gebhart/patrepeval huggingface dataset:
ENHANCEMENTS TO THE MODIFIED COMPOSITE PATTERN METHOD OF STRUCTURED LIGHT 3D CAPTURE (2011)

The use of structured light illumination techniques for three-dimensional data acquisition is, in many cases, limited to stationary subjects due to the multiple pattern projections needed for depth analysis. Traditional Composite Pattern (CP) multiplexing utilizes sinusoidal modulation of individual projection patterns to allow numerous patterns to be combined into a single image. However, due to demodulation artifacts, it is often difficult to accurately recover the subject surface contour information. On the other hand, if one were to project an image consisting of many thin, identical stripes onto the surface, one could, by isolating each stripe center, recreate a very accurate representation of surface contour. But in this case, recovery of depth information via triangulation would be quite difficult. The method described herein, Modified Composite Pattern (MCP), is a conjunction of these two concepts. Combining a traditional Composite Pattern multiplexed projection image with a pattern of thin stripes allows for accurate surface representation combined with non-ambiguous identification of projection pattern elements. In this way, it is possible to recover surface depth characteristics using only a single structured light projection. The technique described utilizes a binary structured light projection sequence (consisting of four unique images) modulated according to Composite Pattern methodology. A stripe pattern overlay is then applied to the pattern. Upon projection and imaging of the subject surface, the stripe pattern is isolated, and the composite pattern information demodulated and recovered, allowing for 3D surface representation. In this research, the MCP technique is considered specifically in the context of a Hidden Markov Process Model. Updated processing methodologies explained herein make use of the Viterbi algorithm for the purpose of optimal analysis of MCP encoded images. Additionally, we techniques are introduced which, when implemented, allow fully automated processing of the Modified Composite Pattern image.
Association of CDKN2A/p16INK4A with human head and neck keratinocyte replicative senescence: relationship of dysfunction to immortality and neoplasia. (1996)

We have previously suggested that a gene mapping to chromosome 9p21 could contribute to replicative senescence and suppress cullular immortality in squamous neoplasia. Two candidate genes, the cyclin D1/cyclindependent kinase inhibitors CDKN2A/p16INK4A (p16) and CDKN2B/p15INK4B (p15) have now been identified in this region and we show here that p16 is upregulated when normal human keratinocytes undergo replicative senescence but not when they undergo differentiation. Furthermore, all of 19 immortal neoplastic keratinocyte head and neck lines, including nine showing loss of heterozygosity (LOH) at 9p21, showed undetectable p16 expression, whereas five of six senscent neoplastic cultures showed normal levels of expression. The retinoblastoma protein (pRb) appeared functional in all the cell lines and cultures examined. The mechanism of p16 inactivation appeared to be transcriptional silencing in 10 of 18 lines and homozygous deletions in the rest. Treatment of two of the immortal cell lines which had transcriptionally silent wild type p16 genes with 5aza-2deoxycytidine resulted in the re-expression of p16, thus implicating DNA methylation as one mechanism of transcriptional silencing in the immortal SCC-HN lines. We observed no cases of p16 point mutation. In contrast, the p15 gene was rarely transcriptionally silent and was not deleted in any of the cell lines which showed p16 deletions. Our results show that p16 dysfunction correlates strongly with keratinocyte immortalisation but less strongly with the stage of tumour progression. P16 dysfunction was not related to the neoplastic state or the length of time spent in vitro. The results also suggest that p16 but not p15 is involved in the keratinocyte replicative senescence programme. However, two neoplastic cell cultures which lacked p16 expression were still mortal, suggesting that the loss of p16 is a necessary but insufficient condition for human keratinocyte immortality.
Design and performance of a 250 Hz alexandrite laser (1988)

The design, analysis, and performance of a 250-Hz alexandrite laser are described. Built as the wavelength-selective laser for a molecular laser isotope-separation program, the laser has to satisfy specifications on its tuning band, linewidth, output energy, temporal behavior, and repetition rate required by the process. The key design feature is the use of a tandem rod oscillator with concave curvature on rod ends for thermal lensing compensation. A model was developed to project the stability range and beam quality relative to repetition rate. The performance results of a delivered system are presented and future developments are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Sortilin Expression Is Essential for Pro-Nerve Growth Factor-Induced Apoptosis of Rat Vascular Smooth Muscle Cells (2014)

Our results indicate that sortilin expression characterizes human atheromatous lesions and rat aortic post-injury neointima, and suggest that sortilin represents an important regulator of proNGF-induced SMC apoptosis and arterial remodeling.
Well‐defined drug‐conjugated biodegradable nanoparticles by azide–alkyne click crosslinking in miniemulsion (2011)

Abstract A new type of biodegradable polymer–drug nanoconjugate was fabricated via the combination of oil‐in‐water miniemulsion and Huisgen azide–alkyne click chemistry. Diazide‐functionalized paclitaxel (PTXL) were prepared through functional group transformation on the C‐2′ and C‐7 positions of PTXL and served as both drug carrier and crosslinker. Acetylene‐functionalized polylactide (PLA) was used as the base polymer. Oil‐in‐water miniemulsion technique was used to create nanodroplets with diameters of round 50 nm, which were used as nanoreactors to control the size and morphology of the drug conjugates. Using sodium ascorbate/CuSO 4 ·5H 2 O as catalysts, click reaction was performed within the nanodroplets between the azide functionalities of the PTXL‐based crosslinker and the pendant acetylene groups of the functional PLA. High extent of reaction was confirmed by FTIR analysis and the resulting drug‐conjugated nanoparticles were characterized by dynamic light scattering, transmission electron microscopy, and atomic force microscopy measurements. These NPs exhibited considerable degradation in proteinase K solution within 1 week. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012
Recent developments in the treatment of renal cell carcinoma (2013)

Renal cell carcinoma (RCC) management has been imbued with new interest, in large part due to the recent success of new treatment options for advanced and metastatic disease. This has also been accompanied by less generally well known advances in the understanding of the molecular characterizations of subtypes of RCC with potential to lead to new therapeutic options. Additionally, the urologic oncology community is focusing on nephron-sparing surgical approaches with limited surgery if possible, and in conjunction with interventional radiologists, on ablative procedures for incidentally determined small renal masses. This report reviews some of the new biologic findings of adenocarcinoma of the kidney, and reviews the new therapeutics which continue to change the landscape for treatment of RCC.
Design and Performance of the Cornell ERL DC Photoemission Gun (2009)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation K. Smolenski, I. Bazarov, B. Dunham, H. Li, Y. Li, X. Liu, D. Ouzounov, C. Sinclair; Design and Performance of the Cornell ERL DC Photoemission Gun. AIP Conf. Proc. 4 August 2009; 1149 (1): 1077–1083. https://doi.org/10.1063/1.3215596 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Chemical Synthesis with Inductively Heated Copper Flow Reactors (2010)

Inductively heated copper wire inside a flow microreactor can serve as a source for a catalytic copper species that promotes 1,3-dipolar cycloadditions of alkynes with in situ formed azides to yield 1,2,3-triazoles. The same setup was used to carry out decarboxylations of 2-alkynoic acids and for the intramolecular C-O coupling of 2′-bromobiphenyl-2-carboxylic acid.
Planar-processed tungsten and polysilicon vacuum microelectronic devices with integral cavity sealing (1993)

Solid-state micromachining and planar lithography have been applied in the formation of vacuum microdiode devices. These devices are fabricated with an on-chip vacuum cavity through directional material sealing techniques initiated at vacuum pressure of ∼2×10−6 T. Both tungsten and polycrystalline silicon have been used as cold-cathode emitter materials. The resulting current–voltage characteristics are stable and show good Fowler–Nordheim characteristics to operating currents in excess of 50 μA for wedge-shaped emitter tips. Electrical noise measurements carried out indicate a dominance of flicker noise at low frequencies for both tungsten and polycrystalline silicon microdiodes with the tungsten devices exhibiting excellent characteristics.
Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin‐related modifiers (2011)

Nucleocytoplasmic trafficking of many cellular proteins is regulated by nuclear import/export signals as well as post-translational modifications such as covalent conjugation of ubiquitin and small ubiquitin-related modifiers (SUMOs). Ubiquitination and SUMOylation are rapid and reversible ways to modulate the intracellular localisation and function of substrate proteins. These pathways have been co-opted by some viruses, which depend on the host cell machinery to transport their proteins in and out of the nucleus. In this review, we will summarise our current knowledge on the ubiquitin/SUMO-regulated nuclear/subnuclear trafficking of cellular proteins and describe examples of viral exploitation of these pathways.
A Light-Diffusing Device for Intraoperative Photodynamic Therapy in the Peritoneal or Pleural Cavity (1991)

Light delivery to anatomic areas involved by tumor is critical for effective photodynamic therapy. The authors provide a detailed overview of a light-diffusing device which they have used for intraoperative illumination of the peritoneal and pleural cavities in patients with tumors involving the surfaces of these cavities. Their device represents an inexpensive modification of widely available endotracheal tubes. It has been used to deliver intraoperative photodynamic therapy in over 50 patients without episodes of device failure. When combined with a lipid-based, light-diffusing medium and on-line power/energy density monitoring, it allows homogeneous illumination of these complex surfaces.
The Pursuit Of Symmetry In Wide-Angle Reflective Optical Designs (1980)

The design of wide-angle reflective optical systems has been to a large degree a pursuit of symmetry. Major systems developed in the 1970s can be broken down as modular design combinations of three classical systems--Schmidt, Schwarzschild, and Baker. These configurations are based on the following four constructional principles: 1) aperture stop and correction at the center of curvature of a spherical mirror, 2) confocality of two parabolic mirrors working at infinite conjugates, 3) concentric mirrors, 4) polar strip field coverage. Five notable wide-angle reflective systems developed in '70s are: 1) Two-Axis Baker, 2) Hughes WALRUS, 3) Honeywell Wide-Angle Conical Scanner, 4) Perkin-Elmer Ring Telescope, 5) Corrected Schwarzschild.
Coordinated reset stimulation in a large-scale model of the STN-GPe circuit (2014)

Synchronization of populations of neurons is a hallmark of several brain diseases. Coordinated reset (CR) stimulation is a model-based stimulation technique which specifically counteracts abnormal synchrony by desynchronization. Electrical CR stimulation, e.g. for the treatment of Parkinson’s disease (PD), is administered via depth electrodes. In order to get a deeper understanding of this technique, we extended the top-down approach of previous studies and constructed a large-scale computational model of the respective brain areas. Furthermore, we took into account the spatial anatomical properties of the simulated brain structures and incor- porated a detailed numerical representation of 2·104 simulated neurons. We simulated the subthalamic nucleus (STN) and the globus pallidus externus (GPe). Connections within the STN were governed by spike-timing dependent plasticity (STDP). In this way, we modeled the physiological and pathological activity of the considered brain structures. In particular, we investigated how plasticity could be exploited and how the model could be shifted from strongly synchronized (pathological) activity to strongly desynchronized (healthy) activity of the neuronal populations via CR stimulation of the STN neurons. Furthermore, we investigated the impact of specific stimulation parameters especially the electrode position on the stimulation outcome. Our model provides a step forward towards a biophysically realistic model of the brain areas relevant to the emergence of pathological neuronal activity in PD. Furthermore, our model constitutes a test bench for the optimization of both stimulation parameters and novel electrode geometries for efficient CR stimulation.
Protective Effect of Cyclosporin A on White Matter Changes in the Rat Brain After Chronic Cerebral Hypoperfusion (1995)

Cyclosporin A suppressed both glial activation and white matter changes after chronic cerebral hypoperfusion. These results suggest that immunologic reaction may play a role in the pathogenesis of the white matter changes and that the present model may be useful in investigating the pathophysiology of white matter changes induced by chronic cerebral hypoperfusion.
Graph Theory, Coding Theory and Block Designs (1975)

These are notes deriving from lecture courses given by the authors in 1973 at Westfield College, London. The lectures described the connection between the theory of t-designs on the one hand, and graph theory on the other. A feature of this book is the discussion of then-recent construction of t-designs from codes. Topics from a wide range of finite combinatorics are covered and the book will interest all scholars of combinatorial theory.
Performance Evaluation of Asphalt Binder Modified by Bio-oil Generated from Waste Wood Resources (2013)

Bio-oils are thought to be potentials for petroleum asphalt binders used in asphalt pavement because of the renewability and environmental friendliness. The aim of this study is to investigate the performances of asphalt binders modified by bio-oils generated from waste wood resources. Three types of bio-oils generated from wood waste resources are used in this study: the original bio-oil (OB), de-watered bio-oil (DWB) and polymer modified bio-oil (PMB). OB, DWB and PMB were added into the base asphalt PG 58-28 at 5% and 10% by weight. The rotational viscometer (RV), dynamic shear rheometer (DSR), rolling thin film oven (RTFO), pressure aging vessel (PAV) and bending beam rheometer (BBR) were conducted to evaluate the rheological properties of bio-oil modified asphalt binders. The Superpave™binder specification was used to evaluate the performances of bio-oil modified asphalt binders. The test results show that the addition of bio-oil can lower the mixing temperature of asphalt mixtures while improve the high temperature performance of asphalt binders. However, the medium and low temperature performances were sacrificed. Comparison among the three types of bio-oil modified asphalt binders showed that PMB modified asphalt binders had the highest stiffness, followed by the DWB and OB modified binders. The OB had the lowest effect on the base asphalt binder compared to other two types of bio-oils.
Order-Optimal Data Aggregation in Wireless Sensor Networks Using Cooperative Time-Reversal Communication (2006)

The predominate traffic patterns in a wireless sensor network are many-to-one and one-to-many communication. Hence, the performance of wireless sensor networks is characterized by the rate at which data can be disseminated from or aggregated to a data sink. In this paper, we consider the data aggregation problem. We demonstrate that a data aggregation rate of Theta(logn/n) is optimal and that this rate can be achieved in wireless sensor networks using a generalization of cooperative beamforming called cooperative time-reversal communication.
3D/2D image registration using weighted histogram of gradient directions (2015)

Three dimensional (3D) to two dimensional (2D) image registration is crucial in many medical applications such as image-guided evaluation of musculoskeletal disorders. One of the key problems is to estimate the 3D CT- reconstructed bone model positions (translation and rotation) which maximize the similarity between the digitally reconstructed radiographs (DRRs) and the 2D fluoroscopic images using a registration method. This problem is computational-intensive due to a large search space and the complicated DRR generation process. Also, finding a similarity measure which converges to the global optimum instead of local optima adds to the challenge. To circumvent these issues, most existing registration methods need a manual initialization, which requires user interaction and is prone to human error. In this paper, we introduce a novel feature-based registration method using the weighted histogram of gradient directions of images. This method simplifies the computation by searching the parameter space (rotation and translation) sequentially rather than simultaneously. In our numeric simulation experiments, the proposed registration algorithm was able to achieve sub-millimeter and sub-degree accuracies. Moreover, our method is robust to the initial guess. It can tolerate up to ±90°rotation offset from the global optimal solution, which minimizes the need for human interaction to initialize the algorithm.
A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implications for vaccination. (1992)

Of nine established murine haplotypes, mice of three types (H-2d, H-2u, and H-2q) possess major histocompatibility complex class I glycoproteins able to present an identical viral peptide for recognition and lysis by virus-specific cytotoxic T lymphocytes. Incorporation of this viral epitope into a recombinant vaccinia vaccine and administration of a single dose protects mice with these three haplotypes from an ordinarily lethal challenge of virus. Hence, a common epitope can exist. The sharing of the ability to bind such epitopes among different MHC haplotypes underscores the feasibility of developing an effective cytotoxic T-lymphocyte vaccine for outbred populations like humans.
SOCIAL AND ECONOMIC FACTORS AND ORGANIZATIONAL PERFORMANCE (1982)

Correlations between the error rates of independent government programs involved in similar activities (Aid to Families with Dependent Children and Supplemental Security Income) suggest that both are subject to common environmental influences. Further exploration indicates that as much as 71% of AFDC error rate variance can be explained by area, state size, economic indieatars, and crime rates. The advisability of intervention to reduce error rates taking the economic and social environment into account is urged.
Exposing digital forgeries through chromatic aberration (2006)

Virtually all optical imaging systems introduce a variety of aberrations into an image. Chromatic aberration, for example, results from the failure of an optical system to perfectly focus light of different wavelengths. Lateral chromatic aberration manifests itself, to a first-order approximation, as an expansion/contraction of color channels with respect to one another. When tampering with an image, this aberration is often disturbed and fails to be consistent across the image. We describe a computational technique for automatically estimating lateral chromatic aberration and show its efficacy in detecting digital tampering.
Regulation of mitochondrial metabolism through changes in matrix volume (1994)

Conference Article| May 01 1994 Regulation of mitochondrial metabolism through changes in matrix volume Andrew P. Halestrap Andrew P. Halestrap 1Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 ITD, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1994) 22 (2): 522–529. https://doi.org/10.1042/bst0220522 Article history Received: December 02 1993 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share MailTo Twitter LinkedIn Cite Icon Cite Get Permissions Citation Andrew P. Halestrap; Regulation of mitochondrial metabolism through changes in matrix volume. Biochem Soc Trans 1 May 1994; 22 (2): 522–529. doi: https://doi.org/10.1042/bst0220522 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: CoA, coenzyme A, DCMU, 3-(3,4-dichloropheny1)- 1,l-dimethylurea This content is only available as a PDF. © 1994 Biochemical Society1994 Article PDF first page preview Close Modal You do not currently have access to this content.
Ferric chloride and alum as single and dual coagulants (1983)

A design‐and‐operation diagram for Fe(III) coagulation has been developed by using empirical work and information in the literature about coagulation. This diagram is compared with a previously developed design‐and‐operation diagram for alum coagulation. Empirical work has shown that combining alum and ferric chloride as dual coagulants does not result in a more effective coagulant.
Mars 1834 (1990)

1 er mars. — La proposition de M. Bavoux pour le rétablissement de la loi sur le divorce vient d'être adoptée pour la seconde ou même la troisième fois par la Chambre des députés, à une très grande majorité. Tous les amis de l’ordre espèrent que cette loi immorale sera repoussée de nouveau par la Chambre des Pairs et que son auteur n'osera plus la reproduire dans les sessions suivantes. 2 mars. — Micaud m'a communiqué la seconde Némésis dans laquelle il attaque vertement le système monstrueux...
Generalized linear interpolation of language models (2007)

Despite the prevalent use of model combination techniques to improve speech recognition performance on domains with limited data, little prior research has focused on the choice of the actual interpolationmodel. For merging language models, the most popular approach has been the simple linear interpolation. In this work, we propose a generalization of linear interpolation that computes context-dependent mixture weights from arbitrary features. Results on a lecture transcription task yield up to a 1.0% absolute improvement in recognition word error rate (WER).
[Gemcitabine plus cisplatin versus navelbine plus cisplatin in the treatment of advanced non-small cell lung cancer]. (2003)

The GC combination is as equally active and well tolerated as the VC combination in the treatment of patients with advanced NSCLC.