gebhart/patrepeval huggingface dataset:
Decarboxylation of α-(Benzenesulfonamido)-carboxylic Acids (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDecarboxylation of α-(Benzenesulfonamido)-carboxylic AcidsRichard H. Wiley and N. R. SmithCite this: J. Am. Chem. Soc. 1951, 73, 10, 4719–4720Publication Date (Print):October 1, 1951Publication History Published online1 May 2002Published inissue 1 October 1951https://pubs.acs.org/doi/10.1021/ja01154a069https://doi.org/10.1021/ja01154a069research-articleACS PublicationsRequest reuse permissionsArticle Views94Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Analytical investigation of supersonic turbomachinery blading. 2 - Analysis of impulse turbine-blade sections (1968)

Surface Mach numbers, inlet flow angle, and specific heat ratio effects on geometric features of supersonic impulse turbine blade sections in Mach range 1.5 to 5.0
Detection of bacterial contamination in prestorage culture‐negative apheresis platelets on day of issue with the Pan Genera Detection test (2011)

The PGD test detected bacterial contamination in 1:3069 (9 of 27,620) doses released as negative by prestorage culture in PLTs as young as 3 days old. Three contaminated doses, two clinically insignificant, had nonreactive PGD tests, while 0.51% of tests were false positives. Application of this test on day of issue can interdict contaminated units and prevent transfusion reactions.
Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE (2010)

Compared with previous years, the reported number of ART cycles in Europe has increased, pregnancy rates have increased marginally, even though fewer embryos were transferred and the multiple delivery rates have declined.
Methods of Plant Transformation- A Review (2018)

Plant transformation is now a core research tool in plant biology and a practical tool for transgenic plant development. There are many verified methods for stable introduction of novel genes into the nuclear genomes of diverse plant species. As a result, gene transfer and regeneration of transgenic plants are no longer the factors limiting the development and application of practical transformation systems for many plant species. However, the desire for higher transformation efficiency has stimulated work on not only improving various existing methods but also in inventing novel methods. The most published techniques for gene transfer into plant cells were dismissed as either disproven or impractical for use in routine production of transgenic plants. In many laboratories, virtually all the transformation work relies on particle bombardment with DNA coated microprojectiles or Agrobacterium mediated transformation for gene transfer to produce transgenic plants from a range of plant species.
Novel Noncompetitive IL-1 Receptor–Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth (2015)

Preterm birth (PTB) is firmly linked to inflammation regardless of the presence of infection. Proinflammatory cytokines, including IL-1β, are produced in gestational tissues and can locally upregulate uterine activation proteins. Premature activation of the uterus by inflammation may lead to PTB, and IL-1 has been identified as a key inducer of this condition. However, all currently available IL-1 inhibitors are large molecules that exhibit competitive antagonism properties by inhibiting all IL-1R signaling, including transcription factor NF-κB, which conveys important physiological roles. We hereby demonstrate the efficacy of a small noncompetitive (all-d peptide) IL-1R-biased ligand, termed rytvela (labeled 101.10) in delaying IL-1β-, TLR2-, and TLR4-induced PTB in mice. The 101.10 acts without significant inhibition of NF-κB, and instead selectively inhibits IL-1R downstream stress-associated protein kinases/transcription factor c-jun and Rho GTPase/Rho-associated coiled-coil-containing protein kinase signaling pathways. The 101.10 is effective at decreasing proinflammatory and/or prolabor genes in myometrium tissue and circulating leukocytes in all PTB models independently of NF-κB, undermining NF-κB role in preterm labor. In this work, biased signaling modulation of IL-1R by 101.10 uncovers a novel strategy to prevent PTB without inhibiting NF-κB.
Enniatin Production by<i>Fusarium tricinctum</i>and its Effect on Germinating Wheat Seeds (1987)

Fusarium tricinctum strains isolated from winter wheat with symptoms of crown and root rot, English ivy with leaf spot, apparently healthy red clover root, or pasture soil produced enniatins. Although enniatins are metabolites of at least five other species in the genus, this is the first report of their production by F. tricinctum. Analysis by mass spectrometry/mass spectrometry of extracts from 13 isolates showed that 10 of them were positive for enniatin with concentrations ranging from about 3 to 3.270 .mu.g/g of corn substrate. When enniatin (10-80 .mu.g/ml) was added to the solution in which wheat seeds were germinated, growth reduction of the developing seeds was directly related to the concenrated of enniatin, with root elongation being inhibited more than leaf development.
GERIATRIC CLINICAL PLACEMENTS (1989)

Recognizing that the profession must prepare individuals able and willing to work with the elderly, educators must consider the long-term care facility and geriatric clinical placement as part of the basic nursing curriculum. Data presented indicate that the geriatric clinical placement offers students opportunities to learn and practice a wide range of nursing skills and suggest that the long-term care facility is a valuable, underused clinical resource for intermediate and advanced students.
Cholesterol-Lowering Effects of Maitake (Grifola frondosa) Fiber, Shiitake (Lentinus edodes) Fiber, and Enokitake (Flammulina velutipes) Fiber in Rats (2001)

The effects of mushroom fibers on serum cholesterol and hepatic low-density lipoprotein (LDL) receptor mRNA in rats were investigated. Rats were fed a cholesterol-free diet with 50 g/kg cellulose powder (CP), 50 g/kg maitake (Grifola frondosa) fiber (MAF), 50 g/kg shiitake (Lentinus edodes) fiber (SF), or 50 g/kg enokitake (Flammulina velutipes) fiber (EF) for 4 weeks. There were no significant differences in the body weight, food intake, liver weight, cecum weight, and cecum pH among the groups. Cecal acetic acid, butyric acid, and total short-chain fatty acid (SCFA) concentrations in the SF and EF groups were significantly higher than those in the other groups. The serum total cholesterol concentration in the CP group was significantly higher than that in the MAF and EF groups. The very LDL (VLDL) + intermediate-density lipoprotein (IDL) + LDL-cholesterol concentration in the CP group was significantly higher than that in the MAF, SF, and EF groups, whereas the high-density lipoprotein (HDL)-cholesterol concentration in the EF group was significantly lower than that in the other groups at the end of the 4-week feeding period. The hepatic LDL receptor mRNA level in the EF group was significantly higher than that in the CP group. The fecal cholesterol excretion in the MAF, SF, and EF groups was significantly higher than that in the CP group. The results of this study demonstrate that MAF and EF lowered the serum total cholesterol level by enhancement of fecal cholesterol excretion, and in particular, by enhancement of hepatic LDL receptor mRNA in EF group.
Fabrication of a Graded-Index Circular-Core Polymer Parallel Optical Waveguide Using a Microdispenser for a High-Density Optical Printed Circuit Board (2012)

A simple fabrication method for multimode polymer optical waveguides with graded-index (GI) circular cores is introduced for use in optical printed circuit boards (O-PCBs). The new method, named “Mosquito method,” utilizes a microdispenser to dispense a viscous monomer directly onto the substrates. By optimizing the dispensing conditions, 12-channel parallel waveguides with circular GI-cores (core diameter of 40 μm) are successfully fabricated using the Mosquito method. The advantages of GI-core waveguides for O-PCB applications are discussed by comparing the optical characteristics of the fabricated waveguides with those of conventional step-index (SI) square-core polymer waveguides, and even with those of silica-based GI multimode fibers (MMFs), as an ideal case. To the best of our knowledge, this is the first comparison of SI- and GI-core multimode polymer waveguides that are composed of the same polymer materials and that have similar core and pitch sizes. We experimentally demonstrate that the GI circular-core polymer waveguides fabricated by the Mosquito method have sufficiently low propagation loss (0.033 dB/cm at 850 nm), low connection loss with GI-MMFs, and low interchannel crosstalk. We observe approximately -50 dB of interchannel crosstalk in the 250-μm pitch GI-core waveguide fabricated, which is almost 10 dB lower than in the SI counterpart. Furthermore, sufficiently low crosstalk is maintained in a half-pitch GI-core waveguide fabricated by the Mosquito method.
Enzymatic Reduction of Arsenic Compounds in Mammalian Systems:  The Rate-Limiting Enzyme of Rabbit Liver Arsenic Biotransformation Is MMA<sup>V</sup> Reductase (1999)

A unique enzyme, MMA(V) reductase, has been partially purified from rabbit liver by using DEAE-cellulose, carboxymethylcellulose, and red dye ligand chromatography. The enzyme is unique since it is the rate-limiting enzyme in the biotransformation of inorganic arsenite in rabbit liver. The K(m) and V(max) values were 2.16 x 10(-)(3) M and 10.3 micromol h(-)(1) (mg of protein)(-)(1). When DMA(V) or arsenate was tested as a substrate, the K(m) was 20.9 x 10(-)(3) or 109 x 10(-)(3) M, respectively. The enzyme has an absolute requirement for GSH. Other thiols such as DTT or L-cysteine were inactive alone. At a pH below the physiological pH, GSH carried out this reduction, but this GSH reduction in the absence of the enzyme had little if any value at pH 7.4. When the K(m) values of rabbit liver arsenite methyltransferase (5.5 x 10(-)(6) M) and MMA(III) methyltransferase (9.2 x 10(-)(6)) were compared to that of MMA(V) reductase (2.16 x 10(-)(3) M), it can be concluded that MMA(V) reductase was the rate-limiting enzyme of inorganic arsenite biotransformation. MMA(V) reductase was also present in surgically removed human liver.
Association of a 85-kDa Serine Kinase with Activated Fibroblast Growth Factor Receptor-4 (1996)

Fibroblast growth factors (FGFs) transduce a variety of biological signals via four distinct tyrosine kinase receptors. We have characterized the phosphorylation of FGF receptor 4 (FGFR-4) and its association with a putative substrate, p85, using transfected L6 myoblast and NIH3T3 fibroblast cell lines. FGFR-4 was phosphorylated in vivo and in vitro mainly on serine and threonine residues in several peptides and to a lower degree on tyrosine residues. When analyzed further by in-gel kinase assay, immunoprecipitates of ligand-activated FGFR-4 contained a serine autophosphorylated polypeptide doublet of 85 kDa. Analysis of the major autophosphorylation site Y754F mutant of FGFR-4 showed that binding of p85 and its serine phosphorylation were independent of receptor autophosphorylation at this site. Okadaic acid treatment increased the basal autophosphorylation activity of p85 but decreased FGFR-4 tyrosine phosphorylation. In contrast, orthovanadate treatment increased the tyrosine phosphorylation of FGFR-4. These data show that a serine kinase is associated with activated FGFR-4 and suggest a role for serine phosphorylation in FGFR-4 function.
[Microarray DNA chip in analyzing the association between HLA-DRB and advanced hepatosplenic schistosomiasis]. (2005)

Allele HLA-DRB1*04x is positively, while HLA-DRB1*15x is negatively, correlated with advanced hepatosplenic schistosomiasis.
A Frames Approach to Semantic Analysis (2012)

Abstract This chapter contrasts a broad use of the term frame in cognitive science with its related use in a type of linguistic analysis, describing the principles and data structure of a particular research project (FrameNet) as a model for representing frame-based analyses of lexical meanings. It introduces an extension of the project to include the semantic contributions of grammatical constructions and concludes by surveying the implications of a frames perspective on some familiar issues in linguistic semantics.
3D through-wall imaging with unmanned aerial vehicles using wifi (2017)

In this paper, we are interested in the 3D through-wall imaging of a completely unknown area, using WiFi RSSI and Unmanned Aerial Vehicles (UAVs) that move outside of the area of interest to collect WiFi measurements. It is challenging to estimate a volume represented by an extremely high number of voxels with a small number of measurements. Yet many applications are time-critical and/or limited on resources, precluding extensive measurement collection. In this paper, we then propose an approach based on Markov random field modeling, loopy belief propagation, and sparse signal processing for 3D imaging based on wireless power measurements. Furthermore, we show how to design efficient aerial routes that are informative for 3D imaging. Finally, we design and implement a complete experimental testbed and show high-quality 3D robotic through-wall imaging of unknown areas with less than 4% of measurements.
Surface and Sub-surface Characteristics of Metal-Bond / ELID and Resin-bond Diamond Ground Single Crystal Silicon (2003)

紙本
Merlin (2009)

The last several years have seen a proliferation of static and runtime analysis tools for finding security violations that are caused by explicit information flow in programs. Much of this interest has been caused by the increase in the number of vulnerabilities such as cross-site scripting and SQL injection. In fact, these explicit information flow vulnerabilities commonly found in Web applications now outnumber vulnerabilities such as buffer overruns common in type-unsafe languages such as C and C++. Tools checking for these vulnerabilities require a specification to operate. In most cases the task of providing such a specification is delegated to the user. Moreover, the efficacy of these tools is only as good as the specification. Unfortunately, writing a comprehensive specification presents a major challenge: parts of the specification are easy to miss, leading to missed vulnerabilities; similarly, incorrect specifications may lead to false positives. This paper proposes Merlin, a new approach for automatically inferring explicit information flow specifications from program code. Such specifications greatly reduce manual labor, and enhance the quality of results, while using tools that check for security violations caused by explicit information flow. Beginning with a data propagation graph, which represents interprocedural flow of information in the program, Merlin aims to automatically infer an information flow specification. Merlin models information flow paths in the propagation graph using probabilistic constraints. A naive modeling requires an exponential number of constraints, one per path in the propagation graph. For scalability, we approximate these path constraints using constraints on chosen triples of nodes, resulting in a cubic number of constraints. We characterize this approximation as a probabilistic abstraction, using the theory of probabilistic refinement developed by McIver and Morgan. We solve the resulting system of probabilistic constraints using factor graphs, which are a well-known structure for performing probabilistic inference. We experimentally validate the Merlin approach by applying it to 10 large business-critical Web applications that have been analyzed with CAT.NET, a state-of-the-art static analysis tool for .NET. We find a total of 167 new confirmed specifications, which result in a total of 322 additional vulnerabilities across the 10 benchmarks. More accurate specifications also reduce the false positive rate: in our experiments, Merlin-inferred specifications result in 13 false positives being removed; this constitutes a 15% reduction in the CAT.NET false positive rate on these 10 programs. The final false positive rate for CAT.NET after applying Merlin in our experiments drops to under 1%.
Modified Recombinant Proteins Can Be Exported via the Sec Pathway in Escherichia coli (2012)

The correct folding of a protein is a pre-requirement for its proper posttranslational modification. The Escherichia coli Sec pathway, in which preproteins, in an unfolded, translocation-competent state, are rapidly secreted across the cytoplasmic membrane, is commonly assumed to be unfavorable for their modification in the cytosol. Whether posttranslationally modified recombinant preproteins can be efficiently transported via the Sec pathway, however, remains unclear. ACP and BCCP domain (BCCP87) are carrier proteins that can be converted into active phosphopantetheinylated ACP (holo-ACP) and biotinylated-BCCP (holo-BCCP) by AcpS and BirA, respectively. In the present study, we show that, when ACP or BCCP87 is fused to the C-terminus of secretory protein YebF or MBP, the resulting fusion protein preYebF-ACP, preYebF-BCCP87, preMBP-ACP or preMBP-BCCP87 can be modified and then secreted. Our data demonstrate that posttranslational modification of preYebF-ACP, preYebF-BCCP87 preMBP-ACP and preMBP-BCCP87 can take place in the cytosol prior to translocation, and the Sec machinery accommodates these previously modified fusion proteins. High levels of active holo-ACP and holo-BCCP87 are achieved when AcpS or BirA is co-expressed, especially when sodium azide is used to retard their translocation across the inner membrane. Our results also provide an alternative to achieve a high level of modified recombinant proteins expressed extracellularly.
Impact of Si substrate orientations on electrical properties of crystalline Gd2O3 thin films for high-K application (2006)

The authors compare the properties of epitaxial Gd2O3 thin films grown on silicon substrates with three different orientations for high-K application. Pt∕Gd2O3∕Si(111) and Pt∕Gd2O3∕Si(110) metal oxide semiconductor heterostructures show promising electrical properties and hence, could be considered for future generation of complementary metal oxide semiconductor devices. Capacitance equivalent oxide thicknesses estimated from capacitance versus voltage characteristics are 0.97, 1.12, and 0.93nm for the films grown on Si(001), Si(111), and Si(110) substrates, respectively. The films exhibit good insulating property with leakage current densities of 0.4, 0.5, and 4.5mA∕cm2, respectively, at (Vg−VFBV)=−1V.
An output encoding problem and a solution technique (1999)

We present a new output-encoding problem as follows. We are given a specification table, such as a truth table or a finite state machine (FSM) state table, where some of the outputs are specified in terms of ones, zeroes, and don't cares, and others are specified symbolically. The number of bits for encoding the output symbols may also be specified. We have to determine a binary code for each symbol of the symbolically specified output column such that the total number of output functions to be implemented after encoding the symbolic outputs and compacting the output columns is minimum. In this paper, we develop an exact algorithm to solve the above problem, analyze the worst case time complexity of the algorithm, and present experimental data to validate the claim that our encoding strategy helps to reduce the area of a synthesized circuit. In addition, we have investigated the possibility of using simple logical combinations of the already specified output columns to facilitate further reduction in the number of output functions.
Dynamic pronunciation models for automatic speech recognition (1999)

As of this writing, the automatic recognition of spontaneous speech by computer is fraught with errors; many systems transcribe one out of every three to five words incorrectly, whereas humans can transcribe spontaneous speech with one error in twenty words or better. This high error rate is due in part to the poor modeling of pronunciations within spontaneous speech. This dissertation examines how pronunciations vary in this speaking style, and how speaking rate and word predictability can be used to predict when greater pronunciation variation can be expected. It includes an investigation of the relationship between speaking rate, word predictability, pronunciations, and errors made by speech recognition systems. The results of these studies suggest that for spontaneous speech, it may be appropriate to build models for syllables and words that can dynamically change the pronunciations used in the speech recognizer based on the extended context (including surrounding words, phones, speaking rate, etc.). Implementation of new pronunciation models automatically derived from data within the ICSI speech recognition system has shown a 4-5% relative improvement on the Broadcast News recognition task. Roughly two thirds of these gains can be attributed to static baseform improvements; adding the ability to dynamically adjust pronunciations within the recognizer provides the other third of the improvement. The Broadcast News task also allows for comparison of performance on different styles of speech: the new pronunciation models do not help for pre-planned speech, but they provide a significant gain for spontaneous speech. Not only do the automatically learned pronunciation models capture some of the linguistic variation due to the speaking style, but they also represent vari...