gebhart/patrepeval huggingface dataset:
Working the Net: breaking the modem bottleneck—on the cheap (1998)

article Working the Net: breaking the modem bottleneck—on the cheap Share on Author: Jill H. Ellsworth Oak Ridge Research Oak Ridge ResearchView Profile Authors Info & Claims netWorkerVolume 2Issue 5Dec. 1998 pp 23–26https://doi.org/10.1145/289165.289173Online:01 November 1998Publication History 0citation172DownloadsMetricsTotal Citations0Total Downloads172Last 12 Months0Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Towards supporting awareness of indirect conflicts across software configuration management workspaces (2007)

Workspace awareness techniques have been proposed to enhance the effectiveness of software configuration management systems in coordinating parallel work. These techniques share information regarding ongoing changes, so potential conflicts can be detected during development, instead of when changes are completed and committed to a repository. To date, however, workspace awareness techniques only address direct conflicts, which arise due to concurrent changes to the same artifact, but are unable to support indirect conflicts, which arise due to ongoing changes in one artifact affecting concurrent changes in an-other artifact. In this paper, we present a new, cross-workspace awareness technique that supports one particular kind of indirect conflict, namely those indirect conflicts caused by changes to class signatures. We introduce our approach, discuss its implementation in our workspace awareness tool Palantír, illustrate its potential through two pilot studies, and lay out how to generalize the technique to a broader set of indirect conflicts
A Very Low Power MAC (VLPM) Protocol for Wireless Body Area Networks (2011)

Wireless Body Area Networks (WBANs) consist of a limited number of battery operated nodes that are used to monitor the vital signs of a patient over long periods of time without restricting the patient's movements. They are an easy and fast way to diagnose the patient's status and to consult the doctor. Device as well as network lifetime are among the most important factors in a WBAN. Prolonging the lifetime of the WBAN strongly depends on controlling the energy consumption of sensor nodes. To achieve energy efficiency, low duty cycle MAC protocols are used, but for medical applications, especially in the case of pacemakers where data have time-limited relevance, these protocols increase latency which is highly undesirable and leads to system instability. In this paper, we propose a low power MAC protocol (VLPM) based on existing wakeup radio approaches which reduce energy consumption as well as improving the response time of a node. We categorize the traffic into uplink and downlink traffic. The nodes are equipped with both a low power wake-up transmitter and receiver. The low power wake-up receiver monitors the activity on channel all the time with a very low power and keeps the MCU (Micro Controller Unit) along with main radio in sleep mode. When a node [BN or BNC (BAN Coordinator)] wants to communicate with another node, it uses the low-power radio to send a wakeup packet, which will prompt the receiver to power up its primary radio to listen for the message that follows shortly. The wake-up packet contains the desired node's ID along with some other information to let the targeted node to wake-up and take part in communication and let all other nodes to go to sleep mode quickly. The VLPM protocol is proposed for applications having low traffic conditions. For high traffic rates, optimization is needed. Analytical results show that the proposed protocol outperforms both synchronized and unsynchronized MAC protocols like T-MAC, SCP-MAC, B-MAC and X-MAC in terms of energy consumption and response time.
A novel tungsten light-shield structure for high-density CCD image sensors (1991)

A novel tungsten light-shield structure has been developed. Tungsten film properties, the device configuration with the tungsten light-shield structure, and experimentally achieved results regarding device characteristics are described. Optical measurement clarified that tungsten film has a sufficiently low transmittance value for practical use for more than 200-nm-thick film and is stable up to 1000 degrees C. The good step coverage and low reflectance, such as 20-40% for aluminum, required for light-shield film were also obtained. A tungsten light-shield structure was applied to a 1/2-in format 668(H)-pixel*575(V)-pixel charge coupled-device (CCD) image sensor. An extremely low smear value, less than 0.001%, was obtained for a 300-nm film thickness.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Complete amino acid sequence of the B875 light‐harvesting protein of <i>Rhodopseudomonas sphaeroides</i> strain 2.4.1 (1985)

The complete amino acid sequence was determined for the alpha- and beta-chains of the B875 light-harvesting protein purified from photosynthetic membranes of Rhodopseudomonas sphaeroides 2.4.1. The sequence of the B875-alpha-polypeptide was identical to that reported for the R26.1 carotenoidless mutant [(1985) Biochim. Biophys. Acta 806, 185-186] and contained 58 amino acid residues with a blocked methionine and a glutamic acid at the N- and C-termini, respectively. The B875-beta-polypeptide contained 48 amino acid residues with alanine and phenylalanine as respective N- and C-termini; although otherwise identical, the leucine at position 29 in the wild-type strain was replaced by proline in the mutant. This radical amino acid substitution occurred within the central hydrophobic domain of the beta-polypeptide chain and is thought to result in a weakening of the structure of the alpha/beta heterodimer since it was not possible to isolate the intact pigment-protein complex from the R26.1 mutant strain.
Amino Acid Transport System of the Guinea Pig Small Intestine is Injured by Hydroxyl Radicals (1993)

The mechanism for the damage to the alanine-preferring amino acid transport system (A system) of guinea pig intestinal brush border membrane vesicles induced by active oxygen species was studied in vitro. The transport activity of L-proline, which is a model amino acid for the A system, and the tryptophan fluorescence intensity of intestinal brush border membrane vesicles were decreased, and lipid peroxidation of these membrane vesicles was induced by ultraviolet irradiation, which generated active oxygen species. Thiourea (hydroxyl radical scavenger) protected L-proline transport activity and tryptophan fluorescence intensity of intestinal brush border membrane vesicles and also inhibited lipid peroxidation in these membrane vesicles in the presence of active oxygen radicals. alpha-Tocopherol (singlet oxygen radical scavenger) inhibited lipid peroxidation of intestinal brush border membrane vesicles but protected neither L-proline transport activity nor tryptophan fluorescence intensity in these membrane vesicles in the presence of active oxygen radicals. Catalase and superoxide dismutase showed no protective effect on L-proline transport activity, tryptophan fluorescence intensity, or lipid peroxide formation in intestinal brush border membrane vesicles in the presence of active oxygen radicals.(ABSTRACT TRUNCATED AT 250 WORDS)
Prolonged Antagonism of Opioid Action with Intravenous Nalmefene in Man (1986)

To identify the opioid antagonist activity of nalmefene and to determine its duration in man, six healthy male subjects were pretreated on separate days with a saline placebo, 0.5 mg, 1 mg, or 2 mg nalmefene intravenously in a randomized double-blind fashion. Opioid challenges with fentanyl, 2 micrograms/kg, then were administered 1, 2, 4, 6, and 8 h afterward. Respiratory depression was monitored by ventilatory and occlusion pressure responses during CO2 rebreathing, while analgesia to experimental pain was identified with the submaximal effort tourniquet ischemia test. One hour following placebo pretreatment, the initial fentanyl dose produced marked respiratory depression. Minute ventilation and occlusion pressure at a PCO2 60 mmHg during rebreathing (VE60 and P(0.1)60) were reduced to 29 and 41% of control, respectively. The slopes of the ventilatory and occlusion pressure responses also decreased significantly to 51 and 55% of control. Respiratory effects were similar with all subsequent fentanyl doses. Pretreatment with 2 mg nalmefene completely prevented the subjective and respiratory effects of fentanyl for the entire 8 h of the experiment. Nalmefene, 1 mg, significantly blunted the fentanyl effects for the same period, but VE60 values at 6 and 8 h were depressed significantly (P less than 0.05) to 66 and 61% of control. The antagonist effects of the lowest nalmefene dose, 0.5 mg, persisted for about 4 h, at which time VE60 was 64% of control. Fentanyl administration produced consistent increases in pain tolerance (44-55% above control) throughout the experiment. Nalmefene pretreatment abolished this analgesic response in a dose-related time course that mirrored the respiratory effects almost exactly.(ABSTRACT TRUNCATED AT 250 WORDS)
Clinical management of coeliac disease (2011)

In conclusion, CD is one of the most common immune-mediated disorders in the Western world. It should be considered in patients with a number of varying GI and non-GI symptoms, as well as in high-risk groups that include first-degree relatives.
Does modulation of organic cation transporters improve pralidoxime activity in an animal model of organophosphate poisoning?* (2011)

Pralidoxime is secreted in rats and mice by renal Oct1 and/or Oct2 but not by Oct3. Modulation of organic cation transporter activity increased the plasma pralidoxime concentrations and the antidotal effect of pralidoxime with sustained return within the normal range of respiratory variables in paraoxon-poisoned rats. These results suggest a promising approach in an animal model toward the increase in efficiency of pralidoxime. However, further studies are needed before these results are extended to human poisoning.
Importance of Basic Residues and Quaternary Structure in the Function of MIP-1β:  CCR5 Binding and Cell Surface Sugar Interactions (2001)

Chemokines direct immune cells toward sites of infection by establishing a gradient across the extracellular matrix of the tissue. This gradient is thought to be stabilized by ligation of chemokines to sulfated polysaccharides known as glycosaminoglycans (GAGs) that are found on the surface of endothelial and other cells as well as in the tissue matrix. GAGs interact with chemokines and in some cases cause them to aggregate. The interaction between cell surface GAGs and chemokines has also been postulated to play a role in the anti-HIV activity of some chemokines, including MIP-1beta. Since many proteins interact with GAGs by utilizing basic residues, we mutated R18, K45, R46, and K48 in MIP-1beta to investigate the role of these residues in GAG binding and CCR5 function. We find that no single amino acid substitution alone has a dramatic effect on heparin binding, although change at R46 has a moderate effect. However, binding to heparin is completely abrogated in a mutant (K45A/R46A/K48A) in which the entire "40's loop" has been neutralized. A functional study of these mutants reveals that the charged residues in this 40's loop, particularly K48 and R46, are critical mediators of MIP-1beta binding to its receptor CCR5. However, despite the partially overlapping function of the residues in the 40's loop in binding to both CCR5 and heparin, the presence of cell surface sugars does not appear to be necessary for the ability of MIP-1beta to function on its receptor CCR5, as enzymatic removal of GAGs from cells results in little effect on MIP-1beta activity. Because the means by which the chemokine gradient transmits information to the recruited cells is not well defined, we also mutated the basic residues in MIP(9), a truncated form of MIP-1beta that is impaired in its ability to dimerize, to probe whether the quaternary structure of this chemokine influences its ability to bind heparin. None of the truncated variants bound as well as the full-length proteins containing the same mutation, suggesting that the MIP-1beta dimer participates in heparin binding.
Iron‐Catalyzed α‐Alkylation of Ketones with Alcohols (2015)

A general and benign iron-catalyzed α-alkylation reaction of ketones with primary alcohols has been developed. The key to success of the reaction is the use of a Knölker-type complex as catalyst (2 mol %) in the presence of Cs2 CO3 as base (10 mol %) under hydrogen-borrowing conditions. Using 2-aminobenzyl alcohol as alkylation reagent allows for the "green" synthesis of quinoline derivatives.
Metallographic and Materialographic Specimen Preparation, Light Microscopy, Image Analysis and Hardness Testing (2007)

Description Twenty-seven comprehensive chapters cover all important aspects of the metallographic and materialographic specimen preparation process, light microscopy, image analysis, hardness testing, and directions for establishing and maintaining a modern metallographic/materialographic laboratory. Part I is description of sectioning, mounting, grinding, polishing, and etching of specimens for examination in reflected light, enabling the reader to understand the mechanisms of the entire preparation process. Part II is a "hands-on" manual guiding the metallographer and materialographer to the correct preparation method, based on the material to be prepared and on the purpose of examination. More than 150 methods are indicated covering practically all types of materials, describing the preparation process from sectioning to etching. This part also includes a section on trouble shooting, covering all stages in the preparation process and artifacts developed during the preparation. Part III is a description of the optical reflected-light microscope with photomicroscopy giving the reader both an introduction to the subject and a manual for the daily work. Part IV is an introduction to quantitative microstructural analysis and automatic image analysis, both theoretically and practically with emphasis on the examinations based on ASTM standards and other types of commonly used analyses. Part V is a description of the most used hardness methods based on ASTM standards. Also other methods like instrumented indentation testing are described. Part VI gives directions on how to establish and maintain a modern metallographic/materialographic laboratory. The important rules and regulations covering occupational safety are described and commented on.
Modeling Results of On- and Off-time B and dB/dt for Time-domain Airborne EM Systems (2008)

Airborne time-domain EM modeling generally uses the convolution of the transmitting current with the system responses. However, if no special attention is paid to the singularity of the system responses, serious stability problem may occur in the modeling of on-time and off-time magnetic induction B and time-derivative of magnetic induction dB/dt. In this paper, after a through investigation of different convolution modes, we choose a stable algorithm for modeling the responses of time-domain airborne EM systems, where the step response of the airborne EM system is calculated and convolved with the transmitting current by Gaussian quadratures. While the algorithm can be used for any arbitrary transmitting waveforms, we choose a half-sine and trapezoid wave as an example. The preliminary results for a half-space model show a clearly consistent integral-derivative relationship between the B and dB/dt responses.
The effect of antiplasticization on secondary loss transitions and permeability of polymers (1969)

Abstract Antiplasticizers are considered to be diluents which when added to polymers result in mechanical property behavior opposite to that of plasticization. The addition of antiplasticizers to certain polymers such as Bisphenol A polycarbonate, polysulfone, and polyvinyl chloride results in the elimination of the secondary loss transitions of these polymers. As a drop in modulus accompanies these transitions, their elimination results in higher tensile strength and tensile modulus. As secondary transitions are commonly associated with ductility and impact strength, their elimination also results in the observed embrittlement characteristics. The addition of anti‐plasticizers to polymers also restricts the diffusion of penetrants resulting from the decrease of molecular flexibility in the polymer matrix.
Quantitative evaluation of<i>Escherichia coli</i>host strains for tolerance to cytosine methylation in plasmid and phage recombinants (1989)

Many strains of E. coli K12 restrict DNA containing cytosine methylation such as that present in plant and animal genomes. Such restriction can severely inhibit the efficiency of cloning genomic DNAs. We have quantitatively evaluated a total of 39 E. coli strains for their tolerance to cytosine methylation in phage and plasmid cloning systems. Quantitative estimations of relative tolerance to methylation for these strains are presented, together with the evaluation of the most promising strains in practical recombinant cloning situations. Host strains are recommended for different recombinant cloning requirements. These data also provide a rational basis for future construction of 'ideal' hosts combining optimal methylation tolerance with additional advantageous mutations.
Chiral Diketimines as Ligands in Pd-Catalyzed Reactions:  Prediction of Catalyst Activity by the AMS Model (2000)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTChiral Diketimines as Ligands in Pd-Catalyzed Reactions: Prediction of Catalyst Activity by the AMS ModelManfred T. Reetz, Gerd Haderlein, and Klaus AngermundView Author Information Max-Planck-Institut für Kohlenforschung Kaiser-Wilhelm-Platz 1 D-45470 Mülheim/Ruhr, Germany Cite this: J. Am. Chem. Soc. 2000, 122, 5, 996–997Publication Date (Web):January 21, 2000Publication History Received23 August 1999Revised1 December 1999Published online21 January 2000Published inissue 1 February 2000https://doi.org/10.1021/ja9930566Copyright © 2000 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views655Altmetric-Citations80LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (204 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Catalysts,Ligands,Palladium,Palladium complexes,Transition metals Get e-Alerts
Dextran Sulfate Protects Pancreatic β-Cells, Reduces Autoimmunity, and Ameliorates Type 1 Diabetes (2020)

A failure in self-tolerance leads to autoimmune destruction of pancreatic β-cells and type 1 diabetes (T1D). Low-molecular-weight dextran sulfate (DS) is a sulfated semisynthetic polysaccharide with demonstrated cytoprotective and immunomodulatory properties in vitro. However, whether DS can protect pancreatic β-cells, reduce autoimmunity, and ameliorate T1D is unknown. In this study, we report that DS, but not dextran, protects human β-cells against cytokine-mediated cytotoxicity in vitro. DS also protects mitochondrial function and glucose-stimulated insulin secretion and reduces chemokine expression in human islets in a proinflammatory environment. Interestingly, daily treatment with DS significantly reduces diabetes incidence in prediabetic NOD mice and, most importantly, reverses diabetes in early-onset diabetic NOD mice. DS decreases β-cell death, enhances islet heparan sulfate (HS)/HS proteoglycan expression, and preserves β-cell mass and plasma insulin in these mice. DS administration also increases the expression of the inhibitory costimulatory molecule programmed death-1 (PD-1) in T cells, reduces interferon-γ<sup>+</sup>CD4<sup>+</sup> and CD8<sup>+</sup> T cells, and enhances the number of FoxP3<sup>+</sup> cells. Collectively, these studies demonstrate that the action of one single molecule, DS, on β-cell protection, extracellular matrix preservation, and immunomodulation can reverse diabetes in NOD mice, highlighting its therapeutic potential for the treatment of T1D.
Improving performance of phase shift pulse BOTDR (2017)

We propose a phase shift pulse BOTDR (PSP-BOTDR) using probes composed of long and short pulses with phase shift keying modulation, and evaluate its performance by experiment and simulation. Modifying the previous probe configuration reduces signal leakage from the adjacent section to a negligible extent, and achieves truely a spatial resolution of 20 cm.
Solutions to the Problems of High-Temperature Irradiation Embrittlement (1967)

The effects of irradiation on high-temperature mechanical properties of structural materials is described using Type 304 stainless steel as an example. The general effect is one in which the grain-boundary fracture process, but not the deformation process, is affected. The data suggest the primary cause to be helium generated from (n,α) reactions. Several metallurgical techniques for improving the ductilities of irradiated alloys are suggested, and experimental data on Type 304 stainless steel are given for which the degree of improvement is demonstrated.
A two-level classifier for fingerprint recognition (1991)

A PC-based two-level classifier for fingerprint recognition is presented. Input fingerprint images are preprocessed via Laplacian edge detector and a skeletonization algorithm. The thinned binary image is then classified into one of the four categories of fingerprint via a curve tracing algorithm and a scoring method. Local density of the designated area is then computed for the second-level classification (i.e. within category classification). The proposed method is found to be reliable for a small set of fingerprints.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>