gebhart/patrepeval huggingface dataset:
A 1-V BiCMOS rail-to-rail amplifier with n-channel depletion mode input stage (1997)

A BiCMOS rail-to-rail operational amplifier capable of operating from supply voltages as low as 1 V is presented. The folded cascode input stage uses an nMOS depletion mode differential pair to provide rail-to-rail common mode voltage range while typically requiring only 40 fA of input bias current. The bipolar transistor differential-to-single-ended conversion network employs a low-voltage base current cancellation technique which provides high input stage voltage gain from a l-V supply yet allows a 3-V//spl mu/s slew rate capability. The bipolar transistor output stage uses a low-voltage translinear loop which maintains a low impedance signal path to the output common emitter power devices. This circuit topology enables the amplifier to achieve a 4-MHz bandwidth with 60/spl deg/ of phase margin. The output voltage can swing to within 50 mV of each supply rail. An "on-demand" base current boost technique will be presented which can provide up to 50 mA of output drive capability from a 5-V supply, yet consumes only a few microamps when the output is in the quiescent state. A low voltage level shift technique will be described which uses an n-channel depletion mode source follower to provide isolation between the input and output stages.
Cellular and Molecular Mechanisms of Mesenchymal Stem Cell Actions (2017)

The clinical interest in the therapeutic use of mesenchymal stromal/stem cells (MSC) is further increasing as their versatility in animal trial settings becomes more and more obvious. Indeed, screening the official review site for clinical trials (http://www.clinicaltrials.gov) using the search term “Mesenchymal Stem Cells” reveals 611 records (September, 2017). The large diversity of medical indications for treatment with MSC comprises hematological malignancies, diabetes type 1, neurologic diseases, joint and bone diseases, organ transplantation, or liver diseases, just to mention a small selection. This indicates the big potential of MSC to act beneficially both on chronic and acute diseases of either local or systemic origin. However, albeit we are only starting to understand the mode of action of MSC in certain disease conditions, there is still hesitation on the safety, upscale feasibility and, effectiveness of clinical MSC application.
Fluorescent Whitening Agents (1974)

Sulfonated aromatic aldehydes strongly sensitize the yellowing of wool by simulated sunlight, especially for exposure in the wet state. Compounds of this class are formed when stilbene-type fluorescent whitening agents are irradiated, either in solution or on wool. The possibility that these sulfonated benzaldehyde derivatives are responsible for the accelerated photoyellowing of fluorescently whitened wool is discussed. It is concluded that they may be important in the photoyellowing of whitened fabrics in the wet state, although they play little part in the photoyellowing of dry fabrics.
Using CT to Localize Side and Level of Vocal Cord Paralysis (2003)

Three reliable imaging findings associated with vocal cord paralysis were identified on routine axial CT studies: ipsilateral pyriform sinus dilatation, medial positioning and thickening of the ipsilateral aryepiglottic fold, and ipsilateral laryngeal ventricle dilatation. Coronal reformatted images of the larynx may be helpful, but they are not necessary in 95% of patients. Ipsilateral pharyngeal constrictor muscle atrophy is a helpful imaging finding to localize a more central vagal neuropathy. Our findings can aid radiologists in identifying peripheral and central vagal neuropathy in patients who present for CT of the neck who have a normal voice and are without a history suggestive of a vagal problem.
Mapping of HPV-11 E1 Binding Site and Determination of Other ImportantcisElements for Replication of the Origin (1996)

The viral proteins E1 and E2 are essential for the replication of the HPV-11 origin. We have now mapped the E1 binding site (E1BS) and show by mutation analysis that the E1BS and an adjoining poly(A)-rich region are necessary for efficient replication of the origin. We have also shown, using suboptimal levels of E1 protein, that enhancement of E1 binding by E2 partially protects the E1BS. Finally, we show that E1 can enhance the binding of E2 even in the absence of the E1BS.
Reduction of SAR digital processing time using vector quantization (2003)

A procedure is presented to directly process synthetic-aperture radar (SAR) phase history data in a vector-quantized form. The procedure is particularly valuable when SAR has previously been vector-quantized to reduce bandwidth for downlink or other purposes. The vector quantization (VQ) process necessarily degrades the image, the degradation being generally a direct function of VQ compression ratio. However, the individual quality measures are affected differently. The computation compression technique (CCT) described is faster because only addition is required, as contrasted with both multiplication and addition for the FFT. The fact that preprocessed segments are overlapped and summed lends itself to parallel processing. Parameters for using CCT are the size of each vector, whether 1-D or 2-D, the number of entries in the codebook, and the address bits. These parameters influence the amount of time savings, image degradation, and amount of required memory.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The CMS Muon detectors (2007)

The compact muon solenoid (CMS) is a multipurpose detector at the large hadron collider (LHC) at CERN. One of the main goals of the CMS design is to ensure efficient and accurate identification and reconstruction of muons. The CMS muon spectrometer is based on three kinds of gaseous detectors placed inside the iron return yoke of a 4 Tesla superconducting solenoid: Drift Tube Chambers (DT), Cathode Strip Chambers (CSC) and the Resistive Plate Chambers (RPC). The detector is currently being assembled and commissioned with cosmics to be ready to take data in 2008. At the end of 2006 a fraction of the whole CMS including several sectors of the muon system were tested together with the magnet at the nominal field. A description of the main features of the system, with more emphasis on the DT detectors will be presented.
Detecting the Optic Disc Boundary in Digital Fundus Images Using Morphological, Edge Detection, and Feature Extraction Techniques (2010)

Optic disc (OD) detection is an important step in developing systems for automated diagnosis of various serious ophthalmic pathologies. This paper presents a new template-based methodology for segmenting the OD from digital retinal images. This methodology uses morphological and edge detection techniques followed by the Circular Hough Transform to obtain a circular OD boundary approximation. It requires a pixel located within the OD as initial information. For this purpose, a location methodology based on a voting-type algorithm is also proposed. The algorithms were evaluated on the 1200 images of the publicly available MESSIDOR database. The location procedure succeeded in 99% of cases, taking an average computational time of 1.67 s. with a standard deviation of 0.14 s. On the other hand, the segmentation algorithm rendered an average common area overlapping between automated segmentations and true OD regions of 86%. The average computational time was 5.69 s with a standard deviation of 0.54 s. Moreover, a discussion on advantages and disadvantages of the models more generally used for OD segmentation is also presented in this paper.
Hydroxylation of an Aliphatic C−H Bond in an Imidazole-Ligated (μ-η<sup>2</sup>:η<sup>2</sup>-Peroxo)dicopper(II) Complex (1997)

Low-temperature oxygenation of {Cu[P(imiPr2)3]CH3CN}CF3SO3 affords a μ-η2:η2-peroxo adduct. Upon warming a dilute solution (<10-3 M) of the peroxide complex, intramolecular hydroxylation occurs at the tertiary carbon atom of one of the isopropyl groups of the ligand, reminiscent of the one catalyzed by the copper enzyme dopamine β-monooxygenase.
A two-base-pair substitution in T7 promoter by SP6 promoter-specific base pairs alone abolishes T7 promoter activity but reveals SP6 promoter activity. (1992)

The phage T7 and SP6 RNA polymerase-promoter systems are very similar in many characteristics, but maintains stringent specificity for each. In order to identify the base pair element that distinguishes between T7 and SP6 promoters, the base pairs at -12, -10, -9, and -8 of the T7 promoter consensus sequence were changed singly and multiply to the SP6 promoter-specific base pairs, and assayed for T7 and SP6 promoter activities. The results indicate that the primary discrimination element is the base pairs at -8 and -9. The two-base-pair substitution alone in T7 promoter by SP6-specific base pairs is sufficient to make the T7 variant be a SP6 promoter, abolishing T7 promoter activity.
Putting your best foot forward (2012)

Foot-based gestures have recently received attention as an alternative interaction mechanism in situations where the hands are pre-occupied or unavailable. This paper investigates suitable real-world mappings of foot gestures to invoke commands and interact with virtual workspaces. Our first study identified user preferences for mapping common mobile-device commands to gestures. We distinguish these gestures in terms of discrete and continuous command input. While discrete foot-based input has relatively few parameters to control, continuous input requires careful design considerations on how the user's input can be mapped to a control parameter (e.g. the volume knob of the media player). We investigate this issue further through three user-studies. Our results show that rate-based techniques are significantly faster, more accurate and result if far fewer target crossings compared to displacement-based interaction. We discuss these findings and identify design recommendations.
Brain Tumor Segmentation and Survival Prediction Using Multimodal MRI Scans With Deep Learning (2019)

Gliomas are the most common primary brain malignancies. Accurate and robust tumor segmentation and prediction of patients' overall survival are important for diagnosis, treatment planning and risk factor identification. Here we present a deep learning-based framework for brain tumor segmentation and survival prediction in glioma, using multimodal MRI scans. For tumor segmentation, we use ensembles of three different 3D CNN architectures for robust performance through a majority rule. This approach can effectively reduce model bias and boost performance. For survival prediction, we extract 4,524 radiomic features from segmented tumor regions, then, a decision tree and cross validation are used to select potent features. Finally, a random forest model is trained to predict the overall survival of patients. The 2018 MICCAI Multimodal Brain Tumor Segmentation Challenge (BraTS), ranks our method at 2nd and 5th place out of 60+ participating teams for survival prediction tasks and segmentation tasks respectively, achieving a promising 61.0% accuracy on the classification of short-survivors, mid-survivors and long-survivors.
Maximum weights of lift acceptable to male and female industrial workers for extended work shifts (1984)

Abstract This paper reports the development of maximum acceptable weight of lift databases for male and female industrial workers for 12-hour work periods. Using a psychophysical methodology, 37 males and 37 females, experienced in manual lifting, performed various lifting tasks involving four frequencies, three box sizes, and three height levels. The maximum acceptable weight of lift was significantly influenced by the frequency of lift, height of lift, and box size. Box size effects were, however, less profound than frequency, and height effects. The maximum weight, acceptable for 12 hours of lifting, elicited an average heart rate of 90 and 101 beats min −1 for males and females, respectively. Males selected weights that, on average, resulted in metabolic energy expenditure rates of 23% of their aerobic capacity for 12 hours of lifting. Females required metabolic energy expenditure rates equivalent to 24% of their aerobic capacity for lifting acceptable levels of weight for 12 hours.
ACTOR GARBAGE COLLECTION IN DISTRIBUTED SYSTEMS USING GRAPH TRANSFORMATION (2021)

A lot of research work has been done in the area of Garbage collection for both uniprocessor and distributed systems. Actors are associated with activity (thread) and hence usual garbage collection algorithms cannot be applied for them. Hence a separate algorithm should be used to collect them. If we transform the active reference graph into a graph which captures all the features of actors and looks like passive reference graph then any passive reference graph algorithm can be applied for it. But the cost of transformation and optimization are the core issues. An attempt has been made to walk through these issues.
Video-mediated and co-present gameplay: Effects of mutual gaze on game experience, expressiveness and perceived social presence (2012)

We study how pairs of children interact socially and express their emotions while playing games in different communicative settings. In particular, we study how such interactions can vary for environments that differ regarding the level of mediation and the associated feelings of social presence. Overall, the study compared three conditions (one face-to-face gameplay condition, and two video-mediated gameplay conditions; one allowing for mutual gaze, the other not) and focused on the social presence and non-verbal behavior of children in three conditions. The results show that the presence of mutual eye-gaze enriches the feelings of social presence, fun and game experience; conversely, the absence of mutual eye-gaze dramatically effects the quality of interaction in the video-mediated environment. The results of this study stress the importance of mutual gaze, and we therefore argue that it should become an integral component of future VMC systems, particularly in those designed for playful settings and children.
Studies on Suppression of Hydrogen Evolution Reaction for Zinc/Air Fuel Cell (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Timing experiment with geodetic GPS receiver (1994)

In view of the availability of a new generation of geodetic GPS receivers coupled with the introduction of selective availability (SA) on the C/A-code, the use of these types of GPS receivers for timing applications has been extensively reviewed. The common-view mode shows an improvement in timing accuracy (15 to 25 ns) over the one-way mode (around 100 ns) even in the presence of SA. A model has also been introduced to reduce the detrimental effect of SA on the time accuracy even in the one-way mode. The utilization of this model on the experimental observations shows a remarkable reduction in jitter to about 20 ns.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Dynamic models for micro-turbines and fuel cells (2001)

Distributed resources (DR) include a variety of energy sources, such as micro-turbines, photovoltaics, fuel cells, and storage devices, with capacities in the 1 kW to 10 MW range. Deployment of DR on distribution networks could potentially increase their reliability and lower the cost of power delivery by placing energy sources nearer to the demand centers. By providing a way to by-pass conventional power delivery systems, DR could also offer additional supply flexibility. The trends in technology points toward smallness, under the 500 kW level. An example are the small gas fired micro-turbines in the 25-100 kW range that can be mass produced at low cost. Fuel cells are also well suited for distributed generation applications. There are two basic classes of micro-source systems; one is a DC source, such as fuel cells, photovoltaics, and battery storage, the other is a high frequency AC source such as the micro-turbine which needs to be rectified. Power electronic interfaces introduces new control issues and new possibilities. This paper discusses micro-turbine and fuel cell models, and the instanteous power issue. An inverter model is also presented.
Structural plasticity of substrate selection by activation‐induced cytidine deaminase as a regulator of its genome‐wide mutagenic activity (2020)

Activation-induced cytidine deaminase (AID) mediates somatic hypermutation and class-switch recombination of antibodies. Computational-biochemical and crystallography analyses of AID have identified three surface grooves for binding single-stranded DNA (ssDNA). Functional studies have also found evidence for RNA-binding motifs on AID. Although AID and the related apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) enzymes share a conserved core, AID uniquely features multiple substrate-binding motifs on its surface. Here we suggest that combinatorial deployment of AID's multiple ssDNA- or RNA-binding motifs yields many substrate-binding modes that can accommodate ssDNA, RNA, or DNA/RNA substrates of diverse structures. We also suggest that AID oligomerization generates yet additional novel substrate-binding modes. We propose that this plasticity in substrate choice is an evolved aspect of AID's structure that contributes to the regulation of its differential mutagenic activity at various loci.
Raman Spectroscopy of Monolayers Formed from Chromate Corrosion Inhibitor on Copper Surfaces (2003)

Surface enhanced Raman scattering (SERS) was used to observe interactions of dilute Cr^VI solutions with silver and copper surfaces in situ. Using silver as a model surface which supports strong SERS with a 514.5 nm laser, it was possible to observe Cr^III at the near monolayer level, and the spectra were compared to those from Cr^III oxyhydroxide species and Cr^III/Cr^VI mixed oxide. Similar experiments were conducted with Cu surfaces and 785 nm excitation. Upon exposure to Cr^VI solution, the characteristic Cu oxide Raman bands disappeared, and a Cr^III band increased in intensity over a period of ~20 h. The intensity of the Cr^III band on Cu became self-limiting after the formation of several Cr^III monolayers, as supported by chronoamperometry experiments. This Cr^III spectrum was stable after Cr^VI was removed from the solution provided the potential remained negative of –200 mV vs. Ag/AgCl. The results support the conclusion that Cr^VI is reductively adsorbed to Cu at the near neutral pH and open circuit potentials expected for Cu/Al alloys in field applications. The Cr^III film is stable and is a strong inhibitor of electron transfer in general and oxygen reduction in particular. An important mechanistic feature of Cr^III formation is the substitution lability of Cr^VI compared to Cr^III. The Cr^VI-O bond can be broken much more rapidly than the substitution inert Cr^III-O bond, making formation of Cr^III/Cr^VI mixed oxide kinetically favorable. Once reduced to Cr^III, however, the substitution inert oxyhydroxide film is much less labile. An important and central feature of Cr^VI as a corrosion inhibitor is its transformation via reductive adsorption from a mobile, substitution labile Cr^VI form to an insoluble, substitution inert Cr^III oxyhydroxide. Furthermore, Cr^VI reduction is likely to occur at cathodic sites previously responsible for oxygen reduction, which are then permanently blocked by a stable Cr^III film with a thickness of a few monolayers.
The Methylpyrroles. Synthesis and Characterization (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Methylpyrroles. Synthesis and CharacterizationR. L. Hinman and S. TheodoropulosCite this: J. Org. Chem. 1963, 28, 11, 3052–3058Publication Date (Print):November 1, 1963Publication History Published online1 May 2002Published inissue 1 November 1963https://pubs.acs.org/doi/10.1021/jo01046a030https://doi.org/10.1021/jo01046a030research-articleACS PublicationsRequest reuse permissionsArticle Views459Altmetric-Citations72LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Enzymatic amplification of HTLV-I viral sequences from peripheral blood mononuclear cells and infected tissues (1988)

Human T-cell lymphotropic virus type I (HTLV-I) and human T-cell lymphotropic virus type II (HTLV-II) have been associated with adult T- cell leukemia/lymphoma (ATL) and a rare T-cell variant of hairy cell leukemia, respectively. Direct detection of viral nucleic acid in peripheral blood lymphocytes (PBLs) and infected tissues in carrier patients and those with chronic disease has proven refractory due to viral transcriptional dormancy and the small number of infected cells present. The investigators report here the successful application of the DNA amplification procedure, termed PCR, to the detection of these human oncoviruses. Judicious selection of specific oligonucleotides for primers and probes provides type-specific and simultaneous detection of these two retroviruses. The ability to amplify and detect highly conserved regions of these medically relevant viruses may facilitate the identification of, as yet, uncharacterized retroviruses.
Elevated expression of Cu, Zn‐SOD and Mn‐SOD mRNA in inflamed dental pulp tissue (2006)

The development of pulpitis is associated with elevated transcription of both Cu, Zn-SOD and Mn-SOD; pulp tissue inflammation generated higher Mn-SOD transcription compared with Cu, Zn-SOD.