gebhart/patrepeval huggingface dataset:
Prevention of genetic fa/fa obesity with an ephedrine-methylxanthines thermogenic mixture (1987)

A thermogenic mixture containing ephedrine and methylxanthines was administered to 8-wk-old genetically obese fa/fa rats (O-E/Mx group) for a period of 15 wk. Their energy balance and the final body composition were compared with an untreated ad libitum-fed (O-AL) group, as well as to other fa/fa obese animals that were either pair fed to lean controls (O-PF group), or that were food restricted to such an extent they maintained a similar body weight to that of lean animals (O-WF group). Energy intake was elevated above lean or O-PF levels by approximately 27 and 10% in the O-AL and O-E/Mx groups, respectively, but lower by 18% in the O-WF group. Energy expenditure, compared with the lean values, was 10% higher in both the O-AL and O-E/Mx groups, but reduced by 13 and 30% in the O-PF and O-WF groups, respectively. The gain in body energy and the efficiency of energy deposition remained elevated above the lean values by 2.3- to 3.5-fold in the O-AL, O-PF, and O-WF groups but were reduced to lean levels in the O-E/Mx groups. These studies indicate that, unlike food restriction, the ephedrine-methylxanthine mixture prevents or arrests the development of the obesity in the fa/fa mutant by normalizing their energetic efficiency to that of the lean.
Liquid Crystalline Materials (2005)

Abstract Orientational and Positional Order in Fluids Thermotropic Liquid Crystals Polymorphism Synthesis Polymer Liquid Crystals Liquid Crystals in Biological Systems
Emission spectra of KrXeCl*, KrXeBr*, KrXeI*, ArKrF*, and ArKrCl* (1981)

Sensitized reactions of Xe and Kr with halogen donors in the presence of high buffer gas pressures of Kr and Ar, respectively, have led to the observation of five emission bands in the ultraviolet region of the spectrum. These broad structureless bands are assigned to the mixed rare gas–halide trimers KrXeCl, KrXeBr, KrXeI, ArKrF, and ArKrCl. Despite an extensive search, no emission corresponding to KrXeF could be found and this mixed trimer may be unstable because of interaction with a lower repulsive state. The positions and half-widths of the five emission bands are characterized, and the formation mechanism of the mixed trimers in these experiments is discussed.
Evaluation of Double Filtration Plasmapheresis, Thermofiltration, and Low–Density Lipoprotein Adsorptive Methods by Crossover Test in the Treatment of Familial Hypercholesterolemia Patients (1996)

A comparative assessment has been made regarding efficacy and safety of the double filtration plasmapheresis (DFPP), thermofiltration (TFPP), and low-density lipoprotein (LDL) adsorptive (PA) methods by making a crossover test on heterozygous familial hypercholesterolemia patients. Treatments by DFPP, TFPP (secondary membrane Evalux 5A), and PA (Liposorber LA-40) were carried out 5 times each, with a 2-week interval, in 5 patients with heterozygous familial hypercholesterolemia. The same plasma separator (Plasmacure PS-60, polysulfone) was used in all cases, and the volume of plasma processed was set at 4 L. High removal rates were obtained of total cholesterol, LDL cholesterol, triglycerides TG, and apolipoprotein B (apoB) by all three methods, and no differences were observed. Lipoprotein (a), apoA-2, apoC-3, fibrinogen, and immunoglobulin M (IgM) showed significantly high removal rates by the DFPP and TFPP methods compared with the PA method. The sieving coefficient of albumin and high-density lipoprotein (HDL) cholesterol at 2 and 4 L of plasma processed exhibited high permeabilities using all three methods. Supplementing albumin was not necessary. An increase of the transmembrane pressure was observed in 1 case treated by DFPP but was not observed when using the TFPP or PA method. No changes were observed in serum interleukin 1beta (IL-1beta) or tumor necrosis factor-alpha (TNF-alpha) before and after treatment by any of the three methods. No remarkable side effects were observed using either the DFPP or TFPP method. The DFPP and TFPP methods showed efficacy and safety that was not inferior to the PA method in conventional LDL apheresis, and the dead-end method of the filter operation without the discarding of plasma was shown to be possible.
Smart home services based on event matching (2013)

The smart home based on the Internet-of-Things (IoT) and other technologies provides people a living environment with security, convenience, comfort, environmental protection and intelligence. One of the key issues for the smart home service system is how to process real-time data from IoT layer rapidly and supply an initiative service with precision, individuation and intelligence. This paper proposes a smart home service framework based on event matching, and designs a hierarchical model for smart home services supporting real-time data awareness, data processing, event processing and service mapping. At the same time we improve the Rete algorithm to implement event engine and analyze the performance of the improved Rete algorithm. At last, an application is used to verify the feasibility and effectiveness of the smart home service based on event matching.
Lighting from thin (<1 mm) sheets of microcavity plasma arrays fabricated in Al/Al<sub>2</sub>O<sub>3</sub>/glass structures: planar, mercury-free lamps with radiating areas beyond 200 cm<sup>2</sup> (2007)

Flat lamps, having radiating areas as large as 15 × 15 cm2 and comprising arrays of Al/Al2O3 microcavity plasma devices, have been fabricated and characterized in the rare gases. Sealed arrays of devices with microcavities having diamond-shaped cross-sections yield lamps with an overall thickness of ∼800 µm (of which ∼500 µm is the quartz output window) and luminance and luminous efficacy values greater than 1600 cd m−2 and 10 lm W−1, respectively, are observed in preliminary experiments in which microplasmas in a Ne/20%Xe mixture illuminate a commercial green phosphor in a transmission arrangement with the ∼10 µm thick phosphor film situated immediately above the array. Efficacy values well in excess of 20 lm W−1 are expected when the array design and microcavity-phosphor geometry are optimized. Fully flexible arrays sealed in polymeric packaging have also been demonstrated, thereby providing access to new opportunities for lighting in which lightweight arrays are mounted onto curved surfaces.
Experiments of ana4 : An implementation of a 2.5 framework for deploying real multi-hop ad hoc and mesh networks (2005)

International audience
Enhancement of esterification conversion using pervaporation membrane reactor (2016)

In the present study, the esterification reaction of propionic acid with isobutyl alcohol to produce isobutyl propionate and water was studied. The performance of esterification reaction was compared by using the batch process and the pervaporation assisted hybrid process which performs the reaction and separation simultaneously. A polyvinyl alcohol-polyethersulphone (PVA-PES) hydrophilic polymeric membrane was used in the study to separate water and also to shift the equilibrium. The influence of process parameters such as catalyst loading, molar ratio of acid to alcohol, reaction temperature and ratio of membrane area to initial reaction volume (S/V) was studied. The results showed that the pervaporation assisted esterification process gave more conversion than the batch process of esterification. The membrane showed high selectivity to the removal of water in the propionic acid, isobutyl alcohol, isobutyl propionate and water mixture. Moreover, the conversion of propionic acid was enhanced by enhancing the catalyst amount, molar ratio of acid to alcohol, reaction temperature and S/V ratio.
Plasma Cell Survival Is Mediated by Synergistic Effects of Cytokines and Adhesion-Dependent Signals (2003)

Recent results suggest that plasma cell longevity is not an intrinsic capacity, but depends on yet unknown factors produced in their environment. In this study, we show that the cytokines IL-5, IL-6, TNF-alpha, and stromal cell-derived factor-1alpha as well as signaling via CD44 support the survival of isolated bone marrow plasma cells. The cytokines IL-7 and stem cell factor, crucially important for early B cell development, do not mediate plasma cell survival, indicating that plasma cells and early B cells have different survival requirements. As shown in IL-6-deficient mice, IL-6 is required for a normal induction, but not for the maintenance of plasma cell responses in vivo, indicating that the effects of individual survival factors are redundant. Optimal survival of isolated plasma cells requires stimulation by a combination of factors acting synergistically. These results strongly support the concept that plasma cell survival depends on niches in which a combination of specific signals, including IL-5, IL-6, stromal cell-derived factor-1alpha, TNF-alpha, and ligands for CD44, provides an environment required to mediate plasma cell longevity.
Enzymatic Synthesis of Caged NADP Cofactors:  Aqueous NADP Photorelease and Optical Properties (2000)

The synthesis of caged NADP analogues 18, 19, and 20 has been accomplished by utilizing the transglycosidase activity of solubilized NAD glycohydrolase (porcine brain) to incorporate caged nicotinamides 2, 3, and 4 into NADP. The synthesis of several nicotinamides modified at the carboxamide with o-nitrobenzyl photolabile groups is demonstrated as well as their potential for enzymatic transglycosidation. These results further demonstrate the feasibility of direct enzymatic transglycosidation of sterically hindered substrates into NAD(P), although high nicotinamide analogue water solubility was found to be a necessary trait for yield enhancement with certain analogues. Caged analogues were surveyed under aqueous conditions for net NADP photorelease, while the UV and fluorescent properties of both analogues and their photobyproducts were assessed for compatibility with systems that rely on optical monitoring of enzyme activity. A highly water-soluble alpha-methyl-o-nitrobenzyl group 8 was developed for the synthesis of 20 in order to enhance net NADP photorelease. Compound 20 demonstrated a high 75% net NADP photoreleased without substantial UV optical blackening or fluorescent byproducts. Analogues 18 and 19 were shown by ESI/MALDI-MS to photogenerate primarily adducts of NADP with deleterious UV and fluorescent properties. Our work stresses the superior release properties conferred by alpha-methyl substitution on aqueous carboxamide photorelease from o-nitrobenzyl compounds.
Using Sod On Highways (1945)

We build curbs and gutters for our city streets and use eaves troughs and spouting on our houses to dispose of runoff water. But what about the road ditches on our highways?
Optical gain equalisation with short period fiber gratings (1997)

Gain equalisation with a short period fiber grating per amplifier is successfully demonstrated on a 8/spl times/2.5 Gbit/s WDM transmission including 80 repeaters. The possible influence of the coherent Rayleigh noise is investigated for various repeater designs.
Polyoxometalates with Internal Cavities:  Redox Activity, Basicity, and Cation Encapsulation in [X<i><sup>n</sup></i><sup>+</sup>P<sub>5</sub>W<sub>30</sub>O<sub>110</sub>]<sup>(15</sup><sup>-</sup><i><sup>n</sup></i><sup>)</sup><sup>-</sup> Preyssler Complexes, with X = Na<sup>+</sup>, Ca<sup>2+</sup>, Y<sup>3+</sup>, La<sup>3+</sup>, Ce<sup>3+</sup>, and Th<sup>4+</sup> (2007)

The Preyssler anion, of general formula [Xn+P5W30O110](15-n)-, is the smallest polyoxometalate (POM) with an internal cavity allowing cation exchange with the solution. The Preyssler anion features a rich chemistry evidenced by its ability to accept electrons at low potentials, to selectively capture various metal cations, and to undergo acid-base reactions. A deep understanding of these topics is herein provided by means of DFT calculations on the title series of compounds. We evaluate the energetics of the release/encapsulation process for several Xn+ cations and identify the effect of the encapsulated ion on the properties of the Preyssler anion. We revisit the relationship between the internal cation charge and the electrochemical behavior of the POM. A linear dependence between the first one-electron reduction energies and the encapsulated Xn+ charge is found, with a slope of 48 mV per unit charge. The protonation also shifts the reduction potential to more positive values, but the effect is much larger. In connection to this, the last proton's pKa = 2 for the Na+ derivative was estimated to be in reasonable agreement with experiment. The electronic structure of lanthanide derivatives is more complex than conventional POM structures. The reduction energy for the CeIV-Preyssler + 1e- --> CeIII-Preyssler process was computed to be more exothermic than that of very oxidant species such as S2Mo18O624-.
Theory of current-driven instability experiments in magnetic Taylor-Couette flows (2007)

We consider the linear stability of dissipative magnetic Taylor-Couette flow with imposed toroidal magnetic fields. The inner and outer cylinders can be either insulating or conducting; the inner one rotates, the outer one is stationary. The magnetic Prandtl number can be as small as 10(-5) , approaching realistic liquid-metal values. The magnetic field destabilizes the flow, except for radial profiles of B(phi)(R) close to the current-free solution. The profile with B(in)=B(out) (the most uniform field) is considered in detail. For weak fields the Taylor-Couette flow is stabilized, until for moderately strong fields the m=1 azimuthal mode dramatically destabilizes the flow again so that a maximum value for the critical Reynolds number exists. For sufficiently strong fields (as measured by the Hartmann number) the toroidal field is always unstable, even for the nonrotating case with Re=0 . The electric currents needed to generate the required toroidal fields in laboratory experiments are a few kA if liquid sodium is used, somewhat more if gallium is used. Weaker currents are needed for wider gaps, so a wide-gap apparatus could succeed even with gallium. The critical Reynolds numbers are only somewhat larger than the nonmagnetic values; hence such experiments would work with only modest rotation rates.
Use of Respimat� Soft Mist? Inhaler in COPD patients (2006)

Events of the past decade have stimulated development of new drug formulations and delivery devices that have improved the efficiency, ease of use, and environmental impact of inhaled drug therapy. Respimat Soft Mist Inhaler is a novel, multidose, propellant-free, hand-held, liquid inhaler that represents a new category of inhaler devices. The aerosol cloud generated by Respimat contains a higher fraction of fine particles than most pressurized metered dose inhalers (pMDIs) and dry powder inhalers (DPIs), and the aerosol spray exits the inhaler more slowly and for a longer duration than with pMDIs. This translates into higher lung drug deposition and lower oropharyngeal deposition, making it possible to give lower nominal doses of delivered drugs without lowering efficacy. In clinical trials in patients with COPD, bronchodilator drugs delivered from Respimat were equally effective at half of the dose delivered from a pMDI. In one study of inhaler preference, Respimat was preferred over the pMDI by patients with COPD and other obstructive lung diseases. Respimat is a valuable addition to the range of inhaler devices available to the patient with COPD.
Increases and decreases in drug use attributed to housing status among street-involved youth in a Canadian setting (2014)

Perceived changes in drug use due to housing status were relatively common in this setting and were associated with being homeless and, among those who increased their drug use, engaging in risky income generation activities. These findings suggest that structural factors, particularly housing and economic opportunities, may be crucial interventions for reducing or limiting drug use among street-involved youth.
Development of an EMI shielding ferrite: a case study (1999)

Ni-Zn EMI shielding spinel ferrite of the composition Ni/sub 0.30/Zn/sub 0.60/M/sub 0.10/Fe/sub 2/O/sub 4/, where M=Cu, have been synthesized by the conventional ceramic route and the properties were tailored for its use in ribbon flat cables of digital equipments in the operating frequency range of 30-200 MHz. These highly dense soft ferrites were obtained by the incorporation of sintering aids such as Cu. The microstructure of the ferrite showed angular grains of size /spl sim/20 /spl mu/m and inter/intragranular porosity. The spinel ferrite was lossy in nature and had a Curie temperature of /spl sim/170/spl deg/C and possessed impedance of 23.3, 59.6 and 121.5 Ohms at 30, 100 and 200 MHz respectively.
ISOLATION AND CHARACTERISATION OF A CULM- SPECIFIC PROMOTER ELEMENT FROM SUGARCANE (2005)

Sugarcane (Saccharum spp) is an important crop worldwide and is cultivated for the high level of sucrose in its mature internodes. Because of the exhaustion of the genetic potential in the commercial sugarcane germplasm conventional breeding has not lately been able to enhance sucrose content. Currently there is a concerted effort to improve culm sucrose content by genetic engineering which will require appropriate transgenes and promoters. One of the major constraints to genetic engineering of sugarcane is the lack of stable promoters required to drive tissueor organ-specific expression of transgenes. Tissue and developmental stage specific promoters allow targeting of transgene activity and in doing so reduce the impact on non-target tissues. These promoters could also be advantageous to manipulate certain aspects of sucrose metabolism specifically in mature culm tissue. In addition, no promoters are currently freely available to the South African Sugar Industry for use in their transgenic program. The primary goal of this project was therefore to isolate a mature tissue-specific promoter for use in transgenic sugarcane plants. The approach followed was firstly, to identify an endogenous gene expressed in the desired pattern, and then to isolate the corresponding promoter from the sugarcane genome. cDNA macroarrays were initially used to identify differentially expressed sequences. The tissue specificity of potential clones was confirmed using RNA blot analysis. Two clones (c23-a and c22-a) were isolated and confirmed to be mature culm specific. Clone c22-a (putative dirigentlike protein) was selected for promoter isolation based on its culm tissue specific expression pattern and its proximity to the 5’ end of the gene. Furthermore, to confirm the activity of this promoter in the storage parenchyma cells, the exact cellular localisation of the transcript in the mature tissue was determined through in situ hybridisation. In situ hybridisation results confirmed the presence of the transcript in the parenchyma cells of mature culm tissue only. Moreover, the transcript is present in high concentrations in the parenchyma tissues surrounding the vascular bundles and parenchyma cells of the vascular complex. The selected dirigent-like gene was sequenced to allow the design of primers that could be used for the isolation of the corresponding promoter region using a long-range inverse PCR (LR-
Generations of Game Analytics, Achievements and High Scores (2009)

This paper poses the question, how has game recording evolved over the generations and how will it affect future generations of players and game developers who have access to the digital past? High scores have a history behind them and as generations of games have moved forward they begin to record much more than just scores. The present player generation can record complete replays of their entire gameplay performances and even play against other recorded player ghosts. As the future generations of gamers and developers take over they will have unprecedented access to the digital history archive as it becomes easier and easier to record and store the past. Deciding what to do with that past will be the next generation’s task as games move into the future.
Diffusion Samplers as an Inexpensive Approach to Monitoring VOCs in Ground Water (1997)

Abstract Diffusion samplers installed in observation wells were found to be capable of yielding polyethylene to transmit other volatile compounds, such as benzene and toluene, indicates that the samplers can be used for a variety of volatile organic compounds. In wells at the study area, the volatile organic compound concentrations in water samples obtained using the samplers without prior purging were similar to concentrations in water samples obtained from the respective wells using traditional purging and sampling approaches. The low cost associated with this approach makes it a viable option for monitoring large observation‐well networks for volatile organic compounds.
Expert System for Fault Diagnosis of Transformer (1997)

This paper presents hybrid expert system for diagnosis of electric power transformer faults. The expert system diagnose and detect faults in oil-filled power transformers based on dissolved gas analysis. As the preprocessing stage, fuzzy information theory is used to manage the uncertainty in transformer fault diagnosis using dissolved gas analysis. The Kohonen neural network takes the interim results by applying fuzzy informations theory as inputs, and performs the transformer fault diagnosis. The Proposed system tested gas records of power transformers from Korea Electric Power Corporation to verify the diagnosis performance of transformer faults.
DETERMINATION OF AN IMPROVED SIROLIMUS (RAPAMYCIN)-BASED REGIMEN FOR INDUCTION OF ALLOGRAFT TOLERANCE IN MICE TREATED WITH ANTILYMPHOCYTE SERUM AND DONOR-SPECIFIC BONE MARROW1 (1998)

A single dose of sirolimus (18-24 mg/kg) administered on day 7, within the context of an ALS/BM immunosuppressive regimen, reliably induces permanent skin allograft acceptance in this model. In vitro measures of immunocompetence demonstrated an early nonspecific suppression of the recipients immune status and later recovery of third-party immunoreactivity. In vivo testing indicates an operationally tolerant state that is donor-specific 90 days after treatment.
Glycolipid migration from the apical to the equatorial subdomains of the sperm head plasma membrane precedes the acrosome reaction Evidence for a primary capacitation event in boar spermatozoa (1995)

In order to extend the static information of immunolabelling sulphogalactolipids in fixed boar spermatozoa, a fluorescent sulphogalactolipid analogue, galactose(3-sulphate)-beta 1-1'[(N-lissamine rhodaminyl)-12-aminodode-canoyl]-sphingosine, was incorporated into plasma membranes of living spermatozoa and its lateral distribution over the sperm head was studied. The fluorescent lipid was enriched in the apical ridge subdomain of freshly ejaculated sperm cells. After sperm binding to the zona pellucida the lipid redistributed to the equatorial segment of the sperm surface. A similar shift occurred during capacitation in vitro with 2 mM CaCl2 or with 4% (w/v) bovine serum albumin. The desulphated derivative galactose-beta 1-1'[(N-lissamine rhodaminyl)-12-aminododecanoyl]-sphingosine was also incorporated into the plasma membrane of freshly ejaculated sperm cells and clearly stained the apical ridge subdomain and the (pre)-equatorial subdomains of the sperm heads. The desulphogalactolipid analogue showed a slightly faster migration to the equatorial segment of the sperm plasma membrane than did its sulphated counterpart. The measured fluorescence intensity distributions correlated linearly with the spatial probe distribution, which was checked by fluorescence lifetime imaging microscopy. The observed migration of the incorporated glycolipids precedes the acrosome reaction and is one of the underlying molecular events likely to be important in the process of sperm capacitation. The results of this study suggest that lipid phase segregation is an important driving force for the organization of the sperm head plasma membrane into subdomains.