gebhart/patrepeval huggingface dataset:
Tendon actuated cellular mechanisms for morphing aircraft wing (2007)

Morphing aircraft wings offer great potential benefits of achieving multi mission capability as well as high maneuverability under different flight conditions. However, they present many design challenges in the form of conflicting design requirements. The current research aims to develop design methodologies for the design of a morphing aircraft wing. Focus of this work is on developing an internal mechanism of the wing that can produce the desired wing shape change. This paper presents a design methodology that employs planar unit cells of pre-determined shape and layout as the internal wing structure for achieving the desired wing shape change. This method is particularly useful in cases where the desired morphing is two-dimensional in nature. In such cases, intuitive cell designs such as diamond or hexagonal shaped cells may be used in layouts that achieve desired wing morphing. The shape change depends on the cell shape as well as cell arrangement in the design domain. In this paper, a design based on the TSCh wing (NextGen Aeronautics Inc.) using cellular mechanisms to achieve a two-dimensional wing shape change is discussed. Additionally, a reeling mechanism for achieving cable actuation is presented
Vapor Deposition of Fluoropolymer Surfaces (2014)

Chemical vapor deposition (CVD) polymerization methods result in a versatile platform for the fabrication of high quality fluoropolymer films. This chapter provides an insight into the mechanism of formation of these films, the ability to tailor their properties by tuning the experimental conditions and the chemistry associated with the multiple functionalities available. It describes the examples of iCVD fluoropolymer reactants such as polytetrafluoroethylene (PTFE), Polyvinylidene fluoride (PVDF), poly(1H,1H,2H,2H-perfluorodecyl acrylate p(PFDA) and its copolymers and example process conditions. The chapter summarizes various subtypes of CVD polymerization processes. The scale-up of CVD methods and the possibility to integrate them with vacuum processes currently used in the manufacturing industry permit to benefit from all the advantages of the fluorinated films in their commercialization. Continuous investigation in these materials has led to new applications in many different fields, such as optoelectronic, biomedicine or membrane separation systems, making a big impact in polymer thin-film technology.
Fluorescence excitation spectrum of organic compounds in solution. Part 1.—Systems with quantum yield independent of the exciting wavelength (1958)

G. Weber and F. W. J. Teale, Trans. Faraday Soc., 1958, 54, 640 DOI: 10.1039/TF9585400640
Voltage‐dependent calcium currents are enhanced in dorsal root ganglion neurones from the Bio Bred/Worchester diabetic rat. (1995)

1. Whole-cell, high-threshold, voltage-dependent calcium currents (ICa) were enhanced in acutely dissociated, capsaicin-sensitive dorsal root ganglion neurones from diabetic Bio Bred/Worchester (BB/W) rats, compared with those from age-matched, non-diabetic controls. The magnitude of the enhancement increased with the duration of diabetes, and reached significance at diabetic durations of 6 months (diabetic: 6.3 +/- 0.4 nA; current density (CD), 157 +/- 12 pA pF-1; means +/- S.E.M., n = 9, P < 0.01; control: 3.9 +/- 0.6 nA; CD, 116 +/- 11 pA pF-1; n = 18) and 8 months (diabetic: 7.6 +/- 0.4 nA; CD, 177 +/- 25 pA pF-1; n = 11, P < 0.005; control: 5.1 +/- 0.5 nA; CD, 111 +/- 26 pA pF-1; n = 15). Low-threshold, voltage-dependent ICa were also enhanced in neurones from animals diabetic for 8 months (diabetic: 2.5 +/- 0.7 nA, n = 4, P < 0.05; control: 0.7 +/- 0.5 nA, n = 6). 2. The ICa enhancement was prevented by long-term treatment of diabetic animals with an aldose reductase inhibitor (ARI; peak ICa at 6 months: 4.41 +/- 0.48 nA, n = 2; at 8 months: 4.32 +/- 0.60 nA, n = 9). 3. The ICa enhancement was not due to a shift in the voltage dependence of either the current-voltage relationship or steady-state inactivation. 4. The L channel antagonist nifedipine and preferential N channel antagonist omega-conotoxin GVIA (omega-CgTX) caused a greater inhibition of high-threshold ICa in diabetic neurones compared with controls (nifedipine: control: 25 +/- 3%, n = 26; diabetic: 36 +/- 7%, n = 11; omega-CgTX: control: 40 +/- 4%, n = 21; diabetic: 50 +/- 7%, n = 7). Diabetic neurones also demonstrated a significantly greater residual current (2.44 +/- 0.34 nA, n = 7) in the presence of both antagonists vs. controls (1.28 +/- 0.30 nA, n = 8, P < 0.05), suggesting that N-, L- and additional non-N-, non-L-type high-threshold ICa were enhanced.
Infection of Turnip Leaf Protoplasts with Turnip Rosette Virus (1979)

SUMMARY The optimum conditions for infection of turnip protoplasts with turnip rosette virus (TRosV) were 0.2 to 2 × 105 protoplasts/ml, 5 to 10 µg virus/ml, 1 µg poly-l-ornithine/ml in 0.6 m-mannitol, buffered with 5 to 10 mm-tris at pH 7.0 to 8.6. Under these conditions, 70% of protoplasts became infected, as indicated by staining with fluorescent antibody. The proportion of protoplasts infected was determined by factors such as pH and buffer ions and by the concentrations of protoplasts, virus and poly-l-ornithine during inoculation. The period of pre-inoculation incubation of virus and poly-l-ornithine was also critical, but mannitol concentration and the inoculation period and temperature had little effect on percentage protoplasts infected. Time course studies showed a single step multiplication of TRosV; the virus was detected on sucrose gradients at 24 h after inoculation and at 60 h reached its maximum concentration, 3 × 106 virions per infected protoplast.
An Automated Tilting Bed for Continuous Control of Blood Pressure (1974)

An automative system for continuous maintainence of arterial pressure within set bounds by means of a bed programmed to tilt head up or down in response to fluctuations in arterial pressure has been designed. Pressure is measured continuously with an indwelling arterial pressure transducer. The system hastened return of blood pressure to normotensive levels in 15 dogs made hypertensive with metaraminol or hypotensive with trimethaphan camphorsulfonate.
MAC layer support for group communication in wireless sensor networks (2005)

In this paper, we investigate the problem of providing efficient communication primitives across domains of wireless sensor network (WSN) applications. We argue both qualitatively and quantitatively that group communication among sensors of geographic proximity is one of the basic building blocks of many WSN applications. Furthermore, group communication awareness needs to be embedded and implemented at the MAC layer due to the broadcast nature of wireless medium. We devise a MAC protocol, called LGC-MAC to enable efficient single-hop one-to-many and many-to-one communication. We present case studies of two example applications, acoustic target tracking and propagation of information with feedback using LGC-MAC and demonstrate that LGC-MAC can improve the response time, alleviate channel contention and provide better fault tolerance to packet collisions and wireless errors.
HIF-1α controls extracellular matrix synthesis by epiphyseal chondrocytes (2003)

The transcription factor HIF-1alpha plays a crucial role in modifying gene expression during low oxygen tension. In a previous study, we demonstrated that HIF-1alpha is essential for chondrocyte growth arrest and survival in vivo. To explore further the role of HIF-1alpha in cartilage biology, we undertook studies with primary epiphyseal chondrocytes with a targeted deletion of HIF-1alpha. In this study, we show that HIF-1alpha is necessary for regulating glycolysis under aerobic and anaerobic conditions. HIF-1alpha-null chondrocytes were unable to maintain ATP levels in hypoxic microenvironments, indicating a fundamental requirement for this factor for the regulation of chondrocyte metabolism. Synthesis of the angiogenic factor vascular endothelial growth factor was also significantly induced by hypoxia, and this increase is lost in HIF-1alpha-null mutant cells. Under hypoxic conditions, aggrecan mRNA and protein levels were significantly reduced in chondrocytes lacking the HIF-1alpha transcription factor. Interestingly, strongly increased type-II collagen protein levels were detected in wild-type cells after 44 hours of hypoxia. In addition, type-II collagen mRNA and protein levels were strongly decreased under low oxygen in chondrocytes lacking HIF-1alpha. In summary, our results clearly demonstrate the importance of HIF-1alpha in maintenance of anaerobic glycolysis, and thereby extracellular matrix synthesis, of epiphyseal chondrocytes.
The Synthesis of Tenuazonic and Congeneric Tetramic Acids (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of Tenuazonic and Congeneric Tetramic AcidsStanton A. Harris, Linda V. Fisher, and Karl FolkersCite this: J. Med. Chem. 1965, 8, 4, 478–482Publication Date (Print):July 1, 1965Publication History Published online1 May 2002Published inissue 1 July 1965https://pubs.acs.org/doi/10.1021/jm00328a014https://doi.org/10.1021/jm00328a014research-articleACS PublicationsRequest reuse permissionsArticle Views431Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Controlling the primary mode of gyroscopes with a phase-based amplitude regulation (2011)

This paper presents the circuit implementation of an amplitude regulation for the primary mode of gyroscopes based on phase-shifting. Instead of regulating the AC or DC value of the driving stage in order to maintain a constant primary oscillation, this concept introduces a tunable phase delay into the driving loop. The high voltages of the driving stage can be set to a constant value and do not have to be adjusted. The driving stage can be realized with a set of simple switches applying two fixed voltages to the gyroscope for actuation. This reduces the complexity of the circuitry enormously. Measurements reveal that the frequency is held constant with a sigma of 1Hz and the amplitude regulation is within 0.6% of the defined value.
Radioimmunoimaging of human lymphomas with I-131 tumor-specific monoclonal antibody (1984)

All these data provide a strong rationale for clinical evaluation of PF4942847 alone or in combination with zoledronic acid in osteosarcoma. Clin Cancer Res; 22(10); 2520-33. ©2015 AACR.
Triple layer refractive index profile for tapered fibre beam expanders (1989)

In the letter a three-layer index profile for a tapered fibre beam expander is presented. It is shown that both the size and ellipticity of the modal field can be changed simultaneously by using a proper index profile.
Variable selection for ad prediction (2008)

We consider the problem of predicting the probability of a click for an advertisement when the outcome of a click or no-click is expressed by means of a set of a large number of variables. Many, if not most, of these variables are very weakly related to the clicking of the ad. Thus, a traditional approach to address this problem that treats each variable on an equal and blind footing takes away the interpretability in explaining the underlying process of the outcome. Such an approach would be computationally expensive and, further, may suffer from poor generalization.
Effect of Polymer Architecture of Amphiphilic Poly(2‐oxazoline) Copolymers on the Aggregation and Aggregate Structure (2007)

Abstract The micelle formation of five poly(2‐oxazoline) diblock, triblock and gradient copolymers in water was investigated using fluorescence correlation spectroscopy. The polymers were synthesized by consecutive or simultaneous living cationic polymerization of 2‐methyl‐2‐oxazoline for the hydrophilic and 2‐nonyl‐2‐oxazoline for the hydrophobic polymer segments. Fractions of the polymers were fluorescence‐labeled at the polymer termini with TRITC for the FCS measurements. The hydrodynamic radii of solubilized polymer unimers and of the aggregates (micelles) were determined in a concentration range of 10 −8 –10 −3 M and were found to depend in a characteristic way on the polymer architecture. magnified image
Phase-field model of eutectic growth (1994)

A phase-field model which describes the solidification of a binary eutectic alloy with a simple symmetric phase diagram is introduced and the sharp-interface limit of this model is explored both analytically and numerically.
The next geriatric generation. (2007)

Baby boomers are just beginning their advance on the nation's health care system and, unless hospitals act quickly, the health care system will be unprepared for a cascade of complex patient needs.
Differentiation of pluripotent stem cells into endothelial cells (2015)

Progress in differentiating endothelial cells from ESC and iPSC has been made. The recent report of formation of endothelial colony forming cells from human ESC and iPSC provides a protocol that can generate clinically relevant numbers of cells for human cell therapy.
Modulation of L-type Calcium Channel Expression during Retinoic Acid-induced Differentiation of H9C2 Cardiac Cells (1999)

The molecular mechanisms underlying the developmental regulation of L-type voltage-dependent Ca(2+) channels (VDCCs) are still unknown. In this study, we have characterized the expression patterns of skeletal (alpha(1S)) and cardiac (alpha(1C)) L-type VDCCs during cardiogenic differentiation in H9C2 cells that derived from embryonic rat heart. We report that chronic treatment of H9C2 cells with 10 nM all-trans-retinoic acid (all-trans-RA) enhanced cardiac Ca(2+) channel expression, as demonstrated by reverse transcription-polymerase chain reaction, immunoblotting, and indirect immunofluorescence studies, as well as patch-clamp experiments. In addition, RA treatment prevented expression of functional skeletal L-type VDCCs, which were restricted to myotubes that spontaneously appear in control H9C2 cultures undergoing myogenic transdifferentiation. The use of specific skeletal and cardiac markers indicated that RA, by preventing myogenic transdifferentiation, preserves cardiac differentiation of this cell line. Altogether, we provide evidence that cardiac and skeletal subtype-specific L-type Ca(2+) channels are relevant functional markers of differentiated cardiac and skeletal myocytes, respectively. In conclusion, our data demonstrate that in vitro RA stimulates cardiac (alpha(1C)) L-type Ca(2+) channel expression, therefore supporting the hypothesis that the RA pathway might be involved in the tissue specific expression of Ca(2+) channels in mature cardiac cells.
One-pot synthesis of 4-methylisoquinolines via a sequential Pd-catalyzed Heck reaction and intramolecular cyclization (2013)

An efficient, one-pot synthesis of 4-methylisoquinolines via a cascade Pd-catalyzed Heck reaction, intramolecular cyclization and isomerization has been developed. This reaction has a wide range of substrates with various functional groups, and the corresponding products have been obtained in good yields.
Walking of a Planar Biped with an Intuitive Method (2009)

This work deals with an intuitive method for a planar biped to walk, which is named Relative Trajectory Control (RTC) method. A key feature of the proposed RTC method is that feet of the robot are controlled to track a given trajectory, which is specially designed relative to the base body of the robot. The trajectory of feet is presumed from analysis of the walking motion of a human being. A simple method to maintain a stable posture while the robot is walking is also introduced in RTC method. In this work, the biped is modeled as a free-floating robot, of which dynamic model is obtained in the Cartesian space. Using the obtained dynamic model, the robot is controlled by a model-based feedback control scheme. The author shows a preliminary experimental result to verify that the biped robot with RTC method can walk on the even or uneven surfaces.
Effect of ligand and solvent deuteration on the excited state properties of the tris(2,2'-bipyridyl)ruthenium(II) ion in aqueous solution. Evidence for electron transfer to solvent (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of ligand and solvent deuteration on the excited state properties of the tris(2,2'-bipyridyl)ruthenium(II) ion in aqueous solution. Evidence for electron transfer to solventJ. Van Houten and Richard J. WattsCite this: J. Am. Chem. Soc. 1975, 97, 13, 3843–3844Publication Date (Print):June 1, 1975Publication History Published online1 May 2002Published inissue 1 June 1975https://pubs.acs.org/doi/10.1021/ja00846a062https://doi.org/10.1021/ja00846a062research-articleACS PublicationsRequest reuse permissionsArticle Views717Altmetric-Citations129LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Clinical Usefulness of Imaging Performed After CT Angiography That Was Negative for Pulmonary Embolus in a High-Risk Oncologic Population (2002)

Negative results of CT angiography for pulmonary embolism did not deter referring physicians from ordering other confirmatory imaging tests in 21% of patients in a high-risk oncologic population. Those additional tests rarely revealed results that might have been clinically important.
Improved predictive models for acute kidney injury with IDEA: Intraoperative Data Embedded Analytics (2019)

Postoperative AKI prediction was improved with high sensitivity and specificity through a machine learning approach that dynamically incorporated intraoperative data.
Blood Circulation-Prolonging Peptides for Engineered Nanoparticles Identified via Phage Display (2019)

Sustaining blood retention for theranostic nanoparticles is a big challenge. Various approaches have been attempted and have demonstrated some success but limitations remain. We hypothesized that peptides capable of increasing blood residence time for M13 bacteriophage, a rod-shaped nanoparticle self-assembled from proteins and nucleic acids, should also prolong blood circulation for engineered nanoparticles. Here we demonstrate the feasibility of this approach by identifying a series of blood circulation-prolonging (BCP) peptides through in vivo screening of an M13 peptide phage display library. Intriguingly, the majority of the identified BCP peptides contained an arginine-glycine-aspartic acid (RGD) motif, which was necessary but insufficient for the circulation-prolonging activity. We further demonstrated that the RGD-mediated specific binding to platelets was primarily responsible for the enhanced blood retention of BCP1. The utility of the BCP1 peptide was demonstrated by fusion of the peptide to human heavy-chain ferritin (HFn), leading to significantly improved pharmacokinetic profile, enhanced tumor cell uptake and optimum anticancer efficacy for doxorubicin encapsulated in the HFn nanocage. Our results provided a proof-of-concept for an innovative yet simple strategy, which utilizes phage display to discover novel peptides with the capability of substantially prolonging blood circulation for engineered theranostic nanoparticles.
<title>Electrophotographic properties of thiophene derivatives as charge transport material</title> (1991)

The authors investigated electrophotographic properties of some substituted thiophenecarboxaldehyde-hydrazones as charge transport materials in layered-type photoreceptors from a viewpoint of molecular design. The values of optical bandgap [Eg(opt)] of the polycarbonate films doped with the hydrazones decrease from 2.9 to 2.4 eV with increasing thiophene rings and, therefore, with increasing (pi) -conjugation length. The Eg(opt) values for the thiophene derivatives are smaller than those for phenyl derivatives. Hole mobilities in the polycarbonate films doped with the hydrazones (50% in weight ratio) fall in the range between 1X10MIN6 and 5X10MIN6 cm(superscript 2/Vsec. Any significant difference was not found between the hole drift mobilities for the thiophene derivatives and those for the phenyl derivatives. Hole mobility and charge injection efficiency of the thiophene derivatives increase with decreasing Eg(opt). The hydrazone derivatives with longer (pi) -conjugation length show higher hole mobility and higher charge injection efficiency. And the thiophene derivative shows higher injection efficiency and larger total carrier quantity than the phenyl derivative. The thiophene derivative is superior to the phenyl derivative as a charge transport dopant.
A modified adaptive transform coding scheme with post-processing-enhancement (2005)

The purpose of this paper is to describe a scheme for low-bit-rate transmission of speech. The scheme consists of a cascade of a codec with a post-processor. The codec is based on a modified version of the LPC Vocoder Driven Adaptive Transform Coding algorithm. The Post-Processor performs a short-time Fourier analysis/synthesis at the receiver output and, by exploring the known structure of the quantization noise introduced by the codec, it is capable of speech enhancement. The performance of this scheme will be demonstrated at 9.6 kb/s and at 7.2 kb/s.
100 GHz GaAs MMIC sampling head (2003)

A room-temperature GaAs diode sampling head was fabricated which has an estimated bandwidth of 130 GHz. This speed is attained with a monolithic sampling bridge design which allows integration with a nonlinear transmission line (NLTL) strobe pulse generator on the same GaAs IC. The 4-ps falltime of the test NLTL measured by the diode sampler is shown. The sampler is within 0.5% of linearity from 0 to 0.4 V. The voltage conversion loss is less than 5% at 5 GHz while the power conversion loss is 43 dB due to the relatively high impedance of the equivalent time output. The minimum detectable voltage is 90 nV/ square root Hz. This sampling head IC, when packaged in a coplanar probe, will allow on-wafer measurements at frequencies in excess of 100 GHz.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>