gebhart/patrepeval huggingface dataset:
Morphology Control of Mesoporous Silica Particles (2007)

We demonstrate morphology dependence of mesoporous silica synthesized in acidic condition via the control of silica hydrolysis and condensation at 4 °C under quiescent acidic condition, and without using any organic cosolvents. Tetramethyl orthosilicates (TMOS) is used as a silica source and cetyltrimethylammonium chloride (CTAC) as the structure directing agent (SDA). Straight fibers of different aspect ratio with pore channels aligned parallel to the fiber axis are synthesized by varying TMOS from the sols of molar compositions 0.17−0.32TMOS:0.22CTAC:9HCl:100H2O. Curved morphologies such as discoids and spheres are prepared by controlling acidity in the sols of molar compositions 0.17TMOS:0.22CTAC:14−16HCl:100H2O. The mesoporous silica particles show BET surface area of 1100−1400 cm3/g, and the mesopore diameter and mesopore volume are in the range of 2.2−2.6 nm and 0.6−0.8 cm3/g, respectively.
Numerical simulation of the biomechanical behaviour of multi-rooted teeth (2005)

The elastic properties of the periodontal ligament (PDL) in eight multi-rooted teeth were examined in a combined experimental and numerical study in six minipigs. The initial tooth movement of the mandibular primary molars surrounded by the periodontium was registered three-dimensionally (3D) in an optomechanical measuring system. The dissections were then embedded in resin and cut in transverse sections. Based on these sections, 3D finite element (FE) models were constructed and numerically loaded with the same force systems as used in the experiment. The material behaviour of the PDL registered in the experiment was non-linear and could be approximated with a bilinear parameter set consisting of two Young's moduli, E1 and E2, and one ultimate strain, epsilon12, separating both elastic regimes. When a deficient congruence existed between the experimental and numerical force/deflection curves the material parameters were varied to obtain a satisfactory congruence. The material behaviour determined for these specimens delivered mean values of E1 = 0.05 MPa, E2 = 0.18 MPa and epsilon12 = 6.4 per cent for the elastic behaviour of the multi-rooted minipig teeth. There was no significant difference in the material parameters determined for specimens with two, four or six roots. The results were in close agreement with the material parameters of the PDL, determined in previous investigations of single-rooted human and pig teeth.
Error resilient video coding via weighted distortion (2009)

Conventional rate-distortion (RD) optimized video coding is formulated for an error-free environment. Special considerations have to be made when transmitting video in lossy networks. In this paper we demonstrate a novel method of weighting the distortion used for mode decisions and motion estimation in H.264. By determining an appropriate weighting factor, motion vectors are biased towards macroblocks (MB) that have less influence on the motion propagation path and mode decisions are made considering a MB's future impact. We therefore propose tracking the influence that each macroblock has along the motion propagation path to determine the weights. Considerable performance improvements are unveiled in comparison with state of the art robust video schemes.
Mapping of a cell-binding domain in the cell adhesion molecule gp80 of Dictyostelium discoideum. (1988)

At the aggregation stage of Dictyostelium discoideum development, a cell surface glycoprotein of Mr 80,000 (gp80) has been found to mediate the EDTA-resistant type of cell-cell adhesion via homophilic interaction (Siu, C.-H., A. Cho, and A. H. C. Choi. 1987. J. Cell Biol. 105:2523-2533). To investigate the structure-function relationships of gp80, we have isolated full length cDNA clones for gp80 and determined the DNA sequence. The deduced structure of gp80 showed three major domains. An amino-terminal globular domain composed of the bulk of the protein is supported by a short stalk region, which is followed by a membrane anchor at the carboxy terminus. Structural analysis suggested that the cell-binding domain of gp80 resides within the globular domain near the amino terminus. To investigate the relationship of the cell-binding activity to this region of the polypeptide, three protein A/gp80 (PA80) gene fusions were constructed using the expression vector pRIT2T. These PA80 fusion proteins were assayed for their ability to bind to aggregation stage cells. Binding of 125I-labeled fusion proteins PA80I (containing the Val123 to Ile514 fragment of gp80) and PA80II (Val123 to Ala258) was dosage dependent and could be inhibited by precoating cells with the cell cohesion-blocking mAb 80L5C4. On the other hand, there was no appreciable binding of PA80III (Ile174 to Ile514) to cells. Reassociation of cells was significantly inhibited in the presence of PA80I or PA80II. In addition, 125I-labeled PA80II exhibited homophilic interaction with immobilized PA80I, PA80II, or gp80. The results of these studies lead to the mapping of a cell-binding domain in the region between Val123 and Leu173 of gp80 and provide direct evidence that the cell-binding activity of gp80 resides in the protein moiety.
The Multifaceted Role of Curcumin in Cancer Prevention and Treatment (2015)

Despite significant advances in treatment modalities over the last decade, neither the incidence of the disease nor the mortality due to cancer has altered in the last thirty years. Available anti-cancer drugs exhibit limited efficacy, associated with severe side effects, and are also expensive. Thus identification of pharmacological agents that do not have these disadvantages is required. Curcumin, a polyphenolic compound derived from turmeric (Curcumin longa), is one such agent that has been extensively studied over the last three to four decades for its potential anti-inflammatory and/or anti-cancer effects. Curcumin has been found to suppress initiation, progression, and metastasis of a variety of tumors. These anti-cancer effects are predominantly mediated through its negative regulation of various transcription factors, growth factors, inflammatory cytokines, protein kinases, and other oncogenic molecules. It also abrogates proliferation of cancer cells by arresting them at different phases of the cell cycle and/or by inducing their apoptosis. The current review focuses on the diverse molecular targets modulated by curcumin that contribute to its efficacy against various human cancers.
Chemical Modifications in Aggregates of Recombinant Human Insulin Induced by Metal-Catalyzed Oxidation: Covalent Cross-Linking via Michael Addition to Tyrosine Oxidation Products (2012)

MCO of insulin leads to covalent aggregation through cross-linking via Michael addition to tyrosine oxidation products.
Foam insulation gets first reeled installation off Australia (1992)

Development in 1989 of Seahorse and Tarwhine fields in the Bass Strait, offshore Australia, promoted the first reeled installation of the thermally insulated pipeline system known as pipe-in-pipe (PIP). This paper reports that this system consists of an inner steel pipe coated with high-density polyurethane (HDPU) foam inside an outer steel carrier pipe. The offshore lines for which PIP was finally chosen are 7 and 10.8 miles, respectively, connecting the Barracouta offshore platform and subsea wellheads at each field location. Several alternative coating systems were evaluated, as report in Part 1 of this series. This conclusion chronicles coating application and shore fabrication of PIP for this project.
Induction of monocytic cell adherence to matrix-bound fibronectin by phorbol ester. (1992)

The inflammatory response requires the localization of monocytic cells to sites of tissue injury through adherence to extracellular matrix molecules such as fibronectin (Fn), a nonimmune opsonin, which binds to collagen, fibrin, heparin and cell surfaces. Adherence to this molecule of two myeloid cell lines differing in their stage of differentiation, was studied. In the baseline state, U937 monocytic cells bound specifically to matrix-bound Fn, while HL-60 promyelocytic cells bound minimally. Exposure to Phorbol myristate acetate (PMA) dramatically increased binding of both U937 and HL-60 cells to Fn with plateau effects at 10 ng/ml for both cell lines and at 30 and 60 minutes for U937 and HL-60, respectively. Treatment with metabolic inhibitors suggests that PMA stimulation depends at least in part on intact energy metabolism, protein synthesis and cytoskeletal components. This system should help elucidate the early molecular and biochemical events involved in monocyte adherence to the extracellular matrix.
Both Strands of siRNA Have Potential to Guide Posttranscriptional Gene Silencing in Mammalian Cells (2009)

Despite the widespread application of RNA interference (RNAi) as a research tool for diverse purposes, the key step of strand selection of siRNAs during the formation of RNA-induced silencing complex (RISC) remains poorly understood. Here, using siRNAs targeted to the complementary region of Survivin and the effector protease receptor 1 (EPR-1), we show that both strands of the siRNA duplex can find their target mRNA and are equally eligible for assembly into Argonaute 2 (Ago2) of RISC in HEK293 cells. Transfection of the synthetic siRNA duplexes with different thermodynamic profiles or short hairpin RNA (shRNA) vectors that generate double-stranded RNAs (dsRNAs), permitting processing specifically from either the 5' or 3' end of the incipient siRNA, results in the degradation of the respective target mRNAs of either strand of the siRNA duplex with comparable efficiencies. Thus, while most RNAi reactions may follow the thermodynamic asymmetry rule in strand selection, our study suggests an exceptional mode for certain siRNAs in which both strands of the duplex are competent in sponsoring RNAi, and implies additional factors that might dictate the RNAi targets.
Characterization of a variable number tandem repeat region in the thiopurine S-methyltransferase gene promoter. (1999)

Characterization of the genetic polymorphism of thiopurine S-methyltransferase enzyme (TPMT; EC 2.1.1.67) is required because of its clinical importance for patients exposed to thiopurine drugs. A number of point mutations have already been characterized in exons and introns of the TPMT gene. Here we report the identification of a polymorphic locus within the promoter region of the gene. This polymorphism was detected by polymerase chain reaction - single strand conformation polymorphism analysis of DNA samples from 54 unrelated European individuals. A total of five alleles with length variations were distinguished through the 5'-flanking region involved in the TPMT gene expression. Sequence analysis revealed that these variations were due to a variable number of tandem repeats (VNTR), ranging from four to eight repeats. Each repeat consists of 17 or 18 bp units and contains putative binding sites for transcription factors. The most frequent alleles harbour four or five tandem repeats, a heterozygosity rate of 0.44 was calculated, and a stable Mendelian inheritance of alleles was demonstrated. Analysis of the effect of each VNTR allele on promoter activity of a reporter gene was further performed in various cell lines by transient transfection assay. A modulatory effect of VNTR alleles was observed in vitro, but the repeat polymorphism did not display a significative role in TPMT gene regulation in vivo. Further studies need to be carried out to support the hypothesis that VNTR may contribute to the large interindividual variations of TPMT activity.
Data Structures & Other Objects Using Java (1998)

The Phases of Software Development. Specification, Design, Implementation. Running Time Analysis. Testing and Debugging. Abstract Data Types and Java Classes. Classes and Their Members. Using a Class. Packages. Parameters, Equals Methods, and Clones. Collection Classes. A Review of Java Arrays. An ADT for a Bag of Integers. Programming Project: The Sequence ADT. Applets for Interactive Testing. Linked Lists. Fundamentals of Linked Lists. Methods for Manipulating Nodes. Manipulating an Entire Linked List. The Bag ADT with a Linked List. Programming Project: The Sequence ADT with a Linked List. Arrays vs. Linked Lists vs. Doubly Linked Lists. Java Objects and Iterators. Java's Object Type. A Bag of Objects. JCL Collections and Nodes of Objects. Iterators. Stacks. Introduction to Stacks. Stack Applications. Implementations of the Stack ADT. More Complex Stack Applications. Queues. Introduction to Queues. Queue Applications. Implementations of the Queue. ADT. Priority Queues. Recursive Thinking. Recursive Methods. Studies of Recursion: Fractals and Mazes. Reasoning about Recursion. Trees. Introduction to Trees. Tree Representations. A Class for Binary Tree Nodes. Tree Traversals. Binary Search Trees. Tree Projects. Heaps. B-Trees. Trees, Logs, and Time Analysis. Searching. Serial Search and Binary Search. Open-Address Hashing. Using Java's Hashtable Class. Chained Hashing. Time Analysis of Hashing. Sorting. Quadratic Sorting Algorithms. Recursive Sorting Algorithms. An O(N LOG N) Algorithm Using a Heap. Software Reuse with Extended Classes. Extended Classes. Simulation of an Ecosystem. Using Extended Classes for ADTs. Graphs. Graph Definitions. Graph Implementations. Graph Traversals. Path Algorithms. Appendices. Java's Primitive Types and Arithmetic Overflow. Java Input. Throwing and Catching Java Exceptions. Java's Vector and Hashtable. A Class for Nodes in a Linked List. A Class for a Bag of Objects. Further Big-O Notation. Javadoc. 0201357445T04062001
Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling (2012)

The human multidrug and toxin extrusion (MATE) transporter 1 contributes to the tissue distribution and excretion of many drugs. Inhibition of MATE1 may result in potential drug-drug interactions (DDIs) and alterations in drug exposure and accumulation in various tissues. The primary goals of this project were to identify MATE1 inhibitors with clinical importance or in vitro utility and to elucidate the physicochemical properties that differ between MATE1 and OCT2 inhibitors. Using a fluorescence assay of ASP(+) uptake in cells stably expressing MATE1, over 900 prescription drugs were screened and 84 potential MATE1 inhibitors were found. We identified several MATE1 selective inhibitors including four FDA-approved medications that may be clinically relevant MATE1 inhibitors and could cause a clinical DDI. In parallel, a QSAR model identified distinct molecular properties of MATE1 versus OCT2 inhibitors and was used to screen the DrugBank in silico library for new hits in a larger chemical space.
Applications of chemical-looping combustion with capture of CO2 (2001)

Chemical-looping combustion (CLC) is a combustion technology with inherent separation of the greenhouse gas CO2. The technique involves the use of a metal oxide as an oxygen carrier which transfers oxygen from the combustion air to the fuel. Hence the direct contact between fuel and combustion air is avoided. Subsequently, the products from combustion, e.g. carbon dioxide and water, will be kept separate from the rest of the flue gases, e.g. nitrogen and any remaining oxygen. Two reactors in the form of interconnected fluidized beds are used in the process: i) a fuel reactor where the metal oxide is reduced by reaction with the fuel, and ii) an air reactor where the reduced metal oxide from the fuel reactor is oxidized with air. The outlet gas from the fuel reactor consists of CO2 and H2O, while the outlet gas stream from the air reactor contains only N2 and some unused O2. The net chemical reaction over the two reactors is the same as for normal combustion with the same amount of heat released, but with the important difference that carbon dioxide is inherently separated from nitrogen, and no extra energy is needed for this separation. This is in contrast to known techniques for separating carbon dioxide from flue gas, where large amounts of energy and
Content fingerprinting from an industry perspective (2009)

Content recognition technology, particularly digital fingerprinting of audio and video content, has important applications in the distribution of movies and television programming on the Internet. However, the identification process is complex as distributed content is often substantially altered prior to distribution through processes such as cropping, shape transformations, noise, signal distortion and transcoding that make recognition difficult. Fingerprinting has emerged as a robust and general approach to content identification. MovieLabs and the Motion Picture Association of America have been conducting tests of various fingerprint algorithms against real-world content. Our findings indicate that the best algorithms can achieve match accuracy greater than 98% with a 0% misrecognition (false positive) rate against severely transformed content. This paper describes applications of content recognition, fingerprinting, criteria and methods for evaluating fingerprinting, and describes our fingerprint testing.
Adiponectin and Leptin in Maternal Serum, Cord Blood, and Breast Milk (2006)

Concentrations of adiponectin and leptin vary strongly in maternal serum, cord blood, and breast milk, with only moderate correlations between both adipokines in maternal serum and breast milk. The health implications of these patterns warrant further investigation.
A high performance CBiCMOS with novel self-aligned vertical PNP transistors (2002)

This paper describes a vertical PNP transistor with a novel self-aligned structure and a complementary BiCMOS process which makes use of it. The PNP's emitter electrode is formed at the same fabrication step as that of a self-aligned NPN's base electrode, and the base electrode is formed at the same fabrication step as that of the self-aligned NPN's emitter electrode. The PNPs have been fabricated adding only one photo-mask and one doping step to the BiCMOS processes. The maximum cutoff frequency or PNP and NPN transistors are 4.2 GHz and 20 GHz, respectively. The MOS transistors are compatible with simple CMOS devices.
Tunable diode laser systems for trace gas monitoring (1991)

Tunable diode laser absorption spectrometry can provide unequivocal identification of many of the trace gases of atmospheric interest with rapid response and high sensitivity. Instrumentation is described which can measure trace gases with the required sensitivity, specificity and response time dictated by widely differing environments including ambient air, from both mobile laboratories and aircraft, smog chambers and in exhaust gas emissions. Representative examples are discussed of applications to measurements of ambient air under clean and highly polluted conditions, CH4 fluxes from airborne and ground based platforms and combustion gases in diluted and undiluted exhaust from Diesel and automobile engines.
Utilization of bagasse in new composite building materials (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUtilization of bagasse in new composite building materialsIval O. Salyer and Arthur M. UsmaniCite this: Ind. Eng. Chem. Prod. Res. Dev. 1982, 21, 1, 17–23Publication Date (Print):March 1, 1982Publication History Published online1 May 2002Published inissue 1 March 1982https://pubs.acs.org/doi/10.1021/i300005a004https://doi.org/10.1021/i300005a004research-articleACS PublicationsRequest reuse permissionsArticle Views278Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Cavitation in Liquid Helium (1966)

Ultrasonic cavitation has been induced in liquid helium over the temperature range 1.2°–4.2°K, using plane and cylindrical standing-wave systems at 90 and 46 kc/sec, respectively. The threshold for cavitation noise measured with the plane wave system is only of the order of millibars of root-mean-square pressure amplitude, rises sharply near the λ point, and is insensitive to variations of static pressure, addition of solid air or imposition of electric fields. Visible cavtation, obtained most readily with the cylindrical standing wave changes dramatically in nature in different temperature regimes. The results are compared with those obtained using “hyrodynamic” techniques, and the theoretical implications of the work are briefly discussed.
Improving the Table Boundary Detection in PDFs by Fixing the Sequence Error of the Sparse Lines (2009)

As the rapid growth of PDF documents, recognizing the document structure and components are useful for document storage, classification and retrieval. Table, a ubiquitous document component, becomes an important information source. Accurately detecting the table boundary plays a crucial role for many applications, e.g., the increasing demand on the table data search. Rather than converting PDFs to image or HTML and then processing with other techniques (e.g., OCR), extracting and analyzing texts from PDFs directly is easy and accurate. However, text extraction tools face a common problem: text sequence error. In this paper, we propose two algorithms to recover the sequence of extracted sparse lines, which improve the table content collection. The experimental results show the comparison of the performance of both algorithms, and demonstrate the effectiveness of text sequence recovering for the table boundary detection.
Invariant distances and metrics in complex analysis–-revisited (2005)

4 25 &6 87 91 (@ 9A CB D6 E% (' GF H# &% 9' IB C5 8@ P4 "4 2Q SR UT 2) 5 &B D) 2 V# XW YB C6 `# a) 2 (b G' I6 c) 2 (F ed f' g# E5 &B Db I6 cB C ih 4 p q7 rA C' Is t 9) 2A vu 36 EB D6 xw &! yB D f % 9B Cb % e# &% (' gu fF (B C6 Eb G1 (6 E6 E' IF # &% (' q6 `# a) # &' 4 2 ) y) B C5 &6 YB C e# &% (' F (4 p ) 2B D 0 f# &% (' p ' G) 2 V# &B Dp ' ! 6 E4 p ' Y4 7 ' I U1 (' G6 `# &B C4 (6 p ' I U# &B C4 (' GF B C # &% (' c@ P4 "4 2Q % 9) GT V' c@ P' G'
P‐25: A LCOS Microdisplay Driver with Frame Buffering Pixels (2002)

Abstract An 8‐bit LCOS microdisplay driver for projection display has been designed and fabricated using AMI 0.5 um double‐poly, triple‐level metal CMOS process. The driver includes new frame buffer pixels which presents optimized optical characteristics for Field Sequential Color technique, and a mixed mode grayscale method which implements distinct 256 gray levels per color with a simple driver architecture. The voltage at the frame buffer pixels varies from 0 to 4.25 volts. The new frame buffer pixels enables a LCOS microdisplay to improve brightness without the loss of contrast ratio.