gebhart/patrepeval huggingface dataset:
Development of a multifacetted undergraduate program in computer and information science (1972)

Computer and Information Science Departments are usually organized, as was the one at The Ohio State University, by combining already existing courses in computer programming and applications from other departments into one department and adding a few extra courses. This paper is a report concerning how this was done at Ohio State and how the Department has developed since. Suggestions are also included for the organization of new departments at other schools. The report has been arranged in four main sections: a description of the development of the department at Ohio State, a unifying philosophy of the field, a description of the Ohio State undergraduate curriculum in Computer and Information Science, and suggestions for new curricula at other schools.
A SYNTHESIS OF <scp>Dl</scp>-PENTA-<i>N</i>,<i>O</i>-ACETYLVALIOLAMINE (1985)

Abstract Valiolamine, (2S)-(1,2,4,5/3)-5-amino-1-C-hydroxymethyl-1,2,3,4-cyclohexanetetrol, an α-glucosidase inhibitor isolated from Streptomyces hygroseopicus subsp. limoneus, has been synthesized as the racemic penta-N,O-acetyl derivative starting from Dl-1,2,3-tri-O-acetyl- (1,3/2,4)-4-bromo-6-methylene-1,2,3-cyclohexanetriol.
Synthesis of Cypridina Luciferin and Related Compounds. VIII. : Improvement in the Synthesis of Cypridina Luciferin (1970)

The previously reported3) synthesis of Cypridina luciferin (I) by condensation of etioluciferin (II) and the α-keto acidfollowed by reduction gave the yield of only 1.3% and hence it cannot be a practical method. Heating of 2-amino-5-phenylpyrazine (III) with pyruvic acid (IV) also gave an imidazopyrazinone derivative (V) but the yield was as low as 7%. As an alternative method, previously reported condensation of aminopyrazines and glyoxals1) was applied to 2-amino-5-(3-indolyl) pyrazine (VII) and methylglyoxal (VI), and its yield was 70%. This method was therefore applied to the synthesis of I. Thus, condensation of II with dl-sec-butylglyoxal (IX) gave I (racemic) in 80% yield.
Bee Botany in East Africa (1957)

(1957). Bee Botany in East Africa. The East African Agricultural Journal: Vol. 23, No. 2, pp. 119-126.
21 days of mammalian omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes compared to olive oil placebo (2015)

Our data indicates N-3 PUFA supplementation improved peripheral neuromuscular function and aspects of fatigue with an unclear effect on central neuromuscular function. Clinical trial registration NCT0201433.
The abundances of the elements. (1972)

For the immediate cosmic environs, there are three traditional sources of element abundance data, including chondritic meteorites, the solar atmosphere, and a certain type of average of stars near the sun. Cosmic ray material, or at least the particles that were accelerated to very high energies, includes contributions from great distances in the Galaxy, and perhaps from outside the Milky Way system itself. Problems in the determination of solar system abundances are discussed together with some factors affecting the profiles of spectral lines, the abundances of some elements in the solar atmosphere, young stars and the interstellar medium, the helium to hydrogen ratio, the helium isotopes, and abundances of light elements in the Galaxy and in neighboring galaxies.
Fully differential operational amplifiers using CMOS compatible ateral bipolar transistors with improved common-mode regulation (1990)

A new bias circuit for a CMOS compatible lateral bipolar transistor differential pair is presented. The circuit compensates for all process and bias dependent variations of the lateral collector current to emitter current ratio α. Experimental results show that its application to a fully differential amplifier improves the precision of the common-mode output voltage regulation by at least an order of magnitude.
<inline-formula><math display="inline" overflow="scroll"><mrow><mn>30</mn><mtext>-</mtext><mi>nm</mi></mrow></math></inline-formula> half-pitch metal patterning using Motif™ critical dimension shrink technique and double patterning (2009)

Double-patterning lithography appears a likely candidate to bridge the gap between water-based immersion lithography and EUV. A double-patterning process is discussed for 30-nm half-pitch interconnect structures, using 1.2 numerical aperture immersion lithography combined with the MotifTM critical dimension (CD) shrink technique. An adjusted optical proximity correction (OPC) calculation is required to model the proximity effects of the Motif shrink technique and subsequent metal hard mask (MHM) etch, on top of the lithography-based proximity effects. The litho-etch-litho-etch approach is selected to pattern a TiN metal hard mask. This mask is then used to etch the low-k dielectric. The various process steps and challenges encountered are discussed, with the feasibility of this approach demonstrated by successfully transferring a 30-nm half-pitch pattern into the MHM.
Unique Topographical Distribution of M Cells Underlies Reentrant Mechanism of Torsade de Pointes in the Long-QT Syndrome (2002)

These data provide direct evidence supporting the functional expression of M cells in intact myocardium and a central role for M cells in the development of reentrant TdP arrhythmias in LQTS.
Multicomponent one-pot annulations forming 3 to 6 bonds (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMulticomponent one-pot annulations forming 3 to 6 bondsGary H. PosnerCite this: Chem. Rev. 1986, 86, 5, 831–844Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://pubs.acs.org/doi/10.1021/cr00075a007https://doi.org/10.1021/cr00075a007research-articleACS PublicationsRequest reuse permissionsArticle Views2109Altmetric-Citations543LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tailor‐Made Ligands for Biocompatible Nanoparticles (2006)

Designer jackets: Polydentate amino-functionalized poly(ethylene oxide)s with various block lengths are synthesized and used for ligand exchange and phase transfer of quantum dots and magnetic nanoparticles (see scheme; TEM images of the particles before and after the exchange are also shown). The ligands enable the transfer of the previously water-insoluble particles into aqueous media.
Imaging Findings in a Fatal Case of Pandemic Swine-Origin Influenza A (H1N1) (2009)

Radiography showed peripheral lung opacities. CT revealed peripheral ground-glass opacities suggesting peribronchial injury. These imaging findings raised suspicion of S-OIV despite negative H1N1 influenza rapid antigen test results from two nasopharyngeal swabs; subsequently, those results were proven to be false-negatives by reverse transcriptase polymerase chain reaction. This case suggests a role for CT in the early recognition of severe S-OIV.
Plant viral suppressors of post‐transcriptional silencing do not suppress transcriptional silencing (2000)

Homology-dependent gene silencing is a regulatory mechanism that limits RNA accumulation from affected loci either by suppression of transcription (transcriptional gene silencing, TGS) or by activation of a sequence-specific RNA degradation process (post-transcriptional gene silencing, PTGS). The P1/HC-Pro sequence of plant potyviruses and the 2b gene of the cucumber mosaic virus have been shown to interfere with PTGS. The ability of these viral suppressors of PTGS to interfere with TGS was tested using the 271 locus which imposes TGS on transgenes under 35S or 19S promoters and PTGS on the endogenous nitrite reductase gene (Nii). Both P1/HC-Pro and 2b reversed PTGS of Nii genes in 271-containing tobacco plants, but failed to reverse TGS of 35S-GUS transgenes in the same plant. P1/HC-Pro expression from a transgene also failed to suppress either the initiation or maintenance of TGS imposed by the NOSpro-silencing locus, H2. These results indicate that PTGS and TGS operate through unlinked pathways or that P1/HC-Pro and 2b interfere at step(s) in PTGS that are downstream of any common components in the two pathways. The data suggest a simple assay to identify post-transcriptionally silenced transgenic lines with the potential to be stably converted to high expressing lines.
The distribution of phospholipase D in developing and mature plants (1969)

1. The distribution of phospholipase D (phosphatidylcholine phosphatido-hydrolase, EC 3.1.4.4) was examined in the tissues of a number of plants and seeds. 2. The highest activities were found in various swollen storage tissues of certain plants: cabbage, central stalk; cauliflower, flower; celery, swollen leaf stalk; Kohl rabi, swollen stem; carrot, root; pea and marrow, seed. 3. Appreciable activity was retained in pea seeds for at least 1 year after drying. After germination and growth in the dark the total activity present in the cotyledons and also in the whole seedling decreased. 4. In the growing pea seedling (7 days old), about 3% of the total activity was in the plumule, 9% in the root and the remainder in the cotyledons. However, the activity in the root on a dry-weight basis was higher than that in the cotyledons. In both the root and the plumule the activity on a wet- or a dry-weight basis was highest in the growing tip. 5. The activity per dry weight in the roots and aerial parts of pea plants declined to low values as growth continued, but roots struck from cuttings of mature plants showed the same high activity as found in roots from young seedlings with cotyledons attached. 6. The total phospholipids present in the cotyledons of pea seeds were depleted on germination and growth. Of the individual phospholipids, phosphatidylcholine and phosphatidylethanolamine showed the same loss in 11 days as the whole phospholipid fraction, whereas phosphatidylinositol was decreased to a greater extent and cardiolipin and phosphatidylserine were not decreased. There was no increase of phosphatidic acid, as might have been expected if the phospholipids had disappeared through phospholipase D hydrolysis. 7. It is concluded that phospholipase D in plant storage tissues and seeds may be related to the rapid growth involved in their formation rather than being necessary for the utilization of their food reserve substances.
Optimal trajectory design under uncertainty (2012)

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2012.
Theoretical study of contact-mode triboelectric nanogenerators as an effective power source (2013)

A theoretical model for contact-mode TENGs was constructed in this paper. Based on the theoretical model, its real-time output characteristics and the relationship between the optimum resistance and TENG parameters were derived. The theory presented here is the first in-depth interpretation of the contact-mode TENG, which can serve as important guidance for rational design of the TENG structure in specific applications.
DNA‐Wrapped Single‐Walled Carbon Nanotube Hybrid Fibers for supercapacitors and Artificial Muscles (2008)

DNA–single-walled carbon nanotube (SWNT) hybrid fibers are fabricated. Partial debundling and alignment of the nanotubes reduces junction resistances leading to high conductivities. The DNA is effective, as a mechanical binder and for debundling the SWNTs, even when immersed in liquid electrolytes. Therefore, the DNA–SWNT Fibers show excellent supercapacitor behavior and superior actuation performance. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2008/c1102_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Electroporation of tissue and cells for drug delivery applications (1994)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1994.
When and Where Relative Permeability Modification Water-Shutoff Treatments Can Be Successfully Applied (2006)

Abstract This paper provides guidance on when and where relative- permeabiliy-modification/disproportionate-permeability- reduction (RPM/DPR) water-shutoff (WSO) treatments can be successfully applied for use in either oil or gas production wells. When properly designed and executed, these treatments can be successfully applied to a limited range of oilfield excessive-water-production problems. When these treatments are applicable, they may be placed using bullhead injection (not requiring mechanical zone isolation)—a very favorable feature. However, there are a substantial number of limitations and possible pitfalls relating to the successful application of RPM/DPR WSO treatments. First-time application by an inexperienced operator should be considered a somewhat high-risk undertaking. In order to successfully treat unfractured production wells (i.e., radial flow through matrix rock into the well) that are fully drawn down, the oil and water zones should not be in pressure communication and the oil- producing zone(s) must be producing at 100% oil cut (dry oil). When treating unfractured and multi-zoned production wells that are not fully drawn down, the well's long-term oil- production rate can be increased if the post-treatment drawdown is increased substantially. Treatments that promote short-term (transient) decreased water/oil ratios can, in principle, be applied to many unfractured production wells (that are not totally watered out) in matrix rock reservoirs. However, these latter treatments must be custom designed and engineered on a well-by-well basis. Furthermore, for most wells, the performance and the economics of such transient WSO treatments are generally marginal. An attractive application of RPM/DPR WSO treatments is the use of robust pore-filling gels in the matrix reservoir rock that is adjacent to a fracture(s) when oil and water is being co-produced into the treated fracture.
Aliovalent doping of CeO<sub>2</sub>: DFT study of oxidation state and vacancy effects (2014)

Doping of ceria allows one to tune the mechanical and chemical properties of ceria at will, though the induced vacancies often contribute to the leading term of these modifications.
Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis (2010)

A simplified diagnostic panel of CA19-9, ApoC-I and ApoA-II improves the diagnostic ability of CA19-9 alone and may have clinical utility.
Mapping and Identification of the Major Cell Wall-Associated Components of <i>Mycobacterium leprae</i> (1998)

Mycobacterium leprae, an obligate intracellular pathogen, can be derived only from host tissue and thus affords the opportunity to study in vivo-expressed products responsible for the particular pathogenesis of leprosy. Despite considerable progress in the characterization of the proteins and secondary gene products of M. leprae, there is little information on the nature of the proteins associated with the cell envelope. M. leprae has been fractionated into its major subcellular components, cell wall, cytoplasmic membrane, and soluble cytosol. A number of biochemical markers, including diaminopimelic acid content, monosaccharide composition, mycolic acid, and glycolipid distribution, were applied to their characterization, and two-dimensional gel electrophoresis was used to map the component proteins. A total of 391 major proteins spots were resolved, and 8 proteins were identified based on their reactivity to a panel of monoclonal antibodies and/or relative pI size. Microsequencing of six protein spots present in the cell wall fraction allowed identification of new proteins, including the protein elongation factor EF-Tu and a homolog for the Mycobacterium tuberculosis MtrA response regulator. These results, together with previous studies, contribute to the progressive knowledge of the composition of the in vivo-expressed proteins of M. leprae.
Assessment and Standardization of Autonomous Vehicles (2018)

Autonomous vehicle technology presents a huge challenge to standardization and legal bodies. This is a new, rapidly emerging domain, which has created a complete industry within a mere decade. The objective assessment and quantification of self-driving algorithms and system for safety is now in the focus of numerous Standard Development Organizations, but as of today, only limited aspects of the safety domain are covered. This paper overviews the most recent trends and current international efforts to support the autonomous vehicle developers and manufacturers with an assessment and standard framework. The focus is especially put on the validation of higher level of autonomy self-driving capabilities.
Collapsible user interfaces for information retrieval agents (1998)

This paper presents an architecture for information retrieval agents in which each agent declaratively describes its domain, input, output, and user interface. A mediating piece of software can then assemble software agents for a given information retrieval task, and produce a single, unified user interface for that task from the individual agents' descriptions.
The Effect of Certain Components of Ionized Air on the Growth and Movement of Microcoleus vaginatus (1961)

Richard F. Smith, Wallace H. Fuller, The Effect of Certain Components of Ionized Air on the Growth and Movement of Microcoleus vaginatus, Journal of the Arizona Academy of Science, Vol. 2, No. 1 (Aug., 1961), pp. 20-23
Providing tablets as collaborative-task workspace for human-robot interaction (2013)

In a recent conference on assistive technology in special education and rehabilitation, over 54 percentage of the sessions were directly or indirectly involved with tablets. Following this trend, many traditional assistive technologies are now transitioning from standalone devices into apps on mobile devices. As such, this paper follows this trend by discussing transforming a tablet into an HRI research platform where our robotic system engages the user in social interaction by learning how to operate a given app (task) using guidance from the user. The objective is to engage the robot within the context of the user's task by understanding the task's underlying rules and structures. An overview of the HRI toolkit is presented and a knowledge-based approach in modeling a task is discussed where previously learned cases are reused to solve a new problem.
D-Glucosamine and L-citrulline, precursors in mitomycin biosynthesis by Streptomyces verticillatus (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTD-Glucosamine and L-citrulline, precursors in mitomycin biosynthesis by Streptomyces verticillatusUlfert Hornemann, James P. Kehrer, Carmen S. Nunez, and Richard L. RanieriCite this: J. Am. Chem. Soc. 1974, 96, 1, 320–322Publication Date (Print):January 1, 1974Publication History Published online1 May 2002Published inissue 1 January 1974https://pubs.acs.org/doi/10.1021/ja00808a087https://doi.org/10.1021/ja00808a087research-articleACS PublicationsRequest reuse permissionsArticle Views194Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Prokaryotic calmodulins: recent developments and evolutionary implications. (2001)

Ca2+ is a common intracellular second-messenger molecule in eukaryotic cells and regulates a myriad of cellular processes. Many effects of Ca2+ are mediated by calcium-binding regulatory proteins of the calmodulin superfamily. We propose the idea that calcium-binding proteins originated in high G+C Gram-positive bacteria and were later acquired by eukaryotes.
Adamantyl‐endcapped polyynes (2011)

Polyynes spanning from a diyne to a dodecayne with adamantyl endgroups have been synthesized using the Fritsch–Buttenberg–Wiechell rearrangement as a key step to construct the acetylenic framework. Molecular properties as a function of polyyne length have been analyzed by UV–Vis spectroscopy, cyclic voltammetry, differential scanning calorimetry, and X‐ray crystallography. Copyright © 2011 John Wiley & Sons, Ltd.
Tm-pass polariser using metal-clad waveguide with high index buffer layer (1988)

The four layer planar metal-clad optical waveguide is shown to provide favourable transmission for TM waves in comparison with TE waves when a thin high-index buffer layer is inserted between the guiding film and the metallic layer. A perturbative expression for the loss of the two polarisations is given.
Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect <i>in vivo</i> (1995)

Albumin is a multifunctional transport protein that binds a wide variety of endogenous substances and drugs. Insulins with affinity for albumin were engineered by acylation of the epsilon-amino group of LysB29 with saturated fatty acids containing 10-16 carbon atoms. The association constants for binding of the fatty acid acylated insulins to human albumin are in the order of 10(4)-10(5) M-1. The binding apparently involves both non-polar and ionic interactions with the protein. The acylated insulins bind at the long-chain fatty acid binding sites, but the binding affinity is lower than that of the free fatty acids and depends to a relatively small degree on the number of carbon atoms in the fatty acid chain. Differences in affinity of the acylated insulins for albumin are reflected in the relative timing of the blood-glucose-lowering effect after subcutaneous injection into rabbits. The acylated insulins provide a breakthrough in the search for soluble, prolonged-action insulin preparations for basal delivery of the hormone to the diabetic patient. We conclude that the biochemical concept of albumin binding can be applied to protract the effect of insulin, and suggest that derivatization with albumin-binding ligands could be generally applicable to prolong the action profile of peptide drugs.