gebhart/patrepeval huggingface dataset:
[An experimental study on the auditory brainstem response to electrical stimulation of the cochlea]. (1990)

This animal research was undertaken to study some important issues for cochlear implantation. This included investigations of 1) the difference in the auditory brainstem responses (ABRs) to extra- and intracochlear electrical stimulations. 2) stimulus parameters and ABRs to a bipolar intracochlear stimulation, and 3) electrode placements and ABRs. There were no distinct differences in waveforms and input-output curves of ABRs between extracochlear electrical stimulation and intracochlear bipolar stimulation of the cochlea. Changes in amplitude and latency of ABRs were investigated at changes of the pulse amplitude or the pulse width of stimulating electric rectangular waves. Increase in the pulse amplitude or the pulse width resulted in increase of the amplitude of ABRs and no increase in the ABR latency. This results showed the amplitude of ABR was dependent on the amount of electricity; coulomb. Electrically evoked ABRs were studied for stimulations at different sites of the cochlea. The ABR elicited with a bipolar electrode placed at the third turn of the cochlea had a longer latency of each peak of ABR waves than the one at the basal turn. This indicates that electrical stimulation with a bipolar electrode can give rise to a localized excitation in the cochlea and a latency change along the longitudinal axis of the cochlea, so that it suggests a multichannel cochlea implant system can transmit more information as a spacious pattern than a single channel system.
Antibodies against Glucan, Chitin, and <i>Saccharomyces cerevisiae</i> Mannan as New Biomarkers of <i>Candida albicans</i> Infection That Complement Tests Based on <i>C. albicans</i> Mannan (2008)

Antibodies against Saccharomyces cerevisiae mannan (ASCA) and antibodies against synthetic disaccharide fragments of glucans (ALCA) and chitin (ACCA) are biomarkers of Crohn's disease (CD). We previously showed that Candida albicans infection generates ASCA. Here, we explored ALCA and ACCA as possible biomarkers of invasive C. albicans infection (ICI). ASCA, ALCA, ACCA, and Candida mannan antigen and antibody detection tests were performed on 69 sera obtained sequentially from 18 patients with ICIs proven by blood culture, 59 sera from CD patients, 47 sera from hospitalized subjects colonized by Candida species (CZ), and 131 sera from healthy controls (HC). ASCA, ALCA, and ACCA levels in CD and ICI patients were significantly different from those in CZ and HC subjects (P<0.0001). In ICI patients, these levels increased as infection developed. Using ASCA, ALCA, ACCA, and Platelia Candida tests, 100% of ICIs were detected, with the kinetics of the antibody response depending on the patient during the time course of infection. A large number of sera presented with more than three positive tests. This is the first evidence that the detection of antibodies against chitin and glucans has diagnostic value in fungal infections and that these tests can complement more specific tests. Future trials are necessary to assess the value of these tests in multiparametric analysis, as well as their pathophysiological relevance.
Expression of Pax8 as a Useful Marker in Distinguishing Ovarian Carcinomas From Mammary Carcinomas (2008)

The ovary is a common site of involvement for metastasis and the breast is one of the most common sources. Metastatic breast carcinoma can mimic a primary ovarian carcinoma. Pax8 is a crucial transcription factor for organogenesis of the thyroid gland, kidney, and Müllerian system, and it also regulates Wilms tumor suppressor gene (WT1) expression. A total of 124 cases of ovarian carcinomas (84 serous papillary, 18 endometrioid, 12 mucinous, 10 clear cell) and 243 cases of invasive breast carcinomas (178 ductal, 65 lobular) were immunostained with Pax8 and WT1 by tissue microarrays to see the differential expression. Pax8 reaction was found in 108 of 124 ovarian carcinomas (87.1%) generally in diffuse staining, including 81 of 84 serous papillary carcinomas (96.4%), 16 of 18 endometrioid carcinomas (88.9%), 10 of 10 clear cell carcinomas (100%), and 1 of 12 mucinous carcinomas (8.3%), whereas WT1 expression was seen in 78 of 124 ovarian carcinomas (62.9%), including 73 of 84 serous papillary carcinomas (86.9%), and 5 of 18 endometrioid carcinomas (27.8%), with no expression in all 10 clear cell carcinomas and 12 mucinous carcinomas. All the mammary carcinomas were completely negative for Pax8, but WT1 expression was seen in 5 of 243 cases (2.1%). Pax8 is a useful marker in the differential diagnosis of ovarian and breast carcinomas, and it seems to be superior to WT1 for the diagnosis of all types of nonmucinous ovarian carcinomas, notably clear cell and endometrioid types where WT1 expression is generally negative or only focal.
Comparison of maximum-likelihood-based detection for two multirate access schemes for CDMA signals (1999)

Future wireless systems will need to accommodate information sources with different data rates. Direct-sequence code-division multiple-access (DS/CDMA) is a multiple access technique that is well suited to provide multirate access. Thus, in this paper, multirate communication systems are considered for the transmission of DS/CDMA wireless signals. Performance for maximum-likelihood-based detection is studied in the context of two multirate access methodologies: multicode access, where high data rate users multiplex their information streams onto multiple codes; and variable spreading length access where signature sequences of different lengths are assigned to users with different data rates. Various maximum-likelihood-based detection schemes for the variable spreading length system are considered as they can achieve near-optimal performance and thus provide reference points for comparison with suboptimal schemes. In addition, asymptotic multiuser performance measures are calculated and bounded to compare performance of the two systems.
Silicon Oxide Permeation Barrier Coating and Plasma Sterilization of PET Bottles and Foils (2009)

Abstract The results of silicon oxide permeation barrier coating and plasma sterilization are shown using a low‐pressure microwave plasma reactor system based on a Plasmaline antenna developed for the treatment of polyethylene terephthalate bottles and foils. The influence of the coating composition on the barrier properties is analyzed and a good correlation is found. The optimized barrier coatings are analyzed regarding coating defects, which are visualized by means of capacitively coupled oxygen plasma etching of the coated substrates. The capabilities of plasma sterilization are exemplarily demonstrated for spores of Bacillus atrophaeus allowing for a spore reduction according to today's regulations for aseptic food packaging.
The System Lead-Antimony—II. (1925)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe System Lead-Antimony—II.R. S. Dean, W. E. Hudson, and M. F. FoglerCite this: Ind. Eng. Chem. 1925, 17, 12, 1246–1247Publication Date (Print):December 1, 1925Publication History Published online1 May 2002Published inissue 1 December 1925https://pubs.acs.org/doi/10.1021/ie50192a016https://doi.org/10.1021/ie50192a016research-articleACS PublicationsRequest reuse permissionsArticle Views35Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Zero forcing equalization of multiuser time-varying nonlinear systems (2003)

Multiuser communication systems which experience intersymbol interference and nonlinearities can be modeled using the Volterra series. In this paper we consider the design of a linear multichannel zero forcing equalizer for a multiuser Volterra (nonlinear) system. Time-variations in the Volterra systems are modeled using basis expansions, and equivalent multiple-input time-invariant systems are derived. Equalizers are designed from the channel matrix and a training sequence, and complex exponential basis frequencies are estimated. Simulations demonstrate the effectiveness of the equalizer on a number of different systems.
Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246 (2018)

TP53 mutants (mutp53) are involved in the pathogenesis of most human cancers. Specific mutp53 proteins gain oncogenic functions (GOFs) distinct from the tumor suppressor activity of the wild-type protein. Tumor-associated macrophages (TAMs), a hallmark of solid tumors, are typically correlated with poor prognosis. Here, we report a non-cell-autonomous mechanism, whereby human mutp53 cancer cells reprogram macrophages to a tumor supportive and anti-inflammatory state. The colon cancer cells harboring GOF mutp53 selectively shed miR-1246-enriched exosomes. Uptake of these exosomes by neighboring macrophages triggers their miR-1246-dependent reprogramming into a cancer-promoting state. Mutp53-reprogammed TAMs favor anti-inflammatory immunosuppression with increased activity of TGF-β. These findings, associated with poor survival in colon cancer patients, strongly support a microenvironmental GOF role for mutp53 in actively engaging the immune system to promote cancer progression and metastasis.
DISCOUNTS FOR CASH IN RETAIL GASOLINE MARKETING (1992)

Before introducing cash discounting in retail gasoline markets, major oil companies offered proprietary credit cards as an unpriced service to their customers. This paper analyzes the origins of cash discounting in order to determine why oil companies introduced explicit pricing of the credit service in 1982 only to begin discouraging it by the end of the decade. Sharp increases in nominal interest rates and in the real price of gasoline between 1978–1982 spurred a rapid rise in the cost of financing accounts receivable. This increasing cost in part drove the initial decision to discount. By 1990 the discounting trend reversed as the costs of processing credit transactions and of the float associated with non‐revolving accounts receivable fell. Using station data from Delaware in 1983 and Washington in 1989, the paper also provides two separate estimations of the subsidy to credit buyers by cash buyers.
Non-Abelian Anyon Superconductivity (2007)

Non-Abelian anyons exist in certain spin models and may exist in quantum Hall systems at certain filling fractions. In this work, we studied the ground state of dynamical SU(2) level-kappa Chern-Simons non-Abelian anyons at finite density and no external magnetic field. We find that, in the large-kappa limit, the topological interaction induces a pairing instability and the ground state is a superconductor with d+id gap symmetry. We also develop a picture of pairing for the special value kappa=2 and argue that the ground state is a superfluid of pairs for all values of kappa.
Formaldehyde Levels and the Factors Affecting These Levels in Homes in Perth, Western Australia (2002)

Formaldehyde is a highly irritant gas commonly encoun tered in indoor environments. Domestic levels of formal dehyde may vary with building practices and climate and the aim of the present study was to investigate formalde hyde levels in 185 homes in Perth, Australia. The formal dehyde was monitored using a validated passive sam pling technique. Levels were measured in four rooms of each house (living room, kitchen and large and small bedrooms). In 160 homes the monitoring was repeated 4-7 months later in a different season to the original measurement. It was found that within homes there was no significant difference in formaldehyde concentrations measured in the four rooms. For the first sampling peri od, the geometric mean of the average household con centration (average of the four rooms) for all homes was 22.8 ppb and ranged from 3.0 to 92.3 ppb. Only the age of the house (p < 0.0001) and the season of monitoring (p < 0.0001) were significant predictors of indoor levels, high er levels in newer homes and in homes monitored in summer. Mean concentrations were lower during the fol low-up monitoring, but only in houses that were less than 10 years old or in houses that were initially moni tored in summer. Overall formaldehyde concentrations were low and rarely exceeded the Australian guideline level of 100 ppb. There seemed to be good inter-room mixing of formaldehyde within homes. Concentrations were significantly affected by season and age of the house.
Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts (2012)

p38 MAP kinase is known to be activated by cellular stress finally leading to cell cycle arrest or apoptosis. Furthermore, a tumour suppressor role of p38 MAPK has been proposed. In contrast, a requirement of p38 for proliferation has also been described. To clarify this paradox, we investigated stress- and mitogen-induced p38 signalling in the same cell type using fibroblasts. We demonstrate that - in the same cell line - p38 is activated by mitogens or cellular stress, but p38-dependent signalling is different. Exposure to cellular stress, such as anisomycin, leads to a strong and persistent p38 activation independent of GTPases. As a result, MK2 and downstream the transcription factor CREB are phosphorylated. In contrast, mitogenic stimulation results in a weaker and transient p38 activation, which upstream involves small GTPases and is required for cyclin D1 induction. Consequently, the retinoblastoma protein is phosphorylated and allows G1/S transition. Our data suggest a dual role of p38 and indicate that the level and/or duration of p38 activation determines the cellular response, i.e either proliferation or cell cycle arrest.
Efficient Memory Management for Servers (2006)

Modern SMP servers with large heaps provide new challenges for the design of suitable garbage collectors. Garbage collectors designed for client machines usually work in the so called stop-the-world (STW) manner. A STW collector stops all program threads while executing. Naive collectors employ only one of the available CPUs on an SMP. Naive STW collectors may lead to inefficient running times on servers, long pause times and poor CPU utilization. These problems can be solved by either executing the collector in a separate thread (or process) concurrently with the program threads, or by parallelizing the execution of the collection. We have designed and implemented several alternative collectors for server platforms. These collectors attempt to improve the garbage collection process in SMP platforms. In particular, we have focused on concurrent collectors and reference-counting collectors. We started by designing a mark-and-sweep on-the-fly algorithm based on the sliding-views mechanism of Levanoni and Petrank. This algorithm can also be used to infrequently collect garbage cycles in the reference-counting sliding-views collector. Next, we introduced the ageoriented collector, which exploits the generational hypothesis best when used with reference counting, to obtain highly efficient collection. In our third project, we proposed a new onthe-fly cycle collection algorithm to accompany the reference-counting sliding-views collector. In the fourth, we have inserted prefetch instructions into the reference-counting collector in order to hide (or decrease) cache miss stalls, and hence reduce the overhead imposed by a reference-counting collector. Finally, we studied ways to identify and eliminate wasteful use of the memory management subsystem by employing three patterns, when possible. 1 T ec hn io n C om pu te r Sc ie nc e D ep ar tm en t P h. D . T he si s P H D -2 00 610 2 00 6 Notations and Abbreviations AO Age Oriented GC Garbage Collection JVM Java Virtual Machine MS Mark and Sweep RC Reference Counting RVM Research Virtual Machine SMP Symmetric Multi-Processor STW Stop the World SVMS Sliding-Views Mark-and-Sweep SVRC Sliding-Views Reference-Counting TIB Type Information Block ZCT Zero Counts Table 2 T ec hn io n C om pu te r Sc ie nc e D ep ar tm en t P h. D . T he si s P H D -2 00 610 2 00 6
Microbial oxidation of amines. Distribution, purification and properties of two primary-amine oxidases from the yeast <i>Candida boidinii</i> grown on amines as sole nitrogen source (1981)

1. The yeast Candida boidinii was grown on glucose as carbon source with a range of amines and amino acids as nitrogen sources. Cells grown on amines contained elevated activities of catalase. If the amines contained N-methyl groups, formaldehyde dehydrogenase, formate dehydrogenase and S-formylglutathione hydrolase were also elevated in activity compared with cells grown on (NH(4))(2)SO(4). 2. Cells grown on all the amines tested, but not those grown on urea or amino acids, contained an oxidase attacking primary amines, which is referred to as methylamine oxidase. In addition, cells grown on some amines contained a second amine oxidase, which is referred to as benzylamine oxidase. 3. Both amine oxidases were purified to near homogeneity. 4. Benzylamine oxidase was considerably more stable at 45 and 50 degrees C than was methylamine oxidase. 5. Both enzymes had a pH optimum in the region of 7.0, and had a considerable number of substrates in common. There were, however, significant differences in the substrate specificity of the two enzymes. The ratio V/K(app.) (m) increased with increasing n-alkyl carbon chain length for benzylamine oxidase, but decreased for methylamine oxidase. 6. Both enzymes showed similar sensitivity to carbonyl-group reagents, copper-chelating agents and other typical ;diamine oxidase inhibitors'. 7. The stoicheiometry for the reaction catalysed by each enzyme was established. 8. The kinetics of methylamine oxidase were examined by varying the methylamine and oxygen concentrations in turn. A non-Ping Pong kinetic pattern with intersecting double-reciprocal plots was obtained, giving K(m) values of 10mum for O(2) and 198mum for methylamine. The significance of this unusual kinetic behaviour is discussed. Similar experiments were not possible with the benzylamine oxidase, because it seemed to have an even lower K(m) for O(2). 9. Both enzymes had similar subunit M(r) values of about 80000, but the benzylamine oxidase behaved as if it were usually a dimer, M(r) 136000, which under certain conditions aggregated to a tetramer, M(r) 288000. Methylamine oxidase was mainly in the form of an octamer, M(r) 510000, which gave rise quite readily to dimers of M(r) 150000, and on gel filtration behaved as if the M(r) was 286000.
VSIA: it's advantages from four different perspectives (2002)

VSIA is a new organization with a mission to develop specifications for the creation and integration of Virtual Chips, functional subsystems used in System ASICs. It is made up of EDA, semiconductor, IP development, and System companies. This paper describes the advantages and implications of VSIA from these four perspectives.
On Blockchain Enhanced Secure Network Coding for 5G Deployments (2018)

The fifth generation of mobile networks is rapidly evolving, fueled by the ever-growing mobile traffic over recent years. Ultra-reliable and low latency provisioning of services with ranging contextual parameters mapped to highly fluctuating levels of quality of service and quality of user experience, render the optimum operation point of the future networks unsustainable. Network coding is emerging once more as a potential key enabler for optimizing bandwidth requirements and energy consumption in highly dense mobile network environments. Nonetheless, network coding deployments still need to consider security vulnerabilities and their countermeasures, before they can be adapted as part of the emerging mobile network deployments. This paper studies the performance of random linear network coding for wireless mobile networks with an emphasis on pollution attacks while proposing a novel blockchain based message authentication scheme in order to minimize delays and signalling costs.
Active Surveillance of Candidemia, Australia (2006)

Population-based surveillance for candidemia in Australia from 2001 to 2004 identified 1,095 cases. Annual overall and hospital-specific incidences were 1.81/100,000 and 0.21/1,000 separations (completed admissions), respectively. Predisposing factors included malignancy (32.1%), indwelling vascular catheters (72.6%), use of antimicrobial agents (77%), and surgery (37.1%). Of 919 episodes, 81.5% were inpatient healthcare associated (IHCA), 11.6% were outpatient healthcare associated (OHCA), and 6.9% were community acquired (CA). Concomitant illnesses and risk factors were similar in IHCA and OHCA candidemia. IHCA candidemia was associated with sepsis at diagnosis (p<0.001), death <30 days after infection (p<0.001), and prolonged hospital admission (p<0.001). Non-Candida albicans species (52.7%) caused 60.5% of cases acquired outside hospitals and 49.9% of IHCA candidemia (p = 0.02). The 30-day death rate was 27.7% in those > or =65 years of age. Adult critical care stay, sepsis syndrome, and corticosteroid therapy were associated with the greatest risk for death. Systematic epidemiologic studies that use standardized definitions for IHCA, OHCA, and CA candidemia are indicated.
Carbenoxolone does not cross the blood brain barrier: an HPLC study (2006)

Thus, we conclude that, most likely, CBX does not penetrate the blood brain barrier and therefore recommend careful consideration in the manner of administration, when a central effect is desired.
<i>Morinda citrifolia</i>L.- (1993)

Based on literature and a field study, the use of Morinda citrifolia L. in the traditional medicine of Samoa (Western Polynesia) is given. Literature data on constituents and effectiveness is also included.
Peripheral neuropathy is associated with insulin resistance independent of metabolic syndrome (2015)

In metabolic syndrome, insulin resistance might play an important role in the development of peripheral neuropathy.
Expired hydrocarbons in patients with chronic liver disease. (1984)

Fifty patients with various types of liver disease and twenty-one healthy subjects were examined for lipoperoxidation in vivo by gaschromatographic assay of volatile hydrocarbons (ethane, ethylene, propane, n-butane, n-pentane) in breath gases. In 15 patients with alcoholic cirrhosis the amount of expired pentane was greater than in all the other groups examined. No significant increase of exhaled ethane, in contrast, was detected in the same patients. These results seem to indicate that pentane is a more sensitive index than ethane for ethanol-induced lipoperoxidation. This simple and non-invasive method opens up promising new opportunities for clarifying in humans, the role of lipoperoxidation in ethanol-induced liver damage, as well as in other chronic liver disease.