gebhart/patrepeval huggingface dataset:
A Reliable Scheme for Cluster Storage System (2007)

An important issue in the design of large-scale cluster storage systems is their vulnerability to nodes crash and network failures. To explore the feasibility of implementing a reliable, high performance distributed cluster storage system, we adopt a reliable scheme that data are distributed across storage nodes using erasure coding with small low-density parity-check (LDPC) code. We implement our new scheme in RSC, a proof-of-concept reliable cluster storage system, along with two other well known RAID-1 and RAID-5 schemes. Performance test results show that such a reliable scheme can provide high reliability while keeping the performance overhead small.
Antiplatelet therapy in percutaneous coronary intervention (2008)

The goal of antiplatelet therapy for patients with acute coronary syndromes undergoing percutaneous coronary intervention (PCI) is to reduce the risk of ischaemic events without increasing the risk of bleeding. Aspirin, the most widely used antiplatelet agent, is effective, safe, and inexpensive and is recommended for all patients undergoing PCI. Clopidogrel, the thienopyridine agent, has been shown to reduce the rates of adverse cardiac events and mortality when given in a loading dose before PCI and in a maintenance dose thereafter. It has been extensively studied in patients with non–ST-elevation myocardial infarction (NSTEMI), but less so in patients with ST-elevation myocardial infarction (STEMI). Questions remain as to the optimal loading and maintenance doses of clopidogrel, timing of administration before PCI, and duration of therapy after placement of bare-metal or drug-eluting stents. New, more potent thienopyridines with faster onset of action are in development. Used with PCI, glycoprotein (GP) IIb/IIIa inhibitors reduce the rates of death, myocardial infarction, and urgent target-vessel revascularization in patients with STEMI and NSTEMI. Although GP IIb/IIIa inhibitors are most often used at the time of PCI, early administration in the emergency department or ambulance may improve clinical outcomes. All antiplatelet agents carry a risk of bleeding, which may significantly affect clinical outcomes.
A novel immunohistochemical method for estimating cell cycle phase distribution in ovarian serous neoplasms: implications for the histopathological assessment of paraffin-embedded specimens (2004)

We have investigated whether immunohistochemical markers can identify differences in cell cycle phase distribution in ovarian serous neoplasms, including borderline tumours of different grades. Sections of normal ovary (n=18), serous cystadenoma (n=21), borderline serous tumours (n=21) and serous cystadenocarcinoma (n=15) were analysed by immunohistochemistry using markers of cell cycle entry (Mcm-2) and cell cycle phase, including cyclin D1 (mid-to-late G1), cyclin A (S phase), cyclin B1 (G2 phase) and phosphohistone H3 (mitosis). Double-labelling confocal microscopy confirmed marker phase specificity and phase estimations were corroborated by flow cytometry. On progression from normal ovary through serous cystadenoma and borderline tumours to cystadenocarcinomas, expression of Mcm-2 (P<0.0001), cyclin D1 (P=0.002), cyclin A (P<0.0001), cyclin B1 (P<0.0001) and phosphohistone H3 (P<0.0001) increased, paralleled by an increase in the S-phase fraction (cyclin A : Mcm-2 ratio; P=0.002). Borderline tumours of increasing grade also showed increased Mcm-2 and cyclin A expression, together with an increase in the S-phase fraction. Immunohistochemistry can be used to estimate cell cycle phase distribution in ovarian serous neoplasms, giving results similar to flow cytometric analysis and enabling direct assessment of tumour heterogeneity. Immunohistochemical estimates of the S-phase fraction may identify serous borderline tumours likely to exhibit malignant progression and/or select serous cystadenocarcinomas likely to respond to adjuvant therapy.
T-<i>Broker</i>: A Trust-Aware Service Brokering Scheme for Multiple Cloud Collaborative Services (2015)

Oriented by requirement of trust management in multiple cloud environment, this paper presents T-broker, a trust-aware service brokering scheme for efficient matching cloud services (or resources) to satisfy various user requests. First, a trusted third party-based service brokering architecture is proposed for multiple cloud environment, in which the T-broker acts as a middleware for cloud trust management and service matching. Then, T-broker uses a hybrid and adaptive trust model to compute the overall trust degree of service resources, in which trust is defined as a fusion evaluation result from adaptively combining the direct monitored evidence with the social feedback of the service resources. More importantly, T-broker uses the maximizing deviation method to compute the direct experience based on multiple key trusted attributes of service resources, which can overcome the limitations of traditional trust schemes, in which the trusted attributes are weighted manually or subjectively. Finally, T-broker uses a lightweight feedback mechanism, which can effectively reduce networking risk and improve system efficiency. The experimental results show that, compared with the existing approaches, our T-broker yields very good results in many typical cases, and the proposed system is robust to deal with various numbers of dynamic service behavior from multiple cloud sites.
Influence of immunogenicity on the efficacy of long-term treatment with infliximab in rheumatoid arthritis (2011)

The formation of anti-infliximab Abs during treatment with infliximab is associated with a loss of clinical response, the appearance of infusion reactions and discontinuation of treatment.
Cell line banks and their role in cancer research (1996)

The utility of centralized cell banks in providing reference cultures for cancer research is reviewed. Procedures applied at The American Type Culture Collection in development, maintenance and expansion of such a resource are discussed for example, with emphasis on human tumor cell lines. The various categories of cell-line holdings are explained, and status with regard both to the numbers of lines available and distribution experienced are documented. The locations of other national cell repositories plus contact data are provided.
A Practical System of Telecobalt Radiography (1963)

“Cobaltography” (cobalt-60 telecurieography) is extensively used in radiotherapy departments today, but has been limited to treatment field-verification studies (so-called portal films for localizing treatment portals in their relation to each other and to the site of disease and nearby important viscera). Ideally utilized as an integral component of a telecobalt treatment system, however, cobaltography can serve two additional important functions: (a) depth-dose recording (the portal film furnishing permanent records of the depth dose throughout the irradiated volume) and (b) depth-dose correcting (with densitometrically valid portal films guiding the positioning, shaping, and density of compensating absorbers to be interposed in the radiation treatment beam so as to correct significant inhomogeneities in the irradiated volume). In order to serve the three functions of field verification, dose recording, and inhomogeneity correction, the systems of cobaltography reported by Perryman et al. (1) and subsequently by others (2–8), utilizing Bakelite cassettes, industrial film and lead, or lead and fluorescent intensifying screens, require substantial modification. This is a brief preliminary report of a method suitable for use as an integral component of a telecobalt treatment system (to be described elsewhere). The procedure eliminates cassettes and screens and incorporates the use of nitrogen burst agitation in the film processing. The film used is Eastman Kodak Type M, which is stored, handled, and exposed in Ready-Pak envelopes without transfer into Bakelite cassettes. Since cassettes and screens are not used, identification can be accomplished by pressure desensitization of the emulsion. Writing the patient's name and other worthwhile data on the outside of the Ready-Pak envelopes with a ballpoint pen both identifies the envelope for handling prior to processing and, by emulsion desensitization, permanently labels the portal films, in white if done prior to radiation exposure, and in black if following radiation exposure. After the patient has been positioned in exactly the same relation to the teletherapy apparatus as for actual treatment, the Ready-Pak envelope of appropriate size is placed against the side of the body opposite the treatment portal. A plastic sheet 4 mm. thick and slightly larger than the Ready-Pak envelope is interposed between the patient and the film, closely apposed to the film. This plastic sheet filters out soft scattered electrons and photons which contaminate the transmitted beam, insures electron equilibrium, and protects the film from pressure and other potential sources of artefacts. In addition, it can serve to support the Ready-Pak envelope when exposures are made with the patient upright. For the initial exposure the collimator and secondary beam-shaping devices are positioned exactly as for the actual treatment.
Mediastinitis After Coronary Artery Bypass Graft Surgery (1995)

The present study and a review of the literature suggest that obesity and duration of surgery are the most important predictors of mediastinitis. Furthermore, although the early increase in mortality has been well described, the present study documents for the first time that mediastinitis has a significant negative influence on long-term survival independent of the patient's preoperative condition.
Behavior of thin Ta-based films in the Cu/barrier/Si system (1999)

This work concentrates on the diffusion barrier stability of very thin (10 or 20 nm) α- or β-Ta, TaN, Ta(O) and Ta(N,O) films in the Cu/barrier/Si system. Based on the classical theory of the thin film growth and know how of material transport in thin films, the various Ta-based films were classified according to their density of free short-circuit paths. Using scanning electron microscopy, transmission electron microscopy, glow discharge optical emission spectroscopy and secondary ion mass spectrometry, the 20 nm thin polycrystalline columnar-structured β-Ta films were found to be stable up to 500 °C for 1 h. After 1 h at 600 °C Cu3Si was formed due to short-circuit diffusion of Cu throughout the β-Ta films. The 20 nm thin giant-grained α-Ta films show equivalent performance to the β-Ta films. On the other hand, the 10 nm thin stuffed nanocrystalline face-centered-cubic (fcc) TaN films were able to protect the Si from Cu diffusion up to at least 600 °C/1 h. Ten nm thin amorphous-like Ta(N,O) and Ta(O) films also show barrier stability that is comparable to fcc TaN. While Ta(N,O) tends to recrystallize mainly into hexagonal-close-packed Ta2N above 500 °C, the Ta(O) remains amorphous even at 600 °C. Besides the amorphous-like microstructure, the high recrystallization temperature of Ta(O) is the reason why the introduction of 5 nm thin Ta(O) film into the Cu/5 nm Ta(O)/5 nm β-Ta/Si structure leads to a stability increase up to at least 600 °C for 1 h.
Intensely Luminescent Materials Obtained by Combining Lanthanide Ions, 2,2‘-Bipyridine, and Poly(ethylene glycol) in Various Fluid or Solid Environments (1999)

Steady-state luminescence spectroscopy and luminescence decay analysis have been employed to study the association of two rare earth ions (i.e., Eu3+ and Tb3+) with poly(ethylene glycol) in the absence and in the presence of 2,2‘-bipyridine, which acted as an antenna of near-UV radiation. Three different systems have been studied at various polymer concentrations, i.e., aqueous solutions, transparent composite organic/inorganic sol−gel matrixes made by hydrolysis of tetramethoxysilane, and polymer matrixes. The photophysical behavior of the luminescent species has been studied in conjunction with the poly(ethylene glycol) content. In both aqueous solutions and silica matrixes, luminescence intensity and decay time were found to increase by increasing polymer concentration. Addition of 2,2‘-bipyridine resulted in complex formation between the ligand and the lanthanide ions. This complex was stabilized by association with the polymer chains. Excitation at the ligand absorption wavelength (337 nm) resulted in ligand-to-metal energy transfer and strong luminescence emission, characterized by the narrow-band emission of the metal. The complex between lanthanide ions and 2,2‘-bipyridine possessed its own particular photophysical characteristics and emitted a bright broad blue luminescence with an excitation maximum around 380 nm. Freeze-drying of aqueous solutions of medium size poly(ethylene glycol) containing lanthanide ions and 2,2‘-bipyridine produced an intensely luminescent solid material emitting the characteristic luminescence of the metal when excited at the ligand absorption band (337 nm) or the characteristic luminescence of the complex when excited at 380 nm.
Expression of a cDNA encoding the glucose trimming enzyme glucosidase II in CHO cells and molecular characterization of the enzyme deficiency in a mutant mouse lymphoma cell line (1997)

Glucosidase II is an ER resident glycoprotein involved in the processing of N-linked glycans and probably a component of the ER quality control of glycoproteins. For cloning of glucosidase II cDNA, degenerate oligonucleotides based on amino acid sequences derived from proteolytic fragments of purified pig liver glucosidase II were used. An unamplified cDNA library from pig liver was screened with a 760 bp glucosidase II specific cDNA fragment obtained by RT-PCR. A 3.9 kb glucosidase II cDNA with an open reading frame of about 2.9 kb was obtained. The glucosidase II sequence did not contain known ER retention signals nor hydrophobic regions which could represent a transmembrane domain; however, it contained a single N-glycosylation site close to the amino terminus. All studied pig and rat tissues exhibited an mRNA of approximately 4.4 kb with varying tissue expression levels. The authenticity of the identified cDNA with that coding for glucosidase II was proven by overexpression in CHO cells. Mouse lymphoma PHAR 2.7 cells, deficient in glucosidase II activity, were shown to be devoid of transcripts.
Packaging Very Fast Switching Semiconductors (2014)

The switching speed of power semiconductors has reached levels where conventional semiconductor packages limit the achievable performance due to parasitic inductance and capacitance. Designing these parasitics intentionally is the key to overcome this speed limit. This paper gives an overview on relevant parasitic effects in semiconductor properties, package and switching cell design. A module with extremely low dc link inductance is built up using a newly developed packaging technology. The experimental results lead to a proposal for next step in package design for fast switching and minimizing EMI generation.
Freestanding 2D Arrays of Silver Nanorods (2006)

Freestanding silver nanorods (Ag-NWs) sandwiched between poly(allyamine hydrochloride)/polystyrene sulfonate polyelectrolyte bilayers, (PAH/PSS)10PAHAg(PAH/PSS)10PAH, and suspended over a 150 μm opening (see figure) have been prepared. At a Ag-NW volume fraction of 22.5%, the membrane is both mechanically robust and electrically conductive.
VHF high-power tunable RF bandpass filter using microelectromechanical (MEM) microrelays (2001)

A VHF RF bandpass filter tuned through the use of MEM microrelays was operated at a 25 W RF power input level. The filter insertion loss was less than 1 dB at the tuned frequencies of operation, and the filter operating Q was about 10. The MEM microrelays were life tested for 53 million operating cycles at 25 W RF power, and no significant degradation to the contacts was noted. The development of the microrelay and the use of a CAE tool in the filter development are discussed. © 2001 John Wiley & Sons, Inc. Int J RF and Microwave CAE 11: 261–275, 2001.
Human DNA extraction from whole saliva that was fresh or stored for 3, 6 or 12 months using five different protocols (2017)

In summary, a complicated picture emerges when taking into account the extracted DNA's quantity, purity and quality; depending on a given researchers needs, one protocol's particular strengths and costs might be the deciding factor for its employment.
La pauvreté dans le monde : réponses inopérantes et solutions efficientes (2019)

D’une part, la volonté annoncée de l’ONU en faveur de la réduction de la pauvreté mérite d’être interrogée dans les énoncés qui en résultent. D’autre part, divers exemples nationaux, pris sur plusieurs continents, montrent que certaines réponses qui semblent appropriées à court terme, se révèlent inopérantes à moyen terme. En conséquence la réduction de la pauvreté doit s’appuyer sur d’autres éléments qui forment un triptyque.
Low-cost, disposable microfluidics device for blood plasma extraction using continuously alternating paramagnetic and diamagnetic capture modes (2016)

Blood plasma contains biomarkers and substances that indicate the physiological state of an organism, and it can be used to diagnose various diseases or body condition. To improve the accuracy of diagnostic test, it is required to obtain the high purity of blood plasma. This paper presents a low-cost, disposable microfluidics device for blood plasma extraction using magnetophoretic behaviors of blood cells. This device uses alternating magnetophoretic capture modes to trap and separate paramagnetic and diamagnetic cells away from blood plasma. The device system is composed of two parts, a disposable microfluidics chip and a non-disposable (reusable) magnetic field source. Such modularized device helps the structure of the disposable part dramatically simplified, which is beneficial for low-cost mass production. A series of numerical simulation and parametric study have been performed to describe the mechanism of blood cell separation in the microchannel, and the results are discussed. Furthermore, experimental feasibility test has been carried out in order to demonstrate the blood plasma extraction process of the proposed device. In this experiment, pure blood plasma has been successfully extracted with yield of 21.933% from 75 μl 1:10 dilution of deoxygenated blood.
Processing dual sensor streamer data from an ultradeep water area offshore Guyana (2009)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2009Processing dual sensor streamer data from an ultradeep water area offshore GuyanaAuthors: Jack KinkeadLorin Friedberg CramerQuoi TruongDavid CarlsonJack KinkeadPGS, Lorin Friedberg CramerPGS, Quoi TruongPGS, and David CarlsonPGShttps://doi.org/10.1190/1.3255836 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Abstract Data acquired with dual sensor technology allows one to separate the up‐going from the down‐going wave‐field and yield a product void of the receiver ghost. The bandwidth of this result, benefiting from the absence of the spectral notches induced by the receiver ghost, is then used to produce an improved image for all depths. In the ultra deep water of offshore Guyana, this technology has been utilized, and the images which have been achieved are superior to those obtainable with a streamer configured solely with pressure sensors.Permalink: https://doi.org/10.1190/1.3255836FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 2009ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2009 Pages: 4338 publication data© 2009 Copyright © 2009 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 14 Oct 2009 CITATION INFORMATION Jack Kinkead, Lorin Friedberg Cramer, Quoi Truong, and David Carlson, (2009), "Processing dual sensor streamer data from an ultradeep water area offshore Guyana," SEG Technical Program Expanded Abstracts : 634-638. https://doi.org/10.1190/1.3255836 Plain-Language Summary PDF DownloadLoading ...
Anoctamin/TMEM16 family members are Ca<sup>2+</sup>‐activated Cl<sup>−</sup> channels (2008)

Ca(2+)-activated Cl- channels (CaCCs) perform many important functions in cell physiology including secretion of fluids from acinar cells of secretory glands, amplification of olfactory transduction, regulation of cardiac and neuronal excitability, mediation of the fast block to polyspermy in amphibian oocytes, and regulation of vascular tone. Although a number of proteins have been proposed to be responsible for CaCC currents, the anoctamin family (ANO, also known as TMEM16) exhibits characteristics most similar to those expected for the classical CaCC. Interestingly, this family of proteins has previously attracted the interest of both developmental and cancer biologists. Some members of this family are up-regulated in a number of tumours and functional deficiency in others is linked to developmental defects.
Significance of Ground‐Wafer Management Strategy— A Systems Approach <sup>a</sup> (1969)

Abstract In Southern California's San Bernardino Valley a unique experiment is being performed by a local water district, the State government, and a private industry. Both the experiment and the organizational arrangements for getting the job done are the subject of this paper. The experiment is the application of systems analysis technology to water resource management. The organization is formed by a combination of contracts and cooperative agreement between private and government agencies. The result is a favorable environment for the development of effective water resource management strategies. The San Bernardino Valley is similar Co many areas in the world where water resource management reduces to the allocation of locally available ground water and potential imported water resources. This paper outlines in detail the analysis tools and long‐range planning needs of effective ground‐water management strategies.
Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU (2020)

Our findings emphasize the concern of superinfection in COVID-19 patients due to Acinetobacter baumannii and Staphylococcus aureus. Consequently, it is important to pay attention to bacterial co-infections in critical patients positive for COVID-19.
Gradient Episodic Memory for Continual Learning (2017)

One major obstacle towards AI is the poor ability of models to solve new problems quicker, and without forgetting previously acquired knowledge. To better understand this issue, we study the problem of continual learning, where the model observes, once and one by one, examples concerning a sequence of tasks. First, we propose a set of metrics to evaluate models learning over a continuum of data. These metrics characterize models not only by their test accuracy, but also in terms of their ability to transfer knowledge across tasks. Second, we propose a model for continual learning, called Gradient Episodic Memory (GEM) that alleviates forgetting, while allowing beneficial transfer of knowledge to previous tasks. Our experiments on variants of the MNIST and CIFAR-100 datasets demonstrate the strong performance of GEM when compared to the state-of-the-art.
Gripping Device to Test Brittle Metal Single Crystals in Tension (1956)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Lazarus C. Weiner; Gripping Device to Test Brittle Metal Single Crystals in Tension. Rev. Sci. Instrum. 1 December 1956; 27 (12): 1081. https://doi.org/10.1063/1.1715461 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioReview of Scientific Instruments Search Advanced Search |Citation Search