gebhart/patrepeval huggingface dataset:
Rapid Hydrolysis of RNA with a Cu<sup>II</sup> Complex (1995)

The methyl groups in copper complex 1 not only prevent dimerization but also activate the complex for RNA hydrolysis. The half-life for the hydrolysis of ApA (0.5 mM) promoted by 1 is only 3 min. Thus 1 is currently the most effective transition metal complex for hydrolyzing RNA.
ChemInform Abstract: Formation of C60Ph12 by Electrophilic Aromatic Substitution. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A comparison of midazolam nasal spray and diazepam rectal solution for the residential treatment of seizure exacerbations (2009)

Rectal diazepam is established as a standard rescue or emergency treatment for seizure or status epilepticus; however, the rectal route of administration has not been universally accepted. To determine if an alternative route of administration of a benzodiazepine was equally effective, we compared a novel midazolam HCl concentrated nasal spray (MDZ-n) with diazepam rectal solution (DZP-r) in the treatment of prolonged seizures in a residential epilepsy center. In 21 adult patients with medically refractory epilepsy, 124 seizure-exacerbations were treated by their caregivers, alternatively with 10 mg DZP-r and 10 mg concentrated MDZ-n, two or three treatments with each medication for each patient. No difference was demonstrated in efficacy or time to effect between the two drugs. Common treatment emerging adverse effects were drowsiness for both drugs in more than 50% of the administrations, and short-lasting local irritation after 29% of MDZ-n. No severe adverse events occurred. The nasal spray was preferred to the rectal solution by 16 of 21 caregivers and patients conjointly. MDZ-n was equal to DZP-r with respect to efficacy and side effects in the suppression of seizure exacerbations. The majority of patients and caregivers preferred the nasal spray over the rectal formulation.
New saturable-core Fault Current Limiter topology with reduced core size (2009)

Installation of new generating units and increased penetration of distributed generators (DGs) in the power systems increase the total power transmitted in the power grid. In the case of a fault, the amount of power captured by a short circuit is enlarged, leading to higher peaks of the fault currents and, consequentially, to higher stresses to the power system components. Installations of fault current limiters (FCLs) are expected to prevent expensive upgrade and replacement of the components exposed to the over-stresses. Inductive FCL are particularly interesting due to their inherent reaction to a fault. However, some challenges are to be solved: excessive weight and induced over-voltage across the DC winding. The goal of this paper is to introduce a new configuration of the inductive FCL, where the amount of the required material has been reduced considerably and the induced over-voltage across the DC winding is decreased. Employment of one core per-phase instead of two reduces the amount of magnetic material. The core has three legs, where the middle leg is used as a shunt path for the AC flux. It enables a gap insertion in the AC magnetic circuit without influencing the DC magnetic circuit, i.e. amount of DC winding material. This means that a smaller core (less magnetic material) can be used for a same power level. The simulation results obtained from FCL models created in SaberDesigner are presented. They have been confirmed through the testing of the lab-scale prototype.
TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton+ (2004)

Subversion of host cell actin microfilaments is the hallmark of enterohaemorrhagic (EHEC) and enteropathogenic (EPEC) Escherichia coli infections. Both pathogens translocate the trans-membrane receptor protein-translocated intimin receptor (Tir), which links the extracellular bacterium to the cell cytoskeleton. While both converge on neural Wiskott-Aldrich syndrome protein (N-WASP), Tir-mediated actin accretion by EPEC and EHEC differ in that Tir(EPEC) requires both tyrosine phosphorylation and the host adaptor protein Nck, whereas Tir(EHEC) is not phosphorylated and utilizes an unidentified linker. Here we report the identification of Tir-cytoskeleton coupling protein (TccP), a novel EHEC effector that displays an Nck-like coupling activity following translocation into host cells. A tccP mutant did not affect Tir translocation and focusing but failed to recruit alpha-actinin, Arp3, N-WASP and actin to the site of bacterial adhesion. When expressed in EPEC, bacterial-derived TccP restored actin polymerization activity following infection of an Nck-deficient cell line. TccP has a similar biological activity on infected human intestinal explants ex vivo. Purified TccP activates N-WASP stimulating, in the presence of Arp2/3, actin polymerization in vitro. These results show that EHEC translocates both its own receptor (Tir) and an Nck-like protein (TccP) to facilitate actin polymerization.
A Micro Air Vehicle Navigation System (2006)

A description of the design, operation, and test results of a Micro-Electro-Mechanical (MEMS) based navigation system for the Micro Air Vehicle (MAV) is presented. The MAV is a small Unmanned Aerial Vehicle (UAV) built by Honeywell. It is one of the first applications to use Honeywell's new HG1930 MEMS inertial measurement unit (IMU). The raw IMU measurements are transmitted via a serial interface to a processor board where the inertial solution is blended in a Kalman filter with measurements from GPS, a barometric altimeter, and a magnetometer. The navigation is performed by Honeywell's ECTOS IIc navigation software. The modular ECTOS architecture allows easy customization for use with various IMUs and aiding sources, creating a flexible naviga- tion solution which can be customized to the user's requirements. The MAV has been extensively flight tested both on and off tether. Results are presented showing the performance of the MAV navigation system. I. MICRO AIR VEHICLE OVERVIEW The Micro Air Vehicle (MAV) is a small unmanned aerial vehicle (UAV) built by Honeywell. The MAV's unique design represents a new generation of lightweight, low cost UAVs. The MAV and accompanying ground station can be transported in a backpack by a single soldier, providing unprecedented situational awareness to front line commanders, and short circuiting the traditional long intelligence chain to the field. The airframe is a ducted fan design, allowing the MAV to hover and stare for extended periods of time. Made of lightweight composite materials, the airframe encloses a bladder style fuel tank which provides consistent fuel flow to a small engine regardless of vehicle orientation. The MAV is fitted with forward and down looking cameras, which are located in a payload pod. Exchangeable pods, containing different types of sensors, can be easily mounted in the field without tools. The Micro Air Vehicle environment represents some chal- lenging navigation problems. The navigation system is greatly constrained in size, weight and cost. It must operate in an environment characterized by high vibration and exposure to the elements and extreme temperatures. It must remain functional with temporary degradation or loss of GPS signals, as well as magnetic interference affecting the compass. The navigation system must be simple and reliable enough to be operated by soldiers with minimal training, and be capable of self diagnostics. In addition, the ducted fan design of the airframe presents some unique flight characteristics which the navigation system must tolerate. These include long periods of hovering, high yaw rates, and large forward pitches during flight which can change the visible GPS constellation.
Sensitization of Photohemolysis by a New Extraction from Flowers and Aerial Parts of Cichorium Pumilum Jacq: Effects of Inulin and Hydrogen Peroxide (2007)

Addition of inulin and hydrogen peroxide to new photosensitizers extracted from the flowers and aerial parts of the chicory (Cichorium Pumilum Jacq) have been investigated. Some of the isolated photosensitizers remain unidentified compounds. Chicory extracts are found to be dependent on light and temperature. Higher photohemolysis rate was noticed under the influence of light as compared to temperature. The effect of H2O2 on phototoxicity reported in this study showed a rapid reduction in the fractional hemolysis percentage at higher temperature. Compared to erythrocytes with higher concentrations and under the influence of solar irradiance 505.29Â±24.96w/m2, erythrocytes with lower concentrations of inulin and H2O2 were ruptured faster. Samples with 0.95 mg/ml of herb extract and different concentrations of inulin (1mg/ml â 2mg/ml) shows no temperature effects at 40Â°C in the absent of sunlight.
Ein Gedenkstein in Vik auf Island : "Zum Gedenken an die Seeleute, die in der deutschen Islandfischerei ihr Leben verloren" (2002)

Johann Heinrich von Thünen-Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries began publishing the Informationen aus der Fischereiforschung = Information on Fishery Research in 2010.
Overview on DMD Exon Skipping (2012)

Antisense-mediated exon skipping to restore the disrupted dystrophin reading frame is currently in clinical trials for Duchenne muscular dystrophy. This chapter describes the rationale of this approach and gives an overview of in vitro and in vivo experiments with antisense oligonucleotides and antisense genes. Finally, an overview of clinical trials is given and outstanding questions and hurdles are discussed.
Performance of pavements constructed from continuously reinforced concrete overlaid with asphalt surfacing (2008)

In the Design Manual for Roads and Bridges, the preferred rigid pavement construction is continuously reinforced concrete (CRC), either in the form of continuously reinforced concrete pavement (CRCP) or continuously reinforced concrete base (CRCB). CRC contains no intermediate transverse expansion or contraction joints. Cracks designed to occur under thermal changes occur in the transverse direction and hardly affect the integrity of the pavement because of steel reinforcement and an aggregate interlock. Asphalt surfacing improves the durability of the pavement. The performance of CRC was assessed by looking at a number of sites in the UK. Performance, temperature variations, reflection cracking, bond strength and durability were examined. The tests and results are described and evaluated in detail with supporting tables and illustrations.
Radio frequency nanowire resonators and <i>in situ</i> frequency tuning (2009)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Wayne Y. Fung, Eric N. Dattoli, Wei Lu; Radio frequency nanowire resonators and in situ frequency tuning. Appl. Phys. Lett. 18 May 2009; 94 (20): 203104. https://doi.org/10.1063/1.3139750 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioApplied Physics Letters Search Advanced Search |Citation Search
HRQOL implications of treatment with dexamethasone for children with acute lymphoblastic leukemia (ALL) (2005)

Dexamethasone is increasingly used in the treatment of ALL and has been linked with improved survival rates. Long-term use of dexamethasone raises questions about neuropsychologic toxicity. Although HRQOL increased significantly over the year for all children, the extent of this increase did not differ by chemotherapy. These results should contribute to lessened concerns about use of dexamethasone in the treatment of ALL.
Real-time software MPEG-1 video decoder design for low-cost, low-power applications (2002)

This paper presents a real-time MPEC-1 video decoder implemented in software on a DSP-enhanced, 160-mW, 100-MHz, 32-bit microprocessor. The processor's DSP-oriented instructions improves the performance of generic DSP operations such as the inverse discrete cosine transform, while fast software algorithms that perform parallel operation on packed-pixel data are developed for processes unique to video decoding such as motion compensation. Furthermore, to reduce the clock count as well as the instruction count, load/store scheduling and cache miss reduction are performed. In total, the processor can achieve 30 frames/sec MPEC-1 video decoding at a cost and power dissipation (160 mW) comparable to dedicated LSIs.
Adaptive stabilization of high-order nonholonomic systems with unknown control coefficients (2011)

This paper solves the problem of globally stabilizing adaptive control design for a class of high-order nonholonomic systems, by skillfully using the discontinuous transformation of coordinates and the method of adding a power integrator. Compared with the existing literature, the control coefficients of the systems are unknown and no known constants can (lower and upper) bound them, and in the designed adaptive controller, only one updating law is needed to dynamically compensate the unknowns in the system control coefficients. A numerical simulation is provided to demonstrate the validness of the proposed method.
[Increase in yeast and bacterial sensitivity to inhibitors and riboflavin as affected by high sulfate and phosphate concentrations]. (1981)

Cultivation of the yeast Pichia guilliermondii in a medium with a high content of sulfate or phosphate ions (0.6 M and higher) increased its susceptibility to actinomycin D and 7-methyl-8-trifluoromethyl 10-(1'-D-ribityl)isoalloxazin, and analog of riboflavin, and decreased the requirement of the riboflavin-dependent mutant P7 in exogenous vitamin B2. The protoplasts of the yeast were also very susceptible to actinomycin D when they were incubated in a medium with a high sulfate concentration. Sulfate and phosphate ions elevated the susceptibility to actinomycin D in the following yeasts, apart from P. guilliermondii: Pichia pinus, Saccharomyces cerevisiae, Torulopsis candida, hansenula polymorpha, Schwanniomyces occidentalis, Candida utilis and Candida tropicalis. The growth of Escherichia coli was also very susceptible to actinomycin D when the bacterium was cultivated in medium with an elevated phosphate concentration (0.2 M). High phosphate or sulfate concentrations can be used in experiments aimed at studying the effect of transcription inhibitors (actinomycin D, 8-hydroxyquinoline) on the induction of alpha-glucosidase in P. guilliermondii.
SPRAY DRYING CHARACTERISTICS BY A CENTRIFUGAL PRESSURE NOZZLE WITH LARGE ORIFICE DIAMETER (1986)

Abstract A study was made of a centrifugal pressure nozzle with large orifice diameter (8-10 nun) for producing dry milk in capacity of 2-3 tons per hour to develop some performance data on spray distribution, drop size distribution, and capacity with changing spray drying conditions such as nozzle pressure, orifice diameter and spray angle. Experimental results were shown as follows. (1) A centrifugal pressure nozzle of large capacity such as 5,000- 5,500 l/hr at 150 kg/cm2 spray pressure and 110°s ray angle was designed by using the nozzle parameter Si/dedi√di/di. (2) Atomization characteristics were greatly affected by the ratio of orifice diameter (de) to the length (L) of the nozzle core. The smaller the ratio, around 0.125, the better are the atomizing effects. (3) The large orifice can be used at least 3,000 hr in the spray drying operation for milk without any wear in the orifice although it is only made of stainless steel. As a result, a spray dryer of large capacity for dry milk has been operated by a mono nozzle with a large orifice without any trouble for a long time
Automatic worst case pattern generation using neural networks & genetic algorithm for estimation of switching noise on power supply lines in CMOS circuits (2004)

In our approach, we use ATE (automatic test equipment) to teach a neural network (NN) to correctly classify a set of worst case input patterns with respect to the maximum instantaneous current. This can be thought of as learning a behavior of chip power consumption change due to different input patterns applied. We then further optimize this set of (NN) worst case patterns using a genetic algorithm (GA). The final set of worst case patterns can efficiently identify a defective or weakness due to power supply noise as well as locate the defect or weakness within the design. To the best of our knowledge, this is the first NN learning and GA self-optimization ATE-based approach for practical application in silicon analysis automation. Our practical experimental results demonstrate the enlarged fault coverage obtained with this approach.
Rashba spin splitting in inversion layers on<b><i>p</i></b>-type bulk InAs (2000)

The dependence of the spin-orbit interaction on electron density in inversion layers of metal-oxide-semiconductor field-effect transistors on p-type InAs is studied by magnetotransport at liquid-helium temperatures. We observe beating patterns in the Shubnikov--de Haas oscillations, which manifest the Rashba effect in a triangular surface potential. Taking subband nonparabolicity into account we evaluate Rashba parameters $\ensuremath{\alpha}$ that increase with electron density ${n}_{s}$ reaching a value $\ensuremath{\alpha}=3\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}11}\mathrm{eV}\mathrm{}\mathrm{m}$ at densities ${n}_{s}>~2.2\ifmmode\times\else\texttimes\fi{}{10}^{12}{\mathrm{cm}}^{\ensuremath{-}2}.$ Implications for the spin-dependent transport in spin-polarized high-electron-mobility transistors utilizing InAs quantum wells are discussed.
Cancer stem-like sphere cells induced from de-differentiated hepatocellular carcinoma-derived cell lines possess the resistance to anti-cancer drugs (2014)

Our novel method successfully induced cancer stem-like cells, which possessed chemoresistance that was related to the cell cycle, drug efflux, and ROS.
Morphology discrimination criterion wavelet improves rhythm discrimination in single-chamber implantable cardioverter-defibrillators: Spanish Register of morphology discrimination criterion wavelet (REMEDIO) (2009)

Wavelet discrimination criteria in single-chamber ICDs as the sole discriminator can significantly reduce inappropriate therapy for SVT, not only in the range of VTs in the slowest analysed range (340-500 ms for this study) but also for faster VTs. No significant clinical consequences were found when the algorithm was used, but final data should prompt the use of the algorithm in combination with a high rate time-out feature.
Enlarged median nerve in idiopathic carpal tunnel syndrome (2000)

To delineate change in median nerve size in carpal tunnel syndrome (CTS), we compared ultrasonograms of nerve cross-sections from patients (201 wrists of 125 women with idiopathic CTS) and controls (200 dominant wrists of 200 women). Major and minor axes, cross-sectional area, and the flattening ratio (major axis/minor axis) were measured at four levels: 1, distal edge of the flexor retinaculum; 2, center of the hook of the hamate; 3, wrist crease; and 4, distal one-third level of the forearm. Axes and areas were greater in the patients at levels 1, 2, and 3. The flattening ratio was greater in the controls at levels 1 and 2, and in the patients at level 3. When the groups were combined, there were linear correlations between the cross-sectional nerve area and electrophysiologic severity at levels 1, 2, and 3. These findings indicate that idiopathic CTS is characterized by severity-correlated intracarpal enlargement of the median nerve and not by compressive deformation, such as a reduction in the caliber of the nerve.
Oxidative Stress in Rats With Heatstroke-Induced Cerebral Ischemia (2002)

Taken together, these results indicate that hydroxyl radicals mediate cerebral ischemic injury associated with heatstroke.
Measurement of Immunoglobulin Synthesis Using the ELISPOT Assay (1996)

The enzyme-linked immunospot (ELISPOT) assay for detection of single antibody-secreting cells has become the best alternative method to the conventional plaque-forming cell (PFC) assays. Among its several advantages are better antigen stability and specificity as well as fewer limitations in the diversity of antigens that can be used in the assay. In addition, the ELISPOT assay can be used to detect two antigenically different secreted antibodies simultaneously by two-color analysis and offers the unique possibility of quantifying the number of antibody molecules secreted per cell. Finally, the assay can be used to detect single antibody-secreting cells in tissues that usually confront the immunologist with difficulties, e.g., gut lamina propria from humans or mice. This unit presents the ELISPOT assay in three steps: coating of antigen to a solid phase, incubation of antibody-producing cells in appropriate dilution, and detection of the antigen-antibody complex formed at the site of the active antibody-secreting cell. The assay can be performed using polystyrene plates or nitrocellulose membrane in microtiter plates or using nitrocellulose membrane in a blotting manifold.
Multisensory design: Reaching out to touch the consumer (2011)

Abstract Touch plays an important, if often underacknowledged, role in our evaluation/appreciation of many different products. It is unsurprising, therefore, that there has been such a recent growth of interest in “tactile branding” and tactile marketing. This article reviews the evidence from the fields of marketing, psychology, and cognitive neuroscience, demonstrating just how important the feel of a product, not to mention the feel of its packaging, can be in determining people's overall product evaluation. Problems for tactile design associated with the growth of the aging population, and the growth of Internet‐based shopping, are highlighted. The critical role that touch can play in multisensory product design, appreciation, and marketing is also discussed, as is the increasingly frequent use by marketers of synesthetic correspondences to evoke tactile sensations via the visual and auditory modalities. We put forward the argument that tactile stimulation may influence multisensory product evaluation by means of affective ventriloquism : Our suggestion is that the hedonic attributes of a product perceived via one modality (such as touch) can “pull” (or bias) a person's estimates of the quality and pleasantness of the product derived from other sensory modalities into alignment, and by so doing, modulate a person's overall (multisensory) product experience. What is more, powerful mathematical modeling approaches now exist to predict the magnitude of this kind of intersensory (or crossmodal) interaction effect, hence offering the promise of a more scientific approach to tactile design/marketing in the coming years. © 2011 Wiley Periodicals, Inc.