gebhart/patrepeval huggingface dataset:
Reconfigurable group robots adaptively transforming a mechanical structure - numerical expression of criteria for structural transformation and automatic motion planning method - (2007)

This study describes a group robot system “CHOBIE II”. The feature of the CHOBIE II is a function to form a reconfigurable structure. In the previous paper, we introduced a control method of the robots and realized transformation of the structure. In this paper, we focus on a motion planning method to obtain control algorithms. For this purpose, we introduce a numerical criterion for generating transformations. The criterion is expressed with matrix form of 32 parameters. This paper demonstrates the criteria generate various motions of the CHOBIE II, and proposes a new method to obtain the appropriate parameters for objective motions.
Optical Pumping of Helium in the<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi>S</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow><mml:mrow/><mml:mrow/><mml:mrow/><mml:mprescripts/><mml:mrow/><mml:mrow><mml:mn>3</mml:mn></mml:mrow><mml:mrow/><mml:mrow/></mml:mmultiscripts></mml:mrow></mml:math>Metastable State (1960)

The alignment of ${\mathrm{He}}^{4}$ atoms in the ($n=2$, metastable) $^{3}S_{1}$ state is described. Metastable atoms are produced by an rf discharge in a glass tube containing a few mm of pure helium, and the one micron pumping light ($2^{3}P\ensuremath{-}2^{3}S$) is provided by a helium lamp. A resonance signal is obtained from radio frequency disorientation by monitoring the transmitted pumping light. The double maximum line shape of this signal for strong rf magnetic fields is discussed. Included also is a discussion of the angular dependence of the signal when unpolarized light is used and an explanation of the inversion of the resonance signal for certain densities of the metastable helium atoms.The measured relaxation time of the oriented metastable atoms in the discharge is about 2.5\ifmmode\times\else\texttimes\fi{}${10}^{\ensuremath{-}4}$ second and the pumping time is about a millisecond. A method is proposed and initial measurements are given for the cross section for destruction of metastable helium atoms by collision with foreign gas atoms. The application of optical pumping in helium to the measurement of weak magnetic fields is also discussed.
Operational experiences of STATCOMs for wind parks (2009)

This paper points out the need for static synchronous compensators (STATCOMs) used in conjunction with wind parks. It describes the principles of operation of a medium voltage STATCOM and presents operational experiences based on installations in Great Britain and in Canada. Furthermore, value adding additional functions of a STATCOM are named.
Hierarchical Graph Attention Network for Visual Relationship Detection (2020)

Visual Relationship Detection (VRD) aims to describe the relationship between two objects by providing a structural triplet shown as <;subject-predicate-object>. Existing graph-based methods mainly represent the relationships by an object-level graph, which ignores to model the triplet-level dependencies. In this work, a Hierarchical Graph Attention Network (HGAT) is proposed to capture the dependencies on both object-level and triplet-level. Object-level graph aims to capture the interactions between objects, while the triplet-level graph models the dependencies among relation triplets. In addition, prior knowledge and attention mechanism are introduced to fix the redundant or missing edges on graphs that are constructed according to spatial correlation. With these approaches, nodes are allowed to attend over their spatial and semantic neighborhoods' features based on the visual or semantic feature correlation. Experimental results on the well-known VG and VRD datasets demonstrate that our model significantly outperforms the state-of-the-art methods.
A Vehicle Dispatch System Model Based on Weather and Road Condition (2009)

In the logistics industry, managing goods and dispatching vehicles property have been realized very important fields. We think safety of the transportation has been neglected, especially weather factor and road factor. Considering this problem, in this paper we presented a system prototype which can gather weather and road condition and use these information to help dispatch vehicles to improve safety of transportation. This prototype also can receive message from vehicle terminals and analyze discrepancies between actual data and planned data, furthermore, it can be used to revise the planned data.
Cancer vaccines: the challenge of developing an ideal tumor killing system (2005)

Despite the evidence that the immune system plays a significant role in controlling tumor growth in natural conditions and in response to therapeutic vaccination, cancer cells can survive their attack as the disease progresses and no vaccination regimen should be currently proposed to patients outside experimental clinical trials. Clinical results show that the immune system can be actively polarized against malignant cells by means of a variety of vaccination strategies, and that in some cases this is associated with tumor regression. This implies that under some unique circumstances, the naturally "dormant" immune effectors can actually be put at work and used as endogenous weapons against malignant cells. Consequently, the main challenge of tumor immunologists appears to lie on the ability of reproducing those conditions in a larger set of patients. The complexity of the immune network and the still enigmatic host-tumor interactions make these tasks at the same time challenging and fascinating. Recent tumor immunology findings are giving new impetus to the development of more effective vaccination strategies and might revolutionize the way of designing the next generation of cancer vaccines. In the near future, the implementation of these insights in the clinical setting and the completion/conduction of comparative randomized phase III trials will allow oncologists to define the actual role of cancer vaccines in the fight against malignancy.
Comparison of antibody avidity and titre elicited by peptide as a protein conjugate or as expressed in vaccinia. (1988)

The immunogenicity of a malaria peptide presented in various forms was tested in terms of the quality and quantity of the antibody response in rabbits. Peptide conjugated to a protein carrier, diphtheria toxoid (DT), required strong adjuvants (e.g. muramyl dipeptide, MDP and Freund's adjuvant, FCA) to elicit high levels of antibody with high avidity. Alum was a poor adjuvant, producing the lowest titre and avidity of antibody compared with all the other groups. Peptide expressed in vaccinia (and without carrier) produced intermediate levels of antibody but the avidity of the antibodies produced were comparable to that produced by peptide conjugates given with muramyl dipeptide.
Road infrastructure and economic development : some diagnostic indicators (1992)

The authors investigate the association between per capita income and the magnitude and quality of road infrastructure. They adopt an empirical approach, directly comparing or correlating a countries income with selected variables associated with existing road networks. Cross-section analysis of data from 98 countries, and time series analysis of U.S. data since 1950, show consistent and significant associations between economic development (per capita GNP) and road infrastructure (per capita length of paved network). The data shows that the per capita stock of road infrastructure in high income economies is dramatically greater than in middle- and low-income economies. For instance, the average density of paved roads (km/million inhabitants) varies from 170 in low-income economies to 1, 660 in middle-income and 10, 110 in high-income economies. That is, the average density of paved roads in high-income economies is 59 times that in the low-income group. Road conditions also seem to be associated with economic development: the density of paved roads in good condition varies from 40 km/million inhabitants in low-income economies to 470 middle-income and 8, 550 in high-income economies. The empirical information presented can be used as indicators of areas of weakness or strength in a country's stock of road infrastructure.
P‐6: Development of the RGBW TFT‐LCD with Data Rendering Innovation Matrix (DRIM) (2005)

Abstract To realize a bright TFT‐LCD for the mobile phone, we propose the QVGA RGBW TFT‐LCD with Data Rendering Innovation Matrix (DRIM) technology and a commercial one‐chip driver IC. A more efficient design with eight sub‐pixels makes high brightness and high contrast ratio possible with only 150 mW, low power consumption.
New generation of high-performance engines for space propulsion (1994)

Experimental data validating advanced engine designs at three thrust levels (5, 15, and 100 lbF) is presented. All of the three engine designs considered employ a Moog bipropellant torque motor valve, platelet injector design, and iridium-lined rhenium combustion chamber. Attention is focused on the performance, robustness, duration, and flexibility characteristics of the engines. It is noted that the 5- and 15-lbF thrust engines can deliver a steady state specific impulse in excess of 310 lbF-sec/lbm at an area ratio of 150:1, while the 150-lbF thrust engines deliver a steady state specific impulse of 320 lbF-sec/lbm at an area ratio of 250:1. The hot-fire test results reveal specific impulse improvements of 15 to 25 sec over conventional fuel film cooled columbium chamber designs while operating at maximum chamber temperatures.
Efficient gamut clipping for color image processing using LHS and YIQ (2003)

Out-of-gamut problems exist in color image processing and color reproduction in different devices. Extensive research has been done on transforming out-of-gamut colors to the inside of the output device's color gamut for color reproduction. We focus on the out-of-gamut problem in color image processing. Luminance, hue, and saturation (LHS) and YIQ color coordinate systems are investigated. Efficient techniques for luminance and saturation processing and gamut clippings are presented. The efficient technique of luminance clipping for LHS is developed based on scaling, and the efficient technique of luminance clipping for YIQ is developed based on shifting. However, the efficient technique of saturation clipping for both LHS and YIQ is a combination of scaling and shifting. Such efficient techniques reduce the complexity of forward and backward transformations between the color representing the color coordinate system (RGB) and the processing color coordinate system (LHS or YIQ) significantly. Illustrations show the result of RGB, luminance, and saturation clippings. Saturation clipping is the best in terms of maintaining the hue and contrast of the original image. Experiments are also conducted to measure the efficiency of the proposed efficient techniques. It shows that the processing time is reduced by 27% comparing with the conventional technique using forward and backward Color transformations.
SIMULATION TOOLS FOR DIGITAL LSI DESIGN (1983)

This thesis proposes a timing simulator (RSIM) based on a uniquely simple transistor model. RSIM allows a designer to determine both the functional and approximate timing characteristics of a MOS network with more accuracy than gate-level simulation, and using larger circuits than are accommodated by circuit analysis programs. In RSIM, transistors are modeled as resistors; the logic states of a transistor's terminal nodes determine its effective resistance.
Optically pumped GaInN/GaN multiple quantum wells for the realization of efficient green light-emitting devices (2013)

We report on a green light-emitting device, in which the light of an efficient blue 1 mm2 GaInN/GaN light-emitting diode (LED) is converted into green light by an optically pumped GaInN/GaN multiple quantum well structure. This solution reached an efficacy of 127 lm/W, i.e., higher than that of state-of-the-art 1 mm2 GaInN/GaN LEDs emitting directly at the target wavelength, at 350 mA current and 535 nm peak wavelength. Optically pumped converters overcome the design limitations of typical multiple quantum well LEDs, where carrier transport issues limit the maximum number of functioning wells and might help to solve the problem of the green gap.
Baseline frequency of brain metastases and outcomes with multikinase inhibitor therapy in patients with <i>RET</i>-rearranged lung cancers. (2017)

9069 Background: In phase 2 trials, multikinase inhibitors with activity against RET are active in a subset of patients (pts) with RET-rearranged lung cancers (response rate of 28%, phase 2 study of cabozantinib; Drilon et al Lancet Oncol 2016). Data on the incidence of brain metastases and outcomes with multikinase inhibitor therapy in pts with intracranial disease have not previously been reported. Methods: The frequency of brain metastases at diagnosis of metastatic disease was evaluated in pts accrued to a global registry of RET-rearranged lung cancer pts identified by a multicenter network of thoracic oncologists (Gautschi et al JCO 2017). A proportion of pts were treated with 9 multikinase inhibitors including cabozantinib, vandetanib, lenvatinib, alectinib, and ponatinib. On a prospective phase 2 trial (NCT01639508), patients with asymptomatic brain metastases were eligible. Intracranial response to cabozantinib (RECIST v1.1) was evaluated in an exploratory fashion. Results: 114 registry pts with RET-rearranged lung cancers had metastatic disease at diagnosis. Baseline brain metastases were identified in 27% (95%CI 18-34%, n = 20/75) of pts with available information. No differences (p > 0.05) in age, smoking history, or upstream fusion partner ( KIF5B100% vs 84%, with and without brain metastases, p = 0.53) were noted. In 37 pts treated with multikinase inhibitors with activity against RET, there were no significant differences in median PFS (2.1 vs 2.1 months, p = 0.41) or median OS (3.9 vs 7.0 months, p = 0.10) in pts with (n = 10) and without (n = 27) brain metastases. On a phase 2 trial of cabozantinib, baseline untreated brain metastases were present in 5 pts. Intracranial disease control (stable disease; -34% and -1% in 2 pts with measurable disease) was achieved in 4 of 4 pts with measurable or evaluable intracranial disease with time to treatment discontinuation ranging from 2.4 months to 2.9 years. Conclusions: Brain metastases are present in a substantial proportion of RET-rearranged lung cancer pts. Intracranial disease control can be achieved in select pts by a multikinase inhibitor. Novel RET-directed targeted therapy strategies should address intracranial disease. Clinical trial information: NCT01639508.
Protocol for PTEN Expression by Immunohistochemistry in Formalin-fixed Paraffin-embedded Human Breast Carcinoma (2010)

The PI3K/PTEN pathway plays a major role in carcinogenesis. Dysregulation of this pathway occurs frequently in breast cancer, and loss of PTEN expression is emerging as a potentially important mechanism of resistance to the widely used anti-HER2 therapy, trastuzumab. However, assays for loss of PTEN expression have suffered from lack of consistency. Here, we describe an automated and reliable protocol for PTEN protein expression by immunohistochemistry in formalin-fixed paraffin-embedded tissue that can be easily incorporated into clinical trials.
Enantiomeric separation by HPLC of 1,4‐dihydropyridines with vancomycin as chiral selector (2003)

The macrocyclic antibiotics represent a relatively new class of chiral selectors in CE, HPLC, and TLC. We have examined the use of the macrocyclic antibiotic vancomycin as a chiral selector in HPLC for the separation of 1,4-dihydropyridines (DHPs) calcium antagonists (CAs). Chromatographic data of six 1,4-dihydropyridine calcium channel blockers obtained on the vancomycin chiral stationary phase (Chirobiotic V) were compared with those obtained on an alpha(1)-acid glycoprotein (AGP) HPLC stationary phase. Optimization of pH and organic modifier was carried out in order to modulate the retention properties of each system. All chiral neutral DHPs were resolved on the AGP column, whereas on Chirobiotic V only basic DHPs showed a split peak. The analytical chromatographic procedure on Chirobiotic V proved suitable for semipreparative separation, since the separation factor on the analytical column was high enough to obtain pure enantiomers with high yields.
Sound and vibration of railroad wheel (2002)

Vibrations generated at the contact surfaces between rails and wheels have been considered to be the main cause of noise from railroad vehicles. These noises are classified into three types: rolling, impact, and screech noise. The generation mechanism of each noise has not yet been clarified. This study includes the calculation of natural frequencies of wheels based on elasticity theory, the laboratory test to measure the natural frequencies, the field test to measure the sound and vibration of a railroad wheel, and the analysis on the correlation between sound and vibration. Previous studies have not shown an explicit relationship between sound and vibration of a railroad wheel. The goal of this research is to explain noise from wheels by analyzing such a direct correlation. The result of this study designates that the origin of screech noise on a curved track comes from the lateral vibration of the wheel, and suggests that the vibration of the wheel has little direct contribution to rolling noise on a straight track.
<title>Fabrication of dielectric-coated silver hollow glass waveguides for the infrared by liquid-flow coating method</title> (1996)

Polyimide-coated silver hollow glass waveguides with small losses have been fabricated for transmission of Er:YAG laser light. The total loss is around 0.7 dB for the straight waveguide with an inner diameter of 700 micrometers and the length of 2.3 m including a coupling loss from a laser. Even when the waveguide is bent to 180 degrees with a bending radius of 18 cm, the total loss is around 1 dB for the input energy of 500 mJ.
Measurement of Non-Crystalline Calcium Phosphate in Bone Mineral. (1966)

SummaryIt was demonstrated by X-ray diffraction that bone mineral from mature cows, humans and Wistar rats, contained a non-crystalline calcium phosphate in addition to the well-known apatite phase. X-ray diffraction technique was described for determination of the percent of this amorphous (non-crystalline) material present in bone mineral, or synthetic mixtures.
Graphical simulation of the motion of articulated bodies such as humans and robots, with particular emphasis on the use of dynamic analysis (computer graphics, biomechanics) (1985)

Animation of articulated (jointed) bodies is of interest for several reasons. Inclusion of animal life in computer graphics images will increase their realism and interest. Computer graphical representations of the motion of humans and animals are useful tools in biology, biomechanics, medicine, and sports. Simulation of the motion of robots and other articulated machines using computer graphics can be useful for design and testing in CAD/CAM. Animation of articulated bodies presents a number of difficulties due to the complexity of possible motion. The usual method of specifying such motion is kinematics, which describes motion in terms of positions taken over time without consideration of the forces and torques causing the motion. An alternative means presented here is dynamics, where motion is described in terms of the influence of forces and torques on mass to cause acceleration. Although more complex and computationally expensive, dynamic analysis does predict motion that is realistic for the conditions specified. Advantages and disadvantages of the two methods are discussed. For ease of use, both methods would require high-level control routines so that the user could describe the motion in general terms (what to do), rather than the details of local joint behavior (how to do it). A system, Deva, is described which combines the facility for both kinematic and dynamic animation of articulated bodies.
N-bridged heterocycles. Preparation and properties of 1,3-polymethylene-benzimidazolium salts and related systems (1973)

A series of benzimidazolium chlorides, and benzimidazole-ones and -thiones with polymethylene chains of between 5 and 12 members linking the 1- and 3-positions have been made and their chemical and spectroscopic properties examined.
Phosphorylation by DNA-Dependent Protein Kinase Is Critical for Apoptosis Induction by Insulin-Like Growth Factor Binding Protein-3 (2006)

Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) promotes apoptosis of cancer cells by both IGF-dependent and IGF-independent mechanisms. In vitro phosphorylation of IGFBP-3 by DNA-dependent protein kinase (DNA-PK) has been reported but with unknown functional relevance. Using a chemical inhibitor for DNA-PK in prostate cancer cells and a paired system of glioblastoma cell lines that either lack or express DNA-PK, we show that the apoptosis-promoting and growth-inhibitory actions of IGFBP-3 are completely abrogated in the absence of catalytically active DNA-PK. In the absence of DNA-PK activity, IGFBP-3 has reduced nuclear accumulation and is unable to bind its nuclear binding partner retinoid X receptor (RXR) alpha. We assessed the importance of the three potential DNA-PK phosphorylation sites in IGFBP-3 using PCR-based site-directed mutagenesis. When transfected into 22RV1 cells, IGFBP-3-S165A and IGFBP-3-T170A functioned in an identical manner to wild-type IGFBP-3 to induce apoptosis. In contrast, IGFBP-3-S156A was unable to promote apoptosis and exhibited reduced nuclear accumulation, suggesting a key role for DNA-PK-dependent phosphorylation in the regulation of IGFBP-3 action. These studies reveal a novel regulatory mechanism for the actions of IGFBP-3 in prostate cancer and show phosphorylation of Ser(156) to be functionally critical in its apoptosis-inducing actions.
An adaptive virtual simulation and real-time emergency response system (2009)

Virtual simulation has been playing an important role in many areas including gaming, training, e-learning, and etc. At the mean time, real-time emergency response system is attracting more and more attention due to its significance to reduce the casualties and properties lost when disasters come. Indeed, a highly responsive and effective real-time response system depends on a well designed architecture, in particular, a distributed virtual simulation environment which not only can train the emergency response personnel, but also can be used as a core real-time strategy and response system. In this paper, we propose an integrative and adaptive distributed real-time simulation environment which aims at providing a more efficient and flexible virtual environment to meet the requirement of today's high-end emergency response class of applications. Our proposed system is based in service oriented design and most advanced P2P network technique. The goal of our system is to build a robust software framework to make the real-time emergency response system more flexible and more scalable.
MORE ABOUT THE ALDINE PLINY OF 1508 (1935)

MORE ABOUT THE ALDINE PLINY OF 1508 ARTHUR E. CASE ARTHUR E. CASE Search for other works by this author on: Oxford Academic Google Scholar The Library, Volume s4-XVI, Issue 2, September 1935, Pages 173–187, https://doi.org/10.1093/library/s4-XVI.2.173 Published: 01 September 1935