gebhart/patrepeval huggingface dataset:
Dewatering of biological slurry by using water‐absorbent polymer gel (1989)

A new concentrating/dewatering process utilizing water-absorbent polymer gels as dewatering media for biological slurries is proposed. The polymer gel applied to the process should be of porous structure for rapid water-absorption and of larger size for easier separation of gel from slurry. Poly(vinylmethylether) gel (PVMEG) prepared by gamma-ray irradiation was found to be suitable for the purpose. PVMEG swelled or shrunk reversibly in response to temperature and its transition temperature was 310K. Slurries of different properties were dewatered quite well by applying PVMEG. The water-absorbability of the gel was unaffected by the properties of organic substances contained in the slurries. An engineering calculation of the proposed dewatering process, which was called "gel dewatering process," revealed that the process was promising for concentrating/dewatering microbe-rich slurries in the respect that it would be composed of compact and simple apparatuses and be an energy saving system.
10 channel, 28 Gbaud PM-QPSK, monolithic InP Terabit Superchannel receiver PIC (2011)

We present a 10 channel, polarization-multiplexed QPSK receiver photonic integrated circuit, with 25 GHz channel spacing, operating at 28 Gbaud (112 Gbit/s per channel). With 10 channels operating, this is a Terabit Superchannel receiver.
Enhancing Hydrogen Evolution Activity in Water Splitting by Tailoring Li <sup>+</sup> -Ni(OH) <sub>2</sub> -Pt Interfaces (2011)

Improving the sluggish kinetics for the electrochemical reduction of water to molecular hydrogen in alkaline environments is one key to reducing the high overpotentials and associated energy losses in water-alkali and chlor-alkali electrolyzers. We found that a controlled arrangement of nanometer-scale Ni(OH)(2) clusters on platinum electrode surfaces manifests a factor of 8 activity increase in catalyzing the hydrogen evolution reaction relative to state-of-the-art metal and metal-oxide catalysts. In a bifunctional effect, the edges of the Ni(OH)(2) clusters promoted the dissociation of water and the production of hydrogen intermediates that then adsorbed on the nearby Pt surfaces and recombined into molecular hydrogen. The generation of these hydrogen intermediates could be further enhanced via Li(+)-induced destabilization of the HO-H bond, resulting in a factor of 10 total increase in activity.
<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>C</mml:mi></mml:math>-Axis Electrical Conductivity of Graphite (1956)

Small crystals of natural graphite showing no evidence of twinning were found in a sample of marble from the Lead Hill mine (Ticonderoga, New York). They were isolated, handled very carefully to avoid deformation, and their $c$-axis conductivity determined. It was found to be about 2\ifmmode\times\else\texttimes\fi{}${10}^{2}$${(\mathrm{ohm}\mathrm{cm})}^{\ensuremath{-}1}$, in accord with previous measurements of less perfect crystals. It is shown that much of the variability in the measurements of larger, less perfect crystals is caused by nonuniform current flow. However, evidence is adduced to indicate that the actual $c$-axis conductivity of natural graphite crystals does vary somewhat.
Abstract 2943: Novel combination therapy of DNMT inhibitor SGI-110 and PARP inhibitor BMN-673 (talazoparib) for BRCA-proficient ovarian cancer (2015)

Abstract Ovarian cancer (OC) is initially chemoresponsive but the majority of patients relapse after first line platinum-, taxane-based chemotherapy. Recurrence has been shown to be associated with increased DNA damage response (DDR) mediated by poly-(ADP)-ribose polymerase 1/2 (PARP1/2), which can be therapeutically targeted by PARP inhibitors (PARPi). Although PARPi are indicated for platinum-responsive, BRCA-mutated OC, most OC patients have BRCA-proficient disease. Based on our previous studies supporting a role for DNA methylation in chemoresistant OC, mediated by the enzyme DNA methyltransferase 1 (DNMT1), and reports on a functional role for DNMT1 in DNA double strand break repair mediated by BRCA1/2, we hypothesized that combining DNMTi and PARPi will impair BRCA-mediated DDR, resulting in cytotoxicity in OC cells. A panel of OC cell lines, including A2780 (platinum sensitive, BRCA-wild type (wt)), A2780-cp and HeyC2 (platinum resistant, BRCA-wt) and Kuramochi (platinum resistant, BRCA2 mutant) were examined for cell growth using colony formation assays after treatment with DNMTi SGI-110 (5, 20, or 100nM) and PARPi talazoparib (1 or 10nM), alone or in combination. Combination treatment schemas consisted of: 1) “priming”: SGI-110 for three days, 24 hour recovery, then talazoparib treatment on Day 5 or 2) “co-administration”: talazoparib administration on day 1 and SGI-110 treatment on days 1-3. Colony formation was inhibited by talazoparib alone in all cell lines but in a dose-dependent manner. Decreased colony formation after SGI-110 alone (20 or 100 nM) was observed only in Kuramochi cells. Combination drug treatments resulted in significant reductions in colony formation. For example, regardless of BRCA and platinum sensitivity status, co-administration of SGI-110 and talazoparib reduced (P&lt;0.05) cell survival, albeit%survival was dependent on drug dose and OC cell line. In general, priming with SGI-110 prior to treatment with talazoparib reduced (P&lt;0.05) survival of A2780, Kuramochi and HeyC2 (majority of combinations tested); however, decreased (P&lt;0.05) survival of A2780-cp was observed only after priming with 100 nM SGI-110. In summary, talazoparib combined with SGI-110 displayed effective cytotoxicity in OC cell lines harboring either wt- or mutant-BRCA, indicating that this DNMTi-PARPi drug combination impairs BRCA-mediated DDR and may represent an effective treatment regimen for OC. Citation Format: Nicholas Pulliam, Pietro Taverna, John Lyons, Kenneth P. Nephew. Novel combination therapy of DNMT inhibitor SGI-110 and PARP inhibitor BMN-673 (talazoparib) for BRCA-proficient ovarian cancer. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 2943. doi:10.1158/1538-7445.AM2015-2943
A Fast and Stable Force-Directed Placement with Implicit Buffer Planning (2006)

As technology advances, the number of required buffers increases significantly and it is desirable to plan buffers at placement stage. This paper studies the approach of planning buffers during analytical placement. First, a fast and stable force-directed placement is introduced, which is averagely 1.71 times as fast as Capo8.8, a state-of-the-art placement tool, with little degradation of wire-length. Then a new model for planning buffers during placement is proposed, which can efficiently ensure the convergence of placement iterations only by modeling buffers implicitly with changed density distribution and modified connectivity weight between drivers and receivers. Also, equivalent candidate positions for buffer insertion are explored to resolve buffer overlaps. Experiments show that compared with previous buffer planning methods, our new approach can achieve greater efficiency as well as quality improvement
A monolithic multiplexed 16-wavelength WDM transmitter with accurate channel spacing (1997)

1. Introduction There are two main categories of needed WDM sources: those that output one wavelength at a time onto which data is usually externally modulated; and those that output several wavelengths simultaneously, onto each of which data is usually directly modulated. The first category is generally employed for long transmission distances because of the low chirp, while the second category is generally employed for medium and short transmission distances because of the low cost per wavelength. Here we present an ideal source for the second category. Early sources for the second category consisted of a collection of discrete fiber-coupled distributed feedback (DFB) lasers, one for each wavelength111. More recently, to be more cost- effective, arrays of DFB lasers have been integrated with star couplers onto single chips[2,31. However, DFB arrays do not have an intrinsically controlled channel spacing, and the combing loss in the star coupler increases linearly with channel number. To insure the channel spacing accuracy necessary for WDM networks, it is advantageous to have all the channels in the source locked to the same filter element. The first semiconductor laser operating on this principle was the Multistripe Array Grating Integrated Cavity (MAGIC) laser[4] based on a reflective grating. Since then, significant progress has been achieved on a semiconductor laser based on a transmissive grating, the waveguide grating router multiffequency laser (MFL)[51. Here, we present the MFL's recent results.
HISTOPATHOLOGICAL EFFECTS OF SOLDERING FUMES ON RESPIRATORY TRACT EPITHELIUM IN RAT (2008)

: Background: Fumes generating during soldering process are a group of metal vapors and gases
such as tin, lead and formaldehyde which are one of the main reasons for lung diseases in solders.
Respiratory epithelium in trachea is the first biological barrier which responds to these fumes. The
aim of this study was to identify the quantitative effects of these fumes in respiratory epithelium of
rats.
Materials and Methods: A total number of 48 adult male Sprague Dawley rats were randomly
divided into experimental (n=30) and control (n=18) groups. Each group was subdivided into 2, 4
and 6-week subgroups based on the time of tissue sampling. After adaptation to standard situation
in animal house, rats in experimental group were exposed to soldering fumes for 1 hour in exposure
chamber (0.83m3). Air sampling from the exposure chamber was done daily with two different
methods. According to the schedule, tissue specimens were taken from trachea in deep anesthesia.
After processing, all samples were sectioned and stained and the thickness of the respiratory
epithelium of trachea was measured under light microscopy.
Results: There was a significant difference between all of control and experimental subgroups
(p<0.000). There was also a significant difference between experimental groups of 6-week
subgroup with 2-week subgroup (p<0.001). The amount of the formaldehyde, tin (Sn) and lead (Pb)
in gas exposure chamber was 0.193 mg/m3, 0.35 mg/m3 and 3 mg/m3 respectively.
Conclusion: It seems that the respiratory epithelium of the trachea responds to the soldering
fumes and the changes in epithelial thickness are time dependent.
Weighted rake receiver for UWB communications with channel estimation errors (2005)

In this paper, a new weighted max-ratio-combining (MRC) selective Rake (SRake) receiver is proposed for a pulse based UWB system with channel estimation errors. Thanks to the prior knowledge of the multipath channel, our new method can further improve the BER performance compared with the conventional MRC Rake receiver. We analyze the new scheme in a theoretical way and the performance improvement is also evaluated in the IEEE 802.15.3a ultra-wideband channel model through computer simulation.
Mechanical design of the cartridge and transport for the IBM 3480 Magnetic Tape Subsystem (1986)

The IBM 3480 Magnetic Tape Subsystem has achieved significant improvements over its predecessor, the 3420, in speed, data density, and floor-space requirements. The 3-megabyte-per-second data rate of the 3480, which is 2.4 times that of the 3420, was accomplished through the use of chromium-dioxide tape stored in a compact, single-reel cartridge threaded to a take-up reel. A sixfold increase in data density over the 3420 allowed reduction of the size of the 3480 reel, which was essential for rapid acceleration of the tape in the 3480's reel-to-reel transport. The increased data density also demanded substantial improvements in tape guiding and tape-motion control. This paper describes how mechanical analysis and design contributed to the achievement of these advances and aided in overcoming the ensuing problems.
In-cache pre-processing and decode mechanisms for fine grain parallelism in SCISM (2002)

A study was initiated that investigated detractors to parallelism and implementation constraints associated with the critical paths in the design of fine grain parallel machines. The outcome of the research has been a new machine organization that facilitates and improves parallel instruction issue and possible increases in cycle time and by improving the instruction-level parallelism, using specialized hardware. The authors describe the attributes of the proposed machine organization related to the analysis of instruction sequences for the parallel issue and execution. They also describe the permanent preprocessing in the cache that allows for the determination of instructions for parallel execution prior to the instruction fetch and issues.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Excited-State Complexes of Conjugated Polymers: Novel Photophysical Processes and Optoelectronic Materials. (1995)

Abstract : Although the ground-state charge transfer complexes of pi-conjugated polymers have been widely investigated in the past two decades, the corresponding excited-state complexes were only recently discovered. The results of our extensive studies of intermolecular excimers and exciplexes of many conjugated polymers will be presented in the talk. The observation of excimer and excimer emission of many conjugated polymers provides a new model of the photophysics of the materials. It will be shown that the modified Birks' mechanism of intermolecular excimers can explain all the essential features of the luminescence of conjugated polymers. The luminescence and charge photogeneration in exciplexes of conjugated polymers with donor triarylamines will also be presented. jg
Hair Cell Condition and Auditory Nerve Response in Normal and Noise-Damaged Cochleas (1979)

Histological and physiological data are presented from cats born and raised in a low-noise environment and from cats with long-standing, noise-induced threshold shifts. Even after a 1 1/2-year survival from acoustic trauma, there were threshold elevations of roughly 40 dB in the response of single auditory-nerve fibers which could not be correlated with significant loss of hair cells. An attempt was made to correlate these threshold differences with differences in the condition of the sensory cells as seen in a light-microscopic examination of epon-embedded surface preparations. Of all the histological features evaluated, the orderlines of the stereocilia, on both inner and outer hair cells, showed the closest correlation with single-unit thresholds. In the final analysis, most of threshold shift in the noise-exposed ears could be accounted for by loss or damage to sensory cells clearly visible under the light microscope.
Activated N-nitrosocarbamates for regioselective synthesis of N-nitrosoureas (1982)

A practical and convenient method for synthesizing antitumor compounds, N-alkyl-N-nitrosoureas, regioselectively nitrosated on the nitrogen atom bearing the alkyl group is proposed. N-Alkyl-N-nitrosocarbamates are interesting intermediates in these syntheses and yield, by reaction with amino compounds, the regioselectively nitrosated N-alkyl-N-nitrosoureas. As an interesting example, N,N'-bis[(2-chloroethyl)nitrosocarbamoyl]cystamine, a new attractive oncostatic derivative, has been prepared. The cytotoxic activity of these various compounds were tested on L1210 leukemia.
Rapport sur le Mémoire présenté à la Section par M. le Dr H. Scaetta, intitulé : "Les famines périodiques dans le Ruanda". (1931)

info:eu-repo/semantics/published
Ferroelectric liquid-crystal polarization switching-based high-speed multiwavelength add/drop filters using fiber and array waveguide gratings (1998)

A number of approaches have been used to implement programmable add/drop optical filters for wavelength division multiplexed (WDM) optical communications. These include integrated-optic (10) acousto-optic tunable filters (AOTFs) [1], all-fiber mechanically tuned fiber Bragg grating (FBG) devices [2], 10 grating switch with 10 coupler devices [3], array waveguide grating (AWG) multiplexer with 10 thermo-optic switches [4], FBG devices with magnetic field tuning [5], JO Bragg gratings with multi-mode interference couplers [6], NxN wavelength grating routers and lxN mechanical switches [7], AWG multiplexer with manually simulated 2X2 switches [8], free-space diffraction gratings-based filter using a linear array twisted nematic liquid crystal device [9], 10 electro-optically controlled synthesized grating structure based filter [ 10], and bulk dual AOTF-based structures [ 1 1] .It is highly desirable to have a short reconfiguration time (e.g., 10 is), low optical crosstalk (e.g., -40 dB), low drive power (e.g., tens of mWs), low loss (e.g., 5 dB), add-drop filter. In addition, a low cost modular and scaleable filter design that is easily modifiable and repairable is also desirable. So far, to the best of the author's knowledge, no one filter satisfies all the mentioned requirements. In this paper, we propose three filter architectures based on high speed ferroelectric liquid crystal (FLC) devices, that have the potential to meet the above requirements.
General Properties and Synthesis of Transformerless Stacked Active Bridge Converters (2019)

Transformerless stacked active bridge (TSAB) converters are hybrid dc-dc converters that combine features of switched capacitor (SC) and dual-active-bridge (DAB) converters, and can achieve very high efficiency near their nominal conversion ratio, together with regulation capability using simple phase-shift control. Following a network-theoretic approach, this paper describes a systematic procedure for synthesis of TSAB converters starting from two-phase SC converters such as ladder, Dickson, Fibonacci, and other SC topologies. Furthermore, the same approach yields general topology-dependant properties of TSAB converters, including steady-state characteristics and component stresses.
Performance Analysis of a Variable Speed-Ratio Metal V-Belt Drive (1988)

A model of the metal V-belt drive (MBD), considering its detailed multiple-band and metal-block structure, and the ratio-change effect during its operation, is constructed and analyzed. A computational scheme is devised that adapts the analysis to the computation of the MBD’s performance for any specified drive-schedule. General performance characteristics of the MBD and an example illustrating its response to a given drive-schedule are presented. The use of the analysis and the computational scheme in the design of the MBD and in finding the optimum operating conditions is discussed.
Electrochemical Properties of Trirutile-type Li2TiF6 as Cathode Active Material in Li-ion Batteries (2010)

The electrochemical properties of lithium hexafluorometalates as positive electrode materials were studied. Trirutile-type Li2TiF6 was synthesized through a complex-formation reaction under mild temperature conditions. In addition, a spray-drying technique was used to obtain electrodes with a large surface area. The electrochemical performance of the resultant Li2TiF6 powders was investigated vs. Li metal as negative electrode. Li2TiF6 exhibited an initial discharge capacity of 100 mAh g−1 at 2.7 V.
LASER OSCILLATIONS AND SELF <i>Q</i>-SWITCHING IN TRIPLY ACTIVATED GLASS (1965)

First Page
Synthesis of methacrylic multi‐arm star copolymers by “arm‐first” group transfer polymerisation (1997)

Abstract Methacrylic star polymers were synthesized by the “arm‐first” method of star polymer formation by the addition of difunctional monomer, ethylene glycol dimethacrylate, to living linear poly(methyl methacrylate) as prepared by group transfer polymerisation (GTP). The effects of living polymer concentration and ratio of difunctional monomer to living polymer are discussed, and show how macromolecular design and control may be imposed on the number of arms and molecular weight of the star polymer. Diluting the difunctional crosslinking monomer with monomer has been examined with the view to establishing funtionalisation of the star core.
STREPTOMYCES ANTIBIOTICS. II. CRYSTALLINE STREPTOMYCIN TRIHYDROCHLORIDE—CALCIUM CHLORIDE DOUBLE SALT (1945)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSTREPTOMYCES ANTIBIOTICS. II. CRYSTALLINE STREPTOMYCIN TRIHYDROCHLORIDE—CALCIUM CHLORIDE DOUBLE SALTRobert L. Peck, Norman G. Brink, Frederick A. Kuehl Jr., Edwin H. Flynn, Alphonse Walti, and Karl FolkersCite this: J. Am. Chem. Soc. 1945, 67, 10, 1866–1867Publication Date (Print):October 1, 1945Publication History Published online1 May 2002Published inissue 1 October 1945https://pubs.acs.org/doi/10.1021/ja01226a517https://doi.org/10.1021/ja01226a517research-articleACS PublicationsRequest reuse permissionsArticle Views79Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Linear phase filter design on a time-domain basis (1981)

The maximum error between the input and output signals of filters is bounded. This bound is used to develop low-pass filter design procedures based on time domain errors. This technique is applied to phase-corrected Butterworth and Chebyshev filters.
Efficacy and safety of intravenous cyclophosphamide pulse therapy with oral prednisolone in the treatment of interstitial lung disease with systemic sclerosis: 4-year follow-up (2011)

Interstitial lung disease (ILD) is a noteworthy condition in the treatment of systemic sclerosis (SSc) because of its associated mortality and morbidity; however, the efficacy of various treatments for ILD has been controversial in previous reports. In this study, we examined the efficacy and safety of intravenous cyclophosphamide (IVCY) pulse therapy with prednisolone (PSL) for the treatment of ILD with SSc. A total of 121 patients with SSc were screened and evaluated for ILD, using high-resolution computed tomography of the chest, pulmonary function testing, and bronchoalveolar lavage. Thirteen patients with active ILD were enrolled in this study. The treatment protocol for ILD was 0.4 g/m2 of body surface area of IVCY monthly plus 0.8 mg/kg of body weight of PSL daily. Two to six doses of IVCY were administered, depending on the remission of ILD. Initial PSL doses were maintained for a month and then gradually tapered to 10 mg daily. An activity index of ILD showed improvements in all patients in the 12 months after the initial intervention; however, four patients experienced recurrence of ILD after 24 months, and one additional patient had recurrence of ILD after 36 months. Seven patients reached the 48-month point with no recurrence of ILD. This long observational study for 48 months showed the efficacy of IVCY with PSL for active alveolitis in the first year. However, because five patients had recurrence of ILD more than 1 year after the treatment, it would be necessary to consider maintenance therapy for ILD beyond 1 year.