gebhart/patrepeval huggingface dataset:
Deep Venous Thrombosis and ABO Blood Group Are Unrelated in Trauma Patients (2002)

These data do not support a clinically relevant association between blood type and DVT in trauma patients. Injury-associated derangements of coagulation may be more important than any hypercoagulability related to blood type in this population.
ENZYME LOCALIZATION DURING MELANOGENESIS (1969)

The DOPA-reaction was used to identify tyrosinase in the nucleus and cytoplasm of the neural crest melanoblast of Taricha torosa, the California newt. In this urodele there is a nuclear DOPA-positive response during the normal embryonic development from the late blastula stage to the nucleus of the early melanocyte. During the gastrula stages, all nuclei of this newt are DOPA-positive. This positive nuclear response fades away after the formation of the neural crest, save in the melanoblasts. The only cells that give a positive DOPA marking in the cytoplasm are the melanoblasts. This cytoplasmic reaction appears while the melanoblast nucleus still gives a DOPA-positive reaction. Tyrosinase activity, as marked by unlabeled DOPA, has ceased in the fully mature melanocyte. The red nuclei, seen in some of the animals in the maturing melanocyte and adjacent tissues, may be in the hallachrome stage of melanin formation. There is a diffuse distribution of DOPA reactivity in the resting nucleus, and an adherence of the DOPA-marking in the region of the dividing chromosomes in the mitosis of DOPA-positive nuclei of the melanoblast. These observations suggest that tyrosinase may be among the chromosomally bound enzymes of the chromatin space.
Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process (2008)

Industrial ethanol fermentation is a non-sterile process and contaminant microorganisms can lead to a decrease in industrial productivity and significant economic loss. Nowadays, some distilleries in Northeastern Brazil deal with bacterial contamination by decreasing must pH and adding bactericides. Alternatively, contamination can be challenged by adding a pure batch of Saccharomyces cerevisiae-a time-consuming and costly process. A better strategy might involve the development of a fungicide that kills contaminant yeasts while preserving S. cerevisiae cells. Here, we show that polyhexamethyl biguanide (PHMB) inhibits and kills the most important contaminant yeasts detected in the distilleries of Northeastern Brazil without affecting the cell viability and fermentation capacity of S. cerevisiae. Moreover, some physiological data suggest that PHMB acts through interaction with the yeast membrane. These results support the development of a new strategy for controlling contaminant yeast population whilst keeping industrial yields high.
YakA, a protein kinase required for the transition from growth to development in <i>Dictyostelium</i> (1998)

When Dictyostelium cells starve they arrest their growth and induce the expression of genes necessary for development. We have identified and characterized a protein kinase, YakA, that is essential for the proper regulation of both events. Amino acid sequence and functional similarities indicate that YakA is a homolog of Yak1p, a growth-regulating protein kinase in S. cerevisiae. Purified YakA expressed in E. coli is able to phosphorylate myelin basic protein. YakA-null cells are smaller and their cell cycle is accelerated relative to wild-type cells. When starved, YakA-null cells fail to decrease the expression of the growth-stage gene cprD, and do not induce the expression of genes required for the earliest stages of development. YakA mRNA levels increase during exponential growth and reach a maximum at the point of starvation, consistent with a role in mediating starvation responses. YakA mRNA also accumulates when cells are grown in medium conditioned by cells grown to high density, suggesting that yakA expression is under the control of an extracellular signal that accumulates during growth. Expression of yakA from a conditional promoter causes cell-cycle arrest in nutrient-rich medium and promotes developmental events, such as the expression of genes required for cAMP signaling. YakA appears to regulate the transition from growth to development in Dictyostelium.
Quenching and reduction of photoexcited benzophenone by thioethers and mercaptans (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuenching and reduction of photoexcited benzophenone by thioethers and mercaptansJoseph B. Guttenplan and Saul G. CohenCite this: J. Org. Chem. 1973, 38, 11, 2001–2007Publication Date (Print):June 1, 1973Publication History Published online1 May 2002Published inissue 1 June 1973https://pubs.acs.org/doi/10.1021/jo00951a007https://doi.org/10.1021/jo00951a007research-articleACS PublicationsRequest reuse permissionsArticle Views230Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Measurement Study of Multi-party Video Conferencing (2010)

More and more free multi-party video conferencing applications are readily available over the Internet and both Server-to-Client (S/C) or Peer-to-Peer (P2P) technologies are used. Investigating their mechanisms, analyzing their system performance, and measuring their quality are important objectives for researchers, developers and end users. In this paper, we take four representative video conferencing applications and reveal their characteristics and different aspects of Quality of Experience. Based on our observations and analysis, we recommend to incorporate the following aspects when designing video conferencing applications: 1) Traffic load control/balancing algorithms to better use the limited bandwidth resources and to have a stable conversation; 2) Use traffic shaping policy or adaptively re-encode streams in real time to limit the overall traffic. This work is, to our knowledge, the first measurement work to study and compare mechanisms and performance of existing free multi-party video conferencing systems.
ChemInform Abstract: SYNTHESIS OF OPTICALLY ACTIVE NATURAL CAROTENOIDS AND STRUCTURALLY RELATED COMPOUNDS. I. SYNTHESIS OF THE CHIRAL KEY COMPOUND (4R,6R)‐4‐HYDROXY‐2,2,6‐TRIMETHYLCYCLOHEXANONE (1976)

Abstract Die technische Synthese der Titelverbindung (III), einer idealen Schlüsselverbindung für die Synthese von optisch aktiven hydroxylierten Carotinoiden ( ;z.B. Zeaxanthin oder Cryptoxanthin), erfolgt ausgehend von Oxoisophoron (I), dessen Doppelbindung fennentativ unter Bildung des Dions (II) reduziert wird (eingehende Untersuchung zur Optimierung der Reaktion) . Die nachfolgende chemische Reduktion in gewünschter Richtung unter Bildung von (III) gelingt durch Hydrierung von (II) mit Raney‐Ni oder mit Triisobutyl‐Al (TIBA); das unerwünschte Isomere (IV) entsteht jeweils nur als Nebenprodukt.
S <sup>2</sup> Connector Versus Suture (2006)

In the porcine model, the connector rapidly and consistently produced high-quality anastomoses that fully met current standards on patency and function. Unconventional aspects like a noncompliant intraluminal ring and a side-to-side to end-to-side converted configuration did not interfere with favorable anastomosis remodeling. These findings shed a new light on the anatomical prerequisites for anastomosis patency.
Chemical sensors (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemical sensorsJiri. Janata and Andras. BezeghCite this: Anal. Chem. 1988, 60, 12, 62–74Publication Date (Print):June 15, 1988Publication History Published online1 May 2002Published inissue 15 June 1988https://pubs.acs.org/doi/10.1021/ac00163a004https://doi.org/10.1021/ac00163a004research-articleACS PublicationsRequest reuse permissionsArticle Views910Altmetric-Citations179LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Theoretical Study on Monoligated Pd-Catalyzed Cross-Coupling Reactions of Aryl Chlorides and Bromides (2008)

The mechanism of oxidative addition of aryl halides to Pd(PR3)2 (R = Me, Et, iPr, tBu, Ph) was investigated by using density functional theory methods enhanced with a polarized continuum solvation model. Different reaction pathways were discussed on the basis of Gibbs free-energy profiles in a tetrahydrofuran solution. The calculations indicated that monophosphine PdPR3 was catalytically more active than bisphosphine Pd(PR3)2 for oxidative addition. However, among different PR3 ligands (R = Me, Et, iPr, tBu, Ph), the free-energy barriers for oxidative addition to PdPR3 did not change significantly (i.e., less than 2 kcal/mol). This gave rise to an important question: why was P(t-Bu)3 the only catalytically active ligand toward aryl chlorides among the above five ligands? It was proposed on the basis of the calculated data that the difference of the dissociation energies from PdL2 to PdL and L (L = ligand) between the various PR3 ligands dictated their dissimilar reactivity in oxidative addition.
Noninvasive Imaging of PSMA in Prostate Tumors with <sup>89</sup>Zr-Labeled huJ591 Engineered Antibody Fragments: The Faster Alternatives (2014)

Engineered antibody fragments offer faster delivery with retained tumor specificity and rapid clearance from nontumor tissues. Here, we demonstrate that positron emission tomography (PET) based detection of prostate specific membrane antigen (PSMA) in prostatic tumor models using engineered bivalent antibodies built on single chain fragments (scFv) derived from the intact antibody, huJ591, offers similar tumor delineating properties but with the advantage of rapid targeting and imaging. (89)Zr-radiolabeled huJ591 scFv (dimeric scFv-CH3; (89)Zr-Mb) and cysteine diabodies (dimeric scFv; (89)Zr-Cys-Db) demonstrated internalization and similar Kds (∼2 nM) compared to (89)Zr-huJ591 in PSMA(+) cells. Tissue distribution assays established the specificities of both (89)Zr-Mb and (89)Zr-Cys-Db for PSMA(+) xenografts (6.2 ± 2.5% ID/g and 10.2 ± 3.4% ID/g at 12 h p.i. respectively), while minimal accumulation in PSMA(-) tumors was observed. From the PET images, (89)Zr-Mb and (89)Zr-Cys-Db exhibited faster blood clearance than the parent huJ591 while tumor-to-muscle ratios for all probes show comparable values across all time points. Ex vivo autoradiography and histology assessed the distribution of the probes within the tumor. Imaging PSMA-expressing prostate tumors with smaller antibody fragments offers rapid tumor accumulation and accelerated clearance; hence, shortened wait periods between tracer administration and high-contrast tumor imaging and lower dose-related toxicity are potentially realized.
Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia (1993)

Organotypic culture of embryonic rat lumbar spinal cord and dorsal root ganglia has been used to demonstrate an inhibitory effect of ventral spinal cord on neurite growth from dorsal root ganglion explants. When dorsal root ganglion explants from 14-15 day old embryos were cultured alone or in close proximity to a dorsal cord explant, the pattern of dorsal root ganglion neurite outgrowth was typically radial. However, when E14-15 dorsal root ganglion explants were cocultured for 22-24 hours in proximity to a ventral spinal cord explant from the same embryo, few, if any, dorsal root ganglion neurites grew in the direction of the ventral cord explant. This inhibitory effect appeared to be developmentally regulated; it was diminished or absent in cocultures prepared from 18 day old embryos. In contrast, in cocultures of dorsal cord and ventral cord explants from E14-15 embryos, dorsal cord neurites grew abundantly toward the ventral cord explant suggesting that the inhibition is not likely to be due to a nonspecific neurotoxic effect and that the activity responsible selectively inhibits dorsal root ganglion neurite outgrowth. We conclude that a diffusible, primary afferent inhibitory factor(s) produced by embryonic ventral horn may be responsible for the inhibition. Our results are discussed with respect to the possible involvement of inhibition in the normal development of primary afferent innervation of the spinal cord.
Topical Phenytoin in Diabetic Foot Ulcers (1991)

Phenytoin appears to be useful as a topical agent in promoting the healing of diabetic foot ulcers.
Surface studies of albumin immobilized onto PE and PVC films (1997)

The aim of this study is to evaluate the thrombogenic behaviour of the low density polyethylene and poly(vinyl chloride) modified by radiation-grafting technique. After copolymerization with acrylic acid by gamma-rays from a 60Co source, BSA was immobilized onto functionalized graft copolymers. The biological interaction between these materials and blood was studies by in vitro methods. The BSA immobilization effectively suppressed the adhesion and activation of platelets when it contacted whole blood.
RFID tags : Big Brother in small pachkages (2003)

You should become familiar with RFID technology because you'll be hearing much more about it soon. Retailers adore the concept, and CNET News.com's own Alorie Gilbert wrote last week about how Wal-Mart and the U.K.-based grocery chain Tesco are starting to install smart shelves with networked RFID readers. In what will become the largest test of the technology, consumer goods giant Gillette recently said it would purchase 500 million RFID tags from Alien Technology of Morgan Hill, Calif.
TURBINE ENGINE BLADING: - Manufacturing Technique and Fastening Methods (1948)

<div class="htmlview paragraph"><b>S</b>INCE we do not yet know just what loss in performance occurs as buckets, blades, and vanes vary from the ideal airfoil contour, the authors recommend that these parts be held to the ideal as closely as is commercially practicable.</div> <div class="htmlview paragraph">The British method of attaching the bucket by loosefit, fir-tree root is considered by them to be the best all around method developed to date.</div> <div class="htmlview paragraph">They call attention to the problems of large production welding of turbine wheel buckets, both from the manufacturing and the field replacement viewpoints and point out that remarkable progress has been made with high-temperature alloys, including their handling in production.</div> <div class="htmlview paragraph">They feel that the surface has hardly been scratched as to the future possibilities of engine design, alloys, and improved manufacturing methods for reduced cost and closer tolerances.</div>
Effect of Permeability on Foam-model parameters - An Integrated Approach from Coreflood Experiments through to Foam Diversion Calculations (2015)

Foam reservoir simulations commonly suffer from poor foam parameter definition which makes their predictions ambiguous. To reduce uncertainty in foam parameter estimation, extensive core-flood experiments under variable experimental and physical conditions are required. A principal physical property which can influence foam parameters is permeability. We present a set of steady-state foam-flood experimental data for four sandstones with different permeabilities, ranging between 6 and 1900 mD, and with similar porosity. We derive permeability-dependent foam parameters with two modelling approaches, those of Boeije and Rossen (2013) and a non-linear least-square minimization approach (Eftekhari et al., 2015). The two approaches can yield significantly different foam parameters. Thus we critically assess their ability in deriving reliable foam parameter estimates. In particular, the way the two approaches treat shear-thinning foam behavior and foam coalescence is discussed. The foam parameter set acquired from the latter approach is further used as input in foam diversion calculations: this serves to evaluate mobility predictions in non-communicating reservoir layers to the foam parameters. This study aims to provide a framework to integrate experimental work, modelling and simple qualitative diversion calculations to provide a background for the upscaling of foam studies, with particular focus to heterogeneous systems.
Italy’s national income (2014)

In the second half of 1950 the Italian Central Institute of Statistics published a special volume containing the results of an exhaustive investigation into the structure and recent trends of Italy’s national income. The present article describes and comments on the recapitulative data, pointing out the essential features of Italy’s national product and national income. The author calls attention to the war disturbances, the post-war recovery movement, the changes that have occurred since 1938 in the percentage weight of the several component items (private activities, public sector, indirect taxes, incomes from abroad and donations), and especially to the industrial and agricultural income. The statistical analysis is preceded by explanatory remarks as to clear up certain problems of method and definition. JEL: E01
Study of wavelength division multiplexing as a means of increasing the number of channels in multimode fiber optic communication links (1990)

A number of optical communication lines are now in use at the Kennedy Space Center (KSC) for the transmission of voice, computer data, and video signals. Presently, all of these channels utilize a single carrier wavelength centered near 1300 nm. The theoretical bandwidth of the fiber far exceeds the utilized capacity. Yet, practical considerations limit the usable bandwidth. The fibers have the capability of transmitting a multiplicity of signals simultaneously in each of two separate bands (1300 and 1550 nm). Thus, in principle, the number of transmission channels can be increased without installing new cable if some means of wavelength division multiplexing (WDM) can be utilized. The main goal of these experiments was to demonstrate that a factor of 2 increase in bandwidth utilization can share the same fiber in both a unidirectional configuration and a bidirectional mode of operation. Both signal and multimode fiber are installed at KSC. The great majority is multimode; therefore, this effort concentrated on multimode systems.
NONSURGICAL ASPECTS OF THE KIDNEY STONE PROBLEM (1939)

Our purpose in this paper is to report some observations which have been made at the Stone Clinic of the Massachusetts General Hospital and in the Research Laboratory since a previous brief report<sup>1</sup>in 1937. This paper is not meant to be a well balanced discussion of all the nonsurgical aspects of the kidney stone problem. The approach to the entire subject has remained fundamentally the same. It is based on the following major premise and its corollary: <h3>Premise.—</h3> A patient with urine of such composition that some crystalloid precipitates out of it is predisposed to the formation of a stone composed largely of the precipitated crystalloid (compare cystine stone in cystinuria, uric acid stone in gout and calcium phosphate or calcium oxalate stone in hyperparathyroidism). <h3>Corollary.—</h3> In a case in which there is a tendency for stones composed predominantly of a certain crystalloid to form, treatment should be
Recording calorimeter for the measurement of heats of wetting, mixing, or solution (1960)

A calorimeter has been designed for the measurement of heat liberations of less than 50 cal. Automatic temperature recording with variable amplification has been linked to the measuring thermocouples to produce a permanent record of temperature changes in the calorimeter. Magnetically operated stirring and reaction initiation (by bursting an evacuated bulb containing adsorbent or reagent) are employed. Electrical calibration is made for each system before and after bursting the bulb. The use of the calorimeter in measuring the heat of wetting of charcoal and the heat of mixing of water and methanol is demonstrated. Application of the calorimeter to other thermometric procedures within the mechanical limitations of the instrument is discussed.
Intelligent Assistant for Context-Aware Policies (2011)

Recent advancements in document handling tools have greatly simplified the tasks of reusing content and copying between secure and unsecure locations. As a result, intentional and unintentional data leaks are occurring more often and so posing a serious risk. To address this issue, context-aware policies have been introduced so that the policies pertain to the patterns of text contained in actual run-time content - as well as static document-level metadata with the aim of distinguishing different types of sensitive documents. Unlike traditional metadata based policies, context-aware policies do not need to have any overlap in their conditions for contradictions to occur, which makes it harder to create and manage coherent, ambiguity free sets of policies. We provide a novel Intelligent Modeling Assistant (IMA) that automatically deals with resolvable complications in modelling, while breaking tasks requiring manual intervention into a set of simple decisions. The IMA also helps the administrator to understand possible consequences of policies through sets of examples. Our implementation using constraint satisfaction technology is described.
Analog System-on-a-Chip with Application to Biosensors (2005)

This dissertation facilitates the design and fabrication of analog systems-on-a-chip (SoCs). In this work an analog SoC is developed with application to organic fluid analysis. The device contains a built-in self-test method for performing on-chip analysis of analog macros. The analog system-on-a-chip developed in this dissertation can be used to evaluate the properties of fluids for medical diagnoses. The research herein described covers the development of: analog SoC models, an improved set of chemical sensor arrays, a self-contained system-on-a-chip for the determination of fluid properties, and a method of performing on-chip testing of analog SoC sub-blocks.