gebhart/patrepeval huggingface dataset:
La erosión del suelo (1994)

Despite the ecological significance of the mutualistic relationship between Symbiodiniaceae and reef-building corals, the molecular interactions during establishment of this relationship are not well understood. This is particularly true of the transcriptional changes that occur in the symbiont. In the current study, a dual RNA-sequencing approach was used to better understand transcriptional changes on both sides of the coral-symbiont interaction during the colonization of Acropora tenuis by a compatible Symbiodiniaceae strain (Cladocopium goreaui; ITS2 type C1). Comparison of transcript levels of the in hospite symbiont 3, 12, 48 and 72 hr after exposure to those of the same strain in culture revealed that extensive and generalized down-regulation of symbiont gene expression occurred during the infection process. Included in this "symbiosis-derived transcriptional repression" were a range of stress response and immune-related genes. In contrast, a suite of symbiont genes implicated in metabolism was upregulated in the symbiotic state. The coral data support the hypothesis that immune-suppression and arrest of phagosome maturation play important roles during the establishment of compatible symbioses, and additionally imply the involvement of some SCRiP family members in the colonization process. Consistent with previous ecological studies, the transcriptomic data suggest that active translocation of metabolites to the host may begin early in the colonization process, and thus that the mutualistic relationship can be established at the larval stage. This dual RNA-sequencing study provides insights into the transcriptomic remodelling that occurs in C. goreaui during transition to a symbiotic lifestyle and the novel coral genes implicated in symbiosis.
Heparin Concentrations Correlated To The Activated Whole Blood Clotting Time (Act) During Extracorporeal Circulation (1981)

Heparin levels and ACT were followed during open heart surgery in lo patients. Heparin was assayed by an amidolytic method using substrate S-2222. ACT was determined with an automated method using celite and glass beads as activators of coagulation. Neither the hemodilution nor the depletion of platelets observed during extracorporeal circulation seemed to influence the ACT. An excellent correlation between the ACT and the actual heparin level was found in each patient with coefficients of correlation ranging from 0.73 – 0.97. A slightly better correlation was noticed for values of ACT below 600 seconds. It was concluded that the ACT is a valuable and reliable tool in control of heparinisation during open heart surgery.
Feasibility study of electricity generation from discard coal (2015)

Copyright: 2015 SAIMM. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, please consult the publisher's website. The definitive version of the work is published in Journal of the SA Institute of Mining and Metallurgy, vol. 115, pp 153-165
Evaluation of the current knowledge limitations in breast cancer research: a gap analysis (2008)

Through recommendations to address these gaps with future research, the long-term benefits to patients will include: better estimation of risk in families with breast cancer and strategies to reduce risk; better prediction of drug response and patient prognosis; improved tailoring of treatments to patient subgroups and development of new therapeutic approaches; earlier initiation of treatment; more effective use of resources for screening populations; and an enhanced experience for people with or at risk of breast cancer and their families. The challenge to funding bodies and researchers in all disciplines is to focus on these gaps and to drive advances in knowledge into improvements in patient care.
Silicon Switches of Marketed Drugs (2006)

The application of organosilicon chemistry is a strategy to develop best in class drugs applied to targets that have been validated as tractable and drug-able. Silicon switches of known drugs have been synthesised and evaluated in biological assay systems then compared to their marketed all-carbon counterparts. Recent examples include the silicon switches of drugs haloperidol, fexofenadine, bexarotene and venlafaxine.
Spontaneous emission of localized excitons in InGaN single and multiquantum well structures (1996)

Emission mechanisms of InGaN single quantum well blue and green light emitting diodes and multiquantum well structures were investigated by means of modulation spectroscopy. Their static electroluminescence (EL) peak was assigned to the recombination of excitons localized at certain potential minima in the quantum well. The blueshift of the EL peak caused by the increase of the driving current was explained by combined effects of the quantum-confinement Stark effect and band filling of the localized states by excitons.
TEM Investigation of Counter-Electrode Structure in Ta Capacitors (2005)

Journal Article TEM Investigation of Counter-Electrode Structure in Ta Capacitors Get access P A Carvalho, P A Carvalho Universidade Técnica de Lisboa, Portugal Search for other works by this author on: Oxford Academic Google Scholar D Dias, D Dias Universidade Técnica de Lisboa, Portugal Search for other works by this author on: Oxford Academic Google Scholar A C Ferro, A C Ferro Universidade Técnica de Lisboa, Portugal Search for other works by this author on: Oxford Academic Google Scholar W Lohwasser W Lohwasser EPCOS, Portugal Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 11, Issue S02, 1 August 2005, Pages 2098–2099, https://doi.org/10.1017/S1431927605510134 Published: 01 August 2005
Hash codes for the identification and classification of molecular structure elements (1994)

Abstract A set of algorithms is presented which establish the topological identity of atoms, bonds, molecules, and ensembles of molecules from a basic connection table. The computationally inexpensive result is a fixed‐length hash code which is suited for database applications and structure manipulation programs. The degree of differentiation between structural entities is adjusted easily for stereocenters, isotope labeling, atomic charges, and ionization locations or other properties. Special algorithms are presented which deal with problematic cases of uniform atomic environments. A number of practical applications demonstrate the usefulness of these hash codes. © 1994 by John Wiley & Sons, Inc.
Redactable Blockchain - or - Rewriting History in Bitcoin and Friends. (2016)

We put forward a new framework that makes it possible to re-write or compress content of any number of blocks in decentralized services exploiting blockchain technology. As we argue, there are several reasons to prefer an editable blockchain, spanning from necessity to remove inappropriate content and possibility to support applications requiring re-writable storage, to the right to be forgotten. Our approach generically leverages so-called chameleon hash functions (Krawczyk and Rabin, NDSS '00), which allow determining hash collisions efficiently, given a secret trapdoor information. We detail how to integrate a chameleon hash function in virtually any blockchain-based technology, for both cases where power of redacting blockchain content is in hands of a single trusted entity and where such a capability is distributed among several distrustful parties (as is case with Bitcoin). We also report on a proof-of-concept implementation of a redactable blockchain, building on top of Nakamoto's Bitcoin core. The prototype only requires minimal changes to way current client software interprets information stored in blockchain and to current blockchain, block, or transaction structures. Moreover, our experiments show that overhead imposed by a redactable blockchain is small compared to case of an immutable one.
X-ray crystal structure and molecular dynamics of (indenyl)bis(ethylene)rhodium(I): 500-MHz NMR spectra and EHMO calculations (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTX-ray crystal structure and molecular dynamics of (indenyl)bis(ethylene)rhodium(I): 500-MHz NMR spectra and EHMO calculationsMichael. Mlekuz, Peter. Bougeard, Brian G. Sayer, Michael J. McGlinchey, Charles A. Rodger, Melvyn Rowen. Churchill, Joseph W. Ziller, Sung Kwon. Kang, and Thomas A. AlbrightCite this: Organometallics 1986, 5, 8, 1656–1663Publication Date (Print):August 1, 1986Publication History Published online1 May 2002Published inissue 1 August 1986https://pubs.acs.org/doi/10.1021/om00139a024https://doi.org/10.1021/om00139a024research-articleACS PublicationsRequest reuse permissionsArticle Views110Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Coherent broadband microwave spectroscopy using picosecond optoelectronic antennas (1989)

We describe coherent microwave transient spectroscopy experiments using picosecond optoelectronic integrated antennas. The effectiveness of the experimental setup for the measurement of the loss and dispersion properties of materials in the 10–125 GHz range is characterized using microwave filters of predictable behavior. We also present measurements of the absorption coefficient and refractive index of fused silica over this frequency band.
The Growth-inhibitory Effect of the Enterococcus faecalis Bacteriocin Encoded by pADl Extends to the Oral Streptococci (1990)

Many strains of Enterococcus faecalis, a normal inhabitant of the oral cavity, elaborate a plasmid-encoded bacteriocin. The growth-inhibitory effect of this bacteriocin was observed to extend to a variety of pathogenic oral streptococci, including those that play a major role in tooth surface colonization and caries formation. These results suggest that transient colonization by bacteriocin-producing E. faecalis may effect shifts in oral colonization by susceptible organisms and that bacteriocin-producing E. faecalis may be a candidate for application in strain replacement therapy.
A Comparison of Valproate with Carbamazepine for the Treatment of Complex Partial Seizures and Secondarily Generalized Tonic–Clonic Seizures in Adults (1992)

Valproate is as effective as carbamazepine for the treatment of generalized tonic-clonic seizures, but carbamazepine provides better control of complex partial seizures and has fewer long-term adverse effects.
Real-time 3D image guided patient positioning in radiation therapy (2006)

Patient positioning in modern radiotherapy is becoming far more important because a small positioning error may result in missing target and irradiating normal tissues in treatment of small lesions. Clinical outcome of radiotherapy can potentially be improved by increasing the precision of tumor localization and dose delivery during the treatment. In this paper an accurate and precise patient positioning system has been achieved through alignment of real-time three dimensional (3D) surface images with a reference surface image. The real-time 3D surface is captured using a state-of-art 3D stereovision system, and then is matched with the pre-defined reference image generated from treatment planning data. Positioning parameters are calculated by automatically aligning the real-time surface and the reference surface via a modified Iterative Closest Points (ICP) algorithm. Results from phantom experiments and clinical applications demonstrated the excellent efficacy of <2 minutes and the desired accuracy and precision of <1 mm in isocenter shifts and of <1 degree in rotations.
A high-fidelity decimator chip for the measurement of sigma-delta modulator performance (1995)

This paper reports on results from the algorithmic design and simulation of a two-path polyphase decimation filter with 24-bit accuracy over the frequency range from dc to 15.2 kHz. The filter is suited for very high precision data conversion and measurement applications. The device reported in this paper has been designed for use with a fourth-order, single-loop, /spl Sigma//spl Delta/ modulator running at 4096 kHz. Results of floating and fixed-point simulations, architectural design, comparative bit-level simulations and silicon implementation of the decimator are also reported, together with a sample baseband measurement of a fourth-order modulator.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Selective Cyclooxygenase‐2 Inhibitor May Impair Bone Healing Around Titanium Implants in Rats (2006)

Meloxicam may negatively influence bone healing in the cortical and cancellous bone around titanium implants inserted in rats after continuous administration.
Practical circular-polarization-maintaining optical fiber (1997)

The author describes a new idea for making circular-polarization-maintaining optical fiber with an existing fabrication technique. The method simply requires one to spin at a constant rate a special preform consisting of only one off-axis stress-applying element in addition to the on-axis core. Measurements taken with such a fiber specimen verify the existence of circular eigenmodes, the ease of joining or splicing two fiber segments, the tolerance to macrobending with a small radius, etc. Good agreement exists between the experimental data and the theoretical analysis. Prospective applications are discussed.
Radiation Sensor Compatible With Standard CMOS Technology (2009)

This paper presents a gamma radiation dosimeter built in a standard 0.35 mum CMOS technology. The dosimeter, which occupies 300 times 150 mum times mum of silicon area, gives a digital output signal of frequency proportional to the total dose. Experimental results up to 1.5 Mrads are presented. Measured low dose radiation responsivity is 84.7 Hz/Krad and sensitivity to temperature and supply voltage are 1.43 kHz/degC and 20.9 kHz/V, respectively.
Acyclovir prevents reactivation of herpes simplex labialis in skiers (1988)

To determine the effectiveness of an antiviral to prevent herpes labialis during a brief, high-risk circumstance, 147 persons with a history of sun-induced recurrences were treated prophylactically with oral acyclovir or matching placebo and were observed during their ski holidays. Five (7%) of 75 acyclovir-treated subjects developed lesions compared with 19 (26%) of 72 persons in the placebo group. (<i>JAMA</i>1988;260:1597-1599)
The Injured and Regenerating Nervous System (2011)

Understanding restricted functional recovery and designing efficient treatments to alleviate dysfunction after injury of the nervous system remain major challenges in neuroscience and medicine. Numerous molecules of potential significance in neural repair have been identified in vitro, but only few of these have proved to be of major importance in vivo up to now. Among the molecules involved in regeneration are several members of the immunoglobulin superfamily, most notably the neural cell adhesion molecules L1, its close homologue CHL1, and NCAM and, in particular, its polysialic acid glycan moiety. Sufficient evidence is now available to justify the statement that these molecules are major players not only in nervous system development but also in the adult during neural repair and synaptic plasticity. Importantly, insights into the functions of these molecules in promoting or inhibiting functional recovery have allowed the design and assessment of therapeutic approaches in animal models of central nervous system injury that could prove to be applicable in clinical settings.
GNSS Shadow Matching: The Challenges Ahead (2015)

GNSS shadow matching is a new technique that uses 3D mapping to improve positioning accuracy in dense urban areas from tens of meters to within five meters, potentially less. This paper presents the first comprehensive review of shadow matching’s error sources and proposes a program of research and development to take the technology from proof of concept to a robust, reliable and accurate urban positioning product. A summary of the state of the art is also included. Error sources in shadow matching may be divided into six categories: initialization, modelling, propagation, environmental complexity, observation, and algorithm approximations. Performance is also affected by the environmental geometry and it is sometimes necessary to handle solution ambiguity. For each error source, the cause and how it impacts the position solution is explained. Examples are presented, where available, and improvements to the shadow-matching algorithms to mitigate each error are proposed. Methods of accommodating quality control within shadow matching are then proposed, including uncertainty determination, ambiguity detection, and outlier detection. This is followed by a discussion of how shadow matching could be integrated with conventional ranging-based GNSS and other navigation and positioning technologies. This includes a brief review of methods to enhance ranging-based GNSS using 3D mapping. Finally, the practical engineering challenges of shadow matching are assessed, including the system architecture, efficient GNSS signal prediction and the acquisition of 3D mapping data.
Pilon Fractures (2000)

One hundred seven pilon fractures in 107 patients were treated according to a staged prospective protocol. All pilon fractures were stabilized immediately by the application of calcaneal traction. Open fractures or fractures in patients with multiple injuries were stabilized with traveling traction that was applied in the operating room. A distraction computed tomography scan was obtained before definitive treatment. Treatment groups were based on the degree of soft tissue compromise. Forty-one patients with Tscherne Grade 0 or Grade I injuries underwent open reduction and internal fixation (open plating) using contemporary techniques and low-profile implants. Sixty-four patients with Tscherne Grade II and Grade III closed injuries and all patients with open fractures underwent definitive treatment with limited open reduction and stabilization using small wire circular external fixators. Clinical and radiographic evaluations were performed at an average 4.9 years after injury. For all fracture types (AO classification), 81% of the patients who were treated with external fixation and 75% of the patients who were treated with open plating had good or excellent results. For severe fracture patterns (Type C), patients in both groups had significantly poorer results than patients with Types A and B fractures. The patients in the open plating group had a significantly higher rate of nonunion, malunion, and severe wound complications compared with the patients who received external fixation for Type C fracture patterns. Because of the increased incidence of bony and soft tissue complications when treating open or closed Type C fractures, use of limited exposures and stabilization with small wire circular external fixators is recommended.
More than electronic toll booths: Singapore’s electronic road pricing innovation (2005)

This paper explores the dynamics of the Electronic Road Pricing (ERP) innovation in Singapore, tracing its implementation to subsequent diffusion to delineate the links between technology and society. The ERP system, introduced in 1998, is an elaborate and sophisticated toll collecting system using ICTs to regulate road usage. We use the actor–network theory (ANT) as a conceptual tool to analyse the dynamics of this innovation. Through a detailed examination of both human and non‐human actors, we are able to analyse how interests of heterogeneous members of a societal network can be aligned to introduce a technological innovation. In the process, we have observed issues arising from the differential power relationship that exists between road users and government planners as well as the integration of the social and technical aspects of this emerging socio‐technological system. As an emergent technology, the ERP innovation system reflects the social morphology of Singapore as it plays out its part in the making of this nascent nation.
Application specific DSP at SGS Thomson (2003)

The author describes the first level of customization, wherein an application-specific digital signal processor (AS DSP) is built around an existing DSP core chip. A DSP core is a standard DSP where all input/output pads, buffers, and associated circuitry have been removed and replaced by smaller structures and specific functions dedicated to testability. This operation saves a large amount of silicon area that can be better used to implement clever and smart functions. This core is included in a library with the complete environment and resources to be user friendly on a standard engineering workstation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Effects of the compensation level on the carrier lifetime of crystalline silicon (2008)

This study focuses on the evolution of the carrier lifetime with the compensation level in crystalline silicon. Especially we show that an increase in the compensation level reduces the recombination strength of doping species and of some metal impurities. These theoretical results are confirmed by the chemical and electrical characterizations of strongly compensated multicrystalline silicon wafers. These results are of paramount importance since an accurate control of the compensation level can lead to strong improvements in silicon solar cells efficiencies.
Deletion in the Gene for the Low-Density-Lipoprotein Receptor in a Majority of French Canadians with Familial Hypercholesterolemia (1987)

We found a large deletion (more than 10 kilobases) in the gene for the low-density-lipoprotein receptor in 63 percent of French Canadians with heterozygous familial hypercholesterolemia. The deletion also occurred in homozygous form in four of seven French Canadian homozygotes. The deletion removes the promoter and first exon of the gene, and it abolishes the production of messenger RNA for the low-density-lipoprotein receptor. The high frequency of this mutation is presumably related to a founder effect among the 8000 ancestors of present-day French Canadians, who have had relatively little cross-breeding with groups of other national origins. This deletion has not been observed in any other ethnic group. It can be detected by analysis of genomic DNA from blood leukocytes, thus allowing direct diagnosis of familial hypercholesterolemia in a majority of affected French Canadians.
Characterizing and Predicting TCP Throughput on the Wide Area Network (2005)

DualPats exploits the strong correlation between TCP throughput and flow size, and the statistical stability of Internet path characteristics to accurately predict the TCP throughput of large transfers using active probing. We propose additional mechanisms to explain the correlation, and then analyze why traditional TCP benchmarking fails to predict the throughput of large transfers well. We characterize stability and develop a dynamic sampling rate adjustment algorithm so that we probe a path based on its stability. Our analysis, design, and evaluation is based on a large-scale measurement study.