gebhart/patrepeval huggingface dataset:
Public key infrastructures and digital certificates for the Internet of things (2015)

The exponential growth of connected autonomous embedded devices (aka the IoT) will pose huge challenges with regard to device- and inter-device communication security. Features like encrypted communication, device authentication and device authorisation must be appropriately addressed in order to provide a reliable and penetration-resistant device network. However, recent examples of cyber-attacks on such networks and the current lack of generic standards have shown that there is still a long way to go. Public key infrastructures (PKI) and digital certificates are key elements of today's secure Internet infrastructure. This paper analyses the benefits, limitations and suitability of both concepts for IoT deployments in combination with secure communication protocols. Based on this assessment it proposes an adopted PKI architecture that provides and manages customised X.509 digital certificates.
Combined Blockade of Src Kinase and Epidermal Growth Factor Receptor with Gemcitabine Overcomes STAT3-Mediated Resistance of Inhibition of Pancreatic Tumor Growth (2011)

These results provide evidence that combined targeted biological therapy in addition to cytotoxic chemotherapy can overcome treatment resistance. Such treatment strategies may be used to tailor therapy based on identified biomarkers of resistance to targeted monotherapy.
Neither more nor less: optimizing thread-level parallelism for GPGPUs (2013)

General-purpose graphics processing units (GPGPUs) are at their best in accelerating computation by exploiting abundant thread-level parallelism (TLP) offered by many classes of HPC applications. To facilitate such high TLP, emerging programming models like CUDA and OpenCL allow programmers to create work abstractions in terms of smaller work units, called cooperative thread arrays (CTAs). CTAs are groups of threads and can be executed in any order, thereby providing ample opportunities for TLP. The state-of-the-art GPGPU schedulers allocate maximum possible CTAs per-core (limited by available on-chip resources) to enhance performance by exploiting TLP. However, we demonstrate in this paper that executing the maximum possible number of CTAs on a core is not always the optimal choice from the performance perspective. High number of concurrently executing threads might cause more memory requests to be issued, and create contention in the caches, network and memory, leading to long stalls at the cores. To reduce resource contention, we propose a dynamic CTA scheduling mechanism, called DYNCTA, which modulates the TLP by allocating optimal number of CTAs, based on application characteristics. To minimize resource contention, DYNCTA allocates fewer CTAs for applications suffering from high contention in the memory sub-system, compared to applications demonstrating high throughput. Simulation results on a 30-core GPGPU platform with 31 applications show that the proposed CTA scheduler provides 28% average improvement in performance compared to the existing CTA scheduler.
New Fully Soft-Switched Boost-Converter with Reduced Conduction Losses (2006)

A new fully soft-switched boost-converter is proposed here, using only one auxiliary switch. All switches used in this converter turn on and turn off under fully soft-switched condition. The diodes also commutate softly. The converter uses minimum number of components in the auxiliary circuit without additional current stress of the main switch. The circuit conduction losses are also minimised, since the resonant capacitor charging current flows only through an inductor and a diode. The main and auxiliary IGBT share a common emitter connection, facilitating direct drive to them. The circuit is suitable for application to active power factor correction. Various operating modes of the converter are presented and analysed. The principle of operation has been verified with computer simulation and experimental results.
Model-based Processing of Micro-cantilever Sensor Arrays (2004)

We develop a model-based processor (MBP) for a micro-cantilever array sensor to detect target species in solution. After discussing the generalized framework for this problem, we develop the specific model used in this study. We perform a proof-of-concept experiment, fit the model parameters to the measured data and use them to develop a Gauss-Markov simulation. We then investigate two cases of interest: (1) averaged deflection data, and (2) multi-channel data. In both cases the evaluation proceeds by first performing a model-based parameter estimation to extract the model parameters, next performing a Gauss-Markov simulation, designing the optimal MBP and finally applying it to measured experimental data. The simulation is used to evaluate the performance of the MBP in the multi-channel case and compare it to a ''smoother'' (''averager'') typically used in this application. It was shown that the MBP not only provides a significant gain ({approx} 80dB) in signal-to-noise ratio (SNR), but also consistently outperforms the smoother by 40-60 dB. Finally, we apply the processor to the smoothed experimental data and demonstrate its capability for chemical detection. The MBP performs quite well, though it includes a correctable systematic bias error. The project's primary accomplishment was the successful application of model-based processing to signals from micro-cantilever arrays: 40-60 dB improvement vs. the smoother algorithm was demonstrated. This result was achieved through the development of appropriate mathematical descriptions for the chemical and mechanical phenomena, and incorporation of these descriptions directly into the model-based signal processor. A significant challenge was the development of the framework which would maximize the usefulness of the signal processing algorithms while ensuring the accuracy of the mathematical description of the chemical-mechanical signal. Experimentally, the difficulty was to identify and characterize the non-target signals present in the measurement system. In the future, these signals will limit the ability of the sensor to detect very small quantities of chemicals generated by nuclear processing. In this project, it became necessary to make use of a model system, mercaptoethanol, which created a large, reproducible signal that could be readily analyzed with the model-based processor. Further, redundant cantilevers were examined exclusively: all levers were nominally identically functionalized, and no ''control'' levers were used that did not react to the mercaptoethanol signal. To demonstrate the full utility of the MBP for chemical sensing, the logical and necessary next steps are (1) verify the physical models used in this study for a variety of solvents and target molecules (this data has already been obtained as part of this study) (2) make use of control levers, and (3) extend the experimental library to include low concentrations of chemical targets of practical interest for sensing nuclear processes.
Ribosomal Inhibitory Proteins from Plants Inhibit HIV-1 Replication in Acutely Infected Peripheral Blood Mononuclear Cells (1991)

Peripheral blood mononuclear cells from seronegative donors were stimulated with phytohemagglutinin and then infected with human immunodeficiency virus (HIV-1). Using this experimental system, the antiviral activity of two translation inhibitory proteins (pokeweed antiviral protein, PAP-S, and Luffa ribosomal inhibitory protein, LRIP-I) isolated from plants and a recombinant form of ricin A chain were studied. Previously, it had been shown that toxin polypeptides linked to monoclonal antibodies could inhibit HIV-infected cells. In the present study, the free, unconjugated, proteins were found to inhibit HIV replication at doses in which they were nontoxic to uninfected peripheral blood mononuclear cells. Among the inhibitory proteins, PAP-S and recombinant ricin A chain markedly reduced the reverse transcriptase activity and the expression of p24 core protein in infected cultures. Dose response studies indicate that the anti-HIV activity of PAP-S was comparable to AZT. The other ribosome inhibitory proteins (RIPs) showed moderate but significant antiviral activity.
Foot Growth Rate in Children Age One to Six Years (1983)

Previous guidelines suggested that children age 2 to 6 years require a shoe size change every 1 to 2 months. Our study of foot growth in 112 children enrolled in a prospective treatment protocol for flatfoot demonstrates that children age 12 to 30 months will require shoe size change every two to three months but that foot growth slows over the subsequent four years, necessitating shoe size change only every 4 months in children up to 4 years of age and every 6 months in children from age 4 to 6 years.
Total reflection x-ray fluorescence analysis of planarized semiconductor product wafers (1996)

The use and effectiveness of total reflection x-ray fluorescence (TXRF) have been widely reported. The application of this technique in semiconductor fabrication has become popular and several instrument vendors now make equipment optimized for this particular purpose. Because sample surfaces must be optically flat in order to achieve the total reflectance condition, the majority of the work in investigating semiconductor processing is performed on monitor wafers. The use of TXRF for in-line process control, therefore, has been limited to silicon or dielectric film substrates, either on the surface or the backside of the wafer. This article details the use of TXRF analysis for monitoring the contamination present on production-wafer surfaces, after planarization techniques have been used. The wafer surfaces at several of these planarization steps meet the criteria for the application of the TXRF technique using the normal operating conditions of the TXRF instrument. This technique can be used as process-monitoring tool to study wafer surfaces for particular contaminants that affect wafer yield. TXRF is being used on IBM’s state-of-the-art DRAM and logic circuits.
Combining Appearance and Structure from Motion Features for Road Scene Understanding (2009)

In this paper we present a framework for pixel-wise object segmentation of road scenes that combines motion and appearance features.It is designed to handle street-level imagery such as that on Google Street View and Microsoft Bing Maps.We formulate the problem in a CRF framework in order to probabilistically model the label likelihoods and the a priori knowledge.An extended set of appearance-based features is used, which consists of textons, colour, location and HOG descriptors.A novel boosting approach is then applied to combine the motion and appearance-based features.We also incorporate higher order potentials in our CRF model, which produce segmentations with precise object boundaries.We evaluate our method both quantitatively and qualitatively on the challenging Cambridge-driving Labeled Video dataset.Our approach shows an overall recognition accuracy of 84% compared to the state-of-the-art accuracy of 69%.
Photochromic sculpture (2011)

In contrast to light-emitting displays like plasma display panels (PDPs) and liquid crystal displays (LCDs), color-forming displays like "E-Ink" which displays information by reflecting surrounding light are being actively researched as a technology that is easy on the eye and can even be applied in bright places such as outdoors in sunlight. Applying photochromic materials (PM) for controlling color in this manner, Photochromic Canvas [Hashida et al. 2010] and Slow Display [Saakes et al. 2010], which are combined with projected-light systems, make it possible to control color without contact with the surface of an object. In this paper, the concept, namely, "contactless color control," is extended to volumetric space, and "volumetric color-forming pixels" are successfully created. This paper proposes a system referred to as "photochromic sculpture" which can generate a dynamically changeable 3D sculpture. (see Figure 1).
The ‘New’ Monetary Arrangements (1983)

The new arrangements for monetary control, which took effect from 20 August 1981, were set out in the Bank’s paper entitled ‘Monetary control — provisions’ (BEQB, September 1981, p.347) and followed discussions on two of their earlier documents: ‘Background note on methods of monetary control’ (BEQB, December 1980, p.428) and ‘Monetary control: next steps’ (BEQB, March 1981, p.38). The main proposals were:
Ion beam processing for coating MgF_2 onto ambient temperature substrates (1984)

In this paper, we report on the use of inert gas ion bombardment during the deposition of MgF2 films on ambient temperature substrates. The low energy (<250-eV/ion) bombardment is shown to increase significantly the abrasion resistance and adherence of the films without significantly degrading their optical performance. The success of this technique has wide-ranging implications for the application of durable coatings to temperature sensitive substrates.
RISK FACTORS FOR PRIMARY DYSFUNCTION AFTER LIVER TRANSPLANTATION—A MULTIVARIATE ANALYSIS (1993)

In a retrospective analysis on 323 orthotopic liver transplant procedures performed between July 1984 and October 1991 the incidence of two forms of primary dysfunction (PDF) of the liver: primary nonfunction (PNF), and initial poor function (IPF) were studied. The incidence of PDF was 22% (73/323) with 6% PNF (20/323) and 16% IPF (53/323), while 78% (250/323) had immediate function (IF). Occurrence of both IPF and PNF resulted in a higher graft failure rate (P < 0.001), retransplantation rate (P < 0.001), and patient mortality (P < 0.003) within the first three months after OLTx. Univariate analyses of donor and recipient factors and their influence on PDF demonstrated that longer donor hospitalization (> 3 days), older donor age (> 49 years), extended preservation times (> 18 hr), and fatty changes in the donor liver biopsy, as well as reduced-size livers, younger recipient age, and renal insufficiency prior to OLTx, significantly affected the incidence of IPF and PNF. Multivariate analysis of potential risk factors showed that reduced-size liver (P = 0.0001), fatty changes on donor liver biopsy (P = 0.001), older donor age (P = 0.009), retransplantation (P = 0.01), renal insufficiency (P = 0.02), and prolonged cold ischemia times (P = 0.02) were independently associated with a higher incidence of IPF and PNF. No statistical correlation was found between PDF and etiology of ESLD, nutritional status of the recipient, UNOS status, and Child-Pugh classification in this study. We conclude that PNF and IPF are both separate clinical entities that have a significant effect on outcome after OLTx. Routine donor liver biopsies are recommended to decrease the rate of IPF and PNF. The combination of risk factors shown to be significant for PDF should be avoided--and, if that is not possible, the only variable that can be controlled, the preservation time, should be kept as short as possible.
Human Cytomegalovirus-Encoded G Protein-Coupled Receptor US28 Mediates Smooth Muscle Cell Migration through Gα12 (2004)

Coupling of G proteins to ligand-engaged chemokine receptors is the paramount event in G-protein-coupled receptor signal transduction. Previously, we have demonstrated that the human cytomegalovirus-encoded chemokine receptor US28 mediates human vascular smooth muscle cell (SMC) migration in response to either RANTES or monocyte chemoattractant protein 1. In this report, we identify the G proteins that couple with US28 to promote vascular SMC migration and identify other signaling molecules that play critical roles in this process. US28-mediated cellular migration was enhanced with the expression of the G-protein subunits Galpha12 and Galpha13, suggesting that US28 may functionally couple to these G proteins. In correlation with this observation, US28 was able to activate RhoA, a downstream effector of Galpha12 and Galpha13 in cell types with these G proteins but not in those without them and activation of RhoA was dependent on US28 stimulation with RANTES. In addition, inactivation of RhoA or the RhoA-associated kinase p160ROCK with a dominant-negative mutant of RhoA or the small molecule inhibitor Y27632, respectively, abrogated US28-induced SMC migration. The data presented here suggest that US28 functionally signals through Galpha12 family G proteins and RhoA in a ligand-dependent manner and these signaling molecules are important for the ability of US28 to induce cellular migration.
Análise de Sentimento para Reviews Apresentados em Vídeos: Modelo de Redes Neurais Treinado em Base de Reviews Escritos/ Sentiment Analysis for Reviews Featured in Videos: Neural Network Model Trained on Written Reviews Database (2021)

A análise de sentimentos tem sido apresentada como uma técnica importante para avaliação de reviews em grandes volumes de dados disponibilizados nas redes sociais. Este trabalho apresenta uma abordagem de busca dos textos a partir de transcrições de vídeos disponibilizados sobre reviews de smartphones e aplica a análise de sentimentos neste context a partir do treinamento de modelo de Redes Neurais Convolutivas em uma base de dados com 10.063.255 reviews escritos de um site de compras online e avaliado o seu desempenho em classificações dos trechos de reviews classificados manualmente pelos pesquisados. Como resultado, conclui-se que o aproveitamento do padrão textual observado em uma base de dados de reviews escritos pode trazer resultados positivos mesmo aplicado em um padrão diferente e que não esteja disponível ou classificada para uma tarefa de aprendizado supervisionado.
Isoflurane and Desflurane Uptake During Liver Resection and Transplantation (2003)

When reducing fresh gas flows, the course of the vaporizer dial settings required to maintain a constant end-expired concentration of a potent inhaled anesthetic becomes more dependent on the uptake pattern of the inhaled anesthetic. However, the uptake pattern of potent inhaled anesthetics during prolonged procedures remains poorly quantified. Therefore, we determined isoflurane and desflurane uptake (Viso and Vdes, respectively) during liver resection (LR, n = 17) and orthotopic liver transplantation (OLT, n = 18) using a liquid injection closed-circuit anesthesia technique maintaining the end-expired concentration at 0.8% and 4.5%, respectively. Individual and average uptake curves were fit to a series of mathematical functions and compared with the square root of time and four-compartment models. Cumulative doses of isoflurane and desflurane after 1 and 3 h in the LR group and after 1, 3, and 8 h in the OLT group were correlated with demographic variables and each patient’s average cardiac output and cardiac index. Average uptake was best described by a biexponential fit: Viso (LR) = 1.5 × (1 − e−t × 0.525) + 16.4 × (1 − e−t × 0.00506) (R2 = 0.9996); Viso (OLT) = 1.4 + 3.1 × (1 − e−t × 0.472) + 26.7 × (1 − e−t × 0.00307) (R2 = 0.9994); Vdes (LR) = 2.7 × (1 − e−t × 0.763) + 28.7 × (1 − e−t × 0.00568) (R2 = 0.9984); and Vdes (OLT) = 1.4 × (1 − e−t × 0.472) + 26.7 × (1 − e−t × 0.00307) (R2 = 0.9994). Uptake showed significant interindividual variability, and correlations between uptake variables and patient characteristics were inconsistent. The rate of uptake decreased more slowly then predicted by the uptake models. Because neither existing models nor patient characteristics accurately predict uptake in the individual patient, anesthesia techniques involving the use of low fresh gas flows will continue to have to rely on drug monitoring. However, the slowly decreasing rate of uptake during prolonged procedures suggests that the number of vaporizer adjustments to keep the end-expired concentration constant should be limited.
Origin of Androgen-Insensitive Poorly Differentiated Tumors in the Transgenic Adenocarcinoma of Mouse Prostate Model (2007)

Following castration, the transgenic adenocarcinoma of mouse prostate (TRAMP) model demonstrates rapid development of SV40-Tag-driven poorly differentiated tumors that express neuroendocrine cell markers. The cell population dynamics within the prostates of castrated TRAMP mice were characterized by analyzing the incorporation of 5-bromodeoxyuridine (BrdUrd) and the expression of SV40-Tag, synaptophysin, and androgen receptor (AR). Fourteen days postcastration, the remaining epithelial cells and adenocarcinoma cells were nonproliferative and lacked detectable SV40-Tag or synaptophysin expression. In contrast, morphologically distinct intraglandular foci were identified which expressed SV40-Tag, synaptophysin, and Ki67, but that lacked AR expression. These proliferative SV40-Tag and synaptophysin-expressing intraglandular foci were associated with the rare BrdUrd-retaining cells. These foci expanded rapidly in the postcastration prostate environment, in contrast to the AR- and SV40-Tag-expressing adenocarcinoma cells that lost SV40-Tag expression and underwent apoptosis after castration. Intraglandular foci of synaptophysin-expressing cells were also observed in the prostates of intact TRAMP mice at a comparable frequency; however, they did not progress to rapidly expanding tumors until much later in the life of the mice. This suggests that the foci of neuroendocrine-like cells that express SV40-Tag and synaptophysin, but lack AR, arise independent of androgen-deprivation and represent the source of the poorly differentiated tumors that are the lethal phenotype in the TRAMP model.
Influence of surface adsorption in improving ultrashallow junction formation (2006)

The continual downscaling of silicon devices for integrated circuits requires the formation of transistor (p-n) junctions that are progressively shallower yet incorporate increasing levels of electrically active dopant. In the case of implanted arsenic, the authors show that both goals can be accomplished simultaneously and controllably through the adsorption of small amounts of atomic nitrogen on the Si(100) surface.
Automation of pollen analysis using a computer microscope : a thesis presented in partial fulfilment of the requirements for the degree of Master of Engineering in Computer Systems Engineering at Massey University (2004)

The classification and counting of pollen is an important tool in the understanding of processes in agriculture, forestry, medicine and ecology. Current pollen analysis methods are manual, require expert operators, and are time consuming. Significant research has been carried out into the automation of pollen analysis, however that work has mostly been limited to the classification of pollen. This thesis considers the problem of automating the classification and counting of pollen from the image capture stage. Current pollen analysis methods use expensive and bulky conventional optical microscopes. Using a solid-state image sensor instead of the human eye removes many of the constraints on the design of an optical microscope. Initially the goal was to develop a single lens microscope for imaging pollen. In-depth investigation and experimentation has shown that this is not possible. Instead a computer microscope has been developed which uses only a standard microscope objective and an image sensor to image pollen. The prototype computer microscope produces images of comparable quality to an expensive compound microscope at a tenth of the cost. A segmentation system has been developed for transforming images of a pollen slide, which contain both pollen and detritus, into images of individual pollen suitable for classification. The segmentation system uses adaptive thresholds and edge detection to isolate the pollen in the images. The automated pollen analysis system illustrated in this thesis has been used to capture and analyse four pollen taxa with a 96% success rate in identification. Since the image capture and segmentation stages described here do not affect the classification stage it is anticipated that the system is capable of classifying 16 pollen taxa, as demonstrated in earlier research.
全科医学中的心理健康病案研究（一）——惊恐发作 (2012)

中国全科医学杂志与澳大利亚Monash大学共同合作创建了JohnMurtagh全科病案研究专栏，深受广大读者的欢迎。2012年伊始，我刊与澳大利亚的全科医学专家和心理学专家共同推出“全科医学中的心理健康病案研究”学术专栏。这个新专栏的诞生，是为了响应人民日益增长的心理健康服务需要，通过对心理问题病案的研究和分析，提高中国全科医学工作者和研究者对居民心理问题重要性的认识，提高其对心理问题的识别、治疗技术和技巧。