gebhart/patrepeval huggingface dataset:
Electron Beam Direct Writing Technology for 64-Mb DRAM LSIs (1990)

This paper describes the electron beam direct writing technology for 64-Mb DRAM LSIs including a resist process for 0.3-µm resolution, the prevention of the charging problem by a conducting polymer, and proximity effect correction by both the pattern classification method and the subsidiary exposure method. A large amount of pattern data is processed after dividing the whole chip data into peripheral circuits and 256-kb memory mats. An experimental 64-Mb DRAM LSI is fabricated by these technologies.
Effect of Temperature of Gauging Solution on Setting Characteristics and Moisture Ingress of Magnesium Oxychloride Cement – An Eco-Friendly Cement (2012)

Magnesium oxychloride cement (MOC, Magnesia / Sorel’s Cement), discovered by Sorel S.T. in 1867 and has versatile cementing characteristics. Investigation pertaining to the effect of temperature of gauging solution on setting characteristics and moisture ingress (steam test) of Magnesium oxychloride cement (MOC) has been observed by authors in this paper. The experimental works have been carried out on different dry-mix compositions 1 : 0, 1 : 1, 1 : 2 & 1 : 3 and on different temperatures 30 o C, 35 o C, 40 o C & 45 o C at 28 o Be density of gauging solution (g.s.). It has been recorded that initial and final setting time of cement blocks decreased with increasing temperature of gauging solution in the each dry-mix composition. The increasing trends of both setting time with increasing ratio of inert filler (dolomite) have also been noticed at a particular temperature. Results shown that both setting times of cement blocks are directly proportional to the ratio of inert filler in the dry-mix composition but inversely to temperature of gauging solution. The temperature of magnesium chloride solution (gauging solution) shown the great effect on the moisture ingress of MOC.
Dynamics and topology optimization of piezoelectric fans (2002)

Piezoelectric fans are very low power, small, very low noise, solid-state devices that have recently emerged as viable thermal management solutions for a variety of portable electronics applications including laptop computers, cellular phones and wearable computers. Piezoelectric fans utilize piezoceramic patches bonded onto thin, low frequency flexible blades to drive the fan at its resonance frequency. The resonating, low frequency blade creates a streaming airflow directed at key electronics components. The optimization of a piezoelectric fan with two symmetrically placed piezoelectric patches is investigated through an analytical Bernoulli-Euler model as well as a finite element (FE) model of the composite piezo-beam. The closed form analytical solution is used to demonstrate that different optimal piezoceramic-to-blade length ratios and piezoceramic-to-blade thickness ratios exist for maximizing the electromechanical coupling factor (EMCF), tip deflection and rotation. Such optimization procedures provide simple design guidelines for the development of very-low power, high flow rate piezoelectric fans.
The biosynthesis of Caryophyllaceae‐like cyclic peptides in <i>Saponaria vaccaria</i> L. from DNA‐encoded precursors (2011)

Cyclic peptides (CPs) are produced in a very wide range of taxa. Their biosynthesis generally involves either non-ribosomal peptide synthases or ribosome-dependent production of precursor peptides. Plants within the Caryophyllaceae and certain other families produce CPs which generally consist of 5-9 proteinogenic amino acids. The biological roles for these CPs in the plant are not very clear, but many of them have activity in mammalian systems. There is currently very little known about the biosynthesis of CPs in the Caryophyllaceae. A collection of expressed sequence tags from developing seeds of Saponaria vaccaria was investigated for information about CP biosynthesis. This revealed genes that appeared to encode CP precursors which are subsequently cyclized to mature CPs. This was tested and confirmed by the expression of a cDNA encoding a putative precursor of the CP segetalin A in transformed S. vaccaria roots. Similarly, extracts of developing S. vaccaria seeds were shown to catalyze the production of segetalin A from the same putative (synthetic) precursor. Moreover, the presence in S. vaccaria seeds of two segetalins, J [cyclo(FGTHGLPAP)] and K [cyclo(GRVKA)], which was predicted by sequence analysis, was confirmed by liquid chromatography/mass spectrometry. Sequence analysis also predicts the presence of similar CP precursor genes in Dianthus caryophyllus and Citrus spp. The data support the ribosome-dependent biosynthesis of Caryophyllaceae-like CPs in the Caryophyllaceae and Rutaceae.
Organic Microchemistry (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic MicrochemistryT. S. MaCite this: Anal. Chem. 1960, 32, 5, 80–87Publication Date (Print):April 1, 1960Publication History Published online12 July 2002Published inissue 1 April 1960https://pubs.acs.org/doi/10.1021/ac60161a611https://doi.org/10.1021/ac60161a611research-articleACS PublicationsRequest reuse permissionsArticle Views56Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Three‐dimensional fracture propagation under specified well‐bore pressure (1988)

Abstract Results are presented for three‐dimensional planar fracture propagation in the presence of variations in confining stress, reservoir properties and frac‐fluid viscosity when the well‐bore pressure is constant throughout the frac‐job. Solid rock deformation during the frac‐job is described by the dislocation method with singular integral equations, and the fluid flow in the fracture is represented by the finite element method. A convergence study is undertaken on the three‐dimensional numerical model, and good agreement is obtained with results from laboratory tests and from the simpler circular model.
BDNF AND NGF TREATMENT IN LESIONED RATS (1992)

Effects of chronic intraventricular administration of recombinant human brain-derived neurotrophic factor (rhBDNF) or recombinant human nerve growth factor (rhNGF) on presynaptic hippocampal cholinergic function in adult rats with partial fimbrial transections were measured. Partial fimbrial transections reduced synaptosomal high affinity choline uptake, choline acetyltransferase activity, and [3H] acetylcholine synthesis by approximately 50-75%. Chronic treatment with rhBDNF failed to attenuate these lesion-induced decreases. In contrast, chronic rhNGF treatment increased all three parameters by 50-90% compared to lesioned control values. Chronic treatment with rhBDNF or rhNGF attenuated weight gain of the animals. The findings failed to provide evidence for a prominent role of BDNF in the function of adult cholinergic neurons, however, they suggest an action on central neurons involved in the regulation of food intake.
Adducin Is an In Vivo Substrate for Protein Kinase C: Phosphorylation in the MARCKS-related Domain Inhibits Activity in Promoting Spectrin–Actin Complexes and Occurs in Many Cells, Including Dendritic Spines of Neurons (1998)

Adducin is a heteromeric protein with subunits containing a COOH-terminal myristoylated alanine-rich C kinase substrate (MARCKS)-related domain that caps and preferentially recruits spectrin to the fast-growing ends of actin filaments. The basic MARCKS-related domain, present in alpha, beta, and gamma adducin subunits, binds calmodulin and contains the major phosphorylation site for protein kinase C (PKC). This report presents the first evidence that phosphorylation of the MARCKS-related domain modifies in vitro and in vivo activities of adducin involving actin and spectrin, and we demonstrate that adducin is a prominent in vivo substrate for PKC or other phorbol 12-myristate 13-acetate (PMA)-activated kinases in multiple cell types, including neurons. PKC phosphorylation of native and recombinant adducin inhibited actin capping measured using pyrene-actin polymerization and abolished activity of adducin in recruiting spectrin to ends and sides of actin filaments. A polyclonal antibody specific to the phosphorylated state of the RTPS-serine, which is the major PKC phosphorylation site in the MARCKS-related domain, was used to evaluate phosphorylation of adducin in cells. Reactivity with phosphoadducin antibody in immunoblots increased twofold in rat hippocampal slices, eight- to ninefold in human embryonal kidney (HEK 293) cells, threefold in MDCK cells, and greater than 10-fold in human erythrocytes after treatments with PMA, but not with forskolin. Thus, the RTPS-serine of adducin is an in vivo phosphorylation site for PKC or other PMA-activated kinases but not for cAMP-dependent protein kinase in a variety of cell types. Physiological consequences of the two PKC phosphorylation sites in the MARCKS-related domain were investigated by stably transfecting MDCK cells with either wild-type or PKC-unphosphorylatable S716A/S726A mutant alpha adducin. The mutant alpha adducin was no longer concentrated at the cell membrane at sites of cell-cell contact, and instead it was distributed as a cytoplasmic punctate pattern. Moreover, the cells expressing the mutant alpha adducin exhibited increased levels of cytoplasmic spectrin, which was colocalized with the mutant alpha adducin in a punctate pattern. Immunofluorescence with the phosphoadducin-specific antibody revealed the RTPS-serine phosphorylation of adducin in postsynaptic areas in the developing rat hippocampus. High levels of the phosphoadducin were detected in the dendritic spines of cultured hippocampal neurons. Spectrin also was a component of dendritic spines, although at distinct sites from the ones containing phosphoadducin. These data demonstrate that adducin is a significant in vivo substrate for PKC or other PMA-activated kinases in a variety of cells, and that phosphorylation of adducin occurs in dendritic spines that are believed to respond to external signals by changes in morphology and reorganization of cytoskeletal structures.
Intraoperative gamma probe detection of insulinoma in an elderly patient with pancreatic cystic lesions (2002)

Insulinoma is a rare endocrine tumour in the elderly. We report the case of an 81-year-old woman suffering from grand mal seizures. Insulinoma was suspected because plasma glucose and insulin levels were 1.5 mmol/l and 80.4 pmol/l, respectively. A pancreatic computerized tomography (CT) scan, magnetic resonance imaging (MRI) and arteriography were normal but (111)In-DTPA-octreotide scintigraphy detected a hotspot in the pancreatic tail. Intraoperative pancreatic ultrasonography and palpation were non-contributory due to multiple pancreatic cysts and nodular lesions. However, a gamma-detecting probe localized a small tumour, labelled preoperatively with (111)In-DTPA-octreotide. Intraoperative insulin measurements in portal venous blood confirmed the successful removal of an insulinoma that was 6 mm in diameter histologically. Pancreatic cystic lesions increase with age and make the intraoperative localization of the insulinoma difficult. Intraoperative gamma probe detection of the tumour labelled with (111)In-DTPA-octreotide might therefore constitute a useful surgical tool.
A general-purpose hearing aid prescription, simulation and testing system (2003)

The authors describe a comprehensive, integrated, microcomputer-based facility for research on hearing aid fitting and for clinical use. The system first applies formal prescription rules to audiometric measures that have been obtained from an individual patient to predict which hearing aid amplification function is likely to provide the optimal benefit for a hearing-impaired listener. It then designs and implements a filter in a digital-signal processing (DSP) board that precisely implements the desired gain function. Speech intelligibility and listener preferences can then be measured to evaluate the prescribed hearing aid gain function, using efficient, computer-based testing procedures. The system requires an IBM/AT compatible microcomputer, an ARIEL DSP-16 board, filters and associated analog audio equipment, and a mouse.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
M-PAES: a memetic algorithm for multiobjective optimization (2002)

A memetic algorithm for tackling multiobjective optimization problems is presented. The algorithm employs the proven local search strategy used in the Pareto archived evolution strategy (PAES) and combines it with the use of a population and recombination. Verification of the new M-PAES (memetic PAES) algorithm is carried out by testing it on a set of multiobjective 0/1 knapsack problems. On each problem instance, a comparison is made between the new memetic algorithm, the (1+1)-PAES local searcher, and the strength Pareto evolutionary algorithm (SPEA) of E. Zitzler and L. Thiele (1998, 1999).
Internal Curing of Concrete Bridge Decks in Utah (2013)

The objectives of this research were (a) to monitor in situ bridge deck properties such as moisture and diffusivity for both conventional concrete and concrete containing prewetted lightweight fine aggregate, which is intended to provide internal curing; (b) to compare deck performance in terms of early-age cracking; and (c) to evaluate the compressive strength and chloride permeability of concrete mixtures in the laboratory using cylinders cast in the field at the time of deck construction. The research scope included four bridges—two constructed with conventional concrete and two containing prewetted lightweight fine aggregate—in northern Utah. Data from sensors embedded in the concrete decks indicated that the moisture content of the internally cured concrete was 2% to 3% higher at 28 days than the moisture content of the conventional concrete. Although the internally cured concrete had a higher moisture content, the electrical conductivity values were approximately the same for all decks after a few months; these values suggested that the two types of concrete had similar diffusivity. At 28 days, the average strength of the internally cured concrete was 1% higher than that of the conventional concrete, and the internally cured concrete passed between 2% and 30% less current during the rapid chloride permeability test than the conventional concrete. After 2 months, three to five cracks about 0.2 to 0.3 mm in width were found on each of the conventional concrete bridge decks, but no visible signs of cracking were found in the bridge decks with internal curing.
A novel high‐performance Fourier transform ion cyclotron resonance cell for improved biopolymer characterization (2000)

A new trapped ion cell design for use with Fourier transform ion cyclotron resonance mass spectrometry is described. The design employs 15 cylindrical ring electrodes to generate trapping potential wells and 32 separately assignable rod electrodes for excitation and detection. The rod electrodes are positioned internal to the ring electrodes and provide excitation fields that are thereby linearized along the magnetic field over the entire trapped ion volume. The new design also affords flexibility in the shaping of the trapping field using the 15 ring electrodes. Many different trapping well shapes can be generated by applying different voltages to the individual ring electrodes, ranging from quadratic to linearly ramped along the magnetic field axis, to a shape that is nearly flat over the entire trap volume, but rises very steeply near the ends of the trap. This feature should be useful for trapping larger ion populations and extension of the useful range of ion manipulation and dissociation experiments since the number of stages of ion manipulation or dissociation is limited in practice by the initial trapped ion population size. Predicted trapping well shapes for two different ring electrode configurations are presented, and these and several other possible configurations are discussed, as are the predicted excitation fields based on the use of rod electrodes internal to the trapping ring electrodes. Initial results are presented from an implementation of the design using a 3.5 T superconducting magnet. It was found that ions can be successfully trapped and detected with this cell design and that selected ion accumulation can be performed with the utilization of four rods for quadrupolar excitation. The initial results presented here illustrate the feasibility of this cell design and demonstrate differences in observed performance based upon different trapping well shapes. Copyright © 2000 John Wiley & Sons, Ltd.
Electrical characterisation of PZT on rapid thermally annealed ruthenium oxide electrodes (1995)

Abstract The ferroelectric and dielectric properties of sol gel thin film PZT are affected by the physical structure of the substrate electrodes. Ruthenium oxide electrodes were fabricated using sputter deposition and rapid thermal processing (RTP). Thin film PZT was deposited on these electrodes using sol gel deposition and RTP. The ruthenium oxide was fabricated with oriented and non-oriented structures. X-ray diffraction (XRD) was used to identify the structures and orientation of the ruthenium oxide and of the PZT films. The effect of the substrates on the ferroelectric and dielectric properties is presented. A PZT film processed with RTP of 650°C for 60s possessed a remanent polarisation of Pr>20 μC/cm2. A comparison of the electrical properties of PZT on noble metals (gold and platinum) and ruthenium oxide electrodes is discussed in terms of leakage current and fatigue. RTP PZT on RTP ruthenium oxide showed no fatigue of Pr and ετ for >1010 polarisation reversals.
Ten-Year Follow-Up Study for Safety of Adjuvant 65 Influenza Vaccine in Man (1973)

Clinical follow-up was made of more than 2000 persons who had received adjuvant 65 type influenza or aqueous type influenza vaccine or who had served as unvaccinated controls in studies in which vaccines were given up to 10 yr previously. No long-term effect was noted other than the occurrence in no more than 0.8% of persons observed of a persistent nodule that was difficult to palpate and that was no larger than a small pea. The rates for occurrence of nodules in vaccinated persons were not significantly greater than in the unvaccinated controls. There was no significant difference in the percentage of persons who died between the groups for respiratory disease, cardiovascular disease, cancer, or for miscellaneous cause (p > 0.15 for each category by Fisher's exact test). All evidence points to safety of the adjuvant type vaccine both on short- and long-term observation.
HMG‐CoA reductase inhibitors and P‐glycoprotein modulation (2001)

1. Five 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins), (e.g. atorvastatin, fluvastatin, lovastatin, pravastatin and simvastatin), were investigated for their ability to reverse P-glycoprotein (P-gp) mediated rhodamine 123 (R123) transport in a murine monocytic leukaemia cell line that over-expresses the multi-drug resistance protein 1a/b (mdr1a/1b). 2. P-gp modulation was studied by a fluorimetric assay and confocal microscopy by means of R123 efflux and uptake experiments, respectively. 3. Atorvastatin acid, methyl ester and lactone, lovastatin lactone and simvastatin lactone inhibited R123 transport in a concentration-dependent manner. Lovastatin acid, simvastatin acid, fluvastatin and pravastatin did not show a significant inhibition of the R123 transport in our cell system. Atorvastatin methyl ester and lactone showed the highest affinities for P-gp and results were comparable for both methods. 4. In conclusion, monitoring of R123 transport in living cells by confocal microscopy in addition to fluorimetric assay is a sensitive tool to study P-gp affinity in drug screening that is especially useful for early phases of drug development.
Depression symptom dimensions as predictors of antidepressant treatment outcome: replicable evidence for interest-activity symptoms (2011)

Loss of interest, diminished activity and inability to make decisions predict poor outcome of antidepressant treatment even after adjustment for overall depression severity and other clinical covariates. The prominence of such symptoms may require additional treatment strategies and should be accounted for in future investigations of antidepressant response.
English stress and rhythm (1998)

article Free Access Share on English stress and rhythm: a phonetics courseware Author: Cecilia Shu-huei Sun Department of English, National Kaohsiung Normal University Department of English, National Kaohsiung Normal UniversityView Profile Authors Info & Claims ACM SIGCUE OutlookVolume 26Issue 3July 1998 pp 8–15https://doi.org/10.1145/311110.311113Online:01 July 1998Publication History 0citation495DownloadsMetricsTotal Citations0Total Downloads495Last 12 Months0Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Gasoline-Alcohol Blends in Internal Combustion Engines (1938)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGasoline-Alcohol Blends in Internal Combustion EnginesL. C. Lichty and C. W. PhelpsCite this: Ind. Eng. Chem. 1938, 30, 2, 222–230Publication Date (Print):February 1, 1938Publication History Published online1 May 2002Published inissue 1 February 1938https://pubs.acs.org/doi/10.1021/ie50338a023https://doi.org/10.1021/ie50338a023research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts