gebhart/patrepeval huggingface dataset:
Technology for Planar Power Semiconductor Devices Package with Improved Voltage Rating (2008)

The high-voltage SiC power semiconductor devices have been developed in recent years. They cause an urgent in the need for the power semiconductor packaging to have not only low interconnect resistance, less noise, less parasitic oscillations, improved reliability, and better thermal management, but also High-Voltage (HV) blocking capability. The existing power semiconductor packaging technologies includes wire-bonding interconnect, press pack, flip-chip technology, metal posts interconnected parallel plates structure (MIPPS), dimple array interconnection (DAI), power overlay (POL) technology, and embedded power (EP) technology. None of them meets the requirements of low profile and high voltage rating. The objective of the work in this dissertation is to propose and design a high-voltage power semiconductor device packaging method with low electric field stress and low profile to meet the requirments of high-voltage blocking capability. The main contributions of the work presented in this dissertation are: 1. Understanding the electric field distribution in the package. The power semiconductor packaging is simulated by using Finite Element Analysis (FEA) software. The electric field distribution is known and the locations of high electric field concentration are identified. 2. Development of planar high-voltage power semiconductor device packaging method With the proposed structure in the dissertation, the electric field distribution of a planar device package is improved and the high electric field intensity is relieved. 3. Development of design guidelines for the propsed planar high-voltage device packaging method. The influence of the structure dimensions and the material properties is studied. An optimal design is identified. The design guideline is given. 4. Fabrication and experimental verification of the proposed high-voltage device packaging method A detailed fabrication procedure which follows the design guideline is presented. The fabricated modules are tested by using a high power curve tracer. Test results verify the proposed method. 5. Simplification of the structure model of the proposed device package The package structure model is simplified through the elimination of power semiconductor device internal structure model. The simplified model can be simulated by a non-power device simulator. The simulation results of the simplified model match the simulation results of the complete model very well.
Construction of Color Kansei Model Using a Neural Network (2012)

In this study, we focus on the sensitivity characteristic of the L-, M- and S-cones in human color vision, and construct a model that outputs two sets of Kansei values characterized as “bright - dark” and “light - heavy” using a four-layered neural network. In a subjective test, examinees evaluated 64 color patterns on a CRT display using two word pairs on a seven step rating scale. The evaluation results were standardized (min. -0.9, max. 0.9) as the output of the neural network. Three units of the input layer in the network model corresponded to the L-, M- and S-cones, respectively. The values of the absorption spectra characteristics of the L-, M- and S-cones were fed into each input unit. After training, the output of the model for both training results and performance test results were very close to the teaching Kansei values. We confirmed that the model has reproduced human Kansei values for colors. Furthermore, analyzing the synaptic weights values of the neural network model after training, we obtained the units that extracted individual differences of two color experts.
A Reliable Reconfiguration Controller for Fault-Tolerant Embedded Systems on Multi-FPGA Platforms (2010)

This paper proposes the design of a controller managing the fault tolerance of multi-FPGA platforms, contributing to the creation of a reliable system featuring high flexibility and resource availability. A fault management strategy that exploits the devices' reconfiguration capabilities is proposed, the Reconfiguration Controller, focus of this paper, is the main component in charge of implementing such strategy. The innovative points raised by this work are 1) the identification of a distributed control architecture, allowing the avoidance of single points of failure, 2) the management of both recoverable and non-recoverable faults, and 3) the definition of an overall reliable multi-FPGA system.
Theclinae of Rondônia, Brazil: Arcas , with descriptions of three new species (Lepidoptera: Lycaenidae). (1995)

Three new species of Areas are distinguished among samples of the genus from the lowland tropical rainforest in the western Amazon drainage of central Rondonia, Brazil: Areas magnifica n. sp ., Areas viriditas n. sp ., and Areas marginata n. sp. Morphological distinctions of the genitalia corroborate superficial differences noted in wing pattern and androconial brands. Samples of other Eumaeini genera from this study area contain numerous examples of new species occurring in sympatry and/or synchrony with more well-known taxa. These afford an opportunity for study of ecological and biological differences separating these taxa.
A class of randomized strategies for low-cost comparison of file copies (1991)

A class of algorithms that use randomized signatures to compare remotely located file copies is presented. A simple technique that sends on the order of 4/sup f/log(n) bits, where f is the number of differing pages that are to be diagnosed and n is the number of pages in the file, is described. A method to improve the bound in the number of bits sent, making them grow with f as flog(f) and with n as log(n)log(log(n)), and a class of algorithms in which the number of signatures grows with f as fr/sup f/, where r can be made to approach 1, are also presented. A comparison of these techniques is discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
GeoScale: Providing Geo-Elasticity in Distributed Clouds (2016)

Distributed cloud platforms are well suited for serving a geographically diverse user base. However traditional cloud provisioning mechanisms that make local scaling decisions are not well suited for temporal and spatial workload fluctuations seen by modern web applications. In this paper, we argue the need of geo-elasticity and present GeoScale, a system to provide geo-elasticity in distributed clouds. We describe GeoScale's model-driven proactive provisioning approach and conduct an initial evaluation of GeoScale on Amazon's distributed EC2 cloud. Our results show up to 31% improvement in the 95th percentile response time when compared to traditional elasticity techniques.
OFDM and TDM based sensing method for large projected mutual-capacitance touch screens (2016)

This paper presents a new technique for reading out projected mutual capacitance touch screen panels. It models touch screen panel as a communication system. Orthogonal frequency division multiplexing (OFDM) is used along with time division multiplexing (TDM) to read out all channels of touch screen panels. Different carrier frequencies are applied to touch screen panel concurrently using OFDM, while the sensing lines are sensed sequentially using TDM. The proposed technique ensures a high frame scan rate by using simultaneous driving signals, and it provides high signal to noise ratio (SNR) by avoiding frequency band with high noise power. Simulation results demonstrate a SNR improvement of 8.2 dB by selecting adequate carrier frequencies.
Mechanisms of melanogenesis inhibition by 2,5-dimethyl-4-hydroxy-3(2H)-furanone (2007)

Our study shows that DMHF inhibits alpha-MSH-induced melanogenesis by suppressing CREB phosphorylation, which is induced by protein kinase A, and suggests that DMHF may be an effective inhibitor of hyperpigmentation.
Business @ the Speed of Thought: Succeeding in the Digital Economy (2000)

From the Publisher:
The CEO and chairman of Microsoft shows how technology has become key factor in effectively operating businesses; discusses how the creation of a worldclass digital nervous system will provide constant learning and promote success; and provides indepth examples of companies that used technology to turn failure into victory.
Improved sorbent for the sorption-enhanced water-gas shift process (2011)

For the sorption-enhanced water-gas shift (SEWGS) process, a new sorbent material has been developed. The sorbent is a potassium-carbonate promoted hydrotalcite-based material. The material has been tested under realistic process conditions in an experimental rig of 2 m length. The cyclic capacity of the material is 27% higher than the cyclic capacity of the reference sorbent, which was used in CACHET, a previous R&D project. Moreover, 36% less steam is required for its regeneration. The sorbent pellets also have a 65% higher crush strength than the reference sorbent. Contrary to the reference material, the novel material does not form notable amounts of MgCO3 under relevant operating conditions. Due to the absence of this slow CO2 uptake process, the sorbent remains mechanically stable, the cyclic steady state is reached rapidly, CO2 slip in the product gas is reduced, and steam requirements are lowered. It is demonstrated that the sorbent remains mechanically stable during operation of at least 1200 adsorption–desorption cycles. With this new, higher density material, carbon capture levels exceeding 95% can be obtained more efficiently and vessels will be smaller.
Nonsteroidal progesterone receptor ligands. 1. 3-Aryl-1-benzoyl-1,4,5,6- tetrahydropyridazines. (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNonsteroidal progesterone receptor ligands. 1. 3-Aryl-1-benzoyl-1,4,5,6- tetrahydropyridazines.Donald W. Combs, Kimberly Reese, and Audrey PhillipsCite this: J. Med. Chem. 1995, 38, 25, 4878–4879Publication Date (Print):December 1, 1995Publication History Published online1 May 2002Published inissue 1 December 1995https://pubs.acs.org/doi/10.1021/jm00025a003https://doi.org/10.1021/jm00025a003research-articleACS PublicationsRequest reuse permissionsArticle Views314Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Jaynes' principle and maximum entropy spectral estimation (1984)

This paper makes use of Jaynes' principle to include prior information into a maximum entropy spectral estimate. Such information is often available, but is not included in the usual maximum entropy method. The paper develops an algorithm which is particularly simple to implement for equispaced correlation lags. A numerical example demonstrates the effectiveness of the technique, and its superiority to the usual maximum entropy method.
Speech quality and stable gain trade-offs in adaptive feedback cancellation for hearing aids (2017)

This paper addresses trade-offs in adaptive feedback cancellation (AFC) for hearing aids. Aggressive AFC for improved added stable gain (ASG) reduces speech quality. In this paper, the hearing-aid speech quality index (HASQI) is used to investigate AFC performance before the system becomes unstable. It is demonstrated that for a desired speech quality, multiple AFC algorithms can be evaluated for their ASG and computational efficiency. An example is presented with HASQI = 0.8, baseline AFC, and two advanced approaches. For the advanced AFCs, ASG gains of 4 and 7 dB were obtained at additional computational complexity of 8% and 11%, respectively.
Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture. (1994)

In order to improve our understanding of the control of adipose tissue development in man by adipogenic and antiadipogenic factors we studied the effect of transforming growth factor beta (TGF beta) on the differentiation of human adipocyte precursor cells cultured in a serum-free medium. Addition of TGF beta at concentrations ranging from 5 to 100 pmol/l for 24 h at the beginning of the differentiation process resulted in a dose-dependent reduced expression of glycero-3-phosphate dehydrogenase (GPDH) activity. Continuous exposure of cells to TGF beta completely blocked differentiation even at a concentration of 5 pmol/l. Under these conditions cells were not able to accumulate lipid droplets. This inhibitory effect of TGF beta was not mediated by stimulation of cell proliferation. Exposure of newly developed fat cells to TGF beta was also associated with a significant suppression of GPDH activity. A 10-day incubation of cells with TGF beta reduced GPDH activity by more than 80% compared to controls. Despite this suppressive effect cells retained the typical fat cell-like morphology. In conclusion, these data clearly suggest that TGF beta exerts an inhibitory action on human adipose tissue development and reduces the activity of a lipogenic key enzyme in newly formed fat cells.
IMAGE ZOOMING BY WAVELETS (2000)

Enlargement and reduction of images are often required in image processing. Popular methods for re-sizing are standard interpolation methods. Recently, wavelets and fractal-based methods are developed for re-sizing. In this paper, wavelet zooming algorithm based on pyramid algorithm for wavelet transformation is explained. Also performance analysis of wavelet-based zooming method is investigated. We find that wavelet zooming with enhanced coefficients gives better visual quality. The objective error analysis also agrees with this. Wavelet zooming has also been performed block-wise. A significant drawback of the method is that the scaling factor should be power of 2.
Incremental certification and Integrated Modular Avionics (2009)

When designing Integrated Modular Avionics (IMA) systems, the traditional design life cycle must be adapted and rearranged to allow multiple vendors to contribute not only to the systems design, but also to the safety case for the system. Simply using guidelines from the DO-178B and the ARINC 653 standards does not guarantee that one will be able to have multiple applications running at different safety criticality levels. One needs to be able to merge applications written by different vendors, reuse applications from previous projects, and integrate different safety requirements while constructing a safety case for the overall IMA system. This, of course, must be done within a constrained budget that includes potential costs associated with changing program requirements. In order to achieve these goals, the design life cycle must be constructed in a way that allows for configuration and build partitioning of these applications, in parallel with the IMA platform itself and the overall systems integration. This investigates how the ARINC 653 standard can be used to provide this application and safety criticality level independence using guidelines from DO-178 and DO-297. It explores the use of qualified XML-based configuration tools, the emerging ARINC 653 Supplement 3 XML Schema design and shows the importance of configuration and build partitioning.
Biology of the human malignant lymphomas I. Establishment in continuous cell culture and heterotransplantation of diffuse histiocytic lymphomas (1974)

With the aid of a new methodology of tissue culture which permits rapid screening of nutrient requirements, the tumor cells from pleural or peritoneal effusions of three patients with diffuse histiocytic lymphomas have been established in continuous culture in vitro and designated as the SU-DHL-I, SU-DHL-2, and SU-DHL-3 cell lines, respectively. All three cell lines required a 10% supplement of human pleural effusion fluid or human serum for continuous growth. Morphologically, they closely resembled the tumor cells of the original patients as seen in lymph node biopsies or in pleural or peritoneal effusion fluids. Histochemical studies revealed positive reactions for nonspecific esterase, acid phosphatase, and methyl green-pyronin in both the original tumor cells and the histiocytic lymphoma cell lines. Cytoplasmic vacuoles, which were particularly conspicuous in the-SU-DHL-I cells, were shown to contain lipid. In contrast, a lymphoblastoid cell line, SU-LB-I, was negative for nonspecific esterase, acid phosphatase, and lipid. The histiocytic lymphoma cell lines were more rigorously distinguishable from lymphoblastoid cell lines by their negative EBNA test reactions for the presence of the Epstein-Barr virus (EBV) genome and by their lack of surface immunoglobulin staining reactions characteristic of B-lymphocytes. Cytogenetic studies demonstrated that early culture passages of the histiocytic lymphoma cell lines were aneuploid. These cells were also successfully heterotransplanted in the brains of congenitally athymic (“nude”) mice, providing further evidence of their neoplastic character. These histiocytic lymphoma cell lines provide an important new resource for studies of this group of highly malignant human lymphomas.
Modular Self-Reconfigurable Robot Systems (2007)

The field of modular self-reconfigurable robotic systems addresses the design, fabrication, motion planning, and control of autonomous kinematic machines with variable morphology. Modular self-reconfigurable systems have the promise of making significant technological advances to the field of robotics in general. Their promise of high versatility, high value, and high robustness may lead to a radical change in automation. Currently, a number of researchers have been addressing many of the challenges. While some progress has been made, it is clear that many challenges still exist. By illustrating several of the outstanding issues as grand challenges that have been collaboratively written by a large number of researchers in this field, this article has shown several of the key directions for the future of this growing field
Inhibition of photosynthesis by heat stress: the activation state of Rubisco as a limiting factor in photosynthesis (2004)

Although the catalytic activity of Rubisco increases with temperature, the low affinity of the enzyme for CO 2 and its dual nature as an oxygenase limit the possible increase in net photosynthesis with temperature. For cotton, comparisons of measured rates of net photosynthesis with predicted rates that take into account limitations imposed by the kinetic properties of Rubisco indicate that direct inhibition of photosynthesis occurs at temperatures higher than about 30°C. Inhibition of photosynthesis by moderate heat stress (i.e. 30–42°C) is generally attributed to reduced rates of RuBP regeneration caused by disruption of electron transport activity, and specifically inactivation of the oxygen evolving enzymes of photosystem II. However, measurements of chlorophyll fluorescence and metabolite levels at air‐levels of CO 2 indicate that electron transport activity is not limiting at temperatures that inhibit CO 2 fixation. Instead, recent evidence shows that inhibition of net photosynthesis correlates with a decrease in the activation state of Rubisco in both C 3 and C 4 plants and that this decrease in the amount of active Rubisco can fully account for the temperature response of net photosynthesis. Biochemically, the decrease in Rubisco activation can be attributed to: (1) more rapid de‐activation of Rubisco caused by a faster rate of dead‐end product formation; and (2) slower re‐activation of Rubisco by activase. The net result is that as temperature increases activase becomes less effective in keeping Rubisco catalytically competent. In this opinionated review, we discuss how these processes limit photosynthetic performance under moderate heat stress.
SPATIAL RELATIONSHIPS IN EARLY SIGNALING EVENTS OF FLOW-MEDIATED ENDOTHELIAL MECHANOTRANSDUCTION (1997)

Blood flow interactions with the vascular endothelium represent a specialized example of mechanical regulation of cell function that has important physiological and pathological cardiovascular consequences. The endothelial monolayer in vivo acts as a signal transduction interface for forces associated with flowing blood (hemodynamic forces) in the acute regulation of artery tone and chronic structural remodeling of arteries, including the pathology of atherosclerosis. Mechanisms related to spatial relationships at the cell surfaces and throughout the cell that influence flow-mediated endothelial mechanotransduction are discussed. In particular, flow-mediated ion channel activation and cytoskeletal dynamics are considered in relation to topographic analyses of the luminal and abluminal surfaces of living endothelial cells.
Highly Persistent and Effective Prime/Boost Regimens against Tuberculosis That Use a Multivalent Modified Vaccine Virus Ankara-Based Tuberculosis Vaccine with Interleukin-15 as a Molecular Adjuvant (2010)

Novel immunization strategies are needed to enhance the global control of tuberculosis (TB). In this study, we assessed the immunizing activity of a recombinant modified vaccinia Ankara (MVA) construct (MVA/IL-15/5Mtb) which overexpresses five Mycobacterium tuberculosis antigens (antigen 85A, antigen 85B, ESAT6, HSP60, and Mtb39), as well as the molecular adjuvant interleukin-15 (IL-15). Homologous prime/boost studies showed that the MVA/IL-15/5Mtb vaccine induced moderate but highly persistent protective immune responses for at least 16 months after the initial vaccination and that the interval between the prime and boost did not significantly alter vaccine-induced antituberculosis protective immunity. At 16 months, when the Mycobacterium bovis BCG and MVA/IL-15/5Mtb vaccine-induced protection was essentially equivalent, the protective responses after a tuberculous challenge were associated with elevated levels of gamma interferon (IFN-gamma), IL-17F, Cxcl9, and Cxcl10. To amplify the immunizing potential of the MVA/IL-15/5Mtb vaccine, a heterologous prime/boost regimen was tested using an ESAT6-antigen 85B (E6-85) fusion protein formulated in dimethyldiotacylammonium bromide/monophosphoryl lipid A (DDA/MPL) adjuvant as the priming vaccine and the MVA/IL-15/5Mtb recombinant virus as the boosting agent. When MVA/IL-15/5Mtb vaccine boosting was done at 2 or 6 months following the final fusion protein injections, the prime/boost regimen evoked protective responses against an aerogenic M. tuberculosis challenge which was equivalent to that induced by BCG immunization. Long-term memory after immunization with the E6-85-MVA/IL-15/5Mtb combination regimen was associated with the induction of monofunctional CD4 and CD8 IFN-gamma-producing T cells and multifunctional CD4 and CD8 T cells expressing IFN-gamma/tumor necrosis factor alpha (TNF-alpha), TNF-alpha/IL-2, and IFN-gamma/TNF-alpha/IL-2. In contrast, BCG-induced protection was characterized by fewer CD4 and CD8 monofunctional T cells expressing IFN-gamma and only IFN-gamma/TNF-alpha and IFN-gamma/TNF-alpha/IL-2 expressing multifunctional T (MFT) cells. Taken together, these results suggest that a heterologous prime/boost protocol using an MVA-based tuberculosis vaccines to boost after priming with TB protein/adjuvant preparations should be considered when designing long-lived TB immunization strategies.