gebhart/patrepeval huggingface dataset:
The Reaction of ortho-Quinones and ortho-Quinonimines with Primary Amines (1943)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Reaction of ortho-Quinones and ortho-Quinonimines with Primary AminesGeorge McCoy and Allan R. DayCite this: J. Am. Chem. Soc. 1943, 65, 10, 1956–1959Publication Date (Print):October 1, 1943Publication History Published online1 May 2002Published inissue 1 October 1943https://pubs.acs.org/doi/10.1021/ja01250a041https://doi.org/10.1021/ja01250a041research-articleACS PublicationsRequest reuse permissionsArticle Views263Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Primary <i>in vitro</i> antibody responses by purified murine B lymphocytes in serum-free defined medium. (1981)

A serum-free medium formulation that allows a primary in vitro antibody response to the nonmitogenic thymic independent antigen TNP-AECM-Ficoll is described. Purified murine B lymphocytes and adherent accessory cells are required for optimal specific responses as well as for optimal B cell survival. The medium is based on Iscove's modification of Dulbecco's modified Eagle's medium and Ham's F-12 nutrient mixture. The serum-replacing components are insulin, transferrin, and progesterone. The survival of unstimulated murine T cells in this Iscove/F12 medium is poor, but B cells survive for relatively long periods of time. This medium should prove useful in defining the molecular requirements for B lymphocyte activation by antigen.
Magnetic field sensing in the underground construction environment (2003)

Industrial magnetic field sensing applications often address such problems as crack detection, gear tooth (or missing gear tooth) detection, tramp metal detection in a process stream, proximity detection, vehicle counting, and similar tasks. The general sensor community is little aware of another industrial application in which magnetic fields are used for short-range distance measurements and data communication in the underground construction environment. In such problems, the magnetic field sensor becomes an antenna for a magnetic field receiver. This paper discusses magnetic field sensing in two situations conventionally called locating and tracking applications encountered in underground construction. Problems of this type typically involve magnetic fields from line or dipole sources, respectively, giving equipment for each problem a particular physical structure and mathematical foundation.
Transport and Magnetic Properties of CPP-GMR Sensor With CoMnSi Heusler Alloy (2008)

We investigated structural and magnetic properties of CoMnSi (CMS) Heusler alloy films and giant magneto-resistance (GMR) ratio of current-perpendicular-to-plane (CPP) GMR sensor elements. The films were deposited with magnetron sputtering method and annealed at 673 K and 773 K. The CMS films were identified as B2 structure by using X-ray diffraction and the magnetization of the films were evaluated as 0.95 T. We fabricated the CPP-GMR sensors varying the composition of the CMS films, Co <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">48</sub> Mn <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">21</sub> Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">31</sub> (at. %) as Si-rich CMS and Co <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">51</sub> Mn <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">25</sub> Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">24</sub> (at. %) as CMS-ref, having a FeCo layer between the CMS and Cu spacer. It was found that the element with Si-rich CMS exhibited higher GMR ratio of 9.0% than that with CMS-ref. Our calculations indicate that larger spin polarization of contact region between the CMS film and the FeCo film relates to larger GMR ratio.
Separation and Classification of Lipids Using Differential Ion Mobility Spectrometry (2011)

Correlations between the dimensions of a 2-D separation create trend lines that depend on structural or chemical characteristics of the compound class and thus facilitate classification of unknowns. This broadly applies to conventional ion mobility spectrometry (IMS)/mass spectrometry (MS), where the major biomolecular classes (e.g., lipids, peptides, nucleotides) occupy different trend line domains. However, strong correlation between the IMS and MS separations for ions of same charge has impeded finer distinctions. Differential IMS (or FAIMS) is generally less correlated to MS and thus could separate those domains better. We report the first observation of chemical class separation by trend lines using FAIMS, here for lipids. For lipids, FAIMS is indeed more independent of MS than conventional IMS, and subclasses (such as phospho-, glycero-, or sphingolipids) form distinct, often non-overlapping domains. Even finer categories with different functional groups or degrees of unsaturation are often separated. As expected, resolution improves in He-rich gases: at 70% He, glycerolipid isomers with different fatty acid positions can be resolved. These results open the door for application of FAIMS to lipids, particularly in shotgun lipidomics and targeted analyses of bioactive lipids.
Road-adaptive nonlinear design of active suspensions (1997)

Recently (1995) we proposed a novel nonlinear control design for active suspensions, which features a filter whose bandwidth is a nonlinear function of suspension travel; this filter results in an improved tradeoff between ride comfort and rattlespace usage. In this paper we augment this controller with a new road-adaptive algorithm which continuously monitors suspension travel and adjusts online the shape of the filter nonlinearity in response to different road profiles. This adaptive design realizes the true potential of active suspensions, which is their ability to yield better performance over a much wider range of road surfaces than passive suspensions.
Effects of deamidation with chymotrypsin at pH 10 on the functional properties of proteins (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleEffects of deamidation with chymotrypsin at pH 10 on the functional properties of proteinsAkio Kato, Atsushi Tanaka, Yoshinori Lee, Naotoshi Matsudomi, and Kunihiko KobayashiCite this: J. Agric. Food Chem. 1987, 35, 2, 285–288Publication Date (Print):March 1, 1987Publication History Published online1 May 2002Published inissue 1 March 1987https://pubs.acs.org/doi/10.1021/jf00074a029https://doi.org/10.1021/jf00074a029research-articleACS PublicationsRequest reuse permissionsArticle Views280Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The leech product saratin is a potent inhibitor of platelet integrin α<sub>2</sub>β<sub>1</sub> and von Willebrand factor binding to collagen (2007)

Subendothelial collagen plays an important role, via both direct and indirect mechanisms, in the initiation of thrombus formation at sites of vascular injury. Collagen binds plasma von Willebrand factor, which mediates platelet recruitment to collagen under high shear. Subsequently, the direct binding of the platelet receptors glycoprotein VI and alpha2beta1 to collagen is critical for platelet activation and stable adhesion. Leeches, have evolved a number of inhibitors directed towards platelet-collagen interactions so as to prevent hemostasis in the host during hematophagy. In this article, we describe the molecular mechanisms underlying the ability of the leech product saratin to inhibit platelet binding to collagen. In the presence of inhibitors of ADP and thromboxane A2, both saratin and 6F1, a blocking alpha2beta1 mAb, abrogated platelet adhesion to fibrillar and soluble collagen. Additionally, saratin eliminated alpha2beta1-dependent platelet adhesion to soluble collagen in the presence of an Src kinase inhibitor. Moreover, saratin prevented platelet-rich plasma adhesion to fibrillar collagen, a process dependent upon both alpha2beta1 and von Willebrand factor binding to collagen. Furthermore, saratin specifically inhibited the binding of the alpha2 integrin subunit I domain to collagen, and prevented platelet adhesion to collagen under flow to the same extent as observed in the presence of a combination of mAbs to glycoprotein Ib and alpha2beta1. These results demonstrate that saratin interferes with integrin alpha2beta1 binding to collagen in addition to inhibiting von Willebrand factor-collagen binding, presumably by binding to an overlapping epitope on collagen. This has significant implications for the use of saratin as a tool to inhibit platelet-collagen interactions.
Comparative Immunogenicities of Chikungunya Vaccines Prepared in Avian and Mammalian Tissues (1967)

SummaryThe comparative immunogenicities of experimental formalin-inactivated chikungunya (CHIK) vaccines prepared in chick-embryo (CE), suckling-mouse-brain (SMB), and green-monkey kidney-cell (GMKC) tissue culture with the CHIK 168 virus have been described. Tests of protection in mice revealed that CE vaccine was markedly inferior to either SMB or GMKC vaccine. Both SMB and GMKC vaccine were highly effective in protecting mice against an intracerebral challenge. However, the potentially encephalitogenic properties of SMB vaccines seriously limit their use in practice, so further evaluation of this vaccine was not now pursued. Results of plaque-inhibition tests revealed that GMKC vaccine elicited significant levels of serum-neutralization (N) antibody in mice to heterologous African E-103, Asian BAH-306, and Indian C-266 strains as well as the homologous 168 strain of CHIK virus. To correlate these findings with actual protection a vaccine trial was performed in rhesus monkeys, with these strains of the CHIK virus in the challenge procedure. After three doses of GMKC vaccine, high levels of N antibody developed in monkeys, and in most instances, CF and HI antibody were present in low titers to the challenge viruses. The immunogenic potency of GMKC vaccine was clearly defined by the complete absence of viremia in the vaccinated monkeys and no appreciable stimulation of N, complement-fixation, or hemagglutination-inhibition antibody subsequent to challenge. In contrast, the control monkeys, with one exception, had viremia, and responded with high levels of N, CF, and HI antibody after challenge.
Development of a low-cost fall intervention system for hospitalized dementia patients (2012)

The current state of the art approach to preventing falls of hospitalized elderly adults with dementia is to use a video surveillance setup in each of the hospital rooms and have hospital personnel continuously monitor the video feeds. In this research, we are developing a motion monitoring system to reduce the number of accidental falls among patients at acute risk, while preserving their privacy. The prototypical system includes five accelerometer-based wireless sensors that are placed on the wrists, ankles, and chest of a patient. The system senses the movements and postures of the patient and transmits the information wirelessly to a remote base station. The received motion information is processed in real-time and used to animate a 3D avatar that figuratively represents the movements of the patient. The 3D avatar is intended to give care staff early warning of patient wakefulness, agitation, and of patients attempt to arise from the bed without assistance, while preserving the privacy of the patients. This research also aims to develop predicative algorithms to detect fall-antecedent activity and provide an early warning to care personnel. The base station keeps the captured video and the received motion information synchronized in time and stores them together into a database. The stored video and motion information can be played back in time to plot the motion information as real-time signals on a screen that is synchronized with the captured video of the patient. This paper provides background, motivation, and current state of the art approaches to reducing falls in hospitals. Our prototypical system has undergone preliminary testing successfully on several elderly patients at William Beaumont Hospital at Royal Oak, MI, USA.
Testing configurable LUT-based FPGA's (1998)

We present a new technique for testing field programmable gate arrays (FPGA's) based on look-up tables (LUT's). We consider a generalized structure for the basic FPGA logic element (cell); it includes devices such as LUT's, sequential elements (flip-flops), multiplexers and control circuitry. We use a hybrid fault model for these devices. The model is based on a physical as well as a behavioral characterization. This permits detection of all single faults (either stuck-at or functional) and some multiple faults using repeated FPGA reprogramming. We show that different arrangements of disjoint one-dimensional (l-D) cell arrays with cascaded horizontal connections and common vertical input lines provide a good logic testing regimen. The testing time is independent of the number of cells in the array (C-testability), We define new conditions for C-testability of programmable/reconfigurable arrays. These conditions do not suffer from limited I/O pins. Cell configuration affects the controllability/observability of the iterative array. We apply the approach to various Xilinx FPGA families and compare it to prior work.
Endogenous Digoxin-Immunoreactive Substance in Human Pregnancies* (1984)

We report the presence of an immunoreactive digoxin-like substance in blood from third trimester pregnant women. The sera from 51 women in the third trimester of pregnancy were analyzed by 4 commercially available digoxin RIAs. None of these patients was receiving digoxin. Digoxin immunoreactivity was detected in all patients by 3 of 4 assays. The measured values, in nanograms per ml digoxin equivalent, were (mean +/- SD): method A, 0.27 +/- 0.05; method B, 0.28 +/- 0.07; method C, 0.01 +/- 0.01; and method D, 0.15 +/- 0.06. Method B measured values greater than 0.50 ng/ml in sera from 5 patients. Digoxin immunoactivity was not detectable 24 h postpartum, suggesting a half-life in serum of 6 h or less. Exogenous digoxin added to these serum samples resulted in quantitatively additive increments above the endogenous measured levels. Three of 4 digoxin RIAs did not distinguish between true digoxin and the endogenous substance present in the sera of third-trimester pregnant patients. Preliminary evidence suggests that the endogenous digoxin immunoactivity is not due to elevation of levels of major known steroids in the blood of these women. Clinical management of women requiring digoxin therapy during pregnancy, therefore, is complicated by the inability to assume the same therapeutic range of digoxin in serum during the third trimester of pregnancy as in adult nonpregnant individuals.
Pattern-based Runtime Management of Composite Cloud Applications (2013)

The management of composite Cloud applications is a challenging problem as current available technologies provide management solutions that are tightly coupled to individual applications. Reusing and transferring management knowledge from one application to another in an automated way is a major issue. In this paper, we present a pattern-based approach which enables the decoupling of high level and low level management knowledge and show how both can be applied together fully automated to various kinds of applications.
Highly Sensitive, Transparent, and Durable Pressure Sensors Based on Sea‐Urchin Shaped Metal Nanoparticles (2016)

Highly sensitive, transparent, and durable pressure sensors are fabricated using sea-urchin-shaped metal nanoparticles and insulating polyurethane elastomer. The pressure sensors exhibit outstanding sensitivity (2.46 kPa<sup>-1</sup> ), superior optical transmittance (84.8% at 550 nm), fast response/relaxation time (30 ms), and excellent operational durability. In addition, the pressure sensors successfully detect minute movements of human muscles.
Prostate Cancer Localization Using Multiparametric MR Imaging: Comparison of Prostate Imaging Reporting and Data System (PI-RADS) and Likert Scales (2013)

http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.13122233/-/DC1.
The Employment of Sodium Hydride as a Condensing Agent (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Employment of Sodium Hydride as a Condensing AgentNathan Green and F. B. LaForgeCite this: J. Am. Chem. Soc. 1948, 70, 6, 2287–2288Publication Date (Print):June 1, 1948Publication History Published online1 May 2002Published inissue 1 June 1948https://doi.org/10.1021/ja01186a508RIGHTS & PERMISSIONSArticle Views120Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (290 KB) Get e-Alertsclose Get e-Alerts
Method-level code clone detection through LWH (Light Weight Hybrid) approach (2014)

Many researchers have investigated different techniques to automatically detect duplicate code in programs exceeding thousand lines of code. These techniques have limitations in finding either the structural or functional clones. We propose a LWH (Light Weight Hybrid) approach combining textual analysis and metrics for the detection of method-level syntactic and semantic clones in C and Java projects. This approach has been experimenting for the detection of all four types of clones by a specific set of metrics assessment and textual comparison. A tool named CloneManager has been developed in Java to support the experiments carried out and to validate the proposed approach. A benchmark dataset widely referred in the literature and medium to large size open-source projects developed in C or Java. Java is used for the experiments. The results show that the proposed approach is able to detect all four types of clones accurately with the precision and recall values ranging from 88% to 100%.
SUPERFAMILY—sophisticated comparative genomics, data mining, visualization and phylogeny (2008)

SUPERFAMILY provides structural, functional and evolutionary information for proteins from all completely sequenced genomes, and large sequence collections such as UniProt. Protein domain assignments for over 900 genomes are included in the database, which can be accessed at http://supfam.org/. Hidden Markov models based on Structural Classification of Proteins (SCOP) domain definitions at the superfamily level are used to provide structural annotation. We recently produced a new model library based on SCOP 1.73. Family level assignments are also available. From the web site users can submit sequences for SCOP domain classification; search for keywords such as superfamilies, families, organism names, models and sequence identifiers; find over- and underrepresented families or superfamilies within a genome relative to other genomes or groups of genomes; compare domain architectures across selections of genomes and finally build multiple sequence alignments between Protein Data Bank (PDB), genomic and custom sequences. Recent extensions to the database include InterPro abstracts and Gene Ontology terms for superfamiles, taxonomic visualization of the distribution of families across the tree of life, searches for functionally similar domain architectures and phylogenetic trees. The database, models and associated scripts are available for download from the ftp site.
La politique de la montagne Rapport d'évaluation, Gilles Bazin et al (2025)

Kroll Jean-Christophe. La politique de la montagne Rapport d'évaluation, Gilles Bazin et al. In: Économie rurale. N°257, 2000. pp. 99-100.
Fast Parzen density estimation using clustering-based branch and bound (1994)

This correspondence proposes a fast Parzen density estimation algorithm that would be especially useful in nonparametric discriminant analysis problems. By preclustering the data and applying a simple branch and bound procedure to the clusters, significant numbers of data samples that would contribute little to the density estimate can be excluded without detriment to actual evaluation via the kernel functions. This technique is especially helpful in the multivariant case, and does not require a uniform sampling grid. The proposed algorithm may also be used in conjunction with the data reduction technique of Fukunaga and Hayes (1989) to further reduce the computational load. Experimental results are presented to verify the effectiveness of this algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>