gebhart/patrepeval huggingface dataset:
A System of Mining Semantic Trajectory Patterns from GPS Data of Real Users (2019)

Positioning devices allow users’ movement to be recorded. The GPS (Global Positioning System) trajectory data typically consists of spatiotemporal points, which make up the major part of the big data concerning urban life. Existing knowledge extraction methods about the trajectory share a general limitation—they only investigate data from a spatiotemporal aspect, but fail to take the semantic information of trajectories into consideration. Therefore, extracting the semantic information of trajectories with the context of big data is challenging pattern recognition task that has practical application prospects. In this paper, a system is proposed to extract the semantic trajectory patterns of positioning device users. Firstly, a spatiotemporal threshold and clustering based pre-processing model is proposed to process the raw data. Then, we design a probabilistic generative model to annotate the semantic information of each trajectory after the pre-processing procedure. Finally, we apply the PrefixSpan algorithm to mine the semantic trajectory patterns. We verify our system on a large dataset of users’ real trajectories over a period of 5 years in Beijing, China. The results of the experiment indicate that our system produces meaningful patterns.
A new median adaptive predictor with applications in subband coding (2002)

This paper presents a new adaptive predictor, developed for lossless differential pulse code modulation full-band and subband image coding. The predictor is based on weighted median filter theory, and is compared, using numerical and graphical methods, with a number of alternative predictor designs, both fixed and adaptive. The performance of the predictors is investigated for two different subband coding methods, sub-sampling and pyramid coding, and is found to be higher than of other predictors for a variety of images.
Gas Analysis (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas AnalysisA. P. HobbsCite this: Anal. Chem. 1958, 30, 4, 778–792Publication Date (Print):April 1, 1958Publication History Published online1 May 2002Published inissue 1 April 1958https://pubs.acs.org/doi/10.1021/ac50163a026https://doi.org/10.1021/ac50163a026research-articleACS PublicationsRequest reuse permissionsArticle Views133Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The interleukin 1beta-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages (1997)

Shigella, the etiological agent of bacillary dysentery, rapidly kills human monocyte-derived macrophages in vitro. Wild-type Shigella flexneri, but not a nonvirulent derivative, induced human macrophage apoptosis as determined by morphology and terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL). Shigella-mediated macrophage cell death was blocked by the peptide inhibitors of caspases, acetyl-Tyr-Val-Ala-Asp-aldehyde (acetyl-YVAD-CHO) and acetyl-Tyr-Val-Ala-Asp-chloromethylketone (acetyl-YVAD-CMK). Protection from apoptosis by YVAD was observed in monocytes matured in the presence or absence of colony-stimulating factors (CSF) like macrophage-CSF or granulocyte-macrophage-CSF. Furthermore, lipopolysaccharide (LPS) or gamma interferon (IFN-gamma) rendered human macrophages partially resistant to Shigella cytotoxicity. Macrophages stimulated with either LPS or IFN-gamma were also protected by YVAD from Shigella-induced cell death. During Shigella infections of human macrophages, interleukin-1beta (IL-1beta) was cleaved to the mature form. IL-1beta maturation was severely retarded by YVAD, indicating that IL-1beta-converting enzyme (ICE; caspase 1) is activated in Shigella-induced apoptosis. The finding that Shigella induces apoptosis in human macrophages by activating ICE supports the hypothesis that the acute inflammation characteristic of shigellosis is initially triggered by apoptotic macrophages which release mature IL-1beta during programmed cell death.
A Memory-Efficient Progressive JPEG Decoder (2007)

Image formats specified by the joint photographic expert group (JPEG) are preferred in many applications, including Internet and digital cameras. Baseline and progressive JPEG are the two of the most popular formats. While the challenge to design a baseline JPEG decoder is mainly the computation complexity, the challenge to design a progressive JPEG decoder imposes on the size of the available working memory and the rate of data transfer between the decoder and the storage. This paper presents a memory-efficient progressive JPEG decoder for embedded systems with limited working memory. Two progressive JPEG rendering flows, one-pass and multi-pass flows, are proposed to improve the most time-consuming data transfer and arithmetic operations during the rendering procedure. The using of dynamically adaptive rendering flow makes proposed progressive JPEG decoder well suited to a wide range of image processing applications in consumer products.
Searching API usage examples in code repositories with sourcerer API search (2010)

We present Sourcerer API Search (SAS), a search interface to find API usage examples in large code repositories. SAS facilitates finding API usage examples by providing three unique features: (i) code snippets view for each result that shows the portions of code where APIs are used; (ii) Tag-cloud view of popular words to facilitate query reformulation, and (iii) filtering results using APIs to narrow search results. Furthermore, SAS uses a code index where each code entity is indexed with terms not only found in the entity but also in other entities having similar API usage. These features make SAS a novel search interface to find API usage examples in code repositories.
Mechanisms of quinolone action and microbial response (2003)

Over the years, chromosomal mapping of the bacterial genome of Escherichia coli has demonstrated that many loci are associated with quinolone resistance, which is mainly a result of chromosomal mutation or alteration of the quantity or type of porins in the outer membrane of Gram-negative bacteria. There has been one report of a small and confined episode of plasmid-mediated resistance to fluoroquinolones, which did not appear to persist. With the increasingly widespread use of an expanding range of fluoroquinolone antibiotics, a range and mix in individual bacterial isolates of the different mechanisms of resistance to fluoroquinolones will undoubtedly be encountered amongst clinically significant bacteria. Currently, transferable resistance is extremely rare and most resistant bacteria arise from clonal expansion of mutated strains. However, it is conceivable that in the future, horizontal gene transfer may become a more important means of conferring resistance to fluoroquinolones.
EFFICIENT EXPRESSION OF GREEN FLUORESCENT PROTEIN GENE IN RICE CELLS (1998)

An expression vector suitable for rice (Oryza sativa L.), pAct1.GFP, was constructed by placing the improved green fluorescent protein (GFP) coding sequence under the control of the actin 1 (Act1) promoter of rice. Embryogenic rice calli derived from the mature embryos were bombarded with gold particles coated with pAct1.GFP. Expression of GFP gene in rice cells was followed by incidentlight fluorescence microscopy in vivo and in real time. Bright green fluorescence signals were visible under blue light 3 to 4 h following bombardment. After 10 to 16 h, the maximum expression of GFP gene was observed in 85% of the calli. Meanwhile, the expression of βglucuronidase (GUS) gene driven by Act1 promoter reached the highest in rice cells 40 to 48 h after transformation. GFP as a sensitive and vital reporter may be used as a replacement for GUS in rice transient expression system. However, no green fluorescence from stable expression of GFP gene was observed in transformants.
V p / V s ratio versus differential stress and rock consolidation — A comparison between rock models and time-lapse AVO data (2007)

Abstract The compressional to shear wave velocity ratio (Vp/Vs) is an important parameter in seismic amplitude versus offset (AVO) analysis, and this parameter plays a key role especially for lithology and fluid prediction methods. The P-wave velocity is a key parameter in traditional pressure prediction methods, because overpressure often results in a velocity reduction. However, for AVO-based pore pressure prediction methods, one expects that the Vp/Vs ratio also is a key parameter. The Hertz-Mindlin geomechanical model predicts a constant Vp/Vs ratio as the differential stress changes in a dry package of identical spheres. Ultrasonic core measurements show increased Vp/Vs ratios as the differential stress decreases, especially for unconsolidated wet sands. Thus, one is likely to assume that the Vp/Vs ratio is dependent on rock consolidation. By combining the Hertz-Mindlin model with the Gassmann model, we show how to obtain a sim-ple rock-physics framework including both the differential stress and the degree of rock consolidation. We use the number of grain-to-grain contacts (coordination number) to represent the rock consolidation. For two field examples, we calibrate this consolidation parameter to in-situ stress conditions, then compare the predicted Vp/Vs ratios for the overpressured reservoir conditions with observed time-lapse AVO changes. The correspondence between modeled and AVO-estimated Vp/Vs ratios is good within the assumed accuracy of the real time-lapse AVO changes. In both cases, we observe an increase in the Vp/Vs ratio as the differential stress decreases. In the first case, a pore pressure increase of 5–7MPa is measured, whereas the other case shows a pressure increase of approximately 15MPa. The first reservoir represents a low-to-medium-consolidated sandstone reservoir of 33% porosity on average, whereas the second reservoir is a more consolidated sand with similar porosities (30%).
A psychologically-governed approach to novel-word pronunciation within a text-to-speech system (2002)

On the basis of previous psychological research, a psychologically motivated approach to the technical problem of novel-word pronunciation within a text-to-speech system is presented. The psychological basis for, and the structure of, the resultant model are outlined. Initial results for a partial implementation are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Nucleation and growth of GaN nanorods on Si (111) surfaces by plasma-assisted molecular beam epitaxy - The influence of Si- and Mg-doping (2008)

The self-assembled growth of GaN nanorods on Si (111) substrates by plasma-assisted molecular beam epitaxy under nitrogen-rich conditions is investigated. An amorphous silicon nitride layer is formed in the initial stage of growth that prevents the formation of a GaN wetting layer. The nucleation time was found to be strongly influenced by the substrate temperature and was more than 30 min for the applied growth conditions. The observed tapering and reduced length of silicon-doped nanorods is explained by enhanced nucleation on nonpolar facets and proves Ga-adatom diffusion on nanorod sidewalls as one contribution to the axial growth. The presence of Mg leads to an increased radial growth rate with a simultaneous decrease of the nanorod length and reduces the nucleation time for high Mg concentrations.
DNA Fingerprinting of <i>Lactobacillus</i> <i>crispatus</i> Strain CTV-05 by Repetitive Element Sequence-Based PCR Analysis in a Pilot Study of Vaginal Colonization (2003)

Lactobacillus crispatus is one of the predominant hydrogen peroxide (H(2)O(2))-producing species found in the vagina and is under development as a probiotic for the treatment of bacterial vaginosis. In this study, we assessed whether DNA fingerprinting by repetitive element sequence-based PCR (rep-PCR) can be used to distinguish the capsule strain of L. crispatus (CTV-05) from other endogenous strains as well as other species of vaginal lactobacilli. Vaginal and rectal lactobacilli were identified to the species level by using whole-chromosome probe DNA hybridization. The DNAs from L. crispatus, L. jensenii, L. gasseri, and an as-yet-unnamed H(2)O(2)-negative Lactobacillus species designated 1086V were subjected to rep-PCR. The results of gel electrophoresis and ethidium bromide staining of the DNA fingerprints obtained were compared. L. crispatus CTV-05 had a unique DNA fingerprint compared to all other lactobacilli. DNA fingerprints for 27 production lots of L. crispatus sampled from 1994 through 2001 were identical to that of the original strain isolated in 1993, suggesting strain stability. In a pilot study of nine women, this DNA fingerprinting method distinguished CTV-05 from other endogenous vaginal lactobacilli prior to and after vaginal capsule use. rep-PCR DNA fingerprinting is useful for strain typing and for evaluating longitudinal loss or acquisition of vaginal lactobacilli used as probiotics.
Fluorescent Pirenzepine Derivatives as Potential Bitopic Ligands of the Human M1 Muscarinic Receptor (2004)

Following a recent description of fluorescence resonance energy transfer between enhanced green fluorescent protein (EGFP)-fused human muscarinic M1 receptors and Bodipy-labeled pirenzepine, we synthesized seven fluorescent derivatives of this antagonist in order to further characterize ligand-receptor interactions. These compounds carry Bodipy [558/568], Rhodamine Red-X [560/580], or Fluorolink Cy3 [550/570] fluorophores connected to pirenzepine through various linkers. All molecules reversibly bind with high affinity to M1 receptors (radioligand and energy transfer binding experiments) provided that the linker contains more than six atoms. The energy transfer efficiency exhibits modest variations among ligands, indicating that the distance separating EGFP from the fluorophores remains almost constant. This also supports the notion that the fluorophores may bind to the receptor protein. Kinetic analyses reveal that the dissociation of two Bodipy derivatives (10 or 12 atom long linkers) is sensitive to the presence of the allosteric modulator brucine, while that of all other molecules (15-24 atom long linkers) is not. The data favor the idea that these analogues might interact with both the acetylcholine and the brucine binding domains.
Activity of a long-acting echinocandin, CD101, determined using CLSI and EUCAST reference methods, against<i>Candida</i>and<i>Aspergillus</i>spp., including echinocandin- and azole-resistant isolates (2016)

The activity of CD101 is comparable to that of other members of the echinocandin class for the prevention and treatment of serious fungal infections. Similar results for CD101 activity versus Candida and Aspergillus spp. may be obtained with either CLSI or EUCAST BMD methods.
Density of fresh and embalmed human compact and cancellous bone (1968)

Abstract This investigation was undertaken to determine the densities of fresh human compact and cancellous bone, with its marrow constituents intact, and compact and cancellous bone taken from embalmed cadavers. The density of 107 bone specimens was determined on the basis of the weight and volume of each specimen. Mean density results were: (1) fresh compact bone, 1.85; (2) fresh cancellous bone, 1.08; (3) embalmed compact bone, 1.85; and (4) embalmed cancellous bone, 1.09. Embalming did not appear to have altered the density of either compact or cancellous bone. It was observed also that the densities of several bone specimens taken from the same area of one bone varied greatly.
Progressive Metastatic Renal Cell Carcinoma Controlled by Continuous 5-Fluoro-2-Deoxyuridine Infusion (1988)

We treated 19 patients with progressive metastatic renal cell carcinoma with continuous infusion of 5-fluoro-2-deoxyuridine, 52 per cent of whom had previously received and failed chemotherapy. Implantable pumps were used for automatic drug delivery. 5-Fluoro-2-deoxyuridine was infused continuously for 14 days at monthly intervals. The starting dose was 0.15 mg. per kg. per day (intravenous) or 0.25 mg. per kg. per day (intra-arterial). Intravenous doses were increased or decreased in increments of 0.025 mg. per kg. per day as permitted by toxicity. Abdominal pain, diarrhea and mucositis limited the intravenous infusion, while malaise, anorexia and hepatic function abnormalities limited intra-arterial infusion. Of 18 evaluable patients we observed 1 complete, 4 partial (objective response rate 28 per cent) and 2 minor responses. The duration of response ranged from 2 to greater than 18 months. During a median follow up of 7.5 months (range 2 to 21 months) only 4 of the 18 patients had objective tumor progression. Over-all survival for the 19 patients was 94 per cent. Continuous infusion of 5-fluoro-2-deoxyuridine may be effective for the treatment of progressive renal cell carcinoma.
Design of the basic rectifier with LC filter to comply with the new edition of the IEC1000-3-2 current harmonic-limit specifications (Edition 2.0) (2003)

This paper deals with the analysis and design of the single-phase basic rectifier with LC filter for compliance with the new edition of the IEC 1000-3-2 regulations (Edition 2.0). The results obtained show that the passive approach described here can comply with the required specifications if a proper inductor value of the filter is selected. Compliance with the new edition of the IEC-1000-3-2 regulation has been studied for those pieces of equipment which can be classified as either Class-A or Class-D. The results obtained have been verified by computer simulation and experimental results.
Calculation of conducted EMI generated by single-ended primary inductance converter (2012)

International audience
NMR Studies of Drugs. Applications of Achiral and Chiral Lanthanide Shift Reagents to Acifran Methyl Ester. LSR Binding to a Multifunctional Substrate. (1994)

Abstract The antihyperlipoproteinemic agent, acifran, has been studied as its racemic methyl ester, 1, by 60 MHz 1H NMR in CDC13 solution at 28±1° with the added achiral lanthanide shift reagent (LSR), tris(6, 6, 7, 7, 8, 8, 8-heptaf luoro-2, 2-dimethyl-3, 5-octanedionato-europium(III), Eu (FOD)3, 2, for spectral simplification, and with the chiral LSRs, tris[3-(heptafluoropropylhydroxymethylene)-(+)-camphorato]europium(III), Eu(HFC)3, 3, and tris[3-(trifluoromethylhydroxymethylene)-(+)-camphorato]europium(III), Eu (FACAM)3, 4, for potential determinations of enantiomeric excess. Relative lanthanide-induced shift (LIS) magnitudes with the three LSRs were interpreted as consistent with major lanthanide binding at the 4-oxo carbonyl, but contrasting behavior in observed enantiomeric shift differences (ΔΔδ) with 3 versus 4 may suggest different bound complex geometries for 3 or 4 with 1.
Azo-bridged covalent porphyrinic polymers (Azo-CPPs): synthesis and CO<sub>2</sub> capture properties (2015)

“N<sub>2</sub>-phobic” azo and porhpyrinic groups leading to high CO<sub>2</sub>/N<sub>2</sub> selectivity at high temperature.
Cell Viability Assays (2016)

This chapter is an introductory overview of the most commonly used assay methods to estimate the number of viable cells in multi-well plates. This chapter describes assays where data are recorded using a plate-reader; it does not cover assay methods designed for flow cytometry or high content imaging. The assay methods covered include the use of different classes of colorimetric tetrazolium reagents, resazurin reduction and protease substrates generating a fluorescent signal, the luminogenic ATP assay, and a novel real-time assay to monitor live cells for days in culture. The assays described are based on measurement of a marker activity associated with viable cell number. These assays are used for measuring the results of cell proliferation, testing for cytotoxic effects of compounds, and for multiplexing as an internal control to determine viable cell number during other cell-based assays.
Mg<sup>2+</sup> Binding to Alkaline Phosphatase Correlates with Slow Changes in Protein Lability (2001)

The in vitro reactivation of unfolded Escherichia coli alkaline phosphatase (AP) in the presence of the two natively bound metals Zn2+ and Mg2+ produces two protein species, characterized by different guanidine hydrochloride denaturation kinetics. The high-lability AP form slowly converts to the low-lability form in a first-order reaction with a characteristic lifetime (inverse rate constant) of approximately 300 h at pH 8.0 and 25 degrees C. Addition of Zn2+ and Mg2+ ligands to (folded) apo-AP also produces two protein species, with denaturation kinetics and a long conversion lifetime similar to those found in refolding AP. In contrast, adding Zn2+ alone to apo-AP produces only the high-lability species with no subsequent structural change, suggesting that Mg2+ binding is the event which is responsible for the production of the low-lability AP. The rate of conversion from high- to low-lability AP was found to be linearly dependent on Mg2+ concentration, indicating that Mg2+ binding is rate limiting for this reaction. Experiments where either Zn2+ or Mg2+ was added first, with the second metal added later, show that Mg2+ binding is slowed by the prior presence of bound Zn2+. Mg2+ binding to Zn-AP also slightly increases the enzymatic activity; however, the extent of formation of the low-lability species is related to the square of the Mg2+-induced activity increase. Thus the binding of two Mg2+ to AP produces the dramatic reduction in the rate of denaturation that characterizes the low-lability species. The data suggest the possibility of long distance intersubunit interactions and a role for Mg2+ in providing "kinetic stability" for AP.
Facial point detection using convolutional neural network transferred from a heterogeneous task (2015)

We present a novel training approach that uses convolutional neural network for facial part detection. In the proposed training procedure, we use the parameters of a network obtained for a heterogeneous task as the initial parameters of the network for a target task. We employ a convolutional neural network for facial part labeling in the heterogeneous task, and then transfer the trained network so as to provide initial parameters of the network for facial point detection. This transfer of network is advantageous in the training for a target task in that 1) the network obtains representation kernels for extraction of facial part regions and 2) the network reduces detection errors at distant positions. The performance of the proposed method applied to BioID and Labeled Face Parts in the Wild datasets is comparable to that of state-of-the art methods. In addition, since our network structure is simple, processing takes approximately 3ms for one face on a standard CPU.