gebhart/patrepeval huggingface dataset:
Improvement of Boss Tower for Single Ball Swaging in Hard Disk Drive (2012)

Abstract- Ball swaging is a material process used to assemble a boss tower and an arm aperture. A swage ball is inserted into the boss tower to swage and couple two components. The swage ball has a larger diameter than an inner diameter of the boss tower, applies a compression force to the inner surface of the boss tower to hold both components together with adequate holding force and without damaging the boss tower. This study proposes a new design of the boss tower by relief ring width optimization. It reduces the arm tip deformation while avoiding HSA resonance and allows similar swaging quality by using single ball. The 3-D FE method was used for analysis. The result analysis and experiment show boss tower deformation very similar. Although the variation of CTQ has been decreased, cleanliness has been improved. Moreover, non-circular arm aperture is able to reduce swage effect.
An Efficient Vector System to Modify Cells Genetically (2011)

The transfer of foreign genes into mammalian cells has been essential for understanding the functions of genes and mechanisms of genetic diseases, for the production of coding proteins and for gene therapy applications. Currently, the identification and selection of cells that have received transferred genetic material can be accomplished by methods, including drug selection, reporter enzyme detection and GFP imaging. These methods may confer antibiotic resistance, or be disruptive, or require special equipment. In this study, we labeled genetically modified cells with a cell surface biotinylation tag by co-transfecting cells with BirA, a biotin ligase. The modified cells can be quickly isolated for downstream applications using a simple streptavidin bead method. This system can also be used to screen cells expressing two sets of genes from separate vectors.
Demonstration of error-free soliton transmission at 2.5 Gbit/s over more than 14,000 km (1991)

Error-free (bit error rate ≤ 10−10) soliton transmission at 2.5 Gbit/s over paths greater than 14,000 km, measured by a novel technique suitable for use in a recirculating loop, is reported.
Asphalt Study by Neuronal Networks. Correlation between Chemical and Rheological Properties (1997)

In this paper we investigate the prediction of rheological properties of bitumens using some structural parameters calculated from 13C NMR data. This study was carried out using methods of quantitative structure properties relationships (QSPR) and more particularly neural networks (NN). Such a mathematical tool can find out non linear relations between descriptors and properties. Two asphalt rheological properties, m (creep slope at low temperature) and G*/sin δ (stiffness at high temperature) were selected, whereas the descriptors are the average molecular parameters which characterize the hydrocarbon skeleton of bitumens. This work permitted to prove that the skeleton information contained in the average molecular parameters could be correlated to the m value but not to the G*/sin δ. Thus, the low-temperature rheological behavior appears to be highly dependent on the aliphatic part of the bitumens.
Gs alpha mediates epidermal growth factor-elicited stimulation of rat cardiac adenylate cyclase. (1990)

In an earlier study we demonstrated that epidermal growth factor (EGF) increases the cellular accumulation of cAMP in perfused rat hearts by stimulating the cardiac adenylate cyclase via a stimulatory GTP-binding protein (Nair, B. G., Rashed, H. M., and Patel, T. B. (1989) Biochem. J. 264, 563-571). Employing antiserum, CS1, generated against a synthetic decapeptide RMHLRQYELL representing the carboxyl terminus of Gs alpha, the involvement of Gs in mediating the effects of EGF on cardiac adenylate cyclase was further investigated. The CS1 antiserum specifically recognized two forms, (52 and 40 kDa) of Gs alpha in rat cardiac membranes; the 52 kDa being the predominant species. In functional assays of adenylate cyclase activity, the CS1 antiserum did not alter either aluminum fluoride- or forskolin-stimulated adenylate cyclase activity. Similarly, basal adenylate cyclase activity in the absence of guanyl-5'-yl imidodiphosphate (Gpp(NH)p) was also not altered by the CS1 antiserum. However, as compared with controls performed in the presence of non-immune serum, preincubation of cardiac membranes with the CS1 antiserum resulted in a concentration-dependent inhibition of Gpp(NH)p-, isoproterenol-, and EGF-stimulated activities. In experiments which monitored Gi function as the ability of different G(pp)NHp, (-)N6-(R-phenylisopropyl)adenosine and carbachol to inhibit forskolin-stimulated adenylate cyclase, CS1 antiserum by inhibiting Gs, increased the apparent activity of Gi. Overall, our data demonstrate that the CS1 antiserum can specifically inhibit Gs function and therefore the stimulation of adenylate cyclase by agonists whose actions are mediated by Gs. In this respect, the data presented here demonstrate that Gs is the G-protein involved in mediating EGF-elicited stimulation of cardiac adenylate cyclase. Additionally, the finding that CS1 antiserum can overcome the effects of Gpp(NH)p on Gs, but not Gi, suggests that the carboxyl-terminal region of Gs alpha is important in the interactions with GTP or its analogs.
Transcript length bias in RNA-seq data confounds systems biology (2009)

This article was reviewed by Rohan Williams (nominated by Gavin Huttley), Nicole Cloonan (nominated by Mark Ragan) and James Bullard (nominated by Sandrine Dudoit).
Experimental design optimization of the separation of the aromatic compounds in petroleum cuts by supercritical fluid chromatography (1993)

Abstract A experimental design optimization method is demonstrated for evaluation of the resolution of the performance mixture used in the proposed ASTM test to determine the aromatic content of aviation fuels. The method uses a Doehlert experimental matrix test to optimize the resolution and analysis time by varying the pressure and temperature of the supercritical carbon dioxide mobile phase. The separation between saturated and aromatic compounds was optimized using only seven experiments. With this procedure, the analysis time required for determination of the total aromatic content of more complex samples can be reduced to less than 10 min.
Numerical and Physical Issues in Large Eddy Simulation of Turbulent Flows. (1998)

The recent work on large eddy simulation(LES)of turbulent flows at the Center for Turbulence Research is reviewed. This includes progress on issues surrounding the governing equations and filtering, subgrid scale and wall layer modeling, and spatial discretization. Recent results from LES of separated flows, and two promising applications of LES to flows encountered in combustors are presented.
Energy Efficient Control Strategy for Machine Tools with Stochastic Arrivals and Time Dependent Warm-up (2014)

Energy efficiency in manufacturing is becoming a challenging goal due to the demand of this sector in the worldwide scenario. One of the measures for saving energy is the implementation of control strategies that reduce machine energy consumption during the machine idle periods. This paper extends a threshold policy, that switches off the machine during interruptions of part flow, by modelling explicitly the warm-up time as dependent on the time period the machine stays in low power consumption state. The optimal policy parameter is provided numerically for general distributions of the part arrival time and general functions modelling the warm-up time. Numerical results are based on data acquired with dedicated experimental measurements on a real machining center.
La estrategia de internacionalización de Aceites del Sur (2004)

El sector de aceite de oliva en Espana se caracteriza por estar muy atomizado y por ser muy competitivo. Despues de cosechar exitos en el mercado nacional, la empresa Aceites del Sur decide en 1989 lanzarse a la aventura de exportar su marca apoyado por las bondades que se cuentan de un producto tipicamente espanol. El resultado fu muy distinto. Su experiencia en America no fue nada positiva, sin embargo consiguen hacerse un hueco en mercados tan complicados como Asia o Rusia. En este articulo se explica como se realizo todo ese proceso de internacionalizacion y que resultados se obtuvieron en los distintos mercados.
The role of cytochrome P4502D6 in the metabolism of paroxetine by human liver microsomes. (1992)

Paroxetine is a selective serotonin reuptake inhibitor possessing anti-depressant activity. Demethylenation of the methylenedioxy phenyl group is the initial step in its metabolism, the liberated carbon appearing in vitro as formate. A radioassay involving [14C-methylenedioxy] paroxetine was developed and used to examine the role of cytochrome P4502D6 in paroxetine metabolism by human liver microsomes. The rate of formate production was much higher in microsomes from an extensive metaboliser of debrisoquine than from a poor metaboliser. Also, demethylenation of paroxetine was inhibited by the quinidine and quinine isomer pair in microsomes from the extensive metaboliser only. These observations strongly suggested that the process was catalysed by the enzyme cytochrome P4502D6. Metabolism could not be completely inhibited by quinidine, the residual activity representing the contribution of at least one other enzyme. The ability of microsomes from a poor metaboliser of debrisoquine to demethylenate paroxetine provided further evidence for the involvement of an enzyme distinct from P4502D6. This was confirmed by kinetic analysis of the process in microsomes from both poor and extensive metabolisers. It is concluded that, in man, the initial step of paroxetine metabolism is performed by at least two enzymes, one of which is cytochrome P4502D6.
[Imaging subcutaneous atrophy in circumscribed scleroderma with 20 MHz B-scan ultrasound]. (1993)

The technique of 20-MHz B-scan sonography is non-invasive and allows quantification of the different compartments of the skin. Seven patients with atrophic linear circumscribed scleroderma and one patient with guttate circumscribed scleroderma were examined by ultrasound. All patients were found to have a total or subtotal loss of subcutaneous fatty tissue, whereas the thickness of the dermis remained almost unchanged. These findings should lead to further investigation of the pathophysiological mechanism involved in subcutaneous atrophy in circumscribed scleroderma.
Crown cation complex effects. 20. Syntheses and cation binding properties of carbon-pivot lariat ethers (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrown cation complex effects. 20. Syntheses and cation binding properties of carbon-pivot lariat ethersDennis M. Dishong, Craig J. Diamond, Michael I. Cinoman, and George W. GokelCite this: J. Am. Chem. Soc. 1983, 105, 3, 586–593Publication Date (Print):February 1, 1983Publication History Published online1 May 2002Published inissue 1 February 1983https://pubs.acs.org/doi/10.1021/ja00341a045https://doi.org/10.1021/ja00341a045research-articleACS PublicationsRequest reuse permissionsArticle Views1715Altmetric-Citations114LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A cloned cyanobacterial gene for glutamine synthetase functions in Escherichia coli, but the enzyme is not adenylylated. (1981)

The coding sequence for Anabaena 7120 glutamine synthetase [L-glutamate:ammonia ligase (ADP-forming), EC 6.3.1.1] are shown to be contained within a 7.5-kilobase-pair (kbp) HindIII fragment that has been cloned by plaque hybridization. The hybridization probe for the cyanobacterial gene was a recombinant plasmid containing the glnA gene from Escherichia coli K-12. Evidence that the cloned Anabaena fragment contains the glnA gene includes complementation of a glnA deletion mutant of E. coli and immunological identity of the enzyme produced by the cloned Anabaena fragment in E. coli with glutamine synthetase purified from Anabaena 7120. Heteroduplex analysis reveals 0.65 kbp of homology between the 7.5-kbp Anabaena 7120 fragment and an 11-kbp E. coli fragment that codes for E. coli glutamine synthetase. Studies of Anabaena glnA gene activity in E. coli suggest that the cyanobacterial gene is not repressible and that the Anabaena 7120 glutamine synthetase is not adenylylated in E. coli.
Hollow Carved Single-Crystal Mesoporous Silica Templated by Mesomorphous Polyelectrolyte−Surfactant Complexes (2010)

Hierarchically nanoporous single-crystal mesoporous silica was fabricated by using mesomorphous polyelectrolyte−surfactant complexes as dynamic template. During the kinetic self-assembly, the order of the mesomorphous complexes was realigned and evolved into Pm3̅n mesostructured silica, and the phase-separated polymer served as the template for secondary nanopores within the single crystal SBA-1.
<i>Arabidopsis</i> PYR/PYL/RCAR Receptors Play a Major Role in Quantitative Regulation of Stomatal Aperture and Transcriptional Response to Abscisic Acid (2012)

Abscisic acid (ABA) is a key hormone for plant growth, development, and stress adaptation. Perception of ABA through four types of receptors has been reported. We show here that impairment of ABA perception through the PYRABACTIN RESISTANCE1 (PYR1)/PYR1-LIKE (PYL)/REGULATORY COMPONENTS OF ABA RECEPTORS (RCAR) branch reduces vegetative growth and seed production and leads to a severe open stomata and ABA-insensitive phenotype, even though other branches for ABA perception remain functional. An Arabidopsis thaliana sextuple mutant impaired in six PYR/PYL receptors, namely PYR1, PYL1, PYL2, PYL4, PYL5, and PYL8, was able to germinate and grow even on 100 μM ABA. Whole-rosette stomatal conductance (Gst) measurements revealed that leaf transpiration in the sextuple pyr/pyl mutant was higher than in the ABA-deficient aba3-1 or ABA-insensitive snrk2.6 mutants. The gradually increasing Gst values of plants lacking three, four, five, and six PYR/PYLs indicate quantitative regulation of stomatal aperture by this family of receptors. The sextuple mutant lacked ABA-mediated activation of SnRK2s, and ABA-responsive gene expression was dramatically impaired as was reported in snrk2.2/2.3/2.6. In summary, these results show that ABA perception by PYR/PYLs plays a major role in regulation of seed germination and establishment, basal ABA signaling required for vegetative and reproductive growth, stomatal aperture, and transcriptional response to the hormone.
Effects of linear and nonlinear piezoelectricity on the electronic properties of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi mathvariant="normal">In</mml:mi><mml:mi mathvariant="normal">As</mml:mi><mml:mo>∕</mml:mo><mml:mi mathvariant="normal">Ga</mml:mi><mml:mi mathvariant="normal">As</mml:mi></mml:mrow></mml:math>quantum dots (2006)

The existence of enormous strain fields in self-assembled quantum dots has led to the expectation of dramatic effects of piezoelectricity. However, only linear piezoelectric tensors were used in all previous calculations. We calculate the piezoelectric properties of self-assembled quantum dots using the linear and quadratic piezoelectric tensors derived from first-principles density functional theory. We find that the previously ignored quadratic term has similar magnitude as the linear term and the two terms tend to cancel each other. We show the effect of piezoelectricity on electron and hole energy levels and wave functions as well as on correlated absorption spectra.
TGF-beta 1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis (1997)

Our previous studies demonstrated that TGF-beta 1 is required for efficient in vitro generation of dendritic cells (DC) from CD34+ progenitor cells under serum-free conditions. Here we show that TGF-beta 1 promotes the growth and differentiation of DC primarily by protecting the viability of DC precursors and not by enhancing their proliferative response. Addition of TGF-beta 1 to TNF-alpha, granulocyte-macrophage CSF, and stem cell factor-supplemented cultures had no significant effect on the proportions of cycling cells. Already at 72 h of culture, however, the proportion of apoptotic cells was reduced by more than 60% in the presence of TGF-beta 1. This early protective effect of TGF-beta 1 correlates with the outgrowth of higher numbers and proportions of CD1a+ DC at day 7 of culture. It also correlates with a significantly reduced Fas/APO-1 expression on TGF-beta 1 cultured cells. In contrast, granulomonocytic cells, also arising under these culture conditions, are not affected to such an extent. They are found at equal proportions, both in the presence and absence of TGF-beta 1. The striking DC growth-promoting effect of TGF-beta 1 could only be observed when both TGF-beta 1 and TNF-alpha were present in the cultures. TGF-beta 1, in the absence of TNF-alpha, rather inhibited than enhanced cell expansion. Thus, for optimal in vitro DC development to occur, all four cytokines must obviously act in concert and the combination of TGF-beta 1 with TNF-alpha seems to be particularly critical.
Integrated Planar Microlens And Its Applications (1988)

The paper describes a monolithically integrated planar microlens array and its applications. An ion exchange technology is applied to realize the microlens array with diameters of 10 - 1000 pm and N.A. of 0.25. Applications to optical fiber communications, combinations with CCD arrays and optical computing are demonstrated.
Instability of anhydrous tetra-n-alkylammonium fluorides (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInstability of anhydrous tetra-n-alkylammonium fluoridesRamesh K. Sharma and James L. FryCite this: J. Org. Chem. 1983, 48, 12, 2112–2114Publication Date (Print):June 1, 1983Publication History Published online1 May 2002Published inissue 1 June 1983https://pubs.acs.org/doi/10.1021/jo00160a041https://doi.org/10.1021/jo00160a041research-articleACS PublicationsRequest reuse permissionsArticle Views3240Altmetric-Citations231LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
BETTER: handling best effort traffic in the ATM networks (2002)

This paper addresses the problem of handling best effort traffic (BET) in ATM networks. This type of traffic usually consists of information cell transfer without any guarantees about the quality of service. We show that its transfer characteristics strictly depend on the cell scheduling mechanisms used in the ATM switches. The comparative studies take into account the following queue disciplines: FIFO without priorities, FIFO within predefined priorities, weighted fair queuing algorithm and control by the cycle. The ATM services that handle BET traffic are ABR and UBR. A new way of handling BET traffic "best effort traffic takes empty round" (BETTER) controlled by a cycle mechanism is proposed. The outcome of the numerical study shows that BETTER has some advantages over other queuing mechanisms.
STANDARD METHOD FOR THE 1-INCH DYNAMIC TEAR TEST (1969)

The report describes a standard method for conducting dynamic tear (DT) tests to determine the DT energy (fracture toughness) value for structural base metal and weld metal using the standard 1-in. DT test specimen. A description of the apparatus, the dimensions and preparation of specimens, and details of the testing procedures are given. Use of this standard method is recommended for specification purposes, and it provides for comparison of results between different laboratories on a common basis.
Line Drawings from 3D Models (2019)

This tutorial describes the geometry and algorithms for generating line drawings from 3D models, focusing on occluding contours. The geometry of occluding contours on meshes and on smooth surfaces is described in detail, together with algorithms for extracting contours, computing their visibility, and creating stylized renderings and animations. Exact methods and hardware-accelerated fast methods are both described, and the trade-offs between different methods are discussed. The tutorial brings together and organizes material that, at present, is scattered throughout the literature. It also includes some novel explanations, and implementation tips. A thorough survey of the field of non-photorealistic 3D rendering is also included, covering other kinds of line drawings and artistic shading.
A Review of Ammonia-Based Thermochemical Energy Storage for Concentrating Solar Power (2011)

The development of a thermochemical energy storage system based on ammonia, for use with concentrating solar power is discussed in this paper. This is one of a number of storage options for concentrating solar power, including molten-salt storage, which is already operating commercially. The ammonia storage development has involved prototype solar receiver/reactors operated in conjunction with a 20-m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> dish concentrator, as well as closed-loop storage demonstrations. An ongoing computational study deals with the performance of an ammonia receiver for a 489-m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> dish concentrator. The ammonia storage system could employ industry-standard ammonia synthesis converters for superheated steam production. A standard 1500 t/day ammonia synthesis reactor would suffice for a 10-MW <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">e</sub> baseload plant with 330 large 489-m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> dishes. At this stage, an updated economic assessment of the system would be valuable.