gebhart/patrepeval huggingface dataset:
The MeetingMachine: interactive workspace support for nomadic users (2003)

Ubiquitous computing embraces both nomadic computing and infrastructure-rich interactive workspaces. Although most effort in these areas to date has focused narrowly on one domain, there are interesting challenges at their intersection. To start a discussion on how some of the benefits of interactive workspaces can be provided to nomadic users, we present MeetingMachine, a digital media projector that incorporates both interactive workspace and nomadic computing technologies in an appliance form factor. As a research effort, the MeetingMachine attempts to bridge the gap between space-embedded and mobile computing models of ubiquitous computing, specifically focusing on the task of sharing information brought into and created during meetings. As a prototype artifact, the design of the MeetingMachine seeks to place ubiquitous computing technology into an appliance, whose role would be similar to that of a digital projector or conference room telephone.
Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response <i>in situ</i> (1996)

The Rel/NF-kappa B proteins, p50, p52, p65, c-Rel, and RelB, constitute a family of transcription factors involved in the positive regulation of a variety of genes during the immune response. Recently, it has been shown that RelB knockout mice have no dendritic cells (DC). An overexpression of p50 has been described in follicular dendritic cells (FDC). A constitutive NF-kappa B activity has been reported in mature macrophages. This led to the hypothesis that some of the Rel/NF-kappa B proteins were key nuclear factors in functions of accessory cells of the immune response. Therefore, we investigated in situ the nuclear localization of Rel/NF-kappa B proteins in accessory cells of the immune system by immunohistochemistry and double labeling by immunofluorescence from five normal human tonsils and five lymph nodes with follicular hyperplasia. Nuclear p65 and c-Rel proteins were found in all cell types including lymphocytes. In germinal centers GC, p50, p52, and RelB were found in the nuclei of FDC only and were not detected in the nuclei of CD68+ cells. In T cell areas, p50, p52, and RelB were found in the nuclei of HLA-DR+ cells with an antigen-presenting cell (APC) morphology. p52 and RelB were detected in the nuclei in both CD1a+ and CD68+ cells from the T cell area, whereas p50 was found only in CD68- and CD1a- cells. Cells with nuclear p50 were negative for the CD38, CD20 and CD2 markers. These results show that, physiologically, high levels of nuclear of p50, p52 and RelB are restricted to accessory cells of the immune system, which include FDC in GC, and DC and macrophages in the T cell zone, that specialized scavenger macrophages from GC do not have detectable levels of p52 and RelB, whereas macrophages from the T cell area, known to present the antigen to T cells, do have both nuclear p52 and RelB, and that in the T cell zone, p52 and RelB are located in nuclei of both CD1a+, CD68+ or both, cells APC, whereas p50 is restricted to CD1a- and CD68- APC. The different patterns of p50, p52 and RelB protein nuclear localization may provide insight into their different roles during the immune response in vivo.
A two-step model for the localization of maternal mRNA in <i>Xenopus</i> oocytes: Involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA (1990)

In an effort to understand how polarity is established in Xenopus oocytes, we have analyzed the process of localization of the maternal mRNA, Vg1. In fully grown oocytes, Vg1 mRNA is tightly localized at the vegetal cortex. Biochemical fractionation shows that the mRNA is preferentially associated with a detergent-insoluble subcellular fraction. The use of cytoskeletal inhibitors suggests that (1) microtubules are involved in the translocation of the message to the vegetal hemisphere and (2) microfilaments are important for the anchoring of the message at the cortex. Furthermore, immunohistochemistry reveals that a cytoplasmic microtubule array exists during translocation. These results suggest a role for the cytoskeleton in localizing information in the oocyte.
Sodium Borohydride as a Reducing Agent in the Sugar Series<sup>1</sup> (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSodium Borohydride as a Reducing Agent in the Sugar Series1M. L. Wolfrom and Kimiko AnnoCite this: J. Am. Chem. Soc. 1952, 74, 22, 5583–5584Publication Date (Print):November 1, 1952Publication History Published online1 May 2002Published inissue 1 November 1952https://pubs.acs.org/doi/10.1021/ja01142a010https://doi.org/10.1021/ja01142a010research-articleACS PublicationsRequest reuse permissionsArticle Views907Altmetric-Citations92LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Optical characterization of tissue for medical diagnostics (1999)

This thesis deals with the development and evaluation of some different optical techniques for tissue characterization. The main aim has been to improve and evaluate such investigative techniques in <i>in vivo</i> studies. In this attempt a key issue has been to gain understanding in the underlying mechanisms of laser-based diagnostics of premalignant and malignant lesions and to evaluate methods for efficient analysis of acquired data. In particular, photon migration-based methods, aiming at the characterization of thick tissues such as the female breast, and laser-induced fluorescence for detection of superficial malignant and premalignant lesions have been studied. Novel time and frequency domain techniques have been employed to determine the optical properties at multiple wavelengths in healthy breast tissue of volunteers. These techniques have proven to be capable of simultaneously determining the fat, water and haemoglobin concentrations in the tissue. This might be essential in the effort to find a reliable intrinsic contrast for optical breast cancer detection. Another technique, based on interference between photon density waves, is improved and its potential for detection of small inhomogeneities in turbid media is evaluated. The potential of laser-induced fluorescence (LIF) spectroscopy to distinguish between malignant, premalignant and benign lesions <i>in vivo</i> in the colon and in the larynx has been studied. This is an interesting technique, since it could provide information about tissue pathology in real-time during endoscopic examination, thus reducing sampling error in the biopsy procedure. LIF could also help the physician characterize and demarcate lesions for optimal therapy. The technique is shown to be a powerful tool during colonoscopy – fluorescence could to a high degree of accuracy distinguish neoplastic polyps from non-neoplastic polyps and normal mucosa. Also the results from the larynx are promising, lesions could be distinguished from normal, and different lesion types could to some degree be separated. Both autofluorescence and the characteristic fluorescence from d-aminolevulinic acid induced protoporphyrin IX have been studied. Different statistical tools for evaluation of fluorescence emission spectra have been used. In particular, multivariate analysis tools such as multivariate linear regression and partial least squares analysis have been employed. Fluorescence imaging of basal cell carcinomas on the skin, using a multi-wavelength and a fluorescence lifetime system has been performed.
An adenovirus recombinant expressing the spike glycoprotein of porcine respiratory coronavirus is immunogenic in swine (1996)

The full-length spike (S) gene of porcine respiratory coronavirus (PRCV) was inserted into the genome of human adenovirus type 5 downstream of the early transcription region 3 promoter. The recombinant virus replicated in cultures of the swine testicle ST cell line and directed the synthesis of S antigen with a maximum yield of approximately 26 micrograms per 10(6) cells. The antigen was cell-associated except in the late phase of the infection, when a small amount (3.5 micrograms per 10(6) cells) was released. The cell-associated antigen consisted of polypeptides of molecular mass 160 kDa and 175 kDa, comigrating with the authentic precursor S' and the mature S protein of PRCV, respectively. The extracellular recombinant antigen corresponded to the 175 kDa mature protein. Some recombinant S protein was exposed on the cell surface and was recognized by neutralization-mediating anti-S monoclonal antibodies. Piglets, inoculated oronasally with the recombinant adenovirus vector developed PRCV-neutralizing serum antibodies and were partially protected against PRCV challenge, demonstrating the potential of live adenovirus as vaccine vector.
Design and realization of multiple quarter-wave phase-shifts UV-written bandpass filters in optical fibers (1997)

Ultraviolet (UV)-written optical fiber bandpass filters based on multiple quarter-wave phase-shifts, up to eight, are presented and modeled. It is demonstrated that the shape of the bandpass peak can be tailored by optimization of the phase-shifts locations. We show that flat top bandpass peak with negligible ripples (<0.01 dB) at the top can be designed and that a tradeoff between nearly rectangular shape and stopband width occurs when gratings containing more than two phase-shifts are to be used. We also present experimental spectral responses of gratings with up to three phase-shifts and comparisons with theoretical results.
Spur reduction techniques in direct digital synthesizers (2002)

Spur reduction techniques used in direct digital synthesizers (DDSs) or numerically controlled oscillators (NCOs) are reviewed. First, the classification and operation of conventional DDSs are reviewed. The pulse output DDS, the sine output DDS, the fractional divider, and the phase interpolation DDS are considered. It is shown that DDSs produce spurs as well as the desired output frequency due to the aliasing of harmonic imperfections in the generated waveform. Next, spur reduction techniques which reduce spurs by destroying the coherence of the aliasing process are discussed. Architectures described are the spurless fractional divider, the Wheatley jitter injection DDS, the randomized DAC (digital-to-analog) DDS, and the nonuniform clock DDS. The spur reduction and phase jitter properties of each architecture are also discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A centralized management framework of network-based Intrusion Detection and Prevention System (2013)

Many network attacks on the internet such as Denial of Service, Port Scanning, and Internet Worm can cause a lot of problems to a network system and tend to be more severe. Therefore, awareness of internet attacks is important. In this paper, we propose a centralized management framework of network-based Intrusion Detection and Prevention System (IDPS) via web application, which allows the network administrator to remotely and efficiently manage the smultiple network-based IDPSsecurity of network system. In our new framework design, multiple network-based IDPSs can be placed in various locations to inspect internet packets in the network. Each IDPS can be easily managed from anywhere and anytime by using a personal computer or a mobile device through a web browser. The web-based management system allows the network administrator to remotely monitor and handle security issues such as managing network port and IP address, updating new network information to identify new malware attacks, as well as displaying the system performance and result analysis. In addition, our network-based IDPS approach can efficiently detect network attacks and internet worms within a short time (i.e., within 2-3 seconds). Several well-known machine learning algorithms can be applied as traffic classification technique in our IDPS approach. From experimental results, we found that our network-based IDPS can analyze internet traffic which include normal packets and malware packets with high accuracy (more than 99%) as well as can immediately protect the network after intrusion detection.
Cavity ringdown laser absorption spectroscopy and time-of-flight mass spectroscopy of jet-cooled copper silicides (1995)

The cavity ringdown technique has been implemented for electronic spectroscopy of jet-cooled CuSi produced in a pulsed UV laser vaporization plasma reactor. A time-of-flight mass spectrometer is used to simultaneously monitor species produced in the supersonic expansion and allows correlation studies to be performed. Seven rotationally resolved vibronic bands have been measured near 400 nm, yielding spectroscopic constants for the 2Σ ground and excited states. Vibronic isotope shifts, together with rotational line positions, permit the unambiguous determination of the spectral carrier and vibronic assignment. Since no ab initio studies for the CuSi molecule exist, a comparison to ab initio studies of the related NiSi molecule is presented. Time-of-flight mass spectrometric measurements indicate the facile formation of CuxSiy clusters containing multiple copper atoms, in contrast to earlier mass spectrometric work on transition metal silicides.
Multistatic SAR image reconstruction based on an elliptical-geometry radon transform (2007)

We propose a geometry and inversion methods for a multistatic, downlooking SAR mode using simple antennas. The resulting generalized Radon transform takes line integrals over ellipses of changing aspect ratio. We apply the method of approximate inverse to the inversion of this transform and show the results of the numerical inversion.
Signature handwriting identification based on generative adversarial networks (2019)

Handwritten signature has been an important identity-verification method since ancient times. Compared with manual handwriting verification, the use of computer image recognition technology for handwriting verification is faster and avoids subjectivity. However, there are still some challenges in traditional image recognition methods, such as feature selection, lack of a standard basis, and low accuracy. For the first time, generative adversarial nets (GAN) technology is adopted to study the task of handwritten signature identification. A special network SIGAN (Signature Identification GAN, SIGAN)is proposed based on the idea of dual learning. The loss value of the trained discriminator of SIGAN is used as the identification threshold. The authenticity of the test handwritten signature is determined by comparing the threshold and loss value of the test image obtained through the network. The experimental data set in this study consists of five hard pen-type signatures, which include some real signatures and some deliberate imitations. The experimental results show that the average accuracy of the SIGAN-based signature identification model is 91.2%, which is 3.6% higher than that of the traditional image classification method.
Therapy to reduce free radicals during early reperfusion does not limit the size of myocardial infarcts caused by 90 minutes of ischemia in dogs. (1988)

It has been postulated that oxygen-centered free radicals are produced in significant quantities upon reperfusion of ischemic myocardium and could cause the death of myocytes that are still reversibly injured at the end of ischemia ("reperfusion injury"). However, we have shown previously that anti-free radical therapies including superoxide dismutase (SOD) and inhibitors of xanthine oxidase did not limit infarct size after 40 minutes of ischemia and 4 days of reperfusion in dogs. To test whether 40 minutes of ischemia is too brief a period to produce the prerequisite conditions for free radical-mediated necrosis upon reperfusion, we studied infarcts produced by 90 minutes of ischemia followed by reperfusion. Dogs in an SOD-catalase group received a 60-minute infusion of SOD (15,000 units/kg) and catalase (55,000 units/kg) beginning 25 minutes before and ending 35 minutes after reperfusion. A second group of dogs received a single injection of the xanthine oxidase inhibitor oxypurinol (20 mg/kg) 25 minutes before reperfusion. Infarct size was assessed histologically relative to the size of the area at risk and to collateral blood flow to the ischemic region. Infarct size as a percentage of the area at risk was similar in the control group (40.7 +/- 5.5%, n = 11), the SOD-catalase group (38.0 +/- 6.4%; n = 8), and the oxypurinol-treated group (41.4 +/- 6.1%; n = 7) [p = not significant (NS) by analysis of variance]. In controls, there was an inverse relation between infarct size and collateral blood flow; neither of the treatments altered this relation (p = NS by analysis of covariance).(ABSTRACT TRUNCATED AT 250 WORDS)
Prevention of Peripheral Venous Catheter Complications With an Intravenous Therapy Team (1998)

An IV therapy team significantly reduced both local and bacteremic complications of peripheral IV catheters. Timely replacement of the catheter appeared to be the most important factor in reducing the occurrence of complications.
CircuitSense (2017)

The rise of Maker communities and open-source electronic prototyping platforms have made electronic circuit projects increasingly popular around the world. Although there are software tools that support the debugging and sharing of circuits, they require users to manually create the virtual circuits in software, which can be time-consuming and error-prone. We present CircuitSense, a system that automatically recognizes the wires and electronic components placed on breadboards. It uses a combination of passive sensing and active probing to detect and generate the corresponding circuit representation in software in real-time. CircuitSense bridges the gap between the physical and virtual representations of circuits. It enables users to interactively construct and experiment with physical circuits while gaining the benefits of using software tools. It also dramatically simplifies the sharing of circuit designs with online communities.
Distress Prediction Models for Rigid Pavements for Texas Pavement Management Information System (1996)

The development of distress prediction models for nonoverlaid portland cement concrete (rigid) pavements in Texas for the Texas Department of Transportation's pavement management information system is described. The regression models presented quantitatively predict distress level versus pavement age and are based on pavement condition data maintained by the Center for Transportation Research at The University of Texas at Austin. Models are available for the following distress types in continuously reinforced concrete pavement (CRCP): punchouts, portland cement concrete patches, asphalt patches, serviceability loss as measured by loss of ride score, transverse crack spacing, and crack spalling. Preliminary models are available for the following distresses in jointed concrete pavement and jointed reinforced concrete pavement: patches, corner breaks, faulted joints and cracks, spalled joints and cracks, transverse crack spacing, and slabs with longitudinal cracks. A sigmoidal regression equation was used for all distress types. Modifying factors to CRCP models, which are intended to capture the effects of structural, environmental, and traffic loading variables, are included. The models for CRCP represent a significant improvement from preliminary estimates made in 1993. The improvements to the models were made possible primarily by data collection efforts undertaken in the summer of 1994.
Simulation of human respiration in fMRI with a mechanical model (2002)

Obtaining functional magnetic resonance images of the brain is a challenging measurement process having a low characteristic signal-to-noise ratio. Images contain various forms of noise, including those induced by physiologic processes. One of the prevalent disturbances is hypothesized to result from susceptibility fluctuations caused by abdominal volume changes during respiration. To test this hypothesis and characterize the contribution of respiration noise to both magnitude and phase images, a mechanical model of a respiring human was constructed. The model was tested by comparing data from the model with that of a resting human. Power spectrum analyses show that the model induces both phase and magnitude disturbances similar to those in the human. The disturbances are directly related to the frequency of the respiration, with the noise most prevalent in the phase images. Though magnitude image noise is hard to identify in the human, the manikin demonstrates the presence of this disturbance. The construction of the manikin rules out motion as the primary source of the observed fluctuations and variation of the electrical properties of the manikin also indicates that signal fluctuations are not primarily due to eddy currents. Therefore, the changes are most probably induced by bulk susceptibility changes correlating with respiration.
Calcineurin-Mediated BAD Dephosphorylation Activates the Caspase-3 Apoptotic Cascade in Traumatic Spinal Cord Injury (2000)

We report here that activation of the caspase-3 apoptotic cascade in spinal cord injury is regulated, in part, by calcineurin-mediated BAD dephosphorylation. BAD, a proapoptotic member of the bcl-2 gene family, is rapidly dephosphorylated after injury, dissociates from 14-3-3 in the cytosol, and translocates to the mitochondria of neurons where it binds to Bcl-x(L). Pretreatment of animals with FK506, a potent inhibitor of calcineurin activity, or MK801, an NMDA glutamate receptor antagonist, blocked BAD dephosphorylation and abolished activation of the caspase-3 apoptotic cascade. These findings extend previous in vitro observations and are the first to implicate the involvement of glutamate-mediated calcineurin activation and BAD dephosphorylation as upstream, premitochondrial signaling events leading to caspase-3 activation in traumatic spinal cord injury.
Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts (2017)

These results indicate that profiling based on the relative activity levels of bacterial community members greatly enhances the capability of detecting interactions between the host and its associated microbes. Finally, the identification of several genes involved in skin cancer suggests that similar to colon carcinogenesis, the resident microbiota may play a role in skin cancer susceptibility and its potential prevention and/or treatment.