gebhart/patrepeval huggingface dataset:
Comparative Analysis of Transverse Intrafascicular Multichannel Electrode (TIME), Longitudinal Intrafascicular Electrode (LIFE) and Multipolar Cuff Electrode for the Selective Stimulation of Nerve Fascicles (2011)

International audience
Creating View-dependent Texture Maps (2002)

We present a technique for blending multiple images of an object into a single, view-dependent texture map for that object. This technique can be used for image-based rendering, when the object is known, or for “painting” a view-dependent texture map of an object. The technique provides a structured mechanism for combing images at different resolutions, producing a mip-map like structure with the different levels constructed from different images. The user controls the camera angles for which a given image is valid. The technique is also suitable for use on an object that will be animated.
Fluorescent Single-Molecular Core−Shell Nanospheres of Hyperbranched Conjugated Polyelectrolyte for Live-Cell Imaging (2009)

A water-soluble fluorescent hyperbranched conjugated polyelectrolyte (HCPE) with a unique double-layered architecture is synthesized via the combination of alkyne polycyclotrimerization and alkyne-azide “click” reaction for live-cell imaging. Because of the rigid conjugated core that offers shape persistence, and the water-soluble nonionic poly(ethylene glycol) shells that passivate the macromolecular surface, HCPE intrinsically forms single-molecular core−shell nanospheres with an average diameter of ∼10.7 nm and a narrow size distribution of ∼1.5, according to transmission electron microscopy images. The resulted organic nanospheres possess high quantum yield (30% in buffer), good solution stability, and low cytotoxicity. Using breast cancer cell MCF-7 as an example, these core−shell nanospheres are internalized efficiently by the cells and accumulated in the cytoplasm to give bright fluorescence. Photostability study reveals that these nanospheres are significantly more stable than commercial dyes, such as fluorescein, rhodamine, and Cy5, which demonstrates the great potential of organic polymeric nanomaterials in long-term clinical applications. In addition, the state-of-the-art synthetic methods used herein provide the feasibility and flexibility to modify both core and shell components of HCPE for specific biological applications.
Comparison of eosin and fluorescein conjugates for the photoinitiation of cell-compatible polymer coatings (2018)

Targeted photopolymerization is the basis for multiple diagnostic and cell encapsulation technologies. While eosin is used in conjunction with tertiary amines as a water-soluble photoinitiation system, eosin is not widely sold as a conjugate with antibodies and other targeting biomolecules. Here we evaluate the utility of fluorescein-labeled bioconjugates to photopolymerize targeted coatings on live cells. We show that although fluorescein conjugates absorb approximately 50% less light energy than eosin in matched photopolymerization experiments using a 530 nm LED lamp, appreciable polymer thicknesses can still be formed in cell compatible environments with fluorescein photosensitization. At low photoinitiator density, eosin allows more sensitive initiation of gelation. However at higher functionalization densities, the thickness of fluorescein polymer films begins to rival that of eosin. Commercial fluorescein-conjugated antibodies are also capable of generating conformal, protective coatings on mammalian cells with similar viability and encapsulation efficiency as eosin systems.
Synthesis of peptides analogous to the N-terminal eicosapeptide sequence of ribonuclease A. Part I. Synthesis of the orn<sup>10</sup>-hexapeptide analogue of the sequence 7–12 (1967)

Synthesis is described of the protected hexapeptide Nα-benzyloxycarbonyl-NÎµ-t-butoxycarbonyl-L-lysyl-L-phenylalanyl-γ-t-butyl-L-glutamyl-Nδ-t-butoxycarbonyl-L-ornithyl-L-glutaminyl-L-histidine methyl ester, analogous to positions 7–12 in the amino-acid sequence of bovine pancreatic ribonuclease A.The synthesis was carried out by coupling, by the azide procedure, the dipeptide Nα-benzyloxycarbonyl-NÎµ-t-butoxycarbonyl-L-lysyl-L-phenylalanine hydrazide with γ-t-butyl-L-glutamyl-Nδ-t-butoxycarbonyl-L-ornithyl-L-glutaminyl-L-histidine methyl ester.
Asymmetric hetero Diels-Alder reaction of .alpha.-alkoxy aldehydes with activated dienes. The scope of Lewis acid chelation-controlled cycloadditions (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAsymmetric hetero Diels-Alder reaction of .alpha.-alkoxy aldehydes with activated dienes. The scope of Lewis acid chelation-controlled cycloadditionsM. Mark Midland and Roger W. KoopsCite this: J. Org. Chem. 1990, 55, 17, 5058–5065Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/jo00304a018https://doi.org/10.1021/jo00304a018research-articleACS PublicationsRequest reuse permissionsArticle Views1386Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Single-pixel imaging 12 years on: a review (2020)

Modern cameras typically use an array of millions of detector pixels to capture images. By contrast, single-pixel cameras use a sequence of mask patterns to filter the scene along with the corresponding measurements of the transmitted intensity which is recorded using a single-pixel detector. This review considers the development of single-pixel cameras from the seminal work of Duarte et al. up to the present state of the art. We cover the variety of hardware configurations, design of mask patterns and the associated reconstruction algorithms, many of which relate to the field of compressed sensing and, more recently, machine learning. Overall, single-pixel cameras lend themselves to imaging at non-visible wavelengths and with precise timing or depth resolution. We discuss the suitability of single-pixel cameras for different application areas, including infrared imaging and 3D situation awareness for autonomous vehicles.
Research on Waterwall Dynamic Characteristics of a 600MW Supercritical Circulating Fluidized Bed Boiler (2009)

A mathematical model for the dynamic characteristics of the waterwall of the supercritical circulating fluidized bed(CFB) boiler was established on the basis of lumped parameter method.The second-time modeling was carried out,and the dynamic equation group which can be solved directly by numerical integration was derived.The simulation program for the dynamic characteristics was developed,which can calculate the dynamic characteristics of the waterwall response to step changes in fuel flow rate,the opening of the inlet valve of the steam turbine,flow rate and temperature of feed water at different load conditions,offering reference for boiler design and safe operation.The response characteristics of hot water section length,pressure,outlet enthalpy,working medium temperature and metal wall temperature of the waterwall of a self-developed 600 MW supercritical CFB boiler were derived when the flow rate,pressure,inlet enthalpy,heating load was changed at 30% of BMCR and 100% of BMCR load.Results show that the response parameters tends to be stable in some time after the disturbance occurs,which indicates that the flow system is stable,and the design and operation of the waterwall are safe and reliable.
Microdistribution and Feeding of the Net-Spinning Caddisflies (Trichoptera) of a Canadian Stream (1973)

Larvae of three species of net-spinning Trichoptera in a Canadian stream were found to prefer shallow, fast-flowing sites with large, moss-covered rocks. Several seasonal and interspecific differences were revealed. A philopotamid species was found to occupy a different niche from two hydropsychid species, chiefly in terms of food and feeding, but no major ecological differences could be demonstrated between the last-mentioned species-pair.
Ganglionic nAChRs and high‐affinity nicotinic binding sites are not equivalent (1986)

High-affinity (Kd approximately equal to 10 nM) binding sites for nicotine and acetylcholine (ACh) have recently been identified in vertebrate brain. It has been suggested that these sites are desensitized ganglionic (C6) nicotinic acetylcholine receptors (nAChRs). We have tested the pheochromocytoma cell line PC12, which is known to contain well-expressed C6 nAChRs, to determine if these nAChRs are associated with high-affinity [3H]ACh-binding sites. We found that the high-affinity nicotinic [3H]ACh-binding site is absent in PC12 cells. We also found that the concentration of nicotine or ACh necessary to desensitize carbamylcholine-stimulated Na+ flux was at least two orders of magnitude greater than the concentrations used in binding experiments. We conclude that high-affinity nicotinic binding sites are not equivalent to C6 ganglionic receptors.
A method for the fractionation and determination of carnitines in milk and milk products. (1988)

牛乳, 乳製品を対象に, Cの分画, アルカリ加水分解の条件ならびに放射能測定用の反応液組成など, Cの分画定量条件を検討した。1) 分画に用いる過塩素酸溶液は, 2～6%濃度のいずれによっても, 酸可溶性-C, 酸不溶性-Cの測定値に差を生じなかったが, 清澄な遠心上清がえられる6%濃度 (最終濃度3%) を採用した。2) 6%過塩素酸溶液 (最終濃度3%) で分画した酸可溶性画分には, 主として炭素数10以下の短鎖結合型-Cが, 酸不溶性画分には主として長鎖結合型-Cが分画されたが, 炭素数8～12の脂肪酸の結合型は, 少量ながら両画分に移行し, その境界は炭素数で明瞭に区分されるものではなかった。3) 過塩素酸分画でえられた結合型-Cの加水分解は, 比較的高濃度のアルカリ処理によるのが適当であった。また3.5N KOH中でも, 遊離-Cの損失はみられなかった。4) 牛乳のCは分画操作, アルカリ処理操作によって希釈され, 放射能測定用の検液50μ1中には1nmol以下となった。微量のCを測定するために, 反応液に含まれるacetyl-CoAの放射能を0.05μCi/5nmolにする必要があった。5) 反応液にトリス緩衝液を用いると, Cacetyl-transferaseの添加後の時間経過に伴って, 放射能測定値が高くなり, 測定精度が低下するが, リン酸緩衝液ではこの現象を認めなかった。6) 以上の結果から, Cの分画定量法を設定したが, 測定限界は放射能測定用の検液50μl中のC量として0. 05nmolで, 回収試験, 繰返し精度でも, ほぼ満足すべき結果がえられた。
Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research (2012)

Provide an accurate summary of the background, research objectives (including details of the species or strain of animal used), key methods, principal findings, and conclusions of the study.
Anaerobically digested bovine biofiber as a source of fiber for particleboard manufacturing: An economic analysis (2008)

This paper explores the physical and economic potential to substitute anaerobically digested bovine biofiber (ADBF) for wood in the making of particleboard. Laboratory tests indicated that replacement of one-half the wood in particleboard with ADBF produced panels that compared favorably to the requirements for commercial particleboard performance (specified by ANSI Standard A208.1–1999). The economic question hinges on the opportunity costs of alternative uses for ADBF. The current use is primarily animal bedding, and prices appear to be greater than those paid by particleboard plants for sawdust and planer shavings but less than for chips. ADBF is most similar in size to, thus most likely to be substitutable for, sawdust and shavings. At current bedding values, use for particleboard appears a less favorable alternative. However, this could be overcome by large-volume, long-term contractual arrangements that provide a secure long-term outlet for excess ADBF fiber that may otherwise not have value. For a particleboard operation, the opportunity for fiber diversification and the incorporation of post-industrial waste in the process offer strategic advantages.
Modification of Liposomes with Proteins by Dansyl-labeled Heterobifunctional Crosslinker (2010)

The introduction of a fluorescent chromaphore into bifunctional crosslinkers results in a molecule with normal crosslinker properties and a fluorescent group for straightforward quantification. This work describes the synthesis of the dansyl-labeled heterobifunctional crosslinker N-succinimidyl ε-N-dansyl α-N-(acetylthio)acetyllysine (dansyl-ATA-lysine-NHS) containing reactive N-hydroxysuccinimidyl (NHS) ester and sulfhydryl groups. The application of this crosslinker to conjugation of bovine serum albumin (BSA) protein to the surface of a liposome containing maleimide functions is also demonstrated. BSA was modified with the dansyl-labeled crosslinker and subsequently conjugated to liposomes containing reactive phospholipid derivative N-[4-(p-maleimidophenyl)butyryl]phosphatidylethanolamine and the degree of modification and conjugation were quantitatively determined by measuring the fluorescence emission of the dansyl group. The reliability of the fluorescence quantification was confirmed by a micro bio-barcode assay protein assay.
Powder and compaction characteristics of pregelatinized starches. (2012)

Pregelatinized starch is widely used as a pharmaceutical aid, especially as a filler-binder. It is known that the tableting performance of excipients could be affected by their source. The aim of this study was to evaluate the powder and tableting properties of pregelatinized starches obtained from yucca, corn and rice and compare those properties with those of Starch 1500. This material had the lowest particle size, and porosity and largest density and best flow. However, yucca starch and corn starch showed an irregular granule morphology, better compactibility and compressibility than Starch 1500. Their onset of plastic deformation and their strain rate sensitivity was comparable to that of Starch 1500. These two materials showed compact disintegration slower that Starch 1500. Conversely, rice starch showed a high elasticity, and friability, low compactibility, which are undesirable for direct compression. This study demonstrated the potential use of pregelatinized starches, especially those obtained from yucca and corn as direct compression filler-binders.
The Effectiveness of Right Heart Catheterization in the Initial Care of Critically Ill Patients (1997)

Comment: I cannot say more about this study (or say anything better) than what Ken Tuman and I wrote in a recent editorial.1 I believe this study adds nothing to the database we already had, and it accentuates the problem that we have with right heart catheterization which is: knowing when and where it is appropriate to perform right heart catheterization and treat the patient based on derived values. Clearly, we need a prospective, randomized, controlled study that is free of all the biases of observational studies (like this one) and cross-overs that the usual studies have (like many in the literature).
Camera localization by CAD model matching (2011)

This paper presents a system framework to realize camera localization relative to a 3D object. We adopt a Coarse-to-Fine strategy to locate the camera. First a series of rendered Computer Graphics (CG) images are compared with a real camera image. With an iterative linear search for the maximum Mutual Information (MI) among these comparisons, an initial camera pose estimation is obtained. Subsequently, for various kinds of objects, an update step of the pose estimation is realized by an edge-based object tracking method or a further search for the maximum MI with a smaller step size. To eliminate the pose estimation error due to the system coordinates transform error and camera calibration, a visual servo approach is adopted in the final step to adjust the camera to its final pose. The implementation of this framework is introduced in detail. The experiments results show that this framework is effective to locate the camera to its desired pose relative to 3D objects.
Combining Magnets and Dielectrics: Crystal Chemistry in the BaO—Fe<sub>2</sub>O<sub>3</sub>—TiO<sub>2</sub> System (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Reaction kinetics and gel effect on the polymerization of 2‐ethoxyethyl methacrylate and 2(2‐ethoxyethoxy) ethyl methacrylate (2002)

Abstract Polymerization kinetics at several temperatures of 2‐ethoxyethyl methacrylate (EEMA) and 2(2‐ethoxyethoxy) ethyl methacrylate (DEMA) in bulk and in dioxane solutions are described. The gel effect was never detected at monomer concentrations equal to or lower than 1 mol L −1 , although in the bulk polymerization both monomers display the gel effect at very low conversions. Because of the influence of the efficiency factor f on the polymerization rate, a theoretical kinetic interpretation of the changes in f with monomer and initiator concentrations and kinetic parameters was performed to achieve a better understanding of the mechanisms involved in radical polymerization. © 2002 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 40: 3987–4001, 2002
Three dimensional model of flow over a shallow trench (2004)

This paper describes the 3-D numerical modelling of flow over a shallow trench. The numerical scheme uses a finite difference scheme based on the Reynolds averaged Navier-Stokes equations using four turbulence closure models. It is important that the three dimensional circulation should be correctly represented by numerical schemes especially when these are used to solve problems involving such things as sediment transport or pollution dispersion. This paper examines the various trade-offs between simplifying assumptions and differing turbulence closure options used in the numerical model.
Evolution of protein phosphatases in plants and animals (2008)

Protein phosphorylation appears to be a universal mechanism of protein regulation. Genomics has provided the means to compile inventories of protein phosphatases across a wide selection of organisms and this has supplied insights into the evolution of this group of enzymes. Protein phosphatases evolved independently several times yielding the groups we observe today. Starting from a core catalytic domain, phosphatases evolved by a series of gene duplication events and by adopting the use of regulatory subunits and/or fusion with novel functional modules or domains. Recent analyses also suggest that the serine/threonine specific enzymes are more ancient than the PTPs (protein tyrosine phosphatases). It is likely that the latter played a key role at the onset of metazoan evolution in conjunction with the tremendous expansion of tyrosine kinases and PTPs at this point. In the present review, we discuss the evolution of the PTPs, the serine/threonine specific PPP (phosphoprotein phosphatase) and PPM (metallo-dependent protein phosphatase) families and the more recently discovered phosphatases that utilize an aspartate-based catalytic mechanism. We will also highlight examples of convergent evolution and several phosphatases which are unique to plants.
Orientation and ion-implanted transverse effects in self-aligned GaAs MESFET's (1987)

The orientation dependence of the threshold voltage and device transconductance of ion-implanted GaAs FET's has been investigated and modeled. The threshold voltages of the devices along the [011] and [01 <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">\bar{1}</tex> ] directions are different when the gate length is short (≤ 3 µm). Experimental results and theoretical calculations show that this is primarily due to the strain in the active channel, induced by the dielectric overlayer. For the short self-aligned gate structure, the lateral spread of the ion-implanted n <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> layer is important as well. When these two effects are taken into account, calculated results agree well with the experimental data for standard self-aligned gate structures, and self-aligned structures with a sidewall or T-gate, fabricated using lamp- or furnace-annealing processes. This model also allows us to simulate the threshold voltage and transconductance dependence on the annealing time for different device parameters (such as gate length and channel doping)and process variables (i.e., sidewall or T-gate dimensions and impurity diffusion constant). We also calculated the gate length dependence of the transconductance for devices fabricated using a sidewall process. Results of this calculation are compared with the experimental data for different sidewall thicknesses.
On improving local website search using web server traffic logs (2005)

In this paper we give a preliminary report on our study of the use of web server traffic logs to improve local search. Web server traffic logs are, typically, private to individual websites and as such -- are unavailable to traditional web search engines conducting searches across multiple web sites. However, they can be used to augment search performed by a local search engine, restricted to a single site.Web server traffic logs, which we will refer to as simply logs throughout this paper, contain information on traffic patterns on a web site. By using this information, instead of pure link counts in the computation of PageRank, we can obtain a new local measure of web site importance, based on frequency of visits to a page, rather than simply on the amount of links.In this paper we describe the architecture of a search engine we have built for the Eastern Kentucky University (EKU) website and some preliminary experiments we have conducted with it.
A survey on the channel assignment problem in wireless networks (2010)

Abstract Efficient allocation of channels for wireless communication in different network scenarios has become an extremely important topic of recent research. The main challenge lies in the fact that the channel allocation problem is NP‐complete. Because of a maximum allowable time limit imposed in practical situations for allocation of channels, sometimes we may need to be satisfied with a near‐optimal solution. In this correspondence, we present a discussion on the various challenges and approaches that have been used by different researchers to solve the problem of channel allocation taking into account different interference issues and efficient utilization of available communication channels for cellular mobile (including multimedia communication) environment and cognitive radio based networks. Copyright © 2010 John Wiley & Sons, Ltd.