gebhart/patrepeval huggingface dataset:
Opiniones sobre el desempeño docente y sus repercusiones en la satisfacción profesional y personal de los profesores (2015)

En este trabajo se presenta una revisión sobre el desempeño docente y su relación con la satisfacción/insatisfacción personal y laboral del profesorado que repercute en el profesor y que puede conducir a desgaste en su salud y bienestar. El objetivo de este trabajo se centra en el conocimiento de las opiniones y vivencias del profesorado sobre el desempeño y sus repercusiones en la satisfacción laboral y personal del profesorado e identificar los factores fundamentales de satisfacción/ insatisfacción de los docentes. Los resultados indican que las experiencias positivas del profesorado en el ejercicio de la docencia producen satisfacción y conllevan el desarrollo y la realización personal y profesional, que tienen gran influencia en la enseñanza y el aprendizaje del alumnado, mientras que las experiencias negativas producen insatisfacción personal y profesional.
Three-Hybrid Screens: Inducible Third-Party Systems (2003)

Recent studies have revealed the existence of several molecular complexes either stable, like the RNA polymerase II holoenzyme, transcription factor TFIID, and mediators, or transient as could be observed in the various steps of the transcription process (e.g., initiation, elongation, and termination). These observations point out the fact that regulation of different cellular mechanisms is orchestrated by interactions between molecular species either to modify proteins or to position one of them within a complex that then will be functional. Several techniques such as affinity precipitation, glycerol gradient sedimentation, and the yeast two-hybrid system are currently used to study protein-protein interactions (). These various methods, usually investigating the connection between two partners, account for only the strong (and stable) interactions and neglect the weaker ones. Considering the complexes studied so far, it is suspected and sometimes shown that interactions often occur between more than two proteins (e.g., to stabilize the complex). In an effort to understand the various biologic mechanisms—and in our case gene expression regulation—we were interested in developing the yeast three-hybrid (or trihybrid) system.
ON THE DYNAMICAL DEGRADATION OF DIGITAL PIECEWISE LINEAR CHAOTIC MAPS (2005)

When chaotic systems are realized with finite precisions in digital computers, their dynamical properties are often found to be entirely different from the original versions in the continuous setting. In the literature, there does not seem to be much work on quantitative analysis of such degradation of digitized chaos and how to reduce its negative influence on chaos-based digital systems. Focusing on 1D piecewise linear chaotic maps (PWLCM), this paper reports some findings on a new series of dynamical indicators, which can quantitatively reflect the degradation effects on a digital PWLCM realized with a fixed-point finite precision. On top of that, the paper introduces a new method for studying digital chaos from an algorithmic point of view. In addition, the theoretical results obtained in this paper should be very helpful for the consideration of reducing negative influence of dynamical degradation in real design of various digital chaotic systems. As typical examples, the proposed dynamical indicators are applied to the performance comparison of different remedies for improving dynamical degradation, cryptanalysis of digital chaotic ciphers based on 1D PWLCM, and design of chaotic pseudo-random number generators with desired characteristics.
Identification of Domains in Human β-Hexosaminidase That Determine Substrate Specificity (1996)

The lysosomal beta-hexosaminidases are dimers composed of alpha and beta subunits. beta-Hexosaminidase A (alphabeta) is a heterodimer, whereas hexosaminidase B (betabeta) and S (alphaalpha) are homodimers. Although containing a high degree of amino acid identity, each subunit expresses a unique active site that can be distinguished by a differential ability to hydrolyze charged substrates. The site on the beta-subunit primarily degrades neutral substrates, whereas the alpha-subunit site is, in addition, active against sulfated substrates. Isozyme specificity is also exhibited with glycolipid substrates. Among human isozymes, only beta-hexosaminidase A together with the GM2 activator protein can degrade the natural substrate, GM2 ganglioside, at physiologically significant rates. To identify the domains of the human beta-hexosaminidase subunits that determine substrate specificity, we have generated chimeric subunits containing both alpha- and beta-subunit sequences. The chimeric constructs were expressed in HeLa cells to screen for activity and then selected constructs were produced in the baculovirus expression system to assess their ability to degrade GM2 ganglioside in the presence of GM2 activator protein. Generation of activity against the sulfated substrate required the substitution of two noncontinuous alpha-subunit sequences (amino acids 1-191 and 403-529) into analogous positions of the beta-subunit. Chimeric constructs containing only one of these regions linked to the beta-subunit sequence showed either neutral substrate activity only (amino acids 1-191) or lacked enzyme activity entirely (amino acids 403-529). Neither the chimeras nor the wild-type subunits displayed activator-dependent GM2-hydrolyzing activity when expressed alone. However, one chimeric subunit containing alpha amino acids 1-191 fused with beta amino acids 225 to 556, when co-expressed with the wild-type alpha-subunit, showed activity comparable with that of recombinant beta-hexosaminidase A formed by the co-expression of the alpha- and beta-subunits. This result indicates that the beta-subunit amino acids 225-556 contribute an essential function in the GM2-hydrolyzing activity of beta-hexosaminidase A.
Regulation of the kinin receptors after induction of myocardial infarction: a mini-review (2000)

It is well known that the responses to vasoactive kinin peptides are mediated through the activation of two receptors termed bradykinin receptor B1 (B1R) and B2 (B2R). The physiologically prominent B2R subtype has certainly been the subject of more intensive efforts in structure-function studies and physiological investigations. However, the B1R activated by a class of kinin metabolites has emerged as an important subject of investigation within the study of the kallikrein-kinin system (KKS). Its inducible character under stress and tissue injury is therefore a field of major interest. Although the KKS has been associated with cardiovascular regulation since its discovery at the beginning of the last century, less is known about the B1R and B2R regulation in cardiovascular diseases like hypertension, myocardial infarction (MI) and their complications. This mini-review will summarize our findings on B1R and B2R regulation after induction of MI using a rat model. We will develop the hypothesis that differences in the expression of these receptors may be associated with a dual pathway of the KKS in the complex mechanisms of myocardial remodeling.
The Use of Oxygen Scavengers and Active Packaging to Reduce Oxygen Within Internal Package Environments. (1995)

Abstract : A comprehensive review was performed to characterize the potential for incorporation of oxygen scavengers into package materials to prolong quality retention of food product contents. Sachets or in-package packets or labels containing iron powder or ascorbic acid oxygen scavengers have dominated this technology. Most of the developments and commercializations in the field have been from offshore. Further, until 1994, most of the development in incorporating oxygen scavengers into package materials has been performed offshore. Although the application of sachets has been commercial for more than ten years, incorporation into package materials is not yet commercial. Considerable development is underway in the United States and Japan which could result in commercial package materials containing oxygen scavengers in 1995. jg p.3
An efficient implementation of deep convolutional neural networks on a mobile coprocessor (2014)

In this paper we present a hardware accelerated real-time implementation of deep convolutional neural networks (DCNNs). DCNNs are becoming popular because of advances in the processing capabilities of general purpose processors. However, DCNNs produce hundreds of intermediate results whose constant memory accesses result in inefficient use of general purpose processor hardware. By using an efficient routing strategy, we are able to maximize utilization of available hardware resources but also obtain high performance in real world applications. Our system, consisting of an ARM Cortex-A9 processor and a coprocessor, is capable of a peak performance of 40 G-ops/s while consuming less than 4W of power. The entire platform is in a small form factor which, combined with its high performance at low power consumption makes it feasible to use this hardware in applications like micro-UAVs, surveillance systems and autonomous robots.
Laser metallization for microelectronics and bio-applications (2003)

Excimer lasers were demonstrated to be effective tools in (1) engraving ceramics and polymers, (2) changing irreversibly the surface chemistry of the irradiated material, and (3) restricting these effects to specific areas of interest. In so doing, excimer laser irradiation does open new routes to functionalizing the surface of such diverse and difficult materials, allowing them to be utilized in given applications. In this paper, it is demonstrated how the above three potentialities of excimer laser surface irradiation may be put into practice in producing application-specific metallic tracks onto either sintered ceramics or polymeric materials. To this end, the accent is deliberately put here on the photochemical aspect of this irradiation process. The latter is responsible for modifying the surface stoichiometry and/or structure of irradiated ceramics and silicone rubbers and also, of some of the solid additives which combine to polymers to form so-called thermoplastics. An important consequence of this changing surface chemistry resides in the possibility for decorating the processed surfaces with metal via an electro less technique, thus establishing the ground for a novel metallization process that is presented and examplified.
Self-dsDNA in the pathogenesis of systemic lupus erythematosus (2017)

Systemic lupus erythematosus (SLE) is a systemic and poly-aetiological autoimmune disease characterized by the production of antibodies to autologous double-stranded DNA (dsDNA) which serve as diagnostic and prognostic markers. The defective clearance of apoptotic material, together with neutrophil extracellular traps (NETs), provides abundant chromatin or self-dsDNA to trigger the production of anti-dsDNA antibodies, although the mechanisms remain to be elucidated. In SLE patients, the immune complex (IC) of dsDNA and its autoantibodies trigger the robust type I interferon (IFN-I) production through intracellular DNA sensors, which drives the adaptive immune system to break down self-tolerance. In this review, we will discuss the potential resources of self-dsDNA, the mechanisms of self-dsDNA-mediated inflammation through various DNA sensors and its functions in SLE pathogenesis.
Assembly of 3-Acyloxindoles via CuI/<scp>l</scp>-Proline-Catalyzed Intramolecular Arylation of β-Keto Amides (2006)

[Structure: see text] Intramolecular coupling of beta-keto 2-iodoanilides catalyzed by CuI/L-proline in DMSO occurs at room temperature, affording substituted 3-acyloxindoles in good yield. Electronic effects on the aromatic ring have little influence on this reaction. Variations at the 1, 3, 4, 5, and 6 positions of the oxindoles were achieved by employing the corresponding amides.
An extensible, self contained, layered approach to context acquisition (2011)

Smart phones show increasing capabilities for context-aware applications. The development of such applications involves implementation of mechanisms for context acquisition and context adaptation. To facilitate efficient use of the device's resources and avoid monitoring the same context changes from multiple points, it is necessary that applications share the context acquisition mechanism. In this paper, we intend to develop a generic context acquisition engine which is capable of context capturing, composition and broadcasting. By deploying the engine on a mobile device, context changes are monitored from single point and disseminated to various context aware applications running on the same device. As a proof of concept, the context acquisition engine has been implemented on the Android platform.
Verifiable implementations of geometric algorithms using finite precision arithmetic (1989)

Two methods are proposed for correct and verifiable geometric reasoning using finite precision arithmetic. The first method, data normalization, transforms the geometric structure into a configura- tion for which all finite precision calculations yield correct answers. The second method, called the hidden variable method, constructs configurations that belong to objects in an infinite precision domain-without actually representing these infinite precision objects. Data normalization is applied to the problem of modeling polygonal regions in the plane, and the hidden variable method is used to calculate arrangements of lines.
Differential Growth of Corn (<i>Zea mays</i> L.) Hybrids Seeded at Cold Root Zone Temperatures<sup>1</sup> (1972)

Field observations, which indicated differential growth among corn ( Zea mays L.) hybrids after early seeding but not after later seeding, led to a study of the growth of four hybrids in three different root zone temperature regimes. Initial root zone temperatures of 12, 16, and 20 C, respectively, were subsequently raised by 2, 1, and 0 C with each 2 weeks of growth following the initial 3 weeks after seeding. Hybrid ‘Cornell M‐3’ was most sensitive to cold root zone temperatures; the hybrids ‘Michigan 250,’ ‘Cornell M‐4,’ and ‘Pennsylvania 290’ followed in decreasing order of sensitivity. Percent survival and leaf number were similar for all hybrids, but dry matter accumulation differed among hybrids at the lower temperature regimes. Compared to the other hybrids, Cornell M‐3 accumulated less dry weight of roots, blades, sheaths, and stems and less blade area and stem height after 11 weeks of growth in the 12‐C root temperature regime. Differential growth among hybrids was less apparent when grown at 20 C.
Molecular Distillation of Thermally Supersensitive Liquids. (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular Distillation of Thermally Supersensitive Liquids.W. A. Frank and H. D. KutscheCite this: Anal. Chem. 1964, 36, 11, 2167–2170Publication Date (Print):October 1, 1964Publication History Published online1 May 2002Published inissue 1 October 1964https://doi.org/10.1021/ac60217a039Request reuse permissionsArticle Views98Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts
Neural network differentiation of optic neuritis and anterior ischaemic optic neuropathy. (1996)

Neural network analysis is a useful technique for classification of optic neuropathies, particularly where there is overlap of clinical findings.
Alcadein Cleavages by Amyloid β-Precursor Protein (APP) α- and γ-Secretases Generate Small Peptides, p3-Alcs, Indicating Alzheimer Disease-related γ-Secretase Dysfunction (2009)

Alcadeins (Alcs) constitute a family of neuronal type I membrane proteins, designated Alc(alpha), Alc(beta), and Alc(gamma). The Alcs express in neurons dominantly and largely colocalize with the Alzheimer amyloid precursor protein (APP) in the brain. Alcs and APP show an identical function as a cargo receptor of kinesin-1. Moreover, proteolytic processing of Alc proteins appears highly similar to that of APP. We found that APP alpha-secretases ADAM 10 and ADAM 17 primarily cleave Alc proteins and trigger the subsequent secondary intramembranous cleavage of Alc C-terminal fragments by a presenilin-dependent gamma-secretase complex, thereby generating "APP p3-like" and non-aggregative Alc peptides (p3-Alcs). We determined the complete amino acid sequence of p3-Alc(alpha), p3-Alc(beta), and p3-Alc(gamma), whose major species comprise 35, 37, and 31 amino acids, respectively, in human cerebrospinal fluid. We demonstrate here that variant p3-Alc C termini are modulated by FAD-linked presenilin 1 mutations increasing minor beta-amyloid species Abeta42, and these mutations alter the level of minor p3-Alc species. However, the magnitudes of C-terminal alteration of p3-Alc(alpha), p3-Alc(beta), and p3-Alc(gamma) were not equivalent, suggesting that one type of gamma-secretase dysfunction does not appear in the phenotype equivalently in the cleavage of type I membrane proteins. Because these C-terminal alterations are detectable in human cerebrospinal fluid, the use of a substrate panel, including Alcs and APP, may be effective to detect gamma-secretase dysfunction in the prepathogenic state of Alzheimer disease subjects.
Preparation and Characteristics of Natural Diamond Nuclear Radiation Detectors (1975)

It is shown that natural diamond can be used as a homogeneous conduction counter with near complete charge collection, even over a long period of time. Indeed, polarization effects have been suppressed by making the back contact of the detector injecting under the influence of the applied field in order to compensate for trapped charge carriers. The electric and detection characteristics of these counters have been investigated. Possible application fields are briefly discussed.
Formation of carbon-induced germanium dots (1997)

A very small amount of pre-deposited C on a Si substrate causes island formation after epitaxial growth of less than 2 monolayers Ge. These C-induced Ge dots can be as small as 10 nm in lateral size and 1 nm in height. Their areal density is 1011 cm−2. Intense photoluminescence signal from these small Ge quantum dots is observed reaching a maximum for 2.1±0.3 monolayers of Ge. In the initial stages of island formation, the optical transition of the wetting layer is blue-shifted by strain compensation effects. We propose spatially indirect mechanisms of radiative recombination between electrons confined in the underlying wetting layer and holes confined in the Ge islands.
Proton chemical shifts in NMR spectroscopy. Part 7.1 C–C anisotropy and the methyl effect (1997)

A previous model for the calculation of proton chemical shifts in substituted alkanes based upon partial atomic charges and steric interactions has been modified to include C–C anisotropy contributions and an orientation-dependent methyl γ effect (i.e. Me–C–C–H).The ring inversion in 1,1-dimethylcyclohexane and cis-decalin has been slowed at low temperature and the individual proton chemical shifts assigned, along with those for 5α-androstane.The new scheme (CHARGE4) predicts the proton chemical shifts of a variety of acyclic, cyclic and polycyclic hydrocarbons over 188 data points spanning 2 ppm to within 0.11 ppm, a 40% improvement over the previous model. Systems considered include substituted cyclohexanes and norbornanes, cis- and trans-decalin, perhydrophenalene and anthracene, adamantane and androstane, as well as methylbutanes and tert-butylmethanes.
Urease production as a marker of virulence in<i>Pseudomonas aeruginosa</i> (2014)

(2014). Urease production as a marker of virulence in Pseudomonas aeruginosa. British Journal of Biomedical Science: Vol. 71, No. 4, pp. 175-176.
QoS-Aware Error Recovery in Wireless Body Sensor Networks Using Adaptive Network Coding (2014)

Wireless body sensor networks (WBSNs) for healthcare and medical applications are real-time and life-critical infrastructures, which require a strict guarantee of quality of service (QoS), in terms of latency, error rate and reliability. Considering the criticality of healthcare and medical applications, WBSNs need to fulfill users/applications and the corresponding network's QoS requirements. For instance, for a real-time application to support on-time data delivery, a WBSN needs to guarantee a constrained delay at the network level. A network coding-based error recovery mechanism is an emerging mechanism that can be used in these systems to support QoS at very low energy, memory and hardware cost. However, in dynamic network environments and user requirements, the original non-adaptive version of network coding fails to support some of the network and user QoS requirements. This work explores the QoS requirements of WBSNs in both perspectives of QoS. Based on these requirements, this paper proposes an adaptive network coding-based, QoS-aware error recovery mechanism for WBSNs. It utilizes network-level and user-/application-level information to make it adaptive in both contexts. Thus, it provides improved QoS support adaptively in terms of reliability, energy efficiency and delay. Simulation results show the potential of the proposed mechanism in terms of adaptability, reliability, real-time data delivery and network lifetime compared to its counterparts.
Forecasting and trading high frequency volatility on large indices (2018)

The present paper analyses the forecastability and tradability of volatility on the large S&P500 index and the liquid SPY ETF, VIX index and VXX ETN. Even though there is already a huge array of literature on forecasting high frequency volatility, most publications only evaluate the forecast in terms of statistical errors. In practice, this kind of analysis is only a minor indication of the actual economic significance of the forecast that has been developed. For this reason, in our approach, we also include a test of our forecast through trading an appropriate volatility derivative. As a method we use parametric and artificial intelligence models. We also combine these models in order to achieve a hybrid forecast. We report that the results of all three model types are of similar quality. However, we observe that artificial intelligence models are able to achieve these results with a shorter input time frame and the errors are uniformly lower comparing with the parametric one. Similarly, the chosen models do not appear to differ much while the analysis of trading efficiency is performed. Finally, we notice that Sharpe ratios tend to improve for longer forecast horizons.
IGP Routing Protocol Extensions for Discovery of Traffic Engineering Node Capabilities (2007)

This document specifies an Internet standards track protocol for the Internet community, and requests discussion and suggestions for improvements.