gebhart/patrepeval huggingface dataset:
Isolamento e seleção de fungos filamentosos do solo de sistemas agroflorestais do Município de Bom Jardim (PE) com base na capacidade de produção de enzimas hidrolíticas (2011)

O presente trabalho teve por objetivo isolar e identificar fungos de solo de sistemas agroflorestais e avaliar a atividade enzimática destes fungos. Estes foram isolados pela técnica de diluição sucessiva e avaliados quanto à capacidade de degradar amido, celulose e caseína. Foram identificadas 11 espécies de fungos anamorfos (Hyphomycetes) distribuídos em cinco gêneros: Aspergillus, Cladosporium, Curvularia, Fusarium e Penicillium. As espécies estudadas não apresentaram atividade amilolítica satisfatória. Cladosporium cladosporioides (Fres.) De Vries e Penicillium chrysogenum Thom apresentaram maior índice de relação enzimática (IRE) para protease e celulase. Entre as espécies estudadas seis apresentaram maior Índice de Relação Enzimática (IRE) para celulase em comparação as demais enzimas.
Toxicodynamics of Itraconazole: Implications for Therapeutic Drug Monitoring (2009)

We explored concentration-toxicity relationships for itraconazole among 216 patients. Logistic regression revealed a progressive increase in the probability of toxicity with increasing concentrations of itraconazole. Classification and regression tree analysis suggested that 17.1 mg/L of itraconazole (measured using a bioassay) was the concentration level at which the population of patients was separated into 2 groups, each with a high and a low probability of toxicity.
A fundamental investigation about maximum torque control of synchronous reluctance motor (2003)

Synchronous reluctance motors (SynRMs) can be made of iron and copper. Therefore, they are suitable for low cost manufacturing and recycling when no longer operable. However, SynRMs have nonlinear inductance characteristics and nonlinear torque characteristics. So it is important to clarify those characteristics for SynRM control. In this paper, we manufactured an experimental SynRM with 4 poles. Measured results for inductance and torque characteristics of the motor are shown. We achieve maximum torque control of SynRM. The effectiveness of this control is shown by experimental results.
Electrotherapy of the Heart: Technical Aspects in Cardiac Pacing (1992)

Basic anatomy and physiology of the heart physiology of the heartbeat monitoring the electrical activity of the heart pathophysiology therapy for cardiac rhythm disturbances pacemaker technology control aspects of cardiac output adjustment status of the application of corporeal control parameters cardiac control parameters the stimulating electrode materials in pacemaker technology pacemaker power sources re-establishment of physiological regulation a challenge to technology.
Fluorescence from dentin and cementum in human mandibular second premolars and its relation to age (1989)

Investigations were carried out to study the fluorescent properties of human dentin and cementum and their relation to age. One hundred mandibular second premolars were ground according to the "half tooth" technique. The intensity of the red fluorescence was measured during illumination of dentin and cementum with a green light. The results were analyzed with the use of the SPSS. The intensity of the fluorescent light recorded from cementum was stronger than that recorded from dentin. A paired t-test showed no statistically significant left/right difference in fluorescence. Pearson's correlation coefficient indicated a strong relationship between age and fluorescence from dentin (r = 0.73) and from cementum (r = 0.77). The sex of the individual had no significant influence on the fluorescence. Teeth removed from decreased individuals emitted fluorescence with a slightly stronger intensity than did teeth extracted from living patients. Regression analysis indicated a linear relationship between age and the fluorescence from either dentin or cementum. There was a strong correlation between the intensity of the fluorescence and color estimates from the same teeth and the partial correlation coefficient was still statistically significant when controlling for the effect of age.
Fifty Years of Ferroelectricity (1971)

Developments in the field of ferroelectricity are traced from the discovery of the ferroelectric effect by Joseph Valasek in 1921 to its use in a variety of modern applications. Its appearance and utilization in different substances is discussed.
Pathological Complete Response and Accelerated Drug Approval in Early Breast Cancer (2012)

Neoadjuvant trials introduce new drugs preoperatively in patients with localized breast cancer, using the rate of pathological complete response as the primary end point. The FDA has issued guidance for using this end point in applying for accelerated drug approval.
ZeroSDN: A Highly Flexible and Modular Architecture for Full-Range Distribution of Event-Based Network Control (2018)

Recent years have seen an evolution of software-defined networking (SDN) control plane architectures, starting from simple monolithic controllers, over modular monolithic controllers, to distributed controllers. We observe, however, that today's distributed controllers still exhibit inflexibility with respect to the distribution of control logic. Therefore, we propose a novel architecture of a distributed SDN controller, providing maximum flexibility with respect to distribution and improved manageability. Our architecture splits control logic into lightweight control modules, called controllets, based on a micro-kernel approach, reducing common controllet functionality to a bare minimum and factoring out all higher-level functionality. Lightweight controllets also allow for pushing control logic onto switches and enable local processing of data plane events to minimize control latency and communication overhead while leveraging SDN's global view to maximize control decision quality. Controllets are interconnected through a message bus supporting the publish/subscribe communication paradigm with specific extensions for content-based message filtering. Publish/subscribe allows for complete decoupling of controllets to further facilitate control plane distribution. Furthermore, we identify crucial requirements for practical on-switch deployments, where we employ lightweight virtualization techniques to ensure a safe control plane operation. We evaluate both, the scalability and performance properties of our architecture, including its deployment on a white-box networking hardware switch.
Active learning for statistical phrase-based machine translation (2009)

Statistical machine translation (SMT) models need large bilingual corpora for training, which are unavailable for some language pairs. This paper provides the first serious experimental study of active learning for SMT. We use active learning to improve the quality of a phrase-based SMT system, and show significant improvements in translation compared to a random sentence selection baseline, when test and training data are taken from the same or different domains. Experimental results are shown in a simulated setting using three language pairs, and in a realistic situation for Bangla-English, a language pair with limited translation resources.
Biochemistry of Genetic Recombination: Energetics and Mechanism of DNA Strand Exchange (1991)

Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More
High resolution catadioptric omni-directional stereo sensor for robot vision (2004)

Autonomous robots need to acquire both omnidirectional view and stereo in real-time without sacrificing too much image resolution. The recent catadioptric omni-directional vision sensors provide simple affordable real-time omni-directional images but only at the cost of rather low image resolutions. This work describes a novel omni-directional stereo image sensor providing the highest resolution while still retaining the simplicity and real-time advantages that are unique to the family of catadioptric sensors. Only one simple reflective surface, a beam splitter and two regular (perspective) cameras are needed.
Pharmacologic responsiveness of isolated single eccrine sweat glands (1981)

Pharmacologic responsiveness of the eccrine sweat gland has never been studied under well-defined in vitro experimental conditions. Using isolated cannulated single monkey palm eccrine sweat glands, the dose response to both cholinergic and alpha- and beta-adrenergic agents and the effects of various antagonists on agonists were studied. The maximal sweat rate was highest after stimulation with cholinergic agonists, was lower with the beta-adrenergic agonist, and was least with the alpha-adrenergic agonist. Each secretory response was inhibited by its specific antagonist. Attempts to demonstrate the spare receptor, if any, by means of preincubation of the glands with N-(2-chlorethyl)dibenzylamine (Dibenamine) were unsuccessful. From the hyperbolic dose-response curves the values for KA and KB, dissociation constants for agonists and antagonists, respectively, were thus tentatively estimated according to Clark's classical receptor theory. Schild plots for each agonist-antagonist interaction produced straight lines with slopes of near unity, indicating the adequacy of the methodology. It was concluded that the isolated eccrine sweat glands retain their pharmacologic viability in vitro and show responsiveness to cholinergic as well as both alpha- and beta-adrenergic stimulations.
Chemotactic desensitization of neutrophils demonstrates interleukin-8 (IL-8)-dependent and IL-8-independent mechanisms of transmigration through cytokine-activated endothelium. (1993)

We have recently shown that an exogenous gradient of interleukin-8 (IL-8) induces the transendothelial migration of neutrophils. Treatment of endothelium with the cytokines IL-1 or tumour necrosis factor (TNF) also causes neutrophil transmigration, and recent evidence suggests that this may be due to endogenous IL-8 produced by the endothelium. We have used specific chemotactic desensitization of neutrophils to investigate the role of IL-8 in transmigration through cytokine-activated endothelium. Preincubation of neutrophils with IL-8 reduced their chemotactic transmigration response to an IL-8 gradient by 81%, demonstrating desensitization. Transmigration in response to cytokine-activated endothelium was inhibited by 104% after IL-8 preincubation, thus tending to support the role of IL-8. However, preincubation with another neutrophil chemotactic factor N-formyl-methionyl-leucyl-phenylalanine (FMLP), which did not affect the IL-8, response, also inhibited transmigration, by 74%. This suggests that FMLP preincubation acts to inhibit a non-IL-8-dependent mechanism of transmigration through cytokine-activated endothelium. Chemotactic factor pretreatment of neutrophils did not reduce their adhesion to activated endothelium, but specifically blocked the transmigration step. We have therefore shown that chemotactic transmigration can be subjected to factor-specific desensitization, and have used this to provide evidence supporting a role for IL-8 in transmigration through cytokine-activated endothelium, as well as suggesting a further IL-8-independent mechanism. These data also provide a mechanism for the observed defect in accumulation of neutrophils at inflammatory sites when chemotactic factors are infused intravenously.
Down‐regulation of ARC contributes to vulnerability of hippocampal neurons to ischemia/hypoxia (2003)

ARC is a caspase recruitment domain-containing molecule that plays an important role in the regulation of apoptosis. We examined ARC expression during neuronal cell death following ischemic injury in vivo and in vitro. After exposure to transient global ischemic conditions, the expression of ARC was substantially reduced in the CA1 region of hippocampus in a time-dependent manner with concomitant increase of TUNEL-positive cells. Quantitative analysis using Western blotting exhibited that most of ARC protein disappeared in the cultured hippocampal neurons exposed to hypoxia for 12 h and showing 60% cell viability. Forced expression of ARC in the primary cultures of hippocampal neurons or B103 neuronal cells significantly reduced hypoxia-induced cell death. Further, the C-terminal P/E rich region of ARC was effective to attenuate hypoxic insults. These results suggest that down-regulation of ARC expression in hippocampal neurons may contribute to neuronal death induced by ischemia/hypoxia.
Utilization of Carbon Sources by <i>Pullularia pullulans</i> for the Elaboration of Extracellular Polysaccharides (1971)

The yeastlike fungus Pullularia pullulans utilizes simple mono- and disaccharides both in the production of cell mass and the elaboration of extracellular polysaccharide. The utilization pattern of these sugars and the effect obtained by varying the pH of the medium are studied, and the ability of the organism to utilize and elaborate extracellular polysaccharides from noncarbohydrate sources is explored.
Different inhibitory effect of imatinib on phosphorylation of mitogen‐activated protein kinase and Akt and on proliferation in cells expressing different types of mutant platelet‐derived growth factor receptor‐α (2004)

Most gastrointestinal stromal tumors (GISTs) have gain-of-function mutations of the c-kit gene. Previously, we found 2 types of gain-of-function mutation of the PDGFRA gene, Val561 to Asp and Asp842 to Val, in about half of GISTs without c-kit gene mutations. Although the inhibitory effect of imatinib on various types of activating mutant KIT has been well examined, that on the activating mutant PDGFRA has not been fully investigated. In the present study, we examined the effect of imatinib on autophosphorylation of mutant PDGFRA, phosphorylation of MAPK and of Akt and in vitro cell proliferation using murine Ba/F3 cells stably transfected with one of the 2 murine-type mutated PDGFRA cDNAs. Imatinib almost completely inhibited autophosphorylation of mutant PDGFRA, phosphorylation of MAPK and Akt as well as in vitro cell proliferation at the concentration of 0.01 microM in cells expressing mutant PDGFRA with Val561 to Asp. However, in cells expressing mutant PDGFRA with Asp842 to Val, imatinib almost completely inhibited autophosphorylation of mutant PDGFRA and phosphorylation of MAPK and Akt at 1.0 microM. The concentration contributing to complete inhibition of in vitro cell proliferation was 10 microM. Ba/F3 cells expressing mutant PDGFRA are a good model to investigate the mechanism of cell proliferation or growth inhibition by imatinib in mutant PDGFRA-driven cells.
An ALife approach to modeling virtual cities (2002)

This paper proposes a novel method that enables automatic modeling of virtual cities. The method makes use of L-systems to generate road networks and the genetic algorithm (GA) to generate building layouts. The road networks are composed of two types of roads-linear flow systems which are generated by using the Tree L-system and cellular networks which are generated by using the Map L-system. A generation procedure for road networks and building layouts is described. Some experimental results of generated road networks and virtual cities are also shown.
Development of a valid and reliable blood stasis questionnaire and its relationship to heart rate variability (2013)

Our results suggest that the BSQ is a valid and reliable instrument for evaluating BS and BS may partially cause a decrease in cardiovascular autonomic function.
Improving the quality of the credit authorization process (2001)

This paper proposes that the quality of a company’s authorization system should be measured by two major considerations. First, the system should enhance the quality of customer service by reducing the waiting time at the point of sale. Second, it should reduce the risk of accepting transactions of bad credit. In this paper, a major credit card company is used to demonstrate how the credit authorization process can be improved using a quantitative approach. Opportunities for quality improvement were first identified through brainstorming sessions with top management, using quality improvement tools. A new sampling inspection scheme was then developed, based on analysis of the risk of requests for transactions in different industries. With the new inspection scheme, the total inspection cost was significantly reduced. A queuing model was then used to redesign the authorization process. Finally, a simulation model was used to test and evaluate the new process design. As a result of these improvements, it was determined that more than US$2.5 million was saved annually and authorization efficiency was improved by more than 40 per cent.
Liquid chromatography/particle beam/mass spectrometry of polar compounds of environmental interest (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLiquid chromatography/particle beam/mass spectrometry of polar compounds of environmental interestThomas D. Behymer, Thomas A. Bellar, and William L. BuddeCite this: Anal. Chem. 1990, 62, 15, 1686–1690Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/ac00214a031https://doi.org/10.1021/ac00214a031research-articleACS PublicationsRequest reuse permissionsArticle Views109Altmetric-Citations90LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A DNA-flow cytometric analysis of trichilemmal carcinoma, proliferating trichilemmal cyst and trichilemmal cyst. (1994)

In patients with systemic sclerosis peristaltic abnormalities may delay gastric emptying, giving rise to bacterial overgrowth, including possibly Helicobacter pylori (HP). Infection with Helicobacter is an important risk factor for esophageal and gastric diseases, including esophagitis, gastritis and gastric cancer. The purpose of this prospective study was to assess gastric HP infection in patients with systemic sclerosis. In 12 patients with systemic sclerosis the newly introduced breath test with 13C-labelled urea was used for indirect detection of gastric urease activity due to HP infection. Five out of 12 patients gave Helicobacter-positive results (42%); 7 patients were negative for Helicobacter colonization (58%). Thus, the risk for gastric diseases caused by HP infection is enhanced in patients with systemic sclerosis compared with white healthy, asymptomatic persons examined in other studies. Helicobacter-positive patients were treated with 2 x 20 mg omeprazole and 4 x 500 mg amoxicillin over 14 days. Afterwards the 13C-urea breath test was repeated and showed negative results for Helicobacter in all systemic sclerosis patients treated. Dual therapy with omeprazole and amoxicillin therapy effectively eradicated HP. The 13C-urea breath test did not cause any side-effects and is therefore considered to be a non-invasive, non-toxic and safe method for the diagnosis and therapeutic control of Helicobacter-status.
Cloud-Based Control: A Multi-tenant, Horizontally Scalable Soft-PLC (2015)

In industrial automation, the control and operation of factories and plants in usually performed by Programmable Logic Controllers (PLCs). As automation tasks find their way into more and more smaller application areas where it is economically not reasonable to employ, engineer and maintain a full, hardware-based PLC, a cloud-based software PLC (Soft-PLC) can serve as a Control-as-a-Service solution. In this paper, we address the question how a Soft-PLC can be augmented with cloud-required aspects such as elastic scalability and multi-tenancy. We introduce an architecture that realizes these properties and allows for the implementation of a multi-tenant, horizontally scalable Soft-PLC. Furthermore, we evaluate the most important quality attributes, i.e. Roundtrip times and scalability of our architecture based on a prototypical implementation and a case study from the building automation domain. Finally, we present lessons learned and give an outlook to further realistic scenarios for cloud-based control in industrial applications.
High-Performance Liquid Chromatography for Determination of Adenosine-5'-Triphosphate in Biological Materials (1983)

A high-performance liquid chromatographic method for the determination of adenosine-5'-triphosphate (ATP) in the biological materials, blood, heart, liver and kidney is described. The organs were frozen in liquid nitrogen immediately after the removal in situ with precooled tongs and homogenized with cold 10% trichloroacetic acid and 0.1 N HCl. The chromatographic analysis utilized an anion exchange (Polygosil N (CH3)2) column with a mobile phase of 0.35 M KH2PO4 buffer (pH3.35) and ultraviolet monitoring at 260 nm. This method was applied to the determination of ATP in the blood, heart, liver and kidney. The minimum detectable quantity of ATP was 10 pmol (about 55 ng) and the coefficient of variation was about 1%.
Robot Indoor Navigation Using Visible Light Communication (2018)

The following topics are dealt with: history; information retrieval systems; Internet; art; humanities; data analysis; archaeology; geographic information systems; interactive systems; Web sites.
Mixing behavior of a dual-patch active antenna oscillator at 1.2 GHz (2005)

Active antennas have received attention in the literature for the size, weight, and cost improvements they allow. Of interest for communications purposes are self-oscillating mixer active antennas. These systems use a single active device to perform both oscillation and mixing functions. We report the significant mixing gain of a dual-patch active antenna oscillator based on a MMIC RF amplifier and operating at 1.2 GHz. The conversion gain depends on the supply voltage of the amplifier and the IF chosen. The present setup uses only four discrete components and could be used as the front-end for a simple FM receiver.
A Case Study on Establishing the Records Management System in the KDI School (2007)

This case study aims to describe the principles and methods of records management applied to the systematic management of records in the KDI School of Public Policy and Management, and the process of its practical implementation. It provides more extensive coverage than most existing studies on records management, dealing with all procedures from the theoretical modeling to the records management system building. The School has built the Records Center that can integratively manage its administrative records and archives that have been erratic and unsystematic over the years. As a result, the introduction of records management has become a basis for succeeding the achievements of the KDI School and its history as well as supporting administrative and knowledge resources. As well, it is intended to be a guide for other schools or institutions when building the records management system.