gebhart/patrepeval huggingface dataset:
Identification and characterization of two distinct alpha-(1-3)-L-fucosyltransferase activities in human colon carcinoma. (1990)

Two distinct alpha-(1-3)-fucosyltransferase activities have been identified in the colon carcinoma cell lines HT-29 and COLO-205. While both enzymatic activities exhibit similar affinities for a synthetic alpha-(1-3) acceptor and GDP-fucose, they differ with respect to divalent cation requirements, N-ethylmaleimide inhibition, and glycoprotein substrate specificity. The COLO-205 alpha-(1-3) activity exhibits maximal enzymatic activity in the presence of 20 mM Mn2+ but retains less than 10% activity in the absence of divalent cations. In contrast, the optimal Mn2+ concentration for the HT-29 enzyme is 1 mM, although this activity is relatively insensitive to divalent cation stimulation. In addition, the HT-29 alpha-(1-3)-fucosyltransferase activity is resistant to inhibition by 30 mM N-ethylmaleimide and relatively inactive toward the glycoprotein substrate fetuin as compared to its desialylated derivative, asialofetuin. The COLO-205 activity is inhibited approximately 90% by N-ethylmaleimide and is equally active with either glycoprotein acceptor. Although the alpha-(1-3) specific activities are similar in both cell lines, N-ethylmaleimide-sensitive alpha-(1-4) fucosyltransferase activity is 40-fold higher in COLO-205 as compared to HT-29, suggesting that the COLO-205 fucosyltransferase activity may be an alpha-(1-3/4) enzyme, while the HT-29 activity appears to be an alpha-(1-3) specific form. Further examination of a panel of cell lines, tumor biopsies, and xenografts, based on the effect of metal ions and N-ethylmaleimide, indicated that both enzyme activities are similarly expressed in human colon carcinoma tissue.
Dioxirane Epoxidation of 10-Membered-Ring Stilbene Lactams as Synthetic Precursors to Protoberberines (1999)

Silylated stilbene lactams 1, prepared by intramolecular addition of an aryl radical to a trimethylsilylacetylene, were converted into protoberberines by dimethyldioxirane (DMD) epoxidation and subsequent acid-catalyzed cyclization of the epoxysilane with HCl. Treatment of the nonsilylated trans- and cis-stilbene derivatives with DMD afforded 13-hydroxytetrahydroprotoberberines and 13a-hydroxy-13-ketotetrahydroprotoberberines as the main products. Tetrahydroprotoberberines were also obtained in excellent yields by the reaction of both silylated and nonsilylated lactams with hydriodic acid.
Production and Health of Pasture-Fed Dairy Cattle Following Oral Treatment with the Ionophore Lasalocid (2004)

The aim of the study was to evaluate the effect of feeding the ionophore lasalocid on the productivity and health of seasonally calving, pasture-fed dairy cows. Dairy cows (n = 1020) from 4 herds were enrolled in a split-herd, prospective intervention study. Cows were blocked by breed and age, ranked on previous production, and then assigned to 2 treatment groups. Treatment cows were each exposed to 300 to 350 mg of lasalocid/d commencing 3 wk before and ending 18 wk after the start of the seasonal calving period. Milk production was determined on 3 occasions for each cow at approximately monthly intervals (herd tests 1 to 3), body condition score was determined fortnightly, and all disease occurrences were recorded. Lasalocid treatment increased milk volume milk protein and milk fat production by approximately 2%, without altering milk composition. Fewer lasalocid-treated cows than control cows (7.3 vs. 11.6%, respectively) were diagnosed with clinical mastitis. Lasalocid treatment of pasture-fed dairy cows resulted in reduced mastitis incidence and increased milk production without changes in body condition or negative effects on metabolic processes as monitored by metabolite concentrations.
Whisper: a spread spectrum approach to occlusion in acoustic tracking (2002)

NICHOLAS MICHAEL VALLIDIS. WHISPER: A Spread Spectrum Approach to Occlusion in Acoustic Tracking. (Under the direction of Gary Bishop.) Tracking systems determine the position and/or orientation of a target object, and are used for many different purposes in various fields of work. My focus is tracking systems in virtual environments. While the primary use of tracking for virtual environments is to track the head position and orientation to set viewing parameters, another use is body tracking—the determination of the positions of the hands and feet of a user. The latter use is the goal for Whisper. The largest problem faced by body-tracking systems is emitter/sensor occlusion. The great range of motion that human beings are capable of makes it nearly impossible to place emitter/sensor pairs such that there is always a clear line of sight between the two. Existing systems either ignore this issue, use an algorithmic approach to compensate (e.g., using motion prediction and kinematic constraints to “ride out” occlusions), or use a technology that does not suffer from occlusion problems (e.g., magnetic or mechanical tracking devices). Whisper uses the final approach. In this dissertation I present Whisper as a solution to the body-tracking problem. Whisper is an acoustic tracking system that uses a wide bandwidth signal to take advantage of low frequency sound’s ability to diffract around objects. Previous acoustic systems suffered from low update rates and were not very robust of environmental noise. I apply spread spectrum concepts to acoustic tracking in order to overcome these problems and allow simultaneous tracking of multiple targets using Code Division Multiple Access.
A biomimetic jellyfish robot based on ionic polymer metal composite actuators (2009)

A biomimetic jellyfish robot based on ionic polymer metal composite actuators was fabricated and activated to mimic real locomotive behavior with pulse and recovery processes. To imitate the curved shape of the jellyfish, a thermal treatment was applied to obtain a permanent initial deformation of a hemispherical form. The bio-inspired input signal was generated for mimicking real locomotion of the jellyfish. The vertical floating displacement and the thrust force of the biomimetic jellyfish robot under various input signals were measured and compared. The present results show that the bio-inspired electrical input signal with pulse-recovery process generates much higher floating velocity of the biomimetic jellyfish robot in comparison with pure sinusoidal excitations. The curved shape of the IPMC actuator through thermal treatments can be successfully applied to mimic the real biomimetic robots with smooth curves.
Scaling Millimeter-Wave Networks to Dense Deployments and Dynamic Environments (2019)

Millimeter-wave (mmWave) communications have emerged as one of the most promising options to vastly increase wireless data rates due to the high bandwidth they offer. Given the high path loss at mmWave frequencies, such systems require directional antennas to achieve a good communication range. Thus, the communicating devices need to align the beam directions of their mmWave antennas. Due to the high penetration loss, the paths between the antennas also need to be free of blocking obstacles. This makes an efficient and reliable operation of mmWave networks in dynamic environments very challenging. At the same time, the directionality reduces interference and allows to scale these networks to much higher access point and device densities. In this paper, we discuss the above-mentioned challenges and present techniques that allow mmWave networks to scale to high-density deployments, to adapt to dynamic and mobile environments, and to consistently achieve high data rates. This includes learning the environment to find different propagation paths, reacting timely to channel impairments such as blockage, and integrating mmWave networks with networks operating at a lower frequency for robustness. A key ingredient to enable these forms of adaptivity is the use of location information. Such mechanisms then turn a collection of very-high-speed but brittle mmWave links into an efficient, low-latency, and reliable network.
Hydrogen Transport through Tubular Membranes of Palladium-Coated Tantalum and Niobium (1996)

Palladium-based membranes have been used for decades in hydrogen extraction because of their high permeability and good surface properties and because palladium, like all metals, is 100% selective for hydrogen transport. We describe experiments with hydrogen-extraction membranes made of palladium-coated niobium and tantalum heat-exchanger tubes. The cost was about $45/ft of 3/8 in. tubular membrane, and the fluxes were as high as 0.001 47 mol/m2 s Pa1/2 at 420 °C. The main transport resistance is in the refractory metal substrate. Durability tests showed a 15% reduction in flux for 31 days of continuous membrane operation. Assuming durability is maintained for at least 1 year, this price and flux should allow competitive application for hydrogen recovery in petrochemical plants and for membrane reactors.
Piano Duet Repertoire: Music Originally Written for One Piano, Four Hands (1981)

Preface Acknowledgments General Explanations Abbreviations Index of Music Publishers Index of Library Locations Piano Duet Repertoire Appendix I: Collections of Four-Hand Music Appendix II: Music for Piano, Four Hands with Voice(s) and/or Other Instrument(s) Select Bibliography
Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society* Clinical Practice Guideline (2018)

Newborn screening Cost-effectiveness 1.1 We recommend that all newborn screening programs incorporate screening for congenital adrenal hyperplasia due to 21-hydroxylase deficiency. (1|s) 1.2 We recommend that first-tier screens use 17hydroxyprogesterone assays standardized to a common technology with norms stratified by gestational age. (1|s) Technical remark: Clinicians should be aware that immunoassays are still in use and remain a source of false-positive results. Specificity may be improved with organic extraction to remove cross-reacting substances. 1.3 We recommend that screening laboratories employ a second-tier screen by liquid chromatographytandem mass spectrometry in preference to all other
Editorial - Microdosimetric Counters in Radiation Protection (1984)

Editorial - Microdosimetric Counters in Radiation Protection Get access J. Booz, J. Booz Search for other works by this author on: Oxford Academic PubMed Google Scholar A.A. Edwards, A.A. Edwards Search for other works by this author on: Oxford Academic PubMed Google Scholar K.G. Harrison K.G. Harrison Search for other works by this author on: Oxford Academic PubMed Google Scholar Radiation Protection Dosimetry, Volume 9, Issue 3, 1 November 1984, Page 141, https://doi.org/10.1093/oxfordjournals.rpd.a083082 Published: 01 November 1984
Visualization of hepatitis C virions and putative defective interfering particles isolated from low‐density lipoproteins (1996)

Hepatitis C virus (HCV) in highly infectious sera has been shown to be predominantly associated with low-density lipoproteins. To determine whether the association is specific to low-density lipoproteins (LDL) or very low-density lipoproteins (VLDL), we fractionated HCV-containing plasma by a column chromatographic procedure known to separate these classes. Hepatitis C virus RNA detected by polymerase chain reaction (PCR) was associated primarily with the very low-density (VLDL) fraction. However, it could not be ruled out that virus-associated LDL may have eluted with this fraction. Hepatitis C virus virions isolated from sera having sufficient titre for visualization by electron microscopy are generally coated with antiviral antibodies, therefore we utilized the lipid association to isolate antibody-free virions. Very low-density lipoproteins were isolated by ultracentrifugal flotation and then treated with deoxycholate to release the virions. These were then isolated in a highly purified form by centrifugation in a sucrose gradient. The 1.10-1.11 g ml-1 region of the gradients contained 60-70 nm particles. Particles with similar surface structure but having a diameter of only 30-40 nm constituted about 30% of the total. The latter may represent defective interfering particles. The identity of both small and large particles with HCV virions and associated particles was confirmed by their trapping on grids by an anti-HCV E2 monoclonal antibody, and by their aggregation by rabbit antiserum to an amino-terminal peptide of E1. Thus, both E1 and E2 epitopes are displayed on the surface of intact HCV virions.
Estimating Gaussian Mixture Models from Data with Missing Features (1996)

Maximum likelihood #ML# #tting of Gaussian mixture models #GMMs# to feature data is most e#ciently handled by the EM algorithm #1, 2, 3, 4#. The EM algorithm is directly applicable to multivariate data in which all the features are always present, and there are no missing values. Unfortunately, missing values are common: caused either by random or systematic e#ects. This study presentsanovel algorithm for estimating the parameters of GMMs when there are random missing values. The approachisBayesian in the missing values and ML in the GMM parameters. The same model can be applied to heteroscedastic data, and to indirectly observable mixed Gaussian observations. 1. INTRODUCTION Conventionally, Gaussian mixture models are used to model the density of feature data for which there is no a priori parametric model. GMMs are highly #exible: with an in#- nite supply of components, they can model densities of arbitrary complexity. Their use has become widespread since the development of the EM...
SQUIDS and their applications in the measurement of weak magnetic fields (1980)

The development of weak magnetic field measurement techniques based on the superconducting devices known as SQUIDS has led to both an increase in interest in this traditional area and the opening up of new areas of application. In particular, the weak fields associated with the human body are being increasingly studied. This review first outlines both the theory and operation of SQUID systems. After a brief survey of alternative instruments some experiments representing possible major applications of SQUID systems are discussed. Finally a forecast is made of the progress to be expected in the next few years.
An artificial neural network modeling for pipeline corrosion growth prediction (2015)

Corrosion defect assessment becoming a forte issue in pipeline reliability assessment to accurately predict the severity of its condition. Due to the uncertainties inherit from the pipeline inspection at present, statistical model use to model the corrosion growth apply a correctional methods to reduce the gap (means and variation) between predicted values and the actual data. This study aims to develop a time dependent corrosion growth model for oil and gas pipeline using Artificial Neural Network (ANN) as an alternative to the current method and to evaluate its applicability without enforcing data correctional methods. This model is formulated based on parameters of defect extracted from in-line inspection data (ILI) and quantified by statistical analysis. The develop model gives the prediction of the corrosion depth and length of the defect that can be used to calculate the corrosion rate or growth. The results and outcome of the present study can help pipeline operators to predict the reliability of the pipeline structure in terms of its probability of failure or lifetime estimation
UROCANIC ACID AS AN IMMUNOSUPPRESSANT IN ALLOTRANSPLANTATION IN MICE (1993)

Urocanic acid (UCA) was investigated for its activity as an immunosuppressive agent in murine heterotopic allotransplantation. Mice grafted with cornea, pancreas, and skin under the renal capsule were given either intravenous, subcutaneous, or topical cis-UCA in the peritransplant period. Grafts were performed across complete and minor MHC barriers. Peritransplant immunosuppression with cis-UCA prolonged survival of these grafts, but no route of administration was clearly superior to another. Survival of cornea was prolonged more than survival of skin or pancreas in all MHC disparate combinations. cis-UCA was also used to assess its effect on stimulator cells, derived from mice that had received UCA, in mixed lymphocyte responses. cis-UCA adversely affected the ability of stimulator cells to provoke T cell proliferation in an allogeneic MLR. These findings suggest that cis-UCA may be a potentially useful immunosuppressive agent.
An adaptive outdoor terrain classification methodology using monocular camera (2010)

An adaptive partition based Random Forests classifier for outdoor terrain classification is presented in this paper. The classifier is a combination of two underlying classifiers. One of which is a random forest learnt over bootstrapped or offline dataset, the second is another random forest that adapts to changes on the fly. Posterior probabilities of both the static and changing/online classifiers are fused to assign the eventual label for the online image data. The online classifier learns at frequent intervals of time through a sparse and stable set of tracked patches, which makes it lightweight and real-time friendly. The learning which is actuated at frequent intervals during the sojourn significantly improves the performance of the classifier vis-a-vis a scheme that only uses the classifier learnt offline or at bootstrap. The method is well suited and finds immediate applications for outdoor autonomous driving where the classifier needs to be updated frequently based on what shows up recently on the terrain and without largely deviating from those learnt at bootstrapping. The role of the partition based classifier to enhance the performance of a regular multi class classifier such as random forests and multi class SVMs is also summarized in this paper.
Hydrolysis of amides by extracts from mycobacteria (1957)

Research Article| April 01 1957 Hydrolysis of amides by extracts from mycobacteria Y. S. Halpern; Y. S. Halpern 1Department of Bacteriology, Hebrew University-Hadassah Medical School, Jerusalem, Israel Search for other works by this author on: This Site PubMed Google Scholar N. Grossowicz N. Grossowicz 1Department of Bacteriology, Hebrew University-Hadassah Medical School, Jerusalem, Israel Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1957) 65 (4): 716–720. https://doi.org/10.1042/bj0650716 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation Y. S. Halpern, N. Grossowicz; Hydrolysis of amides by extracts from mycobacteria. Biochem J 1 April 1957; 65 (4): 716–720. doi: https://doi.org/10.1042/bj0650716 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1957 CAMBRIDGE UNIVERSITY PRESS1957 Article PDF first page preview Close Modal You do not currently have access to this content.
A simple fluorescent technique for the location of tumour cells in frozen sections of the head and neck region. (1991)

Tumour cells possess cell surface proteases referred to as guanidinobenzoatase (GB) which are closely similar to plasminogen activator. Previous studies have demonstrated different isoenzymic forms of GB on tumour cells and normal cells which can be recognised by cytoplasmic protein inhibitors extracted from frozen sections of appropriate tissues. We now show that normal human serum possesses inhibitors which selectively recognise the isoenzymic forms of GB associated with normal cell surfaces but do not recognise the GB on tumour cell surfaces in frozen sections of tissue obtained from the head and neck regions.
Controlling Energy-Level Alignments at Carbon Nanotube/Au Contacts (2003)

The properties of the contacts between single-walled carbon nanotubes (SWNTs) and Au electrodes are studied using scanning Kelvin probe and electrostatic force microscopies. Contact potential differences and local dipoles at the SWNT/Au interface are determined under various conditions involving gas adsorption and surface passivation. In particular, the effects of the coadsorption of alkanethiol, S, and O2 are explored in detail. We find that the coadsorbates alter the energy-level line-up at the contacts and induce significant shifts of the SWNT bands relative to the metal Fermi level. This behavior is explained by considering the response of the local Au work function to the presence of the nanotube and of the coadsorbates as well as the effects of the adsorbate dipoles near the contacts. Finally, we use coadsorption to control the Schottky barrier height at the nanotube−Au contacts.
<i>Spotted leaf11</i>, a Negative Regulator of Plant Cell Death and Defense, Encodes a U-Box/Armadillo Repeat Protein Endowed with E3 Ubiquitin Ligase Activityw (2004)

The rice (Oryza sativa) spotted leaf11 (spl11) mutant was identified from an ethyl methanesulfonate-mutagenized indica cultivar IR68 population and was previously shown to display a spontaneous cell death phenotype and enhanced resistance to rice fungal and bacterial pathogens. Here, we have isolated Spl11 via a map-based cloning strategy. The isolation of the Spl11 gene was facilitated by the identification of three additional spl11 alleles from an IR64 mutant collection. The predicted SPL11 protein contains both a U-box domain and an armadillo (ARM) repeat domain, which were demonstrated in yeast and mammalian systems to be involved in ubiquitination and protein-protein interactions, respectively. Amino acid sequence comparison indicated that the similarity between SPL11 and other plant U-box-ARM proteins is mostly restricted to the U-box and ARM repeat regions. A single base substitution was detected in spl11, which results in a premature stop codon in the SPL11 protein. Expression analysis indicated that Spl11 is induced in both incompatible and compatible rice-blast interactions. In vitro ubiquitination assay indicated that the SPL11 protein possesses E3 ubiquitin ligase activity that is dependent on an intact U-box domain, suggesting a role of the ubiquitination system in the control of plant cell death and defense.
Characterization of dimensional effects in ferrite-core magnetic devices (2002)

Large ferrite cores used in high-power, high-frequency applications can experience dimensional effects that limit the bandwidth of the device and cause losses higher than those predicted by manufacturer's datasheets. This paper examines such effects in Mn-Zn cores of various sizes and presents corroborating measurement and simulation data that illustrate the impact of both dimensional resonance and eddy-current losses in large cores.
A Secondary, Nonaqueous Solvent Battery (1971)

The feasibility of a room‐temperature, nonaqueous organic solvent, electrochemical cell that can deliver 10 mA/cm2 at 4V has been demonstrated. The cell consists of a lithium negative, a graphite compound positive electrode, and a lithium perchlorate‐dimethyl sulfite electrolyte solution. The cell develops an open‐circuit potential of approximately 4.5V. Apparently the lithium perchlorate‐dimethyl sulfite electrolyte undergoes no or least slow oxidation or reduction within a 4.5V range.
Speckle reduction in laser-illuminated picoprojectors (2012)

Speckle can seriously degrade image quality in laser-illuminated projection displays. Various solutions appropriate to small microdisplay-based projectors are presented. Illumination optical system and projection optical system design are discussed in order to better understand the critical constraints of size, power consumption, optical efficiency, and performance. DYOPTYKA's innovative solution, using a phase randomizing deformable mirror, is described.