gebhart/patrepeval huggingface dataset:
Band-gap-graded Cu2ZnSn(S1-x,Sex)4 Solar Cells Fabricated by an Ethanol-based, Particulate Precursor Ink Route (2013)

Solution processing of earth-abundant Cu2ZnSn(S1-x,Sex)4 (CZTSSe) absorber materials is an attractive research area in the economical and large-scale deployment of photovoltaics. Here, a band-gap-graded CZTSSe thin-film solar cell with 7.1% efficiency was developed using non-toxic solvent-based ink without the involvement of complex particle synthesis, highly toxic solvents, or organic additives. Despite the high series resistance due to the presence of a thick Mo(S,Se)x layer and Zn(S,Se) aggregates, a high short-circuit current density (JSC) was generated. In addition, there was no significant difference in open circuit voltages (VOC) between CZTS (0.517 V) and CZTSSe (0.505-0.479 V) cells, despite a significant band gap change from 1.51 eV to 1.24 eV. The high JSC and less loss of VOC are attributed to the effect of band gap grading induced by Se grading in the CZTSSe absorber layer. Our environmentally benign ink approach will enable the realization of low-cost, large-area, high-efficiency thin-film solar cells.
Paramagnetic Liposomes as Innovative Contrast Agents for Magnetic Resonance (MR) Molecular Imaging Applications (2008)

This article illustrates some innovative applications of liposomes loaded with paramagnetic lanthanide-based complexes in MR molecular imaging field. When a relatively high amount of a Gd(III) chelate is encapsulated in the vesicle, the nanosystem can simultaneously affect both the longitudinal (R(1)) and the transverse (R(2)) relaxation rate of the bulk H2O H-atoms, and this finding can be exploited to design improved thermosensitive liposomes whose MRI response is not longer dependent on the concentration of the probe. The observation that the liposome compartmentalization of a paramagnetic Ln(III) complex induce a significant R(2) enhancement, primarily caused by magnetic susceptibility effects, prompted us to test the potential of such agents in cell-targeting MR experiments. The results obtained indicated that these nanoprobes may have a great potential for the MR visualization of cellular targets (like the glutamine membrane transporters) overexpressing in tumor cells. Liposomes loaded with paramagnetic complexes acting as NMR shift reagents have been recently proposed as highly sensitive CEST MRI agents. The main peculiarity of CEST probes is to allow the MR visualization of different agents present in the same region of interest, and this article provides an illustrative example of the in vivo potential of liposome-based CEST agents.
T Cell Memory (2002)

Typical immune responses lead to prominent clonal expansion of antigen-specific T and B cells followed by differentiation into effector cells. Most effector cells die at the end of the immune response but some of these cells survive and form long-lived memory cells. The factors controlling the formation and survival of memory T cells are reviewed.
A semantic image annotation model to enable integrative translational research. (2009)

Integrating and relating images with clinical and molecular data is a crucial activity in translational research, but challenging because the information in images is not explicit in standard computer-accessible formats. We have developed an ontology-based representation of the semantic contents of radiology images called AIM (Annotation and Image Markup). AIM specifies the quantitative and qualitative content that researchers extract from images. The AIM ontology enables semantic image annotation and markup, specifying the entities and relations necessary to describe images. AIM annotations, represented as instances in the ontology, enable key use cases for images in translational research such as disease status assessment, query, and inter-observer variation analysis. AIM will enable ontology-based query and mining of images, and integration of images with data in other ontology-annotated bioinformatics databases. Our ultimate goal is to enable researchers to link images with related scientific data so they can learn the biological and physiological significance of the image content.
From simulink to SCADE/lustre to TTA (2003)

We present a layered end-to-end approach for the design and implementation of embedded software on a distributed platform. The approach comprises a high-level modeling and simulation layer (Simulink), a middle-level programming and validation layer (SCADE/Lustre) and a low-level execution layer (TTA). We provide algorithms and tools to pass from one layer to the next. First, a translator from Simulink to Lustre. Second, a set of real-time and code-distribution extensions to Lustre. Third, implementation techniques for decomposing a Lustre program into tasks and messages, scheduling the tasks and messages on the processors and the bus, distributing the Lustre code on the execution platform, and generating the necessary "glue" code.
WNK1 kinase isoform switch regulates renal potassium excretion (2006)

Members of the WNK family of serine/threonine kinases have been implicated as important modulators of salt homeostasis, regulating the balance between renal sodium reabsorption and potassium excretion. Gain-of-expression mutations in the WNK1 gene uncouple Na(+) and K(+) balance and cause a familial disorder of diminished renal potassium excretion, excessive sodium retention, and hypertension (pseudohypoaldosteronism type II or Gordon's syndrome). Alternative splicing of the WNK1 gene produces a kidney-specific short form of WNK1 (KS-WNK1) and a more ubiquitous long form (L-WNK1), but it is not clear how either of these isoforms influence renal potassium excretion. Here we demonstrate that KS-WNK1 and L-WNK1 converge in a pathway to regulate the renal outer-medullary K(+) channel, Kir1.1. Reconstitution studies in Xenopus oocytes reveal that L-WNK1 significantly inhibits Kir1.1 by reducing cell surface localization of the channel. A catalytically inactive L-WNK1 mutant has no inhibitory effect on Kir1.1, indicating that channel inhibition depends on kinase activity. KS-WNK1, lacking an intact kinase domain, does not directly alter Kir1.1. Instead, KS-WNK1 negatively regulates L-WNK1 to release Kir1.1 from inhibition. Acute dietary potassium loading increases the relative abundance of KS-WNK1 to L-WNK1 transcript and protein in the kidney, indicating that physiologic up-regulation of Kir1.1 activity involves a WNK1 isoform switch and KS-WNK1-mediated release from L-WNK1 inhibition. Thus, these observations provide evidence for the physiological regulation of Na(+) and K(+) balance by a kinase isoform switch mechanism.
Performance of a prototype amorphous silicon active pixel sensor array using a-Se for direct x-ray conversion (2010)

Active pixel sensor (APS) circuits are an alternate to passive pixel sensor (PPS) technology which, when integrated with a direct detection amorphous selenium (a-Se) photoconductor, can enable high performance, digital x-ray imaging applications such as real-time fluoroscopy due to their better signal-to-noise ratios at low dose. This paper presents experimental imaging results from a prototype 64×64 APS pixel array fabricated in a-Si technology. The prototype APS array is coated with a one millimeter thick layer of a-Se and the experimental results are evaluated using a standard radiography x-ray beam quality RQA5. The APS experimental results are compared with a standard real-time detector (FPD14) imaging array under the same x-ray beam conditions. In addition, we will theoretically examine the best achievable performance for our APS array fabricated in state-of-the-art a-Si technology and compare the results to state-of-the-art PPS panels for real-time fluoroscopy.
Measurement by isotope dilution mass spectrometry of equiline and oestrone in serum of women taking tablets of equine oestrogens (1983)

The technique of isotope dilution mass spectrometry was used for the measurement of equiline and oestrone as well as the sulphate esters of the two phenolic steroids in serum. Serum samples were obtained from an ovariectomized woman who received a tablet of 1.25 mg of various conjugated equine oestrogens. For the measurement of the non-conjugated oestrogens 20 pg (2,4,16,16-2H4)equiline and 100 pg (6,7-3H2)oestrone were added to serum samples of 0.5–4.0 ml. The steroids were extracted with 15 ml ether and separated from each other by column chromatography on Sephadex LH-20. This was followed by derivative formation with heptafluorobutyric anhydride. The ester derivatives of the two steroids were injected into a SE-52 capillary column which was coupled to a mass spectrometer. For the recording of equiline and the corresponding isotopically labelled equiline the instrument was adjusted to m/z 464 and 468, respectively. For the measurement of oestrone and (6,7-3H2)oestrone the m/z values 466 and 470 were monitored continuously. The amounts of equiline and oestrone in the serum samples were calculated from the isotope ratios measured by selected ion monitoring. For the determination of the sulphate esters of the oestrogenic steroids the serum samples (0.5–4.0 ml) from which the non-conjugated steroids had been removed by ether extraction were treated with 15 ml methanol. The serum proteins were sedimented by centrifugation and the methanolic supernatant was evaporated to dryness. The sulphate esters of the phenolic steroids were then hydrolysed by enzymatic cleavage. After an incubation period of 48 h, 50 pg (2,4,16,16-2H4)equiline and 150 pg (6,7-3H2)oestrone were added to the mixture. The oestrogens were then extracted with cyclohexane and determined as described for the measurement of the nonconjugated phenolic steroids. The precision of the method for the measurement of equiline in the range from 1.5–50 pg was at 7.3% (CV) and for oestrone in the range from 30–150 pg at 3.6% (CV). The accuracy of the procedure was achieved by the use of the isotope dilution principle in combination with the highly specific technique of selected ion monitoring.
Embedding AC Power Flow in the Complex Plane Part I: Modelling and Mathematical Foundation (2016)

Part I of this paper embeds the AC power flow problem with voltage control and exponential load model in the complex plane. Modeling the action of network controllers that regulate the magnitude of voltage phasors is a challenging task in the complex plane as it has to preserve the framework of holomorphicity for obtention of these complex variables with fixed magnitude. The paper presents two distinct approaches to modelling the voltage control of generator nodes. Exponential (or voltage-dependent) load models are crucial for accurate power flow studies under stressed conditions. This new framework for power flow studies exploits the theory of analytic continuation, especially the monodromy theorem for resolving issues that have plagued conventional numerical methods for decades. Here the focus is on the indispensable role of Pade approximants for analytic continuation of complex functions, expressed as power series, beyond the boundary of convergence of the series. The zero-pole distribution of these rational approximants serves as a proximity index to voltage collapse. Finally the mathematical underpinnings of this framework, namely the Stahl's theory and the rate of convergence of Pade approximants are explained.
Design of a New 45 kWe High-Flux Solar Simulator for High-Temperature Solar Thermal and Thermochemical Research (2011)

In this paper, we present a systematic procedure to design a solar simulator for high-temperature concentrated solar thermal and thermochemical research. The 45 kWe simulator consists of seven identical radiation units of common focus, each comprised of a 6.5 kWe xenon arc lamp close-coupled to a precision reflector in the shape of a truncated ellipsoid. The size and shape of each reflector is optimized by a Monte Carlo ray tracing analysis to achieve multiple design objectives, including high transfer efficiency of radiation from the lamps to the common focal plane and desired flux distribution. Based on the numerical results, the final optimized design will deliver 7.5 kW over a 6 cm diameter circular disk located in the focal plane, with a peak flux approaching 3.7 MW/m2.
BEETHOVEN AND KANT (1961)

Journal Article BEETHOVEN AND KANT Get access ROBERT L. JACOBS ROBERT L. JACOBS Search for other works by this author on: Oxford Academic Google Scholar Music and Letters, Volume 42, Issue 3, July 1961, Pages 242–251, https://doi.org/10.1093/ml/42.3.242 Published: 01 July 1961
Phloem‐specific expression of a plant homeobox gene during secondary phases of vascular development (1996)

This paper reports the isolation and characterization of a homeobox gene (VAHOX1) from Lycopersicon esculentum encoding a homeodomain protein that contains a leucine zipper motif. The bipartite homeodomain-leucine zipper (HD-Zip) motif has only been found in homeobox genes from dicotyledonous plants, indicating that this type of transcription factor regulates particular developmental processes in these plant species. Here, the genomic organization, sequence comparison and expression analysis of VAHOX1 are described. Transcriptional fusion of the 5' promoter region of VAHOX1 with the reporter GUS gene (VAHOX1-GUS) and expression analysis of this construct in transgenic plants indicates that VAHOX1 is specifically expressed in the phloem during phases of secondary growth. Unlike other plant homeobox genes, VAHOX1 does not appear to be expressed in meristems, and the function of VAHOX1 is considered a likely candidate molecule that may participate in the regulation of the identity and/or activity of phloem tissues during secondary phases of vascular development.
Tautomerism of a Nitro Derivative of <i>N</i>-Salicylideneaniline in Crystals (1999)

Abstract X-Ray crystallographic and electronic absorption spectroscopic studies on N-(2-hydroxy-3-nitrobenzylidene)aniline revealed that this compound exists as a mixture of the OH and NH forms with nearly the equal populations in crystals.
Piccolo, a Ca2+ Sensor in Pancreatic β-Cells (2002)

We have previously shown that cAMP-binding protein cAMP-guanidine nucleotide exchange factor II (GEFII) (or Epac2) interacting with Rim2 is involved in cAMP-dependent, protein kinase A-independent exocytosis in pancreatic beta-cells. The action of the cAMP-GEFII.Rim2 complex requires both intracellular cAMP and Ca(2+). Although Rim2 has C(2) domains, its role as a Ca(2+) sensor has remained unclear. In the present investigation, we have discovered that Piccolo, a CAZ (cytoskeletal matrix associated with the active zone) protein in neurons that is structurally related to Rim2, also binds to cAMP-GEFII and that it forms both homodimer and heterodimer with Rim2 in a Ca(2+)-dependent manner, whereas Rim2 alone does not form the homodimer. The association of Piccolo.Rim2 heterodimerization is stronger than Piccolo. Piccolo homodimerization. Treatment of pancreatic islets with antisense oligodeoxynucleotides against Piccolo inhibits insulin secretion induced by cAMP analog 8-bromo-cyclic AMP plus high glucose stimulation. These results suggest that Piccolo serves as a Ca(2+) sensor in exocytosis in pancreatic beta-cells and that the formation of a cAMP-GEFII.Rim2. Piccolo complex is important in cAMP-induced insulin secretion. In addition, this study suggests that CAZ proteins similar to those in neurons are also function in pancreatic beta-cells.
Social mobile Augmented Reality for retail (2009)

Consumers are increasingly relying on Web-based social content, such as product reviews, prior to making to a purchase. Recent surveys in the retail industry confirm that social content is indeed the #1 aid in a buying decision. Currently, accessing or adding to this valuable Web-based social content repository is mostly limited to computers far removed from the site of the shopping experience itself. We present a mobile augmented reality application, which extends such social content from the computer monitor into the physical world through mobile phones, providing consumers with in situ information on products right when and where they need to make buying decisions.
Small Molecule Signals that Direct the Route of a Molecular Cargo (2012)

The route taken by a DNA cargo on a branched track can be controlled by the small molecule adenosine using a pair of aptamers that reciprocally block and unblock branches of the track in response to adenosine binding.
G Protein-Coupled Receptor Kinases (2005)

As the largest family of membrane receptors, G protein-coupled receptors (GPCRs) transduce a large number of extracellular signals from hormones, neurotransmitters, chemokines, and other environmental stimuli to the interior of cells and play fundamental roles in the regulation of cellular functions. One of the most important features of GPCR-mediated signal transduction is that the activation of the receptor also triggers a feedback regulatory mechanism to attenuate GPCR-mediated signal transduction (homologous desensitization) in the cell. Homologous receptor desensitization is a common mechanism employed by the cell to prevent potential harmful effects that result from persistent activation of the signaling pathways. The initial event of GPCR desensitization occurs within seconds to minutes after agonist binding and is induced by receptor phosphorylation that is catalyzed by GPCR kinases (GRKs) ().
ChemInform Abstract: REACTION OF TETRAETHYL CARBOMETHOXYMETHYLENE‐1,1‐DIPHOSPHONITE WITH ALKYL HALIDES (1978)

Abstract Das Diphosphonit (I) reagiert mit Chlormethylether (IIa) oder Iodmethan (IIb) zu den Verbindungen (IIIa) und (IIIb) mit 2 PV‐Atomen.
Filamin A mediates interactions between cytoskeletal proteins that control cell adhesion (2010)

Cell adhesion, spreading and migration on extracellular matrices are regulated by complex processes that involve the cytoskeleton and a large array of adhesion receptors, including the β1 integrin. Filamin A is a large, multi-domain, homodimeric actin binding protein that contributes to the mechanical stability of cells and interacts with several proteins that regulate cell adhesion including β1 integrin and several protein kinases. Here we review current data on the structure, mechanical properties and intracellular signaling functions of filamin that regulate cell adhesion. We also consider new data showing that interactions of filamin A with intermediate filaments and protein kinase C enable tight regulation of β1 integrin function and consequently early events in cell adhesion and migration on extracellular matrix proteins.
The Synthesis of D-Mannoheptulose, and the Preparation of Some of its Derivatives (1939)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of D-Mannoheptulose, and the Preparation of Some of its DerivativesEdna M. Montgomery and C. S. HudsonCite this: J. Am. Chem. Soc. 1939, 61, 7, 1654–1658Publication Date (Print):July 6, 1939Publication History Published online1 May 2002Published inissue 6 July 1939https://pubs.acs.org/doi/10.1021/ja01876a007https://doi.org/10.1021/ja01876a007research-articleACS PublicationsRequest reuse permissionsArticle Views151Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Codierung von farbigen Bewegtbildszenen mit 64 kbit/s – Ein neuer Ansatz zur Verwirklichung eines Bildtelefons im ISDN (Teil III) (1989)

Article Codierung von farbigen Bewegtbildszenen mit 64 kbit/s – Ein neuer Ansatz zur Verwirklichung eines Bildtelefons im ISDN (Teil III) was published on May 1, 1989 in the journal Frequenz (volume 43, issue 5).
Long-term disease-free survival in immature teratoma of the ovary (1982)

Long-term follow-up on five patients with immature teratoma of the ovary with residual metastatic Grade 0 disease following chemotherapy is reported. All five patients are free of progressive disease 40–96 months following original diagnosis. The concept of ‘retroconversion’ following chemotherapy for immature teratoma of the ovary is reemphasized. Cancer 50:159–162, 1982.
Preparation and structure of the 1:2 π-molecular complex of phenothiazine with pyromellitic dianhydride (1985)

Single crystals of the black 1:2 donor–acceptor complex of phenothiazine with pyromellitic dianhydride, PTZ:(PMDA)2, were grown by plate sublimation at ∼163 °C from the zone-refined components. The l:1 complex is produced at lower temperatures. Crystals of the 1:2 complex are monoclinic, P21/c, Z=4, a=7.689(3), b=12.953(5), c=28.14(2) Å, β=104.30(2)° at T=19 °C. The structure was refined from 2863 x-ray diffraction reflection intensities for which I&gt;2.0σ(I) to R=0.064 and Rw=0.057. The structure consists of continuous ... DADA ... polar stacks as does the l:1 complex, but the stacks, which are parallel to the a axis, are separated in the c direction by the extra PMDA molecule. The overlap of adjacent molecules in the stack in the 1:2 complex is more closely related to the overlap of adjacent molecules in the π-molecular complex of PMDA with anthracene. The resultant angle between the stack axis and the normal to the planar molecules is 27.1°. The geometry of the individual molecules in the l:2 complex is not significantly different from those in the l:1 complex.
Biodosimetry of Chernobyl cleanup workers from Estonia and Latvia using the glycophorin A in vivo somatic cell mutation assay. (1997)

The reactor accident at Chernobyl in 1986 necessitated a massive environmental cleanup that involved over 600,000 workers from all 15 Republics of the former Soviet Union. To determine whether the whole-body radiation received by workers in the course of these decontamination activities resulted in a detectable biological response, over 1,500 blood samples were obtained from cleanup workers sent from two Baltic countries, Estonia and Latvia. Here we report the results of studies of biodosimetry using the glycophorin A (GPA) locus in vivo somatic cell mutation assay applied to 734 blood samples from these workers, to 51 control samples from unexposed Baltic populations and to 94 samples from historical U.S. controls. The data reveal inconsistent evidence that the protracted radiation exposures received by these workers resulted in a significant dose-associated increase in GPA locus mutations compared with the controls. Taken together, these data suggest that the average radiation exposure to these workers does not greatly exceed 10 cGy, the minimum levels at which radiation effects might be detectable by the assay. Although the protracted nature of the exposure may have reduced the efficiency of induction of GPA locus mutations, it is likely that the estimated physical doses for these cleanup worker populations (median reported dose 9.5 cGy) were too low to result in radiation damage to erythroid stem cells that can be detected reliably by this method.