gebhart/patrepeval huggingface dataset:
PWM A-CHB Converter Based on Trinary Multilevel Converter: Topology, Switching Algorithm, and Stability Analysis (2018)

A trinary multilevel converter uses a few heterogeneous H-bridge submodules (SMs) to synthesize an output voltage with multiple levels. Two major limitations of this converter are that it needs multiple dc sources and it cannot operate under pulsewidth modulation (PWM). This paper addresses these limitations by adding a low-voltage H-bridge SM to this converter and proposing a new switching algorithm. The resulting PWM-based asymmetric cascaded H-bridge converter uses only one dc source and synthesizes a high-quality output voltage. This improved converter can be a potential choice for real and reactive power support in power system applications. This paper also proposes methods for stability analysis and design of this converter. Experimental case studies evaluate the performance of the proposed converter for both standalone and grid-connected modes of operation.
<u>Semihydrogenaticn of Triple Bonds in 1-Alkeue Solutions</u> (1987)

Abstract Using 1-alkenes as solvent, catalytic reduction of alkynes in the presence of Lindlar's catalyst is achieved without risking over-reduction of terminal unsaturation.
Diminished forkhead box P3/CD25 double-positive T regulatory cells are associated with the increased nuclear factor-kB ligand (RANKL+) T cells in bone resorption lesion of periodontal disease (2007)

Periodontal disease involves multi-bacterial infections accompanied by inflammatory bone resorption lesions. The abundant T and B lymphocyte infiltrates are the major sources of the osteoclast differentiation factor, receptor activator for nuclear factor-kappaB ligand (RANKL) which, in turn, contributes to the development of bone resorption in periodontal disease. In the present study, we found that the concentrations of RANKL and regulatory T cell (T(reg))-associated cytokine, interleukin (IL)-10, in the periodontal tissue homogenates were correlated negatively, whereas RANKL and proinflammatory cytokine, IL-1beta, showed positive correlation. Also, according to the fluorescent-immunohistochemistry, the frequency of forkhead box P3 (FoxP3)/CD25 double-positive cells was diminished strikingly in the bone resorption lesion of periodontal disease compared to healthy gingival tissue, while CD25 or FoxP3 single positive cells were still observed in lesions where abundant RANKL+ lymphocytes were present. Very importantly, few or no expressions of FoxP3 by the RANKL+ lymphocytes were observed in the diseased periodontal tissues. Finally, IL-10 suppressed both soluble RANKL (sRANKL) and membrane RANKL (mRANKL) expression by peripheral blood mononuclear cells (PBMC) activated in vitro in a bacterial antigen-specific manner. Taken together, these results suggested that FoxP3/CD25 double-positive T(reg) cells may play a role in the down-regulation of RANKL expression by activated lymphocytes in periodontal diseased tissues. This leads to the conclusion that the phenomenon of diminished CD25+FoxP3+ T(reg) cells appears to be associated with the increased RANKL+ T cells in the bone resorption lesion of periodontal disease.
Magnetic anisotropy induced by magnetic field cooling in Ni3Mn alloys (1988)

The magnetic anisotropy of Ni3Mn alloys with various degrees of atomic order has been investigated by a torque magnetometry. By cooling down from 300 to 80 K in a magnetic field of 10 kOe, a unidirectional anisotropy Kd with a period of 360° was induced. The temperature dependence of this anisotropy can be expressed by exp(Q/T) from 50 to 20 K and by log(T) below 20 K. The magnitude of Kd was increased by a factor of 100 during cooling down from 50 to 4.2 K. Furthermore, the hysteresis loop at 4.2 K for a disordered alloy was shifted such that the easy direction of magnetization is that of the cooling magnetic field. They are discussed in terms of exchange anisotropy and the size distribution of clusters with antiferromagnetic coupling.
Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors: A report of four cases (2000)

Specific inhibitors of cyclooxygenase 2 (COX-2) have been approved for the treatment of osteoarthritis and rheumatoid arthritis. Unlike nonsteroidal anti-inflammatory drugs, specific COX-2 inhibitors do not inhibit platelet activation. However, these agents significantly reduce systemic production of prostacyclin. As a result, theoretical concerns have been raised that specific COX-2 inhibitors could shift the hemostatic balance toward a prothrombotic state. Patients with connective tissue diseases (CTD), who may be predisposed to vasculopathy and thrombosis, often have arthritis or pain syndromes requiring treatment with antiinflammatory agents. Herein we describe 4 patients with CTD who developed ischemic complications after receiving celecoxib. All patients had a history of Raynaud's phenomenon, as well as elevated anticardiolipin antibodies, lupus anticoagulant, or a history compatible with antiphospholipid syndrome. It was possible to measure a urinary metabolite of thromboxane A2 in 2 of the patients as an indicator of in vivo platelet activation, and this was markedly elevated in both. In addition, the patients had evidence of ongoing inflammation as indicated by elevated erythrocyte sedimentation rate, hypocomplementemia, and/or elevated levels of anti-DNA antibodies. The findings in these 4 patients suggest that COX-2 inhibitor-treated patients with diseases that predispose to thrombosis should be monitored carefully for this complication.
Vanadium-Phosphorus Catalysts Modified with Magnesium, Calcium and Barium (1997)

Vanadium-phosphorus catalysts specially modified with promotors can ensure an efficient and selective oxidation of C 4 hydrocarbons, even also that of butane to maleic anhydride. The catalysts with incorporated Mg, Ca or Ba ions provide a higher conversion of butane, yield of maleic anhydride, and selectivity for the latter compound than the unmodified catalyst. The conversion of butane and yield of maleic anhydride decrease with increasing basicity of the incorporated modifiers in the order: Mg, Ca, Ba, however, the selectivity of formation of maleic anhydride increases in the opposite order, which is interpreted by the idea that on the modified V-P catalysts the conversion of butane decreases faster than the yield of the anhydride with the natural basicity of the above-mentioned modifiers.
A Comparison of the Production of Ethanol between Simultaneous Saccharification and Fermentation and Separate Hydrolysis and Fermentation Using Unpretreated Cassava Pulp and Enzyme Cocktail (2012)

The processes of separate hydrolysis and fermentation (SHF) and simultaneous saccharification and fermentation (SSF) were employed using Saccharomyces cerevisiae for the production of ethanol from cassava pulp without any pretreatment. A combination of amylase, cellulase, cellobiase, and glucoamylase produced the highest levels of ethanol production in both the SHF and the SSF method. A temperature of 37 C, a pH of 5.0, and an inoculum size of 6% were the optimum conditions for SSF. For the batch process at a pulp concentration of 20%, ethanol production levels from SHF and SSF were the highest, at 23.51 and 34.67 g L 1 respectively, but in the fed-batch process, the levels of ethanol production from SHF and SSF rose to 29.39 and 43.25 g L 1 respectively, which were 25% and 24.7% higher than those of the batch process. Thus SSF using the fed-batch provided a more efficient method for the utilization of cassava pulp.
Correlation of surface microseismic event distribution to water production and faults mapped on 3D seismic data: A West Texas case study (2009)

The use of microseismic techniques to map hydraulic fracture treatments has increased dramatically in recent years. During this time, microseismic monitoring has grown from a technical curiosity into an established method for determining the spatial distribution and therefore effectiveness of well completions in tight reservoirs. While both surface and downhole microseismic monitoring techniques are widely used throughout the industry, surface microseismic methods have typically been met with more skepticism. We present a case study from West Texas in which surface microseismic results from two adjacent wells are validated by both 3D seismic and production data.
Terahertz metal nanofilm waveguides (2011)

A metal nanofilm waveguide for guiding terahertz (THz) wave is presented. We study the propagation characteristics of the symmetrical and unsymmetrical nanofilm waveguides theoretically. The results show that the symmetrical waveguide can transport terahertz wave with the loss of below 6×10-5 m-1 in the whole range of 0.1~3 THz. The loss of the unsymmetrical waveguide is much higher (below 0.21 m-1). The dispersions of both the two waveguides versus the frequency are very low. The propagation characteristics versus film thickness are also studied. We expect this waveguide to open the way for a new class of THz applications.
Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents (2003)

2-Methoxyestradiol (2-ME), a new anticancer agent currently in clinical trials, has been demonstrated to inhibit superoxide dismutase (SOD) and to induce apoptosis in leukemia cells through a free radical-mediated mechanism. Because the accumulation of superoxide (O(2)-) by inhibition of SOD depends on the cellular generation of O(2)-, we hypothesized that the endogenous production of superoxide may be a critical factor that affects the antileukemia activity of 2-ME. In the present study, we investigated the relationship between cellular O(2)- contents and the cytotoxic activity of 2-ME in primary leukemia cells from 50 patients with chronic lymphocytic leukemia (CLL). Quantitation of O(2)- revealed that the basal cellular O(2)- contents are heterogeneous among patients with CLL. The O(2)- levels were significantly higher in CLL cells from patients with prior chemotherapy. CLL cells with higher basal O(2)- contents were more sensitive to 2-ME in vitro than those with lower O(2)- contents. There was a significant correlation between the 2-ME-induced O(2)- increase and the loss of cell viability. Importantly, addition of arsenic trioxide, a compound capable of causing reactive oxygen species (ROS) generation, significantly enhanced the activity of 2-ME, even in the CLL cells that were resistant to 2-ME alone. These results suggest that the cellular generation of O(2)- plays an important role in the cytotoxic action of 2-ME and that it is possible to use exogenous ROS-producing agents such as arsenic trioxide in combination with 2-ME to enhance the antileukemia activity and to overcome drug resistance. Such a combination strategy may have potential clinical applications.
The Schlafen Family of Proteins and Their Regulation by Interferons (2013)

The Schlafen (SLFN) family of proteins includes several mouse and human members. There is emerging evidence that members of this family of proteins are involved in important functions, such as the control of cell proliferation, induction of immune responses, and the regulation of viral replication. These proteins span across all species with great diversity, with 10 murine and 5 human isoforms. Recent work has established that mouse and human SLFN proteins are regulated by interferons (IFNs). Several Slfn genes were shown to be induced as classical interferon-stimulated genes, and emerging evidence suggests that these proteins play important roles in the growth inhibitory and antineoplastic effects of IFNs. In the current review, the known properties of mouse and human SLFNs are reviewed, and the implications of their emerging functions are discussed.
A Multichannel WDM-PON System with Port Agnostic Tunable SFP+ Transceiver Modules (2018)

We demonstrate a WDM-PON system with port agnostic tunable SFP+ transceiver modules. With low-frequency envelope-modulated message channel, error-free data transmission is achieved at 8.5 Gbps with a sensitivity better than -19 dBm.
An unusual Antarctic chiton (1961)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Electrospun Conducting Polymer-Based Sensors for Advanced Pathogen Detection (2008)

This paper focuses on the development of conducting polymer hybrid sensors for pathogen detection for advanced medical diagnostics. Using the electrospinning technique, polyaniline hybrids were developed for the detection of gas and for pH monitoring to determine the suitability of these sensors for exhaled human breath analyses. Results show that electrospun hybrids based on leucoemeraldine based polyaniline exhibit sensitivity to down to 1 ppm and for the first time, using emeraldine salt polyaniline, demonstrate a conductimetric response to changes in the headspace of aqueous solutions of varying pH. This manuscript discusses the response of these hybrid systems to varying concentrations of pH and NO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> .
Study on Reuse of Returned Concrete (1997)

To reuse concrete returned from job sites, the method to remain the fresh properties of the returned concrete for a long time was studied by stopping cement hydration temporarily and adding an activator to the concrete next day to reuse in the same manner as an ordinary concrete. At the same time of adding an stabilizer, a superplasticizer was added to obtain the consistency with slump of 22cm or so. As a result, the slump of approximately 18cm was obtained next day. The reactivated concrete exhibits equal bleeding, compressive strength, freeze resistance, and change in length to ordinary concrete. The setting time of returned concrete reactivated retards as stabilized concrete retards. However, the setting time of the reactivated concrete mixed with returned concrete and new concrete becomes equal to that of ordinary concrete.
A multimedia workflow-based collaborative engineering environment for oil & gas industry (2004)

In this paper we discuss the scenario of Petroleum Engineering projects of Petrobras, a large Brazilian governmental oil & gas company. Based on this scenario, we propose a set of application requirements and system architecture to guide the construction of a Collaborative Engineering Environment (CEE) for assisting the control and execution of large and complex industrial projects in oil and gas industry. The environment is composed by the integration of three different technologies of distributed group work: Workflow Management System (WfMS), Multimedia Collaborative System (MMCS) and Collaborative Virtual Environments (CVE).
Self-assembled arginine-coated peptide nanosheets in water (2013)

The surfactant-like peptide (Ala)(6)(Arg) is found to self-assemble into 3 nm-thick sheets in aqueous solution. Scanning transmission electron microscopy measurements of mass per unit area indicate a layer structure based on antiparallel dimers. At higher concentration the sheets wrap into unprecedented ultrathin helical ribbon and nanotube architectures.
X-ray powder diffraction from carbon nanotubes and nanoparticles (1995)

We report detailed x-ray powder-diffraction measurements on a sample consisting of \ensuremath{\sim}60% carbon nanotubes and \ensuremath{\sim}40% carbon nanoparticles. These measurements demonstrate the existence of short-range interlayer stacking correlations. Our calculations show that such correlations should not be observable in idealized models of nanotubes. The observation of short-range interlayer correlations can be explained if many of the nanotubes and nanoparticles have polygonal cross sections, largely consisting of flat regions having graphitic interlayer correlations. This polygonization is almost certainly driven by the van der Waals interactions responsible for the ABAB stacking in crystalline graphite.
A New Approach: Patient Portals for Primary Intervention (2014)

N/A
Spectral Theory of Physical and Chemical Binding<sup>,</sup> (1996)

A spectral method which provides unified quantum mechanical descriptions of both physical and chemical binding phenomena is reported for constructing the adiabatic electronic potential energy surfaces of aggregates of atoms or other interacting fragments. The formal development, based on use of a direct product of complete sets of atomic spectral eigenstates and the pairwise-additive nature of the total Hamiltonian matrix in this basis, is seen to be exact when properly implemented and to provide a separation theorem for N-body interaction energies in terms of response matrices which can be calculated once and for all for atoms and other fragments of interest. Its perturbation theory expansion provides a generalization of familiar (Casimir−Polder) second-order pairwise-additive and (Axilrod−Teller) third-order nonadditive interaction energies, expressions which are recovered explicitly in the long-range-dipole expansion limit. A program of ab initio computational implementation of the formal development is described on the basis of use of optimal (Stieltjes) representations of complete sets of discrete and continuum atomic spectral states, which provide corresponding finite-matrix representations of the Hamiltonian. The widely employed pairwise-additive approximation to nonbonded N-body interaction energies is obtained from these implementations in appropriate limits. Additionally, the development clarifies and extends rigorously diatomics-in-molecules approaches to potential-surface construction for bonding situations, includes the effects of state mixing and charge distortion missing from semiempirical and perturbation approximations commonly employed in theoretical studies of collision broadening and trapped-radical spectroscopy, and encompasses and demonstrates equivalences among these apparently dissimilar approaches in appropriate limits. Large non-pairwise-additive contributions to the lowest-lying potential energy surfaces are found in illustrative studies of the structure and spectra of physically bound Na−ArN cryogenic clusters.
Recombinant human bactericidal/permeability-increasing protein (rBPI23) is a universal lipopolysaccharide-binding ligand (1994)

A recombinant 23-kDa protein (rBPI23) derived from human bactericidal/permeability-increasing protein (BPI) possesses potent endotoxin-neutralizing abilities in vitro and in vivo. Binding of rBPI23 to those endotoxins (lipopolysaccharides [LPSs]) encountered clinically would be a prerequisite for efficacy in decreasing mortality among patients suffering from gram-negative sepsis and shock, a disease state in which an etiological role for LPS has been implicated. rBPI23 binds well to lipid A (n = 7), to rough-mutant O-chain-deficient LPS (n = 18, Re to Ra chemotypes), to lipid A-core covalently linked to the O chain, to LPSs from clinically relevant serotypes (n = 100), and to bacterial cells (n = 88) of Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae, the species most often implicated in clinical gram-negative sepsis and shock. Significant binding of rBPI23 to these antigens took place at rBPI23 concentrations of 1 to 500 ng/ml (median, 16 to 32 ng/ml). Binding did not involve 3-deoxy-D-manno-octulosonate of the inner core. Determining the exact epitope recognized by rBPI23 would require further studies with synthetic lipid A substructures. The demonstrated ability of rBPI23 to universally bind LPS provides a sound basis for further testing of its endotoxin-neutralizing abilities, including clinical trials.
Fabrication and Testing of a Medical Surgical Instrument Capable of Detecting Simulated Embedded Lumps (2007)

A novel endoscopic grasper is being fabricated and tested. This grasper can be used in detecting lumps or tumors in biological tissues. The detailed fabrication process of the tactile sensor has been discussed. Custom-made sensors were integrated with the jaws of the endoscopic grasper and objects with known tactile features were tested by the designed grasper. Different experiments were performed with the system in order to determine both the position and the size of the lumps or inclusions located in the soft elastomeric media. The average discrepancy between the experimental and theoretical simulations was found to be less than 15%.
Effects of dietary fiber supplementation on glycemic control in dogs with alloxan-induced diabetes mellitus (1991)

The effect of a high insoluble-fiber (IF) diet containing 15% cellulose in dry matter, high soluble-fiber (SF) diet containing 15% pectin in dry matter, and low-fiber (LF) diet on glycemic control in 6 dogs with alloxan-induced insulin-dependent diabetes mellitus was evaluated. Each diet contained greater than 50% digestible carbohydrate in dry matter. A crossover study was used with each dog randomly assigned to a predetermined diet sequence. Each dog was fed each diet for 56 days. Caloric intake was adjusted weekly as needed to maintain each dog within 1.5 kg of its body weight measured prior to induction of diabetes mellitus. All dogs were given pork lente insulin and half of their daily caloric intake at 12-hour intervals. Mean (+/- SEM) daily caloric intake was significantly (P less than 0.05) less when dogs consumed the IF diet vs the SF and LF diets (66 +/- 3 kcal/kg, 81 +/- 5 kcal/kg, and 79 +/- 4 kcal/kg, respectively). Serum alkaline phosphatase activity was significantly (P less than 0.05) higher when dogs consumed the LF diet vs the IF and SF diets (182 +/- 37 IU/L, 131 +/- 24 IU/L, and 143 +/- 24 IU/L, respectively). Mean postprandial plasma glucose concentration measured every 2 hours for 24 hours, beginning at the time of the morning insulin injection, was significantly (P less than 0.05) lower at most blood sampling times in dogs fed IF and SF diets, compared with dogs fed the LF diet.(ABSTRACT TRUNCATED AT 250 WORDS)
Exceeding 20 000‐fold concentration of protein by the on‐line isotachophoresis concentration in poly(methyl methacrylate) microchip (2009)

In this research, a simple on-line microchip gel electrophoresis with ITP was applied for the concentration and separation of BSA and its immunoassay complex with mAb in a single cross form PMMA microchip. We investigated the ITP concentration effect in PMMA MCE using combination of leading electrolytes, terminating electrolytes and other factors. We realized an ITP-based concentration and separation of BSA and its immunoassay complexes in standard cross-channel microchip gel electrophoresis, which exceeded 2000-fold concentration of BSA immunocomplex using Tris-H3PO4 as a leading electrolyte and Tris-gamma-amino butyric acid as a terminating electrolyte. In addition, we also realized concentration of BSA sample in water, which was more than 20 000-fold and was the result of the concentration effect from combining ITP and the sample stacking techniques.