gebhart/patrepeval huggingface dataset:
Relative Permeability Hysteresis Effects in the Near-wellbore Region During Liquid Loading in Gas Wells (2010)

Abstract In oil and gas field operations, the dynamic interactions between reservoir and wellbore cannot be ignored, especially during transient flow in the near-wellbore region. A particular instance of transient flow in the near-wellbore region is the intermittent response of a reservoir that is typical of liquid loading in gas wells. Our previous numerical simulation study (Zhang et. al. 2009 and 2010) successfully captured the liquid backflow rates resulting from bottomhole pressure (BHP) oscillations typical of liquid loading, and emphasized their detrimental effect on gas production. This paper presents a numerical modeling effort to investigate the relative permeability hysteresis effects in the near-wellbore region during transient flow conditions for a synthetic, low permeability gas reservoir. Firstly, the previously validated "U-shaped" pressure profile along the reservoir radius was generated with an increased BHP from a starting steady-state flowing configuration. This pressure profile can lead to reinjection of the liquid phase into the reservoir. The BHP was then let to decrease, with a corresponding temporary recovery in gas productivity. With subsequent BHP oscillations, the flow direction was allowed to switch back and forth, which could represent a typical liquid loading scenario. The Killough method was used to calculate the relative permeability hysteresis during the various imbibitions and drainage processes. The results reveal that the hysteresis effect is negligible at a high-frequency alternation of imbibition and drainage in the near- wellbore region, and may therefore not be significant in liquid loading problems.
Obstruction or Progress? Plain Truths about India. (1928)

Obstruction or Progress? Plain Truths about India Get access Obstruction or Progress? Plain Truths about India. By Rai Vihari Mitra Bahadur. 1927. (Calcutta : The Author, 155 Lower Circular Road. 53 pp.) F. G. Pratt F. G. Pratt Search for other works by this author on: Oxford Academic Google Scholar Journal of the Royal Institute of International Affairs, Volume 7, Issue 1, January 1928, Page 61, https://doi.org/10.2307/3014874 Published: 01 January 1928
Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum (2004)

Dopaminergic and glutamatergic neurotransmissions in the striatum play an essential role in motor- and reward-related behaviors. Dysfunction of these neurotransmitter systems has been found in Parkinson's disease, schizophrenia, and drug addiction. Cyclin-dependent kinase 5 (CDK5) negatively regulates postsynaptic signaling of dopamine in the striatum. This kinase also reduces the behavioral effects of cocaine. Here we demonstrate that, in addition to a postsynaptic role, CDK5 negatively regulates dopamine release in the striatum. Inhibitors of CDK5 increase evoked dopamine release in a way that is additive to that of cocaine. This presynaptic action of CDK5 also regulates glutamatergic transmission. Indeed, inhibition of CDK5 increases the activity and phosphorylation of N-methyl-d-aspartate receptors, and these effects are reduced by a dopamine D1 receptor antagonist. Using mice with a point mutation of the CDK5 site of the postsynaptic protein DARPP-32 (dopamine- and cAMP-regulated phosphoprotein, molecular mass of 32 kDa), in the absence or in the presence of a dopamine D1 receptor antagonist, we provide evidence that CDK5 inhibitors potentiate dopaminergic transmission at both presynaptic and postsynaptic locations. These findings, together with the known ability of CDK5 inhibitors to prevent degeneration of dopaminergic neurons, suggest that this class of compounds could potentially be used as a novel treatment for disorders associated with dopamine deficiency, such as Parkinson's disease.
Pymetrozine, a Fast-Acting and Selective Inhibitor of Aphid Feeding.<i>In</i>-<i>situ</i>Studies with Electronic Monitoring of Feeding Behaviour (1997)

Pymetrozine, a pyridine azomethine compound, represents a novel insecticide with a selective activity against homopteran insects. It acts in a unique way: aphids are not knocked down on contact but seem to die of starvation. This implies an effect of pymetrozine on feeding behaviour. The aim of the present work was to elucidate how and at which step pymetrozine interferes with the complex mechanisms underlying phloem feeding. The effect of pymetrozine, applied in various ways, on different phases of stylet penetration and feeding activity of individual aphids was studied using the Electrical Penetration Graph technique (EPG). Initial choice experiments indicated that pymetrozine does not have a deterrent or antifeedant action. Topical application (150 ng pymetrozine mg-1 fresh weight) inhibited stylet insertion into the plant. When injected, less than 30 ng mg-1 was sufficient to produce the same effect. When pymetrozine was systemically applied via plant spraying or root uptake, aphids started feeding normally. After some time, however, they withdrew their stylets from the phloem and walked around with unaffected locomotion. At low doses aphids eventually recovered and resumed feeding. High doses, however, irreversibly disrupted feeding and prevented stylet reinsertion. Aphid motility was not affected up to an estimated haemolymph concentration of 1 mM pymetrozine. Aphids which eventually stopped feeding on pymetrozine-treated plants showed EPGs with distorted salivation/ingestion patterns. It is concluded that pymetrozine does not have a general toxic effect on aphids but selectively interferes with the nervous regulation of feeding behaviour which consequently results in death due to starvation after a few days. © 1997 SCI.
Ribosomal Genes in Escherichia coli (1986)

We have made rapid progress in recent years in identifying the genetic causes of many human diseases. However, despite this recent progress, our mechanistic understanding of these diseases is often incomplete. This is a problem because it limits our ...Read More
X-ray photoelectron spectroscopy of iodine-doped nonconjugated polymers (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTX-ray photoelectron spectroscopy of iodine-doped nonconjugated polymersAshutosh Chilkoti and Buddy D. RatnerCite this: Chem. Mater. 1993, 5, 6, 786–792Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://doi.org/10.1021/cm00030a012RIGHTS & PERMISSIONSArticle Views640Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (852 KB) Get e-Alerts Get e-Alerts
Inhibition of glycosidases by aldonolactones of corresponding configuration (1957)

1. The enzymic degradation of ovolecithin and certain other phosphoglycerides in ethereal solution by snake-venom phospholipase A is stimulated by Ca2+ ions. The optimum Ca2+ ion concentration varies between 40 and 80 /LM, when the lecithin concentration varies between 1*3 and 3-3 mM.
The cellular pathway of antigen presentation: biochemical and functional analysis of antigen processing in dendritic cells and macrophages. (1986)

The response of primed T cells to keyhole limpet haemocyanin (KLH) was used to compare the characteristics of antigen presentation by lymphoid dendritic cells, splenic and peritoneal macrophages. In a similar manner to macrophages, purified dendritic cells could be pulsed with antigen and subsequently fixed by brief glutaraldehyde fixation and still retain antigen presenting activity. Also, as previously reported for macrophages, presentation could be inhibited by chloroquine. These functional experiments suggested that the pathway of antigen presentation in dendritic cells and macrophages was similar or identical. However, biochemical studies, using radiolabelled antigen, showed that dendritic cells do not significantly degrade large proteins such as KLH to TCA-soluble form, but partially hydrolyse them to smaller peptide fragments. The significance of these results in terms of a model of the cellular pathways of antigen presentation is discussed.
Ilmstream: efficient multimedia streaming in decentralised distributed systems (2004)

Using the P2P-Model to implement multimedia streaming has been in the focus of research for some time. Many works have lead to very interesting results in the aspect of load balancing, caching and request scheduling. Only a few of the projects consider the decoupling of the neighbourhood relationship of the overlay network and the topology of the underlying infrastructure. In order to reduce the overall network load and to achieve point-to-point connections with better quality-of-service parameters we introduce IlmStream, a Peer-to-Peer Streaming System that forms geographical clusters of collaboratively streaming nodes. Keywords: multimedia streaming, Peer-to-Peer, geographical clusters
Polyphosphate Synthetic Activity of Polyphosphate:AMP Phosphotransferase in <i>Acinetobacter johnsonii</i> 210A (2004)

Polyphosphate:AMP phosphotransferase (PAP) has been identified as an enzyme that catalyzes the phosphorylation of AMP with inorganic polyphosphates [poly(P)] as phosphate donors. We found that the purified PAP of Acinetobacter johnsonii 210A has poly(P) synthetic activity. The PAP catalyzes the dephosphorylation of ADP and processively synthesizes poly(P) of 200 to 700 residues. Comparatively lower concentrations of MgCl(2) (20 mM) were required to obtain optimum poly(P) synthetic activity, whereas higher concentrations of MgCl(2) (100 mM) were necessary for optimum PAP activity. ADP is preferred over GDP as a phosphate donor for poly(P) synthesis. The K(m) and V(max) values for ADP in the poly(P) synthetic activity of PAP were 8.3 mM and 55 micromol min(-1) mg(-1), respectively. We concluded that the PAP of A. johnsonii 210A is a novel type of poly(P) kinase that uses ADP and GDP as substrates.
Association of the A561C E-selectin polymorphism with systemic lupus erythematosus in 2 independent populations. (2001)

In 2 of 3 populations studied, the E-selectin C allele was significantly more common in SLE than in controls. E-selectin may be a susceptibility gene to SLE in these populations. Its role in disease expression and longterm outcomes such as accelerated atherosclerosis requires further study.
Live Attenuated Varicella-Zoster Vaccine (1980)

Varicella-zoster (VZ) virus causes two diseases, varicella and zoster. Because it was recognized that, after varicella, latent VZ virus persisted in the host and because varicella was thought to be a milde disease, there was little impetus in North America to develop a live VZ vaccine. More recently, it has become apparent that currently available methods of prevention and treatment of severe varicella are not always efficacious. With the development of a live attenuated VZ vaccine by Takahashi and the successful use of the vaccine in immunocompromised children in Japan, there has been an increased interest in North America in immunization against varicella. In this article the natural history of VZ infections and the immunologic reactions to VZ virus are described, and the development and use of VZ vaccine in Japan are reviewed. Plans for trials of VZ vaccine in immunocompromised North American children are outlined. The major questions concerning the large-scale use of VZ vaccine are presented.
Analysis and design considerations of a buck converter with a hysteretic PWM controller (2004)

This paper presents an analysis and design considerations of a buck converter with a hysteretic PWM controller consist only of a comparator with a hysteresis. The ramp voltage superimposed on the output is supplied to the comparator from a simple RC network connected in parallel to the inductor winding. The steady-state output voltage and the switching frequency are initially examined taking the propagation delay in the control circuit into account. Next, the transfer functions of the output voltage for the input voltage and the load current are analyzed. The transient response of the output voltage for the step load change is also investigated by using the state equation. Furthermore, the design of the time constant of RC networks as a key parameter is discussed.
Rifampin and cell-mediated immune responses in tuberculosis. (1976)

To estimate the potential adverse consequences of rifampin therapy on cell-mediated immunity in tuberculosis, we measured in vitro lymphocyte responses to phytohemagglutinin, concanavalin A, pokeweed mitogen, and in vitro and in vivo responses to purified protein derivative tuberculin. Thirty-seven patients treated with therapeutic combinations containing rifampin were compared with 13 persons who had never received the drug. After initial improvement, responses to phytohemagglutinin became depressed in patients receiving rifampin for periods of 4 to 24 months. No significant changes were noted in lymphocyte responses to concanavalin A or pokeweed mitogen. In vitro and in vivo responses to purified protein derivative tuberculin were not altered. Because a favorable therapeutic outcome was achieved in all subjects, we concluded that rifampin does not have clinically significant immunosuppressive activity.
Full-rate full-diversity 2 x 2 space-time codes of reduced decoder complexity (2007)

Multiple-input multiple-output (MIMO) techniques have become an essential part of broadband wireless communications systems. For example, the recently developed IEEE 802.16e specifications for broadband wireless access include three MIMO profiles employing 2x2 space-time codes (STCs) and two of those are mandatory on the downlink of Mobile WiMAX systems. Conventional approaches to STC design are based on performance criteria such as coding gain, diversity gain, multiplexing gain, and ignore the decoder complexity. In this paper, we take an alternative approach and present a full-rate full-diversity 2x2 STC design leading to substantially lower complexity of the optimum detector than existing schemes. This makes the implementation of high performance full-rate codes realistic in practical systems.
Hyaluronic acid induces the release of growth factors from platelet-rich plasma (2016)

The levels of growth factors released by PRP on Day 5 were increased by the addition of HA. A mixture of PRP and HA may be a more effective therapy than PRP or HA alone for osteoarthritis and tendinopathy.
Intravenous Hypertonic Urea in the Management of Acute Angle-Closure Glaucoma (1961)

The clinical use of urea as an ocular hypotensive agent has only recently been reported in the ophthalmic literature although its effect upon the intraocular pressure was demonstrated experimentally over 45 years ago. In 1914, Hertel<sup>1</sup>reported that the intraocular pressure of rabbits was lowered by a 20% solution of urea injected intravenously. Subsequently, Fremont-Smith and Forbes<sup>2</sup>noted reduction of intracranial and intraocular pressure of cats after the intraperitoneal injection of hypertonic urea solutions, but little or no clinical application of these observations was made until Javid and Settlage<sup>3</sup>emphasized the effectiveness of hypertonic urea solutions in lowering cerebrospinal fluid pressure in neurosurgical patients. Bunge et al.<sup>4</sup>studied the effect of urea upon the intraocular pressure of monkeys; Javid<sup>5</sup>noted that the intraocular pressure of human subjects could be reduced by urea injected intravenously. However, it remained for Galin, Aizawa, and McLean<sup>6,7,8</sup>to demonstrate
Development of Polybenzimidazole-Based High-Temperature Membrane and Electrode Assemblies for Stationary and Automotive Applications (2008)

The program began on August 1, 2003 and ended on July 31, 2007. The goal of the project was to optimize a high-temperature polybenzimidazole (PBI) membrane to meet the performance, durability, and cost targets required for stationary fuel cell applications. These targets were identified in the Fuel Cell section (3.4) of DOE’s Hydrogen, Fuel Cells and Infrastructure Technologies Program Multi-Year Research, Development and Demonstration Plan. A membrane that operates at high temperatures is important to the fuel cell industry because it is insensitive to carbon monoxide (a poison to low-temperature fuel cells), and does not require complex water management strategies. Together, these two benefits greatly simplify the fuel cell system. As a result, the high-temperature fuel cell system realizes a cost benefit as the number of components is reduced by nearly 30%. There is also an inherent reliability benefit as components such as humidifiers and pumps for water management are unnecessary. Furthermore, combined heat and power (CHP) systems may be the best solution for a commercial, grid-connected, stationary product that must offer a cost benefit to the end user. For a low-temperature system, the quality of the heat supplied is insufficient to meet consumer needs and comfort requirements, so peak heaters or supplemental boilers are required. The higher operating temperature of PBI technology allows the fuel cell to meet the heat and comfort demand without the additional equipment. Plug Power, working with the Rensselaer Polytechnic Institute (RPI) Polymer Science Laboratory, made significant advances in optimizing the PBI membrane material for operation at temperatures greater than 160oC with a lifetime of 40,000 hours. Supporting hardware such as flow field plates and a novel sealing concept were explored to yield the lower-cost stack assembly and corresponding manufacturing process. Additional work was conducted on acid loss, flow field design and cathode electrode development. Membranes and MEAs were supplied by team member BASF Fuel Cell (formerly PEMEAS), a manufacturer of polymer and fiber. Additional subcontractors Entegris, the University of South Carolina (USC) Fuel Cell Center, and RPI’s Fuel Cell Center conducted activities with regard to stack sealing, acid modeling, and electrode development.
Evaluation of Color-Difference Formulae Based on Small Color Difference Data by Printed Sample (2009)

The small color-difference data obtained by printed sample were used to analyze and evaluate the color-difference forecast performance of CAM02-LCD, CAM02-SCD and CAM02-UCS color-difference formulae based on color appearance model, CIECAM02, the result was compared with the evaluation of CIE L*a*b*, CIEDE94, CMC (1:1), CMC (2:1) and CIEDE2000 classical color-difference formulae based on CIE L*a*b* color space. The conclusion indicates that performance of color-difference formulae based on CIECAM02 color appearance model precede the color-difference formulae based on CIE L*a*b* color space as a whole, but the color-difference forecast performance of each color-difference formula was disunity in different tone fields, further optimization will be necessary.
Cell-cycle-specific interaction of nuclear DNA-binding proteins with a CCAAT sequence from the human thymidine kinase gene. (1987)

Induction of thymidine kinase parallels the onset of DNA synthesis. To investigate the transcriptional regulation of the thymidine kinase gene, we have examined whether specific nuclear factors interact in a cell-cycle-dependent manner with sequences upstream of this gene. Two inverted CCAAT boxes near the transcriptional initiation sites were observed to form complexes with nuclear DNA-binding proteins. The nature of the complexes changes dramatically as the cells approach DNA synthesis and correlates well with the previously reported transcriptional increase of the thymidine kinase gene.
<title>Soft X-Ray Imaging Experiments With Charge Coupled Devices (CCDs) And Some Astronomical Applications</title> (1978)

We have evaluated the suitability of a CCD for use as a soft X-ray (E < 2 keV) image detector for astronomical and laboratory applications. The sensitivity of a currently available CCD to soft X-ray radiation has been measured. It was found to be comparable to that of other presently available X-ray image detectors. Back-illuminated CCDs which will be available soon offer significantly greater sensitivity, especially at longer X-ray wavelengths. Theoretical X-ray spectra of hot optically thin plasma sources such as those found in the solar corona or supernova remnants have been convolved with the response characteristics of the various CCDs, and minimum detectable fluxes have been determined as a function of plasma temperature. When operated at very low temperatures with optimal noise adjustment, the CCD may be used as an array of single X-ray photon detectors of excellent spectral and reasonable spatial resolution.
[A clinical study on the termination of early first trimester pregnancy in fifty cases by vaginal administration of 16,16-dimethyl-trans-delta 2-PGE1 methyl ester (ONO-802)]. (1988)

The results of the termination of 50 cases of early pregnancy (56 days) by vaginal suppositories containing 1 mg of 16,16-dimethyl-trans-delta2-PGE1 methyl ester (ONO-802) are as follows. The pregnant women were kept in the hospital for observation for 24 hours and treated with 1 suppository of ONO-802, 5 doses every 3 hours. Follow-up visits were obligatory within the 1st and 2nd weeks and within the 4th-6th weeks after treatment. Results of the treatment were judged at the 2nd follow-up visit, based on clinical course, pregnancy test, and gynecological examination. The rates of complete abortion, incomplete abortion, and failure of treatment were 76%, 6%, and 18%, respectively. The gastrointestinal side effects were tolerable. The complete abortion rate was only 76% lower than those reported in WHO multicenter studies but comparable with results obtained in Shanghai and Wuhan by using a similar protocol. Again, the successful rate in this group was lower than that reported in Shanghai by using d1-15 methyl PGF2alpha in combination with testosterone propionate, R2323, or Radix Trichosanthis for termination of early pregnancy. The authors believe that the effectiveness of ONO-802 for termination of early pregnancy may be improved by combined treatment with the above drugs. (author's modified)
SELFOC dielectric waveguides (1977)

It is shown that distortions appear in a signal propagated in a dielectric waveguide with a quadratic-law variation of the refractive index. These distortions are avoided if the refractive index varies in accordance with the hyperbolic cosine law.