gebhart/patrepeval huggingface dataset:
Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein. (1987)

Plasma cholesteryl esters, synthesized in the high density lipoproteins (HDL), may be transferred to other lipoproteins by a cholesteryl ester transfer protein (CETP). We found a twofold increase in mass transfer of cholesteryl ester from HDL to apoB-containing lipoproteins in incubated hypercholesterolemic rabbit plasma compared with control. There was a two- to fourfold increase in the activity of CETP, measured in an isotopic assay in hypercholesterolemic plasma. A CETP-like molecule was isolated in increased amounts from hypercholesterolemic plasma. Incubated plasma from four dysbetalipoproteinemic subjects also showed an increase (threefold) in cholesteryl ester mass transfer, compared with normolipidemic controls. There was a twofold increase in the activity of CETP, assayed in whole or lipoprotein-free plasma. Thus, there is increased transfer of cholesteryl esters from HDL to potentially atherogenic apoB-containing lipoproteins in dyslipidemic rabbit and human plasma. The enhanced transfer results in part from increased activity of CETP, possibly reflecting an increase in CETP mass.
1,25(<scp>OH</scp>)<sub>2</sub>‐vitamin <scp>D</scp><sub>3</sub> enhances the stimulating effect of leucine and insulin on protein synthesis rate through <scp>A</scp>kt/<scp>PKB</scp> and m<scp>TOR</scp> mediated pathways in murine <scp>C</scp>2<scp>C</scp>12 skeletal myotubes (2013)

1,25(OH)2D3 sensitizes the Akt/mTOR-dependant pathway to the stimulating effect of leucine and insulin, resulting in a further activation of protein synthesis in murine C2C12 skeletal myotubes.
Digital dealing: how e-markets are transforming the economy (2002)

Discusses auction deal engines at both the consumer and the business-to-business level, stock and bond auctions, procurement auctions, real-time deal engines, posted-price deal engines, antitrust issues, and the future of e-markets.
On the Thermal Dissociation of Organic Compounds. XI. The Effects of the Substituents on the Thermal Dissociation of Urethans in Amine Solvent (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOn the Thermal Dissociation of Organic Compounds. XI. The Effects of the Substituents on the Thermal Dissociation of Urethans in Amine SolventTeruaki Mukaiyama and Masaru IwanamiCite this: J. Am. Chem. Soc. 1957, 79, 1, 73–76Publication Date (Print):January 1, 1957Publication History Published online1 May 2002Published inissue 1 January 1957https://pubs.acs.org/doi/10.1021/ja01558a019https://doi.org/10.1021/ja01558a019research-articleACS PublicationsRequest reuse permissionsArticle Views211Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cell Surface Heparan Sulfate Is a Receptor for Human Herpesvirus 8 and Interacts with Envelope Glycoprotein K8.1 (2001)

An immunodominant envelope glycoprotein is encoded by the human herpesvirus 8 (HHV-8) (also termed Kaposi's sarcoma-associated herpesvirus) K8.1 gene. The functional role of glycoprotein K8.1 is unknown, and recognizable sequence homology to K8.1 is not detectable in the genomes of most other closely related gammaherpesviruses, such as herpesvirus saimiri or Epstein-Barr virus. In search for a possible function for K8.1, we expressed the ectodomain of K8.1 fused to the Fc part of human immunoglobulin G1 (K8.1DeltaTMFc). K8.1DeltaTMFc specifically bound to the surface of cells expressing glycosaminoglycans but not to mutant cell lines negative for the expression of heparan sulfate proteoglycans. Binding of K8.1DeltaTMFc to mammalian cells could be blocked by heparin. Interestingly, the infection of primary human endothelial cells by HHV-8 could also be blocked by similar concentrations of heparin. The specificity and affinity of these interactions were then determined by surface plasmon resonance measurements using immobilized heparin and soluble K8.1. This revealed that K8.1 binds to heparin with an affinity comparable to that of glycoproteins B and C of herpes simplex virus, which are known to be involved in target cell recognition by binding to cell surface proteoglycans, especially heparan sulfate. We conclude that cell surface glycosaminoglycans play a crucial role in HHV-8 target cell recognition and that HHV-8 envelope protein K8.1 is at least one of the proteins involved.
Effect of pH on the microstructure and texture of whey protein concentrates and isolate gels (1996)

The objective of this study was to determine the effect of pH on the fundamental rheological properties of whey protein concentrates (WPC) and isolate (WPI) gels and on the microstructure of WPI gels. Higher pH caused a significant increase in shear strain and shear stress values of WPCs and WPI gels. At some pH value a drop in strain and stress was observed. For whey protein preparations with higher protein content this drop occurred at lower pH values. Particulate microstructures of WPI gels were produced in the pH range 4-7. Fine-stranded gel was produced at pH 3 while mixed and fine-stranded gels were produced at pH value above 7. There was no relationship between microstructure and the shear strain values. The highest shear stress value of WPI gels was observed at pH 8. At this pH a mixed microstructure was produced.
Adding Memory Processing Behaviors to the Fuzzy Behaviorist Approach (Fba): Resolving Limit Cycle Problems in Autonomous Mobile Robot Navigation (1999)

ABSTRACTMost fuzzy logic-based reasoning schemes developed for robot control are fully reflexive, i.e., the reasoning modules consist of fuzzy rule bases that represent direct mappings from the stimuli provided by the perception systems to the responses implemented by the motion controllers. Due to their totally reflexive nature, such reasoning systems can encounter problems such as infinite loops and limit cycles. In this paper, we propose an approach to remedy these problems by adding a memory and memory-related behaviors to basic reflexive systems. Three major types of memory behaviors are addressed: memory feeding, memory management, and memory utilization. The concepts underlying these major classes of behaviors are first presented. An example of their implementation is then described for the recognition of limit cycles during the sensor-based navigation of mobile robots. Results of sample cases involving an autonomous robot navigating in a priori unknown environments are presented and discussed to i...
<i>Homo-Freidinger</i> Lactams: Stereoselective Synthesis of 4-Aminopiperidin-2-one Derivatives from Aspartic Acid (1998)

Starting from aspartic acid a stereoselective synthesis of enantiomerically pure 4-aminopiperidin-2-ones which can serve as conformationally restrained β-amino acid equivalents in peptidomimetics is described. The synthesis is based on the regioselective functionalization of the 1,4-bis-electrophile 2b and a diastereoselective introduction of various side chain equivalents into the lactam-α-position of 4b, c.
Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis (2000)

PCAF plays a role in transcriptional activation, cell-cycle arrest, and cell differentiation in cultured cells. PCAF contributes to transcriptional activation by acetylating chromatin and transcription factors through its intrinsic histone acetylase activity. In this report, we present evidence for the in vivo function of PCAF and the closely related PCAF-B/GCN5. Mice lacking PCAF are developmentally normal without a distinct phenotype. In PCAF null-zygous mice, protein levels of PCAF-B/GCN5 are drastically elevated in lung and liver, where PCAF is abundantly expressed in wild-type mice, suggesting that PCAF-B/GCN5 functionally compensates for PCAF. In contrast, animals lacking PCAF-B/GCN5 die between days 9.5 and 11.5 of gestation. Normally, PCAF-B/GCN5 mRNA is expressed at high levels already by day 8, whereas PCAF mRNA is first detected on day 12.5, which may explain, in part, the distinct knockout phenotypes. These results provide evidence that PCAF and PCAF-B/GCN5 play distinct but functionally overlapping roles in embryogenesis.
Dehydrierungsreaktionen mit Gallussäureestern (1984)

Abstract Gallussäure‐methylester ( 1 ) liefert mit Meerrettich‐Peroxidase den 3,3′,4,4′,5,5′‐Hexahydroxy‐2,2′‐diphensäure‐dimethylester ( 2 ), der leicht in Ellagsäure ( 4 ) übergeht, sowie Purpurogallin‐4‐carbonsäure‐methylester ( 3 ). Die analoge Reaktion mit den Digalloylestern von Ethandiol, 1,3‐Propandiol, 1,4‐Butandiol, trans ‐1,2‐Cyclohexandiol, 3,6‐Digalloylglucose und Pentagalloylglucose führt nicht zu den Diphensäurederivaten, sondern nur zu 4 . Luftoxidation von 1 in alkalischem Milieu führt teils zu 4 , zum anderen Teil zum 1‐Benzofuranderivat 9 , dessen bemerkenswerte Reaktionen beschrieben werden. Unter Einwirkung von Alkali wird zunächst der Furanring geöffnet, und von hier aus gelangt man zum Acconitsäurederivat 11 , zum Naphthalinsystem 12 oder zur Benzoxepinverbindung 14 . Mit Eisen(III)‐chlorid als Oxidationsmittel wird aus 1 Ellagsäure ( 4 ) und das Furanderivat 15 erhalten.
Microwave wideband tunable oscillators using coherent arrays of Josephson junctions (1981)

Coherent microwave radiation from arrays containing up to 100 indium microbridges has been directly detected. As expected the power scales as N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and the linewidth as 1/N for an array containing N junctions. Design criteria and fabrication methods for these arrays are discussed.
Effects of fractures on NMO velocities and <i>P</i> -wave azimuthal AVO response (2002)

Abstract This paper attempts to explain the relationships between fractured medium properties and seismic signatures and distortions induced by geology-related influences on azimuthal AVO responses. In the presence of vertically aligned fractures, the relationships between fracture parameters (fracture density, fracture aspect ratio, and saturated fluid content) and their seismic signatures are linked with rock physics models of fractured media. The P-wave seismic signatures studied in this paper include anisotropic parameters (δ(v), ε(v), and γ(v)), NMO velocities, and azimuthal AVO responses, where δ(v) is responsible for near-vertical P-wave velocity variations, ε(v) defines P-wave anisotropy, and γ(v) governs the degree of shearwave splitting. The results show that in gas-saturated fractures, anisotropic parameters δ(v) and ε(v) vary with fracture density alone. However, in water-saturated fractures δ(v) and ε(v) depend on fracture density and crack aspect ratio and are also related to Vp/VS and Vp of background rocks, respectively. Differing from δ(v) and ε(v), γ(v) is the parameter most related to crack density. It is insensitive to the saturated fluid content and crack aspect ratio. The P-wave NMO velocities in horizontally layered media are a function of δ(v), and their properties are comparable with those of δ(v). Results from 3-D finite-difference modeling show that P-wave azimuthal AVO variations do not necessarily correlate with the magnitude of fracture density. Our studies reveal that, in addition to Poisson's ratio, other elastic properties of background rocks have an effect on P-wave azimuthal AVO variations. Varying the saturated fluid content of fractures can lead to azimuthal AVO variations and may greatly change azimuthal AVO responses. For a thin fractured reservoir, a tuning effect related to seismic wavelength and reservoir thickness can result in variations in AVO gradients and in azimuthal AVO variations. Results from instantaneous frequency and instantaneous bandwidth indicate that tuning can also lead to azimuthal variations in the rates of changes of the phase and amplitude of seismic waves. For very thin fractured reservoirs, the effect of tuning could become dominant. Our numerical results show that AVO gradients may be significantly distorted in the presence of overburden anisotropy, which suggests that the inversion of fracture parameters based on an individual AVO response would be biased unless this influence were corrected. Though P-wave azimuthal AVO variations could be useful for fracture detection, the combination of other types of data is more beneficial than using P-wave amplitude signatures alone, especially for the quantitative characterization of a fractured reservoir.
A 640 mW high accuracy 8-bit 1 GHz flash ADC encoder (2003)

This paper presents a high accuracy low-power encoder for a high-speed Analog-to-Digital Converter (ADC). High speed operation is obtained by using Gallium Arsenide technology, while low-power dissipation is reached by using the PCFL logic family. As essential part of an 8-bit 1 GHz flash ADC encoder, a PCFL 4-bit encoder has been designed and fabricated. Measurement results are reported verifying the expected low power dissipation.
On the definition of total harmonic distortion and its effect on measurement interpretation (2005)

The existence of two different definitions for total harmonic distortion (one in comparison to the fundamental and one in comparison to the signal's root mean square) might cause ambiguity and misinterpretation of measured data. The difference between those definitions is stressed out in this letter. It is suggested that total harmonic distortion measurements in the context of power systems should always adopt the first definition and never the second.
High efficiency single photon detection via frequency up-conversion (2004)

Abstract We propose a method of single photon detection of infrared (IR) photons at potentially higher efficiencies and lower noise than allowed by traditional IR band avalanche photodiodes (APDs). By up-converting the photon from the IR, e.g. 1550 nm, to a visible wavelength in a nonlinear crystal, we can utilize the much higher efficiency of silicon APDs at these wavelengths. We have used a periodically poled lithium niobate (PPLN) crystal and a pulsed 1064 nm Nd:YAG laser to perform the up-conversion to a 631 nm photon. We observed conversion efficiencies as high as ∼ 80%, and demonstrated scaling down to the single photon level while maintaining a background of 3 ×s; 10−4 dark counts per count. We also propose a 2-crystal extension of this scheme, whereby orthogonal polarizations may be up-converted coherently, thus enabling complete quantum state transduction of arbitrary states.
The Putative Role of Homoconjugation in Radical Cations: Electron Transfer Photochemistry of 7-Methylenenorbornadiene and 7-Methylenequadricyclane (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Putative Role of Homoconjugation in Radical Cations: Electron Transfer Photochemistry of 7-Methylenenorbornadiene and 7-MethylenequadricyclaneHengxin Weng, Xue-Mei Du, and Heinz D. RothCite this: J. Am. Chem. Soc. 1995, 117, 1, 135–140Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://pubs.acs.org/doi/10.1021/ja00106a017https://doi.org/10.1021/ja00106a017research-articleACS PublicationsRequest reuse permissionsArticle Views96Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
An insertable P-31 RF coil for dual-frequency magnetic resonance imaging & spectroscopy (2008)

Application of nuclear magnetic resonance spectroscopy in metabolic studies usually includes simultaneous excitation at two different frequencies. RF coupling between the two coils has been a problem in the past, resulting in reduced field strength from the (1)H coil. A modular surface coil was designed and constructed for (1)H and (31)P at 4.7 Tesla; RF traps were designed and optimized to minimize the field-degrading coupling current, and trap performance was analyzed in terms of improvement in signal-to-noise-ratio and field sensitivity pattern of the proton coil. The modular design in conjunction with the optimized traps permits the possibility of insertion of the phosphorus coil as an 'add on' into any other hydrogen coil.
Genetic algorithms and method of moments (GA/MoM): A novel integration for antenna design (2002)

This paper introduces a novel technique for efficiently integrating genetic algorithms with method of moments (GA/MoM) for antenna design and related electromagnetic problems through the application of direct Z-matrix manipulation (DMM). In the DMM approach to GA/MoM a mother impedance or Z-matrix is filled only once at the beginning of the optimization process, and then the GA optimizer operates on subsets of the original mother Z-matrix to perform the optimization. Application of DMM to the GA/MoM significantly reduces the total optimization time by eliminating multiple Z-matrix fill operations. The DMM also facilitates the use of matrix partitioning and pre-solving to further reduce the optimization time in many practical cases.
Phosphate coupling agents for calcium carbonate filler (1982)

Phosphate coupling agents, i.e., alkyl dihydrogenphosphates containing functional groups such as olefinic, chloro, methacryloxy, and mercapto, were synthesized and allowed to react with calcium carbonate filler suspended in an aqueous medium. The modification provided the filler with good dispersibility in mineral oil. Physical properties of the vulcanized rubbers loaded with the modified fillers were found to be influenced by the functional group introduced. For example, in peroxidecured ethylene–propylene–diene rubber (EPDM), the methacryloxy group was most effective, and the mercapto group significantly enhanced the physical properties of sulfur-cured styrene–butadiene rubber (SBR), while a saturated aliphatic phosphate was ineffective in both curing systems. Deposition of the coupling agent as calcium salt onto calcium carbonate surface was observed by scanning electron micrography. The novel approach for the surface modification of calcium carbonate filler is descussed in relation to the reinforcing effects on rubbery materials.
<title>Strict integrity control of biomedical images</title> (2001)

The control of the integrity and authentication of medical images is becoming ever more important within the Medical Information Systems (MIS). The intra- and interhospital exchange of images, such as in the PACS (Picture Archiving and Communication Systems), and the ease of copying, manipulation and distribution of images have brought forth the security aspects. In this paper we focus on the role of watermarking for MIS security and address the problem of integrity control of medical images. We discuss alternative schemes to extract verification signatures and compare their tamper detection performance.
Electric polarization in crystals and its response to thermal and elastic perturbations (1991)

Abstract The basic properties of electric polarization response in crystalline dielectrics are theoretically analysed. Spontaneous polarization, pyroelectricity, piezoelectricity, flexoelectricity (polarization response to strain gradient) and thermopolarization effect (polarization response to temperature gradient) are discussed on the basis of a unified approach. Special attention is paid to the problem of the adequate theoretical definition of these phenomena. The effect of the sample termination on the polarization response is considered in detail. Key Words: Electric polarizationthermal perturbationselastic perturbationsdielectrics
On the influence of electricity demand patterns, battery storage and PV system design on PV self-consumption and grid interaction (2016)

New policies supporting photovoltaics (PV) self-consumption and reduced feed-in power flows are advocated in many countries. Consequently, knowledge about the influences of demand patterns and battery energy storage on PV self-consumption and grid impact is required. This study analysed these influences for 400 residential and 26 commercial systems from the Netherlands. Results show larger self-consumption rates for commercial systems than residential systems. Batteries increase the self-consumption rate depending on the PV size and the battery size. Averaged curtailment losses are larger for residential systems than commercial systems and decrease with the addition of a battery to the system.
An AES-Based Encryption Algorithm with Shuffling. (2009)

The Syntax score has been established as a tool to determine the complexity of coronary artery disease and as a guide for decision-making among coronary artery bypass surgery and percutaneous coronary intervention. The purpose of this review is to systematically examine what the Syntax score is, and how the surgeon should integrate the information in the selection and treatment of patients. We reviewed the results of the SYNTAX Trial, the clinical practice guidelines, as well as the benefits and limitations of the score. Finally we discuss the future directions of the Syntax score.
Experimental Realization of Quantum-Resonance Ratchets at Arbitrary Quasimomenta (2008)

Quantum-resonance ratchets associated with the kicked particle are experimentally realized for arbitrary quasimomentum using a Bose-Einstein condensate (BEC) exposed to a pulsed standing light wave. The ratchet effect for general quasimomentum arises even though both the standing-wave potential and the initial state of the BEC have a point symmetry. The experimental results agree well with theoretical ones which take into account the finite quasimomentum width of the BEC. In particular, this width is shown to cause a suppression of the ratchet acceleration for exactly resonant quasimomentum, leading to a saturation of the directed current.