gebhart/patrepeval huggingface dataset:
Telecommunication systems engineering (1973)

From the Publisher:
This classic graduate- and research-level texty by two leading experts in the field of telecommunications is essential reading for anyone workign today in space and satellite digital communicatiions and those seeking a wider background in statistical communication theory and its applications. Ideal for practicing engineers as well as graduate students in communication systems courses, the book clearly presents and develops theory that can be used in the design and planning of telecommunication systems operating with either small or large performance margins. The book includes in its coverage a theory for use in the design of one-way and two-way phase-coherent and communication systems; and analysis and comparison of carrier and suppressed carrier synchronization techniques; treatment of the band-pass limiter theory; unification of phase-coherent detection with perfect and noisy synchronization reference signals. Convolutional codes, symbol synchronization, and noncoherent detection of M-ary signals are among the otehr subjects addressed in this comprehensive study. Dr. Lindsey, who is with the Communication Sciences Institute at the University of Southern California, and Dr. Simon, who is with the Jet Propulsion Laboratory at the California Institute of Technology, include at the end of each chapter a comprehensive set of problems that demonstrate the application of the theory developed. Unabridged Dover (1991) republication of the edition published by Prentice-Hall, Inc., Englewood Cliffs, N.J., 1973.265 line illustrations. 3 photographs. References at chapter ends. Problems. Index. xviii + 574pp. 5 3/8 x 8 1/2. Paperbound.
Self-treatment of benign paroxysmal positional vertigo (2004)

The authors compared the efficacy of a self-applied modified Semont maneuver (MSM) with self-treatment with a modified Epley procedure (MEP) in 70 patients with posterior canal benign paroxysmal positional vertigo. The response rate after 1 week, defined as absence of positional vertigo and torsional/upbeating nystagmus on positional testing, was 95% in the MEP group (n = 37) vs 58% in the MSM group (n = 33; p < 0.001). Treatment failure was related to incorrect performance of the maneuver in the MSM group, whereas treatment-related side effects did not differ significantly between the groups.
Pelvic Disruption (1980)

A precise radiologic technique for assessing the forces producing pelvic disruption has been helpful in arriving at a logical classification of pelvic injury. The radiologic examination should include anteroposterior, inlet and outlet views, as well as tomograms and occasionally computed-assisted tomographic evaluation (CT scanning). On the basis of this radiologic assessment with some biomechanical studies, a classification of three major forces producing injury is suggested. The anteroposterior and lateral compression types, while vastly different, may both have stable and unstable subtypes associated with them. The vertical shear fracture is always unstable. An accurate history and physical examination in conjunction with the above radiologic principles will lead the surgeon to a precise determination of the fracture pattern. A knowledge of the forces necessary to produce this pattern is helpful in the management of the patient with this particular traumatic lesion.
Determination of glycated albumin by enzyme-linked boronate immunoassay (ELBIA) (1998)

Abstract A new affinity method for quantification of glycated albumin by an enzyme-linked boronate-immunoassay (ELBIA) has been established, based on the interaction between boronic acids and the cis-diols of glycated human serum albumin (HSA) trapped by anti-HSA antibody. To evaluate the ELBIA, we first examined the accuracy of the conventional boronate affinity chromatographic (BAC) method. In the BAC method, 8.1–18.9% of nonglycated albumin calibrator nonspecifically bound to the boronate affinity column, values that were regarded as the column blank. In the modified BAC method, therefore, we subtracted the column blank value from the measured glycated albumin value to obtain the true value. Because glycated albumin values measured by ELBIA were exactly the same as reported by the modified BAC method, we suggest that the ELBIA results reflect the real status of albumin glycation. We have also developed a fully automated ELBIA system, allowing multiple, rapid, and precise measurements of glycated albumin.
Optical design of a miniature semi-integrated tunable laser on a silicon optical bench (2008)

There is an increasing demand for tunable lasers in telecommunications networks for test equipment, optical components and other applications. In DWDM systems, multiple data streams propagate concurrently on a single mode fiber. DWDM networks are based on a DFB lasers operating at a wavelength defined by ITU wavelength grid. Statistical variations associated with the manufacture of DFB laser results in yield losses. Continuously tunable external lasers are developed to overcome the limitations of DFB lasers. Various laser tuning mechanisms are being explored to provide external cavity tunable lasers to provide a stable single mode output. The packaged tunable laser source (TLS) for DWDM network also need to include several optical elements for isolation and data modulation like collimator, focusing lens, fiber pigtail, a modulator and output fiber segment. In this publication, we propose a novel semi integrated miniature high frequency tunable laser design based on Silicon Optical Bench (SiOB) concept. One of the mirrors is a movable MEMS structure changing the optical path length. We propose micro optical design between laser diode and the MEMS mirror for efficient optical coupling and side mode suppression. We also present the compatibility between the optical coupling and MEMS actuation range. We present the coupling efficiency results over the tuning range. We also propose a method of monitoring the output power of the tunable laser using waveguide coupler structures which are integrated in the silicon wafer and method of packaging in a miniature package compatible to the industry standard form factor.
Soft micromanipulation device with multiple degrees of freedom consisting of high polymer gel actuators (1999)

Dexterity and softness of micromanipulators are important issues in assembly of fragile complex microstructures. This paper presents micromanipulator devices with 3 and 6 degrees of freedom intended for soft dextrous motion. The 3-DOF device moved 2 mm at the maximum with a response of 13 Hz. Experiments of microscopic teleoperation proved that the device was suitable for dynamic micromotion. The 6-DOF device could control 3 translations and 3 rotations independently. The practical frequency range was up to 3 Hz, the maximum displacement was 0.4 mm, and the maximum rotation angle was 2 deg.
New stereocontrolled synthesis of prostaglandins via prostaglandin A2 (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew stereocontrolled synthesis of prostaglandins via prostaglandin A2E. J. Corey and John. MannCite this: J. Am. Chem. Soc. 1973, 95, 20, 6832–6833Publication Date (Print):October 1, 1973Publication History Published online1 May 2002Published inissue 1 October 1973https://pubs.acs.org/doi/10.1021/ja00801a053https://doi.org/10.1021/ja00801a053research-articleACS PublicationsRequest reuse permissionsArticle Views832Altmetric-Citations75LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Detecting coarse-grain parallelism using an interprocedural parallelizing compiler (1995)

This paper presents an extensive empirical evaluation of an interprocedural parallelizing compiler, developed as part of the Stanford SUIF compiler system. The system incorporates a comprehensive and integrated collection of analyses, including privatization and reduction recognition for both array and scalar variables, and symbolic analysis of array subscripts. The interprocedural analysis framework is designed to provide analysis results nearly as precise as full inlining but without its associated costs. Experimentation with this system shows that it is capable of detecting coarser granularity of parallelism than previously possible. Specifically, it can parallelize loops that span numerous procedures and hundreds of lines of codes, frequently requiring modifications to array data structures such as privatization and reduction transformations. Measurements from several standard benchmark suites demonstrate that an integrated combination of interprocedural analyses can substantially advance the capability of automatic parallelization technology.
Quantitative evaluation of the chicken lysozyme epitope in the HyHEL‐10 fab complex: Free energies and kinetics (1998)

The hen (chicken) egg-white lysozyme (HEWL) epitope for the monoclonal antibody HyHEL-10 Fab (Fab-10) was investigated by alanine scan mutagenesis. The association rate constants (k(on)) for the HEWL Fab-10 complexes were obtained from the homogenous solution method described in the preceding paper (Taylor et al., 1998). A new method for determining the dissociation rate constant (k(off)) for the complex, by trapping nascent free antibody with an inactive HEWL mutant is described. The values of k(on) fall within a factor of 2 of the wild-type (WT) HEWL value (1.43+/-0.13 X 10(6)M(-1)s(-1)), while the increases in k(off)more nearly reflect the total change in free energies of the complex (deltadeltaG(D)). The dissociation constants (K(D)) were measured directly in those cases where satisfactory kinetic data could not be obtained. The Y20A, K96A, and K97A HEWL.Fab-10 complexes are destabilized by more than 4 kcal/mol compared to the WT complex. The R21A, L75A, and D101A antibody complexes are moderately destabilized (0.7 < deltadeltaG(D)< or = 1.0 kcal/mol). Additional mutations of the "hotspot" residues (Tyr20, Lys96, Lys97) were constructed to probe, more precisely, the nature of their contributions to complex formation. The results show that the entire hydrocarbon side chains of Tyr20 and Lys97, and only the epsilon-amino group of Lys96, contribute to the stability of the complex. The value of deltadeltaG(D) for the R21A mutant complex is a distinct outlier in the Arg21 replacement series demonstrating the importance of supplementing alanine scan mutagenesis with additional mutations.
Architectural synthesis of performance-driven multipliers with accumulator interleaving (1993)

Article Free Access Share on Architectural synthesis of performance-driven multipliers with accumulator interleaving Authors: Debabrata Ghosh View Profile , S. K. Nandy View Profile , P. Sadayappan View Profile , K. Parthasarathy View Profile Authors Info & Claims DAC '93: Proceedings of the 30th international Design Automation ConferenceJuly 1993 Pages 303–307https://doi.org/10.1145/157485.164902Online:01 July 1993Publication History 2citation206DownloadsMetricsTotal Citations2Total Downloads206Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Fluorescein Angiography (2011)

It has been 50 years since fluorescein angiography was developed as a clinical procedure by 2 medical students at Indiana University. The story of its discovery and the recognition of its value to ophthalmology involve a combination of insight and serendipity. Fluorescein had been in use clinically for more than half a century, but it took a pulmonary medicine laboratory to provide the stimulus for the development of flash and barrier filters that would make vascular photography practical. The first article was rejected by the ophthalmology literature, but several clinics heard about it and soon documented the enormous diagnostic value of the procedure.
Pricing network resources for adaptive applications (2006)

The Differentiated Services framework (DiffServ) has been proposed to provide multiple Quality of Service (QoS) classes over IP networks. A network supporting multiple classes of service also requires a differentiated pricing structure. In this work, we propose a pricing algorithm in a DiffServ environment based on the cost of providing different levels of services, and on long-term average user resource demand of a service class. We integrate the proposed service-dependent pricing scheme with a dynamic pricing and service negotiation environment by considering a dynamic and congestion-sensitive pricing component. Pricing network services dynamically based on the level of service, usage, and congestion allows a more competitive price to be offered, allows the network to be used more efficiently, and provides a natural and equitable incentive for applications to adapt their service requests according to network conditions. We also develop the demand behavior of adaptive users based on a physically reasonable user utility function. Simulation results show that a congestion-sensitive pricing policy coupled with user rate adaptation is able to control congestion and allows a service class to meet its performance assurances under large or bursty offered loads, even without explicit admission control. Users are able to maintain a stable expenditure, and allowing users to migrate between service classes in response to price increases further stabilizes the individual service prices. When admission control is enforced, congestion-sensitive pricing still provides an advantage in terms of a much lower connection blocking rate at high loads.
Rationalization of electricity operation by centralized electricity monitoring and control equipment (2002)

Centralized electricity monitoring and controlling equipment was developed. The authors outline this equipment's hardware and software, and describe the application of this system to large-scale facilities. This equipment is a workstation-based power plant controller and supervisor and uses an individual processing system with a multiple communications control unit and data processing units arranged under control of the CPU. The system can monitor/control 128 remote stations.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Negative regulation of signaling by a soluble form of toll‐like receptor 9 (2011)

Nucleic acid structures are highly conserved through evolution and when self nucleic acids are aberrantly detected by toll-like receptors (TLRs) they contribute to autoimmune disease. For this reason, multiple regulatory mechanisms exist to prevent immune responses to self nucleic acids. TLR9 is a nucleic acid-sensing TLR that is regulated at multiple levels including association with accessory proteins, intracellular localization and proteolytic processing. In the endolysosomal compartment TLR9 is proteolytically processed to an 80 kDa form (p80) and this processing is a prerequisite for activation. Here, we identified a soluble form of TLR9 (sTLR9) generated by a novel proteolytic event that cleaved TLR9 between amino acids 724-735. Similar to p80, sTLR9 was generated in endosomes. However, generation of sTLR9 was independent of the cysteine protease cathepsin B, active at acidic pH, but partially dependent on cathepsin S, a protease active at neutral pH. Most importantly, sTLR9 inhibited TLR9-dependent signaling. Altogether, these data support a model where an intrinsic proteolytic processing mechanism negatively regulates TLR9 signaling. A proper balance between the independent proteolytic events probabably contributes to regulation of TLR9-mediated innate immunity and prevention of autoimmune disease.
A high-gain DSI-ADPCM system (2005)

This paper describes DSI-ADPCM system in which a digital speech interpolation (DSI) system is combined with an adaptive differential PCM (ADPCM). The speech detector in DSI detects speech signals above -51 dBm with 32 ms hangover time, and attains 36 % reduction of average activity of a trunk in the international long distance lines. The adaptive bit assignment to the voiced and unvoiced sounds is adopted to cope with the freeze-out condition. These facts result in a DSI gain of 3. Furthermore, the 4 bit encoding is applied to DSI output at ADPCM with 6 kHz sampling attaining an ADPCM gain of 2.6. While the frequency of PCM speech signal with 8 kHz sampling is shifted 250 Hz down to lower range before the conversion of the sampling frequency from 8 kHz to 6 kHz is made to avoid quality degradation. Thus the total gain of 7 is expected when DSI and ADPCM are incorporated, and has already been demonstrated by computer simulation with satisfactorily high quality of speech.
Targeted Therapy for Advanced Colorectal Cancer — More Is Not Always Better (2009)

During the past few years, the outlook for patients with colorectal cancer has brightened considerably. Fluorouracil, an inhibitor of thymidylate synthase (and therefore DNA synthesis), was until recently the only effective systemic treatment for this disease. Fluorouracil is usually administered with leucovorin (i.e., folinic acid), which appears to stabilize the binding of the drug to thymidylate synthase. Since 1996, three new cytotoxic drugs — capecitabine (an oral fluoropyrimidine), irinotecan (a topoisomerase I inhibitor that blocks DNA repair), and oxaliplatin (an inhibitor of DNA replication and possibly a down-regulator of the expression of thymidylate synthase) — have been introduced into clinical . . .
Are osteoporotic fractures due to osteoporosis? Impacts of a frailty pandemic in an aging world. (1998)

Osteoporosis is a major risk factor for fractures in the elderly. Osteoporotic (hip, forearm, and vertebral) fractures today strike hard on Western populations, with a lifetime risk in women similar to the risk for cardiovascular disease. The risk of dying from hip fracture equals breast cancer mortality. Osteoporotic fractures are associated with pain, crippling and social dependency; annual costs in the United States are between $7 to $20 billion, and the contribution from hip fractures is above 60%. Of all hospital beds in Europe, 1 to 1.5% are occupied by osteoporotic patients, a figure expected to more than double during the next fifty years. Whereas vertebral fractures mainly seem to be caused by osteoporosis alone, hip fractures are heavily affected by an age-dependent contributory risk factor, frailty. Frailty might act as an involutionary phenomenon or as comorbidity, particularly neurological; it affects fracture risk along several causal paths, but the increasing frequency and severity of falls are essential. Results of attempts to prevent falls are discouragingly poor. Nevertheless, identification of risk possessors, particularly demented elderly living in institutions, is substantial for directing preventive and treatment programs, mainly acting on general health and on osteoporosis. Frailty of populations increases with longevity. Consequently, projections of fracture occurrence are too conservative. The annual hip fracture incidence in Asia in 2050 might pass 10 million, rather than the hitherto forecasted 3.2 million, thus shifting tomorrow's burden of age-related fractures from the wealthier to the poorer countries. There is an immediate call for vigorous global actions to reallocate resources, to reorganize health care, and to institute high-risk prevention programs.
Changes in pulmonary adenosine triphosphate-binding proteins detected by nucleotide photoaffinity labeling following treatment of mice with the tumor-modulatory agent butylated hydroxytoluene. (1986)

Protein kinases play a central role in the regulation of normal and neoplastic growth. A novel approach to evaluating this role is to apply the photoaffinity analogue of adenosine 5'-triphosphate (ATP), 8-azido[gamma-32P]adenosine 5'-triphosphate (8-N3-[gamma-32P]ATP), to extracts obtained from nondividing and dividing tissues in order to label high affinity ATP receptors, including protein kinases. A pattern of ATP-binding proteins was observed on autoradiograms prepared from lung extracts which were reproducible upon repeated experimentation and was identical among extracts prepared from several inbred strains. Seven specifically photolabeled proteins were detected with molecular weights of 120,000, 84,000, 53,000, 51,000, 43,000, 41,000, and 33,000. The pneumotoxicity that results from treating mice with butylated hydroxytoluene (BHT) is followed by a stimulation of lung cell proliferation as part of the regenerative repair phase. Increased photoincorporation of 8-N3-[gamma-32P]ATP into proteins with molecular weights of 41,000, 37,000 and 33,000 resulted from BHT treatment. The following correlations between increased photoincorporation and lung repair, as defined by an increased lung weight/body weight ratio, were observed: (a) these changes shared a similar BHT dose dependency; (b) both followed the same time course and were reversible; (c) both lung damage and enhanced photolabeling were abolished if the mice were pretreated with cedrene, an inducer of drug-detoxifying enzymes; (d) the effect of BHT on ATP-binding proteins was agent specific, since urethan treatment did not affect photoincorporation. These results demonstrate that the specific photolabeling of ATP receptors in tissue extracts is a sensitive indicator of a particular growth-related repair process.
Production of Ultrafiltered Skim Milk Retentate Powder. 2. Functional Properties (1993)

High protein skim milk retentate powders with modified functional properties were produced using UP and spray drying. Different heat treatments (6S"C for 30 min, 7S'C for 28 s, and 8S"C for 28 s) and pH adjustments (6.4, 6.7, and 7.0) were applied before spray drying. The pH adjustment affected gel waterholding capacity, acid gel strength, emulsifying capacity, and foaming capacity. Heat treatment also affected gel waterholding capacity, acid gel strength, and emulsifying capacity, but not foaming capacity. The interaction of heat treatment and pH adjustment affected gel water-holding capacity, acid gel strength, emulsifying capacity, and foaming capacity.
Planar Texture Improvement in Cholesteric Liquid Crystal Cells (2009)

We investigate the effect of thermal annealing (TA) on cholesteric cells. When a cell is heated to the cholesteric–isotropic transition temperature (Tci), the cholesteric phase coexists with the isotropic phase. The isotropic domains become oily streaks, but the cholesteric domains merge with each other as the cell naturally cools to room temperature. A repeated Tci TA processes that entails heating the cell to Tci followed by cooling to room temperature effectively suppresses oily streaks and expands planar texture domains. Through this method, a defect-free cholesteric cell is achieved after five repeated Tci TA processes.