gebhart/patrepeval huggingface dataset:
Composing Services for Third-party Service Delivery (2009)

This paper proposes a model-based technique for lowering the entrance barrier for service providers to register services with a marketplace broker, such that the service is rapidly configured to utilize the brokerpsilas local service delivery management components. Specifically, it uses process modeling for supporting the execution steps of a service and shows how service delivery functions (e.g. payment points) ldquolocalrdquo to a service broker can be correctly configured into the process model. By formalizing the different operations in a service delivery function (like payment or settlement) and their allowable execution sequences (full payments must follow partial payments), including cross-function dependencies, it shows how through tool support, the non-technical user can quickly configure service delivery functions in a consistent and complete way.
Hydrogenated Amorphous Germanium Optical Fiber (2015)

Hydrogenated amorphous germanium step index optical fibers have been fabricated by high pressure chemical vapor deposition ensuring high hydrogen content thereby passivizing dangling bonds. These fibers can be used for various infrared applications.
Structure determination of micelle-like intermediates in amyloid β-protein fibril assembly by using small angle neutron scattering (2001)

Increasing evidence supports the hypothesis that amyloid beta-protein (Abeta) assembly is a key pathogenic feature of Alzheimer's disease. Thus, understanding the assembly process offers opportunities for the development of strategies for treating this devastating disease. In prior studies, Abeta was found to form micelle-like aggregates under acidic conditions. These structures exhibited an average observed hydrodynamic radius of 7 nm. They were found to be in rapid equilibrium with Abeta monomers or low molecular weight oligomers, and were centers of fibril nucleation. Here the technique of small angle neutron scattering has been used to determine the structure of these Abeta micelles. The data reveal that the micellar assemblies comprise 30-50 Abeta monomers and have elongated geometries. The best fit of the data to a uniform spherocylinder yields a radius approximately 2.4 nm and cylinder length approximately 11 nm. These structure parameters remain constant over more than a decade in concentration range. The concentration independence of the length of the cylindrical aggregate indicates the presence of an internal nonrepetitive structure that spans the entire length of the Abeta assembly.
Local Mobility Anchor (LMA) Discovery for Proxy Mobile IPv6 (2011)

Large Proxy Mobile IPv6 deployments would benefit from a
functionality, where a Mobile Access Gateway could dynamically
discover a Local Mobility Anchor for a Mobile Node attaching to a
Proxy Mobile IPv6 domain. The purpose of the dynamic discovery
functionality is to reduce the amount of static configuration in the
Mobile Access Gateway. This specification describes a number of
possible dynamic Local Mobility Anchor discovery solutions.
MEMS Optical Scanners for Microscopes (2004)

Microelectromechanical systems (MEMS) optical scanners have been around for more than two decades. Various applications have been presented, but few of them have advanced to the commercial level to date due to the difficulties of combination of optics and MEMS devices. This paper presents our activities of investigating MEMS scanner applications related to microscopic imaging. First, we started with developing a millimeter-sized one-dimensional scanner for commercially available laser scanning microscope. This microscope with the MEMS scanner is now commercially available. In order to take advantage of the miniaturization capability of MEMS, the next step was to miniaturize the whole optics together with the scanners. Miniaturized confocal microscope with a two-dimensional (2-D) scanner has been developed, and its feasibility and key issues are clarified. Additionally, an alternative 2-D scanner capable of scanning wide angle has been prototyped and fundamental characterization showed a promising result. Throughout the study, feasibility of MEMS optical scanners for microscopes has been demonstrated.
Structural mechanism of high affinity Fcγ<scp>RI</scp> recognition of immunoglobulin G (2015)

Antibody-based immunotherapies are becoming powerful means of modern medicine for treating cancers and autoimmune diseases. The increasing popularity of antibody-based treatment demands a better understanding of antibody functions and in particular, their interaction with Fc receptors as effectiveness of antibodies often depends on their ability to activate or avoid effector cell functions through Fc receptors. Until recently, our understanding of antibody recognition by Fc receptors is based on the structures of low affinity Fc receptor in complex with Fc. These structural studies provided significant insights to our understanding of how an IgG antibody generally docks on Fcγ receptor and the requirement of immune complex formation for effector cell activations. They are less informative, however, to the molecular forces underlying the vast different affinities between antibodies and their Fcγ receptors. Recently, the structure of the high affinity FcγRI in complex with IgG-Fc has been determined. This review will focus on the knowledge learned from the high affinity complex structural work and a potential receptor-glycan interaction as an important contribution to the receptor affinity.
Supporting Drivers in Keeping Safe Speed in Adverse Weather Conditions by Mitigating the Risk Level (2013)

Overspeeding is both a cause and an aggravation factor of traffic accidents. Consequently, much effort is devoted to limiting overspeeding and, consequently, to increasing the safety of road networks. In this paper, a novel approach to computing a safe speed profile to be used in an adaptive intelligent speed adaptation (ISA) system is proposed. The method presents two main novelties. First, the 85th percentile of observed speeds (V85), estimated along a road section, is used as a reference speed, which is practiced and practicable in ideal conditions. Second, this reference speed is modulated in adverse weather conditions to account for reduced friction and reduced visibility distance. The risk is thus mitigated by modulating the potential severity of crashes by means of a generic scenario of accidents. Within this scenario, the difference in speed that should be applied in adverse conditions is estimated so that the highway risk is the same as in ideal conditions. The system has been tested on actual data collected on a French secondary road and implemented on a test track and a fleet of vehicles. The performed tests and the experiments of acceptability show a great interest for the deployment of such a system.
A distributed Newton method for Network Utility Maximization (2010)

Most existing work uses dual decomposition and subgradient methods to solve Network Utility Maximization (NUM) problems in a distributed manner, which suffer from slow rate of convergence properties. This work develops an alternative distributed Newton-type fast converging algorithm for solving network utility maximization problems with self-concordant utility functions. By using novel matrix splitting techniques, both primal and dual updates for the Newton step can be computed using iterative schemes in a decentralized manner with limited scalar information exchange. Similarly, the stepsize can be obtained via an iterative consensus-based averaging scheme. We show that even when the Newton direction and the stepsize in our method are computed within some error (due to finite truncation of the iterative schemes), the resulting objective function value still converges superlinearly to an explicitly characterized error neighborhood. Simulation results demonstrate significant convergence rate improvement of our algorithm relative to the existing subgradient methods based on dual decomposition.
University of Pennsylvania Radiocarbon Dates XVI (1974)

On two previous occasions we have published lists of 14 C results of precisely dated wood samples in Radiocarbon as per mil deviations (R, 1965, v 7, p 179–186; R, 1969, v 11, no. 2, p 469–481). We have also published a list of 14 C dates, consolidating all dated wood samples processed in our lab to July 1969 (Ralph and Michael, 1970).
On building a successful IPTV business model based on personalized IPTV content &#x00026; services (2009)

The Internet Protocol Television (IPTV) service provides rich multimedia services over IP networks and is widely believed to be the next killer application over the Internet. It is generating a lot of interest, especially in potential service providers who are eager to develop successful business models that will ensure their survival in this emerging market. We believe that the success of an IPTV business will depend to a large extent on the ability of the service providers to provide the right IPTV contents and services to the right subscribers, at the right time and in a way that is most convenient and appealing to the subscribers (more specifically, the end-users). In this paper, therefore, we present an IPTV business model, which we believe will guarantee service providers' success and survival. The business model is based on the efficient packaging, advertising and delivery of IPTV contents and services to end-users.
Flexible Filaments for <i>in Vivo</i> Imaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage (2009)

Shape effects of synthetic carriers are largely unexplored in vivo, although recent findings suggest that flexible filaments can persist in the circulation even if microns in length. Here, to better assess biodistribution, a near-infrared fluorophore (NIRF) was incorporated into such block copolymer "filomicelles", and both in vivo and ex vivo imaging show that the majority of these wormlike micelles remain in the circulation for at least a day after intravenous injection. NIRF imaging further suggests that filomicelles convect into a tumor and some fragments can penetrate into the tumor stroma. To assess a functional effect, the hydrophobic drug paclitaxel (tax) was loaded into both filomicelles and sonication-generated spherical micelles of the same copolymer. Intravenous injection of tax-loaded filomicelles nearly doubles the maximum tolerated dose of tax in normal mice compared to tax-loaded spherical micelles. In tumor-bearing mice, the higher dose of tax produces greater and more sustained tumor shrinkage and tumor cell apoptosis. These results thus begin to address mechanisms for how nonspherical carriers deliver both imaging agents and anticancer therapeutics to solid tumors.
The role of airborne proteins in atopic dermatitis. (2010)

Atopic dermatitis is a common, chronic skin condition. A subpopulation of patients may have cutaneous exposure to common airborne proteins exacerbating their disease through direct proteolytic activity, direct activation of proteinase-activated receptor-2 itch receptors, and immunoglobulin E binding. The most common airborne proteins significant in atopic dermatitis include house dust mites, cockroach, pet dander, and multiple pollens. The literature on atopy patch testing, skin-prick testing, and specific IgE is mixed, with greater support for the use of atopy patch test. Patients with airborne proteins contributing to their disease typically have lesions predominately on air-exposed skin surfaces including the face, neck, and arms; a history of exacerbations after exposure to airborne proteins; severe disease resistant to conventional therapies; and concurrent asthma. Treatment strategies include airborne protein avoidance, removal of airborne proteins from the skin, and barrier repair. Further research is needed to establish the benefit of allergen-specific immunotherapy.
Proton Grid Therapy: A Proof-of-Concept Study (2016)

In this work, we studied the possibility of merging proton therapy with grid therapy. We hypothesized that patients with larger targets containing solid tumor growth could benefit from being treated with this method, proton grid therapy. We performed treatment planning for 2 patients with abdominal cancer with the suggested proton grid therapy technique. The proton beam arrays were cross-fired over the target volume. Circular or rectangular beam element shapes (building up the beam grids) were evaluated in the planning. An optimization was performed to calculate the fluence from each beam grid element. The optimization objectives were set to create a homogeneous dose inside the target volume with the constraint of maintaining the grid structure of the dose distribution in the surrounding tissue. The proton beam elements constituting the grid remained narrow and parallel down to large depths in the tissue. The calculation results showed that it is possible to produce target doses ranging between 100% and 130% of the prescribed dose by cross-firing beam grids, incident from 4 directions. A sensitivity test showed that a small rotation or translation of one of the used grids, due to setup errors, had only a limited influence on the dose distribution produced in the target, if 4 beam arrays were used for the irradiation. Proton grid therapy is technically feasible at proton therapy centers equipped with spot scanning systems using existing tools. By cross-firing the proton beam grids, a low tissue dose in between the paths of the elemental beams can be maintained down to the vicinity of a deep-seated target. With proton grid therapy, it is possible to produce a dose distribution inside the target volume of similar uniformity as can be created with current clinical methods.
Edge wave visualization (1991)

Scattering mechanisms that involve edge waves are addressed. The behavior of edge waves and their interaction with flat perfectly conducting plates are depicted in the time domain through a visualization of surface currents that flow on the surface, as an incident Gaussian pulse of energy washes over the surface. Viewing these surface currents allows a very clear physical interpretation and appreciation of the scattering process.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Source Rock-Crude Oil Correlations: Alaskan North Slope: SOURCE ROCK EVALUATION AND BIOMARKERS (1985)

Seven of 9 oils for this study have experienced varying degrees of alteration. As a result, whole oil gas chromatography and other conventional analyses show little resemblance in composition. Gas chromatography-mass spectrometric analysis of sterane and terpane components of the oil and rock samples permitted the determination of genetic relationship among the rocks and oils. The North Slope oils can be divided into three groups by the sterane compositions and the sterane and terpane distribution patterns. Group 1 oils, which are least mature and generally referred to as Simpson-Umiat type (Magoon and Claypool, 1981) probably originated from the Lower Cretaceous pebble shale unit. Group 2 oils, reservoired in a wide range of geological formations ranging from Permo-Triassic to Cretaceous, were derived from either the Kingak Shale, the Shublik Formation, or possibly the Sadlerochit Group. Group 3, the most mature oil type, was probably sourced from the deeper Lisburne Group, from which no rock sample was included in this study.
Do exons code for structural or functional units in proteins? (2020)

In considering the origin and evolution of proteins, the possibility that proteins evolved from exons coding for specific structure-function modules is attractive for its economy and simplicity but is not systematically supported by the available data. However, the number of correspondences between exons and units of protein structure-function that have so far been identified appears to be greater than expected by chance alone. The available data also show (i) that exons are fairly limited in size but are large enough to specify structure-function modules in proteins; (ii) that the position of introns for homologous domains in the same gene is reasonably stable, but there is also evidence for mechanisms that alter the position or existence of introns; and (iii) that it is possible that the observed relationship of exons to protein structure represents a degenerate state of an ancestral correspondence between exons and structure-function modules in proteins.
Modeling of three-dimensional effects on temperature uniformity in rapid thermal processing of eight inch wafers (1994)

A three-dimensional steady-state model of the industry-standard AG Associates 4108 Heatpulse Rapid Thermal Processing system has been developed for the study of thermal uniformity across 8 inch wafers. The model combines radiation energy transfer among all solid surfaces in the chamber with energy transfer among the chamber materials and to the process ambient. Surfaces included are those of the tungsten filaments of the lamps, the silicon wafer, the polysilicon annular thermal guard ring, the quartz process tube, and the gold reflectors which surround the lamps and process tube. These surfaces are divided into approximately 4800 individual surface elements for the radiation transfer allowing very accurate thermal analysis. The model has previously been shown to provide very good agreement with experiment for temperature distributions across an 8 inch wafer. The model is presently used to make quantitative examinations of asymmetric effects occurring in a RTP chamber which cannot be examined by 2-dimensional models. Situations examined include the effect of nonuniform lamp power distributions. Also examined is tilting of the wafer with respect to the flow tube and reflective chamber.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
AN EQUIVALENT CIRCUIT MODELING METHOD FOR ULTRA-WIDEBAND ANTENNAS (2008)

This paper presents an effective modeling methodology for Ultra-wideband (UWB) antennas. The methodology is based on augmenting an existing narrow-band model with a macro-model while simultaneously perturbing component values of the narrow-band model. The narrow-band model is an empirical-based circuit and the macro-model described by rational functions is determined using data fitting approaches. The perturbation of component values of the narrow-band model is achieved by adjustments in SPICE. This method is demonstrated on the example of a 2.5 cm dipole antenna and a circular disc monopole antenna for UWB systems. Simulation results show that this methodology is effective over a wide bandwidth and suitable for modeling most UWB antennas.
Type- and Species-Selective Air Etching of Single-Walled Carbon Nanotubes Tracked with <i>in Situ</i> Raman Spectroscopy (2013)

The thermal oxidation of carbon nanotubes in air is investigated by in situ Raman spectroscopy. Etching rates are directly seen to be diameter, chirality, and type dependent. We directly track the evolution of bundled nanotube networks that undergo air etching from 300 to 600 °C. Some species are more robust than others. Changes to radial breathing mode (RBM) and G- peak structures suggest that metallic species etch away more rapidly, with smaller diameter semiconducting species etching more slowly and large diameter nanotubes, including semiconductors, etching last. The decay in integrated G and D band intensities is tracked and fit reasonably well with biexponential decay. The RBM evolution is better represented by a single exponential. All bands are fit to activation plots with RBMs showing significantly different rates.
Enantioselective Total Synthesis of Antifungal Agent Sch 38516 (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTEnantioselective Total Synthesis of Antifungal Agent Sch 38516Zhongmin Xu, Charles W. Johannes, Sarri S. Salman, and Amir H. HoveydaView Author Information Department of Chemistry, Merkert Chemistry Center, Boston College Chestnut Hill, Massachusetts 02167 Cite this: J. Am. Chem. Soc. 1996, 118, 44, 10926–10927Publication Date (Web):November 6, 1996Publication History Received31 July 1996Published online6 November 1996Published inissue 1 January 1996https://doi.org/10.1021/ja9626603Copyright © 1996 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1435Altmetric-Citations83LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (152 KB) Get e-AlertsSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Carbohydrates,Cyclization,Metathesis,Selectivity,Stereoselectivity Get e-Alerts
Program explorer: a program visualizer for C++ (1995)

Despite the obvious advantages of using object-oriented (O-O) program visualizers in system understanding and debugging, they are still rarely found in the programmers's tool box. One reason for this that such visualizers often fail because of their inability to handle problems of a realistic scale. In our research, we have addressed the scalability problem by integrating static and dynamic program information to produce abstract and yet accurate views of complex O-O systems that often provide more useful information than can be obtained by reading the source code. This is the approach we followed in designing Program Explorer, a research prototype for C++ program visualization, which has been used to examine large O-O systems such as Stanford's Interviews library and Taligent's CommonPoint frameworks.
Compact range techniques and measurements (1969)

Compact range techniques for measuring the gain patterns of full-size microwave antennas and for making radar reflectivity measurements are described. The basic principle of this technique is the use of a large collimating device to generate a uniform plane wave across the aperture of a target or antenna without requiring the normal far-field separation. Two different collimating devices were used in the investigation, a paraboloid with a point-source feed and a parabolic cylinder with a line-source feed generated by a large hoghorn. Pattern and gain measurements were made on both compact ranges using a 30-inch paraboloidal test antenna, and the measurements were compared with similar ones made on conventional outdoor ranges. Radar cross-section patterns as a function of aspect angle were measured for various size standard targets and compared with theoretically calculable radar cross-section patterns. The results which have been achieved are very encouraging. They demonstrate that the performance of compact ranges at the <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">X</tex> -band is comparable to that of outdoor ranges.