gebhart/patrepeval huggingface dataset:
Sharkskin mechanism of high‐impact polystyrene (HIPS) and rheological behavior of HIPS/TiO<sub>2</sub> composites (2005)

Abstract The rheological behaviors of high‐impact polystyrene (HIPS) and HIPS/TiO 2 composites were investigated by use of a rheometer in the present article. HIPS exhibited a constant critical stress of the sharkskin in various temperatures, and the analysis indicated that the mechanism of sharkskin of HIPS was wall–slip and its special temperature dependency was determined by weak wall–melt adsorption. The experimental results also showed that the introduction of TiO 2 into HIPS only slightly influenced the apparent viscosity (η a ) of the composites. Moreover, TiO 2 exhibited an unusual effect on the non‐Newtonian index of the composites at high shear rate. Both phenomena indicated the increase of inner free volume induced by TiO 2 in molecularly rigid HIPS. Moreover, it was noteworthy that a featured stress could be used to label the dispersion of TiO 2 in the HIPS matrix, and the numeric affinity of this featured stress and the critical stress of sharkskin revealed that both processes were relevant to the same molecular relaxation. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 96: 802–807, 2005
The signature of scrapie: differences in the PrP genotype profile of scrapie–affected and scrapie-free UK sheep flocks (2000)

The amino-acid sequence of the PrP protein plays an important role in determining whether sheep are susceptible to scrapie. Although the genetics of scrapie susceptibility are now well understood, there have been few studies of the PrP gene at the population level, especially in commercially farmed sheep. Here we describe the PrP genetic profiles of the breeding stock of four UK sheep flocks, comprising nearly 650 animals in total. Two flocks had been scrapie affected for about eight years and two were scrapie free. Scrapie-resistant PrP genotypes predominated in all flocks but highly susceptible genotypes were present in each case. The distribution of PrP genotypes was similar in the scrapie-affected and scrapie-free flocks. The former, however, showed a slight but significant skew towards more susceptible genotypes despite their previous losses of susceptible sheep. Surprisingly, this skew was apparent in younger, but not older, sheep. We suggest that these patterns may occur if sheep flocks destined to become scrapie affected are predisposed by a genetic profile skewed towards susceptibility. The age structure of the scrapie-affected flocks suggests that the number of losses attributable directly or indirectly to scrapie considerably exceeds that recognized by the farmers, and also that significant losses may occur even in sheep of a moderately susceptible genotype. Similar patterns were not detected in the scrapie-free flocks, indicating that these losses are associated with scrapie infection as well as genotype.
Solubility behavior of .beta.-cyclodextrin in water/cosolvent mixtures (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolubility behavior of .beta.-cyclodextrin in water/cosolvent mixturesAlexis K. Chatjigakis, Cecile Donze, Anthony W. Coleman, and Philippe CardotCite this: Anal. Chem. 1992, 64, 14, 1632–1634Publication Date (Print):July 15, 1992Publication History Published online1 May 2002Published inissue 15 July 1992https://pubs.acs.org/doi/10.1021/ac00038a022https://doi.org/10.1021/ac00038a022research-articleACS PublicationsRequest reuse permissionsArticle Views7116Altmetric-Citations121LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparative analysis of skin sensitization potency of acrylates (methyl acrylate, ethyl acrylate, butyl acrylate, and ethylhexyl acrylate) using the local lymph node assay (2007)

There are currently available no systematic experimental data on the skin sensitizing properties of acrylates that are of relevance in occupational settings. Limited information from previous guinea-pig tests or from the local lymph node assay (LLNA) is available; however, these data are incomplete and somewhat contradictory. For those reasons, we have examined in the LLNA 4 acrylates: butyl acrylate (BA), ethyl acrylate (EA), methyl acrylate (MA), and ethylhexyl acrylate (EHA). The LLNA data indicated that all 4 compounds have some potential to cause skin sensitization. In addition, the relative potencies of these acrylates were measured by derivation from LLNA dose-response analyses of EC3 values (the effective concentration of chemical required to induce a threefold increase in proliferation of draining lymph node cells compared with control values). On the basis of 1 scheme for the categorization of skin sensitization potency, BA, EA, and MA were each classified as weak sensitizers. Using the same scheme, EHA was considered a moderate sensitizer. However, it must be emphasized that the EC3 value for this chemical of 9.7% is on the borderline between moderate (<10%) and weak (>10%) categories. Thus, the judicious view is that all 4 chemicals possess relatively weak skin sensitizing potential.
Novel series of six-coordinated iron(II) diimine complexes with half-quenched spin (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel series of six-coordinated iron(II) diimine complexes with half-quenched spinE. Koenig and K. MadejaCite this: Inorg. Chem. 1968, 7, 9, 1848–1855Publication Date (Print):September 1, 1968Publication History Published online1 May 2002Published inissue 1 September 1968https://pubs.acs.org/doi/10.1021/ic50067a030https://doi.org/10.1021/ic50067a030research-articleACS PublicationsRequest reuse permissionsArticle Views256Altmetric-Citations64LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Bootstrap: a fast blind adaptive signal separator (1992)

A fast multidimensional adaptive algorithm, Bootstrap, is proposed for multiple signal separation. It separates multiple uncorrelated signals imposed on each other. The bootstrap adaptive algorithm, which does not require training sequences, uses an optimization criteria that is based on minimization of output signal correlations. The learning process of this algorithm is compared with that of the least mean square (LMS) algorithm for different eigenvalue spreads. It has been found from computer simulations that the Bootstrap algorithm converges much faster than the LMS algorithm. The learning process of the Bootstrap algorithm is almost independent of eigenvalue spread.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Attention Branch Network: Learning of Attention Mechanism for Visual Explanation (2019)

Visual explanation enables humans to understand the decision making of deep convolutional neural network (CNN), but it is insufficient to contribute to improving CNN performance. In this paper, we focus on the attention map for visual explanation, which represents a high response value as the attention location in image recognition. This attention region significantly improves the performance of CNN by introducing an attention mechanism that focuses on a specific region in an image. In this work, we propose Attention Branch Network (ABN), which extends a response-based visual explanation model by introducing a branch structure with an attention mechanism. ABN can be applicable to several image recognition tasks by introducing a branch for the attention mechanism and is trainable for visual explanation and image recognition in an end-to-end manner. We evaluate ABN on several image recognition tasks such as image classification, fine-grained recognition, and multiple facial attribute recognition. Experimental results indicate that ABN outperforms the baseline models on these image recognition tasks while generating an attention map for visual explanation. Our code is available.
<title>Watermarking spot colors</title> (2003)

Watermarking of printed materials has usually focused on process inks of cyan, magenta, yellow and black (CMYK). In packaging, almost three out of four printed materials include spot colors. Spot colors are special premixed inks, which can be produced in a vibrant range of colors, often outside the CMYK color gamut. In embedding a watermark into printed material, a common approach is to modify the luminance value of each pixel in the image. In the case of process color work pieces, the luminance change can be scaled to the C, M, Y and K channels using a weighting function, to produce the desired change in luminance. In the case of spot color art designs, there is only one channel available and the luminance change is applied to this channel. In this paper we develop a weighting function to embed the watermark signal across the range of different spot colors. This weighting function normalizes visibility effect and signal robustness across a wide range of different spot colors. It normalizes the signal robustness level over the range of an individual spot color’s intensity levels. Further, it takes into account the sensitivity of the capturing device to the different spot colors.
Parenteral Lipid Emulsions in Guinea Pigs Differentially Influence Plasma and Tissue Levels of Fatty Acids, Squalene, Cholesterol, and Phytosterols (2014)

Abstract Lipid emulsions are made by mixing vegetable and/or fish oils with egg yolk and contain different types and amounts of fatty acids and sterols. This study assessed the effects of oral diet, soybean oil (SO)‐, fish oil (FO)‐, a mixture of olive and soybean oil (OOSO)‐, and a mixture of fish, olive, coconut, and soybean oil (FOCS)‐based emulsions on plasma triacylglycerols and plasma and tissue fatty acid and sterol content following acute and chronic intravenous administration in the guinea pig. Upon acute administration, peak triacylglycerols were highest with SO and lowest with OOSO. Upon chronic administration, the plasma triglyceride levels did not increase in any group over that of the controls. Fatty acid levels varied greatly between organs of animals on the control diets and organs of animals following acute or chronic lipid administration. Squalene levels increased in plasma following acute administration of OOSO, but plasma squalene levels were similar to control in all emulsion groups following chronic administration. Total plasma phytosterol levels were increased in the SO, OOSO, and FOCS groups following both acute and chronic infusions, whereas phytosterols were not increased following FO infusion. Total phytosterol levels were higher in liver, lung, kidney and adipose tissue following SO and OOSO. Levels were not increased in tissues after FO and FOCS infusion. These results indicate that fatty acid and sterol contents vary greatly among organs and that no one tissue reflects the fatty acid or sterol composition of other tissues, suggesting that different organs regulate these compounds differently.
Fraudulent Transaction Detection in Credit Card by Applying Ensemble Machine Learning techniques (2019)

In the present day scenario, fraudulent activities associated with financial transactions, particularly while using credit card, are observed to be occurring in a fast rate. Hence, a fraud detection system involving various detection techniques is very much essential for the financial institutions to sustain the goodwill from the customers. Several fraud detection techniques have been proposed by researchers as well as practitioners with application of various algorithms to find the pattern of fraud. In this study, the application of various classification models are proposed by implementing machine learning techniques to find out the accuracy and other performance parameters to identify the fraudulent transaction. Classification algorithms such as K-Nearest Neighbor (K-NN), Extreme Learning Machine (ELM), Random Forest (RF), Multilayer Perceptron (MLP) and Bagging classifier have been implemented to critically assessed their performances and the performances are evaluated. We have proposed a predictive classification model by ensemble of five individual algorithms, as it provides a better predictive performance.
Targeting of interleukin-2 to the periplasm of Escherichia coli (1993)

A synthetic gene coding for interleukin-2 (IL-2) was used to produce large amounts of recombinant IL-2 (met-IL-2) in Escherichia coli. Met-IL-2 was found to accumulate in the cytoplasm in an insoluble, aggregated form. Inclusion bodies located at the pole caps of cells were detected using immunogold labelling. Constructs were designed to fuse the IL-2 gene to DNA fragments encoding signal peptides for an outer-membrane protein (OmpA) or for a periplasmic protein (PhoA) of E. coli. No significant maturation was observed with these fusion proteins which were found in an insoluble form in the cytoplasm. The influence of charge disposition at the N-terminus of the mature portion of the protein was investigated by replacing positively charged amino acids with glutamic acid. None of the introduced substitutions had any effect. Various factors that might affect expression, secretion and folding were examined in an attempt to obtain secretion. By fusing IL-2 to the precursor maltose-binding protein (preMBP) a large fraction of the preMBP-IL-2 protein was correctly processed and transported to the periplasmic space. IL-2 derived from MBP-IL-2 after FXa cleavage possessed similar specific activity to recombinant IL-2 produced in Chinese Hamster ovary cells.
Dental Pulp Tissue Engineering in Full-length Human Root Canals (2013)

The clinical translation of stem-cell-based dental pulp regeneration will require the use of injectable scaffolds. Here, we tested the hypothesis that stem cells from exfoliated deciduous teeth (SHED) can generate a functional dental pulp when injected into full-length root canals. SHED survived and began to express putative markers of odontoblastic differentiation after 7 days when mixed with Puramatrix™ (peptide hydrogel), or after 14 days when mixed with recombinant human Collagen (rhCollagen) type I, and injected into the root canals of human premolars in vitro. Roots of human premolars injected with scaffolds (Puramatrix™ or rhCollagen) containing SHED were implanted subcutaneously into immunodeficient mice (CB-17 SCID). We observed pulp-like tissues with odontoblasts capable of generating new tubular dentin throughout the root canals. Notably, the pulp tissue engineered with SHED injected with either Puramatrix™ or rhCollagen type I presented similar cellularity and vascularization when compared with control human dental pulps. Analysis of these data, collectively, demonstrates that SHED injected into full-length human root canals differentiate into functional odontoblasts, and suggests that such a strategy might facilitate the completion of root formation in necrotic immature permanent teeth.
I/sub DDQ/ testing and defect classes-a tutorial (2002)

I/sub DDQ/ testing of CMOS ICs is a technique for production quality and reliability improvement, design validation, and failure analysis. The origin and basic concepts of I/sub DDQ/ testing are reviewed. The relationship of I/sub DDQ/ testing to other test methods is considered in the context of the whole IC life cycle from design, fabrication, and test through end use. A comprehensive test strategy is described that uses defect classes based on defect electrical properties rather than traditional fault models.
Pharmacokinetics and Haemostatic Status During Consecutive Infusions of Recom binant Tissue-Type Plasminogen Activator in Patients with Acute Myocardial Infarction (1989)

Pharmacokinetics and systemic effects of recombinant tissue-type plasminogen activator (rt-PA) were determined during coronary thrombolysis in 12 acute myocardial infarction patients using a consecutive intravenous infusion regimen. Ten mg rt-PA were infused in 2 minutes resulting in a peak plasma concentration (mean +/- SD) of 3310 +/- 950 ng/ml, followed by 50 mg in 1 h and 30 mg in 1.5 h yielding steady state plasma levels of 2210 +/- 470 ng/ml and 930 +/- 200 ng/ml, respectively. All patients received intravenous heparin. Total clearance of rt-PA was 380 +/- 74 ml/min, t1/2 alpha was 3.6 +/- 0.9 min and t1/2 beta was 16 +/- 5.4 min. After 90 min, in plasma samples containing anti-rt-PA-IgG to inhibit in vitro effects, fibrinogen was decreased to 54%, plasminogen to 52%, alpha 2-antiplasmin to 25%, alpha 2-macroglobulin to 90% and antithrombin III to 85% of initial values. Coagulation times were prolonged and fibrin D-dimer concentrations increased from 0.40 to 2.7 micrograms/ml. It is concluded that pharmacokinetics of rt-PA show low interpatient variability and that its short mean residence time in plasma allows precise control of therapy. Apart from its moderate effect on the haemostatic system, rt-PA appears to lyse a fibrin pool in addition to the coronary thrombus.
Domain-structure analysis of recombinant rat hormone-sensitive lipase (1996)

Hormone-sensitive lipase (HSL) plays a key role in lipid metabolism and overall energy homoeostasis, by controlling the release of fatty acids from stored triglycerides in adipose tissue. Lipases and esterases form a protein superfamily with a common structural fold, called the alpha/beta-hydrolase fold, and a catalytic triad of serine, aspartic or glutamic acid and histidine. Previous alignments between HSL and lipase 2 of Moraxella TA144 have been extended to cover a much larger part of the HSL sequence. From these extended alignments, possible sites for the catalytic triad and alpha/beta-hydrolase fold are suggested. Furthermore, it is proposed that HSL contains a structural domain with catalytic capacity and a regulatory module attached, as well as a structural N-terminal domain unique to this enzyme. In order to test the proposed domain structure, rat HSL was overexpressed and purified to homogeneity using a baculovirus/insect-cell expression system. The purification, resulting in > 99% purity, involved detergent solubilization followed by anion-exchange chromatography and hydrophobic-interaction chromatography. The purified recombinant enzyme was identical to rat adipose-tissue HSL with regard to specific activity, substrate specificity and ability to serve as a substrate for cAMP-dependent protein kinase. The recombinant HSL was subjected to denaturation by guanidine hydrochloride and limited proteolysis. These treatments resulted in more extensive loss of activity against phospholipid-stabilized lipid substrates than against water-soluble substrates, suggesting that the hydrolytic activity can be separated from recognition of lipid substrates. These data support the concept that HSL has at least two major domains.
Foundations programs: Models that work (2012)

<p>Programs that introduce academic staff to learning and teaching in Higher Education are now well established in many countries. In Australia they are becoming more systematised to respond to the professionalism of university learning and teaching and a growing regard to quality assurance. This paper outlines a project where a range of typical models of Foundations programs were described and, with the assistance of a stakeholder group, the characteristics of the models that promoted effectiveness and efficiency were identified. This work was a sub-project of the Australian Learning and Teaching Council grant, Preparing Academics to Teach in Higher Education (PATHE).</p><p>In the initial phase, existing data about Australian Foundation programs was analysed to identify characteristics that could be used in describing different models. The second phase employed a multi-stage methodology: identification of successful Foundation programs that represented elements of the model; writing case studies of good practice and; consideration of the characteristics of effective programs by a stakeholder group (senior management, senior and early career academics, academic developers and students).</p><p>A visual representation identifying key elements of different models was developed: philosophical approach underpinned the intersecting areas of curriculum (content and activities), mode of delivery (face-to-face, on-line, intensive or stretched and policy requirements).</p><p>Using these elements and through conducting interviews, five good practice case studies were written to describe the range of practice in the Australian HE sector. A clear picture emerged of how institutional philosophy and context influenced the structure, content and delivery patterns of programs. Additionally, the predominance of mandatory programs reflected a growing emphasis on the importance of quality teaching. The cases also demonstrated how the four key themes of successful programs, as identified by the stakeholder group, could be translated into practice. These themes were: Embedding a student centred approach; Encouraging a scholarly approach to teaching; Building networks and relationships and; Orienting staff to their institutional context. A noteworthy observation in terms of effectiveness and efficiency was that of flexibility.</p><p>The five case studies give insight into the range of Foundation programs across Australia, allow sharing of practice and, provide models for benchmarking purposes. Recognising that these programs have multiple purposes, the insights gained from the stakeholder group, have provided four thematic touchstones for the design and evaluation of Foundation programs. The benefits of allowing for reflection, building of learning communities amongst the participants and, providing opportunities for negotiation and content to take into account individual contexts and experience were clearly identified. Importantly, it was noted that there was a strong connection between completion of Foundation programs and personal and institutional success in learning and teaching.</p>