gebhart/patrepeval huggingface dataset:
Development of a Low Temperature Sol-Gel-Derived Titania-Silica Implant Coating (2010)

Objective of this study was to develope low temperature sol-gel coatings for shape memory metal (NiTi) and evaluate their biocompatibility on NiTi suture material. A series of low temperature TiO2 and TiO2-SiO2 sol-gel coatings were prepared on glass substrates. The silica content of TiO2-SiO2 coatings ranged from 0 to 30 mol%. The coatings were also prepared with polyethyleneglycol (PEG). The contact angle and photocatalytic activity measurements were used to evaluate the surface properties of the coatings. Stability of the coatings was tested in simulated body fluid (SBF). The TiO2-SiO2 90/10 film made with PEG was more hydrophilic, showed photocatalytic activity and was crack-free after the SBF test, thus it was chosen to animal experiment as a new experimental coating. Uncoated NiTi suture and the suture coated with high temperature TiO2 were used as reference materials. NiTi sutures were inserted subcutaneously on the back of rat for four weeks. In routine histological examinations all materials showed good biocompatibility with mild inflammatory cell reaction. No significant differences in the soft tissue response among the materials were observed. Both the high and new low temperature processed sol-gel coatings remained attached on the sutures confirming the suitability of the coating technique on thin NiTi sutures.
ISOLATION OF <i>ASPERGILLUS PARASITICUS</i> SPEARE AND <i>BEAUVERIA BASSIANA</i> (BALS.) VUILLEMIN FROM MELANOPLINE GRASSHOPPERS (ORTHOPTERA: ACRIDIDAE) AND DEMONSTRATION OF THEIR PATHOGENICITY IN <i>MELANOPLUS SANGUINIPES</i> (FABRICIUS) (1988)

Abstract Aspergillus parasiticus Speare and Beauveria bassiana (Bals.) Vuillemin were isolated from melanopline grasshoppers in Saskatchewan in 1986 and 1987. The pathogenicity of these isolates for Melanoplus sanguinipes (Fabricius) nymphs was assessed by topical, oral, and injected applications of 1.0 × 10 3 , 10 4 , or 10 5 conidia per individual. The A . parasiticus isolate was pathogenic to M . sanguinipes by injection and topical application but not orally. The B . bassiana isolate was pathogenic when injected or topically applied resulting in high mortality (82–100%), at all doses tested, between days 3 and 5 post-inoculation. Beauveria bassiana was infectious, at the highest dose tested, when orally applied with the majority of mortality occurring between 7 and 14 days post-inoculation.
Semi-synthetic data set generation for security software evaluation (2014)

Threats to modern ICT systems are rapidly changing these days. Organizations are not mainly concerned about virus infestation, but increasingly need to deal with targeted attacks. This kind of attacks are specifically designed to stay below the radar of standard ICT security systems. As a consequence, vendors have begun to ship self-learning intrusion detection systems with sophisticated heuristic detection engines. While these approaches are promising to relax the serious security situation, one of the main challenges is the proper evaluation of such systems under realistic conditions during development and before roll-out. Especially the wide variety of configuration settings makes it hard to find the optimal setup for a specific infrastructure. However, extensive testing in a live environment is not only cumbersome but usually also impacts daily business. In this paper, we therefore introduce an approach of an evaluation setup that consists of virtual components, which imitate real systems and human user interactions as close as possible to produce system events, network flows and logging data of complex ICT service environments. This data is a key prerequisite for the evaluation of modern intrusion detection and prevention systems. With these generated data sets, a system's detection performance can be accurately rated and tuned for very specific settings.
Building Effective Multivendor Autonomic Computing Systems (2006)

At the 3rd IEEE International Conference on Autonomic Computing (ICAC 2006), we organized a panel that discussed the feasibility of building effective multivendor autonomic computing systems. The panelists provided a variety of viewpoints on these topics from both industry and academic perspectives
Anomalous Double Cyclization Reactions of .beta.-Formylporphyrins (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnomalous Double Cyclization Reactions of .beta.-FormylporphyrinsLaurent Barloy, David Dolphin, Daniel Dupre, and Tilak P. WijesekeraCite this: J. Org. Chem. 1994, 59, 26, 7976–7985Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/jo00105a011https://doi.org/10.1021/jo00105a011research-articleACS PublicationsRequest reuse permissionsArticle Views487Altmetric-Citations77LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A molecular-capsular-type prediction system for 90 Streptococcus pneumoniae serotypes using partial cpsA-cpsB sequencing and wzy- or wzx-specific PCR (2005)

In a previous study, a molecular capsular type (MCT) prediction system for 51 Streptococcus pneumoniae serotypes was developed based on a combination of partial cpsA-cpsB sequencing and serotype(s)/group(s)-specific PCR. In this study, another 169 S. pneumoniae isolates were added to the existing database of 427 isolates, including representatives of all 39 serotypes not previously studied. In addition to the authors' own limited sequence data for all 90 serotypes, cpsA-cpsB sequence data published by the S. pneumoniae capsular loci-sequencing group (http://www.sanger.ac.uk/Projects/S_pneumoniae/CPS/) at the Sanger Institute or available from GenBank were incorporated into the database. All serotypes, except 25A, were represented by at least two isolates. The number of sequence types identified was 138, of which 110 corresponded to single conventional serotypes (CSs); of these, 57 were represented by two or more isolates. Twenty-six sequence types were shared by between two and four CSs. To resolve these shared cpsA-cpsB sequence types and increase the discriminatory power of our system, the genes encoding the capsular polysaccharide flippase (wzx) and polymerase (wzy) were annotated and 24 new serotype(s)/group(s)-specific PCRs targeting wzy and two targeting wzx were designed. Using both cpsA-cpsB sequencing and wzx/wzy PCR, MCT correctly predicted the CSs of 516 (73 %) and the serogroup of an additional 155 (22 %) of the 708 isolates evaluated. For 5 % of isolates, MCT could not distinguish between members of five serotype pairs (37 isolates) containing members of different serogroups. Although further study of the relationship between MCT and CS is needed, this system now allows serotype or serogroup identification of 95 % of S. pneumoniae isolates.
A Novel Method of Distal End-Tidal CO2 Capnography in Intubated Infants: Comparison With Arterial CO2 and With Proximal Mainstream End-Tidal CO2 (2008)

Distal end-tidal CO2 measured via a double-lumen endotracheal tube was found to have good correlation and agreement with PaCO2, remained reliable in conditions of severe lung disease, and was more accurate than the standard mainstream proximal end-tidal CO2.
Synthesis of Clickable Coating Polymers by Postpolymerization Modification: Applications in Microarray Technology (2016)

In this paper, we report on the postpolymerization modification (PPM) of a polymer to introduce new functionalities that enable click chemistry reactions for microarray applications. The parent polymer, named copoly(DMA-NAS-MAPS), is composed of N,N-dimethylacrylamide (DMA), a monomer that self-adsorbs onto different materials through weak interactions such as hydrogen bonding or van der Waals forces, 3-(trimethoxysilyl)propyl methacrylate (MAPS) that strengthens the stability of the coating through the formation of covalent bonds with siloxane groups on the surface to be coated, and N-acryloyloxysuccinimide (NAS), an active ester group, highly reactive toward nucleophiles, which enables bioprobe immobilization. This copolymer has been widely exploited to coat surfaces for microarray applications but exhibits some limitations because of the potential hydrolysis of the active ester (NHS ester). The degradation of the NHS ester hampers the use of this coating in some situations, for example, when probe immobilization cannot be accomplished through a microspotting situation, but in large volumes, for example, in microchannel derivatization or micro-/nanoparticle functionalization. To overcome the limitations of NHS esters, we have developed a family of polymers that originate from the common copolymer precursor, by reacting the active ester contained in the polymer chain with a bifunctional amine. In particular, the functional groups introduced in the polymer using PPM enable click chemistry reactions such as azide/alkyne or thiol/maleimide "click" reactions, with suitably modified biomolecules. The advantages of such reactions are quantitative yields, orthogonality of functional groups, and insensitivity of the reaction to pH. The new click functionalities, inserted with quantitative yields, improve the stability of the coating, enabling the attachment of biomolecules directly from a solution and avoiding the spotting of reduced volumes (pL) of probes. Finally, we have demonstrated the applicability of the click surfaces in a highly effective solid-phase PCR for the genotyping of the G12D KRAS mutation.
Electrical and electronic properties of polymers : a state-of-the-art compendium (1988)

Acetylenic Polymers Diacetylene Polymers Electrically Conducting Polymers Electrical Properties Electromagnetic Interference Electronics Applications Electrooptical Applications Lithographic Resists Optical Properties Photoconductive Polymers.
Interferon-β is a key regulator of proinflammatory events in experimental autoimmune encephalomyelitis (2010)

Background: Interferon (IFN)-β is an effective therapy for relapsing-remitting multiple sclerosis, yet its mechanism of action remains ill-defined. Objectives: Our objective was to characterize the role of IFN-β in immune regulation in experimental autoimmune encephalomyelitis (EAE). Methods: IFN-β +/+ and IFN-β —/— mice were immunized with myelin oligodendrocyte glycoprotein peptide in the presence or absence of IFN-β, to induce EAE. Disease pathogenesis was monitored in the context of incidence, time of onset, clinical score, and immune cell activation in the brains, spleens and lymph nodes of affected mice. Results: Compared with IFN-β +/+ mice, IFN-β —/ — mice exhibited an earlier onset and a more rapid progression of EAE, increased numbers of CD11b + leukocytes infiltrating affected brains and an increased percentage of Th17 cells in the central nervous system and draining lymph nodes. IFN-β treatment delayed disease onset and reduced disease severity. Ex vivo experiments revealed that the lack of IFN-β results in enhanced generation of autoreactive T cells, a likely consequence of the absence of IFN-β-regulated events in both the CD4 + T cells and antigen-presenting dendritic cells. Gene expression analysis of IFN-β-treated bone marrow macrophages (CD11b + ) identified modulation of genes affecting T cell proliferation and Th17 differentiation. Conclusions: We conclude that IFN-β acts to suppress the generation of autoimmune-inducing Th17 cells during the development of disease as well as modulating pro-inflammatory mediators.
A Meta-Top-Down Method for Large-Scale Hierarchical Classification (2013)

Recent large-scale hierarchical classification tasks typically have tens of thousands of classes on which the most widely used approach to multiclass classification--one-versus-rest--becomes intractable due to computational complexity. The top-down methods are usually adopted instead, but they are less accurate because of the so-called error-propagation problem in their classifying phase. To address this problem, this paper proposes a meta-top-down method that employs metaclassification to enhance the normal top-down classifying procedure. The proposed method is first analyzed theoretically on complexity and accuracy, and then applied to five real-world large-scale data sets. The experimental results indicate that the classification accuracy is largely improved, while the increased time costs are smaller than most of the existing approaches.
Deep levels caused by misfit dislocations in GaAsSb/GaAs heterostructures (1995)

Two deep electron traps induced by lattice mismatch in relaxed GaAs1−xSbx layers (x=0% to 3%) grown by liquid phase epitaxy (LPE) on GaAs substrates have been revealed by means of deep-level transient spectroscopy. One of the traps, that shows nonstandard, logarithmic capture kinetics and whose energy level is tied to the valence-band edge, has been related to electron states associated with α dislocations. The other trap has been attributed to the EL2 defect and possible reasons of its unexpected formation in the LPE-grown layers are briefly discussed.
Mixed mobile ion effect in fluorozincate glasses (2005)

The mixed mobile ion effect has been investigated for the first time in zinc fluoride glasses where in addition to alkali cations fluorine anions also participate in the diffusion process, unlike mixed alkali oxide glasses. The minimum in the conductivity, conductivity relaxation frequency, crossover frequency and decoupling index indicates the existence of the mixed mobile ion effect in these fluoride glasses. It has been observed that the non-exponential parameter and the frequency exponent are independent of temperature. It has been established that alkali ions and fluorine anions exhibit lower dimensionality of the conduction pathways in mixed alkali zinc fluoride glasses than that in the single alkali lithium based zinc fluoride glasses while they are migrating. From the scaling of the conductivity spectra, it has been established that the relaxation dynamics in mixed alkali zinc fluoride glasses is independent of temperature and composition.
[Tourette syndrome. New aspects on pharmacological treatment]. (1989)

Tourette syndrome is now widely accepted as a neurological disorder characterized by chronic multiple tics and uncontrollable sounds. The exact etiology of Tourette syndrome is still unknown, although an organic etiology is suspected. Hypotheses of the pathophysiologic mechanism of Tourette syndrome have generally included a component of neurotransmitter system "imbalance". Dopaminergic, cholinergic, serotoninergic, noradrenergic and peptidergic neurotransmitters have all been proposed as components of this "imbalance". The two most utilized agents, haloperidol and pimozide, decrease central dopaminergic activity by blocking dopamine receptors and have been shown to improve the symptomatology of Tourette syndrome. However, adverse effects limit their usefulness and new drugs that have fewer adverse effects and greater efficacy are needed. Some of the new therapeutic agents evaluated in Tourette syndrome are mentioned. The purpose of this paper is to provide physicians with guidelines for the pharmacological treatment of Tourette syndrome, based on the present available literature.
<title>Mid-infrared spectroscopy as a tool for disease pattern recognition from human blood</title> (1998)

Disease pattern recognition (DPR) is being developed as a reagent-free measurement technique for the diagnosis of blood samples. The technological basis of this method is mid IR spectroscopy. For the analysis, 1 (mu) l blood is deposited on a disposable and dried before measurement. The IR spectra give rise to characteristic patterns in narrow wavenumber regions, which are modified in the presence of relatively small pathophysiological changes. the spectral changes depending on the disease are always higher than those caused by the deviations resulting from instrumental or handling errors. The information content of the spectra is reflected by the standard error, which varies between differently 'diseased' and 'healthy' persons. The standard error of the first derivative spectra is three times higher for 'diseased' compared to 'healthy' persons. This has been demonstrated for a comparable population of 'diseased' and 'healthy' persons. In total, more than 2000 spectra from different individuals were analyzed. Preliminary result using various mathematical algorithms indicate, that clear distinctions can be found for a variety of different disease compared to patterns of 'healthy' spectra. This qualitative information about the blood sample may be used as a quick and comprehensive diagnostic tool.
Enzyme and Transition-Metal-Complex Catalyzed Synthesis of Polyphenols with Pendant Oligo(<i>p</i>-phenylene) and Their Optical, Electrochemical, and Thermal Properties (2009)

Horseradish peroxidaze (HRP)-catalyzed polymerization of 4-hydroxy[1,1′;4′,1′′]terphenyl (MonoPh(3)OH), 4-bromo-4′-hydroxybiphenyl (MonoBrPh(2)OH), and 4-bromo-4′′-hydroxy[1,1′;4′,1′′]terphenyl (MonoBrPh(3)OH) caused oxidative coupling at the hydroxyphenyl group to yield polyphenols with a pendant oligo-p-phenylene (OPP): PolyPh(3)OH and PolyBrPh(m)OH (m = 2 and 3; m − 1 denotes the number of pendant benzene rings). Polyphenols with a longer OPP chains (PolyPh(m)OH; m = 4 and 5) were obtained through the Pd-complex catalyzed reaction of PolyBrPh(m)OH (m = 2 and 3) with 4-biphenylboronic acid. The Pd-complex-catalyzed polymerization of 3,5-dibromo-4-methoxy[1,1′;4′,1′′]terphenyl or 3,5-dibromo-4-octyloxy[1,1′;4′,1′′;4′′,1′′′]quaterphenyl with 9,9-dihexylfluorene-2,7-diboronic acid bis(1,3-propanediol) ester or 2,5-dioctyloxybenzene-1,4-diboronic acid yielded polyphenylenes PolyPh(m)OMeFlu (m = 3 and 4) and PolyPh(3)OMePh, respectively, and hydrolysis of the methyl group provided polyphenylenes with the phenolic OH groups PolyPh(3)OHFlu and PolyPh(3)OHPh, respectively. Deprotonation of the OH group of the polyphenols with the pendant OPP obtained by the treatment with NaH caused a bathochromic shift of absorption maxima (λmax's) of the polymers. The bathochromic shift of the deprotonated species PolyPh(m)ONa (m = 3, 4, and 5), PolyPh(3)ONaFlu, and PolyPh(3)ONaPh increased with an increase in the donor numbers (DNs) of the solvents. PolyPh(m)OH (m = 3, 4, and 5), PolyPh(3)OHFlu, and PolyPh(3)OHPh were photoluminescent (PL) in solution. The emission peak positions of PolyPh(m)OH and PolyPh(m)ONa depended on the DNs of the solvents; that is, the emission colors could be tuned by changing the solvent. The polymers were electrochemically active in film.
Microstructural Evolution During Solidification of Al-Fe-Ce Powders (1985)

Al-Fe-Ce alloys produced from gas atomized powders exhibit greater strength at 150°-315°C than conventional aluminum alloys. This higher strength can be attributed to small dispersoids that form during the rapid solidification and precipitates that form after solidification and during consolidation. Understanding the powder microstructure is essential to establishing the relationship between wrought product microstructures and properties. Microstructures present in Al-8 wt% Fe-4 wt% Ce and Al-7 wt% Fe-6 wt% Ce powders (-325 mesh) are presented; in addition, a solidification sequence for atomized droplets is proposed. Analyses include: SEM, TEM, and Chemical Analyses from thin foils via EDXS. Powder samples were compacted into wafers at 200 ksi and subsequently electropolished via the window technique.
Impact of magnetic isolation on pointing system performance in the presence of structural flexibility (1985)

The inertial pointing stability of a gimbal pointing system (AGS) was compared with a magnetic pointing/gimbal followup system (ASPS), under certain conditions of system structural flexibility and disturbance inputs from the gimbal support structure. Separate 3 degree-of-freedom (3DOF) linear models based on NASTRAN modal flexibility data for the gimbal and support structures were generated for the ASPS configurations. Using the models inertial pointing control loops providing 6dB of gain margin and 45 deg of phase margin were defined for each configuration. The pointing loop bandwidth obtained for the ASPS is more than twice the level achieved for the AGS configuration. The AGS limit is attributed to the gimbal and support structure flexibility. As a result of the higher ASPS pointing loop bandwidth and the disturbance rejection provided by the magnetic isolation ASPS pointing performane is significantly better than that of the AGS system. The low frequency peak of the ASPS transfer function from base disturbance to payload angular motion is almost 60dB lower than AGS low frequency peak.
Q-DNN: A quality-aware deep neural network for blind assessment of enhanced images (2016)

Image enhancement is widely popular due to its capability of producing "better" visual quality for specific applications. Although many enhancement algorithms have been developed in recent years, the studies towards blind assessment of enhanced images are still very lacking. In this paper, we propose a data-driven blind image quality assessment (BIQA) method based on the quality-aware deep neural network (Q-DNN). Unlike the conventional hand-crafted features designed for measuring the degradation level of specific distortion types, a supervised learning model is utilized in our Q-DNN, which is capable of adaptively updating the feature extractor and quality regressor for describing the visual artifacts caused by different image enhancement tasks. Experimental results on two challenging enhanced image databases show that the proposed method is significantly superior to the state-of-the-art BIQA metrics.
Deterioration of depth measurements due to interference of multiple RGB-D sensors (2014)

Depth sensors based on projected structured light have become standard in robotics research. However, when several of these sensors share the same workspace, the measurement quality can deteriorate significantly due to interference of the projected light patterns. We present a comprehensive study of this effect in Kinect and Xtion RGB-D sensors. In particular, our study investigates the effect of measurement failure due to interference. Our experiments show that up to 95% of the depth measurements in the interference image region can disappear when two RGB-D sensors interfere with each other. We determine the severity of interference as a function of relative sensor placement and propose simple guidelines to reduce the impact of sensor interference. We show that these guidelines greatly increase the robustness of RGB-D-based SLAM.