gebhart/patrepeval huggingface dataset:
Novel, Solvent-Free, Single Ion Conductive Polymer Electrolytes (2008)

This project report concerns studies on the synthesis of new polymer electrolytes for application in lithium and lithium-ion batteries characterized by limited participation of anions in the transport of electrical charge. Studies were carried out additive organoboron compounds and on composite electrolytes with supramolecular anion receptors.
Ultrasonic gas analyser for high resolution determination of binary-gas composition (1986)

The composition of isothermal binary-gas mixtures can be determined by measuring the velocity of sound in the gas. A 40 kHz oscillator is used to generate a sine-wave signal which travels through a tube filled with the gas and activates a piezoelectric crystal positioned at the other end of the tube. The phase shift between the electrical voltages of transmitter and receiver varies with the velocity of sound and thus with the composition of the gas. An electronic circuit provides an output signal proportional to the phase shift. The device has been applied to analyse mixtures of propane and ethene. The acoustic gas analyser described may be used to determine concentration changes in the gas mixtures used down to 0.008% by volume.
Reactivity Studies and Cast Elastomers Based on <i>trans</i>-Cyclohexane-1,4-Diisocyanate and 1,4-Phenylene Diisocyanates (1981)

p-Phenylene diisocyanate (PPDI) and trans-cyclohexane-1,4-diisocyanate (CHDI), produced by the Hofmann degradation of the corresponding acid amides (1) have become available in developmental quantities for polyurethane production (2). Due to the symmetrical structure of both these molecules and their rigid, rod-like molecular shape, a very orderly structure in the build-up of the hard segments will be promoted in the polyurethane system. These structural features could enable the resulting elastomers to perform better under high and low temperature conditions and to achieve high modulus. Previous kinetic studies (3-7) showed that PPDI had a high reactivity, but no kinetic data were available for the reactivity of CHDI. Three model isocyanate reactions catalyzed with both tertiary amine and organotin catalysts were carried out with PPDI or CHDI and n-butanol (urethane formation) and water (urea formation) as well as cyclotrimerization (isocyanurate formation) in suitable solvents (toluene, cellosolve acetate and butyl acetate). Four widely used commercial
Curvature-Directed Crystallization of Poly(vinylidene difluoride) in Nanotube Walls (2003)

Poly(vinylidene difluoride) (PVDF) nanotubes were prepared by wetting of ordered porous templates. We processed either PVDF melts or solutions. The properties of the nanotubes depend strongly on the preparation method. Solution-wetting provides nanotube walls with poor crystallinity. In contrast, nanotube walls obtained by melt-wetting exhibit a pronounced crystallinity indicating the formation of a brushlike wetting layer. The crystallites grow preferentially in the direction of minimal curvature, which corresponds to the long axis of the nanotube. The crystal facets with the highest growth rate are oriented perpendicularly to this axis. For nanotubes consisting of α-PVDF, X-ray diffraction revealed that the b-axis of the unit cell is oriented parallel to the long axis of the nanotube.
Suppressors of<i>zyg-1</i>Define Regulators of Centrosome Duplication and Nuclear Association in<i>Caenorhabditis elegans</i> (2007)

In Caenorhabditis elegans, the kinase ZYG-1 is required for centrosome duplication. To identify factors that interact with ZYG-1, we used a classical genetic approach and identified 21 szy (suppressor of zyg-1) genes that when mutated restore partial viability to a zyg-1 mutant. None of the suppressors render animals completely independent of zyg-1 activity and analysis of a subset of the suppressors indicates that all restore the normal process of centrosome duplication to zyg-1 mutants. Thirteen of these suppressor mutations confer phenotypes of their own and cytological examination reveals that these genes function in a variety of cellular processes including cell cycle timing, microtubule organization, cytokinesis, chromosome segregation, and centrosome morphology. Interestingly, several of the szy genes play a role in attaching the centrosome to the nuclear envelope. We have found that one such szy gene is sun-1, a gene encoding a nuclear envelope component. We further show that the role of SUN-1 in centrosome duplication is distinct from its role in attachment. Our approach has thus identified numerous candidate regulators of centrosome duplication and uncovered an unanticipated regulatory mechanism involving factors that tether the centrosome to the nucleus.
Changes in Heart Rate Variability During Heartfulness Meditation: A Power Spectral Analysis Including the Residual Spectrum (2019)

<b>Background:</b> Meditation refers to a group of practices commonly proposed to treat stress-related conditions and improve overall wellness. In particular, meditation might exert beneficial actions on heart rate variability (HRV) by acting on autonomic tone with an increase in the vagal activity. The effects of heartfulness meditation (HM) on HRV remain poorly defined. <b>Methods:</b> We investigated the effects of HM on HRV in a group of 26 healthy subjects. Subjects were regularly practicing this form of meditation on a daily basis. We assessed the HRV and residual HRV (rHRV) at rest and during meditation. We also used as control a period of respiratory rhythm imposed by an auditory signal, with the imposed breathing rhythm being identical to the spontaneous rhythm recorded during meditation. <b>Results:</b> During deep meditation period, the standard deviation of RR intervals (SD<sub>RR</sub>), coefficient of variation of RR intervals (CV<sub>RR</sub>), and total power (TP) were decreased while the low-frequency power (LFP), normalized LFP (nLFP), and normalized residual LFP (nrLFP) were increased as compared with those at rest, suggesting that the global vagal modulation was suppressed while the baroreflex was increased during deep medication. At the end of meditation, the LFP, residual LFP (rLFP), nLFP, nrLFP, low-/high-frequency power ratio (LHR), and residual LHR (rLHR) were increased while the residual very low-frequency power (rVLFP), normalized high-frequency power (nHFP), and normalized residual HFP (nrHFP) were decreased, as compared with those during paced breathing, suggesting that the vagal modulation was decreased while the sympathetic modulation was increased by deep meditation. During paced breathing period, the SD<sub>RR</sub>, CV<sub>RR</sub>, TP, LFP, rLFP, nLFP, nrLFP, LHR, and rLHR were decreased while nHFP and nrHFP were increased as compared with at rest, suggesting that paced breathing could suppress the sympathetic modulation and enhance the vagal modulation. <b>Conclusion:</b> HM can induce a suppression of global vagal modulation and increased the sympathetic modulation and baroreflex. In addition, paced breathing can suppress the sympathetic modulation and enhance the vagal modulation. Unlike studies using other types of meditation, we did not identify evidence of increased vagal tone during HM.
Simplified detection of the hybridized DNA using a graphene field effect transistor (2017)

Detection of disease-related gene expression by DNA hybridization is a useful diagnostic method. In this study a monolayer graphene field effect transistor (GFET) was fabricated for the detection of a particular single-stranded DNA (target DNA). The probe DNA, which is a single-stranded DNA with a complementary nucleotide sequence, was directly immobilized onto the graphene surface without any linker. The V<sub>Dirac</sub> was shifted to the negative direction in the probe DNA immobilization. A further shift of V<sub>Dirac</sub> in the negative direction was observed when the target DNA was applied to GFET, but no shift was observed upon the application of non-complementary mismatched DNA. Direct immobilization of double-stranded DNA onto the graphene surface also shifted the V<sub>Dirac</sub> in the negative direction to the same extent as that of the shift induced by the immobilization of probe DNA and following target DNA application. These results suggest that the further shift of V<sub>Dirac</sub> after application of the target DNA to the GFET was caused by the hybridization between the probe DNA and target DNA.
Obstacle Tower: A Generalization Challenge in Vision, Control, and Planning (2019)

The rapid pace of recent research in AI has been driven in part by the presence of fast and challenging simulation environments. These environments often take the form of games; with tasks ranging from simple board games, to competitive video games. We propose a new benchmark - Obstacle Tower: a high fidelity, 3D, 3rd person, procedurally generated environment. An agent in Obstacle Tower must learn to solve both low-level control and high-level planning problems in tandem while learning from pixels and a sparse reward signal. Unlike other benchmarks such as the Arcade Learning Environment, evaluation of agent performance in Obstacle Tower is based on an agent's ability to perform well on unseen instances of the environment. In this paper we outline the environment and provide a set of baseline results produced by current state-of-the-art Deep RL methods as well as human players. These algorithms fail to produce agents capable of performing near human level.
Polymer Reaction Engineering V : Quebec, Canada, May 18-23, 2003 (2004)

The Polymer Reaction Engineering conferences are the most important scientific meetings in the area of polymerization reaction research in North America. PRE V provides an update on modern topics of polymer reaction engineering.
A Phase I Trial of B7-Transfected or Parental Lethally Irradiated Allogeneic Melanoma Cell Lines to Induce Cell-Mediated Immunity Against Tumor-Associated Antigen Presented by HLA-A2 or HLA-A1 in Patients with Stage IV Melanoma. National Institutes of Health, Bethesda, Maryland (1995)

T cell lines generated by primary in vitro stimulation with B7-expressing HLA-A2+ melanoma cells lyse HLA-A2+ melanomas, but not non-melanomas that are HLA-A2+. Other data have demonstrated lack of response of these T cell lines against non-HLA-A2 melanomas. These concepts are verified by data from MALME MEL, which is killed, and MALME FIB, which is not. In no case was lysis directed at targets expressing potential allo-antigens (except for HLA-A2+ melanomas). A19 and Aw33 have not been excluded as possible allo-targets (but no data suggests they are). In total, it appears that much of the lytic activity observed in the two T cell lines is directed against HLA-A2-restricted, melanoma-specific antigens.
Empirical evaluation of the tarantula automatic fault-localization technique (2005)

The high cost of locating faults in programs has motivated the development of techniques that assist in fault localization by automating part of the process of searching for faults. Empirical studies that compare these techniques have reported the relative effectiveness of four existing techniques on a set of subjects. These studies compare the rankings that the techniques compute for statements in the subject programs and the effectiveness of these rankings in locating the faults. However, it is unknown how these four techniques compare with Tarantula, another existing fault-localization technique, although this technique also provides a way to rank statements in terms of their suspiciousness. Thus, we performed a study to compare the Tarantula technique with the four techniques previously compared. This paper presents our study---it overviews the Tarantula technique along with the four other techniques studied, describes our experiment, and reports and discusses the results. Our studies show that, on the same set of subjects, the Tarantula technique consistently outperforms the other four techniques in terms of effectiveness in fault localization, and is comparable in efficiency to the least expensive of the other four techniques.
Fibrin Glue versus Vicryl Sutures for Primary Conjunctival Closure in Pterygium Surgery: Long-Term Results (2007)

Purpose: To compare the long-term results of conjunctival closure with fibrin adhesive or Vicryl sutures in pterygium surgery. Methods: The study was performed in 81 patients (81 eyes) with primary nasal pterygium. Surgery in all patients consisted of the bare sclera technique combined with intraoperative administration of mitomycin C 0.02%. Patients were randomized to undergo conjunctival closure with a fibrin adhesive (Quixil) (n = 42) or Vicryl sutures (n = 39). Clinical assessment was performed on postoperative days 1, 3, 10, and 21 and thereafter at 3, 6, and 12 months. All patients completed a questionnaire at each follow-up visit grading pain, discomfort, and satisfaction with the procedure. The groups were compared for operative time, ocular signs and symptoms, overall satisfaction, and recurrence rate. Results: Average operative time was 16 min in the fibrin-glue group and 28 minutes in the Vicryl-suture group (p < 0.05). Significantly less pain and discomfort were noted in the subjects treated with glue than in controls (p < 0.05). Satisfaction was significantly higher in the study group (p < 0.04). There were no complications during follow-up period in the glue-treated patients; one patient in the suture group had a medically treatable corneal dellen. At the end of follow-up, recurrent pterygium developed in five (11.9%) eyes of the fibrin-glue group and in three (7.7%) eyes of the Vicryl-suture group (p < 0.05). Conclusions: The use of fibrin glue in pterygium surgery significantly reduces operative time and patient pain compared with suturing. However, it may be associated with a higher recurrence rate.
Multimodal feature fusion for robust event detection in web videos (2012)

Combining multiple low-level visual features is a proven and effective strategy for a range of computer vision tasks. However, limited attention has been paid to combining such features with information from other modalities, such as audio and videotext, for large scale analysis of web videos. In our work, we rigorously analyze and combine a large set of low-level features that capture appearance, color, motion, audio and audio-visual co-occurrence patterns in videos. We also evaluate the utility of high-level (i.e., semantic) visual information obtained from detecting scene, object, and action concepts. Further, we exploit multimodal information by analyzing available spoken and videotext content using state-of-the-art automatic speech recognition (ASR) and videotext recognition systems. We combine these diverse features using a two-step strategy employing multiple kernel learning (MKL) and late score level fusion methods. Based on the TRECVID MED 2011 evaluations for detecting 10 events in a large benchmark set of ~45000 videos, our system showed the best performance among the 19 international teams.
Establishing template-induced polymorphic domains for API crystallisation: the case of carbamazepine (2015)

Template-induced nucleation of the model compound, Carbamazepine (CBZ), on substrates with different surface chemistries was studied.
Serological, chemical, and structural analyses of the Escherichia coli cross-reactive capsular polysaccharides K13, K20, and K23 (1983)

The Escherichia coli K13, K20, and K23 capsular polysaccharide antigens are serologically related. All of these polysaccharides contain ribose and 2-keto-3-deoxyoctonate in equimolar quantities. The K13 and K20 polysaccharides are partially O-acetylated. A comparison of these polysaccharides after O-deacetylation, by nuclear magnetic resonance and permethylation analysis, showed that these polysaccharides contained the disaccharide repeat unit leads to)-beta-ribofuranosyl-(1 leads to 7)-beta-2-keto-3-deoxyoctonate. They differed in the presence and location of an acetyl moiety. The K13 polysaccharide was O-acetylated at C-4 of the 2-keto-3-deoxyoctonate. The K20 antigen was O-acetylated at C-5 of the ribose moiety. The K23 polymer was nonacetylated. The cross-reactivity of these antigens was demonstrated by tandem-crossed immunoelectrophoresis. Antibodies to K23 could be completely absorbed from OK K23 serum by K13, K20, and K23 antigenic extracts. The K13 and K20 antibodies could be completely absorbed from their respective antisera only by homologous antigenic extracts. Monoclonal antibodies were prepared against a protein conjugate of the K13 polysaccharide. Analyses of the reactions of these antibodies with the three polysaccharides suggest that the K13 polysaccharide has at least three antigenic sites, one of which is common to the K13, K20, and K23 polysaccharides.
Session Description Protocol (SDP) Security Descriptions for Media Streams (2006)

This document defines a Session Description Protocol (SDP) cryptographic attribute for unicast media streams.The attribute describes a cryptographic key and other parameters that serve to configure security for a unicast media stream in either a single message or a roundtrip exchange.The attribute can be used with a variety of SDP media transports, and this document defines how to use it for the Secure Real-time Transport Protocol (SRTP) unicast media streams.The SDP crypto attribute requires the services of a data security protocol to secure the SDP message.
Clonidine in Outpatient Detoxification From Methadone Maintenance (1985)

Inpatient narcotic detoxification with clonidine hydrochloride has been used since 1978. Outpatient withdrawal, potentially more useful, has not been adequately studied. This report describes a double-blind random assignment of 49 methadone hydrochloride-maintained patients whose dose had been lowered to 20 mg. Twenty-five were detoxified using methadone at 1-mg decrements, 24 by abrupt substitution with clonidine. Approximately 40% of both groups achieved successful detoxification, with one third maintaining abstinence over the subsequent six months. The groups were also largely equivalent on withdrawal symptoms, but the clonidine group experienced symptoms in the first half of the study and the methadone group in the second half. Clonidine appears to be a safe and efficacious outpatient treatment for opiate withdrawal, although the results were less favorable than those obtained in open or inpatient studies.
Functional Relationship between Receptor Binding and Biological Activity for Analogs of Mammalian and Salmon Gonadotropin-Releasing Hormones In the Pituitary of Goldfish (Carasslus Auratus)1 (1989)

The relationship between gonadotropin-releasing hormone (GnRH) receptor binding and biological activity in the goldfish pituitary for mammalian and salmon GnRH (sGnRH) analogs with structural modification at the C terminus involving replacement of glycine amide with an alkyl amine and replacement of the Gly6 residue with D amino acids was examined. The GnRH receptor binding data were analyzed with a computerized curve-fitting program (LIGAND) for a single as well as two classes of binding sites; analysis based on one site fit estimated binding affinity and capacity for one class of binding site, and analysis based on two-site fit estimated binding affinity and capacity for two classes of binding sites (high-affinity/low-capacity and low-affinity/high-capacity binding sites). The estimated receptor affinity values were then used to determine the correlation between binding affinity and gonadotropin (GTH)-release potency in vitro. The highest correlation between biological activity and receptor binding affinity was obtained for the high-affinity/low-capacity binding sites and GnRH analogs containing Trp7 and Leu8 residues (i.e., the salmon GnRH structural format) (R = 0.940 +/- 0.150). For the same group of GnRH analogs, there was no significant correlation between the relative GTH-release potency and binding affinity of the low-affinity/high-capacity sites (R = 0.159 +/- 0.434), or that obtained from a one-site fit (R = 0.198 +/- 0.431). Similarly, for mammalian GnRH analogs, significant correlation between binding affinity and biological activity (R = 0.406 +/- 0.049) was only obtained for the high-affinity sites, although the degree of correlation was significantly lower than that obtained for salmon GnRH analogs. The present findings provide strong support for the hypothesis that high-affinity GnRH receptors are involved in the control of GTH release in the goldfish pituitary. In addition, the results demonstrate clearly that the presence of Trp7, Leu8 residues in salmon GnRH molecule, a native peptide in goldfish, is important for recognition of the ligand by the GnRH receptors in the goldfish pituitary, and that structural modifications at positions 6 and 10 in this peptide can increase receptor binding affinity and biological activity at the pituitary level. The most active sGnRH analog identified to date is [D-Arg6, Pro9-NEt]-sGnRH.
Effect of Sarcostemma acidum stem extract on spermatogenesis in male albino rats. (2002)

S. acidum stem extract arrests spermatogenesis in male rats without noticable side effects.
Effect of local PMD and PDL directional correlation on the principal state of polarization vector autocorrelation (2003)

The effect of local PMD and PDL directional correlation is considered for the first time in a single mode fiber communication link. It is shown that the autocorrelation between the real and imaginary part of the complex principal state vector is nonzero in general. Experimental results verifying the local correlation between PMD and PDL directional are reported.
The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib (2012)

Imatinib (1), nilotinib (2) and dasatinib (3) are Bcr-Abl tyrosine kinase inhibitors approved for the treatment of chronic myelogenous leukemia (CML). This review collates information from the journal and patent literature to provide a comprehensive reference source of the different synthetic methods used to prepare the aforementioned active pharmaceutical ingredients (API's).
Biomethanation: Anaerobic fermentation of CO<sub>2</sub>, H<sub>2</sub> and CO to methane (1978)

Abstract Studies to examine the microbial fermentation of coal gasification products (CO 2 , H 2 and CO) to methane have been done with a mixed culture of anaerobic bacteria selected from an anaerobic sewage digestor. The specific rate of methane production at 37°C reached 25 mmol/g cell hr. The stoichiometry for methane production was 4 mmol H 2 /mol CO 2 . Cell recycle was used to increase the cell concentration from 2.5 to 8.3 g/liter; the volumetric rate of methane production ran from 1.3 to 4 liter/liter hr. The biogasification was also examined at elevated pressure (450 psi) and temperature to facilitate interfacing with a coal gasifier. At 60°C, the specific rate of methane production reached 50 mmol/g cell hr. Carbon monoxide utilization by the mixed culture of anaerobes and by a Rhodopseudomonas species was examined. Both cultures are able to carry out the shift conversion of CO and water to CO 2 and hydrogen.