gebhart/patrepeval huggingface dataset:
Reading Gary Snyder (1999)

Reading Gary Snyder Get access John Lane John Lane Search for other works by this author on: Oxford Academic Google Scholar ISLE: Interdisciplinary Studies in Literature and Environment, Volume 6, Issue 1, Winter 1999, Page 137, https://doi.org/10.1093/isle/6.1.137 Published: 01 January 1999
Cloning of fas cDNA from human liver cDNA library (2000)

To get the Human Fas cDNA and investigate the function of Fas (CD95), the higt titer dig-Fas cDNA probes and phage plaques hybridization technique were used to get a few Fas cDNA clones, from human liver cDNA library.
Membrane-controlled transdermal therapeutic system containing clonazepam and anticonvulsant activity after its application. (1989)

A trial transdermal dosage form designed to sustain a suitable plasma concentration of clonazepam (CZP) was produced using a porous membrane (Hipore 2100 or 4050) and applied to rabbits and rats for pharmacokinetic and pharmacodynamic evaluations. The release rate constants for the drug through the porous membranes were significantly smaller than that without any membrane. The transdermal system (Hipore 4050 system, ointment 0.25 g, 2.25 cm2) provided a well sustained plasma concentration of CZP and the therapeutic plasma concentration range was maintained for about 26 h. When the Hipore 4050 system with an increased amount of ointment and enlarged absorption area (0.5 g, 4.0 cm2) was applied, the therapeutic range was sustained for about 40 h, and slightly higher plasma levels over the whole application period and much higher bioavailability (37%) were obtained compared with those after the 2.25 cm2-Hipore 4050 system. The transdermal system exerted an excellent anticonvulsant activity in rats, with the best (3+ or 4+) protective score. The plasma concentrations of CZP when the activity was estimated were in the therapeutic range. Thus, the transdermal system has the potential to be an efficient drug delivery system.
Novel Multi-way Broadband Differential Phase Shifter With Uniform Reference Line Using Coupled Line Structure (2015)

Conventional passive differential phase shifters (DPSs) usually require different reference lines to realize varied differential phase shifts, this results in both complex structure and bulky size for multi-way poly-phase applications. To resolve the problem, a DPS configuration with uniform reference line is proposed. It is constructed using basic coupled lines with simplicity in both design and fabrication procedures. The delay lines of the phase shifter have a similar structure and maintain desired constant phase shift compared with the uniform reference line over a wide bandwidth. To verify the proposed configuration, a four-way DPS which is comprised of 3 delay lines and a reference line, is designed, fabricated and measured. The delay lines provide the corresponding constant phase shifts (45 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> , 90 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> , 135 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> compared to the reference line. Over a bandwidth of 45%, excellent performance is achieved with small insertion loss and phase deviation.
Stroboscopic technique for measurement of fluorescence lifetimes of bacteria and biological interferents (2006)

Time-resolved fluorescence was measured for 25 biological species of vegetative bacteria, spores, fungi and pollens using stroboscopic technique and UV LEDs (280 and 340 nm) as a source of excitation. For all the examined species, the fluorescence lifetime was described by double exponential kinetics. With excitation at 280 nm, the decay time of the slow component varies from 2.0 to 4.6 ns. The fast component varies from 0.4 to 1.1 ns and its relative amplitude is greater than measured in tryptophan solution, which is a result of strong fluorescence quenching. For excitation at 340 nm, the lifetimes of fluorescence components are 3-9 ns and 0.4-1.9 ns, respectively. Higher differences in decay times are observed for other groups, especially pollens, that is connected with higher number of fluorophores in this spectral range. In general, lifetimes and relative fractional contributions of components are various for particular biological species, however, they are not specific for one group, what causes difficulties in BWA classification with time-resolved fluorescence method. Evaluation of the decay curves using PCA method shows low similarity of species in groups of living bacteria and spores and strong influence of interferents is observed.
Surveillance of pacemaker patients by an automatic pacemaker function analyzer. (1977)

An external, simply operated, fail-safe, automatic pacemaker function analyzer (PFA) has been designed for routine examination of ambulatory patients in local medical clinics and for continual surveillance of hospitalized patients in cardiology units. The instrument provides a comprehensive test of the pacing system, including the battery, pulse generator, and electrodes (leads), during varying heart activity. In the recorded ECG from 92 pacemaker patients, the PFA recognized all but 0.29% of the QRS complexes and 0.21% of the pacing artifacts; no signals were incorrectly attributed to the QRS complex. With the PFA, 1171 pacemaker tests were performed on these patients. In all cases, the PFA judged the performance of the tested pacemakers in accordance with the predetermined criteria. The PFA can be integrated into a pacemaker-patient surveillance system within a general-purpose cardiac care unit.
Oral fingolimod (FTY720) in multiple sclerosis (2009)

Once-daily oral treatment with FTY720, 1.25 or 5.0 mg, for up to 2 years, was well tolerated and was associated with low relapse rates and lesion activity.
The Physical and Genetic Framework of the Maize B73 Genome (2009)

Maize is a major cereal crop and an important model system for basic biological research. Knowledge gained from maize research can also be used to genetically improve its grass relatives such as sorghum, wheat, and rice. The primary objective of the Maize Genome Sequencing Consortium (MGSC) was to generate a reference genome sequence that was integrated with both the physical and genetic maps. Using a previously published integrated genetic and physical map, combined with in-coming maize genomic sequence, new sequence-based genetic markers, and an optical map, we dynamically picked a minimum tiling path (MTP) of 16,910 bacterial artificial chromosome (BAC) and fosmid clones that were used by the MGSC to sequence the maize genome. The final MTP resulted in a significantly improved physical map that reduced the number of contigs from 721 to 435, incorporated a total of 8,315 mapped markers, and ordered and oriented the majority of FPC contigs. The new integrated physical and genetic map covered 2,120 Mb (93%) of the 2,300-Mb genome, of which 405 contigs were anchored to the genetic map, totaling 2,103.4 Mb (99.2% of the 2,120 Mb physical map). More importantly, 336 contigs, comprising 94.0% of the physical map ( approximately 1,993 Mb), were ordered and oriented. Finally we used all available physical, sequence, genetic, and optical data to generate a golden path (AGP) of chromosome-based pseudomolecules, herein referred to as the B73 Reference Genome Sequence version 1 (B73 RefGen_v1).
<title>Recognition of moving vehicles using directional-temporal plane transform</title> (1992)

Traffic flow measurement systems, which recognize vehicles and measure traffic parameters by image processing, are researched. We propose a new recognition method for moving vehicles using directional-temporal plane transform (DTT) for the system. DTT is a transformation from spatiotemporal data to 2-D data onto a directional-temporal plane. The transformation is done by projecting feature data of vehicles to a directional axis which is roughly parallel to the moving loci, and by placing the projected data stream side by side in temporal order. We also show an effective extraction algorithm of vehicles from the 2-D data obtained by DTT. Experimental results using real images demonstrate the effectiveness of this method.
A High Performance and Cost Effective Molded Array Package Substrate (2010)

Ceramic engineer and manufacturing executive, Philip E. Rogren will explain why molded array packages such as QFNs promise significant cost advantages compared to competitive packaging techniques. He will also describe why there are significant limitations for array packaging techniques based on lead frames. Audiences will learn about the feature of lead frame based packages that is responsible for virtually all of these limitations: Every package terminal and die paddle is a portion of the continuous metal structure that is the lead frame. Every terminal and die paddle is connected to, and held in proper position by, otherwise useless metal projections extending out of the package site to supporting portions of the lead frame. This planer, unitary structure presents limitations in the design of packages, limiting lead counts to around 70 leads and impacting performance because of increased lead to lead parasitic. The structure also adds process steps and cost to the assembly operation. In this presentation Rogren will describe a novel MAP substrate that features print formed, discrete terminal structures and die paddles arrayed on a sacrificial steel substrate. This structure eliminates the disadvantages of the interconnected lead frame based technology. In addition, this manufacturing process substantially reduces the pollution-causing process steps and it eliminates non-recyclable waste.
A particle filter for track-before-detect (2001)

A Bayesian track-before-detect particle filter is proposed. The filter provides a sample based approximation to the distribution of the target state directly from pixel array data. The filter also provides a measure of the probability that a target is present.
Differential allograft gene expression in acute cellular rejection and recurrence of hepatitis C after liver transplantation (2002)

Treatment of acute cellular rejection (ACR) is associated with increased viral load, more severe histologic recurrence, and diminished patient and graft survival after liver transplantation for hepatitis C virus (HCV). Recurrence of HCV may be difficult to distinguish histologically from ACR. Because the immunologic mechanisms of ACR and HCV recurrence are likely to differ, we hypothesized that ACR is associated with the expression of a specific subset of immune activation genes that may serve as a diagnostic indicator of ACR and provide mechanistic insight into the pathophysiology of ACR and recurrence of HCV. The goal of the study was to study intragraft gene expression patterns in ACR and during recurrence of HCV in HCV-infected recipients. High-density microarrays were used to determine relative intragraft gene expression in two groups of HCV-infected liver transplant recipients: four with steroid responsive ACR by Banff criteria and four age- and gender-matched HCV-infected recipients with similar necroinflammatory activity but without histological criteria for rejection (no cholangitis or endotheliitis). Immunosuppression was similar in both groups. Other etiologies of graft dysfunction were excluded by ultrasound, cholangiography, and cultures. High-quality total RNA was extracted from snap frozen liver biopsies, reverse transcribed, labeled with biotin, and fragmented according to established protocol. Twenty-five genes were relatively overexpressed, and 15 were relatively underexpressed by > or = twofold in the ACR when compared with the HCV group. ACR was most notably associated with the relative overexpression of genes associated with major histocompatibility complex I and II, insulin-like growth factor-1 expression, apoptosis induction, and T-cell activation. In HCV-infected liver transplant recipients, ACR is associated with an intragraft gene expression profile that is distinct from that seen during recurrence of HCV. These experiments provide evidence that alloimmunity, as indicated by expression of T-cell activation and apoptosis-inducing genes, is less important in recurrence of HCV than in ACR. Further studies are required to determine whether gene expression profiles, either intragraft or in serum, can be used for the diagnosis and differentiation of ACR from recurrence of HCV.
The PEN1 Syntaxin Defines a Novel Cellular Compartment upon Fungal Attack and Is Required for the Timely Assembly of Papillae (2004)

Attack by the host powdery mildew Erysiphe cichoracearum usually results in successful penetration and rapid proliferation of the fungus on Arabidopsis. By contrast, the nonhost barley powdery mildew Blumeria graminis f. sp. hordei (Bgh) typically fails to penetrate Arabidopsis epidermal cells. In both instances the plant secretes cell wall appositions or papillae beneath the penetration peg of the fungus. Genetic screens for mutations that result in increased penetration of Bgh on Arabidopsis have recently identified the PEN1 syntaxin. Here we examine the role of PEN1 and of its closest homologue, SYP122, identified as a syntaxin whose expression is responsive to infection. pen1 syp122 double mutants are both dwarfed and necrotic, suggesting that the two syntaxins have overlapping functions. Although syp122-1 and the cell wall mur mutants have considerably more pronounced primary cell wall defects than pen1 mutants, these have relatively subtle or no effects on penetration resistance. Upon fungal attack, PEN1 appears to be actively recruited to papillae, and there is a 2-h delay in papillae formation in the pen1-1 mutant. We conclude that SYP122 may have a general function in secretion, including a role in cell wall deposition. By contrast, PEN1 appears to have a basal function in secretion and a specialized defense-related function, being required for the polarized secretion events that give rise to papilla formation.
GMR: An Attractive Resistance (1997)

An Attractive ResistanceMagnetoresistance was first discovered by Lord Kelvin.But he didn't have the technology to exploit it.Today, 141 years later, the effect, its clever younger brother giant magnetoresistance and pioneering studies of magnetic thin-film structures could soon enable very high density magnetic data storage and computer memory, by IBM science
Studies on the inorganic and crystal chemistry of some transition metal oxides. (1956)

No description available
A novel high-speed interface circuit saving wiring equipment (1978)

A high-speed integrated interface circuit is described, which is capable of transmitting and receiving full duplex digital signals on a twisted pair line. Thus two independent messages may be transmitted on one line at the same time. A push-pull transmitter and a differential amplifier as receiver provide a common-mode rejection of more than 1 V in either the positive or negative direction. Output signals and input threshold are compatible with ECL F100K. Compared to conventional interface transceivers this approach has the following advantages: (1) the needed number of lines and connectors is halved; (2) only one type of circuit is necessary, because both transmitter and receiver are housed in one package; (3) the reduced number of line pins leaves space for more transceiver circuits in one package.
Calculating lactate anaerobic thresholds in sports involving different endurance preparation (2013)

The aim of this study was to establish the degree of similarity of exercise intensity values at the anaerobic threshold (AT) provided by five methods of lactate curve analysis, i.e., LTAT, LTloglog, 1 mmol AT, 4 mmol AT, and D-max. The pattern of similarities and differences was sought in athletes with varying levels of experience and sports skills, representing two disciplines with different prevailing types of power output during competition: on-road cycling (aerobic metabolism) and ice-hockey (anaerobic metabolism). All groups of athletes tested [Group 1: on-road cyclists (n = 19) at international sporting level (participants of the Olympic Games and World Championships); Group 2: on-road cyclists (n = 20) at national sporting level; Group 3: ice-hockey players (n = 24) at international sporting level (Polish National Team); and Group 4: ice-hockey players (n = 22) at international sporting level (Polish National Team U-20)] performed an incremental exercise. The greatest power values at the anaerobic threshold (PAT) were provided by the LTAT (221.93 ± 34.5 W) and 4 mmol AT (226.38 ± 32.33 W) methods, whereas the lowest were provided by the LTloglog (190.71 ± 25.92 W) method. The PAT produced by the LTloglog method was statistically significantly lower (p ≤ 0.001) than the values provided by LTAT, 4 mmol AT, and Dmax. The PAT levels were found to be statistically significantly different for power values determined using the 4 mmol AT and those produced by the 1 mmol AT (p ≤ 0.001) and D-max (p ≤ 0.01) methods. As shown by the analyses, PAT values vary in the international-level on-road cyclists depending on the method of lactate curve analysis applied.
Microlasers for photonic switching and interconnection (1990)

Vertical-cavity, surface-emitting lasers have great potential owing to their inherent two-dimensional geometry and very small gain nedium volumes which are essential to low threshold currents. Possible applications are optical switching/computing, photonic interconnection, high/low power laser sources, image processing, optical neural networks, etc. Driven by these high promises, there have been numerous reports on vertical cavity surface emitting laser diodes using InGaAs/GaAs/A1As, GaAs/AlGaAs structures16. In this paper, we report characteristics of discrete InGaAs microlasers and monolithic two-dimensional arrays of microlasers. The advantages of optics for communications of data over distances longer than nearby gates have been argued previously7. We proposed and demonstrated a photonic interconnect scheme using microlasers with planar optics which will be robust, accurate, and easily alignable.
Tuning the Hyperdrone (2015)

The HyperDrone is an instrument that generates acoustic waves taken from the data generated by seismic sensors across the surface of the entire globe. The data here is supplied by the Atomic Weapons Establishment Blacknest, Reading UK, which is part of the Comprehensive Test Ban Treaty Organisation (CTBTO) which monitors the ground for nuclear-scale explosions. This data is now contributing to other systems, such as early warning earthquake and tsunami alerts data.The entire network acts as a 'hyper' object, that is, a form which is too large (in scale of space/time etc), or too small in scale (of visibility etc), to be perceived by humans without the use of scientific systems. Data is arranged to be played back to generate resonance - a hyper 'drone' through the radome panel itself. The panel has been developed to work with a resonating geometric ‘tensegrity’ structure which was designed and made from aluminium and steel by Rob Smith during his artist residency at Wysing, where the Hyper Drone is currently located.
Iridium-Catalyzed <i>anti</i>-Diastereo- and Enantioselective Carbonyl (Trimethylsilyl)allylation from the Alcohol or Aldehyde Oxidation Level (2010)

Using the ortho-cyclometalated pi-allyl iridium precatalyst (R)-I derived from [Ir(cod)Cl](2), 4-cyano-3-nitrobenzoic acid, (R)-SEGPHOS, and allyl acetate, enantioselective transfer hydrogenation of alpha-(trimethylsilyl)allyl acetate in the presence of aldehydes 2a-i mediated by 2-propanol delivers products of (trimethylsilyl)allylation 4a-i in good isolated yields and with exceptional levels of anti-diastereoselectivity and enantioselectivity (90-99% ee). In the absence of 2-propanol, but under otherwise identical reaction conditions, carbonyl (trimethylsilyl)allylation is achieved directly from the alcohol oxidation level to furnish an equivalent set of adducts 4a-i with roughly equivalent isolated yields and stereoselectivities. To evaluate the synthetic utility of the reaction products 4a-i, adduct 4g was converted to the 1,4-ene-diol 5g via dioxirane-mediated oxidative desilylation with allylic transposition, the allylic alcohol 6g via protodesilylation with allylic transposition, and the gamma-lactam 7g via chlorosulfonyl isocyanate-mediated cycloaddition.
1997/98 BUDGET: RURAL AND REMOTE HEALTH INITIATIVES AND OTHER PROGRAMS (1997)

ABSTRACT: This article provides an outline of the Commonwealth Governments 1997/98 Budget intitiatives and existing rural and remote health support programs.
An interactive and immersive human–computer interface for rapid composite part production design (2017)

This article addresses the need for better retention and exploitation of tacit knowledge for intelligent computer-aided design. It presents an automated design framework for the development of individual part forming tools for a composite stiffener incorporating parametrically developed design geometries. This work develops existing principles in knowledge-based engineering and parametric modelling beyond product design in the manufacturing planning domain. Outcomes demonstrate chronological benefits of automated process design methods as well as learning enhancements as the tacit knowledge data set can now include an applied element through an auto-generated virtual build environment. A virtual environment presenting a design concept to the planner for interactive assembly assessment was generated in twenty seconds and enabled the completion of virtual builds in support of the development of an optimal forming tool arrangement. This principle enables the addition of an experiential tacit knowledge feedback loop to further improve assembly planning for design concepts as they evolve. Challenges still exist in determining the level of reality required to provide an effective learning environment in the virtual world. Full representation of physical phenomena such as gravity, part clashes and the representation of standard build functions require further work to represent real physical phenomena robustly.
Lysogenic pneumococci and their bacteriophages (1979)

About half of pneumococci recovered from pediatric patients and one-third of isolates from adult patients yielded bacteriophages active against one or more of four noncapsulated indicator strains of pneumococcus. Strains of capsular types most frequently causing pediatric infections were associated with lysogeny. Classical restriction-modification phenomena have been demonstrated in vivo with some of the temperate phages, and correlation of restriction with the presence of one or the other of the two known pneumococcal restriction endonucleases has been established. The temperate phages differ serologically and in several other characteristics from virulent pneumococcal phages previously described. All pneumococcal phages so far studied can be classified into a minimum of three serological groups.
Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations (2014)

Advances in computer hardware, software and algorithms have now made it possible to run atomistically detailed, physics-based molecular dynamics simulations of sufficient length to observe multiple instances of protein folding and unfolding within a single equilibrium trajectory. Although such studies have already begun to provide new insights into the process of protein folding, realizing the full potential of this approach will depend not only on simulation speed, but on the accuracy of the physical models ('force fields') on which such simulations are based. While experimental data are not available for comparison with all of the salient characteristics observable in long protein-folding simulations, we examine here the extent to which current force fields reproduce (and fail to reproduce) certain relevant properties for which such comparisons are possible.