gebhart/patrepeval huggingface dataset:
A novel approach for voltage collapse analysis and control (2002)

This paper presents a systematic approach for power system voltage stability assessment and control. Unlike the conventional two-step procedure, it simultaneously solves the system differential and the algebraic equations at steady state to obtain the equilibrium solution, thereby removing all the unrealistic assumptions of slack and PV buses. Combined with a parameterized continuation technique, the methodology first identifies the system voltage collapse point during the direct equilibrium tracing, without rebuilding the system dynamic Jacobian and checking its singularity. Then, the voltage stability margin sensitivity is utilized to design an effective control strategy to mitigate voltage collapse. The detected voltage collapse point is proven being associated with a saddle node bifurcation in the rigorous sense of small-disturbance stability. The generator field and armature current limits are also accurately handled. Numerical test results with the New-England 39-bus system are presented to demonstrate the approach.
Identification and Fine Mapping of Nuclear and Nucleolar Localization Signals within the Human Ribosomal Protein S17 (2015)

Human ribosomal protein S17 (RPS17) is mutated in Diamond-Blackfan Anemia (DBA), a bone marrow disorder that fails to produce sufficient red blood cells leading to anemia. Recently, an RPS17 protein sequence was also found to be naturally inserted in the genome of hepatitis E virus (HEV) from patients chronically-infected by HEV. The role of RPS17 in HEV replication and pathogenesis remains unknown due to the lack of knowledge about how RPS17 functions at a molecular level. Understanding the biological function of RPS17 is critical for elucidating its role in virus infection and DBA disease processes. In this study we probed the subcellular distribution of normal and mutant RPS17 proteins in a human liver cell line (Huh7). RPS17 was primarily detected within the nucleus, and more specifically within the nucleoli. Using a transient expression system in which RPS17 or truncations were expressed as fusions with enhanced yellow fluorescent protein (eYFP), we were able to identify and map, for the first time, two separate nuclear localization signals (NLSs), one to the first 13 amino acids of the amino-terminus of RPS17 and the other within amino acids 30-60. Additionally, we mapped amino acid sequences required for nucleolar accumulation of RPS17 to amino acids 60-70. Amino acids 60-70 possess a di-RG motif that may be necessary for nucleolar retention of RPS17. The results from this study enhance our knowledge of RSP17 and will facilitate future mechanistic studies about the roles of RSP17 in hepatitis E and DBA disease processes.
MicroRNA Signature Helps Distinguish Early from Late Biochemical Failure in Prostate Cancer (2013)

miRNAs can help to predict biochemical failure risk at the time of prostatectomy.
Electrical Vehicle Stopper Evaluation, Phase III Jaycor (2000)

Abstract : This report discusses the results of the Electrical Vehicle Stopper Evaluation (EVSE) program phase III evaluation of the Jaycor Auto Arrestor vehicle stopper device. The Auto Arrestor directly injects a large current pulse into the underside of the vehicle and stops the vehicle by damaging the electrical components. This report also discusses the field evaluation of sa&ty, ease of use, and effectiveness of the device.
Absence of toll-Like Receptor 4 (TLR4) Signaling in the Donor Organ Reduces Ischemia and Reperfusion Injury in a Murine Liver Transplantation Model (2007)

This study analyzes how toll-like receptor 4 (TLR4) signaling in the donor organ affects the ischemia and reperfusion injury (IRI) sequel following liver transplantation. Isogenic orthotopic liver transplantations (OLTs) with rearterialization were performed in groups of wild-type (WT) and TLR4 knockout (KO) mice after donor liver preservation in University of Wisconsin solution at 4 degrees C for 24 hours. Unlike WT OLTs, TLR4-deficient OLTs transplanted to either WT or TLR4 KO recipients suffered significantly less hepatocellular damage, as evidenced by serum alanine aminotransferase levels, and histological Suzuki's grading of liver IRI. Disruption of TLR4 signaling in OLTs decreased local neutrophil sequestration, CD4+ T cell infiltration, interferon (IFN)-gamma-inducible protein 10 (CXCL10) and an intercellular adhesion molecule (ICAM-1), as well as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-2, and IFN-gamma, yet increased IL-4 and IL-10 expression. The well-functioning OLTs from TLR4 KO donors revealed attenuated activity of capase-3, and enhanced heme oygenase-1 (HO-1) expression, along with decreased levels of apoptotic endothelial cells/hepatocytes, as compared with WT OLTs with intact TLR4 signaling. Thus, the functional sentinel TLR4 complex in the donor organ plays a key role in the mechanism of hepatic IRI after OLT. Disruption of TLR4 pathway downregulated the early proinflammatory responses and ameliorated hepatic IRI. These results provide the rationale to locally modify innate TLR4 signaling in the donor organ to more efficiently control the adaptive posttransplantation IRI-dependent responses.
Development of High Strength Microcellular Foams Using Polyether Block Amide (2010)

This report presents a successful development of batch foaming techniques of the engineering elastomer. The polyether block amide (PEBAX) was investigated as an engineering elastomer by using batch foaming techniques. The Pebax provide a unique combination of mechanical and chemical properties. Understanding the effect of the different parameter in batch foaming process allows obtaining the high quality foamed product of the engineering elastomer.\nTemperature has been considered as an important parameter in the batch foaming process. It was shown that the density of foamed product was decreasing by the temperature increasing under its melting temperature. Both temperature and pressure have to reach the minimum requirement to obtain the fine foamed product. As an experiment result, it indicates that there is an optimal portfolio of foaming parameter for the different Pebax resin.
Bioabsorbable Fibers of <i>p</i>-Dioxanone Copolymers (1990)

Growing interest in synthetic, absorbable copolymers and their use in the production of fibers, including sutures, and drug delivery systems has been addressed in the patent and technical literature over the past fifteen years1-11 However, most investigators have focused their attention on copolymers which are derived primarily from ∝-hydroxy acids 3-6, anhydrides7,8 or oxalate esters9-11. The preparation of high molecular weight poly(p-dioxanone)12, a polyether-ester, and its conversion to a useful absorbable suture with unique properties has now led to the interest in exploring the potential of poly(p-dioxanone) containing other comonomeric units in the chain.13,14. Hence, the studies which form the basis of this report were conducted to determine the effect of incorporating different quantities of giycolyl moieties into the poly(p-dioxanone) chains on the physical and biological properties of drawn monofilaments. EXPERIMENTAL Materials and Major Characterization Methods. Polymerization grade p-dioxanone and glycolide monomers were obtained as described in early reports 3,12.
Evaluation of an electrochemical sensor for measuring blood ketones. (2000)

This ketone sensor accurately measures whole blood beta-HBA concentrations within 30 s.
Adaptive techniques for lossless data compression (2001)

Data compression techniques have many applications in medical signal and image processing. In medical imaging, lossless image compression is required. According to information theory, a fundamental problem in data compression is to estimate the probability distribution function (pdf) of the signal given the data seen so far. The estimation should be as close as possible to the true pdf. For non-stationary signals, an adaptive estimation technique must be used. In this paper we address this problem by reviewing the current practices in compressing digital image and audio data. We show that the popular prediction plus entropy coding approach is only a rough approximation to that suggested by information theory. We then discuss a Bayesian approach to improve the prediction performance. We also propose another Bayesian approach for adaptive pdf estimation.
Small Molecules Can Selectively Inhibit Ephrin Binding to the EphA4 and EphA2 Receptors (2008)

The erythropoietin-producing hepatocellular (Eph) family of receptor tyrosine kinases regulates a multitude of physiological and pathological processes. Despite the numerous possible research and therapeutic applications of agents capable of modulating Eph receptor function, no small molecule inhibitors targeting the extracellular domain of these receptors have been identified. We have performed a high throughput screen to search for small molecules that inhibit ligand binding to the extracellular domain of the EphA4 receptor. This yielded a 2,5-dimethylpyrrolyl benzoic acid derivative able to inhibit the interaction of EphA4 with a peptide ligand as well as the natural ephrin ligands. Evaluation of a series of analogs identified an isomer with similar inhibitory properties and other less potent compounds. The two isomeric compounds act as competitive inhibitors, suggesting that they target the high affinity ligand-binding pocket of EphA4 and inhibit ephrin-A5 binding to EphA4 with K(i) values of 7 and 9 mum in enzyme-linked immunosorbent assays. Interestingly, despite the ability of each ephrin ligand to promiscuously bind many Eph receptors, the two compounds selectively target EphA4 and the closely related EphA2 receptor. The compounds also inhibit ephrin-induced phosphorylation of EphA4 and EphA2 in cells, without affecting cell viability or the phosphorylation of other receptor tyrosine kinases. Furthermore, the compounds inhibit EphA4-mediated growth cone collapse in retinal explants and EphA2-dependent retraction of the cell periphery in prostate cancer cells. These data demonstrate that the Eph receptor-ephrin interface can be targeted by inhibitory small molecules and suggest that the two compounds identified will be useful to discriminate the activities of EphA4 and EphA2 from those of other co-expressed Eph receptors that are activated by the same ephrin ligands. Furthermore, the newly identified inhibitors represent possible leads for the development of therapies to treat pathologies in which EphA4 and EphA2 are involved, including nerve injuries and cancer.
A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer’s disease (2000)

The reduced or absent risk for AD conferred by APOE in older populations has been well reported in the literature, prompting the suggestion that additional genetic risk factors confer risk for later-onset AD. In the author's dataset the opposite effects of APOE and CST3 genotype on risk for AD with increasing age suggest that CST3 is one of the risk factors for later-onset AD. Although the functional significance of this coding polymorphism has not yet been reported, several hypotheses can be proposed as to how variation in an amyloidogenic cysteine protease inhibitor may have pathologic consequences for AD.
Early Spray Development in Gasoline Direct-Injected Spark Ignition Engines (1998)

<div class="htmlview paragraph">The characteristics of the early development of fuel sprays from pressure swirl atomizer injectors of the type used in direct injection gasoline engines is investigated. Planar laser-induced fluorescence (PLIF) was used to visualize the fuel distribution inside a firing optical engine.</div> <div class="htmlview paragraph">The early spray development of three different injectors at three different fuel pressures (3, 5, and 7 MPa) was followed as a function of time in 30 μsec intervals. Four phases could be identified: 1) A <i>delay phase</i> between the rising edge of the injection pulse and the first occurrence of fuel in the combustion chamber, 2) A <i>solid jet</i> or pre-spray phase, in which a poorly atomized stream of liquid fuel during the first 150 μsec of the injection. 3) A <i>wide hollow cone</i> phase, separation of the liquid jet into a hollow cone spray once sufficient tangential velocity has been established and 4) A <i>fully developed</i> spray, in which the spray cone angle is narrowed due to a low pressure zone at the center.</div> <div class="htmlview paragraph">The spray penetration, quality of atomization and the specific fuel distribution during the duration of injection (about 2 ms or 12 CAD) are functions of fuel delivery pressure as well as ambient pressure. The experiments are intended for future comparison with computational results, as well as for guidance in the the design of GDI combustion systems.</div>
Viable prosthetic interface (1971)

Abstract The ability to produce a viable bond at the interface of living tissue and inert polymeric materials has been tested in three different contaminated environments. The prosthetic implants, consisting of nylon 66 velour and polyurethane, were tested in the intestinal wall of rabbits, the urinary bladder of dogs, and the skin of rats. The small (1.5 × 2.0 cm) velour implants had a tendency to slough in the intestinal wall while a tubular prosthesis (6 × 3 cm) and a large patch (4.5 × 3.0 cm) were of varying success. Utilization of the prosthesis to replace 25% of the urinary bladder wall was successful for as long as 7 months, at which time postmortem examination of the animals revealed no anastomotic leaks or calculi formation. Replacement of 20 or 40% of the rats burned and infected skin resulted in less than a 10% mortality. Furthermore, histologic studies of all successful prostheses revealed a prompt enmeshing of the velour filaments with fibrin followed at 3‐4 days with an ingrowth of fibroblasts, capillaries, and a few foreign body giant cells. Maturation of the wound resulted in a dense, mature collagen matrix. Removal of the prosthesis at this time occurred only by the disruption of the sub‐prosthetic tissue.
Effective surface passivation of crystalline silicon using ultrathin Al<sub>2</sub>O<sub>3</sub> films and Al<sub>2</sub>O<sub>3</sub>/SiN<i><sub>x</sub></i> stacks (2009)

Abstract We measure surface recombination velocities (SRVs) below 10 cm/s on p‐type crystalline silicon wafers passivated by atomic–layer–deposited (ALD) aluminium oxide (Al 2 O 3 ) films of thickness ≥10 nm. For films thinner than 10 nm the SRV increases with decreasing Al 2 O 3 thickness. For ultrathin Al 2 O 3 layers of 3.6 nm we still attain a SRV < 22 cm/s on 1.5 Ω cm p‐Si and an exceptionally low SRV of 1.8 cm/s on high‐resistivity (200 Ω cm) p‐Si. Ultrathin Al 2 O 3 films are particularly relevant for the implementation into solar cells, as the deposition rate of the ALD process is extremely low compared to the frequently used plasma‐enhanced chemical vapour deposition of silicon nitride (SiN x ). Our experiments on silicon wafers passivated with stacks composed of ultrathin Al 2 O 3 and SiN x show that a substantially improved thermal stability during high‐temperature firing at 830 °C is obtained for the Al 2 O 3 /SiN x stacks compared to the single‐layer Al 2 O 3 passivation. Al 2 O 3 /SiN x stacks are hence ideally suited for the implementation into industrial‐type silicon solar cells where the metal contacts are made by screen‐printing and high‐temperature firing of metal pastes. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
“My heart want to say something”: exploring ELL vocabulary use through e‐mail (2011)

Purpose The purpose of this paper is to report on one high school English‐language‐learner's (ELL) breadth and depth of vocabulary as he communicated with his teacher through e‐mail across geographic boundaries for over 18 months. Design/methodology/approach The authors began by separating 358 e‐mails into three time periods (first beginning, second middle, and third end) to calculate breadth using lexical density (type‐token ratios). Then, we sampled e‐mails based on personal and impersonal topics within these time periods and linguistically analyzed them for lexical cohesion, semantic usage, and derivational morphology. Interviews with participants before and after the analysis served as member checks. Findings The quantitative results showed a steady improvement in the breadth of the student's vocabulary over time. Qualitative analyses revealed four major uses of vocabulary within the context of e‐mail and the teacher‐student relationship. Practical implications Given our findings, we offer educators insights into ELL strategies and vocabulary assessment, not only with e‐mail but in all written communication. Social implications A social writing tool like e‐mail can be useful for learning English in a safe, non‐threatening environment. Moreover, a trusting social relationship between communicators that develops over time can expedite the language learning process. Originality/value Very few studies have looked at the strategic ways ELL students use vocabulary to learn English through e‐mailing.
7-Deaza-2′-deoxyadenosine and 3-deaza-2′-deoxyadenosine replacing dA within d(A<sub>6</sub>)-tracts: differential bending at 3′-and 5′-junctions of d(A<sub>6</sub>) d(T<sub>6</sub>) and B-DNA (1992)

7-Deaza-2'-deoxyadenosine (1, c7Ad) and 3-deaza-2'-deoxyadenosine (2, c3Ad) have been incorporated into d(AAAAAA) tracts replacing dA at various positions within oligonucleotides. For this purpose suitably protected phosphonates have been prepared and oligonucleotides were synthesized on solid-phase. The oligomers were hybridized with their cognate strands. The duplexes were phosphorylated at OH-5' by polynucleotide kinase and self-ligated to multimers employing T4 DNA ligase. Oligomerized DNA-fragments were analyzed by polyacrylamide gel electrophoresis and the bending was determined from anomalies of electrophoretic mobility. Replacement of dA by c3Ad decreased the bending more than replacement by c7Ad. Reduction of bending was much stronger when the modified nucleosides replaced one or several dA residues at the 3'-site of an d(AAAAAA)-tract whereas replacement at the 5'-site showed no significant influence [1, 2].
An improved recording gage for blowing snow (1975)

With the experience gained from an earlier gage (Tabler and Jairell, 1971), significant innovations have greatly improved the operation of a simple, inexpensive instrument for recording blowing snow. The most important improvement is the efficient turntable design which allows the precipitation gage to be independent of the snow trap, the result being a high‐quality chart record. Principal advantages include simplicity, inexpensiveness, and suitability for operation in remote areas lacking electrical power. The relationship of snow caught by this gage to snow accumulation behind a snow fence should be studied further as a means of calibration. It appears that the gage can be used to estimate total snow transport during drifting events.
Vasomotor Symptoms and Insulin Resistance in the Study of Women's Health Across the Nation (2012)

Hot flashes were associated with a higher HOMA index, an estimate of insulin resistance, and to a lesser extent higher glucose. Metabolic factors may be relevant to understanding the link between hot flashes and cardiovascular disease risk.
Autonomous Control of Inspired Oxygen Concentration During Mechanical Ventilation of the Critically Injured Trauma Patient (2009)

Autonomous control of FIO2 offers the opportunity for a reduction in oxygen usage, allowing a weight and resource reduction, without increasing risk of hypoxemia in ventilated trauma patients.
THE DETECTION AND DETERMINATION OF ETHYL AND METHYL ALCOHOLS IN MIXTURES BY THE IMMERSION REFRACTOMETER. (1905)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE DETECTION AND DETERMINATION OF ETHYL AND METHYL ALCOHOLS IN MIXTURES BY THE IMMERSION REFRACTOMETER.Albert E. Leach and Hermann C. LythgoeCite this: J. Am. Chem. Soc. 1905, 27, 8, 964–972Publication Date (Print):August 1, 1905Publication History Published online1 May 2002Published inissue 1 August 1905https://pubs.acs.org/doi/10.1021/ja01986a005https://doi.org/10.1021/ja01986a005research-articleACS PublicationsRequest reuse permissionsArticle Views60Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Technique for visualization and perfusion of bronchial arteries: Suggested clinical and diagnostic applications (1963)

A NEW AP-T proach to therapy for carcinoma of the lung.Once the lesion has extended beyond the stage for which surgery or irradiation are &ecthe, there is no satisfactory method of treatment.Nitrogen mustard (HNZ) is effective in oat (-ell and some anaplastic carcinomas, but other general chemotherapeutic agents have not been effective.With the present interest in regional perfusion, it is logical to seek a means of perfusing the lungs.Pierpont and Blades11 attempted regional perfusion of a single lung via the pulmonary artery.Two techniques were used: one, isolating the pulmonary artery and injecting the agent directly ancl the other, using an occlusive, balloon-tipped catheter in the pulmonary artery.The results were not encouraging.This should not be unexpected since the major blood supply to lung tissues
A study on the semantic relatedness of query and document terms in information retrieval (2009)

The use of lexical semantic knowledge in information retrieval has been a field of active study for a long time. Collaborative knowledge bases like Wikipedia and Wiktionary, which have been applied in computational methods only recently, offer new possibilities to enhance information retrieval. In order to find the most beneficial way to employ these resources, we analyze the lexical semantic relations that hold among query and document terms and compare how these relations are represented by a measure for semantic relatedness. We explore the potential of different indicators of document relevance that are based on semantic relatedness and compare the characteristics and performance of the knowledge bases Wikipedia, Wiktionary and WordNet.
Automatic unloading of heavy sacks from containers (2008)

Automated unloading of mass goods is of great importance for cost-effective logistic processes. Furthermore, companies are interested in promoting the automation of their logistic processes. In this paper the unloading of heavy, inflexible sacks from containers is addressed. The sacks are stacked neatly in rows of piles. Our approach combines object recognition and object handling while taking their dependencies into account. For 3D scene data acquisition a 2D laser scanner, which is mounted on a pitch device, is employed. The object recognition segments the acquired data by taking advantage of the sack surface characteristics. For sack handling a gripper consisting of a system with extendable and fixed claws is presented. Our system is the result of a feasibility study showing that sacks which are heavy and resistant to bending sacks can be handled automatically. Therefore further research is necessary to build a prototype system.