gebhart/patrepeval huggingface dataset:
Ultrastructure alterations of <i>Staphylococcus aureus</i> exposed to RP59500 (1994)

Ultrastructure alterations of Staphylococcus aureus exposed to RP59500 Get access Victor Lorain, Victor Lorain The Bronx Lebanon Hospital CenterBronx, New York 10457 and the Albert Einstein College of MedicineBronx, New York, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Yves Esanu, Yves Esanu The Bronx Lebanon Hospital CenterBronx, New York 10457 and the Albert Einstein College of MedicineBronx, New York, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Leonard Amaral Leonard Amaral The Bronx Lebanon Hospital CenterBronx, New York 10457 and the Albert Einstein College of MedicineBronx, New York, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Antimicrobial Chemotherapy, Volume 33, Issue 3, March 1994, Pages 625–628, https://doi.org/10.1093/jac/33.3.625 Published: 01 March 1994 Article history Received: 30 June 1993 Accepted: 01 November 1993 Published: 01 March 1994
A design of transceiver for 13.56 MHz RFID reader using the peak detector with automatic reference voltage generator and voltage limiter (2010)

In this paper, the transceiver for RFID reader using 13.56MHz as a carrier frequency and meeting International Standard ISO 14443 type A, 14443 type B and 15693 is presented. The receiver is composed of envelope detector, VGA (Variable Gain Amplifier), low pass filter, limiter, and comparator to recovery the received signal. The proposed automatic reference voltage generator can adjust the decision level of reference voltage over the received signal amplitudes. Also, the limiter can reduce the initial settling time that affects the data latency. The transmitter is designed to meet 15693 specification. By using inductor loading circuit which can swing more than power supply and make large current even under low impedance condition, it can control modulation index from 5% to 100%t and output currents from 5 mA to 240 mA in respect of each standard. The 13.56 MHz RFID reader is implemented in 0.18 μm CMOS technology at 3.3 V single supply. The chip area excluding pads is 1.5 mm × 1.5 mm.
Thermal explosions: sub-sonic deflagration in PBX 9501 (2011)

Abstract Not Provided
Mycophenolate mofetil treatment for diffuse proliferative lupus nephritis: a multicenter clinical trial in China. (2002)

MMF in a dosage of 0.5 approximately 2.0 g/d combined with steroids is effective to control the lupus activity of DPLN and well tolerated by the patients.
B-cell-activating factor is a regulator of adipokines and a possible mediator between adipocytes and macrophages (2013)

3T3-L1 adipocytes express the B-cell-activating factor (BAFF) and three different BAFF receptors (BAFF-Rs). Furthermore, BAFF expression is regulated by inflammatory modulators, such as tumor necrosis factor-α and rosiglitazone. Here we investigated the function of BAFF in 3T3-L1 adipocytes and RAW 264.7 macrophages. We examined adipokine expression in 3T3-L1 adipocytes treated with 10 ng ml(-1) BAFF. We also examined inflammatory molecule expression in RAW 264.7 macrophages treated with 10 or 100 ng ml(-1) BAFF. We examined BAFF expression in the coculture of 3T3-L1 adipocytes and RAW 264.7 macrophages, as well as in white adipose tissue (WAT) of diet-induced obese (DIO) mice. We found that BAFF decreases leptin and adiponectin expression, but increases the expression of proinflammatory adipokines monocyte chemotactic protein-1, interleukin-6 (IL-6), cyclooxygenase-2 (COX-2) and haptoglobin. Coculturing the two cell types resulted in increased BAFF mRNA and protein expression, as well as modulation of BAFF-R mRNA expression in both cell types. These data indicate that BAFF might mediate adipocyte and macrophage interaction. When RAW 264.7 macrophages were treated with BAFF, BAFF-R expression was modulated as in coculture, and nitric oxide synthase and IL-6 expression increased. BAFF expression also increased in WAT of DIO mice. We propose that BAFF can regulate adipokine expression and possibly mediate adipocyte and macrophage interaction.
The Impact of Wireless Application Protocol (WAP) on M-Commerce Security (2002)

Abstract Mobile commerce (m-commerce) is providing commercial services that are accessible using mobile devices, typically a mobile phone. The main advantage of such services is their high availability, independent of physical location and time. Yet the move to create a wireless version of the Internet means a new set of problems. As with the existing fixed Internet, the biggest problem is security. Despite the fact that operators are announcing or rolling out Wireless Applications Protocol (WAP)-based information and transaction services, the platform has gaping security holes. Because security is the most important feature to the success of m-commerce, this paper studies the security concerns on wireless commercial Internet and presents the features and solutions of WAP to the security of electronic transactions. Most importantly, this paper intends to draw corporate executives' attention to the strong impact of WAP on m-commerce security and the associated benefits to their companies.
A review of wind power forecasting & prediction (2016)

Due to the stochastic and intermittent nature of wind power, the accuracy of wind power prediction(WPP) is of great significance to the grid with increasing wind farm penetration. Currently the methods of WPP is various and uneven. Hence forecasting methods are detailedly classified and summarized in this paper, and the basic ideas, advantages and disadvantages of these methods are discussed in detail. The paper presents the analysis of state-of-the-art worldwide research, and the outlook of the main research directions of WPP.
Reduced Volume of Limbic System–Affiliated Basal Ganglia in Mood Disorders: (1999)

Volumes of basal ganglia in postmortem brains of 8 patients with mood disorders and 8 control subjects without neuropsychiatric disorder were determined. Morphometry of serial whole-brain sections under the control of postmortem artifacts revealed reduced volumes of the left nucleus accumbens (-32%, P = 0.01), the right and left external pallidum (-20%, P = 0.04), and the right putamen (-15%, P = 0.04) in the patient group compared with the control group. These results suggest that, in particular, the limbic loop of the basal ganglia involving the nucleus accumbens and the pallidum is affected in mood disorders.
Wireless wires (2007)

In this paper we describe the motivations, the rationale and a solution to build a web of things in which people have the important role to build new connections between real objects using a simple interaction based on pointing visual tags. Some scenarios are described and in particular the conference room scenario is analyzed in depth and a real prototype that implements this scenario is showed.
THE BINDING OF ESTRADIOL IN THE UTERUS: A MECHANISM FOR DEREPRESSION OF RNA SYNTHESIS (1964)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Overcoming the Refractory Expression of Secreted Recombinant Proteins in Mammalian Cells through Modification of the Signal Peptide and Adjacent Amino Acids (2016)

The expression and subsequent purification of mammalian recombinant proteins is of critical importance to many areas of biological science. To maintain the appropriate tertiary structure and post-translational modifications of such proteins, transient mammalian expression systems are often adopted. The successful utilisation of these systems is, however, not always forthcoming and some recombinant proteins prove refractory to expression in mammalian hosts. In this study we focussed on the role of different N-terminal signal peptides and residues immediately downstream, in influencing the level of secreted recombinant protein obtained from suspension HEK293 cells. Using secreted alkaline phosphatase (SEAP) as a model protein, we identified that the +1/+2 downstream residues flanking a heterologous signal peptide significantly affect secreted levels. By incorporating these findings we conducted a comparison of different signal peptide sequences and identified the most productive as secrecon, a computationally-designed sequence. Importantly, in the context of the secrecon signal peptide and SEAP, we also demonstrated a clear preference for specific amino acid residues at the +1 position (e.g. alanine), and a detrimental effect of others (cysteine, proline, tyrosine and glutamine). When proteins that naturally contain these "undesirable" residues at the +1 position were expressed with their native signal peptide, the heterologous secrecon signal peptide, or secrecon with an additional alanine at the +1 or +1 and +2 position, the level of expression differed significantly and in an unpredictable manner. For each protein, however, at least one of the panel of signal peptide/adjacent amino acid combinations enabled successful recombinant expression. In this study, we highlight the important interplay between a signal peptide and its adjacent amino acids in enabling protein expression, and we describe a strategy that could enable recombinant proteins that have so far proved refractory to expression in HEK293 cells, to be produced in sufficient quantities to answer important biological questions.
Process‐based quality management for clinical implementation of adaptive radiotherapy (2014)

Results of the FMEA-based risk assessment demonstrate that intensity-modulated ART introduces different (but not necessarily more) risks than standard IMRT and may be safely implemented with the proper mitigations.
Periodic Travelling Wave Photodetectors with Serial and Parallel Optical Feed Based on InP (2006)

In der Dissertation werden monolithisch integrierte periodische Wanderwellen-Photodetektoren mit paralleler und serieller optischer Speisung für Hochgeschwindigkeits- und Hochstrom-Anwendungen bei 1,55 µm Wellenlänge entwickelt und charakterisiert. Die untersuchten Photodetektoren basieren auf diskreten, miniaturisierten evaneszent-gekoppelten p-i-n Photodioden, die durch eine Koplanarleitung verschaltet sind und somit eine Wanderwellenstruktur ausbilden. Im Gegensatz zu diskreten Photodetektoren lassen sich Wanderwellen-Photodetektoren in der elektrischen Domäne als kapazitiv-belastete Leitungen oder generell als verteilte Strukturen beschreiben. Durch ein geeignetes Design der Koplanarleitung kann die Impedanz des Wanderwellen-Photodetektors an die der Last angepaßt werden. Liegt außerdem eine Phasenanpassung zwischen dem optischen und elektrischen Signal vor, verbleibt als Bandbreite-Begrenzung lediglich die Ladungsträgertransitzeit und das Bragg-Limit. In Bezug auf die optische Speisung werden zwei unterschiedliche Konzepte untersucht: Im Falle der parallelen optischen Speisung wird das optische Eingangssignal in einem verlustarmen monolithisch integrierten Multimoden-Interferenz-Teiler gleichmäßig auf mehrere Photodioden aufgeteilt. Dieser Typ des Wanderwellen-Photodetektors zeichnet sich insbesondere durch seine Fähigkeit aus, auch Signale hoher optischer Leistung optoelektronisch zu wandeln. Der Wanderwellen-Photodetektor mit serieller optischer Speisung besteht aus einem Zuführungswellenleiter, auf dem die Photodioden hintereinander angeordnet sind. Verglichen mit einer Einzel-Photodiode läßt sich mit diesem Konzept eine gesteigerte Responsivität bei Erhaltung der Bandbreite erreichen. Die theoretische Betrachtungen der optischen und elektrischen Eigenschaften des Wanderwellen-Photodetektors führen im Bauelementeentwurf auf ein Design, welches Impedanz- und Phasenanpassung sowie eine ausreichend hohe Bragg-Frequenz gewährleistet. Durch den Einsatz von kurzen, vielmodigen Wellenleitern im optischen Design kann der Quantenwirkungsgrad aller betrachteten Photodetektoren gesteigert werden. Die experimentell gewonnenen Ergebnisse zeigen, daß die hergestellten Wanderwellenphotodetektoren in zwei wichtigen Parametern, der exzellenten elektrischen Impedanzanpassung an 50 Ohm über einen weiten Frequenzbereich und der maximalen elektrischen Ausgangsleistung, den diskreten Photodetektoren überlegen sind. Die Bandbreiten erreichen dabei erstmalig auch im Falle des parallel-gespeisten Wanderwellenphotodetektors Werte um 85 GHz. Insbesondere bei hohen optischen Leistungen und Signalfrequenzen bis 400 GHz zeigt der Wanderwellen-Photodetektor deutlich bessere Frequenzgangseigenschaften als vergleichbare diskrete Detektoren. Abschließende Experimente demonstrieren die Systemtauglichkeit des Wanderwellen-Photodetektors erstmalig für Bitraten > 80 Gbit/s.
<title>Low-cost fiber optic interferometric sensors</title> (1996)

This paper outlines recent progress made by Optiphase Inc. in the development of low cost fiber optic interferometric sensors. The paper's focus is on components under development, specific to interferometric fiber sensors (IFS), which aren't commercially available through normal telecommunications distribution channels.
[Constituents of Lilium candidum L. and their antioxidative activity]. (2007)

The paper deals with the separation and identification of a flavonoid glycoside from the petals of Lilium candidum L. and the antioxidative properties of the ethanolic extract of the flowers and selected compounds isolated from this species. The isolated flavonoid glycoside was identified as isorhamnetin-3-O-rutinoside by acid hydrolysis, TLC comparison with authentic samples, and UV and mass spectra. Isorhamnetin rutinoside was isolated from Lilium candidum L. for the first time. The antioxidative activity of the ethanolic extract of the flowers and some isolated compounds were determined using DPPH assays.
Low Temperature Synthesis of Flowerlike ZnO Nanostructures by Cetyltrimethylammonium Bromide-Assisted Hydrothermal Process (2004)

The flowerlike ZnO nanostructures, which consisted of swordlike ZnO nanorods, have been prepared by a cetyltrimethylammonium bromide (CTAB)-assisted hydrothermal process at low temperature (120 °C). The XRD pattern indicated that the flowerlike ZnO nanostructures were hexagonal. Furthermore, the SAED and HRTEM revealed that the swordlike ZnO nanorods were single crystal in nature and preferentially grew up along [001]. Finally, the mechanism for the CTAB-assisted hydrothermal synthesis of flowerlike ZnO nanostructures has been preliminarily explained by polar crystal growth theory and surfactant action theory.
Modified Feist broth as a serum-free alternative for enhanced production of protective antigen of Erysipelothrix rhusiopathiae (1990)

The production of protective antigen in modified serum-free nutrient broth (H. Feist, K.-D. Flossmann, and W. Erler, Arch. Exp. Veterinaermed. 30:49-57, 1976) and in brain heart infusion broth supplemented with 10% horse serum (BHIS) was evaluated for six strains of Erysipelothrix rhusiopathiae serotypes 1a, 2, 2b, 4, and N. All six strains grew to higher cell densities in modified Feist medium than in BHIS and produced larger amounts of 64,000- to 66,000- and 39,000- to 40,000-molecular-weight antigens involved in immunity to erysipelas. A vaccine produced in Feist medium from E. rhusiopathiae SE-9 (serotype 2) was highly effective in a mouse protection test. We therefore suggest that modified Feist medium is an excellent, if not superior, alternative to BHIS for production of erysipelas vaccine.
Metallic Cohesion in High Vacuum (1963)

By repeatedly breaking and re-joining notched cylindrical specimens and measuring the true stresses involved, the effects on cohesion of temperature, environmental pressure, time apart and time in compression were evaluated. Compressive stresses were kept as high as possible without increasing specimen diameter excessively. Type 1018 Steel and OFHC Copper were studied in the 25 C to 500 C temperature range and in the 10−9 to 10−6 torr pressure range. Results are presented in the form of graphs relating per cent cohesion to the cumulative product of the time apart and the pressure while apart. The maximum cohesion obtained at room temperature was about 19% for the steel and about 12% for the copper. About 30% was obtained at 90 C on copper. Either exposure at low temperature to residual vacuum system gases reduces cohesion more than exposure at high temperature for both steel and copper or work hardening greatly reduces cohesion.
Digital Control for Improved Efficiency and Reduced Harmonic Distortion Over Wide Load Range in Boost PFC Rectifiers (2010)

This paper focuses on efficiency improvements and harmonic distortion reductions in digitally controlled single-phase boost power-factor-correction (PFC) rectifiers operating over wide load range. Based on a discontinuous conduction mode (DCM) detection circuit, a predictive current control law is modified to improve current shaping in both DCM and continuous conduction mode (CCM). Adaptive switching and adaptive frequency control techniques are introduced to reduce switching losses and improve efficiency at light loads. Experimental results are shown for a 300 W boost PFC rectifier.
Sustained activation of blood coagulation in patients with cerebral thrombosis (1995)

Recent progress in the measurements of the hemostatic markers enables us to assess the detailed profiles of hemostatic activation in various diseases. To evaluate the degree of hemostatic system activation in patients with cerebral thrombosis, detailed coagulation studies were performed in 28 patients with acute-phase cerebral thrombosis and in 36 with chronic-phase cerebral thrombosis, together with 6 with chronic-phase cerebral hemorrhage and 37 age-matched healthy volunteers. In both acute-phase and chronic-phase cerebral thrombosis, plasma levels of thrombin-antithrombin III complex, plasmin-alpha 2-plasmin inhibitor complex and D-dimer were significantly higher, and antithrombin III and protein C were significantly lower than those in the normal group. Plasma fibrinogen concentration was significantly higher in chronic-phase cerebral thrombosis than that in chronic-phase cerebral hemorrhage. No significant difference was found in these variables between acute-phase and chronic-phase cerebral thrombosis. In addition, there was no difference in these parameters between chronic phase cerebral hemorrhage and normal subjects. These findings indicate that a sustained activation of coagulation and fibrinolysis is present in cerebral thrombosis, and it might contribute to the pathogenesis of cerebral thrombosis.
Discovering gold in the north: The evidence changes (2015)

Most accounts of North Queensland history say the first discovery of gold was made in 1865, resulting in the Star River rush. Geoffrey Bolton, writing the first scholarly history of the region in 1963, described how in September 1865 the business community of Townsville, eager to attract population, offered a reward of 1,000 pounds for the discovery of payable gold in their hinterland: Results soon followed. Two months later a station overseer named Gibson reported gold on Michael Miles' Star River station about fifty miles west of Townsville. In January 1866 a public meeting at the port voted him 500 pounds reward, and a small rush set in.
Highly Predictive Genetic Markers Distinguish Drug-Type from Fiber-Type Cannabis sativa L (2019)

Genetic markers can be used in seeds and in plants to distinguish drug-type from fiber-type Cannabis Sativa L. varieties even at early stages, including pre-germination when cannabinoids are not accumulated yet. With this aim, this paper reports sequencing results for tetrahydrocannabinolic acid synthase (THCAS) and cannabidiolic acid synthase (CBDAS) genes from 21 C. sativa L. varieties. Taking into account that THCAS- and CBDAS-derived enzymes compete for the same substrate, the novelty of this work relies in the identification of markers based on both THCAS and CBDAS rather than THCAS alone. Notably, in our panel, we achieved an adequate degree of discrimination (AUC 100%) between drug-type and fiber-type cannabis samples. Our sequencing approach allowed identifying multiple genetic markers (single-nucleotide polymorphisms—SNPs—and a deletion/insertion) that effectively discriminate between the two subgroups of cannabis, namely fiber type vs. drug type. We identified four functional SNPs that are likely to induce decreased THCAS activity in the fiber-type cannabis plants. We also report the finding on a deletion in the CBDAS gene sequence that produces a truncated protein, possibly resulting in loss of function of the enzyme in the drug-type varieties. Chemical analyses for the actual concentration of cannabinoids confirmed the identification of drug-type rather than fiber-type genotypes. Genetic markers permit an early identification process for forensic applications while simplifying the procedures related to detection of therapeutic or industrial hemp.
Contacts between Bacillus subtilis catabolite regulatory protein CcpA and amyO target site (1997)

Catabolite control protein A (CcpA) is a global regulatory protein involved in catabolite repression and glucose activation in Gram-positive bacteria. cis -Acting DNA sequences, catabolite response elements ( cre s), involved in this regulatory system contain a 14 base pair (bp) region of dyad symmetry. CcpA, a repressor of the Lac I family, has been shown to bind specifically to cre s. To better understand cre recognition by CcpA, we have focused on the interaction between CcpA and the amyE cre , called amyO, which is located at the transcription start site of the alpha-amylase gene. DNA-protein complexes were probed with dimethylsulfate (DMS) and N -ethylnitrosourea (EtNU) to identify guanines and phosphates that participate in complex formation. Interaction between amyO and CcpA visualized through methylation protection and interference showed that CcpA contacts guanine residues at the outer bounds of amyO with higher affinity than near the dyad axis. From ethylation interference studies, it was found that CcpA contacts three phosphate groups at each end of amyO, and one or two phosphate groups near the dyad axis. Exonuclease III protection revealed that CcpA protects a 26 bp region centered around the dyad axis of amyO. The isolated N-terminal fragment still specifically bound to the sequence resembling the half sites of the amyO sequence. Considering these findings and the helical structure of B-DNA, our results suggest that each of the two monomers of the CcpA molecule contact the major groove in each half of the region of dyad symmetry and that the contacts are on the same face of the DNA helix, which is typical of bacterial repressor-operator interactions. However, the absence of strong contacts near the dyad axis by CcpA is in contrast to the situation with the gal repressor, another member of the Lac I family of repressors.
A Novel Solvothermal Route to Nanocrystalline Sn<sub>4</sub>P<sub>3</sub> with Red Phosphorous as Raw Material (2013)

Nanocrystalline tin phosphide Sn 4 P 3 was synthesized from red phosphorus and tin chloride SnCl 2 2H 2 O by a low temperature (200°C) solvothermal reaction in ethanolamine for only 10 hours. The important parameters of solvothermal processmolar ratio of initial components (P/Sn), temperature and duration were investigated. The phase, composition and morphology of the products were characterized by X-ray diffraction (XRD), energy dispersive spectroscopy (EDS) and transmission electron microscopy (TEM). The ideal solvothermal conditions to synthesize pure and nanocrystallined Sn4P3 were summarized in this work.