gebhart/patrepeval huggingface dataset:
Wireless access monitoring and control system based on digital door lock (2007)

We propose a novel wireless access monitoring and control system based on the digital door lock, which is explosively used as a digital consumer device. Digital door lock is an electronic locking system operated by the combination of digital key, security password or number codes. This paper presents a prototype of the proposed system and shows a scheme for the implementation. To implement the system with ZigBee network protocol, four types of modules are developed, ZigBee module, digital door lock module, human detection module, and ZigBee relay module. ZigBee module is designed to support wireless sensor network and also used for the ZigBee tag to identify the access objects. Digital door lock module is implemented as a digital consumer device to control the access system as well as locking system. It is very convenient system for the consumers and has extensible and flexible characteristics. That is, it can be used as a home security system by the ZigBee network with additional sensor devices. Therefore, it can be a good practical product for the realization of an access monitoring and control system. It also can be applied to the real market for home networking system. Furthermore, the system can be extended to another service such as a connection between mobile phone and home networking system.
Isomerase and Chaperone Activity of Prolyl Isomerase in the Folding of Carbonic Anhydrase (1992)

Several proteins have been discovered that either catalyze slow protein-folding reactions or assist folding in the cell. Prolyl isomerase, which has been shown to accelerate rate-limiting cis-trans peptidyl-proline isomerization steps in the folding pathway, can also participate in the protein-folding process as a chaperone. This function is exerted on an early folding intermediate of carbonic anhydrase, which is thereby prevented from aggregating, whereas the isomerase activity is performed later in the folding process.
Analog circuit design at and below V<inf>T</inf> + 2V<inf>ds,sat</inf> (2007)

Design methods and architectures for high-performance analog circuitry which operates at supply voltages at and below V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> + 2 V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ds,sat</sub> are developed. A low voltage amplifier is designed using these methods. The amplifier, fabricated in an AMIS 0.5 mum CMOS process with 0.8 V p-channel threshold voltages, is shown to operate at supply voltages as low as 0.75 V with full rail-to-rail input and output operation. The amplifier shows 105 dB of open loop gain and GBW of 0.31 MHz while dissipating 11.5 muW from a 0.8 V supply. The design methods may be used with advanced CMOS processes to further reduce the required analog supply voltage.
Implementing haemophilia care in <scp>S</scp>enegal, <scp>W</scp>est <scp>A</scp>frica (2013)

Summary Despite significant progres on haemophilia care in developed world, this disease remains unknown in many sub‐Saharan African countries. The objectives of this article were to report Senegalese experience on the management of haemophilia care through 18 years of follow‐up. This cohort study included 140 patients (127 haemophilia A, 13 haemophilia B), followed in Dakar's haemophilia treatment centre from 1995 to 2012. Our study reported a prevalence of 2.3/100 000 male births, accounting for 11.6% of what is expected in Senegal. From the period 1995–2003 to 2004–2012, significant progress was seen including 67.9% increase in new patient's identification, 11.3 years reduction in mean age at diagnosis (from 15.5 to 4.2 years), lower mortality rate (from 15.3% to 6.8%) and age at death evolved from 6.5 to 23.3 years. Of the 50 haemophilia A patients who were tested for inhibitor presence, 10 were positive (eight severe and two moderate) that is prevalence of 20%. All patients were low responders since inhibitor titre was between 1.5 and 3.8 BU. Disabilities were seen in 36.5% of patients above 20 years old who had musculoskeletal sequels and 39% had no scholar or professional activities in our setting. Implementing haemophilia care in sub‐Saharan Africa is a great challenge as this disease is not yet counted in national health problems in many countries. Lessons learned from this study show a significant improvement in diagnosis and prognosis parameters. This emphasizes the needs to set up such follow‐up initiatives and to enhance medical and lay cooperation for better results.
The Uniqueness of Solutions for a Kind of B. V. P. of Differential Equations (2003)

This paper investigates the uniqueness of solutions with compact support of a boundary value problem which comes from the study of asymptotic behavior of blow up solution of the degenerate parabolic system.
Novel Biodegradable Polyurethanes for Medical Applications (2000)

Biodegradable polyurethanes with various hydrophilic-to-hydrophobic ratios and potential application for nonadhesive barriers in surgery and/or scaffolds for tissue engineering and bone substitutes were synthesized from polycaprolactone diol, mixtures of polycaprolactone and polyethylene oxide diols, hexamethylene- and/or isophorone diiscocyanates, and 1,4-butane diol or 2-amino-1-butanol chain extenders. The polymers had viscosity-average molecular weights in the range of 24.000 to 130.000 dalton, tensile strengths at break of 4 to 60 MPa, Young's moduli from 7 to 72 MPa, elongation at break of 100 to 950%, and glass transition temperatures in the range of-116 to -41°C. The affinity of polymers towards proteins varied depending on the type of polyol and the chain extender used. The adsorption of proteins from whole blood was highest for the materials based on poly(ε-caprolactone) and those containing 2-amino-1-butanol chain extender. There was no protein adsorption on materials based on mixtures of caprolactone and ethylene oxide polyols independent of the poly(ethylene oxide) molecular weight and the chain extender used. The polymers could be processed into three-dimensional porous scaffolds (membranes and sponges) using a phase-inverse process from solutions consisting of a solvent-nonsolvent system and/or with salt crystals additives.
Viral membrane proteins acquire galactose in trans Golgi cisternae during intracellular transport (1982)

Frozen, thin sections of baby hamster kidney (BHK) cells were incubated with either concanavalin A (Con A) or Ricinus communis agglutinin I (RCA) to localize specific oligosaccharide moieties in endoplasmic reticulum (ER) and Golgi membranes. These lectins were then visualized using an anti-lectin antibody followed by protein A conjugated to colloidal gold. All Golgi cisternae and all ER membranes were uniformly labeled by Con A. In contrast, RCA gave a uniform labeling of only half to three-quarters of those cisternae on the trans side of the Golgi stack; one or two cis Golgi cisternae and all ER membranes were essentially unlabeled. This pattern of lectin labeling was not affected by infection of the cells with Semliki Forest virus (SFV). Infected cells transport only viral spike glycoproteins from their site of synthesis in the ER to the cell surface via the stacks of Golgi cisternae where many of the simple oligosaccharids on the spike proteins are converted to complex ones (Green, J., G. Griffiths, D. Louvard, P. Quinn, and G. Warren. 1981. J. Mol. Biol. 152:663-698). It is these complex oligosaccharides that were shown, by immunoblotting experiments, to be specifically recognized by RCA. Loss of spike proteins from Golgi cisternae after cycloheximide treatment (Green et al.) was accompanied by a 50% decrease in the level of RCA binding. Hence, about half of the RCA bound to Golgi membranes in thin sections was bound to spike proteins bearing complex oligosaccharides and these were restricted to the trans part of the Golgi stack. Our results strongly suggest that complex oligosaccharides are constructed in trans Golgi cisternae and that the overall movement of spike proteins is from the cis to the trans side of the Golgi stack.
Digital Image Processing of Earth Observation Sensor Data (1976)

This paper describes digital image processing techniques that were developed to precisely correct Landsat multispectral Earth observation data and gives illustrations of the results achieved, e.g., geometric corrections with an error of less than one picture element, a relative error of one-fourth picture element, and no radiometric error effect. Techniques for enhancing the sensor data, digitally mosaicking multiple scenes, and extracting information are also illustrated.
Vision-based indoor occupants detection system for intelligent buildings (2012)

In intelligent buildings, practical sensing systems designed to gather indoor occupancy information play an indispensable role in improving occupant comfort and energy efficiency by optimizing control strategies of HVAC (Heating, Ventilation and Air Conditioning) system and lighting system. In this paper we propose a novel method for occupant detection based on video surveillances now widely used in buildings. In our method, a two-staged static detector using both Haar-like and HOG (Histograms of Oriented Gradients) features and a template-based motion analysis module are concatenated to detect the heads of occupants rapidly and effectively. The accuracy can satisfy the requirements of the automation systems in intelligent buildings. Experimental results demonstrate the effectiveness and efficiency of the proposed method.
Stationary-phase mutation in the bacterial chromosome: Recombination protein and DNA polymerase IV dependence (2001)

Several microbial systems have been shown to yield advantageous mutations in slowly growing or nongrowing cultures. In one assay system, the stationary-phase mutation mechanism differs from growth-dependent mutation, demonstrating that the two are different processes. This system assays reversion of a lac frameshift allele on an F' plasmid in Escherichia coli. The stationary-phase mutation mechanism at lac requires recombination proteins of the RecBCD double-strand-break repair system and the inducible error-prone DNA polymerase IV, and the mutations are mostly -1 deletions in small mononucleotide repeats. This mutation mechanism is proposed to occur by DNA polymerase errors made during replication primed by recombinational double-strand-break repair. It has been suggested that this mechanism is confined to the F plasmid. However, the cells that acquire the adaptive mutations show hypermutation of unrelated chromosomal genes, suggesting that chromosomal sites also might experience recombination protein-dependent stationary-phase mutation. Here we test directly whether the stationary-phase mutations in the bacterial chromosome also occur via a recombination protein- and pol IV-dependent mechanism. We describe an assay for chromosomal mutation in cells carrying the F' lac. We show that the chromosomal mutation is recombination protein- and pol IV-dependent and also is associated with general hypermutation. The data indicate that, at least in these male cells, recombination protein-dependent stationary-phase mutation is a mechanism of general inducible genetic change capable of affecting genes in the bacterial chromosome.
Detection of cytomegalovirus in upper gastrointestinal biopsies from heart transplant recipients: comparison of light microscopy, immunocytochemistry, in situ hybridisation, and nested PCR. (1998)

H&E and immunocytochemistry represent the best initial screen for CMV and other diseases in upper gastrointestinal biopsies from heart transplant patients. If H&E and immunocytochemistry were negative, nested PCR could significantly increase the diagnostic yield of clinically relevant CMV infection. In situ hybridisation appeared to have no advantages and some drawbacks compared with immunocytochemistry and PCR.
Life control and health. (1998)

This paper describes the life control and its development, concentrating on relationship between life control and health. The main goal is to review the life control and health among Northern Finnish women and men. Life control and its connections with health and life situation make up the theoretical basis of the work. The definition of life control is based on Antonovsky's theory of a sense of coherence. The concept of life control here includes the following subconcepts: comprehensibility (how understandable are the internal and external environments), manageability (ability to influence one's life course at work and in one's whole life), meaningfulness (one's experiences of the meaning of the present or future events) and life satisfaction and human relationships. Future studies need to explain factors affecting the abilities of individuals to control their lives and reach sensible decisions regarding their health and lives overall. New ways of strengthening life control among those who have become marginalized in relation to society need to be identified. A model of factors relating to life control and relationships between such factors could be constructed.
Physical-virtual tools for spatial augmented reality user interfaces (2009)

This paper presents a new user interface methodology for Spatial Augmented Reality systems. The methodology is based on a set of physical tools that are overloaded with logical functions. Visual feedback presents the logical mode of the tool to the user by projecting graphics onto the physical tools. This approach makes the tools malleable in their functionality, with this change conveyed to the user by changing the projected information. Our prototype application implements a two handed technique allowing an industrial designer to digitally airbrush onto an augmented physical model, masking the paint using a virtualized stencil.
Combining predictions for accurate recommender systems (2010)

We analyze the application of ensemble learning to recommender systems on the Netflix Prize dataset. For our analysis we use a set of diverse state-of-the-art collaborative filtering (CF) algorithms, which include: SVD, Neighborhood Based Approaches, Restricted Boltzmann Machine, Asymmetric Factor Model and Global Effects. We show that linearly combining (blending) a set of CF algorithms increases the accuracy and outperforms any single CF algorithm. Furthermore, we show how to use ensemble methods for blending predictors in order to outperform a single blending algorithm. The dataset and the source code for the ensemble blending are available online.
Surgery of state patients in private hospitals – a free lunch? (2020)

As the saying goes, ‘the best things in life are free’ but this is hardly true for orthopaedic surgery. Theatre nursing scrub staff shortages have led to prolonged turn-around times and resistance to starting cases after 15h00 in our state hospitals. This has negatively impacted productivity with surgical volume reduced by at least 25% on our elective lists this year. With the overwhelming demand due to failing services in some provinces and poor socioeconomic factors forcing more patients from private to state care, our elective waiting lists continue to grow.1
Linear-dendritic copolymers/indoxacarb supramolecular systems: biodegradable and efficient nano-pesticides (2014)

Photodegradable and biocompatible nano-indoxacarb was prepared successfully by encapsulation of indoxacarb with poly(citric acid)-poly(ethylene glycol)-poly(citric acid) (PCA-PEG-PCA) ABA type linear-dendritic copolymers both with (nano-IND/TiO2) and without (nano-IND) TiO2 nanoparticles via supramolecular interactions. Preparation of nano-indoxacarb by both formulae was confirmed using spectroscopy and microscopy analyses. TEM images showed small particles with average sizes of 10 nm for nano-IND and 12 nm for nano-IND/TiO2. Interestingly, the rate of degradation of indoxacarb in both nano-IND/TiO2 and nano-IND exposed to UV and natural light was higher than that for free indoxacarb in the presence of TiO2 nanoparticles. Furthermore, results of bioassay experiments on the model pest showed that the essential dosage of pesticide for pest control significantly decreased when nano-IND and nano-IND/TiO2 were used. Because of the higher loading capacity and slower release rate for indoxacarb from nano-IND than from nano-IND/TiO2, and because TiO2 nanoparticles show toxicity in bioassay experiments, nano-IND is introduced as a promising and eco-friendly pesticide system.
Compact optical interconnects for 100-Gb/s to 1-Tb/s data links (2003)

By using parallel optics, coarse WDM, or the combination of the two, compact multichannel transmitters and receivers are being developed for >100-Gb/s applications ranging from optical backplanes to metropolitan access links.
Azithromycin in the treatment of COVID-19: a review (2020)

Azithromycin presents <i>in vitro</i> activity against SARS-CoV-2 and could act in different points of the viral cycle. Its immunomodulatory properties include the ability to downregulate cytokine production, maintain epithelial cell integrity or prevent lung fibrosis. Azithromycin use was associated with a reduction in mortality and ventilation days in other viral infections. These properties could be beneficial throughout the COVID-19. However, the evidence of its use is scarce and of low quality. Azithromycin has been assessed in retrospective observational studies mainly in combination with hydroxychloroquine, which has shown to provide no benefit. This macrolide presents a well-known safety profile. Upcoming clinical trials will determine the role of azithromycin in the COVID-19 (including the stage of the disease where it offers the greatest benefits and the effect of its combination with other drugs).
Screening for gestational diabetes--analysis by screening criteria. (1984)

A previously studied glucose screening test for gestational diabetes was evaluated by six screening test criteria for appropriateness and cost effectiveness as a widespread screening tool. The test consisted of a serum glucose level in a pregnant patient one hour after 50 g of a glucose solution was ingested. Determination was made of price per case detected and of the number of cases missed when using this test or the oral glucose tolerance test on all prenatal patients or on a selected subset of patients. Screening all pregnant patients aged over 25 years for gestational diabetes with the one-hour glucose screening test is recommended. The need for further evaluation of the sensitivity of this screening test is discussed.
Expression and function of GLUT-1 and GLUT-2 glucose transporter isoforms in cells of cultured rat pancreatic islets. (1992)

We have previously investigated glucose induction of glucokinase, glucose usage and insulin release in isolated cultured rat pancreatic islets (Liang, Y., Najafit, H., Smith, R. M., Zimmerman, E. C., Magnuson, M. A., Tal, M., and Mastchinsky, F. M. (1992) Diabetes (1992) 41, 792-806). Here we studied the expression and function of GLUT-1 and GLUT-2 glucose transporter isoforms, using the same system, i.e. isolated pancreatic rat islets immediately after isolation or cultured in the presence of 3 or 30 mM glucose for as long as 10 days. We found by immunofluorescence microscopy and Western and Northern blot analysis of islet extracts that GLUT-1 expression was induced in islet beta-cells in tissue culture both with low or high glucose present. The induction of GLUT-1 was specific to beta-cells but was not present in all beta-cells and was not detected in alpha-cells. GLUT-2 expression was also specific for beta-cells and was not observed in all beta-cells. Some beta-cells in culture coexpressed GLUT-1 and GLUT-2. The expression of the two glucose transporters was regulated in the opposite direction in response to glucose concentration in the culture medium. GLUT-1 was more effectively induced when glucose was low, and GLUT-2 expression was more pronounced when glucose was high in the culture media. Another difference between the two glucose transporters was that GLUT-2 expression was increased while GLUT-1 expression was decreased as culturing continued as long as 7 days. Thus, after 7 days of culture GLUT-2 expression in beta-cells was nearly the same at low and high glucose, whereas GLUT-1 was practically absent no matter what the glucose level was. In attempts to correlate GLUT-1 and GLUT-2 expression to beta-cell function glucose uptake and glucose-stimulated insulin release in fresh and cultured islets were measured. In freshly isolated islet glucose uptake was estimated to be 100-fold in excess of actual glucose use. Glucose uptake was reduced by 7-day culture to about one-third of that observed in freshly isolated islets no matter what the glucose concentration of the culture media. We conclude that in the present experimental system GLUT-1 and GLUT-2 expression and function are not closely associated with glucose usage rates or the secretory function of beta-cells.
Synthesis and Characterization of Hole-transport Materials in Polysiloxane (2002)

Triphenylamine(TPA) substituted polysiloxane was synthesized as the hole-transporting material. Field dependence of the hole mobility and photoconductivity were measured using the time-of flight and simple DC photocurrent measurement, respectively. We demonstrated that the film of polysiloxane with pendant TPA units higher hole mobility (3.2×10 −5 cm 2 /Vsec at E=6×10 5 ) than that of the conventional poly( N -vinylcarbazole) and carbazole substituted polysiloxane. Further experiments are required to test these new materials as hole transporting layers in photorefractive and electroluminescent devices.
Links Between DNA-Based Diet and Salivary Leptin Hormone Concentration (2018)

Highly personalised dietary advice based on combination of genetic information, such as Single Nucleotide Poly-morphisms (SNPs) and `nudge' theory is an emerging field of research towards a achieving a healthy lifestyle. The aim of this preliminary study is to explore possible links between leptin, a hormone which regulates energy balance on the body and DNA-based diet. A trial composed of 23 subjects was run to investigate whether nutrigenomic links exist for salivary leptin. The collected sample was analysed by ELISA, statistical methods and regression. This study compared leptin concentrations over 8 weeks of Intervention group and Control group, which follow and not follow DNA-based diet respectively. For the Intervention group, there was a trend of decreased leptin concentration, however without any statistical significance. Overall, correlation and statistical significance was found between salivary leptin and calorific intake. Moreover, regression models based on the data showed that leptin levels in saliva can be used to predict Body Mass Index (RMI) of subjects.
Securing systems on the Internet of Things via physical properties of devices and communications (2015)

The Internet of Things (IoT) is an emerging trend that generates many new challenges in security and privacy through the interconnect of ubiquitous devices and services over the Internet. Depending on the device and its strict constraints in the IoT, one often needs to refrain from implementing costly public key cryptography to solve the key distribution problem. In this context, Physical Unclonable Functions (PUF) have been identified as a promising replacement that uses already present physical properties of the device. For encryption and authentication services, we combine this technology with Physical Key Generation (PKG) over wireless communication that leverages physical properties of the communications channel. Note that PKG uses same or similar components as PUFs, rendering the combination of both cheap compared to common public-key cryptography such as RSA or ECC. To the best of our knowledge, this is the first approach to combine both technologies to provide confidentiality and authenticity of devices for a lightweight key distribution mechanism. To demonstrate the validity and usefulness of our approach, we derive a generalized architecture for smart home systems and adopt our approach to this scenario.