gebhart/patrepeval huggingface dataset:
Designing and Evaluating Home-Based, Just-in-Time Supportive Technology. (2005)

At MIT, a multi-disciplinary team of researchers is studying how to create pervasive computing environments for the home. We are developing technologies and design strategies that use context-aware sensing to empower people with information by presenting it at precisely the right time and place. Contrary to many visions of future home environments in the literature, we advocate an approach that uses technology to teach as opposed to using technology primarily for automated control. We have constructed a "living laboratory" that will provide a unique, flexible infrastructure for scientifically studying the power of pervasive computing for motivating learning and behavior change in the home. This facility, called the PlaceLab, is being used to study technology for creating homes that are supportive.
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein (1997)

Six Escherichia coli and 12 Klebsiella pneumoniae isolates from a single hospital expressed a common beta-lactamase with a pI of approximately 9.0 and were resistant to cefoxitin and cefotetan (MIC ranges, 64 to > 128 and 16 to > 128 micrograms/ml, respectively). Seventeen of the 18 strains produced multiple beta-lactamases. Most significantly, three K. pneumoniae strains were also resistant to imipenem (MICs, 8 to 32 micrograms/ml). Spectrophotometric beta-lactamase assays with purified enzyme indicated hydrolysis of cephamycins, in addition to cephaloridine and benzylpenicillin. The 4ene encoding the pI 9.0 beta-lactamase (designated ACT-1 for AmpC type) was cloned and sequenced, which revealed an ampC-type beta-lactamase gene that originated from Enterobacter cloacae and that had 86% sequence homology to the P99 beta-lactamase and 94% homology to the partial sequence of MIR-1. Southern blotting revealed that the gene encoding ACT-1 was on a large plasmid in some of the K. pneumoniae strains as well as on the chromosomes of all of the strains, suggesting that the gene is located on an easily mobilized element. Outer membrane protein profiles of the K. pneumoniae strains revealed that the three imipenem-resistant strains were lacking a major outer membrane protein of approximately 42 kDa which was present in the imipenem-susceptible strains. ACT-1 is the first plasmid-mediated AmpC-type beta-lactamase derived from Enterobacter which has been completely sequenced. This work demonstrates that in addition to resistance to cephamycins, imipenem resistance can occur in K. pneumoniae when a high level of the ACT-1 beta-lactamase is produced in combination with the loss of a major outer membrane protein.
Managing Disruptive and Compulsive Behaviors in Adult With Autistic Disorder With Gabapentin (2013)

Guglielmo, Riccardo MD; Ioime, Lucia Psy-D; Grandinetti, Paolo MD; Janiri, Luigi MD Author Information
Learning based on conceptual distance (1988)

An approach to concept learning from examples and concept learning by observation is presented that is based on a intuitive notion of conceptual distance between examples (concepts) and combines symbolical and numerical methods. The approach is based on the observation that very different examples generalize to an expression that is very far from each of them, while identical examples generalize to themselves. Following this idea the authors propose some domain-independent and intuitively justified estimates for the conceptual distance. A hierarchical conceptual clustering algorithm that groups objects so as to maximize the cohesiveness (a reciprocal of the conceptual distance) of the clusters is presented. It is shown that conceptual clustering can improve learning from complex examples describing objects and the relation between them.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
SCV2: A model-based validation and verification approach to system-of-systems engineering (2015)

Model-Based Systems Engineering provides an effective methodology for designing complex systems and System-of-Systems. More importantly, such an approach opens the possibility to automatically generate executable simulators from system modules using model-to-code transformations, in order to verify the system model's completeness and validate design requirements. However, the user may still need to write code segments to describe the detailed functionality of system components. In this paper, we present the SCV <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> tool, which allows the simulation of big size heterogeneous/multiple-class systems and system-of-systems, imposes code-model consistency and aided statechart design through reverse code-to-model transformations, and provides query-based requirement validation and functionality verification through an intuitive user interface. Finally, we present a use-case showing the utilization of the tool in the WiBRATE FP7 project for early-stage validation of system requirements.
Digital dual-rate burst-mode receiver for 10G and 1G coexistence in optical access networks (2011)

A digital dual-rate burst-mode receiver, intended to support 10 and 1 Gb/s coexistence in optical access networks, is proposed and experimentally characterized. The receiver employs a standard DC-coupled photoreceiver followed by a 20 GS/s digitizer and the detection of the packet presence and line-rate is implemented in the digital domain. A polyphase, 2 samples-per-bit digital signal processing algorithm is then used for efficient clock and data recovery of the 10/1.25 Gb/s packets. The receiver performance is characterized in terms of sensitivity and dynamic range under burst-mode operation for 10/1.25 Gb/s intensity modulated data in terms of both the packet error rate (PER) and the payload bit error rate (pBER). The impact of packet preamble lengths of 16, 32, 48, and 64 bits, at 10 Gb/s, on the receiver performance is investigated. We show that there is a trade-off between pBER and PER that is limited by electrical noise and digitizer clipping at low and high received powers, respectively, and that a 16/2-bit preamble at 10/1.25 Gb/s is sufficient to reliably detect packets at both line-rates over a burst-to-burst dynamic range of 14,5 dB with a sensitivity of -18.5 dBm at 10 Gb/s.
Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H<sub>1</sub>‐receptor antagonist with negligible ability to penetrate the central nervous system (1986)

SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist, has been studied in a variety of in vitro and in vivo test systems. SK&F 93944 was a competitive antagonist of histamine-induced contractions of guinea-pig ileum with a pA2 of 9.55 and a weak, non-competitive, inhibitor of the effects of histamine on guinea-pig atrium. In anaesthetized guinea-pigs SK&F 93944 displaced histamine bronchoconstriction dose-response curves at doses which had negligible effects on histamine tachycardia. In anaesthetized cats SK&F 93944 antagonized depressor responses to the histamine H1-receptor agonists, 2-(2-aminoethyl)pyridine and betahistine, at doses which had no effects on responses to the histamine H2-receptor agonist, dimaprit. Oral pretreatment with SK&F 93944 in conscious rats and guinea-pigs afforded protection versus the response to intradermal histamine injection. Comparative studies in each of the test systems showed that SK&F 93944 was of comparable or significantly greater potency than the standard compound, mepyramine. SK&F 93944 was found to be a weak, non-competitive antagonist of carbachol on the guinea-pig ileum but was devoid of measurable anticholinergic activity in vivo. Studies on the penetration of [14C]-SK&F 93944, labelled either in the isocytosine ring or in the butyl chain, showed that brain concentrations were very low when compared with the steady-state blood concentrations. In contrast, brain concentrations of [3H]-mepyramine exceeded blood concentrations by a factor of approximately 3. SK&F 93944 may have an advantage over classical histamine H1-receptor antagonists in that it is likely to be devoid of untoward effects on the central nervous system.
Poly-β-L-aspartic Acid. Synthesis through Pentachlorophenyl Active Ester and Conformational Studies (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPoly-β-L-aspartic Acid. Synthesis through Pentachlorophenyl Active Ester and Conformational StudiesJ. Kovacs, R. Ballina, R. L. Rodin, D. Balasubramanian, and Jon ApplequistCite this: J. Am. Chem. Soc. 1965, 87, 1, 119–120Publication Date (Print):January 1, 1965Publication History Published online1 May 2002Published inissue 1 January 1965https://pubs.acs.org/doi/10.1021/ja01079a022https://doi.org/10.1021/ja01079a022research-articleACS PublicationsRequest reuse permissionsArticle Views301Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Bayesian approaches to Gaussian mixture modeling (1998)

A Bayesian-based methodology is presented which automatically penalizes overcomplex models being fitted to unknown data. We show that, with a Gaussian mixture model, the approach is able to select an "optimal" number of components in the model and so partition data sets. The performance of the Bayesian method is compared to other methods of optimal model selection and found to give good results. The methods are tested on synthetic and real data sets.
<i>In vivo</i>and<i>in situ</i>detection of colorectal cancer using Fourier transform infrared spectroscopy (2005)

FTIR fiber-optic attenuated total reflectance (ATR) spectroscopy can identify in situ and in vivo colorectal cancer. FTIR spectroscopic method with fiber optics is a non-invasive, rapid, accurate and in vivo cancer detection technique in clinical diagnosis.
Stress reduction in ion beam sputtered mixed oxide films (1989)

Thin films deposited by ion beam sputtering typically have a high compressive stress. This paper demonstrates that this stress can be reduced by cosputtering two materials. Thin film mixtures of zirconia (ZrO(2)) and silica (SiO(2)) were prepared with a range of compositions using ion beam sputtering. The refractive index was found to vary almost linearly with composition. The large stress observed in zirconia films was found to be reduced significantly by the addition of silica.
A Study of Industrial Workers' Knowledge, Attitude, and Practice of Health Care Services in Busan City (1993)

【The purpose of this study was to identify the workers the Knowledge, Attitude, and Practice of industrial health care services. The study was conducted from Dec 10, 1992 to Jan 20, 1993. The data was collected from 849 workers in 56 companies in Busan City. The data was analyzed by using the mean, S.D>, T-test, ANOVA. The tool for measuring the degree of Knowledge, Attitude and Practice of industrial health care of workers was developed by community health nursing academy and the reliability an of the tool was 0.82810. The results were as follows : 1. The general characteristics of workers : Distribution of workers consisted of laborer(55.0%), office workers(45.0%), in an age range from 25-39(55.0%), male employees were(69.7%), married employees were(62.4%), the educational level with the highest percentage was high school graduates(54.2%). The present work force had a career for 7 years or more with an income of 300-700 thousand won monthly(43.2). 2. The degree of Knowledge Attitude and Practice about industrial health care services of workers : The total score of the Knowledge, Attitude, and Practice was 49.09 points out of a possible 80(mean Score=2.46) 1) The total score of the Knowledge was 15.73 points out of 24. (Mean score=2.62) The following are the Knowledge scores: The necessity examination of occupational disease was(3.34) The knowledge of occupational disease was (3.12) The knowledge of health education was(1.29) 2) b. The total score of the Attitude was 26.01 point out of 44(mean score=2.36) The following are the Attitude scores: The necessity of health education for health examination was (3.14). The importance of health examination was(3.08) The necessity of measurement for working environment was(2.99). The satisfaction of the content in the periodic health examination was low(1.81). 3) The total score of the Practice was 7.35 points out of 12(mean score=2.45) The following are the orders of Practice scores: The participation in health examination was higher than in health education(1.33). 3. The general characteristics and the degree of knowledge, Attitude, and Practice of workers of industrial health care. 1) The level of worker's knowledge was significantly related by working part(t=2.54 P=0.000), marital status(F=4.35 P=0.029), educational level(F=3.91 and P=0.020), monthly income(F=2.98 P=0.029) 2) There were no significant difference between the general characteristics and the attitude of workers. 3) The practice was significantly related with working part(T=2.52 P=0.012), sex(T=2.28 P=0.23), marital status(F=4.25 P=0.012), monthly income (F=2.76 P=0.034) 4) The total score had a significant difference with working part(T=2.39 P=0.017), sex (T=3.84 P=0.000), marital status (F=3.18 P=0.032). Educational level (F=3.20 P=0.033), and monthly income(F=3.05 P=0.022).】
Matrix metalloproteinases in diabetic retinopathy: potential role of MMP-9 (2012)

Inhibitors of MMPs could have dual role: in the early stages of the diseases, inhibit capillary cell apoptosis, and if the disease has progressed to the angiogenic stage, inhibit the growth of new vessels.
Expression analysis of a GA 20‐oxidase in embryos from two sorghum lines with contrasting dormancy: possible participation of this gene in the hormonal control of germination (2003)

The role of GAs in promoting seed germination is well known and experiments with seeds from different species have suggested the requirement of de novo synthesis of GAs upon imbibition for germination. There are also strong indications that the enhancement of GA synthesis is part of the mechanism through which environmental signals (i.e. light) induce germination. Since along the GA biosynthetic pathway, oxidation at C-20 carried out by GA 20-oxidases is thought to be a site of regulation, a cDNA clone encoding a GA 20-oxidase was isolated from embryos of sorghum (SbGA 20ox). Expression analysis of this gene in embryos within imbibed caryopses with low dormancy showed detectable amounts of the specific mRNA early upon incubation, increasing thereafter. In contrast, it remained barely detectable in embryos from dormant caryopses. Changes in endogenous GA4 levels were in agreement with those of SbGA 20ox mRNA, suggesting that GA production might be regulated differentially at the level of transcription of this gene. The expression of SbGA 20ox was enhanced in incubated embryos isolated from either type of caryopses, illustrating a physiological control exerted by the surrounding seed tissues on gene expression. The results also show that ABA leads to a suppression of transcription of this gene.
Fitting behaviors to pedestrian simulations (2009)

In this paper we present a data-driven approach for fitting behaviors to simulated pedestrian crowds. Our method annotates agent trajectories, generated by any crowd simulator, with action-tags. The aggregate effect of animating the agents according to the tagged trajectories enhances the impression that the agents are interacting with one another and with the environment. In a preprocessing stage, the stimuli which motivated a person to perform an action, as observed in a crowd video, are encoded into examples. Using the examples, non-linear, action specific influence functions are encoded into two-dimensional maps which evaluate, for each action, the relative importance of a stimulus within a configuration. At run time, given an agents stimuli configuration, the importance of each stimulus is determined and compared to the examples. Thus, the probability of performing each action is approximated and an action-tag is chosen accordingly. We fit behaviors to pedestrian crowds, thereby enhancing their natural appearance.
Effect of Fasudil Hydrochloride, a Protein Kinase Inhibitor, on Cerebral Vasospasm and Delayed Cerebral Ischemic Symptoms After Aneurysmal Subarachnoid Hemorrhage-Results of a Randomized Trial of Fasudil Hydrochloride Versus Nimodipine- (2006)

The efficacy and safety of fasudil hydrochloride, a novel protein kinase inhibitor, were evaluated for the treatment of cerebral vasospasm and associated cerebral ischemic symptoms in patients with ruptured cerebral aneurysm. This randomized open trial with nimodipine as the control included 72 patients who underwent subarachnoid hemorrhage surgery for ruptured cerebral aneurysm of Hunt and Hess grades I to IV. For 14 days following surgery, patients were administered either 30 mg of fasudil hydrochloride by intravenous injection over a period of 30 minutes three times a day or 1 mg/hr of nimodipine by continuous intravenous infusion. Fasudil hydrochloride and nimodipine both showed inhibitory effects on cerebral vasospasm. The incidence of symptomatic vasospasm was five of 33 patients in the fasudil group and nine of 32 patients in the nimodipine group. Good recovery evaluated by the Glasgow Outcome Scale was achieved by 23 of 33 patients in the fasudil group and 19 of 34 patients in the nimodipine group. Both drugs significantly improved consciousness levels and neurological deficits such as aphasia. However, fasudil hydrochloride improved motor disturbance more than nimodipine. Adverse reactions occurred in 13 of 37 patients receiving fasudil hydrochloride and 15 of 35 patients receiving nimodipine. There were no serious adverse events in the fasudil group. The results of this clinical trial indicate that fasudil hydrochloride is a safe and efficient agent for suppressing cerebral vasospasm after subarachnoid hemorrhage surgery for ruptured cerebral aneurysm.
1.54 mu nm Er/sup 3+/-doped fibre amplifier optically pumped at 807 nm (1988)

The authors report the demonstration of an 8 dB single pass fibre amplifier. The operating wavelength was around 1540 nm and a gain bandwidth product of 9 THz was measured. The pump wavelength was 807 nm and the pump power levels required were within the capability of commercially available semiconductor-laser sources. Bit error rate measurements were carried out for a data rate of 140 mb/s.
AN ANALYSIS OF APPLYING S-BAND SAR OF HJ-1C TO SOIL MOISTURE CHANGE RETRIEVAL (2009)

An algorithm for soil moisture change estimation is proposed by using S-band (3.0GHz) and VV polarization simulated backscattering-data based on IEM model. Such typical parameters as soil moisture, surface roughness and incidence angle are chosen to simulate two radar images for validation and improvement of the algorithm. The comparison results are well consistent with the inputting parameters under the applicable condition, which shows that the method can estimate spatial and temporal change of soil moisture.
The general utility of a neuroprosthetic device under direct cortical control (2004)

We have described an adaptive signal processing method that allows fine graded control of a cursor in three-dimensions from cortical signals. Here we describe application of the same signal processing method to direct cortical control of a robotic arm for a variety of tasks. Our subject was extensively trained in controlling a computer cursor in a 3D virtual environment. We applied the mapping between cortical activity and cursor motion to endpoint control of a robotic arm. This algorithm was refined further as the animal continued to make 3D point-to-point movements of the brain-controlled robot. The animal then used the cortically-controlled robot to retrieve food placed at arbitrary locations within the workspace and deliver the food to a hopper. Finally, the animal learned to use the cortically-controlled robot to deliver food directly to its mouth.
Query-Based Abstractive Summarization Using Neural Networks (2017)

In this paper, we present a model for generating summaries of text documents with respect to a query. This is known as query-based summarization. We adapt an existing dataset of news article summaries for the task and train a pointer-generator model using this dataset. The generated summaries are evaluated by measuring similarity to reference summaries. Our results show that a neural network summarization model, similar to existing neural network models for abstractive summarization, can be constructed to make use of queries to produce targeted summaries.