gebhart/patrepeval huggingface dataset:
Digital performance of high-speed MSM-HEMT monolithically integrated photoreceivers (2002)

In this work, we report the first multigigabit digital performance of a monolithic MSM-HEMT photoreceiver lattice matched to an InP substrate, with measured sensitivities at 5 Gb/s, 8 Gb/s, and 10 Gb/s of -16.9 dBm, -13.1 dBm, and -10.7 dBm, respectively for 1.55 /spl mu/m light. The integration of MSM-PD and HEMT is done via a vertical integration scheme in which the HEMT and MSM layers are grown sequentially on a planar substrate in a single uninterrupted growth. The integration process features 0.2 /spl mu/m gate length HEMTs, 0.5 /spl mu/m MSM electrodes, Cr thin-film resistors, and SiN/sub x/ metal-insulator-metal capacitors, passivation, and photodetector antireflection coatings. The receiver circuit uses a low-noise three-stage transimpedance amplifier topology, with broadband output matching to 50 /spl Omega/. Two different amplifier designs were fabricated, resulting in systems with transimpedances ranging from 865 to 580 /spl Omega/ and bandwidths from 7.2 to 12.4 GHz. In all cases, the frequency response is flat over the receiver bandwidth, with no evidence of peaking or ringing. Receiver output noise power spectral density measurements have also been performed, and the input-referred noise current determined for each receiver. The low-noise amplifier design results in input noise current densities of approximately 6.5 pA/Hz/sup 1/2/ for a transimpedance of 865 /spl Omega/ and bandwidth of 7.2 GHz, and 8 pA/Hz/sup 1/2/ for a transimpedance of 580 /spl Omega/ and bandwidth of 12.4 GHz.
Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: A systematic review of the experience in industrialized countries (2011)

The pentavalent rotavirus (RV) vaccine RotaTeq™ has been available in industrialized countries since 2006. Several studies have been conducted to evaluate the benefit of RV vaccination under routine conditions of use. A systematic review of all publicly available data from RotaTeq™ vaccine-effectiveness and vaccination-impact studies in the USA, Europe and Australia between 2006 and February 2010 was undertaken. Depending on the population studied, effectiveness of up to 100% (95% confidence interval 85-100%) associated with decreased hospitalizations for RV gastroenteritis (RVGE) was seen. Vaccination-impact studies demonstrated that the burden of RVGE has been reduced significantly since the introduction of RV vaccination. Evidence included reductions in healthcare utilization due to RVGE (hospitalizations and emergency-department visits reduced by up to 90%), reductions in the magnitude and duration of the RV season as assessed by laboratory testing for RV, and the possible induction of herd immunity.
The platelet release reaction: just when you thought platelet secretion was simple (2008)

A complex set of protein-protein interactions control the membrane fusion events required for the platelet release reaction. SNARE proteins are the core elements but the proteins that control SNARE interactions represent key points at which platelet signaling cascades could affect secretion and thrombosis.
Frequency Selective Surface for reducing mutual coupling in antenna arrays (2011)

In this paper the effect of using one type of FSS called Split Ring Resonator (SRR) on reducing the mutual coupling between the antenna array elements has been investigated. The popular property of these types of resonators is that they have negative permeability near their magnetic resonant frequency which causes SRRs to show stop band behavior in their transmission (S 21 ) curves [1–3]. In this study the effect of SRRs on the performance of two types of antenna arrays; Microstrip patch antenna array and monopole antenna array have been investigated. Placing the SRR arrays in between the antenna array's elements has caused a considerable reduction of 10 dB in the amount of mutual coupling between the elements of the microstrip patch antenna array and a considerable reduction of 20 db in the amount of mutual coupling between the monopole antenna array elements.
Robust Human Tracking Algorithm Applied for Occlusion Handling (2010)

The robust tracking algorithm is presented that can automatically track the human including partial or total occlusion in the paper. Firstly, as a result of the use of Camshift, the effectiveness of particle is improved, and the tracking window can change scale with the target adaptively; Secondly, the multiple cues integration technique is brought into the framework of Camshift guided particle filter method to improve tracking robustness; Finally, an occlusion strategy is proposed to deal with the full occlusion for a long time. The occlusion strategy based on the direct color-motion integration mechanism is adopted, which can realize steady target tracking, and reinitialize tracking automatically when the lost object reappears. The experiments show that the algorithm is effective to moving target tracking with occlusion. Its effectiveness is proved through quantitative analysis.
The Levels of Sera Malondialdehyde, Erythrocyte Membrane Na+-K+/Mg++ and Ca++/Mg++ Adenosine 5' Triphosphatase in Patients with Sickle Cell Anemia. (2000)

The various membrane abnormalities of sickle erythrocytes may result from excessive accumulation of oxidant damage. We measured the sera levels of malondialdehyde, products of lipid peroxidation, Na+-K+/Mg++ Adenosine 5' triphosphatase (ATPase) and Ca++/Mg++ Adenosine 5' triphosphatase, erythrocyte membrane enzymes, in patients with sickle cell anemia and compared their levels with that of normal controls. MDA, Na+-K+/Mg++ and Ca++/Mg++ ATPase levels of control groups were 0.90 ± 0.04 nmol/mL, 168 ± 12.9 and 140.6 ± 8.2 nmol Pi/mg prot/hour, respectively. MDA, Na+-K+/Mg++ and Ca++/Mg++ATPase levels of patients were 2.02 ± 0.01 nmol/mL, 127.0 ± 8.4 and 110.0 ± 9.6 nmol Pi/mg prot/hour, respectively. Our experimental results showed that there was a significant increase in MDA levels of patients with sickle cell anemia as compared with that of the controls. However, erythrocyte membrane Na+-K+/Mg++ and Ca++/Mg++ ATPase levels of patients with sickle cell anemia were significantly lower than the, Na+-K+/Mg++ and Ca++/Mg++ ATPase levels of normal controls.
Engineering multistage diode logic circuits (1955)

THIS article presents the method used for engineering the multistage diode logical function circuitry for a special-purpose computer employing exclusively semiconductor devices. Although the techniques used have been largely influenced by the devices available or being developed for the rest of the system, it is felt that these devices are typical of the general type of transistor device which may be expected in the near future. The methods to be described are partly graphical: no assumption of constant forward diode resistance is made. In this way, they differ from analysis methods based on Thévenin's theorem.
Data regularization for 3D SRME: A comparison of methods (2007)

This paper discusses and compares different strategies for data regularization prior to the application of 3‐D SRME. It is shown that synthetic analysis can be utilized to determine whether azimuth corrections are needed during data regularization. It is shown that only in certain instances this is needed, depending on the azimuth between the dipping reflectors and the acquisition direction. Also, the reflector dips, offset ranges and the reflectors depths are important. For geometries where azimuth corrections are needed, a comparison is made between two well‐known solutions: Forward DMO followed by inverse DMO (DMO‐DMO−1) regularization, and Fourier regularization with azimuth correction. It is shown that the latter shows better performance in terms of amplitude fidelity, as well as dealing with practical issues such as irregular sampling due to feathering of the streamers. Application of the Fourier regularization method to a field data set shows that the method is very capable of predicting complex 3‐D multiples in the presence of multiple diffractions.
When Ends Meet: Circular DNA Stretches Differently in Elongational Flows (2015)

Chain topology has a profound impact on the flow behavior of single macromolecules. For circular polymers, the absence of free ends results in a unique chain architecture compared to linear or branched chains, thereby generating distinct molecular dynamics. Here, we report the direct observation of circular DNA dynamics in transient and steady flows for molecular sizes spanning the range of 25.0–114.8 kilobase pairs (kbp). Our results show that the longest relaxation times of the rings follow a power-law scaling relation with molecular weight that differs from that of linear chains. Also, relative to their linear counterparts, circular DNA molecules show a shifted coil-to-stretch transition and less diverse “molecular individualism” behavior as evidenced by their conformational stretching pathways. These results show the impact of chain topology on dynamics and reveal commonalities in the steady state behavior of circular and linear DNA that extends beyond chain architecture.
Special Topics in Chinese-English Translation (2016)

The present volume is the fruits of the MA projects in the School of Foreign Studies of Yangtze University particularly with respect to English-Chinese translation. It contains five theses which explore such topics as public signs translation, museum texts translation, subtitle translation and poetry translation. The projects have discussed some hot issues in the above fields in the translation between Chinese and English and provided some insights on the issues.
An improved capacitance method of measuring thermal expansion and magnetostriction of amorphous ribbons : application to FeNiCr metallic glasses (1983)

Magnetostriction and thermal expansion can be accurately measured on amorphous ribbons wound in order to get rigid hollow cylinders : the strains are measured along the cylinder axis by means of a capacitance dilatometer. This method, easier and more reliable than the conventional ones, has been tested by studying the magnetoelastic properties of amorphous Fe40-x /2Ni40-x/2CrxMo 2B8S10 alloys. The one-ion character of the magnetostriction has been verified.
Flight characteristics of the AD-1 oblique-wing research aircraft (1985)

The AD-1 is a low-speed oblique-wing research airplane. This report reviews the vehicle's basic flight characteristics, including many aerodynamic, stability, and control effects that are unique to an oblique-wing configuration. These effects include the change in sideforce with angle of attack, moment changes with angle of attack and load factor, initial stall on the trailing wing, and inertial coupling caused by a roll-pitch cross product of inertia. An assessment of the handling qualities includes pilot ratings and comments. Ratings were generally satisfactory through 30 deg of wing sweep but degraded with increased sweep. A piloted simulation study indicated that a basic rate feedback control system could be used to improve the handling qualities at higher wing sweeps.
Recent Advances in Urology/andrology (1991)

MRI in urology recent advances in ultrasound anaerobic infection in urological practice laparoscopic urology management of bladder exstrophy advances in management of renal cell carcinoma orthotopic bladder substitutes chemotherapy for invasive bladder cancer screening for prostate cancer optimal therapy for metastatic prostate cancer the pharmacological management of benign prostatic hyperplasia management of posterior urethral injuries testicular cancer - reducing the toxicity of germ cell tumours penile revascularization.
Using Computer Conferencing and Electronic Mail to Facilitate Group Projects (1995)

This article reports on the use of electronic mail and an electronic conferencing system to conduct group projects in three Educational Psychology courses. Modifying the traditional group project by incorporating electronic communication has a number of advantages. 1) By “meeting” electronically, groups can communicate without space or time restrictions, creating potentially continuous dialogues. 2) Coordinating the groups electronically allows the professor to “sit-in” on these dialogues. The professor can be an unobtrusive observer, instantly available to answer questions, or give advice if the group seems to need it. 3) Monitoring the groups at work also allows the instructor to accurately assess the participation and contributions of each individual in the group, and assign appropriate grades. 4) Finally, the project introduces the students to electronic networking, and gives them a realistic opportunity to practice using it.
Unusual clinicopathological and immunological presentation of chronic bullous dermatosis of childhood (linear IgA dermatosis) (2011)

Linear IgA bullous dermatosis is a rare sulfone-responsive subepidermal blistering disorder of unknown etiology in which smooth linear deposits of IgA are found in the basement membrane zone. Chronic bullous dermatosis of childhood is equivalent to linear IgA disease of adulthood and is characterized by an abrupt onset of large, widespread and tense bullae on a normal or erythematous base. In this case, we describe an unusual presentation of chronic bullous dermatosis in a 14-month-old Saudi girl. Histopathological examination revealed subepidermal cell poor blisters with linear deposition of IgA, IgG, IgM, and C3 along the dermoepidermal junction. The unusual clinical, histopathological and immunofluorescence findings in this patient are discussed, with an account on the differential diagnosis in such cases along with a detailed review of the relevant literature.
Design and prototyping a Fast Hadamard Transformer for WCDMA (2004)

In this paper, the design and implementation of a Fast Hadamard Transformer (FHT) on a field programmable gate array (FPGA) is described. Two possible schemes which use 256 and 16 chip input sequences are compared on a Xilinx Virtex-E XCV1000E FPGA. The results indicate that the 16 chip sequence achieves 90% reduction in hardware resources and more than double the maximum frequency of operation as compared to 256 chip sequences. An application of the proposed FHT design used to perform cell search for Wideband Code Division Multiple Access (WCDMA) system is also presented.
Aripiprazole: pharmacology, efficacy, safety and tolerability (2005)

Aripiprazole is a recently released antipsychotic medication which differs from other atypical antipsychotic agents by its partial agonist activity at postsynaptic D2 receptors. It is administered orally and is distinguished by a long elimination phase half-life relative to other antipsychotic medications. Randomized studies have demonstrated the efficacy of aripiprazole relative to placebo in the treatment of acute relapse of schizophrenia and schizoaffective disorder, maintenance treatment of schizophrenia, and treatment of acute bipolar mania. Aripiprazole is generally well tolerated relative to other antipsychotic medications, although commonly reported side effects include worsening extrapyramidal symptoms and motoric activation similar to akathisia. Further studies and postmarketing data will be helpful in providing additional information about the comparative safety, efficacy and tolerability of aripiprazole.
Cost-effectiveness of hydroxyurea in sickle cell anemia (2000)

The Multicenter Study of Hydroxyurea in Sickle Cell Anemia (MSH) demonstrated the efficacy of hydroxyurea in reducing the rate of painful crises compared to placebo. We used resource utilization data collected in the MSH to determine the cost-effectiveness of hydroxyurea. The MSH was a randomized, placebo-controlled double-blind clinical trial involving 299 patients at 21 sites. The primary outcome, visit to a medical facility, was one of the criteria to define occurrence of painful crisis. Cost estimates were applied to all outpatient and emergency department visits and inpatient hospital stays that were classified as a crisis. Other resources for which cost estimates were applied included hospitalization for chest syndrome, analgesics received, hydroxyurea dosing, laboratory testing, and clinic visits for management of patient care. Annualized differential costs were calculated between hydroxyurea- and placebo-receiving patients. Hospitalization for painful crisis accounted for the majority of costs in both arms of the study, with an annual mean of $12,160 (95% CI: $9,440, $14,880) for hydroxyurea and $17,290 (95% CI: $13,010, $21,570) for placebo. The difference in means was $5,130 (95% CI: $60, $10,200; P = 0.048). Chest syndrome was the next largest cost with a mean difference of $830 (95% CI: $-340, $2,000; P = 0.16). The hydroxyurea arm was also associated with lower costs for emergency department visits, transfusion, and use of opiate analgesics. In total, the annual average cost per patient receiving hydroxyurea was $16,810 (95% CI: $13,350, $20,270) and the annual average costs per patient receiving placebo was $22,020 (95% CI: $17,340, $26,710). The difference in means was $5,210 (95% CI: $-610, $11,030; P = 0.21). The cost of hydroxyurea with the more intensive monitoring required when using this drug appears to be more than offset by decreased costs for medical care of painful crisis and analgesic use. Although the total cost difference was not significant statistically, these results suggest that hydroxyurea therapy is cost-effective compared to placebo in the management of adult patients with sickle cell anemia. If hydroxyurea can prevent development of chronic organ damage, long-term savings may be even greater.
Different Repair Kinetics for Short and Long DNA Double-strand Gaps in <i>Saccharomyces Cerevisiae</i> (1995)

The kinetics of recombinational repair of plasmid DNA double-strand breaks (dsb) and gaps (dsg) of different sizes and ends were studied. For this purpose we used the mutant rad54-3 of the yeast Saccharomyces cerevisiae, which is temperature dependent with respect to genetic recombination and rejoining of dsb/dsg, allowing us to stop these processes by shifting cells to the restrictive temperature. We found that the kinetics of repair of cohesive-ended dsb and small gaps (up to 400 bp) are similar and characterized by two phases separated by a plateau. In contrast, large gap (1.4 kbp) repair proceeds with different kinetics exhibiting only the second phase. We also investigated the repair kinetics of 400 bp gaps introduced into plasmid DNA with and without homology to chromosomal DNA allowing recombinational repair and non-recombinational repair (ligation), respectively. We found that gaps introduced in plasmid sequences homologous to chromosomal DNA are rapidly repaired by recombination. In contrast, recircularization of the gapped plasmid by ligation is as slow and inefficient as ligation of a cohesive-ended dsb. The kinetics of repair of gapped plasmids may be explained by assuming a constitutive level of enzymes responsible for the first phase of recombinational repair, while inducible enzymes, which become available at the end of the plateau, carry out the second phase of repair.
Simulation of electron postacceleration in a two-stage laser wakefield accelerator (2002)

Electron bunches produced in self-modulated laser wakefield experiments usually have a broad energy distribution, with most electrons at low energy (1--3 MeV) and only a small fraction at high energy. We propose and investigate further acceleration of such bunches in a channel-guided resonant laser wakefield accelerator. Two-dimensional simulations with and without the effects of self-consistent beam loading are performed and compared. These results indicate that it is possible to trap about $40%$ of the injected bunch charge and accelerate this fraction to an average energy of about 50 MeV in a plasma channel of a few mm.
Induction of CD4<sup>+</sup>T cell-dependent CD8<sup>+</sup>type 1 responses in humans by a malaria DNA vaccine (2001)

We assessed immunogenicity of a malaria DNA vaccine administered by needle i.m. or needleless jet injection [i.m. or i.m./intradermally (i.d.)] in 14 volunteers. Antigen-specific IFN-gamma responses were detected by enzyme-linked immunospot (ELISPOT) assays in all subjects to multiple 9- to 23-aa peptides containing class I and/or class II restricted epitopes, and were dependent on both CD8(+) and CD4(+) T cells. Overall, frequency of response was significantly greater after i.m. jet injection. CD8(+)-dependent cytotoxic T lymphocytes (CTL) were detected in 8/14 volunteers. Demonstration in humans of elicitation of the class I restricted IFN-gamma responses we believe necessary for protection against the liver stage of malaria parasites brings us closer to an effective malaria vaccine.
Intervening with victims of intimate partner violence (2001)

Intimate partner violence (IPV) is a critically important public health problem. Physicians and other health care providers have a unique opportunity to help IPV victims, not only in treatment but in prevention of this devastating problem. Health-care providers should receive thorough and on-going training and administrative support for identifying, appropriately treating, and referring IPV victims to IPV advocates and other community-based resources with whom the provider has developed a close working relationship. In the clinical setting, health-care providers may intervene early as the victim’s first and only point of contact concerning the violence in their lives. In the larger community, health-care providers can become spokespersons and educators to help change social norms and can get involved in coordinated community responses to ensure cohesive actions by all societal sectors to prevent IPV in their communities.
Ciguatera fish poisoning (1988)

Abstract Ciguatera fish poisoning following consumption of a variety of fishes presents a distinct complex of polymorphous symptoms, including gastrointestinal (abdominal pain, diarrhea, vomiting, nausea), neurological (primarily parasthesia, dysesthesia), and cardiovascular (bradycardia, hypotension, tachycardia). The fishes involved include herbivores (surgeonfish) and carnivores (e.g., snapper, grouper, barracuda, jack, amberjack). Clinical symptoms seem to differ according to whether toxicity is caused by herbivores or carnivores, that is, there seem to be differences between the gastrointestinal and neurological symptoms associated with herbivores, and the gastrointestinal, neurological, and cardiovascular symptoms following consumption of carnivores. The final structure of ciguatoxin (CTX) from a carnivore species (moray eel livers) has been recognized as a lipid polyether closely related to other polyethers from dinoflagellates (okadaic acid, brevetoxin, maitotoxin, scaritoxin), to sponges (okadaic acid and norhalichondrin A), and to the streptomyces (antibiotics, monocarboxylic polyethers). Pharmacological studies suggest that, like the antibiotic polyether ionophores, ciguatoxin (Na +) and its related polyethers likewise affect cell membrane and electrolyte imbalances. Screening of toxin fishes for ciguatoxin and related polyethers may soon be a reality employing monoclonal antibodies in the stick enzyme immunoassay. Research in human diagnostic tests and treatment of afflicted individuals is presently limited for ciguatera poisoning.
A 17 Gb/s, 200-meter Multimode Optical Fiber Link using CMOS Analog ICs and Silicon Carrier Packaging (2006)

We demonstrate a 17 Gb/s optical link using transmitter and receiver CMOS integrated circuits. We achieved error free operation over a 200-meter long OM3 multimode fiber operating at 850 nm
Chidamide combined with cyclophosphamide, doxorubicin, vincristine and prednisone in previously untreated patients with peripheral T-cell lymphoma (2021)

The addition of chidamide to standard CHOP chemotherapy was tolerable with promising preliminary efficacy in previously untreated PTCL patients, which supports further clinical studies with this combination regimen for the frontline treatment of PTCL.