gebhart/patrepeval huggingface dataset:
Preventing Disc Brake Squeal using a Thin Plate Shim (2012)

Squealing from car disc brakes is a source of considerable discomfort and leads to customer dissatisfaction. The high frequency squeal noise above 1 kHz is very annoying and difficult to eliminate. Good braking performance against noise is considered to be a big market advantage. Reduction of brake squeal in the design stage is a formidable challenge that is faced by the automotive engineers. This paper attempts to provide a solution of eliminating disc brake squeal up to 10 kHz using a thin plate shim. First squeal occurrences in a disc brake assembly without thin plate shim are investigated for various operating conditions using a drag type brake dynamometer. Having identified the dominant squeal frequencies several shapes of thin plate shim are proposed and tested. The aim of using thin plate shims is to modify contact pressure distribution on the brake pads. A good shim should be able to effectively suppress and prevent those squeal frequencies generated in a disc brake system.
A 12-Month Clinical Study of LA-2585 (45.0 MG): A New 6-Month Subcutaneous Delivery System for Leuprolide Acetate for the Treatment of Prostate Cancer (2006)

LA-2585 (45.0 mg depot) consistently produced and maintained safe and effective serum testosterone suppression with total serum testosterone well below the medical castrate level of less than 50 ng/dl.
[Characteristics of chronic neuropathic pain and their relationship with psychological well-being in spinal cord injury patients]. (2007)

The results of this study show that NP appears frequently after SCI being more prevalent in patients who suffered the injury at more advanced ages. NP has a negative impact on the perception of psychological well-being.
A convenient and reproducible method to genetically transform bacteria of the genus Bifidobacterium (1996)

A protocol was developed for the introduction of foreign plasmid DNA into various Bifidobacterium strains. The method, which is applicable to all Bifidobacterium species tested so far, is based on electroporation of bacteria made competent by preincubation in electroporation buffer for several hours at 4 degrees C. Transformation of Bifidobacterium could be achieved with a plasmid vector originating from Bifidobacterium and with plasmid vectors from Corynebacterium, but not with vectors carrying replicons from Lactococcus or Lactobacillus.
Chemoenzymic synthesis and biological activity of both enantiomeric forms of tetraconazole, a new antifungal triazole (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemoenzymic synthesis and biological activity of both enantiomeric forms of tetraconazole, a new antifungal triazoleDaniele Bianchi, Pietro Cesti, Sandro Spezia, Carlo Garavaglia, and Luigi MirennaCite this: J. Agric. Food Chem. 1991, 39, 1, 197–201Publication Date (Print):January 1, 1991Publication History Published online1 May 2002Published inissue 1 January 1991https://pubs.acs.org/doi/10.1021/jf00001a040https://doi.org/10.1021/jf00001a040research-articleACS PublicationsRequest reuse permissionsArticle Views289Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Phytanic acid alpha-oxidation: accumulation of 2-hydroxyphytanic acid and absence of 2-oxophytanic acid in plasma from patients with peroxisomal disorders. (1992)

A stable isotope dilution method was developed for the measurement of 2-hydroxyphytanic acid and 2-oxophytanic acid in plasma. In plasma from healthy individuals and from patients with Refsum's disease, 2-hydroxyphytanic acid was found at levels less than 0.2 mumol/l, whereas the acid accumulated in plasma from patients with rhizomelic chondrodysplasia punctata, generalized peroxisomal dysfunction, and a single peroxisomal beta-oxidation enzyme deficiency. In plasma from both healthy controls and patients with peroxisomal disorders, 2-oxophytanic acid was undetectable. Four different groups of diseases were characterized with a defective phytanic acid alpha-oxidation and/or pristanic acid beta-oxidation: 1) Refsum's disease, with a defect at phytanic acid alpha-hydroxylation; 2) rhizomelic chondrodysplasia punctata, with a defect at 2-hydroxyphytanic acid decarboxylation; 3) generalized peroxisomal disorders, with defects at 2-hydroxyphytanic acid decarboxylation and at pristanic acid beta-oxidation; 4) single peroxisomal beta-oxidation enzyme deficiencies, with a defect at pristanic acid beta-oxidation, resulting in an impaired phytanic acid alpha-oxidation by inhibition. The results indicate that 2-hydroxyphytanic acid decarboxylation and pristanic acid beta-oxidation take place in peroxisomes.
New unorthodox semiconductor devices (1985)

A distinctive feature in the development of solid-state electronic devices has been the long time interval that has usually elapsed between the initial conception of the device, and its experimental realisation. The technology bottleneck which gives rise to this phenomenon has recently been significantly widened by the emergence of several new technologies which are enabling the realisation of device structures which, although not entirely new in concept, are receiving a revived interest because they are now technologically feasible. The author discusses a range of new device structures, many of which fall into the above category, and the ways in which new advances in technology have made them realistic contenders for many device applications. In addition a number of structures which rely upon entirely new phenomena are presented, with experimental demonstration considerably enhanced, and in some cases only made possible by the emergence of ion-implantation and molecular beam epitaxy.
Quasi-linear amplification using self-phase distortion compensation technique (1995)

This paper demonstrates a self-phase distortion compensation technique to realize linear power amplifiers, in which the positive phase deviation from a common-source FET and the negative phase deviation from a common-gate FET cancel each other. It is confirmed both theoretically and experimentally that increasing the drain-to-source conductance, G/sub d/, causes the self-phase distortion compensation effect. An experimental power amplifier for L-band personal communications systems, which employs the cascode connection, shows good phase deviation performance. More than 20-dB gain, 21-dBm output power, and 50% power added efficiency are obtained along with the adjacent channel interference of -52 dBc in 192-kHz bands at 600-kHz offset frequency from 1.9 GHz at the operating voltage of only 3 V. The demonstrated performances satisfy the specifications for the 1.9-GHz Japanese Personal Handy-phone System (PHS) utilizing the /spl pi//4-shift QPSK modulation scheme. The proposed technique is suitable for MMIC design, and allows the design of handsets that are small, lightweight, and have long operating times.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Technical set‐up and radiation exposure for standing computed tomography of the equine head (2014)

Summary The recent adaptation of human computed tomography ( CT ) machines to enable scanning of the equine head via standing sedation has revolutionised our ability to acquire images of this complex anatomical region. There are a small number of CT systems installed worldwide and it is to be expected that this will increase in the next few years; however, currently, there is no publication that describes the technical set‐up required to permit CT scanning of the equine head. This paper describes the technical set‐up, technique and exposures necessary to accomplish CT scanning of the horse under standing sedation to diagnose disorders of the equine head.
A secure private cloud storage system based on virtual isolation mechanism (2016)

Cloud storage technology is an important research orientation in cloud computing field. Due to privacy leakage and security problems, it is difficult for organizations holding core data (such as innovative enterprise and army) to extensively apply public cloud storage service. In this paper, a secure private cloud storage system VI-PCS based on virtual isolation mechanism is put forward. The system virtualizes physical storage media and public storage service to become virtual storage capacity, and services are provided for the system through centralized life cycle management. The system divides file storage process into metadata management, virtual storage of file and physical storage of file. Secure and reliable data storage is achieved through file renaming, IO transparent encryption and decryption. The system provides security network disk access method based on isolated sandbox technology, and data security, controllability and availability are guaranteed through virtual isolation environment. Besides, the system comes up with file bi-synchronization method based on ordered Hash Tree to achieve efficient data synchronization, and the offline mode also improves system availability and adaptation. The results indicate the system is superior in terms of reliability, security, scalability and adaptation.
Multicast routing with heterogeneous quality (2005)

In the common multicast problem, it is funda mental that destinations receive exactly the same information. In this paper, we examine the heterogeneous problem where destinations receive subsets of common information. It is worth noting that this scenario can be met in practice in audio and video sessions, as long as the data is encoded with the hierarchical encoding scheme. In this paper, we focus on the case where each destination requires a specific subset of the total information. For this problem, we design polynomial algorithms that meet some efficiency criteria. Theoretical and experimental work demon strates the advantage of the proposed algorithms over previous solutions.
A Three-Dimensional Cell Culture Method with a Micromesh Sheet and Its Application to Hepatic Cells (2018)

In vitro 3D cultures of hepatocytes are increasingly being used to assess human hepatic metabolism and toxicity in drug development. Here, we developed an in vitro 3D cell culture method with a microstructured mesh sheet and applied it to culturing human hepatoma HepG2 cells. The micromesh sheet is constituted of fine mesh strands and apertures that are each much larger than a single cell in size. Proliferating on a micromesh sheet, HepG2 cells spread out in a planar manner and then formed a multilayered cell sheet, so that cell-cell adhesion was dominant over cell-substrate adhesion as being different from 2D cultures. In micromesh cultures, the increase rate in thickness of the cell mass was visually slower than that in spheroid cultures, enabling us to clearly observe inside cells of the cell population by microscopy. Micromesh-cultured HepG2 cells showed higher viability compared with spheroid-cultured cells. The multilayered HepG2 cell sheet increased expression of hepatic marker genes and induced cell polarization with bile canalicular membranes. Furthermore, a combination of micromesh cultures with medium perfusion further induced expression of hepatic marker genes in HepG2 cells; especially CYP1A1 and CYP1A2 mRNA increased 86-fold and 43-fold compared with 2D controls, respectively, which were much higher than those in spheroid cultures. Thus, this simple and versatile micromesh culture method holds some advantages over traditional spheroid cultures and is expected to be instrumental in culturing more differentiated hepatic cells such as HepaRG cells and primary hepatocytes for future preclinical testing.
Experimental Chemotherapy and Toxicity in Mice of Three Mebendazole Polymorphic Forms (1987)

In an attempt to test the biological activity of three polymorphic forms of mebendazole (MBZ), called A, B and C, both the LD50 in mice after oral (p.o.) and intraperitoneal (i.p.) administration and the anthelmintic effect of these forms on the enteral and parenteral phases of the nematode Trichinella spiralis were studied. We observed that the polymorphic form A was the least toxic and effective against T. spiralis. The use of the polymorph C is advisable for oral treatment with MBZ in mice, having in mind its lower toxicity with regard to the polymorphic form B and its similar anthelmintic effects.
Fabrication and modeling of silicon-embedded high-<i>Q</i>inductors (2005)

In this paper, we report on the fabrication and modeling of a CMOS-compatible silicon-embedded high-Q integrated inductor (µH range). The fabrication process is based on DRIE, pulse-reverse super-conformal electroplating of copper and chemical–mechanical polishing. A lumped-element equivalent circuit model based on electromagnetic finite-element simulations for the determination of the element values was also developed. Inductors with different geometric design parameters were simulated to show the optimization possibility using the model. A Q-factor of over 60 (at 30–40 MHz) for a 2 µH inductor was measured, which is the highest reported in the literature for integrated inductors at such frequencies. The measurement results closely match the simulations from the lumped circuit model.
Antibiotic‐loaded chitosan film for infection prevention: A preliminary <i>in vitro</i> characterization (2010)

The growing infection rate by methicillin-resistant Staphylococcus aureus, especially with bone fracture fixation implants, is a major concern in extremity musculoskeletal wound treatment. This preliminary investigation evaluates the ability of chitosan film to be loaded with daptomycin and vancomycin in the operating room, in situ loading, and applied to musculoskeletal fixation devices to lessen or prevent infection. Films with 61, 71, and 80% degrees of deacetylation (DDA) made using lactic or acetic acid solvents were analyzed for their antibiotic uptake, elution, and activity along with film swelling ratio, ultimate tensile strength, Young's modulus, adhesive strength, and degradation. Chitosan films after 1 min of rehydration were able in a simulated, clinical setting to maintain mechanical integrity and adhesive strength to be applied to bone fracture fixation devices or implant surfaces. The film percent degradation increased with DDA increasing from 61 to 80%, but film degradation rate decreased in the presence of antibiotics. Eighty percent DDA chitosan films were optimal for absorbing and eluting antibiotics. Antibiotics eluted by the films were active against Staphylococcus aureus. These findings indicate that an 80% DDA chitosan film is potentially advantageous as a clinically adjunctive treatment in musculoskeletal injuries to lessen or prevent infections.
Selective Injection and Isolation of Ions in Quadrupole Ion Trap Mass Spectrometry Using Notched Waveforms Created Using the Inverse Fourier Transform (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelective Injection and Isolation of Ions in Quadrupole Ion Trap Mass Spectrometry Using Notched Waveforms Created Using the Inverse Fourier TransformManish H. Soni and R. Graham. CooksCite this: Anal. Chem. 1994, 66, 15, 2488–2496Publication Date (Print):August 1, 1994Publication History Published online1 May 2002Published inissue 1 August 1994https://pubs.acs.org/doi/10.1021/ac00087a013https://doi.org/10.1021/ac00087a013research-articleACS PublicationsRequest reuse permissionsArticle Views471Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The influence of dietary manipulation with n−3 and n−6 fatty acids on liver and plasma phospholipid fatty acids in rats (1986)

The interrelations between linoleic acid (LA) metabolites and fish oil fatty acids were studied. Sprague-Dawley rats (200-220 g) were fed a fat-free semisynthetic diet supplemented with 10% (by weight) of different combinations of evening primrose oil (EPO), a rich source of LA and gamma-linolenic acid, and polepa (POL), a marine oil rich in eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids. The combinations of supplement were as follows: 9% EPO-1% POL, 8% EPO-2% POL, 7% EPO-3% POL, 6% EPO-4% POL and 5% EPO-5% POL. After two weeks on the respective diets, the animals were killed, and the fatty acid compositions of liver and plasma phospholipids were examined. The results showed that animals fed higher proportions of POL consistently contained higher levels of dihomo-gamma-linolenic acid (DGLA) (p less than 0.05), a metabolite of LA and GLA, and lower levels of arachidonic acid (AA) (p less than 0.01), a metabolite of DGLA through delta-5-desaturation. Thus, an inverse relationship between AA/DGLA ratio and EPA levels was found to exist (r = -0.765 in plasma and -0.792 in liver). However, there was no such relationship between AA/DGLA ratio and DHA levels. This result suggested that EPA but not DHA in fish oil exerts an inhibitory effect on the conversion of DGLA to AA.
Fluorine toxicity in citrus: Growth retardation and leaf tip-burn accompanied increased fIuorine concentrations in experimentaI laboratory cultures (1955)

Foliage injury in certain fruit tree varieties has been reported as being quite serious when the leaves were subject to hydrogen fluoride or fluorine deposits. Leaf tip-burn resulted in gladiolus plants when exposure was made to various concentrations of fluorine gas. Leaves of citrus trees located in close proximity to gaseous sources of fluorine are reported as containing an increased content of fluorine. Fluorides are known to occur in certain crude phosphate materials, the very sources from which fertilizers are prepared.
Hydroxyapatite/Collagen Bone-Like Nanocomposite (2013)

Our group has succeeded to synthesize material with bone-like nanostructure and bone-like inorganic and organic composition via self-organization mechanism between them using simultaneous titration method under controlled pH and temperature. The hydroxyapatite/collagen (HAp/Col) bone-like nanocomposite completely incorporated into bone remodeling process to be substituted by new bone. Cells cultured on the HAp/Col revealed very interesting reactions. Osteoblast-like MG63 cells showed upregulation of alkaline phosphatase >3 times greater than MG63 cells cultured on tissue culture polystyrene (TCPS). MG63 cells 3-dimensionally cultured in a "HAp/Col sponge," a porous HAp/Col having sponge-like viscoelasticity, accumulated calcium phosphate nodules on extracellular matrices they secreted. Bone marrow cells co-cultured with osteoblasts on HAp/Col differentiated to osteoclasts without differentiation supplements. This phenomenon is not found in cells cultured on hydroxyapatite ceramics and TCPS, and rarely in cells cultured on dentin. These results suggest that HAp/Col is a good candidate for tissue engineering of bone as well as bone filler. In a clinical test as a bone filler, the HAp/Col sponge was significantly better than porous β-tricalcium phosphate. The HAp/Col sponge has been approved by the Japanese government and will be used as greatly needed bone filler in patients. In addition to the above, HAp/Col coating on titanium revealed higher osteo-conductivity than HAp-coated titanium and bare titanium and improved direct bonding between titanium and newly formed bone. The HAp/Col coating may be used for metal devices requiring osseointegration.
In-Process Inventories (1958)

Many manufacturing operations can be looked upon as chains of operations separated by inventories. In any real case, there is a question about how inventory investment should be balanced between these various in-process inventories. Investigation of this situation for a very general control system—the base-stock system—leads to some general results which enable one to answer this question by examining a (generally small) finite number of possibilities. The conclusion may be stated “The service time for any inventory should be zero”. An important corollary of the method is that it answers the question of what points in the manufacturing operation should be inventory points and what points should not.
Magnetically Excited Plasma Oxidation of GaAs (1996)

Relatively good-quality oxide of GaAs was grown using magnetically excited oxygen plasma (helicon wave) with substrate heating (300°C) or a mixture of Ar gas in oxygen. Post-thermal annealing at 400°C in oxygen substantially improved the capacitance-voltage ( C–V ) characteristics, which showed very small frequency dispersion without hysteresis. However, no inversion behavior was observed. X-ray photoelectron spectroscopic measurements showed that As 2 O 3 and Ga 2 O 3 are the main component species of these oxides.
Outage Performance of DF Network Coded (DFNC) Multi-User Cooperative Diversity in Orthogonal Uplink Channels (2010)

In this paper, we propose a Decode-and-Forward Network Coded (DFNC) multi-user cooperation scheme for orthogonal uplink channels in a wireless network. The network consists of m peers having independent information transmitting to a common destination. Each peer transmits its own data in the first time phase and serves as a relay in the second time phase to transmit the network coded information combining its own and others. Assuming block fading with independent fading coefficients, we evaluate the outage probability performance of the proposed scheme using high-SNR approximation. Particularly, we develop an upper bound on outage probability of DFNC, and compare it with Space-Time-Coded (STC) cooperation protocol and Repetition-based (REP) cooperation protocol. From theoretical analysis and numerical results, we show that the outage performance of proposed scheme outperforms both STC and REP at least in high-SNR region, regardless of total number of cooperating peers and provides diversity order of m + 1 in contrast with diversity order of m provided by STC and REP.