gebhart/patrepeval huggingface dataset:
Hypothesis management for information fusion (2003)

The efficient management of large collections of fusion hypotheses presents a critical challenge for scaling high-level information fusion systems to solve large problems. We motivate this challenge in the context of two Alphatech research projects, and discuss several partial solutions. A recurring theme is the exploitation of space-efficient, factored representations of multiple hypotheses to enable an efficient search for good hypotheses.
A comparison of intranasal corticosteroid, leukotriene receptor antagonist, and topical antihistamine in reducing symptoms of perennial allergic rhinitis as assessed through the Rhinitis Severity Score (2010)

Rhinitis symptom complex consists of rhinorrhea, congestion, itchy mucosa, itchy eyes, and sneezing. Available medications vary in their benefit for each of these symptoms. It was the purpose of this article to compare symptom reduction with three different classes of medications. Montelukast, azelastine, and budesonide were compared to determine the effect on individual, as well as total, symptom scores using the Rhinitis Severity Score (RSS). All three medications were compared with placebo and showed efficacy in prior studies using Balaam's crossover design. The inclusion and exclusion criteria and all procedures were identical for all three studies. In analyzing the data from the RSS questionnaire, we used the procedure PROC MIXED in SAS specific for Balaam's crossover design (SAS Institute, Inc., Cary, NC). Although all three medications were effective compared with placebo, montelukast had the greatest effect of the three medications on reduction of ocular itching and throat and palate itching. Azelastine's effect was greater than budesonide and montelukast for reduction of rhinorrhea. Systemic medication, montelukast, as expected, provided better relief for symptoms distant from the nasal cavity, and the antihistamine, azelastine, reduced rhinorrhea, more than either montelukast or budesonide.
Self-Reactivities to the Non-Erythroid Alpha Spectrin Correlate with Cerebral Malaria in Gabonese Children (2007)

The repertoire of brain antigens recognized by plasma IgGs was more diverse in infected than in UI individuals. Anti-brain reactivity was significantly higher in the CM group than in the UM and SNCM groups. IgG self-reactivity to brain antigens was also correlated with plasma IgG levels and age. We found that 90% of CM patients displayed reactivity to a high-molecular mass band containing the spectrin non-erythroid alpha chain. Reactivity with this band was correlated with high TNFalpha concentrations in CM patients. These results strongly suggest that an antibody response to brain antigens induced by P. falciparum infection may be associated with pathogenic mechanisms in patients developing CM.
Fundamentals of Glacier Dynamics (2001)

Glaciers form when snow melts and refreezes, or is compressed, to form ice. Spreading under their own weight, they flow seaward, channeled along preferred routes by the shape or composition of the underlying bedrock. Though we don't know why, some ice streams flow rapidly within slower‐moving ice in Greenland and Antarctica. Glaciers exist on all continents except Australia, and at high enough elevations, they can be found even at the equator. Many are melting as global temperatures rise, but about 99% of glacier ice is in Greenland and Antarctica, where it is partly protected from global warming by low temperatures. Nevertheless, the coastal ice sheet in Greenland has thinned recently for unknown reasons, and we still don't know whether the far larger Antarctic ice sheet is growing or shrinking.
Procalcitonin in paediatric cancer patients: its diagnostic relevance is superior to that of C-reactive protein, interleukin 6, interleukin 8, soluble interleukin 2 receptor and soluble tumour necrosis factor receptor II (2000)

Sensitive parameters of inflammation are rare in neutropenic cancer patients. In this study, procalcitonin (PCT), C-reactive protein (CRP), interleukin 6 (IL-6), IL-8, the soluble IL-2 receptor (sIL-2R) and the soluble tumour necrosis factor receptor II (sTNFRII) were evaluated for their diagnostic relevance in febrile episodes of cancer patients. Plasma or serum levels of these parameters were determined in neutropenic children with febrile episodes (n = 122) classified according to both the kind of infection [60 cases of fever of unknown origin (FUO), 28 cases of localized infection, 13 cases of pneumonia, 20 cases of bacteraemia, one case of fungaemia] and the World Health Organization (WHO) score of chemotherapy-induced mucositis. At baseline and during the febrile episodes, the highest levels of all parameters were observed in cases of gram-negative bacteraemia. However, in FUO and localized infections, low or only slightly elevated median levels of all parameters were documented. The degree of chemotherapy-induced mucositis did not influence the value of any parameter. In comparison with the other inflammatory parameters, PCT (optimum cut-off level 0.5 microg/l) was a more sensitive and more specific parameter in the diagnosis of high-risk (gram-negative bacteraemia) and low-risk (FUO) episodes, as well as in the sequential assessment of all febrile neutropenic episodes.
Tumor-localizing components of the porphyrin preparation hematoporphyrin derivative. (1983)

Synthetic and analytical approaches were used to characterize the tumor-localizing components of the porphyrin preparation, hematoporphyrin derivative. From studies involving aqueous and nonaqueous gel exclusion and reverse-phase chromatography, we conclude that localization is mediated by hematoporphyrin derivative components which are among the most hydrophobic in the preparation. This apparent hydrophobicity may derive from hydrogen-bonding phenomena, rather than from absence of hydrophilic functional groups.
Mobile Edge Intelligence and Computing for the Internet of Vehicles (2019)

The Internet of Vehicles (IoV) is an emerging paradigm that is driven by recent advancements in vehicular communications and networking. Meanwhile, the capability and intelligence of vehicles are being rapidly enhanced, and this will have the potential of supporting a plethora of new exciting applications that will integrate fully autonomous vehicles, the Internet of Things (IoT), and the environment. These trends will bring about an era of intelligent IoV, which will heavily depend on communications, computing, and data analytics technologies. To store and process the massive amount of data generated by intelligent IoV, onboard processing and cloud computing will not be sufficient due to resource/power constraints and communication overhead/latency, respectively. By deploying storage and computing resources at the wireless network edge, e.g., radio access points, the edge information system (EIS), including edge caching, edge computing, and edge AI, will play a key role in the future intelligent IoV. EIS will provide not only low-latency content delivery and computation services but also localized data acquisition, aggregation, and processing. This article surveys the latest development in EIS for intelligent IoV. Key design issues, methodologies, and hardware platforms are introduced. In particular, typical use cases for intelligent vehicles are illustrated, including edge-assisted perception, mapping, and localization. In addition, various open-research problems are identified.
Reverse engineering legacy Web applications with phpModeler (2011)

Web applications are complex systems that are in the core of many businesses. However, their development is, contrary to other domains, not characterized by rigorous software engineering methods. The consequence is that many web applications are poorly structured and are not adequately documented, which leads to difficult maintenance. One way for dealing with web application complexity is their modeling on a higher level of abstraction. This also provides the possibility to cope with continuous evolution of web applications. In this paper we present phpModeler, a tool for reverse engineering of legacy PHP web applications. It generates static UML diagrams showing resources that each web page is using, web page's functions and dependencies it has on other web pages. Once the models have been created, phpModeler can analyze them and generate dependency models for each entity in every web page model. phpModeler can also be used to highlight the difference between page models - a feature that, when combined with an SVN repository shows the way how a web page has evolved over time. Tool usability has been tested on a case study application - iForestFire.
A visual recipe book for persons with language impairments (2005)

Cooking is a daily activity for many people. However, traditional text recipes are often prohibitively difficult to follow for people with language disorders, such as aphasia. We have developed a multi-modal application that leverages the retained ability of aphasic individuals to recognize image-based representations of objects, providing a presentation format that can be more easily followed than a traditional text recipe. Through a systematic approach to developing a visual language for cooking, and the subsequent case study evaluation of a prototype developed according to this language, we show that a combination of visual instructions and navigational structure can help individuals with relatively large language deficits to cook more independently.
Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity. (1992)

Thrombomodulin is an endothelial cell thrombin receptor that serves as a cofactor for thrombin-catalyzed activation of protein C. Structural requirements for thrombin binding and cofactor activity were studied by mutagenesis of recombinant human thrombomodulin expressed on COS-7 and CV-1 cells. Deletion of the fourth epidermal growth factor (EGF)-like domain abolished cofactor activity but did not affect thrombin binding. Deletion of either the fifth or the sixth EGF-like domain markedly reduced both thrombin binding affinity and cofactor activity. Thrombin binding sequences were also localized by assaying the ability of synthetic peptides derived from thrombomodulin to compete with diisopropyl fluorophosphate-inactivated 125I-thrombin binding to thrombomodulin. The two most active peptides corresponded to (a) the entire third loop of the fifth EGF-like domain (Kp = 85 +/- 6 microM) and (b) parts of the second and third loops of the sixth EGF-like domain (Kp = 117 +/- 9 microM). These data suggest that thrombin interacts with two discrete elements in thrombomodulin. Deletion of the Ser/Thr-rich domain dramatically decreased both thrombin binding affinity and cofactor activity and also prevented the formation of a high molecular weight thrombomodulin species containing chondroitin sulfate. Substitutions of this domain with polypeptide segments of decreasing length and devoid of glycosylation sites progressively decreased both cofactor activity and thrombin binding affinity. This correlation suggests that increased proximity of the membrane surface to the thrombin binding site may hinder efficient thrombin binding and the subsequent activation of protein C. Membrane-bound thrombomodulin therefore requires the Ser/Thr-rich domain as an important spacer, in addition to EGF-like domains 4-6, for efficient protein C activation.
An Adjustable Quasi-Optical Bandpass Filter---Part I: Theory and Design Formulas (1974)

A quasi-optical bandpass filter suitable for millimeter and submilliieter wavelengths and in the far infrared region is described. It consists of three or more wire-grid polarizers with quarter-wave spacings. The filter has the advantage over conventional quasi-optical filters, e.g., Fabry-Perot filters, that its bandwidth and the shape of its frequency response are adjustable. This is achieved by changing the angular orientations of the wires of the different polarizers. The filter requires the input electric field to be linearly polarized in a direction perpendicular to the wires of the first grid. The theory of operation is presented and design formulas for the filter are given, under the assumption that ideal wire-grid polarizers are employed. The effects of using realistic grids on the performance of the filter are dealt within another paper.
Studies of the Mechanism of the Periodic Acid-Schiff Histochemical Reaction for Glycogen Using Infrared Spectroscopy and Model Chemical Compounds (1977)

It has been proposed in the literature that Schiffs reagent reacts with aldehydes to form one of the following types of compounds: alkylsulfonic acids, N-sulfinic acid derivatives, or Schiff bases. Model compounds whose structures are consistent with those proposed in the literature have been synthesized and subjected to infrared analysis. Also, actual products of Schiff reagent reactions with various aldehydes have been isolated and examined using infrared spectroscopy. Comparison of the spectra of the model compounds with those of Schiff-aldehyde reaction products yielded the following conclusions: 1. The reaction of simple organic aldehydes with Schiff's reagent produces an alkylsulfonate-type reaction product. 2. The reaction of periodate-oxidized glycogen with Schiff's reagent probably involves the formation of an alklsulfonate-type compound. 3. The product of the Schiff-aldehyde reaction exists as neither an N-sulfinic acid nor a Schiff base derivative of the fuchsin molecule.
Fluorescent microplate assay for respiratory burst of PMNs challengedin vitro with orthopedic metals (1998)

This report describes a simple, rapid, automated microassay for measuring in vitro changes of oxidative burst of phagocytes following challenge with metals for orthopedic devices. The production of reactive oxygen species (ROS) by polymorphonuclear leukocytes (PMNs) was measured using 2',7'-dichlorofluorescin-diacetate (DCFH-DA) as fluorescent probe. DCFH-DA enters the cells and is oxidized by ROS to fluorescent DCF. The DCF generated was directly proportional to ROS produced intracellularly: The fluorescence intensity was read and converted to an index of ROS production by cells. In our experimental system, granulocytes (PMNs) were isolated from normal human blood and seeded in microplates. To verify if metals could influence ROS production, chromium, cobalt, nickel, molybdenum, titanium, aluminum, and vanadium prepared as aqueous extracts in phosphate-buffered saline were tested onto PMNs using phorbolmyristate acetate (PMA) as positive control. Molybdenum, aluminum, and vanadium increased ROS generation by PMNs, while signals not different from unstimulated PMNs were recorded for chromium, cobalt, nickel, and titanium. The DCFH-DA microplate-based assay provides an in vitro tool for the detection of oxygen-reactive species generated by PMNs as a response to metals.
Different types of hypersensitive sites in the mouse metallothionein gene region. (1987)

We have examined the chromatin structure of the metallothionein (MT) gene region in MT- S49 mouse lymphoma cells and in derivatives which express MT-I alone, MT-II alone, or both genes. In all lines, these genes are contained in a 16-kilobase pair region between two DNase I sensitive sites: one site located 5.3 kilobase pairs 5' of MT-II (the 5' gene) is present in naked DNA and retained in the chromatin of all lines; the other site located 3.1 kilobase pairs 3' of MT-I is hypersensitive. Hypersensitivity at three other sites is dependent on the expression of MT genes. Two sites 5' of MT-II disappear, and a site 3' of MT-I appears regardless of which gene is activated. The fact that these sites respond when either gene is activated suggests that the regulation of the two genes is interdependent and that the region undergoes a general change in conformation with MT activation. In addition, a single site in the 5' region of MT-II becomes hypersensitive with activation of the gene and may be related directly to expression.
Multi-pole magnetization of high resolution magnetic encoder (2002)

The construction of the magnetic encoder with a magnetoresistance sensor and a multi-pole magnetic drum is described. A rotatory magnetization system has been developed to magnetize the magnetic encoder. It is found that the sine-PWM magnetization is superior over the single-pulse magnetization when high resolution is needed.
5.8 GHz phased array antenna for electronic toll collection in road traffic applications (2002)

Concept and realization of a phased array antenna for road traffic applications based on the 5.8 GHz dedicated short range communication standard is presented. Localization and tracking of vehicles is possible even at high velocities and under critical signal situations. Measurements confirm a robust system performance and high reliability.
WO<sub>3–x</sub>@Au@MnO<sub>2</sub> Core–Shell Nanowires on Carbon Fabric for High‐Performance Flexible Supercapacitors (2012)

WO3–x@Au@MnO2 core–shell nanowires (NWs) are synthesized on a flexible carbon fabric and show outstanding electrochemical performance in supercapacitors such as high specific capacitance, good cyclic stability, high energy density, and high power density. These results suggest that the WO3–x@Au@MnO2 NWs have promising potential for use in high-performance flexible supercapacitors.
Bacteriophage Ecology in a Commercial Cucumber Fermentation (2012)

To reduce high-salt waste from cucumber fermentations, low-salt fermentations are under development. These fermentations may require the use of starter cultures to ensure normal fermentations. Because potential phage infection can cause starter culture failure, it is important to understand phage ecology in the fermentations. This study investigated the phage ecology in a commercial cucumber fermentation. Brine samples taken from a fermentation tank over a 90-day period were plated onto deMan-Rogosa-Sharpe agar plates. A total of 576 lactic acid bacterial isolates were randomly selected to serve as potential hosts for phage isolation. Filtered brine served as a phage source. Fifty-seven independent phage isolates were obtained, indicating that 10% of the bacterial isolates were sensitive to phage attack. Phage hosts include Lactobacillus brevis (67% of all hosts), Lactobacillus plantarum (21%), Weissella paramesenteroides, Weissella cibaria, and Pediococcus ethanolidurans. Nearly 50% of phages were isolated on day 14, and the majority of them attacked L. brevis. Some phages had a broad host range and were capable of infecting multiple hosts in two genera. Other phages were species specific or strain specific. About 30% of phage isolates produced turbid pinpoint plaques or only caused reduced cell growth on the bacterial lawns. Six phages with distinct host ranges were characterized. The data from this study showed that abundant and diverse phages were present in the commercial cucumber fermentation, which could cause significant mortality to the lactic acid bacteria population. Therefore, a phage control strategy may be needed in low-salt cucumber fermentations.
Motion planning for the Virtual Bronchoscopy (2012)

Bronchoscopy is an interventional medical procedure employed to analyze the interior side of the human airways, clear possible obstructions and biopsy. Using a 3D reconstruction of the tracheobronchial tree, Virtual Bronchoscopy (VB) may help physicians in the exploration of peripheral lung lesions. We are developing a haptic-based navigation system for the VB that allows the navigation within the airways using a haptic device whose permitted motions mimics those done with the real bronchoscope. This paper describes the motion planning module of the system devoted to plan a path from the trachea to small peripheral pulmonary lesions, that takes into account the geometry and the kinematic constraints of the bronchoscope. The motion planner output is used to visually and haptically guide the navigation during the virtual exploration using the haptic device. Moreover, physicians can get useful information of whether the peripheral lesions can effectively be reached with a given bronchoscope or of which is the nearest point to the lesion that can be reached.
Glycosylated minor components of human adult hemoglobin. Purification, identification, and partial structural analysis. (1978)

Human hemolysate contains several minor components designated Hb A1a, Hb A1b, Hb A1c, which are post-translational modifications of the major hemoglobin component A0. Individuals with diabetes mellitus have elevated levels of Hb A1c, a hemoglobin modified with a glucose moiety at the NH2 terminus of each beta chain. A new chromatographic technique using Bio-Rex 70 is described which not only allows complete separation of Hb A1a from Hb A1b but also resolution of Hb A1a into two components, designated Hb A1a1 and Hb A1a2. Carbohydrate determinations with the thiobarbituric acid procedure revealed that Hb A1a1, Hb A1a2, and Hb A1b as well as Hb A1c were glycosylated. Total phosphate analysis revealed 2.06 and 1.01 mol of phosphorus/alphabeta dimer for Hb A1a1 and Hb A1a2 respectively; Hb A1b and Hb A1c contained no detectable phosphate. Hemoglobin incubated with D-[14C]glucose-6-P co-chromatographs precisely with Hb A1a2, strongly suggesting that Hb A1a2 is glucose-6-P hemoglobin. Levels of Hb A1a1 and Hb A1a2 are normal in individuals with diabetes mellitus. Furthermore, diabetic red cells contain normal levels of glucose-6-P. Therefore, glucose-6-P hemoglobin does not serve as a significant precursor to Hb A1c. Instead Hb A1c is formed by the direct reaction of hemoglobin with glucose. This suggests that hemoglobin can serve as a model system for nonenzymatic glycosylation of protein.
Syntheses and reactions of silyl carbamates. 2. A new mode of cyclic carbamate formation from tert-butyldimethylsilyl carbamate (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSyntheses and reactions of silyl carbamates. 2. A new mode of cyclic carbamate formation from tert-butyldimethylsilyl carbamateMasahiro Sakaitani and Yasufumi OhfuneCite this: J. Am. Chem. Soc. 1990, 112, 3, 1150–1158Publication Date (Print):January 1, 1990Publication History Published online1 May 2002Published inissue 1 January 1990https://pubs.acs.org/doi/10.1021/ja00159a040https://doi.org/10.1021/ja00159a040research-articleACS PublicationsRequest reuse permissionsArticle Views1497Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts