gebhart/patrepeval huggingface dataset:
Stresses in TaSi<i>x</i> films sputter deposited on polycrystalline silicon (1987)

Stress in thin TaSix films sputtered on polycrystalline silicon was studied as a function of temperature. A dual laser-beam apparatus was used to measure wafer curvature in situ. Stress was studied in the TaSi2/undoped polysilicon structure, in TaSi2 on polysilicon doped with either phosphorus, arsenic, or boron, and in films with a deposited Si/Ta ratio of more than 2. Several observations of stress-temperature behavior in TaSi2 were made. Tensile stress in TaSi2/undoped polysilicon increases to 1.2×1010 dyn/cm2 at 450 °C during the postdeposition anneal, decreases to near 0 at 900 °C, and linearly increases as temperature is subsequently lowered. Both doping and stoichiometry affected the stress-temperature behavior. N-type dopants decreased tensile stress and boron did not. Raising the Si/Ta ratio increased tensile stress at high temperatures. The stress-temperature measurements were combined with results from other characterization techniques to draw conclusions about the influence of temperature on the film. TaSi2 compound formation was found to occur at less than 400 °C in these films.
Involvement of the hepatocyte growth factor/scatter factor receptor c-met and of Bcl-xL in the resistance of oropharyngeal cancer to ionizing radiation (2001)

The activation of cytoplasmic signal transduction pathways by a number of growth factors and their tyrosine-kinase receptors, including hepatocyte growth factor/scatter factor (HGF/SF) and its receptor c-met, exerts an inhibitory influence on apoptosis induced by ionizing radiation in vitro. The clinical relevance of the aforementioned ligand-receptor pair, of Bcl-xL, which is targeted by HGF/SF/c-met signaling, and of Bcl-2, was assessed by evaluating their predictive and prognostic impact in a cohort of 97 patients with radically irradiated squamous cell cancers of the oropharynx. Immunohistochemical expression of c-met and Bcl-xL was correlated with decreased rates of complete remission of the primary tumor in both the univariate (c-met: P = 0.01; Bcl-xL: P = 0.001) and multivariate analyses. Expression of c-met was, moreover, a significant and independent predictor of impaired local failure-free survival (P = 0.003), disease-free survival (P = 0.003) and overall survival (p = 0.001). Bcl-2 expression was, on the other hand, associated with a favorable outcome, in terms of both local failure-free survival (P = 0.01) and overall survival (P = 0.001). In accordance with in vitro data, c-met and Bcl-xL appear to be involved in the resistance of oropharyngeal cancers to ionizing radiation, and may therefore represent attractive targets for radiosensitization.
The Truncated Region Eigenfunction Expansion Method for the Solution of Boundary Value Problems in Eddy Current Nondestructive Evaluation (2005)

A number of complex problems in eddy current nondestructive evaluation have been solved recently using the truncated region eigenfunction expansion method. The solution of a boundary value problem is commonly obtained by separation of variables. In a particular unbounded coordinate, the solution is usually expressed as an integral form such as a Fourier or Bessel integral. However, by truncating the domain of the problem, a modified solution is obtained in the form of a series expansion instead of an integral. Although one achieves a gain in computation efficiency in this way, the most significant advantage of the approach is the ability to match interface conditions across several boundaries simultaneously and thus obtain analytical solutions to complex problems. We illustrate the approach by solving the axisymmetric, time harmonic boundary value problem of a coil above a coaxial hole in a plate.
<title>Guided-wave optoelectronic clock-distribution networks on multichip modules using MEMS fabrication techniques</title> (1998)

This paper addresses the design, fabrication, and packaging issues of optoelectronic clock distribution networks on multichip modules (MCM) by combining guided-wave optoelectronic interconnect, MCM packaging, and microelectromechanical system fabrication techniques. The proposed prototype employs the silica glass waveguide networks on silicon substrates and innovative I/O coupling method which utilizes the micromachined through-holes across MCM substrates and silicon mirror arrays. Microstructures for I/O coupling have been fabricated using KOH etchants at various processing conditions and the silica glass optical waveguide networks are fabricated using FHD and RIE processes. The four fanout optoelectronic clock distribution networks are prototyped and characterized by measuring the overall insertion losses and the power equalities at the fanout nodes.
Structure elucidation of a new friedelane triterpene from the mangrove plant <i>Hibiscus tiliaceus</i> (2006)

From the stem and bark of the mangrove plant Hibiscus tiliaceus, a new friedelane-type triterpene named 27-oic-3-oxo-28-friedelanoic acid (1) together with eight known triterpenoids involving five friedelane-type derivatives was isolated. The structure of 1 was determined by extensive 2D NMR (DQF-COSY, HMQC, HMBC, and NOESY) data analyses. All the compounds were obtained from mangrove plants for the first time.
A large-scale multiple dielectric barrier discharge actuator based on an innovative three-electrode design (2009)

For about 10 years, surface dielectric barrier discharges (DBDs) have been widely used as plasma actuators in subsonic airflow control applications. However, the extension length of a single surface DBD is limited to about 2 cm, which could restrict its use to small-scale applications. One way to extend the plasma actuation surface consists of using several single surface DBDs in series, energized by zero phase delayed or phase shifted high voltages. However, the mutual interaction between successive discharges affects the benefits of such standard multi-DBD actuators. This paper deals with a new design electrode for large-scale flow control applications. It consists of replacing each single two-electrode DBD by a three-electrode DBD where the third electrode acts as a shield between two successive DBDs. Experimental measurements by laser doppler velocimetry, pressure probe and time-resolved particle image velocimetry show that the mutual interactions can be strongly reduced, resulting in a constant electric wind velocity above the multi-DBD actuator.
EĞİTİM YÖNETİMİNDE CHARTER MODELİ VE TÜRKİYE’DE UYGULANABİLİRLİĞİ (2013)

1990’lı yıllarda Amerika’da ortaya çıkan Charter eğitim modelinin yönetim yapısı, uygulanabilirliğinin ele alındığı çalışmanın amacı charter modelinin Türk eğitim sistemi bağlamında tartışmaya açılmasını sağlamaktır. Çalışmanın temel tezi charter modelinin Türk eğitim sisteminin içinde bulunduğu sorunların aşılmasına katkıda bulunabileceği, Türk eğitim yönetimine yeni aktörler katarak eğitim yönetimin daha demokratik hale gelmesine katkı yapabileceğidir. Charter modelinin Türkiye’ye bağlamında tartışılması, en azından eğitim sorunlarının sınav ve dershane ekseninden çıkarılıp farklı perspektifle tartışılmasına imkân sağlayabilir
Optimizing power normalization for G.fast linear precoder by linear programming (2014)

The use of vectoring for crosstalk cancellation in the new ITU-T G.fast standard for next generation DSL systems becomes essential for efficient utilization of the extended bandwidth (up to 200 MHz). In VDSL2 (up to 30 MHz), a zero-forcing-based linear precoder is used in downstream which approaches single-line performance. However, at high frequencies, the linear precoder may amplify the signal power substantially since the crosstalk channel is much stronger than at lower frequencies. Performance could be significantly degraded by power normalization to keep the PSD below the mask. In this work, we extended a per-line power normalization scheme by linear programming (LP) optimization. By simulations using measured cable data it is shown how the LP-based scheme further improves the linear precoder and it is also capable of balancing the data rate between lines. Further, the simulations also show the non-linear Tomlinson-Harashima precoder performs better than the linear precoders.
Dietary Oils with Added Tocopherols: Effects on Egg or Tissue Tocopherols, Fatty Acids, and Oxidative Stability (1996)

The effect of dietary oils [menhaden (MO), flax (FL), palm (PO), and sunflower oils (SF)] with added tocopherols on the tocopherol deposition, fatty acid composition, and thiobarbituric acid (TBA) values of egg or tissues (liver, adipose tissue, white meat, and dark meat) were examined. Addition of tocopherols increased (P < 0.05) the total egg or tissue tocopherol content. The enhancement of total tocopherols in the different tissues in the order of magnitude were egg yolk > liver > adipose tissue > dark meat > white meat. Dark meat contained higher (P < 0.05) total tocopherols than white meat. Dietary MO or FL resulted in a significant (P < 0.05) incorporation of C20:5 n-3 and C22:6 n-3 with a concomitant reduction in C20:4 n-6 in liver, egg, white meat, and dark meat. Dietary SF resulted in a significant (P < 0.05) incorporation of C18:2 n-6 and C20:4 n-6 in all the tissues. Addition of PO did not result in any change in the yolk saturated fatty acid content. The content of monounsaturated fatty acids were greater (P < 0.05) in all the tissues from PO diets than in diets with other oils. Dietary tocopherols resulted in a significant increase (P < 0.05) in the content of C20:5 n-3 and C22:6 n-3 in the yolk, adipose tissue, and white meat from birds fed MO + T diets. Inclusion of tocopherols resulted in a significant (P < 0.05) reduction in TBA values in eggs, in liver for MO and FL diets, and in dark and white meat for the MO diet. Tocopherol supplementation did not result in any change in TBA values in the PO diet.
A ten-year review of commercial vaccine performance for control of tick infestations on cattle (2007)

Ticks are important ectoparasites of domestic and wild animals, and tick infestations economically impact cattle production worldwide. Control of cattle tick infestations has been primarily by application of acaricides which has resulted in selection of resistant ticks and environmental pollution. Herein we discuss data from tick vaccine application in Australia, Cuba, Mexico and other Latin American countries. Commercial tick vaccines for cattle based on the Boophilus microplus Bm86 gut antigen have proven to be a feasible tick control method that offers a cost-effective, environmentally friendly alternative to the use of acaricides. Commercial tick vaccines reduced tick infestations on cattle and the intensity of acaricide usage, as well as increasing animal production and reducing transmission of some tick-borne pathogens. Although commercialization of tick vaccines has been difficult owing to previous constraints of antigen discovery, the expense of testing vaccines in cattle, and company restructuring, the success of these vaccines over the past decade has clearly demonstrated their potential as an improved method of tick control for cattle. Development of improved vaccines in the future will be greatly enhanced by new and efficient molecular technologies for antigen discovery and the urgent need for a tick control method to reduce or replace the use of acaricides, especially in regions where extensive tick resistance has occurred.
Aberrant syntheses in higher plants. 4. Aberrant biosynthesis of 5-fluoroanabasine from 5-fluoro[5,6-14C,13C2]nicotinic acid, established by means of carbon-13 nuclear magnetic resonance (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAberrant syntheses in higher plants. 4. Aberrant biosynthesis of 5-fluoroanabasine from 5-fluoro[5,6-14C,13C2]nicotinic acid, established by means of carbon-13 nuclear magnetic resonanceEdward LeeteCite this: J. Org. Chem. 1979, 44, 2, 165–168Publication Date (Print):January 1, 1979Publication History Published online1 May 2002Published inissue 1 January 1979https://pubs.acs.org/doi/10.1021/jo01316a001https://doi.org/10.1021/jo01316a001research-articleACS PublicationsRequest reuse permissionsArticle Views98Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluación de la efectividad biológica de Cryptolaemus Montrouzieri Mulsant en áreas afectadas por Maconellicoccus Hirsutus (Green) en Cienfuegos (2016)

La presente investigacion ha sido desarrollada en el laboratorio provincial de Sanidad Vegetal de Cienfuegos y se propone el objetivo de evaluar la efectividad biologica de Cryptolaemus montrouzieri Mulsant, en areas donde se detecta Maconellicoccus hirsutus (Green) (Hemiptera: Pseudococcidae), durante el periodo comprendido entre agosto de 2014 hasta mayo de 2015. Para lo que se realizan liberaciones de adultos del biorregulador. Se opera con el metodo de aplicar dosis inundativas, se emplea como base la metodologia de reproduccion propuesta por el Instituto Nacional de Sanidad Vegetal que sugiere esta aplicacion si los niveles de poblaciones de plagas son altos. Se evalua la efectividad biologica de acuerdo con la formula de Abbott modificada. Mediante las aplicaciones de C. montrouzierise se han logrado efectividades tecnicas entre el 5,0 y el 99,9 %. El mejor control de la plaga, con una efectividad de 81,0-99,9 se logra en zonas donde hay baja o poca accion antropomorfica.Palabras clave:Biorregulador, biocontrol, ninfas. ABSTRACTThis research was carried out at the Cienfuegos Provincial Plant Health Laboratory and is aimed at evaluating the biological effectiveness of Cryptolaemus montrouzieri Mulsant in areas where Maconellicoccus hirsutus (Green) (Hemiptera: Pseudococcidae) was detected during the period from August 2014 to May 2015. For this bioregulator adult releases were made. The method of applying inundative doses is used, based on the reproduction methodology proposed by the National Institute of Plant Protection which suggests this application if plague population level is high. Biological effectiveness is evaluated according to the modified Abbot formula. With the application of C. montrouzierise technical effectiveness between 5.0 and 99.9 % have been achieved. The best plague control, with an effectiveness of 81,0-99,9, is achieved in zones where there is low anthropomorphic action.Keywords: Bioregulator, biocontrol, nymphs
High management impact of Ga‐68 DOTATATE (GaTate) PET/CT for imaging neuroendocrine and other somatostatin expressing tumours (2012)

GaTate PET/CT imaging provides additional diagnostic information in a high proportion of patients with consequent high management impact. GaTate PET/CT could replace (1)In-111 octreotide scintigraphy at centres where it is available given its superior accuracy, faster acquisition and lower radiation exposure. Rapid implementation could be achieved by allowing substitutional funding in the Medicare Benefit Schedule.
New Synthetic Method of Alkyl Perfluoroalkyl Ethers (2000)

vic-Difluorination of alkyl perfluoroenol ethers proceeded with high-valence metal fluoride, such as cobalt(III) fluoride and potassium tetrafluorocobaltate, in good yields to afford alkyl perfluoroalkyl ethers.
Effect of localization of missense mutations in <i>SCN1A</i> on epilepsy phenotype severity (2004)

There was a significant phenotype-genotype relationship in generalized epilepsy with febrile seizures plus and severe myoclonic epilepsy of infancy with SCN1A missense mutations. More severe sodium channel dysfunctions including abnormal ion selectivity that are caused by mutations in the pore regions may be involved in the pathogenesis of SMEI.
Strategies for developing NADH detector based on meldola blue in different immobilization methods: a comparative study (2006)

Foi realizado um estudo comparativo entre duas metodologias de imobilizao do Azul de Meldola (MB), utilizado para diminuir o potencial de oxidao do NADH. O estudo foi realizado no eletrodo de carbono vtreo atravs da eletropolimerizao do pirrol e MB, empregando a tcnica de voltametria cclica e avaliando-se o efeito do nmero de ciclos para definir a espessura e a estabilidade do filme. Com 25 ciclos foi obtido o melhor resultado. Foi tambm investigada a modificao do eletrodo de grafite com filme formado pelo sistema sol-gel PPO 300 ou PPO 4000 pelo mtodo de recobrimento por mergulho, atravs de dois mtodos: ocluso e adsoro. O melhor mtodo foi o de adsoro da MB durante 10 min, seguida de depsito do filme PPO 300, favorecido pelo tempo de secagem (24 horas). A adsoro da MB seguido do depsito do PPO 300 apresentou maior intervalo linear do que a metodologia do PPY.
TESSERACT: Eliminating Experimental Bias in Malware Classification across Space and Time (2018)

Is Android malware classification a solved problem? Published F1 scores of up to 0.99 appear to leave very little room for improvement. In this paper, we argue that results are commonly inflated due to two pervasive sources of experimental bias: "spatial bias" caused by distributions of training and testing data that are not representative of a real-world deployment; and "temporal bias" caused by incorrect time splits of training and testing sets, leading to impossible configurations. We propose a set of space and time constraints for experiment design that eliminates both sources of bias. We introduce a new metric that summarizes the expected robustness of a classifier in a real-world setting, and we present an algorithm to tune its performance. Finally, we demonstrate how this allows us to evaluate mitigation strategies for time decay such as active learning. We have implemented our solutions in TESSERACT, an open source evaluation framework for comparing malware classifiers in a realistic setting. We used TESSERACT to evaluate three Android malware classifiers from the literature on a dataset of 129K applications spanning over three years. Our evaluation confirms that earlier published results are biased, while also revealing counter-intuitive performance and showing that appropriate tuning can lead to significant improvements.
Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic acid animal model of autism (2008)

The prefrontal cortex has been extensively implicated in autism to explain deficits in executive and other higher-order functions related to cognition, language, sociability and emotion. The possible changes at the level of the neuronal microcircuit are however not known. We studied microcircuit alterations in the prefrontal cortex in the valproic acid rat model of autism and found that the layer 5 pyramidal neurons are connected to significantly more neighbouring neurons than in controls. These excitatory connections are more plastic displaying enhanced long-term potentiation of the strength of synapses. The microcircuit alterations found in the prefrontal cortex are therefore similar to the alterations previously found in the somatosensory cortex. Hyper-connectivity and hyper-plasticity in the prefrontal cortex implies hyper-functionality of one of the highest order processing regions in the brain, and stands in contrast to the hypo-functionality that is normally proposed in this region to explain some of the autistic symptoms. We propose that a number of deficits in autism such as sociability, attention, multi-tasking and repetitive behaviours, should be re-interpreted in the light of a hyper-functional prefrontal cortex.
Low-loss and misalignment-tolerant fiber-to-chip edge coupler based on double-tip inverse tapers (2016)

A novel fiber-to-chip edge coupler with two tapered tips and a multimode interference combiner is demonstrated on a silicon-on-insulator platform. It has advantages over a single-tip edge coupler on coupling loss, bandwidth and misalignment tolerance.
Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis. (2003)

Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.
Lipid content of cured tobacco (1974)

Samples from cured burley and flue-cured tobacco were examined for total lipid content and for lipid composition of fractionated lipid classes. Cured burley tobacco contained 6–8% lipids compared with 14–15% in cured flue-cured tobacco. Neutral lipids constituted 70–80% of burley lipids but only half the flue-cured lipids; the latter had 75% more neutral lipids than the former. Flue-cured tobacco contained considerably more (5–10 times) medium- to high-polarity lipids than burley. Stalk position had only a minor effect on the lipid content of both tobacco types.
Omics-based identification of <i>Arabidopsis</i> Myb transcription factors regulating aliphatic glucosinolate biosynthesis (2007)

Understanding plant metabolism as an integrated system is essential for metabolic engineering aimed at the effective production of compounds useful to human life and the global environment. The "omics" approach integrates transcriptome and metabolome data into a single data set and can lead to the identification of unknown genes and their regulatory networks involved in metabolic pathways of interest. One of the intriguing, although poorly described metabolic pathways in plants is the biosynthesis of glucosinolates (GSLs), a group of bioactive secondary products derived from amino acids that are found in the family Brassicaceae. Here we report the discovery of two R2R3-Myb transcription factors that positively control the biosynthesis of GSLs in Arabidopsis thaliana by an integrated omics approach. Combined transcriptome coexpression analysis of publicly available, condition-independent data and the condition-specific (i.e., sulfur-deficiency) data identified Myb28 and Myb29 as candidate transcription factor genes specifically involved in the regulation of aliphatic GSL production. Analysis of a knockout mutant and ectopic expression of the gene demonstrated that Myb28 is a positive regulator for basal-level production of aliphatic GSLs. Myb29 presumably plays an accessory function for methyl jasmonate-mediated induction of a set of aliphatic GSL biosynthetic genes. Overexpression of Myb28 in Arabidopsis-cultured suspension cells, which do not normally synthesize GSLs, resulted in the production of large amounts of GSLs, suggesting the possibility of efficient industrial production of GSLs by manipulation of these transcription factors. A working model for regulation of GSL production involving these genes, renamed Production of Methionine-Derived Glucosinolate (PMG) 1 and 2, are postulated.