gebhart/patrepeval huggingface dataset:
Superconductivity Seen at Record High Temperatures in Metal Oxides (1987)

RETURN TO ISSUEPREVNewsNEXTSuperconductivity Seen at Record High Temperatures in Metal OxidesIn the course of a few months, research groups have pushed the record temperature for inorganic superconductivity from 23.2 K to 52.5 KRON DAGANIView Author Information C&EN WashingtonCite this: Chem. Eng. News 1987, 65, 5, 29–30Publication Date (Print):February 2, 1987Publication History Published online8 November 2010Published inissue 2 February 1987https://pubs.acs.org/doi/10.1021/cen-v065n005.p029https://doi.org/10.1021/cen-v065n005.p029newsACS PublicationsCopyright © 1987 American Chemical SocietyArticle Views12Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Electrical properties,Materials,Oxides,Superconducting transition,Superconductivity Get e-Alerts
Activity of topical antifungals on infected sites. Skin permeability and adsorption to horny materials. (1990)

Butenafine hydrochroride(KP-363; N-4-tert-butylbenzyl-N-1-methyl-1-naphthalene-methylamine hydrochloride)の皮膚への浸透性および貯留性を14C-KP-363を用い検討した。1%14C-KP-363 0.2ml(2mg)をモルモットの背部皮膚に6時間密封貼付した後の皮膚の各層への分布を検討したところ, KP-363は白癬の生息部位である角層を含む表皮層には50μg/g以上存在し, 貼布24時間後(貼付終了18時間後)でも表皮層には10μg/g以上の薬剤の残存が認められ, 本剤はbarrierを含む表皮層に貯留しやすいことが判明した。一方, 抗真菌剤と角質との吸着性をヒト毛髪粉末を用い検討したところ, KP-363, tolnaftate, clotrimazoleおよびbifonazoleは毛髪と強い吸着が観察された。毛髪に吸着したKP-363, tolnaftate, clotrimazoleおよびbifonazoleのT. mentagrophytesに対する抗菌力はそれぞれ4.0, 15.6, 62.5および62.5μg/g(毛髪)であり, サブロー液体培地で測定した抗菌力(0.0125, 0.05, 0.39および0.39μg/ml)に比べ減弱していた。しかし, 1%KP-363を塗布した場合に得られる角層中のKP-363濃度はT. mentagrophytesの発育を阻止するになお充分であることが明らかとなつた。
The Difference Between Calibration and Image Linearity (1996)

Abstract In my last article, I discussed the need for scheduled system checks on scanning electron microscopes. The article used an experience at a local SEM laboratory to point out the importance of monitoring your instrument by performing simple but regular system performance evaluations. In this article I will discuss some principles behind the performance of imaging systems such as scanning electron and scanning probe microscopes. We will talk about the concepts of image linearity and dimensional calibration.
Piezoresistive cantilevers utilized for scanning tunneling and scanning force microscope in ultrahigh vacuum (1994)

Piezoresistive cantilevers have been utilized in a novel ultrahigh vacuum scanning probe microscope which allows in situ scanning tunneling microscopy (STM), contact atomic force microscopy (AFM), and noncontact atomic force microscopy. The instrument uses interchangeable tungsten tips (for STM imaging) and piezoresistive cantilevers (for AFM or STM imaging) and is capable of atomic resolution in both STM and AFM modes of operation. In situ tip exchange under vacuum conditions is performed quickly and reliably using a high precision rotary/linear feedthrough and a tip/cantilever storage system. Piezoresistive force-sensing cantilevers provide a new detection scheme for AFM, using an all-electronic detector that requires no alignment or optical detection system. The microscope features a high-resolution, dual-axis, inertial-drive translation stage with an open access sample mount designed to optimize vibration isolation.
The S1P<sub>2</sub> Receptor Negatively Regulates Platelet-Derived Growth Factor-Induced Motility and Proliferation (2005)

Sphingosine-1-phosphate (S1P), a bioactive sphingolipid metabolite, is the ligand for five specific G protein-coupled receptors, named S1P(1) to S1P(5). In this study, we found that cross-communication between platelet-derived growth factor receptor and S1P(2) serves as a negative damper of PDGF functions. Deletion of the S1P(2) receptor dramatically increased migration of mouse embryonic fibroblasts toward S1P, serum, and PDGF but not fibronectin. This enhanced migration was dependent on expression of S1P(1) and sphingosine kinase 1 (SphK1), the enzyme that produces S1P, as revealed by downregulation of their expression with antisense RNA and small interfering RNA, respectively. Although S1P(2) deletion had no significant effect on tyrosine phosphorylation of the PDGF receptors or activation of extracellular signal-regulated kinase 1/2 or Akt induced by PDGF, it reduced sustained PDGF-dependent p38 phosphorylation and markedly enhanced Rac activation. Surprisingly, S1P(2)-null cells not only exhibited enhanced proliferation but also markedly increased SphK1 expression and activity. Conversely, reintroduction of S1P(2) reduced DNA synthesis and expression of SphK1. Thus, S1P(2) serves as a negative regulator of PDGF-induced migration and proliferation as well as SphK1 expression. Our results suggest that a complex interplay between PDGFR and S1P receptors determines their functions.
Increased expression of the transcription factors CCAAT-enhancer binding protein-Β (C/EBΒ) and C/EBPζ (CHOP) correlate with invasiveness of human colorectal cancer (2000)

Regulation of cell differentiation is most often impaired in malignant tumors and may represent a key mechanism for the progression of the disease. CCAAT-enhancer binding protein (C/EBP) is a family of transcription factors involved in the regulation of embryonic gut development in rodents, which has also been detected in various malignancies, e.g., liposarcomas and breast and ovarian epithelial tumors. We studied the relationship between C/EBP and tumor histology (Duke's invasive stage and pathological grade) in colorectal cancer. Immunoblotting techniques were used on microdissected fresh frozen tumor specimens, and expression of C/EBPα, C/EBPβ and C/EBPζ (CHOP) was analyzed in addition to that of the cell-cycle regulator p53 and the proliferation marker PCNA. Expression of C/EBPβ (LAP isoforms) was markedly increased in all tumors compared with normal colon mucosa. Although the inter-patient variability was large, we found that LIP, the isoform of C/EBPβ known to inhibit transcription, was expressed at higher levels in Duke's stage B tumors compared with Duke's stage A, whereas Duke's C tumors had the lowest LIP expression. A similar relationship was seen for CHOP. The cell-cycle regulator gene p53 was the only factor that clearly correlated with pathological grade: a decrease in p53 expression was demonstrated. Our data suggest that genetic and cellular events involving C/EBPβ and CHOP are important for tumor invasion and that these events do not appear to be related to the pathological grade of the tumor. Int. J. Cancer 86:337–343, 2000. © 2000 Wiley-Liss, Inc.
Thermische und photochemische Additionen von Dienophilen an Arene sowie deren Vinyloge und Hetero-Analoge; II (1980)

2. Reactions of Aliphatic-Aromatic Diene Systems with Dienophiles 2.1. Reactions of Styrenes (Vinylbenzenes) 2.1.1. Characteristic Types of Addition to Styrene Moieties 2.1.2. Oligomerization, Polymerization, and Co-Polymerization of Styrenes and Related Compounds 2.1.3. Addition of Dienophiles to Substituted Styrenes, Coumarins, Chromenes, and Styrylchromenes 2.1.4. Intramolecular Cycloaddition Reactions of Styryl Derivatives 2.1.5. 1,1-Diphenylethylenes (α-Phenylstyrenes) 2.1.6. Stilbenes 2.2. Reactions of Styrene Analogs 2.2.1. Aza Analogs of Styrenes and Stilbenes (Azines, vic-Diimines), Schiff Bases, Ketene Imines 2.2.2. Indenes, 3-Vinylindenes 2.2.3. Dihydronaphthalenes 2.2.4. Vinylnaphthalenes, 1-Vinyl-3,4-dihydronaphthalene 2.2.5. 2,2′-Binaphthyl 2.2.6. Indoles, Vinylindoles 2.2.7. Indolizines 2.2.8. Nitrovinyl-pyrroles and -benzindoles 2.2.9. 2-Vinylfurans 2.2.10. 2-Vinylthiophenes 2.2.11. Vinylpyridines, 2-Vinylquinoline 2.2.12. Vinylanthracenes 2.2.13. 9-Vinylphenanthrenes 2.2.14. Vinylpyrenes, Vinylferrocenes 2.2.15. Phenafulvenes 2.2.16. 9-Alkylidenefluorenes 2.2.17. Diazoazoles 2.2.18. 4(5)-Vinylimidazole
Surgery in papillary thyroid carcinoma: A review of 730 patients (1988)

Between 1956 and 1978, 1143 patients with thyroid cancer, nearly half of all patients with thyroid carcinomas in Norway in this period, were seen in our hospital. Of 730 papillary cancer patients, 447 were operated with total thyroidectomy (TT), 179 with hemi-thyroidectomy (HT), while 104 patients had minor thyroid resections (RT). Survival and recurrence rates were similar in the TT- and HT-groups. Local recurrences were seen in 15.2% of the patients following total thyroidectomy and in 16.2% following hemi-thyroidectomy; distant metastases were seen in 10.7% and 11.2%, respectively. Beyond the seventh year of follow-up the cumulative survival was similar following total thyroidectomies, hemi-thyroidectomies, and thyroid resections. Unless grossly malignant residues were left behind, the impact of the surgical procedure on prognosis in papillary thyroid cancer seems minor.
Out with a Bang! Tetrahymena as a Model System to Study Secretory Granule Biogenesis (2003)

The release of polypeptides in response to extracellular cues is a notable feature of endocrine, exocrine and neuronal cells, and is based on regulated exocytosis via dense-core secretory granules. There is interest in this mode of secretion because of its importance in human physiology and also because regulated exocytosis reflects a complex pathway of membrane traffic that includes compartment-specific reversible macromolecular assembly, coat-independent vesicle budding, maturation/remodeling of both lumenal and membrane constituents, and stimulus-dependent membrane fusion. Secretory granules are absent in most unicellular model organisms but are highly developed in the Ciliates, which therefore offer attractive systems to study these phenomena. In Tetrahymena thermophila, biochemical and genetic approaches have begun yielding insights into issues ranging from control of granule core assembly, based on reverse genetic analysis of granule cargo, to questions about factors involved in granule biogenesis, based on random mutational approaches.
Characterization of a nuclear protein that binds to three elements within the silencer region of a bean chalcone synthase gene promoter. (1991)

The chalcone synthase (EC 2.3.1.74) gene promoter from the bean Phaseolus vulgaris L. contains a silencer element between positions -140 and -326 fro the transcription start site that is functional in electroporated soybean protoplasts. This element contains three binding sites for a bean nuclear factor (SBF-1) with DNA sequence recognition properties that are very similar to those of nuclear factor GT-1. By using a synthetic tetramer of one of the binding sites as probe, we have purified sequence-specific SBF-1 activity approximately 1750-fold from suspension-cell nuclei, by using a combination of ammonium sulfate precipitation, gel filtration, heparin-agarose chromatography, and sequence-specific DNA affinity chromatography. The factor exhibited an apparent molecular weight of 160,000-200,000 on the basis of gel filtration. A subunit molecular weight of approximately 95,000 was determined from SDS/polyacrylamide gel electrophoretic analysis of purified fractions, followed by Southwestern blot analysis (a protein blot probed with oligonucleotide probes), and from UV-cross-linking experiments. The factor lost DNA-binding activity on treatment with alkaline phosphatase. We discuss the properties of SBF-1 in relation to the functionality of GT-1 binding sequences in plant genes.
Robust Method for Removing Dynamic Objects from Point Clouds (2020)

3D point cloud maps are an accumulation of laser scans obtained at different positions and times. Since laser scans represent a snapshot of the surrounding at the time of capture, they often contain moving objects which may not be observed at all times. Dynamic objects in point cloud maps decrease the quality of maps and affect localization accuracy, hence it is important to remove the dynamic objects from 3D point cloud maps. In this paper, we present a robust method to remove dynamic objects from 3D point cloud maps. Given a registered set of 3D point clouds, we build an occupancy map in which the voxels represent the occupancy state of the volume of space over an extended time period. After building the occupancy map, we use it as a filter to remove dynamic points in lidar scans before adding the points to the map. Furthermore, we accelerate the process of building occupancy maps using object detection and a novel voxel traversal method. Once the occupancy map is built, dynamic object removal can run in real-time. Our approach works well on wide urban roads with stopped or moving traffic and the occupancy maps get better with the inclusion of more lidar scans from the same scene.
Inside quality evaluation of fruit by X-ray image (2004)

In this paper, soft X-ray transmission images and X-ray CT images were discussed for a fruit quality inspection. Split-pits of peach fruits could be detected through transmission images in a real time, and information of water content distribution and internal structure of fruit were given by CT images and CT numbers. It was considered that a total fruit quality evaluation system would be completed when this X-ray imaging information was combined with ultra-violet, visible, infrared, and other region information.
Plasmonic Nanoholes in a Multichannel Microarray Format for Parallel Kinetic Assays and Differential Sensing (2009)

We present nanohole arrays in a gold film integrated with a six-channel microfluidic chip for parallel measurements of molecular binding kinetics. Surface plasmon resonance effects in the nanohole arrays enable real-time, label-free measurements of molecular binding events in each channel, while adjacent negative reference channels can record measurement artifacts such as bulk solution index changes, temperature variations, or changing light absorption in the liquid. With the use of this platform, streptavidin-biotin specific binding kinetics are measured at various concentrations with negative controls. A high-density microarray of 252 biosensing pixels is also demonstrated with a packing density of 10(6) sensing elements/cm(2), which can potentially be coupled with a massively parallel array of microfluidic channels for protein microarray applications.
Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers. (2000)

The tumor grade (Gleason score) in the biopsy and pretherapy prostate-specific antigen level do not accurately predict disease outcome of individual patients' prostate cancer. We used a rapid colorimetric in situ hybridization technique to evaluate the expression level of E-cadherin (which affects cell cohesion); matrix metalloproteinases (MMPs) types 2 and 9 (which affect invasion); and vascular endothelial growth factor/vascular permeability factor (which affects angiogenesis) in archival prostatectomy specimens from 40 patients. Intratumoral heterogeneity for gene expression (edge versus center versus perineural area) was more pronounced in advanced cancers than in those that were organ confined. Regardless of Gleason score, the highest expression level for E-cadherin was found in the center or perineural area of the tumors, whereas the highest expression levels for MMP-2 and MMP-9 were associated with the invasive edge. The relationship between advancing pathological stage and expression of all four metastasis-related genes was highly significant. Decreased expression of E-cadherin and increased expression of MMP-2, MMP-9, and vascular endothelial growth factor/vascular permeability factor were associated with the Gleason score of the tumors. Irrespective of serum prostate-specific antigen level or Gleason score, the ratio between expression of MMPs and E-cadherin at the invasive edge of tumors exhibited the strongest association with nonorgan-confined prostate cancer. These data suggest that the relative expression of metastasis-related genes in radical prostatectomy specimens can distinguish between organ-confined and advanced prostate cancers and provides the rationale for a prospective study correlating gene expression in pretherapy core biopsies with outcome.
INCREASING THE CALCIUM CONTENT OF MEALWORMS (TENEBRIO MOLITOR) TO IMPROVE THEIR NUTRITIONAL VALUE FOR BONE MINERALIZATION OF GROWING CHICKS (2000)

The purpose of these studies was to determine the husbandry variables that optimize the Ca content of mealworms (Tenebrio molitor) and to determine the bioavailability of this Ca for bone mineralization in chicks that consume the mealworms. To determine the optimal level of Ca in the substrates used in short-term (< 14 days) holding of mealworms and to determine the length of time that mealworms should be exposed to high-Ca substrates, mealworms were placed in either a wheat bran or a chicken starter substrate supplemented with 0, 4, 8, or 12% Ca from CaCO3. The mealworms were harvested after 0.5, 1, 2, 3, 4, 7, or 14 days. The Ca content of the mealworms was greatest with the use of chicken starter and increased linearly with the Ca content of the substrate. In general, the Ca content of the mealworms increased during the first 24 hr and decreased after > or = 1 wk, especially at the higher levels of Ca supplementation. The chicken starter also resulted in higher levels of vitamin D in mealworms. Mealworms held in wheat bran with 8% Ca were fed to growing chicks. Ca bioavailability was calculated from the chicks' bone ash. The Ca in these mealworms was 76% as bioavailable as the Ca in oyster shell.
Strong immunostimulation in murine immune cells by Lactobacillus rhamnosus GG DNA containing novel oligodeoxynucleotide pattern (2005)

Whole cells, cell wall components and some soluble factors from Lactobacillus rhamnosus GG (LGG) are known to invoke immune responses as they interact with animal and human immune cells. In the present study, we found that chromosomal DNA from LGG is a potent inducer of splenic B cell proliferation, CD86/CD69 expression and cytokine production in mice. In the genomic DNA of LGG we discovered TTTCGTTT oligodeoxynucleotide (ODN) ID35, which has a potent activity in a number of immunostimulatory assays. Phosphorothioate backbone is not required for the activity of ID35. The ODN ID35 showed levels of activity comparable with those induced by the murine prototype ODN 1826 in B cell proliferation, CD86/CD69 expression, interleukin (IL)-6, IL-12, IL-18, interferon gamma (IFN-gamma) and tumour necrosis factor alpha (TNF-alpha) mRNA expression and IFN-gamma/IL-12p70 protein production assays. Additionally, ID35 appeared to be equally active in both murine and human immune cells. These stimulatory effects are due to TTTCGTTT motif located in the 5' end of ID35. In this study we demonstrate for a first time that, DNA from LGG is a factor of immunobiotic activity. Furthermore, ODN ID35 is the first ODN, with such a strong immunostimulatory activity to be found in immunobiotic bacterial DNA.
Adhesive monomers to dental ceramics. II. Methacrylamide derivatives containing carboxyl and phenyl groups for effective adhesion of calcium metaphosphate ceramic (1994)

Abstract Twelve methacrylamide derivatives containing carboxyl and phenyl groups have been evaluated as adhesives for calcium metaphosphate ceramic, a promising but hard‐to‐adhere cast ceramic restoration material. Although methacrylamide monomers having a carboxyl group showed low adhesive tensile strength for the ceramic, contrary to the glycidyl methacrylate derivatives, the monomer having neighboring two carboxyl groups at the phenyl ring exhibited quite high adhesion. Moreover, the monomer proved to retain high adhesion strength for the surface‐etched ceramic for a long period of time even in water and would thus be suitable for practical clinical applications. © 1994 John Wiley & Sons, Inc.
A performance measurement and system evaluation project plan proposal (1985)

This document is an outline for a performance measurement and evaluation effort. Performance measurements consist of producing data showing frequency and execution times for components of computer systems. Components implies:1)hardware2)ucode3)macrocode4)applications software5)systems (e.g., utilities in an operating-system environment)Evaluation can be broken down into several areas. Principle areas of interest are comparative performance evaluation and an analysis of a system's structure/behavior. Comparative evaluation consists of: relative performance measurements of different machines; a summary of collected data; and an analysis of a system's structure, including the production of data describing the interrelationship of system components. This data may be narrative, but the preferred technique is a graphical presentation showing component relationships.
Preceding Vehicle Detection Based on Multi-characteristics Fusion (2006)

Preceding vehicle detection is a major research field of safety assistant driving system. This paper proposed a preceding vehicle detection method based on multi-characteristics fusion. First, the areas of interesting for preceding vehicles are established by using the bottom shadows. Then the preceding vehicles are identified through the fusion of vehicle margin characteristics, texture characteristics and vertical edge symmetry. Finally, vehicle location can be acquired by means of vehicle margin information. Experimental results show that this method has good reliability and accuracy.
Configurable SID-based multi-core simulators for embedded system education (2009)

With the emerging of multi-core designs for embedded systems, there is a need of multi-core simulation tools for courseware and class experiments. In this paper, we present a multi-core SID-based simulation framework useful for exercises and hands-on labs for embedded multi-core courses. The SID is a component-based simulation framework upon which a set of simulation components, such as processors, memory, DMAs, LCDs, and other peripherals are built. Our tool includes ingenious MPU IP, and PAC DSP IP with distributed register files. Each of the components is attached with an interconnection adaptor. The adaptor in our design enables the simulation to be done in the functional layer or in the TLM layer for the interconnection networks. Besides, the communication performance of the system can be evaluated in different types of interconnection networks. In addition, our tool supports profiling capability and time-reversible execution, which enables a rich set of experiments in teaching embedded multi-core courses. Finally, we also present a set of possible courses to be based on this set of tools.