gebhart/patrepeval huggingface dataset:
Desolvation effects in the esterolysis catalyzed by imidazole-containing polymers (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDesolvation effects in the esterolysis catalyzed by imidazole-containing polymersHiromi Kitano, Zonghua Sun, and Norio IseCite this: Macromolecules 1983, 16, 12, 1823–1827Publication Date (Print):December 1, 1983Publication History Published online1 May 2002Published inissue 1 December 1983https://pubs.acs.org/doi/10.1021/ma00246a005https://doi.org/10.1021/ma00246a005research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Improvement of the Minimum Detectability of Electro-Optic Sampling by Using a Structurally New Probe (1991)

For practical applications, such as the measurement of high speed electrical waveforms at internal nodes in integrated circuits, we proposed, for the first time in 1989 1) , Electro-Optic (E-0) sampling using a longitudinal probe and laser diode (LD) pulses. The longitudinal probe measures electric field just above the conductor and is free from crosstalk problems occurring in transverse probing. The laser diode is compact, inexpensive, reliable and easy to handle. Moreover, the laser pulses can be easily synchronized with the clock signals for the Device Under Test (DUT).
Launch Envelope Optimization of Virtual Sliding Target Guidance Scheme (2009)

This paper presents an optimization of the performance of a recently proposed virtual sliding target (VST) guidance scheme in terms of maximization of its launch envelope for three-dimensional (3-D) engagements. The objective is to obtain the launch envelope of the missile using the VST guidance scheme for different lateral launch angles with respect to the line of sight (LOS) and demonstrate its superiority over kinematics-based guidance laws like proportional navigation (PN). The VST scheme uses PN as its basic guidance scheme and exploits the relation between the atmospheric properties, missile aerodynamic characteristics, and the optimal trajectory of the missile. The missile trajectory is shaped by controlling the instantaneous position and the speed of a virtual target which the missile pursues during the midcourse phase. In the proposed method it is shown that an appropriate value of initial position for the virtual target in 3-D, combined with optimized virtual target parameters, can significantly improve the launch envelope performance. The paper presents the formulation of the optimization problem, obtains the approximate models used to make the optimization problem more tractable, and finally presents the optimized performance of the missile in terms of launch envelope and shows significant improvement over kinematic-based guidance laws. The paper also proposes modification to the basic VST scheme. Some simulations using the full-fledged six degrees-of-freedom (6-DOF) models are also presented to validate the models and technique used.
Carcinosarcoma (Malignant Mixed Mullerian Tumor) of the Uterus With a Rhabdoid Tumor Component:<i>An Immunohistochemical, Ultrastructural, and Immunoelectron Microscopic Case Study</i> (1995)

A case of uterine carcinosarcoma (malignant mixed müllerian tumor) of the uterus containing a rhabdoid tumor element is described. In addition to a malignant glandular component and anaplastic sarcomatous areas, this tumor had multiple foci with histologic and ultrastructural features of malignant rhabdoid tumor. Vimentin positivity by immunohistochemistry was confirmed by immunoelectron microscopy. Although three malignant rhabdoid tumors of the uterus have been previously described, in addition to rhabdoid differentiation in an endometrial stromal sarcoma, to our knowledge this is the first report of rhabdoid tumor differentiation occurring within a uterine carcinosarcoma.
Heterocyclic amines. III. Synthesis of 3,5-diaminopyrazole (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleHeterocyclic amines. III. Synthesis of 3,5-diaminopyrazoleJoseph A. Settepani and Jerry B. StokesCite this: J. Org. Chem. 1968, 33, 6, 2606Publication Date (Print):June 1, 1968Publication History Published online1 May 2002Published inissue 1 June 1968https://pubs.acs.org/doi/10.1021/jo01270a126https://doi.org/10.1021/jo01270a126research-articleACS PublicationsRequest reuse permissionsArticle Views489Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Elucidation of β-Oxidation Pathways in <i>Ralstonia eutropha</i> H16 by Examination of Global Gene Expression (2010)

Ralstonia eutropha H16 is capable of growth and polyhydroxyalkanoate production on plant oils and fatty acids. However, little is known about the triacylglycerol and fatty acid degradation pathways of this bacterium. We compare whole-cell gene expression levels of R. eutropha H16 during growth and polyhydroxyalkanoate production on trioleate and fructose. Trioleate is a triacylglycerol that serves as a model for plant oils. Among the genes of note, two potential fatty acid β-oxidation operons and two putative lipase genes were shown to be upregulated in trioleate cultures. The genes of the glyoxylate bypass also exhibit increased expression during growth on trioleate. We observed that single β-oxidation operon deletion mutants of R. eutropha could grow using palm oil or crude palm kernel oil as the sole carbon source, regardless of which operon was present in the genome, but a double mutant was unable to grow under these conditions. A lipase deletion mutant did not exhibit a growth defect in emulsified oil cultures but did exhibit a phenotype in cultures containing nonemulsified oil. Mutants of the glyoxylate shunt gene for isocitrate lyase were able to grow in the presence of oils, while a malate synthase (aceB) deletion mutant grew more slowly than wild type. Gene expression under polyhydroxyalkanoate storage conditions was also examined. Many findings of this analysis confirm results from previous studies by our group and others. This work represents the first examination of global gene expression involving triacylglycerol and fatty acid catabolism genes in R. eutropha.
Advocacy and nursing: implications for women's health care. (1992)

A recent government report indicates that women in Victoria are dissatisfied with the health care they receive. Advocacy is presented as a core concept which could be utilized by nurses to effect change in women's health care. Some models of advocacy in the nursing literature are examined and related to the aims of the women's health movement. The model of patients' rights advocate appears to have the greatest congruence with the aims of this movement and could be adopted by nurses to improve women's experience of the health care they receive.
Mobile media content sharing in UPnP-based home network environment (2008)

Many modern handheld devices feature functions of taking pictures, shooting video clips, or recording audio sounds. However, such devices are usually equipped with small display panels and poor acoustic equipments. In order to achieve better user experience with high quality panel or audio stereo, users often need to transfer or copy digital media contents to external powerful devices, like personal computers and home theater devices. Nevertheless, it can be awkward or difficult for users to follow up a series of operations of connection setup and media content transfer. In this paper, we present a mobile media content sharing mechanism based the UPnP framework and wireless communication technology in home network environments. As a result, users could conveniently share media contents stored in mobile devices and play them by other home networked player devices. The demonstration result shows that the developed mechanism is attractive and of practicability and ease of use.
Enhancement of the formation of Fe16N2 on Fe films by Co additions (invited) (1994)

Effects of Co additions on the formation of Fe16N2 have been investigated by observing nitrides formed on thin-film surfaces. Thin films of Fe-Co alloys with a (100) surface sputter-deposited on MgO(100) substrates are exposed to a mixed gas of NH3 and H2. The 16:2 nitride was observed to form on a surface of Fe-10 at. % Co film at a nitriding temperature of 500 °C. The formation temperature is 50 °C higher than for pure iron. The amount of the formed 16:2 nitride has been found to be 3× larger for Fe-10 at. % Co than for pure iron.
Long‐term maintenance of functional primary human hepatocytes using small molecules (2019)

The immediate deterioration of primary human hepatocytes (PHHs) during culture limits their utility in drug discovery studies. Here, we report that a cocktail of four small molecule signaling inhibitors, termed YPAC, is useful for maintaining various hepatic functions of PHHs, including albumin and urea productivity, glycogen storage, and cytochrome P450 (CYP) expression. Most importantly, we found that YPAC allows PHHs to retain enzymatic activities of CYP1A2, CYP2B6, and CYP3A4 even after 40 days of culture, and that inducibility of CYP3A4 activity in response to the prototypical inducers rifampicin and phenobarbital is also maintained. Our novel approach could facilitate drug discovery studies.
Decreased CSF Concentrations of Homovanillic Acid and γ-Aminobutyric Acid in Alzheimer's Disease (1982)

Fifteen patients, 48 to 72 years old, with Alzheimer's disease were studied. Clinical status was assessed by neurologic and neuropsychologic examinations and psychometric testing. Patients were divided into two groups on the basis of clinical assessment: group 1, little mental deterioration, and group 2, serious mental deterioration. Nineteen subjects, 27 to 72 years old, without neurologic disease served as controls. Levels of homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and gamma-aminobutyric acid (GABA) were determined in lumbar CSF by fluorimetric or radioreceptor binding (GABA) methods. The HVA concentrations increased with age in the controls, whereas the GABA levels decreased with age and 5-HIAA levels were not modified. When compared with the age-matched controls, the patients with Alzheimer's disease showed low concentrations of HVA but not of 5-HIAA or GABA. The decrease in HVA level was more pronounced in patients with severe mental deterioration and therefore appeared to be disease related.
Surface wave operation mode of the slot antenna microwave plasma source SLAN (1996)

A new slot antenna concept allows the generation of large volume 2.45 GHz discharges. The microwave power is coupled from an annular waveguide (ring cavity) through ten equidistantly positioned resonant coupling slots into the quartz plasma chamber. Langmuir double probe axial distribution measurements of the electron density and temperature are performed for argon, helium and nitrogen discharges in a power range from 120 to 1200 W and a pressure range from 10 to 150 Pa. Characteristic differences in the discharge behavior for the various gases are presented. With argon a surface wave at the plasma-quartz interface can be excited, already at 200 W. The resulting plasma column can extend up to 450 mm in length along the tube with 160 mm diameter. The surface wave mode is identified as a m=5 mode by visual inspection of the plasma formation and by recording the azimuthal electric field distribution. In contrast to argon, for helium and nitrogen no surface wave generation for power levels up to 1200 W are observed. Within the investigated power range both gases show a diffusion controlled variation of the electron density. This is verified by fitting the axial density data to the time-independent diffusion equation for helium and nitrogen and to a simplified surface wave model for argon.
Evaluation of Jejunal Function in Wolmanʼs Disease (1991)

Findings in a 1-month-old male infant with Wolman's disease, a rare autosomal defect characterized by intractable diarrhea and severe malabsorption, are described. Investigations in this case focused on the digestive and absorptive functions of the jejunum using histological, biochemical, and electrophysiological methods. The intestinal villi were found to be distorted and club-shaped as a result of the infiltration of foam cells into the lamina propria of the mucosa. The microvilli of the epithelial cells were found on electron microscopy to be markedly shortened and irregular, and had a severe impairment of disaccharidase activity. Documentation of the loss of the sugar- and amino acid-evoked potential differences in the jejunum confirmed the severity of intestinal malabsorption. These observations indicate that the intestinal damage in Wolman's disease is so severe as virtually to exclude the absorption of any form of enteral nutrition. Despite the administration of i.v. hyperalimentation, the infant died of hepatic failure at the age of 6 months.
Enhanced antigen detection in immunohistochemical staining using a ‘digitized’ chimeric antibody (2015)

The immunohistochemical (IHC) staining of mouse tissue sections using antibodies of mouse origin can result in high nonspecific background due to the staining of endogenous immunoglobulins (Igs) by enzyme-conjugated secondary antibodies. In order to obviate this issue, we developed a chimeric mouse-human anti-p53 monoclonal antibody (MH242) by grafting the variable regions of a known mouse antibody into a human Ig scaffold. This facilitated use of an anti-human secondary antibody, and resulted in near-zero background when compared with its parental mouse monoclonal antibody (PAb242). Furthermore, the chimeric antibody enabled reproducible detection of mutant p53 (homozygous R172H) expression in mouse tissue, an observation hitherto largely equivocal based on the use of existing antibodies. The approach we describe leads to the generation of tractable antibody reagents, whose integrity can be readily verified through DNA sequencing of expressor plasmids. The wide-spread adoption of such 'digitized' antibodies should reduce experimental disparities that can commonly arise through variations in antibody quality.
Load following functions using distributed energy resources (2002)

Technology improvements in fuel cells, microturbines and energy storage devices have provided the opportunity for dispersed energy resources at the distribution level. At the same time, deregulation has begun to allow for the provision of various ancillary services, such as, load following. This paper investigates some possible approaches to load following, at the distribution level. An algorithm is proposed for the fast three phase load flow calculations needed to simulate the slow dynamics of load following. We simulate a typical distribution system where several distributed energy resources have been added. Using simplified dynamics for the sources and loads, strategies to provide load following without increased unbalance are suggested. We identify modeling improvements that are needed to fully investigate these algorithms.
Bernstein and the Middle Class (2002)

Abstract This paper explores Basil Bernstein's insights into education and social class, and in particular the relevance of his work for understanding the British middle class. Bernstein is one of the few sociologists of education to recognise and explore differences and tensions within the middle class. We begin by exploring some of the influences of Bernstein's theorisation of social class in general, and outline his main ideas on the relationship between the middle class and education in particular. We then examine the relevance of his work for research on education and middle-class differentiation through drawing on data from our 'Destined for Success' project. This project traced the educational biographies of 300 young men and women from the beginning of their promising educational secondary school career to their mid-twenties. We argue that the distinctive dispositions and orientations of the 'new' and 'old' middle class proposed by Bernstein are evident within parental preferences for types of school, processes of student engagement and, ultimately, differentiated middle-class identities.
Contact resistance of dibenzotetrathiafulvalene-based organic transistors with metal and organic electrodes (2008)

Thin-film transistors of dibenzotetrathiafulvalene (DBTTF) are investigated by changing the source and drain (S/D) electrode materials. Not only the mobility but also the contact resistance, estimated from the transfer line method, changes depending on the metal work functions. Nonetheless, S/D electrodes made of a metallic organic charge-transfer salt, (tetrathiafulvalene) (tetracyanoquinodimethane) [(TTF)(TCNQ)] exhibits much smaller contact resistance, which is attributed to small potential shift on the organic/organic interface compared with the organic/metal interface. A thin film of (DBTTF)(TCNQ) works as an active layer of air-stable n-channel organic transistors when (TTF)(TCNQ) is used as the S/D electrodes.
Three papers in neuroeconomics (2007)

I consider the role of automatic psychological and neural processes in different settings. First, how does advertising affect consumer perceptions of a product? I assert that one of the ma jor mechanisms used in marketing is the creation of implicit associations among concepts. A neural network framework is adapted to model how these associations evolve and interact. Use of this formal model allows us to consider some of the indirect effects of advertising, particularly “spillover” and “dilution” effects where the advertisements for one product can help or harm ther perceptions of another. Second, I use fMRI to consider neural activation patterns during strategic thinking. Two studies reveal the possible importance of various neural areas to belief formation, strategic deception, and suspicion. The ﬁrst study focuses on the neural correlates of belief formation, particularly the difference between equilibrium and out-of-equilibrium decisions. We ﬁnd both neural activations and behavioral evidence that sub jects have relatively shallow belief processes, often apparently assigning too much agency to themselves, when they are out of equilibrium. The second study focuses on a bargaining interaction where a “buyer” has incentive to deceive a “seller” in order to get a low price for a hypothetical product. We ﬁnd neural correlates to strategic deception in the dorsal striatum and to suspicion of deception in the ACC.
HNF1, a homeoprotein member of the hepatic transcription regulatory network (1992)

Numerous liver specific genes are transcriptionally activated by the binding to their promoter or enhancer of Hepatic Nuclear Factor 1 (HNF1). HNF1 contains a variant homeo-domain and binds to DNA as either a homodimer or a heterodimer with the vHNF1 protein. Surprisingly, HNF1 is not restricted to hepatocytes but is expressed in epithelial cells of several endoderm derived organs and in mesoderm derived kidney tubules. Hence, HNF1 alone can not account for the differentiated state of the hepatic cells. In fact, several other liver-enriched transcription factors have been cloned. The hepatic phenotype could result from the combinatorial expression of these regulators. Possible involvement of these trans-acting factors in liver organogenesis and hepatic differentiation is discussed.
Mesenchymal Stem Cells Use Integrin β1 Not CXC Chemokine Receptor 4 for Myocardial Migration and Engraftment (2007)

Recent evidence has demonstrated the importance of bone marrow-derived mesenchymal stem cells (BM-MSCs) in the repair of damaged myocardium. The molecular mechanisms of engraftment and migration of BM-MSCs in the ischemic myocardium are unknown. In this study, we developed a functional genomics approach toward the identification of mediators of engraftment and migration of BM-MSCs within the ischemic myocardium. Our strategy involves microarray profiling (>22,000 probes) of ischemic hearts, complemented by reverse transcription-polymerase chain reaction and fluorescence-activated cell sorting of corresponding adhesion molecule and cytokine receptors in BM-MSCs to focus on the coexpressed pairs only. Our data revealed nine complementary adhesion molecules and cytokine receptors, including integrin beta1, integrin alpha4, and CXC chemokine receptor 4 (CXCR4). To examine their functional contributions, we first blocked selectively these receptors by preincubation of BM-MSCs with specific neutralizing antibodies, and then we administered these cells intramyocardially. A significant reduction in the total number of BM-MSC in the infarcted myocardium was observed after integrin beta1 blockade but not integrin alpha4 or CXCR4 blockade. The latter observation is distinctively different from that reported for hematopoietic stem cells (HSCs). Thus, our data show that BM-MSCs use a different pathway from HSCs for intramyocardial trafficking and engraftment.