gebhart/patrepeval huggingface dataset:
Prevalence of Antineutrophil Cytoplasmic Antibodies in a Large Inception Cohort of Patients with Connective Tissue Disease (1997)

Patients with connective tissue disease are known to develop multiple autoantibodies; positivity for anti-PR3 and anti-MPO ANCA in such patients is highly specific for anti-PR3. However, P-ANCA immunofluorescence, which may have positive results because of the presence of antinuclear antibodies, is not a specific marker of anti-MPO. A rigorous ANCA testing system that combines the results of immunofluorescence with those of ELISA is highly specific for Wegener granulomatosis and related vasculitides even in patients with connective tissue disease.
The oxidized form of glutathione (1999)

). Cell refinement: DIF4. Data reduction: REDU4 (Stoe & Cie
Synthesis of Some Chromanone Derivatives and the Use of DNA in Evaluation of their Biological Activity (1998)

Abstract 6-Formyl-7-hydroxy-5-methoxy-2-pentamethylenechromanone (2) was prepared from the naturally occurring “Visnagin” and condensed with benzil, o-phenylenediamine and 3,4-diaminobenzophenone to give the corresponding imidazolylchromanone derivatives 3-5. Knoevenagel reaction of compound 2 with different active methylene compounds afforded benzodipyranone derivatives 12a - c which may be considered as analogues to the naturally occurring “Xanthyletin and Graveolone Compounds”. The structural formula of the new compounds were established by using different methods for their preparation in addition to the instrumental analyses. Some compounds in this study were biologically evaluated for their ability to bind to DNA.
Dielectric relaxation in the smectic-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow><mml:mi>A</mml:mi></mml:mrow><mml:mrow><mml:mo>/</mml:mo><mml:mi>e</mml:mi><mml:mi>m</mml:mi><mml:mi>p</mml:mi><mml:mi>h</mml:mi><mml:mo>></mml:mo><mml:mn/></mml:mrow></mml:msup></mml:mrow></mml:math>and smectic-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow><mml:mi>C</mml:mi></mml:mrow><mml:mrow><mml:mo>/</mml:mo><mml:mi>e</mml:mi><mml:mi>m</mml:mi><mml:mi>p</mml:mi><mml:mi>h</mml:mi><mml:mo>></mml:mo><mml:mn/></mml:mrow></mml:msup></mml:mrow></mml:math>phases of a ferroelectric liquid crystal (1989)

The results of a study of the dielectric properties of a room-temperature ferroelectric liquid crystal in the frequency range from 5 Hz to 13 MHz are presented here. Measurements of complex electric permittivity versus temperature have been taken on aligned samples of different thicknesses with the electric measuring field being parallel or perpendicular to the layer planes. In homogeneously aligned samples two dielectric relaxation regions have been observed in the smectic-${C}^{\mathrm{*}}$ phase, one known as the Goldstone mode and the other showing up in the vicinity of the smectic-${C}^{\mathrm{*}}$--smectic-${A}^{\mathrm{*}}$ transition called the soft mode. In homeotropically aligned samples the low-frequency molecular relaxation was observed in both smectic phases. Temperature dependences of both dielectric increments and relaxation times suggest that the system studied exhibits a ferroelectric phase transition of the first-order type.
Automated Hyperspectral Cueing for Civilian Search and Rescue (2009)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Hyperspectral remote sensing provides information related to surface material characteristics that can be exploited to perform automated detection of targets of interest and has been applied to a variety of remote sensing applications. This paper explores the application to civilian search and rescue, using the Airborne Real-time Cueing Hyperspectral Enhanced Reconnaissance (ARCHER) system developed for the Civil Air Patrol as a key example of how evolving hyperspectral technology can be employed to support these operations. ARCHER combines a visible/near-infrared hyperspectral imaging system, a high-resolution visible panchromatic imaging sensor, and an integrated geopositioning and inertial navigation unit with onboard real-time processing for data acquisition and correction, precision image georegistration, and target detection and cueing. Processing for detecting downed aircraft wreckage and other related objects employs real-time adaptive anomaly detection and matched filtering algorithms, and a non-real-time change detection mode to provide further false alarm reduction in some instances. This paper describes the system technology, with an emphasis on the current and evolving automated target detection methods, and summarizes the operational experience in the airborne employment against civilian search and rescue missions. </para>
Surface based wireless power transmission and bidirectional communication for autonomous robot swarms (2008)

We introduce an inexpensive, low complexity power surface system capable of simultaneously providing wireless power and bidirectional communication from a surface to multiple mobile robots. This system enables continuous operation of a swarm-sized population of battery-less robots. Our first prototype consists of a 60 cm times 60 cm power surface that provides power and bidirectional communication to an initial evaluation group of five test robots, each one consuming 200 mW. Unlike typical non-resonant inductive (transformer) coupling, power transmission in this system is achieved through magnetic flux coupling between a high Q L-C resonator placed beneath the operating surface and a non-resonant pickup coil on each robot. We explore the design of the pickup coil and conditioning circuitry, and we characterize the position-dependent power density of a static load representative of a small autonomous robot operating on the surface. We demonstrate a continuous power density averaging 4.1 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> for a static load, and develop much greater peak power for dynamic loads via capacitor storage and power conditioning circuitry. We also demonstrate simultaneous broadcast communication between the surface and all robots via amplitude modulation of the magnetic field, and communication between individual robots and the surface via load modulation.
Characterizing reliability in a product/process design-assurance program (1998)

Just as estimates of cost and program timing are critical factors to be known and monitored during a new product development program, so too is the reliability perspective. This paper describes an approach to reliability modeling that encompasses the impact of both product and manufacturing process design on the distribution (characterizing the uncertainty) of reliability over time. It further describes the elicitation of expert judgment which is used to quantify the initial reliability estimate, including uncertainty. Finally, it describes a Bayesian updating approach which is applicable throughout the development program, and which accommodates a wide variety of possible new information. Although the model is rigorous in its execution; a user-friendly approximation is also described which may be useful to the product development team for purposes of test and validation planning.
Synthesis and Reactivity of Alkoxy, Aryloxy, and Dialkylamino Phosphazene Azides (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSynthesis and Reactivity of Alkoxy, Aryloxy, and Dialkylamino Phosphazene AzidesMichael B. McIntosh, Thomas J. Hartle, and Harry R. AllcockView Author Information Department of Chemistry, The Pennsylvania State University 152 Davey Laboratory, University Park, Pennsylvania 16802 Cite this: J. Am. Chem. Soc. 1999, 121, 4, 884–885Publication Date (Web):January 14, 1999Publication History Received28 September 1998Published online14 January 1999Published inissue 1 February 1999https://pubs.acs.org/doi/10.1021/ja983424qhttps://doi.org/10.1021/ja983424qrapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views711Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Aromatic compounds,Azides,Hydrocarbons,Reaction products,Solvents Get e-Alerts
Coincidence Method (1955)

PREVIOUS ARTICLENational Academy of Sciences: Abstracts of Papers Presented at the Autumn Meeting, 2-4 November 1955, California Institute of Technology, Pasadena
Two-phase schema matching in real world relational databases (2008)

We propose a new approach to the problem of schema matching in relational databases that merges the hybrid and composite approach of combining multiple individual matching techniques. In particular, we propose assigning individual matchers to two categories, “strong” matchers that provide apriori higher quality matches, and “weak” matchers that may be more sensitive to the inputs and are less reliable but can still help generate some matches. Matching is correspondingly done in two phases, with strong “matches” being produced by strong matchers being combined using a simple voting combiner, and weak matchers providing additional evidence for attributes left unmatched (again using a voting combiner). We observe that, while many recent advances in schema matching [2][5][7][11] use composite schema matching and rely on the existence of training schemas to train combiners, in many real-world situations it is not feasible to employ learning techniques because of the unavailability of training data (i.e., schemas or instance data.) We hypothesize that “weak” matchers can often hurt overall accuracy if used in a “single-phase” composite matcher that does not employ learning techniques. We implement our two-stage approach in the ASID system and evaluate it using real life schemas. The experiments validate our hypothesis regarding the negative effect of “weak” matchers and also show ASID performs comparably to state of the art systems while requiring no training schemas. We also demonstrate the benefits of a simple documentation-based matcher. Our experimental data included schemas ranging from 20 to 120 attributes. Note that schemas with 120 attributes are as large or larger than other published evaluations of relational schema matching.
Development and In Vitro Characterization of Chitosan-based Microspheres for Nasal Delivery of Promethazine (2007)

Conventional and composed promethazine-loaded microspheres were prepared by spray drying of chitosan solution systems and double water-in-oil-in-water (W/O/W) emulsion systems, respectively. Double emulsions were prepared in two different feed concentrations, with chitosan dissolved in both water phases, and ethylcellulose dissolved in oil phase. Swelling and bioadhesive properties of the microspheres depended on the chitosan content, type and the feed concentration of spray-dried system. Results obtained suggested that better ethylcellulose microcapsules with promethazine in the chitosan matrix were formed when less concentrated emulsion systems were spray-dried. Thus, in case of such a system, with ethylcellulose/chitosan weight ratio of 1:2, prolonged promethazine release was obtained.
Highly transparent and low resistance gallium-doped indium oxide contact to p-type GaN (2005)

We report on a transparent gallium-doped indium oxide (GIO) ohmic contact to the p-GaN. The GIO contact film yielded a low specific contact resistance of 8.1×10−5Ωcm2 on p-GaN when annealed at 600 °C under a nitrogen ambient. The low specific contact resistance can be attributed to the formation of acceptorlike Ga vacancies and an InN or InxGa1−xN phase at the interface between the GIO and p-GaN films. The forward voltage of a light-emitting diode (LED) with a GIO ohmic layer was slightly increased by 0.2 V compared to that of a LED with a standard Ni∕Au contact. However, a light transmittance of 85.7%, which was higher than that of indium tin oxide, was observed in the GIO film at a wavelength of 470 nm after thermal annealing at 600 °C. These results suggest that the GIO contact scheme is suitable for use as a highly transparent and low specific contact resistance contact layer for p-GaN.
Antioxidative and Prooxidative Action of Stilbene Derivatives (2000)

The effects of stilbene derivatives, including resveratrol, diethylstilboestrol and stilbene, as antioxidants or prooxidants were examined. Resveratrol and diethylstilboestrol, but not stilbene, strongly inhibited NADPH- and adenosine 5'-diphosphate (ADP)-Fe3+-dependent lipid peroxidation at the initial and propagation stages. In addition, phenolic stilbenes also inhibited ultraviolet light-induced lipid peroxidation. Resveratrol and diethylstilboestrol efficiently scavenged 2,2'-azobis-(2-amidinopropane)-dihydrochloride peroxyl radicals. However, 2,2'-diphenyl-p-picrylhydrazyl radicals were trapped only by resveratrol, but not by diethylstilboestrol. These results suggest that the inhibitory effect of phenolic stilbenes on lipid peroxidation was due to their scavenging ability of lipid peroxyl and/or carbon-cantered radicals. Resveratrol efficiently reduced ADP-Fe3+, but not EDTA-Fe3+. Stilbenes and diethylstilboestrol did not reduce either ADP-Fe3+ or EDTA-Fe3+. The strand breaks of DNA were stimulated during the interaction of resveratrol with ADP-Fe3+ in the presence of H2O2. These results suggest that phenolic stilbenes act as antioxidants of membrane lipids and that resveratrol has a prooxidative effect DNA damage during interaction with ADP-Fe3+ in the presence of H2O2.
Towards a Biocatalyst for ( <i>S</i> )-Styrene Oxide Production: Characterization of the Styrene Degradation Pathway of <i>Pseudomonas</i> sp. Strain VLB120 (1998)

In order to design a biocatalyst for the production of optically pure styrene oxide, an important building block in organic synthesis, the metabolic pathway and molecular biology of styrene degradation in Pseudomonas sp. strain VLB120 was investigated. A 5.7-kb XhoI fragment, which contained on the same strand of DNA six genes involved in styrene degradation, was isolated from a gene library of this organism in Escherichia coli by screening for indigo formation. T7 RNA polymerase expression experiments indicated that this fragment coded for at least five complete polypeptides, StyRABCD, corresponding to five of the six genes. The first two genes encoded the potential carboxy-terminal part of a sensor, named StySc, and the complete response regulator StyR. Fusion of the putative styAp promoter to a lacZ reporter indicated that StySc and StyR together regulate expression of the structural genes at the transcriptional level. Expression of styScR also alleviated a block that prevented translation of styA mRNA when a heterologous promoter was used. The structural genes styA and styB produced a styrene monooxygenase that converted styrene to styrene oxide, which was then converted to phenylacetaldehyde by StyC. Sequence homology analysis of StyD indicated a probable function as a phenylacetaldehyde dehydrogenase. To assess the usefulness of the enzymes for the production of enantiomerically pure styrene oxide, we investigated the enantiospecificities of the reactions involved. Kinetic resolution of racemic styrene oxide by styrene oxide isomerase was studied with E. coli recombinants carrying styC, which converted styrene oxide at a very high rate but with only a slight preference for the S enantiomer. However, recombinants producing styrene monooxygenase catalyzed the formation of (S)-styrene oxide from inexpensive styrene with an excellent enantiomeric excess of more than 99% at rates up to 180 U g (dry weight) of cells-1.
Towards the Isomer‐Specific Synthesis of Higher Fullerenes and Buckybowls by the Surface‐Catalyzed Cyclodehydrogenation of Aromatic Precursors (2010)

Fullerenes on a plate: A surface-catalyzed cyclodehydrogenation reaction enabled selective fullerene-cage formation from polycyclic organic precursors. As no CC bond rearrangement occurred during the reaction, only specifically designed precursors gave the desired fullerene (see picture). This efficient and selective condensation process opens new horizons in the directed synthesis of fullerenes and related structures.
Catalytic properties of copper oxide supported on zinc aluminate in methane combustion (1991)

Copper oxide was deposited on a zinc aluminate prepared from high specific area alumina and zinc nitrate. The activity of the solid obtained has been measured in the catalytic combustion of methane before and after an aging test performed at 1340 K. The environment of the copper species was followed by UV–VIS reflectance spectroscopy whereas the state of copper was deduced from temperature-programmed reduction experiments. By comparison with a series of CuO/Al2O3 catalysts, the CuO/ZnAl2O4 sample is slightly less active in the complete oxidation of methane. This decrease in catalytic activity is connected with the presence of bulk CuO particles on the zinc aluminate support instead of isolated copper ions in the case of the alumina carrier.Slight deactivation was observed after the aging test at 1340 K whereas the CuO/Al2O3 system was strongly deactivated under the same conditions. Spectroscopic and TPR experiments have shown that the copper oxide phase was preserved in the case of the zinc aluminate supported copper oxide. The formation of the copper aluminate phase at the origin of the dramatic loss in activity of the aged CuO/Al2O3 catalyst barely occurs when copper oxide is supported on zinc aluminate.
Microstructure Approach to Property Optimization in Wrought Superalloys (1974)

The effects of structure control available from the precipitating phases in wrought superalloys were demonstrated in a recent review. It was shown that criteria for selection of superalloys should be reviewed periodically to establish that they reflect the state of the art. For example, expensive materials may have been specified where lower cost alloys could do a job equally well. This is especially true for superalloys in applications where properties up to about 1200°F are critical. This paper reviews some results of the continuing study by superalloy metallurgists to reveal means of “retrograding” elevated temperature requirements to lower cost compositions that, combined with proper processing, will meet property requirements. It is shown that microstructure studies, combined with knowledge of phase relationships, prove to be an invaluable tool. Recent examples of improved hot-work behavior, heat-treat response, and property development are reviewed. Effects of thermomechanical processing are also discussed.
CDMA Based Wireless Transceiver System MATLAB Simulation and FPGA Implementation (2005)

Code Division Multiple Access (CDMA) has become the technology of choice for the current and future generation of wireless systems. We have implemented the CDMA IS-95 based Wireless Transceiver System using Matlab Simulink v 7.0. The entire system is implemented using the Xilinx System Generator Block v6.3. Even though the CDMA IS-95 system is already implemented in Simulink and is provided as a demo, there is no way of converting it into real Hardware. Using Xilinx System Generator we have made our implementation capable of being translated into any of the HDL codes. This can be then mapped onto appropriate FPGA easily. We have used the hardware co-simulation feature of the Xilinx System generator to create a library of the basic building blocks of the IS-95 system. This library can be used for implementing to create the various channels that are the part of the CDMA system.
Evolutionarily Conserved Noncoding DNA in the Human Genome: How Much and What For? (2001)

The noncoding component of the human genome is receiving increased attention from biologists because of its predicted role in regulation of transcription, DNA replication, chromosome pairing, and chromosome condensation. Finding the functional elements within this 97% of the human genome presents major intellectual and experimental challenges. By comparing genomic DNA sequence from diverse species, functional elements may be recognized on the basis of their evolutionary conservation. In this issue, Frazer et al. ( In a twoway comparison between mouse and human, they found that the amount of conserved noncoding sequence was roughly equal to the coding sequence in this region. One-half of the human/mouse conserved noncoding sequence was also conserved in a third mammal, the dog. This work produced a catalog of potential functional elements for chromosome 21 that will be valuable to future studies of gene regulation and chromosome mechanics. In addition, a method for identification of conserved sequences prior to genome sequencing is shown.
Studies on the Experimental Chemotherapy for Dermatomycosis and Candidiasis.V : On the Antifungal Activity for Various Arylhaloacetamide Compounds in Vitro and in Vivo (1968)

The 55 derivatives of arylhaloacetamide, which were synthesized, were tested for their fungicidal and bactericidal properties against Trichophyton asteroides and other fungal or bacterial pathogens in vitro. Outstanding among them was N-(α-naphthyl)iodoacetamide (NIA), which was found to combine a strong fungicidal action with less skin irritation and toxity to mammals compared to pentachlorophenol (PCP) as a control substance. The results of therapeutic test in guinea pigs revealed that a hydrophilic ointment containing 1-2% NIA had about 50% cure rate on experimental candidiasis and dermatomycosis, and that containing PCP or salicylic acid besides NIA, about 60%.
Definition and Distribution Analysis of Glycoprotein B Gene Alleles of Human Herpesvirus 7 (1998)

As for other herpesviruses, glycoprotein B (gB) of human herpesvirus 7 (HHV-7) is believed to play a major role in virus infection and as a target of the host immunogenic response. Using nested PCR, we amplified the whole HHV-7 gB gene from 108 human peripheral blood mononuclear cell samples and studied its variability. By means of restriction fragment length polymorphism (RFLP) analysis, three distinct patterns, designated I, II, and III, were defined and detected at frequencies of 93, 5, and 2%, respectively. Determination of the nucleotide sequence allowed us to recognize five critical positions in the gB gene with six specific combinations of point changes at these positions. These combinations were gB alleles A, B, C, D, E, and F. Alleles D and E corresponded to RFLP patterns II and III, respectively, while the other four alleles corresponded to RFLP pattern I. Identical gB alleles were detected in serial samples as well as in paired samples of blood and saliva from the same individuals, except for one case. In contrast, the distribution of gB alleles differed according to the geographical origin of the human samples: C was the most frequent allele in both African and Caribbean samples, whereas F was the most frequent allele in European ones. Although none of the allele-specific nucleotide changes induced any modification at the protein level, the definition of gB alleles provided convenient viral markers for the study of both HHV-7 infections and human population genetics.