gebhart/patrepeval huggingface dataset:
Role of hypercapnia in brain oxygenation in sleep-disordered breathing (2007)

Adaptive mechanisms may diminish the detrimental effects of recurrent nocturnal hypoxia in obstructive sleep apnea (OSA). The potential role of elevated carbon dioxide (CO2) in improving brain oxygenation in the patients with severe OSA syndrome is discussed. CO2 increases oxygen uptake by its influence on the regulation of alveolar ventilation and ventilation-perfusion matching, facilitates oxygen delivery to the tissues by changing the affinity of oxygen to hemoglobin, and increases cerebral blood flow by effects on arterial blood pressure and on cerebral vessels. Recent clinical studies show improved brain oxygenation when hypoxia is combined with hypercapnia. Anti-inflammatory and protective against organ injury properties of CO2 may also have therapeutic importance. These biological effects of hypercapnia may improve brain oxygenation under hypoxic conditions. This may be especially important in patients with severe OSA syndrome.
Effect of Age on Functional Outcomes After Stroke Rehabilitation (2002)

The small amount of variation that can be explained by age alone and the questionable clinical relevance of such a small effect suggest that there is no justification to deny patients access to rehabilitation solely because of advanced age.
Role of non‐selective adenosine receptor blockade and phosphodiesterase inhibition in cisplatin‐induced nephrogonadal toxicity in rats (2004)

1. It is well documented that cisplatin (CDDP) treatment increases the expression of adenosine A(1) receptors in both kidney and testes. However, the effect of adenosine at these receptors is controversial. Adenosine A(1) receptors have been documented to be involved in either cytoprotection or aggravation of nephrotoxicity. The aim of the present study was to examine the effect of the non-selective adenosine receptor inhibitor theophylline and the phosphodiesterase inhibitor pentoxifylline on CDDP-induced renal and testicular toxicity. 2. Male Wister rats were divided into six groups. Two control groups received plain drinking water and a third control group received theophylline 0.8 mg/mL in the drinking water for 2 weeks. One group of animals drinking plain water was injected intraperitoneally (i.p.) with pentoxifylline 50 mg/kg per day for 2 weeks. The remaining groups were treated in the same manner and received single dose of CDDP 7 mg/kg, i.p., 1 week after starting theophylline and pentoxifylline treatment and all animals were killed 1 week after CDDP treatment. 3. Rats treated with CDDP developed nephrotoxicity, as demonstrated by increased kidney and testes weight as a percentage of total bodyweight, blood urea nitrogen and serum creatinine levels and decreased serum calcium and albumin levels. In addition, CDDP treatment resulted in an increase in the production of malondialdehyde (MDA) and decreases in total nitrate/nitrite levels, as well as depletion of reduced glutathione (GSH) content and glutathione peroxidase (GPX) activity in both the kidney and testes. Administration of theophylline in the drinking water to CDDP-treated rats resulted in exacerbation of the indices of nephrotoxicity, depletion of GSH content and GPX activity levels, with increased MDA production and platinum accumulation in both the kidney and testes. However, pentoxifylline administration reduced CDDP-induced biochemical changes and reduced platinum accumulation in both organs. Histopathological examination of the kidney revealed that CDDP treatment produced multifocal tubular atrophy, atypical reparative changes of the tubular epithelium and marked tubular necrosis. Animals treated with the theophylline/CDDP combination showed extensive widespread damage with intratubular calcification. However, pentoxifylline treatment ameliorated the overt changes induced by CDDP treatment. 4. Theophylline exacerbates the deleterious effects of CDDP on rat kidney and testes. However, pentoxifylline alleviates CDDP-induced renal and testicular toxicity.
Perceptual linear predictive noise modelling for sinusoid-plus-noise audio coding (2004)

Sinusoidal coding of an audio subject to a bit-rate constraint, in general, results in a noise-like residual signal. This residual signal is of high perceptual importance; reconstruction of audio using the sinusoidal representation only typically results in an artificial sounding reconstruction. We present a new method, called perceptual linear predictive coding (PLPC), where the residual is encoded by applying LPC in the perceptual domain. This method minimizes a perceptual modelling error and therefore represents only residual components that are of perceptual relevance, while automatically discarding components masked by the sinusoidally coded part. Subjective listening tests show that PLPC performs significantly better than ordinary LPC as a sinusoidal residual coding technique. Furthermore, PLPC combined with a flexible segmentation and model order allocation algorithm leads to a significant gain in terms of R/D performance for fragments with fast changing characteristics.
Elevated Parathyroid Hormone-Related Peptide Associated With Lactation and Bone Density Loss (1996)

These data clearly support the hypothesis that PTHrP is an alternative mechanism associated with bone loss and recovery during and subsequent to lactation.
Satellite News Gathering : An Overview (1986)

This paper begins with a brief history of satellite communication, with particular regard to the early Ku-Band satellites and reviews some of the many experiments conducted by different organizations.
Twenty-nm Resolution Spin-polarized Scanning Electron Microscope (1994)

Journal Article Twenty-nm Resolution Spin-polarized Scanning Electron Microscope Get access Hideo Matsuyama, Hideo Matsuyama Advanced Research Laboratory, Hitachi, Ltd.Hatoyama, Saltama, 350-03 Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Kazuyuki Koike Kazuyuki Koike Advanced Research Laboratory, Hitachi, Ltd.Hatoyama, Saltama, 350-03 Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Electron Microscopy, Volume 43, Issue 3, June 1994, Pages 157–163, https://doi.org/10.1093/oxfordjournals.jmicro.a051100 Published: 01 June 1994 Article history Received: 09 February 1994 Accepted: 09 April 1994 Published: 01 June 1994
Genetic Analysis Identifies a Function for the <i>queC</i> ( <i>ybaX</i> ) Gene Product at an Initial Step in the Queuosine Biosynthetic Pathway in <i>Escherichia coli</i> (2005)

Queuosine (Q), one of the most complex modifications occurring at the wobble position of tRNAs with GUN anticodons, is implicated in a number of biological activities, including accuracy of decoding, virulence, and cellular differentiation. Despite these important implications, its biosynthetic pathway has remained unresolved. Earlier, we observed that a naturally occurring strain of Escherichia coli B105 lacked Q modification in the tRNAs. In the present study, we developed a genetic screen to map the defect in E. coli B105 to a single gene, queC (renamed from ybaX), predicted to code for a 231-amino-acid-long protein with a pI of 5.6. As analyzed by mobility of tRNA(Tyr) on acid urea gels and two-dimensional thin-layer chromatography of the modified nucleosides, expression of QueC from a plasmid-borne copy confers a Q+ phenotype to E. coli B105. Further, analyses of tRNA(Tyr) from E. coli JE10651 (queA mutant), its derivative generated by deletion of chromosomal queC (queA deltaqueC), and E. coli JE7325, deficient in converting preQ0 to preQ1, have provided the first genetic evidence for the involvement of QueC at a step leading to production of preQ0, the first known intermediate in the generally accepted pathway that utilizes GTP as the starting molecule. In addition, we discuss the possibilities of collaboration of QueC with other cellular proteins in the production of preQ0.
Evaluation of nickel and copper catalysts in biogas reforming for hydrogen production in SOFC (2017)

The solid oxide fuel cells (SOFC) enable the efficient generation of clean energy, fitting the current requirements of the growing demand for electricity and for the environment preservation. When powered with biogas (from digesters of municipal wastes), the SOFCs also contribute to reduce the environmental impact of these wastes. The most suitable route to produce hydrogen inside SOFC from biogas is through dry reforming but the catalyst is easily deactivated by coke, because of the high amounts of carbon in the stream. A promising way to overcome this drawback is by adding a second metal to nickel-based catalysts. Aiming to obtain active, selective and stable catalysts for biogas dry reforming, solids based on nickel (15%) and copper (5%) supported on aluminum and magnesium oxide were studied in this work. Samples were prepared by impregnating the support with nickel and copper nitrate, followed by calcination at 500, 600 and 800 oC. It was noted that all solids were made of nickel oxide, nickel aluminate and magnesium aluminate but no copper compound was found. The specific surface areas did not changed with calcination temperature but the nickel oxide average particles size increased. The solids reducibility decreased with increasing temperature. All catalysts were active in methane dry reforming, leading to similar conversions but different selectivities to hydrogen and different activities in water gas shift reaction (WGSR). This behavior was assigned to different interactions between nickel and copper, at different calcination temperatures. All catalysts were active in WGSR, decreasing the hydrogen to carbon monoxide molar ratio and producing water. The catalyst calcined at 500 oC was the most promising one, leading to the highest hydrogen yield, besides the advantage of being produced at the lowest calcination temperature, requiring less energy in its preparation.
Hémodynamique Glomérulaire et Excrétion de l'hémoglobine (1955)

SCOPUS: ar.j
Structure and Interactions of Charged Triblock Copolymers Studied by Small-Angle X-ray Scattering: Dependence on Temperature and Charge Screening (2011)

A series of thermo-responsive cationic triblock copolymers composed of methoxy-poly(ethylene glycol) (MPEG, hydrophilic), poly(N-isopropylacrylamide) (PNIPAAM, temperature sensitive), and poly((3-acrylamidopropyl) trimethyl ammonium chloride) (PN(+), cationic) has been investigated as a function of temperature and ionic strength. In the MPEG-b-PNIPAAM-b-PN(+) copolymers, the MPEG block length is constant, and the lengths of the PNIPAAM and PN(+) blocks are varied. The solubility of the PNIPAAM block decreases with increasing temperature, and the triblock copolymer thus provides the possibilities of studying micelles with both neutral and charged blocks in the micelle corona as well as the interplay between these two blocks as the electrostatic interactions are varied by addition of salt. Investigation of the systems by densitometry and small-angle X-ray scattering (SAXS) in a temperature range from 20 to 70 °C gave detailed information on the behavior both below and above the critical micelle temperature (CMT). A clear effect of the addition of salt is observed in both the apparent partial specific volume, obtained from the densitometry measurements, and the SAXS data. Below the CMT, the single polymers can be described as Gaussian chains, for which the repulsive interchain interactions, originating from the charged PN(+) block, have to be taken into account in salt-free aqueous solution. Increasing the salt concentration of the solution to 30 mM NaCl leads to an increase in the apparent partial specific volume, and the electrostatic repulsive interchain interactions between the single polymers vanish. Raising the temperature results in micelle formation, except for the copolymer with only 20 NIPAAM units. The SAXS data show that the polymer with the medium PNIPAAM block length forms spherical micelles, whereas the polymer with the longest PNIPAAM block forms cylindrical micelles. Increasing the temperature further above the CMT results in an increase in the micellar aggregation number for both of the polymers forming spherical and cylindrical micelles. The addition of salt to the solution also influences the aggregates formed above the CMT. Overall, the micelles formed in the salt solution have a smaller cross-section radius than those in aqueous solution without added salt.
Biological Denitrification of High Nitrate Processing Wastewaters from Explosives Production Plant (2011)

Wastewater samples originating from an explosives production plant (3,000 mg N l(-1) nitrate, 4.8 mg l(-1) nitroglycerin, 1.9 mg l(-1) nitroglycol and 1,200 mg l(-1) chemical oxygen demand) were subjected to biological purification. An attempt to completely remove nitrate and to decrease the chemical oxygen demand was carried out under anaerobic conditions. A soil isolated microbial consortium capable of biodegrading various organic compounds and reduce nitrate to atmospheric nitrogen under anaerobic conditions was used. Complete removal of nitrates with simultaneous elimination of nitroglycerin and ethylene glycol dinitrate (nitroglycol) was achieved as a result of the conducted research. Specific nitrate reduction rate was estimated at 12.3 mg N g(-1) VSS h(-1). Toxicity of wastewater samples during the denitrification process was studied by measuring the activity of dehydrogenases in the activated sludge. Mutagenicity was determined by employing the Ames test. The maximum mutagenic activity did not exceed 0.5. The obtained results suggest that the studied wastewater samples did not exhibit mutagenic properties.
Treatment of Traumatic Renal Arteriovenous Fistulas by Detachable Silicone Balloon Embolization (1979)

A new technique of detachable balloon arterial embolization allowed non-operative occlusion of 2 patients with post-traumatic arteriovenous fistulas in the kidney. This approach was successful in controlling hemorrhage with minimal loss of renal tissue.
On the nature of Pd species formed upon exchange of H-ZSM-5 with Pd(NH3)42+ and calcination in O2 (1999)

The chemistry of a high Pd loading Pd-H-ZSM-5 prepared by exchanging H-ZSM-5 with an aqueous solution of Pd(NH3)4(NO3)2 and calcined in O2 was studied by FTIR and TPD experiments. Acidic protons were found to readily exchange with Pd(NH3)22+ complexes and NH4+ ions arising from the partial decomposition of Pd(NH3)42+ possibly at the surface of H-ZSM-5 crystallites. The interaction of the Pd(II) ammine complexes with the MFI framework induced a strong absorption band at 928 cm-1 attributed to the vibration of distorted T–O bonds (T=Si, Al). Slow calcination in O2 at 653 K allowed the complete removal of NH3 ligands from Pd(NH3)2 entities and the decomposition of ammonium ions into protons. Despite the high Pd loading, no large PdO particles formed and the final oxidized Pd entities could be represented by the mean formula Pd(II)(OH)1.30.7+, suggesting the formation of isolated oxo and/or hydroxo Pd(II) complexes. A sharp IR band at 932 cm-1 indicated that most of these complexes were anchored to the oxygen atoms of the zeolite framework. On the contrary, calcination in O2 at 773 K led to the partial sintering of isolated Pd(II) species into large PdO particles. The possible formation of mobile Pd(OH)2 moieties in O2 at 773 K, migrating along the MFI channels, is discussed.
Origin of josephinite. (1979)

Josephinite is a nickel-iron alloy-bearing rock from Josephine County, southwestern Oregon. Josephinite had been thought to be the same as the metallic nickel-iron mineral awaruite (KRISHNARAO, 1962, 1964; RAMDOHR, 1950), but recently it has been shown to be a complex assemblage of minerals (BIRD and WEATHERS, 1975a). Although most samples of josephinite are somewhat altered, least-altered josephinite consists of several nickel-iron alloys, one intergrown with andradite garnet, an iron-cobalt alloy, and minor amounts of iron-nickel arsenides, iron-nickel-copper sulphides, and various unidentified phases. The intergrown metal-garent assemblage is apparently unique to josephinite. Alteration phases include serpentine minerals and magnetite. Josephinite occurs as detritus in several streams that originate and flow on the Josephine Peridotite; bedrock includes sheared serpentinite zones and basaltic to dioritic dikes within the peridotite. It is a reasonable assumption that the josephinite pebbles must be associated with one or more of these rocks; however, no unequivocal, large josephinite samples have been found within bedrock. BIRD and WEATHERS (1975a) proposed that because of its remarkable and apparently unique composition and textures, and its association with obducted mantle, josephinite has been derived from the mantle, conceivably the deep-mantle. Subsequently, DICK (1974), THORNBER and HAGGERTY (1976) and BOTTO and MORRISON (1976), following RAMDOHR (1950), argued that josephinite was formed by reduction of silicates, or sulphides, during serpentinization of the Josephine Peridotite. Currently, there are two views concerning the origin of josephinite: 1) josephinite is a product of low-temperature, synserpentinization processes and is comparable with awaruite 2) because of its mineral composition, textures, and rock associations, josephinite pre-dated serpentinization of the Josephine Peridotite (obducted ophiolite), was related to the origin of the Josephine Peridotite, and was derived from the primitive mantle, conceivably from as deep as the core-mantle boundary. Excesses of 3He, 21Ne and 129Xe have recently been found in josephinite and have been interpreted to indicate a mantle residence and, perhaps, a primordial age for this rock (DOWNING et al., 1977; BOCHSLER et al., 1978). We continue to propose a mantle derivation of josephinite; additionally, we suggest that josephinite was primitive material incorporated into the earth during earth accretion.
Exploring data mining implementation (2001)

article Exploring data mining implementation Author: Karim K. Hirji IBM Canada Ltd., Markham, Ont., Canada IBM Canada Ltd., Markham, Ont., CanadaView Profile Authors Info & Claims Communications of the ACMVolume 44Issue 701 July 2001pp 87–93https://doi.org/10.1145/379300.379323Published:01 July 2001Publication History 21citation4,070DownloadsMetricsTotal Citations21Total Downloads4,070Last 12 Months57Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Effects of modulus of elasticity of collagen sponges on their cell-mediated contraction in vitro (1998)

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1998.
Efficient Homolactic Fermentation by <i>Kluyveromyces lactis</i> Strains Defective in Pyruvate Utilization and Transformed with the Heterologous <i>LDH</i> Gene (2001)

A high yield of lactic acid per gram of glucose consumed and the absence of additional metabolites in the fermentation broth are two important goals of lactic acid production by microrganisms. Both purposes have been previously approached by using a Kluyveromyces lactis yeast strain lacking the single pyruvate decarboxylase gene (KlPDC1) and transformed with the heterologous lactate dehydrogenase gene (LDH). The LDH gene was placed under the control the KlPDC1 promoter, which has allowed very high levels of lactate dehydrogenase (LDH) activity, due to the absence of autoregulation by KlPdc1p. The maximal yield obtained was 0.58 g g(-1), suggesting that a large fraction of the glucose consumed was not converted into pyruvate. In a different attempt to redirect pyruvate flux toward homolactic fermentation, we used K. lactis LDH transformant strains deleted of the pyruvate dehydrogenase (PDH) E1alpha subunit gene. A great process improvement was obtained by the use of producing strains lacking both PDH and pyruvate decarboxylase activities, which showed yield levels of as high as 0.85 g g(-1) (maximum theoretical yield, 1 g g(-1)), and with high LDH activity.
An inhibitor of mammalian collagenase active at micromolar concentrations from an Actinomycete culture broth. (1987)

Anti-collagenase activity was detected in the culture supernatant of an Actinomycete strain S 4373. The molecule was purified by solvent extraction, medium pressure and high pressure reverse phase chromatography and finally by HPLC gel filtration. The pure product was analyzed by mass spectroscopy and was identified as actinonin, a known pseudopeptide antibiotic. The Ki was determined as 1.4 microM and this value was confirmed using pure synthetic actinonin.
Role of Exoproteins in Bacterial Keratitis (1999)

Department of Microbiology, Immunology, and Parasitology and Department of Ophthalmology, Louisiana State University Medical Center, New Orleans, Louisiana, U.S.A.
Trace element status in alcoholism before and during disulfiram treatment. (1990)

Trace element status was ascertained in 19 alcoholic patients under long-term treatment with disulfiram and in 12 alcoholic patients treated for the first time; the latter group was re-examined after four weeks of treatment. Both groups were compared to matched controls with a moderate alcohol intake. The copper/zinc ratio in serum was increased in the patients under long-term treatment, and a significant decrease occurred during the first four weeks of treatment in the second group. Blood lead was slightly increased in the second group, but not in the patients under long-term treatment. Blood cadmium was high in both groups, perhaps related to excessive tobacco smoking. Blood mercury concentrations were uniformly low. Urinary nickel excretion in the first group was above reference values, and an increase was seen in the second group during the treatment period. Although trace element concentrations in body fluids may not reflect tissue levels, the results support the notion that trace element balances are influenced by alcoholism and disulfiram treatment.
Anti-interference frequency detection algorithm of active frequency shift islanding detection (2012)

Aimed at the active frequency shift islanding detection of grid-connected PV generation system,the noise interference nearby zero crossing point of grid connected side signal to be measured brought adverse effects on the precision of zero-crossing measurement and PLL(phase-locked loop) frequency detection method,a triangle transformation frequency detection method with the function of noise suppression was proposed.Through optimal detction point interval evaluation and eliminating frequency singularity,the proposed method could avoid islanding misjudgement although grid connected side signal to be measured is interfered by the noise,system operation reliability was improved.The simulation model of system was established,which verified the the correctness of the method.
Sound source localization with binaural hearing aids using adaptive blind channel identification (2013)

This paper applies blind channel identification (BCI) to estimate direction of arrival (DOA) of sound sources with a pair of binaural hearing aids. It compares the Adaptive Eigenvalue Decomposition Algorithm (AEDA) with the Adaptive Principal Component Algorithm (APCA) for blindly estimating the impulse responses from target to hearing aids and these impulse responses are used to estimate DOA. This paper investigates how both the time difference and the level difference of the impulse responses can be used to estimate DOA, and the performance of both algorithms is evaluated for scenarios with different reverberation times, different SNR, and different source positions. The paper also evaluates the tracking behavior in a dual-talker scenario. The results show that AEDA's DOA performance suffers in the presence of noise and reverberation. APCA is fairly insensitive to noise, but it can only handle moderate levels of reverberation.