gebhart/patrepeval huggingface dataset:
Meticulously detailed eye region model and its application to analysis of facial images (2006)

We propose a system that is capable of detailed analysis of eye region images in terms of the position of the iris, degree of eyelid opening, and the shape, complexity, and texture of the eyelids. The system uses a generative eye region model that parameterizes the fine structure and motion of an eye. The structure parameters represent structural individuality of the eye, including the size and color of the iris, the width, boldness, and complexity of the eyelids, the width of the bulge below the eye, and the width of the illumination reflection on the bulge. The motion parameters represent movement of the eye, including the up-down position of the upper and lower eyelids and the 2D position of the iris. The system first registers the eye model to the input in a particular frame and individualizes it by adjusting the structure parameters. The system then tracks motion of the eye by estimating the motion parameters across the entire image sequence. Combined with image stabilization to compensate for appearance changes due to head motion, the system achieves accurate registration and motion recovery of eyes.
Benzoylperoxide versus topical erythromycin in the treatment of acne vulgaris (1983)

In a double-blind clinical study in ninety-four subjects a 1.5% (w/v) erythromycin lotion was as effective as 5% (w/v) benzoyl peroxide gel in significantly reducing the number of small inflamed lesions and the overall acne severity. However, benzoyl peroxide also significantly reduced the number of non-inflamed lesions whereas erythromycin had no effect on these lesions. This study supports the view that, although topical erythromycin is of value in the treatment of mild or moderate acne vulgaris, long established, safe and effective remedies should not be replaced by topical antibiotics until more comparative studies and investigations on bacterial resistance have been completed.
Cell growth on immobilized cell growth factor. 9. Covalent immobilization of insulin, transferrin, and collagen to enhance growth of bovine endothelial cells (1993)

Bovine endothelial cells were cultivated on the surface of polyurethane membranes or tubes immobilized with insulin, transferrin, and/or collagen, and growth was measured. For the purpose of immobilization, amino groups were introduced on the membranes or tubes by glow-discharge treatment in the presence of ammonia gas. The proteins were coupled to the amino groups on the surfaces by using dimethyl suberimidate (DMS) or water-soluble carbodiimide (WSC). Growth of bovine endothelial cells was higher on immobilized insulin or transferrin using DMS than that using WSC. The cell growth was higher on immobilized insulin or transferrin than on free insulin or transferrin, respectively. Though immobilized collagen did not affect the cell growth, coimmobilization with insulin or transferrin brought about greater acceleration of cell growth. In addition, the immobilized collagen was indispensible to maintain the endothelial cells on the material surface for a long time. The endothelial cells grown in the polyurethane tubes, on which insulin and collagen are coimmobilized, kept a normal cobblestone-like appearance and maintained the ability to secrete prostacyclin for 9 months.
Gene expression profiling of esophageal cancer: Comparative analysis of Barrett's esophagus, adenocarcinoma, and squamous cell carcinoma (2007)

Esophageal cancer is a particularly aggressive tumor with poor prognosis, however, our current knowledge of the genes and pathways involved in tumorigenesis of the esophagus are limited. To obtain insight into the molecular processes underlying tumorigenesis of the esophagus, we have used cDNA microarrays to compare the gene expression profiles of 128 tissue samples representing the major histological subtypes of esophageal cancer (squamous cell carcinoma and adenocarcinoma (ADC)) as well as Barrett's esophagus (BE), the precursor lesion to ADC, and normal esophageal epithelium. Linear discriminant analysis and unsupervised hierarchical clustering show the separation of samples into 4 distinct groups consistent with their histological subtype. Differentially expressed genes were identified between each of the tissue types. Comparison of gene ontologies and gene expression profiles identified gene profiles specific to esophageal cancer, as well as BE. "Esophageal cancer clusters," representing proliferation, immune response, and extracellular matrix genes were identified, as well as digestion, hydrolase, and transcription factor clusters specific to the columnar phenotype observed during BE and esophageal ADC. These clusters provide valuable insight into the molecular and functional differences between normal esophageal epithelium, BE, and the 2 histologically distinct forms of esophageal cancers. Our thorough, unbiased analysis provides a rich source of data for further studies into the molecular basis of tumorigenesis of the esophagus, as well as identification of potential biomarkers for early detection of progression.
Canary Replica Feedback for Near-DRV Standby V<inf>DD</inf> Scaling in a 90nm SRAM (2007)

Canary bitcells act as online monitors in a feedback architecture to sense the proximity to the data retention voltage (DRV) for core SRAM bitcells during standby voltage scaling. This approach implements aggressive standby V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> scaling by tracking PVT variations and gives the flexibility to tradeoff between the safety of data and decreased leakage power. A 90 nm 128 Kb SRAM test chip confirms that the canary cells track changes in temperature and V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> and that they provide a reliable mechanism for protecting core cells in a closed loop V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> scaling system. Power savings improve by up to 30times compared with the conventional guard-banding approach.
Evanescent Wave Coupling Using Different Subwavelength Gratings for a MEMS Accelerometer (2011)

A novel technique of coupling near-field evanescent waves by means of variable period subwavelength gratings (1.2 ìm and 1.0 ìm), using a 1.55 ìm infrared semiconductor laser is presented for the use of an optical MEMS accelerometer. The subwavelength gratings were fabricated on both glass and silicon substrates respectively.\nOptical simulation of the subwavelength gratings was carried out to obtain the maximum coupling efficiency of the two subwavelength gratings; the grating thickness, grating width, and the grating separation were optimized. This was performed for both silicon and glass substrates.\nThe simulations were used to determine the total system noise, including the noise generated from the germanium photodiode, sensitivity, and displacement detection resolution of the coupled subwavelength grating MEMS accelerometer. The coupled gratings were utilized as optical readout accelerometers.\nThe spring/proof mass silicon accelerometer was fabricated using a four mask process, in which the structure was completed using two deep reactive ion etching (DRIE) processes. The designed serpentine spring styles determine the sensitivity of the accelerometer; when the springs are made longer or shorter, thicker or thinner, this directly attributes to the sensitivity of the device.\nTo test function of the example of the devices, the accelerometer is placed on a platform, which permits displacement normal to the plane of the grating. The 1.550 ìm infrared laser is incident on the coupled subwavelength grating accelerometer device and the output intensity is measured using a geranium photodiode. As the platform is displaced, the grating separation between the two gratings changes and causes the output intensity to change. Using the coupled subwavelength grating simulations as a reference to the output intensity change with respect to gap, the mechanical and coupling sensitivity properties of as it relates to acceleration is presented.
Conditional biallelic <i>Nf2</i> mutation in the mouse promotes manifestations of human neurofibromatosis type 2 (2000)

Hemizygosity for the NF2 gene in humans causes a syndromic susceptibility to schwannoma development. However, Nf2 hemizygous mice do not develop schwannomas but mainly osteosarcomas. In the tumors of both species, the second Nf2 allele is inactivated. We report that conditional homozygous Nf2 knockout mice with Cre-mediated excision of Nf2 exon 2 in Schwann cells showed characteristics of neurofibromatosis type 2. These included schwannomas, Schwann cell hyperplasia, cataract, and osseous metaplasia. Thus, the tumor suppressor function of Nf2, here revealed in murine Schwann cells, was concealed in hemizygous Nf2 mice because of insufficient rate of second allele inactivation in this cell compartment. The finding of this conserved function documents the relevance of the present approach to model the human disease.
Quantum Dot−Carrier Peptide Conjugates Suitable for Imaging and Delivery Applications (2008)

We developed multifunctional fluorescent nanoparticles suitable for the nonviral delivery of negatively charged molecules like RNA. Therefore, we incorporated the recently developed branched hCT-derived carrier peptide hCT(18-32)-k7 on the surface of luminescent quantum dots (QDs). Besides detailed characterization of our QD-peptide conjugates concerning stability, toxicity, and uptake mechanism. we used them for efficient RNA delivery into different cell lines. The results of our studies indicate the involvement of more than one endocytotic uptake pathway in the internalization process. Furthermore, we could show that the QD-peptide bioconjugates exhibit no effect on cell viability and possess high stability inside living cells. The efficacy of our newly designed constructs for oligonucleotide drug delivery is highlighted by the successful intracellular transport of Cy-3 labeled RNA. Moreover, by using the chemotherapeutic chloroquine the efficient release of the assemblies out of endosomes was demonstrated. These results prove that our multifunctional platforms are versatile tools for diagnostic and therapeutic imaging purposes applicable for biologically active siRNA or aptamer sequences.
Simulation and performance analysis of CCM Zeta converter with PID controller (2015)

DC-DC conversion is the chief stem of Power Electronics and is progressing rapidly. Many new topologies are still created every year. The Zeta converter is another converter topology to provide a regulated output voltage from an input voltage that varies above and below the output voltage. The benefits of the Zeta converter over the SEPIC converter include lower output-voltage ripple and easier compensation. The non-pulsating output current of the Zeta converter allows for the use of small output capacitors for satisfying the load voltage ripple requirement. The objective of this paper is to design and implement the CCM mode operation of non-isolated Zeta converter. The design formulas for the continuous conduction mode (CCM) are given. This paper deals with design and steady state analysis of closed loop non-isolated Zeta converter using PID control technique. The simulations have been performed by using MATLAB/Simulink. Through simulation it is confirmed that a PID compensation method improves the output response of the system.
Question identification on twitter (2011)

In this paper, we investigate the novel problem of automatic question identification in the microblog environment. It contains two steps: detecting tweets that contain questions (we call them "interrogative tweets") and extracting the tweets which really seek information or ask for help (so called "qweets") from interrogative tweets. To detect interrogative tweets, both traditional rule-based approach and state-of-the-art learning-based method are employed. To extract qweets, context features like short urls and Tweet-specific features like Retweets are elaborately selected for classification. We conduct an empirical study with sampled one hour's English tweets and report our experimental results for question identification on Twitter.
On self-routing in Benes and shuffle-exchange networks (1991)

The authors present self-routing algorithms for realizing the class of linear permutations in various multistage networks such as Benes and 2n-stage shuffle-exchange. Linear permutations are useful in providing fast access of data arrays. In the first half of the network, switches are set by comparing the destination tags at their inputs, and, in the second half, switches are set using the Omega self-routing algorithm. It is shown that the comparison operations can be implemented in bit-serial networks without loss of time. In contrast, with the well-known Benes network self-routing algorithm of D. Nassimi and S. Sahni (1981), switches are set by giving priority to the destination tag at the upper input to them. The algorithms presented are useful in providing fast access of various data patterns using interconnection networks cheaper than crossbars.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The design and analysis of a double swivel toggle release mechanism for the Orbiter stabilized payload deployment system (1989)

The NASA Stabilized Payload Deployment System (SPDS) is discussed. The lightweight and heavy-duty system rolls payloads over the orbiter's side rather than ejecting them upward. The system will enhance the orbiter capability of carrying larger and heavier payloads. The design, function, and analysis of a new three-pin double swivel toggle release mechanism which is crucial to the successful deployment of the SPDS are described.
Autonomic self-healing systems in a cross-product IT environment (2004)

This paper presents the architecture and implementation of a prototype system developed to investigate fixing real-world problems with self-healing systems. Case studies performed to evaluate the efficacy of this approach are described along with the issues encountered and lessons learned.
Bioenergetic analysis of mixotrophic growth in <i>Chlorella vulgaris</i> and <i>Scenedesmus acutus</i> (1981)

Abstract The specific growth rate of Chlorella vulgaris in the presence of glucose (mixotroph) was always larger than that in autotroph when the light intensity was less than 10 klux. However, Scenedesmus acutus behaved differently, i.e., when the light intensity was more than 6 klux, the specific growth rate in mixotroph became smaller than that in autotroph. Cellular contents of chlorophyll a and b in Scenedesmus acutus that deteriorated more markedly in mixotroph than those of Chlorella vulgaris could account for these different growth behaviors. In other words, mechanisms relevant to the photosynthesis and the oxidative phosphorylation of glucose seem to function independently with respect to Chlorella Vulugaris .
The healing and tensile strength of the gastroplasty staple line. An experimental study. (1984)

Inverted and everted staple lines, with and without division of the anterior gastric wall, were performed in 15 mongrel dogs to simulate reduction gastroplasty staple line. There were no significant differences in tensile strength and healing between staple lines at different postoperative periods. The tensile strength of the inverted staple line seemed to be stronger due to breakage of the adjacent gastric tissue. However, the tensile strength of the everted stapling without division of the gastric wall, which is used clinically, was almost equal to that of normal gastric tissue. In addition, there was satisfactory healing 4 weeks postoperatively in the everted stapling without dividing the gastric wall. These results suggest that the everted staple line without division of stomach is not inherently weaker to any significant extent than if the gastric wall was divided or inverted. The reported failure rate of this procedure may be due to other factors.
Stereospecific Pd-Catalyzed Cross-Coupling Reactions of Secondary Alkylboron Nucleophiles and Aryl Chlorides (2014)

We report the development of a Pd-catalyzed process for the stereospecific cross-coupling of unactivated secondary alkylboron nucleophiles and aryl chlorides. This process tolerates the use of secondary alkylboronic acids and secondary alkyltrifluoroborates and occurs without significant isomerization of the alkyl nucelophile. Optically active secondary alkyltrifluoroborate reagents undergo cross-coupling reactions with stereospecific inversion of configuration using this method.
Backscattering of electromagnetic missile by a perfectly conducting elliptical cylinder (1991)

Recently the backscattering of an electromagnetic (EM) missile with an energy decreasing as r−ε by a perfectly conducting plate has been studied and the analysis shows that the energy backscattered varies as r−ε with the same exponent as the incident EM missile. Scattering of an EM missile by other shapes is left as an open question. In this paper we study the backscattering of an EM missile with energy decreasing as r−ε by a perfectly conducting elliptical cylinder. It has been shown that the rate of the energy decay for the backscattered field far from the cylinder is proportional to r−(1+ε), which is faster than r−ε for plate scattering but still slower than the ordinary energy decay r−2 for a two-dimensional backscattered field.
Disulfide Bond Requirements for Active Wnt Ligands (2014)

Secreted Wnt lipoproteins are cysteine-rich and lipid-modified morphogens that bind to the Frizzled (FZD) receptor and LDL receptor-related protein 6 (LRP6). Wnt engages FZD through protruding thumb and index finger domains, which are each assembled from paired β strands secured by disulfide bonds and grasp two sides of the FZD ectodomain. The importance of Wnt disulfide bonds has been assumed but uncharacterized. We systematically analyzed cysteines and associated disulfide bonds in the prototypic Wnt3a. Our data show that mutation of any individual cysteine of Wnt3a results in covalent Wnt oligomers through ectopic intermolecular disulfide bond formation and diminishes/abolishes Wnt signaling. Although individual cysteine mutations in the amino part of the saposin-like domain and in the base of the index finger are better tolerated and permit residual Wnt3a secretion/activity, those in the amino terminus, the thumb, and at the tip of the index finger are incompatible with secretion and/or activity. A few select double cysteine mutants based on the disulfide bond pattern restore Wnt secretion/activity. Further, a double cysteine mutation at the index finger tip results in a Wnt3a with normal secretion but minimal FZD binding and dominant negative properties. Our results experimentally validate predictions from the Wnt crystal structure and highlight critical but different roles of the saposin-like and cytokine-like domains, including the thumb and the index finger in Wnt folding/secretion and FZD binding. Finally, we modified existing expression vectors for 19 epitope-tagged human WNT proteins by removal of a tag-supplied ectopic cysteine, thereby generating tagged WNT ligands active in canonical and non-canonical signaling.
Distributed pseudo-random bit generators---a new way to speed-up shared coin tossing (1996)

Article Distributed pseudo-random bit generators—a new way to speed-up shared coin tossing Share on Authors: Mihir Bellare Department of Computer Science & Engineering, Mail Code 0114, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA Department of Computer Science & Engineering, Mail Code 0114, University of California at San Diego, 9500 Gilman Drive, La Jolla, CAView Profile , Juan A. Garay CWI, Kruislaan 413, 1098 SJ Amsterdam, The Netherlands, and IBM T.J. Watson Research Center, PO Box 704, Yorktown Heights, New York CWI, Kruislaan 413, 1098 SJ Amsterdam, The Netherlands, and IBM T.J. Watson Research Center, PO Box 704, Yorktown Heights, New YorkView Profile , Tal Rabin MIT Laboratory for Computer Science, 545 Technology Square, Cambridge, MA MIT Laboratory for Computer Science, 545 Technology Square, Cambridge, MAView Profile Authors Info & Claims PODC '96: Proceedings of the fifteenth annual ACM symposium on Principles of distributed computingMay 1996 Pages 191–200https://doi.org/10.1145/248052.248090Online:01 May 1996Publication History 10citation232DownloadsMetricsTotal Citations10Total Downloads232Last 12 Months9Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Performance evaluation of IEEE 802.11 (2002)

This paper analyzes the performance of IEEE 802.11 MAC protocol under a disaster scenario. The performance is measured in terms of the recovery time and the throughput of the protocol when a network disaster occurs. To make the problem amenable to analysis, some approximations are used, and a new technique to collapse a very large state space is introduced. The analytical results are found to agree with simulations.
Pilot-Aided Carrier Recovery in the Presence of Phase Noise (2011)

The paper deals with carrier recovery based on pilot symbols in single-carrier systems. The system model considered in the paper includes the channel additive white noise and the phase noise that affects the local oscillators used for up/down-conversion. Wiener's method is used to determine the optimal filter in estimation of phase noise assuming that a sequence of equally spaced pilot symbols is available. Our analysis allows to capture the cyclostationary performance of the estimate, a phenomenon that is not considered in the previous literature. In the paper, closed-form formulas for the transfer function of the optimal filter and for the mean-square phase error are derived for the case where the phase noise is modelled as random phase walk. For this case, a suboptimal filter is proposed. Numerical results are presented to substantiate the analysis.
On aligning curves (2003)

We present a novel approach to finding a correspondence (alignment) between two curves. The correspondence is based on a notion of an alignment curve which treats both curves symmetrically. We then define a similarity metric based on the alignment curve using two intrinsic properties of the curve, namely, length and curvature. The optimal correspondence is found by an efficient dynamic-programming method both for aligning pairs of curve segments and pairs of closed curves, and is effective in the presence of a variety of transformations of the curve. Finally, the correspondence is shown in application to handwritten character recognition, prototype formation, and object recognition, and is potentially useful in other applications such as registration and tracking.
Stroboscopic observation of cylindrical domain propagation in a T-bar structure (1970)

A technique of stroboscopic observation has been applied to the examination of the dynamic behavior of cylindrical magnetic domains, in a single crystal platelet of Sm 0.55 Tb 0.45 FeO 3 , propagating around a closed path Permalloy film T-bar structured overlay. Domain propagation is achieved by means of the time-varying magnetic pole configuration induced by a rotating magnetic field in the plane of the Permalloy film. Semiquantitative measurements under conditions of continuous propagation show instantaneous wall velocities varying from almost zero to greater than six times the time-averaged domain velocity. The speed of propagation in this T-bar structure is limited by the design of the comer where domains become trapped. The stroboscopic technique used here should find important application in the dynamic evaluation of designs for domain-propagation structures.