gebhart/patrepeval huggingface dataset:
Modified zeolites. Part 1.—Dealuminated mordenites and their silanation (1978)

A series of partially dealuminated H-mordenites having different ratios SiO2/Al2O3 has been prepared from Na-mordenite by various treatments with acid. From these a series of dealuminated Na-mordenites has been made by treating the corresponding H-mordenites with dilute NaOH. The loss of water, including that from the groups [graphic omitted] and the “nests” of hydroxyls, H4O4, has been investigated as a function of temperature for the dealuminated forms. This showed at 360°C the existence of some OH groups not originating from [graphic omitted]. Such groups were attributed to —OH originating from nests. The silanation of the dealuminated H- and Na-mordenites was investigated quantitatively. In the mordenites free of zeolitic water the ratios H2(evolved)/SiH4(chemisorbed) were always between 1.5 and 2 and each ratio usually remained reasonably constant over the course of a run. This suggested a rather constant ratio of primary chemisorption to secondary reaction during many runs. The ratio increased above 2 only if zeolitic water was also present. No evidence was found for a significant amount of the reaction [graphic omitted] in which SiH4 interacts with intact “nests”, H4O4, to regenerate defect-free framework. The Elovich equation appeared able to represent the kinetics of chemisorption of SiH4.
Qualitative Adaptive Reward Learning With Success Failure Maps: Applied to Humanoid Robot Walking (2012)

In the human brain, rewards are encoded in a flexible and adaptive way after each novel stimulus. Neurons of the orbitofrontal cortex are the key reward structure of the brain. Neurobiological studies show that the anterior cingulate cortex of the brain is primarily responsible for avoiding repeated mistakes. According to vigilance threshold, which denotes the tolerance to risks, we can differentiate between a learning mechanism that takes risks and one that averts risks. The tolerance to risk plays an important role in such a learning mechanism. Results have shown the differences in learning capacity between risk-taking and risk-avert behaviors. These neurological properties provide promising inspirations for robot learning based on rewards. In this paper, we propose a learning mechanism that is able to learn from negative and positive feedback with reward coding adaptively. It is composed of two phases: evaluation and decision making. In the evaluation phase, we use a Kohonen self-organizing map technique to represent success and failure. Decision making is based on an early warning mechanism that enables avoiding repeating past mistakes. The behavior to risk is modulated in order to gain experiences for success and for failure. Success map is learned with adaptive reward that qualifies the learned task in order to optimize the efficiency. Our approach is presented with an implementation on the NAO humanoid robot, controlled by a bioinspired neural controller based on a central pattern generator. The learning system adapts the oscillation frequency and the motor neuron gain in pitch and roll in order to walk on flat and sloped terrain, and to switch between them.
Pathology of the Ear in the Cardio-Auditory Syndrome of Jervell and Lange-Nielsen (Recessive Deafness with Electrocardiographic Abnormalities) (1966)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Fast segmentation, tracking, and analysis of deformable objects (2002)

The authors present a physically based deformable model which can be used to track and analyze non-rigid motion of dynamic structures in time sequences of 2-D or 3-D medical images. The model considers an object undergoing an elastic deformation as a set of masses linked by springs, where the natural length of the springs is set equal to zero and is replaced by a set of constant equilibrium forces, which characterize the shape of the elastic structure in the absence of external forces. This model has the extremely nice property of yielding dynamic equations which are linear and decoupled for each coordinate, irrespective of the amplitude of the deformation. It provides a reduced algorithmic complexity, and a sound framework for modal analysis, which allows a compact representation of a general deformation by a reduced number of parameters. The power of the approach to segment, track and analyze 2-D and 3-D images is demonstrated by a set of experimental results on various complex medical images.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Laboratory Investigation of Hg Release from Flue Gas Desulfurization Products (2010)

Flue gas desulfurization (FGD) is a process applied to remove acid deposition precursors from the coal combustion air stream. This process also removes mercury (Hg) resulting in accumulation of this element in FGD produced solids. This project investigated Hg release from FGD materials to the air and water. Hg concentrations in the synthetic leaching precipitation procedure extracts, designed to simulate rainwater pH conditions, were in general <10 ng L(-1). Unlike coal fly ash, which has been found to adsorb Hg from the air, FGD materials were found to release Hg to the air over time with the addition of water a dominant environmental factor promoting release. The chemistry of the atmosphere to which the FGD materials were exposed (i.e., air Hg concentration and presence of oxidants), as well as that of the material (i.e., salts removed), was found to influence the magnitude of emissions. Although this work showed a component of the Hg captured by the FGD process could be released to the air under laboratory conditions, the potential for release under disposal and beneficial use conditions needs to be determined.
Pharmacotherapy of social phobia: an interim report of a placebo-controlled comparison of phenelzine and atenolol. (1988)

Forty-one patients meeting DSM-III criteria for social phobia completed a randomized comparative trial of the monoamine oxidase inhibitor phenelzine, the cardioselective beta-adrenergic blocker atenolol, and placebo. No significant differences were seen after 4 weeks of treatment in this preliminary trial. At the end of 8 weeks, however, phenelzine demonstrated greater efficacy than atenolol or placebo on dimensional ratings of overall severity of social phobia. No atenolol-placebo differences were observed. The authors shall present maintenance and discontinuation findings in a final report. Phenelzine may act in patients with social phobia by directly reducing interpersonal hypersensitivity.
Deriving the optimal structure of N-version software under resource requirements and cost/timing constraints (2002)

The paper presents an approach to systematically derive the optimal structure of fault-tolerant software for safety-critical control processes, with respect to resource requirements and cost- and timing constraints. For the modelling of the control process, a graph model description is used; basic static distributed scheduling and allocation decisions for the tasks are performed and task computation times are defined. Adaptive optimization techniques are used to derive the optimal solution for the given requirements. The application of the method in practice is illustrated by the example of a software system for spacecraft control.
MicroRNAs: Small RNAs With Big Effects (2010)

MicroRNAs (miRNAs) are evolutionarily conserved, small ( approximately 20-25 nucleotides), single-stranded molecules that suppress the expression of protein-coding genes by translational repression, messenger RNA degradation, or both. More than 700 miRNAs have been identified in the human genome. Amazingly, a single miRNA can regulate the expression of hundreds of mRNAs or proteins within a cell. The small RNAs are fast emerging as master regulators of innate and adaptive immunity and likely to play a pivotal role in transplantation. The clinical application of RNA sequencing ("next-generation sequencing") should facilitate transcriptome profiling at an unprecedented resolution. We provide an overview of miRNA biology and their hypothesized roles in transplantation.
Effects of Caffeine and Aspirin on Light Resistance Training Performance, Perceived Exertion, and Pain Perception (2008)

This study compared independent effects of caffeine and aspirin on muscular endurance (repetitions), heart rate (HR), perceived exertion (RPE), and perceived pain index (PPI) during light resistance training bouts performed to volitional failure. It was hypothesized that the hypoalgesic properties of these ergogenic aids would decrease pain perception and potentially result in enhanced performance. College-aged men (n = 15) participated in a within-subjects, double-blind study with three independent, counterbalanced sessions wherein aspirin (10 mg x kg(-1)), caffeine (6 mg x kg(-1)), or matched placebo were ingested 1 hour before exercise, and RPE, HR, PPI, and repetitions (per set and total per exercise) were recorded at 100% of individual, predetermined, 12-repetition maximum for leg extensions (LE) and seated arm curls (AC). Repeated-measures analyses of variance were used for between-trial comparisons. Caffeine resulted in significantly greater (p < 0.05) HR (LE and AC), total repetitions (LE), and repetitions in set 1 (LE and AC) compared with aspirin and placebo. Aspirin resulted in significantly higher PPI in set 1 (LE). In LE, 47% of participants' performance exceeded the predetermined effect size (>or= 5 repetitions) for total repetitions, with 53% exceeding the effect size (>or= 2 repetitions) for repetitions in set 1 with caffeine (vs. placebo). In AC, 53% (total repetitions) and 47% (set 1 repetitions) of participants exceeded effect sizes with caffeine (vs. placebo), with only 13% experiencing decrements in performance (total repetitions). Aspirin also produced a higher PPI and RPE overall and in set 1 (vs. placebo). This study demonstrates that caffeine significantly enhanced resistance training performance in LE and AC, whereas aspirin did not. Athletes may improve their resistance training performance by acute ingestion of caffeine. As with most ergogenic aids, our analyses indicate that individual responses vary greatly.
Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development (2001)

Vertebrate skeletogenesis requires a well-coordinated transition from chondrogenesis to osteogenesis. Hypertrophic chondrocytes in the growth plate play a pivotal role in this transition. Parathyroid hormone-related peptide (PTHrP), synthesized in the periarticular growth plate, regulates the site at which hypertrophy occurs. By comparing PTH/PTHrP receptor(-/-)/wild-type (PPR(-/-)/wild-type) chimeric mice with IHH(-/-);PPR(-/-)/wild-type chimeric and IHH(-/-)/wild-type chimeric mice, we provide in vivo evidence that Indian hedgehog (IHH), synthesized by prehypertrophic and hypertrophic chondrocytes, regulates the site of hypertrophic differentiation by signaling to the periarticular growth plate and also determines the site of bone collar formation in the adjacent perichondrium. By providing crucial local signals from prehypertrophic and hypertrophic chondrocytes to both chondrocytes and preosteoblasts, IHH couples chondrogenesis to osteogenesis in endochondral bone development.
Altered Hematopoiesis in Murine Sickle Cell Disease (1999)

We investigated the mechanisms of sickle cell disease (SCD) hematopoietic/erythropoietic defects using bone marrow, spleen, and/or peripheral blood from the transgenic SAD mouse model, which closely reproduces the biochemical and physiological disorders observed in human SCD. First, the erythropoietic lineage late precursors (polychromatophilic normoblasts to the intramedullary reticulocytes) of SAD mouse bone marrow were significantly altered morphologically. These anomalies resulted from high levels of hemoglobin polymers and were associated with increased cell fragmentation occurring during medullary endothelial migration of reticulocytes. Secondly, analysis of bone marrow erythropoiesis in earlier stages showed a marked depletion in SAD erythroid burst-forming units (BFU-E; of approximately 42%) and erythroid colony-forming units (CFU-E; of approximately 23%) progenitors, despite a significant increase in their proliferation, suggesting a compensatory mechanism. In contrast to the bone marrow progenitor depletion, we observed (1) a high mobilization/relocation of BFU-E early progenitors (approximately 4-fold increase) in peripheral blood of SAD mice as well as of colony-forming units-granulocyte-macrophage (CFU-GM) and (2) a 7-fold increase of SAD CFU-E in the spleen. Third, and most importantly, SAD bone marrow multipotent cells (spleen colony-forming units [CFU-S], granulocyte-erythroid-macrophage-megakaryocyte colony-forming units [CFU-GEMM], and Sca(+)Lin(-)) were highly mobilized to the peripheral blood (approximately 4-fold increase), suggesting that peripheral multipotent cells could serve as proliferative and autologous vehicles for gene therapy. Therefore, we conclude the following. (1) The abnormal differentiation and morphology of late nucleated erythroid precursors result in an ineffective sickle erythropoiesis and likely contribute to the pathophysiology of sickle cell disorders; this suggests that transfer of normal or modified SCD bone marrow cells may have a selective advantage in vivo. (2) A hematopoietic compensatory mechanism exists in SAD/SCD pathology and consists of mobilization of multipotent cells from the bone marrow to the peripheral blood and their subsequent uptake into the spleen, an extramedullary hematopoietic site for immediate differentiation. Altogether, these results corroborate the strong potential effectiveness of both autologous and allogeneic bone marrow transplantation for SCD hematopoietic therapy.
AIE luminogen bridged hollow hydroxyapatite nanocapsules for drug delivery (2013)

A new type of organophosphonic acid, (4,4'-(1,2-diphenylethene-1,2-diyl)bis(4,1-phenylene))bis(methylene)diphosphonic acid (PATPE), based on tetraphenylethene has been prepared, and its ester derivative exhibits the characteristic property of aggregation-induced emission (AIE) in DMSO-H2O solution. The PATPE is then fabricated into hydroxyapatite by a one-pot condensation process to form hollow mesoporous nanocapsules of ellipsoidal morphology. The AIE luminogen-bridged hollow hydroxyapatite nanocapsules emit strong blue light under UV irradiation, which is further used for drug delivery using ibuprofen (IBU) as a model drug. The fluorescence intensity of the materials varies greatly with the loading and release of IBU, suggesting that the drug release process may be tracked in terms of the change of luminescence intensity. The biocompatibility of AIE luminogen functionalized material is also evaluated on HUH7 human hepatoma cells using the MTT assay. The low cytotoxicity of the materials reveals that the as-prepared multifunctional hydroxyapatite will be a new candidate for simultaneous drug delivery and cell imaging in potential bioapplications.
Direct absolute quantification of metabolites in the human brain with <i>in vivo</i> localized proton spectroscopy (1992)

The absolute concentrations of the three major brain metabolites observable by in vivo proton spectroscopy--N-acetylaspartate(NAA), creatine and phosphocreatine (Cr and PCr) and choline (Cho)--have been measured at four standardized localizations in 34 healthy volunteers by in vivo localized proton spectroscopy using an external reference sample. The results show that the concentration of Cr and PCr as observed by in vivo MRS (5-6 mmol/L) is lower than that measured by other methods. The results are concordant with the hypothesis, that the Cr and PCr resonance as observed by proton spectroscopy is due mainly to PCr, whereas Cr remains invisible by being attached to a larger molecule. It is also demonstrated, that Cr and PCr is higher in the cerebellum than in the cerebrum, whereas NAA remains constant within the margin of error (8-9 mmol/L).
Security-Constrained Unit Commitment With AC Constraints* (2005)

In a restructured power market, the independent system operator (ISO) executes the security-constrained unit commitment (SCUC) program to plan a secure and economical hourly generation schedule for the day-ahead market. This paper introduces an efficient SCUC approach with ac constraints that obtains the minimum system operating cost while maintaining the security of power systems. The proposed approach applies the Benders decomposition for separating the unit commitment (UC) in the master problem from the network security check in subproblems. The master problem applies the augmented Lagrangian relaxation (LR) method and dynamic programming (DP) to solve UC. The subproblem checks ac network security constraints for the UC solution to determine whether a converged and secure ac power flow can be obtained. If any network violations arise, corresponding Benders cuts will be formed and added to the master problem for solving the next iteration of UC. The iterative process will continue until ac violations are eliminated and a converged optimal solution is found. In this paper, a six-bus system and the IEEE 118-bus system with 54 units are analyzed to exhibit the effectiveness of the proposed approach.
Hierarchically Structured Hole Transport Layers of Spiro‐OMeTAD and Multiwalled Carbon Nanotubes for Perovskite Solar Cells (2015)

The low electrical conductivity of spiro-OMeTAD hole transport layers impedes further enhancements of the power conversion efficiency (PCE) of perovskite solar cells. We embedded multiwalled carbon nanotubes (MWNTs) in spiro-OMeTAD (spiro-OMeTAD/MWNTs) to increase carrier mobility and conductivity. However, direct electrical contact between CH3 NH3 PbI3 and the MWNTs created pathways for undesirable back-electron transfer, owing to the large work function of MWNTs, limiting enhancements of the PCE. A hierarchical structure of pure spiro-OMeTAD and spiro-OMeTAD/MWNTs was designed to block back-electron transfer and fully exploit the enhanced charge transport of spiro-OMeTAD/MWNTs. The enhanced fill factor, short-circuit current density, open-circuit voltage, and PCE (15.1 %) were achieved by using this hierarchical hole transport layer structure (MWNT concentration=2 wt %). The perovskite solar cells were fabricated by a low-temperature solution process, further decreasing their per-Watt cost.
High Efficiency, Low Emissions RCCI Combustion by Use of a Fuel Additive (2010)

<div class="section abstract"><div class="htmlview paragraph">Heavy-duty engine experiments were conducted to explore reactivity controlled compression ignition (RCCI) combustion through addition of the cetane improver di-tert-butyl peroxide (DTBP) to pump gasoline. Unlike previous diesel/gasoline dual-fuel operation of RCCI combustion, the present study investigates the feasibility of using a single fuel stock (gasoline) as the basis for both high reactivity and low reactivity fuels. The strategy consisted of port fuel injection of gasoline and direct injection of the same gasoline doped with a small volume percent addition of DTBP. With 1.75% DTBP by volume added to only the direct-injected fuel (which accounts for approximately 0.2% of the total fueling) it was found that the additized gasoline behaved similarly to diesel fuel, allowing for efficient RCCI combustion. The single fuel results with DTBP were compared to previous high-thermal efficiency, low-emissions results with port injection of gasoline and direct injections of diesel. The comparison between fueling strategies found that the higher volatility of gasoline enabled a reduction in the direct injection pressure from 800 (bar) with diesel to 400 (bar) with gasoline. At the tested conditions, the peak gross indicated based thermal efficiency was over 57%. The emissions trends and magnitudes of the single fuel strategy were also comparable to those of the diesel/gasoline dual-fuel strategy, and both engine-out NO<sub>X</sub> and PM met EPA HD 2010 emissions mandates without aftertreatment. Also, the decreased low temperature heat release with the single fuel strategy was found to lower compression work and increased thermal efficiency by approximately 1% over the diesel/gasoline case. The results demonstrate that a very small percentage of an appropriate additive can be used to establish a sufficiency large reactivity gradient to match the performance of a dual fuel strategy when operated in the RCCI combustion regime.</div></div>
ASIP design methodologies: survey and issues (2002)

Interest in synthesis of Application Specific Instruction Processors or ASIPs has increased considerably and a number of methodologies have been proposed in the last decade. This paper attempts to survey the state of the art in this area and identifies some issues which need to be addressed. We have identified the five key steps in ASIP design as application analysis, architectural design space exploration, instruction set generation, code synthesis and hardware synthesis. A broad classification of the approaches reported in the literature is done. The paper notes the need to broaden the architectural space being explored and to tightly couple the various subtasks in ASIP synthesis.
Power-and-area efficient 14-bit 1.5 MSample/s two-stage algorithmic ADC based on a mismatch-insensitive MDAC (2008)

This paper presents a 14-bit 1.5 MSample/s two-stage algorithmic ADC with a power-and-area efficiency better than 0.5 pJmm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> per conversion. This competes with the most efficient architectures available today namely, ΣΔ and self-calibrated pipeline. The 2 stages of the ADC are based on a new 1.5-bit mismatch-insensitive MDAC and simulations demonstrate that a THD of −79 dB and an ENOB better than 12 bits can be reached without self-calibration.
The pale evidence for treatment of iron-deficiency anaemia in older people (2018)

Funding The authors have received funding to carry out a pilot RCT on management of IDA in older people from the Chief Scientist Office, Scotland.
Intestinal complications of radiotherapy in gynecologic malignancy — clinical presentation and management (1995)

Radiation therapy is an effective treatment modality for various gynecologic malignancies. In spite of advances in radiotherapy equipment and techniques over the years, the gastrointestinal and urinary tracts have remained a considerable problem with radiotherapy of the pelvis and abdomen. Clinical presentation of intestinal complications, current concepts of pathophysiology and principles of medical and surgical management are reviewed.
Determination of Dominant-Yield-Loss Mechanism with Volume Diagnosis (2009)

The cost and cycle time for determining the root cause of yield loss continues to increase as semiconductor technology scales down. A new technique, Axiom, helps yield and product engineers determine the root cause of loss directly from diagnosis results. Consequently, root-cause cycle time is dramatically reduced, resulting in a higher physical-failure analysis success rate and reduced costs.
An Analysis of the Effect on Using Digital Exhibition of Archives (2013)

정보화 사회의 도래로 아카이브 기관은 대국민 서비스의 일환으로 디지털 기술을 도입하여 보존과 전시에 활용하기에 이르렀다. 본 연구의 목적은 급변하는 기술의 발전으로 인하여 아카이브 전시에 다양한 디지털 기술을 사용하는 것에 대한 필요성을 고찰하는 것이다. 이를 위해 아카이브와 디지털 전시의 개념과 유형을 살펴보고, 아카이브에 디지털 전시방법을 사용할 때 그 활용도를 조사하였다. 또한 구체적인 기록물관리기관의 디지털 전시사례를 조사하였다. 아카이브자료를 웹페이지를 통하여 전시했을 때 가장 큰 장점은 기록물이 가지는 본연의 정보 제공의 기능과 더불어 하이퍼링크 기술을 통한 정보의 무한 확장성을 들 수 있다. 디지털전시의 방법으로 가상현실은 평면적인 아카이브에 입체감과 현실감을 넣어 이용자의 흥미와 관심을 불러일으킨다. 또한 스토리텔링은 온라인상에 이용자와의 커뮤니케이션의 장을 만들어 서로 상호작용을 하며 이 과정까지도 스토리에 반영되어 새로운 콘텐츠로 탄생된다. 이러한 일련의 기능들이 아카이브에 대한 관심과 흥미를 높여 이용자들의 정보의 공유, 참여를 가져오고, 더불어 디지털 전시를 통한 새로운 콘텐츠 자원은 문화 자원과 관광 자원으로 지역사회와 기관을 홍보하므로 아카이브 전시에 다양한 디지털 기술을 사용하는 것은 그 의의가 있다.