gebhart/patrepeval huggingface dataset:
On range and attitude estimation (2002)

Two algorithms to support an airborne, gimballed, electro-optical sensor are described. They have been designed for "Litening", a new targeting and navigation pod, which has been developed by Rafael. A full inertial measurement unit (IMU), capable of measuring linear acceleration and angular velocity, in three orthogonal axes, is mounted in the inner-most gimbal. The first algorithm estimates the attitude of the sensor line of sight (LOS). This estimation, accompanied by on-line sensor calibration, is carried out by a multi-state, multi-measurement Kalman filter, which is integrated within a strapdown navigation system. The second algorithm deals with the range (from a ground target) estimation. A new, linear (!), range estimation problem is formulated. Due to available data, range dynamics is presented as a linear, time varying system. A linear measurement equation, based on an appropriate error model, is obtained as well.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein–ε (2001)

Neutrophil-specific granule deficiency (SGD) is a rare congenital disorder. The neutrophils of individuals with SGD display atypical bi-lobed nuclei, lack expression of all secondary and tertiary granule proteins, and possess defects in chemotaxis, disaggregation, receptor up-regulation, and bactericidal activity, resulting in frequent and severe bacterial infections. Previously, a homozygous mutation in the CCAAT/enhancer binding protein-epsilon (C/EBPepsilon) gene was reported for one case of SGD. To substantiate the role of C/EBPepsilon in the development of SGD and elucidate its mechanism of inheritance, the mutational status of the gene was determined in a second individual. An A-nucleotide insertion in the coding region of the C/EBPepsilon gene was detected. This mutation completely abolished the predicted translation of all C/EBPepsilon isoforms. Microsatellite and nucleotide sequence analyses of the C/EBPepsilon locus in the parents of the proband indicated that the disorder may have resulted from homozygous recessive inheritance of the mutant allele from an ancestor shared by both parents. The mutant C/EBPepsilon(32) protein localized in the cytoplasm rather than the nucleus and was unable to activate transcription. Consistent with this, a significant decrease in the levels of the messenger RNAs (mRNAs) encoding the secondary granule protein human 18-kd cationic antimicrobial protein (hCAP-18)/LL-37 and the primary granule protein bactericidal/permeability-increasing protein were observed in the patient. The hCAP-18 mRNA was induced by overexpression of C/EBPepsilon(32) in the human myeloid leukemia cell line, U937, supporting the hypothesis that C/EBPepsilon is a key regulator of granule gene synthesis. This study strongly implicates mutation of the C/EBPepsilon gene as the primary genetic defect involved in the development of neutrophil SGD and defines its mechanism of inheritance.
Structural characterization of the α‐hemolysin monomer from <i>Staphylococcus aureus</i> (2008)

Alpha-hemolysin from Staphylococcus aureus is secreted as a water-soluble monomer and assembles on membranes to oligomerize into a homo-heptameric, water-filled pore. These pores lead to lysis and cell death. Although the structure of the heptameric pore is solved by means of X-ray crystallography, structures of intermediate states-from the soluble monomer to all potential "pre-pore" structures-are yet unknown. Here, we propose a model of the monomeric alpha-hemolysin in solution based on molecular modeling, verified by small angle X-ray scattering data. This structure reveals details of the monomeric conformation of the alpha-hemolysin, for example inherent flexibility, along with definite differences in comparison to the structures used as templates.
EXPLORING THE TENSION BETWEEN STRATEGIC RESOURCE CHARACTERISTICS: EVIDENCE FROM INDIAN SLUM HOUSEHOLDS (2013)

Resource-based theory has identified strategic resources based on the presence of characteristics which include value, rarity, inimitability, and non-substitutability. Each dimension has largely been treated as dichotomous and independent. As a result, Resource-based theory has failed to account for the continuous and interrelated nature of resource characteristics. We advance theory based on the degree of specific resource characteristics and reveal tensions between them. Specifically, we examine how the level of resource inimitability can negatively impact the value of strategic human capital. We test our findings in the under-researched impoverished firm context using a unique sample of Indian slum households and firms.
Basic study of non-contact measurement system for internal defect in solid materials using high-intensity aerial ultrasonic waves (2012)

Recent development work has led to improved methods employing aerial ultrasonic waves for detecting defects in solid materials such as metals, pipe walls, and fiber-reinforced plastics. We considered a new method to attempt detecting defect in solid materials using high-intensity ultrasonic waves and optical equipment. In this report, we examine the effectiveness of the method through experiment and finite-element method analysis.
Micelle exclusion chromatography of inorganic anions (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicelle exclusion chromatography of inorganic anionsTetsuo. OkadaCite this: Anal. Chem. 1988, 60, 15, 1511–1516Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/ac00166a007https://doi.org/10.1021/ac00166a007research-articleACS PublicationsRequest reuse permissionsArticle Views138Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Labor Movement in America (1938)

Journal Article The Labor Movement in America. By Marjorie R. Clark and S. Fanny Simon. (New York: W. W. Norton, 1938. 208 pp. $2.00.) Get access R. C. Miller R. C. Miller Wayne University Search for other works by this author on: Oxford Academic Google Scholar Journal of American History, Volume 25, Issue 2, September 1938, Page 293, https://doi.org/10.2307/1896530 Published: 01 September 1938
Autonomous Driving in the Lung using Deep Learning for Localization (2019)

Lung cancer is the leading cause of cancer-related death worldwide, and early diagnosis is critical to improving patient outcomes. To diagnose cancer, a highly trained pulmonologist must navigate a flexible bronchoscope deep into the branched structure of the lung for biopsy. The biopsy fails to sample the target tissue in 26-33% of cases largely because of poor registration with the preoperative CT map. To improve intraoperative registration, we develop two deep learning approaches to localize the bronchoscope in the preoperative CT map based on the bronchoscopic video in real-time, called AirwayNet and BifurcationNet. The networks are trained entirely on simulated images derived from the patient-specific CT. When evaluated on recorded bronchoscopy videos in a phantom lung, AirwayNet outperforms other deep learning localization algorithms with an area under the precision-recall curve of 0.97. Using AirwayNet, we demonstrate autonomous driving in the phantom lung based on video feedback alone. The robot reaches four targets in the left and right lungs in 95% of the trials. On recorded videos in eight human cadaver lungs, AirwayNet achieves areas under the precision-recall curve ranging from 0.82 to 0.997.
Yoga and Hypnosis (1963)

Abstract The nature of Yoga and Samaädhi (concentration) was described. Two forms of Samaädhi, conscious and unconscious, and the eight aids to Yoga were given some emphasis in the description. A comparison was made between Samaädhi and hypnosis. It was found that whereas the two differ widely in their ultimate objectives, they have many points of functional and methodological similarity. It was suggested that both in Samaädhi and in deep hypnosis, the S is alert, but for all practical purposes, asleep.
Neue Pigmente vom Flavomannin-Typ aus Cortinarius vitellinus (Agaricales) (1973)

The structure of the yellow main pigment of Cortinarius vitellinus has been established as 4-hydroxy-flavomannin-6,6′-dimethyl ether A1 (1). 1 is easily oxidized to a number of quinones, whose structures have been elucidated by mass spectrometry. A nomenclature for stereoisomeric flavomannin derivatives is proposed.
Expression of CD44 in prostate cancer cells: association with cell proliferation and invasive potential. (1995)

High level expression of the cell surface adhesion molecule CD44 standard form and its splice variants, have been causally linked to tumor metastasis. In this study, we investigated the significance of CD44 expression in human prostatic carcinoma cells. Immunocytochemistry showed high level expression of CD44 in cells from a high grade prostate tumor, and two androgen-independent, invasive prostatic carcinoma lines, PC-3 and TSU-Pr1. Normal prostatic epithelial cells and LNCaP, a low metastatic, androgen sensitive cell line, expressed none to a very low level of CD44, although mRNA transcripts were detected in all cell lines. Immunoprecipitation detected two proteins of M(r) approximately 140 kDa and 210 kDa in PC-3, and predominantly the M(r) approximately 95 kDa protein in TSU Pr1, but none in LNCaP. Most importantly, a neutralizing antibody to CD44 inhibited cell proliferation and basement membrane invasive activity, suggesting a definitive role of CD44 in prostate tumor growth and metastasis.
Optical readout of single spins for quantum computing and magnetic sensing (2011)

The ability to measure and manipulate the quantum state of a single spin in a solid state system opens up a broad range of powerful applications ranging from nano probes to quantum information processing. Over the past few years, a number of ground breaking experiments have been conducted on paramagnetic nitrogen vacancy defect centers in diamond, including up to 3-qubit entanglement, single-shot-readout of a nuclear spin, selective access of two coupled centers and magnetic, electric and thermographic sensing at the nanoscale with promising properties in some cases exceeding most currently known techniques. Yet, almost all of the experiments conducted so far focus on centers deeply buried in the diamond, which is undesirable especially for sensing applications, but also in terms of scalability and electronic access to the information. In this work we focus on the spin physics of centers only few nanometers below the surface, where the unique properties of the center are strongly influenced by the external environment. We coherently manipulated and detected single spins at ambient temperature by combining optically detected magnetic resonance with single molecule spectroscopy using a confocal microscope. We measured the spin dephasing behavior and the phase relaxation time and examined the primary sources of decoherence. Furthermore, we observed effects of water, atmosphere and paramagnetic molecules on the coherence and readability of spins in nanodiamonds and demonstrated ways to preserve the coherence using external magnetic fields and a number of different dynamic decoupling pulse sequences. In addition, we measured couplings to proximal nuclear spins by continuous wave spectroscopy and to molecules on the surface by double electron electron resonance. Also, we demonstrate execution of the refined Deutsch-Jozsa algorithm on a nitrogen vacancy center in a nanodiamond. Finally, we propose new technological approach for realtime measurements of magnetic fields using a single spin in diamond. In test measurements using external fields and spatially resolved measurements of the field from a magnetic microwire a sensitivity of a few uT / sqrt(Hz) was achieved.
Aminoacids in the synthesis of heterocyclic systems. The synthesis of methyl 2‐acetylamino‐3‐dimethylaminopropenoate and 2‐(<i>N</i>‐methyl‐<i>N</i>‐trifluoroacetyl)amino‐3‐dimethylaminopropenoate and their application in the synthesis of heterocyclic compounds (1997)

Abstract Methyl (Z)‐2‐acetylamino‐3‐dimethylaminopropenoate (3) was prepared from N ‐acetylglycine (1), which was converted with N,N ‐dimethylformamide and phosphorus oxychloride into 4‐dimethylaminomethylene‐2‐methyl‐5(4 H )‐oxazolone (2), followed by treatment with methanol in the presence of potassium carbonate, into 3. The compound 3 was shown to be a versatile reagent in the synthesis of various heterocyclic systems. With N ‐nucleophiles, such as heterocyclic amines 4, either methyl 2‐acetylamino‐3‐heteroarylaminopropenoates 5 or fused pyrimidinoncs 6 were formed, dependent on the reaction conditions and/or heterocyclic substituents: C ‐nuclcophiles with an active or potentially active methylene group, such as 1,3‐dicarbonyl compounds 7, 8 and 9, substituted phenols 10a,b, naphthols 11, 12a‐c, and substituted coumarin 13a, afforded substituted pyranones 20 and 22, and fused pyranones 21, 23–26. The nitrogen containing heterocycles 14–19 produced pyranoazines 27–31 and pyranoazole 32. In all of these systems the acetylamino group is attached at position 3 of the newly formed pyranone ring. The orientation around the double bond for methyl (Z)‐2‐( N ‐methyl‐ N ‐trifluo‐roacetyl)‐3‐dimethylaminopropenoate (36) was established by X‐ray analysis.
Ordered Media in Chemical Separations (1987)

A brief description of the structural features and relevant properties of different organized assemblies formed from surfactant molecules is presented. Next, the use and application of these organized surfactant systems in separation science is surveyed. Several possible new areas for future developments employing these ordered media are mentioned.
Falls in the Elderly: Reliability of a Classification System (1991)

To determine risk factors for falls, previous studies have classified falls according to the contribution of factors both intrinsic and extrinsic to the host. Due partly to the lack of operational definitions and the absence of information on reliability, no consensus on classification has been reached. Consequently, in a 3-year prospective study of falls occurring in a probability sample of community-dwelling elderly (n = 1,358), a fall classification system was developed and tested for interrater reliability. The 366 falls in the first year of the study were independently classified by two reviewers on the basis of a narrative description and structured interview. The falls in the four major categories of the classification system included: falls related to extrinsic factors (55%), falls related to intrinsic factors (39%), falls from a non-bipedal stance (8%) and unclassified falls (7%). The interrater reliability for the four major categories was 89.9% with a kappa of 0.828. The system provides operational definitions for types of falls and a reliable and flexible method for classifying falls in the elderly.
9-Cis retinoic acid inhibits growth of breast cancer cells and down-regulates estrogen receptor RNA and protein. (1994)

All-trans retinoic acid (tRA) inhibits growth of estrogen receptor-positive (ER+) breast cancer cells in vitro, and a variety of retinoids inhibit development of breast cancer in animal models. 9-cis retinoic acid (9-cis RA) is a naturally occurring high affinity ligand for the retinoid X receptors, as well as the retinoic acid receptors (RARs). Whether 9-cis RA has a different spectrum of biological activity from tRA, which only binds RARs with high affinity, is largely unknown. We studied the effects of 9-cis RA on growth and gene expression in ER+ and ER- human breast cancer cells. 9-cis RA inhibited the growth in monolayer culture of several ER+, but not ER-, cell lines in a dose-dependent manner. Growth inhibition and morphological changes by 9-cis RA were similar to those of tRA, suggesting that the ability to bind both RAR and retinoid X receptors did not significantly augment growth inhibition or confer sensitivity to tRA-resistant lines. MCF-7 cells exposed to 9-cis RA showed a dose-dependent accumulation in G1. Northern analyses showed that RAR-alpha and RAR-beta were not significantly regulated, while RAR-gamma was up-regulated and retinoid X receptor alpha was down-regulated by 9-cis RA. Since interactions between tRA and ER-dependent transcription have recently been reported, we investigated whether these retinoids regulate expression of ER itself or estrogen-responsive genes. Both 9-cis RA and tRA induce down-regulation of ER mRNA and protein in MCF-7 cells. 9-cis RA down-regulates expression of the estrogen-responsive genes PR and pS2 in MCF-7 cells as reported previously for tRA. In several ER-positive subclones, we found that the degree of ER expression and regulation, but not always estrogen-sensitivity, correlates with the growth-inhibitory effects of 9-cis RA. Further, in an ER-, retinoid-unresponsive breast cancer cell line, induced ER expression confers responsiveness to retinoid growth inhibition. These data, combined with reports of additive growth inhibition of tRA and tamoxifen in vitro, suggest that 9-cis RA might augment the ability of tamoxifen to inhibit growth of ER+ breast cancer cells in vivo.
Fe-Cr-Co magnets (1987)

This paper reviews the recent developments of Fe-Cr-Co permanent magnet alloys. The Fe-Cr-Co alloys offer magnetic properties comparable to those of Alnico alloys, but with a distinct advantage of being ductile and containing less cobalt. Considerable effort has been expended in understanding the relationship between the alloy microstructure, chemistry, phase relationship, and permanent magnet properties as well as in processing development for improved coercivity and energy products. In this paper, various aspects of the processing, structure, origin of coercivity, magnet properties, and applications of the Fe-Cr-Co alloys will be discussed.
Seat allocation for massive events based on region growing techniques (2006)

This paper provides a technique for resolving the seat allocation problem for massive events, that consists in distributing people across the stadium keeping the spectators preferences and satisfying rules from the administration. The method is based on a region growing technique inherited from the Computer Vision field, with which a first candidate to the solution is obtained, followed by an improvement process.
SIB and SFA consult on the regulatory responsibilities of senior management of firms doing investment business (1998)

In September 1996 the Securities and Futures Authority (SFA), the self‐regulatory organisation with responsibility under the Financial Services Act 1986 for much of the brokerage and dealing sectors of the financial markets, published a provocative and somewhat controversial consultation document containing proposals to amend its rules governing the responsibilities of senior executive officers. This initiative from the SFA was triggered by the collapse of the Barings group which, with the wisdom of hindsight, was seen to be attributable as much to a lack of quality, effective internal controls and management systems as to Nick Leeson's deception. Hence, the SFA broke new ground in its proposals to include in its rules specific expectations of a firm's senior executive officers as to general management controls and structures within a regulated firm and a particularly controversial proposal to reverse the burden of proof in regulatory disciplinary proceedings against such officers where the firm has suffered a serious financial or reputational damage where SFA suspects that management failure has been a cause or contributing factor.
An Imputation-based Augmented Anomaly Detection from Large Traces of Operating System Events (2017)

Software debugging, audit, and compliance testing are some of the tasks we perform using execution traces of an operating system. However, these actions gather information about the behavior of the software vis-a-vis its design aims. In this work, our analysis of the execution traces of an embedded real-time operating system (RTOS) is rather to model the behavior of the physical system being managed by the software application via the embedded operating system. Hence, for an event-triggered embedded RTOS that controls the behavior of a bespoke system like an unmanned aerial vehicle (UAV), the events in the execution traces of the embedded RTOS is directly linked to the operation of the controlled physical system. Therefore, we hypothesize that the frequency of events (method/function calls) per observation is a useful feature for modeling the behavior of the physical system controlled by the operating system.
Simultaneous induction of matrix metalloproteinase‐9 and interleukin 8 by all‐<i>trans</i> retinoic acid in human PL‐21 and NB4 myeloid leukaemia cells (2002)

All-trans retinoic acid (ATRA) has been shown to induce differentiation of human acute promyelocytic leukaemia (APL) cells and eventual elimination of the malignant clone. Matrix metalloproteinase-9 (MMP-9) is produced by neutrophils and its expression appears to be linked with myeloid cell differentiation. We investigated effects of ATRA on MMP expression in two human myeloid leukaemia cell lines, PL-21 and NB4. Both cells could differentiate into neutrophils after exposure to ATRA. Both the activity and antigen levels of MMP-9 were much higher in NB4 cells than in PL-21 cells. Stimulation with ATRA significantly increased MMP-9 levels approximately three- to fivefold in both PL-21 and NB4-conditioned media. MMP-9 mRNA levels increased in ATRA-treated cells and was almost in parallel with the increase in MMP-9 activity, suggesting that ATRA induced MMP-9 by activating its gene expression. ATRA can induce interleukin 8 (IL-8) in APL cells. IL-8, chemokine for neutrophils and a potent inducer of MMP-9, was also induced by ATRA in PL-21 cells. However, recombinant IL-8 did not induce MMP-9 expression. In addition, a neutralizing antibody against IL-8 did not inhibit ATRA-induced MMP-9 expression in either cell type. These observations suggest that ATRA can induce both MMP-9 and IL-8, but IL-8 is not involved in ATRA-induced MMP-9 expression. As MMP-9 can truncate and activate IL-8, simultaneous induction of MMP-9 and IL-8 by ATRA could activate leucocytes excessively, causing the hyper-inflammatory events in retinoic acid syndrome.