gebhart/patrepeval huggingface dataset:
A distributed BIST control scheme for complex VLSI devices (2002)

BIST is a viable approach to test today's digital systems. Constraints, such as power, noise, area overhead, and others, limit the possibilities of parallel BIST execution in complex VLSI devices. This paper presents a BIST scheduling process that takes into consideration such constraints, and introduces a new BIST control methodology, that implements the BIST schedule with a highly modular architecture. In fact, due to the uniformity of interface, the BIST control elements are independent of the BIST scheme used in the embedded blocks of a device. This BIST control architecture can provide block level diagnostic information.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Diffused ferroelectrics of Ba6Ti2Nb8O30 and Sr6Ti2Nb8O30 with filled tungsten-bronze structure (2005)

We have synthesized ferroelectrics of M6Ti2Nb8O30 (M=Ba, Sr) with filled tungsten-bronze structure. The microstructures and dielectric properties of the present materials have been investigated as well as the behavior and features of the ferroelectric phase transition. Similar to perovskite ABO3, tungsten-bronze structure consists of several BO6 octahedra. The close distortion of BO6 octahedra concluded from the 10c∕a ratios is observed in Ba6Ti2Nb8O30 and Sr6Ti2Nb8O30, and two ferroelectrics have the close Curie temperature (155°C for the former and 160°C for the latter at 1MHz). Deducing from Raman spectra at different temperatures around phase transition and the modified Curie-Weiss law, the ferroelectric phase transition of Ba6Ti2Nb8O30 and Sr6Ti2Nb8O30 may belong to the displacive transition. The obvious diffuse characteristics of the ferroelectric transition may be attributed to the disordered distributions of octahedra, as two kinds of BO6, i.e., TiO6 and NbO6, exist in one cell. The weak ferroelectric of the present materials are indicated from the P-E hysteresis loops, both with 2Pr of 4μC∕cm2.
Synthesis and Biological Activity of 2-Aminothiazolines and 2-Mercaptothiazolines as Octopaminergic Agonists (1991)

Journal Article Synthesis and Biological Activity of 2-Aminothiazolines and 2-Mercaptothiazolines as Octopaminergic Agonists Get access Akinori Hirashima, Akinori Hirashima Department of Agricultural Chemistry, Kyushu University, 46–02, Fukuoka 812, Japan Search for other works by this author on: Oxford Academic Google Scholar Yutaka Yoshii, Yutaka Yoshii Department of Agricultural Chemistry, Kyushu University, 46–02, Fukuoka 812, Japan Search for other works by this author on: Oxford Academic Google Scholar Morifusa Eto Morifusa Eto Department of Agricultural Chemistry, Kyushu University, 46–02, Fukuoka 812, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 55, Issue 10, 1 October 1991, Pages 2537–2545, https://doi.org/10.1080/00021369.1991.10871030 Published: 01 October 1991 Article history Received: 09 April 1991 Published: 01 October 1991
Elevated cholecystokininergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse (2006)

Cholecystokinin (CCK), one of the most abundant neuropeptides in the brain, plays an important role in anxiogenesis through the activation of CCK receptor-2 (CCKR-2). Accumulating evidence, however, has suggested this role depends on endogenous CCKergic "tone," which is largely determined by the expression level of the CCKR-2. Using the tTA/tetO-inducible transgenic (tg) approach, we show here that overexpression of the CCKR-2 in neurons of the forebrain significantly increases CCKR-2 binding capacity in tg mice compared with their littermate controls. Interestingly, these tg mice consistently exhibit increased fear responses, which are generally interpreted as anxiety-like behaviors in the rodent, in a battery of behavioral tests, which represented conflict situations or delivered stress to the subjects. The inhibition of transgene expression with doxycycline treatment completely diminished both increased receptor-binding activity and all behavioral phenotypes. Furthermore, treatment of tg mice with diazepam significantly attenuated these anxiety-like behaviors. Our results directly demonstrate that the elevated CCKergic tone via overexpression of the CCKR-2 in the brain may constitute an underlying molecular/neuronal mechanism for the expression of anxiety. In addition, our study has validated a robust genetic anxiety model in the mouse in terms of their face, constructive, and predictive validity.
Fabrication and <i>In Vivo</i> Microanastomosis of Vascularized Tissue-Engineered Constructs (2014)

Tissue engineering endeavors to create replacement tissues and restore function that may be lost through infection, trauma, and cancer. However, wide clinical application of engineered scaffolds has yet to come to fruition due to inadequate vascularization. Here, we fabricate hydrogel constructs using Pluronic(®) F127 as a sacrificial microfiber, creating microchannels within biocompatible, biodegradable type I collagen matrices. Microchannels were seeded with human umbilical vein endothelial cells (HUVEC) or HUVEC and human aortic smooth muscle cells (HASMC) in co-culture, generating constructs with an internal endothelialized microchannel. Histological analysis demonstrated HASMC/HUVEC-seeded constructs with a confluent lining after 7 days with preservation and further maturation of the lining after 14 days. Immunohistochemical staining demonstrated von Willebrand factor and CD31(+) endothelial cells along the luminal surface (neointima) and alpha-smooth muscle actin expressing smooth muscle cells in the subendothelial plane (neomedia). Additionally, the deposition of extracellular matrix (ECM) components, heparan sulfate and basal lamina collagen IV were detected after 14 days of culture. HUVEC-only- and HASMC/HUVEC-seeded microchannel-containing constructs were microsurgically anastomosed to rat femoral artery and vein and perfused, in vivo. Both HUVEC only and HUVEC/HAMSC-seeded constructs withstood physiologic perfusion pressures while their channels maintained their internal infrastructure. In conclusion, we have synthesized and performed microvascular anastomosis of tissue-engineered hydrogel constructs. This represents a significant advancement toward the generation of vascularized tissues and brings us closer to the fabrication of more complex tissues and solid organs for clinical application.
Revalidation of the Rayleigh resolution and DOF limits (1998)

Currently, the fundamental relationships which establish the limits to optical imaging appear useful only as comparative metrics for microlithographic applications. Furthermore, with the continual advances in optical lithography, the validity of such 'rules-of-thumb' become suspect. A set of universal equations would be useful but additional description and expansion beyond the Rayleigh definitions is needed for application to current technologies. Relationships which govern the limits of resolution and focal depth are presented here in order to develop a more complete description for various lithographic imaging situations. Expanded Rayleigh definitions can then allow for insight into fundamental limitations and scaling for conventional partially coherent imaging, imaging with off-axis illumination, and phase-shift masking. Depth of focus relationships are also expanded to describe the distribution of diffraction orders over the lens pupil and are modified to accommodate feature pitch and partial coherence. Such analysis can allow for a more thorough understanding and prediction of performance for a given lithographic technology.
Design of a Microstrip Diplexer and Triplexer Using Open Loop Resonators (2016)

In this paper a novel design of microstrip diplexer and triplexer using open loop resonators is presented. The proposed diplexer if formed by two band-pass filters for the Industrial Scientific Medical (ISM) applications at 5.8 GHz and the WIMAX applications (IEEE 802.16 WiMAX at 3.17 GHz to 4.2 GHz bands). The microstrip triplexer is designed for the Digital Communication System (DCS) at 1.8 GHz, WIMAX at 3.2 GHz and for the C-band at 4.4 GHz. Each device is formed by a set of filters with a matching network by using open loop resonators and a good arrangement of the transmission feed lines. Several parametric studies were achieved to study the influence of some critical parameters on the performances of the proposed circuits. The LC equivalent circuit of the band pass filter is examined and the values of its components are calculated. ADS Agilent and CST-MWS solvers are used to predict the electrical performances of the proposed circuits. The simulated frequency responses of these structures show good results with insertion losses around 2 dB, return losses better than 20 dB for all channels, and an isolation between all bands better than 20 dB. Besides, several transmission zeros are observed near the pass bands which enhance the selectivity and the isolation of the proposed devices.
Cyclopentadienyl compounds of metals and metalloids (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyclopentadienyl compounds of metals and metalloidsMarvin D. Rausch Cite this: J. Chem. Educ. 1960, 37, 11, 568Publication Date (Print):November 1, 1960Publication History Received3 August 2009Published online1 November 1960Published inissue 1 November 1960https://doi.org/10.1021/ed037p568RIGHTS & PERMISSIONSArticle Views765Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (9 MB) Get e-Alerts Get e-Alerts
Distribution and Transport of Cholesterol-rich Membrane Domains Monitored by a Membrane-impermeant Fluorescent Polyethylene Glycol-derivatized Cholesterol (2004)

Cholesterol-rich membrane domains function in various membrane events as diverse as signal transduction and membrane traffic. We studied the interaction of a fluorescein ester of polyethylene glycol-derivatized cholesterol (fPEG-Chol) with cholesterol-rich membranes both in cells and in model membranes. Unlike filipin and other cholesterol probes, this molecule could be applied as an aqueous dispersion to various samples. When added to live cells, fPEG-Chol distributed exclusively in the outer plasma membrane leaflet and was enriched in microdomains that dynamically clustered by the activation of receptor signaling. The surface-bound fPEG-Chol was slowly internalized via clathrin-independent pathway into endosomes together with lipid raft markers. Noteworthy, fPEG-Chol could be microinjected in the living cells in which we found Golgi apparatus as the sole major organelle to be labeled. PEG-Chol, thus, provides a novel, sensitive probe for unraveling the dynamics of cholesterol-rich microdomains in living cells.
Quantum Random Number Generator using Photon-Number Path Entanglement (2009)

We report a novel quantum random number generator based on the photon-number—path entangled state which is prepared via two-photon quantum interference at a beam splitter. The randomness in our scheme is of truly quantum mechanical origin as it comes from the projection measurement of the entangled two-photon state. The generated bit sequences satisfy the standard randomness test.
Prevalence of the <i>NKG2D</i> Thr72Ala Polymorphism in Patients with Cervical Carcinoma (2012)

Our studies may suggest that the women with cervical cancer bearing the NKG2D 72Thr gene variant might be protected against progression to advanced stages of this cancer.
KNOWME: a case study in wireless body area sensor network design (2012)

Wireless body area sensing networks have the potential to revolutionize health care in the near term. The coupling of biosensors with a wireless infrastructure enables the real-time monitoring of an individual's health and related behaviors continuously, as well as the provision of realtime feedback with nimble, adaptive, and personalized interventions. The KNOWME platform is reviewed, and lessons learned from system integration, optimization, and in-field deployment are provided. KNOWME is an endto- end body area sensing system that integrates off-the-shelf sensors with a Nokia N95 mobile phone to continuously monitor and analyze the biometric signals of a subject. KNOWME development by an interdisciplinary team and in-laboratory, as well as in-field deployment studies, employing pediatric obesity as a case study condition to monitor and evaluate physical activity, have revealed four major challenges: (1) achieving robustness to highly varying operating environments due to subject-induced variability such as mobility or sensor placement, (2) balancing the tension between acquiring high fidelity data and minimizing network energy consumption, (3) enabling accurate physical activity detection using a modest number of sensors, and (4) designing WBANs to determine physiological quantities of interest such as energy expenditure. The KNOWME platform described in this article directly addresses these challenges.
Development of an electrochemical micromachining (μECM) machine (2015)

This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University London.
Synthesis, characterization, and properties of new thermally curable polyetheresters containing benzoxazine moieties in the main chain (2007)

Abstract High molecular weight polyetheresters (PEE) containing thermally curable benzoxazine units in the main chain have been synthesized. For this purpose, first the diol functional monomer is synthesized through the Mannich reaction of 4,4′‐isopropylidenediphenol (bisphenol A), formaldehyde, and 2‐(2‐aminoethoxy)ethanol. Polycondensation of the resulting benzoxazine dietherdiol with adipoyl chloride and terephthaloyl dichloride in the presence of triethyl amine yields the corresponding PEE with the molecular weights of 34.000 Da. The structures of the precursor diol monomer and the resulting PEEs are confirmed by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance spectroscopy ( 1 H‐NMR) analysis. Curing behavior of both the monomer and polymers has also been studied by differential scanning calorimetry (DSC). Flexible free standing transparent films of the PEEs are obtained by solvent casting from dichloromethane solution on Teflon plates. The films preserve shape and, to some extent, toughness after thermal curing between 140 and 220 °C. Thermal properties of the cured polymers are also investigated by thermogravimetric analysis (TGA). © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 414–420, 2008
Genetic Variations in the Sodium Balance-Regulating Genes <i>ENaC</i>, <i>NEDD4L</i>, <i>NDFIP2</i> and <i>USP2</i> Influence Blood Pressure and Hypertension (2010)

These results support our hypothesis that individual variations in blood pressure are attributed to variants of the genes that regulate renal sodium reabsorption and excretion. Our data also suggest that it would be meaningful to investigate the role of NEDD4L-mediated ubiquitination in the pathogenesis of hypertension.
Anthraquinonedisulfonate adsorption, electron-transfer kinetics, and capacitance on ordered graphite electrodes: the important role of surface defects (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnthraquinonedisulfonate adsorption, electron-transfer kinetics, and capacitance on ordered graphite electrodes: the important role of surface defectsMark T. McDermott, Kristin Kneten, and Richard L. McCreeryCite this: J. Phys. Chem. 1992, 96, 7, 3124–3130Publication Date (Print):April 1, 1992Publication History Published online1 May 2002Published inissue 1 April 1992https://pubs.acs.org/doi/10.1021/j100186a063https://doi.org/10.1021/j100186a063research-articleACS PublicationsRequest reuse permissionsArticle Views1051Altmetric-Citations157LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Chemical synthesis and physiological activity of sulfonium analogues of platelet activating factor (1991)

Phosphatidylsulfocholine (PSC), the sulfonium analogue of phosphatidylcholine (PC), occurs naturally in some diatoms. The replacement of the [formula; see text] group by a [formula; see text] results in an increase in the polar head group size in PSC relative to that of PC, consistent with the observed increase in permeability of PSC bilayers towards urea. It was of interest to see whether replacement of the [formula; see text] group in platelet activating factor (PAF) by an [formula; see text] group leads to any change in platelet aggregation or other physiological activity. Synthesis of the sulfonium analogue of PAF was carried out by suitable modifications of known procedures. The PAF-sulfonium analogue was found to have almost the same platelet aggregating activity as PAF itself, in the concentration range 1-20 microM, but a much lower activity in the range 0.01-1 microM. The analogue had little or no effect on the platelet aggregation activity of PAF when added in the concentration range 0.01-1 microM and had about half the hypotensive activity of PAF towards hypertensive CDF male rats. The sulfonium analogue, however, was much more cytotoxic to HL-60 cells than PAF itself, in the concentration range 0-15 microM; replacement of the acetate group by a benzyl group increased the cytotoxicity to the level of that of the methoxy analogue of PAF. Thus, replacement of the [formula; see text] group by a [formula; see text] group in the polar head group region of PAF results in a relatively small change in its platelet aggregation activity and a decrease in its hypotensive activity, but greatly increases its antitumor activity.
Face recognition based on collaborative image similarity assessment (2012)

In this paper, we propose an innovative approach for face recognition based on collaborative image similarity assessment (CISA). In the proposed method, the test sample is first represented by a linear combination of all the training samples for each face class. The classification task is then conducted using the similarity measures including structure similarity index measure (SSIM), root mean square (RMS), and similarity assessment value (SAV). Since CISA is only one phase, it is computationally efficient when comparing with the method of two-phase test sample sparse representation (TPTSR). To verify the performance of face classification, two popular face databases of the ORL and FERET are used. Results show that CISA is comparable with TPTSR on the classification rates for ORL database. However, CISA greatly outperforms TPTSR on the evaluation of the FERET database. Moreover, only 276.4ms on an average is required for CISA in the classification of each test sample but it needs 800.8ms for TPTSR.
Is urbanization contributing to higher food prices? (2010)

Urbanization has been mentioned as one possible cause of higher food prices, and in this paper we examine some of the suggested links between urbanization and food prices. We conclude that urbanization, conventionally defined as the increasing share of the population living in urban settlements, is being conflated with related but separate processes, such as economic growth, population growth and environmental degradation. We discuss factors that affect food prices and conclude that the one important way in which urbanization in poor countries may affect food prices is that it increases the number of households that depend on commercial food supplies, rather than on own production, as their main source, and hence are likely to hoard food if they fear future price increases. One policy option for managing this is larger food reserves. Attempts to curb urbanization, on the other hand, would be ill-advised.
An unusual manifestation of bleeding diathesis in a patient with osteogenesis imperfecta (1997)

We present the anaesthetic and surgical management, and post-operative course of a patient with osteogenesis imperfecta which exemplifies the problems associated with this condition. The observed petechial haemorrhagic rash is not characteristic of the bleeding tendency in osteogenesis imperfecta nor characteristic of acute disseminated intravascular coagulation. Despite potential life-threatening complications the patient made a good recovery and was discharged 3 weeks after surgery.
Sc(III)-Catalyzed Enantioselective Addition of Thiols to α,β-Unsaturated Ketones in Neutral Water (2011)

This report concerns Lewis acid catalyzed enantioselective sulfa-Michael addition in neutral water by using a very efficient Sc(OTf)(3)/bipyridine 1 catalytic system. It is noteworthy that the protocol presented employs water as a reaction medium and allows us to obtain very high stereoselectivity and satisfactory yields for β-keto sulphides deriving from aliphatic thiols. The recovery and reuse of both the aqueous medium and the catalytic system is also reported.
Crystal Structure of 6α-(Hydroxymethyl)penicillanate Complexed to the TEM-1 β-Lactamase from <i>Escherichia coli</i>:  Evidence on the Mechanism of Action of a Novel Inhibitor Designed by a Computer-Aided Process (1996)

The crystal structure of the complex of the TEM-1 β-lactamase from Escherichia coli inhibited by 6α-(hydroxymethyl)penicillanic acid (1) is reported herein. This is the first structure for an acyl-enzyme intermediate with a substrate reported for a native class A β-lactamase. This compound was designed and synthesized as a molecule that would acylate the active site of the enzyme, but would resist deacylation by virtue of the fact that its C6α hydroxymethyl moiety was expected to occupy the space near the hydrolytic water molecule (J. Am. Chem. Soc. 1995, 117, 11055). The crystal structure of the acyl-enzyme species is closely similar to one of the two energy-minimized acyl-enzyme models generated in the course of the design aspect of the work. The crystal structure provides evidence for a number of mechanistic features for the inhibition process and the ultimate recovery of the activity. Our results reported herein are consistent with the side-chain carboxylate of Glu-166 being the active-site basic function that activates the hydrolytic water for the deacylation step in the course of catalysis by class A β-lactamases. The design principles applied for compound 1 hold the promise of general utility for development of novel inhibitors for other hydrolytic enzymes.