gebhart/patrepeval huggingface dataset:
Network management system using web services and service oriented architecture &amp;#8212;A case study (2006)

This paper presents the design and implementation of a north bound interface framework for a network management system using the Web services (WS) and service oriented architecture (SOA) technologies. The primary goal of this project is to build a consistent programmatic interface for the operations supported by individual network management stations in the network. By using the recommended framework, a unified, consistent configuration control across devices can be obtained. The framework would also allow development of intelligent service oriented network configuration systems. This paper provides the architecture and design of the system and tries to present the lessons learnt during the process of developing the architecture. It also attempts to provide directions on applicability of Web services for managing network devices. The authors have ascertained that Web services using SOAP/XML is suitable for building distributed network management applications. Once network equipment vendors start implementing the basic NETCONF specification and other similar standards using the Web service/service oriented architecture, more robust and consistent systems can be built - this paves the way for future research and implementation of advanced management systems
Effect of dielectric material tolerances on the performance of singly-fed circularly polarised stacked patch antennas (2004)

A method for the design of broadband circularly polarised (CP) patch antennas was recently proposed by the authors (Chung, K.L. and Mohan, A.S., IEEE Trans. Antennas and Propagat., vol.51, p.3239-48, 2003). Designs for both C- and Ku- band antennas made use of high permittivity materials as their grounded substrates. However, the high permittivity material suffers from a high tolerance (/spl sim/3%) in dielectric constant, making the design process more difficult. This work examines the substrate tolerance effects on the performance of the CP-EMCP antenna elements presented in the previous paper. The performance includes the input impedance characteristics (VSWR), impedance bandwidth (ZBW), antenna gain, axial ratio and axial-ratio bandwidth (ABW). Further, this paper supplements the information on the design of broadband CP-EMCP patch antennas that comprise hi-lo dielectric combinations. The tolerance effects in four extreme cases on the gain and impedance matching (VSWR) of both the C- and Ku-band designs are shown to be insignificant. However, these same effects are significant on the axial ratio and axial-ratio bandwidth in both designs. The tolerance in thickness of high permittivity materials causes a deterioration in the boresight axial ratio of singly-fed stacked patch antennas.
The Evolutionarily Conserved OsPRR Quintet: Rice Pseudo-Response Regulators Implicated in Circadian Rhythm (2003)

In Arabidopsis thaliana, a number of circadian-associated factors have been identified, including TOC1 (TIMING OF CAB EXPRESSION 1) that is believed to be a component of the central oscillator. TOC1 is a member of a small family of proteins, designated as ARABIDOPSIS PSEUDO-RESPONSE REGULATORS (APRR1/TOC1, APRR3, APRR5, APRR7, and APRR9). As demonstrated previously, these APRR1/TOC1 quintet members are crucial for a better understanding of the molecular links between circadian rhythms, control of flowering time through photoperiodic pathways, and also photosensory signal transduction in this dicotyledonous plant. In this respect, both the dicotyledonous (e.g. A. thaliana) and monocotyledonous (e.g. Oryza sativa) plants might share the evolutionarily conserved molecular mechanism underlying the circadian rhythm. Based on such an assumption, and as the main objective of this study, we asked the question of whether rice also has a set of pseudo-response regulators, and if so, whether or not they are associated with the circadian rhythm. Here we showed that rice has five members of the OsPRR family (Oryza sativa Pseudo-Response Regulator), and also that the expressions of these OsPRR genes are under the control of circadian rhythm. They are expressed in a diurnal and sequential manner in the order of OsPRR73 (OsPRR37)-->OsPRR95 (OsPRR59)-->OsPRR1, which is reminiscent of the circadian waves of the APRR1/TOC1 quintet in A. thaliana. These and other results of this study suggested that the OsPRR quintet, including the ortholog of APRR1/TOC1, might play important roles within, or close to, the circadian clock of rice.
Comparisons of the Molecular Forms of Activated Bovine Factor X (1973)

Abstract Preparations of bovine Factor X zymogen were converted to enzymatically active forms with Russell's viper venom, with 25% sodium citrate, with a water-insoluble copoly-(maleic acid-ethylene)trypsin, with tissue factor (rabbit brain extract thromboplastin), and with a preparation designed to represent the intrinsic pathway of blood coagulation. The activated Factor X generated in each case was purified by chromatography on diethylaminoethylcellulose. Analytical ultracentrifugation, gel filtration, disc electrophoresis, sodium dodecyl sulfate-acrylamide electrophoresis, amino acid and carbohydrate analyses, carboxyl- and amino-terminal amino acid analyses, and peptide mapping of tryptic digests were used to show the striking molecular similarities of the enzymatically active products. Mixtures containing various combinations of the differently activated Factor X preparations behaved essentially as single species in disc electrophoresis, and after reduction with mercaptoethanol only two bands appeared in sodium dodecyl sulfate-acrylamide electrophoresis, as with each separate product. It was concluded that the diverse activation procedures yield essentially the same molecular form of activated Factor X.
Anatomy-performance correlation in Ti-based contact metallizations on AlGaN∕GaN heterostructures (2007)

A comprehensive study of the electrical and surface microstructural characteristics of Ti∕Au, Ti∕Al∕Au, Ti∕Mo∕Au, and Ti∕Al∕metal∕Au schemes, where metal is Ir, Mo, Nb, Pt, Ni, Ta, and Ti, has been carried out to determine the role of constituent components of multilayer contact metallizations on Ohmic contact formation on AlGaN∕GaN heterostructures. Attempts have been made to elucidate the anatomy (composition–structure) performance correlation in these schemes. Evidences have been obtained for the necessity of the Al and metal barrier layer as well as an optimal amount of Ti for achieving low-resistance Ohmic contact formation. A strong dependence of electrical properties and intermetallic interactions on the type of metal barrier layer used was found. Scanning electron microscopy characterization, coupled with energy dispersive x-ray spectroscopy, has shown evidence for alloy aggregation, metal layer fragmentation, Al–Au solid solution formation, and possible Au and/or Al reaction with metal layer. Results from the present study provide insights on the active and the necessary role various components of a multilayer contact metallization play for obtaining excellent Ohmic contact formation in the fabrication of AlGaN∕GaN high electron mobility transistors.
1.57 GHz asynchronous and 1.4 GHz dual-modulus 1.2 μm CMOS prescalers (2002)

We have implemented a dual-modulus prescaler dividing either by 64/65 (128/129) in a 1.2 /spl mu/m standard CMOS process. Using advanced dynamic circuit techniques a maximum frequency of 1.4 GHz has been measured at a supply of 5 V and 6.9 mA. An asynchronous prescaler dividing by 16 has also been implemented. The measured maximum input frequency is 1.57 GHz at a supply of 5 V and only 3 mA.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Spectroscopic Investigation of Group-III Acceptor States in Silicon (1967)

The excitation spectra associated with the group-III acceptor impurities; boron, aluminum, gallium, and indium in silicon, have been studied at low temperatures using grating spectrometers. The behavior of these spectra under uniaxial stress has been studied employing polarized radiation. The improved resolution of the present investigation has revealed details not reported previously for the zero-stress spectra. The line reported by earlier workers at 68.26 meV for gallium impurity has been resolved into three components at 67.95, 68.25, and 68.43 meV. For aluminum and indium impurity, the lines at 64.99 and 150.88 meV, respectively, have each been resolved into two components, at 64.96 and 65.16 meV and at 150.80 and 151.08 meV, respectively. The presence of the shoulder at 39.91 meV on the excitation line of boron at 39.64 meV has been confirmed. Also, transitions from the ground state associated with the ${p}_{\frac{3}{2}}$ valence band to excited states associated with the split-off ${p}_{\frac{1}{2}}$ valence band have been observed for gallium and indium impurity, in addition to those of boron and aluminum reported previously. It has been established that the ground state has ${\ensuremath{\Gamma}}_{8}$ symmetry for all the impurities studied. The first three excited states participating in the optical transitions (corresponding to lines 1-3) also have ${\ensuremath{\Gamma}}_{8}$ symmetry. The behavior of the line-4 complex under stress is consistent with the final states being ${\ensuremath{\Gamma}}_{6}+{\ensuremath{\Gamma}}_{7}+{\ensuremath{\Gamma}}_{8}$. The stress-induced sublevels of the ${\ensuremath{\Gamma}}_{8}$ final states of lines 1 and 2 have opposite ordering for compression along $〈111〉$. The various states of a given impurity differ in their quantitative response to stress. Also, there are marked differences in the quantitative stress behavior of these states from impurity to impurity.
LOWERING THE COST OF DOING BUSINESS THROUGH ADR (1997)

SUBTITLE: SOME OF THE LARGEST EXPENDITURES ASSOCIATED WITH DOING BUSINESS COME FROM HANDLING DISPUTES -- ATTORNEY FEES, FILING AND COURT COSTS AND TIME SPENT IN THE COURTROOM INSTEAD OF THE OFFICE: HOWEVER, ALTERNATIVE METHODS OF RESOLVING DISPUTES CAN SIGNIFICANTLY CUT THESE COSTS.
The role of angiotensin II in the regulation of breast cancer cell adhesion and invasion (2006)

As breast cancer remains the most common cause of cancer death in women, there is a continuing need not only to further characterise the processes of cancer progression, but also to improve accuracy of prognostic markers. Breast epithelial cells express components of the renin angiotensin system and studies suggest that these may be altered in disease progression. In addition, altered integrin expression correlates with lymph node metastasis. The aim of this study was to investigate the relationship between angiotensin II (AII) and integrins in breast tissue and, in particular, their role in breast cancer cell metastasis. Using in vitro assays, AII (10(-6) M)-treated MCF-7 and T47D breast cancer cells both show reduced adhesion to extracellular matrix proteins collagen-, fibronectin- and laminin-coated wells (P<0.001) and reduced invasion through collagen-, fibronectin- and laminin-coated membranes (P<0.05). This action was inhibited by co-treatment with the angiotensin type 1 receptor (AT1R) antagonist losartan (10(-5) M). The addition of the AT2R inhibitor PD123319 (10(-5) M) to AII-treated cells had no significant effect. Semi-quantitative reverse transcriptase-PCR and western blotting revealed that cells treated with AII (10(-6) M) expressed lower levels of both integrin alpha3 and beta1. Using specific inhibitors, this was shown to occur through protein kinase C signalling. These data suggest that AII reduces cell adhesion and invasion through the type 1 receptor and that this effect may be due to reduced expression of integrins, and in particular alpha3 and beta1.
Physical performance attributes of junior and senior women, juvenile, junior, and senior men judokas. (1991)

The purpose of this study was to describe the physical performance abilities of high level, developing Juvenile men and Junior and Senior men and women judokas. The subjects were 17 women and 43 men identified as members of the 1989 Alberta Judo Team by the Alberta Kodokan Black Belt Association. Physical characteristics and performance abilities were assessed through a battery of tests which included: height, weight and skinfold thickness; static strength (grips, arms, back, and total (TST)); flexibility (trunk forward flexion (TF)); maximum aerobic power (VO2max) (treadmill run); and upper body maximal anaerobic power (PP) and capacity (MP) (upper body Wingate test). Physical performance abilities were not different between the Junior and Senior women and substantially better than normative values for untrained women. Combined values (+/- SD) for Junior and Senior women were: VO2max 44.45 (3.56) ml/kg.min; PP 342.68 (76.92) w; MP 234.99 (46.62) w; TF 39.77 (6.39) cm; TST 127.91 (20.95) kg. The physical performance abilities of the Juvenile men: VO2max 57.62 (3.42) ml/kg.min; PP 406.89 (171.55) w; MP 281.68 (113.42) w; TF 39.35 (6.89) cm; TST 164.63 (51.07) kg; were superior to those of similarly aged, untrained young men, but comparable to those reported for trained adolescent athletes. The Junior men's physical performance abilities: VO2max 59.26 (3.95) ml/kg.min; PP 573.13 (116.83) w; MP 395.12 (61.95) w; TF 39.00 (4.39) cm; TST 221.60 (30.24) kg; were not different from the Senior men's, except for relative maximum oxygen uptake, and generally better than those values reported for other Junior judokas and Junior athletes in some other sports. The Senior men's physical performance abilities: VO2max 53.75 (5.57) ml/kg.min; PP 674.50 (133.26) w; MP 447.85 (87.19) w; TF 38.06 (8.86) cm; TST 223.37 (46.15) kg, were comparable with those reported for other developing, high level Senior judokas, but lower than the values reported for elite judokas competing internationally. These data support the position that successful participation in judo by high level, developing athletes is dependent upon appropriate levels of technical skill supported by above average endurance capacity, upper body anaerobic power and capacity, static strength, and flexibility.
Mitral valve repair for ischemic mitral regurgitation: lessons from the Cardiothoracic Surgical Trials Network randomized study. (2016)

Approximately 30% to 50% of patients will develop ischemic mitral regurgitation (MR) after a myocardial infarction, which is a result of progressive left ventricular remodeling and dysfunction of the subvalvular apparatus, and portends a poor long-term prognosis. Surgical treatment is centered on mitral valve repair utilizing a restrictive annuloplasty, or valve replacement with preservation of the subvalvular apparatus. In the recent Cardiothoracic Surgical Trials Network (CSTN) study, patients with severe ischemic MR were randomized to mitral valve repair with a restrictive annuloplasty versus chordal-sparing valve replacement, and concomitant coronary artery bypass grafting, if indicated. At 2-year follow-up, mitral valve repair was associated with a significantly higher incidence of moderate or greater recurrent MR and heart failure, with no difference in the indices of left ventricular reverse remodeling, as compared with valve replacement. The current appraisal aims to provide insight into the CSTN trial results, and discusses the evidence supporting a pathophysiologic-guided repair strategy incorporating combined annuloplasty and subvalvular repair techniques to optimize the outcomes of mitral valve repair in ischemic MR.
Inversion of magnetotelluric data in a sparse model domain (2016)

The inversion of magnetotelluric data into subsurface electrical conductivity poses an ill-posed problem. Smoothing constraints are widely employed to estimate a regularized solution. Here, we present an alternative inversion scheme that estimates a sparse representation of the model in a wavelet basis. The objective of the inversion is to determine the few non-zero wavelet coefficients which are required to fit the data. This approach falls into the class of sparsity constrained inversion schemes and minimizes the combination of the data misfit in a least-squares &ell;<inf>2</inf> sense and of a model coefficient norm in an &ell;<inf>1</inf> sense (&ell;<inf>2</inf>-&ell;<inf>1</inf> minimization). The &ell;<inf>1</inf> coefficient norm renders the solution sparse in a suitable representation such as the multiresolution wavelet basis, but does not impose explicit structural penalties on the model as it is the case for &ell;<inf>2</inf> regularization. The presented numerical algorithm solves the mixed &ell;<inf>2</inf>-&ell;<inf>1</inf> norm minimization problem for the nonlinear magnetotelluric inverse problem. We demonstrate the feasibility of our algorithm on synthetic 2-D MT data as well as on a real data example. We found that sparse models can be estimated by inversion and that the spatial distribution of non-vanishing coefficients indicates regions in the model which are resolved.
Immune-based Therapy Clinical Trials in Hepatocellular Carcinoma (2015)

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality and continues to increase. Current standard of care for patients with HCC only provides limited therapeutic benefit. Development of innovative strategies is urgently needed. Experience with immunotherapy in HCC is quite early, but rapidly rise in the recent 15 years. Multifaceted immune-based approaches have shown efficacy in achieving disease regression, representing the most promising new treatment approach. Here, we classify the ongoing or completed clinical trials in HCC in terms of the immune strategies to be used and assess their clinical outcomes. The generated information may be helpful in the design of future immune-based therapies for achieving ideal tumor control and maximizing anti-tumor immunity.
New Definitions for Sepsis and Septic Shock (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GM-CSF Autoantibodies and Neutrophil Dysfunction in Pulmonary Alveolar Proteinosis (2007)

The antimicrobial functions of neutrophils are impaired in patients with pulmonary alveolar proteinosis, owing to the presence of GM-CSF autoantibodies. The effects of these autoantibodies show that GM-CSF is an essential regulator of neutrophil functions.
Functional properties of native and cheese whey protein concentrate powders (2007)

The objective of this study was to compare microfiltered native whey protein concentrate and traditional cheese whey protein concentrate powders and their functional properties. Solubility, viscosity, gelation, foaming properties, emulsification and water‐holding capacity were studied. The effect of spray and freeze drying methods on functional properties was evaluated. Gel strength varied from 0.11 to 0.65 N. Foaming stability and overrun varied from 0 to 29.3 min and from 230 to 2200%, respectively. Foaming and gelation properties were clearly better with native whey protein powders. Differences between drying methods were not observed but higher heat load decreased solubility.
Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3 (2016)

The major human complement regulator in blood, complement factor H (FH), has several closely related proteins, called FH-related (FHR) proteins. As all FHRs lack relevant complement regulatory activity, their physiological role is not well understood. FHR protein 3 (FHR-3) has been suggested to compete with FH for binding to Neisseria meningitidis, thereby affecting complement-mediated clearance. Clearly, the in vivo outcome of such competition greatly depends on the FH and FHR-3 concentrations. While FH levels have been established, accurate FHR-3 levels were never unequivocally reported to date. Moreover, CFHR3 gene copy numbers commonly vary, which may impact the FHR-3 concentration. Hence, we generated five anti-FHR-3 mAbs to specifically measure FHR-3 in human healthy donors of which we determined the gene copy number variation at the CFH/CFHR locus. Finally, we examined the acute-phase response characteristics of FHR-3 in a small sepsis cohort. We determined FHR-3 levels to have a mean of 19 nM and that under normal conditions the copy number of CFHR3 correlates to a very large extent with the FHR-3 serum levels. On average, FHR-3 was 132-fold lower compared to the FH concentration in the same serum samples and FHR-3 did not behave as a major acute phase response protein.
Rat‐Liver Cholesterol 7α‐Hydroxylase (1975)

A new assay is described to measure the activity of cholesterol 7alpha-hydroxylase and compared to the conventional 14C method used by other investigators. This method is based on the mechanism of the enzymic hydroxylation, i.e. a direct and stereospecific substitution of the 7alpha-hydrogen by a hydroxyl group. [7alpha-3H]Cholesterol is incubated at 37 degrees C and in the presence of molecular O2, in a medium buffered by postassium phosphate at pH 7.4 and containing liver microsomes (or 9000 X g supernatant), NADPH, MgCl2 and cysteamine. Tween-80 (1.5 mg/ml) is used to introduce enough substrate (300 muM) in the incubation mixture to saturate the enzyme (Km = 100 muM). Under these conditions the tritiated water released into the incubation medium reflects accurately the enzymic activity. The results obtained with this method are similar to the one obtained with a [4-14C]cholesterol technique (r = 0.96; P less than 0.001). The main advantage of the [7alpha-3H]cholesterol method is a complete independence from further metabolism of the first enzymic product, the 7alpha-hydroxycholesterol, the tritiated water representing the entire cholesterol 7alpha-hydroxylase activity.