gebhart/patrepeval huggingface dataset:
Multi-Dimensional Password Generation Technique for Accessing Cloud Services (2012)

Cloud computing is drastically growing technology which provides an on-demand software, hardware, infrastructure and data storage as services. This technology is used worldwide to improve the business infrastructure and performance. However, to utilize these services by intended customer, it is necessary to have strong password authentication. At present, cloud password authentication can be done in several ways, such as, textual password, graphical and 3D password. In this paper, we are proposing the strong password generation technique by considering multiple input parameters of cloud paradigm referred as a multidimensional password. This paper presents the multidimensional password generation technique along with architecture, sequence diagrams, algorithms and typical user interfaces. At the end, we derive the probability of breaking our authentication system.
Business Network Transformation: Strategies to Reconfigure Your Business Relationships for Competitive Advantage (2009)

In order to defend themselves against commoditization and disruptive innovation, leading companies are now gaining competitive advantage through networked business models and tapping into talent from outside their company. Rather than implementing rigid built-to-last processes, organizations are now constructing more fluid built-to-adapt networks in which each member focuses on its differentiation and relies increasingly on its partners, suppliers, and customers to provide the rest. With contributions by the biggest names in business network transformation, this book offers cutting edge research and an in-depth exploration of critical topics such as customer value, supply networks, product leadership, global processes, operations, innovation, relationship management, and IT. The book also provides practical guidance for successfully engaging in BNT, and is filled with illustrative case studies from some of the worlds largest and most successful companies. It contains the vital information business leaders need to enable their companies to deliver faster innovation to customers at lower cost by sharing investments, assets, and ideas across their business networks. An essential resource for all business leaders, Business Network Transformation shows how to transform any business network to achieve competitive advantage and increase the bottom line. Contributors include Geoffrey Moore, Philip Lay, Marco Iansiti, Mohan Sawhney, Ranjay Gulati, David Kletter, Venkat Venkatraman, John Hagel III, John Seely Brown, Gautam Kasthurirangan, Randall Russell, Henry Chesbrough, Jeffrey Dyer, and Andrew McAfee.
Engineering end-to-end IP resilience using resilience-differentiated QoS (2002)

Network resilience is becoming a key issue in the design of IP-based multimedia and multiservice networks. The current discussion about IP network resilience centers around MPLS-based recovery mechanisms. Any well designed recovery strategy has to take into account the different resilience requirements of the single traffic flows in order to avoid excessive usage of bandwidth for standby links. Faced with multiple recovery options, an ISP or NSP must decide which flows to protect to what extent against network failures. In this article an extension to existing quality of service (QoS) architectures is presented that integrates the signaling of resilience requirements with the traditional QoS signaling. We refer to this extended QoS model as resilience-differentiated QoS (RD-QoS). At the border of MPLS domains, the resilience requirements can then be directly mapped to the appropriate MPLS recovery options. A traffic engineering process for the provisioning of the resilience classes is introduced, and a case study demonstrates the significant network capacity savings achievable via this approach.
Autocrine stimulation of TNF-alpha mRNA expression in HL-60 cells. (1987)

We have employed a human promyelocytic leukemic cell line, HL-60, to investigate the conditions that regulate TNF-alpha gene expression in vitro. Using a cloned TNF-alpha specific cDNA probe, we show by Northern blot analysis that TNF-alpha mRNA rapidly accumulates in HL-60 cells following treatment with phorbol myristate acetate (PMA). TNF-alpha mRNA levels peak at 1-2 hours and then decline to base-line levels within 8 hours. TNF-alpha protein levels as detected in the supernatants of PMA-stimulated HL-60 cells peak at 2 hours and decline within 24 hours. Cytokines of recombinant source like interferon-alpha and -gamma, and, more intruigingly, TNF-beta as well as TNF-alpha itself are also able to induce transient TNF-alpha mRNA expression in HL-60 cells. In the presence of a protein kinase inhibitor, neither PMA nor any of the cytokines used are able to induce TNF-alpha mRNA accumulation, indicating that protein kinases may be crucially involved in signal transduction leading to activation of the TNF-alpha gene. The data presented provide new insights into the control of TNF-alpha gene expression suggesting regulatory functions of T- and B-cell derived lymphokines as well as a TNF-alpha-mediated positive feedback mechanism.
Synthesis of 4-Methyl-1,2,3-thiadiazole Derivatives via Ugi Reaction and Their Biological Activities (2009)

The Ugi reaction is a green and rapid one-pot reaction for lead derivation. To develop novel candidate pesticides with diverse biological activities, two series of 4-methyl-1,2,3-thiadiazole derivatives containing active substructures of 3-chloro-4-methylphenyl or 3-fluoro-4-methylphenyl, respectively, were rationally designed and synthesized via Ugi reaction according to the principle of combinations of bioactive substructures. All of the structures of newly synthesized compounds were confirmed by proton nuclear magnetic resonance and high-resolution mass spectrometry. Biological activities of the target compounds including fungicide activity, antivirus activity in vitro and in vivo, and systemic acquired resistance were evaluated systematically. The results indicated that derivatives containing 3-(trifluoromethyl)phenyl and 2-methylphenyl possessed a potential wide spectrum of fungicidal activity. Derivatives containing 3-(trifluoromethyl)phenyl and 4-hydroxyphenyl possessed good potential direct antivirus activities against tobacco mosaic virus (TMV) in vitro, and the replacement of Cl atom by F atom improved their direct inhibition activities against TMV in vitro. Derivatives containing phenyl, 2-(trifluoromethyl)phenyl, 3-(trifluoromethyl)phenyl, 3-nitrophenyl, 4-nitrophenyl, 2-methylphenyl, and 4-hydroxyphenyl possessed good potential bioactivities in vivo including protection, inactivation, curative, and induction activities against TMV. These studies indicate that the newly synthesized 4-methyl-1,2,3-thiadiazole derivatives possessed good potential bioactivities, and a combination of bioactive substructures via Ugi reaction was an effective way to find bioactive compounds for novel pesticide development.
Insulin-like growth factor I/somatomedin C: a potent inducer of oligodendrocyte development. (1986)

Cell cultures established from cerebrum of 1-day-old rats were used to investigate hormonal regulation of the development of oligodendrocytes, which synthesize myelin in the central nervous system. The number of oligodendrocytes that developed was preferentially increased by insulin, or by insulin-like growth factor I (IGF-I), also known as somatomedin C. High concentrations (5 micrograms/ml) of insulin were required for substantial induction of oligodendrocyte development, whereas only 3.3 ng of IGF-I per ml was needed for a 2-fold increase in oligodendrocyte numbers. At an IGF-I concentration of 100 ng/ml, oligodendrocyte numbers were increased 6-fold in cultures grown in the presence of 10% fetal bovine serum, or up to 60-fold in cultures maintained in serum-free medium. IGF-I produced less than a 2-fold increase in the number of nonoligodendroglial cells in the same cultures. Type I IGF receptors were identified on oligodendrocytes and on a putative oligodendrocyte precursor cell population identified by using mouse monoclonal antibody A2B5. These results indicate that IGF-I is a potent inducer of oligodendrocyte development and suggest a possible mechanism based on IGF deficiency for the hypomyelination that results from early postnatal malnutrition.
Expression of activation‐induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis (2006)

Activation-induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression of AID has been implicated in the immunopathological phenotype of human B-cell malignancies. Notably, we found that the transgenic mice overexpressing AID developed lung adenocarcinoma and hepatocellular carcinoma (HCC), suggesting that ectopic expression of AID can lead to tumorigenesis in epithelial tissues as well. To examine the involvement of AID in the development of human HCC, we analyzed the AID expression and its correlation with mutation frequencies of the p53 gene in liver tissues from 51 patients who underwent resection of primary HCCs. The specific expression, inducibility by cytokine stimulation and mutagenic activity of AID were investigated in cultured human hepatocytes. Only trace amounts of AID transcripts were detected in the normal liver; however, endogenous AID was significantly upregulated in both HCC and surrounding noncancerous liver tissues with underlying chronic hepatitis or liver cirrhosis (p < 0.05). Most liver tissues with underlying chronic inflammation with endogenous AID upregulation already contained multiple genetic changes in the p53 gene. In both hepatoma cell lines and cultured human primary hepatocytes, the expression of AID was substantially induced by TGF-beta stimulation. Aberrant activation of AID in hepatocytes resulted in accumulation of multiple genetic alterations in the p53 gene. Our findings suggest that the aberrant expression of AID is observed in human hepatocytes with several pathological settings, including chronic liver disease and HCC, which might enhance the genetic susceptibility to mutagenesis leading to hepatocarcinogenesis.
Exciton Recycling in Graded Gap Nanocrystal Structures (2004)

We propose a cascaded energy transfer structure made of semiconductor nanocrystals. Funnel-like band gap profiles are realized applying layer-by-layer assembly to CdTe nanocrystals of distinct sizes. Optical excitations efficiently transfer along the band gap gradient and are finally captured by the largest nanocrystals. The photoluminescence yield from the center layer is surprisingly high. The stepwise passing on of excitation energy avoids hot carriers, and the funnel structure recycles otherwise trapped and lost electron−hole pairs.
Gemfibrozil, a Lipid-lowering Drug, Increases Myelin Genes in Human Oligodendrocytes via Peroxisome Proliferator-activated Receptor-β (2012)

An increase in CNS remyelination and a decrease in CNS inflammation are important steps to halt the progression of multiple sclerosis. Earlier studies have shown that gemfibrozil, a lipid-lowering drug, has anti-inflammatory properties. The current study identified another novel property of gemfibrozil in stimulating the expression of myelin-specific genes (myelin basic protein, myelin oligodendrocyte glycoprotein, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, and proteolipid protein (PLP)) in primary human oligodendrocytes, mixed glial cells, and spinal cord organotypic cultures. Although gemfibrozil is a known activator of peroxisome proliferator-activated receptor-α (PPAR-α), we were unable to detect PPAR-α in either gemfibrozil-treated or untreated human oligodendrocytes, and gemfibrozil increased the expression of myelin genes in oligodendrocytes isolated from both wild type and PPAR-α(-/-) mice. On the other hand, gemfibrozil markedly increased the expression of PPAR-β but not PPAR-γ. Consistently, antisense knockdown of PPAR-β, but not PPAR-γ, abrogated the stimulatory effect of gemfibrozil on myelin genes in human oligodendrocytes. Gemfibrozil also did not up-regulate myelin genes in oligodendroglia isolated from PPAR-β(-/-) mice. Chromatin immunoprecipitation analysis showed that gemfibrozil induced the recruitment of PPAR-β to the promoter of PLP and myelin oligodendrocyte glycoprotein genes in human oligodendrocytes. Furthermore, gemfibrozil treatment also led to the recruitment of PPAR-β to the PLP promoter in vivo in the spinal cord of experimental autoimmune encephalomyelitis mice and suppression of experimental autoimmune encephalomyelitis symptoms in PLP-T cell receptor transgenic mice. These results suggest that gemfibrozil stimulates the expression of myelin genes via PPAR-β and that gemfibrozil, a prescribed drug for humans, may find further therapeutic use in demyelinating diseases.
Attraction of<i>Aedes aegypti</i>(L.): responses to human arms, carbon dioxide, and air currents in a new type of olfactometer (1969)

A new type of olfactometer was designed to study the responses of mosquitos to various stimuli. Hosts could be displayed downwind as well as upwind from the mosquitos, and two hosts could be displayed simultaneously, one upwind from the other. Responses to radiations, if any, and to odours could be measured. Mosquitos were not attracted downwind to an arm displayed within 61 cm., even when they were stimulated by CO 2 (under an incident illumination of about 10 foot-candles). About half the mosquitos showed a positive anemotactic response ( i.e. , they left the end downwind compartment in which they were released) in a current of room air, which undoubtedly contained human emanations. Only 15 per cent, responded to filtered air. Carbon dioxide caused no increase in response to filtered air but increased the number responding to room air (76 per cent, left the end down-wind compartment). Equal numbers of mosquitos responded to an arm displayed upwind in room air and in filtered air, i.e. , about 83 per cent, left the end compartment. Carbon dioxide caused no increase in the number of mosquitos responding to an arm but increased the number responding to attenuated emanations from an arm. A repellent (deet) eliminated most of the response to an arm; the addition of carbon dioxide increased upwind flight to the treated arm, but many of the mosquitos flew past it. Carbon dioxide therefore appears to have a synergistic action with arm odours in the attraction of females of Aedes aegypti (L.). However, this conclusion does not exclude other behavioural effects of carbon dioxide demonstrated by other investigators. Eesponses to arms in this new type of olfactometer were nearly identical to those obtained in another type previously used in a large-scale study. The testing confirmed earlier reports that mosquitos do not fly far in the same direction as wind-current and that host location was not possible through positive anemotaxis in the absence of light. Mosquitos were not attracted to a source of infra-red radiation. The new direct method of comparing the attractiveness of different subjects demonstrated that mosquitos would leave the vicinity of one arm and migrate further upwind to another that was more attractive. Water and acetone rinses of human arms reduced attraction; acetone appeared to be a better solvent for the attractant substance than water.
Multimedia Retrieval via Deep Learning to Rank (2015)

Many existing learning-to-rank approaches are incapable of effectively modeling the intrinsic interaction relationships between the feature-level and ranking-level components of a ranking model. To address this problem, we propose a novel joint learning-to-rank approach called Deep Latent Structural SVM (DL-SSVM), which jointly learns deep neural networks and latent structural SVM (connected by a set of latent feature grouping variables) to effectively model the interaction relationships at two levels (i.e., feature-level and ranking-level). To make the joint learning problem easier to optimize, we present an effective auxiliary variable-based alternating optimization approach with respect to deep neural network learning and structural latent SVM learning. Experimental results on several challenging datasets have demonstrated the effectiveness of the proposed learning to rank approach in real-world information retrieval.
ChemInform Abstract: High Field Electron Spin Resonance (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Use of the Langmuir method for kinetic studies of decomposition reactions: calcite (CaCO3) (1974)

The Langmuir method for measurement of vapour pressures has been tested for use in studies of decomposition reactions. The isothermal weight loss in vacuum from cleavage (10text-decoration:overline11) planes of calcite (CaCO3) single crystals was measured continuously at temperatures from 934 to 1013 K. The rate was constant until approximately 80% of a 1 mm slice had decomposed. The apparent activation enthalpy was 205 kJ (49 kcal) mol–1. Micrographic examination showed an approximately 30 µm thick layer, probably a metastable form of calcium oxide, separating the calcite from the growing layer of oriented stable calcium oxide. The 30 µm layer yielded a single X-ray diffraction peak which was displaced slightly from the strongest (220) peak of the oriented normal calcium oxide. Lower apparent activation enthalpies measured in previous studies of calcite decomposition in inert atmospheres are suggested to result either from partial diffusion control of the process or from catalysis of the direct formation of normal calcium oxide by carbon dioxide or a component of the system atmosphere. The ratio of the measured decomposition rate in vacuum to the maximum rate, which can be calculated from the Hertz–Knudsen–Langmuir equation, is suggested to be a useful parameter in correlating and predicting decomposition reaction rates.
A luminescent europium(<scp>iii</scp>)–platinum(<scp>ii</scp>) heterometallic complex as a theranostic agent: a proof-of-concept study (2015)

A luminescent heterometallic multifunctional theranostic Eu-Pt2 complex [{cis-PtCl2(DMSO)}2Eu(L)(H2O)] has been synthesized, possessing two therapeutic Pt-centers as covalent DNA binders and one emissive Eu(3+)-center which is sensitized by platinum-based metal-to-ligand charge-transfer excited states.
Abrasive Jet Polishing of Micro Groove Using Compound SiC Abrasives with Compound Additives (2011)

This Study Examined the Performance of Abrasive Jet Polishing (ajp) on Skd61 Mold Surfaces Using Wax-coated Sic Abrasives Fabricated by Gas Atomization. Comparison of Surface Quality Achieved Reveals Significant Surface Roughness Reduction by Wax-coated Abrasives. the Wax Coating Not only Covers Most of the Sharp Ends of the Abrasive, Thus Making Smooth the Abrasive Surface; it Being Elastic Also Provides a Cushioning Buffer. these Two Features Contribute to Ameliorate the Direct Impact of Heavy Peening, Thus Preventing Surface Hardening, Superficial Embedment or Deep Scratches. Moreover, Compound Additives Including Water Wax and Water Were Added to the Wax-coated #3000 Sic Abrasives at a Mix Proportion of 500: 1000: 1500 (water Wax: Wax-coated Sic: Water) for Polishing Mold Surfaces of Different Forms. Results Show that the Compound Additives Provide Addition Cushioning Effect and Facilitate the Sliding and Grinding of Abrasives, Resulting in Fine Polishing and Good Surface Quality. the Reflection Property of Micro-groove Was much Enhanced by Ajp Using Wax-coated #3000 Sic Abrasives with the Compound Additives.
Applications of hidden Markov models to detecting multi-stage network attacks (2003)

This paper describes an approach using hidden Markov models (HMM) to detect complex Internet attacks. These attacks consist of several steps that may occur over an extended period of time. Within each step, specific actions may be interchangeable. A perpetrator may deliberately use a choice of actions within a step to mask the intrusion. In other cases, alternate action sequences may be random (due to noise) or because of lack of experience on the part of the perpetrator. For an intrusion detection system to be effective against complex Internet attacks, it must be capable of dealing with the ambiguities described above. We describe research results concerning the use of HMMs as a defense against complex Internet attacks. We describe why HMMs are particularly useful when there is an order to the actions constituting the attack (that is, for the case where one action must precede or follow another action in order to be effective). Because of this property, we show that HMMs are well suited to address the multi-step attack problem. In a direct comparison with two other classic machine learning techniques, decision trees and neural nets, we show that HMMs perform generally better than decision trees and substantially better than neural networks in detecting these complex intrusions.
Analysis of the use of Beta-blockers in congestive heart failure (2002)

Objective To study the usage situation of Beta blockers in CHF for the improvement of therapy. Methods To investigate the drug therapies of 986 CHF patients in cardiology department of Guangdong Provincial Hospital.Then the use of Beta Blockers in CHF was assessed according to guidelines of congestive heart failure and evidence based medicine. Results The used drugs from 1st to 3rd were: metoprolol,carvedilol,bisoprolol,and other used drugs were very few.Conclusion The results reflected the progress and new knowledge of the drug therapy in CHF,but there was a trend of abuse in some with discompensative with heart function.
A foveated image sensor in standard CMOS technology (2002)

We describe the design and implementation of a CMOS foveated image sensor for use in mobile robotic and machine vision applications. The sensor is biologically motivated and performs a spatial image transformation from Cartesian to log-polar coordinates. As opposed to traditional approaches, the sensor benefits from a high degree of integration, minimal power consumption and ease of manufacture due to the use of a standard 1.2 /spl mu/m ASIC CMOS process. The prototype imager operates at 28 frames/sec when interfaced to a PC.
Event-based applications and enabling technologies (2009)

Event processing has become the paradigm of choice in many monitoring and reactive applications. However, the understanding of events, their composition and level of abstraction, the style of processing and the quality of service requirements vary drastically across application domains. We introduce the basic notions of event processing to create a common understanding, present the enabling technologies that are used for the implementation of event-based systems, survey a wide range of applications identifying their main features, and discuss open research issues.
Simple effective mass model to include the effects of GAMMA - X mixing in multiquantum barriers (1994)

An extended effective mass model is developed to account for the possibility of mixing of the electron wave function from the Γ conduction-band state to the X conduction-band state. The strength of the mixing is determined by a mixing parameter Δ in association with the assumption of a finite interface thickness. For a simple quantum well, the model Δ compares favorably with more complicated empirical pseudopotential models, featuring complete descriptions of the band structure. A multiquantum barrier (MQB) has been designed. Using the single-band effective mass approximation model, for use in visible laser diode structures for enhanced electron confinement, it is clear that within the limitations of the model when mixing effects are accounted for, the degradation in performance is negligible. The MOB design compared with a single barrier of equivalent thickness shows a doubling of the electron reflection coefficient.