gebhart/patrepeval huggingface dataset:
Layer rotation: a surprisingly simple indicator of generalization in deep networks? (2019)

Our work presents empirical evidence that layer rotation, i.e. the evolution across training of thecosine distance between each layer’s weight vector and its initialization, constitutes an impressively consistent indicator of generalization performance. Compared to previously studied indicators of generalization, we show that layer rotation has the additional benefit of being easily monitored and controlled, as well as having a network independent optimum: the training procedures during which all layers’ weights reach a cosine distance of 1 from their initialization consistently outperform other configurations -by up to 20% test accuracy. Finally, our results also suggest that the study of layer rotation can provide a unified framework to explain the impact of weight decay and adaptive gradient methods on generalization.
What is the Reading Component Skill Profile of Adolescent Struggling Readers in Urban Schools? (2009)

The purpose of this descriptive study was to examine the component reading skills of adolescent struggling readers attending urban high schools. Specifically, 11 measures of reading skills were administered to 345 adolescent readers to gain a research-based perspective on the reading skill profile of this population. Participants were assessed in the domains of word level, fluency, vocabulary, and comprehension. Analysis of the results found that 61% of the struggling adolescent readers had significant deficits in all of the reading components listed above. Subgroups of struggling readers showed similar but more severe patterns. For example, students with learning disabilities scored significantly below the levels of the struggling reader group at large. In contrast, most proficient readers scored high on all measures of reading with above-average component reading skills in word level, vocabulary, and comprehension. The lowest skill area for the proficient reader group was fluency, where they scored at the average level. Implications for policy and instructional programming are discussed.
Automatic Estimation of Midsagittal Plane and AC-PC Alignment Based on Nonrigid Registration (2006)

Identifying the anterior and posterior commissures as well as the midsagittal plane in magnetic resonance brain images is a critical first step in the normalization process underlying group studies. We present a fully automatic algorithm that locates these structures with high accuracy. Estimates of all three landmarks are achieved first with a nonrigid registration algorithm and further optimization is used to refine these estimates. Extensive validation experiments involving both simulated and real data sets demonstrate the accuracy and robustness of the proposed method.
Multiparadigm visual programming language (2002)

Multiparadigm visual programming languages and their application to general-purpose programming are discussed. Multiparadigm languages are compared to single paradigm languages. A multiparadigm visual programming language called the Visual Toolset is described. An application example using the Visual Toolset is given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
[(C6H4S2)Ni(-‘S3')Fe(CO)(PMe3)2]: A Dinuclear [NiFe] Complex Modeling the [(RS)2Ni(-SR)2Fe(CO)(L)2] Core of [NiFe] Hydrogenase Centers (2002)

Attempts to model the active sites of [NiFe] hydrogenases have yielded numerous NiFe thiolate complexes but never a species with the characteristic [(RS)2Ni(μ-SR)2Fe(CO)(CN)2] core. The NiII/FeII title complex represents the PMe3 derivative. Its ν(CO) frequency of 1948 cm−1 corresponds to that of 1940 cm−1 for [NiFe] hydrogenase in the Ni–R state.
Integration of SiCN as a low κ etch stop and Cu passivation in a high performance Cu/low κ interconnect (2003)

This paper describes the integration of a silicon carbon nitride (SiCN) copper passivation and etch stop layer into a Cu low k dielectric interconnect technology. The incorporation of SiCN improves interconnect performance by virtue of its lower dielectric constant as compared to silicon nitride, and through changes to the process integration made possible by the improved etch selectivity and good copper interface properties.
Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning (2014)

The current study evaluated the stability potential of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning. The drug combinations were fabricated in an adhesive matrix system supported by a backing membrane and attached to a temporary release liner. Stability testing of the optimized formulation was established for 6 months under accelerated study conditions as per International Conference on Harmonisation guidelines. Results obtained after 6 months showed that the optimized patch formulation was stable with respect to drugs content, pH, diffusion, visual inspection, and other analytical parameters.
Ephemeral Data Handling in Microservices (2019)

Ephemeral data handling, whereby processed data do not persist, is an emerging requirement of connected IT systems, due to storage constraints (IoT) or regulatory demands (eHealth, GDPR). We present ongoing work on TQuery, a query language for ephemeral data handling in microservices.
Review on The Role of Zn2+ Ions in Viral Pathogenesis and the Effect of Zn2+ Ions for Host Cell-Virus Growth Inhibition (2019)

Zinc element is an essential micronutrient for human health. Zinc controls the enzymes that operate and renew the cells in our bodies, in which zinc play in the maintenance of immune functions including cellular and humoral immunity and changes.
The Soluble Wnt Receptor Frizzled8CRD-hFc Inhibits the Growth of Teratocarcinomas <i>In vivo</i> (2007)

Wnt signaling is important for normal cell proliferation and differentiation, and mutations in pathway components are associated with human cancers. Recent studies suggest that altered wnt ligand/receptor interactions might also contribute to human tumorigenesis. Therefore, agents that antagonize wnt signaling at the extracellular level would be attractive therapeutics for these cancers. We have generated a soluble wnt receptor comprising the Frizzled8 cysteine-rich domain (CRD) fused to the human Fc domain (F8CRDhFc) that exhibits favorable pharmacologic properties in vivo. Potent antitumor efficacy was shown using the mouse mammary tumor virus-Wnt1 tumor model under dosing conditions that did not produce detectable toxicity in regenerating tissue compartments. In vitro, F8CRDhFc inhibited autocrine wnt signaling in the teratoma cell lines PA-1, NTera-2, Tera-2, and NCCIT. In vivo, systemic administration of F8CRDhFc significantly retarded the growth of tumor xenografts derived from two of these cell lines, PA-1 and NTera-2. Pharmacodynamic markers of wnt signaling, identified by gene expression analysis of cultured teratoma cells, were also modulated in the tumor xenografts following treatment with F8CRDhFc. Additionally, these markers could be used as indicators of treatment efficacy and might also be useful in identifying patients that would benefit from the therapeutic agent. This is the first report showing the efficacy of a soluble wnt receptor as an antitumor agent and suggests that further development of wnt antagonists will have utility in treating human cancer.
Criteria for obtaining and interpreting breast thermograms (1976)

The thermal and graphic criteria which should be used to evaluate breast thermograms are outlined. Thermograms are then categorized as normal, suspicious, or abnormal on the basis of the criteria outlined. It is hoped that these criteria can be used widely to standardize breast thermographic evaluation.
ChemInform Abstract: KETONE‐DERIVED PEROXIDES. PART 1. SYNTHETIC METHODS (1980)

Abstract Verschiedene Darstellungswege von Peroxiden aus Ketonen werden beschrieben.
C‐wave resolution enhancement through birefringence compensation at the Valhall Field (2001)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2001C‐wave resolution enhancement through birefringence compensation at the Valhall FieldAuthors: Pierre‐Yves GrangerJean‐Michel BonnotAlain GresillaudAnne RolletPierre‐Yves GrangerCompagnie Générale de Géophysique, 91341 Massy, France, Jean‐Michel BonnotCompagnie Générale de Géophysique, 91341 Massy, France, Alain GresillaudCompagnie Générale de Géophysique, 91341 Massy, France, and Anne RolletCompagnie Générale de Géophysique, 91341 Massy, Francehttps://doi.org/10.1190/1.1816746 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1816746FiguresReferencesRelatedDetailsCited byAnisotropic correction of split shear wave and attribute analysis in Luojia blockRuyi Zhang, Yan-Guang Wang, Zhiqiang Sui, Qingfeng Kong, and Yu Zhen Liu1 September 20162D PP/PS-stereotomography: Application to a real 2D-OBC datasetGeophysical Prospecting, Vol. 56, No. 2 SEG Technical Program Expanded Abstracts 2001ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2001 Pages: 2135 publication data© 2001 Copyright © 2001 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 03 Jan 2005 CITATION INFORMATION Pierre‐Yves Granger, Jean‐Michel Bonnot, Alain Gresillaud, and Anne Rollet, (2001), "C‐wave resolution enhancement through birefringence compensation at the Valhall Field," SEG Technical Program Expanded Abstracts : 772-775. https://doi.org/10.1190/1.1816746 Plain-Language Summary PDF DownloadLoading ...
Optimizing synchronization operations for remote memory communication systems (2004)

Synchronization operations, such as fence and locking, are used in many parallel operations accessing shared memory. However, a process which is blocked waiting for a fence operation to complete, or for a lock to be acquired, cannot perform useful computation. It is therefore critical that these operations be implemented as efficiently as possible to reduce the time a process waits idle. These operations also impact the scalability of the overall system. As system sizes get larger, the number of processes potentially requesting a lock increases. In this paper we describe the design and implementation of an optimized operation which combines a global fence operation and a barrier synchronization operation. We also describe our implementation of an optimized lock algorithm. The optimizations have been incorporated into the ARMCI communication library. The global fence and barrier operation gives a factor of improvement of up to 9 over the current implementation in a 16 node system, while the optimized lock implementation gives up to 1.25 factor of improvement. These optimizations allow for more efficient and scalable applications.
Surgical repair of the prolapsing anterior leaflet in degenerative mitral valve disease. (2000)

AML prolapse repair is safe, durable, and therefore can be attempted even in mildly symptomatic patients. However, chordal shortening should be substituted by implantation of artificial chordae or by the flip-over technique.
Maximizing system capacity in a sub-symbol based DS-CDMA multiuser detector (2002)

A sub-symbol based multiuser detector for DS-CDMA systems was proposed in Uzmi and Mujtaba (1999). This paper addresses the optimization of such detectors to maximize the system capacity. It is shown that the maximum number of simultaneous users supported in a DS-CDMA system using a sub-symbol scheme can be increased by the proper selection of certain thresholds delineated in Uzmi and Mujtaba, and by imposing moderate synchronization requirements on the transmitters. It is also shown that, in a synchronized environment, performing with only one sub-symbol is enough for accommodating a fairly large number of users, if the system signal to noise ratio (SNR) is medium to high. It has been verified through simulations that the maximum number of simultaneous users depends on the degree of synchronism and is approximately given by the number of chips in the longest sub-symbol.
Role of early genes in pathogenesis of adenovirus pneumonia. (1990)

Intranasal inoculation of type 5 adenovirus into the cotton rat Sigmodon hispidus produces a pneumonia pathologically similar to that in humans, and it, therefore, provides an excellent animal model to investigate the pathogenesis of this disease. The goal of this study was to test the hypothesis that accumulation of viral structural proteins is responsible for a major portion of the cell-damage-producing disease. Since viral DNA replication is essential for synthesis of the viral structural proteins, which are products of late genes, the hypothesis was tested using mutants defective in genes required for DNA synthesis. Most experiments were done with the conditionally lethal temperature-sensitive (ts) mutant H5ts125, which contains a mutation in the early region 2A (E2A) gene encoding the DNA-binding protein. The data show that infection with 1 x 10(9.0) plaque-forming units of H5ts125 induced a pneumonia that was as extensive and qualitatively the same as that after wild-type adenovirus type 5 infection, although H5ts125 did not replicate to produce infectious virus. When cotton rats were infected with 1 x 10(8.0) plaque-forming units of wild-type adenovirus type 5 or H5ts125, the pneumonias that followed were pathologically similar; in the latter phases, however, wild-type virus produced slightly more extensive pneumonia than did H5ts125, probably because its replication permitted infection of more susceptible cells.
Immunization against Anaplasma phagocytophilum Adhesin Binding Domains Confers Protection against Infection in the Mouse Model (2020)

<i>Anaplasma phagocytophilum</i> causes granulocytic anaplasmosis, a debilitating infection that can be fatal in the immunocompromised. It also afflicts animals, including dogs, horses, and sheep. No granulocytic anaplasmosis vaccine exists. Because <i>A. phagocytophilum</i> is an obligate intracellular bacterium, inhibiting microbe-host cell interactions that facilitate invasion can disrupt infection. The binding domains of <i>A. phagocytophilum</i> adhesins <i>A. phagocytophilum</i> invasion protein A (AipA), <i>A. phagocytophilum</i> surface protein (Asp14), and outer membrane protein A (OmpA) are essential for optimal bacterial entry into host cells, but their relevance to infection <i>in vivo</i> is undefined. In this study, C57BL/6 mice were immunized with a cocktail of keyhole limpet hemocyanin-conjugated peptides corresponding to the AipA, Asp14, and OmpA binding domains in alum followed by challenge with <i>A. phagocytophilum</i> The bacterial peripheral blood burden was pronouncedly reduced in immunized mice compared to controls. Examination of pre- and postchallenge sera from these mice revealed that immunization elicited antibodies against AipA and Asp14 peptides but not OmpA peptide. Nonetheless, pooled sera from pre- and postchallenge groups, but not from control groups, inhibited <i>A. phagocytophilum</i> infection of HL-60 cells. Adhesin domain immunization also elicited interferon gamma (IFN-γ)-producing CD8-positive (CD8<sup>+</sup>) T cells. A follow-up study confirmed that immunization against only the AipA or Asp14 binding domain was sufficient to reduce the bacterial peripheral blood load in mice following challenge and elicit antibodies that inhibit <i>A. phagocytophilum</i> cellular infection <i>in vitro</i> These data demonstrate that AipA and Asp14 are critical for <i>A. phagocytophilum</i> to productively infect mice, and immunization against their binding domains elicits a protective immune response.
Optimizing SDRAM bandwidth for custom FPGA loop accelerators (2012)

Memory bandwidth is critical to achieving high performance in many FPGA applications. The bandwidth of SDRAM memories is, however, highly dependent upon the order in which addresses are presented on the SDRAM interface. We present an automated tool for constructing an application specific on-chip memory address sequencer which presents requests to the external memory with an ordering that optimizes off-chip memory bandwidth for fixed on-chip memory resource. Within a class of algorithms described by affine loop nests, this approach can be shown to reduce both the number of requests made to external memory and the overhead associated with those requests. Data presented shows a trade off between the use of on-chip resources and achievable off-chip memory bandwidth where a range of improvements from 3.6x to 4x gain in efficiency on the external memory interface can be gained at a cost of up to a 1.4x increase in the ALUTs dedicated to address generation circuits in an Altera Stratix III device.
Atelectasis during anaesthesia and in the postoperative period (1986)

Transverse sections of lung tissue were studied in patients by computerized tomography during anaesthesia and in the postoperative period. Eight patients were studied during intravenous (thiopentone) and six during inhalational (halothane) anaesthesia. The latter patients were studied during both spontaneous and mechanical ventilation. Five of the patients who underwent surgery for inguinal hernia and five patients in whom laparotomy was performed were studied 1 h and 24 h postoperatively. No patient showed any lung changes while awake preoperatively, and all patients developed dependent, crest-shaped lung densities within 5-10 min of anaesthesia. The densities comprised 3.4% of the lung volume in the caudal (basal) 5 cm of the lung tissue. No significant differences in the size and distribution of the densities were noted between spontaneous breathing and mechanical ventilation during anaesthesia, or between intravenous and inhalational anaesthesia. The densities remained in nine of ten patients 1 h postoperatively, and they remained in five of ten patients 24 h after anaesthesia. The densities are considered to be compression atelectases which may develop as a result of relaxation of the diaphragm. They may be important contributors to postoperative pulmonary complications.
Genetic analysis of a new mutation conferring cysteine auxotrophy in Saccharomyces cerevisiae: updating of the sulfur metabolism pathway. (1992)

We have identified a mutation in a gene of Saccharomyces cerevisiae, STR1, that leads to a strict nutritional requirement for cysteine. The str1-1 mutation decreases to an undetectable level the cystathionine gamma-lyase activity. This enzyme catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine. The phenotype induced by this mutation implies that, in S. cerevisiae, the sulfur atom of sulfide resulting from the reductive assimilation of sulfate is incorporated into a four carbon backbone yielding homocysteine, which, in turn, is the precursor of the biosynthesis of both cysteine and methionine. This also reveals that the direct synthesis of cysteine by incorporation of the sulfur atom into a three carbon backbone as found in Escherichia coli does not occur in S. cerevisiae. The study of the meiotic progeny of diploid strains heterozygous at the STR1 locus has shown that the str1-1 mutation undergoes a particularly high frequency of meiotic gene conversion.
Video-rate near-infrared optical tomography using spectrally encoded parallel light delivery (2005)

A novel parallel source implementation approach to near-infrared tomography is demonstrated through spectral encoding of the light delivery. This new technique allows many sources to be input into the tissue at the same time, and a high-resolution spectrometer is used to spatially spread out the signals from each spectrally encoded source. The parallel sampling of all sources at all detection locations renders rapid imaging. Acquisition of complete tomographic data sets at a video rate of 35 frames/s is achieved for imaging of a 6.35 mm diameter inclusion with an absorption coefficient of 0.01 mm(-1) and a reduced scattering coefficient of 1.5 mm(-1) that is moving along a circular path inside a 1% Intralipid solution.
Coulomb explosion in ultrashort pulsed laser ablation of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Al</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (2000)

Coulomb explosion (CE) is identified as the mechanism of ion ejection under low fluence ultrashort pulse laser ablation of crystalline ${\mathrm{Al}}_{2}{\mathrm{O}}_{3}.$ The ion momenta are equal during ``gentle'' ablation. This is explained by impulsive CE from the surface region lasting \ensuremath{\sim}1 ps. The onset of ``strong'' ablation leads to a decrease in the measured ion velocities. The kinetic energies rather than the momenta of the ions become equal. This regime is associated with strong plasma light emission and crater formation.
Principles of Radiographic Imaging (1991)

Principles of Radiographic Imaging , Principles of Radiographic Imaging , کتابخانه الکترونیک و دیجیتال - آذرسا
Antigen-Specific T Cell-Mediated Suppression: III. Induction of Antigen-Specific Suppressor T Cells (TS2) in L-Glutamic Acid60-L-Alanine30-L-Tyrosine10 (GAT) Responder Mice by Nonresponder-Derived GAT-Suppressor Factor (GAT-TSF) (1978)

Previous studies demonstrated that nonresponder (DBA/1)-derived suppressor factor specific for the random copolymer L-glutamic acid 60 -L-alanine 30 -L-tyrosine 10 (GAT-T s F) failed to suppress responder strain mice when administred at the same time as antigen (GAT) challenge. The present study demonstrates that if responder (BALB/c or A/J) spleen cells are preincubated with nonresponder GAT-T s F for 2 days in vitro , suppressor T cells (T s 2 ) are induced that can suppress syngeneic GAT plaque-forming cell responses in vivo or in vitro . This finding is in accord with T s 2 induction in nonresponder mice with the same GAT-T s F. Further, administration of nonresponder GAT-T s F to responder mice 7 days before in vivo antigen challenge suppressed subsequent GAT-PFC responses in these mice. Finally, the T s 2 induced in the same strain of mice (BALB/c) by GAT-T s F and by L-glutamic acid 50 -L-tyrosine 50 (GT)-specific T s F were shown to be able to suppress only the response to the inducing antigen, demonstrating the fine specificity of these T s 2 . The implications of this demonstration of nonresponder T s F activity in responder mice for an antigen under strict Ir gene control are discussed.