gebhart/patrepeval huggingface dataset:
Angle of Arrival Estimation using Received Signal Strength with Directional Antennas (2007)

This paper presents experimental results of angle of arrival (AOA) estimation for sensor node localization of wireless networks via received signal strength measurements from directional antennas. Field experiments were conduct with a Hex Dipole Parasitic Antenna (HDPA) board using an IEEE 802.11 2.4 GHz radio. A number of beam patterns of the HDPA are measured and stored as data sets organized by time and distance. The AOA estimates had large error for a single training data set; however when multiple data sets taken over longer time periods were averaged together the AOA error decreased. Intelligently choosing directional beam patterns is shown to improve the AOA performance while lowering complexity.\nAdvisor: Lee Potter
Survival of fetal porcine pancreatic islet tissue transplanted to a diabetic patient: Findings by ultrastructural immunocytochemistry (1998)

Porcine fetal endocrine pancreatic tissue was placed under the kidney capsule in a diabetic renal transplant patient. In a core-needle kidney biopsy specimen obtained 3 weeks after transplantation, clusters of epithelial cells were identified in the subcapsular space. The ultrastructural and immunocytochemical features of these cells were typical of pancreatic islet cells. Some cells stained positively for insulin; others stained positively for glucagon, somatostatin or chromagranin A. There were well-defined cytoplastic storage and transport granulae that indicated hormone synthesis. The ultrastructural findings provide further evidence that porcine cells can survive after transplantation to humans.
Ex Vivo Modeling of Oral HIV Transmission in Human Palatine Tonsil (2005)

The majority of newly acquired HIV infections are believed to occur following transmission of virus infectivity across mucosal surfaces, although many mechanistic details still remain unresolved. We have used human ex vivo organ cultures and primary cell populations to analyze the cellular and molecular basis for mucosal HIV transmission. By using human palatine tonsil from routine tonsillectomies and semen from HIV-positive donors, we have created an experimental equivalent to oral HIV transmission. HIV infection was readily transferred into tonsillar lymphocytes, but this transmission into lymphocytes was dramatically reduced when the exposed lymphocyte populations were protected by intact mucosal surfaces. In this study, we consider the impact that leukocyte activation and morphological aberrations in surface structure may have on susceptibility to primary HIV infection and introduce novel time-lapse confocal microscopy procedures that begin to reveal the dynamic complexity associated with cell-mediated HIV transmission.
MIMO Signal Multiplexing and Detection Based on Compressive Sensing and Deep Learning (2019)

We propose a novel signal multiplexing and detection method for multiple-input multiple-output (MIMO) communication systems, especially when the number of transmitting and receiving antennas is limited. Inspired by the idea of Compressive Sensing (CS) which can recover a given signal vector from a vector of measurements with less dimensions, our proposed CS-based multiplexing scheme can deliver a modulated data vector with length l via a MIMO system with fewer transmitting/receiving antennas than l , offering higher multiplexing gain. On the receiving side, our proposed detection scheme has two steps, which resort the BCS algorithm and a Deep-Learning algorithm to recover the original modulated data vector. Analytical and simulation results show that the proposed multiplexing and detection method can achieve larger multiplexing gain while reserving good bit error rate (BER), offering a novel research paradigm to improve the utility rate of multiple antennas.
The conceptual basis for mediation services (1997)

As information systems grow, they depend increasingly on diverse, heterogeneous resources, such as databases, knowledge bases, bibliographic files, Web-based information, computational facilities, digital libraries, geographic information systems, and simulations. Users typically develop and maintain these resources autonomously. Mediator modules comprise a layer of intelligent middleware services in information systems that link data resources and application programs. Currently, system developers must build intelligent mediators by carefully acquiring domain knowledge and handcrafting the required code. This article presents the conceptual underpinning for automating mediation.
Should Low Molecular Weight PSMA Targeted Ligands Get Bigger and Use Albumin Ligands for PSMA Targeting? (2017)

Prostate Specific Membrane Antigen (PSMA) is strongly expressed in prostate cancer. Recently a number of low-molecular-weight inhibitors have demonstrated excellent PSMA targeting activity for both imaging as well as Lutecium-177 radiotherapy in human trials. The paper by Choy et al raises the question of whether we can further increase the effectiveness of PSMA targeted therapy by adding an albumin-binding entity to low-molecular-weight agents.
Semantic brokering over dynamic heterogeneous data sources in InfoSleuth/sup TM/ (1999)

InfoSleuth is an agent based system for information discovery and retrieval in a dynamic, open environment. The paper discusses InfoSleuth's multi broker design and implementation. InfoSleuth's brokering function combines reasoning over both the syntax and semantics of agents in the domain. The broker must reason over explicitly advertised information about agent capabilities to determine which agent can best provide the requested services. Brokering in InfoSleuth is a match making process, recommending agents that provide services to agents requesting services. Robustness and scalability issues dictate that brokering must be distributable across collaborating processes. Our multibroker design is a peer-to-peer system that requires brokers to advertise to and receive advertisements from other brokers. Brokers collaborate during match making to give a collective response to requests initiated by non broker agents. This results in a robust, scalable brokering system.
Robotic Harvesting System for Eggplants (2002)

The harvesting operation for eggplants is complicated and accounts for a little less than 40% of the total number of working hours. For automating the harvesting operation, an intelligent robot that can emulate the judgment of human labor is necessary. This study was conducted with a view to developing a robotic harvesting system that performs recognition, approach, and picking tasks. In order to accomplish these tasks, 3 essential components were developed. First, a machine vision algorithm combining a color segment operation and a vertical dividing operation was developed. The algorithm could detect the fruit even under different light conditions. Next, a visual feedback fuzzy control model to actuate a manipulator was designed. The control model enabled the manipulator end to approach the fruit from a distance of 300 mm. Furthermore, an end-effector composed of a fruit-grasping mechanism, a size-judging mechanism, and a peduncle-cutting mechanism was developed. It produced enough force for grasping the fruit and cutting the tough peduncle. Finally, the 3 essential components were functionally combined, and a basic harvesting experiment was conducted in the laboratory to evaluate the performance of the system. The system showed a successful harvesting rate of 62.5%, although the end-effector cut the peduncle at a slightly higher position from the fruit base. The execution time for harvesting of an eggplant was 64.1 s.
Measurements of secondary neutron dose from 15 MV and 18 MV IMRT (2005)

Secondary neutron dose-equivalents were determined for conventional and intensity modulated radiation therapy (IMRT) prostate treatments for 15 and 18 MV X-ray beams. Conventional and IMRT treatment plans were generated to deliver 45 Gy to the prostate, seminal vessicles and external and internal iliac lymph nodes. Neutron spectra were determined by unfolding measurements from a TLD-based Bonner sphere system. Treatments using 18 MV IMRT and conventional plans result in neutron ambient dose-equivalents of 687 and 112 mSv, respectively. Delivery of the 15 MV IMRT and conventional plans results in neutron ambient dose-equivalents of 327 and 52 mSv, respectively. The data illustrate that using lower photon energies for IMRT reduces the secondary neutron dose, while still achieving comparable treatment volume coverage and sparing critical normal tissue.
Crosstalk Noise Control in an SoC Physical Design Flow (2004)

Signal integrity closure is one of the key challenges in deep submicron physical design. In this paper, we propose a physical design methodology which includes signal integrity management through crosstalk noise analysis and repair at multiple phases of the design so that a quick noise convergence can be achieved. The methodology addresses both functional and delay noise problems in the design and is targeted for block-, platform-, and chip-level physical design of system-on-chip designs. A number of case studies are presented to illustrate the effectiveness of the proposed methodology and to provide valuable insights useful for successful signal integrity management.
Erlotinib Attenuates Homologous Recombinational Repair of Chromosomal Breaks in Human Breast Cancer Cells (2008)

The epidermal growth factor receptor (EGFR) family has been implicated in several cancers, including breast, and its members have become the target of novel cancer therapies. In this report, we show a novel link between erlotinib, a potent EGFR inhibitor, DNA damage, and homology-directed recombinational repair (HDR) in human breast cancer cells. Erlotinib suppresses HDR. This is not secondary to erlotinib-mediated changes in cell cycle and is associated with increased gamma-H2AX foci, which is an in situ marker of chromosomal double-strand breaks. Both Rad51 and BRCA1 are essential components of the HDR machinery. Consistent with decreased HDR in erlotinib-treated cells, erlotinib also attenuates DNA damage-induced Rad51 foci and results in cytoplasmic retention of BRCA1. As BRCA1 is a shuttling protein and its nuclear function of promoting HDR is controlled by its subcellular localization, we further show that targeted translocation of BRCA1 to the cytoplasm enhances erlotinib sensitivity. These findings suggest a novel mechanism of action of erlotinib through its effects on the BRCA1/HDR pathway. Furthermore, BRCA1/HDR status may be an innovative avenue to enhance the sensitivity of cancer cells to erlotinib.
Oxidation Chemistry of Norepinephrine: Partitioning of the <i>O</i>-Quinone between Competing Cyclization and Chain Breakdown Pathways and Their Roles in Melanin Formation (2007)

Aberrant oxidation of norepinephrine (1) via the transient o-quinone has been implicated as a critical pathogenetic mechanism underlying the degeneration of noradrenergic cell bodies in the locus coeruleus in Parkinson's disease, the degeneration of noradrenergic nerve terminals in Alzheimer's disease and following transient cerebral ischemia, and the onset and progression of idiopathic vitiligo. An oxidative pathway of 1 is also believed to account for the slow deposition of neuromelanin in pigmented neurons of the locus coeruleus. Remarkably, after extensive investigations spanning over several decades, there is still a lack of knowledge of the oxidation chemistry of 1 beyond the classic cyclization route leading to aminochrome and lutin intermediates. We report herein that oxidation of 1 in the 50-500 microM concentration range with H2O2-dependent oxidizing agents, such as the Fenton reagent (Fe2+-EDTA/H2O2) and the horseradish peroxidase (HRP)/H2O2 system, leads not only to the known cyclization products, such as noradrenochrome and 5,6-dihydroxyindole (3), but also to a significant proportion of chain breakdown products, including 3,4-dihydroxybenzaldehyde, 3,4-dihydroxybenzoic acid, 3,4-dihydroxymandelic acid, and 3,4-dihydroxyphenylglyoxylic acid, which has never been described among the oxidation products or metabolites of 1. Analysis of the brown melanin-like pigment obtained by oxidation of 1 with HRP/H2O2 gave pyrrole-2,3-dicarboxylic acid and pyrrole-2,3,5-tricarboxylic acid, diagnostic markers of 3-derived units in eumelanins. Comparison with reference pigments prepared by similar oxidation of dopamine and 3 indicated that in the case of 1 oxidative polymerization of indole units through the 2-position contributes only to a minor extent to melanin formation. Overall, the results of this study provide a complete characterization of the oxidative chain fission pathways of 1, highlight 3,4-dihydroxyphenylglyoxylic acid as a novel possible metabolic product of this catecholamine, and yield an insight into norepinephrine-melanin, a putative component of locus coeruleus neuromelanin.
A novel graph algorithm for circuit recognition (2002)

This paper presents novel subcircuit recognition and verification algorithms based on a new technique for circuit graph coding. This coding uniquely identifies each subcircuit and is ideal for applications requiring circuit graph isomorphism in the presence of parasitics. These algorithms use a new circuit graph and graph isomorphism techniques to generate a unique code for each subcircuit, which has led to an improved circuit recognition algorithm.
The Role of Eucaryotic Elongation Factor Tu in Protein Synthesis (1980)

A sensitive radioimmunoassay for eucaryotic elongation factor Tu (eEF-TU) was developed using radioiodinated elongation factor T (eEF-T) and goat anti-(rabbit eEF-T) immunoglobulins coupled to a solid support. eEF-T was iodinated with 125I to a specific activity of 7 x 10(3) counts min-1 ng-1 using a system employing lactoperoxidase and glucose oxidase coupled to a solid support. The assay exhibits a limit of detection of about 1 ng eEF-TU and an intraassay variability of < 10%. By using the radioimmunoassay, it was found that eEF-Tu is a major non-hemoglobin protein of rabbit reticulocyte postribosomal supernatant proteins, comprising about 3% of the total hemoglobin and 10--13% of the non-hemoglobin proteins. Similar results were found for a number of different tissues and cells, including rabbit heart, brain, liver and kidneys, as well as both induced and non induced Friend erythroleukemia cells. Values of eEF-Tu ranged from 1% of supernatant proteins in heart to about 11% in noninduced erythroleukemic cells. The levels of eEF-Tu in these mammalian tissues were comparable to the level of the homologous factor EF-Tu in Escherichia coli. It has previously been found that EF-Tu constitutes about 6--8% of the supernatant proteins of E. coli [Furano, A. V. (1975) Proc. Natl Acad. Sci. USA, 72, 4780--4784]. The level of eEF-Tu in reticulocytes was compared to the abundance of other components of protein synthesis in reticulocytes, such as translocase (eEF-G), tRNA, ribosomes and eIF-2. In all cases eEF-Tu was present in large excess over these other components.
On Hash-Based Work Distribution Methods for Parallel Best-First Search (2017)

Parallel best-first search algorithms such as Hash Distributed A* (HDA*) distribute work among the processes using a global hash function. We analyze the search and communication overheads of state-of-the-art hash-based parallel best-first search algorithms, and show that although Zobrist hashing, the standard hash function used by HDA*, achieves good load balance for many domains, it incurs significant communication overhead since almost all generated nodes are transferred to a different processor than their parents. We propose Abstract Zobrist hashing, a new work distribution method for parallel search which, instead of computing a hash value based on the raw features of a state, uses a feature projection function to generate a set of abstract features which results in a higher locality, resulting in reduced communications overhead. We show that Abstract Zobrist hashing outperforms previous methods on search domains using hand-coded, domain specific feature projection functions. We then propose GRAZHDA*, a graph-partitioning based approach to automatically generating feature projection functions. GRAZHDA* seeks to approximate the partitioning of the actual search space graph by partitioning the domain transition graph, an abstraction of the state space graph. We show that GRAZHDA* outperforms previous methods on domain-independent planning.
Amelioration of oxidative stress in red blood cells from patients with β‐thalassemia major and intermedia and E‐β‐thalassemia following administration of a fermented papaya preparation (2010)

In beta-hemoglobinopathies, such as beta-thalassemia (thal) and sickle cell anemia, the primary defects are mutations in the beta-globin gene. However, many aspects of the pathophysiology are mediated by oxidative stress. Fermented papaya preparation (FPP), a natural health food product obtained by biofermentation of carica papaya, has been shown to limit oxidative stress both in vitro and in vivo. We studied the effect of FPP on two groups of beta-thal patients: beta-thal, major and intermedia, (in Israel) and E-beta-thal (in Singapore). The results indicated that in both groups FPP treatment increased the content of reduced glutathione (GSH) in red blood cells (RBC), and decreased their reactive oxygen species (ROS) generation, membrane lipid peroxidation, and externalization of phosphatidylserine (PS), indicating amelioration of their oxidative status, without a significant change in the hematological parameters. Since the turnover of the erythron is relatively slow, it is possible that longer duration of treatment, probably with the addition of an iron chelator, is required in order to achieve the latter goals.
Liraglutide ameliorates non‐alcoholic fatty liver disease by enhancing mitochondrial architecture and promoting autophagy through the SIRT1/SIRT3–FOXO3a pathway (2015)

Liraglutide diminishes oxidative stress by enhancing mitochondrial architecture and promoting autophagy through the SIRT1/SIRT3-FOXO3a-LC3 pathway to ameliorate diet-induced NAFLD.
2007 Journal of Urology Consultants (2008)

No AccessJournal of Urology2007 Journal of Urology Consultant1 Jun 20082007 Journal of Urology Consultants William D. Steers William D. SteersWilliam D. Steers More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2008.03.129AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 6June 2008Page: 2494-2500 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information William D. Steers More articles by this author Expand All Advertisement PDF downloadLoading ...
Sodium Lauryl Sulfate Profile (2018)

NYS IPM Type: Minimum Risk Pesticide
Marble game with optimal ferroelectric switching (2014)

A low coercivity and, consequently, low hysteresis loss are desired properties for ferroelectric materials used in high-power and high-frequency actuators. The coercive field required for the onset of ferroelectric switching is shown to develop a strong directional anisotropy due to peculiarities of an energy surface associated with the polarization rotation. It is found that the ferroelectric anisotropy exhibits 'hard' and 'easy' switching axes similar to magnetic materials. The hard axis corresponds to 180° polarization reversal, whereas the easy axis favors 90° switching. Our results suggest that the intrinsic low coercivity and the full polarization reversal may not be achieved at the same time under uniaxial excitation. A rotating electric field excitation is proposed in order to circumvent this limitation and to guide the polarization switching along a curved path.
Adaptive transmit power control based on signal strength and frame loss measurements for WLANs (2009)

In the past few years, we witnessed a rapid penetration of Wireless Local Area Networks (WLANs) into the home and enterprise. Emerging technology such as the IEEE 802.11n radio, which is getting increasingly aﬀordable, makes delivering multimedia content overwireless networks possible and this would drive the technology further into our daily life. As the number of available wireless channels in the unlicensed spectrum is limited (3 non-overlapping channels in 2.4GHz unlicensed band and up to 24 non-overlapping channels in 5GHz unlicensed band), they have to be shared by multiple WLANs consisting of Access Points (APs) and STAtions (STAs). In a Multi-Dwelling Unit (MDU) WLAN deployment, e.g. in an apartment building or hotel, transmissions in overlapping cells tend to interfere with each other. This will adversely impact the aggregate wireless network throughput and thus the quality of experience for applications such as multimedia streaming. Hence there is a need for automatic and adaptive resource management strategy to ensure a good overall network performance.In this thesis we propose an adaptive per-link Transmit Power Control (TPC) solution for WLANs. TPC can reduce interference, increase channel reuse, and eventually increase the overall capacity in dense 802.11 wireless networks. However intelligent algorithms arerequired to adapt transmit power in a practical and distributed way to achieve improvement in performance. It becomes more challenging given diﬀerent types of interference (cooperative and non-cooperative) in the unlicensed band as well as the hidden node problem. From a detailed study of the previous eﬀorts at power control, we observe that in order to make better decisions on transmit power; an AP needs to actively monitor several factors. Hence we develop a TPC algorithm based on both link margin estimation as well as frame loss rate measurement. Compared to previous solutions that adapt the transmit power based on measurement of a single parameter (either received signal strength or frame loss rate), the proposed power control mechanism can diagnose and take remedial action for hidden nodes and channel access asymmetry problems manifesting as frame losses. It is adaptive to mobility, complementary to any rate control algorithm and can also be incrementally deployed amidst non-cooperative nodes. We have implemented the algorithm as an application running on Atheros chipset-based 802.11n APs, taking practical system-level limitations into account. The proposed solution achieves signiﬁcant transmit power reduction at the APs (to as low as 60% of the maximum power) for STAs as far as 70ft and over ∼60% increase in total network throughput through interference mitigation.
A Diamagnetic Trap with 1D Camelback Potential (2014)

The ability to trap matter is of great importance in experimental physics since it allows isolation and measurement of intrinsic properties of the trapped matter. We present a study of a three dimensional (3D) trap for a diamagnetic rod in a pair of diametric cylindrical magnets. This system yields a fascinating 1D camelback potential along the longitudinal axis which is one of the elementary model potentials of interest in physics. This potential can be tailored by controlling the magnet length/radius aspect ratio. We developed theoretical models and verify them with experiments using graphite rods. We show that, in general, a camelback field or potential profile exists in between a pair of parallel linear dipole distribution. By exploiting this potential, we demonstrate a unique and simple technique to determine the magnetic susceptibility of the rod. This system could be further utilized as a platform for custom-designed 1D potential, a highly sensitive force-distance transducer or a trap for semiconductor nanowires.