gebhart/patrepeval huggingface dataset:
Coenzyme Q<sub>10</sub> levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects (1997)

The activities of complex I and complex II/III in platelet mitochondria are reduced in patients with early, untreated Parkinson's disease. Coenzyme Q10 is the electron acceptor for complex I and complex II. We found that the level of coenzyme Q10 was significantly lower in mitochondria from parkinsonian patients than in mitochondria from age- and sex-matched control subjects and that the levels of coenzyme Q10 and the activities of complex I and complex II/III were significantly correlated.
Performance assessment of a pushrim-activated power-assisted wheelchair control system (2002)

Wheelchairs are an important form of mobility for people with disabilities. For many years, there have only been three wheelchair varieties: electric-powered wheelchairs, scooters and manual wheelchairs. Recently, wheelchairs have been developed that use a combination of human power and electric power. The human power is delivered by the arms through the pushrims while the electric power is delivered by a battery through two electric motors. The shared control system for a pushrim-activated power-assisted wheelchair (PAPAW) must account for the human behavior and the interaction with the device. The PAPAW uses a form of gain scheduling based upon events recorded from the pushrim torque. The control system significantly altered (p<0.05) selected variables from pushrim torque curves for manual wheelchair propulsion and PAPAW operation as desired. The peak torque was reduced by over 50%, and the time on the rim was nearly doubled with the PAPAW. The PAPAW provided intuitive control and was capable of significantly reducing the strain on the upper extremities commonly associated with secondary disabling conditions among manual wheelchair users.
The Benefits of Dense Stereo for Pedestrian Detection (2011)

This paper presents a novel pedestrian detection system for intelligent vehicles. We propose the use of dense stereo for both the generation of regions of interest and pedestrian classification. Dense stereo allows the dynamic estimation of camera parameters and the road profile, which, in turn, provides strong scene constraints on possible pedestrian locations. For classification, we extract spatial features (gradient orientation histograms) directly from dense depth and intensity images. Both modalities are represented in terms of individual feature spaces, in which discriminative classifiers (linear support vector machines) are learned. We refrain from the construction of a joint feature space but instead employ a fusion of depth and intensity on the classifier level. Our experiments involve challenging image data captured in complex urban environments (i.e., undulating roads and speed bumps). Our results show a performance improvement by up to a factor of 7.5 at the classification level and up to a factor of 5 at the tracking level (reduction in false alarms at constant detection rates) over a system with static scene constraints and intensity-only classification.
Dynamic threshold adjustment in a proximity-based location tracking system using reference modules (2015)

In recent years, location tracking systems have become important in areas such as transportation, shopping, logistics and medicine. One of the most recent approaches are proximity-based location tracking systems, which use the received signal strength (RSSI) measured between a sender and an anchor module. The advantages of these systems are high scalability, minimal calibration effort and low costs. However, there are also disadvantages e.g. the fluctuating signal strength under certain circumstances in the environment. To detect, if an object has entered a predefined region, the RSSI must exceed a specified threshold. When the current signal fluctuates due to obstacles (other objects, people, etc.) the static threshold does not apply for the defined region any longer. In this case automatic adjustments of the threshold are made with the help of a reference module. Various factors are measured between reference, anchor as well as a sender module and subsequently used to correct the static threshold. The dynamic adjustment was tested through three experiments and showed satisfactory results concerning the hypotheses. For further research, additional factors might need to be included to make the proposed method more dynamic and responsive to the environment.
Relationship analysis between user's contexts and real input words through Twitter (2010)

In this paper, we propose a method to evaluate effectiveness of our proposed context-aware text entry by using Twitter. We focus on ”geo-tagged” public tweets because they include user's important contexts, real location and time. We also focus on TV program listing because 50% traffic of iPhone in Japan is generated from our home, in which I often tweets in watching a TV. Cyclical collecting system based on Streaming API and Search API of Twitter is proposed for gathering the target tweets efficiently. In order to find the relationship between user's contexts and really used words, we compare really-tweeted words with words obtained from Local Search API of Yahoo! Japan that is used for our context-aware text entry and words obtained from TV program listing. We analyze 471274 tweets that have been collected from 15 December 2009 to 10 June 2010 for specifying the relationship to landmark information and TV program. As a result, we show that 5.1% of tweets include landmark words, and 9% of tweets include TV program words. Additionally, we bring out that there are location dependent words and time dependent words.
Ruthenium-Catalyzed Transformations of Amino Alcohols to Lactams (1991)

1,4- and 1,5-Amino alcohols undergo oxidative condensation upon treatment with dihydridotetrakis(triphenylphosphine)ruthenium(II) catalyst in the presence of a hydrogen acceptor to give the corresponding lactams. The principle of the present reaction can be extended to amide formation from aromatic aldehydes and secondary amines.
A Short Synthesis of a Novel Ring-Expanded Purine and Its Nucleoside Analogue Containing the Imidazo[4,5-<i>e</i>][1,3]diazepine Ring Skeleton with Multiple Amino Substituents Attached to the 7-Membered Ring (1994)

Abstract The synthesis of 4,6,8-triaminoimidazo[4,5-e][1,3]diazepine (1) and its nacleoside analogue (6) are reported. The heterocycle was prepared in a single step by condensation of 4,5-dicyanoimidazole with guanidine. The 5,7-fused ring structure of 1 was distinguished from the other possible 5:5-fused isomer 2 by preparing the 15N-labeled heterocycle (1∗) and exploring its 15N-1H coupling patterns in both 1H and 15N NMR spectra. These spectral patterns also enabled establishment of the triamino tautomeric form of 1 as assigned. Compound 1, a novel ring-expanded (“fat”) analogue of purine, is anticipated to be planar and aromatic as predicted by molecular modeling. The 1 -benzyl analogue (4), a protocol for the ribosyl analogue 6, was similarly prepared from 1-benzyl-4,5-dicyanoimidazole. The nucleoside 6 was prepared by the modified Vorbrülggen ribosylation of 1. The position of ribosylation was unequivocally established by an unambiguous synthesis of 6 from condensation of 1 -(2′,3′,5-tri-O-benzoyl-β-D-ribofuranosyl)-4,5-dicyanoimidazole (7) with guanidine in a solution of sodium methoxide in methanol. The nucleoside 7 was prepared by the Vorbrüggen ribosylation of 4,5-dicyanoimidazole.
Real-Time Pose-Invariant Face Recognition by Triplet Pose Sparse Matrix from Only a Single Image (2014)

In this paper, a novel method for real-time pose-invariant face recognition is proposed from only a single image in a gallery including any facial expressions. A 3D Facial Expression Generic Elastic Model (3D FE-GEM) is proposed to reconstruct 3D model of each human face in the present database using only a single 2D frontal image. Then, for each person in the database, a Triplet Pose Sparse Matrix (TPSM) is created from all face poses by rotating the 3D reconstructed models and extracting features in rotated face. Each TPSM is subsequently rendered based on triplet angles of face poses. Before matching to TPSM, an initial estimate of triplet angles of face poses is obtained in the test face image/video using an automatic head pose estimation approach. Then, an array of the TPSM is selected based on the estimated triplet angles for each subject. Finally, the selected arrays from TPSMs are compared with target image by joint dynamic sparse representation classification. Favorable outcomes were acquired to handle pose and expression changes on the available image and video databases based on the proposed method compared to several state-of-the-arts in pose-invariant face recognition.
New Cyanate Ester and Poly(<i>p</i>-phenylene) Resins with Low-Moisture Absorption and Improved Thermal Stability (2009)

New cyanate ester and poly-p-phenylene (P3) resin materials that exhibit significantly reduced moisture absorption while maintaining thermal stability have been developed and their key properties investigated. The replacement of a single carbon atom by a silicon atom in the repeat unit chemical structure of the di(cyanate ester) of Bisphenol A (BADCy) resulted in a new silicon-containing resin (SiMCy) with a 50% reduction in water uptake and higher char yields in air after curing. Thermosetting Navy P3 resins were found to exhibit moisture uptake similar to poly-p-phenylene thermoplastics, a level which is about 85% lower than thermosetting polyimides. Like their thermoplastic counterparts, the Navy P3 resins exhibit outstanding resistance to high temperature degradation. Unlike their thermoplastic counterparts, these resins form low viscosity melts that are easily formed into carbon fiber reinforced composites.
A micromachined continuous ink jet print head for high-resolution printing (1998)

The aim of this work was the development of an ink jet imaging unit for offset printing formes. A high-resolution (1200 dpi) ink jet print head based on the principle of continuous ink jet printing is presented. Using the outstanding properties of silicon bulk micromachining this microsystem was fabricated. It consists of a multinozzle print head, a charging electrode array and an array of ink shields to drain off the unused ink.
Encyclopedia of Polymer Applications (2021)

Undoubtedly the applications of polymers are rapidly evolving. Technology is continually changing and quickly advancing as polymers are needed to solve a variety of day-to-day challenges leading to improvements in quality of life. The Encyclopedia of Polymer Applications presents state-of-the-art research and development on the applications of polymers. This groundbreaking work provides important overviews to help stimulate further advancements in all areas of polymers. This comprehensive multi-volume reference includes articles contributed from a diverse and global team of renowned researchers. It offers a broad-based perspective on a multitude of topics in a variety of applications, as well as detailed research information, figures, tables, illustrations, and references. The encyclopedia provides introductions, classifications, properties, selection, types, technologies, shelf-life, recycling, testing and applications for each of the entries where applicable. It features critical content for both novices and experts including, engineers, scientists (polymer scientists, materials scientists, biomedical engineers, macromolecular chemists), researchers, and students, as well as interested readers in academia, industry, and research institutions.
AtNPR4 from <i>Arabidopsis thaliana</i>: expression, purification, crystallization and crystallographic analysis (2018)

Salicylic acid (SA) is an important phytohormone that is involved in the regulation of plant defence, growth and development. A large number of proteins have been shown to have the ability to interact with SA, and NPR4 has been demonstrated to be a receptor of SA that plays significant roles in the innate immune response of plants. In this study, Spodoptera frugiperda (Sf9) cells were used to express full-length AtNPR4 from Arabidopsis thaliana. To facilitate crystallization, T4 lysozyme (T4L) was added to the N-terminus of the AtNPR4 protein. The recombinant T4L-AtNPR4 protein was expressed, purified and crystallized using the sitting-drop and hanging-drop vapour-diffusion methods. The T4L-AtNPR4 crystals have symmetry consistent with space group C2, with unit-cell parameters a = 93.7, b = 85.8, c = 88.2 Å, β = 90° and one molecule per asymmetric unit. The best crystal diffracted to a resolution of 2.75 Å. Structure determination is in progress.
Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats (2009)

Overall, these observations suggest that the predominant effect of auraptene was to delay the development of tumors possibly through the suppression of cyclin D1 expression. These results point to the potential chemopreventive effects of auraptene in mammary carcinogenesis.
Electronic Structure of Monolayer Hexagonal Boron Nitride Physisorbed on Metal Surfaces (1995)

By using angle-resolved electron spectroscopic methods, we have investigated a monolayer film of hexagonal boron nitride ($h$-BN) epitaxially formed on Ni(111), Pd(111), and Pt(111). The electronic structure of the monolayer $h$-BN is almost independent of the substrate, which is in striking contrast with the case of monolayer graphite [A. Nagashima et al., Phys. Rev. B 50, 4756 (1994)]. The comparison of the present data with those for typical physisorbed systems indicates physisorption of the BN film.
Failure to induce organ-specific autoimmunity by breaking of tolerance: importance of the microenvironment (1998)

Peripheral tolerance is considered to be a safeguard against autoimmunity. Using a TCR-transgenic mouse system displaying peripheral tolerance against a liver-specific MHC class I Kb antigen, we investigated whether the breaking of tolerance would result in autoimmunity. Reversal of tolerance was achieved by simultaneous challenge with cells expressing the Kb autoantigen and IL-2. Tolerance could not be broken with IL-2 alone or when Kb- and IL-2-expressing cells were applied to different sites of the mice. However, despite the presence of activated autoreactive T cells that were able to reject Kb-positive grafts no autoaggression against the Kb-positive liver was observed. These results indicate that breaking of tolerance per se is not sufficient to cause liver-specific autoimmunity. However, when in addition to breaking tolerance the mice were infected with a liver-specific pathogen, autoaggression occurred. Thus, in this system at least two independent steps seem to be required for organ-specific autoimmunity: reversal of peripheral tolerance resulting in functional activation of autoreactive T cells and conditioning of the liver microenvironment which enables the activated T cells to cause tissue damage.
Thallium superconductor reaches 125 K (1988)

Two recently reported superconductors containing thallium are discussed. Scientists from the University of Arkansas have prepared thallium-barium-copper-oxygen materials that retain zero resistance up to 106 K. Researchers at the IBM Almaden Research Center have announced preparation of thallium-calcium-barium-copper-oxygen material that achieves zero resistance and displays the Meissner effect at 125 K. The stability and crystal structure of the latter compound are discussed.
Evaluation of Thermal and Film Forming Properties of Acrylic Aqueous Polymer Dispersion Blends: Application to the Formulation of Sustained-Release Film Coated Theophylline Pellets (1995)

Aqueous acrylic polymer dispersions were blended in order to improve processing and film formation from acrylic polymers with poor film forming properties and/or to obtain sustained-release film coated pellets with optimal barrier properties according to the physicochemical and pharmacokinetic requirements of the active substance.Heterogeneous film structures are generally obtained from blends containing an association of hard acrylic polymers (Eudragit* RS30D, S100) with the soft Eudragit* NE30D when the drying temperature is lower than the minimum film forming temperature (MFT) of the hard acrylic polymers. The Tg and MFT values of the hard acrylic polymers are not modified in the presence of the soft polymer as shown by the thermograms of these blends which are generally characterized by two individual glassy transitions.On the other hand, a wide range of drug dissolution profiles can be obtained from film coated pellets either by using, in different proportions, the insoluble but readily permeable Eudragit* RL30D in association with the less permeable Eudragit* RS30D in order to obtain pH-independent permeability membrane, or by mixing the anionic methacrylic acid copolymers (L30D, S100) with the neutral NE30D in order to obtain pH-dependent permeability film coated pellets showing higher dissolution release rates at intestinal pH values.
Efficacy and safety of the long‐acting muscarinic antagonist GSK233705 delivered once daily in patients with COPD (2012)

All doses of GSK233705 demonstrated bronchodilatory activity and were well tolerated. Although the onset of bronchodilation was rapid, it was not sustained over 24 h making it unsuitable for once-daily dosing.
Kinetic evidence of reaction diffusion during the polymerization of multi(meth)acrylate monomers (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetic evidence of reaction diffusion during the polymerization of multi(meth)acrylate monomersK. S. Anseth, C. M. Wang, and C. N. BowmanCite this: Macromolecules 1994, 27, 3, 650–655Publication Date (Print):January 1, 1994Publication History Published online1 May 2002Published inissue 1 January 1994https://pubs.acs.org/doi/10.1021/ma00081a004https://doi.org/10.1021/ma00081a004research-articleACS PublicationsRequest reuse permissionsArticle Views1957Altmetric-Citations286LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress (2005)

Endothelium-derived microparticles have recently been described as a new marker of endothelial cell dysfunction. Increased levels of circulating microparticles have been documented in inflammatory disorders, diabetes mellitus, and many cardiovascular diseases. Perturbations of angiogenesis play an important role in the pathogenesis of these disorders. We demonstrated previously that isolated endothelial microparticles (EMPs) impair endothelial function in vitro, diminishing acetylcholine-induced vasorelaxation and nitric oxide production by rat aortic rings and simultaneously increasing superoxide production. Herein, using the Matrigel assay of angiogenesis in vitro and a topological analysis of the capillary-like network by human umbilical vein endothelial cells (HUVECs), we investigated the effects of EMPs on formation of the vascular network. All parameters of angiogenesis were affected by treatment for 48 h with isolated EMPs in a concentration of 10(5) but not 10(3) or 10(4) EMPs/ml. The effects included decreases in total capillary length (24%), number of meshes (45%), and branching points (36%) and an increase in mesh area (38%). The positional and topological order indicated that EMPs affect angiogenic parameters uniformly over the capillary network. Treatment with the cell-permeable SOD mimetic Mn(III)tetrakis(4-benzoic acid) porphyrin chloride (Mn-TBAP) partially or completely restored all parameters of angiogenesis affected by EMPs. EMPs reduced cell proliferation rate and increased apoptosis rate in time- and dose-dependent manners, and this phenomenon was also prevented by Mn-TBAP treatment. Our data demonstrate that EMPs have considerable impact on angiogenesis in vitro and may be an important contributor to the pathogenesis of diseases that are accompanied by impaired angiogenesis.
BENTHIC FORAMINIFERA AND STABLE ISOTOPIC COMPOSITION OF GAS HYDRATE-BEARING SEDIMENTS FROM SHENHU AREA IN THE NORTHERN SOUTH CHINA SEA (2010)

The successful gas hydrate expedition from Shenhu area in the northern South China Sea,provides an opportunity to study the influence of gas hydrate methane on the benthic foraminifera and their stable isotopic composition.In this study,benthic foraminifera and their carbon isotopes in hole BY3 from the Shenhu area were reported.The results show there has no obvious distinction in benthic foraminifera assemblage composition between gas hydrate-bearing sediments and non-gas hydrate-bearing sediments.The carbon stable isotope analyses of species(Uvigerina spp.,Cibicides spp.and Oridorsalis spp.)reveal a distinction in foraminifera between gas hydrate-bearing sediments and non-gas hydrate-bearing sediments.Uvigerina spp.,Cibicides spp.and Oridorsalis spp.collected from gas hydrate-bearing sediments exhibit highly variable and strongly depleted δ13C values,with values as-1.61‰,-0.79‰ and-1.80‰ respectively;and mean values are-0.88‰,-0.27‰ and-1.04‰ respectively from non-gas hydrate-bearing sediments.The extremely negative δ13C values of Uvigerina spp.and Oridorsalis spp.are-1.83‰ and-2.29‰ respectively,which occurred in gas hydrate-bearing sediments.The studies imply that the high carbon isotopic excursion were affected by gas hydrate methane.
Treatment of Achalasia in Chagas' Disease with Botulinum Toxin (1995)

To the Editor: Chagas' disease, which is common in Brazil, often involves the esophageal neural plexus, resulting in clinical, manometric, and histologic findings resembling those of achalasia. The...
Laser Emission of a Neodymium Salt Dissolved in POCl3 (1968)

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