gebhart/patrepeval huggingface dataset:
Convolutional neural networks with intra-layer recurrent connections for scene labeling (2015)

Scene labeling is a challenging computer vision task. It requires the use of both local discriminative features and global context information. We adopt a deep recurrent convolutional neural network (RCNN) for this task, which is originally proposed for object recognition. Different from traditional convolutional neural networks (CNN), this model has intra-layer recurrent connections in the convolutional layers. Therefore each convolutional layer becomes a two-dimensional recurrent neural network. The units receive constant feed-forward inputs from the previous layer and recurrent inputs from their neighborhoods. While recurrent iterations proceed, the region of context captured by each unit expands. In this way, feature extraction and context modulation are seamlessly integrated, which is different from typical methods that entail separate modules for the two steps. To further utilize the context, a multi-scale RCNN is proposed. Over two benchmark datasets, Standford Background and Sift Flow, the model outperforms many state-of-the-art models in accuracy and efficiency.
Self-Wrinkling Patterned Surface of Photocuring Coating Induced by the Fluorinated POSS Containing Thiol Groups (F-POSS-SH) as the Reactive Nanoadditive (2012)

We here demonstrate a facile approach of one-step to obtain the complex wrinkling patterned surface of the photocuring coating by using thiol and fluorocarbon chains containing POSS (F2-POSS-SH6) as reactive nanoadditive. F2-POSS-SH6 can self-assemble into the top layer of the UV-curing liquid resin. As a result, the mismatch of shrinkage caused by the different types of photo-cross-linking reaction between the top layer and bulk layer leads to formation of the wrinkling pattern. The characteristic wavelength (λ) and amplitude (A) are linearly dependent on the concentration of F2-POSS-SH6. The resulting surface exhibits superlow surface energy (4.1 mN/m) when the concentration of F2-POSS-SH6 is only 1%. The feasibility and generality of this approach for the excellent hydrophobic and oleophobic surface will undoubtedly find practical application in photocuring coating with functions such as self-cleaning.
O bibliotecário e a sociedade da informação 10.5007/1518-2924.2001v6n12p45 (2007)

Reflections on the role of the librarian in the information society. Introduce the dilemas of this profession in the globalized world. Present the possibilities and the challenges to be faced by librarians in modern times.
Dysthymia and serotonin (1993)

Institute of Mental Health Research, Royal Ottawa Hospital, 1145 Carling Avenue, Otfowa, Ontario, Canada K1Z 7K4
Genetic Toxicity of Several Antihypertensive Drugs Possessing a Hydrazine Group (1986)

Mutagenicity and genotoxicity of antihypertensive drugs, ecarazine, budralazine, benzerazide, and carbidopa were compared with those of hydralazine whose genetic toxicity and carcinogenicity were well established. Ecarazine and budralazine as well as hydralazine showed apparent mutagenicity in Salmonella/microsome test using a strain TA 100 and weak mutagenicity in strains TA 97 and 2637. Benzerazide and carbidopa showed merely weak mutagenicity in TA 100. None of tested drugs except hydralazine exerted any positive result in hepatocyte primary culture (HPC)/DNA repair test, indicating no genotoxic activity of these hydrazine drugs.
Aqueous biphasic systems: a boost brought about by using ionic liquids (2012)

During the past decade, ionic-liquid-based Aqueous Biphasic Systems (ABS) have been the focus of a significant amount of research. Based on a compilation and analysis of the data hitherto reported, this critical review provides a judicious assessment of the available literature on the subject. We evaluate the quality of the data and establish the main drawbacks found in the literature. We discuss the main issues which govern the phase behaviour of ionic-liquid-based ABS, and we highlight future challenges to the field. In particular, the effect of the ionic liquid structure and the various types of salting-out agents (inorganic or organic salts, amino acids and carbohydrates) on the phase equilibria of ABS is discussed, as well as the influence of secondary parameters such as temperature and pH. More recent approaches using ionic liquids as additives or as replacements for common salts in polymer-based ABS are also presented and discussed to emphasize the expanding number of aqueous two-phase systems that can actually be obtained. Finally, we address two of the main applications of ionic liquid-based ABS: extraction of biomolecules and other added-value compounds, and their use as alternative approaches for removing and recovering ionic liquids from aqueous media.
Morphological enhancement of coronary angiograms (2002)

Two ways of applying morphological image processing techniques (MORPH) to cardiac angiography images are identified. First, arterial contrast can be selectively increased using contrast-containing images alone. Second, MORPH can be used as a preprocessing step to preflatten both the contrast and mask images prior to subtraction. This procedure, called MORPH-DSA, removes most of the gray-scale changes due to the beating of the heart. This reduces subtraction artifacts and allows a sequence of subtracted images to be displayed with a narrower gray-scale window-width than that following normal DSA processing.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Attenuation of half-tone background detail from fingermark images using digital image processing techniques (2002)

Frequency domain processing of fingermark images is valuable for reducing interfering periodic backgrounds. The success of the processing and the quality of the results depend upon a number of factors including structure and chosen processing method. This paper shows that in some circumstances it is possible to determine the most appropriate frequency domain filter for attenuation of interfering backgrounds using automatic computer based generation of frequency domain filters. Success has been achieved with half-tone printed backgrounds.
Three-Dimensional Geophysical Characterization of Deeply Buried Paleokarst System in the Tahe Oilfield, Tarim Basin, China (2019)

Paleokarst reservoirs are the major type of the Ordovician carbonate reservoirs in the Tahe Oilfield. Due to the strong heterogeneity in distribution, it is a real challenge to detect the spatial distribution of paleokarst reservoirs, especially those deeply buried more than 5500 m in the Tahe area. Based on the abundant core samples, this paper first described the structure of paleocaves drilled by well. Second, after time–depth conversions, the results from drilled wells were tied to three-dimensional (3D) seismic datasets, and then the threshold of host rocks and caves in wave impedance were identified. Third, the seismic-scale mapping and visualization of the paleokarst reservoirs were achieved by tracing the distribution of paleocaves. This approach was applied in the well T403 area, and the structure of the paleokarst, especially the runoff zone, was interpreted. 3D structure and spatial distribution of the paleokarst system was demonstrated by plane, vertical, and 3D models. Additionally, according to the hydrology genetic relationships, the paleocaves in the runoff zone were divided into sinkholes, main channel, and branch channel. The approach of a 3D geophysical characterization of a deeply buried paleokarst system can be applicable to Tahe and other similar paleokarst oilfields, which will guide hydrocarbon exploration in paleokarst reservoirs.
Metric structure from motion by indoor localization using Wi-Fi channel state information (2017)

3D reconstruction methods for real-world environments based on camera images have recently been studied by many researchers and structure from motion (SFM) has been attracting attention as one of the most practical approaches for 3D reconstruction. SFM can estimate relative positions of cameras using many camera images and then reconstruct a 3D scene of the environment based on the positions. However, because the distances between cameras estimated by SFM have scale ambiguity, the scale ambiguity remains also in the reconstructed 3D scene. In this study, we propose a method for reconstructing a 3D scene with real-world scale in an indoor environment by estimating the absolute coordinates of cameras based on an indoor localization technique using Wi-Fi channel state information (CSI).
Snap Cards (1916)

Snap Cards Get access Night Work Night Work Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s12-II, Issue 37, 9 September 1916, Page 210, https://doi.org/10.1093/nq/s12-II.37.210a Published: 09 September 1916
A group-based inference approach to customized marketing on the Web integrating clustering and association rules techniques (2005)

Because of the intelligent computing specialty of the World Wide Web, extensive customized marketing can be executed at much lower cost and has become an emerging research issue. Therefore, the first purpose of this paper is to propose a system framework to serve as a foundation for developing a customized marketing system on the Web according to the discussions on data sources, data categories, and inference foundations. Most previous studies used induction-learning techniques to perform individual-based inference for customized marketing. However, it not only costs more to learn the personal preferences, but also some difficulties occur from using induction-learning techniques. The second purpose of this paper is to solve these problems. A group-based approach that integrates clustering and association rules is proposed. We conducted a field study to collect data to demonstrate the proposed group-based inference approach and evaluate its performance. The results reveal that this integrated approach can learn both more detailed and precise rules.
Persistent Mitochondrial Hyperpolarization, Increased Reactive Oxygen Intermediate Production, and Cytoplasmic Alkalinization Characterize Altered IL-10 Signaling in Patients with Systemic Lupus Erythematosus (2002)

Abnormal death signaling in lymphocytes of systemic lupus erythematosus (SLE) patients has been associated with elevation of the mitochondrial transmembrane potential (Delta psi(m)) and increased production of reactive oxygen intermediates (ROI). The resultant ATP depletion sensitizes T cells for necrosis that may significantly contribute to inflammation in patients with SLE. In the present study, the role of mitochondrial signal processing in T cell activation was investigated. CD3/CD28 costimulation of PBL elicited transient mitochondrial hyperpolarization and intracellular pH (pH(i)) elevation, followed by increased ROI production. Baseline Delta psi(m), ROI production, and pH(i) were elevated, while T cell activation-induced changes were blunted in 15 patients with SLE in comparison with 10 healthy donors and 10 rheumatoid arthritis patients. Similar to CD3/CD28 costimulation, treatment of control PBL with IL-3, IL-10, TGF-beta(1), and IFN-gamma led to transient Delta psi(m) elevation. IL-10 had diametrically opposing effects on mitochondrial signaling in lupus and control donors. Unlike healthy or rheumatoid arthritis PBL, cells of lupus patients were resistant to IL-10-induced mitochondrial hyperpolarization. By contrast, IL-10 enhanced ROI production and cell death in lupus PBL without affecting ROI levels and survival of control PBL. Ab-mediated IL-10 blockade or stimulation with antagonistic lymphokine IL-12 normalized baseline and CD3/CD28-induced changes in ROI production and pH(i) with no impact on Delta psi(m) of lupus PBL. The results suggest that mitochondrial hyperpolarization, increased ROI production, and cytoplasmic alkalinization play crucial roles in altered IL-10 responsiveness in SLE.
Deadbeat Predictive Current Control of Permanent-Magnet Synchronous Motors with Stator Current and Disturbance Observer (2016)

In order to optimize the current-control performance of the permanent-magnet synchronous motor (PMSM) system with model parameter mismatch and one-step control delay, an improved deadbeat predictive current control (DPCC) algorithm for the PMSM drive systems is proposed in this paper. First, the performance of the conventional predictive current control, when parameter mismatch exist, is analyzed, and then a stator current and disturbance observer (SCDO) based on sliding-mode exponential reaching law, which is able to simultaneously predict future value of stator current and track system disturbance caused by parameter mismatch in real time, is proposed. Based on this SCDO, prediction currents are used for replacing the sampled current in DPCC to compensate one-step delay, and estimated parameter disturbances are considered as the feedforward value to compensate the voltage reference calculated by deadbeat predictive current controller. Thus, a composite control method combining the DPCC part and current prediction and feedforward compensation part based on SCDO, called DPCC + SCDO method, is developed. Moreover, based on conventional exponential reaching law, a novel sliding-mode exponential reaching law is proposed to further improve the performance of the DPCC + SCDO method. Simulation and experimental results both show the validity of the proposed current control approach.
Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene. (1985)

The structural gene for yeast DNA topoisomerase I (TOP1) has been cloned from two yeast genomic plasmid banks. Integration of a plasmid carrying the gene into the chromosome and subsequent genetic mapping shows that TOP1 is identical to the gene previously called MAK1. Seven top1 (mak1) mutants including gene disruptions are viable, demonstrating that DNA topoisomerase I is not essential for viability in yeast. A 3787-base-pair DNA fragment including the gene has been sequenced. The protein predicted from the DNA sequence has 769 amino acids and a molecular weight of 90,020.
New players in the 5-HT receptor field: genes and knockouts (1995)

In recent years, cloning has revealed the existence of no less than 14 mammalian 5-HT receptors, as well as evidence that isoforms of the 5-HT4 and 5-HT7 receptors are generated by alternative splicing. In addition, molecular biology techniques have provided new tools with which to study the function of 5-HT receptors. For example, new technologies are emerging that will allow the generation of either inducible or tissue-specific knockouts (or both). In this review José Lucas and René Hen focus on the characteristics of the most recently cloned receptors and the contribution of molecular biology to the understanding of 5-HT receptor function.
Hologram display model (2003)

A so called hologram is a fully autostereoscopic 3D color display offering up to 128 depth level in front of and behind the display screen itself. These new display features will be achieved by an arrangement of lenticular glasses, color and brightness filters and a binary liquid crystal display being writable by laser beams and being erasable by electrical fields. The LC-layer can be substituted by a cheap image-coded black/white film showing a 3D-photo. A first model of a 20/spl times/16 inch 3D colour picture is presented.
<i>In situ</i> mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics (2013)

Current assays for somatic mutation analysis are based on extracts from tissue sections that often contain morphologically heterogeneous neoplastic regions with variable contents of normal stromal and inflammatory cells, obscuring the results of the assays. We have developed an RNA-based in situ mutation assay that targets oncogenic mutations in a multiplex fashion that resolves the heterogeneity of the tissue sample. Activating oncogenic mutations are targets for a new generation of cancer drugs. For anti-EGFR therapy prediction, we demonstrate reliable in situ detection of KRAS mutations in codon 12 and 13 in colon and lung cancers in three different types of routinely processed tissue materials. High-throughput screening of KRAS mutation status was successfully performed on a tissue microarray. Moreover, we show how the patterns of expressed mutated and wild-type alleles can be studied in situ in tumors with complex combinations of mutated EGFR, KRAS and TP53. This in situ method holds great promise as a tool to investigate the role of somatic mutations during tumor progression and for prediction of response to targeted therapy.
AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines (2006)

These data suggest that poly Q encoding region of AIB1 gene is somatic unstable in breast cancer cell lines. The instability and the sequence characteristics, however, do not appear to be associated with the level of the gene amplification.
Autophagy Control by the VEGF-C/NRP-2 Axis in Cancer and Its Implication for Treatment Resistance (2012)

A major contributor to cancer mortality is recurrence and subsequent metastatic transformation following therapeutic intervention. Therefore, in order to develop new treatment modalities and improve the efficacy of current ones, it is important to understand the molecular mechanisms that promote resistance to therapy in cancer cells. One pathway contributing to therapy resistance is autophagy, a self-digestive process that can eliminate unnecessary or damaged organelles to protect cancer cells from death. We have found that the VEGF-C/NRP-2 axis is involved in the activation of autophagy, which helps cancer cell survival following treatment. Inhibition of mTOR complex 1 activity by this axis is the underlying mechanism for the activation of autophagy. Furthermore, we identified two VEGF-C/NRP-2-regulated genes, LAMP-2 and WDFY-1, that have previously been suggested to participate in autophagy and vesicular trafficking. Upregulation of WDFY-1 following VEGF-C or NRP-2 depletion contributes to cytotoxic drug-mediated cell death. Together, these data suggest a link between the VEGF-C/NRP-2 axis and cancer cell survival despite the presence of chemotherapy-induced stress. Effective targeting of this pathway may lead to the development of new cancer therapies.
Histone Deacetylase Complex1 Expression Level Titrates Plant Growth and Abscisic Acid Sensitivity in <i>Arabidopsis</i>     (2013)

Histone deacetylation regulates gene expression during plant stress responses and is therefore an interesting target for epigenetic manipulation of stress sensitivity in plants. Unfortunately, overexpression of the core enzymes (histone deacetylases [HDACs]) has either been ineffective or has caused pleiotropic morphological abnormalities. In yeast and mammals, HDACs operate within multiprotein complexes. Searching for putative components of plant HDAC complexes, we identified a gene with partial homology to a functionally uncharacterized member of the yeast complex, which we called Histone Deacetylation Complex1 (HDC1). HDC1 is encoded by a single-copy gene in the genomes of model plants and crops and therefore presents an attractive target for biotechnology. Here, we present a functional characterization of HDC1 in Arabidopsis thaliana. We show that HDC1 is a ubiquitously expressed nuclear protein that interacts with at least two deacetylases (HDA6 and HDA19), promotes histone deacetylation, and attenuates derepression of genes under water stress. The fast-growing HDC1-overexpressing plants outperformed wild-type plants not only on well-watered soil but also when water supply was reduced. Our findings identify HDC1 as a rate-limiting component of the histone deacetylation machinery and as an attractive tool for increasing germination rate and biomass production of plants.
2 GHz Meißner VCO in Si Bipolar Technology (1999)

A completely integrated 2 0Hz Meißner VCO in silicon bipolar for wireless communications is presented. The chip is implemented in a 25GHz fT, 0.8μm, 3-layer-interconnect silicon bipolar production technology B6HF. The Meißner type oscillator circuit uses on-chip multiple coupled inductors and achieves a phase noise of -102dBc/Hz at an offset of l00kHz. The VCO is designed for 3V to 5V battery operation and delivers μ8.7 dBm of output power. The VCO meets the specifications for DECT cordless telephone sets.
Growth of human diploid fibroblasts in media with different amino acid composition (1974)

ABSTRACT Human embryonic diploid lung fibroblasts were capable of growing in a medium consisting of Eagle’s MEM vitamins plus 0·1 μg/ml biotin, Earle’s salt solution, 4 mM glutamine, 0·4 mM cystine, 0·5 mM tyrosine, 10 % undialysed calf serum and 1 mM pyruvate. The growth rate and percent cell attachment in this medium was slightly less than in Eagle’s MEM but the longevity was about the same. Addition of 0· 5–1·0 mM histidine stimulated growth but addition of 0· 2 mM phenylalanine, methionine or valine decreased longevity markedly. Maintaining a constant pH of about 7·5–7·6 with 20 mM of the organic buffers HEPES, TES or TRICINE yielded a growth rate equal to or better than that of cells growing in unbuffered medium. Some buffers gave good growth initially but eventually the longevity decreased (20mM BIS-TRIS, 20 mM BICINE, 10 mM TRIS). In almost all cases the initial exposure to the buffers yielded the best growth results.
The Effect of Anaerobiosis on Antistaphylococcal Antibiotics (1988)

The activity of eight antimicrobial agents which might be used in the treatment of staphylococcal osteomyelitis was tested under anaerobic conditions similar to those found in chronically infected bone. An agar-dilution method was employed to determine the minimum inhibitory concentrations of tobramycin, vancomycin, teicoplanin, ciprofloxacin, clindamycin, ceftriaxone, ticarcillin-clavulanic acid, and amoxicillin-clavulanic acid against 25 coagulase-positive and 25 coagulase-negative staphylococcal strains. The activity of tobramycin against coagulase-positive staphylococci, and of amoxicillin-clavulanic acid and ticarcillin-clavulanic acid against coagulase-negative staphylococci was markedly decreased with anaerobiosis. Vancomycin, teicoplanin, and ciprofloxacin were active against coagulase-positive and coagulase-negative staphylococci under both aerobic and anaerobic conditions. It was also found that antibiotic concentrations comparable to the high levels which might be achieved with local antibiotic therapy of osteomyelitis were not sufficient to overcome the level of resistance (100 micrograms/ml) of staphylococci which were not susceptible to tobramycin, clindamycin, ceftriaxone, and ticarcillin-clavulanic acid.
The Use of Spiked Plastic Washers in the Repair of Avulsed Ligaments (1981)

This paper illustrates the use of spiked plastic washers and A.O. compression screws in the repair of ligaments which have been avulsed from their bony origins. The technique is simple and some examples are described.