gebhart/patrepeval huggingface dataset:
Regulation of AmtR‐controlled gene expression in <i>Corynebacterium glutamicum</i>: mechanism and characterization of the AmtR regulon (2005)

AmtR, the master regulator of nitrogen control in Corynebacterium glutamicum, represses transcription of a number of genes during nitrogen surplus. Repression is released by an interaction of AmtR with signal transduction protein GlnK. As shown by pull-down assays and gel retardation experiments, only adenylylated GlnK, which is present in the cells during nitrogen limitation, is able to bind to AmtR. The AmtR regulon was characterized in this study by a combination of bioinformatics, transcriptome and proteome analyses. At least 33 genes are directly controlled by the repressor protein including those encoding transporters and enzymes for ammonium assimilation (amtA, amtB, glnA, gltBD), urea and creatinine metabolism (urtABCDE, ureABCEFGD, crnT, codA), a number of biochemically uncharacterized enzymes and transport systems (NCgl1099, NCgl1100, NCgl 1915-1918) as well as signal transduction proteins (glnD, glnK). For the AmtR regulon, an AmtR box has been defined which comprises the sequence tttCTATN6AtAGat/aA. Furthermore, the transcriptional organization of AmtR-regulated genes and operons was characterized.
Role of Xanthine Oxidase and Its Inhibitor in Hypoxia: Reoxygenation Injury (1996)

XDH and XO are released from the liver during hypoxic conditions, for instance, and consequently, they may reach a number of organs via the circulation.
Stabilized Polymers with Novel Indenoindene Backbone against Photodegradation for LEDs and Solar Cells (2008)

PPV derivatives, polymers with vinylene units, have their tendency to exhibit degradation, after irradiation with white light or operation of the device, resulting in the appearance of a shifted absorption and emission band in the short wavelength regions of the spectra. In this paper, we report the synthesis and properties of new polymers utilizing new backbone, poly(5,5,10,10-tetrakis(2-ethylhexyl)-5,10-dihydroindeno[2,1-a]indene-2,7-diyl) (PININE). In order to reduce oxidation of the vinylene group, the vinylene group was cyclized using two 5-membered rings. While poly(p-phenylenevinylene) derivatives show significantly blue-shifted and decreased peaks of UV−vis, blue-shifted maximum peaks of photoluminescence (PL) after irradiation with white light in air, and blue-shifted maximum peaks of electroluminescence (EL) after operation of the device, PININE shows stable spectra of UV−vis, and PL, and EL under the same conditions. PININE copolymers with benzothiadiazole and thiophene units exhibit high power conversion efficiency (PCE) for polymer solar cells. Under white light illumination (AM 1.5 G, 100 mW/cm2), the cell based on PININEDTBT/PCBM as the active layer has a short circuit current density (Isc) of 5.93 mA/cm2, a fill factor (FF) of 43%, and PCE of 1.88%. These copolymers have not only good processability due to the indenoindene unit, in which four alkyl groups can be incorporated, but also strong and uniform absorbance in the whole visible region.
General approach to block-matching motion estimation (1993)

A general approach to block-matching motion estimation is introduced. It very well handles the complex motion found in broadcasting television signals by comparing each block of the current frame with a deformed quadrilateral of the previous one. Calculation of the extra motion information requires additional operations that increase the computational load but the improved prediction reduces the bit rate. It is shown that the proposed method outperforms the conventional full search method by improving the overall SNR of the prediction error by at least 1 dB and reducing the bit rate by 10%.
Characterization of a macrophage-derived plasminogen-activator inhibitor. Similarities with placental urokinase inhibitor (1985)

Human and mouse macrophages release a fibrinolytic inhibitor after stimulation by endotoxin in vitro. The released mouse inhibitor was indistinguishable in size by molecular-sieve chromatography from an intracellular form (approx. 50 kDa), and both inhibitors blocked urokinase directly as judged by a 125I-plasminogen conversion assay. The intracellular inhibitor was found mostly to dissociate from 125I-urokinase during sodium dodecyl sulphate/polyacrylamide-gel electrophoresis under reduced conditions, but a dodecyl sulphate-stable complex at 65-67 kDa was observed. Because of similarities in the reported size, stability and urokinase-binding properties of a placental urokinase inhibitor, the kinetic properties of the two inhibitors were compared. Under the reaction conditions employed (37 degrees C at pH7.4 in the presence of 0.2% Triton X-100), the association rate constants and equilibrium dissociation constants of the two inhibitors were indistinguishable, 3 X 10(5) M-1 X s-1 and 4 X 10(-10) M respectively. These data show that peritoneal macrophages contain a plasminogen-activator very similar to a previously recognized placental inhibitor. Although the inhibitor appears to be a trace protein in macrophages, placental macrophages may account for the accumulation of the inhibitor in placental tissue.
STUDIES ON CELLULOSE CHEMISTRY. III. PARABROMO-ACETALDEHYDE AND MONOBROMO-ACETALDEHYDE. THEIR PREPARATION, PROPERTIES AND UTILIZATION FOR THE SYNTHESIS OF BROMO- AND HYDROXY-CYCLIC ACETALS RELATED TO POLYSACCHARIDES (1923)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSTUDIES ON CELLULOSE CHEMISTRY. III. PARABROMO-ACETALDEHYDE AND MONOBROMO-ACETALDEHYDE. THEIR PREPARATION, PROPERTIES AND UTILIZATION FOR THE SYNTHESIS OF BROMO- AND HYDROXY-CYCLIC ACETALS RELATED TO POLYSACCHARIDESHarold Hibbert and Harold S. HillCite this: J. Am. Chem. Soc. 1923, 45, 3, 734–751Publication Date (Print):March 1, 1923Publication History Published online1 May 2002Published inissue 1 March 1923https://pubs.acs.org/doi/10.1021/ja01656a027https://doi.org/10.1021/ja01656a027research-articleACS PublicationsRequest reuse permissionsArticle Views195Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Adsorbate Transport on Graphene by Electromigration (2012)

Chemical functionalization of graphene holds promise for various applications ranging from nanoelectronics to catalysis, drug delivery, and nanoassembly. In many applications it is important to be able to transport adsorbates on graphene in real time. We propose to use electromigration to drive the adsorbate transport across the graphene sheet. To assess the efficiency of electromigration, we develop a tight-binding model of electromigration of an adsorbate on graphene and obtain simple analytical expressions for different contributions to the electromigration force. Using experimentally accessible parameters of realistic graphene-based devices as well as electronic structure theory calculations to parametrize the developed model, we argue that electromigration on graphene can be efficient. As an example, we show that the drift velocity of atomic oxygen covalently bound to graphene can reach ~1 cm/s.
Recommendation Systems for Software Engineering (2009)

Software development can be challenging because of the large information spaces that developers must navigate. Without assistance, developers can become bogged down and spend a disproportionate amount of their time seeking information at the expense of other value-producing tasks. Recommendation systems for software engineering (RSSEs) are software tools that can assist developers with a wide range of activities, from reusing code to writing effective bug reports. The authors provide an overview of recommendation systems for software engineering: what they are, what they can do for developers, and what they might do in the future.
Development of control application using power line communication (2014)

Power line communication (PLC) based simple control application developed using LonWorks network technology is addressed in this paper. PLC enables sharing of data among intelligent devices at hundreds of Mbps (Mega bits per second). Test result of this application at shorter and longer distances and also the communication error that occurred during transmission of data is discussed.
In Vivo Retinal Tolerance of Various Heavy Silicone Oils (2007)

Biocompatibility of the new HSOs is dependent on the lipophilic behavior (R(F)/R(H) ratio) and furthermore on the molecular dimension of the used semifluorinated alkanes (SFAs). HSOs on the basis of F4H5 may have advantages over silicone oils, on the basis of F6H8, for use as a tamponade agent for the inferior retina in difficult retinal situations.
A new gate circuit performing fault protections of IGBTs during short circuit transients (2003)

Short circuit faults of IGBTs determine overcurrent through the devices subsequently to a turn-on switching or during the on-state condition, leading respectively to hard switching fault (HSF) or fault under load (FUL). Firstly, the state of the art as appearing in literature is recalled and discussed. A new short-circuit protection scheme, which allows protection of IGBT devices against fault under load and hard switching fault transients, is presented. It performs the fault current limiting action within the short circuit time, and subsequently forces the device to gate on again in a tentative turn-on. Moreover, the proposed circuitry allows strong bounding of the peak of the current in FUL transients. The validity and correctness of the proposed approach has been extensively validated by experimental tests.
Chemical vapor deposition of ultrathin Ta2O5 films using Ta[N(CH3)2]5 (1998)

Tantalum oxide films were deposited on Si substrates by chemical vapor deposition using the precursor Ta[N(CH3)2]5, and an oxidizing agent—O2, H2O, or NO. Temperatures ranged between 400 and 500 °C and total pressures between 10−3 and 9 Torr. NO did not lead to satisfactory film growth rates. Insignificant (&lt;1 at. %) N and up to a few percent C are incorporated when O2 is the oxidant and the total pressure is in the Torr regime. In the milliTorr regime, the Ta2O5 films, grown using either O2 or H2O, contain readily detectable amounts of C and N. For the films grown with O2 in the Torr regime, leakage currents were significantly lowered when the flow rate of O2 increased from 100 to 900 sccm.
Dopants for organic light-emitting devices (2015)

Organic light-emitting devices (OLEDs) with two-component layers consisting of a guest material (dopant) dispersed in a matrix (host) are examined in this work. Both emissive organic materials as dopants and non-emissive conductivity dopants are discussed. For the conductivity doping, lithium-coordinating agents including cryptands and crown ether derivatives have been used as dopants for electron-transport layers to improve the device operating voltages and luminance. Devices with oxidatively doped hole-transport layers consisting of novel hole-transporting ferrocene derivatives are also described. For the emissive doping, the spectral line shape dependence on the varied host materials for the emission of phosphorescent iridium complexes is examined. It has been shown that the value of Huang-Rhys parameters for the phosphorescence spectra decreases several times when non-polar ultra-high-band-gap hosts (UGHs) are used, compared to conventional carbazole-based host materials. Finally, a new class of efficient blue fluorescent dopants specifically designed as blue components for the white OLEDs with separate channels of harvesting blue singlet and red and green triplet excitons has been characterized.
Similarities between a predicted secondary structure for the M1 RNA ribozyme and the tRNA binding center of 16 S rRNA from <i>E. coli</i> (1987)

We propose a new model for the secondary structure of the M1 RNA component of E. coli RNase P which is based on significant sequence homologies with parts of the E. coli 16 S rRNA. A large domain of the new model resembles closely the secondary structure of the tRNA binding center of 16 S rRNA. We suggest that this domain of M1 RNA when functioning as a ribozyme binds the mature part of the precursor tRNA.
A slotted ALOHA packet radio system with multiple antennas and receivers (1990)

The problem of data transmission in a mobile packet radio system with one central base station and a number of mobile terminals is addressed. A method using multiple directional antennas and receivers at the base station to improve the efficiency of transmission on the inbound channel (from the terminals to the base station) is proposed. A number of channel models are considered, including flat terrestrial propagation loss, Rayleigh fading, and noise. A finite population Markov model is used to obtain the throughput of a multiantenna and multireceiver slotted ALOHA system. Numerical results indicate that substantial gains are possible with the use of several antennas and receivers. The dynamic behavior of the system is also improved.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Multiple Translational Isoforms Give Functional Specificity to Serum- and Glucocorticoid-induced Kinase 1 (2007)

Serum- and glucocorticoid-induced kinase 1 is a ubiquitous kinase that regulates diverse processes such as ion transport and cell survival. We report that a single SGK1 mRNA produces isoforms with different N-termini owing to alternative translation initiation. The long isoforms, 49 and 47 kDa, are the most abundant, localize to the ER membrane, exhibit rapid turnover, their expression is decreased by ER stress, activate the epithelial sodium channel (ENaC) and translocate FoxO3a transcriptional factors from the nucleus to the cytoplasm. The short isoforms, 45 and 42 kDa, localize to the cytoplasm and nucleus, exhibit long half-life and phosphorylate glycogen synthase kinase-3beta. The data indicate that activation of Sgk1 in different cellular compartments is key to providing functional specificity to Sgk1 signaling pathways. We conclude that the distinct properties and functional specialization of Sgk1 given by the N-terminus confer versatility of function while maintaining the same core kinase domain.
Injection Molding of Microcomposites Based on Polypropylene and Thermotropic Liquid Crystalline Polymers (1996)

Abstract This work is concerned with the injection molding of pellets of polypropylene (PP) containing pregenerated microfibrils of thermotropic liquid crystal polymers (TLCPs), referred to as microcomposites. The TLCPs used are HX6000 and Vectra A950. The microcomposites are produced by drawing strands of PP and TLCPs generated by means of a novel mixing technique and pelletizing the strands. The work was undertaken in an effort to improve on the properties observed for in situ composites in which the TLCP fibrils are generated during mold filling. In situ composites usually exhibit highly anisotropic mechanical properties and the properties do not reflect the full reinforcing potential of the TLCP fibers. Factors considered include the effect of in situ composite strand properties on the properties of the injection molded composite, the melt temperature used in injection molding, TLCP concentration, and the melt temperature of the TLCP. It is found that when processed at appropriate temperatures, the TLCP microfibrils are maintained through injection molding, and the composites show a good balance between machine and transverse direction properties (with ratios of the machine and transverse direction moduli ranging from 1.1 toto 1.35). The use of HX6000 rather than Vectra A allows for higher processing temperatures to be used during injection molding. The moduli of the injection molded composites increase with both increasing TLCP composition and in situ composite strand moduli. At 10 wt.-% TLCP the moduli of the injection molded composites approach the predictions of composite theory while at 20 and 30 wt.-% TLCP negative deviations from the theoretical moduli are seen. This is believed to be the result of a loss of fiber aspect ratio from fiber breakage and agglomeration. It is believed that with future studies on the effect of shear and elongational stresses during processing on the aspect ratio of the fibers a means of overcoming this problem may be found. The modulus of a 20 wt.-% HX6000 composite is similar to that of a 20 wt.-% glass composite (3.21 GPa versus 3.66 GPa), but the tensile strength of the HX6000 composite is about 28 % lower than that of the glass composite. It is expected that as the modulus and strength of the reinforcing TLCP fibrils are improved the properties of the injection molded microcomposites should exceed those of glass reinforced composites.
477-P: The National Diabetes Prevention Program (National DPP): What the New Variables Are Telling Us about Outcomes (2021)

In 2018, the Centers for Disease Control and Prevention (CDC) began requiring organizations recognized through the National DPP Diabetes Prevention Recognition Program (DPRP) to collect new information from participants at the time of enrollment: referral source (ENROLL), payer source (PAYER), and highest level of completed education (EDU). Of the 354,616 participants who enrolled in, and had the opportunity to complete, the National DPP lifestyle change program as of October 2020, analyses were restricted to the 63,598 who enrolled from March 2018 through February 2019 to ensure that information was complete. With respect to referral source, participants who decided on their own to enroll (option of “self”), or who reported the option of “primary care provider/office or specialist”, attended the most sessions on average (17.6 and 17.5 sessions, respectively). The least number of sessions attended (mean of 13.7) was associated with those who reported the option of “employer or employer’s wellness program.” While most participants reported a PAYER option of “private insurer”, they attended a mean of 14.2 sessions. The mean number of sessions attended by those reporting a PAYER of “Medicare” was 19.2. College graduates reported attending the most sessions, on average, 15.1, yet 50% attended at least 12. Fifty percent of those with less than a high school education attended at least 15 sessions. With respect to mean weight loss % and referral source, the highest (5.6%) was achieved by those who chose the ENROLL option of “media.” Those who chose “employer or employer’s wellness program” lost the least, 3.7%. When stratified by PAYER, those who chose “Medicare” lost the most weight (6.9% on average). Level of education did not have much impact on mean weight loss with a range of 4% to 4.5% across the four options. The collection of this additional information provides important insights into who is currently meeting programmatic goals. Disclosure E. Ely: None. M. Bell: None.
A 0.0004% (−108dB) THD+N, 112dB-SNR, 3.15W fully differential Class-D audio amplifier with G<inf>m</inf> noise cancellation and negative output-common-mode injection techniques (2018)

Flicker (1/f) noise is a main design issue when realizing a low-noise and high-SNR audio amplifier. Utilizing large device sizes and chopper-stabilization techniques are commonly adopted approaches to mitigate 1/f noise. However, the choppers are seldom used in pulse-width-modulation (PWM) Class-D audio amplifiers (CDAs) because the conventional chopping method applied in the opamps along the signal path of CDAs inevitably results in extra aliasing and deteriorates the linearity. Therefore, a CDA with high SNR and low total harmonic distortions (THDs) has become a challenging design to ensure high-fidelity audio applications.
Mining Method Handle Graphs for Efficient Dynamic JVM Languages (2015)

The Java Virtual Machine (JVM) has been used as an execution platform by many dynamically-typed programming languages such as Ruby, Python, and Groovy. The main challenge to compile such dynamic JVM languages is choosing the most appropriate implementation of a method for various types of an object at runtime. To address this challenge, a new Java bytecode instruction, invokedynamic, has been introduced, allowing users to control the linkage between a call site and a method implementation. With this instruction, a method handle that refers to a method is linked to the call site and then potentially transforms the invocation to a real implementation. As a referenced method of a method handle might in turn refer to other method handles, multiple method handles constitute a Method Handle Graph (MHG).
Long-range spontaneous structural ordering in barium stannate thin films (2010)

We have studied spontaneous structural ordering in epitaxial barium stannate thin films, grown on SrTiO3(001) substrates by pulsed laser deposition. X-ray diffraction analysis revealed satellite reflections around the Bragg peaks, indicative of nanoscale periodic ordering in the out-of-plane direction. We find that mass transport strongly affects this spontaneous ordering, and that the thin film growth rate can be used to tune the periodicity of the superlattices, here between 4.3 and 57.7 nm.
Kinetic Effects on Self‐Assembly and Function of Protein–Polymer Bioconjugates in Thin Films Prepared by Flow Coating (2016)

The self-assembly of nanostructured globular protein arrays in thin films is demonstrated using protein-polymer block copolymers based on a model protein mCherry and the polymer poly(oligoethylene glycol acrylate) (POEGA). Conjugates are flow coated into thin films on a poly(ethylene oxide) grafted Si surface, forming self-assembled cylindrical nanostructures with POEGA domains selectively segregating to the air-film interface. Long-range order and preferential arrangement of parallel cylinders templated by selective surfaces are demonstrated by controlling relative humidity. Long-range order increases with coating speed when the film thicknesses are kept constant, due to reduced nucleation per unit area of drying film. Fluorescence emission spectra of mCherry in films prepared at <25% relative humidity shows a small shift suggesting that proteins are more perturbed at low humidity than high humidity or the solution state.