gebhart/patrepeval huggingface dataset:
Possible strategy to use differential mobility spectrometry in real time applications (2019)

Differential Mobility Spectrometry (DMS), also called as FAIMS is a variation of atmospheric pressure ion mobility measurement techniques and is capable of providing information about the electric field - mobility dependence of ions. In this method, a combined electric field is used. This field consists of asymmetric oscillating electric field of high intensity and low static field component. Analytical information in DMS is 2-dimensional dependence of ionic current on oscillating field amplitude and the value of static field intensity. The measurement of DMS signal for whole ranges of both variables is time consuming and also generates lot of data. It is a disadvantage of DMS method, which limits the use of this otherwise powerful technology in real time applications that require a response time of few seconds. This paper presents a way to limit measurement time by heuristic knowledge of the properties of the data space and another method based on the concept of Shannon Entropy to find operating parameters satisfying both separation and signal to noise ratio requirements.
Functional significance of VEGFR‐2 on ovarian cancer cells (2008)

Vascular endothelial growth factor receptor (VEGFR) has recently been discovered on ovarian cancer cells, but its functional significance is unknown and is the focus of this study. By protein analysis, A2780-par and HeyA8 ovarian cancer cell lines expressed VEGFR-1 and HeyA8 A2774, and SKOV3ip1 expressed VEGFR-2. By in situ hybridization (ISH), 85% of human ovarian cancer specimens showed moderate to high VEGFR-2 expression, whereas only 15% showed moderate to high VEGFR-1 expression. By immunofluorescence, little or no VEGFR-2 was detected in normal ovarian surface epithelial cells, whereas expression was detected in 75% of invasive ovarian cancer specimens. To differentiate between the effects of tumor versus host expression of VEGFR, nude mice were injected with SKOV3ip1 cells and treated with either human VEGFR-2 specific antibody (1121B), murine VEGFR-2 specific antibody (DC101) or the combination. Treatment with 1121B reduced SKOV3ip1 cell migration by 68% (p < 0.01) and invasion by 72% (p < 0.01), but exposure to VEGFR-1 antibody had no effect. Treatment with 1121B effectively blocked VEGF-induced phosphorylation of p130Cas. In vivo treatment with either DC101 or 1121B significantly reduced tumor growth alone and in combination in the SKOV3ip1 and A2774 models. Decreased tumor burden after treatment with DC101 or 1121B correlated with increased tumor cell apoptosis, decreased proliferative index, and decreased microvessel density. These effects were significantly greater in the combination group (p < 0.001). We show functionally active VEGFR-2 is present on most ovarian cancer cells. The observed anti-tumor activity of VEGF-targeted therapies may be mediated by both anti-angiogenic and direct anti-tumor effects.
An adaptive hybrid ARQ scheme using shortened codes (2002)

In this paper we propose a sub-block retransmission scheme for ARQ and hybrid ARQ schemes. When the channel is quiet the sub-block retransmission scheme behaves like a conventional ARQ or hybrid ARQ scheme. As the channel becomes noisy, the data block is divided into small sub-blocks for transmission. Each sub-block is encoded for error control by an appropriate shortened code and the code length of the shortened code is adaptive to the corresponding channel BER. The received block is checked for errors sub-block by sub-block. The proposed sub-block retransmission scheme provides improved throughput over conventional ARQ schemes by retransmitting only the naked sub-blocks in the occurrence of errors. An example of transferring ATM cells is considered for simulation.
Synthesis of Poly(propylene-<i>r</i><i>an</i>-1,3-butadiene) and Its Metathesis Degradation with Ethylene (2003)

ADVERTISEMENT RETURN TO ISSUECommunication to the...Communication to the EditorNEXTSynthesis of Poly(propylene-ran-1,3-butadiene) and Its Metathesis Degradation with EthyleneTakeshi Ishihara and Takeshi ShionoView Author Information Japan Chemical Innovation Institute, AIST Tsukuba, Central 5-8, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan, and Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuda 4259, Midori-ku, Yokohama 226-8503, Japan Cite this: Macromolecules 2003, 36, 26, 9675–9677Publication Date (Web):November 21, 2003Publication History Received7 July 2003Revised5 November 2003Published online21 November 2003Published inissue 1 December 2003https://pubs.acs.org/doi/10.1021/ma0349480https://doi.org/10.1021/ma0349480rapid-communicationACS PublicationsCopyright © 2003 American Chemical SocietyRequest reuse permissionsArticle Views769Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Alkyls,Copolymerization,Copolymers,Polymer chains,Thermoresponsive polymers Get e-Alerts
Protective Efficacy of Hybridoma Type-Specific Antibody Against Experimental Infection with Group-B Streptococcus (1984)

Murine monoclonal antibodies to group-B Streptococcus type III were developed by fusion of splenic lymphocytes from immunized BALB/c mice with the mouse-myeloma cell line SP 2/0. The four type III-specific antibodies, which were of the IgM class, protected neonatal rats against intraperitoneal infection with homologous-type group-B streptococci; survival rates were 95%-100% for protected rats but only 17% for unprotected rats. One antibody preparation offered excellent protection against any of five type-III strains employed. Monoclonal antibody provided protection when administered 4, 8, or 12 hr after infection, although delayed administration was less efficacious against more virulent strains. Monoclonal IgM also protected against intranasal inoculation of bacteria. These results indicate the potential therapeutic efficacy of monoclonal antibody in neonatal group-B streptococcal disease, but further laboratory investigations must precede clinical investigation of monoclonal or polyclonal antibody therapy in humans.
Monitoring an oil-sands reservoir in northwest Alberta using time-lapse 3D seismic and 3D P-SV converted-wave data (2008)

Time-lapse 3D seismic monitoring was conducted in the Japan Canada Oil Sands Limited (JACOS) Hangingstone steam-assisted-gravity-drainage (SAGD) operation area in Alberta, Canada, to delineate steam-affected areas. The time-lapse surveys, acquired in February 2002 and March 2006, show distinct response changes around the SAGD well pairs. In addition, 3D P-SV converted-wave processing and analysis were applied on the second 3D data set (recorded with three-component digital sensors) for a reservoir characterization study.
Self-organization of domain structures by DNA-loop-extruding enzymes (2012)

The long chromosomal DNAs of cells are organized into loop domains much larger in size than individual DNA-binding enzymes, presenting the question of how formation of such structures is controlled. We present a model for generation of defined chromosomal loops, based on molecular machines consisting of two coupled and oppositely directed motile elements which extrude loops from the double helix along which they translocate, while excluding one another sterically. If these machines do not dissociate from DNA (infinite processivity), a disordered, exponential steady-state distribution of small loops is obtained. However, if dissociation and rebinding of the machines occurs at a finite rate (finite processivity), the steady state qualitatively changes to a highly ordered 'stacked' configuration with suppressed fluctuations, organizing a single large, stable loop domain anchored by several machines. The size of the resulting domain can be simply regulated by boundary elements, which halt the progress of the extrusion machines. Possible realizations of these types of molecular machines are discussed, with a major focus on structural maintenance of chromosome complexes and also with discussion of type I restriction enzymes. This mechanism could explain the geometrically uniform folding of eukaryote mitotic chromosomes, through extrusion of pre-programmed loops and concomitant chromosome compaction.
Safety evaluation of chemicals: The regulatory framework (1986)

Abstract Major industrial countries have relatively recent new laws regulating the manufacture, distribution and use of industrial chemical products. The resultant regulations in the United States (under TSCA), European countries, Japan, and Australia, with emphasis on the testing requirements, are summarized.
A Distributed Particle Swarm Optimization Algorithm for Swarm Robotic Applications (2006)

We have derived a version of the particle swarm optimization algorithm that is suitable for a swarm consisting of a large number of small, mobile robots. The algorithm, called the distributed PSO (dPSO), is for "search" type operations and allows each robot to calculate its new position based on its present position and present measurement. It eliminates the needs for a central agent to coordinate the movements of the robots and has limited inter-robot communications requirements. Simulation results show that the dPSO is very good at finding a target location within a search space and is easily scaleable to large numbers of robots.
Configuration Energies of the Main Group Elements (2000)

Configuration energies (CEs), formerly called spectroscopic electronegativities, are an attempt to quantum mechanically define, and extend, the important chemical concept of electronegativity. In a previous paper (J. Am. Chem. Soc. 1989, 111, 9003) we reported high-resolution experimental values obtained from the National Institutes of Science and Technology spectroscopic energy level tables using the formula CE = (nεs + mεp)/(n + m). where n and m are the number of s and p electrons and εs and εp are their multiplet averaged one-electron energies, for the 34 s and p-block atoms H→Xe. This CE definition is a direct extension of N. Bohr's introduction of electron configurations to quantum mechanically rationalize the periodic table (hence its designation as configuration energy). Here we give experimental numbers for the remaining 8 sixth row representative atoms plus Zn, Cd, and Hg. In addition, we have carried out high accuracy numerical Dirac−Hartree−Fock solutions for all 45 atoms. Results from these calculations closely parallel the experimental values and enable us to estimate some of the atomic multiplet levels for which no experimental data exist. CE leads to numbers which are interpretable as an “electron attracting power” in the same manner as the traditional scales of Pauling and Allred & Rochow. They are also strongly correlated with atomic energy level spacings, therefore providing an additional interpretability compatible with energy level data and the molecular orbital diagrams that dominate much of contemporary chemistry. Likewise, CEs are able to rationalize the origin of the metalloid band (diagonal line separating metals from nonmetals) in the periodic table and the new determination of sixth row CEs permit designation of bismuth and polonium as metalloids, clarifying their previous uncertain classification between metal and metalloid.
Subjectivity (1996)

1 Professor of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, Connecticut 06519.
Conserveermiddelen on-line (2004)

Antimicrobials Online is een Engelstalige database die wetenschappelijke informatie over natuurlijke conserveermiddelen via internet beschikbaar stelt aan de levensmiddelenindustrie. Het project is uitgevoerd door Wageningen UR-Agrotechnology & Food Innovations. Er volgt uitbreiding met traditionele voedingsmiddelen
Occupational risks for colon cancer in Sweden. (1994)

Using the Cancer-Environment Registry of Sweden, which links census information (1960) with cancer incidence data (1961 to 1979), we conducted a systematic, population-based assessment of colon cancer incidence among cohorts defined by industry and occupation for all employed persons in Sweden. Small but statistically significant excesses of colon cancer were observed among white-collar occupations, including administrators, professionals, and clerical and sales workers, whereas a reduction in incidence was found among workers in agricultural and related jobs, such as farmers, fishermen, and hunters. Analysis by subsite within the colon revealed little difference in results. The observed risk patterns are consistent with previous reports on colon cancer risk and occupational physical activity levels, ie, elevated risk among sedentary white-collar workers and reduced risk among agricultural workers. Few craftsman and production processing jobs were linked to colon cancer, although statistically significant excesses were observed among shoe and leather workers, metal smiths, and foundry workers in the metal manufacturing industry. The findings indicate that occupation in general is likely to play a relatively small role in colon cancer etiology, with perhaps its major contribution an indirect one via physical activity.
Effects of pioglitazone and metformin on plasma adiponectin in newly detected type 2 diabetes mellitus (2006)

Pioglitazone therapy appears to be better in achieving glycaemic control and increasing plasma adiponectin and insulin sensitivity in newly detected type 2 diabetics.
Economic Evaluation of Field Bindweed (<i>Convolvulus arvensis</i>) Control in a Winter Wheat-Fallow Rotation (1996)

Field bindweed infests millions of hectares in the Great Plains greatly reducing productivity and value of land. The standard practice for field bindweed control is sweep tillage at 3 wk intervals combined with one or two annual 2,4-D) applications during the 14 mo fallow period in a winter wheat-fallow crop rotation. This was compared to tillage and 2,4-D in conjunction with dicamba or a mixture of picloram+2,4-D applied once during the first October of the first 14 mo fallow period. Also, three no-tillage systems were included using glyphosate+2,4-D at monthly intervals. Two of the treatments were supplemented with dicamba, or picloram+2,4-D as in the sweep tillage system. All treatments controlled field bindweed in two fallow periods and two winter wheat crops, and increased winter wheat yields to about twice the control. Sweep tillage at 3 wk intervals combined with 2,4-D resulted in $36 ha −1 profit for an owner-operator compared to $15 ha −1 loss with no herbicide or tillage treatment. On average no-tillage lost $35 ha −1 . Other treatments, although controlling field bindweed, lost from 35 to $186 ha −1 . To determine if long-term benefit after control was achieved, average yields for the area were used to calculate profits using normal farming practices. Profits were 136, 78, and $-50 ha −1 , respectively, for sweep tillage and 2,4-D, no-tillage, and the untreated check. In a standard 33:67 owner-tenant rental, profits to the owner for the control period were 90, −33, and $43 ha −1 , respectively for tillage and 2,4-D, no-tillage, and untreated check. The tenant lost from $24 to 69 ha −1 for the three systems indicating owners must modify rental agreements during a field bindweed control program.
A bird's beak reduction technique for LOCOS in VLSI Fabrication (1986)

The local oxidation of silicon (LOCOS) enhancement technique using a thin nitridized pad oxide formed by thermally nitridizing a thin thermal oxide in ammonia gas ambient has been developed for fabricating a defect-free near-zero bird's beak field isolation structure. By directly measuring the bird's beak length from the SEM cross-sectional view of the enhanced LOCOS structure, the process regime for reducing the bird's beak length down to 0.1 µm with a field oxide thickness of 8000 Å has been exploited.
Time-interleaved oversampling convertors (1993)

A new architecture is proposed which exploits the time-interleaving concept to increase the oversampling ratio in delta-sigma modulators. It is shown that the effective oversampling ratio is increased by a factor M through the use of M interconnected modulators. Although a high speed sample-and-hold circuit is still required for an analogue-to-digital convertor, speed constraints are significantly reduced for the majority of analogue parts such as loop filters, A/D and D/A blocks.
Estimating risks of common complex diseases across genetic and environmental factors: the example of Crohn disease (2007)

High absolute risks of CD disease can be obtained by incorporating information on smoking, family history and CARD15 mutations. Behaviour modification through smoking cessation may reduce CD risk in these people.
Dataport and NILMTK: A building data set designed for non-intrusive load monitoring (2015)

Non-intrusive load monitoring (NILM), or energy disaggregation, is the process of using signal processing and machine learning to separate the energy consumption of a building into individual appliances. In recent years, a number of data sets have been released in order to evaluate such approaches, which contain both building-level and appliance-level energy data. However, these data sets typically cover less than 10 households due to the financial cost of such deployments, and are not released in a format which allows the data sets to be easily used by energy disaggregation researchers. To this end, the Dataport database was created by Pecan Street Inc, which contains 1 minute circuit-level and building-level electricity data from 722 households. Furthermore, the non-intrusive load monitoring toolkit (NILMTK) was released in 2014, which provides software infrastructure to support energy disaggregation research, such as data set parsers, benchmark disaggregation algorithms and accuracy metrics. This paper describes the release of a subset of the Dataport database in NILMTK format, containing one month of electricity data from 669 households. Through the release of this Dataport data in NILMTK format, we pose a challenge to the signal processing community to produce energy disaggregation algorithms which are both accurate and scalable.
GaAs Dynamic Digital IC's for Applications Up to 10 GHz (1982)

To evaluate the potentiality of GaAs MESFET's as transmitting gates, dynamic T flip-flops have been fabricated using a self-aligned planar process. The maximum operating frequency is 10.2 GHz which is the best speed performance ever reported for a digital circuit. The performance of the transmitting gates within the circuit are discussed in details. Speed improvement and topological simplification of fully static LSI subsystems are investigated.
A Blockchain-Based Peer-to-Peer Trading Scheme Coupling Energy and Carbon Markets (2019)

Climate change enforces the integration of distributed renewable energy sources and development of carbon price scheme. Whilst the energy is traded among distributed prosumers, the carbon responsibilities and corresponding allowances trading need to be transferred from large-scale energy suppliers to prosumers. During this transformation, the issues of energy imbalance, carbon reduction imbalance, and residential privacy leakage in centralised trading market present serious challenges. In this paper, we propose a fully decentralised blockchain-based peer-to-peer trading scheme coupling energy and carbon markets. We implement pay-to-public-key-hash with multiple signatures as a transaction standard to realise a more secure transaction and reduced storage burden of senders. A script is hashed during the wallet address generation for each new transaction to protect residential privacy. A novel carbon accounting method and corresponding incentive mechanism for carbon reduction are designed to evaluate emission behaviours of distributed prosumers. Case studies demonstrate that the proposed scheme leads a reduced costs and carbon emissions compared to centralised trading systems and existing blockchain-based trading schemes.
Non-Markovian effects in strong-field pair creation (1999)

We analyze a quantum kinetic equation describing both boson and fermion pair production and explore analytically and numerically the solution of the non-Markovian kinetic equation. In the low density limit of the kinetic equation we find an analytical solution for the single particle distribution function of bosons and fermions. The numerical investigation for a homogeneous, constant electric field shows an enhancement (bosons) or a suppression (fermions) of the pair creation rate according to the symmetry character of the produced particles. For strong fields non-Markovian effects are important while they disappear for weak fields. Hence it is sufficient to apply the low density limit for weak fields but necessary to take into account memory effects for strong fields.
Bloom Syndrome (1993)

Spontaneous mutations in human somatic cells occur far more often than normal in individuals with Bloom syndrome. The basis for understanding these mutations and their developmental consequences emerges from examination of BS at the molecular, cellular, and clinical levels. The major clinical feature of BS, proportional dwarfism, as well as its major clinical complication, an exceptionally early emergence of neoplasia of the types and sites that affect the general population, are attributable to the excessive occurrence of mutations in somatic cells. Here, the following aspects of BS are discussed: (i) the BS phenotype; (ii) neoplasia in BS, including the means--the Bloom's Syndrome Registry--by which the significant risk for diverse sites and types of cancer in these patients was revealed; (iii) the biological basis for the cancer proneness of BS; and, finally, (iv) the significance for both basic human biology and clinical medicine of BS as the prototype of somatic mutational disease.
Reversibility of Platelet Thrombosis In Vivo (1996)

Reversibility in vivo of acute platelet thrombosis in response to specific anticoagulants is analyzed with thrombi that develop in segments (1 cm) of porcine carotid arteries externally crushed with a hemostat. Most thrombi fill the lumens of the injured segments (ca. 1 cm x 3 mm, 1 x w) within 30 min and comprise masses of platelets interpenetrated with neutrophil-lined seepage channels of blood. Continuous quantitative assay of thrombus mass is provided by a gamma detector placed over the injured segments to collect counts from 111In-labeled platelets. Thrombi established 30 min after injury, otherwise stable for 6 h, clear during 30-60 min of continuous infusion of either hirudin, tick anticoagulant or activated porcine protein C, or intermittent activation of endogenous protein C with a latent thrombin reagent. Anticoagulant dose-dependence of thrombus clearance is established for hirudin between 0.01 and 1.0 mg/kg/min. Thrombi become progressively refractory to hirudin between 0.5 and 6 h after injury. Neither heparin no low-molecular-weight heparin in full (clinical) anticoagulant doses yield significant dethrombosis. It is concluded that, within time limits, controlled thrombin generation in platelet thrombi maintains platelet cohesion without catalyzing irreversible platelet aggregation or clotting of fibrinogen.