gebhart/patrepeval huggingface dataset:
A new family of omnidirectional and holonomic wheeled platforms for mobile robots (1994)

This paper presents the concepts for a new family of holonomic wheeled platforms that feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the "orthogonal-wheels" concept and the two major wheel assemblies on which these platforms are based. The authors then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. Several alternative designs are considered, and their respective characteristics with respect to rotational and translational motion control are discussed. The design and control of a prototype platform developed to test and demonstrate the proposed concepts is then described, and experimental results illustrating the full omnidirectionality of the platform with decoupled rotational and translational degrees of freedom are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Sappi announces its African Printers of 2010 : industry news (2010)

The 2010 Sappi African Printers of the Year were announced at a glittering gala event held at Sun City on 12 August. Evening dresses and bow ties were out in force as the who's who of the printing industry descended on Sun City for a night that featured all of the elements of a successful event - good food, good wine, good entertainment and excellent company. Added to this was the excitement of finding out who had won a sought-after gold, silver or bronze Sappi African Printers of the Year award. These highly prized awards recognise and reward the achievements of the best printers in the African region.
Sulfur Dioxide Insertion. III. The Synthesis and Characterization of π-Cyclopentadienyliron S-Sulfinatodicarbonyl Complexes<sup>1</sup> (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSulfur Dioxide Insertion. III. The Synthesis and Characterization of π-Cyclopentadienyliron S-Sulfinatodicarbonyl Complexes1Jane P. Bibler and Andrew WojcickiCite this: J. Am. Chem. Soc. 1966, 88, 21, 4862–4870Publication Date (Print):November 1, 1966Publication History Published online1 May 2002Published inissue 1 November 1966https://pubs.acs.org/doi/10.1021/ja00973a020https://doi.org/10.1021/ja00973a020research-articleACS PublicationsRequest reuse permissionsArticle Views276Altmetric-Citations98LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Room‐Temperature Organometallic Synthesis of Soluble and Crystalline ZnO Nanoparticles of Controlled Size and Shape (2003)

Nanomaterials made easy! The facile oxidation of [Zn(c-C6H11)2] at room temperature in an organic solvent containing long-chain amine ligands leads to the formation of size- and shape-controlled crystalline ZnO nanoparticles (see picture). These particles, in the form of nanodisks and nanorods of low size dispersity in the 3–10 nm size range, are fully soluble in organic solvents (e.g., THF) and photoluminescent.
Abl Family Kinases Regulate FcγR-Mediated Phagocytosis in Murine Macrophages (2012)

Phagocytosis of Ab-coated pathogens is mediated through FcγRs, which activate intracellular signaling pathways to drive actin cytoskeletal rearrangements. Abl and Arg define a family of nonreceptor tyrosine kinases that regulate actin-dependent processes in a variety of cell types, including those important in the adaptive immune response. Using pharmacological inhibition as well as dominant negative and knockout approaches, we demonstrate a role for the Abl family kinases in phagocytosis by macrophages and define a mechanism whereby Abl kinases regulate this process. Bone marrow-derived macrophages from mice lacking Abl and Arg kinases exhibit inefficient phagocytosis of sheep erythrocytes and zymosan particles. Treatment with the Abl kinase inhibitors imatinib and GNF-2 or overexpression of kinase-inactive forms of the Abl family kinases also impairs particle internalization in murine macrophages, indicating Abl kinase activity is required for efficient phagocytosis. Further, Arg kinase is present at the phagocytic cup, and Abl family kinases are activated by FcγR engagement. The regulation of phagocytosis by Abl family kinases is mediated in part by the spleen tyrosine kinase (Syk). Loss of Abl and Arg expression or treatment with Abl inhibitors reduced Syk phosphorylation in response to FcγR ligation. The link between Abl family kinases and Syk may be direct, as purified Arg kinase phosphorylates Syk in vitro. Further, overexpression of membrane-targeted Syk in cells treated with Abl kinase inhibitors partially rescues the impairment in phagocytosis. Together, these findings reveal that Abl family kinases control the efficiency of phagocytosis in part through the regulation of Syk function.
Bony Ingrowth Fixation of the Acetabular Component in Canine Hip Joint Arthroplasty (1983)

Five mature dogs were studied five to eight months after insertion of a newly designed acetabular component that eliminates the use of bone cement in total hip arthroplasty (THA). The component was hemispheric, with a layer of porous metal on its outside surface. It initially was fixed to the innominate bone by screws passed through projections from the edge of the metal substrate. When the dogs were killed five or eight months after implantation, all components were fixed rigidly to the bone. Bony ingrowth covered an average of 53% of the porous surface of the implant, penetrating three layers of balls.
Insulin Resistance and Endothelial Dysfunction Constitute a Common Therapeutic Target in Cardiometabolic Disorders (2016)

Insulin resistance and other risk factors for atherosclerosis, such as hypertension and hypercholesterolemia, promote endothelial dysfunction and lead to development of metabolic syndrome which constitutes an introduction to cardiovascular disease. The insulin resistance and endothelial dysfunction cross talk between each other by numerous metabolic pathways. Hence, targeting one of these pathologies with pleiotropic treatment exerts beneficial effect on another one. Combined and expletive treatment of hypertension, lipid disorders, and insulin resistance with nonpharmacological interventions and conventional pharmacotherapy may inhibit the transformation of metabolic disturbances to fully developed cardiovascular disease. This paper summarises the common therapeutic targets for insulin resistance, endothelial dysfunction, and vascular inflammatory reaction at molecular level and analyses the potential pleiotropic effects of drugs used currently in management of cardiovascular disease, metabolic syndrome, and diabetes.
ALPHA-a high-performance LISP machine equipped with a new stack structure and garbage collection system (1983)

ALPHA is a dedicated machine designed for high-speed list processing. In this article, we describe a highly effective stack which can support a value cache and virtual stack, and high-speed garbage collection algorithm for virtual memory. These new ideas have been studied in ALPHA. ALPHA is designed as a back end processor for a large computer under TSS. ALPHA allows TSS users to do more high-speed list processing than a large computer does.
The vibration analysis of drive shaft based on SolidWorks (2011)

In order to reduce the vibration and prevent the resonance efficiently, the vibration character of drive shaft of car has been analyzed by finite element analysis method with SolidWorks software in this paper. Firstly, the model of drive shaft has been established and divided into a certain number of units by means of Simulation plug-ins. Secondly, the three vibration modes, the corresponding displacement and vibration frequency were obtained after the finite element model of drive shaft was calculated and analyzed by the computer. Finally, based on the vibration frequency that had been obtained, the engine speed was calculated which was correspond to the critical speed and the natural frequency of the shaft. Then, we could prevent the resonance of the drive shaft by way of keeping away from the resonance speed range of the shaft when we designed to match the engine and power train. This research method provided a basis for engineers who engaged in mechanical vibration characteristics matching of the vehicles transmission.
Design of compact dual‐passband LTCC filter exploiting stacked QMSIW and EMSIW (2015)

A dual‐passband low‐temperature co‐fired ceramic (LTCC) filter with a stacked quarter‐mode substrate‐integrated waveguide (QMSIW) and an eighth‐mode SIW (EMSIW) on LTCC substrates is presented. By exploiting the QMSIW and EMSIW cavities, the filter has a dual passband with high selectivity and compact size. The experimental filter exhibits two passbands, one is centred at 5.4 GHz with an insertion loss of <1.7 dB, and a 3 dB bandwidth of 13%. The other is centred at 8.3 GHz with an insertion loss of <1.5 dB, and with a bandwidth of 12.9%. The volume of the filter is only 6.5 × 6.5 × 1.2 mm 3 .
<i>Sonic hedgehog</i> is not required for the induction of medial floor plate cells in the zebrafish (1998)

Sonic hedgehog (Shh) is a secreted protein that is involved in the organization and patterning of several tissues in vertebrates. We show that the zebrafish sonic-you (syu) gene, a member of a group of five genes required for somite patterning, is encoding Shh. Embryos mutant for a deletion of syu display defects in patterning of the somites, the lateral floor plate cells, the pectoral fins, the axons of motorneurons and the retinal ganglion cells. In contrast to mouse embryos lacking Shh activity, syu mutant embryos do form medial floor plate cells and motorneurons. Since ectopic overexpression of shh in zebrafish embryos does not induce ectopic medial floor plate cells, we conclude that shh is neither required nor sufficient to induce this cell type in the zebrafish.
The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired. (1993)

The endocytosis of gp185erbB-2 was studied using chimeric receptors in which the intracellular domain of erbB-2, or subdomins thereof, was substituted for the corresponding regions of the epidermal growth factor (EGF) receptor. Chimeric and wild-type EGF or erbB-2 receptors were expressed in mouse NIH3T3 or NR6 fibroblasts and in a human mammary adenocarcinoma cell line, MDAMB-134. The rate of EGF-induced internalization for the chimera consisting of the extracellular EGF receptor domain and intracellular erbB-2 domain was reduced three- to fourfold compared with the wild-type EGF receptor. The low rate of internalization of the chimeric receptor resulted in impaired down-regulation and degradation of the receptor. Substitution of the carboxyl terminus of erbB-2 for the corresponding region of the EGF receptor caused a similar decrease of receptor endocytosis, whereas substitution of the erbB-2 tyrosine kinase domain did not affect internalization and down-regulation. Since the tyrosine kinase of the internalization-defective chimeric receptors could be activated by EGF, kinase activity and autophosphorylation of erbB-2 do not appear to be sufficient for a maximum rapid internalization of the chimeric receptors. These results suggest that the carboxyl terminus of erbB-2 either does not possess all the signals required for the rapid internalization or contains an inhibitory signal for rapid internalization.
INCREASING UTILIZATION OF BONE MARROW TRANSPLANTATION (1989)

The International Bone Marrow Transplant REgistry conducts periodic surveys to determine activity in the field of allogeneic and syngeneic bone marrow transplantation. Data were reported to the IBMTR by 258 institutions in 41 countries regarding their patients who received bone marrow transplants during the period 1985-1987. To the best of our knowledge, the data represent essentially all bone marrow transplants (exclusive of autologous transplants) performed in the past 3 years. A total of 10,887 patients received bone marrow transplants; 73% were for leukemia, 11% for other malignant diseases, 9% for severe aplastic anemia and related disorders, 3% for immune deficiency diseases, 2% for thalassemia major, and 2% for genetic, metabolic, and several other rare diseases. 161 (62%) of the 258 institutions performed fewer than one transplant per month. More than 50% of the patients were transplanted in 37 institutions. 46% of the world's bone marrow transplants were performed in North America, 42% in Western Europe, 5% in Asia, 3% in Australia and New Zealand, 2% in the Mideast and Africa, 1% in South and Central America, and 1% in Eastern Europe and the USSR. The data reflect continued growth in utilization of allogeneic and syngeneic bone marrow transplantation and quantify the annual increases in the number of patients receiving transplants.
A Multi-Layer Mandatory Access Control Mechanism for Mobile Devices Based on Virtualization (2008)

In this paper we present a multi-layer mandatory access control mechanism (ACM) for mobile devices based on system virtualization technology. We discuss a detailed threat model to mobile devices in the real world to develop an ACM fitted to mobile devices. Then, we propose a novel multi-layer access control mechanism for mobile devices, which provides strong protection against the identified mobile threats as well as performance efficiency. Our Virtual Machine Monitor (VMM) and secure domain have independent access control modules to effectively control mobile device's resources. Access control module at VMM controls access requests from a domain to physical/virtual resources in order to confine sharing resources among domains for confidentiality. It also protects a mobile device against DoS attacks draining limited system resources such as battery and memory to guarantee availability. In addition, access control at secure domain enforces fine-grained control of resources (e.g., file system access control) in upper layer without degrading performance of a mobile device due to additional hypercall invocations. Furthermore, there is no bypass of our access control since our ACM is placed inside VMM which is simple and small enough to verify its safety and we eliminated the chance of VMM corruption by checking integrity of VMM including ACM during bootstrap time.
Maximizing the Natriuretic Peptide System in Experimental Heart Failure (2002)

This study reports that acute VPI potentiates the cardiorenal actions of SQ BNP in experimental CHF. This study advances the concept that protein therapy with BNP together with vasopeptide inhibition represents a novel therapeutic strategy in CHF to maximize the beneficial properties of the natriuretic peptide system.
Neuronal cell adhesion molecules and cytotactin are colocalized at the node of Ranvier. (1986)

Immunocytochemical methods were used to show that Ng-CAM (the neuron-glia cell adhesion molecule), N-CAM (the neural cell adhesion molecule), and the extracellular matrix protein cytotactin are highly concentrated at nodes of Ranvier of the adult chicken and mouse. In contrast, unmyelinated axonal fibers were uniformly stained by specific antibodies to both CAMs but not by antibodies to cytotactin. Ultrastructural immunogold techniques indicated that both N-CAM and Ng-CAM were enriched in the nodal axoplasm and axolemma of myelinated fibers as well as within the nodal regions of the myelinating Schwann cell. At embryonic day 14, before myelination had occurred, small-caliber fibers of chick embryos showed periodic coincident accumulations of the two CAMs but not of cytotactin, with faint labeling in the axonal regions between accumulations. Cytotactin was found on Schwann cells and in connective tissue. By embryonic day 18, nodal accumulations of CAMs were first observed in a few medium- and large-caliber fibers. Immunoblot analyses indicated that embryonic to adult conversion of N-CAM and a progressive decrease in the amount of Ng-CAM and N-CAM occurred while nodes were forming. Sciatic nerves of mouse mutants with defects in cell interactions showed abnormalities in the distribution patterns and amount of Ng-CAM, N-CAM, and cytotactin that were consistent with the known morphological nodal disorders. In trembler (+/Tr), intense staining for both CAMs appeared all along the fibers and the amounts of N-CAM in the sciatic nerve were found to be increased. In mice with motor endplate disease (med/med), Ng-CAM and N-CAM, but not cytotactin, were localized in the widened nodes. Both trembler and med/med Schwann cells stained intensely for cytotactin, in contrast to normal Schwann cells which stained only slightly. All of these findings are consistent with the hypothesis that surface modulation of neuronal CAMs mediated by signals shared between neurons and glia may be necessary for establishing and maintaining the nodes of Ranvier.
The electroluminescent lamp: A new light source (1954)

Important characteristics of electroluminescent lamps are presented together with the most plausible mechanisms of electroluminescence and the three general types of applications.
Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts (2011)

Selective glycolytic inhibition (GI) promotes electromechanical alternans and triggered beats in isolated cardiac myocytes. We sought to determine whether GI promotes triggered activity by early afterdepolarization (EAD) or delayed afterdepolarizations in intact hearts isolated from adult and aged rats. Dual voltage and intracellular calcium ion (Ca(i)(2+)) fluorescent optical maps and single cell glass microelectrode recordings were made from the left ventricular (LV) epicardium of isolated Langendorff-perfused adult (∼4 mo) and aged (∼24 mo) rat hearts. GI was induced by replacing glucose with 10 mM pyruvate in oxygenated Tyrode's. Within 20 min, GI slowed Ca(i)(2+) transient decline rate and shortened action potential duration in both groups. These changes were associated with ventricular fibrillation (VF) in the aged hearts (64 out of 66) but not in adult hearts (0 out of 18; P < 0.001). VF was preceded by a transient period of focal ventricular tachycardia caused by EAD-mediated triggered activity leading to VF within seconds. The VF was suppressed by the ATP-sensitive K (K(ATP)) channel blocker glibenclamide (1 μM) but not (0 out of 7) by mitochondrial K(ATP) block. The Ca-calmodulin-dependent protein kinase II (CaMKII) blocker KN-93 (1 μM) prevented GI-mediated VF (P < 0.05). Block of Na-Ca exchanger (NCX) by SEA0400 (2 μM) prevented GI-mediated VF (3 out of 6), provided significant bradycardia did not occur. Aged hearts had significantly greater LV fibrosis and reduced connexin 43 than adult hearts (P < 0.05). We conclude that in aged fibrotic unlike in adult rat hearts, GI promotes EADs, triggered activity, and VF by activation of K(ATP) channels CaMKII and NCX.
Authorization management for digital libraries (2001)

article Share on Authorization management for digital libraries Authors: H. M. Gladney IBM Almaden Research Center, San Jose, CA IBM Almaden Research Center, San Jose, CAView Profile , Arthur Cantu IBM Almaden Research Center, San Jose, CA IBM Almaden Research Center, San Jose, CAView Profile Authors Info & Claims Communications of the ACMVolume 44Issue 5May 2001pp 63–65https://doi.org/10.1145/374308.374343Published:01 May 2001Publication History 5citation1,075DownloadsMetricsTotal Citations5Total Downloads1,075Last 12 Months3Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
The Autoimmune Basis of Dilated Cardiomyopathy (1995)

Dilated cardiomyopathy is a form of heart disease characterized by ventricular dilatation and reduced systolic function. In most patients, dilated cardiomyopathy is a sporadic disease. However, 20% of dilated cardiomyopathy patients may have a familial form of the disease. The aetiologies of both the sporadic and familial forms of dilated cardiomyopathy are unknown in most cases. Dilated cardiomyopathy has a spectrum of clinical and subclinical presentations. During the last 10 years, there have been many investigations concerning the possible aetiologic role of immune factors in dilated cardiomyopathy. It is plausible that an antecedent viral infection initiates an immunological cascade which in turn leads to production of autoimmune antibodies resulting in dilated cardiomyopathy. However, in most dilated cardiomyopathy patients, an antecedent viral infection cannot be identified. Similarly, the trail of immunological research has diverged as different groups have identified distinct autoantibodies or other immune factors in heterogeneous subsets of dilated cardiomyopathy and control patients. In this manuscript, we review the studies which have contributed supportive and confounding evidence to the theoretical autoimmune basis of dilated cardiomyopathy.
DATATRAK automatic vehicle location and position reporting system (2003)

This system is designed specifically for land use, although equally efficient on boats and aircraft, particularly helicopters. Hyperbolic radio location is used with low-frequency transmitters spaced at 150 km intervals. Time division multiplexing permits up to 32 transmitters on one pair of frequencies. A one-way data system synchronized to navigation transmission, permitting the use of time slot multiplexing over 1500 vehicles reporting every minute, can be accommodated on one frequency. Base stations collect the data from vehicles and pass it to a data network for transmission to control rooms. Displays, digital maps, plotters, and VDU displays give a comprehensive display facility to users. The compact vehicle equipment consists of the LF navigation receivers, a powerful microprocessor board, the UHF transmitter and a stabilized power supply. The unit measures 67 mm*207 mm*265 mm and has a power consumption of 40 W. An active antenna is diplexed to receive LF and transmit UHF. Applications to high value load carriers, general freight operators, emergency services and public transport are considered.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>