gebhart/patrepeval huggingface dataset:
EUROPEAN CONSENSUS ON THE MEDICAL MANAGEMENT OF ACUTE RADIATION SYNDROME AND ANALYSIS OF THE RADIATION ACCIDENTS IN BELGIUM AND SENEGAL (2010)

A European consensus concerning the medical management of mass radiation exposure was obtained in 2005 during a conference held by the European Group for Blood and Bone Marrow Transplantation, the Institute of Radioprotection and Nuclear Safety, and the University of Ulm. At the conference, a two-step triage strategy to deal with large masses of radiation-exposed patients was designed. The first step of this strategy concerns the first 48 h and involves scoring the patients exclusively on the basis of their clinical symptoms and biological data. This allows the non-irradiated bystanders and outpatient candidates to be identified. The remaining patients are hospitalized and diagnosis is confirmed after the first 48-h period according to the METREPOL (Medical Treatment Protocols for radiation accident victims) scale. This grades the patients according to the severity of their symptoms. It was also agreed that in the case of acute radiation syndrome (ARS), emergency hematopoietic stem cell (HSC) transplantation is not necessary. Instead, cytokines that promote hematological reconstruction should be administered as early as possible for 14-21 d. Crucial tests for determining whether the patient has residual hematopoiesis are physical dose reconstructions combined with daily blood count analyses. It was agreed that HSC transplantation should only be considered if severe aplasia persists after cytokine treatment. Two recent cases of accidental radiation exposure that were managed successfully by following the European consensus with modification are reviewed here. Thus, a European standard for the evaluation and treatment of ARS victims is now available. This standard may be suitable for application around the world.
Excretion of Radioactive Daidzein and Equol as Monosulfates and Disulfates in the Urine of the Laying Hen (1975)

The phytoestrogen, diadzein, was injected intramuscularly as [4-14-C]daidzein into two laying hens. The radioactive materials in the urine for the succeeding 23 (hen 1) or 14 (hen 2) days were fractionated on a DEAE-Sephadex column by a gradient of NaCl and the fractions thus separated were further analyzed by solvent partition, susceptability to enzymic cleavage and thin-layer chromatography. The sic following components were identified and quantitated: [14-C]diadzein, [14-C]equol, [14-C]diadzein monosulfate, [14-C]equol monosulfate, [14-C]diazein disulfate, and [14-C]equol disulfate. The urine from hen 2 yielded also the sulfate of an unidentified conversion product of [14-C]daidzein. Repeared tests for glucuronides of [14-C]daidzein or its conversion products gave negative results, excluding the possibility that any appreciable proportion of the radioactivity in the urine was in the form of beta-glucuronide. It is concluded that the diadzein and the equol excretion in the urine of the laying hen are present for the most part as monosulfates and disulfates.
Murasaki: A Fast, Parallelizable Algorithm to Find Anchors from Multiple Genomes (2010)

Murasaki provides an open source platform to take advantage of long patterns, cluster computing, and novel hash algorithms to produce accurate anchors across multiple genomes with computational efficiency significantly greater than existing methods. Murasaki is available under GPL at http://murasaki.sourceforge.net.
Next hop resolution using classical IP over ATM (2002)

In principle, more than one routers are intervened between different IP subnets. IETF RFC1577 "Classical IP and ARP over ATM", which is specified to provide IP services on ATM network, also requires that the router be used between different LISs (Logical IP subnet). However, the intervention of the router is not always an effective solution on ATM network. If there is a direct virtual channel connection between two endpoints on ATM network, they can exchange their information directly without the help of routers. Actually, some groups of IETF and ATM Forum are looking on such tasks. As the results, NHRP (Next Hop Resolution Protocol) or MPOA (Multi-Protocol Over ATM) are being drafted. However, since those protocols are too heavy and complicate, it is not easy to implement. In this paper, we propose a simple efficient solution for inter-LIS communication. Our solution is exactly compatible with RFC1577. We describe how RFC1577 can be used to provide inter-LIS communications and introduce our prototype systems and test-bed network.
Carrier recovery and inter‐burst interference in a symbol‐synchronous tdma system (1991)

Abstract ESA is studying future communications satellite systems involving switching and processing on board the satellite. One concept uses a symbol‐synchronous MF‐TDMA system with very short data bursts. This paper investigates QPSK carrier phase estimation for coherent demodulation in such a system. The Viterbi and Viterbi algorithm is used to produce one phase estimate separately for each data burst. The algorithm and its properties are reviewed and computer simulation results are presented to show its performance. It offers excellent performance under the conditions planned for the MF‐TDMA system and is robust against distortions and interference. One potential problem in such a system, with no interburst guard‐time and possible level differences between adjacent bursts, is interburst interference. It is found that clear‐weather level differences of several dB can be tolerated easily. Atmospheric attenuation of the wanted burst may result in major level differences between adjacent bursts, but the interburst interference itself does not increase with respect to the thermal noise environment and so does not contribute any new problems. Any requirement for power control, for instance, will be determined by considerations of noise rather than interference. The burst timing accuracy in such a system is set by normal intersymbol interference considerations, rather than by the interburst interference or the needs of the phase estimator.
Evaluation of long-term safety and clinical benefit of terodiline in women with urgency/urge incontinence. A multicentre study. (1984)

Terodiline is a secondary amine with anticholinergic and calcium antagonistic properties. The drug has been shown in controlled studies to be effective in patients with motor urge incontinence. In order to evaluate safety and clinical benefits of terodiline during long-term therapy in women with urgency/urge incontinence, a 6-month study has been performed. The study was designed as an open multicentre study with a run-in period and assessments after 3 and 6 months treatment. One hundred patients with a mean age of 48 years (range 18-78) were included. The daily dose was 50 mg, given as 25 mg in the morning and 25 mg at night. The safety was evaluated by recording of adverse reactions and measurements of haematology (B-Hb, B-erythrocytes, B-leukocytes, B-thrombocytes), liver function (S-ALAT, S-ASAT, S-ALP), kidney function (S-creatinine), ESR, heart rate and blood pressure. Clinical benefits were assessed by changes in micturition patterns, cystometry and patient preferences. Ninety-one patients were evaluated after 3 months and seventy after both 3 and 6 months. Terodiline was in most patients well tolerated and adverse reactions, usually those to be expected from the pharmacological effects of the drug, caused withdrawals in 12 patients. Mean levels of all variables on clinical chemistry were well within the normal range. No significant changes were seen except for a small increase in B-thrombocytes, S-creatinine and ESR. No significant changes in heart rate or blood pressure occurred except for a small but statistically significant increase (about 2 mmHg) in resting diastolic blood pressure after 6 months. A statistically significant decrease of voluntary as well as involuntary micturitions was seen. The number of voluntary micturitions decreased from a mean of 10.8 during run-in by 2.4 per day (p less than 0.01) during the first period and by 2.5 per day (p less than 0.01) during the whole 6-month therapy. Involuntary micturitions decreased by 1.3 from 2.7 per day (p less than 0.01) after 3 months and by 1.1 per day (p less than 0.01) after 6 months. Both bladder volume at first sensation to void and the maximum cystometric bladder capacity increased significantly from 134 ml by 56 (p less than 0.01) and 63 ml (p less than 0.01) after 3 and 6 months and from 252 ml by 54 (p less than 0.01) and 66 ml (p less than 0.01) after 3 and 6 months, respectively. No significant changes in bladder pressure or residual urine were shown.(ABSTRACT TRUNCATED AT 400 WORDS)
Spyglass: fast, scalable metadata search for large-scale storage systems (2009)

As storage systems reach the petabyte scale, it has become increasingly difficult for users and storage administrators to understand and manage their data. File metadata, such as inode and extended attributes are a valuable source of information that can aid in locating and identifying files, and can also facilitate administrative tasks, such as storage provisioning and recovery from backups. Unfortunately, most storage systems have no way to quickly and easily search file metadata at large scale. To address these issues, we developed Spyglass, a indexing system that efficiently gathers, indexes and queries file metadata in large-scale storage systems. Our analysis of file metadata from real-world workloads showed that metadata has spatial locality in the storage namespace and that the distribution of metadata is highly skewed. Based on these findings, we designed Spyglass to use index partitioning and signature files to quickly prune the file search space. We also developed techniques to efficiently handle index versioning, facilitating both fast update and queries across historical indexes. Experiments on systems with up to 300 million files show that the Spyglass prototype is as much as several thousand times faster than current database solutions while requiring only a fraction of the space. 1
Non-steroidal anti-inflammatory drugs for postoperative pain relief (1994)

Non-steroidal anti-inflammatory drugs (NSAIDs) block both cyclo-oxygenase-1 and −2. The ratio of potency against cylco-oxygenase-1: potency against cyclo-oxygenase-2 explains the profile of efficacy and side effects of these agents. NSAIDs inhibit nociceptive transmission through C-fibres, but presumably not through Adelta-fibres. They relieve pain and display synergistic effects with opioids when administered intrathecally. The spectre of side effects was in favour of NSAIDs when compared with opioids in only a few controlled studies. A pre-emptive effect of NSAIDs on postoperative pain is still discussed. NSAIDs should be used with caution in the elderly, in the intensive care unit, and in patients with bronchial asthma, reduced renal function, or impaired gastroduodenal mucosal protection.
Nanoduct Sweat Conductivity Measurements in 2664 Patients: Relationship to Age, Arterial Blood Gas, Serum Electrolyte Profiles and Clinical Diagnosis (2013)

Patients suspected to have CF can be screened using the Nanoduct(®) conductivity device in non-qualified centers.
A ruthenium tris(diimine) complex with three different ligands (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA ruthenium tris(diimine) complex with three different ligandsRandolph P. Thummel, Francois Lefoulon, and Sara ChirayilCite this: Inorg. Chem. 1987, 26, 18, 3072–3074Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://doi.org/10.1021/ic00265a031RIGHTS & PERMISSIONSArticle Views325Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (433 KB) Get e-Alerts Get e-Alerts
Optical Magnetometry with Nitrogen-Vacancy Centers in Diamond - eScholarship (2011)

Precision measurement of magnetic fields is at the heart of many important analytic techniques in materials, geology, biology, medicine, security, space, and the physical sciences. These applications require operation under a wide range of specifications regarding sensitivity, spatial resolution, bandwidth, scalability, and temperature. In this work we have developed the enabling technology for magnetometers based on nitrogen-vacancy (NV) defects in diamond which promise to cover a wider portion of this parameter space than existing sensors. We have studied how to prepare diamond material optimized for magnetometry, and we observed the basic optical and spin properties of the NV centers. Using a novel scheme inspired by new information about NV centers gathered from these studies, we constructed a sensor which improved on the state-of-the-art in a number of areas. Finally, we outline a plan for improving these sensors to study micro- and nano-scale magnetic phenomena currently inaccessible using existing technology.
Cell type discovery and representation in the era of high-content single cell phenotyping (2017)

The advent of high-throughput/high-content single cell technologies is leading to an explosion in the number of distinct cell types being identified. It will be critical for the bioinformatics community to develop and adopt data standard conventions that will be compatible with these new technologies and support the data representation needs of the research community. The proposals enumerated here will serve as a useful starting point to address these challenges.
Response of the human gut and saliva microbiome to urbanization in Cameroon (2020)

Urban populations from highly industrialized countries are characterized by a lower gut bacterial diversity as well as by changes in composition compared to rural populations from less industrialized countries. To unveil the mechanisms and factors leading to this diversity loss, it is necessary to identify the factors associated with urbanization-induced shifts at a smaller geographical scale, especially in less industrialized countries. To do so, we investigated potential associations between a variety of dietary, medical, parasitological and socio-cultural factors and the gut and saliva microbiomes of 147 individuals from three populations along an urbanization gradient in Cameroon. We found that the presence of Entamoeba sp., a commensal gut protozoan, followed by stool consistency, were major determinants of the gut microbiome diversity and composition. Interestingly, urban individuals have retained most of their gut eukaryotic and bacterial diversity despite significant changes in diet compared to the rural areas, suggesting that the loss of bacterial microbiome diversity observed in industrialized areas is likely associated with medication. Finally, we observed a weak positive correlation between the gut and the saliva microbiome diversity and composition, even though the saliva microbiome is mainly shaped by habitat-related factors.
Comparative studies on drug‐receptor binding of phenylethylamine derivatives using calculated group contribution constants (1981)

Abstract Group contribution constants of phenylethylamine derivatives were calculated using a modified version of the Free‐Wilson approach and data published on group contributions were also collected. The biological activity indices used to extract these contributions are the inhibition of phenylethanolamine N ‐methyl transferase, inhibition of norepinephrine uptake, dopamine β‐hydroxylase substrate activity, phenylethanolamine N ‐methyl transferase substrate activity, and antagonism to the pressor activity of epinephrine. The different sets of calculated group contributions were compared. Correlation could be demonstrated between sets of group contributions, except those extracted from the antipressor activity data. It is concluded that the interaction mechanism between the receptor site and the aromatic ring might be similar in the systems considered. Methylation of the nitrogen atom appearently does not cause any change in specificity at the molecular level.
Numerical coarsening of inhomogeneous elastic materials (2009)

We propose an approach for efficiently simulating elastic objects made of non-homogeneous, non-isotropic materials. Based on recent developments in homogenization theory, a methodology is introduced to approximate a deformable object made of arbitrary fine structures of various linear elastic materials with a dynamicallysimilar coarse model. This numerical coarsening of the material properties allows for simulation of fine, heterogeneous structures on very coarse grids while capturing the proper dynamics of the original dynamical system, thus saving orders of magnitude in computational time. Examples including inhomogeneous and/or anisotropic materials can be realistically simulated in realtime with a numerically-coarsened model made of a few mesh elements.
Cylindrical linear stepper motor (1994)

The subject of this paper is a novel form of linear stepper motor based purely on variable-reluctance principle, for applications requiring controlled low-speed linear motion. The motor to some extent represents the linear counterpart of the rotary variable-reluctance stepper motor and it is distinguished by the simplicity of construction, arising from its cylindrical form, which form the mechanical point of view benefits from convenience of manufacturing, assembly and extension. The main features of its magnetic configuration are: (i) each phase set forms an independent magnetic circuit and (ii) each phase winding consists of a single coil which is surrounded by a magnetic core. The power electronic switching circuits and control strategies used in the rotary doubly-salient variable-reluctance counterpart (both the stepper and switched reluctance motor type) can also be used here. A high ratio of 'static thrust/mass' has been obtained with an experimental prototype, which indicates a potential of this type of linear motor.
A Storage- and Power-Efficient Range-Matching TCAM for Packet Classification (2006)

A range-matching TCAM using the proposed range-matching cell increases storage efficiency by up to 2.5 times compared to a conventional TCAM. In addition, charge recycling with the proposed static TCAM cell can reduce the search-line power. The 512 times 144b prototype chip, fabricated in a 1.2V 0.13μm CMOS process, achieves a 4.8ns search time at 0.59fJ/b/search
Order-continuous functions and order-connected spaces (1970)

We introduce and compare four procedures for defining the order-continuity of a function from one topological ordered space into another, where each reduces to the usual conception when the orderings of the two spaces are trivial. Chiefly for the purposes of this comparison, we use the idea of an ‘order-connected’ space, and in the course of investigating under which types of order-continuous functions this property is preserved, we are helped in assessing their relative importance.
Organocatalytic Enantioselective aza‐Michael Additions of N‐Heterocycles to α,β‐Unsaturated Enones (2010)

Abstract A procedure for enantioselective organocatalytic conjugate additions of a variety of N‐heterocycles to α,β‐unsaturated enone systems is presented. The reactions are efficiently catalyzed by salts of 9‐amino‐9‐deoxy‐epiquinine ( 3d ). Cyclic, acyclic, and aromatic enones can be used in reactions with 1 H ‐benzotriazole ( 1a ) or 5‐phenyltetrazole derivatives 12 , providing the Michael addition products in high yields and with good to excellent enantioselectivities.
Solar power tower as heat and electricity source for a solid oxide electrolyzer: a case study (2015)

High-temperature steam electrolysis (HTSE) consists of the splitting of steam into hydrogen and oxygen at high temperature in solid oxide electrolyzers. Performing the electrolysis process at high temperatures offers the advantage of achieving higher efficiencies as compared to the conventional water electrolysis. Furthermore, this allows the direct use of process heat to generate steam. This paper is related to the FCH JU (Fuel Cells and Hydrogen Joint Undertaking) project ADEL (ADvanced ELectrolyser For hydrogen Production with Renewable Energy Sources), which investigates different carbon-free energy sources to be coupled to the HTSE process. Renewable energy sources are able to provide the high-temperature steam electrolysis (HTSE) process with heat and power. This paper investigates the capability of Concentrating Solar Power (CSP) technologies to provide the HTSE process with the necessary energy demand. The layout of the plant is shown in the following figure. The design of commercial-scale high-temperature steam electrolysis has been carried out. The HTSE plant is coupled to an air cooled solar tower. The configuration and the operating parameters of the solar tower are based on those of the solar tower of Jülich (Germany), which is operated by DLR. This paper presents the results of process analysis performed to evaluate the hydrogen production from a HTSE plant coupled to an 80MWth air solar tower. Additionally, the dynamic behavior of the system during energy fluctuations has been analyzed. The receiver-to-hydrogen efficiency (based on the Higher Heating Value of hydrogen) is 26% at a hydrogen production rate of 680 kg/h in steady-state operation. The overall solar-to-hydrogen efficiency is calculated to be at 18%. Moreover, the analysis under transient conditions shows that a steady-state operation of the plant is only possible for 8 h. Copyright © 2015 John Wiley & Sons, Ltd.
A latency-conscious SMT branch prediction architecture (2004)

Executing multiple threads has proved to be an effective solution to partially hide latencies that appear in a processor. When a thread is stalled because of a long-latency operation is being processed, such as a memory access or a floating-point calculation, the processor can switch to another context so that another thread can take advantage of the idle resources. However, fetch stall conditions caused by a branch predictor delay are not hidden by current simultaneous multithreading (SMT) fetch designs, causing a performance drop due to the absence of instructions to execute. In this paper, we propose several solutions to reduce the effect of branch predictor delay in the performance of SMT processors. Firstly, we analyse the impact of varying the number of access ports. Secondly, we describe a decoupled implementation of an SMT fetch unit that helps to tolerate the predictor delay. Finally, we present an interthread pipelined branch predictor, based on creating a pipeline of interleaved predictions from different threads. Our results show that, combining all the proposed techniques, the performance obtained is similar to that obtained using an ideal, 1-cycle access branch predictor.
LiNbO3 modulator for binary and multilevel polarization modulation (1994)

The modulation of the state of polarization (SOP) of light has been recently proposed for transmission of information on optical fibers.1-4 Polarization-shift keying (POLSK) is suitable for both coherent and direct-detection (DD) systems. In either case, both binary and multilevel schemes are possible.