gebhart/patrepeval huggingface dataset:
Statistical Characterization and Computationally Efficient Modeling of a Class of Underwater Acoustic Communication Channels (2013)

Underwater acoustic channel models provide a tool for predicting the performance of communication systems before deployment, and are thus essential for system design. In this paper, we offer a statistical channel model which incorporates physical laws of acoustic propagation (frequency-dependent attenuation, bottom/surface reflections), as well as the effects of inevitable random local displacements. Specifically, we focus on random displacements on two scales: those that involve distances on the order of a few wavelengths, to which we refer as small-scale effects, and those that involve many wavelengths, to which we refer as large-scale effects. Small-scale effects include scattering and motion-induced Doppler shifting, and are responsible for fast variations of the instantaneous channel response, while large-scale effects describe the location uncertainty and changing environmental conditions, and affect the locally averaged received power. We model each propagation path by a large-scale gain and micromultipath components that cumulatively result in a complex Gaussian distortion. Time- and frequency-correlation properties of the path coefficients are assessed analytically, leading to a computationally efficient model for numerical channel simulation. Random motion of the surface and transmitter/receiver displacements introduce additional variation whose temporal correlation is described by Bessel-type functions. The total energy, or the gain contained in the channel, averaged over small scale, is modeled as log-normally distributed. The models are validated using real data obtained from four experiments. Specifically, experimental data are used to assess the distribution and the autocorrelation functions of the large-scale transmission loss and the short-term path gains. While the former indicates a log-normal distribution with an exponentially decaying autocorrelation, the latter indicates a conditional Ricean distribution with Bessel-type autocorrelation.
Electrical characteristics of TiN contacts to <i>N</i> silicon (1981)

We have performed a detailed investigation of TiN contacts on n-type silicon. The barrier height was found to be 0.49±0.01 V and the contact resistivity on 0.001-Ω cm substrates below 10−4 Ω cm2. The TiN layers were produced by reactive sputtering. The resistivity of the layers depends on the partial pressure of N2 in the N2+Ar sputtering gas mixture. A minimum of 55 μΩ cm was obtained, which is below the resistivity of pure Ti films. Finally, we have developed two etching solutions which allow patterning of TiN layers using conventional photolithography techniques.
Routing Protocols simulation for Efficiency Applications in Vehicular Environments (2013)

Los recientes esfuerzos de investigación realizados desde la comunidad académica, la industria automovilística y el sector de transportes, apuntan a los sistemas inteligentes de transporte como una tecnología clave para mejorar la seguridad en las carreteras, la eficiencia en el tráfico y el confort de los conductores. Las redes vehiculares Ad Hoc [VANETs] tienen el potencial de habilitar aplicaciones para seguridad en el tráfico, eficiencia en el transporte y movilidad sostenible. Los métodos de diseminación y los mecanismos de enrutamiento desempeñan un papel esencial en el diseño y la caracterización de las aplicaciones vehiculares. Este artículo provee un marco de referencias de las redes vehiculares ad hoc, describe sus conceptos fundamentales, los estándares de comunicación y las aplicaciones vehiculares. Presenta además los protocolos de enrutamiento para VANETs y los resultados de la simulación para el protocolo Geocast Distributed Robust Geocast.
Differentiation of benign monoclonal gammopathy and smouldering multiple myeloma from frank myeloma. (1982)

Circulating immunoglobulin (Ig) secreting cells of each type of the different Ig classes were enumerated using a reverse haemolytic plaque assay in nine subjects with the pre-clinical phase of IgG myeloma (six with benign monoclonal gammopathy and three with smouldering multiple myeloma). A shift in the ratio of IgG kappa to IgG lambda secreting cells without a significant increase in the total number of IgG secreting cells, that is the number of IgG kappa plus IgG lambda secreting cells, was a constant feature noted in every subject.
A Kind of Identity Authentication under Cloud Computing Environment (2014)

An identity authentication scheme is proposed combining with biometric encryption, public key cryptography of homomorphism and predicate encryption technology under the cloud computing environment. Identity authentication scheme is proposed based on the voice and homomorphism technology. The scheme is divided into four stages, register and training template stage, voice login and authentication stage, authorization stage, and audit stage. The results prove the scheme has certain advantages in four aspects.
Asymmetric and Symmetric Membrane Reconstitution by Detergent Elimination (1981)

The dissociation and reconstitution of the Semliki Forest virus membrane using the nonionic detergent octyl beta-D-glucoside was studied by sucrose density gradient centrifugation. The dissociation occurred in three stages: lysis at a free equilibrium octyl glucoside concentration of 14--18 mM, solubilization at 18--20 mM, and delipidation of the spike glycoproteins at the critical micellar concentration (22 mM) or higher. After solubilization the spike glycoproteins were present as soluble complexes with sedimentation coefficients of 19 S and 6 S. The 6-S form probably corresponded to a glycoprotein monomer complexed to detergent and the 19-S form consisted of oligomeric detergent-protein complexes. The two forms were in slow equilibrium with each other. When the soluble spike protein complexes and egg lecithin solubilized with octyl glucoside were mixed and the octyl glucoside concentration lowered either by dialysis or by dilution, reconstitution occurred. Three types of products were obtained: vesicles with 30% of the spike protein facing inwards and 70% facing outwards, vesicles with virtually all (95%) of the spike proteins pointing outwards, and small protein-rich soluble aggregates [Helenius et al. (1977) J. Cell Biol. 75, 866]. It was demonstrated that during reconstitution the symmetric vesicles were formed at 19 mM free equilibrium octyl glucoside by the association of the 6-S protein complexes with the phospholipids, and the asymmetric vesicles were formed at 10--16 mM octyl glucoside when the 19-S complexes associated with the lipids. Asymmetric membrane vesicles were also obtained when membrane penicillinase from Bacillus licheniformis was reconstituted with egg lecithin using octyl glucoside. It could be shown that the penicillinase was oligomeric at the octyl glycoside concentration where the reconstitution occurred. The results demonstrate that different mechanisms of reconstitution give rise to the symmetric and the asymmetric vesicles. The critical factor in determining the mechanism is the state of aggregation of the proteins at the octyl glucoside concentration where membranes begin to form from the solubilized lipids.
Induction Heating and Heat Treatment (2014)

Volume 4C is a comprehensive guide to electromagnetic induction and how to employ it in heat treating, metalworking, and materials manufacturing. Using diagrams, photos, and data plots, the volume reveals the science behind induction heating processes such as induction hardening, tempering, stress relieving, melting, brazing, soldering, and the preheating of metals and alloys prior to working. It also presents practical information on process control, modeling and simulation, and induction heating equipment, including high-voltage transformers, power supplies, and atmospheric chambers. In addition, the volume offers insight on quality assurance, maintenance, and energy use, and it reviews international standards on allowable levels of exposure to electromagnetic fields. For information on the print version of Volume 4C, ISBN: 978-1-62708-012-5, follow this link.
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells (1998)

Cdc6 has a critical regulatory role in the initiation of DNA replication in yeasts, but its function in mammalian cells has not been characterized. We show here that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells, both in culture and within tissues of intact animals. During the transition from a growth-arrested to a proliferative state, transcription of mammalian Cdc6 is regulated by E2F proteins, as revealed by a functional analysis of the human Cdc6 promoter and by the ability of exogenously expressed E2F proteins to stimulate the endogenous Cdc6 gene. Immunodepletion of Cdc6 by microinjection of anti-Cdc6 antibody blocks initiation of DNA replication in a human tumor cell line. We conclude that expression of human Cdc6 is regulated in response to mitogenic signals though transcriptional control mechanisms involving E2F proteins, and that Cdc6 is required for initiation of DNA replication in mammalian cells.
INHIBITION OF BEER-SPOILAGE LACTIC ACID BACTERIA BY NISIN (1985)

149 strains of bacteria, mostly brewery contaminants able to spoil wort or beer, and 12 brewing strains of yeast (8 ale and 4 lager strains) have been screened using a well-test assay for sensitivity to the food preservative, Nisin (E234), Nisin inhibited growth of 92% of the gram-positive strains, predominantly lactic acid bacteria of the genera Lactobacillus and Pediococcus. In contrast, all 32 gram-negative strains tested, except 3 Flavobacter strains, were Nisin-resistant; in addition none of the brewing yeasts showed Nisin-sensitivity. Therefore. Nisin has potential applications in preventing spoilage of worts or beers by lactic acid bacteria.
Automatic image clustering using a swarm intelligence approach (2011)

In order to implement clustering under the condition that the number of clusters is not known a priori, we propose in this paper ACPSO a novel automatic image clustering algorithm based on particle swarm optimization algorithm. ACPSO can partition image into compact and well separated clusters without any knowledge on the real number of clusters. ACPSO used a novel representation scheme for the search variables in order to determine the optimal number of clusters. The partition of each particle of the swarm evolves using evolving operators which aim to reduce dynamically the number of clusters centers. Experimental results on real images demonstrate the effectiveness of the proposed approach.
Neuronal DNA Methylation Profiling of Blast-Related Traumatic Brain Injury (2015)

Long-term molecular changes in the brain resulting from blast exposure may be mediated by epigenetic changes, such as deoxyribonucleic acid (DNA) methylation, that regulate gene expression. Aberrant regulation of gene expression is associated with behavioral abnormalities, where DNA methylation bridges environmental signals to sustained changes in gene expression. We assessed DNA methylation changes in the brains of rats exposed to three 74.5 kPa blast overpressure events, conditions that have been associated with long-term anxiogenic manifestations weeks or months following the initial exposures. Rat frontal cortex eight months post-exposure was used for cell sorting of whole brain tissue into neurons and glia. We interrogated DNA methylation profiles in these cells using Expanded Reduced Representation Bisulfite Sequencing. We obtained data for millions of cytosines, showing distinct methylation profiles for neurons and glia and an increase in global methylation in neuronal versus glial cells (p<10(-7)). We detected DNA methylation perturbations in blast overpressure-exposed animals, compared with sham blast controls, within 458 and 379 genes in neurons and glia, respectively. Differentially methylated neuronal genes showed enrichment in cell death and survival and nervous system development and function, including genes involved in transforming growth factor β and nitric oxide signaling. Functional validation via gene expression analysis of 30 differentially methylated neuronal and glial genes showed a 1.2 fold change in gene expression of the serotonin N-acetyltransferase gene (Aanat) in blast animals (p<0.05). These data provide the first genome-based evidence for changes in DNA methylation induced in response to multiple blast overpressure exposures. In particular, increased methylation and decreased gene expression were observed in the Aanat gene, which is involved in converting serotonin to the circadian hormone melatonin and is implicated in sleep disturbance and depression associated with traumatic brain injury.
Measurement of Humic and Fulvic Acid Concentrations and Dissolution Properties by a Rapid Batch Procedure (2007)

Although humic substances (HS) strongly facilitate the transport of metals and hydrophobic organic contaminants in environmental systems, their measurement is hampered by the time-consuming nature of currently available methods for their isolation and purification. We present and apply a new rapid batch method to measure humic (HA) and fulvic (FA) acid concentrations and dissolution properties in both solid and aqueous samples. The method is compared with the conventional procedures and is shown to substantially facilitate HS concentration measurements, particularly for applications such as geochemical modeling where HS purification is not required. The new method can be performed within 1.5-4 h per sample and multiple samples can be processed simultaneously, while the conventional procedures typically require approximately 40 h for a single sample. In addition, specific dissolution properties of HS are identified and are consistent with recent views on the molecular structure of HS that emphasize molecular interactions of smaller entities over distinct macromolecular components. Because the principles of the new method are essentially the same as those of generally accepted conventional procedures, the identified HA and FA properties are of general importance for the interpretation of the environmental occurrence and behavior of HS.
Reconfigurable group robots adaptively transforming a mechanical structure - Crawl motion and adaptive transformation with new algorithms (2006)

This paper describes group robots adaptively construct a mechanical structure. The feature of the robots is high rigidity by adopting sliding mechanisms. This study discusses algorithms of crawl motion and adaptive construction considering mechanical constraints of the robots. The proposed algorithm is based on local communication of the robots. We introduce a scheme of a temporary leader which is autonomously specified by form of the structure. The scheme decreases amount of information in communication between the robots. The experimental demonstrations are also shown in this paper.
Regulation of rDNA transcription in chloroplasts: promoter exclusion by constitutive repression. (1994)

Spinach chloroplasts contain two types of RNA polymerases. One is multimeric and Escherichia coli-like. The other one is not E. coli-like and might represent a monomeric enzyme of 110 kD. The quantitative relation of the two polymerases changes during plant development. This raises the question, how are plastid genes transcribed that contain E. coli-like and non-E. coli-like promoter elements during developmental phases when both enzymes are present? Transcription of the spinach plastid rrn operon promoter is initiated at three sites: P1, PC, and P2. P1 and P2 are preceded by E. coli-like promoter elements that are recognized by E. coli RNA polymerase in vitro. However, in vivo, transcription starts exclusively at PC. We analyzed different promoter constructions using in vitro transcription and gel mobility-shift studies to understand why P1 and P2 are not used in vivo. Our results suggest that the sequence-specific DNA-binding factor CDF2 functions as a repressor for transcription initiation of the E. coli-like enzyme at P1 and P2. We propose a mechanism of constitutive repression to keep the rrn operon in all developmental phases under the transcriptional control of the non-E. coli-like RNA polymerase.
Sentiment-Aspect Extraction based on Restricted Boltzmann Machines (2015)

Linlin Wang, Kang Liu, Zhu Cao, Jun Zhao, Gerard de Melo. Proceedings of the 53rd Annual Meeting of the Association for Computational Linguistics and the 7th International Joint Conference on Natural Language Processing (Volume 1: Long Papers). 2015.
Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model (2008)

Hyperphosphorylation of tau at multiple sites has been implicated in the formation of neurofibrillary tangles in Alzheimer's disease; however, the relationship between toxicity and phosphorylation of tau has not been clearly elucidated. Putative tau kinases that play a role in such phosphorylation events include the proline-directed kinases glycogen synthase kinase-3beta (GSK-3beta) and cyclin-dependent kinase 5 (Cdk5), as well as nonproline-directed kinases such as microtubule affinity-regulating kinase (MARK)/PAR-1; however, whether the cascade of events linking tau phosphorylation and neurodegeneration involves sequential action of kinases as opposed to parallel pathways is still a matter of controversy. Here, we employed a well-characterized Drosophila model of tauopathy to investigate the interdependence of tau kinases in regulating the phosphorylation and toxicity of tau in vivo. We found that tau mutants resistant to phosphorylation by MARK/PAR-1 were indeed less toxic than wild-type tau; however, this was not due to their resistance to phosphorylation by GSK-3beta/Shaggy. On the contrary, a tau mutant resistant to phosphorylation by GSK-3beta/Shaggy retained substantial toxicity and was found to have increased affinity for microtubules compared with wild-type tau. The fly homologs of Cdk5/p35 did not have major effects on tau toxicity or phosphorylation in this model. These data suggest that, in addition to tau phosphorylation, microtubule binding plays a crucial role in the regulation of tau toxicity when misexpressed. These data have important implications for the understanding and interpretation of animal models of tauopathy.
A Heuristic Model for Scheduling Large Projects with Limited Resources (1967)

Present PERT-type scheduling models implicitly assume unlimited availability of resources. As most project schedulers are aware, however, activities may be constrained in their start dates by availability of resources as well as by technological orderings. Analytic solutions to the limited-resource, project scheduling problem are infeasible at present for all but small projects; heuristic approaches seem most promising of useful results. One such approach, described here, is a computer model capable of scheduling single or multiple projects within resource limits and other constraints commonly encountered by the project scheduler. The basic formulation of the model is discussed along with its scheduling heuristics which determine the period-by-period allocation of resources to activities in a project. By changing certain parameters and heuristics in the model, one can simulate project scheduling under varying constraints and scheduling rules. Applications of the model to a number of fictitious and real projects are described.
Impregnation of plasmid DNA into three-dimensional PLGA scaffold enhances DNA expression of mesenchymal stem cells in vitro. (2012)

Current efforts had been made to undertake a three-dimensional (3-D) reverse transfection of bone marrow-derived mesenchymal stem cells (BM-MSCs) in PLGA scaffolds. As a kind of multipotent stem cells, BM-MSCs show great potential and tremendous capacity in the gene transfection field and PLGA 3-D scaffold has been shown to be a biomaterial that provides structural support to cells proliferation and tissue engineering. The objective of this study was to assess the transfection efficiency of BM-MSCs with a 3-D reverse transfection method by using PLGA scaffold and observe the SEM photographs of BM-MSCs cultured on PLGA scaffold. BM-MSCs were cultured in 3-D PLGA scaffold which was incorporated with pullulan-spermine/pGL3. It was shown that the gene expression duration of BM-MSCs transfected using 3D reverse method with pullulan-spermine/DNA in the presence of serum maintained 12 days at high levels as compared with the plasmid DNA in medium, and scanning electronic microscopy (SEM) photographs of BM-MSCs cultured on PLGA scaffold exhibited robust cell attachment and viability when cultured in PLGA scaffold in vitro. This study demonstrates that the 3-D reverse transfection method of BM-MSCs using PLGA scaffold could achieve long gene expression in a relatively high level, therefore this transfection system is promising in gene transfection and tissue engineering.
Ecological improvement of the vending machine using LCA method (2003)

"LCA (life cycle assessment)", which can assess the environmental aspect and potential impact associated with a product "from the cradle to the grave" synthetically, has become noteworthy. The software "MieLCA", which can be operated easily on a personal computer to conduct LCA-NETS (Numerical Eco-Load Total Standardization) was composed by employing the LCA method "ESS" (Eco-Load Standardization System). The assessment of various types of industrial products can be performed by applying "MieLCA". On the other hand, the vending machine has just as much to do with the environment as other industrial products. In addition to conducting such an assessment, the ecological improvement was performed by taking account of the concept of reuse etc. As a case study, the evaluation of environmental performance of a vending machine is discussed.
Mechanical Performance of Polyiosoprene Copolymer Anion Exchange Membranes by Varying Crosslinking Methods (2015)

Anion exchange membranes (AEM) are polymer electrolytes that facilitate ion transport in alkaline fuel cells and electrochemical devices. Fabrication of mechanically durable AEMs with high ionic conductivity is a challenge. Here, a copolymer of isoprene and vinylbenzyl trimethylammonium and a terpolymer of isoprene, vinylbenzyl trimethylammonium and styrene were crosslinked by various methods, and properties, including conductivity and mechanical strength, were investigated at dry and saturated conditions. Polymer chemistry and degree of crosslinking significantly influenced conductivity, swelling, and mechanical properties. The terpolymer had a higher proportion of vinylbenzyl trimethylammonium units increasing the ion exchange capacity (IEC), but membranes could still be rendered insoluble by crosslinking. The higher IEC of the terpolymer resulted in higher chloride conductivity, 20–75 mS/cm at 50°C and 95%RH, compared to 4–17 mS/cm for the copolymer at the same conditions. At dry conditions films were stiff, having Young's moduli between 100–740 MPa, but hydration caused severe softening, reducing moduli by 1–2 orders of magnitude. The severe softening effect of hydration was confirmed by dynamic mechanical analysis. The AEMs studied did not have adequate mechanical durability at hydrated conditions, additional work is needed to determine polymer chemistries and crosslinking methods that will produce robust AEMs for long-term use in fuel cells and electrochemical devices.