gebhart/patrepeval huggingface dataset:
Application of the subspace method to speech recognition (2005)

In this paper, the subspace method of pattern recognition, in which method classification is decided by the largest projection of an unknown pattern vector onto subspaces corresponding to different classes, is applied to the recognition of continuous Finnish speech. Classification is based on phonemic power spectra produced by an analog filter bank. When compared, e.g., with the nearest-neighbor method and the method of direction cosines, the advantages of the subspace method are an improved stability of classification and a more balanced total classification accuracy of the different phonemic classes with respect to their relative frequencies of occurrence. The efficient spanning of the subspaces as well as their mutual orthogonalization are discussed. Furthermore, the close relationship between the phonemic labeling and segmentation when using the subspace method is pointed out.
Refractive Indices of Infrared Optical Materials and Color Correction of Infrared Lenses* (1962)

The senior author’s interpolation formula for computing the dispersion of glass has been appropriately modified and applied to infrared materials. Indices of refraction for 14 optical materials that are suitable for practical refracting systems have been fitted by the modified formula and have been tabulated at increments of 0.5 μ for the useful transmittance range of each material. The method of applying the dispersion formula is discussed and is illustrated by the design of two three-element superachromats corrected for the region of 2.0–5.0 μ.
Two-photon-absorbed near-infrared photopolymerization for three-dimensional microfabrication (1998)

We present three-dimensional (3-D) microstructures fabricated from photopolymerizable resin with a resolution of 0.62 /spl mu/m. The method used to fabricate such small structures has been developed using a femto-second-pulsed near-infrared (IR) laser. Structures such as microcoils and microtubes are presented which demonstrate the effectiveness of our method. In this method, a two-photon absorption process is successfully utilized to confine the solidification of photopolymerizable resin to the focused spot of the laser, which is possible due to the quadratic dependence of the two-photon absorption rate on light intensity. The experimental system, experimental conditions, and related issues for this novel method of photopolymerization are also discussed.
[UV-irradiation of the blood in the treatment of polycystic ovary syndrome]. (1993)

Effect of extracorporeal UV irradiation of the blood on the clinical picture and hormonal profile of patients with the polycystic ovaries syndrome was under study. 119 women were administered 582 sessions, and in 54 of these the results were followed up for 1-25 months. A good clinical effect was achieved in 88.9% of these cases, it consisted in recovery of the cycle rhythm (70.7%), pregnancy (29.2%), reduction of hirsutism manifestations (19.04%), decrease of galactorrhea (41.7%), cessation or alleviation of headaches (86.2%), body mass reduction (40%), arterial pressure normalization (43.8%). Well-being of the majority of women was improved by therapy. 17-ketosteroids excretion normalized and persisted normal in a month after the treatment. Blood LH level and the LH/FSH ratio significantly reduced in those in whom these values were elevated in disease. Elimination of hyperandrogenism and a trend to normalization of gonadotropin secretion, resulting from extracorporeal UV irradiation of the blood, indicate that such treatment modality is pathogenetically grounded and justify its use in the treatment of women with the polycystic ovaries syndrome.
Sensor Fusion Applied to Autonomous Aerial Refueling (2008)

DOI: 10.2514/1.34589 A methodology for performing sensor fusion using differential Global Positioning System receivers, inertial measurements, wireless communication, and electro-optical measurements is presented. An estimation structure basedonanextendedKalman filterisdevelopedtoestimate thepreciserelativeposition,velocity,andattitudeoftwo aircraft flying incloseproximity. Theprojectisfocusedonthedevelopmentofthismethodologyforautomaticaerial refueling in which a boom control system uses the output of the sensor fusion to guide the boom into the receiver receptacle. Results from a real-time, hardware-in-the-loop demonstration are presented which show estimator performance and feedback control capability on a scaled model.
Abstract 5776: Discovery of AMG 900, a highly selective, orally bioavailable inhibitor of aurora kinases with efficacy in preclinical antitumor models and activity against multidrug-resistant cells (2010)

Abstract The aurora family of serine/threonine kinases (Aurora-A, -B, -C) regulate cell-cycle progression in mammalian cells. Whereas aurora kinase C function appears restricted to meiosis in males, aurora kinases A and B are essential for proper chromosome congression, segregation, and cytokinesis during mitosis. Aurora kinases A and B have been implicated in tumorigenesis, with overexpression levels correlating to clinical staging of cancers and poor prognosis. Thus, these mitotic kinases have become the subject of much interest as targets for anticancer therapy. N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-phenyl-1-phthalazinamine was a key aurora kinase inhibitor lead, possessing oral bioavailability in rats that was lacking in the anthranilamide compounds from which it was derived. This phthalazine compound possessed a key feature that was deemed important to maintain in a clinical candidate: potency against a model multidrug resistant (MDR) cell line (MES-SA Dx5) commensurate with its activity against a cell line that does not overexpress P-gp (HeLa). Improved in vivo potency was desired, as measured by suppression of the phosphorylation of the aurora kinase B substrate Histone H3 on Ser10 six hours after dosing. SAR from targeting this improvement in in vivo activity uncovered a delicate balance between protein binding, pharmacokinetic parameters, and cell potency in MES-SA Dx5 cells. AMG 900 was identified as a suitable candidate for clinical development based on its low single digit nanomolar potency against MDR cell lines, robust PD response (with complete suppression of Histone H3 phosphorylation at six hours), and high selectivity against other kinases. Oral administration of AMG 900 at a well-tolerated dose of 4 mg/kg BID inhibited tumor growth (83% TGI; p &lt; 0.0001) in an HCT116 xenograft model. AMG 900 is currently undergoing phase 1 clinical evaluation in patients with advanced solid tumors. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 5776.
An Aptamer‐Based Protein Biosensor by Detecting the Amplified Impedance Signal (2006)

Abstract A label‐free electrochemical impedance based protein biosensor was introduced by using aptamer as recognition tool. Our sensing protocol utilizes the affinity interaction between the thrombin and the self‐assembled DNA aptamer on gold electrode. This specific interaction increases the electrode interfacial electronic transfer resistance. The resistance signal is then “amplified” by using guanidine hydrochloride to denature the captured thrombin for increasing the hydrated radius of the thrombin, consequently blocking the electron transfer from solution to electrode. The sensor sensitivity is improved using this strategy and as low as 1.0×10 −14 mol L −1 thrombin (enzymatic activity 10 U/mg) can be detected out.
Spin and wavelength multiplexed nonlinear metasurface holography (2016)

Metasurfaces, as the ultrathin version of metamaterials, have caught growing attention due to their superior capability in controlling the phase, amplitude and polarization states of light. Among various types of metasurfaces, geometric metasurface that encodes a geometric or Pancharatnam-Berry phase into the orientation angle of the constituent meta-atoms has shown great potential in controlling light in both linear and nonlinear optical regimes. The robust and dispersionless nature of the geometric phase simplifies the wave manipulation tremendously. Benefitting from the continuous phase control, metasurface holography has exhibited advantages over conventional depth controlled holography with discretized phase levels. Here we report on spin and wavelength multiplexed nonlinear metasurface holography, which allows construction of multiple target holographic images carried independently by the fundamental and harmonic generation waves of different spins. The nonlinear holograms provide independent, nondispersive and crosstalk-free post-selective channels for holographic multiplexing and multidimensional optical data storages, anti-counterfeiting, and optical encryption.
On-line microwave monitor for solid concentration in coal-water slurries. Final report (1981)

The feasibility of utilizing microwave techniques to measure coal concentration and linear flow velocity of coal-water slurries was investigated. The technique consisted of utilizing the slurry pipe as a circular waveguide and monitoring the frequency corresponding to the onset of power transmission in the waveguide (cut-off frequency) between recessed antennae. The cut-off frequency depends upon the dielectric constant of the slurry filling the pipe segment which is a function of the volume fraction of coal in the slurry. The technique was tested in 3/4 in. and 1-1/2 in. pipes using slurries containing 40 to 65% by weight Utah bituminous coal. The precision of the method was +-0.2% of the absolute value. The method was found to be independent of the direction of coal flow, particle size distribution, flow velocity above 0.15 m/s to the highest velocity tested, 3.8 m/s. The temperature dependence of the method was predictable from the measured dielectric constants of the slurries, and could therefore be correctable. Measurement variation with temperature was +-0.5% between 22/sup 0/C and 50/sup 0/C. Linear flow velocities could be determined by cross correlation of the noise from two microwave test sections separated by a known distance, and approximate values of the flowmore » rate and the flow/no flow condition could be determined from the noise spectrum of a single test section.« less
Stereoselective Synthesis of Highly Functionalized C-Glycosides based on Acetal [1,2] and [1,4] Wittig Rearrangements (2000)

Two types of highly functionalized C-glycosides were stereoselectively synthesized from an ethynylvinylmethanol-derived O-glycoside in one step through acetal Wittig rearrangements (see scheme). The [1,2] Wittig rearrangement affords the 1β-C-glycoside that has contiguous quarternary chiral centers at the C1 and C1′ positions, while the [1,4] Wittig rearrangement has been used for the first time in the synthesis of C-glycosides.
ChemInform Abstract: Fullerene C60 and C70 Photosensitized Oxygenation of Olefins. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Interpreting methane variations in the past two decades using measurements of CH <sub>4</sub> mixing ratio and isotopic composition (2011)

Abstract. The availability δ13C-CH4 measurements from atmospheric samples has significantly improved in recent years, which allows the construction of time series spanning up to about 2 decades. We have used these measurements to investigate the cause of the methane growth rate decline since 1980, with a special focus on the period 1998–2006 when the methane growth came to a halt. The constraints provided by the CH4 and δ13C-CH4 measurements are used to construct hypothetical source and sink scenarios, which are translated into corresponding atmospheric concentrations using the atmospheric transport model TM3 for evaluation against the measurements. The base scenario, composed of anthropogenic emissions according to EDGAR 4.0, constant emissions from natural sources, and a constant atmospheric lifetime, overestimates the observed global growth rates of CH4 and δ13C-CH4 by, respectively, 10 ppb yr−1 and 0.02‰ yr−1 after the year 2000. It proves difficult to repair this inconsistency by modifying trends in emissions only, notably because a temporary reduction of isotopically light sources, such as natural wetlands, leads to a further increase of δ13C-CH4. Furthermore, our results are difficult to reconcile with the estimated increase of 5 Tg CH4 yr−1 in emissions from fossil fuel use in the period 2000–2005. On the other hand, we find that a moderate (less than 5% per decade) increase in the global OH concentration can bring the model in agreement with the measurements for plausible emission scenarios. This study demonstrates the value of global monitoring of methane isotopes, and calls for further investigation into the role OH and anthropogenic emissions to further improve our understanding of methane variations in recent years.
Composite Structure Repair (1984)

The technology for advanced composite structure repair is presently in a developing stage. The boundaries and limitations of bolted versus bonded repairs and precured patches versus cocured in place patches and their applicability to various types of hardware has yet to be clearly established. This paper does not discuss step by step repair procedures for specific aircraft components, such as defined in repair technical orders, but rather provides general guidelines for repair concepts and discusses two repair configurations that are generic in nature; an external patch and a near flush repair and the extent to which they have been verified in the U.S. These repairs are applicable to a wide variety of light to moderately bonded (up to 25,000 lb/inch) stiffened and honeycomb sandwich structure sustaining damage over a reasonably large area (up to 100 sq. in.) Also provided are references to documents containing step by step procedures for these repair techniques and identification of organizations in the U.S. actively engaged in advanced composite structure repair.
Clinical efficacy of a herpes simplex subunit vaccine (1985)

A DNA-free herpes simplex type 2 subunit vaccine was administered to 18 volunteers without past evidence of herpes simplex type 1 (HSV 1) or herpes simplex type 2 (HSV 2) infection, to 44 patients with severe recurrent genital HSV 2 infection, and to 15 patients with severe oral type 1 HSV recurrences. The vaccine elicited both humoral and cell-mediated immunity in 97% of the subjects without past HSV infections and boosted significantly the cell-mediated immunity and antibody titers in almost all the patients with recurrent HSV 1 or HSV 2. The vaccine elicited particularly the production of complement-dependent cytotoxic antibodies in 96% of the patients with recurrent HSV 2 infections. This might, at least partly, explain the clinical efficacy of the vaccine. Indeed, we observed a significant decrease (t test, p less than 0.01) in the attack rate of the recurrences and also a significant shortening of the time needed to complete healing of the lesions (t test, p less than 0.01).
Cyberthreats under the Bed (2018)

Internet-connected toys provide an often-overlooked avenue for breaching personal data, especially of those most vulnerable. Government and private measures can minimize the risks, but responsibility for monitoring smart toy usage ultimately lies with parents.
The hydroxyphenylpyruvate dioxygenase from <i>Synechocystis</i> sp. PCC 6803 is not required for plastoquinone biosynthesis (2002)

The disruption of the Synechocystis open reading frame Deltaslr0090 encoding a gene with high homology to plant genes encoding 4-hydroxyphenylpyruvate dioxygenase results in an impairment of tocopherol biosynthesis without affecting levels of plastoquinone, carotenoids and chlorophyll as well as cell growth and photosynthesis. Our results indicate that in Synechocystis in contrast to the situation in higher plants the 4-hydroxyphenylpyruvate dioxygenase is not required for the synthesis of plastoquinone.
Resistance in the Grass Tribe Maydeae to Larvae of the Western Corn Rootworm1,2 (1971)

Journal Article Resistance in the Grass Tribe Maydeae to Larvae of the Western Corn Rootworm, Get access Terry F. Branson Terry F. Branson 3The plant species were obtained from the following persons: Dr. W. C. Galinat, University of Massachusetts, Waltham; Dr. W. R. Lnngford, Regional Plant Introduction Station, Experiment, Ga.; Dr.W. H. Skrdla, Regional Plant Introduction Station, Ames, Iowa; and Dr. D. H. Timothy, North Carolina State University, Raleigh. Their assistance is greatly appreciated. Search for other works by this author on: Oxford Academic Google Scholar Annals of the Entomological Society of America, Volume 64, Issue 4, 15 July 1971, Pages 861–863, https://doi.org/10.1093/aesa/64.4.861 Published: 15 July 1971 Article history Received: 22 January 1971 Published: 15 July 1971
Formal Framework of XML Document Schema Design (2012)

Designing “good” XML documents is a very difficult task for a database designer. Although many theories for XML database design have proposed, none of commercial design tool for XML document design has been developed to assist the XML document designer. In this paper, the authors present a formal framework of XML document design by incorporating a conceptual model of XML schema called Graph-Document Type Definition (G-DTD) with a theory of database normalization. This framework is designed as a blueprint to help the XML database designers to perform the XML document schema design quickly and accurately. The G-DTD is used to describe the structure of XML documents at the schema level. A set of normal forms for G-DTD on the basis of rules proposed by Arenas and Libkin and Lv. et al is used to provide a guideline to a well-designed schema for XML documents. They develop a prototype of XML document schema design using a Z formal specification language. Finally, using a case study, this formal specification is validated to check for correctness and consistency of the specification. Thus, this gives a confidence that the authors’ prototype can be implemented successfully to generate an automatic XML document design.
Effectiveness of anti–folate receptor β antibody conjugated with truncated <i>Pseudomonas</i> exotoxin in the targeting of rheumatoid arthritis synovial macrophages (2005)

We demonstrated the limited distribution of FRbeta-expressing cells in various tissues. The immunotoxin targeting FRbeta-expressing cells will provide a therapeutic tool for rheumatoid synovitis.
Behaviro of Substrate-Originating Si Atoms during Chemical Vapor Deposition and Subsequent Active Oxygen Annealing of Tantalum Pentoxide Film (1993)

1993 International Conference on Solid State Devices and Materials,Behaviro of Substrate-Originating Si Atoms during Chemical Vapor Deposition and Subsequent Active Oxygen Annealing of Tantalum Pentoxide Film
IDENTIFICATION OF THE GENE FOR ADULT-PLANT LEAF RUST RESISTANCE IN THATCHER (1979)

The gene for adult-plant resistance to race 9 of leaf rust (Puccinia recondita Rob. ex. Desm.) in the common wheat cultivar Thatcher (Triticum aestivum L.) was allelic to Lr22a, a gene for adult-plant leaf rust resistance previously transferred to hexaploid wheat from Aegilops squarrosa L. This gene, designated Lr22b, was linked with Tg, a gene for tenacious glumes, and W2 1 , an inhibitor of waxy foliage, both known to be on chromosome arm 2Dα and linked with Lr22a.
Percutaneous Vertebroplasty (1997)

Percutaneous vertebroplasty (PVP) with acrylic cement [polymethylmethacrylate (PMMA)]consists of injecting PMMA into vertebral bodies weakened by osseous lesions. The aim of PVP with PMMA is to obtain an antalgic effect by consolidation in destructive lesions of the spine. There are three major indications: vertebral angiomas, osteoporotic vertebral crush syndromes, and malignant vertebral tumors. Indications in vertebral angiomas only concern patients with aggressive clinical signs (severe pain or nervous compression) and/or aggressive radiological signs. Indications in osteoporotic vertebral crush syndromes only concern patients suffering from back pain related to one or two adjacent vertebral collapses resistant to medical treatment for several weeks. Indications in malignant vertebral tumors only concern patients suffering from severe back pain related to a destruction of the vertebral body, not involving the major part of the cortical bone. Complications of PVP occur essentially in patients with vertebral metastasis. In the great majority of cases, these complications heal under medical treatment. In patients with osteoporotic vertebral crush syndromes or vertebral angiomas, the complications are represented by the increase or onset of radiculalgias (in less than 1%), which disappear after local anesthetic injection.
Computer simulation of compliant motion control for a robotic arm (2003)

A hybrid position force control scheme was used to simulate the control of a two-degree-of-freedom robotic arm. The contact force between the end-effector and a surface was controlled while the end-effector moved parallel to the surface under position control. The end-effector was modeled as having passive compliance. Five simulations were performed using different levels of random noise in the force feedback loop. Stability was achieved and significant force control was maintained, despite high levels of noise in the force feedback.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>