gebhart/patrepeval huggingface dataset:
Telecommunications services management with computational reflection, using CORBA and JAVA (2002)

Currently, telecommunications management systems are powerful, however, they maintain centralized and proprietary platforms, limiting in this way, the growth of these telecommunications networks. This factor generates the need for scalable and open systems, stimulating the sectors of the telecommunications area to seek for solutions to problems in distributed, heterogeneous and totally scalable environments. The recent advances in the area of distributed objects has created many positive expectations for the development of client/server systems which use, as if they were local, resources available through the network. The objective of this work consists of the experimental evaluation of the potential of the main CORBA services in conjunction with the Java language, through the necessary requirements for the main functionalities proposed by the TMN architecture. For the implementation of telecommunication services with reusability of code we use computational reflection with meta-classes substituting the manager and classes substituting the agents.
Facile Domino Access to Chiral Bicyclo[3.2.1]octanes and Discovery of a New Catalytic Activation Mode (2010)

A highly enantio- and diastereoselective organocatalytic domino Michael-Henry process for the preparation of synthetically unique and medicinally important bicyclo[3.2.1]octane derivatives with four stereogenic centers including two quaternary stereocenters has been developed. Theoretical DFT calculations on the transition states have been carried out to reveal origins of the excellent stereoselectivities. A novel dual model was thus proposed.
The Intestinal Microbiota in Metabolic Disease (2016)

Gut bacteria exert beneficial and harmful effects in metabolic diseases as deduced from the comparison of germfree and conventional mice and from fecal transplantation studies. Compositional microbial changes in diseased subjects have been linked to adiposity, type 2 diabetes and dyslipidemia. Promotion of an increased expression of intestinal nutrient transporters or a modified lipid and bile acid metabolism by the intestinal microbiota could result in an increased nutrient absorption by the host. The degradation of dietary fiber and the subsequent fermentation of monosaccharides to short-chain fatty acids (SCFA) is one of the most controversially discussed mechanisms of how gut bacteria impact host physiology. Fibers reduce the energy density of the diet, and the resulting SCFA promote intestinal gluconeogenesis, incretin formation and subsequently satiety. However, SCFA also deliver energy to the host and support liponeogenesis. Thus far, there is little knowledge on bacterial species that promote or prevent metabolic disease. Clostridium ramosum and Enterococcus cloacae were demonstrated to promote obesity in gnotobiotic mouse models, whereas bifidobacteria and Akkermansia muciniphila were associated with favorable phenotypes in conventional mice, especially when oligofructose was fed. How diet modulates the gut microbiota towards a beneficial or harmful composition needs further research. Gnotobiotic animals are a valuable tool to elucidate mechanisms underlying diet-host-microbe interactions.
PHYTOPLANKTON-BASED BIOMONITORING IN ASSESSING THE POLLUTION LEVEL OF A LENTIC FRESHWATER BODY IN HOOGHLY DISTRICT, WEST BENGAL, INDIA (2020)

Phytoplankton is the base of every aquatic food web. During the assessment of the trophic status of the investigated lentic water body (within Lake City Housing Complex, Mankundu, Hooghly, West Bengal, India), phytoplankton composition and its temporal variation are proved to be the most important. In this study, 30 phytoplankton taxa have been recorded in various arrangements throughout the season. The maximum number of phytoplankton species with the highest Shannon–Weaver diversity index value represented the pre-monsoon season, whereas the least number of phytoplankton taxa and the lowest diversity indicators characterized the post-monsoon season. The development of algal bloom by one specific taxon, Botryococcus braunii, in the postmonsoon season indicates the change in the trophic status of this particular water body. As a criterion for the beginning of the algal bloom, an exceedance of 1 mg/L in nitrate concentration can be considered. The phytoplankton composition, values of various diversity indices, its density and species distribution pattern, and selected environmental parameters have been investigated, as well as the results of the analysis of rank abundance curves, which allowed for evaluation of the ecological status of this lentic water body. This study describes the change or shift in the ecosystem of the investigated water body towards eutrophication and establishes its pollution level as moderate to light.
Development of next generation carpet backings for facile recyclability (2006)

The overall goal of the research was to develop the next generation, generic\nconstruction of broadloom carpet that will compete on both a performance and cost basis\nwith the current construction while avoiding the major recycling disadvantages of the\nlatter. The new construction was designed to maintain nearly all of the current carpet\nformation processes to minimize capital investment in converting existing manufacturing\nlines. A major industry constriction was that the new construction must at least meet the\ncurrent construction's physical performance on the floor and overall cost characteristics.
Photodynamically Inactivated Vaccines Prepared by Growing Viruses in Cells Containing Neutral Red (1967)

Summary Three enteroviruses (echovirus type 7, coxsackieviruses B3 and A9), herpes simplex virus, and vaccinia virus were grown in cells that had been pretreated with neutral red. Even though the harvests were visibly free of dye, the virus progency had become totally sensitive to light. Photodynamically inactivated vaccines yielded immune responses in rabbits superior to those with formalinized vaccines. Neutralizing antibody-combining tests also showed that the photodynamically inactivated vaccines were antigenically more potent, for they bound more antibody than was bound by formalinized preparations.
Classification of wideband transient signals using spectral-based techniques (2002)

Spectral-based classification schemes designed to separate various wideband transient signals are considered and their performances compared to those obtained using a back-propagation neural network implementation. Spectral-based measures considered include the Bhattacharyya distance, the divergence, the normalized cross-correlation coefficient, and the modified normalized cross-correlation coefficient. Results show that accurate classification may be obtained using spectral-based measures and that the performances compare, or are sometimes better, to those obtained using neural networks when the training data used to train the neural network is small. In addition, the spectral-based measures are simple and computationally inexpensive.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Tip-Sample Interaction in Atomic Force Microscopy and its Implications for Biological Applications. (1993)

This thesis describes the construction of an atomic force microscope and its application to the study of tip-sample interactions, primarily through the use of friction and hardness (elasticity) imaging.

Part one describes the atomic force microscope, which consists of a scanned-cantilever stage (chapter 2); a versatile digital signal processor-based control system with self-optimizing feedback, lock-in amplifier emulation (for hardness imaging), and macro programmability (chapter 3); and image processing software (chapter 4).

Part two describes a number of results that have helped to characterize the tip-sample interaction and the contact imaging modes used for its study. Meniscus forces act laterally as well as normally, and that they vary with position (chapter 5). Friction measurements couple with scanner position quid feedback, and the meniscus effects friction images (chapter 6). Sliding of the tip over the sample surface introduces slope-dependence into hardness measurements (chapter 7). Dull tips can create prominent topography artifacts even on very flat surfaces (chapter 8).

In an investigation of collagen fibrils, AFM has revealed die characteristic 65 nm banding pattern, a second, minor banding pattern, and microfibrils that run along the fibril axis. The distribution of proteoglycans along the fibrils creates a characteristic pattern in friction images. Although imaging in water reduces interaction forces, water can also make biological samples more sensitive to force. However, for robust biological samples imaged in air, tip shape presents a greater obstacle than tip-sample interaction forces to obtaining high-resolution images. Tip contamination increases tip-sample friction and can occasionally improve resolution (chapter 9).

For a separate project I have designed a general-purpose nearfield scanning optical microscope (chapter 10).
Efficient HRTF-based Spatial Audio for Area and Volumetric Sources (2016)

We present a novel spatial audio rendering technique to handle sound sources that can be represented by either an area or a volume in VR environments. As opposed to point-sampled sound sources, our approach projects the area-volumetric source to the spherical domain centered at the listener and represents this projection area compactly using the spherical harmonic (SH) basis functions. By representing the head-related transfer function (HRTF) in the same basis, we demonstrate that spatial audio which corresponds to an area-volumetric source can be efficiently computed as a dot product of the SH coefficients of the projection area and the HRTF. This results in an efficient technique whose computational complexity and memory requirements are independent of the complexity of the sound source. Our approach can support dynamic area-volumetric sound sources at interactive rates. We evaluate the performance of our technique in large complex VR environments and demonstrate significant improvement over the naive point-sampling technique. We also present results of a user evaluation, conducted to quantify the subjective preference of the user for our approach over the point-sampling approach in VR environments.
Expected gains from parallelizing constraint solving for hard problems (1994)

A number of recent studies have examined how the difficulty of various NP-hard problems varies with simple parameters describing their structure. In particular, they have identified parameter values that distinguish regions with many hard problem instances from relatively easier ones. In this paper we continue this work by examining independent parallel search. Specifically, we evaluate the speedup as function of connectivity and search difficulty for the particular case of graph coloring with a standard heuristic search method. This requires examining the full search cost distribution rather than just the more commonly reported mean and variance. We also show similar behavior for a single-agent search strategy in which the search is restarted whenever it fails to complete within a specified cost bound.
Series-stacked medium voltage electronic voltage regulator (2011)

This paper discusses the development of a series-stacked medium-voltage electronic voltage regulator for the purpose of regulating the voltage on a 22 kV three-phase transmission line. The three-phase regulator consists of three independent 12.75 kV regulator cells, connected in a star configuration. Each regulator cell consists of an autotransformer with one common and two series windings. An AC-to-AC voltage converter is connected to each series winding in order to accurately regulate the amount with which the line voltage is boosted. This allows for a 10% regulation of the line voltage using two AC-to-AC converter modules. With the modular approach, higher voltages can be attained by simply adding more AC-to-AC converter modules to an appropriate transformer. An alternative AC-to-AC converter topology is implemented and appropriate protection mechanisms are discussed. The system is verified using simulation and practical results and the concept proves to be feasible and practical.
Application of fuzzy cellular neural networks to Euclidean distance transformation (1997)

A new structure of fuzzy cellular neural network (FCNN) is proposed. In this FCNN, the relationship between fuzzy templates and input or/and output is defined by addition but not multiplication. Unlike the FCNN we proposed previously, which can only implement morphological operators with flat structuring elements, this FCNN can implement morphological operators with all the types of structuring elements. This FCNN is used to implement Euclidean distance transform. Simulation results are given.
Involvement of steroids in anti‐inflammatory effects of PK11195 in a murine model of pleurisy (2004)

BACKGROUND : Studies on peripheral benzodiazepine receptor function have yielded a diverse list of activities of which the anti‐inflammatory effects need to be further examined. Aims : To evaluate the role of steroids, nitric oxide and adenosine‐deaminase in the anti‐inflammatory effect of PK11195. Methods : Pleurisy was induced by intrapleural injection of carrageenan in mice pre‐treated or not with PK11195. Leukocytes, exudation, adenosine‐deaminase (ADA) activity and nitric oxide (NO) level were measured. Steroid involvement was evaluated by pre‐treatment with D,L‐aminogluthetimide before PK11195. Results : Leukocytes, exudation and NO levels were reduced by PK11195 in the early (4 h) phase. In the late (48 h) phase, PK11195 decreased leukocytes and ADA activity. D,L‐aminogluthetimide reversed the effect of PK11195 on exudate (4 h), as well as total and differential leukocytes and NO levels (48 h). Conclusions : Steroids, NO and ADA are implicated in the anti‐inflammatory action of PK11195.
Johansson crystals for x-ray diffractometry and demanding spectroscopy applications (2011)

Johansson crystals have been known for many decades as x-ray optical elements with a high resolving power and small foci. However, in the past their use in applications requiring a small focus and a narrow band pass were limited by imperfections caused by the technologies applied to their manufacture. While high performance Johansson crystals might have been achieved in some research facilities, such crystals were not commercially available. RIT has developed a process for fabricating precision Johansson crystals. The fabrication maintains the crystal structure intact. The angular precision of the bending process of atomic planes and the reflecting crystal surface is better than four arc seconds. In this paper, we will present the basic aspects of the technology and the achievements with Silicon and Germanium crystals.
Helicopter hub fairing and pylon interference drag (1989)

A wind tunnel test was conducted to study the aerodynamics of helicopter hub and pylon fairings. The test was conducted in the 7-by 10 Foot Subsonic Wind Tunnel (Number 2) at Ames Research Center using a 1/5-scale XH-59A fuselage model. The primary focus of the test was on the rotor hub fairing and pylon mutual interference drag. Parametric studies of pylon and hub fairing geometry were also conducted. This report presents the major findings of the test as well as tabulated force and moment data, flow visualization photographs, and graphical presentations of the drag data. The test results indicate that substantial drag reduction can be attained through the use of a cambered hub fairing with circular arc upper surface and flat lower surface. Furthermore, a considerable portion of the overall drag reduction is attributed to the reduction in the hub-on-pylon interference drag. It is also observed that the lower surface curvature of the fairing has a strong influence on the hub fairing and on pylon interference drag. However, the drag reduction benefit that was obtained by using the cambered hub fairing with a flat lower surface was adversely affected by the clearance between the hub fairing and the pylon.
The Airway Mechanics of Jet Ventilation (1981)

Jet venturi ventilation is frequently used in the airway management during microlaryngeal surgery. We have studied the relationships between the ventilating injector system and the lungs and outflow tract in a mechanical model. We found that tidal volume is directly proportional to system driving pressure, injector diameter, and lung compliance, and inversely proportional to airway resistance and outflow tract area.
Proteomics of regulated secretory organelles (2009)

Regulated secretory organelles are important subcellular structures of living cells that allow the release in the extracellular space of crucial compounds, such as hormones and neurotransmitters. Therefore, the regulation of biogenesis, trafficking, and exocytosis of regulated secretory organelles has been intensively studied during the last 30 years. However, due to the large number of different regulated secretory organelles, only a few of them have been specifically characterized. New insights into regulated secretory organelles open crucial perspectives for a better comprehension of the mechanisms that govern cell secretion. The combination of subcellular fractionation, protein separation, and mass spectrometry is also possible to study regulated secretory organelles at the proteome level. In this review, we present different strategies used to isolate regulated secretory organelles, separate their protein content, and identify the proteins by mass spectrometry. The biological significance of regulated secretory organelles-proteomic analysis is discussed as well.
Childhood anaplastic large cell lymphoma has a high incidence of <i>ALK</i> gene rearrangement as determined by immunohistochemical staining and fluorescent <i>in situ</i> hybridisation: a genetic and pathological correlation* (2005)

Anaplastic large cell lymphoma (ALCL) comprises 10-15% of childhood non-Hodgkin lymphomas (NHL). Systemic ALCL is highly associated with anaplastic lymphoma kinase (ALK) gene translocations with over-expression of ALK protein. We studied ALK rearrangements using fluorescence in situ hybridisation (FISH) and ALK immunohistochemical staining in 43 paediatric systemic ALCLs. FISH (performed on 35 cases) identified a translocation in 29 cases (83%). Immunohistochemistry identified ALK over-expression in 42/43 cases (97%) with the single ALK-negative case demonstrating an ALK rearrangement by FISH, indicating 100% incidence of ALK translocations.
The Cyclization of Ethyl Cyanoacetate and Salicylaldehyde or 3-Methoxysalicylaldehyde with Ketones by Means of Ammonium Acetate (1970)

Abstract Various substituted benz[f]isoquinolines were readily prepared by the condensation of ethyl cyanoacetate and salicylaldehyde or 3-methoxysalicylaldehyde with aliphatic ketones (acetone, diethyl ketone, methyl pentyl ketone, methyl isopentyl ketone, etc.) or aromatic ketones (acetophenone, o-hydroxyacetophenone, m-nitroacetophenone, propiophenone, etc.) in the presence of ammonium acetate. On the other hand, condensation with cyclic ketones such as cyclopentanone and cyclohexanone gave benz[f]cyclopent[c]isoquinolines and benzo[k]phenanthridines respectively.
Dual‐band water and lipid suppression for MR spectroscopic imaging at 3 Tesla (2010)

A dual-band water and lipid suppression sequence was developed for multislice sensitivity-encoded proton MR spectroscopic imaging of the human brain. The presaturation scheme consisted of five dual-band frequency-modulated radiofrequency pulses based on hypergeometric functions integrated with eight outer volume suppression (OVS) pulses. The flip angles of the dual-band pulses were optimized through computer simulations to maximize suppression factors over a range of transmitter amplitude of radiofrequency field and water and lipid T(1) values. The resulting hypergeometric dual band with OVS (HGDB + OVS) sequence was implemented at 3 T in a multislice sensitivity-encoded proton MR spectroscopic imaging experiment and compared to a conventional water suppression scheme (variable pulse power and optimized relaxation delays (VAPOR)) with OVS. The HGDB sequence was significantly shorter than the VAPOR sequence (230 versus 728 msec). Both HGDB + OVS and VAPOR + OVS produced good water suppression, while lipid suppression with the HGDB + OVS sequence was far superior. In sensitivity-encoded proton MR spectroscopic imaging data, artifacts from extracranial lipid signals were significantly lower with HGDB + OVS. The shorter duration of HGDB compared to VAPOR also allows reduced pulse repetition time values in the multislice acquisition.
Interaction of hydrophobized antiviral antibodies with influenza virus infected MDCK cells. (1993)

The ability of artificially stearoylated antibodies to influenza virus hemagglutinin and M1 proteins to interfere with influenza infection in MDCK cells has been studied. Both the modified anti-hemagglutinin (polyclonal) and anti-M1 (monoclonal) antibodies neutralize the virus when added before the infection. The effect can be attributed to the interaction of stearoylated antibodies with the virus surface, which is enhanced by fatty acylation (anti-hemagglutinin), or to the antibody uptake in the cell endocytic compartments simultaneously with the virion which permits antibodies to interact with the virus envelope internal antigen (anti-M1). The stearoylated antibodies to hemagglutinin inhibit the virus reproduction being added to the infected cells. This effect is believed to be due to the interaction of the antibodies with newly synthesized hemagglutinin on the cell surface which disturbs the virus budding and assemblage; fatty acylation intensifying this interaction.
Gene Expression and Release of Growth Factors During Delayed Wound Healing: A Review of Studies in Diabetic Animals and Possible Combined Laser Phototherapy and Growth Factor Treatment to Enhance Healing (2012)

Growth factor administration combined with laser irradiation may provide an effective therapy to maximize healing of diabetic wounds.
Studies of Cerebral Protective Agents. Preparation and Pharmacological Evaluation of 1-(1,4-Benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes as Potent Cerebral Protective Agents. (1996)

Two new series of 1-(1,4-benzoquinon-2-yl)-1,2,3,4-tetrahydronaphthalenes (3,4) were synthesized for evaluation of their pharmacological activities. These compounds showed significant anti-lipid peroxidation (ALP) activities with rat brain homogenate and some of them possessed a protective effect against hypobaric hypoxia in mice.
Treatment of acute anaphylaxis: Letters contained errors of logic (1996)

and two related to relief.Firstly, good information should be given to parents, schools, and children and should include the dangers of cannabis (memory impairment, the fact that it contains more carcinogens than tobacco, etc).Secondly, drugs should be eliminated.The police are on the right track in the way that they tackle big dealers, but they should be allowed to tackle street dealing as well, because it is difficult to find drugs when petty sales are reduced.'Thirdly, users should be able to gain admission to drug free institutions where they are treated with respect and encouragement so that they can regain their self respect.Finally, good aftercare is necessary: any former user should have a counsellor, who could help him or her find accommodation and a job.Weekly urine checks are advisable so that any relapse can be recognised.