gebhart/patrepeval huggingface dataset:
An X-band integrated circuit FET oscillator with dielectric resonator stabilization (1983)

Abstract Experimental results are presented for the performance of a MIC common drain GaAs FET oscillator and are compared with the performance of the same oscillator stabilized by using a high Q. temperature compensated dielectric resonator made from barium nonatitanate. The unstabilized oscillator gave 85 mW of Rf power at an efficiency of 20%. whilst the compensated oscillator gave 46 mW of power at an efficiency of 12%. with a line width of only 0.3 MHz as measured at 60 dB below the peak. Over the temperature range 0 to 60°C the frequency of the stabilized oscillator changed only 5 MHz, compared t0 the 30 MHz change found in unstabilized oscillators. Mechanical tuning was easily achieved, and careful choice of coupling between the resonator and oscillator eliminated the hysteresis observed in the mode of oscillation of designs previously reported.
PACE4 Expression in Mouse Basal Keratinocytes Results in Basement Membrane Disruption and Acceleration of Tumor Progression (2005)

Collagen type IV degradation results in disruption and breakdown of the normal basement membrane architecture, a key process in the initiation of tumor microinvasion into the connective tissue. PACE4, a proprotein convertase, activates membrane type matrix metalloproteinases (MT-MMPs) that in turn process collagenase type IV. Because PACE4 is overexpressed in skin carcinomas and in vitro overexpression of PACE4 resulted in enhanced invasiveness, we investigated whether or not in vivo PACE4 expression leads to the acquisition of invasiveness and increased tumorigenesis. Two transgenic mouse lines were designed by targeting PACE4 to the epidermal basal keratinocytes. Transgenic keratinocytes showed increased processing of MT1-MMP and MT2-MMP resulting in collagenase IV activation and collagen type IV degradation. Higher collagenolytic activity partially disrupted normal basement membrane architecture favoring epithelial endophytic growth into the dermis and accelerating invasion and metastasis after chemical carcinogenesis. PACE4 overexpression resulted in enhanced susceptibility to carcinogenesis and tumor progression pointing to a new target for blocking tumor cell invasiveness.
The Use of a Transition Rod May Prevent Proximal Junctional Kyphosis in the Thoracic Spine After Scoliosis Surgery (2011)

Finite element modeling suggests that the pathomechanics at the proximal end of a scoliosis construct may be diminished by preserving the ISL/SSL complex and possibly completely eliminated with the use of rods with a diameter transition at the most proximal level.
Comprehensive Imaging of Ischemic Stroke with Multisection CT (2003)

Computed tomography (CT) is an established tool for the diagnosis of ischemic or hemorrhagic stroke. Nonenhanced CT can help exclude hemorrhage and detect "early signs" of infarction but cannot reliably demonstrate irreversibly damaged brain tissue in the hyperacute stage of ischemic stroke. Further evaluation of patients with ischemic stroke should include differentiation between reversible and irreversible brain damage, which is essential for choosing an appropriate therapy. Perfusion CT provides information about brain perfusion, which permits differentiation of irreversibly damaged brain tissue from reversibly impaired "tissue at risk." CT angiography can help detect stenosis or occlusion of extra- and intracranial arteries. Multisection CT allows the combined use of all three imaging modalities-nonenhanced CT, perfusion CT, and CT angiography-to rapidly obtain comprehensive information regarding the extent of ischemic damage in acute stroke patients. Specific patterns of findings are typically seen in ischemic stroke and can be analyzed more accurately with the combined use of multisection CT and MR imaging. Nevertheless, prospective studies involving a large number of patients will be needed to ascertain the treatment of choice for patients with each of these patterns of findings.
Characterization of a dual-mode horn for submillimeter wavelengths (1983)

A simple dual-mode conical horn has been developed and tested at 0.5 mm, 1.4 mm, 3.1 mm, and 34.2 mm. The horn has nearly equal beam shape in the E and H plane far field patterns with a 3dB half angle of 6°. At 34.2 mm the waveguide reflection loss and the phase center have been determined.
Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein (2019)

Most neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) target the receptor-binding domain (RBD) of the spike glycoprotein and block its binding to the cellular receptor dipeptidyl peptidase 4 (DPP4). The epitopes and mechanisms of mAbs targeting non-RBD regions have not been well characterized yet. Here we report the monoclonal antibody 7D10 that binds to the N-terminal domain (NTD) of the spike glycoprotein and inhibits the cell entry of MERS-CoV with high potency. Structure determination and mutagenesis experiments reveal the epitope and critical residues on the NTD for 7D10 binding and neutralization. Further experiments indicate that the neutralization by 7D10 is not solely dependent on the inhibition of DPP4 binding, but also acts after viral cell attachment, inhibiting the pre-fusion to post-fusion conformational change of the spike. These properties give 7D10 a wide neutralization breadth and help explain its synergistic effects with several RBD-targeting antibodies.
Anomalous Currents in Low Voltage Polymer Tantalum Capacitors (2013)

Low voltage Polymer Ta capacitors fabricated with porous Ta anodes, anodic oxide films of Ta as a dielectric, and poly(3,4-ethylenedioxythiophene) (PEDOT) cathodes were investigated. The polymer cathodes were formed by either pure in-situ polymerization or hybrid polymerization, with in-situ PEDOT inside the porous anodes and a pre-polymerized PEDOT cathode on the external surface of the anodes. Anomalous transient current, DC leakage, and breakdown voltage were observed and investigated at normal and reverse polarities in a broad range of temperatures and voltages. Anomalously high transient current in the ampere range was observed when a pulse of rated voltage at normal polarity (+ on the Ta anode) was applied to the capacitors, and anomalous DC current was observed when rated voltage was applied at low temperature. This effect was significantly more pronounced in the hybrid devices, but significantly decreased in all cases with humidification. The anomalous currents were explained by the presence of dipoles, charged polymer chains, in the conducting polymer cathode at its interface with the dielectric.
Converged broadband optical and wireless communication infrastructure for next-generation telehealth (2010)

Emerging Telehealth and Telemedicine systems need to deliver affordable high-quality health care services by utilizing telecommunication and multimedia technologies in conjunction with medical expertise. In this paper, we propose and demonstrate a telecommunication and networking architecture for implementing next generation Telemedicine and Telehealth systems. Our integrated optical-wireless based network provides super broadband, ultra low-latency connectivity for voice, video, image and data across various telemedicine modalities to facilitate real-time and near real-time communication of remote health care information.
A convenient preparation of 4- and 5-substituted cyclopentenones: a short synthesis of methylenomycin B (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA convenient preparation of 4- and 5-substituted cyclopentenones: a short synthesis of methylenomycin BCarmelo J. Rizzo, Norma K. Dunlap, and Amos B. Smith IIICite this: J. Org. Chem. 1987, 52, 23, 5280–5283Publication Date (Print):November 1, 1987Publication History Published online1 May 2002Published inissue 1 November 1987https://pubs.acs.org/doi/10.1021/jo00232a043https://doi.org/10.1021/jo00232a043research-articleACS PublicationsRequest reuse permissionsArticle Views822Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Phase-shift controlled DC-DC convertorwith bi-directional power flow (2001)

A new zero-voltage switching (ZVS) phase-shift controlled bi-directional DC-DC convertor is proposed. It possesses the conventional features of phase-shifted convertors: constant switching frequency, ZVS and voltage regulation by phase-shift control. However, the convertor has been improved by developing a bi-directional power flow capability and applying synchronous rectification; hence, the on-state voltage drop of the active devices is small. It is therefore recommended for use in electric vehicles. The principle of circuit operation of the proposed convertor is described in detail with mathematical analysis, and experimental results are presented to verify the concept.
Holo-Transferrin and Thrombin Can Interact to Cause Brain Damage (2005)

These results suggest that in addition to hemoglobin-bound iron, Tf-bound iron may contribute to ICH-induced brain injury and that thrombin may contribute to the latter by facilitating cellular iron uptake.
Use of an Allele-Specific Polymerase Chain Reaction Assay to Genotype Pyrethroid Resistant Strains of<i>Boophilus microplus</i>(Acari: Ixodidae) (2001)

A polymerase chain reaction-based assay was developed to detect the presence of a pyrethroid resistance-associated amino acid substitution in Boophilus microplus (Canestrini). The assay uses a simple method for the extraction of genomic DNA from individual larvae and genotypes individuals for the presence of a Phe-->Ile amino acid substitution in the S6 transmembrane segment of domain III of the para-like sodium channel, clearly distinguishing heterozygotes from homozygotes. High frequencies for this amino acid substitution were found in the Corrales and San Felipe strains, which have target site insensitivity mechanisms for pyrethroid resistance. The Caporal resistant strain contained lower yet substantial numbers of amino acid-substituted alleles. Low amino acid substitution frequencies were found in the susceptible reference Gonzales strain and the Coatzacoalcos strain, which has metabolic esterase-mediated pyrethroid resistance. The amino acid substitution was not found in six other strains that were susceptible to pyrethroids.
Inflammatory Bowel Diseases: When Natural Friends Turn into Enemies—The Importance of CpG Motifs of Bacterial DNA in Intestinal Homeostasis and Chronic Intestinal Inflammation (2010)

From numerous studies during the last years it became evident that bacteria and bacterial constituents play a decisive role both in the maintenance of intestinal immune homeostasis as well as in the development and perpetuation of chronic intestinal inflammation. In this review we focus on the role of bacterial DNA which is a potent immunomodulatory component of the bacterial flora. Bacterial DNA has been shown to be protective against experimental colitis. In contrast bacterial DNA essentially contributes to the perpetuation of an already established chronic intestinal inflammation in a Toll-like receptor (TLR)9-dependent manner. This dichotomic action may be explained by a different activation status of essential regulators of TLR signaling like Glycogen synthase kinase 3-β (GSK3-β) depending on the pre-activation status of the intestinal immune system. In this review we suggest that regulators of TLR signaling may be interesting therapeutic targets in IBD aiming at the restoration of intestinal immune homeostasis.
Manipulation of ascending aortic pressure and flow wave reflections with the Valsalva maneuver: relationship to input impedance. (1981)

Dramatic changes in the shape of pulsatile ascending aortic pressure and flow wave forms occur during the Valsalva maneuver in man. To study these changes, aortic pressure and flow signals were recorded in eight patients using a multisensor catheter. Aortic input impedance was derived during the control, strain and postrelease phases of the Valsalva maneuver. During control, well-defined minima and maxima occurred in the spectral plots of impedance moduli. This pattern was accentuated during the postrelease phase. In contrast, input impedance during strain was almost equal to the characteristic impedance for all harmonics. These results imply that during the control and postrelease phases, strong reflections return to the ascending aorta, but during the strain phase, reflections are minimal, absent or more diffuse. From wave transmission theory, it also follows that pulsatile pressure and flow wave forms should be similar in shape in the absence of reflections and dissimilar in the presence of reflections...
Web Services Business Strategies and Architectures (2002)

Adopting Web Services will affect many processes within any organization. To throw light on the most important issues, we have commissioned Experts in the Industry to share their insights. The resulta
Green synthesis, characterization and biological activities of silver nanoparticles from alkalinized <i>Cymbopogon citratus</i> Stapf (2017)

Silver nanoparticles (AgNPs) have been synthesized from the alkalinized leaf extract of Cymbopogon citratus, also known as lemon grass (LG), and characterized for their size and shape using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The total formation of the AgNPs was observed visually with a color change from yellow to brownish-black. Fourier transform infrared spectroscopy (FTIR) and energy dispersive x-ray spectroscopy (EDS/EDX) were conducted to determine the various functional groups and the concentration of metal ions in the nanoparticles. The data analysis showed spherically shaped nanoparticles with a size of 10–33 nm, as revealed by TEM, thereby complementing the result for SEM. FTIR identifies the ethylene group as a reducing and capping agent for the formation of the nanoparticles. The x-ray diffraction pattern confirmed the presence of silver crystallites as well as their size, further confirming the result of the TEM. AgNPs do not exhibit very good potential as free radical scavengers when compared to the standards. The synthesized AgNPs in suspension showed activity against both gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MICs) in the range of 31.25–62.5 µg ml−1. In summary, the synthesized AgNPs possessed an acceptable size and shape.
Semantic Preserving RTL Transformation for Control-Data Slicing in Virtual IPs (2007)

Intellectual Property (IP) reuse has become one of the keys to enabling today's massive System-on-Chip (SoC) designs. However the extensive reuse of IP components has increased the challenge of SoC verification. The higher-level abstraction of IPs allows designers to manage this complexity in today's multi-million gate SoC. Abstraction of complex calculations in data paths greatly simplifies the design for verification. For such an abstraction we first need to separate control from data in IPs. In this paper we have presented an extension to control-data slicing paradigm [4] in which a Register Transfer Level (RTL) transformation of IP models is proposed assisting separation of control state machines from the data processing. Before slicing an IP model into control and data, we first make a transformation which preserves the model semantics. The existing slicing paradigm is enriched by additional analysis and applied to the transformed model which enables the control- data slicing of more general RTL IP models particularly VHDL models with extensive use of local variables.
A Class of near-Perfect Coded Apertures (1978)

Coded aperture imaging of gamma ray sources has long promised an improvement in the sensitivity of various detector systems. The promise has remained largely unfulfilled, however, for either one of two reasons. First, the encoding/decoding method produces artifacts, which even in the absence of quantum noise, restrict the quality of the reconstructed image. This is true of most correlation-type methods. Second, if the decoding procedure is of the deconvolution variety, small terms in the transfer function of the aperture can lead to excessive noise in the reconstructed image. We propose to circumvent both of these problems by use of a uniformly redundant array (URA) as the coded aperture in conjunction with a special correlation decoding method. The correlation of the decoding array with the aperture results in a delta function with deterministically zero sidelobes. The properties of the encoding/decoding method are similar to those of the nonredundant pinhole array (NRA), however, the URA can be composed of thousands of holes whereas the NRA contains less than 40. In short, the URA offers the transmission advantage of the random array or Fresnel zone plate without introducing the artifacts typically seen when those apertures and others are used. It is shown that the reconstructed image in the URA system contains virtually uniform noise regardless of the structure in the original source. Therefore, the improvement over a single pinhole camera will be relatively larger for the brighter points in the source than for the low intensity points.
A fast algorithm on average for all-against-all sequence matching (2003)

We present an algorithm which attempts to align pairs of subsequences from a database of genetic sequences. The algorithm simulates the classical dynamic programming alignment algorithm over a suffix array of the database. We provide a detailed average case analysis which shows that the running time of the algorithm is subquadratic with respect to the database size. A similar algorithm solves the approximate string matching problem in sublinear average time.
A Software System Development Life Cycle Model for Improved Stakeholders’ Communication and Collaboration (2010)

<p>Software vendors and entrepreneurs, who try to introduce an innovative software product to a specific organization or an entire market, enter a long and tedious process. During this process, the market and various organizations evaluate the product from different perspectives, such as software robustness, manufacturer reliability, and corporate need for the product. The vendors and entrepreneurs engaged in this process encounter decision crossroads for which no relevant guidance exists in the literature.<br /> The research closely monitored the processes associated with the introduction and assimilation of an innovative off-the-shelf (OTS) software product into five different organizations in different vertical market segments. Observations were carried out to assess organizational and marketing processes and to document and analyze what the software product undergoes before it is accepted for acquisition or full implementation within the organization.<br /> The research outcomes offer a unified, collaborative multi-tier System Development Life Cycle (SDLC) framework and methodology for packaged OTS software products that greatly improves communication and collaboration among the stakeholders. Each tier addresses a different force or stakeholder involved in the software market: vendor, customer, consultants and integrators. All stakeholders refer to the same time-line thus; tasks of various stakeholders are streamlined. Adherence to the unified time-line brings about an increased amount of stakeholder interaction, communication and collaboration.<br /> Newly found tasks that improve communication and collaboration among stakeholders include (1) offering of the OTS software product together with personnel as a bundle, (2) an improvisation-intensive iterative task of weaving potential customers’ requirements into the prototype, and (3) a third sale milestone, representing the successful diffusion of the product. The significance of this interdisciplinary research stems from its unique position at a crossroad between software engineering, marketing, and business administration, which has not yet been sufficiently explored or cultivated.</p>
Photocatalytic decomposition of water and acetic acid using a powder-layer photoelectrochemical structure (1985)

Nonmetallized TiO/sub 2/ powder incorporated into a thin (a few microns), porous, layer above a metallized substrate has been used to photosensitize the decompositions of water and acetic acid in an aqueous gas-phase environment. Quantum efficiencies 0.35% and 11%, respectively, show that this structure has a catalytic activity comparable to dispersions of partially metallized powders. Decomposition products in the case of acetic acid support the photoelectrochemical mechanism used to described the activity of the powder-layer structure. Evidence is given for the involvement of water in the photoreactions of acetic acid.
Point and wedge tungsten-on-silicon field emitter arrays (2002)

The authors have measured 20 mu A/tip from single-tip silicon field emitter array (FEA) cells made from 10/sup 15//cm/sup 3/ n-type silicon. The current-voltage characteristics show a linear Fowler-Nordheim relationship and do not show current saturation. These results indicate that silicon-based FEAs might be able to compete with metal-based FEAs for RF power applications. In addition, the authors report the fabrication of silicon-based wedge, trench, and tungsten-on-silicon FEA structures. These new structures might have advantages and disadvantages compared with the classical point-like structures in some applications such as linear beam tubes.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Reconsidering intercultural (communication) competence in the workplace: a dialectical approach (2015)

Scholars and practitioners from a variety of disciplinary backgrounds (sociolinguistics, language education, communication, business, etc.) have investigated and promoted the notion of competence in intercultural interaction for many years. They have addressed complex issues and proposed culture general and culture specific models and applied these models in various contexts including workplace interaction. In this paper, we examine the assumptions about the cultural identities of workers in contemporary research and training in intercultural competence. These assumptions seem to reinscribe the colonialist traveler/cosmopolitan – focusing on individual characteristics, motivation, and skill sets, often through a Eurocentric lens. A dialectical perspective foregrounds individual characteristics of competence with larger societal attitudes and laws that impact the treatment of women, gays, and others. A dialectical perspective can help us better understand the opportunities and constraints facing different people in workplaces around the world. By complicating our understanding of competence and taking a dialectical perspective, we hope to advance theory and practice in this important topic area.