gebhart/patrepeval huggingface dataset:
Tonoplast-Bound Protein Kinase Phosphorylates Tonoplast Intrinsic Protein (1992)

Tonoplast intrinsic protein (TIP) is a member of a family of putative membrane channels found in bacteria, animals, and plants. Plants have seed-specific, vegetative/reproductive organ-specific, and water-stress-induced forms of TIP. Here, we report that the seed-specific TIP is a phosphoprotein whose phosphorylation can be monitored in vivo by allowing bean cotyledons to take up [(32)P]orthophosphate and in vitro by incubating purified tonoplasts with gamma-labeled [(32)P]ATP. Characterization of the in vitro phosphorylation of TIP indicates that a membrane-bound protein kinase phosphorylates TIP in a Ca(2+)-dependent manner. The capacity of the isolated tonoplast membranes to phosphorylate TIP declined markedly during seed germination, and this decline occurred well before the development-mediated decrease in TIP occurs. Phosphoamino acid analysis of purified, radiolabeled TIP showed that serine is the major, if not only, phosphorylated residue, and cyanogen bromide cleavage yielded a single radioactive peptide peak on a reverse-phase high-performance liquid chromatogram. Estimation of the molecular mass of the cyanogen bromide phosphopeptide by laser desorption mass spectroscopy led to its identification as the hydrophilic N-terminal domain of TIP. The putative phosphate-accepting serine residue occurs in a consensus phosphorylation site for serine/threonine protein kinases.
Catalytic enantioselective decarboxylative reactions using organocatalysts (2013)

Catalytic decarboxylative reactions are attractive as biomimetic reactions and environmentally friendly reaction processes. In this review, the origin and recent development of organocatalytic enantioselective decarboxylative reactions of malonic acid half oxy- or thioesters, or β-ketoacids are summarized.
The NIST watt balance: progress toward monitoring the kilogram (1997)

The National Institute of Standards and Technology (NIST) watt balance is an experiment to compare measurements of the watt using electrical references (volt, ohm) to those using mechanical references (length, time, mass). A coil within a radial magnetic field has a dual use of: (1) generating a voltage by moving at some velocity to calibrate the magnetic flux density, and, (2) generating a force with electrical current to balance the gravitational force of a mass. This experiment has had several improvements made to it in the last year. These include the incorporation of three-laser interferometry and a refractometer to improve the velocity measurements, temperature control and coil rotation damping to reduce drifts and stabilize laser and mechanical alignments, and a gravimeter to determine local gravity. Systematic errors and scatter in long-term measurements have been greatly reduced in the last year, but statistically significant deviations relative to within-run uncertainty still persist. The source of these deviations has not yet been identified. Recent within-run standard deviations are generally near 0.1 pW/W, which is the target precision of this present design.
Lifelong Learning for Heterogeneous Multi-Modal Tasks (2019)

In this work, we investigate the lifelong learning problem from the viewpoint of heterogeneous multi-modal fusion. The main challenges come from the fact that the common representation between heterogeneous modalities should be persistently learned and the learned classifier for each multi-modal task should be persistently updated. To address this problem, we construct a multi-modal lifelong learning framework which deals with the consecutive multi-modal learning tasks and develop an efficient online dictionary learning algorithm to solve the multi-modal lifelong learning problem. Finally, we perform experimental validation on a complicated material recognition task and show the promising results.
Hani, “Chris” (1942–1993) (2011)

Born in Sabalele, Cofimvaba, in the former Transkei, South Africa, Martin Thembisile “Chris” Hani – a South African communist, nationalist, and popular military leader – was the fifth of six children, three of whom died in infancy. His father was a migrant mineworker and building worker, and his mother engaged in subsistence farming. As a child Hani was an eager student and an altar boy so committed to the Catholic Church that he hoped to become a priest; his father forbade this. In 1953, while Hani was at Matanzima Secondary School, Cala, the apartheid government introduced Bantu education, a system of separate and inferior education for Africans. Hani's anger at this laid the foundation for his political activism.
Pathogenesis and classification of massive periretinal proliferation. (1978)

Massive periretinal proliferation (MPP), a serious complication of retinal detachment, is caused by proliferation and fibrous metaplasia of cells mostly deriving from retinal pigment epithelium and retinal glial cells. Contracting fibrous membranes in the vitreous, and on and also under the retina, cause the intraocular changes of MPP. Early signs such as increased 'tobacco dust', pigmented and unpigmented clumps in the vitreous, and subtle preretinal and even retroretinal membranes are usually overlooked. The late signs such as starfolds, irregular retinal folds, circumferential folds, and funnel-shaped detachments are well known. The pathogenesis of the clinically visible signs is described, and a 4-stage classification of the disease is given.
The Ideal Low-Pass Filter in the form of a Dispersionless Lag Line (1946)

Some theoretical and practical aspects of the design of the ideal low-pass filter in the form of a dispersionless lag line are considered. It is shown, in particular, that an artificial line made up of series inductances and shunt capacitances, with 18 per cent aiding mutual inductance between adjacent coils and 8 per cent shunt capacitance between alternate tie points, forms, for many purposes, a sufficiently good approximation of a dispersionless lag line. The mathematical study of the function f(n) = fo (1 -cos ϕ/ϕ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ) cos nϕdϕ, which is of pertinent interest in lag-line theory, is given in an appendix.
Image Segmentation Method Using Fuzzy C Mean Clustering Based on Multi-Objective Optimization (2018)

Image segmentation is not only one of the hottest topics in digital image processing, but also an important part of computer vision applications. As one kind of image segmentation algorithms, fuzzy C-means clustering is an effective and concise segmentation algorithm. However, the drawback of FCM is that it is sensitive to image noise. To solve the problem, this paper designs a novel fuzzy C-mean clustering algorithm based on multi-objective optimization. We add a parameter λ to the fuzzy distance measurement formula to improve the multi-objective optimization. The parameter λ can adjust the weights of the pixel local information. In the algorithm, the local correlation of neighboring pixels is added to the improved multi-objective mathematical model to optimize the clustering cent. Two different experimental results show that the novel fuzzy C-means approach has an efficient performance and computational time while segmenting images by different type of noises.
Optimal Depth for Nasopharyngeal Temperature Probe Positioning (2016)

Any nasopharyngeal probe insertion depth between 10 and 20 cm well represents core temperature in adults having noncardiac surgery.
Aerosolized Vasodilators in Pulmonary Hypertension (2002)

Pulmonary hypertension is a life-threatening disease characterized by an increase in artery pressure and vascular resistance in the pulmonary circulation. A primary form of pulmonary hypertension with unknown causes is to be distinguished from the far more frequent secondary forms based on known pulmonary and extrapulmonary disorders. An imbalance in the synthesis of vasoconstrictive and vasodilative agents seems to play an important role in the etiology of pulmonary hypertension. This pathophysiological background offers the possibility to develop treatment strategies, including application of vasodilative drugs. The intravenous administration of vasodilative agents, however, lacks pulmonary selectivity leading to systemic side effects. Therefore, the application of aerosol techniques for alveolar deposition of vasodilatory drugs was proposed and several studies with inhaled iloprost, a stable prostacyclin analogue, demonstrated preferential vasorelaxation in the pulmonary circulation, with the maximum pulmonary vasodilatory potency corresponding to that of intravenous prostacyclin. Clinical experiences with long-term inhaled iloprost are available showing sustained effects on exercise capacity and pulmonary hemodynamics in patients with pulmonary hypertension. Due to the necessary frequent inhalations (up to 12 times a day) and the potency of the prostaglandins, the choice of the nebulizer is critical, requiring physical characterization and device comparison studies under the right heart-catheter conditions. The concept of aerosolized vasodilators is meanwhile well established and offers a promising perspective in the treatment of pulmonary hypertension.
Survival with the Acquired Immunodeficiency Syndrome (1987)

In a cohort of 5833 subjects in whom the acquired immunodeficiency syndrome (AIDS) was diagnosed in New York City before 1986, the cumulative probability of survival (mean +/- SE) was 48.8 +/- 0.7 percent at one year and 15.2 +/- 1.8 percent at five years. The group with the most favorable survival rate--white homosexual men 30 to 34 years old who presented with Kaposi's sarcoma only--had a one-year cumulative probability of survival of 80.5 percent; that group was used as the reference group in assessing the effect of five variables: sex, race or ethnic background, age, probable route of acquiring AIDS (risk group), and manifestations of AIDS at diagnosis. The range in the mortality rate was greater than threefold, depending on these variables. Black women who acquired the disease through intravenous drug abuse, for example, had a particularly poor prognosis. The manifestations of disease at diagnosis had the most influence on survival, accounting on average for 56.3 percent of the excess risk. This variable was followed in importance by age (12.2 percent), race or ethnicity (10.6 percent), risk group (8.4 percent), and sex (8.0 percent), with 4.5 percent of the risk attributable to interactions between variables. When we compared subcohorts based on the year of diagnosis (1981 through 1985), we found a significant improvement in the one-year cumulative probability of survival among subjects with Pneumocystis carinii pneumonia, but not among subjects without P. carinii pneumonia.
Mesenchymal stem cells enhance survival and bacterial clearance in murine<i>Escherichia coli</i>pneumonia (2012)

Treatment with MSCs enhanced survival and bacterial clearance in a mouse model of Gram-negative pneumonia. The bacterial clearance effect was due, in part, to the upregulation of lipocalin 2 production by MSCs.
CloudCache: Expanding and shrinking private caches (2011)

The number of cores in a single chip multiprocessor is expected to grow in coming years. Likewise, aggregate on-chip cache capacity is increasing fast and its effective utilization is becoming ever more important. Furthermore, available cores are expected to be underutilized due to the power wall and highly heterogeneous future workloads. This trend makes existing L2 cache management techniques less effective for two problems: increased capacity interference between working cores and longer L2 access latency. We propose a novel scalable cache management framework called CloudCache that creates dynamically expanding and shrinking L2 caches for working threads with fine-grained hardware monitoring and control. The key architectural components of CloudCache are L2 cache chaining, inter- and intra-bank cache partitioning, and a performance-optimized coherence protocol. Our extensive experimental evaluation demonstrates that CloudCache significantly improves performance of a wide range of workloads when all or a subset of cores are occupied.
The therapy of carbamate and organophosphate intoxication with new oximes (1999)

The antidotal effect of bis-imidazolium oxime BDB-122 and quinuclidinium-imidazolium oxime BM-1 was tested in itnoxication with some carbamates and organophosphorus compounds (OPs). Their effectiveness was tested in vitro on human erythrocytes acetylcholinesterase (AChE) and in vivo on mice. Each oxime applied together with atropine had good therapeutic effect in intoxication with carbamates (propoxur, carbaryl, RO-0683) and OPs (dichlorvos and soman). Oxime BDB-122 with atropine protected mice against 16.0 LD50 of propoxur, 2.0 LD50 of carbaryl, 8.0 LD50 of RO2/0683, 22.4 LD50 of dichlorvos, and 2.0 LD50 of soman, whereas oxime BM/1 with atropine yielded a 100 % survival of mice intoxicated with 16.0 LD50 of propxur, 2.5 LD50 of carbaryl, 20.0 LD50 of RO2-0683, 11.5 LD50 of dichlorvos, and 4.0 LD50 of soman. Good therapeutic effect of tested oximes in itnoxication with carbamates is especially interesting, because actually the drug of choice is atropine only.
Attributed Network Embedding via Subspace Discovery (2019)

Network embedding aims to learn a latent, low-dimensional vector representations of network nodes, effective in supporting various network analytic tasks. While prior arts on network embedding focus primarily on preserving network topology structure to learn node representations, recently proposed attributed network embedding algorithms attempt to integrate rich node content information with network topological structure for enhancing the quality of network embedding. In reality, networks often have sparse content, incomplete node attributes, as well as the discrepancy between node attribute feature space and network structure space, which severely deteriorates the performance of existing methods. In this paper, we propose a unified framework for attributed network embedding-attri2vec-that learns node embeddings by discovering a latent node attribute subspace via a network structure guided transformation performed on the original attribute space. The resultant latent subspace can respect network structure in a more consistent way towards learning high-quality node representations. We formulate an optimization problem which is solved by an efficient stochastic gradient descent algorithm, with linear time complexity to the number of nodes. We investigate a series of linear and non-linear transformations performed on node attributes and empirically validate their effectiveness on various types of networks. Another advantage of attri2vec is its ability to solve out-of-sample problems, where embeddings of new coming nodes can be inferred from their node attributes through the learned mapping function. Experiments on various types of networks confirm that attri2vec is superior to state-of-the-art baselines for node classification, node clustering, as well as out-of-sample link prediction tasks. The source code of this paper is available at https://github.com/daokunzhang/attri2vec.
Soft magnetic FeSiBPCu heteroamorphous alloys with high Fe content (2009)

Fe–Si–B amorphous alloys with less than 80 at. % Fe are now in practical use because of their excellent magnetic softness and rather high magnetization (Js) basically owing to the lack of intrinsic magnetic anisotropy and the high Fe content, respectively. A strict upper limit of the Fe content (about 80 at. %) for the formation of a single amorphous phase with good magnetic softness hinders the improvement in Js of the Fe-based amorphous alloys. The alloys with the high Fe content exceeding the limit commonly have the as-quenched structure consisting of coarse α-Fe grains in an amorphous matrix, which inevitably results in inferior magnetic softness. The simultaneous addition of proper amounts of P and Cu is found to be significantly effective in decreasing the grain size of α-Fe phase, formed in an amorphous matrix in the as-quenched Fe82Si9B9 amorphous alloys with high Fe content exceeding the limit. Fe-rich Fe81.7Si9B7P2Cu0.3 heteroamorphous alloy with an as-quenched structure consisting of extremely small α-Fe-like clusters of about 3 nm or smaller in diameter, randomly dispersed within the amorphous matrix, exhibits the lower coercivity of 7 A m−1 and the higher Js of 1.56 T than the typical Fe-based monolithic amorphous alloy at an as-quenched state.
Coordinated and efficient huge page management with ingens (2016)

Modern computing is hungry for RAM, with today's enormous capacities eagerly consumed by diverse workloads. Hardware address translation overheads have grown with memory capacity, motivating hardware manufacturers to provide TLBs with thousands of entries for large page sizes (called huge pages). Operating systems and hypervisors support huge pages with a hodge-podge of best-effort algorithms and spot fixes that made sense for architectures with limited huge page support, but the time has come for a more fundamental redesign.Ingens is a framework for huge page support that relies on a handful of basic primitives to provide transparent huge page support in a principled, coordinated way. By managing contiguity as a first-class resource and by tracking utilization and access frequency of memory pages, Ingens is able to eliminate a number of fairness and performance pathologies that plague current systems. Experiments with our prototype demonstrate fairness improvements, performance improvements (up to 18%), tail-latency reduction (up to 41%), and reduction of memory bloat from 69% to less than 1% for important applications like Web services (e.g., the Cloudstone benchmark) and the Redis key-value store.
Safety in view: A public safety visual analytics tool based on CCTV camera angles of view (2015)

Campus security and police departments have implemented a multitude of safety precautions, including CCTV cameras. The efficiency and effectiveness of using CCTV camera resources for preventing crimes result in higher demand. We implemented a visual analytics tool to analyze the existing CCTV camera resources and suggest improved allocation schemas based on blind spots and crime data. Our tool provides the user with an interactive safe path calculation method for walking purpose on the basis of the maximum monitoring area. Additionally, avoiding buildings in the calculated path is an optional control factor. Our tool also provides functions for crime data analysis. The camera-alarming function highlights the cameras that a specific crime occurred in their visible range. The camera-ranking function highlights the camera that records the largest number of crime incidents. Based on the historical crime data, we suggest locations for future camera installation. We present two case studies to illustrate the usage and features of our tool on the campus of Purdue University.
Instant Human Face Attributes Recognition System (2011)

The objective of this work is to provide a simple and yet efficient tool for human attributes like gender, age and ethnicity by the human facial image in the real time image as we all aware this term that “Real-Time frame rate is a vital factor for practical deployment of computer vision system”. In this particular paper we are trying to presents the progress towards face detection and human attributes classification system. We have developed an algorithm for the classification of gender, age and race from human frontal facial image As the basis of the classifier proposed algorithm uses training set neuron receptors that process visual information a study of the several variants of these classifiers and shows the principal possibility of sex determination, assessment of a person's age on a scale (adult - children) and recognition of race by using the neuron-like receptors.
Actions of some transmitters and their antagonists on salivary secretion in a tick (1978)

Cholinomimetics (pilocarpine, carbachol, physostigmine, acetylcholine, acetyl-beta-methylcholine) and sympathomimetics (dopamine, epinephrine), when injected into the hemolymph, provoked salivary fluid secretion in the female ixodid tick Amblyomma hebraeum Koch. Atropine, but not tubocurarine or toxiferine, abolished pilocarpine-induced secretion without reducing the response to dopamine. Reserpine and guanethidine likewise selectively attenuated pilocarpine-induced secretion. Following extirpation of the synganglion, pilocarpine no longer provoked a secretory response whereas dopamine did. Thus, the salivary gland appears to be innervated directly by catecholaminergic rather than cholinergic secretory nerves. It is suggested that pilocarpine elicits salivation by interacting with muscarinic-type cholinergic receptors situated either on the cell bodies of the secretory nerves, or alternatively in the integrative or sensory pathway.
THE QUINOXALINOLS. I. CORRELATION BETWEEN ANTI-BACTERIAL ACTIVITY AND CHELATING ABILITY (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE QUINOXALINOLS. I. CORRELATION BETWEEN ANTI-BACTERIAL ACTIVITY AND CHELATING ABILITYSTANLEY K. FREEMAN and PAUL E. SPOERRICite this: J. Org. Chem. 1951, 16, 3, 438–442Publication Date (Print):March 1, 1951Publication History Published online1 May 2002Published inissue 1 March 1951https://pubs.acs.org/doi/10.1021/jo01143a016https://doi.org/10.1021/jo01143a016research-articleACS PublicationsRequest reuse permissionsArticle Views222Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts