gebhart/patrepeval huggingface dataset:
<i>Helicobacter pylori</i>Persistence: an Overview of Interactions between<i>H. pylori</i>and Host Immune Defenses (2006)

Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of the global human population. In order to successfully colonize the human stomach, H. pylori must initially overcome multiple innate host defenses. Remarkably, H. pylori can persistently colonize the stomach for decades or an entire lifetime despite development of an acquired immune response. This review focuses on the immune response to H. pylori and the mechanisms by which H. pylori resists immune clearance. Three main sections of the review are devoted to (i) analysis of the immune response to H. pylori in humans, (ii) analysis of interactions of H. pylori with host immune defenses in animal models, and (iii) interactions of H. pylori with immune cells in vitro. The topics addressed in this review are important for understanding how H. pylori resists immune clearance and also are relevant for understanding the pathogenesis of diseases caused by H. pylori (peptic ulcer disease, gastric adenocarcinoma, and gastric lymphoma).
SELECTION OF SWEET PEPPER (CAPSICUM ANNUUM L.) GENOTYPES FOR PARTHENOCARPIC FRUIT GROWTH (2007)

ISHS XXVII International Horticultural Congress - IHC2006: International Symposium on Advances in Environmental Control, Automation and Cultivation Systems for Sustainable, High-Quality Crop Production under Protected Cultivation SELECTION OF SWEET PEPPER (CAPSICUM ANNUUM L.) GENOTYPES FOR PARTHENOCARPIC FRUIT GROWTH
Minutes of the Council (1958)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
ChemInform Abstract: SIMULTANEOUS PREPARATION OF ETHYLENE OXIDE AND PROPYLENE OXIDE BY THE HYDROPEROXIDE EPOXIDATION OF OLEFINS (1976)

Abstract Zur Umgehung der Schwierigkeiten einer direkten Epoxidierung von Äthylen (I) mit Hydroperoxiden wird ein technisches Verfahren zur gemeinsamen Darstellung von Äthylenoxid (III) und Propylenoxid (IV) ausgehendl von Äthylen‐(I)‐Propylen‐(II)‐Gemischen vorgeschlagen.
Gene-Enzyme Relations in Histidine Biosynthesis in Yeast (1964)

Each of the histidine mutants of Saccharomyces cerevisiae has been correlated with a particular step in histidine biosynthesis. The relations of the genes controlling histidine biosynthesis in yeast appear to be identical with those found in Neurospora and clearly distinct from those found in Salmonella.
Under Blue Blankets (2014)

You’re straight, right? says a lean black man in a Subway on Mass Ave by the Orange Line stop as you fill up a cup with ice and Sprite.
QT prolongation in anaesthetized guinea‐pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates (2004)

Many non-cardiovascular drugs can prolong the QT interval of the electrocardiogram (ECG); this is an accessory property not necessary for their pharmacological action and generally linked to the block of the potassium HERG channels and delayed cardiac repolarization. The QT prolongation can lead to a dangerous tachyarrhythmia, called torsade de pointes, and potentially to fatal ventricular fibrillation. The experimental approaches, aimed at an early identification of this undesidered property, often require sophisticated and expensive equipment or the use of superior animal species (dog, primates) that cannot be employed easily for ethical and/or economic reasons. This work aimed to study drug-induced QT prolongation in anaesthetized guinea-pigs and to evaluate the reliability of such an experimental approach to obtain a satisfying predictive parameter of the torsadogenicity of drugs in humans. Seven drugs that were torsadogenic in humans (astemizole, cisapride, haloperidol, quinidine, sotalol, terfenadine and thioridazine) and two that were non-torsadogenic (chlorprotixene and diazepam) were administered i.v. to guinea-pigs under pentobarbital anaesthesia. The ECGs were recorded by four electrodes inserted in the subcutaneous layer of the limbs. Both RR and QT intervals were measured in Leads II and III and then the correct QT values were calculated by Bazett and Fridericia algorithms (QTcB and QTcF, respectively). All the drugs, with the exception of chlorprotixene and diazepam, produced a dose-dependent prolongation of the QT and RR intervals and a significant increase of QTcB and QTcF values. It can be concluded that this method represents a rapid and low-cost procedure to evaluate the cardiac safety pro fi le in the preliminary screening of a high number of drugs or drug candidates.
Few-mode fiber based optical sensors (2015)

Few-mode fibers (FMFs) have found applications in optical communications and sensors with attractive features that standard single mode fiber (SSMF) do not possess. We report our recent progress on FMF based optical sensors, and show the potential of utilizing the spatial dimension for multi-parameter sensing with discrimination capability. We first show a discrete type FMF sensor based on interferometer structure with a short FMF, utilizing the modal interference between either the polarizations (x and y) or the spatial modes (LP(01) and LP(11)). We then show a distributed type FMF sensor by generating the stimulated Brillouin scattering (SBS) in a long FMF. We characterize the Brillouin gain spectrum (BGS) with a pump-probe configuration, and measure the temperature and strain coefficients for LP(01) and LP(11) modes. The proposed FMF based optical sensor can be applied to sensing a wide range of parameters.
Intermediate-band solar cells: Influence of band formation on dynamical processes in InAs/GaAs quantum dot arrays (2010)

We present a theoretical model for design and analysis of semiconductor quantum dot (QD) array-based intermediate-band solar cell (IBSC). The plane-wave method with periodic boundary conditions is used in expansion of the $\mathbf{k}\ensuremath{\cdot}\mathbf{p}$ Hamiltonian for calculation of the electronic and optical structures of InAs/GaAs QD array. Taking into account realistic QD shape, QD periodicity in the array, as well as effects such as band mixing between states in the conduction and valence band, strain and piezoelectric field, the model reveals the origin of the intermediate-band formation inside forbidden energy gap of the barrier material. Having established the interrelation between QD periodicity and the electronic structure across the QD array Brillouin zone, conditions are identified for the appearance of pure zero density-of-states regions, that separate intermediate band from the rest of the conduction band. For one realistic QD array we have estimated all important absorption coefficients in IBSC, and most important, radiative and nonradiative scattering times. Under radiative-limit approximation we have estimated efficiency of such IBSC to be 39%.
Safety assessment of genetically modified foods. (2003)

The development of novel foods produced through agricultural biotechnology is a complex three-stage process: gene discovery, line selection, and product advancement to commercialization. The safety of genetically modified foods is an integral part of the overall developmental process throughout all of the stages. In the discovery stage, the safety of the gene, its source, and the gene products must be considered. If any questions arise at this stage, these questions must be answered later in the developmental process. During the line selection stage, the genetically modified seed progresses through a variety of greenhouse and field trials. At this stage, the biological and agronomic equivalence of the genetically modified crop to its traditional counterpart must be compared. While the evaluations made during this stage are not specifically directed toward a safety assessment, many potential products with unusual characteristics are eliminated during this stage of development. However, the elimination of products with unusual agronomic or biological characteristics enhances the likelihood that a safe product will be generated. Finally, in the pre-commercialization stage, the genetically modified product undergoes a detailed safety assessment process. This process focuses on the safety of the gene products associated with the introduced gene and any other likely toxicological or anti-nutrient factors associated with the source of the novel gene and the crop to which it was introduced. The safety of the genetically modified product for both food and feed uses is considered. Thus far, all of the genetically modified products brought into the marketplace have been subjected to such an intensive safety assessment. The safety assessment data have been reviewed by regulatory authorities around the world. The current generation of genetically modified products are quite safe for human and feed animal consumption.
Response of patients in mixed state of anxiety and depression to low dose sulpiride. (1993)

Two cases with mixed symptoms of anxiety and depression are described. In both cases, a low dose of sulpiride was effective, improving patients anxious and depressive symptoms without severe side effects. These findings suggest that a low dose sulpiride treatment can be useful in the treatment of anxious and depressive patients.
Predicting permeability and gas production of hydraulically fractured tight sands from microseismic data (2010)

Abstract The main objective of hydraulic well stimulation is creating fractures in a tight rock that enhance its natural permeability and make hydrocarbon production economic. Because the geometry of fractures and the permeability of treated formation influence the subsequent production, their assessment is important for the development of tight-gas fields. The fracture shapes and orientations are inferred conventionally from microseismic data acquired in the process of well stimulation, but the same data also can be used to estimate the formation permeability. We have compared two techniques for permeability estimation that utilize different aspects of information contained in the observed microseismicity. We applied those techniques to data recorded in the course of the hydraulic fracturing of four wells drilled in the Pinedale Field, Wyoming, U.S.A. Then we used the obtained permeabilities to predict the gas rates from 20 treatment stages at which the number of identified microseismic events was sufficient to perform our analysis. The predictions of both techniques correlate with production and allow us to establish the characteristics of rocks and hydraulic fractures that make good producers at Pinedale.
Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans (2002)

Hyperglycemia acutely increases circulating cytokine concentrations by an oxidative mechanism, and this effect is more pronounced in subjects with IGT. This suggests a causal role for hyperglycemia in the immune activation of diabetes.
People Counting and Human Detection in a Challenging Situation (2010)

Reliable people counting and human detection is an important problem in visual surveillance. In recent years, the field has seen many advances, but the solutions have restrictions: people must be moving, the background must be simple, and the image resolution must be high. This paper aims to develop an effective method for estimating the number of people and locate each individual in a low resolution image with complicated scenes. The contribution of this paper is threefold. First, postprocessing steps are performed on background subtraction results to estimate the number of people in a complicated scene, which includes people who are moving only slightly. Second, an Expectation Maximization (EM)-based method has been developed to locate individuals in a low resolution scene. In this method, a new cluster model is used to represent each person in the scene. The method does not require a very accurate foreground contour. Third, the number of people is used as a priori for locating individuals based on feature points. Hence, the methods for estimating the number of people and for locating individuals are connected. The developed methods have been validated based on a 4-hour video, with the number of people in the scene ranging from 36 to 222. The best result for estimating the number of people has an average error of 10% over 51 test cases. Based on the estimated number of people, some results of the EM-based method have also been shown.
Anterior Cervical Fusion and Caspar Plate Stabilization for Cervical Trauma (1989)

Abstract A technique for anterior cervical iliac graft fusion with standardized, commercially available screw and plate fixation (Caspar plating) has been developed. The step-by-step procedure, as well as the instruments designed to facilitate the procedure, are described in this report. Sixty cases of cervical trauma (fractures, subluxations, ligamentous instability, or a combination of these problems) were treated with Caspar plating. All patients obtained fusion, and stability was achieved immediately after surgery without external stabilization. No unusual surgical complications occurred, and the most dreaded complication of dural penetration by drilling or screw placement was not observed. This report details the neurological presentation, anatomical lesions, surgical therapy, and outcome of these patients. Caspar plating combines the advantage of an anterior surgical approach with immediate postoperative stabilization without external stabilization. This advantage persists even in the presence of posterior ligamentous instability. The technique is an important addition to the surgical treatment of cervical trauma.
The design of an analogue RF front end for a multi-role radio (2002)

The drive towards a software-defined radio (SDR) in which much of the processing is controlled by reprogrammable digital hardware is placing new demands on the analogue RF front end. In order to facilitate multi-role multi-mode operation, this must impose the minimum of constraints on the parameters that can be defined in software, while still offering a performance which is at least as good as today's application-specific radios. This paper outlines some of the areas of research being carried out at the University of Bristol, funded by DERA, in an attempt to improve the flexibility and performance of the analogue RF front-end of a multi-role radio.
Green Curry (2011)

Brick Lane and the surrounding area have historically attracted successive groups of migrants, one of the most prominent currently being those from the Sylhet region of Bangladesh. Following decades of economic depression and racial tension, regeneration efforts have ensured that the area is now inextricably associated with the curry restaurants that line the street. Food is the medium for Brick Lane's transformation, yet the use of food as a centerpiece for development is also ripe with ambivalence. Since the mid-1990s, local Bengali restaurateurs have held an annual Curry Festival to promote local businesses, and to help counter negative publicity. This paper examines the efforts of local restaurateurs to respond to events and to manage the Brick Lane “brand” proactively through the Curry Festival.
Involvement of peripheral artemin signaling in tongue pain (2015)

Burning mouth syndrome is characterized by altered sensory qualities, namely tongue pain hypersensitivity. We found that the mRNA expression of Artemin (Artn) in the tongue mucosa of patients with burning mouth syndrome was significantly higher than that of control subjects, and we developed a mouse model of burning mouth syndrome by application of 2,4,6-trinitrobenzene sulfonic acid (TNBS) diluted with 50% ethanol to the dorsum of the tongue. TNBS treatment to the tongue induced persistent, week-long, noninflammatory tongue pain and a significant increase in Artn expression in the tongue mucosa and marked tongue heat hyperalgesia. Following TNBS treatment, the successive administration of the transient receptor potential vanilloid 1 (TRPV1) antagonist SB366791 or neutralizing anti-Artn antibody completely inhibited the heat hyperalgesia. The number of glial cell line-derived neurotrophic factor family receptor α3 (GFRα3)-positive and TRPV1-positive trigeminal ganglion (TG) neurons innervating the tongue significantly increased following TNBS treatment and was significantly reduced by successive administration of neutralizing anti-Artn antibody. The capsaicin-induced current in TG neurons innervating the tongue was enhanced following TNBS treatment and was inhibited by local administration of neutralizing anti-Artn antibody to the tongue. These results suggest that the overexpression of Artn in the TNBS-treated tongue increases the membrane excitability of TG neurons innervating the tongue by increasing TRPV1 sensitivity, which causes heat hyperalgesia. This model may be useful for the study of tongue pain hypersensitivity associated with burning mouth syndrome.
Selective long‐term reorganization of the corticospinal projection from the supplementary motor cortex following recovery from lateral motor cortex injury (2009)

Brain injury affecting the frontal motor cortex or its descending axons often causes contralateral upper extremity paresis. Although recovery is variable, the underlying mechanisms supporting favorable motor recovery remain unclear. Because the medial wall of the cerebral hemisphere is often spared following brain injury and recent functional neuroimaging studies in patients indicate a potential role for this brain region in the recovery process, we investigated the long-term effects of isolated lateral frontal motor cortical injury on the corticospinal projection (CSP) from intact, ipsilesional supplementary motor cortex (M2). After injury to the arm region of the primary motor (M1) and lateral premotor (LPMC) cortices, upper extremity recovery is accompanied by terminal axon plasticity in the contralateral CSP but not the ipsilateral CSP from M2. Furthermore, significant contralateral plasticity occurs only in lamina VII and dorsally within lamina IX. Thus, selective intraspinal sprouting transpires in regions containing interneurons, flexor-related motor neurons, and motor neurons supplying intrinsic hand muscles, which all play important roles in mediating reaching and digit movements. After recovery, subsequent injury of M2 leads to reemergence of hand motor deficits. Considering the importance of the CSP in humans and the common occurrence of lateral frontal cortex injury, these findings suggest that spared supplementary motor cortex may serve as an important therapeutic target that should be considered when designing acute and long-term postinjury patient intervention strategies aimed to enhance the motor recovery process following lateral cortical trauma.
ChemInform Abstract: Synthesis of Isopropylidene, Benzylidene, and Related Acetals (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Multiple-frequency injection-seeded nanosecond pulsed laser without parasitic intensity modulation (2016)

Thanks to a phase-modulated injection seeder, we report the operation of a nanosecond Nd:YAG Q-switched laser with pulses having both a large spectral bandwidth and a smooth temporal waveform. Because of the smooth temporal waveform, such pulses allow, for instance, reducing the impact of the Kerr effect and, because of the large spectral bandwidth, suppressing stimulated Brillouin scattering. We conducted a parametric study of the features of the generated pulses versus the injection conditions. We show that, as opposed to the central frequency (wavelength) of the seeder, the phase modulation frequency has to be carefully chosen, but it is not a critical parameter and does not require any particular feedback.
Contextual information management using contract (2005)

In the Ambient Intelligent Computing Environment (AmI) consisting of peers (clients, servers or agents or other intelligent devices), context-awareness plays an important role to offer intelligent services for various applications, e.g., medical services, robotics, travel planning, security monitoring, and multi-player gaming. Accordingly, context management turns out to be an important issue in manipulating, acquiring information and reacting to the situation. In this paper, we describe a contract-based workflow paradigm to provide transparency and reliability of interactions among the devices and people in the AmI. This paradigm provides for software contract that captures mutual obligations using program constructs such as "require [else]" for precondition and "ensure [then]" for post condition, assertions, invariants needed in the AmI. Such program constructs are essential to deal with the uncertain nature of connectivity of ubiquitous devices and networks, and the trial-error (subjunctive) nature of the processes and the programs used in interactions among devices and people in an unpredictable environment
Towards conductive textiles: coating polymeric fibres with graphene (2017)

Conducting fibres are essential to the development of e-textiles. We demonstrate a method to make common insulating textile fibres conductive, by coating them with graphene. The resulting fibres display sheet resistance values as low as 600 Ωsq<sup>-1</sup>, demonstrating that the high conductivity of graphene is not lost when transferred to textile fibres. An extensive microscopic study of the surface of graphene-coated fibres is presented. We show that this method can be employed to textile fibres of different materials, sizes and shapes, and to different types of graphene. These graphene-based conductive fibres can be used as a platform to build integrated electronic devices directly in textiles.
A novel technique for the measurement of disruption in high‐pressure homogenization: Studies on <i>E. coli</i> containing recombinant inclusion bodies (1991)

The high-pressure homogenization of Escherichia coli, strain JM101, containing inclusion bodies of recombinant porcine somatotropin was investigated. A novel technique employing an analytical disc centrifuge was used to monitor the disruption. This a direct technique which measures cell disintegration rather than soluble protein release. The technique is particularly suited to measurements where the disruption approaches 100%. The disk centrifuge provides a size distribution of the homogenate, and furnishes evidence for the preferential disruption of larger cells. For E. coli containing inclusion bodies, and increase in the cell feed concentration from 145 g/L (wet weight) to 330 g/L resulted is poorer homogenization. Poorer disruption was also obtained by lowering the feed temperature from 20 degrees C to 5 degrees C. Only slight variations in performance were obtained by increasing the feed pH from 7.5 to 9.0 or by storing the feed at 4 degrees C for 24 h prior to disruption. Comparison with uninduced E. coli strain JM101, showed that the disruption obtained is higher for bacteria containing a recombinant inclusion body.
Osteotome Sinus Floor Elevation and Simultaneous Placement of Implants – A 1‐Year Retrospective Study with Astra Tech Implants (2007)

The OSFE technique, without bone grafts, was found to produce predictable results in the treatment of 36 patients with restricted bone volume in the posterior part of the maxilla.