gebhart/patrepeval huggingface dataset:
Determination of the binding of hexanal to soy glycinin and .beta.-conglycinin in an aqueous model system using a headspace technique (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of the binding of hexanal to soy glycinin and .beta.-conglycinin in an aqueous model system using a headspace techniqueSean F. O'Keefe, Lester A. Wilson, Adoraccion P. Resurreccion, and Patricia A. MurphyCite this: J. Agric. Food Chem. 1991, 39, 6, 1022–1028Publication Date (Print):June 1, 1991Publication History Published online1 May 2002Published inissue 1 June 1991https://pubs.acs.org/doi/10.1021/jf00006a003https://doi.org/10.1021/jf00006a003research-articleACS PublicationsRequest reuse permissionsArticle Views343Altmetric-Citations81LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evidence suggesting cis action by the TnaC leader peptide in regulating transcription attenuation in the tryptophanase operon of Escherichia coli (1995)

Expression of the tryptophanase (tna) operon in Escherichia coli is regulated by catabolite repression and transcription attenuation. Elevated levels of tryptophan induce transcription antitermination at one or more Rho factor-dependent termination sites in the leader region of the operon. Induction requires translation of a 24-residue coding region, tnaC, located in the 319-nucleotide transcribed leader region preceding tnaA, the structural gene for tryptophanase. In the present paper, we show that two bacterial species that lack tryptophanase activity, Enterobacter aerogenes and Salmonella typhimurium, allow tryptophanase induction and tna operon regulation when they carry a plasmid containing the E. coli tna operon. The role of tnaC in induction was examined by introducing mutations in a 24-nucleotide segment of tnaC of E. coli surrounding and including the crucial Trp codon 12. Some mutations resulted in a noninducible phenotype; these mostly introduced nonconservative amino acid substitutions in TnaC. Other mutations had little or no effect; these generally were in third positions of codons or introduced conservative amino acid replacements. A tryptophan-inserting, UGA-reading glutamine suppressor tRNA was observed to restore partial regulation when Trp codon 12 of tnaC was changed to UGA. Stop codons introduced downstream of Trp codon 12 in all three reading frames established that induction requires translation in the natural tnaC reading frame. Our findings suggest that the TnaC leader peptide acts in cis to prevent Rho-dependent termination.
Wright-Patterson Air Force Base, Area B, Dayton, Montgomery County, OH (1969)

Significance: Area B began as Wright Field, an important center for a variety of early aircraft engineering and support systems research. Specialized research and support structures here were the site of many innovations in aircraft and equipment design. During the military build-up generated by World War II, the extent and scope of the research conducted by Army Air Corps engineers expanded considerably, as did the facilities at Wright Field. After the war, cutting edge aeronautical research continued at the field, now a part of Wright-Patterson Air Force Base, including efforts important to early space flight technology. Its long history of innovation in the field of aeronautical engineering and the intact condition of many of its significant structures make Wright-Patterson Air Force Base, Area B an important monument to the development of modern flight. 
Unprocessed Field note material exists for this structure: N108 
Unprocessed Field note material exists for this structure: N413 
Survey number: HAER OH-79 
Building/structure dates: 1927 Initial Construction
A Context Menu for the Real World: Controlling Physical Appliances Through Head-Worn Infrared Targeting (2013)

Abstract : We introduce a novel method for selecting and controlling smart appliances in physical spaces through a head-worn computing device with near-eye display and wireless communication. We augment a commercial wearable computing device, Google Glass, with a narrow-beam IR emitter for this purpose. This configuration yields a usable beam width of 2 to 4 feet (60 to 120cm) for targeting at room scale. We describe a disambiguation technique if infrared targeting hits multiple targets simultaneously. A target acquisition study with 14 participants shows that selection using head orientation with our device outperforms list selection on a wearable device. We also report qualitative data from using our device to control multiple appliances in a smart home scenario.
Pre-fusion F is absent on the surface of formalin-inactivated respiratory syncytial virus (2016)

The lack of a licensed vaccine for respiratory syncytial virus (RSV) can be partly attributed to regulatory hurdles resulting from vaccine enhanced respiratory disease (ERD) subsequent to natural RSV infection that was observed in clinical trials of formalin-inactivated RSV (FI-RSV) in antigen-naïve infants. To develop an effective vaccine that does not enhance RSV illness, it is important to understand how formalin and heat inactivation affected the antigenicity and immunogenicity of FI-RSV compared to native virus. Informed by atomic structures of RSV fusion (F) glycoprotein in prefusion (pre-F) and postfusion (post-F) conformations, we demonstrate that FI-RSV predominately presents post-F on the virion surface, whereas infectious RSV presents both pre-F and post-F conformations. This significant antigenic distinction has not been previously appreciated. Thus, a stabilized pre-F antigen is more representative of live RSV than F in its post-F conformation, as displayed on the surface of FI-RSV. This finding has major implications for discriminating current pre-F-based immunogens from FI-RSV used in historical vaccine trials.
Phase-Velocity-Modulated Magnetoelastic Waves (1966)

First Page
A new optical method for studying flames (1973)

A spatial-filtering set-up is used in order to visualize mean turbulences in a flame.
Silicon phthalocyanine (pc 4) photodynamic therapy is a safe modality for cutaneous neoplasms: results of a phase 1 clinical trial (2010)

Pc 4-PDT is a safe and tolerable treatment modality that effectively triggers apoptosis in cutaneous neoplasms such as mycosis fungoides.
Isolation and Characterization of Vasohibin-2 as a Homologue of VEGF-Inducible Endothelium-Derived Angiogenesis Inhibitor Vasohibin (2006)

These results suggest that vasohibin-2, in combination with vasohibin-1, forms a novel family of angiogenesis inhibitors.
Collaborative Relay Beamforming Based on Minimum Power for M2M Devices in Multicell Systems (2013)

Recently, machine-to-machine (M2M) communication has been studied in the single cell system. However, in themulticell system multiple M2M type devices at the edge of a cell may suffer from the strong interference that consists of the intercell interference from other cells and the intracell interference from other M2M devices in the local cell. In this paper, we study the relay beamforming strategy to guarantee the quality of service (QoS) requirements of the multiple destination devices in multicell systems. We minimize the transmit power of the base stations (BSs) and relays to save the power of M2M devices, while guaranteeing the receive signal-to-interference-and-noise ratio (SINR) of the destination devices. The main contribution of this paper is that we propose an iterative algorithm to jointly optimize the BS and relay beamforming weights with minimizing the BS and relay power under the receive SINR constraints in the perfect channel state information (CSI). Using the semidefinite relaxation (SDR) technology, the optimization problems for the BS and relay beamforming weights can be effectively solved. In addition, we also discuss the issue of imperfect CSI in practice. Simulation results validate our theoretical analysis and demonstrate that our proposed iterative scheme can achieve near-optimal performance within a few iterations.
Geographical Inequalities: The Spatial Bias of the New Communications Technologies (1989)

Journal Article Geographical Inequalities: The Spatial Bias of the New Communications Technologies Get access Andrew Gillespie, Andrew Gillespie 1Andrew Gillespie and Kevin Robins are Professors in the Centre for Urban and Regional Development Studies at the University of Newcastle upon Tyne Search for other works by this author on: Oxford Academic Google Scholar Kevin Robins Kevin Robins 1Andrew Gillespie and Kevin Robins are Professors in the Centre for Urban and Regional Development Studies at the University of Newcastle upon Tyne Search for other works by this author on: Oxford Academic Google Scholar Journal of Communication, Volume 39, Issue 3, September 1989, Pages 7–18, https://doi.org/10.1111/j.1460-2466.1989.tb01037.x Published: 07 February 2006
Development of Auditory Phase-Locked Activity for Music Sounds (2009)

The auditory cortex undergoes functional and anatomical development that reflects specialization for learned sounds. In humans, auditory maturation is evident in transient auditory-evoked potentials (AEPs) elicited by speech or music. However, neural oscillations at specific frequencies are also known to play an important role in perceptual processing. We hypothesized that, if oscillatory activity in different frequency bands reflects different aspects of sound processing, the development of phase-locking to stimulus attributes at these frequencies may have different trajectories. We examined the development of phase-locking of oscillatory responses to music sounds and to pure tones matched to the fundamental frequency of the music sounds. Phase-locking for theta (4-8 Hz), alpha (8-14 Hz), lower-to-mid beta (14-25 Hz), and upper-beta and gamma (25-70 Hz) bands strengthened with age. Phase-locking in the upper-beta and gamma range matured later than in lower frequencies and was stronger for music sounds than for pure tones, likely reflecting the maturation of neural networks that code spectral complexity. Phase-locking for theta, alpha, and lower-to-mid beta was sensitive to temporal onset (rise time) sound characteristics. The data were also consistent with phase-locked oscillatory effects of acoustic (spectrotemporal) complexity and timbre familiarity. Future studies are called for to evaluate developmental trajectories for oscillatory activity, using stimuli selected to address hypotheses related to familiarity and spectral and temporal encoding suggested by the current findings.
Identification of the major lectin-binding surface proteins of human neutrophils and alveolar macrophages (1988)

Concanavalin A (Con A) and wheat germ agglutinin (WGA) are frequently used as stimuli of neutrophils and macrophages. While the effects of these lectins on cell function are presumably mediated by interaction with cell-surface molecules, the target structures on the cell surface involved are not well defined. We have used the techniques of lactoperoxidase catalyzed cell-surface iodination, lectin affinity chromatography, monoclonal antibody immunoprecipitation, and NaDodSO4- polyacrylamide gel electrophoresis to study the surface proteins of human neutrophils and alveolar macrophages that react with six lectins including Con A and WGA. We found that several major surface-labeled proteins of neutrophils bound Con A. Four of these proteins were identified by immunoprecipitation as members of the LFA-1/HMac- 1/gp150,95 adhesion glycoprotein family. Con A also bound CR1 and a 135- kd surface-labeled protein recognized by CD15 monoclonal antibodies. WGA also bound many of these proteins, but had a much lower avidity for CR1. All three of the major surface-labeled proteins of human alveolar macrophages bound to Con A, including the 183-kd mannose receptor and the 30-kd smoking-associated protein. WGA also bound the 183-kd macrophage protein, but not the 30-kd protein. These results should aid the understanding of studies using these lectins as stimuli.
Silicon Metabolism in Diatoms. V. Germanium Dioxide, a Specific Inhibitor of Diatom Growth (1966)

In enriched sea-water cultures inoculated with a mixture of algae and other organisms, concentrations of GeO2 above 1.5 mg/l specifically suppressed the growth of diatoms. In experiments with 14 pure cultures of diatoms (10 species), 1 mg GeO2/l sufficed to reduce the growth rates significantly; 10 mg GeO2/l was even more inhibitory to growth, and in a few cases killed the cells. Phaeodactylum tricornutum, the most weakly silicified diatom, was the least sensitive to GeO2 inhibition. In experiments with four selected marine species, an appropriate increase in the SiO2 concentration of the medium reversed the inhibitory action of GeO2 on growth. A similar effect of SiO2 was observed in growth experiments with the fresh-water diatom Navicula pelliculosa. (A non-silicified green fiagellate responded quite differently, its growth being unaffected by relatively high concentrations of GeO2.) At these low concentrations, GeO2 presumably had no effect on respiratory metabolism, since, even in concentrations of GeO2 as high as 400 mg/l, oxygen uptake of N. pelliculosa was unimpaired.All of these experimental results are consistent with the hypothesis that GeO2 is a specific inhibitor of silicate utilization.
Estimation of Water and Oil Relative Permeabilities From Pressure Transient Analysis of Water Injection Well Data (1989)

ABSTRACT This paper presents an interpretation methodology to estimate water and oil relative permeabilities from pressure transient analysis of water injection well data. This study has been carried out in three related parts. In the first part, mathematical equations for injection, fall off and variable-rate injection solutions are derived based on the multicomposite and stepwise multicomposite systems. In the second part, the effect of water and oil relative permeabilities was investigated using the mathematical models. The investigation showed that the characteristics of the relative permeabilities are reflected distinctly in the transient part between the early and late time ranges. In the last part, the inverse problem of estimation of water and oil relative permeabilities from pressure transient data was discussed using the proposed interpretation system, which consisted of the multicomposite model and an improved nonlinear regression algorithm. The study showed that the power-law relative permeability curves can be determined uniquely from pressure falloff data. Interpretation of field examples supported the practicality of the developed approach.
Adaptive Elastic Models for Hand-Printed Character Recognition (1991)

Hand-printed digits can be modeled as splines that are governed by about 8 control points. For each known digit, the control points have preferred &quot;home&quot; locations, and deformations of the digit are generated by moving the control points away from their home locations. Images of digits can be produced by placing Gaussian ink generators uniformly along the spline. Real images can be recognized by nding the digit model most likely to have generated the data. For each digit model we use an elastic matching algorithm to minimize an energy function that includes both the deformation energy of the digit model and the log probability that the model would generate the inked pixels in the image. The model with the lowest total energy wins. If a uniform noise process is included in the model of image generation, some of the inked pixels can be rejected as noise as a digit model is tting a poorly segmented image. The digit models learn by modifying the home locations of the control points.
1,2-Benzisothiazole 1,1-dioxide: a convenient synthesis. The question of the possible aromaticity of 1,2-benzothiazepine 1,1-dioxides (1983)

A convenient synthesis of 1,2-benzisothiazole 1,1-dioxide from toluene-o-sulphonamide is reported, and this allows the preparation of a number of 1,2-benzothiazepine 1,1-dioxides bearing hydrogen atoms in the seven-membered ring; 1H n.m.r. spectroscopy suggests that the later is not aromatic.
Structure-based design of gRNA for Cas13 (2020)

Cas13 endonuclease activity depends on the RNA local secondary structure with strong preference for single-stranded (SS) regions. Hence, it becomes indispensable to identify the SS regions for effective Cas13 mediated RNA knockdown. We herein present rational gRNA design by integrating experimental structure-seq data and predicted structural models. Utilizing structure-seq data for XIST transcript, we observed that gRNAs targeting the SS regions significantly induce transcript knockdown and cleavage than those targeting double-stranded (DS) regions. Further, we identified the "central seed region" in the gRNA that upon targeting the SS regions efficiently facilitates Cas13 mediated cleavage. In our following pursuits, we considered the scenario wherein experimental structure-seq data is not available, hence we used SS18-SSX2 fusion transcript indicated in synovial sarcomas and computationally predicted its structure. We observed that gRNAs targeting the SS regions predicted from the structure, efficiently induced necrosis compared to gRNAs that target the DS regions. In conclusion, for the effective RNA knockdown, the Cas13 mediated targeting strategy presented herein emphasizes the designing of gRNAs specifically targeting SS regions by utilizing structural information. Further, this strategy, in turn, can be anticipated to narrow the search space for gRNA design (by exclusively targeting SS regions) especially when lncRNAs are the targets.
Synthesis and secretion of glycosaminoglycans in cultured retinal pigment epithelium. (1987)

The synthesis and secretion of glycosaminoglycans (GAGs) in primary cultures of feline retinal pigment epithelium (RPE) was measured. After 14 days in culture, the cells were incubated for 3 days with media containing 20 microCi/ml 35SO4 and 10 microCi/ml [3H]-glucosamine. The GAGs were precipitated from the media and cell layer with cetylpyridinium chloride and ethanol, separated in 0.1 M Ba acetate by cellulose acetate electrophoresis, visualized by Alcian blue staining and fluorography, and quantitated by scanning densitometry and liquid scintillation counting. The predominant radioactively-labeled GAG secreted into the media by RPE cultures was chondroitin sulfate (CS), which accounted for 63% of the 35SO4, and 54% of the 3H incorporated. Radioactively-labeled heparan sulfate (HS), dermatan sulfate (DS), and hyaluronic acid (HA) were also identified in the media. Heparan sulfate accounted for 24% of the 35SO4 and 22% of the 3H, DS contained 13% of the 35SO4 and 7% of the 3H, and HA accounted for 17% of the 3H incorporated into the media GAGs. In contrast, fibroblast cultures secreted primarily HA, which accounted for 84% of the 3H in the media GAGs. The profile of GAGs retained by the cell layer was different from that of the secreted GAGs. The predominant radioactively-labeled GAG associated with the cell layer was HS. This GAG contained 54% of the 35SO4, and 52% of the 3H incorporated into cell layer GAGs. Dermatan sulfate contained 23% of the 35SO4, and 23% of the 3H, while CS accounted for 23% of the 35SO4, and 18% of the 3H incorporated into cell layer GAGs. The remaining 7% of the incorporated 3H was associated with HA. Total GAG profiles were determined for primary cultures of feline RPE by Alcian blue staining, and compared with those of freshly isolated cell samples. The GAG profiles were similar in cultured and freshly-isolated samples; however, the percentage of HS in the freshly-isolated samples was about twice as high as the percentage of HS in cultured samples, while the proportion of DS in cultured samples was higher than in freshly-isolated samples. This study demonstrates that the profile of radioactively-labeled GAGs secreted by primary cultures of feline RPE is distinct from that retained by the cell layer. In addition, the total GAG profile of cultured RPE is similar, but not identical, to that of freshly-isolated cells.
Low-Power Optical Bistability in Cadmium Sulfide Platelets (1984)

We report the observation of transverse and whole-beam optical bistability in thin uncoated cadmium sulfide platelets at milliwatt power levels when a laser is tuned to the vicinity of a bound exciton resonance. The characteristics of both processes are quite different and are described separately.
A Low-Cost Open-Hardware Wideband Multiple-Input–Multiple-Output (MIMO) Wireless Channel Sounder (2008)

Due to the complexity of multiple-input-multiple- output (MIMO) wireless channels, direct measurement is the main viable option for accurate characterization. Details on a new low-cost wideband channel sounder are presented, which was mainly constructed from conventional instruments and components. This switched architecture system is similar to commercial channel sounders and has modest cost (< US$ 50000). The sounder operates in the 2- to 8-GHz range with up to 100 MHz of instantaneous bandwidth and supports eight transmitters and receivers, which are sufficient to support the development and assessment of current and future MIMO wireless systems. In this "open-hardware" project, the hardware design and software components are openly available to other researchers interested in developing or enhancing the MIMO measurement capability. The actual systems built at the University of Pretoria, Pretoria, South Africa, and Brigham Young University, Provo, UT, are presented, as are some example studies.
Transport mechanics in systems of orientable particles. IV. convective transport (1974)

Calculations are presented of the mean diffusion, mobility, and related phenomenological tensors in a dilute system of identical nonspherical axisymmetric Brownian particles subject to external forces and couples, and immersed in a general homogeneous linear shear flow. Special attention is paid to irrotational flows (especially elongational flows), and to simple shear (Couette) flow. The diffusion coefficient varies with the shear rate, owing to the dependence of the orientational distribution function on the shear. Rheological properties of these systems are also calculated.