gebhart/patrepeval huggingface dataset:
The BTB/POZ Domain of the <i>Arabidopsis</i> Disease Resistance Protein NPR1 Interacts with the Repression Domain of TGA2 to Negate Its Function (2009)

TGA2 and NONEXPRESSER OF PR GENES1 (NPR1) are activators of systemic acquired resistance (SAR) and of the SAR marker gene pathogenesis-related-1 (PR-1) in Arabidopsis thaliana. TGA2 is a transcriptional repressor required for basal repression of PR-1, but during SAR, TGA2 recruits NPR1 as part of an enhanceosome. Transactivation by the enhanceosome requires the NPR1 BTB/POZ domain. However, the NPR1 BTB/POZ domain does not contain an autonomous transactivation domain; thus, its molecular role within the enhanceosome remains elusive. We now show by gel filtration analyses that TGA2 binds DNA as a dimer, tetramer, or oligomer. Using in vivo plant transcription assays, we localize the repression domain of TGA2 to the N terminus and demonstrate that this domain is responsible for modulating the DNA binding activity of the oligomer both in vitro and in vivo. We confirm that the NPR1 BTB/POZ domain interacts with and negates the molecular function of the TGA2 repression domain by excluding TGA2 oligomers from cognate DNA. These data distinguish the NPR1 BTB/POZ domain from other known BTB/POZ domains and establish its molecular role in the context of the Arabidopsis PR-1 gene enhanceosome.
Neisseria meningitidis Strains Isolated from Invasive Infections in France (1999-2002): Phenotypes and Antibiotic Susceptibility Patterns (2003)

Infections due to Neisseria meningitidis are a major public health concern. In France, during 1999-2002, a total of 2167 clinical isolates of N. meningitidis from invasive infections were studied at the National Reference Center for Meningococci (Paris). Serogroup B strains were the most common (58%), followed by serogroup C strains (29%) and serogroup W135 strains (8%). Various phenotypes were observed, reflecting heterogeneity in the meningococcal population. Strains were susceptible to antibiotics currently used for treatment and chemoprophylaxis of meningococcal infections. However, the prevalence of meningococci with reduced susceptibility to penicillin is increasing. Such strains were heterogeneous and accounted for approximately 30% of isolates during this period, warranting continued surveillance of this phenomenon.
Enhancing the Effectiveness of Virtual Screening by Fusing Nearest Neighbor Lists:  A Comparison of Similarity Coefficients (2004)

This paper evaluates the effectiveness of various similarity coefficients for 2D similarity searching when multiple bioactive target structures are available. Similarity searches using several different activity classes within the MDL Drug Data Report and the Dictionary of Natural Products databases are performed using BCI 2D fingerprints. Using data fusion techniques to combine the resulting nearest neighbor lists we obtain group recall results which, in many cases, are a considerable improvement on standard average recall values obtained for individual structures. It is shown that the degree of improvement can be related to the structural diversity of the activity class that is searched for, the best results being found for the most diverse groups. The group recall of active compounds using subsets of the class is also investigated: for highly self-similar activity classes, the group recall improvement saturates well before the full activity class size is reached. A rough correlation is found between the relative improvement using the group recall and the square of the number of unique compounds available in all of the merged lists. The Tanimoto coefficient is found unambiguously to be the best coefficient to use for the recovery of active compounds using multiple targets. Furthermore, when using the Tanimoto coefficient, the "MAX" fusion rule is found to be more effective than the "SUM" rule for the combination of similarity searches from multiple targets. The use of group recall can lead to improved enrichment in database searches and virtual screening.
Gate Driver Circuit for a 15-inch AMOLED Display with Narrow Border (2021)

Top-gate thin-film transistors (TFTs) has been proposed and introduced to fabricate active-matrix organic light-emitting diode (AMOLED) displays with large size and high resolution. The electrical characteristics, uniformity and photostability of the top-gate TFTs have been studied systematically. Experimental results show that the Ion/Ioff ratio reaches 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">7</sup> , indicating good switching characteristic. Meanwhile, the threshold voltage (Vth) over the whole AMOLED display changes from -0.5V to 0.7V, demonstrating good uniformity TFT process. A novel circuit design technology for gate driver on array (GOA) circuits integrating with top-gate TFTs has been proposed. In contrast to traditional GOA circuit, each GOA stage proposed in the work can export two shift register pulses. By using this technology, narrow border in AMOLED display can be obtained. The performance and the stabilization of GOA circuit has been systematically studied. Finally, this GOA circuit is placed in a 15-inch AMOLED display to testify the function.
A Review of Recent Studies on Aqueous Binary Mixed Surfactant Systems (2008)

Recent studies on mixed surfactant systems were systematically overviewed, paying special attention to synergism observed in micellization as well as adsorbed film formation upon mixing of a few nonionic surfactants with a variety of surfactants (such as anionics including bile salts and a hybrid type surfactant, cationics including a Gemini type surfactant, different types of nonionics and a zwitterionic surfactant used as a membrane solubilizer) in addition to various combinations of anionics. Through the text, it was shown for each given binary mixed system composed of surfactants 1 and 2 how to estimate not only the composition of mixed micelles (Y(2)) equilibrated with singly dispersed surfactant species in bulk solution phase, where the mole fraction of 2 in the surfactant mixture is denoted as X(2), but also the composition of adsorbed film phase (Z(2)). Almost all combinations were discussed in terms of the respective interaction parameters, omega(R) and omega(A), in mixed micelles (3-D phase) and in mixed adsorbed film (2-D phase), respectively, surface excess concentration (Gamma), partial molecular area (PMA), minimum surface Gibbs energy (G(s)min), and such defined measures as pC(20), CMC/C(20) etc. for evaluation of synergism.
Stark broadening in radio recombination lines towards the Orion nebula. (1984)

On a etudie l'elargissement Stark des raies de recombinaison radio de l'hydrogene en observant une serie de raies adjacentes d'ordre eleve et une raie nα non elargie. Les calculs conduisent a des densites electroniques de (1±0,3).10 4 cm −3
Impact of Follow-up Testing on Survival and Health-Related Quality of Life in Breast Cancer Patients (1994)

Results of this trial support the view that a protocol of frequent laboratory tests and roentgenography after primary treatment for breast cancer does not improve survival or influence health-related quality of life. Routine use of these tests should be discouraged.
Design and Analysis of Harmonic Rejection Mixers With Programmable LO Frequency (2013)

A harmonic rejection mixer (HRM) with a programmable local oscillator (LO) frequency is presented. The design allows for the generation of multiple effective LO frequencies within a single HRM that are derived from a single primary clock frequency, without any modifications to the analog signal path. A 16-phase HRM with the proposed frequency synthesis technique is implemented in a 130-nm CMOS process. A clocking approach within a two-stage HRM is presented, which reduces HRM sensitivity to both gain and phase mismatch. The HRM synthesizes eight effective LO frequencies and shows an 11.9-dB gain, 11.2-dB DSB NF, and +5.4-dBm in-band IIP3 in the fundamental mode. Greater than 72-dB HR3, 71-dB HR5, and 67-dB HR7 is achieved over ten IC samples in this mode without calibration or harmonic filtering. Harmonic rejection greater than 61 dB for LO factors 2-6 and 54 dB for LO factor 7 is observed, when modifying the effective LO frequency. The HRM achieves S11 better than -10 dB over 50-830 MHz and has a total power consumption of 67 mW from a 1.2-V supply.
Effects of Resin Rheology on the Extrusion Foaming Characteristics of PET (1998)

Extrusion foaming by injection of inert gases (carbon dioxide, nitrogen, argon) in the polymer melt is increasingly finding applications for a wide variety of resins, competing with chemical blowing agents, volatile organic compounds or microcellular foaming. The molecular weight and molecular weight distribution of the resin affect its rheological characteristics (shear and elongational viscosity, melt elasticity, melt strength), its process characteristics and control cell size and stability of the resulting foam. In the present work, a variety of PET resins (including virgin materials, recycled and post-reactor modified) having different rheological characteristics were foamed by direct carbon dioxide injection and through the use of chemical blowing agents. Formability as related to density and cell size and distribution was evaluated and correlated with rheological characteristics of the particular resin, process conditions and type of blowing agent.
Reactivity of tertiary silanes and stannanes with an edge-bridged triruthenium carbonyl cluster complex (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactivity of tertiary silanes and stannanes with an edge-bridged triruthenium carbonyl cluster complexJavier A. Cabeza, R. Jesus Franco, Angela Llamazares, Victor Riera, Claudette Bois, and Yves JeanninCite this: Inorg. Chem. 1993, 32, 21, 4640–4642Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/ic00073a028https://doi.org/10.1021/ic00073a028research-articleACS PublicationsRequest reuse permissionsArticle Views67Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
WASSERTRANSPORT DURCH DIFFUSION IN FESTSTOFFEN, INSBESONDEREIN BAUSTOFFEN, KUNSTSTOFFEN, BESCHICHTUNGEN (1974)

NACH GRUNDLEGENDEN AUSFUEHRUNGEN UEBER DAS WASSERMOLEKUEL GEHT DER VERFASSER AUF DEN WASSERGEHALT DER FESTKOERPER EIN MIT DEN THEORIEN UEBER DIE ADSORPTION UND DIE LOESLICHKEIT. ES FOLGEN BETRACHTUNGEN UEBER DEN WASSERTRANSPORT IN FESTKOERPERN, NAEMLICH DIE SICKERSTROEMUNG, DEN ELEKTROKINETISCHEN UND KAPILLAREN WASSERTRANSPORT UND SCHLIESSLICH DIE WASSERDAMPFDIFFUSION IM TEMPERATURGLEICHGEWICHT UND IM TEMPERATURGEFAELLE. DIE WEITEREN KAPITEL BEHANDELN DIE LOESUNGSDIFFUSION, ZUNAECHST UNTER DER ANNAHME EINES KONSTANTEN DIFFUSIONSKOEFFIZIENTEN UND SCHLIESSLICH IN ALLGEMEINER FORM BEI KONZENTRATIONSABHAENGIGEM DIFFUSIONSKOEFFIZIENTEN, WODURCH SICH DIE BEKANNTEN BESONDERHEITEN DER LOESUNGSDIFFUSION ZWANGLOS ERKLAEREN LASSEN. DER ANHANG BRINGT TABELLEN UND DIAGRAMME ZUR ERLEICHTERUNG DER PRAKTISCHEN ANWENDUNG DES STOFFES. (A*).
Multiresolution analysis for meshes with appearance attributes (2005)

We present a new multiresolution analysis framework for irregular meshes with attributes based on the lifting scheme. We introduce a surface prediction operator to compute the detail coefficients for the geometry and the attributes of the model. Attribute analysis gives appearance information to complete the geometrical analysis of the model. A set of experimental results are given to show the efficiency of our framework. We present two applications to adaptive visualization and denoising.
Using finite element analysis to calculate the shapes of geometrically confined drops of liquid on patterned, self-assembled monolayers: a new method to estimate excess interfacial free energies .gamma.sv - .gamma.sl (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUsing finite element analysis to calculate the shapes of geometrically confined drops of liquid on patterned, self-assembled monolayers: a new method to estimate excess interfacial free energies .gamma.sv - .gamma.slNicholas L. Abbott, George M. Whitesides, Livia M. Racz, and Julian SzekelyCite this: J. Am. Chem. Soc. 1994, 116, 1, 290–294Publication Date (Print):January 1, 1994Publication History Published online1 May 2002Published inissue 1 January 1994https://pubs.acs.org/doi/10.1021/ja00080a033https://doi.org/10.1021/ja00080a033research-articleACS PublicationsRequest reuse permissionsArticle Views225Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Homing endonucleases catalyze double‐stranded DNA breaks and somatic transgene excision in <i>Aedes aegypti</i> (2009)

Aedes aegypti is a major vector of arthropod-borne viruses such as yellow fever virus and dengue viruses. Efforts to discern the function of genes involved in important behaviours, such as vector competence and host seeking through reverse genetics, would greatly benefit from the ability to generate targeted gene disruptions. Homing endonucleases are selfish elements which catalyze double-stranded DNA (dsDNA) breaks in a sequence-specific manner. In this report we demonstrate that the homing endonucleases I-PpoI, I-SceI, I-CreI and I-AniI are all able to induce dsDNA breaks in adult female Ae. aegypti chromosomes as well as catalyze the somatic excision of a transgene. These experiments provide evidence that homing endonucleases can be used to manipulate the genome of this important disease vector.
Dynamic Cascades for Face Detection (2007)

In this paper, we propose a novel method, called "dynamic cascade", for training an efficient face detector on massive data sets. There are three key contributions. The first is a new cascade algorithm called "dynamic cascade ", which can train cascade classifiers on massive data sets and only requires a small number of training parameters. The second is the introduction of a new kind of weak classifier, called "Bayesian stump", for training boost classifiers. It produces more stable boost classifiers with fewer features. Moreover, we propose a strategy for using our dynamic cascade algorithm with multiple sets of features to further improve the detection performance without significant increase in the detector's computational cost. Experimental results show that all the new techniques effectively improve the detection performance. Finally, we provide the first large standard data set for face detection, so that future researches on the topic can be compared on the same training and testing set.
Information Model for IP Flow Information Export (2008)

This memo defines an information model for the IP Flow Information
eXport (IPFIX) protocol. It is used by the IPFIX protocol for encoding
measured traffic information and information related to the traffic
Observation Point, the traffic Metering Process, and the Exporting
Process. Although developed for the IPFIX protocol, the model is
defined in an open way that easily allows using it in other protocols,
interfaces, and applications. [STANDARDS-TRACK]
Effects of hypoxia and hyperoxia on proteoglycan production by bovine pulmonary artery endothelial cells (1986)

Bovine pulmonary artery endothelial cells in culture were used to assess the influence of oxygen tension on proteoglycan synthesis. Cells exposed to 3% O2 (hypoxia) for 72 h and then labeled with [35S]sulfate for 5 h accumulated significantly less [35S]proteoglycan in medium than cells exposed to 20% O2 (control). This decrease was due primarily to a reduction in heparan sulfate. Cells exposed to 80% O2 (hyperoxia) for 72 h secreted slightly more [35S]proteoglycan into medium than controls. Greater accumulation of chondroitin sulfate was responsible for the increase. The amount of cell-associated proteoglycan did not change significantly in cells cultured in 3% or 80% O2 as compared with control cells cultured in 20% O2. Proteoglycans produced by hypoxia- or hyperoxia-treated cells were found to be similar in size to proteoglycans produced by cells cultured at 20% O2. Glycosaminoglycan sulfation, as measured by ion-exchange chromatography, did not appear to change with varying oxygen tensions. Our results demonstrate that production of proteoglycans secreted by endothelial cells in culture is sensitive to oxygen tension.
Electronic Communication through π‐Conjugated Wires in Covalently Linked Porphyrin/C<sub>60</sub> Ensembles (2005)

Novel photo- and electroactive triads, in which pi-conjugated p-phenylenevinylene oligomers (oPPVs) of different length are connected to a photoexcited-state electron donor (i.e., zinc tetraphenylporphyrin) and an electron acceptor (i.e., C(60)), were designed, synthesized, and tested as electron-transfer model systems. A detailed physicochemical investigation, concentrating mainly on long-range charge separation and charge recombination and kinetics, revealed small attenuation factors beta of 0.03+/-0.005 A(-1). Energy matching between the HOMO levels of C(60) and oPPVs emerged as a key parameter for supporting molecular-wire-like behavior: It favors rapid and efficient electron or hole injection into the oPPV wires. Large electronic coupling values were determined as a result of paraconjugation in the oPPV moieties.
Effect of size, disorder, and impurities on magnetism in FeAl (2001)

Theoretical electronic structure calculations have been carried out to investigate the effect of size, order, clustering, and impurities on the magnetism in FeAl. For the bulk alloys, the studies support the earlier view that the structural distortions and the Fe clustering are responsible for the magnetic order in the disordered alloy. As to the effect of size, it is shown that the recent observation of magnetism in the nanoparticles of FeAl is related to the presence of Fe sites close to or on the surface which acquire large magnetic moments due to reduced coordination. Finally, it is shown that it should be possible to make the ordered bulk nonmagnetic alloy magnetic by implanting nonmagnetic impurities like Pd or Rh.
Current bibliography of urban history (1983)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Crystallization and preliminary X-ray diffraction analysis of ω-amino acid:pyruvate transaminase from<i>Chromobacterium violaceum</i> (2007)

The enzyme omega-transaminase catalyses the conversion of chiral omega-amines to ketones. The recombinant enzyme from Chromobacterium violaceum has been purified to homogeneity. The enzyme was crystallized from PEG 4000 using the microbatch method. Data were collected to 1.7 A resolution from a crystal belonging to the triclinic space group P1, with unit-cell parameters a = 58.9, b = 61.9, c = 63.9 A, alpha = 71.9, beta = 87.0, gamma = 74.6 degrees . Data were also collected to 1.95 A from a second triclinic crystal form. The structure has been solved using the molecular-replacement method.
A histomorghometric study of screw‐shaped and removal torque titanium implants with three different surface topographies (1995)

Screw-shaped implants with 3 different surface topographies, evidenced visually as well as numerically with an optical profilometer, were inserted in rabbit bone. After a healing period of 12 weeks, a statistically significant higher removal torque was needed to unscrew screws blasted with 25-microns TiO2 particles and screws blasted with 75-microns particles of AI2O3 compared with screws with a turned surface. The histomorphometric evaluation demonstrated a higher percentage of bone-to-metal contact for implants blasted with 25-microns particles of TiO2 compared with the as-machined implants. A greater surface area of bone in threads was found for the turned screws compared with screws blasted with 25-microns TiO2 particles. In the short-term follow-up, there was a better fixation of implants with an average surface roughness of 0.9-1.3-microns and with a homogeneous surface structure than of implants with an average surface roughness of 0.4 microns and with a clear direction of the surface pattern.
A Review of the Health Benefits of Cherries (2018)

Increased oxidative stress contributes to development and progression of several human chronic inflammatory diseases. Cherries are a rich source of polyphenols and vitamin C which have anti-oxidant and anti-inflammatory properties. Our aim is to summarize results from human studies regarding health benefits of both sweet and tart cherries, including products made from them (juice, powder, concentrate, capsules); all referred to as cherries here. We found 29 (tart 20, sweet 7, unspecified 2) published human studies which examined health benefits of consuming cherries. Most of these studies were less than 2 weeks of duration (range 5 h to 3 months) and served the equivalent of 45 to 270 cherries/day (anthocyanins 55-720 mg/day) in single or split doses. Two-thirds of these studies were randomized and placebo controlled. Consumption of cherries decreased markers for oxidative stress in 8/10 studies; inflammation in 11/16; exercise-induced muscle soreness and loss of strength in 8/9; blood pressure in 5/7; arthritis in 5/5, and improved sleep in 4/4. Cherries also decreased hemoglobin A1C (HbA1C), Very-low-density lipoprotein (VLDL) and triglycerides/high-density lipoprotein (TG/HDL) in diabetic women, and VLDL and TG/HDL in obese participants. These results suggest that consumption of sweet or tart cherries can promote health by preventing or decreasing oxidative stress and inflammation.