gebhart/patrepeval huggingface dataset:
[Primary hyperparathyroidism. An analysis of 152 patients with special references to acute life threatening complications (acute hyperparathyroidism)]. (1976)

The findings of 152 patients with proven primary hyperparathyroidism are reportedmthe purpose of the analysis was to find difference between the various clinical manifestations of the disease. Furthermore the occurrence of acute hyperparathyroid crisis in our series as well as in the literature are described. 65.8% of the patients were females, 34.2% were males. The leading symptom in 98 patients (group I) were kidney stones and in 23 patients (group II) cystic bone disease. Both manifestations of the disease occurred in only 7 patients (group III) and no symptoms related to the kidneys or to the bones occurred in 24 patients (group IV). Because of the difference of the clinical manifestations the additional data were analyzed for each group separately and compared with each other. There was no difference in the mean serum calcium levels for all four groups, however, patients of group I were on the average younger, the duration of the disease was longer and the weight of the parathyroid adenoma was lower compared to the other three groups, Data are presented regarding calcium excretion, phosphate clearance and tubular reabsorption of phosphate for each group. At operation single or multiple adenoma formation was present in 133 patients, whereas diffuse hyperplasia was found in 17 and carcinoma in 2 other patients. 46 of the adenomas were found in an atypical anatomical localisation. This observation is responsible for the many unsuccessful or second explorations of the neck; The weight of the adenomas varied between 0.1 and 23.5 g. The most difficult diagnosis was that of diffuse hyperplasia. The sucess of the surgical intervention was usually established in over 80% of the cases within 24 to 48 hours after the operation with a significant fall of serum calcium. There ist still no definite explanation for the variability of the clinical manifestations of primary hyperparathyroidism. Parathyroid hormone determinations on larger numbers of patients are not yet published. The assumption, that different hormones or peptide fragments are reposible for the different action on bone and kidney is discussed; In our series of 152 patients acute hyperparathyroid crisis occurred eight times. Our findings are compared to the other well documented cases in the literature. Main symptoms were nausea, vomiting, abdominal pain and different states of cerebral dysfunction. Most of the patients had calcium levels over 16 mg/100 ml. Partial renal insufficiency with elevated blood urea and phosphate retention was found in over 50% of the cases. Overall mortality of all cases with acute parathyroid crisis is 52.5%. The pathogenesis of acute hyperparathyroidism and the implications of high calcium levels are discussed. According to our own experience hypercalcenia can be controlled with an intensive therapeutic program and emergency operation for acute parathyroid crisis is no longer necessary.
Supporting Cooperative Work in Virtual Environments (1994)

This paper explores the use of multi-actor virtual reality systems to support communication and cooperation between groups of people. In particular, it introduces a spatial model of interaction which aims to support people in using their natural social communication skills when working together. First, we briefly review some of the social science background which has informed the development of this model. Next, we define the model's main concepts, i.e. aura, awareness, focus, nimbus, adapters and boundaries. We also explore the issues of user embodiment and spatial structure, the latter leading to the concept of Populated Information Terrains. We then show how a few simplifying assumptions results in the notion of awareness states and discuss how these link to the results of previous studies of cooperative work. Following this, we present some early prototypes which realise our concepts within the DIVE distributed virtual reality system. In the first of these, a simple discrete version of the spatial model has been constructed based on the notion of awareness states. The second, Q-PIT, demonstrates an early Populated Information Terrain. Finally, we briefly reflect on the relationship between this work and other CSCW systems based on the metaphor of shared space.
A 16Gb/s 3.7mW/Gb/s 8-tap DFE receiver and baud rate CDR with 30kppm tracking bandwidth (2013)

The circuit presented is a power-efficient implementation of a 16 Gb/s I/O link NRZ receiver in 22 nm CMOS SOI. A CTLE feeds an 8-tap DFE for ISI equalization. The first tap uses digital speculation and the following seven taps are realized with switched-capacitor technique. Timing recovery and control are performed with a Mueller-Müller type-A baud rate CDR. The receiver architecture is half rate and requires only a single phase rotator. In total, six comparators in each even/odd signal path slice recover both data and timing information. The timing information extraction requires four additional comparators per slice in parallel to the two required by the first-tap DFE speculation. The CDR digital section operates at quarter rate and features a low-latency implementation for the timing control loop. At 16 Gb/s, 1 Vppd PRBS31 data transmitted without FFE equalization are recovered error-free (BER <; 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-12</sup> ) across a PCB channel with 34 dB attenuation at 8 GHz. The measured tracking bandwidth is 30 kppm (16 GHz ±480 MHz), and an amplitude of 3 UIPP is tolerated at 1 MHz sinusoidal jitter. The sinusoidal jitter amplitude tolerance measured at 10 Gb/s is 0.4 UIPP at 10 MHz and remains above 0.2 UIPP up to 1 GHz with PRBS31 data recovered error-free (BER<; 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-12</sup> ) across a PCB channel with 27 dB attenuation at 5 GHz. The power efficiency is 3.7 mW/Gb/s, including the full-rate clock receiver.
Reaktionen mit Silylaziden, 7. Über 4‐Isocyanatocarbonsäure‐trimethylsilylester und 4‐Aminocarbonsäure‐<i>N</i>‐carbonsäureanhydride (1975)

Abstract Durch Umsetzung cyclischer 1,3‐Dicarbonsäureanhydride ( 10, 11, 12, 15 ) mit Trimethylsilylazid ( 9 ) wurden verschiedene 4‐Isocyanatocarbonsäure‐trimethylsilylester ( 6a–h, 13, 14, 16, 17 ) erhalten. Durch schonende Hydrolyse dieser Silylester ließen sich die entsprechenden 4‐Isocyanatocarbonsäuren freisetzen, die in allen Fällen der Additionspolymerisation zu den unbeständigen, linearen Oligo(4‐Aminocarbonsäure‐ N ‐carbonsäureanhydriden) unterliegen. Parallel dazu erfolgt in manchen Fällen Cyclisierung zu kristallinen, siebengliedrigen 4‐Aminocarbonsäure‐NCA ( 20—25 ), die aber nicht von allen 4‐Isocyanatocarbonsäuren beobachtet oder isoliert werden konnten. Beim Erhitzen sowie unter basischer Katalyse decarboxylieren sowohl die linearen als auch die cyclischen NCA unter Bildung von Oligoamiden ( 36, 37 ); parallel dazu erfolgt auch Ringverengung zu den entsprechenden fünfgliedrigen Lactamen ( 26–30 ), die insbesondere bei der thermischen Decarboxylierung die Hauptprodukte sind. Hochmolekulare Polyamide wurden in keinem Fall erhalten.
A Concise History of Mathematics. By Dirk J. Struik. Pp. xx + 299, with 47 illustrations. London, 1954: G. Bell & Sons. 14<i>s</i>. net. (1955)

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Multimodal Dialogue Management - State of the art (2006)

This report is about the state of the art in dialogue management. We first introduce an overview of a multimodal dialogue system and its components. Second, four main approaches to dialogue management are described (finite-state and frame-based, information-state based and probabilistic, plan-based, and collaborative agent-based approaches). Finally, the dialogue management in the recent dialogue systems is presented.
Active Risk Estimation (2010)

We address the problem of evaluating the risk of a given model accurately at minimal labeling costs. This problem occurs in situations in which risk estimates cannot be obtained from held-out training data, because the training data are unavailable or do not reflect the desired test distribution. We study active risk estimation processes in which instances are actively selected by a sampling process from a pool of unlabeled test instances and their labels are queried. We derive the sampling distribution that minimizes the estimation error of the active risk estimator when used to select instances from the pool. An analysis of the distribution that governs the estimator leads to confidence intervals. We empirically study conditions under which the active risk estimate is more accurate than a standard risk estimate that draws equally many instances from the test distribution. 1.
Particle Size Measurement by a Powder Film Method (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTParticle Size Measurement by a Powder Film MethodC. Edward Capes and Richard D. ColemanCite this: Ind. Eng. Chem. Fundamen. 1973, 12, 1, 124–126Publication Date (Print):February 1, 1973Publication History Published online1 May 2002Published inissue 1 February 1973https://pubs.acs.org/doi/10.1021/i160045a021https://doi.org/10.1021/i160045a021research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Thermoplastic elastomeric composition based on ground rubber tire (2001)

Abstract Ground rubber tire (GRT) is a particulate vulcanizate consisting mainly of rubber hydrocarbon and fillers. Rubber hydrocarbon of GRT (rGRT) has been used as a partial substitute for EPDM rubber in a dynamically vulcanized EPDM/acrylic‐modified HDPE (A‐HDPE) blend. The blends with higher rubber content show poor processability and physical properties, while the compositions with higher plastic content behave like toughened plastics. However, the 60:40 rubber/plastic blend was found to behave as a thermoplastic elastomer, and it was observed that 50% of EPDM can be replaced by rGRT without deterioration in properties.
Wavelength and polarization insensitive 3 dB cross-coupler power dividers by ion exchange in glass (1990)

We have fabricated fiber-compatible, low-loss, wavelength and polarization insensitive 3 dB 2×2 cross couplers by Ag+-Na+ ion exchange in glass. The couplers were designed using the adiabatic invariance condition for graded-index channel waveguides. An excellent agreement between theory and experiment is demonstrated.
Secretion by <i>Toxoplasma gondii</i> of an antigen that appears to become associated with the parasitophorous vacuole membrane upon invasion of the host cell (1987)

Monoclonal antibodies against Toxoplasma gondii were prepared to characterize antigens of the parasite. Immunoperoxidase staining of parasites fixed with paraformaldehyde and glutaraldehyde (PFAGA) followed by Triton X-100 treatment showed that the antibody of clone I-63 recognized an antigen located in the anterior part of the parasite. When analysed by SDS-PAGE and immunoblotting, the antigen migrated in a 66 x 10(3) Mr region. The parasite antigen diminished greatly in parasites after invasion of host cells, but reappeared around a time when intracellular T. gondii multiplied. Immunodetection on PFAGA-fixed T. gondii-infected cells, whose membranes were permeabilized by freeze-thawing in the presence of 5% glycerol, demonstrated that, immediately after parasite invasion, the I-63 antibody-reactive antigen appeared to become associated with the parasitophorous vacuole (PV) membrane, that had been formed mainly by invagination of the host-cell plasma membrane so as to surround an invading parasite. The antigen remained associated with the PV membrane for some time, but disappeared later when the PV increased in size after the parasites had multiplied several times. These results were strengthened by immunoelectron microscopic observations: the antigen that had been localized at the anterior part of the parasite before invasion appeared in an area of the host cell cytoplasm around the tips of penetrating parasites and, thereafter, extended throughout the surface of the PV membrane when parasites completed invasion. Thus, it appears that the I-63-reactive antigen is secreted by T. gondii upon invasion of the host cell and becomes associated with the PV membrane shortly after invasion.
Dividing a supercoiled DNA molecule into two independent topological domains (2011)

Both prokaryotic and eukaryotic chromosomes are organized into many independent topological domains. These topological domains may be formed through constraining each DNA end from rotating by interacting with nuclear proteins; i.e., DNA-binding proteins. However, so far, evidence to support this hypothesis is still elusive. Here we developed two biochemical methods; i.e., DNA-nicking and DNA-gyrase methods to examine whether certain sequence-specific DNA-binding proteins are capable of separating a supercoiled DNA molecule into distinct topological domains. Our approach is based on the successful construction of a series of plasmid DNA templates that contain many tandem copies of one or two DNA-binding sites in two different locations. With these approaches and atomic force microscopy, we discovered that several sequence-specific DNA-binding proteins; i.e., lac repressor, gal repressor, and λ O protein, are able to divide a supercoiled DNA molecule into two independent topological domains. These topological domains are stable under our experimental conditions. Our results can be explained by a topological barrier model in which nucleoprotein complexes confine DNA supercoils to localized regions. We propose that DNA topological barriers are certain nucleoprotein complexes that contain stable toroidal supercoils assembled from DNA-looping or tightly wrapping DNA around DNA-binding proteins. The DNA topological barrier model may be a general mechanism for certain DNA-binding proteins, such as histone or histone-like proteins, to modulate topology of chromosome DNA in vivo.
FDTD-PLRC Technique for Modeling of Anisotropic-Dispersive Media and Metamaterial Devices (2007)

The goal of this paper is to develop a versatile computational engine based on the finite-difference time-domain (FDTD) technique to comprehensively demonstrate the broadband behaviors of devices designed utilizing anisotropic-dispersive metamaterials. In this regard, the frequency-dependent behavior of dispersive materials is incorporated into the FDTD equations with the use of a piecewise linear recursive convolution (PLRC) approach. The FDTD domain is effectively terminated utilizing convolutional perfectly matched layered (CPML) absorbing walls, which are derived from the complex frequency-shifted (CFS) formulation. The CPML has the advantage that it operates only on the filed intensities and has nothing to do with the and constitutive relationships. The CPML is also highly absorptive to both propagating and evanescent waves. Therefore, it would be of great interest for terminating metamaterials having complex constitutive parameters. The developed method is also capable of characterizing periodic configurations illuminated by normal incident plane waves. The FDTD engine is successfully validated through the analyses of several complex metamaterials. The design and characterization of novel devices such as a patch antenna printed on metasubstrate with anisotropic <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">epsiv</i> (omega) - <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">mu </i> (omega)parameters, an electrically small antenna embedded in negative permittivity resonator, and an anisotropic-dispersive self-biased hexagonal ferrite-coupled line (FCL) circulator are highlighted.
High posterior density ellipsoids of quantum states (2014)

Regions of quantum states generalize the classical notion of error bars. High posterior density (HPD) credible regions are the most powerful of region estimators. However, they are intractably hard to construct in general. This paper reports on a numerical approximation to HPD regions for the purpose of testing a much more computationally and conceptually convenient class of regions: posterior covariance ellipsoids (PCEs). The PCEs are defined via the covariance matrix of the posterior probability distribution of states. Here it is shown that PCEs are near optimal for the example of Pauli measurements on multiple qubits. Moreover, the algorithm is capable of producing accurate PCE regions even when there is uncertainty in the model.
Abscisic acid and indole‐3‐butyric acid regulation of maturation and accumulation of storage proteins in somatic embryos of interior spruce (1990)

The ontogenetic course followed by somatic embryos of interior spruce is highly dependent on the media concentration of abscisic acid (ABA). Little or no organized development occurs in the absence of ABA and as the level of ABA is increased, a range of embryo types is produced. “Shooty embryo” structures predominate in many callus lines at low levels of ABA (1‐10 μM), while 10‐20 μM ABA promotes the formation of bipolar embryos that germinate precociously. When ABA is increased to 30‐40 μM, precocious germination is inhibited and opaque cotyledonary embryos characteristic of their zygotic counterparts are formed which enter a period of quiescence. Only “mature” somatic embryos contain significant amounts of storage proteins and the level to which these proteins accumulate is dependent on the concentration of ABA. Indole‐butyric acid (IBA) included with ABA increases the number of mature embryos. Root elongation, which was used as a measure of embryo quality, was never observed from shooty embryo Structures and was 2‐3 fold higher in mature embryos compared to those that germinated precociously.
Random Forest Algorithm for the Classification of Neuroimaging Data in Alzheimer's Disease: A Systematic Review (2017)

<b>Objective:</b> Machine learning classification has been the most important computational development in the last years to satisfy the primary need of clinicians for automatic early diagnosis and prognosis. Nowadays, Random Forest (RF) algorithm has been successfully applied for reducing high dimensional and multi-source data in many scientific realms. Our aim was to explore the state of the art of the application of RF on single and multi-modal neuroimaging data for the prediction of Alzheimer's disease. <b>Methods:</b> A systematic review following PRISMA guidelines was conducted on this field of study. In particular, we constructed an advanced query using boolean operators as follows: <i>("random forest" OR "random forests") AND neuroimaging AND ("alzheimer's disease" OR alzheimer's OR alzheimer) AND (prediction OR classification)</i>. The query was then searched in four well-known scientific databases: Pubmed, Scopus, Google Scholar and Web of Science. <b>Results:</b> Twelve articles-published between the 2007 and 2017-have been included in this systematic review after a quantitative and qualitative selection. The lesson learnt from these works suggest that when RF was applied on multi-modal data for prediction of Alzheimer's disease (AD) conversion from the Mild Cognitive Impairment (MCI), it produces one of the best accuracies to date. Moreover, the RF has important advantages in terms of robustness to overfitting, ability to handle highly non-linear data, stability in the presence of outliers and opportunity for efficient parallel processing mainly when applied on multi-modality neuroimaging data, such as, MRI morphometric, diffusion tensor imaging, and PET images. <b>Conclusions:</b> We discussed the strengths of RF, considering also possible limitations and by encouraging further studies on the comparisons of this algorithm with other commonly used classification approaches, particularly in the early prediction of the progression from MCI to AD.
Large-scale packet classification on FPGA (2015)

Packet classification is a key network function enabling a variety of network applications, such as network security, Quality of Service (QoS) routing, and other value-added services. Routers perform packet classification based on a predefined rule set. Packet classification faces two challenges: (1) the data rate of the network traffic keeps increasing, and (2) the size of the rule sets are becoming very large. In this paper, we propose an FPGA-based packet classification engine for large rule sets. We present a decomposition-based approach, where each field of the packet header is searched separately. Then we merge the partial search results from all the fields using a merging network. Experimental results show that our design can achieve a throughput of 147 Million Packets Per Second (MPPS), while supporting upto 256K rules on a state-of-the-art FPGA. Compared to the prior works on FPGA or multi-core processors, our design demonstrates significant performance improvements.
Cariostatic effects of monofluorophosphate in solutions and dentifrices in rats. (1989)

The cariostatic effectiveness of dentifrices and solutions containing sodium monofluorophosphate (MFP) was evaluated in rats. In one study using 36 CARA rats, the caries inhibiting effects of sodium fluoride and MFP solutions, at equivalent soluble fluoride concentrations (750 ppm F), were compared. Both MFP and sodium fluoride significantly (p less than 0.01) reduced smooth surface caries by 78% to 81%, respectively. No significant differences between the two treatment groups were observed. In a second study, 5 dentifrices formulated with dicalcium phosphate dihydrate (DCPD) abrasive and different amounts of MFP (0, 250, 500, 750, and 1000 ppm F) were tested for cariostatic effects in CARA rats. Compared to the control groups, the MFP/DCPD dentifrices significantly (p less than 0.01) reduced smooth surface caries incidence by 66%, 81%, 76% and 85% at the 250, 500, 750, and 1000 ppm F concentrations, respectively. In each of the studies, both enamel fluoride content and molar surface solubility were measured. A third study assessed the compatibility of MFP with different abrasives and the effect of dentifrice composition on the release of MFP from a dentifrice slurry to a saliva phase. No differences in MFP release were observed for two different silica-based formulations which differed with respect to thickener, humectants and other ingredients.