gebhart/patrepeval huggingface dataset:
DHPLC Scoring of a SNP between Promoter Sequences of HMW Glutenin x-type Alleles at the <i>Glu-D1</i> Locus in Wheat (2003)

The promoter regions of HMW glutenin x-type genes at the Glu-D1 locus were surveyed for SNPs within a subpopulation of German bread wheat cultivars. On the basis of the promoter sequences of HMW glutenin subunit genes Glu-A1-x1, Glu-A1-x2, Glu-B1-x1, Glu-B1-x7, Glu-D1-x2, and Glu-D1-x5, an amplification refractory mutation system assay was designed to selectively amplify Dx-specific PCR fragments. Comparative sequence analysis among seven Glu-D1-x2 and seven Glu-D1-x5 wheat cultivars only confirmed a G-A transition in the promoter sequence to be a true polymorphism. SNP scoring by DHPLC of 95 German bread wheat cultivars, with the exception of cv. Anemos, showed that the transition completely agreed with the presence of HMW glutenin subunits 1Dx5 + 1Dy10 in SDS-PAGE. Therefore, the developed DHPLC assay is suitable for high-throughput genotyping to assist the selection of HMW glutenin genes in wheat quality breeding programs.
TRAF7 Potentiates MEKK3-induced AP1 and CHOP Activation and Induces Apoptosis (2004)

The tumor necrosis factor receptor-associated factor (TRAF) protein family members are critically involved in activation of NF-kappaB, JNK, and p38 activation triggered by tumor necrosis factor (TNF) receptor family members and toll/interleukin-1 receptor (TIR)-containing receptors. TRAF proteins (except for TRAF1) contain an N-terminal RING finger domain that is essential for their functions. In this report, we identified a protein designated as TRAF7, which contains a RING finger domain and a zinc finger domain that are mostly conserved with those of TRAFs. TRAF7 also contains seven WD40 repeats at its C terminus. TRAF7 specifically interacted with MEKK3 and potentiated MEKK3-mediated AP1 and CHOP activation. Depletion of TRAF7 by antisense RNA inhibited MEKK3-mediated AP1 and CHOP activation. Moreover, overexpression of TRAF7 induced caspase-dependent apoptosis. Domain mapping experiments indicated that TRAF7 potentiated MEKK3-mediated AP1 and CHOP activation and induced apoptosis through distinct domains. Our studies identified a novel TRAF family member that is involved in MEKK3 signaling and apoptosis.
How to reduce light leakage and clipping in local‐dimming liquid‐crystal displays (2009)

Abstract— In conventional LCDs, the backlight is set to maximum luminance regardless of the image. For dark scenes, this approach causes light leakage and power waste. Especially, light leakage in dark scenes degrades the contrast ratio of LCDs; to circumvent this problem, local‐dimming systems have been proposed. In these systems, the LED backlight is divided into several local blocks and the backlight luminance of each local block is controlled individually, and pixel values are adjusted simultaneously according to the luminance profile of the dimmed backlight. In this paper, a method of determining the LED backlight luminance of each local block depending on the image is proposed; this method significantly improves the image quality of LCDs. First, we introduce methods of quantifying light‐leakage at dark gray levels and clipping at bright gray levels. Then, the proposed method to determine the dimming duty, which controls the LED backlight luminance by compromising between these two measures, was derived. The proposed algorithm preserves the original image with little clipping distortion and effectively reduces light leakage.
Corn Proteins (1937)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCorn ProteinsJ. F. WalshCite this: Ind. Eng. Chem. 1937, 29, 6, 673–674Publication Date (Print):June 1, 1937Publication History Published online1 May 2002Published inissue 1 June 1937https://doi.org/10.1021/ie50330a016RIGHTS & PERMISSIONSArticle Views224Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (288 KB) Get e-Alerts
Surface and pore structure of deoiled acid‐and heat‐treated spent bleaching clays (1997)

Abstract Samples of spent bleaching clay were deoiled by hexane, methanol, hexane‐methanol, and supercritical CO 2 extractions. The deoiled clays were regenerated by acid and heat treatments. Nitrogen adsorption isotherms for these samples are type IV with hysteresis loops corresponding to type H3, indicating slit‐shaped pores. Used deoiled and dried samples have smaller surface areas and pore volumes than unused clay. The surface areas and pore volumes increased after heat treatment. Acidified heat‐treated deoiled samples have smaller surface areas and greater pore volumes than unused clay, except for the methanol‐deoiled sample. Thus, heat and acid treatments removed substances adsorbed in the pores that were not removed by solvents or CO 2 extraction. This was confirmed from the ratios of the cumulative surface area/BET surface area, as well as analysis of the pore size distributions, which indicated an increase in mesopores with radii of between 25 and 100 Å. The t ‐plots showed that smaller pores with sizes between 7 and 25 Å, present originally in the unused clays, were closed by heat treatment. These pores were absent in the deoiled and the heat‐treated samples except for the heat‐treated sample that was deoiled by hexane followed by methanol. Smaller pores, accompanied by an increase in surface area, were also observed for all deoiled samples after acid and heat treatments.
Enzyme Immobilization by Covalent Bonding (2003)

Enzyme immobilization by covalent bonding to an insoluble polymer has the supposed advantage of irreversible binding of the enzyme to the support matrix. Many of the bonds commonly employed are not 100% stable in use, however. Unless some care is taken to ensure that the enzyme can withstand the reaction conditions, substantial loss of enzyme activity will occur. Even under favorable conditions, 60% loss of activity is not uncommon.
Fractionation of Conjugated Linoleic Acid Isomers by Selective Hydrolysis with Candida rugosa Lipase (2003)

It was attempted to prepare cis-9, trans-11 conjugated linoleic acid (c9,t11-CLA) and t10,c12-CLA concentrates that can be used as foods. A free fatty acid mixture (FFA-CLA) containing almost equal amounts of c9,t11- and t10,c12-CLAs was esterified with glycerol using immobilized Rhizomucor miehei lipase, and the resulting acylglycerols (Gly-CLA) were purified by molecular distillation. Contents of c9,t11- and t10,c12-CLAs in Gly-CLA were the same as those in FFA-CLA: c9,t11-CLA, 33.7 wt%; t10,c12-CLA, 34.5 wt%. Gly-CLA was first hydrolyzed with an equal weight of water and 1.0 U/g-mixture of Candida rugosa lipase, and c9,t11-CLA-rich FFAs were prepared by molecular distillation: purity of c9,t11-CLA based on the total content of c9,t11- and t10,c12-CLAs, 72.9%. Meanwhile, purity of t10,c12-CLA in acylglycerols was 65.0%. To further increase the purity, the acylglycerols were hydrolyzed again with 15 U/g-mixture of C. rugosa lipase, resulting in enrichment of t10,c12-CLA in acylglycerols (purity of t10,c12-CLA, 80.4%). Non-selective hydrolysis of t10,c12-CLA-rich acylglycerols with 200 U/g-mixture of C. rugosa lipase produced t10,c12-CLA-rich FFAs (purity of t10,c12-CLA, 81.5%). In addition, c9,t11-CLA-rich FFAs were successfully esterified with glycerol using immobilized R. miehei lipase, and c9,t11-CLA-rich acylglycerols can be synthesized (purity of c9,t11-CLA, 73.0%). The process was composed of reactions with C. rugosa and R. miehei lipases, which can be used for production of foods, and molecular distillation. Hence, the c9,t11- and t10,c12-CLA concentrates can be used as foods.
The Relationship Between North Carolina Secondary Agriculture Teachers' Use Of Time Management Practices And the Quality Of The Supervised Agricultural Experience Program Component (1993)

No abstract available
Impurity effects in partially ionized beam metal via filling (1990)

One of the most outstanding problems in multilevel interconnect technology is the filling and planarization of metals in deep vias and trenches. Due to the shadowing effect, metal via filling with large aspect ratio using conventional deposition techniques is known to be very difficult. A directional deposition technique, known as partially ionized beam deposition (PIB) shows that oxide trenches with an aspect ratio of 3 can be filled wall to wall with Al or an Al–Cu alloy. Unlike conventional deposition techniques, Al films deposited by the PIB technique grow layer by layer and do not develop the usual overhang structure at the top corner of the vias. In this paper, a detailed study on the effects of impurities, either from a poor vacuum condition or from the substrate, on the PIB via/trench filling is presented. It is found that the surface mobility is greatly reduced as the vacuum pressure is increased from 10−4 Pa. It is also shown that the minimum substrate temperature (normally less than 200 °C) required for PIB via/trench filling is different for different types of oxide such as thermally grown, plasma enhanced chemical vapor deposition (PECVD), and tetraethylorthosilicate (TEOS) oxides.
Long-Term Mortality after Transfusion-Associated Non-A, Non-B Hepatitis (1992)

In this long-term follow-up study, there was no increase in mortality from all causes after transfusion-associated non-A, non-B hepatitis, although there was a small but statistically significant increase in the number of deaths related to liver disease.
Broad-band, multi-harmonic frequency domain behavioral models from automated large-signal vectorial network measurements (2005)

This paper presents an extended nonlinear black-box behavioral model in the frequency domain, automated experimental identification of the model from large-signal vector network measurements, and extensive experimental validation of its application to real microwave ICs. The model is a broad-band extension of the multi-harmonic "linearized scattering function" theory. The characterization is based on large-signal vector network measurements where harmonic perturbations are applied, in phase and in quadrature, to a component excited at the input by a large amplitude tone. The experiment design and model generation are simple and highly automated. The derived model is shown to be valid for both small and large amplitude drive signals, correctly predict even and odd harmonics, and simulate, accurately, load-pull behavior far from 50 ohms. The model is implemented in Agilent ADS.
Genetic and Functional Diversity of Pseudomonas aeruginosa Lipopolysaccharide (2011)

Lipopolysccharide (LPS) is an integral component of the Pseudomonas aeruginosa cell envelope, occupying the outer leaflet of the outer membrane in this Gram-negative opportunistic pathogen. It is important for bacterium-host interactions and has been shown to be a major virulence factor for this organism. Structurally, P. aeruginosa LPS is composed of three domains, namely, lipid A, core oligosaccharide, and the distal O antigen (O-Ag). Most P. aeruginosa strains produce two distinct forms of O-Ag, one a homopolymer of D-rhamnose that is a common polysaccharide antigen (CPA, formerly termed A band), and the other a heteropolymer of three to five distinct (and often unique dideoxy) sugars in its repeat units, known as O-specific antigen (OSA, formerly termed B band). Compositional differences in the O units among the OSA from different strains form the basis of the International Antigenic Typing Scheme for classification via serotyping of different strains of P. aeruginosa. The focus of this review is to provide state-of-the-art knowledge on the genetic and resultant functional diversity of LPS produced by P. aeruginosa. The underlying factors contributing to this diversity will be thoroughly discussed and presented in the context of its contributions to host-pathogen interactions and the control/prevention of infection.
3 crónicas españolas: Zaragoza (1952)

Open bladder neck before urethroplasty may herald postoperative incontinence which may be predicted by radiographic and cystoscopic features. Evaluation of the risk of postoperative incontinence may be valuable, and eventually guide the necessity and timing of anti-incontinence surgery, although our preference remains to manage the pelvic fracture urethral distraction defects and bladder neck problem sequentially. Bladder neck reconstruction provides good postoperative continence rates and is our technique of choice.
Development of a 3D tongue motion visualization platform based on ultrasound image sequences (2015)

International audience
ChemInform Abstract: Synthesis of Benzhydryl 2α‐(Chloromethyl)‐2β‐methyl‐6,6‐dihydropenam‐3α‐carboxylate 1,1‐Dioxide (I): The 2α‐Isomer of the Potent β‐Lactamase Inhibitor BL‐P2013. (1989)

ChemInformVolume 20, Issue 6 Natural Products ChemInform Abstract: Synthesis of Benzhydryl 2α-(Chloromethyl)-2β-methyl-6,6-dihydropenam-3α-carboxylate 1,1-Dioxide (I): The 2α-Isomer of the Potent β-Lactamase Inhibitor BL-P2013. S. N. MAITI, S. N. MAITI SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this authorP. SPEVAK, P. SPEVAK SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this authorK. OGAWA, K. OGAWA SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this authorR. G. MICETICH, R. G. MICETICH SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this author S. N. MAITI, S. N. MAITI SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this authorP. SPEVAK, P. SPEVAK SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this authorK. OGAWA, K. OGAWA SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this authorR. G. MICETICH, R. G. MICETICH SynPhar Lab. Inc., Edmonton, Alberta, Canada T6E 5V2Search for more papers by this author First published: February 7, 1989 https://doi.org/10.1002/chin.198906319AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume20, Issue6February 7, 1989 RelatedInformation
Increased Synaptic Dopamine in the Putamen in Restless Legs Syndrome (2012)

Given the lack of any difference in either β(max) or K(d) and the prior studies supporting an increase in presynaptic dopaminergic activity, the current changes found in D2R-BP likely reflect an increase in synaptic dopamine.
Direct Formation of Micro-/Nanocrystalline 2,5-Dimethyl-<i>N</i>,<i>N</i>‘-dicyanoquinonediimine Complexes on SiO<sub>2</sub>/Si Substrates and Multiprobe Measurement of Conduction Properties (2005)

Multiprobe measurements were performed on tiny single crystals of DMe-DCNQI complexes prepared directly on SiO2/Si substrates. The differences in conduction properties between the micro- and nanocrystals and bulk crystals were observed.
Identification of Two Novel HLA‐A<sup>∗</sup>0201‐Restricted CTL Epitopes Derived from MAGE‐A4 (2010)

MAGE-A antigens belong to cancer/testis (CT) antigens that are expressed in tumors but not in normal tissues except testis and placenta. MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials. MAGE-A4 antigen is extensively expressed in various histological types of tumors, so it represents an attractive target for tumor immunotherapy. In this study, we predicted HLA-A*0201-restricted cytotoxic T lymphocyte (CTL) epitopes of MAGE-A4, followed by peptide/HLA-A*0201 affinity and complex stability assays. Of selected four peptides (designated P1, P2, P3, and P4), P1 (MAGE-A4(286-294), KVLEHVVRV) and P3 (MAGE-A4(272-280), FLWGPRALA) could elicit peptide-specific CTLs both in vitro from HLA-A*0201-positive PBMCs and in HLA-A*0201/K(b) transgenic mice. And the induced CTLs could lyse target cells in an HLA-A*0201-restricted fashion, demonstrating that the two peptides are HLA-A*0201-restricted CTL epitopes and could serve as targets for therapeutic antitumoral vaccination.
Iminophosphoranes: Useful Building Blocks for the Preparation of Nitrogen-Containing Heterocycles (1994)

The almost centenarian reaction of iminophosphoranes with carbonyl or heterocumulene compounds (aza-Wittig reaction) is presented in this review, but with focus mainly on publications of the last decade. Both inter- and intramolecular versions of the aza-Wittig reaction are discussed, including for the latter mono and tandem cyclizations. The feasibility of preparing several kinds of nitrogen-containing heterocycles by this method has been systematically examined. Several successful examples of the synthesis of natural products, using the iminophosphorane-mediated cyclization as the key step, have demonstrated the maturity of the field and its excellent prospects. 1. Introduction 2. Intermolecular Aza-Wittig Reaction 3. Intramolecular Aza-Wittig Reaction 3.1. Ketones 3.2. Esters 3.3. Acyl Chlorides 3.4. Amides 3.5. Carboxylic Acid Anhydrides 4. Reaction of Iminophosphoranes with Alcohols and Oxiranes 5. Tandem Reactions 5.1.Tandem Aza-Wittig/Electrocyclic Ring Closure 5.1.1.Pyrido Annulation 5.1.1.1. Synthesis of c-Fused Pyridines 5.1.1.2. Synthesis of b-Fused Pyridines 5.1.2. Pyrimido Annulation 5.2. Tandem Aza-Wittig/Heterocumulene-Mediated Annulation 6. Consecutive Processes 7. Cyclization of Phosphazides
Understanding Ultra-Thin Film Resist and Underlayer Performance through Physical Characterization (2010)

The physical characterization of extreme ultraviolet (EUV) ultra-thin underlayers (ULs) and their effects on photoresist EUV lithographic performance was investigated. UL polymer compositions were modeled to identify polymer compositions that would encompass a range of glass transition temperatures (Tg) and surface polarities. Eight UL polymers compositions were synthesized and characterized, demonstrating that polymer composition can dictate the surface polarity and Tg properties of cross-linked UL films. The Tg of UL films drops significantly for film thicknesses below ~30 nm. EUV imaging of open source and commercial resists on the eight UL films was evaluated. Resist adhesion improved when the surface polarity of the underlayers decreased. It was discovered that the coefficient of thermal expansion (CTE) plays an important role in determining the adhesion of resist to underlayers.
Mitomycin C in the Treatment of Carcinoma of the Head and Neck* (1967)

GRAHAM, WILLIAM P. III M.D.; RAVDIN, ROBERT G. M.D.; CRICHLOW, ROBERT W. M.D.; EISMAN, SYLVAN H. M.D. Author Information
Mechanism of Palladium Complex-Catalyzed Enantioselective Mannich-Type Reaction:  Characterization of A Novel Binuclear Palladium Enolate Complex (1999)

Studies on the enantioselective addition of enol silyl ethers to imines catalyzed by optically active palladium diaquo complexes 3 or binuclear palladium μ-hydroxo complex 4 are described, with particular focus on the mechanistic aspects. Asymmetric induction in the reaction using [Pd((R)-binap)(H2O)2]2+(BF4-)2 (3a) was quite sensitive to the reaction conditions, suggesting unfavorable effects of HBF4 generated from 3a in situ. Novel optically active binuclear μ-hydroxo complexes [{Pd((R)-binap)(μ-OH)}2]2+(BF4-)2 (4a), [{Pd((R)-tol-binap)(μ-OH)}2]2+(BF4-)2 (4b), [{Pd((R)-binap)(μ-OH)}2]2+(TfO-)2 (4c), and [{Pd((R)-tol-binap)(μ-OH)}2]2+(TfO-)2 (4d) were prepared and were found to be better catalysts for the asymmetric Mannich-type reaction. Benzoylalanine derivatives 5 were obtained in excellent chemical and optical yields (up to 90% ee). Mechanistic studies using 1H NMR and electrospray ionization mass spectrometry indicated that a unique binuclear palladium-sandwiched enolate 12 was involved in the reaction of enol silyl ether 1 with imine 2 catalyzed by 4.
Transmit Wiener filter for the downlink of TDDDS-CDMA systems (2003)

We derive the transmit Wiener filter for DS-CDMA systems which depends upon the noise power at the receivers. We show that the transmit Wiener filter converges to the transmit matched filter and the transmit zero-forcing filter for low and high signal-to-noise-ratio, respectively. Simulation results show the superiority of the transmit Wiener filter compared to the other two transmit filters. Moreover, we observe that the application of the three transmit filters and the respective receive filters lead to similar results.
Sugar-glycerol cofermentations in lactobacilli: the fate of lactate (1992)

The simultaneous fermentation of glycerol and sugar by lactobacillus brevis B22 and Lactobacillus buchneri B190 increases both the growth rate and total growth. The reduction of glycerol to 1,3-propanediol by the lactobacilli was found to influence the metabolism of the sugar cofermented by channelling some of the intermediate metabolites (e.g., pyruvate) towards NADH-producing (rather than NADH-consuming) reactions. Ultimately, the absolute requirement for NADH to prevent the accumulation of 3-hydroxypropionaldehyde leads to a novel lactate-glycerol cofermentation. As a result, additional ATP can be made not only by (i) converting pyruvate to acetate via acetyl phosphate rather than to the ethanol usually found and (ii) oxidizing part of the intermediate pyruvate to acetate instead of the usual reduction to lactate but also by (iii) reoxidation of accumulated lactate to acetate via pyruvate. The conversion of lactate to pyruvate is probably catalyzed by NAD-independent lactate dehydrogenases that are found only in the cultures oxidizing lactate and producing 1,3-propanediol, suggesting a correlation between the expression of these enzymes and a raised intracellular NAD/NADH ratio. The enzymes metabolizing glycerol (glycerol dehydratase and 1,3-propanediol dehydrogenase) were expressed in concert without necessary induction by added glycerol, although their expression may also be influenced by the intracellular NAD/NADH ratio set by the different carbohydrates fermented.
Development of resistant strains of <i>Staphylococcus epidermidis</i> on gentamicin-loaded bone cement in vivo (2002)

We have compared the rates of infection and resistance in an animal model of an orthopaedic procedure which was contaminated with a low-dose inoculum of Staphylococcus epidermidis. We randomised 44 Sprague-Dawley rats to have bone cement implanted subcutaneously containing either gentamicin or saline (control). The wound was inoculated with a dilute solution of gentamicin-sensitive Staphylococcus epidermidis. At two weeks the cement was retrieved and microbiologically tested. A lower overall rate of infection was seen in the gentamicin-loaded cement group, but there was a significantly higher rate of gentamicin-resistant infection in this group (Fisher’s exact test, p < 0.01). Antibiotic-impregnated cement has an optimum surface for colonisation and prolonged exposure to antibiotic allows mutational resistance to occur. Gentamicin-loaded cement may not be appropriate for revision surgery if it has been used already in previous surgery.