gebhart/patrepeval huggingface dataset:
Enhanced EAP-Based Pre-Authentication for Fast and Secure Inter-ASN Handovers in Mobile WiMAX Networks (2012)

Mobile WiMAX is yet to meet the expectation from mobile users to provide secured and seamless services. Long delay in the time-consuming authentication procedure is a well-known bottleneck of the IEEE 802.16e handover scheme, causing service disruption when a mobile user moves between base stations. A pre-authentication-based handover scheme for mobile WiMAX networks aims to achieve fast and secure inter-ASN handovers. However, it is shown to be vulnerable to Denial of Service (DoS) and replay attacks. In this paper, we propose an Enhanced EAP-based pre-authentication (EEP) scheme to overcome the vulnerability of the above-mentioned scheme with much less requirements on the computation and communication resources.
Purification and release from quiescence of umbilical cord blood early progenitors reveal their potential to engraft adults. (1994)

Steel factor (SF) increases the frequency of colony formation by CD34+ CD38- cycling cells, but it does not reverse the effect of an autocrine production of transforming growth factor (TGF)-beta 1 by early progenitors of the stem cell compartment. We have used optimal culture conditions supplemented with SF and anti-TGF-beta serum to estimate the proliferative capacity and ability to generate early progenitors in long-term cultures of bone marrow and umbilical cord blood cells. We estimate that the CD34+ CD38- cells from a typical umbilical cord blood sample produce equivalent numbers of granulocyte erythrocyte macrophage megakaryocyte colony-forming units (CFU), twice as many granulocyte-macrophage (GM) CFU, and three times as many erythroid burst-forming units as the same population from an average bone marrow sample used in adult transplantation. These results suggest that umbilical cord blood is a suitable source of cells for adult transplantation.
Role of Toll-like receptor/MYD88 signaling in neurodegenerative diseases (2015)

Toll-like receptors (TLRs) are important innate immune proteins, and the activation of the TLRs results in the activation of intracellular signaling pathways, leading to the expression of proinflammatory cytokines that are essential to the identification and clearance of invading pathogens. TLR signaling occurs through adaptor proteins, most commonly myeloid differentiation primary response gene 88 (MyD88). It is now known that immune surveillance and inflammatory responses occur in neurodegenerative diseases and TLR/MYD88 signaling plays a critical role in these diseases. The included studies suggest a contribution for this signaling to the pathophysiology of Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple system atrophy, and related disorders. In this review, a discussion of the recent findings in this field is presented.
Low voltage fault detection and localisation using the TOPAS 1000 disturbance recorder (2005)

During the past 20 years an increasingly competitive power industry has recognised the importance of addressing the issue of power quality. Many companies now take an active roll in addressing the problems associated with power quality. They are investing in the research and development of equipment to overcome power dips, surges and interruptions, and offering the customer a wide and varied choice of solutions and services to their power quality needs. These solutions are usually based on overcoming the limitations of individual equipment, which is being used by the customer, rather than making improvement to the quality of power supplied.
Road-Holding: Braking and Traction - European Viewpoint (1970)

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Surface Modification of Ultrafine Magnetic Iron Oxide Particles (2002)

Ligand-exchange reactions between the caprylate units of capped γ-Fe2O3 nanoparticles, highly soluble in organic solvents, and multifunctional carboxylic compounds, like betaine·HCl and 2,5-dihydroxybenzoic acid, lead to reconstructed magnetic derivatives in which the magnetic properties of the inorganic support are combined with the chemical properties of the inserted ligands. Thus, the betaine derivative is highly hydrophilic, possessing interesting ion-exchange properties, while the 2,5-dihydroxybenzoate analogue inherits the recognition properties of its electron-rich aromatic constituent.
Results of a randomized, phase III trial of nab-paclitaxel (nab-P) and carboplatin (C) compared with cremophor-based paclitaxel (P) and carboplatin as first-line therapy in advanced non-small cell lung cancer (NSCLC). (2010)

LBA7511 Background: Platinum-based doublet therapy in NSCLC, regardless of the combination used, reached a therapeutic plateau. PC produced 15-25% overall response (ORR, Kelly 2001; Sandler 2006; Schiller 2002). Albumin-bound paclitaxel, nab-P, utilizes the albumin receptor (gp60)/caveolin-1 (CAV1) pathway achieving high intratumoral paclitaxel accumulation (Desai 2006), which may have contributed to a 48% ORR observed with nab-PC in NSCLC (Stroyakovsky, 2009). This phase III trial studied the efficacy of nab-PC vs. PC in advanced NSCLC of all histologic types. Methods: First-line stage IIIB or IV NSCLC pts (ECOG 0/1) were randomized to C AUC6 q3w and either nab-P 100 mg/m 2 qw w/o premed (n = 521) or P 200 mg/m 2 q3w with premed (n = 531). Primary endpoint: ORR by independent radiologic review (IRR). Results: Baseline and histologic characteristics were well balanced. Dose intensity of paclitaxel was higher in nab-PC vs. PC (82 vs. 65 mg/m 2 /wk). nab-PC was superior to PC both by IRR (33 vs. 25%, p=0.005), a 31% improvement (1.31 response ratio [RR], 95% CI: 1.08, 1.59), and by investigator review (37 vs. 30%, p=0.008), a 26% improvement (1.26 RR, CI: 1.06, 1.50). Histologic analysis showed significantly improved ORR for nab-PC (n = 228) vs. PC (n = 221) in squamous cell carcinoma (SQC) pts (41 vs. 24%, p<0.001, IRR), a 67% improvement (1.67 RR, CI: 1.26, 2.21). nab-PC was as effective as PC in nonSQC pts (ORR 26 vs. 25%). nab-PC was well tolerated, with significantly improved safety profile vs. PC despite higher paclitaxel dose delivered (1,338 vs. 1,100 mg/m 2 ). Conclusions: The primary endpoint was met, with significantly improved ORR and safety profile of nab-PC vs. PC as first-line therapy for advanced NSCLC. nab-PC was highly active in the SQC subset, which may in part be attributed to the aberrant CAV1 overexpression in SQC (Yoo 2003) and the high intratumoral accumulation of nab-P via the gp60-CAV1 pathway. [Table: see text] [Table: see text]
Protein Acetylation and Histone Deacetylase Expression Associated with Malignant Breast Cancer Progression (2009)

Overall, there was a global pattern of hypoacetylation associated with progression from normal to DCIS to IDC. These findings suggest that the reversal of this hypoacetylation in DCIS and IDC could be an early measure of HDAC inhibitor activity.
Security authentication of 3G-WLAN interworking (2006)

With the development of wireless Internet, the interworking of the third generation (3G) wide area wireless networks and wireless local area networks (WLAN) has become a focus of research. 3G systems have their advantages in charging management, roaming, and security facilities, and WLAN systems have the advantages of high bandwidth and low investment cost. Interworking of 3G-WLAN offers characteristics that complement each other perfectly. Several authentication protocols have been proposed to improve security. In this paper, we firstly introduce the architectures of 3G-WLAN interworking and discuss existing problems related to authentication and key agreement procedures. Then, we present two schemes by applying authentication based on EAP-TLS (extensible authentication protocol-transport layer security) and EAP-TTLS (tunneled TLS) into integrated 3G and WLAN to achieve high end-to-end security and authentication for the users. Finally, we conduct a series of performance evaluation on the energy consumption and latency of standard authentication protocols.
Glucagon-like peptide-1 modulates neuronal activity in the ratʼs hippocampus (1999)

In order to assess effects of glucagon-like peptide-1 (GLP-1) in the brain excluding the hypothalamus, the effects of GLP-1 (7-36) amide, a naturally produced active fragment, on the electroencephalogram and hippocampal single unit activities of anesthetized male Wistar rats were examined. I.c.v. injection of GLP-1 (7-36) amide decreased the hippocampal theta wave duration. Juxtacellular administration of GLP-1 (7-36) amide first increased and then decreased single unit activities recorded in the hippocampal CA1, which effects were antagonized by exendin (9-39) amide, a GLP-1 receptor antagonist, or 6-cyano-7-nitroquinoxaline-2,3-dione, a non-NMDA type glutamate receptor antagonist. These results indicate that GLP-1 receptors exist in the hippocampus and are involved in modulating hippocampal activity through an increase in the release of excitatory amino acid transmitters.
Correlation between methylation status of thep16/CDKN2 gene and the expression of p16 and Rb proteins in primary non-small cell lung cancers (1998)

In order to clarify the frequency of p16 gene inactivation and its relationship with Rb expression, immunohistochemical analysis of p16 and Rb proteins was carried out on 82 paraffin-embedded sections of primary non-small cell lung cancers (NSCLCs). From immunohistochemical results, abnormal p16 expression was observed in 66% of NSCLCs, 80% in squamous cell carcinomas and 46% in adenocarcinomas. An inverse correlation between p16 and Rb expressions was noted. Moreover, the methylation status of the p16 gene was investigated by the methylation-specific polymerase chain reaction (MS-PCR) using 29 frozen samples of NSCLCs. MS-PCR revealed the methylation of the p16 gene in 10(34%)of 29 NSCLCs. All NSCLCs exhibiting methylation exhibited abnormal p16 expression and were positive for Rb. In NSCLCs, no difference in methylation status was observed with respect to clinico-pathological characteristics including histological subtype and tumor stage. Our results demonstrate that abnormality of p16 expression is frequent in primary NSCLCs and methylation of the promoter of the p16 gene occurs in 34% of primary NSCLCs, which might play a significant role in the inactivation of the p16 gene.
Refractory two-dimensional hole gas on hydrogenated diamond surface (2012)

Use of two-dimensional hole gas (2DHG), induced on a hydrogenated diamond surface, is a solution to overcoming one of demerits of diamond, i.e., deep energy levels of impurities. This 2DHG is affected by its environment and accordingly needs a passivation film to get a stable device operation especially at high temperature. In response to this requirement, we achieved the high-reliability passivation forming an Al2O3 film on the diamond surface using an atomic-layer-deposition (ALD) method with an H2O oxidant at 450 °C. The 2DHG thus protected survived air annealing at 550 °C for an hour, establishing a stable high-temperature operation of 2DHG devices in air. In part, this achievement is based on high stability of C-H bonds up to 870 °C in vacuum and above 450 °C in an H2O-containing environment as in the ALD. Chemically, this stability is supported by the fact that both the thermal decomposition of C-H bonds and reaction between C-H bonds and H2O are endothermic processes. It makes a stark contrast to the instability of Si-H bonds, which decompose even at room temperature being exposed to atomic hydrogen. In this respect, the diamond 2DHG devices are also promising as power devices expectedly being free from many instability phenomena, such as hot carrier effect and negative-bias temperature instability, associated with Si devices. As to adsorbate, which is the other prerequisite for 2DHG, it desorbed in vacuum below 250 °C, and accordingly some new adsorbates should have adsorbed during the ALD at 450 °C. As a clue to this question, we certainly confirmed that some adsorbates, other than those at room temperature, adsorbed in air above 100 °C and remained at least up to 290 °C. The identification of these adsorbates is open for further investigation.
Fast singular value thresholding without singular value decomposition (2013)

Singular value thresholding (SVT) is a basic subroutine in many popular numerical schemes for solving nuclear norm minimization that arises from low-rank matrix recovery problems such as matrix completion. The conventional approach for SVT is first to find the singular value decomposition (SVD) and then to shrink the singular values. However, such an approach is time-consuming under some circumstances, especially when the rank of the resulting matrix is not significantly low compared to its dimension. In this paper, we propose a fast algorithm for directly computing SVT for general dense matrices without using SVDs. Our algorithm is based on matrix Newton iteration for matrix functions, and the convergence is theoretically guaranteed. Numerical experiments show that our proposed algorithm is more efficient than the SVD-based approaches for general dense matrices.
Improved Nutrient Absorption after Cimetidine in Short-Bowel Syndrome with Gastric Hypersecretion (1979)

MODERATE gastric hypersecretion is not uncommon after massive small-bowel resection,1 though it may be temporary.2 We speculated that, in patients with the short-bowel syndrome, increased duodenal acid and volume loads might impair digestion and absorption in the proximal gut. Cimetidine, a potent gastric antisecretory agent, might partially correct these abnormalities, allowing for greater efficiency of intraluminal digestion. The following studies in a patient with the short-bowel syndrome lend support to that speculation.Material and Methods Case report. A 36-year-old woman was seen because of massive steatorrhea (excretion of 18 g per day on a 20-g-fat diet), diarrhea (10 to . . .
Successful adoptive transfer and in vivo expansion of haploidentical γδ T cells (2014)

This pilot study shows that adoptive transfer and in vivo expansion of haploidentical γδ T lymphocytes is feasible and suggests a potential role of these cells in the treatment of haematological diseases.
Untersuchungen in der Homoisochroman‐Reihe (1970)

Abstract 1‐Brom‐homoisochroman ( 2b ) und dessen 4.4‐Dimethyl‐Derivat werden mit Hg(CN) 2 zu 1‐Cyan‐homoisochroman ( 2c ) bzw. 4.4‐Dimethyl‐1‐cyan‐homoisochroman ( 2f ) umgesetzt. Diese lassen sich in die zugehörigen Carbonsäuren ( 2g, h ), Carbonsäureester ( 2i ‐ m ) und Carbonsäureamide ( 2n, o ) sowie das Keton 2p überführen. ‐ Die Nitrile 2c bzw. 2f werden über ihre Carbanionen mit Alkyl‐, Acyl‐, Alkoxycarbonyl‐ oder Carbamoyl‐halogeniden an C‐1 zu Verbindungen von Typ 3 substituiert und daraus durch Hydrolyse die Carbonamide 4 erhalten. ‐ Die NMR‐Spektren, insbesondere der Abkömmlinge des 4.4‐Dimethyl‐homoisochromans, erlauben Schlüsse auf die Stereochemie des Siebenringes.
Human Face Super-Resolution Method Based on Train-Database (2012)

In this paper,we propose a human face super-resolution method based on training.This method composes similarity constrains of human face both in global and local manner.The local structure of human face ensures the solution of super-resolution to be in the space characterized by human face local structure.And the local structure in different scales instruct the searching to the optimal solution,then project the reconstructed face by local structure to the eigenface space determined by given human face database.Experiments show that the results have very good accuracy and high visual quality.
Decreased N‐acetylaspartate in motor cortex and corticospinal tract in ALS (1998)

The primary objectives of this study were to test whether 1) N-acetylaspartate (NAA), a neuronal marker, is reduced in motor cortex and corticospinal-tract (CST) brain regions of ALS patients; and 2) motor cortex NAA correlates to a clinical measurement of upper motor neuron function in ALS patients. Ten probable or definite ALS patients and nine neurologically normal control subjects were studied. Three axial planes of two-dimensional 1H MRSI data were collected, using a single spin-echo multislice sequence (TE140/TR2000). Two of the 1H MRSI planes were positioned superior to the lateral ventricles, and one plane was positioned at the level of the internal capsule. Spectroscopy voxels were selected from motor cortex, frontal cortex, parietal cortex, medial gray matter, centrum semiovale white matter, anterior internal capsule, and posterior internal capsule. Peak integrals were obtained for the three major 1H MRSI singlet resonances, NAA, creatine and phosphocreatine (Cr), and cholines (Cho). Maximum finger-tap rate was used as a clinical measurement of upper motor neuron function. In ALS, brain NAA/(Cho+Cr) was reduced 19% (p=0.024) in the motor cortex and 16% (p=0.021) in the CST (centrum semiovale and posterior internal capsule) regions. NAA/ (Cho+Cr) was not reduced in frontal cortex, parietal cortex, medial gray matter, or anterior internal capsule. There was a significant relation between ALS motor cortex NAA/(Cho+Cr) and maximum finger-tap rate (r=0.80; p=0.014). NAA/(Cho+Cr) was reduced in motor cortex and CST regions and unchanged in other brain regions of ALS patients when compared with controls. These findings are consistent with the known distribution of neuronal loss in ALS. The positive correlation between motor cortex NAA/(Cho+Cr) and maximum finger-tap rate suggests that reduced NAA/(Cho+Cr) is a surrogate marker of motor cortex neuron loss in ALS. These findings support the study of 1H MRSI NAA measurement as an objective and quantitative measurement of upper motor neuron dysfunction in ALS.
Role of ribavirin in HCV treatment response: now and in the future (2010)

Ribavirin is a drug which is essential to produce higher SVR rates both with Peg-IFN and HCV protease inhibitors currently in Phase III clinical trials. Thus, ribavirin is and will remain an important drug to achieving higher SVR rates in HCV infected persons.
Progress in Nanomedicine: Approved and Investigational Nanodrugs. (2017)

Nanomedicine is a relatively new and rapidly evolving field combining nanotechnology with the biomedical and pharmaceutical sciences.1-3 Nanoparticles (NPs) can impart many pharmacokinetic, efficacy, safety, and targeting benefits when they are included in drug formulations.1-5 Many nanodrugs have entered clinical practice, and even more are being investigated in clinical trials for a wide variety of indications.2 However, nanopharmaceuticals also face challenges, such as the need for better characterization, possible toxicity issues, a lack of specific regulatory guidelines, cost-benefit considerations, and waning enthusiasm among some health care professionals. 4,5 For these reasons, expectations regarding nanodrugs that are in early stages of development or clinical trials need to remain realistic.4.
On the equivalence of normalized convolution and normalized differential convolution (2002)

This paper establishes an algebraic relation between two methods recently reported; normalized convolution and normalized differential convolution. These are general methods for filtering incomplete or uncertain data and are based on the separation of both data and operator into a signal part and a certainty part. General filtering can be performed without preprocessing input data with an interpolation step. The methods allow both data and operators to be scalars, vectors or tensors of higher order. Normalized differential convolution has been used in a wide range of applications. Examples are estimation of gradient estimation in irregularly sampled data, estimation of differential invariants in sparse image flow fields and image edge effect reduction. It was previously shown that normalized convolution produces a description of the neighbourhood which is optimal in a least square sense. The algebraic relation to normalized differential convolution presented in this paper proves that the latter method is also optimal in the same sense as well.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Screening for Acute<i>I</i><sub>Kr</sub>Block Is Insufficient to Detect Torsades de Pointes Liability (2014)

Some but not all drugs designated as arrhythmogenic IKr blockers can generate arrhythmias by augmenting INa-L through the phosphoinositide 3-kinase pathway. These data identify a potential mechanism for individual susceptibility to proarrhythmia and highlight the need for a new paradigm to screen drugs for QT prolonging and arrhythmogenic liability.
Slicing the Onion: Anonymous Routing Without PKI (2005)

Abstract – Recent years have witnessed many proposals for anonymous routing in overlay peer-to-peer networks. To provide both sender and receiver anonymity, the proposed protocols require the overlay nodes to have public-private key pairs, with the public keys known to everyone. In practice, however, key distribution and management are well-known difficult problems that have crippled any widespread deployment of anonymous routing. In this paper, we propose a novel protocol that uses a combination of information slicing and source routing to provide anonymous communication similar to Onion Routing but without a public key infrastructure. 1
Quantitative Gas Chromatographic Sampler for Static Gaseous Reaction Systems. (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuantitative Gas Chromatographic Sampler for Static Gaseous Reaction Systems.E. R. AllenCite this: Anal. Chem. 1966, 38, 3, 527–528Publication Date (Print):March 1, 1966Publication History Published online1 May 2002Published inissue 1 March 1966https://pubs.acs.org/doi/10.1021/ac60235a053https://doi.org/10.1021/ac60235a053research-articleACS PublicationsRequest reuse permissionsArticle Views12Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Vapour-Liquid-Equilibrium of LNG (1969)

Methane, ethane and propane, the main components of LNG, have the property like ideal gas, but they deviate from ideal solution in multicomponent system by the effect of composition.Though it is essential to have correct equilibrium ratio to analyze the concentration process of LNG, we cannot find any adequate equations which estimate correctly the vapour-liquid equilibrium of the multicomponent system.We have obtained K values of the ternary system of methane, ethane and propane by observation, and studied the cases when a small quantity of butane is mixed in the system. Based on these data we analyzed the concentration process of LNG by calculating the equilibrium flash vaporization.
Improved Matrix-Filler Adhesion (1985)

Abstract Enhanced matrix-filler adhesion is realized after filler treatment with a surface treatment process. The hydrosol/coupling agent treatment was applied to a wide range of inorganic and organic fillers, and adhesion to a variety of matrix resins was improved. Scanning Electron Microscopy (SEM) was used to determine the locus of failure in the filled systems. The locus of failure shows the relative degree of adhesion between the filler and the polymer matrix. Significant improvement in adhesion in humid environments is also observed.