gebhart/patrepeval huggingface dataset:
Single-Mode Fiber Printheads And Scanline Interleaving For High-Resolution Laser Printing (1989)

A multiple-laser-diode printhead using a close-spaced array of single-mode optical fibers has been developed for large-format, high-resolution laser printing. This head avoids the output interaction problems of multiple-laser arrays on a single GaAs substrate, while providing small spots, close spacing, low noise, and a compact assembly. Each of the separately packaged laser diodes is controlled by current modulation, and its emission is coupled into the input end of a single-mode optical fiber. The array is made by mounting the fibers in a crystailographically etched set of parallel V-grooves in a silicon wafer. The fibers are specially prepared to allow close spacing. Single-mode fibers are desirable because their outputs can be imaged to give diffraction-limited spots. Close spacing of the multiple sources is desirable because the imaging lens utilizes a smaller field of view and requires less demagnification to give closely spaced scanlines. In order to further reduce the spot spacing to increase spot overlap, the writing head can be tilted with respect to the scanning direction, or the exposure tracks can be interleaved. Tilting requires appropriate pixel-data delays and tighter tolerances on the planarity of the array. A new and more convenient method of interleaving has been developed.
The Linkage Region of Cartilage Keratan Sulfate to Protein (1974)

Abstract Glycopeptides derived from bovine nasal septum keratan sulfate by acid hydrolysis and gel chromatography are shown to be enriched in the carbohydrate-protein linkage region. The effects of alkali on these glycopeptides are compared to the effects on the starting material. It is shown that the β elimination caused by alkali is consistent with an O-glycosidic linkage between threonine or serine in the peptide and N-acetylgalactosamine in the carbohydrate chain. The glycopeptides were subjected to β elimination and reduction. The galactosamine destroyed by this treatment was converted to its reduced analog and the expected reduction products derived from serine and threonine were also formed. The carbohydrate fragments liberated were partially fractionated, and the disaccharide galactosyl-(1 →3)-N-acetylgalactosaminitol from the linkage region was isolated and characterized.
Technique of Renal Biopsy by Ultrasound Guided Percutaneous Puncture with a Spring Loaded “Gun” (1992)

The study consisted of 89 consecutive patients (mean age = 41.5, range = 16-82, 64 men, 25 women) referred for renal biopsy because of clinical suspicion of renal parenchymal disease. Neither transplant kidneys nor tumour evaluation were included. A biopsy "gun" (Biopty) and 14 (2.0 mm) and 18 (1.2 mm) gauge needles were used with ultrasound guidance. Sixtyseven renal biopsies were guided using a freehand technique 42 using a fixed angle guide attachment. The mean glomerular yield was 9.4 glomeruli. Almost 25% of the 18 gauge needle biopsies (n = 57) had to be repeated and 29.3% of the 14 gauge needle biopsies (n = 75). The yield difference was not statistically significant (Chi-squared = 0.37, p = 0.54). There was no statistically significant difference between the distributions of failure to obtain a significant material for evaluation caused by the biopsy technique used (Chi-squared = 0.08, p = 0.78). When analysing cases of single successful pass the thinner needle produced 6.7 glomeruli (n = 36, SD = 5.08) and the thicker needle 13.8 glomeruli (n = 18, SD = 6.82). No serious complications occurred.
HIV-1 Reverse Transcriptase Inhibitor from <i>Phyllanthus niruri</i> (1992)

An aqueous extract of Phyllanthus niruri (Euphorbiaceae) inhibited human immunodeficiency virus type-1 reverse transcriptase (HIV-1-RT). The inhibitor against HIV-1-RT in this plant was purified by combination of three column chromatographies, Sephadex LH-20, cellulose, and reverse-phase high-performance liquid chromatography. The inhibitor was then identified by nuclear magnetic resonance (NMR) spectra as repandusinic acid A monosodium salt (RA) which was originally isolated from Mallotus repandus. The 50% inhibitory doses (ID50) of RA on HIV-1-RT and DNA polymerase alpha (from HeLa cells) were 0.05 microM and 0.6 microM, respectively, representing approximately a 10-fold more sensitivity of HIV-1-RT compared with DNA polymerase alpha. RA was shown to be a competitive inhibitor with respect to the template-primer while it was a noncompetitive inhibitor with respect to the substrate. RA as low as 10.1 microM inhibited HIV-1-induced cytopathogenicity in MT-4 cells. In addition, 4.5 microM of RA inhibited HIV-1-induced giant cell formation of SUP-T1 approximately 50%. RA (2.5 microM) inhibited up to 90% of HIV-1 specific p24 antigen production in a Clone H9 cell system.
Solid-Phase Epitaxy with X-Ray Irradiation to Grow Dislocation-Free Silicon Films at Low Temperatures (1991)

Amorphous silicon films with a thickness of 300 nm were deposited on silicon wafers. They were irradiated on a water-cooled specimen holder by X-rays using synchrotron radiation. The irradiation effect was investigated by Raman spectroscopy and electron microscopy. It was found that the irradiation at room temperature greatly enhanced homogeneous nucleation in post-annealing at 600°C. X-ray irradiation with a 54-pole wiggler heated the films up to about 500°C, and dislocation-free films were grown epitaxially within 10 min. This irradiation effect on crystal growth is explained by assuming that vacancy-interstitial pairs are formed with X-ray irradiation by Auger processes.
ChemInform Abstract: 1,3‐Dioxanone Derivatives from β‐Hydroxy‐carboxylic Acids and Pivalaldehyde. (1986)

Abstract The dioxanone (III) which is obtained from the compounds (I) and (II) gives an enolate (V) which is stable at low temp. in THF solution and can be alkylated diastereoselectively to the compounds (VI) or (VIII) (mixture of 2 diastereomers).
Dating thermal anomalies in sedimentary basins: the diagenetic history of clay minerals in the Triassic sandstones of the Paris Basin, France (1992)

Abstract Rhaetian (Upper Triassic) sandy horizons were sampled from the Paris Basin from SW to NE, crosscutting the Rhaetian at different depths from outcrop in the NE to 2700 m in the centre of the basin. The smallest day sub-fractions (<0·2 μ m) from the deepest samples consist mainly of illite and chlorite having a K-Ar age of 〜190 Ma. Both minerals probably formed under specific hydrothermal conditions at high temperature, but at a burial depth of only 500 m. This thermal event could represent an echo of the "crustal" breakdown of the Northwestern European craton during the opening of the North Atlantic Ocean. Two other generations of illite-smectite mixed-layers formed in the same Rhaetian horizons at somewhat lower temperatures about 150 and 80 Ma ago. The three generations of clay minerals could be characterized and dated because of combined mineralogical, crystallographical and morphological data supporting the dating attempts.
Tailor made dynamic programming for edge matching (2002)

The authors present an edge pixel matching algorithm based on dynamic programming. Unlike classical dynamic programming methods, where a path is searched for across a graph of the whole space of edge pixels, the approach allows the optimal path to be within a constrained search space, and thus tremendously cutting off the searching time. The knowledge of the camera parameters lends itself to reduce the general problem of image-to-image correspondence problem into a scanline-to-scanline matching problem. That is, once a pair of stereo images is rectified so that the epipolar lines are horizontal scanlines, a pair of corresponding edges in the right and left images should be searched for only within the same horizontal scanlines.
Multi-Modal Audio, Video and Physiological Sensor Learning for Continuous Emotion Prediction (2016)

The automatic determination of emotional state from multimedia content is an inherently challenging problem with a broad range of applications including biomedical diagnostics, multimedia retrieval, and human computer interfaces. The Audio Video Emotion Challenge (AVEC) 2016 provides a well-defined framework for developing and rigorously evaluating innovative approaches for estimating the arousal and valence states of emotion as a function of time. It presents the opportunity for investigating multimodal solutions that include audio, video, and physiological sensor signals. This paper provides an overview of our AVEC Emotion Challenge system, which uses multi-feature learning and fusion across all available modalities. It includes a number of technical contributions, including the development of novel high- and low-level features for modeling emotion in the audio, video, and physiological channels. Low-level features include modeling arousal in audio with minimal prosodic-based descriptors. High-level features are derived from supervised and unsupervised machine learning approaches based on sparse coding and deep learning. Finally, a state space estimation approach is applied for score fusion that demonstrates the importance of exploiting the time-series nature of the arousal and valence states. The resulting system outperforms the baseline systems [10] on the test evaluation set with an achieved Concordant Correlation Coefficient (CCC) for arousal of 0.770 vs 0.702 (baseline) and for valence of 0.687 vs 0.638. Future work will focus on exploiting the time-varying nature of individual channels in the multi-modal framework.
Efficacy of Isotonic Nasal Wash (Seawater) in the Treatment and Prevention of Rhinitis in Children (2008)

Children in the saline group showed faster resolution of some nasal symptoms during acute illness and less frequent reappearance of rhinitis subsequently.
S100B in serum and saliva: a valid invasive or non-invasive biomarker in obstructive sleep apnea? (2016)

Serum S100B allows us to discriminate healthy subjects from patients with OSA. However, it does not live up to its promise as a valid invasive predictor of OSA, since it does not correlate with the severity of the disease. Also, S100B in saliva is not suitable for use as a non-invasive biomarker to detect hypoxia-induced cerebrovascular stress in OSA. This finding prevents an S100B saliva-based assessment of risk or possible extent of structural brain damage, ruling out the possibility of non-invasive home monitoring of compliance and therapeutic efficacy in cases of OSA on treatment.
Geotechnical Design of a Deep Slot Excavation for the Waihi Gold Mine Crusher (2003)

A slot of up to 20 m depth was excavated at Waihi Gold Mine as part of an extension to the open pit mining operations. The slot was excavated to house a Stamler crusher and a jaw crusher that would break up ore from the pit for conveying to the extraction plant by conveyor. The subsurface location minimises operational noise. Excavation support was designed incorporating ad hoc inspections of each wall face immediately after each lift was removed. A succinct case history of the work is presented.
Designing computer systems with MEMS-based storage (2000)

For decades the RAM-to-disk memory hierarchy gap has plagued computer architects. An exciting new storage technology based on microelectromechanical systems (MEMS) is poised to fill a large portion of this performance gap, significantly reduce system power consumption, and enable many new applications. This paper explores the system-level implications of integrating MEMS-based storage into the memory hierarchy. Results show that standalone MEMS-based storage reduces I/O stall times by 4--74X over disks and improves overall application runtimes by 1.9--4.4X. When used as on-board caches for disks, MEMS-based storage improves I/O response time by up to 3.5X. Further, the energy consumption of MEMS-based storage is 10--54X less than that of state-of-the-art low-power disk drives. The combination of the high-level physical characteristics of MEMS-based stor-age (small footprints, high shock tolerance) and the ability to directly integrate MEMS-based storage with processing leads to such new applications as portable gigabit storage systems and ubiquitous active storage nodes.
Effects of weather variables on thermoregulation of calves during periods of extreme heat (2014)

Effects of environmental conditions on thermoregulation in calves exposed to extreme heat were detected. The positive relationship between nasal submucosal temperature and ambient temperature and THI raised concerns about the efficacy of intranasal administration of temperature-sensitive modified-live virus vaccines during periods of extreme heat. Environmental conditions must be considered when rectal temperature is used as a diagnostic tool for identifying morbid cattle.
A fast analog controller for a unity-power factor AC/DC converter (2002)

This paper presents an analog implementation of a fast controller for a unity-power-factor (UPF) AC/DC converter. Unlike low bandwidth controllers associated with many state-of-the-art UPF converters this fast controller can exercise control action at a rate comparable to the switching frequency rather than the line frequency. In order to accomplish this while maintaining unity power factor, the fast controller employs a ripple-feedback cancellation scheme. In addition to responding faster to disturbances, the controller facilitates the replacement of bulky bus capacitors with smaller, less expensive alternatives.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Effect of Mechanical Boundary Conditions on Phase Diagrams of Epitaxial Ferroelectric Thin Films (1998)

A phenomenological thermodynamic theory of ferroelectric thin films epitaxially grown on cubic substrates is developed using a new form of the thermodynamic potential, which corresponds to the actual mechanical boundary conditions of the problem. For single-domain ${\mathrm{BaTiO}}_{3}$ and ${\mathrm{PbTiO}}_{3}$ films, the ``misfit-temperature'' phase diagrams are constructed. It is found that the 2D clamping of the films, apart from a shift of the temperature of the ferroelectric transition, results in a change of its order. A change of the sequence of the phases and the appearance of phases forbidden in the bulk crystals are predicted.
Robot imitation of human arm via Artificial Neural Network (2014)

In this study, a robot arm that can imitate human arm is designed and presented. The potentiometers are located to the joints of the human arm in order to detect movements of human gestures, and data were collected by this way. The collected data named as “movement of human arm” are classified by the help of Artificial Neural Network (ANN). The robot performs its movements according to the classified movements of the human. Real robot and real data are used in this study. Obtained results show that the learning application of imitating human action via the robot was successfully implemented. With this application, the platforms of robot arm in an industrial environment can be controlled more easily; on the other hand, robotic automation systems which have the capability of making a standard movements of a human can become more resistant to the errors.
Chemical constituents from the endophytic fungus Trichoderma ovalisporum isolated from Panax notoginseng (2010)

Strain PRE-5 was isolated from the root of the herbal plant Panax notoginseng and was identified as Trichoderma ovalisporum based on its sequence at the internal transcribed spacer (ITS) regions. From the extracts of fermentation broth and mycelia of strain PRE-5, five compounds koninginin A (1), (E)-2,3-dihydroxypropyl octadec-9-enoate (2), shikimic acid (3), adenine ribonucleoside (4), and cytosine ribonucleoside (5) were obtained. Their structures were elucidated on the basis of their spectroscopic data. All compounds were assayed for antibacterial activity. Compound 3 showed activity against Staphylococcus aureus, Bacillus cereus, Micrococcus luteus and Escherichia coli.
Optimizing CAR-T Cell Manufacturing Processes during Pivotal Clinical Trials (2019)

Tisagenlecleucel is a CD19-specific chimeric antigen receptor (CAR)-T cell therapy approved for patients aged ≤25 years with relapsed or refractory B cell precursor acute lymphoblastic leukemia (B-ALL) and adults with relapsed or refractory diffuse large B cell lymphoma (DLBCL). The initial tisagenlecleucel manufacturing process technology was developed at an academic center and was subsequently transferred, optimized, validated, and scaled out to supply large global trials before commercialization. Tisagenlecleucel manufactured in two centralized facilities has been successfully used in global multicenter trials for B-ALL and DLBCL (>50 clinical centers in 12 countries). In this paper, we describe some of the continuous process improvements made to tisagenlecleucel manufacturing over time to meet global demand while maintaining and improving product quality. During early tisagenlecleucel clinical trials, process enhancements were made to address logistical challenges related to manufacturing for multicenter trials and to accommodate the variability observed in patient starting cellular material. These enhancements resulted in improvements in manufacturing capacity, process robustness, manufacturing success rates, and product quality, and reductions in throughput time. In summary, through continuous evaluation and improvements based on experience during global trials, a consistent and robust commercial manufacturing process for tisagenlecleucel has been developed, leading to improvements in manufacturing success when compared to the initial processes.
Drug Therapy in the Heart Transplant Recipient (2004)

art I of this series describes the mechanisms and types of rejection and the intravenous immunosuppressive drugs commonly used for induction or antirejection therapy.In this article, we review the commonly used oral immunosuppressive drugs.Intravenous corticosteroid methylprednisolone is included in the discussion of corticosteroids.Table 1 gives trade names, pharmacology, necessary adjustments for renal or hepatic dysfunction, and dosing and general monitoring guidelines for drugs described in this section.Table 2 lists the major adverse effects of immunosuppressive drugs described in Parts I and II of this review and provides an estimate of their relative frequency. Corticosteroids (Steroids)Steroids, among the first immunosuppressive agents used in clinical transplantation, have remained an important component of induction, maintenance, and rejection regimens.
The acute phase response does not fully predict the presence of insulin resistance and dyslipidemia in inflammatory arthritis. (2002)

Insulin resistance and dyslipidemia were highly prevalent in patients with inflammatory arthritis. The acute phase response and excess weight could fully explain the insulin resistance but only partially explain the dyslipidemia. These findings have important implications for the management of inflammatory arthritis.
The mechanism of action of chlorhexidine (1988)

Controversy exists concerning the mode of action of chlorhexidine in plaque inhibition. This study attempted to determine whether an oral reservoir of chlorhexidine was necessary for plaque inhibition. Plaque growth on enamel under the influence of topically applied or rinsed chlorhexidine was closely monitored by clinical scoring, bacterial culturing and scanning electron microscopy. Thus, 3 subjects wore removable acrylic appliances containing enamel inserts. In the first regimen, inserts on one side of the appliances were exposed to 0.2% chlorhexidine and on the other, water for 1 min twice a day for 14 days. In the second regimen, subjects rinsed with 0.2% chlorhexidine for 1 min twice a day for 14 days with the appliances in situ. Results demonstrated that plaque growth assessed by the 3 study methods was very small on chlorhexidine-treated inserts by comparison with water-treated specimens. Importantly, inserts treated with chlorhexidine topically or by rinsing could not be distinguished by any method of evaluation. It is concluded that chlorhexidine achieves plaque inhibition as a result of an immediate bactericidal action during the time of application and a prolonged bacteriostatic action as a result of adsorption to the pellicle coated enamel surface. Consistent with other clinical studies, it is apparent that a progressively desorbing oral reservoir of antiseptic is not the mechanism by which chlorhexidine achieves plaque inhibition on teeth.
Remote applications of electric potential sensors in electrically unshielded environments (2010)

The electric potential sensor is a novel, ultra high impedance sensor, previously developed at the University of Sussex. These sensors have been applied to a range of applications, including electrophysiology, non destructive testing of composite materials and novel nuclear magnetic resonance NMR probes. Some of these measurements can be made in a strongly coupled (=100pF) mode, where the coupling capacitance is reasonably large and well dened, and ambient noise is therefore less problematic. However for many applications, there exists a requirement for this coupling to be much weaker. This weak and poorly dened coupling creates substantial problems with ambient noise often causing sensors to saturate and become unusable. In the past, therefore, these measurements have all been made inside electrically screened rooms and enclosures. The work discussed in this thesis explores the possibility of operating these sensors outside of electrically screened environments. A number of techniques for resilience against noise are explored and experiments to fully analyse and characterise the performance of the sensors are discussed. As a result of this work, further results are then shown for a number of experiments carried out in a busy lab environment, in the presence of noise sources, and with little or minimal screening used. In this case, data is shown for the collection of remote cardiac and respiratory data, imaging of the spatial distribution of charge on insulating materials, detecting electric eld disturbances for movement sensing and early results for a microscopic XY scanning application.
Kinetic evidence for a common transporter for glycylsarcosine and phenylalanylprolylalanine in renal brush-border membrane vesicles. (1990)

We investigated the interaction between glycylsarcosine (Gly-Sar), a neutral dipeptide, and phenylalanylprolylalanine (Phe-Pro-Ala), a neutral tripeptide, for transport into renal brush-border membrane vesicles isolated from Japanese F344 rats. This rat strain is genetically deficient in dipeptidylpeptidase IV. Owing to the absence of this enzyme, Phe-Pro-Ala was found to be completely resistant to hydrolysis by the brush-border membranes, and this enabled us to study the uptake of the intact tripeptide without interference by hydrolysis. Gly-Sar was also resistant to hydrolysis by these membrane preparations. Transport of Gly-Sar as well as that of Phe-Pro-Ala in these vesicles was driven by an inwardly directed H+ gradient. Gly-Sar transport was blocked completely by increasing concentrations of Phe-Pro-Ala and vice versa. Gly-Sar inhibited Phe-Pro-Ala transport competitively; and similarly, Phe-Pro-Ala inhibited Gly-Sar transport competitively. The dissociation constant (Kt) for Gly-Sar transport (94 +/- 5 microM) was very similar to the inhibition constant (Ki) for Gly-Sar to inhibit Phe-Pro-Ala transport (107 +/- 13 microM). The Kt for Phe-Pro-Ala transport (36 +/- 3 microM) was equal to the Ki for Phe-Pro-Ala to inhibit Gly-Sar transport (36 +/- 6 microM). Furthermore, linear correlation was exhibited by various neutral di- and tripeptides, which were also resistant to hydrolysis, in their abilities to inhibit the transport of Gly-Sar and that of Phe-Pro-Ala. These results strongly suggest that a common carrier system participates in the transport of neutral di- and tripeptides in renal brush-border membrane vesicles.