gebhart/patrepeval huggingface dataset:
Electron capture negative ion chemical ionization mass spectrometry of derivatized chlorophenols and chloroanilines (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectron capture negative ion chemical ionization mass spectrometry of derivatized chlorophenols and chloroanilinesThomas M. Trainor and Paul. VourosCite this: Anal. Chem. 1987, 59, 4, 601–610Publication Date (Print):February 15, 1987Publication History Published online1 May 2002Published inissue 15 February 1987https://pubs.acs.org/doi/10.1021/ac00131a014https://doi.org/10.1021/ac00131a014research-articleACS PublicationsRequest reuse permissionsArticle Views175Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Discrete-Time Methods for the Analysis of Event Histories (1982)

The history of an individual or group can always be characterized as a sequence of events. People finish school, enter the labor force, marry, give birth, get promoted, change employers, retire, and ultimately die. Formal organizations merge, adopt innovations, and go bankrupt. Nations experience wars, revolutions, and peaceful changes of government. It is surely the business of sociology to explain and predict the occurrence of such events. Why is it, for example, that some individuals try marijuana while others do not? Why do some people marry early while others marry late? Do educational
Expression of bcl-2 in bladder neoplasms is a cell lineage associated and p53-independent event. (1997)

In bladder adenocarcinomas, bcl-2 expression correlated negatively with tumour grade whereas p53 was associated positively with tumour grade. The association of bcl-2 with cystitis glandularis and adenocarcinoma but not TCC suggests that it may be involved in triggering a lineage switch converting transitional epithelium to a glandular phenotype.
The D arm of tRNATyr is necessary and sufficient for import into Leishmania mitochondria in vitro (1998)

Transfer RNAs are selectively imported from the cytoplasm into mitochondria of kinetoplastid protozoa such as Leishmania . The specific structural features of tRNA which determine selectivity are largely unknown. Using an in organello system from Leishmania , the import signals on tRNATyrand on a synthetic transcript which binds to the same receptor, were studied by deletion and reconstruction analyses. In both cases, short oligoribonucleotides (minihelices) containing the sequence UGGYAGAG were imported with high efficiency in the presence of ATP. This motif is present in the D arm of tRNATyr, as well as in the majority of imported Leishmania tRNAs. Deletion of the D arm, or a point mutation in the conserved motif, reduces importability. The import signal coincides with the binding site for the mitochondrial receptor TAB. tRNAGln, which is not imported, forms non-productive, TAB-independent complexes with the mitochondrial surface. However, the observation that the imported:bound ratio of the D arm minihelix is higher than that of the entire molecule suggests that the post-binding translocation step is constrained in terms of size or structural flexibility. Kinetic studies of minihelix import indicate stepwise insertion of the molecule into import channels.
Agent-based Consumer Learning in E-Commerce. (2006)

In the age of information and knowledge, the role of business companies is not only just to sell products and services, but also to educate their consumers. Educating consumers with extremely diversified backgrounds about technical knowledge is an important part of competitive advantage. To succeed, modern companies need to develop the best education technologies and teaching philosophies. The intelligent agents can play a right role in the personalized education of online consumers, because intelligent agents can learn the consumers ’ learning preferences and styles and recommend the best learning strategies. Educated and informed consumers are smarter and more confident in their buying decisions. This paper investigates using intelligent agents to support consumer learning and proposes an agent-based consumer learning support framework.
Meeting the Zero Discharge Challenge for Produced Water (2004)

Abstract Reduced environmental impact is the goal when choosing produced water treatment technologies. On the Norwegian sector the method used for quantifying this impact is the Environmental Impact Factor, EIF. This method is computerized in a tool that calculates the environmental impact from each of a number of chemical component groups that are present in produced water. Re-injection of produced water is the preferred option, and mostly used when pressure support is required. This paper, however, describes new treatment technologies aimed at produced water being released to sea. The technologies are suitable for different produced water compositions. The components in the produced water that contribute to the environmental impact are mainly: aliphatic hydrocarbons, heavy aromatic compounds (PAH), alkylated phenols and man added production chemicals. At several Statoil operated fields the corrosion inhibitor and H&lt;sub&gt;2&lt;/sub&gt;S scavenger are giving a significant contribution. Several new technologies will be described. Statoil has had a leading role and actively participated in the development and qualification of most of these technologies. The results from this work will be presented. The technologies will include the CTour process, Epcon CFU, droplet coalescing technologies as well as new technologies to reduce discharge of production chemicals. The main conclusion is that knowledge is needed about which compounds contribute to the environmental impact of produced water before deciding which technology to use.
Structural modifications of camptothecin and effects on topoisomerase I inhibition (1992)

Camptothecin (1), a potent antitumor alkaloid, is known to inhibit topoisomerase I, an enzyme that relaxes supercoiled DNA. Modifications have been made to the B, D, and E rings of this natural product. Specifically, compounds 2-10 either have an ester moiety in place of the E ring lactone, a methyl ester attached to position 14, a saturated (or nonexistent) deaza B ring, or contain a combination of these permutations. We have conducted in vitro assays against the topoisomerase I relaxation reaction which verify the necessity for a lactone in the E ring. Furthermore, steric requirements at position 14 are shown to be crucial for activity, and planarity of the A and B rings of camptothecin is also implicated in the ability of the drug to inhibit topoisomerase I. Speculation on the nature of the drug binding pocket is presented.
Characterization of Crystalline Structure and Morphology of NiO Thin Films (2011)

We investigated the relation of sputtering powers with structural and morphological properties of nickel oxide (NiO) thin films. NiO thin films were fabricated by using an rf-reactive sputtering method on Si(100) substrates with a Ni target in a partial pressure of oxygen and argon. The films were deposited by various rf-sputtering powers from 100 to 200 W at room temperature. The phases and crystalline structures of the deposited films were investigated by using grazing incident X-ray diffraction (XRD). The thickness and surface morphology of the films were investigated by using a field emission-scanning electron microscopy (FE-SEM). The different sputtering conditions drastically affected the crystallinity and the surface morphology of NiO thin films. A combined analysis of the data obtained from X-ray diffraction and SEM images demonstrates that the preferred orientation of NiO films tends to grow from (111) to (200) direction as increasing the sputtering power, which can be explained by in terms of the surface energy along the indexing plane in an fcc structure. As increasing the rf power, lattice constants decreased from 4.26 to 4.20 angstroms and samples became high-quality crystals. Under our experimental condition, NiO films prepared at 150 W with 20% partial pressure of oxygen and 7 cm distance from the sample to the target show the best quality of the crystal.
Prone MammoPET Acquisition Improves the Ability to Fuse MRI and PET Breast Scans (2007)

PET MRI fusion is feasible and may assist in localizing lesions detected on either study. A more extensive study is underway to confirm the value of this fusion technique.
Enhanced Activation and Expansion of T Cells Using Mechanically Soft Elastomer Fibers (2018)

Practical deployment of cellular therapies requires effective platforms for producing clinically relevant numbers of high-quality cells. This report introduces a materials-based approach to improving activation and expansion of T cells, which are rapidly emerging as an agent for treating cancer and a range of other diseases. Electrospinning is used to create a mesh of poly(ε-caprolactone) fibers, which is used to present activating ligands to CD3 and CD28, which activate T cells for expansion. Incorporation of poly(dimethyl siloxane) elastomer into the fibers reduces substrate rigidity and enhances expansion of mixed populations of human CD4<sup>+</sup> and CD8<sup>+</sup> T cells. Intriguingly, this platform also rescues expansion of T cells isolated from CLL patients, which often show limited responsiveness and other features resembling exhaustion. By simplifying the process of cell expansion, compared to current bead-based platforms, and improving T cell expansion, the system introduced here may accelerate development of cellular immunotherapy.
The Stromboli geophysical experiment. Preliminary report on wide angle refraction seismics and morphobathymetry of Stromboli Island (Southern Tyrrhenian Sea, Italy) based on integrated offshore-onshore data acquisition (Cruise STR06 R/V URANIA) (2007)

The Stromboli geophysical experiment, performed to acquire onshore and offshore seismic data through a combined on-land and marine network, was finalized to reconstruct the
seismic tomography of the volcano and to investigate the deep structures and the location of magma chambers. A detailed swath bathymetry around the volcano has also been acquired by the R/V Urania Multibeam. In particular, high resolution bathymetry of the ’Sciara del Fuoco’ area allows to image the present-day seafloor setting of the area involved by the submarine slide of 2002-12-30. During the experiment wide angle refraction seismics was performed all around the Stromboli volcano by a 4 GI-GUN tuned array. The data were recorded by the permanent seismic network of the INGV and 20 temporary stations and 10 OBS deployed on the SE, SW and NE submerged flanks of the volcano after detailed morpho-bathymetric analysis.
Micelle formation of ionic surfactants in polar nonaqueous solvents (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicelle formation of ionic surfactants in polar nonaqueous solventsH. N. Singh, Syed M. Saleem, R. P. Singh, and K. S. BirdiCite this: J. Phys. Chem. 1980, 84, 17, 2191–2194Publication Date (Print):August 1, 1980Publication History Published online1 May 2002Published inissue 1 August 1980https://pubs.acs.org/doi/10.1021/j100454a016https://doi.org/10.1021/j100454a016research-articleACS PublicationsRequest reuse permissionsArticle Views2054Altmetric-Citations143LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Babesia microti Aldo-keto Reductase-Like Protein Involved in Antioxidant and Anti-parasite Response (2017)

The intraerythrocytic apicomplexan <i>Babesia microti</i> is the primary causative agent of human babesiosis, which is an infectious disease that occurs in various regions around the world. Although the aldo-keto reductases (AKRs) of this parasite have been sequenced and annotated, their biological properties remain unknown. AKRs are a superfamily of enzymes with diverse functions in the reduction of aldehydes and ketones. In the present study, we cloned the full-length cDNA of a <i>B. microti</i> aldo-keto reductase-like protein (BmAKR) and analyzed the deduced amino acid sequence of the BmAKR protein. This protein has a conserved AKR domain with an N-terminal signal sequence. <i>Bmakr</i> was upregulated on the 8th day after infection, whereas it was downregulated during the later stages. The recombinant protein of BmAKR was expressed in a glutathione <i>S</i>-transferase-fused soluble form in <i>Escherichia coli.</i> Western blot analysis showed that the mouse anti-BmAKR antibody recognized native BmAKR from a parasite lysate. Immunofluorescence microscopy localized BmAKR to the cytoplasm of <i>B. microti</i> merozoites in mouse RBCs in this study. <i>Bmakr</i> expression was significantly upregulated in the presence of oxidant stress. Atovaquone, a known anti-babesiosis drug, and robenidine, a known anti-coccidiosis drug, induced upregulation of <i>Bmakr</i> mRNA, thereby suggesting that <i>Bmakr</i> may be involved in anti-parasite drug response.
Preparation and utilization of molecularly imprinted silicas (1997)

Imprinted amorphous silicas tailored to adsorb selectively are presented. Their preparation–using molecular imprinting by the sol‐gel technique–is described and the influence of the conditions of preparation on the textures of the solids and on their molecular specificity discussed. Their degrees of enantiorecognition (using(–)‐menthol) are regiospecificity (using O‐cresol) are reported. The possibility of extension of this work to a large number of different molecular sizes and configurations is briefly considered.
Unravelling the molecular basis for light modulated cellulase gene expression - the role of photoreceptors in Neurospora crassa (2012)

Genome wide transcriptome analysis of photoreceptor mutants and evaluation of results by analysis of mutant strains identified several candidate genes likely to play a role in light modulated cellulase gene expression. Genes with functions in amino acid metabolism, glycogen metabolism, energy supply and protein folding are enriched among genes with decreased expression levels in the wc-1 and wc-2 mutants. The ability to properly respond to amino acid starvation, i. e. up-regulation of the cross pathway control protein cpc-1, was found to be beneficial for cellulase gene expression. Our results further suggest a contribution of oxidative depolymerization of cellulose to plant cell wall degradation in N. crassa.
The effect of reinforcing fibres in denture acrylics. (1989)

Since the early 1970's, various fibre reinforcement systems have been used to enhance the mechanical properties of denture base acrylics. The research conducted to date on fibre reinforcement systems for use with Poly(methylmethacrylate) (PMM) denture base material is reviewed and evaluated.
Partially coherent polarized atmospheric transmission characteristics and application technology research (2014)

Based on partially coherent polarized light transmission characteristics of the atmosphere, an intensity expression of completely coherent flashing light is derived from Andrews scale modulation method. According to the generalized Huygens-Fresnel principle and Rytov theory, the phase fluctuation structure function is obtained on condition that the refractive index profile in the atmosphere meet Von Karman spectrum, then get the arrival Angle fluctuation variance. Through the RMS beam width of gaussian beams in turbulent atmosphere, deviation angle formula of fully coherent gaussian beams in turbulence atmosphere is attained, then get the RMS beam width of partially coherent and derivation angle expression of GSM beam in turbulent atmosphere. Combined with transmission properties of radial polarized laser beam, cross spectral density matrix of partially coherent radially polarized light can be gained by using generalized huygens-fresnel principle. And light intensity and polarization after transmission can be known according to the unity of coherence and polarization theory. On the basis of the analysis model and numerical simulation, the simulation results show that: the light spot caused by atmospheric turbulence of partially coherent polarization will be superior to completely polarized light.Taking advantage of this feature, designed a new wireless suppression technology of atmospheric turbulence, that is the optimization criterion of initial degree of coherent light beam. The optimal initial degree of coherent light beam will change along with the change of atmospheric turbulence conditions,make control the beam’s initial degree of coherence to realize the initial degree of coherence of light beam in real time and dynamic control. A spatial phase screen before emission aperture of fully coherent light is to generate the partially coherent light, liquid crystal spatial light modulator is is a preferable way to realize the dynamic random phase. Finally look future of the application research of partially coherent light.
Silicon Mach-Zehnder waveguide interferometers operating at 1.3 μm (1991)

Mach-Zehnder waveguide interferometers have been fabricated in silicon and operation has been demonstrated at λ = 1.3 μm. The switching mechanism is based on the thermally induced variation of the refractive index of crystalline silicon. Modulation depths of 40% were obtained for switching powers of 30 mW and switching times of 50 μs.
Expression and developmental regulation of the NMDA receptor subunits in the kidney and cardiovascular system (2002)

Antagonists to the N-methyl-D-aspartate (NMDA) receptor bind to various extraneuronal tissues. We therefore assessed the expression of the main NMDA subunit, NR1, in various tissues. We demonstrate that NR1 appears to be most abundant in the rat kidney and heart. NR1 is present in total rat kidney, cortex, and medulla. Of the NR2 subunits, only the NR2C subunit protein is present in the kidney. The abundance of the NR1 subunit protein increases with kidney development. Both NR1 and NR2C are present in opossum kidney, Madin-Darby canine kidney, and LLC-PK(1) cells. Immunohistochemistry studies show that the NR1 subunit is present in the renal proximal tubule. NR1 is abundant in the atrium and ventricle but is also expressed in the aorta and pulmonary artery. The NR2 subunits are not expressed in the heart. NR1 subunit protein expression is constant throughout heart development. Finally, the NR1 subunit protein is expressed in heart cells (H9c2) grown in culture. These studies reveal the presence of the NMDA receptor in the kidney and the cardiovascular system.
Low-loss small-mode passive waveguides and near-adiabatic tapers in BK7 glass (1989)

A detailed study of the Ag/sup +/-Na/sup +/ ion-exchange in BK7 glass and fabrication of low-loss (<0.2 dB/cm at lambda /sub 0/=1.3 mu m) single-mode waveguides using this technique are discussed. By postbaking the extremities of small-mode-size straight-surface guides, 5-mm-long near-adiabatic fiber-compatible tapered transitions with total fiber-device insertion losses below 0.8 dB in 16-mm-long devices, including the tapers at both ends, have been demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Anhydro (“Cyclized”) Vitamin A<sup>1</sup> (1943)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnhydro ("Cyclized") Vitamin A1Edgar M. Shantz, John D. Cawley, and Norris D. EmbreeCite this: J. Am. Chem. Soc. 1943, 65, 5, 901–906Publication Date (Print):May 1, 1943Publication History Published online1 May 2002Published inissue 1 May 1943https://pubs.acs.org/doi/10.1021/ja01245a036https://doi.org/10.1021/ja01245a036research-articleACS PublicationsRequest reuse permissionsArticle Views136Altmetric-Citations66LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cytochalasin B and D dose-outflow facility response relationships in the cynomolgus monkey. (1982)

Total outflow facility was determined by two-level constant-pressure perfusion in cynomolgus monkeys for 30 to 40 min before and after intracameral infusion of cytochalasins B and D (CB, CD). CB and CD dose-facility response relationships were defined. CB doses of 0.1, 0.2, and 0.5 micrograms were subthreshold; 1, 2, 5 and 10 micrograms were effective, with 5 micrograms probably supramaximal. CD at 0.02 microgram was probably subthreshold; 0.1, 0.5, 1, 2.5, and 5 micrograms doses were effective, with 0.1 microgram being near or above maximum. Although the maximum effects of both agents were quantitatively similar, approximately doubling-starting facility, CD Was about 25 times more potent. Therefore, CB- and CD-induced facility increases are presumably due largely to interference with formation, structure, and function of actin filaments in the endothelial cells of the trabecular meshwork and inner wall of Schlemm's canal.
Editors' Preface (1971)

The material in this issue of Soviet Education was selected to inform the American educational and mathematical communities about the new Soviet mathematics curriculum for primary and secondary schools.