gebhart/patrepeval huggingface dataset:
Measurement of ultrasonic pressure by heterodyne interferometry with a fiber-tip sensor (1999)

A fiber-optic measurement system is described that allows ultrasound to be detected in fluids. It is based on a heterodyne interferometer, and the sensing element consists of a metal-coated fiber tip. The heterodyne technique permits direct acquisition of the sound pressure. The required ac photodetection is carried out with wide bandwidth, and the system provides high temporal and spatial resolution. For optimum performance the system parameters are matched to the sound-wave properties of the current application with the aid of theoretical and numerical calculations. The fiber-optic sensor system was applied to two problems of ultrasonic exposimetry in which the favorable features of the measurement technique were exploited. Shock waves from an electromagnetic lithotripter were investigated by use of the wide bandwidth of the system, and the subharmonic in an ultrasonic cleaner was detected, which indicates cavitation.
Inhibitors of Zn-dependent metallopeptidases: synthesis and activity of N-(2-furoyl)-(Z)-alpha, beta-didehydroleucyl-L-tryptophan. (1993)

In order to gain information on structure activity relationships of peptidic inhibitors of Zn-dependent metalloproteinases "hemorrhagins", the conformationally restricted model N-(2-furoyl)-(Z)-alpha,beta-didehydroleucyl-L-tryptophan 2 was synthesized and its activity compared to that of related previously studied substrates. The new model 2 exhibits an inhibitory activity on proteinase II from Crotalus Adamanteus snake venom, sensibly lower than that of related substrates. This result indicates that the reduction of the conformational space due to the presence of the alpha,beta-didehydro-amino acid residue in 2 does not favour the fitting and binding at the enzyme active site.
Person Re-Identification by Dual-Regularized KISS Metric Learning (2016)

Person re-identification aims to match the images of pedestrians across different camera views from different locations. This is a challenging intelligent video surveillance problem that remains an active area of research due to the need for performance improvement. Person re-identification involves two main steps: feature representation and metric learning. Although the keep it simple and straightforward (KISS) metric learning method for discriminative distance metric learning has been shown to be effective for the person re-identification, the estimation of the inverse of a covariance matrix is unstable and indeed may not exist when the training set is small, resulting in poor performance. Here, we present dual-regularized KISS (DR-KISS) metric learning. By regularizing the two covariance matrices, DR-KISS improves on KISS by reducing overestimation of large eigenvalues of the two estimated covariance matrices and, in doing so, guarantees that the covariance matrix is irreversible. Furthermore, we provide theoretical analyses for supporting the motivations. Specifically, we first prove why the regularization is necessary. Then, we prove that the proposed method is robust for generalization. We conduct extensive experiments on three challenging person re-identification datasets, VIPeR, GRID, and CUHK 01, and show that DR-KISS achieves new state-of-the-art performance.
ChemInform Abstract: An Expeditious Route to Streptococci and Enterococci Glycolipids via Ring‐Opening of 1,2‐Anhydrosugars with Protic Acids. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
High Throughput Transcriptome Profiling of Lithium Stimulated Human Mesenchymal Stem Cells Reveals Priming towards Osteoblastic Lineage (2013)

Human mesenchymal stem cells (hMSCs) present in the bone marrow are the precursors of osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for osteoregenerative therapy. However, achieving directed differentiation into osteoblasts has been a major concern. The use of lithium for enhancing osteogenic differentiation has been documented in animal models but its effect in humans is not clear. We, therefore, performed high throughput transcriptome analysis of lithium-treated hMSCs to identify altered gene expression and its relevance to osteogenic differentiation. Our results show suppression of proliferation and enhancement of alkaline phosphatase (ALP) activity upon lithium treatment of hMSCs under non-osteogenic conditions. Microarray profiling of lithium-stimulated hMSC revealed decreased expression of adipogenic genes (CEBPA, CMKLR1, HSD11B1) and genes involved in lipid biosynthesis. Interestingly, osteoclastogenic factors and immune responsive genes (IL7, IL8, CXCL1, CXCL12, CCL20) were also downregulated. Negative transcriptional regulators of the osteogenic program (TWIST1 and PBX1) were suppressed while genes involved in mineralization like CLEC3B and ATF4 were induced. Gene ontology analysis revealed enrichment of upregulated genes related to mesenchymal cell differentiation and signal transduction. Lithium priming led to enhanced collagen 1 synthesis and osteogenic induction of lithium pretreated MSCs resulted in enhanced expression of Runx2, ALP and bone sialoprotein. However, siRNA-mediated knockdown of RRAD, CLEC3B and ATF4 attenuated lithium-induced osteogenic priming, identifying a role for RRAD, a member of small GTP binding protein family, in osteoblast differentiation. In conclusion, our data highlight the transcriptome reprogramming potential of lithium resulting in higher propensity of lithium "primed" MSCs for osteoblastic differentiation.
Development of multilayered woven panels with integrated stiffeners in the transverse and longitudinal directions for thermoplastic lightweight applications (2013)

Weaving technique offers a large potential for the highly productive manufacture of woven 3D-preform structures in lightweight applications. This research work reports on the technological modification to the construction of a double-rapier weaving machine for the low damage production of double-walled shell structures made from glass/polypropylene hybrid yarn multilayered woven fabrics. On this basis, 3D-woven preform structures with integrated stiffeners in the longitudinal and transverse directions for high composite strength and rigidity within a single weaving process were developed and implemented. Furthermore, textile engineering solutions were acquired for the required reinforcement of the gusset area between the stiffener and the skin. This broadens the range of uses for large-scale fiber-reinforced plastics with integrated stiffeners made from 3D-woven preform structures.
Cytotoxic Impacts of Linear and Branched Polyethylenimine Nanostructures in A431 Cells (2011)

These results highlight that, despite induction of Akt-kinase, the BPEI can elicit apoptosis in target cells.
Cationic Quaternary Polyelectrolytes—A Literature Review (1970)

Abstract This paper is a literature survey of quaternary ammonium, sulfonium, and phosphonium polymers.
The Biomechanics of Lower Extremity Action in Distance Running (1987)

The role of quantitative biomechanical measurements in the evaluation of the running patient is discussed. Many techniques are now available to provide insight into the external mechanics of lower extremity action during running, and results from such measurements are presented for symptom-free subjects at distance running speeds. Details of stride length, stride time, and foot placement are first presented followed by a discussion of kinematic data, including stick figures, angle-time graphs, and angle-angle diagrams for the sagittal plane motion of the hip, knee, and ankle joints. The measurement of rearfoot motion, as an approximation of coronal plane subtalar joint movements, is also discussed. Results from acceleration, force, and pressure measurements are considered, and the assertion is made that bilateral asymmetry in many of these measures is a fairly common finding. There are, at present, few reports in the literature of the application of biomechanical techniques to the evaluation of patients with running injuries. It is anticipated that there will be rapid developments in this area in the future and that this will provide considerable insight into the etiology, diagnosis, and treatment of running injuries.
Effects of Hypoxia on the Immunomodulatory Properties of Adipose Tissue-Derived Mesenchymal Stem cells (2013)

Adipose tissue-derived mesenchymal stem cells (ASC) are of great interest as a cellular therapeutic agent for regenerative and immunomodulatory purposes. The function of ASC adapts to environmental conditions, such as oxygen tension. Oxygen levels within tissues are typically much lower than under standard culture conditions and ASC used for therapy therefore encounter a change from normoxic to hypoxic conditions. The effect of hypoxia on the regenerative potential of ASC has been investigated in a number of studies. The effect of hypoxia on the immunomodulatory function of ASC, however, remains to be determined. In the present study the effect of hypoxic (1% oxygen) culture conditions on human ASC was examined. ASC showed no signs of toxicity under low oxygen levels and no major immunophenotypical changes were observed, apart from a down regulation of the marker CD105. Oxygen tension had no effect on the proliferation of ASC and colony forming unit efficiency remained the same under 1 and 20% oxygen. Under both oxygen levels ASC were capable of strong upregulation of the immunomodulatory molecules indoleamine 2,3-dioxygenase (IDO) and programed death ligand-1 upon stimulation with IFN-γ and TNF-α, and, in addition, IDO activity as measured by the accumulation of l-kynurenine was not affected under hypoxia. The ability of ASC to inhibit anti-CD3/CD28 stimulated CD4(+) and CD8(+) T cell proliferation was not hampered by hypoxia. The results of the present study demonstrate that the immunosuppressive capacity of ASC is maintained under hypoxic conditions. These findings are important for the therapeutic use of ASC and may be applied for the in vitro generation of ASC with improved functionality for therapeutic use.
Isolation and expression of the gene for a major surface protein of Giardia lamblia. (1990)

To study the interactions between the parasitic protozoan Giardia lamblia and its environment, we have cloned the gene that encodes the two major surface-labeled trophozoite protein species. Sequence analysis of this gene reveals a single open reading frame specifying a hydrophilic, cysteine-rich (11.8%) protein of 72.5-kDa molecular mass with an amino-terminal signal peptide and a postulated hydrophobic membrane-spanning anchor region near the carboxyl terminus. Most of the cysteine residues (58 of 84) are in the motif Cys-Xaa-Xaa-Cys, which is dispersed 29 times throughout the sequence. Antibodies against the recombinant protein react with the entire surface of live trophozoites, including flagella and adhesive disc. These antibodies inhibit trophozoite attachment, prevent growth, and immunoprecipitate the major approximately 66- and 85-kDa proteins from surface-labeled live trophozoites. The recombinant Escherichia coli also expresses polypeptides of approximately 66- and 85-kDa molecular mass, which are not fusion proteins. This suggests that the processing and/or conformational changes that lead to production of these two peptide species in E. coli reflect those that occur in Giardia. The abundance of cysteine residues suggests that the native proteins on the parasite surface may contain numerous disulfide bonds, which would promote resistance to intestinal fluid proteases and to the detergent activity of bile salts and would help to explain the survival of Giardia in the human small intestine.
Micafungin-Induced Suicidal Erythrocyte Death (2016)

Micafungin triggers hemolysis and eryptosis with cell shrinkage and phospholipid scrambling of the erythrocyte cell membrane.
Bi–Pd Catalyst for Selective Hydrodechlorination of 1,1,2-Trichlorotrifluoroethane to Trifluoroethene, a Key Intermediate to 1,1,1,2-Tetrafluoroethane as a CFC Replacement for Refrigeration (1991)

Abstract Trifluoroethene, a key intermediate to 1,1,1,2-tetrafluoroethane (FC-134a), was catalytically synthesized with 80–90% selectivity at 80–100% conversion in the hydrodechlorination of 1,1,2-trichlorotrifluoroethane(FC-113) at 200–250 °C under an atmospheric pressure over Bi–Pd (Bi/Pd = 0.4–0.6) supported on metal oxides.
Rotor–Stator Interactions in a 2.5-Stage Axial Compressor—Part I: Experimental Analysis of Tyler–Sofrin Modes (2019)

Abstract This two-part paper investigates the influence of rotor–stator interactions on the blade vibrational stresses of the first rotor, excited by the downstream stator. To this end, aeroacoustic and aeroelastic measurements and numerical setup studies for the solver TRACE are conducted in order to improve the predictive accuracy of blade vibrational stresses. Part I compares tip timing data for resonance crossings of three blisk modes to numerical predictions. Due to the single-row analysis within the linearized version of the flow solver TRACE, unsteady rotor–stator interactions are excluded by default. The findings show that leaving out these interactions in the numerical setup can lead to 97% lower vibrational stress predictions with respect to the absolute value measured. To validate the prediction of rotor–stator interactions by the nonlinear frequency domain method of TRACE, unsteady pressure measurements were conducted at the casing in the inter-row section of the first stage. The results were analyzed using an optimized measuring grid and applying a compressed sensing-based azimuthal mode analysis. Predicted azimuthal mode numbers are in accordance with the experiment, whereas amplitudes deviate from the measurements in part. Part II focuses on the prediction of blade vibrational stresses. To this end, a detailed grid study is performed and comparisons to steady and unsteady measurement data are made. In summary, this two-part paper confirms the importance of rotor–stator interactions for blade vibrational stresses excited by downstream vanes at a state-of-the-art high-pressure compressor.
Demonstration of formaldehyde dehydrogenase activity in formaldehyde-resistant Enterobacteriaceae (1991)

Clinical isolates of different Enterobacteriaceae strains and genetically modified variants which were resistant to the disinfectant formaldehyde were investigated. In cell-free extracts of all formaldehyde-resistant strains a glutathione-dependent formaldehyde dehydrogenase activity was demonstrated. In contrast cell extracts from formaldehyde-sensitive strains did not show any formaldehyde dehydrogenase activity. The enzymatic degradation of formaldehyde seems to play an important role in formaldehyde resistance.
Special issue on robust control design from data: direct and model based approaches (2004)

The typical problem a control designer has to face in most practical situations can be briefly described as follows: a control law has to be designed, able to drive a plant to reach given performance specifications. The plant typically is not known, but some prior information on it is available and it is possible to perform some kind of input-output measurements.
Strands, Gravity and Botanical Tree Imagery (1994)

Abstract This paper presents a technique for the modelling and rendering of realistic botanical tree images. A strand model is used that is analogous to the internal vascular structure of a tree. The model is “grown” under the simulated influence of gravity and light. The strand densities at each branching point are used to determine branching angles, branch lengths and branch thicknesses, taking into account stored, user definable parameters that characterize the species of tree being modelled. These parameters address such factors as gravimorphism, phototropism, orthotropism, plagiotropism, planartropism and phyllotaxis, and are distributed according to a branch ordering system. Branch segments and joints are modelled by Bézier splines, with an assumed circular cross‐section. Leaves are made up from numbers of sample ranges from vector plane equations. The trees are rendered using a surface sampling algorithm with a light Z buffer for shadows and autoregression textures for tree bark and grass.
Continuous-wave lasing at room temperature in InGaSbAs/GaAlSbAs injection heterostructures emitting in the spectral range 2.2–2.4 μm (1988)

Room-temperature cw lasing was achieved in InGaSbAs/GaAlSbAs heterostructure injection lasers emitting in the range 2.2–2.4 μm. A stripe geometry with a ridge waveguide was used. The threshold currents in the cw regime were 80–150 mA at T = 300 K.
Magnavox Automatic Vehicle Location Pilot System for the Toronto Department of Ambulance Services (2003)

The AVLS integrates several technologies in a manner that permits satisfaction of demanding requirements, and allows for significant growth and application customizing. Principal examples of this integration are the navigation subsystem, communication subsystem, and AVLS base station dispatch software. Each of these subsystems is described, and how they address the specific needs of the application is illustrated. The ability to tailor the system to other AVLS requirements is also discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Distributed Morphology Approach to Argument Encoding in Kambera  (2008)

In the Malayo-Polynesian language Kambera definite arguments are encoded on the verb via clitics whose form varies between person, number and case. These markers show many instances of syncretism below the clitic level. The aim of this article is to derive the distribution of the homonymous inflection markers and thereby to motivate that syncretic forms do not appear accidentally, as stated in the Syncretism Principle in Müller (2004). The main insight is that we find a correlation between the items' specificity, that means the number of features they realize, and their sonority – a principle called Iconicity by Wiese (1999) – that has until now exclusively been stated for some Indo-European languages. This fact strengthens the hypothesis that iconicity qualifies as a meta-grammatical principle for the architecture of morphological systems.
Kinetic properties of enzyme populations in vivo: alkaline phosphatase of the Escherichia coli periplasm (1992)

Studies were conducted to determine the role that diffusion may play in the in vivo kinetics of the Escherichia coli periplasmic enzyme, alkaline phosphatase (AP, encoded by the gene pho A). Passive diffusion of solutes, from solution into the periplasm, is thought to occur mainly through porins in the outer membrane. The outer membrane therefore serves as a diffusion barrier separating a population of periplasmic enzymes from bulk substrate. E. coli strains containing a plasmid with the pho A gene linked to the lac promoter were used in this study in order to vary the amount of enzyme per cell. Alkaline phosphatase assays were conducted with intact cells, and the substrate concentration at half-maximum velocity (normally the Km for the enzyme) was determined as a function of enzyme concentration per cell. The results showed that diffusion of substrate to the enzyme caused as much as a 1000-fold change in this parameter, compared to that of purified enzyme. This suggested that diffusion was the rate-limiting step of the enzymatic reaction in these cells. In agreement with this type of reaction, Eadie-Hofstee and Lineweaver-Burk plots were not linear. At their extremes, these plots represented two types of kinetics. At high substrate concentration, equilibrium of substrate between bulk solution and the periplasm was achieved, and the kinetic properties conformed to Michaelis-Menten. At low substrate concentrations, there were a large number of free (unbound) enzymes, and each substrate molecule that entered the periplasm, through the diffusion barrier, resulted in product formation.(ABSTRACT TRUNCATED AT 250 WORDS)
BEDSR-Net: A Deep Shadow Removal Network From a Single Document Image (2020)

Removing shadows in document images enhances both the visual quality and readability of digital copies of documents. Most existing shadow removal algorithms for document images use hand-crafted heuristics and are often not robust to documents with different characteristics. This paper proposes the Background Estimation Document Shadow Removal Network (BEDSR-Net), the first deep network specifically designed for document image shadow removal. For taking advantage of specific properties of document images, a background estimation module is designed for extracting the global background color of the document. During the process of estimating the background color, the module also learns information about the spatial distribution of background and non-background pixels. We encode such information into an attention map. With the estimated global background color and attention map, the shadow removal network can better recover the shadow-free image. We also show that the model trained on synthetic images remains effective for real photos, and provide a large set of synthetic shadow images of documents along with their corresponding shadow-free images and shadow masks. Extensive quantitative and qualitative experiments on several benchmarks show that the BEDSR-Net outperforms existing methods in enhancing both the visual quality and readability of document images.
Rearrangements in the genome of the bacterium Salmonella typhi. (1995)

We have determined the genomic map of the bacterium Salmonella typhi Ty2, the causal organism of typhoid fever, by using pulsed-field gel electrophoresis. Digestion of the Ty2 genome with endonucleases Xba I, Bln I, and Ceu I yielded 33, 26, and 7 fragments, respectively, that were placed in order on a circular chromosome of 4780 kb. Transposon Tn10 was inserted in specific genes of Salmonella typhimurium and transduced into S. typhi, and thus, the positions of 37 S. typhi genes were located through the Xba I and Bln I sites of the Tn10. Gene order on chromosomes of Escherichia coli K-12 and S. typhimurium LT2 is remarkably conserved; however, the gene order in S. typhi Ty2 is different, suggesting it has undergone major genomic rearrangements during its evolution. These rearrangements include inversions and transpositions in the 7 DNA fragments between the seven rrn operons for rRNA (postulated to be due to homologous recombination in these rrn genes), another inversion that covers the replication terminus region (resembling inversions found in other enteric bacteria), and at least three insertions, one as large as 118 kb. Partial digestion of genomic DNA with the intron-encoded endonuclease I-Ceu I, which cuts only in rrn genes, shows chromosomal rearrangements, apparently due to homologous recombination in the rrn genes, that were detected in all wild-type strains of S. typhi tested. These rearrangements may have been selected to compensate for the insertions that otherwise would have altered the locations of genes with respect to the origin and terminus of replication. These observations are relevant to our view of the evolution of the bacterial genome and may be significant in the virulence of S. typhi.
Clinical Experience with the Dalkon Shield (1973)

Clinical Experience with the Dalkon Shield SIR,-Dr