gebhart/patrepeval huggingface dataset:
Attribute-Based Signcryption Scheme with Non-monotonic Access Structure (2013)

The encrypted data presented by the traditional public key cryptosystem only provides the access control of nothing or all, that is, one can either decrypt the entire plaintext or nothing other than its length. Attribute-Based Signcryption provides not only the combined confidentiality and unforgeability, but also the chance that the participants access the cipher texts by their attributes instead of identities. The paper proposed a new attribute based signcryption scheme, which has the non-monotonic access structure and constant-size cipher text. The proposal supports the AND, OR, and NEG gate, and provides the more flexible access control and express ability. The security in confidentiality and unforgeability, are evaluated in the standard model under the q-DBDHE assumption. By employing the zero inner-multiplication, the length of the cipher text has no related with the number of attributes and lies in 5|G <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> |+|m| constantly. In additionally, the scheme could be verified publicly. It could be used in massive social network and makes the chance that sharing the data between communities.
Intracell Handover for Interference and Handover Mitigation in OFDMA Two-Tier Macrocell-Femtocell Networks (2010)

There are two main access policies (open and closed) to Femtocell Access Points (FAPs), being closed access the customers favorite. However, closed access is the root cause of crosstier interference in cochannel deployments of two-tier networks (i.e., macrocells and femtocells). Further, the effect of this problem is remarkably serious in the downlink of outdoor users not subscribed to any femtocell. Open access has been considered as a potential solution to this problem. However, this increases signaling in the network due to the elevated number of HandOvers (HOs) that mobile users have to perform. Therefore, this paper proposes an interference avoidance technique based on the use of Intracell HandOvers (IHOs) in Orthogonal Frequency Division Multiple Access (OFDMA) femtocells. It is shown that a proper combination of IHO and power control techniques reduces the outage probability for nonsubscribers compared with that of closed and open access. In addition, the impact of several network parameters such as the femtocell penetration is also considered in the analysis.
Expression of the L2 and E7 genes of the human papillomavirus type 16 in female genital dysplasias. (1992)

The expression of the E7 and L2 genes of HPV 16 was studied in benign and precancerous female genital lesions to evaluate their role in the development of dysplasias. Ninety biopsy specimens from 70 patients, selected on basis of dot blot DNA hybridization, were included in immunohistochemical and in situ hybridization analyses. In the HPV 16 DNA positive cases, L2 mRNA and E7 mRNA were detected in biopsies from 24 and 21 patients, respectively. L2 mRNA was found in eight of 16 cases of condyloma and mild dysplasia, and in 13 of 14 cases of moderate to severe dysplasia. The figures for E7 mRNA were 6/16 and 13/14, respectively. We found L2 mRNA in four of 12 normal or condylomatous specimens and E7 mRNA in only one of these. The detection rates for L2 and E7 mRNAs increased along with the severity of the lesions (P = 0.0064 and P = 0.0001, respectively). The L2 protein was found in one condyloma and in 12 dysplasias, eight of which were moderate or severe. The L2-antibody-reactive cells were localized in superficial layers of the epithelium. The detection rate for L2 mRNA and especially for E7 mRNA increased along with the histopathologic grade of the lesion.
Towards the smart construction site: improving productivity and safety of construction projects using multi-agent systems, real-time simulation and automated machine control (2012)

With the increasing complexity of construction projects grows the challenge of securing safety and achieving desirable productivity as the chief priorities of the construction industry. Addressing these issues requires robust mechanisms for on-site real-time data capturing, information processing and decision-making. The current research aims to further investigate the concept of the Smart Construction Site where workers, equipment, and materials are continuously tracked, and the collected information is processed in near real time to update the design model and the simulation of upcoming tasks, and to provide navigation guidance and safety warnings in case of potential collisions. The objective of our research is to improve the productivity and safety of heavy construction projects by integrating 3D design models (e.g. highway models) with the managerial and operational processes of heavy construction using advanced agent technology and multi-agent systems, real-time simulation, and automated machine control.
An exact formulation of the envelope function method for the determination of electronic states in semiconductor microstructures (1988)

In a recent letter (see ibid., vol.2, p.460 (1987)) the author outlined the first exact formulation of the envelope function method. In this paper the details of this new exact formulation are given. For clarity the discussion is carried out for the one-dimensional case. In previous approximate treatments coupling between envelope functions is mediated only by the action of the momentum operator on the periodic functions. It is shown that in the exact treatment, the action of the Hamiltonian operator on the periodic functions also introduces coupling between envelope functions and that this coupling is non-local in general. The nature of these new coupling terms is examined for an abrupt heterojunction. The relation between the new exact envelope function equations and previous work is discussed extensively. In particular, by making reasonable approximations to the new coupling terms, the author has managed to derive the effective mass equation for multilayer structures (particle in a box model in the quantum well case); the derivation sheds light on the vexed question of boundary conditions to be used in conjunction with this equation. The paradox of obtaining non-local envelope function equations from a local Schrodinger equation is also resolved.
Outlier Removal for Sparse 3D Reconstruction from Video (2008)

In this work, a comparative study on sparse metric 3D reconstruction from typical video content is presented. Experimental tests are performed in order to evaluate the performances of competing algorithms from the literature in several stages of 3D reconstruction, such as feature detection and epipolar geometry estimation. During the simulations, competing algorithms, such as SIFT and Harris corner detector, PROSAC and RANSAC, 7-point and 8-point algorithms, are tested on various video content, such as TV broadcasts or recording by a hand-held camera in a controlled environment. Based on these results, it could be concluded that SIFT yields significant improvements over Harris in terms of the quality of correspondences between frames, whereas RANSAC and PROSAC perform similarly for the case of limited outliers. Finally, 7-point algorithm yields slightly superior results over 8-point. In addition to this comparative study, a novel method for the elimination of erroneous points from the reconstructed scene is proposed. The quality of the resulting algorithm is quite acceptable for its 3D reconstruction.
[Psychomotor retardation in depression assessed by visuomotor tasks. Overview and achievements of ten years' research]. (2006)

Psychomotor retardation can play an important role in the diagnosis and treatment of depressive disorders.
A clinical phase I, pharmacokinetic (PK), and pharmacodynamic study of twice daily BIBF 1120 in advanced cancer patients (2005)

3031 Background: BIBF 1120 is a potent, orally available triple angiokinase inhibitor (VEGFRs, PDGFRs, FGFRs) that suppresses tumor growth by angiogenesis inhibition. After an initial study with once daily dosing in advanced cancer patients, twice daily (bid) dosing was performed in order to increase drug exposure without increasing toxicity. Methods: Treatment cycles consisted of 28 days continuous administration of BIBF 1120 bid followed by 7 days off. The dose was escalated until dose limiting toxicity (DLT) was observed. Further treatment cycles were allowed in the absence of progressive disease and persistent toxicity. PK profiles were obtained at the beginning and at end of the 1st cycle. Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) was performed at baseline, day 3, day 30, and after each further cycle. Results: 36 patients (5 female, 31 male) were included, 33 completed treatment cycle 1, and 3 patients were excluded due to unrelated adverse events (AE) or DLT. The dose was escalated according to the following scheme: 150 mg bid, 150+200 mg, 200 mg bid, 250 mg bid and 300 mg bid. Main drug-related AEs (mostly ≤CTC°2) were nausea, vomiting, and diarrhoea. Elevations of hepatic enzymes (LFT) were dose limiting (≥CTC°3) in 2/5 patients at 300 mg bid. 23/36 patients (64%) were treated for more than two cycles. 3 patients showed a partial tumor response at ≥200 mg bid (RECIST). In DCE-MRI, blood flow and permeability (IAUC60) in target lesions were reduced by ≥40% in 10/34 evaluable patients. BIBF 1120 exposure (AUC) displayed moderate to high variability. Maximum plasma concentrations were reached ∼3 hours after drug intake. BIBF 1120 was extensively distributed out of the blood and showed a high clearance with a mean terminal half-life of ∼15 h. Conclusions: As compared to once daily dosing, bid administration of BIBF 1120 allowed increased drug exposure to cancer patients without additional toxicity. AEs largely consisted of mild/moderate gastrointestinal toxicity. Reversible LFT elevations constituted DLT at 300 mg bid. Based on these results, 250 mg bid is considered the maximum tolerated dose of BIBF 1120. Encouraging signs of anti-tumor activity have been observed. Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Boehringer Ingelheim Boehringer Ingelheim Boehringer-Ingelheim
Highly Sensitive Methods Based on Seminested Real-Time Reverse Transcription-PCR for Quantitation of Human Immunodeficiency Virus Type 1 Unspliced and Multiply Spliced RNA and Proviral DNA (2008)

The effectiveness of highly active antiretroviral therapy (HAART), the standard of care for the treatment of human immunodeficiency virus type 1 (HIV-1) infection, is assessed by measuring the viral RNA load in plasma. A patient is considered to be successfully treated when the HIV-1 load in plasma stays below the detection limit of commercial assays. However, virus replication and evolution do continue in patients under HAART, which may eventually result in the development of drug-resistant HIV-1 strains and therapy failure. To monitor this low-level virus replication in peripheral blood mononuclear cells (PBMC), sensitive methods are required to measure HIV-1 molecular markers. We report the development of highly sensitive methods for the quantitation of unspliced and multiply spliced HIV-1 RNA and proviral DNA in PBMC. The methods are based on innovative seminested real-time reverse transcription-PCR (RT-PCR) that combines the accuracy and precision of real-time PCR and the sensitivity of nested PCR. We show that the newly developed methods are superior to the conventional single-step real-time RT-PCR in their sensitivity, accuracy, dynamic range, and the power of quantitative detection of HIV-1 RNA and DNA in clinical samples. These easy-to-perform methods can be widely used in research, including clinical studies, to monitor intracellular processes of virus replication.
Real Options in Law: (Possibly, Frivolous) Litigation and Other Applications (2003)

This Article advances the thesis that real options are not only ubiquitous in law, but also provide novel insights about legal decision making, doctrines and rules. An introduction provides a brief a primer about financial options, real options, and real options in law. Part I of this Article develops implications of the fact that every lawsuit contains a sequence of real options for the plaintiff to unilaterally abandon that lawsuit. Part II of this Article appraises the limitations of game-theoretic analysis of the abandonment options embedded in litigation and some responses to such limitations. Part III of this Article illustrates how to apply real options analysis to provide insights over numerous legal areas, including the “calculus” of negligence and the Hand formula; collateral estoppel and res judicata; constitutional amendments; judicial minimalism; and marriage or divorce statutes. A conclusion summarizes the insights of the novel real options approach to law advanced in this Article. An appendix develops a general mathematical sequential real abandonment options game-theoretic model of (possibly, frivolous) litigation. This analytical model demonstrates how the real abandonment option values in (possibly, frivolous) litigation determine a set of necessary and sufficient conditions for the sequential credibility of (possibly, frivolous) litigation and derives Nash equilibrium settlement values.
Visual stimulator (1978)

An easily portable apparatus for flicker fusion experiments is described. It uses crossed polarizers to produce modulated beams and a light guide made of optical fibers to mix these beams for producing a sinusoidally modulated stimulus of which the frequency, the modulation amplitude, the luminance, the color adaptation light, and the field size can be varied independently.
A Novel Epsilon Near Zero Tunneling Circuit Using Double-Ridge Rectangular Waveguide (2014)

In this paper, an epsilon near zero (ENZ) tunneling circuit using a double-ridge rectangular waveguide (RWG) is proposed for the miniaturization of a waveguide component. The proposed ENZ channel and is located in the middle of the input-output RWG (IORWG). The ratio of the height to the width of the channel waveguide is very small compared to the IORWG. By properly adjusting the ridge dimensions, the tunneling frequency of the proposed ENZ channel can be lowered to near the cut-off frequency of the IORWG. For the proposed ENZ tunneling circuit, the approach adopted for extracting the effective permittivity, effective permeability;normalized effective wave impedance, and propagation constant from the simulated scattering parameters was explained. The extracted parameters verified that the proposed channel is an ENZ channel and electromagnetic energy is tunneling through the channel. Simulation and measurement results of the fabricated ENZ channel structure agreed.
Mysterious oligomerization of the amyloidogenic proteins (2010)

Misfolding and subsequent self-assembly of protein molecules into various aggregates is a common molecular mechanism for a number of important human diseases. Curing protein misfolding pathologies and designing successful drugs for the inhibition or reversal of protein aggregation depends on understanding the peculiarities of the misfolding process. Protein aggregation is a very complex process characterized by a remarkable polymorphism, where soluble amyloid oligomers, amyloid fibrils and amorphous aggregates are found as final products. This polymorphism is associated with the existence of multiple independent and competing assembly pathways leading to aggregation. Regardless of the aggregation mechanism, soluble oligomers are inevitably formed during the self-association process. Some of these oligomers are now considered to be major initiators of the neurodegenerative cascades of corresponding diseases. However, not all oligomers are equally harmful, and several amyloidogenic proteins have been shown to form nontoxic oligomers, some of which were efficient fibrillation inhibitors. Unfortunately, the information on the structural properties of soluble oligomers and the mechanisms of their formation, interconversion and toxicity is sparse. This review provides an overview of some topics related to soluble oligomers and represents several illustrative examples of toxic, nontoxic, productive and off-pathway amyloid oligomers.
Superanuation: SMSF trustee dealings with the ATO - how to handle contraventions (2013)

The ATO has several options to deal with contraventions of superannuation law by the trustee of a self managed superannuation fund. A consistent theme throughout these options, however, is the importance of the dealings of the trustee in relation to a contravention. This article provides some insights.
Interaction of Curcumin and Bixin with β-Cyclodextrin: Complexation Methods, Stability, and Applications in Food (2011)

This work aimed to compare methods for the formation of complexes of bixin and curcumin with β-cyclodextrin (β-CD) and to evaluate the stability of the complexes formed by these methods and their food applications. The stoichiometric relationship between curcumin and β-CD was 1:2 and that between bixin and β-CD was 1:1. Curcumin-β-CD and bixin-β-CD complexes formed by kneading, coprecipitation, and simple mixing were evaluated by differential scanning calorimetry (DSC), thermogravimetry analysis (TGA), or nuclear magnetic resonance (NMR-H). For both curcumin and bixin, the best method of complexation was coprecipitation. Complexation of colorants with β-CD promoted an intensification of color and increased water solubility; however, stabilization in the presence of light occurred only for bixin. Application of curcumin-β-CD in cheese and yogurt and bixin-β-CD in the curd did not alter the initial characteristics of the products, which were sensorialy well accepted. Therefore, the complexation of these natural colorants with β-CD favors their use in low-fat foods, broadening the field of industrial application.
Concanavalin A (NSC-143504): its action on experimental tumor cells and possible use in cancer chemotherapy. (1975)

Concanavalin A administered to mice kills KHT fibrosarcoma tumor cells and, less markedly, AKR lymphoma cells at doses where it has no effect on numbers of normal hematopoietic colony-forming cells. Concanavalin A in vitro agglutinates suspensions of cells prepared from murine and human tumors but does not agglutinate suspensions prepared from most normal mouse tissues. In spite of its selective action against tumor cells at the cellular level, the possibilities for using concanavalin A therapeutically are limited by its unusual toxicity, a generalized vasculitis that is seen in the mouse, monkey, and pig at approximately the same dose level.
Adaptive Multimodal Exploration Of Music Collections. (2009)

[TODO] Add abstract here.
Keratinocyte growth factor and its receptor are involved in regulating early lung branching (1996)

ABSTRACT Lung branching morphogenesis depends on mesenchymalepithelial tissue interactions. Keratinocyte growth factor (KGF) has been implicated to be a regulator of these tissue interactions. In the present study, we investigated the role of KGF in early rat lung organogenesis. Reverse transcriptase-polymerase chain reaction analysis revealed KGF mRNA expression in the mesenchymal component of the 13-day embryonic lung, while message for KGF receptor (KGFR) was expressed in the epithelium, confirming the paracrine nature of KGF/KGFR axis. Antisense KGF oligonucleotides inhibited DNA synthesis of embryonic lung explants. This inhibitory effect of antisense KGF was partially reversed by the addition of exogenous KGF. Recombinant KGF was mitogenic for 13-day isolated embryonic lung epithelial cells. Medium conditioned by 13-day lung mesenchymal cells also stimulated DNA synthesis of 13-day embryonic lung epithelial cells. This stimulatory effect was partially abrogated by a neutralizing KGF antibody. The number of terminal buds of lung explants cultured in the presence of antisense KGF oligonucleotides was significantly reduced compared to control explants. Exogenous KGF partially abrogated the inhibitory effect of antisense KGF on early lung branching. Sense or scrambled KGF oligonucleotides had no inhibitory effect on lung growth and branching. Addition of neutralizing KGF antibodies to the explants also reduced the degree of branching, while non-immune IgG and neutralizing acidic FGF antibodies had no effect. Explants incubated with antisense oligonucleotides targeted to the initiation site of translation of both the splice variants of the fibroblast growth factor receptor-2 (FGFR2) gene, KGFR and bek, exhibited a similar reduction in lung branching as observed with antisense KGF oligonucleotides. Antisense KGFR-specific oligonucleotides dramatically inhibited lung branching, while exposure of explants to antisense bek-specific oligonucleotides resulted in reduced branching albeit to a lesser degree than that observed with antisense KGFR-specific oligonucleotides. Neither sense nor scrambled KGFR-specific oligonucleotides had any effect on early lung branching. These results suggest that the KGF/KGFR system has a critical role in early lung organogenesis.
Interaction of human cytomegalovirus with p53: possible role in coronary restenosis. (1995)

Restenosis occurs in 25-50% of patients. Within 1-6 months after coronary angioplasty, excessive injury-induced smooth muscle cell (SMC) proliferation contributes to the development of restenosis; its causes remain unknown. The results of this study implicate human cytomegalovirus (HCMV) and HCMV-induced abnormalities in p53 function in the restenosis process. Almost 40% of restenosis lesions, obtained by atherectomy, demonstrated increased SMC p53 levels by p53 immunopositivity; sequencing revealed the p53 to be the wild type. A strong correlation was found between p53 immunopositivity and the presence of HCMV DNA. Moreover, the HCMV IE84 protein co-immunoprecipitates with p53, and p53 transcriptional capacity is reduced by IE84. Thus, HCMV may play a causal role in restenosis, which may be at least partly mediated by inhibiting p53 suppressor effects.
Licensing security (2012)

There exist legal structures defining the exclusive rights of authors, and means for licensing portions of them to others in exchange for appropriate obligations. We propose an analogous approach for security, in which portions of exclusive security rights owned by system stakeholders may be licensed as needed to others, in exchange for appropriate security obligations. Copyright defines exclusive rights to reproduce, distribute, and produce derivative works, among others. We envision exclusive security rights that might include the right to access a system, the right to run specific programs, and the right to update specific programs or data, among others. Such an approach uses the existing legal structures of licenses and contracts to manage security, as copyright licenses are used to manage copyrights. At present there is no law of “security right” as there is a law of copyright, but with the increasing prevalence and prominence of security attacks and abuses, of which Stuxnet and Flame are merely the best known recent examples, such legislation is not implausible. We discuss kinds of security rights and obligations that might produce fruitful results, and how a license structure and approach might prove more effective than security policies.
Modelling association football scores (1982)

Abstract Previous authors have rejected the Poisson model for association football scores in favour of the Negative Binomial. This paper, however, investigates the Poisson model further. Parameters representing the teams' inherent attacking and defensive strengths are incorporated and the most appropriate model is found from a hierarchy of models. Observed and expected frequencies of scores are compared and goodness‐of‐fit tests show that although there are some small systematic differences, an independent Poisson model gives a reasonably accurate description of football scores. Improvements can be achieved by the use of a bivariate Poisson model with a correlation between scores of 0.2.