gebhart/patrepeval huggingface dataset:
Latency Reduction for Mobile Backhaul by Pipelining LTE and DOCSIS (2017)

The small cell market has been growing. To backhaul wireless traffic from small cells, the mobile network operators (MNOs) are looking into economically viable solutions, specifically the hybrid fiber coaxial networks (HFC), in addition to the traditional choice of fiber. When the latencies from both the wireless and the HFC networks are added together, it can result in noticeable end-to-end system latency, particularly under network congestion. If the two networks could somehow coordinate with each other, it would be possible to decrease the total system latency and increase system performance. In this paper, we propose a method to improve upstream user-to-mobile core latency by coordinating the LTE and HFC scheduling. The method reduces the impact on system latency from the HFC network's request-grant-data loop, which is the main contributor of backhaul upstream latency. Through simulation, we show that coordinated scheduling improves overall system latency.
Liquid crystal spatial light modulator with a transmissive amorphous silicon photoconductor (1988)

A spatial light modulator with a thin (1-microm) amorphous silicon (PIN) photoconductor has been demonstrated with a threshold sensitivity of <3 microw/cm(2). A novel compound electrode design greatly increases the efficiency allowing the use of a photoconductive layer thin enough to achieve good transmission. The performance characteristics are reported and compared to the predictions of a theoretical model of the device.
Les phonothèques comme outil de transmission du savoir en sciences de l’homme : l’exemple de la Maison méditerranéenne des sciences humaines et sociales (2007)

Casse Corinne, Ginouvès Véronique. Les phonothèques comme outil de transmission du savoir en sciences de l’homme : l’exemple de la Maison méditerranéenne des sciences humaines et sociales. In: Transmission et diffusion des savoirs dans le Sud de la France. Actes du 126e Congrès national des sociétés historiques et scientifiques, « Terres et hommes du Sud », Toulouse, 2001. Paris : Editions du CTHS, 2007. pp. 130-137. (Actes des congrès nationaux des sociétés historiques et scientifiques, 126-13)
Zero ripple single stage AC-DC LED driver with unity power factor (2013)

The single stage LED Driver can achieve relatively high efficiency, however the low frequency ripple current is too significant if high power factor has been achieved. With two stages AC-DC LED Driver structure, we can achieve high power factor and tight current regulation at the same time. However, the drawback of the two stage structure is relatively low efficiency and high component cost. In this paper, an innovative single stage LED Driver with ripple cancellation technology has been proposed. We can achieve almost as high efficiency and low component cost as single stage LED Driver while maintaining comparable performance to the two stages LED Driver. Our experimental prototype can achieve 1.5mA Pk-Pk 120Hz ripple current, 0.99 power factor and 85.5% efficiency for a universal AC input, 35W (50V-0.7A) output application.
Normal blood pressure in patients with insulinoma despite hyperinsulinemia and insulin resistance. (1992)

This article examines the relationship between blood pressure and serum insulin patients with endogenous hyperinsulinemia due to insulinomas. The hypothesis that hyperinsulinemia is an independent causal factor in the development of essential hypertension in this patient population was investigated. Inappropriately high plasma concentrations of insulin and proinsulin were found in these patients; however, their blood pressure levels did not differ from those of normal control subjects. Moreover, the surgical removal of the insulinomas did not reduce their blood pressure. Therefore, these findings argue against the hypothesis that hyperinsulinemia is an independent causal factor in the development of essential hypertension in humans.
Photocapacitive MIS infrared detectors (1978)

A new class of room-temperature infrared detectors, which exploits the photocapacitive effect in MIS and MISIM devices, is reported. An (unoptimized) peak detectivity of ∼3×1012 W−1 cm Hz1/2 has been measured in a prototype Si device.
Near-Infrared Photoluminescent Ag<sub>2</sub>S Quantum Dots from a Single Source Precursor (2010)

Monodisperse Ag(2)S quantum dots (QDs) were synthesized via pyrolysis of Ag(DDTC) in oleic acid, octadecylamine, and 1-octadecene. The uniform alkyl-capped Ag(2)S QDs with a size of 10.2 nm emit near-IR emission at 1058 nm under 785 nm excitation.
Protective Antibody and CD8+ T-Cell Responses to the Plasmodium falciparum Circumsporozoite Protein Induced by a Nanoparticle Vaccine (2012)

The SAPN construct induces long-lasting antibody and cellular immune responses to epitope specific sequences of the P. falciparum circumsporozoite protein (PfCSP) and prevents infection in mice by a transgenic P. berghei parasite displaying the full length PfCSP.
Rapid preparation of blood and tissue samples for polymerase chain reaction. (1991)

We report a rapid and novel method for the preparation of DNA prior to amplification by polymerase chain reaction using a nonspecific thermophilic protease isolated from Thermus rt41A
Field device integration (2002)

Today, the large number of different device types and suppliers within a control system project makes the configuration task difficult and time-consuming. Different tools must be mastered and data must be exchanged between these tools. In the end the consistency of data, documentation and configurations can only be guaranteed by an intensive system test requiring detailed specialist knowledge. A solution can be achieved by standardizing suitable interfaces. For the computable description of device parameters the so called electronic device description language (EDDL) is specified. The electronic device description is used for the configuration and the operational behavior of a device. Furthermore, the field device tool (FDT) concept defines the interfaces between device-specific software components (device type manager-DTM) provided by the device supplier and the engineering tool of the control system manufacturer. A DTM can easily be developed using existing EDD files as shown in this article. So EDD and FDT are not contradictory technologies, but complement each other.
Ovarian response to recombinant human follicle-stimulating hormone: a randomized, antimüllerian hormone–stratified, dose–response trial in women undergoing in vitro fertilization/intracytoplasmic sperm injection (2014)

NCT01426386.
Interleukin‐2 diphtheria fusion protein (dab<sub>486</sub>il‐2) in refractory rheumatoid arthritis a double‐blind, placebo‐controlled trial with open‐label extension (1995)

Clinical responses were noted in patients treated with DAB486IL-2 (18%) compared with placebo (0%) in the double-blind phase. In the open-label phase, 33% of patients completing 3 monthly DAB486IL-2 cycles had improvement in arthritis activity. Further studies of IL-2 diphtheria fusion proteins are warranted to elucidate factors that may predict clinical response and define mechanism(s) of action.
Signal processing for automotive radar (2005)

With rising accident rates, researchers are looking for solutions to reduce fatalities. Some enhance car designs to protect drivers more adequately. Some propose improvements to the traffic and road systems to reduce the chances of accidents. Still others propose the installation of special gadgets to improve the situational awareness of drivers and to alert them to dangerous circumstances. A motor vehicle may be equipped with a radar sensor that checks the spatial environment around the vehicle. The radar is the most commonly adopted sensor for this purpose due to its all-weather capability. In this paper, a 77-GHz FMCW automotive radar signal processor is developed and implemented using the Renesas (previously Hitachi) SH7615 solutions engine development board. The project includes building additional required hardware, the DSP algorithm and a data simulator program to generate test data for testing. The main purpose of the automotive radar signal processor is to detect legitimate targets from unwanted clutter (e.g. road surfaces), and to extract target information from the radar returns. In this paper, the application of the new AND-OR CFAR is also introduced. The simple mathematical fusion models of the AND-OR CFAR are provided and explained here as well. This manuscript is divided into sections. The first section will delve into the basics and the building blocks of the automotive radar. The signal processing portion of this work will be presented in the second section. The data simulator built to simulate testing data is explained in the third section. Results from testing are put forward in section four. Conclusions drawn from the experience are presented in the last section.
The Ras Inhibitor S-<i>Trans, Trans</i>-Farnesylthiosalicylic Acid Exerts Long-Lasting Neuroprotection in a Mouse Closed Head Injury Model (2003)

Traumatic brain injury activates N-methyl-d-aspartate receptors (NMDAR) inducing activation of the Ras protein (a key regulator of cell growth, survival, and death) and its effectors. Thus, trauma-induced increase in active Ras-GTP might contribute to traumatic brain injury pathology. Based on this hypothesis, a new concept of neuroprotection is proposed, examined here by investigating the effect of the Ras inhibitor S-trans, trans-farnesylthiosalicylic acid (FTS) in a mouse model of closed head injury (CHI). Mice subjected to CHI were treated systemically 1 h later with FTS (5 mg/kg) or vehicle. After 1 h, Ras-GTP in the contused hemisphere showed a significant (3.8-fold) increase, which was strongly inhibited by FTS (82% inhibition) or by the NMDA-receptor antagonist MK-801 (53%). Both drugs also decreased active (phosphorylated) extracellular signal-regulated kinase. FTS prevented the CHI-induced reduction in NMDAR binding in cortical, striatal, and hippocampal regions, measured by [3H]-MK-801 autoradiography, and decreased lesion size by 50%. It also reduced CHI-induced neurologic deficits, indicated by the highly significant (P < 0.0001) 60% increase in extent of recovery. Thus, FTS provided long-term neuroprotection after CHI, rescuing NMDAR binding in the contused hemisphere and profoundly reducing neurologic deficits. These findings suggest that nontoxic Ras inhibitors such as FTS may qualify as neuroprotective drugs.
Recent Developments in Nonlinear Static Analysis of Structure (2009)

Performance-based seismic design(PSD),as a new method in 21th century,got its attention by engineers all over the word.The world recent developments of this PSD method were introduced.The shortcomings of nonlinear static analysis method in structural earthquake resistance evaluation,especially the effects of high-order mode to structure,were discussed and further research problems were pointed out.
CD4<sup>+</sup>T-cell subsets in rheumatoid arthritis (2012)

The exact pathogenesis of rheumatoid arthritis (RA) remains uncertain, however, autoimmune processes appear critical. In the past decades, several models implicated T cells at different levels; however, recent genetic advances have clearly indicated a role for T cells, maybe somehow limited to autoantibody positive disease. Processes involved in aging seem to occur early in RA and deviation from normal physiological pathways such as repertoire diversification, signaling, differentiation, polarisation or regulation also characterized T cells from RA patients. Despite such evidence, T-cell targeted therapies did not appear to be particularly successful with the exception of costimulation blockade, the reasons for this failure remaining unclear. Importantly, T-cell subsets demonstrated interesting biomarker features that remain to be investigated in relation with early diagnostic, prognostic and prediction of treatment response.
Reviving the past (2001)

The use of immersive virtual reality (VR) systems in museums is a recent trend, as the development of new interactive technologies has inevitably impacted the more traditional sciences and arts. This is more evident in the case of novel interactive technologies that fascinate the broad public, as has always been the case with virtual reality. The increasing development of VR technologies has matured enough to expand research from the military and scientific visualization realm into more multidisciplinary areas, such as education, art and entertainment. This paper analyzes the interactive virtual environments developed at an institution of informal education and discusses the issues involved in developing immersive interactive virtual archaeology projects for the broad public.
Racial Differences in the Association between Optic Disc Topography and Early Glaucoma (2003)

Structural characteristics of the optic disc that are best associated with early glaucoma included cup shape and rim area in both groups, but with a less pronounced association in African Americans. In addition, several other race-specific parameters that were independently associated with early glaucoma differed significantly between African Americans and whites. These race-specific differences were independent from the effect of optic disc area.
Efficacy of Tocilizumab in Patients Hospitalized with Covid-19 (2020)

Tocilizumab was not effective for preventing intubation or death in moderately ill hospitalized patients with Covid-19. Some benefit or harm cannot be ruled out, however, because the confidence intervals for efficacy comparisons were wide. (Funded by Genentech; ClinicalTrials.gov number, NCT04356937.).
Methanol Usage in Toluene Methylation with Medium and Large Pore Zeolites (2013)

The reaction of toluene methylation was investigated with four acidic zeolites of different pore geometries: the medium pore zeolites H-ZSM5 and H-ZSM11 as well as the large pore zeolites H-MOR and H-BEA. The methylation, methanol consumption, light hydrocarbon formation, and disproportionation rates for the reaction of toluene, p-xylene, and 1,2,4-trimethylbenezene with methanol were determined. The products of toluene methylation (e.g., xylenes and trimethylbenzenes) were readily methylated further in both medium and large pore zeolites. A considerably higher fraction of methanol was used to form light hydrocarbons with the medium pore zeolites than with large pore zeolites. This was related to the fact that the dealkylation of light hydrocarbons from highly methylated aromatics became more favorable relative to methylation at an earlier stage, that is, after fewer methyl groups were added to the aromatic ring. Increasing the effective residence time of bulky aromatic molecules with medium pore zeolites, modified either by coating the surface with tetraethyl orthosilicate or by increasing the intracrystal pore length, converted a larger fraction of methanol to light hydrocarbons via methylation and subsequent dealkylation of light hydrocarbons.
The HEFTI Model of Text to Hypertext Conversion (1991)

Manual authoring is a major bottleneck in the more widespread use of hypertext. The authoring process has been shown to be slow and labour intensive and hence expensive. Yet there already exists a large body of printed material which can be adopted for hypertext and hypermedia. In the project HEFTI (Hypertext Extraction From Text Incrementally), we are exploring methods of converting printed text into hypertext. We have developed a model which breaks the conversion process into a sequence of six modular components. The output of the conversion process are hypertext documents in a general specification language. In this paper we detail the model and our implementation of the HEFTI model. We believe the system demonstrates the validity of the model as it was used to convert a medium-sized technical textbook into hypertext within a (long) working day. We furthermore discuss two usability experiments that we carried out on HEFTI produced documents. In the conclusion of this paper we look at some open research issues.
Thermal Enhancement of Ultraviolet Mutability in a <i>tif-1 uvrA</i> Derivative of <i>Escherichia coli</i> B/r: Evidence That Ultraviolet Mutagenesis Depends upon an Inducible Function (1974)

Inhibition of DNA replication in E. coli results in coordinate expression of a cluster of diverse functions, including prophage induction and filamentous growth, many of which are thermally inducible, without inhibition of DNA synthesis, in strains carrying a mutation in the "tif" locus. It has been proposed that one of the inducible functions in this cluster is responsible for the ultraviolet mutability of E. coli. As a test of this hypothesis, the effect of postirradiation temperature elevation on ultraviolet mutability was compared in strains differing by a tif mutation. In a tif(+) strain, raising the temperature to 42 degrees after irradiation did not change the frequency of induced mutations to tryptophan-independence. Similar treatment of a tif-1 strain resulted in as much as a 10-fold increase in the induced mutation yield. Thermal enhancement of ultraviolet mutability in the tif-1 strain was prevented or promoted by agents known to exert parallel effects on thermal induction of lambda prophage in tif lysogens. The results support the hypothesis that ultraviolet mutability in E. coli depends upon an inducible function that is normally expressed only when DNA replication is inhibited.
Distributed authoring on the Web with the BSCW shared workspace system (1997)

S.9-16
Diarrhea and dengue control in rural primary schools in Colombia: study protocol for a randomized controlled trial (2012)

Current Controlled Trials ISRCTN40195031.
Submandibular gland and caries susceptibility in the obese Zucker rat (2010)

Obesity promotes proinflammatory changes within the submandibular gland, without affecting glandular architecture, in association with rampant caries; Cr(Pic)3 treatment provided some protective effects.
Quantification of a potent 5-HT<sub>2a</sub> antagonist and an active metabolite in rat plasma and brain microdialysate by liquid chromatography-tandem mass spectrometry (1997)

A method based on liquid chromatography-tandem mass spectrometry and microbore column separation was developed for the quantification of a potent 5-HT2a receptor antagonist (R)-(+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)etnyl]-4-piperidine-methanol (I) and the desmethyl metabolite (II) in rat brain extracellular fluid (ECF) following microdialysis sampling. The analytical method was also applied to determining plasma concentrations of these compounds. The lower limit of quantification (LLQ) for each compound in microdialysis perfusate is 500 pg/mL, which translates to <7 fmol (injected). The recovery of I and II for the microdialysis probe in brain ECF was 18.5 and 22.7%, respectively. The LLQ for each compound in plasma is 1 ng/mL. The inherent selectivity offered by tandem mass spectrometry eliminated chemical noise, thereby improving the detectability of these compounds. These methods were used to confirm that I and II penetrated the blood-brain barrier following administration of I to rats and enabled comparison of plasma and brain ECF concentrations.
Characterization of the hemA-prs region of the Escherichia coli and Salmonella typhimurium chromosomes: identification of two open reading frames and implications for prs expression (1993)

The prs gene, encoding phosphoribosylpyrophosphate synthetase, is preceded by a leader, which is 302 bp long in Escherichia coli and 417 bp in Salmonella typhimurium. A potential open reading frame (ORF) extends across the prs promoter and into the leader. The region between the prs coding region and an upstream gene (hemA) in E. coli and S. typhimurium was cloned, sequenced and shown to encode two ORFs of unknown function. ORF 1 encodes a 23 kDa protein and ORF 2 a 31 kDa protein, as observed by denaturing PAGE of extracts of cells bearing plasmids encoding the ORFs. Both ORFs are transcribed in the same direction as the prs gene with ORF 2 extending into the prs leader. Northern blot analysis showed that the prs message in E. coli was on 1.3 and 2.7 kb transcripts. The shorter transcript encoded the prs gene only, while the longer transcript also encoded the two ORFs. Thus, the prs gene is transcribed from two promoters, the first promoter (P1) originating upstream of ORF 1, and expressing the prs gene in a tricistronic operon and a second promoter (P2), located within the ORF 2 coding frame, which transcribes the prs gene only. The transcripts encoding prs only were 20 times as abundant as the tricistronic transcripts under all conditions examined. This was the case whether cells containing plasmid-encoded or only chromosomally encoded copies of the hemA-prs region were probed for these transcripts. Derepression of the prs gene upon pyrimidine starvation was shown to be due to an increase in the amount of message originating from the promoter P2.
Catalysis of Disulfide Isomerization in Thrombospondin 1 by Protein Disulfide Isomerase (1996)

Thrombospondin 1 is a multidomain glycoprotein from platelets and most cells that participates in diverse biological processes. The structure and some functional properties of thrombospondin 1 are regulated by disulfide interchange in the Ca(2+)-binding repeats and C-globular domain. The recent identification of the enzyme, protein disulfide isomerase, on the platelet surface suggested that protein disulfide isomerase may catalyze disulfide isomerization in platelet thrombospondin 1. Protein disulfide isomerase was found to form disulfide-linked complexes with thrombospondin 1, which is consistent with protein disulfide isomerase-mediated rearrangement of disulfide bonds in thrombospondin 1. To quantitate disulfide interchange in thrombospondin 1, perturbation of the enzyme inhibitory properties of platelet thrombospondin 1 were measured, specifically changes in the apparent dissociation constant for inhibition of neutrophil cathepsin G by thrombospondin 1. The inhibition constant increased > or = 10-14-fold following incubation of either Ca(2+)-replete or Ca(2+)-depleted thrombospondin 1 with protein disulfide isomerase and reduced glutathione. The rate of protein disulfide isomerase-catalyzed disulfide interchange in thrombospondin 1 increased linearly with protein disulfide isomerase concentration and the K(m) for reduced glutathione was 0.4 +/- 0.2 mM. Disulfide isomerization in both platelet and fibroblast thrombospondin 1 was probed by measuring perturbation in epitopes for two anti-thrombospondin 1 monoclonal antibodies. Antibody D4.6 binds to the C-terminal Ca(2+)-binding domains which are involved in disulfide interchange, whereas antibody HB8432 binds toward the N-terminus of the thrombospondin 1 subunit. In accordance with the location of these epitopes, incubation of platelet thrombospondin 1 or fibroblast thrombospondin 1 with protein disulfide isomerase and reduced glutathione resulted in 2-fold enhancement of binding of D4.6, whereas binding of HB8432 did not significantly change. In summary, protein disulfide isomerase catalyzes disulfide interchange in thrombospondin 1 which alters binding of neutrophil cathepsin G and antibody D4.6 to thrombospondin 1.
<i>E. coli</i>K-12 Asparaginase-Based Asparagine Biosensor for Leukemia (2007)

The present work aims at the development of a novel, diagnostic biosensor for monitoring asparagine levels in leukemia. Various immobilization strategies have been applied to improve the stability of the biocomponent (asparaginase). Response time studies have been carried out for different immobilization methods. Phenol Red indicator has been coimmobilized with asparaginase and color visualization approach has been optimized for various asparagine ranges. The detection limit of asparagine achieved with nitrocellulose membrane is 10(-1) M, with silicon gel is 10(-10)-10(-1) M, and with calcium alginate beads is 10(-9)-10(-1) M. Furthermore, the calcium alginate bead system of immobilization has been applied for the asparagine range detection in normal and leukemia serum samples.