gebhart/patrepeval huggingface dataset:
Bore reconstruction of tubular ducts from its acoustic input impedance curve (2004)

In order to get accurate bore information of tubular objects from acoustical input impedance measurements an optimization approach is proposed and investigated. A suitable waveguide model is reviewed and reconstruction results are presented. Sensitivity of input impedance magnitude to bore variation indicates, that axial accuracy can be improved, without increasing the sampling rate. Advantages of the method are its increased numerical stability, its tolerance to white noise on top of measured data, no requirement to measure phase, and the fact, that measured data need not to be contiguous in the frequency domain. Frequency bands, which are difficult to measure, can be omitted.
Randomized Comparison of Transurethral Electroresection and Holmium:YAG Laser Vaporization for Symptomatic Benign Prostatic Hyperplasia (1999)

Although taking slightly longer to accomplish, holmium:YAG laser vaporization of BPH provides early results very similar to those of TURP with a shorter catheterization time and no initial dysuria or pain.
Host γd T cells Exacerbate Experimental Acute Graft-Versus-Host Disease through Activation of Host Antigen Presenting Cells. (2004)

Abstract Large numbers of T cells bearing γd T cell receptors are present in graft-versus-host disease (GVHD) target tissues. We investigated the potential role of host γd T cells during acute GVHD in a well-characterized GVHD model following full intensity conditioning (11 Gy TBI). BM and spleen T cells from BALB/c (H2d) donors were transplanted into wild type (wt) B6, aß T cell deficient B6 (aß −/−) or γd T cell deficient B6 (γd −/−) hosts. γd −/− hosts demonstrated significantly better day 35 survival (85%) than wt (40%) or aß−/− hosts (18%) (P&lt;0.05). Reconstitution of γd −/− B6 hosts with B6 type γd T cells 24 hr prior to BMT restored lethal GVHD (50 % day 35 survival). In vivo, γd −/− B6 hosts demonstrated at least a five fold reduction in donor T cell expansion and cytokine production. In vitro, T cells proliferated less when co-cultured with allogeneic γd −/− dendritic cells (DCs) than with wt DCs (40,127 ± 1634 vs. 72,503 ± 1296, P&lt;0.05). BM-derived DCs cultured with γd T cells caused greater proliferation of allogeneic T cells than DCs cultured with aß T cells (15.1 ± 21 x 104 vs. 5.1 ± 1.2 x 104, P&lt;0.05). We next tested the effect of γd T cells on host DCs in vivo using a model system in which only the DCs injected prior to BMT expressed the alloantigen that stimulated the GVHD reaction. MHC Class II −/− B6 mice that had been depleted of γd T cells were given 11 Gy TBI and injected one day prior to BMT with B6 DCs that had been co-cultured either with γd T cells or with medium. On day 0 both groups of recipient mice were injected with BM plus splenic T cells from allogeneic bm12 donors. On day +5, CD4+ donor T cells expanded four times more in recipients of DCs co-cultured with γd T cells than in recipients of control DCs and serum levels of TNF-a were significantly higher (36.7 + 6.8 vs. 21.3 + 3.7 pg/ml, P&lt;0.05). Together these data demonstrate that γd T cells amplify the stimulatory function of host DCs and increase the severity of GVHD, suggesting that a new therapeutic target for the prevention of the major BMT toxicity.
Optical rotatory power of 90° twisted nematic liquid crystals (1984)

A technique was developed and used to measure the rotatory power of 90° twisted nematic liquid crystals in the visible and infrared spectral regions. Experimental results for two liquid crystal mixtures, BDH-E7 and ZLI-1132, are in very good agreement with theoretical calculations for a wide spectral range and for different liquid crystal thicknesses. A quantitative relationship between liquid crystal birefringence, wavelength, and cell thickness was derived for use in the design of IR liquid crystal light valves with high contrast ratios and minimum response times.
Insider cyber threat situational awareness framwork using dynamic Bayesian networks (2009)

Insider cyber threat is a serious problem in recent years. Many traditional methods such as intrusion detection system and prevention system can not effectively deal with insider attack problems because they lack of dynamic inference capability to acquire and understand cyber situational awareness. This paper presented a framework model based on DBN to capture the dynamic user behavior and establish and improve inference ability. This model has used transition relationship of DBN and HMM and its better performance inference algorithm to infer next activity. Those performances are verified and compared by the experiments in the end.
Achieving excellent electro-optic activity and thermal stability in poled polymers through an expeditious crosslinking process (2011)

A series of highly efficient and thermally stable electro-optic (EO) polymers have been developed by poling and crosslinking in situ the blend of high glass-transition temperature (Tg) anthracene-containing polymers and acrylate-functionalized dendritic nonlinear optical (NLO) chromophores. By molecular engineering of the shape, nonlinearity, Tg, and crosslinking moieties of the chromophores and polymers, the resultant materials showed significantly enhanced EO activities (r33 values as high as 126 pm V−1 at 1310 nm) and alignment stability (up to 200 °C). Poling efficiency of these EO polymers could be improved by 35–50% by using simplified lattice hardening and poling protocols. The combined good processability, large EO activities, and high temperature stability endow these materials as promising candidates for device exploration in the CMOS-based photonics.
e-Healthcare Security Solution Framework (2012)

We examine e-Healthcare security challenges in order to address the emerging needs of a national digital healthcare solution. New security concerns arise in transmitting and processing of electronic medical records, personal healthcare records, patient billing records, as well as public health alerts, across many parties with varying security, privacy and trust levels. Additional security requirements in e-Healthcare settings have to be formulated beyond traditional data networking services. Our results include an e-Healthcare security solution framework that enables multi-party participation, allows variable visibility into selective parts of data, and guarantees end-to-end security control.
Wide-wavelength-band (30 nm) 10-Gb/s operation of InP-based Mach-Zehnder modulator with constant driving voltage of 2 V/sub pp/ (2005)

Wide-wavelength-band operation of InP-based Mach-Zehnder modulators is investigated. From the measured dependences of the half-wavelength voltage on operating wavelength and applied-bias voltage, it is shown that wide-wavelength operation with a constant driving voltage can be realized by adjusting the bias voltage for each operating wavelength. Ten-gigabits/second clear eye openings are demonstrated over a 30-nm wavelength range with a constant driving voltage of 2 V/sub pp/.
초등교사의 사고양식이 창의적 교수행동에 영향을 미치는가?: 교사효능감과 교수몰입의 매개효과 (2011)

이 연구는 초등학교 교사들의 사고양식, 교수몰입, 교사효능감 창의적 교수행동 간의 관계를 분석하고 선행연구들을 기초로 각 연구변인들 간의 구조적인 관계를 살펴보았다. 이를 위해 초등학교 288명의 자료를 수집하였다. 연구결과 첫째, 창의적 교수행동 중 인지적 지원은 사법적, 입법적 및 자유주의적 사고양식, 교사효능감 중에서는 자기조절효능감과 교수몰입 중에서는 인지적 몰입과 상대적으로 높은 정적상관을 나타냈다. 또한 정의적 지원은 입법적, 사법적 사고양식, 교사효능감 중에서는 자신감, 교수몰입 중에서는 쟁의적 몰입과 비교적 높은 정적상관을 보였다. 둘째, 초등교사의 사고양식은 창의적, 교수행동에 직접적으로 영향을 미치는 동시에 교사효능감과 교수몰입을 매개로 창의적 교수행동에 간접적으로 영향을 미치고, 교사효능감은 창의적 교수행동에 직접적 그리고 교수몰입을 통해 간접적으로 영향을 미친 모형이 적합한 모형임을 확인하였다. 셋째, 창의적 교수행동에 대한 직접적인 효과는 사고양식과 교사효능감이 높았으며, 간접적인 효과는 사고양식이 높게 나타났다. 이와 더불어 창의적 교수행동에 대한 교사효능감과 교수몰입 등의 매개효과는 통계적으로 유의하게 나타났다. 이상의 결과들을 토대로 학습자들의 창의성을 증진시키기 위한 교사의 창의적 교수방법과 수업활동에 대해 논의하였다.
Translation Limits Synthesis of an Assembly-Initiating Coat Protein of Filamentous Phage IKe (1998)

Translation is shown to be downregulated sharply between genes V and VII of IKe, a filamentous bacteriophage classed with the Ff group (phages f1, M13, and fd) but having only 55% DNA sequence identity to it. Genes V and VII encode the following proteins which are used in very different amounts: pV, used to coat the large number of viral DNA molecules prior to assembly, and pVII, used to serve as a cap with pIX in 3 to 5 copies on the end of the phage particle that emerges first from Escherichia coli. The genes are immediately adjacent to each other and are represented in the same amounts on the Ff and IKe mRNAs. Ff gene VII has an initiation site that lacks detectable intrinsic activity yet through coupling is translated at a level 10-fold lower than that of upstream gene V. The experiments reported reveal that by contrast, the IKe gene VII initiation site had detectable activity but was coupled only marginally to upstream translation. The IKe gene V and VII initiation sites both showed higher activities than the Ff sites, but the drop in translation at the IKe V-VII junction was unexpectedly severe, approximately 75-fold. As a result, gene VII is translated at similarly low levels in IKe- and Ff-infected hosts, suggesting that selection to limit its expression has occurred.
Deep Learning of Graphs with Ngram Convolutional Neural Networks (2017)

Convolutional Neural Network (CNN) has gained attractions in image analytics and speech recognition in recent years. However, employing CNN for classification of graphs remains to be challenging. This paper presents the Ngram graph-block based convolutional neural network model for classification of graphs. Our Ngram deep learning framework consists of three novel components. First, we introduce the concept of n-gram block to transform each raw graph object into a sequence of n-gram blocks connected through overlapping regions. Second, we introduce a diagonal convolution step to extract local patterns and connectivity features hidden in these n-gram blocks by performing n-gram normalization. Finally, we develop deeper global patterns based on the local patterns and the ways that they respond to overlapping regions by building a n-gram deep learning model using convolutional neural network. We evaluate the effectiveness of our approach by comparing it with the existing state of art methods using five real graph repositories from bioinformatics and social networks domains. Our results show that the Ngram approach outperforms existing methods with high accuracy and comparable performance.
Artificial Pancreas Using Living Beta Cells: Effects on Glucose Homeostasis in Diabetic Rats (1977)

An artificial pancreas consisting of beta cells cultured on synthetic semipermeable hollow fibers was tested in rats with alloxan-induced diabetes. When implanted ex vivo as arteriovenous shunts in the circulatory system these devices lowered concentrations of plasma glucose from 533 to between 110 and 130 milligrams per 100 milliliters, increased concentrations of plasma insulin, and restored intravenous glucose tolerance tests essentially to normal.
PILOT PLANTS.Production of Malleable Zirconium (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPILOT PLANTS.Production of Malleable ZirconiumW. J. Kroll and W. W. StephensCite this: Ind. Eng. Chem. 1950, 42, 2, 395–398Publication Date (Print):February 1, 1950Publication History Published online1 May 2002Published inissue 1 February 1950https://pubs.acs.org/doi/10.1021/ie50482a046https://doi.org/10.1021/ie50482a046research-articleACS PublicationsRequest reuse permissionsArticle Views65Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Expression of melanocyte stimulating hormone receptors correlates with mammalian pigmentation, and can be modulated by interferons (1988)

The relationship between melanogenesis and the expression of melanocyte stimulating hormone (MSH) receptors on the surface of melanocytes was examined using sublines generated from the melanotic JB/MS melanoma. JB/MS cells were propagated in long term culture to allow for phenotypic drift in their characteristics of differentiation, and then were cloned; the cloned cells ranged from well differentiated and pigmented to undifferentiated and amelanotic. Spontaneous and MSH-induced melanogenesis in these different lines was measured and correlated with the number of MSH receptors expressed. After 6 months of in vitro culture, the ability of the cells to respond to MSH was significantly reduced, as were the number of MSH receptors expressed; the cells had reduced pigmentation and were relatively undifferentiated histologically. Subsequently, clonally-derived pigmented cells were found to have numbers of surface MSH receptors (approximately 60,000 per cell) and levels of melanogenic activity similar to the original JB/MS cell line. However, an amelanotic clone had an even more dramatically reduced level of pigmentation which correlated with a further decrease in the expression of MSH receptors (less than 1,000 per cell) and the production of a potent melanogenic inhibitor. We also examined the responses of these various sublines to alpha, beta, and gamma-interferons and found significant heterogeneity in their abilities to respond to these cytokines. This study clearly shows that there is a direct correlation between melanogenesis and the expression of MSH receptors on the surface of melanocytes, and that melanogenic inhibitors may be critically involved in the regulation of mammalian pigmentation.
Morphology, Mechanical and Thermal Properties of Thermoplastic Polyurethane Containing Reduced Graphene Oxide and Graphene Nanoplatelets (2018)

Polyurethane/graphene nanocomposites were synthesized using commercial thermoplastic polyurethane (TPU, Apilon 52DE55), and two types of graphene derivatives: graphene nanoplatelets (GNP) and reduced graphene oxide (RGO). Fourier Transformation Infrared Spectroscopy Fourier Transformation Infrared Spectroscopy (FTIR) spectroscopy, TEM, and SEM microscopy and XRD techniques were used to chemically and structurally characterize GNP and RGO nanofillers. The properties of the new TPU nanocomposite materials were studied using thermal analysis techniques (Dynamical Mechanical Analysis (DMA), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TG)) to describe the influence of graphene nanofillers on polyurethane matrix. Our investigation describes the comparison of two types of graphene derivatives, commercial one (GNP) and synthesized (RGO) on thermoplastic polyurethanes. These nanofillers provides opportunities to achieve compatibility with the TPU matrix. The property enhancements are attributed commonly to high aspect ratio of graphene nanoplatelets and filler-polymer interactions at the interface. The obtained nanocomposites exhibit higher thermal and mechanical properties due to the good dispersion of both nanofillers into TPU matrix. It was found that the addition of 2 wt % of the nanofiller could lead to a significant reinforcement effect on the TPU matrix. Also, with high content of nanofiller (GNP and RGO), the Payne effect was observed.
Bone Regeneration Using a Bone Morphogenetic Protein-2 Saturated Slow-Release Gelatin Hydrogel Sheet (2010)

Bone regeneration methods using bone inductive cytokines show promise, however, due to early diffusion and absorption of single applications of these cytokines, the bone inductive effects are limited. In this study, such a system was applied, using gelatin hydrogel as a carrier to slowly release (bone morphogenetic proteins) BMP-2 over a relatively long period in vivo. By coupling this slow-release system with a biodegradable copolymer, this composite was evaluated by grafting into bone defect sites of a canine orbital floor fracture model. Radio-iodinated BMP-2 incorporated into the gelatin hydrogel carrier and subcutaneously implanted into nude mice showed a similar slow release (approximately, 60% at 3 days and 80% at 14 days) as the radiolabeled hydrogel carrier alone. In contrast, greater than 90% of fluid-injected BMP-2 was lost in the injection site within the first 8 hours. Using a dog model of orbital floor fracture, a complex of BMP-2-saturated gelatin hydrogel and a polylactide-based biodegradable copolymer was implanted into the orbital bone defect. Bone structural analysis, using radiography, histologic examination, and microfocus CT, showed greatly enhanced new bone formation and defect healing at 5 weeks in comparison to implanted biodegradable copolymer directly saturated with the same amount of BMP-2 (no slow-release hydrogel carrier). A trabecular structure resembling that normal bone tissue was restored in the new bone tissue generated by the slow-release constructs. Thus study demonstrates the potential of slow-release BMP-2 for bone healing of difficult defects.
Synthesis and Biological Evaluation of <i>N</i>-(Anthracen-9-ylmethyl)triamines as Molecular Recognition Elements for the Polyamine Transporter (2003)

An efficient modular synthesis of N(1)-substituted triamines containing different tether lengths between nitrogen centers was developed. A series of N(1)-(9-anthracenylmethyl)triamines were evaluated for biological activity in L1210 (murine leukemia), alpha-difluoromethylornithine (DFMO)-treated L1210, Chinese hamster ovary (CHO), and CHO-MG cell lines. All triamines 8 had increased potency in DFMO-treated L1210 cells. The 4,4- and 5,4-triamine systems had the highest affinity for the polyamine transporter (PAT) with L1210 K(i) values of 1.8 and 1.7 microM, respectively. This trend was also reflected in the CHO studies. Surprisingly, the respective 4,4- and 5,4-triamine systems had 150-fold and 38-fold higher cytotoxicity in CHO cells containing active polyamine transporters. Initial microscopy studies revealed the rapid formation of vesicular structures within A375 melanoma cells treated with the N(1)-(9-anthracenylmethyl)homospermidine (4,4-triamine) conjugate. In summary, the 4,4- and 5,4-triamines were identified as selective vector motifs to ferry anthracene into cells via the PAT.
Syntheses and Redox Properties of Bis(hydroxoruthenium) Complexes with Quinone and Bipyridine Ligands. Water-Oxidation Catalysis (2000)

The novel bridging ligand 1,8-bis(2,2':6',2"-terpyridyl)anthracene (btpyan) is synthesized by three reactions from 1,8-diformylanthracene to connect two [Ru(L)(OH)]+ units (L = 3,6-di-tert-butyl-1,2-benzoquinone (3,6-tBu2qui) and 2,2'-bipyridine (bpy)). An addition of tBuOK (2.0 equiv) to a methanolic solution of [RuII2(OH)2(3,6-tBu2qui)2(btpyan)](SbF6)2 ([1](SbF6)2) results in the generation of [RuII2(O)2(3,6-tBu2sq)2(btpyan)]0 (3,6-tBu2sq = 3,6-di-tert-butyl-1,2-semiquinone) due to the reduction of quinone coupled with the dissociation of the hydroxo protons. The resultant complex [RuII2(O)2(3,6-tBu2sq)2(btpyan)]0 undergoes ligand-localized oxidation at E1/2 = +0.40 V (vs Ag/AgCl) to give [RuII2(O)2(3,6-tBu2qui)2(btpyan)]2+ in MeOH solution. Furthermore, metal-localized oxidation of [RuII2(O)2(3,6-tBu2qui)2(btpyan)]2+ at Ep = +1.2 V in CF3CH2OH/ether or water gives [RuIII2(O)2(3,6-tBu2qui)2(btpyan)]4+, which catalyzes water oxidation. Controlled-potential electrolysis of [1](SbF6)2 at +1.70 V in the presence of H2O in CF3CH2OH evolves dioxygen with a current efficiency of 91% (21 turnovers). The turnover number of O2 evolution increases to 33,500 when the electrolysis is conducted in water (pH 4.0) by using a [1](SbF6)2-modified ITO electrode. On the other hand, the analogous complex [RuII2(OH)2(bpy)2(btpyan)](SbF6)2 ([2](SbF6)2) shows neither dissociation of the hydroxo protons, even in the presence of a large excess of tBuOK, nor activity for the oxidation of H2O under similar conditions.
Nocturnal Asthma and Changes in Circulating Epinephrine, Histamine, and Cortisol (1980)

NOCTURNAL and early morning wheezing is very common in asthmatics, 13 but the mechanisms are far from clear. The clinical importance of this symptom is underlined by the fact that many sudden deaths from asthma and many episodes of ventilatory arrest occur in the early morning.4 , 5 Several mechanisms have been proposed to explain nocturnal wheezing. There is little evidence that allergic factors such as house-dust mites in bedding have a major role, 6 and the same pattern of airway obstruction is observed in patients with nonatopic (intrinsic) asthma.3 Neither the supine posture nor sleep patterns appear to be important, and sleeping itself . . .
Polymerized unsymmetrical iron post-metallocene catalyst for ethylene polymerization (2002)

The unsymmetrical allyl containing post-metallocene complex [ArN = C( Me)] [(ArN)-N-' = C(Me)]C5H3NFeCl2 [Ar = 2,6(i- Pr)(2)C6H3, Ar' = 4-allyl-2,6-(i-Pr)(2)C6H3] (3) has been prepared and characterized. Complex (3) can be co-polymerized with styrene in the presence of radical initiator to produce polymerized post-metallocene catalyst which exhibits high activity for ethylene polymerization (2.5 x 10(6) g PE/mol Fe.h).
A New Synthetic Method of Preparing Iodohydrin and Bromohydrin Derivatives through in situ Generation of Hypohalous Acids from H5IO6 and NaBrO3 in the Presence of NaHSO3 (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Synthetic Method of Preparing Iodohydrin and Bromohydrin Derivatives through in situ Generation of Hypohalous Acids from H5IO6 and NaBrO3 in the Presence of NaHSO3Haruyoshi Masuda, Kiyoshi Takase, Masahiro Nishio, Akira Hasegawa, Yutaka Nishiyama, and Yasutaka IshiiCite this: J. Org. Chem. 1994, 59, 19, 5550–5555Publication Date (Print):September 1, 1994Publication History Published online1 May 2002Published inissue 1 September 1994https://pubs.acs.org/doi/10.1021/jo00098a012https://doi.org/10.1021/jo00098a012research-articleACS PublicationsRequest reuse permissionsArticle Views1556Altmetric-Citations98LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts