gebhart/patrepeval huggingface dataset:
Developing a simulator application to test the billing platform in telecom industry (2013)

Billing Mediation Platform (BMP) in telecommunication industry is used to process real-time streams of Call Detail Records (CDRs) which can be a massive number a day. The generated records by BMP can be deployed for billing purposes, fraud detection, spam filtering, traffic analysis, and churn forecast. Several of these applications are distinguished by real-time processing requiring low-latency analysis of CDRs. Testing of such a platform carries diverse aspects like stress testing of analytics for scalability and what-if scenarios which require generating of CDRs with realistic volumetric and appropriate properties. The approach of this project is to build user friendly and flexible application which assists the development department to test their billing solution occasionally. These generators projects have been around for a while the only difference are the potions they cover and the purpose they will be used for. This paper proposes to use a simulator application to test the BMPs with simulating CDRs. The Simulated CDRs are modifiable based on the user requirements and represent real world data.
Translating XSLT programs to Efficient SQL queries (2002)

We present an algorithm for translating XSLT programs into SQL. Our context is that of virtual XML publishing, in which a single XML view is defined from a relational database, and subsequently queried with XSLT programs. Each XSLT program is translated into a single SQL query and run entirely in the database engine. Our translation works for a large fragment of XSLT, which we define, that includes descendant/ancestor axis, recursive templates, modes, parameters, and aggregates. We put considerable effort in generating correct and efficient SQL queries and describe several optimization techniques to achieve this efficiency. We have tested our system on all 22 SQL queries of the TPC-H database benchmark which we represented in XSLT and then translated back to SQL using our translator.
Multi-User Interference Cancellation Scheme(s) for Muliple Carrier Frequency Offset Compensation in Uplink OFDMA (2006)

We consider the uplink of an orthogonal frequency division multiple access (OFDMA)-based system, where each mobile station (MS) experiences a different carrier frequency offset (CFO). Unconnected CFOs destroy the orthogonality among subcarriers, which could cause severe inter-carrier interference (ICI) and degrade the system performance considerably. In this paper, we propose a novel multi-user interference (MUI) cancellation scheme for uplink OFDMA, which utilizes multiple orthogonal frequency division multiplexing (OFDM)-demodulators architecture to correct and then compensate the negative effects of multiple CFOs at the receiver's side. Numerical evaluation has shown a considerable performance gain compared to the conventional receiver
The AML1/ETO fusion protein activates transcription of BCL-2 (1996)

The AML1 gene, located on chromosome 21, is involved in several distinct chromosomal translocations in human leukemia. In t(8;21) acute myelogenous leukemia (AML), the AML1 gene is juxtaposed to the ETO gene located on chromosome 8, generating an AML1/ETO fusion protein. Both AML1/ETO and the AML1 proteins recognize the same consensus DNA-binding motif (TGT/CGGT), which is found in the promoters of several genes involved in hematopoiesis. We found that two myeloid leukemia cell lines with the t(8;21) translocation, Kasumi and SKNO-1, have elevated levels of BCL-2 protein compared with other myeloid cell lines. In addition, we identified a consensus AML1 binding site in the BCL-2 promoter. Thus far, AML1/ETO has been shown to dominantly repress its target genes; however, we found that AML1/ETO activates transcription of the BCL-2 gene in U937 cells. This activation requires the presence of both the runt homology domain (rhd) and the C-terminal portion of AML1/ETO. We demonstrated sequence specific binding of both AML1A and AML1/ETO to the TGTGGT sequence in the BCL-2 promoter and showed that the AML1 binding site is required for responsiveness to AML1/ETO. Interestingly, AML1A and AML1B do not modulate the activity of the BCL-2 promoter. The elevated levels of BCL-2 in cells that express AML1/ETO may prolong their life span and contribute to the development of t(8;21) leukemia.
Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung (2011)

VEGFB and PlGF can either inhibit or potentiate the actions of VEGFA, depending on their relative concentrations, which change in the hypoxic lung. Thus their actions in vivo depend on their specific concentrations within the microenvironment of the alveolar wall during the course of adaptation to pulmonary hypoxia.
Does light pose a hazard to the macula in aphakia? (1985)

The changes produced within the retina by ultraviolet and blue-violet light are discussed in relation to the increased sensitivity of aphakic and pseudophakic eyes to actinic damage.
Optimal b Values for Generation of Computed High-b-Value DW Images (2016)

Optimal b values should be considered when acquiring images for the derivation of computed DW images.
Bagging for path-based clustering (2003)

A resampling scheme for clustering with similarity to bootstrap aggregation (bagging) is presented. Bagging is used to improve the quality of path-based clustering, a data clustering method that can extract elongated structures from data in a noise robust way. The results of an agglomerative optimization method are influenced by small fluctuations of the input data. To increase the reliability of clustering solutions, a stochastic resampling method is developed to infer consensus clusters. A related reliability measure allows us to estimate the number of clusters, based on the stability of an optimized cluster solution under resampling. The quality of path-based clustering with resampling is evaluated on a large image data set of human segmentations.
Acute Kidney Injury Biomarkers - Needs, Present Status, and Future Promise. (2006)

In the last decade, great progress has been made in dissecting the molecular mechanisms of Acute Kidney Injury (AKI; Also known as Acute Renal Failure, ARF)); however, translation of these findings to therapeutics of clinical utility has lagged. Development of therapeutics for AKI is has been slow and garnered limited industry interest because AKI is poorly characterized and difficult to diagnose early. Additional challenges include an inability to predict severity, measure progression, or response to therapy, all of which add complexity and risk to clinical trials. A standard definition of AKI is being developed, which will facilitate progress greatly. However, the over-reliance on serum creatinine as a marker of renal function and injury and the absence of additional disease markers has hampered clinical trials for AKI. Serum creatinine in AKI has poor sensitivity and specificity; patients are not in steady state, hence serum creatinine lags behind both renal injury and renal recovery. Conventional urine markers (casts, fractional excretion of sodium) are non-specific and insensitive. Reliance on traditional markers slows recognition of AKI and hence delays nephrologic consultation and discontinuation of nephrotoxic agents, and complicates drug development.
SUBCELLUAR SITES FOR SYNTHESIS OF CHONDROMUCOPROTEIN OF CARTILAGE (1968)

Microsomes from embryonic cartilage have been subfractionated to yield smooth microsomes and rough microsomes. The in vitro enzymic activities involved in chondroitin sulfate biosynthesis have been assayed in these subfractions. The results demonstrate that all of the activities necessary for linkage to protein as well as for completion of the polysaccharide chain are present in both the rough and smooth fractions. Only in the case of the polymerization of N-acetylgalactosamine and glucuronic acid could enzyme assays be done independent of endogenous acceptor. This enzyme(s) was equally distributed between the rough and smooth fractions. The activities for the addition of xylose and galactose to protein were highest in the rough fraction while that for sulfation was highest in the smooth fraction. These findings suggest that polysaccharide chain-initiation occurs in the rough endoplasmic reticulum and that chain completion occurs in the smooth reticulum. This pattern is consistent with modern theories of synthesis, transfer, and export of extracellular macromolecules.
Cytotoxicity of Algae Extracts on Normal and Malignant Cells (2011)

Algae preparations are commonly used in alternative medicine. We examined the effects of algae extracts on normal hematopoietic cells and leukemia cells. Ethanol extracts were prepared of Dunaliella salina (Dun), Astaxanthin (Ast), Spirulina platensis (Spir), and Aphanizomenon flos-aquae (AFA). Cell viability effects were completed by Annexin staining. Ast and AFA inhibited HL-60 and MV-4-11 whereas Dun and Spir had no effect. Primary AML blasts demonstrated increased apoptosis in AFA. Primary CLL cells showed apoptosis at 24 hours after exposure to Dun, Ast, Spir, and AFA. High AFA concentrations decreased viability of normal marrow cells. Normal CD34+ viability was inhibited by Dun. Dun and AFA inhibited BFU-E, but all extracts inhibited CFU-GM. Cell-cycle analysis of AML cell lines showed G0/G1 arrest in the presence of AFA. These data suggest that algae extracts may inhibit AML cell lines and leukemia blasts, but they may also have potential inhibitory effects on normal hematopoiesis.
The role of confocal microscopy in the dermato-oncology practice. (2011)

Reflectance-mode confocal microscopy (RCM) is a new in vivo skin imaging technique. We present our one-year experience in RCM examinations in skin tumors and the retrospective analysis of patients enrolled in the Dermatological Department of 'N. Paulescu' Institute using the Fotofinder Dermoscope IIŴ for the dermatoscopy analysis and VivaScope 1500Ŵ for in vivo RCM. We established the rank of RCM in the complex algorithm of skin cancer diagnose, showing that the presented experience can open new possibilities to implement this automated image analyzing system in the routine practice. Our analyzed cases clearly showed that confocal microscopy, therefore, optical biopsy, could guide the clinician towards an accurate diagnosis before surgical removal. Moreover, we emphasized that the development of this technique increases the potential of future teledermatologic applications.
Second primary tumors in patients with hereditary retinoblastoma: A register-based follow-up study, 1945–1994 (1996)

The aim of this register-based follow-up study was to evaluate the long-term cumulative incidence of second primary tumors (SPT) among survivors of hereditary retinoblastoma, with special interest for the incidence of pineoblastoma in retinoblastoma patients born after 1970. The Dutch Retinoblastoma Register was completed and updated: in the period 1945-1994, 639 retinoblastoma patients were registered. The vital status of each patient was obtained from the municipal registries and the Central Office of Genealogy. SPT were traced and histopathologically confirmed. Survival curves and cumulative incidence of SPT were calculated by the Kaplan-Meier method. The survival of patients with hereditary retinoblastoma was significantly shorter than that of patients with non-hereditary retinoblastoma. The cumulative incidence of SPT in hereditary patients was 3.7 and 17.7% at the ages of 10 and 35 years, respectively. Long-term follow-up revealed a high proportion of melanomas (7 melanomas out of 28 SPT). In the sub-cohort of the hereditary-retinoblastoma patient group born after 1970, the cumulative incidence of pineoblastomas at the age of 5 years was 9.3%. Our results suggest that patients with hereditary retinoblastoma should have careful follow-up, and procedures for diagnosing SPT and pineoblastomas at an early and potentially treatable stage should be developed.
Design and Performance of a Test Facility for Evaluating Potato Sprout Inhibitors (1994)

We developed a 216-container system and performed replicated experiments evaluating 3 concentrations of 10 compounds, plus a control and a reference, applied via three methods in two walk-in environmental chambers. The reference, isopropyl (N-3-chlorophenol)carbamate (CIPC) maintained over 50% nonsprouting tubers and all untreated controls sprouted early. None of the 10 test compounds appeared to be as effective as the CIPC reference in any of the concentrations. There were no important differences in sprouting associated with location in the test rooms. These results verify the appropriateness of our system design and simplify future experimental design considerations.
Hammerhead Ribozyme Mechanism:  A Ribonucleotide 5‘ to the Substrate Cleavage Site Is Not Essential (2000)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionHammerhead Ribozyme Mechanism: A Ribonucleotide 5' to the Substrate Cleavage Site Is Not EssentialAnilkumar R. Kore and Fritz EcksteinCite this: Biochemistry 2000, 39, 3, 624Publication Date (Web):January 18, 2000Publication History Published online18 January 2000Published inissue 1 January 2000https://pubs.acs.org/doi/10.1021/bi995098chttps://doi.org/10.1021/bi995098ccorrectionACS PublicationsCopyright © 2000 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views277Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (5 KB) Get e-Alertsclose Get e-Alerts
The Anticipatory Control of a Cyclically Permutable Memory (1973)

A control method based on anticipatory shift with lookahead is proposed for accessing files stored in a cyclically permutable memory as characterized by, for example, bubble-domain devices. The performance of this method is analyzed and is shown to yield significant reduction of access time. By using a basic simple model, an explicit formula is obtained for relating performance to the size of requests, the shift register length, and the number of control sections allowed. Several generalizations are also discussed.
Screening of Bacterial Cellulose-producing<i>Acetobacter</i>Strains Suitable for Agitated Culture (1995)

Journal Article Screening of Bacterial Cellulose-producing Acetobacter Strains Suitable for Agitated Culture Get access Hiroshi Toyosaki, Hiroshi Toyosaki Bio-Polymer Research Co., Ltd., KSP R&D Business-park Bldg. B-1015, 3–2–1, Sakato, Takatsu-ku, Kawasaki-shi 213, Japan Search for other works by this author on: Oxford Academic Google Scholar Takaaki Naritomi, Takaaki Naritomi Bio-Polymer Research Co., Ltd., KSP R&D Business-park Bldg. B-1015, 3–2–1, Sakato, Takatsu-ku, Kawasaki-shi 213, Japan Search for other works by this author on: Oxford Academic Google Scholar Akira Seto, Akira Seto Bio-Polymer Research Co., Ltd., KSP R&D Business-park Bldg. B-1015, 3–2–1, Sakato, Takatsu-ku, Kawasaki-shi 213, Japan Search for other works by this author on: Oxford Academic Google Scholar Masanobu Matsuoka, Masanobu Matsuoka Bio-Polymer Research Co., Ltd., KSP R&D Business-park Bldg. B-1015, 3–2–1, Sakato, Takatsu-ku, Kawasaki-shi 213, Japan Search for other works by this author on: Oxford Academic Google Scholar Takayasu Tsuchida, Takayasu Tsuchida Bio-Polymer Research Co., Ltd., KSP R&D Business-park Bldg. B-1015, 3–2–1, Sakato, Takatsu-ku, Kawasaki-shi 213, Japan Corresponding author. Search for other works by this author on: Oxford Academic Google Scholar Fumihiro Yoshinaga Fumihiro Yoshinaga Bio-Polymer Research Co., Ltd., KSP R&D Business-park Bldg. B-1015, 3–2–1, Sakato, Takatsu-ku, Kawasaki-shi 213, Japan Search for other works by this author on: Oxford Academic Google Scholar Bioscience, Biotechnology, and Biochemistry, Volume 59, Issue 8, 1 January 1995, Pages 1498–1502, https://doi.org/10.1271/bbb.59.1498 Published: 01 January 1995 Article history Published: 01 January 1995 Received: 06 February 1995
Serum glucose: effects on tumor and normal tissue accumulation of 2-[F-18]-fluoro-2-deoxy-D-glucose in rodents with mammary carcinoma. (1992)

The positron-emitter-labeled glucose analogue 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) accumulates into many cancers after intravenous injection, but the effect of serum glucose levels on FDG uptake in the tumor has not been extensively studied. In vitro, elevated media glucose levels markedly diminished FDG and FDG 6-phosphate uptake and retention in human adenocarcinoma cells, while insulin had no effect. Mammary cancers were established subcutaneously in 12 rats. Six control rats with mammary tumors were fasted overnight. Hyperglycemia was established in six rats by means of continuous glucose infusion (glucose clamp). All animals were then intravenously administered 50 microCi of FDG. Serum glucose levels were 87 mg/dL (4.83 mmol/L) in the control animals and more than 900 mg/dL (49.9 mmol/L) in the hyperglycemic animals. One hour after injection of FDG, mean F-18 uptake in the tumor, brain, small bowel, and ovaries was 2.7-9.7 times lower in the hyperglycemic animals (P less than .02). Mean F-18 activity in the kidneys tended to be somewhat higher in the hyperglycemic animals. FDG uptake in other tissues was comparable between the control and hyperglycemic groups. These data suggest that high serum glucose levels may substantially impair visceral tumor imaging with FDG positron emission tomography.
Purification and Partial Characterization of a Fructanase which Hydrolyzes Natural Polysaccharides from Sugarcane Juice (1990)

A new sugarcane (Saccharum officinarum L.) fructanase which hydrolyzes both high molecular weight polysaccharides mid R:Fructose(4):Galactitol(5)mid R:(n) (SP) and moderate-sized carbohydrates mid R:Fructose(2):Galactitol(3)3mid R:(n) (MMWC) has been purified from sugarcane juice. The K(m) value has been estimated to be 33.7 micrograms per milliliter and 20 micrograms per milliliter for SP and MMWC, respectively. The optimal pH and temperature values are 6.0 and 30 degrees C, respectively. Purified protein has a pl value of 6.35 and a molecular weight of 13.2 kilodaltons. Fructanase activity appears to be Mn(2+)-dependent.
CovertBand (2017)

This paper contributes a novel method for low-cost, covert physical sensing and, by doing so, surfaces new privacy threats. We demonstrate how a smartphone and portable speaker playing music with embedded, inaudible signals can track multiple individuals’ locations and activities both within a room and through barriers in 2D space. We achieve this by transforming a smartphone into an active sonar system that emits a combination of a sonar pulse and music and listens to the reflections off of humans in the environment. Our implementation, CovertBand, monitors minute changes to these reflections to track multiple people concurrently and to recognize different types of motion, leaking information about where people are in addition to what they may be doing. We evaluated CovertBand by running experiments in five homes in the Seattle area, showing that we can localize both single and multiple individuals through barriers. These tests show CovertBand can track walking subjects with a mean tracking error of 18 cm and subjects moving at a fixed position with an accuracy of 8 cm at up to 6 m in line-of-sight and 3 m through barriers. We test a variety of rhythmic motions such as pumping arms, jumping, and supine pelvic tilts in through-wall scenarios and show that they produce discernibly different spectrograms from walking in the acoustic reflections. In tests with 33 subjects, we also show that even in ideal scenarios, listeners were unlikely to detect a CovertBand attack.
RF MEMS reliability (2004)

Device reliability is a key factor in the ultimate insertion of RF MEMS devices into operational systems. In particular, cycle lifetimes of contacting devices such as RF switches can be technically challenging due to the requirement of good contact electrical performance under operational stresses. This paper presents a general discussion of the reliability limiting mechanisms that can impact RF MEMS devices, with an emphasis on the issues relevant to RF switch cycling lifetimes.
Brain Amyloid and Alzheimer Disease (1988)

Clinicopathologic features of Alzheimer disease, the commonest cause of presenile or senile dementia, are presented. Several of the microscopic brain lesions found in patients with this dementia share the staining properties of amyloid and at least two of these lesions (senile plaque cores and amyloid angiopathy) are biochemically identical. Theories pertinent to the origins of brain amyloid and its role in the pathogenesis of Alzheimer disease are discussed in relation to theories of the cause of this dementia. Possible treatments for Alzheimer disease developed from our knowledge of brain amyloid processing and biochemistry are considered.
Micro/miniature shape memory alloy actuator (2002)

Shape memory alloy (SMA) has great potential for microminiature actuators. The feasibility is discussed, and theoretical estimates based on scale effect are presented. Control schemes for microminiature SMA servoactuators are discussed, and a control scheme is proposed. Combined with electric resistance feedback and position feedback, it enables the author to control stiffness of SMA directly and to sense force without a force sensor. Experimental verifications are reported. The application of a miniature SMA actuator to a miniature clean gripper with position-force hybrid control for microelectronics manufacture is presented. Fabrication of a thin film micro SMA actuator is investigated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Hepatic fibrosis and cirrhosis in the Fontan circulation: a detailed morphological study (2007)

The histological features of the liver in patients with a Fontan circulation are similar to those described in cardiac sclerosis. Sinusoidal dilatation and sinusoidal fibrosis are marked in the Fontan series. The presence of a significant amount of orcein negative sinusoidal fibrosis suggests there may be a remediable component, although the dense fibrous bands are predominantly orcein positive, suggesting chronicity and permanence. No inflammation or hepatocellular damage is evident, suggesting that fibrosis may be mediated by a non-inflammatory mechanism.