gebhart/patrepeval huggingface dataset:
Financiamiento y calidad académica en la Universidad Autónoma del Estado de México, 2004-2012 (2015)

En el presente artículo se desarrolla un análisis cuantitativo sobre la relación que guarda el financiamiento en el logro de la calidad académica de las instituciones de educación superior públicas de México en un contexto de políticas públicas eficientistas. Se pretende encontrar si a mayor gasto, mayor calidad académica o si por el contrario el esfuerzo por incrementar el nivel de inversión en el sector educativo no está dando los resultados esperados, para lo anterior se desarrolla un indicador global de calidad académica que resulta de la cuantificación de diversas variables tales como profesores de tiempo completo, eficiencia terminal, proyectos de investigación con financiamiento interno y externo entre otras. Una vez obtenido el indicador de calidad académica se contrasta con el nivel de financiamiento público recibido para conocer si el primero se ha incrementado en relación directa al segundo.
Automatic image annotation by an iterative approach (2007)

Automatic image annotation automatically labels image content with semantic keywords. For instance, the Relevance Model estimates the joint probability of the keyword and the image [3]. Most of the previous annotation methods assign keywords separately. Recently the correlation between annotated keywords has been used to improve image annotation. However, directly estimating the joint probability of a set of keywords and the unlabeled image is computationally prohibitive. To avoid the computation difficulty we propose a heuristic greedy iterative algorithm to estimate the probability of a keyword subset being the caption of an image. In our approach, the correlations between keywords are analyzed by "Automatic Local Analysis" of text information retrieval. In addition, a new image generation probability estimation method is proposed based on region matching. We demonstrate that our iterative annotation algorithm can incorporate the keyword correlations and the region matching approaches handily to improve the image annotation significantly. The experiments on the ECCV2002 [2] benchmark show that our method outperforms the state-of-the-art continuous feature model MBRM with recall and precision improving 21% and 11% respectively.
Similar effects of suspensions of copper oxychloride and kaolin on sprayed leaves* (1972)

SUMMARY When dried on leaves, aqueous suspensions of copper oxychloride and of kaolin damaged the leaves similarly. With both, the damage was correlated with the rate the leaves lost water, which increased as the size of the suspended particles of copper oxychloride decreased. The damage seemed to arise mainly from a physical effect of the particles and not from copper reacting chemically.
Purification and Characteristics of Feruloyl Esterase from <i>Aspergillus awamori</i> G‐2 Strain (2008)

ABSTRACT: For food industry production processes and other uses, a mold that produces high levels of feruloyl esterase was obtained from laboratory mold collections and other sources. It was Aspergillus awamori G‐2 that produces high levels of feruloyl esterase. The feruloyl esterase was purified using ion‐exchange chromatography, size‐exclusion chromatography, and HPLC chromatography. The enzyme was identified as a monomer protein using size‐exclusion chromatography. Its optimum temperature and pH were, respectively, 40 °C and pH 5. Its activity was stable at pH 3 to 5. The enzyme was combined with xylan and starch, but it was absorbed by cellulose. The km of the feruloyl esterase was 0.0019% (0.01 mM). The enzyme showed stable activity at pH 3 and 50 °C, making this enzyme useful for food production.
Robust shadow and illumination estimation using a mixture model (2009)

Illuminant estimation from shadows typically relies on accurate segmentation of the shadows and knowledge of exact 3D geometry, while shadow estimation is difficult in the presence of texture. These can be onerous requirements; in this paper we propose a graphical model to estimate the illumination environment and detect the shadows of a scene with textured surfaces from a single image and only coarse 3D information. We represent the illumination environment as a mixture of von Mises-Fisher distributions. Then, each shadow pixel becomes the combination of samples generated from this illumination environment. We integrate a number of low-level, illumination-invariant 2D cues in a graphical model to detect and estimate cast shadows on textured surfaces. Both 2D cues and approximate 3D reasoning are combined to infer a set of labels that identify the shadows in the image and estimate the positions, shapes and intensities of the light sources. Our results demonstrate that the probabilistic combination of multiple cues, unlike prior approaches, manages to differentiate both hard and soft shadows from the underlying surface texture even when we can only coarsely anticipate the effect of 3D geometry. We also experimentally demonstrate how correct estimation of the sharpness and shape of the light sources improves the augmented reality results.
Lack of directed Vα14‐Jα281 rearrangements in NK1<sup>+</sup> T cells (1997)

NK1.1+ T cells are an unusual subset of TCR alpha beta cells distinguished by their highly restricted V beta repertoire and predominant usage of an invariant V alpha 14-J alpha 281 chain. To assess whether a directed rearrangement mechanism could be responsible for this invariant alpha chain, we have analyzed V alpha 14 rearrangements by polymerase chain reaction and Southern blot in a panel of cloned T-T hybrids derived from thymic NK1.1+ T cells. As expected a high proportion (17/20) of the hybrids had rearranged V alpha 14 to J alpha 281. However, V alpha 14-J alpha 281 rearrangements always occurred on only one chromosome and were accompanied by other V alpha-J alpha rearrangements (not involving V alpha 14) on the homologous chromosome. These data argue that rigorous ligand selection rather than directed rearrangement is responsible for the high frequency of V alpha 14-J alpha 281 rearrangements in NK1.1+ T cells.
The Rights of Students with Learning Disabilities and the Responsibilities of Institutions of Higher Education Under the Americans With Disabilities Act (1994)

WL 470697, at *2 (1st Cir. Nov. 22, 1993) (a morbidly obese person is considered by the medical profession to be one who weighs more than twice his or her optimal weight or 100 pounds more than his or her optimal weight).
Monoamine oxidase inhibitors from Cinchonae Cortex. (1989)

Three strong alkaloidal monoamine oxidase (MAO) inhibitors, quinine (1), cinchonicinol ([ 1S,3'R,4'R]-3-(3-ethenyl-4-piperidinyl)-1-(4-quinolinyl)-1-propanol) (2) and cinchonaminone ([ 3'R,4'S]-2-[2-(3-ethenyl-4-piperidinyl)-acetyl]-1H-indole-3-ethanol) (3), were isolated from Cinchonae Cortex (Cinchona succirubra Pav., Rubiaceae). The structures of 2 and 3 were elucidated on the bases of spectral data and chemical evidence, and 3 is a new alkaloid. The inhibitory effects on MAO of 1, 2, 3 and related alkaloids were assayed. The type of inhibition by 1 with respect to benzylamine as a substrate was competitive.
A Bidirectional Isolated DC–DC Converter as a Core Circuit of the Next-Generation Medium-Voltage Power Conversion System (2007)

This paper describes a bidirectional isolated dc-dc converter considered as a core circuit of 3.3-kV/6.6-kV high-power-density power conversion systems in the next generation. The dc-dc converter is intended to use power switching devices based on silicon carbide (SiC) and/or gallium nitride, which will be available on the market in the near future. A 350-V, 10-kW and 20 kHz dc-dc converter is designed, constructed and tested. It consists of two single-phase full-bridge converters with the latest trench-gate insulated gate bipolar transistors and a 20-kHz transformer with a nano-crystalline soft-magnetic material core and litz wires. The transformer plays an essential role in achieving galvanic isolation between the two full-bridge converters. The overall efficiency from the dc-input to dc-output terminals is accurately measured to be as high as 97%, excluding gate drive and control circuit losses from the whole loss. Moreover, loss analysis is carried out to estimate effectiveness in using SiC-based power switching devices. Loss analysis clarifies that the use of SiC-based power devices may bring a significant reduction in conducting and switching losses to the dc-dc converter. As a result, the overall efficiency may reach 99% or higher
Direct Binding to Ceramide Activates Protein Kinase Cζ before the Formation of a Pro-apoptotic Complex with PAR-4 in Differentiating Stem Cells (2005)

We have reported that ceramide mediates binding of atypical protein kinase C (PKC) zeta to its inhibitor protein, PAR-4 (prostate apoptosis response-4), thereby inducing apoptosis in differentiating embryonic stem cells. Using a novel method of lipid vesicle-mediated affinity chromatography, we showed here that endogenous ceramide binds directly to the PKCzeta.PAR-4 complex. Ceramide and its analogs activated PKCzeta prior to binding to PAR-4, as determined by increased levels of phosphorylated PKCzeta and glycogen synthase kinase-3beta and emergence of a PAR-4-to-phosphorylated PKCzeta fluorescence resonance energy transfer signal that co-localizes with ceramide. Elevated expression and activation of PKCzeta increased cell survival, whereas expression of PAR-4 promoted apoptosis. This suggests that PKCzeta counteracts apoptosis, unless its ceramide-induced activation is compromised by binding to PAR-4. A luciferase reporter assay showed that ceramide analogs activate nuclear factor (NF)-kappaB unless PAR-4-dependent inhibition of PKCzeta suppresses NF-kappaB activation. Taken together, our results show that direct physical association with ceramide and PAR-4 regulates the activity of PKCzeta. They also indicate that this interaction regulates the activity of glycogen synthase kinase-3beta and NF-kappaB.
Nontrivial ambiguities for blind frequency-resolved optical gating and the problem of uniqueness (2004)

Several schemes and methods exist for frequency-resolved optical gating as a technique for the full characterization of ultrashort optical signals as complex electric fields. However, the uniqueness of the reconstructed fields has never been shown. Here we derive conditions that are sufficient for unique reconstruction of the complex pulses. Furthermore, we construct several examples of distinct pulse pairs with identical or essentially identical frequency-resolved optical-gating traces; even examples with identical spectral intensities of the pulse pairs were found.
<title>Iterative Optical Processor (10P) For Adaptive Phased Array Radar Processing</title> (1979)

A non-coherent vector-matrix multiplication system (using a linear LED input array, a covariance matrix mask and a linear photodiode detector array) is described. The system has been modified to perform complex multiplications and by feedback to be an iterative optical processor (I0P) to solve the adaptive phased array radar processing problem.
Label-Free Electrical Detection Using Carbon Nanotube-Based Biosensors (2009)

Label-free detections of biomolecules have attracted great attention in a lot of life science fields such as genomics, clinical diagnosis and practical pharmacy. In this article, we reviewed amperometric and potentiometric biosensors based on carbon nanotubes (CNTs). In amperometric detections, CNT-modified electrodes were used as working electrodes to significantly enhance electroactive surface area. In contrast, the potentiometric biosensors were based on aptamer-modified CNT field-effect transistors (CNTFETs). Since aptamers are artificial oligonucleotides and thus are smaller than the Debye length, proteins can be detected with high sensitivity. In this review, we discussed on the technology, characteristics and developments for commercialization in label-free CNT-based biosensors.
SPECT and PET radiopharmaceuticals for molecular imaging of apoptosis: from bench to clinic (2017)

Owing to the central role of apoptosis in many human diseases and the wide-spread application of apoptosis-based therapeutics, molecular imaging of apoptosis in clinical practice is of great interest for clinicians, and holds great promises. Based on the well-defined biochemical changes for apoptosis, a rich assortment of probes and approaches have been developed for molecular imaging of apoptosis with various imaging modalities. Among these imaging techniques, nuclear imaging (including single photon emission computed tomography and positron emission tomography) remains the premier clinical method owing to their high specificity and sensitivity. Therefore, the corresponding radiopharmaceuticals have been a major focus, and some of them like 99mTc-Annexin V, 18F-ML-10, 18F-CP18, and 18F-ICMT-11 are currently under clinical investigations in Phase I/II or Phase II/III clinical trials on a wide scope of diseases. In this review, we summarize these radiopharmaceuticals that have been widely used in clinical trials and elaborate them in terms of radiosynthesis, pharmacokinetics and dosimetry, and their applications in different clinical stages. We also explore the unique features required to qualify a desirable radiopharmaceutical for imaging apoptosis in clinical practice. Particularly, a perspective of the impact of these clinical efforts, namely, apoptosis imaging as predictive and prognostic markers, early-response indicators and surrogate endpoints, is also the highlight of this review.
Use of volume chirped Bragg gratings for compact high-energy chirped pulse amplification circuits (1998)

Summary form only given. We present the first experimental demonstration of using a volume chirped Bragg grating for ultrashort pulse stretching and recompression in a compact CPA arrangement. Such a device makes it possible to overcome mode-size limitations of a fiber grating and to achieve scalable energies from an all solid-state high-energy CPA system. A chirped volume holographic grating was written in hydrogen-loaded germanosilicate glass.
Fault detection, pulp and paper, biotechnology (1997)

Fault detection, pulp and paper and biotechnology: fault detection methods qualitative modelling methods for fault diagnosis pulp and paper processes control applications in biotechnical processes.
Architecting Self-Tuning Optical Networks (2002)

We describe an IP-optical traffic management system that creates a self-tuning optical core. We show that an adaptive transport layer can significantly improve network efficiencies and thus, reduce capital and operating expenses for the carrier.
Studies on Antitubercular Compounds. X. Condensation Products of Aldehydes and Acid Hydrazides of Pyridine Group (1956)

Nine condensation products of isomeric three aldehydes and three acid hydrazides of pyridine group were prepared and their tuberculostatic activity against virulent human tubercle bacillus, strain H37Rv, was examined on Kirchner's medium containing 10% of bovine serum. The most active compounds were the condensation products of isonicotinic acid hydrazide with aldehydes and stronger than isonicotinic acid hydrazide in vitro.
Oncogene and growth factor expression in MEN 2 and related tumors. (1992)

Pheochromocytomas occur sporadically or in individuals affected by inherited syndromes including multiple endocrine neoplasia (MEN) type 2A and 2B, neurofibromatosis, and the von Hippel-Lindau syndrome (vHL). Medullary thyroid carcinomas (MTCs) also occur sporadically or as part of MEN 2A, MEN 2B, and familial MTC. Little is known of the molecular genetic background of these tumors. We have shown previously that activation of the N-ras, H-ras, and K-ras oncogenes does not occur in these tumors, but that deletions of the short arm of chromosome 1 are extremely common (> 60%) and may indicate loss of a suppressor gene in the chromosomal region 1p31-36. We have examined the structure and expression of N-myc, c-myc, L-myc, c-mos, nerve growth factor (beta-NGF), and the low affinity nerve growth factor receptor (LNGFR) in a series of pheochromocytomas and MTCs from patients with hereditary and sporadic diseases. Southern analysis, using radiolabeled DNA probes, revealed no evidence of amplification or rearrangement of these genes in any normal or tumor tissues except for loss of heterozygosity at the L-myc locus (1p32) in 9 pheochromocytomas from patients with MEN 2A or MEN 2B, in 5 of 11 non-MEN pheochromocytomas, and in 3 of 24 non-MEN MTCs. Gene expression at the RNA level was examined by Northern analysis or ribonuclease protection assay (RPA) using radiolabeled DNA or cRNA probes. C-myc transcripts were detectable at low levels in all tumors tested.(ABSTRACT TRUNCATED AT 250 WORDS)
Identification of rare and novel mutations in the CFTR genes of CF patients in Southern England (1994)

Cystic fibrosis patients referred to two genetics centres in southern England and not found to carry common CF-associated mutations in one or both of their CFTR genes have been subjected to an extensive mutation search. The whole of the coding region of the CFTR gene, all intron-exon boundaries and 5' and 3' untranslated regions have been examined by a combination of single stranded conformational polymorphism analysis and chemical mismatch detection; 48 chromosomes with rare mutations have been identified, including 7 novel mutations, 182delT in exon 1, G27X in exon 2, Q151X in exon 4, Q220X in exon 6a, Q525X in exon 10, 3041delG in exon 16, and 4271delC in exon 23.
In vivo spatio‐temporal visualization of the human skin by real‐time confocal microscopy (1994)

A modified tandem scanning confocal microscope is used to obtain in vivo images of the human skin in real time. Three-dimensional and temporal visualizations are demonstrated with volume reconstruction and blood flow images. Two image processing methods based on Fourier transform and logarithmic processing are presented. Their applications in noise removal of the scanning disk lines and of the heterogeneity of light are illustrated.
Biological control of onion neck rot (<i>Botrytis aclada</i>): Protection of wounds made by leaf topping (1991)

The efficacy of fungal antagonists in protecting onions from neck rot caused by Botrytis aclada was investigated. Leaf wounds made by topping of onions during harvest, which are considered as important entrance sites for B. aclada, were treated with conidial suspensions (5 × 107 conidia ml‐1) of antagonists. In field experiments with artificial inoculation with conidia of B. aclada, applications of Trichoderma viride during harvest reduced the incidence of neck rot, assessed after three months’ storage of the onions at 9° C, from 35% to 24% in 1989 and from 28% to 18% in 1990, when onions initially had been stored under favourable conditions for fungal development. Comparable results were obtained with T. hamatum and Gliocladium roseum. A bioassay based on wound treatment of detached onion leaves was developed to select further antagonists. From 40 candidate antagonists tested, 20 strains gave similar or better control than the strain of T. viride applied in the field experiments. Effective antagonists could be found amongst strains of Trichoderma spp. Gliocladium spp. and Penicillium spp. as well as amongst fungi such as Aureobasidium pullulans and yeasts isolated from green leaves of onion or rye.
A simple route to C-monosubstituted carborane derivatives (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA simple route to C-monosubstituted carborane derivativesFrank A. Gomez and M. Frederick HawthorneCite this: J. Org. Chem. 1992, 57, 5, 1384–1390Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February 1992https://pubs.acs.org/doi/10.1021/jo00031a016https://doi.org/10.1021/jo00031a016research-articleACS PublicationsRequest reuse permissionsArticle Views999Altmetric-Citations94LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Involvement of Indirect Effects in Cell-killing and DNA Double-strand Breakage in γ-irradiated <i>Escherichia Coli</i> K-12 (1976)

(1976). The Involvement of Indirect Effects in Cell-killing and DNA Double-strand Breakage in γ-irradiated Escherichia Coli K-12. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine: Vol. 29, No. 3, pp. 293-296.
GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents (2017)

The complexities of GSK-3β function and interactions with PI3K/AKT/mTOR signaling, cell cycling, and apoptotic pathways are poorly understood in the context of lymphomagenesis and cancer therapeutics. In this study, we explored the anti-tumor effects of the GSK-3β inhibitor, 9-ING-41, in lymphoma cell lines as a single agent and in combination with novel agents comprising BCL-2 inhibitor (Venetoclax), CDK-9 inhibitor (BAY-1143572) and p110δ-PI3K inhibitor (Idelalisib). Treatment of Daudi, SUDHL-4, Karpas 422, KPUM-UH1, and TMD8 lymphoma cell lines with 1 μM 9-ING-41 reduced cell viability by 40-70% (p<0.05) and halted proliferation. Luminex analysis of apoptotic pathways revealed a significant increase in active caspase 3 in all lymphoma cell lines (p<0.001) except TMD8 cells. Co-treating SUDHL-4 and KPUM-UH1 lymphoma cells with 0.5 μM 9-ING-41 showed 8-and 2-fold reduction in IC<sub>50</sub> values of Venetoclax, respectively. No significant benefit for this combination was seen in other lymphoma cells tested. The combination of BAY-1143572 with 0.5 μM 9-ING-41 showed an 8-fold reduction in the IC<sub>50</sub> value of the former in SUDHL-4 lymphoma cells alone. No significant changes in IC<sub>50</sub> values of Idelalisib were measured across all cell lines for the combination of 9-ING-41 and Idelalisib. Further, signaling analysis via Western blot in the double-hit lymphoma cell line, KPUM-UH1, suggests that phospho-c-MYC is modified with 9-ING-41 treatment. Altogether, our data show that 9-ING-41 results in increased apoptosis and decreased proliferation in aggressive B-cell lymphoma cells and enhances the antitumor effects of BCL-2 and CDK-9 antagonists.
A force sensitive multi-touch array supporting multiple 2-D musical control structures (2007)

We describe the design, implementation, and evaluation with musical applications of force sensitive multi-touch arrays of touchpads. Each of the touchpads supports a three dimensional representation of musical material: two spatial dimensions plus a force measurement we typically use to control dynamics. We have developed two pad systems, one with 24 pads and a second with 2 arrays of 16 pads each. We emphasize the treatment of gestures as sub-sampled audio signals. This tight coupling of gesture with audio provides for a high degree of control intimacy. Our experiments with the pad arrays demonstrate that we can efficiently deal with large numbers of audio encoded gesture channels - 72 for the 24 pad array and 96 for the two 16 pad arrays.