gebhart/patrepeval huggingface dataset:
Controlled trial of effect of documented cardiovascular risk scores on prescribing (2003)

One in 200 babies in the Republic of Ireland is stillborn. Investigating the cause of stillbirth helps gives the clinician valuable information in relation to managing a subsequent pregnancy. A PM is the most useful and informative investigation that can be performed in the postnatal period. PM uptake rates in Ireland are low, circa 50%. There are few guidelines for staff on how to broach this issue and it is possible that individual clinicians’ attitudes to PM affect the uptake rates. We conducted a questionnaire study examining the attitudes of midwives and obstetricians in Ireland to perinatal PM. This questionnaire has been validated by the ISA, ANZSA and also by UK−Sands. In total 117 questionnaires were completed. Obstetricians made up 44% of respondents - the rest were midwives. 17% of respondents never gave information to parents about PMs. Of those who did, only 37% did so at the time of diagnosis. The majority of respondents (76%) were dissatisfied with the quality of training received in how to counsel for PM. 46% of respondents were satisfied with the quality of information materials available in counselling parents re PM. 83% felt that a clinical guideline would be helpful to assist parents in decision making. To summarise, there is a wide variation among health care staff in the current knowledge and clinical practise relating to stillbirth and consenting for PM. We anticipate that by introducing a standardised guideline and improving staff education that our PM rates will improve dramatically.
Infectivity of Immature Neurons to Zika Virus: A Link to Congenital Zika Syndrome (2016)

These findings strengthen the reported association between high incidences of microcephaly and ZIKV infection in newborns in Brazil. Our results suggest that the undifferentiated neurons are highly permissive to ZIKV infection, as one would expect during the early stages of neurogenesis in fetal brains; whereas differentiated neurons, representative of adult brain neurons, are relatively resistant to the virus, which explains the rare occurrence of neurological complications in adults infected with ZIKV. Our studies confirm the neurotropism of the ZIKV strain closely related to the current epidemic in Latin America.
Load balancing and query optimization in dataflow parallel evaluation of Datalog programs (2002)

A dataflow model to obtain parallelism in the evaluation of Datalog is presented. This model performs query evaluation as a dataflow through a network of communicating concurrent processes capable of solving the query. This process network is based on the intensional database definition, plus the concrete query to be evaluated. A cost model to cope with the load balancing problem is described. A load balancing algorithm is presented and discussed. An algorithm to optimize the evaluation is described which is based on process network rewriting. This utilizes information in the query bindings to be evaluated in order to optimize the dataflow graph.
Electrospun PCL membranes incorporated with biosynthesized silver nanoparticles as antibacterial wound dressings (2015)

An open wound is highly prone to bacterial colonization and infection. Bacterial barrier property is an important factor that determines the success of a wound coverage material. Apart from the bacterial barrier property, presence of antibacterial agents can successfully eliminate the invasion and colonization of pathogen in the wound. Silver nanoparticles are well-known antimicrobial agents against a wide range of microorganisms. Biosynthesized silver nanoparticles are more acceptable for medical applications due to superior biocompatibility than chemically synthesized ones. Presence of biomolecules on biosynthesized silver nanoparticles enhances its therapeutic efficiency. Polycaprolactone (PCL) is a well-known material for biomedical applications including wound dressings. Electrospinning is an excellent technique for the fabrication of thin membranes for wound coverage applications with barrier property against microbes. In this paper, we report the fabrication and characterization of electrospun PCL membranes incorporated with biosynthesized silver nanoparticles for wound dressing applications.
Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis (2016)

The National Institute for Health Research Health Technology Assessment programme.
Preparation of Crown Ethers with Isoxazolyl-Lariats: Homologation of Isoxazole Aldehydes, and a Critical Comparison of Lariat Functional Moieties for Lanthanide Extraction (1991)

A critical comparison of several lariat ether functional moieties is presented.The synthesis of two isoxnzolyl-lariat ethers is described.The lariat ether (2, n=l) undergoes B-fragmentation on electron transfer reductive ringopening with samarium diiodide.The isoxazole moiety was then homologated to overcome this problem, and isoxazole lariat ether (2, n=3) was obtained.The isoxazole (2, n=3) and !%diketone (3, n=3) crowns were evaluated in lanthanide shift studies and liquid-liquid extraction studies.Finally, lateral metalation and elecrrophilic quenching with carbon dioxide produced the carboxylic acid (12) which proved to be an efficient ligmd for the liquid-liquid extraction of lanthanides.Lxriat ethers are molecules which contain a crown ether macrocycle in combination with a pendant lariat capable of complexing a guest mo~ecule.~It has been previously reported by Wai2 that dibenzo-16-crown-5-6-oxyacetic acid is an effective host for extraction of f-block element ion guests into organic solvent.A serics of extraction controls, as well as ir and 1~ nmr studies of the lanthanum complexes of these lariat ethers, led Wai and co-workers to the conclusion that both lariat and cavity were necessary for extraction success.The report by the groups of Bartsch and Lipscomb, of the structure of the lithium complex of dibenzo-14-crown-4-oxyacetic acid, indicates that the tether n=l is not sufficiently long for the metal ion to reach both 1ari;u and macrocyclic cavity, and in fact, a water molecule was found in between the lithium ion and the carboxylate group in the crystal structure.3Examination of molecular models and computer-aided modeling suggested that for the dibenzo-16-crown-5-6-oxyacetic acid complex with lanthanum, when the carboxylate is bound to the lanthanide ion, the "bottom" of the macrocyclic cavity could not be directly involved with complexation.We concluded that in terms of optimizing extraction efficiency andlor selectivity, it would be useful to compare crown ethers containing lariats capable of bringing both cavity and lariat to bear on binding the metal ion.In connection with our interest in the chemistry of isoxazo~es,~
Invariant Sema5A inhibition serves an ensheathing function during optic nerve development (2003)

Retinal axon pathfinding from the retina into the optic nerve involves the growth promoting axon guidance molecules L1, laminin and netrin 1, each of which governs axon behavior at specific regions along the retinal pathway. In identifying additional molecules regulating this process during embryonic mouse development, we found that transmembrane Semaphorin5A mRNA and protein was specifically expressed in neuroepithelial cells surrounding retinal axons at the optic disc and along the optic nerve. Given that growth cone responses to a specific guidance molecule can be altered by co-exposure to a second guidance cue, we examined whether retinal axon responses to Sema5A were modulated by other guidance signals axons encountered along the retinal pathway. In growth cone collapse, substratum choice and neurite outgrowth assays, Sema5A triggered an invariant inhibitory response in the context of L1, laminin, or netrin 1 signaling, suggesting that Sema5A inhibited retinal axons throughout their course at the optic disc and nerve. Antibody-perturbation studies in living embryo preparations showed that blocking of Sema5A function led to retinal axons straying out of the optic nerve bundle, indicating that Sema5A normally helped ensheath the retinal pathway. Thus, development of some CNS nerves requires inhibitory sheaths to maintain integrity. Furthermore, this function is accomplished using molecules such as Sema5A that exhibit conserved inhibitory responses in the presence of co-impinging signals from multiple families of guidance molecules.
A parallel splitting-up method for partial differential equations and its applications to Navier-Stokes equations (1992)

avec les conditions gnrales d'utilisation (
Discussion (1979)

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Prosodic Phrase Alignment for Machine Dubbing (2019)

Dubbing is a type of audiovisual translation where dialogues are translated and enacted so that they give the impression that the media is in the target language. It requires a careful alignment of dubbed recordings with the lip movements of performers in order to achieve visual coherence. In this paper, we deal with the specific problem of prosodic phrase synchronization within the framework of machine dubbing. Our methodology exploits the attention mechanism output in neural machine translation to find plausible phrasing for the translated dialogue lines and then uses them to condition their synthesis. Our initial work in this field records comparable speech rate ratio to professional dubbing translation, and improvement in terms of lip-syncing of long dialogue lines.
Liver Wedge Biopsy in Nonhuman Primates (1985)

The paper describes the surgical methodology of liver wedge biopsy based on techniques used in man.
Detection and Identification of Old World Leishmania by High Resolution Melt Analysis (2010)

This new technique is useful for rapid diagnosis of leishmaniasis and simultaneous identification and quantification of the infecting Leishmania species. It can be used for diagnostic purposes directly from clinical samples, as well as epidemiological studies, reservoir host investigations and vector surveys.
Simulation of Naphthalene Conversion in Biogas Initiated by Pulsed Corona Discharges (2009)

The numerical results on naphthalene removal in biogas are presented and compared with experiment. Plasma-chemical processes in discharge and post discharge stages are considered. The self-consistent approach for modeling of cleaning process on the basis of pulsed corona discharges is demonstrated. It has been revealed that the reaction of naphthalene (C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</sub> H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> ) with excited nitrogen molecule (N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> (A <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> Sigma)) is very important in the cleaning process in nitrogen-containing mixtures. The addition to N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> of CO, CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , and H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> results in the deterioration of treatment.
Development of an All-in-One Protein Digestion Platform Using Sorbent-Attached Membrane Funnel-Based Spray Ionization Mass Spectrometry (2020)

In this work, the sorbent-attached microfunnels used in funnel-based spray ionization mass spectrometry were evaluated for the all-in-one digestion of proteins. Sorbent materials, including C<sub>18</sub> and TiO<sub>2</sub> powders, were used as substrates to support in-funnel digestion and subsequent solid-phase extraction and purification of the digested products. In-funnel digestion protocols with and without reductive alkylation were developed for the analysis of proteins with and without disulfide linkages. Compared with in-solution digestion of the same loadings, the sequence coverage of in-funnel digestion of ovalbumin (with one disulfide bond) and ovocystatin (with two disulfide bonds) increased from 36% to 65% and from 21% to 81%, respectively. Loading 100 fmol of ovalbumin was sufficient to generate detectable tryptic fragments on C<sub>18</sub>-attached funnels. Notably, some phosphorylated digestion fragments were solely detected on C<sub>18</sub>-attached funnels and some nonphosphorylated digestion fragments were detected only on TiO<sub>2</sub>-attached funnels. Complex biological protein mixtures (i.e., bovine milk) and mouse liver protein extract could also be digested on C<sub>18</sub>- and TiO<sub>2</sub>-attached funnels. Using this platform, 30 samples were digested at the same time with enhanced digestion efficiency and were analyzed by funnel-based spray ionization mass spectrometry. This approach is potentially useful for sensitive and high-throughput bottom-up proteomic studies of complex biological samples.
Physiological and biochemical changes related to methyl jasmonate‐induced chilling tolerance of rice (<i>Oryza sativa</i> L.) seedlings (1996)

ABSTRACT Physiological and biochemical changes related to methyl jasmonate (MeJA)‐induced chilling tolerance of rice ( Oryza sativa L. cv. Taichung Native 1) seedlings were investigated. Treatment of whole plants with 10 mmol m −3 MeJA for 48 h before chilling (5 °C) was optimal for the induction of chilling tolerance. MeJA greatly improved the survival ratio of chilled seedlings and ameliorated chilling injury such as demolition of membrane structure (estimated by electrolyte leakage). MeJA also prevented water loss in chilled seedlings by reducing the opening of stomata and decreasing the root bleeding rate. Putrescine and spermine levels in shoots increased but spermidine levels decreased on exposure to MeJA. In roots, putrescine levels also increased and spermidine levels increased transiently on exposure to MeJA. Activities of arginine decarboxylase (ADC; EC 4.1.1.19) and S‐adenosylmethionine decarboxylase (SAMDC; EC 4.1.1.50) in both shoots and roots increased on exposure to MeJA, while the activity of ornithine decarboxylase (ODC; EC 4.1.1.17) remained unchanged. The MeJA‐induced putrescine increase was inhibited by 50 mmol m −3 α‐difluoromethylarginine (DFMA), an irreversible inhibitor of ADC, but not by 50 mmol m −3 α‐difluoromethylornithine (DFMO), an irreversible inhibitor of ODC. The effect of MeJA on the induction of chilling tolerance was also reduced by 50 mmol m −3 DFMA. The effects of DFMA were partly prevented by 1 mol m −3 putrescine. This indicates that putrescine accumulation is required for the induction of chilling tolerance of rice seedlings by MeJA.
Large-volume ionization chamber with variable apertures for air-kerma measurements of low-energy radiation sources (2006)

This report describes the design and initial measurement results of a large-volume ionization chamber designed to realize the air kerma from therapeutic radiation sources emitting photons with energies up to about 70 keV. The measured ionization current is used to provide absolute source calibrations by the most widely used brachytherapy source strength metric called air-kerma strength. The variable-aperture free-air chamber (VAFAC), named because of its variable aperture stand, will provide insight into the angular dependence of air-kerma strength measurements. Another unique feature of this ionization chamber is its seed holder design that reduces unwanted scatter, ensures vertical positioning, and rotates the seed with a positional accuracy of 0.3°. Benchmark experiments show that the VAFAC agrees well with existing National Institute of Standards and Technology standards and is capable of measuring clinical-strength seeds with repeatabilities of less than 2% at the 1σ level (k=1).
Cognitive functions and aging in the dog: Acquisition of nonspatial visual tasks. (1994)

Old, middle-aged, and young dogs were compared on discrimination and reversal learning and on acquisition of a delayed-nonmatching-to-sample (DNMS) test of recognition memory. DNMS acquisition was acquired more rapidly by young dogs. Reversal deficits were found between aged mixed-breed dogs and young beagles, but not between old and young beagles. Aged beagles also showed unexpected deficits in reward approach and object approach learning. Aged mixed-breed dogs did not show deficits in reward approach and object approach learning, but they learned the discrimination task more slowly than the age-matched beagles. A detailed analysis of response patterns indicated that once present, the development of side preferences contributed to deficits of old dogs in discrimination learning. In the discrimination reversal, old dogs were more persistent in responding to the previously rewarded stimulus object. Findings suggest that the dog, like other species, shows age-dependent deterioration in cognitive function, the extent of deterioration is a function of both task and previous experience, and at least part of the deterioration is a result of increased behavioral rigidity. Results also indicate that it is important to control for breed differences and previous experience.
Formal Techniques for SystemC Verification; Position Paper (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Triple Shockley type stacking faults in 4H-SiC epilayers (2009)

4 H -SiC epilayers have been characterized by microphotoluminescence (micro-PL) spectroscopy and micro-PL intensity mapping at room temperature. A type of stacking fault (SF) with a peak emission wavelength at 480 nm (2.58 eV) has been identified. The shape of this SF is triangular revealed by the micro-PL intensity mapping. Conventional and high-resolution transmission electron microscopies have been carried out to investigate the structure of this SF. Its stacking sequence is determined as (3,5) in Zhdanov’s notation, which is consistent with that of the triple Shockley SF. The formation mechanism of this SF is also discussed.
An Open-Label, Two-Arm, Phase I Trial of Recombinant Human Interleukin-21 in Patients with Metastatic Melanoma (2007)

IL-21 is biologically active at all dose levels administered and is generally well tolerated, and phase 2 studies have commenced using 30 microg/kg in the 5+9 regimen.
Residual stress conditions in laser-assisted machining (1999)

Summary The use of a laser beam upsets the thermal and therefore the energy balance of the cutting mechanism, which leads to reduced cutting force and tool wear. However, the most important aspect is the ability to control residual stresses. These are usually unfavourable in conventional machining but become favourable in laser machining. The ultimate is to carry out surface hardening in machining real-time.
Safety and Tolerability of N‐Acetylcysteine in Cocaine‐Dependent Individuals (2006)

A double-blind placebo-controlled crossover Phase I trial was conducted to assess the safety and tolerability of N-Acetylcysteine (NAC) in healthy, cocaine-dependent humans. Thirteen participants attended a three-day hospitalization in which they received placebo or NAC. Subjects were crossed over to receive the opposite medication condition during a second three-day hospitalization, which occurred the following week. Across placebo and NAC conditions, only mild side effects were noted, and the number of subjects reporting side effects did not differ. There were trends for a greater reduction in withdrawal symptoms and craving within the NAC condition. These preliminary results suggest that NAC is well tolerated in healthy, cocaine-dependent individuals and may reduce cocaine-related withdrawal symptoms and craving.
Carbon nanofiber/polyetherimide composite membranes with special dielectric properties (2009)

Negative dielectric constants in the frequency range from 10−2 to 107 Hz were gained from a type of carbon nanofiber/polyetherimide composite membranes with a thickness of ca. 20 µm, in particular, substantial negative values at the lower frequency region were discovered, which hold promise as an important resource for the preparation of meta-materials and their applications.
An interocular comparison of the multifocal VEP: a possible technique for detecting local damage to the optic nerve. (2000)

Local monocular damage to the ganglion cell/optic nerve can be quantitatively measured by an interocular comparison of the mVEP.
[Fat control--an effective antihypertensive strategy. Special recommendations for therapy of the overweight patient]. (1999)

Some 44% of all patients with elevated blood pressure are overweight. In obesity-related hypertension, sympathicotonia is regularly found, together with elevated intracellular calcium, sodium retention, increased cardiac output (per minute) and a sensitivity to salt. The role played by hyperinsulinemia has apparently been overstated. A primary rise in the minimal vascular resistance suffices to reduce the perfusion of the skeletal musculature and, solely on this basis, to induce insulin resistance. For the treatment of obesity-related hypertension, non-medicinal approaches to weight reduction predominate. Reducing the daily salt intake to 5 g can also bring about a measurable reduction in blood pressure. For the treatment with antihypertensive drugs, beta blockers and diuretics are the initial choice; in the case of pronounced metabolic syndrome, ACE-inhibitors and alpha-1 receptors.
Post‐transcriptional regulation of CspA expression in <i>Escherichia coli</i> (1996)

The Escherichia coli cspA gene, encoding the major cold-shock protein CspA, was deprived of its natural promoter and placed in an expression vector under the control of the inducible lambda PL promoter. After induction of transcription by thermal inactivation of the lambda ts repressor, abundant expression of the product (CspA) was obtained if the cells were subsequently incubated at 10 degrees C, but poor expression was obtained if the cells were incubated at 37 degrees C or 30 degrees C. The reason for this differential temperature-dependent expression was investigated and it was found that: (i) the CspA content of the cells decreased more rapidly at 37 degrees C compared to 10 degrees C, regardless of whether transcription was turned off by addition of rifampicin; (ii) both the chemical and functional half-lives of the cspA transcript were substantially longer at 10 degrees C compared to 37 degrees C; (iii) S30 extracts as well as 70S ribosomes prepared from cold-shocked cells translated CspA mRNA (but not phage MS2 RNA) more efficiently than equivalent extracts or ribosomes obtained from control cells grown at 37 degrees C; and (iv) purified CspA stimulated CspA mRNA translation. Overall, these results indicate that a selective modification of the cold-shocked translational apparatus favouring translation of CspA mRNA, and an increased stability of this mRNA at low temperature, may play an important role in the induction of cspA expression during cold shock.