gebhart/patrepeval huggingface dataset:
The Endoscopic Multiple-diameter Bougie - Clinical Results after One Year of Application (1983)

A new technique for dilation of the upper gastrointestinal tract permits complete endoscopic control of the whole procedure for the first time. 113 dilations have been carried out in 37 patients within a period of 15 months. The endoscopic guidance of the multiple diameter bougie positively excludes perforation resulting from the bougie's going the wrong way. With the steerable tip of the endoscope, kinking can be overcome and stenoses down to the duodenum can be dilated.
Energy transfer in micellar systems. Steady state and time resolved luminescence of aqueous micelle solubilized naphthalene and terbium chloride (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnergy transfer in micellar systems. Steady state and time resolved luminescence of aqueous micelle solubilized naphthalene and terbium chlorideJose R. Escabi-Perez, Faruk Nome, and Janos H. FendlerCite this: J. Am. Chem. Soc. 1977, 99, 24, 7749–7754Publication Date (Print):November 1, 1977Publication History Published online1 May 2002Published inissue 1 November 1977https://pubs.acs.org/doi/10.1021/ja00466a001https://doi.org/10.1021/ja00466a001research-articleACS PublicationsRequest reuse permissionsArticle Views300Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
IS <i>6110</i> -Mediated Deletions of Wild-Type Chromosomes of <i>Mycobacterium tuberculosis</i> (1999)

The ipl locus is a site for the preferential insertion of IS6110 and has been identified as an insertion sequence, IS1547, in its own right. Various deletions around the ipl locus of clinical isolates of Mycobacterium tuberculosis were identified, and these deletions ranged in length from several hundred base pairs up to several kilobase pairs. The most obvious feature shared by these deletions was the presence of an IS6110 copy at the deletion sites, which suggested two possible mechanisms for their occurrence, IS6110 transposition and homologous recombination. To clarify the mechanism, an investigation was conducted; the results suggest that although deletion transpositionally mediated by IS6110 was a possibility, homologous recombination was a more likely one. The implications of such chromosomal rearrangements for the evolution of M. tuberculosis, for IS6110-mediated mutagenesis, and for the development of genetic tools are discussed. The deletion of genomic DNA in isolates of M. tuberculosis has previously been noted at only a few sites. This study examined the deletional loss of genetic material at a new site and suggests that such losses may occur elsewhere too and may be more prevalent than was previously thought. Distinct from the study of laboratory-induced mutations, the detailed analysis of clinical isolates, in combination with knowledge of their evolutionary relationships to each other, gives us the opportunity to study mutational diversity in isolates that have survived in the human host and therefore offers a different perspective on the importance of particular genetic markers in pathogenesis.
Feasibility study of RSFQ-based self-routing nonblocking digital switches (1997)

This paper describes the results of a preliminary analysis of ultra-fast low-power superconductor digital switches based on Rapid Single-Flux-Quantum (RSFQ) technology. In particular, RSFQ-based crossbar, Batcher-banyan, and shared bus switching cores have been considered, and the possible parameters of these circuits have been estimated. The results show that the proposed RSFQ digital switches with overall throughput of 7.5 Tbps operating at an internal clock frequency of /spl sim/60 GHz and dissipating very little power could effectively compete with their semiconductor and photonic counterparts.
The use of a wearable camera, SenseCam, as a pictorial diary to improve autobiographical memory in a patient with limbic encephalitis: A preliminary report (2007)

This case study describes the use of a wearable camera, SenseCam, which automatically captures several hundred images per day, to aid autobiographical memory in a patient, Mrs B, with severe memory impairment following limbic encephalitis. By using SenseCam to record personally experienced events we intended that SenseCam pictures would form a pictorial diary to cue and consolidate autobiographical memories. After wearing SenseCam, Mrs B plugged the camera into a PC which uploaded the recorded images and allowed them to be viewed at speed, like watching a movie. In the control condition, a written diary was used to record and remind her of autobiographical events. After viewing SenseCam images, Mrs B was able to recall approximately 80% of recent, personally experienced events. Retention of events was maintained in the long-term, 11 months afterwards, and without viewing SenseCam images for three months. After using the written diary, Mrs B was able to remember around 49% of an event; after one month with no diary readings she had no recall of the same events. We suggest that factors relating to rehearsal/re-consolidation may have enabled SenseCam images to improve Mrs B's autobiographical recollection.
Khellin and Visnagin, Furanochromones from <i>Ammi visnaga</i> (L.) Lam., as Potential Bioherbicides (2016)

Plants constitute a source of novel phytotoxic compounds to be explored in searching for effective and environmentally safe herbicides. From a previous screening of plant extracts for their phytotoxicity, a dichloromethane extract of Ammi visnaga (L.) Lam. was selected for further study. Phytotoxicity-guided fractionation of this extract yielded two furanochromones, khellin and visnagin, for which herbicidal activity had not been described before. Khellin and visnagin were phytotoxic to model species lettuce (Lactuca sativa) and duckweed (Lemna paucicostata), with IC<sub>50</sub> values ranging from 110 to 175 μM. These compounds also inhibited the growth and germination of a diverse group of weeds at 0.5 and 1 mM. These weeds included five grasses [ryegrass (Lolium multiflorum), barnyardgrass (Echinocloa crus-galli), crabgrass (Digitaria sanguinalis), foxtail (Setaria italica), and millet (Panicum sp.)] and two broadleaf species [morningglory (Ipomea sp.) and velvetleaf (Abutilon theophrasti)]. During greenhouse studies visnagin was the most active and showed significant contact postemergence herbicidal activity on velvetleaf and crabgrass at 2 kg active ingredient (ai) ha<sup>-1</sup>. Moreover, its effect at 4 kg ai ha<sup>-1</sup> was comparable to the bioherbicide pelargonic acid at the same rate. The mode of action of khellin and visnagin was not a light-dependent process. Both compounds caused membrane destabilization, photosynthetic efficiency reduction, inhibition of cell division, and cell death. These results support the potential of visnagin and, possibly, khellin as bioherbicides or lead molecules for the development of new herbicides.
Integrin αvβ1 promotes infection by human metapneumovirus (2009)

Human metapneumovirus (hMPV) is a recently described paramyxovirus that causes lower respiratory infections in children and adults worldwide. The hMPV fusion (F) protein is a membrane-anchored glycoprotein and major protective antigen. All hMPV F protein sequences determined to date contain an Arg-Gly-Asp (RGD) sequence, suggesting that F engages RGD-binding integrins to mediate cell entry. The divalent cation chelator EDTA, which disrupts heterodimeric integrin interactions, inhibits infectivity of hMPV but not the closely related respiratory syncytial virus (RSV), which lacks an RGD motif. Function-blocking antibodies specific for alphavbeta1 integrin inhibit infectivity of hMPV but not RSV. Transfection of nonpermissive cells with alphav or beta1 cDNAs confers hMPV infectivity, whereas reduction of alphav and beta1 integrin expression by siRNA inhibits hMPV infection. Recombinant hMPV F protein binds to cells, whereas Arg-Gly-Glu (RGE)-mutant F protein does not. These data suggest that alphavbeta1 integrin is a functional receptor for hMPV.
What are the real differences of children's and adults' web search (2011)

We present first results of a logfile analysis on web search engines for children. The aim of this research is to analyse fundamental facts about how children's web search behaviour differs from that of adults. We show differences to previous results, which are often based on small lab experiments. Our large-scale analysis suggests that children search queries are more information-oriented and shorter on average. Children indeed make a lot of spelling errors and often repeat searches and revisit web pages.
Use of Interference to Extinguish Reflection of Light from Glass (1939)

The phenomena of interference of light rays reflected from the two boundaries of a thin film cause the intensity ${I}_{R}$ of the resultant light to be greater or less than the intensity of the individual rays. The value of ${I}_{R}$ is determined by (a) the refractive index of the film, ${n}_{1}$, and the substance on which the film is deposited, ${n}_{g}$, (b) the thickness of the film, (c) the angle of incidence at which light strikes the film, (d) the wave-length of the light. The conditions necessary to obtain extinction of reflected light are described. In the case of monochromatic perpendicular light ${I}_{R}=0$ when ${n}_{1}={{n}_{g}}^{\frac{1}{2}}$ and the thickness $t$ is given by $t=\frac{0.25\ensuremath{\lambda}(2a+1)}{2}$ where $a$ is zero or an integer. The technique of building films which have the required values of ${n}_{1}$ and $t$ is described. The films are made by building up monomolecular layers, each layer consisting of 50 percent cadmium arachidate and 50 percent arachidic acid. The film is then soaked in alcohol which dissolves the arachidic acid and leaves a skeleton of cadmium arachidate. The refractive index of the skeleton is determined by the amount of arachidic acid which has been removed from the film. Since the interstices are of molecular size there is no appreciable scattering of the reflected light.
An unusual presentation of parathyroid adenoma--a case report. (2005)

A case of intrathyroid parathyroid adenoma which clinically and cytologically mimicked thyroid tumor is presented. The patient was normocalcemic inspite of clinical and radiological features suggestive of hyperparathyroid bone disease. The adenoma showed an area of infarction presumably accounting for the normocalcemic primary hyperparathyroidism. The case is reported for its unusual presentation.
Birth after reimplantation of a human embryo [letter] (1978)

We wish to report that 1 of our patients a 30-year-old nulliparous married woman was safely delivered by cesarean section on July 25 1978 of a normal healthy infant girl weighing 2700 g. The patient had been referred to 1 of us (P.C.S.) in 1976 with a history of 9 years infertility tubal occlusions and unsuccessful salpingostomies done in 1970 with excision of the ampullae of both oviducts followed by persistent tubal blockages. Laparoscopy in February 1977 revealed grossly distorted tubal remnants with occlusion and peritubal and ovarian adhesions. Laparotomy in August 1977 was done with excision of the remains of both tubes adhesolysis and suspension of the ovaries in good position for oocyte recovery. Pregnancy was established after laparoscopic recovery of an oocyte on November 10 1977 in-vitro fertilization and normal cleavage in culture media and the reimplantation of the 8-cell embryo into the uterus 2 1/2 days later. Amiocentesis at 16 weeks pregnancy revealed normal alpha-fetoprotein levels with no chromosome abnormalities in a 46 XX fetus. On the day of delivery the mother was 38 weeks and 5 days by dates from her last menstrual period and she had preeclamptic toxemia. Blood-pressure was fluctuating around 140/95 edema involved both legs up to knee level together with the abdomen back hands and face; the blood-uric-acid was 390 mcmol/l and albumin 0.5 g/l of urine. Ultrasonic scanning and radiographic appearances showed that the fetus had grown slowly for several weeks from week 30. Blood-estriols and human placental lactogen levels also dropped below the normal levels during this period. However the fetus grew considerably during the last 10 days before delivery while placental function improved greatly. On the day of delivery the biparietal diameter had reached 9.6 cm and 5 ml of amniotic fluid was safely removed under sonic control. The lecithin:sphingomyelin ratio was 3.9:1 indicative of maturity and a low risk of the respiratory-distress syndrome. We hope to publish further medical and scientific details in your columns at a later date. (full text)
Broadband CMOS-compatible SOI temperature insensitive Mach-Zehnder interferometer (2015)

We propose an improved design approach for athermal silicon-on-insulator Mach-Zehnder interferometers to extend their spectral range with minimal temperature sensitivity. We demonstrate that the device designed following the improved approach has a near-zero temperature sensitivity (2.5 pm/K) over more than 60 nm spectral range near 1550 nm.
After the Trade Is Made: Processing Securities Transactions (1986)

Now completely updated, this classic guide to the mechanics of securities processing reflects the changes that have taken place in recent years as a result of new products, technological breakthroughs and the globalization of the securities industry.
Controlled Drug Delivery of Ph Dependent Soluble Drug-Pindolol (1994)

Pindolol, a pH dependent soluble beta adrenoceptor blocker has been formulated into a controlled drug delivery system. Drug pellets were prepared by extrusion spheronization technique. These were coated with different retardant polymers, namely ethylcellulose and Eudragit RS 100. The effect of different variables such as coating level and pH of dissolution medium have been studied. Drug release from pellets were found to be influenced by the pH of the dissolution medium. A flux release of the drug in the acidic buffer was observed from pellets coated with these polymers. To avoid this flux, a top coat using different pH sensitive polymers, namely Hydroxypropylmethyl cellulose phthalate (HPMCP 55) and Eudragit S 100 was successfully attempted and the drug release from the pellets was modified.
The Effects of b-hydroxy b-methylbutyrate on Apoptotic Signaling and Recovery Following Disuse in Aged Rat Extensor Digitorum Longus Muscle (2010)

INTRODUCTION: Prolonged bed rest or muscle immobilization causes a rapid loss of muscle mass and force output. Coupled with an increase in apoptotic signaling, the effects of muscle disuse are much more prevalent in aging populations. b-hydroxy b-methylbutyrate (HMB), a leucine metabolite has shown to minimize muscle loss during cancer cachexia and reduce the depression of protein synthesis in murine myotubes in response to apoptotic stimuli. Therefore, HMB might be a potential therapeutic remedy for disuse muscle atrophy and apoptotic signaling in aging. PURPOSE: To determine if HMB reduces apoptotic signaling and improves muscle recovery after disuse atrophy in aged rats. METHODS: Atrophy was induced in the extensor digitorum longus by 14d of hindlimb suspension in aged (34 mo) male Fisher Brown Norway 344 rats. The rats were released from hindlimb suspension and allowed a 14d recovery. The rats were gavaged daily with 1mL of 170mg HMB or water 7d prior to hindlimb suspension, during hindlimb suspension and throughout the recovery period. RESULTS: A significant decrease in the mass of the extensor digitorum longus was shown following hindlimb suspension. Though HMB supplementation did not reduce the effects muscle atrophy during hindlimb suspension, it did improve the recovery of muscle mass by 11.5% and force output by 8.2% in the aged rats compared to the water fed controls. HMB also appeared to reduce the concentrations of cleaved caspase-3, procaspse-3, Bax and Bcl-2 and reduce the number of TUNEL positive nuclei in extensor digitorum longus muscles following recovery from hindlimb suspension. CONCLUSION: HMB appears to improve muscle recovery following disuse atrophy in aged rats. This appears to be due, at least in part by suppressing the apoptotic signaling of the intrinsic pathway.
A knowledge-based system for highway network extraction (1988)

A knowledge-based system has been set up to extract highway networks automatically from Landsat thematic mapper (TM) imagery. The system was developed using image processing algorithms and some artificial intelligence techniques. It inputs raw TM data and outputs an interpreted image clearly identifying highway and road networks. The main algorithms in the system are discussed in detail, results are presented, and features of the system are examined. Landsat TM images of study areas in Toronto, Canada, are presented by way of illustration.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Retinal Protective Effects of Resveratrol via Modulation of Nitric Oxide Synthase on Oxygen-induced Retinopathy (2010)

In conclusion, resveratrol appeared to exert retinal protective effects via modulation of NO-mediated mechanism in in vivo and in vitro OIR models.
Experience of Clinical Use of the Odstock DroppedFoot Stimulator (1997)

The Odstock dropped foot stimulator (ODFS) is a simple functional electrical stimulation (FES) device for the correction of dropped foot. Improved reliability, fine control of stimulation parameters, and careful application and follow-up have let to 86% compliance. Data on 56 patients (50 patients with hemiplegia, 5 patients with multiple sclerosis, and 1 patient with spinal cord injury) who have used the system for between 6 and 18 months are presented and show a statistically significant increase in walking speed with the stimulator at 3 months of 14% (p < 0.001); decreased effort of walking, measured as physiological cost index (PCI), of 37% (p < 0.001); and statistically significant improvement in functional mobility tests and questionnaires. No statistically significant carryover was seen although 3 patients had sufficient improvement in active ankle control and gait parameters to no longer need the stimulator. Six patients who used the stimulator all day every day had a problem with skin irritation, which we have not yet been able to solve. Two patients discontinued use after experiencing increased spasticity in the calf.
Development of user interface and drawing tools in digital image processing system for intracellular fluorescent dye concentrations of living cells (2002)

In our system developed in Visual C++ for images with intracellular fluorescent dye concentrations of living cells after the boundaries and labels are drawn for all living cells, the new image is pushed into the stack pointer for the purpose of redo function and the window is updated. For the user interface, different buttons and their control algorithms have been tested. In our program we used some special control algorithms to ensure that the user gets less chance to make an error operation. Drawing line can split joined objects and Regions-of-Interest can be selected or removed by drawing a rectangle or an ellipse. Once we select any part of an image by drawing rectangle or ellipse, the cutting button and the file generation button are enabled together with the clear button. Such an approach allows the user not to be concerned so much which operation is suitable at any time and the continuous undo and redo operation encourage the user to perform whatever operation is suitable at any time without being afraid of losing information. Finally the reminding messages will guide the user how to perform operation of the system correctly and to retrieve any removed data.
Progress and Current Status of Percutaneous Aortic Valve Replacement: Results of Three Device Generations of the CoreValve Revalving System (2008)

In experienced hands, percutaneous aortic valve replacement with the CoreValve system for selected patients with severe aortic valve stenosis has a high acute success rate associated with a low periprocedural mortality/stroke rate as well as remarkable clinical and hemodynamic improvements, which persist over time. Additional studies are now required to confirm these findings, particularly head-to-head comparisons with surgical valve replacement in different risk populations.
Über En‐synthesen mit Singulett‐Sauerstoff [1] II. Die Farbstoff‐sensibilisierte Photooxygenierung von (—)‐Thujopsen und die Stereochemie der dargestellten Thujopsanole (1970)

Abstract The dye‐sensitized photooxygenation of (–)‐thujopsene ( 1 ) leads to two allyl hydroperoxides 16 and 17 (ratio 2:1). From the structure of the corresponding alcohols 2 and 3 it is possible to demostrate the complete stereospecificity of the addition of 1 Δ g ‐oxygen to the acceptor system. In this way it is shown that 1 exists in only one conformation in solution. The production of the rearranged product 23 can be explained by Hock fission from the allyl hydroperoxides 16 or 17 following the Criegee mechanism. Under the epoxidation conditions 1 is converted mainly to the two new odorous substances (–)‐3‐thujopsanone ( 4 ) and (–)‐3‐isothujopsanone ( 5 ). A series of sesquiterpenes with the thujopsane skeleton is also described, all of which have been intercorrelated.
Hydrogenated polybutadiene–polymethyl methacrylate (HPB–PMMA) block copolymer. I. Synthesis of polybutadiene–polymethyl methacrylate (PB–PMMA) block copolymer (1993)

Abstract To get hydrogenated polybutadiene‐polymethyl methacrylate (HPB‐b‐PMMA) block copolymer to be used as a compatibilizer for blends of polyolefin/polar polymer, PB‐b‐PMMA was synthesized by anionic‐free radical mechanism transformation polymerization. Selective extraction, gradient elution thin layer chromatography, and oil‐oil emulsion separation techniques were tried to attempt to separate the copolymerization products. Hydrogenation of the PB sequence in PB‐b‐PMMA yielded HPB‐b‐PMMA. The compatibilizing function of PB‐b‐PMMA was shown in blending experiments. © 1993 John Wiley & Sons, Inc.
An Efficient Scheme for Real-time Information Storage and Retrieval Systems: A Hybrid Approach (2017)

Information storage and retrieval is the fundamental requirement for many real-time applications. These systems demand that data should be sorted all the time, real-time insertion, deletion and searching should be supported and system must support dynamic entries. These systems require search operations to be performed from massive databases implemented by various data structures. The common data structures used by these systems are stack, queue or linked list all having their own limitations. The biggest advantage of using stack is that binary search can be performed on it easily while on the other hand insertion and deletion of nodes involves more processing overhead. In linked list, insertion and deletion of nodes is easier but searching operation involves more processing overhead as binary search cannot be performed efficiently on it. In this paper, a hybrid solution is presented for such systems, which provides efficient insertion, deletion and searching operations. Results show the effectiveness of the proposed approach as it outperforms the existing techniques used by these systems.