gebhart/patrepeval huggingface dataset:
Equilibrium surface orientation of lamellae (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEquilibrium surface orientation of lamellaeG. T. Pickett, T. A. Witten, and S. R. NagelCite this: Macromolecules 1993, 26, 12, 3194–3199Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/ma00064a033https://doi.org/10.1021/ma00064a033research-articleACS PublicationsRequest reuse permissionsArticle Views602Altmetric-Citations102LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Very High‐Elevation Mont Blanc Glaciated Areas not Affected by the 20th Century Climate Change (2009)

This paper analyses the impact of climate change over the last 100 years on highelevation glaciated areas of the Mont Blanc range, comprising ice fields covering the top of the Mont Blanc (4808 m) and Do ˆme du Gou ˆter (4300 m) areas.Surface ablation is negligible for these high-elevation areas and the surface mass balance is mainly controlled by snow accumulation.At Do ˆme du Gou ˆter, ice fluxes have been calculated through two transversal sections by two independent methods in order to assess long-term surface accumulation.A comparison between these results and recent accumulation observations, together with the strong relationship between valley precipitation and snow accumulation, suggests that surface accumulation rates did not change significantly over the entire 20th century.Moreover, the small ice thickness changes, less than 3 m on the average, observed at Mont Blanc and Do ˆme du Gou ˆter between 1905 and 2005 clearly reveal that these high-elevation glaciated areas have not been significantly affected by climate change over the last 100 years.
Poly-silicon TFT AM-OLED on thin flexible metal substrates (2003)

Thin metal foils present an excellent alternative to polymers for the fabrication of large area, flexible displays. Their main advantage spurs from their ability to withstand higher temperatures during processing; microelectronic fabrication at elevated temperatures offers the ability to utilize a variety of crystallization processes for the active layer of devices and thermally grown gate dielectrics. This can lead to high performance (high mobility, low threshold voltage) low cost and highly reliable thin film transistors. In some cases, the conductive substrate can also be used to provide power to the active devices, thus reducing layout complexity. This paper discusses the first successful attempt to design and fabricate a variety of active matrix organic light emitting diode displays on thin, flexible stainless steel foils. Different pixel architectures, such as two- and four-transistor implementations, and addressing modes, such as voltage- or current-driven schemese are examined. This work clearly demonstrates the advantages associated with the fabrication of OLED displays on thin metal foils, which - through roll-to-roll processing - can potentially result in revolutionizing today's display processing, leading to a new generation of low cost, high performance versatile display systems.
Purification of wheat germ agglutinin using affinity flocculation with chitosan and a subsequent centrifugation or flotation step (1989)

Affinity purification is by tradition almost equivalent to affinity chromatography. In this report, a purification process is described in which the affinity interaction is performed in free solution. A precipitation step follows, thereby separating the affinity bound material from free. Chitosan is used as a natural polyligand rich in N-acetyl-D-glucosamine and is, because of its specificity, used in affinity precipitation of wheat germ agglutinin (WGA). The polyligand is soluble at pH below 6.5 and precipitates at higher values, thus coprecipitating associated WGA. A process was developed where the overall yield of WGA was 70% and the final product gave a single band on SDS-PAGE. The process was also run on a larger scale, where even affinity flotation was included in the study as an alternative way to harvest the precipitate. Scaling up the affinity precipitation was a very easy task.
A Biologically Inspired QoS Routing Algorithm for Mobile Ad Hoc Networks (2005)

This paper presents EARA-QoS, a improved version of swarm-intelligence inspired ad hoc routing algorithm EARA introduced in (Z. Liu et al., 2004). In this algorithm, we use the principle of swarm intelligence to evolutionally maintain routing information. The biological concept of stigmergy is used to reduce the amount of control traffic. A light-weight QoS scheme is proposed to provide service-classified traffic control. The simulation results show that this novel routing algorithm performs well in a variety of network conditions.
Binding and internalization of recombinant human erythropoietin in murine erythroid precursor cells (1987)

Erythropoietin (EPO) biosynthetically labelled with [35S]cysteine was produced from Chinese hamster ovary (CHO) cells containing amplified copies of human EPO cDNA. The glycosylated recombinant [35S]EPO, purified to virtual radiochemical homogeneity, was biologically active. We studied the interaction of this labeled recombinant EPO with erythroid precursor cells from mice made anemic with phenylhydrazine. The [35S]-labeled molecule bound to erythroid precursors in a time- and temperature-dependent manner. The binding was specific for EPO, and neither insulin, transferrin, epidermal growth factor, nor multiplication stimulating activity could compete for EPO binding sites. In the presence of 0.2% sodium azide, which blocks 80% to 90% of internalization, the recombinant molecule bound with an apparent Kd of 750 pmol/L and 100 to 200 binding sites per cell at 37 degrees C. Asialo-EPO was a more effective competitor than sialated EPO for the available binding sites. Thus, the enhanced biological specific activity of asialo-EPO could result from its enhanced binding affinity. We also studied recombinant human EPO labeled with 125I and found that it also bound to the erythroid cells in a saturable and specific manner. After 90 minutes of incubation at 37 degrees C, most of the bound [35S]EPO was internalized, whereas most of the [125I]EPO remained on the cell surface. The reduced internalization of the iodinated molecule could account for the previously reported functional deficit associated with iodination.
A 3.4-mW 54.24-Mbps burst-mode injection-locked CMOS FSK transmitter (2011)

A burst-mode frequency-shift keying (FSK) transmitter is presented using injection locking technique for wireless neural signal recording. An initial single current pulse is injected to the LC tank to start up the oscillator quickly and, more importantly, to set the phase of the free-running oscillation at known value. We prove that the free-running oscillation phase is linearly related to the logarithm of the initial current pulse magnitude. With the free-running oscillation phase fixed, a gated reference signal can be injected at the optimum timing to achieve fast settling and consequently realize the high-data-rate burst-mode FSK transmission. The duty cycle of the reference signal is controlled to be 33% to reduce the required reference signal power by 73% approximately. With burst-mode operation and direct modulation by changing the self-resonance frequency of the oscillator, low power consumption and high energy efficiency is achieved. The transmitter is implemented in a 0.18-μm CMOS technology. It achieves a maximum data rate of 54.24 Mbps while consuming 3.4 mW from a 1.8-V supply, resulting in the high energy efficiency of 62 pJ/bit.
State-dependent Conformations of the Translocation Pathway in the Tyrosine Transporter Tyt1, a Novel Neurotransmitter:Sodium Symporter from Fusobacterium nucleatum (2006)

The gene of a novel prokaryotic member (Tyt1) of the neurotransmitter:sodium symporter (NSS) family has been cloned from Fusobacterium nucleatum. In contrast to eukaryotic and some prokaryotic NSSs, which contain 12 transmembrane domains (TMs), Tyt1 contains only 11 TMs, a characteristic shared by approximately 70% of prokaryotic NSS homologues. Nonetheless upon heterologous expression in an engineered Escherichia coli host, Tyt1 catalyzes robust Na+-dependent, highly selective l-tyrosine transport. Genetic engineering of Tyt1 variants devoid of cysteines or with individually retained endogenous cysteines at positions 18 or 238, at the cytoplasmic ends of TM1 and TM6, respectively, preserved normal transport activity. Whereas cysteine-less Tyt1 was resistant to the inhibitory effect of sulfhydryl-alkylating reagents, N-ethylmaleimide inhibited transport by Tyt1 variants containing either one or both of the endogenous cysteines, and this inhibition was altered by the substrates sodium and tyrosine, consistent with substrate-induced dynamics in the transport pathway. Our findings support a binding model of Tyt1 function in which an ordered sequence of substrate-induced structural changes reflects distinct conformational states of the transporter. This work identifies Tyt1 as the first functional bacterial NSS member putatively consisting of only 11 TMs and shows that Tyt1 is a suitable model for the study of NSS dynamics with relevance to structure/function relationships of human NSSs, including the dopamine, norepinephrine, serotonin, and gamma-aminobutyric acid transporters.
Exogenous Ca<sup>2+</sup>‐ATPase isoform effects on Ca<sup>2+</sup> transients of embryonic chicken and neonatal rat cardiac myocytes (2000)

1. Sarco-endoplasmic reticulum Ca2+-ATPase from fast skeletal (SERCA1) or cardiac muscle (SERCA2a) was expressed in embryonic chicken and neonatal rat cardiac myocytes by adenovirus vectors, with c-myc tags on both constructs to compare expression and distinguish exogenous from endogenous SERCA2a in myocytes. 2. Expression of the two isoforms was similar (approximately 3-fold higher than endogenous SERCA). However, SERCA1 activity was 2-fold greater than SERCA2a activity, due to intrinsic differences in turnover rates. Activation of both exogenous SERCA isoforms by Ca2+ was displaced to slightly lower [Ca2+], suggesting that the overexpressed isoforms were independent of phospholamban. In fact, phospholamban and calsequestrin expression were unchanged. 3. Decay time constants of cytosolic Ca2+ transients from cells overexpressing SERCA1 were reduced by 30-40 % and half-widths by 10-15 % compared to controls. SERCA2a overexpression produced much less acceleration of transients in chick than in rat, and less acceleration than SERCA1 overexpression in either species. There was no significant change in resting [Ca2+], peak amplitudes, or in the amount of Ca2+ releasable by caffeine from overexpression of either SERCA isoform. However, the amplitudes of the transients increased with SERCA1 overexpression when pacing frequency limited refilling of the sarcoplasmic reticulum. 4. It is concluded that total SERCA transport velocity has a primary effect on the decay phase of transients. Transport velocity is affected by SERCA isoform turnover rate, temperature, and/or SERCA copy number.
Circumferential Resection Margin Involvement in Stage III Rectal Cancer Patients Treated with Curative Resection Followed by Chemoradiotherapy: A Surrogate Marker for Local Recurrence? (2012)

In this study, local recurrence rate did not differ according to CRM involvement status in stage III rectal cancer patients, although CRM involvement was shown to be an independent poor prognostic factor. Accordingly, validation of the results of this study by further large prospective randomized trials is warranted.
Molecular motions in solid isotopic silanes (1969)

This paper reports the results of measurements of some thermodynamic properties (heat capacities, vapour pressures, density, heats of fusion) of two silanes, SiH4 and SiHD3, over a wide temperature range above T= 2.8 K. Residual entropies (neglecting nuclear spins) have been computed to be –0.3 ± 0.3 cal mol–1 deg.–1 for SiH4 and 2.5 ± 0.3 cal mol–1 deg.–1 for SiHD3. These results together with published ones from other kinds of experiments are compared with the more extensive data that are available for the solid isotopic methanes. The similarities and differences are used for making deductions about molecular motions in the solid silanes.
Identification and Structural Characterization of Naturally-Occurring Broad-Spectrum Cyclic Antibiotics Isolated from <i>Paenibacillus</i> (2015)

The rise of antimicrobial resistance necessitates the discovery and/or production of novel antibiotics. Isolated strains of Paenibacillus alvei were previously shown to exhibit antimicrobial activity against a number of pathogens, such as E. coli, Salmonella, and methicillin-resistant Staphylococcus aureus (MRSA). The responsible antimicrobial compounds were isolated from these Paenibacillus strains and a combination of low and high resolution mass spectrometry with multiple-stage tandem mass spectrometry was used for identification. A group of closely related cyclic lipopeptides was identified, differing primarily by fatty acid chain length and one of two possible amino acid substitutions. Variation in the fatty acid length resulted in mass differences of 14 Da and yielded groups of related MS(n) spectra. Despite the inherent complexity of MS/MS spectra of cyclic compounds, straightforward analysis of these spectra was accomplished by determining differences in complementary product ion series between compounds that differ in molecular weight by 14 Da. The primary peptide sequence assignment was confirmed through genome mining; the combination of these analytical tools represents a workflow that can be used for the identification of complex antibiotics. The compounds also share amino acid sequence similarity to a previously identified broad-spectrum antibiotic isolated from Paenibacillus. The presence of such a wide distribution of related compounds produced by the same organism represents a novel class of broad-spectrum antibiotic compounds.
The ILLIAC IV Processing Element (1969)

This paper describes the design of the processing element (PE) of I IV, a parallel processing computer consisting of 256 PE's, each with an associated 2048 word memory. Each PE-memory combination with its data-dependent controls is a computer in itself, devoid of those controls common to all PE-memory combinations, such as instruction decoding, instruction look-ahead, etc.
Surface area and porosity of primary silicate minerals (2000)

Surface area is important in quantifying mineral-water reaction rates. Specific surface area (SSA) was measured to investigate controls on this parameter for several primary silicate minerals (PSM) used to estimate rates of weathering. The SSA measured by gas adsorption for a given particle size of relatively impurity-free, laboratory-ground samples generally increases in the order: quartz ≈ olivine ≈ albite < oligoclase ≈ bytownite < hornblende ≈ diopside. Reproducibility of BET SSA values range from ±70% (SSA < 1000 cm2/g) to ± 5% (SSA > 4000 cm2/g) and values measured with N2 were observed to be up to 50% larger than values measured with Kr. For laboratory-ground Amelia albite and San Carlos olivine, SSA can be calculated using log (SSA, cm2/g) = b + m log (d), where d = grain diameter (μm), b = 5.2 ± 0.2 and m = -1.0 ± 0.1. A similar equation was previously published for laboratory-ground quartz. Some other samples showed SSA higher than predicted by these equations. In some cases, high SSA is attributed to significant second phase particulate content, but for other laboratory-ground samples, high SSA increased with observed hysteresis in the adsorption-desorption isotherms. Such hysteresis is consistent with the presence of pores with diameters in the range 2 to 50 nm (mesopores). In particular, porosity that contributes to BET-measured SSA is inferred for examples of laboratory-ground diopside, hornblende, and all compositions of plagioclase except albite, plus naturally weathered quartz, plagioclase, and potassium feldspar. Previous workers documented similar porosity in laboratory-ground potassium feldspar.
High Picture Quality Technologies for an S-VHS Portable VCR (1989)

Because of their high picture quality and low cost, S-VHS videocassette recorders (VCRs) have become popular in the growing professional video community. This article considers several technological improvements for higher picture quality, the main design goal of a new portable VCR. These include advanced metal heads and cylinder-mounted preamplifiers to improve carrier-to-noise ratio and a digital signal processor, including a time base corrector and a chrominance noise reducer, to improve the clarity of the reproduced picture.
Good Policy or Judicial Abdication: When Courts Uphold Arbitral Awards Which Are in Excess of the Arbitrator's Jurisdiction - Hall v. Superior Court (1994)

Legislatures and the court system have advanced a strong policy to encourage individuals to arbitrate disputes and avoid the traditional judicial system. 2 In order to promote this policy, it is vital that arbitrators' awards be respected and upheld if at all possible. Consequently, the grounds for review of arbitration awards are limited.' One of the grounds available for vacating an arbitral decision arises when an arbitrator exceeds his or her jurisdiction by purporting to decide issues not submitted by the parties for arbitral determination. 4 This Note discusses the potential consequences to the overall policy goals of encouraging arbitration when reviewing courts fail to vacate arbitration awards which purport to decide issues outside of the arbitrator's jurisdiction.
Antiallergenic 8-azapurines. Structural characterization of 9-diethylcarbamoyl-2-(2-propoxyphenyl)-8-azahypoxanthine (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntiallergenic 8-azapurines. Structural characterization of 9-diethylcarbamoyl-2-(2-propoxyphenyl)-8-azahypoxanthineH. Eugene LeMay Jr. and Derek J. HodgsonCite this: J. Am. Chem. Soc. 1978, 100, 20, 6474–6478Publication Date (Print):September 1, 1978Publication History Published online1 May 2002Published inissue 1 September 1978https://pubs.acs.org/doi/10.1021/ja00488a035https://doi.org/10.1021/ja00488a035research-articleACS PublicationsRequest reuse permissionsArticle Views39Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Finding and using implicit structure in human-organized spatial layouts of information (1995)

Article Finding and using implicit structure in human-organized spatial layouts of information Share on Authors: Frank M. Shipman Department of Computer Science, Texas A&M University, College Station, TX Department of Computer Science, Texas A&M University, College Station, TXView Profile , Catherine C. Marshall Department of Computer Science, Texas A&M University, College Station, TX Department of Computer Science, Texas A&M University, College Station, TXView Profile , Thomas P. Moran Xerox Palo Alto Research Center, 3333 Coyote Hill Road, Palo Alto, CA Xerox Palo Alto Research Center, 3333 Coyote Hill Road, Palo Alto, CAView Profile Authors Info & Claims CHI '95: Proceedings of the SIGCHI Conference on Human Factors in Computing SystemsMay 1995 Pages 346–353https://doi.org/10.1145/223904.223949Online:01 May 1995Publication History 74citation1,612DownloadsMetricsTotal Citations74Total Downloads1,612Last 12 Months14Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Iterative Ray Tracing between Boreholes for Underground Image Reconstruction (1980)

A computerized method is described for calculating an image of the refractive index distribution in a plane bounded by two underground boreholes. The scanning geometry is assumed to be limited to probing from borehole to borehole, with rays at numerous depths and angles to effectively cover the cross section between holes. A geometrical optics model is assumed for the transmission data. We stress situations where significant bending of electromagnetic or seismic rays occurs. Image reconstruction involves an iterated sequence of numerical ray tracing and linear system inversion. A similar approach, discussed in the literature, sometimes fails to converge. We report here our refinements of this method, including use of a smoothness constraint.
Effects of a Combination of Traditional Chinese Botanicals (Immune+) on the Secretion of Interleukin-1 <i>β</i> and Interferon- <i>γ</i> by Peripheral Blood Mononuclear Cells (2001)

The use of herbal and other botanical products, including those used extensively in traditional Chinese medicine, has increased dramatically in the last decade. Yet, little scientific research exists concerning their efficacy and safety. We examined the effects of Immune+, a combination of five botanicals frequently used in traditional Chinese medicine, on the production of two cytokines. For this purpose, unstimulated or phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells from healthy volunteers were incubated with different concentrations of Immune+. The secretion of interleukin-1beta (IL-1beta) and interferon-gamma (IFN-gamma) was measured after 72 hours of incubation. At the highest concentration tested (100 micro g/ml), Immune+ significantly increased the secretion of IL-1beta. Importantly, PHA alone had no effect on IL-1beta production, and the combination of PHA with Immune+ resulted in the same increase in IL-1beta production as seen with the botanical extract alone. Immune+ did not have any detectable effect on either unstimulated or PHA-stimulated IFN-gamma synthesis. These in vitro data support the concept that Immune+ may enhance human immune responses.