gebhart/patrepeval huggingface dataset:
Applications of time-frequency and time-scale representations to fault detection and classification (2003)

The authors propose the use of generalized time-frequency and time-scale representations coupled with a hierarchy of neural nets to solve the problem of the automatic detection and classification of faults in mechanical systems such as the gearboxes and transmissions onboard helicopters. With this technique, no underlying model for the events of interest is assumed. Rather the system learns to detect and classify faults by examination and fusion of features from training data which have known fault conditions. Results of processing real helicopter gearbox vibration data with seeded faults are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Developing Online Help for Windows, with Disk (1993)

From the Publisher:
Virtually every Windows application includes an online Help system. Developing Online Help for Windows is the essential guide to planning, writing, and building Windows Help. It is a valuable resource for both programmers and documentation writers who are involved in creating Windows Help systems. First, you study the design and writing aspects of creating Help. Learn how to coordinate Help with your print documentation; write Help topics and use layout and graphics effectively; and design your contents screens, search keyword list, hypertext jumps, and other forms of access to Help information. Then you advance to actually building the Help system. Learn how to code topic files; incorporate graphics; work with Help macros; make the project (HPJ) file; compile, test, and debug your Help system; manage the entire project; and adopt automated Help development tools such as Doc-To-Help and RoboHelp. This book offers practical guidance and specific techniques backed by clearly explained concepts and principles. At last those who create Windows Help systems have an essential resource - Developing Online Help for Windows.
Tailored triacylglycerols and esters (1989)

Conference Article| December 01 1989 Tailored triacylglycerols and esters ALASDAIR R. MACRAE ALASDAIR R. MACRAE 1Unilever Research, Colworth Laboratory, Bedford, MK44 1LQ, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1989) 17 (6): 1146–1148. https://doi.org/10.1042/bst0171146 Article history Received: June 05 1989 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation ALASDAIR R. MACRAE; Tailored triacylglycerols and esters. Biochem Soc Trans 1 December 1989; 17 (6): 1146–1148. doi: https://doi.org/10.1042/bst0171146 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1989 Biochemical Society1989 Article PDF first page preview Close Modal You do not currently have access to this content.
Role of oxidative stress in pathogenesis of metabolic syndrome. (2012)

The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and cardiovascular diseases, has become one of the major public health challenges worldwide. The pathogenesis of the metabolic syndrome is multiple and still poorly understood. No single factor has yet been identified as an underlying causal factor. There is a growing belief, however, that obesity, especially visceral obesity, may play an important role in the development of the syndrome. Visceral adiposity seems to be an independent predictor of insulin sensitivity, impaired glucose tolerance, dyslipidemia and elevated blood pressure. An increasing number of studies confirm that oxidative stress, chronic inflammation and angiogenesis all play important roles in the pathogenesis of MS. Chronic hyperglycemia causes oxidative stress in tissues prone to complications in patients with diabetes. Oxidative stress occurs in a cellular system when the production of free radical moieties exceeds the antioxidant capacity of that system. If cellular antioxidants do not remove free radicals, radicals attack and damage proteins, lipids, and nucleic acids. The oxidized or nitrosylated products of free radical attack have decreased biological activity, leading to loss of energy metabolism, cell signaling, transport, and other major functions. These altered products are also targeted for proteosome degradation, further decreasing cellular function. Accumulation of such injury ultimately leads a cell to die through necrotic or apoptotic mechanisms. In conclusion, a puzzle of many pieces of evidence suggests that free radical overgeneration may be considered the key in the generation of insulin resistance, diabetes, and cardiovascular disease.
Global Analysis of Mannitol 2-Dehydrogenase in Lactobacillus reuteri CRL 1101 during Mannitol Production through Enzymatic, Genetic and Proteomic Approaches (2017)

Several plants, fungi, algae, and certain bacteria produce mannitol, a polyol derived from fructose. Mannitol has multiple industrial applications in the food, pharmaceutical, and medical industries, being mainly used as a non-metabolizable sweetener in foods. Many heterofermentative lactic acid bacteria synthesize mannitol when an alternative electron acceptor such as fructose is present in the medium. In previous work, we reported the ability of Lactobacillus reuteri CRL 1101 to efficiently produce mannitol from sugarcane molasses as carbon source at constant pH of 5.0; the activity of the enzyme mannitol 2-dehydrogenase (MDH) responsible for the fructose conversion into mannitol being highest during the log cell growth phase. Here, a detailed assessment of the MDH activity and relative expression of the mdh gene during the growth of L. reuteri CRL 1101 in the presence of fructose is presented. It was observed that MDH was markedly induced by the presence of fructose. A direct correlation between the maximum MDH enzyme activity and a high level of mdh transcript expression during the log-phase of cells grown in a fructose-containing chemically defined medium was detected. Furthermore, two proteomic approaches (2DE and shotgun proteomics) applied in this study confirmed the inducible expression of MDH in L. reuteri. A global study of the effect of fructose on activity, mdh gene, and protein expressions of MDH in L. reuteri is thus for the first time presented. This work represents a deep insight into the polyol formation by a Lactobacillus strain with biotechnological potential in the nutraceutics and pharmaceutical areas.
Circulating Serum Levels of Cytokines and Angiogenic Factors in Patients with Cervical Cancer (1998)

Progression of cervical cancer is associated with excessive circulating levels of cytokines, which are known to be modulators of tumor angiogenesis. The concentrations of cytokines and growth factors were assayed using enzyme-linked immunosorbant assays in the serum of 61 women in various stages of cancer [stage 0 (n = 6), stage I (n = 15), stage II (n = 15), stage III (n = 15), and stage IV (n = 10)] and of 20 healthy control subjects. Our results indicated that b-FGF and TNF-beta levels were significantly elevated in stage I, and serum levels of TGF-beta and IL-7 were elevated in stages II-IV of invasive carcinoma. Our experimental subjects had significantly increased serum levels of IL-6, GM-CSF, and angiogenin in stages I-IV of cervical cancer, and TNF-alpha serum levels were elevated in all stages of invasive carcinoma. The serum levels of IL-8 and IL-10 were elevated only in stages II-III, and the levels of IL-2 were elevated in stages III-IV. The serum levels of IL-1 alpha and IL-1 beta remained unaltered in all stages of cancer progression. Progression of cervical cancer is associated with increased serum levels of angiogenin, IL-2, IL-6, IL-7, IL-8, IL-10, b-FGF TNF-alpha, TGF-beta, TNF-beta, and GM-CSF during different stages, all of which have the potential to be angiogenic amplifiers.
64/spl times/64 3D-MEMS switch control system with robustness to MEMS resonant frequency variation and pointing drift (2004)

We have demonstrated a 64/spl times/64 3D-MEMS optical crossconnect with a switching servo control system that is robust to mirror resonant frequency variations and pointing drift, resulting in typical switching times of less than 20 ms.
Chemistry, Design, and Structure−Activity Relationship of Cocaine Antagonists (2000)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry, Design, and Structure−Activity Relationship of Cocaine AntagonistsSatendra SinghView Author Information Department of Medicinal Chemistry and Pharmaceutics, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190 Cite this: Chem. Rev. 2000, 100, 3, 925–1024Publication Date (Web):February 23, 2000Publication History Received28 May 1999Published online23 February 2000Published inissue 1 March 2000https://doi.org/10.1021/cr9700538Copyright © 2000 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views3926Altmetric-Citations232LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (6 MB) Get e-AlertsSUBJECTS:Anions,Organic compounds,Pharmaceuticals,Screening assays,Selectivity Get e-Alerts
DEHALOGENATION OF CHLORINATED DIOXINS BY AN ANAEROBIC MICROBIAL CONSORTIUM FROM SEDIMENT (1995)

Anaerobic microorganisms enriched from Rhine River sediments are able to remove chlorine substituents from poly-chlorinated dibenzo-p-dioxines (PCDDs). A model PCDD, 1,2,3,4-tetrachlorodibenzo-p-dioxin (1,2,3,4–TeCDD) was reduc-tively dechlorinated to both 1,2,3–and l,2,4–trichlorodibenzo-/>-dioxins (1,2,3–and 1,2,4–TrCDD). These compounds were further dechlorinated to 1,3–and 2,3–dichlorodibenzo-p-dioxins and traces of 2–monochlorodibenzo-p-dioxin. This is the first report in the literature of the anaerobic microbial dechlorination of PCDDs. The same enrichment culture was previously found to deSchlorinate chlorinated benzenes (CBs) and polychlorinated biphenyls (PCBs). An anaerobic culture able to remove aryl chlorines from three classes of compounds has not been reported before. The rate at which the culture dechlorinates 1,2,3,4–TeCDD (t1/2 = 15.5 d) was between those observed for CBs and PCBs. This study shows that reductive dechlorination may have an effect on PCDDs in sediments, as has been demonstrated for CBs and PCBs. The formation of metabolites with a conserved 2,3-substitution pattern from 1,2,3,4–TeCDD indicates that dechlorination of highly chlorinated dibenzo-p-dioxins may result in metabolites that are potentially more toxic than the parent compounds.
Design and Implementation of a Menu Based OSCAR Command Line Interface (2007)

The open source cluster application resources (OSCAR) toolkit is used to build and maintain HPC clusters. The OSCAR cluster installer provides a graphical user interface (GUI) "wizard" that directs the user through the installation process. This GUI is useful for general usage, but in some instances a more basic interface is desirable. Therefore, a command line interface (CLI) has been developed for the OSCAR installer. Through the CLI, the OSCAR installer is better equipped to support scripting, which aids more advanced testing scenarios and helps in cluster replication. Additionally, the CLI is better suited for remote installations using OSCAR. While a graphical user interface simplifies installation for occasional users, frequent users and the OSCAR developers will find the CLI beneficial. For developers, the CLI will make testing easier because it may now be scripted for automated testing. Furthermore, because the CLI creates logs of user input, the user may create an exact duplicate of a previous installation, which could be used in later rebuilds or for diagnostic purposes when reporting issues to the developers. This paper provides an overview of the design and capabilities of the OSCAR CLI along with a brief discussion of possible future work.
Accuracy and precision of quantitative digital coronary arteriography: Observer‐, short‐, and medium‐term variabilities (1993)

Coronary arteriograms are increasingly acquired and stored in digital format, which allows instantaneous review of the pictorial data during the cardiac catheterization procedure. To support the angiographer in choosing the optimal sizes of the recanalization devices and studying the efficacy of the recanalization procedures, we have developed a new analytical software package (Automated Coronary Analysis = ACA) on the Philips DCI (-SX) digital cardiac imaging system. The ACA-package allows the objective and reproducible assessment of the morphologic and functional severity of coronary obstructions. Required user interaction is limited to the definition of the start and end points of the coronary segment to be analyzed. Automated contour detection is based on the use of first and second derivative functions along scanlines perpendicular to the automatically computed vessel pathline in the first iteration and perpendicular to the initial contours in the second iteration. These derivative functions have been modified based on the line spread function of the X-ray imaging chain, which is of particular importance for the accurate measurement of small vessel sizes. Phantom studies have indeed demonstrated that vessel sizes down to 0.66 mm can be measured accurately and reproducibly. Inter- and intraobserver variability studies have demonstrated a variability in the obstruction diameter of 0.11 mm and 0.10 mm, respectively, and in the percent diameter stenosis of 5.64% and 3.18%, respectively. These variability studies have been extended to short-term studies with repeated acquisition in the same angiographic views after 5 min and to medium-term studies with repeated acquisition in the initial angiographic views at the end of the catheterization procedures. With these standardized repeated acquisition and analysis procedures, the variabilities in the obstruction diameters increased to 0.19 and 0.18 mm, respectively, and remained below 6% in the percent diameter stenosis (5.61% and 5.28%, respectively). With an analysis time of approximately 15 sec on the DCI-SX, an efficient tool is now available in the catheterization laboratory for the objective and reproducible assessment of vessel dimensions and changes therein as a result of recanalization procedures.
Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment (2016)

Cytosolic NADPH-dependent reductase AKR1B10 is a member of the aldo-keto reductase (AKR) superfamily. This enzyme is normally expressed in the gastrointestinal tract. However, it is overexpressed in many solid tumors, such as hepatocarcinoma, lung cancer and breast cancer. AKR1B10 may play a role in the formation and development of carcinomas through multiple mechanisms including detoxification of cytotoxic carbonyls, modulation of retinoic acid level, and regulation of cellular fatty acid synthesis and lipid metabolism. Studies have suggested that AKR1B10 may be a useful biomarker for cancer diagnosis and a potential target for cancer treatment. Over the last decade, a number of AKR1B10 inhibitors including aldose reductase inhibitors (ARIs), endogenous substances, natural-based derivatives and synthetic compounds have been developed, which could be novel anticancer drugs. This review provides an overview on related articles and patents about AKR1B10 inhibitors, with a focus on their inhibition selectivity and mechanism of function.
Morocco, Western Sahara, Green March, 1975 (2010)

The Green March was a mass trek of 350,000 Moroccans into Western Sahara (former Spanish Sahara) on November 6, 1975 to claim the mostly desert territory from a regional insurgency and to declare control over the territory as a contiguous and connected subset of a “Greater Morocco.” The “march” allowed the Moroccan state to triumph over countries in the Western Sahara region, which was contested by the Polisario Front, an acronym for the Popular Front for the Liberation of Saguia el‐Hamra and Río de Oro (Frente Popular de Liberación de Saguía el Hamra y Río de Oro), a national liberation organization formed by Moroccan students of Sahrawi descent. While neighboring Algeria and Mauritania claimed the territory, the Green March proved decisive in consolidating a large territory of 103,000 square miles with fewer than 500,000 people composed of Sahrawi and Moroccan descendants.
The degradation of carbohydrates by alkali. Part VIII. Melibiose (1954)

The first page of this article is displayed as the abstract.
Mobile Edge Intelligence and Computing for the Internet of Vehicles (2019)

The Internet of Vehicles (IoV) is an emerging paradigm, driven by recent advancements in vehicular communications and networking. Advances in research can now provide reliable communication links between vehicles, via vehicle-to-vehicle communications, and between vehicles and roadside infrastructures, via vehicle-to-infrastructure communications. Meanwhile, the capability and intelligence of vehicles are being rapidly enhanced, and this will have the potential of supporting a plethora of new exciting applications, which will integrate fully autonomous vehicles, the Internet of Things (IoT), and the environment. These trends will bring about an era of intelligent IoV, which will heavily depend upon communications, computing, and data analytics technologies. To store and process the massive amount of data generated by intelligent IoV, onboard processing and Cloud computing will not be sufficient, due to resource/power constraints and communication overhead/latency, respectively. By deploying storage and computing resources at the wireless network edge, e.g., radio access points, the edge information system (EIS), including edge caching, edge computing, and edge AI, will play a key role in the future intelligent IoV. Such system will provide not only low-latency content delivery and computation services, but also localized data acquisition, aggregation and processing. This article surveys the latest development in EIS for intelligent IoV. Key design issues, methodologies and hardware platforms are introduced. In particular, typical use cases for intelligent vehicles are illustrated, including edge-assisted perception, mapping, and localization. In addition, various open research problems are identified.
Removal of Imidazoles from Caramel Color by Ultrafiltration (1976)

The ultrafiltration mechanism of the imidazoles from a caramel color through PM-10 and DDS-870 membrane was analyzed.It was found that some imidazoles were bound irreversibly to impermeable matter in the caramel and thus these imidazoles could not be removed by ultrafiltration.The following equations estimating the retained imidazoles concentration after various operations of ultra-filtration were obtained : C= (C0-KM/V0) (V0/V) Ri + KM/V (for single batch operation) Cn= (C0-KM/V0) (V/V0) n(1-Ri) + KM/V0 (for repeated batch operation) C= (C0-KM/V0) exp {- (1-Ri) Vp/V0} +KM/V0 (for fixed-volume operation) where C [mg/ml] is the concentration of imidazoles in sample, C0 [mg/ml] is the initial concentration of imidazoles in sample, Cn [mg/ml] is concentration of imidazoles in the sample after n operations of filtration (concentration factor V0/ V) and dilution (V0/V-fold), V [ml] is the volume of sample, V0 [ml] is the initial volume of sample, Vp [ml] is the volume of permeate, n [-] is times of batch operation, Ri [-] is the ideal rejection of imidazoles and KM [mg] is the amount of impermeable imidazoles.The amount of impermeable imidazoles through the membrane of Ri=0 could be obtained from KM=Ra· Cn · V0, where Ra [-] is the apparent rejection of imidazoles.It is expected that the equations obtained above are applicable to ultrafiltration of a solution in which a microsolute binds irreversibly to a high molecular weight solute.
Towards optimizing prostate tissue retrieval following holmium laser enucleation of the prostate (HoLEP): Assessment of two morcellators and review of literature (2015)

The Piranha morcellator was the most efficient and safe way to retrieve tissue after a transurethral enucleation of a prostate adenoma.
Living-related liver transplantation for patients with fulminant and subfulminant hepatic failure (1999)

The prognosis for patients with fulminant (FHF) or subfulminant hepatic failure (SFHF) has improved since the introduction of liver transplantation. However, the death rate of patients awaiting liver transplantation is high, possibly because of the difficulty in obtaining grafts in a timely manner, given the relative shortage of cadaveric donors. Between June 1990 and June 1999, 106 patients underwent living-related liver transplantation (LRLT) at Shinshu University Hospital. Among them, 8 patients had FHF and 6 had SFHF; these 14 patients are the subjects of this report. The graft volumes (GV) ranged from 231 mL to 625 mL, corresponding to 35% to 105% of the recipients' standard liver volume (SLV). The postoperative courses of all donors were uneventful. Following liver transplantation, all grafts functioned favorably, with normalization of serum total bilirubin within 3 to 5 days and normalization of coagulation profiles within 4 to 7 days. Thirteen of the 14 recipients are still alive. The actuarial 6-month, 1-year, and 5-year survival rates were 100%, 90%, and 90%, respectively. In the present study, when the ratio of the GV to the recipient's SLV was more than 35%, the graft was able to support the patient's metabolic demand after liver transplantation for FHF or SFHF. Because of the urgent nature of liver transplantation in this clinical condition, concerns over informed consent may be even greater than for elective LRLT. Nevertheless, the high success rate and low donor risk may justify this option for pediatric patients, as well as for a limited population of adult patients suffering from FHF or SFHF.
Dynamic Cell Size Adaptation and Intercell Interference Coordination in LTE HetNets (2013)

LTE heterogeneous networks (HetNets) are deployed in areas of high user density in order to increase the capacity in the cellular mobile network. However, they are raising two problems: fixed cell sizes and interference. In our work, we propose a technique, which is maximizing the throughput of the users while considering fairness, dynamically adapting cell sizes and reducing interferences. Moreover, we included the concept of cell selection offsets (CSOs) for the adaptation of the cell sizes and we applied protected subframes, a time domain intercell interference coordination technique in LTE advanced. In our results, we consider the system throughput and the 5-percentile UE throughput and show, that our technique outperforms the best static HetNet configurations achieving a gain up to 16.5% in terms of the fairness based system throughput and a gain up to 37.0% in the 5-percentile UE throughput.