gebhart/patrepeval huggingface dataset:
Modeling and adaptive open loop control of tunnel kilns (1985)

The thermal behaviour of countercurrent tunnel kilns used for instance in the ceramics industry for firing bricks or roofing tiles, can be modelled by a set of partial differential equations more or less complex according to the number of simplification asumptions. A sophisticated model is better for a system analysis but a simplified model allows a less difficult study of the automatic control of the kiln. This is why we first established a model giving temperature profiles through a kiln, knowing the distribution of control actions, and considering a small number of simplification asumptions. Then, we simplified this model by using several techniques such as linearization, functionnal approximation, singular perturbations. In order to solve a temperature profile regulation problem, we have determined an adaptive open loop control, derived from the application of the maximum principle. It consists of computing periodically the control variables from periodical measurements of the kiln temperature profile.
IL-33–Responsive Innate Lymphoid Cells Are an Important Source of IL-13 in Chronic Rhinosinusitis with Nasal Polyps (2013)

These data suggest a role for sinonasal epithelial cell-derived IL-33 and an IL-33-responsive innate lymphoid cell population in the pathophysiology of CRSwNP demonstrating the functional importance of innate lymphoid cells in Th2-mediated inflammatory disease.
From the guest editor medical data mining and knowledge discovery (2000)

Medical Data Mining and Knowledge Discovery * Legal Policy and Security Issues in the Handling of Medical Data * Medical Natural Language Understanding as a Supporting Technology for Data Mining in Healthcare * Anatomic Pathology Data Mining * A Data Clustering and Visualization Methodology for Epidemiological Pathology Discoveries * Mining Structure-Function Associations in a Brain Image Database * ADRIS * Knowledge Discovery in Mortality Records: An Info-Fuzzy Approach * Consistent and Complete Data and Expert Mining in Medicine * A Medical Data Mining Application Based on Evolutionary Computation * Methods of Temporal Data Validation and Abstraction in High-Frequency Domains * Data Mining the Matrix Associated Regions for Gene Therapy * Discovery of Temporal Patterns in Sparse Course-of-Disease Data * Data Mining-Based Modeling of Human Visual Perception * Discovery of Clinical Knowledge in Databases Extracted from Hospital Information Systems * Knowledge Discovery in Time Series.
Financial Literacy: An Overview of Practice, Research, and Policy (2002)

Attention to financial literacy has grown in recent years, in large part because technological, market, and legislative changes have resulted in a more complex financial services industry that requires consumers to be more actively involved in managing their finances. Consumer and community interest groups, banking companies, government agencies, and policymakers, among others, have become concerned that many consumers lack a working knowledge of financial concepts and the tools they need to make decisions most advantageous to their economic well-being. As a result, considerable resources have been devoted to financial literacy, with a wide range of organizations providing training, including banks, consumer and community groups, employers, and government agencies. Overall, studies suggest that financial literacy training can lead to better decisionmaking; however, the findings raise numerous questions about the best means of providing that training, the most appropriate setting, and the most opportune timing. Findings from recent research on personal money management styles, combined with awareness of human behavioral traits, offer insights that may be useful in developing successful training programs and strategies.
Sustaining availability of web services under distributed denial of service attacks (2003)

The recent tide of Distributed Denial of Service (DDoS) attacks against high-profile web sites demonstrate how devastating DDoS attacks are and how defenseless the Internet is under such attacks. We design a practical DDoS defense system that can protect the availability of web services during severe DDoS attacks. The basic idea behind our system is to isolate and protect legitimate traffic from a huge volume of DDoS traffic when an attack occurs. Traffic that needs to be protected can be recognized and protected using efficient cryptographic techniques. Therefore, by provisioning adequate resource (e.g., bandwidth) to legitimate traffic separated by this process, we are able to provide adequate service to a large percentage of clients during DDoS attacks. The worst-case performance (effectiveness) of the system is evaluated based on a novel game theoretical framework, which characterizes the natural adversarial relationship between a DDoS adversary and the proposed system. We also conduct a simulation study to verify a key assumption used in the game-theoretical analysis and to demonstrate the system dynamics during an attack.
An analytical method for maintenance outsourcing service selection (2004)

In this paper an experience dealing with the analysis of maintenance outsourcing by means of multi‐criteria decision methods (MCDM) is reported. In particular, the analytic hierarchy process technique (AHP) is used as a managerial decision support system to select the best alternative between different outsourcing contracts in terms of maintenance services. The proposed methodology has been tested on an industrial case study dealing with an important italian brickwork. This application shows how the AHP is able to support the choice of the correct level of the maintenance activities outsourcing. In particular, the hierarchic decisional structure developed represents an instrument able to give a well balanced synthesis of several different factors that must be taken into account during this type of decision problem.
Sensory neurons selectively upregulate synthesis and transport of the beta III-tubulin protein during axonal regeneration (1995)

The effects of peripheral nerve injury on the content, synthesis, and axonal transport of the class III beta-tubulin protein in adult rat dorsal root ganglion (DRG) neurons were examined. Recent reports of selective increases in the steady-state levels of the beta III-tubulin mRNA during axonal regeneration (Moskowitz et al., 1993) led to the hypothesis that upregulated levels of expression of the beta III-tubulin isotype that alter the composition of neuronal microtubules is important for effective axonal regrowth. If this is the case, the increases in mRNA levels must be translated into increased beta III-tubulin protein levels and subsequently modify the axonal cytoskeleton via axonal transport mechanisms. The present study assessed whether or not this occurs by examining beta III-tubulin protein content in adult rat lumbar DRG neurons at different times (1-14 d) after a distal sciatic nerve crush (approximately 55 mm from the DRG) by Western blotting and immunocytochemistry with a beta III-tubulin specific monoclonal antibody. These studies showed substantial increases in beta III-tubulin content in DRG neurons, as well as in proximal regions of peripheral sensory axons (0-6 mm from the DRG), from 1-2 weeks after a distal nerve injury. Pulse labeling of DRG neurons with 35S-methionine and 35S-cysteine and immunoprecipitation of labeled beta III-tubulin indicated that the synthesis of beta III-tubulin was increased in the DRG after axotomy. Studies of axonal transport, wherein L5 DRG proteins were labeled with 35S-methionine and 35S-cysteine by microinjection, revealed that slow component b(SCb) of axonal transport conveyed more labeled tubulin moving at apparently faster rates through the intact regions of sciatic nerve axons in response to crush injury of the distal sciatic nerve. Immunoprecipitation experiments using proximal peripheral nerve segments showed that SCb in distally injured DRG neurons was enriched in the beta III-tubulin isotype. These findings demonstrate that the augmented synthesis of beta III-tubulin after axotomy alters the composition of the axonally transported cytoskeleton that moves with SCb. The increased amounts and rate of delivery of beta III-tubulin in axons of regenerating DRG neurons suggest that the altered pattern of tubulin gene expression that is initiated by axotomy impacts on the composition and organization of the axonal cytoskeleton in a manner that can facilitate axonal regrowth.
Efficient Polar Code Construction for Higher-Order Modulation (2017)

An efficient algorithm for the construction of polar codes for higher-order modulation is presented based on information- theoretic principles. The bit reliabilities after successive demapping are estimated using the LM-rate, an achievable rate for mismatched decoding. The successive demapper bit channels are then replaced by binary input Additive White Gaussian Noise (biAWGN) surrogate channels and polar codes are constructed using a Gaussian approximation (GA). This LM-rate Demapper GA (LM-DGA) construction is used to construct polar codes for several demapping strategies proposed in literature. For all considered demappers, the LM-DGA constructed polar codes have the same performance as polar codes constructed by Monte Carlo (MC) simulation, but the LM-DGA construction is much faster. For 64-QAM, spectral efficiency 3 bits/s/Hz, and block length 1536 bits, simulation results show that LM-DGA constructed polar codes with cyclic redundancy check and successive cancellation list decoding are 1 dB more power efficient than state-of-the-art AR4JA low-density parity- check codes.
Site Prediction in Virgin Forests of Southeastern Alaska (1933)

Abstract The author discusses the climax forest in southeastern Alaska, its relation to even-aged stands, and the effect of logging and other factors on the succession from one to the other; he discusses also the possibility of applying ordinary yield table methods of site classification to these forests. The principles outlined are of interest to foresters in other regions particularly to those who axe concerned with the regeneration of mixed stands of spruce and balsam fir in the East.
The effect of annulation upon the solvatochromic behaviour of related merocyanines (1997)

The effect of annulation of the donor and/or the acceptor ring fragments of related merocyanines is discussed with the aid of a theoretical model based on semiempirical calculations performed with the AM1 method. The theoretical expectations are validated with examples of eight solvatochromic dyes described in the literature.
Epidermal Growth Factor Receptor Inhibition Prevents Caveolin-1-dependent Calcifying Extracellular Vesicle Biogenesis (2021)

Abstract Chronic kidney disease (CKD) increases the risk of cardiovascular disease, including vascular calcification, leading to higher mortality. Release of calcifying extracellular vesicles (EVs) by vascular smooth muscle cells (VSMCs) promotes the ectopic mineralization of vessel walls. Caveolin-1 (CAV1) protein plays a key role in genesis of calcifying EVs in VSMCs. Epidermal growth factor receptor (EGFR) co-localizes with and influences the intracellular trafficking of CAV1. Using a diet-induced mouse model of CKD, we measured serum EGFR and assessed the potential of EGFR inhibition to prevent vascular calcification. Mice with CKD developed widespread vascular calcification, which associated with increased serum levels of EGFR. We computationally analyzed 7651 individuals in the Multi-Ethnic Study of Atherosclerosis (MESA) and Framingham cohorts to assess potential correlations between coronary artery calcium and single nucleotide polymorphisms (SNPs) associated with elevated serum levels of EGFR. Individuals in the MESA and Framingham cohorts with SNPs associated with increased serum EGFR exhibit elevated coronary artery calcium. In both the CKD mice and human VSMC culture, EGFR inhibition significantly reduced vascular calcification by mitigating the release of CAV1-positive calcifying EVs. EGFR inhibition also increased bone mineral density in CKD mice. Given that EGFR inhibitors exhibit clinical safety and efficacy in other pathologies, the current data suggest that EGFR may be an ideal target to prevent pathological vascular calcification.
Code Performance as a Function of Block Size (1998)

The recent development of turbo codes has stirred new interest in trying to understand how closely practical codes can approach the theoretical limits on code performance. This article reformulates Shannon’s sphere-packing bound in a normalized form conducive to analyzing the relative performance of families of turbo codes. Even though this bound is achievable only by a (generally mythical) perfect spherical code for the continuous-input additive white Gaussian noise (AWGN) channel, it still can serve as a useful performance benchmark against which all codes of a given rate r and information block size k can be compared. A measure of imperfectness relative to this bound is defined and evaluated for a family of turbo codes and several other well-known codes. Simulations show that these turbo codes approach perfectness closely (within 0.7 dB) and almost uniformly over a wide range of code rates and block sizes. The implication is that turbo codes are near-optimal codes even for block sizes much smaller than previously believed. Finally, the sphere-packing lower bound also is compared to the average performance of randomly selected codes for the continuous-input AWGN channel and to an upper bound on the average performance of randomly selected codes for the binary-input AWGN channel.
Location-Based Services: The State of the Art (2003)

The convergence of the Internet and wireless telecommunications has opened the way for a plethora of data services for the mobile handset user. One potential area of mobile (m-) commerce development is in location-based services (LBS). Using a range of positioning techniques, operators can offer entirely new services and improvements on current ones. Popular examples cited include emergency caller location, asset tracking, navigation, location-based information or geographically sensitive billing. This paper examines the technologies, applications and strategic issues associated with the commercialization of LBS. The paper concludes with some predictions on the role of LBS in m-commerce.
2',5'-Oligoadenylates and related 2',5'-oligonucleotide analogs. 2. Effect on cellular proliferation, protein synthesis, and endoribonuclease activity (1983)

A number of the new enzymatically synthesized 2',5'-oligonucleotide trimers, namely, those containing the nucleosides 8-azaadenosine, toyocamycin, sangivamycin, formycin, 8-bromoadenosine, tubercidin, and guanosine, were found to inhibit protein synthesis and cellular proliferation after uptake into intact L and HeLa cells. 2',5'-Oligonucleotide trimers containing cytidine, inosine, uridine, and 1,N6-ethenoadenosine had some effect while those containing 2-chloroadenosine, 3-ribosyladenine, ribavirin, and 2-beta-D-ribofuranosylthiazole-4-carboxamide had no detectable effect on protein synthesis or cellular proliferation after uptake into L or HeLa cells. All of these 2',5'-oligonucleotide analogues inhibited protein synthesis in the in vitro rabbit reticulocyte lysate system except for the trimer containing ribavirin. Such nucleoside substitutions have further defined the substrate-specificity requirements for the endoribonuclease and/or the inhibitors for the 2',5'-phosphodiesterase. Most of the 2',5'-analogues were degraded in L-cell extracts so the endogenous nucleases are not very specific. The 2',5'-trimers containing tubercidin and 2-beta-D-ribofuranosylthiazole-4-carboxamide were quite stable in comparison to the 2',5'-A trimer. The inhibition of protein synthesis and cellular proliferation observed correlated well with the degradation of rRNA and polyadenylated mRNA observed after uptake of the 2',5'-analogues into intact L cells. The degradation of the polyadenylated mRNA appeared to be a more sensitive test than inhibition of cellular protein synthesis for determining biological activities of the 2',5'-oligonucleotide analogues.
A reusable lexical database tool for machine translation (1992)

This paper describes the lexical database tool LOLA (Linguistic-Oriented Lexical database Approach) which has been developed for the construction and maintenance of lexicons for the machine translation system LMT. First, the requirements such a tool should meet are discussed, then LMT and the lexical information it requires, and some issues concerning vocabulary acquisition are presented. Afterwards the architecture and the components of the LOLA system are described and it is shown how we tried to meet the requirements worked out earlier. Although LOLA originally has been designed and implemented for the German-English LMT prototype, it aimed from the beginning at a representation of lexical data that can be reused for other LMT or MT prototypes or even other NLP applications. A special point of discussion will therefore be the adaptability of the tool and its components as well as the reusability of the lexical data stored in the database for the lexicon development for LMT or for other applications.
Towards atomic force microscopy up to 100 MHz (2002)

An atomic force microscope for nanocantilevers measuring from a few 100 nm to a few μm in length was implemented. The natural frequencies of the nanocantilevers lie in the range of 1 MHz to 1 GHz, and optical detection schemes adapted to their size and frequency range was selected. A helium neon laser with a beat frequency of 890 MHz was used as the laser source. The beat was shifted to 1090 MHz by an acousto-optical-modulator, and used as the carrier for heterodyne laser Doppler measurement. This enabled velocity measurement up to around 100 MHz. The probe beam of the Doppler interferometer was guided to the nanocantilever by a single mode polarization-maintaining optical fiber terminated by a collimating lens, a quarter wave plate, and a focusing lens. Reflected light was collected by the same optics and mixed with the reference beam. Self-excitation of the nanocantilever at its lowest natural frequency was implemented for an amplitude of 1 nmp-p at 36 MHz. The Q factor of the cantilever was 8000. Noise effective amplitude of the Doppler interferometer was smaller than 10 pmp-p above 10 MHz. Frequency detection was possible for a nanowire measuring 100 nm in width.
Multiphase Bubbly Flow Visualization Using Particle Image Velocimetry (2002)

This article describes advances made in using particle image velocimetry (PIV) techniques in the study of multiphase bubbly flow. One of the fundamental issues in bubbly flow is the prediction of the velocity field. A methodology that allows for velocity field measurements of both components of a two-phase bubbly flow is presented. The bubble shape is also constructed via a shadow imaging technique combined with PIV.
Transition jitter estimates in tilted and conventional perpendicular recording media at 1 tb/in<sup>2</sup> (2003)

The recent proposal of tilted perpendicular recording for Tb/in <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> densities is extended here to examine the effects of intergranular exchange and anisotropy distributions on signal-to-noise ratio. This new recording system includes the single pole head, the medium and the soft underlayer as in perpendicular recording, but the medium anisotropy axes are titled at about 45°, optimally in the crosstrack direction. Both analytical formulas and micromagnetic simulations are utilized and both tilted and conventional perpendicular media are considered. At 1.2 Tb/in <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> exchange optimization and suitable anisotropy distribution limits give percentage transition jitter of 10% and 30% for tilted and conventional perpendicular media, respectively.
Effects of the combination of TRC105 and bevacizumab on endothelial cell biology (2014)

Endoglin, or CD105, is a cell membrane glycoprotein that is overexpressed on proliferating endothelial cells (EC), including those found in malignancies and choroidal neovascularization. Endoglin mediates the transition from quiescent endothelium, characterized by the relatively dominant state of Smad 2/3 phosphorylation, to active angiogenesis by preferentially phosphorylating Smad 1/5/8. The monoclonal antibody TRC105 binds endoglin with high avidity and is currently being tested in phase 1b and phase 2 clinical trials. In this report, we evaluated the effects of TRC105 on primary human umbilical vascular endothelial cells (HUVEC) as a single agent and in combination with bevacizumab. As single agents, both TRC105 and bevacizumab efficiently blocked HUVEC tube formation, and the combination of both agents achieved even greater levels of inhibition. We further assessed the effects of each drug on various aspects of HUVEC function. While bevacizumab was observed to inhibit HUVEC viability in nutrient-limited medium, TRC105 had little effect on HUVEC viability, either alone or in combination with bevacizumab. Additionally, both drugs inhibited HUVEC migration and induced apoptosis. At the molecular level, TRC105 treatment of HUVEC lead to decreased Smad 1/5/8 phosphorylation in response to BMP-9, a primary ligand for endoglin. Together, these results indicate that TRC105 acts as an effective anti-angiogenic agent alone and in combination with bevacizumab.
Cobalt(II)-facilitated transport of dioxygen in a polystyrene membrane (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCobalt(II)-facilitated transport of dioxygen in a polystyrene membraneM. J. Barnes, R. S. Drago, and K. J. BalkusCite this: J. Am. Chem. Soc. 1988, 110, 20, 6780–6785Publication Date (Print):September 1, 1988Publication History Published online1 May 2002Published inissue 1 September 1988https://pubs.acs.org/doi/10.1021/ja00228a028https://doi.org/10.1021/ja00228a028research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts