gebhart/patrepeval huggingface dataset:
Translational Control Mediated by UA-Rich Sequences (1990)

Several messenger RNAs coding for cytokines, growth factors or oncoproteins contain a conserved UA-rich sequence in their 3' untranslated regions. This sequence, which is composed of several interspersed repeats of the octanucleotide UUAUUUAU, is a key element in the posttranscriptional regulation of these mRNAs. Previously shown to be involved in mRNA destabilization, these UA-rich elements can also strongly influence mRNA translation. A translation inhibition mediated by these sequences has indeed been observed in vitro as well as in frog oocyte or in somatic cells.
Cubic Silicon Carbide (3C-SiC): Structure and Properties of Single Crystals Grown by Thermal Decomposition of Methyl Trichlorosilane in Hydrogen (1997)

This overview, based on earlier published papers, concerns the growth and some properties of single and polycrystalline cubic silicon carbide (3C-SiC) prepared by thermal decomposition of methyl trichlorosilane in hydrogen on resistively heated graphite substrates in a temperature range of 1500 to 2100 K. The morphology of faceted crystals and their specific twin structure, as well as the effects of crystallographic polarity of the 3C-SiC structure (sphalerite type) on impurity segregation and etching are considered in some detail.
Less harmful acidic degradation of poly(lactic-co-glycolic acid) bone tissue engineering scaffolds through titania nanoparticle addition (2006)

In the last 10 years, biodegradable aliphatic polyesters, such as poly(lactic-co-glycolic acid) (PLGA), have attracted increasing attention for their use as scaffold materials in bone tissue engineering because their degradation products can be removed by natural metabolic pathways. However, one main concern with the use of these specific polymers is that their degradation products reduce local pH, which in turn induces an inflammatory reaction and damages bone cell health at the implant site. Thus, the objective of the present in vitro study was to investigate the degradation behavior of PLGA when added with dispersed titania nanoparticles. The results of this study provided the first evidence that the increased dispersion of nanophase titania in PLGA decreased the harmful change in pH normal for PLGA degradation. Moreover, previous studies have demonstrated that the increased dispersion of titania nanoparticles into PLGA significantly improved osteoblast (bone-forming cell) functions (such as adhesion, collagen synthesis, alkaline phosphatase activity, and calcium-containing minerals deposition). In this manner, nanophase titania-PLGA composites may be promising scaffold materials for more effective orthopedic tissue engineering applications.
Contribution of AMPA, NMDA, and GABA<sub>A</sub>Receptors to Temporal Pattern of Postsynaptic Responses in the Inferior Colliculus of the Rat (2004)

The central nucleus of the inferior colliculus (ICC) is a major site of synaptic interaction in the central auditory system. To understand how ICC neurons integrate excitatory and inhibitory inputs for processing temporal information, we examined postsynaptic responses of ICC neurons to repetitive stimulation of the lateral lemniscus at 10-100 Hz in rat brain slices. The excitatory synaptic currents mediated by AMPA and NMDA receptors and the inhibitory current mediated by GABA(A) receptors were pharmacologically isolated and recorded by whole-cell patch-clamp techniques. The response kinetics of AMPA receptor-mediated EPSCs and GABA(A) receptor-mediated IPSCs were similar and much faster than those of NMDA receptor-mediated EPSCs. AMPA EPSCs could follow each pulse of stimulation at a rate of 10-100 Hz but showed response depression during the course of repetitive stimulation. GABA(A) IPSCs could also follow stimulus pulses over this frequency range but showed depression at low rates and facilitation at higher rates. NMDA EPSCs showed facilitation and temporal summation in response to repetitive stimulation, which was most pronounced at higher rates of stimulation. GABA(A) inhibition suppressed activation of NMDA receptors and reduced both the degree of AMPA EPSC depression and the extent of temporal summation of NMDA EPSCs. The results indicate that GABA(A) receptor-mediated inhibition plays a crucial role in maintaining the balance of excitation and inhibition and in allowing ICC neurons to process temporal information more precisely.
Deep Learning-Based Object Classification and Position Estimation Pipeline for Potential Use in Robotized Pick-and-Place Operations (2020)

Accurate object classification and position estimation is a crucial part of executing autonomous pick-and-place operations by a robot and can be realized using RGB-D sensors becoming increasingly available for use in industrial applications. In this paper, we present a novel unified framework for object detection and classification using a combination of point cloud processing and deep learning techniques. The proposed model uses two streams that recognize objects on RGB and depth data separately and combines the two in later stages to classify objects. Experimental evaluation of the proposed model including classification accuracy compared with previous works demonstrates its effectiveness and efficiency, making the model suitable for real-time applications. In particular, the experiments performed on the Washington RGB-D object dataset show that the proposed framework has 97.5% and 95% fewer parameters compared to the previous state-of-the-art multimodel neural networks Fus-CNN, CNN Features and VGG3D, respectively, with the cost of approximately 5% drop in classification accuracy. Moreover, the inference of the proposed framework takes 66.11%, 32.65%, and 28.77% less time on GPU and 86.91%, 51.12%, and 50.15% less time on CPU in comparison to VGG3D, Fus-CNN, and CNN Features. The potential applicability of the developed object classification and position estimation framework was then demonstrated on an experimental robot-manipulation setup realizing a simplified object pick-and-place scenario. In approximately 95% of test trials, the system was able to accurately position the robot over the detected objects of interest in an automatic mode, ensuring stable cyclic execution with no time delays.
Closed-loop shape control of a Haptic Jamming deformable surface (2016)

A Haptic Jamming tactile display, consisting of an array of thin particle jamming cells, can change its shape and mechanical properties simultaneously through a combination of vacuuming individual cells, pressurizing the air chamber beneath the surface, and pinning the nodes between the cells at various heights. In previous particle jamming devices for haptics and soft robotics, shape has typically been commanded open-loop or manipulated directly by a human user. A new algorithm was designed for the three types of actuation inputs for a Haptic Jamming surface, using the depth map provided by an RGB-D sensor as shape feedback for closed-loop control to match a desired surface input. To test the closed-loop control accuracy of the system, a mass-spring model of the Haptic Jamming device generated three unique surface shapes as desired inputs into the controller with a mean height range of 25.1 mm. The average correlation coefficient between the desired input shape and the experimental output generated by the controller on the actual device across four trials for each shape was 0.88, with an average height error of 2.7 mm. When the desired input surface is generated from a 3D model of an object that a Haptic Jamming surface cannot necessarily re-create, the difference between the input and the output increases substantially. However, simulation of a larger array suggests that a Haptic Jamming surface can provide a compelling match for these more complicated shapes.
Carob-Seed Gum (1930)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarob-Seed GumRalph HartCite this: Ind. Eng. Chem. Anal. Ed. 1930, 2, 3, 329–331Publication Date (Print):July 1, 1930Publication History Published online1 May 2002Published inissue 1 July 1930https://pubs.acs.org/doi/10.1021/ac50071a050https://doi.org/10.1021/ac50071a050research-articleACS PublicationsRequest reuse permissionsArticle Views90Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Principles of design of architectural coatings (1983)

A survey is presented of the essential design considerations involved in the development of architectural thin film coatings. The report is divided into two parts: the first deals with design factors that influence the thermal performance of windows; the second deals with questions of aesthetics, especially color. A brief discussion is included of heat transfer analysis as it applies to glazings, along with an attachment of some sample graphs of heat transfer properties and their relationship to the optical properties of coated glass. Also included is an overview, with computed examples, of the various coating design types that appear to be viable at the current stage of development in this field of thin films technology.
Bioactive Polyacetylenes from<i>Bidens pilosa</i> (1996)

From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines in culture.
Long-wavelength optical coherence tomography at 17 μm for enhanced imaging depth (2008)

Multiple scattering in a sample presents a significant limitation to achieve meaningful structural information at deeper penetration depths in optical coherence tomography (OCT). Previous studies suggest that the spectral region around 1.7 microm may exhibit reduced scattering coefficients in biological tissues compared to the widely used wavelengths around 1.3 mum. To investigate this long-wavelength region, we developed a wavelength-swept laser at 1.7 microm wavelength and conducted OCT or optical frequency domain imaging (OFDI) for the first time in this spectral range. The constructed laser is capable of providing a wide tuning range from 1.59 to 1.75 microm over 160 nm. When the laser was operated with a reduced tuning range over 95 nm at a repetition rate of 10.9 kHz and an average output power of 12.3 mW, the OFDI imaging system exhibited a sensitivity of about 100 dB and axial and lateral resolution of 24 mum and 14 mum, respectively. We imaged several phantom and biological samples using 1.3 mum and 1.7 microm OFDI systems and found that the depth-dependent signal decay rate is substantially lower at 1.7 microm wavelength in most, if not all samples. Our results suggest that this imaging window may offer an advantage over shorter wavelengths by increasing the penetration depths as well as enhancing image contrast at deeper penetration depths where otherwise multiple scattered photons dominate over ballistic photons.
The DKU Replay Detection System for the ASVspoof 2019 Challenge: On Data Augmentation, Feature Representation, Classification, and Fusion (2019)

This paper describes our DKU replay detection system for the ASVspoof 2019 challenge. The goal is to develop spoofing countermeasure for automatic speaker recognition in physical access scenario. We leverage the countermeasure system pipeline from four aspects, including the data augmentation, feature representation, classification, and fusion. First, we introduce an utterance-level deep learning framework for anti-spoofing. It receives the variable-length feature sequence and outputs the utterance-level scores directly. Based on the framework, we try out various kinds of input feature representations extracted from either the magnitude spectrum or phase spectrum. Besides, we also perform the data augmentation strategy by applying the speed perturbation on the raw waveform. Our best single system employs a residual neural network trained by the speed-perturbed group delay gram. It achieves EER of 1.04% on the development set, as well as EER of 1.08% on the evaluation set. Finally, using the simple average score from several single systems can further improve the performance. EER of 0.24% on the development set and 0.66% on the evaluation set is obtained for our primary system.
Influence of Maturity-onset Diabetes on Splanchnic Glucose Balance After Oral Glucose Ingestion (1978)

To determine the extent to which altered splanchnic glucose balance contributes to postprandial hyperglycemie in diabetes, splanchnic glucose exchange was determined in seven maturity-onset diabetics and 10 healthy control subjects in the basal state and for three hours following oral ingestion of 100 gm. of glucose. In the basal fasting state, arterial glucose levels in the diabetics (153±24 mg./100 ml.) were 75 to 80 mg./100 ml. higher than in controls while splanchnic glucose output was similar in the two groups (132 to 145 mg. per minute). Following glucose ingestion, arterial glucose concentration in the diabetics rose to peak levels (295 ±35 mg./100 ml.) that were 55 per cent higher than in controls and remained 100 to 125 mg./100 ml. above basal levels and 150 to 200 mg./100 ml. above control levels three hours after glucose. Splanchnic glucose output rose rapidly in the diabetics to values four times the basal rate at 15 to 30 minutes after glucose feeding and remained 60 per cent or more above basal levels throughout the three-hour period. In contrast, in the controls following a similar early rise, splanchnic glucose output returned to basal levels by 90 minutes. As a consequence, total splanchnic glucose output over three hours in the diabetics (53±4 gm.) was 33 per cent greater than in controls. In addition, the increment in splanchnic glucose output above basal levels in the diabetics (30±5 gm.) was 100 per cent greater than in controls and could account for 75 per cent of the augmented glucose accumulation in body fluids observed at three hours. It is concluded that in maturity-onset diabetics (1) net splanchnic glucose output is increased after glucose ingestion, suggesting that a greater proportion of an oral glucose load enters the systemic circulation than in healthy controls; (2) failure of splanchnic glucose retention is the major factor responsible for postprandial hyperglycémie in maturity-onset diabetes.
Optimising slanted-finger interdigital transducer (SFIT) filters (2002)

This paper presents an innovative design method for achieving a maximum performance in slanted-finger interdigital transducer (SFIT) filters by optimising certain parameters. This will lead to an improved performance as for example the mechanical reflections will not be only utilised to make the IDTs of the SFIT filter unidirectional but also to improve the filter response. For instance, passband ripple problems caused by triple transit echo may be prevented. Moreover, the skirt steepness may be increased without increasing the number of finger groups. In addition, the chip size can be reduced. This method will be compared with conventional design methods. Simulated and experimental results of some filter examples help to show the performance that can be achieved by this optimisation method. A fast analysis, which is necessary for optimising, has been developed. The method, which is based on a scaling principle to determine all P-matrix elements, is also described.
Development of Collaboration Environments onWeb 1.0 (2007)

In this study, a method to construct a collaboration environment is proposed and implemented. It has advantages such as (1) original web pages need not to be modified, and (2) the system requirement is adaptable, i.e. it is available on various operating systems and web browsers. Also, we will propose a way to utilize this method in e-Learning and how to enhance its efficiency.
Advance Selling for Services (2004)

Advance selling can be profitable when consumers are uncertain about their future consumption state. At the time of consumption, that uncertainty is resolved, but buyer states still remain unobservable to sellers. Consequently, buyer and seller information is symmetric in advance but asymmetric at consumption (i.e., sellers have an informational disadvantage in the consumption period relative to the advance period). Therefore, sellers can profit from transacting in the advance period when they are at less of a disadvantage. New technologies (e.g., biometrics, electronic tickets, smart cards, online prepayments, and new e-commerce technologies) also enhance the profitability of advance selling by lowering advance-selling costs and restraining arbitrage.
Hardwiring the Brain: Endocannabinoids Shape Neuronal Connectivity (2007)

The roles of endocannabinoid signaling during central nervous system development are unknown. We report that CB(1) cannabinoid receptors (CB(1)Rs) are enriched in the axonal growth cones of gamma-aminobutyric acid-containing (GABAergic) interneurons in the rodent cortex during late gestation. Endocannabinoids trigger CB(1)R internalization and elimination from filopodia and induce chemorepulsion and collapse of axonal growth cones of these GABAergic interneurons by activating RhoA. Similarly, endocannabinoids diminish the galvanotropism of Xenopus laevis spinal neurons. These findings, together with the impaired target selection of cortical GABAergic interneurons lacking CB(1)Rs, identify endocannabinoids as axon guidance cues and demonstrate that endocannabinoid signaling regulates synaptogenesis and target selection in vivo.
A spare capacity design method for restorable networks (2002)

To reroute the broken-down path in the event of transmission-line failure, it is necessary to construct a spare path network. This paper proposes an algorithm for the design of efficient spare path networks. This algorithm is a heuristic algorithm used to achieve near-optimization by repeating the movement to objective-function-value constant orientation and the value decrease orientation. Performance evaluation results show that the solution obtained with the proposed method is very close to the LP (linear programming) solution.
Thermally excited silicon microactuators (1988)

A cantilever-type micromachined silicon actuator based on the bimetal effect used extensively for the fabrication of temperature-controlled electrical switches is described. The silicon actuator consists of a Si-metal sandwich layer and an integrated poly-Si heating resistor as a driving element. Due to the low heat capacity of the transducer element, a high temperature increase per input power unit can be achieved. For a (Si-Au)-cantilever-type actuator, 500- mu m long and several micrometers thick, a specific deflection of approximately 0.1 mu m/K at the free end has been measured. The design considerations, fabrication process, and experimental results of the actuator are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Prediction of Survival in Multiple Myeloma Based on Gene Expression Profiles Reveals Cell Cycle and Chromosomal Instability Signatures in High-Risk Patients and Hyperdiploid Signatures in Low-Risk Patients: A Study of the Intergroupe Francophone du Myélome (2008)

Gene expression-based survival prediction and molecular features associated with high-risk patients may be useful for developing prognostic markers and may provide basis to treat these patients with new targeted antimitotics.
Effect of gelatin properties in complex coacervation processes (1992)

The effects of Bloom grade and iso-electric-point of gelatin on the complex coacervation with acacia and micro-encapsulation of theobromine were investigated. The zetapotential of various gelatins and acacia was measured at different pH values and compared with the optimal pH range for complex coacervation. Values for electrical equivalence pH of gelatins and acacia were in the same range as the maximal coacervate volumes. For the high Bloom grade gelatins the pH range in which most complex coacervate was formed was smaller for Alkaline-processed gelatin than for Acid-processed gelatins. The same small pH range was observed for the low Bloom grade gelatin of the Acid-type compared to high Bloom grade gelatins of the same type. The total amount of complex coacervate increased and the relative contents of theobromine in microcapsules decreased for gelatins with high Bloom grade. Microcapsules prepared with a high Bloom grade gelatin were irregular shaped and showed poor flow characteristics. No differences in theobromine release profiles from the various microcapsules were observed
Syntheses of N-Chlorobenzoyloxyalkylpiperidines* (1968)

N-オキシアルキルビペリジンとしてはN-(β-オキシエチル)ピペリジン[4],N-(β-オキシエチル)-2-メチルピペリジン[5]N-(β-オキシエチル)-2-メチル-5-エチルピペリジン[6],N-(γ-オキシプロビル)ピペリジソ[10],N-(γ-オキシプロピル)-2-メチルピペリジン[11],およびN-(γ-オキシブロピル)-2-メチル-5-エチルピペリジン[12]を使用した。[4],[5]および[6]はピペリジン,2-メチルピペリジソおよび2-メチル-5-エチルピベリジンとエチレソクロルヒドリンとの反応によってえられた。また[10].[11]および[12]はピペリジン,2-メチルピベリジンあるいは2-メチル-5-エチルピペリジソにアクリル酸エチルを付加反応してえられるN-(β エトキシカルボニルエチル)ピペリジン類の還元によってえられた,[4]と塩化m-クロルベンゾイルを55～60℃ で2時間加熱すると,N-(β-m-クロルベンゾイルオキシエチル)ピペリジン塩酸塩が83%の収率でえられた。同様にして[4],[5],[6],[10],[11]あるいは[12]を塩化o-,m-,p-クロルベンゾイル,塩化2,3-,2,6-,3,4および3,5-ジクロルベンゾイルによってアシル化するとそれぞれ相当するN-クロルベンゾイルオキシアルキルピペリジン塩酸塩類が15～90%の収率でえられた。
Analysis of cyclopropenoid and cyclopropanoid acids in fats and oils (1965)

Abstract The analysis of cyclopropenoid acids may be considered, from a historical standpoint, to have started with the discovery of the Halphen test. Although this test as orginally conceived was utilized as a means of detecting adulteration of premium edible oils with cottonseed oil, it has since been shown to be a characteristic test for cyclopropenoid fatty acids and has been adapted with various modifications as a quantitative colorimetric test for these substances. More recently, spectrophotometric methods particularly in the IR region have been applied to the analysis of these substances. The 9.8 Ɓ band, characteristic of the cyclopropane, and the 9.91 Ɓ band, characteristic of the cyclopropene group, as well as the 11.0 Ɓ band, characteristic of some of the noncyclic degradation derivatives, have been utilized. Gasliquid chromatography (GLC) has been applied to the methyl esters of cyclopropanoid and hydrogenated cyclopropenoid acids. The reactivity of the cyclopropene ring toward hydrohalogens has been the basis of several analytical methods developed for use with cyclopropene acid‐containing oils. Both aqueous and nonaqueous solutions of hydrohalogens have been employed. The hydrohalogenation methods are the most precise methods currently available for these analyses but only GLC has the inherent potential of identifying the specific cyclopropenoid or cyclopropenoids involved.