gebhart/patrepeval huggingface dataset:
This issue (2012)

This issue George Brosi Breece D'J Pancake remains an amazing phenomenon of American as well as Appalachian Literature. He authored only one book, The Stories of Breece D'J Pancake published posthumously in 1983. It remains not only in print, but a brisk seller. We are proud to make him the featured author of this issue of Appalachian Heritage, and are eternally grateful to John Casey, his literary executor, for his cooperation and permission to reprint Pancake's works, carefully preserved in the archives of both the University of Virginia and West Virginia University Libraries. We are indeed deeply grateful to these libraries as well for allowing us permission to reprint. The stories in Pancake's book remain his most impressive, most mature work, and we recommend that this magazine be read in conjunction with them. Despite the fact that Pancake's work published here is not as well-developed as his later work, we feel that this magazine helps readers to obtain a deeper feel for his life and work and appreciation for his contribution. We are grateful to Grace Toney Edwards, who was a friend of Breece Pancake when they were both graduate students at the University of Virginia, for being our guest editor and to Phyllis and Jim Moore, who, along with Grace Edwards and her husband, John C. Nemeth, gathered the photos we are using in this issue. Thanks as well to Thomas E. Douglass, the author of the only book about Breece D'J Pancake, A Room Forever: The Life, Work and Letters of Breece D'J Pancake, for photos and his help in putting this issue together as well as for his article here. Thanks to Ann Pancake, David "Woody" Wilson, B. R. Seybert, Donna Ogle, and Lee Johnson for their important commentary on Breece D'J Pancake also prepared especially for this issue. We are proud to have an original story in this issue, "The Reunion," from Robert Morgan, one of the most distinguished contemporary regional writers. Our poets range from the widely published David Huddle and R. T. Smith, to Amy Partin-Elliott whose first published poem appears here. Hadley Hury and Kathy Whitson have not previously published in this journal, but Charles Swanson has contributed to previous issues. We are proud to include a review by Tricia Shapiro of Transforming Places: Lessons from Appalachia by Stephen L. Fisher and Barbara Ellen Smith, an important book about social movements in our region. [End Page 9] Copyright © 2012 Berea College
How to Reap Higher Profits With Dynamic Princing (2007)

Dynamic pricing, in which prices respond to supply and demand pressures in real time or near-real time, has long been used by airlines and hotels. Now dynamic pricing is making inroads in many different sectors including apparel, automobiles, consumer electronics, personal services, telecommunications and second- hand goods. These companies are making use of new findings on dynamic pricing and of increases in data-processing power to raise their average realized prices, thereby increasing revenues and profits.

There are two mechanisms for dynamic pricing: posted prices that customers can see; and price-discovery mechanisms, in which customers determine prices through their own actions. These two mechanisms are employed in seven different forms: yield management (commonly used by airlines), demandbased pricing, three types of auctions, group buying and negotiations. The article describes eight situations for using the various forms of dynamic pricing. An important constraint in employing dynamic pricing is consumers? Latitude of Price Acceptance, which varies for different products and situations and which can be discovered through observation, surveys or analysis of demand elasticities. Customer participation in the pricing process decreases the chances of a consumer backlash. Customers also tend to embrace dynamic pricing in the following situations: where the price reflects intensity of demand for the product, there is communication between the seller and the consumer, and the price difference is explained by a difference in perceived value across channels through which the transaction occurred. The more the seller understands the buying cycles and habits of the customer, the more he is able to manage price margins to the rhythm of the customer?s shopping, to segment customers and to develop price discrimination.
<i>Borrelia burgdorferi</i> RevA Antigen Binds Host Fibronectin (2009)

Borrelia burgdorferi, the Lyme disease-causing spirochete, can persistently infect its vertebrate hosts for years. B. burgdorferi is often found associated with host connective tissue, where it interacts with components of the extracellular matrix, including fibronectin. Some years ago, a borrelial surface protein, named BBK32, was identified as a fibronectin-binding protein. However, B. burgdorferi BBK32 mutants are still able to bind fibronectin, indicating that the spirochete possesses additional mechanisms for adherence to fibronectin. We now demonstrate that RevA, an unrelated B. burgdorferi outer surface protein, binds mammalian fibronectin in a saturable manner. Site-directed mutagenesis studies identified the amino terminus of the RevA protein as being required for adhesion to fibronectin. RevA bound to the amino-terminal region of fibronectin. RevA binding to fibronectin was not inhibited by salt or heparin, suggesting that adhesin-ligand interactions are primarily nonionic and occur through the non-heparin-binding regions of the fibronectin amino-terminal domains. revA genes are widely distributed among Lyme disease spirochetes, and the present studies determined that all RevA alleles tested bound fibronectin. In addition, RevB, a paralogous protein found in a subset of B. burgdorferi strains, also bound fibronectin. We also confirmed that RevA is produced during mammalian infection but not during colonization of vector ticks and determined that revA transcription is controlled through a mechanism distinct from that of BBK32.
SMP and embedded real-time (2007)

With the advent of multithreaded/multicore CPUs, even embedded real-time applications are starting to run on SMP systems -for example, both the Xbox 360 and PS/3 are multithreaded, and there even have been SMP ARM processors! As this trend continues, there will be an increasing need for real-time response from SMP systems. Because not all embedded systems vendors will be willing or able to create or purchase SMP real-time operating systems, we can expect that a number of them will make use of Linux. Because of this change, a number of real-time tenets have now become myths. This article exposes these myths and then discusses some of the challenges that Linux is surmounting in order to meet the needs of this new SMP-real-time-embedded world.
Nitriles from aldoximes. New reaction of phosphonitrilic chloride (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNitriles from aldoximes. New reaction of phosphonitrilic chlorideGoffredo Rosini, Graziano Baccolini, and Sandro CacchiCite this: J. Org. Chem. 1973, 38, 5, 1060–1061Publication Date (Print):March 1, 1973Publication History Published online1 May 2002Published inissue 1 March 1973https://pubs.acs.org/doi/10.1021/jo00945a048https://doi.org/10.1021/jo00945a048research-articleACS PublicationsRequest reuse permissionsArticle Views177Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update (2010)

To date, molecular genetic analyses have identified over 500 distinct DNA variants in five disease genes associated with familial Parkinson disease; alpha-synuclein (SNCA), parkin (PARK2), PTEN-induced putative kinase 1 (PINK1), DJ-1 (PARK7), and Leucine-rich repeat kinase 2 (LRRK2). These genetic variants include approximately 82% simple mutations and approximately 18% copy number variations. Some mutation subtypes are likely underestimated because only few studies reported extensive mutation analyses of all five genes, by both exonic sequencing and dosage analyses. Here we present an update of all mutations published to date in the literature, systematically organized in a novel mutation database (http://www.molgen.ua.ac.be/PDmutDB). In addition, we address the biological relevance of putative pathogenic mutations. This review emphasizes the need for comprehensive genetic screening of Parkinson patients followed by an insightful study of the functional relevance of observed genetic variants. Moreover, while capturing existing data from the literature it became apparent that several of the five Parkinson genes were also contributing to the genetic etiology of other Lewy Body Diseases and Parkinson-plus syndromes, indicating that mutation screening is recommendable in these patient groups.
Organic Syntheses by Means of Noble Metal Compounds (1967)

パラジウムーオレフィン錯体とカルバニオンの反応による新しい炭素一炭素結合の生成を検討した。π一アリル錯体は活性メチレン化合物,エナミンと容易に反応して炭素一炭素結合を生成した。シクロオクタジエソパラジウム錯体もマロン酸エステルが導入された錆体を生成し,この錯体と塩基との反応によって8員環にマロン酸エステルが付加した種々の化合物が得られた。 パラジウム－オレフィン錯体は一酸化炭素とベンゼン中で反応し,3一クロルカルボン酸塩化物になった。さらにオレフィンのカルボニル化反応が,触媒量の金属パラジウムとハロゲン化水素との触媒作用によってアルコール中で容易に進行し,飽和カルボン酸エステルが生成することを見いだした。オレフィンと一酸化炭素と水素とからは収率は低いがアルデヒドが生成する。このような金属パラジウム触媒によるオレフィンのツルポニル化反応の機機を提出したが,さらにこの反応機構から考えて,金属パラジウムによるア.ルデヒド,酸ハ資ゲソ化物の脱カルボニル反応を予想し,実験的にこれを確かめた。またとれに関連してRosenmund還元の機構を提出した。これらの化合物の脱カルボニル反応はクロロトリス(トリフェニルボスフィン)ロジウム(I)を使用すると室温でも進行することがわかった。酸ハロゲソ化物のこの錯体に対する酸化的付加反応によって, 脱カルポニル反応の中間体と考えられる新しいアシルロジウム錯体を単離した。クロ群カルボニルピス(トリフェニルポスフィン)ロジウム(1)は酸ハロゲン化物の触媒的脱・カルボニルに有効に使用できることがわかった。この触媒はとくに芳香族カルボン酸ハロゲン化物から芳香族ハロゲン化物をつくるのに有効である。パラジウム触媒を用いるカルボニル化反応は単純オレフィンのみならず,他の二重, 三重結合にも応用できる。アリル型化合物,共役ジエンからはβ,γ -不飽和エステルが生成した。このようにして,生成したβ,γ-不飽和エステルは塩化パラジウム(I)と反応して新しいアリル錯体を生成することを見いだした。パラジウム,塩化水素系はアセチレン類のすぐれたカルボニル化触媒にもなる。ジフェニルアセチレン,アセチレンモノおよびジカルボン酸エステル,プロパルギル型化合物も容易にカルボニル化された。パラジウム触媒によるカルボニル化反応の特長はジカルボニル化が主反応として起ることである。アミンも金属パラジウムの存在下で一酸化炭素と反応し,尿素,ホルムアミド, オキザミドの各誘導体を生成することを見いだした。
An iterative method for mixed H/sub 2//H/sub ∞/ synthesis via static output-feedback (2003)

The mixed H/sub 2//H/sub /spl infin// problem is an open problem whose closed-form solution is not known except for special cases presented in the literature. After the problem definition and a short survey of some general existing results, a new sufficient condition for the mixed synthesis problem via static output feedback is proposed. This new sufficient condition relies on the introduction of new extra variables leading to the use of two different Lyapunov functions. This allows us to reduce the conservatism of the usual existing conditions. A coordinate-descent based iterative numerical procedure is used to compute local optimal solutions of the initial problem. The relevance of this approach is illustrated by a numerical example.
Development and Use of a Lithium-Metal Reference Electrode in Aging Studies of Lithium-Ion Batteries (2014)

The development and implementation of an in situ lithium-metal reference electrode for use in lithium-ion cells is described. The reference electrode is inserted into cylindrical, commercially available 1.2 Ah lithium-ion cells via perforation of the cell's outer metallic casing. The reference electrode is used to investigate voltage characteristics of the individual electrodes throughout calendar (i.e., zero duty) aging and duty cycle aging regimes. The response of the electrode voltages (vs. reference) to a given current pulse prior to and during interruptions of the aging regime indicates that the resistance of the positive-electrode is much larger than that of the negative electrode. Prior to aging, the ratio of the positive electrode resistance to that of the negative electrode is approximately two. After aging, the resistance of the positive electrode nearly triples, resulting in a ratio of approximately six, with the resistance of the negative electrode remaining approximately unchanged for both calendar- and cycle-aging regimes. The changes in the cell's coulombic capacity at various discharge rates are also characterized and indicate the additional contribution of cycle aging over the calendar aging alone to the capacity loss of cells. Furthermore, both "charge depletion" and "charge sustaining" cycle aging were investigated and indicates the added stress of charge depletion operation.
Synthesis of Vicinal Diamino-<i>endo, cis</i>-Norbornene Derivatives (2011)

Abstract The synthesis of 2,3-disubstituted-endo,cis-norborn-5-ene derivatives is described. Cyclic ureas and cis vicinal diamines substituted with p-tolyl and perfluorophenyl rings were prepared. The use of potassium carbonate as an innocuous CO source for the formation of a cyclic urea was demonstrated.
Dynamic Omnidirectional Vision For Mobile Robots (1985)

Mobile robotic devices hold great promise for a variety of applications in industry. A key step in the design of a mobile robot is to determine the navigation method for the mobility control. The purpose of this paper is to describe a new algorithm for omnidirec-tional vision navigation. A prototype omnidirectional vision system and the implementation of the navigation techniques using this modern sensor and an advanced automatic image processor is described. The significance of this work is in the development of a new and novel approach - dynamic omnidirectional vision for mobile robots and autonomous guided vehicles.
Integration and control of an induction-coupled plasma system and facility (1995)

Plasma systems have been used for a number of industrial and aerospace applications over the last 35 years. Recent efforts to remediate environmental problems are increasing the number of applications. A proprietary process known as Plasma Energy Recycle and Conversion (PERC{trademark}) is being developed by Plasma Technology, Inc. of Santa Fe, NM, to eliminate waste material cleanly and efficiently. This process uses a radio frequency (RF) induction-coupled plasma (ICP) system to heat a thermal reactor to high temperatures for this purpose. The principle components of this facility include the RF heater and a vacuum tube power supply, a modular thermal reactor, auxiliary support equipment such as vacuum, cooling water and gaseous supply systems, controls, instrumentation and data acquisition systems. This paper provides an overview of the Sverdrup-provided or modified facility design requirements and principle systems and components.
Arynes and Cyclohexyne in Natural Product Synthesis (2012)

This Minireview highlights recent advances in the field of aryne and cyclohexyne chemistry that have allowed the extraordinary reactivity of these entities to be harnessed during the course of natural product syntheses. The syntheses presented rely on the use of these reactive species in chemoselective transformations and follow unprecedented synthetic strategies that are inspiring for the practitioners of synthetic organic chemistry.
Regenerating Blood Vessels (2011)

Maintaining coronary artery blood flow and myocardial perfusion is critically important for the survival and function of cardiac muscle. Stem cells can contribute to the generation and maintenance of vascular networks that support the myocardium either directly, as a source of new vascular cells, or indirectly, by secreting soluble factors to promote angiogenesis. In addition to generating microvascular networks, stem cells are increasingly being used to create transplantable replacement arteries for coronary artery bypass grafting, the standard of care for surgical cardiac revascularization. This chapter reviews current progress in blood vessel tissue engineering, sources of stem cells for vascular graft synthesis, and opportunities and challenges associated with using stem cells to create blood vessel substitutes for clinical applications.
Neumonía grave en terapia intensiva (2004)

Se realizo un estudio descriptivo de 59 pacientes en la UCI del Hospital Pediatrico Universitario “Dr. Eduardo Agramonte Pina”, Camaguey, para analizar el estado de la neumonia grave, entre enero de 2001 y diciembre de 2002. Las variables analizadas fueron: grupos de edades, sexo, procedencia de la neumonia, factores de riesgo, enfermedad previa, complicaciones, germenes aislados, terapia antimicrobiana inicial, ventilacion mecanica, estadia y mortalidad. Se utilizo el programa estadistico MICROSTAT. Los grupos etareos con mas afectados fueron los de menores de 1 ano y de 1 a 5 anos (38.9% en ambos casos), y con predominio del sexo masculino (62.71%). La neumonia comunitaria resulto significativa (93,2%). La presencia de irritantes ambientales constituyo un factor de riesgo frecuente (52.5%). Las complicaciones afectaron significativamente a los menores de un ano y el derrame pleural fue la mayor complicacion pulmonar, seguida de la sepsis. Los germenes aislados mas frecuentemente fueron el neumococo, el Staphylococcus aureus y el S. epidermidis . En los pacientes con evolucion favorable predomino la terapia antimicrobiana protocolizada y la estadia entre 5 y 10 dias. Un reducido grupo recibio soporte ventilatorio. La mayoria de los pacientes egresaron vivos.
Pyridin‐Verbindungen aus Etacrynsäure, 2. Mitteilung (1992)

Abstract Ausgehend vom Nicotinsäuremethylester 2 werden das Nicotinamid 4 , die 5‐Hydroxymethyl‐Verbindung 5 und über fünf Stufen das 5,6‐Bis(hydroxy‐methyl)pyridin 10 hergestellt. Das N ‐Oxid 3 reagiert mit Salpetersäure zum Nitroaromaten 11.
Time-Weighted LSTM Model with Redefined Labeling for Stock Trend Prediction (2017)

Various techniques have been applied to predict stock market trends. However, the results are not quite satisfactory due to stock market's complexity. Many approaches either lack a clear and reasonable definition of trend or neglect the uniqueness of time attribute in stock data, treating them like other attributes, and use one-size-fits-all models to solve such a typical time-series problem. In this paper, we attempted to exploit the time attribute of stock data to improve prediction accuracy. Firstly, instead of treating data indiscriminately, we used time weight function to carefully assign weights to data according to their temporal nearness towards the data to be predicted. Secondly, the stock trend definitions were formally given by referencing financial theories and best practices. Lastly, Long Short-Term Memory (LSTM) network was customized to discover the underlying temporal dependencies in data. The trials of different time-weighted functions showed that the relation between the importance of data and their time-series is not constant. Instead, it falls within linear and quadratic, roughly a quasilinear function. Equipped with the time-weighted function, LSTM outperformed other models and can be generalized to other stock indexes. In the test with CSI 300 index, we achieved 83.91% in accuracy when fed with the redefined trends.
DEVELOPMENTS IN INTELLIGENT TUTORING SYSTEMS 2010-2020 (2020)

Intelligent Tutoring Systems (ITS) vary a lot in the architecture employed, the realization of domain knowledge,
the student modelling techniques, the pedagogical techniques and in numerous other aspects. This literature
review attempts to highlight the key theories and implementation technologies adopted in the design and
development of ITSs during the period under review.
Antigens of Chlamydia trachomatis (1985)

Chlamydia trachomatis is an obligate intracellular parasite that elaborates antigens on its surface. These antigens are divided into genus-, species-, subspecies-, and serovar-specific determinants. The genus, or group antigen(s), are lipopolysaccharides similar to those found in gram-negative bacteria and a glycolipid that is secreted by infected cell cultures. Species-specific antigens differentiate Chlamydia trachomatis from Chlamydia psittaci and are expressed on the outer membrane. These proteins range in molecular weight from 155,000 to approximately 40,000. Monoclonal antibodies to outer-membrane proteins have demonstrated the presence of subspecies-reactive antigenic determinants. Type-specific antigens are associated with the major outer-membrane protein and are secreted from infected cells as well. The molecular weights of these proteins range from 30,000 to 40,000. These antigens may participate in the binding of the organism to target cells and in an enzymatic process of some type that initiates endocytosis. The significance of the soluble antigens detected in the microenvironment in vitro may suggest immune-complex formation, a process that could contribute to the immunopathology of the disease.
Phytochemical Investigation of<i>Turnera</i><i>diffusa</i> (2007)

A phytochemical investigation of Turnera diffusa afforded 35 compounds, comprised of flavonoids, terpenoids, saccharides, phenolics, and cyanogenic derivatives, including five new compounds (1-5) and a new natural product (6). These compounds were characterized as luteolin 8-C-E-propenoic acid (1), luteolin 8-C-beta-[6-deoxy-2-O-(alpha-l-rhamnopyranosyl)-xylo-hexopyranos-3-uloside] (2), apigenin 7-O-(6' '-O-p-Z-coumaroyl-beta-d-glucopyranoside) (3), apigenin 7-O-(4' '-O-p-Z-coumaroylglucoside) (4), syringetin 3-O-[beta-d-glucopyranosyl-(1-->6)-beta-d-glucopyranoside] (5), and laricitin 3-O-[beta-d-glucopyranosyl-(1-->6)-beta-d-glucopyranoside] (6). Their structures were determined by spectroscopic and chemical methods.
Whole-body energy metabolism and metabolic capacity of skeletal muscles in malnourished patients before and after total parenteral nutrition. (1983)

The influence of total parenteral nutrition (TPN) on whole-body energy metabolism and nitrogen balance in relation to the activities of key enzymes, the flux of glucose-carbons, RNA content and protein synthesis in skeletal muscles was evaluated in a study of depleted cancer and non-cancer patients. TPN consisted of D-glucose, lipids and amino acids as 47.8 kJ/g N (200 kcal/gN); 30 per cent of the non-protein energy was glucose and 70 per cent was lipids during 14.9 +/- 1.3 d (mean +/- s.e.). Body weight and body potassium increased during TPN. Positive whole-body energy and nitrogen balance were achieved and associated with improved translational capacity for protein synthesis in skeletal muscle (m. rectus abdominis) in vitro. Increased RNA content of muscle after TPN showed that transcriptional events were involved in vivo. The initial low levels of activities (Vmax) of glycolytic and oxidative key enzymes in skeletal muscle were not significantly changed by the 2-week period of TPN.