gebhart/patrepeval huggingface dataset:
BSMV as a Biotemplate for Palladium Nanomaterial Synthesis (2017)

The vast unexplored virus biodiversity makes the application of virus templates to nanomaterial synthesis especially promising. Here, a new biotemplate, Barley stripe mosaic virus (BSMV) was successfully used to synthesize organic-metal nanorods of similarly high quality to those produced with Tobacco mosaic virus (TMV). The mineralization behavior was characterized in terms of the reduction and adsorption of precursor and nanocrystal formation processes. The BSMV surface-mediated reduction of Pd<sup>(2+)</sup> proceeded via first-order kinetics in both Pd<sup>(2+)</sup> and BSMV. The adsorption equilibrium relationship of PdCl<sub>3</sub>H<sub>2</sub>O<sup>-</sup> on the BSMV surface was described by a multistep Langmuir isotherm suggesting alternative adsorbate-adsorbent interactions when compared to those on TMV. It was deduced that the first local isotherm is governed by electrostatically driven adsorption, which is then followed by sorption driven by covalent affinity of metal precursor molecules for amino acid residues. Furthermore, the total adsorption capacity of palladium species on BSMV is more than double of that on TMV. Finally, study of the BSMV-Pd particles by combining USAXS and SAXS enabled the characterization of all length scales in the synthesized nanomaterials. Results confirm the presence of core-shell cylindrical particles with 1-2 nm grains. The nanorods were uniform and monodisperse, with controllable diameters and therefore, of similar quality to those synthesized with TMV. Overall, BSMV has been confirmed as a viable alternate biotemplate with unique biomineralization behavior. With these results, the biotemplate toolbox has been expanded for the synthesis of new materials and comparative study of biomineralization processes.
Quantitative Cell Counts of the Bone Marrow and Blood and their Secular Variations in the Normal Adult Rat (1964)

Research Articles| March 17 2009 Quantitative Cell Counts of the Bone Marrow and Blood and their Secular Variations in the Normal Adult Rat Subject Area: Hematology , Oncology E.V. Hulse E.V. Hulse Medical Research Council, Radiobiological Research Unit, Harwell, Didcot, Berks Search for other works by this author on: This Site PubMed Google Scholar Acta Haematol (1964) 31 (1): 50–63. https://doi.org/10.1159/000209613 Article history Published Online: March 17 2009 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation E.V. Hulse; Quantitative Cell Counts of the Bone Marrow and Blood and their Secular Variations in the Normal Adult Rat. Acta Haematol 1 January 1964; 31 (1): 50–63. https://doi.org/10.1159/000209613 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsActa Haematologica Search Advanced Search This content is only available via PDF. 1964Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Article PDF first page preview Close Modal You do not currently have access to this content.
Degenerative Changes in the Organ of Corti and Lateral Cochlear Wall in Experimental Endolymphatic Hydrops and Human Meniere's Disease (1995)

The pathogenesis of sensorineural hearing loss in Menière's disease and experimental endolymphatic hydrops is not fully understood. At the light microscopic level, there is poor correlation between the histopathology and loss of sensitivity and speech discrimination. The results of electron microscopic investigation of histopathology and alterations in immunoreactivity in the organ of Corti and lateral cochlear wall in the hydropic guinea pig are presented. Loss of outer and inner hair cells and spiral ganglion cells, particularly in the apical turn was evident by light microscopy. By electron microscopy, further evidence of degeneration was detected in the cuticular plate of outer hair cells, neural endings of both inner and outer hair cells, myelinated dendritic fibers, spiral ganglion cells, and types I and II fibrocytes of the lateral cochlear wall. There was a marked decrease in immunoreactivity for a variety of enzymes, calcium binding proteins, structural proteins, and integral membrane proteins of gap junctions, particularly among type I and type II fibrocytes of the lateral cochlear wall. The evidence suggests that dysfunction and degeneration of hair cells, afferent neurons and fibrocytes of the lateral cochlear wall are involved in the pathogenesis of hearing loss in endolymphatic hydrops.
Experiences of Volunteers in Refugee Resettlement (2014)

Experiences of Volunteers in Refugee Resettlement ABSTRACT This paper examines the experiences of volunteers mentoring refugees resettled in the Atlanta area. Every year since 1980, the United States has resettled people who have been defined as refugees by the United Nations. Refugees come with few material resources and bring even greater ethnic variation into the country than other immigrants do. The federal government contracts with voluntary, non-governmental agencies to do the resettlement. Because of limited staff and funding, these agencies rely on volunteers to help in the resettlement process. This study describes the experiences of ten volunteers of varied age, race, and religion who have mentored refugee families. Most volunteers were first introduced to refugees either by a friend or by a church activity. They chose to mentor because of the teachings of their faith, a desire to impact the community, and empathy for the refugees. Volunteers developed friendships with the refugees while explaining American culture, guiding them to local facilities, and enjoying recreational activities. In spite of some difficulties, all the volunteers felt rewarded by love and friendship. All volunteers desired to repeat the mentoring experience and several sought even greater involvement in assisting refugees. In general the volunteers feel that refugees will successfully become Americans.
The Arrow-Debreu model: How math can hide a fatal conceptual error (2000)

I argue that math, like love, can cover a multitude of sins, and I use the neoclassical object of adoration, the Arrow-Debreu model, as the case in point. It is commonplace that the Arrow-Debreu (AD) model of general equilibrium does not describe the real world, but it is equally commonplace to accept it as representing the pure logic of the competitive capitalist economy in an idealized world free of transactions costs. I show that the AD model fails even as an idealized model; it actually mistakes the logic of pure capitalism. Unlike McKenzie’s model of idealized general equilibrium under constant returns to scale, Arrow and Debreu claim to have shown the existence of competitive equilibrium under decreasing returns to scale and positive pure profits. The AD model (again unlike the McKinzie model) needs to assign the profits to individuals and this is done using the notion of “ownership of the production set.” But this notion suffers from a fatal ambiguity. If Arrow and Debreu interpret it to mean “ownership of a corporation” then a simple argument in the form “labor can hire capital or capital can hire labor” defeats the alleged necessity of assigning residual claimancy to the corporation. A given corporation may or may not end up exploiting a set of production opportunities (represented by a production set) depending on whether it hires in labor and undertakes production or hires out its capital to others (all by assumption at the parametrically given prices). In the latter case, residual claimancy is elsewhere. There is no such property right as “ownership of a production set” in a private property market economy. The legal party which purchases or already owns all the inputs used up in production has the defensible legal claim on the outputs: there is no need to also “purchase the production set.” At any set of prices that allow positive pure profits, anyone in the idealized AD model could bid up the price of the inputs and thus try to reap a smaller but still positive profit. Therefore,pace Arrow and Debreu, there could be no equilibrium with positive pure profits. In the Appendix, the property rights fallacy that afflicts the AD model is shown to also afflict orthodox capital theory and corporate finance theory.
Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide. (1982)

Various vesicle structures and lipid compositions have been studied to identify the optimal type of liposome for delivery of the macrophage-activating agent muramyl dipeptide (MDP) to macrophages. Evaluation of the ability of liposomes to be phagocytosed by macrophages established that optimal initial rates of engulfment were obtained when multilamellar vesicles (MLV) composed of distearoylphosphatidylcholine (18:0 PC): phosphatidylserine (PS) (7:3 mol ratio) were used. MLV composed exclusively of 18:0 PC were phagocytosed at rates greater than or equal to those of MLV composed of egg phosphatidylcholine (PC):PS, whereas MLV composed only of egg PC were very poorly phagocytosed. Although phagocytosis was enhanced by incorporation of PS into MLV, the inclusion of PS brought about significant enhancement in liposome permeability in the presence of serum. The inclusion of PS, however, was a requirement for the delivery of MLV to the lungs following i.v. injection into mice whether used in conjunction with 18:0 PC or egg PC. Activation of macrophages to become tumoricidal against syngeneic tumor cells wtih liposome-encapsulated MDP was superior in both degree and duration when MLV composed of 18:0 PC:PS (7:3 mol ratio) were used. MLV were found to be superior to large unilamellar vesicles containing equal amounts of lipid and entrapped MDP. On the other hand, higher levels of macrophage activation were obtained when an equivalent amount of a lipophilic MDP derivative, muramyltripeptide:phosphatidylethanolamine, was incorporated into the liposome bilayer irrespective of whether the adjuvant was incorporated in liposomes composed of 18:0 PC:PS or egg PC:PS.
Companding current-mode integrator: A new circuit principle for continuous-time monolithic filters (1990)

A new companding current-mode (CI) integrator principle is proposed. The integrator function is linear despite being composed of nonlinear parts. Its application promises monolithic filters with improved noise performance suitable for low supply voltages. A class AB circuit implementation is proposed which features an extended dynamic range.
Arachidonic acid release in rabbit neutrophils (1989)

[3H]Arachidonic acid is released after stimulation of rabbit neutrophils with fMet-Leu-Phe or platelet-activating factor (PAF). The release is rapid and dose-dependent, and is inhibited in phorbol 12-myristate 13-acetate (PMA)-treated rabbit neutrophils. The protein kinase C (PKC) inhibitor 1-(5-isoquinoline-sulphonyl)-2-methylpiperazine (H-7) prevents this inhibition. In addition, PMA increases arachidonic acid release in H-7-treated cells stimulated with fMet-Leu-Phe. [3H]Arachidonic acid release, but not the rise in the concentration of intracellular Ca2+, is inhibited in pertussis-toxin-treated neutrophils stimulated with PAF. The diacylglycerol kinase inhibitor R59022 increases the concentration of diacylglycerol and potentiates [3H]arachidonic acid release in neutrophils stimulated with fMet-Leu-Phe. This potentiation is not inhibited by H-7. These results suggest several points. (1) A rise in the intracellular concentration of free Ca2+ is not sufficient for arachidonic acid release in rabbit neutrophils stimulated by physiological stimuli. (2) A functional pertussis-toxin-sensitive guanine nucleotide regulatory protein and/or one or more of the changes produced by phospholipase C activation are necessary for arachidonic acid release produced by physiological stimuli. (3) Agents that stimulate PKC potentiate arachidonic acid release, and this potentiation is not inhibited by H-7. These agents produce their actions in part by direct membrane perturbation.
Expedient, High-Yielding Synthesis of Silyl-Substituted Salen Ligands (2007)

Described is an efficient synthesis of silyl-substituted salen ligands, used for the preparation of enantioselective catalysts. The salicylaldehyde precursors are synthesized from the silyl ethers of 2,6-dibromophenols via a one-pot double lithium halogen exchanges, to induce an intramolecular retro-Brook rearrangement and allow introduction of the aldehyde group. Condensation of the salicylaldehyde products with a chiral diamine affords the silyl-substituted salen ligands in high yields. The use of other electrophiles allows easy access to silyl-substituted phenolic esters, ketones, and boronic acids.
<title>Overcoming global topography and improving lithographic performance using a transmittance controlled mask</title> (1994)

As device density increases, topography gets more severe and optical proximity effect becomes worse. If light intensity can be controlled for individual patterns, linewidth variation over topography and optical proximity effect can also be minimized. A new method to solve these problems named transmittance controlled mask (TCM) is proposed. TCM is such a mask that thin absorptive films remain on the areas where light attenuation is necessary. In this paper, TCM is prepared and evaluated in view of topography and optical proximity effect improvement as well as process latitude improvement. Greatly improved process latitude was observed over 1.5 micrometers aluminum topography with TCM, while no process latitude was obtained with conventional masks even over 0.9 micrometers topography. Good optical proximity control is also possible with TCM.
CHANGES IN PROTOPLASMIC CONSISTENCY AND THEIR RELATION TO CELL DIVISION (1919)

1. The development of the amphiaster is associated with the formation of two semisolid masses within the more fluid egg substance. 2. The elongation of the egg during cleavage is possibly produced as a consequence of the mutual pressure of these two growing semisolid masses. 3. The division of the egg into two blastomeres consists essentially in a growth, within the egg, of two masses of material at the expense of the surrounding cytoplasm. When all the cytoplasm of the egg is incorporated in these two masses cleavage occurs. 4. After a certain period of time the semisolid masses revert to a more fluid state. In the eggs studied this normally occurs after the cleavage furrow has completed the separation of the two blastomeres. The formation of the furrow, however, may be prevented in various ways, upon which the egg reverts to a single spherical semifluid mass containing two nuclei. 5. An egg mutilated during its semisolid state (amphiaster stage) may or may not revert to a more fluid state. If the more solid state is maintained, the cleavage furrow persists and proceeds till cleavage is completed. If the mutilation causes the egg to revert to the more fluid state the furrow becomes obliterated and a new cleavage plane is subsequently adopted. 6. The nuclei of eggs in the semifluid state are able to alter their positions. In semifluid mutilated eggs the nuclei tend to move to positions which may assure symmetry in aster formation and cleavage.
<i>Colloquium</i>: Role of the<i>H</i>theorem in lattice Boltzmann hydrodynamic simulations (2002)

In the last decade, minimal kinetic models, and primarily the lattice Boltzmann equation, have met with significant success in the simulation of complex hydrodynamic phenomena, ranging from slow flows in grossly irregular geometries to fully developed turbulence, to flows with dynamic phase transitions. Besides their practical value as efficient computational tools for the dynamics of complex systems, these minimal models may also represent a new conceptual paradigm in modern computational statistical mechanics: instead of proceeding bottom-up from the underlying microdynamic systems, these minimal kinetic models are built top-down starting from the macroscopic target equations. This procedure can provide dramatic advantages, provided the essential physics is not lost along the way. For dissipative systems, one essential requirement is compliance with the second law of thermodynamics. In this Colloquium, the authors present a chronological survey of the main ideas behind the lattice Boltzmann method, with special focus on the role played by the $H$ theorem in enforcing compliance of the method with macroscopic evolutionary constraints (the second law) as well as in serving as a numerically stable computational tool for fluid flows and other dissipative systems out of equilibrium.
Calculation of improvement to HRXRD system through-put using curved graded multilayers (1996)

The necessity to take into consideration the angular size of the x-ray beam and its influence on the parameters of the reflected x-ray beam for ray tracing analysis will be shown.
Analysis of the Volume of Red Blood Cells: Application of the Expectation- Maximization Algorithm to Grouped Data from the Doubly-Truncated Lognormal Distribution (1986)

In accordance with general principles recommended by the International Committee for Standardization in Haematology (1982, Journal of Clinical Pathology 35, 1320-1322), we have developed statistical methods for the analysis of red cell volume distributions. To select an appropriate reference distribution for goodness-of-fit testing, we derived a mathematical model of erythropoiesis that predicted a lognormal form for the distribution of erythrocyte volumes. Model predictions were then tested using samples obtained from 50 healthy individuals. Each grouped red cell volume distribution was doubly-truncated to eliminate artifactual frequency counts. Distribution parameter estimates were computed using the expectation-maximization algorithm, a missing information technique. Results of the one-sample chi-square goodness-of-fit test showed a fairly even distribution of P-values over the interval. Examples of the application of these statistical procedures to distributions from patients with anemia are given. Our results suggest that, for the analysis of red blood cell volumes, (i) parameter estimation should be made with the expectation-maximization method, and (ii) the truncated lognormal distribution should be used as a reference distribution for goodness-of-fit testing. This method could be applied to any set of grouped doubly-truncated data which, after transformation, follows the normal model.
Identification of Endothelial Cells and Progenitor Cell Subsets in Human Peripheral Blood (2010)

An assay for circulating cell subsets in human peripheral blood by flow cytometry is used as a biomarker to determine cardiovascular disease risk and tumor responsiveness to chemotherapy since endothelial progenitor cells (EPCs) function in vasculogenesis and angiogenesis. Despite analytical advances in polychromatic flow cytometry (PFC), conventional approaches are routinely utilized to enumerate and isolate EPCs, which has led to varied results in clinical studies, potential cellular misidentification, and thus a lack of a plausible biological explanation for how purported EPCs function. Herein, a reproducible PFC protocol is provided to identify a rare circulating endothelial colony-forming cell (ECFC) with proliferative potential, along with a population of circulating progenitor cells (CPCs) in which the ratio analysis distinguishes between healthy and disease populations. In sum, a reliable PFC protocol, which can be used to investigate the roles of human hematopoietic and endothelial elements in the growth and maintenance of the vasculature, is described.
A Graph Database Model for Knowledge Extracted from Place Descriptions (2018)

Everyday place descriptions provide a rich source of knowledge about places and their relative locations. This research proposes a place graph model for modelling this spatial, non-spatial, and contextual knowledge from place descriptions. The model extends a prior place graph, and overcomes a number of limitations. The model is implemented using a graph database, and a management system has also been developed that allows operations including querying, mapping, and visualizing the stored knowledge in an extended place graph. Then three experimental tasks, namely georeferencing, reasoning, and querying, are selected to demonstrate the superiority of the extended model.
ATLAS: Automatic Term-level abstraction of RTL designs (2010)

Abstraction plays a central role in formal verification. Term-level abstraction is a technique for abstracting word-level designs in a formal logic, wherein data is modeled with abstract terms, functional blocks with uninterpreted functions, and memories with a suitable theory of memories. A major challenge for any abstraction technique is to determine what components can be safely abstracted. We present an automatic technique for term-level abstraction of hardware designs, in the context of equivalence and refinement checking problems. Our approach is hybrid, involving a combination of random simulation and static analysis. We use random simulation to identify functional blocks that are suitable for abstraction with uninterpreted functions. Static analysis is then used to compute conditions under which such function abstraction is performed. The generated term-level abstractions are verified using techniques based on Boolean satisfiability (SAT) and satisfiability modulo theories (SMT). We demonstrate our approach for verifying processor designs, interface logic, and low-power designs. We present experimental evidence that our approach is efficient and that the resulting term-level models are easier to verify even when the abstracted designs generate larger SAT problems.
Marked variation in the cardiomyopathy associated with Friedreich’s ataxia (1999)

The cardiomyopathy associated with Friedreich's ataxia shows a variable phenotype which is not concordant with the presence of ECG abnormalities or the neurological features of the condition. As the genetic basis for Friedreich's ataxia has been established, further studies will help to clarify the molecular mechanisms of the cardiac hypertrophy.