gebhart/patrepeval huggingface dataset:
Reduction and electrochemistry of fullerene C60 in liquid ammonia (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReduction and electrochemistry of fullerene C60 in liquid ammoniaFeimeng Zhou, Christophe Jehoulet, and Allen J. BardCite this: J. Am. Chem. Soc. 1992, 114, 27, 11004–11006Publication Date (Print):December 1, 1992Publication History Published online1 May 2002Published inissue 1 December 1992https://pubs.acs.org/doi/10.1021/ja00053a072https://doi.org/10.1021/ja00053a072research-articleACS PublicationsRequest reuse permissionsArticle Views655Altmetric-Citations113LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Azetidine‐2‐carboxylic acid derivatives (1973)

Abstract An improved method for the preparation of DL ‐azetidine‐2‐carboxylic acid is reported. The reaction of thionyl chloride with azetidine‐2‐carboxylic acid in methanol gave rise to 2‐carbomethoxyazetidine hydrochloride, which upon treatment with triethylamine yielded 2‐carbomethoxyazetidine. 2‐Carbomethoxyazetidine proved to be unstable and upon standing formed azetidine‐2‐carboxylic acid anhydride. The nmr and ir spectra of 2‐carbomethoxyazetidine are discussed in terms of its conformation. The conversion of azetidine‐2‐carboxylic acid to azetidine‐2‐carboxamide is also described.
Look-ahead in dynamic programming and quantizer loops (2003)

The add-compare-select (ACS) loop operation in serial dynamic programming (DP) problems inherently limits the speed or the iteration period. The author shows that the ACS loop operation (although nonlinear) can exploit look-ahead. He uses techniques of look-ahead, decomposition, and incremental computation, and proposes fine-grain pipelined and parallel architectures for area-efficient high-speed VLSI implementation of DP problems. The word-level arithmetic implementation complexity of the architecture is proportional to the cube of the number of states of the DP problem, logarithmic in number of loop pipeline levels, linear in block size, and additive with respect to pipelining and block processing. The data-dependent nature of the quantization operation limits the opportunities to pipeline the quantizer loops. The author proposes an approach to transform the quantizer loop into an equivalent form that can exploit look-ahead. The transformed quantizer loop recursion is shown to be similar to the DP recursion, and variations of the DP processor architectures can be used for high-speed implementation of simple quantizer loops.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Editor's desktop (2008)

Information standards are the focus of this issue of the Bulletin. ASIS&T has a standing Standards Committee that tracks standards, formulates the Society's positions with regard to those of interest and promotes the development of new standards that seem desirable. In addition the committee has a duty to keep the membership informed about developments in this arena. While standards sessions are a regular feature of the ASIS&T Annual Meetings, the Bulletin also carries standards-related articles with some regularity. Occasionally special sections focus in some depth on particular developments, for example, the Dublin Core or those standards developments related to the Functional Requirements for Bibliographic Records (FRBR). This section, put together for the Standards Committee by Mark Needleman, who chaired the committee for a number of years, didn't start with a specific focus, but drew on the interests of the authors. The result is two articles on metadata registries and related topics; one on the revisions currently underway to the ISO standard for thesauri; one on the state of standards broadly related to the difficult area of electronic resource management (ERM); and a paper presenting a perspective of how standards relate to integrating and implementing highly complex systems. The papers are very informative, and I thank Mark, the authors and the current chair of the Standards Committee, Marcia Zeng, for their efforts. Our other feature article concerns search engine technology. Search engine technology is rapidly evolving and is of critical importance to information architecture (IA), among other fields. Many of our recent IA columns under the editorship of Stacy Surla have focused on its critical role. Here Paul Thompson reports for us on the 2008 Infonortics Search Engine Meeting, which provides a comprehensive view of the latest developments. In our IA Column in this issue, Michael Magoolaghan discusses not his work for Vanguard, but his volunteer efforts to help his local library integrate their virtual and physical environments. It is an unusual topic and one that will be of broad interest. Finally, on the ASIS&T side, we have the third installment of Margeaux Johnson's and Nancy Roderer's analysis of the data collected by a recent survey carried out by ASIS&T and Wiley-Blackwell to establish a bench line for the behavior and attitudes of readers and authors of JASIST (the ASIS&T journal) with respect to scholarly publishing prior to implementing the Society's new “Romeo green” access policy. This final piece covers the responses of respondents who said that they had published in open access journals. The problems of scholarly publication are also the subject of Nancy Roderer's President's Page, along with reflections on the future of the Society.
Antioxidant and Anti‐Cancer Potentials of <i>Rheum emodi</i> Rhizome Extracts (2010)

The objective of this study was to determine antioxidant and cytotoxic efficacies of methanolic and aqueous extracts of Rheum emodi Wall. ex Meissn. rhizome. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical scavenging activities, inhibitory effect on lipid peroxidation and Fe(3+) reducing antioxidant property have been used to investigate antioxidant properties of the extracts. Cytotoxicity of the extracts was tested on MDA-MB-435S and Hep3B cell lines. Both extracts displayed extensive cytotoxicity to the tested cell lines. The extracts were studied for their ability to protect pBR322 DNA from damage by UV induced photolysis of H(2)O(2). The aqueous extract, though inferior to methanolic extract in its antioxidant potential exhibited efficiency in DNA protection, while the methanolic extract failed to protect the DNA. The amount of total polyphenolics in the extracts was measured by spectrophotometric method. The methanolic extract contained higher polyphenolic contents than aqueous extract. Significant positive correlations were observed (P < .05) between results of phenolic content estimation and that of antioxidant assays. Hence, high-performance liquid chromatography analysis was performed to identify few major phenolic compounds that might be responsible for these therapeutic properties. These results indicate that rhizome of R. emodi possesses antioxidant and cytotoxic activities and therefore have therapeutic potential.
Interdomain traffic engineering with BGP (2003)

Traffic engineering is performed by means of a set of techniques that can be used to better control the flow of packets inside an IP network. We discuss the utilization of these techniques across interdomain boundaries in the global Internet. We first analyze the characteristics of interdomain traffic on the basis of measurements from three different Internet service providers and show that a small number of sources are responsible for a large fraction of the traffic. Across interdomain boundaries, traffic engineering relies on a careful tuning of the route advertisements sent via the border gateway protocol. We explain how this tuning can be used to control the flow of incoming and outgoing traffic, and identify its limitations.
Functional platelet-activating factor receptors linked to inositol lipid hydrolysis, calcium mobilization and tyrosine kinase activity in the human endometrial HEC-1B cell line (1994)

Platelet-activating factor (PAF; sn-1-O-alkyl-2-acetyl-sn-glycero-3- phosphocholine) is thought to be an important mediator of embryo-endometrial interactions in early pregnancy, and an understanding of its role in the establishment of early human pregnancy can only follow an understanding of its mechanism of action. In a human endometrial epithelial cell line, HEC-1B, the presence of mRNA encoding the platelet-activating factor receptor was demonstrated by reverse transcription-polymerase chain reaction. The presence of functional receptors was shown by inositol trisphosphate accumulation and a rise in the concentration of intracellular free calcium evoked by platelet-activating factor in myo-[2-3H]inositol-labelled and fura-2-loaded cells, respectively. Platelet-activating factor evoked rapid and concentration-dependent increases in the concentration of intracellular free calcium and inositol trisphosphate that were inhibited by the platelet-activating factor receptor antagonist WEB 2086, indicating that the responses are receptor mediated. Inositol trisphosphate accumulation evoked by platelet-activating factor was unaffected by pretreatment with pertussis toxin. Platelet-activating factor also stimulated the tyrosine phosphorylation of at least two major proteins of 80 kDa and 44 kDa; the smaller protein is an isoform of mitogen-activated protein kinase. These results show that functional platelet-activating factor receptors are located on the endometrial epithelial cell line HEC-1B and are linked to inositol lipid hydrolysis, calcium mobilization and tyrosine kinase activity.
Secretion of <i>Serratia liquefaciens</i> phospholipase from <i>Escherichia coli</i> (1993)

The Serratia liquefaciens phospholipase (PhlA) is secreted to the medium from its natural host. Here we present results which indicate that, when cloned and expressed in Escherichia coli, secretion can be mediated by a putative host-encoded pathway, expression of which is controlled by FlhD (formerly FlbB), the master regulator of the flagellar/chemotaxis regulon. In the absence of this secretion pathway, the synthesized phospholipase accumulates inside the host cell where it forms a complex with the PhlB protein. PhlB, which is encoded from the promoter distal gene of the phospholipase operon, inhibits the phospholipase activity of PhlA. Formation of this enzymatically inactive PhlA/PhlB complex is required for maintenance of cell viability.
Aligned Polythiophene Micro- and Nanotubules (2001)

Templated synthesis of polythiophene micro- and nanotubules using an alumina membrane is described here. Flexible polythiophene tubules up to 60 μm in length and aligned tubule/gold bilayer films (see Figure) with an area as large as 1.8 cm2 can be obtained. These bilayer films show broad, strong redox responses with a capacitance 30 times that of a normal polythiophene film.
Group communication (1996)

article Free AccessGroup communication Author: David Powell Directeur de Recherche CNRS at the Laboratoire d'Analyse et d'Architecture des Systémes Directeur de Recherche CNRS at the Laboratoire d'Analyse et d'Architecture des SystémesView Profile Authors Info & Claims Communications of the ACMVolume 39Issue 4April 1996 pp 50–53https://doi.org/10.1145/227210.227225Published:01 April 1996Publication History 130citation3,895DownloadsMetricsTotal Citations130Total Downloads3,895Last 12 Months1,051Last 6 weeks157 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
On the levels of alkyl and alk‐1‐enyl glycerolipids in normal and neoplastic tissues: A method of quantification (1974)

Abstract A method is described for the quantification of the constituent O ‐alkyl and O ‐alk‐1‐enyl glycerols of neutral lipids or phospholipids. The method involves chemical degradation, the preparation of derivatives, and quantification by gas chromatography using internal standards. Alk‐1‐enyl moieties are converted to alkyl substituted dioxanes in the presence of 1,1‐dimethoxyheptadecane as standard; alkyl glycerols are analyzed as isopropylidene derivatives using 1‐ O ‐heptadecyl glycerol as internal standard. The method is applied to the quantification of alkyl and alk‐1‐enyl glycerols derived from total lipids of rat heart, liver, testes, and brain and of various transplantable tumors, i.e. amelanotic melanoma, melanoma B16, sarcoma T241, and Novikoff hepatoma. The levels of alkyl glycerols range from 0.11–1.07% total lipids and those of alk‐1‐enyl glycerols from 0.49–5.03%. The data are compared to those obtained by other methods.
Energy management of aircraft electrical systems - state of the art and further directions (2012)

This review paper summarizes state-of-the-art energy management methods applied to electrical systems of large aircraft. An electrical load management based on fixed priorities of the loads is considered a conventional implementation as applied in today's aircraft systems. It can cut and reconnect loads depending on their importance. The advantages and disadvantages of such a system are presented. Further implementations are depicted that are able to eliminate certain drawbacks of such a typical load management. Most promising is the exploitation of so-called slow responding loads which can be handled like an electrical storage. The optimization potential on future energy management functions is finally discussed and conclusions are drawn.
Sharp Hot Fantasies of a Better World (2005)

Fatalism. The absence of hope. Not the prison of absolute belief but its opposite - the despair of knowing nothing can change. Fate rules, and has already decided. This moment, this flat featureless eternity, is beyond our influence.
Pirfenidone: Molecular Mechanisms and Potential Clinical Applications in Lung Disease (2020)

Pirfenidone (PFD) is a pharmacological compound with therapeutic efficacy in idiopathic pulmonary fibrosis. It has been chiefly characterized as an antifibrotic agent, although it was initially developed as an antiinflammatory compound because of its ability to diminish the accumulation of inflammatory cells and cytokines. Despite recent studies that have elucidated key mechanisms, the precise molecular activities of PFD remain incompletely understood. PFD modulates fibrogenic growth factors, thereby attenuating fibroblast proliferation, myofibroblast differentiation, collagen and fibronectin synthesis, and deposition of extracellular matrix. This effect is mediated by suppression of TGF-β1 (transforming growth factor-β1) and other growth factors. Here, we appraise the impact of PFD on TGF-β1 production and its downstream pathways. Accumulating evidence indicates that PFD also downregulates inflammatory pathways and therefore has considerable potential as a viable and innovative antiinflammatory compound. We examine the effects of PFD on inflammatory cells and the production of pro- and antiinflammatory cytokines in the lung. In this context, recent evidence that PFD can target inflammasome pathways and ensuing lung inflammation is highlighted. Finally, the antioxidant properties of PFD, such as its ability to inhibit redox reactions and regulate oxidative stress-related genes and enzymes, are detailed. In summary, this narrative review examines molecular mechanisms underpinning PFD and its recognized benefits in lung fibrosis. We highlight preclinical data that demonstrate the potential of PFD as a nonsteroidal antiinflammatory agent and outline areas for future research.
Accuracy of four intraoral scanners in oral implantology: a comparative in vitro study (2017)

Significant differences in trueness were found among different IOS; for each scanner, the trueness was higher in the PEM than in the FEM. Conversely, the IOS did not significantly differ in precision; for CS3600®, Omnicam® and TrueDefinition®, the precision was higher in the PEM than in the FEM. These findings may have important clinical implications.
Enhanced Visible Light Driven Photocatalytic Behavior of BiFeO3/Reduced Graphene Oxide Composites (2018)

BiFeO₃/Reduced Graphene Oxide (BFO/RGO) composites have been fabricated by a simple hydrothermal method. The X-ray diffraction (XRD), scanning electron microscopy (SEM), Raman, and X-ray photoelectron spectroscopy (XPS) analysis reveal that graphene oxide was reduced in hydrothermal process and BFO/RGO composites were successfully synthesized. UV-visible absorption and photoluminescence properties show that the introduction of RGO can effectively reduce the recombination of photogenerated electron and hole pairs. Compared to the pristine BFO, the photocatalytic performance of BiFeO₃ Graphene Oxide (BGO) composites is enhanced for the degradation of Methylene blue (MB) solution under visible light irradiation, and the result shows that the optimal amount of Graphene Oxide (GO) in the composites is 60 mg (BGO60). The excellent photocatalytic performance is mainly ascribed to improved light absorption, increased reactive sites, and the low recombination rate of electron-hole pairs. This work can provide more insights into designing advanced photocatalysts for wastewater treatment and environmental protection.
Dengue virus type 2 NS3 protease and NS2B-NS3 protease precursor induce apoptosis (2003)

Apoptosis was detected in Vero cell cultures expressing transfected dengue virus type 2 (DENV-2) genes. Approximately 17.5 and 51.5 % of cells expressing NS3 serine protease and NS2B-NS3(185) serine protease precursor protein [NS2B-NS3(185)(pro)] genes, respectively, were apoptotic. The percentage of apoptotic cells was significantly higher in cell cultures expressing NS2B-NS3(185)(pro). NS2B-NS3(185)(pro) was detected as NS2B-NS3(185)(pro)-EGFP fusion protein in cytoplasmic vesicular structures in the apoptotic cells. Site-directed mutagenesis which replaced His(51) with Ala within the protease catalytic triad significantly reduced the ability of the expressed NS3 and NS2B-NS3(185)(pro) to induce apoptosis. Results from the present study showed that DENV-2-encoded NS3 serine protease induces apoptosis, which is enhanced in cells expressing its precursor, NS2B-NS3(185)(pro). These findings suggest the importance of NS2B as a cofactor to NS3 protease-induced apoptosis.
Author wanted (1941)

Journal Article Author wanted Get access Charles Duffy Charles Duffy Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume 181, Issue 2, 12 July 1941, Page 28, https://doi.org/10.1093/nq/181.2.28b Published: 12 July 1941
Structural Characteristics and Removal of Visible-Fluorescence Species in Hydrodesulfurized Diesel Oil (1996)

The fluorescence color of a gas oil and its desulfurized oils was evaluated by using a fluorescence spectrophotometer. The visible-fluorescence species existing in the deeply desulfurized oil were separated by HPLC and identified by GC-MS (mass spectrometry), and their fluorescence emission spectra were examined and compared with those of representative polycyclic aromatic hydrocarbons. Anthracene, fluoranthene, and their alkyl derivatives are concluded to be major fluorescence species existing in the desulfurized oil at the concentration of about 10 ppmw. The color of oil was easily removed by their partial hydrogenation over NiMo catalyst at a relatively lower temperature of 280 °C for 10 min under a low hydrogen pressure of 2.9 MPa. The partial hydrogenation was ascertained to remove the fluorescence color of the model compounds.
Involvement of two alpha-ketoglutarate-dependent dioxygenases in enantioselective degradation of (R)- and (S)-mecoprop by Sphingomonas herbicidovorans MH (1997)

Cell extracts of Sphingomonas herbicidovorans MH grown on (R)-mecoprop contained an enzyme activity that selectively converted (R)-mecoprop to 4-chloro-2-methylphenol, whereas extracts of cells grown on (S)-mecoprop contained an enzyme activity selective for the S enantiomer. Both reactions were dependent on alpha-ketoglutarate and ferrous ions. Besides 4-chloro-2-methylphenol, pyruvate and succinate were detected as products of the reactions. Labeling experiments with (18)O2 revealed that both enzyme activities catalyzed a dioxygenation reaction. One of the oxygen atoms of pyruvate and one of the oxygen atoms of succinate were derived from molecular oxygen. Analysis of cell extracts obtained from cells grown on different substrates by sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed that growth on (R)-mecoprop and (S)-mecoprop caused the appearance of prominent protein bands at 34 and 32 kDa, respectively. Both protein bands were present when cells grew on the racemic mixture. The results demonstrate that S. herbicidovorans initiated the degradation of each enantiomer of mecoprop by a specific alpha-ketoglutarate-dependent dioxygenase. By comparing conversion rates of various phenoxy herbicides, we confirmed that the two enzyme activities were distinct from that of TfdA, which catalyzes the first step in the degradation of 2,4-dichlorophenoxyacetic acid in Ralstonia eutropha JMP134.
Lipid‐Coated Particles–A New Approach to Fix Membrane‐Bound Enzymes onto Carrier Surfaces (1989)

A new method to covalently link phosphatidylethanolamine via the headgroup at the surface of cell-size spherical polymer particles is described. Because the density of the reactive groups linked to the polymer beads is extremely high, a dense, tightly bonded lipid monolayer is formed. When a solubilized lipid is added to the suspension of monolayer-coated polymer beads, the spontaneous formation of a bilayer-like structure is observed. The upper layer of lipid can be removed by washing with detergent solution or organic solvents, ethanol or butanol, and can be replaced in a relipidation step by any other phospholipid; thus, an asymmetric lipid bilayer structure can be formed. Membrane-bound enzymes such as alanine aminopeptidase or dipeptidyl peptidase IV may be inserted with their hydrophobic anchor segments in a stable and enzymatically active form in this artificial system. Incorporation of integral membrane enzymes such as bacteriorhodopsin with membrane-spanning domains and bulky segments at both sides of the membrane succeeded only when a hydrophilic spacer of appropriate length (e.g., pentaalanine) was introduced between the carrier surface and the lipid headgroups.
Localization of alpha-fetoprotein by immunofluorescence in hyperplastic nodules during hepatocarcinogenesis induced by 2-acetylaminofluorene. (1974)

Summary A method for the localization of α-fetoprotein (α1F) in rat tissue by immunofluorescence is described. α1F has been found not only in fetal liver and in many hepatomas but also in hyperplastic liver nodules that appear during carcinogenesis induced by 2-acetylaminofluorene. However, as with hepatomas, the presence of α1F as observed by this method was variable. These findings with α1F are consistent with the hypothesis that hyperplastic liver nodules are an important preneoplastic or premalignant hepatocyte population.