gebhart/patrepeval huggingface dataset:
Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa (1997)

Lipid peroxidation occurs in human sperm cells with damage to the cell plasma membrane, leading to loss of cytosolic components and hence to cell 'death'. The peroxidation may be induced at high rates in the presence of Fe2+ and ascorbate. It occurs at slower rates under physiological conditions as spontaneous lipid peroxidation, which has the following characteristics. The rate is constant over the time required for complete loss of motility in the cells of the sperm sample; one can thus use the time to complete loss of motility (TLM) as a ready measure of the rate. Loss of motility occurs at a characteristic extent of lipid peroxidation, assayed in terms of production of the peroxidative breakdown product, malonaldehyde (MA), that is independent of peroxidation rate. For human sperm, this extent corresponds to 0.1 nmol MA/10(8) cells. Human spermatozoa possess the anti-lipoperoxidative defence enzymes, superoxide dismutase (SOD) and glutathione peroxidase plus glutathione reductase (GPX/GRD). The SOD activity is highly variable between human sperm samples while the activities of GPX and GRD are rather more constant. The rates of production of superoxide anion, O2-, and hydrogen peroxide, H2O2, from human spermatozoa are variable, but their sum calculated in O2- equivalents as O2- + 2H2O2 is quite constant. The variability arises from the variability in SOD activity: all H2O2 produced is from O2- due to the action of SOD. The essential role of SOD as defence enzyme is inferred from the observation that TLM of a given sperm sample is directly proportional to the SOD activity of that sample. The essential role of GPX/GRD is inferred from the observation that inhibition of GPX, either with mercaptosuccinate or with complete oxidation of intracellular reduced glutathione, results in a 20-fold increase in peroxidation rate. The capacity of the GPX/GRD system appears to be limited by the glucose-6-phosphate dehydrogenase-catalysed rate of production of NADPH, the required reductive substrate for GRD. Human spermatozoa appear to have enough anti-lipoperoxidative defensive capacity for lifetimes long enough for fertilization but still short enough for ready removal from the female reproductive tract in good time. Too low a defence capacity could lead to male infertility.
Software Selection II (1994)

Gives information on software of interest to those working in the areas of food and nutrition including two shareware programs called Arcus Pro III and Kwickstat. Discusses the capabilities of each package and their suitability for use with different groups of people and in different types of research. Gives information on software costs, registration fees for shareware and the addresses from which further details can be obtained.
A simple chamber for observing microscopic specimens in both top and side views (1985)

A method is described which permits the observation of microscopic specimens in both top and side views, a rapid change between the two views being possible without disturbing the specimen. The system requires the introduction of simple optical components into a culture chamber, does not restrict the types of microscopy that may be used, and does not necessitate modification of the microscope itself. The technique is discussed in relation to the study of tissue cells in culture, but may find applications in other areas.
Host specificity of the rust Phragmidium violaceurn, a potential biological control agent of European blackberry (1986)

SUMMARY The host specificity of the rust fungus Phragmidium violaceum , a potential biological control agent of European blackberry ( Rubus fruticosus ) was studied by inoculating a mixture of 15 isolates of the rust on 108 plants of importance to the Australasian region. A scale of infection types was developed based on the results of microscopic and macroscopic observations of the reaction of host and non‐host plants to the rust. The results showed that P. violaceum has a limited host range in the genus Rubus . The rust was able to reproduce on 17 taxa of Rubus previously unrecorded as hosts, including Australasian species of Rubus subgenera Dalibarda and Lampobatus . All other taxa attacked were species of Rubus subgenus Eubatus and the majority were hybrid cultivars containing European blackberry species.
Kinetic modeling of in vivo—nuclear magnetic resonance spectroscopy data: 5–Fluorouracil in liver and liver tumors (1991)

Kinetic modeling has been applied to the time course of the nuclear magnetic resonance signal intensities of 5-fluorouracil and the sum of its catabolites, alpha-fluoro-beta-ureido propanoic acid and alpha-fluoro-beta-alanine, as monitored in liver tumors of seven patients with cancer after brief intraarterial infusion of 5-fluorouracil. Because these data represent only relative tissue concentrations, only ratios of clearance and volume parameters can be estimated (e.g., clearance/central volume of distribution or central volume of distribution/steady-state volume of distribution). On the other hand, parameters that do not refer to volumes, such as half-lives or maximal velocity of metabolic conversion of a nonlinear model, can be estimated in absolute terms. A nonlinear three-compartment model gave satisfactory fits with all of the individual data sets. Kinetics of 5-fluorouracil and catabolites were similar in five patients with metastases of colorectal adenocarcinomas but differed from those of two patients with cholangiocarcinoma and metastases of an anaplastic carcinoma of unknown origin, respectively.
An enhanced model for searching in semantic portals (2005)

Semantic Portal is the next generation of web portals that are powered by Semantic Web technologies for improved information sharing and exchange for a community of users. Current methods of searching in Semantic Portals are limited to keyword-based search using information retrieval (IR) techniques, ontology-based formal query and reasoning, or a simple combination of the two. In this paper, we propose an enhanced model that tightly integrates IR with formal query and reasoning to fully utilize both textual and semantic information for searching in Semantic Portals. The model extends the search capabilities of existing methods and can answer more complex search requests. The ideas in a fuzzy description logic (DL) IR model and a formal DL query method are employed and combined in our model. Based on the model, a semantic search service is implemented and evaluated. The evaluation shows very large improvements over existing methods.
Rock physics of organic shales (2011)

Several publications over the last 20 years have established that black organic shales are generally characterized by strong velocity anisotropy, low velocity in the bedding-normal direction, and relatively low density and porosity (e.g., Vernik and Nur, 1992; Vernik and Liu, 1997). These rock properties are of interest in seismic attribute studies, but even more so in geomechanical applications related to reservoir characterization and hydraulic fracture stimulation. Organic shales typically, but not necessarily, express strong vertical transverse isotropy (VTI), with axis of symmetry perpendicular to the bedding-parallel lamination and clay-particle-preferred orientation. High-resolution SEM imaging (Figure 1) immediately reveals all these textural features in addition to silt grains and the lenticular distribution of the solid organic matter (kerogen), which in turn is characterized by significant intraparticle porosity in mature shales. Any TI medium is described by the five independent elastic constants (C11, C33, C44, C66, and C13) and detailed multidirectional ultrasonic core measurements can provide the most accurate means for their adequate evaluation. Single-well sonic- and density-log data fall short of the full TI tensor description resulting in major ambiguities related to empirical correlations.
ChemInform Abstract: Tellurium Dioxide‐Catalyzed Selective Oxidation of Sulfides to Sulfoxides with Hydrogen Peroxide. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Attribute Oriented Induction with simple select SQL statement (2010)

Searching learning or rules in relational database for data mining purposes with characteristic or classification/discriminant rule in attribute oriented induction technique can be quicker, easy, and simple with simple SQL statement. With just only one simple SQL statement, characteristic and classification rule can be created simultaneously. Collaboration SQL statement with any other application software will increase the ability for creating t-weight as measurement the typicality of each record in the characteristic rule and d-weight as measurement the discriminating behavior of the learned classification/discriminant rule, particularly for further generalization in characteristic rule. Handling concept hierarchy into tables based on concept tree will influence for the successful simple SQL statement and by knowing the right standard knowledge to transform each of concept tree in concept hierarchy into one table as transforming concept hierarchy into table, the simple SQL statement can be run properly.
NEURAL ENCODING IN CAT GENICULATE GANGLION TONGUE UNITS (1974)

Problems associated with neural encoding in first order afferents are discussed. Neurophysiological data indicate that chemoresponsive cells of the cat geniculate ganglion can be subdivided into three different independent groups. Functional relationships between input and output variables must be established for each group. Spike train measures indicate that the neural outputs from single cells have several parameters of variability. Furthermore, the three different natural input stimulus dimensions have not been determined.
Toward immersive mobile virtual reality (2016)

Virtual reality head-mounted displays (VR HMDs) are attracting users with the promise of full sensory immersion in virtual environments. Creating the illusion of immersion on HMDs requires high framerate, low latency, and high visual quality --- a tall order for mobile device-based VR approaches. In this talk, I will discuss two systems we have built to overcome the inherent limitations of mobile VR. The first, Outatime, focuses on compute offload via app streaming, an emerging app execution model in which remote rendering servers stream interactive video to thin clients. While servers dwarf mobile devices in compute power, the key challenge is coping with network latency. I will discuss how we have employed speculative execution to overcome this challenge on high-quality VR games. The second system, Flashback, aggressively precomputes all possible images that a VR user might encounter well ahead of time. During run-time, Flashback indexes into the device's storage hierarchy to quickly lookup images that the user ought to be seeing. Flashback not only works for static scenes, but also for dynamic scenes with moving and animated objects. We observe substantial improvements in framerate, latency and energy consumption. In some cases, it even delivers better framerate and responsiveness than a tethered high-end computer.
Autoreactive T Cells Revealed in the Normal Repertoire: Escape from Negative Selection and Peripheral Tolerance (2002)

Self-reactive T cells are known to be eliminated by negative selection in the thymus or by the induction of tolerance in the periphery. However, developmental pathways that allow self-reactive T cells to inhabit the normal repertoire are not well-characterized. In this investigation, we made use of anti-small nuclear ribonucleoprotein particle (snRNP) Ig transgenic (Tg) mice (2-12 Tg) to demonstrate that autoreactive T cells can be detected and activated in both normal naive mice and autoimmune-prone MRL lpr/lpr mice. In contrast, autoreactive T cells of nonautoimmune Tg mice are tolerized by Tg B cells in the periphery. In adoptive transfer studies, autoreactive T cells from MRL lpr/lpr mice can stimulate autoantibody synthesis in nonautoimmune anti-snRNP Tg mice. Transferred CD4 T cells migrate to regions of the spleen proximal to the B cell follicles, suggesting that cognate B cell-T cell interactions are critical to the autoimmune response. Taken together, our studies suggest that anti-snRNP B cells are important APCs for T cell activation in autoimmune-prone mice. Additionally, we have demonstrated that anti-snRNP B cell anergy in nonautoimmune mice may be reversed by appropriate T cell help.
pH Effect on Protein G Orientation on Gold Surfaces and Characterization of Adsorption Thermodynamics (2012)

The pH effect on adsorbed antibody-binding protein (protein G) orientation on gold (Au) and its adsorption thermodynamic characteristics were investigated using quartz crystal microbalance (QCM) and X-ray photoelectron spectroscopy (XPS). The adsorbed protein G orientation was measured by binding response of two antibody-antigen systems: the model bovine serum albumin (BSA) and the foodborne pathogen E. coli O157:H7. Surface coverage was not significantly affected by pH, but its orientation was. The most properly oriented protein G for antibody binding was achieved at near-neutral pH. Adsorption was verified by XPS measurements using nitrogen (N) 1s, oxygen (O) 1s, and Au 4p peak heights. Adsorption energetics were determined by van't Hoff and Langmuir kinetic analyses of adsorption data obtained at 296, 303, and 308 K. Large characteristic entropy change of protein adsorption was observed (ΔS° = 0.52 ± 0.01 kcal/mol·K). The adsorption process was not classical physisorption but exhibited chemisorption characteristics based on significant enthalpy change (ΔH° = -25 ± 6 kcal/mol).
Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. (1993)

Tumor necrosis factor-alpha (TNF) has recently been shown to induce insulin resistance. We have examined the possible effect of TNF on the early events in insulin transmembrane signaling. Incubation of the insulin-sensitive rat hepatoma Fao cells with 5 nM TNF for 1 h led to a 65% decrease in insulin-induced tyrosine phosphorylation of both the insulin receptor beta-subunit and IRS-1, its major cytosolic substrate. TNF-induced impairment of tyrosine phosphorylation was maximal at 0.5 nM and was not accompanied by any reduction in insulin binding. Sixteen hours of TNF incubation led to further impairment in insulin-induced tyrosine phosphorylation of these proteins. Our findings suggest that TNF may exert its anti-insulin effect by interrupting the early insulin-stimulated tyrosine phosphorylation events, which are crucial to insulin transmembrane signaling.
Observations of the Vibration of the Basilar Membrane in Squirrel Monkeys using the Mössbauer Technique (1971)

The amplitude and the phase of vibration of the basilar membrane and the bony limbus of the cochlea were measured in living squirrel monkeys using the Mössbauer technique. In the middle ear, the vibration of the malleus (and occasionally the incus) was measured. The Mössbauer technique makes possible the measurement of very small velocities, e.g., 0.2 mm/sec. This sensitivity permits measurement of the motion of the malleus at sound-pressure levels (SPLs) of 90 to 110 dB and measurement of the motion of the basilar membrane at 70 to 120 dB SPL, depending on the frequency. The basilar membrane vibrates nonlinearly for frequencies which produce the largest deflections at the spot on the basilar membrane under observation. The ratio of the displacement of the basilar membrane to that of the malleus was observed to have the following characteristics: (1) As the frequency is increased from a low value, its amplitude increases at 6 dB/oct until just below the maximum ratio where the slope increases to about 24 dB/oct; (2) the maximum ratio was about 24 dB for the SPLs used; (3) for frequencies above that producing the maximum ratio, the drop-off rate was approximately 100 dB/oct; (4) the amplitude ratio did not drop off indefinitely but tended to level off; (5) the motion of the basilar membrane differs from the motion of the malleus by 90° at very low frequencies; (6) for frequencies below that producing the maximum ratio, the phase differences between the motion of the basilar membrane and that of the malleus is a linear function of frequency; (7) near the frequency corresponding to the maximum ratio, the phase difference decreases at a faster rate; and (8) the phase difference approaches a constant value (7π 8π or 9π) for high frequencies. Anatomical constraints allowed only a small portion of the basal turn to be studied (6.5–7.5 kHz produced maximum deflection of the basilar membrane in this region).
OptARQ: A SPARQL Optimization Approach based on Triple Pattern Selectivity Estimation (2007)

Abstract Query engines for ontological data based on graph models mostly execute user queries without considering any optimization. Especially for large ontologies, optimization techniques are required to ensure that query results are delivered within reasonable time. OptARQ is a first prototype for SPARQL query optimization based on the concept of triple pattern selectivity estimation. The evaluation we conduct demonstrates how triple pattern reordering according to their selectivity affects the query execution performance.
Novel Procedure for the Extraction and Concentration of Carotenoid-Containing Chromoplasts from Selected Plant Systems (2007)

Natural sources of carotenoids for nutraceutical use are desired by the food industry as a result of the increased production of convenience and other highly processed foods. As new physiological roles are discovered for some of the minor carotenoids that are found in only small amounts in present sources, the need for discovery of new sources will amplify. Thus, a method is needed that will effectively and gently concentrate carotenoids from potential new sources for subsequent identification and analysis. A procedure is presented by which carotenoid-containing tissue chromoplasts can be extracted and subsequently concentrated by precipitation, all in an aqueous milieu. The chromoplasts are extracted and solubilized with 0.3% sodium dodecyl sulfate (SDS) in water. The addition of a nominally equal volume of acetonitrile to the chromoplasts in SDS immediately precipitates the chromoplasts out of solution with generally >90% recovery. Carotenoids contained in the concentrated, still-intact chromoplasts can then be solubilized by organic solvent extraction for subsequent analysis. This methodology offers a means to effectively and gently concentrate carotenoids from fruit tissues where yields are often low (e.g., yellow watermelon).
Inverse multiplexing in short-range multi-transport wireless communications (2004)

This paper describes a mechanism for utilizing inverse multiplexing to significantly increase the bandwidth available to short-range wireless devices. Previous work with inverse multiplexing has focused on wired networks; its implementation with short-range wireless transports introduces heterogeneity in the links, which must be taken into account. A mathematical model for an inverse multiplexing system is derived for several scheduling algorithms. Both process limited and transport limited systems are examined. The validity of this model is shown by our implementation of an inverse multiplexing layer that uses IrDa and Bluetooth transports. Concepts related to inverse multiplexing such as usage models, negotiation, quality of service, and the simultaneous use of multiple Bluetooth transports are discussed.
Regulation of triglyceride metabolism by glucocorticoid receptor (2012)

Glucocorticoids are steroid hormones that play critical and complex roles in the regulation of triglyceride (TG) homeostasis. Depending on physiological states, glucocorticoids can modulate both TG synthesis and hydrolysis. More intriguingly, glucocorticoids can concurrently affect these two processes in adipocytes. The metabolic effects of glucocorticoids are conferred by intracellular glucocorticoid receptors (GR). GR is a transcription factor that, upon binding to glucocorticoids, regulates the transcriptional rate of specific genes. These GR primary target genes further initiate the physiological and pathological responses of glucocorticoids. In this article, we overview glucocorticoid-regulated genes, especially those potential GR primary target genes, involved in glucocorticoid-regulated TG metabolism. We also discuss transcriptional regulators that could act with GR to participate in these processes. This knowledge is not only important for the fundamental understanding of steroid hormone actions, but also are essential for future therapeutic interventions against metabolic diseases associated with aberrant glucocorticoid signaling, such as insulin resistance, dyslipidemia, central obesity and hepatic steatosis.
Networked Control System Design over a Wireless LAN (2006)

We analyze and implement a networked control system where the communication between the sensors, the controller, and the actuator takes place over a wireless LAN (802.11b) ad hoc system. The wireless LAN system introduces random delays and packet loss in the feedback loop. We present an extended version of the separation principle of Linear Quadratic Gaussian (LQG) control with both random delays and packet loss in the feedback loop. This paper is motivated by many of the implementation constraints encountered during the setup of an experimental NCS. We see from our experimental data that the optimal LQG controller that takes the delays and loss into account indeed performs better than traditional control methods.
Advances in 3G Mobile Enhanced Technologies for Wireless Communications (2002)

Part I Wideband CDMA for 3G - Wideband CDMA Enhanced Technologies. Capacity Enhancement Technologies in 3GPP Standard. Part II: EDGE for 3G - GSM/EDGE Radio Access Network (GERAN) - Evolution of GSM/EDGE Towards 3G Mobile services. Part III: CDMA2000 for 3G - Peak-to-Average Ratio (PAR) of CDMA. CDMA200 High Rate Packet Data Systems. Part IV: Wireless Internet - IP Mobility Framework for Supporting Wireless and Mobile Internet. Part V: Software Radio - Software Radio: A Prospective Technology for the 4G.
Heterophoria and fixation disparity: A review (2000)

Heterophoria does not provide a reliable clue for ordering prisms in an asthenopic patient. The same reservation applies to associated phoria, as determined by prism correction of fixation disparity. Subjective tests for fixation disparity, even those with a fusionable fixation target, do not correctly indicate the vergence position of the eyes under natural viewing conditions. Attempts to measure fixation disparity on the basis of stereo disparity, using the "Measuring and Correction Methods of H.-J. Haase", have failed.