gebhart/patrepeval huggingface dataset:
Sensitivity of Epstein‐Barr virus‐induced B cell tumor to apoptosis mediated by anti‐CD95/Apo‐1/fas antibody (1997)

Epstein-Barr virus (EBV) can induce uncontrolled B lymphocyte proliferation leading to fatal lymphoma in immunocompromised patients. The sensitivity to apoptosis of B lymphoid cell lines (LCL) derived from EBV-induced lymphoproliferative disorders was investigated. In vitro and in vivo, these B LCL strongly express CD95/Apo-1/fas antigen and undergo apoptosis upon stimulation with anti-Apo-1 monoclonal antibody. When inoculated into severe-combined immunodeficient (scid) mice, human B cells lines developed into rapidly growing tumors. Administration of an agonistic anti-Apo-1 antibody significantly delayed tumor progression. Relapses were frequent, but were not caused by selection of resistant B cells, since B cells from relapsing tumors underwent apoptosis on re-exposure. Induction of apoptosis by an anti-C95/Apo-1/fas-specific antibody could be applied for therapy of EBV-induced B cell tumors and contribute to our understanding of the mechanisms of T cell-mediated elimination of EBV lymphomas in immunodeficient patients.
An immunological window on leukaemia. (1989)

Immunologie des leucemies humaines, en particulier de la leucemie lymphoblastique (ALL); etiologie de l'ALL: role des genes dont les produits sont impliques dans la proliferation cellulaire et/ou la differenciation
Robust video hashing based on radial projections of key frames (2005)

Robust signal hashing defines a feature vector that characterizes the signal, independently of "nonsignificant" distortions of its content. When dealing with images, the considered distortions are typically due to compression or small geometrical manipulations. In other words, robustness means that images that are visually indistinguishable should produce equal or similar hash values. To discriminate image contents, a hash function should produce distinct outputs for different images. Our paper first proposes a robust hashing algorithm for still images. It is based on radial projection of the image pixels and is denoted the Radial hASHing (RASH) algorithm. Experimental results provided on the USC-SIPI dataset reveal that the proposed RASH feature vector is more robust and provides much stronger discrimination than a conventional histogram-based feature vector. The RASH vector appears to be a good candidate to build indexing algorithms, copy-detection systems, or content-based authentication mechanisms. To take benefit from the RASH vector capabilities, video content is summarized into key frames, each of them characterizing a video shot and described by its RASH vector. The resulting video hashing system works in real time and supports most distortions due to common spatial and temporal video distortions.
Connected Cars on Wireless Roads: Making it a Reality (2006)

The rapid growth of wireless data capabilities in the home and office environment has naturally led to the extension of these capabilities to more mobile environments. Here, the potential exists to utilize this broadband connectivity to enhance the effectiveness of currently deployed vehicle and infrastructure based safety and convenience capabilities. This talk will explore some of the unique requirements imposed by the combination of mobility and safety requirements in this broadband environment which will differentiate the solutions in this space from those found in the commercial home and office wireless deployments.
Surface-Controlled Metal Oxide Resistive Memory (2015)

To explore the surface effect on resistive random-access memory (ReRAM), the impact of surface roughness on the characteristics of ZnO ReRAM was studied. The thickness-independent resistance and the higher switching probability of ZnO ReRAM with rough surfaces indicate the importance of surface oxygen chemisorption on the switching process. Furthermore, the improvements in switching probability, switching voltage, and resistance distribution observed for ReRAM with rough surfaces can be attributed to the stable oxygen adatoms under various ambience conditions. The findings validate the surface-controlled stability and the uniformity of ReRAM and can serve as the guideline for developing practical device applications.
Genes involved in tumor invasion and metastasis are differentially modulated by estradiol and progestin in human breast‐cancer cells (1992)

Invasion of basement membranes by cancer cells is a critical step in metastasis, which requires the coordinated expression of specific genes such as laminin receptors and metalloproteinases. Estradiol and progesterone modulate the clinical progression of steroid-sensitive breast cancers; however, little is known about the molecular regulation of the invasive phenotype by these hormones. We therefore examined the effects of 10 nM estradiol and/or 10 nM progestin R5020 on the expression of 2 non-integrin laminin binding proteins, the 67-kDa laminin receptor (67LR) and HLBP31 as well as the 72-kDa type-IV collagenase (MMP-2) and its inhibitor, TIMP-2, in steroid-receptor-positive (T47D and MCF-7) and -negative (MDA-MB 231) human breast-cancer cells. The relative steady-state level of 67LR mRNA was increased 2- to 3-fold by estradiol in both MCF-7 (p < 0.001) and T47D (p < 0.001) cells, also by R5020, alone or in combination with estradiol, in T47D cells (p < 0.001) and to a much less extent in MCF-7 cells. HLBP31 mRNA and protein levels were increased 2- to 3-fold (p < 0.001) by R5020 alone or in combination with estradiol, but not by estradiol alone. None of the steroid treatments affected the expression or activity of MMP-2. Interestingly, however, TIMP-2 mRNA levels and protein expression in MCF-7 and T47D cells were 50% down-regulated (p < 0.001) by treatment with R5020 or R5020 plus estradiol, but not by treatment with estradiol alone. None of these genes were modulated in steroid-independent MDA-MB231 cells. The data suggest that estradiol and progesterone might act as coordinators regulating specific genes in the steroid-sensitive breast-cancer cell, leading to the acquisition of the metastatic phenotype.
Use of aluminum trihydrate filler to improve the strength properties of cellulosic paper exposed to high temperature treatment (2011)

Cellulosic paper is thermolabile and its strength properties tend to decrease under high temperature conditions. In this work, the effects of aluminum trihydrate filler on the tensile and burst strength of paper prepared from bleached wood pulps were investigated. The use of aluminum trihydrate maintained the tensile and burst strength of paper sheet dried at 200 °C for 4 hours. Thermogravimetric analysis and differential scanning calorimetry gave the evidence that the maintainance of strength after drying associated with the use of aluminum trihydrate filler is possibly due to the increase in degradation temperature and heat absorption of cellulosic paper. The results regarding Fourier Transform Infrared spectroscopy, and the () and crystallinity index of fibers indicated the alleviated degradation of fibers when aluminum trihydrate was incorporated into the paper matrix.
Analysis of twiddle factor memory complexity of radix-2<sup>i</sup> pipelined FFTs (2009)

In this work, we analyze different approaches to store the coefficient twiddle factors for different stages of pipelined Fast Fourier Transforms (FFTs). The analysis is based on complexity comparisons of different algorithms when implemented on Field-Programmable Gate Arrays (FPGAs) and ASIC for different radix-2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">i</sup> algorithms. The objective of this work is to investigate the best possible combination for storing the coefficient twiddle factor for each stage of the pipelined FFT.
Comparison of Filter Bank Based Multicarrier Systems with OFDM (2006)

Multicarrier systems are favored for contemporary and future, both stationary and mobile, communication systems. They promise a high bandwidth efficiency and at the same time the capability to cope with frequency selective (radio) channels. Unfortunately, the peak-to-average power ratio (PAPR) is increased at the transmitter of multicarrier systems compared to single carrier systems. Filter bank based multi-carrier systems, i. e. transmultiplexer filter banks, provide a much better spectral shaping of the subcarriers than orthogonal frequency division multiplexing (OFDM). This leads to several advantages against OFDM systems, which are highlighted in this contribution. Particularly, the PAPR performance of filter bank based multicarriers systems and OFDM are compared
SARS-CoV-2 Genome Sequencing Methods Differ in Their Abilities To Detect Variants from Low-Viral-Load Samples (2021)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomic surveillance has been vital in understanding the spread of coronavirus disease 2019 (COVID-19), the emergence of viral escape mutants, and variants of concern. However, low viral loads in clinical specimens affect variant calling for phylogenetic analyses and detection of low-frequency variants, important in uncovering infection transmission chains. We systematically evaluated three widely adopted SARS-CoV-2 whole-genome sequencing methods for their sensitivity, specificity, and ability to reliably detect low-frequency variants. Our analyses reveal that the ARTIC v3 protocol consistently displays high sensitivity for generating complete genomes at low viral loads compared with the probe-based Illumina Respiratory Viral Oligo panel and a pooled long-amplicon method. We show substantial variability in the number and location of low-frequency variants detected using the three methods, highlighting the importance of selecting appropriate methods to obtain high-quality sequence data from low-viral-load samples for public health and genomic surveillance purposes.
Structural Characterization of a Pentadienyl Radical Intermediate Formed during Catalysis by Prostaglandin H Synthase-2 (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTStructural Characterization of a Pentadienyl Radical Intermediate Formed during Catalysis by Prostaglandin H Synthase-2Sheng Peng, Nicole M. Okeley, Ah-Lim Tsai, Gang Wu, Richard J. Kulmacz, and Wilfred A. van der DonkView Author Information Department of Chemistry University of Illinois at Urbana-Champaign 600 South Mathews Avenue, Urbana, Illinois 61801 Division of Hematology, Internal Medicine University of Texas Medical School at Houston 6431 Fannin, Houston, Texas 77030 Cite this: J. Am. Chem. Soc. 2001, 123, 15, 3609–3610Publication Date (Web):March 23, 2001Publication History Received29 January 2001Published online23 March 2001Published inissue 1 April 2001https://pubs.acs.org/doi/10.1021/ja015599xhttps://doi.org/10.1021/ja015599xrapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views478Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Cations,Electron paramagnetic resonance spectroscopy,Lipids,Peptides and proteins,Quantum mechanics Get e-Alerts
The kinetic depth effect. (1953)

The problem of how three-dimensional form is perceived in spite of the fact that pertinent stimulation consists only in two-dimensional retinal images has been only partly solved. Much is known about the impressive effectiveness of binocular disparity. However, the excellent perception of threedimensional form in monocular vision has remained essentially unexplained. It has been proposed that some patterns of stimulation on the retina give rise to three-dimensional experiences, because visual processes differ in the spontaneous organization that results from certain properties of the retinal pattern. Rules of organization are supposed to exist according to which most retinal projections of three-dimensional forms happen to produce three-dimensional percepts and most retinal images of flat forms lead to flat forms in experience also. This view has been held mainly by gestalt psychologists. Another approach to this problem maintains that the projected stimulus patterns are interpreted on the basis of previous experience, either visual
A Protocol to Recover Needles Lost During Minimally Invasive Surgery (2014)

On the basis of survey results and current literature, our protocol incorporates a camera survey of the abdomen, intraoperative fluoroscopic radiography, port inspection, and a quadrant-based systematic visual search for the recovery of needles lost during minimally invasive surgery.
Sequences from the aspergillopepsin<i>PEP</i>gene of<i>Aspergillus fumigatus</i>: evidence on their use in selective PCR identification of<i>Aspergillus</i>species in infected clinical samples (1999)

In immunodeficient patients, Aspergillus species emerge as circumstantial pathogens. Aspergillus fumigatus is a distant first among the pathogenic aspergilli, which cause deep-seated mycoses. Sequences of the pep gene of A. fumigatus as potential PCR primers, which have not been tested before, were used to identify this species and if possible, differentiate it from other, co-identified, clinically important species of the genus. We present results of the three most promising primer pairs, pep-1/pep-22, pep-15/pep-22 and pep-21/pep32. The second pair was of better specificity when tested with DNA extracted from pure cultures of a multitude of aspergilli, whereas the first co-amplified four clinically significant Aspergillus species. The compatibility of the PCR method with the CTAB DNA extraction protocol varied according to the biological fluid tested and the primer pair used. The first two pairs showed moderate adaptability to the different commercial DNA extraction kits, which were tested in whole blood, spiked with Aspergillus fumigatus hyphae and conidia - as were all the biological fluids used. Restriction of the amplification products with MspI produced distinct patterns for different Aspergillus spp. This approach, as a potential diagnostic tool, seems reliable and sensitive due to its flexibility, speed, low cost, ease of application and selectable breadth of detection.
Discovering Nature's Diverse Pathways to Vitamin B<sub>12</sub>:  A 35-Year Odyssey (2003)

The chronology of the discoveries along the pathway of vitamin B(12) biosynthesis is reviewed from a personal perspective, including discussion of the most recent finding that two pathways to B(12) exist-one aerobic and one anaerobic-which differ mainly in the ring contraction mechanisms that convert porphyrin to corrin.
Introduction to the physics of diagnostic radiology. 3rd edition (1984)

This book provides an introduction to the physics of imaging techniques used in diagnostic radiography. The authors have explained all formulas and physical principles before using them. The author reviews the concepts of production of x-rays and the attenuation of x-rays in the body, and then discusses the methods of detecting the attenuated x-ray beam; including grids, intensifying screens, film, and x-ray image intensifers. Specialized imaging techniques are discussed in detail, including xeroradiography, diagnostic ultrasound, digital fluoroscopy, computed tomography, and nuclear magnetic resonance.
Synthesis of 1-(D-Apio-β-D-furanosyl)-1,2,3-triazoles (1995)

1,2,3-Tri-O-acetyl-3'-O-benzoyl-D-apio-D-furanose (2) [β-2: α-2 =1.8:1], conveniently available in three steps from 2',3'-O-isopropylidene-D-apio-β-D-furanose (1), is transformed to the glycosyl azides 3 upon reaction with trimethylsilyl azide. The anomer β-3, separated from the minor component α-3 by chromatography, is transformed to a series of protected 1,2,3-triazole nucleosides 5 of D-apio-β-D-furanose upon reaction with 2-oxoalkylidene triphenylphosphoranes 4. Compounds 5 are deprotected to the corresponding nucleoside analogues 6 by transesterification with sodium methoxide-methanol. The carboxamide derivative 6f, which is structurally related to the antibiotic virazol, is obtained by ammonolysis of the ester derivative 6e.
Algebraic independence of periods and logarithms of Drinfeld modules (2011)

Let <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="rho"> <mml:semantics> <mml:mi>ρ</mml:mi> <mml:annotation encoding="application/x-tex">\rho</mml:annotation> </mml:semantics> </mml:math> </inline-formula> be a Drinfeld <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="upper A"> <mml:semantics> <mml:mi>A</mml:mi> <mml:annotation encoding="application/x-tex">A</mml:annotation> </mml:semantics> </mml:math> </inline-formula>-module with generic characteristic defined over an algebraic function field. We prove that all of the algebraic relations among periods, quasi-periods, and logarithms of algebraic points on <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="rho"> <mml:semantics> <mml:mi>ρ</mml:mi> <mml:annotation encoding="application/x-tex">\rho</mml:annotation> </mml:semantics> </mml:math> </inline-formula> are those coming from linear relations induced by endomorphisms of <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="rho"> <mml:semantics> <mml:mi>ρ</mml:mi> <mml:annotation encoding="application/x-tex">\rho</mml:annotation> </mml:semantics> </mml:math> </inline-formula>.
Explicit-Value Analysis Based on CEGAR and Interpolation (2012)

Abstraction, counterexample-guided refinement, and interpolation are techniques that are essential to the success of predicate-based program analysis. These techniques have not yet been applied together to explicit-value program analysis. We present an approach that integrates abstraction and interpolation-based refinement into an explicit-value analysis, i.e., a program analysis that tracks explicit values for a specified set of variables (the precision). The algorithm uses an abstract reachability graph as central data structure and a path-sensitive dynamic approach for precision adjustment. We evaluate our algorithm on the benchmark set of the Competition on Software Verification 2012 (SV-COMP'12) to show that our new approach is highly competitive. In addition, we show that combining our new approach with an auxiliary predicate analysis scores significantly higher than the SV-COMP'12 winner.
Optimized Lane Assignment Using Inter-Vehicle Communication (2007)

This paper presents an approach to lane assignment for highway vehicles that increases traffic throughput while ensuring they exit successfully at their destinations. Most of current traffic management systems do not consider lane organization of vehicles and only regulate traffic flows by controlling traffic signals or ramp meters. However, traffic throughput and efficient use of highways can be increased by coordinating driver behaviors intelligently. The goal of this research is to form a distributed control strategy for cars themselves to select lanes using inter-vehicle communication. Initial results are promising and demonstrate that intelligent lane selection can decrease vehicle traffic time.
On the key recovery of the Key Escrow System (2002)

The Key Escrow System (KES) bridges the gap between users' privacy and social needs for protection against criminal behavior. However, there are some disadvantages and controversies regarding the system. In this paper, we propose a new key escrow system, which not only meets the requirements of the KES but also provides a key recovery feature for users. The system can be implemented easily in software or hardware with familiar and tested public cryptographic functions that should significantly reduce controversy.
Soluble interleukin 2 receptors are released from the cell surface of normal murine B lymphocytes stimulated with interleukin 5. (1988)

Murine T and B lymphocytes can be induced to release soluble interleukin 2 receptors (IL2Rs). This receptor is believed to be a truncated form of the 55-kDa chain of the cell-membrane-associated receptor. It has been speculated that this receptor may play an important immunoregulatory role by binding to interleukin 2 (IL-2). We report here that interleukin 5 can induce normal murine B cells to release soluble IL2Rs. This extends our finding that interleukin 5 similarly can induce murine B cells to express functional cell-surface-associated IL2Rs. Two possible mechanisms of release of soluble IL2Rs have been suggested. Soluble IL2R could be synthesized as a secretory form of the receptor lacking the transmembrane domain or by cleavage of the extracellular domain of the cell-surface-associated IL2R at the cell surface. To investigate which mechanism was operative, we radioiodinated the cell surface of normal murine splenocytes that had been cultured for 1 day with Con A to stimulate the expression of cell-surface-associated IL2Rs and the release of soluble IL2Rs. Under the conditions used, radiolabeling of internal proteins was not apparent. Labeled cells were then recultured with Con A, conditioned medium was taken from replicate cultures at various times after radioiodination, and the specific radioactivity of released soluble IL2Rs was determined by ELISA and RIA. We demonstrate that the specific radioactivity and the kinetics of change of the specific radioactivity are consistent with the hypothesis that the soluble IL2Rs are derived from the cell-surface-associated IL2Rs rather than being released in a secretory form.