gebhart/patrepeval huggingface dataset:
Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma (2001)

EGFR reactivity of 2+ and 3+ may provide a framework for a scoring system. It may be important to evaluate EGFR reactivity in the deepest region of tumor invasion because this region appears to contain the largest percentage of 3+ reactive cells and appears to have the strongest correlation with survival length and EGFR reactivity in lymph node and liver metastases.
Impact of swept source optical coherence tomography on ophthalmology (2015)

Swept source optical coherence tomography (SS-OCT) was introduced in clinical practice in 2012. Because of its deeper penetration and faster acquisition time, SS-OCT has the ability to visualize choroid, vitreous, and retinal structures behind dense preretinal hemorrhages. Swept source optical coherence tomography has positively influenced and hugely contributed to the research of the vitreous body. It is the first ophthalmic diagnostic technology to demonstrate the entire structure of the posterior precortical vitreous pocket (PPVP) <i>in vivo</i>. The roles of the PPVP in physiological posterior vitreous detachment and vitreoretinal interface disorders have now been elucidated. The presence of a connecting channel between the PPVP and Cloquet's canal suggests that the aqueous humor drains into the premacular space. Deeper penetration of SS-OCT has made it possible to view the choroid. It also has an important role in central serous chorioretinopathy and uveitis. We have also been able to treat Harada disease by monitoring the choroidal thickness by SS-OCT.
An airborne 95 GHz dual-polarized radar for cloud studies (1994)

A 95 GHz dual-polarization radar system was developed and flown on the University of Wyoming King Air research aircraft, from which it measured reflectivity, depolarization, and Doppler-derived velocity mean and standard deviation of a variety of clouds. This paper describes the radar and a data acquisition system that uses commercially available digitizers, signal processors, and signal generators. The authors also describe the tradeoffs between spatial resolution and ability to estimate reflectivity and velocity. This paper presents the first known airborne measurements of clouds made at 95 GHz; these are thought to be the most highly resolved millimeter-wave cloud images made to date. Depolarization, measured in terms of the linear depolarization ratio (LDR), was especially high in the melting band and in regions containing pristine ice crystals. These measurements demonstrate the advantages that high-spatial-resolution airborne millimeter-wave radars offer for the study of cloud microphysical properties.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Institutes of regional development and competitiveness in the conditions of modernization (2011)

This paper discusses the problem of identifying institutions that influence the development of the regions. The role of institutions in the concept of regional competitiveness is reviewed. Institutional systematization of institutions for regional development is implemented. Quantitative analysis results of the influence on indicators of regional development by a series of institutions are published.
In vivo quantification of regional myocardial blood flow: Validity of the fast‐exchange approximation for intravascular <i>T</i><sub>1</sub> contrast agent and long inversion time (2006)

In the present study we investigated the effects of water exchange between intra- and extravascular compartments on absolute quantification of regional myocardial blood flow (rMBF) using a saturation-recovery sequence with a rather long inversion time (TI, 176 ms) and a T1-shortening intravascular contrast agent (CMD-A2-Gd-DOTA). Data were acquired in normal and ischemically injured pigs, with radiolabeled microsphere flow measurements used as the gold standard. Five water exchange rates (fast, 6 Hz, 3 Hz, 1 Hz, and no exchange) were tested. The results demonstrate that the fast-exchange approximation may be appropriate for rMBF quantification using the described experimental setting. Relaxation rate change (DeltaR1) analysis improved the accuracy of the analysis of rMBF compared to the MR signal. In conclusion, the current protocol could provide sufficient accuracy for estimating rMBF assuming fast exchange and a linear relationship between signal and tissue concentration when quantification of precontrast T1 is not an option.
Shot profile dip moveout using log‐stretch transform (1986)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1986Shot profile dip moveout using log‐stretch transformAuthors: Biondo BiondiShuki RonenBiondo BiondiStanford University and Shuki RonenSaxpy Computer Co.https://doi.org/10.1190/1.1893056 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InReddit Permalink: https://doi.org/10.1190/1.1893056FiguresReferencesRelatedDetailsCited bySeismic data reconstruction by inversion to common offsetNizar Chemingui and Biondo Biondi17 September 2002 | GEOPHYSICS, Vol. 67, No. 5DIP-moveout by Fourier transformComputer Physics Communications, Vol. 52, No. 3 SEG Technical Program Expanded Abstracts 1986 ISSN (print):1052-3812 ISSN (online):1949-4645 Copyright: 1986 Pages: 715 publication data© 1986 Copyright © 1986 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 07 Mar 2005 CITATION INFORMATION Biondo Biondi and Shuki Ronen, (1986), "Shot profile dip moveout using log‐stretch transform," SEG Technical Program Expanded Abstracts : 431-434. https://doi.org/10.1190/1.1893056 Plain-Language Summary PDF DownloadLoading ...
Ceramic Structures by Selective Laser Sintering of Microencapsulated, Finely Divided Ceramic Materials (2018)

The feasibility of producing ceramic green parts by Selective Laser Sintering\nfrom microencapsulated, finely divide ceramic powders has been reported in\nan earlier paper. Post-processing of a silica/zirconium orthosilicate system\nand an alumina system, both utilizing a polymer binder in the form of a\ncoating, are discussed in this paper. Ceramic green parts require postprocessing\nto remove the intermediate polymer binder and to impart strength\nproperties to the ceramic bodies. In this paper, the use of ceramic cements\nand high temperature firing to realize strengths will be discussed. The effects\nof cement concentration and controlled drying rates on the strengths and\ndimensional accuracy of the ceramic bodies are also discussed.
Advances in liquid-toner technology and their applications (1990)

The purpose of this paper is to describe recent advances in liquid toner technology and their applications, both present and potential. As a preface, it is important to keep in mind that liquid toners represent only a segment of an overall imaging system that also incorporates hardware, media and quite possibly, pertinent software. Recent advances in toner design has occurred as a direct outcome of simultaneous advances in the design of the overall imaging system.
Synthesis of resorcin[4]arene cavitands by ring-closing metathesis (2007)

The synthesis and X-ray crystal structures of the first resorcin[4]arene cavitands by ring-closing metathesis reaction are described.
Undoped InP/InGaAs heterostructure insulated-gate FET's grown by OMVPE with PECVD-deposited SiO/sub 2/ as gate insulator (1988)

The fabrication and performance of InP/InGaAs insulated-gate FETs which use a heterojunction to isolate the channel electrons from the semiconductor-insulator interface are discussed. Plasma-enhanced chemical vapor deposition (PECVD) was used to deposit SiO/sub 2/ on InP to form the gate insulator. Since the device structure is undoped, channel electrons are accumulated by the gate-induced field across the insulator. Extrinsic transconductances of 130 mS/mm (300 K) and 210 mS/mm (77 K) were achieved for 1.5- mu m gate-length devices. Gate-drain breakdown voltages in excess of 20 V were also measured.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
β <sub>2</sub> -Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein (1998)

G protein-coupled receptor activation leads to the membrane recruitment and activation of G protein-coupled receptor kinases, which phosphorylate receptors and lead to their inactivation. We have identified a novel G protein-coupled receptor kinase-interacting protein, GIT1, that is a GTPase-activating protein (GAP) for the ADP ribosylation factor (ARF) family of small GTP-binding proteins. Overexpression of GIT1 leads to reduced beta2-adrenergic receptor signaling and increased receptor phosphorylation, which result from reduced receptor internalization and resensitization. These cellular effects of GIT1 require its intact ARF GAP activity and do not reflect regulation of GRK kinase activity. These results suggest an essential role for ARF proteins in regulating beta2-adrenergic receptor endocytosis. Moreover, they provide a mechanism for integration of receptor activation and endocytosis through regulation of ARF protein activation by GRK-mediated recruitment of the GIT1 ARF GAP to the plasma membrane.
Enzymic Hydrolysis of Colanic Acid (1971)

The isolation of of oligosaccharides produced by the action of phage-inducee enzymes on the bacterial exopolysaccharide colanic acid is reported. The products from colanic acid produced by different strains of Escherichia coli and Salmonella typhimurium were hexasaccharides which differed in their acyl substituents. All contained fucose, glucose, galactose and glucuronic acid in the molar ratio 2:1:2:1. They appeared to have the same carbohydrate structure as that postulated for the repeating unit of colanic acid. All the hexasaccharides contained acetate. Pyruvate was also found in most preparations. The phage-induced enzymes only converted 30–35% of the polymer to oligosaccharides. They also hydrolysed de-acetylated polysaccharide but were inactive against carboxyl-reduced material and against a number of other bacterial exopolysaccharides.
A real-time digital speech processing system for an auditory prosthesis (2003)

A fully programmable digital speech-processing system for multichannel electrical stimulation of the cochlea is described. The system consists of laboratory testing station as well as a battery-powered portable processing unit, both of which use the Texas Instrument 320C25 signal processing chip. The laboratory station uses a Microvax II equipped with the TI signal-processing chip on a custom-built coprocessing board to combine the capability of real-time speech analysis and coding with the ability for real-time adaptation of processing algorithms to individual cochlear implant patients. The portable speech processor is a low-power (0.8-W) unit designed to run algorithms that were tested and customized with the laboratory station. An example application of the system is discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Vascular Tissue-Specific Gene Expression of Xylem Sap Glycine-Rich Proteins in Root and Their Localization in the Walls of Metaxylem Vessels in Cucumber (2000)

Root-specific cDNAs of glycine-rich protein (cucumber root glycine rich protein-1 and -2; CRGRP-1 and CRGRP-2) were cloned previously by use of an antiserum raised against whole xylem sap of Cucumis sativus. The accumulation of the corresponding mRNA at high levels was detected in the root-hair zone of cucumber tap root [Sakuta et al. (1998) Plant Cell Physiol. 39: 1330]. The RNA gel blot analysis with the CRGRP-1- and -2-specific probes revealed that the CRGRP genes expressed only in root but not at all in aboveground organs. When the localization of these mRNAs were examined by in situ hybridization, CRGRP mRNAs were found only in the parenchyma cells in the central cylinder of young lateral roots and it was most abundant in the cells that surrounded xylem vessels in the root-hair zone of the tap root. In immunoblotting of xylem sap collected from cucumber stem with an antiserum raised against CRGRP-1 that had been produced in an E. coli expression system, the antibodies, which did not cross-react with GRP1.8 of kidney bean, reacted with two proteins, whose mobilities corresponded to those of proteins deduced from the CRGRP-1 and -2 cDNAs. Immunohistochemical staining revealed that the CRGRPs accumulated specifically in the lignified walls of metaxylem vessels in the root, stem and leaf and in the lignified cell walls of perivascular fibers in cucumber stems. Immunostaining was also detected in the walls of metaxylem vessels and in the cell walls of adjacent sclerenchyma in the hypocotyl of kidney bean. These data clearly indicate that the novel glycine-rich proteins were produced in the vascular tissue of the root, transported systemically over a long distance via the xylem sap and immobilized in the walls of metaxylem vessels and sclerechyma cells in aboveground organs.
A Portable Microprocessor-Based Biofeedback Training Device (1980)

We have designed and constructed a portable microprocessor-based feedback instrument for speech therapy with Parkinson's disease patients. The instrument is very flexible due to its programmability and ease of interface to analog modules, Our first implemented application provides biofeedback about speech-volume levels. This device monitors speech-volume levels of a patient, provides performance feedback for the patient, and logs the performance data in its semiconductor memory. In tests on a patient with Parkinson's disease, the instrument functioned well when optimized through programming.
Cyclosporine Treatment Promotes Survival of Human Fetal Neural Retina Transplanted to the Subretinal Space of the Light-Damaged Fischer 344 Rat (1996)

We have reported that xenografts of human fetal neural retina survive in the subretinal space of cyclosporine-immunosuppressed rats. In view of the current controversy regarding the role of cyclosporine, we wished to determine if cyclosporine immunosuppression was an absolute requirement for retinal xenograft survival. Neural retinas from human fetal eyes obtained within 1 h of termination of pregnancy were stored in Optisol medium (Chiron Vision, Irvine, CA) at 4 degrees C for 2 and 7 days. Retinas were then transplanted to the subretinal space of either cyclosporine-treated (10 mg/kg/day) light-damaged Fischer 344 rat eyes (17 animals, 28 eyes) or to the subretinal space of light-damaged Fischer 344 rat eyes (9 animals, 15 eyes) receiving no cyclosporine treatment. Grafted eyes were observed clinically at 10, 20, and 30 days posttransplantation. At 30 days, the animals were sacrificed and the grafts observed histologically. Human fetal retina xenografted to the subretinal space of immunosuppressed rats survived (9/17 animals, 12/28 eyes), showed good integration with the host retina and initial photoreceptor differentiation. Tissue xenografted to the subretinal space of non-cyclosporine-treated rats was not observed to survive (0/9 animals, 0/15 eyes). A low level cellular reaction was seen around three of the injection sites within the nonimmunosuppressed rats. We conclude that immunosuppression is necessary for the survival of human fetal neural retina xenografted to the subretinal space.
Chronic opioid therapy as alternative treatment for post-herpetic neuralgia (1994)

Neurosurgical procedures such as the dorsal root entry zone operation, ganglionectomy, and spinal-cord stimulation have been offered to patients with intractable post-herpetic neuralgia (PHN). Poor efficacy or high morbidity have limited the overall usefulness of these procedures. We recently conducted a preliminary open-label study with long-acting oral opioids. The mean pretreatment pain score, on a scale of 0 to 10 (0 = no pain) was 9.0 +/- 0.3 (mean +/- SEM, N = 20). At two months of treatment the average pain score was 4.0 +/- 0.4 (p < 0.001, paired t test), and at six months the average pain score was 3.8 +/- 0.2 (p < 0.001, N = 16). These observations warrant a controlled opioid trial for patients affected by PHN.
Adaptive control mechanism for cable modem MAC protocols (2002)

Cable plants were initially designed for one-way broadcast of analog television signals (from the head-end to the neighborhood). They are now being upgraded to provide an upstream path (from the home to the head-end). New challenges arise in using the upstream channel since the available bandwidth is low and the noise levels are high. Different variations of the reservation Aloha protocol have been proposed as the MAC protocol to efficiently share the scarce upstream capacity. The efficiency of the reservation protocol highly depends on the capacity assigned to the reservation channel. In this paper we present a control mechanism that dynamically adjusts the operating parameters to the current load on the system. The control mechanism does not require any framing structure and is built around a "sea of mini-slots". The performance under both static and highly dynamic loads is close to optimum. The station implementation remains particularly simple and the downstream control structure is also simple. Results are given here for fixed length data units (ATM cells) but the algorithm extends very simply to variable length MAC frames.
Improved Permeability Estimates in Carbonate Reservoirs Using Electrofacies Characterization: A Case Study of Mumbai High South (2011)

Electrofacies Characterization is a simple and cost-effective approach to obtaining permeability estimates in heterogeneous carbonate reservoirs using commonly available well logs. Permeability is one of the most important characteristics of hydrocarbon bearing formations in a reservoir. Formation permeability is often measured directly from core samples in the laboratory or evaluated from the well test data. The first method is very expensive. Moreover, the well test data or core data are not available in every wells in a field, however majority of wells are logged. Permeability determination is an active research area in petroleum industry as there is no direct formula for calculation of permeability from logs. In this paper, we proposed a two-step approach. First, we classify the well-log data into electrofacies types. This classification does not require any artificial subdivision of the data population but follows naturally based on the unique characteristics of well-log measurements, reflecting minerals and lithofacies within the logged interval. A combination of principal component analysis (PCA), model-based cluster analysis (MCA), and discriminant analysis is used to identify and characterize electrofacies types. Second, we apply nonparametric regression techniques, the Alternating Conditional Expectation (ACE) algorithm, to predict permeability using well logs within each electrofacies. Such techniques are completely data-driven and do not require a priori assumptions regarding functional forms for correlating permeability and well logs. We applied the proposed technique to a highly heterogeneous carbonate reservoir in the Mumbai High South for generation of permeability transform. Such developed permeability transform by the aforementioned technique can solve problems for estimating continuous permeability profiles more accurately in uncored wells. This approach appears to result in better permeability predictions, leading to an enhanced reservoir characterization based on flow, permeability (rather than storage), or porosity in Mumbai High South. This can have potential benefits both in daily operations and in reservoir simulation efforts. This application also envisages the power and versatility of electrofacies characterization in improving reservoir descriptions in complex carbonate reservoirs.
Specificity of bile salt sulfatase activity from Clostridium sp. strains S1 (1982)

Clostridium sp. strain S1, an unnamed bile acid-desulfating strain from rat intestinal microflora (S.M. Huijghebaert, J. A. Mertens, and H. J. Eyssen, Appl. Environ. Microbiol. 43:185-192, 1982), was examined for its ability to desulfate different bile acid sulfates and steroid sulfates in growing cultures. Clostridium sp. strain S1 desulfated the 3 alpha-monosulfates of chenodeoxycholic, deoxycholic, and cholic acid, but not their 7 alpha- or 12 alpha-monosulfates. Among the 3-sulfates of the 5 alpha- and 5 beta-bile acids, only bile acid-3-sulfates with an equatorial sulfate group were desulfated. Hence, Clostridium sp. strain S1 desulfated the 3-sulfates of bile acids with a 3 alpha, 5 beta-, a 3 beta, 5 alpha- or a 3 beta, delta 5-structure. In contrast, the bile acid-3-sulfates with a 3 beta, 5 beta- or a 3 alpha, 5 alpha-structure were not desulfated. In addition, Clostridium sp. strain S1 did not hydrolyze the equatorial 3-sulfate esters of C19 and C21 steroids and cholesterol or the phenolic 3-sulfate esters of estrone and estradiol. 23-Nordeoxycholic acid with a C-23 carboxyl group was also not desulfated, in contrast to the 5 beta-bile acid 3 alpha-sulfates with a C-24 or C-26 carboxyl group. Therefore, the specificity of the sulfatase of Clostridium sp. strain S1 is related to the location of the sulfate group on the bile acid molecule, the equatorial orientation of the sulfate group, and the structure of the C-17 side chain, its carboxyl group, and chain length.
Smart antenna arrays with oscillating beam patterns: characterization of transmit diversity in semi-elliptic coverage (2002)

By applying carefully selected time-varying delays to the array elements of a smart antenna located at the base station (BS), small oscillations are generated in the beam pattern. These oscillations create a time-varying channel demonstrating intra-symbol time variation and characterized by coherence time T/sub C/. At a single-antenna mobile station (MS), the time-varying channel (with coherence time T/sub C/) creates a time diversity which is exploited to enhance the mobile's performance (by introducing oversampling to the mobile receiver). We present a channel model which characterizes the time-varying channel that results from beam pattern oscillation. We then use our channel model to evaluate the coherence time, T/sub C/, at the mobile station (MS). The channel model presented corresponds to the so-called geometric-based stochastic channel model (GSCM), with a semi-elliptic coverage area. This geometric approach allows us to stochastically model the parameters of the time-varying channel impulse response. Simulations based on the GSCM show that 7-fold time diversity can be exploited at the MS (when beam pattern movement is small), which significantly improves the MS receiver probability-of-error performance.