gebhart/patrepeval huggingface dataset:
Selective recoupling and stochastic dynamical decoupling (2006)

An embedded selective recoupling method is proposed which is based on the idea of embedding the recently proposed deterministic selective recoupling scheme of Yamaguchi et al. into a stochastic dynamical decoupling method, such as the recently proposed Pauli-random-error-correction scheme. The recoupling scheme enables the implementation of elementary quantum gates in a quantum information processor by partial suppression of the unwanted interactions. The random dynamical decoupling method cancels a significant part of the residual interactions. Thus the time scale of reliable quantum computation is increased significantly. Numerical simulations are presented for a conditional two-qubit swap gate and for a complex iterative quantum algorithm.
New CO/sub 2/ sensor with high resolution and fast response (2005)

The most common principles for CO/sub 2/ sensors are only partially fulfilling the requirements of cardiovascular and respiratory applications. A new acoustic sensor principle is claimed to be favorable in several respects, such as size, resolution, response time, reliability and cost. The sensor makes use of an electro acoustic element coupled to a Kundt resonator. The resonance frequency is determined by the mean molecular mass of the gas contained in the resonator, which may, in turn, be dominated by the variations of CO/sub 2/ concentration. A phased locked loop (PLL) oscillator provides both voltage and frequency outputs of the sensor. In this paper, a prototype design is presented, along with experimental results demonstrating that resolution, linearity and response time adequate for biomedical applications may be achieved.
Einleitung (1982)

Eine kleine interessierte Öffentlichkeit hat jahrelang erhebliche Defizite hinsichtlich einer angemessenen öffentlichen Diskussion über den Gegenstand „Sicherheitspolitik und Militär“ wie eine weitgehend fehlende wissenschaftliche Bearbeitung dieser Thematik beklagt.1 Seit dem Winter 1979/80 ist nun ein erheblicher Wandel im Interesse von Öffentlichkeit und Wissenschaft festzustellen. Zum einen werden Fragen von äußerer Sicherheit und Militär in den Medien wie in der Bevölkerung zunehmend und engagiert diskutiert; zum anderen befassen sich vor allem auch die Sozialwissenschaften in letzter Zeit intensiver mit der Thematik, wie sich beispielsweise anhand der inhaltlichen Schwerpunktbildung von großen internationalen Kongressen ablesen läßt.
Semliki Forest virus-derived virus-like particles: characterization of their production and transduction pathways (2005)

A procedure for the mobilization of Semliki Forest virus (SFV)-derived replicons using virus-like particles (VLPs) has been recently proposed. VLPs were obtained from 293T cells co-expressing the vesicular stomatitis virus glycoprotein (VSV-G) and a modified SFV replicon. Advantages of SFV VLPs include improved safety with a lack of sequence homology between components and reducing the risk of recombination events that could lead to the formation of autonomous particles. Characterization of SFV VLPs reveals a discrepancy in their ability to infect cells reported to be permissive. Furthermore, it was noted that not all viral envelopes were able to promote VLP release equally from transfected cells. These observations encouraged the examination of the molecular mechanisms supporting the different steps of VLP assembly and transduction. The use of a VSV-G related pathway for VLP entry into target cells was demonstrated; it was also observed that an internal ribosome entry site may not be adapted to control transgene expression in all cells. Finally, the need for a membrane-binding domain to obtain a fully active SFV replication complex and VLP formation was documented.
Discovery of Damage Patterns in Fuel Cell and Earthquake Occurrence Patterns by Co-Occurring Cluster Mining (2014)

We have proposed a novel data mining method called co-occurring cluster mining (CCM) for mining patterns from a sequence of multidimensional event data. The CCM first generates cluster candidates and then test the candidates based on clustering in the data space as well as co-occurrence degree in the event sequence. In searching appropriate clusters associated with co-occurrence, the search space is reduced by obtaining a dendrogram from a hierarchical clustering as the clustering procedure. In this paper, we show the potential of CCM with following two applications: (1) damage patterns in fuel cell and (2) earthquake occurrence patterns. In the fuel cell application, given a sequence of acoustic emission events, which comprise of waveform signal data of damages to a fuel cell, the mechanical interactions between components of the fuel cell are inferred from the mined co-occurrence patterns. Similarly, in the application of earthquakes, the interactions between distant earthquakes are extracted as co-occurrence patterns from a hypocenter catalog.
Novel α-Glucosidase from <i>Aspergillus nidulans</i> with Strong Transglycosylation Activity (2002)

ABSTRACT Aspergillus nidulans possessed an α-glucosidase with strong transglycosylation activity. The enzyme, designated α-glucosidase B (AgdB), was purified and characterized. AgdB was a heterodimeric protein comprising 74- and 55-kDa subunits and catalyzed hydrolysis of maltose along with formation of isomaltose and panose. Approximately 50% of maltose was converted to isomaltose, panose, and other minor transglycosylation products by AgdB, even at low maltose concentrations. The agdB gene was cloned and sequenced. The gene comprised 3,055 bp, interrupted by three short introns, and encoded a polypeptide of 955 amino acids. The deduced amino acid sequence contained the chemically determined N-terminal and internal amino acid sequences of the 74- and 55-kDa subunits. This implies that AgdB is synthesized as a single polypeptide precursor. AgdB showed low but overall sequence homology to α-glucosidases of glycosyl hydrolase family 31. However, AgdB was phylogenetically distinct from any other α-glucosidases. We propose here that AgdB is a novel α-glucosidase with unusually strong transglycosylation activity.
Neuroprotective effect of Rhodiola rosea Linn against MPTP induced cognitive impairment and oxidative stress (2013)

The oxidative stress and related biochemical alteration by MPTP were attenuated by Rhodiola rosea treatment. However, further studies may be necessary to elucidate the precise mechanism to support the clinical use of a plant source as antiparkinsonism drug.
Analysis and Design of Modified Half-Bridge Series-Resonant Inverter With DC-Link Neutral-Point-Clamped Cell (2015)

In this paper, a modified half-bridge (HB) resonant inverter topology with a dc-link neutral-point-clamped cell is proposed. A pseudo asymmetrical voltage-cancellation PWM method and a control strategy are introduced. The proposed topology can maximize the inverter output power factor, and minimize variations in the switching frequency. In addition, most switches are clamped to half of the dc input voltage at turn-off, increasing the overall efficiency of the system for a wide load range. The efficiency of the proposed inverter is improved up to 7% at light-load conditions compared with that of the conventional HB inverter. Informative expressions for performance comparison between the proposed inverter and its counterpart are provided. In addition, the losses in the inverter primary components are analytically analyzed in detail. For validation, a 120-W prototype is implemented, and experimental results are presented.
Expression of ERα36 in gastric cancer samples and their matched normal tissues (2011)

Estrogen receptor α36 (ERα36) is believed to mediate membrane-initiated effects of estrogen signaling, and promote cell growth and resistance to tamoxifen treatment. However, few studies are available regarding ERα36 expression in gastric cancer. In the present study, we evaluated the expression of ERα36, as well as estrogen receptor α66 (ERα66), in gastric cancer and its correlation with clinicopathological parameters. Real-time polymerase chain reaction (PCR) was applied to detect the expression of ERα66 and ERα36 mRNA in 45 pairs of samples of gastric cancer tissues and matched normal tissues. The ΔΔCT method was used to evaluate the relative quantity of target mRNA expression. Among the 45 pairs of samples of gastric cancer tissues and matched normal tissues adjacent to the tumor, the ERα36 mRNA levels in normal tissues were significantly higher than those observed in gastric cancer tissues (p=0.040). Additionally, the expression of ERα66 mRNA levels between gastric cancer tissues and matched normal tissues had no statistically significant difference. We confirmed that ERα36 mRNA was expressed in the four gastric cancer cell lines, and ERα66 mRNA was expressed in two of the four gastric cancer cell lines. According to the tissue and cell findings, it was suggested that the expression level of ERα36 is greater than that of ERα66 in gastric cancer. In conclusion, the expression of ERα66 and ERα36 in gastric cancer tissues and cells was confirmed in this study. A decreased expression of ERα36 mRNA in gastric cancer tissues may be one of the factors affecting tumorigenesis in gastric cancer patients.
Direct current conductivity detection in ion chromatography (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDirect current conductivity detection in ion chromatographyDayong. Qi, Tetsuo. Okada, and Purnendu K. DasguptaCite this: Anal. Chem. 1989, 61, 13, 1383–1387Publication Date (Print):July 1, 1989Publication History Published online1 May 2002Published inissue 1 July 1989https://pubs.acs.org/doi/10.1021/ac00188a015https://doi.org/10.1021/ac00188a015research-articleACS PublicationsRequest reuse permissionsArticle Views258Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Architecture for CORDIC algorithm realization without ROM lookup tables (2003)

This paper proposes an architecture for implementing the CORDIC algorithm. By decomposing an arbitrary rotation angle into a sequence of coarse angles (the tangent value of each of which is a power of 2) and a fine angle which is small enough, this architecture can be implemented by performing a sequence of shift-and-add operations in the radix-2 system without any ROM lookup table or real multiplication requirement. It is suitable to be designed in a pipelined architecture for performing high-speed operations.
Solid‐State NMR (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Active self-interference cancellation of passband signals using gradient descent (2013)

Recent interest in same-frequency/same-time full-duplex radio frequency communication has led to the study of self-interference cancellation methods for a co-located transmitter and receiver pair. So far, important practical aspects of self-interference cancellation have not been considered, such as receiver amplifier saturation and dynamic range, which extend the minimum distance between transmit and receive antennas without sufficient interference isolation. Further, current solutions lack significant self-interference attenuation for wideband signals. In this paper, a method for canceling a passband self-interference signal using adaptive filtering in the digital domain is presented. Based on acoustic active noise cancellation foundations, a cancellation signal is created that destructively combines with the undesired self-interference signal in the passband, taking into account differences in the complex passband nature of RF signals versus the baseband nature of acoustic signals. The efficacy of this interference cancellation scheme is compared to other self-interference cancellation architectures in the literature including digital as well as other active passband approaches. It is shown that for high-power wideband transmission signals, this adaptive active analog cancellation method effectively reduces the self-interference signal while satisfying practical constraints set by transceiver hardware. It is also shown that this approach decreases the minimum distance between the transmit and receive antennas or allows higher transmission power, thereby extending the range of a full-duplex device.
Multigram synthesis of 1‐alkylamido phospholipids (1993)

Phospholipids containing a 1-alkylamido linkage have shown promising in vitro neoplastic cell growth inhibitory properties and anti-human immunodeficiency viral activity. We have synthesized a series of alkylamido ether lipid analogues on a milligram scale for initial evaluation, but for further in vivo testing of these bioactive phospholipids, synthesis on a larger scale is required. The multigram synthesis of 1-alkylamido ether phospholipids was accomplished by modifying reaction conditions in the amidation step and changing reagents and solvent systems in both the detritylation and phosphorylation steps. This was most crucial in the phosphorylation step, where in the multigram synthesis 2-bromoethyl dichlorophosphate in diethyl ether/tetrahydrofuran (7:3, vol/vol) gave much improved yields as compared to the 2-chloro-2-oxo-1,3,2-dioxaphospholane reagent. The modifications also resulted in a product that could be more easily purified in sufficient quantities for use in in vivo inhibition studies.
Photonic lanterns: a study of light propagation in multimode to single-mode converters (2010)

The "photonic lantern," an optical fibre device that has emerged from the field of astrophotonics, allows for a single-mode photonic function to take place within a multimode fibre. We study and evaluate the modal behaviour of photonic lanterns as well as the conditions for achieving low-loss between a multimode fibre and a "near-diffraction limited" single-mode system. We also present an intuitive analogy of the modal electromagnetic propagation behaviour along the photonic lantern transition in terms of the Kronig-Penney model in Quantum Mechanics.
Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells. (1988)

Cultured arterial smooth muscle cells (SMC) can produce platelet-derived growth factor (PDGF)-like molecules. This property raises the possibility that SMC-derived PDGFs function as autocrine/paracrine regulators in the formation and maintenance of the artery wall. In this study we have asked if levels of mRNAs directing synthesis of PDGF are modulated in aortic SMC during postnatal development. We report here that genes encoding PDGF A- and B-chain precursors are expressed at similar low levels in intact aortas from newborn and adult rats. Marked differences in regulation of transcript abundance of these genes were revealed when aortic SMC were grown in cell culture. PDGF B-chain transcripts accumulated in passaged newborn rat SMC but not adult rat SMC, whereas PDGF A-chain RNA was found in comparable amounts in SMC from both age groups. Similarly, SMC from newborn rats secreted at least 60-fold more PDGF-like activity into conditioned medium than did adult rat SMC. PDGF B-chain transcripts in newborn rat aortic SMC are short-lived and increased 5-fold by 3 hr after treatment with cycloheximide. In contrast, PDGF A-chain transcripts are more stable, and their constitutive levels were generally unaffected by cycloheximide. These results show that PDGF A- and B-chain genes are transcribed in the normal rat aorta and provide evidence for age-related change in the control of PDGF B-chain gene expression in aortic SMC. Independent regulation of transcript levels in cultured SMC leaves open the possibility that PDGFs of different composition (AA, AB, BB) play different roles in normal function of the artery wall.
Metal-assisted Assembly and Stabilization of Collagen-like Triple Helices (2004)

Single-chain and TRIS-assembled collagen mimetic peptide structures incorporating catechol groups were synthesized. When 1/3 equiv of Fe3+ was added to the single-chain compound in 50 mM CAPS buffer (pH 10), the 1:3 Fe3+-catechol complex that formed acted as an N-terminal scaffold to assemble the triple helix. When 1 equiv of Fe3+ was added to the TRIS-assembled compound in the buffer solution, the Fe3+-catechol complex acted as an extra C-terminal scaffold, which lead to a triple helix with both termini tethered. The formation of this C-terminal complex increased the Tm by a remarkable 22 degrees C!
The Effect of Perfluoropropane on the Cornea in Rabbits and Cats (1987)

The effects of perfluoropropane gas on the cornea were compared with those of sulfur hexafluoride gas following injection into the anterior chamber of rabbits and cats. Injection of 0.15 mL of gas produced a perfluoropropane bubble that lasted 22 days compared with a sulfur hexafluoride bubble that lasted seven days. The sulfur hexafluoride bubble produced corneal edema for as long as the gas was present. With perfluoropropane, corneal edema persisted even after the gas bubble disappeared. In another group of cats, multiple sequential injections of sulfur hexafluoride to maintain a gas bubble of duration comparable with the perfluoropropane bubble also produced edema as long as gas was present. Clinical corneal edema, endothelial fibrin deposition, endothelial opacities, and retrocorneal membrane were observed by slit-lamp and light, scanning, and transmission electron microscopic examinations of the corneas exposed to perfluoropropane but not of those exposed to sulfur hexafluoride. Prolonged corneal endothelial contact by perfluoropropane results in corneal edema due to endothelial dysfunction, which persists in cats probably because feline endothelium is less capable of regeneration than that of rabbit.
Enantiospecific total synthesis of pseudopterosins A and E (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnantiospecific total synthesis of pseudopterosins A and EE. J. Corey and Philip CarpinoCite this: J. Am. Chem. Soc. 1989, 111, 14, 5472–5474Publication Date (Print):July 1, 1989Publication History Published online1 May 2002Published inissue 1 July 1989https://pubs.acs.org/doi/10.1021/ja00196a067https://doi.org/10.1021/ja00196a067research-articleACS PublicationsRequest reuse permissionsArticle Views1646Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Characterization of the Total Free Radical Scavenger Capacity of Vegetable Oils and Oil Fractions Using 2,2-Diphenyl-1-picrylhydrazyl Radical (2000)

The total free radical scavenger capacity (RSC) of 57 edible oils from different sources was studied: olive (24 brands of oils), sunflower (6), safflower (2), rapeseed (3), soybean (3), linseed (2), corn (3), hazelnut (2), walnut (2), sesame (2), almond (2), mixture of oils for salad (2), "dietetic" oil (2), and peanut (2). Olive oils were also studied according to their geographical origins (France, Greece, Italy, Morocco, Spain, and Turkey). RSC was determined spectrophotometrically by measuring the disappearance of the radical 2,2-diphenyl-1-picrylhydrazyl radical (DPPH(*)) at 515 nm. The disappearance of the radical followed a double-exponential equation in the presence of oils and oil fractions, which suggested the presence of two (fast and slow) groups of antioxidants. RSC was studied for the methanol-soluble phase ("methanolic fraction", MF) of the oil, the fraction nonsoluble in methanol ("lipidic fraction", LF), and the nonfractionated oil ("total oil"; TF = MF + LF). Only olive, linseed, rapeseed, safflower, sesame, and walnut oils showed significant RSC in the MF due to the presence of phenolic compounds. No significant differences were found in the RSC of olive oils from different geographical origins. Upon heating at 180 degrees C the apparent constant for the disappearance of RSC (k(T)) and the half-life (t1/2) of RSC for MF, LF, and TF were calculated. The second-order rate constants (k2) for the antiradical activity of some phenolic compounds present in oils are also reported.
Anomalous Negative Fluorescence Anisotropy in Yellow Fluorescent Protein (YFP 10C):  Quantitative Analysis of FRET in YFP Dimers (2007)

Yellow fluorescent protein (YFP) is widely used as a genetically encoded fluorescent marker in biology. In the course of a comprehensive study of this protein, we observed an unusual, negative fluorescence anisotropy at pH 6.0 (McAnaney, T. B., Zeng, W., Doe, C. F. E., Bhanji, N., Wakelin, S., Pearson, D. S., Abbyad, P., Shi, X., Boxer, S. G., and Bagshaw, C. R. (2005) Biochemistry 44, 5510-5524). Here we report that the fluorescence anisotropy of YFP 10C depends on protein concentration in the low micromolar range that was not expected. We propose that the negative anisotropy is a result of unidirectional Förster resonance energy transfer (FRET) in a dimer of YFP, with the donor chromophore in the neutral form and the acceptor chromophore in the anionic form. This unusual mechanism is supported by studies of a monomeric YFP (A206K YFP) and transient-absorption spectroscopy of YFP 10C. A detailed analysis of the chromophore transition dipole moment direction is presented. The anisotropy and rate constant of this energy transfer are consistent with values produced by an analysis of the dimer structure observed in crystals.