gebhart/patrepeval huggingface dataset:
Expression of Prostaglandin D Synthase in Ovarian Cancer (2001)

Lipocalin-type prostaglandin D synthase (L-PGDS) has recently been shown to be expressed in human brain tumors and breast tumors. However, L-PGDS expression has not been investigated in ovarian cancer. The objective of this study was to determine whether L-PGDS is expressed in human ovarian cancer. Lipocalin prostaglandin D synthase mRNA was cloned and sequenced by RT-PCR. Using in situ hybridization (ISH) technique, the expression of L-PGDS mRNA in 54 ovarian cancer was investigated. Expression of L-PGDS mRNA was found in tumor cells of all various types of ovarian cancers. Patterns of staining of tumor cells varied among different histological types of ovarian cancer. Significant discrepancy between the intensity of the staining and histological types of ovarian cancer could be established (p<0.01). It is reported for the first time that the expression of mRNA of L-PGDS exists in the ovarian cancer, and is related to the cancer type. This may have significance for the progress of ovarian cancer.
End-fire Quasi-Yagi antennas with pattern diversity on LTCC technology for 5G mobile communications (2016)

We have designed two end-fire antennas on LTCC with horizontal and vertical polarizations respectively. The antennas operate at 38GHz, a potential frequency for 5G applications. The horizontally-polarized antenna provide a broadband performance about 27% and 6dB end-fire gain and the vertically-polarized one provide a 12.5% bandwidth and 5dB gain. Both antenna are integrated under a compact substrate. Excellent isolation is achieved between the nearby elements making these antennas suitable for corner elements in 5G mobile system.
A systematical study about the genus Lycopus L. (Labiatae)in Iraq (2010)

The study included gross morphology and pollen of plants – which collected during field trips , and dry ones for most specimen preserved with the Iraqi herbaria – related to the genus Lycopus L. , and to identify the unidentified species and rectify the error there in , so according to that the species L. europaeus L. only were specified for the genus . Through this work the varity L. europaeus var. glabrescens Schmidely were found at the first time , and suggested to record anew for Iraq . Pollen were of medium size, and had an ellipsoid shape in the equatorial view , and hexagonal in the polar view. The ecological and soil quality where these genus plants grows were specified , and were geographically distributed on natural Iraqi territories for each one .Plate was made from many pictures in addition to the map for geographical distribution.
Vascular Injury and Thrombotic Potential: A Note of Caution About Recombinant Factor VIIa (2007)

Postoperative hemorrhage following cardiac surgery increases morbidity, mortality, and costs. Several case reports have described the successful use of recombinant factor VIIa to decrease or stop bleeding in patients undergoing cardiac surgery. The mechanism of action of recombinant factor VIIa is thought to be increased site-specific thrombin generation by tissue factor-mediated activation of coagulation or from activated platelets. However, there have also been many reports of thrombotic complications after recombinant factor VIIa administration. Randomized clinical trials and further laboratory studies should help better clarify the efficacy, safety, cost-effectiveness, and optimal dosing of recombinant factor VIIa in the cardiac surgical setting.
Low dispersion penalty at 10 Gb/s, over 75 km, using a quantum-well-intermixed electroabsorption-modulator/widely-tunable laser transmitter (2004)

Abstract: 1OGb/s low power penalty (&lt;0.5 dB) error-free transmission was achieved through 75km using a high-performance widely-tunable EAM/laser transmitter operating under negative c h q conditions. An integration-oriented quantum-well-intermixing process was employed for the realization of these devices. a2004 Optical Society of America OCIS codes: (140.5960) Semiconductor lasers; (140.3600) Lasers, tunable; (250.5300) Photonic Integrated Circuits
Uncooled thermal imaging with thin-film ferroelectric detectors (2008)

Uncooled infrared imaging as a viable technology began in earnest when ferroelectric detectors based on bulk ceramic barium strontium titanate (BST) demonstrated NETDs less than 100mK at prices sufficiently low for commercial and consumer applications. Although the image quality generated by this technology remains unsurpassed, it has been largely supplanted by microbolometer technology, which is capable of being fabricated in substantially smaller pixel sizes, leading to smaller systems, and which is a monolithic device, resulting in a simpler fabrication process than the hybrid BST device.
Baclofen Protects Primary Rat Retinal Ganglion Cells from Chemical Hypoxia-Induced Apoptosis Through the Akt and PERK Pathways (2016)

Retinal ganglion cells (RGCs) consume large quantities of energy to convert light information into a neuronal signal, which makes them highly susceptible to hypoxic injury. This study aimed to investigate the potential protection by baclofen, a GABA<sub>B</sub> receptor agonist of RGCs against hypoxia-induced apoptosis. Cobalt chloride (CoCl<sub>2</sub>) was applied to mimic hypoxia. Primary rat RGCs were subjected to CoCl<sub>2</sub> with or without baclofen treatment, and RNA interference techniques were used to knock down the GABA<sub>B</sub>2 gene in the primary RGCs. The viability and apoptosis of RGCs were assessed using cell viability and terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assays, Hoechst staining, and flow cytometry. The expression of cleaved caspase-3, bcl-2, bax, Akt, phospho-Akt, protein kinase RNA (PKR)-like ER kinase (PERK), phospho-PERK, eIF2α, phospho-eIF2α, ATF-4 and CCAAT/enhancer-binding protein homologous protein (CHOP) were measured using western blotting. GABA<sub>B</sub>2 mRNA expression was determined using quantitative real-time polymerase chain reaction (qRT-PCR) analysis. Our study revealed that CoCl<sub>2</sub> significantly induced RGC apoptosis and that baclofen reversed these effects. CoCl<sub>2</sub>-induced reduction of Akt activity was also reversed by baclofen. Baclofen prevented the activation of the PERK pathway and the increase in CHOP expression induced by CoCl<sub>2</sub>. Knockdown of GABA<sub>B</sub>2 and the inactivation of the Akt pathway by inhibitors reduced the protective effect of baclofen on CoCl<sub>2</sub>-treated RGCs. Taken together, these results demonstrate that baclofen protects RGCs from CoCl<sub>2</sub>-induced apoptosis by increasing Akt activity and by suppressing the PERK pathway and CHOP activation.
Thermal Stability of Tungsten-Based Schottky Contacts to N-Type ZnO (2006)

Abstract not Available.
Degradation versus Aggregation of Misfolded Maltose-binding Protein in the Periplasm of Escherichia coli (1998)

The periplasmic fates of misfolded MalE31, a defective folding mutant of the maltose-binding protein, were determined by manipulating two cellular activities affecting the protein folding pathway in host cells: (i) the malEp promoter activity, which is controlled by the transcriptional activator MalT, and (ii) the DegP and Protease III periplasmic proteolytic activity. At a low level of expression, the degradation of misfolded MalE31 was partially impaired in cells lacking DegP or Protease III. At a high level of expression, misfolded MalE31 rapidly formed periplasmic inclusion bodies and thus escaped degradation. However, the manipulated host cell activities did not enhance the production of periplasmic, soluble MalE31. A kinetic competition between folding, aggregation, and degradation is proposed as a general model for the biogenesis of periplasmic proteins.
Interaction of DNA Oligomers with Cationic Lipidic Monolayers:  Complexation and Splitting (2007)

Interactions of native DNA with octadecylamine (ODA) and hexadecymdimethylammonium bromide (HTAB) monolayers at the air/water interface were studied by pi-A isotherms, ellipsometry, and X-ray reflectivity. We show that the microscopic structure of ODA-DNA complexes is definitely consistent with a single-stranded form for DNA. On the contrary, with HTAB, DNA complexes in its native form. The crucial difference in the behavior of these two fairly similar lipids is due to the presence of the amine group in ODA. These results should be relevant to applications such as DNA chips and sensors.
Enhancing activity recognition by fusing inertial and biometric information (2011)

Activity recognition is an active research field nowadays, as it enables the development of highly adaptive applications, e.g. in the field of personal health. In this paper, a light high-level fusion algorithm to detect the activity that an individual is performing is presented. The algorithm relies on data gathered from accelerometers placed on different parts of the body, and on biometric sensors. Inertial sensors allow detecting activity by analyzing signal features such as amplitude or peaks. In addition, there is a relationship between the activity intensity and biometric response, which can be considered together with acceleration data to improve the accuracy of activity detection. The proposed algorithm is designed to work with minimum computational cost, being ready to run in a mobile device as part of a context-aware application. In order to enable different user scenarios, the algorithm offers best-effort activity estimation: its quality of estimation depends on the position and number of the available inertial sensors, and also on the presence of biometric information.
Single image portrait relighting (2019)

Lighting plays a central role in conveying the essence and depth of the subject in a portrait photograph. Professional photographers will carefully control the lighting in their studio to manipulate the appearance of their subject, while consumer photographers are usually constrained to the illumination of their environment. Though prior works have explored techniques for relighting an image, their utility is usually limited due to requirements of specialized hardware, multiple images of the subject under controlled or known illuminations, or accurate models of geometry and reflectance. To this end, we present a system for portrait relighting : a neural network that takes as input a single RGB image of a portrait taken with a standard cellphone camera in an unconstrained environment, and from that image produces a relit image of that subject as though it were illuminated according to any provided environment map. Our method is trained on a small database of 18 individuals captured under different directional light sources in a controlled light stage setup consisting of a densely sampled sphere of lights. Our proposed technique produces quantitatively superior results on our dataset's validation set compared to prior works, and produces convincing qualitative relighting results on a dataset of hundreds of real-world cellphone portraits. Because our technique can produce a 640 × 640 image in only 160 milliseconds, it may enable interactive user-facing photographic applications in the future.
AppTrends: A graph-based mobile app recommendation system using usage history (2015)

With the advent of smartphones, mobile phones have evolved from a simple communication tool to a multipurpose device that affects every aspect of our daily life. The expansion of the mobile application market has made it difficult for smartphone users to find applications that fit their needs. Most prior research on application recommendation provides a limited solution to the problem of application overload. These recommendation techniques, developed outside of the mobile environment, have a number of limitations such as cold start problem and domain disparity. In this paper, we propose AppTrends, which incorporates a graph-based technique for application recommendation in the Android OS environment. Our experiment results obtained from the field usage record of over 4 million applications clearly show that the proposed graph-based recommendation model is more accurate than the Slope One Model.
GaN-based monolithic power integrated circuit technology with wide operating temperature on polarization-junction platform (2015)

Polarization junction platforms have high-density 2D hole gas (2DHG) and 2D electron gas (2DEG) respectively induced by negative and positive polarization charges in undoped GaN/AlGaN/GaN double heterostructures. Sheet resistance measurements in a wide temperature range (6-460 K) revealed that 2DHG and 2DEG resistances were monotonically enhanced with the temperature reduction. On the platform, monolithic operations of GaN-based devices including high-voltage n-channel (N-ch) transistors, N-ch Schottky diodes, low-voltage N-ch transistors and p-channel transistors has been demonstrated.
The broad applicability of the disk laser principle: from CW to ps (2009)

The quasi two-dimensional geometry of the disk laser results in conceptional advantages over other geometries. Fundamentally, the thin disk laser allows true power scaling by increasing the pump spot diameter on the disk while keeping the power density constant. This scaling procedure keeps optical peak intensity, temperature, stress profile, and optical path differences in the disk nearly unchanged. The required pump beam brightness - a main cost driver of DPSSL systems - also remains constant. We present these fundamental concepts and present results in the wide range of multi kW-class CW-sources, high power Q-switched sources and ultrashort pulsed sources.
An environmental energy harvesting framework for sensor networks (2003)

Energy constrained systems such as sensor networks can increase their usable lifetimes by extracting energy from their environment. However, environmental energy will typically not be spread homogeneously over the spread of the network. We argue that significant improvements in usable system lifetime can be achieved if the task allocation is aligned with the spatio-temporal characteristics of energy availability. To the best of our knowledge, this problem has not been addressed before. We present a distributed framework for the sensor network to adaptively learn its energy environment and give localized algorithms to use this information for task sharing among nodes. Our framework allows the system to exploit its energy resources more efficiently, thus increasing its lifetime. These gains are in addition to those from utilizing sleep modes and residual energy based scheduling mechanisms. Performance studies for an experimental energy environment show up to 200% improvement in lifetime.
Experiences in separation of residual carbon in coal fly ash by grinding and air classification (1994)

-Several kinds of coal fly ash produced at a coal-firing power station of KYUSHU ELECTRIC POWER Co., Inc., JAPAN, were studied for the purpose of utilization of their coarser parts. The coarser part of the fly ash collected by an air classification contained a relatively larger amount of residual carbon particles compared with the finer part. After a detail investigation on the grindability of those residual carbons and the grinding phenomena in the classification process, a new type of air classifier was designed, the rotator of which classifier was provided with a number of pins in order to encourage grinding function. Due to the difference of grindability between carbon and fly ash, those grinding pins ground large and fragile carbon particles to a higher fineness, thereby reducing carbon content of the coarser part. Achieved were carbon reduction rates of 20 to 50% in the coarser part with the new classifier.
The abundance and organization of polypeptides associated with antigens of the Rh blood group system (1991)

Twelve murine monoclonal antibodies, which react with human red cells of common Rh phenotype but give weak or negative reactions with Rh null erythrocytes, were used in quantitative binding assays and competitive binding assays to investigate the abundance and organization of polypeptides involved in the expression of antigens of the Rh blood group system. Antibodies of the R6A-type (R6A, BRIC-69, BRIC-207) and the 2D10-type (MB-2D10, LA18.18, LA23.40) recognize related structures and 100,000-200,000 molecules of each antibody bind maximally to erythrocytes of common Rh phenotype. Antibodies of the BRIC-125 type (BRICs 32, 122, 125, 126, 168, 211) recognize structures that are unrelated to those recognized by R6A-type and 2D10-type antibodies and between 10,000 and 50,000 antibody molecules bind maximally to erythrocytes of the common Rh phenotype. The binding of antibodies of the R6A-type and the 2D10-type, but not of antibodies of the BRIC-125-type could be partially inhibited by human anti-D antibodies (polyclonal and monoclonal) and a murine anti-e-like antibody. These results are consistent with evidence (Moore & Green 1987; Avent et al., 1988b) that the Rh blood group antigens are associated with a complex that comprises two groups of related polypeptides of M(r) 30,000 and M(r) 35,000-100,000, respectively, and suggest that there are 1-2 x 10(5) copies of this complex per erythrocyte. The polypeptide recognized by antibodies of the BRIC-125 type is likely to be associated with this complex.
Analogs of tetrahydrofolic acid. XII. On the relative contribution by the 2‐amino and 4‐hydroxy groups of 2‐amino‐5‐(3‐anilinopropyl)‐6‐methyl‐4‐pyrimidinol to inhibition of folic reductase and thymidylate synthetase (1964)

Abstract The structure of 2‐amino‐5‐(3‐anilinopropyl)‐6‐methyl‐4‐pyrimidinol (II), an inhibitor of both dihydrofolic reductase and thymidylate synthetase, has been modified by replacement of the 2‐amino group by hydrogen or the 4‐hydroxyl group by hydrogen, mercapto or amino. Enzymic evaluation showed that 5‐(3‐anilinopropyl)‐2,4‐diamino‐6‐methyl‐pyrimidine was a 170‐fold more effective inhibitor of dihydrofolic reductase than thymidylate synthetase. This specificity is due to the fact that replacement of the 4‐hydroxyl group of II with 4‐amino enhances binding to dihydrofolic reductase by 350‐fold, but binding to thymidylate synthetase is unchanged. No significant cross‐over specificity was noted with the six compounds studied. Replacement of the 4‐hydroxyl group of II by hydrogen gave a compound (XVII) that was a slightly more effective inhibitor of dihydrofolic reductase than II, but was slightly less effective on thymidylate synthetase. Binding to dihydrofolic reductase and to thymidylate synthetase could be increased by 17‐fold and 5‐fold, respectively, by replacement of the 4‐hydroxyl group of II by 4‐mercapto (XVI). It was concluded that the mode of binding in the N‐3 and 4‐hydroxyl region of II was not the same for the two enzymes. Synthesis of the 2‐amino‐, the 4‐hydroxy‐ and the 4‐mercaptopyrimidyl analogs of II are described. Also described are the partial purification of and assays for dihydrofolic reductase and thymidylate synthetase by procedures more familiar to the organic chemist.
Stability studies of the effect of crosslinking on hydrochlorothiazide release. (2009)

The aim of this study was to determine the changes in the in vitro drug release from cross-linked hard gelatin capsules containing a water-insoluble drug. An immediate release hydrochlorothiazide (HCTZ) capsule formulations containing drug, lactose, starch 1500 were prepared and exposed to accelerated stability study (40°C/ambient RH, 40°C/60% RH, 40°C/75% RH, and 40°C/90% RH) in a closed dark bottles for 4 weeks. Notable decrease in drug dissolution was observed after the 4 weeks in all humidity conditions as compared with freshly prepared capsules. In an attempt to overcome capsule cross-linking, glycine alone, citric acid alone and both glycine and citric acid were added to the prepared formulations. In all humidity conditions, addition of glycine alone or citric acid alone did not affect the decrease in dissolution profile. On the other hand, addition of both glycine and citric acid together was found to prevent capsule cross-linking completely. Fourier transfer infra-red (FTIR) spectroscopy and differential scanning calorimetry (DSC) were performed on blank capsules and after storage for 4 weeks to identify the physicochemical changes in drug and other capsule components hence its effect on dissolution.
Numerical simulation of attenuated wavefields using a Pade approximant method (1984)

Realistic anelastic attenuation laws are usually formulated as convolution operators, but this representation is intractable for time-domain synthetic seismogram methods such as the finite difference method. An approach based on Padé approximants provides a convenient, accurate reformulation of general anelastic laws in differential form. The resulting differential operators form a uniformly convergent sequence of increasing order in the time derivative, and all are shown to be causal, stable and dissipative. In the special case of frequency-independent Q, all required coefficients for the operators are obtained in closed form in terms of Legendre polynomials. Low-order approximants are surprisingly accurate. Finite-difference impulse responses for a plane wave in a constant-Q medium, calculated with the fifth-order convergent, are virtually indistinguishable from the exact solution. The formulation is easily generalized to non-scalar waves. Moreover, this method provides a framework for incorporating amplitude-dependent attenuation into numerical simulations.
Detection of adenoviruses in stools from healthy persons and patients with diarrhea by two‐step polymerase chain reaction (1992)

The use of the polymerase chain reaction (PCR) for detection of human adenoviruses in diluted stool samples was investigated. Two sets of nested primers, including primers specific for the hexon-coding region and for the E1B region of enteric adenoviruses (EAd), were assessed by two-step amplification. The primers constitute two different PCR systems designed for the detection of adenoviruses belonging to all six subgenera (A-F), and the two EAds Ad40 and Ad41, respectively. In a two-step PCR mediated amplification a single virus particle was detected when the two sets of general hexon primers or EAd specific primers were used. Earlier results from PCR detection of adenoviruses in stool from children suffering from diarrhea gave indications that adenovirus particles are commonly shed in stools without being identified as the cause of illness [Allard et al.: Journal of Clinical Microbiology 28:2659-2667, 1990]. Therefore, the general and the EAd specific PCR assays were assessed on 150 stool specimens from three groups including 50 healthy children, 50 healthy adults, and 50 adults suffering from diarrhea. When the two sets of general hexon primers were used, 25 of the 50 specimens from the healthy children (mean age 21 months) were found positive by two-step PCR amplification. Nine of the 50 specimens from the healthy adults (mean age 32 years) were found positive whereas 12 of the 50 specimens from sick adults (mean age 31 years) gave amplification products, using the two sets of general hexon primers in a nested fashion. None of the 150 specimens were found to be positive by two-step PCR amplification using the two sets of EAd-specific primers.(ABSTRACT TRUNCATED AT 250 WORDS)