gebhart/patrepeval huggingface dataset:
Fabrication conditions and superconducting properties of Ag-sheathed Bi-Sr-Ca-Cu-O tapes prepared by partial melting and slow cooling process (1993)

Ag-sheathed Bi2Sr2Ca1Cu2Ox(Bi-2212) tapes with various oxide superconductor core (SC-core) thicknesses, SC-core ratios (SC-core area to overall cross-sectional area), and tape configurations were prepared by a partial melting and slow cooling process. For single-core tapes the critical current density, Jc(core), for SC-core, increases with decreasing SC-core thickness, due to the highly aligned Bi-2212 grains, and the highest Jc(core) of 1.4×105 A/cm2 at 4.2 K in 10 T is achieved at a core thickness of 15 μm. Furthermore, the Jc(core) increases with increasing SC-core ratio (i.e., with decreasing Ag-sheath thickness). From the practical point of view, high Jc(overall) as well as high critical current (Ic) is more important than Jc(core). This requirement is attained by the double-tube method, which shows the highest Jc(overall) value of 3.0×104 A/cm2 at 4.2 K in 10 T. In the tape fabrication process, the slow heating rate just below the partial melting becomes important, because oxygen released from the SC-core during heating makes void swelling in the Ag sheath and leads to the degradation of Jc.
Photochemische Synthese von Carbazolen und Indolo[3, 2‐b]carbazolen (1975)

Abstract Zur Abgrenzung des präparativen Anwendungsbereiches der Carbazolsynthese durch Photocyclisierung von Di‐ und Triarylaminen wurde das photochemische Verhalten einiger substituierter Triarylamine 1 , N, N′‐Diphenyl‐p‐phenylendiamine 2 und N, N′‐Diphenylbenzidine 3 untersucht. Während Fluor‐ und Methoxy‐substituierte Triphenylamine mit befriedigender Ausbeute in die entsprechenden Carbazole umgewandelt werden, sind Diarylaminobiphenyle und N, N′‐Diphenylbenzidin‐Derivate photochemisch stabil. N, N′‐Diphenyl‐N, N′‐dimethyl‐p‐phenylendiamin 3 a und N, N, N′, N′‐Tetraphenyl‐p‐phenylendiamin 3 b lassen sich hingegen zu den entsprechenden Indolo [3, 2‐b] carbazolen 5 a und 5 b umsetzen.
On the Method for the Quantitative Separation of Nucleic Acid in Native Form from Photographic Gelatin (1982)

A method for the quantitative isolation of nucleic acid from photographic gelatin was studied. The method consists of two steps; one is hydrolysis of the gelatin backbone in which a proteolytic enzyme free from nucleases is employed and the other is adsorption chromatography with DEAF Sephadex A–50. In application lo some photographic gelatins the nucleic acid was satisfactorily isolated in about 75%, overall yield.
Introduction: Nietzsche And Proust? Nietzsche And Proust? (2001)

This book presents a comparative study of German philosopher Friedrich Nietzsche and French writer Marcel Proust in order to demonstrate the often striking affinities between two individuals who were in many ways exploring similar problems and developing parallel responses to them in the undoubtedly different, but in their cases overlapping, fields of philosophy and literature. This study explores the more substantial points of philosophical agreement between Proust and Nietzsche which they betray, including their perspectivism and postmodernity. It presents a reading of Nietzsche which attends to the eminently Proustian problematics of involuted temporality and involuntary memory, the experience of transcendence, and the status of ‘essences’.
Thermal transport across carbon nanotube-graphene covalent and van der Waals junctions (2015)

Carbon nanotubes and graphene are promising materials for thermal management applications due to their high thermal conductivities. However, their thermal properties are anisotropic, and the radial or cross-plane direction thermal conductivity is low. A 3D Carbon nanotube (CNT)-graphene structure has previously been proposed to address this limitation, and direct molecular dynamics simulations have been used to predict the associated thermal conductivity. In this work, by recognizing that thermal resistance primarily comes from CNT-graphene junctions, a simple network model of thermal transport in pillared graphene structure is developed. Using non-equilibrium molecular dynamics, the resistance across an individual CNT-graphene junction with sp2 covalent bonds is found to be around 6×10−11 m2K/W, which is significantly lower than typical values reported for planar interfaces between dissimilar materials. In contrast, the resistance across a van der Waals junction is about 4×10−8 m2K/W. Interestingly, when the CNT pillar length is small, the interfacial resistance of the sp2 covalent junction is found to decrease as the CNT pillar length decreases, suggesting the presence of coherence effects. To explain this intriguing trend, the junction thermal resistance is decomposed into interfacial region and boundary components, and it is found that while the boundary resistance has little dependence on the pillar length, the interfacial region resistance decreases as the pillar length decreases. This is explained by calculating the local phonon density of states (LDOS) of different regions near the boundary. The LDOS overlap between the interfacial region and the center region of CNT increases as the pillar length decreases, leading to the decrease of interfacial region resistance. The junction resistance Rj is eventually used in the network model to estimate the effective thermal conductivity, and the results agree well with direct MD simulation data, demonstrating the effectiveness of our model.
Preclinical Studies on the Mechanism of Action and the Anti-Lymphoma Activity of the Novel Anti-CD20 Antibody GA101 (2011)

GA101 is a novel glycoengineered Type II CD20 monoclonal antibody. When compared with rituximab, it mediates less complement-dependent cytotoxicity (CDC). As expected for a Type II antibody, GA101 appears not to act through CDC and is more potent than the Type I antibody rituximab in inducing cell death via nonclassical induction of apoptosis cytotoxicity, with more direct cytotoxicity and more antibody-dependent cell-mediated cytotoxicity. We evaluated the antitumor activity of GA101 against the human-transformed follicular lymphoma RL model in vivo in severe combined immunodeficient mice (SCID) mice. GA101 induced stronger inhibition of tumor growth than rituximab. Combination of GA101 with cyclophosphamide in vivo confirmed the superiority of GA101 over rituximab. Neutralizing the complement system with cobra venom factor partially impaired the antitumor activity of rituximab, but had no impact on the efficacy of GA101. In vitro GA101 more potently induced cell death of RL cells than rituximab. The expression of a limited number of genes was found to be induced by both antibodies after exposure in vitro. Among these, early growth response 1 and activation transcription factor 3 were confirmed to be increased at the protein level, suggesting a possible role of these proteins in the apoptotic signalling of anti-CD20 antibodies. These data imply that GA101 is superior to rituximab not only as a single agent, but also in combination with chemotherapy. These data suggest the presence of novel signalization pathways activated after exposure to anti-CD20 antibodies.
MATHEMATICAL MODELLING AND SOLUTION APPROACHES FOR PRODUCTION PLANNING IN A CHEMICAL INDUSTRY (2017)

This paper addresses a lot sizing problem in a Brazilian chemical industry where a product can be produced by more than one process, which can use different parallel machines and may even consume a wide range of raw materials. Moreover, most of the products are liquids and the inventories must be kept in a restricted number of storage tanks with a limited capacity. Hence, these two issues are barely addressed in the literature on lot sizing. The classical multi-level capacitated lot sizing problem was extended to address them and a mixed integer programming (MIP) formulation was developed to determine how many batches should be produced and in which tank products should be stored to meet the demands and minimize production costs. The results of computational experiments show that the commercial solver found poor quality solutions or could not find feasible solutions within one hour. Thus, we applied relaxand-fix and fix-and-optimize MIP based heuristics and we observed that these heuristics were able to obtain feasible solutions for more instances in shorter computational times and find better solutions than those obtained by the commercial solver to solve the proposed model.
An access control architecture for managing large-scale network applications (2004)

We describe an access control architecture that targets large-scale network management solutions and other systems where there are many securable objects arranged in a natural hierarchy and where user roles are primarily broken down along a parallel hierarchy. In contrast to typical hierarchical role-based access control (HRBAC) systems, this design is based on a non-hierarchical role model connecting user groups, operations, and objects and infers privilege inheritance from the object hierarchy. Furthermore, this design treats user groups and user administrative operations in the same way as application objects and operations, enabling administrative delegation to arbitrary granularity with the same implicit role inheritance. This enables key use cases for large organizations or application service providers by allowing a single application instance to be shared among multiple noncoordinating users with fully delegated user management. We discuss the use of this design in a Lucent Worldwide Services (LWS) service offering.
La escuela como instauradora de la ley en la trama edípica (2012)

El presente trabajo hace parte del “Proyecto Ubacyt 2011-2014: Actitudes de estudiantes universitarios de grado y de posgrado de la Facultad de Psicología de la Universidad de Buenos Aires respecto de la ética profesional”, dirigido por la Dra. Elizabeth B. Ormart. Como trabajadores de la educación sabemos que cuando un chico ingresa a la escuela se establece un interjuego de tres partes: la familia, el alumno y el docente; es en este espacio donde se ponen en juego los deseos, expectativas, temores y conflictos de cada uno. El objetivo del presente escrito es realizar un análisis sobre la función de la escuela como instauradora de la Ley en la constelación familiar.
Searchable Answer Generating Environment (SAGE): A Knowledge Management System for Searching for Experts in Florida (1999)

The need to acquire intellectual capital created the Knowledge Management (KM) movement, which aims to develop new practices and tools to capture knowledge. In-depth examination of current KM projects revealed the largest percent of KM projects attempting to create some kind of a knowledge repository. Current studies identify three types of knowledge repositories. One type of knowledge repository attempts to manage organizational knowledge by storing pointers to those who have specific knowledge within the organization. In this light, this paper discusses the development of the Searchable Answer Generating Environment (SAGE) application. The development of this application was funded through the NASA/Florida Minority
ESD Protection Reliability in 1&#x003BC;M CMOS Technologies (1986)

The use of graded drains and silicided diffusions are shown to severely degrade Electrostatic Protection circuits when compared to their performance with traditional processing technology. The impact of each of these process options on the protection circuit sizing and the particular failure modes observed are reported here.
MICROFLUIDIC FLOW-THROUGH REACTOR WITH ELECTROCHEMICAL SENSOR ARRAY FOR REAL-TIME PCR (2009)

We developed an integrated microfluidic flow-through EC-PCR (EC-PCR) microdevice for the concurrent DNA amplification, PCR products EC detection and PCR products quantification instead of the current available fluorescence detection scheme. The microfluidic flow-through EC-PCR microdevice was fabricated with the state-of-the-art microfabrication technology, by bonding a bottom glass substrate having a microelectrode array to a top glass cover having the microchannels made of PDMS material. Both the amplification of the target DNA sequence and the subsequent EC detection of the PCR products were carried out concurrently on the integrated device by real-time monitoring. The underlying principle of the microfluidic flow-through EC-PCR method was based on the changes of current signal of methylene blue (MB), which worked as an electrochemically active species DNA intercalator in the PCR mixture, during the amplification process at the extension phase. The results shown in this work indicated that the nucleic acid analysis could be performed in a fast thermal cycling and true real-time quantitative electrochemical detection. The signal variation trends of the EC detection and the fluorescence detection were the same in our verification measurements for both methods, which suggested that the EC detection method was feasible for this application.
A clock synchronization system with IEEE 1588&#x2013;2008 adapters over existing Gigabit Ethernet equipment (2010)

This paper presents an IEEE 1588-2008 adapter that provides existing Gigabit Ethernet equipment with the functionalities required to clock synchronization on the order of sub-microsecond. To compensate the time error caused by the queuing delays in the Gigabit Ethernet equipment, the adapter measures the residence time and runs the peer delay mechanism for the equipment. Major functional blocks including the clock synchronization cores, Media Access Controls (MACs), and frame buffers have been integrated into a 21 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> silicon chip in 0.18 μm CMOS process. Experimental results show that the end devices can be synchronized within ±20 ns by simply attaching the proposed IEEE 1588-2008 adapters to the ordinary switches that connects the end devices.
Comprehensive analysis of glycated human serum albumin tryptic peptides by off‐line liquid chromatography followed by MALDI analysis on a time‐of‐flight/curved field reflectron tandem mass spectrometer (2006)

Glycated peptides arising from in vivo digestion of glycated proteins, usually called advanced glycation end (AGE) product peptides, are biologically relevant compounds due to their reactivity towards circulating and tissue proteins. To investigate their structures, in vitro glycation of human serum albumin (HSA) has been performed and followed by enzymatic digestion. Using different MALDI based approaches the digestion products obtained have been compared with those arising from enzymatic digestion of the protein. Results obtained using 2,5-dihydroxybenzoic acid (DHB) indicate this as the most effective matrix, leading to an increase in the coverage of the glycated protein. Off-line microbore liquid chromatography prior to MALDI analysis reveals that 63% of the free amino groups amenable to glycation are modified. In addition, the same approach shows the co-presence of underivatised peptides. This indicates that, regardless of the high glucose concentration employed for HSA incubation, glycation does not go to completion. Tandem mass spectrometric data suggest that the collision induced dissociation of singly charged glycated peptides leads to specific fragmentation pathways related to the condensed glucose molecule. The specific neutral losses derived from the activated glycated peptides can be used as signature for establishing the occurrence of glycation processes.
A High-Performance FPGA-Based Image Feature Detector and Matcher Based on the FAST and BRIEF Algorithms (2015)

Image feature detection and matching is a fundamental operation in image processing. As the detected and matched features are used as input data for high-level computer vision algorithms, the matching accuracy directly influences the quality of the results of the whole computer vision system. Moreover, as the algorithms are frequently used as a part of a real-time processing pipeline, the speed at which the input image data are handled is also a concern. The paper proposes an embedded system architecture for feature detection and matching. The architecture implements the FAST feature detector and the BRIEF feature descriptor and is capable of establishing key point correspondences in the input image data stream coming from either an external sensor or memory at a speed of hundreds of frames per second, so that it can cope with most demanding applications. Moreover, the proposed design is highly flexible and configurable, and facilitates the trade-off between the processing speed and programmable logic resource utilization. All the designed hardware blocks are designed to use standard, widely adopted hardware interfaces based on the AMBA AXI4 interface protocol and are connected using an underlying direct memory access (DMA) architecture, enabling bottleneck-free inter-component data transfers.
Structure of the altromycin B (N7-guanine)-DNA adduct. A proposed prototypic DNA adduct structure for the pluramycin antitumor antibiotics (1993)

Altromycin B belongs to the pluramycin family of antitumor antibiotics, which also includes kidamycin, hedamycin, pluramycin, neopluramycin, DC92-B, and rubiflavin A. These potent antitumor compounds react with DNA in as yet imprecisely determined ways. In the present investigation, we have used gel electrophoresis methods in combination with nuclear magnetic resonance and mass spectrometry to determine the structure of the altromycin B-DNA adduct. High-resolution gel electrophoresis demonstrated that guanine was the reactive base, and N7 was implicated from experiments in which N7-deazaguanine was used in place of guanine in a strand breakage assay. Experiments using supercoiled DNA demonstrated that altromycin B and related drugs intercalated into DNA, which implicated this as a common mechanism for binding of the pluramycin antibiotics to DNA. The altromycin B-guanine adduct was isolated from calf thymus DNA after thermal depurination of the alkylated DNA. Mass spectrometry confirmed that altromycin alkylated DNA through guanine, and 1H- and 13C-NMR was used to confirm the covalent linkage sites between altromycin B and guanine. On the basis of these results, we propose that altromycin B first intercalates into DNA via a threading mechanism, reminiscent of nogalamycin, to insert the disaccharide into the minor groove and position the epoxide in the major groove in proximity to N7 of guanine. Nucleophilic attack from N7 of guanine leads to an acid-catalyzed opening of the epoxide, resulting in the altromycin B-DNA adduct. On the basis of these results, a general mechanism for the interaction of the pluramycin family of antibiotics with DNA is proposed.
Rolled-up nanotech on polymers: from basic perception to self-propelled catalytic microengines (2011)

In this tutorial review we describe the recent progress on catalytic microtubular engines fabricated by rolled-up nanotech on polymers. We summarize the technical aspects of the technology and the basic principles that cause the catalytic microengines to self-propel in fuel solutions. The control over speed, directionality and interactions of the microengines to perform tasks such as cargo transportation is also discussed. We compare this technology to other fabrication techniques of catalytic micro-/nanomotors and outline challenges and opportunities for such engines in future studies. Since rolled-up nanotech on polymers can easily integrate almost any type of inorganic material, huge potential and advanced performance such as high speed, cargo delivery, motion control, and dynamic assembly are foreseen--ultimately promising a practical way to construct versatile and intelligent catalytic tubular microrobots.
Computer-aided planning of reconstructive surgery of the innominate bone: Automated correction proposals (2007)

A highly automated, computer-aided approach to surgical planning for pelvic bone defects was developed and sample applications demonstrated. Validation results for healthy acetabula were superior to those obtained in real surgery. The generated virtual correction proposals can be used as targets in surgical planning and cup navigation applications, or in the design of customized implants with complex shapes.
Atmospheric transmission windows for high energy short pulse lasers (2003)

The US Navy is exploring the feasibility of using a high energy laser weapon as a ship-borne self-defense system against sea-skimming cruise missile attacks. Since the attenuation of laser energy by the atmosphere is the highest at low altitudes and varies with frequency, the selection of appropriate wavelengths becomes critical for a laser weapon to be effective. A high energy free electron laser (FEL) is suitable for employment in the envisaged role because it can be designed to operate at any desired frequency and, to a degree, is tunable in operation. This study aims to determine the optimal atmospheric windows for high energy, pico second, short pulse lasers. Computer simulations were carried out by convolving a pulse spectrum with the transmission spectrum and the absorption coefficient from the MODTRAN and FASCODE atmospheric codes. Transmission spectrum and absorption coefficient plots were compared to find the range of suitable wavelengths that give good transmittance and low absorption coefficient values.
Control system design for visual based indoor inspection helicopter (2010)

This paper is on control system design for visual based indoor inspection helicopters. For the indoor inspection system for large structures, there are some cases where it is difficult for humans to work with. This paper introduces indoor inspection helicopter system with only inspection camera and prism for position sensing as payload. The control system is designed to help the operator of the inspection system to control the helicopter to designated position without much practice. The cases of the control by experienced and novice operators are compared and results show that the system has feasibility for indoor inspection system to be used by any kind of users.
Detection of Δ9‐tetrahydrocannabinolic acid A in human urine and blood serum by LC‐MS/MS (2007)

Delta9-tetrahydrocannabinolic acid A (Delta9-THCA-A) is the precursor of Delta9-tetrahydrocannabinol (Delta9-THC) in hemp plants. During smoking, the non-psychoactive Delta9-THCA-A is converted to Delta9-THC, the main psychoactive component of marihuana and hashish. Although the decarboxylation of Delta9-THCA-A to Delta9-THC was assumed to be complete--which means that no Delta9-THCA-A should be detectable in urine and blood serum of cannabis consumers--we found Delta9-THCA-A in the urine and blood serum samples collected from police controls of drivers suspected for driving under the influence of drugs (DUID). For LC-MS/MS analysis, urine and blood serum samples were prepared by solid-phase extraction. Analysis was performed with a phenylhexyl column using gradient elution with acetonitrile. For detection of Delta9-THCA-A, the mass spectrometer (MS) (SCIEX API 365 triple-quadrupole MS with TurboIonSpray source) was operated in the multiple reaction monitoring (MRM) mode using the following transitions: m/z357 --> 313, m/z357 --> 245 and m/z357 --> 191. Delta9-THCA-A could be detected in the urine and blood serum samples of several cannabis consumers in concentrations of up to 10.8 ng/ml in urine and 14.8 ng/ml in serum. The concentration of Delta9-THCA-A was below the Delta9-THC concentration in most serum samples, resulting in molar ratios of Delta9-THCA-A/Delta9-THC of approximately 5.0-18.6%. Only in one case, where a short elapsed time between the last intake and blood sampling is assumed, the molar ratio was 18.6% in the serum. This indicates differences in elimination kinetics, which need to be investigated in detail.