gebhart/patrepeval huggingface dataset:
Coherent and random noise attenuation via multichannel singular spectrum analysis in the randomized domain (2012)

ABSTRACT The attenuation of coherent and random noise still poses technical challenges in seismic data processing, especially in onshore environments. Multichannel Singular Spectrum Analysis (MSSA) is an existing and effective technique for random‐noise reduction. By incorporating a randomizing operator into MSSA, this modification creates a new and powerful filtering method that can attenuate both coherent and random noise simultaneously. The key of the randomizing operator exploits the fact that primary events after NMO are relatively horizontal. The randomizing operator randomly rearranges the order of input data and reorganizes coherent noise into incoherent noise but has a minimal effect on nearly horizontal primary reflections. The randomizing process enables MSSA to suppress both coherent and random noise simultaneously. This new filter, MSSARD (MSSA in the randomized domain) also resembles a combination of eigenimage and Cadzow filters. I start with a synthetic data set to illustrate the basic concept and apply MSSARD filtering on a 3D cross‐spread data set that was severely contaminated with ground roll and scattered noise. MSSARD filtering gives superior results when compared with a conventional 3D f‐k filter. For a random‐noise example, the application of MSSARD filtering on time‐migrated offset‐vector‐tile (OVT) gathers also produces images with higher signal‐to‐noise ratios than a conventional f‐xy deconvolution filter.
Experimental Study on Bioremediation of Contaminated Soil. (2002)

This research focuses on bioremediation method of oily contaminated soil. Three sets of bioremediation experiment were conducted using bioprocessing medicines and water with Pseudomonas mendocina. The best experimental condition for bioremediation of oily contaminated soil is well discussed. Oil concentration in the soil was measured using the gravimetric analysis method after extracting with normal hexane. Moreover, a qualitative analysis of the oily contaminated soil was investigated by means of mass spectroscopy method (GC-MS). The experimental results showed that an attack of bacteria on the oily contaminated soil caused a significant decrease of the TPH density less than 20% from its original value 5600ppm.
Kaapi: A thread scheduling runtime system for data flow computations on cluster of multi-processors (2007)

The high availability of multiprocessor clusters for com-puter science seems to be very attractive to the engineer because, at a first level, such computers aggregate high per-formances. Nevertheless, obtaining peak performances on irregular applications such as computer algebra problems re-mains a challenging problem. The delay to access memory is non uniform and the irregularity of computations requires to use scheduling algorithms in order to automatically balance the workload among the processors. This paper focuses on the runtime support implementa-tion to exploit with great efficiency the computation re-sources of a multiprocessor cluster. The originality of our approach relies on the implementation of an efficient work-stealing algorithm for a macro data flow computation based on minor extension of POSIX thread interface.
Calcification of aortic valve detected incidentally on CT scans: prevalence and clinical significance. (1995)

Aortic valve calcification is a common finding on CT scans and is usually clinically insignificant. Nevertheless, some patients with aortic valve calcification on CT have aortic stenosis, particularly those younger than 55 years old and those with moderately dense aortic valve calcification shown by CT. These patients may benefit from hemodynamic assessment of the aortic valve by echocardiography.
Experiments in semiautonomous registration of disparate spatial data: two new techniques and a model for comparison (2002)

We present two new methods for the semiautonomous registration of spatial data from disparate sources, in particular image and elevation data. One method stems from the synthetic image idea first proposed by Horn and Bachman, while the second is a line alignment technique. The methods estimate the affine transform between digital terrain elevation data (DTED) and aerial photographs from the National High Altitude Photography (NHAP) program. We also propose a novel measure of transform consistency and demonstrate the quality of the results. Both systems are accessed via graphical interfaces which are not described here.
Effects of recombinant human interleukin-3 in aplastic anemia (1990)

In a phase I/II study, nine patients with aplastic anemia were treated with recombinant human interleukin-3 (rhIL-3) to assess the toxicity and biologic effects of this multipotential hematopoietic growth factor. Doses ranging from 250 micrograms/m2 to 500 micrograms/m2 were administered as subcutaneous bolus injections daily for 15 days. An increase in platelet counts from 1,000/microL to 31,000/microL was induced by rhIL-3 in one patient, and an increase in reticulocyte counts by more than 10,000/microL in four patients. The blood leukocyte counts temporarily increased in eight patients 1.5- to 3.3-fold (median, 1.8-fold), mainly due to an increase in the number of neutrophils, eosinophils, lymphocytes, and monocytes. In two patients, bone marrow cellularity increased from 7% to 33% and from 10% to 80%, respectively, but without resulting in a substantial improvement of peripheral blood counts. Mild side effects (headache and flushing) were observed in some patients, while low-grade fever occurred in all patients. Transient thrombocytopenia necessitating discontinuation of rhIL-3 treatment occurred in one patient. In conclusion, rhIL-3 can stimulate hematopoiesis in patients with aplastic anemia; however, no lasting effects were obtained.
Structural Characterization of Carbon Nanotube Arrays Formed in Ultra-Long Nanochannels of Porous Alumina Templates (2005)

The importance of carbon nanotube (CNT) alignment and size distribution in various potential applications has propelled extensive research on the syntheses of CNT arrays via different techniques. Anodic aluminum oxide (AAO) films are ideal templates for the synthesis of highly-ordered nanostructures because they are thermally and chemically stable, with pore size (hence the diameter of the nanostructures formed in the pores) that can be fully controlled The growth of CNTs based on AAO templates generally requires a tedious preparation process for metallic catalysts. Therefore, metal catalysts always cause contamination to the CNTs. In our previous papers, we demonstrated novel methods for preparing CNT arrays in AAO [2] and zeolite [3] templates without using any catalysts at low temperatures. Here, we show our current approach to the synthesis of uniform CNT arrays in the nanochannels of AAO templates (up to 100 m in length and 20nm in diameter with or without closed ends) by thermal pyrolysis of polyethylene glycol (Fig. Since no catalyst is needed, the resultant CNTs are highly pure. The structures of CNT arrays have been studied by highresolution transmission electron microscopy (HRTEM).
An enzyme-linked immunosorbent assay for metalaxyl in foods (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn enzyme-linked immunosorbent assay for metalaxyl in foodsWilliam H. NewsomeCite this: J. Agric. Food Chem. 1985, 33, 3, 528–530Publication Date (Print):May 1, 1985Publication History Published online1 May 2002Published inissue 1 May 1985https://doi.org/10.1021/jf00063a047RIGHTS & PERMISSIONSArticle Views86Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (401 KB) Get e-Alerts Get e-Alerts
Locomotor Primitives in Newborn Babies and Their Development (2011)

How rudimentary movements evolve into sophisticated ones during development remains unclear. It is often assumed that the primitive patterns of neural control are suppressed during development, replaced by entirely new patterns. Here we identified the basic patterns of lumbosacral motoneuron activity from multimuscle recordings in stepping neonates, toddlers, preschoolers, and adults. Surprisingly, we found that the two basic patterns of stepping neonates are retained through development, augmented by two new patterns first revealed in toddlers. Markedly similar patterns were observed also in the rat, cat, macaque, and guineafowl, consistent with the hypothesis that, despite substantial phylogenetic distances and morphological differences, locomotion in several animal species is built starting from common primitives, perhaps related to a common ancestral neural network.
Treating alcoholism: an age-specific intervention that works for older patients. (1996)

Alcoholism occurs in 10 to 15% of the population over age 65 and may be difficult to diagnose. The diagnosis is based on a history aimed at detecting behavioral problems associated with drinking, administering an in-office screening instrument, and conducting tests of liver function and/or mean corpuscular volume. The most effective treatment approach in this population focuses on the stresses of aging and co-existing depression, rather than on alcohol use itself. This approach has been found equally effective in long-standing alcoholics and those who develop a drinking problem in late life. Generally, older alcoholics are very responsive to treatment.
Knowledge Distillation for Multi-task Learning (2020)

Multi-task learning (MTL) is to learn one single model that performs multiple tasks for achieving good performance on all tasks and lower cost on computation. Learning such a model requires to jointly optimize losses of a set of tasks with different difficulty levels, magnitudes, and characteristics (e.g. cross-entropy, Euclidean loss), leading to the imbalance problem in multi-task learning. To address the imbalance problem, we propose a knowledge distillation based method in this work. We first learn a task-specific model for each task. We then learn the multi-task model for minimizing task-specific loss and for producing the same feature with task-specific models. As the task-specific network encodes different features, we introduce small task-specific adaptors to project multi-task features to the task-specific features. In this way, the adaptors align the task-specific feature and the multi-task feature, which enables a balanced parameter sharing across tasks. Extensive experimental results demonstrate that our method can optimize a multi-task learning model in a more balanced way and achieve better overall performance.
ChemInform Abstract: Antitumor Agents. Part 166. Synthesis and Biological Evaluation of 5,6, 7,8‐Substituted‐2‐phenylthiochromen‐4‐ones. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Modified pentamer formation assay for measurement of tacrolimus and its active metabolites: comparison with liquid chromatography–tandem mass spectrometry and microparticle enzyme-linked immunoassay (MEIA-II) (1998)

A modified pentamer formation assay (PFA) for quantification of tacrolimus and active metabolites after extraction from whole blood is described. The lower limit of detection was 2 microg/L. Intraassay precision (CV) was 5.7-13.7%, and the interassay CV was 6. 1-14.9%. Tacrolimus trough concentrations in 104 whole blood specimens from liver and kidney transplant recipients were compared with results from HPLC-tandem mass spectrometry (LC/MS/MS) and microparticle enzyme immunoassay (MEIA-II). Data were analyzed by difference plots and are presented as median (95% confidence intervals) of the method differences. MEIA-II results were on average 2.00 microg/L (range, -0.08 to 5.17 microg/L) higher than LC/MS/MS, whereas PFA results were only 1.07 microg/L (range, -2.62 to 5.33 microg/L) higher. Of 104 specimens tested, 25 displayed differences >/=3 microg/L between MEIA-II and PFA: median difference, 4.65 microg/L (range, 3.01-8.79 microg/L). The corresponding median difference between PFA and LC/MS/MS was -0.91 microg/L (range, -4.11 to 0.85 microg/L), and the difference between MEIA-II and LC/MS/MS was 3.67 microg/L (range, 1.88-6.34 microg/L), suggesting the presence of inactive metabolites that caused a positive bias in the immunoassay. In contrast, similar median differences were observed for the remaining 79 specimens: MEIA-II minus LC/MS/MS, 1.78 microg/L (range, -0.45 to 4.11 microg/L); PFA minus LC/MS/MS, 1.90 microg/L (range, -1.70 to 5.50 microg/L). Active tacrolimus metabolites may have contributed to the higher apparent tacrolimus concentrations in these specimens.
Fresh Osteochondral Allografts for Treatment of Articular Defects in Osteochondritis Dissecans of the Lateral Femoral Condyle in Adults (1994)

Fresh osteochondral allografts were used to patch defects in the lateral femoral condyle in 17 patients with osteochondritis dissecans. The patients included 12 males and five females, ages 16 to 46 years. All had previously undergone other procedures including pinning (4), primary removal of osteochondral fragments (16), and abrasion arthroplasty (14). Defects up to 3 cm in diameter were treated with isotopic grafts and fixed with Herbert screws. Larger defects were treated with crescent-shaped grafts fixed with multiple Herbert screws. Follow-up time ranged from two to nine years. Pain, stiffness, swelling, buckling, and locking were ablated in 16 of the 17 patients. No graft collapse has been noted in these individuals. Verification of graft viability was achieved at periods from six weeks to six years, typically at the time of hardware removal. The only failure occurred in an individual with a 3− × 4.5-cm defect who suffered gross fragmentation which left a large crater. Osteochondritis dissecans of the lateral femoral condyle provides an ideal opportunity for evaluating osteochondral grafts. Sixteen of 17 grafts were a success at two to nine years after surgery.
Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies (2017)

It is now a decade since human induced pluripotent stem cells (hiPSCs) were first described. The reprogramming of adult somatic cells to a pluripotent state has become a robust technology that has revolutionised our ability to study human diseases. Crucially, these cells capture all the genetic aspects of the patient from which they were derived. Combined with advances in generating the different cell types present in the human heart, this has opened up new avenues to study cardiac disease in humans and investigate novel therapeutic approaches to treat these pathologies. Here, we provide an overview of the current state of the field regarding the generation of cardiomyocytes from human pluripotent stem cells and methods to assess them functionally, an essential requirement when investigating disease and therapeutic outcomes. We critically evaluate whether treatments suggested by these <i>in vitro</i> models could be translated to clinical practice. Finally, we consider current shortcomings of these models and propose methods by which they could be further improved.
Determination of Solubility of Styrene in Water and of Water in Styrene (1946)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Solubility of Styrene in Water and of Water in StyreneW.H. LaneCite this: Ind. Eng. Chem. Anal. Ed. 1946, 18, 5, 295–296Publication Date (Print):May 1, 1946Publication History Published online1 May 2002Published inissue 1 May 1946https://pubs.acs.org/doi/10.1021/i560153a009https://doi.org/10.1021/i560153a009research-articleACS PublicationsRequest reuse permissionsArticle Views1562Altmetric-Citations97LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Pipelined sections: a new buffer management discipline for scalable QoS provision (2002)

The techniques used to provide quality of service in packet switched networks are buffer management and packet scheduling. The first line of defense against abusive flows that transmit excessive number of packets is the buffer manager. When the number of packets of a flow exceeds a threshold, new arrivals from that flow will be rejected. This threshold must be set to a level that is sufficiently high to provide specific guarantees to the flow and it must also be minimal so that the buffer manager will detect abusive behavior at the earliest possible moment. A buffer management technique that provides the same guarantees using a lower threshold will be more discriminating because it recognizes flow violations earlier. We present the new pipelined sections buffer management technique that is highly scalable and can provide rate guarantees to leaky bucket constrained flows using very low buffer reservations.
Cholinergic signaling through nicotinic acetylcholine receptors stimulates the proliferation of cervical cancer cells: An explanation for the molecular role of tobacco smoking in cervical carcinogenesis? (2008)

We have analyzed the expression of mRNAs encoding nicotinic acetylcholine receptors (nAChRs) in CaSki, SiHa and HeLa cell lines, which are derived from two squamous and one adenocarcinoma of the cervix, respectively. We detected with reverse transcription-polymerase chain reaction mRNAs for ten of the 16 nAChR subunits, namely strong signals for alpha-5, alpha-7, alpha-9, beta-1 and epsilon, and weak signals for alpha-4, beta-2, beta-4, gamma and delta. We confirmed the translation of alpha-5 and beta-1, corresponding to the two strongest RNA signals, in SiHa and HeLa cells by Western blotting, and the localization of these proteins to the plasma membrane by immunofluorescence. The beta-1 subunit was detected membrane-associated in normal and neoplastic squamous epithelia of the cervix in situ, but appeared to be absent from the underlying mesenchyme and even from adjacent columnar epithelia. These observations suggest that normal and neoplastic cervical squamous epithelial cells express several combinations of the pentameric nAChRs. We also measured that the proliferation of SiHa and HeLa cells is stimulated by nicotine. This indicates that cholinergic signaling under normal physiological conditions and stimulated by nicotine in tobacco users affects epithelial homeostasis and neoplastic progression at the cervix in a way similar to the known effects on epithelia of the mouth, the airways and the lung. Since tobacco smoking is established as a risk factor in cervical carcinogenesis, and since nicotine and its derivatives become concentrated in cervical mucus, nAChR-dependent signaling is apparently an important molecular cofactor of human papillomavirus-dependent cervical carcinogenesis.
K-<i>ras</i> Mutations in DNA Extracted From the Plasma of Patients With Pancreatic Carcinoma: Diagnostic Utility and Prognostic Significance (1999)

Plasma K-ras analysis is a highly specific, low-sensitivity approach that has diagnostic and prognostic clinical implications in patients with pancreatic carcinoma.
Phosphoinositide signaling in rat inner medullary collecting duct (1998)

Previous studies in microdissected rat inner medullary collecting duct (IMCD) segments have demonstrated that carbachol, arginine vasopressin (AVP), and the V2 vasopressin receptor agonist 1-desamino-8-D-arginine vasopressin (DDAVP) induce a similar increase in intracellular Ca2+. The present study tested whether these agents activate the phosphoinositide hydrolysis pathway. In intracellular inositol 1,4,5-trisphosphate (IP3) measurements, we found that IMCD suspensions incubated with AVP or DDAVP (10(-8) M) displayed no measurable increase in IP3, whereas IMCD suspensions incubated with the muscarinic cholinergic agent carbachol (100 microM) induced a significant increase in IP3 production. Similarly, carbachol, but not AVP or DDAVP, induced a significant increase in membrane-associated protein kinase C (PKC) enzyme activity. To test what specific PKC isoforms are activated by carbachol in IMCD, we first characterized the PKC isoforms in IMCD suspensions by immunoblotting using affinity-purified antibodies against different PKC isoforms. We identified one classic PKC isoform (alpha), three novel PKC isoforms (delta, epsilon, eta), and one atypical PKC isoform (zeta) in the IMCD. Carbachol induced a cytosol-to-membrane translocation of the PKC-eta isoform but did not alter the distribution of any other isoform. In contrast, AVP had no effect on the distribution of any PKC isoform tested. These data, taken together, demonstrate that carbachol is an activator of the phosphoinositide hydrolysis pathway in IMCD but do not demonstrate signaling via this pathway in response to AVP or DDAVP. These results suggest that the previously observed AVP-stimulated Ca2+ mobilization in IMCD may be due to a mechanism other than activation of the phosphoinositide hydrolysis pathway.
A closed and single‐use system for monocyte enrichment: potential for dendritic cell generation for clinical applications (2003)

The modified cell separator is an easy and fast device to obtain highly enriched MOs with a DC differentiation potential. The system is closed and employs a single-use disposable set and is more amenable to good tissue practice. This method could become a valuable tool for DC-based active immunotherapy.
Waveguide microcavity based on photonic microstructures (1997)

A waveguide based microcavity exhibiting a quality factor Q/spl ap/2500 has been realized by incorporating a /spl lambda//4 phase shift into a 1-D photonic microstructure. The microstructure has an overall length of 3 μm, consists of a deeply etched grating with very narrow (75 nm) air-gaps and exhibits a third-order stop band in the 800-900 nm wavelength regime. A comparison between measurement and simulation suggests that there is a thin (approximately 18 nm) skin of oxidized material at the etched semiconductor-air interfaces.