gebhart/patrepeval huggingface dataset:
High-silica Fluosilicic Acids: Specific Reactions and the Equilibrium with Silica (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHigh-silica Fluosilicic Acids: Specific Reactions and the Equilibrium with SilicaS. Milton ThomsenCite this: J. Am. Chem. Soc. 1952, 74, 7, 1690–1693Publication Date (Print):April 1, 1952Publication History Published online1 May 2002Published inissue 1 April 1952https://pubs.acs.org/doi/10.1021/ja01127a023https://doi.org/10.1021/ja01127a023research-articleACS PublicationsRequest reuse permissionsArticle Views243Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fractionation of BSA and lysozyme using ultrafiltration: Effect of gas sparging (1998)

Abstract Fractionation of proteins by ultrafiltration is an interesting challenge. With a particular membrane, the protein – protein and protein – membrane interactions largely decide which protein passes through and which is retained. System hydrodynamics also affects protein fractionation as the transmission behavior of a protein is altered by concentration polarization. Therefore, disruption of the concentration polarization layer would help to maintain the native selectivity of the membrane and hence aid in protein fractionation. An attempt is made to use gas sparging, a technique proven effective in controlling concentration polarization to enhance the selectivity of separation of BSA (MW 67,000) and lysozyme (MW 14,100). The effects of gas flow rate, liquid flow rate and feed concentration on the selectivity of fractionation are examined. Gas sparging enhances protein fractionation; under suitable solution conditions, nearly complete separation of BSA and lysozyme was achieved with gas sparged ultrafiltration. The permeate flux was also increased by gas sparing. The mechanism of enhancement is explained in terms of disruption of the concentration polarization layer and enhanced mass transfer due to bubble‐induced secondary flow.
Lateral dimerization is required for the homophilic binding activity of C-cadherin. (1996)

Regulation of cadherin-mediated adhesion can occur rapidly at the cell surface. To understand the mechanism underlying cadherin regulation, it is essential to elucidate the homophilic binding mechanism that underlies all cadherin-mediated functions. Therefore, we have investigated the structural and functional properties of the extracellular segment of Xenopus C-cadherin using a purified, recombinant protein (CEC 1-5). CEC 1-5 supported adhesion of CHO cells expressing C-cadherin. The extracellular segment was also capable of mediating aggregation of microspheres. Chemical cross-linking and gel filtration revealed that CEC 1-5 formed dimers in the presence as well as absence of calcium. Analysis of the functional activity of purified dimers and monomers demonstrated that dimers retained substantially greater homophilic binding activity than monomers. These results demonstrate that lateral dimerization is necessary for homophilic binding between cadherin extracellular segments and suggest multiple potential mechanisms for the regulation of cadherin activity. Since the extracellular segment alone possessed significant homophilic binding activity, the adhesive activity of the extracellular segment in a cellular context was analyzed. The adhesion of CHO cells expressing a truncated version of C-cadherin lacking the cytoplasmic tail was compared to cells expressing the wild-type C-cadherin using a laminar flow assay on substrates coated with CEC 1-5. CHO cells expressing the truncated C-cadherin were able to attach to CEC 1-5 and to resist detachment by low shear forces, demonstrating that tailless C-cadherin can mediate basic, weak adhesion of CHO cells. However, cells expressing the truncated C-cadherin did not exhibit the complete adhesive activity of cells expressing wild-type C-cadherin. Cells expressing wild-type C-cadherin remained attached to CEC 1-5 at high shear forces, while cells expressing the tailless C-cadherin did not adhere well at high shear forces. These results suggest that there may be two states of cadherin-mediated adhesion. The first, relatively weak state can be mediated through interactions between the extracellular segments alone. The second strong adhesive state is critically dependent on the cytoplasmic tail.
Ultra-wideband electronically tunable pulse generators (2004)

We report on the development of new low-cost, compact ultra-wideband microstrip pulse generators capable of varying the pulse duration electronically. These electronically tunable pulse generators generate an initial step function using a step recovery diode, which is then converted into pulses of various durations by alternately switching on one of the switches, realized by PIN diode or MESFET, spatially located along a short-circuited transmission line. Representative pulse-duration variations from 300 to 800 ps have been demonstrated experimentally and theoretically. Good symmetry and low distortion have been achieved for the pulses. Measured results also confirm the simulations.
Estimation of maximum currents in MOS IC logic circuits (1990)

The authors deal with estimating currents in nMOS/CMOS IC logic circuits at three levels of hierarchies: gate level, macro level, and power/ground distribution level. Models are developed for estimating currents in a macro-cell (macro) in response to input excitations. Algorithms are developed to estimate the maximum current requirement for a macro and to identify the input excitation at which the maximum current occurs. The macro currents are used to estimate the maximum currents in the segments of power (ground) distribution systems. Some of the algorithms provide tradeoff between runtime and quality of solutions. Experimental results are included.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Gene–gene interaction of erythropoietin gene polymorphisms and diabetic retinopathy in Chinese Han (2016)

The aim of this study was to investigate the association of three single nucleotide polymorphisms in the erythropoietin gene polymorphisms with diabetic retinopathy and additional role of gene-gene interaction on diabetic retinopathy risk. A total of 1193 patients (579 men, 614 women) with type 2 diabetes mellitus were selected, including 397 diabetic retinopathy patients and 796 controls (type 2 diabetes mellitus patients without diabetic retinopathy); the mean age of all participants was 56.7 ± 13.9 years. Three single nucleotide polymorphisms were selected: rs507392, rs1617640, and rs551238. The t-test was used for comparison of erythropoietin protein level erythropoietin levels in patients having different erythropoietin genotypes. Logistic regression model was used to examine the association between three single nucleotide polymorphisms and diabetic retinopathy. Odds ratio (OR) and 95% confident interval (95% CI) were calculated. Generalized multifactor dimensionality reduction was employed to analyze the impact of interaction among three single nucleotide polymorphisms on CVD risk. After covariates adjustment, the carriers of homozygous mutant of three single nucleotide polymorphisms have higher diabetic retinopathy risk than those with wild-type homozygotes, OR (95% CI) were 2.04 (1.12-2.35), 1.87 (1.10-2.41) and 1.15 (1.06-1.76), respectively. Generalized multifactor dimensionality reduction model indicated a significant three-locus model (p = 0.0010) involving rs507392, rs1617640, and rs551238. Overall, the three-locus models had a cross-validation consistency of 10 of 10, and had the testing accuracy of 60.72%. Subjects with TC or CC-TG or GG-AC or CC genotype have the highest diabetic retinopathy risk. In conclusion, our results support an important association of rs507392, rs1617640 and rs551238 minor allele of erythropoietin with increased diabetic retinopathy risk, and additional interaction among three single nucleotide polymorphisms.
Microparticles of all shapes and chemistries (2006)

ADVERTISEMENT RETURN TO ISSUEPREVLAB FABNEXTMicroparticles of all shapes and chemistriesRajendrani MukhopadhyayCite this: Anal. Chem. 2006, 78, 13, 4247Publication Date (Web):July 1, 2006Publication History Published online1 July 2006Published inissue 1 July 2006https://pubs.acs.org/doi/10.1021/ac069423vhttps://doi.org/10.1021/ac069423vnewsACS Publications. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views190Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (60 KB) Get e-Alertsclose SUBJECTS:Microparticles Get e-Alerts
Word synchronization and digital signal processing for a high capacity mobile telecommunications system (1977)

In the BTL developed High Capacity Mobile Telecommunications System a 10K bit/sec digital signaling system is used to provide information needed in the various stages of call set-up and control. This paper focuses particular attention on the word-sync reliability problem for data-burst signaling as used to provide channel designations for cell-to-cell handoffs. It is shown that a simple quasi-static model of the Rayleigh fading carrier can be used to predict miss and false response rates of a Barker framing sequence. Also, it is shown that by appropriately processing word-sync information, three orders improvement in the false response rates can be routinely achieved.
Al on GaAs(110) interface: Possibility of adatom cluster formation (1981)

A reexamination of the experimental data and previous electronic-structure calculations on the prototype Schottky system Al/GaAs(110), together with new calculations, indicates that at low coverages and temperatures neither a covalent bond nor a metallic bond is likely to be formed between Al and the substrate. Instead, the predominant species is likely to be Al clusters which interact only weakly and largely nondirectionally with the substrate. In contrast with all previous theoretical models which assume an epitaxially ordered array of chemisorption bonds even at submonolayer coverage, it then appears that the formation of a Schottky barrier as well as other physical and chemical characteristics of the interface (e.g., core level and exciton shifts, valence-band photoemission spectra, gap states, surface atomic relaxation) are not explainable in terms of strong and ordered chemisorption bonds. This weakly interacting cluster model leads to several interesting predictions regarding the atomic structure and spectroscopy of this metal-semiconductor interface at the initial stages of its formation. The properties of the interface at higher temperatures (i.e., after annealing) are discussed in terms of an Al-Ga exchange reaction.
LI-F Antibiotics, a Family of Antifungal Cyclic Depsipeptides Produced by Bacillus polymyxa L-1129 (2000)

Twelve antifungal depsipeptide antibiotics named as LI-F03a, LI-F03b, LI-F04a, LI-F04b, LI-F05a, LI-F05b, LI-F06a,
MS-CapsNet: A Novel Multi-Scale Capsule Network (2018)

Capsule network is a novel architecture to encode the properties and spatial relationships of the feature in an image, which shows encouraging results on image classification. However, the original capsule network is not suitable for some classification tasks, where the target objects are complex internal representations. Hence, we propose a multi-scale capsule network that is more robust and efficient for feature representation in image classification. The proposed multi-scale capsule network consists of two stages. In the first stage, structural and semantic information are obtained by multi-scale feature extraction. In the second stage, the hierarchy of features is encoded to multi-dimensional primary capsules. Moreover, we propose an improved dropout to enhance the robustness of the capsule network. Experimental results show that our method has a competitive performance on FashionMNIST and CIFAR10 datasets.
Measurements of cutter forces and cutter temperature of boring machine in Äspö Hard Rock Laboratory (2001)

This report presents both the testing methods used and the testing results obtained for cutter forces and cutter temperature during field boring in Äspö Hard Rock Laboratory. In order to estimate the strains induced by cutter forces in the cutter shaft and choose proper transducers, first a numerical simulation was performed. The simulation results indicated that the cutter forces should be measurable by ordinary strain gauges. Furthermore, an independent three-direction loading system for laboratory calibration was set up to solve force-coupling problems appearing in field measurements. By means of the established measuring system, which was proved successful in the laboratory, the normal forces, tangential forces, and side forces of two button cutters in the boring machine were measured in the field. In addition, the temperature in the shaft of the front cutter was measured. After the measurements of the cutter forces and cutter temperature, rock core samples were taken from the bottom and the wall of the testing borehole. Then the samples were cut, polished, and examined by means of the Scanning Electron Microscope (SEM). After that, the lengths of major cracks induced by the cutters in the rock samples were measured, and an approximate relationship between the length of the medium cracks and the relevant cutter forces was obtained. This relationship was compared with the theoretical relationship established before. Finally, according to the measured results, the cracked zones around the borehole were described. The results show that: (1) there are two kinds of cracked zones: one in the borehole wall and the other in the bottom of the borehole. The depth of the cracked zone in the borehole bottom is much larger than that in the borehole wall because the maximum normal force of the front cutter is always much larger than that of the gauge cutter. (2) Each cracked zone includes a densely cracked zone and all the longest medium cracks caused by mechanical boring. (3) According to the measurements for four rock core samples, the maximum depth of the cracked zone in the borehole bottom is 27.1 mm, and the maximum depth of the densely cracked zone is 2.5-3 mm.
Aquaplast Thermoplastic (Opti‐Mold) (1994)

Aquaplast thermoplastic (Opti-Mold), a unique moldable "tie-down" dressing, can be heated, shaped, and sutured in place over full-thickness skin grafts. It allows for excellent uniform pressure over a skin graft while also allowing for drainage from the graft bed, and is particularly useful for the contoured surfaces of the nose and ears.
A differential geometric approach to discrete-coefficient filter design (2009)

This paper is concerned with the problem of computing a discrete-coefficient approximation to a digital filter. In contrast to earlier works that have approached this problem using standard combinatorial optimization tools, we take a geometric approach. We define a Riemannian manifold, arising from the difference in frequency response between the two systems of interest, on which we design efficient algorithms for sampling and approximation. This additional structure enables us to tame the computational complexity of the native combinatorial optimization problem. We illustrate the benefits of this approach with design examples involving IIR and FIR filters.
Inhibition of Integrin-mediated Cell Adhesion but Not Directional Cell Migration Requires Catalytic Activity of EphB3 Receptor Tyrosine Kinase (2004)

Genetic studies have shown that Eph receptor tyrosine kinases have both kinase-dependent and kinase-independent functions through incompletely understood mechanisms. We report here that ephrin-B1 stimulation of endogenous EphB kinases in LS174T colorectal epithelial cells inhibited integrin-mediated adhesion and HGF/SF-induced directional cell migration. Using 293 cells stably transfected with wild type (WT)- or kinase-deficient (KD-EphB3), we found that inhibition of integrin-mediated cell adhesion and induction of cell rounding was kinase-dependent. Unexpectedly, in two independent assays, both KD- and WT-EphB3 significantly inhibited directional cell migration. Upon ephrin-B1 stimulation, the activities of Rac1 and Cdc42 were reduced in both WT- and KD-EphB3-expressing cells that were induced to migrate. Pharmacological evidence demonstrates that a relative increase in RhoA signaling as a result of decreased Rac1/Cdc42 activities contributes to the inhibitory effects. Furthermore, EphB3-mediated inhibitory effect on cell adhesion but not migration was abolished by the integrin activating antibodies, suggesting that the inhibition of cell migration is not because of down-regulation of integrin function. These results uncover a differential requirement for EphB3 catalytic activity in the regulation of cell adhesion and migration, and suggest that while catalytic activity of EphB3 is required for inhibition of integrin-mediated cell adhesion, a distinct signaling pathway to Rho GTPases shared by WT- and KD-EphB3 receptor mediates inhibition of directional cell migration.
Glyceraldehyde-3-phosphate dehydrogenase: Nuclear translocation participates in neuronal and nonneuronal cell death (1997)

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) protein levels increase in particulate fractions in association with cell death in HEK293 cells, S49 cells, primary thymocytes, PC12 cells, and primary cerebral cortical neuronal cultures. Subcellular fractionation and immunocytochemistry reveal that this increase primarily reflects nuclear translocation. Nuclear GAPDH is tightly bound, resisting extraction by DNase or salt treatment. Treating primary thymocytes, PC12 cells, and primary cortical neurons with antisense but not sense oligonucleotides to GAPDH prevents cell death. Because cell-death-associated nuclear translocation of GAPDH and antisense protection occur in multiple neuronal and nonneuronal systems, we propose that GAPDH is a general mediator of cell death and uses nuclear translocation as a signaling mechanism.
A Sponge Matrix Method for Tissue Culture. Formation of Organized Aggregates of Cells <italic>in Vitro</italic><xref ref-type="fn" rid="fn1"><sup>2</sup></xref> (1951)

Journal Article A Sponge Matrix Method for Tissue Culture. Formation of Organized Aggregates of Cells in Vitro Get access Joseph Leighton Joseph Leighton Pathology Section, National Cancer Institute4Bethesda, Md. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 12, Issue 3, December 1951, Pages 545–561, https://doi.org/10.1093/jnci/12.3.545 Published: 01 December 1951 Article history Received: 29 August 1951 Published: 01 December 1951
Synapse Formation Between Two Clonal Cell Lines (1977)

Clonal neuroblastoma x glioma hybrid cells frequently formed synapses with clonal mouse striated muscle cells. Clonal myotubes were similar to cultured mouse embryo myotubes with respect to acetylcholine sensitivity and other membrane properties examined. However, acetylcholine sensitivity measurements indicate that acetylcholine receptors of clonal myotubes are distributed more uniformly over the cell surface than the receptors of cultured mouse embryo myotubes.
Remote monitoring and medical devices control in eHealth (2016)

This paper presents a solution that improves remote monitoring and real-time control of medical devices in eHealth, and provides better user experience and deployment simplicity. Our approach builds a unified, scalable, secure and real-time platform making use of IoT Gateways to remotely monitor patients and manage/control diverse types of sensors and IoT medical devices. WebRTC is used as a key architectural component to enable interactive communication between smart medical spaces (e.g., clinics, patients' homes) and remote users (e.g., health/wellness services, physicians, medical staff). We also demonstrate the need for an Edge Cloud to save on network bandwidth usage especially for video traffic for remote monitoring and to ensure real-time control of medical devices. We implemented a Proof of Concept (PoC) to test our solution. The performance results obtained measure the utility of the proposed approach and its effectiveness in real-time eHealth services.
Room-temperature dipole ferromagnetism in linear-self-assembling mesoscopic Fe particle arrays (1997)

Quasi-one-dimensional, nanometer-diameter Fe particle arrays have been prepared by self-organized shadow growth on regularly faceted NaCl (110) surfaces. A room-temperature dipole-ferromagnetic phase was observed for linear arrays of Fe particles with radii larger than 2.5 nm. Surface magneto-optic Kerr magnetization curves indicate easy-axis alignment along the rows of particles. Remanence and coercivity were strong functions of particle diameter and linear island density. Experimental results are compared with Monte Carlo micromagnetics calculations, which, with no free parameters, reproduce the experimental observations.
Fabrication of titanium implant-retained restorations with nontraditional machining techniques. (1995)

Traditional laboratory techniques are being supplemented by modern precision technologies to solve complex restorative problems. Electrical discharge machining combined with laser scanning and computer aided design-computer aided manufacturing can create very precise restorations without the lost wax method. A laser scanner is used to create a three-dimensional polyline data model that can then be converted into a stereolithography file format for output to a stereolithography apparatus or other rapid prototyping device. A stereolithography-generated model is used to create an electric discharge machining electrode via copper electroforming. This electrode is used to machine dental restorations from an ingot of titanium, bypassing the conventional lost wax casting process. Retaining screw access holes are machined using conventional drilling procedures, but could be accomplished with electric discharge machining if desired. Other rapid prototyping technologies are briefly discussed.