gebhart/patrepeval huggingface dataset:
The dominant flocculation genes of <i>Saccharomyces cerevisiae</i> constitute a new subtelomeric gene family (1995)

The quality of brewing strains is, in large part, determined by their flocculation properties. By classical genetics, several dominant, semidominant and recessive flocculation genes have been recognized. Recent results of experiments to localize the flocculation genes FLO5 and FLO8, combined with the in silicio analysis of the available sequence data of the yeast genome, have revealed that the flocculation genes belong to a family which comprises at least four genes and three pseudogenes. All members of this gene family are located near the end of chromosomes, just like the SUC, MEL and MAL genes, which are also important for good quality baking or brewing strains. Transcription of the flocculation genes is repressed by several regulatory genes. In addition, a number of genes have been found which cause cell aggregation upon disruption or overexpression in an as yet unknown manner. In total, 33 genes have been reported that are involved in flocculation or cell aggregation.
Ribonuclease P (2011)

The gene coding for the RNA subunit of ribonuclease P (RNase P) is essential in all free-living organisms. The RNA subunit, itself, is an enzyme and, from its evolutionary tree, we can infer that it is a very ancient molecule. The specificity of this enzyme is that it cleaves other RNA molecules at the junction of single-stranded and the 5' end of double-stranded regions of RNA. One can speculate that this molecule was very useful in an ancient world in cleaving long pieces of RNA, which must have contained hairpin regions in it, into shorter molecules with the capability of different functions from the longer parent. Today, the specificity of the enzyme can be used in designing drug therapies.
A runtime adaptive controller for supporting hardware components with variable latency (2011)

Nowadays, the design of hardware cores has to necessarily deal with unpredictable components, due to process variation or to the interaction with external modules (e.g., memories, sensors, IP cores). Adaptive systems are, thus, one of the most important solutions to substitute traditional approaches, based on analysis at design time, especially in critical environments. In this paper, we present an innovative lightweight controller architecture able to automatically adjust its behavior at run-time. It interacts with the surrounding environment by means of a simple token-based communication schema. We examine the capabilities of the proposed architectural model to adapt its behavior during the execution, compared to classical ones, such as the finite state machine.
Suppression of IgE responses in inbred rats by repeated respiratory tract exposure to antigen: Responder phenotype influences isotype specificity of induced tolerance (1984)

Repeated exposure of rats to an aerosol of ovalbumin (OVA) induced tolerance to subsequent parenteral challenge with the same antigen. In the low-IgE responder WAG strain, responses in both the IgE and IgG classes were affected, whereas rats of the moderate (Lou/M) and high-IgE responder BN strain developed high titers of anti-OVA IgG in serum during exposure with concomitant tolerance in the IgE class. Repeated parenteral challenge, however, failed to elicit significant secondary anti-OVA IgG responses in the Lou/M and BN strains, suggesting that the isotype specificity of induced tolerance in these strains was not absolute. Spleen and respiratory tract lymph node cells, but not serum from aerosol-exposed BN rats, were capable of transferring IgE isotype- and antigen-specific tolerance. Dose response experiments demonstrated that the low-IgE responder WAG strain was exquisitely sensitive to tolerance induction in response to antigen inhalation, being susceptible to dosages in the nanogram range; at least 1000 times more antigen was required in the high-IgE responder BN to induce comparable tolerance in the IgE class. It was also apparent that the IgE isotype was more readily suppressed than the IgG isotype in both high- and low-IgE responder strains.
Wireless Network Information Flow: A Deterministic Approach (2011)

In a wireless network with a single source and a single destination and an arbitrary number of relay nodes, what is the maximum rate of information flow achievable? We make progress on this long standing problem through a two-step approach. First, we propose a deterministic channel model which captures the key wireless properties of signal strength, broadcast and superposition. We obtain an exact characterization of the capacity of a network with nodes connected by such deterministic channels. This result is a natural generalization of the celebrated max-flow min-cut theorem for wired networks. Second, we use the insights obtained from the deterministic analysis to design a new quantize-map-and-forward scheme for Gaussian networks. In this scheme, each relay quantizes the received signal at the noise level and maps it to a random Gaussian codeword for forwarding, and the final destination decodes the source's message based on the received signal. We show that, in contrast to existing schemes, this scheme can achieve the cut-set upper bound to within a gap which is independent of the channel parameters. In the case of the relay channel with a single relay as well as the two-relay Gaussian diamond network, the gap is 1 bit/s/Hz. Moreover, the scheme is universal in the sense that the relays need no knowledge of the values of the channel parameters to (approximately) achieve the rate supportable by the network. We also present extensions of the results to multicast networks, half-duplex networks, and ergodic networks.
<title>Optomechanical microprobe system for measuring very small parts on CMMs</title> (1998)

An opto-mechanical microprobe system which combines the advantages of optical non-contact method and mechanical contact one is proposed for measuring very small parts on coordinate measuring machines. The principle is based on the evaluation of a central position of stylus ball by an optical system, the stylus ball is illuminated by a cold light source through an optical fiber. The most inventive advantage of the microprobe is that the deformation of its stylus does not influence the measuring results, so the stylus could be extremely thin. Until now an opto-mechanical microprobe with stylus ball of diameter of about 40 micrometers and stylus of diameter of about 20 micrometers is developed. Experiments show that the accuracy of the opto-mechanical microprobe is better than 1 micrometers and the measuring force is less than 10 (mu) N.
Characterization of GMR Nonlinear Response and the Impact on BER in Perpendicular Magnetic Recording (2004)

The giant magnetoresistive (GMR) reader nonlinear response in perpendicular magnetic recording should be characterized and studied for the impact on bit-error-rate (BER) performance, because a waveform of perpendicular recording is influenced by GMR nonlinearity differently from longitudinal recording. In this study, the read/write characteristics and BER performance under the influence of GMR nonlinearity were investigated. For a GMR saturation parameter, the amplitude ratio of the fifth harmonic spectrum of isolated patterns to same spectrum of di-bit pattern was measured. This saturation parameter is a good indicator to estimate GMR saturation. GMR asymmetry has a different impact on BER performance from GMR saturation. The raw isolated waveform of perpendicular recording is inappropriate to estimate GMR asymmetry because it does not indicate an accurate dc-ground level with the low-frequency cutoff channel. A specific test patterns which can provide dc-ground level, was found. The measured asymmetry of this test pattern correlates closely with the asymmetry of measured GMR transfer curves. The peak shift of a differential waveform is also a good indicator to estimate GMR asymmetry. Signal processing simulation and some measurement results showed BER performance is influenced by GMR nonlinear response. The impact of GMR nonlinearity on BER depends on their feature. GMR asymmetry has a strong correlation with BER performance.
Regional Cerebral Blood Flow in the Amygdala and Medial PrefrontalCortex During Traumatic Imagery in Male and Female Vietnam Veterans With PTSD (2004)

These results suggest a reciprocal relationship between medial prefrontal cortex and amygdala function in PTSD and opposing associations between activity in these regions and symptom severity consistent with current functional neuroanatomic models of this disorder.
Crystal Structure of a Mutant hERα Ligand-binding Domain Reveals Key Structural Features for the Mechanism of Partial Agonism (2001)

The crystal structure of a triple cysteine to serine mutant ERalpha ligand-binding domain (LBD), complexed with estradiol, shows that despite the presence of a tightly bound agonist ligand, the protein exhibits an antagonist-like conformation, similar to that observed in raloxifen and 4-hydroxytamoxifen-bound structures. This mutated receptor binds estradiol with wild type affinity and displays transcriptional activity upon estradiol stimulation, but with limited potency (about 50%). This partial activity is efficiently repressed in antagonist competition assays. The comparison with available LBD structures reveals key features governing the positioning of helix H12 and highlights the importance of cysteine residues in promoting an active conformation. Furthermore the present study reveals a hydrogen bond network connecting ligand binding to protein trans conformation. These observations support a dynamic view of H12 positioning, where the control of the equilibrium between two stable locations determines the partial agonist character of a given ligand.
Effects of Ionizing Energy and Ozone Treatments on the Microbial Decontamination and Physicochemical Properties of Aloe Powders and Bee Pollen (1997)

The comparative effects of gamma irradiation and ozone treatment on the microbiological and physicochemical qualities were investigated for the improvement of hygienic quality of aloe powder and bee pollen. Gamma irradiation at 7.5~10kGy could reduce total aerobic bacteria, molds and coliforms below detection levels, but ozone treatment up to 18ppm for 8hr was not sufficient to eliminate the microorganisms from aloe powder and bee pollen. The physicochemical properties such as fatty acid and amino acid compositions, mineral content, TBA value, barbaloin and pigment contents were not significantly changed by gamma irradiation, whereas ozone treatment caused significant changes in fatty acid composition, lipid oxidation and destruction of barbaloin and natural pigments.
Treatment of Metal-Contaminated Water Using Bacterial Sulfate Reduction: Results from Pilot-Scale Reactors (1991)

Simple anaerobic reactors were installed to treat metal-contaminated water in an underground coal mine and at a smelting residues dump in Pennsylvania. The reactors consisted of barrels and tanks filled with spent mushroom compost, within which bacterial sulfate reduction became established. Concentrations of Al, Cd, Fe, Mn, Ni, and Zn were typically lowered by over 95% as contaminated water flowed through the reactors. Cadmium, Fe, Ni, and some Zn were retained as insoluble metal sulfides following their reaction with bacterially generated H2S. Aluminum, Mn, and some Zn hydrolyzed and were retained as insoluble hydroxides or carbonates. Reactor effluents were typically circumneutral in pH and contained net alkalinity. The principal sources of alkalinity in the reactors were bacterial sulfate reduction and limestone dissolution. This article examines the chemistry of the reactor systems and the opportunities for enhancing their metal-retaining and alkalinity-generating potential. © 1992 John Wiley & Sons, Inc.
Development of a microphotocantilever for near-field scanning optical microscopy (2005)

A new type of near-field scanning optical microscopy (NSOM) using a microcantilever with a photo diode on its tip is described. The photo-sensitive cantilever, c alled a microphotocantil ever, was fabricated using micromachining techniques and its use demonstrated. Fine NSOM images below 20 nm are obtained. Atomic force microscopy (AFM) c an be done simultaneously to NSOM using t he microphotocantilever. Well correlated NSOM and AFM images are obtained in the near-field optical mode.
Cross-resonant optical parametric oscillators: study of and application to difference-frequency generation (2005)

We revisit both theoretically and experimentally the study of a two-crystal optical parametric oscillator (OPO) for which the signal and the idler beams are totally and exclusively output coupled after the first and the second crystals, respectively. This geometry, referred as cross-resonant OPO, is useful for applications that require the production of two beams that can be independently adjusted. A theoretical analysis is carried out by use of a plane-wave semianalytical rate-equation approach that completely includes pump depletion and reconstruction effects. We also report on an experimental investigation of a 1.064 µm pump-pulsed KTP cross-resonant OPO whose performance is compared with that of a singly resonant OPO with a similar oscillation threshold. To illustrate the practical advantages of such a configuration, we performed difference-frequency generation in a CdSe crystal by mixing the signal and idler beams of the cross-resonant OPO to produce mid-infrared radiation over the 8-12 µm range.
Performance of meshed comb constellations for minimizing target revisit time (2002)

Walker satellite constellations are commonly proposed for remote sensing applications requiring global access. However, for many applications, target revisit time may be as important as coverage area. A subclass of non-Walker constellations called "meshed comb" constellations can outperform most Walker constellations in coverage and/or revisit time in many situations. Exhaustive comparisons were made of an eight-satellite meshed comb constellation with a variety of eight-satellite Walker constellations against several types of target decks. The results showed that the meshed comb constellation typically had the lowest maximum revisit time; and the average revisit time was comparable to or better than any of the Walker constellations. In addition, the meshed comb constellation usually had the lowest standard deviation for revisit time, as well as the lowest 2/spl sigma/ and 3/spl sigma/ revisit times.
Controlled Anionic Polymerization of <i>tert</i>-Butyl Acrylate with Diphenylmethylpotassium in the Presence of Triethylborane (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTControlled Anionic Polymerization of tert-Butyl Acrylate with Diphenylmethylpotassium in the Presence of TriethylboraneTakashi Ishizone, Ken Yoshimura, Eriko Yanase, and Seiichi NakahamaView Author Information Department of Polymer Chemistry, Faculty of Engineering, Tokyo Institute of Technology, 2-12-1, Ohokayama, Meguro-ku, Tokyo 152-8552, Japan Cite this: Macromolecules 1999, 32, 3, 955–957Publication Date (Web):January 21, 1999Publication History Received14 August 1998Revised25 November 1998Published online21 January 1999Published inissue 1 February 1999https://pubs.acs.org/doi/10.1021/ma9812884https://doi.org/10.1021/ma9812884rapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views470Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Additives,Anionic polymerization,Organic compounds,Polymerization,Polymers Get e-Alerts
Donor Dominance Cures CHILD Nevus (2010)

The favorable outcome, superior to that obtained by simple dermabrasion or extensive plastic surgery, can best be explained by the donor dominance of the grafted skin samples that carried, in all or most cells, the mutant X chromosome in an inactivated form.
Structure–Activity Relationships of Phenylalkylamines as Agonist Ligands for 5‐HT<sub>2A</sub> Receptors (2008)

Agonist activation of central 5-HT(2A) receptors results in diverse effects, such as hallucinations and changes of consciousness. Recent findings indicate that activation of the 5-HT(2A) receptor also leads to interesting physiological responses, possibly holding therapeutic value. Selective agonists are needed to study the full therapeutic potential of this receptor. 5-HT(2A) ligands with agonist profiles are primarily derived from phenylalkylamines, indolealkylamines, and certain piperazines. Of these, phenylalkylamines, most notably substituted phenylisopropylamines, are considered the most selective agonists for 5-HT(2) receptors. This review summarizes the structure-activity relationships (SAR) of phenylalkylamines as agonist ligands for 5-HT(2A) receptors. Selectivity is a central theme, as is selectivity for the 5-HT(2A) receptor and for its specific signaling pathways. SAR data from receptor affinity studies, functional assays, behavioral drug discrimination as well as human studies are discussed.
Improved selective properties of SiO{sub 2}/TiN{sub x}O{sub y}-Al tandem absorbers effected by tempering (1994)

TiN{sub x}O{sub y}-Al and SiO{sub 2}/TiN{sub x}O{sub y}-Al selective absorbers, prepared in an ARE (Activated Reactive Evaporation) deposition process, have been investigated in respect of effects induced by heat treatment. Samples were exposed to residual gas atmospheres of 10{sup {minus}4} hPa and 10hPa respectively, in a temperature range of 225 C--470 C. Three different processes were observed. They were analyzed investigating optical properties, element concentration and structure of the compounds. Reflectance measurements are in agreement with calculations of the spectral reflection from known optical constants.
Complex Hydrides for Hydrogen Storage (2003)

This report describes research into the use of complex hydrides for hydrogen storage. The synthesis of a number of alanates, (AIH4) compounds, was investigated. Both wet chemical and mechano-chemical methods were studied.
Some Advanced Techniques in Reducing Time for Path Planning Based on Visibility Graph (2011)

This paper describes some techniques based on polygon aggregation in reducing time for visibility graph in case of many obstacles. In path planning, the approaches are commonly used such as search-based, sampling-based or combinatorial planning. And visibility graph is one of the roadmaps of combinatorial planning. Building a visibility graph is a main phase in the whole process and theoretically it takes θ(nlogn). However, with some practical applications, for example one which has a large number of obstacles, this phase is very time-consuming. With the techniques proposed, the experiment result shows that the computing time gets a reduction factor of one-third approximately when the aggregation are used in preprocessing of building visibility graph.
Selfstarting passively mode-locked fibre ring soliton laser exploiting nonlinear polarisation rotation (1992)

Nonlinear birefringence effects in a fibre ring laser cavity have been exploited to produce selfstarting, passive mode-locking to give 1.5 ps soliton pulses.
Biochemical Characterization of the Kinase Domain of the Rice Disease Resistance Receptor-like Kinase XA21 (2002)

The rice disease resistance gene, Xa21, encodes a receptor kinase-like protein consisting of leucine-rich repeats in the putative extracellular domain and a serine/threonine kinase in the putative intracellular domain. The putative XA21 kinase domain was expressed as maltose-binding and glutathione S-transferase fusion proteins in Escherichia coli. The fusion proteins are capable of autophosphorylation. Phosphoamino acid analysis of the glutathione S-transferase fusion protein indicates that only serine and threonine residues are phosphorylated. The relative phosphorylation rate of the XA21 kinase against increasing enzyme concentrations follows a first-order rather than second-order kinetics, indicating an intramolecular phosphorylation mechanism. Moreover, the active XA21 kinase cannot phosphorylate a kinase-deficient mutant of XA21 kinase. The enzymatic activity of the XA21 kinase in a buffer containing Mn(2+) is at least 15 times higher than that with Mg(2+). The K(m) and V(max) of XA21 kinase for ATP are 0.3 microm and 8.4 nmol/mg/min, respectively. Tryptic phosphopeptide mapping reveals that multiple sites on the XA21 kinase are phosphorylated. Finally, our data suggest that the region of XA21 kinase corresponding to the RD kinase activation domain is not phosphorylated, revealing a distinct mode of action compared with the tomato Pto serine/threonine kinase conferring disease resistance.
A PRACTICAL TOOL FOR MASS-CUSTOMISING CONFIGURABLE PRODUCTS (2003)

Serum from 21 patients with lymphoblastic leukemia, five with myeloblastic leukemia and 30 age matched control subjects tested for thymic hormone activity in an assay that measures the induction of T cell surface antigen. This activity was subnormal in serum from 10 of 16 patients with untreated lymphoblastic leukemia (p less than 0.001) but was within the normal range when the leukemia was in remission. Low inductive activity was associated with an inhibitor of T cell induction which was less than 30,000 daltons in molecular size and interfered with induction by purified thymopoietin plus a high concentration of ubiquitin or by normal serum alone.
Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant: Further Clarifications (1991)

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