gebhart/patrepeval huggingface dataset:
Chemical Fixation of Enzymes to Cyanogen Halide Activated Polysaccharide Carriers (1971)

Water‐insolubel chymotrypsin, trypsin and papain have been synthesized by covalent fixation of the enzymes to beads of cross‐linked dextran (Sephadex ® ), beads of agarose, and cellulose powder. The fixation procedure involves two simple steps: (a) activation of the polysaccharide polymer by a cyanogen halide; (b) coupling of the protein to the activated polymer in slighly alkaline medium. The activation process can be controlled so as to retain certain useful or essential properties of the carrier material, such as particle shape and swelling capacity. The enzyme conjugates of Sephadex and agarose are therefore especialy suitable for use in the column format. The coupling process is so mild that a large portion of the inherent enzymic activity is conserved. However, the steric properties and other features of the carrier framework often prevents full manifestatuion of the fixed activity. Catalysts that are highly efficient toward small substrates are easily obtainable. Teh agarose‐bound enzymes can even exhibit high activities toward large proteins. Conjugates of the latter type should therefore be particularly useful for the digestion of prtoeins.
Synthesis of IPN polymer hybrids of polystyrene gel and silica gel by an in-situ radical polymerization method (1998)

Homogeneous IPN polymer hybrids of polystyrene gel and silica gel were prepared by applying an in-situ polymerization method to styrene monomer and divinylbenzene. The monomers were mixed in the sol–gel reaction mixture of tetramethoxysilane and subjected to radical polymerization, resulting in transparent glassy materials. The homogeneity was confirmed by nitrogen porosimetry methods. The organic part was found to be dispersed at the nanometer scale. The obtained IPN polymer hybrids are highly solvent resistant.
Cloning and expression of new microRNAs from zebrafish (2006)

MicroRNAs (miRNAs) play an important role in development and regulate the expression of many animal genes by post-transcriptional gene silencing. Here we describe the cloning and expression of new miRNAs from zebrafish. By high-throughput sequencing of small-RNA cDNA libraries from 5-day-old zebrafish larvae and adult zebrafish brain we found 139 known miRNAs and 66 new miRNAs. For 65 known miRNAs and for 11 new miRNAs we also cloned the miRNA star sequence. We analyzed the temporal and spatial expression patterns for 35 new miRNAs and for 32 known miRNAs in the zebrafish by whole mount in situ hybridization and northern blotting. Overall, 23 of the 35 new miRNAs and 30 of the 32 known miRNAs could be detected. We found that most miRNAs were expressed during later stages of development. Some were expressed ubiquitously, but many of the miRNAs were expressed in a tissue-specific manner. Most newly discovered miRNAs have low expression levels and are less conserved in other vertebrate species. Our cloning and expression analysis indicates that most abundant and conserved miRNAs in zebrafish are now known.
Substitutions électrophiles en série naphtalénique. IV. Sur le diméthyl-2,6 naphtalène (1968)

not available
First-row transition metal dichalcogenide catalysts for hydrogen evolution reaction (2013)

A group of first-row transition metal dichalcogenides (ME2, M = Fe, Co, Ni; E = S, Se) are introduced as non-precious HER catalysts in an acidic electrolyte. They exhibit excellent catalytic activity especially in their nanoparticle form. These compounds expand and enrich the family of high performance HER catalysts.
Reduction of Sulfur Dioxide by Methane to Elemental Sulfur over Supported Cobalt Catalysts (1997)

Cobalt oxides supported on several types of carriers (silica, molecular sieves 5A and 13X, and γ-Al2O3) were evaluated for the reduction of sulfur dioxide by methane to elemental sulfur. Results showed that γ-Al2O3 is the most effective carrier and that, with a molar ratio of 2 to 1 of sulfur dioxide to methane in a feed gas, the sulfur yield reached a maximum value of 87.5% at a space velocity of 5000 h-1 and a temperature of 840 °C. X-ray diffraction results revealed that mixtures of cobalt oxide and cobalt sulfide components were observed. The effects of temperature, space velocity, and molar ratio of sulfur dioxide to methane in the feed on the activity of the cobalt catalyst supported on γ-Al2O3 were investigated. The effect of feed gas containing a hydrogen sulfide contaminant was also studied. A catalyst size-dependence study was performed to determine the influence of the internal diffusion.
National Survey of Radionuclide Gastric Emptying Studies (1997)

A survey was mailed to all institutions in Canada licensed to use radiopharmaceuticals. Questions addressed meal type; mode of preparation; and means, ranges and SD of emptying times. Seventy-eight per cent of 222 facilities responded, including all 55 teaching centres. Eighty-five per cent of teaching and 56% of nonteaching centres perform solid phase gastric emptying studies (GES). The majority use 99mTc sulphur colloid (Tc-SC) added to eggs before cooking as the standard meal. Twenty-five per cent of teaching and 21% of nonteaching centres perform liquid phase GES. Most use a watery solution of 111Indiethylenetriamine pentaacetic acid. Gastric emptying for solid phase GES, expressed as time for 50% emptying (mean t1/2), varied from 42 to 105 mins for centres using the Tc-SC egg meal. Twenty-eight per cent of teaching centres used +/- 2 SD to define their normal range, 26% used +/- 1 SD, 6% used +/- 1.5 SD, and 40% did not know the number of SD used. Twenty per cent of nonteaching centres used +/- 2 SD, 12% used +/- 1 SD and 68% did not know how many SD were used. For liquid phase GES, mean t1/2 varied from 20 to 60 mins. Eighteen per cent of centres used healthy volunteers to establish or validate normal ranges. There is substantial variability among the normal ranges for radionuclide solid and liquid phase GES in both teaching and nonteaching centres across Canada. A minority of facilities have established or validated their own normal ranges in healthy volunteers. There is a need for a more standardized protocol and range of normal, with internal validation by each institution.
Accelerating Fully Homomorphic Encryption over the Integers with Super-size Hardware Multiplier and Modular Reduction. (2013)

Abstract. A fully homomorphic encryption (FHE) scheme is envisioned as being a key cryptographic tool in building a secure and reliable cloud computing environment, as it allows arbitrarily evaluation of a ciphertext without revealing the plaintext. However, existing FHE implementations remain impractical due to their very high time and resource costs. Of the proposed schemes that can perform FHE to date, a scheme known as FHE over the integers has the advantage of comparatively simpler theory, as well as the employment of a much shorter public key making its implementation somewhat more practical than other competing schemes. To the author’s knowledge, this paper presents the first hardware implementations of encryption primitives for FHE over the integers using FPGA technology. First of all, a super-size hardware multiplier architecture utilising the Integer-FFT multiplication algorithm is proposed, and a super-size hardware Barrett modular reduction module is designed incorporating the proposed multiplier. Next, two encryption primitives that are used in two schemes of FHE over the integers are designed employing the proposed super-size multiplier and modular reduction modules. Finally, the proposed designs are implemented and verified on the Xilinx Virtex-7 FPGA platform. Experimental results show that the speed improvement factors of up to 44.72 and 54.42 are available for the two FHE encryption schemes implemented in FPGA when compared to the corresponding software implementations. Meanwhile, the performance analysis shows that further improvement is speed of these FHE encryption primitives may still be possible.
Breakdown Statistics of Gate Dielectric Stacks (2010)

Gate dielectrics of present interest are formed by at least two layers of different materials: an interfacial layer of SiO2-based material and a high dielectric constant (HK) layer. Accurate modeling of the BreakDown (BD) cumulative failure distribution is at the basis of any reliability assessment methodology. In dielectric stacks, this is a non-Weibull distribution which has been recently understood in the framework of the percolation theory. Here, we present a cell-based analytical percolation theory for multiple-layer insulator stacks. The model is validated by comparison with kinetic Monte Carlo simulations of percolation and with large statistical sample size BD experiments on hafnium-based HK/SiO2 stacks. Finally, this analytic model is also applied to single layer dielectrics showing progressive BD.
Asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (2006)

The chiral diphosphinite ligand derived from (R)-1,1′-spirobiindane-7,7′-diol has been found to be highly effective in the Ir-catalyzed asymmetric hydrogenation of quinolines with high substrate/catalyst ratio (up to 5000) and high enantioselectivity (up to 94% ee).
A Surface-Growing Approach to Multi-View Stereo Reconstruction (2007)

We present a new approach to reconstruct the shape of a 3D object or scene from a set of calibrated images. The central idea of our method is to combine the topological flexibility of a point-based geometry representation with the robust reconstruction properties of scene-aligned planar primitives. This can be achieved by approximating the shape with a set of surface elements (surfels) in the form of planar disks which are independently fitted such that their footprint in the input images matches. Instead of using an artificial energy functional to promote the smoothness of the recovered surface during fitting, we use the smoothness assumption only to initialize planar primitives and to check the feasibility of the fitting result. After an initial disk has been found, the recovered region is iteratively expanded by growing further disks in tangent direction. The expansion stops when a disk rotates by more than a given threshold during the fitting step. A global sampling strategy guarantees that eventually the whole surface is covered. Our technique does not depend on a shape prior or silhouette information for the initialization and it can automatically and simultaneously recover the geometry, topology, and visibility information which makes it superior to other state-of-the-art techniques. We demonstrate with several high-quality reconstruction examples that our algorithm performs highly robustly and is tolerant to a wide range of image capture modalities.
Mine Cars of the United States (1956)

Underground transportation of mineral, waste and supplies is a vital function in mine operation. For this reason the selection and design of a mine car is important. Each type of mine car is constructed for a certain type of job. The design of a mine car is the result or product of the many people connected with its construction. It is the purpose of this report to bring forth many of these ideas by way of discussions, statistical classifications and drawings of the mine car.
A Longitudinal Examination of the Neurodevelopmental Impact of Prenatal Immune Activation in Mice Reveals Primary Defects in Dopaminergic Development Relevant to Schizophrenia (2010)

Prenatal exposure to infection is a significant environmental risk factor in the development of schizophrenia and related disorders. Recent evidence indicates that disruption of functional and structural dopaminergic development may be at the core of the developmental neuropathology associated with psychosis-related abnormalities induced by prenatal exposure to infection. Using a mouse model of prenatal immune challenge by the viral mimic polyriboinosinic-polyribocytidilic acid, the present study critically evaluated this hypothesis by longitudinally monitoring the effects of maternal immune challenge during pregnancy on structural and functional dopaminergic development in the offspring from fetal to adult stages of life. Our study shows that prenatal immune challenge leads to dopaminergic maldevelopment starting as early as in the fetal stages of life and produces a set of postnatal dopaminergic abnormalities that is dependent on postnatal maturational processes. Furthermore, our longitudinal investigations reveal a striking developmental correspondence between the ontogeny of specific dopaminergic neuropathology and the postnatal onset of distinct forms of dopamine-dependent functional abnormalities implicated in schizophrenia. Prenatal immune activation thus appears to be a significant environmental risk factor for primary defects in normal dopaminergic development and facilitates the expression of postnatal dopamine dysfunctions involved in the precipitation of psychosis-related behavior. Early interventions targeting the developing dopamine system may open new avenues for a successful attenuation or even prevention of psychotic disorders following neurodevelopmental disruption of dopamine functions.
Dynamic electrode force control of resistance spot welding robot (2009)

Although there has been always existing a strong desire to apply adjustable dynamic electrode force in resistance spot welding (RSW) over decades, technical limitation laid a barrier to its implementation and application. However, with the introduction of servo motor control technology into spot welding gun, this issue will not stay unsolvable any more. After a brief introduction of RSW process and currently adopted electrode force control method, this paper presents two potential solutions, with which using dynamic electrode force to achieve preferable weld quality becomes realizable. Experiment results indicate that, supported by advanced motion control technology of ABB industrial robot, dynamic force profile with fast response and high accuracy is achieved, which will fully meet the critical requirements of spot welding process.
Importin α7 Is Essential for Zygotic Genome Activation and Early Mouse Development (2011)

Importin α is involved in the nuclear import of proteins. It also contributes to spindle assembly and nuclear membrane formation, however, the underlying mechanisms are poorly understood. Here, we studied the function of importin α7 by gene targeting in mice and show that it is essential for early embryonic development. Embryos lacking importin α7 display a reduced ability for the first cleavage and arrest completely at the two-cell stage. We show that the zygotic genome activation is severely disturbed in these embryos. Our findings indicate that importin α7 is a new member of the small group of maternal effect genes.
Oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy following coronary angiography A randomized controlled trial and review of the current literature (2004)

Our findings do not support routine prophylactic administration of oral acetylcysteine as an adjunct to saline hydration for the prevention of contrast-induced nephropathy in chronic renal insufficiency patients undergoing coronary angiography.
Revised structures for cytochalasins E and F (1973)

D. C. Aldridge, D. Greatbanks and W. B. Turner, J. Chem. Soc., Chem. Commun., 1973, 551 DOI: 10.1039/C39730000551
Composable memory transactions (2008)

research-article Share on Composable memory transactions Authors: Tim Harris Microsoft Research Microsoft ResearchView Profile , Simon Marlow Microsoft Research Microsoft ResearchView Profile , Simon Peyton Jones Microsoft Research Microsoft ResearchView Profile , Maurice Herlihy Brown University Brown UniversityView Profile Authors Info & Claims Communications of the ACMVolume 51Issue 8August 2008pp 91–100https://doi.org/10.1145/1378704.1378725Published:01 August 2008Publication History 38citation5,072DownloadsMetricsTotal Citations38Total Downloads5,072Last 12 Months5Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Embedding Heterogeneous Data by Preserving Multiple Kernels (2014)

Heterogeneous data may arise in many real-life applications under different scenarios. In this paper, we formulate a general framework to address the problem of modeling heterogeneous data. Our main contribution is a novel embedding method, called multiple kernel preserving embedding (MKPE), which projects heterogeneous data into a unified embedding space by preserving crossdomain interactions and within-domain similarities simultaneously. These interactions and similarities between data points are approximated with Gaussian kernels to transfer local neighborhood information to the projected subspace. We also extend our method for out-of-sample embedding using a parametric formulation in the projection step. The performance of MKPE is illustrated on two tasks: (i) modeling biological interaction networks and (ii) cross-domain information retrieval. Empirical results of these two tasks validate the predictive performance of our algorithm.
An All‐Solid‐State Flexible Micro‐supercapacitor on a Chip (2011)

A facile strategy is reported for design and preparation of flexible micro-supercapacitors on a chip based on patterned electrodes of conducting polyaniline nanowire arrays. The interdigital microelectrode is produced by combining microfabrication technology and an in-situ chemical polymerization approach. The assembled flexible micro-supercapacitor showed superior volumetric capacitance, fast rate capability and reduced leakage current using H2SO4- polyvinyl alcohol gel electrolytes.
A novel atomic layer oxidation technique for EOT scaling in gate-last high-&#x043A;/metal gate CMOS technology (2011)

We demonstrated sub-1nm equivalent oxide thickness (EOT) for a gate-last high-k/metal scheme. This is enabled by (1) controllable 1000°C high temperature atomic layer oxidation on a chemical oxide (chemox) to form <; 0.5 nm high quality SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> interfacial layer (IL); (2) nitrogen profile optimization on post high- k nitridation and anneal. Competitive gate leakage and mobility are achieved at the scaled EOT compared to a chemox IL control (0.2 nm thinner). The physical properties of the gate stack are studied by XPS and SIMS analysis.
Plant Antimutagenic Agents, 4. Isolation and Structure Elucidation of Maesol, an Inactive Constituent of Maesa spp. (1988)

Maesol, a novel dimeric phenol, was isolated from seeds of Maesa montana and Maesa indica. Maesol was shown to have the formula C28H42O4 with structure 1, a dimeric, symmetrical 1,12-bis(3,3'-dihydroxy-4,4'-dimethyl-5,5'-dimethoxyphenyl)dodecane. It is the first compound with such structure to be isolated from plant material. Structure elucidation was based largely on 1H- and 13C-nmr techniques and comparison with a known synthetic isomeric dimer 3. Although crude extracts showed strong inhibition of 2-aminoanthracene activity against Salmonella typhimurium (T-98), the pure compound was inactive when tested for inhibition of the mutagenic activity of several mutagens.
Eliminating the address translation bottleneck for physical address cache (1992)

article Free Access Share on Eliminating the address translation bottleneck for physical address cache Authors: Tzi-cker Chiueh View Profile , Randy H. Katz View Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 27Issue 9Sept. 1992 pp 137–148https://doi.org/10.1145/143371.143501Online:01 September 1992Publication History 28citation522DownloadsMetricsTotal Citations28Total Downloads522Last 12 Months19Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Cement chemistry (1997)

H F W Taylor was for many years Professor of Inorganic Chemistry at he University of Aberdeen, Scotland. Since 1948, his main research interest has been the chemistry of cement. His early work laid the foundations of our understanding of the structure at the nanometre level of C-S-H, the principal product formed when cement is mixed with water, and the one mainly reponsible for its hardening. Subsequent studies took him into many additional aspects of the chemistry and materials science of cement and concrete. His work has been recognized by Fellowships and by other honours and awards.
Degradation in Peritoneal Dialysis Fluids May be Avoided by Using Low pH and High Glucose Concentration (2001)

In order to minimize the development of bioincompatible GDPs in peritoneal dialysis fluids during heat sterilization, pH should be kept around 3.2 and the concentration of glucose should be high. 5-HMF and 284 nm UV absorbance are not reliable as quality measures. 3-DG and the portion of UV absorbance at 228 nm caused by degradation products other than 5-HMF seem to be reliable indicators of bioincompatibility.
Pharmacological Inhibition of Microsomal Prostaglandin E Synthase-1 Suppresses Epidermal Growth Factor Receptor-Mediated Tumor Growth and Angiogenesis (2012)

Our work demonstrates that the pharmacological inhibition of mPGES-1 reduces squamous carcinoma growth by suppressing PGE(2) mediated-EGFR signalling and by impairing tumor associated angiogenesis. These results underscore the potential of mPGES-1 inhibitors as agents capable of controlling tumor growth.
Automatic image event segmentation and quality screening for albuming applications (2000)

In this paper, a system for automatic albuming of consumer photographs is described, and its specific core components of event segmentation and screening of low quality images are discussed. A novel event segmentation algorithm was created to automatically cluster pictures into events and sub-events for albuming, based on date/time metadata information as well as color content of the pictures. A new quality-screening algorithm is developed based on object quality measures, to detect problematic images due to underexposure, low contrast, and camera defocus or movement. Performance testing of these algorithms was conducted using a database of real consumer photos and showed that these functions provide a useful firstcut album layout for typical rolls of consumer pictures. A first version of the automatic albuming application software was tested through a consumer trial in the United States from August to December 1999. I.
Negative ion mass spectra and particulate formation in radio frequency silane plasma deposition experiments (1993)

Negative ions have been clearly identified in silane rf plasmas used for the deposition of amorphous silicon. Mass spectra were measured for monosilicon up to pentasilicon negative ion radical groups in power-modulated plasmas by means of a mass spectrometer mounted just outside the glow region. Negative ions were only observed over a limited range of power modulation frequency which corresponds to particle-free plasma conditions. The importance of negative ions regarding particulate formation is demonstrated and commented upon.