gebhart/patrepeval huggingface dataset:
ON THE EXACT SOLUTIONS TO CONFORMABLE EQUAL WIDTH WAVE EQUATION BY IMPROVED BERNOULLI SUB-EQUATION FUNCTION METHOD (2021)

In this paper, we consider conformable equal width wave (EW) equation in order to construct its exact solutions. This equation plays an important role in physics and gives an interesting model to define change waves with weak nonlinearity. The aim of this paper is to present new exact solutions to conformable EW equation. For this purpose, we use an effective method called Improved Bernoulli Sub-Equation Function Method (IBSEFM). Based on the values of the solutions, the 2D and 3D graphs and contour surfaces are plotted with the aid of mathematics software. The obtained results confirm that IBSEFM is a powerful mathematical tool to solve nonlinear conformable partial equations arising in mathematical physics.
Core Length in Prostate Biopsy: Size Matters (2012)

Needle core length is an important morphometric parameter of transrectal prostate biopsy that directly influences the cancer detection rate. Results suggest a core length of greater than 11.9 mm as a cutoff for quality assurance.
Ber‐EP4 antigen is a marker for a cell population related to the secondary hair germ (2004)

Ber-EP4 is an antibody to a cell membrane glycoprotein of unknown function. In the skin, Ber-EP4 immunoreactivity has been reported to be localized in structures composed of basaloid epithelial cells, i.e. fetal epithelial germ cells, basal cell carcinoma, and trichoepithelioma as well as eccrine or apocrine ducts. In this study, we further characterized the follicular expression of Ber-EP4 immunoreactivity at different stages of the hair cycle of human terminal hair follicles. In addition, to clarify the location of Ber-EP4(+) cells, we compared the Ber-EP4 immunoreactivity with the expression of keratin 15 and keratin 19. Positive staining by Ber-EP4 was found in the lower part of the epithelial strand of late catagen hair follicles, in the secondary hair germ of telogen hair follicles, and in the matrix of early anagen hair follicles but not in any parts of mature anagen hair follicles. In contrast, the follicular expression of keratin 15 detected by using LHK15 antibody was restricted to two distinct parts of anagen hair follicles, i.e. the outer root sheath above the hair bulb and that of the isthmus including the bulge area, and to the outer root sheath of late catagen and telogen hair follicles. The follicular expressions of keratin 19 and that of keratin 15 were apparently superimposed, whereas keratin 15 expression was more extended. The immunoreactivity of LHK15 antibody and antikeratin 19 antibody against the secondary hair germ of telogen follicles was negative or dim. Our results suggest that Ber-EP4 reacts with the secondary hair germ and possibly a cell population related to the secondary hair germ but not with the presumptive stem cell population as revealed immunohistochemically either by the keratin 15 or keratin 19 expression.
Impact experiments with a new technique for acceleration of projectiles to velocities higher than Earth's escape velocity of 11.2 km/s (2010)

The impact velocities of asteroids on Earth and other terrestrial planets can be greater than 10 km/s, and impacts at these high velocities can produce significant effects on the planetary surfaces. However, since macroscopic (>∼0.1 mm) projectiles with an aspect ratio of ∼1 are not easily accelerated to more than 10 km/s in laboratories, there are few detailed experimental studies. In this paper, we demonstrate that impact velocities greater than 10 km/s can be achieved with glass and aluminum projectiles of 0.1–0.3 mm in diameter using a high‐power laser, GEKKO XII‐HIPER at Institute of Laser Engineering, Osaka University. The velocity of the projectiles is estimated based on the images taken by high‐speed X‐ray streak and framing cameras. Projectiles collide into copper or LiF plate targets. The copper plates are recovered for analysis. The sizes of craters on the copper plates are not far from the extrapolations from previous work with lower velocities. A tantalum witness plate placed near the copper plates records a large number of secondary craters from each impact. In the case of the impacts of the LiF plates, we observe two emission lines of Li gas using a spectrometer with a streak camera. Thus, we can simulate the hypervelocity impacts with velocities higher than 10 km/s in laboratories.
Torsional Wave Sensor—A Theory (1986)

Experimental observations suggest that the speed of propagation of torsional waves in a solid, elastic wave guide with a noncircular cross section is inversely proportional to the density of the fluid adjacent to the waveguide. Thus, by measuring the speed of propagation of the torsional wave, one can infer the density of the fluid. Additionally, the above procedure may be utilized to measure, among other things, liquid level and the composition of binary solutions. A simple theory is derived to correlate the torsional wave speed and the fluid density; the theoretical results are also compared with experiments.
DNN Flow: DNN Feature Pyramid based Image Matching (2014)

Image matching especially in category level is a challenge but important problem in vision. The advance of image matching largely depends on the advance of image features. In viewing recent success of learned image feature by DNN, we propose an image matching algorithm based on DNN feature pyramid, named as DNN Flow. The nature of DNN feature pyramid in detecting different level patterns makes it is suitable to match two images in a coarse to fine manner, where top level coarsely matches two images in object level, middle level matches two images in part level, and low level finely matches two images in pixel level. The coarse to fine matching based on DNN feature pyramid is formulated as a series of optimization problems considering the guidance from top level. Extensive experiments demonstrate the superiority of DNN Flow in image matching under challenge variations.
Calmodulin binding to rat adipocyte plasma membrane: characterization and photoaffinity crosslinking of calmodulin to binding proteins (1982)

[125I]Calmodulin binding to isolated rat adipocyte plasma membranes has been characterized, and the calmodulin binding proteins associated with the membrane have been identified by use of the photoaffinity cross-linker N-hydroxysuccinimidyl 4-azidobenzoate. Total binding of [125I]calmodulin to plasma membranes was assayed by a centrifugation method and found to be calcium dependent, requiring 2.2 microM free calcium for half-maximal binding. Total binding was curvilinear with time, plateauing at 30 min. In addition, calmodulin binding was demonstrated to be both saturable (1700 pmol/mg of membrane protein) and exchangeable. Additional calmodulin binding sites were not produced by further ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA) treatment of membranes prepared in the presence of ethylenediaminetetraacetic acid (EDTA). Eight specific calmodulin binding protein complexes were identified by use of the photocovalent cross-linking agent. Results obtained with photocovalent cross-linking were similar to those obtained in the total calmodulin binding assays. The formation of the calmodulin binding protein complexes was dependent on time and calcium concentration. The integration of these two techniques provides a powerful tool for studying calmodulin-regulated proteins.
Pharmacokinetics and pharmacodynamics of cloprednol. (1996)

The pharmacokinetics and pharmacodynamics of cloprednol after oral administration in doses of 2.5 to 15 mg to healthy volunteers were determined. The half-life of cloprednol ranged from 1.8 h to 2.7 h, the oral clearance (CL/F) was determined to be 15-22 l/h. Since cloprednol shows nonlinear plasma protein binding, the plasma concentrations were converted to their free, unbound concentrations for the PK/PD-analysis. Due to this nonlinearity, the half-life of free, unbound cloprednol was shorter than that of the total drug. For the assessment of pharmacodynamics, differential white blood cell counts were obtained over 24 hours. An integrated pharmacokinetic-pharmacodynamic (PK/PD) approach using a modified Emax-model was applied to link unbound corticosteroid concentrations to the effect on lymphocytes and granulocytes. The E50 value for unbound cloprednol ranged from 3.6 to 4.7 ng/ml and 1.2 to 4.6 ng/ml for granulocytes and lymphocytes, respectively. The PK/PD model allowed a good prediction of the observed effects and was consistent with reported values for glucocorticoid receptor binding affinities for cloprednol.
Description of a new disposable uterine sampler (the Accurette) for endometrial cytology and histology. (1982)

A disposable, collapsible curette made from a special plastic material, devised by the author for obtaining cytological and histological samples of the uterine endometrium, is described. A simple syringe for vacuum aspiration is incorporated with the instrument. Its manifold advantages include simplicity of design and ease of application, making little demand on the operator. No additional apparatus is required for its use in outpatient clinics or as an office procedure.
<title>Eight-channel video broadcast feed service using free-space optical wireless technology at the Sydney 2000 Olympic Games</title> (2001)

12 Terrestrial 1550 nm WDM free-space optical communication systems have been demonstrated to provide a viable means to transport data, voice and video channels for point-to-point applications without the use of optical fiber. Key features of free-space optical transmission systems are their ability to utilize present day telecommunication components such as: laser diode transmitters, high-power optical amplifiers operating within the 1550 nm optical transmission window and high-sensitivity optical receivers designed for multi-Giga- bit data rates. In this paper, we report on details of the world's first field test, demonstrating real time video transmission of eight uncompressed standard-definition (SD) video channels operating at an aggregate data rate of 1.485 Gb/s over a 0.89 km terrestrial free-space link. This data link was used in support of the 2000 Olympic games held recently in Sydney, Australia. Results from this eight- channel SD terrestrial free-space laser communications systems are presented. The transmission system operated error-free continuously from September 14, 2000 until October 1, 2000, twenty-four hours a day, throughout the coverage of the games. Modeling results predict that free- space SD video transmission systems can be designed and operated over significant link distances under nominal visibility conditions.
Induction of GTP cyclohydrolase I by bacterial lipopolysaccharide in the rat (1993)

A 2- to 3-fold increase of GTP cyclohydrolase I (E.C. 3.5.4.16), the key enzyme of tetrahydrobiopterin biosynthesis from GTP, was observed in cerebellum, remaining brain, liver, spleen, and adrenal gland of rats treated with a single dose of lipopolysaccharide (LPS). This led to increased biopterin levels in tissues but not in plasma. Parallel induction of nitric oxide (NO) synthase was indicated by a 10- to 100-fold increase of plasma nitrate levels 6 and 12 hours after injection of LPS. Furthermore, systolic blood pressure was reduced significantly by 23%. Our results demonstrate induction of tetrahydrobiopterin biosynthesis after LPS treatment in vivo.
C-Cell Hyperplasia (1989)

Department of Pathology Department of Endocrinology & Metabolism Roger Williams General Hospital Brown University Program in Medicine Providence, RI 02908
New Compounds. Crotyl Malonate, Methylvinylcarbinyl Malonate and Cinnamyl Cyanoacetate (1944)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Compounds. Crotyl Malonate, Methylvinylcarbinyl Malonate and Cinnamyl CyanoacetateWalter Kimel and Arthur CopeCite this: J. Am. Chem. Soc. 1944, 66, 9, 1613–1614Publication Date (Print):September 1, 1944Publication History Published online13 November 2002Published inissue 1 September 1944https://pubs.acs.org/doi/10.1021/ja01237a602https://doi.org/10.1021/ja01237a602research-articleACS PublicationsRequest reuse permissionsArticle Views50Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Studies on <i>Myxosoma cartilaginis</i> n. sp. (Protozoa: Myxosporidea) of Centrarchid Fish and a Synopsis of the <i>Myxosoma</i> of North American Freshwater Fishes (1965)

SYNOPSIS. Myxosoma cartilaginis n. sp. is described from the cartilage of Lepomis macrochirus (bluegill), L. cyanellus (green sunfish) and Micropterus salmoides (largemouth black bass). The development of the parasite is described from naturally infected fish which were held in spore‐free water after infection. The sporoplasm invades cartilage, and becomes a multi‐nucleate trophozoite which forms pansporoblasts, each of which produces 2 to 4 spores. The first spores appear in 7 weeks. The histopathology in the above fish consists at first of little cellular reaction, but after 4 to 5 months epithelioid granulomas appear around some of the spore masses. Cartilage liquefaction is present around the parasites for at least 5 weeks. Eosinophilic globules are present in cartilage cells adjacent to the lesions. Diffuse infiltration of the spores from the lesions is described. Of 24 chemicals tested for polar filament extrusion, potassium hydroxide gave the best results. An illustrated synopsis of the Myxosoma of North American fishes is given. Included is some additional information and illustrations of M. hoffmani Meglitsch, 1963. Also included is a table showing the hosts, site of infection, geographic location, spore and polar capsule sizes.
Regulation of Acetoacetyl‐CoA in Isolated Perfused Rat Hearts (1981)

The role of ketone bodies and long-chain fatty acids in regulating myocardial content of acetoacetyl-CoA was examined in isolated perfused hearts from fed rats. Addition of 10 mM acetoacetate to a perfusion medium containing 5.5 mM glucose as exogenous substrate resulted in a sevenfold increase of cardiac acetoacetyl-CoA content. Inclusion of 0.75--0.94 mM palmitate in the perfusate did not augment the basal level of acetoacetyl-CoA nor did it influence the already elevated content of the metabolic intermediate shown to exist in the presence of acetoacetate alone. In addition to the observed increase in myocardial acetoacetyl-CoA, a decrease in free carnitine in hearts perfused with acetoacetate was accompanied by elevated ratios of both acetylcarnitine/carnitine and long-chain fatty acylcarnitine/carnitine. Addition of palmitate in the presence of acetoacetate resulted in a further diminution of myocardial free carnitine leading to a further elevation of the long-chain fatty acylcarnitine/carnitine ratio when compared to hearts perfused with the ketone body alone. The changes in myocardial CoA and carnitine and their intermediates in hearts perfused with acetoacetate either alone or in combination with palmitate indicate that ketone bodies can divert fatty acids away from oxidation and toward esterification as triacylglycerols. Even though the interrelationships between ketones and myocardial fatty acid metabolism have not been fully characterized, a role for ketone bodies in promoting the increase in myocardial acetoacetyl-CoA found in diabetic ketoacidosis has been clearly defined.
Ultra‐performance liquid chromatography coupled with electrospray ionization/quadrupole time‐of‐flight mass spectrometry for the rapid analysis of constituents in the traditional <scp>C</scp>hinese medical formula <scp>D</scp>anggui San (2013)

In this work, ultra-performance LC with ESI quadrupole TOF-MS (UPLC-ESI-Q-TOF-MS) and automated MetaboLynx analysis was used to rapidly separate and identify the chemical constituents of Danggui San, a traditional Chinese medical formula. The analysis was performed on a Waters UPLC BEH C18 column using a gradient elution system. A hyphenated ESI and Q-TOF analyzer was used for the determination of the accurate mass of the protonated or deprotonated molecule and fragment ions in both positive and negative modes. Based on retention times, accurate mass, and the mass spectrometric fragmentation characteristics, a total of 47 compounds distributed over the chemical groups of phthalides, flavonoids, monoterpene glycosides, sesquiterpenoids, phenolics, and alkaloids, were simultaneously separated within 18 min and identified or tentatively elucidated in Danggui San for the first time. UPLC-ESI-Q-TOF-MS analysis revealed the complexity of the chemical composition of this formula. The method developed is rapid, accurate, reliable, and highly sensitive to characterize the chemical constituents of Danggui San.
Overview of field-flow fractionation (1997)

Foremost among J.C. Gidding's many contributions to separation science is the invention and development of field-flow fractionation. This article is a nonmathematical overview of field-flow fractionation with a discussion of general principles and the basic subtechniques of this separation method. A brief review is given of some of the molecular and particle separations and characterizations which have been and are currently being used which illustrate the broad potential of this method. Since field-flow fractionation requires small samples for optimum performance, the use of SPLITT for obtaining sized materials in up to gram quantities is also discussed. © 1997 John Wiley & Sons, Inc. J Micro Sep 9: 151–162, 1997
Efficient Lane and Vehicle Detection with Integrated Synergies (ELVIS) (2014)

On-road vehicle detection and lane detection are integral parts of most advanced driver assistance systems (ADAS). In this paper, we introduce an integrated approach called Efficient Lane and Vehicle detection with Integrated Synergies (ELVIS), that exploits the inherent synergies between lane and on-road vehicle detection to improve the overall computational efficiency without compromising on the robustness of both the tasks. Detailed evaluations show that the vehicle detection component of ELVIS shows at least 50% lesser false alarms with equal or better detection rates, and reducing the computational costs by over 90% as compared to state-of-the-art vehicle detection methods. Similarly, the lane detection component shows more reliable lane feature extraction with average computation costs that are at least 35% lesser than existing techniques.
18-GHz, 4.0-aJ/bit Operation of Ultra-Low-Energy Rapid Single-Flux-Quantum Shift Registers (2012)

We demonstrate rapid single-flux-quantum (RSFQ) circuits with reduced energy consumption by lowering the driving voltages and critical currents of Josephson junctions (JJs). At lowered voltages, the energy statically consumed by bias resistors (which is dominant in RSFQ circuits) is reduced. In addition, we show that when RSFQ circuits are driven by lowered constant voltages, the dynamic energy consumption resulting from the switching of JJs is reduced because of the suppression of the amplitudes of the signal voltage pulses, even though the switching speed becomes slower. Utilization of miniaturized JJs with smaller critical currents also leads to the reduction of static and dynamic energy consumption without decreasing the switching speed. We have designed and tested ultra-low-energy 8-bit shift registers, and verified the correctness of high-speed operations up to 18 GHz. The average energy consumption, including that at the bias resistors, was measured at 4.0 aJ/bit, which represents an energy efficiency two orders of magnitude better than that of standard RSFQ circuits.
Compressive Sensing Applied to Full-wave Form Inversion (2009)

Full-waveform inversion's high demand on computational resources forms, along with the non-uniqueness problem, the major impediment withstanding its widespread use on industrial-size datasets. Turning modeling and inversion into a compressive sensing prob
The endothelial cytoskeleton as a target of electroporation-based therapies (2006)

Electroporation-based therapies, such as electrochemotherapy and electrogene therapy, result in the disruption of blood vessel networks in vivo and cause changes in blood flow and vascular permeability. The effects of electroporation on the cytoskeleton of cultured primary endothelial cells and on endothelial monolayer permeability were investigated to elucidate possible mechanisms involved. Human umbilical vein endothelial cells (HUVECs) were electroporated in situ and then immunofluorescence staining for filamentous actin, beta-tubulin, vimentin, and VE-cadherin as well as Western blotting analysis of levels of phosphorylated myosin light chain and cytoskeletal proteins were performed. Endothelial permeability was determined by monitoring the passage of FITC-coupled dextran through endothelial monolayers. Exposure of endothelial cells to electric pulses resulted in a profound disruption of microfilament and microtubule cytoskeletal networks, loss of contractility, and loss of vascular endothelial cadherin from cell-to-cell junctions immediately after electroporation. These effects were voltage dependent and reversible because cytoskeletal structures recovered within 60 min of electroporation with up to 40 V, without any significant loss of cell viability. The cytoskeletal effects of electroporation were paralleled by a rapid increase in endothelial monolayer permeability. These results suggest that the remodeling of the endothelial cytoskeleton and changes in endothelial barrier function could contribute to the vascular disrupting actions of electroporation-based therapies and provide an insight into putative mechanisms responsible for the observed increase in permeability and cessation of blood flow in vivo.
Does Chronic Hyperinsulinemia Cause Hypertension? (1989)

The aim of this study was to determine whether chronic hyperinsulinemia, comparable to that found in obesity-associated hypertension, causes sustained increases in mean arterial pressure (MAP) or potentiates the hypertensive effects of angiotensin II (ANG II). Insulin infusion (0.5 or 1.0 mU/kg/min, IV), with plasma glucose held constant by IV glucose infusion, for seven to 28 days raised plasma insulin by five- to ten-fold, but did not significantly change MAP in dogs with reduced kidney mass that were maintained on high sodium intake. In dogs infused with ANG II to cause mild hypertension, insulin for 28 days did not potentiate the hypertension. Insulin infusion did, however, cause modest sodium retention during the first few days of infusion. These findings suggest that additional factors besides hyperinsulinemia per se are responsible for obesity-associated hypertension.
Isolation and Identification of Ascomycin (2010)

FW99802 was isolated from the fermentation extract that including tacrolimus by macroporous adsorptive resin chromatography.The crystalline powder was obtained with high purity(98%) after recrystallization.The structure of FW99802 was determinded to be ascomycin by physico-chemical properties and spectral analyses.