gebhart/patrepeval huggingface dataset:
WebMonitor: a Tool for Measuring World-Wide Web Server Performance (1997)

Server performance has become a crucial issue for improving the overall performance of the World-Wide Web. This paper describes WebMonitor, a tool for evaluating and understanding server performance, and presents new results for realistic workloads. WebMonitor measures activity and resource consumption, both within the kernel and in HTTP processes running in user space. WebMonitor is implemented using an efficient combination of sampling and event-driven techniques that exhibit low overhead. Our initial implementation is for the Apache World-Wide Web server running on the Linux operating system. We demonstrate the utility of WebMonitor by measuring and understanding the performance of a Pentium-based PC acting as a dedicated WWW server. Our workloads use file size distributions with a heavy tail. This captures the fact that Web servers must concurrently handle some requests for large audio and video files, and a large number of requests for small documents, containing text or images. Our results show that in a Web server saturated by client requests, up to 90% of the time spent handling HTTP requests is spent in the kernel. These results emphasize the important role of operating system implementation in determining Web server performance. It also suggests the need for new operating system implementations that are designed to perform well when running on Web servers.
Analysis of Mobile Networks Signal Strength for GSM Networks (2016)

GSM Network performance and service quality evaluation are essential steps for mobile operators as the income generated and customer satisfaction is directly linked to network performance and quality. Mobile Network Service Satisfaction assessment, most importantly from the consumer’s perception is necessary to evaluate the network performance and maintain service quality standards. In this project, based on the end user satisfaction stand Point, we consider the service quality offered by mobile telephone operators in Nigeria using the four (4) core GSM networks i.e. MTN, ETISALAT, AIRTEL and GLO as case study. A Drive test report is conducted within Canaan land with the help of the (Network Signal Info Professional) application which would be used to make proposals on how network operators can Improve radio resources as well as provide the requisite QoS (Quality of Service) to subscribers within the Canaan land environs to subscribers within the Canaan land environs. This study would help Network Operators to improve quality, ensure improved network coverage and increase capacity in future. [2]
Nitriding Iron at Lower Temperatures (2003)

The microstructure in the surface layer of a pure iron plate was refined at the nanometer scale by means of a surface mechanical attrition treatment that generates repetitive severe plastic deformation of the surface layer. The subsequent nitriding kinetics of the treated iron with the nanostructured surface layer were greatly enhanced, so that the nitriding temperature could be as low as 300 degrees C, which is much lower than conventional nitriding temperatures (above 500 degrees C). This enhanced processing method demonstrates the technological significance of nanomaterials in improving traditional processing techniques and provides a new approach for selective surface reactions in solids.
Quantitative imaging for discovery and assembly of the metabo‐regulome (2008)

Little is known about regulatory networks that control metabolic flux in plant cells. Detailed understanding of regulation is crucial for synthetic biology. The difficulty of measuring metabolites with cellular and subcellular precision is a major roadblock. New tools have been developed for monitoring extracellular, cytosolic, organellar and vacuolar ion and metabolite concentrations with a time resolution of milliseconds to hours. Genetically encoded sensors allow quantitative measurement of steady-state concentrations of ions, signaling molecules and metabolites and their respective changes over time. Fluorescence resonance energy transfer (FRET) sensors exploit conformational changes in polypeptides as a proxy for analyte concentrations. Subtle effects of analyte binding on the conformation of the recognition element are translated into a FRET change between two fused green fluorescent protein (GFP) variants, enabling simple monitoring of analyte concentrations using fluorimetry or fluorescence microscopy. Fluorimetry provides information averaged over cell populations, while microscopy detects differences between cells or populations of cells. The genetically encoded sensors can be targeted to subcellular compartments or the cell surface. Confocal microscopy ultimately permits observation of gradients or local differences within a compartment. The FRET assays can be adapted to high-throughput analysis to screen mutant populations in order to systematically identify signaling networks that control individual steps in metabolic flux.
Dry oxidation of silicon: A new model of growth including relaxation of stress by viscous flow (1983)

This paper deals with a model of silicon oxidation including stress relaxation by viscous flow during growth. Based on a Deal–Grove process and a Maxwellian stress relaxation approach, an integrodifferential equation giving the inverse growth rate dt/deox vs eox is established. Valid in any case of thickness growth rate dependence, it allows us to fit dry silicon oxidation data on a wide range of oxidation temperature (780–980 °C).
Dataflow Architectures: Flexible Platforms for Neural Network Simulation (1989)

Dataflow architectures are general computation engines optimized for the execution of fine-grain parallel algorithms. Neural networks can be simulated on these systems with certain advantages. In this paper, we review dataflow architectures, examine neural network simulation performance on a new generation dataflow machine, compare that performance to other simulation alternatives, and discuss the benefits and drawbacks of the dataflow approach.
Analysis and Mapping of Plastin Phosphorylation (1998)

Plastins (fimbrins) are a family of three tissue-specific actin-binding proteins. Both L- and T-plastin have been shown to be involved in cytoskeletal reorganization in signal-transduction pathways. Phosphorylation of the leukocyte-specific L-plastin plays important roles in regulating L-plastin function and leukocyte activation. We created L-plastin mutants, changing each of the Ser-5 and Ser-7 residues to alanine. Expression of either mutant in WI38VA13 fibroblasts did not result in phosphorylation. The transfected wildtype L-plastin was phosphorylated in WI38VA13, but its two-dimensional gel pattern suggested that it was phosphorylated on one residue, whereas the endogenous L-plastin in leukocytes was likely phosphorylated on two residues. The nonleukocyte-specific T-plastin, which has an equivalent Ser-7 residue, was not phosphorylated in T-plastin-expressing fibroblasts or in transfected leukocytes. Expression of CK-IIalpha, the catalytic subunit of casein kinase II, resulted in changes of the protein expression profile in leukocytes but not the phosphorylation status of L- or T-plastin. Phorbol myristate acetate induced L-plastin phosphorylation in both leukocytes and fibroblasts, lending support to the view that protein kinase C is the likely candidate kinase for L-plastin phosphorylation.
Phase II Trial of Goserelin and Exemestane Combination Therapy in Premenopausal Women With Locally Advanced or Metastatic Breast Cancer (2015)

A promising option as the treatment of choice for premenopausal patients with locally advanced or metastatic breast cancer (MBC) could be the combination of a luteinizing hormone-releasing hormone analog and an aromatase inhibitor. However, no prospective studies on the efficacy of goserelin with exemestane in locally advanced or MBC premenopausal breast cancer patients have been reported.We present the phase II trial of goserelin plus exemestane in a total of 44 premenopausal women with locally advanced or MBC. All patients received a subcutaneous injection of 3.6 mg goserelin every 4 weeks along with 25 mg exemestane daily. The primary end point was progression-free survival (PFS). The second end point included overall survival (OS), objective response rate (ORR), duration of response (DOR), and clinical benefit rate (CBR) based on complete response (CR), partial response (PR), or stable disease (SD) for ≥6 months.The median PFS was 13 months (range: 2-42 months). The median DOR was 8 months (range: 2-40 months). Two patients achieved CR (4.5%), and 15 patients experienced PR (34.1%). Fifteen patients (34.1%) had SD ≥6 months. The ORR was 38.6%, and the CBR was 65.9%. Primary progressive disease occurred in 15 patients (34.1%). Five patients (11.4%) died during the study period. Because a few patients have died, the median OS has not been reached. Drug therapy was well tolerated. The most frequent grade-3 adverse events were arthralgia (18.2%), skin rash (6.8%), and myalgia (4.5%). No participants withdrew from the study due to drug toxicity.This study suggested that goserelin and exemestane might be highly effective and well-tolerated regimens in premenopausal women with hormone-responsive, locally advanced or MBC.
TiN coating adhesion studies using the scratch test method (1985)

The development of the scratch test method of adhesion assessment is reported. The tangential friction force between the indenter and coating is recorded rather than the acoustic emission which has previously been used to detect the critical load. This method is shown to provide a sensitive and simple means of condition monitoring. Results obtained with this new technique are compared to those obtained by the authors and others using the conventional system, showing that good agreement is achieved. The results of tests on a number of substrate/interface/pretreatment combinations are reported. The implications of the method are discussed especially with regard to the influence of friction on adhesion.
Gas separations in hollow‐fiber adsorbers (1995)

Abstract The adsorption of ethane from helium was measured in beds packed with 2.5 μm zeolite crystals and containing either a single hollow fiber or multiple fibers. THe single‐fiber experiments indicate that the mass‐transfer rate in bends containing zeolite 13X is limited by diffusion across the fiber wall and through macropores. FOr adsorption in single‐fiber beds packed with zeolite 4A, mass transfer is limited by micropore diffusion within the particles. Breakthrough curves from beds containign 13X are adequately described with the linear driving force model, while curves from beds containing 4A are consistent with the Rosen model. Breakthrough curves from beds packed with zeolite 13X and containing multiple fibers can be predicted from the experiments with single‐fiber beds when the fibers are evenly spaced. When fibers are unevenly spaced, the breakthrough curves are more disperse. Unevenly spaced fibers are the normal case. Even when fibers are evenly spaced, the productivity of hollow‐fiber beds is expected to be no greater than that in conventional beds.
Dynamics of a two-mode Bose-Einstein condensate beyond mean-field theory (2001)

We study the dynamics of a two-mode Bose-Einstein condensate in the vicinity of a mean-field dynamical instability. Convergence to mean-field theory (MFT), with increasing total number of particles N, is shown to be logarithmically slow. Using a density-matrix formalism rather than the conventional wave-function methods, we derive an improved set of equations of motion for the mean-field plus the fluctuations, which goes beyond MFT and provides accurate predictions for the leading quantum corrections and the quantum break time. We show that the leading quantum corrections appear as decoherence of the reduced single-particle quantum state; we also compare this phenomenon to the effects of thermal noise. Using the rapid dephasing near an instability, we propose a method for the direct measurement of scattering lengths.
Reductive dissolution of hematite in hydrochloric acid medium by some inorganic and organic reductants : A comparative study (1996)

Dissolution behaviour of naturally occurring hematite ( > 97% Fe 2 O 3 ) in hydrochloric acid medium with or without the presence of reductants has been investigated as a function of acid concentration, temperature, liquid/solid ratio, reductant concentration and particle size. FeCl 2 and SnCl 2 are found as the best reductants among all the organic and inorganic reductants. Addition of FeCl 2 or SnCl 2 to the extent of 2 wt % enhances the formation of Fe 2+ in the solution which in turn increases the percentage of dissolution and also lowers the time of dissolution ( > 90%) from 6 to 3h.
Stokes-Shift-Engineered Indium Phosphide Quantum Dots for Efficient Luminescent Solar Concentrators (2018)

Luminescent solar concentrators (LSCs) show promise because of their potential for low-cost, large-area, and high-efficiency energy harvesting. Stokes shift engineering of luminescent quantum dots (QDs) is a favorable approach to suppress reabsorption losses in LSCs; however, the use of highly toxic heavy metals in QDs constitutes a serious concern for environmental sustainability. Here, we report LSCs based on cadmium-free InP/ZnO core/shell QDs with type-II band alignment that allow for the suppression of reabsorption by Stokes shift engineering. The spectral emission and absorption overlap was controlled by the growth of a ZnO shell on an InP core. At the same time, the ZnO layer also facilitates the photostability of the QDs within the host matrix. We analyzed the optical performance of indium-based LSCs and identified the optical efficiency as 1.45%. The transparency, flexibility, and cadmium-free content of the LSCs hold promise for solar window applications.
Distribution of prostaglandin E2 and prostaglandin F2α receptors in human myometrium (1981)

Human myometrium was studied for specific binding of PGE2 and PGF2 alpha. PGF2 alpha-binding was almost undetectable, but specific binding sites for PGE2 with high affinity (KD = 2.7 +/- 0.4 x 10(-9) M were demonstrated. The binding capacity for PGE2 exhibited a topically different distribution pattern with the highest values in the central parts and low to undetectable levels in the cervical region. Binding characteristics were analyzed by receptor kinetics, revealing a homogeneous receptor population. Binding capacity in uteri obtained from post-menopausal women was of the order of 900-940 fmol/mg protein. Oestrogen pre-treatment and pregnancy were associated with a 3-fold reduction of the PGE2-binding capacity.
The Identification of Zachery-Treated Turquoise (1999)

Over the last 10 years, millions of carats of turquoise have been enhanced by a proprietary process called the Zachery treatment. Tests show that this process effectively improves a stone's ability to take a good polish and may or may not improve a stone's color. It also decreases the material's porosity, limiting its tendency to absorb discoloring agents such as skin oils. Examination of numerous samples known to be treated by this process revealed that Zachery-treated turquoise has gemological properties that are similar to those of untreated natural turquoise, and that the treatment does not involve impregnation with a polymer. Most Zachery-treated turquoise can be identified only through chemical analysis-most efficiently, by EDXRF spectroscopy-as it contains significantly more potassium than its untreated counterpart.
Chemical basis for alteration of an intraocular lens using a femtosecond laser (2017)

The chemical basis for the alteration of the refractive properties of an intraocular lens with a femtosecond laser was investigated. Three different microscope setups have been used for the study: Laser Induced Fluorescence (LIF) microscopy, Raman microscopy and coherent anti-Stokes Raman Scattering (CARS) microscopy. Photo-induced hydrolysis of polymeric material in aqueous media produces two hydrophilic functional groups: acid group and alcohol group. The spectral signatures identify two of the hydrophilic polar molecules as N-phenyl-4-(phenylazo)-benzenamine (C<sub>18</sub>H<sub>15</sub>N<sub>3</sub>) and phenazine-1-carboxylic acid (C<sub>13</sub>H<sub>8</sub>N<sub>2</sub>O<sub>2</sub>). The change in hydrophilicity results in a negative refractive index change in the laser-treated areas.
Direct Solution of the GPS Equations (1996)

A known direct solution of the GPS equation which
yields user position and clock bias is examined and
tested using real GPS data. A comparison of the
position computed using this solution with that
obtained using the popular iterated least squares
solution reveals that the direct solution is in
errors of up to 4 meters. An improved direct
solution is presented which takes in account the
noise associated with the pseudo-range measurements.
The position error obtained when using this solution
is an order of magnitude smaller than that generated
by the direct solution. Finally, an iterated
solution, which is based on the improved direct
solution, is presented. The accuracy of the latter
is comparable to that of the iterated least squares
solution of the GPS equation. The advantage of the
new algorithm over that of the iterated least
squares solution is in its fast convergence rate.
Typically, the new algorithm converges in two
iterations whereas the iterated least squares
solution converges in five, both starting at the
center of earth as the initial position guess. This
advantage of the new algorithms is particularly
important in extraterrestrial missions where the 
initial guess may be far off from the real position.
Five-Gene Model to Predict Survival in Mantle-Cell Lymphoma Using Frozen or Formalin-Fixed, Paraffin-Embedded Tissue (2008)

We here present a validated qRT-PCR-based test for survival prediction in patients with MCL that is applicable to fresh frozen as well as to FFPE tissue specimens. This test may prove useful to guide individualized treatment approaches for patients with MCL.
A human systems biology approach to discover new drug targets in epilepsy (2010)

One of the major challenges in developing novel therapeutics for human epileptic disorders comes from the wide range of brain abnormalities capable of producing epilepsy. In children and adults that undergo epilepsy surgery for treatment of refractory seizures, these abnormalities range from developmental defects to injuries, infections, tumors, and ischemia. Given the many molecular mechanisms likely involved in each of these, finding common therapeutic targets seems a futile task. However, patients undergoing surgery for neocortical seizures have surprisingly similar electrophysiologic abnormalities, which consist of the synchronous firing of large neuronal populations. Surgical removal of these regions is the only means at present time to permanently reduce or eliminate seizures. The precise locations of these hypersynchronous firing regions that produce seizures can be revealed using long-term subdural electrical high-density recordings. This therapeutic strategy not only can dramatically reduce seizures, but also offers the potential to generate molecular and cellular information that can be used to ask why certain regions of the cortex become and remain epileptic. We have taken advantage of these detailed clinical and electrophysiologic human studies by taking a "systems biology" approach to identify novel biomarkers and drug targets in neocortical human epilepsy. In this article, we describe our multidisciplinary systems approach that utilizes a relational database to interrelate clinical, quantitative electrophysiologic, pathologic, and gene expression profiling data together as a means to identify and validate new biomarkers and potential drug targets for human epilepsy.
Distributed On Demand Channel Selection in Multi Channel, Multi Interface Wireless Mesh Networks (2007)

In this paper we present a protocol performing on demand distributed channel selection in multi channel, multi interface wireless mesh networks, based on the exchange of control messages. The link based channel reservation happens almost instantly when data traffic is sent through the network, and does not require long-term traffic profiles or measurements. The protocol is both simulated and implemented using the IEEE 802.11 b/g protocol. We show that in a raster topology, the protocol successfully optimizes the local spectrum usage at 87% of the nodes, and that globally, an equal amount of links is allocated to each of the channels used for the transport of data packets.
Eye movements reveal epistemic curiosity in human observers (2015)

Saccadic (rapid) eye movements are primary means by which humans and non-human primates sample visual information. However, while saccadic decisions are intensively investigated in instrumental contexts where saccades guide subsequent actions, it is largely unknown how they may be influenced by curiosity - the intrinsic desire to learn. While saccades are sensitive to visual novelty and visual surprise, no study has examined their relation to epistemic curiosity - interest in symbolic, semantic information. To investigate this question, we tracked the eye movements of human observers while they read trivia questions and, after a brief delay, were visually given the answer. We show that higher curiosity was associated with earlier anticipatory orienting of gaze toward the answer location without changes in other metrics of saccades or fixations, and that these influences were distinct from those produced by variations in confidence and surprise. Across subjects, the enhancement of anticipatory gaze was correlated with measures of trait curiosity from personality questionnaires. Finally, a machine learning algorithm could predict curiosity in a cross-subject manner, relying primarily on statistical features of the gaze position before the answer onset and independently of covariations in confidence or surprise, suggesting potential practical applications for educational technologies, recommender systems and research in cognitive sciences. With this article, we provide full access to the annotated database allowing readers to reproduce the results. Epistemic curiosity produces specific effects on oculomotor anticipation that can be used to read out curiosity states.
Transgenic Mouse Models of Alzheimer's Disease (2010)

Alzheimer's disease is the most common cause of senile dementia in the United States and Europe. At present, there is no effective treatment. Given the disease's prevalence and poor prognosis, the development of animal models has been a high research priority. Transgenic modeling has been pursued on the basis of the amyloid hypothesis and has taken advantage of mutations in the amyloid precursor protein and the presenilins that cause familial forms of Alzheimer's disease. Modeling has been most aggressively pursued in mice, for which the techniques of genetic modification are well developed. Transgenic mouse models now exist that mimic a range of Alzheimer's disease-related pathologies. Although none of the models fully replicates the human disease, the models have contributed significant insights into the pathophysiology of beta-amyloid toxicity, particularly with respect to the effects of different beta-amyloid species and the possible pathogenic role of beta-amyloid oligomers. They have also been widely used in the preclinical testing of potential therapeutic modalities and have played a pivotal role in the development of immunotherapies for Alzheimer's disease that are currently in clinical trials. These models will, without a doubt, continue to play central roles in preclinical testing and be used as tools for developing insights into the biological basis of Alzheimer's disease.