gebhart/patrepeval huggingface dataset:
Amphiphilic Polyethylenes Leading to Surfactant-Free Thermoresponsive Nanoparticles (2010)

Linear copolymers of ethylene and acrylic acid (PEAA) were prepared by catalytic polymerization of ethylene and tert-butyl acrylate followed by hydrolysis of the ester groups. The copolymers contained COOH groups inserted into the crystalline unit cell with formation of intramolecular hydrogen-bonds, as established on the basis of differential scanning calorimetry (DSC), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) studies. A solvent-exchange protocol, with no added surfactant, converted a solution in tetrahydrofuran of a PEAA sample containing 12 mol % of acrylic acid (AA) into a colloidally stable aqueous suspension of nanoparticles. Transmission electron microscopy (TEM), dynamic light scattering (DLS), and high sensitivity differential scanning calorimetry (HS-DSC) were used to characterize the nanoparticles. They are single crystals of elongated shape with a polar radius of 49 nm (σ = 15 nm) and an equatorial radius of 9 nm (σ = 3 nm) stabilized in aqueous media via carboxylate groups located preferentially on the particle/water interface. The PEAA (AA: 12 mol %) nanoparticles dispersed in aqueous media exhibited a remarkable reversible thermoresponsive behavior upon heating/cooling from 25 to 80 °C.
III--Combined Reliability and Economy in Operation of Large Electric Systems (1932)

This paper discusses the practises in use on the Philadelphia Electric Company system in attaining the maximum system economy consistent with high degree of service reliability. The system comprises not only steam electric stations of different efficiencies, but also a large hydroelectric plant and a major high-voltage interconnection with two large neighboring utilities, so that problems of operating economy are both highly important and complex in character. The paper also directs attention to problems of investment economy with a view toward securing the best balance of fixed charges, operating costs, and service reliability.
Simultaneous Pipelining in QPipe: Exploiting Work Sharing Opportunities Across Queries (2006)

Data warehousing and scientific database applications operate on massive datasets and are characterized by complex queries accessing large portions of the database. Concurrent queries often exhibit high data and computation overlap, e.g., they access the same relations on disk, compute similar aggregates, or share intermediate results. Unfortunately, run-time sharing in modern database engines is limited by the paradigm of invoking an independent set of operator instances per query, potentially missing sharing opportunities if the buffer pool evicts data early.
The Diagnosis and Management of Congenital Hemophilia (2012)

Hemophilia is the most common, severe, inherited bleeding disorder recognized in humans and makes up the largest proportion of patients followed in most bleeding disorders' clinics. Persons with hemophilia have a life-long bleeding tendency that roughly correlates to their endogenous coagulant factor VIII (FVIII) or factor IX (FIX) level (FVIII:C and FIX:C). The hallmark of bleeding in severe hemophilia is musculoskeletal bleeds (soft tissue, muscle and joint bleeds) but persons with hemophilia are also prone to other bleeds including intracranial bleeds. The neonatal period is a particularly vulnerable period for persons with severe hemophilia. Diagnosing hemophilia is mainly based on measuring FVIII:C and FIX:C levels and on distinguishing hemophilia from other conditions that can cause a low FVIII:C or FIX:C level. Management involves preventing bleeds and rapidly treating those that occur. Bleed prevention in severe hemophilia can be accomplished by avoiding high-risk activities, taking appropriate precautions and early commencement of life-long prophylaxis. With proper management, persons with severe hemophilia can now live an essentially normal life. The development of an inhibitor does however complicate management. This review will summarize the very complex and multifaceted aspects of diagnosing and managing persons with hemophilia.
Variation in the Use of Cardiac Procedures after Acute Myocardial Infarction (1995)

Physicians in Texas were more likely to perform angiography than physicians in New York for patients whose conditions allowed more discretion in the use of cardiac procedures. On average, there appears to be no advantage with respect to mortality or health-related quality of life to performing the procedures at the higher rate used in Texas.
Remitting Seronegative Symmetrical Synovitis with Pitting Edema (1995)

We describe four patients who presented with seronegative inflammatory peripheral polyarthritis with pitting edema. All of these patients had spontaneous resolution of their disease over 9-18 months. None of them developed erosions or relapse after prolonged follow-up. Recognition of the features described may allow for conservative therapy with less toxic drugs.
Emotional Behavior Decision Model Based on Linear Dynamic Systems for Intelligent Service Robots (2007)

This paper introduces an emotional behavior decision model for intelligent service robots. An emotional model should make different behavior decisions according to the purpose of the robots. We propose an emotional behavior decision model which can change the character of emotional model and make different behavior decisions although the situation and environment remain the same. We defined each emotional element such as reactive dynamics, internal dynamics, emotional dynamics, and behavior dynamics by state dynamic equations. The proposed system model is a linear system. If you want to add one external stimulus or behavior, you need to add just one dimensional vector to the matrix of external stimulus or behavior dynamics. The case of removing is same. The change of reactive dynamics, internal dynamics, emotional dynamics, and behavior dynamics also follows the same procedure. We implemented the proposed emotional behavior decision model and verified its performance.
Visible multi-quantum-well laser diode composed of (AlGaAs) <sub>m</sub> (GaAs) <sub>n</sub> short period superlattice (1989)

Short-period (AlGaAs)m(GaAs)n superlattices have been applied to the active layer in a GRIN-SCH multi-quantumwell laser diode using molecular beam epitaxy. A short wavelength of 720 nm and high-temperature CW operation at over 100°C were achieved with a low threshold current of 24 mA and high differential quantum efficiency of 75% at room temperature.
Multisensorsystem mit schmalbandigen Radarsensoren zum Fahrzeugseitenschutz (2014)

Die Arbeit liefert einen Beitrag für einen verbesserten Fahrzeugseitenschutz mit fusionierten Radarsensordaten, zur sensorunabhängigen 360-Grad-Kollisionserkennung und zur genaueren Beschreibung des Sensormodells, insbesondere unter Beachtung der Auflagen der zukünftigen Frequenzregulierung im 24-GHz-Frequenzband.
3D Reconstruction of 138 KV Power-lines from Airborne LiDAR Data (2014)

Due to infrequent and imprecise maintenance inspection in power-line corridors, accidents can be caused by interferences, for instance, surrounding trees. Transmission power-line inspection conventionally relies on the participation of ground personnel and airborne camera to patrol power-lines, and is limited by intensive labour, and difficult working conditions and management. Airborne light detection and ranging (LiDAR) has proven a powerful tool to overcome these limitations to enable more efficient inspection. Active airborne LiDAR systems directly capture the 3D information of power infrastructure and surrounding objects. This study aims at building a semi-automatic 3D reconstruction workflow for power-lines extracted from airborne LiDAR data of 138 kV transmission line corridors (500 m by 340 m) in Nanaimo, BC, Canada. \nThe proposed workflow consists of three components: detection, extraction, and fitting. The power-lines are automatically detected with regular geometric shape using a set of algorithms, including density-based filtering, Hough transform and concatenating algorithm. The complete power-lines are then extracted using a rectangular searching technique. Finally, the 3D power-lines are reconstructed through fitting by a hyperbolic cosine function and least-squares fitting. A case study is carried out to evaluate the proposed workflow for hazard tree detection in the corridor. \nThe results obtained demonstrate that power-lines can be reconstructed in 3D, which are useful in detection of hazard trees to support power-line corridor management.
Propagation of picosecond electrical pulses on a silicon-based microstrip line with buried cobalt silicide ground plane (1991)

A microstrip line with a highly conducting cobalt silicide (CoSi2) ground plane buried 7 μm below the surface of a single-crystal silicon wafer is presented. This new transmission line shows significantly reduced dispersion up to 100 GHz bandwidth compared to a conventional microstrip line with the ground plane on the back of the substrate, while being able to support active devices in the silicon dielectric. After propagating 5 mm, the rise time (10%–90%) of an electrical pulse increases only from 2.5 to 3.7 ps as opposed to an increase from 2.7 to 11.3 ps on a conventional microstrip line.
Pulmonary Artery Denervation for Treatment of a Patient with Pulmonary Hypertension Secondary to Left Heart Disease (2016)

Pulmonary hypertension (PH) predicts poor outcome in patients with left heart disease. A 62‐year‐old man was referred for heart failure associated with ischemic cardiomyopathy. He received a diagnosis of combined postcapillary and precapillary PH secondary to left heart disease on the basis of hemodynamic parameters. After the pulmonary artery denervation procedure was performed, hemodynamic parameters were markedly improved, which resulted in a significant increase in functional capacity.
Design of Fracture Fixation Plate for Necessary and Sufficient Bone Stress Shielding (2004)

The objective of treating the fractured bone is to achieve painless functioning of the bone and undisturbed healing at the fracture. Internal fixation by stiff bone-plate is one of the standard methods to achieve these objectives. Recently, there is considerable interest in the usage of compliant plates to enhance bone healing with reduced stress shielding. Herein, first an analytical solution is developed to determine screw forces in the bone-plate assembly that conforms the plate and the bone under bending load. Based on the analytical calculations, an optimal fixator plate selection criterion for necessary and sufficient stress shielding is proposed. Second, effectiveness of employing a non-homogeneous stiffness graded (SG) plate rather than a homogeneous stainless steel (SS) plate for stress shielding is investigated using a finite element method. It is found that stress shielding on bone by SG plate is less compared to SS plate.
Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation. (1997)

Chronic wound healing states are often associated with aging, and despite the increased number of aged patients with nonhealing wounds, controversy still exists concerning the effects of age on wound repair. Our previous work showed that in both venous ulcers in humans and acute wounds in aged animals, fibronectin, an early component in granulation tissue, is deficient compared to normal skin and acute wounds in healthy young animals, respectively. In the present study, we have determined the protease responsible for fibronectin degradation by analyzing tissue taken from the margins of chronic venous ulcers and standardized acute cutaneous wounds collected from a large cohort of "Health status"-defined aged human subjects (screened as per the SENIEUR protocol). When tissue samples were subjected to fibronectin zymography, the main protease involved in the breakdown of fibronectin in both venous ulcers and acute wounds of elderly subjects was found to be a serine protease with a molecular weight of approximately 30 kd. This protease was identified as neutrophil elastase by immunoblotting. In tissue biopsies, elastase was localized to granulocytes by immunocytochemical techniques and shown to be present in greater quantities in venous ulcers and Day-7 and -14 healing acute wounds of healthy aged subjects relative to those of young subjects. The highest quantities were found in acute wounds of elderly women. Our results suggest that the process of aging in healthy human subjects is associated with an up-regulation of elastase during acute wound healing and that an abnormality in down-regulation of this protease could be partially responsible for the transition to chronic wound healing states in the aged.
Scalable molecular dynamics on CPU and GPU architectures with NAMD (2020)

NAMDis a molecular dynamics program designed for high-performance simulations of very large biological objects on CPU- and GPU-based architectures. NAMD offers scalable performance on petascale parallel supercomputers consisting of hundreds of thousands of cores, as well as on inexpensive commodity clusters commonly found in academic environments. It is written in C++ and leans on Charm++ parallel objects for optimal performance on low-latency architectures. NAMD is a versatile, multipurpose code that gathers state-of-the-art algorithms to carry out simulations in apt thermodynamic ensembles, using the widely popular CHARMM, AMBER, OPLS, and GROMOS biomolecular force fields. Here, we review the main features of NAMD that allow both equilibrium and enhanced-sampling molecular dynamics simulations with numerical efficiency. We describe the underlying concepts utilized by NAMD and their implementation, most notably for handling long-range electrostatics; controlling the temperature, pressure, and pH; applying external potentials on tailored grids; leveraging massively parallel resources in multiple-copy simulations; and hybrid quantum-mechanical/molecular-mechanical descriptions. We detail the variety of options offered by NAMD for enhanced-sampling simulations aimed at determining free-energy differences of either alchemical or geometrical transformations and outline their applicability to specific problems. Last, we discuss the roadmap for the development of NAMD and our current efforts toward achieving optimal performance on GPU-based architectures, for pushing back the limitations that have prevented biologically realistic billion-atom objects to be fruitfully simulated, and for making large-scale simulations less expensive and easier to set up, run, and analyze. NAMD is distributed free of charge with its source code at www.ks.uiuc.edu.
LEGISLATIVE POLICIES AND CULTURE ON PARENTING PRACTICES: improving the parent-child relationship in South Africa (2019)

Os relacionamentos pai-filho são frequentemente descritos como vínculos únicos e duradouros que ocorrem entre um cuidador / pai e seu filho. Vários documentos de políticas legislativas sul-africanas foram implementados para orientar a prestação de serviços às famílias e fortalecer o relacionamento entre pais e filhos nas famílias. Este artigo visa examinar criticamente os quadros atuais e explorar o que é necessário na África do Sul, a fim de melhorar o relacionamento entre pais e filhos e os resultados gerais do desenvolvimento infantil. Utilizando uma perspectiva ecológica, os aspectos identificados como benéficos para melhorar o relacionamento entre pais e filhos na África do Sul são discutidos em nível micro, meso e macro. As influências culturais são consideradas e são fornecidas recomendações para melhorar o relacionamento entre pais e filhos em um contexto sul-africano.Palavras-chave: Relacionamento pai-filho. Desenvolvimento infantil. Desenvolvimento na primeira infância. Estilos parentais. Cultura. Teoria dos sistemas ecológicos.
Phenylalkylamines with potential psychotherapeutic utility. 2. Nuclear substituted 2-amino-1-phenylbutanes (1980)

A series of 2-amino-1-(4-substituted-2,5-dimethoxyphenyl)butanes (Table V) was prepared as analogues of (R)-2-amino-1-(2,5-dimethoxy-4-methylphenyl)butane (1a). 1-(2,5-Dimethoxyphenyl)-2-(N-phthalimido)butane (7) was utilized as a synthetic intermediate common to many of the target compounds. Animal data are presented indicating that most of these analogues have low hallucinogenic potential. Selected compounds were compared with 1a in an avoidance-response acquisition model which differentiates between 1a and the human hallucinogens DOM (2a) and DOET (2b). Structure-activity relationships of these analogues are discussed.
The Crosstalk between the Gut Microbiota and Mitochondria during Exercise (2017)

Many physiological changes occur in response to endurance exercise in order to adapt to the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species (ROS) production and acute inflammatory responses. Mitochondria are organelles within each cell that are crucial for ATP production and are also a major producer of ROS and reactive nitrogen species during intense exercise. Recent evidence shows there is a bidirectional interaction between mitochondria and microbiota. The gut microbiota have been shown to regulate key transcriptional co-activators, transcription factors and enzymes involved in mitochondrial biogenesis such as <i>PGC-1</i>α<i>, SIRT1</i>, and <i>AMPK</i> genes. Furthermore, the gut microbiota and its metabolites, such as short chain fatty acids and secondary bile acids, also contribute to host energy production, ROS modulation and inflammation in the gut by attenuating TNFα- mediated immune responses and inflammasomes such as <i>NLRP3</i>. On the other hand, mitochondria, particularly mitochondrial ROS production, have a crucial role in regulating the gut microbiota via modulating intestinal barrier function and mucosal immune responses. Recently, it has also been shown that genetic variants within the mitochondrial genome, could affect mitochondrial function and therefore the intestinal microbiota composition and activity. Diet is also known to dramatically modulate the composition of the gut microbiota. Therefore, studies targeting the gut microbiota can be useful for managing mitochondrial related ROS production, pro-inflammatory signals and metabolic limits in endurance athletes.
Effect of Sipjeondaebo-Tang on Cancer-Induced Anorexia and Cachexia in CT-26 Tumor-Bearing Mice (2014)

Cancer-associated anorexia and cachexia are a multifactorial condition described by a loss of body weight and muscle with anorexia, asthenia, and anemia. Moreover, they correlate with a high mortality rate, poor response to chemotherapy, poor performance status, and poor quality of life. Cancer cachexia is regulated by proinflammatory cytokines such as interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and tumor necrosis factor- α (TNF- α). In addition, glucagon like peptide-1 (GIP-1), peptide YY (PYY), ghrelin, and leptin plays a crucial role in food intake. In this study, we investigated the therapeutic effects of one of the traditional herbal medicines, Sipjeondaebo-tang (Juzen-taiho-to in Japanese; SJDBT), on cancer anorexia and cachexia in a fundamental mouse cancer anorexia/cachexia model, CT-26 tumor-bearing mice. SJDBT was more significantly effective in a treatment model where it was treated after anorexia and cachexia than in a prevention model where it was treated before anorexia and cachexia on the basis of parameters such as weights of muscles and whole body and food intakes. Moreover, SJDBT inhibited a production of IL-6, MCP-1, PYY, and GLP-1 and ameliorated cancer-induced anemia. Therefore, our in vivo studies provide evidence on the role of SJDBT in cancer-associated anorexia and cachexia, thereby suggesting that SJDBT may be useful for treating cancer-associated anorexia and cachexia.
An Approach to Urban Traffic State Estimation by Fusing Multisource Information (2009)

This paper presents an information-fusion-based approach to the estimation of urban traffic states. The approach can fuse online data from underground loop detectors and global positioning system (GPS)-equipped probe vehicles to more accurately and completely obtain traffic state estimation than using either of them alone. In this approach, three parts of the algorithms are developed for fusion computing and the data processing of loop detectors and GPS probe vehicles. First, a fusion algorithm, which integrates the federated Kalman filter and evidence theory (ET), is proposed to prepare a robust, credible, and extensible fusion platform for the fusion of multisensor data. After that, a novel algorithm based on the traffic wave theory is employed to estimate the link mean speed using single-loop detectors buried at the end of links. With the GPS data, a series of technologies are combined with the geographic information systems for transportation (GIS-T) map to compute another link mean speed. These two speeds are taken as the inputs of the proposed fusion platform. Finally, tests on the accuracy, conflict resistance, robustness, and operation speed by real-world traffic data illustrate that the proposed approach can well be used in urban traffic applications on a large scale.
Polarisation optical time domain reflectometry (1980)

A proposed new optical fibre technique will allow measurement of the spatial distribution of physical fields, and will also allow location of anomalous features in single polarisation state monomode optical fibres such as are under discussion for very high bandwidth communication.
The Role of Sensory Cues and Feeding Context in the Mediation of Pine-Needle Oil's Repellency in Prairie Voles (1995)

Pine-needle oil inhibits feeding in vertebrate species through sensory cues. Prairie voles (Microtus ochrogaster) significantly decreased their ingestion of raw apple pieces when pineneedle oil (10% vol/vol) was applied as a repellent coating. During single-choice tests, voles selected similar amounts of sunflower seeds from pine-needle oil-scented jars and vegetable oil-treated jars. However, when jars containing both stimuli were presented simultaneously, voles retrieved significantly more food from the vegetable oil-treated jars than the pine-needle oil-treated jars. Neonatal administration of capsaicin chronically depletes neurotransmitters in C- and A-a fibers greatly diminishing or abolishing pain transmission in the affected neurons (i.e., trigeminal nerve). Capsaicin-desensitized prairie voles decreased their ingestion of pine-needle oil-treated apples to the same extent as the sham-injected control group of animals, suggesting that pineneedle oil's repellency was not mediated by activation of pain fibers. In settings where alternative foods are available, and where minimal sampling of the product does not represent a hazard, Siberian pine-needle oil may be useful as a rodent repellent.