gebhart/patrepeval huggingface dataset:
A Study of Ground-Plane-Level and Vehicle-Level Radiation Patterns of GPS Antenna in Telematics Applications (2007)

This paper studies the impact of antenna placement on the radiation pattern of a Global Positioning System (GPS) antenna in telematics applications. The radiation pattern of a GPS antenna is first measured on 1 m ground-plane. Then the radiation pattern of the same antenna is measured at three distinct locations on a sedan vehicle. Results are presented to show the impact of GPS antenna placement on its radiation pattern and to compare the ground-plane and vehicle-level radiation patterns
A simple density functional theory for inhomogeneous liquids (1984)

A simple free energy functional, which incorporates both ‘local’ thermodynamics and short ranged correlations, is formulated and applied to the calculation of the density profile of fluids near hard walls. For hard sphere fluids the calculated profiles are in reasonable agreement with Monte Carlo results. For a Lennard-Jones liquid the profiles exhibit the phenomenon of wetting by gas; the oscillations in the density profiles become much less pronounced and a layer of gas develops near the wall as the bulk density approaches its value at coexistence. Such behaviour was found earlier in Monte Carlo simulations but is not accounted for by existing integral equation theories based on closures of the wall-particle Ornstein-Zernike equation.
Towards next-generation label-free biosensors: recent advances in whispering gallery mode sensors (2017)

Whispering gallery mode biosensors have been widely exploited over the past decade to study molecular interactions by virtue of their high sensitivity and applicability in real-time kinetic analysis without the requirement to label. There have been immense research efforts made for advancing the instrumentation as well as the design of detection assays, with the common goal of progressing towards real-world sensing applications. We therefore review a set of recent developments made in this field and discuss the requirements that whispering gallery mode label-free sensors need to fulfill for making a real world impact outside of the laboratory. These requirements are directly related to the challenges that these sensors face, and the methods proposed to overcome them are discussed. Moving forward, we provide the future prospects and the potential impact of this technology.
Ponds in the twenty-first century (1995)

Because they are economical reactors, properly designed ponds for waste management will grow in importance in the 21st Century. They will also be important for water and nutrient recycling and for animal feed production. Paddle wheel mixed algal growth ponds are not only a cost effective choice for wastewater oxidation but also are most efficient in fixing solar energy and in reclaiming water, nutrients, and energy from organic wastes. As the human population increases the amount of arable land will soon be less than one hectare per person and, at current world crop productivities of much less than 0.1 g/m 2 /d, one hectare of arable land per person will be insufficient to sustain a projected population of more than six billion by the year 2000. Because the amount of land is finite, the apparent solutions are to increase productivity and, ultimately, to attain a constant population. Microalgae in ponds can produce high protein biomass at a rate of 10 to 20 g/m 2 /d, productivities an order of magnitude greater than land crops. Algae can be combined with grains to produce valuable feed, which through poultry, animals, and fish can improve human nutrition. With improved human nutrition, financial security should increase and birth rates should decline; therefore, algaculture in ponds, together with conventional agriculture, can help reach a stable population and improve the quality of human life.
BK Virus Nephropathy in Renal Transplant Patients in London (2008)

The incidence of BKN in this study is comparable with previous studies, with more favorable outcomes. It supports the association of BKN with potent immunosuppression.
Reconfigurable pipelined 2-D convolvers for fast digital signal processing (1999)

In order to make software applications simpler to write and easier to maintain, a software digital signal-processing library that performs essential signal- and image-processing functions is an important part of every digital signal processor (DSP) developer's toolset. In general, such a library provides high-level interface and mechanisms, therefore, developers only need to know how to use algorithms, not the details of how they work. Complex signal transformations then become function calls, e.g., C-callable functions. Considering the two-dimensional (2-D) convolver function as an example of great significance for DSP's, this paper proposes to replace this software function by an emulation on a field-programmable gate array (FPGA) initially configured by software programming. Therefore, the exploration of the 2-D convolver's design space will provide guidelines for the development of a library of DSP-oriented hardware configurations intended to significantly speed up the performance of general DSP processors. Based on the specific convolver, and considering operators supported in the library as hardware accelerators, a series of tradeoffs for efficiently exploiting the bandwidth between the general-purpose DSP and accelerators are proposed. In terms of implementation, this paper explores the performance and architectural tradeoffs involved in the design of an FPGA-based 2-D convolution coprocessor for the TMS320C40 DSP microprocessor available from Texas Instruments Incorporated. However, the proposed concept is not limited to a particular processor.
Active site mapping of affinity-labeled rat oxidosqualene cyclase. (1994)

Rat liver oxidosqualene cyclase (OSC), a 78-kDa membrane-bound enzyme, was purified and labeled with the mechanism-based irreversible inhibitor, [3H]29-methylidene-2,3-oxidosqualene (Abe, I., Bai, M., Xiao, X.-Y., and Prestwich, G. D. (1992) Biochem. Biophys. Res. Commun. 187, 32-38). A 6-kDa CNBr peptide was separated by Tricine sodium dodecyl sulfate-polyacrylamide gel electrophoresis and blotted to a polyvinylidene difluoride membrane. The sequence of the first 30 amino acids of this peptide were determined by Edman degradation and showed unexpectedly high similarity to the fungal OSC from Candida albicans (50% identity with Arg413-Val442) and to the bacterial squalene cyclase from Alicyclobacillus (formerly Bacillus) acidocaldarius (37% identity with Lys356-Leu385). Further, radioanalysis clearly established that the two adjacent Asp residues in the highly conserved region (Asp-Asp-Thr-Ala-Glu-Ala or DDTAEA) were equally labeled by the irreversible inhibitor. This result provides the first information on the structural details of the active site of OSC and shows for the first time the ancient lineage of this vertebrate enzyme to ancestral eukaryotic and prokaryotic cyclases. Interestingly, the covalently modified DDXX(D/E) sequence of rat liver OSC showed surprising similarity to the putative allylic diphosphate binding site sequence of sesquiterpene cyclases and prenyl transferases.
A sub-burst DFT scheme for CW burst detection in mobile satellite communication (2000)

This paper presents a new idea to detect a continuous-wave (CW) burst with unknown frequency using the discrete Fourier transform. Given a CW burst of certain length, an obvious detection scheme would be to compute the DFT power over the whole burst and in the given frequency bins that cover the total frequency uncertainty range. This may result in poor performance when the CW frequency is not exactly in one of the DFT bins. The new scheme divides the CW burst into L sub-bursts and computes the summation of the DFT power in each sub-burst. With very little increase on the DFT computation complexity, the overall detection performance can he greatly improved. The analysis employs a unified approach to derive the expressions of probabilities of false alarm and miss detection for both the conventional and the new schemes over the additive white Gaussian noise (AWGN) channel. Simulations are done for both the AWGN channel and the satellite fading channel.
Application of poly(<i>N</i>‐isopropylacrylamide) with pendent β‐cyclodextrin to separation of a guest substance in an aqueous solution (1995)

Abstract Poly( N ‐isopropylacrylamide) with pendent β‐cyclodextrin (PNI‐PAAm‐CD) was prepared by copolymerization of acryloyl‐β‐CD and NIPAAm. During the temperature‐induced phase separation of an aqueous solution of PNIPAAm‐CD, Toluidine Blue dye in the solution was separated into the precipitate of PNIPAAm‐CD by way of inclusion complex formation.
Collocation and Telecommunications Policy: A Fostering of Competition on the Merits? (1992)

This article discusses the potential development of competition in the various local telephone service market segments.The Federal Communications Commission, in CC Docket 91-141, is considering requiring telephone companies to lease space inside (or alternatively provide interconnection facilities just outside) their local switching offices to accommodate the placement of competitors' telecommunications equipment, an arrangement known as collocation.An FCC policy decision favoring the collocation of competitors' equipment on telephone company premises will provide strong economic incentives for firms to enter the local telecommunications services market.However, whether increasing the number of firms supplying various local telephone services will automatically achieve either a more efficient industry structure or deliver benefits to consumers typically associated with actively competitive markets is not certain.Allowing all industry suppliers to participate in the competitive process, including incumbent telephone companies, will increase the likelihood that policies designed to foster competition will ultimately produce the full range of social benefits anticipated by regulators.Specifically, unless regulatory constraints prohibiting telephone companies from quickly lowering prices and negotiating individual service contracts with high volume customers are relaxed, implementation of a national collocation policy will probably encourage inefficient market entry while preventing market prices from declining to truly competitive levels.
Nascent Lipidated Apolipoprotein B Is Transported to the Golgi as an Incompletely Folded Intermediate as Probed by Its Association with Network of Endoplasmic Reticulum Molecular Chaperones, GRP94, ERp72, BiP, Calreticulin, and Cyclophilin B (2003)

We have previously demonstrated that endoplasmic reticulum (ER)-resident molecular chaperones interact with apolipoprotein B-100 (apoB) during its maturation. The initial stages of apoB folding occur while it is bound to the ER membrane, where it becomes partially lipidated to form a primordial intermediate. We determined whether this intermediate is dependent on the assistance of molecular chaperones for its subsequent folding steps. To that end, microsomes were prepared from HepG2 cells and luminal contents were subjected to KBr density gradient centrifugation. Immunoprecipitation of apoB followed by Western blotting showed that the luminal pool floated at a density of 1.12 g/ml and, like the membrane-bound pool, was associated with GRP94, ERp72, BiP, calreticulin, and cyclophilin B. Except for calreticulin, chaperone/apoB ratio in the lumen was severalfold higher than that in the membrane, suggesting a role for these chaperones both in facilitating the release of the primordial intermediate into the ER lumen and in providing stability. Subcellular fractionation on sucrose gradients showed that apoB in the Golgi was associated with the same array of chaperones as the pool of apoB recovered from heavy microsomes containing the ER, except that chaperone/apoB ratio was lower. KBr density gradient fractionation showed that the major pool of luminal apoB in the Golgi was recovered from 1.02 < d < 1.08 g/ml, whereas apoB in ER was recovered primarily from 1.08 < d < 1.2 g/ml. Both fractions were associated with the same spectrum of chaperones. Together with the finding that GRP94 was found associated with sialylated apoB, we conclude that correct folding of apoB is dependent on the assistance of molecular chaperone, which play multiple roles in its maturation throughout the secretory pathway including distal compartments such as the trans-Golgi network.
The effect of histidine and cysteine on zinc influx into rat and human erythrocytes. (1995)

1. The effect of histidine and cysteine on the initial rate of zinc influx into rat and human erythrocytes in the presence of bovine serum albumin has been investigated. 2. The L-enantiomers of both amino acids promoted zinc influx into rat erythrocytes in a dose-dependent manner. L-Histidine, but not L-cysteine, also promoted zinc uptake into human erythrocytes. D-Histidine did not promote zinc uptake in either rat or human erythrocytes. In rat erythrocytes D-cysteine was significantly less effective than L-cysteine. 3. The stimulation of zinc influx into rat erythrocytes by 20 mM L-histidine was approximately 4.1 times that seen with human erythrocytes. 4. The influx of zinc in the presence of varying concentrations of L-histidine was linearly related to the calculated concentration of the zinc-bis-histidine complex but not to that of the zinc-mono-histidine complex or the free ionic zinc concentration. 5. These results are discussed in relation to the nature of the transport mechanisms involved.
Up-regulation of narX, encoding a putative 'fused nitrate reductase' in anaerobic dormant Mycobacterium bovis BCG (1999)

Mycobacterium tuberculosis and its closely related but non-pathogenic relative M. bovis Bacille Calmette-Guèrin (BCG) have the capability to adapt to anaerobiosis by shifting down from aerobic growth to a state of non-replicating persistence or dormancy. Here, we report the results of a comparative Northern analysis of 23 genes identified in the tubercle bacillus genome project that might play a role in the energy metabolism under anaerobic conditions. The expression of a majority of the genes was found to be down-regulated in the dormant BCG culture. However, the mRNA level for narX, a putative ‘fused nitrate reductase’ not found in other bacteria, was strongly up-regulated in anaerobic dormant bacilli. narX is the first transcriptionally induced gene in anaerobic dormant mycobacteria and might be a useful marker for monitoring the dormancy response in infected animals.
Cobalt–Iron (Oxy)hydroxide Oxygen Evolution Electrocatalysts: The Role of Structure and Composition on Activity, Stability, and Mechanism (2015)

Cobalt oxides and (oxy)hydroxides have been widely studied as electrocatalysts for the oxygen evolution reaction (OER). For related Ni-based materials, the addition of Fe dramatically enhances OER activity. The role of Fe in Co-based materials is not well-documented. We show that the intrinsic OER activity of Co(1-x)Fe(x)(OOH) is ∼100-fold higher for x ≈ 0.6-0.7 than for x = 0 on a per-metal turnover frequency basis. Fe-free CoOOH absorbs Fe from electrolyte impurities if the electrolyte is not rigorously purified. Fe incorporation and increased activity correlate with an anodic shift in the nominally Co(2+/3+) redox wave, indicating strong electronic interactions between the two elements and likely substitutional doping of Fe for Co. In situ electrical measurements show that Co(1-x)Fe(x)(OOH) is conductive under OER conditions (∼0.7-4 mS cm(-1) at ∼300 mV overpotential), but that FeOOH is an insulator with measurable conductivity (2.2 × 10(-2) mS cm(-1)) only at high overpotentials >400 mV. The apparent OER activity of FeOOH is thus limited by low conductivity. Microbalance measurements show that films with x ≥ 0.54 (i.e., Fe-rich) dissolve in 1 M KOH electrolyte under OER conditions. For x < 0.54, the films appear chemically stable, but the OER activity decreases by 16-62% over 2 h, likely due to conversion into denser, oxide-like phases. We thus hypothesize that Fe is the most-active site in the catalyst, while CoOOH primarily provides a conductive, high-surface area, chemically stabilizing host. These results are important as Fe-containing Co- and Ni-(oxy)hydroxides are the fastest OER catalysts known.
An ultrafast quantum random number generator with provably bounded output bias based on photon arrival time measurements (2011)

We report the implementation of a quantum random number generator based on photon arrival times. Due to fast and high resolution timing we are able to generate the highest bitrate of any current generator based on photon arrival times. Bias in the raw data due to the exponential distribution of the arrival times is removed by postprocessing which is directly integrated in the field programmable logic of the timing electronics.
Risk mapping of heart and skeletal muscle inflammation in salmon farming (2012)

Heart and skeletal muscle inflammation (HSMI) is an infectious disease causing losses to the Norwegian salmon farming industry due to increased mortality and high morbidity in infected salmon. The disease is listed as a notifiable disease on list 3 (national list) by the Norwegian Food Safety Authority. HSMI is believed to be a viral disease, but the association to the recently discovered Piscine reovirus (PRV) remains unclear. Undoubtedly, other factors interact to determine whether PRV-infected fish develop disease or not. In this study, logistic regression was used to model the risk of an outbreak of HSMI at the cohort level, by including spatio-temporal risk factors. The data consisted of fish cohorts grown on geo-referenced farms from 2002 to 2010. The risk factors included were: infection pressure, cohort size (maximum number of fish), cohort index (smolt characteristics), cohort lifespan (months in sea) and a geo-index calculated as the position along a local polynomial regression line based on the longitude and latitude of each farm included in the study. The results showed that the risk of developing HSMI increased with increasing cohort lifespan, increasing infection pressure and increasing cohort size, and was mostly low for cohorts grown on farms in Southern-Norway, high for farms in Mid-Norway and variable for farms in Northern-Norway (based on the geo-index). The final model was used to explore three different scenarios with regards to the risk of developing HSMI, and to calculate the probability for each cohort of developing HSMI, independent of their actual disease-status. The model suggested that the probability of developing HSMI was much higher in Mid-Norway than in the rest of the country. Even though PRV seems to be widely distributed in the environment, the finding that infection pressure has a large influence on the probability of developing HSMI, suggests that it might be possible to reduce the number of clinical outbreaks, if measures are taken to reduce infection pressure. However, the prospects of controlling the spread of HSMI and reducing clinical outbreaks might be difficult because of indications of large distance spread of the disease.
[Synthesis and antibacterial activity of 5-amino-6, 8-difluoro-1-(5-fluoro-2-pyridyl)-7-(3-methyl-1-piperazinyl)-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid and its analogues]. (2001)

In vitro antibacterial activities of the compounds (8-15) against Staphylococcus aureus-16, Escherichia coli-26 and Pseudomonas aeruginosa-17 were lower than control of ciprofloxacin.
Implant Surgery Complications: Etiology and Treatment (2008)

Implant surgery complications are frequent occurrences in dental practice and knowledge in the management of these cases is essential. The aim of this review was to highlight the challenges of treatment plan-related, anatomy-related, and procedure-related surgical complications as well as to discuss the etiology, management and treatment options to achieve a satisfactory treatment outcome.
i-AlGaAs/n-GaAs doped-channel heterostructure insulated gate FET (DC-HIGFET) with n/sup +/-GaAs selectively grown by MOCVD (2003)

i-AlGaAs/n-GaAs heterostructure FETs with n/sup +/-GaAs source and drain regions selectively grown by MOCVD (metal-organic chemical vapor deposition) were developed. Diode I-V characteristics and TEM (transmission electron microscope) observations showed that the epitaxial structures are preserved in the present process. A small source resistance (0.35 Omega -mm) and a minimal threshold voltage shift at a short gate-length 0.3- mu m gate showed a high K value of 650 mS/mm. The high current drivability and the small threshold voltage shift at short gate-lengths suggest the potential of the DC-HIGFETs for LSI applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Bridgeless power factor correction circuits with voltage-doubler configuration (2011)

This paper presents a generalized approach to deriving single-phase power factor correction (PFC) circuits with bridgeless and voltage-doubler structures. The approach requires two dc/dc converters connected in a parallel-input series-output manner. Compared to conventional full-bridge diode rectified PFC circuit, which has two diodes along the input current path, the PFC circuits derived by this approach have one diode only, hence reducing the converter losses. Through the proposed approach, some recently reported bridgeless PFC circuits have been identified and new possible combinations can be generated. A design example of dual buck dc/dc converters operating in discontinuous-input-voltage mode (DIVM) is presented to demonstrate the usefulness of the proposed approach.
Effects of absorption on image quality through a particulate medium (1994)

A new approach to studying the effects of absorption by aerosols and molecular particulates of electromagnetic radiation is presented. In contradiction to the conventional concept that absorption gives rise to constant attenuation, it is shown here that the particulate-absorbed irradiance is spatial frequency dependent. An analytically corrected model of the aerosol modulation transfer function and the aerosol mutual coherence function is presented. An important application of this model is in thermal imaging, in which particulate-absorption effects are very significant.
Studies on Quinolone Antibacterials. V. Synthesis and Antibacterial Activity of Chiral 5-Amino-7-(4-substituted-3-amino-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic Acids and Derivatives. (1996)

We previously demonstrated that 5-amino-7-(3-amino-1-pyrrolidinyl) -1-cyclopropyl-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid (7) has strong in vitro antibacterial activity even against quinolone-resistant bacteria. We examined optimization of the 3-aminopyrrolidine moiety of 7 by introduction of C-alkyl (Me, Et, Pr, di-Me, cyclopropyl) and N-alkyl groups (Me, di-Me). C-Alkylation at the 4-position of the 3-aminopyrrolidine moiety enhanced in vitro and in vivo antibacterial activity. (S)-5-Amino-7-(7-amino-5-azaspiro[2.4]hept-5-yl)-1-cyclopropyl-pyr rolidinyl) -1-cyclopropyl-6-fluoro-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic acid (15b) showed strong antibacterial activity (in vitro antibacterial activity including quinolone-resistant bacteria is 4 times more potent than that of ciprofloxacin (CPFX) (1); in vivo antibacterial activity is 1.5 to 20 times more potent than that of CPFX (1)) and reduced quinolone toxicity (free from both phototoxicity at a dosage of 30 mg/kg in guinea pigs (i.v.) and convulsion when coadministered with 4-biphenylacetic acid at a dosage of 20 micrograms in rats (i.c.v.)). Their selectivity between DNA topoisomerase II (derived from eukaryotic cells) and DNA gyrase (derived from bacterial cells) was about 3000-fold.