gebhart/patrepeval huggingface dataset:
Fiber optic pressure sensor (1980)

We propose a new transduction mechanism for fiber optic pressure sensing: pressure-induced microbending, which produces excess optical attenuation in the fiber. A simple bending transducer has been used to determine the response of a step-index multimode fiber to changes in applied pressure. The potential (low frequency) acoustic sensitivity of such a transducer, calculated from this measured response, is approximately 100 μPa into a 1-Hz detection bandwidth.
Genome Sequence of <i>Schizochytrium</i> sp. CCTCC M209059, an Effective Producer of Docosahexaenoic Acid-Rich Lipids (2015)

Schizochytrium is an effective species for producing omega-3 docosahexaenoic acid (DHA). Here, we report a genome sequence of Schizochytrium sp. CCTCC M209059, which has a genome size of 39.09 Mb. It will provide the genomic basis for further insights into the metabolic and regulatory mechanisms underlying the DHA formation.
Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance (2011)

These data demonstrate that increase plasma APOC3 concentrations predispose mice to diet-induced NAFLD and hepatic insulin resistance.
Comparison of unreamed nailing and external fixation of tibial diastases—mechanical conditions during healing and biological outcome (2004)

Locked intramedullary nailing and external fixation are alternatives for the stabilization of tibial shaft fractures. The goal of this study was to determine to what extent the mechanical conditions at the fracture site influence the healing process after unreamed tibial nailing compared to external fixation. A standardized tibial diastasis was stabilized with either a locked unreamed tibial nail or a monolateral fixator in a sheep model. Interfragmentary movements and ground reaction parameters were monitored in vivo throughout the healing period. After sacrifice, the tibiae were examined mechanically and histologically. Bending angles and axial torsion at the fracture site were larger in the nail group within the first five weeks post-operatively. Unlike the fixator group, the operated limb in the nail group did not return to full weight bearing during the treatment period. Mechanical and histomorphometrical observations showed significantly inferior bone healing in the nail group compared to the fixator group. In this study, unreamed nailing of a tibial diastasis did not provide rotational stability of the osteosynthesis and resulted in a significant delay in bone healing.
Delta-doped complementary heterostructure FETs with high Y-value pseudomorphic In/sub 1/Ga/sub 1-y/As channels for ultra-low-power digital IC applications (2002)

The authors report on the device and circuit performance of delta-doped complementary heterostructure insulated gate field effect transistors (C-HIGFETs) which make use of a high InAs mole fraction (y-value) pseudomorphic In/sub y/Ga/sub 1-y/As channel along with a sub-channel delta-doped Si layer to adjust the n-HIGFET and p-HIGFET threshold voltages. Results are presented showing that increasing the y value of the In/sub y/Ga/sub 1-y/As channel up to y=0.25 enhances both the n-HIGFET and the p-HIGFET device performance, as evidenced by the high transconductance values (i.e., G/sub m-n/>300 mS/mm and G/sub m-p/>70 mS/mm, respectively) for 1- mu m gate length devices. The authors present results from In/sub y/Ga/sub 1-y/As channel (y=0.25) C-HIGFET ring oscillators with less than 4- mu W/gate standby-power consumption. These C-HIGFET ring oscillators exhibit gate delays as low as 143 ps at a standby-power of 40 mu W/gate and a switching-power-delay product of 250 fJ. The authors also report on the first fully functional delta-doped C-HIGFET 1 K*4 SRAM operating at a 284-MHz clock frequency and consuming only 183 mW.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Drug delivery system for cancer gene therapy-A review. (2000)

Drug delivery system (DDS), currently employed for cancer gene therapy was reviewed. There have been at least four systems hitherto developed to deliver the anticancer genes to tumor. They include 1) modified liposome system such as cationic liposorne, HVJ-liposme, transferrin conjugated liposome etc. 2) naked plasmid DNA conjugated with ligand or antibody which are known to interact with receptor or antigen on tumor cells. 3) viral vectors such as retroviral vector, adenoviral vector, lenti viral vector, adenoassociated viral vector etc. 4) replication competent oncolytic viruses such as E 1 B attenuated adenovirus or genetically modified herpes simplex virus. Although most of these delivery systems are found to be applicable for local administration of transgene, little success has been reported as to specific targeting to tumor by systemic administration. Therefore efforts are now focusing on the development of devise to target tumor in vivo.
Solid-state reactive sintering mechanism for large-grained yttrium-doped barium zirconate proton conducting ceramics (2010)

A cost-effective solid-state reactive sintering (SSRS) method has recently been developed to synthesize high quality, fully dense, and large-grained yttrium-doped barium zirconate (BZY) ceramic pellets from the raw materials of BaCO3, ZrO2, Y2O3, and NiO, resulting in total proton conductivities as high as 3.3 × 10−2 S·cm−1at 600 °C under a wet argon atmosphere [J. Tong et al., Solid State Ionics, 2010, 181, 496]. In the present work, the mechanisms for the rapid formation of the cubic perovskite phase of BZY, pellet densification, and grain growth during SSRS synthesis are investigated in detail using a suite of experimental techniques. The pre-reaction addition of NiO to the precursor powders is confirmed to accelerate the formation of the cubic perovksite BZYphase. The rapid and full densification of NiO-modified pellets at relatively low temperature (1350 °C) is ascribed to the formation of the impure phase BaY2NiO5 and its subsequent role as a sintering aid. The dramatic further grain growth after densification is facilitated by the partial decomposition of the BaY2NiO5 (which is located primarily at grain boundaries) and its incorporation into the cubic perovskite structure of BZY.
Hexagonal domainlike structure in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mn>1</mml:mn><mml:mi/><mml:mi>T</mml:mi></mml:math>-Ta<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">S</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1983)

X-ray analysis of the nearly commensurate phase of $1T$-Ta${\mathrm{S}}_{2}$ confirms a domainlike structure predicted by a phenomenological charge-density-wave theory. The amplitudes of the atomic displacement waves induced by triple charge-density waves are analogous to those of an ideal domainlike structure consisting of 13 hexagonal domains. In each domain surrounded by discommensurations, 13 Ta atoms construct a star-shaped cluster and the clusters repeat regularly with the period of the $\sqrt{13}a$ structure.
Iterative procedure for designing two-dimensional FIR filters (1987)

We describe a new iterative method to design two-dimensional linear-phase FIR filters with arbitrary magnitude characteristic. The procedure is simple and can be used easily in designing filters of large order. This method is based on the use of the method of projection on to convex sets and can be implemented using the FFT algorithm.
Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor α (WSX-1) (2007)

WSX-1 overexpression in the MRL/lpr background rendered the autoimmune prone mice protected from the development of autoimmune diseases. Our results suggest that IL27 signalling may be a therapeutic target against autoimmune diseases, including human SLE.
The Search for a Reliable MEMS Switch (2013)

The RF community has long been searching for the ideal switch since the birth of electronics, and it is defined as a device having virtually no insertion loss (Ron = 0 Ω) over a wide frequency range, very high isolation [off-state capacitance (Coff)] = 0 fF), extremely high linearity (IIP2 and IIP3 → infinite), medium- to high-power handling (100 mW to 1 kW), and no dc power consumption. Our entire RF infrastructure ecosystem, from communication system networks, to satellite systems, to wideband spectral analysis, to instrumentation and radar systems, uses a variety of switches for signal routing and control (attenuation, phase shifting, etc.). The ideal switch was achieved long time ago using electromechanical relays, and even after nearly 100 years, it is still the best RF switch ever made from an electrical perspective [1]. It has very low insertion loss (Ron <;1 Ω), very high isolation (Coff of few fF), very high linearity and high power handling (100 mW to 50 W). However, it is bulky, expensive, and has an average lifetime of few million cycles.
Short Sleep Duration as a Risk Factor for Hypertension (2006)

Depriving healthy subjects of sleep has been shown to acutely increase blood pressure and sympathetic nervous system activity. Prolonged short sleep durations could lead to hypertension through extended exposure to raised 24-hour blood pressure and heart rate, elevated sympathetic nervous system activity, and increased salt retention. Such forces could lead to structural adaptations and the entrainment of the cardiovascular system to operate at an elevated pressure equilibrium. Sleep disorders are associated with cardiovascular disease, but we are not aware of any published prospective population studies that have shown a link between short sleep duration and the incidence of hypertension in subjects without apparent sleep disorders. We assessed whether short sleep duration would increase the risk for hypertension incidence by conducting longitudinal analyses of the first National Health and Nutrition Examination Survey ( n =4810) using Cox proportional hazards models and controlling for covariates. Hypertension incidence ( n =647) was determined by physician diagnosis, hospital record, or cause of death over the 8- to 10-year follow-up period between 1982 and 1992. Sleep durations of ≤5 hours per night were associated with a significantly increased risk of hypertension (hazard ratio, 2.10; 95% CI, 1.58 to 2.79) in subjects between the ages of 32 and 59 years, and controlling for the potential confounding variables only partially attenuated this relationship. The increased risk continued to be significant after controlling for obesity and diabetes, which was consistent with the hypothesis that these variables would act as partial mediators. Short sleep duration could, therefore, be a significant risk factor for hypertension.
Immunoreactive gastric inhibitory polypeptide and K cell hyperplasia in obese hyperglycaemic (ob/ob) mice fed high fat and high carbohydrate cafeteria diets (1986)

The effect of diet composition on plasma and intestinal concentrations of immunoreactive gastric inhibitory polypeptide (GIP) and intestinal K cell density was examined in obese hyperglycaemic (ob/ob) mice. The mice were reared from 3 to 11 weeks of age on either stock diet, a high fat (HF) cafeteria diet or a high carbohydrate (HC) cafeteria diet. The HF cafeteria diet increased the concentration of GIP in plasma (75%) and in the intestine (118%) and increased the density (54%) of GIP-secreting K cells in the upper jejunum compared with the stock diet. Plasma and intestinal GIP concentrations were not significantly altered by the HC cafeteria diet, although the density of K cells in the upper jejunum was increased (45%). The extent of hyperglycaemia and hyperinsulinaemia in ob/ob mice was not significantly altered by the HF and HC cafeteria diets. The results indicate that an increased amount of dietary fat chronically stimulates the production and secretion of GIP, and enhances intestinal K cell density in ob/ob mice.
Halogenated Kojic Acid Derivatives, Related Compounds, and their Physiological Effects on Plant Growth (1963)

Kojic acid has a slight stimulatory effect on plant growth as measured by the use of duckweed grown under aseptic conditions on a synthetic liquid medium. It is thought that this stimulation is due to the formation of chelatcs. This presentation is primarily concerned with the effect of various derivatives of kojic acid, particularly halogenated derivatives, on plant growth as measured by this same system. Halogenation of the 2-position results in toxic compounds. Substitution in the 6-position results in compounds with beneficial growth effects. Blockage of the 5-position causes a loss of stimulatory ability, interpreted as a loss of chelating power.
[Immune serum globulin E in patients with leukoplakia (author's transl)]. (1979)

Significant changes of humoral factors can occur during the development and growth of malignant tumors. Such can be observed by the periodic recording of immune serum globulin E levels if sensitive RIA methods are employed. Observations of normal persons show largely stable immune serum globulin E levels, and are comparable in patients with leukoplakia of the larynx as well as in patients whose malignant conditions were removed by oepration or radiotherapy. In three patients, a statistically significant increase in serum immune globulin E was recorded immediately before malignant degeneration of known leukoplakia occurred, and was also found in 22 control tumor patients who had experienced local relapses of disease.
First demonstration of high density optical interconnects integrated with lasers, optical modulators, and photodetectors on single silicon substrate (2011)

Engineers are currently facing some technical issues in support of the exponential performance growths in information industries. One of the most serious issues is a bottleneck of inter-chip interconnects. We propose a new "Photonics-Electronics Convergence System" concept. High density optical interconnects integrated with a 13-channel arrayed laser diode, silicon optical modulators, germanium photodetectors, and silicon optical waveguides on single silicon substrate were demonstrated for the first time using this system. A 5-Gbps error free data transmission and a 3.5-Tbps/cm(2) transmission density were achieved. We believe that this technology will solve the bandwidth bottleneck problem among LSI chips in the future.
Meet Your Librarian! (2016)

Discipline librarians can help you with all sorts of aspects of teaching your course. Â Stop by to find out who your discipline librarian is and how you can work with them to better support students and learning in your course.
Light Harvesting in <i>Anacystis nidulans</i> Studied in Pigment Mutants (1980)

Spontaneous pigment mutants of Anacystis nidulans were self-selected for improved growth in far red light (> 650 nanometers). Questions were asked about those features of the light-harvesting mechanism which altered to give the mutants improved photosynthetic performance in far red. Answers were sought by comparing pigment and reaction center concentrations for the parent and six mutants grown in gold fluorescent and in far red light. Three significant results emerged. The ratio of reaction centers for photoreactions I and II (RC1/RC2) varied by a value of about 2.1 for all clones grown in gold and a value of about 1.1 for all clones grown in far red. Alteration of the ratio was not evident in any of the mutants.Phycobilisome alterations were evident as decreased phycocyanin content in all mutants. In three mutants, allophycocyanin became the major remaining phycobilisome component. Action spectra for photoreactions I and II allowed estimates of chlorophylls serving each of the two reaction centers. Ratios of chlorophylls to reaction centers within each photosystem were chlorophyll I/RC1 = 118 +/- 11 and chlorophyll II/RC2 = 52 +/- 9 for all seven clones grown in both gold and far red light. Remarkable constancy of these ratios, in spite of wide variation in cell material, supports an hypothesis that in A. nidulans there are two chlorophyll proteins, each bearing a reaction center and chlorophylls in fixed ratio.
Unrelated Donor Umbilical Cord Blood Transplantation (UD-UCBT) for Adult Patients with High-Risk Acute Myeloid Leukemia (AML) (2008)

Abstract BACKGROUND: Adult patients with high-risk AML can benefit from allogeneic stem cell transplantation but most lack a suitable sibling or unrelated adult donor. Umbilical cord blood has emerged as an alternative source for stem cell transplantation. OBJECTIVES: The aim of the present study was to evaluate toxicity and efficacy of UD-UCBT for the treatment of high-risk AML in adults as well as to identify, by multivariate analysis, factors affecting transplant outcome. PATIENTS AND METHODS: Forty-four consecutive patients (27 males, 17 females) with a median age of 34 yr (range, 16–52) who underwent UD-UCBT at Hospital Universitario La Fe from 2000 until 2007 were analyzed. Primary high-risk feature was high risk cytogenetics (13), therapy-related AML (3) and two or more cycles to achieve first complete remission (CR1, 10) for patients transplanted in CR1 and salvage treatment for patients in second complete remission (CR2, 6) or more advanced stage of the disease (12). Five patients had failed a previous autologous stem cells transplant (ASCT). Conditioning regimen consisted of thiotepa, busulfan (oral, 8; IV, 36), cyclophosphamide (16) or fludarabine (28), and anti-thymocyte globulin. Cyclosporine and prednisone (37) or cyclosporine and mycophenolate mofetil (7) were used for graft-versus-host disease (GVHD) prophylaxis. Most patients (93%) received an HLA-mismatched cord blood unit with 1 (43%) or 2 (50%) disparities. The median number of total nucleated cells (TNC) and CD34+ cells infused was 2 ×107/kg (range, 1–4.4) and 1.2 ×105/kg (range, 0.1–6), respectively. RESULTS: Cumulative incidence (CI) of myeloid and platelet engraftment was 98% and 72% at a median time of 20 and 54 days respectively. Higher CFU-GM counts at infusion accelerated neutrophil recovery and higher CD34+ cell dose at infusion as well as being in first complete remission (CR1) improved platelet engraftment. CI of acute GVHD grades II–IV and III–IV was 20% and 9%, respectively. CI of chronic and chronic extensive GVHD was 47% and 21%, respectively. CI of non-relapse mortality at 2 years was 38% and was significantly increased in patients transplanted beyond CR1 (53% vs 29%; p = 0.01). With a median follow-up of 19 months (range, 7–75), CI of relapse was 20% at 2 years and was higher in patients beyond CR1 (35% vs 18%; p = 0.02) and in patients receiving a lower TNC dose (39% vs 9%; p = 0.02). Event-free survival (EFS) at 2 years was 42% and was significantly higher for patients in CR1 (53% vs 19%; p &lt; 0.01). CONCLUSIONS: These results show that UD-CBT is a curative alternative for a significant number of patients with high-risk AML. This option should be offered to patients early in the course of their disease to improve outcomes. Apart from disease status, cord blood cell dose affected engraftment and could also influence relapse incidence.
Phylogenetic analysis of fowl adenoviruses (2004)

The sequences of the L1 loop of the hexon protein from representative fowl adenovirus (FAdV) strains of the different European and American collections were determined and compared. This study highlighted the lack of consensus in the numbering of the individual serotypes between the American and the European classifications. An identification system is proposed based on restriction fragment length polymorphism of the hexonA/hexonB polymerase chain reaction product. In addition, new insights into the relationships among FAdV strains are presented and discussed on the basis of phylogenetic analysis of the L1 loops sequences. Six clusters of strains that are supported by high bootstrap values were identified. Three of them are clearly independent, forming groups A, B and C, whereas the three others are clustered in a single 'supergroup', denominated D. Interestingly, the Japanese strain TR22 that is presently classified as European type 5 (species B) could not be assigned to any of the aforementioned clusters and might therefore constitute the sole representative of a seventh cluster.
A Comparison Between Tunable Fbars with an Integrated and with a Discrete Variable MEMS Capacitor (2006)

A comparison between two types of frequency tunable film bulk acoustic resonators (FBARs) is presented in this paper. In both types, the frequency tuning is based on a variable MEMS capacitor connected in series with the piezoelectric resonating layer. The difference is in the embodiment of the capacitor, which can be either a discrete element or an integrated part of the device. It is shown that the integrated approach not only reduces the device area by about half, but also gives better fabrication compatibility, and renders on average a quality factor more than 30% higher than the discrete approach.
Anti-money laundering and counter-terrorist financing threats posed by mobile money (2019)

Purpose The purpose of this paper is to explore the various characteristics of mobile money transactions and the threats they present to anti-money laundering (AML) and counter terrorist financing regimes. Design/methodology/approach A thorough literature review was conducted on mobile money transactions and the associated money-laundering and terrorist financing threats. Four key themes were identified in relations to the three stages of money laundering and effective law enforcement. Findings The findings indicate that as money laundering and terrorist financing transactions continue to gravitate towards the weaknesses in the financial system, mobile money provides yet another avenue for criminals to exploit. Risk factors associated with anonymity, elusiveness, rapidity and lack of oversights were all integral considerations in building an effective AML regime. The use of cash is considered a higher threat than mobile money prior to implementation of systems and controls. Practical implications This rapidly changing environment of how individuals manage their money during transactions is set to further explode globally, which poses new problems for regulators and governments alike. Unless there is a unified concentration to heighten global awareness, the imposing threat of mobile money is set to increase at a rapid rate if appropriate actions are not taken. Originality/value The findings from this study can be used to gain greater insights on mobile money transactions and raise further awareness of the ever-increasing threat to global financial integrity.
Neue reaktive Mikrogele als Träger für Enzyme (1979)

Abstract Durch Copolymerisation von Äthylendimethacrylat und Acrylnitril bzw. Glycidylmethacrylat in Emulsion wurden reaktive Mikrogele mit Durchmessern von ca. 50 nm hergestellt. Durch polymeranaloge Umsetzungen konnten funktionelle Gruppen eingeführt werden (Imidoester bzw. Aldehydgruppen), die als Ankergruppen zur kovalenten Immobilisierung von Enzymen geeignet sind. Es wurden die Enzyme Lactatdehydrogenase, Alkalische Phosphatase und Proteinase K immobilisiert. Da bei den mikrogel‐gebundenen Enzymen keine Diffusionshinderung auftritt, liegen die Restaktivitäten der Enzyme wesentlich höher als bei der Immobilisierung an herkömmlichen quellungsporösen granulären Trägern.