gebhart/patrepeval huggingface dataset:
Coherent orthogonal filter using pilot symbol-assistedchannel estimation for DS-CDMA (1996)

A coherent orthogonal filter (COF) using pilot symbol-assisted channel estimation is proposed for DS-CDMA cellular mobile radio. In the proposed scheme, a complex fading envelope in the multi-path environment is estimated using pilot symbols, and tap coefficients of orthogonal filter are controlled for maximising the signal to interference ratio (SIR) of a RAKE combined signal. Computer simulation results show that the required Eb/N0 of the proposed COF is reduced by ~10.0 dB compared to a conventional matched filter receiver at an average BER of 3 × 10-2 when there are 10 users and processing gain is 31.
Blockchain-Based Distributed Firmware Update Architecture for IoT Devices (2020)

The Internet of Things (IoT) which creates a hyper-connected society is playing a major role in the 4th industrial revolution. The IoT is being leveraged across various fields of business globally and the number of IoT devices is causing serious security concerns. Since the firmware update of an IoT device is necessary for its lifecycle, secure firmware update of the IoT device is being brought as the first step in IoT security. The Internet Engineering Task Force (IETF) Software Updates for Internet of Things (SUIT) working group has started to specify a software update architecture for IoT devices. However, the current SUIT working group adopts a traditional client-server model to distribute firmware images, which potentially causes security risks. The current approach of the SUIT working group is unable to solve a targeting issue and an author-disappearing issue, which is suggested in this paper. Therefore, in this work, we introduce a distributed firmware update architecture based on the SUIT firmware update architecture applying blockchain. Our update architecture can prevent the issues we concern through the characteristics of blockchain, such as decentralization, transparency, and irreversibility. The blockchain network has registration nodes that process registration of manifest and firmware image files from authors, and retrieval nodes that process downloading manifest and firmware image files. The firmware image files are stored in a distributed file system and the hash values of firmware image chunks are stored on the blockchain with manifest files. The proposed architecture in this paper enables the irreversible downloads even in the author-disappearing state and tolerant to a single point of failure.
ESD protection design for mixed-voltage I/O buffer with substrate-triggered circuit (2005)

A substrate-triggered technique is proposed to improve the electrostatic discharge (ESD) robustness of a stacked-nMOS device in the mixed-voltage I/O circuit. The substrate-triggered technique can further lower the trigger voltage of a stacked-nMOS device to ensure effective ESD protection for mixed-voltage I/O circuits. The proposed ESD protection circuit with substrate-triggered design for a 2.5-V/3.3-V-tolerant mixed-voltage I/O circuit has been fabricated and verified in a 0.25-/spl mu/m salicided CMOS process. The substrate-triggered circuit for a mixed-voltage I/O buffer to meet the desired circuit application in different CMOS processes can be easily adjusted by using HSPICE simulation. Experimental results have confirmed that the human- body-model (HBM) ESD robustness of a mixed-voltage I/O circuit can be increased /spl sim/60% by this substrate-triggered design.
Effet de l'acidité et des types d'azote sur la formation d'aérenchymes chez le riz (1992)

On a analysé sur des variétés aquatiques et pluviales de riz (Oryza sativa L.) l'effet complémentaire de différentes sources d'azote (nitro-ammoniacale, nitrique et ammoniacale), de la carence en azote et de l'acidité (pH 4,0) sur le développement d'aérenchymes dans les racines. En solution aérée, les variétés aquatiques n'ont pas plus d'aérenchymes que les variétés pluviales; néanmoins, le bon développement du cortex racinaire leur permet une meilleure adaptation en cas d'inondation. La formation des lacunes de la variété pluviale est provoquée par l'absence de nitrate; elle est aussi stimulée par la forte acidité. La variété aquatique développe moins d'aérenchymes que la variété pluviale en cas de carence en azote et en cas de forte acidité. On propose une hypothèse selon laquelle l'acidification du cytoplasme, plus faible chez les variétés aquatiques que chez les variétés pluviales, pourrait être la cause directe du développement d'aérenchymes
Phylogenomic analysis shows that Bacillus amyloliquefaciens subsp. plantarum is a later heterotypic synonym of Bacillus methylotrophicus (2015)

The rhizosphere-isolated bacteria belonging to the Bacillus amyloliquefaciens subsp. plantarum and Bacillus methylotrophicus clades are an important group of strains that are used as plant growth promoters and antagonists of plant pathogens. These properties have made these strains the focus of commercial interest. Here, we present the draft genome sequence of B. methylotrophicus KACC 13105(T) ( = CBMB205(T)). Comparative genomic analysis showed only minor differences between this strain and the genome of the B. amyloliquefaciens subsp. plantarum type strain, with the genomes sharing approximately 95% of the same genes. The results of morphological, physiological, chemotaxonomic and phylogenetic analyses indicate that the type strains of these two taxa are highly similar. In fact, our results show that the type strain of B. amyloliquefaciens subsp. plantarum FZB42(T) ( = DSM 23117(T) = BGSC 10A6(T)) does not cluster with other members of the B. amyloliquefaciens taxon. Instead, it clusters well within a clade of strains that are assigned to B. methylotrophicus, including the type strain of that species. Therefore, we propose that the subspecies B. amyloliquefaciens subsp. plantarum should be reclassified as a later heterotypic synonym of B. methylotrophicus.
Expression of p53 in human leukemia and lymphoma (1986)

Analysis of fresh human tumors have indicated that patients with B type lymphoproliferative diseases and the majority of patients with acute lymphoblastic leukemia (ALL) express elevated levels of p53 production. It is suggested that in these human malignancies, p53 may provide a novel tool for monitoring cancer activity. Conversely, p53 is not expressed in acute myeloid leukemias, myeloproliferative diseases, or myeloid leukemic cell lines. Analysis of the p53 gene structure indicated the existence of similar patterns of p53 restriction fragments in producer and nonproducer cells, which suggests that the p53 gene is not altered in the latter. However, in one case of acute promyelocytic leukemia (APL), we have observed a rearrangement in the p53 gene. Karyotype analysis has indicated that these APL cells do not contain the typical 15;17 translocation. In other APL patients who exhibit a 15;17 translocation, we found no genomic changes of the p53, suggesting that the p53 gene, which was recently mapped to the short arm of chromosome 17 in the human, is not structurally related to the typical chromosomal break point found in the long arm of chromosome 17 of APL patients.
Frequent occurrence of recombinant potyvirus isolates (1996)

We have performed a systematic search for recombination in the region encoding coat protein and the 3' non-translated region in natural isolates of potyviruses, the largest group of plant RNA viruses. The presence of recombination, and the localization of the cross-over points, were confirmed statistically, by three different methods. Recombination was detected or suspected in 18 out of 109 potyvirus isolates tested, belonging to four out of eight virus species, and was most prevalent in potato virus Y, clear in bean common mosaic virus, and possible in bean yellow mosaic and zucchini yellow mosaic viruses. Recombination was not detected in the four other potyvirus species tested, including plum pox virus, despite the availability of numerous sequences for this last species. Though it was not specifically researched, no evidence for inter-specific recombination was found. For several reasons, including the fact that only a minor portion of the genome was analysed, the above figures certainly represent an underestimate of the extent of recombination among isolates of potyviruses, which might thus be a common phenomenon.
Robust optimization for intensity modulated radiation therapy treatment planning under uncertainty (2005)

The recent development of intensity modulated radiation therapy (IMRT) allows the dose distribution to be tailored to match the tumour's shape and position, avoiding damage to healthy tissue to a greater extent than previously possible. Traditional treatment plans assume that the target structure remains in a fixed location throughout treatment. However, many studies have shown that because of organ motion, inconsistencies in patient positioning over the weeks of treatment, etc, the tumour location is not stationary. We present a probabilistic model for the IMRT inverse problem and show that it is identical to using robust optimization techniques, under certain assumptions. For a sample prostate case, our computational results show that this method is computationally feasible and promising-compared to traditional methods, our model has the potential to find treatment plans that are more adept at sparing healthy tissue while maintaining the prescribed dose to the target.
Cleavage-mediated Activation of Chk1 during Apoptosis (2008)

The Chk1 kinase is highly conserved from yeast to humans and is well known to function in the cell cycle checkpoint induced by genotoxic or replication stress. The activation of Chk1 is achieved by ATR-dependent phosphorylation with the aid of additional factors. Robust genotoxic insults induce apoptosis instead of the cell cycle checkpoint, and some of the components in the ATR-Chk1 pathway are cleaved by active caspases, although it has been unclear whether the attenuation of the ATR-Chk1 pathway has some role in apoptosis induction. Here we show that Chk1 is activated by caspase-dependent cleavage when the cells undergo apoptosis. Treatment of chicken DT40 cells with various genotoxic agents, UV light, etoposide, or camptothecin induced Chk1 cleavage, which was inhibited by a pan-caspase inhibitor, benzyloxycarbonyl-VAD-fluoromethyl ketone. The cleavage of Chk1 was similarly observed in human Jurkat cells treated with a non-genotoxic apoptosis inducer, staurosporine. We have determined the cleavage site(s), Asp-299 in chicken and Asp-299 and Asp-351 in human cells. We further show that a truncated form of human Chk1 mimicking the N-terminal cleavage fragment (residues 1-299) possesses strikingly elevated kinase activity. Moreover, the ectopic expression of Chk1-(1-299) in human U2OS cells induces abnormal nuclear morphology with localized chromatin condensation and phosphorylation of histone H2AX. These results suggest that Chk1 is activated by caspase-mediated cleavage during apoptosis and might be implicated in enhancing apoptotic reactions rather than attenuating the ATR-Chk1 pathway.
Nicotinic acid lariat ethers: syntheses, complexation, and reduction (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNicotinic acid lariat ethers: syntheses, complexation, and reductionGeorge R. Newkome and Charles R. MarstonCite this: J. Org. Chem. 1985, 50, 22, 4238–4245Publication Date (Print):November 1, 1985Publication History Published online1 May 2002Published inissue 1 November 1985https://pubs.acs.org/doi/10.1021/jo00222a011https://doi.org/10.1021/jo00222a011research-articleACS PublicationsRequest reuse permissionsArticle Views716Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A linear self-biased magnetoresistive head (1975)

Evaluation of the distortion resulting from imperfect biasing of a magnetoresistive (MR) read head shows that it is unacceptable in wide band recording systems. A general solution to the problem is presented which involves differentially sensed elements. A practical implementation and performance of a shielded head is discussed. Analytical techniques are shown for designing current-biased MR heads, which allow predictions of performance closely matching experimental results.
Optimization of H<sup>+</sup> Implantation Parameters for Exfoliation of 4H-SiC Films (2013)

In this study we show that for 1 µm thick 4H-SiC exfoliated films, there is an optimum implantation dose of about 6E16 cm-2 at 180 keV. The layer transfer is more difficult for higher as well as lower doses. Material doping and small changes in crystalline orientation do not have much impact on the exfoliation. Optical transmittance, Raman, RBS with ion channeling, SIMS, and optical microscopy are used for sample characterization.
VOCALOID - Commercial singing synthesizer based on sample concatenation (2007)

The song submitted here to the “Synthesis of Singing Challenge ” is synthesized by the latest version of the singing synthesizer “Vocaloid”, which is commercially available now. In this paper, we would like to present the overview of Vocaloid, its product lineups, description of each component, and the synthesis technique used in Vocaloid. Index Terms: singing synthesis 1.
Knowing where to look: ‘Meningococcal’ septicaemia following a dog bite (1999)

The patient presentation of septic shock and purpuric rash is commonly attributed to meningococcal septicaemia. We describe a case of similar presentation where initial cultures and antigen testing were negative for meningococcus and the isolation of an unusual organism, Capnocytophaga canimorsus , was only made after obtaining a history of a dog bite and liaison with the microbiology laboratory. The epidemiology and clinical features of Capnocytophaga canimorsus infection is discussed, together with the antibiotic management of dog bites.
Providing Information on the Spot: Using Augmented Reality for Situational Awareness in the Security Domain (2015)

For operational units in the security domain that work together in teams, it is important to quickly and adequately exchange context-related information to ensure well-working collaboration. Currently, most information exchange is based on oral communication. This paper reports on different scenarios from the security domain in which augmented reality (AR) techniques are used to support such information exchange. The scenarios have been designed with a User Centred Design approach, in order to make the scenarios as realistic as possible. To support these scenarios, an AR system has been developed and evaluated in two rounds. In the first round, the usability and feasibility of the AR support has been evaluated with experts from different operational units in the security domain. The second evaluation round then focussed on the effect of AR on collaboration and situational awareness within the expert teams. With regard to the usability and feasibility of AR, the evaluation shows that the scenarios are well defined and the AR system can successfully support information exchange in teams operating in the security domain. The second evaluation round showed that AR can especially improve the situational awareness of remote colleagues not physically present at a scene.
O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells (2013)

Metabolic disruptions that occur widely in cancers offer an attractive focus for generalized treatment strategies. The hexosamine biosynthetic pathway (HBP) senses metabolic status and produces an essential substrate for O-linked β-N-acetylglucosamine transferase (OGT), which glycosylates and thereby modulates the function of its target proteins. Here, we report that the HBP is activated in prostate cancer cells and that OGT is a central regulator of c-Myc stability in this setting. HBP genes were overexpressed in human prostate cancers and androgen regulated in cultured human cancer cell lines. Immunohistochemical analysis of human specimens (n = 1987) established that OGT is upregulated at the protein level and that its expression correlates with high Gleason score, pT and pN stages, and biochemical recurrence. RNA interference-mediated siliencing or pharmacologic inhibition of OGT was sufficient to decrease prostate cancer cell growth. Microarray profiling showed that the principal effects of OGT inhibition in prostate cancer cells were related to cell-cycle progression and DNA replication. In particular, c-MYC was identified as a candidate upstream regulator of OGT target genes and OGT inhibition elicited a dose-dependent decrease in the levels of c-MYC protein but not c-MYC mRNA in cell lines. Supporting this relationship, expression of c-MYC and OGT was tightly correlated in human prostate cancer samples (n = 1306). Our findings identify HBP as a modulator of prostate cancer growth and c-MYC as a key target of OGT function in prostate cancer cells.
Does the Number Matter: An Investigative Study of the Relationship Between Household Composition and Juvenile Delinquency (2003)

Single-parent households have been stigmatized and blamed for many social problems including increased rates of juvenile delinquency. I argue that single-parent households do not directly contribute to juvenile delinquency. Rather, socioeconomic status, the amount of human capital invested in each child, and parental involvement all play a significant role in the outcome being examined. Questionnaires received from 225 respondents will be analyzed so as to investigate the relationship between household resources and juvenile delinquency. I will examine the predictors of delinquency through an examination of twelve selected acts of delinquency.
Inflammatory bowel disease: a common cause of bloody diarrhoea in visitors to the tropics. (1985)

Has mortality related to alcohol decreased in Sweden?
Break It Down (2015)

A large, seemingly overwhelming task can sometimes be transformed into a set of smaller, more manageable microtasks that can each be accomplished independently. For example, it may be hard to subjectively rank a large set of photographs, but easy to sort them in spare moments by making many pairwise comparisons. In crowdsourcing systems, microtasking enables unskilled workers with limited commitment to work together to complete tasks they would not be able to do individually. We explore the costs and benefits of decomposing macrotasks into microtasks for three task categories: arithmetic, sorting, and transcription. We find that breaking these tasks into microtasks results in longer overall task completion times, but higher quality outcomes and a better experience that may be more resilient to interruptions. These results suggest that microtasks can help people complete high quality work in interruption-driven environments.
Transaction Management in Collaborative Virtual Environments (1999)

Collaborative Virtual Environments (CVEs) are groupware systems in which data are represented as objects in a virtual world. CVE supports activities ranging from software design and development to health care management where user operations are long in duration and intensive inhuman interaction. We found the advanced database transaction modeling and management technologies that have developed in the database community very useful in the design and development of CVE. In this paper, we first present a dynamically customizable transaction manager, JPern, then describe how a CVE could benefit from integrating with such a transaction management service. Finally, we describe an instance of CVE that we developed, CHIME, and how to integrate JPern with it.
Anti‐metastatic vaccination of tumor‐bearing mice with il‐2‐gene‐inserted tumor cells (1993)

IL-2 gene was introduced through retroviral vectors into the highly malignant and poorly immunogenic 3LL-D122 clone. Both high and low D122-IL-2 secretors showed elimination of tumorigenicity in syngeneic immune-competent mice; however, in nude mice only the high IL-2 secretor showed reduced tumorigenicity as compared with parental D122 cells. Also, following intravenous inoculation, only the high IL-2 secretor showed reduced generation of metastases, whereas the low IL-2 secretors were as highly metastatic as parental cells. These results seem to indicate that low levels of IL-2 secreted by tumor cells are sufficient to activate T cells, while higher levels are needed in order to activate non-T-cell effectors. D122-IL-2 secretors induced high levels of anti-tumor CTL, while their sensitivity to the lytic activity of these CTL was similar to the sensitivity of D122 cells, thus indicating that the elevation of immunogenicity of IL-2 secretors was essentially due to the secreted IL-2. In accordance with CTL induction, pre-immunization with IL-2 secretors protected mice against subsequent challenge of parental cells. Moreover, immunization in an "immunotherapy protocol" i.e., vaccination of mice carrying an established tumor of parental D122 cells with inactivated D122-IL2 infectants, almost completely eliminated the generation of lung metastases by D122 cells, thus providing a rationale for the use of IL-2 gene transferred tumor cells as a modality for treatment of metastasis.
Optical remote sensing for monitoring flying mosquitoes, gender identification and discussion on species identification (2018)

Mosquito-borne diseases are a major challenge for Human health as they affect nearly 700 million people every year and result in over 1 million deaths. Reliable information on the evolution of population and spatial distribution of key insects species is of major importance in the development of eco-epidemiologic models. This paper reports on the remote characterization of flying mosquitoes using a continuous-wave infrared optical remote sensing system. The system is setup in a controlled environment to mimic long-range lidars, mosquitoes are free flying at a distance of ~ 4 m from the collecting optics. The wing beat frequency is retrieved from the backscattered light from mosquitoes transiting through the laser beam. A total of 427 transit signals have been recorded from three mosquito species, males and females. Since the mosquito species and gender are known a priori, we investigate the use of wing beat frequency as the sole predictor variable for two Bayesian classifications: gender alone (two classes) and species/gender (six classes). The gender of each mosquito is retrieved with a 96.5% accuracy while the species/gender of mosquitoes is retrieved with a 62.3% accuracy. Known to be an efficient mean to identify insect family, we discuss the limitations of using wing beat frequency alone to identify insect species.