gebhart/patrepeval huggingface dataset:
The stress assisted evolution of point and extended defects in silicon (1997)

As semiconductor devices are scaled to sub-micron dimensions, they are becoming more complex in geometry and materials. Stress related problems are therefore pervasive and critical in ultralarge scale integrated technology. High levels of stress can cause severe degradation of device characteristics by generating and propagating dislocations in the silicon substrate. Furthermore, stress in the silicon substrate can cause dopant redistribution to an extent it can no longer be neglected when designing scaled devices. In this study the effect of stress, generated from patterned nitride stripes on silicon, on the diffusion of phosphorus and evolution of ion-implanted dislocation loops is investigated. Phosphorus displays retarded diffusion, while the dislocation loops are smaller and less dense in the compressive regions under the nitride film.
Eremophilenolides and Other Constituents from the Roots of<i>Ligularia sagitta</i> (2003)

Chemical investigation of the roots of Ligularia sagitta has resulted in the characterization of six eremophilenolides 6beta,8beta-dimethoxy-10beta-hydroxyeremophil-7(11)-en-12,8alpha-olide (1), 6beta-angeloyloxy-10beta-hydroxy-8beta-methoxyeremophil-7(11)-en-12,8alpha-olide (2), 6beta-(2'-methylbutanoyloxy)-10beta-hydroxy-8beta-methoxyeremophil-7(11)-en-12,8alpha-olide (3), 6beta-angeloyloxy-10beta-hydroxy-8alpha-methoxyeremophil-7(11)-en-12,8beta-olide (4), 6beta-(2'-methylbutanoyloxy)-10beta-hydroxy-8alpha-methoxyeremophil-7(11)-en-12,8beta-olide (5) and 8beta,10beta-dihydroxy-6beta-methoxyeremophil-7(11)-en-12,8alpha-olide (6), together with one monoterpene (3 R,4 R,6 S)-3,6-dihydroxy-1-menthene (7), two triterpenes lupeol (8) and ursolic acid (9), and beta-sitosterol (10). The structures of five new constituents (1-5) were elucidated by spectroscopic methods including 2D-NMR experiments. The compounds 1, 5 and 7 showed antibacterial activity by being assayed against Staphylococcus aureus, Bacillus subtilis and Escherichia coli.
An adaptive supramolecular organic framework for highly efficient separation of uranium via an in situ induced fit mechanism (2015)

The as-synthesized adaptive supramolecular organic framework (MA–TMA) filled with abundant hydrogen-bonded N-/N and N-/O-heterocyclic motifs exhibits remarkable ability for highly efficient separation of uranium <italic>via</italic> an <italic>in situ</italic> “induced-fit” ion recognition mechanism.
Highly sensitive graphene biosensors based on surface plasmon resonance (2010)

A surface plasmon resonance (SPR) based graphene biosensor is presented. It consists of a graphene sheet coated above a gold thin film, which has been proposed and experimentally fabricated recently [ChemPhysChem 11, 585 (2010)]. The biosensor uses attenuated total reflection (ATR) method to detect the refractive index change near the sensor surface, which is due to the adsorption of biomolecules. Our calculations show that the proposed graphene-on-gold SPR biosensor (with L graphene layers) is (1 + 0.025 L) x gamma (where gamma > 1) times more sensitive than the conventional gold thin film SPR biosensor. The improved sensitivity is due to increased adsorption of biomolecules on graphene (represented by the factor gamma) and the optical property of graphene.
I. Zur Kenntnis der menschlichen Schweißdrüsen (1925)

Research Articles| October 14 2009 I. Zur Kenntnis der menschlichen Schweißdrüsen Subject Area: Dermatology , Immunology and Allergy Felix Pinkus Felix Pinkus Aus der dermatologischen Abteilung des städt. Krankenhauses Altona [Prof. Dr. C. Bruck] und dem städt. Untersuchungsamt [Oberarzt Dr. Zeiβler] Search for other works by this author on: This Site PubMed Google Scholar Dermatology (2004) 43 (5-6): 253–259. https://doi.org/10.1159/000250723 Article history Published Online: October 14 2009 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Felix Pinkus; I. Zur Kenntnis der menschlichen Schweißdrüsen. Dermatology 1 July 2004; 43 (5-6): 253–259. https://doi.org/10.1159/000250723 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsDermatology Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 1925Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Monte Carlo simulation using Excel(R) spreadsheet for predicting reliability of a complex system (2002)

A technique for performing Monte-Carlo simulation using an Excel spreadsheet has been developed. This technique utilizes the powerful mathematical and statistical capabilities of Excel. The functional reliability block diagram (RBD) of the system under investigation is first transformed into a table in an Excel spreadsheet. Each cell within the table corresponds to a specific block in the RBD. Formulae for failure times entered into these cells are in accordance with the failure time distribution of the corresponding block and can follow exponential, normal, lognormal or Weibull distribution. The Excel pseudo random number generator is used to simulate failure times of individual units or modules in the system. Logical expressions are then used to determine system success or failure. Excel's macro feature enables repetition of the scenario thousands of times while automatically recording the failure data. Excel's graphical capabilities are later used for plotting the failure probability density function (PDF) and cumulative distribution function (CDF) of the overall system. The paper discusses the results obtainable from this method such as reliability estimate, mean and variance of failures and confidence intervals. Simulation time is dependent on the complexity of the system, computer speed, and the accuracy desired, and may range from a few minutes to a few hours.
Development of an Actively Regenerating DPF System for Retrofit Applications (2006)

<div class="htmlview paragraph">Diesel Particulate Filters (DPFs) such as the Continuously Regenerating Technology (CRT<sup>®</sup>) particulate filters are known to be highly effective in reducing PM emissions from diesel engines. Passive DPFs such as the CRT filter operate by collecting soot in the filter and subsequently oxidizing this soot in the presence of NO<sub>2</sub> generated by an upstream Diesel Oxidation Catalyst (DOC). Both the NO<sub>2</sub> generation and subsequent soot oxidation reactions require a certain minimum exhaust temperature. In addition, the engine out NO<sub>x</sub> to PM ratio is also critical for continuous and successful regeneration of the filter. However, these criteria may not always be met, particularly on low temperature applications such as refuse vehicles and newer low NO<sub>x</sub> (2.5 g/bhp-hr NO<sub>x</sub>) engines.</div> <div class="htmlview paragraph">This paper discusses the development of an actively regenerating diesel particulate filter (ACR-DPF) system for retrofit applications on heavy duty diesel vehicles. The system is designed using a basic CRT filter system with an integrated fuel injection based active regeneration system. The active regeneration system utilizes atomized diesel fuel that is injected upstream of the CRT to produce an exothermic reaction across the DOC. This increases the exhaust temperature, which allows for periodic O<sub>2</sub>-based soot oxidation in the filter, in addition to normal NO<sub>2</sub>-based regeneration.</div> <div class="htmlview paragraph">ACR-DPF development included the evaluation of various trigger strategies for regeneration, the development of fuel injection maps, and optimization of the regeneration strategy for minimum HC slip. The performance was evaluated both in engine dynamometer tests and on-road field trials. Transient test cell data, along with data from an on-road demonstration on refuse vehicles at Department of Sanitation in New York and transit buses in Sweden is presented.</div>
Response time of a liquid crystal image transducer (1978)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Bernard W. Joseph and Aaron D. Gara, "Response time of a liquid crystal image transducer," Appl. Opt. 17, 1987_2-1989 (1978) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Internet X.509 Public Key Infrastructure Certificate Request Message Format (CRMF) (2005)

This document describes the Certificate Request Message Format (CRMF).
This syntax is used to convey a request for a certificate to a
Certification Authority (CA), possibly via a Registration Authority
(RA), for the purposes of X.509 certificate production. The request
will typically include a public key and associated registration
information.
Computation of Bit-Error Rate of Various Heterodyne and Coherent-Type Optical Communication Schemes (1981)

Article Computation of Bit-Error Rate of Various Heterodyne and Coherent-Type Optical Communication Schemes was published on September 1, 1981 in the journal Journal of Optical Communications (volume 2, issue 3).
Trade Blocs and Marketing: (1992)

This paper discusses the emergence and present role of trade blocs in terms of their implications for marketing strategy and research. The economic integration, international marketing, and related literatures serve as the basis for an analysis of the antecedents and growth determinants of trade blocs and a tentative typology and overview of existing trade-oriented country groupings. The analysis suggests that trade bloc-specific implications and strategies differ from global or national ones, but also from those related to regions where no formal trade association is present.
P3‐452: Bayesian cognitive models increase sensitivity for detecting treatment effect: Analysis of Flurizan phase III trial data (2010)

The Myriad, randomized, double-blind, placebo-controlled phase 3 trial in mild Alzheimer's disease (AD) demonstrated no difference in ADAS-Cog scores over 18 months between placebo and Flurizan groups, although change in severity using the CDR sum of boxes score favored placebo. These results may be explained by various factors. In particular, we examined whether parameters of underlying cognitive components of verbal memory performance could improve detection of treatment effects. We also examined whether shuffling vs. fixing the order of word presentation during learning trials affected wordlist memory (WLM) performance. MCI Screen (MCIS) and ADAS-Cog WLM task item responses were available for 14 patients (6 Flurizan, 8 placebo) in the Myriad trial. Graphical hierarchical Bayesian analysis (GHBA) combined with a cognitive processing model was used to estimate primacy and recency parameters of encoding and retrieval during recall trials for placebo and treatment groups. The parameters were adjusted for effects of number of previous WLM assessments, and test used. For both WLM tests, the only parameter that distinguished treatment groups was the primacy parameter for delayed recall, which declined significantly less for placebo than for Flurizan. The MCIS was more 39% more sensitive than the ADAS-Cog WLM test in disciminating placebo from Flurizan treatment effects. 1. GHBA combined with cognitive processing models detected a Flurizan-placebo treatment difference not previously detected by the full ADAS-Cog battery in the Myriad phase 3 study. The primacy parameter for delayed recall is the key discriminator. 2. Treatment effect on WLM performance favored placebo, which is consistent with the Myriad phase 3 study finding in which treatment effect on severity also favored placebo. 3. The MCIS is more sensitive than ADAS-Cog WLM test in detecting treatment effect. The full ADAS-Cog may not be appropriate for clinical trials of milder AD stages.
The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex<i>trans</i>-[Pt(NH<sub>3</sub>)<sub>2</sub>(phenanthridine)Cl]NO<sub>3</sub> (2018)

A trans-DDP based monofunctional phenanthridine Pt(ii) complex was synthesized and characterized. Its anticancer activity was studied in vitro on a panel of human cancer cell lines and mouse intestinal cancer organoids. This complex displays significant antitumor properties, with a different spectrum of activity than that of classic bifunctional cross-linking agents like cisplatin.
Effects of Epidermal Growth Factor and Estrogen on the Regulation of the HMG-I/Y Gene in Human Mammary Epithelial Cell Lines (1997)

Members of the HMG-I/Y family of high-mobility-group chromatin proteins have been demonstrated to regulate gene expression in human cells in vivo. They are thought to function as gene regulatory molecules by acting as architectural transcription factors that modulate DNA and/or chromatin structure. Numerous studies have indicated that elevated HMG-I/Y gene expression is directly correlated with more advanced cancers and with increased metastatic potential. The inducible expression of the HMG-I/Y gene was studied in two human mammary epithelial cell lines, MCF7 and Hs578T, in the presence, or absence, of either 17 beta-estradiol or epidermal growth factor (EGF). Northern blot analysis indicated that there was no increase in HMG-I/Y mRNA in the nonmetastatic MCF7 cells when they were treated with either 17 beta-estradiol or EGF. In contrast, in the highly metastatic Hs578T cell line, there is a dramatic induction of HMG-I/Y mRNA expression of up to 23-fold when the cells are treated with EGF. mRNA primer extension analysis indicated that only two (of the possible four different) transcription initiation start sites in the HMG-I/Y gene are induced by EGF treatment of the Hs578T cells. Additional experiments demonstrated that in both epithelial cell types HMG-I/Y mRNAs are very stable (tl/2 of approximately 30 hr) and that in the Hs578T cells treated with EGF the cellular concentrations of the HMG-I/Y proteins increase concurrently with the induced mRNA levels. Given that HMG-I/Y proteins are regulators of gene activity whose elevated in vivo concentrations are known to be correlated with increased metastatic potential, these data demonstrating an EGF-induced over-expression of HMG-I/Y in the highly metastatic Hs578T, but not in the nonmetastatic MCF7cells, may have important implications concerning the cellular mechanisms involved in the progression of mammary epithelial tumors.
Preparation and Characterisation of Super‐Hydrophobic Surfaces (2010)

The interest in highly water-repellent surfaces has grown in recent years due to the desire for self-cleaning surfaces. A super-hydrophobic surface is one that achieves a water contact angle of 150 degrees or greater. This article explores the different approaches used to construct super-hydrophobic surfaces and identifies the key properties of each surface that contribute to its hydrophobicity. The models used to describe surface interaction with water are considered, with attention directed to the methods of contact angle analysis. A summary describing the different routes to hydrophobicity is also given.
Seismic multi-attribute analysis for lithology discrimination in Ganso Field, Oficina Formation, Venezuela (2005)

Even extensively drilled and supposedly well-understood fields have the capacity to surprise and challenge the reservoir modeling. This paper describes the unexpected discovery of a new reservoir based on the quantitative seismic attribute analysis performed to identify the target reservoir sand and determine a development strategy for the reservoir. While drilling a fairly routine development well in Ganso Field in the Oficina Basin of eastern Venezuela, ENI Dación discovered a new shallow accumulation, reservoired in high-quality channel facies sandstone that was 30 ft thick and full of relatively light oil. The reservoir flowed at the excellent rate of 950 b/d with 0% watercut on testing. The unexpected element of this discovery was that the accumulation was found with the landing section of a horizontal well targeting a deeper level, and the sand was completely absent in the pilot hole some 120 m away (Figure 1).
Sugar Metabolism in Developing Kernels of Starch-Deficient Endosperm Mutants of Maize (1990)

Sugar metabolism in kernels of starch-deficient endosperm mutants of maize (Zea mays L.) was examined to determine how single locus mutations of carbohydrate metabolism affect carbohydrate metabolism as a whole. Activities of 14 enyzmes were measured in extracts from endosperms from isogenic lines of normal, shrunken, shrunken-2, shrunken-4, brittle-1, and brittle-2 maize in an OH43 background. Nearly every enzyme activity examined was affected in some or all of the mutants. Sucrose synthase and aldolase activities were lower in all mutants compared to normal. ADP-Glc pyrophosphorylase activity in immature kernels was much higher in brittle endosperms than in normal, but absent in brittle-2 and shrunken-2 endosperms. The activity in those genotypes exhibiting activity was positively correlated with sucrose concentration in the kernels. Sucrose may be modulating the coarse control of ADP-Glc pyrophosphorylase activity by affecting the genetic transcription of message for this enzyme. Sorbitol dehydrogenase activity was negatively correlated with its substrate, fructose, supporting the hypothesis that sorbitol dehydrogenase converts fructose produced during sucrose degradation into sorbitol. Glucokinase activity was positively correlated with mature kernel dry weight. This supports the hypothesis that glucokinase activity may limit sucrose utilization. Shrunken-4 extracts had lower activities for a number of enzymes, supporting the view that this mutant may have an impediment to protein synthesis. Elevated sucrose levels were evenly distributed throughout 20-day postpollination shrunken-2 kernels, whereas a sucrose concentration gradient existed in normal kernels between the basal region and the upper endosperm. This gradient is apparently generated by the utilization of sugars and may facilitate the movement of sugars into developing corn kernels.
Tracking: a method for structural characterization of grains in powders or polycrystals (2001)

A method is presented for fast and non-destructive characterization of the individual grains inside bulk materials (powders or polycrystals). The positions, volumes and orientations of hundreds of grains are determined simultaneously. An extension of the rotation method is employed: a monochromatic beam of high-energy X-rays, focused in one dimension, impinges on the sample and the directions of the diffracted beams are traced by translation of two-dimensional detectors. Algorithms suitable for on-line analysis are described, including a novel indexing approach, where the crystal symmetry is used directly by scanning in Euler space. The method is verified with a simulation of 100 grains.
Constitutive Expression and Costimulatory Function of LIGHT/TNFSF14 on Human Melanoma Cells and Melanoma-Derived Microvesicles (2005)

Neoplastic cells are thought to have defective expression of costimulatory molecules. However, in this study, we show that human melanoma cells express LIGHT/TNFSF14, a ligand of herpesvirus entry mediator on T cells and of lymphotoxin beta receptor on stromal cells. In vitro, melanoma cells stained for LIGHT in the intracellular compartment, with weak or negative cell surface expression. However, LIGHT was expressed on tumor-derived microvesicles released from melanoma cells. In vivo, LIGHT was found in metastatic lesions, and the extent of lymphotoxin beta receptor expression on the stromal cells was significantly associated with a "brisk" T-cell infiltrate in the neoplastic tissue. In the lesions with a brisk T-cell infiltrate, stromal cells surrounding the tumor also stained for the T-cell attractant chemokine CCL21. The intratumoral T lymphocytes frequently expressed herpesvirus entry mediator and were characterized by a differentiated phenotype. Coculture of lymphocytes with LIGHT(+) melanoma-derived microvesicles or even with LIGHT(+) melanoma cells in the presence of interleukin-2 costimulated LIGHT-dependent CD3(+)CD8(+) T-cell proliferation. However, lymphocyte coculture with LIGHT(+) microvesicles in the presence of interleukin-2 was also associated with an apoptotic response as documented by increased binding of Annexin V by CD3(+)CD8(+) T cells. These data suggest that LIGHT constitutively expressed in human melanoma cells and microvesicles may contribute to regulate T-cell responses to tumor cells.
Combustión de excrementos. Una aproximación experimental (2016)

La Revista Historia Autónoma es una publicación semestral de investigación histórica donde tienen cabida todas las ciencias afines a la Historia. Es de periodicidad semestral, online, digital y de acceso abierto.