gebhart/patrepeval huggingface dataset:
Characterization of Cells Expressing Lymphatic Marker LYVE-1 in Macaque Large Intestine during Simian Immunodeficiency Virus Infection Identifies A Large Population of Nonvascular LYVE-1 <sup>+</sup> /DC-SIGN <sup>+</sup> Cells (2013)

Abstract LYVE-1 is a marker expressed by lymphatic endothelial cells (LECs) that line the lymphatic endothelium. Through studies designed to examine potential changes in expression of LYVE-1 in cynomolgus macaque colon tissues during the course of simian immunodeficiency virus (SIV) infection, we discovered that LYVE-1 was expressed by heterogenous populations of cells. As revealed by in situ hybridization (ISH), LYVE-1 mRNA levels in colon were decreased in macaques with AIDS compared with acutely infected or uninfected macaques. In the submucosal layer of the colon, approximately half of the LYVE-1-expressing cells co-expressed the dendritic cell (DC) marker, DC-SIGN/CD209, and this percentage did not change appreciably during infection. Subsets of cells expressing LYVE-1 also co-expressed macrophage markers, such as CD68 and the macrophage mannose receptor (MMR)/CD206, in both the colon and lymph nodes. LECs, DCs, and macrophages that co-expressed LYVE-1 were observed in colon and lymph node from uninfected, healthy animals as well as in tissues with SIV-driven inflammation. These findings provide further definition of the phenotypic overlap between LECs and antigen presenting cells, reveal the heterogeneity within the population of cells expressing the lymphatic marker LYVE-1, and show that SIV modulates this population of cells in a mucosal surface across which the virus is acquired.
Variations of the Candidate SEZ6L2 Gene on Chromosome 16p11.2 in Patients with Autism Spectrum Disorders and in Human Populations (2011)

Our results provide an extensive ascertainment of the genetic variability of SEZ6L2 in human populations and do not support a major role for SEZ6L2 sequence variations in the susceptibility to ASD.
Miniature Trace Gas Detector Based on Microfabricated Optical Resonators (2013)

While a variety of techniques exist to monitor trace gases, methods relying on absorption of laser light are the most commonly used in terrestrial applications. Cavity-enhanced absorption techniques typically use high-reflectivity mirrors to form a resonant cavity, inside of which a sample gas can be analyzed. The effective absorption length is augmented by the cavity's high quality factor, or Q, because the light reflects many times between the mirrors. The sensitivity of such mirror-based sensors scales with size, generally making them somewhat bulky in volume. Also, specialized coatings for the high-reflectivity mirrors have limited bandwidth (typically just a few nanometers), and the delicate mirror surfaces can easily be degraded by dust or chemical films. As a highly sensitive and compact alternative, JPL is developing a novel trace gas sensor based on a monolithic optical resonator structure that has been modified such that a gas sample can be directly injected into the cavity. This device concept combines ultra-high Q optical whispering gallery mode resonators (WGMR) with microfabrication technology used in the semiconductor industry. For direct access to the optical mode inside a resonator, material can be precisely milled from its perimeter, creating an open gap within the WGMR. Within this open notch, the full optical mode of the resonator can be accessed. While this modification may limit the obtainable Q, calculations show that the reduction is not significant enough to outweigh its utility for trace gas detection. The notch can be milled from the high- Q crystalline WGMR with a focused ion beam (FIB) instrument with resolution much finer than an optical wavelength, thereby minimizing scattering losses and preserving the optical quality. Initial experimental demonstrations have shown that these opened cavities still support high-Q whispering gallery modes. This technology could provide ultrasensitive detection of a variety of molecular species in an extremely compact and robust package. With this type of modified WGMR, one can inject a gas sample into the open gap, allowing highly sensitive trace molecule detection within a roughly 1-cm volume. Other critical components of the instrument, such as the detector and a semiconductor laser, could be directly packaged with the resonator so as to not significantly increase the size of the device. Besides its low mass, volume, and power consumption, the monolithic design makes these resonators intrinsically robust devices, capable of handling significant temperature excursions, without moving parts to wear out or delicate coatings that can be easily damaged. A sensor could integrate with microfluidics technology for a chip-scale device. It could be mounted to the end of a deployable arm, or inserted into a borehole. Also, a network of individual sensors could be dispersed to monitor conditions over a wide region
Analysis of local carrier modulation in InAs semiconductor nanowire transistors (2007)

The authors have used scanning gate microscopy combined with numerical simulations to analyze local carrier and current modulation effects in InAs semiconductor nanowires grown by metal-organic chemical vapor deposition. Measurements of current flow in the nanowire as a function of probe tip position, at both high and low drain bias, reveal that carrier and current modulation is strongest when the probe tip is near the source and drain nanowire contacts, and decreases at greater tip-contact distances. The measured transconductance is approximately 80% greater near the source contact for high drain bias condition and 120% greater near the drain contact for low drain bias condition, respectively, than at the center of the nanowire. Numerical simulations for different tip positions relative to the metal contact confirm that carrier modulation should be stronger when the tip is closer to the source or drain contact than at the center of the wire, consistent with the experimental measurements.
Spatial time domain reflectometry for monitoring of the hydrological water balance at a lysimeter test site in Thuringia/Germany (2012)

For monitoring of the hydrological water balance in top and subsoil during plant growth accurate knowledge of the spatial and temporal variation of soil water content is essential. In this context, a new full two port spatial time domain reflectometry (Spatial TDR) technique in combination with elongated microwave transmission line sensors were developed for advanced data acquisition and analysis. The technique is tested at a lysimeter station in Thuringia/Germany and compared with neutron moisture meter probes.
A Scalable Grouping Random Key Predistribution Scheme for Large Scale Distributed Sensor Networks (2005)

The security issue in a distributed sensor network (DSN) has been drawing considerable research attention in recent years. Key management, a basic security service, becomes the core design for various security services, such as encryption and authentication. This paper proposes a scalable grouping random key predistribution scheme which divides all nodes into several groups and uses the oneway Junction to generate group-to-group pairwise keys to increase the connectivity of each key and to enlarge the maximum supportable network size.
Squamous Cell Carcinoma of the Penis in a Man with a Human Papilloma Virus 31 Infection (2005)

We report a 51-year-old man with squamous cell carcinoma (SCC) on his penis. He was surgically treated for his phimosis when he was 20 years old. He presented with an indurated nodule on the tip of his penis. The tumor was treated with partial penectomy and standard inguinal lymphadenectomy. Histological examination revealed that the tumor was a well-differentiated type of SCC. A polymerase chain reaction was performed to detect human papilloma virus (HPV) DNA. The result revealed the presence of HPV in the SCC. The results of sequencing analysis showed that the DNA was HPV 31.
The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes. (1992)

Amelogenins, a family of extracellular matrix proteins of the dental enamel, are transiently but abundantly expressed by ameloblasts during tooth development. Amelogenins seem to regulate the formation of crystallites during the secretory stage of enamel development, while they are specifically degraded during tooth-bud maturation. In this paper we report the characterization of the AMGX and AMGY genes on the short arms of the human X and Y chromosomes which encode the amelogenins. Our studies on the expression of the amelogenin genes in male developing tooth buds showed that both the AMGX and AMGY genes are transcriptionally active and encode potentially functional proteins. We have isolated genomic and cDNA clones from both the AMGX and AMGY loci and have studied the sequence organization of these two genes. Reverse transcriptase (RT)PCR amplification of the 5' portion of the amelogenin transcripts revealed several alternatively spliced products. The splicing pattern observed in the Y-derived mRNA varies from that of the X-derived mRNA. The promoter regions from both genes and the predicted amelogenin protein sequences are presented. This information will be useful for studying the molecular basis of X-linked amelogenesis imperfecta, for understanding the evolution and regulation of gene expression on the mammalian sex chromosomes, and for investigating the role of amelogenin genes during tooth development.
The Response of Vocal Fold Fibroblasts and Mesenchymal Stromal Cells to Vibration (2012)

Illumination of cellular changes caused by mechanical forces present within the laryngeal microenvironment may well guide strategies for tissue engineering the vocal fold lamina propria. The purpose of this study was to compare the response of human vocal fold fibroblasts (hVFF) and bone marrow mesenchymal stem cells (BM-MSC) to vibratory stimulus. In order to study these effects, a bioreactor capable of vibrating two cell seeded substrates was developed. The cell seeded substrates contact each other as a result of the sinusoidal frequency, producing a motion similar to the movement of true vocal folds. Utilizing this bioreactor, hVFF and BM-MSC were subjected to 200 Hz vibration and 20% strain for 8 hours. Immunohistochemistry (Ki-67 and TUNEL) was performed to examine cell proliferation and apoptosis respectively, while semi-quantitative RT-PCR was used to assess extracellular matrix related gene expression. HVFF significantly proliferated (p = 0.011) when subjected to 200 Hz vibration and 20% strain, while BM-MSC did not (p = 1.0). A statistically significant increase in apoptosis of BM-MSC (p = 0.0402) was observed under the experimental conditions; however high cell viability (96%) was maintained. HVFF did not have significantly altered apoptosis (p = 0.7849) when subjected to vibration and strain. Semi-quantitative RT-PCR results show no significant differences in expression levels of collagen I (BM-MSC p = 0.1951, hVFF p = v0.3629), fibronectin (BM-MSC p = 0.1951, hVFF p = 0.2513), and TGF-β1 (BM-MSC p = 0.2534, hVFF p = 0.6029) between vibratory and static conditions in either cell type. Finally, smooth muscle actin mRNA was not present in either vibrated or static samples, indicating that no myofibroblast differentiation occurred for either cell type. Together, these results demonstrate that BM-MSC may be a suitable alternative to hVFF for vocal fold tissue engineering. Further investigation into a larger number of gene markers, protein levels, increased number of donors and vibratory conditions are warranted.
<b>Transcriptional regulation of zwf, encoding glucose‐6‐phosphate dehydrogenase, from the cyanobacterium Nostoc punctiforme strain ATCC 29133</b> (1996)

The gene encoding glucose-6-phosphate dehydrogenase (G6PD), zwf, in Nostoc punctiforme strain ATCC 29133 is part of a four-gene operon that also encodes fructose bisphosphatase (fbp), transaldolase (tal) and a gene product termed OpcA, which is contranscribed with zwf and essential for G6PD activity. The effect of exogenous nitrogen and carbon sources on transcription of these genes was investigated. Growth in the presence of ammonium yielded low levels of transcripts encoding all genes of the operon, while growth under nitrogen-fixing conditions resulted in a large increase of transcripts encoding for fbp and zwf-opcA. When cells are grown in the presence of fructose, levels of transcripts encoding tal and zwf-opcA were increased, relative to levels in ammonium-grown cells. These results indicate that this facultatively heterotrophic cyanobacterium can respond to changes in its environment by altering transcription of genes involved in carbon catabolism. Primer extension identified five 5' ends corresponding to the major regulated transcripts which we conclude arise from independent transcriptional start points.
The Dominant Type of Atomic Disorder in α‐Al <sub>2</sub> O <sub>3</sub> (1978)

Comparison of the energy of formation per defect, as deduced from experimental results on α‐Al 2 O 3 doped with donors and acceptors on the basis of various models, with theoretical values calculated by Dienes et al . for various disorder models shows closest correspondence of the exFrimentd values with the smallest theoretical values (obtained for Schottky disorder). This indicates that the theoretical results are reliable and that Schottky disorder is the major type of atomic disorder in α‐Al 2 O 3 . Creep data on Al 2 O 3 :Fe by Hollenberg and Gordon make it possible to determine the enthalpy of Frenkel disorder of Al.
Output feedback adaptive control of non-affine MIMO systems (2002)

We present a direct adaptive control technique for discrete-time multi-input multi-output nonlinear systems with unknown structure but known order and (vector) relative degree. The dynamic control law is based on the implicit function theorem and requires only output feedback. The underlying unknown implicit function can be emulated by any parametrized model, but feedforward neural networks are used here because of the large input dimension of the implicit function.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Effects of galanin on the release of insulin, glucagon and somatostatin from the isolated, perfused dog pancreas (1988)

Galanin is a 29 amino acid peptide which has been found in intrapancreatic nerves. The effects of galanin, adrenergic and cholinergic blockade as well as somatostatin on the hormone release from the isolated perfused dog pancreas were studied. It was found that galanin dose-dependently inhibited insulin (P less than 0.001) and somatostatin (P less than 0.001) but not glucagon secretion at normal glucose levels. The lowest galanin concentration that caused a significant suppression of insulin and somatostatin secretion was 10(-11) and 10(-10) mol/l, respectively. Similar effects were evident during stimulation with 2.5 mmol/l arginine. Galanin (10(-9) mol/l) caused a more pronounced inhibition of insulin and somatostatin secretion at high (10 mmol/l) and normal (5 mmol/l) than at low glucose (1.3 mmol/l). In contrast, suppression of the glucagon secretion was only seen at low glucose (1.3 mmol/l). Perfusion of 10(-6) mol/l of atropine, phentolamine and propranolol had no effect on the galanin-mediated (10(-10) mol/l) inhibition of insulin and somatostatin secretion. Galanin (10(-12)-10(-10) mol/l) and somatostatin (10(-12)-10(-10) mol/l) were equipotent in inhibiting insulin secretion whereas only somatostatin exerted a suppression of the glucagon secretion at normal glucose. Thus, galanin exerts a differential effect on islet hormone secretion and may participate in the hormonal control of insulin, glucagon and somatostatin secretion.
Bedbugs as Vectors for Drug-Resistant Bacteria (2011)

Over the past 10 years in North America and western Europe, a resurgence of bedbugs (Cimex lectularius) has occurred (1).Although the basis for this
Multi-resolution level set image segmentation using wavelets (2011)

Level set methods have been used for image segmentation. Because partial deferential equations are solved to propagate a curve, level-set image segmentation has a slow convergence speed. The objective of this paper is to propose a method that increases the convergence speed. The proposed approach exploits the benefit of multi-resolutional analysis. Wavelet transform is used to decompose the image into different resolutions. The obtained results show a great improvement in terms of speed and accuracy.
Nonlinear Analysis of the Baroreceptor Reflex System (1966)

The regulation of blood pressure by the baroreceptor reflex was examined in anesthetized dogs. The receptor feedback path was broken by surgical intervention, the input (carotid sinus pressure) was controlled by an external servo system, and simultaneous records of input and output (systemic arterial pressure) were obtained. A variety of pressure waveforms were applied to the carotid sinus so that the nonlinear behavior could be explored thoroughly. Most of the input waveforms consisted of relatively small signals about an operating point in the normal blood pressure range. The nonlinear behavior of the reflex was illustrated in a number of ways. Square waves, sinusoids, and short pulses produced asymmetric arterial pressure waveforms. An overshoot in the arterial pressure always followed the rising edge of the input square wave, but was generally absent following the negative-going part of the square wave. Either positive or negative pulses caused a transient drop in arterial pressure. The sinusoidal response was often distorted, with the falling portion of the output waveform steeper than the rising portion. The system behaved as a rectifier, or envelope-detector, as illustrated by 1) the decrease in mean arterial pressure when either the amplitude or the frequency of a sinusoidal input was increased and 2) the appearance in the arterial pressure waveform of a component correlated with the envelope of a modulated carrier. Another nonlinear phenomenon was the decrease in low-frequency sinusoidal gain caused by the addition of a high-frequency sinusoid to the sinus pressure waveform. This behavior indicates that if closed loop behavior in the intact animal is to be predicted from the open loop sinewave response, the effects of the cardiac pressure pulse must be considered. A model was constructed from standard electronic components to simulate the input-output behavior of the baroreceptor reflex. The model was able to simulate the response to high- and low-frequency sinusoids and to reproduce the essential features of the square-wave and pulse responses. On this basis the model was considered adequate for simulating the performance of the baroreceptor reflex in certain open loop and closed loop situations.
Sequential Point Estimation Procedures for the Generalized Life Distributions (2001)

SYNOPTIC ABSTRACTSequential procedures are developed for the point estimation of the parameter of the generalized life distributions under (i) squared-error loss function plus linear cost of sampling and (ii) squared-error loss function plus log-cost function. Second-order approximations are obtained for the risk and theoretical justifications to some of the numerical findings of Starr and Woodroofe (1972) is given. ‘Improved’ estimators are proposed and their dominance over the usual estimators is established.
1,4-Dimethoxy-5-methyl-6-tetralone and 1,4-Dimethoxy-5,5-dimethyl-6-tetralone (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,4-Dimethoxy-5-methyl-6-tetralone and 1,4-Dimethoxy-5,5-dimethyl-6-tetraloneT. R. Lewis, William B. Dickinson, and S. ArcherCite this: J. Am. Chem. Soc. 1952, 74, 21, 5321–5324Publication Date (Print):November 1, 1952Publication History Published online1 May 2002Published inissue 1 November 1952https://pubs.acs.org/doi/10.1021/ja01141a029https://doi.org/10.1021/ja01141a029research-articleACS PublicationsRequest reuse permissionsArticle Views188Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Die Acetylierung der Baumwollcellulose (1911)

Paraffingatsch einer Redestillation, so zerfillt es in Fraktionen von verschiedenen Eigenschaften.Rei solcher Redestillation (unter 10 cm Vakuum und mit sehr kleinen Mengen Wasserdampf) eines Rohparaffinkuchens vom F'. 49" erhielt G u i s e 1 i n 11 ca.gleich grol3e Fraktionen, deren Schmelzpunkt von 40 bis auf 58" stieg; der Ruckstand (etwa 6,5% des ganzen) hatte einen F. 61" und nach Reinigung mit Schwefelsaure 65", war amorph und Ozokerit ahnlich.Der Schmelzpunkt des Rohparaffins kann auch ohne Redestillation, durch energische Behandlung mit groBen Mengen Schwefelsaure (bei 80") um mehrere Grade erhoht werden.J. T a n n e und G. O b e r l i i n d e r 7 1 ) schlagen vor, paraffinhaltige Erdolruckstiinde in mit &lo% Eisessig vermischtem Benzin aufzulosen und daraus das Paraffin ausfrieren zu lassen; in Gegenwart von Eisessig soll das Paraffin nicht amorph, sondern als feinkorniger Brei sich ausscheiden.Es erscheint sehr zweifelhaft, ob die Verwendung eines so teuren Stoffes,
HPKS: High Performance Kubernetes Scheduling for Dynamic Blockchain Workloads in Cloud Computing (2021)

Emerging blockchain technologies have been increasingly popular and reforming our daily lives. Fusing blockchain technology with existing cloud systems has a great benefits in both improving the functionality/performance and guaranteeing the security/privacy. However, most existing commercial systems fail to address the characteristics of PoS blockchain applications in the cloud. In real-world scenarios, jobs/pods may arrive and leave due to the workload changes. Traditionally, the selection process is based on the state of the workers, e.g., resource availability and specifications of pods. In this paper, we not only provide an optimal solution for offline workloads management which minimizes the number of used workers to reduce the total computational resource demand, but also propose a high performance Kubernetes scheduling scheme HPKS, which maximizes the utilization of workers. Specifically, extensive experiments based on real PoS blockchain applications shows that HPKS reduces the average worker nodes usage by 13.0%. Additionally, the overall increase of Makespan using HPKS is less than 3% when compared to the default scheduler available in Kubernetes.
Synthesis of spatial filters with Chebyshev characteristics (1976)

A spatial filtering technique using layered dielectrics for the reduction of antenna grating lobes or sidelobes is introduced and developed. The filters are used as a radome at the array face, and can be synthesized to have Chebyshev behavior in the spatial domain. Data are given for the design of two, three, and four layer filters with various spatial passband ranges and ripple levels.