gebhart/patrepeval huggingface dataset:
LINGUALIZED INTEGRATION: TOOTH MOLDS AND AN OCCLUSAL SCHEME FOR EDENTULOUS IMPLANT PATIENTS (1992)

The interface of bone and soft tissue to dental implants has been extensively documented, while the influence of biomechanics and the occlusal interface continues to be overlooked. Yet that same occlusal interface may ultimately be the prime factor in the lifetime survival rate of dental implants. What is lacking, for the practitioner, is a clear concept of the occlusal rehabilitation which is required and appropriate for the totally edentulous implant patient. Lingualized integration represents an occlusal scheme using specific tooth molds designed to improve the likelihood of maximum intercuspation and an absence of deflective occlusal contacts, provide cusp height for selective occlusal reshaping, and achieve a natural and pleasing appearance. Factors in the articulation and arrangement of the posterior teeth to assure the attainment of the fundamental goals of comfort, function, and appearance in occlusal rehabilitation for edentulous implant patients are included.
Graphene-Supported Silver Nanoparticles for pH-Neutral Electrocatalytic Oxygen Reduction (2014)

Developing an electrocatalyst with desired activity and affordable cost for oxygen reduction reaction (ORR) of microbial fuel cell (MFC) remains a key challenge for practical application of MFC in wastewater treatment. In order to find an economic replacement of Pt-based catalysts while maintaining comparable catalytic efficiency, an electrocatalyst of graphene-supported silver nanoparticles (AgNPs/rGO) was prepared via a facile coreduction and its activity toward ORR in pH-neutral MFC was examined. It has been demonstrated that one-pot aqueous coreduction yielded high-quality AgNPs/rGO catalyst, as revealed by X-ray diffraction and transmission electron microscope. Interestingly, the XPS profiles also indicated the presence of oxygen-containing groups on graphene surface, which provided nuclei to form AgNPs. The resultant AgNPs/rGO catalyst displayed good ORR catalytic activity under pH-neutral condition in cyclic voltammogram and its selectivity of four-electron reduction was verified by rotating disk electrode (RDE) measurement. Moreover, AgNPs/rGO could deliver power generation and sustainability comparable to those of commercial Pt/C in a double-chamber MFC. Thus, we have demonstrated, for the first time, that graphene sheets may provide an alternative way for preparation of Ag nanocomposite catalyst and AgNPs when loaded onto graphene surface can function as a promising replacement of Pt-based catalysts under pH-neutral condition. Since Ag is less expensive and more resistant to poisons than Pt, AgNPs/rGO has better potential to be applied to MFC for recovering energy during wastewater treatment.
Necrotizing lymphadenitis (1983)

Thirty patients with necrotizing lymph-adenitis, a disorder initially described in Japan and commonly misdiagnosed as malignant lymphoma, have been studied, in addition, stains for immunologic markers were performed. The patients included 21 United States residents and most commonly were young women with a subacute illness characterized by persistent, painless cervical adenopathy with or without fever. The excised lymph nodes were moderately enlarged and typically showed focal, well-circumscribed, paracortical, necrotizing lesions, and abundant karyorrhectic debris, scattered fibrin deposits, aggregates of large mononuclear cells, and a paucity of plasma cells and neutrophils. Immunohistochemical stains on frozen tissue sections were positive for 63D3 and Leu-2a, indicating an admixture of of histiocytes/macrophages and cytotoxic/suppressor T-lymphocytes in the necrotizing lesions. The etiology of necrotizing lymphadenitis and its distinction from other causes of reactive lymphadenitis are discussed. To our knowledge, this disorder has not previously been reported in the United States.
Selectively formed AlAs/InP current confining tunnel junction for GaInAsP/InP surface emitting lasers (2003)

We propose a novel current injection and confinement structure which can be fabricated by thermal annealing of a metal electrode to selectively destroy an AlAs/InP tunnel junction. The destroyed tunnel junction becomes a high-resistance isolation layer and the hole current can be supplied through a preserved tunnel junction window. We confirmed its current blocking and lateral confinement effect from the near field pattern of fabricated GaInAsP/InP stripe lasers. The secondary ion mass spectroscopy (SIMS) measurement showed that this current confinement structure was formed by migration of electrode metal into the tunnel junction. The proposed scheme is being applied to the lateral current injection structure in long-wavelength vertical cavity surface emitting lasers (VCSELs).
Isolated high-harmonics pulse from two-color-driven bloch oscillations in bulk semiconductors (2012)

The time-frequency characteristics of high-order harmonic generation (HHG) from Bloch-oscillating electrons in bulk ZnO crystals are investigated. Spectrally filtering out the Bloch-HHG cutoff radiation allows the generation of an isolated Bloch-HHG pulse of ~1.6-fs duration.
ENHANCED PRACTICAL PHOTOSYNTHETIC CO2 MITIGATION (2001)

This quarterly report documents significant achievements in the Enhanced Practical Photosynthetic CO{sub 2} Mitigation project during the period from 1/03/2001 through 4/02/2001. Many of the activities and accomplishments are continuations of work initiated and reported in last quarter's status report. Major activities and accomplishments for this quarter include: Three sites in Yellowstone National Park have been identified that may contain suitable organisms for use in a bioreactor; Full-scale culturing of one thermophilic organism from Yellowstone has progressed to the point that there is a sufficient quantity to test this organism in the model-scale bioreactor; The effects of the additive monoethanolamine on the growth of one thermophilic organism from Yellowstone has been tested; Testing of growth surface adhesion and properties is continuing; Construction of a larger model-scale bioreactor to improve and expand testing capabilities is completed and the facility is undergoing proof tests; Model-scale bioreactor tests examining the effects of CO{sub 2} concentration levels and lighting levels on organism growth rates are continuing; Alternative fiber optic based deep-penetration light delivery systems for use in the pilot-scale bioreactor have been designed, constructed and tested; An existing slug flow reactor system has been modified for use in this project, and a proof-of-concept test plan has been developed for the slug flow reactor; Research and testing of water-jet harvesting techniques is continuing, and a harvesting system has been designed for use in the model-scale bioreactor; and The investigation of comparative digital image analysis as a means for determining the ''density'' of algae on a growth surface is continuing Plans for next quarter's work and an update on the project's web page are included in the conclusions.
Integrin traffic – the update (2015)

Integrins are a family of transmembrane cell surface molecules that constitute the principal adhesion receptors for the extracellular matrix (ECM) and are indispensable for the existence of multicellular organisms. In vertebrates, 24 different integrin heterodimers exist with differing substrate specificity and tissue expression. Integrin-extracellular-ligand interaction provides a physical anchor for the cell and triggers a vast array of intracellular signalling events that determine cell fate. Dynamic remodelling of adhesions, through rapid endocytic and exocytic trafficking of integrin receptors, is an important mechanism employed by cells to regulate integrin-ECM interactions, and thus cellular signalling, during processes such as cell migration, invasion and cytokinesis. The initial concept of integrin traffic as a means to translocate adhesion receptors within the cell has now been expanded with the growing appreciation that traffic is intimately linked to the cell signalling apparatus. Furthermore, endosomal pathways are emerging as crucial regulators of integrin stability and expression in cells. Thus, integrin traffic is relevant in a number of pathological conditions, especially in cancer. Nearly a decade ago we wrote a Commentary in Journal of Cell Science entitled 'Integrin traffic'. With the advances in the field, we felt it would be appropriate to provide the growing number of researchers interested in integrin traffic with an update.
Deposition of Fluorocarbon Films on Al and SiO <sub>2</sub> Surfaces in High‐Density Fluorocarbon Plasmas: Selectivity and Surface Wettability (2005)

This chapter contains sections titled: Introduction Experimental Results and Discussion Etching and Deposition in C4F8 Plasmas Etching and Deposition Experiments in CHF3/CH4 Plasmas FC Film Characterization: Chemical Composition Conclusions
Entorno familiar y angustia psicológica en personas deficientes visuales (1996)

En este estudio se investiga la relacion entre el entorno familiar y la angustia psicologica percibida en 76 personas deficientes visuales, con edades comprendidas entre los 18 y 94 anos, que siguieron cursos de rehabilitacion durante un minimo de cuatro meses. Los resultados indicaron que las caracteristicas del entorno familiar ejercian una enorme influencia en la adaptacion de estas personas a la perdida de la vision.
Jornalismo Literário: análise de reportagens de José Hamilton Ribeiro na revista Realidade (2013)

Este artigo busca identificar as características do jornalismo literário em reportagens produzidas pelo jornalista José Hamilton Ribeiro para a revista Realidade no seu primeiro ano de existência. Para isso, analisa três reportagens publicadas no período correspondente da publicação. Como base teórica utilizou-se uma revisão bibliográfica sobre literatura, jornalismo, jornalismo literário e o seu surgimento tendo como referências autores como Felipe Pena, Vitor Necchi, Sergio Vilas Boas. Além disso, o artigo trás conceitos, características do jornalismo literário, para então fazer a análise das reportagens. Do ponto de vista metodológico foi usada a análise de texto para esmiuçar o conteúdo e a identificação das características do jornalismo literário nas reportagens analisadas. E chega à conclusão que há traços de características de jornalismo literário nas reportagens estudadas
Performance evaluation and design trade-offs for wireless network-on-chip architectures (2012)

Massive levels of integration are making modern multicore chips all pervasive in several domains. High performance, robustness, and energy-efficiency are crucial for the widespread adoption of such platforms. Networks-on-Chip (NoCs) have emerged as communication backbones to enable a high degree of integration in multicore Systems-on-Chip (SoCs). Despite their advantages, an important performance limitation in traditional NoCs arises from planar metal interconnect-based multihop links with high latency and power consumption. This limitation can be addressed by drawing inspiration from the evolution of natural complex networks, which offer great performance-cost trade-offs. Analogous with many natural complex systems, future multicore chips are expected to be hierarchical and heterogeneous in nature as well. In this article we undertake a detailed performance evaluation for hierarchical small-world NoC architectures where the long-range communications links are established through the millimeter-wave wireless communication channels. Through architecture-space exploration in conjunction with novel power-efficient on-chip wireless link design, we demonstrate that it is possible to improve performance of conventional NoC architectures significantly without incurring high area overhead.
Development of Inhibitors Targeting Hypoxia-Inducible Factor 1 and 2 for Cancer Therapy (2017)

Hypoxia is frequently observed in solid tumors and also one of the major obstacles for effective cancer therapies. Cancer cells take advantage of their ability to adapt hypoxia to initiate a special transcriptional program that renders them more aggressive biological behaviors. Hypoxia-inducible factors (HIFs) are the key factors that control hypoxia-inducible pathways by regulating the expression of a vast array of genes involved in cancer progression and treatment resistance. HIFs, mainly HIF-1 and -2, have become potential targets for developing novel cancer therapeutics. This article reviews the updated information in tumor HIF pathways, particularly recent advances in the development of HIF inhibitors. These inhibitors interfere with mRNA expression, protein synthesis, protein degradation and dimerization, DNA binding and transcriptional activity of HIF-1 and -2, or both. Despite efforts in the past two decades, no agents directly inhibiting HIFs have been approved for treating cancer patients. By analyzing results of the published reports, we put the perspectives at the end of the article. The therapeutic efficacy of HIF inhibitors may be improved if more efforts are devoted on developing agents that are able to simultaneously target HIF-1 and -2, increasing the penetrating capacity of HIF inhibitors, and selecting suitable patient subpopulations for clinical trials.
Probing neutralizing-antibody responses against emerging measles viruses (MVs): immune selection of MV by H protein-specific antibodies? (2005)

Measles virus (MV) infection and vaccination induce long-lasting immunity and neutralizing-antibody responses that are directed against the MV haemagglutinin (H) and the fusion (F) protein. A new MV genotype, D7, emerged recently in western Germany and rapidly replaced the long-term endemically circulating genotypes C2 and D6. Analysis of the H gene of C2, D6, D7 and vaccine viruses revealed uniform sequences for each genotype. Interestingly, a consistent exchange of seven distinct amino acids in the D7 H was observed when compared with residues shared between C2, D6 and vaccine viruses, and one exchange (D416-->N) in the D7 H was associated with an additional N-linked glycosylation. In contrast, the F gene is highly conserved between MVs of these genotypes. To test whether the D7 H protein escapes from antibody responses that were raised against earlier circulating or vaccine viruses, the neutralizing capacity of mAbs recognizing seven distinct domains on the H of an Edmonston-related MV was compared. The mAbs revealed a selective and complete loss of two neutralizing epitopes on the D7 H when compared with C2, D6 and vaccine viruses. To assess whether these alterations of the D7 H affect the neutralizing capacity of polyclonal B-cell responses, genotype-specific antisera were produced in cotton rats. However, no significant genotype-dependent difference was found. Likewise, human sera obtained from vaccinees (n=7) and convalescents (n=6) did not distinguish between the MV genotypes. Although the hypothesis of selection of D7 viruses by pre-existing neutralizing antibodies is compatible with the differing pattern of neutralizing epitopes on the H protein, it was not confirmed by the results of MV neutralization with polyclonal sera.
A survey of inter-vehicle communication protocols and their applications (2009)

Inter-vehicle communication (IVC) protocols have the potential to increase the safety, efficiency, and convenience of transportation systems involving planes, trains, automobiles, and robots. The applications targeted include peer-to-peer networks for web surfing, coordinated braking, runway incursion prevention, adaptive traffic control, vehicle formations, and many others. The diversity of the applications and their potential communication protocols has challenged a systematic literature survey. We apply a classification technique to IVC applications to provide a taxonomy for detailed study of their communication requirements. The applications are divided into type classes which share common communication organization and performance requirements. IVC protocols are surveyed separately and their fundamental characteristics are revealed. The protocol characteristics are then used to determine the relevance of specific protocols to specific types of IVC applications.
Structural and ferroelectric properties of r.f. magnetron sputtered SrBi/sub 2/Ta/sub 2/O/sub 9/ thin films (2002)

Radio-frequency magnetron sputtering was used to deposit SrBi/sub 2/Ta/sub 2/O/sub 9/ ferroelectric thin films on Pt(111)/Ti/SiO/sub 2//Si(100) substrates with 15% Bi/sub 2/O/sub 3/ excess SrBi/sub 2/Ta/sub 2/O/sub 9/ ceramic target. Thin films were deposited at room temperature with argon pressures of 0.5/spl sim/100 mTorr and sputtering power of 200 W. Deposited thin films were post-annealed at 800/spl deg/C for 2 hours in O/sub 2/ atmosphere. Structural properties were investigated with X-ray diffraction techniques. And microstructures were observed by the scanning electron microscope. Crystal orientations and microstructures of the thin films were strongly affected by the argon pressures during the deposition. Ferroelectric properties of the Pt/SrBi/sub 2/Ta/sub 2/O/sub 9//Pt capacitors were obtained. The physical properties of the c-axis oriented and polycrystalline SrBi/sub 2/Ta/sub 2/O/sub 9/ were compared. The c-axis oriented thin films show good ferroelectric properties, (P*/sub r/-P/sup /spl circ///sub r/) and E/sub c/ were 10.4 /spl mu/C/cm/sup 2/ and 50 kV/cm, respectively. And for the polycrystalline thin film, (P*/sub r/-P/sup /spl circ///sub r/) and E/sub c/ were 6.5 /spl mu/C/cm/sup 2/ and 43 kV/cm, respectively.
Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes (2010)

Erythrocytes release ATP in response to exposure to the physiological stimulus of lowered oxygen (O(2)) tension as well as pharmacological activation of the prostacyclin receptor (IPR). ATP release in response to these stimuli requires activation of adenylyl cyclase, accumulation of cAMP, and activation of protein kinase A. The mechanism by which ATP, a highly charged anion, exits the erythrocyte in response to lowered O(2) tension or receptor-mediated IPR activation by iloprost is unknown. It was demonstrated previously that inhibiting pannexin 1 with carbenoxolone inhibits hypotonically induced ATP release from human erythrocytes. Here we demonstrate that three structurally dissimilar compounds known to inhibit pannexin 1 prevent ATP release in response to lowered O(2) tension but not to iloprost-induced ATP release. These results suggest that pannexin 1 is the conduit for ATP release from erythrocytes in response to lowered O(2) tension. However, the identity of the conduit for iloprost-induced ATP release remains unknown.
A multiresolution 100-GOPS 4-Gpixels/s programmable smart vision sensor for multisense imaging (2005)

This paper presents a multiresolution general-purpose high-speed machine vision sensor with on-chip image processing capabilities. The sensor comprises an innovative multiresolution sensing area, 1536 A/D converters, and a SIMD array of 1536 bit-serial processors with corresponding memory. The sensing area consists of an area part with 1536 /spl times/ 512 pixels, and a line-scan part with a set of rows with 3072 pixels each. The SIMD processor array can deliver more than 100 GOPS sustained and the on-chip pixel-analysing rate can be as high as 4Gpixels/s. The sensor is ideal for high-speed multisense imaging where, e.g., color, greyscale, internal material light scatter, and 3-D profiles are captured simultaneously. When running only 3-D laser triangulation, a data rate of more than 20 000 profiles/s can be achieved when delivering 1536 range values per profile with 8 bits of range resolution. Experimental results showing very good image characteristics and a good digital to analog noise isolation are presented.
Integrated Genetic Analysis Microsystems (2005)

The advent of integrated microsystems for genetic analysis allows the acquisition of information at unprecedented length and time scales. The convergence of molecular biology, chemistry, physics, and materials science is required for their design and construction. The utility of the microsystems originates from increased analysis speed, lower analysis cost, and higher parallelism leading to increased assay throughput. In addition, when fully integrated, this technology will enable portable systems for high-speed in situ analyses, permitting a new standard in disciplines such as clinical chemistry, personalized medicine, forensics, biowarfare detection, and epidemiology. This article presents an overview of the recent history of integrated genetic analysis microsystems with an emphasis on materials aspects, and provides a perspective on current developments and future prospects. Keywords: microfabricationgeneticsintegrationanalysisreview ACKNOWLEDGMENTS The authors thank Professors M. A. Burns, A. Manz, R. A. Mathies, and K. W. Plaxco for their permission to reprint figures from their publications here.
Design and evaluation of single nozzle with a non-conductive tip for reducing applied voltage and pattern width in electrohydrodynamic jet printing (EHDP) (2010)

We investigated the effect of a non-conductive tip inserted into a capillary nozzle (inner diameter of 860 µm) on jet formation and pattern width in electrohydrodynamic jet printing. Simulated and experimental results showed that the non-conductive tip stabilized the jet, and reduced the effective nozzle diameter and the onset voltage needed for the cone-jet mode, by eliminating the backflow near the apex of the liquid cone while a tiny backflow away from the apex of the liquid cone still remained. Silver nanocolloid patterns with an average width of 18.5 µm (standard deviation: 1.5 µm) were obtained with an applied voltage of 2.7 kV, a flow rate of 3 µl min−1 and a stage velocity of 200 mm s−1.
Versuche im Enamingebiet, VII. Reaktionen von Arylsulfonylaziden mit Enaminen aus Ketomethylenverbindungen (1963)

Abstract Die Umsetzung von Enaminen aus Ketomethylenverbindungen mit Arylsulfonylaziden folgt, je nach dem Substitutionstyp, unterschiedlichen Reaktionsschemata, die beschrieben und erörtert werden.
The social life of engineering authorizations (2000)

We may view documents, not only as containers for information, but also as active participants in organizing and sustaining communities. This paper discusses our experiences in designing a web-based tool for writing and managing engineering authorizations, and the social perspectives influence on our understanding of the problem and the design of our system. It presents observations based on our fieldwork with users, and the evaluation of a set of prototype systems. It shows how these observations changed our central metaphor for the system, moving it from a machine model to a society of agents metaphor. Finally, it illustrates the way this new metaphor changed our system functionality and architecture.
Rapid Typing of <i>Bordetella pertussis</i> Pertussis Toxin Gene Variants by LightCycler Real-Time PCR and Fluorescence Resonance Energy Transfer Hybridization Probe Melting Curve Analysis (2002)

A LightCycler real-time PCR hybridization probe assay was developed for rapid typing of gene variants of the Bordetella pertussis virulence factor pertussis toxin. The assay correctly identified the ptxS1 alleles of all strains tested, comprising 57 Finnish clinical isolates and 2 vaccine strains. The method is simple, reliable, and suitable for large-scale screening of B. pertussis strains.