gebhart/patrepeval huggingface dataset:
Oxide-based RRAM switching mechanism: A new ion-transport-recombination model (2008)

This paper presents a unified physical model to elucidate the resistive switching behavior of metal-oxide-based resistive random access memory (RRAM) devices using the ion-transport-recombination model. In this model, the rupture of conductive filaments is caused by recombination of oxygen ions and electron-low-occupied oxygen vacancies. The transport equations of interstitial oxygen ions in the oxide matrix are introduced to quantitatively investigate the reset speed and other properties such as uniformity, endurance, and reset current. The proposed mechanism was verified by experiments.
Radio-Ligand Binding Assay of Specific Estrogens Using a Soluble Uterine Macromolecule (1968)

Journal Article Radio-Ligand Binding Assay of Specific Estrogens Using a Soluble Uterine Macromolecule Get access STANLEY G. KORENMAN STANLEY G. KORENMAN 1Department of Medicine, Harbor General Hospital Torrance; UCLA School of Medicine Los Angeles, California Search for other works by this author on: Oxford Academic Google Scholar The Journal of Clinical Endocrinology & Metabolism, Volume 28, Issue 1, 1 January 1968, Pages 127–130, https://doi.org/10.1210/jcem-28-1-127 Published: 01 January 1968 Article history Received: 31 May 1967 Accepted: 26 September 1967 Published: 01 January 1968
Adoptive Immunotherapy of Murine Pulmonary Metastases with Interleukin 2 and Interferon-γ (1989)

We examined the activities of activated lymphocytes, interferon-gamma (IFN-gamma), and interleukin 2 (IL-2) in adoptive immunotherapy of pulmonary metastases. Pulmonary metastases produced in Balb/c mice by a single tail-vein injection of 5 X 10(5) murine sarcoma (MCB8) tumor cells on day 0 were treated with combinations of Con A-activated lymphocytes (CAL) (3 X 10(7) cells on days 3 and 7), IL-2 (5 X 10(4) U three times a day on days 3 to 8), and IFN-gamma (5 X 10(4) U/mouse on days 1 to 8). Treated tumors contained increased numbers of infiltrating Thy-1.2+ lymphocytes and a predominance of L3T4+(CD4+) lymphocytes. The level of expression of class I and class II MHC antigens by tumor cells in the lung was increased after treatment. Mice that received CAL + IL-2 + IFN-gamma showed approximately 80% reduction in tumor burden as compared to controls (P = 0.001). Mice treated with IL-2 + CAL, or IL-2 + IFN-gamma, displayed approximately 50% reduction (both P less than 0.02 as compared to triple therapy), whereas IL-2, IFN-gamma, or CAL administered as single agents had little effect on pulmonary metastases. We conclude that adoptive immunotherapy with activated lymphocytes and IL-2 is enhanced by IFN-gamma.
Neurofilament light chain serum levels reflect disease severity in MOG-Ab associated disorders (2019)

The identification of myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) in sera of subjects with inflammatory central nervous system (CNS) conditions has improved the differential diagnosis between multiple sclerosis (MS) and antibody-mediated demyelinating disorders.1 However, the heterogeneous clinical course of MOG-Ab-positive cases complicates outcome prediction. Cerebrospinal fluid (CSF) and serum neurofilament light chain (NfL) levels reliably predict disease activity in patients with clinically isolated syndrome and MS.2 

We assessed serum and CSF NfL concentration in patients with MOG-Ab-associated conditions according to clinical/paraclinical characteristics to investigate NfL as a biomarker of disease severity.

Between 2015 and 2018, we included 38 consecutive MOG-Ab-positive patients tested at our institution and 38 age-matched unaffected controls.

Clinical data at sampling and at last follow-up, MRI and CSF findings were collected in standardised case report forms. Brain/spinal cord MRIs were obtained within 2 months from blood drawn for MOG-Ab/NfL analysis and assessed by referring neurologists blinded to assay results.

Blood samples were collected, centrifuged and stored at −80°C. Presence of serum AQP4-Ab was analysed using a commercial cell-based assay (Euroimmun, Lubeck, Germany). Two independent investigators analysed MOG-Ab using recombinant live cell-based immunofluorescence assay with HEK293A cells transfected with full-length MOG (human MOG alpha-1 EGFP fusion protein), as previously described.3 

Investigators blinded to clinical data performed NfL analysis in all sera and, when available, in CSF samples. Sera/CSF of MOG-Ab-positive cases were obtained during the index attack, with the exception of two patients asymptomatic at sampling. Measurement of NfL concentration was analysed in duplicates using SIMOA Nf-light kit with SR-X immunoassay analyser (Quanterix, Boston, Massachusetts, USA) which runs ultrasensitive paramagnetic bead-based enzyme-linked immunosorbent assays.

### Statistical analysis

Continuous/categorical variables were reported as median (range) and percentages, respectively. Mann-Whitney U test and Wilcoxon signed-rank test were used for pairwise comparison of NfL levels within and between groups, as appropriate according …
Asynchronous magnetic bead rotation (AMBR) biosensor in microfluidic droplets for rapid bacterial growth and susceptibility measurements (2011)

Inappropriate antibiotic use is a major factor contributing to the emergence and spread of antimicrobial resistance. The long turnaround time (over 24 hours) required for clinical antimicrobial susceptibility testing (AST) often results in patients being prescribed empiric therapies, which may be inadequate, inappropriate, or overly broad-spectrum. A reduction in the AST time may enable more appropriate therapies to be prescribed earlier. Here we report on a new diagnostic asynchronous magnetic bead rotation (AMBR) biosensor droplet microfluidic platform that enables single cell and small cell population growth measurements for applications aimed at rapid AST. We demonstrate the ability to rapidly measure bacterial growth, susceptibility, and the minimum inhibitory concentration (MIC) of a small uropathogenic Escherichia coli population that was confined in microfluidic droplets and exposed to concentrations above and below the MIC of gentamicin. Growth was observed below the MIC, and no growth was observed above the MIC. A 52% change in the sensor signal (i.e. rotational period) was observed within 15 minutes, thus allowing AST measurements to be performed potentially within minutes.
Mineral-insulated metal-sheathed conductors (1946)

The paper records the progress made in the application of powdered mineral insulation to metal-sheathed conductors. It describes manufacturing methods and the application of those products which have reached a commercial stage of development. Mineral-insulated copper-covered (m.i.c.c.) cable is dealt with at greater length and it is thereby hoped that a solution to some cabling problems may be indicated.
Three-dimensional linear instability in pressure-driven two-layer channel flow of a Newtonian and a Herschel–Bulkley fluid (2010)

The three-dimensional linear stability characteristics of pressure-driven two-layer channel flow are considered, wherein a Newtonian fluid layer overlies a layer of a Herschel–Bulkley fluid. We focus on the parameter ranges for which Squire’s theorem for the two-layer Newtonian problem does not exist. The modified Orr–Sommerfeld and Squire equations in each layer are derived and solved using an efficient spectral collocation method. Our results demonstrate the presence of three-dimensional instabilities for situations where the square root of the viscosity ratio is larger than the thickness ratio of the two layers; these “interfacial” mode instabilities are also present when density stratification is destabilizing. These results may be of particular interest to researchers studying the transient growth and nonlinear stability of two-fluid non-Newtonian flows. We also show that the “shear” modes, which are present at sufficiently large Reynolds numbers, are most unstable to two-dimensional disturbances.
Efekat implicitne kauzalnosti kod dece i odraslih (2010)

Prvi cilj ovog rada je ispitati fenomen implicitne kauzalnosti kod dece i odraslih. Drugi cilj je ispitati značaj teorije uma, uzrasta i maternjeg jezika za javljanje efekta implicitne kauzalnosti. U ispitivanju je učestvovalo ukupno 212 ispitanika, od toga 128 ispitanika predškolskog uzrasta i 84 odrasla ispitanika srpskog i mađarskog maternjeg jezika. Lista stimulusa je obuhvatala glagole koji opisuju akciju i glagole koji opisuju stanje, ukupno18 glagola. Svi glagoli su se odnosili na interpersonalne relacije. Glagoli su prikazani u vidu proste interakcije: 'osoba A glagol osobu B'. Zadatak ispitanika je bio da pripišu kauzalnu odgovornost jednom od dva člana interakcije. Značaj teorije mišljenja, uzrasta i maternjeg jezika za javljanje efekta implicitne kauzalnosti ispitan je multivarijatnom analize varijanse za ponovljena merenja. Varijabla Uzrast (F(3,204)= 7.289; p< .01; Eta2= .097) ostvaruje statistički značajne efekte, dok je varijabla Maternji jezik u statistički značajnoj interakciji sa varijablom Uzrast (F(3,204)= 14.607; p< .001; Eta2= .087). Rezultati pokazuju da se trend odgovaranja odraslih ispitanika razlikuje od načina na koji ispitanici predškolskog uzrasta pripisuju kauzalnost jednom ili drugom članu interakcije, međutim kod dece su uočljivi različiti obrazci odgovaranja i s obzirom na prisustvo teorije uma. Ispitanici predškolskog uzrasta sa teorijom mišljenja pokazuju trend odgovaranja koji je sličan načinu pripisivanja kauzalnosti kod odraslih. Na osnovu nalaza može se zaključiti da razvoj sposobnosti razumevanja i tumačenja implicitnih informacija koje su deo verbalne komunikacije zahteva izvesne sposobnosti razumevanja mentalnih stanja. Tek kada razvije teoriju uma, dete je sposobno da odgovornost za doživljaje i postupke pripiše jednom ili drugom članu interakcije.
Domestic Everyday Life, Manners, and Customs in the Ancient World (1873)

History is, of all studies, the most interesting and the most generally followed. By this means we become acquainted with what has taken place during the ages of the world which preceded our own; and vast and valuable indeed are the lessons to be learned from the extended experience thus afforded. Of all the various branches of history, that which relates to the domestic everyday life of our fellow-creatures who have lived before us under very different circumstances from those by which we are surrounded, and who have been influenced by events and causes totally different from any of those by which we can be affected, appears to me to be by far the most useful for us to be acquainted with. An account of the wars which have been waged between different nations, a narrative of the political intrigues which have been carried on in certain states, a description of the various kings and queens who have reigned over particular peoples, possess their peculiar attractions for some tastes; but a relation of what were the modes of life, the daily pursuits, the ōrdinary occupations, and the common resources of the people themselves at these various periods of the world's history, appears to me to be a subject that comes home more nearly to us, and is calculated more warmly to excite our interest than any of the former matters. We shall thus be led to trace out the earliest dawn of civilisation, and shall have an opportunity of watching its course from the period when its light first gleamed above the horizon, to that when its midday splendour served to disperse the darkness of barbarism, and to diffuse knowledge and refinement wherever its rays had penetrated.
THE PRODUCTION OF CELLULASE BY FUNGI ON MIXED CELLULOSIC SUBSTRATES (1960)

Using jute, alkali-treated jute, holocellulose from jute, and filter paper as substrates, a total of 124 fungi were tested for production of cellulolytic enzyme capable of hydrolyzing powdered filter paper and swollen cellulose. Of these, only 15 organisms failed to produce the enzyme on any substrate, and 48 produced cellulase on filter paper, so that in most species cellulase production could be induced only by mixed cellulosic substrates. Among such species were many that are ordinarily regarded as non-cellulolytic, while on the other hand comparatively little enzyme could be detected with several well-known cellulose decomposers strongly degrading cellulose in vivo. Factors stimulating enzyme production on mixed cellulosic substrates were micronutrients and hemicellulose. For most species, excluding a few of the strong cellulose decomposers, a partial loosening of the hemicellulose seemed to favor enzyme production best. Some cellulase was produced on free hemicellulose alone, but not on starch and sugars, although in presence of cellulose these substances stimulated enzyme production by a few ordinarily weak species; on strong cellulose decomposers the effect of these additional carbon sources was opposite, possibly due to a sparing action on cellulose.
Hyperbilirubinemia and neonatal jaundice. (1995)

Jaundice is a common physiologic problem seen in both term and preterm infants. Normal transitional changes in bilirubin metabolism lead to physiological jaundice in many infants. In some infants these normal changes at birth may be exaggerated, such as occurs with immaturity, or may interact with health alterations (pathologic jaundice), resulting in the accumulation of excess bilirubin and development of hyperbilirubinemia. Caregivers must appreciate the processes and the basis for physiologic jaundice and hyperbilirubinemia and recognize infants at risk for these disorders. This article reviews neonatal bilirubin metabolism as a basis for understanding the causes and treatment of physiologic jaundice and hyperbilirubinemia arising from either physiologic or pathologic causes. Patterns of bilirubin in breast fed infants are discussed along with other issues related to breast feeding and jaundice. Treatment of hyperbilirubinemia and implications for nursing assessment and management of infants under phototherapy are also described.
Modulation of Transient Receptor Potential Vanilloid 4-Mediated Membrane Currents and Synaptic Transmission by Protein Kinase C (2009)

These results indicate that TRPV4 and TRPV1 are co-expressed in certain DRG neurons and TRPV4 can be sensitized by PKC not only in DRG neuronal cell bodies, but also in the central sensory and non-sensory nerve terminals. Co-expression of TRPV1 and TRPV4 ion channels, their modulation of synaptic transmission and their sensitization by PKC may synergistically play a role in nociception.
Color perimetry for assessment of primary open-angle glaucoma. (1990)

The authors report the development of a color perimetry procedure which compares sensitivity of the short-wavelength color-vision mechanism in the peripheral visual field for normal eyes, eyes with ocular hypertension, and eyes with primary open-angle glaucoma. To isolate the short-wavelength cone mechanism, they modified an automatic projection perimeter to blue-on-yellow color perimetry and used a monochromatic 440-nm stimulus and a broad-band bright yellow background. The three groups of subjects were matched for age and lens density. Refraction, pupil size, acuity, and medication were controlled. Under these conditions, most glaucomatous eyes showed reduced sensitivities more than two standard deviations below normal. Normal control eyes were significantly different from eyes with ocular hypertension only in the superior nasal field (P less than 0.05), but normal eyes differed from eyes with primary open-angle glaucoma in all areas of the field (P less than 0.01).
GMP‐140 (P‐selectin/CD62) binds to chronically stimulated but not resting CD4<sup>+</sup> T lymphocytes and regulates their production of proinflammatory cytokines (1992)

GMP-140 (P-selectin), a 140-kDa granular membrane glycoprotein localized to the alpha granules of platelets and the Weibel-Palade bodies of endothelial cells, is thought to play an important role in adhesive interactions predominantly between granulocytes, platelets and vascular endothelial cells during inflammation. Although GMP-140 binds to granulocytes, its binding to lymphocytes has not been demonstrated. Using genetically engineered IgG C gamma 1 fusion protein of the extracellular domains of GMP-140, we demonstrate that GMP-140 binds to chronically antigen (Ag)-stimulated CD4+ T cells. Freshly isolated CD4+ T cells did not bind GMP-140, but priming and subsequent stimulation with alloantigen induced and gradually increased expression of GMP-140-reactive structures on their surface. T cells isolated from rheumatoid synovial fluids also exhibited strong binding to GMP-140. The binding of GMP-140 to primed T cells is not influenced by preactivation with phorbol 12-myristate 13-acetate, is almost completely abolished by pretreatment of T cells with neuraminidase or trypsin, and is also strongly inhibited by EDTA, the soluble sulfated glycans dextran sulfate, fucoidan, and heparin, but not by chondroitin sulfates. In spite of its strong binding to Ag-primed T cells, GMP-140 did not modulate the proliferative responses of these cells to various stimuli. However, GMP-140 in conjunction with anti-T cell receptor alpha beta monoclonal antibodies augmented the production of granulocyte-macrophage colony-stimulating factor GM-CSF and inhibited the production of interleukin-8 by Ag-primed T cells without influencing their tumor necrosis factor-alpha production. These results suggest that GMP-140 binds to chronically stimulated CD4+ T cells and differentially modulates their production of proinflammatory cytokines. The ability of Ag-primed T cells to bind GMP-140 may facilitate interactions with activated platelets and endothelial cells affecting the course of inflammation.
Financial risk analysis of Cambodia Kamchay hydropower BOT project (2013)

Subject area Management science, operational and financial risk of overseas enterprises. Study level/applicability This case is mainly applicable to international business course and project management course. Case overview Since 1992, the Great Mekong sub-regional economic cooperation between China and ASEAN countries was officially launched and set free economic zone. Hydropower is starting to develop in recent years in Cambodia, and it is a good significance to Cambodia's industry. Furthermore, most of hydropower plants in Cambodia are built by Chinese companies. Thus, this paper will analyze the current risk and condition of Kamchay hydropower, as well as the development of Chinese enterprise for Cambodia economic and social development. Expected learning outcomes This case study provides students concepts on international business, project management, and operational risk of overseas enterprises. The principle of project contracting, labor cooperation, and project financial in international process are considered together with the implications they have for advancing understanding of the problem of the host country's government interests and the various risk of enterprises in international BOT projects. Supplementary materials Teaching notes are available for educators only. Please contact your library to gain login details or email support@emeraldinsight.com to request teaching notes.
Generalizing Inverse Perspective (2005)

Inverse perspective mapping schemes have been presented in the past as frameworks in which autonomous navigation could be performed on flat surfaces, using optical flow as the main percept. We propose a generalization of these models for uneven terrains. Given an inclinometer indicating the direction of gravity and some simple odometry parameters, the visual and positional information are combined to reconstruct the 3D elevation map of navigational surfaces within the visual field. Camera transformations are applied directly on the image plane. We provide noise and sensitivity analysis using random, zero-mean Gaussian noise to determine the robustness of the proposed model.
Design and Formulation of Tablets of a New Antineoplastic Drug: Amonafide (1995)

(1995). Design and Formulation of Tablets of a New Antineoplastic Drug: Amonafide. Drug Development and Industrial Pharmacy: Vol. 21, No. 2, pp. 185-197.
A Proposed Cross Platform Privacy and Security Framework for Supply Chain Information Sharing (2009)

Information sharing has become eminent to supply chain management, as it allows supply chain partners to collaborate more closely. However, currently supply chain partners are often on disjoint information platforms, which prevent them from effectively sharing critical supply chain information. One of the main barriers of information sharing is revealing confidential information to unintended parties and thus the disclosure of privacy. Therefore the information sharing needs and characteristics of a supply chain has been analyzed and subsequently a cross platform privacy and security framework to allow safe information sharing has been proposed.
Solar cell efficiency tables (version 35) (2010)

Abstract Consolidated tables showing an extensive listing of the highest independently confirmed efficiencies for solar cells and modules are presented. Guidelines for inclusion of results into these tables are outlined and new entries since July 2009 are reviewed. Copyright © 2010 John Wiley & Sons, Ltd.
Comparison and Analysis of Evaluation System of Child Care Program in Primary Health Care System in the East Azerbaijan Province Based on Comprehensive Evaluation Model (CIPP) (2014)

Background and objectives: Planning plays an important role in improving children's health and an evaluation system is necessary to planning. The purpose of this study was comparing and analyzing evaluation system of child care program in primary health care system in the Eastern Azerbaijan province based on Comprehensive Evaluation Model (CIPP). Material and Methods : This is a cross sectional study. The process includes a review of current evaluation system, comparison and analysis of the system based on a comprehensive model and to assess and identify the strengths and weaknesses of the current systems. The quantitative methods (such as brainstorming, observation and interview) and consensus of study group about the results of the study were used for analyzing and interpreting results. Results: It showed that not enough attention was paid to the context and performance and the content of evaluation just includes inputs and processes based on the finding. Specific criteria and impact were considered in four areas (context, input, process and outcome) and all levels which were according to the proposal and based on the CIPP model. Conclusion: Evaluation is a control process tool by higher levels and self-assessment by service provider is not considered in the current system. Evaluation includes quantitative aspects and not the quality of process. So, it is recommended that forecasting system that utilizes evaluation will result in improving future planning and a scientific model to be used in designing evaluation program. ​