gebhart/patrepeval huggingface dataset:
Dynamic conversion between XML-based languages for vector graphics (2006)

Vector graphics is increasingly gaining importance within the Word Wide Web community, because it allows users to create images that are easily manageable, modifiable and understandable. Two formats play a leading role among the languages for vector graphics: SVG and VML. Achieving a complete interoperability between these two languages means providing users a complete support for vector images across implementations, operating systems and media. In this paper we describe VectorConverter, a tool that allows easy, automatic and reasonably good conversion between two vector graphic formats, SVG and VML, and one raster format, GIF. This tool makes good translations between languages with very different functionalities and expressivity, by applying translation rules, approximation and heuristics. A high-level discussion about implementation details, open issues and future developments of VectorConverter is provided as well.
Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers (2019)

Our results suggest safety and tolerability of orally administered 5 μg, 10 μg, and 20 μg LSD every fourth day over a 21-day period and support further clinical development of LSD for the treatment and prevention of Alzheimer's disease (AD).
[The combination of oral lysine-acetylsalicylate and metoclopramide compared with oral sumatriptan in the treatment of migraine attacks. A randomized, double-blind, placebo-controlled clinical trial]. (1996)

A combination of lysine acetylsalicylate (equivalent to 900 mg aspirin) and 10 mg metoclopramide (LAS + MTC) was compared with oral sumatriptan (100 mg) and placebo in 421 patients with migraine in a randomized, double-blind, clinical trial. LAS + MTC was as effective as sumatriptan with a decrease in headache from severe or moderate to mild or none in 57% and 53%, respectively, for the first migraine attack treated, the primary efficacy parameter. Both treatments were better than placebo (success rate 24%, p < 0.001). LAS + MTC was better tolerated than sumatriptan (adverse events in 18% and 28%, respectively, p < 0.05).
HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells (2012)

Abstract Background Lens epithelium–derived growth factor (LEDGF/p75) is a cellular co-factor of HIV-1 integrase (IN) that tethers the viral pre-integration complex to the host cell chromatin and determines the genome wide integration site distribution pattern of HIV-1. Recently, we demonstrated that HIV-1 replication was reduced in LEDGF/p75 knockout (KO) cells. LEDGF/p75 KO significantly altered the integration site preference of HIV-1, but the pattern remained distinct from a computationally generated matched random control set (MRC), suggesting the presence of an alternative tethering factor. We previously identified Hepatoma-derived growth factor related protein 2 (HRP-2) as a factor mediating LEDGF/p75-independent HIV-1 replication. However, the role of HRP-2 in HIV-1 integration site selection was not addressed. Findings We studied the HIV-1 integration site distribution in the presence and absence of LEDGF/p75 and/or HRP-2, and in LEDGF/p75-depleted cells that overexpress HRP-2. We show that HRP-2 functions as a co-factor of HIV-1 IN in LEDGF/p75-depleted cells. Endogenous HRP-2 only weakly supported HIV-1 replication in LEDGF/p75 depleted cells. However, HRP-2 overexpression rescued HIV-1 replication and restored integration in RefSeq genes to wild-type levels. Additional HRP-2 KD in LEDGF/p75-depleted cells reduces integration frequency in transcription units and shifts the integration distribution towards random. Conclusions We demonstrate that HRP-2 overexpression can compensate for the absence of LEDGF/p75 and indicate that the residual bias in integration targeting observed in the absence of LEDGF/p75 can be ascribed to HRP-2. Knockdown of HRP-2 upon LEDGF/p75 depletion results in a more random HIV-1 integration pattern. These data therefore reinforce the understanding that LEDGF/p75 is the dominant HIV-1 IN co-factor.
NOTE ON THE STEADY FLOW OF A FLUID PAST A THIN AEROFOIL (1955)

Journal Article NOTE ON THE STEADY FLOW OF A FLUID PAST A THIN AEROFOIL Get access D. S. JONES D. S. JONES Manchester Search for other works by this author on: Oxford Academic Google Scholar The Quarterly Journal of Mathematics, Volume 6, Issue 1, 1955, Pages 4–8, https://doi.org/10.1093/qmath/6.1.4 Published: 01 January 1955 Article history Received: 20 March 1954 Published: 01 January 1955
Study of local properties of fibre Bragg gratings by the method of optical space-domain reflectometry (2003)

The method of optical space-domain reflectometry for measuring local spatial characteristics of fibre Bragg gratings (FBGs) is described in detail. It is demonstrated experimentally that, by using IR and UV radiation sources, this method provides good sensitivity (~10-4) of measuring the modulation amplitude of the induced refractive index in the core of an optical fibre and a high spatial resolution (~100 μm and better). The factors affecting the accuracy of measurements as well as technical and methodological limitations of the method are considered. A comparative analysis of modern methods for studying the spatial properties of FBGs is performed and applications of these methods are considered.
SU‐FF‐I‐28: A Novel Simulated Method of Quantifying Susceptibilities in Objects: The First Step Toward Quantitative Diagnosis in MRI (2005)

Quantifying tissue susceptibilities in‐vivo is important because certain tissue susceptibilities may reflect health conditions of an individual. Many researchers have accurately measured susceptibilities of different materials using the least‐square‐fit method when the object sizes occupy at least 50 pixels on MRI. In this abstract we have developed a new approach to measure susceptibilities of small objects from MRI. We first simulated a disk with a radius of 16 pixels on 4096×4096 magnitude and phase images. The disk was a cross section of an infinite tube, perpendicular to the main magnetic field in MRI. The magnitude inside the disk was zero but unity outside the disk. The echo time and the field strength were chosen as 5ms and 1.5T. The phase was then simulated according to the well‐known physics laws in magnetostatics, with a −9ppm susceptibility difference inside and outside the tube. Through a low‐pass k‐space filter, the sizes of images were then converted to 256×256 such that the radius of the disk became roughly 1 pixel. The 256×256 magnitude and phase images would be almost identical to images acquired from a 1.5T MR system, with an air tube of radius 1mm perpendicular to the magnetic field and surrounded by water. Our images were simulated with different tube radii as well as with and without Gaussian noises. Two circles around the disk were drawn on images. The centers of these two circles were coincided with the center of the disk. With each circle, the complex signal was summed. We were able to solve the susceptibility from an inverse approach, based on the known disk sizes, the comparisons of the obtained complex sums, and a theoretical model. Without the presence of noise, the solved susceptibilities were within 1% accuracy compared to −9ppm. With the presence of noise, the results are more complicated.
Allergen-Specific CD4+ T Cells in Human Asthma (2016)

In allergic asthma, aeroallergen exposure of sensitized individuals mobilizes robust innate and adaptive airway immune responses, stimulating eosinophilic airway inflammation and the activation and infiltration of allergen-specific CD4(+) T cells into the airways. Allergen-specific CD4(+) T cells are thought to be central players in the asthmatic response as they specifically recognize the allergen and initiate and orchestrate the asthmatic inflammatory response. In this article, we briefly review the role of allergen-specific CD4(+) T cells in the pathogenesis of human allergic airway inflammation in allergic individuals, discuss the use of allergen-major histocompatibility complex class II tetramers to characterize allergen-specific CD4(+) T cells, and highlight current gaps in knowledge and directions for future research pertaining to the role of allergen-specific CD4(+) T cells in human asthma.
Refractive index of some oxide and fluoride coating materials (1979)

Spectroreflectometry was used to measure the refractive index of the following optical coating materials: Ta(2)O(5), HfO(2), Y(2)0(3), La(2)O(3), ZrO(2), CeO(2), CeF(3), LaF(3), NdF(3), MgF(2) in the 250-2000-nm spectral range.
Glucan stimulates human dermal fibroblast collagen biosynthesis through a nuclear factor‐1 dependent mechanism (2002)

Glucan, an immunomodulator, has been reported to increase collagen deposition and tensile strength in experimental models of wound repair. Previous data suggest that glucan modulates wound healing via an indirect mechanism in which macrophages are stimulated to release growth factors and cytokines. However, recent data have shown the presence of glucan receptors on normal human dermal fibroblasts, suggesting that glucans may be able to directly stimulate fibroblast collagen biosynthesis. To test this hypothesis, we examined the effect of glucan on collagen biosynthesis in normal human dermal fibroblasts. We assessed nuclear factor-1 (NF-1) activation, procollagen mRNA expression, collagen biosynthesis, and whether there was a causal link between glucan treatment, NF-1 activation, and collagen expression. Glucan (1 microg/ml) increased NF-1 binding activity by 46% (8 hours), 64% (24 hours), 215% (36 hours), and 119% (48 hours) in cultured normal human dermal fibroblasts. Alpha 1(I) and alpha1 (III) procollagen mRNA were increased in glucan-treated normal human dermal fibroblasts when compared with the untreated fibroblasts. Collagen synthesis was increased at 24 hours and 48 hours following glucan treatment of normal human dermal fibroblasts. Down-regulation of NF-1 by pentifylline inhibited glucan-induced procollagen mRNA expression. These data indicate that glucan can directly stimulate human fibroblast collagen biosynthesis through an NF-1-dependent mechanism.
Broad 4-Hydroxyphenylpyruvate Dioxygenase Inhibitor Herbicide Tolerance in Soybean with an Optimized Enzyme and Expression Cassette  (2014)

With an optimized expression cassette consisting of the soybean (Glycine max) native promoter modified for enhanced expression driving a chimeric gene coding for the soybean native amino-terminal 86 amino acids fused to an insensitive shuffled variant of maize (Zea mays) 4-hydroxyphenylpyruvate dioxygenase (HPPD), we achieved field tolerance in transgenic soybean plants to the HPPD-inhibiting herbicides mesotrione, isoxaflutole, and tembotrione. Directed evolution of maize HPPD was accomplished by progressively incorporating amino acids from naturally occurring diversity and novel substitutions identified by saturation mutagenesis, combined at random through shuffling. Localization of heterologously expressed HPPD mimicked that of the native enzyme, which was shown to be dually targeted to chloroplasts and the cytosol. Analysis of the native soybean HPPD gene revealed two transcription start sites, leading to transcripts encoding two HPPD polypeptides. The N-terminal region of the longer encoded peptide directs proteins to the chloroplast, while the short form remains in the cytosol. In contrast, maize HPPD was found almost exclusively in chloroplasts. Evolved HPPD enzymes showed insensitivity to five inhibitor herbicides. In 2013 field trials, transgenic soybean events made with optimized promoter and HPPD variant expression cassettes were tested with three herbicides and showed tolerance to four times the labeled rates of mesotrione and isoxaflutole and two times the labeled rates of tembotrione.
Secret Sharing and Non-Shannon Information Inequalities (2011)

The known secret-sharing schemes for most access structures are not efficient; even for a one-bit secret the length of the shares in the schemes is 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">O(n)</sup> , where <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> is the number of participants in the access structure. It is a long standing open problem to improve these schemes or prove that they cannot be improved. The best known lower bound is by Csirmaz, who proved that there exist access structures with <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> participants such that the size of the share of at least one party is <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> /log <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> times the secret size. Csirmaz's proof uses Shannon information inequalities, which were the only information inequalities known when Csirmaz published his result. On the negative side, Csirmaz proved that by only using Shannon information inequalities one cannot prove a lower bound of ω(n) on the share size. In the last decade, a sequence of non-Shannon information inequalities were discovered. In fact, it was proved that there are infinity many independent information inequalities even in four variables. This raises the hope that these inequalities can help in improving the lower bounds beyond <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> . However, we show that any information inequality with four or five variables cannot prove a lower bound of ω( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> ) on the share size. In addition, we show that the same negative result holds for all information inequalities with more than five variables that are known to date.
The Anderson Quin Cycle (1993)

The objective of this study was to make a more refined evaluation of the Anderson Quin Cycle based on most recent information on the performance of various elements that will be used in the Anderson Quin Cycle. My original estimate of the work plan for evaluating and optimizing the Anderson Quin Cycle called for 7000 man hours of work. Since this grant was limited to 2150 man hours, we could not expect to achieve all the objectives within the allotted period of work. However, the most relevant program objectives have been completed as reported here. The analysis generally confirms the results originally estimated in my paper on the subject. (Ref. 2) Further optimizations should show even higher efficiencies. The Anderson Quin Cycle (US Patent applied for) basically consists of 5 elements in the power cycle: A refrigeration system to cool and clean the inlet air before it enters the compressor that supplies air for the gas turbine; a gas turbine consisting of a compressor, combustor, and turbine; a steam boiler and steam turbine system using the heat from the exhaust gas out of the gas turbine; a vapor turbine cycle, which utilizes the condensed heat from the exhaust of the steam turbine and the exhaust gas heat leaving the steam boiler to operate a vapor turbine cycle which utilizes another fluid than water, in this case isobutane; and the fifth element consists of a gas cooler and heat pump system, which removes the heat from the exhaust gas to lower its temperature essentially to atmospheric temperature, and at the same time permits treatment of the exhaust gas to remove acid components such as sulfur dioxide and nitrogen oxides. Current industry accepted component characteristics were incorporated in the performance analysis of the overall cycle, ensuring accurate and meaningful operating predictions. The characteristics and performance of each of the elements are described. The thermal efficiency of the optimized calculated Anderson Quin Cycle is 62 percent.
Enhancing effect of glyceryl-1-monooctanoate on the rectal absorption of Gentamicin from hollow-type suppositories in rabbits. (1989)

A hollow-type suppository containing gentamicin (GM) in its cavity was prepared using Witepsol H-15 (H-15) mixed with glyceryl-1-monooctanoate (MO) or MO alone in the body of the suppository (type I) and a suppository (type II) containing GM and MO in the cavity was constructed using H-15 in the body of the suppository. Without MO, GM (60 mg) was not absorbed (plasma GM levels less than 1 microgram/ml). However, the absorption of GM from the rectum of rabbits was enhanced by coadministered MO in types I and II. Even when the amount of GM was decreased to 6 mg (1/10), GM was observed in the plasma (Cmax, 3.5 +/- 0.3 micrograms/ml) after administration of the suppository made from MO mixed with H-15. The enhancing effect of MO on the rectal absorption of GM could not be further increased by incorporating an amount of MO larger than approximately 300 mg into the suppository. This study demonstrates that MO can be used in the two types of hollow suppositories as an effective enhancing agent of rectal absorption of poorly absorbed drugs such as GM.
ARTHROGRAPHY OF THE KNEE BY DOUBLE CONTRAST METHOD (1966)

ARTHROGRAPHY OF THE KNEE BY DOUBLE CONTRAST METHODROBERT H. FREIBERGER, M.D., PAUL J. KILLORAN, M.D. and GONZALO CARDONA, M.D.Audio Available | Share
Emerging radio-over-fiber technologies and networks: challenges and issues (2008)

Technologies for the transport of radio over optical fiber links have been developing rapidly in recent years and bandwidth demands have spurred researchers to look into higher frequencies and smaller cell sizes. Although many of the underlying techniques are developed, significant challenges still remain before these technologies can be integrated in fully functioning networks. This talk will review the recent developments in Radio-Over-Technologies, highlight the challenges that remain and outline the work being undertaken within the EU Network of Excellence BONE to meet these challenges.
Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): (2000)

Contains fulltext : 185889.pdf (Publisher’s version ) (Open Access)
Reactions of the hydroperoxyl radical (HO2) with nitrogen dioxide and tetranitromethane in aqueous solution (1975)

HO2 produced in a flow system by the electron beam irradiation of aerated formic acid solutions reacts with tetranitromethane (TNM) in acid solution in two stages. Rapid formation of nitroform by reaction (1) is followed by a delayed reaction with 0.5 s < t½ < 10 min. The delayed reaction forms nearly half the total nitroform at low [TNM] and pH; it is suppressed by KCNS and is believed to be due to reduction of TNM by peroxynitric acid (HO2NO2) formed in the mechanism: HO2⇌ O–2+ H+, C(NO2)4+–2→ C(NO2)–3+ O2+ NO2, k1= 2 × 109 dm3 mol–1 s–1(1), HO2+NO2→ HO2NO2k10= 4 × 109 dm3 mol–1 s–1(10), 2NO2→ N2O4, k13= 1010 dm3 mol–1 s–1(13), N2O4+ H2O → HNO2+ HNO3. Quantitative evidence for this mechanism is presented.
A Suggestion to the Construction of A Chemical Information Network Based on the NIH/EPA Chemical Information System (1984)

年ごろ，この産物の作り子が すべての組織をコンビュータ化した結果，それま でよりもコストの上がり方が一段と激しくなって
HYDROXYL CONTENT IN SILICA GEL “AEROSIL” (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHYDROXYL CONTENT IN SILICA GEL "AEROSIL"J. J. Fripiat and J. UytterhoevenCite this: J. Phys. Chem. 1962, 66, 5, 800–805Publication Date (Print):May 1, 1962Publication History Published online1 May 2002Published inissue 1 May 1962https://pubs.acs.org/doi/10.1021/j100811a007https://doi.org/10.1021/j100811a007research-articleACS PublicationsRequest reuse permissionsArticle Views1037Altmetric-Citations189LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Materials processing with YAG-lasers integrated in a turning center (1992)

The availability of high power YAG-lasers (cw, pulsed, Q-switched) with mean powers up to 2000 W guided by a thin, flexible glas fibre now facilitates the integration of lasers in machining centers using the laser beam as an additional tool. Hence, technologies like laser cutting, joining, hardening, drilling, laser-caving, structuring of surfaces and laser-marking can be applied additionally directly inside the machining centers in one setting, avoiding additional flow of the workpieces. Furthermore, materials with restricted machinability - especially hard materials like ceramics, hard metals, carbides or sintered alloys - can be shaped by laser-caving or laser assisted machining. Thus, the flexibility of machining centers of various types can be increased substantially. The design of a turning center with an integrated laser focussing optic and beam guiding via glass fibre will be presented. The laser focussing optic is designed to fit in the tool change system and the working space of the lathe and can be used alternatively with the cutting tools for turning and milling enabling a complete machining including laser processes. Laser-caving is one example demonstrating the facilities. Fundamental studies on laser-caving ceramics and tool-steels have been performed. An example on three-dimensional shaping with laser-caving - a thread bolt Tr 20×4 in the high-duty ceramic silicon-nitride machined in the lathe - now show the possibilities of this new technique supported by numerical simulation of the ablation process. To reach and ensure a high accurracy of the ablated geometries in laser-caving a closed loop control of the ablated depth is needed. Assisted by an optical sensor for measuring the ablated depth, control concepts and the design of a focussing optic as well as first steps in an automatic online-control of the process with this device will be presented. Outlooking, the potential of a complete machining combined with laser processes will be discussed describing in detail chip-breaking realized in the lathe itself. The results in drilling, welding, hardening (and cutting) with high power YAG lasers and fibre beam known from other workers show the possibilties and and a suitable selection of workpieces for the machining in a lathe.
Effects of B and Ge codoping on minority carrier lifetime in Ga-doped Czochralski-silicon (2009)

We investigated the effects of B/Ge codoping on the minority carrier lifetime in gallium (Ga)-doped Czochralski-silicon (CZ-Si) crystals. Minority carrier lifetime decreased from 28 to 0.1 μs when the B concentration was increased from 1×1015 to 1×1017 cm−3 in Ga/B codoped CZ-Si crystals. The minority carrier lifetime increased from 30 to 76 μs with increasing Ge concentration from 1×1017 to 2×1020 cm−3 in Ga/Ge codoped CZ-Si crystals. Light-induced degradation experiments showed that Ga/B codoped CZ-Si degraded rapidly, while Ga/Ge codoped CZ-Si showed no degradation. Moreover, the flow pattern defect density related to grown-in microdefects in as-grown Ga/Ge codoped CZ-Si decreased with increasing Ge concentration. The experimental results are explained using a defect reaction model based on the formation of Ge-vacancy-oxygen dimer complexes in the CZ-Si crystal during postgrowth cooling.