gebhart/patrepeval huggingface dataset:
GaAs monolithic implementation of active circulators (2003)

A GaAs monolithic three-transistor signal circulator for 0.2- to 2-GHz applications was developed and tested. The circuit consists of three FETs with gates of 150- mu m width and 0.5- mu m length, three capacitors, and seven GaAs resistors. The resulting chip size is 1.1 mm*1.0 mm on a substrate of thickness 0.15 mm. The ability afforded by monolithic construction techniques to locate the active devices in close proximity to each other and avoid interconnecting circuitry stray capacitance is critical to the high-frequency operation of the device. The three-terminal device demonstrated a 6-dB insertion loss and an 18-dB directivity over the above frequency range.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Review of Progress in Quantitative Nondestructive Evaluation, Volume 19A, AIP Conference Proceedings, No. 509, [APCPCS] (2000)

This volume contains a minisymposium on innovation and nondestructive evaluation (NDE) in a global economy, then proceeds to elastic waves and ultrasonic techniques; electromagnetic, thermal, and x-ray techniques; signal processing, imaging, and inversion techniques; and ultrasonic transducers, fields, and arrays.
Activation by Some T-Independent Antigens and B Cell Mitogens of the Alternative Pathway of the Complement System (1975)

A number of T-independent antigens and B cell mitogens were examined for their ability to activate C3 via the alternative pathway of the complement system. Loss of hemolytically active C3, generation of anaphylatoxin activity, and immunoelectrophoretic conversion of C3 and factor B, were checked in normal and C4-deficient guinea pig serum, and, in some cases, in normal human serum. As judged by their activity in these assays, 10 lipopolysaccharides of different origin and constitution, pneumococcus type III polysaccharide, levan, dinitrophenylated aminoethyl-dextran, dinitrophenylated (D-glutamic acid, D-lysin) copolymer, polymerized flagellin, and pokeweed mitogen were all capable of initiating the alternative pathway, but differed with respect to their potency, their relative activity in the presence or absence of C4, and their ability to inhibit C3-turnover at high concentrations. Polyvinylpyrrolidone of intermediate molecular weight (4 x 10(4) daltons) was only active if the most sensitive assay was used (anaphylatoxin generation). Other species of polyvinylpyrrolidone, depolymerized pneumococcal polysaccharide, aminoethyl-dextran, [D-glutamic acid, D-lysin] copolymer, phytohemagglutinin and concanavalin A failed to activate C3. C3-consumption by concanavalin A was due to nonspecific binding.
Effects of polydispersity in the end-grafted polymer brush (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffects of polydispersity in the end-grafted polymer brushS. T. Milner, T. A. Witten, and M. E. CatesCite this: Macromolecules 1989, 22, 2, 853–861Publication Date (Print):February 1, 1989Publication History Published online1 May 2002Published inissue 1 February 1989https://doi.org/10.1021/ma00192a057RIGHTS & PERMISSIONSArticle Views1490Altmetric-Citations293LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
The effect of conditioning of fused‐silica capillaries on their electrophoretic performance (2007)

In CE practice, conditioning of the capillary tube with strong base, acid, or both in sequence, has been recognized as essential to obtain reasonable precision in electroosmotic mobility (EOM), and consequently, in the migration times of analytes. This report focuses on the comparative study of three different approaches for capillary conditioning: etching with HF, etching with NaOH, and leaching with HCl after NaOH treatment. EOM-based measurements, including the hysteresis effect that characterizes the dependence of EOM with pH, were used to evaluate the conditioned silica surface. Additionally, indirect inspection of the conditioned surface was carried out by examining the electrophoretic profile of the cationic probe Ru(bpy)(3) (2+), known to strongly interact with the ionized silica surface while displaying no significant acid-base activity. It was shown that, once conditioned and prior to any CE measurement, extensive rinse of the capillary with the running electrolyte at high flow rate was essential to attain relatively rapid re-equilibration of the tube with the fluid. Insufficient rinse with the running electrolyte would result in negatively biased EOM measurements and significant drift in migration times. It was also established that relatively high flow rates of 1 M NaOH conditioning solution (4-5 column volumes per minute) was required to attain capillaries with reproducible electrophoretic performance within a reasonable conditioning time (typically, 1 h). In addition to relatively more extensive rehydroxylation of the silica surface, evidenced by the highest EOM values obtained, the sequential use of NaOH-etching and HCl-leaching provided better precision than HF-etching or NaOH-etching alone.
Proposal of Two Subspecies of Fusobacterium necrophorum (Flugge) Moore and Holdeman: Fusobacterium necrophorum subsp. necrophorum subsp. nov., nom. rev. (ex Flugge 1886), and Fusobacterium necrophorum subsp. funduliforme subsp. nov., nom. rev. (ex HallE 1898) (1991)

The biological and biochemical properties, DNA base compositions, and levels of DNA-DNA homology of two biovars of Fusobacterium necrophorum were examined. Some differences were found between the two biovars in biological and biochemical properties. The G + C contents of DNAs from biovar A strains VPI 2891T (T = type strain), NCTC 10576, N167, Fn47, and Fn43, were 32, 30, 29, 28, and 31 mol%, respectively. The G + C contents of DNAs from biovar B strains Fn524T, 606, Fn49, Fn45, and 1260 were 30, 31, 27, 31, and 30 mol%, respectively. Labeled DNA from biovar A strain VPI 2891T exhibited 100 to 80% relatedness to DNAs from biovar A strains and 59 to 51% relatedness to DNAs from biovar B strains. Labeled DNA from biovar B strain Fn524T exhibited 100 to 81% relatedness to DNAs from biovar B strains and 71 to 60% relatedness to DNAs from biovar A strains. Therefore, the names Fusobacterium necrophorum subsp. necrophorum subsp. nov., nom. rev. (ex Flügge 1886), and Fusobacterium necrophorum subsp. funduliforme subsp. nov., nom. rev. (ex Hallé 1898), are proposed for Fusobacterium necrophorum biovars A and B, respectively. The type strain of F. necrophorum subsp. necrophorum is strain VPI 2891 (= JCM 3718 = ATCC 25286), and the type strain of F. necrophorum subsp. funduliforme is strain Fn524 (= JCM 3724).
P2X Receptor–Mediated Ionic Currents in Dorsal Root Ganglion Neurons (1999)

Nociceptive neurons in the dorsal root ganglia (DRG) are activated by extracellular ATP, implicating P2X receptors as potential mediators of painful stimuli. However, the P2X receptor subtype(s) underlying this activity remain in question. Using electrophysiological techniques, the effects of P2X receptor agonists and antagonists were examined on acutely dissociated adult rat lumbar DRG neurons. Putative P2X-expressing nociceptors were identified by labeling neurons with the lectin IB4. These neurons could be grouped into three categories based on response kinetics to extracellularly applied ATP. Some DRG responses (slow DRG) were relatively slowly activating, nondesensitizing, and activated by the ATP analogue alpha,beta-meATP. These responses resembled those recorded from 1321N1 cells expressing recombinant heteromultimeric rat P2X2/3 receptors. Other responses (fast DRG) were rapidly activating and desensitized almost completely during agonist application. These responses had properties similar to those recorded from 1321N1 cells expressing recombinant rat P2X3 receptors. A third group (mixed DRG) activated and desensitized rapidly (P2X3-like), but also had a slow, nondesensitizing component that functionally prolonged the current. Like the fast component, the slow component was activated by both ATP and alpha, beta-meATP and was blocked by the P2X antagonist TNP-ATP. But unlike the fast component, the slow component could follow high-frequency activation by agonist, and its amplitude was potentiated under acidic conditions. These characteristics most closely resemble those of rat P2X2/3 receptors. These data suggest that there are at least two populations of P2X receptors present on adult DRG nociceptive neurons, P2X3 and P2X2/3. These receptors are expressed either separately or together on individual neurons and may play a role in the processing of nociceptive information from the periphery to the spinal cord.
A randomized phase II study of SRL172 (Mycobacterium vaccae) combined with chemotherapy in patients with advanced inoperable non-small-cell lung cancer and mesothelioma (2000)

Mycobacterial preparations have been used with limited success against cancer apart from superficial bladder cancer. Recently, a therapeutic vaccine derived from Mycobacterium vaccae has been given to patients with prostate cancer and melanoma indicating a possible beneficial effect on disease activity in such patients. We have recently initiated a series of randomized studies to test the feasibility and toxicity of combining a preparation of heat-killed Mycobacterium vaccae (designated SRL172) with a multidrug chemotherapy regimen to treat patients with inoperable non-small cell lung cancer (NSCLC) and mesothelioma. 28 evaluable patients with previously untreated symptomatic NSCLC and mesothelioma were randomized to receive either 3 weekly intravenous combination chemotherapy alone, or chemotherapy given with monthly intra-dermal injections of SRL172. Safety and tolerability were scored by common toxicity criteria and efficacy was evaluated by survival of patients and by tumour response assessed by CT scanning. The toxicity of chemotherapy was similar in the two groups. SRL172 caused mild inflammation at the injection site. In the group of patients randomized to receive chemotherapy combined with SRL172, there was a trend towards improved response rate (54% vs. 33%) with more patients in the combined arm receiving radical surgery and radiotherapy, improved median survival (9.7 months vs. 7.5 months) and improved 1 year survival (42% vs. 18%). SRL172 appeared to improve sleep (P = 0.08) and improved appetite (P = 0.01). There was no detectable change in serum cytokine levels for gamma-interferon and TNF-α before and after treatment. In patients with NSCLC and mesothelioma, there may be a beneficial interaction when chemotherapy is administered in combination with SRL172. Confirmation of this effect and further investigation is underway in a randomized phase III trial and in laboratory models. © 2000 Cancer Research Campaign
Cholesterol Metabolites 25-Hydroxycholesterol and 25-Hydroxycholesterol 3-Sulfate Are Potent Paired Regulators: From Discovery to Clinical Usage (2020)

Oxysterols have long been believed to be ligands of nuclear receptors such as liver × receptor (LXR), and they play an important role in lipid homeostasis and in the immune system, where they are involved in both transcriptional and posttranscriptional mechanisms. However, they are increasingly associated with a wide variety of other, sometimes surprising, cell functions. Oxysterols have also been implicated in several diseases such as metabolic syndrome. Oxysterols can be sulfated, and the sulfated oxysterols act in different directions: they decrease lipid biosynthesis, suppress inflammatory responses, and promote cell survival. Our recent reports have shown that oxysterol and oxysterol sulfates are paired epigenetic regulators, agonists, and antagonists of DNA methyltransferases, indicating that their function of global regulation is through epigenetic modification. In this review, we explore our latest research of 25-hydroxycholesterol and 25-hydroxycholesterol 3-sulfate in a novel regulatory mechanism and evaluate the current evidence for these roles.
Design of anisotropic focusing metasurface and its application for high-gain lens antenna (2016)

In this paper, we propose an anisotropic focusing metasurface with function of focusing orthogonally polarized waves in refraction and reflection modes respectively. By employing four layered metallic patches spaced by triple layered dielectric spacers, an anisotropic phase element is designed with capability of transmitting x-polarized waves but reflecting y-polarized beams efficiently. Composed of 21 21 cells and with size of 105 105 mm2, a focusing metasurface operating at 15 GHz is designed with the same focal length of 30 mm for x- and y-polarized waves. By setting a patch antenna at the focal point, the metasurface sample is employed to enhance gain of the radiation source. For verification, the metasurface sample is fabricated and measured. The antenna performance, in terms of realized boresight gain and operating bandwidth under x- and y-polarized waves illumination, is presented. Results show that the 1 dB gain bandwidths are respectively from 14.7 to 15.3 GHz and 14.7 to 15.2 GHz, and the gain are enhanced by 14.1 dB, 15.1 dB in refraction and reflection modes when the metasurface is impinged by x- and y-polarized spherical waves. The proposed anisotropic metasurface may afford an alternative for designing anisotropic planar lens or high-gain antenna.
A testable CMOS signal processor for fast Fourier transforms (2003)

The authors present the architecture of a fast Fourier transform processor which has high performance characteristics and an embedded test structure that allows the processor to test itself during normal operation. The properties of separable residue codes have been used for error detection in the arithmetic unit of the processor. Offline error detection which tests for the classic stuck at faults is based on the properties of the dynamic CMOS logic design used. The testing circuitry used in the architecture accounts for only a 20% area overhead and no time ahead, an important saving in a signal-processing environment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
An Information Theoretic Approach to Content Based Image Retrieval. (2000)

We propose an information theoretic approach to the representation and comparison of color features in digital images to handle various problems in the area of content-based image retrieval. The interpretation of color histograms as joint probability density functions enables the use of a wide range of concepts from information theory to be considered in the extraction of color features from images and the computation of similarity between pairs of images. The entropy of an image is a measure of the randomness of the color distribution in an image. Rather than replacing color histograms as an image representation, we demonstrate that image entropy can be used to augment color histograms for more efficient image retrieval. We propose an indexing algorithm in which image entropy is used to drastically reduce the search space for color histogram computations. Our experimental tests applied to an image database with 10,000 images suggest that the image entropy-based indexing algorithm is scalable for image retrieval of large image databases. We also proposed a new similarity measure called the maximum relative entropy measure for comparing image feature vectors that represent probability density functions. This measure is an improvement of the Kullback-Leibler number in that it is non-negative and satisfies the identity and symmetry axioms. We also propose a new usability paradigm called Query By Example Sets (QBES) that allows users, particularly novice users, the ability to express queries in terms of multiple images.
A multi layer meander line circular polarization selective structure (MLML-CPSS) (2014)

A circular polarization selective structure (CPSS) reflects one handedness of circular polarization and transmits the other. We present a new multilayer structure with significantly improved bandwidth compared to classical solutions, which are typically based on resonant structures. The proposed structure consists of layers of printed metal meander lines interspaced by low-permittivity rigid foams. Simulation results for a five layer design are given, demonstrating return loss and insertion loss less than 0.5 dB and axial ratio less than 0.75dB over the entire Ku-band (12-18 GHz, 40% fractional bandwidth), for 0-20 degrees angle of incidence.
Error performance of maximal-ratio combining with transmit antenna selection in flat Nakagami-m fading channels (2009)

In this paper, the performance of an uncoded multiple-input-multiple-output (MIMO) scheme combining single transmit antenna selection and receiver maximal-ratio combining (the TAS/MRC scheme) is investigated for independent flat Nakagami-m fading channels with arbitrary real-valued m. The outage probability is first derived. Then the error rate expressions are attained from two different approaches. First, based on the observation of the instantaneous channel gain, the binary phase-shift keying (BPSK) asymptotic bit error rate (BER) expression is derived, and the exact BER expression is obtained as an infinite series, which converges for reasonably large signal-to-noise ratios (SNRs). Then the exact symbol error rate (SER) expressions are attained as a multiple infinite sum based on the moment generating function (MGF) method for M-ary phase-shift keying (M-PSK) and quadrature amplitude modulation (M-QAM). The asymptotic SER expressions reveal a diversity order equal to the product of the m parameter, the number of transmit antennas and the number of receive antennas. Theoretical analysis is verified by simulation.
Bipartite Modular Structure of Intrinsic, RNA Hairpin-independent Termination Signal for Phage RNA Polymerases (1999)

The phage SP6 RNA and T7 RNA polymerases, which are closely related to each other, intrinsically stop at two signals in the Escherichia coli rrnB terminator t1 through different mechanisms. The downstream signal functioned without an RNA secondary structure formation, in which the signal was still active when separated from the upstream, hairpin-forming signal, and IMP incorporation enhanced its efficiency. The sequence from -15 to -1 was essential for the downstream, hairpin-independent termination (at -1). The results of SP6 transcription with heteroduplex templates and ribonucleotide analogs suggested that the downstream signal consists of two functionally different modules. The effects of iodo-CMP or IMP incorporation into RNA on termination efficiency were not sensitive to incorporation at -9 and upstream, but they were reactive to incorporation at -6 and -2, as reflected by strong iodo-rC:dG and weak rI:dC base pairing. Thus, the downstream module (from -8 approximately -6 to -1) appears to facilitate the release of RNA. Mismatches in the templates at -6 to +1 allowed for efficient termination, unlike those upstream of the sequence. The upstream module (from -15 to -9 approximately -7) functions as a duplex. Pausing of the SP6 elongation complex at the termination site was detected when RNA release was suppressed by the incorporation of 5-bromo-UMP, and it was dependent on the upstream module. Results of single-round SP6 transcriptions using 3'-deoxynucleotides and immobilized templates indicated that RNA was not released from the elongation complexes halted at the termination site on the template variants carrying mutations in the upstream or downstream module, whereas such complexes on the wild type template were dissociated. Thus, halting or simple pausing was not sufficient for termination even when the downstream module was intact. The upstream module appears to mediate such conformation change necessary for termination.
Carrier Modulation Layer-Enhanced Organic Light-Emitting Diodes (2015)

Organic light-emitting diode (OLED)-based display products have already emerged in the market and their efficiencies and lifetimes are sound at the comparatively low required luminance. To realize OLED for lighting application sooner, higher light quality and better power efficiency at elevated luminance are still demanded. This review reveals the advantages of incorporating a nano-scale carrier modulation layer (CML), also known as a spacer, carrier-regulating layer, or interlayer, among other terms, to tune the chromaticity and color temperature as well as to markedly improve the device efficiency and color rendering index (CRI) for numerous OLED devices. The functions of the CML can be enhanced as multiple layers and blend structures are employed. At proper thickness, the employment of CML enables the device to balance the distribution of carriers in the two emissive zones and achieve high device efficiencies and long operational lifetime while maintaining very high CRI. Moreover, we have also reviewed the effect of using CML on the most significant characteristics of OLEDs, namely: efficiency, luminance, life-time, CRI, SRI, chromaticity, and the color temperature, and see how the thickness tuning and selection of proper CML are crucial to effectively control the OLED device performance.
Protease stabilization by carboxylic acid salts: Relative efficiencies and mechanisms (1989)

Abstracts Kinetic studies are presented on the inhibition of proteolysis by carboxylic acid salts on the synthetic substrate succinyl ala‐ala‐pro‐phe‐para nitroanilide. The inhibition of proteolysis/autodigestion is shown to be the major factor in the stabilization of a detergent protease [i.e., Maxatase (subtilisin Carlsberg)] in an unbuilt, liquid, heavy duty laundry formulation. The inhibition of autodigestion by a carboxylic acid salt as a function of pH parallels the protease stability increase during accelerated aging. Relative inhibition of proteolysis and protease stabilization by various carboxylic acid salts are compared.
Modelling and Verification of Real-Time Systems Using Timed Automata : Theory and Practice (1999)

During the last decade, model-checking techniques for the verification of timed system have been developed baaed on the theory of timed automata. The practical limitation in applying these techniqu ...