gebhart/patrepeval huggingface dataset:
Multiple myeloma and the translocation t(11;14)(q13;q32): a report on 13 cases (1998)

Complex cytogenetic abnormalities have been described in patients with multiple myeloma (MM). To better understand the significance of the most frequent translocation observed in MM, we studied the clinical characteristics of patients with MM and the t(11;14)(q13;q32) abnormality. A search of the cytogenetic database at the Mayo Clinic identified patients with MM and t(11;14)(q13;q32). The medical records were reviewed for the clinical characteristics of these patients. We identified 13 patients with MM and t(11;14)(q13;q32) determined by standard cytogenetic analysis: in 10 patients the abnormality was detected at the time of relapse (three with previously normal results of cytogenetic examination). At the time the translocation was detected, plasma cell (PC) leukaemia was clinically diagnosed in two patients. The median number of circulating PCs, as determined by the cytoplasmic immunofluorescence of T-cell-depleted peripheral blood mononuclear cells, was 1.1x10(9)/l (mean 1.74; range 0.0017-6.26x10(9)/l). On linear regression analysis there was a strong correlation between the number of circulating PCs and the number of bone marrow PCs. The median survival after demonstration of the translocation was 8.1 months. Of all patients, 10 died of disease progression and three were alive. Patients with MM who have t(11;14)(q13;q32) seem to have an aggressive clinical course, even when the abnormality is detected at the time of diagnosis, with evidence of many circulating PCs.
Quality-Temporal Transcoder Driven by the Jerkiness (2005)

We propose a new video homogeneous transcoding architecture DCT-based which relies on both quality and temporal reduction techniques. The frame layer control is driven by a new indicator, the jerkiness, which represents the user perception of the movement which affects a video stream. The proposed transcoder can meet the constraints of a real-time communication and it has been extensively tested under different conditions
Markers of Rubella Virus Strains in RK <sub>13</sub> Cell Culture (1969)

When tested on RK(13) cell cultures, strains of rubella virus could be differentiated by their ability to form small or large plaques. Large plaques were produced by the HPV-77 and Cendehill strains, and also by a laboratory stock strain (West Point), after only 14 passages in RK(13) culture. Five wild-type rubella viruses, isolated and passaged only a few times in African green monkey kidney tissue culture, grew well in RK(13) cell culture, but they were sensitive to agar inhibitors and, therefore, formed small plaques. On the other hand, RA27/3, an attenuated strain grown in WI-38 human fibroblast cells, developed low titers in RK(13) cells and also produced small plaques. We concluded that the morphological differences between small-plaque and large-plaque viruses depended on their sensitivity to agar inhibitors and on the pH of the medium during plaque formation.
Polymer diffusion as a probe of damage in ion or plasma etching (1990)

Dry etching of polystyrene (PS) with oxygen, using ion beams or plasmas is found to affect the diffusion characteristics of molten PS. Four different techniques, reactive ion beam etching (RIBE), reactive ion etching (RIE), and plasma etching in barrel and downstream reactors are used. Polymer molecules lying near the surface of an etched sample are found to have been immobilized, and thus unable to diffuse. The quantity of material affected in this manner is found to increase with polymer molecular weight, and to be greater in samples etched by RIBE and RIE than in the pure plasma methods. Etching is also found to reduce the permeability of the sample surface to diffusion by unetched polymers. The permeability is found to decrease with the penetrant polymer’s molecular weight, and to decrease more drastically in RIBE and RIE treated samples than the plasma treated samples. Surface wrinkling of RIBE samples upon annealing above the glass transition temperature is also seen. The results are found to yield a consistent picture of polymer damage during dry etching consisting of crosslinking and chain scission. These experiments demonstrate the utility of polymer diffusion in the characterization of topological damage to polymer molecules.
Enhanced detection of nitrogen dioxide via combined heating and pulsed UV operation of indium oxide nano-octahedra (2016)

We report on the use of combined heating and pulsed UV light activation of indium oxide gas sensors for enhancing their performance in the detection of nitrogen dioxide in air. Indium oxide nano-octahedra were synthesized at high temperature (900 °C) via vapour-phase transport and screen-printed onto alumina transducers that comprised interdigitated electrodes and a heating resistor. Compared to the standard, constant temperature operation of the sensor, mild heating (e.g., 100 °C) together with pulsed UV light irradiation employing a commercially available, 325 nm UV diode (square, 1 min period, 15 mA drive current signal), results in an up to 80-fold enhancement in sensitivity to nitrogen dioxide. Furthermore, this combined operation method allows for making savings in power consumption that range from 35% to over 80%. These results are achieved by exploiting the dynamics of sensor response under pulsed UV light, which convey important information for the quantitative analysis of nitrogen dioxide.
Motion-Guided Cascaded Refinement Network for Video Object Segmentation (2019)

In this work, we propose a motion-guided cascaded refinement network for video object segmentation. By assuming the foreground objects show different motion patterns from the background, for each video frame we apply an active contour model on optical flow to coarsely segment the foreground. The proposed Cascaded Refinement Network (CRN) then takes as guidance the coarse segmentation to generate an accurate segmentation in full resolution. In this way, the motion information and the deep CNNs can complement each other well to accurately segment the foreground objects from video frames. To deal with multi-instance cases, we extend our method with a spatial-temporal instance embedding model that further segments the foreground regions into instances and propagates instance labels. We further introduce a single-channel residual attention module in CRN to incorporate the coarse segmentation map as attention, which makes the network effective and efficient in both training and testing. We perform experiments on popular benchmarks and the results show that our method achieves state-of-the-art performance with high time efficiency.
Digital transmission building blocks (1980)

This paper will provide an overview of some of the specific hardware subsystems and systems used to provide digital transmission between telephone buildings and to interconnect customers to telephone central offices.
In vitro expression of the first capsule gene of Streptococcus pneumoniae, cpsA, is associated with serotype-specific colonization prevalence and invasiveness (2007)

The polysaccharide capsule protects Streptococcus pneumoniae from phagocytosis during invasive infection, but inhibits adherence. Serotypes vary in their tendency to colonize the nasopharynx or cause invasive infection, and differences in capsule expression may play a role. Expression of the first gene of the capsule operon, cpsA, during in vitro growth of 43 clinical isolates representing 14 common pneumococcal serotypes was compared using quantitative RT-PCR. Serotypes associated with invasive infection (1, 4, 5, 7F, 8 and 14) expressed an average of twofold (P=0.0003) more cpsA than serotypes associated with nasopharyngeal colonization (6A, 6B, 9V, 15, 18C, 19F, 23F and 33). There was no difference in cpsA expression in response to growth under environmental oxygen or anaerobic conditions between the invasive and colonizing transparent strains tested: oxygen concentration did not affect cpsA expression in either the invasive or the colonizing transparent strains. Expression of cpsA at OD(600) 0.6 tended to be greater in strains with a longer lag phase during in vitro growth (P=0.07). Therefore, cpsA expression under ambient oxygen concentrations correlates with serotype-specific invasiveness and is inversely associated with the prevalence of serotype-specific carriage.
Estudo sobre a aplicacao da prova piagetiana de escoamento do liquido para avaliacao da nocao temporal (2007)

O presente artigo trata da avaliacao da concepcao de tempo do sujeito epistemico. De acordo com a epistemologia genetica, a construcao da nocao de tempo requer a coordenacao das operacoes de ordem dos acontecimentos e de imbricacao das duracoes. Nossos estudos demonstram que a prova do escoamento do liquido proposta por Piaget e um instrumento de avaliacao da nocao temporal muito adequado porque possibilita verificar empiricamente como o sujeito esta coordenando suas acoes mentais em relacao a concepcao de tempo no decorrer do seu desenvolvimento cognitivo. Palavras-chave: Nocao de tempo. Desenvolvimento cognitivo. Epistemologia genetica.
Chiral Separations of Polar Compounds by Hydrophilic Interaction Chromatography with Evaporative Light Scattering Detection (2000)

The chiral separations of drug substances and underivatized amino acids were demonstrated in this study through the use of hydrophilic interaction chromatography (HILIC). The polar character of the model compounds presented challenges for their analysis by traditional modes of chromatography, but through the employment of multimodal chromatography utilizing the HILIC mechanism and cyclodextrin- or teicoplanin-derivatized stationary phases, effective resolution was achieved. The analytes lacked sufficient ultraviolet chromophores, requiring their determination by evaporative light scattering detection. HILIC was demonstrated to represent a novel technique for the facilitation of chiral chromatography by providing an environment of solubility and retention that could not be achieved through the use of the traditional methods of reversed-phase, normal-phase, or polar organic mode.
Laser dynamical reservoir computing with consistency: an approach of a chaos mask signal (2016)

We numerically investigate reservoir computing based on the consistency of a semiconductor laser subjected to optical feedback and injection. We introduce a chaos mask signal as an input temporal mask for reservoir computing and perform a time-series prediction task. We compare the errors of the task obtained from the chaos mask signal with those obtained from other digital and analog masks. The performance of the prediction task can be improved by using the chaos mask signal due to complex dynamical response.
Analysis of Eight Capsaicinoids in Peppers and Pepper-Containing Foods by High-Performance Liquid Chromatography and Liquid Chromatography−Mass Spectrometry (2005)

Diverse procedures have been reported for the isolation and analysis of secondary metabolites called capsaicinoids, pungent compounds in the fruit of the Capsicum (Solanaceae) plant. To further improve the usefulness of high-performance liquid chromatography (HPLC), studies were carried out on the analysis of extracts containing up to eight of the following capsaicinoids: capsaicin, dihydrocapsaicin, homocapsaicin-I, homocapsaicin-II, homodihydrocapsaicin-I, homodihydrocapsaicin-II, nonivamide, and nordihydrocapsaicin. HPLC was optimized by defining effects on retention times of (a) the composition of the mobile phase (acetonitrile/0.5% formic acid in H2O), (b) the length of the Inertsil column, and (c) the capacity values (k) of the column packing. Identification was based on retention times and mass spectra of individual peaks. Quantification was based on the UV response at 280 nm in HPLC and recoveries from spiked samples. The method (limit of detection of approximately 15-30 ng) was successfully used to quantify capsaicinoid levels of parts of the pepper fruit (pericarp, placenta, seeds, and in the top, middle, and base parts of whole peppers) in 17 species of peppers and in 23 pepper-containing foods. The results demonstrate the usefulness of the method for the analysis of capsaicinoids ranging from approximately 0.5 to 3600 microg of capsaicin equiv/g of product. The water content of 12 fresh peppers ranged from 80.8 to 92.7%. The described freeze-drying, extraction, and analysis methods should be useful for assessing the distribution of capsaicinoids in the foods and in defining the roles of these biologically active compounds in the plant, the diet, and medicine.
Anodic stripping voltammetry as an analytical tool (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnodic stripping voltammetry as an analytical toolJoseph WangCite this: Environ. Sci. Technol. 1982, 16, 2, 104A–109APublication Date (Print):February 1, 1982Publication History Published online30 May 2012Published inissue 1 February 1982https://pubs.acs.org/doi/10.1021/es00096a724https://doi.org/10.1021/es00096a724research-articleACS PublicationsCopyright © 1982 American Chemical SocietyRequest reuse permissionsArticle Views281Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Improved current performance of CMOSFETs with nitrogen incorporated HfO/sub 2/-Al/sub 2/O/sub 3/ laminate gate dielectric (2003)

For the first time, we integrated poly-Si gate CMOSFETs with nitrogen incorporated HfO/sub 2/-Al/sub 2/O/sub 3/ laminate (HfAlON) as gate dielectrics. Both low gate leakage currents (0.1 mA/cm/sup 2/ at V/sub g/=+1.0 V) and low EOT (15.6 /spl Aring/) sufficiently satisfy the specifications (EOT=12/spl sim/20 /spl Aring/, J/sub g/=2.2 mA/cm/sup 2/) estimated by ITRS for low power applications. By in-situ 3 step post-deposition annealing, approximately 17 at.% nitrogen is incorporated at the HfAlON/Si interface. In-situ 3 step post-deposition annealing decreases metallic Hf bonding, which exists at the HfO/sub 2/-Al/sub 2/O/sub 3/ laminate/Si interface. As a result, we can suppress C-V hysteresis and improve current performance. Finally, well-behaved 100 nm CMOSFET devices are achieved. The measured saturation currents at 1.2 V V/sub dd/ are 585 /spl mu//spl Aring///spl mu/m (I/sub off/= 10 nA//spl mu/m) for nMOSFET and 265 /spl mu/A//spl mu/m (I/sub off/=10 nA//spl mu/m) for pMOSFET, which are approximately 80% of those of nitrided SiO/sub 2/. In terms of I/sub on/-I/sub off/ characteristics of n/pMOSFETs, these results represent the best current performance compared with previous reports for poly-Si gate CMOSFETs with high-k gate dielectrics.
Finite elements: Theory and application (1988)

Recent advances in FEM techniques and applications are discussed in reviews and reports presented at the ICASE/LaRC workshop held in Hampton, VA in July 1986. Topics addressed include FEM approaches for partial differential equations, mixed FEMs, singular FEMs, FEMs for hyperbolic systems, iterative methods for elliptic finite-element equations on general meshes, mathematical aspects of FEMS for incompressible viscous flows, and gradient weighted moving finite elements in two dimensions. Consideration is given to adaptive flux-corrected FEM transport techniques for CFD, mixed and singular finite elements and the field BEM, p and h-p versions of the FEM, transient analysis methods in computational dynamics, and FEMs for integrated flow/thermal/structural analysis.
Jacobian integration method increases the statistical power to measure gray matter atrophy in multiple sclerosis (2013)

Gray matter atrophy provides important insights into neurodegeneration in multiple sclerosis (MS) and can be used as a marker of neuroprotection in clinical trials. Jacobian integration is a method for measuring volume change that uses integration of the local Jacobian determinants of the nonlinear deformation field registering two images, and is a promising tool for measuring gray matter atrophy. Our main objective was to compare the statistical power of the Jacobian integration method to commonly used methods in terms of the sample size required to detect a treatment effect on gray matter atrophy. We used multi-center longitudinal data from relapsing-remitting MS patients and evaluated combinations of cross-sectional and longitudinal pre-processing with SIENAX/FSL, SPM, and FreeSurfer, as well as the Jacobian integration method. The Jacobian integration method outperformed these other commonly used methods, reducing the required sample size by a factor of 4-5. The results demonstrate the advantage of using the Jacobian integration method to assess neuroprotection in MS clinical trials.
Empirical Relation between Superconductivity and the Number of Valence Electrons per Atom (1955)

The relation between the transition temperature of a superconductor and its number of valence electrons/atom has been investigated. Optimum conditions for the occurrence of superconductivity seem to exist for 5 and 7 valence electrons/atom.
The Poxvirus A35 Protein Is an Immunoregulator (2009)

It was shown previously that the highly conserved vaccinia virus A35 gene is an important virulence factor in respiratory infection of mice. We show here that A35 is also required for full virulence by the intraperitoneal route of infection. A virus mutant in which the A35 gene has been removed replicated normally and elicited improved antibody, gamma interferon-secreting cell, and cytotoxic T-lymphocyte responses compared to wild-type virus, suggesting that A35 increases poxvirus virulence by immunomodulation. The enhanced immune response correlated with an improved control of viral titers in target organs after the development of the specific immune response. Finally, the A35 deletion mutant virus also provided protection from lethal challenge (1,000 50% lethal doses) equal to that of the wild-type virus. Together, these data suggest that A35 deletion viruses will make safer and more efficacious vaccines for poxviruses. In addition, the A35 deletion viruses will serve as improved platform vectors for other infectious diseases and cancer and will be superior vaccine choices for postexposure poxvirus vaccination, as they also provide improved kinetics of the immune response.
Detection for binary transmission in a mixture of Gaussian noise and impulsive noise modeled as an alpha-stable process (1994)

The impact of nonGaussian impulsive noise combined with Gaussian noise on the performance of the binary transmission is analyzed. The impulsive noise is modeled as an alpha-stable process. The probability of error for optimum, linear and nonlinear receivers is derived. The proposed nonlinear detectors show substantial improvements in performance compared to linear ones. The obtained results will be useful in performance evaluation of digital communication links subject to Gaussian and impulsive noises.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Context-aware middleware solutions for anytime and anywhere emergency assistance to elderly people (2006)

The growing percentage of elderly people in society calls for novel healthcare support services to enhance elders' daily life independence in indoor and outdoor environments. Ubiquitous technologies create significant opportunities not only for indoor, but also for outdoor anytime and anywhere assistance. However, outdoor emergency assistance requires that we address several challenging aspects, from elder location tracking and health condition monitoring to the formation of ad hoc assistance groups capable of assisting elders in need of help. This article focuses on the creation and management of outdoor assistance teams and proposes a group management system, AGAPE, that exploits visibility of location and group/user/device profile information as a key principle to trigger and control the team formation and team member interactions required to coordinate emergency activities.
Conformation of the mucopolysaccharides. X-ray fibre diffraction of heparin (1973)

Oriented films of the sodium salt of heparin crystallize in a triclinic unit cell. The X-ray diffraction results favour a tetrasaccharide covalent repeating sequence but the measured molecular repeat of 1.59nm is inconsistent with all alpha-(1-->4)(1ax-->4eq)-glycosidic linkages as generally accepted. Three models are proposed for the molecular shape of heparin, which depend on the chair conformation adopted by the hexuronic acid moieties. Model I has both uronic acids in the C1 chair form, model II has one uronic acid in each of the C1 and 1C chairs and model III has both in the 1C chair form. The merits of these models are discussed.
Implicit net-to-gross in the petrophysical characterization of thin-layered reservoirs (2006)

A new workflow has been devised to characterize the petrophysical properties of two, thin-layered, heterolithic log facies from a turbidite reservoir. The methodology is based on a published modelling technique that enables an extremely accurate reconstruction of the fine-scale lithological and sedimentological reservoir heterogeneities and a thorough integration of petrophysical data from core plugs. A large number of fine-scale rock models (geometrical grids) are: (1) stochastically generated to investigate the variability of the sedimentological features observed in cores; and (2) stochastically populated with porosity and permeability values of the pure lithological components (sandstone, siltstone and mudstone) to generate petrophysical grids. The petrophysical grids are subsequently upscaled using analytical and flow-based techniques, thus providing distributions of porosity, horizontal permeability and vertical permeability that are further analysed to characterize the aforementioned log facies. The results obtained using this workflow are exhaustive, in the sense that they implicitly take into account all of the possible ranges of variation of ‘net-reservoir’ (sandstone and siltstone) and ‘non-net-reservoir’ (mudstone) lithologies. The use of net-to-gross in petrophysical characterization is thus made redundant.
Geometric Computations with Interval and New Robust Methods: Applications in Computer Graphics, GIS and Computational Geometry (2003)

This undergraduate and postgraduate text will familiarise readers with interval arithmetic and related tools to gain reliable and validated results and logically correct decisions for a variety of geometric computations plus the means for alleviating the effects of the errors. It also considers computations on geometric point-sets, which are neither robust nor reliable in processing with standard methods. The authors provide two effective tools for obtaining correct results: (a) interval arithmetic, and (b) ESSA the new powerful algorithm which improves many geometric computations and makes th