gebhart/patrepeval huggingface dataset:
The role of crystallization kinetics in the development of the structure and properties of polypropylene filaments (1993)

Abstract The processing, structure, and properties of filaments melt spun from three polypropylenes with similar rheology but substantially different crystallization kinetics were studied. The crystallization kinetics of the homopolymer was increased by the addition of a nucleating agent, whereas slower crystallization kinetics was obtained through a small amount of random copolymerization with ethylene. The relative crystallization kinetics of these three polymers was examined under quiescent conditions using differential scanning calorimetry. The technique of on‐line diameter and birefringence measurement was used to show the characteristics of the on‐line crystallization of the different resins. It was found that changing the quiescent crystallization kinetics by either the addition of a nucleating agent or through copolymerization with ethylene can produce profound effects on the structure and properties of polypropylene as‐spun filaments when they are spun under relatively low stress and low takeup velocity conditions. Higher takeup velocities and spinline stresses reduce the effect of differences in quiescent crystallization due to the influence of on‐line stress‐induced (molecular orientation‐enhanced) crystallization. © 1993 John Wiley & Sons, Inc.
Observations on the effect of raw milk quality on the keeping quality of pasteurized milk (1995)

Raw milk was stored for up to 14 d at 4 degrees C and pasteurized on days 1, 3, 4, 7, 9 and 14. Precautions were taken to eliminate post-pasteurization contamination. The pasteurized milks were stored at 4 degrees C and analysed at weekly intervals for standard plate counts (SPC), psychotrophic counts (PC) and aerobic spore counts (ASC). The initial raw milk quality was very good and the keeping quality of all the pasteurized milks tested was greater than 22 d. In some cases the milk still had acceptable SPC after 42 d storage, which shows the keeping quality that can be achieved when the process is well controlled. However, the best keeping quality resulted from milk pasteurized on the third and fourth days. Even milk pasteurized on the seventh and ninth had superior keeping quality to that pasteurized on the first day. The lactoperoxidase anti-microbial system in raw milk may be most active around days 3 and 4.
Current status of Ga<sub>2</sub>O<sub>3</sub> power devices (2016)

Abstract Gallium oxide (Ga 2 O 3 ) is an emerging wide-bandgap semiconductor for high-power, low-loss transistors and diodes by virtue of its excellent material properties and suitability for mass production. In this paper, we begin by discussing the material properties of Ga 2 O 3 that make it an attractive alternative to not only Si but also other wide-bandgap materials such as SiC and GaN. State-of-the-art Ga 2 O 3 -based devices that have been fabricated to date demonstrate the performance potential for power electronics applications.
High Efficiency Up‐Converting Single Phase Elastomers for Photon Managing Applications (2013)

Abstract Optically active materials able to up‐convert the frequency of the incident radiation can be used to enhance the performance of photovoltaic and photocatalityc cells, recovering sub‐bandgap photons not directly absorbed by the devices. Actually, sensitized up‐conversion (SUC) based on multi‐component organic systems is the most promising approach for these photon energy managing processes, being efficient also at the solar irradiance. However, applications of SUC on real devices have not been yet accomplished because its conversion yield usually drops dramatically in the solid state where the low dye mobility inhibits the diffusion controlled mechanisms ruling SUC photophysics. To overcome this limit, we prepared a single‐phase elastomer (poly‐butylacrilate) doped with proper dyes (platinum (II) octaetyl‐porphyrin and 9,10‐diphenylanthracene) to fabricate an efficient photon up‐converting material. Thanks to the residual molecular diffusion provided by the soft host, and to the quenching reduction of involved metastable electronic excited‐states in a solid environment compared to a liquid one, we obtained a record SUC yield of 17% at the solid state. SUC efficiency has been studied as function of the excitation power and sample temperature, elucidating the photophysical processes at the base of the high observed yield and assessing the guidelines for the fabrication of technologically appealing low power up‐converting materials.
Identification of cisplatin‐resistance related genes in head and neck squamous cell carcinoma (2009)

Resistance to cisplatin is a major obstacle to successful treatment of head and neck squamous cell carcinoma (HNSCC). To investigate the molecular mechanism of this resistance, we compared the gene expression profiles between the cisplatin-sensitive SCC cell lines (Sa-3, H-1 and KB) and the cisplatin-resistant cell lines established from them (Sa-3R, H-1R and KB-R) using Affymetrix U133 Plus 2.0 microarray. We identified 199 genes differentially expressed in each group. To identify important functional networks and ontologies to cisplatin resistance, the 199 genes were analyzed using the Ingenuity Pathway Analysis Tool. Fifty-one of these genes were mapped to genetic networks, and we validated the top-10 upregulated genes by real-time reverse transcriptase-polymerase chain reaction. Five novel genes, LUM, PDE3B, PDGF-C, NRG1 and PKD2, showed excellent concordance with the microarray data. In 48 patients with oral SCC (OSCC), positive immunohistochemical staining for the five genes correlated with chemoresistance to cisplatin-based combination chemotherapy. In addition, the expression of the five genes predicted the patient outcomes with chemotherapy. Furthermore, siRNA-directed suppressed expression of the five genes resulted in enhanced susceptibility to cisplatin-mediated apoptosis. These results suggested that these five novel genes have great potential for predicting the efficacy of cisplatin-based chemotherapy against OSCC. Global gene analysis of cisplatin-resistant cell lines may provide new insights into the mechanisms underlying clinical cisplatin resistance and improve the efficacy of chemotherapy for human HNSCC.
Fast triggering in high-energy physics experiments using hardware neural networks (2003)

High-energy physics experiments require high-speed triggering systems capable of performing complex pattern recognition at rates of Megahertz to Gigahertz. Neural networks implemented in hardware have been the solution of choice for certain experiments. The neural triggering problem is presented here via a detailed look at the H1 level 2 trigger at the HERA accelerator, Hamburg, Germany, followed by a section on the importance of hardware preprocessing for such systems, and finally some new architectural ideas for using field programmable gate arrays in very high-speed neural-network triggers at upcoming experiments.
Expression profiling and gene localization of rice lesion mimic mutant spl1. (2005)

The rice lesion mimic mutant spl1 shows enhanced resistance to important rice pathogens, i.e., Magnaporthe grisea (rice blast) and Xanthomonas oryzae pv. oryzae (bacterial blight). To study the broad spectrum resistance exhibited by this mutant, we examined changes in gene expression and initiated work to identify the gene responsible for the phenotype. Many lesion mimic mutants, which have been discovered in plant species including Arabidopsis thaliana, Zea mays, Hordeum vulgare and Triticum sp., show enhanced resistance to pathogen invasion.
Conversion of furfuryl alcohol into 2-methylfuran at room temperature using Pd/TiO<sub>2</sub> catalyst (2014)

The selective hydrogenation of furfuryl alcohol into 2-methylfuran was investigated at room temperature using palladium supported catalysts.
Mutational Analysis of Structural Features of Rat Hormone-Sensitive Lipase (1998)

Hormone-sensitive lipase (HSL) is a cytosolic neutral lipase that hydrolyzes intracellular stores of triacylglycerols and cholesteryl esters. HSL activity is regulated via phosphorylation-dephosphorylation, with cyclic AMP-dependent protein kinase increasing activity following phosphorylation of a single serine and Ca2+/calmodulin-dependent protein kinase II phosphorylating another serine at a basal site. The current studies used site-directed mutagenesis to show that Ser-563 of rat HSL is phosphorylated by cyclic AMP-dependent protein kinase and that Ser-565 is phosphorylated by Ca2+/calmodulin-dependent protein kinase II. Mutation of Ser-563-->Ala eliminated HSL hydrolytic activity against cholesteryl ester, triacylglycerol, and diacylglycerol substrates to the same extent as mutation of Ser-423-->Ala, the presumed catalytic site. Mutation of Ser-565-->Ala modestly decreased HSL activity. In contrast, mutation of Ser-563-->Asp preserved HSL hydrolytic activity and even increased activity 20% above the control wild-type enzyme. Molecular modeling of the catalytic pocket of HSL suggested the involvement of Val-710. Mutation of Val-710-->Ala resulted in an 85% loss of HSL hydrolytic activity. The results of these studies illustrate the importance of the presence of a hydroxyl group or negative charge at residue 563, either for proper conformation of rat HSL or for proper stabilization of substrate to allow maintenance of hydrolytic activity, as well as the importance of the involvement of additional amino acids in the catalytic pocket of the enzyme.
A message-oriented middleware for sensor networks (2004)

The miniaturization of hardware components has lead to the development of Wireless Sensor Networks (WSN) and networked-applications over them. Meanwhile, middleware systems have also been proposed in order to both facilitating the development of these applications and providing common application services. The development of middleware for sensor networks, however, places new challenges to middleware developers due to the low availability of resources and processing capacity of the sensor nodes. In this context, this paper presents a middleware for WSN named Mires. Mires incorporates characteristics of message-oriented middleware by allowing applications communicate in a publish/subscribe way. In order to illustrate the proposed middleware, we implement an aggregation middleware service for an environment-monitoring application.
Hazard monitoring for visually impaired people enabled by wireless sensor networking technology (2008)

Wireless Sensor Networks (WSNs) has been identified as a promising technology for supporting assistive environments. This article introduces PROTECT, a system that employs autonomous software objects referred to as Mobile Agents (MAs) able of locating and informing visually impaired persons for potential risks. PROTECT utilizes a 3-tier architecture where the first tier comprises a Base Station (BS), the second tier mobile sinks (carried by blinds on their sticks) and the third tier stationary sensor nodes. This WSN is deployed in an urban environment. In the event of an alarm issued by a sensor node, the BS launches a number of MAs supplied with a near-optimal itineraries that visit the nodes in the alarm's surrounding area and notify visually impaired people for potential hazards in their proximity. In the event of communication problems (e.g. failure of some sensor nodes) PROTECT modifies the itineraries of the MAs to bypass the problematic areas avoiding disruption of the data collection process from working sensors. Simulation results confirm the high effectiveness of our proposed scheme in WSNs used in assistive environments and its performance gain over alternative approaches in data fusion tasks.
Systematic evaluation of an atomic clock at 2 × 10−18 total uncertainty (2015)

The pursuit of better atomic clocks has advanced many research areas, providing better quantum state control, new insights in quantum science, tighter limits on fundamental constant variation and improved tests of relativity. The record for the best stability and accuracy is currently held by optical lattice clocks. Here we take an important step towards realizing the full potential of a many-particle clock with a state-of-the-art stable laser. Our (87)Sr optical lattice clock now achieves fractional stability of 2.2 × 10(-16) at 1 s. With this improved stability, we perform a new accuracy evaluation of our clock, reducing many systematic uncertainties that limited our previous measurements, such as those in the lattice ac Stark shift, the atoms' thermal environment and the atomic response to room-temperature blackbody radiation. Our combined measurements have reduced the total uncertainty of the JILA Sr clock to 2.1 × 10(-18) in fractional frequency units.
Recent developments in tempe research (1990)

Journal Article Recent developments in tempe research Get access M.J.R. Nout, M.J.R. Nout Department of Food Science, Agricultural University, Bomenweg 2,5703 HD Wageningen, The Netherlands * Corresponding author. Search for other works by this author on: Oxford Academic Google Scholar F.M. Rombouts F.M. Rombouts Department of Food Science, Agricultural University, Bomenweg 2,5703 HD Wageningen, The Netherlands Search for other works by this author on: Oxford Academic Google Scholar Journal of Applied Bacteriology, Volume 69, Issue 5, 1 November 1990, Pages 609–633, https://doi.org/10.1111/j.1365-2672.1990.tb01555.x Published: 01 November 1990 Article history Received: 14 March 1990 Published: 01 November 1990
Preventing and Controlling Hypertension in the Era of Genomic Innovation and Environmental Transformation (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Foreword: The Proposal to Split the Ninth Circuit Court of Appeals (1996)

Foreword: The Proposal to Split the Ninth Circuit Court of Appeals
Growth and Branching Mechanisms of Electrochemically Self-Organized Mesoscale Metallic Wires (2010)

Electrochemical metallization with copper has been developed for on-chip interconnection in microelectronics. Therefore, the need for a detailed understanding of copper electrodeposition on the micrometer and nanometer scale is essential. In particular, approaches for the self-organized growth of mesoscale wires have become of great interest recently. Here, we investigate the details of the deposit morphology of such mesoscale self-organized copper wires, focusing especially on the origin of the branching mechanism. The details of the morphology inform how the wires develop and why the branching occurs. It also shows that branching is not only associated with system noises but also with the electrical and concentration field and their coupling with interface growth. We demonstrate that by carefully adjusting the growth parameters branching can be avoided. In this way, highly ordered, periodic parallel arrays of metallic mesoscale wires were fabricated using this novel approach for self-organized growth by electrodeposition in ultrathin electrolyte layers. The results provide a general explanation for morphology formation during nonequilibrium electrocrystallization in thin electrolyte layers. This knowledge helps to develop processes for the controlled fabrication of micro- and nanostructured metallic patterns by electrochemistry.
Clippen und Füllen (1988)

In Kapitel 3 geht es um das Kappen von Linien und Polygonen am Bildschirm- oder Fensterrand. Weiter werden direkte und rekursive Algorithmen zum Füllen und Schraffieren von Polygongebieten vorgestellt und die Erzeugung von Mustern erklärt.
Modulation and action of the calcium-sensing receptor (2004)

The discovery and cloning of the calcium-sensing receptor (CaR) in 1993 has led to a better understanding of the regulation of calcium homoeostasis. Following activation by extracellular calcium ions, the CaR triggers a cascade of intracellular events. These events result in the release of secondary messengers, which have a number of biological effects, the most important of which is a reduction in parathyroid hormone (PTH) secretion. The way in which calcium acts on the CaR varies depending on the cell type. In the parathyroid gland cell, activation of the CaR by elevated serum levels of calcium leads to a decrease in PTH secretion. In the kidney, CaR activation is thought to have several different actions, leading to enhanced reabsorption of sodium chloride and increased calcium and magnesium excretion in the renal tubules. CaRs are also found in other tissues in the body that are not involved in calcium homoeostasis, suggesting that the CaR has actions that are not associated with calcium homoeostasis. In patients with end-stage renal disease, parathyroid gland hyperplasia is associated with downregulation of the CaR. Discovery of the CaR has allowed the development of a group of drugs called calcimimetics, which mimic or potentiate the actions of extracellular calcium on the CaR. These compounds have considerable potential for the treatment of primary and secondary hyperparathyroidism.
dc SQUID Readout Electronics With Up to 100 MHz Closed-Loop Bandwidth (2005)

High-speed readout electronics for sensors based on dc superconducting quantum interference devices (SQUIDs) are presented. The SQUID sensor involves a series array of 16dc SQUIDs and an intermediate transformer to enhance its current sensitivity. By using a highly gradiometric design and /spl les/5 /spl mu/m linewidth for the SQUID array, the device can be cooled down in fields of up to 85 /spl mu/T and be operated magnetically unshielded. A special feedback coil design minimizes the parasitic coupling between feedback and input coil. The SQUID sensor is directly connected to the room temperature electronics. A composite preamplifier is used consisting of a slow dc amplifier in parallel with a fast ac amplifier. A virtual 50 /spl Omega/ input resistance with negligible excess noise is realized by active shunting. Two types of high-speed readout electronics were developed. The first was designed for optimum dc performance, high flexibility, and user-friendliness. It is fully computer controlled. The white voltage and current noise levels are 0.3 nV//spl radic/Hz and 3 pA//spl radic/Hz, respectively, resulting in an overall system noise level of 0.4 /spl mu//spl Phi//sub 0///spl radic/Hz or a coupled energy sensitivity around 500h (/spl Phi//sub 0/ is the flux quantum and h is Planck's constant). The maximum flux-locked loop (FLL) and open-loop bandwidths are about 20 MHz and 50 MHz, respectively. The second readout electronics is an ultra-high-speed prototype which was designed for maximum speed at the expense of dc performance. A very low intrinsic signal delay of 1.7 ns and a high open-loop bandwidth of 300 MHz were measured. Using a novel FLL scheme, a very high signal bandwidth of 130 MHz was achieved with 0.8 m distance between SQUID and electronics.
Evidence for enhanced interleukin 2 (IL-2) secretion and IL-2 receptor presentation by synovial fluid lymphocytes in rheumatoid arthritis. (1986)

Synovial fluid lymphocytes (SFL) and peripheral blood lymphocytes (PBL) from patients with rheumatoid arthritis (RA) and reactive oligoarthritis were investigated for activated T cells (Ia+SIg-), IL-2 receptor bearing cells (Tac+) and IL-2 production in vivo and in vitro. In contrast to negative results with blood, the synovial fluid of the arthritic joints contains considerable amounts of IL-2 activity (median: 11.8 mu/ml), elevated proportions of Ia+SIg- activated T cells (median: 12.5%) and of IL-2 receptor bearing cells (median: 2.5%). In vitro, after stimulation with several Concanavalin A (Con A) doses, SFL develop proportions of IL-2 receptor cells comparable to PBL. Furthermore, they produce higher values of IL-2 activity than comparable PBL cultures. The proportions of Ia+SIg- activated T cells increase only moderately after Con A stimulation compared to in vivo data, indicating different activated T cell subsets in the synovial fluid (Ia+SIg-, Tac+). The findings are discussed as an expression of an acute hyperactivation of lymphocytes in an inflamed joint.
ChemInform Abstract: REACTIONS OF POLARIZED KETENE S,N‐ACETALS WITH HYDRAZINE: A FACILE GENERAL ROUTE TO 3(5)‐SUBSTITUTED AMINO‐4,5(3)‐SUBSTITUTED PYRAZOLES. PART XLV (1985)

Abstract Die Keten‐S,N‐ Acetale (I), (III) und (V) reagieren mit Hydrazin zu den Pyrazolen (II), (IV) bzw. (VI).
Role of cellular adhesions in tissue dynamics spectroscopy (2014)

Cellular adhesions play a critical role in cell behavior, and modified expression of cellular adhesion compounds has been linked to various cancers. We tested the role of cellular adhesions in drug response by studying three cellular culture models: three-dimensional tumor spheroids with well-developed cellular adhesions and extracellular matrix (ECM), dense three-dimensional cell pellets with moderate numbers of adhesions, and dilute three-dimensional cell suspensions in agarose having few adhesions. Our technique for measuring the drug response for the spheroids and cell pellets was biodynamic imaging (BDI), and for the suspensions was quasi-elastic light scattering (QELS). We tested several cytoskeletal chemotherapeutic drugs (nocodazole, cytochalasin-D, paclitaxel, and colchicine) on three cancer cell lines chosen from human colorectal adenocarcinoma (HT-29), human pancreatic carcinoma (MIA PaCa-2), and rat osteosarcoma (UMR-106) to exhibit differences in adhesion strength. Comparing tumor spheroid behavior to that of cell suspensions showed shifts in the spectral motion of the cancer tissues that match predictions based on different degrees of cell-cell contacts. The HT-29 cell line, which has the strongest adhesions in the spheroid model, exhibits anomalous behavior in some cases. These results highlight the importance of using three-dimensional tissue models in drug screening with cellular adhesions being a contributory factor in phenotypic differences between the drug responses of tissue and cells.