gebhart/patrepeval huggingface dataset:
Craniofacial Superimposition in Forensic Identification using Genetic Algorithms (2007)

Craniofacial superimposition is a process that aims to identify a person by overlaying a photograph and a model of the skull. This process is usually carried out manually by forensic anthropologists; thus being very time consuming and presenting several difficulties in finding a good fit between the 3D model of the skull and the 2D photo of the face. In this paper we present a fast and automatic procedure to tackle the superimposition problem. The proposed method is based on real-coded genetic algorithms. Synthetic data are used to validate the method. Results on a real case from our Physical Anthropology lab of the University of Granada are also presented.
N-[(Tetrahydrofuryl)alkyl] and N-(alkoxyalkyl) derivatives of (-)-normetazocine, compounds with differentiated opioid action profiles (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN-[(Tetrahydrofuryl)alkyl] and N-(alkoxyalkyl) derivatives of (-)-normetazocine, compounds with differentiated opioid action profilesHerbert Merz and Klaus StockhausCite this: J. Med. Chem. 1979, 22, 12, 1475–1483Publication Date (Print):December 1, 1979Publication History Published online1 May 2002Published inissue 1 December 1979https://pubs.acs.org/doi/10.1021/jm00198a009https://doi.org/10.1021/jm00198a009research-articleACS PublicationsRequest reuse permissionsArticle Views178Altmetric-Citations58LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: Inorganic Fibers ‐ A Literature Review (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Image quality and dose optimization using novel x-ray source filters tailored to patient size (2005)

The expanding set of CT clinical applications demands increased attention to obtaining the maximum image quality at the lowest possible dose. Pre-patient beam shaping filters provide an effective means to improve dose utilization. In this paper we develop and apply characterization methods that lead to a set of filters appropriately matched to the patient. We developed computer models to estimate image noise and a patient size adjusted CTDI dose. The noise model is based on polychromatic X-ray calculations. The dose model is empirically derived by fitting CTDI style dose measurements for a demographically representative set of phantom sizes and shapes with various beam shaping filters. The models were validated and used to determine the optimum IQ vs dose for a range of patient sizes. The models clearly show that an optimum beam shaping filter exists as a function of object diameter. Based on noise and dose alone, overall dose efficiency advantages of 50% were obtained by matching the filter shape to the size of the object. A set of patient matching filters are used in the GE LightSpeed VCT and Pro<sup>32</sup> to provide a practical solution for optimum image quality at the lowest possible dose over the range of patient sizes and clinical applications. Moreover, these filters mark the beginning of personalized medicine where CT scanner image quality and radiation dose utilization is truly individualized and optimized to the patient being scanned.
Unique phospholipid metabolism in mouse heart in response to dietary docosahexaenoic or α‐linolenic acids (2001)

Diet and fatty acid metabolism interact in yet unknown ways to modulate membrane fatty acid composition and certain cellular functions. For example, dietary precursors or metabolic products of n-3 fatty acid metabolism differ in their ability to modify specific membrane components. In the present study, the effect of dietary 22:6n-3 or its metabolic precursor, 18:3n-3, on the selective accumulation of 22:6n-3 by heart was investigated. The mass and fatty acid compositions of individual phospholipids (PL) in heart and liver were quantified in mice fed either 22:6n-3 (from crocodile oil) or 18:3n-3 (from soybean oil) for 13 wk. This study was conducted to determine if the selective accumulation of 22:6n-3 in heart was due to the incorporation of 22:6n-3 into cardiolipin (CL), a PL most prevalent in heart and known to accumulate 22:6n-3. Although heart was significantly enriched with 22:6n-3 relative to liver, the accumulation of 22:6n-3 by CL in heart could not quantitatively account for this difference. CL from heart did accumulate 22:6n-3, but only in mice fed preformed 22:6n-3. Diets rich in non-22:6n-3 fatty acids result in a fatty acid composition of phosphatidylcholine (PC) in heart that is unusually enriched with 22:6n-3. In this study, the mass of PC in heart was positively correlated with the enrichment of 22:6n-3 into PC. The increased mass of PC was coincident with a decrease in the mass of phosphatidylethanolamine, suggesting that 22:6n-3 induced PC synthesis by increasing phosphatidylethanolamine-N-methyltransferase activity in the heart.
Advancements in Technology and Process Approach Reduce Cost and Increase Performance of CO2 Flow Monitoring and Remediation (2010)

Abstract A novel, cost-saving approach combining rapidly-acquired CO2 flow measurements and early-alteration improves CO2 placement, leak detection, and remediation in CO2 enhanced oil recovery (EOR) and carbon capture and storage (CCS) projects. The approach is based on field-proven technologies for monitoring CO2 flows and for controlling flows within reservoirs or remediating flows outside of reservoirs. The new low-cost monitoring technology employs reservoir flow induced micro-deformation measurements by three basic technologies—satellite-based interferometric synthetic aperture radar (InSAR), surface and downhole tiltmeters, and differential global positioning systems (GPS). These methods acquire microdeformation data in near-real-time (NRT). This data supports NRT geomechanical inversion analysis that provides 3-D reservoir flow images. Real-time temperature and pressure data from wells instrumented with sensors connected to fiberoptic cables may also be used to better characterize some CO2 flows. The new lost-cost flow control and remediation technology is derived from improvements in flowpath sealants and placement methods that can alter flows both inside and outside of reservoirs. This monitoring technology has evolved from similar methods proven in other types of secondary and tertiary recovery projects, and more recently in CCS projects, to identify reservoir flows and pinpoint abnormal ones. An example of normal CO2 flow results is presented to show how operators can calibrate flow-prediction software models and make fast decisions to apply flow enhancing methods. These methods improve CO2 sweep efficiency, increase oil production, and better utilize the reservoirs’ CO2 storage capacity. Another example shows the early identification of an abnormal flowpath location that enables timely selection of sealing methods and materials that eliminate unwanted flows from reservoirs with negligible CO2 losses. The CO2 flow control and remediation technology’s history of field-proven success is described along with recent developments that have improved both material and placement performance. Generic case histories of conventional vs. the proposed new approach are compared to show how the combination of rapidly-deployed, CO2 flow-alteration and monitoring technologies creates synergies that can improve the performance of CO2 EOR and CCS projects while reducing operating costs.
Colored shading nets impede insect invasion and decrease the incidences of insect‐transmitted viral diseases in vegetable crops (2012)

Abstract Black shading nets are commonly used to protect agricultural crops from excessive solar radiation and wind, and for water saving. Recent studies have demonstrated that when black nets were replaced by either red, yellow, or pearl nets ( C hromati N ets ™ ) of equivalent shading capacity, it increased the fruit yield and improved the quality of bell peppers ( C apsicum annuum L .) and tomatoes ( S olanum lycopersicum L .) (both S olanaceae). We studied the effects of these colored shading nets on the infestation by aphids [ M yzus persicae ( S ulzer) and A phis gossypii Glover (both H emiptera: A phididae)] and whiteflies [ B emisia tabaci ( G ennadius) ( H emiptera: A leyrodidae)], and the incidence of the viral diseases transmitted by these insects, for five consecutive years (2006–2010). These studies were conducted in the semi‐arid B esor region in southern Israel. The plants were grown in ‘walk‐in’ tunnels that were covered by several nets of 35% shading capacity in the range of photosynthetically active radiation. Although the shading nets permit free passage of these pests, the infestation levels of aphids and whiteflies in tunnels covered by either the yellow or pearl nets were consistently 2–3× lower than in tunnels covered by the black or red nets. In accordance with the pest results, when the incidences of C ucumber mosaic virus in pepper grown under the black or red nets ranged between 35 and 89%, they were 2–10× lower under the yellow or pearl nets. Similarly, when the incidences of necrotic P otato virus Y in tomato grown under black or red nets ranged between 42 and 50%, they were 2–3× lower under the yellow or pearl nets. Also, when the incidences of T omato yellow leaf curl virus in tomato grown under the black or red nets ranged between 15 and 50%, but they were 2–4× lower under the yellow or pearl nets. Putative mechanisms of crop protection achieved by the yellow and pearl nets are discussed.
HSV-1 quantitation from rabbit neural tissues after epinephrine-induced reactivation. (1985)

Epinephrine iontophoresis into the eye can induce ocular herpes simplex virus type-1 (HSV-1) shedding with a high frequency from latently infected rabbits. The present study was designed to qualify and quantify infectious HSV-1 from neural tissues of latently infected rabbits after ocular epinephrine iontophoresis. Epinephrine iontophoresis was performed daily for 3 consecutive days on selected days during 220-227 days postinoculation. The induced ocular shedding was detected in the tear film with a frequency of 83% (10/12) within 72 hr after the initial iontophoresis. The rabbits were killed 24 hr after the last iontophoretic treatment, and the corneas and neural tissues were homogenized immediately. The cell-free supernatants were inoculated on primary rabbit kidney cell monolayers for qualitative assays of infectious virus and later titrated on CV-1 monolayers. The frequencies of the recovery of infectious HSV-1 from the cell-free homogenates were 0% of the corneas (0/12), 83% (10/12) from the superior cervical ganglion (SCG), 100% (12/12) from the trigeminal ganglion (TG), 42% (5/12) from the ophthalmic branch of the trigeminal nerve (TN), 8% (1/12) from the root entry zone of the trigeminal nerve into the brain-stem (REZ), and 0% (0/12) from the cerebellum. The authors conclude that epinephrine iontophoresis can reactivate the latent HSV-1 in neural tissues and infectious virus can be quantified from the cell-free homogenates. To the best of our knowledge, this is the first report to quantify HSV-1 with a high frequency from neural tissues following induced reactivation.
Heat Transfer Characteristics of Impinging Two-Dimensional Air Jets (1966)

Local as well as average heat transfer coefficients between an isothermal flat plate and impinging two-dimensional jets were measured for both single jets and arrays of jets. For a large and technologically important range of variables the results have been correlated in relatively simple terms, and their application to design is briefly considered.
Pentoxifylline in vivo down-regulates the release of IL-1 beta, IL-6, IL-8 and tumour necrosis factor-alpha by human peripheral blood mononuclear cells. (1994)

Pentoxifylline (PTX) is a methylxanthine compound known to inhibit the production of tumour necrosis factor-alpha (TNF-alpha), which is an important inflammatory mediator. There is also recent evidence that PTX may influence other inflammatory cytokines, such as interleukin-1 (IL-1) and IL-6. Due to the therapeutic implications, the present study addressed the in vivo effects of PTX on the release of TNF-alpha, IL-1 beta, IL-6 and IL-8 by human peripheral blood mononuclear cells (PBMC). When PBMC were obtained from healthy volunteers ingesting 5 x 400 mg PTX orally for 2 days, the ability of PBMC cultured for 24 hr to release TNF-alpha was significantly reduced, while secretion of IL-1 beta, IL-6 and IL-8 was not affected. However, when PBMC were obtained from the same individuals 5 days after PTX had been stopped, the release of all four cytokines was significantly suppressed. This effect appeared to be exerted at the transcriptional level, since Northern blot analysis revealed reduced cytokine transcripts. In order to gain more insight into the effect of PTX on cytokine release, PBMC were obtained from normal volunteers, either stimulated with lipopolysaccharide (LPS) or left unstimulated, and subsequently incubated in vitro with PTX for 48 hr. Under these conditions, only TNF-alpha was found to be reduced by PTX, while IL-1 beta and IL-8 were not affected, IL-6 was even enhanced. However, when PBMC were incubated with PTX for 24 hr, PTX removed thereafter by medium change and cells further cultured, the production not only of TNF-alpha but also of IL-1 beta, IL-6 and IL-8 was reduced, demonstrating that PTX exerts diverse (inhibitory) effects on cytokine release by PBMC.
Glucose-6-phosphate dehydrogenase from <i>Leuconostoc mesenteroides</i> (1989)

Conference Article| April 01 1989 Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides H. RICHARD LEVY H. RICHARD LEVY 1Department of Biology, Syracuse University, Syracuse, NY 13244-1220, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1989) 17 (2): 313–315. https://doi.org/10.1042/bst0170313 Article history Received: August 11 1988 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation H. RICHARD LEVY; Glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Biochem Soc Trans 1 April 1989; 17 (2): 313–315. doi: https://doi.org/10.1042/bst0170313 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: G6PD, glucose-6-phosphate dehydrogenase This content is only available as a PDF. © 1989 Biochemical Society1989 Article PDF first page preview Close Modal You do not currently have access to this content.
Immature Human Megakaryocytes Produce Nuclear-Associated Acetylcholinesterase (1997)

Acetylcholinesterase (AChE) is expressed in murine megakaryocytes (MK), where its antisense inhibition suppresses differentiation, yet was never detected in human MK. Here, we report that AChE is produced in normal human bone marrow MK and in cell lines derived thereof. Reverse transcriptase-polymerase chain reaction (RT-PCR) amplification showed two ACHEmRNA forms in human megakaryoblastic DAMI cells. In situ hybridization demonstrated ACHEmRNA surrounding the nucleus of small DAMI cells and the nuclear lobes of large, polyploid cells. Differentiation induction with phorbol ester and exposure to recombinant human thrombopoietin suppressed both ACHEmRNA and AChE activity. The residual AChE in mature differentiated cells acquired higher stability and detergent-sensitivity as compared with AChE in small proliferating cells. AChE activity was primarily associated with nuclei of both DAMI cells and small (10 microm) primary proliferating human bone marrow MK identified with GPIIb/IIIa antibodies. This activity was significantly reduced in medium size MK (10 to 25 microm) and was almost undetectable in large MK (>25 microm), yet was twofold more abundant in some large MK from idiopathic thrombocytopenia purpura (ITP) patients with accelerated MK maturation. The loss of AChE activity at the transition from proliferating to differentiating MK highlights species-specific differences in its expression, suggesting a distinct role for AChE in human MK development.
Long-Term In-Reactor Corrosion and Hydriding of Zircaloy-2 Tubing (1982)

Three original Zircaloy-2 clad blanket fuel bundles from the pressurized-water reactor (PWR) at the Shippingport Atomic Power Station were discharged after continuous exposure during Cores 1 and 2. Detailed visual examination of these components after ∼6300 calendar days of operation (51 140 effective full power hours) revealed only the anticipated uniform light gray (posttransition) corrosion products with no evidence of unexpected corrosion deterioration, fuel rod warpage, or other damage. All corrosion films were found to be tightly adherent to the underlying cladding. An extensive destructive examination of a selected fuel rod from each of three fuel bundles produced, as expected, significantly greater end-of-life rod average oxide film thicknesses when compared with corresponding values calculated from the time-temperature history of each component, employing a set of empirical equations generated from the out-of-pile (autoclave) testing of Zircaloy coupons. It is shown that the pretransition region and the time to transition are in adequate agreement with the empirical equations generated from the ex-reactor data but that there is a significant acceleration of the posttransition corrosion rate due to the irradiation exposure. Post-transition corrosion rate data were used to develop an empirical expression of the form R′=A(φ)n·R where R′ is the in-reactor posttransition corrosion rate for Zircaloy-2 tubing, A and n are experimentally determined constants, φ is the posttransition fast flux exposure, and R is the posttransition temperature-dependent corrosion rate generated from exreactor (autoclave) testing. The Multipurpose Extended Life Blanket Assembly cladding in the mid-sections of the rods (α microstructure) was found to have corroded at a rate that is approximately 25 percent greater than the corresponding welded end cap regions (β-quenched struture). It has been observed that the total hydrogen content of the cladding was less than that calculated from the ex-reactor expressions, using the measured oxide film thickness. It has also been found that the hydrogen pickup per unit weight gain is two to three times greater in the late posttransition period than that observed in the early posttransition region, possibly casting doubt on the validity of the application of the ex-reactor hydrogen pickup expression (that is, a constant ΔH/Δ0 ratio for the entire posttransition region) to in-reactor exposures.
The fbpABC locus of Neisseria gonorrhoeae functions in the periplasm-to-cytosol transport of iron (1996)

We have determined that the DNA sequence downstream of the well-characterized gonococcal fbp gene contains two open reading frames: one designated fbpB, which encodes a protein proposed to function as a cytoplasmic permease, and one designated fbpC, which encodes a protein proposed to function as a nucleotide-binding protein. The fpbABC operon composes an iron transport system that is homologous to the sfu and hit operons previously reported for Serratia marcescens and Haemophilus influenzae, respectively, and displays elements characteristic of ATP binding cassette transporters. The fpbABC operon differs from these loci in that it is lethal when overexpressed in Escherichia coli.
Test of a fiber Bragg grating sensor network for commercial aircraft structures (2003)

The field test reported on in this paper has shown the great potential of fiber-optic Bragg gating sensors. They are suitable for load monitoring of aviation structures under real-world conditions. The results obtained with the Bragg gratings show excellent consistency with the strain gage results. This indicates that both the sensor installation technique of gluing the sensors to the surface and the sensor interrogation technique using a tunable laser-based system, both of which were studied in the field test, are well-suited for these measurements. In addition, the fiber-optic sensor network has several advantages: it is immune to electromagnetic interference and has high multiplexing capability, for hundreds of these sensors can be aligned along a single optical fiber, if desired. This significantly reduces the effort needed for wiring and also leads to a considerable decrease in weight compared to standard electrical sensor networks.
Site and Strain-Specific Variation in Gut Microbiota Profiles and Metabolism in Experimental Mice (2010)

Strain-specific data were suggestive of genetic determination of the composition and activities of intestinal symbiotic consortia. However, relocation studies and uterine implantation demonstrated the dominance of environmental influences on the GTM. This was manifested in large variations between isogenic adult mice reared in different research institutions.