gebhart/patrepeval huggingface dataset:
Capa, Editorial e Sumário (2018)

A revista CADERNOS MACAMBIRA e um periodico cientifico indexado, de abrangencia multidisciplinar com foco na divulgacao de ANAIS de eventos cientificos nas diferentes areas do conhecimento, apoiados ou organizados pelo Laboratorio de Politicas Publicas, Ruralidades e Desenvolvimento Territorial - LaPPRuDes, pelo IF Baiano, ou mesmo por instituicoes e grupos parceiros. Nesse sentido, sao aceitos resumos simples e expandidos, relatos de experiencias de ensino, pesquisa e /ou de extensao.O cenario atual brasileiro em que se questiona os avancos, mesmo que poucos, conquistados no processo de educacao especial e inclusao escolar, temos a honra de publicar e publicizar a comunidade academica e demais interessados a producao cientifica apresentada durante o IV Seminario Diversidade e Respeito as Diferencas – IV SEDIRD e I Encontro do Grupo de Pesquisa em Educacao Especial na perspectiva da Inclusao Escolar (GPEEPED), realizado pelo Nucleo de Apoio as Pessoas com Necessidades Especificas (NAPNE) do IF Baiano Campus Serrinha e pelo GPEEPED de 06 a 08 de outubro de 2020.Assim, nesta edicao estao contidos 30 trabalhos de 8 eixos tematicos do evento, sendo: agrupados Todos os trabalhos aqui publicados foram avaliados pela comissao cientifica do evento e sao de responsabilidade de seus autores.Os trabalhos cientificos sao aqui apresentados, em formato de artigos e relatos de experiencia, e estao organizados e quatro eixos tematicos, a saber: 04 (quatro) trabalhos do Eixo 1 - Educacao Formal e Informal de Estudantes com Deficiencia Intelectual; 01 (um) trabalho do Eixo 2: Educacao Formal e Informal de Estudantes com Deficiencia Fisica; 05 (cinco) trabalhos do Eixo 3: Educacao Formal e Informal de Estudantes com Deficiencia Auditiva e Surdez; 01 (um) trabalho do Eixo 5: Educacao Formal e Informal de Estudantes com Deficiencias Multiplas; 05 (cinco) trabalhos do Eixo 6: Educacao Formal e Informal deEstudantes com Transtorno do Espectro Autista; 03 (tres) trabalhos do Eixo 7: Educacao Formal e Informal de Estudantes com Altas Habilidades/ Superdotacao; 04 (quatro) trabalhos do Eixo 10: Formacao de professores na area da Educacao Especial; e 07 (sete) trabalhos do Eixo 11: Praticas pedagogicas com estudantes publico da educacao especial e/ou com necessidades especificas.Desejamos a todas e a todos uma boa leitura e convidamos tambem a conhecer e realizar submissao de seus trabalhos a REVISTA MACAMBIRA atraves do site www.revista.lapprudes.net.Aos interessados em publicar os anais de eventos conosco, pode entrar em contato atraves do e-mail: cadernosmacambira@gmail.com.
A highly efficient pipeline for protein expression in Leishmania tarentolae using infrared fluorescence protein as marker (2010)

Leishmania tarentolae, a unicellular eukaryotic protozoan, has been established as a novel host for recombinant protein production in recent years. Current protocols for protein expression in Leishmania are, however, time consuming and require extensive lab work in order to identify well-expressing cell lines. Here we established an alternative protein expression work-flow that employs recently engineered infrared fluorescence protein (IFP) as a suitable and easy-to-handle reporter protein for recombinant protein expression in Leishmania. As model proteins we tested three proteins from the plant Arabidopsis thaliana, including a NAC and a type-B ARR transcription factor. IFP and IFP fusion proteins were expressed in Leishmania and rapidly detected in cells by deconvolution microscopy and in culture by infrared imaging of 96-well microtiter plates using small cell culture volumes (2 μL - 100 μL). Motility, shape and growth of Leishmania cells were not impaired by intracellular accumulation of IFP. In-cell detection of IFP and IFP fusion proteins was straightforward already at the beginning of the expression pipeline and thus allowed early pre-selection of well-expressing Leishmania clones. Furthermore, IFP fusion proteins retained infrared fluorescence after electrophoresis in denaturing SDS-polyacrylamide gels, allowing direct in-gel detection without the need to disassemble cast protein gels. Thus, parameters for scaling up protein production and streamlining purification routes can be easily optimized when employing IFP as reporter. Using IFP as biosensor we devised a protocol for rapid and convenient protein expression in Leishmania tarentolae. Our expression pipeline is superior to previously established methods in that it significantly reduces the hands-on-time and work load required for identifying well-expressing clones, refining protein production parameters and establishing purification protocols. The facile in-cell and in-gel detection tools built on IFP make Leishmania amenable for high-throughput expression of proteins from plant and animal sources.
Adaptive impulse detection using center-weighted median filters (2001)

Previous median-based impulse detection strategies tend to work well for fixed-valued impulses but poorly for random-valued impulse noise, or vice versa. This letter devises a novel adaptive operator, which forms estimates based on the differences between the current pixel and the outputs of center-weighted median (CWM) filters with varied center weights. Extensive simulations show that the proposed scheme consistently works well in suppressing both types of impulses with different noise ratios.
Influence of Location, Fluid Flow Direction, and Tissue Maturity on the Macroscopic Permeability of Vertebral End Plates (2008)

The results from this animal study showed that the central zone of the vertebral endplate was more permeable than the periphery and the flow-out permeability was up to 35% greater than the flow-in permeability. Increase of permeability with decrease of cartilage thickness was noticed within the same age group. We also found a statistically significant decrease of the macroscopic permeability correlated with the tissue maturity.
The Association of the COMT V158M Polymorphism with Endometrial/Ovarian Cancer in HNPCC Families Adhering to the Amsterdam Criteria (2006)

Catechol-O-methyltransferase (COMT) is vital for the conjugation of catechol estrogens that are produced during oestrogen metabolism. The efficiency of this process varies due to a polymorphism in COMT, which changes valine to methionine (V158M). The Met genotypes slow the metabolism of catechol oestrogens, which are agents that are capable of causing DNA damage through the formation of DNA adducts and reactive oxygen species (ROS) production. The slower metabolism of catechol oestrogens results in there being a higher circulating concentration of these oeastrogens and consequently greater probability of DNA damage. To determine whether metabolic inefficiencies of oeastrogen metabolism are associated with the development of malignancy in hereditary non-polyposis colorectal cancer (HNPCC), we studied the V158M polymorphism in COMT in a large cohort of 498 HNPCC patients from Australia and Poland that were either mutation positive (n = 331) or negative (n = 167) for mismatch repair (MMR) gene mutations (hMLH1 or hMSH2). HNPCC is a familial predisposition to colorectal cancer (CRC) and extracolonic cancers that include endometrial cancer.Using Real Time PCR, the COMT V158M polymorphism was examined and its association with disease expression, age of diagnosis of cancer, mutation status and mutation type was assessed in the HNPCC MMR mutation positive and negative groups. This study showed that the V158M polymorphism had no association with disease risk in the HNPCC MMR mutation positive population. However, the polymorphism was significantly associated with endometrial/ovarian cancer risk in HNPCC MMR mutation negative patients (p = 0.002). The heterozygous (Val/Met) genotype was associated with an increased risk of developing endometrial/ovarian cancer whereas the homozygous mutant (Met/Met) showed a decreased risk. The results suggest heterosis, where there is an apparent greater effect of the heterozygous state in this dichotomous trait. In conclusion, this study shows that the COMT V158M polymorphism alters the risk of developing endometrial/ovarian cancer in patients that adhere to the Amsterdam HNPCC criteria but do not have a DNA mismatch repair gene mutation.
CD2-mediated CD59 stimulation in keratinocytes results in secretion of IL-1alpha, IL-6, and GM-CSF: implications for the interaction of keratinocytes with intraepidermal T lymphocytes. (1999)

Normal epidermal keratinocytes are here shown to express membrane-associated complement inhibitory protein CD59 in vitro that protects keratinocytes from damage by complement because preincubation with blocking antibodies to CD59 renders the cells susceptible to complement mediated lysis. CD59 expression in keratinocytes is constitutive and not modulated by inflammatory cytokines, phorbol myristate acetate (PMA), and a number of other agents tested. Antibody mediated cross-linking of CD59, however, revealed an additional function of CD59: keratinocytes in vitro are activated to secrete the cytokines IL-1alpha, IL-6, and GM-CSF. CD59 mediated induction of these cytokines is regulated at the transcriptional level. Binding of keratinocytes to HL60 cells that express CD59 ligand CD2 induced the same pattern of secreted cytokines whereas binding to CD2-negative HL60 cells did not. Induction of cytokine secretion was completely blocked by preincubation of keratinocytes with both anti-CD58 and anti-CD59 antibodies together. The results demonstrate that CD2-mediated CD59 stimulation in human keratinocytes leads to synthesis of a particular set of cytokines implying a potential activation pathway in the interaction of keratinocytes with intraepithelial CD2+ T cells.
Surface wave tomography of the western United States from ambient seismic noise: Rayleigh and Love wave phase velocity maps (2008)

We present the results of Rayleigh wave and Love wave phase velocity tomography in the western United States using ambient seismic noise observed at over 250 broad-band stations from the EarthScope/USArray Transportable Array and regional networks. All available threecomponent time-series for the 12-month span between 2005 November 1 and 2006 October 31 have been cross-correlated to yield estimated empirical Rayleigh and Love wave Green's functions. The Love wave signals were observed with higher average signal-to-noise ratio (SNR) than Rayleigh wave signals and hence cannot be fully explained by the scattering of Rayleigh waves. Phase velocity dispersion curves for both Rayleigh and Love waves between 5 and 40 speriod were measured for each interstation path by applying frequency-time analysis. The average uncertainty and systematic bias of the measurements are estimated using a method based on analysing thousands of nearly linearly aligned station-triplets. We find that empirical Green's functions can be estimated accurately from the negative time derivative of the symmetric component ambient noise cross-correlation without explicit knowledge of the source distribution. The average traveltime uncertainty is less than 1 s at periods shorter than 24 s. We present Rayleigh and Love wave phase speed maps at periods of 8, 12, 16,and 20 s. The maps show clear correlations with major geological structures and qualitative agreement with previous results based on Rayleigh wave group speeds.
Chlamydia pneumoniae (TWAR) infections in children (1994)

From the Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA
Information scent as a driver of Web behavior graphs (2001)

The purpose of this paper is to introduce a replicable WWW protocol analysis methodology illustrated by application to data collected in the laboratory. The methodology uses instrumentation to obtain detailed recordings of user actions with a browser, caches Web pages encoutered, and videotapes talk-aloud protocols. We apply the current form of the method to the analysis of eight Web protocols, visualizing the structure of the interaction and showing the strong effect of information scent in determining the path followed.
A privacy policy model for enterprises (2003)

Privacy is an increasing concern in the marketplace. Although enterprises promise sound privacy practices to their customers, there is no technical mechanism to enforce them internally In this paper we describe a privacy policy model that protects personal data from privacy violations by means of enforcing enterprise-wide privacy, policies. By extending Jajodia et al.'s flexible authorization framework (FAF) with grantors and obligations, we create a privacy control language that includes user consent, obligations, and distributed administration. Conditions impose restrictions on the use of the collected data, such as modeling guardian consent and options. Access decisions are extended with obligations, which list a set of activities that must be executed together with the access request. Grantors allow to define a separation of duty between the security officer and the privacy officer.
Development of a Lesion-Mimic Phenotype in a Transgenic Wheat Line Overexpressing Genes for Pathogenesis-Related (PR) Proteins Is Dependent on Salicylic Acid Concentration (2003)

In the course of coexpressing genes for pathogenesis-related (PR) proteins for a class IV chitinase and an acidic glucanase in transgenic wheat plants, we regenerated a wheat line that developed necrotic lesions containing dead cells in the T2 and subsequent generations. Lesion spots were detected at the booting stage (5- to 6-week-old plants) in lines homozygous for the transgene loci. In contrast, lesions were not observed in hemizygous transgenic lines or lines silenced for transgene expression, indicating a requirement for high levels of transgene expression for the development of the lesioned phenotype. Lesion development was associated with the accumulation of host-encoded PR proteins, e.g., chitinases, beta-1,3-glucanases, thaumatin-like protein, and production of reactive oxygen intermediates. F1 progeny of a cross between the lesion-plus transgenic line and wild-type nontransgenic plants produced progeny with a normal phenotype, while the F2 progenies segregated for the lesion phenotype. Salicylic acid (SA) levels in plants with the lesion-plus phenotype were found to be several times higher than controls and nearly double the levels in hemizygous transgenic plants that lack lesions. SA application activated lesion development in excised leaf pieces of these hemizygous transgenic plants. Similar activation of lesion development in control plants occurred only when high concentrations of SA were applied for prolonged periods. Transcripts for phenylalanine-ammonia lyase, which provides precursors of SA, were elevated in homozygous transgenic plants. Our data suggest that transgene-induced lesion-mimic phenotype correlates with enhanced SA biosynthesis.
Chromatin structure as a mediator of aging (2010)

The aging process is characterized by gradual changes to an organism's macromolecules, which negatively impacts biological processes. The complex macromolecular structure of chromatin regulates all nuclear processes requiring access to the DNA sequence. As such, maintenance of chromatin structure is an integral component to deter premature aging. In this review, we describe current research that links aging to chromatin structure. Histone modifications influence chromatin compaction and gene expression and undergo many changes during aging. Histone protein levels also decline during aging, dramatically affecting chromatin structure. Excitingly, lifespan can be extended by manipulations that reverse the age-dependent changes to chromatin structure, indicating the pivotal role chromatin structure plays during aging.
Multi-layered covert QR codes for increased capacity and security (2015)

Quick Response (QR) codes, used in marketing, warehouse management, product tracking, and other applications, are usually only comprised of visible black and white modules. The goal of this research is the creation of covert, color QR codes for increased data capacity, and security. This goal was met by layering QR codes, each of a unique color, printing the covert versions of the color QR codes, upconverting the covert codes into visible codes and unlayering them to take advantage of the various color channels present. It was shown that color layering of the QR codes effectively increased the data capacity by three times that of a traditional QR code, while the covert nature of the code provides added security. Finally, it was also demonstrated that a layered QR code with six base colors (using color intensity variations) could further increase QR code data capacity.
US humint and comint in the Korean War: From the approach of War to the Chinese intervention (1999)

(1999). US humint and comint in the Korean War: From the approach of War to the Chinese intervention. Intelligence and National Security: Vol. 14, The Clandestine Cold War in Asia, 1945–65: Western Intelligence, Propaganda and Special Operations, pp. 17-63.
Application of Full Waveform Inversion to variable-depth streamer data (2012)

Full Waveform Inversion (FWI) aims to estimate high resolution velocity models by minimizing the difference between observed and modeled seismic waveforms. Good low frequency data plays an important role in the successful application of FWI. Variable-depth streamer acquisition delivers high signal-to-noise (S/N) seismic data over a significantly wider frequency bandwidth than standard streamer acquisition. We show that FWI adapts naturally to the variable-depth acquisition geometry and so benefits from the improved low frequencies recorded in this configuration. Application to data from the Central North Sea reveals detailed velocity features associated with shallow channels in the near surface geology. Migration with this updated velocity model improves the imaging through the near surface.
Structure-Free Data Aggregation in Sensor Networks (2007)

Data aggregation protocols can reduce the communication cost, thereby extending the lifetime of sensor networks. Prior works on data aggregation protocols have focused on tree-based or cluster-based structured approaches. Although structured approaches are suited for data gathering applications, they incur high maintenance overhead in dynamic scenarios for event-based applications. The goal of our work is to design techniques and protocols that lead to efficient data aggregation without explicit maintenance of a structure. As packets need to converge spatially and temporally for data aggregation, we propose two corresponding mechanisms– <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Data-Aware Anycast</i> at the MAC layer and <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Randomized Waiting</i> at the application layer. We model the performance of the combined protocol that uses both the approaches and show that our analysis matches with the simulations. Using extensive simulations and experiments on a testbed with implementation in TinyOS, we study the performance and potential of structure-free data aggregation.
Age-Related 4,977 bp Deletion in Human Lung Mitochondrial DNA (1996)

The accumulation of mitochondrial DNA (mtDNA) mutations has been suggested to be an important contributor to human aging and degenerative diseases. The lung is exposed to ambient air and makes direct contact with the external environment. Numerous potentially noxious agents may damage lung tissues directly or indirectly through free-radical-mediated reactions. In previous studies, we demonstrated an age-dependent increase of mtDNA mutations in various human tissues. We hypothesize that the accumulation of the 4,977 bp (base pairs) deleted mtDNA in human lung tissues is also age-dependent. Using the polymerase chain reaction technique, we determined the incidence of the 4,977 bp-deleted mtDNA in 127 human lung specimens from 34-wk gestation to 79 yr of age. The results showed that 77 lung biopsies (60.6%) contained the 4,977 bp-deleted mtDNA, which started to appear in lung tissues after the fourth decade of life. The incidence apparently increased from 14.3% (one of seven) of the subjects in the 30- to 39-yr age group to 77.8% (two of 27) of the subjects in the 70- to 79-yr age group (p < 0.0001). The mean (+/- SEM) proportion of the 4,977 bp-deleted mtDNA in lung tissues significantly increased from 0.007 +/- 0.007% of the subjects in the 30- to 39-yr age group to 0.833 +/- 0.330% of those in the 70- to 79-yr age group (p < 0.005). Other factors such as sex, pulmonary function indices, and smoking status did not have statistically significant impact on the amount of the deleted mtDNA. These findings suggest that the accumulation of the 4,977 bp-deleted mtDNA is associated with aging human lung.
MECHANICAL PROPERTIES OF CELLULASE-TREATED FABRICS ANALYZED (1997)

Studies were intended to show the best parameters for controlling the finishing effects of celluloses as well as propose a new methodology to compare different finishing routes in terms of their mechanical parameters. Wet processing facilities employ this methodology to compare, optimize and implement processes, as well as to select the best parameters for measuring a particular finishing effect.
Antiaggregation activity of chaperones and its quantification (2013)

Methods for the quantitative estimation of the antiaggregation activity of protein chaperones (first of all, small heat shock proteins) and chemical chaperones including amino acids, carbohydrates, polyamines, and cyclodextrins are discussed. Based on analysis of the plots of light scattering intensity or apparent optical absorption versus time, formulas for calculation of initial rate of aggregation of protein substrate and lag period on kinetic curves of aggregation were derived. Possible determination of the stoichiometry of chaperone-protein substrate complex from the dependence of the initial rate of aggregation on the ratio of protein chaperone/protein substrate concentrations is discussed. To characterize efficiency of the protective action of chemical chaperones, the [L]0.5 value can be used ([L]0.5 is the concentration of a chemical chaperone at which twofold decrease in the initial rate of aggregation occurs). Methods for quantitative estimation of the combined protective action of chaperones are discussed.
Schwerpunkt ′84: Physikalische Forschung mit dem Computer: Monte‐Carlo‐Computer‐Experimente: Ein vielseitiges Werkzeug der Festkörperphysik (1984)

Abstract Seit die Monte‐Carlo‐Methode erstmals 1953 auf ein Problem der statistischen Thermodynamik, die Zustandsgleichung einer „Flüssigkeit”︁ aus harten Scheiben, angewandt wurde, ist sie sowohl für die analytische Theorie als auch für das Experiment als ergänzende Methode unentbehrlich geworden. Ausgehend von einem Modellansatz für atomare Wechselwirkungen, lassen sich statische (und manchmal auch dynamische) Eigenschaften von Vielteilchensystemen simulieren, und dabei wird festgestellt, ob das Modell einem realen Material hinreichend entspricht oder ob eine analytische Näherung genügend genau ist usw. Nach einer kurzen Einführung in die Grundlagen dieser Methode wird anhand konkreter Beispiele aus der Oberflächenphysik, der Physik der Legierungen und des Magnetismus gezeigt, wie aktuelle Fragen der Forschung so einer Lösung nähergebracht werden.
Traveling wave solution for the (2+1) dimensional PKP equation (2010)

In this paper, we derive exact traveling wave solutions of the (2+1) dimensional PKP equation by a presented method. The method appears to be efficient in seeking exact solutions of nonlinear equations.