gebhart/patrepeval huggingface dataset:
Isolation of Ethyl p-methoxycinnamate, the major antifungal principle of Curcumba zedoaria. (1976)

An antifungal principle of the dried rhizomes of Curcuma zedoaria was extracted with hot ethanol. By successive chromatography on neutral alumina and silica gel, three antibiotic compounds A, B, and C, all active against Trichophyton rubrum, Aspergillus niger and Saccharomyces cerevisiae, were obtained in chemically pure form. By uv, ir, pmr and ms analysis, the structure of the most abundant one of these compounds (C, 69.8%; H, 6,8%; and 0.23.4%) was assigned as ethyl p-methoxycinnamate (EPMC). The proposed structure was confirmed by synthesis and comparison of the chemical and biological properties of the natural and synthetic products. EPMC inhibits the growth of Trichophyton rubrum, Aspergillus niger, Saccharomyces cerevisiae and Epidermophyton floccosum at a concentration less than 10 mug/ml; A. fumigatus, Penicillium purpurogenum, Trignoposis variabilis, Microsporum gypseum, Sclerotium rolifsii, Geotricular candiade, Fusarium oxysporum and Helminthosporium oryzale at a concentration less than 25 mug/ml; and Candida krusei and T. mentagrophytes At a concentration less than 50 mug/ml. The spores of T. rubrum Lose viability or ability to germinate when wxposed to its ethanolic solution (30 mug/ml) for 2 hours.
Detection of mutations in Salmonella entericagyrA, gyrB, parC and parE genes by denaturing high performance liquid chromatography (DHPLC) using standard HPLC instrumentation (2005)

The results demonstrated that a non-specialist standard HPLC machine fitted with a generally available column can be used to detect SNPs in gyrA, gyrB, parC and parE genes by DHPLC. Wider applications should be possible.
Multiple query optimization in PBASE/3 (2000)

We propose a multi-phase multi-query optimization approach (MMO) for parallel databases. MMO takes multiple objectives into account. It overcomes the limitations of two-phase and one-phase approaches, and can be easily integrated into the traditional optimizer. We discuss the strategies and algorithms for searching common operators, rewriting queries, and cost-based optimization in MMO. Theoretic analysis proves that the efficiency of the MMO optimizer is high and the searching strategies for common operators have little influence on the performance.
Impact of Startup Purge Credit on Combined Cycle Plant Operation (2015)

Normal boiler and Heat Recovery Steam Generator Operation have required a complete purge of the boiler by fresh air before startup firing to remove potentially explosive fuels and other substances from the boiler/HRSG. For power plants in daily two-shift cycling (or more frequent starts) this not only adds time to the startup sequence but can impose significant thermal stresses on hot components exposed to cooler purge air. Since the approval of a purge credit mode in NFPA 85 (2011) where the flow of air through the HRSG during shutdown can be credited as a purge, plants can operating without a startup purge with enhanced fuel systems and operating procedures. This paper will look at the impact of purge (and purge credit) on the thermal stress and fatigue lifetimes of HRSG operating with and without purge credit. Data and simulation results will demonstrate the range of fatigue life changes from implementation of purge credits as well as other operational impacts as seen in operating data.
'Wil' Power: Jeremy Weinstein on Making his First Feature Film (2007)

First time feature film director Jeremy Weinstein, talks about his film 'Wil' and the the differences in directing feature films and short films. He also gives advice on what it takes to direct a feature in Australia and how confidence and lack of fear are the two main attributes a first time director should possess.
Application Analysis of Computer Software Security Vulnerability Detection Based on Web Crawler (2021)

With the rapid development of the Internet, the World Wide Web has become a carrier of a large amount of information. In order to effectively extract and use this information, web crawlers that crawl various web resources have emerged. The interconnectedness, openness, and interactivity of information in the World Wide Web bring great convenience for information sharing to the society and they also bring many security risks. To protect resource information, computer software security vulnerabilities have become the focus of attention. This article is based on the method of computer software security detection under a web crawler simply analyzes the basic concepts of computer software security detection and analyzes the precautions in the process of security detection. Finally, combined with the computer software security vulnerability problems in the web crawler environment, its security detection technology Application for further analysis.
Removal of History (1995)

In regarding history as a concept, the foundation of both the critical and the cultural historian relies on the metaphor selected to order the world. The acquisition of knowledge by inquiry, as in the Greek “historia”, is related to the Latin “videre” ( to see), and develops an historical sense which includes the perception of the past, the present, and the future simultaneously. These relationships of time usually move either horizontally as a chronological time line with clear regulations and overlaps; or vertically with the direct impact of a cut or incision that both divides and links at the same time. A ruin is a state of time where, for a moment, all three tenses collide as the past and the future crash into the present. In a ruin both the productions and the destructions of history reveal themselves as an opportunity to recognize the significance and signatures of events and the boundaries enclosing them.
A time-based CMOS image sensor (2004)

A two-degree of freedom time-based CMOS image sensor is proposed in this paper for wide dynamic range imaging. Instead of reading analog voltages off chip, a time representation is used to record when the photodetector voltage drops below a time-varying threshold. The time measurements and the reference voltage waveform are used to reconstruct the image. Experimental results verify that the two-degree of freedom sampling technique is feasible for wide dynamic range imaging in video mode.
Manganese Porphyrin-dsDNA Complex: A Mimicking Enzyme for Highly Efficient Bioanalysis (2013)

Manganese porphyrin (MnTMPyP)-dsDNA complex was reported as an excellent mimicking enzyme of peroxidase. It possessed high catalytic activity and much quicker catalytic kinetics and better stability with exposure to light irradiation and high temperature than both horseradish peroxidase and hemin/G-quadruplex DNAzyme. The groove binding of MnTMPyP to the dsDNA scaffold efficiently maintained the catalytic activity of the MnTMPyP center and improved its stability. By combining with an isothermal hybridization chain reaction (HCR) and in situ formation of MnTMPyP-dsDNA, a highly efficient chemiluminescent (CL) immunosensing method was proposed. After a sandwich immunoreaction, a biotinylated DNA strand, which was bound to biotinylated signal antibody by streptavidin, triggered the HCR and growth of MnTMPyP-dsDNA on the immunocomplex. The in situ, HCR-assisted enzyme formation brought numerous enzymatic catalytic centers, MnTMPyP, on the immunocomplex, resulting in significant CL signal amplification and highly sensitive CL detection. Using carcinoembryonic antigen as the model target, the proposed CL immunoassay method showed a wide linear range from 10 pg/mL to 100 ng/mL with a detection limit of 6.8 pg/mL. The new MnTMPyP-dsDNA complex could be conveniently synthesized, functionalized, and combined with DNA amplification strategies, showing a promising potential in bioanalysis and other relative fields.
Satellite Observations During the Rapid Intensification of Hurricane Camille (1973)

Medium resolution infrared radiometer observations at the 6.7 micrometer and the 11 micrometer regions by satellite during the maximum intensification phase of hurricane Camille show increasing black body temperatures near the center. This is attributed to increased upward vertical motion in the interior of the cyclone, which is an indication of rapid intensification.
<sup>13</sup>C NMR sequence analysis, 20. Stereospecificity of the polymerization of <scp>D</scp>,<scp>L</scp>‐Leu‐NCA and <scp>D</scp>,<scp>L</scp>‐Val‐NCA (1981)

Abstract The copolymerization of D ‐ and L ‐Leu‐NCA as well as that of D ‐ and L ‐Val‐NCA was studied under various conditions. Even nonpolar solvents, such as diethyl ether or ligroin, used for the precipitation of the poly( D , L ‐amino acid)s, were found to have an influence on yield and tacticity of the isolated polypeptides indicating that atactic polypeptides of low molecular weight may be soluble in these solvents. 13 C NMR spectra of the isolated poly( D , L ‐amino acid)s were measured in trifluoroacetic acid and the carbonyl signals were used for the evaluation of the teacticity. Under all reaction conditions only a moderate degree of stereospecificity was found. D , L ‐Leu‐NCA initiation with protic nucleophiles, such as benzylamine or diethylamine, favors the formation of isotactic blocks. In the case of D , L ‐Val‐NCA again isotactic blocks are slightly favored if benzylamine is used as initiator, while diethylamine, like other strong bases, causes preferred formation of syndiotactic sequences. With strong aprotic bases and electrophilic cocatalysts, i.e. under conditions favoring the “activated monomer mechanism”, the highest degrees of stereospecificity were observed. However, in the case of D , L ‐Leu‐NCA isotactic blocks are predominantly formed, while in the case of D , L ‐Val‐NCA syndiotactic blocks are favoured. Changing the solvent may result in a reversal sense of the stereospecificity. The absence of long isotactic blocks in all samples of this work was also demonstrated by the good solubility of all samples in various organic solvents.
The FU Decision: Reflections on Antisocial Role Development (1995)

The manner in which influences that lead to the FU decision by certain individuals, which result in their antisocial behaviour, can be brought out using psychodrama is discussed. The key role of Role Theory and Transactional Analysis (TA) in enabling cognitive development of such individuals is highlighted.
The Raman spectrum of gaseous acetic acid at 21 °C (1982)

The Raman spectrum of gaseous acetic acid at 21 °C is presented and assigned. It is suggested that a reassignment of the in-plane C–C–O deformation of the monomer to ∼450 cm−1 is appropriate, and that the infrared band contours between 700 and 400 cm−1 be analyzed in detail to confirm this. The Raman-active O–H stretching mode of the dimer could not be identified. The intermonomer coupling of the other intramonomer modes in the dimer is small except for the C=O stretching and C–C–O in-plane deformation modes. Two Raman-active intermonomer modes were observed for the first time, at 155 and 99 cm−1. The former is ν13(Ag), the O⋅⋅⋅O stretching mode, and allows the previously [J. Chem. Phys. 76, 886 (1982)] unobserved corresponding mode of (HCOOH)2 to be placed near 180 cm−1. Frequencies are deduced of all of the intermonomer modes, and the infrared doublet at 167/187 cm−1 is reassigned to ν42(Bu) in Fermi resonance with the combination state ν21(Bg)+ν28(Au) at ∼179 cm−1, instead of the previously assigned combination state ν29(Au)+ν21(Bg) which is now placed at 147 cm−1. The Fermi resonance explanation of the infrared doublet at 167/187 cm−1 invokes significant anharmonic interactions between in-plane and out-of-plane displacements of the hydrogen bond. It is favored by the experimental facts over the explanation that is based on coupling between the O–H and O⋅⋅⋅O stretching coordinates [J. Chem. Phys. 52, 4403 (1970)], which is not clearly compatible with the C2h symmetry of the dimer. Our assignment of the intermonomer bands of the gaseous dimer is similar to that deduced previously for matrix-isolated dimers [J. Chem. Phys. 54, 4111 (1971)] and for liquid acetic acid [J. Chem. Phys. 77, 3878 (1982)]. However, the band at 55 cm−1 in the Raman spectrum of the liquid has no analog in the spectrum of the gas, and is reassigned to an intermolecular vibration of the ‘‘liquid lattice’’. Further, our assignment differs from that for the matrix-isolated dimers in a way that is unfavorable to the interpretation of the O–H stretching band that led to the assignment of the matrix-isolated dimers. Finally, manual correction of the Raman intensities of gaseous formic and acetic acids, for frequency- and temperature-dependent factors, suggests that the vibrations below 150 cm−1 may have frequencies higher by up to 20 cm−1 than the values measured from the Raman spectra.
Synthesis and Binding Properties to GABA Receptors of 3‐Hydroxypyridinyl‐ and 3‐Hydroxypiperidinyl‐Analogues of Baclofen (1992)

The synthesis of 3-(3-hydroxy-2-pyridinyl)propanoic acid, 3-(3-hydroxy-2-pyridinyl)-4-aminobutanoic acid, their corresponding piperidine compounds, and of some cyclized derivatives is described. In in vitro assays none of the new compounds shows any noteworthy affinity for GABAA or GABAB receptors; only (R,S)-3-(3-hydroxy-2-pyridinyl)-4-aminobutanoic acid and its lactam inhibited in some degree [3H]GABA binding, at 10(-4) M concentration, with low specificity as regards the two receptors.
A cell phone and a Chinese curse (2010)

A hunger strike is a common, expensive, and potentially lethal event within a correctional institution. In this study, we describe the characteristics of inmates who initiated hunger strikes in a state prison system. Electronic medical records for a state prison system were reviewed for documentation of hunger strikes from January 2005 through September 2015. There were 292 hunger strikes during the study period. Most (71%) lasted three or fewer days. When weight data were available, only 12.9 percent of the hunger strikes resulted in a weight loss >10 percent. Mental health patients were disproportionately represented in the sample (45%), although diagnoses of personality disorders (48%) rather than mood (17%) or psychotic (10%) disorders accounted for most of these cases. Nearly 75 percent of inmates who initiated hunger strikes did so while residing in disciplinary housing. In more than 80 percent of the strikes, the reason for stopping the strike was unknown. When the reasons were known, custody intervention rather than mental health intervention was the most common reason for the ending of a strike. Improving communication with custody administration and mitigating unnecessarily aversive housing environments are likely to reduce the incidence of hunger strikes.
The Cryogenics of a Thermosiphon-Cooled HTS MRI Magnet—Assembly and Component Testing (2010)

The team at GE Global Research presents cryo assembly and component test results of a high-temperature superconducting (HTS) limb size magnetic resonance imaging (MRI) scanner using Sumitomo's DI-BSCCO tape conductor, under an NIH research grant. The goal is to investigate the thermosiphon behavior for different MRI operating modes, validating the cryogenic robustness of this cooling approach and its performance limits. The magnet is indirectly cooled using cooling tubes with liquid neon filling and a single-stage cryocooler for reliquefying.
A liquid chromatography‐tandem mass spectrometry method for the simultaneous determination of exemestane and its metabolite 17‐dihydroexemestane in human plasma (2009)

A simple and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the quantitation of exemestane (Exe) and its main metabolite 17-dihydroexemestane (DhExe) in human plasma. The analytes were extracted by protein precipitation with acetonitrile, containing stable 13C-labelled Exe (13C3-Exe) as internal standard, and measured by LC-MS/MS. The best chromatographic separation of the analytes from the interferences was achieved by using a Phenyl column operating under isocratic regime conditions. The total chromatographic runtime was 5.0 min and the elution of Exe and DhExe occurred at 2.5 min and 2.9 min, respectively. Quantitation was performed by employing the positive electrospray ionization (ESI) technique and multiple reaction monitoring mode (MRM). The monitored precursor to product-ion transitions for Exe, DhExe and 13C3-Exe internal standard were m/z 297.0 --> 120.8, m/z 299.1 --> 134.9 and m/z 300.0 --> 123.2, respectively. The lower limit of quantitation (LLOQ) was 0.1 ng/ml for DhExe and 0.2 ng/ml for Exe. The method was linear up to 36-51 ng/ml with r2 > or = 0.998. The intra- and inter-assay precision were < or = 7.7% and 5.1% for Exe and < or = 8.1 and 4.9% for DhExe while deviations from nominal values were in the 1.5-13.2% and - 9.0-5.8% ranges for Exe and DhExe, respectively. The analytical method resulted robust and suitable for pharmacokinetic monitoring of Exe and its main metabolite during adjuvant therapy in patients with breast cancer.
NeuroM, a neural helix-loop-helix transcription factor, defines a new transition stage in neurogenesis (1997)

Genes encoding transcription factors of the helix-loop-helix family are essential for the development of the nervous system in Drosophila and vertebrates. Screens of an embryonic chick neural cDNA library have yielded NeuroM, a novel neural-specific helix-loop-helix transcription factor related to the Drosophila proneural gene atonal. The NeuroM protein most closely resembles the vertebrate NeuroD and Nex1/MATH2 factors, and is capable of transactivating an E-box promoter in vivo. In situ hybridization studies have been conducted, in conjunction with pulse-labeling of S-phase nuclei, to compare NeuroM to NeuroD expression in the developing nervous system. In spinal cord and optic tectum, NeuroM expression precedes that of NeuroD. It is transient and restricted to cells lining the ventricular zone that have ceased proliferating but have not yet begun to migrate into the outer layers. In retina, NeuroM is also transiently expressed in cells as they withdraw from the mitotic cycle, but persists in horizontal and bipolar neurons until full differentiation, assuming an expression pattern exactly complementary to NeuroD. In the peripheral nervous system, NeuroM expression closely follows cell proliferation, suggesting that it intervenes at a similar developmental juncture in all parts of the nervous system. We propose that availability of the NeuroM helix-loop-helix factor defines a new stage in neurogenesis, at the transition between undifferentiated, premigratory and differentiating, migratory neural precursors.
SOURCE OF ESTROGEN PRODUCTION IN POSTMENOPAUSAL WOMEN (1973)

Departments of Obstetrics, Gynecology and Biochemistry, University of Texas Southwestern Medical School at Dallas, Texas 75235
Responses of human, monkey and dog coronary arteries <i>in vitro</i> to carbocyclic thromboxane A<sub>2</sub> and vasodilators (1984)

Carbocyclic thromboxane A 2 (cTxA 2 ), a stable analogue of TxA 2 , and prostaglandin (PG) F 2α contracted helical strips of human, monkey and dog coronary arteries in a concentration‐dependent manner. Apparent ED 50 values for cTxA 2 were markedly less (1/58 in humans, 1/373 in monkeys and 1/397 in dogs) than those for PGF 2α ; maximum contractions induced by cTxA 2 and PGF 2α relative to those induced by 30 m M K + were approximately identical in the human and monkey arteries. PGI 2 caused a concentration‐related relaxation in human and dog coronary arteries maximally precontracted with cTxA 2 and in human, monkey and dog coronary arteries partially precontracted with PGF 2α . The relaxation response was greatest in the dog arteries and least in the monkey arteries. Contractions induced by cTxA 2 or PGF 2α and relaxations induced by PGI 2 were selectively antagonized by treatment with diphloretin phosphate. Human coronary artery strips contracted with cTxA 2 responded to nitroglycerine with a rapid, transient relaxation and to verapamil with a slowly‐developing, persistent relaxation, as did monkey and dog coronary artery strips. Thromboxane (Tx) A 2 appears to be one of the most potent endogenous vasoconstrictors in human coronary arteries, if cTxA 2 acts on TxA 2 receptors. It is suggested that PGI 2 , nitroglycerine and verapamil are effective vasodilators in human conduit coronary arteries maximally contracted with cTxA 2 , although the extent and the duration of vasodilatation induced by these agents were quite different.
System Closure in Integrated Newsprint Mills: Review of R&D Issues (1999)

Le fonctionnnement en circuit ferme des usines de papier journal integrees devrait se faire progressivement, afin de permetttre d'en evaluer les effets sur les activies des pâtes et papiers. Des simulations par ordinateur, ansi que l'analyse et l'optimisation des reseaux de distribution d'eau, sont essentielles pour l'elaboration et la mise en application de scenarios possibles pour le fonctionnement en circuit ferme. Des technologies d'extraction des contaminants internes et externes a l'usine sont requises afin de reduire la teneur en contaminants de l'eau blanche. De nouvelles techniques d'analyse devront etre mises au point afin de faciliter la selection des methodes a employer pour reduire la consommation d'eau douce. II faut des techniques ameliorees de commande non lineaire, afin d'ameliorer performance dynamique des proccessus integres.
A dual enzyme system composed of a polyester hydrolase and a carboxylesterase enhances the biocatalytic degradation of polyethylene terephthalate films (2016)

TfCut2 from Thermobifida fusca KW3 and the metagenome-derived LC-cutinase are bacterial polyester hydrolases capable of efficiently degrading polyethylene terephthalate (PET) films. Since the enzymatic PET hydrolysis is inhibited by the degradation intermediate mono-(2-hydroxyethyl) terephthalate (MHET), a dual enzyme system consisting of a polyester hydrolase and the immobilized carboxylesterase TfCa from Thermobifida fusca KW3 was employed for the hydrolysis of PET films at 60°C. HPLC analysis of the reaction products obtained after 24 h of hydrolysis showed an increased amount of soluble products with a lower proportion of MHET in the presence of the immobilized TfCa. The results indicated a continuous hydrolysis of the inhibitory MHET by the immobilized TfCa and demonstrated its advantage as a second biocatalyst in combination with a polyester hydrolase for an efficient degradation oft PET films. The dual enzyme system with LC-cutinase produced a 2.4-fold higher amount of degradation products compared to TfCut2 after a reaction time of 24 h confirming the superior activity of his polyester hydrolase against PET films.
Poly(Butylene Terephthalate) (2004)

This chapter contains sections titled: Introduction Polymerization of PBT Properties of PBT PBT Polymer Blends Flame-retardant Additives PBT and Water Conclusions References
Diagnosis of acute and chronic cardiac rejection by magnetic resonance imaging: a non-invasive in-vivo study. (1988)

To evaluate the potential usefulness for characterization of tissue and anatomical changes associated with cardiac transplantation rejection by nuclear magnetic resonance imaging (MRI), sixteen dogs underwent heterotropic cardiac transplantation with six not immunosuppressed serving as controls. Myocardial biopsy and MRI were obtained and compared on a weekly basis. Untreated allografts showed a significant increase in T2 and intensity values by MRI compared to the native heart as early as one week after transplantation. The MRI findings corresponded to the histological progression of acute rejection process in both treated and untreated groups. The linear relationship between histology and MRI was 0.72 while the correlation between T2 and the water content was 0.92. Serial gated MRI correlated with chronic anatomical changes of transplant rejection with evidence of progressive or increasing myocardial wall thickness and decrease in ventricular chamber size.