gebhart/patrepeval huggingface dataset:
Similarity of the outer capsid protein VP4 of the Gottfried strain of porcine rotavirus to that of asymptomatic human rotavirus strains (1990)

Genomic segment 4 of the porcine Gottfried strain (serotype 4) of porcine rotavirus, which encodes the outer capsid protein VP4, was sequences, and its deduced amino acid sequence was analyzed. Amino acid homology of the porcine rotavirus VP4 to the corresponding protein of asymptomatic or symptomatic human rotaviruses representing serotypes 1 to 4 ranged from 87.1 to 88.1% for asymptomatic strains and from 77.5 to 77.8% for symptomatic strains. Amino acid homology of the Gottfried strain to simian rhesus rotavirus, simian SA11 virus, bovine Nebraska calf diarrhea virus, and porcine OSU strains ranged from 71.5 to 74.3%. Antigenic similarities of VP4 epitopes between the Gottfried strain and human rotaviruses were detected by a plaque reduction neutralization test with hyperimmune antisera produced against the Gottfried strain or a Gottfried (10 genes) x human DS-1 rotavirus (VP7 gene) reassortant which exhibited serotype 2 neutralization specificity. In addition, a panel of six anti-VP4 monoclonal antibodies capable of neutralizing human rotaviruses belonging to serotype 1, 3, or 4 was able to neutralize the Gottfried strain. These observations suggest that the VP4 outer capsid protein of the Gottfried rotavirus is more closely related to human rotaviruses than to animal rotaviruses.
Failure of Common Glycation Assays to Detect Glycation by Fructose (1992)

Serum albumin was modified by in vitro glycation with either fructose or glucose, to see whether the common clinical assays for glycation were able to detect both fructose- and glucose-induced changes in protein structure in diabetes. Although fluorescence measurements showed that fructose causes far more protein damage than glucose, neither serum fructosamine (SFA) nor phenylboronate affinity (PBA) glycation assays reflected these changes. The SFA method implied that fructose causes only about 5% of the glycation induced by glucose; with PBA the proportion was 25%. The thiobarbituric acid- and periodate-based assays also greatly underestimated the true extent of fructation. We discuss these discrepancies with respect to the underlying chemistry, emphasizing the difference between aldehydic and ketonic Amadori products (exemplified by fructose and glucose derivatives, respectively). The implications for detecting fructose-induced secondary diabetic complications are also discussed.
Size of the lens nucleus separated by hydrodissection. (1993)

We measured the extracted central nucleus (diameter and thickness) of 88 eyes (average patient age, 72 years) undergoing extracapsular cataract extraction (ECCE). The average diameter was 6.51 +/- 0.75 mm; the average thickness, 2.96 +/- 0.33 mm. Since the average lens diameter is approximately 10 mm, a corneoscleral incision of 7 to 8 mm in chord length should be sufficient for its removal in most ECCE cases. Accumulation of these data and further analysis correlating them with age and degree and type of cataract in larger series will be useful in determining the smallest possible incision size required for individual patients.
Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome (2010)

The predisposition for scleroderma, defined as fibrosis and hardening of the skin, is poorly understood. We report that stiff skin syndrome (SSS), an autosomal dominant congenital form of scleroderma, is caused by mutations in the sole Arg-Gly-Asp sequence-encoding domain of fibrillin-1 that mediates integrin binding. Ordered polymers of fibrillin-1 (termed microfibrils) initiate elastic fiber assembly and bind to and regulate the activation of the profibrotic cytokine transforming growth factor-beta (TGFbeta). Altered cell-matrix interactions in SSS accompany excessive microfibrillar deposition, impaired elastogenesis, and increased TGFbeta concentration and signaling in the dermis. The observation of similar findings in systemic sclerosis, a more common acquired form of scleroderma, suggests broad pathogenic relevance.
Full-Duplex Relaying for D2D Communication in Millimeter Wave-based 5G Networks (2018)

Device-to-device (D2D) communication, which can offload data from base stations by direct transmission between mobile devices, is a promising technology for fifth generation (5G) wireless networks. However, the limited battery capacity of mobile devices is a barrier to fully exploiting the benefits of D2D communication. Meanwhile, high data rate D2D communication is required to support the increasing traffic demand of emerging applications. In this paper, we study relay-assisted D2D communication in millimeter wave (mmWave)-based 5G networks to address these issues. Multiple D2D user pairs are assisted by full-duplex relays that are equipped with directional antennas. To design an efficient relay selection and power allocation scheme, we formulate a multi-objective combinatorial optimization problem, which balances the trade-off between total transmit power and system throughput. The problem is transformed into a weighted bipartite matching problem. We then propose a centralized relay selection and power allocation algorithm and prove that it can achieve a Pareto optimal solution in polynomial time. We further propose a distributed algorithm based on stable matching. Simulation results show that our proposed algorithms substantially reduce the total transmit power and improve the system throughput compared with two existing algorithms in the literature.
SIMULATION OF A ROTATING DEVICE THAT REDUCES THE AERODYNAMIC DRAG OF AN AUTOMOBILE (2011)

A two-dimensional Computational Fluid Dynamics (CFD) analysis of the Ahmed body is performed using the k-omega-SST turbulence model implemented in the OpenFOAM (OF) software. The analysis is then modified to include a rotating paddle wheel which captures energy from the swirl that forms behind the vehicle. The rotating wheel is implemented using a General Grid Interface (GGI) in the mesh. Flow energy is captured by the wheel and the power generated by the wheel reaches 16.1 W at optimal conditions. Overall drag reductions of up to 7.6% are also found as side-effects of the rotating paddle wheel. Computations are run in parallel on a dual core computer. A mesh of 30,000 cells is used. Y+ values on the walls of the vehicle range from 60 to 500. Tests are run at both fixed and variable paddle wheel angular velocities.
Clinical significance of plasma Antithrombin III in various liver diseases. (2002)

Background : Antithrombin III (AT-III) produced from hepatocytes and endothelial cells is a coagulation inhibitor. The authors investigated the activity levels of AT-III in patients with liver disease and attempt to elucidate the clinical significance of activity levels of AT-III in relation to various liver disease. Methods : This study includes 158 patients with liver disease, who visited the National Police Hospital between October 1997 and March 2002. We performed laboratory tests such as LFT, AFP and either abdominal sonography or abdominal CT. At the same time, AT-III activity levels was measured by chromogenic method using ACL 3000 (IL, Lexington, USA). AT-III activity level of 70-120% was regarded as normal. Results : AT-III activity level of liver cirrhosis patients was decreased along with severity of the disease evaluated by Child-Pugh Classification. AT-III activity level of liver cirrhosis patients and hepatocellular carcinoma patients with liver cirrhosis, whose serum AFP were within normal limits, were 50.112.86% and 75.586.61%, respectively. The difference between the two groups was statistically significant (p
ZnO nanorods for simultaneous light trapping and transparent electrode application in solar cells (2011)

Efficacy of using vertically grown ZnO nanorod array in enhancing electromagnetic field intensity and serving as the top contact layer (transparent electrodes) for solar cells was investigated.
An Overview of Services in Britain for People Who Stutter (1994)

No AccessAmerican Journal of Speech-Language PathologyWorld View1 Jan 1994An Overview of Services in Britain for People Who Stutter Trudy Stewart andPhD Louise Wright Trudy Stewart Department of Speech and Language Therapy, St. James’s University Hospital, Leeds, England LS97TF Google Scholar More articles by this author and Louise Wright Manchester Metropolitan University, Manchester, England Google Scholar More articles by this author https://doi.org/10.1044/1058-0360.0301.05 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationTrack Citations ShareFacebookTwitterLinked In References Association for Stammerers. (1992). Guidelines for health authorities and purchasers of healthcare. London: AFS Publications. Google Scholar College of Speech and Language Therapists. (1991). Standards and guidelines: Communicating quality. London: Author. Google Scholar Hayhow, R., & Levy, C. (1989). Working with stuttering. London: Winslow Press. Google Scholar Rustin, L. (1987). Assessment and therapy programme for dysfluent children. London: NFER Nilsen. Google Scholar Starkweather, C. W. (1987). Fluency and stuttering. London: Prentice-Hall. Google Scholar Williams, R. (1987). Issues in student training in stuttering therapy.In C. Levy (Ed.), Stuttering therapies: Practical approaches. London: Croom Helm. Google Scholar Additional Resources FiguresReferencesRelatedDetails Volume 3Issue 1January 1994Pages: 5-7 Get Permissions Add to your Mendeley library History Published in issue: Jan 1, 1994 Metrics Topicsasha-topicsleader-topicsasha-article-typesCopyright & PermissionsCopyright © 1994 American Speech-Language-Hearing AssociationPDF DownloadLoading ...
A Versatile Synthetic Route to Macromonomers via RAFT Polymerization (2006)

We describe a facile route to prepare functional macromonomers using reversible addition−fragmentation chain transfer (RAFT) polymerization. This was demonstrated in the synthesis of α-functionalized norbornenyl, vinyl, and cinnamyl macromonomers using functional chain transfer agents bearing these end groups. Various homopolymer macromonomers of well-controlled molecular weights were synthesized with near-quantitative incorporation of the end group functionality. The use of norbornenyl and vinyl CTA's resulted in a highly quantitative polymerization of styrene and methyl methacrylate (MMA) monomers yielding well-defined linear macromonomers. On the other hand, monomers with a lower reactivity such as methyl acrylate (MA) exhibited a broader polydispersity. The cinnamyl-functionalized telechelics proved the most challenging due to a competitive chain transfer between the cinnamyl group and the RAFT CTA at higher conversions. To demonstrate utilization of the macromonomer functionality, we synthesized the poly(norbornene-g-PMMA) copolymer based on the ring-opening metathesis polymerization (ROMP) of the norbornenyl-functionalized PMMA macromonomer. The main advantage of this new approach should be in the ability to prepare a variety of macromonomer structures utilizing the mild and tolerant conditions of RAFT polymerization.
Buttonless clicking: Intuitive select and pick-release through gesture analysis (2010)

Clicking is a key feature any interaction input system needs to provide. In the case of 3D input devices, such a feature is often difficult to provide (e.g. vision-based, or tracking systems for free-hand interaction do not natively provide any button). In this work, we show that it is actually possible to build an application that provides two classical interaction tasks (selection, and pick-release), without any button-like feature. Our method is based on trajectory and kinematic gesture analysis. In a preliminary study we exhibit the principle of the method. Then, we detail an algorithm to discriminate selection, pick and release tasks using kinematic criteria. We present a controlled experiment that validates our method with an average success rate equal to 90.1% across all conditions.
BARD1 Participates with BRCA1 in Homology-Directed Repair of Chromosome Breaks (2003)

The BRCA1 tumor suppressor has been implicated in the maintenance of chromosomal stability through homology-directed repair of DNA double-strand breaks. Much of the BRCA1 in cells forms a heterodimeric complex with a structurally related protein BARD1. We report that expression of truncated mouse or human BARD1 peptides capable of interacting with Brca1 results in a homologous-repair deficiency. Repair is mildly reduced in Brca1 wild-type cells and severely reduced in cells that harbor a Brca1 splice product deleted for exon 11. Nuclear localization of the Brca1 or BARD1 peptides is not compromised, implying that the repair deficiency is caused by a more direct effect on repair. The tumor suppressor activity of BRCA1 may require the participation of BARD1 to maintain chromosome integrity through the homologous-repair pathway.
Securing the itinerary of mobile agents through a non-repudiation protocol (2003)

We propose a cryptographic solution to protect the itinerary of mobile agents. We consider real-life applications, where hosts do not act independently but are included in a hierarchical structure. In this structure, at least one trusted authority exists: the certification authority that provides hosts with the necessary cryptographic keys to establish secret and authentic communications between them. In our solution, all agents necessary to the application are launched by a trusted authority (TA). Each agent carries its itinerary as a sequence of encrypted entries. Each entry is readable only by one of the hosts. It includes private information useful only to this host, and the identification of the next host in the agent's itinerary.
Functional unit sharing between stacked processors in 3D integrated systems (2011)

The emerging Through Silicon Via (TSV) based 3D integration technology provides the means to stack two or more dies, enabling a low-latency interface between them. Apart of the immediate advantages of such an approach, e.g., short wires, it also opens research avenues for 3D organizations of computation platforms. In this line of reasoning we propose in this paper to share resources between stacked processors while focusing on Functional Units (FUs) inter-die sharing. The purpose of FU sharing is two fold: (i) it enables inexpensive fault tolerance by allowing, when possible, redundant instruction execution on idle FUs of processors located on other stack dies; and (ii) it can result in performance improvements by remotely executing instructions on idle FUs located on other dies in the 3D stack, when more instructions than locally available FUs are issuable. We evaluated the potential implications of our proposal on a 3D system built with two stacked processors (dies). In this case only a limited error detection capability is enabled and the experimental results indicate that our scheme covers on average 46% of the executed instructions. When performance improvement is targeted an average speedup of 6.9% can be achieved for the applications running on the considered two die stack.
Surface modification of closed plastic bags for adherent cell cultivation (2011)

In modern medicine human mesenchymal stem cells are becoming increasingly important. However, a successful cultivation of this type of cells is only possible under very specific conditions. Of great importance, for instance, are the absence of contaminants such as foreign microbiological organisms, i.e., sterility, and the chemical functionalization of the ground on which the cells are grown. As cultivation of these cells makes high demands, a new procedure for cell cultivation has been developed in which closed plastic bags are used. For adherent cell growth chemical functional groups have to be introduced on the inner surface of the plastic bag. This can be achieved by a new, atmospheric-pressure plasma-based method presented in this paper. The method which was developed jointly by the Fraunhofer IST and the Helmholtz HZI can be implemented in automated equipment as is also shown in this contribution. Plasma process gases used include helium or helium-based gas mixtures (He + N2 + H2) and vapors of suitable film-forming agents or precursors such as APTMS, DACH, and TMOS in helium. The effect of plasma treatment is investigated by FTIR-ATR spectroscopy as well as surface tension determination based on contact angle measurements and XPS. Plasma treatment in nominally pure helium increases the surface tension of the polymer foil due to the presence of oxygen traces in the gas and oxygen diffusing through the gas-permeable foil, respectively, reacting with surface radical centers formed during contact with the discharge. Primary amino groups are obtained on the inner surface by treatment in mixtures with nitrogen and hydrogen albeit their amount is comparably small due to diffusion of oxygen through the gas-permeable bag, interfering with the plasma-amination process. Surface modifications introducing amino groups on the inner surface turned out to be most efficient in the promotion of cell growth.
Agent-based Grid Resource Management (2008)

Abstract. As grid computing becomes a de facto standard for hosting calcul-intensive applications, current grid middleware technologies do not deal with interactive (i.e. non-batch) applications. From a Telco (or any service-provider) perspective, such class of applications is highly sensitive. We propose a grid service platform that dynamically provisions resources for both interactive and batch applications to meet their QoS constraints while ensuring good resource mutualization. Moreover, we believe that relying on an agent-based approach for resource management will allow a more flexible, robust and scalable solution. 1
Commercial CMOS foundry thermal display for dynamic thermal scene simulation (1993)

We report on the performance of a flat-panel thermal display technology, prototype developed at NIST in collaboration with Simon Fraser University and Optical E. T. C., for dynamic thermal scene simulation (DTSS). The pixel elements of the display are composed of thermally-isolated resistive heaters. The main innovation is the fabrication method which uses commercial CMOS integrated circuit (IC) foundries. This method produces a low- manufacturing-cost, high-yield, thermal display technology. Circuits for drive and control are monolithically integrated on the display. The microheating element has a thermal time constant of a few milliseconds and a temperature range of operation from ambient to over 1000 degree(s)C. A 16 X 16 pixel array with a 0.2 mm pixel pitch is presented as a demonstration of the concept; however, the circuit design supports larger sizes (e.g., 256 X $256). This display technology is compatible with DTSS requirements for laboratory and fieldable built-in test/built-in test equipment (BIT/BITE) applications.
Compact and stable SNAP ligand-conjugated quantum dots as a fluorescent probe for single-molecule imaging of dynein motor protein (2015)

Compact SNAP ligand-conjugated quantum dots (<10 nm) with high colloidal stability over a wide range of pH (5-9) have been synthesized as fluorescent probe for the single-molecule imaging of dynein motor protein.
Power Line Maintenance Information System using Low-Power Radio Data Transmission (1994)

Composite Fiber-optic Overhead Ground Wires (OPGWs) have been installed to major power transmission lines. Using these OPGWs, maintenance information systems for power transmission lines have been developed and put into practice. In these systems, however, both sensors and fiber-optic data transmitters are restricted to install on the towers where the OPGW-splicings are made, thus resulting in the restraint of system functions. The authors proposed the application of low-power radio channels and studied the methods both for sensor-signal and OPGW-interpolating data transmission. Specifically, for sensor-signal transmission, it is shown that the method combined with distributed transmission timing and slotted CSMA has superior data transmission performance against hidden terminal problem. Also for OPGW-interpolating data transmission, it is shown that the method using 3 channels of low-power radio has superior performance in view of effective use of radio wave resources. With these results, both sensor-signal and OPGW-interpolating data transmission systems are manufactured and confirmed their practical effectiveness by the field tests.
Resistance to Tungro in Some Wild Relatives of Rice (1991)

This article 'Resistance to Tungro in Some Wild Relatives of Rice' appeared in the International Rice Research Newsletter series, created by the International Rice Research Institute (IRRI). The primary objective of this publication was to expedite communication among scientists concerned with the development of improved technology for rice and for rice based cropping systems. This publication will report what scientists are doing to increase the production of rice in as much as this crop feeds the most densely populated and land scarce nations in the world.
Performance limits of ultra-wideband basic modulation principles (2002)

The performance of an ultra-wideband (UWB) communication system applying pulse position modulation (PPM) is investigated. The optimum impulse shift position in the case of binary overlapping PPM (2OPPM) is analytically derived for the AWGN channel. It is shown that the information throughput of a UWB system in the AWGN channel can be optimized by adjusting the time overlap of the pulse shape used according to the actual signal-to-noise ratio (SNR).
Taxonomic Studies on Some Gram-negative Methylotrophic Bacteria (1987)

One hundred and fifteen cultures, including obligate, restricted facultative and facultative methylotrophs and members of possibly related taxa, were tested for 135 characters based on morphology, physiology and biochemistry and the results were subjected to computer analysis. The polar lipid composition of all the strains was examined. The isoprenoid quinone composition and the mol% G + C value of the DNA were determined for all the obligate and restricted facultative bacteria, and also for some of the other strains representative of the clusters formed in the numerical taxonomic study. The results indicate that the obligate methanol-utilizing bacteria all exhibit a high phenotypic similarity and are taxonomically distinct from the restricted facultative and the facultative methanol-utilizing bacteria examined and from the pseudomonad reference strains. The results also indicate that the obligate methylotrophs and the restricted facultative methylotrophs represent two distinct taxa of generic status: Methylobacillus and a taxon which can be equated with the organisms currently referred to as ‘Methylophilus’.