gebhart/patrepeval huggingface dataset:
Single-System Research Designs in Social Work Practice: A Bibliography From 1965 to 1990 (1992)

A comprehensive bibliography of articles, books, and book chapters authored by professional social workers and related to the theory and application of single-subject research designs in social work practice is presented. Over 250 citations are listed, spanning the years 1965 through 1990. This bibliography may be useful for social work practitioners seeking further instruction in the use of such designs, for social work students, and for scholarly use by professional educators.
Tracking of Tubular Objects for Scientific Applications (1994)

In this paper, we present a system for detection, tracking and representation of tubular objects in images. The uniqueness of the proposed system is twofold: at the macro level, the novelty of the system lies in the integration of object localization and tracking using geometric properties; at the micro level, in the use of high and low level constraints to model the detection and tracking subsystem. The underlying philosophy for object detection is to extract perceptually significant features from the pixel level image, and then use these high level cues to refine the precise boundaries. In the case of tubular objects, the perceptually significant features are anti-parallel line segments or, equivalently, their axis of symmetries. The axis of symmetry infers a coarse description of the object in terms of a bounding polygon. The polygon then provides the necessary boundary condition for the refinement process, which is based on dynamic programming. For tracking the object in a time seq...
Modelling and analysis of a MEMS approach to dc voltage step-up conversion (2004)

This paper studies the principle of a novel voltage step-up converter based on a micromachined variable parallel-plate capacitor in combination with an electrostatic actuator. Electrical equivalent circuit and system-level SIMULINK models have been developed. Based on these models, an analysis of design parameters and expected device performance has been performed to serve as a starting point for a prototype implementation. Possible areas of application are self-powered, stand-alone sensing systems, aerospace applications and any kind of electrostatic or piezoelectric MEMS devices in general.
ELEMENTOS CONSTITUTIVOS E BREVES OBSERVAÇÕES SOBRE A ÉTICA KANTIANA (2020)

Esse escrito tem por objetivo expor e discutir os elementos constitutivos da ética kantiana como dever, imperativos, autonomia, dignidade e liberdade. O mesmo também tece algumas observações críticas sobre essa teoria. Immanuel Kant propõe uma moral formalista, fundamentada unicamente na razão. Nesta perspectiva há uma extrema valorização do racional em detrimento de qualquer determinação do sensível. Para Kant, a ação apenas será moral quando for ditada exclusivamente pela razão e não por algum interesse ou desejo pessoal, isto é, prático ou moral é o que depende unicamente da razão. A moralidade não se julga de fora. Por isso suas determinações não poderão vir da experiência. Os conteúdos morais vêm do interior, são imposições da razão e, como a razão é universal, isto é, está presente em todos os homens, é possível que todos possam agir de acordo com seus princípios.
Navigation made personal (2015)

All current navigation systems return efficient source-to-destination routes assuming a "one-size-fits-all" set of objectives, without addressing most personal preferences. Although they allow some customization (like "avoid highways" or "avoid tolls"), the choices are very limited and require some sophistication on the part of the user. In this paper we present, implement, and test a framework that generates personalized driving directions by automatically analyzing users' GPS traces. Our approach learns cost functions using coordinate descent, leveraging a state-of-the-art route planning engine for efficiency. In an extensive experimental study, we show that this framework infers user-specific driving preferences, significantly improving the route quality. Our approach can handle continental-sized inputs (with tens of millions of vertices and arcs) and is efficient enough to be run on an autonomous device (such as a car navigation system) preserving user privacy.
Serum levels of C1 subunits in rheumatoid arthritis. (1984)

Modifications of radial immunodiffusion and of hemolytic assays of C1q are described, which enable the results of these assays to be in agreement with those obtained by hydroxyproline assay. Using these assays, we show that C1q serum levels are significantly increased in rheumatoid arthritis (RA) and that the excess C1q levels in this disease are not accompanied by increased levels of C1r and C1s. Active RA is therefore characterized by increased levels of hemolytically active C1q that has a physiologically active stem region unbound to C1r and C1s.
Controlling Political Corruption in the United Kingdom (2006)

Existing case studies of control of political corruption often lack a theoretical framework that can provide for systematic empirical research and comparisons between cases and countries.\nTo remedy this, we apply principal-agent theory qualitatively to study the United Kingdom, with a particular emphasis given to an in-depth study of control measures employed to Parliament, the Executive and political parties. We give a detailed account of the approach undertaken to control political corruption in these risk areas for corruption, and discuss its\nimplications and why some types of measures prevail over others.
Treatment of chronic hepatitis B. (2010)

Approximately 350-420 million people worldwide are chronically infected with hepatitis B virus (HBV). Chronic hepatitis B can result in liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Reactivation of hepatitis B is possible in patients with inactive or resolved hepatitis B often leading to liver failure. Those sequelae may be prevented by effective antiviral therapy. Interferon alfa, pegylated interferon alfa and five direct antiviral nucleoside and nucleotide analogues are approved for the treatment of chronic hepatitis B. Still, whom to treat, which therapy regimen to use, and when to begin treatment remain the challenges in the management HBV-infected patients. This review focuses on the current treatment concepts for chronic hepatitis B.
Characterization and partial purification of a novel neutrophil membrane-associated kinase capable of phosphorylating the respiratory burst component p47phox (1999)

The phosphorylation of p47phox is widely viewed as an important step in the activation of the neutrophil respiratory burst oxidase system. The exact nature of the kinase(s) responsible remains to be elucidated. We show here that such a kinase was detected on neutrophil membranes activated by either PMA or formyl-methionyl-leucyl-phenylalanine. This enzyme is not intrinsic to the neutrophil membrane and could be eluted with 0.5 M NaCl. The kinase activity was partially purified and was found not to be due to the presence of previously suggested kinases, including protein kinase C isotypes, mitogen-activated protein kinase and protein kinase B. Gel filtration and renaturation in substrate gels suggest a molecular mass of between 45 and 51 kDa. The kinase activity was independent of calcium and lipids but was potently inhibited by staurosporine. Treatment with protein phosphatase 2Ac suggested that the kinase was activated by serine/threonine phosphorylation. Phosphopeptide maps indicated that the kinase phosphorylated p47phox on similar sites to those found in vivo. These results indicate that activation of neutrophils by PMA results in the activation of a membrane-associated kinase that may play a part in the regulation of neutrophil NADPH oxidase through its ability to phosphorylate p47phox.
Forster, Peter G. <i>The Esperanto Movement</i>. The Hague, Paris and New York: Mouton Publishers, 1982. (Contributions to the Sociology of Language, 32) (1983)

"Forster, Peter G. The Esperanto Movement. The Hague, Paris and New York: Mouton Publishers, 1982. (Contributions to the Sociology of Language, 32)." Canadian Modern Language Review, 40(1), pp. 141–142
Methods for transform, analysis and rendering of complete light representations (2007)

Recent advances in digital holography, optical engineering and computer graphics have opened up the possibility of full parallax, three dimensional displays. The premises of these rendering systems are however somewhat different from traditional imaging and video systems. Instead of rendering an image of the scene, the complete light distribution must be computed. In this thesis we discuss some different methods regarding processing and rendering of two well known full light representations: the light field and the hologram. A light field transform approach, based on matrix optics operators, is introduced. Thereafter we discuss the relationship between the light field and the hologram representations. The final part of the thesis is concerned with hologram and wave field synthesis. We present two different methods. First, a GPU accelerated approach to rendering point-based models is introduced. Thereafter, we develop a Fourier rendering approach capable of generating angular spectra of triangular mesh models.
Development progress in plasma source mass spectrometry (1983)

Development work in the application of the inductively coupled plasma to plasma source mass spectrometry is described. Preliminary results obtained under continuum (or bulk plasma) sampling conditions are illustrated and compared with previously published boundary layer sampling work. The technique is now shown to be viable for multi-element analysis of complex samples.
Automatic camera control using unobtrusive vision and audio tracking (2010)

Atrial fibrillation (AF) contributes significantly to morbidity and mortality in as many as one-third of patients after cardiac surgery that requires cardiopulmonary bypass (CPB). Recent data suggest that inflammatory infiltration of the myocardium may predispose to AF. We conducted an exploratory pilot study to determine if there was an association between the perioperative leukocyte inflammatory response to cardiac surgery/CPB and postoperative AF. We enrolled 72 patients undergoing cardiac surgery with CPB; all patients were in sinus rhythm before surgery. Leukocyte activation (CD11b upregulation) was perioperatively measured in monocytes and neutrophils (PMN). Preoperative C-reactive protein (CRP) and perioperative neutrophil myeloperoxidase (MPO) were also monitored for inflammation, and troponin I was assayed for perioperative cardiac muscle damage. All markers were evaluated for differences between the subset of patients who developed AF versus those who remained in normal sinus rhythm after surgery. All 72 patients completed the study. Postoperative AF developed in 26 (36%) patients. Perioperative monocyte CD11b upregulation was significantly increased in patients who developed AF (P = 0.01), but increases in PMN CD11b were not significantly associated with AF (P = 0.057). The increase in both monocyte and PMN counts after aortic cross-clamp release was significantly associated with postoperative AF (P = 0.007 and P = 0.005, respectively). By contrast, preoperative CRP and perioperative MPO did not differ between AF and normal rhythm patients. Similarly, the peak value of troponin I did not differ between groups. In this pilot study of cardiac surgery/CPB patients, perioperative upregulation of the monocyte adhesion receptor, CD11b, and higher circulating monocyte and PMN numbers were associated with postoperative AF, suggesting that the induction of cellular inflammation during cardiac surgery/CPB may contribute to this pathophysiology.
Frequency-domain wide-field laser Doppler in vivo imaging (2006)

We present a new instrument, based on a low-frame-rate (8 Hz) CCD camera used in a heterodyne optical-mixing configuration, that can create wide-field laser Doppler maps. As an illustration, we show results obtained in a mouse brain, in vivo, showing the Doppler signature of blood flow. The instrument is based on a frequency-shifting digital holography scheme.
Pro-Reactive Route Recovery with Automatic Route Shortening in Wireless Ad Hoc Networks (2011)

In this paper, we propose a relay recovery route maintenance protocol for ad hoc networks to combine the benefits of both proactive and reactive route recovery strategies and to minimize their drawbacks. In our proposal, one or more substitute routes usually become ready for the recovery of every link in a route before its break, while the route recovery process actually starts only when the upstream node of a link confirms the link break. Since this scheme does not broadcast any control packet, it can effectively recover a broken link without heavy control overhead traffic. Also, it helps reduce the time delay due to the recovery, since substitute routes are already available when the upstream node initiates the route recovery process. We further propose two automatic route shortening schemes to optimize the route during successful packet forwarding without causing extra control overhead. We have implemented our proposed schemes based on AODV and compared their performance with competitive schemes including original AODV. Simulation results demonstrate that our proposal definitely reduces the time delay and control overhead traffic in route repairing process, and that the route shortening schemes further leads to shorter time delay and average route length.
Notes: Alkylidene- and Arylideneaminomorpholines (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNotes: Alkylidene- and ArylideneaminomorpholinesRichard Wiley, H White, and Gether IrickCite this: J. Org. Chem. 1959, 24, 11, 1784–1786Publication Date (Print):November 1, 1959Publication History Published online21 July 2003Published inissue 1 November 1959https://pubs.acs.org/doi/10.1021/jo01093a602https://doi.org/10.1021/jo01093a602research-articleACS PublicationsRequest reuse permissionsArticle Views235Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Continuous Administration of Subcutaneous Levodopa/Carbidopa (ND0612) Demonstrated Comparable Levodopa Pharmacokinetics to Levodopa/Carbidopa Intestinal Gel (LCIG) (S4.003) (2017)

To compare the levodopa pharmacokinetics of ND0612, a proprietary liquid Levodopa/Carbidopa formulation, designed for subcutaneous administration with Levodopa/Carbidopa Intestinal Gel (LCIG).
Pyridinediimine Iron Complexes with Pendant Redox-Inactive Metals Located in the Secondary Coordination Sphere (2015)

A series of pyridinediimine (PDI) iron complexes that contain a pendant 15-crown-5 located in the secondary coordination sphere were synthesized and characterized. The complex Fe((15c5)PDI)(CO)2 (2) was shown in both the solid state and solution to encapsulate redox-inactive metal ions. Modest shifts in the reduction potential of the metal-ligand scaffold were observed upon encapsulation of either Na(+) or Li(+).
Phosphorylation of FANCD2 on Two Novel Sites Is Required for Mitomycin C Resistance (2006)

The Fanconi anemia (FA) pathway is a DNA damage-activated signaling pathway which regulates cellular resistance to DNA cross-linking agents. Cloned FA genes and proteins cooperate in this pathway, and monoubiquitination of FANCD2 is a critical downstream event. The cell cycle checkpoint kinase ATR is required for the efficient monoubiquitination of FANCD2, while another checkpoint kinase, ATM, directly phosphorylates FANCD2 and controls the ionizing radiation (IR)-inducible intra-S-phase checkpoint. In the present study, we identify two novel DNA damage-inducible phosphorylation sites on FANCD2, threonine 691 and serine 717. ATR phosphorylates FANCD2 on these two sites, thereby promoting FANCD2 monoubiquitination and enhancing cellular resistance to DNA cross-linking agents. Phosphorylation of the sites is required for establishment of the intra-S-phase checkpoint response. IR-inducible phosphorylation of threonine 691 and serine 717 is also dependent on ATM and is more strongly impaired when both ATM and ATR are knocked down. Threonine 691 is phosphorylated during normal S-phase progression in an ATM-dependent manner. These findings further support the functional connection of ATM/ATR kinases and FANCD2 in the DNA damage response and support a role for the FA pathway in the coordination of the S phase of the cell cycle.
Generative Image Inpainting with Contextual Attention (2018)

Recent deep learning based approaches have shown promising results for the challenging task of inpainting large missing regions in an image. These methods can generate visually plausible image structures and textures, but often create distorted structures or blurry textures inconsistent with surrounding areas. This is mainly due to ineffectiveness of convolutional neural networks in explicitly borrowing or copying information from distant spatial locations. On the other hand, traditional texture and patch synthesis approaches are particularly suitable when it needs to borrow textures from the surrounding regions. Motivated by these observations, we propose a new deep generative model-based approach which can not only synthesize novel image structures but also explicitly utilize surrounding image features as references during network training to make better predictions. The model is a feed-forward, fully convolutional neural network which can process images with multiple holes at arbitrary locations and with variable sizes during the test time. Experiments on multiple datasets including faces (CelebA, CelebA-HQ), textures (DTD) and natural images (ImageNet, Places2) demonstrate that our proposed approach generates higher-quality inpainting results than existing ones. Code, demo and models are available at: https://github.com/JiahuiYu/generative_inpainting.
Highly Efficient Multicolour Upconversion Emission in Transparent Colloids of Lanthanide‐Doped NaYF<sub>4</sub> Nanocrystals (2004)

Highly efficient photon upconversion in solution is demonstrated for the first time. Transparent colloidal solutions of Yb/Er and Yb/Tm doped NaYF4 nanocrystals show bright upconversion emission in the red, green, and blue spectral region by excitation around 1 μm with a laser of moderate power (see Figure). These new systems show a substantial improvement on the order of 108 compared to previously reported systems. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2004/c0772_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Reinforcement learning and the frame problem (2006)

The frame problem, originally proposed within AI, has grown to be a fundamental stumbling block for building intelligent agents and modeling the mind. The source of the frame problem stems from the nature of symbolic processing. Unfortunately, connectionist approaches have long been criticized as having weaker representational capabilities than symbolic systems so have not been considered by many. The equivalence between the representational power of symbolic systems and connectionist architectures is redressed through neural manifolds, and reveals an associated frame problem. Working within the construct of neural manifolds, the frame problem is solved through the use of contextual reinforcement learning, a new paradigm recently proposed.
L'assureur vie à la recherche des causes du décès de l'assuré (2011)

editorial reviewed
Nucleotide sequence of cloned cDNA specific for rat ribosomal protein L27 (1988)

We constructed cDNA libraries from 8-9-S poly(A)-rich RNA from regenerating rat liver, isolated clones specific for ribosomal protein L27 and determined the nucleotide sequences of the cDNA clones. The longest cDNA consists of 15 base pairs from the 5' leading sequence, the entire coding sequence of 411 base pairs, and the 3' trailing sequence of 59 base pairs including the poly(A) tail. The primary structure of protein L27 was deduced from the sequence of nucleotides. Protein L27 contains 135 amino acids and has a molecular mass of 15,666 Da. The amino-terminal sequence agreed well with the published partial amino acid sequence and the calculated amino acid composition is also consistent with the reported composition determined for the hydrolyzate of L27.
cDNA cloning and chromosomal localization of the human α‐adrenergic receptor kinase (1991)

The beta-adrenergic receptor kinase (beta ARK) mediates agonist-dependent phosphorylation of the beta 2-adrenergic and related G protein-coupled receptors. A cDNA encoding bovine beta ARK has recently been isolated. In this work we have isolated a cDNA encoding human beta ARK from a retinal cDNA library. The cDNA encodes a protein of 689 amino acids with an overall 98.0% amino acid and 92.5% nucleotide identity with bovine beta ARK. Chromosomal location of the human beta ARK gene was determined by correlating the presence of the beta ARK locus with retention of a specific human chromosome in a rodent-human hybrid panel. This analysis revealed that the human beta ARK locus segregated with the long arm of chromosome 11, centromeric to 11q13.
The Role of Vascular Mechanisms in the Development of Acute Equine Laminitis (1993)

Abstarct ACUTE LAMINITIS has long been attributed to factors or events that precede the onset of laminitis. Between 1759 and 1907 the overconsumption of grain, inflammation of the feet, suppression of perspiration (anhydrosis), excessive rest, excessive bleeding, road concussion, poor shoeing, unilateral weight bearing, sudden environmental temperature changes, prolonged standing (in the cold and aboard ships), diarrhea, and postpartum complications were all designated as causes. Today, commonly listed etiologic factors include ingestion of large amounts of grain, cold water, lush grass, or black walnut shavings, repeated concussion, endometritis or other severe infections, colic, exhaustion, stress, drug toxicities, and endocrine dysfunctions. At Texas A&M University (Table 1) the factors recorded as the cause presume a causal relationship between some preceding event and the acute laminitis. Logically, any event that precedes laminitis might be a cause, but etiologic validity depends on the definition of “cause” and the role that coincidence might have in the appearance of the disease.
Component for second-order compensation ofpolarisation-mode dispersion (1997)

The compensating polarisation-mode dispersion of long fibres using principal states of polarisation is limited in bandwidth when these states vary with frequency. A compensator, containing high birefringent fibres and polarisation controllers is described, which is adapted to these variations and promises an enlarged bandwidth.