gebhart/patrepeval huggingface dataset:
Effects of stimulation mode on threshold and loudness growth in multielectrode cochlear implants (1999)

The effect of increasing the separation between the two members of a stimulating electrode pair was studied in four users of the Nucleus-22 cochlear implant. Two experiments were performed. In experiment 1, detection threshold for a 200-ms, 500-pulses/s biphasic pulse train was measured as the spatial separation between the active and return electrodes was increased. In experiment 2, loudness-growth functions were measured as the electrode separation was increased. The results of experiment 1 indicate that (a) threshold decreases monotonically toward an asymptote (monopolar threshold) as the electrode separation is increased and (b) the threshold versus electrode separation function is similar across subjects and electrode location. The results of experiment 2 indicate that loudness L is related to the current amplitude I by a simple exponential function: L = e beta I, where beta, the exponent of the loudness function, is, to a first approximation, linearly related to the separation between the electrodes of the stimulating pair. Thus, dynamic range and the shape of loudness growth can be directly linked to the spatial separation between active and return electrodes.
DRIP: A framework for purifying trojaned kernel drivers (2013)

Kernel drivers are usually provided in the form of loadable kernel extensions, which can be loaded/unloaded dynamically at runtime and execute with the same privilege as the core operating system kernel. The unrestricted security access from the drivers to the kernel is nevertheless a double-edged sword that makes them susceptible targets of trojan attacks. Given a benign driver, it is now easy to implant malicious logic with existing hacking tools. Once implanted, such malicious logic is difficult to detect. In this paper we propose DRIP, a framework for detecting and eliminating malicious logic embedded in a kernel driver through iteratively eliminating unnecessary kernel API invocations from the driver. When provided with the binary of a trojaned driver, DRIP generates a purified driver with benign functionalities preserved and malicious ones eliminated. Our evaluation shows that DRIP successfully eliminates malicious effects of trojaned drivers in the system, with the purified drivers maintaining or even improving their performance over the trojaned drivers.
Simultaneous registration of multiple range views for use in reverse engineering (1996)

When reverse engineering a CAD model, it is necessary to integrate information from several views of an object into a common reference frame. Given a rough initial alignment, further pose refinement here uses an improved version of the interactive closes point algorithm. Incremental adjustments are computed simultaneously for all data sets, resulting in a more globally optimal set of transformations. Also, thresholds for removing outlier correspondences are not needed, as the merging data sets are considered as a whole. Motion updates are computed through force-based optimization, using implied springs between data sets. Experiments indicate that even for very rough initial positionings, registration accuracy approaches 25% of the interpoint sampling resolution of the images.
Surface-enhanced Raman scattering detection of chemical and biological agent simulants (2005)

Surface-enhanced Raman scattering spectra of chemical and biological agent simulants, such as dimethyl methylphonate, pinacolyl methylphosphonate, diethyl phosphoramidate, 2-chloroethyl ethylsulfide, bacillus globigii, erwinia herbicola, and bacillus thuringiensis were obtained from silver-oxide film-deposited substrates. Thin AgO films ranging in thickness from 50 to 250 nm were produced by chemical bath deposition onto glass slides. Further Raman intensity enhancements were noticed in UV irradiated surfaces due to photo-induced Ag nanocluster formation, which may provide a possible route to producing highly useful plasmonic sensors for the detection of chemical and biological agents upon visible-light illumination.
Threading plasmonic nanoparticle strings with light (2014)

Nanomaterials find increasing application in communications, renewable energies, electronics and sensing. Because of its unsurpassed speed and highly tuneable interaction with matter, using light to guide the self-assembly of nanomaterials can open up novel technological frontiers. However, large-scale light-induced assembly remains challenging. Here we demonstrate an efficient route to nano-assembly through plasmon-induced laser threading of gold nanoparticle strings, producing conducting threads 12±2 nm wide. This precision is achieved because the nanoparticles are first chemically assembled into chains with rigidly controlled separations of 0.9 nm primed for re-sculpting. Laser-induced threading occurs on a large scale in water, tracked via a new optical resonance in the near-infrared corresponding to a hybrid chain/rod-like charge transfer plasmon. The nano-thread width depends on the chain mode resonances, the nanoparticle size, the chain length and the peak laser power, enabling nanometre-scale tuning of the optical and conducting properties of such nanomaterials.
Ti6Ta4Sn Alloy and Subsequent Scaffolding for Bone Tissue Engineering (2009)

Porous titanium (Ti) and titanium alloys are promising scaffold biomaterials for bone tissue engineering, because they have the potential to provide new bone tissue ingrowth abilities and low elastic modulus to match that of natural bone. In the present study, a new highly porous Ti6Ta4Sn alloy scaffold with the addition of biocompatible alloying elements (tantalum (Ta) and tin (Sn)) was prepared using a space-holder sintering method. The strength of the Ti6Ta4Sn scaffold with a porosity of 75% was found to be significantly higher than that of a pure Ti scaffold with the same porosity. The elastic modulus of the porous alloy can be customized to match that of human bone by adjusting its porosity. In addition, the porous Ti6Ta4Sn alloy exhibited an interconnected porous structure, which enabled the ingrowth of new bone tissues. Cell culture results revealed that human SaOS(2) osteoblast-like cells grew and spread well on the surfaces of the solid alloy, and throughout the porous scaffold. The surface roughness of the alloy showed a significant effect on the cell behavior, and the optimum surface roughness range for the adhesion of the SaOS(2) cell on the alloy was 0.15 to 0.35 mum. The present study illustrated the feasibility of using the porous Ti6Ta4Sn alloy scaffold as an orthopedic implant material with a special emphasis on its excellent biomechanical properties and in vitro biocompatibility with a high preference by osteoblast-like cells.
CYP1A1 T<sup>3801</sup> C polymorphism and lung cancer: A pooled analysis of 2,451 cases and 3,358 controls (2003)

CYP1A1 is involved in the metabolism of benzopyrene, a suspected lung carcinogen; it is therefore conceivable that genetically determined variations in its activity modify individual susceptibility to lung cancer. The role of the CYP1A1 MspI polymorphism in lung cancer has been widely studied but has not been fully clarified. We have included 2,451 cases and 3,358 controls in a pooled analysis of 22 case-control studies on CYP1A1 and lung cancer risk. We found a clear association between the CYP1A1 homozygous MspI restriction fragment length polymorphism (RFLP) and lung cancer risk in Caucasians (age- and gender-adjusted odds ratio = 2.36; 95% confidence interval 1.16-4.81); other associations were weaker or not statistically significant. The association with the homozygous variant was equally strong for squamous cell carcinomas and adenocarcinomas among Caucasians. We analyzed the risk by duration of smoking: for Caucasian subjects with the MspI RFLP combined variants (homozygotes plus heterozygotes), the increase in the risk of lung cancer was steeper than among the individuals with the homozygous reference allele. Our analysis suggests that Caucasians with homozygous variant CYP1A1 polymorphism have a higher risk of lung cancer. The data were more consistent among Caucasians, with a strong association between the homozygous variant in both squamous cell carcinomas and adenocarcinomas, and a stronger association in men than in women. The analyses were more inconsistent and failed to reach statistical significance in Asians. This observation might be due to design specificities or unknown effect modifiers in the Asian studies.
Technological advancement in the era of COVID-19 (2021)

Regional and local governments worldwide are working tirelessly toward effective ways of addressing the COVID-19 crisis. During this time, the government has had to ensure that they provide full usage of technological means to confront the pandemic and discourse a wide range of COVID-19 related problems. Herein, this article will discuss the application of technical means and the advancement of technology in different sectors as a consequence of the COVID-19 crisis. Further, it highlights how government and health organizations have introduced new policies intending to try to curb the spread of the coronavirus. These new policies, such as lockdowns and social distancing measures, have resulted in technological advancement and new means of interaction with government, businesses, and citizens. Such changes include increased online shopping, as well as robotic delivery systems, the introduction of digital as well as contactless payment systems, remote working, the role of technology in distance learning, Telehealth, 3D Printing, and online entertainment. These technological advancements have been embraced all the way during this pandemic by a few countries around the world, with its limitation in some underdeveloped and developing countries.
Conformation of the N-Terminal Segment of a Monocysteine Mutant of Troponin I from Cardiac Muscle (1997)

A monocysteine mutant of cardiac muscle troponin I, cTnI(S5C/C81I/C98S), was generated from a mouse cTnI cDNA clone and expressed in a bacterial system. Cys-5 was modified with the fluorescent sulfhydryl reagent IAANS to probe the conformation of the N-terminal extension of the mutant and the mutant complexed with cardiac muscle troponin C. Our emphasis was on the effect of phosphorylation of Ser-23 and Ser-24 by protein kinase A on the conformation of the N-terminal segment. Phosphorylation resulted in an 8-nm red-shift of the emission spectrum of the attached IAANS probe and a reduction of its quantum yield by a factor of 4-5. The intensity decay of nonphosphorylated IAANS-labeled mutant was complex and had to be described by a sum of three exponential terms, with lifetimes in the range 0.1-5 ns. A fourth component in the range 7-9 ns was required to describe the intensity decay of the phosphorylated mutant. Phosphorylation also reduced the weighted mean lifetime, consistent with the changes observed in the steady-state fluorescence parameters and a 33% decrease in the global rotational correlation time calculated from anisotropy decay data. This change in correlation time suggested a decrease in the axial ratio of the protein. The fluorescence changes of the labeled mutant induced by phosphorylation were carried over to its complex with troponin C. The Stern-Volmer plots of acrylamide quenching of the steady-state fluorescence were essentially linear for nonphosphorylated mutant but displayed pronounced concave downward curvatures for the phosphorylated protein under all conditions studied. The present results are interpreted in terms of a more compact hydrodynamic shape of the phosphorylated cTnI mutant and are consistent with a folded conformation of the N-terminal extension induced by phosphorylation of the two serines. These conformational changes may play a role in the modulation of cardiac muscle contractility by troponin I phosphorylation.
Reduced Insulinotropic Effect of Gastric Inhibitory Polypeptide in First-Degree Relatives of Patients With Type 2 Diabetes (2001)

In patients with type 2 diabetes, gastric inhibitory polypeptide (GIP) has lost much of its insulinotropic activity. Whether this is similar in first-degree relatives of patients with type 2 diabetes is unknown. A total of 21 first-degree relatives, 10 patients with type 2 diabetes, and 10 control subjects (normal oral glucose tolerance) were examined. During a hyperglycemic "clamp" (140 mg/dl for 120 min), synthetic human GIP (2 pmol. kg(-1). min(-1)) was infused intravenously (30-90 min). With exogenous GIP, patients with type 2 diabetes responded with a lower increment (Delta) in insulin (P = 0.0003) and C-peptide concentrations (P < 0.0001) than control subjects. The GIP effects in first-degree relatives were diminished compared with control subjects (Delta insulin: P = 0.04; Delta C-peptide: P = 0.016) but significantly higher than in patients with type 2 diabetes (P < or = 0.05). The responses over the time course were below the 95% CI derived from control subjects in 7 (insulin) and 11 (C-peptide) of 21 first-degree relatives of patients with type 2 diabetes. In conclusion, a reduced insulinotropic activity of GIP is typical for a substantial subgroup of normoglycemic first-degree relatives of patients with type 2 diabetes, pointing to an early, possibly genetic defect.
High sulfur loading lithium–sulfur batteries based on a upper current collector electrode with lithium-ion conductive polymers (2016)

We report an effective double current collector electrode.
“Where is My Parcel?” Fast and Efficient Classifiers to Detect User Intent in Natural Language (2019)

We study the performance of customer intent classifiers designed to predict the most popular intent received through ASOS.com Customer Care Department, namely “Where is my order?”. These queries are characterised by the use of colloquialism, label noise and short message length. We conduct extensive experiments with twowell established classification models: logistic regression via n-grams to account for sequences in the dataand recurrent neural networks that perform the extraction of these sequential patterns automatically. Maintaining the embedding layer fixed to GloVe coordinates, a Mann-Whitney U test indicated that the F1 score on aheld out set of messages was lower for recurrent neural network classifiers than for linear n-grams classifiers (M1=0.828, M2=0.815; U=1,196, P=1.46e-20), unless all layers were jointly trained with all other network parameters (M1=0.831, M2=0.828, U=4,280, P=8.24e-4). This plain neural network produced top performance on a denoised set of labels (0.887 F1) matching with Human annotators (0.889 F1) and superior to linear classifiers (0.865 F1). Calibrating these models to achieveprecision levels above Human performance (0.93 Precision), our results indicate a small difference in Recall of 0.05 for the plain neural networks (training under 1hr), and 0.07 for the linear n-grams (training under 10min), revealing the latter as a judicious choice of model architecture in modern AI production systems.
Portal Hypertension and Gastrointestinal Bleeding (2008)

Variceal bleeding is one of the most serious complications of portal hypertension. The driving force for the development of varices is an increase in portal pressure. As portal hypertension progresses, varices dilate until they finally rupture and bleed. This sequence of events might be prevented by achieving a sufficient decrease in portal pressure or by acting locally at the varices with endoscopic treatments. This article reviews the rationale for the management of portal hypertension and the current recommendations for the prevention and treatment of variceal bleeding.
Low-threshold CW operation of an erbium-doped fibre laser pumped at 807 nm wavelength (1987)

We report an erbium-doped fibre laser operating CW at a wavelength of 1555nm pumped at a wavelength of 807 nm, with a threshold launched pump power of 2.5 mW. This level corresponds to only 1 mW of pump power absorbed.
Exploiting join cardinality for faster hash joins (2009)

Hash joins combine massive relations in data warehouses, decision support systems, and scientific data stores. Faster hash join performance significantly improves query throughput, response time, and overall system performance. In this work, we demonstrate how using join cardinality improves hash join performance. The key contribution is the development of an algorithm to determine join cardinality in an arbitrary query plan. We implemented early hash join and the join cardinality algorithm in PostgreSQL. Experimental results demonstrate that early hash join has an immediate response time that is an order of magnitude faster than the existing hybrid hash join implementation. One-to-one joins execute up to 50% faster and perform significantly fewer I/Os, and one-to-many joins have similar or better performance over all memory sizes.
Effects of Calcium, Magnesium, and Phosphate on Glyphosate Absorption by Cultured Plant Cells (1991)

Effects of several inorganic ions on short-term glyphosate absorption by cultured plant cells were determined by measuring the glyphosate content of cells exposed to inorganic salts in a 0.01-mM glyphosate solution buffered at pH 5.7. Within 10 min, glyphosate absorption by potato and velvetleaf cells was stimulated about equally by 1.5 mM CaCl 2 or 1.5 mM MgCl 2 but was not affected by 1.5 mM KCl. Glyphosate absorption by both species increased linearly with log 10 CaCl 2 concentration; for velvetleaf cells, the response was greatest for CaCl 2 concentrations greater than 0.2 mM. Over time of absorption, glyphosate concentration within velvetleaf cells approached an asymptote. Addition of 0.1 mM KH 2 PO 4 inhibited glyphosate absorption by potato cells in the presence or absence of Ca 2+ and Mg 2+ salts; all other K + salts tested had no effect. Glyphosate absorption by potato, velvetleaf, soybean, corn, and rice cells was stimulated by 5.0 mM CaCl 2 but was inhibited by 0.1 mM KH 2 PO 4 in the presence of 0.05 or 5.0 mM CaCl 2 .
A real-time approach for heart rate monitoring using a Hilbert transform in seismocardiograms (2016)

Heart rate monitoring helps in assessing the functionality and condition of the cardiovascular system. We present a new real-time applicable approach for estimating beat-to-beat time intervals and heart rate in seismocardiograms acquired from a tri-axial microelectromechanical accelerometer. Seismocardiography (SCG) is a non-invasive method for heart monitoring which measures the mechanical activity of the heart. Measuring true beat-to-beat time intervals from SCG could be used for monitoring of the heart rhythm, for heart rate variability analysis and for many other clinical applications. In this paper we present the Hilbert adaptive beat identification technique for the detection of heartbeat timings and inter-beat time intervals in SCG from healthy volunteers in three different positions, i.e. supine, left and right recumbent. Our method is electrocardiogram (ECG) independent, as it does not require any ECG fiducial points to estimate the beat-to-beat intervals. The performance of the algorithm was tested against standard ECG measurements. The average true positive rate, positive prediction value and detection error rate for the different positions were, respectively, supine (95.8%, 96.0% and ≃0.6%), left (99.3%, 98.8% and ≃0.001%) and right (99.53%, 99.3% and ≃0.01%). High correlation and agreement was observed between SCG and ECG inter-beat intervals (r > 0.99) for all positions, which highlights the capability of the algorithm for SCG heart monitoring from different positions. Additionally, we demonstrate the applicability of the proposed method in smartphone based SCG. In conclusion, the proposed algorithm can be used for real-time continuous unobtrusive cardiac monitoring, smartphone cardiography, and in wearable devices aimed at health and well-being applications.
A QVGA-range image sensor based on buried-channel demodulator pixels in 0.18&#x03BC;m CMOS with extended dynamic range (2012)

3D vision systems have recently started to penetrate the consumer market, mainly in the entertainment segment, with products based on pattern-projection techniques. Although this technology has shown remarkable performance in terms of cost, measurement accuracy and power consumption, there is also an increasing interest towards alternative techniques, such as stereo vision and Time-of-Flight (ToF), in order to further improve the range camera characteristics. After a decade from the demonstration of the first ToF range imagers with reasonably good performance results [1], this technology has started to attract the attention of large companies, because of the potential consumer applications in security, gaming and ambient assisted living.
Intramolecular hydrogen transfer in mass spectra. III. Rearrangements involving the loss of small neutral molecules (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntramolecular hydrogen transfer in mass spectra. III. Rearrangements involving the loss of small neutral moleculesDavid G. I. Kingston, Brice W. Hobrock, Maurice M. Bursey, and Joan T. BurseyCite this: Chem. Rev. 1975, 75, 6, 693–730Publication Date (Print):December 1, 1975Publication History Published online1 May 2002Published inissue 1 December 1975https://pubs.acs.org/doi/10.1021/cr60298a002https://doi.org/10.1021/cr60298a002research-articleACS PublicationsRequest reuse permissionsArticle Views671Altmetric-Citations64LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Noise Model Transfer: Novel Approach to Robustness Against Nonstationary Noise (2013)

This paper proposes an approach, called noise model transfer (NMT), for estimating the rapidly changing parameter values of a feature-domain noise model, which can be used to enhance feature vectors corrupted by highly nonstationary noise. Unlike conventional methods, the proposed approach can exploit both observed feature vectors, representing spectral envelopes, and other signal properties that are usually discarded during feature extraction but that are useful for separating nonstationary noise from speech. Specifically, we assume the availability of a noise power spectrum estimator that can capture rapid changes in noise characteristics by leveraging such signal properties. NMT determines the optimal transformation from the estimated noise power spectra into the feature-domain noise model parameter values in the sense of maximum likelihood. NMT is successfully applied to meeting speech recognition, where the main noise sources are competing talkers; and reverberant speech recognition, where the late reverberation is regarded as highly nonstationary additive noise.