gebhart/patrepeval huggingface dataset:
A wavelet-based adaptive MSPCA for process signal monitoring and diagnosis (2005)

A novelty method of wavelet-based adaptive multiscale principal component analysis (MSPCA) is proposed for process signal acquisition and diagnosis. The wavelet transform is used to decompose the process signals and at the same time analyze the different scales signals based on multiresolution signal analysis, and then the signals are reconstructed in order to denoise and get rid of disturbances. The adaptive PCA algorithm is adopted to monitor and diagnose abnormal situations on the basis of the multiscale wavelet coefficients, analyze the slow and feeble changes of fault signals that can't be acquisition and monitored by conventional PCA. Furthermore, the theoretic framework and practical process of wavelet-based adaptive MSPCA algorithm about online process signals monitoring and diagnosis are also proposed. Experimental simulations and practical application results verify the validity and dependability of the proposed method.
Hyperparathyroidism and dialysis vintage. (2000)

Dialysis vintage is a key determinant of the severity of secondary hyperparathyroidism. Vintage and certain laboratory variables should be considered in the evaluation of therapies aimed at modifying the treated natural history of this disorder.
Integrated diffraction grating for lab-on-a-chip microspectrometers (2005)

Optical microspectrometers are potentially important components for improving the functionality of lab-on-a-chip systems used for detection and identification of cells and other biological material. For disposable and portable applications, monolithic integration of the microfluidic channels, optical waveguides and diffraction grating is desirable. This paper presents the design and simulation of a transmission grating that can be integrated with microfluidic channels for on-chip fluorescence detection. The grating design features two stigmatic points and large facet sizes that can be easily fabricated in low-cost polymers. Scalar simulations predict grating efficiencies greater than 74% for wavelengths from 500 nm to 700 nm in the -2 diffraction order.
260. 5-Chloro- and 5-bromo-1-methylbenzthiazole and cyanine dyes prepared from them (1936)

B. Beilenson and F. M. Hamer, J. Chem. Soc., 1936, 1225 DOI: 10.1039/JR9360001225
[Change of the skin electrical resistance in the right iliac region in acute appendicitis]. (1978)

An analytical expression for the carrier recovery time in semiconductor optical amplifiers (SOAs) that employ holding beams is presented. The amplifier model from which the expression is derived assumes a uniform carrier density along the SOA's length and that the signal and the holding beams both receive amplification. Simulations and experiments show that the expression predicts the recovery time well over a wide range of amplifier gains, holding beam powers, and configurations.
Oxygen radicals in cerebral ischemia (1992)

Superoxide production was measured as the superoxide dismutase (SOD)-inhibitable portion of nitro blue tetrazolium (NBT) reduction after cerebral ischemia-reperfusion in anesthetized cats equipped with cranial windows. Significant superoxide production was found in the early reperfusion period and continued for more than 1 h after ischemia. Superoxide was not detected in control animals not subjected to ischemia, during ischemia, and at 120 min of reperfusion. After ischemia, the vasoconstrictor response to arterial hypocapnia was reduced. This effect was prevented by pretreatment with SOD plus catalase or by deferoxamine. The response to topical acetylcholine was converted to vasoconstriction after ischemia. The normal vasodilator response reappeared spontaneously at 120 min of reperfusion. The vasodilator response to acetylcholine was preserved in animals pretreated with SOD plus catalase. Blood-brain barrier permeability to labeled albumin and horseradish peroxidase was increased after ischemia. These effects were minimized by pretreatment with SOD and catalase. We conclude that superoxide generation occurs during reperfusion after cerebral ischemia for a fairly long period and that superoxide and its derivatives are responsible at least in part for the vasodilation and the abnormal reactivity as well as for the increase in blood-brain barrier permeability to macromolecules seen after ischemia. Furthermore, the findings suggest that the agent responsible for the vascular abnormalities is hydroxyl radical generated via the iron-catalyzed Haber-Weiss reaction.
Measured Resection: An Outdated Technique in Total Knee Arthroplasty (2008)

Multiple methods may be used to determine correct femoral component rotation during TKA. Numerous reports document surgeon inability to precisely identify critical bone landmarks when deciding correct femoral component rotation using a measured resection methodology. While the author recommends using all available methods in combination, use of gap balancing provides a more accurate and reproducible way to obtain satisfactory flexion gap stability.
cDNA cloning and complete primary structure of skeletal muscle phosphorylase kinase (alpha subunit). (1988)

We have isolated and sequenced a cDNA encoding the alpha subunit of phosphorylase kinase from rabbit fast-twitch skeletal muscle. The cDNA molecule consists of 388 nucleotides of 5'-nontranslated sequence, the complete coding sequence of 3711 nucleotides, and 342 nucleotides of 3'-nontranslated sequence followed by a poly(dA) tract. It encodes a polypeptide of 1237 amino acids and a deduced molecular mass of 138,422 Da. Nearly half of the deduced amino acid sequence is confirmed by peptide sequencing. Seven positions of endogenously phosphorylated serine residues and autophosphorylation sites, identified by peptide sequencing, could be assigned. They cluster in a segment of only 60 amino acids. RNA blot hybridization analysis demonstrates a predominant RNA species of approximately equal to 4500 nucleotides and a less abundant RNA of 8700 nucleotides.
Pain Management: Part 1: Managing Acute and Postoperative Dental Pain (2010)

Safe and effective management of acute dental pain can be accomplished with nonopioid and opioid analgesics. To formulate regimens properly, it is essential to appreciate basic pharmacological principles and appropriate dosage strategies for each of the available analgesic classes. This article will review the basic pharmacology of analgesic drug classes, including their relative efficacy for dental pain, and will suggest appropriate regimens based on pain intensity. Management of chronic pain will be addressed in the second part of this series.
Back to Basics: The Perioperative Surgical Home (2015)

The Patient Centered Medical Home (PCMH) is designed to improve care for patients, decrease health care costs, and transform the way in which clinicians deliver primary care. The PCMH is a model for primary care delivery that encompasses comprehensive patient-centered care that is coordinated across all settings and provides accessible services and community support as needed with shorter wait times, enhanced hours, and around-the-clock telephone or electronic access for patient needs. In addition, providers use evidence-based practice and clinical decision support tools to provide the best possible care to patients. This article discusses how the model originated and provides a how-to guide and strategies for success in implementing this model of care.
<i>Ab initio</i>study of toroidal carbon nanotubes with encapsulated atomic metal loops (2007)

Toroidal carbon nanotubes can serve as hosts for encapsulated loops of atomic metal wires. Such composite structures have been analyzed using density functional theory for a semiconducting ${\mathrm{C}}_{120}$ torus encapsulating chains of Fe, Au, and Cu atoms. The sheathed metal necklaces form a zigzag structure and drop the highest occupied molecular orbital and/or lowest unoccupied molecular orbital band gap to less than $0.1\phantom{\rule{0.3em}{0ex}}\mathrm{eV}$. The iron composite is ferromagnetic with a magnetic moment essentially the same as that of bcc iron. The azimuthal symmetry of these toroidal composites suggests that they may offer novel electromagnetic properties not associated with straight, metal-encapsulated carbon nanotubes.
Screening of a Large Cohort of Leber Congenital Amaurosis and Retinitis Pigmentosa Patients Identifies Novel <i>LCA5</i> Mutations and New Genotype-Phenotype Correlations (2013)

This study was undertaken to investigate the prevalence of sequence variants in LCA5 in patients with Leber congenital amaurosis (LCA), early-onset retinal dystrophy (EORD), and autosomal recessive retinitis pigmentosa (arRP); to delineate the ocular phenotypes; and to provide an overview of all published LCA5 variants in an online database. Patients underwent standard ophthalmic evaluations after providing informed consent. In selected patients, optical coherence tomography (OCT) and fundus autofluorescence imaging were possible. DNA samples from 797 unrelated patients with LCA and 211 with the various types of retinitis pigmentosa (RP) were screened by Sanger sequence analysis of all LCA5 exons and intron/exon junctions. Some LCA patients were prescreened by APEX technology or selected based on homozygosity mapping. In silico analyses were performed to assess the pathogenicity of the variants. Segregation analysis was performed where possible. Published and novel LCA5 variants were collected, amended for their correct nomenclature, and listed in a Leiden Open Variation Database (LOVD). Sequence analysis identified 18 new probands with 19 different LCA5 variants. Seventeen of the 19 LCA5 variants were novel. Except for two missense variants and one splice site variant, all variants were protein-truncating mutations. Most patients expressed a severe phenotype, typical of LCA. However, some LCA subjects had better vision and intact inner segment/outer segment (IS/OS) junctions on OCT imaging. In two families with LCA5 variants, the phenotype was more compatible with EORD with affected individuals displaying preserved islands of retinal pigment epithelium. One of the families with a milder phenotype harbored a homozygous splice site mutation; a second family was found to have a combination of a stop mutation and a missense mutation. This is the largest LCA5 study to date. We sequenced 1,008 patients (797 with LCA, 211 with arRP) and identified 18 probands with LCA5 mutations. Mutations in LCA5 are a rare cause of childhood retinal dystrophy accounting for ∼2% of disease in this cohort, and the majority of LCA5 mutations are likely null. The LCA5 protein truncating mutations are predominantly associated with LCA. However, in two families with the milder EORD, the LCA5 gene analysis revealed a homozygous splice site mutation in one and a stop mutation in combination with a missense mutation in a second family, suggesting that this milder phenotype is due to residual function of lebercilin and expanding the currently known phenotypic spectrum to include the milder early onset RP. Some patients have remaining foveal cone structures (intact IS/OS junctions on OCT imaging) and remaining visual acuities, which may bode well for upcoming treatment trials.
Production of gamma-aminobutyric acid from alcohol distillery lees by Lactobacillus brevis IFO-12005. (2002)

Lactobacillus brevis IFO-12005 showed good growth in rice shochu distillery lees (kome shochu kasu). Almost all of the free glutamic acid (10.50 mM) in shochu kasu was converted to gamma-amino-butyric acid (GABA) within 2 d of stationary culture at 30 degrees C. The amount of GABA in the kome shochu kasu medium finally reached 10.18 mM. After centrifugation of the broth culture, the supernatant fraction was treated with a flocculation agent to form a clear solution, then passed through a column containing a synthetic adsorbents, SP-207 to remove the yellow pigment and flavors which are unnecessary from a sensory perspective. An economical and simple production process for GABA was established.
The actin cytoskeleton is required to elaborate and maintain spatial patterning during trichome cell morphogenesis in <i>Arabidopsis thaliana</i> (1999)

Arabidopsis thaliana trichomes provide an attractive model system to dissect molecular processes involved in the generation of shape and form in single cell morphogenesis in plants. We have used transgenic Arabidopsis plants carrying a GFP-talin chimeric gene to analyze the role of the actin cytoskeleton in trichome cell morphogenesis. We found that during trichome cell development the actin microfilaments assumed an increasing degree of complexity from fine filaments to thick, longitudinally stretched cables. Disruption of the F-actin cytoskeleton by actin antagonists produced distorted but branched trichomes which phenocopied trichomes of mutants belonging to the 'distorted' class. Subsequent analysis of the actin cytoskeleton in trichomes of the distorted mutants, alien, crooked, distorted1, gnarled, klunker and wurm uncovered actin organization defects in each case. Treatments of wild-type seedlings with microtubule-interacting drugs elicited a radically different trichome phenotype characterized by isotropic growth and a severe inhibition of branch formation; these trichomes did not show defects in actin cytoskeleton organization. A normal actin cytoskeleton was also observed in trichomes of the zwichel mutant which have reduced branching. ZWICHEL, which was previously shown to encode a kinesin-like protein is thought to be involved in microtubule-linked processes. Based on our results we propose that microtubules establish the spatial patterning of trichome branches whilst actin microfilaments elaborate and maintain the overall trichome pattern during development.
Can You Help Me with My Pitch? Studying a Tool for Real-Time Automated Feedback (2016)

In our pursue to study effective real-time feedback in Technology Enhanced Learning, we developed the Presentation Trainer, a tool designed to support the practice of nonverbal communication skills for public speaking. The tool tracks the user's voice and body to analyze her performance, and selects the type of real-time feedback to be presented. This paper describes an empirical study where we tested the effects of the Presentation Trainer's feedback on learners who used the tool while practicing for an elevator-pitch. Results from this study reveal that the feedback has a significant effect on the learners' motivation, confidence, self-awareness, and performance.
Infertility and age at first coitus: a possible relationship (1979)

Summary Reported age at first coitus was shown to be associated with incidence and degree of infertility. Infertility patients reported later first coital ages than gynaecological patients in a sample of 792 women seen in a major infertility service. Among the infertility patients, those who had never conceived presented a later first coital age than those who had previously conceived. Routine gynaecological patients reported the youngest first coital age of the groups studied.
A Performance Anomaly Detection and Analysis Framework for DBMS Development (2011)

Detecting performance anomalies and finding their root causes are tedious tasks requiring much manual work. Functionality enhancements in DBMS development as in most software development often introduce performance problems in addition to bugs. To detect the problems as soon as they are introduced, which often happens during the early phases of a development cycle, we adopt performance regression testing early in the process. In this paper, we describe a framework that we developed to manage performance anomalies after establishing a set of conditions for a problem to be considered an anomaly. The framework uses Statistical Process Control (SPC) charts to detect performance anomalies and differential profiling to identify their root causes. By automating the tasks within the framework we were able to remove most of the manual overhead in detecting anomalies and reduce the analysis time for identifying the root causes by about 90 percent in most cases. The tools developed and deployed based on the framework allow us continuous, automated daily monitoring of performance in addition to the usual functionality monitoring in our DBMS development.
Trellis-Coded Multiple-Pulse-Position Modulation for Wireless Infrared Communications (2004)

We present new trellis codes based on multiple-pulse-position modulation (MPPM) for wireless infrared communication. We assume that the receiver uses maximum-likelihood sequence detection to mitigate the effects of channel dispersion, which we model using a first-order lowpass filter. Compared to trellis codes based on PPM, the new codes are less sensitive to multipath dispersion and offer better power efficiency when the desired bit rate is large, compared with the channel bandwidth. For example, when the bit rate equals the bandwidth, trellis-coded (17 2)-MPPM requires 1.4 dB less optical power than trellis-coded 16-PPM having the same constraint length.
Studies in the elimination of substituted vinyl halides to acetylenes (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies in the elimination of substituted vinyl halides to acetylenesPaul F. Schuda and Martha R. HeimannCite this: J. Org. Chem. 1982, 47, 12, 2484–2487Publication Date (Print):June 1, 1982Publication History Published online1 May 2002Published inissue 1 June 1982https://doi.org/10.1021/jo00133a052RIGHTS & PERMISSIONSArticle Views389Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (517 KB) Get e-Alertsclose Get e-Alerts
Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes (1999)

Antiphospholipid antibodies (aPL) are associated with neurological diseases such as stroke, migraine, epilepsy and dementia and are thus associated with both vascular and non-vascular neurological disease. We have therefore examined the possibility that these antibodies interact directly with neuronal tissue by studying the electrophysiological effects of aPL on a brain synaptosoneurosome preparation. IgG from patients with high levels of aPL and neurological involvement was purified by protein-G affinity chromatography as was control IgG pooled from ten sera with low levels of aPL. Synaptoneurosomes were purified from perfused rat brain stem. IgG from the patient with the highest level of aPL at a concentration equivalent to 1:5 serum dilution caused significant depolarization of the synaptoneurosomes as determined by accumulation of the lipophylic cation [3H]-tetraphenylphosphonium. IgG from this patient as well as IgG from two elderly patients with high levels of aPL were subsequently shown to permeabilize the synaptosomes to labeled nicotinamide adenine dinucleotide (NAD) and pertussis toxin-ADP-ribose transferase (PTX-A protein) as assayed by labeled ADP-ribosylation of G-proteins in the membranes. No such effects were seen with the control IgG. aPL may thus have the potential to disrupt neuronal function by direct action on nerve terminals. These results may explain some of the non-thromboembolic CNS manifestations of the antiphospholipid syndrome.
Recombinant interferon gamma in psoriasis (1988)

<h3>To the Editor.—</h3> We read with great interest the recent article by Morhenn et al<sup>1</sup>entitled "Use of Recombinant Interferon Gamma Administered Intramuscularly for the Treatment of Psoriasis." Their results are in good agreement with those we reported previously,<sup>2,3</sup>showing that systemic treatmentof psoriasis with recombinant interferon-gamma (rIFN-gamma) (1) leads to the expression of HLA-DR antigen on keratinocytes in psoriatic lesions in vivo, (2) nevertheless does not clear psoriatic lesions, and (3) may increase the serum triglycéride level. In fact, these findings were presented at the Dermatopharmacology Symposium, at Stanford (Calif) in 1985, the Fourth International Symposiumon Psoriasis, at Stanford (Calif) in 1986, and at the on Psoriasis, at Stanford (Calif) in 1986, and at the 45th annual meeting of the American Academy of Dermatology, at New Orleans in 1986. Morhenn et al<sup>1</sup>injected rIFN-gamma intramuscularly and suggested that "intralesional administration of rIFN-gamma might prove advantageous."
INbusiness Eco Steps (2017)

Eco-friendliness and sustainability have been buzzwords in the salon industry for more than a decade, but being green is now more than just a trend, it's a responsibility, writes Rosa Anderson Jones.
The Complexes of Nickel(II), Palladium(II) and Platinum(II) with 2-Pyridinaldoxime<sup>1</sup> (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Complexes of Nickel(II), Palladium(II) and Platinum(II) with 2-Pyridinaldoxime1Ronald A. Krause and Daryle H. BuschCite this: J. Am. Chem. Soc. 1960, 82, 18, 4830–4834Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/ja01503a020https://doi.org/10.1021/ja01503a020research-articleACS PublicationsRequest reuse permissionsArticle Views367Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Near-Term Prospects for Semantic Technologies (2008)

Tor the past few years, the Semantic Web has been enjoying significant investment, mostly through research but to a lesser extent through start-ups and commercial projects. A major topic of discussion is where we can see those investments' results, so I asked several experts to consider what semantic technology will accomplish in the near future. The experts are from academia, venture capitalist firms, and companies focused on semantic technology, telecommunication, and Web 2.0.