gebhart/patrepeval huggingface dataset:
Long Stroke Ram-Style Tensioner Technology (2013)

Abstract The focus of this presentation will be to discuss and evaluate major concerns in the development of Long Stroke Ram-Style Tensioners, as an enabling technology to address the upcoming demands of the Offshore Industry as it pushes to drill and produce in ultra-deep water. The increasing demand on riser tensioners to accommodate higher riser loads with longer stroke capability in ultra-deep water is pushing technology beyond what has been currently developed in the industry. Introduction As Drilling and Production recovery for oil and gas expands into water depths in excess of 8,000ft, tensioner technology is being challenged to provide realistic and cost effective solutions. As riser tensioners increase in size and capacity to accommodate high riser loads, well bay configurations and tensioner interfaces have a significant impact on the design of the support vessel. Tensioner stroke lengths are increasing rapidly in response to larger vessel offsets, heave displacements and updated Regulatory requirements for survival conditions. These long stroke high capacity tensioners are influencing well bay design. Specifically, the stack up clearance between decks, number of risers, jumper hose layout, riser spacing, production tree clearance and motions, equipment maintenance and access. It takes an iterative design effort to integrate all of these elements into a cost effective workable solution. There are two major tensioner configurations used in the industry today; the ram or push up style and the rod in tension or pull up style. Both tensioner styles have various pros and cons inherent in each configuration. Numerous factors are considered when selecting a tensioner for a particular project or vessel type such as operator preference, load ring accessibility, well bay configuration, tensioner capacity, component serviceability and cost.
Position location of partial discharges in power transformers using fiber acoustic sensor arrays (2006)

A novel partial-discharge positioning system was demonstrated using an acoustic sensor array composed of four fiber acoustic sensors and a signal-processing unit. A hyperbolic position-fixing algorithm was employed to locate partial discharges. Convolution, correlation, and leading edge with finite impulse response filtering were used to determine time differences of arrival (TDOAs). Partial-discharge positioning was demonstrated in a 500-gallon tank. The positioning results showed that the correlation and leading edge methods are more robust and accurate in determining the TDOAs than the convolution method. A positioning accuracy of 3.0% was achieved using the leading edge method with a sensing range of 755 mm. These positioning results also indicated that the best sensor array layout is to spread the sensors in the tank in order to achieve high positioning accuracy.
Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS (2017)

Amyotrophic lateral sclerosis (ALS) is a synaptopathy accompanied by the presence of cytoplasmic aggregates containing TDP-43, an RNA-binding protein linked to ∼97% of ALS cases. Using a Drosophila model of ALS, we show that TDP-43 overexpression (OE) in motor neurons results in decreased expression of the Hsc70-4 chaperone at the neuromuscular junction (NMJ). Mechanistically, mutant TDP-43 sequesters hsc70-4 mRNA and impairs its translation. Expression of the Hsc70-4 ortholog, HSPA8, is also reduced in primary motor neurons and NMJs of mice expressing mutant TDP-43. Electrophysiology, imaging, and genetic interaction experiments reveal TDP-43-dependent defects in synaptic vesicle endocytosis. These deficits can be partially restored by OE of Hsc70-4, cysteine-string protein (Csp), or dynamin. This suggests that TDP-43 toxicity results in part from impaired activity of the synaptic CSP/Hsc70 chaperone complex impacting dynamin function. Finally, Hsc70-4/HSPA8 expression is also post-transcriptionally reduced in fly and human induced pluripotent stem cell (iPSC) C9orf72 models, suggesting a common disease pathomechanism.
Monographische Übersicht der Gattung <i>Leptodermis</i> (1922)

Bei der Bestiamung der von Dr
Subband coding algorithms for video applications: videophone to HDTV-conferencing (1991)

Various subband coding schemes are developed for high compression video coding applications. These schemes are based on two distinct interframe subband models. Both models are compared and show that they perform equally under certain conditions. The first model, which is relatively less complex but operates at full speed, was considered for video conferencing applications at lower rates. The second model, however, due to its generic structure which operates at a reduced speed, was found to be suitable for high quality video applications. As a result, a CCITT compatible video coding scheme for HDTV conferencing is developed. For the best performance, the higher frequency bands were coded with a combination of interframe differential pulse code modulation (DPCM) and direct PCM.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Subspace Estimation and Decomposition for Large Millimeter-Wave MIMO Systems (2016)

Channel estimation and precoding in hybrid analog-digital millimeter-wave (mmWave) MIMO systems is a fundamental problem that has yet to be addressed, before any of the promised gains can be harnessed. For that matter, we propose a method (based on the well-known Arnoldi iteration) exploiting channel reciprocity in TDD systems and the sparsity of the channel's eigenmodes, to estimate the right (resp. left) singular subspaces of the channel, at the BS (resp. MS). We first describe the algorithm in the context of conventional MIMO systems, and derive bounds on the estimation error in the presence of distortions at both BS and MS. We later identify obstacles that hinder the application of such an algorithm to the hybrid analog-digital architecture, and address them individually. In view of fulfilling the constraints imposed by the hybrid analog-digital architecture, we further propose an iterative algorithm for subspace decomposition, whereby the above estimated subspaces, are approximated by a cascade of analog and digital precoder/combiner. Finally, we evaluate the performance of our scheme against the perfect CSI, fully digital case (i.e., an equivalent conventional MIMO system), and conclude that similar performance can be achieved, especially at medium-to-high SNR (where the performance gap is less than 5%), however, with a drastically lower number of RF chains (~4 to 8 times less).
Follicular helper T cell signature in type 1 diabetes (2014)

The strong genetic association between particular HLA alleles and type 1 diabetes (T1D) indicates a key role for CD4+ T cells in disease; however, the differentiation state of the responsible T cells is unclear. T cell differentiation originally was considered a dichotomy between Th1 and Th2 cells, with Th1 cells deemed culpable for autoimmune islet destruction. Now, multiple additional T cell differentiation fates are recognized with distinct roles. Here, we used a transgenic mouse model of diabetes to probe the gene expression profile of islet-specific T cells by microarray and identified a clear follicular helper T (Tfh) cell differentiation signature. Introduction of T cells with a Tfh cell phenotype from diabetic animals efficiently transferred diabetes to recipient animals. Furthermore, memory T cells from patients with T1D expressed elevated levels of Tfh cell markers, including CXCR5, ICOS, PDCD1, BCL6, and IL21. Defects in the IL-2 pathway are associated with T1D, and IL-2 inhibits Tfh cell differentiation in mice. Consistent with these previous observations, we found that IL-2 inhibited human Tfh cell differentiation and identified a relationship between IL-2 sensitivity in T cells from patients with T1D and acquisition of a Tfh cell phenotype. Together, these findings identify a Tfh cell signature in autoimmune diabetes and suggest that this population could be used as a biomarker and potentially targeted for T1D interventions.
Identification of Glycoprotein 330 as an Endocytic Receptor for Apolipoprotein J/Clusterin (1995)

Glycoprotein 330 (gp330) is a member of a family of endocytic receptors related to the low density lipoprotein receptor. gp330 has previously been shown to bind a number of ligands in common with its family member, the low density lipoprotein receptor-related protein (LRP). To identify ligands specific for gp330 and relevant to its localization on epithelia such as in the mammary gland, gp330-Sepharose affinity chromatography was performed. As a result, a 70-kDa protein was selected from human milk and identified by protein sequencing to be apolipoprotein J/clusterin (apoJ). Solid-phase binding assays confirmed that gp330 bound to apoJ with high affinity (Kd = 14.2 nM). Similarly, gp330 bound to apoJ transferred to nitrocellulose after SDS-polyacrylamide gel electrophoresis. LRP, however, showed no binding to apoJ in either type of assay. The binding of gp330 to apoJ could be competitively inhibited with excess apoJ as well as with the gp330 ligands apolipoprotein E, lipoprotein lipase, and the receptor-associated protein, a 39-kDa protein that acts to antagonize binding of all known ligands for gp330 and LRP. Several cultured cell lines that express gp330 and ones that do not express the receptor were examined for their ability to bind and internalize 125I-apoJ. Only cells that expressed gp330 endocytosed and degraded radiolabeled apoJ. Furthermore, F9 cells treated with retinoic acid and dibutyryl cyclic AMP to increase expression levels of gp330 displayed an increased capacity to internalize and degrade apoJ. Cellular internalization and degradation of radiolabeled apoJ could be inhibited with unlabeled apoJ, receptor-associated protein, and gp330 antibodies. The results indicate that gp330 but not LRP can bind to apoJ in vitro and that gp330 expressed by cells can mediate apoJ endocytosis leading to lysosomal degradation.
Sustained Water Oxidation Photocatalysis by a Bioinspired Manganese Cluster (2008)

The generation game: A manganese–oxo complex with a cubic {Mn4O4}7+ core catalyzes the electrooxidation of water when suspended within the aqueous channels of a Nafion membrane (see picture). Illumination with visible light under an applied potential of 1.0 V (vs Ag/AgCl) generates current over one thousand turnovers. The catalytically active species arises from photolysis and subsequent dissociation of the manganese complex. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z801132_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Robust strategies for active vibration control of strain actuated plate like structures (1998)

The design of robust control strategies for the active vibration control of isotropic plates is presented. The models of the structures are developed using the Rayleigh-Ritz method. A technique for the optimal placement of piezoelectric actuators is developed using modal controllability and a genetic algorithm (GA) as the search engine. The model was used to design robust controllers (LQG and H∞) for a cantilever supported plate. The proposed controllers were then implemented with the measured results comparing favourably with those predicted from simulation.
Nitrification options for pig wastewater treatment (2004)

Abstract Nitrification is a necessary and often limiting process in animal waste treatment for removal of nitrogen as N 2 through biological nitrification/denitrification systems. We evaluated three technologies for enhancing nitrification of pig lagoon wastewater prior to denitrification: overland flow, trickling filter, and a bioreactor using nitrifying pellets. The overland flow system consisted of a 4 × 20‐m plot with 2% slope with a subsurface impermeable barrier receiving a total N loading rate of 64–99 kg N ha −1 day −1 . Total N removal efficiency ranged from 36 to 42%, and 7% of the total N application was recovered in the effluent as nitrate. The trickling filter consisted of a 1‐m 3 tank filled with marl gravel media which supported a nitrifying biofilm. Lagoon wastewater was applied as a fine spray on the surface at hydraulic loading rates of 684 litres m −3 day −1 and total N loading rates of 249 g m −3 day −1 . The media filter treatment transformed up to 57% of the inflow total N into nitrate when wastewater was supplemented with lime. The nitrifying pellets technology used acclimated nitrifying cells immobilised in 3–5 mm polymer pellets. Pig wastewater was treated in an aerated fluidised reactor unit with a 15% (w/v) pellet concentration. Nitrification efficiencies of more than 90% were obtained in continuous flow treatment using total N loading rates of 438 g N m −3 day −1 and hydraulic residence time of 12 h. Two conclusions are suggested from this research: (1) that substantial nitrification of pig lagoon wastewater can be attained particularly using aerobic treatments with enriched nitrifying populations, and (2) that large mass removal of N from pig wastewater may be possible by sequencing nitrification and denitrification unit processes.
Characteristics of an internally illuminated calibration sphere (1983)

Measurements of the spatial angular variability of an internally illuminated integrating sphere have been made in the interest of using such a sphere to calibrate instruments with large angular fields of view. Spatial uniformity across a 29.8-cm aperture was found to be 1.9% or better for full twelve-lamp illumination and 2.6% for one-lamp illumination. Angular uniformity from normal to ±40° was found to be 3% or better.
ContextSeer (2008)

The advent of media-sharing sites like Flickr has drastically increased the volume of community-contributed multimedia resources on the web. However, due to their magnitudes, these collections are increasingly difficult to understand, search and navigate. To tackle these issues, a novel search system, ContextSeer, is developed to improve search quality (by reranking) and recommend supplementary information (i.e., search-related tags and canonical images) by leveraging the rich context cues, including the visual content, high-level concept scores, time and location metadata. First, we propose an ordinal reranking algorithm to enhance the semantic coherence of text-based search result by mining contextual patterns in an unsupervised fashion. A novel feature selection method, wc-tf-idf is also developed to select informative context cues. Second, to represent the diversity of search result, we propose an efficient algorithm cannoG to select multiple canonical images without clustering. Finally, ContextSeer enhances the search experience by further recommending relevant tags. Besides being effective and unsupervised, the proposed methods are efficient and can be finished at query time, which is vital for practical online applications. To evaluate ContextSeer, we have collected 0.5 million consumer photos from Flickr and manually annotated a number of queries by pooling to form a new benchmark, Flickr550. Ordinal reranking achieves significant performance gains both in Flcikr550 and TRECVID search benchmarks. Through a subjective test, cannoG expresses its representativeness and excellence for recommending multiple canonical images.
Size-selective synthesis of [9]–[11] and [13]cycloparaphenylenes (2012)

The first size-selective synthesis of [9]–[11] and [13]cycloparaphenylenes (CPP) has been achieved by strategically utilizing cis-1,4-diphenylcyclohexane-1,4-diyl as the key terphenyl-convertible L-shaped unit. To access the designed triangular or rectangular macrocyclic precursors, we utilized palladium-catalysed C–B/C–Br cross-coupling (Suzuki–Miyaura coupling) and/or nickel-mediated C–Br/C–Br coupling. We also established step-economical routes to [14] and [16]CPP using nickel-mediated C–Br/C–Br coupling. The final aromatization steps toward CPPs were accomplished with NaHSO4. Thus, combined with our previous size-selective synthesis of [12] and [14]–[16]CPP, we completed our size-selective synthesis of [9]–[16]CPP. The successful size-selective syntheses of [n]CPPs speak well for the flexibility and reliability of our strategy using a cyclohexane ring.
Real-time continuous curvature path planning of UAVS in cluttered environments (2008)

This paper presents a method for curvature continuous (G <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> continuous) path generation for a UAV flying in a cluttered environment in real-time. First we generate a collision free path using a rapidly-exploring random tree (RRT). However a UAV cannot fly this path since it consists of piecewise linear segments. G <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> continuous path algorithm using cubic Bezier spiral curves is presented in this paper. Simulation results show the superiority of cubic Bezier spiral curves to Dubins path and C <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> continuous cubic Bezier curves.
Design of a Perfect Black Absorber at Visible Frequencies Using Plasmonic Metamaterials (2011)

The design and fabrication of a plasmonic black absorber with almost 100% absorbance spanning a broad range of frequencies from ultraviolet (UV) to the near infrared (NIR) is demonstrated. The perfect plasmonic absorber is achieved by a combination of a metal film with suitable metal/dielectric nanocomposites. Our fabrication technique is simple, versatile, cost-effective, and compatible with current industrial methods for solar absorber production.
Replication of Red Clover Necrotic Mosaic Virus RNA in Cowpea Protoplasts: RNA 1 Replicates Independently of RNA 2 (1987)

SUMMARY Inoculation of cowpea mesophyll protoplasts with unseparated RNA 1 and RNA 2 from red clover necrotic mosaic virus in the presence of polyethylene glycol resulted in virus RNA replication, the synthesis of virus capsid polypeptide and the formation of virus particles; 75 to 85% of the viable protoplasts became infected and the yield of virus particles or virus RNA after 72 h incubation corresponded to about 3 × 106 virus genomes per infected protoplast. In contrast, no replication could be detected when protoplasts were inoculated with RNA 2 alone. However, inoculation of protoplasts with RNA 1 alone resulted in its replication and the formation of virus particles, with a yield similar to that obtained after inoculation with both RNAs. Since infection of plants requires both RNA 1 and RNA 2 to be present, the demonstration of the independent replication of RNA 1 in single cells strengthens the hypothesis that RNA 2 plays a role in the cell-to-cell transmission of the virus.
Superluminal Phenomena and the Quantum Preferred Frame (2000)

Motivated by a number of recent experiments, we discuss in this paper a speculative but physically admissible form and solutions of effective Maxwell-like equations describing propagation of electromagnetic field in a medium which ``feels'' a quantum preferred frame.
Spatial Location of the Space Charge Effect in Individual Ion Clouds Using Monodisperse Dried Microparticulate Injection with a Twin Quadrupole Inductively Coupled Plasma Mass Spectrometer (1997)

Pulses of analyte and matrix ions from individual drops are measured simultaneously using a twin quadrupole inductively coupled plasma mass spectrometer (ICP-MS). The sample solution is introduced by monodisperse dried microparticulate injection (MDMI). At modest Pb concentrations (500 ppm), a shoulder on the leading edge of the Li(+) signal appears. At higher matrix concentrations (1000 to at least 1500 ppm), a dip in the leading edge of the Li(+) signal develops. These changes in the shapes of the Li(+) pulses are attributed to space charge effects in the extraction system and ion optics of the mass spectrometer. A qualitative depiction for this behavior is proposed, in which the Li(+) ions are deflected out of the preferred ion path and then refocused by the ion optics. Part of the Li(+) ion cloud is driven ahead of the Pb(+) cloud, and part is trapped behind the Pb(+) cloud. The result is a shoulder on the leading edge of the Li(+) signal. With the Pb matrix present, the shapes of the analyte ion pulses are sensitive to the voltages applied to the first two ion lenses, especially the extractor lens. This observation shows that the part of the matrix effect that occurs in the ion optics takes place mainly in the first two lenses.
Catalytic asymmetric construction of morpholines and piperazines by palladium-catalyzed tandem allylic substitution reactions (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic asymmetric construction of morpholines and piperazines by palladium-catalyzed tandem allylic substitution reactionsYasuhiro Uozumi, Asako Tanahashi, and Tamio HayashiCite this: J. Org. Chem. 1993, 58, 24, 6826–6832Publication Date (Print):November 1, 1993Publication History Published online1 May 2002Published inissue 1 November 1993https://pubs.acs.org/doi/10.1021/jo00076a052https://doi.org/10.1021/jo00076a052research-articleACS PublicationsRequest reuse permissionsArticle Views903Altmetric-Citations96LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A NEW METHOD FOR EVALUATION OF THICKNESS AND MONITORING ITS VARIATION OF MEDIUM- AND LOW-LOSS MATERIALS (2009)

In this research paper, we propose an amplitude-only method for unique thickness evaluation of medium-and low-loss materials. The method is based on using amplitude-only measurements at different frequencies to evaluate the unique thickness. Main advantages of the method are a) it eliminates the necessity of repetitive measurements of different-length materials to evaluate the unknown thickness of the same type material and b) it determines the thickness at any desired frequency in the band. Because the method uses amplitude-only measurements and enables the thickness evaluation at any frequency, it can be a good candidate for thickness evaluation of materials in industrial-based applications.