gebhart/patrepeval huggingface dataset:
Light-scattering characterization of poly(tetrafluoroethylene). 2. PTFE in perfluorotetracosane: molecular weight distribution and solution properties (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLight-scattering characterization of poly(tetrafluoroethylene). 2. PTFE in perfluorotetracosane: molecular weight distribution and solution propertiesBenjamin Chu, Chi Wu, and Warren BuckCite this: Macromolecules 1989, 22, 2, 831–837Publication Date (Print):February 1, 1989Publication History Published online1 May 2002Published inissue 1 February 1989https://pubs.acs.org/doi/10.1021/ma00192a053https://doi.org/10.1021/ma00192a053research-articleACS PublicationsRequest reuse permissionsArticle Views686Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Primary Structure of Equine Serum Amyloid A (SAA) Protein (1989)

The complete amino acid sequence of equine serum amyloid A (SAA) was elucidated. The protein consists of 110 amino acid residues and contains an 8-amino acid residue insertion tentatively located between positions 69 and 70, as compared with human SAA. Microheterogeneities were detected at positions 16, 44, and 59, compatible with the existence of more than one SAA gene in the horse. This corresponds to the situation in man and mouse. Pronounced homology with SAA from man and several animal species was observed, thus confirming the conserved structure of this acute phase reactant and apoprotein of high-density lipoprotein (HDL).
Side-hole balloon-angioplasty catheters (1985)

The most difficult part of transluminal balloon angioplasty frequently is negotiating a guide wire and catheter through the diseased vessel lumen without creating a focal dissection or perforation. This is usually accomplished by first passing the lesion with a guide wire and small (5 or 6 French) catheter or Van Andel Teflon dilator and then exchanging a balloon catheter over the guide wire. A side hole near the tip of the catheter allows injection of contrast material around the wire forfluoroscopic visualization ofthe lumen during manipulation. This has been described by GrUntzig and Kampe [1 ] as an adjunct to Van Andel dilating catheters and by Barth [2] in the tip of balloon angioplasty catheters. These techniques produce opacification of the vessel distal to the catheter tip, but not proximally. In balloon angioplasty it is very useful to opacity the vessel proximal to the catheter tip. If a side hole is placed proximal to the balloon (upstream), injection of contrast medium defines the position of the balloon relative to the lesion during the procedure and allows visualization of the result without moving the catheter. It also allows the same distal visualization for guide-wire manipulation that is provided by a side hole in the catheter tip. The concept of a side hole proximal to the balloon is introduced by this communication.
Spreading Behavior and Morphology of Ethylene Methacrylic Acid (EMAA) Deposits via the Flame Spray Process (2012)

A single splat is the building block of a thermal spray coating; thus, investigating single splats is essential to understanding thermal spray coatings and their properties. In this study, the spreading behavior and the morphology of flame sprayed ethylene methacrylic acid (EMAA) splats, deposited at various stand-off distances (SODs) onto glass and mild steel substrates were investigated using optical microscopy, back scattered scanning electron microscopy and secondary electron scanning electron microscopy. The results of this study indicate that the spread factor increases with an increase in the stand-off distance up to 30 cm for glass and 25 cm for steel substrates. Further increase of the stand-off distance results in a decreased spread factor. The aspect ratio of EMAA single splats on both glass and mild steel substrates decreases with increased stand-off distances, indicating that more circular shapes occur at higher stand-off distances. On mild steel substrates, the minimum unevenness ratio (η) occurs at 35 cm SOD. The unevenness ratio (η) on glass substrates decreases from 1.9 (at 20 cm SOD) to 1.77 (at 25 cm SOD), and from 1.8 (at 30 cm SOD) to 1.3 (at 35 cm SOD). The lowest unevenness ratio (η) is found at 35 cm SOD. The highest unevenness ratio (η) is at 25 cm SOD. This paper discusses the effect of surface chemistry on the underside of an EMAA single splat morphology. It includes Raman spectrum analysis of EMAA and the X-ray diffraction of the EMAA powder. This work analyses the splat morphology and classifies the taxonomy of single splats of EMAA.
Neuronal Nitric Oxide Synthase (1995)

A gene coding for rat neuronal nitric oxide synthase (nNOS) has been cloned into pCWori and the vector has been expressed in Escherichia coli. The expressed enzyme has been purified with a final yield of purified protein of approximately 1 mg/g of wet cells. The recombinant protein reconstituted with calmodulin and Ca2+ exhibits spectroscopic and catalytic properties identical to those reported in the literature for nNOS. Reaction of recombinant nNOS with phenyldiazene produces a phenyl-iron (Fe.Ph) complex with a maximum at 470 nm. Formation of this complex is paralleled by inactivation of the enzyme and is inhibited by arginine, the natural substrate of the enzyme. Phenyl-iron complex formation does not alter the rate of electron transfer from the flavin domain to cytochrome c. Addition of ferricyanide triggers migration of the phenyl residue from the iron to the porphyrin nitrogens. The N-phenylprotoporphyrin isomers with the phenyl on the nitrogens of pyrrole rings B, A, C, and D are formed in, respectively, approximately a 14:20:21:45 ratio. The regioisomer pattern indicates that the active site of NOS is open to some extent above all four pyrrole rings but more so above pyrrole ring D. Arylhydrazines are thus not only a new class of inhibitors of nNOS but provide useful information on the active site topology of the enzyme.
Plastic Optical Fiber Sensors for Measurement of Large Strain in Geotextile Materials (2008)

A high-strain optical fiber sensor system has been developed to provide a cost-effective solution for measurement of very large strain. The measurement of large strain in the order of a few tens of % strain (up to 40 % strain) in geotextile materials has been achieved using an extrinsic plastic optical fiber sensor (POF). Based on this design, the sensor is not limited to operating within the elastic region of the plastic fiber proposed by other workers in the field. The present design allows for compression strains to be measured even after exceeding strain levels of 5% (typical plastic strain values of POFs based on fiber stretching.) The POF were initially calibrated using a linear variable displacement transducer and the results based on tensile tests of a series of geotextile fabrics have shown to compare well with other reference measurements.
Strategies for measurement of atmospheric column means of carbon dioxide from aircraft using discrete sampling (2003)

Automated flask sampling aboard small charter aircraft has been proposed as a low‐cost, reliable method to greatly increase the density of measurements of CO 2 mixing ratios in continental regions in order to provide data for assessment of global and regional CO 2 budgets. We use data from the CO 2 Budget and Rectification‐Airborne 2000 campaign over North America to study the feasibility of using discrete (flask) sampling to determine column mean CO 2 in the lowest 4 km of the atmosphere. To simulate flask sampling, data were selected from profiles of CO 2 measured continuously with an onboard (in situ) analyzer. We find that midday column means can be determined without bias relative to true column means measured by the in situ analyzer to within 0.15 and better than 0.10 ppm by using 10 and 20 instantaneously collected flask samples, respectively. More precise results can be obtained by using a flask sampling strategy that linearly integrates over portions of the air column. Using less than 8–10 flasks can lead to significant sampling bias for some common profile shapes. Sampling prior to the breakup of the nocturnal stable layer will generally lead to large sampling bias because of the inability of aircraft to probe large CO 2 gradients that often exist very close to the ground at night and during the early morning.
Generalized pencil-of-function method for extracting poles of an EM system from its transient response (1989)

A generalized pencil-of-function (GPOF) method is developed for extracting the poles of an electromagnetic system from its transient response. The GPOF method needs the solution of a generalized eigenvalue problem to find the poles. Subspace decomposition is also used to optimize the performance of the GPOF method. The GPOF method has advantages over the Prony method in both computation and noise sensitivity, and approaches the Cramer-Rao bound when the signal-to-noise ratio (SNR) is above threshold. An application of the GPOF method to a thin-wire target is presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Nonlinear Ultrasonics: Signal Processing Considerations and a Nonlinear Parameter for Rayleigh Waves (2005)

An effective way to describe changes in the microstructure of a material or\nto assess fatigue damage at an early stage in fatigue life is by measuring the acoustic\nnonlinearity parameter beta. The nonlinearity parameter is defined for harmonic\nlongitudinal plane waves and it depends on the ratio of the amplitudes of the first\nharmonic of the exciting signal and the second harmonic. A reliable measurement\nof the amplitudes of these harmonics is crucial since their amplitude of the second\n(higher) harmonic is much smaller than the amplitude of the first harmonic.\nThis research investigates the influence of the apparent nonlinearity that can occur\ndue to the signal processing and shows how this influence can be quantified and\nminimized to enable a more accurate evaluation of the acoustic nonlinearity parameter.\nFurthermore the concept of the nonlinear parameter is extended to Rayleigh surface\nwaves by developing a connection between the harmonic amplitudes and the third\norder elastic constants, using the approximate model by Zabolotskaya.\nFinally the problem of modeling the influence of fatigue damage on the nonlinear\nparameter and the elastic constants is discussed.\nThe reduction of the processing nonlinearity combined with Rayleigh surface waves\n- Rayleigh surface waves are more efficient in the detection of fatigue damage initiated\nand concentrated at the surface - helps improve the prediction of fatigue damage and\nthe remaining life of a sample.
Thiol-Specific Cross-Linkers of Variable Length Reveal a Similar Separation of SH1 and SH2 in Myosin Subfragment 1 in the Presence and Absence of MgADP (1999)

A series of thiol-specific cross-linking reagents were prepared for studying the kinetics of cross-linking between SH1 (Cys(707)) and SH2 (Cys(697)) in rabbit skeletal muscle myosin subfragment 1. The reagents were of the type RSS(CH(2))(n)()SSR, with R = 3-carboxy-4-nitrophenyl and n = 3, 6, 7, 8, 9, 10, and 12, spanning distances from 9 to 20 A. The reactions were monitored spectrophotometrically by measuring the release of 2-nitro-5-thiobenzoate. Reaction rates for modification of SH1 (k(1)) and for cross-linking (k(2)) were measured by the decrease of the K(+)(EDTA)-ATPase activity and the decrease of the Ca(2+)-ATPase activity, respectively, and corrected for the different reactivities of C(n). Cross-linking rates in the presence and absence of MgADP showed similar dependence on the length of the reagents: While the cross-linking rates for n = 3 or n = 6 were close to those for n = 0 (Ellman's reagent), those for n = 7 and 8 were significantly increased. Thus the distance between SH1 and SH2 appears to be equal in both states and can be estimated as >/=15 A, based on the length of the reagent with n = 8 in stretched conformation. Under rigor conditions, reactivity of SH1 differed significantly from that in the presence of MgADP, presumably because of shielding through a lipophilic domain. Similarly, the cross-linking rates k(2) for C(3), C(6), and C(7) in the absence of MgADP were ca. 15 times lower than in the presence of MgADP, suggesting a change in the structure of the SH2 region that depends on nucleotide binding. The results are discussed in terms of recent X-ray structures of S1 and S1-MgADP [Rayment et al. (1993) Science 261, 50-58; Gulick et al. (1997) Biochemistry 36, 11619-11628].
Productive Objects: An Applied Software Project Management Framework (1997)

Part One: Systems and Projects Part Two: Process Part Three: Plan And Scope Part Four: Schedule Part Five: Risk Part Six: Software Development Part Seven: Tools Part Eight: Change Part Nine: Procurement Part Ten: Organization Part Eleven: Resources Part Twelve: Cost Part Thirteen: Communication
[Taxol and related diterpenoids of Taxus sp.: important acquisitions in the treatment of cancer]. (1993)

Phytochemical and pharmacological studies on Taxus sp extracts have resulted in the isolation and the identification of several diterpenoids, and the discovery of the potent antitumor activity of taxol. This natural compound displays a unique mechanism of action as it stabilizes microtubules and inhibits their depolymerization into free tubulin. The emergence of taxol from the screening of natural products shows the benefits and the potent interest of these constituents in the search of drugs exhibiting novel mechanisms of action. The most pressing problem in taxol or taxol derivates commercialization is the drug supply. Alternative sources of taxol are now under investigation, mainly the total synthesis of taxol, the hemisynthesis of taxol or of taxotere from 10-deacetylbaccatine III, the in vitro production of taxol by cell or tissue cultures, and the prospection of new natural sources of taxol.
Voltage-dependent calcium channels in pituitary cells in culture. I. Characterization by 45Ca2+ fluxes. (1984)

Properties of Ca2+ transport activated by depolarization of the membrane potential were investigated in the GH4C1 strain of rat pituitary cells. Membrane potential was depolarized by increasing external K+ concentration and was determined by [3H]tetraphenylphosphonium+ distribution. Depolarization by 50 mM [K+]o increased the initial rate of 45Ca2+ uptake 5-fold and the steady state 45Ca2+ content 8-fold. Stimulated 45Ca2+ uptake was not inhibited by tetrodotoxin (2 X 10(-6) M), and was insensitive to external Na+ concentration. Stimulated 45Ca2+ uptake increased with increasing external Ca2+ concentration (for [Ca2+]o less than 10 mM) and could be described by a Langmuir type expression (KCa = 4.3 mM). Initial rates of 45Ca2+ uptake increased almost linearly between -51 and -30 mV, from 2 to 12 nmol/min/mg of protein, and a maximum of 14 nmol/min/mg of protein was reached at -12 mV beyond which 45Ca2+ influx decreased, and was 11 nmol/min/mg of protein at 0 mV. Ca2+ permeability, PCa, calculated from the Goldman-Hodgkin-Katz constant field expression increased almost linearly for a wide range of membrane potential (-51 to -20 mV) and began to level off at -6 mV. Activated 45Ca2+ uptake was completely inhibited by La3+, Co2+, Mn2+, Mg2+, nifedipine, and verapamil; K1/2 values for inhibition were 1.7 X 10(-7) M, 0.1 mM, 0.1 mM, 2 mM, 1.7 X 10(-8) M, and 2 X 10(-5) M, respectively, at 0.5 mM [Ca2+]o. Ba2+ could substitute for Ca2+ in the uptake mechanism. The increase in activated 45Ca2+ uptake was transient and was turned off with time. We conclude that the initial rate of K+-stimulated 45Ca2+ uptake measured under the experimental conditions described represents uptake via voltage-dependent Ca2+ channels. Knowledge of the properties of this channel in GH4C1 cells will be essential in elucidating its role in the Ca2+-dependent actions of thyrotropin-releasing hormone.
Correction of phase extraction error in phase-shifting interferometry based on Lissajous figure and ellipse fitting technology (2015)

The accuracy of phase-shifting interferometers (PSI) is crippled by nonlinearity of the phase shifter and instability of the environment such as vibration and air turbulence. A general algorithm, utilizing Lissajous figures and ellipse fitting, of correcting the phase extraction error in the phase shifting interferometry is described in this paper. By plotting N against D, where N and D represent the numerator and denominator terms of the phase extraction function (i.e. an arctangent function) respectively, a Lissajous ellipse is created. Once the parameters of the ellipse are determined by ellipse fitting, one can transform the ellipse to a unit circle (ETC). Through this process the phase extraction error caused by random phase shift errors can be corrected successfully. Proposed method is non-iterated, adapts to all phase shifting algorithms (PSAs), and has high accuracy. Some factors that may affect the performance of proposed method are discussed in numerical simulations. Optical experiments are implemented to validate the effectiveness of proposed algorithm.
ARMin - Exoskeleton for Arm Therapy in Stroke Patients (2007)

Task-oriented repetitive movement can improve movement performance in patients with neurological lesions. The application of robotics can serve to assist, enhance, evaluate and document rehabilitation of movements. ARMin is a robot for arm therapy applicable to the arm training in clinics. It has an exoskeleton structure and is equipped with position and force sensors. Our latest version ARMin II has six degrees of freedom. The mechanical structure, the actuators, and the sensors of the robot are optimized for patient-cooperative control strategies based on impedance and admittance architectures. The device can work in three therapy modes: passive mobilization, game therapy, and task-oriented training. This paper presents the technical components of the new version ARMin II, the therapy modes, the control strategy for a new example of a game therapy, and clinical results of a pilot study with 11 chronic stroke patients and of single case studies conducted with three chronic stroke patients.
A Case of Sodium Oxybate Treatment of Tardive Dyskinesia and Bipolar Disorder (2008)

Article AbstractLetter to the Editor Sir: Sodium oxybate is increasingly being used off-labelto treat the fibromyalgia syndrome defined by pain, fatigue,nonrefreshing sleep, and fluency loss. This compound has acomplicated mechanism of action with agonist binding on?-aminobutyric acid (GABA)-B receptor, agonist binding on the?-hydroxybutyrate (GHB) receptor, and possible stoichiometricsignaling effects as an intermediary in GABA and glutamatemetabolism. Its clinical effect is a profound increase in the durationof stage III and IV slow wave sleep. This case describesa profound effect of oxybate on bipolar disorder and tardivedyskinesia presenting jointly with fibromyalgia.
Large scale microcomponents assembly using an external magnetic array (2007)

Assembly of 2500 microcomponents has been accomplished in 5min with assembly yield of 97% by combining magnetic force, shape recognition, and vibration. The host substrate has been patterned with physical cavities having the shape of the target chip and positioned on top of a master substrate which is an 8in. wafer having array of magnets embedded in it. The chip has been modified by depositing a soft magnetic film (CoNiP) on its back side. By the competition between the magnetic force and the mechanical force, microcomponents have been assembled with their active side facing up.
Curious Work (2016)

WA.OA414 Anonymous, English—Embroidered picture: The Sacrifice of Isaac, dated 1673,©Ashmolean Museum, University of Oxford
BASIC CAUSES OF FAILURE (1989)

The greatest boon to public education will come through an improvement in social conditions. Strange as it may seem, elimination of unemployment will help our schools immeasurably. Passage of a national health plan will improve the well-being of the pupils, mentally as well as physically. Well-nourished and healthy students will provide fewer discipline problems. Furthermore, a federal campaign to provide low-cost housing would help to ameliorate the deplorable conditions in which many children live. Plants cannot grow well in barren ground. In short, our schools cannot improve until the nation as a whole emerges from poverty and desperation of deprived Americans.
An investigation of CuCr contact materials with low chopping current (2002)

In this paper, the chopping current, interruption capability and dielectric strength of CuCr, CuCrWC and CuCrTeSe contact materials are measured. Experimental results show that the addition of WC, Te, Se to CuCr alloys can reduce the chopping current, and at the same time has little influence on the interruption capability. Furthermore, the dielectric strength of CuCr alloys will increase when WC is added to alloys, while the addition of Te, Se to CuCr alloy will decrease the dielectric strength to some extent. The composition, microstructure and alloy element scatter of these alloys before and after arcing are measured by scanning electron microscopy (SEM). The effect of WC, Te, Se in CuCr alloys is investigated preliminarily.
The Development of the Wheel Loader: A Case Study in Technology (1995)

While the nature of technology and the process of innovation are both important to engineers, few ever give them much conscious thought. As they are both pertinent to this conference and presently the subject of argument in other parts of NZ some of the important features of technological development are presented using as an illustration the history of the wheel loader (or front-end-loader).
Angiotensin-converting enzyme inhibitors: importance of the amide carbonyl of mercaptoacyl amino acids for hydrogen bonding to the enzyme (1982)

A series of mercaptoacyl amino acids and related compounds was synthesized and evaluated for inhibition of angiotensin-converting enzyme (ACE) in order to determine the nature and importance of the putative interaction between ACE and the amide moiety of inhibitors such as captopril (3-mercapto-2-methylpropanoyl-L-proline). It was concluded that the interaction involves a hydrogen bond from a donor site on ACE to the oxygen of the amide carbonyl. Compounds in which the amide moiety is replaced by other groups (ester, ketone, sulfonamide) capable of accepting a hydrogen bond are effective inhibitors, but compounds in which only the geometrical features of the amide are retained are ineffective inhibitors. The presence of an NH group is not necessary for effective inhibition. The activity of a series of mercaptoacyl cycloalkyl carboxylic acids parallels the activity of the isosteric series of mercaptoacyl imino acids.