gebhart/patrepeval huggingface dataset:
<i>GmCOI1</i>, a Soybean F-Box Protein Gene, Shows Ability to Mediate Jasmonate-Regulated Plant Defense and Fertility in <i>Arabidopsis</i> (2005)

The F-box protein gene COI1 from Arabidopsis plays a fundamental role in response to jasmonates, which regulate plant root growth, pollen fertility, wounding and healing, and defense against pathogens and insects. Null mutations in COI1 were previously found to abolish all the jasmonate responses, and the Arabidopsis coil-1 mutant is male sterile and susceptible to pathogen infection. In this study, we isolated an F-box protein gene from soybean, which shares significant homology with the Arabidopsis COI1 and similarly contains an F-box motif and leucine rich repeats (LRR), here designated GmCOI1 (Glycine max L. (Merr.) COI1). To test whether the sequence homology and structural similarity are indicative of functional conservation, we expressed GmCOI1 in the Arabidopsis coil-1 mutant. The transgenic coil-1 plants with expression of the GmCOI1 gene were found to exhibit normal jasmonate responses, including jasmonate-regulated plant defense and fertility. In addition, the chimerical proteins with swapped domain of the F-box motif or LRR between GmCOI1 and COI1 were shown to functionally complement the coil-1 mutation. Furthermore, GmCOI1 was found to assemble into the Skpl-Cullin-F-box (SCF) complexes, similar to the formation of the Arabidopsis SCF(COO1). These data demonstrate the soybean F-box protein gene GmCOI1 is able to mediate jasmonate-regulated plant defense and fertility in Arabidopsis, which implies a generic jasmonate pathway with conserved signal components in different plant species.
Phase sensitive investigations of 3×3 singlemode fibre directional couplers (1993)

The recently published method for evaluating the phase difference between the output signals of singlemode fibre 2×2 directional couplers by means of pure amplitude measurements has been extended to 3×3 couplers.
INSTITUTOS DE SALUD DE EU FINANCIAN ESTUDIOS EN BIOMÉDICAS (2000)

EL INVESTIGADOR GERARDO GAMBA AYALA, DE LA UNIDAD PERIFERICA DEL INSTITUTO DE INVESTIGACIONES BIOMEDICAS, RECIBIR  FINANCIAMIENTO DE INSTITUTOS NACIONALES DE SALUD DE ESTADOS UNIDOS PARA PROFUNDIZAR EN LOS ESTUDIOS QUE REALIZA ACERCA DE LA PROTEINA COTRANSPORTADOR DE SODIO, POTASIO Y CLORO. DICHA PROTEINA INTERVIENE EN LA CAPACIDAD DE CONCENTRACION DE LA ORINA DE LOS SERES HUMANOS Y PERMITE RECUPERAR LAS GRANDES CANTIDADES DE ESTE LIQUIDO QUE SE REQUIEREN PARA ELIMINAR SOLUTOS. LA IMPORTANCIA DE LA INVESTIGACION RADICA EN QUE AL ENTENDER LAS FUNCIONES DE ESA PROTEINA PODR N DISENARSE MEDICAMENTOS M S EFICACES PARA CONOCER ADECUADAMENTE SUS MECANISMOS DE REGULACION, LO QUE FACILITAR  EL MANEJO DE LAS ENFERMEDADES QUE INVOLUCRAN SU FUNCIONAMIENTO. EL DOCTOR GAMBA RECIBIR  70 MIL DOLARES ANUALES DURANTE CINCO ANOS.
MIF-like activity of natural and recombinant human interferon-<i>gamma</i> and their neutralization by monoclonal antibody. (1985)

By utilizing elutriation-purified human monocytes, we found that human interferon (IFN) inhibits monocyte migration in a manner similar to migration inhibitory factor (MIF) and does it without demonstrable cytotoxicity. We observed that human IFN-gamma is 10 to 300 times more potent in its MIF activity than is IFN-alpha and that monoclonal antibodies (MoAb) can be used to distinguish between them. Studies with recombinant IFN-gamma indicate that the migration inhibition seen with natural IFN-gamma is due to IFN-gamma itself and is not due to co-purification of another lymphokine with the natural IFN-gamma. Although interferons exhibit MIF activities, there are apparently other cytokines, without antiviral activity, that also have MIF activities. MIF from the lymphoblastoid cell line RPMI 1788 was not neutralized by MoAb to IFN. However, MIF activity in supernatant fluid from human peripheral blood lymphocyte cultures stimulated with Con A-Sepharose was completely neutralized with MoAb anti-IFN-gamma. These data indicate that MIF is really a family of cytokines that inhibit macrophage/monocyte migration and that the major portion of MIF activity associated with crude supernatant of mitogen-stimulated lymphocytes is due to IFN-gamma.
Speech recognition for multiple non-native accent groups with speaker-group-dependent acoustic models (2004)

In this paper, the recognition performance for non-native English speech with two different kinds of speaker-groupdependent acoustic models is investigated. The approaches for creating speaker groups include knowledge-based grouping of non-native speakers by their first language, and the automatic clustering of speakers. Clustering is based on speakerdependent acoustic models in speaker Eigenspace. The acoustic model for each speaker group is obtained by bootstrapping with pre-segmented speech data or adaptation of a speakerindependent native baseline model. For the decoding of a nonnative speaker’s utterance not seen during the training or adaptation phase, the selection of a model suitable to cope with the accent characteristics of that speaker is necessary. Here, ideal selection via an oracle and parallel decoding are examined. Evaluation is conducted in a hotel reservation task for five major accent groups, including German, French, Indonesian, Chinese and Japanese speakers. Recognition results with speakerdependent and an accent-independent non-native model will also be reported.
Diagnosis and Treatment of Status Epilepticus (2020)

The definition of status epilepticus (SE) was revised recently in accordance with the various evidences of neuronal injury and changes in clinical settings. Currently, the most acceptable duration of continuous seizure activity is 5 minutes. In 2015, the International League Against Epilepsy Task Force, which was convened to develop a definition and classification of SE, presented a new classification based on four axes: 1) semiology, 2) etiology, 3) electroencephalogram (EEG) correlates, and 4) age. The essential element of nonconvulsive SE (NCSE) is the presence of neurological abnormalities induced by a prolonged epileptic process. The definition of refractory SE involves either clinical or electrographic seizures that persist after adequate doses of an initial benzodiazepine and acceptable second-line antiseizure drugs. The use of EEG is critical in the diagnosis and treatment of NCSE. However, there are a wide range of EEG abnormalities in NCSE. Both the Neurocritical Care Society and the American Epilepsy Society have suggested a paradigm for treating convulsive SE (CSE). The first-line treatment of CSE with benzodiazepine is well-established. The second-line treatment comprises intravenous (IV) doses of fosphenytoin (phenytoin), valproate, phenobarbital, levetiracetam, or midazolam. Although fosphenytoin (phenytoin) and valproate are commonly used in NCSE, the effectiveness of antiepileptic drugs (AEDs) on NCSE has not been well studied. New AEDs such as IV levetiracetam and lacosamide can also be used to treat NCSE with fewer side effects and drug-drug interactions. For refractory SE, general anesthesia with IV midazolam, propofol, pentobarbital, or thiopental could be applied. Use of ketamine, megadose phenobarbital therapy, and multiple combinations of various AEDs including high doses of oral AEDs can also be considered. New-onset refractory status epilepticus (NORSE) and its subcategory, febrile infection-related epilepsy syndrome, involve autoimmune processes. AEDs alone are poorly effective in the treatment of SE in autoimmune encephalitis. Immunotherapy such as steroids, immunoglobulin, rituximab, or tocilizumab can be effective.
Combined noninvasive metabolic and spindle imaging as potential tools for embryo and oocyte assessment (2019)

Supported by the Blavatnik Biomedical Accelerator Grant at Harvard University and by the Harvard Catalyst/The Harvard Clinical and Translational Science Center (National Institutes of Health Award UL1 TR001102), by NSF grants DMR-0820484 and PFI-TT-1827309 and by NIH grant R01HD092550-01. T.S. was supported by a National Science Foundation Postdoctoral Research Fellowship in Biology grant (1308878). S.F. and S.A. were supported by NSF MRSEC DMR-1420382. Becker and Hickl GmbH sponsored the research with the loaning of equipment for FLIM. T.S. and D.N. are cofounders and shareholders of LuminOva, Inc., and co-hold patents (US20150346100A1 and US20170039415A1) for metabolic imaging methods. D.S. is on the scientific advisory board for Cooper Surgical and has stock options with LuminOva, Inc.
Fehlerbetrachtung (1964)

Im folgenden Kapitel werden die Fehlergrößen diskutiert, die das Meßergebnis beeinflussen können. Sie lassen sich einteilen in Fehler, die abhängig sind
Immune Escape of Relapsed AML Cells after Allogeneic Transplantation (2018)

AML relapse after transplantation was not associated with the acquisition of relapse-specific mutations in immune-related genes. However, it was associated with dysregulation of pathways that may influence immune function, including down-regulation of MHC class II genes, which are involved in antigen presentation. These epigenetic changes may be reversible with appropriate therapy. (Funded by the National Cancer Institute and others.).
PENTUAN LOKASI MOORING BUOY DENGAN METODE CENTER OF GRAFITY UNTUK OPTIMALISASI BAHAN BAKAR KAPAL (STUDI KASUS: PT. PERTAMINA HULU ENERGI WEST MADURA OFFSHORE) (2016)

Jika membutuhkan abstrak atau isi jurnal silahkan menghubungi author melalui email nurudini_diar@gmail.com, novareza15@ub.ac.id, ceria_fmt@ub.ac.id
Impact of virtual execution environments on processor energy consumption and hardware adaptation (2006)

During recent years, microprocessor energy consumption has been surging and efforts to reduce power and energy have received a lot of attention. At the same time, virtual execution environments (VEEs), such as Java virtual machines, have grown in popularity. Hence, it is important to evaluate the impact of virtual execution environments on microprocessor energy consumption. This paper characterizes the energy and power impact of two important components of VEEs, Just-in-time(JIT) optimization and garbage collection. We find that by reducing instruction counts, JIT optimization significantly reduces energy consumption, while garbage collection incurs runtime overhead that consumes more energy. Importantly, both JIT optimization and garbage collection decrease the average power dissipated by a program. Detailed analysis reveals that both JIT optimizer and JIT optimized code dissipate less power than un-optimized code. On the other hand, being memory bound and with low ILP, the garbage collector dissipates less power than the application code, but rarely affects the average power of the latter.Adaptive microarchitectures are another recent trend for energy reduction where microarchitectural resources can be dynamically tuned to match program runtime requirements. This research reveals that both JIT optimization and garbage collection alter a program's behavior and runtime requirements, which considerably affects the adaptation of configurable hardware units, and influences the overall energy consumption. This work also demonstrates that the adaptation preferences of the two VEE services differ substantially from those of the application code. Both VEE services prefer a simple core for high energy reduction. On the other hand, the JIT optimizer usually requires larger data caches, while the garbage collector rarely benefits from large data caches. The insights gained in this paper point to novel techniques that can further reduce microprocessor energy consumption.
Respiratory-gated CT as a tool for the simulation of breathing artifacts in PET and PET/CT (2008)

Respiratory motion in PET and PET/CT blurs the images and can cause attenuation-related errors in quantitative parameters such as standard uptake values. In rare instances, this problem even causes localization errors and the disappearance of tumors that should be detectable. Attenuation errors are severe near the diaphragm and can be enhanced when the attenuation correction is based on a CT series acquired during a breath-hold. To quantify the errors and identify the parameters associated with them, the authors performed a simulated PET scan based on respiratory-gated CT studies of five lung cancer patients. Diaphragmatic motion ranged from 8 to 25 mm in the five patients. The CT series were converted to 511-keV attenuation maps which were forward-projected and exponentiated to form sinograms of PET attenuation factors at each phase of respiration. The CT images were also segmented to form a PET object, moving with the same motion as the CT series. In the moving PET object, spherical 20 mm mobile tumors were created in the vicinity of the dome of the liver and immobile 20 mm tumors in the midchest region. The moving PET objects were forward-projected and attenuated, then reconstructed in several ways: phase-matched PET and CT, gated PET with ungated CT, ungated PET with gated CT, and conventional PET. Spatial resolution and statistical noise were not modeled. In each case, tumor uptake recovery factor was defined by comparing the maximum reconstructed pixel value with the known correct value. Mobile 10 and 30 mm tumors were also simulated in the case of a patient with 11 mm of breathing motion. Phase-matched gated PET and CT gave essentially perfect PET reconstructions in the simulation. Gated PET with ungated CT gave tumors of the correct shape, but recovery was too large by an amount that depended on the extent of the motion, as much as 90% for mobile tumors and 60% for immobile tumors. Gated CT with ungated PET resulted in blurred tumors and caused recovery errors between -50% and +75%. Recovery in clinical scans would be 0%-20% lower than stated because spatial resolution was not included in the simulation. Mobile tumors near the dome of the liver were subject to the largest errors in either case. Conventional PET for 20 mm tumors was quantitative in cases of motion less than 15 mm because of canceling errors in blurring and attenuation, but the recovery factors were too low by as much as 30% in cases of motion greater than 15 mm. The 10 mm tumors were blurred by motion to a greater extent, causing a greater SUV underestimation than in the case of 20 mm tumors, and the 30 mm tumors were blurred less. Quantitative PET imaging near the diaphragm requires proper matching of attenuation information to the emission information. The problem of missed tumors near the diaphragm can be reduced by acquiring attenuation-correction information near end expiration. A simple PET/CT protocol requiring no gating equipment also addresses this problem.
Suggested health services research action to achieve reduction of neonatal mortality in India (2011)

Despite several national programs to reduce infant mortality, India had repeatedly failed to achieve its set targets for infant mortality. There are approximately one million neonatal deaths in India each year which accounts for nearly two-thirds of the infant deaths in India. India’s current trajectories of neonatal and infant mortality rates make it unlikely that it will achieve its targets for infant mortality rate for 2015 set under the Millennium Development Goals. Since two-thirds of infant deaths in India are neonatal deaths, implementation of effective neonatal care strategies would be essential to reduce infant mortality considerably. The history of child health services in India suggests an inattention to qualitative parameters, hindering a reversal of its failures. We discuss a format of mixed-methods participatory research, integrated with routine district level household surveys (DLHS), as a model of health services research which would better delineate the problems encountered in delivering effective newborn care at the primary care level.
ChemInform Abstract: APPLICATIONS OF (119)SN CHEMICAL SHIFTS TO STRUCTURAL TIN CHEMISTRY (1974)

Abstract Übersicht ‐ Klassifikation der Zinnverbindungen in 30 Einheiten und Tabellarisierung ihrer chemischen Verschiebungen, wobei diese durch direkte Messungen und Doppel‐Resonanz‐Methode erfolgt.
Big Data: New Tricks for Econometrics (2014)

Computers are now involved in many economic transactions and can capture data associated with these transactions, which can then be manipulated and analyzed. Conventional statistical and econometric techniques such as regression often work well, but there are issues unique to big datasets that may require different tools. First, the sheer size of the data involved may require more powerful data manipulation tools. Second, we may have more potential predictors than appropriate for estimation, so we need to do some kind of variable selection. Third, large datasets may allow for more flexible relationships than simple linear models. Machine learning techniques such as decision trees, support vector machines, neural nets, deep learning, and so on may allow for more effective ways to model complex relationships. In this essay, I will describe a few of these tools for manipulating and analyzing big data. I believe that these methods have a lot to offer and should be more widely known and used by economists.
Host Specificity of Ovine Bordetella parapertussis and the Role of Complement (2015)

The classical bordetellae are comprised of three subspecies that differ from broad to very limited host specificity. Although several lineages appear to have specialized to particular host species, most retain the ability to colonize and grow in mice, providing a powerful common experimental model to study their differences. One of the subspecies, Bordetella parapertussis, is composed of two distinct clades that have specialized to different hosts: one to humans (Bpphu), and the other to sheep (Bppov). While Bpphu and the other classical bordetellae can efficiently colonize mice, Bppov strains are severely defective in their ability to colonize the murine respiratory tract. Bppov genomic analysis did not reveal the loss of adherence genes, but substantial mutations and deletions of multiple genes involved in the production of O-antigen, which is required to prevent complement deposition on B. bronchiseptica and Bpphu strains. Bppov lacks O-antigen and, like O-antigen mutants of other bordetellae, is highly sensitive to murine complement-mediated killing in vitro. Based on these results, we hypothesized that Bppov failed to colonize mice because of its sensitivity to murine complement. Consistent with this, the Bppov defect in the colonization of wild type mice was not observed in mice lacking the central complement component C3. Furthermore, Bppov strains were highly susceptible to killing by murine complement, but not by sheep complement. These data demonstrate that the failure of Bppov to colonize mice is due to sensitivity to murine, but not sheep, complement, providing a mechanistic example of how specialization that accompanies expansion in one host can limit host range.
The Virtual Skeleton Database: An Open Access Repository for Biomedical Research and Collaboration (2013)

The VSD is a novel system for scientific collaboration for the medical image community with a data-centric concept and semantically driven search option for anatomical structures. The repository has been proven to be a useful tool for collaborative model building, as a resource for biomechanical population studies, or to enhance segmentation algorithms.
Piezoelectricity in crystallizing ferroelectric polymers: Poly(vinylidene fluoride) and its copolymers (A review) (2003)

The piezoelectricity observed in poly(vinylidene fluoride) (PVDF) and its copolymers involves three components that are associated with the presence of at least two phases (crystalline and amorphous) in the polymer structure. The main contributions to the phenomenon observed are made by the size effect and electrostriction, which are related to each other. These contributions manifest themselves through the mechanism of strain-induced reversible transformations of a number of domains of the anisotropic amorphous phase into the crystalline state under the action of mechanical or electrical fields. With due regard for different packings of chains in the amorphous and crystalline phases, this mechanism accounts for the large Poisson ratios μ31 obtained for textured films of flexible-chain crystallizing polymers. The dependence of the piezoelectric coefficient d 32 on the static stress in textured films is governed by the change in the fraction of the crystalline phase due to strong anisotropy of the elastic constants in the film plane. It is shown that the shear deformations of polymers are characterized by a strong piezoelectric response. The specific features revealed in the piezoelectric effect under bending deformations are described for films with an inhomogeneous distribution of polarization over the cross section. The general regularities of the electrostriction in the polymers and inorganic relaxor ferroelectrics studied are considered.
The Wind Band; Its Literature and Technique (1962)

A definitive study of bands. It provides histories of their European and American origins, as well as discussing contemporary bands, their technical problems and repertoire. It also makes practical suggestions for improving band performance.
All-Optical Signal Processing Based on Self-Induced Polarization Control in Optical Fibers (2015)

In this contribution, we review our recent progress on the all-optical control of the state-of-polarization of light in optical fibers upon propagation in a system called Omnipolarizer. More precisely, in this device we exploit the unexpected capability of light to self-organize its own state-of-polarization, upon propagation in optical fibers, into universal and environmentally robust states. The underlying physical mechanism consists in a nonlinear cross-polarization feedback interaction between an arbitrary polarized incident signal and its own counter-propagating replica generated at the fiber end by means of a reflective element. Depending on the power ratio between the two waves, e.g., the reflective coefficient, this nonlinear self-repolarization phenomenon offers a rich variety of dynamics for which we have highlighted three main working regimes identified by first a bistable operating regime, a polarization alignment process as well as a genuine chaotic behavior. We have fully characterized these three operating regimes with an excellent agreement between numerical and experimental results. Moreover, beyond the fundamental aspect of these first studies, we have then exploited this self-induced repolarization phenomenon in order to implement several proof-of-principles for all-optical signal processing. In particular, we have successfully demonstrated the spontaneous repolarization of a 10-Gb/s return-to-zero optical signal without noticeable impairments. The bistability and associated hysteresis properties of the Omnipolarizer have been also exploited to implement an optical flip-flop memory as well as a 10-Gb/s polarization-based data packet router. Finally, we have taken advantage of the chaotic dynamics of our device to demonstrate an all-optical scrambler enabling truly chaotic polarization diversity for 10-Gb/s on/off keying wavelength division multiplexing applications.