gebhart/patrepeval huggingface dataset:
Analysis and Computer Simulation of Driver/Vehicle Interaction (1987)

<div class="htmlview paragraph">This paper presents an analysis of driver/vehicle performance over a range of maneuvering conditions including accident avoidance scenarios involving vehicle limit performance handling. Driver behavior is considered in the same dynamic analysis terms as vehicle response in order to give appropriate closed-loop measures of total system maneuvering capability and handling stability. A driver control structure is developed along with closed-loop system stability constraints on model parameters over a wide range of vehicle maneuvering conditions. Example simulation runs are presented for several accident avoidance scenarios.</div>
Automatisation du métro et qualité de service (1988)

Foot Robin. Automatisation du métro et qualité de service. In: Cahier / Groupe Réseaux, n°11, 1988. pp. 36-59.
Evaluation of systematic quantification errors in velocity‐selective arterial spin labeling of the brain (2003)

Velocity-selective (VS) sequences potentially permit arterial spin labeling (ASL) perfusion imaging with labeling applied very close to the tissue. In this study the effects of cerebrospinal fluid (CSF) motion, radiofrequency (RF) field imperfections, and sequence timing parameters on the appearance and quantitative perfusion values obtained with VS-ASL were evaluated. Large artifacts related to CSF motion were observed with moderate velocity weighting, which were removed by inversion recovery preparation at the cost of increased imaging time. Imperfect refocusing and excitation pulses resulting from nonuniform RF fields produced systematic errors in the ASL subtraction images. A phase cycling scheme was introduced to eliminate these errors. Quantitative perfusion images were obtained with CSF suppression and phase cycling. Gray matter blood flow of 27.7 ml 100 g(-1) min(-1), approximately half the value reported in studies using spatially-selective ASL, was measured. Potential sources for this underestimation are discussed.
Enzyme Content and Acid Stability of Enteric-Coated Pancreatic Enzyme Products In Vitro (2005)

While assay of pancreatic enzymes reveal they were equal to their USP claims regarding their enzyme content, not all pancreatic enzyme replacements are equal in their release of lipase activity according to USP requirements. The findings maybe clinically seen with therapeutic failures of enzyme products. The FDA has recently decreed that all pancreatic enzyme products will require an approved NDA as differences in pharmaceutical quality have been identified in this product. Thus, it is considered that substitution of these products maybe questionable. Things are seldom what they seem- not all pancreatic enzyme replacements are equal. Further studies are warranted to investigate dissolution characteristics.
A Survey of Distance Metrics for Nominal Attributes (2010)

Many distance-related algorithms, such as k- nearest neighbor learning algorithms, locally weighted learn- ing algorithms etc, depend upon a good distance metric to be successful. In this kind of algorithms, a key problem is how to measure the distance between each pair of instances. In this paper, we provide a survey on distance metrics for nominal attributes, including some basic distance metrics and their improvements based on attribute weighting and attribute selection. The experimental results on the whole 36 UCI datasets published on the main web site of Weka platform validate their effectiveness.
Cytokine production by epithelial cells <sup>1</sup> (1994)

The epithelium has long been regarded as a passive barrier intended to protect the underlying tissues. Many regulatory signals, including cytokines, that control epithelial cell proliferation and differentiation and cell function during inflammation were thought to be nonepithelial-derived. Now there is a growing appreciation that epithelial cells provide some of the impetus for their own growth and differentiation, and may also regulate the function of other cells through the elaboration of certain cytokines. Moreover, because epithelial cells serve as the interface between the organism and environment, they are in a position to signal changes in the environment. It is now clear that epithelial cells respond to injury or infection with cytokine secretion. Various approaches to detecting cytokines in normal and diseased tissue have been undertaken during the past few years to establish cytokine synthesis by different epithelial. This review will examine these recent investigations in various general contexts of epithelial cell function.
Methods for Meta-Analysis in Medical Research (2000)

Major text including chapters on the following: defining outcome measures; assessing heterogeneity; using fixed effects methods and random effects models for combining study estimates; publication bias.
NQO1 inhibits proteasome-mediated degradation of HIF-1α (2016)

Overexpression of NQO1 is associated with poor prognosis in human cancers including breast, colon, cervix, lung and pancreas. Yet, the molecular mechanisms underlying the pro-tumorigenic capacities of NQO1 have not been fully elucidated. Here we show a previously undescribed function for NQO1 in stabilizing HIF-1α, a master transcription factor of oxygen homeostasis that has been implicated in the survival, proliferation and malignant progression of cancers. We demonstrate that NQO1 directly binds to the oxygen-dependent domain of HIF-1α and inhibits the proteasome-mediated degradation of HIF-1α by preventing PHDs from interacting with HIF-1α. NQO1 knockdown in human colorectal and breast cancer cell lines suppresses HIF-1 signalling and tumour growth. Consistent with this pro-tumorigenic function for NQO1, high NQO1 expression levels correlate with increased HIF-1α expression and poor colorectal cancer patient survival. These results collectively reveal a function of NQO1 in the oxygen-sensing mechanism that regulates HIF-1α stability in cancers.
Safe Driving Using Mobile Phones (2012)

As vehicle manufacturers continue to increase their emphasis on safety with advanced driver-assistance systems (ADASs), we propose a device that is not only already in abundance but portable enough as well to be one of the most effective multipurpose devices that are able to analyze and advise on safety conditions. Mobile smartphones today are equipped with numerous sensors that can help to aid in safety enhancements for drivers on the road. In this paper, we use the three-axis accelerometer of an Android-based smartphone to record and analyze various driver behaviors and external road conditions that could potentially be hazardous to the health of the driver, the neighboring public, and the automobile. Effective use of these data can educate a potentially dangerous driver on how to safely and efficiently operate a vehicle. With real-time analysis and auditory alerts of these factors, we can increase a driver's overall awareness to maximize safety.
Is Accurate Mapping of EMG Signals on Kinematics Needed for Precise Online Myoelectric Control? (2013)

In this paper, we present a systematic analysis of the relationship between the accuracy of the mapping between EMG and hand kinematics and the control performance in goal-oriented tasks of three simultaneous and proportional myoelectric control algorithms: nonnegative matrix factorization (NMF), linear regression (LR), and artificial neural networks (ANN). The purpose was to investigate the impact of the precision of the kinematics estimation by a myoelectric controller for accurately complete goal-directed tasks. Nine naïve subjects performed a series of goal-directed myoelectric control tasks using the three algorithms, and their online performance was characterized by 6 indexes. The results showed that, although the three algorithms' mapping accuracies were significantly different, their online performance was similar. Moreover, for LR and ANN, the offline performance was not correlated to any of the online performance indexes, and only a weak correlation was found with three of them for NMF . We conclude that for reliable simultaneous and proportional myoelectric control, it is not necessary to achieve high accuracy in the mapping between EMG and kinematics. Rather, good online myoelectric control is achieved by the continuous interaction and adaptation of the user with the myoelectric controller through feedback (visual in the current study). Control signals generated by EMG with rather poor association with kinematic variables can still be fully exploited by the user for precise control. This conclusion explains the possibility of accurate simultaneous and proportional control over multiple degrees of freedom when using unsupervised algorithms, such as NMF.
Down-Regulation of Murine Fibrosarcoma Transforming Growth Factor-beta1 Expression by Interleukin 7 (1995)

The regulation of endogenous tumor-derived cytokines in response to cytokine gene transfer may contribute to altered immune responses in the tumor microenvironment and thus may be an important additional parameter to assess in gene therapy.
Preliminary circulating tumour cell (CTC) analysis in phase II study of weekly cabazitaxel for "unfit" metastatic castration resistant prostate cancer patients (mCRPC) progressing after docetaxel treatment (SOGUG-CABASEM trial). (2014)

e16034 Background: Docetaxel (D) is standard first-line chemotherapy in patients (pts) with mCRPC. Cabazitaxel (C), a novel taxane developed to overcome D resistance, showed an overall survival improvement in second line CRPC in a three-weekly dose schedule. We aimed to evaluate efficacy and safety of weekly C/prednisone in
Determining the difficulty of Word Sense Disambiguation (2013)

Automatic processing of biomedical documents is made difficult by the fact that many of the terms they\ncontain are ambiguous. Word Sense Disambiguation (WSD) systems attempt to resolve these ambiguities\nand identify the correct meaning. However, the published literature on WSD systems for biomedical documents\nreport considerable differences in performance for different terms. The development of WSD systems\nis often expensive with respect to acquiring the necessary training data. It would therefore be useful\nto be able to predict in advance which terms WSD systems are likely to perform well or badly on.\nThis paper explores various methods for estimating the performance of WSD systems on a wide range\nof ambiguous biomedical terms (including ambiguous words/phrases and abbreviations). The methods\ninclude both supervised and unsupervised approaches. The supervised approaches make use of information\nfrom labeled training data while the unsupervised ones rely on the UMLS Metathesaurus. The\napproaches are evaluated by comparing their predictions about how difficult disambiguation will be\nfor ambiguous terms against the output of two WSD systems. We find the supervised methods are the\nbest predictors of WSD difficulty, but are limited by their dependence on labeled training data. The unsupervised\nmethods all perform well in some situations and can be applied more widely.
Designing and Validating Process-Variation-Aware Cell Libraries (2007)

Modeling process variations in cell libraries is fundamental to enabling statistical static timing analysis. Achieving it in an industrial setting has many stringent requirements. A generic model is proposed that satisfies these requirements. The results of its rigorous validation are explained
Size and myosin heavy chain profiles of rat hindlimb extensor muscle fibers after 2 weeks at 2G. (1996)

Although 2 weeks of chronic centrifugation at 2G resulted in a cessation of body growth, there was essentially no effect on the muscle masses or fiber size in either a slow or fast extensor muscle. These data suggest that periods of centrifugation may be beneficial in maintaining extensor muscle mass in an animal that is not growing at a normal rate e.g., during chronic unloading.
Multiferroic BiFeO3 thin films deposited on SrRuO3 buffer layer by rf sputtering (2007)

Sr Ru O 3 (SRO) acts as an effective buffer layer for growth of multiferroic BiFeO3 (BFO) thin films deposited on Pt∕TiO2∕SiO2∕Si substrates by radio frequency sputtering. Phase identification by using x-ray diffraction and texture studies by using atomic force microscopy show that the SRO buffer layer promotes crystallization and formation of the perovskite phase at lowered temperature. It significantly reduces the leakage current of multiferroic BFO films, giving rise to a much improved square ferroelectric hysteresis loop, in contrast to the poor loop for BFO on bare Pt∕TiO2∕SiO2∕Si substrate. A much enlarged remnant polarization (2Pr) of 144μC∕cm2 and a coercive field (Ec) of 386kV∕cm were obtained with the BFO thin film deposited on SRO∕Pt∕TiO2∕SiO2∕Si at 600°C. The BFO thin film with SRO buffer layer also shows a large nonvolatile polarization (ΔP=Psw−Pnsw) of 122μC∕cm2 at 20μs, which promises excellent performance for random access memories. Further interestingly, it exhibits little polarization fatigue up to 5×1010 switching cycles, at a relatively high voltage of 10V, although a notable degradation of polarization is shown at the low voltage of 6V, indicating weak domain pinning. The multiferroic thin film demonstrates a weak ferromagnetic loop with a saturation magnetization (Ms) of 1.92emu∕cm3 and coercivity (Hc) of 325Oe.
Corticotropin releasing hormone and the skin (2006)

Cotricotropin-releasing hormone (CRH) and related peptides are produced in skin that is dependent on species and anatomical location. Local peptide production is regulated by ultraviolet radiation (UVR), glucocorticoids and phase of the hair cycle. The skin also expresses the corresponding receptors (CRH-R1 and CRH-R2), with CRH-R1 being the major receptor in humans. CRH-R1 is expressed in epidermal and dermal compartments, and CRH-R2 predominantly in dermal structures. The gene coding for CRH-R1 generates multiple isoforms through a process modulated by UVR, cyclic adenosine monophosphate (cAMP) and phorbol 12-myristate 13-acetate. The phenotypic effects of CRH in human skin cells are largely mediated by CRH-R1alpha through increases in concentrations of cAMP, inositol triphosphate (IP3), or Ca2+ with subsequent activation of protein kinases A (PKA) and C (PKC) dependent pathways. CRH also modulates the activity of nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-kappaB), activator protein 1 (AP-1) and cAMP responsive element binding protein (CREB). The cellular functions affected by CRH depend on cell type and nutritional status and include modulation of differentiation program(s), proliferation, viability and immune activity. The accumulated evidence indicates that cutaneous CRH is also a component of a local structure organized similarly to the hypothalamo-pituitary-adrenal axis.
Managing Soybean Resistance to Heterodera glycines. (1998)

Heterodera glycines is an economically important pest of soybean in the United States. The steps necessary to manage this nematode are to sample for inoculum density, identify the race present, and then select appropriate control measures. Planting resistant cultivars is the most widely used management practice, and this tactic has provided enormous economic benefits. However, the nematode has adapted to each source of resistance deployed. The time required for the nematode to adapt to resistant cultivars is lengthened by including nonhost crops and susceptible cultivars in rotations with resistant cultivars. Searching for new sources of resistance and developing more techniques to prolong the effectiveness of resistance genes are necessary to maintain profitability for soybean producers.
Four Machine Learning Algorithms for Biometrics Fusion: A Comparative Study (2012)

We examine the efficiency of four machine learning algorithms for the fusion of several biometrics modalities to create a multimodal biometrics security system. The algorithms examined are Gaussian Mixture Models (GMMs), Artificial Neural Networks (ANNs), Fuzzy Expert Systems (FESs), and Support Vector Machines (SVMs). The fusion of biometrics leads to security systems that exhibit higher recognition rates and lower false alarms compared to unimodal biometric security systems. Supervised learning was carried out using a number of patterns from a well-known benchmark biometrics database, and the validation/testing took place with patterns from the same database which were not included in the training dataset. The comparison of the algorithms reveals that the biometrics fusion system is superior to the original unimodal systems and also other fusion schemes found in the literature.
Phase composition and magnetic characteristics of inert gas-atomized RE-Fe-B-based powders (1995)

Microstructure, phase constitution and temperature-dependent magnetic properties are examined for two size fractions of as-quenched RE-Nd-B-based powder produced by inert gas atomization for possible use as isotropic bonded magnet precursors. The atomized powders consist of the phase (Nd,Dy)/sub 2/Fe/sub 14/B with minute amounts of RE/sub 2/O/sub 3/ and /spl gamma/-Fe/sub 2/O/sub 3/. Evidence of compositional segregation with particle size is seen. Room-temperature magnetic properties are H/sub ci/=12 kOe and B/sub R/=5.4 kG for the 10-20 /spl mu/m portion, H/sub ci/=1.8 kOe and B/sub R/=3 kG for the 100-150 /spl mu/m portion.
Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells (2017)

Human pluripotent stem cells (hPSCs) are widely used to study cardiovascular cell differentiation and function. Here, we induced differentiation of hPSCs (both embryonic and induced) to proepicardial/epicardial progenitor cells that cover the heart during development. Addition of retinoic acid (RA) and bone morphogenetic protein 4 (BMP4) promoted expression of the mesodermal marker PDGFRα, upregulated characteristic (pro)epicardial progenitor cell genes, and downregulated transcription of myocardial genes. We confirmed the (pro)epicardial-like properties of these cells using in vitro co-culture assays and in ovo grafting of hPSC-epicardial cells into chick embryos. Our data show that RA + BMP4-treated hPSCs differentiate into (pro)epicardial-like cells displaying functional properties (adhesion and spreading over the myocardium) of their in vivo counterpart. The results extend evidence that hPSCs are an excellent model to study (pro)epicardial differentiation into cardiovascular cells in human development and evaluate their potential for cardiac regeneration.
A randomised, double-blind, placebo-controlled trial of L-carnitine in suspected acute myocardial infarction (1996)

In a randomised, double-blind placebo-controlled trial, the effects of the administration of oral L-carnitine (2 g/day) for 28 days were compared in the management of 51 (carnitine group) and 50 (placebo group) patients with suspected acute myocardial infarction. At study entry, the extent of cardiac disease, cardiac enzymes and lipid peroxides were comparable between the groups, although both groups showed an increase in cardiac enzymes and lipid peroxides. At the end of the 28-day treatment period, the mean infarct size assessed by cardiac enzymes showed a significant reduction in the carnitine group compared to placebo. Electrocardiographic assessment of infarct size revealed that the QRS-score was significantly less in the carnitine group compared to placebo (7.4 +/- 1.2 vs 10.7 +/- 2.0), while serum aspartate transaminase and lipid peroxides showed significant reduction in the carnitine group. Lactate dehydrogenase measured on the sixth or seventh day following infarction showed a smaller rise in the carnitine group compared to placebo. Angina pectoris (17.6 vs 36.0%), New York Heart Association class III and IV heart failure plus left ventricular enlargement (23.4 vs 36.0%) and total arrhythmias (13.7 vs 28.0%) were significantly less in the carnitine group compared to placebo. Total cardiac events including cardiac deaths and nonfatal infarction were 15.6% in the carnitine group vs 26.0% in the placebo group. It is possible that L-carnitine supplementation in patients with suspected acute myocardial infarction may be protective against cardiac necrosis and complications during the first 28 days.
Some New Side-Chain Liquid Crystalline Polymers For Non Linear Optics (1987)

Two different ways have been investigated to obtain side-chain liquid crystalline polymers suitable for second harmonic generation (SHG). The aim of the first one was to obtain host nematic comb-like homopolymers having a small degree of polar association of their side chains, by using a 3-fluoro-4-cyanophenyl benzoate end group. The second way consisted in synthesizing liquid crystalline polymeric systems where a mesogenic monomer and a monomeric molecule bearing a group exhibiting a large molecular hyperpolarizability p , were copolymerized. In this paper, we report on the synthesis and the phase behaviour of these two families of polymers.
Clustering of high resolution automotive radar detections and subsequent feature extraction for classification of road users (2015)

After successful entry into the automotive market some years ago radar sensor technology conquers more and more complex fields of automotive applications like Lane Change Assist or Automatic Emergency Braking systems. Future sensor generations will be challenged by constantly demanding resolution requirements not only requested by consumer rating organizations, but also by very demanding needs to realize automated driving tasks. Facing these novel challenges results in perpetual increasing of resolution requirements to guarantee highly detailed and accurate information of the surrounding area of the vehicle. Due to the high resolution operation mode a plenitude of scattering points reflected by each physical object will flood the detection list. This paper copes with the clustering of all these reflections into appropriate groups in order to exploit the advantages of multidimensional object size estimation and object classification.
Context thesaurus for the extraction of metadata from medical research papers (2004)

Much of the academic literature available on the Web has never been adequately catalogued. Consequently, even using large-scale search engines, much of it remains inaccessible to researchers as indexing on this scale lacks the necessary detail to cope with discipline dependent terminologies and ontologies. Metadata has become a popular means to provide such information within known domains. In this paper, we describe an approach to the automatic extraction of metadata from medical research papers. Medical research papers tend to have stereotypic prescribed sections, such as introduction, methods, and conclusions. The approach described uses context thesauri and the semantic structure of the documents to extract metadata based on these stereotypic sections.
Research on Database System Based on P2P Technology (2009)

P2P database system is a distributed database system, it is a combination of P2P technology and traditional database system. Introduces the concept of P2P into database system, establishes a new system of a C/S and P2P combination, and puts forward an effective solution to the traditional C/S structure of the system bottlenecks, and also discusses a number of issues related P2P database systems.
A Nonaromatic Expanded Porphyrin Derived from Anthracene—A Macrocycle which Unexpectedly Binds Anions (1992)

A chloride receptor in the solid state and an efficient fluoride carrier in solution–this describes the anion-binding properties of the diprotonated form of the novel expanded porphyrin 1. This macrocycle is prepared from the condensation of 1,8-diaminoanthracene with the corresponding doubly formyl-substituted tripyrrole. Such macrocycles may serve as models for biological anion-transport systems.