gebhart/patrepeval huggingface dataset:
아동소설 속의 죽음과 성자의 고통: 『영원한 턱가족』과 『테라비시아 다리』의 경우 (2009)

Both Tuck Everlasting and Bridge to Terabithia are distinguished by their masterful treatment of the issue of death. Babbitt`s novel is intertwined with such mixed genres as folklore, fantasy, and realism, which, when taken together, contribute to an unique atmosphere. Together with the extension of self, this somewhat philosophical novel successfully delves into the meaning of immortality, as is show by the families of Tuck and Winnie. In addition, the novel emphasizes a blurred demarcation between absolute good and bad and thus reveals the complexity of human life. Paterson`s work is concerned with realism unlike that of Babbitt. The author focuses on the harsh reality and the impact of his friend`s death on the young protagonist, Jesse, rather than the meaning of death and life that Babbit explores. The no-nonsense tough world and the weight of suffering that the young boy felt to the bone are presented vividly and remarkably. Furthermore, this work represents the boy`s delicate feelings and internal transformation reliably, which greatly enhances the novel`s artistic merit. Both novel tend to acknowledge the impossibility of childhood`s innocence and deny an existence of an ideal, safe place for children. However, they concur in comforting the reader despite their treatment of human`s ultimate suffering-death, by providing an optimistic vision in their conclusion.
Solar vs diesel (2015)

Cellular networks in developing regions continue to rely heavily on diesel for energy to provide network coverage due to the paucity of reliable grid power which directly impacts the network's economic viability and long-term sustainability. At the other extreme, solar powered cellular installations have gained prominence but have faced their own adoption challenges including inability to provide adequate and reliable 24×7 power supply, need for large land footprints and lack of efficient power storage. In this paper, we perform a detailed economic cost analysis comparing diesel powered cellular networks with solar powered cellular networks. The key goal of this paper is to establish the cross-over boundary beyond which solar powered installations are better than diesel powered alternatives. We perform a detailed analysis based on actual diesel consumption data from a large telecom operator in a developing region. Using our model, we can also easily perform an extended analysis based on future projections on solar efficiencies and future cellular network designs.
Voltammetric Study of Arsenic (III) and Arsenic (V) in Ground Water of Hajigonj and Kalkini in Bangladesh (2008)

The speciation of arsenic in groundwater samples using Square Wave Anodic Stripping Voltammetry (SWASV), Differential Pulse Anodic Stripping Voltammetry (DPASV) and Normal Pulse Anodic Stripping Voltammetry (NPASV) are described. Good resolution of the species, arsenic (III) and arsenic (V) is achieved using SWASV. The reliability of the methods was checked by analyzing the total arsenic content of the samples by Hydride Generation Atomic Absorptioion Spectrophotometer and by analyzing prepared controlled laboratory standard solution. Since this technique is comparatively cheaper than other available techniques it could be a better analytical technique for arsenic speciation from water. In this study, the assessment of inorganic arsenic species in ground water of Kalkini (Madaripur) and Hajigonj (Chandpur) is reported. It shows that arsenic content in water in different locations is irregular. Most of the locations contain higher level of As(III) than As(V). The highest concentration of arsenic is found in Anayetnagor (554.46 ± 0.07 μg/L) of Kalkini and Raichar (562 ± 0.50 μg/L) of Hajigonj. However, the level of total arsenic and As(III) of most of the villages of the study areas are more than the WHO guideline value (50μg/L). Therefore a proper monitoring process should be evolved along with the development of methods to keep the water free from arsenic.
IoT-Based Intelligent Perception and Access of Manufacturing Resource Toward Cloud Manufacturing (2014)

Recently, cloud manufacturing (CMfg) as a new service-oriented manufacturing mode has been paid wide attention around the world. However, one of the key technologies for implementing CMfg is how to realize manufacturing resource intelligent perception and access. In order to achieve intelligent perception and access of various manufacturing resources, the applications of IoT technologies in CMfg has been investigated in this paper. The classification of manufacturing resources and services, as well as their relationships, are presented. A five-layered structure (i.e., resource layer, perception layer, network layer, service layer, and application layer) resource intelligent perception and access system based on IoT is designed and presented. The key technologies for intelligent perception and access of various resources (i.e., hard manufacturing resources, computational resources, and intellectual resources) in CMfg are described. A prototype application system is developed to valid the proposed method.
Inhibitors of Leucine-Rich Repeat Kinase 2 (LRRK2): Progress and Promise for the Treatment of Parkinson’s Disease (2015)

Mutations in the gene for leucine-rich repeat kinase 2 (LRRK2) have been linked to several familial and sporadic late-onset cases of Parkinson's disease. The cumulative data for the effects of mutant forms of this enzyme on neuronal degradation and the pathophysiology of Parkinson's disease create a compelling case for drug discovery based on inhibition of the mutant forms of LRRK2. This review focuses on structure-activity relationships for inhibitors of LRRK2 and the data supporting a potential role of these agents in treating Parkinson's disease.
The CICS programmer's desk reference (1987)

Cancer is the second leading cause of noncommunicable disease deaths in the world. In 2018, there were over 18 million new cancer cases and approximately 10 million people died from the disease globally. In 2019, almost two million new cases of cancer will be diagnosed in USA and over 600,000 people are expected to die from the disease. The incidence of cancer is expected to rise because of lifestyle changes and a rapidly aging population. Evidence suggests that early detection is critical to reducing cancer morbidity and mortality. In this paper, the development of an integrated smart wearable and biomarker detection system is proposed to help reduce cancer morbidity and mortality. The potential benefits and limitations of the system are discussed.
Transformation d’annotations en parties du discours et lemmes vers le format Universal Dependencies : étude de cas pour l’alsacien et l’occitan (2019)

International audience
Two Distinct Regions of Cyclophilin B Are Involved in the Recognition of a Functional Receptor and of Glycosaminoglycans on T Lymphocytes (1999)

Cyclophilin B is a cyclosporin A-binding protein exhibiting peptidyl-prolyl cis/trans isomerase activity. We have previously shown that it interacts with two types of binding sites on T lymphocytes. The type I sites correspond to specific functional receptors and the type II sites to sulfated glycosaminoglycans. The interactions of cyclophilin B with type I and type II sites are reduced in the presence of cyclosporin A and of a synthetic peptide mimicking the N-terminal part of cyclophilin B, respectively, suggesting that the protein possesses two distinct binding regions. In this study, we intended to characterize the areas of cyclophilin B involved in the interactions with binding sites present on Jurkat cells. The use of cyclophilin B mutants modified in the N-terminal region demonstrated that the 3Lys-Lys-Lys5 and 14Tyr-Phe-Asp16 clusters are probably solely required for the interactions with the type II sites. We further engineered mutants of the conserved central core of cyclophilin B, which bears the catalytic and the cyclosporin A binding sites as an approach to localize the binding regions for the type I sites. The enzymatic activity of cyclophilin B was dramatically reduced after substitution of the Arg62 and Phe67 residues, whereas the cyclosporin A binding activity was destroyed by mutation of the Trp128 residue and strongly decreased after modification of the Phe67 residue. Only the substitution of the Trp128 residue reduced the binding of the resulting cyclophilin B mutant to type I binding sites. The catalytic site of cyclophilin B therefore did not seem to be essential for cellular binding and the cyclosporin A binding site appeared to be partially involved in the binding to type I sites.
New frontiers in the pharmacological prevention of post-ERCP pancreatitis: the cytokines. (2003)

Acute pancreatitis is a major complication of endoscopic retrograde cholangiopancreatography (ERCP), its incidence varying with the indications for the procedure (<5% for the management of common bile duct stones and up to 20% in the case of sphincter of Oddi dysfunction) and also with events occurring during the ERCP such as acinarization and pancreatic sphincterotomy. If the triggering event of premature intra-acinar activation of trypsinogen is unknown, the acinar cell injury leads to oxidative stress, nuclear translocation of nuclear factor kappa B and subsequent transcription of chemo- and pro-inflammatory cytokines. These events are followed by chemoattraction and activation of monomacrophages, T lymphocytes and neutrophils which are responsible for acinar necrosis and amplification of the pro-inflammatory cascade. Finally, after amplification by Kupffer cells, systemic inflammatory response syndrome and multiple organ failure occur. All these events take place within a very short period of time, thus offering a very short therapeutic window during which it is theoretically possible to modulate the severity of human pancreatitis. Prophylactic immunomodulation of this pro-inflammatory cascade is attractive, using anti-inflammatory cytokines, specific inhibitors of pro-inflammatory cytokines or inhibitors of the nuclear translocation of the nuclear factor kappa B. Good results have been obtained in experimental models, reducing the acute pancreatitis severity and its systemic complications. The use of immunomodulators in the prevention of human post-ERCP pancreatitis is actually restricted to recombinant interleukin-10. Three of four randomized clinical trials, confirmed by a meta-analysis, have shown that prophylactic injection of recombinant interleukin-10 can significantly reduce the incidence of acute pancreatitis and may decrease the length of the hospital stay. The use of recombinant interleukin-10 in this indication has to be established in a multicenter prospective trial and we need to investigate the safety and efficacy of other immunomodulatory drugs and develop new specific targets.
Precipitation Strengthening in Al (Sc,Ti) Alloys (2003)

microscopy Three-dimensional atom probe (3DAP) and field-ion microscopies, together with microhardness measurements, are employed to analyze Al3(Sc1-xTix) precipitates in an Al-0.06at%Sc-0.06at.%Ti alloy aged at 300°C for different times. The field-ion microscope images show a relatively high number density of precipitates (estimated at (3±2)×1021ppt m-3) at the aging times analyzed. Concentration profiles obtained with 3DAP microscopy show that both Sc and Ti partition to these precipitates. While most of the Sc is contained in the precipitates, the Ti resides mainly in the matrix in solid solution. Consequently, the addition of Ti increases the hardness of this alloy only modestly over that of binary Al-Sc alloys. Additionally, the coherent Al3(Sc1-xTix) precipitates remain stable and coarsening-resistant up to aging times of at least 240 hr. at 300°C.
The roles of intrinsic disorder-based liquid-liquid phase transitions in the “Dr. Jekyll–Mr. Hyde” behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration (2017)

Pathological developments leading to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are associated with misbehavior of several key proteins, such as SOD1 (superoxide dismutase 1), TARDBP/TDP-43, FUS, C9orf72, and dipeptide repeat proteins generated as a result of the translation of the intronic hexanucleotide expansions in the C9orf72 gene, PFN1 (profilin 1), GLE1 (GLE1, RNA export mediator), PURA (purine rich element binding protein A), FLCN (folliculin), RBM45 (RNA binding motif protein 45), SS18L1/CREST, HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1), HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1), ATXN2 (ataxin 2), MAPT (microtubule associated protein tau), and TIA1 (TIA1 cytotoxic granule associated RNA binding protein). Although these proteins are structurally and functionally different and have rather different pathological functions, they all possess some levels of intrinsic disorder and are either directly engaged in or are at least related to the physiological liquid-liquid phase transitions (LLPTs) leading to the formation of various proteinaceous membrane-less organelles (PMLOs), both normal and pathological. This review describes the normal and pathological functions of these ALS- and FTLD-related proteins, describes their major structural properties, glances at their intrinsic disorder status, and analyzes the involvement of these proteins in the formation of normal and pathological PMLOs, with the ultimate goal of better understanding the roles of LLPTs and intrinsic disorder in the "Dr. Jekyll-Mr. Hyde" behavior of those proteins.
Feedback control for rotational movements in feature space (2014)

Abstract Synthesizing controllers for rotational movements in feature space is an open research problem and is particularly challenging because of the need to precisely regulate the character's global orientation, angular momentum and inertia. This paper presents feature‐based controllers for a wide variety of rotational movements, including cartwheels, dives and flips. We show that the controllers can be made robust to large external disturbances by using a time‐invariant control scheme. The generality of the control laws is demonstrated by providing examples of the flip controller with different apexes, the diving controller with different heights and styles, the cartwheel controller with different speeds and straddle widths, etc. The controllers do not rely on any input motion or offline optimization.
OPTIMIZATION AND CHARECTERIZATION OFINTRACELLULAR ORANGE FLUORESCENT PIGMENT FROM BACILLUS ENDOPHYTICUS (AVP-9(Kf527823) (2017)

Objective: Our study aimed to characterize and optimize the physico-chemical properties which render the high yield of intracellular orange fluorescent pigment (IOFP) and its antibacterial activity against clinical pathogens.Methods: Intracellular orange fluorescent pigment (IOFP) extracted from Bacillus endophyticus AVP-9(Kf527823) a rhizobacteria of chilli agricultural field using different solvent systems, fractioned by TLC and analyzed for absorption maxima. Purified pigment was screened for antimicrobial activity against clinical pathogen, Optimization of cultural conditions for maximizing the yield of pigment and compared the yield in different broth media.Results: AVP-9(Kf527823) showed circular, large orange color colonies which fluoresced orange under U. V light,. Intracellular pigment affectively extracted in acetone showed a bright fluorescent orange spot on the TLC plate, and absorption maxima at 493 nm. Antibacterial activity of isolated pigment showed highest zone of inhibition against E. coli and least to Pseudomonas. Maximum yield of the pigment was achieved in modified nutrient brot (MNB)h medium containing 2% w/v nutrient broth containing1% w/v glucose,1% w/v peptone and0.5% methionine at 35 Â°C and pH 7.0 with 48 h of incubation period. The yield was observed maximum in MNB. Compared to lactose broth, Tryptone soya broth and peptone water.Conclusion: Bright fluorescent orange pigment of Bacterium avp-9(Kf527823) with absorption maxima at 493 indicating that the pigment shows the characters of carotenoids. Yield maximum in MNB and its potential antibacterial activity needs further investigation for pharmaceutical applications.
Influence of Soil Structure on Direct Current Flowing Into Neutral Point of Power Transformer (2007)

When a high voltage direct current(HVDC) transmission system operates in ground-return mode, large currents will flow through the neutral earthed transformers near the HVDC grounding electrode, which may lead to a series of harmful results such as DC biases of transformers. Based on specified model, the influence of soil structure configuration on direct current flowing through transformer’s neutral point is analyzed. Complex soil structure with horizontal and vertical combined-layer model is taken into account. The results show that soil structure has notable effect on the direct current flowing through transformer’s neutral point. So when accurately calculating the direct current, the complexity of soil structure should be considered. The results also provide a theoretical reference for selection of substations near the HVDC ground electrode.
Banana-Shaped Compounds—A New Field of Liquid Crystals (1999)

Banana-shaped compounds form several new smectogenic phases specific to this class. Several two-dimensional phases have been observed, and these can exhibit very complex and beautiful optical textures (see Figure). These phases are reviewed and their structures investigated by not only X-ray diffraction and nuclear magnetic resonance measurements, but also dielectric and electrooptical experiments.
Alternate splicing of the rTS gene product and its overexpression in a 5-fluorouracil-resistant cell line. (1996)

rTS is a gene with convergent and overlapping transcription relative to thymidylate synthase (TS). Screening of a cDNA library has identified a second rTS RNA (rTSbeta) which is related to a previously described rTS RNA (rTSalpha). rTSbeta differs from rTSalpha by the insertion of an extra 116 nucleotides after base 128 of rTSalpha and an altered 3'-noncoding region such that rTSbeta RNA is not complementary to TS mRNA. rTSalpha and rTSbeta RNAs have open reading frames predicted to encode proteins of 361 and 416 amino acids, respectively. Antibody to rTSbeta protein detects two proteins of the predicted molecular weight in the H630 colon tumor cell line. rTSbeta is overexpressed 40-70-fold in a 5-fluorouracil-resistant H630 subline compared with 7-8-fold for TS and rTSalpha.
Synthesis and properties of the anti and syn isomers of dibenzothieno[b,d]pyrrole (2008)

A novel type of anti and syn isomers of a pentacyclic compound consisting of two thiophene rings and one pyrrole ring were efficiently synthesized from benzo[b]thiophene, and the anti isomer exhibits better charge transport and OFET properties compared with the syn isomer and its N-hexyl substitution.
Measurement of Gamma-Ray Production Double-Differential Cross Sections for the Spallation Reaction Induced by 0.8, 1.5 and 3.0GeV Protons (1998)

Gamma-ray production double-differential cross sections have been measured for 0.8, 1.5 and 3.0 GeV protons incident on C, Al, Fe, In and Pb targets. Gamma-rays were detected by NEZ13 liquid scintillators and gamma-ray signals were separated from neutron ones by a two-gate integration method. The photomultiplier-charge data of gamma-rays were unfolded with the FERDo-U code. Because of rather thick targets, effects of secondary particles on gamma-ray generation had to be removed and they were evaluated by particle transport calculations with the NMTC/JAERI, MCNP4A and HETC-KFAZ codes. Attenuation of gamma-rays in the target was calculated by the EGS4 code. Gamma-ray production cross sections were obtained in a gamma-ray energy range up to 60MeV. The experimental results were compared with calculated values by the HETC-KFAZ code. At gamma-ray energies up to 10MeV, the calculated cross sections agree with experimental data for the Fe, In, and Pb targets typically within a factor of two.
A Green, Scalable, One-Minute Synthesis of Benzimidazoles (2020)

Herein is reported a substantially improved synthesis of 2-substituted benzimidazoles by condensation of 1,2-diaminoarenes and aldehydes using methanol as the reaction medium. The developed method afforded moderate to excellent yields (33–96%) at ambient temperature, displays high functional group tolerance, is conducted open to air, and requires only one minute reaction time under catalyst- and additive-free conditions. Moreover, the efficient protocol permits scale-up to multi-gram scale synthesis of benzimidazoles and will become a method of choice when constructing such heterocyclic systems.
Real-Time Virtual Cables Based on Kinematic Simulation (2000)

We present an algorithm for the real-time simulation of virtual cables using inverse kinematics. A cable is\nmodeled by consecutive cylinder segments of equal size. The segments are connected by ball joints. At\nevery joint there is a spiral spring acting against the excursion of the joint. Given a start and an end\nposition of the cable, the algorithm calculates the shape of the cable that leads to minimal total energy.\nThe total energy is the sum of the potential energies of the segments and the elastic energies of the\nsprings. First, the algorithm calculates a cable with minimal total energy consisting of two segments. This\nis taken as a starting basis for the computation of a cable consisting of four segments. At each following\nstep, the number of segments is doubled and a new shape of the cable is calculated based on the solution\nof the previous step. The great advantage of this approach is the easy accommodation of the solution\nexactness to the available computation time. If the user of the VR application is moving the cable, he gets\na fast but rough feedback. If he stops moving it, he/she gets an exact shape.
Development of an Automated Continuous Clarification Bypass System To Remove Suspended Particulate Matter (2018)

An automated continuous clarification bypass system was developed to remove the suspended particulate matter (SPM) in the prereaction material. Compared to commercially available duty/standby filters, the proposed clarification bypass system is able to self-clean and does not require detachment of the filter and manual cleaning. In a stainless steel (SS) filter, the effects of flow direction, ultrasonication, and viscosity (=f(temperature)) were investigated. The data showed that the filtration performance could not meet the requirement of high clarification efficiency because of the high switch frequency (high switch frequency results from short filtration time before the filter fouls, which is indicated by increasing pressure differential across the filter). The deposition of crystals on the SS filter medium, and not the SPM, was the primary cause of the pressure build-up. Experiments with PTFE filter elements with comparable pore size and surface area to the stainless-steel filter were performed, and improved filtration performance (e.g., after the first cycle, the filtering time was 1–3 min with SS versus 30–60 min with PTFE) was observed. At the beginning of the SPM filtration process with the PTFE filter elements, three filtration mechanisms occurred (i.e., straining, impingement, and entanglement). As the filtration cake formed on the filter element surface, straining gradually dominated the filtration process, while the effects of impingement and entanglement became negligible.
LASIK-associated Dry Eye and Neurotrophic Epitheliopathy: Pathophysiology and Strategies for Prevention and Treatment (2008)

LASIK-induced dry eye and neurotrophic epitheliopathy are common complications of LASIK surgery. Optimization of the ocular surface prior to surgery decreases the incidence and severity of postoperative symptoms of the condition.