gebhart/patrepeval huggingface dataset:
Fabrication of Maraging Steels by Metal Injection Molding Process. (1995)

The unique combinations of high toughness and high strength available with the maraging steels have made them desirable for structural applications. However, it was very difficult to produce the high performance maraging steels by conventional powder metallurgy (P/M) processes because of hard material. Metal Injection Molding (MIM) process alleviates the need for secondary working operations because of providing the net shape components, which is a suitable production route for hard materials. In this paper, the characteristics of debinding, sintering and aging behavior were studied for injection molded maraging steel compacts, and also the mechanical properties were investigated by tensile and impact test . The results are summarized as follows: 1) By using the continuous process which went on through thermal debinding and sintering at 1623K for 3.6ks in hydrogen atmosphere, the compacts were considerably densified to a relative density of 96% .
Non-Orthogonal Multiple Access (NOMA) for 5G Systems (2017)

Radio access technologies for cellular communications are characterized by multipleaccess schemes whose purpose is to serve multiple users with limited bandwidth resources. Typical examples of multiple access schemes are frequency division multiple access (FDMA), time division multiple access (TDMA), code division multiple access (CDMA), and orthogonal frequency division multiple access (OFDMA). In the history of mobile communications, multiple access schemes have been widely investigated in various types of cellular networks, from the first generation (1G) to the fourth generation (4G). Specifically, the FDMA scheme was used in the 1G system, the TDMA scheme was employed in the second generation (2G) systems, CDMA was the dominant multiple access scheme in the third generation (3G) systems, and the OFDMA scheme has been widely used in 4G systems. In many conventional multiple access schemes, such as TDMA and OFDMA, different users are allocated to orthogonal resources in either the time or the frequency domain in order to alleviate interuser interference. However, the spectral efficiency of these orthogonal multiple access (OMA) schemes is low, since bandwidth resources occupied by users with poor channel conditions cannot be shared by others. As a result, these OMA schemes are not sufficient to handle the explosive growth in data traffic in the mobile Internet of the fifth generation (5G) networks. On the other hand, the chip rates of a CDMA system need to be much higher than the information data rates, which means that the use of CDMA in 5G is also potentially problematic owing to the ultra-high data rates expected in 5G systems. Consequently, in 5G networks, new, sophisticated multiple access technologies are needed to support massive connectivity for a very large number of mobile users and/or Internet of Things (IoT) devices with diverse quality-of-service (QoS) requirements [1]. Multiple access in 5G mobile networks is an emerging and challenging research topic, since it needs to provide massive connectivity, large system throughput and small latency simultaneously [2, 3]. Among the promising candidates for 5G multiple access, NOMA has received considerable attention in particular [4–7]. In contrast to conventional OMA, NOMA can accommodate user fairness via non-orthogonal resource allocation and, therefore, is also expected to increase the system throughput.
Semantics-Enabled Service Discovery Framework in the SIMDAT Pharma Grid (2008)

We present the design and implementation of a semantics-enabled service discovery framework in the data Grids for process and product development using numerical simulation and knowledge discovery (SIMDAT) Pharma Grid, an industry-oriented Grid environment for integrating thousands of Grid-enabled biological data services and analysis services. The framework consists of three major components: the Web ontology language (OWL)-description logic (DL)-based biological domain ontology, OWL Web service ontology (OWL-S)-based service annotation, and semantic matchmaker based on the ontology reasoning. Built upon the framework, workflow technologies are extensively exploited in the SIMDAT to assist biologists in (semi)automatically performing in silico experiments. We present a typical usage scenario through the case study of a biological workflow: IXodus.
Effects of geldanamycin on signaling through activator-protein 1 in hypoxic HT29 human colon adenocarcinoma cells. (1999)

One of the characteristic responses of HT29 human colon adenocarcinoma cells to hypoxic stress is the induction of c-jun expression and binding to the activator-protein 1 (AP-1) element. To study the mechanism of c-jun activation during hypoxia, inhibitors of signaling pathways leading to the activation of AP-1 transcription factor were used. One of them, the benzoquinone ansamycin geldanamycin (GA) Mr-90,000 heat-shock protein (hsp90)-binding antibiotic, is known to disrupt signaling pathways by inducing destabilization of the enzyme complexes and degradation of signaling intermediates involving the proteasome. In our experiments, GA inhibited both basal and hypoxia-induced c-jun expression (IC50 = 75 nM). GA also abolished the hypoxia-induced increase in c-Jun NH2-terminal kinase (JNK1) catalytic activity and demonstrated an inhibitory effect on stress-activated protein kinase/ERK kinase-1 (SEK1); other participants in the mitogen-activated protein kinase and p38 signal transduction pathways were not affected to the same degree. GA treatment led to a decrease in the nuclear content of c-Jun but not that of c-Fos or of activating transcription factor 2. Functional consequences of these effects were suggested by the inhibition of AP-1 binding in hypoxic HT29 cells in the presence of GA. Pretreatment with the proteasome inhibitor lactacystin before the addition of GA resulted in the elevation of overall c-jun level, but it was unable to restore the hypoxia-induced c-jun expression. Our results demonstrate that GA acts as a highly potent inhibitor of hypoxia-induced c-jun expression, affecting the activation of JNK and of the AP-1 transcription factor. However, the effect of GA cannot be attributed solely to the inhibition of signaling through JNK, and additional mechanisms remain to be identified.
Vertical P-MOSFETs with heterojunction between source/drain and channel (2002)

The growth of high quality strained SiGe-Si and SiGeC-Si heterostructures allows incorporation of band gap engineering into Si technology, which can be used to improve device characteristics. A heterojunction MOSFET (HJMOSFET) structure has been proposed in which the large valence band offset at SiGe-Si heterojunctions reduces the punchthrough and DIBL for P-MOSFETs (Hareland et al, 1993). Vertical MOSFETs allow more freedom in terms of band gap engineering, and the channel length is not limited by the lithography (Liu et al, 1998). In this paper, we show experimentally that the heterojunction at the source can be used to suppress the floating body effect and short channel effect. Vertical P-MOSFETs with strained SiGe and SiGeC sources have been fabricated with 60-75 nm effective channel lengths. The electrical characteristics of the devices are compared with those of control Si devices and with simulation results.
BlueMall (2008)

Recently, research for context-aware systems has risen significantly. New social needs require the use of brand new technology to build rich ubiquitous computing spaces. Such spaces allow users to use services without being aware of any interaction with the system. For such an important and dedicated task, some context awareness is needed so computers, based on their environment, can react accordingly. Advertising on mobile devices is one of this new needs and has demonstrated to have a large potential due to the very personal and intimate nature of the devices and the possibility of reaching a broad range of targets. In this paper we present BlueMall, a context-aware pervasive system for advertising in large commercial areas. BlueMall uses Java and Bluetooth wireless technology making it a very portable system. We describe the overall architecture and discuss the implementation steps taken to build our application. To evaluate the performance behavior of our system in relation to the environment, we run some experiments in our testbed. Experimental results show that the system provides a viable solution for permission-based mobile advertising.
Virtualizing the VAX architecture (1991)

Thk paper describes modifications to the VAX arcKltecture to support virtual machhtes. The VAX arc~ltecture contains several instructions that are sensitive but not privileged. It is also the first architecture with more than two protection rings to support virtual machines. A technique for mapping four virtual rings onto three physical rings, employing both software and microcode, is described. Differences between the modified and standard VAX architectures are presented, along with a description of the virtual VAX computer.
A contradição político-pedagógica dos Pré-Vestibulares Populares frente às políticas de ações afirmativas (2010)

Dentro de um cenário em que o vestibular passa cada vez mais a sofrer críticas pelo caráter excludente das camadas mais populares da juventude, faz-se necessário refletir sobre o posicionamento político-pedagógico dos pré-vestibulares populares (PVP’s), em especial frente às políticas de ações afirmativas. Fenômeno de ocorrência nacional principalmente a partir dos anos 90, os PVP’s, espaços que utilizam os conteúdos exigidos nos vestibulares como fator de mobilização de milhares de pessoas interessadas no ingresso ao ensino superior, são projetados por concepções político-pedagógicas contraditórias. Pelo menos dois posicionamentos projetam a importância dos PVP’s: por um lado, são entendidos como política pública que pode contribuir para democratizar o ingresso no ensino superior; de outro, atuariam como movimento social, e nessa qualidade devem pressionar o Estado para que ele construa políticas públicas de democratização do acesso ao ensino superior, dentre elas a política de cotas étnico-sociais. Para além de situar o debate a respeito da implementação do programa de ações afirmativas, o objetivo desse artigo é contribuir para o desafio da mudança de concepções pela qual passa a universidade brasileira, marcadamente no último qüinqüênio.
ChemInform Abstract: RESOLUTION OF Γ‐METHYL AND Γ‐FLUOROGLUTAMIC ACIDS. LACK OF STEREOSPECIFICITY OF LEUCINE AMINOPEPTIDASE WITH L‐LEUCYL‐L‐ERYTHRO‐Γ‐SUBSTITUTED GLUTAMATES (1984)

Abstract Durch Hydrolyse in′ Gegenwart von Leucinaminopeptidase gehen aus L‐ Leucyl‐DL‐(threo + erythroyy‐X‐glutamaten neben den D‐threo‐ und den D‐erythro‐y‐X‐Glutamaten die optisch reinen L‐threo‐ und die L‐erythro‐Isomeren hervor, deren optische Reinheit überraschend nur 70 bzw. 87% beträgt (X: ‐CH, bzw. X: ‐F).
A Visual Analytics Approach for Peak‐Preserving Prediction of Large Seasonal Time Series (2011)

Abstract Time series prediction methods are used on a daily basis by analysts for making important decisions. Most of these methods use some variant of moving averages to reduce the number of data points before prediction. However, to reach a good prediction in certain applications (e.g., power consumption time series in data centers) it is important to preserve peaks and their patterns. In this paper, we introduce automated peak‐preserving smoothing and prediction algorithms, enabling a reliable long term prediction for seasonal data, and combine them with an advanced visual interface: (1) using high resolution cell‐based time series to explore seasonal patterns, (2) adding new visual interaction techniques (multi‐scaling, slider, and brushing & linking) to incorporate human expert knowledge, and (3) providing both new visual accuracy color indicators for validating the predicted results and certainty bands communicating the uncertainty of the prediction. We have integrated these techniques into a well‐fitted solution to support the prediction process, and applied and evaluated the approach to predict both power consumption and server utilization in data centers with 70–80% accuracy.
Increase in the Concentration of Carbon 18 Monounsaturated Fatty Acids in the Liver with Hepatitis C: Analysis in Transgenic Mice and Humans (2001)

Steatosis is one of the histologic characteristics of chronic hepatitis C and is well reproduced in a transgenic mouse model for hepatocellular carcinoma (HCC) in which the core protein of hepatitis C virus (HCV) plays a pivotal role in inducing steatosis and HCC. In the present study, the lipid composition in the liver of the HCV core gene transgenic mice as well as in those of chronic hepatitis C patients was determined. The concentration of carbon 18 monounsaturated (C18:1) fatty acids, such as oleic and vaccenic acids, which are known to increase membrane fluidity leading to higher cell division rates, significantly increased in the livers of transgenic mice compared to nontransgenic control mice. The concentration of C18:1 fatty acids also significantly increased in the livers of chronic hepatitis C patients compared to subjects without HCV infection. These results suggest that HCV may affect a specific pathway in the lipid metabolism and cause steatosis in the liver.
Standards for <i>Clostridium chauvoei</i> vaccine—The relationship between the response of guinea pigs and sheep following vaccination and challenge with virulent <i>C. chauvoei</i> (1986)

Twelve commercial 5-component clostridial vaccines with known variations in potency of the blackleg (Clostridium chauvoei) component, were simultaneously tested in sheep and guinea pigs. Controlled challenge experiments provided evidence of a highly significant correlation in the response of the 2 species. The guinea pig laboratory model is considered to be a valid indicator of field performance for vaccines containing blackleg antigen.
Bifunctional Organocatalyst for Activation of Carbon Dioxide and Epoxide To Produce Cyclic Carbonate: Betaine as a New Catalytic Motif (2010)

Bifunctional organocatalysts bearing an ammonium betaine framework have been developed as a new catalytic motif for the activation of carbon dioxide and epoxides to produce cyclic carbonates.
Anomalous Attractive Interactions in Polypropylene Blends (1997)

Some new results on thermodynamic interactions in blends of model polyolefins are reported, including more examples of the anomalous attraction found earlier for polyisobutylene (PIB) blends. Small-angle neutron scattering (SANS) data demonstrate a significant suppression of concentration fluctuations in two polypropylene (PP) blends, meaning a net attraction between components relative to the pure liquid states and corresponding to negative values of the Flory−Huggins interaction parameter χ. As in the PIB blends, the temperature dependencies indicate LCST phase behavior but with much higher critical temperatures for the PP blends. The two PP blends with net attraction also differ from PIB blends in that all their components behave conventionally (net repulsion, positive χ) in blends with other species. The other five PP blends in the study exhibit net repulsion but a wide range of mixing behavior, regular to highly irregular, depending on the second species.
P01.20 Treatment of recurrent glioblastoma with the cytokine inhibitor, ibudilast in combination with temozolomide (2017)

BACKGROUND: Recurrence in patients with glioblastoma (GBM) is inevitable, even in patients with O-6-Methylguanine-DNA Methyl Transferase (MGMT) methylation. We identified increased expression of the inflammatory cytokine, Macrophage Inhibitory Factor (MIF) and its receptor CD74 in patients with recurrent tumours. High levels of MIF and CD74 were associated with poor overall survival in GBM patients. This study aims to determine efficacy of Ibudliast (AV411; 3-isobutyryl-2-isopropylpyrazolo-[1,5-a]pyridine) to block MIF expression and decrease tumour burden. Ibudilast is an anti-inflammatory drug that was developed for the treatment of bronchial asthma. METHODS: The patient derived cell lines (PDCLs) RN1 (MGMT unmethylated), BAH1 (MGMT methylated), and HW1 (MGMT methylated) were treated in vitro with different concentrations of ibudilast in combination with temozolomide (TMZ). Patient derived xenograft (PDX) models of GBM were developed and treated with the combination of ibudilast and TMZ. Overall survival was calculated. Results: Regardless of MGMT status, significant synergism between ibudilast and TMZ was observed in the PDCLs. Efficacy was associated with significantly decreased expression of its targets, MIF and CD74. Downstream proteins such as Src and Akt were also significantly inhibited. The combination induced apoptosis. RN1 and HW1 tumors were established intracranially in Balb/c nude mice. Significant increases in survival times of the mice were recorded when treated with the combination. CONCLUSION: Ibudilast in combination with TMZ resulted in significant blockage of MIF expression, increased apoptosis and longer survival in vivo. A human pilot study for recurrent GBM patients is underway.
Evolution of nickel borides in Ni-Si-B brazed joints of nickel during post-braze heat treatment (1997)

In brazes of pure nickel with Ni-Si-B filler metals, nickel boride forms in the central region of the brazed gap by solidification, and in the pure nickel base metal along bothjointfaying surfaces by solid state diffusion and precipitation. During subsequent heat treatment, the gap boride gradually decomposes and dissolves, while the lining boride along the joint faying surfaces increases both in size and quantity. This phenomenon is the result of an uphill diffusion of boron from the brazed gap, which remains very much a ternary Ni-Si-B system, into the base metal, which is largely a binary Ni-B system owing to the rapid diffusion of boron ahead of silicon into the base metal. The driving force for such diffusion is the high chemical potential of boron in the gap owing to the presence of silicon, which substantially lowers the solubility of boron in y-Ni. On the other hand, the separation between the opposite lining boride layers increases with brazing time and is controlled by the diffusion of silicon from the gap into the base metal. The formation of lining boride in the base metal can be suppressed by suitable alloying elements, such as chromium, which can effectively retard the diffusion of boron.
Using Test Delegations from the Root Prior to Full Allocation and Delegation (2014)

The delegation of certain strings as generic Top Level Domains (gTLDs)
may cause stability and security issues if such strings have been used
in private environments prior to their delegation. Test delegations
can be used to enable empirical research on the extent of the
potential for name collision. This document describes one such
approach to an empirical testing framework for name collision, and
considers the applicability of this approach to detect other forms of
name collision.
An Interview with Myself About Story Theatre (1971)

Research Article| May 01 1971 An Interview with Myself About Story Theatre A. J. Antoon A. J. Antoon Search for other works by this author on: This Site Google Theater (1971) 3 (2): 76–78. https://doi.org/10.1215/00440167-3-2-76 Cite Icon Cite Share Icon Share Twitter Permissions Search Site Citation A. J. Antoon; An Interview with Myself About Story Theatre. Theater 1 May 1971; 3 (2): 76–78. doi: https://doi.org/10.1215/00440167-3-2-76 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsTheater Search Advanced Search The text of this article is only available as a PDF. Copyright © yale/theater 19711971 Article PDF first page preview Close Modal Issue Section: Story Theatre You do not currently have access to this content.
Large Momentum Beam Splitter Using Bloch Oscillations (2009)

The sensitivity of an inertial sensor based on an atomic interferometer is proportional to the velocity separation of atoms in the two arms of the interferometer. In this Letter we describe how Bloch oscillations can be used to increase this separation and to create a large momentum transfer (LMT) beam splitter. We experimentally demonstrate a separation of 10 recoil velocities. Light shifts during the acceleration introduce phase fluctuations which can reduce the fringes contrast. We precisely calculate this effect and demonstrate that it can be significantly reduced by using a suitable combination of LMT pulses. We finally show that this method seems to be very promising to realize a LMT beam splitter with several tens of recoils and a very good efficiency.
Amantadine prophylaxis during an institutional outbreak of type A (H1N1) influenza (1986)

• In January 1984, an outbreak of influenza caused by A/Victoria/7/83—like virus, a new H1N1 variant, occurred in an institution for mentally handicapped children and adults. During the first 18 days of the outbreak, 35 (81%) of 43 residents in two housing modules became ill, nearly all of whom had received influenza vaccine the previous autumn. Amantadine hydrochloride prophylaxis was initiated in two other housing modules and was continued for 28 days. While factors influencing the risk of introduction and secondary spread of influenza virus were comparable in all four modules, only ten (16%) of 63 residents who received amantadine were infected, only one of whom became symptomatic. Most side effects associated with amantadine were mild, but residents with active, preexisting major-motor seizure disorders demonstrated an increase in seizure activity compared with the previous eight-month period; those who took the maximum daily dose of amantadine hydrochloride (200 mg) and those who were also taking anticonvulsants other than phenobarbital were at highest risk. (<i>Arch Intern Med</i>1986;146:1751-1756)
Compiling Esterel into sequential code (2000)

Embedded real-time software systems often need fine-grained parallelism and precise control over time, things typical real-time operating systems do not provide. The Esterel language has both, but Existing compilers produce slow code for large programs.
Taxonomical implications of the emergence of high frequency of occurrence of 2,4-diamino-6,7-diisopropylpteridine-resistant strains of Vibrio cholerae from clinical cases of cholera in Calcutta, India (1992)

Of the 110 consecutive isolates of Vibrio cholerae recovered from cholera patients admitted to the Infectious Diseases Hospital, Calcutta, India, between July 1989 and October 1990, 90 and 82.7% were resistant to 10 and 150 micrograms of 2,4-diamino-6,7-diisopropylpteridine (O/129), respectively. Additionally, all O/129-resistant strains of V. cholerae were multiply resistant to antimicrobial agents. Except in the cases of four strains, resistance to O/129 was invariably linked with resistance to co-trimoxazole. Although O/129 susceptibility is still a useful test for Vibrio identification, resistance of V. cholerae to this compound in local areas might occasionally pose a problem.