gebhart/patrepeval huggingface dataset:
Gesture recognition using kinect for sign language translation (2013)

Sign Language is a widely used method of communication among the community of deaf-mute people. It contains some series of body gestures, which enables a person to interact without the need of spoken words. Although the use of sign language is very popular among the deaf-mute people but the other communities don't even try to learn it, this creates a gulf of communication and hence becomes a cause of the isolation of physically impaired people. The problem creates a requirement of a system which can facilitate a way of communication between these two communities. This paper presents a novel method for identification of an isolated sign language gesture using Microsoft Kinect. This paper presents the way of extracting some highly robust features from the depth image provided by Kinect and to use them in creating a robust and accurate gesture recognition system, for the purpose of sign language translation. Apart from translation, the proposed system also opens the doors of endless applications in the field of Human Computer Interaction. The proposed algorithm helps in translating a sign language gesture performed by a user, which in-turn can be used as an input for different types of applications.
Growth inhibition of K562 cells by cyclin E gene-specific small interfering RNA. (2005)

RNA interference induces obvious inhibition of cyclin E gene expression, which consequently affects the proliferation of K562 cells.
p300 Protein as a Coactivator of GATA-5 in the Transcription of Cardiac-restricted Atrial Natriuretic Factor Gene (1999)

A cellular target of adenovirus E1A oncoprotein, p300 is a transcriptional coactivator and a negative regulator of cellular proliferation. A previous study suggests that the p300 family is also involved in cell type-specific transcription in cardiac myocytes. However, nothing is known about which cardiac transcription factor(s) interact with and transactivate through these proteins. The transcription factors GATA-4/5/6 have been implicated as key regulators of cardiogenesis, and they participate in the transcription of many cardiac-specific genes. Here we show that E1A represses the GATA-5-dependent transactivation of a promoter derived from the cardiac-restricted atrial natriuretic factor gene. This repression is correlated with the interaction of E1A with p300, indicating that p300 participates in GATA-5-dependent transactivation. E1A markedly down-regulates endogenous atrial natriuretic factor expression, as well as disrupts the interaction between p300 and GATA-5. A small fragment of p300 containing the carboxyl-terminal cysteine/histidine-rich domain, sufficient to interact with GATA-5, prevents transcriptional activation by GATA-5 as a dominant-negative mutant. Consistent with its role as a coactivator, p300 markedly potentiates GATA-5-activated transcription. These results implicate p300 as an important component of myocardial cell differentiation and provide an insight into the relationship between mechanisms that mediate cell type-specific transcription and cell cycle regulation during cardiogenesis.
Recovering intrinsic fluorescence by Monte Carlo modeling (2013)

We present a novel way to recover intrinsic fluorescence in turbid media based on Monte Carlo generated look-up tables and making use of a diffuse reflectance measurement taken at the same location. The method has been validated on various phantoms with known intrinsic fluorescence and is benchmarked against photon-migration methods. This new method combines more flexibility in the probe design with fast reconstruction and showed similar reconstruction accuracy as found in other reconstruction methods.
Pancreatic divisum with choledochal cyst and calculus: MR appearance. (2003)

Pancreatic divisum is the most common congenital anomaly of the pancreas but its association with choledochal cyst is extremely rare. We describe here a case of pancreatic divisum with choledochal cyst with a stone which was successfully treated at surgery. The common congenital pancreaticobiliary abnormalities are briefly discussed.
Human Immunodeficiency Virus Type 1 Subtype C Tat Fails To Induce Intracellular Calcium Flux and Induces Reduced Tumor Necrosis Factor Production from Monocytes (2007)

Over 50% of all human immunodeficiency virus type 1 (HIV-1) infections worldwide are caused by subtype C strains, yet most research to date focuses on subtype B, the subtype most commonly found in North America and Europe. The HIV-1 trans-acting regulatory protein (Tat) is essential for regulating productive replication of HIV-1. Tat is secreted by HIV-infected cells and alters several functions of uninfected bystander cells. One such function is that, by acting at the cell membrane, subtype B Tat stimulates the production of tumor necrosis factor (TNF) and chemokine (C-C motif) ligand 2 (CCL2) from human monocytes and can act as a chemoattractant. In this study, we show that the mutation of a cysteine to a serine at residue 31 of Tat commonly found in subtype C variants significantly inhibits the abilities of the protein to bind to chemokine (C-C motif) receptor 2 (CCR2), induce intracellular calcium flux, stimulate TNF and CCL2 production, and inhibit its chemoattractant properties. We also show that TNF is important in mediating some effects of extracellular Tat. This report therefore demonstrates the important functional differences between subtype C and subtype B Tat and highlights the need for further investigation into the different strains of HIV-1.
A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. (1992)

We devised an efficient genetic mapping system in the nematode Caenorhabditis elegans which is based upon the differences in number and location of the transposable element Tc1 between the Bristol and Bergerac strains. Using the nearly completed physical map of the C. elegans genome, we selected 40 widely distributed sites which contain a Tc1 element in the Bergerac strain, but not in the Bristol strain. For each site a polymerase chain reaction assay was designed that can distinguish between the Bergerac Tc1-containing site and the Bristol "empty" site. By combining appropriate assays in a single reaction, one can score multiple sites within single worms. This permits a mutation to be rapidly mapped, first to a linkage group and then to a chromosomal subregion, through analysis of only a small number of progeny from a single interstrain cross.
Systematic lossy forward error protection for video waveforms (2004)

A novel scheme for error-resilient digital video broadcasting, using Wyner-Ziv coding, is presented in this paper. We apply the general framework of systematic lossy source-channel coding to generate a supplementary bitstream that can correct transmission errors in the decoded video waveform up to a certain residual distortion. The systematic portion consists of a conventional MPEG-coded bitstream, which is transmitted over the error-prone channel without any forward error correction. The supplementary bitstream is a low rate representation of the transmitted video sequence generated using Wyner-Ziv encoding. We use the conventionally decoded error-concealed MPEG video sequence as side information to decode the Wyner-Ziv bits. The decoder combines the error-prone side information and the Wyner-Ziv description to yield an improved decoded video signal. We show how this scheme can be used to build a system which achieves graceful degradation without the need of a layered representation of the video waveform.
An extended cavity femtosecond Cr:LiSAF laser pumped by low cost diode lasers (2003)

We describe an extended cavity femtosecond Cr:LiSAF laser pumped by inexpensive single spatial mode diodes. Using a multi-pass cavity (MPC) to lower the repetition rate and a saturable Bragg reflector (SBR) for mode-locking, pulse energies of 0.75 nJ at a repetition rate of 8.6 MHz are achieved with durations of 39 fs and bandwidths of 20 nm in a prismless configuration. Pulse energies of 0.66 nJ at a repetition rate of 8.4 MHz with durations of 43 fs and bandwidths of 18.5 nm are generated using prisms for dispersion compensation. This laser offers performance approaching that of standard Ti:sapphire lasers at a fraction of the cost.
Training needs assessment at work: A dynamic process (1993)

Abstract In today's fast‐paced world of change, many of the performance bottlenecks found within organizations are caused by a lack of worker knowledge and skills. Because organizations lack the resources to address all their training needs, analyzing performance needs has become increasingly important. This article focuses on the dynamics of training needs analysis. Thefirst section of the article describes the role of training needs analysis within an organization. The second section describes three elements that interact to influence the needs analysis process and results. The three elements are organization characteristics, decision‐maker characteristics, and analyst characteristics. The interaction of these elements influences the process used to identify the needs, the solutions that are identified, and the final product.
Penalized Split Criteria for Interpretable Trees (2013)

This paper describes techniques for growing classification and regression trees designed to induce visually interpretable trees. This is achieved by penalizing splits that extend the subset of features used in a particular branch of the tree. After a brief motivation, we summarize existing methods and introduce new ones, providing illustrative examples throughout. Using a number of real classification and regression datasets, we find that these procedures can offer more interpretable fits than the CART methodology with very modest increases in out-of-sample loss.
Increase of electrical conductivity with pressure as an indicator of conduction through a solid phase in midcrustal rocks (1997)

Rocks freshly cored from depth at the German continental scientific drilling site (KTB) offer an opportunity to study transport properties in relatively unaltered samples resembling material in situ. Electrical conductivity σ was measured to 250 MPa pressure, and room temperature on 1 M NaCl‐saturated amphibolites from 4 to 5 km depth. An unexpected feature was an increase of σ with pressure P that appeared (anisotropically) in most samples. To characterize this behavior, we fitted the linear portion of log σ versus P to obtain two parameters: the slope dlogσ/dP (of order 10 −3 MPa −1 ) and the zero‐pressure intercept σ 0 . Samples of positive and negative slopes behave differently. Those having negative slopes show strong correlation of σ 0 with a fluid property (permeability). This behavior indicates that fluids exert the dominant control on σ 0 at low pressure when σ 0 is greatest, which is typical behavior observed in previous studies. In contrast, samples with positive slopes lack a correlation of σ 0 with permeability, indicating that fluids are less important to positive pressure behavior. Another result is that samples of negative dlogσ/dP have uncorrelated slopes and initial conductivities. In significant contrast, samples of positive slopes have the greatest P dependence for lowest initial conductivity σ 0 , that is, the less fluid, the more positive dlogσ/dP. Hence positive dlogσ/dP is consistent with reconnection of solid phases into a conductive texture better resembling that of rock at depth. Detailed examination of one sample by electron probe and scanning electron microscope reveals the presence of carbon on internal cleavage surfaces in amphibole, the most abundant mineral present. Thus carbon probably dominates the reconnection, but total σ still involves fluids as well as Fe‐Ti oxides. For the KTB location it is inferred that the reason mid to deep crustal electrical conductivities modeled from geophysical measurements are so much higher than conductivities of silicates is the presence of interconnected good conductors involving films of carbon on surfaces and other solid phases.
Multi objective optimization of line pack management of gas pipeline system (2015)

This paper addresses the Line Pack Management of the "GZ1 Hassi R'mell-Arzew" gas pipeline. For a gas pipeline system, the decision-making on the gas line pack management scenarios usually involves a delicate balance between minimization of the fuel consumption in the compression stations and maximizing gas line pack. In order to select an acceptable Line Pack Management of Gas Pipeline scenario from these two angles for "GZ1 Hassi R'mell- Arzew" gas pipeline, the idea of multi-objective decision-making has been introduced. The first step in developing this approach is the derivation of a numerical method to analyze the flow through the pipeline under transient isothermal conditions. In this paper, the solver NSGA-II of the modeFRONTIER, coupled with a matlab program was used for solving the multi-objective problem.
Cancer-predisposition gene<i>KLLN</i>maintains pericentric H3K9 trimethylation protecting genomic stability (2015)

Maintenance of proper chromatin states and genomic stability is vital for normal development and health across a range of organisms. Here, we report on the role of KLLN in maintenance of pericentric H3K9 trimethylation (H3K9me3) and genomic stability. Germline hypermethylation of KLLN, a gene uncovered well after the human genome project, has been linked to Cowden cancer-predisposition syndrome (CS) in PTEN wild-type cases. KLLN first identified as a p53-dependent tumor suppressor gene, was believed to bind randomly to DNA and cause S-phase arrest. Using chromatin immunoprecipitation-based sequencing (ChIP-seq), we demonstrated that KLLN binds to DNA regions enriched with H3K9me3. KLLN overexpression correlated with increased H3K9 methyltransferase activity and increased global H3K9me3, while knockdown of KLLN had an opposite effect. We also found KLLN to localize to pericentric regions, with loss of KLLN resulting in dysregulation of pericentric heterochromatin, with consequent chromosomal instability manifested by increased micronuclei formation and numerical chromosomal aberrations. Interestingly, we show that KLLN interacts with DBC1, with consequent abrogation of DBC1 inhibition of SUV39H1, a H3K9 methyltransferase, suggesting the mode of KLLN regulating H3K9me3. These results suggest a critical role for KLLN as a potential regulator of pericentric heterochromatin formation, genomic stability and gene expression.
A binary feedback scheme for congestion avoidance in computer networks with a connectionless network layer (1988)

We propose a scheme for congestion avoidance in networks using a connectionless protocol at the network layer. The scheme uses feedback from the network to the users of the network. The interesting challenge for the scheme is to use a minimal amount of feedback (one bit in each packet) from the network to adjust the amount of traffic allowed into the network. The servers in the network detect congestion and set a congestion indication bit on packets flowing in the forward direction. The congestion indication is communicated back to the users through the transport level acknowledgement. The scheme is distributed, adapts to the dynamic state of the networks, converges to the optimal operating point, is quite simple to implement, and has low overhead while operational. The scheme also addresses a very important aspect of fairness in the service provided to the various sources utilizing the network. The scheme attempts to maintain fairness in service provided to multiple sources. This paper presents the scheme and the analysis that went into the choice of the various decision mechanisms. We also address the performance of the scheme under transient changes in the network and for pathological conditions.
Enzymatic debriding agents are safe in wounds with high bacterial bioburdens and stimulate healing. (2008)

Collagenase and papain-urea appear beneficial and safe even in wounds with high bacterial loads, and appear to significantly aid extent and rate of healing, probably by lowering bacterial burden through their positive enzymatic actions on bacteria and necrotic tissue.
Diagnosis of Myocardial Ischemia During Ventricular Pacing (2000)

Discordant ST elevation > 5 mm was recently described as an electrocardiographic sign with good specificity and moderate sensitivity for the diagnosis of acute myocardial infarction during right ventricular pacing. This report shows that the same sign may occur transiently during myocardial ischemia and also serve as a diagnostic marker.
Initial Events in Establishing Vaginal Entry and Infection by Human Immunodeficiency Virus Type-1 (2007)

Understanding the initial events in the establishment of vaginal human immunodeficiency virus type-1 (HIV-1) entry and infection has been hampered by the lack of appropriate experimental models. Here, we show in an ex vivo human organ culture system that upon contact in situ, HIV-1 rapidly penetrated both intraepithelial vaginal Langerhans and CD4(+) T cells. HIV-1 entered CD4(+) T cells almost exclusively by CD4 and CCR5 receptor-mediated direct fusion, without requiring passage from Langerhans cells, and overt productive infection ensued. By contrast, HIV-1 entered CD1a(+) Langerhans cells primarily by endocytosis, by means of multiple receptors, and virions persisted intact within the cytoplasm for several days. Our findings shed light on the very earliest steps of mucosal HIV infection in vivo and may guide the design of effective strategies to block local transmission and prevent HIV-1 spread.
Classement des adverbes : Pas la Couleur, rien que la nuance ? (1990)

Blumenthal Peter. Classement des adverbes : Pas la Couleur, rien que la nuance ?. In: Langue française, n°88, 1990. Classification des adverbes, sous la direction de Henning Nølke. pp. 41-50.
Service-oriented Architectures in Industrial Automation (2006)

The advent of the service-oriented architecture (SOA) paradigm is a major trend in the ICT industry at large. Based on open standards and protocols and enjoying broad-based industry adoption, it is set to revolutionize the computing and communications landscape in the years to come. Current literature abounds with articles on SOA - especially SOA implemented using Web services. However, SOA is much more than a buzz word. Being an enterprise-wide architectural style that promotes vendor neutrality, interoperability, and loose-coupling between service providers and consumers, it is rapidly becoming the de-facto foundation for enterprise architectures. Ever-increasing miniaturization allows driving intelligence down to the device level, thus favoring the adoption of the SOA paradigm in the embedded-device space, down to sensors and actuators. This will enable radically new device networking architectures and pave the way for application of a uniform communication paradigm down from the shop floor up to the top floor, thus breaking down current technological barriers. In turn, these evolutions hold the promise of greatly increasing the agility of future industrial enterprises. This tutorial exposes the foundations of the SOA paradigm in general and of its use in the device space in particular, explains how SOA for devices can be implemented using the Devices Profile for Web Services, and outlines the benefits it brings in the industrial sector, as illustrated by the ground breaking experience of the SIRENA (http://www.sirena-itea.org) project. It further plots some future directions and discusses the potential benefits of using advanced concepts like semantic Web services for automating service selection, invocation and composition, so as to facilitate rapid reconfiguration.
Minimizing Water Invasion into Kazhdumi Shale Using Nanoparticles (2015)

Fluid invasion from water-based drilling mud (WBDM) into the shale formations causes swelling, high pressure zone near the wellbore wall, and eventually wellbore instability problems during drilling operations. For the stability of the wellbore, physical plugging of nanoscale pore throats could be considered as a logical approach toward avoiding the fluid invasion into the shale formation. This paper reports the effect of silica nanoparticles (NPs) as a physical sealing agent on the water invasion into Kazhdumi shale. To this end, pressure penetration apparatus was implemented. Typical WBDM in contact with Kazhdumi shale at different concentrations of NPs with different sizes was studied. The results indicated that the addition of NPs to the WBDM decreased water invasion into Kazhdumi shale. WBDM having 10 wt.% of 25 nm NPs reduced fluid invasion up to 72.76%.
Interactive Highway Safety Design Model: accident predictive module (1994)

The Interactive Highway Safety Design Model (IHSDM) being developed by the Federal Highway Administration will provide highway design engineers with safety information on the relationships between geometrics and accidents in a usable format and will guide the designer in evaluating the safety of alternative alignments. This article discusses the accident predictive module of IHSDM. The IHSDM architecture connects the accident predictive module to the data stored in the computer-aided design (CAD) package. Eventually, IHSDM will allow the other modules, especially the driver module and the traffic module, to communicate with the accident predictive module. The development of the accident predictive module will be an evolutionary process in three phases. Phase 1 is the short-term goal and deals only with two-lane, rural roads. Phase 2 will address both roadway and roadside accidents and will continue to develop the interface between the accident predictive module and the CAD package. Three submodels will be developed: roadways, intersections, and interchange ramps. Phase 3 is a long-term goal that will establish the relationship between geometric design elements, accidents, and driver performance. A sidebar provides details on the status of the accident predictive module's intersection submodel.
Mechanisms in the Cycle of Violence (1990)

Two questions concerning the effect of physical abuse in early childhood on the child's development of aggressive behavior are the focus of this article. The first is whether abuse per se has deleterious effects. In earlier studies, in which samples were nonrepresentative and family ecological factors (such as poverty, marital violence, and family instability) and child biological variables (such as early health problems and temperament) were ignored, findings have been ambiguous. Results from a prospective study of a representative sample of 309 children indicated that physical abuse is indeed a risk factor for later aggressive behavior even when the other ecological and biological factors are known. The second question concerns the processes by which antisocial development occurs in abused children. Abused children tended to acquire deviant patterns of processing social information, and these may mediate the development of aggressive behavior.