gebhart/patrepeval huggingface dataset:
Sparse Estimation of Spectral Lines: Grid Selection Problems and Their Solutions (2011)

Grid selection for sparse estimation of spectral-line parameters is a critical problem that was in need of a satisfactory solution: assuming the usual case of a uniform spectral grid how should one select the number of grid points, K? We first present a simple practical rule for choosing an initial value (or initial values) of it in a given situation. Then, we go on to explain how the estimation results corresponding to different values of K can be compared with one another and therefore how to select the "best" value of K among those considered. Furthermore, we introduce a method for detecting when a grid is "too rough" and for obtaining refined parameter estimates in such a case.
Voice Disorders in the General Population: Prevalence, Risk Factors, and Occupational Impact (2005)

The results of this large epidemiologic study provide valuable information regarding the prevalence of voice disorders, factors that contribute to voice disorder vulnerability, and the functional impact of voice problems on the general population.
Spontaneous hepatocellular neoplasms and hepatic hemangiosarcomas in several strains of mice. (1982)

The incidence of spontaneous liver tumors, ratio of hepatocellular adenomas to carcinomas, degree of differentiation of hepatocellular carcinomas, and incidence of pulmonary metastases in several strains of mice from different experiments were examined. Hepatocellular tumors were rare in all strains before 12 months of age and then increased with age. They were more common in male than in female mice. Pulmonary metastases were rare before 24 months of age and occurred in 10 of 221 mice with hepatocellular carcinomas (4.5%); their incidence in different strains was not strikingly different. Hepatic vascular tumors were less common than hepatocellular tumors. No tumors of bile duct origin were observed in these mice.
Monitoring emerging IPv6 wireless access networks (2005)

Foreseeing a future where IPv6 and mobile terminals play an important role in public access communication networks, this article introduces a monitoring system capable of identifying relevant traffic flows and tracking them while terminal equipment moves between network attachment points. The mobile flows are characterized and represented so that individual users and flows can perceive the quality of service they receive, and operators can have global traffic views of their heterogeneous access networks.
On adaptive spatial-temporal processing for airborne surveillance radar systems (1994)

Implementing the optimum spatial-temporal (angle-Doppler) processor involves two crucial issues: the selection of processing configurations, and the development of adaptive algorithms which can efficiently approach the performance potential of the selected configuration. Among the three available configurations, the joint-domain, the cascade space-time, and the cascade time-space, this work shows that, in contrast to a popular belief, the detection performance potentials of both cascade configurations can fall far below that of the joint-domain optimum. In addition, this work presents a new adaptive algorithm, called the Joint-Domain Localized Generalized Likelihood Ratio detection (JDL-GLR), which is data efficient i.e., with fast convergence to the joint-domain optimum, as well as computationally efficient, together with such desirable features as the embedded constant false-alarm rate (CFAR) and robustness in non-Gaussian interference.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Original HCI surface treatment for diffusion bonding of nickel superalloy specimens (1978)

Nickel superalloys containing Ti and Chave shown considerable precipitation of TiC at bond interfaces during solid-state bonding operations, i.e. diffusion bonding and hot isotatic pressing (HIP). To enhance surface bond ability a new surface treatment has been developed which completely depletes the Ti (and Al) at the metal surface to a controllable depth by the use of a H2-HCI atmosphere. It has been shown that the draining rate of the alloying elements is controlled by the degree of material surface reactivity with HCI. A detailed examination of HIP and cast IN 100 andforged Waspaloy after H2-HCI treatment is presented and an extension of the treatment to HIP and forged René 95 and forged INCO 718 is also included. In general, a treated depth from 25 to 30 μm was found to be beneficial in subsequent bonding operations. Metallographical observations on control and pretreated specimens showedgreatly improved recrystallization and the absence of precipitated TiC in the, bonding zone.
Characteristics of Model Polyelectrolyte Multilayer Films Containing Laponite Clay Nanoparticles (2009)

Polyelectrolyte films structure formed by the "layer-by-layer" (LbL) technique can be enriched by addition of charged nanoparticles like carbon nanotubes and silver or hydroxyapatite nanoparticles, which can improve properties of the polyelectrolyte films or modify their functionality. In our paper we examined the formation and properties of model polyelectrolyte multilayers containing a synthetic layered silicate, Laponite. The Laponite nanoparticles were incorporated into multilayer films, which were formed from weak, branched polycation PEI and strong polyanion PSS. Since charge of PEI is pH-dependent, we build up multilayer films in two deposition conditions: pH = 6 when PEI was strongly charged and pH = 10.5 when charge density of PEI was low. Thicknesses of the films constructed with various numbers of Laponite layers were measured by single wavelength ellipsometry. We also determined the differences in permeability for selected electroactive molecules using cyclic voltamperometry. Properties of the films containing clay nanoparticles were compared with model polyelectrolyte multilayer films PEI/PSS formed at the same conditions. We found that Laponite nanoparticles strongly influenced PEI/PSS multilayer film properties. Replacement of PSS by Laponite eliminated the oscillations of the film thickness in the case when PEI was weakly charged. PSS layer adsorbed on top of PEI/Laponite bilayers increased the thickness of multilayer films and improved their barrier properties so synergistic effects between these properties for polyelectrolytes and Laponite nanoparticles could be observed.
Synthesis of a silk-inspired peptide–oligothiophene conjugate (2004)

The first example of an oligothiophene-peptide conjugate, which was obtained by solid-phase acylation of a resin-bound silk-inspired oligopeptide sequence with a carboxylic acid functionalized regioregular tetra(3-hexylthiophene) derivative, is reported.
Low-temperature sputtering of crystalline TiO2 films (2006)

This article reports on the investigation of reactive magnetron sputtering of transparent, crystalline titanium dioxide films. The aim of this investigation is to determine a minimum substrate surface temperature Tsurf necessary to form crystalline TiO2 films with anatase structure. Films were prepared by dc pulsed reactive magnetron sputtering using a dual magnetron operating in bipolar mode and equipped with Ti(99.5) and ceramic Ti5O9 targets. The films were deposited on unheated glass substrates and their structure was characterized by x-ray diffraction and surface morphology by atomic force microscopy. Special attention is devoted to the measurement of Tsurf using thermostrips pasted to the glass substrate. It was found that (1) Tsurf is considerably higher (approximately by 100°C or more) than the substrate temperature Ts measured by the thermocouple incorporated into the substrate holder and (2) Tsurf strongly depends on the substrate-to-target distance ds-t, the magnetron target power loading, and the thermal conductivity of the target and its cooling. The main result of this study is the finding that (1) the crystallization of sputtered TiO2 films depends not only on Tsurf but also on the total pressure pT of sputtering gas (Ar+O2), partial pressure of oxygen pO2, the film deposition rate aD, and the film thickness h, (2) crystalline TiO2 films with well developed anatase structure can be formed at Tsurf=160°C and low values of aD≈5nm∕min, (3) the crystalline structure of TiO2 film gradually changes from (i) anatase through (ii) anatase+rutile mixture, and (iii) pure rutile to x-ray amorphous structure at Tsurf=160°C and pT=0.75Pa when pO2 decreases and aD increases above 5nm∕min, and (4) crystallinity of the TiO2 films decreases with decreasing h and Tsurf. Interrelationships between the structure of TiO2 film, its roughness, Tsurf, and aD are discussed in detail. Trends of next development are briefly outlined.
Whole Saliva Proteolysis (2007)

Whole saliva (WS) protein profiles differ significantly from those of glandular salivary secretions. Rapid proteolysis of the prominent members of the salivary protein families by WS resident proteases appears to be a major cause for the observed differences. We propose that the rate and mode of glandular salivary protein degradation in the oral cavity contains information that could be of unique value in the diagnosis of oral disease.
Ad Paulinum Aquileiensem adnotatiunculae (1961)

Aquileiensi patriarchae, anno ncecii mortuo, attribuere conati sumus in libro qui La poesie latine rythmique du haut moyen age inscribitur (Stockholm 1953, P. 94 ss.).Cuius stropha 12 in codice Veronensi 9o quo solo traditur ita scripta est :.Vita nostra resurrexit de sepulcro, cum quam simul
Stress-rupture strength of alloy 718 (1996)

Alloy 718 is the most widely used of the nickel-base superalloys in aerospace applications such as compressor and turbine disks, cases, compressor blades and fasteners in aircraft gas-turbine engines. Since the development of the superalloy by Inco Alloys International over 30 years ago, researchers have made many slight modifications in chemical composition, and have refined process techniques to achieve further improvements in performance. Relatively little information on the effects of phosphorus has been published, and the available information is contradictory. However, phosphorus in superalloys is generally considered detrimental, and by specification is controlled to a low maximum value (0.015% max, for example, in AMS5662 E). This lack of data is the basis of a study by Teledyne Allvac to determine the effects of the interaction of phosphorus, boron, and carbon on the mechanical properties, processing characteristics, and microstructure of Allvac 718. Results show that a significant improvement in stress-rupture properties over those of a commercial Alloy 718 material is possible by optimizing phosphorus, boron, and carbon additions.
(Zr,Hf)Co(Sb,Sn) half-Heusler phases as high-temperature (&gt;700°C) p-type thermoelectric materials (2008)

By substituting Sn for Sb, the potential of stable (Zr,Hf)Co(Sb,Sn) half-Heusler phases, as p-type thermoelectric materials, for high-temperature power generation has been examined. Sn concentration as much as ∼20%–30% is required to realize high power factor values. Substitution of heavier Hf, which reduces the thermal conductivity (κ) via mass fluctuation scattering, nonetheless maintains high mobility. As a result, the thermoelectric figure of merit ZT, for these not-yet-optimized materials, which we found to be ZT=0.5 at 1000K (measured) and ZT=0.6 at 1100K (extrapolated), surpasses the industry benchmark for a p-type material set by SiGe alloys.
Choice control and safety: The royal commission sends the national disability insurance scheme (NDIS) a message on violence (2016)

We have 'a disturbing culture of acceptance of violence against people with disabilities' reports the Royal Commission into Family Violence (RCFV). People with disabilities are recognised as being at higher risk of family violence by the Commission and in National Disability Insurance Scheme (NDIS) consultations.
Dopamine D3 Receptor Partial Agonists and Antagonists as Potential Drug Abuse Therapeutic Agents (2005)

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTDopamine D3 Receptor Partial Agonists and Antagonists as Potential Drug Abuse Therapeutic AgentsAmy Hauck Newman, Peter Grundt, and Michael A. NaderView Author Information Medicinal Chemistry Section, National Institute on Drug AbuseIntramural Research Program, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, and Departments of Physiology/Pharmacology & Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1083 Cite this: J. Med. Chem. 2005, 48, 11, 3663–3679Publication Date (Web):April 21, 2005Publication History Received26 October 2004Published online21 April 2005Published inissue 1 June 2005https://pubs.acs.org/doi/10.1021/jm040190ehttps://doi.org/10.1021/jm040190ereview-articleACS PublicationsCopyright © 2005 American Chemical SocietyRequest reuse permissionsArticle Views1940Altmetric-Citations164LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Amines,Antagonists,Pharmaceuticals,Receptors,Selectivity Get e-Alerts
Cytoplasmic Poly(A) Binding Proteins Regulate Telomerase Activity and Cell Growth in Human Papillomavirus Type 16 E6-Expressing Keratinocytes (2010)

The high-risk human papillomavirus (HPV) E6 and E7 oncoproteins are critical to the immortalization of keratinocytes. HPV type 16 (HPV16) E6 interacts with endogenous proteins to activate hTERT, the catalytic subunit of telomerase, thus avoiding cellular senescence signals. NFX1-123, the longer splice variant of NFX1, interacts with HPV16 E6, as well as cytoplasmic poly(A) binding proteins 1 and 4 (PABPC1 and PABPC4). HPV16 E6 affects hTERT expression posttranscriptionally through NFX1-123, as NFX1-123 interacts with hTERT mRNA and stabilizes it, leading to greater telomerase activity. The PAM2 motif of NFX1-123, with which it binds PABPCs, is required for the posttranscriptional regulation of hTERT by HPV16 E6 and NFX1-123. There is increasing evidence that RNA and DNA viruses utilize RNA-processing proteins, and specifically PABPCs, in the normal virus life cycle, and there is also evidence that RNA-processing proteins are perturbed in cancers. Here, we show that PABPCs are critical in hTERT regulation by HPV16 E6. Although the amount and cellular localization of PABPCs were largely unchanged in cervical cancer cell lines with or without HPV16 and in human foreskin keratinocytes (HFKs) with or without HPV16 E6, knockdown of PABPCs decreased hTERT mRNA and telomerase activity and overexpression of PABPC4 increased these in HPV16 E6-expressing HFKs. In contrast, knockdown of PABPCs in C33A cells had no effect on hTERT mRNA or telomerase activity. Additionally, overexpression of PABPC4 and hTERT led to greater growth of cultured HPV16 E6-expressing HFKs. This is the first evidence that PABPCs have a targeted role in hTERT regulation leading to a growth advantage in cells expressing HPV16 E6.
No clear answers on monoculture issues (2003)

The Computer and Communications Industry Association (CCIA) recently released a report that questioned monoculture's effect on cybersecurity. The report's central idea is that if everyone is running the same hardware and software (a monoculture), a single attack could compromise every machine on the Internet. We obviously need to avoid such a situation, but implying that monoculture is the main cause and destroying monoculture the cure is naive.
Hydrogen Bonding: A Theoretical Perspective (1997)

Because of the importance of the hydrogen bond, there have been scores of insights gained about its fundamental nature by quantum chemical computations over the years. Such methods can probe subtle characteristics of the electronic structure and examine regions of the potential energy surface that are simply not accessible by experimental means. The maturation of the techniques, codes, and computer hardware have permitted calculations of unprecedented reliability and rivaling the accuracy of experimental data. This book strives first toward an appreciation of the power of quantum chemistry to analyze the deepest roots of the hydrogen bond phenomenon. It offers a systematic and understandable account of decades of such calculations, focusing on the most important findings. This book provides readers with the tools to understand the original literature, and to perhaps carry out some calculations of their very own on systems of interest.
Bissulfosuccinimidyl Esters of Aliphatic Dicarboxylic Acids: A New Class of ‘Affinity Directed’ ββ Crosslinkers of HbA (1994)

The potential of sulfosuccinimidyl ester of suberic acid as an intramolecular crosslinker of HbA, directed to the positive charge rich domain of the protein (DPG pocket) has been investigated. The suberate ester introduced crosslinks between the beta-chains and inhibited the dissociation of HbA into alpha beta dimers. The facile crosslinking reaction seen with this suberate ester as compared to the absence of crosslinking with the diaspirin derivative of suberic acid suggests the strong 'steering' influence of the sulfosuccinimidyl moiety of the reagent to the targeted site. The application of this crosslinking approach in the preparation of Hb based blood substitutes is discussed.
A new function of kininogens as thiol‐proteinase inhibitors: inhibition of papain and cathepsins B, H and L by bovine, rat and human plasma kininogens (1985)

The amidolytic activities of papain and rat liver cathepsins B, H and L were strongly inhibited by high (HMM) and low (LMM) molecular mass kininogens from bovine, human and rat plasmas, and their Ki values were estimated to be in the order of 10(-10) - 10(-11)M for papain and 10(-8) - 10(-9)M for cathepsins. The derivatives of bovine kininogens, HMM kinin-free protein, HMM kinin- and fragment 1 X 2-free protein, and LMM kinin-free protein also showed strong inhibitory activity toward these thiol-proteinases. These results suggest that a reactive site which interacts with thiol-proteinases is contained in the heavy chain portion in kininogens.
Very low-loss GeO <sub>2</sub> -doped silica waveguides fabricated by flame hydrolysis deposition method (1990)

GeO2-doped silica single-mode waveguides are fabricated by flame hydrolysis deposition and reactive ion-etching methods, and the loss value measured using a 40 cm long waveguide circuit. The fabricated single-mode waveguides with fourteen 90° bends with a small bending radius of 5 mm have a very low loss value of 0.04 dB/cm, leading to an estimated propagation loss in the straight waveguides part of (0.01 ± 0.01)dB/cm.
Structure and properties of regenerated cellulose/tourmaline nanocrystal composite films (2003)

Abstract Nanocomposite films were successfully prepared from cellulose and tourmaline nanocrystals with mean diameters of 70 nm in a 1.5 M NaOH/0.65 M thiourea aqueous solution by coagulation with 5 wt % CaCl 2 and then a 3 wt % HCl aqueous solution for 2 min. The structure and properties of the composite films were characterized by X‐ray diffraction, scanning electron microscopy, transmission electron microscopy, dynamic mechanical analysis (DMA), differential scanning calorimetry (DSC), and tensile testing. The results indicated that the tourmaline nanocrystals were dispersed in a cellulose matrix, maintaining the original structure of the nanocrystals in the composite films. The loss peaks (tan δ) in the DMA spectra and the decomposition temperatures in the DSC curves of the composite films were significantly shifted toward low temperatures, suggesting that the nanocrystals broke the partial intermolecular hydrogen bonds of cellulose, and this led to a reduction in the thermal stability. However, the nanocomposite films exhibited a homogeneous structure and dispersion of the nanocrystals. When the tourmaline content was in the range of 4–8 wt %, the composite films possessed good tensile strength (92–107 MPa) and exhibited obvious antibacterial action against Staphylococcus aureus . This work provides a potential way of preparing functional composite films or fibers from cellulose and nanoinorganic particles with NaOH/thiourea aqueous solutions. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 42: 367–373, 2004
Function of Siglec‐8 on human eosinophils (2004)

Summary Eosinophil recruitment and activation are regarded as central to the pathophysiology of allergic diseases, including asthma. An improved understanding of the mechanisms involved in these responses is therefore of great relevance to asthma pathogenesis and the development of new therapeutics. As part of ongoing efforts to discover novel eosinophil‐specific molecules, we recently cloned Siglec‐8 (formerly called sialoadhesin family member‐2) from a human eosinophil cDNA library. Siglecs (sialic acid binding Ig‐like lectins) are a family of transmembrane, I‐type lectins characterized by an N‐terminal V‐set Ig domain that binds sialic acid. We now know that Siglec‐8 is expressed only on human eosinophils, basophils and mast cells, giving it a unique expression pattern on effector cells of allergic disease. We have determined that in eosinophils, Siglec‐8 exists in two isoforms, one of which contains two putative cytoplasmic tyrosine‐based signalling motifs, including an ITIM (immunoreceptor tyrosine‐based inhibitory motif) sequence. Because of the ITIM sequence, we hypothesized that Siglec‐8 ligation would inhibit eosinophil functions. Initial studies found that incubation of eosinophils with Siglec‐8 binding monoclonal antibodies under cross‐linking conditions caused rapid and profound caspase‐dependent apoptosis, and this response could not be rescued by the survival‐promoting cytokine interleukin (IL)‐5. In fact, IL‐5 enhanced the ability of Siglec‐8 cross‐linking to induce eosinophil apoptosis. Activation via Siglec‐8 could potentially be used to inhibit eosinophil survival in vivo , providing a novel strategy for reducing or inhibiting these cells in allergic and other diseases.
Learning Deep Representation with Large-Scale Attributes (2015)

Learning strong feature representations from large scale supervision has achieved remarkable success in computer vision as the emergence of deep learning techniques. It is driven by big visual data with rich annotations. This paper contributes a large-scale object attribute database that contains rich attribute annotations (over 300 attributes) for ~180k samples and 494 object classes. Based on the ImageNet object detection dataset, it annotates the rotation, viewpoint, object part location, part occlusion, part existence, common attributes, and class-specific attributes. Then we use this dataset to train deep representations and extensively evaluate how these attributes are useful on the general object detection task. In order to make better use of the attribute annotations, a deep learning scheme is proposed by modeling the relationship of attributes and hierarchically clustering them into semantically meaningful mixture types. Experimental results show that the attributes are helpful in learning better features and improving the object detection accuracy by 2.6% in mAP on the ILSVRC 2014 object detection dataset and 2.4% in mAP on PASCAL VOC 2007 object detection dataset. Such improvement is well generalized across datasets.