gebhart/patrepeval huggingface dataset:
Synthesis of Conductive Polypyrrole/Polyurethane Foams via a Supercritical Fluid Process (1997)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSynthesis of Conductive Polypyrrole/Polyurethane Foams via a Supercritical Fluid ProcessYueping Fu, Daniel R. Palo, Can Erkey, and R. A. WeissView Author Information Department of Chemical Engineering, University of Connecticut, Storrs, Connecticut 06269Cite this: Macromolecules 1997, 30, 24, 7611–7613Publication Date (Web):December 1, 1997Publication History Received17 July 1997Revised26 September 1997Published online1 December 1997Published inissue 1 December 1997https://pubs.acs.org/doi/10.1021/ma9710747https://doi.org/10.1021/ma9710747brief-reportACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views660Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Foams,Organic polymers,Polymerization,Polymers,Pyrroles Get e-Alerts
Biologic Enhancement of Spinal Fusion (1995)

The efficacy of bone growth factors for lumbar fusion remains to be definitively established in humans.
Development of network management system for network services provider (2011)

Network management system (NMS) is important both in ensuring the correct operation of network devices and in maintaining the services that run on them. However, the relentless growth of DSL's users, meaning that IP traffic volumes nearly double every two years, renders real-time monitoring and analysis of every customer's service parameter is a very challenging problem. The most important problem is the bottleneck in centralized NMS which most of services provider use as SNMP-based system. This paper presents a new model which will be able to ease the problem from bandwidth consumption of SNMP-based by two main methods. Firstly, to ease the problem from bandwidth consumption of SNMP-based, this model will use the probabilistic data structure to decrease the number of packets of monitoring network device's parameter. Secondly, to ease the problem from the relentless growth of the number of the network's devices, this model is designed to support distributed network devices' operations in a distributed NMS fashion. Meaning that, the number of NMS's devices can be increased with the number of network's devices if it is necessary. By using both of two methods, customer expectations with bandwidth requirements and reliability requirements can be improved with this model.
Purification of histidine‐tagged single‐chain Fv‐antibody fragments by metal chelate affinity precipitation using thermoresponsive copolymers (2003)

Metal chelate affinity precipitation (MCAP) has been successfully developed as a simple purification process for proteins that have affinity for metal ions. The present lack of widespread applications for this technique as compared to immobilized metal affinity chromatography (IMAC) may be related to the scarcity of well-characterized metal affinity macroligands (AML) and their applications to the number of different purification systems. In the present work we describe a detailed study of a new purification system using metal-loaded thermoresponsive copolymers as AML. The copolymers of vinylimidazole (VI) with N-isopropylacrylamide (NIPAM) were synthesized by radical polymerization with imidazole contents of 15 and 24 mol%. When loaded with Cu(II) and Ni(II) ions the copolymers selectively precipitated extracellularly expressed histidine-tagged single-chain Fv-antibody fragments (His(6)-scFv fragments) from the fermentation broth free from E. coli cells. Precipitation was induced by salt at mild temperatures and the bound antibody fragments were recovered by dissolving the protein-polymer complex in EDTA buffer and subsequent reprecipitation of the polymer. His(6)-scFv fragments were purified with yields of 91 and 80% and purification folds of 16 and 21 when Cu(II) and Ni(II) copolymers were used, respectively. The protein precipitation capacity of the Ni(II) copolymer showed a dependence on the VI concentration in the copolymer. The SDS-PAGE pattern showed significant purification of the antibody fragments.
Synthesis of 2′,3′-Dideoxy-3′-nitro-2′,3′-didehydrothymidine. Its Use as a General Intermediate for the Preparation of Various 2′,3′-Substituted Nucleosides (1993)

Abstract The first synthesis of 1-(2,3-dideoxy-3-nitro-β-D-glycero-pent-2-enofuranosyl)thymine (7), is reported starting directly from l-β-D-xylofuranosyl)thymine (1). We also report a stereospecific conversion of (6) to 3′-nitro-2′,3′-dideoxythymidine (9). Detailed NMR studies have shown that the solution conformation of 3′-nitro-2′,3′-dideoxythymidine (9) is very similar to 3′-fluoro-2′,3′-dideoxythymidine but the former is almost 100 fold less active than the later against HIV reverse transcriptase. Subsequently, the synthetic utilities of 1-(2,3-dideoxy-3-nitro-β-D-glycero-pent-2-enofuranosyl) thymine, (6) and (7), in the preparation of various 2′- and 3′-modified nucleosides have been established through Michael addition reactions with various oxygen, nitrogen and carbon nucleophiles.
Rapid detection of rare geospatial events (2011)

The paper presents theory, algorithms, measurements of experiments, and simulations for detecting rare geospatial events by analyzing streams of data from large numbers of heterogeneous sensors. The class of applications are rare events - such as events that occur at most once a month - and that have very high costs for tardy detection and for false positives. The theory is applied to an application that warns about the onset of shaking from earthquakes based on real-time data gathered from different types of sensors with varying sensitivities located at different points in a region. We present algorithms for detecting events in Cloud computing servers by exploiting the scalability of Cloud computers while working within the limits of state synchronization across different servers in the Cloud. Ordinary citizens manage sensors in the form of mobile phones and tablets as well as special-purpose stationary sensors; thus the geospatial distribution of sensors depends on population densities. The distribution of the locations of events may, however, be different from population distributions. We analyze the impact of population distributions (and hence sensor distributions as well) on the efficacy of event detection. Data from sensor measurements and from simulations of earthquakes validate the theory.
Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells (2003)

Effective natural killer (NK) cell recognition of murine cytomegalovirus (MCMV)-infected cells depends on binding of the Ly49H NK cell activation receptor to the m157 viral glycoprotein. Here we addressed the immunological consequences of variation in m157 sequence and function. We found that most strains of MCMV possess forms of m157 that evade Ly49H-dependent NK cell activation. Importantly, repeated passage of MCMV through resistant Ly49H+ mice resulted in the rapid emergence of m157 mutants that elude Ly49H-dependent NK cell responses. These data provide the first molecular evidence that NK cells can exert sufficient immunological pressure on a DNA virus, such that it undergoes rapid and specific mutation in an NK cell ligand enabling it to evade efficient NK cell surveillance.
Mechanically Induced Superfilling of Low-Aspect-Ratio Cavities in an Electrochemical Mechanical Deposition Process (2004)

Electrochemical mechanical deposition (ECMD) is a new technique that has the ability to deposit planar copper films on nonplanar substrate surfaces. This technique involves electrochemical deposition and simultaneous sweeping of the substrate surface with a planarization pad. In this study we show that planarization of low-aspect-ratio features on a wafer surface by ECMD is due to a newly identified "mechanically induced superfilling" phenomenon. Sweeping of the top surface of the wafer at preset intervals establishes a transient differential in the surface coverage of organic additives at the top surface and the cavity regions, preferentially increasing the current flow into the cavities. Planarization decreases as the time interval between sweeps increases. Increase in the deposition rate of copper into the low-aspect-ratio features results in an associated decrease of deposition onto the top surface under galvanostatic conditions. A model that invokes surface coverage transients of accelerator species is offered to explain the experimental results. © 2004 The Electrochemical Society. All rights reserved.
Surface Chemistry of Cu in the Presence of CO<sub>2</sub> and H<sub>2</sub>O (2008)

The chemical nature of copper and copper oxide (Cu 2O) surfaces in the presence of CO 2 and H 2O at room temperature was investigated using ambient pressure X-ray photoelectron spectroscopy. The studies reveal that in the presence of 0.1 torr CO 2 several species form on the initially clean Cu, including carbonate CO 3 (2) (-), CO 2 (delta-) and C (0), while no modifications occur on an oxidized surface. The addition of 0.1 ML Zn to the Cu results in the complete conversion of CO 2 (delta-) to carbonate. In a mixture of 0.1 torr H 2O and 0.1 torr CO 2, new species are formed, including hydroxyl, formate and methoxy, with H 2O providing the hydrogen needed for the formation of hydrogenated species.
Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing (1990)

Ras gene is one of the oncogenes most commonly detected in human cancers and consists of three families (H-ras, K-ras, N-ras) that are converted to active oncogenes by point mutations occurring in codon 12, 13, or 61. The authors analyzed mutations of these codons in 12 extrahepatic bile duct carcinomas, nine gallbladder carcinomas, and 20 pancreatic tumors (18 pancreatic adenocarcinomas and two islet cell tumors) by a method to directly sequence nucleotides, using polymerase chain reaction and a direct sequencing method. Point mutations at K-ras codon 12 were found in all of 18 pancreatic adenocarcinomas and in one bile duct carcinoma, but there were no mutations in the remaining 11 bile duct carcinomas, in all of 9 gallbladder carcinomas, or in two islet cell tumors. A very high incidence of ras gene mutations may be used clinically for the diagnosis of debatable cases of pancreatic adenocarcinoma.
AWOL: an adaptive write optimizations layer (2008)

Operating system memory managers fail to consider the population of read versus write pages in the buffer pool or outstanding I/O requests when writing dirty pages to disk or network file systems. This leads to bursty I/O patterns, which stall processes reading data and reduce the efficiency of storage. We address these limitations by adaptively allocating memory between write buffering and read caching and by writing dirty pages to disk opportunistically before the operating system submits them for write-back. We implement and evaluate our methods within the Linux® operating system and show performance gains of more than 30% for mixed read/write workloads.
Ferroelectric thin film and broadband satellite systems (2001)

There are several microwave applications where tunable ferroelectric devices could play a key role in improving system performance, or they could provide the key technology that enables a system to be deployed. This article focuses on the Ka-band phased array antennas, but tunable filters, oscillators, and switches could also utilize these materials.
A Linux based software router supporting QoS, policy based control and mobility (2004)

In order to accommodate the new generation of Internet applications, routers need to be designed to support QoS, policy based management, and mobility. This paper presents architecture for the control plane of a software router that integrates signaling protocols and control mechanisms for QoS, policy based management, and mobile IP. The architecture has the flexibility of using the policy control to dynamically configure routers to act as nodes in an IntServ of DiffServ domain. Within each domain the routers can be configured to control their resource usage or to implement service level agreements. Implementation of a software router based on Linux and the experimental results are presented. The results show that with software routers this architecture can be used to meet the end-to-end QoS performance for most Internet applications.
Carbon Materials as Supports for Fuel Cell Electrocatalysts (2008)

International audience
PDMS‐Based Elastomer Tuned Soft, Stretchable, and Sticky for Epidermal Electronics (2016)

A highly soft, stretchable, and sticky polydimethylsiloxane-based elastomer is achieved by adding small fractions of an amine-based polymer. The modified elastomer is tuned with a simple mixing step and shows good processability for microstructure fabrication. The modified elastomer shows excellent compatibility with an epidermal strain sensor on human skin.
Model-based scattering bars implementation for 65nm and 45nm nodes using IML technology (2005)

Scattering Bars (SB) OPC, together with optimized illumination, is no doubt one of the critical enablers for low k<sub>1</sub> lithography manufacturing. The manufacturing implementation of SB so far has been mainly based on rule-based approach. While this has been working well, a more effective model-based approach is much more desired lithographically for manufacturing at 65nm and 45nm nodes. This is necessary to ensure sufficient process margin using hyper NA for patterning random IC design. In our model-based SB (M-SB) OPC implementation, we have based on the patented IML Technology from ASML MaskTools. In this report, we use both dark field contact hole and clear field poly gate mask to demonstrate this implementation methodology. It is also quite applicable for dark field trench masks, such as local interconnect mask with damascene metal. For our full-chip implementation flow, the first step is to determine the critical design area and then to proceed with NA and illumination optimization. We show that, using LithoCruiser, we are able to select the best NA in combination with optimum illumination via a Diffraction Optical Element (DOE). The decision to use a custom DOE or one from the available DOE library from ASML can be made based on predicted process performance and cost effectiveness. With optimized illumination, it is now possible to construct an interference map for the full-chip mask pattern. Utilizing the interference map, M-SB OPC is generated. Next, model OPC can be applied with the presence of M-SB for the entire chip. It is important to note here, that from our experience, the model OPC must be calibrated with the presence of SB in order to achieve the desired accuracy. We report the full-chip processing benchmark using MaskWeaver to apply both M-SB and model OPC. For actual patterning performance, we have verified the full chip OPC treatment using SLiC, a DFM tool from Cadence. This implementation methodology can be applied to binary chrome mask, attenuated PSM, and CPL.
Bringing home the trash: do differences in foraging lead to increased plastic ingestion in Laysan Albatrosses? (2009)

When searching for prey, animals should maximize energetic gain, while minimizing energy expenditure by altering their movements relative to prey availability. However, with increasing amounts of marine debris, what once may have been ‘optimal’ foraging strategies for top marine predators, are leading to sub-optimal diets comprised in large part of plastic. Indeed, the highly vagile Laysan albatross (Phoebastria immutabilis) which forages throughout the North Pacific, are well known for their tendency to ingest plastic. Here we examine whether Laysan albatrosses nesting on Kure Atoll and Oahu Island, 2,150 km apart, experience different levels of plastic ingestion. Twenty two geolocators were deployed on breeding adults for up to two years. Regurgitated boluses of undigestable material were also collected from chicks at each site to compare the amount of plastic vs. natural foods. Chicks from Kure Atoll were fed almost ten times the amount of plastic compared to chicks from Oahu despite boluses from both colonies having similar amounts of natural food. Tracking data indicated that adults from either colony did not have core overlapping distributions during the early half of the breeding period and that adults from Kure had a greater overlap with the putative range of the Western Garbage Patch corroborating our observation of higher plastic loads at this colony. At-sea distributions also varied throughout the year suggesting that Laysan albatrosses either adjusted their foraging behavior according to constraints on time away from the nest or to variation in resources. However, in the non-breeding season, distributional overlap was greater indicating that the energy required to reach the foraging grounds was less important than the total energy available. These results demonstrate how a marine predator that is not dispersal limited alters its foraging strategy throughout the reproductive cycle to maximize energetic gain and how this has led to differences in plastic ingestion.
Flasks, fibres and flanks – pre-clinical tumour models for predicting clinical antitumour activity (2001)

in xenograft models, which itself can to some extent be predicted by activity in the hollow fibre model and in turn in in vitro cell lines, is of value. Whether this remains the case for the new generation of cancer target-specific drugs remains to be seen and a new experiment, potentially the last, is just beginning.
ChemInform Abstract: A NEW MODIFICATION OF THE POMERANZ‐FRITSCH ISOQUINOLINE SYNTHESIS (1975)

Abstract Die Tosylate (IIb) von durch Reduktion Schiffscher Basen aus substituierten Benzaldehyden und Aminoacetaldehyd‐dimethylacetal, wie z.B. (I), erhältlichen Aminen, wie (IIa), lassen sich durch längeres Erhitzen in Dioxan in Gegenwart von HCl zu Isochinolinen, wie (IV), cyclisieren.
Modeling of a PSA-TSA Process for Separation of CH<sub>4</sub>from C<sub>2</sub>Products of OCM Reaction (2012)

Computational modeling of C2H6–C2H4 adsorption separation from CH4 onto CaX zeolite is discussed. Dynamic adsorption is studied to derive mass transfer parameters of the components. A two-bed and four-step PSA-TSA is introduced and sensitivity analysis is performed to approach to the higher products’ purity and recovery. CH4-countercurrent pressurization, as the preferred method and optimum purge/ feed of 0.49 are determined for the light (CH4) and heavy products (C2s) recovery of 84% and 96%, with a purity of 95% and 72%, respectively. The effect of desorption temperature and heat transfer coefficient are studied to determine the temperature variation effect on the process performance.
Surfactant protein D regulates chemotaxis and degranulation of human eosinophils (2006)

The collectin surfactant protein D (SP-D) is an important component of the pulmonary innate host defence. Up to now, little is known about the regulation of eosinophil function by SP-D. Various murine models of pulmonary hypersensitivity suggest that SP-D may be a potent anti-allergic protein. We investigated the modulation of eosinophil chemotaxis and degranulation by human SP-D. SP-D markedly inhibited the chemotaxis of eosinophils triggered by eotaxin, a major tissue-derived CC-chemokine, as shown in a modified Boyden chamber assay. In addition, degranulation of ECP in response to Ca2+ ionophore, immobilized IgG and serum from allergic patients was inhibited by SP-D. In a fixed-cell enzyme linked immunosorbent assay and in flow cytometry, SP-D bound to eosinophils. This binding was saturable and was inhibited by the addition of maltose and ethylenediaminetetraacetic acid, suggesting the involvement of the carbohydrate recognition domain of SP-D. In addition, flow cytometry showed significant interaction of SP-D with CD32 (FcgammaII receptor) on eosinophils, which might explain the inhibitory effect of SP-D on the IgG and serum-triggered eosinophil cationic protein degranulation of eosinophils. Our data further support the concept of an anti-inflammatory function of SP-D in the lung of patients with allergic diseases.
Adaptive Learning with the LS-Plan System: A Field Evaluation (2009)

LS-Plan is a framework for personalization and adaptation in e-learning. In such framework an Adaptation Engine plays a main role, managing the generation of personalized courses from suitable repositories of learning nodes and ensuring the maintenance of such courses, for continuous adaptation of the learning material proposed to the learner. Adaptation is meant, in this case, with respect to the knowledge possessed by the learner and her learning styles, both evaluated prior to the course and maintained while attending the course. Knowledge and Learning styles are the components of the student model managed by the framework. Both the static, precourse, and dynamic, in-course, generation of personalized learning paths are managed through an adaptation algorithm and performed by a planner, based on Linear Temporal Logic. A first Learning Objects Sequence is produced based on the initial learner's Cognitive State and Learning Styles, as assessed through prenavigation tests. During the student's navigation, and on the basis of learning assessments, the adaptation algorithm can output a new Learning Objects Sequence to respond to changes in the student model. We report here on an extensive experimental evaluation, performed by integrating LS-Plan in an educational hypermedia, the LecompS web application, and using it to produce and deliver several personalized courses in an educational environment dedicated to Italian Neorealist Cinema. The evaluation is performed by mainly following two standard procedures: the As a Whole and the Layered approaches. The results are encouraging both for the system on the whole and for the adaptive components.