gebhart/patrepeval huggingface dataset:
Is bran efficacious in irritable bowel syndrome? A double blind placebo controlled crossover study. (1987)

Twenty eight patients with classical irritable bowel syndrome completed a double blind placebo controlled crossover trial in which they added to their normal diet a daily supplement of either 12 bran biscuits (1 = 1.3 g fibre) or 12 placebo biscuits (1 = 0.23 g fibre). Each biscuit was given for three months in random order with crossover to the alternative biscuit at three months. After the initial three months therapy, there was a significant symptomatic improvement compared with pretreatment in both the bran treated (p less than 0.01) and placebo treated groups (p less than 0.01), but there was no significant difference in symptom scores between these two groups. There was no further improvement in either group after the second three months treatment with the alternative therapy. When crossover data for all 28 subjects were combined, symptoms scores after three months bran therapy and after three months placebo therapy did not differ significantly. Twenty four patients completed three day stool collections in both treatment periods. When the symptomatic response to bran among 15 subjects in whom stool weights rose on bran was compared with that among nine subjects whose stool weights were static or fell on the bran, it was shown that symptomatic improvement was independent of an increase in stool weight. These data suggest that in irritable bowel syndrome, especially that associated with abdominal pain, the beneficial effects of bran are due to a placebo response which is independent of an increase in stool weight.
Aircraft position prediction using neural networks (2005)

Thesis (M. Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.
An anchoring theory of lightness perception. (1999)

A review of the field of lightness perception from Helmholtz to the present shows the most adequate theories of lightness perception to be the intrinsic image models. Nevertheless, these models fail on 2 important counts: They contain no anchoring rule, and they fail to account for the pattern of errors in surface lightness. Recent work on both the anchoring problem and the problem of errors has produced a new model of lightness perception, one that is qualitatively different from the intrinsic image models. The new model, which is based on a combination of local and global anchoring of lightness values, appears to provide an unprecedented account of a wide range of empirical results, both classical and recent, especially the pattern of errors. It provides a unified account of both illumination-dependent failures of constancy and background-dependent failures of constancy, resolving a number of long-standing puzzles.
Development of Thin Film Ceramic Thermocouples for High Temperature Environments (2004)

The maximum use temperature of noble metal thin film thermocouples of 1100 C (2000 F) may not be adequate for use on components in the increasingly harsh conditions of advanced aircraft and next generation launch technology. Ceramic-based thermocouples are known for their high stability and robustness at temperatures exceeding 1500 C, but are typically found in the form of rods or probes. NASA Glenn Research Center is investigating the feasibility of ceramics as thin film thermocouples for extremely high temperature applications to take advantage of the stability and robustness of ceramics and the non-intrusiveness of thin films. This paper will discuss the current state of development in this effort.
Graph R-CNN for Scene Graph Generation (2018)

We propose a novel scene graph generation model called Graph R-CNN, that is both effective and efficient at detecting objects and their relations in images. Our model contains a Relation Proposal Network (RePN) that efficiently deals with the quadratic number of potential relations between objects in an image. We also propose an attentional Graph Convolutional Network (aGCN) that effectively captures contextual information between objects and relations. Finally, we introduce a new evaluation metric that is more holistic and realistic than existing metrics. We report state-of-the-art performance on scene graph generation as evaluated using both existing and our proposed metrics.
Psychiatric comorbidity and suicidality among intravenous drug users. (1992)

Rates of alcoholism, depression, and antisocial personality disorder, but not other psychiatric disorders (other than drug dependence), are significantly elevated in intravenous drug users. Moreover, among drug users, the decision to inject is differentially made by those with antisocial personality disorder. A history of suicide attempt is common among intravenous drug users, but injecting appears to convey little additional risk above substantial but non-intravenous drug use.
Real-time string search engine LSI for 800-Mbit/sec LANs (2003)

A string search engine for real-time address filtering (SSEAF) LSI is developed for 800-Mb/s local area networks (LANs). The SSEAF LSI contains a 16-kb (64-bit*256-word) content-addressable memory (CAM) which can store 256 workstation addresses. Simultaneously carried out within 80 ns in the CAM are both a comparison of a 64-bit destination address in an incoming data bucket with 256 stored addresses and the generation of any matched addresses. About 243 K MOSFETs are integrated on an 8.36-mm*8.5-mm chip using a double-metal 1.3- mu m CMOS fabrication process.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Description of the leukocyte function-associated antigen 1 (LFA-1 or CD11a) promoter. (1993)

The CD11a/CD18 (leukocyte function-associated antigen 1 or LFA-1) leukocyte integrin is expressed at high levels on the cell surface of T lymphocytes and macrophages, where it mediates homotypic and heterotypic adherence between leukocytes and other cell types by binding to intracellular adhesion molecules 1 and 2 on the conjugate cell. To initiate studies of the molecular regulation of expression of the CD11a molecule, we isolated genomic clones corresponding to the 5'-flanking region of CD11a, identified the transcriptional start sites for CD11a, and characterized the CD11a promoter sequence in transient expression assays. The CD11a promoter (1.7 kb) directed functional activity of a heterologous reporter gene in the T-lymphocyte cell line Jurkat and the myeloid cell line HL-60 but did not direct functional activity in three different nonleukocyte cell lines. Deletional analysis of the CD11a promoter sequence indicated the presence of distinct, cell-type-specific regulatory sequences with the region from -40 to -17 relative to the transcription start sites responsible for most of the in vitro activity of the CD11a promoter in the Jurkat T-cell line, and the promoter sequence located within the first 17 bp relative to the transcription start sites responsible for CD11a promoter activity in the HL-60 cell line. Identification of the CD11a promoter provides the opportunity to identify unique cis-acting elements and trans-acting factors responsible for the cell-type-specific expression of CD11a in human leukocytes. Further, the CD11a promoter may be useful in transgenic constructs and in retroviral vectors to direct expression of heterologous genes selectively in leukocytes.
Tempering for Bayesian C&RT (2005)

This paper concerns the experimental assessment of tempering as a technique for improving Bayesian inference for C&RT models. Full Bayesian inference requires the computation of a posterior over all possible trees. Since exact computation is not possible Markov chain Monte Carlo (MCMC) methods are used to produce an approximation. C&RT posteriors have many local modes: tempering aims to prevent the Markov chain getting stuck in these modes. Our results show that a clear improvement is achieved using tempering.
High therapeutic potential of Spilanthes acmella: A review. (2013)

Spilanthes acmella, a well known antitoothache plant with high medicinal usages, has been recognized as an important medicinal plant and has an increasingly high demand worldwide. From its traditional uses in health care and food, extensive phytochemical studies have been reported. This review provides an overview and general description of the plant species, bioactive metabolites and important pharmacological activities including the preparation, purification and in vitro large-scale production. Structure-activity relationships of the bioactive compounds have been discussed. Considering data from the literature, it could be demonstrated that S. acmella possesses diverse bioactive properties and immense utilization in medicine, health care, cosmetics and as health supplements. As a health food, it is enriched with high therapeutic value with high potential for further development.
The wheat resistance gene <i>Lr34</i> results in the constitutive induction of multiple defense pathways in transgenic barley (2015)

The wheat gene Lr34 encodes an ABCG-type transporter which provides durable resistance against multiple pathogens. Lr34 is functional as a transgene in barley, but its mode of action has remained largely unknown both in wheat and barley. Here we studied gene expression in uninfected barley lines transgenic for Lr34. Genes from multiple defense pathways contributing to basal and inducible disease resistance were constitutively active in seedlings and mature leaves. In addition, the hormones jasmonic acid and salicylic acid were induced to high levels, and increased levels of lignin as well as hordatines were observed. These results demonstrate a strong, constitutive re-programming of metabolism by Lr34. The resistant Lr34 allele (Lr34res) encodes a protein that differs by two amino acid polymorphisms from the susceptible Lr34sus allele. The deletion of a single phenylalanine residue in Lr34sus was sufficient to induce the characteristic Lr34-based responses. Combination of Lr34res and Lr34sus in the same plant resulted in a reduction of Lr34res expression by 8- to 20-fold when the low-expressing Lr34res line BG8 was used as a parent. Crosses with the high-expressing Lr34res line BG9 resulted in an increase of Lr34sus expression by 13- to 16-fold in progenies that inherited both alleles. These results indicate an interaction of the two Lr34 alleles on the transcriptional level. Reduction of Lr34res expression in BG8 crosses reduced the negative pleiotropic effects of Lr34res on barley growth and vigor without compromising disease resistance, suggesting that transgenic combination of Lr34res and Lr34sus can result in agronomically useful resistance.
Immobilization of enzymes on polypropylene bead surfaces by anhydrous ammonia gaseous plasma technique (1988)

Anhydrous ammonia gaseous plasma technique was used for the surface modification of polypropylene beads. Amino groups were added onto the surfaces of beads by exposing them to ammonia plasma. Through these amino groups covalent immobilization of glucose oxidase and peroxidase were carried out. The total amounts of immobilized glucose oxidase and immobilized peroxidase were found to be 52 and 43 micrograms/cm2, respectively. To assess the stability of enzyme-polypropylene linkage, beads with covalently immobilized glucose oxidase and peroxidase were washed with phosphate buffer. It was found that after the removal of the adsorbed enzymes, the concentration of covalently immobilized enzymes tended to reach a steady state. After additional washing with buffer for 5 to 6 h, 40-55% of the immobilized enzymes were found to be in the active form.
Reduced scattering coefficient determination by non-contact oblique angle illumination: methodological considerations (2007)

The reduced scattering coefficient, &mgr;<sub>s</sub>, was determined using oblique angle illumination and imaging backscattered light intensity. The distance &Dgr;r between the point of light incidence (hot-spot) and the circular symmetric diffuse reflectance centre, is ∼1/&mgr;<sub>s</sub><sup>'</sup>. Previously, &Dgr;r was obtained analyzing a 1D strip aligned with the laser beam. We improved this method by calculating a 2D intensity image with extended dynamic range by assessing camera linearity, superimposing images with multiple integration times, and compensating for lens vignetting. The hot-spot algorithm utilises several images to minimize speckle variations and account for laser beam shape. Diffuse centre position is obtained by filtering the superimposed image with decreasing thresholds using momentum analysis to determine circular symmetry. The method was evaluated on 18 optical liquid phantoms with &mgr;<sub>s</sub>&egr;[1.5, 3.0] mm<sup>-1</sup> and &mgr;<sub>s</sub>&egr;[0.01, 0.16] mm<sup>-1</sup>. The 2D method had better linearity with &mgr;<sub>s</sub> and smaller variations due to more stable hot-spot detection, than the 1D method. The anisotropy factor <i>g</i> was obtained by fitting measured and Monte Carlo simulated spatially resolved intensity decays and verified with a laser Doppler flowmetry technique. With an optimal compensation for the &mgr;<sub>a</sub> dependence, the rms error in &mgr;<sub>s</sub><sup>'</sup> estimation was 2.9%.
Nuevas localidades fosilíferas en la cordillera central de colombia (1962)

Si descrivono nuove località fossilifere della Cordigliera Centrale. I fossili raccolti appartengono all' Aptiano ed all' Albiano medio. Tra i due piani é stata riconosciuta per la prima volta nella Cordigliera Centrale una importante discordanza (già nota nella Orientale), indizio di una importante fase tettonica con la quale é connessa la messa in posto della dioriti quarzifere delbatolite circumpacifico.
Antitumor Effects of Clinical Dosing Regimens of Bisphosphonates in Experimental Breast Cancer Bone Metastasis (2007)

Bisphosphonates exhibit direct antitumor activity in animal models, but only at high doses that are incompatible with the clinical dosing regimens approved for the treatment of cancer patients with skeletal metastases. We compared the antitumor effects of clinical dosing regimens of the bisphosphonates zoledronic acid and clodronate in a mouse model of bone metastasis.
Predicting Mortality in African Americans With Type 2 Diabetes Mellitus: Soluble Urokinase Plasminogen Activator Receptor, Coronary Artery Calcium, and High‐Sensitivity C‐Reactive Protein (2018)

In African Americans with type 2 diabetes mellitus, suPAR was strongly associated with mortality and improved risk discrimination metrics beyond traditional risk factors, CAC and hs-CRP. Studies addressing the clinical usefulness of measuring suPAR concentrations are warranted.
<i>Acoustics of American English Speech</i> (1994)

Share Icon Share Twitter Facebook Reddit LinkedIn Reprints and Permissions Cite Icon Cite Search Site Citation Joseph P. Olive, Alice Greenwood, John Coleman, Thomas D. Rossing; Acoustics of American English Speech. Physics Today 1 March 1994; 47 (3): 59–60. https://doi.org/10.1063/1.2808444 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentPhysics Today Search Advanced Search
[The Freiburg Vision Test. A computer-assisted procedure with sequential strategy]. (1993)

Single Landolt Cs were presented in one of four positions on a monitor. Subjects responded by pressing one of four buttons (forced choice). A computer selected the size of the Landolt Cs on a logarithmic scale using the "Best PEST" algorithm (Best Parameter Estimation by Sequential Testing), a modern procedure to measure psychophysical thresholds. For comparison, conventional measurements according to DIN 58220 (Deutsche Industrie Norm) were performed with Landolt Cs projected in eight positions, using three out of five correct responses as the threshold criterion. Examination of 23 patients (most of them with senile cataract) did not show any significant difference between the two tests in either visual acuity or reproducibility on two consecutive days. The coefficients of variation between sessions were 22% for the Freiburg test and 26% for the DIN test and 18% between the two tests, pooled over two sessions. The Freiburg acuity test thus appears to be numerically equivalent to the DIN 58220 procedure. In addition, it has a number of advantages: (1) examiner-dependent variability is reduced; therefore, the test can be used by inexperienced examiners; (2) the forced choice technique is used rigorously; (3) mistakes in confounding oblique directions are largely avoided; (4) the procedure is about twice as fast.
Current views on the pharmacological properties of the immunomodulator, lobenzarit disodium. (1997)

Lobenzarit disodium (LBZ) is an immunomodulator and antioxidative drug developed and used successfully in Japan for the treatment of rheumatoid arthritis (RA). Studies in animals and humans have shown striking differences between the pharmacological profile of LBZ and nonsteroidal antiinflammatory drugs commonly used in the treatment of RA. LBZ does not inhibit the biosynthesis of prostaglandins and leukotrienes and is ineffective on acute inflammatory reactions induced in animals. Therefore, its usefulness in RA is ascribed to immunopharmacological properties of the drug. Currently, evidence is available that B- and T-lymphocytes are targets of LBZ's actions which regulates the functions of these cells. LBZ reduces IgE titers in serum of sensitized mice by activating suppressor T-lymphocytes and inhibiting anaphylactic shock induced by ovalbumin. These results provide evidence in favor of the potential use of LBZ in the treatment of allergic diseases, which must be elucidated in controlled double-blind clinical trials. The suppressive effects of LBZ on the function of activated B cells as well as in the production of anti-DNA antibody have been reported. These findings suggest that LBZ may be effective in the treatment of other autoimmune diseases such as lupus erythematosus that are also characterized by the production of autoantibodies from activated B cells. Recently, an open clinical trial in patients with systemic lupus erythematosus supports this point of view. Other potential therapeutic uses of LBZ are in autoimmune-related diabetes and in autoimmune liver disease which are documented in this review. LBZ also selectively antagonizes the contractile responses of isolated rabbit aorta strips induced by thromboxane A2-mimetic U-46619. This result provides evidence in favor of an antagonist of LBZ at the level of TxA2 receptors and supports the potential usefulness of LBZ in some cardiovascular disorders such as cardiopulmonary diseases and thrombosis. LBZ is a scavenger of oxygen-free radicals such as hydroxyl radicals, superoxide, peroxyl and singlet oxygen. This property contributes substantially to its pharmacological and therapeutic profile as well as its mechanism of action.
On the application of the microgenetic algorithm to the design of broad-band microwave absorbers comprising frequency-selective surfaces embedded in multilayered dielectric media (2001)

In this paper, we present a procedure for synthesizing broad-band microwave absorbers incorporating frequency-selective surface (FSS) screens embedded in dielectric media using a binary coded genetic algorithm (GA). The GA simultaneously and optimally chooses the material in each layer, thickness of each layer, FSS screen periodicity in the z- and y-directions, its placement within the dielectric composite, and the FSS screen material. Additionally, the GA generates the cell structure of the FSS screen. The result is a multilayer composite that provides maximum absorption of both TE and TM waves for a prescribed range of frequencies and incident angles. This technique automatically places an upper bound on the total thickness of the composite.
Synthesis of C2 and Cs symmetric zinc complexes supported by bis(phosphinimino)methyl ligands and their use in ring opening polymerisation catalysis (2002)

Synthetic routes to zinc complexes supported by sterically demanding bis(phosphinimino)methyl ligands are reported. Two aryl-substituted ligand precursors have been utilised, [CH2(Ph2PNC6H2Me3-2,4,6)2], 1, and [CH2(Ph2PNPh)(Ph2PNC6H2Me3-2,4,6)], 2. The second of these is the first example of an asymmetric bis(phosphinimino)methane. These ligands are converted to three-coordinate RZnX complexes (R = 1; X = Me, N(SiMe3)2; R = 2; X = Me) with either C2 or Cs symmetry in solution by reaction with either ZnMe2 or Zn[N(SiMe3)2]2 in toluene. All three derivatives have been shown to exist as three-coordinate monomers in the solid state by X-ray diffraction analysis. Protonolysis of these compounds with the bulky phenol 2,4-tBu2C6H3OH or triphenylmethanol resulted in the isolation of a series of three-coordinate aryloxy or alkoxyzinc derivatives. In contrast, reaction with less sterically demanding alcohols resulted in protonation of the bis(phosphinimino)methyl ligand. A similar result was obtained from reaction of RZnMe (R = 1) and triphenylsilanol and the product is the first example of a bis(triorganosiloxy)zinc compound to be structurally characterised. All the compounds have been examined for activity in ring opening polymerisation catalysis of rac-lactide. The aryloxy and triphenylmethoxy derivatives are active catalysts; however, no evidence of true ‘living’ behaviour or stereocontrol of diastereomer insertion has been observed.
Deriving Generalized Means as Least Squares and Maximum Likelihood Estimates (1992)

Functions called generalized means are of interest in statistics because they are simple to compute, have intuitive appeal, and can serve as reasonable parameter estimates.The well-known arithmetic, geometric, and harmonic means are all examples of generalized means.We show how generalized means can be derived in a unified way, as least squares estimates for a transformed data set.We also investigate models that have generalized means as their maximum likelihood estimates.
A multi-resolution scheme ICP algorithm for fast shape registration (2003)

The iterative closest point (ICP) algorithm is widely used for the registration of geometric data. One of its main drawbacks is its quadratic time complexity O(N/sup 2/) with the shape number of points N, which implies long processing time, especially when using high resolution data. This paper proposes to accelerate the process by a coarse to fine multiresolution approach in which a solution at a coarse level is successively improved at a finer level of representation. Specifically, it investigates this multiresolution ICP approach when coupled with the tree search or the neighbor search closest point algorithms. A theoretical and practical analysis and a comparison of the considered algorithms are presented. Confirming the success of the multiresolution scheme, the results also show that this combination permits us to create a very fast ICP algorithm, gaining speed up to a factor of 27 over a standard fast ICP algorithm.
Magnetic resonance angiography in the head and neck. (1986)

Magnetic resonance angiography (MRA) provides a means to visualize vessel structure without the use of contrast agents and consequently without the risks and discomfort associated with contrast media. We have developed a flow encoding procedure which exploits the spatial dependence in the phase of spin magnetization generated by a gradient pulse. This technique yields image information for only those spins having macroscopic motion (i.e. flowing blood). Excellent suppression of non-moving spins can be obtained despite the overwhelming abundance of stationary spins. Data are presented in a projection format similar to that of traditional subtraction angiography.