gebhart/patrepeval huggingface dataset:
Innovative Multi-Site Photoplethysmography Analysis for Quantifying Pulse Amplitude and Timing Variability Characteristics in Peripheral Arterial Disease (2018)

Photoplethysmography (PPG) is a simple-to-perform vascular optics measurement technique that can detect blood volume changes in the microvascular bed of tissue. Beat-to-beat analysis of the PPG waveform enables the study of the variability of pulse features, such as the amplitude and the pulse arrival time (PAT), and when quantified in the time and frequency domains, has considerable potential to shed light on perfusion changes associated with peripheral arterial disease (PAD). In this pilot study, innovative multi-site bilateral finger and toe PPG recordings from 43 healthy control subjects and 31 PAD subjects were compared (recordings each at least five minutes, collected in a warm temperature-controlled room). Beat-to-beat normalized amplitude variability and PAT variability were then quantified in the time-domain using two simple statistical measures and in the frequency-domain bilaterally using magnitude squared coherence (MSC). Significantly reduced normalized amplitude variability (healthy control 0.0384 (interquartile range 0.0217⁻0.0744) vs. PAD 0.0160 (0.0080⁻0.0338) (<i>p</i> < 0.0001)) and significantly increased PAT variability (healthy control 0.0063 (0.0052⁻0.0086) vs. PAD 0.0093 (0.0078⁻0.0144) (<i>p</i> < 0.0001)) was demonstrated for the toe site in PAD using the time-domain analysis. Frequency-domain analysis demonstrated significantly lower MSC values across a range of frequency bands for PAD patients. These changes suggest a loss of right-to-left body side coherence and cardiovascular control in PAD. This study has also demonstrated the feasibility of using these measurement and analysis methods in studies investigating multi-site PPG variability for a wide range of cardiac and vascular patient groups.
<sup>225</sup>Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer (2016)

Targeted α-therapy with <sup>225</sup>Ac-PSMA-617, although still experimental, obviously has strong potential to significantly benefit advanced-stage prostate cancer patients.
BlockPro (2018)

Data provenance and data integrity are among the key concerns in IoT based environments such as smart cities, smart grids, and vehicular networks etc. Many IoT devices suffer from both impersonation and data tampering attacks due to their architectural and computational limitations, which are unable to provide adequate level of security. This paper aims to provide and enforce data provenance and data integrity in IoT environments by using Physical Unclonable Functions (PUFs) and Ethereum, a blockchain variant with smart contracts. PUFs provide unique hardware fingerprints to establish data provenance while Ethereum provides a decentralized digital ledger which is able to withstand data tampering attacks.
VANTED v2: a framework for systems biology applications (2012)

VANTED is a stand-alone framework which supports scientists during the data analysis and interpretation phase. It is available as a Java open source tool from http://www.vanted.org.
Efficient 3-D simulation of complex structures (1991)

A 3-D general-purpose device simulator is presented, and issues related to its geometrical flexibility and computational efficiency are discussed. Triangular-based prismatic elements are used as building blocks for the discretization of device equations, providing a reasonable tradeoff between simplicity and geometrical flexibility. Suitable numerical techniques, including a 'local-solution' algorithm, have been implemented in order to improve the computational efficiency of the code. A general treatment has been devised to handle floating-gate devices, which allows the program to cope with complex structures, such as a dual EPROM structure. Three-dimensional and two-dimensional simulation results are compared.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Procedure cloning: a transformation for improved system-level functional partitioning (1997)

Functional partitioning assigns the functions of a system's program-like specification among system components, such as standard-software and custom-hardware processors. We introduce a new transformation, called procedure cloning, that significantly improves functional partitioning results. The transformation creates a clone of a procedure for sole use by a particular procedure caller, so the clone can be assigned to the caller's processor, which in turn improves performance through reduced communication. We define several cloning heuristics that seek to clone the minimum number of procedures, a goal necessary to obtain the best improvements. We highlight experiments comparing our cloning heuristics and showing partition improvements with cloning.
Validation of machining operations by a Virtual Numerical Controller Kernel based simulation (2020)

A Digital Production Twin of a machine tool can be accomplished with the Common Simulation Engine (CSE) based on a Virtual Numerical Controller Kernel (VNCK) of a corresponding control of a machine tool. The main advantage of the VNCK simulation lies in the detection of syntax errors, which cannot be found via a 3D-simulation. As a result, the Numerical Control (NC) code can be regarded as validated except the used machining data. In this paper, a method is presented which can validate the complete NC code before it is tested on the real machine tool.
Long-term venous access. (1984)

The aim of this review is to outline the indications and provide a historical perspective of its development. The current complications are emphasized with the hope that greater caution and vigilance will lead to a reduction in their frequency. Finally, details of several techniques are described for gaining long-term venous access for critically ill or injured patients.
Stepwise Synthesis of Substituted Oligo(phenylenevinylene) via an Orthogonal Approach (1997)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTStepwise Synthesis of Substituted Oligo(phenylenevinylene) via an Orthogonal ApproachTodd Maddux, Wenjie Li, and Luping YuView Author Information Department of Chemistry and The James Frank Institute, The University of Chicago 5725 South Ellis Avenue, Chicago, Illinois 60637 Cite this: J. Am. Chem. Soc. 1997, 119, 4, 844–845Publication Date (Web):January 29, 1997Publication History Received29 August 1996Published online29 January 1997Published inissue 1 January 1997https://pubs.acs.org/doi/10.1021/ja9629928https://doi.org/10.1021/ja9629928rapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views685Altmetric-Citations122LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Fluorescence,Molecular properties,Molecules,Monomers,Oligomers Get e-Alerts
Improved efficiency in the parametric transmitting array (1975)

It is shown that the efficiency of the parametric transmitting array may be improved over that obtained where two equal amplitude-frequency components are employed in the primary wave. Through suitable periodic shaping of the envelope of the primary wave, available improvements in the output at the ’’difference’’ frequency of between 2.1 and 6.0 dB are possible in principle. The degree of available improvement depends upon whether the transmitter is peak power or average power limited and whether finite-amplitude attenuation of the primary wave is significant. It is proposed that the on–off modulation of a single-frequency carrier provides a simple, practical method through which near optimum efficiencies may be obtained under most circumstances. A bandwidth greater than the ’’difference’’ frequency is required at the transducer in order to achieve this improvement. Subject Classification: 25.35; 30.75.
Optimization of the spatial properties of illumination for improved lithographic response (1993)

Using computer simulations of the lithographic process, the effects of illuminator modifications are studied. Both symmetric (e.g., annular) and asymmetric (e.g., quadrupole) illumination are discussed and annular illumination is examined in detail. The most significant trade-off in the use of these illuminators is that by optimizing the illumination for one feature size and type, other features may be degraded. Mask linearity also worsens and ceases to be a reliable metric for lithographic quality. The benefit is improved depth-of-focus at the feature size for which the illumination was optimized. These trade-offs are studied in detail and general recommendations for a design approach for the use of different illumination schemes are made.
Efficiencies of Four Versions of the AMPLICOR HIV-1 MONITOR Test for Quantification of Different Subtypes of Human Immunodeficiency Virus Type 1 (1999)

Three versions of a commercial human immunodeficiency virus (HIV) type 1 (HIV-1) load test (the AMPLICOR HIV-1 MONITOR Test versions 1. 0, 1.0+, and 1.5; Roche Diagnostics, Branchburg, N.J.) were evaluated for their ability to detect and quantify HIV-1 RNA of different genetic subtypes. Plasma samples from 96 patients infected with various subtypes of HIV-1 (55 patients infected with subtype A, 9 with subtype B, 21 with subtype C, 2 with subtype D, 7 with subtype E, and 2 with subtype G) and cultured virus from 29 HIV-1 reference strains (3 of subtype A, 6 of subtype B, 5 of subtype C, 3 of subtype D, 8 of subtype E, 3 of subtype F, and 1 of subtype G) were tested. Detection of subtypes A and E was significantly improved with versions 1.0+ and 1.5 compared to that with version 1. 0, whereas detection of subtypes B, C, D, and G was equivalent with the three versions. Versions 1.0, 1.0+, and 1.5 detected 65, 98, and 100% of the subtype A-infected samples from patients, respectively, and 71, 100, and 100% of the subtype E-infected samples from patients, respectively. Version 1.5 yielded a significant increase in viral load for samples infected with subtypes A and E (greater than 1 log10 HIV RNA copies/ml). For samples infected with subtype B, C, and D and tested with version 1.5, only a slight increase in viral load was observed (<0.5 log10). We also evaluated a prototype automated version of the test that uses the same PCR primers as version 1.5. The results with the prototype automated test were highly correlated with those of the version 1.5 test for all subtypes, but were lower overall. The AMPLICOR HIV-1 MONITOR Test, version 1.5, yielded accurate measurement of the HIV load for all HIV-1 subtypes tested, which should allow the test to be used to assess disease prognosis and response to antiretroviral treatment in patients infected with a group M HIV-1 subtype.
Toward a reliable, secure and fault tolerant smart grid state estimation in the cloud (2013)

The collection and prompt analysis of synchrophasor measurements is a key step towards enabling the future smart power grid, in which grid management applications would be deployed to monitor and react intelligently to changing conditions. The potential exists to slash inefficiencies and to adaptively reconfigure the grid to take better advantage of renewables, coordinate and share reactive power, and to reduce the risk of catastrophic large-scale outages. However, to realize this potential, a number of technical challenges must be overcome. We describe a continuously active, timely monitoring framework that we have created, architected to support a wide range of grid-control applications in a standard manner designed to leverage cloud computing. Cloud computing systems bring significant advantages, including an elastic, highly available and cost-effective compute infrastructure well-suited for this application. We believe that by showing how challenges of reliability, timeliness, and security can be addressed while leveraging cloud standards, our work opens the door for wider exploitation of the cloud by the smart grid community. This paper characterizes a PMU-based state-estimation application, explains how the desired system maps to a cloud architecture, identifies limitations in the standard cloud infrastructure relative to the needs of this use-case, and then shows how we adapt the basic cloud platform options with sophisticated technologies of our own to achieve the required levels of usability, fault tolerance, and parallelism.
Catalysis by palladium complexes: new prospects in amination of aryl and hetaryl chlorides (2008)

The main achievements in the chemistry of palladium-catalysed amination of chloroarenes are discussed. The general mechanism of the Buchwald–Hartwig reaction and the main types of catalytic systems used for the amination of aryl and hetaryl chlorides are considered.
Timing Electronics and Fast Timing Methods with Scintillation Detectors (1985)

Time spectroscopy involves the measurement of the time relationship between two events. This paper reviews time pick-off techniques, practival time-pickoff circuits, and timing with scintillation detectors. A detailed comparison is made between leading-edge timing and constant-fraction timing. Typical timing resolution results are given for 60Co.
Detection of enterotoxigenic Bacteroides fragilis by PCR (1997)

Strains of enterotoxigenic Bacteroides fragilis (ETBF) are associated with diarrhea in young farm animals and, at least in particular settings, in children. Enterotoxin production by ETBF is currently detected by a tissue culture assay with HT-29 cells. We have developed a PCR assay based on the detection of the enterotoxin gene to identify ETBF in culture and in stool samples. Overall, 113 bacterial strains were examined, including 3 B. fragilis reference strains, 75 B. fragilis isolates (comprising 40 ETBF isolates), 20 Bacteroides spp. other than B. fragilis, and 15 strains belonging to other genera. Complete agreement was found between the results of the tissue culture assay and those of the PCR for our strains. PCR was also used to detect ETBF directly in fecal samples. Stools from two healthy volunteers were spiked with known numbers of ETBF and were processed by three different methods. A culture method, which required inoculation of the stools on selective plates and the collection of the whole bacterial growth ("sweeps"), was found to be the most sensitive. PCR performed with the plate sweeps yielded amplification products with a detection limit of 10(5) to 10(4) CFU/g of feces. By this method 18 samples of diarrheic stools (10 positive and 8 negative for ETBF) were examined. The results of the PCR were in accordance with the culture results in all cases. The proposed PCR assay represents a diagnostic tool for the rapid identification of ETBF in culture as well as in fecal samples.
Brain imaging in the context of food perception and eating (2012)

Overall, a complex picture arises from brain-imaging findings, because a multitude of factors influence human food choice. Although several key mechanisms have been identified, there is no comprehensive model that is able to explain the behavioral observations to date. Especially a careful characterization of patients according to genotypes and phenotypes could help to better understand the current and future findings in neuroimaging studies.
An User Task and User Requirement Based Approach to Interaction Design Patterns (2006)

Interaction Design Patterns are approached as an instrument to support the mapping of generic user tasks and user requirements with proven interaction design solutions. Generic user tasks and user requirements need to be valid across different applications within a specified context of use. User tasks and user requirements are integrated into interaction design patterns. Using an example from interactive television applications an user task and user requirement based interaction design pattern is presented.
Low Electron Effective Masses and Energy Gap in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Cd</mml:mi></mml:mrow><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Hg</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>−</mml:mo><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mi mathvariant="normal">Te</mml:mi></mml:math> (1961)

Received 10 November 1961DOI:https://doi.org/10.1103/PhysRevLett.7.403©1961 American Physical Society
Investigation of the factor VIII intron 22 repeated region (int22h) and the associated inversion junctions (1995)

A region of intron 22 of the factor VIII gene, which contains factor VIII-associated gene A (F8A), is repeated twice more nearer the Xq telomere. It has been proposed that intrachromosomal homologous recombination occurs between the intron 22 repeat and either of the two extragenic copies, resulting in the recurrent inversions that cause almost half of all cases of severe haemophilia A. We have precisely defined the repeated region as 9.5 kb of DNA which we have termed int22h (intron 22 homologous region). The junctions of the inversions examined were shown to represent precise exchanges between the int22h repeats, thus providing conclusive evidence for homologous recombination. The three copies of int22h were compared along 8 kb of their length, using chemical mismatch analysis, and found to be 99.9% similar. The presence of such long, almost identical inverted repeats near the Xq telomere could account for the high frequency at which the inversions occur.
The Diversity of Volume Regulatory Mechanisms (1998)

Mammalian cells utilize a wide variety of cell volume regulatory mechanisms. For rapid adjustment of cell volume cells release or accumulate ions through respective channels and transport systems across the cell membrane. The most widely used mechanisms of cell volume regulatory ion release include ion channels and KCl symport. Ion uptake is most frequently mediated by Na+ channels, Na+, K+, 2Cl- cotransport, and Na+/H+ exchange. Chronic adjustment of cell osmolarity is accomplished by the formation or accumulation of organic osmolytes, molecules specifically designed to create intracellular osmolarity without interfering with cellular function. The most widely occurring osmolytes are sorbitol, inositol, glycerophosphorylcholine, betaine, taurine, and amino acids. The osmolytes are either synthesized by or transported into shrunken cells. During cell swelling osmolytes can be rapidly degraded or released. Any given cell may utilize several volume-regulatory mechanisms. Moreover, different mechanisms are utilized in different tissues. The diversity of cell volume regulatory mechanisms allows the cells to defend the constancy of cell volume against a myriad of challenges with relatively little impairment of cellular function.
Behaviour of alatae of<i>Myzus persicae</i>(Sulzer) (Hemiptera: Aphididae) on chemically treated surfaces after tethered flight (1982)

Abstract Alatae of Myzus persicae (Sulz.) were made to fly and then released directly onto untreated or chemically treated surfaces where settling behaviour was studied. Most aphids probed host-leaf surfaces even in the presence of vapour of ( E )-β-farnesene, the main component of aphid alarm pheromone, or when related behaviour-controlling chemicals were painted on the leaf. Flown aphids attempted to probe most surfaces on which they landed, including glass and green paper. However, they did not probe white filter papers. Sublethal deposits of deltamethrin did not prevent initial probing on plant surfaces but caused uncoordinated leg movements which resulted in aphids falling from the plants.
Automatic word stress marking and syllabification for Catalan TTS (2008)

Stress and syllabification are essential attributes for several components in text-to speech (TTS) systems. They are responsible for improving grapheme-to-phoneme conversion rules and for enhancing the synthetic intelligibility, since stress and syllable are key units in prosody prediction. This paper presents three linguistically rule-based automatic algorithms for Catalan text-to-speech conversion: a word stress marker, an orthographic syllabification algorithm and a phonological syllabification algorithm. The systems were implemented and tested. The results gave rise to the following word accuracy rates: 100% for the stress marker algorithm, 99.7% for the orthographic syllabification algorithm and 99.8% for the phonological syllabification algorithm.
<i>Streptococcus mitis</i> Chorioamnionitis after Dental Scaling and Oral Sex (2020)

Bacterial chorioamnionitis should be considered in the differential diagnosis of preterm labour. Oral sex and dental procedures may be risk factors for chorioamnionitis.
Nanoscale assemblies and their biomedical applications (2013)

Nanoscale assemblies are a unique class of materials, which can be synthesized from inorganic, polymeric or biological building blocks. The multitude of applications of this class of materials ranges from solar and electrical to uses in food, cosmetics and medicine. In this review, we initially highlight characteristic features of polymeric nanoscale assemblies as well as those built from biological units (lipids, nucleic acids and proteins). We give special consideration to protein nanoassemblies found in nature such as ferritin protein cages, bacterial microcompartments and vaults found in eukaryotic cells and designed protein nanoassemblies, such as peptide nanofibres and peptide nanotubes. Next, we focus on biomedical applications of these nanoscale assemblies, such as cell targeting, drug delivery, bioimaging and vaccine development. In the vaccine development section, we report in more detail the use of virus-like particles and self-assembling polypeptide nanoparticles as new vaccine delivery platforms.
Identification of envelope glycoprotein encoded by env gene of human T-cell leukemia virus. (1983)

Envelope gene product of human T-cell leukemia virus was identified as a glycoprotein with an apparent molecular weight of 62,000 daltons, by using rabbit antiserum against a synthetic decapeptide whose structure had been predicted from the nucleotide sequence. Sera from patients with adult T-cell leukemia also reacted with this glycoprotein.