gebhart/patrepeval huggingface dataset:
A secure electronic medical record sharing mechanism in the cloud computing platform (2011)

Privacy is a very important issue when storing electronic medical records. According to the definition set out in the Health Insurance Portability and Accountability Act (HIPPA), the confidential section of the electronic medical record needs to be protected. Thus, a mechanism to protect the patient's privacy is needed during electronic medical record exchange and sharing. The privacy protection mechanism can be categorized into four types, namely anonymity, pseudonymity, unlinkability, and unobservability. In previous research in this area, mathematical conversions and cross reference tables have been utilized to conceal the confidential part of the electronic medical record to achieve privacy protection. However, it is harder to use these methods with respect to the unlinkability and unobservability mechanisms. Thus, this paper tries to improve on this aspect, and improves the unlinkability mechanism between the patient and the electronic medical record. Cloud computing is known for its fast computation capability and provides large storage space. Through cloud computing, the electronic medical record system in a hospital can be integrated, to facilitate the exchange and sharing of electronic medical records, and to provide smaller hospitals or clinics that have fewer resources with adequate electronic medical record storage space.
An assessment of the diagnosed prevalence of diseases in men 50 years of age or older. (2006)

The diseases identified in this study have the potential to cause significant clinical and economic implications when poorly treated or undertreated. Therefore, there is a need to institute early treatment for these conditions before they progress and require more extensive and costly interventions.
Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors (2002)

IHC in colorectal tumors for protein products hMLH1 and hMSH2 provides a rapid, cost-effective, sensitive (92.3%), and extremely specific (100%) method for screening for DNA mismatch repair defects. The predictive value of normal IHC for an MSS/MSI-L phenotype was 96.7%, and the predictive value of abnormal IHC was 100% for an MSI-H phenotype. Testing strategies must take into account acceptability of missing some cases of MSI-H tumors if only IHC is performed.
Does signal-attenuation on high-field T2-weighted MRI of the brain reflect regional cerebral iron deposition? Observations on the relationship between regional cerebral water proton T2 values and iron levels. (1989)

T2-weighted MRI shows attenuated signals from the basal ganglia, such signal attenuation being more evident at high magnetic field strengths of 1.5 tesla (T). The basal ganglia contain high levels of iron, and it has been suggested that these iron deposits lead to shortening of bulk water T2 protons via a mechanism involving diffusion of water through local magnetic field gradients generated by the iron. This mechanism generates a relaxation contribution that is proportional to the square of the applied static field B0, and if it is significant the relaxation rate 1/T2 should be strongly dependent on Bo. T2-weighted MRI would then provide a potential means of imaging regional cerebral iron levels at field strengths that are high enough for this mechanism to be important. The bulk water proton spin-spin relaxation times (T2) of samples from caudate nucleus, frontal cortex, and white matter, taken from fresh cerebral necropsy material of four subjects dying of non-neurological conditions, and one subject with Parkinson's disease have been measured. T2 values were compared with regional cerebral iron content. At high field strengths (2.35 T and 8.5 T) no significant variation in regional cerebral water proton T2 values was found; caudate, cortex and white matter had similar water proton spin-spin relaxation times in spite of the variation in their iron content. Increasing the field strength from 2.35 T to 8.5 T resulted in a generalised 50% decrease in mean regional cerebral T2 values, as opposed to the 13-fold decrease expected if T2 relaxation was dominated by a mechanism that is dependent on B02. It was thus not possible to provide evidence that iron deposition per se is responsible for the attenuated signal obtained from the basal ganglia in T2-weighted MRI.
Loop pipelining for high-throughput stream computation using self-timed rings (2006)

We present a technique for increasing the throughput of stream processing architectures by removing the bottlenecks caused by loop structures. We implement loops as self-timed pipelined rings that can operate on multiple data sets concurrently. Our contribution includes a transformation algorithm which takes as input a high-level program and gives as output the structure of an optimized pipeline ring. Our technique handles nested loops and is further enhanced by loop unrolling. Simulations run on benchmark examples show a 1.3 to 4.9x speedup without unrolling and a 2.6 to 9.7x speedup with twofold loop unrolling.
A mobile pen-based computing system for cellular telephone networks (2002)

We propose a mobile computing system based on pen computers and cellular telephones, and develop a prototype system. This system extends the personal office information environment to mobile use. To enable effective use of the conventional cellular telephone network, which has a low data communication speed, we propose new ideas to reduce the data communication traffic between the mobile station and the base station, such as distributed collaborative control, fixed business form manipulation using keywords communication, and a server and a gateway for the mobile station which filter and compress the information sent to the mobile station. The effective use of a pen-based human machine interface is also adopted. E-mail, facsimile, and transaction processing are targeted as the main applications of the system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Inorganic/organic mesostructure directed synthesis of wire/ribbon-like polypyrrole nanostructuresElectronic supplementary information (ESI) available: FT-IR spectra, powder XRD pattern and conductivities of as-made PPy nanostructures. See http://www.rsc.org/suppdata/cc/b4/b405255b/ (2004)

We report here a simple strategy for the synthesis of wire/ribbon-like polypyrrole nanostructures using lamellar inorganic/organic mesostructures as templates which were formed during polymerization between surfactant cations and oxidising anions and which were degraded automatically after polymerization.
Motility of the spirochete <i>leptospira</i> (1988)

Abstract Spirochetes are a group of bacteria with a unique ultrastructure and a fascinating swimming behavior. This article reviews the hydrodynamics of spirochete motility, and examines the motility of the spirochete Leptospira in detail. Models of Leptospira motility are discussed, and future experiments are proposed. The outermost structure of Leptospira is a membrane sheath, and within this sheath are a helically shaped cell cylinder and two periplasmic flagella. One periplasmic flagellum is attached subterminally at either end of the cell cylinder and extends partway down the length of the cell. In swimming cells, each end of the cell may assume either a spiral or a hook shape. Translational cells have the anterior end spiral shaped, and the posterior end hook shaped. In the model of Berg et al., the periplasmic flagella are believed to rotate between the sheath and the cell cylinder. Rotation of the anterior periplasmic flagellum causes the generation of a gyrating spiral‐shaped wave. This wave is believed sufficient to propel the cells forward in a low‐viscosity medium. The cell cylinder concomitantly rolls around the periplasmic flagella in the opposite direction—which allows the cell to literally screw through a gel‐like viscous medium without slippage. This model is presented, and it is contrasted to previous models of Leptospira motility.
Galactomannan from Soy Bean Hulls<sup>1,2</sup> (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGalactomannan from Soy Bean Hulls1,2Roy L. Whistler and Jouko SaarnioCite this: J. Am. Chem. Soc. 1957, 79, 22, 6055–6057Publication Date (Print):November 1, 1957Publication History Published online1 May 2002Published inissue 1 November 1957https://pubs.acs.org/doi/10.1021/ja01579a057https://doi.org/10.1021/ja01579a057research-articleACS PublicationsRequest reuse permissionsArticle Views160Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors (2014)

This is the most comprehensive genomic analysis of rhabdomyosarcoma to date. Despite a relatively low mutation rate, multiple genes were recurrently altered, including NRAS, KRAS, HRAS, FGFR4, PIK3CA, CTNNB1, FBXW7, and BCOR. In addition, a majority of rhabdomyosarcoma tumors alter the receptor tyrosine kinase/RAS/PIK3CA axis, providing an opportunity for genomics-guided intervention.
Intrathecal Baclofen Therapy (2006)

Practitioners from around the country who have extensive experience in intrathecal baclofen (ITB) therapy gathered in early 2004 to develop best-practice guidelines for ITB therapy. Discussion focused on the idea that ITB therapy is a program rather than a procedure. Key recommendations were made in areas including team coordination, patient selection and goals, patient education, patient screening, implant technique, long-term management, individualized dosing options, ongoing evaluation of patient response, appraisal of the integrity of the catheter and infusion system, and appropriate practice resources.
The Combinatorial BLAS: design, implementation, and applications (2011)

This paper presents a scalable high-performance software library to be used for graph analysis and data mining. Large combinatorial graphs appear in many applications of high-performance computing, including computational biology, informatics, analytics, web search, dynamical systems, and sparse matrix methods. Graph computations are difficult to parallelize using traditional approaches due to their irregular nature and low operational intensity. Many graph computations, however, contain sufficient coarse-grained parallelism for thousands of processors, which can be uncovered by using the right primitives. We describe the parallel Combinatorial BLAS, which consists of a small but powerful set of linear algebra primitives specifically targeting graph and data mining applications. We provide an extensible library interface and some guiding principles for future development. The library is evaluated using two important graph algorithms, in terms of both performance and ease-of-use. The scalability and raw performance of the example applications, using the Combinatorial BLAS, are unprecedented on distributed memory clusters.
THE EFFECT OF CARBONIC ANHYDRASE INHIBITION IN EXERCISING RATS, (1963)

A series of experiments has been performed to ascertain the effect of carbonic anhydrase inhibition on the ability of rats to exercise in room air and in an atmosphere of 6% O2. In separate experiments, it was first established that peak plasma concentrations of the inhibitor acetazolamide after intraperitoneal injection and peak PCO2 values in subcutaneous gas pouches occurred concomitantly at about 60 minutes. Rats trained to run on treadmills were able to run as long as 5 1/2 to 6 hours at 0.46 mile per hour in room air whether carbonic anhydrase was inhibited or not. When exercised in 6% O2, however, the animals in which carbonic anhydrase was inhibited ran 39% longer, on the average, than did control animals. The increase in ventilation, which is known to be induced during carbonic anhydrase inhibition, without consequent tissue hypocapnia and alkalosis probably accounted for the improved exercise performance of inhibited animals in a low-oxygen environment. (Author)
Design of systems for time delayed activated internal release of chemicals in concrete from porous fibers, aggregates of prills, to improve durability (1991)

Incorporation of chemicals into the internal matrix of cement or concrete, with later release occurring upon stimulation, alters the matrix parameters from those at the initial set. Permeability is reduced, for example, and therefore durability enhanced. The advantages of these designs would be the ability to reduce maintenance and repair costs in the initial building configuration and to delay the time of eventual repair. The components and the structure could take greater environmental abuse also. Permeability is significantly reduced by release of a polymer from wax-coated porous fibers upon heating to temperature of polymerization. Freeze/thaw damage is somewhat reduced by the timed release of linseed oil or antifreeze from porous aggregates due to the freezing action itself. These example designs using timed release mostly gave improved durability performance when compared to conventional treatments for durability or environmental distress. Concerns that significant strength reduction would occur due to heating or fiber loading were shown to be unfounded by our test results; indeed, heating and fiber inclusion increased strength. An adequate amount of wetting of the samples could be obtained with 2.75% volume of fibers; however, above a 2.75% volume of fibers, fibers do reduce the strength. Results were analyzed by the method of comparing results in the samples with factors varied to results in samples without variable factors, that is, by comparing to the controls. This research shows that timed internal release of chemicals into cement can be accomplished; it appears feasible and is potentially useful. Long-term tests need to be performed on such factors as chloride ion intrusion/ corrosion tests. Filled fiber, aggregate or prill manufacture, storage, and placement need to be researched and assessed for cost. Design of components using only targeted areas for release in the component and the use of time released fibers in reinforced cement laminates should be evaluated.
Copolymerizations initiated by mechano‐radicals on particle surfaces of poly(tetrafluoroethylene) (1978)

Abstract Mechanical fracture of solid poly(tetrafluoroethylene) (PTFE) produces main‐chain scissions of the polymer, and free radicals, called mechano‐radicals, are trapped on fresh surfaces generated by the fracture. These radical conversions were verified by ESR observation when several monomers—methylmethacrylate, vinylacetate, and ethylene—were brought into contact with these mechano‐radical, and the copolymerizations of PTFE with these monomers were demonstrated. It was found that a new surface property, wettability of water, was added to the solid PTFE by the copolymerization with vinyl acetate, although the bulk nature of PTFE was not changed.
Influence of Heat Treatment on Phases, Microstructures and Mechanical Properties of Laminated Fabric (SiC and Aluminosilicate)/ Mullite Matrix Composites (Part 2) (2005)

Influence of heat treatment at 1000-1500°C for 24 h on phases, microstructures and mechanical properties was studied for laminated SiC satin or aluminosilicate plain fabric/mullite matrix composites. Composites were produced by a polymer impregnation and pyrolysis method (PIP) using a mullite precursor. A mullite precursor solution of the mixtures of Si(OC2H5)4 and Al(NO3)3 was impregnated into the green layered fabric/mullite powder (filler) composite and was pyrolyzed at 500°C in air. This polymer impregnation and pyrolysis process was repeated 10 times. The SiC fabric (25-27 vol%)/mullite matrix composite with a relative density 72-75% showed weight loss after heat treatment in an Ar atmosphere (oxygen partial pressure ~0.75 Pa) at 1300-1500°C. This weight loss was due to the formation of volatile SiO gas resulting from the pyrolysis of mullite matrix (3Al2O3•2SiO2(s)→3Al2O3(s)+2SiO(g)+O2(g)) and active oxidation of the SiC fiber (SiC(s)+O2(g)→SiO(g)+CO(g)). The heat-treated SiC fabric/mullite matrix composites showed an elastic deformation in the initial stage of the stress-displacement curve, followed by pseudoductility. The strength (186 MPa) after the 1000°C heat treatment decreased to 17 MPa after the 1500°C heat treatment. The energy of fracture was 1-4 kJ/m2 in the heat treatment temperature range from 1000 to 1500°C.On the other hand, the aluminosilicate fabric (25-30 vol%)/mullite matrix composite with a relative density 71-73% showed no weight loss after heat treatment at 1000-1500°C in air. The porosity of the composite decreased with increasing heat treatment temperature because of the densification of the mullite matrix. This composite also showed pseudoductility after the heat treatment. The strength for the composite was slightly enhanced by increasing the heat treatment temperature.
Silicon–germanium spherical quantum dot infrared photodetectors prepared by the combination of bottom-up and top-down technologies (2004)

By combining a bottom-up, i.e., thermal evaporation method, and the top-down technologies, i.e., molecular beam epitaxy, the spherical SiGe quantum dot infrared photodetectors (QDIP) have been successfully fabricated for the first time. The thermal evaporation method was chosen to synthesize spherical SiGe nanoparticles. They are treated with methanol containing alumina powders in the ultrasonic bath to form a single SiGe dot layer with density about 1.6×1011 cm−2. The QDIP exhibits two response regions, i.e., 1–3.5 and 14–20 μm. The peak responsivity of QDIP is 5.4 mA/W at 2 μm and about 0.6 mA/W at 17 μm at a bias of 200 mV. This QDIP also exhibits photovoltaic response, a short circuit current exists at zero bias. This device is capable of operating up to 240 K with good performance.
Monocyte urokinase expression: modulation by interleukins (1993)

This study delineates the regulatory effect of interleukin-1 (IL-1) and interleukin-2 (IL-2) on monocyte plasminogen activator (PA) activity. Mononuclear phagocytes regulate net PA activity by modulating the expression of urokinase-type PA (uPA) and a specific plasminogen activator inhibitor, PAI-2. To understand the regulation of mononuclear phagocyte PA activity, it is important to compare the expression of uPA and PAI-2. In this study, we determined the relative abundance of secreted PA and PA inhibitor activity in human monocyte-conditioned medium after stimulation with human recombinant IL-1 or IL-2. In agreement with our previous description of tumor necrosis factor-alpha and interferon-gamma stimulation of mononuclear phagocytes, we found no detectable PA activity in conditioned medium. Both IL-1 and IL-2 had dose-dependent effects, significantly up-regulating PA inhibitor activity in monocyte-conditioned medium (up to 11-fold). To further investigate the mechanism underlying this effect, Northern blot analysis was done to measure steady-state mRNA for uPA and PAI-2. Consistent with the increase in secreted PA inhibitor activity, we found that both IL-1 and IL-2 significantly increased steady-state mRNA for PAI-2. In addition, however, both IL-1 and IL-2 increased steady-state mRNA for uPA. IL-1 appears to increase mRNA for uPA to a greater extent than does IL-2. We conclude that IL-1 and IL-2 modulate monocyte proteolytic activity by increasing expression of uPA and PAI-2 with a resultant predominance of PAI-2. We further conclude that cytokine-specific regulation of plasminogen activity is achieved partly by varying the proportionate expression of uPA and PAI-2.
An Overview of the EPIC Architecture for Cognition and Performance With Application to Human-Computer Interaction (1997)

Abstract EPIC (Executive Process-Interactive Control) is a cognitive architecture especially suited for modeling human multimodal and multiple-task performance. The EPIC architecture includes peripheral sensory-motor processors surrounding a production-rule cognitive processor and is being used to construct precise computational models for a variety of human-computer interaction situations. We briefly describe some of these models to demonstrate how EPIC clarifies basic properties of human performance and provides usefully precise accounts of performance speed.
Model simplification using vertex-clustering (1997)

This paper presents a practical technique to automaticallycompute approximations of polygonal representations of3D objects. It is based on a previously developed modelsimplification technique which applies vertex-clustering.Major advantages of the vertex-clustering technique are itslow computational cost and high data reduction rate, andthus suitable for use in interactive applications. This paperadvances the technique with careful consideration ofapproximation quality and smoothness in transitionsbetween different levels of simplification, whilemaintaining its efficiency and efb%iveness. Its majorcontributions include: accuracy in grading vertices forindication of their visual importance, robustness inclustering for better preservation of important fimtures andconsistencies between levels of simplification, thick-lineswith dynamic normals to maximize visual fidelity, andexploitation of object and image space relationship forlevels-of-simplificationdetermination.
The Action of Elementary Fluorine upon Organic Compounds. XVIII. A New Type of Reactor and the Mild Fluorination of Carbon Disulfide<sup>1</sup> (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Action of Elementary Fluorine upon Organic Compounds. XVIII. A New Type of Reactor and the Mild Fluorination of Carbon Disulfide1Edward A. Tyczkowski and Lucius A. BigelowCite this: J. Am. Chem. Soc. 1953, 75, 14, 3523–3526Publication Date (Print):July 1, 1953Publication History Published online1 May 2002Published inissue 1 July 1953https://pubs.acs.org/doi/10.1021/ja01110a063https://doi.org/10.1021/ja01110a063research-articleACS PublicationsRequest reuse permissionsArticle Views109Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts