gebhart/patrepeval huggingface dataset:
The Creative School (2003)

This book is about a unique school. It is a school that, despite the increasing pressure put upon it by changes in the curriculum and the organisation of education, has managed to successfully maintain the creative values that have won it international and governmental recognition. Written for teachers and headteachers who want to encourage creativity in their schools and classrooms, the book describes: the school's culture of holism its use and appreciation of its grounds and environment for learning its innovative approaches to curriculum organisation its appropriation of national initiatives such as the literacy and numeracy hours its creative teaching and learning through the eyes of observers, teachers, children and parents. The success of Coombes School shows that it is possible to combine externally imposed prescription with a set of personal beliefs and values - making a real difference to the quality of teaching and learning. This is a truly inspirational read.
Mechanisms Controlling Corpus Luteum Function in Sheep, Cows, Nonhuman Primates, and Women Especially in Relation to the Time of Luteolysis (1988)

THE CORPUS luteum (CL) of sheep, cows, and primates consists primarily of luteinized granulosa and thecal cells (1, 2). Luteal cells synthesized and secrete progesterone, and in certain species, estrogen. There appear to be two types of luteal steroidogenic cells in many species, including the sheep (3–5), cow (6–8), rhesus monkey (9, 10), and human female (11–13) which can be distinguished on the basis of their size and morphology; these have been presumed to be derived separately from granulosa and thecal cells and have been assigned different endocrine functions in the sheep (14). By determining the function of these cells at different stages during the life of the CL it may be possible to identify factors causing luteolysis and those required for the maintenance of pregnancy. The primary function of the CL is generally considered to be the production of the steroid progesterone, which prepares the uterine endometrium for implantation and maintains early pregnancy. In order to fulfill this role, the CL must remain viable for a specific period in gestation (Table 1); thereafter [at the time of the luteoplacental shift; Csapo (23)] in most species, the placenta assumes the role of progesterone synthesis for the remainder of the pregnancy and the CL is expendable. If fertilization and implantation do not occur, ovulatory cycles resume only after luteal function ceases; this emphasizes a second role of the CL, that of blocking ovulation.
Moving obstacle detection in highly dynamic scenes (2009)

We address the problem of vision-based multi-person tracking in busy pedestrian zones using a stereo rig mounted on a mobile platform. Specifically, we are interested in the application of such a system for supporting path planning algorithms in the avoidance of dynamic obstacles. The complexity of the problem calls for an integrated solution, which extracts as much visual information as possible and combines it through cognitive feedback. We propose such an approach, which jointly estimates camera position, stereo depth, object detections, and trajectories based only on visual information. The interplay between these components is represented in a graphical model. For each frame, we first estimate the ground surface together with a set of object detections. Based on these results, we then address object interactions and estimate trajectories. Finally, we employ the tracking results to predict future motion for dynamic objects and fuse this information with a static occupancy map estimated from dense stereo. The approach is experimentally evaluated on several long and challenging video sequences from busy inner-city locations recorded with different mobile setups. The results show that the proposed integration makes stable tracking and motion prediction possible, and thereby enables path planning in complex and highly dynamic scenes.
STUDY ON THE EFFICACY OF NOSOCOMIAL INFECTION CONTROL (SENIC PROJECT): SUMMARY OF STUDY DESIGN (1980)

With the emergence of nosocomial infections as a serious problem among US hospitals, the Center for Disease Control undertook in 1974 a nationwide study to evaluate approaches to infection control. The three-phased project, now known as the Study on the Efficacy of Nosocomial Infection Control, or SENIC Project, was designed with three primary objectives: 1) to determine whether (and, if so, to what degree) the implementation of infection surveillance and control programs (ISCPs) has lowered the rate ofnosocomi al infection, 2) to describe the current status of ISCPs and infection rates, and 3) to demonstrate the relationships among characteristics of hospitals and patients, components of ISCPs, and changes in the infection rate. With data collection completed in a nationally representative sample of hospitals, analysis is underway to identify approaches to infection control that are most effective for the least cost to hospitals and to point out additional specific questions to be answered by future research.
Growth inhibition of <i>Mycobacterium bovis</i> by IFN-γ stimulated macrophages: regulation by endogenous tumor necrosis factor-α and by IL-10 (1994)

Murine bone marrow-derived macrophages (BMM) are able to inhibit the intracellular growth of Mycobacterium bovis and Mycobacterium tuberculosis H37Rv after activation with recombinant (r) IFN and growth inhibition is mediated by reactive nitrogen intermediates (RNI) derived from L-arginine. We now demonstrate that tumor necrosis factor (TNF)-alpha acts as an endogenous cofactor in the induction of mycobacterial growth inhibition. TNF-alpha was produced by BMM stimulated with rIFN-gamma and infected with mycobacteria, and a specific antiserum to TNF-alpha inhibited rIFN-gamma-induced production of RNI as well as growth inhibition of M. bovis. IL-10, a cytokine which suppresses antimycobacterial macrophage functions, was also produced by BMM activated with rIFN-gamma and infected with M. bovis. IFN-gamma-induced production of TNF-alpha and of reactive nitrogen intermediates as well as mycobacterial growth inhibition were inhibited by exogenous IL-10, but only when given prior to IFN-gamma stimulation. We conclude that the outcome of mycobacterial infection is regulated by a coordinate interplay between IFN-gamma, TNF-alpha and IL-10.
Vascular endothelial growth factor is a neurotrophic factor which stimulates axonal outgrowth through the flk‐1 receptor (2000)

Vascular endothelial growth factor (VEGF) is an angiogenic factor that stimulates axonal outgrowth. Here we used in situ hybridization and immunocytochemistry to study the VEGF receptor flk-1 in cultured superior cervical ganglia (SCG) and dorsal root ganglia (DRG) from adult mice, and also the effects of VEGF on regeneration in vitro. Neurons in both ganglia contained the flk-1 receptor and showed an increased mRNA expression and immunoreactivity for flk-1 after 48 h in culture. In SCG, but not in DRG, double immunostaining for flk-1 and VEGF revealed coexpression in many neurons, implying that VEGF may exert both autocrine and paracrine actions. One proportion of the flk-1-positive neurons in DRG stained positive for the large neuron marker RT97 and another proportion expressed calcitonin gene-related peptide (CGRP). Small IB4-positive neurons were devoid of flk-1 immunoreactivity. Most flk-1-positive neurons in the DRG, but not in the SCG, were also immunoreactive to neuropilin-1. VEGF was found to stimulate axonal outgrowth from DRG, both by an action on the growing axons and the nerve cell bodies. The latter effect could be mediated by retrograde axonal transport as revealed by the use of a two compartment system to assay axonal outgrowth. We also found that the VEGF-induced axonal outgrowth was blocked by the flk-1 inhibitor SU5416. The results strongly suggest that VEGF acts as a neurotrophic factor and plays an important role during the regeneration of peripheral nerves.
Effect of hydrogen on the strength and microstructure of selected ceramics (1990)

Ceramics in monolithic form and as composite constituents in the form of fibers, matrices, and coatings are currently being considered for a variety of high-temperature applications in aeronautics and space. Many of these applications involve exposure to a hydrogen-containing environment. The compatibility of selected ceramics in gaseous high-temperature hydrogen is assessed. Environmental stability regimes for the long term use of ceramic materials are defined by the parameters of temperature, pressure, and moisture content. Thermodynamically predicted reactions between hydrogen and several monolithic ceramics are compared with actual performance in a controlled environment. Morphology of hydrogen attack and the corresponding strength degradation is reported for silicon carbide, silicon nitride, alumina, magnesia, and mullite.
The force model of wireless active actuation for capsule endoscope in the GI tract (2007)

We presents a new closed loop approach for the active actuation of wireless capsule endoscope inside the human GI tract. A magnet is enclosed in the capsule, and its position, orientation, and movement are detected by a magnetic localization system. To actuate the capsule, an external rotative magnetic field is applied around human body such that a driving force is created in the capsule by the magnet. Through the spiral structure on the capsule surface, the capsule is rotated to move forward or backward with the aid of mucus of the GI tract. According to the hydromechanical lubrication theory and Newton viscous law, we build the traction force model, the friction force model and the locomotion speed model. In this paper, the simulation results of all these three mathematical models are given, which will provide theoretical guide to design the spiral impeller structure of the capsule and estimate the motion force induced by external magnetic field.
Understanding the Influence of Social Identity on Social Support Seeking Behaviors in Virtual Healthcare Community (2010)

ICIS 2010 Proceedings - Thirty First International Conference on Information Systems
Behavior of Plasticizers in Vinyl Chloride-Acetate Resins (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBehavior of Plasticizers in Vinyl Chloride-Acetate ResinsM. C. Reed and Leonard ConnorCite this: Ind. Eng. Chem. 1948, 40, 8, 1414–1422Publication Date (Print):August 1, 1948Publication History Published online1 May 2002Published inissue 1 August 1948https://doi.org/10.1021/ie50464a016RIGHTS & PERMISSIONSArticle Views43Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (904 KB) Get e-Alerts
Micro-plasma field-effect transistors (2012)

We designed, fabricated and tested new microplasma FET (MOPFET) devices that operate inside RF helium plasma that generated at atmospheric pressure. Unlike normal FETs, micro-plasma FETs uses electrons and ions as carriers. It has unique advantages over normal FETs in extreme conditions at high temperature and ionizing radiation in space and in a nuclear event. It also has potential applications in combustion engine sensors and diagnostic circuits. MOPFET can potentially operate with very few ions and have the additional potential of producing nano-scale switches and amplifiers. The plasma for our MOPFET was separately generated and sustained using an RF plasma source. Thus, for the first time we achieved small voltage (5-10V) plasma switches and amplifiers. We have developed concentrated and distributed plasma sources suitable for different sizes of integrated MOPFET circuits.
Collagen Extracts Derived From Young and Aged Mice Demonstrate Different Structural Properties and Cellular Effects in Three-Dimensional Gels (2010)

Three-dimensional (3D) type I collagen gels are increasingly utilized to simulate extracellular matrix (ECM) in vivo, but little is known about the effects of age on this model. Collagen was extracted from young (4-6 months) and aged (20-24 months) mice tails and compared. The collagens appeared similar by electrophoresis. However, relative to young, aged collagen formed fibrils slower and generated 3D gels with smaller diameter, less dense fibrils (75 vs 34 nm diameter and 8 vs 3.5% area, for young and aged respectively, p < 0.02). Correspondingly, aged collagen gels were more malleable and contractible (5% vs 19% compression, p < .02, and 73% vs 15.5% area, p < .01, for young and aged, respectively). Fibroblasts cultured within young and aged collagen gels had differential expression of a limited number of genes and proteins corresponding to specific integrins and matrix components. In summary, collagen extracted from young and aged mice is an effective means to examine the influence of aging on functional properties of ECM that are relevant in vivo.
(.mu.-Ethylenediaminetetraacetato)(.mu.-oxo)(.mu.-sulfido)bis(oxotungstate(V)): the first crystallographically characterized complex containing the W2(O)2(.mu.-O)(.mu.-S) unit (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT(.mu.-Ethylenediaminetetraacetato)(.mu.-oxo)(.mu.-sulfido)bis(oxotungstate(V)): the first crystallographically characterized complex containing the W2(O)2(.mu.-O)(.mu.-S) unitShinji Ikari, Yoichi Sasaki, and Tasuku ItoCite this: Inorg. Chem. 1989, 28, 3, 447–451Publication Date (Print):February 1, 1989Publication History Published online1 May 2002Published inissue 1 February 1989https://pubs.acs.org/doi/10.1021/ic00302a015https://doi.org/10.1021/ic00302a015research-articleACS PublicationsRequest reuse permissionsArticle Views70Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Copy number of <i>FCGR3B,</i> which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake (2008)

Copy number (CN) variation (CNV) has been shown to be common in regions of the genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity. Low CN of FCGR3B has recently been associated with systemic lupus erythematosus (SLE). FcgammaRIIIb is a glycosylphosphatidylinositol-linked, low affinity receptor for IgG found predominantly on human neutrophils. We present novel data demonstrating that both in a family with FcgammaRIIIb-deficiency and in the normal population, FCGR3B CNV correlates with protein expression, with neutrophil uptake of and adherence to immune complexes, and with soluble serum FcgammaRIIIb. Reduced FcgammaRIIIb expression is thus likely to contribute to the impaired clearance of immune complexes, which is a feature of SLE, explaining the association between low FCGR3B CNV and SLE that we have confirmed in a Caucasian population. In contrast, antineutrophil cytoplasmic antibody-associated systemic vasculitis (AASV), a disease not associated with immune complex deposition, is associated with high FCGR3B CN. Thus, we define a role for FCGR3B CNV in immune complex clearance, a function that may explain why low FCGR3B CNV is associated with SLE, but not AASV. This is the first report of an association between disease-related gene CNV and variation in protein expression and function that may contribute to autoimmune disease susceptibility.
Evaluating the Benefits of Octree-based Indexing for Lidar Data (2012)

Very large true three-dimensional (3D) point datasets, as opposed to the previously common 2.5D data sets, are progressively more common nowadays, such as from Light Detection and Ranging (LiDAR). Increasingly, attempts are made to exploit these 3D point data sets beyond mere visualization. However, current Spatial Information Systems provide only limited 3D support. Even commercial systems advertising in-built, 3D data types provide only minimal functionality. Particularly, there is no effective means of indexing large 3D point datasets, which is crucial for efficient analysis and engineering usage. Also many datasets are information rich (e.g. contain color or some other associated semantic information), which has yet to be fully exploited. This paper presents the implementation in a commercial spatial database of a spatial indexing technique using an octree data structure and highlights its advantages for sparse, as well as uniformly distributed, aerial LiDAR data. The implementation outperforms an existing r-tree index within the software, and offers additional functionality of attribute-based 3D grouping.
Virulence of an Escherichia coli O157:H7 sorbitol-positive mutant (1993)

Virulence and pathogenicity of an Escherichia coli O157:H7 sorbitol-positive mutant were investigated with an infant rabbit animal model as well as a battery of in vitro assays. Total cell lysate protein profiles, outer membrane protein profiles, plasmid profiles, and levels of cytotoxic activity against Vero cells were similar in the wild-type and mutant strains. Both adhered to intestinal epithelial cells in culture and reacted with fluorescein isothiocyanate-labeled antiserum against E. coli O157:H7. The mutant appeared to be similar to the wild type in all respects except in its ability to ferment sorbitol. [14C]sorbitol uptake and sorbitol-6-phosphate dehydrogenase activities were notably increased in the mutant strain. Diarrhea developed in rabbits administered the wild-type strain and in those fed the sorbitol-positive mutant. There was greater bacterial attachment and mucosal damage in the cecum and large intestine than in the small intestine. Scanning electron microscopy revealed bacteria adhering as single cells and as aggregates closely associated with mucus. Mucosal lesions consisted of areas of tissue necrosis with sloughing of epithelial cells. By transmission electron microscopy, electron-dense necrotic epithelial cells were visible in areas where bacteria were present, and epithelial cell debris containing bacteria was observed between the villar luminal surfaces. Light microscopy of epithelial cells of intestinal sections of infected rabbits revealed noticeable vacuolation and spherical, pyknotic nuclei. These data indicate that the sorbitol-negative phenotype is not associated with the pathogenicity of E. coli O157:H7.
Metabolic Bone Disease in the Bariatric Surgery Patient (2010)

Bariatric surgery has proven to be a life-saving measure for some, but for others it has precipitated a plethora of metabolic complications ranging from mild to life-threatening, sometimes to the point of requiring surgical revision. Obesity was previously thought to be bone protective, but this is indeed not the case. Morbidly obese individuals are at risk for metabolic bone disease (MBD) due to chronic vitamin D deficiency, inadequate calcium intake, sedentary lifestyle, chronic dieting, underlying chronic diseases, and the use of certain medications used to treat those diseases. After bariatric surgery, the risk for bone-related problems is even greater, owing to severely restricted intake, malabsorption, poor compliance with prescribed supplements, and dramatic weight loss. Patients presenting for bariatric surgery should be evaluated for MBD and receive appropriate presurgical interventions. Furthermore, every patient who has undergone bariatric surgery should receive meticulous lifetime monitoring, as the risk for developing MBD remains ever present.
Future GNSS Signals (2008)

This special issue of the International Journal of Navigation and Observation deals with future global navigation satellite system (GNSS) signals. It is a timely issue in view of the current US GPS modernization efforts, the deployment of the EU’s Galileo, the replenishment of Russia’s GLONASS, and China’s plan to launch COMPASS. These systems, either individually or as a group, will provide tremendous availability, accuracy, and reliability enhancements to a consumer’s market that is growing at an annual doubledigit rate. Research is taking place not only to enhance the methods and algorithms to process the signals already in place but also to propose and optimize future signals and combinations thereof. The seven papers presented in this issue cover a variety of topics, ranging fromGalileo signal testing to signal multipath reduction, and represent a good cross-section of current activities in this area. A study of multipath performance of the initial Galileo signals transmitted by the GIOVEA satellite using actual data is described by Simsky et al., and a new generic approach called multiple gate delay tracking structures to reduce GNSS signal multipath is proposed and evaluated with different software approaches by Heikki Hurskainen et al. Also, Borio et al. discuss two strategies for the joint acquisition of data and pilot channels that are available on emerging signals. Shanmugam et al. present a short synchronization code design for future GNSS based on the optimization of specific performance criteria. Joint L/C-band code and carrier phase linear combination methods for Galileo are discussed by Henkel et al. Moreover, Lentmaier et al. discuss Bayesian time delay estimation based on particle filters for use in dynamic multipath environments. Finally, a comparison between Galileo CBOC candidates and BOC(1,1) signals in terms of detection performance is presented by Dovis et al.
Stabilization mechanism of nitrazepam supersaturated state in nitrazepam/Eudragit®EPO/saccharin solution revealed by NMR measurements (2015)

DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for everyone.
99mTc-NC100668, an agent for imaging venous thromboembolism: The effect of anticoagulant or thrombolytic therapy on the uptake and retention of radioactivity in blood clots in vivo (2006)

This study has demonstrated that the uptake and retention of (99m)Tc-NC100668 into blood clots in the rat model of deep vein thrombosis is rapid and maintained over at least a 4 h. post-injection period. It has been shown that (99m)Tc-NC100668 is retained in blood clots even in the presence of therapeutic doses of those anticoagulant and thrombolytic therapies typically used to treat pulmonary embolism and venous thrombosis.