gebhart/patrepeval huggingface dataset:
Low-loss LTCC cavity filters using system-on-package technology at 60 GHz (2005)

In this paper, three-dimensional (3-D) integrated cavity resonators and filters consisting of via walls are demonstrated as a system-on-package compact solution for RF front-end modules at 60 GHz using low-temperature cofired ceramic (LTCC) technology. Slot excitation with a /spl lambda/g/4 open stub has been applied and evaluated in terms of experimental performance and fabrication accuracy and simplicity. The strongly coupled cavity resonator provides an insertion loss <0.84 dB, a return loss >20.6 dB over the passband (/spl sim/0.89 GHz), and a 3-dB bandwidth of approximately 1.5% (/spl sim/0.89 GHz), as well as a simple fabrication of the feeding structure (since it does not require to drill vias to implement the feeding structure). The design has been utilized to develop a 3-D low-loss three-pole bandpass filter for 60-GHz wireless local area network narrow-band (/spl sim/1 GHz) applications. This is the first demonstration entirely authenticated by measurement data for 60-GHz 3-D LTCC cavity filters. This filter exhibits an insertion loss of 2.14 dB at the center frequency of 58.7 GHz, a rejection >16.4 dB over the passband, and a 3-dB bandwidth approximately 1.38% (/spl sim/0.9 GHz).
Determination of the Source of the <i>N</i>-Methyl Impurity in the Synthesis of Pemetrexed Disodium Heptahydrate (2005)

The synthesis of Pemetrexed Disodium Heptahydrate has consistently resulted in a very low level (ca. 0.02%) unknown impurity. To ensure long-term control, the identity and source of the impurity were desired. Isolation and characterization identified the impurity as the N-methyl derivative. The source was identified as the methyl groups on the peptide coupling agent, 2,6-Dimethoxy-1,3,5-triazine (CDMT). Further work assured the current conditions provide adequate control.
Synthesis of a Diverse Series of Phosphacoumarins with Biological Activity (2005)

[structure: see text] We have developed a general and efficient approach to a diverse series of phosphacoumarins as analogues of coumarins with various biological activities, and the inhibitory activity of the synthesized phosphacoumarins against the enzyme SHP-1, a protein tyrosine phosphatases, was tested. Some of them showed moderate to good efficiency.
Volume visualization of sparse irregular meshes (1992)

An algorithm that was designed for the data typically found in reservoir simulation and structural analysis is presented. Designed for general applicability and high efficiency, it can be used to visualize scalar volumes of irregular computational meshes. The algorithm accepts as input virtually any 3-D mesh used in computer simulations. Pictures of practical value can be drawn interactively.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Range Image Sensor Based on 10-$\mu{\hbox {m}}$ Lock-In Pixels in 0.18-$\mu$m CMOS Imaging Technology (2010)

This paper presents the design and characterization of a lock-in pixel array based on a buried channel photo-detector aimed at time-of-flight range imaging. The proposed photo-demodulator has been integrated in a 10-μm pixel pitch with a fill factor of 24%, and is capable of a maximum demodulation frequency of 50 MHz with a contrast of 29.5%. The sensor has been fabricated in a 0.18-μm CMOS imaging technology and assembled in a range camera system setup. The system provides a stream of three-dimensional images at 5-20 fps on a 3-6 m range, with a linearity error lower than 0.7% and a repeatability of 5-16 cm, while the best achievable precision is 2.7 cm at a 50-MHz modulation frequency.
Providing $10^{-16}$ Short-Term Stability of a 1.5-$\mu\hbox{m}$ Laser to Optical Clocks (2013)

We report on transferring 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-16</sup> -level fractional frequency stability of a “master laser” operated at 1.5 μm to a “slave laser” operated at 698 nm, using a femtosecond fiber comb as transfer oscillator. With the 698-nm laser, the <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> S <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> - <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> clock transition of <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">87</sup> Sr was resolved with a Fourier-limited linewidth of 1.5 Hz (before: 10 Hz). Potential noise sources contributed by the frequency comb are discussed in detail.
Rapid detection assays for multidrug resistance. (1988)

In attempts to develop simple and rapid assays for detection of multidrug resistance (MDR) doxorubicin-resistant S180 (S180DOX), colchicine-resistant CHO (CHOCOL) and cytarabine (cytosine-arabinoside)-resistant L1210 cell lines (L1210AraC) were investigated. S180DOX and CHOCOL cells express the MDR-phenotype while L1210AraC does not. Using a previously described short-term assay firstly, inhibition of incorporation of radioactive nucleic acid precursors into tumour cells after addition of doxorubicin was measured. Secondly, the accumulation of the fluorescent dye rhodamine 123 (R123) in the different cell lines were analyzed. It could be observed that the resistant S180DOX and CHOCOL cells needed significantly more time to accumulate R123 than their sensitive parental cell lines or L1210AraC cells. Therefore, both assays are adequate tools for the rapid detection of MDR.
Endoplasmic Reticulum Stress in Immunity (2014)

Immune responses occur in the midst of a variety of cellular stresses that can severely perturb endoplasmic reticulum (ER) function. The unfolded protein response is a three-pronged signaling axis dedicated to preserving ER homeostasis. In this review, we highlight many important and emerging functional roles for ER stress in immunity, focusing on how the bidirectional cross talk between immunological processes and basic cell biology leads to pleiotropic signaling outcomes and enhanced sensitivity to inflammatory stimuli. We also discuss how dysregulated ER stress responses can provoke many diseases, including autoimmunity, firmly positioning the unfolded protein response as a major therapeutic target in human disease.
Indium tin oxide films with low resistivity and low internal stress (2003)

Indium tin oxide (ITO) films prepared by dc magnetron sputtering were annealed in air, vacuum, and oxygen gas atmospheres. The electrical properties and internal stresses of these annealed ITO films were systematically investigated. It was found that, among the above postannealing treatments, oxygen gas annealing significantly reduced both the resistivity and the internal stress in ITO films at fairly low temperatures of 100–150 °C. Resistivities and internal stresses as low as 7×10−4 Ω cm and 38 MPa, respectively, were obtained by annealing in oxygen gas atmosphere at 100 °C. It was also revealed that the (111) crystal orientation becomes dominant and that whole grains grow dramatically as a result of postoxygen annealing, even at 100 °C.
The application of contrast‐enhanced ultrasound for the characterization of hepatic tumors: An assessment focusing on hepatocellular carcinoma (2018)

There are only limited applications of contrast‐enhanced ultrasound (CEUS) in Taiwan. We aimed to report our initial experience of CEUS in the diagnosis of hepatic tumors, focusing on hepatocellular carcinoma (HCC). From September 2015 to January 2017, 126 patients were recruited for CEUS using Definity at Tainan Municipal Hospital for the evaluation of hepatic tumors. Of the 126 patients with 64 pathology‐proven liver lesions, 61 were studied. The enhancement patterns of the liver nodules were evaluated according to the 2012 World Federation for Ultrasound in Medicine and Biology and European Federation of Societies for Ultrasound in Medicine and Biology (WFUMB‐EFSUMB) guidelines. The diagnostic value of CEUS was assessed using histopathological results as reference standards and was compared with those of dynamic computed tomography (CT) and magnetic resonance imaging (MRI). The sensitivity, specificity, accuracy, and positive and negative predictive values of CEUS in the HCC diagnosis were 73.6%, 90.9%, 76.6%, and 97.5% and 41.7%, respectively. In terms of diagnostic accuracy of HCC, the discordance between CEUS and dynamic CT/MRI was not statistically significant ( P = 0.76). Higher body mass index (>25 kg/m 2 ) showed a significantly negative association with the typical HCC enhancement pattern on CEUS ( P = 0.017). No adverse events related to the ultrasound contrast agent were found in the study. From researchers' initial experience, CEUS with Definity contrast agent can be safely and effectively applied in the diagnosis of HCC. Further investigations based on more cases of liver tumors are still warranted.
Image compression results using the LMS adaptive algorithm (1985)

The LMS algorithm may be used to adapt the coefficients of an adaptive prediction filter for image source encoding. Results are presented which show LMS may provide almost 2 bits per symbol reduction in transmitted bit rate compared to DPCM when distortion levels are approximately the same for both methods. Alternatively, LMS can be used in fixed bit-rate environments to decrease the reconstructed image distortion. When compared with fixed coefficient DPCM, reconstructed image distortion is reduced by as much as 6-7 dB using LMS. Last, pictorial results representative of LMS processing are presented.
Design and synthesis of homogeneous azeotropic distillations. 1. Problem formulation for a single column (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDesign and synthesis of homogeneous azeotropic distillations. 1. Problem formulation for a single columnDavid B. Van Dongen and Michael F. DohertyCite this: Ind. Eng. Chem. Fundamen. 1985, 24, 4, 454–463Publication Date (Print):November 1, 1985Publication History Published online1 May 2002Published inissue 1 November 1985https://pubs.acs.org/doi/10.1021/i100020a010https://doi.org/10.1021/i100020a010research-articleACS PublicationsRequest reuse permissionsArticle Views980Altmetric-Citations119LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Bacterial Antifibrinolysins. (1935)

The specific antihuman fibrinolysin formed or secreted by certain strains of Streptococci is presumably one of the main factors causing the rapid spread of certain streptococcus infections on or within human tissues. The effect of associated bacterial species on this aggressive chemical factor, therefore, is of practical clinical interest. To study such effects, an arbitrary dose of streptofibrinolysin was added to chloroformed broth cultures of the commoner associated microorganisms. At various times after this addition the fibrinolytic titers of the resulting mixtures were determined. Data thus obtained are recorded in Table I. From the table it is seen that there is a suggestive parallelism between the destruction of the fibrinolysin and the power of the associated microorganisms to liquefy gelatin. Clinically important exceptions to this rule are: Staph. aureus (2 strains), Cl. welchii and Cl. oedematiens-maligni, which liquefy gelatin but are without demonstrable antifibrinolytic action. The table further shows that the antifibrinolysin in certain bacterial cultures is partially or completely destroyed by heating to 60°C. for 30 minutes. All but one of the antifibrinolysins thus far tested are destroyed quantitatively by heating to 100°C. for 5 minutes. Heating a non-lytic fibrinolysin-antifibrinolysin mixture to 100°C. for 5 minutes will not restore its fibrinolytic function. Such a restoration would be logical if the coctostable fibrinolysin were merely bound or inhibited by the coctolabile antifibrinolysin.
Hydrazines et hydrazones hétérocycliques. IV. Synthèses de dérivés de l'hydrazine dans la série des imidazo[4,5-<i>d</i>] pyridazinones-4 (1983)

We report the syntheses of 5-alkyl or 5-aryl-3,5-dihydro[4,5-d]imidazo-4-pyridazinones (or the 1,5-dihydro derivatives) from the corresponding diaminopyridazinones. The methylation of 5-alkyl or 5-aryl-2-mercapto-3,5 (or 1,5)-dihydro [4,5-d]imidazo-4-pyridazinones leads to mixtures of 5-alkyl or 5-aryl-1 methyl-2-methylthio-3,5 (1,5)-dihydro[4,5-d]imidazo-4-pyridazinones and 5-alkyl or 5-aryl-3-methyl-2-methylthio-3,5 (or 1,5)-dihydro[4,5-d]imidazo-4-pyridazinones whose structures have been established by the Overhauser effect. These [4,5-d]imidazo-4-pyridazinones are used for the syntheses of hydrazines and hydrozones. The mass spectra of several key intermediates are presented and discussed. [Journal translation]
Cress: Dynamic Scheduling for Resource Constrained Jobs (2014)

Applications on cloud data centers are becoming more complex and various, which makes it necessary to build a flexible and constraint-aware scheduling mechanism. On one hand, dynamic resource allocation according to workloads can achieve higher utilization to the whole system. On the other hand, workload-aware scheduling for special resource can improve the performance of those individual applications. However, it is a challenge to trade off the two goals above, especially for those cloud data centers where an amount of resident services with fluctuating workloads and constraints are running. In this paper, we propose a dynamic scheduling mechanism for resource-constrained jobs. First, a dynamic description language is introduced to describe the multi-dimensional requirements for resource-constrained jobs. Second, a workload-aware resource scheduling algorithm and a conversion method between soft and hard constraints are employed to dynamically adapt to fluctuating workload. Finally, we designed a job scheduler, called Cress, which can dynamically schedule jobs by groups under the hard and soft constraints. The experimental results present that Cress can effectively manage a mixed workload with minimal operation cost and optimal performance.
Identification, Characterization, and Intracellular Processing of ADAM-TS12, a Novel Human Disintegrin with a Complex Structural Organization Involving Multiple Thrombospondin-1 Repeats (2001)

We have identified and cloned a human fetal lung cDNA encoding a new protein of the ADAM-TS family (a disintegrin and metalloproteinase domain, with thrombospondin type-1 modules) that has been called ADAM-TS12. This protein exhibits a domain organization similar to the remaining family members including a propeptide and metalloproteinase-like, disintegrin-like, and cysteine-rich domains. However, the number and organization of the TS repeats is unique with respect to other human ADAM-TSs. A total of eight TS-1 repeats arranged in three groups are present in this novel ADAM-TS. Analysis of intracellular processing of ADAM-TS12 revealed that it is synthesized as a precursor molecule that is first activated by cleavage of the prodomain in a furin-mediated process and subsequently processed into two fragments of different size: a 120-kDa N-terminal proteolytically active fragment containing the metalloproteinase and disintegrin domains, and a 83-kDa C-terminal fragment containing most of the TS-1 repeats. Somatic cell hybrid and radiation hybrid mapping experiments showed that the human ADAM-TS12 gene maps to 5q35, a location that differs from all ADAM genes mapped to date. Northern blot analysis of RNAs from human adult and fetal tissues demonstrated that ADAM-TS12 transcripts are only detected at significant levels in fetal lung but not in any other analyzed tissues. In addition, ADAM-TS12 transcripts were detected in gastric carcinomas and in tumor cell lines from diverse sources, being induced by transforming growth factor-beta in KMST human fibroblasts. These data suggest that ADAM-TS12 may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
Histamine H<sub>4</sub>receptor antagonist ameliorates chronic allergic contact dermatitis induced by repeated challenge (2009)

Because chronic allergic contact dermatitis is developed by H(4) receptor stimulation, H(4) receptor antagonists might represent new candidate drugs for treating chronic allergic contact dermatitis.
High-efficiency Removal of Fine Particles Deposited on a Solid Surface. (1994)

New methods of fine particle-removal have been developed based on a high-speed air-jet. One of the newly developed methods utilized the precharging of the surface by a needle-like electrode. It was confirmed that the method was effective for the removal of particles that adhered both to the glass and copper surfaces. Also, it was revealed that an agglomeration of particles on these surfaces was induced by pre-charging; i. e. spherical agglomerated particles were formed on the glass surface, and layered agglomerations were formed on the copper surface. These agglomerations enhanced the removal through the increase in removal force by the airflow.Vibrating air-jet removal, which was another method tested, was also effective for fine particle removal. The removal efficiency was further improved by using both the pre-charging and the vibrating air-jet achieving almost 90% removal of 1μm particles.
Quasi-transverse electromagnetic modes supported by a graphene parallel-plate waveguide (2008)

A model is developed for a parallel-plate waveguide formed by graphene. The graphene is represented by an infinitesimally thin, local two-sided surface characterized by a surface conductivity obtained from the Kubo formula. Maxwell’s equations are solved for the model fields guided by the graphene layers. It is shown that despite the extreme thinness of its walls, a graphene parallel-plate waveguide can guide quasi-transverse electromagnetic modes with attenuation similar to structures composed of metals, while providing some control over propagation characteristics via the charge density or chemical potential. Given the interest in developing graphene electronics, such waveguides may be of interest in future applications.
Involving the Community in In-School Suspension (1998)

In-school suspension programs (ISS) have been incorporated into various school systems throughout the nation since the mid-seventies (Cuttle, 1975; Hockman & Worner, 1987; Patterson, 1985; Raebeck, 1993). The basic premise of the ISS—that students stay in school and continue to learn while suspended—makes it a popular and acceptable alternative to out-of-school suspension (Meares & Kittle, 1976). However, while studies examining the effectiveness of ISS have general ly found these programs to be successful in reducing the number of out-of-school suspensions, there have been varying degrees of success in other important areas (Knoff, 1991). For example, Short and Noblett (1985) concluded that most ISS programs were mainly punitive and lacked a sufficient academic component. Other researchers found that ISS models often stressed punishment rather than rehabilitation and remediation (Casserly, Bass, & Garrett, 1980; Collins, 1985). Responding to these reported deficiencies, school systems have begun to address the needs of these sus pended students, many of them having at-risk factors in their backgrounds, in a more holistic manner (Grice, 1986; Leatt, 1987; Prior & Tulle, 1991). Recent ISS pro grams include involvement and cooperation of all school personnel, including counselors. In addition, researchers strongly suggest that parental involvement is necessary for ISS to have the greatest chance to be effective (Knopf, 1991; Novell, 1994; Prior & Tulle, 1991). However, getting parents involved is difficult, and this crucial component of a successful ISS is often absent. A rather innovative approach to parental involvement, as well as other important components, was implemented in a junior high school ISS program in Hammond, Louisiana. Not only did parents become a part of the school's efforts to assist students with at risk backgrounds, the entire community also joined in the effort to help Hammond Junior High School (one of two junior high schools in the city) keep these students in school.
Design rationale: the argument behind the artifact (1989)

We assert that the product of user interface design should be not only the interface itself but also a rationale for why the interface is the way it is. We describe a representation for design based around a semi-formal notation which allows us explicitly to represent alternative design options and reasons for choosing among them. We illustrate the approach with examples from an analysis of scrolling mechanisms. We discuss the roles we expect such a representation to play in improving the coherence of designs and in communicating reasons for choices to others, whether designers, maintainers, collaborators or end users.
The 14-3-3 Protein GF14c Acts as a Negative Regulator of Flowering in Rice by Interacting with the Florigen Hd3a (2009)

Hd3a and FT proteins have recently been proposed to act as florigens in rice and Arabidopsis, respectively; however, the molecular mechanisms of their function remain to be determined. In this study, we identified GF14c (a 14-3-3 protein) as an Hd3a-interacting protein in a yeast two-hybrid screen. In vitro and in vivo experiments, using a combination of pull-down assays and bimolecular fluorescence complementation, confirmed the interaction between Hd3a and GF14c. Functional analysis using either GF14c overexpression or knockout transgenic rice plants indicated that this interaction plays a role in the regulation of flowering. GF14c-overexpressing plants exhibited a delay in flowering and the knockout mutants displayed early flowering relative to the wild-type plants under short-day conditions. These results suggest that GF14c acts as a negative regulator of flowering by interacting with Hd3a. Since the 14-3-3 protein has been shown to interact with FT protein in tomato and Arabidopsis, our results in rice provide important findings about FT signaling in plants.
Yellow fever virus envelope protein expressed in insect cells is capable of syncytium formation in lepidopteran cells and could be used for immunodetection of YFV in human sera (2011)

The E protein expressed by the recombinant baculovirus in insect cells is antigenically similar to the wild protein and it may be useful for different medical applications, from improved diagnosis of the disease to source of antigens for the development of a subunit vaccine.
The mtp40 gene is not present in all strains of Mycobacterium tuberculosis (1996)

A multiple PCR-based assay that targets IS6110 and the mtp40 gene was evaluated for the rapid differentiation of Mycobacterium bovis and M. tuberculosis, two of the causative agents of tuberculosis. The IS6110 target is present in both species, whereas the mtp40 gene was thought to be specific for M.tuberculosis (P. Del Portillo, L.A. Murillo, and M.E. Patarroyo, J. Clin. Microbiol. 29:2163-2168, 1991). However, the mtp-40 gene is not present in all M. tuberculosis strains and, hence, is not useful for differentiating M.tuberculosis and M.bovis.