gebhart/patrepeval huggingface dataset:
A new method for the prediction of liquid pulsed sieve‐tray extractors (1987)

Abstract As a part of a research project on the mass transfer in liquid pulsed sieve‐tray extraction columns (PSE), the diameters and hold‐ups of the drops were measured: the drop size using a suction technique, with photoelectric detection, which was adapted to the special boundary conditions of the PSE; the integral hold‐up by the pressure difference between the lower and upper parts of the column. Since experimental results cannot be described by known calculation formulae for the Sauter mean diameter and the hold‐up, a new method of calculation was developed. It is phenomenologically based on high‐speed photographs of the drop motion on a sieve tray. The mathematical‐physical model allows the prediction of drop size and hold‐up within certain limits, while the possible different operating regimes of the PSE, i.e. the mixer‐settler and dispersion regimes can also be estimated.
Immunoassay of serum conjugates of cholic acid in cystic fibrosis. (1980)

Pre- and post-prandial serum conjugates of cholic acid (SCCA) were measured by radioimmunoassay (RIA) in 83 patients with cystic fibrosis (CF), 14 of whom did not have steatorrhoea, and in 25 controls. Of the CF patients with steatorrhoea, 38% had fasting SCCA levels greater than 3 standard deviations above mean fasting control values, whereas no CF patient without steatorrhoea had elevated fasting SCCA levels. Steatorrhoeic patients with palpable livers had higher pre- and post-prandial SCCA levels. Post-prandial SCCA levels failed to discriminate between control and CF groups however. Other serum tests of liver function, including the aspartate amino transferase, alkaline phosphatase, albumin, gamma globulin, and albumin : globulin ratio, failed to correlate with the SCCA. Changes in serum protein constituents correlated strongly with pulmonary dysfunction. The results suggest that elevation of fasting SCCA levels in CF patients is a more sensitive indicator of liver dysfunction than other tests and is a better discriminator than post-prandial SCCA levels between normal and abnormal liver function. The test is recommended for early detection of liver dysfunction in CF patients.
Quartz-Based GaAs Schottky Diodes-Lifetime and Failure Analysis (1998)

A previously reported technology that allows for the fabrication of semiconductor devices based on quartz (or other dissimilar substrates) has resulted in state-of-the-art mixer performance at frequencies up to 640 GHz. The present work will discuss the procedure that has been used to quantify the reliability of such devices for space-borne missions. A number of accelerated lifetime tests have been conducted. It is concluded that these devices exhibit lifetimes that are consistent with other GaAs devices for space applications. Our accelerated lifetime data, analyzed with the Arrhenius-lognormal model, predict a room temperature MTTF on the order of 1010 hours, a value that is comparable to conventional high-frequency planar Schottky diodes. This result demonstrates that the use of an appropriate epoxy to obtain GaAs devices on quartz substrates does not reduce the lifetime of the devices. I.
Arabidopsis IQD1, a novel calmodulin‐binding nuclear protein, stimulates glucosinolate accumulation and plant defense (2005)

Glucosinolates are a class of secondary metabolites with important roles in plant defense and human nutrition. To uncover regulatory mechanisms of glucosinolate production, we screened Arabidopsis thaliana T-DNA activation-tagged lines and identified a high-glucosinolate mutant caused by overexpression of IQD1 (At3g09710). A series of gain- and loss-of-function IQD1 alleles in different accessions correlates with increased and decreased glucosinolate levels, respectively. IQD1 encodes a novel protein that contains putative nuclear localization signals and several motifs known to mediate calmodulin binding, which are arranged in a plant-specific segment of 67 amino acids, called the IQ67 domain. We demonstrate that an IQD1-GFP fusion protein is targeted to the cell nucleus and that recombinant IQD1 binds to calmodulin in a Ca(2+)-dependent fashion. Analysis of steady-state messenger RNA levels of glucosinolate pathway genes indicates that IQD1 affects expression of multiple genes with roles in glucosinolate metabolism. Histochemical analysis of tissue-specific IQD1::GUS expression reveals IQD1 promoter activity mainly in vascular tissues of all organs, consistent with the expression patterns of several glucosinolate-related genes. Interestingly, overexpression of IQD1 reduces insect herbivory, which we demonstrated in dual-choice assays with the generalist phloem-feeding green peach aphid (Myzus persicae), and in weight-gain assays with the cabbage looper (Trichoplusia ni), a generalist-chewing lepidopteran. As IQD1 is induced by mechanical stimuli, we propose IQD1 to be novel nuclear factor that integrates intracellular Ca(2+) signals to fine-tune glucosinolate accumulation in response to biotic challenge.
<title>Time frequency signatures of micro-Doppler phenomenon for feature extraction</title> (2000)

In this paper, we introduce the concept of micro-Doppler phenomenon. Micro-Doppler induced by mechanical vibrating or rotating of structures in a target is potentially useful for detection, classification and recognition of targets. While the Doppler frequency due to target body is constant, the micro-Doppler due to vibration or rotating structures of a target is a function of the dwell time. This time-varying Doppler signature in the time-frequency domain may provide further information for target detection, classification and recognition.
Unrecognized Myocardial Infarction: Epidemiology, Clinical Characteristics, and the Prognostic Role of Angina Pectoris: The Reykjavik Study (1995)

At least one third of all myocardial infarctions were unrecognized. Prognosis and risk factor profiles for patients with recognized and unrecognized myocardial infarction were similar. Although those with unrecognized myocardial infarction were less likely than those with recognized myocardial infarction to have a history of angina pectoris, angina in these cases was usually associated with ischemic electrocardiographic changes and a poor prognosis, suggesting severe coronary heart disease.
Precipitating antibody against protease of Corynebacterium pyogenes in pigs. (1977)

Antibody in sera from pigs carrying an abscess associated with Corynebacterium pyogenes and healthy pigs was examined by the agar gel diffusion test. In the test, the concentrated culture fluid containing the protease of C. pyogenes was used as antigen. As a result, precipitating antibody was demonstrated in sera from 25 of 30 abscessed pigs and a few of the healthy pigs. When the relationship between precipitating antibody and protease was examined by the immunoelectrophoresis and gel filtration of the concentrated culture fluid, the antibody was shown in the same position as the protease. From the result, it was clear that the precipitating antibody was against the protease of C. pyogenes. All the proteases produced by 27 strains of C. pyogenes of porcine and bovine origin were serologically identical with one another. They were, however, serologically different from those of Staphylococcus aureus, Bacillus cereus, and B. subtilis. In the inhibition test, the proteolytic activity of C. pyogenes was inhibited by the serum of the abscessed pig. It was also inhibited by healthy pig serum. From the results, it seems that the determination of precipitating antibody may be useful for the diagnosis of C. pyogenes infection.
Intermittent Administration of Parathyroid Hormone 1–34 Enhances Osteogenesis of Human Mesenchymal Stem Cells by Regulating Protein Kinase Cδ (2017)

Human mesenchymal stem cells (hMSCs) can differentiate into osteoblasts and are regulated by chemical cues. The recombinant N-terminal (1-34 amino acids) fragment of the parathyroid hormone (PTH (1-34)) is identified to promote osteogenesis. The osteoanabolic effects of intermittent PTH (1-34) treatment are linked to a complex consisting of signaling pathways; additionally, protein kinase C (PKC) act as mediators of multifunctional signaling transduction pathways, but the role of PKC δ (PKCδ), a downstream target in regulating osteoblast differentiation during intermittent administration of PTH (1-34) is less studied and still remains elusive. The purpose of this study is to examine the role of PKCδ during intermittent and continuous PTH (1-34) administration using osteoblast-lineage-committed hMSCs. Relative gene expression of osteoblast-specific genes demonstrated significant upregulation of <i>RUNX2</i>, <i>type I Collagen</i>, <i>ALP</i>, and <i>Osterix</i> and increased alkaline phosphatase activity in the presence of PTH (1-34). Intermittent PTH (1-34) administration increased PKC activity at day 7 of osteogenic differentiation, whereas inhibition of PKC activity attenuated these effects. In addition, the specific isoform PKCδ was activated upon treatment. These findings demonstrate that intermittent PTH (1-34) treatment enhances the osteogenesis of hMSCs by upregulating osteoblast-specific genes via PKCδ activation.
FPGA implementation of rate-adaptive spatially coupled LDPC codes suitable for optical communications (2019)

In this paper, we propose a unified field-programmable gate array (FPGA) structure for a rate-adaptive forward error correction (FEC) scheme based on spatially coupled (SC) LDPC codes derived from quasi-cyclic (QC) LDPC codes. We described the unified decoder structure in detail and showed that the rate adaptation can be achieved by a controller on-the-fly. By FPGA based emulation, the results show that, with comparable complexity, the SC codes provide larger coding gain. The implemented unified structure can be employed for any template QC-LDPC code to achieve a spatially-coupling based code-rate adaptation scheme.
The multifaceted roles of <scp>RNA</scp> binding in <scp>APOBEC</scp> cytidine deaminase functions (2014)

Cytidine deaminases have important roles in the regulation of nucleoside/deoxynucleoside pools for DNA and RNA synthesis. The APOBEC family of cytidine deaminases (named after the first member of the family that was described, Apolipoprotein B mRNA Editing Catalytic Subunit 1, also known as APOBEC1 or A1) is a fascinating group of mutagenic proteins that use RNA and single-stranded DNA (ssDNA) as substrates for their cytidine or deoxycytidine deaminase activities. APOBEC proteins and base-modification nucleic acid editing have been the subject of numerous publications, reviews, and speculation. These proteins play diverse roles in host cell defense, protecting cells from invading genetic material, enabling the acquired immune response to antigens and changing protein expression at the level of the genetic code in mRNA or DNA. The amazing power these proteins have for interphase cell functions relies on structural and biochemical properties that are beginning to be understood. At the same time, the substrate selectivity of each member in the family and their regulation remains to be elucidated. This review of the APOBEC family will focus on an open question in regulation, namely what role the interactions of these proteins with RNA have in editing substrate recognition or allosteric regulation of DNA mutagenic and host-defense activities.
Self-Healing of Polymers via Synchronous Covalent Bond Fission/Radical Recombination (2011)

The present paper is devoted to preparation of intrinsic self-healing polymeric materials used for structural applications. The authors introduced a novel healing chemistry based on dynamically reversible C–ON bonds, which imitates natural healing in living bodies without affecting their operations. To verify its feasibility, alkoxyamine moieties served as intermolecular links in polystyrene. Upon heating, covalent bond fission and radical recombination synchronously took place among alkoxyamine moieties. Cracked parts were thus reconnected repeatedly, without losing integrity and load bearing ability of the material even above Tg.
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR (2006)

Recently discovered, angiotensin-converting enzyme-2 (ACE2) is an important therapeutic target in the control of cardiovascular diseases as a result of its proposed central role in the control of angiotensin peptides. Thus our objective in the present study was to determine whether ACE2 gene transfer could decrease high blood pressure (BP) and would improve cardiac dysfunctions induced by hypertension in the spontaneously hypertensive rat (SHR) model. Five-day-old SHR and normotensive WKY rats received a single intracardiac bolus injection of lentiviral vector containing either murine ACE2 (ACE2) or control enhanced green fluorescent protein (EGFP) genes. Systolic BP, cardiac functions, and perivascular fibrosis were evaluated 4 mo after ACE2 gene transduction. ACE2 gene transfer resulted in a significant attenuation of high BP in the SHR (149 ± 2 mmHg in lenti-ACE2 vs. 180 ± 9 mmHg in lenti-EGFP, P < 0.01). In contrast, no significant effect of lenti-ACE2 on BP of WKY rats was observed. Lenti-ACE2-treated SHR showed an 18% reduction in left ventricular wall thickness (1.52 ± 0.04 vs. 1.86 ± 0.04 mm in lenti-EGFP, P < 0.01). In addition, there was a 12% increase in left ventricular end diastolic and a 21% increase in end systolic diameters in lenti-ACE2-treated SHR. Finally, lenti-ACE2 treatment resulted in a significant attenuation of perivascular fibrosis in the SHR. In contrast, ACE2 gene transfer did not influence any of these parameters in WKY rats. These observations demonstrate that ACE2 overexpression exerts protective effects on high BP and cardiac pathophysiology induced by hypertension in the SHR.
Sur la croissance des fonctions entières (1930)

1. Notations et remarques prliminaires. -Mettant en vidence les modules et les arguments des coefficients, nous dsignerons la fonction entire tudie par
From the Editor (1997)

Health Care Management Review (HCMR) disseminates state-of-the-art knowledge about management, leadership, and administration of health care systems, organizations, and agencies. Multidisciplinary and international in scope, articles present completed research relevant to health care management, leadership, and administration, as well report on rigorous evaluations of health care management innovations, or provide a synthesis of prior research that results in evidence-based health care management practice recommendations. Articles are theory-driven and translate findings into implications and recommendations for health care administrators, researchers, and faculty. Annually, HCMR publishes the Best Theory to Practice paper chosen by the Health Care Administration Division of the Academy of Management.
Pagemap: A dynamic user guiding approach to the most relevant and popular pages in a website (2010)

In this blooming age of information technology the web developers always intend to provide a vast information space to the Internet surfers. On the other side, the users always want to reach the desired information by least effort. As a result, the increasing volume of information in each website also enlarges the searching domain for the user. In many cases, the user fails to spot his desired information at a quick outlook and then frequently switches to other similar websites. Some approaches like Sitemap, Footprints etc. give an overview of the site contents but often fail to guide the user to his destined information. This paper proposes a new approach named Pagemap, which can guide a user to the most popular and relevant pages of that website based on user's current location within that domain. With the assistance of the access log file, Pagemap uses the previous browsing history to find the most popular pages in a website. Pagemap uses the vector space model to find out the pages with maximum matching in compare to the current page of the user. Usability analysis method is used to justify the efficiency of Pagemap which shows it's the usefulness of this approach.
A low-IF/zero-IF reconfigurable receiver with two-step channel selection technique for multistandard applications (2004)

This paper presents a low-IF/zero-IF reconfigurable receiver for multistandard applications based on a two-step channel selection (2-SCS) technique. Such technique is mainly implemented by a reconfigurable sampling scheme, which can perform either programmable Analog-Double Quadrature Sampling (A-DQS) or Analog-Baseband Sampling (A-BS) to, first, relax the front-end PLL-frequency synthesizer (PLL-FS) locking time and phase noise requirements; and, second, allow a low-IF architecture to be transformable to zero-IF with small overheads. In this way, the receiver can operate in low-IF mode for narrowband standards avoiding 1/f noise and DC offset, and alternatively, for wideband standards, it can be reconfigured seamlessly in zero-IF mode to minimize image interference. The operating principles, design considerations and circuit implementation of such schemes for multistandard applications, including Bluetooth, HomeRF and IEEE 802.11FH, demonstrate the flexibility of such topology.
Real-Time Pedestrian Detection with Deep Network Cascades (2015)

We present a new real-time approach to object detection that exploits the efficiency of cascade classifiers with the accuracy of deep neural networks. Deep networks have been shown to excel at classification tasks, and their ability to operate on raw pixel input without the need to design special features is very appealing. However, deep nets are notoriously slow at inference time. In this paper, we propose an approach that cascades deep nets and fast features, that is both very fast and very accurate. We apply it to the challenging task of pedestrian detection. Our algorithm runs in real-time at 15 frames per second. The resulting approach achieves a 26.2% average miss rate on the Caltech Pedestrian detection benchmark, which is competitive with the very best reported results. It is the first work we are aware of that achieves very high accuracy while running in real-time.
Microscale Silicon Origami (2016)

A new methodology to create 3D origami patterns out of Si nanomembranes using pre-stretched and pre-patterned polydimethylsiloxane substrates is reported. It is shown this approach is able to mimic paper-based origami patterns. The combination of origami-based microscale 3D architectures and stretchable devices will lead to a breakthrough on reconfigurable systems.
The <i>Arabidopsis</i> aldehyde oxidase 3 ( <i>AAO3</i> ) gene product catalyzes the final step in abscisic acid biosynthesis in leaves (2000)

Abscisic acid (ABA) is a plant hormone involved in seed development and germination and in responses to various environmental stresses. The last step of ABA biosynthesis involves oxidation of abscisic aldehyde, and aldehyde oxidase (EC ) is thought to catalyze this reaction. An aldehyde oxidase isoform, AOdelta, encoded by AAO3, one of four Arabidopsis aldehyde oxidase genes (AAO1, AAO2, AAO3, and AAO4), is the most likely candidate for the enzyme, because it can efficiently catalyze the oxidation of abscisic aldehyde to ABA. Here, we report the isolation and characterization of an ABA-deficient Arabidopsis mutant that maps at the AAO3 locus. The mutant exhibits a wilty phenotype in rosette leaves, but seed dormancy is not affected. ABA levels were significantly reduced in the mutant leaves, explaining the wilty phenotype in rosettes, whereas the level in the mutant seeds was less reduced. No AOdelta activity could be detected in the rosette leaves of the mutant. Sequence data showed that the mutant contains a G to A substitution in the AAO3 gene. The mutation causes incorrect splicing of the ninth intron of AAO3 mRNA. We thus conclude that the ABA-deficient mutant is impaired in the AAO3 gene and that the gene product, AOdelta, is an aldehyde oxidase that catalyzes the last step of ABA biosynthesis in Arabidopsis, specifically in rosette leaves. Other aldehyde oxidases may be involved in ABA biosynthesis in other organs.
A model of the exchange bias setting process in magnetic read sensors (2009)

A model of the acquisition of exchange bias during the high temperature annealing process used to set the bias direction in the antiferromagnet is described. The model is applied to the investigation of the process of setting the bias direction in the antiferromagnetic layer, which comprises a high-temperature anneal in a field sufficiently large to saturate the ferromagnetic layers. It is shown that there is an optimal setting temperature depending on the material parameters. The temperature dependence of the antiferromagnetic anisotropy is shown to be an important factor in achieving maximum exchange bias.
Automatic design scheme for optical-fiber Raman amplifiers backward-pumped with multiple laser diode pumps (2001)

A simulated annealing algorithm is adopted to give an automatic pump configuration in laser-diode backward-pumped-distributed fiber Raman amplifiers. The demonstration of the optimization process of wavelengths and powers in an optical-fiber Raman amplifier using four laser-diode pumps is presented. The resulting gain ripple is less than 2.6 dB in respect to the 30 dB average gain in the amplification bandwidth of more than 50 nm (64 signal channels). The algorithm can be practically applied to the desired signal channel number and gain profile.
Correction to &#x201C;Graph Minor Approach for Application Mapping on CGRAs&#x201D; (2013)

Following the publication of the article “Graph Minor Approach for Application Mapping on CGRAs” [1] in the proceedings of the International Conference on Field Programmable Technology (ICFPT) 2012, we received correspondence [2] pointing to some inaccuracies in the article. With this correction, we would like to clarify some points that could otherwise be misconstrued.
An integrated-circuit based wide range electrometer implemented with automatically ranged linear display (1992)

An electrometer using a complementary metal-oxide semiconductor bilateral switch for automatic range control has been built. This circuit provides linear analog output over six orders of magnitude for current measurement without the need for constant adjustment of offset at different ranges. The application of integrated circuits makes the whole system stable and can be readily constructed.
Tetrazole Photoclick Chemistry: Reinvestigating Its Suitability as a Bioorthogonal Reaction and Potential Applications (2015)

The bioorthogonality of tetrazole photoclick chemistry has been reassessed. Upon photolysis of a tetrazole, the highly reactive nitrile imine formed undergoes rapid nucleophilic reaction with a variety of nucleophiles present in a biological system, along with the expected cycloaddition with alkenes. The alternative use of the tetrazole photoclick reaction was thus explored: tetrazoles were incorporated into Bodipy and Acedan dyes, providing novel photo-crosslinkers with one- and two-photon fluorescence Turn-ON properties that may be developed into protein-detecting biosensors. Further introduction of these photo-activatable, fluorogenic moieties into staurosporine resulted in the corresponding probes capable of photoinduced, no-wash imaging of endogenous kinase activities in live mammalian cells.
Gate-Voltage Studies of Discrete Electronic States in Aluminum Nanoparticles (1997)

We have investigated the spectrum of discrete electronic states in single, nm-scale Al particles incorporated into new tunneling transistors, complete with a gate electrode. The addition of the gate has allowed (a) measurements of the electronic spectra for different numbers of electrons in the same particle, (b) greatly improved resolution and qualitatively new results for spectra within superconducting particles, and (c) detailed studies of the gate-voltage dependence of the resonance level widths, which have directly demonstrated the effects of nonequilibrium excitations.