gebhart/patrepeval huggingface dataset:
Liquid chromatographic methods for vitamins A and D in multivitamin-mineral formulations. (1989)

Liquid chromatographic screening procedures have been developed for the estimation of vitamins A and D in multivitamin-mineral tablet, capsule, gelatin capsule, and syrup formulations. The procedure can be used for measuring vitamin A present as either retinyl acetate or retinyl palmitate, and also for measuring the contribution to total vitamin A activity from 13-cis retinyl esters. The retinyl esters and their isomers are resolved from each other and their oxidation products. Ergocalciferol and cholecalciferol are not resolved from each other but they are resolved from other vitamin D isomers and from vitamins A, E, and K and their degradation products. Both assays use a 3 microns amino column, with a mobile phase of hexane for vitamin A and 1% isopropanol in hexane for vitamin D. The precision of replicate injections for vitamins A and D is better than 1% and the recovery from spiked syrups is better than 98%. The coefficient of variation for both assay methods is about 5%. Twenty formulations were analyzed for vitamin A and 24 were analyzed for vitamin D.
Glass Bead Probes of Local Structural and Mechanical Properties of Fluid, Supported Membranes (2006)

Probing membranes: Nonspecific interactions between glass beads and supported lipid membranes act as a simple tool to characterize their local structure and mechanical properties. The beads differentiate monolayers (see figure B) from fluid bilayers (A) by inducing a qualitatively different elastic response, characterized by undeformed binding for monolayers and membrane wrapping for bilayers. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2267/2006/z600222_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Field-Development Case Study: Production Optimization Through Continuous Multidisciplinary Reservoir and Production Monitoring (2008)

Summary This paper presents a field-development case study of a low-permeability turbidite reservoir in Russia. The giant Priobskoye field contains 30°API crude in laminated sandstones of 0.1 to 20 md at a depth of approximately 2,500 m. The complex geology, lack of reservoir information and lack of technology availability caused a 20-year gap between discovery and development. The initial pilot development was halted after poor drilling success, thus the operator invested in 3D-seismic acquisition and an integrated, multidisciplinary reservoir modeling and simulation effort. The subsequent development was based on oriented water-flooding patterns and massive hydraulic fracturing, together with an artificial-lift system equipped with permanent pressure and rate monitoring for evaluation and real-time production enhancement. The optimization of operational practices and introduction of fit-for-purpose technologies enabled a production increase from an intermittent hundreds of BOPD to more than 75,000 BOPD in a period of 3.5 years. The exploitation strategy of this pilot area demonstrated commercially sustainable production from the reservoir and will form the basis for full field development.
[Combined orthodontic and surgical approach to dentofacial abnormalities--coordination of orthodontic and orthognathic therapy. 1]. (1991)

Correction of dentofacial deformities requires a high standard of teamwork between the orthodontist, the oral surgeon and the general dentist. Both, orthodontist and maxillofacial surgeon must establish a combined treatment plan and a time schedule. The treatment goal of presurgical orthodontic preparation includes three-dimensional intra-arch alignment to provide ideal conditions for orthognathic surgery. A typical case report is presented.
Trends in internet of things platforms (2015)

With billions of IOT devices predicted to appear over the next few years, some things have to change.
β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure (2014)

Autoreactive CD8 T cells play a central role in the destruction of pancreatic islet β-cells that leads to type 1 diabetes, yet the key features of this immune-mediated process remain poorly defined. In this study, we combined high-definition polychromatic flow cytometry with ultrasensitive peptide-human leukocyte antigen class I tetramer staining to quantify and characterize β-cell-specific CD8 T cell populations in patients with recent-onset type 1 diabetes and healthy control subjects. Remarkably, we found that β-cell-specific CD8 T cell frequencies in peripheral blood were similar between subject groups. In contrast to healthy control subjects, however, patients with newly diagnosed type 1 diabetes displayed hallmarks of antigen-driven expansion uniquely within the β-cell-specific CD8 T cell compartment. Molecular analysis of selected β-cell-specific CD8 T cell populations further revealed highly skewed oligoclonal T cell receptor repertoires comprising exclusively private clonotypes. Collectively, these data identify novel and distinctive features of disease-relevant CD8 T cells that inform the immunopathogenesis of type 1 diabetes.
Framework for integrating sorcer with rpc-style web services (2005)

Ever since the introduction of Web Services, it has become one of software industry’s most used buzzwords. Web services, in the general meaning of the term, are services offered by one application to other applications via the World Wide Web. An RPC-based Web service is a collection of procedures that can be called by a remote client over the Internet. The integration of WebServices into existing environments is becoming more and more important. The SORCER environment provides the means to create interactive service-oriented programs and execute them without writing a line of source code where jobs and tasks are created using web-based user interfaces. SORCER is service oriented but is object based where as WebServices are protocol based. \n\nThis thesis presents a comprehensive technical overview of RPC Style WebServices and the integration framework that allows Protocol-based RPC Web Services and Object-oriented SORCER service providers to coexist and complement each other in the same environment. My main emphasis would be to develop a framework with generic gateway that would allow SORCER Services to be accessed both as RPC WebServices for web clients and as SORCER Service Providers for SORCER Service requestors
Thermoresponsive Heparin Bioconjugate as Novel Aqueous Antithrombogenic Coating Material (2011)

A novel thermoresponsive aqueous antithrombogenic coating material comprising a heparin bioconjugate with a six-branched, star-shaped poly(2-(dimethylaminoethyl)methacrylate) (6B-PDMAEMA), which has both thermoresponsive and cationic characters, was developed to reduce the thrombogenic potential of blood-contacting materials such as synthetic polymers or tissue-engineered tissues in cardiovascular devices. 6B-PDMAEMA with M(n) of ca. 24 kDa was designed as a prototype compound by initiator-transfer agent-terminator (iniferter)-based living radical photopolymerization from hexakis(N,N-diethyldithiocarbamylmethyl)benzene. Bioconjugation of heparin with 6B-PDMAEMA occurred as soon as both aqueous solutions were simply mixed to form particles. The particle size at 25 °C was less than several hundred nanometers in diameter under a heparin/6B-PDMAEMA mixing weight ratio of over 2.5. The particles were very stable because of the prevention of hydrolysis of 6B-PDMAEMA in its bioconjugated form. Because the lower critical solution temperature of the bioconjugate ranges from approximately 20 to 36 °C for the formation of microparticles, the coating could be done in an aqueous solution at low temperatures. The excellent adsorptivity and high durability of the coating above 37 °C was demonstrated on silicone and polyethylene films by surface chemical compositional analysis. Blood coagulation was significantly reduced on the bioconjugate-coated surfaces. Therefore, the thermoresponsive bioconjugate developed here appears to satisfy the initial requirements for a biocompatible aqueous coating material.
Desalination of Sea Water Using Solar Radiation under Retarded Evaporation Conditions (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDesalination of Sea Water Using Solar Radiation under Retarded Evaporation ConditionsNarendra J. Sheth, Ralph E. Peck, and Darsh T. WasanCite this: Ind. Eng. Chem. Process Des. Dev. 1975, 14, 4, 351–358Publication Date (Print):October 1, 1975Publication History Published online1 May 2002Published inissue 1 October 1975https://doi.org/10.1021/i260056a001RIGHTS & PERMISSIONSArticle Views186Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (877 KB) Get e-Alerts
DNA Fragment Length Polymorphism Analysis of Mycobacterium tuberculosis Isolates by Arbitrarily Primed Polymerase Chain Reaction (1993)

Strain identification of Mycobacterium tuberculosis would prove whether transmission had occurred between individuals. A method to characterize strains of M. tuberculosis has been developed utilizing polymerase chain reaction (PCR). Purified chromosomal DNA of cultured clinical samples of M. tuberculosis were subjected to PCR using short (10-12 nucleotide) oligonucleotide primers. PCR products visualized after agarose gel electrophoresis and ethidium bromide staining demonstrated that different strains of M. tuberculosis give different banding patterns. This technique was used to confirm the relationship between cases of tuberculosis in several clusters, prove the lack of relationship between 2 isolates with the same antibiotic-resistance pattern, confirm a suspected mislabeling event, and suggest the source of infection in a case of tuberculous meningitis. This method is rapid and simple and does not require radioactive probes.
A Multi-sensor Image Fusion and Enhancement System for Assisting Drivers in Poor Lighting Conditions (2006)

A system of multisensor image fusion and enhancement for visibility improvement is proposed in this paper for helping drivers driving at night or under bad weather conditions. Video stream captured by a CCD camera is enhanced, then aligned and fused with another stream captured by a thermal camera to improve the visibility of roads in extremely low lighting conditions. A nonlinear image enhancement technique capable of dynamic range compression and contrast enhancement is developed to enhance the visible images prior to fusion. The thermal image and the enhanced visible image are then aligned based on prior information obtained on image registration process. Pixel-level multiresolution based image fusion method is applied to merge source images. After image fusion, a color restoration is performed on fused images with the chromatic information of visible images. The entire image processing and analysis system is being installed in an FPGA environment. Preliminary results obtained in various experiments conducted with the proposed system are encouraging
Orientation of Nano-Grains in Hard-Disk Media on Ion-Beam Textured Substrates (2007)

The preferred crystal orientations in nano-grains of multilayered magnetic recording media were studied in detail with X-ray diffraction. No in-plane orientation was observed in the media on a flat substrate, while grooved substrates made by ion-beam etching have a modulation of the line width with two-fold symmetry, suggesting that the crystal planes are modulated by the groove slopes. Dislocations to accommodate mismatch between hcp-Co alloy grains sitting on adjacent slopes of grooves might induce the preferred crystalline orientation
Prioritizing linear equality and inequality systems: Application to local motion planning for redundant robots (2009)

We present a novel method for prioritizing both linear equality and inequality systems and provide one algorithm for its resolution. This algorithm can be summarized as a sequence of optimal resolutions for each linear system following their priority order. We propose an optimality criterion that is adapted to linear inequality systems and characterize the resulting optimal sets at every priority level. We have successfully applied our method to plan local motions for the humanoid robot HPR-2. We will demonstrate the validity of the method using an original scenario where linear inequality constraints are solved at lower priority than equality constraints.
Anatomical Characteristics of Capparis spinosa L. in Tibet (2012)

To further explore the Qinghai-Tibet Plateau plant distinctive physiology structure and its environmental adaptability,the anatomical structures of Capparis spinosa L.from 4 000 m altitude of Zhada in Tibet were studied by the methods of paraffin section.The results showed that the anatomical structure was highly adapted to its environment of mountain desert grassland: periderm of secondary root is developed,the cork is thicker,there is a larger proportion of secondary xylem;There are epidermal hairs and obvious cuticle on the epidermis of stems,and also developed collenchyma tissue,pith is narrow in stems;The leaf is isobilateral with multilayer palisade tissues.Dense stomata exists and significant cuticles are existed in epidermis;Corolla is larger with white petals,which is suitable for insect pollination;Parietal placentation with much ovules in each locule,extine is thicker which can resistant to corrosion,acid and alkaline.All of the characteristics of C.spinosa L.described above result from Qinghai-Tibet Plateau stresses of extremely ecological conditions,such as high irradiance,cold temperature,low air pressure in the Qinghai-Tibet Plateau,as well as the adaptations of the C.spinosa L.to the Qinghai-Tibet Plateau environments.
Quantitative analysis of polymeric proanthocyanidins in birch leaves with normal‐phase HPLC (2006)

Abstract The proanthocyanidin composition and content in the leaves of nine birch species ( Betula albosinensis , B . ermanii , B . maximowicziana , B . nana , B . papyrifera , B . pendula , B . platyphylla , B . pubescens , and B . pubescens ssp. czerepanovii ) were studied with different methods including colorimetric assay, HPLC coupled with PAD or ESI/MS and NMR. Total proanthocyanidin content was determined using the acid butanol assay. A normal phase‐HPLC method was applied for the analysis of polymeric proanthocyanidins. The content of polymeric proanthocyanidins was estimated from a late eluting peak in the chromatogram. With this HPLC method, quantitative analysis of polymeric proanthocyanidins could be performed directly from leaf extracts: no additional purification or preparation steps were required. It was shown that birch leaves contained mainly polymeric proanthocyanidins with a degree of polymerisation greater than 10. Total proanthocyanidin content (expressed as dry weight) was found to vary from 44 mg/g ( B . papyrifera ) to 145 mg/g ( B . nana ), and polymeric proanthocyanidin content from 39 mg/g ( B . pendula ) to 119 mg/g ( B . nana ). Copyright © 2006 John Wiley & Sons, Ltd.
Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia (2010)

The microenvironment provides essential growth and survival signals to chronic lymphocytic leukemia (CLL) cells and contributes to their resistance to cytotoxic agents. Pharmacologic inhibition of spleen tyrosine kinase (SYK), a key mediator of B-cell receptor (BCR) signaling, induces apoptosis in primary CLL cells and prevents stroma contact-mediated cell survival. This report demonstrates a role of SYK in molecularly defined pathways that mediate the CLL-microenvironmental crosstalk independent from the BCR. Chemokine and integrin stimulation induced SYK phosphorylation, SYK-dependent Akt phosphorylation, and F-actin formation in primary CLL cells. Inhibition of SYK by 2 pharmacologic inhibitors and siRNA-knockdown abrogated downstream SYK signaling and morphologic changes induced by these stimuli. CLL cell migration toward CXCL12, the major homing attractor, and CLL cell adhesion to VCAM-1, a major integrin ligand expressed on stromal cells, were markedly reduced by SYK inhibition. In combination with fludarabine, the SYK inhibitor R406 abrogated stroma-mediated drug resistance by preventing up-regulation of the antiapoptotic factor Mcl-1 in CLL cells. SYK blockade in CLL is a promising therapeutic principle not only for its inhibition of the BCR signaling pathway, but also by inhibiting protective stroma signals in a manner entirely independent of BCR signaling.
Ultraviolet Sensing Technology Developments at ITT (1986)

A photon-counting microchannel plate (MCP) photomultiplier tube (PMT) has been developed having a 28 mm active optical input diameter and ultraviolet solar-blind sensitivity. Its quantum yield is high in the uv, eg 10% at 250 nm, while the unwanted long wavelength response is greatly reduced, eg only 1.7E-6% at 600 nm. By using MCPs, this new PMT is one of the smallest to be developed to date for uv solar-blind applications. A potted assembly containing this tube and a high-voltage power supply is only 16 mm long, it has an outside diameter of 52 mm, and its mass is only 50 g. Prototype units have passed MIL-E-5400 environmental tests for class-1B equipment. Several other types of uv optical detectors are discussed which allow sub-nanosecond events to be recorded, which detect the arrival rates and locations of single photons within a 25 mm active diameter, and which have increased quantum efficiency in the far uv.
Design and Efficiency of Selection Experiments for Estimating Genetic Parameters (1971)

(i) Formulae are derived for the sampling variance of selection response and for estimates of realised heritability and realised genetic correlation. (ii) If a control population is maintained, or divergent selection practised, the greater part of the sampling variance comes from genetic drift and depends primarily on the total number of individuals recorded in the whole experiment, rather than on its duration. (iii) The optimal selection intensity for estimating realised heritabilities is investigated-proportions selected of about 15 per cent should be satisfactory. Similar designs will also be efficient for estimation of realised genetic correlations. (iv) Several methods of estimating heritability are compared, of these the realised heritability has least variance. (v) Some selection indices for improving a single trait are evaluated. Mass selection is likely to be best for comparing response from alternative selection programmes or populations.
Enabling one-dimensional nanostructured materials through electrochemistry with novel template development (2022)

This dissertation outlines a generally applicable electrochemistry-based approach towards the creation of template-directed monocrystalline nanowires. The project is presented as essentially two distinct components: nanoporous template development and control of the electrocrystallization of cadmium sulfide. A novel multilayer thin film adaptation of the familiar nanoporous anodic alumina template has been developed allowing the in situ removal of the electrically insulating alumina barrier layer at the pore bases. This barrier-free nanoporous template enables the electrodeposition of a wide variety of materials and ultimately serves as the thread interconnecting the two projects of template development and nanowire synthesis. The first half of this dissertation describes in detail the creation of the multilayer thin film precursor consisting of an Al anodization layer, a Ti diffusion barrier layer and a Pt active electrode underlayer on a Si-substrate. Three interlaced problems were solved towards the development of the multilayer template. Michael Matthew Crouse Firstly, Al-Pt or Al-Au thin film bilayers were found to create intermetallic compounds at the interface. Secondly, the Pt or Au present in the intermetallics deleteriously accelerated the OER side reaction during anodization of the Al thin film to form alumina. Thirdly, an accelerated OER prevented field-driven etching of the oxide barrier layer; thereby, not allowing the creation of the Pt active electrode at the pore bases. The solution to these interlaced problems was the deposition of a selectively removable Ti diffusion barrier layer between the Al and Pt layers. Following the successful development of this Si-based multilayer template, a 'transparent' (25-27 % transmission) extension was developed by shrinking the Pt underlayer and using a float glass substrate. CdS was chosen as the prototypical material due the rich literature base and the ability to easily probe the microstructure using optical techniques. This electrocrystallization study is examined through the unifying concept of the electrochemical overpotential of the cathodic redox reaction. The overpotential components relating to: electrode kinetics, species transport within the pore, and crystallization are demonstrated to be separable. It is shown through the use of DC galvanostatic electrodeposition and the geometric confinement of the statistics of nucleation, that the crystalline quality of the nanowires can be controlled. The limiting case of monocrystalline nanowires can be achieved at low galvanostatic deposition rates where the system is allowed to choose its most energetically favorable nucleation overpotential. At the end of the work, an application of the project towards II-VI nanostructured solar cells is discussed with on-going and future work identified.
Current concepts in laceration repair (1997)

Lacerations account for a significant number of emergency department and urgent care clinic visits for pediatric patients. Children represent a unique challenge in repairing lacerations because of their developmental and behavioral characteristics, making rapidity, ease of performance, and minimal pain particularly desirable. This review focuses on three concepts in laceration repair where there have been significant advances in the past several years in terms of new techniques and drugs. New pharmacologic modalities such as the fentanyl oralet for sedation of children are discussed as well as important nonpharmacological techniques such as parental presence. Topical administration of anesthetics such as tetracaine, adrenaline, and cocaine and lidocaine, epinephrine, and tetracaine offers the advantage of replacing lidocaine infiltration and provides an effective, safe, and painless alternative for local anesthesia. Finally, the introduction of cyanoacrylate tissues adhesives such as Histoacryl Blue (Trihawk International, Montreal, Canada) and Dermabond (Ethicon, Somerville, NJ) appear to be an ideal technique for laceration closure in children because they are easy and rapid to apply, are relatively painless, eliminate the need for suture removal, and provide an acceptable cosmetic result.