gebhart/patrepeval huggingface dataset:
Coherent optical emitters in diamond nanostructures via ion implantation (2015)

The negatively-charged silicon-vacancy ($\mathrm{SiV}^{-}$) center in diamond is a bright source of indistinguishable single photons and a useful resource in quantum information protocols. Until now, $\mathrm{SiV}^{-}$ centers with narrow optical linewidths and small inhomogeneous distributions of $\mathrm{SiV}^{-}$ transition frequencies have only been reported in samples doped with silicon during diamond growth. We present a technique for producing implanted $\mathrm{SiV}^{-}$ centers with nearly lifetime-limited optical linewidths and a small inhomogeneous distribution. These properties persist after nanofabrication, paving the way for incorporation of high-quality $\mathrm{SiV}^{-}$ centers into nanophotonic devices.
[Deep frozen fresh plasma in blood component therapy: preparation--quality control--indications]. (1981)

Fresh frozen plasma is prepared within 6 hrs after collection in a double bag system. A second centrifugation at 4600 x g is necessary to obtain a platelet poor plasma. A special bag freezing system fitted to a conventional cryostat and cooled with ethanol to -50 degrees C was developed to reach the required cooling rate. It is possible to freeze 25 plasma bags simultaneously within 30 min in this new apparatus. Fresh frozen plasma prepared in this manner contains all coagulation factors and inhibitors with almost normal activities. Freezing at -40 degrees C in the air, prolonged storage of the starting material, or insufficient cooling of the frozen product deteriorate its quality. The influence of these variables with the discussed in detail. Indications of fresh frozen plasma, especially for dilution- and posttraumatic consumption coagulopathy as well as liver disease, are presented.
Hydrofoil operational performance enhancement using hybrid design options (1978)

For a number of years the David Taylor Naval Ship R&D Center, with support from the Naval Sea Systems Command, has engaged in investigations of hybrid interface vehicle concepts having potential for naval applications. This work has resulted in interesting design options, some of which can broaden and enhance the performance characteristics of vehicles supported by combinations of buoyancy and dynamic lift (hydrofoils). Hydrofoil ships with full load displacements from about 250 to 4000 tons having buoyancy/fuel tanks of various sizes attached to their foil systems were investigated. Analyses performed to date have considered modifications to conventional, fully-submerged hydrofoils by reducing maximum speed and adding fuel stored in an external tank suspended from the strut/foil system. While this may require more installed horsepower, there is an improvement in range for hydrofoils larger than 200 to 300 tons. The range improvement increases for ships of larger size. Also of significance is the extension of the lower foilborne speed boundary. Design full load buoyancy of 50% or greater was found to offer good potential for performance enhancement of foilborne ships. Maximum calm water foilborne speed was estimated to be 40 to 45 knots, depending on design speed and fuel load. Hullborne range of hydrofoils with a large buoyancy/fuel tank was also found to be greater than that of a comparable conventional hydrofoil. A specific study was made to demonstrate the capability of extending the hydrofoil operational envelope by modifying the PCH-1 (HIGH POINT) hydrofoil. Results of a computer simulation and initial structural analyses, as well as a planned model test program for PCH-1 with a six-foot (1.83-meter) diameter, 100-foot (30.48-meter) long tank are described.
E Proteins and Id2 Converge on p57<sup>Kip2</sup> To Regulate Cell Cycle in Neural Cells (2006)

A precise balance between proliferation and differentiation must be maintained during neural development to obtain the correct proportion of differentiated cell types in the adult nervous system. The basic helix-loop-helix (bHLH) transcription factors known as E proteins and their natural inhibitors, the Id proteins, control the timing of differentiation and terminal exit from the cell cycle. Here we show that progression into S phase of human neuroblastoma cells is prevented by E proteins and promoted by Id2. Cyclin-dependent kinase inhibitors (CKI) have been identified as key effectors of cell cycle arrest in differentiating cells. However, p57Kip2 is the only CKI that is absolutely required for normal development. Through the use of global gene expression analysis in neuroblastoma cells engineered to acutely express the E protein E47 and Id2, we find that p57Kip2 is a target of E47. Consistent with the role of Id proteins, Id2 prevents activation of p57Kip2 expression, and the retinoblastoma tumor suppressor protein, a known Id2 inhibitor, counters this activity. The strong E47-mediated inhibition of entry into S phase is entirely reversed in cells in which expression of p57Kip2 is silenced by RNA interference. During brain development, expression of p57Kip2 is opposite that of Id2. Our findings identify p57Kip2 as a functionally relevant target recruited by bHLH transcription factors to induce cell cycle arrest in developing neuroblasts and suggest that deregulated expression of Id proteins may be an epigenetic mechanism to silence expression of this CKI in neural tumors.
Influencia de los defectos de la visión en colorimetría dental (2009)

OBJETIVOS 1. Comprobar si existen errores de refraccion en odontologos de pregrados. 2. Comprobar si hay transtornos del color en odontologos de pregrado. 3. Verificar si estos transtornos de la vision condicionan la vision del color dental. 4. Comprobar si existen diferencias entre una medicion objetiva del color y una medicion subjetiva y con trastornos. 5. Abrir nuevas vias de estudio en este campo tan desconocido.
Application of the Aza-Achmatowicz Oxidative Rearrangement for the Stereoselective Synthesis of the <i>Cassia</i> and <i>Prosopis</i> Alkaloid Family (2006)

cis-2-Methyl-6-substituted piperidin-3-ol alkaloids of the Cassia and Prosopis species are readily prepared by a combination of an aza-Achmatowicz oxidative rearrangement and dihydropyridone reduction followed by a stereoselective allylsilane addition to a N-sulfonyliminium ion. The stereochemical outcome of the reduction reaction can be attributed to steric hindrance between the pseudoaxially oriented 2,6-substituents and the equatorially approaching hydride reagent which explains the exclusive formation of the cis-alcohol by axial approach of the hydride. The unsaturation present in the (E)-methyl-pent-3-enoate side chain was removed by catalytic reduction, and the remaining ester group was converted to the corresponding Weinreb's amide. This key intermediate was utilized for the synthesis of azimic acid, deoxocassine, cassine, and spicigerine. The facile preparation of (S)-N-tosylamidofuran 16 and its conversion to the chiral Achmatowicz oxidation product 18 provide a formal chiral synthesis of these alkaloids.
Stroboscopic white-light interference microscopy (2006)

The principle of stroboscopic motion freezing of oscillating objects extends directly to interference microscopes that use coherence as part of the measurement principle. Analysis shows, however, that the fringe contrast loss for out-of-plane motion in stroboscopic interferometry is a wavelength-dependent phenomenon, which can alter the apparent nominal center wavelength of the white-light source. As in monochromatic systems, the key adjustable parameter is the duty cycle, equal to the product of the vibrational frequency and the pulse width. This theoretical study provides detailed graphs of expected errors as a function of the duty cycle, including fringe contrast loss, apparent wavelength shift, and measurement error.
THE EVOLUTION OF THE SONOBUOY FROM WORLD WAR II TO THE COLD WAR (2014)

The primary airborne anti-submarine warfare sensor, the expendable sonobuoy, was developed during World War II in response to the devastating destruction of Allied shipping in the Atlantic caused by German U-boats. The simple radio-linked listening device thrown out of an aircraft in the 1940s proved revolutionary for air ASW. During the decades that followed, the evolution of the acoustic sonobuoy followed a number of directions. From the AN/CRT-1, the first passive omnidirectional broadband sonobuoy of World War II, to the AN/SSQ-53 DIFAR and AN/SSQ-77 VLAD, passive directional narrowband sonobuoys, and the AN/SSQ-62 DICASS, an active directional sonobuoy, of the Cold War, sonobuoys evolved in capability and tactical deployment in response to the increasingly sophisticated Soviet submarine threat. The development of the sonobuoy with its improving technology and in its multiple manifestations is described in counterpoint to the developing threat. The advance of operational concepts from CODAR to Julie and Jezebel to DIFAR are illustrated, and the influence of advances in underwater acoustics and the ocean environment upon sonobuoy design are discussed. The sonobuoy is shown to be a simple, reliable, inexpensive, technically complex, adaptive, and effective device that has been produced by the millions and used for almost seventy years.
A flexible ultrasonic array incorporating a platelet composite transmitter-theory and experiment (1993)

The surface conforming qualities of flexible ultrasonic arrays makes them ideally suited to non-destructive testing (NDT) of non-planar and curved surface topographies. The proposed array is a hybrid device that combines the transmission sensitivity of ceramic/polymer composites, with the high bandwidth reception properties of PVDF. Experimental impedance characteristics and thickness mode modelling techniques suggest that a transmit element incorporating ceramic platelets may provide a compromise between flexibility and ease of manufacture. A surface scattering model has been developed that may be used to assess the influence of factors such as interelement spacing on the array's potential imaging performance. This paper discusses the rationale behind the design procedure. An array is then constructed based on this analysis and a series of experimental results is presented
Quantitative depth profiling of ultrathin high-k stacks with full spectrum time of flight–secondary ion mass spectrometry (2011)

Elemental concentration depth profiles of high-k material stacks for 32 nm node devices and below were acquired by high resolution backscattering spectrometry (HRBS), parallel angle resolved-x-ray photoelectron spectroscopy (pAR-XPS), and time of flight–secondary ion mass spectrometry (ToF-SIMS). ToF-SIMS data were analyzed using an original calibration method which the authors shall refer to as the full spectrum protocol. Three different samples were studied in this work, one ultrathin insulating layer (IL) alone and two nitridized high-k/IL samples with different nitridation conditions for the IL. Although HRBS and AR-XPS already proved their ability in this domain, SIMS or ToF-SIMS characterization of high-k material stacks is still hampered by various matrix effects. Comparison of the elemental profiles obtained by all three techniques allows the accuracy of the full spectrum ToF-SIMS protocol to be assessed, both in terms of chemical composition quantification and depth resolution. This study reveals the feasibility of quantitative and depth resolved ToF-SIMS profiling of ultrathin high-k material stacks.
Design and Fabrication of a Micro Electrostatic Vibration-to-Electricity Energy Converter (2007)

This paper presents a micro electrostatic vibration-toelectricity energy converter. For the 3.3 V supply voltage and 1cm2 chip area constraints, optimal design parameters were found from theoretical calculation and Simulink simulation. In the current design, the output power is 200 $μ$W/cm2 for the optimal load of 8 MΩ. The device was fabricated in a silicon-on-insulator (SOI) wafer. Mechanical and electrical measurements were conducted. Residual particles caused shortage of the variable capacitor and the output power could not be measured. Device design and fabrication processes are being refined.
Patterns of antibody specificity during the BALB/c immune response to hen eggwhite lysozyme (1992)

We tested 49 BALB/c antilysozyme mAb from seven intervals during the immune response to lysozyme for patterns of specificity and avidity. We found that the antibody epitopes in composite covered at least 80% of the lysozyme surface, and their patterns of overlap suggest a continuum of potential antibody epitopes. Previously observed regional specificities, which emerged at different times in the immune response, were more discretely defined in late response antibodies, when the majority of mAb could be assigned to one of three functionally nonoverlapping complementation groups. The area covered by each antigenic region may be greater than an individual epitope, and may include multiple epitopes that overlap structurally and functionally to varying degrees. Connectivity between antigenic regions was seen in interactions among early and late stage antibodies, and among secondary stage mAb, but not among tertiary stage mAb from hyperimmunized mice. Patterns of overlap of early and late response antibodies suggest that the organization of antibody specificities change during the progression from primary to secondary to tertiary response. Over the same period in the response, the average relative avidity of IgG1 kappa mAb did not increase, suggesting that "affinity maturation" of serum antibodies reflects an increase in the number and diversity of antibodies, rather than an overall increase in the avidity of individual antibodies.
MCDB: Using Multi-clouds to Ensure Security in Cloud Computing (2011)

Security is considered to be one of the most critical aspects in a cloud computing environment due to the sensitive and important information stored in the cloud for users. Users are wondering about attacks on the integrity and the availability of their data in the cloud from malicious insiders and outsiders, and from any collateral damage of cloud services. These issues are extremely significant but there is still much room for security research in cloud computing. This paper focuses more on the issues related to the data security and privacy aspects in cloud computing, such as data integrity, data intrusion, service availability. It proposes a Multi-clouds Database Model (MCDB) which is based on Multi-clouds service providers instead of using single cloud service provider such as in Amazon cloud service. In addition, it will discuss and present the architecture of the proposed MCDB model and describe its components and layers. The results and implementation for the new proposed model will be analyzed, in relation to addressing the security factors in cloud computing, such as data integrity, data intrusion, and service availability.
Skin smoothing effects of Dead Sea minerals: comparative profilometric evaluation of skin surface (1997)

The skin smoothing effects of three different liquid gels were compared on 20 mature women. Treatment applications were performed twice a day over a period of 4 weeks, and the skin roughness parameter (Rz) of all test participants was determined at the beginning and at the end of the study using a computer‐aided laser profilometry, in accordance with DIN 4768 ff. At the end of the application period, the liquid gel with 1% of a Dead Sea mineral solution had an average skin roughness parameter reduction of 40.7%. The liquid gel without mineral additives showed an average reduction in skin roughness of 27.8%. The control gel without anti‐wrinkle agents or the additives showed an average reduction of only 10.4%. Resume. On a teste l'influence d'une formulation aux liposomes d'un melange ceramide/phospholipide sur la fonction protectrice de la peau de personnes en test atopique, avec une peau saine, et apres extraction lipidique. On a utilise la perte d'eau transepidermique et l'hydratation de l'epiderme comme parametres d'evaluation de l'influence du traitement sur la fonction protectrice. On a en outre effectue apres application un test de la fonction protectrice avec un ester d'acide nicotinique. On a constate des effets stabilisateurs de la fonction protectrice apres application seulement sur peau atopique et apres extraction lipidique mais pas sur peau saine. Les resultats nous conduisent a esperer des effets positifs uniquement en cas d'alteration de la fonction protectrice.
Human C5a and C5a des Arg exhibit chemotactic activity for fibroblasts. (1988)

C5a and C5a des Arg are chemotactic factors for inflammatory cells but it is not known whether these agents are chemoattractants for fibroblasts. Accordingly, C5a, purified from zymosan-activated human, and C5a des Arg, prepared by incubating C5a with immobilized porcine carboxypeptidase B, were studied for fibroblast chemotactic activity. We observed that both C5a and C5a des Arg stimulated human skin fibroblasts and fetal bovine ligament fibroblasts to migrate in a concentration-dependent fashion, and that the migratory responses were similar in magnitude to the responses achieved with optimal concentrations of two known fibroblast chemoattractants, platelet-derived growth factor and human fibrinopeptide B. The peak responses to C5a and C5a des Arg occurred at approximately 10(-9)M. With ligament fibroblasts, there was a greater response to C5a des Arg than to C5a, but with human fibroblasts there was no difference. Cochemotaxin, which enhances the chemotactic activity of C5a des Arg for neutrophils, had no effect on C5a des Arg fibroblast chemotactic activity but appeared to increase the fibroblast chemotactic activity of C5a. These results indicate that the effects of C5a and C5a des Arg in vivo may extend to the recruitment of mesenchymal cells. Moreover, the findings represent another example of an activity retained by C5a after removal of its carboxyl terminal arginine.
Data abstraction from a programming language viewpoint (1980)

This paper traces the development of data abstraction concepts in programming languages. A data abstraction, or abstract data type, describes a collection of abstract entities and operations on the entities. A program which uses a data abstraction can access or modify the entities only through the abstract operations.
Electronic Properties of Polyoxometalates:  Electron and Proton Affinity of Mixed-Addenda Keggin and Wells−Dawson Anions (2002)

A series of systematic DFT calculations were conducted on Keggin [SiW(9)M(3)O(40)](n-), M = Mo, V, and Nb; and Wells-Dawson anions [P(2)M(18)O(62)],(6-) M = W and Mo; [P(2)M(15)M(3)'O(62)](m-), M = W and Mo, M' = W, Mo, and V to analyze the redox properties and the basicity of the external oxygen sites in polyoxometalates with nonequivalent addenda metals. The energy and composition of the lowest unoccupied orbitals, formally delocalized over the addenda atoms, determine the redox properties of a polyoxometalate. When a Mo(6+) substitutes one W(6+) in the 1:12 tungstate, the energy of the LUMO decreases and the cluster is more easily reduced. The tungstoniobates behave differently because the niobium orbitals insert into the tungsten band and the reduction of [SiW(9)Nb(3)O(40)](7-) yields the blue species SiW(9)Nb(3) 1e and not the cluster SiW(9)Nb(2)Nb(IV). In Wells-Dawson structures, the polar and equatorial sites have different electron affinities and the reduction preferentially occurs in the equatorial sites. Inserting ions with larger electron affinities into the polar sites can modify this traditional conduct. Hence, the trisubstituted [P(2)W(15)V(3)O(62)](9-) anion is reduced in the vanadium polar sites. By means of molecular electrostatic potential maps and the relative energy of the various protonated forms of [SiW(9)V(3)O(40)](7-) and [SiW(9)Mo(3)O(40)](4-), we established the basicity scale: OV(2) > OMo(2) > OW(2) > OV > OW > OMo. Finally, a continuum model for the solvent enabled us to compare anions with different total charges.
Single cell manipulation, analytics, and label‐free protein detection in microfluidic devices for systems nanobiology (2005)

Single cell analytics for proteomic analysis is considered a key method in the framework of systems nanobiology which allows a novel proteomics without being subjected to ensemble-averaging, cell-cycle, or cell-population effects. We are currently developing a single cell analytical method for protein fingerprinting combining a structured microfluidic device with latest optical laser technology for single cell manipulation (trapping and steering), free-solution electrophoretical protein separation, and (label-free) protein detection. In this paper we report on first results of this novel analytical device focusing on three main issues. First, single biological cells were trapped, injected, steered, and deposited by means of optical tweezers in a poly(dimethylsiloxane) microfluidic device and consecutively lysed with SDS at a predefined position. Second, separation and detection of fluorescent dyes, amino acids, and proteins were achieved with LIF detection in the visible (VIS) (488 nm) as well as in the deep UV (266 nm) spectral range for label-free, native protein detection. Minute concentrations of 100 fM injected fluorescein could be detected in the VIS and a first protein separation and label-free detection could be achieved in the UV spectral range. Third, first analytical experiments with single Sf9 insect cells (Spodoptera frugiperda) in a tailored microfluidic device exhibiting distinct electropherograms of a green fluorescent protein-construct proved the validity of the concept. Thus, the presented microfluidic concept allows novel and fascinating single cell experiments for systems nanobiology in the future.
Compact Beam-Steerable Lens Antenna for 60-GHz Wireless Communications (2009)

This paper presents a new concept of steerable beam antenna composed by a dielectric lens which pivots in front of a single stationary moderate gain feed. The lens not only allows steering mechanically the beam in elevation and full azimuth, but further increases the gain up to 21 dBi. The solution is broadband, including the entire international unlicensed spectrum from 57 GHz to 66 GHz. A fabricated prototype shows the possibility of tilting the beam from - 45deg to + 45deg for all azimuths with gain scan loss below 1.1 dB and radiation efficiency above 95%. The arrangement is very simple, it does not require rotary joints, it is low cost and compact, lens plus feed volume being of the order of 3 times 3 times 3 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> with lens weight less than 10 g.
Chemistry of the Amazon: Biodiversity, Natural Products, and Environmental Issues (1995)

Discusses biodiversity conservation in tropical rainforests. Presents an overview of research on bioactive natural products from the Amazon. Examines current research and investigations of the chemical evolution. Addresses biogeochemistry issues of tropical systems. Provides an overview of environmental issues related to Amazon biodiversity, including the impact of surface mining on the quality of air, water, and soil.