gebhart/patrepeval huggingface dataset:
Traffic Volume Data Outlier Recovery via Tensor Model (2013)

Traffic volume data is already collected and used for a variety of purposes in intelligent transportation system (ITS). However, the collected data might be abnormal due to the problem of outlier data caused by malfunctions in data collection and record systems. To fully analyze and operate the collected data, it is necessary to develop a validate method for addressing the outlier data. Many existing algorithms have studied the problem of outlier recovery based on the time series methods. In this paper, a multiway tensor model is proposed for constructing the traffic volume data based on the intrinsic multilinear correlations, such as day to day and hour to hour. Then, a novel tensor recovery method, called ADMM-TR, is proposed for recovering outlier data of traffic volume data. The proposed method is evaluated on synthetic data and real world traffic volume data. Experimental results demonstrate the practicability, effectiveness, and advantage of the proposed method, especially for the real world traffic volume data.
NEUE HOLLAENDISCHE METHODE FUER DIE BERECHNUNG VON BELASTUNGEN AUF ERDVERLEGTE ROHRE UND IHRE STATIK (1987)

BEI DER VEROEFFENTLICHUNG HANDELT ES SICH UM DIE NIEDERSCHRIFT EINES VORTRAGES. ER IST EINEM RECHNUNGSPROGRAMM GEWIDMET, DAS VON DER HOLLAENDISCHEN STIFTUNG ZUR FORSCHUNG UND QUALITAETSENTWICKLUNG FUER BETON IN ZUSAMMENARBEIT MIT DER TU DELFT UND EINEM INGENIEUR-BUERO ENTWICKELT WURDE. DER GANG DER BERECHNUNG WIRD AUS TABELLEN ERSICHTLICH. FOLGENDE EINZELHEITEN SIND BEDEUTSAM: DIE VERSCHIEDENEN ROHRMATERIALIEN WERDEN DURCH IHRE SYSTEMSTEIFIGKEIT E CHARAKTERISIERT. FUER STAHLBETONROHRE IST DIE RISSWEITE BESTIMMEND FUER DIE DIMENSIONIERUNG, FUER BETONROHRE DIE BRUCHLAST. DER BODEN UEBER, NEBEN UND UNTER DEM ROHR WIRD DURCH JEWEILS EINEN EIGENEN E-MODUL IN DIE BERECHNUNG EINGEFUEHRT. AUS DEM RECHENPROGRAMM GEHT SEHR DEUTLICH DER GUENSTIGE EINFLUSS EINER GUT VERDICHTETEN ROHRBETTUNG (GROESSERER AUFLAGERWINKEL) UND ROHRGRABENVERFUELLUNG HERVOR. ROHREIGENGEWICHT UND ROHRFUELLUENG ERGEBEN FUER DIE BEMESSUNG NUR EINEN VERNACHLAESSIGBAR KLEINEN EINFLUSS. DER SICHERHEITSGRAD WIRD IN DREI STUFEN FESTGELEGT: SOFERN BEIM BRUCH EINES ROHRES KEINE MENSCHENLEBEN IN GEFAHR KOMMEN UND DIE WIEDERHERSTELLUNG EINFACH IST, WIRD DIE NIEDRIGSTE SICHERHEITSSTUFE ANGENOMMEN (N=1,2). AUCH FUER ANDERE ROHRFORMEN (FUSSROHRE, EIPROFIL) KANN DAS PROGRAMM VERWENDET WERDEN. DURCH DIE ANWENDUNG DES PROGRAMMS KOENNEN RASCH WIRTSCHAFTLICHE VARIANTEN FUER DIE BAUAUSFUEHRUNG BEI AUSREICHENDER SICHERHEIT GEFUNDEN WERDEN.
The T Assessment Tool: A Simple Metric for Assessing Multidisciplinary Graduate Education (2010)

Although there is considerable activity in developing assessment protocols for undergraduate learning, there are few established models for assessment of student progress in multidisciplinary doctoral‐level graduate education. To resolve this impediment in tracking graduate student development, we created a simple assessment tool based on the concept of T competency that allows graduate students to articulate explicit learning goals in disciplinary and multidisciplinary research. Our instrument allows quantitative measurement of a student's self‐perception of his/her knowledge and interest in multidisciplinary inquiry. We use our T assessment tool to measure graduate student progress in an NSF IGERT‐funded graduate program in coastal ecosystem management. The T model provides us a nomenclature to articulate learning goals, a quantitative means to evaluate current and future learning targets and progress in reaching those targets, and gives us another measure of assessing overall graduate program effectiveness. Our T tool is an instrument that should have considerable utility in measuring knowledge and interest in multidisciplinary research across a range of disciplines and graduate programs.
Polymer waveguides and devices (2003)

We have investigated two kinds of polymeric thermo-optical (TO) components, i.e. a 1×8 digital TO switch relying on adiabatic mode evolution and a TO tunable filter using a thermally-controlled arrayed-waveguide grating (AWG). Cross-linked waveguides are developed to have low insertion loss, polarization independence, moisture insensitivity, and thermo-stability. The 1×8 TO switch is composed of seven 1×2 switch elements in a tree configuration, which we designed with a wide branching angle and a short heater length.
Combined Image Processing Techniques for Characterization of MRI Cartilage of the Knee (2005)

A common manifestation of osteoarthritis (OA) of the knee is the morphological degeneration of articular cartilage. In vivo magnetic resonance imaging (MRI) offers the potential to visualize and analyze quantitatively morphology such as cartilage thickness and volume. The purpose of this work was the development of new image processing techniques and application of existing ones for the intra and inter-subject quantitative analysis of cartilage of the knee. The process consists of MRI acquisition, cartilage segmentation, shape-based interpolation of segmented cartilage, segmentation of bone, volume registration based on bone structures, analysis, and visualization. The process is semi-automatic, the segmentation which is based on Bezier splines and edge detection requires interaction. Different shape interpolation methods were compared. The registration is based on shape matching and can be rigid-body and elastic. The analysis comprises cartilage volume and thickness calculations. The visualization allows the depiction of cartilage thickness maps overlaid on MR images or in three dimensions (3D). The cartilage segmentation and shape-based interpolation techniques were validated visually and based on the volumetric measurements of images of porcine knees which cartilage volume were directly measured using a saline displacement method. The registration technique was validated visually and using manual landmark registration.
Endotoxin in blood products: correlation between the Limulus assay and the rabbit pyrogen test. (1985)

The possibility of replacing the rabbit pyrogen test by the Limulus (LAL) test, as a final release test for plasma products, was investigated. The LAL test measured the endotoxin content quantitatively, using a chromogenic substrate. The samples were boiled and centrifuged to remove inhibiting substances, which represent a major problem when testing plasma protein samples. In order to correlate the LAL test to the rabbit test, parallel assays were performed on 85 batches of two different human albumin preparations. For both products, a positive correlation was observed between the two tests. However, the pass/fail limit of the rabbit test was found at different endotoxin levels, corresponding to about 2 and 20 ng/kg, respectively. This discrepancy could be removed by extracting the endotoxin before administration to rabbits. It is concluded that the endotoxin, detected in plasma products by the LAL test, may be present in a non-pyrogenic state.
Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic <i>Escherichia coli</i> (2010)

Extraintestinal pathogenic Escherichia coli (ExPEC) are a common cause of disease in both mammals and birds. A vaccine to prevent such infections would be desirable given the increasing antibiotic resistance of these bacteria. We have determined the genome sequence of ExPEC IHE3034 (ST95) isolated from a case of neonatal meningitis and compared this to available genome sequences of other ExPEC strains and a few nonpathogenic E. coli. We found 19 genomic islands present in the genome of IHE3034, which are absent in the nonpathogenic E. coli isolates. By using subtractive reverse vaccinology we identified 230 antigens present in ExPEC but absent (or present with low similarity) in nonpathogenic strains. Nine antigens were protective in a mouse challenge model. Some of them were also present in other pathogenic non-ExPEC strains, suggesting that a broadly protective E. coli vaccine may be possible. The gene encoding the most protective antigen was detected in most of the E. coli isolates, highly conserved in sequence and found to be exported by a type II secretion system which seems to be nonfunctional in nonpathogenic strains.
Co-assembly of aromatic dipeptides into spherical structures that are similar in morphology to red and white blood cells (2014)

This paper describes the co-assembly of two aromatic dipeptides, diphenylalanine and Fmoc-l-DOPA(acetonated)-d-Phe-OMe, into different spherical structures that are similar in morphology to either red or white blood cells. Under the examined experimental conditions, each of the peptides formed spherical nanostructures, but a mixture of the two peptides generated new types of assemblies. When the concentration of the two peptides was 1 mg mL<sup>-1</sup> they self-assembled into oval biconcave disk nanostructures that are similar in morphology to red blood cells. When the concentration of the peptides was higher they formed spherical structures with bulges on their outer surface. These assemblies are similar in morphology to white blood cells. We determined the morphology and structure of the assemblies using atomic force microscopy and electron microscopy and their secondary structure using ATR-FTIR and CD. In addition, we studied the co-assembly of Fmoc-DOPA(acetonated)-d-Phe-OMe with other diphenylalanine analogues. Furthermore, we showed that the red blood cell-like structures can adsorb and release the anticancer drug, doxorubicin, and therefore might be useful as a system for sustained drug release.
The synthesis of multiple O-phosphoseryl-containing peptides via phenyl phosphate protection (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe synthesis of multiple O-phosphoseryl-containing peptides via phenyl phosphate protectionJohn W. Perich and R. B. JohnsCite this: J. Org. Chem. 1988, 53, 17, 4103–4105Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/jo00252a041https://doi.org/10.1021/jo00252a041research-articleACS PublicationsRequest reuse permissionsArticle Views267Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Delta-4 approach to dependability in open distributed computing systems (1988)

As part of the European Strategic Programme for Research in Information Technology (ESPRIT), the Delta-4 project is seeking to define an open, fault-tolerant, distributed computing architecture. The authors present the overall Delta-4 framework for open, fault-tolerant, distributed computing systems and sketch the current implementation, which is based on a local area network with specific atomic multicasting and error-processing protocols for communicating between replicated software components. The system is used to demonstrate the various fault-tolerance techniques by a replicated database application.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The export systems of type 1 and F1C fimbriae are interchangeable but work in parental pairs (1995)

Type 1 and F1C fimbriae are surface organelles of Escherichia coli which mediate receptor-specific binding to different host surfaces. Such fimbriae are found, among others, on strains associated with urinary tract infections. Biosynthesis of type 1 and F1C fimbrial organelles requires individual, specialized two-component assembly systems. The organization of the fim and foc gene clusters encoding these fimbriae, as well as the structure of the organelles, is very similar; however, the actual sequence homology of the structural elements is not remarkable (34 to 60%). Both gene clusters encode a periplasmically located chaperone and an usher protein, located in the outer membrane, required for organelle biogenesis. Deletion of either element causes abolishment of fimbriation. The present report addresses the question of promiscuity in fimbrial biogenesis. Our data indicate that the two-component export systems of the two organelle systems are reciprocally interchangeable; however, they seem to function only in parental pairs.
Hybrid techniques for analog function generation (1963)

In computing systems involving real-time simulation, data processing, or control, it is often possible to combine digital and analog computing techniques to improve the over-all system capability or performance. Effective combinations of analog and digital techniques have been made at several levels. At the systems level, general-purpose digital and analog machines have been linked through conversion equipment, enabling more effective solution of classes of problems which involve both precision arithmetic operations and rapid solution of differential equations. At the component level the capabilities of digital equipment for information storage, logical decisions, and sequence generation can be used in a variety of ways to augment the capabilities of analog equipment for wideband computation. Finally, at the information representation level, hybrid codes have been utilized to represent variables to obtain high-accuracy computing structures from an assembly of less accurate components.
Compact electric field sensors based on indirect bonding of lithium niobate to silicon microrings (2012)

An electric field sensor based on the indirect bonding of submicrometer thin films of lithium niobate to silicon microring resonators is presented using benzocyclobutene as an intermediate bonding layer. The hybrid material system combines the electro-optic functionality of lithium niobate with the high-index contrast of silicon waveguides, enabling compact and metal-free electric field sensors. A sensor is designed and fabricated using ion-sliced z-cut lithium niobate as the top cladding of a 20 μm radius silicon microring resonator. The optical quasi transverse magnetic mode is used to access the largest electro-optic coefficient in the lithium niobate. Optical characterization of the hybrid device results in a measured loaded quality factor of 13,000 in the infrared. Operation of the device as an electric field sensor is demonstrated by detecting the fringing fields from a microstrip electrical circuit operating at 1.86 GHz. The demonstrated sensitivity to electric fields is 4.5 V m-1 Hz-1/2.
Dynamic RARP Extensions for Automatic Network Address Acquisition (1996)

This memo describes extensions to the Reverse Address Resolution
Protocol (RARP [2]) and called Dynamic RARP (DRARP, pronounced
D-RARP). This memo provides information for the Internet community.
This memo does not define an Internet standard of any kind.
A Novel Voltage-to-Voltage Logarithmic Converter with High Accuracy (2011)

Abstract — A novel BiCMOS voltage-to-voltage converter with logarithmic characteristics and very high accuracy is presented. The relationship between the emitter current and the base-emitter voltage in bipolar transistors is used to realize the logarithmic function. With 1.8 supply voltage, the total power consumption is less than 15.75 mW and an error of &lt;-36dB is shown in the ADS simulations. Compared to the other method in the literature, very better accuracy in logarithm calculation is achieved. The proposed method can be used in arithmetical operation circuits like analog processors. Index Terms — Arithmetical circuits, Logarithmic Amplifier, Logarithmic converter. each stage is generated by taking advantage of a transconductance element. The summation of all these currents with proper transconductance ratio can approximate the logarithmic function piecewise. With a little systematic difference with the previous method, the parallel amplification type circuit was used in [7],[8]. Fig. 2 presents the system diagram of this approach. High symmetry in different path which is lead to the good phase and group delay matching is the strength of this method, while its input dynamic range is lower than the previous on [1]. L I.
Shock-Protection Improvement Using Integrated Novel Shock-Protection Technologies (2011)

This paper presents the design and results of shock experiments conducted to demonstrate the advantages of two novel shock-protection technologies: 1) nonlinear spring shock stops and 2) soft coating shock stops. Both technologies basically employ the conventional idea of hard shock stops to decouple device design from shock-protection design but are specialized to reduce impact force, which is one of the drawbacks of hard stops. In addition, they enable wafer-level and batch fabrication processes compatible with microfabrication techniques. We designed test devices to reflect the effect of impact force and fabricated them using silicon microbeams (nonlinear springs) or Parylene coating (soft coating). After conducting multiple shock tests (up to 2500 g), we demonstrate that the shock-survival rates of test devices are considerably improved in both our novel technologies (nonlinear spring: 88%, soft coating: 94%) compared to conventional hard stops (4%). Moreover, we demonstrated that shock protection is improved by optimizing the design of shock springs. Finally, we analyzed dynamics of flexible beams and identified a new device-fracture mechanism induced by impact force, which is different from conventionally known mechanisms.
Electrospun scaffolds from silk fibroin and their cellular compatibility (2009)

Electrospinning offers an attractive opportunity for producing silk fibroin (SF) nano/micro fibrous scaffolds with potential for tissue regeneration and repair. Electrospun scaffolds of silk fibroin were fabricated as a biomimetic scaffold for tissue engineering. The morphology of the electrospun scaffolds was investigated with SEM and AFM. The SEM images indicated that electrospun SF fibers were ribbon-shaped and the average width increased with increasing SF concentrations. The AFM images revealed that, after treated with methanol, there was a groove on the surface of fiber, which is conducive to cell attachment. The structure of electrospun SF fibers was characterized by NMR, WAXD, and DSC. The results displayed that SF in electrospun fibers was present in a random coil conformation, SF conformation transformed from random coil to beta-sheet when treated with methanol. Cell attachment and proliferation studies with pig iliac endothelial cells (PIECs) demonstrated that electrospun SF scaffolds significantly promoted cell attachment and proliferation in comparison with cast SF films. These results suggest electrospun SF scaffolds may be potential candidates for cardiovascular tissue engineering.
Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells (2012)

The IL-18 induction of BACE-1, APP processing, and Aβ is likely to be linked to stress-associated adaptations in neurons during the course of normal functioning and development. However, in the course of wider changes in the aging brain, and particularly in AD, the effects of heightened or prolonged levels of IL-18 may contribute to the process of AD, including via increased Aβ.
Predicting Extractives and Lignin Contents in<i>Eucalyptus globulus</i>Using Near Infrared Reflectance Analysis (2004)

Lignin and extractive content are important determinants of the pulping quality of wood. Determination of extractive and lignin content using traditional chemical methods is a costly and time-consuming process. Near infrared reflectance (NIR) analysis offers a low cost alternative for prediction of wood quality. Calibrations were developed for the prediction of extractives content, acid-soluble lignin, Klason lignin, and total lignin contents. Each calibration had standard errors of less than 0.6%. Laboratory measurements for a separate set of samples were highly correlated with predicted values (R2 of 0.89 for extractives content, 0.83 for acid-soluble lignin content, 0.97 for Klason lignin content, and 0.99 for total lignin content). It was concluded that NIR analysis is a reliable predictor of extractive and lignin content in Eucalyptus globulus.
Sodium Pancratistatin 3,4-<i>O</i>-Cyclic Phosphate, a Water-Soluble Synthetic Derivative of Pancratistatin, Is Highly Effective in a Human Colon Tumor Model (2007)

Sodium pancratistatin 3,4- O-cyclic phosphate ( 2) is a novel water-soluble synthetic derivative of pancratistatin ( 1), a natural alkaloid constituent of Amaryllidaceae plants, that exhibits good cytostatic and antineoplastic activity but is highly insoluble. Unlike most other natural alkaloids it does not act by binding to tubulin, and its mechanism of action has yet to be fully elucidated. Here the efficacy of 2 in a human colon adenocarcinoma model, DLD-1, and some understanding of its mode of action are investigated. Agreeing with previous studies, low cytotoxicity in vitro was seen for 2 with IC 50's of 253 and 19.7 microM for 1 and 96 h exposures, respectively. However in vivo the compound caused statistically significant tumor growth delays ( p < 0.01) at its maximum tolerated dose, and significant vascular shutdown and tumor necrosis were observed. Like 1, the compound appeared to have an unconventional mechanism of action with no effect on microtubule structure, yet causing a G 2/M block, while it was seen to disrupt mitochondrial function. The mechanism of action of 1 and 2 appears to be similar. Thus compound 2, being considerably more soluble than 1, has good potential as an anticancer agent, and further investigation is warranted.
Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12 (2000)

When C2C12 pluripotent mesenchymal precursor cells are treated with transforming growth factor beta1 (TGF-beta1), terminal differentiation into myotubes is blocked. Treatment with bone morphogenetic protein 2 (BMP-2) not only blocks myogenic differentiation of C2C12 cells but also induces osteoblast differentiation. The molecular mechanisms governing the ability of TGF-beta1 and BMP-2 to both induce ligand-specific responses and inhibit myogenic differentiation are not known. We identified Runx2/PEBP2alphaA/Cbfa1, a global regulator of osteogenesis, as a major TGF-beta1-responsive element binding protein induced by TGF-beta1 and BMP-2 in C2C12 cells. Consistent with the observation that Runx2 can be induced by either TGF-beta1 or BMP-2, the exogenous expression of Runx2 mediated some of the effects of TGF-beta1 and BMP-2 but not osteoblast-specific gene expression. Runx2 mimicked common effects of TGF-beta1 and BMP-2 by inducing expression of matrix gene products (for example, collagen and fibronectin), suppressing MyoD expression, and inhibiting myotube formation of C2C12 cells. For osteoblast differentiation, an additional effector, BMP-specific Smad protein, was required. Our results indicate that Runx2 is a major target gene shared by TGF-beta and BMP signaling pathways and that the coordinated action of Runx2 and BMP-activated Smads leads to the induction of osteoblast-specific gene expression in C2C12 cells.