gebhart/patrepeval huggingface dataset:
Adaptive Feedback of the Channel Information for Beamforming in IEEE 802.11ax WLANs (2019)

In this paper, we propose an adaptive beamforming matrix feedback scheme, which guarantees the best packet error rate (PER) by selecting the beamforming matrix between singular value decomposition (SVD) and geometric mean decomposition (GMD) based beamforming matrices. The physical layer (PHY)-abstraction is utilized for joint PER prediction and modulation and coding scheme (MCS) level selection. In addition, a low complexity GMD is proposed where the iterative GMD process is converted to 2×2 block-wise GMD without iteration. Each 2×2 GMD is further simplified to remove the square-root and division operators for easy hardware implementation. The simulation is performed extensively via a 802.11ax link-level simulator. The results show that the proposed adaptive feedback scheme provides a significant performance gain in comparison to the conventional SVD- or GMD-based beamforming matrix feedback scheme. Also, the proposed GMD has an advantage in both complexity and PER performance when the number receive antenna is more than two.
[On the synthesis of compounds with beta-adrenergic activity (author's transl)]. (1980)

It is reported of the synthesis of 1-phenoxy-2-hydroxy-3-aminopropane derivatives with different substituents in the phenoxy residue as well as in the amino group. The potency and the efficacy of these derivatives depend on the substituents. By the introduction of the arylamino-ethyl residue into the nitrogen atom, beta-adrenergic locking agents with marked agonistic activity are obtained.
Fibroblast growth factor signaling in skeletal development and disease (2015)

Fibroblast growth factor (FGF) signaling pathways are essential regulators of vertebrate skeletal development. FGF signaling regulates development of the limb bud and formation of the mesenchymal condensation and has key roles in regulating chondrogenesis, osteogenesis, and bone and mineral homeostasis. This review updates our review on FGFs in skeletal development published in Genes & Development in 2002, examines progress made on understanding the functions of the FGF signaling pathway during critical stages of skeletogenesis, and explores the mechanisms by which mutations in FGF signaling molecules cause skeletal malformations in humans. Links between FGF signaling pathways and other interacting pathways that are critical for skeletal development and could be exploited to treat genetic diseases and repair bone are also explored.
Subsampling the search space for fast block motion estimation (2002)

An new algorithm for block motion compensation is presented. Block motion compensation algorithms trade speed for accuracy. The new algorithm subsamples the search space for speed and uses the successive elimination algorithm (SEA) to further constrain the search space. Simulation results show that the algorithm performs similarly to the SEA algorithm and is computationally faster.
A phase II randomized, placebo-controlled, double-blind study of the efficacy and safety of RC-1291 (RC) for the treatment of cancer cachexia (2007)

9133 Background: Cancer cachexia is closely correlated with poor outcome and poor survival. RC is an oral ghrelin mimetic with orexigenic and anabolic activity. Methods: A phase II trial enrolled 81 patients with cancer, performance scores of 0–2, and weight loss of 5% or more within 6 months prior to enrollment at 17 sites in the US. Patients were randomized to treatment with two placebo (PL) or two 25 mg RC capsules taken once daily for 12 weeks. Outcome measures included lean body mass (LBM), total body mass (TBM) by DEXA (central reading), scale weight, handgrip strength (HS) and QOL measures. Biochemical markers included IGF-1 and IGFBP-3. In the per protocol analysis (32 RC, 28 PL) more than 20 cancer types were represented; the most common were lung (n=13) and colorectal cancer (n=15). The two treatment groups were balanced at baseline except for (RC vs PL, respectively): gender (66 % male vs 57 %), TBM (60.9 kg vs 65.3 kg), and HS (53.8 kg vs 56.6 kg). The analyses (repeated measures ANOVA without imputation) included all available data from the patients. Results: TBM and LBM (primary endpoint at 8 wks) were significantly increased vs. PL at wks 4 and 8 and at wks 4, respectively. The magnitude of the increase vs. baseline was stable from wk 4 through wk 12 during RC treatment for both TBM and LBM. HS was increased at significantly at wk 8. IGF-1 and IGFBP-3 significantly increased at wks 4, 8, and 12. No significant differences were found on the QOL or scale weight measures. RC was well tolerated. Patients having any AEs were 96% vs 87% and SAEs were 32% and 26% for RC and PL, respectively. The percent of patients and types of AEs were similar; possible exceptions included cardiac events and infections (11% vs 3% and 30% vs 42%, RC vs PL, respectively). Conclusions: In this randomized, double-blind, placebo-controlled trial, RC treatment led to improvements in LBM, TBM and HS. RC-1291 is a promising potential therapeutic agent for the treatment of cancer cachexia. No significant financial relationships to disclose.
EFFECTS OF RIBONUCLEIC ACID ON MEMORY DEFECT IN THE AGED (1963)

1. We have shown again and with a larger group of patients the effects of RNA administered intravenously upon the memory performance of patients suffering from organic memory defect. 2. We have demonstrated that it is possible to make a beginning in the task of analyzing which mechanisms within the memorial process are particularly favorably affected by RNA. 3. Thus far the indications are: i) that RNA acts upon the mechanism for retention, ii) that there is possibly a hitherto unrecognized mechanism for the storage of data by classification, iii) that there are other as yet unidentified mechanisms within the memorial process apart from retention which are favourably affected by RNA.
The first co-ordinatively unsaturated Group 8 allenylidene complexes: insights into Grubbs’ vs. Dixneuf–Fürstner olefin metathesis catalysts (1999)

The reactions of [MCl2(PPh3)3] with HCCCPh2OH provided [MCl2(CCCPh2)(PPh3)2] (M = Ru 1a or Os 1b) the first examples of co-ordinatively unsaturated allenylidene complexes of Group 8 metals. The phosphine ligands of 1a are labile and readily replaced by PCy3 to give [RuCl2(CCCPh2)(PCy3)2] 1c. Heating 1a with NaPF6 in chloroform gave the known bimetallic salt [Ru2(µ-Cl)3(CCCPh2)2(PPh3)4]PF6 2·PF6. The reaction of 1a with carbon monoxide provided [RuCl2(CCPh2)(CO)(PPh3)2] 3 which may also be prepared from [RuCl2(CO)(dmf)(PPh3)2] and HCCCPh2OH. The first macrocycle coligated allenylidene complex [RuCl(CCCPh2)(PPh3)([9]aneS3)]Cl 4·Cl ([9]aneS3 = 1,4,7-trithiacyclononane) was obtained from the reaction of 1a with [9]aneS3. Alternatively, 4·PF6 is also obtained by treating [RuCl2(PPh3)([9]aneS3)] sequentially with NaPF6 in acetonitrile followed by HCCCPh2OH. The reaction of 1a with dppe and NaPF6 yielded the known salt trans-[RuCl(CCCPh2)(dppe)2]PF6 5·PF6. The complex [RuCl(CCCPh2)(PCy3){HB(pz)3}] 6 (pz = pyrazol-1-yl) was obtained from the reaction of 1c with K[HB(pz)3], whilst the related benzylidene complex [RuCl(CHPh)(PCy3){HB(pz)3}] 7 was obtained similarly from [RuCl2(CHPh)(PCy3)2] and K[HB(pz)3]. Heating [Ru2(µ-Cl)2Cl2(η-cym)2] (cym = iPrC6H4Me-4) with PCy3 and HCCCPh2OH in refluxing benzene provided a mixture of 1c and the bimetallic complex [Ru2(µ-Cl2)Cl2(CCCPh2)(η-cym)] 8 and other unidentified products. The complex 8 may however be obtained quantitatively from the reaction of 1c with [Ru2(µ-Cl)2Cl2(η-cym)2]. These results suggest that the active species in ring-closure olefin metathesis processes mediated by the allenylidene pre-catalyst [RuCl(CCCPh2)(PCy3)(η-cym)]+ in non-polar arene solvents may be allenylidene analogues of the Grubbs’ alkene metathesis catalyst, viz. 1c and 8.
Polymerization site in the .beta. chain of fibrin: mapping of the B.beta.1-55 sequence (1991)

The formation of a fibrin clot occurs through binding of putative complementary sites, called fibrin polymerization sites, located in the NH2- and COOH-terminal domains of fibrin monomer molecules. In this study, we have investigated the structure of the NH2-terminal fibrin polymerization site by using fibrinogen-derived peptides and fragments. Fibrinogen was digested with Crotalus atrox protease III, to two major molecular species: a Mr 325,000 derivative (Fg325) and a peptide of Mr 5000. The peptide and its thrombin-cleavage product were purified by ion-exchange and reverse-phase HPLC; the authenticity of the B beta 1-42 and beta 15-42 peptides, respectively, was confirmed by amino acid sequencing. Since Fg325 had decreased thrombin coagulability, we addressed the question of whether the peptide B beta 1-42 contained a fibrin polymerization site. In order to identify and map the site, the peptides B beta 1-42 and beta 15-42 were tested for their ability to inhibit fibrin monomer polymerization. In addition the following peptides prepared by chemical synthesis were also tested: beta 15-18, beta 15-26, beta 24-42, beta 40-54, beta 50-55, and alpha 17-19-Pro. While B beta 1-42 had no inhibitory activity, the peptide devoid of fibrinopeptide B, beta 15-42, was a strong inhibitor. The peptides beta 15-18, beta 15-26, and beta 15-42 decreased the rate of fibrin polymerization by 50% at a molar excess of the peptide to fibrin monomer of 500, 430, and 50, respectively. The peptides beta 24-42, beta 40-54, and beta 50-55 were inactive.(ABSTRACT TRUNCATED AT 250 WORDS)
Thermal Diffusion Separation of Different Gases of the Same Molecular Weight (1940)

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An implantable neural probe with monolithically integrated dielectric waveguide and recording electrodes for optogenetics applications (2013)

This minimally invasive, complete monolithic integration provides unmatched spatial precision and scalability for future optogenetics studies at deep brain regions with high neuronal density.
Video-based construction vehicles detection and its application in intelligent monitoring system (2016)

While vehicle detection on highways has been reported before, to the best of our knowledge, intelligent monitoring system that aims at detecting hydraulic excavators and dump trucks on state-owned land has not been explored thoroughly yet. In this paper, we present an automatic, video-based algorithm for detecting hydraulic excavators and dump trucks. Derived from lessons learned from video processing, we proposed methods for foreground detection based on an improved frame difference algorithm, and then detected hydraulic excavators and dump trucks in the respective region of interest. From our analysis, we proposed methods based on inverse valley feature of mechanical arm and spatial-temporal reasoning for hydraulic excavator detection. In addition, we explored dump truck detection strategies that combine structured component projection with the spatial relationship. Experiments on real-monitoring sites demonstrated the promising performance of our system.
Semiconductor nanoparticles: new building blocks for polymer-microelectronics? (2002)

The following paper describes the new possibilities for applications, resulting from the combination of luminescent semiconductor nanoparticles (so-called quantum dots) and conducting polymers. First the theory will be briefly introduced, then three examples will be described and discussed: quantum dot light-emitting diodes (QDLEDs), generally quantum dot/conducting polymer composites and, finally, quantum dot photoelectric devices. By these examples, the state of the art is described and future possibilities are shown.
Control of structural defects in group III V N alloys grown on Si (2002)

The key issues for growing III–V compound layers, free of structural defects, on Si substrates are clarified. The technologies for overcoming the fundamental problems have been developed. As a result, it has been clarified that dislocation-free III–V–N alloys can be grown on Si substrates whose lattice constants are matched to those of Si. Device structures of the GaAsPN/GaPN quantum well structure and the Si/GaPN/Si structure have been successfully grown on a Si (100) substrate covered with a thin GaP initial layer. The grown layers and hetero-interfaces contained no threading dislocations and no misfit dislocations, respectively. Neither stacking faults nor anti-phase domains were observed. A key issue for application to novel devices is the increase in nitrogen composition without degrading optical and electrical properties.
Factors affecting the release and activity of tissue thromboplastin (1980)

Conference Article| February 01 1980 Factors affecting the release and activity of tissue thromboplastin FRIEDA JORDAN; FRIEDA JORDAN 1Department of Biochemistry, Queen Elizabeth College, University of London, Campden Hill Road, London W8 7AH, U.K. Search for other works by this author on: This Site PubMed Google Scholar ROY M. HOWELL ROY M. HOWELL 1Department of Biochemistry, Queen Elizabeth College, University of London, Campden Hill Road, London W8 7AH, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1980) 8 (1): 123–124. https://doi.org/10.1042/bst0080123 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation FRIEDA JORDAN, ROY M. HOWELL; Factors affecting the release and activity of tissue thromboplastin. Biochem Soc Trans 1 February 1980; 8 (1): 123–124. doi: https://doi.org/10.1042/bst0080123 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1980 Biochemical Society1980 Article PDF first page preview Close Modal You do not currently have access to this content.
Can you hear me now? A call detail record based end-to-end diagnostics system for mobile networks (2019)

Automation of mobile network fault diagnostics and troubleshooting is critical for successful transformation to new network technologies such as 5G and core Network Function Virtualization (NFV). This paper presents a decision tree-based call detail record (CDR) labeling process, which is used to construct an automated end-to-end diagnostics system for mobile network faults. The presented diagnostics system will enable the utilization of automated troubleshooting systems, and the execution of automated corrective actions in third party systems such as Self-Organizing Network (SON) and NFV domain orchestrator.
Multifunctional microbubbles and nanobubbles for photoacoustic imaging (2011)

Photoacoustic imaging is an emerging imaging modality for noninvasive detection of tissue structural and functional anomalies. Multifunctional microbubbles (MBs) and nanobubbles (NBs) are contrast agents integrating multiple disease-targeting, imaging and therapeutic functions. Multifunctional MBs and NBs represent an enabling technology for many potential applications in the field of photoacoustic imaging. Highly absorbing optical contrast agents, such as gold nanoparticles, India ink and Indocyanine Green, can be encapsulated in MBs and NBs for stable absorption properties and multimodal imaging contrasts. The surface of MBs and NBs can be modified for high disease-targeting affinity, reduced immunogenicity and prolonged circulation lifetime. Low boiling point perfluorocarbon compounds can be encapsulated in MBs and NBs for selective activation by external energy sources. The activation of these MBs and NBs may introduce significant contrast enhancement and facilitate a variety of potential clinical applications, such as image-guided drug delivery and therapeutic margin assessment. MB and NB enhanced photoacoustic imaging is still in its infancy. Further development and validation works are necessary for successful translation of the technology from the benchtop to the bedside.
Hybrid polyMOF Materials Prepared by Combining an Organic Polymer with a MOF and Their Application for Solar Thermal Energy Storage (2021)

The combination of metal–organic frameworks (MOFs), namely UiO-66, with polyethylene glycol (PEG) polymers yields hybrid polyMOF materials, which show unique morphology with tunable characteristics of UiO-66. Mixed MOF-PolyMOFs (referred to as UiO-66) are utilized as a support material for the preparation of shape stabilized phase change materials (ss-PCM). Three ss-PCMs were synthesized with the composition of PEG-0.5 g/UiO-66–0.2 g (PU-0.5), PEG-0.7 g/UiO-66–0.2 g (PU-0.7), and PEG-1.0 g/UiO-66–0.2 g (PU-1.0) and tested for solar thermal energy storage. The high PEG retaining capacity of UiO-66 is promising for thermal storage applications. The latent heat value of the PU-0.5 PCM is 146 J/g, which is considerably higher than that of PCMs based on similar materials. Besides, PU-0.5PCM has a high energy storage efficiency, high thermal energy capability, and exceptional shape-stabilized PCM properties. Thermal conductivity of PU-0.5 PCM is 0.51 W/mK, which is higher than that of most of the reported paraffin- and PEG-based PCMs. PU-0.5 PCM remains stable even when subjected to 200 freezing and melting cycles. In addition, the use of carbon nanotubes (CNTs) to improve the thermal conductivity of PEG-UiO-66 has been investigated. For comparison, the effect of PEG of various MWs (molecular weights) was also calculated.
Cotranslational secretion of diphtheria toxin and alkaline phosphatase in vitro: involvement of membrane protein(s) (1980)

Crude messenger ribonucleic acid fractions isolated from Corynebacterium diphtheriae and Escherichia coli were translated in an E. coli in vitro protein-synthesizing system and yielded precursors of the secreted proteins diphtheria toxin and alkaline phosphatase, respectively. Addition of inverted E. coli inner membrane vesicles to the system during the initial stages of translation resulted in the intravesicular segregation of mature diphtheria toxin and alkaline phosphatase. Outer membrane vesicles or inner membrane vesicles whose cytoplasmic surfaces had been treated with pronase could not mediate transmembrane transfer of diphtheria toxin or alkaline phosphatase. However, inner membrane vesicles isolated from E. coli spheroplasts which had been treated with pronase and inner membrane vesicles complexed with ribosomes during pronase treatment were functional in transmembrane transfer. At temperatures below the phase transition of E. coli membranes, no intravesicular segregation of alkaline phosphatase or diphtheria toxin was observed. The precursor forms of each protein accumulated free from the vesicles. These results suggest that an inner membrane protein, exposed on the cytoplasmic surface, plays an integral role in secretion.
Relevance of the rates of PCNA, Ki-67 and p53 expression according to the epithelial compartment in cervical lesions. (2001)

In order to assess further biological evidence for similarities among the "diagnostic classes" of cervical lesions, which are now a matter of international discussion in the search for a uniform classification, the purpose of this study was to characterize the immunoexpression of cell proliferation markers (proliferating cell nuclear antigen, PCNA and Ki-67) and protein p53. Each marker was individually quantified in basal, intermediate, and superficial epithelial compartments presenting chronic cervicitis (CC) accompanied by the cytopathic effects of infection by human papillomavirus (CCHPV) or not (CC), as well as in cervical intraepithelial neoplasia (CIN) grades I, II, and III. A total of 100 patients were evaluated and the positive nuclei were counted separately, including all extensions of the available epithelium. The percentage of PCNA- and Ki-67-positive cells increased with increasing grade of the cervical lesions, although PCNA immunoreactivity was always greater than the immunoreactivity observed with Ki-67 antigen. The immunoexpression of p53 protein was found to be weak, with no remarkable behavior in any specific "diagnostic class". The differences in cell proliferation markers found herein further emphasize the progressive loss of epithelial layer organization in the course of the development of preneoplastic changes in cervical squamous epithelium. Furthermore, difficulties in morphologically distinguishing "borderline lesions" persist when cell cycle markers are studied, further supporting the suggestion to consider the lesions of CCHPV and CIN I together as only one diagnostic class. Conversely, the different immune profile found between CIN II and III further supports the validity of the subdivision of CIN into three groups.
Cell Selection in 4G Cellular Networks (2008)

Cell selection is the process of determining the cells that provide service to each mobile station. Optimizing these processes is an important step towards maximizing the utilization of current and future cellular networks. In this paper we study the potential benefit of global cell selection versus the current local mobile SNR-based decision protocol. In particular, we study the new possibility that is feasible in OFDMA-based systems, of satisfying the minimal demand of a mobile station simultaneously by more than one base station. We formalize the problem as an optimization problem, called the all-or-nothing demand maximization problem, and show that when the demand of a single mobile station can exceed the capacity of a base station, this problem is not only NP-hard but also cannot be approximated within any reasonable factor. In contrast, under the very practical assumption that the maximum required bandwidth of a single mobile station is at most an r-fraction of the capacity of a base station, we present two different algorithms for cell selection. The first algorithm guarantees a satisfaction of at least a 1- r r fraction of an optimal assignment, where a mobile station can be covered simultaneously by more than one base station. The second algorithm guarantees a satisfaction of at least a 1-r/1-r fraction of an optimal assignment, while every mobile station is covered by at most one base station. Using an extensive simulation study we show that the cell selections determined by our algorithms achieve a better utilization of high-loaded capacity-constrained future 4G networks than the current SNR- based scheme. Specifically, our algorithms are shown to obtain up to 20% better usage of the network's capacity, in comparison with the current cell selection algorithms.
Membrane introduction mass spectrometry (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMembrane Introduction Mass SpectrometryTapio Kotiaho, Frants R. Lauritsen, Tarun K. Choudhury, R. Graham Cooks, and George T. TsaoCite this: Anal. Chem. 1991, 63, 18, 875A–883APublication Date (Print):September 15, 1991Publication History Published online30 May 2012Published inissue 15 September 1991https://pubs.acs.org/doi/10.1021/ac00018a717https://doi.org/10.1021/ac00018a717research-articleACS PublicationsRequest reuse permissionsArticle Views518Altmetric-Citations130LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts