gebhart/patrepeval huggingface dataset:
Acoustic system for aircraft detection and tracking based on passive microphones arrays (2004)

The present study is conducted within a project included in the Sixth Framework Program of the European Union. The project, whose acronym is SAFE-AIRPORT, involves the development of an acoustic system based on two passive phased array microphone antennas, which are to be located in open environments, and capable of detecting and tracking airplanes at a distance in air and on ground. Each antenna array is made up of a series of microphones arranged on a rotating planar support. The Array’s spatial selectivity is discussed, aiming to optimize beamforming design according to spectral properties of common jet aircrafts. In particular, the influence of the number and the geometric distribution of microphones is shown in function of the target’s acoustic frequency and signal-to-noise ratio sensitivity. The system’s range is estimated at different working frequencies and for different positions of the aircraft on the horizon. The effect of wind gradients on the estimation of the aircraft position is also modeled, and computer simulations showing consequent deviation of acoustic waves are performed. Finally, possible developments in antenna design, such as the use of three fixed planar arrays in tetrahedral configuration instead of one rotating planar array, are evaluated showing expected advantages.
AN ALL-DIGITAL UNIVERSAL RF TRANSMITTER (2004)

This paper presents a CMOS Class D PA with on-chip alldigital RF modulator. The IC is fabricated in a 0.18 um digital CMOS process with MIM capacitors. The die size is a square 2.5 mm on each side. The active area used for the modulator (excluding the pads and bypass capacitance) is 0.315 mm'. The class D PA shows 75 dB IM, -50 dB feedthrough, and puts out 19.6 dBm at >69% drain efficiency fiom a 1.8 V supply. The modulator operates in the IQ domain, without the use of bias control nor envelope modulation.
Insulin-Like Growth Factor Binding Protein Secretion by Breast Carcinoma Cell Lines: Correlation with Estrogen Receptor Status* (1990)

Breast tumor cell lines have been shown to secrete several distinct polypeptide growth factors, although conflicting results exist for the insulin-like growth factors (IGFs). In contrast a limited number of breast tumor cell lines have definitely been shown to secrete the high affinity IGF binding proteins (IGFBPs) that modify IGF actions. To characterize the types of IGFBPs that are secreted by breast tumor cell lines, conditioned medium was collected from seven separate tumor cell lines, three of which were estrogen receptor (ER) negative, and four of which were ER positive. All three of the ER negative cell lines, MDA-231, MDA-330, and HS578T, secreted binding proteins of 49,000 and 43,000 Mr (IGFBP-3) as well as 29,000 (IGFBP-1) and 24,000 Mr. In contrast, all four ER positive cell lines secreted 34,000 (IGFBP-2) or 24,000 Mr forms, and none secreted the 49,000 and 43,000 or 29,000 Mr forms. BT-20, a cell line that is positive for ER messenger RNA (mRNA) but negative for ER protein, secreted predominantly a 34,000 Mr protein. The amount of total IGFBP activity released in 24 h ranged between 0.4 and 5.6 nM equivalents of IGFBP-1, and there was no significant difference between the ER positive and negative cell lines. The MCF-7 cells that produced predominantly 34,000 and 24,000 Mr forms showed a 1.8-fold increase in IGFBP secretion after estrogen stimulation. Immunoblotting and a specific RIA for IGFBP-1 showed that only the ER negative lines MDA-330, MDA-231, and HS578T secreted this form. Northern blotting analysis for the mRNA encoding this protein showed that both MDA-330 and MDA-231 contained a single 1.6 kilobase mRNA species that hybridized with an IGFBP-1 complementary DNA (cDNA) probe. Immunoblotting analysis of the other cell lines showed that only the 34,000 Mr form secreted by the ER positive cell lines reacted with IGFBP-2 antisera. Exposure of the conditioned media from the three ER negative cell lines to N-glycanase revealed that the 49,000 and 43,000 Mr forms of IGFBP were glycosylated and therefore probably represent IGFBP-3. We conclude that ER negative cell lines secrete three forms of IGFBPs, IGFBP-1, IGFBP-3, and a 24,000 Mr form. In contrast, the ER positive cell lines secrete predominantly IGFBP-2 and the 24,000 Mr form but do not secrete IGFBP-3 or 1.(ABSTRACT TRUNCATED AT 400 WORDS)
Principle of Doppler Tissue Velocity Measurements (1995)

Doppler signals from ventricular wall motion differ from signals of blood flow (moving red blood cells) in two major respects.
Sensor registration technique for passive location system (2009)

A general least-squares (GLS) passive sensor registration algorithm is studied for passive location system. At first, the position error model of passive location system is proposed; then, based on the error model, a linear measure model is constructed for the angle system error of passive sensor, and the GLS is utilized for estimating the biases. Simulation results show that the method can effectively estimate the angle biases for passive location system. (4 pages)
Clearance of a Persistent Human Enterovirus Infection of the Mouse Central Nervous System by the Antiviral Agent Disoxaril (1989)

Enteroviruses can cause persistent central nervous system (CNS) infections in agammaglobulinemic individuals. Because these infections are rarely cured by passive administration of antibody, a chemotherapeutic approach would be advantageous. In this study, the efficacy of the antienterovirus (and antipicornavirus) drug disoxaril was demonstrated in a murine model of persistent enterovirus infection. Disoxaril is a hydrophobic antiviral compound that blocks picornavirus uncoating. The W-2 strain of human poliovirus type 2 (PV2) persists in the CNS of immunosuppressed mice and causes late paralysis. Mice were inoculated intracerebrally with PV2, immunosuppressed with cyclophosphamide, and treated intragastrically with disoxaril at 50, 100, or 200 mg/kg per day in two divided doses beginning on postinfection day 20. At 200 mg/kg per day, disoxaril significantly decreased the incidence of clinical disease, i.e., paralysis and death. Assays for virus revealed more rapid clearance of virus from the CNS in the drug-treated group. No drug-associated toxicity was observed. Residual isolates of virus were not drug-resistant, suggesting that the appearance of drug resistance during prolonged treatment may not be a clinical problem.
Bone Ingrowth into Pores of Lotus Stem-Type Bioactive Titanium Implants Fabricated Using Rapid Prototyping Technique (2010)

International audience
Low-temperature Pyrex glass wafer direct bonding (1995)

The authors focus on the low-temperature direct bonding of Pyrex glass wafers. A hydrophilic treatment has been used to decrease the process temperature. After a final heat treatment at 350°C, a tensile strength of ~250 kgf/cm2 has been measured.
A controlled study of primary fibromyalgia syndrome: clinical features and association with other functional syndromes. (1989)

One hundred and thirteen patients with primary fibromyalgia syndrome, 77 with rheumatoid arthritis (RA) and 67 healthy controls without significant aches or pains were studied by protocol to determine clinical features of primary fibromyalgia syndrome and to assess the possible association of primary fibromyalgia syndrome with common functional disorders compared with the control groups. Previously reported common features of primary fibromyalgia syndrome are confirmed in this controlled study. In addition the extent of cutaneous hyperemia on palpation was found to be greater in patients with primary fibromyalgia syndrome than in normal controls. All the 3 functional syndromes evaluated, e.g., irritable bowel, chronic functional headache and primary dysmenorrhea, were significantly (p less than 0.005) more common in primary fibromyalgia syndrome, compared with RA and normal control groups. These data suggest that primary fibromyalgia syndrome is a characteristic clinical condition that overlaps with other well recognized functional syndromes.
Lutein and Zeaxanthin Protect Photoreceptors from Apoptosis Induced by Oxidative Stress: Relation with Docosahexaenoic Acid (2007)

These results show for the first time the direct neuroprotection of photoreceptors by xanthophylls and suggest that ZEA and LUT, along with DHA, are important environmental influences that together promote photoreceptor survival and differentiation.
Nutrition counseling skills for the nutrition care process (2008)

Through appropriate counseling and intervention, nutritionists play an important role in encouraging clients to make and maintain dietary changes. Nutrition Counseling Skills for Medical Nutrition Therapy provides the latest counseling theory and communication techniques for clinical and community settings. The Fourth Edition focuses on tailoring intervention strategies to a client's dietary needs through effective interviewing, assessing, and counseling. This revision of a popular text addresses nutrition counseling for conditions such as obesity, heart disease, diabetes, renal disease, hypertension, cancer, eating disorders, and pregnancy.
Possible immunological disorders in autism: concomitant autoimmunity and immune tolerance. (2006)

Autism is a pervasive developmental disorder that affect children early in their life. Immunological disorders is one of several contributing factors that have been suggested to cause autism. Thirty autistic children aged 3-6 years and thirty non-autistic psychologically-free siblings were studied. Circulating IgA and IgG autoantibodies to casein and gluten dietary proteins were detected by enzyme-immunoassays (EIA). Circulating IgG antibodies to measles, mumps and rubella vaccine (M.M.R) and cytomeglovirus were investigated by EIA. Results revealed high seropositivity for autoantibodies to casein and gluten: 83.3% and 50% respectively in autistic children as compared to 10% and 6.7% positivity in the control group. Surprisingly, circulating anti-measles, anti-mumps and anti-rubella IgG were positive in only 50%, 73.3% and 53.3% respectively as compared to 100% positivity in the control group. Anti-CMV IgG was positive in 43.3% of the autistic children as compared to 7% in the control group. It is concluded that, autoimmune response to dietary proteins and deficient immune response to measles, mumps and rubella vaccine antigens might be associated with autism, as a leading cause or a resulting event. Further research is needed to confirm these findings.
Acousto-Optic Accessing in Optical Disks (1989)

An acousto-optic deflector has been used as a fine actuator to improve the ability to pull in a track. Combining this A/O system with split optics which make it possible to get high acceleration, we have achieved an access time without latency of 14 ms in a 12'' optical disk system.
Antioxidant Effect of Zinc on Acute Renal Failure Induced by Ischemia-Reperfusion Injury in Rats (1999)

Zinc may have an antioxidant effect mediated by induction of metallothionein. Based on the assumption that metallothionein can scavenge oxygen free radicals, we examined whether zinc administration prior to renal ischemia would improve renal dysfunction caused by ischemia-reperfusion injury in rats. Wistar rats weighing 265 g were treated with an intraperitoneal injection of 20 mg/kg zinc 24 h prior to the renal ischemia-reperfusion procedure, which was achieved by a 30-min clamping of the bilateral renal vessels and subsequent 90-min reperfusion. Thirty-minute renal clearance tests were performed before and after renal ischemia in zinc- (n = 11) and saline-treated (n = 8) rats. Thiobarbituric acid reactive substance, conjugated diene, and metallothionein levels in the renal tissues were also determined. Sham-operated rats (n = 5 in each treatment) served as control for the ischemia-reperfusion rats. Ischemia-reperfusion resulted in significantly lower glomerular filtration rate values and marked increases in tissue concentrations of thiobarbituric acid reactive substance and conjugated diene compared with sham-operation. Zinc administration improved the reduced glomerular filtration rate values seen after the ischemia-reperfusion procedure, but not to the extent of pre-ischemic levels. Zinc pretreatment significantly reduced the increased levels of thiobarbituric acid reactive substance and conjugated diene during ischemia-reperfusion and increased metallothionein levels compared with saline injection. These findings suggest that zinc has an antioxidant effect mediated through the induction of metallothionein, but appears only to have a minor protective effect on renal function induced by renal ischemia-reperfusion injury.
An iterative sequential mixed-integer approach to automated prostate brachytherapy treatment plan optimization (2000)

Conventional treatment planning for interstitial prostate brachytherapy is generally a `trial and error' process in which improved treatment plans are generated by iteratively changing, via expert judgement, the configuration of sources within the target volume in order to achieve a satisfactory dose distribution. We have utilized linear mixed-integer programming (MIP) and the branch-and-bound method, a deterministic search algorithm, to generate treatment plans. The rapidity of dose falloff from an interstitial radioactive source requires fine sampling of the space in which dose is calculated. This leads to a large and complex model that is difficult to solve as a single 3D problem. We have therefore implemented an iterative sequential approach that optimizes pseudo-independent 2D slices to achieve a fine-grid 3D solution. Using our approach, treatment plans can be generated in 20-45 min on a 200 MHz processor. A comparison of our approach with the manual `trial and error' approach shows that the optimized plans are generally superior. The dose to the urethra and rectum is usually maintained below harmful levels without sacrificing target coverage. In the event that the dose to the urethra is undesirably high, we present a refined optimization approach that lowers urethra dose without significant loss in target coverage. An analysis of the sensitivity of the optimized plans to seed misplacement during the implantation process is also presented that indicates remarkable stability of the dose distribution in comparison with manual treatment plans.
Application of Extreme Value Statistics to the Prediction of Maximum Pit Depth in Non-Piggable, Buried Pipelines (2008)

Currently, the reliability of non-piggable pipelines is mainly assessed either from historical failure data or from the results of direct assessment evaluations. When external, localized corrosion is the main threat to the pipeline integrity, the most important factor in assessing the reliability of a pipeline segment is the distribution of maximum pit depths. This distribution cannot be directly derived from historical failure data, nor from the information obtained from external corrosion direct assessment. In contrast, the statistical modeling of extreme values could be used to predict the distribution of pit depth maxima in a pipeline from a relatively small number of maximum pit depths measured at excavation sites along its length. Despite of the large number of works aimed at the application of the extreme value statistics, there is a lack of studies devoted to the applicability of the method for prediction of the maximum pit depth for the pit densities and pit spatial patterns typical of long buried pipelines. In this work, Monte Carlo simulations were conducted in order to assess the statistical errors associated with the prediction of the maximum pit depth for a wide range of the number and size of the inspection areas, pits per unit area and pit spatial patterns. As a result, the optimum area of inspection is proposed. The Monte Carlo numerical experiments were run by using synthetic and real corrosion data acquired by magnetic flux leakage and ultrasonic in-line inspection (ILI) tools, an approach that has not been reported in previous studies. The ILI data was sampled using standard methods of extreme value analysis, and the predicted maximum pit depth was compared with that reported by the in-line inspection. Monte Carlo simulations with synthetic and real corrosion data have allowed assessing the influence of the number and size of the inspected areas on the accuracy of predictions when pits distribute homogeneously and non-homogeneously in the pipeline. It is shown that, when the distribution of pits is homogeneous, the accuracy in the maximum pit depth prediction using the proposed method is similar to the measurement errors associated with magnetic flux leakage ILI tools.
Gambicin: A novel immune responsive antimicrobial peptide from the malaria vector <i>Anopheles gambiae</i> (2001)

A novel mosquito antimicrobial peptide, gambicin, and the corresponding gene were isolated in parallel through differential display-PCR, an expressed sequence tag (EST) project, and characterization of an antimicrobial activity in a mosquito cell line by reverse-phase chromatography. The 616-bp gambicin ORF encodes an 81-residue protein that is processed and secreted as a 61-aa mature peptide containing eight cysteines engaged in four disulfide bridges. Gambicin lacks sequence homology with other known proteins. Like other Anopheles gambiae antimicrobial peptide genes, gambicin is induced by natural or experimental infection in the midgut, fatbody, and hemocyte-like cell lines. Within the midgut, gambicin is predominantly expressed in the anterior part. Both local and systemic gambicin expression is induced during early and late stages of natural malaria infection. In vitro experiments showed that the 6.8-kDa mature peptide can kill both Gram-positive and Gram-negative bacteria, has a morphogenic effect on a filamentous fungus, and is marginally lethal to Plasmodium berghei ookinetes. An oxidized form of gambicin isolated from the cell line medium was more active against bacteria than the nonoxidized form from the same medium.
RECURRING DIGITAL FIBROMAS OF INFANCY * (1985)

SUMMARY Recurring digital fibromas are distinguished by their occurrence in infants, their almost exclusive predilection for the fingers and toes, their tendency to recur and their characteristic inclusion bodies. At the Royal Alexandra Hospital for Children (RAHC) thirty cases were seen in thirty‐six years. The patients were twenty females and ten males, aged 0–7 years, including two with congenital lesions. The fingers and toes were equally affected, and one unusual case involved the side of the hand. Multiple lesions occurred in 50% of patients, more often on the fingers, especially on adjacent fingers (six cases) and two patients had bilateral lesions. Although some lesions had infiltrated down to the periosteum, no metastases occurred in our series, or in the cases in the literature. As growth rate may be alarming, some of these tumours have been treated aggressively, but evidence suggests that a conservative approach should be followed.
Insect Control by Use of Recombinant Baculoviruses Expressing Juvenile Hormone Esterase (1993)

Anti-juvenile hormone activity, and the resulting cessation of feeding, has long been considered by the agricultural chemical industry as a means for insect control. Juvenile hormone esterase (JHE) contributes to the decline in JH titer at certain times during larval development. This chapter reviews the efforts made to develop a fast acting recombinant baculovirus insecticide by creating a virus which will express artificially high levels of JHE in the insect at inappropriate times. The findings are discussed in the light of our current understanding of the regulation of larval development and the role of JHE. Prospects for the newly developed, highly effective baculoviruses expressing modified forms of JHE are also considered.
Adaptive subtraction using complex-valued curvelet transforms (2010)

Abstract We propose a complex-valued curvelet transform-based (CCT-based) algorithm that adaptively subtracts from seismic data those noises for which an approximate template is available. The CCT decomposes a geophysical data set in terms of small reflection pieces, with each piece having a different characteristic frequency, location, and dip. One can precisely change the amplitude and shift the location of each seismic reflection piece in a template by controlling the amplitude and phase of the template's CCT coefficients. Based on these insights, our approach uses the phase and amplitude of the data's and template's CCT coefficients to correct misalignment and amplitude errors in the noise template, thereby matching the adapted template with the actual noise in the seismic data, reflection event-by-event. We also extend our approach to subtract noises that require several templates to be approximated. By itself, the method can only correct small misalignment errors (±5ms in 50-Hz data) in the template; it relies on conventional least-squares (LS) adaptation to correct large-scale misalignment errors, such as wavelet mismatches and bulk shifts. Synthetic and real-data results illustrate that the CCT-based approach improves upon the LS approach and a curvelet-based approach described by Herrmann and Verschuur.
Sonar and radar SAR processing for parking lot detection (2011)

Abstract: In this paper, SAR processing algorithms for automotive applications are presented and illustrated on data from non-trivial test scenes. The chosen application is parking lot detection. Laboratory results obtained with a teaching sonar experiment emphasize the resolution improvement introduced with range-Doppler SAR processing. A similar improvement is then confirmed through full scale measurements performed with an automotive radar prototype operating at 77GHz in very close range conditions, typical of parking lot detection. The collected data allows a performance comparison between different SAR processing algorithms for realistic targets. 1.
A Combined Theoretical and Experimental Study of the Influence of Different Anion Ratios on Lithium Ion Dynamics in Ionic Liquids (2014)

In this paper, we investigate via experimental and simulation techniques the transport properties, in terms of total ionic conductivity and ion diffusion coefficients, of ionic liquids doped with lithium salts. They are composed of two anions, bis(fluorosulfonyl)imide (FSI) and bis(trifluoromethanesulfonyl)imide (TFSI), and two cations, N-ethyl-N-methylimidazolium (emim) and lithium ions. The comparison of the experimental results with the simulations shows very good agreement over a wide temperature range and a broad range of compositions. The addition of TFSI gives rise to the formation of lithium dimers (Li(+)-TFSI(-)-Li(+)). A closer analysis of such dimers shows that involved lithium ions move nearly as fast as single lithium ions, although they have a different coordination and much slower TFSI exchange rates.
A Simple Conversion of Polyols into Anhydroalditols (1994)

A simple procedure, which consists of direct heating of pyridinium chloride and the starting material, is described for the dehydration of alditols. Anhydroalditols, of great interest for various applications, are thus obtained, and the selectivity of the reaction is discussed. Some selective protections for further uses of these products are studied.