gebhart/patrepeval huggingface dataset:
Arsenic–π Interactions Stabilize a Self‐Assembled As<sub>2</sub>L<sub>3</sub> Supramolecular Complex (2004)

An As2L3 metallocryptand is the result of a new predictive design strategy for forming self-assembled supramolecular arsenic complexes. The assembly is remarkably stable to a variety of competing metal ions, harsh acid, and excess ligand. X-ray crystallographic studies and density functional calculations suggest that a strong arsenic–π interaction adds stability to the structure.
Stresses in Dual-Coated Optical Fibers (1988)

We examine several problems related to the mechanical behavior of dual-coated optical fibers: low temperature microbending, evaluation of spring constant due to coating layers, strength of the end portions of fibers clamped in termination fixtures, and prediction of stresses caused by the misalignment of the openings in the frame and the termination fixture. The developed formulas are simple, easy-to-use and clearly indicate the role of the major factors affecting the mechanical behavior of the fibers. The obtained results can be of help in physical design of dual-coated fibers and optical interconnections.
Formation of Bubbles by Electrochemical Processes in Glass (1966)

Bubble formation at both electrodes in the systems metal | glass | oxide, metal is investigated by short‐circuiting, or application of an electromotive force. The systems investigated included noble metals, soda‐lime‐silicate glass, and simple or complex oxides which operate as electronic or ionic conductors. Oxygen was considered as the main gaseous component produced by an electrochemical process. The analysis of the current‐potential curves defining the kinetics of the electrochemical processes on the surface of two electrodes, points to the possible existence and the importance of bubble formation when two electrodes are short‐circuited.
Implantation, interception and contraception* (1994)

The factors involved in post-fertilization events leading to implantation in mammals are discussed with special reference to potential forms of interception. The stages of embryonic growth until implantation are considered initially. The growth and differentiation of the uterine endometrium is then described, followed by the events occurring during the apposition and invasion of the implanting embryo. Several potential approaches to new forms of interception are considered, and the advantages and disadvantages of each of them are evaluated. Among them, new vaccines against the zona pellucida, inactivation of the secretions of the blastocyst, hatching, the activity of pinopodes, and the endometrial proteins produced in the secretory phase seem to offer various and varied targets. Some existing methods of fertility regulation may act by affecting these stages of development, e.g. RU486 may interfere with pinopod function. Various physiological and embryonic consequences of interfering with these stages of pregnancy are discussed.
Eye–hand strategies in copying complex lines (2008)

Eye movements and eye-hand interactions have been recorded for 10 beginner art students copying complex lines representing outlines of caricature heads seen in profile. Four copying conditions mimicking real-world drawing situations were tested: Direct copying where the original and copy were placed side by side, Direct Blind copying where the subject could not see the drawing hand and copy, Memory copying where the original was first memorized for drawing and subsequently hidden before drawing commenced, and Non-specific Memory copying where the original was encoded for facial recognition before being hidden and drawn from memory. We observed four very different eye-hand interaction strategies which provide evidence for the eye's dual role in the copying process: acquiring visual information in order to activate the visuomotor transformation and guiding the hand on the paper. The Direct copying strategies were best understood in terms of a Drawing Hypothesis stating that shape is the result of visuomotor mapping alone and, consequently, can be accurately drawn without vision of the drawing hand or paper. A double just-in-time mechanism is proposed whereby the eye refers alternatively to the original for shape and to the copy for spatial position just in time for the drawing action to proceed continuously.
Antihypertensive Agents. III.<sup>1</sup> 3-Hydroxy-3-phenylphthalimidines (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntihypertensive Agents. III.1 3-Hydroxy-3-phenylphthalimidinesJohn G. Topliss, Leroy M. Konzelman, Nathan Sperber, and Franklin E. RothCite this: J. Med. Chem. 1964, 7, 4, 453–456Publication Date (Print):July 1, 1964Publication History Published online1 May 2002Published inissue 1 July 1964https://doi.org/10.1021/jm00334a012RIGHTS & PERMISSIONSArticle Views242Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (423 KB) Get e-Alertsclose Get e-Alerts
Predictions of response to artificial selection from new mutations (1982)

SUMMARY The pattern of response expected from fixation of mutant genes for quantitative traits in finite populations is investigated for a range of distributions of mutant gene effects. The eventual rate depends on the total variance of mutant effects per generation, but the initial rate and the variance of response is higher if the distribution of mutant effects has a large standard deviation or is leptokurtic. The difference between initial and eventual rates of response is greater with large population sizes. For a range of assumptions, new mutants are unlikely to have much influence on response for 20 or so generations, but then may contribute substantially, such that no plateaux are obtained. However, information on the variance contributed by mutants is almost entirely on bristle number in Drosophila . It is argued that the role of new mutants should be considered in designing breeding programmes, in particular in utilizing large populations.
Chronic hepatitis C and superimposed nonalcoholic fatty liver disease (2001)

In patients with chronic hepatitis C, type 2 DM and superimposed steatohepatitis are independently associated with advanced fibrosis.
Synthesis of 2,3,5-trihydroxyphenylprop-1-ene and its 4-chloro-, 6-chloro-, and 4,6-dichloro- derivatives (1987)

The synthesis of (E)-2,3,5-trihydroxyphenylprop-1-ene (2) and its 4-chloro-(3), 6-chloro-(4), and 4,6-dichloro- derivatives (5) is described. The routes involve the key intermediates, methyl 2,3,5-tribenzyloxybenzoate (15) and methyl 2,3,5-tribenzyloxy-4-chlorobenzoate (41) which were prepared from vanillin and 3,5-dimethoxytoluene (33), respectively. The benzoates (15) and (41) were treated with the anion from ethylphosphonic bis(dimethylamide)(6) to give the corresponding β-oxophosphonamides (17) and (42). These were reduced with sodium borohydride to the β-hydroxyphosphonamides (19) and (29), respectively. The benzyl protecting groups were removed by hydrogenolysis and subsequent treatment with acid gave the required phenylpropenes (2) and (3). The 6-chloro derivatives (4) and (5) were prepared via chlorination of the β-acetoxyphosphonam ides (27) and (44), respectively.
Systematic reviews of the role of omega-3 fatty acids in the prevention and treatment of disease (2012)

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La restauration du patrimoine aux États-Unis : évaluation critique et orientations (2005)

L'objectif de cet article est, d'une part de dresser un bilan des résultats de la sauvegarde et de la restauration du patrimoine architectural urbain des États-Unis, et d'autre part de définir les divers concepts qui sont invoqués par les défenseurs du patrimoine.L'auteur constate d'abord, qu'à de rares exceptions, les paysages urbains des XVIIIe et XIXe siècles ont été détruits. L'une des principales causes de l'échec de la sauvegarde du patrimoine aux États-Unis est l'absence de conscience historique chez les Américains. L'histoire et les objets qui s'y rattachent sont considérés comme une marchandise.Mais il existe cependant un certain attachement romantique pour le passé qui s'exprime, souvent maladroitement, faute de pouvoir s'appuyer sur des concepts de restaurationbien définis. L'auteur analyse ensuite les divers concepts utilisés par les défenseurs des paysages historiques :— la « mémoire culturelle », qui invoque la fidélité au passé ;— la « patine du temps » qui est l'expression d'une perception esthétique et sensuelle des vieux objets ;— la « proxémie », qui est en relation avec la notion de voisinage et la qualité de l'environnement social ;— la « diversification de l'environnement », telle qu'elle existait autrefois, est un paliatif à la motonomie de l'architecture moderne ;— la valeur économique est un concept qui vise à appliquer les analyses coûts-bénéfices aux opérations de restauration. Le cas de la sauvegarde du Vieux-Carré, à la Nouvelle-Orléans, est ensuite présentécomme une réussite sur le plan architectural, mais un succès discutable sur leplan social, puisque la population pauvre, des noirs en majorité, a été chassée du quartier par les loyers trop élevés. En conclusion l'auteur insiste sur ia nécessité de bien définir les principes directeurs dans toute opération de restauration du patrimoine.
Structure of Antioxidative Compounds in Ginger (1994)

Fourteen gingerol related compounds and seven diarylheptanoids were isolated from ginger rhizomes. Their structures were elucidated on the basis of chemical and spectroscopic evidence. Most of the isolated compounds exhibited stronger antioxidative effect than α-tocopherol. The antioxidant activity depended upon substituents on the side chain and benzene ring, and the length of side chain.
Comparison of enzymatic reactivity of corn stover solids prepared by dilute acid, AFEX™, and ionic liquid pretreatments (2014)

Initial hydrolysis yields were highest for substrates with greater lignin removal, a greater degree of change in cellulose crystallinity, and high enzyme accessibility. Final glucose yields could not be clearly related to concentrations of xylooligomers released from xylan during hydrolysis. Overall, none of these factors could completely account for differences in enzymatic digestion performance of solids produced by AFEX, DA, and IL pretreatments.
Tristan de Luna, Conquistador of the Old South: A Study of Spanish Imperial Strategy (1936)

Journal Article Tristán de Luna, Conquistador of the Old South: A Study of Spanish Imperial Strategy. By Herbert Ingrain Priestley. (Glendale, California: The Arthur H. Clark Company, 1936. vi+215 pp. $5.00.) Get access Lawrence F. Hill Lawrence F. Hill Ohio State University Search for other works by this author on: Oxford Academic Google Scholar Journal of American History, Volume 23, Issue 2, September 1936, Page 252, https://doi.org/10.2307/1893274 Published: 01 September 1936
Diet-induced adipocyte number increase in adult rats: a new model of obesity. (1978)

Adult rats of various strains became obese when they were fed a highly palatable diet for several months. Analysis of their adipose tissue morphology revealed increases in both adipocyte size and number in most depots. Reintroduction of an ordinary chow diet to such animals precipitated a period of weight loss during which only mean adipocyte size returned to normal. Adipocyte number remained at the elevated level achieved during the period of weight gain. Thus, transient dietary obesity in rats results in a persistent obesity of a purely hyperplastic, nonhypertrophic form. Furthermore, the persistence of the cell number increase suggests that it is the result of proliferation or differentiation rather than of only an increase in the lipid content of a pool of very small and normally undetected adipocytes. An analysis of adipose tissue morphology changes during the course of diet-induced weight gain suggests that the achievement of some specific mean adipocyte size triggers the events that culminate in adipocyte number increase. What mechanisms may link adipocyte size to the formation of new adipocytes remains unknown.
PROBABILISTIC ESTIMATION OF EXTREME CLIMATOLOGICAL PARAMETERS OVER ZIM -BABWE. (1984)

Keywords PROBABILITY, ESTIMATING, PARAMETERS, CLIMATOLOGY, DATA, CLIMATE, STATISTICS, ANALYSIS, WIND, EXTRAPOLATION, CALCULATIONS, MODELS, PREDICTION, DATABASES, METHODS, SENSITIVITY, DESIGN, SPEED, MEAN, STRUCTURES, WEATHER, PLOTTING ZIMBABWE, AFRICA... Show All
Recycling Technique in Preparative Liquid Chromatography (1981)

Abstract A theoretical and practical study of recycling technique is developped for preparative liquid chromatography. The optimal cycle number, nopt, is determined for the separation of two solutes in such a way that the resolution between the second peak of cycle (n-1) and the first one of cycle n is equal to the resolution between the peaks of cycle n. A simple relationship is propounded to determine nopt which only depends on retention volumes and external volume, but it does not depend on band spreading. With this recycling technique it is shown that the maximum injection volume under optimal recycling conditions is greater than nopt times the maximum injection volume for one cycle. So the use of recycling can be opportune and beneficial to increase the throughput in preparative liquid chromatography.
Comparison of the sensitivity to rotation of pilots and nonpilots. (1972)

Thirty-six airline pilots and 56 nonpilots were tested to determine their sensitivity to rotation. A staircase procedure was used to determine oculogyral illusion and perception of rotation thresholds, in a precision rotation device. The results indicated that (1) there were no significant differences between the two groups for either threshold measure, (2) the thresholds for the oculogyral illusion were significantly lower than the perception of rotation thresholds for both groups, and (3) changes in threshold as a function of age were minimal for 91 of the men. The validity and results of the tests are discussed with regard to the pilot's use of motion information in control tasks for aircraft and simulators.
A unique and precarious office- The office of Governor-General (2002)

Extract: The Governor-General of Australia occupies a unique position in our constitutional system. The appointee is personally selected by the Prime Minister, and formally appointed by the Queen under s 2 of the Constitution. In the same way, the occupant of the office is removed from office by the Queen on the instructions of the Prime Minister. No grounds nor process are prescribed for removal. The unprecedented calls for the resignation of the current Governor-General, Dr Hollingworth, the former Anglican Archbishop of Brisbane, highlight this gap in our constitutional arrangements.
Quantifying the Independence of Human Finger Movements: Comparisons of Digits, Hands, and Movement Frequencies (2000)

To determine whether other digits move when normal humans attempt to move just one digit, we asked 10 right-handed subjects to move one finger at a time while we recorded the motion of all five digits simultaneously with both a video motion analysis system and an instrumented glove. We quantified the independence of the digits to compare (1) the different digits, (2) the right versus the left hand, and (3) movements at a self-paced frequency versus externally paced movements at 3 Hz. We also quantified the degree to which motion occurred at the proximal, middle, or distal joint of each digit. Even when asked to move just one finger, normal human subjects produced motion in other digits. Movements of the thumb, index finger, and little finger typically were more highly individuated than were movements of the middle or ring fingers. Fingers of the dominant hand were not more independent than were those of the nondominant hand. Self-paced movements made at approximately 2 Hz were more highly individuated than were externally paced movements at 3 Hz. Angular motion tended to be greatest at the middle joint of each digit, with increased angular motion at the proximal and distal joints during 3 Hz movements. Simultaneous motion of noninstructed digits may result in part from passive mechanical connections between the digits, in part from the organization of multitendoned finger muscles, and in part from distributed neural control of the hand.
A reconfigurable tactile display based on polymer MEMS technology (2008)

This research focuses on the development of polymer microfabrication technologies for the realization of two major components of a pneumatic tactile display: a microactuator array and a complementary microvalve (control) array. The concept, fabrication, and characterization of a kinematically-stabilized polymeric microbubble actuator (¡°endoskeletal microbubble actuator¡±) were presented. A systematic design and modeling procedure was carried out to generate an optimized geometry of the corrugated diaphragm to satisfy membrane deflection, force, and stability requirements set forth by the tactile display goals.\nA refreshable Braille cell as a tactile display prototype has been developed based on a 2x3 endoskeletal microbubble array and an array of commercial valves. The prototype can provide both a static display (which meets the displacement and force requirement of a Braille display) and vibratory tactile sensations. Along with the above capabilities, the device was designed to meet the criteria of lightness and compactness to permit portable operation. The design is scalable with respect to the number of tactile actuators while still being simple to fabricate.\nIn order to further reduce the size and cost of the tactile display, a microvalve array can be integrated into the tactile display system to control the pneumatic fluid that actuates the microbubble actuator. A piezoelectrically-driven and hydraulically-amplified polymer microvalve has been designed, fabricated, and tested. An incompressible elastomer was used as a solid hydraulic medium to convert the small axial displacement of a piezoelectric actuator into a large valve head stroke while maintaining a large blocking force. The function of the microvalve as an on-off switch for a pneumatic microbubble tactile actuator was demonstrated. To further reduce the cost of the microvalve, a laterally-stacked multilayer PZT actuator has been fabricated using diced PZT multilayer, high aspect ratio SU-8 photolithography, and molding of electrically conductive polymer composite electrodes.
The Sperry Symposium and the New Testament (2007)

Research Article| January 01 2007 The Sperry Symposium and the New Testament Review of Frank F. Judd Jr. and Gaye Strathearn, eds. Sperry Symposium Classics: The New Testament. Provo, UT: BYU Religious Studies Center; Salt Lake City: Deseret Book, 2006. viii + 423 pp., with index. $24.95.Review of Kent P. Jackson and Frank F. Judd Jr., eds. How the New Testament Came to Be: The 35th Annual Brigham Young University Sidney B. Sperry Symposium. Provo, UT: BYU Religious Studies Center; Salt Lake City: Deseret Book, 2006. ix + 334 pp., with index. $24.95. Kevin L. Barney Kevin L. Barney Kevin L. Barney studied classics at Brigham Young University (BA 1982) before earning law degrees at the University of Illinois (JD 1985) and DePaul University (1990). With John H. Jenkins and John A. Tvedtnes, he wrote Footnotes to the New Testament for Latter-day Saints, a two-volume set of explanatory notes to the Authorized Version of the New Testament. He practices public finance law with Kutak Rock LLP in Chicago. Search for other works by this author on: This Site Google The FARMS Review (2007) 19 (2007) (2): 177–191. https://doi.org/10.5406/farmsreview.19.2.0177 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Kevin L. Barney; The Sperry Symposium and the New Testament. The FARMS Review 1 January 2007; 19 (2007) (2): 177–191. doi: https://doi.org/10.5406/farmsreview.19.2.0177 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveUniversity of Illinois PressMormon Studies Review Search Advanced Search The text of this article is only available as a PDF. Copyright 2007 by the Board of Trustees of the University of Illinois2007 Article PDF first page preview Close Modal You do not currently have access to this content.
“WRITTEN BY HIMSELF”: A MANUSCRIPT LETTER OF OLAUDAH EQUIANO (1968)

“WRITTEN BY HIMSELF”: A MANUSCRIPT LETTER OF OLAUDAH EQUIANO Get access PAUL EDWARDS PAUL EDWARDS University of Edinburgh Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume 15, Issue 6, June 1968, Pages 222–225, https://doi.org/10.1093/nq/15-6-222 Published: 01 June 1968
Upregulation of the Tissue Inhibitor of Metalloproteinase-1 Protein Is Associated With Progression of Human Non–Small-Cell Lung Cancer (2004)

These results suggest that TIMP-1, independent of its inhibiting activity of MMPs, may have other function(s) critical for NSCLCs. The significance of our results is two-fold. The adverse outcome in patients with overexpression of TIMP-1 indicates its potential prognostic value in NSCLC. Thus, TIMP-1 overexpression may serve to help identify patients with particularly aggressive disease for adjuvant treatments. In addition, the TIMP-1 molecule may represent a novel therapeutic target for treatment of some NSCLCs.
Debridement (2006)

After reading the article and taking the test, the reader should be able to: 1. Discuss the physiologic process of wound healing and the rationale for debridement. 2. Describe evidence-based indications for and methods of debridement.
Toxin-Antitoxin systems: their role in persistence, biofilm formation, and pathogenicity (2014)

One of the most pertinent recent outcomes of molecular microbiology efforts to understand bacterial behavior is the discovery of a wide range of toxin-antitoxin (TA) systems that are tightly controlling bacterial persistence. While TA systems were originally linked to control over the genetic material, for example plasmid maintenance, it is now clear that they are involved in essential cellular processes like replication, gene expression, and cell wall synthesis. Toxin activity is induced stochastically or after environmental stimuli, resulting in silencing of the above-mentioned biological processes and entry in a dormant state. In this minireview, we highlight the recent developments in research on these intriguing systems with a focus on their role in biofilms and in bacterial virulence. We discuss their potential as targets in antimicrobial drug discovery.