gebhart/patrepeval huggingface dataset:
Aqueous phase hydrogenation of furfural to tetrahydrofurfuryl alcohol on alkaline earth metal modified Ni/Al<sub>2</sub>O<sub>3</sub> (2016)

Furfural was converted to tetrahydrofurfuryl alcohol with high yield in water on alkaline earth metal modified Ni/Al<sub>2</sub>O<sub>3</sub>.
Highly Potent and Selective Zwitterionic Agonists of the δ‐Opioid Receptor. Part 1. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Effect of Metal Coverage on the Performance of 0.6-eV InGaAs Monolithic Interconnected Modules (2003)

With the device performance of 0.6eV InGaAs monolithic interconnected modules (MIMs) reaching open circuit voltages of 400 mV/junction and achieving excellent quantum efficiency, the next step to improve performance focuses on controlling the parasitic optical absorption in these MIMs. With an integrated spectral control approach, the design of grid finger and interconnect metallization affects both the output power and the optical absorption of the MIM. The effect of metal coverage on the optical and electrical performance of MIMs processed in a multi‐wafer environment is presented.
Synthesis of 5-alkyl-4-oxazoleacetic acid derivatives with hypolipidemic activities. (1988)

A series of 2-aryl and 2-alkyl derivatives of 5-alkyl-4-oxazoleacetic acids was synthesized and tested for hypolipidemic activity. Among them, 5-isopropyl-2-(4-fluorophenyl)-4-oxazoleacetates exhibited potent activities, being more active than clofibrate [ethyl 2-(4-chlorophenoxy) isobutvrate].
10-Hydroxy-3,4-dihydroacridine-1,9(2H,10H)-diones, a new group of malaricidal and coccidiostatic compounds. (1980)

2-Nitrobenzaldehydes and 1,3-cyclohexanediones condense in a mixture of hydrochloric acid and glacial acetic acid to 10-hydroxy-3,4-dihydroacridine-1,9(2H,10H)-diones. Many compounds of this group reveal a pronounced coccidiostatic and malaricidal effect in vivo even against drug-resistant malaria parasites. Synthesis and chemotherapeutic results as well as structure-activity relationships are described.
Changing The Channel (2014)

RETURN TO ISSUEPREVNewsNEXTChanging The ChannelView Author Information C&EN BostonCite this: Chem. Eng. News 2014, 92, 12, 10–14Publication Date (Print):March 24, 2014Publication History Published online31 March 2015Published inissue 24 March 2014https://pubs.acs.org/doi/10.1021/cen-09212-coverhttps://doi.org/10.1021/cen-09212-covernewsACS PublicationsCopyright © 2014 Chemical & Engineering NewsArticle Views17Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Neurophysiology Get e-Alerts
Establishment of transgene-free induced pluripotent stem cells reprogrammed from human stem cells of apical papilla for neural differentiation (2012)

TF-SCAP iPSCs reprogrammed from SCAP can be generated and they may be a good cell source for neurogenesis.
Resonant Cross-Commutated Dc-Dc Regulators with Omni-Coupled Inductors (2018)

The switching noise in a hard-switched point-of-load (POL) converter may result in false turn on, electromagnetic interference issues, or even device breakdown. A resonant cross-commutated buck (rccBuck) converter operates with low noise since all MOSFETs are turned on with zero voltage within a wide load range. A state-space model was developed to calculate the voltage gain, voltage stresses, and current stresses. Design guidelines for the rccBuck converter operating at continuous voltage mode or discontinuous voltage mode are provided. The design methodology of a one-turn inductor with significant ac and dc fluxes is given. Four fabricated one-turn inductors achieved 2.1% higher efficiency and 50% smaller total magnetic volume than the commercial inductors in the same rccBuck converter. The Omni-coupled inductors (OCI), composed of a twisted E-E core and PCB windings, further improve power density and efficiency. The core loss and inductances were modeled from a complex reluctance network. According to the loss-volume Pareto fronts, the total inductor loss was minimized within a smaller volume than that of discrete inductors. The expectations were validated by an OCI-based rccBuck converter switched at 2 MHz with 12 V input, 3.3 V at 20 A output, and peak efficiency of 96.2%. The small-signal model with a good accuracy up to half switching frequency was developed based on the averaged equivalent circuit. The transient performance of an rccBuck regulator is comparable to that of a second-order buck regulator with the same switching frequency, output capacitance, and closed-loop bandwidth.
Use of carbon dioxide stripping for struvite crystallization to save caustic dosage: performance at pilotscale operationPaper submitted to the Journal of Environmental Engineering and Science. (2010)

The feasibility of stripping CO 2 from anaerobic digester centrate (generated in a sludge dewatering process) to raise pH, and therefore reduce the cost of caustic chemical(s) dosage for similar operation in a struvite-recovery system, was investigated. A cascade CO 2 stripper was installed in a pilot-scale, struvite-recovery reactor system at the Lulu Island Wastewater Treatment Plant, Richmond, British Columbia, Canada, as a replacement of part of (about 1/3) the reactor downpipe. Centrate was used as the process feed. Both the influent and the effluent from the struvite reactor were analyzed for pH, temperature (°C), and concentrations of Mg, NH 4 -N, and PO 4 -P. Results indicated that, by adding the CO 2 stripper, caustic chemical savings was as much as 46%–65%. Moreover, because of the capability of the stripper in providing a more gradual pH increase, fewer fine solids were produced in the reactor than when caustic solution was used to raise the pH of the reactor.
Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells (2009)

The ability to target methylation to specific genomic sites would further the study of DNA methylation's biological role and potentially offer a tool for silencing gene expression and for treating diseases involving abnormal hypomethylation. The end-to-end fusion of DNA methyltransferases to zinc fingers has been shown to bias methylation to desired regions. However, the strategy is inherently limited because the methyltransferase domain remains active regardless of whether the zinc finger domain is bound at its cognate site and can methylate non-target sites. We demonstrate an alternative strategy in which fragments of a DNA methyltransferase, compromised in their ability to methylate DNA, are fused to two zinc fingers designed to bind 9 bp sites flanking a methylation target site. Using the naturally heterodimeric DNA methyltransferase M.EcoHK31I, which methylates the inner cytosine of 5'-YGGCCR-3', we demonstrate that this strategy can yield a methyltransferase capable of significant levels of methylation at the target site with undetectable levels of methylation at non-target sites in Escherichia coli. However, some non-target methylation could be detected at higher expression levels of the zinc finger methyltransferase indicating that further improvements will be necessary to attain the desired exclusive target specificity.
Acoustic Emissions as a Tool for Hydraulic Fracture Location: Experience at the Fenton Hill Hot Dry Rock Site (1982)

Abstract Microearthquakes with magnitudes between −6 and −2 have been observed in three successive massive injections of water at the hot dry rock geothermal energy development project's demonstration site at Fenton Hill, NM. The injections were part of a program to increase the heat transfer area of hydraulic fractures and to decrease the flow-through impedance between wells in the energy extraction system under construction. The microearthquakes were used in mapping the location of the extended hydraulic fractures. The large shear- to compressional-wave-amplitude ratio observed in the signals suggests that the microearthquakes result from shear failure, probably on preexisting planes of weakness that intersect or make up the main hydraulic system. Failure resulting from increased pore pressure is a likely cause for the microearthquakes. Knowledge of the failure criterion for the reservoir rocks permits calculation of the pore pressure increases necessary for failure. At Fenton Hill, it appears that pressures 2 Pa (0.00029 psi) above hydrostatic are necessary. For this hypothesis of microearthquake occurrence to hold, the effective reservoir permeability must be four orders of magnitude above that for the bulk rock, as would be the case if there were permeable joints or fractures in the reservoir before hydraulic stimulation.
Effects of exogenous ubiquitin in a polytrauma model with blunt chest trauma* (2012)

Administration of exogenous ubiquitin modulates the local inflammatory response, improves resuscitation, reduces fluid shifts into tissues, and preserves arterial oxygenation after blunt polytrauma with lung injury. This study further supports the notion that ubiquitin is a promising protein therapeutic and implies CXC chemokine receptor 4 as a drug target after polytrauma.
Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes (1993)

In the present study, we investigated the mechanisms that regulate apolipoprotein B-100 (apoB) secretion in response to the change of intracellular cholesteryl ester contents by adding low density lipoprotein (LDL) and an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase (pravastatin) in rabbit hepatocyte culture system. LDL caused a significant dose-dependent increase in apoB secretion. On the other hand, the addition of pravastatin decreased apoB secretion significantly. LDL caused a dose-dependent increase in cellular cholesteryl ester, while cellular cholesteryl ester was decreased by pravastatin significantly. Therefore, these results indicate that the change of apoB secretion was in parallel with the change of cellular cholesteryl ester contents. Cellular contents of free cholesterol, triglyceride, and phospholipid did not change. To investigate intracellular degradation of apoB prior to secretion, pulse-chase experiments were performed. It was shown that the addition of pravastatin accelerated intracellular degradation of apoB, while LDL slowed the apoB intracellular degradation rate. We also investigated whether the change of cellular cholesteryl ester could affect the apoB mRNA level. Northern blot analysis and solution hybridization RNase protection assay demonstrated that neither LDL nor pravastatin caused a significant change in cellular apoB mRNA level. We conclude that intracellular cholesteryl ester contents play a critical role in apoB secretion, and the intracellular apoB degradation rate could be the main mechanism that regulates apoB secretion in response to the change of intracellular cholesteryl ester level.
Retinoids and cancer (1986)

Conference Article| October 01 1986 Retinoids and cancer R. MARIAN HICKS; R. MARIAN HICKS 1School of Pathology, Middlesex Hospital Medical School, Riding House Street, London W1P 7LD, U.K. Search for other works by this author on: This Site PubMed Google Scholar JONATHAN TURTON JONATHAN TURTON 1School of Pathology, Middlesex Hospital Medical School, Riding House Street, London W1P 7LD, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1986) 14 (5): 939–942. https://doi.org/10.1042/bst0140939 Article history Received: April 29 1986 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation R. MARIAN HICKS, JONATHAN TURTON; Retinoids and cancer. Biochem Soc Trans 1 October 1986; 14 (5): 939–942. doi: https://doi.org/10.1042/bst0140939 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: BBN, N-butyl-N-(4-hydroxybutyl)nitrosamine, HPR, N-(4-hydroxyphenyl)retinamide, 13-NER, 13-cis-N-ethylretinamide, NSAIDs, non-steroidal anti-inflammatory drugs This content is only available as a PDF. © 1986 Biochemical Society1986 Article PDF first page preview Close Modal You do not currently have access to this content.
A Machine Learning Approach to Predict Gas Oil Ratio Based on Advanced Mud Gas Data (2019)

Abstract Mud gas data from drilling operations provide the very first indication of the presence of hydrocarbons in the reservoir. It has been a dream for decades in the oil industry to predict reservoir gas and oil properties from mud gas data, because it would provide knowledge of the reservoir fluid properties in an early stage, continuously for all reservoir zones, and at low costs. Previous efforts reported in the literature did not lead to a reliable method for quantitative prediction of the reservoir fluid properties from mud gas data. In this paper, we propose a novel approach based on machine learning which enables us to predict gas oil ratio (GOR) from advanced mud gas (AMG) data. The current work is based on a previous successful pilot in unconventional (shale) reservoirs. Our aim is to extend the results of the pilot study to conventional reservoirs. In general, prediction of reservoir fluid properties is more challenging for conventional reservoirs than for unconventional reservoirs, due to the complexity of petroleum systems in conventional reservoirs. Instead of building a model directly from AMG data, we trained a machine learning model using a well-established reservoir fluid database with more than 2000 PVT samples. After thorough investigation of compositional similarity between PVT samples and AMG data, we applied the model developed from PVT samples to AMG data. The predicted GORs from AMG data were compared with GOR measurements from corresponding PVT samples to assess the accuracy of the GOR predictions. The results from 22 wells with both AMG data and corresponding PVT samples show large agreement between prediction vs. measurement. The accuracy of the predictive model is much higher than previous results reported in the literature. In addition, a Quality Check (QC) metric was developed to efficiently flag low-quality AMG data. The QC metric is vital to give confidence level for GOR prediction based on AMG data when PVT samples are not available. The study confirms that AMG data can be used as a new data source to quantitatively predict continuous reservoir fluid properties in the drilling phase. The method can be used to optimize wireline operations and for some cases, it provides a unique opportunity to acquire reservoir fluid data when conventional fluid sampling or use of wireline tools is not possible. After high-quality PVT data becomes available in the wireline logging phase, the continuous GOR prediction can be further improved and used to determine reservoir fluid gradient and reservoir compartmentalization.
Performance evaluation of a high-speed jetting dispenser actuated by a ring-type piezostack (2009)

This article presents performance results of a new type of jetting dispenser driven by a ring-type piezostack actuator. The proposed dispenser can provide a very small dispensing dot size of a low viscous adhesive, from 50 to 500 cp, at a high dispensing flowrate in semiconductor packaging processes. After describing the mechanism and operational principle of the dispenser, a mathematical model of the system is derived by considering behaviours of the piezostack, the actuating spring, the dispensing needle, and the adhesive fluid dynamics. In the modelling, a lumped parameter method is applied to model the adhesive, for which the rheological property is approximately expressed by the Bingham model. The governing equation of the dispensing system is then derived by integrating the structural model with the fluid model. Based on the proposed model, the jetting dispenser is designed and manufactured. The dispensing performances such as dot size and dispensing flowrate are then evaluated from both the proposed model and experimental investigation. Subsequently, a method to control the dispensing flowrate is proposed and applied to the proposed dispenser to achieve the desired dispensing amount.
Task Lineages: Dialog State Tracking for Flexible Interaction (2016)

We consider the gap between user demands for seamless handling of complex interactions, and recent advances in dialog state tracking technologies. We propose a new statistical approach, Task Lineage-based Dialog State Tracking (TL-DST), aimed at seamlessly orchestrating multiple tasks with complex goals across multiple domains in continuous interaction. TL-DST consists of three components: (1) task frame parsing, (2) context fetching and (3) task state update (for which TL-DST takes advantage of previous work in dialog state tracking). There is at present very little publicly available multi-task, complex goal dialog data; however, as a proof of concept, we applied TL-DST to the Dialog State Tracking Challenge (DSTC) 2 data, resulting in state-of-the-art performance. TL-DST also outperforms the DSTC baseline tracker on a set of pseudo-real datasets involving multiple tasks with complex goals which were synthesized using DSTC3 data.
The first example of transition-metal-catalyzed addition of aromatic thiols to acetylenes (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe first example of transition-metal-catalyzed addition of aromatic thiols to acetylenesHitoshi Kuniyasu, Akiya Ogawa, Kenichiro Sato, Ilhyong Ryu, Nobuaki Kambe, and Noboru SonodaCite this: J. Am. Chem. Soc. 1992, 114, 14, 5902–5903Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July 1992https://pubs.acs.org/doi/10.1021/ja00040a087https://doi.org/10.1021/ja00040a087research-articleACS PublicationsRequest reuse permissionsArticle Views1422Altmetric-Citations216LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A neural fuzzy resource manager for hierarchical cellular systems supporting multimedia services (2003)

Using intelligent techniques to perform radio resource management is an effective method. The paper proposes neural fuzzy control for radio resource management in hierarchical cellular systems supporting multimedia services. A neural fuzzy resource manager (NFRM) is designed, which mainly contains a neural fuzzy channel allocation processor (NFCAP). The NFCAP has a two-layer architecture: a fuzzy cell selector (FCS) in the first layer and a neural fuzzy call-admission and rate controller (NFCRC) in the second layer. The FCS chooses not only the handoff failure probabilities and the resource availabilities in both microcell and macrocell, but also the user mobility, as input linguistic variables. The NFCRC takes the handoff failure probability and the resource availability of the selected cell as input variables to perform call admission control and rate control for the call. Simulation results show that the NFRM can always guarantee the quality of service (QoS) requirement for handoff failure probability for all traffic loads. Also, the NFRM improves the system utilization by 31.1% while increasing the handoff rate by 2% over the overflow channel allocation (OCA) scheme; it enhances the system utilization by 6.3% and 1.4%, and still reduces the handoff rate by 14.9% and 6.8%, as compared to the combined channel allocation (CCA) and fuzzy channel allocation control (FCAC) schemes, respectively, under a predefined QoS constraint.
The N-glycan processing enzymes α-mannosidase and β-D-N-acetylhexosaminidase are involved in ripening-associated softening in the non-climacteric fruits of capsicum (2010)

Excessive softening of fruits during the ripening process leads to deterioration. This is of significant global importance as softening-mediated deterioration leads to huge postharvest losses. N-glycan processing enzymes are reported to play an important role during climacteric fruit softening: however, to date these enzymes have not been characterized in non-climacteric fruit. Two ripening-specific N-glycan processing enzymes, α-mannosidase (α-Man) and β-D-N-acetylhexosaminidase (β-Hex), have been identified and targeted to enhance the shelf life in non-climacteric fruits such as capsicum (Capsicum annuum). The purification, cloning, and functional characterization of α-Man and β-Hex from capsicum, which belong to glycosyl hydrolase (GH) families 38 and 20, respectively, are described here. α-Man and β-Hex are cell wall glycoproteins that are able to cleave terminal α-mannose and β-D-N-acetylglucosamine residues of N-glycans, respectively. α-Man and β-Hex transcripts as well as enzyme activity increase with the ripening and/or softening of capsicum. The function of α-Man and β-Hex in capsicum softening is investigated through RNA interference (RNAi) in fruits. α-Man and β-Hex RNAi fruits were approximately two times firmer compared with the control and fruit deterioration was delayed by approximately 7 d. It is shown that silencing of α-Man and β-Hex enhances fruit shelf life due to the reduced degradation of N-glycoproteins which resulted in delayed softening. Altogether, the results provide evidence for the involvement of N-glycan processing in non-climacteric fruit softening. In conclusion, genetic engineering of N-glycan processing can be a common strategy in both climacteric and non-climacteric species to reduce the post-harvest crop losses.
B7x and myeloid-derived suppressor cells in the tumor microenvironment (2013)

A new study demonstrates the tumorigenic functions of B7x and reveals a link between B7x and myeloid-derived suppressor cells (MDSCs) within the tumor microenvironment. We propose that the binding of B7x to a hitherto unidentified receptor on MDSCs may stimulate their proliferation and/or immunosuppressive functions, hence promoting tumor growth.