gebhart/patrepeval huggingface dataset:
Evidence for transsynaptic regulation of calmodulin-dependent cyclic nucleotide phosphodiesterase in cerebellar Purkinje cells (1989)

Calmodulin-dependent phosphodiesterase (CaM-PDE) is selectively expressed in specific neuronal populations in adult rat brain. In cerebellar cortex, it is expressed at high levels in Purkinje cells (soma and dendrites). Climbing fiber ablation by intraperitoneal injections of 3-acetylpyridine resulted in a selective depression of cerebellar CaM-PDE expression using Western immunoblot procedures; neither calcineurin (calmodulin-dependent protein phosphatase) nor other calmodulin binding proteins, detected by biotinylated calmodulin overlays, were affected. Immunocytochemical staining of cerebellum revealed a loss of detectable CaM-PDE immunoreactivity in Purkinje cells, with no appreciable change in calcineurin immunoreactivity. Cerebral cortex was examined as a control for a direct effect of 3-acetylpyridine on CaM-PDE expression, independent of climbing fiber deafferentation. There were no detectable changes in CaM-PDE or calcineurin immunoreactivity in cortical pyramidal cells, and no changes were detected, either in Western blot analyses for CaM-PDE or calcineurin or in biotinylated calmodulin overlays. These data suggest that CaM-PDE expression in Purkinje cells is regulated transsynaptically by climbing fiber inputs.
A Comparison of Respiratory Symptoms and Inflammation in Sudden Infant Death Syndrome and in Accidental or Inflicted Infant Death (2003)

Upper respiratory infection and pulmonary inflammation are common in sudden infant death syndrome, but their role in the cause of death remains controversial. Controlled studies comparing clinical upper respiratory infection and inflammation in sudden infant death syndrome with sudden infant deaths caused by accidents and inflicted injuries (controls) are unavailable. Our aim was to compare respiratory inflammation and upper respiratory infection within 48 hours of death and postmortem culture results in these two groups. A retrospective analysis of upper respiratory infection and pathologic variables in the trachea and lung of 155 infants dying of sudden infant death syndrome and 33 control infants was undertaken. Upper respiratory infection was present in 39% of sudden infant death syndrome cases and 40% of control cases. Upper respiratory infection was more likely to have occurred in association with more severe lymphocytic interstitial pneumonitis when sudden infant death syndrome cases and control cases were combined ( P=.04). Proximal and distal tracheal lymphocytic infiltration was more severe in control cases than in sudden infant death syndrome cases ( P=.01 and.01, respectively). Lymphocytic infiltrations of the bronchi, bronchioles, and pulmonary interstitium were similar between groups. Bronchial associated lymphoid tissue was more prominent in control cases ( P=.04). Cultures were positive in 80% of sudden infant death syndrome cases, 78% of which were polymicrobial. Among control cases, 89% were positive, with 94% being polymicrobial. This study confirms that microscopic inflammatory infiltrates in sudden infant death syndrome are not lethal.
Nonlinear Few‐Layer Antimonene‐Based All‐Optical Signal Processing: Ultrafast Optical Switching and High‐Speed Wavelength Conversion (2018)

Abstract Exploration of ultrastable 2D material‐based optical devices toward all‐optical signal processing is attracting rising interest. As a Group‐VA monoelemental 2D material, antimonene is becoming a promising nonlinear optical material owing to its outstanding optoelectronic advantages with long‐term stability. Herein, all‐optical signal processing based on the high optical nonlinearity of antimonene is first demonstrated. Few‐layer antimonene is fabricated and decorated on the microfiber as an optical device. The device can be applied as an all‐optical Kerr switcher with an extinction ratio as high as ≈12 dB and wavelength conversion of modulated high‐speed signals at a frequency up to 18 GHz. The findings indicate that such a few‐layer antimonene‐based photonics device is applicable in nonlinear optics, which can be potentially developed for the applications of next‐generation high‐speed optical communication.
A Survey on Patient Queue Management System (2018)

In this paper, we study the various types of Queue and Queue Management System.Queue system can successfully reduce waiting time of the patients in the hospitals.We aim to implement a model that initializes alert notification via SMS to patients of a hospital.It will minimize the queue of patients in the waiting area of hospital and also patient can book an appointment from anywhere at a given time.Patients can book an appointment via android application.and accordingly patients and also it will provide navigation towards that nearest hospital.Hence, for developing such a model a survey has been done on various types of queues.
METRO: a router architecture for high-performance, short-haul routing networks (1994)

The Multipath Enhanced Transit Router Organization (METRO) is a flexible routing architecture for high-performance, tightly-coupled, multiprocessors and routing hubs. A METRO router is a dilated cross-bar routing component supporting half-duplex bidirectional, pipelined, circuit-switched connections. Each METRO router is self-routing and supports dynamic message traffic. The routers works in conjunction with source-responsible network interfaces to achieve reliable end-to-end data transmission in the presence of heavy network congestion and dynamic faults. METRO separates the fundamental architectural characteristics from implementation parameters. Simplicity of routing function coupled with freedom in the implementation parameters allows METRO implementations fully exploit available technology to achieve low-latency and high-bandwidth. We illustrate the effects of this implementation freedom by summarizing the performance which various METRO configurations can extract from some modern CMOS technologies. Included in our illustrations is METROJR-ORBIT, a minimal instance of the METRO architecture we constructed in a 1.2μ gate-array technology.
Effects of gamma radiation on some physical properties of polytetrafluoroethylene resin (1959)

Abstract Effects of gamma radiation on the properties, such as melt viscosity, elastic modulus above the melting point, creep fracture time above the melting point, density, and the degree of crystallinity by x‐ray diffraction, of polytetrafluoroethylene resin were studied. When exposed to the radiation from a Co 60 gamma source, the melt viscosity falls rapidly with increasing radiation dose above 10 4 roentgens, and the rubber elasticity above the melting point decreases with increasing irradiation. Also, Zero Strength Time (a creep fracture time test) above the melting point decreases rapidly with irradiation above 10 3 roentgens; this behavior is attributable to the chain scission and the accompanying decrease in average molecular weight. Density was found to increase with radiation dose at doses higher than 10 4 roentgens; also, at 2θ = 18° peak in the X‐ray diffraction pattern, which is indicative of crystallinity, increases slightly in sharpness with irradiation. These facts suggest that gamma irradiation of this polymer produces chain scission and decreases the average molecular weight, and also causes partial crystallization followed by an increase in the density in the amorphous region. Therefore, crosslinking would probably be negligible in this polymer.
<b>Stable Carbonium Ions. II.</b><sup>1a</sup> <b>Oxocarbonium</b><sup>1b</sup> <b>(Acylium) Tetrafluoroborates, Hexafluorophosphates, Hexafluoroantimonates and Hexafluoroarsenates. Structure and Chemical Reactivity of Acyl Fluoride: Lewis Acid Fluoride Complexes</b><sup>1c</sup> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStable Carbonium Ions. II.1aOxocarbonium1b(Acylium) Tetrafluoroborates, Hexafluorophosphates, Hexafluoroantimonates and Hexafluoroarsenates. Structure and Chemical Reactivity of Acyl Fluoride: Lewis Acid Fluoride Complexes1cGeorge A. Olah, Stephen J. Kuhn, William S. Tolgyesi, and Edward B. BakerCite this: J. Am. Chem. Soc. 1962, 84, 14, 2733–2740Publication Date (Print):July 1, 1962Publication History Published online1 May 2002Published inissue 1 July 1962https://pubs.acs.org/doi/10.1021/ja00873a019https://doi.org/10.1021/ja00873a019research-articleACS PublicationsRequest reuse permissionsArticle Views1155Altmetric-Citations148LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
LAS CASES: <i>MÉMORIAL DE SAINTE-HÉLÈNE</i> (1951)

LAS CASES: MÉMORIAL DE SAINTE-HÉLÈNE: A COMMENTARY ON DOCUMENTS RELATIVE TO THIS WORK IN THE BRITISH MUSEUM Get access F. G. HEALEY F. G. HEALEY BIRMINGHAM Search for other works by this author on: Oxford Academic Google Scholar French Studies, Volume V, Issue 1, January 1951, Pages 18–29, https://doi.org/10.1093/fs/V.1.18 Published: 01 January 1951
Improving LZW (data compression algorithm) (2002)

The Lempel-Ziv-Welch compression algorithm is widely used because it achieves an excellent compromise between compression performance and speed of execution. A simple way to improve the compression without significantly degrading its speed is proposed, and experimental data show that it works in practice. Even better results are achieved with additional optimization of 'phasing in' binary numbers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
ATM status confers sensitivity to arsenic cytotoxic effects (2001)

Arsenic (As), a human carcinogen, represents a worldwide health problem due to the high number of people exposed to this element in their drinking water. Previously our group has demonstrated that As can impair lymphocyte cell proliferation in vitro and in vivo and can increase the level of P53 protein, with different responses to these effects between individuals. Recently it has been shown that ATM protein, responsible for the autosomal recessive disorder ataxia telangiectasia (AT), regulates P53. In this study the induced response of P53 was evaluated following exposure to As in human lymphoblastoid cell lines normal (+/+), heterozygous (+/-) or homozygous (-/-) for the mutant ATM gene. After 24 h As treatment we found a dose-dependent induction of P53 in normal and heterozygous cell lines, although differences between cell lines were observed. An increase in P21(WAF) protein, a main effector of P53 activation, was also observed in the same cell lines. In contrast, neither P53 nor P21 induction was detected in homozygous cells. The ATM (+/-) and (-/-) genotypes confer more sensitivity to As cytotoxic effects than the normal allelic condition. Paradoxically, ATM heterozygous cells were more sensitive to As, leading us to propose that this might be related to activation of apoptosis and removal of non-repairable cells. In contrast, in AT cells in which ATM is absent or mutated activation of P53 and its target genes is abrogated, allowing cells to replicate with damage in the presence of As, with cell death ensuing by a pathway different from P53.
Pathology of Experimental Compression Neuropathy Producing Hyperesthesia (1993)

An experimental neuropathy in rats produced by tying loosely constrictive ligatures around one sciatic nerve has recently been shown to produce pain-related behavior that follows a reproducible time course. In the present study, we assessed the degree of thermal hyperesthesia and examined the sciatic nerves by light and electron microscopy at different time points from 1 day to 12 weeks after surgery. Edema was the initial pathologic change seen in the neuropathy and was associated with early Wallerian degeneration on day 1. Injury to the connective tissue sheaths with interruption of the perineurial layer, infiltration of macrophages into the endoneurium, and proliferation of endothelial cells were observed during the first week. Endothelial cells hypertrophied and changed to a rhomboid shape with gaps between adjacent cells. Most large myelinated and many small myelinated fibers underwent Wallerian degeneration. Unmyelinated fiber numbers were reduced to one-third of the normal value from day 5 to day 14. Axonal sprouts were numerous after 1 week and grew into the segment distal to the ligatures by 4 weeks. Aberrant sprouts in minifascicles outside the perineurium were present from 4 weeks on. The original ligatures were rapidly surrounded by large amounts of fibrous tissue and mostly absorbed by 12 weeks; the initial fascicular compression caused by the ligatures was maintained by the fibrous tissue. We conclude that, whereas neuroma formation may contribute to the pain-related behavior in the later stages of this neuropathy, acute changes in the endoneurial microenvironment are important for its initial development.
Olefin Isomerization and Hydrosilylation Catalysis by Lewis Acidic Organofluorophosphonium Salts (2013)

Organofluorophosphonium salts of the formula [(C6F5)(3-x)Ph(x)PF][B(C6F5)4] (x = 0, 1) exhibit Lewis acidity derived from a low-lying σ* orbital at P opposite F. This acidity is evidenced by the reactions of these salts with olefins, which catalyze the rapid isomerization of 1-hexene to 2-hexene, the cationic polymerization of isobutylene, and the Friedel-Crafts-type dimerization of 1,1-diphenylethylene. In the presence of hydrosilanes, olefins and alkynes undergo efficient hydrosilylation catalysis to the alkylsilanes. Experimental and computational considerations of the mechanism are consistent with the sequential activation and 1,2-addition of hydrosilane across the unsaturated C-C bonds.
Architecting noncooperative networks (1995)

In noncooperative networks users make control decisions that optimize their individual performance measure. Focusing on routing, two methodologies for architecting noncooperative networks are devised, that improve the overall network performance. These methodologies are motivated by problem settings arising in the provisioning and the run time phases of the network. For either phase, Nash equilibria characterize the operating point of the network. The goal in the provisioning phase is to allocate link capacities that lead to systemwide efficient Nash equilibria. The solution of such design problems is, in general, counterintuitive, since adding link capacity might lead to degradation of user performance. For systems of parallel links, it is shown that such paradoxes cannot occur and that the optimal solution coincides with the solution in the single-user case. Extensions to general network topologies are derived. During the run time phase, a manager controls the routing of part of the network flow. The manager is aware of the noncooperative behavior of the users and makes its routing decisions based on this information while aiming at improving the overall system performance. We obtain necessary and sufficient conditions for enforcing an equilibrium that coincides with the global network optimum, and indicate that these conditions are met in many cases of interest.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Optimization of personal distribution for evacuation guidance based on vector field (2011)

It is an important issue to make a disaster reduction plans for overcrowded population in the urban cities. In this paper, we focus on evacuation guidance to prevent the damage from spreading. The personal navigation system cannot deal with evacuation guidance for the human crowd with large numbers of individuals because of time constraints and extraordinary communication error. An implicit guidance based on dynamical characteristic of swarm behavior is efficient and effective with a few guidance operators. We propose a modeling and control method of swarm based on vector field. The evacuee behavior model contains intention of evacuation, field of view, collision avoidance and evacuee group, which are represented by vector field. The guidance operator model contains indicating direction. By giving the desired vector field that indicates the safe route for evacuation, the position of guidance operators are optimally distributed. Moreover, the number of guidance operators is minimized based on the contribution index. The proposed modeling and control method is applied to the swarm robot and the effectiveness is evaluated by the experiments.
Synthetic corneal inlays (2007)

This review is based on the activities of the Vision Cooperative Research Centre (previously Cooperative Research Centre for Eye Research and Technology) Corneal Implant team from 1991 to 2007. The development of a synthetic polymer of perfluoropolyether (PFPE), meeting essential physical and biological requirements, for use as a corneal inlay is presented. Each inlay was placed in a corneal flap created with a microkeratome and monitored over a two-year period in a rabbit model. The results indicate that the PFPE implant shows excellent biocompatibility and biostability. As a result, a Phase 1 clinical trial is being conducted. Three years post-implantation, the PFPE inlays are exhibiting continued excellent biocompatibility. Corneal inlays made from PFPE are biocompatible with corneal tissue in the long term and offer a safe and biologically-acceptable alternative to other forms of refractive surgery.
The place for rapid‐acting insulins in therapy (2015)

Steve Chaplin and Professor Stephen Bain provide an overview of the properties of rapid‐acting insulins and their place in the management of diabetes
Mode of antiviral action of silver nanoparticles against HIV-1 (2010)

These properties make them a broad-spectrum agent not prone to inducing resistance that could be used preventively against a wide variety of circulating HIV-1 strains.
Magnetic Field Sensor and Its Application to Automobiles (1980)

<div class="htmlview paragraph">A direction sensor, which measures the terrestrial magnetism and its application to automobiles are discussed. The flux gate type sensor proposed in this paper is sensitive and stable enough for automotive use. A new technique to compensate the car body magnetism is also discussed. The heading display system which consists of a direction sensor, a control circuit and a display device works quite well. A Trip Computer with more attractive features can be easily embodied by applying this sensor.</div>
A New Continuous Guidance Tool Used for High Accuracy Directional Surveys (1981)

ABSTRACT In recent years, it has become increasingly important to determine, with a high degree of precision, the bottom hole location and trajectory of a well. Optimum reservoir drainage from deviated wells drilled from a single platform; successful relief well positioning for blowouts; and the demands made to comply with ecological or environmental conservation, all depend on a high level of accuracy in measuring the geometric parameters of boreholes. The Guidance Continuous (GCT*) Tool has been built to fill this need. It is a 92 mm diameter cased hole tool equipped with the most advanced guidance components on the market. Comparison tests have shown it to at least an order of magnitude better than similar guidance systems. Computations of the well trajectory are carried out by real-time software and the CSU" surface computer can be used to generate all the required listings, plots and projections of the well in given planes. The gyroscope central to the device is mounted on a motorized inertial platform allowing two degrees of freedom and giving very high overall accuracy. Quality control features such as the "closure" - the horizontal distance between the starting point of the survey and the final point, at the same depth, on the return survey - are an integral part of the design. Finally, the GCT tool is self-calibrating and needs no preset geographical references.
Isolation and Characterization of a Boron-Polysaccharide Complex from Radish Roots<xref ref-type="fn" rid="fn1"><sup>1</sup></xref> (1993)

A boron-polysaccharide complex was purified from a Driselase digest of cell walls of radish roots. The complex had a molecular weight of 7.5 KDa and contained boron (0.232%, w/w), uronic acid (52.3%, w/w) and neutral sugars (32.4%). 11B-NMR spectroscopic analysis suggested that the boron was present as a tetravalent 1 : 2 borate-diol complex.
FBMTP: An Automated Fault and Behavioral Anomaly Detection and Isolation Tool for PLC-Controlled Manufacturing Systems (2016)

The fault and behavioral anomaly detection and isolation (FBADI) in programmable logic controller (PLC) controlled systems has been under an active study for several decades. In this paper, we present a tool, called the fault and behavior monitoring tool for PLC (FBMTP) that can solve the FBADI problem in PLC-controlled manufacturing systems effectively. FBMTP first creates a nominal deterministic finite-state automaton-based model of the PLC control process, and then utilizes that model to detect and isolate the faults and the behavioral anomalies. The key idea is to check whether the observed behavior is consistent with the modeled behavior or not. The control signal data stored in the PLC memory is used for this whole procedure. With growing size of the manufacturing systems, it becomes difficult to obtain all the control signal data accurately because of the limited data acquisition time in each PLC scan cycle. The proposed control process modeling and the FBADI methodology of FBMTP can cope with such data inaccuracy problems associated with large manufacturing systems efficiently. Our experiments show that FBMTP provides highly accurate FBADI results for both small and large manufacturing systems.
The Quality of Osteolysis Grafting with Cementless Acetabular Component Retention (2007)

Periprosthetic osteolysis is a common cause for revision of total hip arthroplasty. When modular cementless acetabular components are stable, curettage and grafting of the osteo-lytic lesion while retaining the component are a good surgical option. Although the midterm outcome of this procedure is known, the quality of the surgical technique is not. We used preoperative and postoperative computed tomography to determine the percentage of periacetabular lesions that was grafted and the percentage of the lesion volume filled with an injectable bone graft substitute. We discovered, even with preoperative computed tomography reconstructions and surgical planning, four of 22 lesions were neglected at the time of surgery. In the 18 lesions that were treated, we were able to fill an average of 49% (range, 0-83%) of the lesion volume. These inconsistent results illustrate a need to further refine surgical techniques and instrumentation to treat one of the most common complications in total hip arthroplasty. Longer followup with repeat computed tomography scans or other imaging techniques would determine if the percentage of lesion fill has an effect on clinical outcome.