gebhart/patrepeval huggingface dataset:
Detection of herpes simplex virus DNA in human spermatozoa by in situ hybridization technique. (1998)

The role of herpes simplex virus (HSV) in male infertility has been investigated using the localizing ability of in situ hybridization technique. Sperm samples obtained from 80 men attending a maternity center because of fertility problems were classified by spermogram and analyzed for the presence of HSV-1 and HSV-2 DNA using digoxigenin-labelled DNA probes. HSV DNA was detected in the nuclei of spermatozoa in 37 semen samples (46%), HSV-1 specifically in 21 cases (26%) and HSV-2 in 16 cases (20%). HSV infection was almost three times more common in semens with a sperm count lower than 20 million/ml in relation to semens with a sperm count higher than 20 million/ml (70% versus 25.5%, P = 0.0001). The mean sperm count and motility for HSV positive semens were 23.5% and 36% respectively, whereas those of HSV negative semens were 53.2% and 47% respectively (P(count) = 0.0005 and P(motility) = 0.01). The number of HSV positive sperm cells ranged from 2 cells per specimen to 60% of the sperm cells. The mean number of HSV-2 labelled sperm cells per sample was 3.7% and that of HSV-1 1.5%. The percentage of hybridization positive sperm cells was also inversely correlated with sperm count and motility. Acyclovir therapy of eight males with HSV positive semens resulted in three successful pregnancies. In conclusion, HSV seems to play an important role in male infertility and the detection of this virus in the semen will not only allow substantial therapeutic interventions for the restoration of fertility but it will also contribute to the control of the transmission of HSV infection.
Bandwidth control of long-period grating-based mode converters in few-mode fibers (2002)

Control of the group-velocity differences between two distinct modes in a few-mode fiber can be used to define the spectral characteristics of long-period gratings written in them. Using this effect, we report the demonstration of strong mode conversion (>99%) with long-period fiber gratings over what is believed to be a record bandwidth of 63 nm. These novel spectra are obtained from gratings written in specially designed few-mode fibers in which the grating phase-matching condition is satisfied over a large spectral range. We show that the bandwidths of such mode converters can be tailored by suitably altering the design of the few-mode fibers. The polarization-dependent coupling for the mode converters varies by less than 0.004% over the entire spectrum.
Effects of a Ruminal Methane Inhibitor on Growth and Energy Metabolism in the Ovine (1974)

Twenty-four crossbred lambs weighing 14.1 to 27.2 kg were divided into three groups of eight each and balanced for sex and weight. The groups were then assigned to one of the three treatments 0, 1.5 and 3.0 mg bromochloromethane (BCM)/kgW/day for the 105-day growth trial. The lambs were fed a commercial pelleted lamb growing ration ad libitum to which the BCM premix was added at each feeding. No significant differences among treatments were found for average daily DM intake, average daily gain, or feed efficiency. Sixteen respiration calorimetry trials were conducted using four mature Suffolk wether sheep weighing 64.4 to 80.7 kg and randomly assigned to three treatment levels of 1.5, 3.0 and 4.5 mg BCM/kgW/day following a control trial at 0 mg BCM/kgW/day. The wethers were fed the same ration as the growing lambs but at maintenance level. BCM feeding resulted in about an 85% inhibition of methane production, which was a highly significant (P<.01) decrease compared to control values.
Development of porous 316L stainless steel with controllable microcellular features using selective laser melting (2008)

The regularly shaped parallel pore gas armed (GASAR) stainless steel porous material with a homogeneous size distribution of unusually micrometer scaled pores (2 μm in average) was successfully prepared using selective laser melting process, by adding 0·10 wt-% gas generating materials in the form of H 3 BO 3 and KBF 4 . The adjustment of pore morphology, pore direction, and porosity was realised by changing material combinations (such as the content of additive materials) and processing conditions (such as the scan speed of laser beam).
Cloud effective particle size and water content profile retrievals using combined lidar and radar observations: 2. Comparison with IR radiometer and in situ measurements of ice clouds (2001)

A new combined iidar/radar inversion procedure has been developed for cloud effective radius and water content retrievals. The algorithm treats the lidar extinction, derived effective particle size, and multiple‐scattering effects together in a consistent fashion. This procedure has been applied to data taken during the Netherlands Cloud and Radiation (CLARA) campaign and the Cloud Lidar and Radar Experiment (CLARE'98) multisensor cloud measurement campaign. The results of the algorithm compare well with simultaneous IR radiometer cloud measurements as well as with measurements made by using aircraft‐mounted two‐dimensional probe particle‐sizing instruments.
Identifying Multiple Userids of the Same Author (2013)

This paper studies the problem of identifying users who use multiple userids to post in social media.Since multiple userids may belong to the same author, it is hard to directly apply supervised learning to solve the problem.This paper proposes a new method, which still uses supervised learning but does not require training documents from the involved userids.Instead, it uses documents from other userids for classifier building.The classifier can be applied to documents of the involved userids.This is possible because we transform the document space to a similarity space and learning is performed in this new space.Our evaluation is done in the online review domain.The experimental results using a large number of userids and their reviews show that the proposed method is highly effective.
A new localization method for mobile robot by data fusion of vision sensor data and motion sensor data (2012)

This paper presents a new localization method by the data fusion of vision sensor and motion sensor measurements, which can be used for mobile robots. The developed system estimates the orientation, position and velocity of a mobile robot. This is achieved by using data from a camera, robot wheel encoders, an accelerometer, and a gyroscope. The developed system is a multi-rate sampled data system. For the accurate estimation of robot position and velocity, the developed method detects the slip of robot wheels, by comparing the data from the encoders and the accelerometer. The developed method estimates the robot orientation and position by using an extended Kalman filter. The experiments are performed to verify the localization performance of the developed method in several motion scenarios, including a normal operation mode, a wheel slip mode, and a kidnap mode.
Study of back reflectors for amorphous silicon alloy solar cell application (1991)

The role of back reflectors in enhancing the absorption of weakly absorbing, long-wavelength light has been investigated as applied to amorphous silicon alloy solar cells. The reflectance and scattering properties of various types of back reflectors have been studied. The performance of p-i-n amorphous silicon alloy solar cells deposited on different back reflectors has been analyzed. The studies elucidate the role of back reflectors in improving the short-circuit current density and thereby the efficiency of the cell.
The use of pulse synthesis for optimization of photoacoustic measurements (2009)

In this paper the use of pulse shaping in photoacoustic (PA) measurements is presented. The benefits of this approach are demonstrated by utilizing it for optimization of either the responsivity or the sensitivity of PA measurements. The optimization is based on the observation that the temporal properties of the PA effect can be represented as a linear system which can be fully characterized by its impulse response. Accordingly, the response of the PA system to an input optical pulse, whose instantaneous power is arbitrarily shaped, can be analytically predicted via a convolution between the pulse envelope and the PA impulse response. Additionally, the same formalism can be used to show that the response of the PA system to a pulse whose instantaneous power is a reversed version of the impulse response, i.e. a matched pulse, would exhibit optimal peak amplitude when compared with all other pulses with the same energy. Pulses can also be designed to optimize the sensitivity of the measurement to a variation in a specific system parameter. The use of the matched pulses can improve SNR and enable a reduction in the total optical energy required for obtaining a detectable signal. This may be important for applications where the optical power is restricted or for dynamical measurements where long integration times are prohibited. To implement this new approach, a novel PA optical setup which enabled synthesis of excitation waveforms with arbitrary temporal envelopes was constructed. The setup was based on a tunable laser source, operating in the near-IR range, and an external electro-optic modulator. Using this setup, our approach for system characterization and response prediction was tested and the superiority of the matched pulses over other common types of pulses of equal energy was demonstrated.
Clinical Application of iNKT Cell-mediated Anti-tumor Activity Against Lung Cancer and Head and Neck Cancer (2018)

Invariant natural killer T (iNKT) cells produce copious amounts of cytokines in response to T-cell receptor (TCR) stimulation by recognizing antigens such as α-galactosylceramide (α-GalCer) presented on CD1d; thus, orchestrating other immune cells to fight against pathogen infection and tumors. Because of their ability to induce strong anti-tumor responses and the convenience of their invariant TCR activated by a synthetic ligand, α-GalCer, iNKT cells have been intensively studied for application in immunotherapeutic approaches to treat cancer patients in the clinic. Here, we summarize the clinical trials of iNKT cell based immunotherapy for non-small cell lung cancer, and head and neck cancer. Although solid tumors are thought to be refractory to immunotherapeutic approaches, our clinical trials showed that the intravenous injection of α-GalCer-pulsed antigen presenting cells (APCs) activated endogenous iNKT cells and iNKT cell dependent responses. Moreover, an increase in the number of IFN-γ producing cells in PBMCs was associated with prolonged survival. The marked infiltration of iNKT cells and the accumulation of conventional T cells in the tumor microenvironment were also observed after the administration of α-GalCer-pulsed APCs and/or <i>ex vivo</i> activated iNKT cells. In cases of advanced head and neck squamous cell carcinoma, the increased accumulation of iNKT cells in the tumor microenvironment was correlated with objective clinical responses. We will also discuss potential combination therapies of iNKT cell based immunotherapy to achieve enhanced anti-tumor activity and provide better treatment options for these patients.
A Photoelectrochromic Memory and Display Device Based on Conducting Polymers (1984)

We report a new photoelectrochromic system for information storage and display applications. This system is based on the electrochromic properties of thin films of electrochemically generated conducting polymers. These materials can be switched between two states of optical absorption: a highly absorbing, almost‐black film in the oxidized state, and an almost‐transparent film in the reduced state. On an n‐type semiconductor surface, oxidation of the conducting polymer requires illumination of the semiconductor surface. A thin film of conducting polymer photoelectrochemically generated onto a semiconductor surface can thus be reversibly bleached by a cathodic potential and blackened by anodic potential simultaneous with a light pulse. Such a device works as an optical memory which can be erased electrically and written optically with a scanning modulated light beam. We report on initial studies of the n‐Si/poly(N‐methylpyrrole) system in acetonitrile electrolyte.
Compressionless routing: a framework for adaptive and fault-tolerant routing (1997)

Compressionless routing (CR) is an adaptive routing framework which provides a unified framework for efficient deadlock free adaptive routing and fault tolerance. CR exploits the tight coupling between wormhole routers for flow control to detect and recover from potential deadlock situations. Fault tolerant compressionless routing (FCR) extends CR to support end to end fault tolerant delivery. Detailed routing algorithms, implementation complexity, and performance simulation results for CR and FCR are presented. These results show that the hardware for CR and FCR networks is modest. Further, CR and FCR networks can achieve superior performance to alternatives such as dimension order routing. Compressionless routing has several key advantages: deadlock free adaptive routing in toroidal networks with no virtual channels, simple router designs, order preserving message transmission, applicability to a wide variety of network topologies, and elimination of the need for buffer allocation messages. Fault tolerant compressionless routing has several additional advantages: data integrity in the presence of transient faults (nonstop fault tolerance), permanent fault tolerance, and elimination of the need for software buffering and retry for reliability. The advantages of CR and FCR not only simplify hardware support for adaptive routing and fault tolerance, they also can simplify software communication layers.
The Effects of Globalization on Working Conditions in Developing Countries : An Analysis Framework and Country Study Results (2008)

Globalization defined as falling\n barriers to, and the increase in, trade, migration, and\n investment across borders directly affects workers in both\n developed and developing countries. While most global trade\n and investment is between the developed countries,\n globalization has increased dramatically in a number of\n developing countries. Understanding the effects of\n globalization is critical for governments concerned about\n employment, working conditions, and, ultimately, poverty\n reduction. Broadly defined, working conditions include wages\n and other key job characteristics including (but not\n necessarily limited to) health and safety, hours, security,\n benefits, and representation. These conditions have direct\n and indirect effects on the risk of falling or staying in\n poverty. This note outlines an approach for a systematic\n cross-country comparison of the relationship between\n globalization and working conditions. In addition, the\n results from applying this approach to five countries\n (Cambodia, El Salvador, Honduras, Indonesia, and Madagascar)\n are presented. The country study results described in this\n note support the hypothesis that globalization has\n contributed to a shift of workers from sectors with low wage\n and poor non-wage working conditions (i.e., agriculture) to\n sectors with relatively higher wages and better non-wage\n working conditions.
Src-Dependent Tyrosine Phosphorylation at the Tips of Growth Cone Filopodia Promotes Extension (2005)

Extracellular cues guide axon outgrowth by activating intracellular signaling cascades that control the growth cone cytoskeleton. However, the spatial and temporal coordination of signaling intermediates remains essentially unknown. Live imaging of tyrosine phosphorylation in growth cones revealed dynamic phospho-tyrosine (PY) signals in filopodia that directly correlate with filopodial behavior. Local PY signals are generated at distal tips of filopodia during extension and are lost during retraction. Active Src family kinases localize to the tips of filopodia, and Src activity regulates both filopodial dynamics and local PY signaling. Positive guidance cues stimulate filopodial motility by locally increasing tyrosine phosphorylation in a cell division cycle 42 (Cdc42)-dependent manner. Locally reduced Src activity on one side of the growth cone generates an asymmetry in filopodial motility and PY signaling that promotes repulsive turning, suggesting that local changes in filopodial PY levels may underlie growth cone pathfinding decisions. p21-activated kinase (PAK), a Cdc42 effector whose activity is regulated by Src phosphorylation, also localizes to the tips of extending filopodia and controls filopodial motility. Coordinated activation of cytoskeletal effector proteins by GTPase binding and Src-mediated tyrosine phosphorylation may function to produce specific growth cone behaviors in response to guidance cues.
Chromatographic Purification of Virus Particles (2009)

Abstract The application of chromatography represents an increasing trend in the field of virus purification. This article focuses on the unique constraints imposed by virus particles and how they relate to the strengths and limitations of various chromatography media. Specific attention is given to the contributions of different types of physical supports, including porous particles, monoliths, and adsorptive membranes. Media characteristics are also discussed in the context of purification process control, reproducibility, and process economics. Protocols are offered for conducting method development with size exclusion, ion exchange, hydrophobic interactions, hydroxyapatite, and bioaffinity chromatography, and guidelines are summarized for combining individual methods into integrated multistep purification procedures suitable for preparation of clinical material.
Studies on the Constituents of <i>Lupinus mutabilis </i>(Fabaceae). Isolation and Characterization of Two New Isoflavonoid Derivatives (1998)

Two new flavonoid derivatives, mutabilin (1) and mutabilein (2), were isolated from the seeds of Lupinus mutabilis. Their structures were elucidated on the basis of spectral and chemical data to be 3‘-methoxy-5-hydroxy-7-O-β-d-glucosylisoflavone and 3‘-methoxy-5,7-dihydroxyisoflavone. Keywords: Lupinus mutabilis; Fabaceae; tarwi; flavonoid glycosides; 3‘-methoxy-5-hydroxy-7-O-β-d-glucosylisoflavone, mutabilein; 3‘- methoxy-5,7-dihydroxyisoflavone, mutabilin; South American crop; food source;1H and 13C NMR; 1H−1H 2D COSY correlated H; 13C−1H 2D HMQC correlated C; 13C−1H 2D HMBC correlated C; FABMS
Dual template synthesis of a highly mesoporous SSZ-13 zeolite with improved stability in the methanol-to-olefins reaction (2012)

The dual template synthesis of zeolite SSZ-13 by use of trimethyl-adamantanammonium hydroxide and a diquaternary-ammonium mesoporogen induces considerable mesoporosity without impeding zeolite microporosity. The strongly improved accessibility of Brønsted sites in mesoporous SSZ-13 increases its stability during application as an acid catalyst in the methanol-to-olefins reaction.
Hexavalent Chromium Extraction from Soils: A Comparison of Five Methods (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHexavalent Chromium Extraction from Soils: A Comparison of Five MethodsBruce R. James, John C. Petura, Rock J. Vitale, and George R. MussolineCite this: Environ. Sci. Technol. 1995, 29, 9, 2377–2381Publication Date (Print):September 1, 1995Publication History Published online1 May 2002Published inissue 1 September 1995https://pubs.acs.org/doi/10.1021/es00009a033https://doi.org/10.1021/es00009a033research-articleACS PublicationsRequest reuse permissionsArticle Views1654Altmetric-Citations185LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene (1999)

Fibroblast growth factor 9 (FGF9), originally cloned as glial-activating factor from human glioma cells, is expressed in adult rat brain and kidney. Here we report the chromosomal localization, genomic organization, and embryonic expression pattern of the mouse Fgf9 gene. Fgf9 maps to chromosome 14 near the Ctla6 locus. The gene spans more than 34 kb and contains three exons and two introns. Translation initiation occurs in exon 1, and translation termination occurs in exon 3. Fgf9 RNA was detected during mouse embryogenesis in several tissues in which Fgf gene expression has not been previously described, including intermediate mesoderm of late-stage gastrulation, ventricular myocardium, lung pleura, skeletal myoblasts in the early limb bud, spinal cord motor neurons, olfactory bulb, and gut lumenal epithelium. Fgf9 is coexpressed with other Fgf genes in some skeletal myoblasts, in limb apical ectoderm, in craniofacial ectoderm, and in the retina, inner ear, and tooth bud. Dev Dyn 1999;216:72-88.
Identification of Alcohol Abuse Using Laboratory Tests and a History of Trauma (1984)

In a study involving 68 ambulatory patients with known alcohol problems and 68 social drinkers matched for age and sex, a questionnaire about the patients' history of trauma identified 7 out of 10 subjects with drinking problems. In contrast, abnormal values for gamma-glutamyl transferase, mean corpuscular volume, or high-density lipoproteins had only moderate sensitivity (26% to 40%) for identifying alcohol problems but excellent specificity (88% to 99%) for ruling out cases. Similar rates of sensitivity and specificity were found among 61 family practice patients. Diagnostic accuracy was improved by combining tests results, using computer-based logistic regression analysis. This study suggests that a brief questionnaire on history of trauma is valuable for the earlier detection of problem drinking in ambulatory populations, in contrast to laboratory tests, which appear to have high sensitivity only with more chronic alcoholics.
Bi-mode time-space multiplexing antenna array for multi-targets detection in automotive application (2002)

A novel antenna array scheme BTSM is proposed where time-space multiplexing technology is used and advantages of panorama and detail modes are combined. Compared with conventional MAA, this array has high capability for multi-target detection, smaller size, lower cost and smaller computation. BTSM FMCW radar systems will allow lane prediction and the classification of objects, thus making possible the intelligent interpretation of traffic scenes.