gebhart/patrepeval huggingface dataset:
An integrated decision support system for diagnosing and managing patients with community-acquired pneumonia. (1999)

Decision support systems that integrate guidelines have become popular applications to reduce variation and deliver cost-effective care. However, adverse characteristics of decision support systems, such as additional and time-consuming data entry or manually identifying eligible patients, result in a "behavioral bottleneck" that prevents decision support systems to become part of the clinical routine. This paper describes the design and the implementation of an integrated decision support system that explores a novel approach for bypassing the behavioral bottleneck. The real-time decision support system does not require health care providers to enter additional data and consists of a diagnostic and a management component.
The steroid glycoside H.g.-12 from Hoodia gordonii activates the human bitter receptor TAS2R14 and induces CCK release from HuTu-80 cells (2010)

Steroid glycosides extracted from the succulent plant Hoodia gordonii are suggested to have appetite-suppressant effects both in animals and humans. Yet, the mechanisms underlying the putative satiety action of Hoodia steroid glycosides are not fully understood. We found that H.g.-12, a steroid glycoside purified from H. gordonii extract, initiated cholecystokinin (CCK) secretion both ex vivo in rat intestine and in vitro in the human enteroendocrine (EC) cell line HuTu-80. CCK is known to exert central effects on appetite suppression via the vagus nerve which afferents terminate in the gut wall. Recent data show that G protein-coupled receptors signaling bitter taste (T2Rs) are expressed in both rodent and human gastrointestinal tract. It was further demonstrated that bitter sensing is functional in mouse STC-1 EC cells and leads to CCK secretion via increased intracellular Ca²(+) concentrations. Based on the bitter taste of H. gordonii purified extracts, we assessed whether H.g.-12 could activate human bitter receptors. The steroid glycoside activated selectively TAS2R7 and TAS2R14, both heterologously expressed in HEK 293 cells. Removing an essential structural feature from the steroid glycoside inhibited H.g.-12-induced Ca²(+) increase in TAS2R14-expressing HEK cells and abolished H.g.-12-induced CCK secretion from human EC cells. Similarly, a nonspecific bitter receptor antagonist abolished H.g.-12-induced CCK secretion in HuTu-80 cells. These results point to a potential route of action by which components of Hoodia might influence appetite control. Our data also provide additional evidence that bitter taste-sensing mechanisms are coupled to hormone release from EC cells in the intestine. Moreover, we identified a natural agonist of TAS2R7 and TAS2R14 for further studies on the role of bitter receptors in satiety control and food intake.
Novel role for epidermal growth factor‐like domain 7 in metastasis of human hepatocellular carcinoma† (2009)

Our study suggests Egfl7 as a novel prognostic marker for metastasis of HCC and a potential therapeutic target.
Effects of Caffeine on the Absorption and Analgesic Efficacy of Paracetamol in Rats (1973)

Oral doses of caffeine (10, 50 or 100 mg/kg) given to rats together with paracetamol (200 mg/kg p.o.) inhibited paracetamol absorp tion and thus lowered the serum concentrations of paracetamol. This caf feine action was dose-dependent and similar to that on blood alcohol levels, as recently published by us. Delayed stomach emptying is very proba bly the main cause for the diminished absorption of orally given drugs in the presence of caffeine. Paracetamol analgesia was not decreased by caffeine, which, given alone (50 and 100 mg/kg), increased the pain threshold in rats. Only the lowest dose of caffeine (10 mg/kg), being itself ineffective, reduced paracetamol analgesia significantly.
Communication network analysis with COMNET 11.5 (1989)

COMNET II.5 is a general SIMSCRIPT II.5-based model for the performance analysis of circuit, message, or packet-switching networks. A variety of routing algorithms are built-in. After creating a network description with a convenient menu-driven editor, simulation follows immediately. There are no programming delays. Network operation is animated during the simulation. Reports show blocking probabilities, call queueing and packet delays, network throughput, link group utilization, and link group queue statistics. Some of the major enhancements that have been added to COMNET II.5 during the past year include capabilities for modeling multidestination messages, empirical probability distributions, flood routing, and access facilities. An access facility can be a point-to-point or multipoint line or a local area network.
Effect of Superabsorbent Polymer on the Properties of Concrete (2017)

Incorporating superabsorbent polymer (SAP), which has the abilities of absorption and desorption in concrete can achieve the effect of internal curing. The influences of the volume, particle size and ways of entrained water of SAP on the workability, compressive strength, shrinkage, carbonation resistance and chloride penetration resistance of concrete were analyzed through the macroscopic and microscopic test. The results show that pre-absorbed SAP can increase the slump of the mixture, but SAP without water absorption and pre-absorbed SAP with the deduction of internal curing water from mixing water can reduce the slump. The improvement effects of SAP on compressive strength of concrete increase gradually with the increase of age. Especially from 28 days, the compressive strength of concrete increases obviously. At later age, the compressive strengths of SAP concrete under natural curing environment exceed the strength of reference concrete under natural curing environment and nearly reach the strengths of reference concrete under standard curing environment. SAP effectively reduces the shrinkage of concrete, improves the concrete's abilities of carbonation resistance and chloride penetration resistance. The microscopic test results show that SAP can effectively improve the micro structure and make the pore structure refined. When SAP is added into concrete, the gel pores and small capillary pores are increased, the size of big capillary pores and air pores are reduced.
A 1V 16.9ppm/°C 250nA Switched-Capacitor CMOS Voltage Reference (2008)

We have developed a switched-capacitor CMOS voltage reference (SCVR). The circuit is shown in Fig. 24.3.2 and is composed of a low-power bias circuit [G. De Vita and G. iannacone, 2007], a core circuit and a switched-capacitor difference amplifier that is insensitive to op-amp offset voltage. The clock signals (phi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> , phi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , phi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ') are non-overlapping to prevent leakage. The core circuit supplies V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">gs1</sub> and V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">gs2</sub> to the switched-capacitor difference amplifier on phases phi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> and phi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , respectively. The difference amplifier then generates an output, which has a low TC, based on the gate-source voltage difference, AVGS.
Immunhistochemical expression of galectin-3 in cancer: a review of the literature (2011)

Galectin-3 is a β-galactoside-binding animal lectin that contains carbohydrate-recognition domains and displays multiple related functions. It has important roles in diverse biological events, such as embryogenesis, growth, cell adhesion, proliferation, differantiation, cell-cycle progression, apoptosis, mRNA splicing, and regulation of the immune system. Galectin-3 is expressed in various cells and tissues, such as activated macrophages, eosinophils, neutrophils, mast cells, epithelium of the gastrointestinal and respiratory tracts, kidneys and some sensory neurons, and is also involved in tumorigenesis, angiogenesis, and tumor metastasis. In this review of the literature, immunohistochemical Galectin-3 expression is investigated in numerous tumors and disorders of various organ systems.
Star couplers with gain using fiber amplifiers (1992)

The authors propose a novel technique for constructing large passive star couplers with gain using high-power erbium-doped fiber (EDF) amplifiers. In contrast to other proposed techniques where each output port of the coupler requires its own EDF amplifier, the proposed alternative requires few EDF amplifiers with sufficient output saturation power levels. When used in an FDM/WDM star network, the size of the coupler can be increased by a factor of m using m narrowband EDF amplifiers. Moreover, this alternative avoids coupling the pump-laser light through the star coupler itself, alleviating the requirement on designing large bandwidth couplers to accommodate the signal and the pump wavelengths.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Polymer Microwave Fibers: A New Approach That Blends Wireline, Optical, and Wireless Communication (2019)

The demand for data communication capacity keeps increasing. Applications ranging from wireless and hand-held mobile electronics to big data centers and backbone infrastructure are driving the need. With 5G technology being deployed, the common trend for high-speed wireless communication is to shift the operating frequency toward the millimeter-wave (mm-wave) spectrum (30-300 GHz) and exploit the highly available bandwidth. This shift is driven by the continuous improvement of bulk CMOS and packaging technologies that enable the full integration of mm-wave radios. Copper wireline technology also continues the trend toward multilevel and multitone modulation for high-speed, short-distance communication links. Copper cables, however, are often complex, expensive, and prone to electromagnetic interference (EMI). Moreover, the required equalization techniques are power hungry. Optical communication benefits from low-loss glass optical fibers (GOFs) with enormous bandwidths, enabling trans-Atlantic communication. This technology, however, requires micrometer alignment precision and costly optical-electrical conversion.
Development of Radio Aids to Air Navigation (1928)

The development of aircraft has reached a stage where further progress depends upon the conquest of adverse meteorological conditions. The most promising avenue to such mastery of the elements is through adaptations of radio. Intensive work extending over two years has resulted in the development and practical demonstration of a complete set of radio aids to flying on the civil airways of the United States. This development was carried on by the Bureau of Standards for the Aeronautics Branch of the Department of Commerce. The radio aids, which will now be installed on the principal airways, comprise a radio beacon system and telephone service from ground to aircraft. The required radio equipment on the airplanes is reduced to a short pole antenna and a simple receiving set weighing a few pounds, including a visual indicator which tells the pilot whether he is on the course or how far off. All of the expensive and powerful apparatus necessary for the system is on the ground, maintained by the Government. The radio beacons operate in the frequency band 285 to 315 kc and the telephone stations in the band 315 to 350 kc. These are allocated to air service by the 1927 International Radio Convention. For the present the beacons are adjusted to the frequency of 290 kc and the telephone stations to 333 kc. The directive radio beacon is a special kind of radio station, usually located at an airport, just off the landing field.
Exciton–polaritons in van der Waals heterostructures embedded in tunable microcavities (2015)

Layered materials can be assembled vertically to fabricate a new class of van der Waals heterostructures a few atomic layers thick, compatible with a wide range of substrates and optoelectronic device geometries, enabling new strategies for control of light-matter coupling. Here, we incorporate molybdenum diselenide/hexagonal boron nitride (MoSe2/hBN) quantum wells in a tunable optical microcavity. Part-light-part-matter polariton eigenstates are observed as a result of the strong coupling between MoSe2 excitons and cavity photons, evidenced from a clear anticrossing between the neutral exciton and the cavity modes with a splitting of 20 meV for a single MoSe2 monolayer, enhanced to 29 meV in MoSe2/hBN/MoSe2 double-quantum wells. The splitting at resonance provides an estimate of the exciton radiative lifetime of 0.4 ps. Our results pave the way for room-temperature polaritonic devices based on multiple-quantum-well van der Waals heterostructures, where polariton condensation and electrical polariton injection through the incorporation of graphene contacts may be realized.
Anticancer Active Illudins: Recent Developments of a Potent Alkylating Compound Class (2011)

An overview of anticancer active spirocyclopropanes of the illudin class is provided. After a short introduction on the history and general chemistry of illudins M and S, new discoveries concerning their mode of action and metabolism are reported as well as new synthetic endeavors towards derivatives with improved selectivity for and efficacy against cancer cells. In addition, common and recently tapped biological sources and isolation procedures for known and new illudins are discussed. Pertinent literature is covered up to 2010.
20-nm signal bandwidth after 147-amplifier chain using long-period gain-equalizers (2002)

Summary form only given. Long-haul, large-capacity wavelength-division multiplexing (WDM) transmission systems require broad WDM signal bandwidth, which can be expanded with broadband erbium-doped fiber amplifiers (EDFAs), gain-equalizers (GEQs), and pre-emphasis of optical senders. Twenty-four WDM signals transmission over 2526 km with a 18.4-nm bandwidth and 16 WDM signals transmission over 6000 km with a 12-nm bandwidth have been reported. In this paper, we demonstrate a 20-nm WDM signal bandwidth after 147-amplifier chain (5958-km transmission) using high alumina co-doped EDFAs and long-period gain-equalizers (GEQs). The main GEQs have free-spectral-ranges (FSRs) of 48 nm, which are about two times as long as the wavelength difference between a 1558-nm EDFA gain peak and a 1536-nm EDFA gain valley.
The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice (2018)

The sequences used for analysis can be found in the MG-RAST database under the project name MYNEWGUT3.
The Influence of Immunity on Raw Milk— Associated Campylobacter Infection (1987)

After a retreat to an Oregon farm, 19 of 31 college students developed an acute gastrointestinal illness. Campylobacter jejuni infection was recognized in all the ill students and caused asymptomatic infections in three others. In total, 22 (88%) of 25 students who consumed raw milk for the first time became infected as compared with none of two who had not consumed raw milk. Among ten persons who chronically consumed raw milk, none was ill, a striking difference from the 76% attack rate among the 25 acutely exposed students. The quantity of raw milk consumed was directly related to the occurrence and severity of illness. Acutely infected students showed significant rises in C jejuni-specific immunoglobulins, whereas the low antibody levels seen in unexposed persons did not rise. In contrast, acute-phase serum samples from persons with chronic exposure to raw milk showed elevated antibody levels to C jejuni. These findings indicate that chronic raw milk consumption is associated with elevated levels of C jejuni-specific serum antibodies and with immunity to symptomatic infection.
Contacts between the growing peptide chain and the 23S RNA in the 50S ribosomal subunit (1994)

Peptides of defined length carrying a diazirine photo-affinity label attached either to the α-NH2 group of the N-terminal methionine residue, or to the £-NH2 group of an immediately adjacent lysine residue, were prepared in situ on Escherichia coli ribosomes in the presence of a synthetic mRNA analogue. Peptide growth was stopped simply by withholding the aminoacyl-tRNA cognate to an appropriate downstream codon. After photo-activation at 350 nm the sites of cross-linking to ribosomal RNA were determined by our standard procedures; the C-terminal amino acid of each peptide was labelled with tritium, in order to confirm whether the individual cross-linked complexes contained the expected ‘full-length’ peptide, as opposed to shorter products. The shortest peptides became cross-linked to sites within the ‘peptidyl transferase ring’ of the 23S RNA, namely to positions 2062, 2506, 2585 and 2609. However, already when the peptide was three or four residues long, a new crosslink was observed several hundred nucleotides away in another secondary structural domain; this site, at position 1781, lies within one of several RNA regions which have been implicated in other studies as being located close to the peptidyl transferase ring. Further application of this approach, combined with model-building studies, should enable the path of the nascent peptide through the large ribosomal subunit to be definitively mapped.
Finding clauses in unrestricted text by finitary and stochastic methods (1988)

The paper presents and compares two different methods of parsing, a regular expression method and a stochastic method, with respect to their success in identifying basic clauses in unrestricted English text. These methods of parsing were developed in order to be applied to the task of improving the detection of large prosodic units in the Bell Labs text-to-speech system, and were so applied experimentally. The paper also discusses the notion of basic clause that was defined as the parsing target. The result of a comparison of the error rates of the two parsing methods in the recognition of basic clauses showed that there was a 13% error rate for the regular expression method and a 6.5% error rate for the stochastic method.
Computer generated holography: an introduction (1987)

A group of papers in the 15 Oct. 1987 issue of Applied Optics describe some recent advances in the field of computer generated holograms, and delineate historical trends.
The Eifel Detection Algorithm for TCP (2003)

The Eifel detection algorithm allows a TCP sender to detect a posteriori whether it has entered loss recovery unnecessarily. It requires that the TCP Timestamps option defined in RFC 1323 be enabled for a connection. The Eifel detection algorithm makes use of the fact that the TCP Timestamps option eliminates the retransmission ambiguity in TCP. Based on the timestamp of the first acceptable ACK that arrives during loss recovery, it decides whether loss recovery was entered unnecessarily. The Eifel detection algorithm provides a basis for future TCP enhancements. This includes response algorithms to back out of loss recovery by restoring a TCP sender's congestion control state.
An Evaluation of a Noninvasive Cardiac Output Measurement Using Partial Carbon Dioxide Rebreathing in Children (2004)

Cardiac output (CO) is an important hemodynamic measure that helps to guide the therapy of critically ill patients. Invasive CO assessment in infants and children is often avoided because of the inherent risks. A noninvasive CO monitor that uses partial rebreathing has been recently developed to determine CO via the Fick principle for carbon dioxide. There have been no clinical studies confirming its accuracy in pediatric patients. This is a prospective observational study of 37 children <12 yr of age who underwent cardiac catheterization. Under general anesthesia via an endotracheal tube without a leak, we made multiple CO measurements using thermodilution and compared them with noninvasively determined CO measurements. Paired measurements were analyzed for bias, precision, and correlation via Bland-Altman plot and linear regression. Noninvasive measurements showed a linear correlation with thermodilution CO assessment with an r value of 0.83 (P < 0.03). Bland-Altman analysis yielded a bias of -0.27 L/min and a precision +/-1.49 L/min. Cardiac index measurements demonstrated a decreased r value of 0.67 (P = 0.15) and a bias of -0.18 L . min(-1) . m(-2) and precision of +/-2.13 L . min(-1) . m(-2). Differences between partial rebreathing measurements and thermodilution measurements were largest in children with a body surface area of </=0.6 m(2) ventilated with tidal volumes <300 mL. Based on these findings, noninvasive CO measurement using partial rebreathing may be clinically acceptable in children with >0.6 m(2) body surface area and >300 mL tidal volume.
Nucleotide sequences from the capsid and pre-protein regions of dengue viruses from VietNam (1997)

Conference Abstract| February 01 1997 Nucleotide sequences from the capsid and pre-protein regions of dengue viruses from VietNam Nguyen Ngoc HUYEN; Nguyen Ngoc HUYEN *MRIC Biochemistry Group, N.E. Wales Institute, Plas Coch, Wrexham, Wales, UK, LL11 2AW.+Blood Transfusion and Haematology Centre, 118, Hung Vuong, Q5, Ho Chi Minh City, VietNam. Search for other works by this author on: This Site PubMed Google Scholar Tran van BE; Tran van BE +Blood Transfusion and Haematology Centre, 118, Hung Vuong, Q5, Ho Chi Minh City, VietNam. Search for other works by this author on: This Site PubMed Google Scholar Glenn E. MORRIS Glenn E. MORRIS *MRIC Biochemistry Group, N.E. Wales Institute, Plas Coch, Wrexham, Wales, UK, LL11 2AW. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1997) 25 (1): 54S. https://doi.org/10.1042/bst025054s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation Nguyen Ngoc HUYEN, Tran van BE, Glenn E. MORRIS; Nucleotide sequences from the capsid and pre-protein regions of dengue viruses from VietNam. Biochem Soc Trans 1 February 1997; 25 (1): 54S. doi: https://doi.org/10.1042/bst025054s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1997 Biochemical Society1997 Article PDF first page preview Close Modal You do not currently have access to this content.
ZnO/poly(N-vinylcarbazole) coaxial nanocables for white-light emissions (2014)

A new type of light emitting nanorod that emits white light is reported.