gebhart/patrepeval huggingface dataset:
Automatic synthesis of dynamically configured pipelines supporting variable data initiation intervals (1996)

The authors propose a new approach for synthesizing the dynamically configured pipelines supporting variable data initiation intervals (DIIs). Compared to the previous research where the pipeline synthesis is confined to those with fixed DIIs, the proposed system allows powerful design space exploration by removing the constraints of fixed DIIs. The proposed algorithm tries to optimize the area of pipeline structures by fully utilizing hardware resources to which abstract operations in high-level design descriptions are assigned, while meeting the given timing constraints in the clock cycle time, number of stages, and data initiation sequence. Experimental results on benchmarks show that new design points, efficient in speed and in area, can be found by removing the restriction of fixed DIIs in the synthesis of pipeline structures.
A Study on the Techniques of Expression of Modern Knitwears - Focusing on the Collection's Books of 1990's After - (2000)

The purpose of this study is to discover the techniques and the trends of expression of modern knitwears focusing on the 1990's after. The resorts of this study is as follows: The techniques of expression of knitwears are classified by the sections on the techniques and the styles of expression. The divisions into the techniques are knitting, crochet, macrame, netting, knotting. And the divisions into upon the styles of expressions are color, pattern, texture, relief and seeing through The techniques of expression on the modern knitwears are expressed characteristic of variety and composition, are expended to the art wear by translated into art. According to a wide sense, ecology, ethnic, modern are the themes of knitwears of 1990's after. The characteristic technique of expression according to the themes are expressed by the harmony of image, yarn, color, silhouette, techniques of expression. The modern knitwears are tried by mixed and various techniques, developed to the area of art wear, escaping from simple and practical item.
Rapid and efficient screening for p53 gene mutations by dideoxy fingerprinting. (1995)

Dideoxy fingerprinting (ddF) is an efficient method for detecting single base and other sequence changes in PCR-amplified DNA segments. This screening method is a hybrid between single-strand conformation polymorphism analysis (SSCP) and Sanger dideoxy sequencing. It involves a Sanger sequencing reaction with one dideoxynucleotide followed by non-denaturing gel electrophoresis. We are using ddF to screen for mutations in the p53 tumor suppressor gene in primary breast cancers. ddF detected more than 100 mutations in different regions of the gene, including all types of single-base mutations and microdeletions/microinsertions of various sizes. Furthermore, ddF reliably detected heterozygous mutations, if the region of interest was screened in both directions. In a blinded, prospective study, ddF detected all 25 mutations within exons 4-10 and adjacent flanking intronic regions previously found by direct sequencing. ddF was also useful in scoring two common polymorphisms within the p53 gene. Guidelines for preventing false-positive and false-negative results are summarized.
Ex Vivo Profiling of CD8<sup>+</sup>-T-Cell Responses to Human Cytomegalovirus Reveals Broad and Multispecific Reactivities in Healthy Virus Carriers (2003)

Human cytomegalovirus (HCMV) can establish both nonproductive (latent) and productive (lytic) infections. Many of the proteins expressed during these phases of infection could be expected to be targets of the immune response; however, much of our understanding of the CD8(+)-T-cell response to HCMV is mainly based on the pp65 antigen. Very little is known about T-cell control over other antigens expressed during the different stages of virus infection; this imbalance in our understanding undermines the importance of these antigens in several aspects of HCMV disease pathogenesis. In the present study, an efficient and rapid strategy based on predictive bioinformatics and ex vivo functional T-cell assays was adopted to profile CD8(+)-T-cell responses to a large panel of HCMV antigens expressed during different phases of replication. These studies revealed that CD8(+)-T-cell responses to HCMV often contained multiple antigen-specific reactivities, which were not just constrained to the previously identified pp65 or IE-1 antigens. Unexpectedly, a number of viral proteins including structural, early/late antigens and HCMV-encoded immunomodulators (pp28, pp50, gH, gB, US2, US3, US6, and UL18) were also identified as potential targets for HCMV-specific CD8(+)-T-cell immunity. Based on this extensive analysis, numerous novel HCMV peptide epitopes and their HLA-restricting determinants recognized by these T cells have been defined. These observations contrast with previous findings that viral interference with the antigen-processing pathway during lytic infection would render immediate-early and early/late proteins less immunogenic. This work strongly suggests that successful HCMV-specific immune control in healthy virus carriers is dependent on a strong T-cell response towards a broad repertoire of antigens.
The chronicle of George Boustronios. 1456-1489, translated by R. M. DAWKINS. Melbourne University Press, 1964. In-4°, (University of Melbourne Cyprus expedition, publication n° 2. ) (1966)

Richard Jean. The chronicle of George Boustronios. 1456-1489, translated by R. M. DAWKINS. Melbourne University Press, 1964. In-4°, (University of Melbourne Cyprus expedition, publication n° 2. ). In: Bibliothèque de l'école des chartes. 1966, tome 124, livraison 1. pp. 316-318.
Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions. (2007)

The characterization results showed that incorporation of the model drugs into the microemulsions did not change the microemulsion type. The permeation data exhibited that the nature of the microemulsions was a crucial parameter for transdermal drug delivery. The o/w microemulsions containing hydrophobic drugs provided the highest skin permeation enhancement. In addition, skin permeation was depended on the molecular weight of the model drugs.
Regulating Commercial Drones: Bridging the Gap Between American and European Drone Regulations (2016)

Drones were predicted to be one of the most popular gifts during the 2015 holiday season.'Drones are being manufactured in all shapes and sizes. 2 The cost of drones is decreasing dramatically while the quality of the built-in cameras continues to increase. 3Drones are being used for both recreational and commercial purposes, but the current framework greatly limits commercial drones from being used. 4 In fact, there are no significant technical difference between a recreational drone and a commercial drone.5 Yet still, the Federal Aviation Administration (FAA) has drawn a clear legal distinction between the two. 6 The FAA allows drones to be used for recreational purposes, but only allows drones to be used for commercial purposes after a special permit is acquired. 7 The United States' approach to regulating drones does not distinguish between different size drones, but is instead a "one size fits all" set of regulations. 8 The regulations do, however, differentiate between commercial drones and recreational drones, even though both may pose the same level of risk. 9 The FAA was expected to ease the requirements for commercial drone use, but have not done so."To date, the FAA has not issued any rules to allow commercial use except via its special permit process."'The European Union, on the other hand, has taken a strong pro-business approach."1 The European Aviation Safety .
The flow induced by the torsional oscillations of an elliptic cylinder (1995)

We consider the fluid motion induced when an elliptic cylinder performs small-amplitude torsional oscillations about an axis parallel to a generator which passes through either the centre or a point on the major or minor axis of the ellipse. In common with other fluid flows dominated by oscillatory motion, a time-independent, or steady streaming flow develops. This steady streaming exhibits several unusual and unexpected features, which are confirmed by experiment.
Renal epithelia in long term gradient culture for biomaterial testing and tissue engineering (2005)

In the organism epithelia perform perfect barrier functions. Strong rheological and mechanical influences constitute the normal environment of this tissue throughout life. Most epithelia are exposed to different fluids at the luminal and basal sides. To obtain realistic information about tissue development in modern biomaterial testing and tissue engineering it is necessary to mimick the natural environment of epithelia. Cultured cells are brought in contact with an artificial extracellular matrix to determine whether proper development into a functional epithelium occurs. As under natural conditions the cultures have to withstand mechanical and fluid stress over a prolonged period of time in close contact to a selected biomaterial. However, development of tissue-specific features such as polarization, tightness and transport under in vitro conditions will only occur, if the biomaterial and the culture conditions support tissue development. Leakage, edge damage and pressure differences during culture have to be avoided so that the natural functions of the growing epithelium can develop. Our aim is to generate functional epithelia derived from renal explants containing stem cells, which are microsurgically isolated and placed into specific O-ring carriers for optimal handling. The cells develop in combination with a collagenous matrix from an embryonic into a functional collecting duct (rCD) epithelium. To achieve optimal culture conditions the tissue is placed in a gradient culture container. A typical environment can be simulated by superfusing different culture media at the luminal and basal sides. Within days epithelia growing inside the gradient container build up a physiological barrier, which is maintained during the whole culture period. The described method allows to investigate the influence of new biomaterials over prolonged periods of time.
Does HDR Pre-Processing Improve the Accuracy of 3D Models Obtained by Means of two Conventional SfM-MVS Software Packages? The Case of the Corral del Veleta Rock Glacier (2015)

The accuracy of different workflows using Structure-from-Motion and Multi-View-Stereo techniques (SfM-MVS) is tested. Twelve point clouds of the Corral del Veleta rock glacier, in Spain, were produced with two different software packages (123D Catch and Agisoft Photoscan), using Low Dynamic Range images and High Dynamic Range compositions (HDR) for three different years (2011, 2012 and 2014). The accuracy of the resulting point clouds was assessed using benchmark models acquired every year with a Terrestrial Laser Scanner. Three parameters were used to estimate the accuracy of each point cloud: the RMSE, the Cloud-to-Cloud distance (C2C) and the Multiscale-Model-to-Model comparison (M3C2). The M3C2 mean error ranged from 0.084 m (standard deviation of 0.403 m) to 1.451 m (standard deviation of 1.625 m). Agisoft Photoscan overcome 123D Catch, producing more accurate and denser point clouds in 11 out 12 cases, being this work, the first available comparison between both software packages in the literature. No significant improvement was observed using HDR pre-processing. To our knowledge, this is the first time that the geometrical accuracy of 3D models obtained using LDR and HDR compositions are compared. These findings may be of interest for researchers who wish to estimate geomorphic changes using SfM-MVS approaches.
Macroscopic and Strong Ribbons of Functionality-Rich Metal Oxides from Highly Ordered Assembly of Unilamellar Sheets (2015)

The strong interest in macroscopic graphene and/or carbon nanotube (CNT) fiber has highlighted that anisotropic nanostructured materials are ideal components for fabricating fiber assemblies. Prospectively, employing two-dimensional (2D) crystals or nanosheets of functionality-rich transition metal oxides would notably enrich the general knowledge for desirable fiber constructions and more importantly would greatly broaden the scope of functionalities. However, the fibers obtained up to now have been limited to carbon-related materials, while those made of 2D crystals of metal oxides have not been achieved, probably due to the intrinsically low mechanical stiffness of a molecular sheet of metal oxides, which is only few hundredths of that for graphene. Here, using 2D titania sheets as an illustrating example, we present the first successful fabrication of macroscopic fiber of metal oxides composed of highly aligned stacking sheets with enhanced sheet-to-sheet binding interactions. Regardless of the intrinsically weak Ti-O bond in molecular titania sheets, the optimal fiber manifested mechanical performance comparable to that documented for graphene or CNTs. This work provided important hints for devising optimized architecture in macroscopic assemblies, and the rich functionalities of titania promises fibers with limitless promise for a wealth of innovative applications.
Human Stem Cells Express Substance P Gene and Its Receptor (2000)

We studied the expression of Substance P (SP) and its receptor in an established human stem cell line (TF-1) and primary stem cells derived from human placental cord blood (HPCB). Using reverse transcriptase polymerase chain reaction (RT-PCR) assay, SP mRNA is detected in both TF-1 cells and HPCB stem cells. Among the alpha, beta, gamma, and delta transcripts of the SP gene, only the beta, gamma, and delta transcripts are detectable in these cells. These RT-PCR-amplified transcripts are confirmed by Southern blot assay using a specific SP probe. Sequence analysis of the RT-PCR-amplified products transcribed from mRNA extracted from the HPCB stem cells also confirmed that these transcripts are identical to those found in human neurons. At the protein level, TF-1 cells produced endogenous SP as determined by an enzyme-linked immunosorbent assay (EIA). Capsaicin, a vanillyl fatty acid amide (ingredient of hot pepper), released SP from TF-1 cells. In addition, using RT nested-PCR analysis, we identified the presence of mRNA for neurokinin-1 receptor (NK-1R, the receptor for SP) in both TF-1 cells and HPCB stem cells, which was confirmed by Southern blot and DNA sequencing analysis. The demonstration that human stem cells express SP and its receptor support the notion that SP is biologically involved in the hematopoietic regulating network.
Mixed emotions : unraveling the effects of positive and negative emotions expressed by organizations in crisis on social media (2018)

Social media provide a more natural context to communicate organizational emotions as expressing emotions can increase the perception that the organization speaks with a conversational human voice, leading to more acceptance of the message. However, limited research has been conducted to test how emotional framing can be used in a social mediated channel. In three empirical chapters, the dissertation has been conducted to deepen and expand insights on how positive emotions (e.g., humor, hope) and mixed valence emotions (expressing both positive and negative emotions) can be used in a social mediated context. this dissertation shows that organizations should not only focus on the crisis response strategy but should highlight the importance of emotional framing in communicating the crisis. A crisis should not only be perceived as a negative event but can also be an opportunity for the organization to learn from the crisis and grow. Organizations should also notice the negative and positive aspects of a crisis and select appropriate emotions (positive/negative/mixed) to communicate the crisis, therefore maximize the effectiveness of an organizational response in reputational repair.
Stem cells and proteomics (2006)

The distinctive features of proteomics are large-scale and high throughput. The key techniques of proteomics are two-dimensional gel electrophoresis, mass spectrometry and bioinformatics. Stem cell can differentiate into all kinds of cells, tissues and organs. There are many proteins and cytokines involved in the process of differentiation. Applying proteomics techniques to the research of the complex process of stem cell differentiation is of great importance to study the mechanism and applications of stem cell differentiation.
Persons with partial hand amputations (2002)

This paper sets out to examine the design constraints and issues involved in the development of externally powered hand prostheses in general and externally powered prosthesis for persons with partial hand amputations in particular. A prototype design that resulted from these considerations is described. Currently, there are no commercially available externally-powered partial-hand prostheses. Although a wide range of devices exists for this level of amputation, there are no partial hand prostheses that provide prehension and yet are cosmetic. In addition, the majority of mechanical hands that are available for persons with trans-radial and trans-humeral amputations are not suitable for persons with wrist disarticulations or partial-hand amputations because the resulting prostheses are too long. The authors believe that preservation of the wrist motion for positioning of the terminal device is of paramount importance to achieving maximum function and cosmesis. In a partial hand prosthesis the only space for any mechanisms is in the digits. The challenge is to be able to fit all the requisite mechanisms and electronics in this highly confined volume and still have reasonable performance. The availability of small motors (MicroMo MM1016) operating in synergy (Childress, 1973) makes such a device possible.
Nonencephalitogenic CD4-CD8- V alpha 2V beta 8.2+ anti-myelin basic protein rat T lymphocytes inhibit disease induction (1991)

Recently there has been a number of reports suggesting that CD4-CD8- T cells participate in the processes of inflammatory reaction. In an attempt to delineate the distinctive functions of double negative (DN) T lymphocytes in an autoimmune-induced disease, we isolated and cloned such T cells, along with control CD4+ cells, from Lewis rats immunized with guinea-pig myelin basic protein in CFA. Both clones proliferated in response to the guinea-pig myelin basic protein and its synthetic encephalitogenic peptide, and expressed the same TCR V genes homologous to the mouse V alpha 2 and V beta 8.2 families that appear to be the defining entity of experimental autoimmune encephalomyeltis (EAE). Moreover, the TCR D and J region gene products of the DN cell were found to be similar to another encephalitogenic rat T cell clone. The two T clones did not differ markedly in their ability to produce TNF and IL-2 and to adhere to vascular wall-derived extracellular matrix- and laminin-coated plates. Surprising, therefore, was the finding that, although the CD4+ T lymphocytes were capable of inducing EAE, the DN cells did not elicit disease but rather inhibited subsequent EAE induction. Thus, TCR V alpha 2V beta 8.2 and its junctional region gene products are not the only prerequisite segment for a T cell to become encephalitogenic. We suggest that the important determinants of the T cell ability to induce disease are features of the T cell, other than or in addition to, the T cell receptor.
Boundary conditions for light propagation in diffusive media with nonscattering regions (2000)

The diffusion approximation proves to be valid for light propagation in highly scattering media, but it breaks down in the presence of nonscattering regions. We present a compact expression of the boundary conditions for diffusive media with nonscattering regions, taking into account small-index mismatch. Results from an integral method based on the extinction theorem boundary condition are contrasted with both Monte Carlo and finite-element-method simulations, and a study of its limit of validity is presented. These procedures are illustrated by considering the case of the cerebro-spinal fluid in the brain, for which we demonstrate that for practical situations in light diffusion, these boundary conditions yield accurate results.
Cleavage of X−H Bonds (X = N, O, or C) by Copper(I) Alkyl Complexes To Form Monomeric Two-Coordinate Copper(I) Systems (2005)

The monomeric copper(I) alkyl complexes (IPr)Cu(R) [R = Me or Et; IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene] react with substrates that possess N-H, O-H, and acidic C-H bonds to form monomeric systems of the type (IPr)Cu(X) (X = anilido, phenoxide, ethoxide, phenylacetylide, or N-pyrrolyl) and methane or ethane. Solid-state X-ray crystal structures of the anilido, ethoxide, and phenoxide complexes confirm that they are monomeric systems. Experimental studies on the reaction of (IPr)Cu(Me) and aniline to produce (IPr)Cu(NHPh) suggest that a likely reaction pathway is coordination of aniline to Cu(I) followed by proton transfer to produce methane and the copper(I) anilido complex.
Frequency reuse and system deployment in local multipoint distribution service (1999)

Following the FCC's auctions for local multipoint distribution service spectrum, the US spectrum holders are expected to go on a rapid move, first toward evaluating the technology in trials, and further toward gradual deployment and commercial availability. The LMDS spectrum will offer new ways to break the local loop bottleneck by delivering a full suite of high-speed service interfaces to business and residential customers. The problem for developers and operators consists in how to efficiently exploit the wide amount of available spectrum for LMDS against challenges such as the propagation characteristics, and the availability and cost of radio technology at millimeter waves. This article presents some of the alternatives and options related to the efficient deployment of LMDS. It starts with a presentation of the duplexing techniques and their specific trade-off and applicability in LMDS. Further on, we consider the subject of frequency planning and reuse. This consists of an overview of the basic mechanisms and algorithms involved, links to related topics in mobile cellular systems, and architectures for reuse optimization in LMDS. Of special interest is the issue of LMDS deployment for gradual capacity upswing, starting with low investment in equipment and a low number of cells and sectors, and going toward more cells with higher capacity per cell. To serve this problem a novel approach to the use of alternative polarization in gradually increasing capacity and sectorization is presented. To justify the target of high capacity and bandwidth utilization, an example of capacity estimation is also given.
Construction and Analysis of the NCI-EDRN Breast Cancer Reference Set for Circulating Markers of Disease (2014)

Availability of prospectively collected samples should improve future validation efforts.