gebhart/patrepeval huggingface dataset:
Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular classifiers of ovarian cancer (2006)

In order to elucidate the biological variance between normal ovarian surface epithelial (NOSE) and epithelial ovarian cancer (EOC) cells, and to build a molecular classifier to discover new markers distinguishing these cells, we analysed gene expression patterns of 65 primary cultures of these tissues by oligonucleotide microarray. Unsupervised clustering highlights three subgroups of tumours: low malignant potential tumours, invasive solid tumours and tumour cells derived from ascites. We selected 18 genes with expression profiles that enable the distinction of NOSE from these three groups of EOC with 92% accuracy. Validation using an independent published data set derived from tissues or primary cultures confirmed a high accuracy (87-96%). The distinctive expression pattern of a subset of genes was validated by quantitative reverse transcription-PCR. An ovarian-specific tissue array representing tissues from NOSE and EOC samples of various subtypes and grades was used to further assess the protein expression patterns of two differentially expressed genes (Msln and BMP-2) by immunohistochemistry. This study highlights the relevance of using primary cultures of epithelial ovarian cells as a model system for gene profiling studies and demonstrates that the statistical analysis of gene expression profiling is a useful approach for selecting novel molecular tumour markers.
Ablation of MEK Kinase 1 Suppresses Intimal Hyperplasia by Impairing Smooth Muscle Cell Migration and Urokinase Plasminogen Activator Expression in a Mouse Blood-Flow Cessation Model (2005)

MEKK1 is implicated in vascular remodeling after blood-flow cessation by regulating the migration and uPA expression of SMCs. MEKK1 is a potential target for drug development to prevent vascular remodeling.
Graft copolymerization by pre‐irradiation technique (1959)

Abstract Trapped free radicals are formed when polyethylene is irradiated with cobalt‐60 gamma rays in the absence of any reactive species‐oxygen, monomer, etc. The net free radical population formed increases with increasing total dose, decreasing temperature of irradiation, and increasing crystallinity of the polymer. Upon addition of a monomer to these vacuum‐irradiated films, the monomer will graft copolymerize. Graft coplymers produced by this technique are the most homogeneous, compared to those formed using other radiation‐induced techniques. If oxygen is present during the irradiation many of the free radicals formed are consumed in reaction with the oxygen to produce peroxides, hydroperoxides, and other oxygen‐containing groups. The ratio of trapped free radicals to those reacted with oxygen increases with increasing crystallinity of the polyethylene. When films irradiated in air are subsequently contacted with monomer, grafting occurs, even at room temperature, and increases in rate at higher tamperatures. It is believed that the initiation of grafting in these films is accomplished by trapped radicals and peroxide decomposition. The graft copolymers formed by this technique are not as homogeneous as those formed in the vacuum irradiation technique, but are far more homogeneous than those formed in either of the simultaneous irradiation‐grafting techniques.
Upper air pressure and density measurements from 90 to 220 kilometers with the Viking 7 rocket (1957)

The density and pressure of the atmosphere from 90 to 220 km above White Sands, New Mexico, were determined from the Viking 7 rocket flight on 7 August 1951 at 11:00 a.m. MST. A Philips ionization gage was used to measure pressure and pressure changes on the side of the nose cone of the rolling rocket. Measured pressure in the 90 to 105 km region were corrected for velocity ram and residual gas, and were approximately one-fourth of the Rocket Panel values. The derived pressure of 3×10−7 mm Hg at 220 km is twice the corresponding Rocket Panel value. Densities were measured from 120 to 185 km and at 220 km. The 220 km density value of 9×10−8 gm/m3 agrees with the Rocket Panel value. However, the density values at the lower altitudes are one-fourth to one-half those of the Rocket Panel. These lower density values in the 100 to 130 km region are in good agreement with values obtained from X-ray absorption experiments. Scale heights, (RT/Mg), derived from the density data above 140 km, are approximately a factor of two higher than Rocket Panel values.
The Absorption of Human Factor VIII Neutralizing Antibody by Factor VIII (1974)

S ummary . A new technique has been devised for measuring the amount of human factor VIII neutralizing antibody that is absorbed by factor VIII. The method has been applied to factor VIII from normal donors and to factor VIII‐like antigen from haemophilic persons. When the absorption was tested for in relative antibody excess it was found that most haemophilic samples absorbed some antibody but that generally the amount absorbed was less than normal. When a lower antibody concentration was used and most of the antibody present was absorbed by the normal factor VIII, then the haemophilic antigens could be divided into two types. Patients previously diagnosed as haemophilia A + (Denson et al , 1969) provide an antigen which absorbed the normal amount of antibody, while those previously diagnosed as haemophilia A — provided an antigen which did not absorb antibody.
<title>Epoxy-photopolymer composites: thick recording media for holographic data storage</title> (2001)

Archival data-storage based on holographic methods requires high performance recording materials. Here, we describe an epoxy-photopolymer composite material which is sensitive to visible light and can be fabricated as thick films. These materials are prepared by combining photopolymerizable vinyl monomers with a liquid epoxy resin and an amine hardener. As the epoxy cures at room temperature, a solid matrix is formed which surrounds the unreacted photopolymer. These vinyl monomers are subsequently photopolymerized during hologram recording. Typically the material consists of a low index matrix, composed of diethylenetriamine and 1,4- butanediol diglycidyl ether, and a high index photopolymer mixture of N-vinylcarbazole and N-vinyl-2-pyrrolidinone. Because the polymers can be prepared in thick formats, narrow angular bandwidth holograms with high diffraction efficiency can be recorded. A dynamic range up to 13 has been measured in these materials.
Evanescent-field coupling between a monomode fiber and a high-index medium of limited thickness (1985)

By applying a coupled-mode theory to the angle degenerate modes of a planar waveguide and to the single mode of a neighboring monomode fiber, we derive an integrodifferential system describing the transfer of light intensity from the fiber to the planar waveguide. By numerically solving this system, the transmission loss of the fiber is computed as a function of various parameters such as the planar-guide thickness, the planar index, and the remaining fiber-cladding thickness.
A cost model for selecting checkpoint positions in time warp parallel simulation (2001)

Recent papers have shown that the performance of Time Warp simulators can be improved by appropriately selecting the positions of checkpoints, instead of taking them on a periodic basis. In this paper, we present a checkpointing technique in which the selection of the positions of checkpoints is based on a checkpointing-recovery cost model. Given the current state S, the model determines the convenience of recording S as a checkpoint before the next event is executed. This is done by taking into account the position of the last taken checkpoint, the granularity (i.e., the execution time) of intermediate events, and using an estimate of the probability that S will have to be restored due to rollback in the future of the execution. A synthetic benchmark in different configurations is used for evaluating and comparing this approach to classical periodic techniques. As a testing environment we used a cluster of PCs connected through a Myrinet switch coupled with a fast communication layer specifically designed to exploit the potential of this type of switch. The obtained results point out that our solution allows faster execution and, in some cases, exhibits the additional advantage that less memory is required for recording state vectors. This possibly contributes to further performance improvements when memory is a critical resource for the specific application. A performance study for the case of a cellular phone system simulation is finally reported to demonstrate the effectiveness of this solution for a real world application.
Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers. (1990)

Propionate produced in the colon from the fermentation of alpha-amylase-resistant starch and non-starch polysaccharides, is cholesterol lowering and gluconeogenic in animal models. In humans, little is known about the effect of propionate on metabolism. In a double-blind, paired-comparison, placebo-controlled study, the diet of 10 healthy female volunteers, aged 20-22 yr, was supplemented for a period of 7 wk with 7.5 g sodium propionate daily in capsule form, while the diet of the 10 control group members was supplemented with dibasic calcium phosphate in identical capsules as placebo. Propionate supplementation did not lower total serum cholesterol (TC), but increased HDLC (9.5%) (p less than 0.05) and triglyceride levels (16.7%, p less than 0.02) and decreased fasting serum glucose and maximum insulin increments during glucose tolerance tests (p less than 0.05). The results suggest that the improvement in glucose tolerance and insulin sensitivity and the known beneficial effect of dietary fiber on HDL metabolism may in part be mediated through effects of propionate on hepatic carbohydrate metabolism.
Enchanted Drawings: The History of Animation (1989)

Chapters: Precursors and Experiments; The Silent Era, 1914-1928; The Disney Era, 1928-1941; The Studio Cartoon, 1929-1941; Animation Goes to War, 1941-1945; The Home Front: Animation, 1941-1945; Wabbit Twacks in the Sands of Time, 1946-1960; Disney: The Silver Age, 1946-1960; UPA and the Graphic Revolution, 1943-1959; On the Small Screen: The Television Years; The Captains and the Kings Depart, 1960-1994; Bibliography; Index
Oxydation von Cyclododecanon nach Baeyer und Villiger (1965)

Abstract Durch Oxydation von Cyclododecanon mit Peressigsäure wird Dodecanolid in einer Ausbeute von 50% erhalten.
The DMX™ process: An original solution for lowering the cost of post-combustion carbon capture (2011)

To make the deployment of carbon capture possible, it is highly needed to develop original solutions that induce low energy penalty and that are easy to operate. This paper aims at presenting the DMX™ process developed at IFP Energies nouvelles based on special solvents which are characterized by the formation of two immiscible phases for given temperature and CO2 loading conditions. The concept of demixtion is briefly described in terms of physico-chemical properties, its interest and all required steps for appropriate process development are discussed. The corresponding process is presented and a technico-economic analysis is given. It is shown than one can reach a reboiler duty as low as 2.1 GJ/t CO2 which is significantly lower than the 3.7 GJ/t CO2 of the 30wt.% MEA reference process. It is also discussed that the energy consumption at reboiler cannot be the only parameter to consider for comparison with other processes and some further information about the DMX™ process are given. Operational issues are particularly discussed. In that sense, the performances of the DMX-1TM solvent in terms of degradation and corrosion are shown. Similarly a particular focus is made on the liquid/liquid separation which is a key aspect of the DMX™ process.
Ventricular Pacing Induced Ventricular Tachycardia in Patients with Implantable Cardioverter Defibrillators (1995)

Appropriately timed noncompetitive ventricular pacing potentially may initiate ventricular tachycardia in patients prone to these arrhythmias. The combination of bradycardia pacing and stored electrograms in a currently available cardioverter defibrillator provides an opportunity to evaluate the occurrence of such pacing induced ventricular tachycardia. During a surveillance period of 18.7 +/- 11.4 months, stored electrograms documented 302 episodes of ventricular tachycardia in 77 patients. Five patients (6.5%) demonstrated 25 episodes (1-16 per patient) of ventricular tachycardia that were immediately preceded by an appropriately paced ventricular beat (8.3% of all episodes of ventricular tachycardia). All five patients had prior myocardial infarctions and a history of monomorphic ventricular tachycardia occurring both spontaneously and in response to programmed electrical stimulation. Antitachycardia pacing terminated pacing induced ventricular tachycardia in 22 episodes; in one episode antitachycardia pacing accelerated ventricular tachycardia. In two cases shock therapy was aborted for nonsustained ventricular tachycardia. We conclude that, in selected nonsustained ventricular tachycardia. We conclude that, in selected postinfarction patients with recurrent sustained monomorphic ventricular tachycardia treated with implantable cardioverter defibrillators, appropriately timed ventricular pacing may induce ventricular tachycardia.
The selection of native plants for use in the Montana landscape: selection criteria, aesthetic, cultural and environmental evaluation (2019)

During the past 15 years the landscape industry has experienced increased pressure to use native plants as ornamentals. Although a demand for natives in general exists there has been a relunctance on the part of the industry to offer native species because of the economic risks involved. An ornamental scorecard was developed as an evaluation tool for comparing native plant species with plant species currently available on the ornamental market. The scorecard evaluated 24 native Montana plant species and 20 exotic ornamentals commonly used in the landscape industry in Montana. The aesthetic scorecard rated six visual characteristics using color photographs. Scored were form/habit, flower, fruit, bark, leaf, and seasonal characteristics. The thirteen environmental factors evaluated by the environmental scorecard were transplantability, lifespan, propagation, maintenance/cleanliness, soil texture and pH, moisture regime adaptability (both drought and flood tolerance), exposure tolerances (temperature, light, and wind), insect resistance, and disease resistance. Species were scored by a panel of professional evaluators in the botany, horticulture, nursery and landscape design/architecture fields. These scores allow selection of native plant species with visual and/or functional qualities that are of equal or greater value than those exhibited by plants already available on the retail market, and thus exhibit competitive marketing potential.
The Influence of Aminoguanidine on Borohydride Reducible Collagen Crosslinks and Wound Strength (1991)

The mechanical strength of skin wounds as well as the deposition of hydroxyproline and KB3H4 reducible hydroxylysinonorleucine (HLNL) and dihydroxylysinonorleucine (DHLNL) cross-links in subcutaneously implanted cellulose sponges have been investigated in rats treated with aminoguanidine (AG) or beta-aminopropionitrile (BAPN). Treatment with AG (25 mg/kg BW/day) did not influence the mechanical strength of the wounds, the deposition of hydroxyproline or the pattern of reducible collagen cross-links, whereas AG (125 mg/kg BW/day) reduced the maximum load by 17%, but did not influence the deposition of hydroxyproline or reducible cross-linking pattern. Treatment with BAPN (333 mg/kg BW/day) reduced the strength of the wounds by 59%, the HLNL by 50% and the DHLNL 57%, whereas the deposition of hydroxyproline did not seem to be influenced by BAPN treatment. In conclusion, AG at moderate dosage does not seem to influence the formation of lysyl oxidase dependent reducible cross-links of collagen.
Group IV Analogs and High Pressure, High Temperature Synthesis of B<sub>2O</sub> (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGroup IV Analogs and High Pressure, High Temperature Synthesis of B2OH. Tracy Hall and Lane A. ComptonCite this: Inorg. Chem. 1965, 4, 8, 1213–1216Publication Date (Print):August 1, 1965Publication History Published online1 May 2002Published inissue 1 August 1965https://doi.org/10.1021/ic50030a027Request reuse permissionsArticle Views297Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (491 KB) Get e-Alertsclose Get e-Alerts
Turbulence-Assisted High-Throughput Liquid–Liquid Extraction in Microfluidics and Ni(OH)<sub>2</sub> Nanoparticles for Electrochemical Determination of Monoethylene Glycol Traces in Natural Gas Condensate (2018)

While monoethylene glycol (MEG) is an efficient alternative to prevent the generation of hydrates into the natural gas (NG) processing pipes, this specie also generates undesirable effects such as pipe corrosion, catalyst poisoning, quality loss of the fuel, and environment contamination. Thus, MEG is removed from the system in final stages of the NG processing and is regenerated for reuse, making mandatory its monitoring in both regenerated samples and fuels such as the NG condensate (NGC). Herein, we address a simple and fast method to determine MEG traces in NGC which was based on two stages: microfluidic liquid–liquid extraction (LLE) and electrochemical detection. High throughput (residence time of 0.05 s) and efficient LLEs were obtained in a single run by pumping the immiscible phases at harsh flow rates (up to 40 mL min–1) into a bulky chip (without interface) composed of bisphenol A (BSA)-based epoxy resin, which was prototyped using a clean-room-free and bondless approach. This unprecedented substrate in microfluidics showed resistance to elastic deformation and swelling in different organic media. The extraction was essential to allow the electrochemical determination of MEG, in which the aqueous acceptor phase from LLE was used as an electrolytic sample. Nickel disks modified with Ni(OH)2 nanoparticles provided a sensitive quantification of MEG, because of the high electrode surface area and catalytic activity of Ni(OH)2 for the irreversible oxidation of MEG. This electrode further requires a simple surface modification. We believe the method reported in this manuscript is a powerful alternative to monitor MEG in NGC samples by the industry.
30.3: Autostereoscopic Partial 2‐D/3‐D Switchable Display Using Liquid‐Crystal Gradient Index Lens (2010)

Abstract We developed 12‐inch 9‐view autostereoscopic partial 2‐D/3‐D switchable display using liquid crystal gradient index (GRIN) lens. We simulated optically by the stacked refraction‐index distribution model and optimized liquid crystal (LC) material and electrode structure. The prototype achieved wide viewing angle and good 3‐D image quality with mosaic color filter and vertical lens.
<title>Recent Developments In Infrared Acousto-Optic Tunable Filters</title> (1982)

We have designed and fabricated high performance acousto-optic tunable filters for operation in the infrared from 1.3 to 16 μm. These have been made from the crystal TL3AsSe3, in both collinear and non-collinear configurations. High efficiency has been achieved with low RF power density with interaction lengths up to 10 cm. This has become possible due to advances in the technology of large boule, oriented crystal growth.*
Shielded Passive Devices for Silicon-Based Monolithic Microwave and Millimeter-Wave Integrated Circuits (2006)

This paper introduces floating shields for on-chip transmission lines, inductors, and transformers implemented in production silicon CMOS or BiCMOS technologies. The shield minimizes losses without requiring an explicit on-chip ground connection. Experimental measurements demonstrate Q-factor ranging from 25 to 35 between 15 and 40 GHz for shielded coplanar waveguide fabricated on 10 /spl Omega//spl middot/cm silicon. This is more than a factor of 2 improvement over conventional on-chip transmission lines (e.g., microstrip, CPW). A floating-shielded, differentially driven 7.4-nH inductor demonstrates a peak Q of 32, which is 35% higher than an unshielded example. Similar results are realizable for on-chip transformers. Floating-shielded bond-pads with 15% less parasitic capacitance and over 60% higher shunt equivalent resistance compared to conventional shielded bondpads are also described. Implementation of floating shields is compatible with current and projected design constraints for production deep-submicron silicon technologies without process modifications. Application examples of floating-shielded passives implemented in a 0.18-/spl mu/m SiGe-BiCMOS are presented, including a 21-26-GHz power amplifier with 23-dBm output at 20% PAE (at 22 GHz), and a 17-GHz WLAN image-reject receiver MMIC which dissipates less than 65 mW from a 2-V supply.
On the Characterization and Optimization of On-Chip Cache Reliability against Soft Errors (2009)

Soft errors induced by energetic particle strikes in on-chip cache memories have become an increasing challenge in designing new generation reliable microprocessors. Previous efforts have exploited information redundancy via parity/ECC codings or cacheline duplication for information integrity in on-chip cache memories. Due to various performance, area/size, and energy constraints in various target systems, many existing unoptimized protection schemes may eventually prove significantly inadequate and ineffective. In this paper, we propose a new framework for conducting comprehensive studies and characterization on the reliability behavior of cache memories, in order to provide insight into cache vulnerability to soft errors as well as design guidance to architects for highly efficient reliable on-chip cache memory design. Our work is based on the development of new lifetime models for data and tag arrays residing in both the data and instruction caches. Those models facilitate the characterization of cache vulnerability of stored items at various lifetime phases. We then exemplify this design methodology by proposing reliability schemes targeting at specific vulnerable phases. Benchmarking is carried out to showcase the effectiveness of our approach.
Impact of QRS Morphology and Duration on Outcomes After Cardiac Resynchronization Therapy (2013)

URL: http://www.clinicaltrials.gov. Unique identifier: NCT00251251.