems, a numerical model that combines kinetic information from a well-mixed batch reactor with a dose-distribution function was used to predict process performance of the UV system with the wave-shaped modification. A dose-distribution function that incorporates the effects of spatial nonuniformities in both hydrodynamics (through a random-walk model) and UV intensity (through a point-source-summation model) was developed. The dose-response function for microorganisms was obtained from completely mixed batch reactor experiments with a collimated beam. Predictions of disinfection efficacy confirmed the ability of the modified systems to improve microbial inactivation.
Cu-Sn binary metal particle generation by spray pyrolysis (2016)

Cu-Sn binary particles were generated via spray pyrolysis from metal salt precursors with ethylene glycol as the co-solvent and reducing agent. The morphology, crystallinity, and elemental distribution of particles were tunable by changing the reaction temperature, residence time, and quench gas flow rate. Hollow porous particles were fabricated with a higher Sn concentration on the particle surface when the furnace set point was 500°C, while solid particles with a lower surface Sn concentration were generated when the furnace set point was 1000°C. Particles with spherical morphologies were obtained at long residence time conditions (4.5 s). Cu-Sn binary particles with irregular structures (e.g., pores on the particle surface, fragmented spherical particles, and lamellar fragments) were formed at short residence time conditions (0.92 s). A possible spray pyrolysis mechanism was proposed that incorporates chemical reaction steps and structural progression. By this mechanism, the metal salts are believed to sequentially undergo hydrolysis to metal hydroxides, decomposition to metal oxides, reduction to metals, and finally diffusion of Sn into the Cu matrix to generate the Cu-Sn solid solution. Copyright © 2017 American Association for Aerosol Research
Safety of intracavitary urokinase with percutaneous abscess drainage. (1993)

Intracavitary urokinase can be given safely during percutaneous drainage of an abscess, with no associated bleeding complications or changes in coagulation parameters.