gebhart/patrepeval huggingface dataset:
Results of the clinical examination of an ointment with marigold (Calendula officinalis) extract in the treatment of venous leg ulcers. (2005)

The aim of this study was to determine the therapeutic efficacy of marigold (Calendula officinalis) extract on the epithelialization of lower leg venous ulcers. The experiment was carried out in 34 patients with venous leg ulcers. The patients were divided into two groups. In the first (experimental) group, patients were treated with an ointment containing marigold extract, which was prepared in an apparatus devised by Soxleth and was incorporated into a neutral base. Twenty-one patients with 33 venous ulcers were treated. Therapy was applied twice a day for 3 weeks. The second group was a control group that consisted of 13 patients with 22 venous ulcers. In the control group, saline solution dressings were applied to ulcers for 3 weeks. In the experimental group the total surface of all the ulcers at the beginning of the therapy was 67,544 mm2. After the third week the total surface of all the ulcers was 39,373 mm2 (a decrease of 41.71%). In seven patients, complete epithelialization was achieved. In the control group the total surface of all the ulcers at the beginning of the therapy was 69,722 mm2. After the third week the total surface of all the ulcers was 58,743 mm2 (a decrease of 14.52%). In four patients, complete epithelialization was achieved. There was a statistically significant acceleration of wound healing in the experimental group (p < 0.05). The results obtained are preliminary, but they suggest the positive effects of the ointment with marigold extract on venous ulcer epithelialization.
Increasing role of the cancer chemotherapeutic doxorubicin in cellular metabolism (2016)

Further understanding of doxorubicin's influence on cell biological events could lead to an improvement in the drug's efficacy and reduce toxicity.
Using Virtualization to Improve Software Rejuvenation (2007)

In this paper, we present an approach for software rejuvenation based on automated self-healing techniques that can be easily applied to off-the-shelf Application Servers and Internet sites. Software aging and transient failures are detected through continuous monitoring of system data and performability metrics of the application server. If some anomalous behavior is identified the system triggers an automatic rejuvenation action. This self-healing scheme is meant to be the less disruptive as possible for the running service and to get a zero downtime for most of the cases. In our scheme, we exploit the usage of virtualization to optimize the self-recovery actions. The techniques described in this paper have been tested with a set of open-source Linux tools and the XEN virtualization middleware. We conducted an experimental study with two applications benchmarks (Tomcat/Axis and TPC-W). Our results demonstrate that virtualization can be extremely helpful for software rejuvenation and fail-over in the occurrence of transient application failures and software aging.
Implementation of an Incremental MDL-Based Two Part Compression Algorithm for Model Inference (2009)

We describe the implementation and performance of a compression-based model inference engine, MDLcompress. The MDL-based compression produces a two part code of the training data, with the model portion of the code being used to compress and classify test data. We present pseudo-code of the algorithms for model generation and explore the conflicting requirements between minimizing grammar size and minimizing descriptive cost. We show results of a MDL model-based classification system for network traffic anomaly detection.
Transition Structures for 3-D Integration of Substrate Integrated Waveguide Interconnects (2007)

Two transition structures, via and aperture transitions, used for 3-D integration of substrate integrated waveguide interconnects are investigated in this letter. Equivalent circuits for both structures are presented and evaluated through parametric studies and error analysis in comparison with fullwave simulations. The models are also validated by measurements of two test-boards containing the via and aperture transitions.
Growth of SiC by ?Hot-Wall? CVD and HTCVD (1997)

A reactor concept for the growth of high-quality epitaxial SiC films has been investigated. The reactor concept is based on a hot-wall type susceptor which, due to the unique design, is very power efficient. Four different susceptors are discussed in terms of quality and uniformity of the grown material. The films are grown using the silane–propane–hydrogen system on off-axis (0001) 6H- and 4H-SiC substrates. Layers with doping levels in the low 1014 cm—3 showing strong free exciton emission in the photoluminescence spectra may readily be grown reproducibly in this system. The quality of the grown layers is also confirmed by the room temperature minority carrier lifetimes in the microsecond range and the optically detected cyclotron resonance data which give mobilities in excess of 100000 cm2/Vs at 6 K. Finally, a brief description will be given of the HTCVD technique which shows promising results in terms of high quality material grown at high growth rates.
Systematic, Single Limited Magnitude Error Correcting Codes for Flash Memories (2011)

A relatively new model of error correction is the limited magnitude error model. That is, it is assumed that the absolute difference between the sent and received symbols is bounded above by a certain value <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$l$</tex></formula> . In this paper, we propose systematic codes for asymmetric limited magnitude channels that are able to correct a single error. We also show how this construction can be slightly modified to design codes that can correct a single symmetric error of limited magnitude. The designed codes achieve higher code rates than single error correcting codes previously given in the literature.
An Inverse Problem of Optimal Regulator (1972)

An inverse problem of the optimal regulator is considered for a class of multi-input systems described in a new canonical form. Due to a compact structure of the systems, the analyses are conveniently performed to get relevant characteristics of optimal control systems. Necessary and sufficient conditions for optimized performance indices are given. Assumed that nonlinearities of the system exist only in the part of the directly controlled state variables, a further investigation is directed to the nonnegative property of optimized loss function. In the context, two major topics are considered. One is concerned with a question, “What performance indices can be optimized by identically zero feedback control law?” The other is “What performance indices can be optimized in a linearly synthesized feedback control system?” As an arbitrary system can be transformed into the canonical form, the assumption about the system structure does not restrict the applicability of the results obtained in this paper to general problems.
Drosophila proliferating cell nuclear antigen (cyclin) gene: structure, expression during development, and specific binding of homeodomain proteins to its 5'-flanking region. (1990)

The genomic and cDNA clones for a Drosophila melanogaster proliferating cell nuclear antigen (PCNA) (cyclin) were isolated and sequenced. The coding sequence for a 260-amino-acid residue polypeptide was interrupted by a single short intron of 60 base pairs (bp), and about 70% of the deduced amino acid sequence of the Drosophila PCNA was identical to the rat and human PCNA polypeptides, with conserved unique repeats of leucine in the C-terminal region. Genomic Southern blot hybridization analysis indicates the presence of a single gene for PCNA per genome. The PCNA mRNA was detected at a high level in adult ovaries, unfertilized eggs, and early embryos and at low levels in the other developmental stages. The major transcription initiation site (cap site) was localized at 89 bp upstream from the ATG codon. Neither a TATA box nor a CAAT box was found within the 600-bp region upstream of the cap site. Clusters of 10 bp of sequence similar to the binding sites for Drosophila proteins containing homeodomains were found in the region from -127 to -413. DNase I footprint analysis revealed that the Drosophila homeodomain proteins coded by even-skipped and zerknüllt genes can specifically bind to these sites. These results suggest that the expression of the PCNA gene is under the control of genes coding for homeodomain proteins.
Recent development and applications of electron, ion and plasma sources based on vacuum arc and low pressure glow (2004)

Summary form only given. The paper presents status of experimental research and ongoing development for a number of charged particle sources and plasma guns developed in joint research team from Tomsk, included Plasma sources laboratory (HCEI), Plasma emission laboratory (TUSUR) and small business company "ELION LTD". This work was made in close collaborations with several research groups both Russian and worldwide, such as ITEP, Moscow, IAP Nizny Novgorod, LBNL, Berkeley and BNL, Brookhaven, both USA, GSI-Darmstadt, Germany, and some others. Plasmas for all kind if the sources are generated in "cold wall" electrode (filament-less) discharge systems: cathodic spot vacuum arc, low pressure arc, crossed ExH discharges and hollow cathode glow. The following plasma equipment with its application areas are reviewed: upgraded vacuum arc ion sources to produce especially multiply charged high current ion beam for heavy ion accelerators and surface treatment technology; gaseous ion sources and plasma guns based on hollow cathode glow with external electron beam injection to extend working pressure range for surface cleaning and activation before and during thin film deposition; plasma cathode dc electron guns based on reflected ExB discharge for e-beam welding and e-beam metal powder cladding; plasma cathode dc electron guns based on hollow cathode glow to produce electron beams of cylindrical and ribbon shapes at fore-pump pressure range for plasma chemistry.
Choline kinase: a novel target for antitumor drugs. (2001)

Malignant cells are characterized by the accumulation of genetic alterations, which result in the disregulation of signal transduction pathways that control proliferation, differentiation and apoptosis. The identification of the molecular components involved in these aberrant processes is necessary for the development of chemotherapeutic interventions to restore or selectively destroy the transformed cells. Discovery of new chemotherapeutic agents is probably one of the most reliable ways to improve our success against cancer, and intelligent drug design is a key factor to achieve this goal. Thus, the identification of novel targets for anticancer drug discovery is needed. This review provides evidence to support choline kinase as one such target.
Freeform Lens Design for Illumination with Different Luminance Intensities (2015)

Mapping of equi-luminous fluxes from a point source through a freeform lens for illumination with different luminance intensities is studied. The freeform surface is associated with the mapping and the grids to design on a target plane. Relocation of the target grids designed for uniform illumination is proposed by comparing the grids with reference and desired ones for interpolation to achieve the desired illumination distribution. Target-grids relocation for rectangular illumination with vertical, horizontal, tilt, circular, ring and rectangular cut-off for two different luminance intensities is demonstrated. The target grids after relocation are smooth in distribution, and the lens with a smooth freeform surface is achieved. The adequacy of the proposed methodology is proved by simulation.
Thallium-Based High-Temperature Superconductors (2020)

Historical Perspective on the Discovery of Tl-Based HTSC Oxides, Allen M. Hermann Solid-State Chemistry of Thallium Oxides, J. Gopalakrishnan Crystallographic Aspects, Yuichi Shimakawa Extended Defects and Redox Mechanisms in Thallium Cuprates, Bernard Raveau, Maryvonne Hervieu, and Claude Michel Structures and Superstructures of Tl-Ba-Ca-Cu-O Superconductors, A. W. Hewat and E. A. Hewat Synthesis of Tl-Based High-Tc Superconductive Oxides, Eli Ruckenstein and Nae-Lih Wu Chemical Characterization of Thallium Cuprate Superconductors, Mariappan Paranthaman, Arumugam Manthiram, and John B. Goodenough Single-Crystal Growth and Characterization of Thallium Cuprate Superconductors: A Review, Mariappan Paranthaman, H. M. Duan, and Allen M. Hermann Tl-Based HTSC Films for Microelectronics Applications, David S. Ginley Spray Pyrolysis, L. Pierre de Rochemont and Michael R. Squillante Liquid-Gas Solidification Method for Synthesis of Tl-Based HTSC Oxides, Ho Sou Chen Electrodeposited Tl-Ba-Ca-Cu-O Superconductors, R. N. Bhattacharya and R. D. Blaugher Tl-Ca-Ba-Cu-O Electronics, J. S. Martens TBCCO Ag-Sheathed Tapes, Koji Tada, Hiromi Takei, and Yasuko Torii Effects of Inherent (Auto) Doping and Oxygen Nonstoichiometry and Their Relationship to the Band Structure of Tl-Based Superconductors, R. S. Liu and Peter P. Edwards Structureal Origin of Holes in Thallium Cuprate-Based High-Tc Superconductors, M. A. Subramanian and Ashok K. Gangull Dependence of Tc on the Hole Concentration in Superconducting Thallium Cuprates with Single Tl-O Layers, C. N. R. Rao Site-Selective Substitution in Tl Cuprates, R. M. Iyer and G. M. Phatak Thermal Stability of Tl-Ba-Ca-Cu-O High-Tc Superconductors, Ken H. Sandhage and Patrick K. Gallagher Magnetic Properties of Thallium-Based Superconductors, Timir Datta Effects of Pressure on Thallium-Based Superconductors, Norman E. Moulton and Earl F. Skelton Specific Heat of Thallium Oxide Superconductors, Robert A. Fisher, Norman E. Phillips, and Joel E. Gordon Infrared Studies of Thallium Cuprate Superconductors, Karl F. Renk X-Ray Photoemission of Tl-Based Cuprate Superconductors, Yasuo Fukuda, Teruo Suzuki, and Masayasu Nagoshi Nuclear Resonance Studies of Tl-Based High-Tc Superconductors, Hans B. Brom Normal-State Transport Properties of TBCCO, D. G. Naugle and A. B. Kaiser Tunneling Spectroscopy of Thallium-Based High-Temperature Superconductors, John Moreland Band Structures of Tl-Ba-Ca-Cu-O Materials, Roland E. Allen and Brent A. Richert Thallium Cuprate Research by the U. S. Government, M. S. Davis and S. A. Wolf Thallium Safety, Gary E. Myers Prospects and Potential for Thallium Cuprate Superconductors, J. V. Yakhmi and Allen M. Hermann
Dielectric properties and structural phase transitions in TMMnC (N(CH<sub>3</sub>)<sub>4</sub>MnCl<sub>3</sub>) type crystals (1992)

Abstract Dielectric properties have been studied for single crystals of various TMMnC (N(CH3)4MnCl3)-type compounds; TMMnC, TMMnB, TMNiC, TMNiB, TMCdC, TMCdB, and TMCuC, Dielectric constants show stepwise anomalies at the structural phase transitions of these compounds. In TMCdB, ferroelectricity is found below the Curie temperature of about 156 K (on cooling). For other compounds, no ferroelectricity nor pyroelectricity has been detected in the low temperature phases.
Effect of channel estimation error in OFDM-based WLAN (2002)

We examine the performance degradation due to the channel estimation error in orthogonal frequency division multiplexing (OFDM)-based wireless LAN (WLAN). The average effective SNR and average bit error probabilities (BEPs) are derived in a Rayleigh fading channel.
Inhibition of Capillary Morphogenesis and Associated Apoptosis by Dominant Negative Mutant Transforming Growth Factor-β Receptors (1995)

Transforming growth factor-beta 1 (TGF-beta 1) induces angiogenesis in vivo and capillary morphogenesis in vitro. Two receptor serine/threonine kinases (types I and II) have been identified as signal transducing TGF-beta receptors. We explored the possibility of inhibiting TGF-beta-mediated events in glomerular capillary endothelial cells using a TGF-beta type II receptor (T beta R-II) transdominant negative mutant. A mutant TGF-beta type II receptor (T beta R-IIM), lacking the cytoplasmic serine/threonine kinase domain, was produced by polymerase chain reaction using rat T beta R-II cDNA as template. Since T beta R-II and TGF-beta type I receptor (T beta R-I) heterodimerize for signal transduction, the mutant receptor competes for binding to wild-type T beta R-I, hence acting in a dominant negative fashion. Glomerular capillary endothelial cells were stably transfected with T beta R-IIM, and four independent clones were expanded. That the T beta R-IIM mRNA was expressed was shown by reverse transcriptase-polymerase chain reaction, RNase protection assay, and Northern analysis. Presence of cell surface T beta R-IIM protein was shown by affinity cross-linking with 125I-TGF-beta 1. In wild-type endothelial cells, TGF-beta 1 (2 ng/ml) significantly inhibited [3H]thymidine incorporation to 63 +/- 10% of control (n = 4). In transfected endothelial cells carrying T beta R-IIM, TGF-beta 1 stimulated [3H]thymidine incorporation to 131 +/- 9% of control (n = 4, p < 0.005). Also, in wild-type endothelial cells, endogenous and exogenous TGF-beta 1 induced apoptosis and associated capillary formation. Both apoptosis and capillary formation were uniformly and entirely absent in transfected endothelial cells carrying T beta R-IIM. This represents the first demonstration that capillary morphogenesis in vitro is associated with apoptosis, and that interference with T beta R-II signaling inhibits this process in glomerular capillary endothelial cells.
Challenge-response generation using RO-PUF with reduced hardware (2016)

Cryptography looks forward to generate secrete key from integrated circuit. A silicon based device having uncontrollable feature in term of measurable output can turned into physically unclonable function (PUF). Multiplexer based PUF works on unpredictable delay difference between two parallel paths, while Ring oscillator based PUF works on frequency deviation generated due to random variation of CMOS fabrication process. Hardware based intrinsic features must include to generate a random response which fuzzified to generate a reliable secret key. Our design incorporates PUF based on circuit variation instead of process variation, PISO shift register reduce the hardware compared to existing RO-OUF. A 4-bit challenge generates 16-bit random response with measured reliability in term of intra hamming distance approx to mid value.
Powertrain, steering and control components for the NMBU Agricultural Mobile Robotic Platform (2014)

The first part of this thesis addresses the design of the NMBU Mobile Agricultural Robot's drivetrain and steering assembly, while the second part discusses aspects related to controlling these systems.\n\nPart I:\nFirst, power requirements are calculated based on the expected \\textit{worst case} scenario. Second, the principle design of the systems is determined and parts are selected. For the drivetrain, a hub reduction system is used. The system comprises of four separate \\textit{wheel modules}, each with one brushless DC motor installed over the module's wheel. Power is transferred to an in-wheel planetary gearbox via a timing belt. For the steering assembly, brushless integrated servomotors with planetary gearboxes are used. The power distribution system is also discussed, and two designs are proposed, one for future and one for immediate implementation.\n\nAll parts are selected based on availability, quality and cost. As a result, the components for the drivetrain are not perfectly matched. However, they allow for testing of the basic principle. Preliminary tests of the powertrain and steering assembly show promising results.\n\nPart II:\nDifferent components related to communication and control of the robot are presented, and the principle design of the motor control system is determined with interoperability between current and future systems in mind. \\textit{ROS} (Robotic Operating System) is selected to be used as the robotic framework, and the main computer and the various motor controllers are to communicate using the \\textit{CANopen} protocol. The process of configuring the propulsion motor controllers to match the propulsion motors is described, as is the process of setting up the servomotors. Problems were faced using the propulsion motors built in \\textit{Hall sensors} for feedback in \\textit{closed loop speed mode}, as the sensor assembly’s resolution proved to be too coarse. Alternative feedback sensors are then proposed.
Analysis of plasma viral RNA levels during acute dengue virus infection using quantitative competitor reverse transcription‐polymerase chain reaction (2001)

There is increasing recognition of the potential importance of viral burden in the pathogenesis of dengue hemorrhagic fever (DHF). There is little data available, however, describing the kinetics of viral replication in humans with natural dengue virus (DV) infection. Standard procedures for measuring titers of infectious virus in clinical specimens are either laborious or insensitive. We developed a method for measurement of DV RNA in plasma samples based on reverse transcription-polymerase chain reaction (RT-PCR) using a mutant RNA target as a competitor. This technique was reproducible and accurate for samples containing any of the four DV serotypes, and could be applied to samples containing as few as 250 copies of RNA per reaction. We examined plasma viral RNA levels in 80 children with acute DV infection; sequential plasma samples were tested in 34 of these children. Plasma viral RNA levels ranged as high as 109 RNA copies/ml, and correlated with titers of infectious virus measured in mosquitoes (r = 0.69). Plasma viral RNA levels fell rapidly during the last several days of the febrile period. We did not find a significant difference in maximal plasma viral RNA levels between children with DHF and children with dengue fever, but peak viral RNA levels were identified in only 16 subjects. We conclude that this quantitative RT-PCR method will be valuable for further studies of natural DV infections. J. Med. Virol. 63:29–34, 2001. © 2001 Wiley-Liss, Inc.
40 km Fiber Transmission of Time Domain Multiplexed MIMO RF Signals for RoF-DAS over WDM-PON (2012)

We report the 40 km fiber transmission of MIMO RF signals with time domain multiplexing for RoF-DAS over WDM-PON architecture. No transmission degradation is observed over 12-dB optical received power range.
Occurrence of the Thraustochytrid, <i>Corallochytrium limacisporum </i>gen. et sp. nov. in the Coral Reef Lagoons of the Lakshadweep Islands in the Arabian Sea (1987)

Article Occurrence of the Thraustochytrid, Corallochytrium limacisporum gen. et sp. nov. in the Coral Reef Lagoons of the Lakshadweep Islands in the Arabian Sea was published on January 1, 1987 in the journal Botanica Marina (volume 30, issue 1).
Microsphere-based interferometric optical probe (2018)

Fluorescent optical probes have rapidly transformed our understanding of complex biological systems by providing specific information on biological targets in the natural living state. However, their utility is often limited by insufficient brightness, photostability, and multiplexing capacity. Here, we report a conceptually new optical probe, termed 'reflectophore', which is based on the spectral interference from a dielectric microsphere. Reflectophores are orders-of-magnitudes brighter than conventional fluorophores and are free from photobleaching, enabling practically unlimited readout at high fidelity. They also offer high-degree multiplexing, encoded in their optical size, which can be readily decoded through interferometric detection with nanoscale accuracy, even in turbid biological media. Furthermore, we showcase their biological applications in cellular barcoding and microenvironmental sensing of a target protein and local electric field.