gebhart/patrepeval huggingface dataset:
Ligand‐Driven Wavelength‐Tunable and Ultra‐Broadband Infrared Luminescence in Single‐Ion‐Doped Transparent Hybrid Materials (2009)

Abstract Here, tuning of the optical properties of emission centers by tailoring the ligand fields is investigated. Experimentally, it is demonstrated that Ni 2+ can act as a single emission species in multiple octahedral local environments. Nanocrystal‐embedded hybrid materials are employed as hosts in order to take advantage of their convenience in local environment design for practical applications. Novel composite gain materials with high transparence are successfully made, and show interesting wavelength‐tunable and ultra‐broadband infrared luminescence covering the whole near‐infrared region from 1 100 to 1 800 nm. The infrared luminescence peak positions can be finely tuned from 1 300 to 1 450 and to 1 570 nm, with the largest full width at half maximum being about 400 nm and covering the telecommunication bands at 1 200–1 500 nm. According to the results of characterization, the unusual luminescence, interestingly, originates from Ni 2+ in nanocrystals and the doping efficiency of Ni 2+ is surprisingly high. The results demonstrate that the method presented may be an effective way to fabricate multifunctional light sources with various fundamental multifunctional applications from efficient broadband optical amplifiers to bio‐imaging.
[An experimental study on the expression and pathogenic effects of cyclooxygenase-2 in nonalcoholic fatty liver disease]. (2008)

环氧合酶-2(COX-2)的过度表达与许多炎症性疾病有关,然而对它在非酒精性脂肪肝(NAFLD)中的表达和作用机制知之甚少.Celecoxib是特异性的COX-2抑制剂[1].我们通过建立大鼠NAFLD动物模型,同时在模型组中给予celecoxib进行干预治疗,研究COX-2在NAFLD中的作用,以便进一步探讨其在NAFLD中的致病机制。
Widespread Distribution of Some Minor Chlorophyll-Protein Complexes in Some Plants and Algae (1981)

The use of the non-ionic detergent octyl beta-d-glucoside has allowed the demonstration in spinach of a chlorophyll a+b-protein complex of apparent molecular weight 29 kilodaltons (Camm and Green, 1980, Plant Physiol 66: 428-432). Complexes analogous to this one also can be demonstrated in three grasses, in dicots of the Chenopodiaceae, Fabaceae, and Asteraceae, and in the siphonaceous green alga Acetabularia mediterranea. These complexes are clearly distinguishable from the light harvesting complex on the basis of the chlorophyll a/b ratio, apparent molecular weight, and polypeptide composition. In addition, most plants surveyed contained two, not one, minor chlorophyll a complexes as well as the chlorophyll a complex of Photosystem I.
Synthesis and bioactivity of novel triazolo [1,5‐<i>a</i>]pyrimidine derivatives[3] (2001)

Abstract In an attempt to discover novel compounds with high herbicidal activity and low toxicity, a series of novel 1,2,4‐triazolo[1,5‐a]pyrimidine derivatives, α‐(5,7‐dimethyl‐1,2,4‐triazolo[1,5‐a]pyrimidine‐2‐thio)acetamides 3 and α‐(5,7‐dimethyl‐1,2,4‐triazolo[1,5‐a]pyrimidine‐2‐sul‐fonyl)acetamides 4 , have been designed and synthesized by a three‐step synthetic route. The structures of all compounds prepared were confirmed by elemental analyses and by 1 H NMR and mass spectroscopy. The results of preliminary bioassay indicate that the title compounds possess good herbicidal activity against rape (Brassica campestris L.) and barnyardgrass (Echinochloca crusgalli L.) © 2001 John Wiley & Sons, Inc. Heteroatom Chem 12:491–496, 2001
Effects of some technologies of curing uncomminuted meat products on their flavour Part 1. Changes in the contents of fatty acids as meat flavour precursors (1989)

Abstract A study was made of the fatty‐acid composition of phospholipids and the fraction of free fatty acids in two uncomminuted pork products, loin and neck, manufactured by three technologies: I, brine curing; 11, dry curing; 111, dry curing using%.6% honey. A higher phospholipid content was found in the loin products. Brine curing caused a more intensive lipid hydrolysis in both types of meat products. The free fatty‐acid fraction in the meat products manufactured by technologies II and III was richer in unsaturated fatty acids, which are some of the most important meatflavour precursors.
A fast motion planning representation for configuration flat robots with applications to micro air vehicles (2017)

Navigation of micro air vehicles (MAVs) in unknown environments is a complex sensing and trajectory generation task, particularly at high velocities. In this work, we introduce an efficient sense-and-avoid pipeline that compactly represents range measurements from multiple sensors, trajectory generation, and motion planning in a 2.5-dimensional projective data structure called an egospace representation. Egospace coordinates generalize depth image obstacle representations and are a particularly convenient choice for configuration flat mobile robots, which are differentially flat in their configuration variables and include a number of commonly used MAV plant models. After characterizing egospace obstacle avoidance for robots with trivial dynamics and establishing limits on applicability and performance, we generalize to motion planning over full configuration flat dynamics using motion primitives expressed directly in egospace coordinates. In comparison to approaches based on world coordinates, egospace uses the natural sensor geometry to combine the benefits of a multiresolution and multi-sensor representation architecture into a single simple and efficient layer.
Towards application security on untrusted operating systems (2008)

Complexity in commodity operating systems makes compromises inevitable. Consequently, a great deal of work has examined how to protect security-critical portions of applications from the OS through mechanisms such as microkernels, virtual machine monitors, and new processor architectures. Unfortunately, most work has focused on CPU and memory isolation and neglected OS semantics. Thus, while much is known about how to prevent OS and application processes from modifying each other, far less is understood about how different OS components can undermine application security if they turn malicious. We consider this problem in the context of our work on Overshadow, a virtual-machine-based system for retrofitting protection in commodity operating systems. We explore how malicious behavior in each major OS subsystem can undermine application security, and present potential mitigations. While our discussion is presented in terms of Overshadow and Linux, many of the problems and solutions are applicable to other systems where trusted applications rely on untrusted, potentially malicious OS components. 1
The insulin‐like growth factor‐I/binding protein axis: physiology, pathophysiology and therapeutic manipulation (1993)

Insulin-like growth factor-I (IGF-I) is a single-chain polypeptide which has multiple metabolic actions and effects on the differentiation and proliferation of a wide variety of cell types. IGF-I has endocrine, paracrine and autocrine actions and is bound in the circulation to a complex system of binding proteins which alter its bioavailability and activity. Thus its physiology is complex and is altered in a number of pathological states. This review will discuss these states and the actual and proposed therapeutic applications of recombinant human IGF-I (rhIGF-I).
Silica‐Templated Synthesis of Ordered Mesoporous Tungsten Carbide/Graphitic Carbon Composites with Nanocrystalline Walls and High Surface Areas via a Temperature‐Programmed Carburization Route (2009)

Ordered mesostructured tungsten carbide and graphitic carbon composites (WC/C) with nanocrystalline walls are fabricated for the first time by a temperature-programmed carburization approach with phosphotungstic acid (PTA) as a precursor and mesoporous silica materials as hard templates. The mesostructure, crystal phase, and amount of deposited graphitic carbon can be conveniently tuned by controlling the silica template (SBA-15 or KIT-6), carburizing temperature (700-1000 degrees C), the PTA-loading amount, and the carburizing atmosphere (CH(4) or a CH(4)/H(2) mixture). A high level of deposited carbon is favorable for connecting and stabilizing the WC nanocrystallites to achieve high mesostructural regularity, as well as promoting the carburization reaction. Meanwhile, large pore sizes and high mesoporosity of the silica templates can promote WC-phase formation. These novel, ordered, mesoporous WC/C nanocomposites with high surface areas (74-169 m(2) g(-1)), large pore volumes (0.14-0.17 cm(3) g(-1)), narrow pore-size distributions (centered at about 3 nm), and very good oxidation resistance (up to 750 degrees C) have potential applications in fuel-cell catalysts and nanodevices.
What Are Functional Ionic Liquids for the Absorption of Acidic Gases? (2013)

As a kind of novel and efficient material, ionic liquids (ILs) are used for capture of acidic gases including SO2 and CO2 from flue gas. Due to very low content of acidic gases in flue gas, it is important to find functional ILs to absorb the acidic gases. However, up to now, there is no criterion to distinguish if the ILs are functional or not before use, which greatly influences the design of functional ILs. In this work, a series of ILs were synthesized and used to determine functional or normal ILs for the capture of acidic gases. It has been found that the pKa of organic acids forming the anion of ILs can be used to differentiate functional ILs from normal ILs for the capture of acidic gases from flue gas. If the pKa of an organic acid is larger than that of sulfurous acid (or carbonic acid), the ILs formed by the organic acid can be called functional ILs for SO2 (or CO2) capture, and it can have a high absorption capacity of SO2 (or CO2) with low SO2 (or CO2) concentrations. If not, the IL is just a normal IL. The pKa of organic acids can also be used to explain the absorption mechanism and guide the synthesis of functional ILs.
Artifact due to <i>B</i><sub>0</sub> fluctuations in fMRI: Correction using the <i>k‐</i>space central line (2001)

Magnetic resonance experiments require the main magnetic field, B(0), to remain very stable. Several external sources, such as moving ferromagnetic objects and/or changing electromagnetic fields, can significantly change the value of B(0) over time. This work describes an apparent displacement along the phase-encoding axis caused by a variation in B(0). This artifact was observed in fMRI images acquired with EPI. The effect was characterized and tested using an immobile phantom. The image displacement motion along the phase-encoding axis closely followed the changes in B(0). The phase of the central line in the Fourier space was successfully used to correct this artifact. Fluctuations in B(0) may result in artifacts that mimic subject head motion, and must be appropriately corrected. Magn Reson Med 46:198-201, 2001.
Edge‐coloring of multigraphs: Recoloring technique (1984)

Abstract New upper and lower bounds for the chromatic index of a finite muitigraph are obtained. A complete description is given of multigraphs satisfying χ′ > 1/8(9ρ + 6) where χ′ and ρ denote the chromatic index and the maximum vertex degree of a multigraph. Some new and old conjectures are discussed.
Studies with Corticotropin. II. Pepsin Degradation of β-Corticotropin (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies with Corticotropin. II. Pepsin Degradation of β-CorticotropinP. H. Bell, K. S. Howard, R. G. Shepherd, B. M. Finn, and J. H. MeisenhelderCite this: J. Am. Chem. Soc. 1956, 78, 19, 5059–5066Publication Date (Print):October 1, 1956Publication History Published online1 May 2002Published inissue 1 October 1956https://pubs.acs.org/doi/10.1021/ja01600a066https://doi.org/10.1021/ja01600a066research-articleACS PublicationsRequest reuse permissionsArticle Views48Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: The Synthesis of 1H‐Pyrroles (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Gazing and Frowning to Computers Can Be Enjoyable (2011)

The present aim is to introduce first results of a new wearable prototype called Face Interface. The prototype was developed to carry both a video-based wearable eye tracker for pointing and a capacitive facial movement detector for selecting objects on a computer screen. The functionality of the prototype was evaluated in a controlled laboratory conditions in pointing and selecting tasks with three target diameters and three pointing distances. Also subjective ratings about the use of the device in interaction were collected. Participants achieved a mean pointing task time of 2.5 seconds with the prototype. This was improved to 1.2 seconds on average when the wearable eye tracker of the prototype was substituted by a commercial desktop eye tracker. The results revealed that target selection using the Face Interface prototype followed the Fitts' law with correlation of r = 0.76. The participants rated the use of the prototype as enjoyable, fast and accurate.
Synergistic Effects of BAY 60-4552 and Vardenafil on Relaxation of Corpus Cavernosum Tissue of Patients with Erectile Dysfunction and Clinical Phosphodiesterase Type 5 Inhibitor Failure (2013)

Despite downregulation of the NO/cGMP/PKG pathway, combining BAY 60-4552 with vardenafil significantly enhanced relaxation HCC strips of PDE5-i nonresponders.
Transition‐metal‐catalyzed reactions of 5‐methylene‐2‐oxazolidinone and 5‐methylene‐1,3‐thiazolidine‐2‐thione with isocyanates (2003)

Abstract 5‐Methylene‐2‐oxazolidinone (1) and 5‐methylene‐1,3‐thiazolidine‐2‐thione (4) react with various isocyanates to give the corresponding urethanes 3 and 5 in high yields in the presence of palladium(0) or palladium(II) catalyst under mild reaction conditions. A mechanism is proposed. Copyright © 2003 John Wiley & Sons, Ltd.
Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling in Continuous Flow (2017)

Carbon–carbon cross-coupling reactions are among the most important processes in organic chemistry and Suzuki–Miyaura reactions are the most widely used protocols. For a decade, green chemistry and particularly catalysis and continuous flow, have shown immense potential in achieving the goals of “greener synthesis”. To date, it seems difficult to conceive the chemistry of the 21st century without the industrialization of continuous flow process in the area of pharmaceuticals, drugs, agrochemicals, polymers, etc. A large variety of palladium Suzuki–Miyaura cross-coupling reactions have been developed using a continuous flow sequence for preparing the desired biaryl derivatives. Our objective is to focus this review on the continuous flow Suzuki–Miyaura cross-coupling using homogeneous and heterogeneous catalysts.
ESTABLISHMENT OF A CLONAL STRAIN OF HEPATOMA CELLS WHICH SECRETE ALBUMIN (1969)

A clonal strain of epithelial cells (designated MH(1)C(1)) has been established from the transplantable Morris hepatoma No. 7795. The cells have maintained distinctive morphology throughout more than 20 subcultures (split 1:5) at 2- to 4-week intervals in supplemented Ham's F 10 medium. They contain many highly refractile, round, cytoplasmic bodies which stain bright red with Oil Red O. The population doubling time was 2 wk when the clonal strain was first established. It has gradually decreased to 1 wk. The cells synthesize rat serum albumin and secrete it into the culture medium as determined immunologically by microcomplement fixation and double diffusion. Albumin secretion (3-6 microg albumin/mg cell nitrogen/24 hr) occurs throughout the logarithmic phase of cell proliferation and has not diminished during serial propagation since the strain was initiated 15 months ago.
PREPARATION AND GRAPHITIZATION OF HIGH-PERFORMANCE CARBON FOAMS FROM COAL (2014)

Coal-based carbon foams are proving to be an attractive, multifunctional engineering material for numerous thermal, mechanical, and electrical applications. They offer the performance of three-dimensional carbon fiber
Ocular Safety of INS365 Ophthalmic Solution: A P2Y <sub>2</sub> Agonist In Healthy Subjects (2001)

The purpose of this study was to evaluate the ocular safety and tolerability of the P2Y(2) receptor agonist, INS365, when applied as eye drops in normal human subjects. This study was a double-masked, placebo-controlled, randomized, within subject paired-comparison, dose-escalation study in five cohorts of ten healthy subjects. The concentrations of INS365 ophthalmic solution were 0.5, 1.0, 2.0, and 5.0% given three times over six hours. Safety was assessed by general and ophthalmic examination and symptomatology. Unanesthetized Schirmer tests were performed in the last cohort of 10 subjects to evaluate the acute effects of INS365 on tear secretion. There were no significant differences in the number of subjects with ocular events reported in placebo-treated eyes compared to INS365-treated eyes. Two adverse events were possibly related to INS365: painless blepharospasm and an increase in lacrimation after 5.0% INS365 instillation. Unanesthetized Schirmer testing showed no acute effects of INS365 on tear secretion, compared to its vehicle, in healthy subjects, in which reflex tearing often produced maximal Schirmer values. INS365 ophthalmic solution was well-tolerated when administered by ocular instillation. Stimulation of ocular surface P2Y(2) receptors was not associated with ocular tolerability issues in healthy subjects.
Preselection Thymocytes Are More Sensitive to T Cell Receptor Stimulation Than Mature T Cells (1998)

During T cell development, thymocytes which are tolerant to self-peptides but reactive to foreign peptides are selected. The current model for thymocyte selection proposes that self-peptide-major histocompatibility complex (MHC) complexes that bind the T cell receptor with low affinity will promote positive selection while those with high affinity will result in negative selection. Upon thymocyte maturation, such low affinity self-peptide-MHC ligands no longer provoke a response, but foreign peptides can incidentally be high affinity ligands and can therefore stimulate T cells. For this model to work, thymocytes must be more sensitive to ligand than mature T cells. Contrary to this expectation, several groups have shown that thymocytes are less responsive than mature T cells to anti-T cell receptor for antigen (TCR)/CD3 mAb stimulation. Additionally, the lower TCR levels on thymocytes, compared with T cells, would potentially correlate with decreased thymocyte sensitivity. Here we compared preselection thymocytes and mature T cells for early activation events in response to peptide-MHC ligands. Remarkably, the preselection thymocytes were more responsive than mature T cells when stimulated with low affinity peptide variants, while both populations responded equally well to the antigenic peptide. This directly demonstrates the increased sensitivity of thymocytes compared with T cells for TCR engagement by peptide-MHC complexes.
Preparation and Evaluation of Sulfide Derivatives of the Antibiotic Brefeldin A as Potential Prodrug Candidates with Enhanced Aqueous Solubilities (2001)

Several sulfide (+)-brefeldin A (BFA) analogues were prepared through the Michael addition of various thiols. Many of the sulfides were also oxidized to the corresponding sulfoxide with m-CPBA. The sulfides were designed to act as BFA prodrugs via the metabolic oxidation to the sulfoxide and subsequent syn elimination. Kinetic experiments were used to prove that the syn elimination of the sulfoxides prepared did in fact take place. Five selenide BFA prodrugs were also prepared that are envisioned to act in the same manner as the sulfides. As expected, when oxidation of the selenide to selenoxide was attempted, in situ syn elimination was observed. All of the compounds prepared were evaluated for antiproliferative activity against human cancer cell lines in the National Cancer Institute screen. The sulfoxides were much more potent than either the sulfides or selenides. Especially notable were sulfoxide 21, which possessed a cytotoxicity mean graph midpoint value (MGM) value lower than BFA itself, and sulfoxide 22, which possessed an MGM value slightly less potent than that of BFA. The sulfide analogues were shown to possess increased aqueous solubilty with respect to BFA.
Velocity estimation for depth conversion of a 3‐D data set in Troll field: A comparison of different techniques (1994)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1994Velocity estimation for depth conversion of a 3‐D data set in Troll field: A comparison of different techniquesAuthors: David McCorkindaleLong‐far HwangDavid McCorkindaleConoco and Long‐far HwangConocohttps://doi.org/10.1190/1.1932135 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1932135FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1994ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1994 Pages: 1679 publication data© 1994 Copyright © 1994 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 10 Feb 2005 CITATION INFORMATION David McCorkindale and Long‐far Hwang, (1994), "Velocity estimation for depth conversion of a 3‐D data set in Troll field: A comparison of different techniques," SEG Technical Program Expanded Abstracts : 487-490. https://doi.org/10.1190/1.1932135 Plain-Language Summary PDF DownloadLoading ...
Personal distributed computing: the Alto and Ethernet software (1986)

The personal distributed computing system based on the Alto and the Ethernet was a major effort to make computers help people to think and communicate. The paper describes the complex and diverse collection of software that was built to pursue this goal, ranging from operating systems, programming environments, and communications software to printing and file servers, user interfaces, and applications such as editors, illustrators, and mail systems.
Concordance and recessive inheritance of Leber congenital amaurosis (1993)

Pedigrees were obtained on 43 patients with confirmed Leber congenital amaurosis, a rare form of blindness caused by congenital dysfunction of the retina. All of the pedigrees were consistent with autosomal recessive inheritance and the segregation frequency using classical segregation analysis was 0.24 +/- 0.07. Six of the 7 affected sib pairs were concordant in regards to systemic abnormalities. Despite previous reports that Leber congenital amaurosis can be inherited either as an autosomal dominant or recessive condition, our findings support only an autosomal recessive inheritance of this disorder.
Corneal epithelial-specific cytokeratin 3 is an autoantigen in Wegener's granulomatosis-associated peripheral ulcerative keratitis. (1999)

This evidence suggests that the 66-kDa autoantigen (BCEA-A) associated with PUK in WG is cytokeratin 3, and this may form the basis of a diagnostic/prognostic test.