gebhart/patrepeval huggingface dataset:
Anticonvulsants. 1. Alkoxymethyl derivatives of barbiturates and diphenylhydantoin (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnticonvulsants. 1. Alkoxymethyl derivatives of barbiturates and diphenylhydantoinJulius A. Vida, Carlos M. Samour, and John F. ReinhardCite this: J. Med. Chem. 1971, 14, 3, 187–189Publication Date (Print):March 1, 1971Publication History Published online1 May 2002Published inissue 1 March 1971https://pubs.acs.org/doi/10.1021/jm00285a002https://doi.org/10.1021/jm00285a002research-articleACS PublicationsRequest reuse permissionsArticle Views109Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Eosinophils and C4 predict clinical failure of combination immunotherapy with very low dose subcutaneous interleukin-2 and interferon in renal cell carcinoma patients. (2000)

As far as concerns C4, its negative predictive value could be related to the fact that it is an indirect index of macrophage activation; thus, even though macrophages release substances with antitumor activity, they can also stimulate the release of sIL-2R, which may compete for exogenous IL-2. Some authors have postulated that macrophages may even stimulate tumor cell growth, or impair NK activity. Despite a great amount of uncertainty concerning the role of eosinophils, in our study, blood eosinophilia predicts a poor response to immunotherapy in patients with advanced RCC, thus supporting previous observations from our own group.
v-rel- and c-rel-protein complexes bind to the NF-kappa B site in vitro. (1992)

Previous work by others has revealed homology between the rel oncogene and the transcription factor NF-kappa B. Further, in vitro-translated v-rel protein and c-rel protein are able to bind to an oligonucleotide containing the kappa B binding site. Unlike the in vitro-translated product, cellular Rel protein exists in high molecular weight complexes with several other proteins. In this report we show that immunopurified cellular complexes containing the v-rel protein and/or the c-rel protein are also able to bind to an oligonucleotide containing the kappa B site. These cellular complexes are heterogeneous in size, and all sizes appeared to have binding activity. UV cross-linking demonstrated that the Rel proteins themselves were bound to the DNA. Thus it is likely that the Rel proteins play a direct role in transcriptional regulation.
Feature selection for learning versatile manipulation skills based on observed and desired trajectories (2017)

For a manipulation skill to be applicable to a wide range of scenarios, it must generalize between different objects and object configurations. Robots should therefore learn skills that adapt to features describing the objects being manipulated. Most of these object features will however be irrelevant for generalizing the skill and, hence, the robot should select a small set of relevant features for adapting the skill. We use a framework for learning versatile manipulation skills that adapt to a sparse set of object features. Skills are initially learned from demonstrations and subsequently improved using reinforcement learning. The robot also learns a meta prior over the features' relevances to guide the feature selection process. In this paper, we explore using either desired trajectories or observed trajectories for selecting the relevant features. The framework was evaluated on placing, tilting, and wiping tasks. The evaluations showed that using the desired trajectories to select the relevant features lead to better skill learning performance.
Infra-red homodyne receiver with acousto-optically controlled local oscillator (1983)

A homodyne receiver for 10 μm radiation has been built, based on the phase-locked-loop principle. Fast frequency control of the local CO2 laser is achieved by an acoustooptic frequency shifter. Demodulation of a 100 Mbit/s phase-modulated input signal has been demonstrated.
Long‐term outcome of adalimumab therapy for ulcerative colitis with intolerance or lost response to infliximab: a single‐centre experience (2008)

Adalimumab is well-tolerated and may be effective in maintaining clinical remission in a subgroup of patients with ulcerative colitis and lost response or intolerance to infliximab, potentially avoiding colectomy in about half of the patients.
Topographic mapping from interferometric synthetic aperture radar observations (1985)

The production of high-resolution topographic maps derived from interferometric synthetic aperture radar observations of the Earth is reported. Topographic maps are typically determined from stereo-pair optical photographs. Vertical relief causes the same terrain to appear in a slightly different projection for differing look angles, and this shift in appearance is interpreted in terms of the height of the terrain. The radar interferometric approach is related to the stereo technique in that the terrain is viewed at two different angles; however, in this case, the angular separation of the antennas is extremely small, on the order of a milliradian or less, as compared to tens of degrees for the optical case. Thus, the geometrical distortion and subsequent rectification correction algorithms are much less severe in the reduction of interferometric data.
Wireless phone threat assessment for aircraft communication and navigation radios (2006)

Emissions in aircraft communication and navigation bands are measured for the latest generation of wireless phones. The two wireless technologies considered, GSM/GPRS and CDMA2000, are the latest available to general consumers in the U.S. A base-station simulator is used to control the phones. The measurements are conducted using reverberation chambers, and the results are compared against FCC and aircraft installed equipment emission limits. The results are also compared against baseline emissions from laptop computers and personal digital assistant devices that are currently allowed to operate on aircraft.
A CMOS fully balanced four-terminal floating nullor (2002)

This paper presents design and implementation of a CMOS fully balanced realization of the four-terminal floating nullor (FTFN). The proposed fully balanced FTFN (FBFTFN) is an essential building block for implementing fully balanced architectures of both voltage and current-mode analog CMOS integrated circuits (ICs). A low-power class AB CMOS realization of the proposed circuit is fabricated in a 1.2-/spl mu/m technology. The proposed circuit has numerous applications. Several applications including fully balanced amplifiers, filters, and sinusoidal oscillators are presented. All proposed design techniques and circuits are experimentally verified.
The Mechanism of Action of Angiostatin: Can You Teach an Old Dog New Tricks? (2002)

What is angiostatin? In 1994, Folkman and colleagues published a landmark paper describing anti-tumor effects in mice with a purified fragment of plasminogen they named angiostatin (1). Although many papers have been published describing activities of cryptic polypeptides derived from plasminogen fragments, this was the first report which associated plasminogen kringles 1-4 as a suppressor of metastasis development. This review will describe what is known about the mechanism of action of angiostatin from the current literature.
Acute myeloblastic leukemic cells acquire cellular cytotoxicity under genotoxic stress: implication of granzyme B and perforin (2000)

Granzyme B (GrB) and perforin (PFN) are the major components of cytoplasmic granules contained in immune cellular effectors. The granule secretory pathway is one of the mechanisms by which these cells exert their cellular cytotoxicity. Recently, it has been reported that GrB and PFN are also present in circulating hemopoietic CD34+ progenitor cells mobilized by chemotherapy and granulocyte-colony stimulating factor, whereas these proteins are undetected in steady-state peripheral CD34+ cells. In this study, we hypothesized that anticancer agents may increase GrB and PFN expression in immature myeloid leukemic cells and that these treated leukemic cells become cellular effectors through a granule-dependent mechanism. Our results show that KG1a, HEL, and TF-1 CD34+acute myeloblastic leukemia cells expressed both GrB and PFN. Moreover, ionizing radiation, aracytine, and etoposide not only increase GrB and PFN expression but also conferred potent cellular cytotoxicity to these cells toward various cellular targets. Cellular cytotoxicity required cell-cell contact, was not influenced by anti-tumor necrosis factor α or anti-Fas blocking antibodies, and was abrogated by GrB inhibitors or antisense. These results suggest that, when exposed to genotoxic agents, immature leukemic cells acquire potent GrB- and PFN-dependent cellular cytotoxicity that can be potentially directed against normal residual myeloid progenitors or immune effectors.
Laser-induced breakdown spectroscopy: A new tool for materials analysis (2003)

The laser-induced breakdown spectroscopy (LIBS) technique has shown in recent years its great potential for rapid quantitative analysis of materials. In this paper, we will present work carried out in our laboratory that has addressed the influence of the main experimental parameters on the quality of LIBS measurements. In particular, we will discuss new approaches (double-pulse mode, ultrashort laser pulse, mixed–wavelength pulse, Échelle spectrometer, etc.) and their impact on the sensitivity and the accuracy of the LIBS technique. Finally, we will describe our application of LIBS to the analysis of liquid samples.
Cartilage calcification of the ankle joint is associated with osteoarthritis in the general population (2018)

The prevalence of AJ CC in the general population is much higher than expected. The relationship between the amount of AJ CC and OA, independent of the donors' age and BMI, indicates that CC may play a causative role in the development of OA in ankles.
Reaction of Methylsilanols with Hydrated Silica Surfaces: The Hydrolysis of Trichloro-, Dichloro-, and Monochloromethylsilanes and the Effects of Curing (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of Methylsilanols with Hydrated Silica Surfaces: The Hydrolysis of Trichloro-, Dichloro-, and Monochloromethylsilanes and the Effects of CuringC. P. Tripp and M. L. HairCite this: Langmuir 1995, 11, 1, 149–155Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://pubs.acs.org/doi/10.1021/la00001a027https://doi.org/10.1021/la00001a027research-articleACS PublicationsRequest reuse permissionsArticle Views1212Altmetric-Citations150LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
3D Slit Scanning with Planar Constraints<sup>★</sup> (2008)

Abstract We present a planarity constraint and a novel three‐dimensional (3D) point reconstruction algorithm for a multiview laser range slit scanner. The constraint is based on the fact that all observed points on a projected laser line lie on the same plane of laser light in 3D. The parameters of the plane of laser light linearly parametrize a homography between a pair of images of the laser points. This homography can be recovered from point correspondences derived from epipolar geometry. The use of the planar constraint reduces outliers in the reconstruction and allows for the reconstruction of points seen in only one view. We derive an optimal reconstruction of points subject to the planar constraint and compare the accuracy to the suboptimal approach in prior work. We also construct a catadioptric stereo rig with high quality optical components to remove error due to camera synchronization and non‐uniform laser projection. The reconstruction results are compared to prior work that uses inexpensive optics and two cameras.
Quasi-phase-matched frequency doubling over 5 mm in periodically poled polymer waveguide (1990)

Quasi-phase-matched second harmonic generation from 1340 to 670 nm with a quasi-phase-matching length of 5 mm is demonstrated in a periodically poled polymer waveguide containing a nonlinear optical polymer. Angle, wavelength and temperature tuning are used to obtain independent measures of the quasi-phase-matching length, and those factors limiting the quasi-phase-matching length are indicated.
Invertibility and transitivity analysis for nonrigid image registration (2003)

The <i>Journal of Electronic Imaging</i> (JEI), copublished bimonthly with the Society for Imaging Science and Technology, publishes peer-reviewed papers that cover research and applications in all areas of electronic imaging science and technology.
Epigallocatechin Gallate (EGCG) Is the Most Effective Cancer Chemopreventive Polyphenol in Green Tea (2012)

Green tea is a popular drink consumed daily by millions of people around the world. Previous studies have shown that some polyphenol compounds from green tea possess anticancer activities. However, systemic evaluation was limited. In this study, we determined the cancer chemopreventive potentials of 10 representative polyphenols (caffeic acid, CA; gallic acid, GA; catechin, C; epicatechin, EC; gallocatechin, GC; catechin gallate, CG; gallocatechin gallate, GCG; epicatechin gallate, ECG; epigallocatechin, EGC; and epigallocatechin gallate, EGCG), and explored their structure-activity relationship. The effect of the 10 polyphenol compounds on the proliferation of HCT-116 and SW-480 human colorectal cancer cells was evaluated using an MTS assay. Cell cycle distribution and apoptotic effects were analyzed by flow cytometry after staining with propidium iodide (PI)/RNase or annexin V/PI. Among the 10 polyphenols, EGCG showed the most potent antiproliferative effects, and significantly induced cell cycle arrest in the G1 phase and cell apoptosis. When the relationship between chemical structure and anticancer activity was examined, C and EC did not show antiproliferative effects, and GA showed some antiproliferative effects. When C and EC esterified with GA to produce CG and ECG, the antiproliferative effects were increased significantly. A similar relationship was found between EGC and EGCG. The gallic acid group significantly enhanced catechin's anticancer potential. This property could be utilized in future semi-synthesis of flavonoid derivatives to develop novel anticancer agents.
Lysergic acid and quinidine analogs. 2-(o-Acylaminophenethyl)piperidines (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLysergic acid and quinidine analogs. 2-(o-Acylaminophenethyl)piperidinesStanley J. Dykstra, Joseph L. Minielli, John E. Lawson, Hugh C. Ferguson, and Kendrick W. DunganCite this: J. Med. Chem. 1973, 16, 9, 1015–1020Publication Date (Print):September 1, 1973Publication History Published online1 May 2002Published inissue 1 September 1973https://pubs.acs.org/doi/10.1021/jm00267a012https://doi.org/10.1021/jm00267a012research-articleACS PublicationsRequest reuse permissionsArticle Views167Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Identification of Autonomously Replicating Sequence (ARS) Elements in Eukaryotic Cells (1997)

Autonomously replicating sequence (ARS) elements were first identified in the budding yeast Saccharomyces cerevisiae as chromosomal DNA fragments that promoted high frequency of transformation and extrachromosomal maintenance of plasmid DNA. These specific sequence elements were subsequently shown to function as origins of DNA replication. Detailed analysis of the structure and function of ARS elements has been limited largely to S. cerevisiae and more recently the fission yeast Schizosaccharomyces pombe. Characterization of ARS activity in other eukaryotes is far less complete. Here we describe the ARS assay developed in yeast and its application to the study of origin function in other eukaryotes. Other available methods for detecting autonomous replication in these systems are also presented.
Analysis and design of an inverted-F antenna printed on a PCMCIA card for the 2.4 GHz ISM band (2002)

The development of small integrated antennas plays a significant role in the progress of rapidly expanding commercial communication applications. This paper addresses the analysis and design of an inverted-F antenna (IFA) printed on a PCMCIA card. The antenna is compact, easy to manufacture, and efficient, with an omni-directional pattern and a bandwidth of 250 MHz. The performance of the integrated IFA/PCMCIA system was simulated using two commercial method of moments codes, and validated with measurements on a fabricated prototype.
Five‐year follow‐up on the PAT study: specific immunotherapy and long‐term prevention of asthma in children (2006)

Immunotherapy for 3 years with standardized allergen extracts of grass and/or birch shows long-term clinical effect and preventive effect on development of asthma in children with seasonal rhinoconjunctivitis.
Deep Self-Taught Hashing for Image Retrieval (2018)

Hashing algorithm has been widely used to speed up image retrieval due to its compact binary code and fast distance calculation. The combination with deep learning boosts the performance of hashing by learning accurate representations and complicated hashing functions. So far, the most striking success in deep hashing have mostly involved discriminative models, which require labels. To apply deep hashing on datasets without labels, we propose a deep self-taught hashing algorithm (DSTH), which generates a set of pseudo labels by analyzing the data itself, and then learns the hash functions for novel data using discriminative deep models. Furthermore, we generalize DSTH to support both supervised and unsupervised cases by adaptively incorporating label information. We use two different deep learning framework to train the hash functions to deal with out-of-sample problem and reduce the time complexity without loss of accuracy. We have conducted extensive experiments to investigate different settings of DSTH, and compared it with state-of-the-art counterparts in six publicly available datasets. The experimental results show that DSTH outperforms the others in all datasets.
Einführung (1964)

Im täglichen Leben und in der Technik begegnet man zahlreichen, meist weichen Stoffen, welche sich durch verhältnismäßig geringen Kraftaufwand verformen lassen und welche ihre bei der Verformung erworbene äußere Gestalt beibehalten. Solche plastischen Stoffe sind z. B. Kuchenteig, Mörtel, Ton und Lehm, Dichtungsmassen und stichfeste Kalkbreie. Jeder, der Gelegenheit hatte, mit mehreren plastischen Stoffen umzugehen, macht die Erfahrung, daß die Plastizität bei den einzelnen Stoffen nicht nur in ihrem Ausmaß, sondern auch in ihrer »Art« irgendwie verschieden ist. Diese Verschiedenheit drückt sich auch in den unterschiedlichen Begriffsbestimmungen und Prüfverfahren für die Plastizität aus, die in den Gewerbezweigen und Industrien, welche sich mit plastischen Stoffen beschäftigen, aufgestellt oder vorgeschlagen werden.
[Progress of research on the expression and function of vimentin]. (2009)

As a kind of cytoskeleton protein, vimentin is a major member of intermediate filament family. Vimentin is found mainly in mesenchymal cells, and its expression and phosphorylation are regulated by many factors. In the past, vimentin was revealed as a scaffold maintaining cellular integrity, and recent studies shed lights on the evidence that vimentin played many important roles in cellular adhesion, growth, apoptosis, cell signaling as well as inflammatory response. This article summarizes the recent progress of vimentin about its expression and function.
채널 내를 비행하는 가변스팬 날개 공력특성 I (2016)

본 논문에서 채널 안내로를 비행하는 가변스팬 날개의 공력특성에 관한 실험연구를 수행하였다.
NACA 0012익형을 가진 가변스팬 날개를 제작하였으며 선형서보모터를 사용하여 작동시켰다. 날개의 가로세로비, 지면효과, 날개와 펜스사이의 거리가 날개의 공력특성에 미치는 영향을 조사하였다. 연구결과 지면 및 펜스 모두 항공기 날개의 양력을 증가시켰으며 지면효과와...
Learning to Anonymize Faces for Privacy Preserving Action Detection (2018)

There is an increasing concern in computer vision devices invading users' privacy by recording unwanted videos. On the one hand, we want the camera systems to recognize important events and assist human daily lives by understanding its videos, but on the other hand we want to ensure that they do not intrude people's privacy. In this paper, we propose a new principled approach for learning a video \emph{face anonymizer}. We use an adversarial training setting in which two competing systems fight: (1) a video anonymizer that modifies the original video to remove privacy-sensitive information while still trying to maximize spatial action detection performance, and (2) a discriminator that tries to extract privacy-sensitive information from the anonymized videos. The end result is a video anonymizer that performs pixel-level modifications to anonymize each person's face, with minimal effect on action detection performance. We experimentally confirm the benefits of our approach compared to conventional hand-crafted anonymization methods including masking, blurring, and noise adding. Code, demo, and more results can be found on our project page https://jason718.github.io/project/privacy/main.html.