gebhart/patrepeval huggingface dataset:
Predicting Age Range of Users over Microblog Dataset (2013)

In this paper, we present the idea and methodologies on predicting the age span of users over microblog dataset. Given a user's personal information such as user tags, job, education, self-description, and gender, as well as the content of his/her microblogs, we automatically classify the user's age into one of four predefined ranges. Particularly, we extract a set of features from the given information about the user, and employ a statistic-based framework to solve this problem. The measurement shows that our proposed method incorporating selected features has an accuracy of around 71% on average over the training dataset.
Trans-dimensional Bayesian non-parametrics with spatial point processes (2003)

Abstract Point processes are a class of models where the notion of a variable dimension is inherent. The main part of this discussion is concerned with the application of marked point processes as prior models in non-parametric Bayesian function estimation, reformulating and revising earlier joint work with Elja Arjas and listing some other related work (Section 2).
Performance Analysis of Routing Metrics in Manet (2013)

Mobile Ad-hoc Network has become popular in recent years by many researchers. The objective of this paper is to implement the Multi Order Polynomial (MOP) in MANET. According to this paper , it is hypothesized that to work in MANET field , a novel approach can be used for computing routing metrics (like Packet Delivery Ratio, Normalized Routing Load, Average End To End Delay and many others). Although simulation is performed on number of routing protocols but in this paper only two routing protocols AODV(Ad-hoc On Demand Distance Vector) and DSR( Dynamic Source Routing) are tested through Network Simulator and results are obtained under different scenarios. The results obtained from simulation are validated using MOP( Multi order polynomial) expressions for the same and also computed some results and observed that the some expressions some facts are observed according to which order of polynomial performs better with minimum error rate, in this paper ninth order of polynomial expression generate the result, which is found to be satisfactory with maximum fitness value (1.0) for various routing metrics.
An Investigation of the Oncogenic Activity of Two Representative Epoxy Resins (1958)

An evaluation has been made of the oncogenic activity of two uncured epoxy resins. A liquid bisphenol-based epoxy resin produced no carcinomas in C3H mice when applied thrice weekly for 2 years in a concentration of 5 per cent. Carcinomas were produced by a liquid aliphatic epoxy resin at this level, but with a tumor potency of only 9 as compared with 264 for the positive control, 20-methylcholanthrene. The resins by subcutaneous injection in rats showed TT50 (time at which 50 per cent of the animals would be expected to carry tumors) of 100 and 157 weeks, and tumor potencies (10,000 divided by TT50 in days) of 14 and 9, respectively, as compared with a TT50 of 53 weeks and a tumor potency of 24 for 1,2,5,6-dibenzanthracene. Injection of either of these ressins, two solid bisphenol-based epoxy resins of higher molecular weight, or of diglycidyl resorcinol, poly(allyl glycidyl ether), or epoxodized soybean oil did not alter the incidence of pulmonary adenoma in strain A mice over a period of 16 weeks. Feeding 0.2 per cent of either liquid resin in the diet for 11 months also did not alter the incidence, nor did similar feeding for 16 weeks alter the incidence of induced tumors in mice pretreated with 20-methylcholanthrene.

On the basis of this study, the potential hazard of skin irritation or carcinogenesis would seem to be obviated by the ordinary good industrial hygiene practices.
3,4-Dihydroxypyrrolidine as Glycosidase Inhibitor (2009)

Glycosidases are involved in various important biological processes including digestion of starch in the intestine, oligosaccharide processing inside rough ER and Golgi apparatus, and degradation of glycoconjugates in lysosomes. It is apparent that inhibitors of this class of enzymes are useful in the investigation of biological functions of glycoconjugates. Furthermore, it is believed that these compounds are important as pharmaceuticals. The structures of glycosidase inhibitors can be categorized into two major classes; ground-state mimetics and transition-state mimetics. The former has a chair-shaped six-membered structure that mimics monosaccharides where ring oxygens are often replaced with other elements for an improved binding affinity. On the other hand, the latter possesses a somewhat distorted shape compared with the chair conformation of carbohydrates. One of the ways to derive such distortion is by the introduction of sp2 character into the six-membered ring, and another is by ring contraction to form a five-membered system for the transition-state mimetics. The functions of these transition-state mimetics are often unpredictable regarding inhibitory activity and enzyme specificity. This review focuses on such "difficult to predict" species in an attempt to extract information or common aspects for the future development of inhibitors of glycosidases based on transition-state mimetics.
Application-aware Traffic Management for OpenFlow networks (2016)

Software-Defined Networking (SDN) is an emerging networking paradigm aims to improve network management flexibility and efficiency. OpenFlow is the popular SDN de-facto standard, which has been prevalently adopted by both academia and industry for research and development purpose. OpenFlow provides rich programmable interface to network administrator to ease traffic monitoring and control. Because OpenFlow supports L4 network stack, it is feasible to provide application level traffic control by specifying TCP/UDP port number in flow rules. The major deficiency of the port-based traffic control is that it only provides the ability to control traffic from applications which have well-known TCP/UDP port numbers. In the case of port number change or dynamic (ephemeral) port allocation to an application, it is difficult to accurately control the application traffic. To be a solution, we propose an application-aware traffic management method by integrating Deep Packet Inspection (DPI) function with SDN controller. To show the feasibility, we design and implement Firewall and Bandwidth Manager applications based on the proposed management method. The applications perform on top of ONOS [1] controller, and FTP rate control example is shown to prove the feasibility of the proposed flow management method.
High performance AlGaInAs/InP strained MQW lasers for optical communication (2002)

The performance of 1300 nm uncooled FP devices based on compressive and tensile strained MQWs developed at Lasertron is reviewed. Results for 1550 nm FP lasers with compressively strained MQWs are also discussed. The possibility of designing this material system to fabricate DFB lasers with narrow spectral linewidth for long haul, high capacity and wide temperature range optical fiber communications is introduced. Up to date, conventional index and gain-coupled DFB laser structures are reviewed theoretically and experimentally in term of single mode yield and performances. Finally, we summarize the latest results of device characteristics and system performances based on Lasertron's AlGaInAs/InP strained MQW DFB lasers.
Beet necrotic yellow vein virus: different isolates are serologically similar but differ in RNA composition (1986)

SUMMARY Twelve isolates of beet necrotic yellow vein virus, agent of rhizomania in sugar beet, have been obtained from five European countries and the USA. The isolates were cloned and multiplied in the local lesion host Chenopodium quinoa. By ELISA, a close serological relationship was observed among all the isolates. The isolates differed, however, in the number of viral RNA species present (2, 3 or 4) and in the lengths of RNAs 3 and 4, the two smallest RNAs. A comparison of the symptoms induced by the different isolates in C. quinoa revealed a correlation between the presence of a full‐length RNA 3 (about 1850 nucleotides) and the appearance of severe chlorotic local lesions.
Panoramic camera using a mirror rotation mechanism and a fast image mosaicing (2002)

We describe a new panoramic camera that incorporates a 2-axis mirror rotation mechanism and a fast image mosaicing method. The mirror is positioned in front of the camera to move the camera's view. Partial images are taken during the mirror rotation. The image mosaicing method projects each partial image onto a projection surface around the rotation center of the mirror to produce a panoramic image. In this process, the projection center is shifted from the original viewpoint of the lens to the mirror rotation center to reduce discontinuity caused by motion parallax from the panoramic image. Our panoramic camera can provide accurate, continuous, high-resolution, large and endless (360 degrees wide) panoramic images with a short panoramic image acquisition time.
Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells. (1987)

Levels of histamine, chymase, and tryptase were assessed in preparations of dispersed human TC (tryptase+, chymase+) mast cells obtained from foreskin and of dispersed human T (tryptase+, chymase-) mast cells obtained from lung. Consistent with previous immunohistochemical results, extracts of T mast cells, the predominant mast cell type in lung (93% T and 7% TC mast cells), were deficient in human chymase (less than 0.3 microgram and 0.04 U/10(6) mast cells) but not tryptase (10.8 micrograms and 0.3 U/10(6) mast cells) by corresponding immunologic and enzymatic (suc-L-ala-ala-pro-phe-p-nitroanilide in the presence of aprotinin and tosyl-L-gly-pro-lys-p-nitroanilide in the presence of soybean trypsin inhibitor, respectively) assays. The minor presence of chymase activity in lung could be accounted for by the minor presence of lung TC mast cells. Extracts of TC mast cells, the predominant mast cell type (1% T and 99% TC mast cells) in foreskin, contained both proteases. However, TC mast cells from adult foreskin contained eightfold to 10-fold higher levels of chymase (4.5 micrograms and 1.01 U/10(6) mast cells) and twofold to threefold higher levels of tryptase (11.5 micrograms and 0.27 U/10(6) mast cells) than did TC mast cells from newborn foreskin (less than 0.6 microgram and 0.09 U of chymase and 35 micrograms and 0.62 U of tryptase/10(6) mast cells). In contrast, histamine levels were not significantly different in adult foreskin TC (1.9 microgram/10(6) mast cells), newborn foreskin TC (1.6 microgram/10(6) mast cells), and adult lung T (1.5 microgram/10(6) mast cells) mast cells. The relative ratio of each mediator in newborn foreskin mast cells to that in adult foreskin mast cells is highest for histamine, followed by tryptase and then chymase. Tryptase from TC and T mast cells had identical subunit compositions by Western blot analysis and similar apparent specific activities. This study extends the previously reported immunohistochemical distinction between human T and TC mast cells in tissue sections by direct quantitation of chymase and tryptase in dispersed preparations of T and TC mast cells.
Mechanochemical Synthesis of 0.9 Pb(Mg1/3Nb2/3)O3-0.1 PbTiO3from Mixed Oxides (1999)

Communication: Electrostrictive actuators and multilayer capacitors are two potential applications for PMN-PT (the title compound). Its preparation by mechanochemical reaction at room temperature as an ultrafine nanocrystalline powder of perov skite structure is reported here. The Figure shows a scanning electron micrograph of the fracture surface of PMN-PT following sintering at 1050 °C for 1 h
Juvenile arson intervention programs in Australia (2007)

Arson is a crime that is often committed by young people. An important strategy for preventing deliberate firesetting is intervention with young people who show an unhealthy interest in fire. Fire services in all Australian jurisdictions conduct juvenile arson intervention programs for such young people. These programs are usually run by specially trained firefighters, are carried out in the home of the young person with the involvement of the parents, and focus on the young person's behaviour and their family environment. Most programs are offered to children of all ages, and are not limited to those who have been involved in a criminal offence. The approaches that the programs take vary, but all include education about fire and cognitive behavioural approaches to problem behaviours. Most programs maintain strong linkages with mental health and other social services. To date, there has been limited evaluation of the programs, but anecdotal evidence suggests that they are viewed as successful. Formal, independent evaluation of programs should now be undertaken to ensure that they are effective in stopping firelighting behaviour among young people.
Differential uncoupling of chemoattractant receptors from G proteins in retinoic acid-differentiated HL-60 granulocytes (1993)

The ability of HL-60 cells differentiated with DMSO or retinoic acid (RA) to serve as models for polymorphonuclear leukocytes was examined. NaF and FMLP stimulated superoxide release from both groups of cells, but the response was attenuated in RA-differentiated cells. Isolated plasma membranes from DMSO-M and RA-differentiated (RA-M) cells were used to examine receptor and guanine nucleotide binding regulatory protein (G protein) expression. Ligand binding showed that formyl peptide and leukotriene B4 receptors were present in equal density on DMSO-M and RA-M. Formyl peptide receptors on RA-M failed to demonstrate high affinity binding sites. Both G alpha i2 and G alpha i3 were present in equal density on RA-M and DMSO-M by immunoblotting. FMLP, but not leukotriene B4, failed to stimulate guanosine 5'-(gamma-thio)triphosphate binding or GTP hydrolysis and guanine nucleotides failed to inhibit FMLP binding to RA-M. Addition of solubilized membranes containing normal formyl peptide receptors to solubilized RA-M reconstituted FMLP stimulated G protein activation, whereas addition of normal G proteins had no effect. We conclude that formyl peptide, but not leukotriene B4, receptors are uncoupled from G proteins in RA-differentiated HL-60 granulocytes. Although RA-differentiated cells are an inadequate model of neutrophil transmembrane signaling, they may provide a unique model by which to study the molecular requirements for formyl peptide receptor-G protein interactions.
Targeting AMPK Signaling as a Neuroprotective Strategy in Parkinson’s Disease (2018)

Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is characterized by the accumulation of intracellular α-synuclein aggregates and the degeneration of nigrostriatal dopaminergic neurons. While no treatment strategy has been proven to slow or halt the progression of the disease, there is mounting evidence from preclinical PD models that activation of 5'-AMP-activated protein kinase (AMPK) may have broad neuroprotective effects. Numerous dietary supplements and pharmaceuticals (e.g., metformin) that increase AMPK activity are available for use in humans, but clinical studies of their effects in PD patients are limited. AMPK is an evolutionarily conserved serine/threonine kinase that is activated by falling energy levels and functions to restore cellular energy balance. However, in response to certain cellular stressors, AMPK activation may exacerbate neuronal atrophy and cell death. This review describes the regulation and functions of AMPK, evaluates the controversies in the field, and assesses the potential of targeting AMPK signaling as a neuroprotective treatment for PD.
The Influence of Surface Condition and Environment on the Hydriding of Titanium (1979)

This paper discusses the conditions under which cathodically impressed or galvanically induced currents can cause hydriding of titanium. The oxide film that normally covers the surface of titanium is shown to be an effective barrier to hydrogen penetration. In environments where this film is unstable or where the oxide film has been damaged by abrasion, hydrogen absorption can occur. Experimental evidence and service case histories are cited.
Silencing of Mouse <i>Aprt</i> Is a Gradual Process in Differentiated Cells (2003)

Mouse Aprt constructs that are highly susceptible to DNA methylation-associated inactivation in embryonal carcinoma cells were transfected into differentiated cells, where they were expressed. Construct silencing was induced by either whole-cell fusion of the expressing differentiated cells with embryonal carcinoma cells or by treatment of the differentiated cells with the DNA demethylating agent 5-aza-2'-deoxycytidine. Induction of silencing was enhanced significantly by the presence of a methylation center fragment positioned upstream of a truncated promoter comprised of two functional Sp1 binding sites. Initial silencing of the Aprt constructs was unstable, as evidenced by high spontaneous reversion frequencies ( approximately 10(-2)). Stably silenced subclones with spontaneous reversion frequencies of <10(-5) were isolated readily from the unstably silenced clones. These reversion frequencies were enhanced significantly by treatment of the cells with 5-aza-2'-deoxycytidine. A bisulfite sequence analysis demonstrated that CpG methylation initiated within the methylation center region on expressing alleles and that the induction of silencing allowed methylation to spread towards and eventually into the promoter region. Combined with the induction of revertants by 5-aza-2'-deoxycytidine, this result suggested that stabilization of silencing was due to an increased density of CpG methylation. All allelic methylation patterns were variegated, which is consistent with a gradual and evolving process. In total, our results demonstrate that silencing of mouse Aprt is a gradual process in the differentiated cells.
Time-resolved spectral output of a doubly resonant cw optical parametric oscillator (1972)

Time-resolved spectra from the output of a doubly resonant parametric oscillator (DRO) pumped by a cw laser are presented. Single-cluster operation of the DRO is observed for low pump powers and a simultaneous multicluster operation at higher pump powers. For the multicluster operation, oscillation by higher-order modes is also detected.
Non‐ionic polystyrene latices in aqueous media (1987)

Abstract Colloidally stable non‐ionic polystyrene latices were prepared in aqueous media, with a narrow distribution of particle sizes, using a nonyl phenol polyethylene glycol condensate as the surface‐active agent, methoxy polyethylene glycol methacrylate as the comonomer‐stabiliser and ascorbic acid‐hydrogen peroxide as the initiator system. For comparison, a typical charge‐stabilised polystyrene latex was also prepared using an anionic surface‐active agent and potassium persulphate as the initiator. These latices were characterised using transmission electron microscopy, conductometric titration and microelectrophoresis. The stability of the latices to the addition of electrolyte was examined and also the stability to freeze‐thaw conditions. The glass transition temperatures of the latices were also determined.
Aerodynamic Evaluation of Miniature Trailing-Edge Effectors for Active Rotor Control (2011)

This work presents progress on a detailed aerodynamic evaluation of Miniature Trailing-Edge Effectors (MiTEs) for active rotor control.We begin with a 2D computational fluid dynamics (CFD) study focused on establishing the dependency of MiTE effectiveness and performance upon basic geometric parameters on a VR-12 airfoil.The CFD study demonstrated that a MiTE placed at 10% chord upstream of the trailing-edge and sized at approximately 1% chord is capable of delivering moment coefficient increments of approximately ±0.03, or the same moment authority as a conventional flap moving ±2.3 degrees.Wind tunnel experiments were performed on a model blade section equipped with an operational MiTE in order to validate the CFD results, and strong agreement was shown.Finally, a small set of 3D unsteady CFD simulations with prescribed blade motion of a rotor equipped with MiTEs were performed.Under high-thrust, moderate speed conditions, MiTEs deployed sinusoidally at 4/rev frequency were capable of reducing 4/rev integrated aerodynamic loads in the vertical direction by approximately 80%.normal force per unit span M -Mach number R -Rotor radius, ft Re c -Reynolds number based on chord U -Freestream Velocity V -Helicopter Flight Speed c -Blade chord h f -MiTE height f -Actuation frequency, Hz x -Coordinate in chordwise direction x f -Chordwise MiTE location y -Coordinate in lateral direction z -Coordinate in vertical direction Ω -Rotor speed, rad/sec  -Angle of attack, degrees κ -Reduced frequency, ωc/2U ω -Oscillation frequency, rad/s ø -Actuation phase shift, degrees
Evaluation of The Potential Use of Hybrid LC–MS/MS for Active Drug Quantification Applying The ‘Free Analyte Qc Concept’ (2017)

The 'free/active analyte QC concept' enables development of appropriate extraction conditions for correct active drug quantification by hybrid LC-MS/MS.
Comparative Outcomes of T-Cell–Depleted and Non–T-Cell–Depleted Allogeneic Bone Marrow Transplantation for Chronic Myelogenous Leukemia: Impact of Donor Lymphocyte Infusion (1999)

These results suggest that the combination of T-cell depletion and post-BMT DLI is a viable treatment option for patients undergoing allogeneic BMT for CML and should be prospectively compared with traditional forms of GVHD prophylaxis.
Distribution of gallium-67 in normal and hypotransferrinemic tumor-bearing mice. (1993)

The mechanism by which 67Ga accumulates in tumors is controversial. The most popular theory is that 67Ga binds to transferrin and gains access to cells by the transferrin receptor. However, substantial evidence suggests that uptake of 67Ga may not be universally mediated by transferrin in tumors. To determine whether transferrin is required for uptake of 67Ga in vivo, we compared the uptake of 67Ga by two types of implanted tumors and by normal tissues in normal and severely hypotransferrinemic strains of Balb/C mice. One type of tumor was strongly gallium-avid in normal mice; the other was not. Uptake of 67Ga by normal soft tissues was markedly less in hypotransferrinemic than in normal mice. Uptake of 67Ga by bone was equivalent in the two types of mice. For the more gallium-avid tumor, uptake of 67Ga was similar and the ratio of tumor-to-background activity was substantially higher in the hypotransferrinemic than in the normal mice. For the less gallium-avid tumor, uptake was significantly less in hypotransferrinemic than in normal mice. These data suggest that uptake of 67Ga by bone and by some tumors may be a transferrin-independent process.
Performance modeling and prediction of enterprise JavaBeans with layered queuing network templates (2005)

Component technologies, such as Enterprise Java Beans (EJB) and .NET, are used in enterprise servers with requirements for high performance and scalability. This work considers performance prediction from the design of an EJB system, based on the modular structure of an application server and the application components. It uses layered queueing models, which are naturally structured around the software components. This paper describes a framework for constructing such models, based on layered queue templates for EJBs, and for their inclusion in the server. The resulting model is calibrated and validated by comparison with an actual system.