gebhart/patrepeval huggingface dataset:
A Novel, One‐Pot Synthesis of Novel 3F, 5F, and 8F Aromatic Polymers (2007)

Abstract A series of novel, linear, soluble, high‐molecular‐weight, fluorinated aromatic polymers has been obtained for the first time using a superacid‐catalyzed polyhydroxyalkylation reaction of fluorinated carbonyl‐containing compounds: 1,1,1,‐trifluoroacetone ( 1 ), 2,2,2‐trifluoroacetophenone ( 2 ), 2,3,4,5,6,‐pentafluorobenzaldehyde ( 3 ), and octafluoroacetophenone ( 4 ) with aromatic hydrocarbons such as biphenyl ( a ), phenyl ether ( b ), terphenyl ( c ), and 4,4′‐diphenoxybenzophenone ( d ). These Friedel‐Crafts‐type aromatic electrophilic substitution reactions are performed at room temperature in trifluoromethane sulfonic acid or in its mixtures with dichloromethane. The polymers obtained are soluble in common organic solvents, and colorless transparent films could be cast from the solutions. 1 H and 13 C NMR analyses of the polymers synthesized reveal their linear, highly regular structure. The polymers also possess high thermostability. magnified image
Post menopausal bleeding as a risk factor for endometrial carcinoma. (1991)

From July 1985 to January 1989, 133 patients underwent endometrial sampling for evaluation of post menopausal bleeding (PMB). Of these patients, 114 (85.7 percent) showed benign histology with an average age of 58.6 years. Nineteen (14.3 percent) were malignant, all of which showed endometrial carcinoma. The average age was 65. In addition, 26.3 percent of patients with carcinoma had higher grade of tumor at hysterectomy when compared with the preoperative biopsy. The average volume of tissue removed at curettage was significantly greater in those with carcinoma. Hormonal therapy, duration of symptoms, hypertension, obesity or diabetes were not significant risk factors for carcinoma in our series. PMB remains a major symptom that may predict endometrial carcinoma and must be evaluated. In those patients with carcinoma, intraoperative evaluation of the uterus for tumor grade and depth of invasion is important in determining the extent of surgery.
Organics, polymers and nanotechnology for radiation hardening and shielding applications (2007)

Recent studies have indicated that polymers integrated with nanoparticles and nanostructures have a high potential for increasing the space radiation resistance and hardening of photonic and electronic components. Discussed within this paper are recent data which support the premise that certain nanotechnology may improve the radiation resistance of organics, polymers, biopolymers and hybrid polymer-inorganic materials and devices to ionizing and displacement radiations. These materials are also being investigated for their ability to provide protective radiation shielding to a wide spectrum of radionuclide and galactic cosmic ray emissions such as alpha particles, protons, electrons, gamma-rays, beta rays, x-rays and neutrons. The appeal for advancing nanotechnology based materials and devices in many cases centers on the rapid development of hardened, economical and lightweight technologies that surpass the performance of current photonic, biotronic and microelectronic device and material technologies.
Image retrieval on the Honeycomb Image Browser (2010)

Efficient and effective approaches of dealing with the vast amount of visual information available nowadays are highly sought after. This is particularly the case for image collections, both personal and commercial. Due to the magnitude of these ever expanding image repositories, annotation of all images images is infeasible, and search in such an image collection therefore becomes inherently difficult. Although content-based image retrieval techniques have shown much potential, such approaches also suffer from various problems making it difficult to adopt them in practice. In this paper, we follow a different approach, namely that of browsing image databases for image retrieval. In our Honeycomb Image Browser, large image databases are visualised on a hexagonal lattice with image thumbnails occupying hexagons. Arranged in a space filling manner, visually similar images are located close together enabling large image datasets to be navigated in a hierarchical manner. Various browsing tools are incorporated to allow for interactive exploration of the database. Experimental results confirm that our approach affords efficient image retrieval.
Colorimetric capture assay for human-immunodeficiency-virus-I reverse transcriptase activity. (1999)

The development of a colorimetric capture assay for HIV-1 reverse transcriptase (RT) activity is described. This assay consisted of three basic steps: enzyme purification, RT reaction and product detection, which were all performed in the same microtitre plate. Mouse monoclonal anti-RT antibodies of subclass G2a were bound by polyclonal goat anti-(mouse IgG2a) immobilized in the wells of a microtitre plate. The monoclonal antibodies (mAbs) were selected for their ability to bind HIV-1 RT without hampering the polymerase activity. The assay system first involved the RT's adherence to the immobilized mAbs. Non-specific enzymes and other impurities were removed by a simple wash, after which an RT reaction mixture containing BrdUTP as nucleotide substrate was added. After the RT reaction substrate and product had been separated by washing of the plate, the amount of BrdUMP-DNA in the wells was finally detected with alkaline-phosphatase-conjugated mouse anti-BrdU antibodies of subclass IgG1. The background signal in this system was similar to the signals obtained with control wells coated with BSA only. A detection limit of 1.2 micro-units of RT activity, corresponding to 0.3 pg of RT protein, was obtained for the capture assay when applying colorimetric product detection. The assay detected RTs from HIV-1 subtypes A and B and one of the two D type isolates tested. None of the five non-HIV-1 RTs tested was found positive. At least 50 microl of human serum or plasma per sample could be included in the capture assay without adverse effects on the recovery of the RT activity.
A 2Gpixel/s H.264/AVC HP/MVC video decoder chip for Super Hi-Vision and 3DTV/FTV applications (2012)

8K×4K Super Hi-Vision (SHV) offers a significantly enhanced visual experience relative to 1080p, and is on its way to being the next digital TV standard. In addition, advanced 3DTV specifications involving a large number of camera views are targeted by emerging applications such as free-viewpoint TV (FTV). This paper presents a single-chip design that supports real-time H.264 decoding of SHV or up to 32 HD views. The design of the chip involved 3 key challenges: 1) Data dependencies of video coding algorithms restrict the degree of hardware parallelism. For SHV, each macroblock (MB) should be processed in less than 40 cycles at 300MHz, which is difficult to meet with a single pipeline; 2) due to the massive design and verification effort for video decoders, a scalable architecture that allows the maximum reuse of existing IP is desirable; and 3) the DRAM bandwidth requirements are always a bottleneck in high-throughput video decoders.
<title>Transfer of micro-optical structures into GaAs and diamond</title> (2001)

Transfer of continuous-relief micro-optical structures from resist into GaAs, by use of direct-write electron-beam lithography followed by dry etching in an inductively coupled plasma, is demonstrated. A BCl<SUB>3</SUB>/Ar chemistry has been found to give satisfactory results, N<SUB>2</SUB> and Cl<SUB>2</SUB> have been added to change the selectivity between GaAs and e-beam resist. The transfer process generates smooth etched structures. Distortion of the diffractive structures in the transfer process has been examined. Blazed gratings with a period of 10 micrometers have been optically evaluated using a 940 nm VCSEL. The diffraction efficiency was 67% in the first order with a theoretical value of 87%. Also, simulations of the optical performance for the transfered diffractive elements have been made using Fourier transform of the grating profile. For integrating the optical element with VCSELs there are several possible alternatives. We have fabricated the optical structure on the same substrate that is used for the VCSEL and characterization is presently under way. We also show our initial results on transfer of micro-optical structures from resist into diamond using dry etching.
Using crop simulation to generate genotype by environment interaction effects for sorghum in water-limited environments (2002)

Multi-environment trials (METs) used to evaluate breeding lines vary in the number of years that they sample. We used a cropping systems model to simulate the target population of environments (TPE) for 6 locations over 108 years for 54 ‘near-isolines’ of sorghum in north-eastern Australia. For a single reference genotype, each of 547 trials was clustered into 1 of 3 ‘drought environment types’ (DETs) based on a seasonal water stress index. Within sequential METs of 2 years duration, the frequencies of these drought patterns often differed substantially from those derived for the entire TPE. This was reflected in variation in the mean yield of the reference genotype. For the TPE and for 2-year METs, restricted maximum likelihood methods were used to estimate components of genotypic and genotype by environment variance. These also varied substantially, although not in direct correlation with frequency of occurrence of different DETs over a 2-year period. Combined analysis over different numbers of seasons demonstrated the expected improvement in the correlation between MET estimates of genotype performance and the overall genotype averages as the number of seasons in the MET was increased.
Analgesic effect of intrathecally administered orexin‐A in the rat formalin test and in the rat hot plate test (2002)

1. Orexin-A and orexin-B (also known as hypocretin-1 and hypocretin-2) are hypothalamic peptides and regulate feeding behaviour, energy metabolism and the sleep-wake cycle. Orexin-A binds equally to both orexin-1 and orexin-2 receptors, while orexin-B has a preferential affinity for orexin-2 receptors. 2. Orexins are also known to be concentrated in superficial laminae of the spinal dorsal horn, and orexin-A and orexin-1 receptors are found in the dorsal root ganglion cells. 3. In the present study, the authors examined the effect of intrathecal injection of either orexin-A or orexin-B in the rat formalin test (a model of inflammatory pain) and in the rat hot plate test. The paw formalin injection induces biphasic flinching (phase 1: 0-6 min; phase 2: 10-60 min) of the injected paw. 4. Intrathecal injection of orexin-A, but not orexin-B, decreased the sum of flinches in phases 1 and 2 in the formalin test and increased the hot plate latency. These effects of orexin-A were completely antagonized by pre-treatment with SB-334867, a selective orexin-1 receptor antagonist. Intrathecal injection of SB-334867 alone had no effect in the formalin test or in the hot plate test. 5. Intrathecal injection of orexin-A suppressed the expression of Fos-like immunoreactivity (Fos-LI), induced by paw formalin injection, in laminae I-II of L4-5 of the spinal cord. 6. These data suggest that the spinal orexin-1 receptor is involved in the nociceptive transmission and that the activation of the spinal orexin-1 receptor produces analgesic effects in the rat formalin test and in the rat hot plate test.
The planning and establishment of the Grootegeluk Coal Mine (1982)

This paper indicates how the South African Iron and Steel Industrial Corporation Limited (Iscor), as a major consumer of raw materials, determines the tonnage and quality of essential raw materials required to satisfy an increasing demand for steel and how this led to the establishment of a coal mine with a highly sophisticated beneficiation plant in the Waterberg coalfield, near Ellisras in the Transvaal. The planning of the project, with specific reference to the limited reserves of metallurgical coal in South Africa, the quality and quantity ofthe coal to be produced, and the way in which the project was managed is discussed briefly.
Genetic divergence among maize (Zea mays L.) inbreds and restricting traits for group constellation (2004)

Genetic divergence among thirty two maize inbred lines were studied through multivariate analyses. Genetic distance was measured following D2 statistic and inbreds were grouped into fourteen distinct clusters. Intra and inter cluster distances among the groups were determined and analyzed with respect to the cluster means. Two methods, B2 and B4, reported by Jolliffe, were used for restricting the number of variables in group constellation. Ten out of 20 traits were curtailed following each of the two methods. After this D2 values were recalculated and groups were reconstituted and compared with the original clusters using 20 variables. The clustering of the 32 inbreds based on D2 values obtained from 10 selected characters for each of the two methods (B2 and B4) of discarding variables were different with respect to the number of clusters formed and inbred. Included in the clusters. The clustering pattern following selection of variables based on B2 method deviated considerably from the original clusters. Whereas clustering pattern based on B4 method of discarding variable was similar to the original clusters, hence seeme more appropriate and efficient in the study.
In This Issue, Volume 11, Issue 2 (2020)

ADVERTISEMENT RETURN TO ISSUEIn This IssueNEXTIn This Issue, Volume 11, Issue 2Terry W. MooreTerry W. MooreMore by Terry W. Moorehttp://orcid.org/0000-0002-5410-306XCite this: ACS Med. Chem. Lett. 2020, 11, 2, 90Publication Date (Web):February 13, 2020Publication History Published online13 February 2020Published inissue 13 February 2020https://pubs.acs.org/doi/10.1021/acsmedchemlett.0c00038https://doi.org/10.1021/acsmedchemlett.0c00038in-briefACS PublicationsCopyright © 2020 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views444Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (707 KB) Get e-AlertscloseSUBJECTS:Inhibition,Inhibitors,Monomers,Peptides and proteins,Tumors Get e-Alerts
High-k metal-gate PMOS FinFET threshold voltage tuning with aluminum implantation (2012)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation K. V. Rao, T. Ngai, C. Hobbs, M. Rodgers, S. Vivekanand, V. Chavva, F. Khaja, T. Henry, K. H. Shim, P. Kirsch, R. Jammy; High-k metal-gate PMOS FinFET threshold voltage tuning with aluminum implantation. AIP Conf. Proc. 6 November 2012; 1496 (1): 38–41. https://doi.org/10.1063/1.4766484 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Automatic vision inspection system for the analysis and detection of breakages and defects of satsuma slices (2002)

Quality standards for preserved vegetables establish, among others, commercial categories for satsuma (mandarin variety) according to the percentage of broken slice, slice fragments and peeling defects. The detection process of these defects is made, nowadays, by means of visual inspection and manual separation. This paper reveals the development and implementation of an automatic inspection system based on color image processing and techniques, used for detection, segmentation, identification of the satsuma slices, with the final aim of an a posteriori slice classification, according to the percentage of broken slices.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Absorbed dose water calorimeter (1980)

Advantage was taken of the low thermal diffusivity of water and the imperviousness of polyethylene film to water to construct a calorimeter for directly measuring absorbed dose in that medium. An ultrasmall bead thermistor was sandwiched between two thin films stretched on polystyrene rings and immersed in an unregulated water bath. Ten cobalt-60 irradiation runs were made with a precision of 0.5% mean error of the mean at a dose rate of 66 mGy/s. Further development is directed toward a standard instrument that can be used in a medical therapy beam.
Drug repositioning by integrating target information through a heterogeneous network model (2014)

Supplementary data are available at Bioinformatics online.
Analysis of Elderly Mobility by Structural Equation Modeling (2003)

Mobility is a critical element of quality of life. This is as true for the elderly population as for the larger population. The elderly often have limited physical abilities and financial constraints that might reduce their mobility. Helping the growing elderly population to maintain decent mobility is a critical challenge for transportation planning and policy. For this, the factors that influence the mobility of the elderly population (elderly mobility) must be understood. Only a few systematic studies, however, have been published. Descriptive statistics of the potentially influential factors make it difficult to assess their effects on elderly mobility. The transportation mobility of retired people age 65 years or older in the Puget Sound region of Washington State was analyzed by using a structural equation model. The statistical significance and relative effects of various personal and household characteristics and urban form on elderly mobility were tested. The structural equation model finds statistically significant relationships between age, gender, transportation disability, possession of a driver's license, and education level and elderly mobility. Among these variables, age and education level show the strongest effects. Urban form, however, seems to be insignificant.
HIM0S-a high efficiency flash E/sup 2/PROM cell for embedded memory applications (1993)

A flash E/sup 2/PROM device which is programmed with a highly efficient hot-electron injection mechanism is described. This high-injection MOS (HIMOS) device combines a very high programming speed at 5-V-only operation with a low development entry cost, which renders it highly attractive for embedded memory applications. The HIMOS concept exhibits complete soft-write immunity and the possibility of overerasure without causing any problem in a memory architecture. It is shown that this device can also operate with a 3.3-V voltage supply, which is of a major importance for the next generation of submicron flash E/sup 2/PROM technologies.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Impairment of nucleoid segregation and cell division at high osmolarity in a strain of Escherichia coli overproducing the chaperone DnaK (1993)

Escherichia coli strain WM1390, which overproduces 20-fold the chaperone protein DnaK, was able to grow exponentially without apparent abnormality in 300 mosM medium. In contrast, it showed both aberrant nucleoid segregation and strong inhibition of septation when shifted to high osmolarity. These impairments could not be accounted for by a bacteriocidal effect of the high DnaK content. Rather, the DnaK content appeared to promote faster growth than that of the parent C600, at least at high osmolarity in the presence of the osmoprotectant glycine betaine.
Feasibility of Electrolyte Regeneration in Al Batteries (1962)

The feasibility of electrolyte regeneration was proved by a continuous current-drain experiment of more than 100- h duration. The initial electrolyte consisted of 120 cc 3.0M KOH solution. The total current drain amounted to more than 80 A-h (at around 1.5 V and 20 mA/cm/sup 2/), which is equivalent to more than 3 times the discharge expected without electrolyte regeneration.
Increasing Ang1/Tie2 expression by simvastatin treatment induces vascular stabilization and neuroblast migration after stroke (2008)

In this study, we tested the hypothesis that the Angiopoietin 1 (Ang1)/Tie2 pathway mediates simvastatin-induced vascular integrity and migration of neuroblasts after stroke. Rats were subjected to 2 hrs of middle cerebral artery occlusion (MCAo) and treated, starting 1 day after stroke with or without simvastatin (1 mg/kg, daily) for 7 days. Simvastatin treatment significantly decreased blood-brain barrier (BBB) leakage and concomitantly, increased Ang1, Tie2 and Occludin expression in the ischaemic border (IBZ) compared to the MCAo control group. Simvastatin also significantly increased doublecortin (DCX, a marker of migrating neuroblasts) expression in the IBZ compared to control MCAo rats. DCX was highly expressed around vessels. To further investigate the signalling pathway of simvastatin-induced vascular stabilization and angiogenesis, rat brain microvascular endothelial cell (RBMEC) culture was employed. The data show that simvastatin treatment of RBMEC increased Ang1 and Tie2 gene and protein expression and promoted phosphorylated-Tie2 activity. Simvastatin significantly increased endothelial capillary tube formation, an index of angiogenesis, compared to non-treated control. Inhibition of Ang1 or knockdown of Tie2 gene expression in endothelial cells significantly attenuated simvastatin-induced capillary tube formation. In addition, simvastatin significantly increased subventricular zone (SVZ) explant cell migration compared to non-treatment control. Inhibition of Ang1 significantly attenuated simvastatin-induced SVZ cell migration. Simvastatin treatment of stroke increases Ang1/Tie2 expression and thereby reduces BBB leakage and promotes vascular stabilization. Ang1/Tie2 expression induced by simvastatin treatment promotes neuroblast micro-vascular coupling after stroke.