gebhart/patrepeval huggingface dataset:
Improving main agronomic characters of dihaploids with 2n gametes by means of sexual hybridisation and anther culture of potato ( <i>Solarium tuberosum</i> ) (2000)

Abstract Three hybrid populations were obtained from 4x‐2.x, 2x‐4x, and 2x‐2x crosses by using two tetraploids ( Solanum tuberosum L.) and three dip‐loid hybrids of closely related species which can produce 2n gametes. Forty‐three dihaploid plantlets were regenerated from embryoids of anthers of the three tetraploid hybrids by anther culture in vitro. Three of them could produce 2n pollen and five of them could produce 2n eggs. The morphological and agronomic characters of these dihaploids with 2n gametes were compared with those of their diploid and tetraploid parents. Two dihaploid clones with 2n gametes and improved agronomic characters were obtained. The results suggest that ploidy manipulation through sexual polyploidisation and dihaploid induction by anther culture is an effective method to obtain dihaploid clones with 2n gametes in combination with good tuber yield and tuber appearance in potato.
Passivity-Based Stability Assessment of Grid-Connected VSCs—An Overview (2015)

The interconnection stability of a grid-connected voltage-source converter (VSC) can be assessed by the passivity properties of the VSC input admittance. If critical grid resonances fall within regions where the input admittance acts passively, i.e., has nonnegative real part, then their destabilization is generally prevented. This paper presents an overview of passivity-based stability assessment, including techniques for space-vector modeling of VSCs whereby expressions for the input admittance can be derived. Design recommendations for minimizing the negative-real-part region are given as well.
Salud mental y educación para la salud:: propuesta para un dispositivo de internamiento breve (2014)

espanolLa educacion para la salud constituye una de las funciones basicas del equipo de salud publica cuyo objetivo procura ensenar la forma de vida saludable, fomentar y recuperar la salud e insertarse adecuadamente en su medio (familiar o social). Este procedimiento es un proceso que se lleva a cabo mediante el acto de comunicar, en la que el transmisor lo constituye la enfermera, el receptor tanto el individuo como la comunidad y el mensaje esta formado por los contenidos y las herramientas fomentadoras del autocuidado. Dentro del equipo multidisciplinar, la enfermera de salud mental es la profesional del equipo que mas esta en contacto con la comunidad y por ello conoce a fondo a la poblacion y sus necesidades individuales o colectivas para llevar a cabo una adecuada educacion para la salud. Con este trabajo se pretende aportar una serie de actividades formativas dentro de este campo articuladas a partir de los patrones de Marjory Gordon, con los que se persigue que el individuo o la colectividad asuman competencias en lo referente a su autocuidado. Este sistema clasificatorio define 11 patrones patrones de actuacion relevantes para la salud de las personas, las familias y las comunidades, donde se tratan configuraciones de comportamientos, mas o menos comunes a todas las personas, que contribuyen a su salud, calidad de vida y al logro de su potencial humano. Pese a ello, las actuaciones se orientan y enfocan hacia las actividades formativas que se desarrollan en una unidad de internamiento breve de psiquiatria. EnglishEducation for health is one of the basic functions of public health team whose goal strives to teach healthy lifestyle, promote and restore health and inserted properly in their environment (family or social). This procedure is a process carried out by the act of communicating, which is the transmitter as a nurse, receiving both the individual and the community and the message is made up of content and tools of self-promoting. Within the multidisciplinary team, mental health nurse is the professional team that is in contact with the community and so thoroughly known to the population and individual or group needs to carry out adequate health education. This paper seeks to provide a series of training activities articulated in this field from Gordon Marjory patterns, with which it pursues the individual or the community to assume responsibilities in relation to self-care. This classification system defines 11 patterns of activity patterns relevant to the health of individuals, families and communities, which treat behavioral configurations, more or less common to all people, that contribute to their health, quality of life and achievement of human potential. Nevertheless, the actions are oriented and focus to the training activities are developed in a short inpatient unit psychiatry.
Continuous monitoring of free fatty acid release from adipocytes by pH-stat titration. (1979)

A methods for direct and continuous monitoring of free fatty acid release in adipocyte suspensions is described. Using a pH-stat apparatus the protons from the released free fatty acids are continuously titrated and the accumulated amount of OH- added is monitored on a recorder against time, the slope thus indicating the rate of free fatty acid release. Sinc pH is kept constant, an incubation medium with a low buffering capacity can be used, which gives the method a high sensitivity. Under the conditions described, free fatty acid release from 5% of maximal norepinephrine stumulation of rat adipocytes can be accurately measured and the kinetics can be followed over extended periods of time.
Overtime Work, Overtime Compensation and the Distribution of Economic Well-Being: Evidence for West Germany and Great Britain (2001)

Using panel data for West Germany and Great Britain, we show that there are striking differences in overtime work and overtime compensation in the two countries in the 1990s. Our estimates reveal that the observed overtime patterns affect both the evolution of the monthly labour earnings distribution and individual economic well-being differently in West Germany and Great Britain. Besides varying labour market institutions in the two countries a higher incidence of a combination of performance-related pay and unpaid overtime in Great Britain is an important factor in explaining the observed differences. With regards to West Germany, we show that the current policy of transforming paid overtime in “working time accounts”, which is conducted in the spirit of “work-sharing”, is neither beneficial for employed workers in terms of income mobility, nor in terms of overall job satisfaction nor in terms of working time preferences.
Amine oxidase substrates mimic several of the insulin effects on adipocyte differentiation in 3T3 F442A cells (2001)

We have previously reported that substrates of monoamine oxidase (MAO) and semicarbazide-sensitive amine oxidase (SSAO) exert short-term insulin-like effects in rat adipocytes, such as stimulation of glucose transport. In the present work, we studied whether these substrates could also mimic long-term actions of insulin. Adipose differentiation of 3T3 F442A cells, which is highly insulin-dependent, served as a model to test the effects of sustained administration of amine oxidase substrates. Daily treatment of confluent cells with 0.75mM tyramine (a substrate of MAO and SSAO) or benzylamine (a substrate of SSAO) over 1 week caused the acquisition of typical adipocyte morphology. The stimulation of protein synthesis and triacylglycerol accumulation caused by tyramine or benzylamine reached one half of that promoted by insulin. This effect was insensitive to pargyline (an MAO inhibitor), but was inhibited by semicarbazide (an SSAO inhibitor) and by N-acetylcysteine (an antioxidant agent), suggesting the involvement of the H2O2 generated during SSAO-dependent amine oxidation. Chronic administration of amine oxidase substrates also induced the emergence of adipose conversion markers, such as aP2, glycerol-3-phosphate dehydrogenase, the glucose transporter GLUT4, and SSAO itself. Moreover, cells treated with amines acquired the same insulin sensitivity regarding glucose transport as adipocytes classically differentiated with insulin. In all, most of the adipogenic effects of amines were additive to insulin. Our data reveal that amine oxidase substrates partially mimic the adipogenic effect of insulin in cultured preadipocytes. Furthermore, they suggest that SSAO not only represents a novel late marker of adipogenesis, but could also be directly involved in the triggering of terminal adipocyte differentiation.
Separation of bulk hydrogen sulfide–hydrogen mixtures by selective surface flow membrane (1997)

Abstract The separation performance of binary hydrogen sulfide–hydrogen mixtures by a nanoporous carbon membrane called selective surface flow (SSF) membrane is described. The membrane selectively permeates H 2 S from H 2 , and a H 2 ‐enriched stream is produced at the feed‐gas pressure. A two‐stage embodiment of the SSF membrane is described for production of high‐purity H 2 with high H 2 recovery from an equimolar H 2 S‐H 2 feed gas. A novel protocol for operation of the two‐stage membrane is needed to achieve that separation goal.
An Anomaly Detector Deployment Awareness Detection Framework Based on Multi-Dimensional Resources Balancing in Cloud Platform (2018)

Anomaly detection has been an important topic in cloud platforms to guarantee the dependability and robustness of services in the cloud. Most research works were proposed to tackle the detection performance problems of detection algorithms caused by the volume of data, the dynamic environment, various types of anomalies, and so on. However, almost all of them take only the optimization of algorithms into account, which leads to a situation that some key features of detector deployment and the scalability and dependability of the detection framework itself are omitted. Therefore, an anomaly detector deployment awareness detection framework based on multi-dimensional resources balance is proposed to address the problems. It balances the multi-dimensional resources by bringing four factors of resources into consideration to deploy detectors quietly, which are the current utilizations, the available capacity, the demands of detectors and the remaining resources. Three experiments and comparative analysis suggest that this framework achieves a higher scalability and detection accuracy than the existing framework.
Kinetic Study of the Dynamic Behavior of [M(C<sub>6</sub>F<sub>5</sub>)X(OPPy<sub><i>n</i></sub>Ph<sub>3-<i>n</i></sub>)] (M = Pd, Pt; X = C<sub>6</sub>F<sub>5</sub>, Halide; <i>n</i> = 1−3):  Activation Parameters for the Restricted Rotation about the M−Aryl Bond and for the Py Associative Exchange (1997)

The behavior in CDCl3 of complexes of the type [M(C6F5)X(OPPynPh3-n)] (M = Pd, Pt; X = C6F5; halide; n = 1−3) has been studied by 19F and 1H NMR spectroscopy. For the nonplanar N,N-chelating ligands with n = 2, 3, two processes have been observed and their activation parameters, ΔG⧧, ΔH⧧, and ΔS⧧, have been determined, using magnetization transfer (MT) or line-shape analysis methods. The rotation of the C6F5 groups about the M−Cipso bond occurs in the square-planar species without dissociation, and its rate depends on the size of the coordinated atom X, in the order C6F5 > Cl > Br > I. The rotation for the last three is very slow and is detected only by MT. With OPPy3 the occurrence of associative exchange of free and coordinated Py groups is observed (studied only for X = C6F5, Cl), the rate depending on M and X in the order Pd > Pt and Cl > C6F5. Only for [Pd(C6F5)Cl(OPPy3)] is this rate faster than the C6F5 rotation, producing the effect of an apparent rotation with anomalously low activation parameter...
Soluble Guanylyl Cyclase: Physiological Role as an NO Receptor and the Potential Molecular Target for Therapeutic Application (2003)

Nitric oxide (NO) activates soluble guanylyl cyclase, which results in an increased synthesis of cyclic guanosine 3',5'-cyclic monophosphate (cGMP), smooth muscle relaxation and vasodilation. The heme group in soluble guanylyl cyclase binds NO and allosterically activates the catalytic site. In addition, a second allosteric site that synergistically activates the enzyme has been reported. BAY 41-2272 was reported as an NO-independent activator of soluble guanylyl cyclase. Treatment with this compound results in anti-platelet activity, a decrease in blood pressure and an increase in survival, indicating a potential for treating cardiovascular diseases. YC-1, another NO-independent activator, activates soluble guanylyl cyclase and the activity is enhanced in the presence of NO. YC-1 relaxed tissue strips in organ bath. Consistent with its biochemical activity, YC-1 induced penile erection in a conscious rat model. Recently, we found a novel series of soluble guanylyl cyclase activators that also NO-independently activate soluble guanylyl cyclase and cause penile erection, suggesting a synergy with the endogenous NO production in vivo. Here I review the NO/cGMP signal transduction pathway and define soluble guanylyl cyclase modulators as a novel approach for the treatment of cardiovascular diseases and erectile dysfunction.
Identification of a calcium-binding protein as a calcium-dependent regulator of brain adenylate cyclase. (1975)

An activating factor of adenylate cyclase (EC 4.6.1.1) HAS BEEN OBTAINED FROM DETERGENT-DISPERSED PREPARATIONS OF PORCINE CEREBRAL CORTEX BY COLUMN CHROMATOGRAPHY ON ECTEOLA-cellulose. The factor was identified by acrylamide gel electrophoresis and by enzyme activation studies as the Ca2+-binding protein that regulates the activity of a brain cyclic nucleotide phosphodiesterase. This Ca2+-binding protein confers a Ca2+-dependent activation upon the adenylate cyclase, which is reversed by the subsequent addition of egta in excess of the free Ca2+. It is proposed that this Ca2+-dependent regulator controls enzymatic activities responsible for the synthesis of adenosine 3':5'-monophosphate and for the hydrolysis of guanosine 3':5'-monophosphate.
Progressive Supranuclear Palsy: A Review of Co-existing Neurodegeneration (2008)

As in previous studies, this study has demonstrated the frequent co-existence of pathological changes usually noted in other neurodegenerative diseases in PSP. Whether these co-existing pathological changes contribute to the cognitive impairment in PSP remains uncertain.
CROSS-CULTURAL ASSESSMENT OF NEUROPSYCHOLOGICAL PERFORMANCE AND ELECTRICAL BRAIN FUNCTION MEASURES: ADDITIONAL VALIDATION OF AN INTERNATIONAL BRAIN DATABASE (2007)

Previous studies have revealed significant differences in performance on nonlanguage dependent cognitive tests across international settings among younger individuals, with less pronounced differences evident among older individuals (>54 years of age). The present study examined a broad range of cognitive performance as well as electrophysiological indices of brain function in a multisite and international context. A total of 200 individuals in the United States, 233 individuals in Europe, and 829 individuals in Australia were administered a standardized computerized neuropsychological battery, and complementary electroencephalogram (EEG) recordings were completed. Results revealed no significant differences in cognitive function or electrophysiology across the three continents. Similarly, although there was a main effect for age, the interaction between age and continent was not significant in any of the omnibus analyses. These findings indicate a high degree of similarity in neurocognitive and electrophysiological function among individuals residing in developed Western cultures, consistent with a traitlike status and the high heritability of the EEG.
Nanostructured electrochromic films by inkjet printing on large area and flexible transparent silver electrodes (2014)

Printed electrochromic flexible films were obtained by combining transparent silver grid electrodes formed by self-assembly and inkjet printed WO3 nanoparticles. Concentrated dispersions of WO3 nanoparticles were inkjet printed on transparent plastic silver grid electrodes with a high transparency of 83% in the spectral range of 400-800 nm, and a low sheet resistance in the range of 1-5 Ω sq(-1). These electrodes were used for electrochromic applications for the first time. The resultant patterned nanostructured electrochromic films maintained their coloring and bleaching performance after bending of the flexible films.
Remembering one's identity: the epigenetic basis of stem cell fate decisions (2011)

Stem cells serve a vital role in multicellular organisms by constantly replenishing tissue with their differentiated progeny during normal homeostasis or damage. How these cells maintain their identities throughout the life of an organism is an area of intense research. In this review, we explore recent emerging evidence that stem cell fate decisions are based on their epigenome and specific epigenetic factors.
Bausteine von Oligosacchariden, CIII. Synthese von modifizierten Derivaten des Disaccharides β‐<scp>D</scp>‐Gal‐(1 → 3)‐α‐<scp>D</scp>‐GalNAc zur Untersuchung der Substratspezifität der Core‐2‐β6‐GlcNAc‐Transferase und α‐3‐Sialyltransferase der Biosynthese von <i>O</i>‐Glycoproteinen (1992)

Building Units of Oligosaccharides, CIII. — Synthesis of Modified Derivatives of the Disaccharide β‐ D ‐Gal‐(→3)‐α‐ D ‐GalNAc for the Examination of Substrate Specificities of Core 2‐β6‐GlcNAc‐Transferase and α‐3‐Sialyltransferase Involved in the Biosynthesis of O ‐Glycoproteins Derivatives of benzyl β‐ D ‐galactopyranosyl‐(1→3)‐2‐acet‐amido‐2‐deoxy‐α‐ D ‐galactopyranoside have been synthesized. The 6′‐, 4′‐ and 3′‐OH group of the galactose moiety as well as the 6‐ and 4‐OH and the 2‐acetamido group of the 2‐acet‐amido‐2‐deoxy‐ D ‐galactose moiety have been selectively substituted by the corresponding deoxy function. The compounds are useful in studies of the substrate specificities of the core 2‐β6‐GlcNAc‐transferase and the α3‐sialyltransferase involved in the biosynthesis of O ‐glycoproteins.
Selection of micro-acoustic technologies for the realization of single-ended / balanced WCDMA duplexers (2008)

With the increasing number of frequency bands for WCDMA applications, also the need for miniaturized duplexer solutions increases in order to realize multi-band, multi-mode mobile phones. With SAW and BAW, two well established micro-acoustic technologies are available. For the realization of competitive CDMA duplexers like for the US-PCS band, so far the focus has been mainly on the provision of resonators with high quality factors and reduced temperature coefficient of frequency to realize filters with highest guaranteed steepness of filter skirts. With the large variety of duplexer requirements in the new WCDMA bands and the trend towards single-ended / balanced operation in the RX path, the constraints for technology selection have somewhat changed. Only when considering all critical parameters like center frequency, TX-RX bandgap, filter bandwidth, and insertion attenuation requirements, individual technology solutions for the different WCDMA frequency bands can be identified in order to provide superior duplexer solutions with respect to cost, size, quality, and performance.
VCO Design With On-Chip Calibration System (2006)

This paper presents a low-supply voltage integrated CMOS voltage-controlled oscillator (VCO) with an on-chip digital VCO calibration control system. The VCO utilizes various state-of-the-art design methods to achieve low phase noise. The calibration system includes a novel high-speed digital divide by two circuit and a counter running on 1-GHz input to enable on-chip frequency measurement. An arithmetic unit and algorithms to perform the calibration are implemented using on-chip logic. Two different types of calibration methods have been implemented and measured in order to compare the proposed VCO gain optimization method with more conventional type of VCO calibration. The measurements show that the VCO design has phase noise from <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$-$</tex> 120.5 dBc/Hz to <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$-$</tex> 118.7 dBc/Hz @ 400-kHz offset, measured over the frequency range from 1.67 to 1.93 GHz. The proposed VCO gain optimization method is capable of reducing the <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$K_ VCO$</tex> peak-to-peak variation of the presented VCO design from 54.4% to 29.8% in DCS1800 and PCS1900 GSM transmission bands when compared to the conventional type of calibration method.
Phorbol ester and mitogens stimulate human fibroblast secretions of plasmin-activatable plasminogen activator and protease nexin, an antiactivator/antiplasmin. (1983)

Tumor-promoting phorbol esters have been reported to greatly increase plasminogen activator (PA) activity produced in numerous cell types. Many of these studies have employed a widely used fibrinolysis assay for PA activity that involves large-scale dilution of cell lysates or conditioned medium (CM) into buffer containing plasminogen and the plasmin substrate 125I-fibrin. This assay indicates that phorbol ester and the mitogens epidermal growth factor (EGF) and thrombin all stimulate secretion of PA activity in our human foreskin fibroblast cultures. However, these effects are not observed in a modified fibrinolysis assay employing undiluted conditioned culture medium unless the medium is first treated at pH 3, which inactivates the secreted protease inhibitor, protease nexin (PN). Moreover, a direct assay for plasminogen activator activity based on cleavage of 125I-plasminogen indicates that conditioned culture medium contains little if any active plasminogen activator either before or after treatment of the cultures with phorbol ester or EGF. Phorbol ester and mitogens do stimulate secretion of (a) an inactive PA that can be activated by plasmin and (b) PN, which inhibits both the activated form of the PA and plasmin. Secretions of the inactive PA and PN are further correlated in that release of both is stimulated most by phorbol ester, somewhat less by EGF, and least by thrombin. Significantly, these effects are not accompanied by increases in total protein secretion. We propose that fibroblasts secrete PA in an inactive form in the presence of PN to confine PA activity to an as yet undefined location or event.
Use of Fitness Facilities, Equipment, and Programs: A Case Study of a Japanese Fitness Club (1995)

This study examined the rates and patterns of use of the various facilities, equipment, and programs in a Yokohama fitness club. Analyses of the responses of 208 members (males = 98, females = 110) to a specially constructed questionnaire showed that the showers, sauna, bath, and Jacuzzi were the most often used facilities followed by aerobic exercise machines (e.g., exercise bikes and treadmills), the swimming pool, and machines for training the lower and upper body. In addition, four distinct and representative patterns of use of the facilities and equipment were identified. Swimming activities dominated Pattern A, and accordingly it was named the Swimming Pattern ( n =59). Pattern B, the Dance and Communication Pattern ( n = 15), was characterized by the use of the communication hall and coffee lounge and participation in aerobic dance. Pattern C, the Fashionable Pattern ( n = 4), consisted of participation in aerobic dance for men, 1-km swimming, and the use of the tanning corner and restaurant. Finally, Pattern D, the Machine Training Pattern ( n = 130), included the use of weights to train the upper and lower body. These results revealed an inefficient use of some of the facilities and equipment of the club. In addition to these findings, respondents preferred their supervisors to be friendly and expressed a desire for a larger swimming pool.