gebhart/patrepeval huggingface dataset:
The effect of BaM/PANI composition with epoxy paint matrix on single and double layers coating with spray coating method for radar absorbing materials applications (2018)

In this study, RAM composite has been succesfully synthesized by mixing BaM as magnetic materials and PANI as conductive materials. BaM and PANI materials were prepared separately by solid state method and polymerization method, respectively. To investigated the presence of BaM phase and magnetic property of the as prepared BaM, XRD pert PAN analytical and VSM 250 Dexing Magnet were employed. Inductance Capacitance Resistance technique was carried out to measure electrical conductivity of the synthesized PANI materials. In order to further characterized the structural features of BaM and PANI, SEM-EDX FEI 850 and FTIR characterizations were conducted. RAM composite was prepared by mixing BaM and PANI powders with ultrasonic cleaner. Afterwards, VNA (Vector Network Analyzer) characterization was carried out to determine reflection loss value of RAM by applying mixed RAM composite and epoxy paint on aluminum plate using spray gun. Microscopic characterization was employed to investigated the distribution of RAM particles on the substrate. It was found that reflection loss value as low as -27.153 dB was achieved when applied 15 wt% BaM/PANi composite at 100.6 µm thickness. In addition, the absorption of electromagnetic waves value increase as the addition of RAM composite composition increases.
Inflow Control Device and Near-Wellbore Interaction (2008)

Abstract The optimization of inflow performance in long horizontal open hole completions involves several challenges. One is the formation damage and well clean-up. Another is the heel – toe effect caused by flow friction in the pipe, resulting in risk of gas or water coning in the heel and limited drainage from the toe. Due to such effects, horizontal wells may suffer from reduced PI and reserves left behind. The introduction of Inflow Control Device (ICD) technology has proved to significantly increase the recoverable reserves from many fields. The ICD provides a controlled pressure drop which is a function of the flow rate. This restricts high producing zones and thus stimulates low producing zones, resulting in: Improved well clean-up reducing the effect of formation damage caused by the drilling of the well. Equalizing the flux along the well path, giving reduced coning effects. Reduced annular flow. This reduces the risk of sand production behind the screen and subsequent plugging or erosion. This paper is discussing how an ICD interacts with the reservoir and near well bore region. The first step is the dynamic of the clean-up process. The optimal differential pressure can now be applied to remove near well bore damage. A model illustrating the propagation of this process will be described. This will be correlated with experimental results from clean-up of core plugs and practical field experience. The purpose of this work is to illustrate how the use of the ICD technology both improves the well PI and increases the recoverable reserves.
Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap (2005)

Recent findings support a model for neocortical area formation in which neocortical progenitor cells become patterned by extracellular signals to generate a protomap of progenitor cell areas that in turn generate area-specific neurons. The protomap is thought to be underpinned by spatial differences in progenitor cell identity that are reflected at the transcriptional level. We systematically investigated the nature and composition of the protomap by genomic analyses of spatial and temporal neocortical progenitor cell gene expression. We did not find gene expression evidence for progenitor cell organisation into domains or compartments, instead finding rostrocaudal gradients of gene expression across the entire neocortex. Given the role of Fgf signalling in rostrocaudal neocortical patterning, we carried out an in vivo global analysis of cortical gene expression in Fgfr1 mutant mice, identifying consistent alterations in the expression of candidate protomap elements. One such gene, Mest, was predicted by those studies to be a direct target of Fgf8 signalling and to be involved in setting up, rather than implementing, the progenitor cell protomap. In support of this, we confirmed Mest as a direct transcriptional target of Fgf8-regulated signalling in vitro. Functional studies demonstrated that this gene has a role in establishing patterned gene expression in the developing neocortex, potentially by acting as a negative regulator of the Fgf8-controlled patterning system.
The crystal structure of tegafur (.BETA.-form): Comparison with .ALPHA.-form. (1986)

The crystal structure of the second polymorphic form of the title compound (α-form : Chem. Pharm. Bull., 30, 2629 (1982)) has been determined by X-ray diffraction analysis of a single crystal. The crystal of the β-form, C8H9FN2O3, is monoclinic, space group P21/n, with a=11.891 (5), b=14.556 (2), c=5.062 (1)Å, β=99.05 (2)°, U=865.3 (4)Å3, Mr=200.17, Z=4; Dc=1.54, Dm=1.54 gcm-3, F(000)=416, λ(Mo Kα)=0.7107Å, μ=1.433 cm-1. The structure was solved by the direct method using the MULTAN 78 program. Refinement by the full-matrix least-squares method gave a final R factor of 0.055 (1669 independent reflections). Bond lengths and angles agree well with those of both molecules in the α-form. The molecular conformation is very similar to one of those in the α-form. The cyclic dimer structure of the β-form is different from that of the α-form.
Increasing effective link bandwidth by suppressing replicated data (1998)

In the Internet today, transfer rates are often limited by the bandwidth of a bottleneck link rather than the computing power available at the ends of the links. To address this problem, we have utilized inexpensive commodity hardware to design a novel link layer caching and compression scheme that reduces bandwidth consumption. Our scheme is motivated by the prevalence of repeated transfers of the same information, as may occur due to HTTP, FTP, and DNS traffic. Unlike existing link compression schemes, it is able to detect and use the long-range correlation of repeated transfers. It also complements application level systems that reduce bandwidth usage, e.g., Web caches, by providing additional protection at a lower level, as well as an alternative in situations where application-level cache deployment is not practical or economic. We make three contributions in this paper. First, to motivate our scheme we show by packet trace analysis that there is significant replication of data at the pack...
Importance of the propeptide sequence of human preproparathyroid hormone for signal sequence function. (1988)

The function of amino-terminal pro-specific peptides (propeptides), sequences often found on intermediate precursor forms of secreted proteins, is poorly understood. Human preproparathyroid hormone (prepro-PTH), a precursor protein containing such a propeptide, is initially synthesized as a precursor containing a 25-amino acid signal sequence, a 6-amino acid propeptide, and the 84-amino acid mature secreted peptide. Cloned cDNA encoding prepro-PTH and synthetic oligonucleotides were used to generate a mutant missing precisely the pro-specific sequences. The effects of this deletion on signal sequence function and on secretion per se were assessed after expression of the mutant cDNA in intact cells and in a cell-free translation system using synthetic mRNA in the presence of microsomal membranes. The mutant precursor protein was inefficiently translocated and cleaved, and cleavage occurred both at the normal site and within the signal sequence. Thus, for the eukaryotic protein prepro-PTH, sequences immediately downstream and separate from the classically defined signal sequence facilitate accurate and efficient signal function.
Empowered by wireless communication (2010)

In recent years, tremendous progress has been made in understanding the dynamics of vehicle traffic flow and traffic congestion by interpreting traffic as a multiparticle system. This helps to explain the onset and persistence of many undesired phenomena, for example, traffic jams. It also reflects the apparent helplessness of drivers in traffic, who feel like passive particles that are pushed around by exterior forces; one of the crucial aspects is the inability to communicate and coordinate with other traffic participants. We present distributed methods for solving these fundamental problems, employing modern wireless, ad-hoc, multi-hop networks. The underlying idea is to use these capabilities as the basis for self-organizing methods for coordinating data collection and processing, recognizing traffic phenomena, and changing their structure by coordinated behavior. The overall objective is a multi-level approach that reaches from protocols for local wireless communication, data dissemination, pattern recognition, over hierarchical structuring and coordinated behavior, all the way to large-scale traffic regulation. In this article, we describe three types of results: (i) self-organizing and distributed methods for maintaining and collecting data (using our concept of Hovering Data Clouds ); (ii) adaptive data dissemination for traffic information systems; (iii) methods for self-recognition of traffic jams. We conclude by describing higher-level aspects of our work.
hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells (2008)

Telomerase is proposed as an anticancer target. Increasing evidence suggests that telomerase is involved in functions independent of telomere-extension activity. In this study, we designed a small interfering RNA (siRNA) targeting human telomerase reverse transcriptase (hTERT), the catalytic subunit of telomerase. Using transient and persistent transfection of hTERT siRNA into telomerase-positive human colon carcinoma HCT116 cells, we demonstrated that hTERT siRNA suppresses hTERT expression and leads to inhibition of telomerase activity and HCT116 cell growth and in vivo tumorigenicity in nude mice. Further analysis indicated that depletion of hTERT reduces cell adhesion, migration, and invasion prior to inhibition of cell proliferation. Downregulation of hTERT also decreased the expression levels of adhesion- and motility-related proteins, in particular c-Met and integrins. The lack of detectable changes in telomere length showed that downregulation of hTERT in the present system had no significant effect on telomere-extension activity. Taken together, our results highlight the therapeutic potential of a novel hTERT siRNA and suggest that hTERT is involved in the regulation of cell motility in a telomere-independent manner.
A Self-Test to Detect a Heart Attack Using a Mobile Phone and Wearable Sensors (2008)

This paper describes a heart attack self-test application for a mobile phone that allows potential victims, without the intervention of a medical specialist, to quickly assess whether they are having a heart attack. Heart attacks can occur anytime and anywhere. Using pervasive technology such as a mobile phone and a small wearable ECG sensor it is possible to collect the user's symptoms and to detect the onset of a heart attack by analysing the ECG recordings. If the application assesses that the user is at risk, it will urge the user to call the emergency services immediately. If the user has a cardiac arrest the application will automatically determine the current location of the user and alert the ambulance services and others to the person's location.
On-farm seed priming to accelerate germination in rainfed, dry-seeded rice (1997)

This article 'On-farm seed priming to accelerate germination in rainfed, dry-seeded rice' appeared in the International Rice Research Notes series, created by the International Rice Research Institute (IRRI) to expedite communication among scientists concerned with the development of improved technology for rice and rice-based systems. The series is a mechanism to help scientists keep each other informed of current rice research findings. The concise scientific notes are meant to encourage rice scientists to communicate with one another to obtain details on the research reported.
Super ray based updates for occupancy maps (2016)

We present a novel approach, Super Ray, for efficiently updating map representations such as grids and octrees with point clouds. In this paper, we define a super ray for points as a representative ray to them with an associated frustum. A super ray is constructed in a way that updating those points has the same set of cells accessed during the map update process. As a result, we can perform the update process with a super ray in a single traversal on the map, resulting in performance improvement without compromising any representation accuracy of the map. For constructing super rays efficiently, we propose mapping lines for handling 2-D and 3-D cases from an observation that edges or grid points branch out the access pattern of updating the map. Our method is general enough to be applied for variety of occupancy map structures based on axis-aligned space subdivisions such as grids and octrees. We test our method into indoor and outdoor benchmarks, and achieve 2.5 times on average (up to 3.5 times) performance improvement over the state-of-the-art update method for OctoMap and grid maps.
Interferometric noncontact on-line dosimetry control during selective retina treatment (SRT) (2005)

In selective retina treatment (SRT) spatial confined tissue damage in the absorbing retinal pigment epithelium (RPE) is obtained by applying microsecond laser pulses. The damage in the RPE is caused by transient microbubbles forming around laser heated melanin granules inside the cells. For treatment of RPE related diseases, SRT is thought to share the therapeutic benefits of conventional photocoagulation but without affecting the photoreceptors. A drawback for effective clinical SRT is that the laser-induced lesions are ophthalmoscopically invisible. Therefore, a real-time feedback system for dosimetry is demanded in order to avoid undertreatment or unwanted collateral damage to the adjacent tissue, which is observed at about twofold threshold radiant exposure for RPE damage. We demonstrate that interferometry is capable of detecting microbubbles at threshold irradiation for RPE damage. A porcine ex-vivo RPE model, which was irradiated by a Nd:YLF laser (350ns/1700ns@527nm), was employed. The irradiated area was simultaneously probed by a Michelson interferometer. Cell viability assays were performed after irradiation. Cell damage was compared to the interferometric data. At threshold for cell damage a change in the interferometric transients was observed due to microbubble formation. Thus, interferometry could serve as a non-contact real-time dosimetry control during selective targeting of the RPE in vivo. From the time resolved motion of the bubble interface, which is determined by interferometry, the maximum bubble size is obtained. This gives an estimation for the damage range in the tissue. Knowledge of the damage range as a function of the irradiation parameters is helpful in optimizing SRT.
Signature Analysis (1995)

A signature analyser is a specialised item of test equipment that converts a complex sequential bit pattern at a circuit node into a hexadecimal ‘signature’ that is displayed on a segment display unit. This signature can be compared with a reference signature for the circuit node in order to help to identify circuit faults. The signature analyser is particularly useful for computer circuit testing. If a specific test program is run for a specific computer hardware configuration, then a repeatable set of signatures will be produced at different points in the circuit.
T cell-derived glucosteroid response-modifying factor (GRMFT): a unique lymphokine made by normal T lymphocytes and a T cell hybridoma. (1984)

Mouse spleen cells and a murine T cell hybridoma, FS6 14.13.1, produce a glucosteroid response-modifying factor (GRMFT) after stimulation with concanavalin A. GRMFT blocks glucosteroid suppression of helper T cell function and the growth of granulocyte/macrophage progenitor cells in vitro. IL 1 also protects helper T cells and myeloid precursors from glucosteroid suppression. This suggests that GRMFT and IL 1 act congruently to ensure that an effective immune response is generated when endogenous glucosteroid levels are elevated. To understand the role of GRMFT in normal immune responses and in disease states characterized by imbalances in the immune system, we began to purify and characterize GRMFT. GRMFT appears to be distinct from other well-characterized T cell-derived factors. GRMFT is larger than IL 2 as determined by gel exclusion chromatography and is completely separated from IL 2 by isoelectric focusing. Furthermore, purified IL 2 does not have GRMFT activity. Purified IL 3 also lacks GRMFT activity, and conditions that inactivate immune interferon have no effect on GRMFT. Thus, GRMFT is different from IL 2, IL 3, and immune interferon. GRMFT also lacks activity in the thymocyte co-mitogenic assay and is therefore different from IL 1. Finally, FS6 14.13.1 reportedly does not produce TRF or CSF, which suggests that GRMFT is different from these molecules as well.
OBSERVATIONS ON THE EFFECTS OF INSULIN INTRODUCED INTO THE MEDIUM OF TISSUE CULTURES (1924)

A summary of the effects on the growth of tissue in vitro noted when insulin had been added to the culture medium is presented because of its potential value in this line of investigation. Dr. Thalhimer suggested the addition of insulin as a possible means to augment the growth of tissue and to disclose the nature of its action. Chick fibroblasts were cultivated from 9 to 10 day old embryos, the Carrel flask method being used. The medium contained glucose in percentages from 0.1 to2.5. Two sets of cultures were maintained. To one set, from 1 to 2 per cent. of insulin was added; to the second, otherwise identical, no insulin was added. The sugar content was determined in duplicate cultures by the Folin-Wu method, and the H-ion concentration was estimated by the drop calorimetric procedure. The perimeter of the growth was compared by using the planimeter method of Carrel
Inhibition of Development of <i>N, N′</i>‐Dimethylhydrazine‐induced Rat Colonic Aberrant Crypt Foci by Pre, Post and Simultaneous Treatments with 24<i>R</i>,25‐Dihydroxyvitamin D<sub>3</sub> (1997)

It has recently been reported that new vitamin D3 derivatives can exert inhibitory effects on colon carcinogenesis in rats. In the present study the chemopreventive potential of 24R,25-dihydroxyvitamin D3 (24R,25(OH)2vitamin D3) was assessed in a murine model of colon carcinogenesis. In experiment 1, male 6-week-old F344 rats were administered N,N'-dimethylhydrazine (DMH) 20 mg/kg s.c. once a week 4 times. The rats were fed 24R,25(OH)2vitamin D3 at 10 ppm in the diet prior to (pre), together with (simultaneous) or after (post) DMH treatment. Modifying effects were assessed using aberrant crypt foci (ACF), putative preneoplastic lesions, as the end point markers in this model of colon carcinogenesis. After 8 weeks, pre and more markedly simultaneous administration of 24R,25(OH)2vitamin D3 was found to have reduced the total numbers of ACF and significantly inhibited the development of foci. After 16 weeks, numbers of foci with > or = 4 crypts, which are more likely to progress to tumors, were significantly reduced. The most pronounced inhibition of ACF development was noted in rats fed the 24R,25(OH)2vitamin D3 after DMH administration. The reduction was particularly marked in the proximal colon. Blood levels of calcium were not significantly increased over the control levels in groups administered DMH and the vitamin. Immunohistochemical staining showed numbers of proliferating cell nuclear antigen-positive cells to be lower in the colonic epithelia of rats fed the vitamin D3 metabolite than in the controls. In experiment 2, the effect of 24R,25(OH)2vitamin D3 on the alterations in c-fos, c-myc and c-jun oncogene expression in response to DMH administration was examined by northern blot analysis. The early increase in expression of ornithine decarboxylase (ODC) activity was not altered by 24R,25(OH)2vitamin D3. The results suggest that 24R,25(OH)2vitamin D3 is a cancer chemopreventive agent which may suppresses DMH induction of lesions and their subsequent development via an antiproliferative action.
Association of tumor washout rates and accumulation of technetium-99m-MIBI with expression of P-glycoprotein in lung cancer. (1998)

The current data strongly suggest that, although the reduced ability for the tumors to accumulate MIBI correlates well with the increased levels of Pgp expression, tumor washout rates of MIBI do not correlate with the density of Pgp in tumor tissues. Our results also warrant additional research for correlating immunohistological and imaging findings with messenger RNA levels determined by polymerase chain reaction and flow cytometry.
Brief Report: M‐Ficolin Levels Reflect Disease Activity and Predict Remission in Early Rheumatoid Arthritis (2013)

In patients with early RA, elevated plasma M-ficolin levels correlated with a high DAS28 and a high HAQ score at baseline and 1 year. A low M-ficolin level was the strongest predictor of remission and low disease activity in a multivariate analysis.
L'imagerie échographique ultrarapide et son application à l'étude de la viscoelasticité du corps humain (2004)

Augmenter la cadence d'image des échographes est un des enjeux majeurs de l'imagerie ultrasonore. Il y a, en effet, avec l'avènement de l'échographie tridimensionnelle, un réel besoin d'accélérer l'acquisition des signaux ultrasonores tout en gardant une très bonne qualité d'image. Les échographes à haute cadence pourraient également imager des mouvements tissulaires très rapides, aujourd'hui indétectables, et offrir de nouvelles perspectives au diagnostic médical.En se basant sur un échographe complètement programmable développé au laboratoire Ondes et Acoustique, ce travail de thèse explore les potentialités d'une imagerie ultrarapide et en particulier son application à l'étude des propriétés viscoélastiques des tissus biologiques.Dans une première partie, nous explorons les méthodes pour parvenir à une imagerie ultrarapide (200 à 10000 Hz) et leurs conséquences sur la qualité de l'image échographique. Ces cadences sont ensuite utilisées pour imager la propagation d'ondes de cisaillement impulsionnelles dans les tissus mous. Sensibles aux propriétés viscoélastiques des tissus, ces ondes peuvent être d'un grand intérêt pour la détection et le diagnostic de pathologies telles que le cancer du sein. La génération de ces ondes dans le corps est faite à distance par une source mécanique mobile crée par force de radiation et se déplaçant à une vitesse supersonique. Cette nouvelle technique de diagnostic, baptisée "Supersonic Shear Imaging" a été validé in vitro et in vivo. Elle devrait fournir au médecin une cartographie quantitative des paramètres élastiques et visqueux du corps humain.
New Fluid Amplifier Techniques for Speed Controls (1965)

<div class="htmlview paragraph">Fluid amplifiers are now receiving considerable attention by control engineers due to their potential for high reliability, ruggedness, and fast response. For applications such as speed controls for jet engines, steam turbines and other prime movers, fluid amplifier systems are now being studied that use both digital and analog techniques. This paper describes several approaches to shaft speed control that differ from the above techniques in that fluid circuits analogous to A. C. carrier systems are used. Results of testing are presented for three specific “a-c” fluid amplifier circuits.</div>