gebhart/patrepeval huggingface dataset:
Plasma protein-bound sialic acid in patients with colorectal polyps of known histology (1991)

Protein-bound sialic acid (PBSA) was measured in serial plasma specimens from 62 healthy subjects, 48 patients with colorectal polyps, and 30 patients with colorectal adenocarcinomas. The mean plasma PBSA concentration in healthy smokers was significantly greater than that in healthy nonsmokers and healthy ex-smokers (P less than 0.0001). Villoglandular polyps were associated with higher plasma PBSA values than were the most benign hyperplastic polyps (P less than 0.025). Patients with the most neoplastic villoglandular and villous polyps had significantly greater (P less than 0.010-0.050) plasma PBSA values than healthy subjects. Polypectomy decreased the mean PBSA value significantly to the mean value for healthy subjects only for patients with villoglandular (P less than 0.010) or villous (P less than 0.050) polyps. Colorectal cancer patients had mean plasma PBSA concentrations significantly greater than those for the healthy subjects (P much less than 0.001) and the polyp patients (P much less than 0.001). Surgery significantly reduced (P less than 0.025) the mean PBSA value for the cancer patients to the mean PBSA value observed for the healthy subjects.
[Study on association of vascular endothelial growth factor with the pathogenesis of pregnancy induced hypertension]. (2001)

These findings suggested that the abnormal expression of VEGF in PIHs occurred within the low-stream of genic transcription. It was considered that the abnormal expression of VEGF may play an important role in the pathogenesis of placental ischemia in PIHs.
Software-defined networking of Linux containers (2014)

Today's IT organizations who act as service providers are under increasing pressure to keep up with the continuous and growing demand for IT services. Through the shift from interactive, manual processes to automated, self-deployment of resources, the providers can increase the efficiency of delivering on-demand services. Virtualized resources, particularly virtual machines and containers that are in the focus of the present paper, make the infrastructure transparent to the final user, are easier to be configured and can seamlessly migrate to another host, in real time - preserving processes status. The Linux containers represent an emerging technology for fast and lightweight process virtualization. Because the containers require less resources to run by sharing the operating system kernel, a higher density of containers can be achieved on the same host, opposed to other virtualization solutions like hardware or para-virtualization. The paper presents a solution to enable the on-demand provisioning of Linux containers using Software-Defined Networking, a flexible approach to treating even control-level resources “as a Service”.
Activation of Transcription by Recombinant Upstream Stimulatory Factor 1 Is Mediated by a Novel Positive Cofactor (1995)

The transcription factor USF1 belongs to the family of basic helix-loop-helix proteins that are involved in the regulation of various important cellular processes. Here we characterized the factors involved in the activation of transcription by upstream stimulatory factor 1 (USF1) in a reconstituted class II gene transcription system. Activation of transcription by both wild type USF1 and a GAL-USF (amino acids 1-94 of the yeast activator protein GAL4 fused to amino acids 17-196 of USF) fusion protein required the presence of at least one positive cofactor. A novel positive cofactor (PC5) that functions specifically through the activation domain of USF1 was partially purified and biochemicaly distinguished from previously described positive cofactors. The mechanism by which PC5 mediates activation of transcription through USF1 was investigated in order-of-addition experiments. PC5 had to be present during binding of transcription factor (TF) IID to the TATA box to observe transcriptional activation. However, this event alone did not result in transcriptional activation, which also required the presence of the activator and of PC5 after binding of TFIID. Hence, PC5 may enter transcription during binding of TFIID to function in concert with the activator during subsequent steps in transcription.
Chitin and Chitosan: Marine Biopolymers with Unique Properties and Versatile Applications (2011)

Chitin and chitosan are unique and typical marine polysaccharides waiting for future development and have been attracted the interest of many researchers from various disciplines. Chitin and its derivatives exhibit a variety of physicochemical and biological properties resulting in numerous applications in areas ranging from waste water treatment to agrochemical, environemental and industrial uses. In addition to its lack of toxicity and allergenicity, its biocompatibility, biodegradability and bioactivity make it a very attractive substance for diverse applications as a biomaterial in the pharmaceutical and medical fields. In the present study, chitin and chitosan properties will be reviewed and their potentialities as promising biomaterials also will be discussed.
Scale-Invariant Features for 3-D Mesh Models (2012)

In this paper, we present a framework for detecting interest points in 3-D meshes and computing their corresponding descriptors. For that, we propose an intrinsic scale detection scheme per interest point and utilize it to derive two scale-invariant local features for mesh models. First, we present the scale-invariant spin image local descriptor that is a scale-invariant formulation of the spin image descriptor. Second, we adapt the scale-invariant feature transform feature to mesh data by representing the vicinity of each interest point as a depth map and estimating its dominant angle using the principal component analysis to achieve rotation invariance. The proposed features were experimentally shown to be robust to scale changes and partial mesh matching, and they were compared favorably with other local mesh features on the SHREC'10 and SHREC'11 testbeds. We applied the proposed local features to mesh retrieval using the bag-of-features approach and achieved state-of-the-art retrieval accuracy. Last, we applied the proposed local features to register models to scanned depth scenes and achieved high registration accuracy.
Evaluation of Tropical Maize Germ Plasm for Resistance to Kernel Colonization by Fusarium moniliforme (1989)

(...)Thirty-four tropical inbreds were topcrossed to two corn belt testers and were combined with eight commercial hybrids. The hybrids were evaluated at two locations in North Carolina during the summer of 1985.(...) Significant differences were found among hybrids for resistance to colonization by F. m. (...) The results indicate that tropical germ plasm may be a source of resistance to this pathogen(...)
Polyarylenes and poly(arylenevinylene)s, 3. Oligomeric model compounds for poly(9,10‐anthrylenevinylene) (1990)

Abstract Some reactions for the synthesis of poly(phenylenevinylene), PPV, are examined for their capability to form poly(9,10‐anthrylenevinylene). The reasons for the failure of these reactions are described. Soluble oligomers with up to seven anthracene units are synthesized. The properties of the oligomers are studied and conclusions for the properties of poly(9,10‐anthrylenevinylene), PAV, are drawn.
Garden tour of the medical center at UCLA (1963)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Synthesis of diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates (2015)

The Kabachnik–Fields reaction of 4-piperidone hydrochloride monohydrate, an aromatic aldehyde and triethyl phosphite in the presence of triethylamine and magnesium perchlorate affords diethyl (aryl)(4-oxopiperidin-1-yl)methylphosphonates in moderate yields.
Osteoblasts promote engraftment of allogeneic hematopoietic stem cells. (1998)

Hematopoietic progenitor cells (low density, lineage negative [Lin-], depleted of CD4+, CD8+, B220+, Gr-1+, Mac-1+, CD71+, and Thy1.2+ cells) can engraft lethally irradiated mice when transplanted within, but not across the major histocompatibility (MHC) antigen barrier. We hypothesized that our progenitor cell preparation required "supportive" cells/factors for successful engraftment. Our initial candidate supportive cells, dendritic cells, failed to facilitate engraftment of stem cells across fully allogeneic MHC barriers. Because interaction of stem cells with bone marrow (BM) stromal microenvironment is required for development, maturation, and differentiation of hematopoietic stem cells, and because bone transplants have been found to facilitate BM transplantation (BMT) in some strain combinations, we tested bone progenitor cells, osteoblasts, as facilitators of allogeneic stem cell engraftment. Osteoblasts, purified from donor murine long bones, were cotransplanted with marrow stem cells into fully allogeneic mouse strains. The transplanted mice demonstrated excellent long-term survival, were free of disease, and were entirely engrafted with cells of donor origin. Histologic sections of thymuses and spleens showed full reconstitution of lymphohematopoietic elements. Surprisingly, in contrast to fully allogeneic chimeras reconstituted by allogeneic T lymphocyte-depleted BM, our stem cell chimeras were found to produce an impressive primary antibody response to the cellular antigen, sheep red blood cells. Thus, bone progenitor cells or osteoblasts may represent an essential component of the stromal cell population and facilitate engraftment of marrow stem cells in an allogeneic environment.
Effects of inhibitors of the activity of poly (ADP‐ribose) synthetase on the liver injury caused by ischaemia‐reperfusion: a comparison with radical scavengers (1998)

1. Poly (ADP-ribose) synthetase (PARS) is a nuclear enzyme activated by strand breaks in DNA which are caused by reactive oxygen species (ROS) and peroxynitrite. Excessive activation of PARS may contribute to the hepatocyte injury caused by ROS in vitro and inhibitors of PARS activity reduce the degree of reperfusion injury of the heart, skeletal muscle and brain in vivo. Here we compared the effects of various inhibitors of the activity of PARS with those of deferoxamine (an iron chelator which prevents the generation of hydroxyl radicals) and tiron (an intracellular scavenger of superoxide anion) on the degree of hepatic injury caused by ischaemia and reperfusion of the liver in the anaesthetized rat or rabbit. 2. In the rat, ischaemia (30 or 60 min) and reperfusion (120 min) of the liver resulted in significant increases in the serum levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) indicating the development of liver injury. Intravenous administration of the PARS inhibitors 3-aminobenzamide (3-AB, 10 mg kg(-1) or 30 mg kg(-1)), 1,5-dihydroxyisoquinoline (ISO, 1 mg kg(-1)) or 4-amino-1,8-naphthalimide (4-AN, 3 mg kg(-1)) before reperfusion did not reduce the degree of liver injury caused by ischaemia-reperfusion. 3. In contrast to the PARS inhibitors, deferoxamine (40 mg kg(-1)) or tiron (300 mg kg(-1)) significantly attenuated the rise in the serum levels of AST and ALT caused by ischaemia-reperfusion of the liver of the rat. 4. In the rabbit, the degree of liver injury caused by ischaemia (60 min) and reperfusion (120 min) was also not affected by 3-AB (10 mg kg(-1)) or ISO (1 mg kg(-1)). 5. These results support the view that the generation of oxygen-derived free radicals mediates the liver injury associated with reperfusion of the ischaemic liver by mechanism(s) which are independent of the activation of PARS.
Minor fishery for the Indian oil sardine (Sardinella longiceps)along Saurashtra coast (1991)

During October 1987 to March 1988 the total estimated oil sardine, Sardinella longiceps, landed by cast net at Poibander was about 1 300 tonnes with an average monthly landings of about 21S.9 tonnes. The length (L)-weight (W) relationships of male and female were W = 1.514 + 2,744 L and 4!237 + 2.617 L, respectively. The mean modal length increased from 75 mm in October - November to 155 mm in Febmary - March. The stage of maturity progressed from immature in October to maturing (stage IV) in March. Major landings of oil sardine in India are fiom the southwestcoast(Anthony Raja 1969, Anonymous \9M). FotedarandSavaria(1988) reported oil sardine landings along the Sau­ rashtra Cbast during November 1986 - Febru­ ary 1987. The present study was conducted to know whether the oil sardine occurs regularly along the Saurashtra coast.
Caesarean section for placenta praevia complicated by postpartum haemorrhage managed successfully with recombinant activated human coagulation Factor VIIa (2004)

"Caesarean section for placenta praevia complicated by postpartum haemorrhage managed successfully with recombinant activated human coagulation Factor VIIa." Journal of Obstetrics and Gynaecology, 24(8), pp. 925–926
Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms <i>TCF7L2</i> as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk (2006)

Recent data suggest that common variation in the transcription factor 7-like 2 (TCF7L2) gene is associated with type 2 diabetes. Evaluation of such associations in independent samples provides necessary replication and a robust assessment of effect size. Using four TCF7L2 single nucleotide polymorphisms (SNPs; including the two most associated in the previous study), we conducted a case-control study in 2,158 type 2 diabetic subjects and 2,574 control subjects and a family-based association analysis in 388 parent-offspring trios all from the U.K. All SNPs showed powerful associations with diabetes in the case-control analysis, with strongest effects at rs7903146 (allele-wise relative risk 1.36 [95% CI 1.24-1.48], P = 1.3 x 10(-11)). Data were consistent with a multiplicative model. The family-based analyses provided independent evidence for association at all loci (e.g., rs4506565, 62% transmission, P = 7 x 10(-5)) with no parent-of-origin effects. The frequency of diabetes-associated TCF7L2 genotypes was greater in cases ascertained for positive family history and early onset (rs4606565, P = 0.02); the population-attributable risk, estimated from the least-selected cases, is approximately 16%. The overall evidence for association for these variants (P = 4.4 x 10(-14) combining case-control and family-based analyses for rs4506565) exceeds genome-wide significance criteria and clearly establishes TCF7L2 as a type 2 diabetes susceptibility gene of substantial importance.
A hairpin‐loop conformation in tandem repeat sequence of the ice nucleation protein revealed by NMR spectroscopy (1997)

The 1H-NMR spectrum of a synthetic 24-residue peptide (A1-G-V-D-S-S-L-I-A-G-Y-G-S-T-Q-T-S-G-S-D-S-A-L-T24; INP24), comprising three repeats of the 8-residue consensus sequence of Pseudomonas syringae ice nucleation protein, was fully assigned using 2-dimensional (2D) NMR spectroscopy at 4 degrees C and 30 degrees C. Close proximity of the aliphatic protons between Leu7, Ile8, Ala9, and the ring-protons of Tyr11 was indicated from the observation of the inter-molecular nuclear Overhauser enhancement (NOE) effect. Hydrogen-bonding was strongly suggested for the NH group of Leu7 from its extremely low-temperature coefficient estimated from the temperature dependence of the chemical shift. These results indicate the formation of a hairpin-loop conformation constructed by a hexapeptide segment of INP24, -Leu7-Ile8-Ala9-Gly10-Tyr11-Gly12.
A European survey on awareness of post-surgical adhesions among gynaecological surgeons (2013)

The present survey was conducted among gynaecological surgeons from several European countries to assess the actual knowledge and practice related to post-surgical adhesions and measures for reduction. From September 1, 2012 to February 6, 2013, gynaecological surgeons were invited to answer an 18-item online questionnaire accessible through the ESGE website. This questionnaire contained eight questions on care settings and surgical practice and ten questions on adhesion formation and adhesion reduction. Four hundred fourteen surgeons participated; 70.8 % agreed that adhesions are a source of major morbidity. About half of them declared that adhesions represented an important part of their daily medical and surgical work. About two thirds informed their patients about the risk of adhesion. Most cited causes of adhesions were abdominal infections and extensive tissue trauma, and endometriosis and myomectomy surgery. Fewer surgeons expected adhesion formation after laparoscopy (18.9 %) than after laparotomy (40.8 %); 60 % knew the surgical techniques recommended to reduce adhesions; only 44.3 % used adhesion-reduction agents on a regular basis. This survey gives a broad picture of adhesion awareness amongst European gynaecological surgeons, mainly from Germany and the UK. The participants had a good knowledge of factors causing adhesions. Knowledge of surgical techniques recommended and use of anti-adhesion agents developed to reduce adhesions need to be improved.
Group Handover among Heterogeneous Wireless Networks (2006)

In the past few years, significant work has been done towards inter-operation of heterogeneous networks such as WLAN, UMTS and DVB. Most work so far has aimed to provide an integration of these networks rather than their co-operation. In the mobile VCE III program, heterogeneous networks remain autonomous, independently-managed entities. In other words, networks are inter-worked and cooperate with each other to provide enriched services to users. The networks are owned by and under the control of their respective operators. The access cores of these networks are inter-connected via a logical interface enabling inter-working at the network and service layers. As part of the mobile VCE Core III program, we focus on mobility management, which is the key issue to support seamless roaming of the mobile users among these heterogeneous networks in an efficient way. In this paper, we consider a group handover scenario from a WLAN to DVB/UMTS network within the network mobility (NEMO) framework
Peer-to-peer technology for interconnecting web services in heterogeneous networks (2004)

The interconnection of software components is a key to enabling collaborative work. However, technology differences and security barriers like firewalls often hinder establishing collaborative infrastructures between enterprises or even within a single enterprise. We introduce a peer-to-peer based network infrastructure that transparently overcomes these problems using relay and routing mechanisms as well as different underlying transport protocols. We discuss the application of this technology to interconnect Web services.
Applications of linear induction motors in industry (1971)

Numerous papers have been published in the Proceedings IEE on theoretical aspects of linear-induction-motor design. There are now large numbers of these motors used in practical applications, and the paper describes many of these. Four basic types of linear induction motor are currently in use: single sided, double sided, disc and tubular, using 3-phase or single-phase supplies. These types and their speed-control gear are dealt with in the paper.
High Performance MOS Tunneling Cathode with CoSi2 Gate Electrode (2000)

The high performance of metal-oxide-semiconductor (MOS) tunneling cathodes with CoSi2 gates was demonstrated. First, the deposition process of CoSi2 was optimized. Stoichiometric CoSi2 films were formed by codeposition with Co and Si. The electrical measurement suggested that deposition above 300°C was necessary to obtain low-resistivity silicide films. Second, operation characteristics were evaluated for MOS tunneling cathodes with CoSi2 gates formed at 400°C. The emission efficiency increased with decreasing gate thickness and became as high as 1.5 ×10-3 for the 5 nm CoSi2 cathode. The efficiency did not depend on the electric field above 8.5 MV cm-1. Thus, the CoSi2 gates were deemed suitable for operation at higher electric fields to obtain larger emission currents. The lifetime of the cathodes corresponded to 500 h for operation at 8.5 MV cm-1.
Searching for Better Plasmonic Materials (2009)

Plasmonics is a research area merging the fields of optics and nanoelectronics by confining light with relatively large free-space wavelength to the nanometer scale - thereby enabling a family of novel devices. Current plasmonic devices at telecommunication and optical frequencies face significant challenges due to losses encountered in the constituent plasmonic materials. These large losses seriously limit the practicality of these metals for many novel applications. This paper provides an overview of alternative plasmonic materials along with motivation for each material choice and important aspects of fabrication. A comparative study of various materials including metals, metal alloys and heavily doped semiconductors is presented. The performance of each material is evaluated based on quality factors defined for each class of plasmonic devices. Most importantly, this paper outlines an approach for realizing optimal plasmonic material properties for specific frequencies and applications, thereby providing a reference for those searching for better plasmonic materials.
Sunscreens Cause Coral Bleaching by Promoting Viral Infections (2008)

We conclude that sunscreens, by promoting viral infection, potentially play an important role in coral bleaching in areas prone to high levels of recreational use by humans.
Interventions for hand eczema (2002)

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of interventions for hand eczema.
Inactivation of proteins by irradiation of gold nanoparticles with nano- and picosecond laser pulses (2003)

Irradiation of 15 nm gold particles with nano- and picosecond laser pulses can create locally temperatures beyond the critical point of water. Due to the short heating times the temperature is localised to the vicinity of the particles. Under irradiation with nano- and picosecond pulses an inactivation of the enzymes alkaline phosphatase and chymotrypsin which were bound to the surface of the particles was observed. As expected by strong temperature gradient caused by the short irradiation time the protein inactivation is localized within a few tens of nanometers when picosecond pulses were used. This was shown by irradiating gold protein conjugates in which the protein was bound via two anitbodies to the particle.
Structure Function Analysis of an ADP-ribosyltransferase Type III Effector and Its RNA-binding Target in Plant Immunity (2011)

The Pseudomonas syringae type III effector HopU1 is a mono-ADP-ribosyltransferase that is injected into plant cells by the type III protein secretion system. Inside the plant cell it suppresses immunity by modifying RNA-binding proteins including the glycine-rich RNA-binding protein GRP7. The crystal structure of HopU1 at 2.7-Å resolution reveals two unique protruding loops, L1 and L4, not found in other mono-ADP-ribosyltransferases. Site-directed mutagenesis demonstrates that these loops are essential for substrate recognition and enzymatic activity. HopU1 ADP-ribosylates the conserved arginine 49 of GRP7, and this reduces the ability of GRP7 to bind RNA in vitro. In vivo, expression of GRP7 with Arg-49 replaced with lysine does not complement the reduced immune responses of the Arabidopsis thaliana grp7-1 mutant demonstrating the importance of this residue for GRP7 function. These data provide mechanistic details how HopU1 recognizes this novel type of substrate and highlights the role of GRP7 in plant immunity.
A Convenient and Versatile Route to Hydroquinolines by Inter- and Intramolecular Aza-Diels-Alder Pathways (1999)

Surprisingly, the simplest method possible for o-azaxylylene production, base-induced elimination of hydrogen chloride from amide or sulfonamide derivatives of o-(chloromethyl)aniline, has never been reported. This powerful approach provides easy and stereoselective access to polycyclic hydroquinolines, as shown for an example in Equation (1).