gebhart/patrepeval huggingface dataset:
Neutrosophic Regular Filters And Fuzzy Regular Filters In Pseudo-Bci Algebras (2017)

Neutrosophic set is a new mathematical tool for handling problems involving imprecise, indeterminacy and inconsistent data. Pseudo-BCI algebra is a kind of non-classical logic algebra in close connection with various non-commutative fuzzy logics. Recently, we applied neutrosophic set theory to pseudo-BCI algebras. In this paper, we study neutrosophic filters in pseudo-BCI algebras. The concepts of neutrosophic regular filter, neutrosophic closed filter and fuzzy regular filter in pseudo-BCI algebras are introduced, and some basic properties are discussed. Moreover, the relationships among neutrosophic regular filter, fuzzy filters and anti-grouped neutrosophic filters are presented, and the results are proved: a neutrosophic filter (fuzzy filter) is a neutrosophic regular filter (fuzzy regular filter), if and only if it is both a neutrosophic closed filter (fuzzy closed filter) and an anti-grouped neutrosophic filter (fuzzy anti-grouped filter).
Evaluation of the Ni<sub>3</sub>Al Base Alloys IC221 and IC218LZr (1992)

N&Al-base alloys are being considered for a range of applications, where their high strength at elevated temperatures can be utilized. This paper summarizes the results of physical metallurgy evaluations of X221 and IC218LZr which are alloys suitable for commercial applications.
Tacky Elastomers to Enable Tear‐Resistant and Autonomous Self‐Healing Semiconductor Composites (2020)

Abstract Mechanical failure of π‐conjugated polymer thin films is unavoidable under cyclic loading conditions, due to intrinsic defects and poor resistance to crack propagation. Here, the first tear‐resistant and room‐temperature self‐healable semiconducting composite is presented, consisting of conjugated polymers and butyl rubber elastomers. This new composite displays both a record‐low elastic modulus (<1 MPa) and ultrahigh deformability with fracture strain above 800%. More importantly, failure behavior is not sensitive to precut notches under deformation. Autonomous self‐healing at room temperature, both mechanical and electronic, is demonstrated through the physical contact of two separate films. The composite film also shows device stability in the ambient environment over 5 months due to much‐improved barrier property to both oxygen and water. Butyl rubber is broadly applicable to various p‐type and n‐type semiconducting polymers for fabricating self‐healable electronics to provide new resilient electronics that mimic the tear resistance and healable property of human skin.
Remote maintenance for IM (1999)

With the availability of new tools for interacting, handling and analyzing information about product state (sensor, computer, and communication technologies), the development of maintenance engineering for Product Life Cycle (PLC) support is becoming feasible. This paper describes an information-centered approach to maintenance based on criteria of PLC optimization. Remote maintenance is considered as a distributed process incorporating remote product monitoring, computerized decision-making, and online maintenance guidance. The paper presents demands of Inverse Manufacturing on PLC modeling, model input parameters and criteria to generate optimal maintenance actions. A supporting information infrastructure system for remote maintenance is discussed.
A Source Routing Algorithm for LEO Satellite Networks (2006)

One research challenge in low earth orbit (LEO) satellite networks is to develop specialized and efficient routing algorithms. Based on datagram routing algorithm (DRA), a new routing algorithm, namely source routing algorithm (SRA), for LEO satellite networks is presented. Compared with DRA, it reduces computation overhead greatly while keeping the same overall performance. By the algorithm, the path with minimum propagation delay is discovered at the source satellite and stored in packet header, and then the packet is forwarded to its destination by intermediate nodes according to the path. Finally, the algorithm performance is evaluated through simulation and its computation complexity is analyzed to validate the efficiency of SRA.
GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro (2016)

Recent studies showed that GPR30, a seven-transmembrane G-protein-coupled receptor, is a novel estrogen receptor (ER) that mediates some biological events elicited by estrogen in several types of cancer cells. However, its physiological or pathological role in vivo is unclear. Here, we show that GPR30 knockout (GPRKO) female mice were protected from high-fat diet (HFD)-induced obesity, blood glucose intolerance, and insulin resistance. The decreased body weight gain in GPRKO female mice is due to the reduction in body fat mass. These effects occurred in the absence of significant changes in food intake, intestinal fat absorption, triglyceride metabolism, or energy expenditure. However, GPR30 had no significant metabolic effects in male mice fed the HFD and both sexes of mice fed a chow diet. Further, GPR30 expression levels in fat tissues of WT obese female mice were greatly increased, whereas ERα and β expression was not altered. Deletion of GPR30 reduced adipogenic differentiation of adipose tissue-derived stromal cells. Conversely, activation of GPR30 enhanced adipogenic differentiation of 3T3-L1 preadipocytes. These findings provide evidence for the first time that GPR30 promotes adipogenesis and therefore the development of obesity in female mice exposed to excess fat energy.
Heavy Metal Polluted Soils: Effect on Plants and Bioremediation Methods (2014)

Soils polluted with heavy metals have become common across the globe due to increase in geologic and anthropogenic activities. Plants growing on these soils show a reduction in growth, performance, and yield. Bioremediation is an effective method of treating heavy metal polluted soils. It is a widely accepted method that is mostly carried out in situ ; hence it is suitable for the establishment/reestablishment of crops on treated soils. Microorganisms and plants employ different mechanisms for the bioremediation of polluted soils. Using plants for the treatment of polluted soils is a more common approach in the bioremediation of heavy metal polluted soils. Combining both microorganisms and plants is an approach to bioremediation that ensures a more efficient clean-up of heavy metal polluted soils. However, success of this approach largely depends on the species of organisms involved in the process.
Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K<sup>+</sup>]<sub>o</sub>regulation (1997)

The neuronal K-Cl cotransporter isoform (KCC2) was functionally expressed in human embryonic kidney (HEK-293) cell lines. Two stably transfected HEK-293 cell lines were prepared: one expressing an epitope-tagged KCC2 (KCC2-22T) and another expressing the unaltered KCC2 (KCC2-9). The KCC2-22T cells produced a glycoprotein of approximately 150 kDa that was absent from HEK-293 control cells. The 86Rb influx in both cell lines was significantly greater than untransfected control HEK-293 cells. The KCC2-9 cells displayed a constitutively active 86Rb influx that could be increased further by 1 mM N-ethylmaleimide (NEM) but not by cell swelling. Both furosemide [inhibition constant (Ki) approximately 25 microM] and bumetanide (Ki approximately 55 microM) inhibited the NEM-stimulated 86Rb influx in the KCC2-9 cells. This diuretic-sensitive 86Rb influx in the KCC2-9 cells, operationally defined as KCC2 mediated, required external Cl- but not external Na+ and exhibited a high apparent affinity for external Rb+(K+) [Michaelis constant (Km) = 5.2 +/- 0.9 (SE) mM; n = 5] but a low apparent affinity for external Cl- (Km > 50 mM). On the basis of thermodynamic considerations as well as the unique kinetic properties of the KCC2 isoform, it is hypothesized that KCC2 may serve a dual function in neurons: 1) the maintenance of low intracellular Cl- concentration so as to allow Cl- influx via ligand-gated Cl- channels and 2) the buffering of external K+ concentration ([K+]o) in the brain.
<i>SQUAMOSA</i> Promoter‐Binding Protein‐Like Transcription Factors: Star Players for Plant Growth and Development (2010)

SQUAMOSA Promoter-Binding Protein-Like (SPL) genes encode plant-specific transcription factors that play important roles in plant phase transition, flower and fruit development, plant architecture, gibberellins signaling, sporogenesis, and response to copper and fungal toxins. In Arabidopsis, many SPL genes are post-transcriptionally regulated by the microRNA (miRNA) miR156, among which AtSPL9 in turn positively regulates the expression of the second miRNA miR172. This miR156-AtSPL9-miR172 regulatory pathway plays critical roles during juvenile to adult leaf development and the miR156-SPLs feedback interaction persists all through the plant development, which may be conserved in other plants. In the present paper, we provide a concise review on the most recent progress in the regulatory mechanisms associated with plant SPL transcription factors, especially in relation to miRNAs. The potential application of these discoveries in agriculture is briefly discussed.
Accelerated healing in <scp>NONcNZO10/LtJ</scp> type 2 diabetic mice by<scp> FGF</scp>‐1 (2015)

The development of novel therapies to treat chronic diabetic ulcers depends upon appropriate animal models for early stage investigation. The NONcNZO10/LtJ mouse is a new polygenic strain developed to more realistically model human metabolic syndrome and obesity-induced type 2 diabetes; however, detailed wound healing properties have not been reported. Herein, we describe a quantitative wound healing study in the NONcNZO10/LtJ mouse using a splinted excisional wound. The rate of wound healing is compared to various controls, and is also quantified in response to topical administration of normal and mutant fibroblast growth factor-1 (FGF-1). Quantitation of reepithelialization shows that the diabetic condition in the NONcNZO10/LtJ mouse is concomitant with a decreased rate of dermal healing. Furthermore, topical administration of a FGF-1/heparin formulation effectively accelerates reepithelialization. A similar acceleration can also be achieved by a stabilized mutant form of FGF-1 formulated in the absence of heparin. Such accelerated rates of healing are not associated with any abnormal histology in the healed wounds. The results identify the NONcNZO10/LtJ mouse as a useful model of impaired wound healing in type 2 diabetes, and further, identify engineered forms of FGF-1 as a potential “second-generation” therapeutic to promote diabetic dermal wound healing.
Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression. (1990)

To delineate segments of the genome of the human protozoan parasite Leishmania major necessary for replication and expression, we developed a vector (pR-NEO) which can be reproducibly introduced into L. major. This DNA was derived from a 30-kilobase extrachromosomal amplified DNA bearing the dihydrofolate reductase-thymidylate synthase gene, with the coding region for neomycin phosphotransferase substituted for that of dihydrofolate reductase-thymidylate synthase and a bacterial origin of replication and selectable marker added. G418-resistant lines were obtained at high efficiency by electroporation of pR-NEO (approaching 10(-4) per cell), while constructs bearing an inverted neo gene or lacking Leishmania sequences did not confer resistance. pR-NEO replicated in L. major and gave rise to correctly processed transcripts bearing the trans-spliced miniexon. Molecular karyotype analysis showed that in some lines pR-NEO DNA exists exclusively as an extrachromosomal circle, a finding supported by the rescue of intact pR-NEO after transformation of Escherichia coli. These data genetically localize all elements required in cis for DNA replication, transcription, and trans splicing to the Leishmania DNA contained within pR-NEO DNA and signal the advent of stable transfection methodology for addressing molecular phenomena in trypanosomatid parasites.
Biological indicators for steam sterilization: characterization of a rapid biological indicator utilizing<i>Bacillus stearothermophilus</i>spore-associated alpha-glucosidase enzyme (1998)

The alpha-glucosidase enzyme was isolated from vegetative cells and spores of Bacillus stearothermophilus, ATCC 7953. Spore-associated enzyme had a molecular weight of approximately 92,700, a temperature optimum of 60 degrees C, and a pH optimum of 7.0-7.5. The enzyme in crude aqueous spore extract was stable for 30 min up to a temperature of 65 degrees C, above which the enzyme was rapidly denatured. The optimal pH for stability of the enzyme was approximately 7.2. The alpha-glucosidase in crude vegetative cell extract had similar characteristics to the spore-associated enzyme but its molecular weight was 86,700. The vegetative cell and spore-associated enzymes were cross-reactive. The enzymes are postulated to derive from a single gene product, which undergoes modification to produce the spore-associated form. The location of alpha-glucosidase in the spore coats (outside the spore protoplast) is consistent with the location of most enzymes involved in activation, germination and outgrowth.
Clinical Information Needs of the Allopathic Medical Practitioners in Developing Country, India: A Descriptive Analysis with Workplace. (2014)

Clinical Information need is an important factor for the practicing allopathic medical practitioners. This study aim is to identify the practitioners’ clinical information needs level and analysed with their experience and correlate with gender, educational qualification and workplace. Experience is classified into six categories like; 0-5years, 6-10years, 11-15years, 16-20years, 21-25years and above 25 years. Survey method is adopted and pretested questionnaire is used as a tool for data collection. Salem, Erode, Trippur, Coimbatore, and the Nilagari districts medical practitioners are used for this study. Among the 5290 samples, 10% (529) practitioners are selected by Stratified Proportionate Random Sampling (SPRS) method. One-way ANOVA, average weighted score plots and post-hoc tests are used for identification of the significant groups of the medical practitioners. From the result, experience is one of the most influenced factors of the allopathic medical practitioners clinical information needs.
Fractional flow reserve in acute coronary syndromes: A review (2014)

Fractional flow reserve (FFR) assessment provides anatomical and physiological information that is often used to tailor treatment strategies in coronary artery disease. Whilst robust data validates FFR use in stable ischaemic heart disease, its use in acute coronary syndromes (ACS) is less well investigated. We critically review the current data surrounding FFR use across the spectrum of ACS including culprit and non-culprit artery analysis. With adenosine being conventionally used to induce maximal hyperaemia during FFR assessment, co-existent clinical conditions may preclude its use during acute myocardial infarction. Therefore, we include a current review of instantaneous wave free ratio as a novel vasodilator independent method of assessing lesion severity as an alternative strategy to guide revascularisation in ACS.
Facile one-pot synthesis of mesoporous hierarchically structured silica/carbon nanomaterials (2012)

Mesoporous silica/carbon nanomaterials with various hierarchical structures have been fabricated by a one-pot approach. Polymer/silica/surfactant (PSS) composites are first prepared by the co-sol–gel process of TEOS and resorcinol–formaldehyde precursor in the presence of CTAB. The PSS morphologies could be tuned by simply altering the content of ethanol in solution.
Wireless measurement of temperature using surface acoustic waves sensors (2004)

Surface acoustic wave (SAW) devices can be used as wireless sensor elements, called SAW transponders, for measuring physical quantities such as temperature that do not need any power supply and may be accessed wirelessly. A complete wireless sensor system consists of one or more such SAW transponders and a local radar transceiver. The SAW transponder receives an RF burst in the VHF/UHF band transmitted by the radar transceiver. The reader unit performs a radar measurement of the impulse response of the SAW transponder via a high-frequency electromagnetic radio link. A temperature variation changes the SAW velocity and thereby the response pattern of the SAW device. By analyzing the time delay between backscattered pulses with different time delays we get a rough estimation of the temperature of the SAW transponder. By using this information the ambiguity of +/-2pi in the phase differences between the pulses can be eliminated, which provides an overall and unambiguous temperature resolution of +/-0.2 degrees C.
The Quantitative Analysis of Alkyllithium Compounds<sup>1</sup> (1944)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Quantitative Analysis of Alkyllithium Compounds1Henry Gilman and A. H. HaubeinCite this: J. Am. Chem. Soc. 1944, 66, 9, 1515–1516Publication Date (Print):September 1, 1944Publication History Published online1 May 2002Published inissue 1 September 1944https://pubs.acs.org/doi/10.1021/ja01237a031https://doi.org/10.1021/ja01237a031research-articleACS PublicationsRequest reuse permissionsArticle Views2026Altmetric-Citations374LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Statistical Approach to the Effective Economic Modeling and Portfolio Selection of Unconventional Resource Opportunities (2009)

Abstract Many firms are pursuing unconventional resource opportunities across the globe as a low risk vehicle for growth. Unfortunately, not all resource plays have met the expectations of this low risk model. Some opportunities are very product price dependent and others are both price and technology dependent. This paper provides an overview of the North American industry's use of statistically based production and EUR type curves to assess new opportunities and ongoing developments. This paper highlights an alternative methodology for the selection of future unconventional resource opportunities based on their corporate definition of materiality and the use of analog production type curves. This methodology focuses on appropriate production type curves rather than reservoir models for tight gas sands and shale gas opportunities. Examples of production type curves will be presented to demonstrate the need to align these curves to the geological facies, the well type (vertical versus horizontal), and the completion technology (fracture stimulation size, fracture fluids, and the number of fracture stages). The appropriate selection from the myriad of unconventional resource opportunities available is often a critical component to achieving corporate goals. Pick the wrong opportunity and even with superb execution, the returns are limited. Selecting the right unconventional resource opportunity enhances your probability to please shareholders. The methodology is similar, yet unique from traditional basin analysis in its use of Common Risk Segment (aka ‘traffic light') maps and production type curves versus a range of reserves in a prospect.
Secondary Structure and Membrane Topology of the Full‐Length Dengue Virus NS4B in Micelles (2016)

Dengue virus nonstructural protein 4B (NS4B) is a membrane protein consisting of 248 residues with a crucial role in virus replication and interference with the host innate immunity. The dengue virus serotype 3 NS4B was reconstituted into lyso-myristoyl phosphatidylglycerol (LMPG) micelles. Backbone resonance assignment of NS4B was obtained using conventional solution NMR experiments. Further studies suggested that NS4B contained eleven helices and six of them form five potential transmembrane regions. This study provides atomic level information for an important drug target to control flavivirus infections.
ReNet: A Recurrent Neural Network Based Alternative to Convolutional Networks (2015)

In this paper, we propose a deep neural network architecture for object recognition based on recurrent neural networks. The proposed network, called ReNet, replaces the ubiquitous convolution+pooling layer of the deep convolutional neural network with four recurrent neural networks that sweep horizontally and vertically in both directions across the image. We evaluate the proposed ReNet on three widely-used benchmark datasets; MNIST, CIFAR-10 and SVHN. The result suggests that ReNet is a viable alternative to the deep convolutional neural network, and that further investigation is needed.
Compiling Packet Programs to Reconfigurable Switches (2020)

A critical step in P4 compilation is finding a feasible and efficient mapping of the high-level P4 source code constructs to the physical resources exposed by the underlying hardware, while meeting data and control flow dependencies in the program. In this paper, we take a new look at the algorithmic aspects of this problem, with the motivation to understand the fundamental theoretical limits and obtain better P4 pipeline embeddings, and to speed up practical P4 compilation times. We report mixed results: we find that P4 compilation is computationally intractable even in a severely relaxed formulation, and there is no hope for a tractable approximation of arbitrary precision, while the good news is that, despite its inherent complexity, P4 compilation is approximable in quasi-linear time with a small constant bound even after removing most of the relaxations from the model.
[B-chain shortening of matrix-bound insulin by pepsin, I:Preparation and properties of bovine des-pentapeptide(B26-30) insulin (suthor's transl)]. (1975)

Insulin was adsorbed to a strongly acidic ion exchanger and incubated with pepsin. The digestion of the matrix-bound insulin was found to be restricted to the cleavage of the peptide bond between phenylalanine-B25 and tyrosine-B26. Factionation of the reaction products was achieved by gel filtrationon Sephadex G-50 at pH 8 where des-pentapeptide(B26-30)-insulin does not aggregate. Another way to purify this compound was ion-exchange chromatography, which was easy due to the loss of one positive charge on the modified insulin. Crystallization could be achieved in a phenol-containing buffer. Des-pentapeptide(B26-30)-insulin was found to be molecularly uniform by electrophoresis at pH 2.2 and 8.6, thin-layer chromatography, performic acid oxidation, end group analysis and amino acid analysis. The CD-spectrum indicated conformational changes compared to insulin. The biological activity was considerably reduced: fat cell assay 20%, blood sugar depression 30%.