gebhart/patrepeval huggingface dataset:
Managing acute cough in children: evidence-based guidelines. (2008)

This article examines the evidence-based guidelines for diagnosis and treatment of acute cough in children. Cough is a common symptom in children and a frequent reason for consultation in primary care. Generally, an acute cough is a self-limiting condition resulting from expected childhood viral illnesses. However, a child should be thoroughly evaluated to rule out a serious underlying condition or disease responsible for the cough. Parents are often concerned and anxious about their child's cough. The use of over-the-counter cough and cold medications is widespread and parents commonly request primary care providers to provide prescriptions to alleviate cough symptoms. The American College of Chest Physicians has recommended clinical practice guidelines based on the conclusion of systematic reviews. These reviews indicate that cough medications offer no symptomatic relief for acute cough in children, and the use of cough and cold medications is inappropriate in young children and also places young children at risk for potential side effects and adverse reactions. The management of acute cough in children is based on a "wait, watch, review" approach. Clinicians should educate parents on expected illness duration, the risks of using over-the-counter medications, and discuss safe, supportive care measures to alleviate the child's discomfort.
Automated and distributed protocol testing and debugging for wireless ad-hoc networks (2011)

poster Automated and distributed protocol testing and debugging for wireless ad-hoc networks Share on Authors: Xiaoshuang Wang Binghamton University, Binghamton, NY, USA Binghamton University, Binghamton, NY, USAView Profile , Vaibhav Nipunage Binghamton University, Binghamton, NY, USA Binghamton University, Binghamton, NY, USAView Profile , Umesh Deshpande Binghamton University, Binghamton, NY, USA Binghamton University, Binghamton, NY, USAView Profile , Kartik Gopalan Binghamton University, Binghamton, NY, USA Binghamton University, Binghamton, NY, USAView Profile Authors Info & Claims MobiWac '11: Proceedings of the 9th ACM international symposium on Mobility management and wireless accessOctober 2011 Pages 183–186https://doi.org/10.1145/2069131.2069166Online:31 October 2011Publication History 0citation99DownloadsMetricsTotal Citations0Total Downloads99Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Selective Sputtering and Atomic Resolution Imaging of Atomically Thin Boron Nitride Membranes (2009)

We report on the preparation, atomic resolution imaging, and element selective damage mechanism in atomically thin boron nitride membranes. Flakes of less than 10 layers are prepared by mechanical cleavage and are thinned down to single layers in a high-energy electron beam. At our beam energies, we observe a highly selective sputtering of only one of the elements and predominantly at the exit surface of the specimen, and then subsequent removal of atoms next to a defect. Triangle-shaped holes appear in accordance with the crystallographic orientation of each layer. Defects are compared to those observed in graphene membranes. The observation of clean single-layer membranes shows that hexagonal boron nitride is a further material (in addition to graphene) that can exist in a quasi-two-dimensional allotrope without the need for a substrate.
The Finger Domain of the Human Deubiquitinating Enzyme HAUSP is a Zinc Ribbon (2004)

Human deubiquitinating enzyme HAUSP is a cysteine protease that regulates the levels of the tumor suppressor protein p53. By comparative sequence and structural analysis, we show that the previously uncharacterized finger domain insert to the catalytic core of HAUSP is a zinc ribbon that has lost its zinc-binding ability.
Fuzzy edge detection based on pixel's gradient and standard deviation values (2009)

This paper presents a new fuzzy based edge detection algorithm. Each different edge detection method has its own advantages and disadvantages. For example each method detects part of real edges and also some unreal edges. To reduce this effect we have used two different source of information and a fuzzy system to decide about whether each pixel is edge or not. First both gradient and standard deviation values are computed, form two set of edges, utilized as inputs for our fuzzy system. Then fuzzy system decides on each pixel according to fuzzy rules. Finally we have compared results of the proposed algorithm with other algorithms such as Sobel, Robert, and Prewitt. Experimental results show the ability and high performance of proposed algorithm.
Automatic Generation of 3D Statistical Shape Models with Optimal Landmark Distributions (2007)

The distribution of landmarks on the training shapes is -- beyond the correspondence issue -- a crucial point in model construction.
Boron hydride derivatives for neutron capture therapy. Antibody approach (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBoron hydride derivatives for neutron capture therapy. Antibody approachHou S. Wong, Eugene I. Tolpin, and William N. LipscombCite this: J. Med. Chem. 1974, 17, 8, 785–791Publication Date (Print):August 1, 1974Publication History Published online1 May 2002Published inissue 1 August 1974https://pubs.acs.org/doi/10.1021/jm00254a001https://doi.org/10.1021/jm00254a001research-articleACS PublicationsRequest reuse permissionsArticle Views182Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Liver Sinusoidal Endothelial Cells Tolerize T Cells across MHC Barriers in Mice (2005)

Although livers transplanted across MHC barriers in mice are normally accepted without recipient immune suppression, the underlying mechanisms remain to be clarified. To identify the cell type that contributes to induction of such a tolerance state, we established a mixed hepatic constituent cell-lymphocyte reaction (MHLR) assay. Irradiated C57BL/6 (B6) or BALB/c mouse hepatic constituent cells (HCs) and CFSE-labeled B6 splenocytes were cocultured. In allogeneic MHLR, whole HCs did not promote T cell proliferation. When liver sinusoidal endothelial cells (LSECs) were depleted from HC stimulators, allogeneic MHLR resulted in marked proliferation of reactive CD4(+) and CD8(+) T cells. To test the tolerizing capacity of the LSECs toward alloreactive T cells, B6 splenocytes that had transmigrated through monolayers of B6, BALB/c, or SJL/j LSECs were restimulated with irradiated BALB/c splenocytes. Nonresponsiveness of T cells that had transmigrated through allogeneic BALB/c LSECs and marked proliferation of T cells transmigrated through syngeneic B6 or third-party SJL/j LSECs were observed after the restimulation. Transmigration across the Fas ligand-deficient BALB/c LSECs failed to render CD4(+) T cells tolerant. Thus, we demonstrate that Fas ligand expressed on naive LSECs can impart tolerogenic potential upon alloantigen recognition via the direct pathway. This presents a novel relevant mechanism of liver allograft tolerance. In conclusion, LSECs are capable of regulating a polyclonal population of T cells with direct allospecificity, and the Fas/Fas ligand pathway is involved in such LSEC-mediated T cell regulation.
Concentration Correlation Spectroscopy: A New Biophysical Probe Based on Occupation Number Fluctuations (1975)

Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More
Hyponatremia and Arginine Vasopressin Dysregulation: Mechanisms, Clinical Consequences, and Management (2006)

Hyponatremia, the most common electrolyte disorder, occurs frequently in older people and in hospitalized patients. Physiological changes of aging that interact with diseases and drugs commonly present in older people put this population at greater risk for hyponatremia. It can accompany central nervous system disorders, pulmonary and renal disease, cancer, congestive heart failure, and liver cirrhosis, as well as many commonly used drugs. Delayed recognition can lead to symptomatic hyponatremia with consequent cerebral edema and possibly irreversible neurological damage. Symptoms and signs of hyponatremia may be subtle or not attributed to hyponatremia. Most cases are of the euvolemic type, in which extracellular fluid volume is normal and is often due to the syndrome of inappropriate secretion of antidiuretic hormone. Hyponatremia can also occur in association with hypervolemia or hypovolemia. Common to all of these circumstances is increased secretion of arginine vasopressin (AVP). Understanding of the pathophysiological basis of hyponatremia and of brain compensatory mechanisms is critical to safe treatment. Fluid restriction or infusion of hypertonic saline can improve symptoms and normalize serum sodium levels but does not address excess AVP, which in most cases is the underlying cause of the disorder. A major new approach to treatment of hyponatremia is the development of aquaretics: AVP-receptor antagonists that provide a targeted therapeutic approach to correcting the many kinds of hyponatremia caused by excess AVP levels.
Alternate Molecular Layers of Metal Oxides and Hydroxyl Polymers Prepared by the Surface Sol-Gel Process (1998)

Extension of the surface sol-gel process to form molecularly alternate metal oxide/polymer films is reported. The Figure is a schematic illustration of the chemical structure of TiO2/poly(acrylic acid) multilayers grown using this method. It is demonstrated that films can also be assembled using aluminum, zirconium, niobium, and barium titanium alkoxides.
Type I and Type II Pathways of Fas-mediated Apoptosis Are Differentially Controlled by XIAP (2009)

The mechanism by which Fas activates the apoptotic pathway differs in so-called type I and type II cells. X chromosome-linked inhibitor of apoptosis protein has now been revealed as an important molecule that is differentially regulated in type I vs. type II cells.
Contributions to the geology of uranium and thorium by the United States Geological Survey and Atomic Energy Commission for the United Nations International Conference on Peaceful Uses of Atomic Energy, Geneva, Switzerland, 1955 (1956)

Within the boundaries of the United States abnormal amounts of uranium have been found in rocks of nearly all geologic ages and lithologic types. Distribution of ore is more restricted. On the Colorado Plateau, the Morrison formation of Jurassic age yields 61.4 percent of the ore produced in the United States, and the Chinle conglomerate and Shinarump formation of Triassic age contribute 26.0 and 5.8 percent, respectively. Clastic, carbonaceous, and carbonate sedimentary rocks of Tertiary, Mesozoic, and Paleozoic ages and veins of Tertiary age are the source of the remaining 6.8 percent.
Universal Real-Time PCR-Based Assay for Lentiviral Titration (2014)

Lentiviral vectors are efficient vehicles for stable gene transfer in both dividing and non-dividing cells. This feature among others makes lentiviral vectors a powerful tool in molecular research. However, the use of lentiviruses in research studies and clinical trials requires a precise and validated titration method. In this study, we describe a qPCR-based approach for estimation of lentiviral vector titer (pLV-THM-GFP). The use of WPRE (Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element) and albumin genes as templates for an SYBR green-based real-time qPCR method allows for a rapid, sensitive, reproducible, and accurate assessment of lentiviral copy number at an integrated lentiviral DNA level. Furthermore, this optimization enables measurement of lentiviral concentration even in very poor quality and small quantity material. Consequently, this approach provides researchers with a tool to perform low-cost assessment with highly repeatable results.
New Aluminum Lithium Alloys for Aerospace Applications (2007)

This paper discusses two aluminum-lithium alloys for aerospace applications, 2099 and 2199, including the relationship between their alloying elements and thermal-mechanical processing, to the alloy’s properties. The paper also includes selected properties of these alloys in sheet, plate and extrusion forms. Finally, a trade study conducted between Alcoa and Bombardier using these alloys is discussed which highlights the weight and performance benefits to an aircraft when alloys with optimized properties are selected for specific aircraft applications.
Evaluation Method Applying Fourier Transform Analysis for Conditioned Polishing Pad Surface Topography (2011)

The Fourier transform analysis is proposed to quantitatively evaluate the 3D surface topography of Chemical Mechanical Polishing (CMP) pads used for flattening and smoothing processed semiconductor substrates. The conditioned polishing pad surfaces have a wide range of irregular topographies ranging from topographies of a sub-micrometer to those of a hundredmicrometer order. Hence, a Confocal Laser Scanning Microscope (CLSM), which can provide nanometer resolution in wide range of lateral directions by means of linear encoded mechanical stage translation, was employed to obtain numerical data of the three-dimensional topographic surfaces of polishing pad samples. The measured topographic surfaces were analyzed using the spatial Fourier transform. We discuss the power spectrum in the spatial wavelengths of polishing pad surfaces which were conditioned with diamond grits of various shapes. The analyzed power spectra indicated that the surface topography characteristics varied with differently shaped diamond grits of the same size. The diamond grits roughened the polishing pad surface. We also found that a rough polishing pad surface, one that was roughed in a spatial wavelength that of less than 20 micrometers, removed more material than comparatively smooth pad surfaces.
A Study of Post-Orchiectomy Surveillance in Stage I Testicular Seminoma (1989)

A study of post-orchiectomy surveillance without radiation therapy was done in patients with histologically pure seminoma apparently confined to the testicle. Criteria for study entry included a negative physical examination, chest x-ray, bipedal lymphogram, excretory urogram, abdomino-pelvic computerized tomography scan and serum alpha-fetoprotein. Followup consisted of frequent clinical examination, repeat lymphograms, abdominal computerized tomography scans, chest x-rays and serum markers. The purpose of this study was to determine the percentage of patients cured by orchiectomy alone, percentage who ultimately required therapy for occult metastases beyond the testicle, sites of relapse, factors predictive of relapse, and over-all cure rate and treatment morbidity. Of 81 patients followed for 3 to 43 months (median 19 months) only 3 had relapse at 3, 5 and 18 months after orchiectomy with nonbulky retroperitoneal disease: 1 patient had disease 17 months after salvage infradiaphragmatic radiation therapy, 1 had an increase in beta-human chorionic gonadotropin 11 months after radiation therapy, presumably due to occult nonseminoma, and he is receiving chemotherapy, and 1 has not yet completed treatment. Further followup is necessary to determine ultimate survival, since a risk for later relapse exists. However, to date it does not appear as if the outcome has been compromised when surveillance was applied in place of routine adjuvant radiotherapy.
Monolithic two-dimensional surface emitting arrays of GaAs/AlGaAs lasers (1988)

Abstract Surface emitting lasers are of interest for various applications such as monolithic two-dimensional arrays and optical interconnects for integrated optics. Moreover, surface emitting lasers offer the advantage of wafer processing and testing. Several approaches for achieving surface emission are described. In addition, TRW s fabrication of a large monolithic two dimensional array of GaAs/AlGaAs surface emitting lasers which contains a total of 100 lasers is reported.
Radiation Oncology (1996)

Three important aspects of radiation oncology are potentially important advances in cancer treatment. The first is a multidisciplinary therapeutic approach with important clinical application, the second is progress in the physics of radiation therapy that has clinical ramifications and for which there are recently published clinical results, and the third is an exciting laboratory study that soon will be translated to clinical practice. In an attempt to develop a curative approach to locally advanced prostate cancer, a large cooperative group trial compared radiation therapy alone with radiation therapy and simultaneous androgen deprivation.<sup>1</sup>In this study, patients with lesions too large for surgery but without evidence of distant metastases were randomly allocated to receive radiation therapy or total androgen blockade using a luteinizing hormone—releasing hormone agonist and an antiandrogen combined with radiation therapy. The treatment technique involved giving the hormone blockade for 2 months and then starting the radiation therapy
Transmit Beamforming Based Inter-Cell Interference Alignment and User Selection with CoMP (2010)

Recently, two types of coordinated multiple point transmission (CoMP) technologies - joint processing and transmission (JPT) and coordinated scheduling and beamforming(CSB) - have been proposed to the latest cellular communication standard named as a Network MIMO, to improve the performance of cell-edge users who suffer strong ICI. In this paper, we investigate an ICI cancelation employing a user selection algorithm associated with CoMP-CSB, which is more practically used for cellular networks. Under the partial channel state information (CSI) and no data sharing condition, each base station (BS)concentrates more on the direction of the interference to users located at the adjacent cells during the user selection process.
Design of high-input voltage regulator modules with a novel integrated magnetics (2002)

A novel integrated magnetic structure was proposed to improve the performance of high-input voltage regulator modules (VRMs) by significantly reducing the leakage inductance of magnetics. Another benefits of using the proposed structure include reduced core loss, simplified manufacture process and reduction of the primary current ripple. As a result, the size and cost of VRMs could be reduced greatly. The concept was demonstrated on a push-pull forward VRM, which delivers power from a 48-V input to a 1.2-1.5 V/70 A microprocessor load.
Quasimetagenomics-Based and Real-Time-Sequencing-Aided Detection and Subtyping of Salmonella enterica from Food Samples (2017)

Metagenomics analysis of food samples promises isolation-independent detection and subtyping of foodborne bacterial pathogens in a single workflow. The selective concentration of <i>Salmonella</i> genomic DNA by immunomagnetic separation (IMS) and multiple displacement amplification (MDA) shortened the time for culture enrichment of <i>Salmonella</i>-spiked raw chicken breast samples by over 12 h while permitting serotyping and high-fidelity single nucleotide polymorphism (SNP) typing of the pathogen using short shotgun sequencing reads. The herein-termed quasimetagenomics approach was evaluated on <i>Salmonella</i>-spiked lettuce and black peppercorn samples as well as retail chicken parts naturally contaminated with different serotypes of <i>Salmonella</i> Culture enrichment of between 8 and 24 h was required for detecting and subtyping naturally occurring <i>Salmonella</i> from unspiked chicken parts compared with 4- to 12-h culture enrichment when <i>Salmonella</i>-spiked food samples were analyzed, indicating the likely need for longer culture enrichment to revive low levels of stressed or injured <i>Salmonella</i> cells in food. A further acceleration of the workflow was achieved by real-time nanopore sequencing. After 1.5 h of analysis on a potable sequencer, sufficient data were generated from sequencing the IMS-MDA products of a cultured-enriched lettuce sample to enable serotyping and robust phylogenetic placement of the inoculated isolate.<b>IMPORTANCE</b> Both culture enrichment and next-generation sequencing remain time-consuming processes for food testing, whereas rapid methods for pathogen detection are widely available. Our study demonstrated a substantial acceleration of these processes by the use of immunomagnetic separation (IMS) with multiple displacement amplification (MDA) and real-time nanopore sequencing. In one example, the combined use of the two methods delivered a less than 24-h turnaround time from the collection of a <i>Salmonella</i>-contaminated lettuce sample to the phylogenetic identification of the pathogen. An improved efficiency such as this is important for further expanding the use of whole-genome and metagenomics sequencing in the microbial analysis of food. Our results suggest the potential of the quasimetagenomics approach in areas where rapid detection and subtyping of foodborne pathogens are important, such as for foodborne outbreak response and the precision tracking and monitoring of foodborne pathogens in production environments and supply chains.
Using CrisisKit and MOPED to improve emergency management team training (2004)

In order to reduce the effects of a disaster, people in the emergency management organization have to be trained. In recent years training emergency management teams has become a bigger issue. A realistic and effective training of emergency management teams however is a difficult matter. We search for ways to improve this kind of training and to reduce the costs. In this paper two tools that can be used to improve emergency management training, CrisisKit and MOPED, will be discussed.
The Use of Computers in Flight Testing (1975)

Flight testing of modern high performance aircraft has generated an increasingly complex data handling workload and this contributes significantly to the duration and cost of flight test programmes. Automation of this critical data handling process can reduce the high cost of such a programme by reducing its duration. The effects of automation of data flow at the ground station can be enhanced by the use of immediate flight analysis of data telemetered from the aircraft.
Die Fokussierung von Wasserstoßwelten zur Lithotripsie durch verschiedene Ellipsoidreflektoren - Use of Various Ellipsoidal Reflectors for Focusing Water Shock Waves for Lithotripsy (1989)

Article Die Fokussierung von Wasserstoßwelten zur Lithotripsie durch verschiedene Ellipsoidreflektoren - Use of Various Ellipsoidal Reflectors for Focusing Water Shock Waves for Lithotripsy was published on January 1, 1989 in the journal Biomedical Engineering / Biomedizinische Technik (volume 34, issue 4).
The Caspase-Generated Fragments of PKR Cooperate to Activate Full Length PKR and Inhibit Translation (2004)

info:eu-repo/semantics/published