gebhart/patrepeval huggingface dataset:
Tinea versicolor in infancy (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Atypical antipsychotics, cortical D<sub>2</sub> receptors and sensitivity to endogenous dopamine (2002)

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Endometriosis: Pathogenesis, diagnosis, therapy and association with cancer (Review) (2008)

Endometriosis is a painful reproductive and immunological disease afflicting about 7-10% of women worldwide. It is one of the most frequent benign gynaecological diseases; however, little is known about the pathogenetic processes leading to the development and maintenance of this disease and the currently available therapeutic strategies are unsatisfactory. The goal of this article is to review the most recent advancements in the pathogenesis, diagnosis and therapy of this disease. The risk for cancer among women with endometriosis will be analyzed in light of the most recent epidemiological and functional studies focused on this disease.
A Hassle-free System for Ordering Websites: twopointz3ro (Prototype) (2010)

A hassle-free system for ordering websites is an example of the modern Web 2.0 trend that has emerged in the second half of the past decade; opting for simplicity and interconnectedness. The mainstream population of the Internet is demanding easier means to establishing an online presence—in the form of a dot com website or equivalent. This project, therefore, focuses on designing and developing a simple and user-friendly system for purchasing a fully functional website that does not require technical expertise.\n\nMany service providers on the Web have failed to identify the demand to expand their awareness by tuning out the needs of the mainstream, and not realizing the fact that website ownership is no longer a phenomenon only involving computer programmers and major corporations. So in order to accommodate newcomers who desire to have an extension to their Facebook and Twitter profiles, web development services must be updated and brought to these groups by making the acquisition process as clear and easy-to-understand as possible. The core objective of this project, therefore, is to investigate the requirements of the general Internet user, and create a system that allows anyone to comfortably order a suitable website for his or her purposes, whether it be business-related or exclusively personal.\n\nThe methods used during the research phase consist of benchmarking and interviewing, whereas the development phase was governed by web development methods such as HTML, CSS, MySQL, and PHP, as well as Adobe Illustrator and Photoshop for graphic design. Benchmarks were conducted on various websites and e-commerce sites for critically evaluating their user-friendliness and for extracting knowledge on how to develop more efficient websites. One project manager was also interviewed in search of advice that would shed light on how to improve web development services.\n\nThe research provided practical insights on how to adopt a minimalist approach to web design and service by eliminating distractions that cause the customer’s attention to veer away from the main objective—the acquisition of a website. This mindset demanded that the system be optimized for its key purpose by carefully handpicking what to include and what to discard.\n\nIn conclusion, the project was a success, both in terms of fulfilling the objective of developing a user-friendly ordering system for mainstream Web users, and providing invaluable personal knowledge and experience related to web development.
Epigenetic regulation of adult neural stem cells: implications for Alzheimer’s disease (2014)

Experimental evidence has demonstrated that several aspects of adult neural stem cells (NSCs), including their quiescence, proliferation, fate specification and differentiation, are regulated by epigenetic mechanisms. These control the expression of specific sets of genes, often including those encoding for small non-coding RNAs, indicating a complex interplay between various epigenetic factors and cellular functions.Previous studies had indicated that in addition to the neuropathology in Alzheimer's disease (AD), plasticity-related changes are observed in brain areas with ongoing neurogenesis, like the hippocampus and subventricular zone. Given the role of stem cells e.g. in hippocampal functions like cognition, and given their potential for brain repair, we here review the epigenetic mechanisms relevant for NSCs and AD etiology. Understanding the molecular mechanisms involved in the epigenetic regulation of adult NSCs will advance our knowledge on the role of adult neurogenesis in degeneration and possibly regeneration in the AD brain.
Molecular biology of selenium with implications for its metabolism <sup>1</sup> (1991)

Selenium has a highly specific metabolism centered around its incorporation as selenocysteine into selenoproteins. An outline of this metabolism has emerged from recent molecular biological and biochemical studies of bacteria and animals. A unique tRNA, designated tRNA[Ser]Sec, is charged with L-serine, which is then converted through at least two steps to selenocysteine. With the aid of a unique translation factor, the selenocysteinyl-tRNA[Ser]Sec recognizes specific UGA codons in mRNA to insert selenocysteine into the primary structure of selenoproteins. Turnover of selenoproteins presumably liberates selenocysteine which is toxic in its free form. Selenocysteine beta-lyase catabolizes free selenocysteine and makes its selenium available for reuse. Proteins contain almost all the selenium in animals. Of the known selenoproteins, the glutathione peroxidases contain the most selenium. Cellular and plasma glutathione peroxidases are products of different genes but have 44% identity of amino acid sequence. There is evidence for other proteins of this family. Selenoprotein P is an unrelated protein with multiple selenocysteines in its primary structure. It contains most of the selenium in rat plasma. Studies of the regulation of cellular glutathione peroxidase by selenium have yielded conflicting results, but there is a strong suggestion that mRNA levels of the rodent liver glutathione peroxidase decrease in selenium deficiency. This could be a mechanism for directing selenium to the synthesis of other selenoproteins. Although present knowledge allows construction of an outline of selenium metabolism, several steps have not been characterized and little is known about mechanisms of its regulation.
Stereochemical assignments of the 7‐phenyl‐3‐oxabicyclo[4.1.0]heptanes (1981)

Abstract A method for making stereochemical assignments based on nmr data for the 7‐phenyl‐3‐oxabicyclo[4.1.0]‐heptanes is described.
Meta-Analysis: Respiratory Tolerance to Regular β<sub>2</sub>-Agonist Use in Patients with Asthma (2004)

Regular beta2-agonist use for at least 1 week in patients with asthma results in tolerance to the drug's bronchodilator and nonbronchodilator effects and may be associated with poorer disease control compared with placebo.
Diagnostic examination of Generation 2 lithium-ion cells and assessment ofperformance degradation mechanisms. (2005)

The Advanced Technology Development (ATD) Program is a multilaboratory effort to assist industrial developers of high-power lithium-ion batteries overcome the barriers of cost, calendar life, abuse tolerance, and low-temperature performance so that this technology may be rendered practical for use in hybrid electric vehicles (HEVs). Included in the ATD Program is a comprehensive diagnostics effort conducted by researchers at Argonne National Laboratory (ANL), Brookhaven National Laboratory (BNL), and Lawrence Berkeley National Laboratory (LBNL). The goals of this effort are to identify and characterize processes that limit lithium-ion battery performance and calendar life, and ultimately to describe the specific mechanisms that cause performance degradation. This report is a compilation of the diagnostics effort conducted since spring 2001 to characterize Generation 2 ATD cells and cell components. The report is divided into a main body and appendices. Information on the diagnostic approach, details from individual diagnostic techniques, and details on the phenomenological model used to link the diagnostic data to the loss of 18650-cell electrochemical performance are included in the appendices. The main body of the report includes an overview of the 18650-cell test data, summarizes diagnostic data and modeling information contained in the appendices, and provides an assessment of the various mechanisms that have been postulated to explain performance degradation of the 18650 cells during accelerated aging. This report is intended to serve as a ready reference on ATD Generation 2 18650-cell performance and provide information on the tools for diagnostic examination and relevance of the acquired data. A comprehensive account of our experimental procedures and resulting data may be obtained by consulting the various references listed in the text. We hope that this report will serve as a roadmap for the diagnostic analyses of other lithium-ion technologies being evaluated for HEV applications. It is our hope that the information contained in this report will lead to the development of new lithium-ion cell chemistries and designs that will meet the 15-year cell calendar-life goal established by DOE's FreedomCar and Fuel Partnership.
Student Learning Style and Asynchronous Computer-Mediated Conferencing (CMC) Interaction (2005)

Abstract This article describes a study of the relation between learning style, as measured by the Kolb Learning Style Inventory, and online communication behavior, as measured by analysis of transcripts of computer-mediated conferencing (CMC) interaction using a previously developed tool. Analysis of over fifty-nine hundred sentences, generated by forty graduate students in moderated online conferences from two different courses, showed that some theoretical predications of the Kolb learning style model were confirmed, especially for the dichotomous types Convergers and Divergers, and Assimilators and Accommodators.
Effect of a precompetition bodybuilding diet and training regimen on body composition and blood chemistry. (1998)

Substantial changes in body composition and blood chemistry suggest adequate nutrition be ensured, and caution taken to avoid excessive physiologic stresses on the body during precompetition diet and training.
NASARI: a Novel Approach to a Semantically-Aware Representation of Items (2015)

José Camacho-Collados, Mohammad Taher Pilehvar, Roberto Navigli. Proceedings of the 2015 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies. 2015.
Combination therapy for hypertensive patients: end-organ protection by combination of ARB and CCB (2012)

高血圧症の治療に関し，血圧を適切なレベルまで低下させることが第一の目標となるが，治療の最終的な目的は高血圧に合併する臓器障害を予防することにある．高血圧症患者の多くは本態性高血圧症に分類され，その原因には多様な因子が関与している．そのため1種類の薬剤では血圧がコントロールできず，複数の薬剤の併用が必要になる患者が多い．その併用を考えるうえでも，臓器保護作用を視野に入れて降圧剤を選択する必要がある．降圧剤の中でも，特に臓器保護作用が強いと考えられているのがアンジオテンシン受容体拮抗薬（ARB）とカルシウム拮抗薬（CCB）であり，その臓器保護作用に注目して検討を行った．Dahl食塩高血圧ラットは，高血圧の進行と共に臓器障害を発症し死亡するモデルである．本モデルにおいて，ARBのオルメサルタンメドキソミル（OLM）とCCBのアゼルニジピン（AZL）の血圧に影響を与えない用量を併用したところ，各々の単剤に比べ相乗的な延命作用が認められた．この延命作用は，血圧を低下させない用量でも認められ，血圧を低下させる用量では，延命効果はさらに増強した．OLMとAZLのような降圧剤併用においては，血圧低下に加え，降圧作用以外のメカニズムも臓器保護作用に大きく関与すると考えられる．降圧作用以外のメカニズムとして，抗炎症作用，抗酸化作用，抗線維化作用，抗増殖・肥大作用などが考えられ，そこには薬剤クラスに共通した作用と化合物固有な作用が関与し得る．OLMとAZLの併用により，高血圧に伴う心血管疾患の罹患率および死亡率の減少への貢献が期待できる．
X-ray Diffraction Studies on Nerve (1935)

FROM analysis by means of polarized light it has long been known that nerves possess a high degree of molecular organization. The axis cylinder is positively birefringent due to the presence of anisotropic material, the optic axis of which lies parallel to the long axis of the fiber. The myelin sheath is constructed of lipoid fluid crystals with optic axes perpendicular to the direction of the fiber and radially oriented (Schmidt, 18). The positive birefringence of the axis cylinder is due presumably to the protein neurofibrils which, though visible in fixed and stained preparations, have never been demonstrated in living medullated axons under physiological conditions (Peterfi, 16). In view of the success with which the x-ray diffraction method for fine-structure analysis has been applied to certain other fibrous animal tissues such as hair, chitin, connective tissue, etc., it is desirable that full use be made of this tool in the case of nerve, particularly since modern research on nerve energetics reveals that impulse propagation takes place with but extremely small initial energy liberation. Hill (11) has shown, for example, that the heat production immediately accompanying the propagated disturbance in frog nerve at room temperature is so low as to be near the limit of measurement. It seems obvious that any mechanism capable of propagating an electric potential wave at a velocity of 30 meters per second so efficiently must owe its properties in no small measure to the molecular organization which acts as the physical substratum for the impulse propagation. Considerable advance has already been made in this direction (Herzog and Janke, 10, Handovsky and Thiessen, 8, Handovsky, 9, and Boehm, 5). Boehm, whose work is the most extensive thus far, obtained the following results: The pattern for fresh nerve consists of a ring with meridianal sickles at 4.8 Å. and equatorial points at 17 Å. The latter points decrease with drying to 11 Å. By a comparative study of nerves with varying proportions and degrees of development of the myelin sheath, axis cylinder, and connective tissue, he concluded that the 4.8 Å. ring is produced by the radial fluid crystals of the myelin sheath, while the 17 Å. equatorial points are produced by connective tissue. Neurofibrils, according to him, either do not exist or have a side spacing greater than 25 Å. (limit of his apparatus); the axis cylinder is a tube filled with a structureless, rather viscous gel. Schmitt and Wade (19, 21, 22) found that nerve shows striking thermal shortening and reacts to solvating and desolvating agents in a manner similar to that of other fibrous tissues such as tendon. These effects were thought to be due, at least partially, to the axis cylinder. In view of the recent work on the significance of thermal shortening and swelling of fibrous tissues (see particularly Meyer, 15, and Kuentzel and Prakke, 13), this indicated a certain degree of orientation in the fresh axis cylinder.
3D seismic survey design optimization (2003)

In 3D seismic survey design, the parameter choice has to satisfy a wide variety of geophysical, operational, and cost constraints. The designer of a survey has to strike a balance between the various requirements and invariably will have to settle for some kind of compromise. Hence, this design process could also be viewed as an optimization process.
Text segmentation in mixed-mode images (2002)

Block based algorithms have found widespread use in image and video compression. However, popular algorithms such as JPEG, which are very effective in compressing continuous tone images, do not perform well with mixed-mode images which have a substantial text component. With a growing number of applications where such images occur, e.g., color facsimile, digital libraries and educational videos, there are advantages in being able to classify each block as being text or continuous tone. With such a classification, different compression parameters or even algorithms may be employed for the two kinds of data to obtain high compression with minimal loss in visual quality. In this paper we analyze and compare four methods for block classification in mixed mode images, namely variance, absolute-deviation, edge, and DCT based methods. Our evaluation of each scheme is based on the accuracy of segmentation, robustness across different types of images and sensitivity to the threshold used for segmentation. Our results show that DCT based segmentation offers the best accuracy and robustness. Another advantage of DCT is that it is compatible with standards like JPEG, MPEG and H.261.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Moving target detection via airborne HRR phased array radar (2001)

We study moving target detection in the presence of temporally and spatially correlated ground clutter for airborne high range resolution (HRR) phased array radar. We divide the HRR range profiles into large range segments to avoid the range migration problems that occur in the HRR radar data. Since each range segment contains a sequence of HRR range bins, no information is lost due to the division and hence no loss of resolution occurs. We show how to use a vector autoregressive (VAR) filtering technique to suppress the ground clutter. Then a moving target detector based on a generalized likelihood ratio test (GLRT) detection strategy is derived. The detection threshold is determined according to the desired false alarm rate, which is made possible via an asymptotic statistical analysis. After the target Doppler frequency and spatial signature vectors are estimated from the VAR-filtered data as if a target were present, a simple detection variable is computed and compared with the detection threshold to render a decision on the presence of a target. Numerical results are provided to demonstrate the performance of the proposed moving target detection algorithm.
MATIA: A Programmable 80&lt;tex&gt;$mu$&lt;/tex&gt;W/frame CMOS Block Matrix Transform Imager Architecture (2006)

In this paper, we introduce our CMOS block MAtrix Transform Imager Architecture (MATIA). This imager is capable of performing programmable matrix operations on an image. The imager architecture is both modular and programmable. The pixel used in this architecture performs matrix multiplication while maintaining a high fill factor (46%), comparable to active pixel sensors. Floating gates are used to store the arbitrary matrix coefficients on-chip. The chip operates in the subthreshold domain and thus has low power consumption (80 /spl mu/W/frame). We present data for different convolutions and block transforms that were implemented using this architecture, and also present data from baseline JPEG and motion JPEG systems which we have implemented using MATIA.
End-to-end performance characterization of sensornet multi-hop routing (2005)

This paper brings out the current state of art in multi-hop routing techniques for sensor networks, specifically for many-to-one periodic data collection. We evaluate the routing layers on a large scale Sensornet testbed of 100 nodes where the nodes are densely spaced. The evaluation was focused on trying to short list the routing layer with the best data reliability. Such an evaluation is expected to be useful to researchers building pervasive applications using TinyOS based sensors (micaa2 and mica2dot) and a multi-hop routing stack. We saw that the reliable time sync and the DSDV implementation in HSN (heterogeneous sensor network) routing stack performed the best, with percentage of successful transmissions averaging at 58.3% and 62.9% respectively. The nodes that were closer to the base station had a high success rate of 86.9% for HSN DSDV and 83% for reliable time sync.
Seeding versus natural regeneration: A comparison of vegetation change following thinning and burning in ponderosa pine (2001)

The decision whether to seed with native species follow- ing restoration treatments should be based on existing vegetation, species present in or absent from the soil seed bank, past manage- ment history, microclimate conditions and soils. We installed three permanent monitoring plots in two areas (total 18.6 ha) at Mt. Trumbull, AZ. Trees were thinned and the sites burned in 1996 and 1997. A 5 ha area was seeded with native shrub, grass and forb species; the remaining 13.6 ha were unseeded. Pretreatment spe- cies richness ranged from none to five species per plot. We recorded 13 graminoid and eight shrub species in the seeded area, and four graminoid and four shrub species in the unseeded area. The greatest increase in species richness in both seeded and unseeded plots occurred approximately 1.8 years posttreatment. Perennial native species dominated plant cover by 2.8 years, although annual native forbs dominate the soil seed bank. Perennial grasses are nearly absent from the seed bank. The seeded area had the highest diversity, but it also had twice as many nonnative species (14 versus 7 in the unseeded plots). By August 1999, maximum species rich- ness reached 51 species on the seeded plot. Of these species, 80 percent were native. Although seeding increases diversity, it may also have the long-term tradeoff of introducing new genotypes and species, both native and nonnative.
Towards Reference Architecture for Cryptocurrencies: Bitcoin Architectural Analysis (2014)

Bit coin is a new protocol with a potential to revolutionize financial system. Bit coin has a complex structure, where several interacting components build a peer-to-peer currency and a payment system without relying on any trusted third party. Bit coin is continually improved by an open source community, and various Bit coin libraries, APIs, and alternative implementations are being developed. Nevertheless, there is no up-to-date protocol specification or architecture description since the official whitepaper was published back in 2008. In this paper, we provide an up-to-date protocol specification and architectural analysis of the Bit coin system. We perform this analysis as the first step towards specification of the crypto currency reference architecture. The future reference architecture will serve as a starting architectural point for the development of new systems that leverage Bit coin protocol in different contexts and for various purposes. We also discuss whether the current architecture satisfies the system's primary purpose, i.e., Providing a pure decentralized version of the crypto currency.
The effect of low-molecular-weight species on space charge and conduction in LDPE (1997)

We have investigated the effect of low-molecular mass species on the space charge behavior such as space charge distribution and electrical conduction of LDPE (low density polyethylene). We also attempted to explain the relationship between the space charge distribution and electrical conduction. The heterocharge, conduction current and effective charge mobility decreased when the low-molecular-mass species in LDPE was removed. It was found that the decrease in conduction current was related to the decrease of heterocharge in LDPE.