gebhart/patrepeval huggingface dataset:
Learning grasps with topographic features (2015)

We present a system for grasping unknown objects, even from piles or cluttered scenes, given a point cloud. Our method is based on the topography of a given scene and abstracts grasp-relevant structures to enable machine learning techniques for grasping tasks. We describe how Height Accumulated Features (HAF) and their extension, Symmetry Height Accumulated Features, extract grasp relevant local shapes. We investigate grasp quality using an F-score metric. We demonstrate the gain and the expressive power of HAF by comparing its trained classifier with one that resulted from training on simple height grids. An efficient way to calculate HAF is presented. We describe how the trained grasp classifier is used to explore the whole grasp space and introduce a heuristic to find the most robust grasp. We show how to use our approach to adapt the gripper opening width before grasping. In robotic experiments we demonstrate different aspects of our system on three robot platforms: a Schunk seven-degree-of-freedom arm, a PR2 and a Kuka LWR arm. We perform tasks to grasp single objects, autonomously unload a box and clear the table. Thereby we show that our approach is easily adaptable and robust with respect to different manipulators. As part of the experiments we compare our algorithm with a state-of-the-art method and show significant improvements. Concrete examples are used to illustrate the benefit of our approach compared with established grasp approaches. Finally, we show advantages of the symbiosis between our approach and object recognition.
ApoE4‐Driven Accumulation of Intraneuronal Oligomerized A<i>β</i>42 following Activation of the Amyloid Cascade <i>In Vivo</i> Is Mediated by a Gain of Function (2011)

Activating the amyloid cascade by inhibiting the Aβ-degrading enzyme neprilysin in targeted replacement mice, which express either apoE4 or apoE3, results in the specific accumulation of oligomerized Aβ42 in hippocampal CA1 neurons of the apoE4 mice. We presently investigated the extent to which the apoE4-driven accumulation of Aβ42 and the resulting mitochondrial pathology are due to either gain or loss of function. This revealed that inhibition of neprilysin for one week triggers the accumulation of Aβ42 in hippocampal CA1 neurons of the apoE4 mice but not of either the corresponding apoE3 mice or apoE-deficient mice. At 10 days, Aβ42 also accumulated in the CA1 neurons of the apoE-deficient mice but not in those of the apoE3 mice. Mitochondrial pathology, which in the apoE4 mice is an early pathological consequence following inhibition of neprilyisn, also occurs in the apoE-deficient but not in the apoE3 mice and the magnitude of this effect correlates with the levels of accumulated Aβ42 and oligomerized Aβ42 in these mice. These findings suggest that the rate-limiting step in the pathological effects of apoE4 on CA1 neurons is the accumulation of intracellular oligomerized Aβ42 which is mediated via a gain of function property of apoE4.
Development of Laser Scanner for Full Cross-Sectional Deformation Monitoring of Underground Gateroads (2017)

The deformation of underground gateroads tends to be asymmetric and complex. Traditional instrumentation fails to accurately and conveniently monitor the full cross-sectional deformation of underground gateroads. Here, a full cross-sectional laser scanner was developed, together with a visualization software package. The developed system used a polar coordinate measuring method and the full cross-sectional measurement was shown by 360° rotation of a laser sensor driven by an electrical motor. Later on, the potential impact of gateroad wall flatness, roughness, and geometrical profile, as well as coal dust environment on the performance of the developed laser scanner will be evaluated. The study shows that high-level flatness is favorable in the application of the developed full cross-sectional deformation monitoring system. For a smooth surface of gateroad, the sensor cannot receive reflected light when the incidence angle of laser beam is large, causing data loss. Conversely, the roughness surface shows its nature as the diffuse reflection light can be received by the sensor. With regards to coal dust in the measurement environment, fine particles of floating coal dust in the air can lead to the loss of measurement data to some extent, due to scattering of the laser beam.
Gallium Maltolate Treatment Eradicates<i>Pseudomonas aeruginosa</i>Infection in Thermally Injured Mice (2009)

Gallium (Ga) is a semimetallic element that has demonstrated therapeutic and diagnostic-imaging potential in a number of disease settings, including cancer and infectious diseases. Gallium's biological actions stem from its ionic radius being almost the same as that of ferric iron (Fe(3+)), whereby it can replace iron (Fe) in Fe(3+)-dependent biological systems, such as bacterial and mammalian Fe transporters and Fe(3+)-containing enzymes. Unlike Fe(3+), ionic gallium (Ga(3+)) cannot be reduced, and when incorporated, it inactivates Fe(3+)-dependent reduction and oxidation processes that are necessary for bacterial and mammalian cell proliferation. Most pathogenic bacteria require Fe for growth and function, and the availability of Fe in the host or environment can greatly enhance virulence. We examined whether gallium maltolate (GaM), a novel formulation of Ga, had antibacterial activity in a thermally injured acute infection mouse model. Dose-response studies indicated that a GaM dose as low as 25 mg/kg of body weight delivered subcutaneously was sufficient to provide 100% survival in a lethal P. aeruginosa-infected thermally injured mouse model. Mice treated with 100 mg/kg GaM had undetectable levels of Pseudomonas aeruginosa in their wounds, livers, and spleens, while the wounds of untreated mice were colonized with over 10(8) P. aeruginosa CFU/g of tissue and their livers and spleens were colonized with over 10(5) P. aeruginosa CFU/g of tissue. GaM also significantly reduced the colonization of Staphylococcus aureus and Acinetobacter baumannii in the wounds of thermally injured mice. Furthermore, GaM was also therapeutically effective in preventing preestablished P. aeruginosa infections at the site of the injury from spreading systemically. Taken together, our data suggest that GaM is potentially a novel antibacterial agent for the prevention and treatment of wound infections following thermal injury.
Analysis of Eukaryotic mRNA Structures Directing Cotranslational Incorporation of Selenocysteine (1996)

Translation of an mRNA encoding a selenoprotein requires that at least one UGA codon in the reading frame is recoded as a site for the insertion of selenocysteine. In eukaryotes, the termination codon recoding event is directed by a cis-acting signal element located in the 3' untranslated region of the gene. This 'selenocysteine insertion sequence' (SECIS) comprises conserved sequences in a region of extensive base-pairing. In order to study the structure-function relationships of the SECIS structure, we have applied a newly developed reporter gene system which allows analysis of stop codon suppression in animal cell lines. This system obviates the need for enzymatic or immunological estimation of selenoprotein synthesis, relying instead on the simple quantification of translational readthrough from the lacZ gene into the luciferase gene. The 3'-UTR of the phospholipid hydroperoxide glutathione peroxidase (PHGPx) gene was shown to contain a highly active SECIS element. Mutations in the base-paired sequences of other SECIS elements were used to analyse the significance of primary structure, secondary structure and pairing stability in the stem regions. The results demonstrate that the exact sequences of the paired nucleotides are comparatively unimportant, provided that a consensus combination of length and thermodynamic stability of the base-paired structures is maintained.
Cytochemical evidence for aerobic pathways in Mycobacterium lepraemurium. (1977)

Three enzymes of aerobic pathways (cytochrome c oxidase, peroxidase and catalase) and one key enzyme of the tricarboxylic acid cycle (succinate dehydrogenase) were investigated for their ultrastructural localization in M. lepraemurium in infected mouse liver and in cultures of M. fortuitum as a control. All four enzymes were localized in M. fortuitum. To M. lepraemurium only cytochrome c oxidase and peroxidatic activity were detected. The localization of the latter enzyme activity was different compared with M. fortuitum. Succinate dehydrogenase was not detected in M. lepraemurium but rather surprisingly was found in the membrane of the phagosomes containing the bacteria. It is concluded that M. lepraemurium can function aerobically and has either a glyoxalate pathway or is an obligate autotroph.
Automated geolocation network for use in GPS-degraded environments (2004)

Geolocation in instances where the Global Positioning System (GPS) is degraded has become an important issue in today's world. Many military and commercial applications, including unmanned systems, require an accurate location on the earth to be determined, even inside buildings or complex urban environments. This paper presents a method of complementing GPS with a mobile ad-hoc network of nodes, each of which are capable of obtaining ranges to surrounding nodes. GPS is used where available, but this method takes over when GPS is degraded. In this approach, all nodes can potentially be used by surrounding nodes to calculate position. Algorithms are being developed to select the best nodes from those available and to perform the location calculation. Some important issues are addressed, including determining the number of nodes needed to perform accurate calculations given certain error situations and understanding the way error propagates between nodes.
Novel wafer-level CSP for stacked MEMS / IC dies with hermetic sealing (2008)

Novel wafer-level chip scale package (WL-CSP) applicable to configurations involving stacking of multiple dies has been developed. Since stacked die makes high topography and it is difficult to apply conventional WL-CSP process, gold bonding wires were used for not only connecting stacked dies with one another but also for connecting from each die to CSP terminals. The WL-CSP is also applicable to microelecrromechanical system (MEMS) that requires hermetic sealing. Thin-film encapsulation for MEMS was formed by conventional back end of line (BEOL) process. Followed by die stacking and gold wire forming, chemical vapor deposition (CVD) was applied to make hermetic sealing. The WL-CSP does not require photolithography process on topography wafer. It promises a cost-effective solution for MEMS/IC dies coupled device.
Winding arms motion control method based on the dynamic model of the paper winder (2002)

This paper describes the development of a new control method for paper finishing machines, by means of which it is possible to reduce roll damage and to carry out the roll transfer movements more rapidly and accurately than with the methods presented previously. The control method includes winding arms control based on the dynamic model of the paper winder were developed and tested. Control algorithms specific to degrees of freedom are developed for the motion control of the hydraulic cylinders moving the winding arms. The functioning of the control method thus developed is verified with testing equipment containing the functions of a center winder. The verification involves the implementation of the control method in the testing equipment, test runs in a cycle corresponding to paper winding and the measurement of the accuracy of winding arm motion control achieved with this method.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
MISiCFET Chemical Sensors for Applications in Exhaust Gases and Flue Gases (2003)

A chemical gas sensor based on a silicon carbide field effect transistor with a catalytic gate metal has been under development for a number of years. The choice of silicon carbide as the semiconductor material allows the sensor to operate at high temperatures, for more than 6 months in flue gases at 300degreesC and for at least three days at 700degreesC. The chemical inertness of silicon carbide and a buried gate design makes it a suitable sensor technology for applications in corrosive environments such as exhaust gases and flue gases from boilers. The selectivity of the sensor devices is established through the choice of type and structure of the gate metal as well as the operation temperature. In this way NH3 sensors with low cross sensitivity to NOx have been demonstrated as potential sensors for control of selective catalytic reduction (SCR) of NOx by urea injection into diesel exhausts. Here we show that sensors with a porous platinum or iridium gate show different temperature ranges for NH3 detection. The hardness of the silicon carbide makes it for example more resistant to water splash at cold start of a petrol engine than existing technologies, and a sensor which can control the air to fuel ratio, before the exhaust gases are heated, has been demonstrated. Silicon carbide sensors are also tested in flue gases from boilers. Efficient regulation of the combustion in a boiler will decrease fuel consumption and reduce emissions.
Patrice Desbiens : tout a commencé ici (1995)

PATRICE DESBIENSLes pomes de Patrice Desbiens sont, en soi, diffrents les uns des autres, mais tous sont crits partir d'une mme perception des choses et des vnements.Chaque texte renferme une noirceur, une crise de folie.
Reshaping Lithium Plating/Stripping Behavior via Bifunctional Polymer Electrolyte for Room-Temperature Solid Li Metal Batteries (2016)

High-energy rechargeable Li metal batteries are hindered by dendrite growth due to the use of a liquid electrolyte. Solid polymer electrolytes, as promising candidates to solve the above issue, are expected to own high Li ion conductivity without sacrificing mechanical strength, which is still a big challenge to realize. In this study, a bifunctional solid polymer electrolyte exactly having these two merits is proposed with an interpenetrating network of poly(ether-acrylate) (ipn-PEA) and realized via photopolymerization of ion-conductive poly(ethylene oxide) and branched acrylate. The ipn-PEA electrolyte with facile processing capability integrates high mechanical strength (ca. 12 GPa) with high room-temperature ionic conductance (0.22 mS cm<sup>-1</sup>), and significantly promotes uniform Li plating/stripping. Li metal full cells assembled with ipn-PEA electrolyte and cathodes within 4.5 V vs Li<sup>+</sup>/Li operate effectively at a rate of 5 C and cycle stably at a rate of 1 C at room temperature. Because of its fabrication simplicity and compelling characteristics, the bifunctional ipn-PEA electrolyte reshapes the feasibility of room-temperature solid-state Li metal batteries.
POLARIZED LIGHT HEADLAMPS FOR VEHICLES (1973)

In polarized vehicle headlamps in which polarization takes place by means of dichroic absorbing plastic foils, these foils are subjected to marked thermal stress, so that the degree of polarization decreases after a fairly long operational period. Moeover the efficiency of these systems is low. If polarization takes place without loss by reflection from layered polarizing equipment, then the degree of polarization is inadequate because of too great a divergence of the rays leaving the reflector. By combining both methods of polarization one can obtain a polarized light headlamp which has adequate efficiency, which has little thermal stress imposed in the polarization foils, and which has the required degree of polarization. See also IRRD Abstract No. 301808. /TRRL/
Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1–PD-L1 Axis (2014)

In recent years, immune-based therapies have become an increasingly attractive treatment option for patients with cancer. Cancer immunotherapy is often used in combination with conventional chemotherapy for synergistic effects. The alkylating agent cyclophosphamide (CTX) has been included in various chemoimmunotherapy regimens because of its well-known immunostimulatory effects. Paradoxically, cyclophosphamide can also induce suppressor cells that inhibit immune responses. However, the identity and biologic relevance of these suppressor cells are poorly defined. Here we report that cyclophosphamide treatment drives the expansion of inflammatory monocytic myeloid cells (CD11b(+)Ly6C(hi)CCR2(hi)) that possess immunosuppressive activities. In mice with advanced lymphoma, adoptive transfer (AT) of tumor-specific CD4(+) T cells following cyclophosphamide treatment (CTX+CD4 AT) provoked a robust initial antitumor immune response, but also resulted in enhanced expansion of monocytic myeloid cells. These therapy-induced monocytes inhibited long-term tumor control and allowed subsequent relapse by mediating functional tolerization of antitumor CD4(+) effector cells through the PD-1-PD-L1 axis. PD-1/PD-L1 blockade after CTX+CD4 AT therapy led to persistence of CD4(+) effector cells and durable antitumor effects. Depleting proliferative monocytes by administering low-dose gemcitabine effectively prevented tumor recurrence after CTX+CD4 AT therapy. Similarly, targeting inflammatory monocytes by disrupting the CCR2 signaling pathway markedly potentiated the efficacy of cyclophosphamide-based therapy. Besides cyclophosphamide, we found that melphalan and doxorubicin can also induce monocytic myeloid suppressor cells. These findings reveal a counter-regulation mechanism elicited by certain chemotherapeutic agents and highlight the importance of overcoming this barrier to prevent late tumor relapse after chemoimmunotherapy.
Injection Molding of Rubber Compounds: Experimentation and Simulation (1991)

Abstract Results of experimental and theoretical studies of injection molding of rubber compounds have been reported. Characterizations on the rheological properties and the vulcanization kinetics of rubber compounds were carried out by means of MPT and DSC, respectively. The models were employed to fit these experimental data. An attempt has been made in extending the proposed empirical kinetic model based on DSC data to similar curing data obtained by means of the MDR technique. The heat-transfer effect due to the large sample size used in MDR measurements has been found to have a small effect on the kinetic data. Due to the different principle of state-of-cure measurements in MDR and DSC, the model parameters of curing kinetics have been found to be different in these measurements. A two-dimensional flow simulation of generalized Newtonian fluids based on both finite-difference and finite-element methods has been performed. The pressure development at various positions along the flow path during the filling stage of the molds was obtained experimentally for various injection speeds. The predicted results on pressure development during cavity filling showed qualitative agreement with the experimental data. Possible reasons for the observed discrepancy in pressure traces are: neglect of local extra pressure losses (in the juncture sections), compressibility of rubber compounds, leakage (back-flow) of material during injection, and voids formation in the injection chamber. The study on the vulcanization behavior of rubber compounds during injection molding process has also been done. The proposed empirical kinetic and induction time models were able to satisfactorily predict the cure levels of molded rubber products. At the same time, the results predicted by employing n th order kinetics were found to be unsatisfactory. The contribution of nonisothermal induction time in calculating cure levels of the molded rubber products was found to be significant. The mechanical properties and anisotropy have been investigated for two rubber compounds. It is suggested that there exists a mold temperature at which the properties and cycle times are optimal, and the filler type shows a significant effect on the tensile modulus. The rubber moldings were found to be highly anisotropic in mechanical behaviors. The anisotropy could be reduced significantly at high injection speed due to the faster stress-relaxation process.
A Closed-Loop Macro Diversity Scheme in Cooperative Multi-Point Downlink Transmission Systems (2011)

In this paper, the joint optimization issue of the cooperative precoder design is investigated for the transmission from the cooperative multi-point system to one mobile terminal. Based on the mean squared error minimization criterion, the problem is established for the cooperative precoder design. Unfortunately, this problem cannot be solved due to the block diagonal structure of the whole precoding matrix resulting from the fact that there is no data exchange among multiple base stations. In order to tackle this difficulty, the original problem is converted into an equivalent problem by stacking all of the nonzero entries in the block diagonal matrix into a long column vector. With the equivalent problem, the optimum solution is obtained in a closed-form expression by using the Lagrangian multiplier method. Numerical simulations illustrate the effectiveness of the proposed scheme in terms of bit error rate and spectral efficiency.
A Human Vision System based Flash Picture Coding Method for Video Coding (2007)

Flash light due to photographing widely appears in video sequences especially in those obtained from news interviews, conferences and sports matches. When a flash picture is encoded, the intensity changes drastically and non-uniformly so that motion estimation can not find a well-matching block in reference pictures. Accordingly, much more bits are generated than the neighboring non-flash pictures. In this paper, a novel flash picture coding method which represents a new concept of video coding is proposed. Based on human vision system (HVS) property, rather than encoding the original flash picture, it encodes an artificial flash picture which is made up of an artificial non-flash (or de-flashed) picture and some parameters for flash effect modeling. Experiments show the proposed flash picture coding method greatly reduces the coded bits of the flash picture while still provides a competitive subjective quality.
A Model for the Performance Analysis and Design of Waveguide p-i-n Photodetectors (2005)

A model to investigate the frequency response of waveguide (WG) p-i-n photodetectors (PDs) is presented. The model is based on the 2-D position-dependent distribution of carriers in the device and the results show that the contribution to the total current mainly comes from a small length of the PD measured from its input end. The effect of carrier trapping at a heterointerface has also been considered to study the frequency dependence of the photocurrent at low-bias voltages. The frequency response and bandwidth obtained from the model are in good agreement with published experimental results. A simplified and approximate relation for the fiber-to-WG coupling efficiency has also been used to calculate the overall quantum-efficiency of WGPDs. Then, the effect of WG geometry on the bandwidth-quantum efficiency product has been analyzed and some results on the optimum design of a WG p-i-n PD for maximum bandwidth-quantum efficiency product have been tabulated.