gebhart/patrepeval huggingface dataset:
Electric vehicle integration in a real-time market (2014)

This project is rooted in the EDISON project, which dealt with Electrical Vehicle (EV) integration into the existing power grid, as well as with the infrastructure needed to facilitate the ever increasing penetration of fluctuating renewable energy resources like e.g. wind turbines. In the EDISON project, the EV is introduced as an energy buffer used to store excess energy produced at off-peak hours, while at the same time potentially benefiting the consumer by offering cheaper charging. This role as a buffer, predominantly used for delayed charging, also known as “smart charging”, can also be used for ancillary services to help stabilize the grid at critical periods, e.g. by providing near instant up- or down regulation. The initial goal of this project is to develop the components for a simulation platform for large scale EV integration studies. By interfacing the EV simulation with an externally simulated model of the power grid, it is be possible, in real-time, to simulate the impact of EV charging and help to identify bottlenecks in the system. In EDISON the vehicles are aggregated using an entity called a Virtual Power Plant (VPP); a central server monitoring and controlling the distributed energy resources registered with it, in order to make them appear as a single producer in the eyes of the market. Although the concept of a VPP is used within the EcoGrid EU project, the idea of more individual control is introduced through a new proposed real-time electricity market, where the consumers will have direct access to the current price. As opposed to the hourly spot-price market of today, the real-time market see price updates as often as every couple of minutes. To allow the individual resources to react to these changes, independent of each other, so called “smart controllers” are needed at the device level. In order for this market to work, however, the proper ICTnetwork- and server-infrastructure has to be developed. The primary goal of this PhD project, has been to investigate the scope of this ICT infrastructure, required to realise price-signal based charging of electric vehicles, in accordance with the EcoGrid EU market.
Entrapment of mRNA and rRNA into Large Monolamellar Liposomes Derived from Hybrid Small Monolamellar Liposomes (1978)

Conference Article| October 01 1978 Entrapment of mRNA and rRNA into Large Monolamellar Liposomes Derived from Hybrid Small Monolamellar Liposomes DANIEL H. WRESCHNER; DANIEL H. WRESCHNER *Divisions of Clinical Investigation and, Watford Road, Harrow, Middx. HA1 3WJ, U.K. Search for other works by this author on: This Site PubMed Google Scholar GREGORY GREGORIADIS; GREGORY GREGORIADIS *Divisions of Clinical Investigation and, Watford Road, Harrow, Middx. HA1 3WJ, U.K. Search for other works by this author on: This Site PubMed Google Scholar DAVID B. GUNNER; DAVID B. GUNNER †Electron Microscopy, Clinical Research Centre, Watford Road, Harrow, Middx. HA1 3WJ, U.K. Search for other works by this author on: This Site PubMed Google Scholar ROBERT R. DOURMASHKIN ROBERT R. DOURMASHKIN †Electron Microscopy, Clinical Research Centre, Watford Road, Harrow, Middx. HA1 3WJ, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1978) 6 (5): 930–933. https://doi.org/10.1042/bst0060930 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation DANIEL H. WRESCHNER, GREGORY GREGORIADIS, DAVID B. GUNNER, ROBERT R. DOURMASHKIN; Entrapment of mRNA and rRNA into Large Monolamellar Liposomes Derived from Hybrid Small Monolamellar Liposomes. Biochem Soc Trans 1 October 1978; 6 (5): 930–933. doi: https://doi.org/10.1042/bst0060930 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: Tes, 2-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino}ethanesulphonic acid This content is only available as a PDF. © 1978 Biochemical Society1978 Article PDF first page preview Close Modal You do not currently have access to this content.
Therapeutic-Class Wars -- Drug Promotion in a Competitive Marketplace (1994)

In today's prescription-drug marketplace a host of similar products compete for essentially the same population of patients. Between 1989 and 1993, for example, the Center for Drug Evaluation and Research of the Food and Drug Administration (FDA) approved 127 new molecular entities (excluding generic drugs), but only a minority offered a clear clinical advantage over existing therapies1. Many of the others are considered “me too” drugs because they are so similar to brand-name drugs already on the market. The preponderance of “me too” drugs has created a highly competitive marketplace for prescription drugs. Pharmaceutical companies are waging aggressive campaigns . . .
Role of histidine-related compounds to intracellular buffering in fish skeletal muscle (1985)

Histidine-related compounds (HRC) were analyzed in fish skeletal muscle as a means of identifying their precise role in intracellular buffering. Fish muscle was used because it contains two functionally and spatially distinct fiber types, red and white. Two fish species, rainbow trout (Salmo gairdneri) and the Pacific blue marlin (Makaira nigricans), were studied because these species demonstrate widely different activity patterns. Marlin red and white muscle buffer capacity was two times higher than trout with white muscle, buffering being two times greater than red in both species. Buffer capacity was highest in the 6.5-7.5 pH range for all tissues, which corresponded to their high anserine levels. The titrated HRC buffering was greater than the observed HRC buffering, which suggested that not all HRC were available to absorb protons. The HRC contribution to total cellular buffering varied from a high of 62% for marlin white to a low of 7% for trout red. The other principal buffers were found to be phosphate and protein with taurine contributing within red muscle in the 7.0-8.0 pH range. HRC were found to be dominant in skeletal muscle buffering by principally accounting for the buffering capacity differences found between the species and fiber types.
EDTV with scan-line video processor (1992)

An EDTV (extended definition TV) system implemented by the scan-line video processor (SVP), which is a general-purpose video processor for real-time video applications, is described. All the functions-motion detection, motion adaptive Y/C separation, contour compensation, chroma killer (ACK), and motion adaptive progressive scan conversion-were implemented by programming the SVP for the NTSC standard video signal.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
New Insights on the Antitumoral Properties of Prodiginines (2010)

Apoptosis is involved in the action of several (and perhaps all) cancer-chemotherapeutic agents. Prodiginines are a family of natural red pigmented secondary metabolites, produced by different bacteria and most of them are characterized by a common pyrrolylpyrromethene skeleton. The biosynthesis of prodigiosin and derivatives has been extensively studied in Serratia marcescens. S. marcescens is a Gramnegative bacterium belonging to Enterobacteriaceae. Prodiginines show numerous biological activities pointing out immunosuppressive and anticancer properties. Some prodiginines displayed apoptotic effects in vitro and antitumor activity in vivo. Their cytotoxic effect is attributed to the presence of the C- 6 methoxy substituent. The A-pyrrole ring plays a key role in both the copper nuclease activity and the cytotoxicity of prodiginines. Here we review the main characteristics of prodigiosin and their derivatives as well as the most prominent pharmacological activity of prodiginines and related compounds, including novel synthetic PG-derivatives with lower toxicity like GX15-070 (Obatoclax). The molecular targets of prodiginines are discussed and the mechanism of action for these molecules is a current topic in biomedicine with a real therapeutica potential in the clinic.
Airway neutral endopeptidase-like enzyme modulates tachykinin-induced bronchoconstriction in vivo (1988)

To determine whether neutral endopeptidase (NEP), also called enkephalinase (EC 3.4.24.11), modulates the effects of exogenous and endogenous tachykinins in vivo, we studied the effects of aerosolized phosphoramidon, a specific NEP inhibitor, on the responses to aerosolized substance P (SP) and on the atropine-resistant response to vagus nerve stimulation (10 V, 5 ms for 20 s) in guinea pigs. SP alone (10(-7) to 10(-4) M; each concentration, 7 breaths) caused no change in total pulmonary resistance (RL, P greater than 0.5). Phosphoramidon (10(-4) M, 90 breaths) caused no change either in base-line RL (P greater than 0.5) or in the response to aerosolized acetylcholine (P greater than 0.5). However, in the presence of phosphoramidon, SP (7 breaths) produced a concentration-dependent increase in RL at concentrations greater than or equal to 10(-5) M (P less than 0.001). Phosphoramidon (10(-7) to 10(-4) M; each concentration, 90 breaths) induced a concentration-dependent potentiation of SP-induced bronchoconstriction (10(-4) M, 7 breaths; P less than 0.01). Vagus nerve stimulation (0.5-3 Hz), in the presence of atropine, induced a frequency-dependent increase in RL (P less than 0.001). Phosphoramidon potentiated the atropine-resistant responses to vagus nerve stimulation (P less than 0.001) at frequencies greater than 0.5 Hz. The tachykinin antagonist [D-Arg1,D-Pro2,D-Trp7,9,Leu11]-substance P abolished the effects of phosphoramidon on the atropine-resistant response to vagus nerve stimulation (2 Hz, P less than 0.005). NEP-like activity in tracheal homogenates of guinea pig was inhibited by phosphoramidon with a concentration producing 50% inhibition of 5.3 +/- 0.8 nM.(ABSTRACT TRUNCATED AT 250 WORDS)
A New Method for Synthesizing a Pyrrole Ring and Its Application to the Development of New p-Systems (2001)

A new type of reaction was developed for the construction of a pyrrole ring.When 1,8-disubstituted 2,7-bis(p-tolylsulfonyl)-1,7-octadiene-3,6-diynes (6) was treated with an aniline derivative (7) in the presence of CuCl (1.6 equiv.)and CuCl 2 (0.16 equiv.) in DMF (at 90 o C), one 2-sulfonyl-1-alken-3-yne part of 6 was converted to a 1-arylpyrrole skeleton in a reasonable yield.A pyrrole ring (1) is known to be an important unit in many kinds of useful π-electron systems. 1 Among many methods for making this ring, the condensation of 1,4-diketones with an amine (the Paal-Knorr synthesis), 2 which is regarded as a [C4+N1]-type route, has been often utilized.A
Potentiality of Landsat, SPOT and IRS satellite imagery, for recognition of salt affected soils in Indian Arid Zone (1996)

Abstract Landsat, SPOT and IRS data, black and white and false colour composite (FCC) imagery of the summer (April, May), rainfed crop season (October) and winter irrigated crop season (January, February) of Indian Arid Zone were interpreted for recognition or three types of salt affected soils, viz. (1) natural salt affected; slight, moderate and severe, (2) saline soils due to saline water irrigation, (3) sodic soils due to high residual sodium carbonate (RSC) water irrigation. These were field checked and supported by analytical data. The Landsat-MSS band 4 could only provide the overall extent of salinity. The moderate and severe natural salt affected soils were identified by Landsat-MSS band 2, Landsat-MSS and TM, IRS LISS-I and LISS-II and SPOT HRV2 data for April and January. But the differentiation between the saline and sodic soils was possible only by the use of multi-date imagery (October and January) and the clue provided by the cropping pattern. The potentiality of remote sensing data products for identification of the types and degree of salt affected soils is discussed.
Carrier Coagulation of Chromite Fines in Wet Magnetic Separation (1993)

A "carrier" or "piggy–back" coagulation process was applied to improve the separation efficiency of chromite slimes in wet high–gradient magnetic separation. This was achieved by the addition of a coarse chromite fraction to the slime fraction (< 10 mm). Three coarse chromite fractions were investigated in the present study with size ranges <106>75, <75>53 and <53>38 μm. The results suggested that the <53>38 μm coarse fraction was the most effective in improving the process efficiency. Superior performance was also found to occur between pH 5 and 6. The results were discussed by computing the various components for potential energy of interaction between the slime particles and the "carrier" or "piggy‐back" particles at a range of surface potentials in the absence or presence of the magnetic field.
The <i>Drosophila stonewall</i> gene encodes a putative transcription factor essential for germ cell development (1996)

The differentiation of Drosophila germ cells is a useful model for studying mechanisms of cell specification. We report the identification of a gene, stonewall, that is required for germ cell development. Mutations in stonewall block proper oocyte differentiation and frequently cause the presumptive oocyte to develop as a nurse cell. Eventually, germ cells degenerate apoptotically. Stonewall is a germ cell nuclear protein; Stonewall has a DNA binding domain that shows similarities to the Myb and Adf-1 transcription factors and has other features that suggest that it is a transcription activating factor. We suggest that Stonewall transcriptional regulation is essential in cystocytes for maturation into specialized nurse cells and oocyte.
Adaptive Compressed Sensing Radar Oriented Toward Cognitive Detection in Dynamic Sparse Target Scene (2012)

Recently, the idea of compressed sensing (CS) has been used in radar system, and the concept of compressed sensing radar (CSR) has been proposed in which the target scene can be sparsely represented in the range-Doppler plane. With sufficiently incoherent transmission waveform, the target scene can be reconstructed by the technique of CS. With the idea that the transmission waveform can adapt in response to the operational information in cognitive radar system, we propose the notion of adaptive compressed sensing radar (ACSR) whose transmission waveform and sensing matrix can be updated by the target scene information fed back by the recovery algorithm. The methods for optimizing the transmission waveform and sensing matrix separately and simultaneously are both presented to decrease the cross correlations between different target responses. The principle for an ACSR system to synthesize the transmission waveform and sensing matrix matched to the target scene is also investigated. This novel ACSR system offers more degrees of freedom than classical radar system and better recovery performance than the CSR system.
On the incorporation of Mg and the role of oxygen, silicon, and hydrogen in GaN prepared by reactive molecular beam epitaxy (1997)

Mg-doped GaN samples prepared by reactive molecular beam epitaxy have been investigated in an attempt to gain insight into the impurity incorporation and the origin of auto doping in otherwise undoped GaN films. The Hall and secondary ion mass spectroscopy data were utilized for the analysis of possible background impurities such as Si, O, and H in an effort to ascertain whether the background electron concentration is of impurity origin or native defect origin. The data appear to support the N vacancy as a possible cause of auto-n-type doping seen in undoped GaN. The effect of the ammonia flow rate on the incorporation of Mg atoms in GaN films and on the behavior of H were studied for layers grown on c-plane sapphire as well as 6H–SiC. Increased incorporation of Mg with larger ammonia flow rates is attributed to Ga vacancies and accompanying site selection. Moreover, p-GaN films grown under high ammonia flux are reported with a hole concentration, mobility, and resistivity of about 8×1017 cm−3, 26 cm2/V s, and 0.3 Ω cm, respectively.
The bombyces and sphinges of the Ograzden Mountain in S.W. Bulgaria (Lepidoptera) (1988)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
ANALYSIS OF SOURCE LOCATION ALGORITHMS Part II: Iterative methods (2003)

Iterative algorithms are of particular importance in source location as they provide a much more flexible means to solve nonlinear equations, which is essential in order to deal with a wide range of practical problems. The most important iterative algorithms are Geiger’s method and the Simplex method. This article provides an overview of iterative algorithms as well as an in-depth analysis of several major methods. In Part I, we discussed the non-iterative location methods. A restriction that severely limits the application of these methods is the assumption of a single velocity for all channels. This assumption is not arbitrary or just for convenience; it is necessary in order to keep the source location equations in the simplest form so that they can be solved non-iteratively. In other words, the assumption is a reflection of an inherent difficulty associated with non-iterative location methods. If a single velocity model is not suitable, as in most cases, we have to turn to an iterative method. While the associated searching strategies may vary significantly, iterative methods in general refer to those algorithms that start from an initial solution, commonly called a guess or trial solution. This trial solution is tested by the given conditions, and then updated by the predefined schemes, which subsequently forms a new trial solution. Therefore, iterative methods, in essence, are a process of testing and updating trial solutions.
Modeling context-based security policies with contextual graphs (2004)

Security is top priority for pervasive applications, for which the number of reported incidents is in constant increase. Context-based security is an emerging approach. It aims at coping with the security problems resulting from the high heterogeneity and dynamicity of such environments. In this paper, we propose a new model for policies specification based on contextual graphs. It relies on a set of contextual information collected from the system and user's environments. This approach aims at providing a convenient way for modeling security requirements in complex systems.
Steganalysis of LSB Matching Using Characteristic Function Moment of Pixel Differences (2016)

Nowadays,many steganographic tools have been developed,and secret messages can be imperceptibly transmitted through public networks.This paper concentrates on steganalysis against spatial least significant bit(LSB) matching,which is the prototype of many advanced information hiding methods.Many existing algorithms deal with steganalysis problems by using the dependencies between adjacent pixels.From another aspect,this paper calculates the differences among pixel pairs and proves that the histogram of difference values will be smoothed by stego noises.We calculate the difference histogram characteristic function(DHCF) and deduce that the moment of DHCFs(DHCFM) will be diminished after stego bits are hidden in the image.Accordingly,we compute the DHCFMs as the discriminative features.We calibrate the features by decreasing the influence of image content on them and train support vector machine classifiers based on the calibrated features.Experimental results demonstrate that the DHCFMs calculated with nonadjacent pixels are helpful to detect stego messages hidden by LSB matching.
The gastric anti-ulcer activity of naringenin, a specific histidine decarboxylase inhibitor. (1983)

The gastric anti-ulcer activity of a specific histidine decarboxylase inhibitor naringenin, the aglycone of naringin, a naturally occurring flavanone glycoside obtained from kino and grapefruits, has been studied on the various types of ulcers experimentally induced in rats, viz., pylorus-ligated (Shay method) and restraint ulcers, and on the gastric mucosal damage induced by aspirin, phenylbutazone or reserpine. Naringenin possessed significant anti-ulcer activity in all these models, manifesting a dose-dependent anti-ulcer effect on the pylorus-ligated and restraint ulcers. However, the ED50 value against ulcers in the pylorus-ligated rats (132 mg/kg) was significantly greater than that against ulcers in the restraint rats (42 mg/kg). Amongst all the models used, naringenin was found most effective against the restraint rats. It is suggested that a mechanism involving the inhibition of formation and release of endogenous histamine in the gastric mucosa of rats is implicated in the protective effect of naringenin.
Scalable Quantum Computing with "Enhancement" Quantum Dots (2005)

We propose a novel scheme of solid state realization of a quantum computer based on single spin "enhancement mode" quantum dots as building blocks. In the enhancement quantum dots, just one electron can be brought into initially empty dot, in contrast to depletion mode dots based on expelling of electrons from multi-electron dots by gates. The quantum computer architectures based on depletion dots are confronted by several challenges making scalability difficult. These challenges can be successfully met by the approach based on ehnancement mode, capable of producing square array of dots with versatile functionalities. These functionalities allow transportation of qubits, including teleportation, and error correction based on straightforward one- and two-qubit operations. We describe physical properties and demonstrate experimental characteristics of enhancement quantum dots and single-electron transistors based on InAs/GaSb composite quantum wells. We discuss the materials aspects of quantum dot quantum computing, including the materials with large spin splitting such as InAs, as well as perspectives of enhancement mode approach in materials such as Si.