gebhart/patrepeval huggingface dataset:
Regulation of dopa decarboxylase expression during colour pattern formation in wild-type and melanic tiger swallowtail butterflies (1998)

The eastern tiger swallowtail butterfly Papilio glaucus shows a striking example of Batesian mimicry. In this species, females are either wild type (yellow and black) or melanic (where most of the yellow colour is replaced by black). In order to understand how these different colour patterns are regulated, we examined the temporal order of wing pigment synthesis via precursor incorporation studies, enzyme assays, and in situ hybridisation to mRNA encoding a key enzyme, dopa decarboxylase. We show that dopa decarboxylase provides dopamine to both of the two major colour pigments, papiliochrome (yellow) and melanin (black). Interestingly, however, dopa decarboxylase activity is spatially and temporally regulated, being utilised early in presumptive yellow tissues and later in black. Further, in melanic females, both dopa decarboxylase activity and early papiliochrome synthesis are suppressed in the central forewing and this normally yellow area is later melanised. These results show that the regulation of enzyme synthesis observed in the yellow/black pattern of a single wing, is similar to that involved in melanism. We infer that dopa decarboxylase activity must be regulated in concert with downstream enzymes of either the melanin and/or the papiliochrome specific pathways, forming part of a developmental switch between yellow or black. This modification of multiple enzyme activities in concert is consistent with a model of melanisation involving coordinate regulation of the underlying synthetic pathways by a single Y-linked (female) factor.
Honest signals in video conferencing (2011)

We propose a novel system to analyze gestural and nonverbal cues of participants in video conferencing. These cues have previously been referred to as “honest signals” and are usually associated with the underlying cognitive state of the participants. The presented system analyzes a set of audio-visual, non-linguistic features in real time from the audio and video streams of two participants in a video conference. We show how these features can be used to compute indicators of the overall quality and type of conversation being held. The system also provides visual feedback to the participants, who then have the choice of modifying their conversational style in order to achieve the desired outcome of the video conference. Experiments on real-life data show that the system can predict the type of conversation with high accuracy using the non-linguistic signals only. Qualitative user studies highlight the positive effects of increased awareness amongst the participants about their own gestural and non-verbal cues.
Deformable Markov model templates for time-series pattern matching (2000)

Article Free Access Share on Deformable Markov model templates for time-series pattern matching Authors: Xianping Ge Information and Computer Science, University of California, Irvine, Irvine, CA Information and Computer Science, University of California, Irvine, Irvine, CAView Profile , Padhraic Smyth Information and Computer Science, University of California, Irvine, Irvine, CA Information and Computer Science, University of California, Irvine, Irvine, CAView Profile Authors Info & Claims KDD '00: Proceedings of the sixth ACM SIGKDD international conference on Knowledge discovery and data miningAugust 2000 Pages 81–90https://doi.org/10.1145/347090.347109Published:01 August 2000Publication History 115citation1,388DownloadsMetricsTotal Citations115Total Downloads1,388Last 12 Months76Last 6 weeks8 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Toward maser action at room temperature by triplet-radical interaction and its application to microwave technology (2002)

The interaction between photoinduced triplets and stable radicals, in liquid solutions at room temperature, is utilized to control the macroscopic permeability of these systems. Based on a numerical-theoretical treatment, which describes this photoprocess, the changes in the permeability can be optimized by choosing the appropriate chemical system. Presently, we can demonstrate how these light-driven changes result in noticeable changes in the reflection coefficient (amplitude and phase) of a microwave cavity containing the chemical system. This effect can lead the way to ultra low noise microwave amplifiers and low-loss microwave phase shifters, operating at room temperature with very low spin temperature, e.g. ,T s < 16 K.
Monaural Sound Localization Based on Reflective Structure and Homomorphic Deconvolution (2017)

The asymmetric structure around the receiver provides a particular time delay for the specific incoming propagation. This paper designs a monaural sound localization system based on the reflective structure around the microphone. The reflective plates are placed to present the direction-wise time delay, which is naturally processed by convolutional operation with a sound source. The received signal is separated for estimating the dominant time delay by using homomorphic deconvolution, which utilizes the real cepstrum and inverse cepstrum sequentially to derive the propagation response's autocorrelation. Once the localization system accurately estimates the information, the time delay model computes the corresponding reflection for localization. Because of the structure limitation, two stages of the localization process perform the estimation procedure as range and angle. The software toolchain from propagation physics and algorithm simulation realizes the optimal 3D-printed structure. The acoustic experiments in the anechoic chamber denote that 79.0% of the study range data from the isotropic signal is properly detected by the response value, and 87.5% of the specific direction data from the study range signal is properly estimated by the response time. The product of both rates shows the overall hit rate to be 69.1%.
Electrochemistry and spectroscopy of ortho-metalated complexes of iridium(III) and rhodium(III) (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemistry and spectroscopy of ortho-metalated complexes of iridium(III) and rhodium(III)Y. Ohsawa, S. Sprouse, K. A. King, M. K. DeArmond, K. W. Hanck, and R. J. WattsCite this: J. Phys. Chem. 1987, 91, 5, 1047–1054Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/j100289a009https://doi.org/10.1021/j100289a009research-articleACS PublicationsRequest reuse permissionsArticle Views2320Altmetric-Citations263LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
PUTTING IVHS TO WORK TO ENHANCE SAFETY (1993)

The author promotes the belief that Intelligent Vehicle Highway Systems ( IVHS) provides the opportunity to develop and deploy active safety systems that help drivers avoid crashes or reduce the severity of crashes that do occur. A brief discussion ensues on the causes of crashes, solutions for avoiding crashes, and the importance of user interface.
Patterning two-dimensional chalcogenide crystals of Bi2Se3 and In2Se3 and efficient photodetectors (2015)

Patterning of high-quality two-dimensional chalcogenide crystals with unique planar structures and various fascinating electronic properties offers great potential for batch fabrication and integration of electronic and optoelectronic devices. However, it remains a challenge that requires accurate control of the crystallization, thickness, position, orientation and layout. Here we develop a method that combines microintaglio printing with van der Waals epitaxy to efficiently pattern various single-crystal two-dimensional chalcogenides onto transparent insulating mica substrates. Using this approach, we have patterned large-area arrays of two-dimensional single-crystal Bi2Se3 topological insulator with a record high Hall mobility of ∼1,750 cm(2) V(-1) s(-1) at room temperature. Furthermore, our patterned two-dimensional In2Se3 crystal arrays have been integrated and packaged to flexible photodetectors, yielding an ultrahigh external photoresponsivity of ∼1,650 A W(-1) at 633 nm. The facile patterning, integration and packaging of high-quality two-dimensional chalcogenide crystals hold promise for innovations of next-generation photodetector arrays, wearable electronics and integrated optoelectronic circuits.
Controlled synthesis of amphiphilic block copolymers with pendant glucose residues by living cationic polymerization (1997)

Amphiphilic block copolymers of vinyl ethers (VEs) of the type —[CH2CH(OCH2CH2OR)]m—[CH2CH(OiBu)]n—were synthesized by living cationic polymerization, where R is a D-glucose residue, and m and n are the degrees of polymerization (m = 20–50; n = 11–89). To obtain them, sequential living block copolymerization of isobutyl vinyl ether (IBVE) and the vinyl ether carrying 1,2:5,6-diisopropylidene-D-glucose residue was conducted by using the HCl adduct of IBVE, CH3CH(OiBu)Cl, as initiator in conjunction with zinc iodide. These precursor block copolymers had a narrow molecular weight distribution (M̄w/M̄n ∼ 1.1) and a controlled composition. Treatment of them with a trifluoroacetic acid/water mixture led to the target amphiphiles. The solubility of the amphiphilic block copolymers in various solvents depended strongly on composition or the m/n ratio. Their solvent-cast thin films were observed, under a transmission electron microscope, to exhibit various microphase-separated surface morphologies such as spheres, cylinders, and lamellae, depending on composition. © 1997 John Wiley & Sons, Inc.
The future of rock physics: computational methods vs. lab testing (2008)

Jack Dvorkin,Meghan Armbruster, Chuck Baldwin, Qian Fang, Naum Derzhi, Carmen Gomez, Boaz Nur, Amos Nur, and Yaoming Mu propose the novel use of a virtual rock physics laboratory as a pragmatic way to improve the quantifying and understanding rock without damaging the usefulness of rock samples for further experimentation.
Δ<sup>4,4‘</sup>-Dicyclopenta[2,1-<i>b</i>:3,4-<i>b</i>‘]dithiophene. A Conjugated Bridging Unit for Low Band Gap Conducting Polymers (2003)

Δ4,4‘-Dicyclopenta[2,1-b:3,4-b‘]dithiophene has been prepared from cyclopenta[2,1-b:3,4-b‘]bithiophen-4-one and its electrochemical and spectroscopic properties have been characterized. Its low HOMO−LUMO gap and facile electrochemical polymerization make it an attractive building block for low band gap conducting polymers. Films of poly-(Δ4,4‘-dicyclopenta[2,1-b:3,4-b‘]dithiophene) on electrodes have been characterized by cyclic voltammetry, electronic absorption spectroscopy, IR spectroscopy, and in situ conductivity measurements. The spectroscopic and electrochemical results confirm the formation of a polymeric material with long conjugation length and low band gap (ca. 0.5 eV). The intrinsic conductivity is consistent with this band gap.
CD40L is important for induction of, but not response to, costimulatory activity. ICAM-1 as the second costimulatory molecule rapidly up-regulated by CD40L (1996)

The CD40 ligand (CD40L):CD40 interaction plays an important role in the activation of both T and B cells. However, the mechanisms by which this interaction is involved in activation of T cells is still unclear. Here we show that CD40L is not essential for T cell response to TCR engagement if the APC have costimulatory activity, although it is essential for T cell-mediated induction of such costimulatory activity. To determine the molecular basis of this activity, we have produced three mAbs that appear to recognize the costimulatory molecules rapidly induced by CD40L. Two of them recognize CD44H, which we showed to have CD28-independent costimulatory activity for T cells. The molecule recognized by the remaining mAb is hereby identified as ICAM-1. Furthermore, ICAM-1-mediated costimulation is likely to serve for a function similar to that mediated by the B7:CD28 interaction, as targeted mutation of CD28 renders T cell responses to Con A more dependent on ICAM-1.
REgulation of insulin binding to isolated hepatocytes: correction for bound hormone fragments linearizes Scatchard plots. (1980)

Fragments of 125I-labeled insulin (125I-insulin) are rapidly produced after the initial cell binding process. After association of 125I-insulin with hepatocytes, hormone fragments remain bound to cells. At 23 degrees C, approximately 20% of the label bound at steady state was soluble in trichloroacetic acid. Correction of saturation experiments for the presence of bound trichloroacetic acid-soluble insulin fragments decreased the number and increased the affinity of 125I-insulin-binding sites. Label extracted from cell pellets recovered from saturation experiments was characterized by gel filtration; 59%, 55%, 40%, and 36% of the bound label was from intact hormone after recovery from incubation mixtures containing 0.18, 0.60, 4.6, and 7.5 nM applied 125I-insulin, respectively. At high applied 125I-insulin concentrations, the hormone predominantly interacted with lower affinity degradation systems. When binding data were corrected to assay for undegraded 125I-insulin only, curvilinear Scatchard plots were linearized. The insulin receptor is therefore not composed of heterogeneous or negatively cooperative sites. It is necessary to correct for retained fragments of 125I-insulin in order to define mechanisms through which hormone binding and cellular response may be regulated.
[Clinical analysis on adult acute T-lymphoblastic leukemia]. (2012)

This study was aimed to summarize and analyze the clinical features and biological characteristics of adult acute T-lymphoblastic leukemia (T-ALL), and compare the efficacy of chemotherapy and transplantation in order to explore the factors influencing the long term survival and prognosis. Twenty-two T-ALL patients, all of whom were initially diagnosed according to MICM classification criteria from May 2000 to May 2010, were enrolled in this study. All patients received VDCLP regimen as the induction chemotherapy. In consolidation stage, some of the patients received allogeneic hematopoietic stem cell transplantation (allo-HSCT) and the others underwent intensive chemotherapy. The clinical and laboratory parameters were summarized and the contribution to survival and efficacy was analyzed by using χ(2) test, Kaplan-Meier method, Cox regression analysis and log-rank test with the aid of SPSS13.0 software. The results showed that: (1) The median age of all 22 patients was 23.5 years (16 - 63 years). 15 patients with splenomegaly had much shorter event-free survival (EFS) period (P = 0.014) and overall survival (OS) period (P = 0.013). The median white blood cell (WBC) count was 148.82 (5.51-546.0) × 10(9)/L. 15 cases out of them had leucocytosis (WBC ≥ 80 × 10(9)/L), whose EFS period (P = 0.021) and OS time (P = 0.050) were reduced significantly. The similar condition was observed in 6 patients whose blood platelet (Plt) count was no more than 30 × 10(9)/L (P = 0.033 for EFS and P = 0.035 for OS, respectively); (2) Immunophenotypic analysis showed that from 22 cases 2 cases were of pro-T, 14 cases of pre-T, 3 cases of cortical-T and 3 cases of medullary-T. Supposing pro-T and pre-T as earlier period immunophenotype, cortical-T and medullary-T as advanced stage immunophenotype, there were significant differences between earlier period and advanced stage patients in terms of EFS and OS (P = 0.035 for EFS and P = 0.028 for OS, respectively); (3) Chromosome karyotype was analyzed in 19 cases at diagnosis, and among them 12 cases had normal karyotypes while abnormal karyotypes were observed in 7 cases. Correlation analysis showed that there were no significant differences between these two groups in time of EFS and OS; (4) The overall complete remission (CR) rate was 72.7 after the induction chemotherapy. The median CR period was 18.0 months. The EFS and OS rate were 57.9 and 67.1 for 1-year, and 23.0 EFS rate and 22.0 OS rate for 3-years, respectively. Six patients received allo-HSCT and the average EFS time and OS time were both 57.8 months, which were significantly longer than those of the intensive chemotherapy group (P = 0.001 and P = 0.002 for EFS and OS, respectively); (5) Cox regression analysis proved that allo-HSCT treatment was the independent favorable prognostic factor. It is concluded that higher CR rate can be achieved by using intensive induction chemotherapy in adult T-ALL, but the long term survival seems poor by chemotherapy only in consolidation treatment stage. Allo-HSCT is the optimal choice to improve the prognosis and the outcome.
Software pattern communities (2007)

Software pattern designers and users have few resources available to support pattern-based development practices. Patterns are currently disseminated in disjoint collections in various publishing mediums with little or no technology support. As the number of patterns and diversity of pattern types continue to proliferate, pattern users and developers are faced with difficulties of understanding what patterns already exist and when, where, and how to use or reference them properly. This defeats the very purpose of patterns as a medium to encapsulate and disseminate recurring design experiences. In this paper, an initial study among a set of pattern collections is performed to better understand the difficulties related to improve pattern-based support for software development activities. Based on the empirical survey, challenges are identified that define impediments to the federation of software patterns into an interconnected body of knowledge. A Semantic Web ontology is presented as an initial attempt at solving some of these issues through the use of Web-based ontologies.
Minimizing Soft Errors in TCAM Devices: A Probabilistic Approach to Determining Scrubbing Intervals (2009)

Ternary content addressable memory (TCAM) is more susceptible to soft errors than static random access memory (SRAM). The large di/dt issue during comparison operation reduces operating voltage ranges, which in turn reduces soft error immunity. The tight structural coupling of TCAM comparison circuits and memory cells does not allow for an interleaving design scheme in mitigating soft errors. Regular scrubbing of stored content can greatly mitigate the reliability issue caused by soft errors. However, frequent scrubbing can also affect device performance. The scrubbing interval should be determined to facilitate both reliability and performance. This paper proposes a novel, model-based approach that includes both single-bit upsets (SBUs) and multi-cell upsets (MCUs) to determine the scrubbing interval by predictive and probabilistic failure rate analysis. This model uses the compound Poisson (CP) process to count clustered random events, which are common phenomena of soft errors in technologies that use chips under 90 nm. The 20 M TCAM with 90-nm CMOS technology was tested with 180-MeV neutron strikes. The scrubbing interval determined based on the proposed model is applied to the TCAM test results. The failure probabilities based on the CP model showed 31% overestimation on average compared to the same from the test data. Such overestimation is mainly due to the independent upset assumption in the proposed model and can enable use of the model as worst case analysis. The worst case comparison with the test data showed 1.7% overestimation, which can tell the proposed model is effective in predicting upper-bound soft error reliability.
Irinotecan therapy and molecular targets in colorectal cancer: A systemic review (2009)

Irinotecan is the second line chemotherapy for advanced stage colorectal cancer (CRC) after failure of first line chemotherapy with oxaliplatin and 5-fluorouracil. The aim of this review is to analyse the data on irinotecan as second line chemotherapy for advanced CRC and the potential roles of the molecular markers, p53 and vascular endothelial growth factor (VEGF) in the management of advanced CRC. Thus, the English literature from 1980 to 2008 concerning irinotecan, p53, VEGF and CRC was reviewed. On review, Phase II and III clinical trials showed that irinotecan improves pain-free survival, quality of life, 1-year survival, progression-free survival and overall survival in advanced CRC. p53 and VEGF were expressed in CRC and had a predictive power of aggressive clinical behaviour in CRC. Irinotecan sensitizes p53 wild type, mutant and null cells to Fas-mediated cell apoptosis in CRC cells. Wild type p53 cells were more sensitive to irinotecan than mutated p53. Irinotecan has an anti-VEGF effect inhibiting endothelial cell proliferation, increasing apoptosis and reducing microvascular density which is only limited by irinotecan toxicity levels. To conclude, irinotecan improves the patient's quality of life and the survival rates of patients with advanced CRC. p53 and VEGF status of the patients' tumour is likely to affect the responsiveness of CRC to irinotecan. It is recommended that studies of the expression of these molecular markers in relation to chemo-responsiveness of irinotecan should be carried out for better management of patients with advanced CRC.
Synthesis of new calixcrowns and their anchoring to silica gel for the selective separation of Cs+ and K+ (1996)

New 1,3-alternate calix[4]arenecrown-6 and calix[4]arenecrown-5, which are selective for caesium and potassium ions respectively, have been synthesized and linked covalently to silica gel via hydrosilanization and successfully employed for the chromatographic separation of Cs+ and K+ from alkali metal ions.
Infrared Recycler (2000)

Salyp N.V., an automotive recycling company in Eiper, Belgium, has developed a mechanical sorting system whose purpose is to recover the mixed thermoplastic portion of automotive shredder residue. Salyp is marketing franchises of its recycling technology to automotive shredders worldwide. The company also envisions an End-of-Life Vehicle (ELV) Foundation, in which auto shredder customers and other interested groups, including government agencies, will help to establish standards for thermoplastics that are reclaimed from auto-shredder residue. Yet the company must overcome a tough hurdle if it’s going to sell its idea to the estimated 200 auto shredders that do business in the United States. A specific section within the law prohibits the manufacture, processing, use or reuse, or distribution in commerce of printed circuit boards (PCB). Salyp plans to combine its thermoplastic sorting system with a system developed by Argonne Lab for the recycling of polyurethane foam. Foam is the third material stream, after metal oxides and thermoplastics, in the initial sorting of shredder waste.