gebhart/patrepeval huggingface dataset:
Cardiology and internal medicine (1998)

Presented by Nova Southeastern University; hosted by Fred Lippman, Executive Vice Chancellor Health Professions Division; with guest A. Alvin Greber, D.O.
The trilateral filter for high contrast images and meshes (2005)

We present a new, single-pass nonlinear filter for edge-preserving smoothing and visual detail removal for N dimensional signals in computer graphics, image processing and computer vision applications. Built from two modified forms of Tomasi and Manduchi's bilateral filter, the new "trilateral" filter smoothes signals towards a sharply-bounded, piecewise-linear approximation. Unlike bilateral filters or anisotropic diffusion methods that smooth towards piecewise constant solutions, the trilateral filter provides stronger noise reduction and better outlier rejection in high-gradient regions, and it mimics the edge-limited smoothing behavior of shock-forming PDEs by region finding with a fast min-max stack. Yet the trilateral filter requires only one user-set parameter, filters an input signal in a single pass, and does not use an iterative solver as required by most PDE methods. Like the bilateral filter, the trilateral filter easily extends to N-dimensional signals, yet it also offers better performance for many visual applications including appearance-preserving contrast reduction problems for digital photography and denoising polygonal meshes.
Laser-driven nuclear-polarized hydrogen internal gas target (2006)

We report the performance of a laser-driven polarized internal hydrogen gas target (LDT) in a configuration similar to that used in scattering experiments. This target used the technique of spin-exchange optical pumping to produce nuclear spin polarized hydrogen gas that was fed into a cylindrical storage (target) cell. We present in this paper the performance of the target, methods that were tried to improve the figure-of-merit (FOM) of the target, and a Monte Carlo simulation of spin-exchange optical pumping. The dimensions of the apparatus were optimized using the simulation and the experimental results were in good agreement with the results from the simulation. The best experimental result achieved was at a hydrogen flow rate of $1.1\ifmmode\times\else\texttimes\fi{}{10}^{18}\phantom{\rule{0.3em}{0ex}}\text{atoms}∕\mathrm{s}$, where the sample beam exiting the storage cell had 58.2% degree of dissociation and 50.5% polarization. Based on this measurement, the atomic fraction in the storage cell was 49.6% and the density averaged nuclear polarization was 25.0%. This represents the highest FOM for hydrogen from an LDT and is higher than the best FOM reported by atomic beam sources that used storage cells.
Animal models of peritonitis. (1976)

A reproducible animal model of peritonitis has been developed. It uses standard animals, standardized cultures of bacteria and simple techniques. Use of this model would facilitate comparison of data from workers in this field. The use of small rodents permits the use of comparatively large populations for statistical evaluation. The method is cheap and economic of laboratory space and does not require surgical expertise.
Model based vision as feedback for virtual reality robotics environments (2002)

Task definition methods for robotic systems are often difficult to use. The "on-line" programming methods are often time expensive or risky for the human operator or the robot itself. On the other hand, "off-line" techniques are tedious and complex. In addition operator training is costly and time consuming. In a Virtual Reality Robotics Environment (VRRE), users are not asked to write down complicated functions, but can operate complex robotic systems in an intuitive and cost-effective way. However a VRRE is only effective if all the environment changes and object movements are fed-back to the virtual manipulating system. The paper describes the use of a VRRE for a semi-autonomous robot system comprising an industrial 5-axis robot, its virtual equivalent and a model based vision system used as feed-back. The user is immersed in a 3-D space built out of models of the robot's environment. He directly interacts with the virtual "components", defining tasks and dynamically optimizing them. A model based vision system locates objects in the real workspace to update the VRRE through a bi-directional communication link. In order to enhance the capabilities of the VRRE, a reflex-type behavior based on vision has been implemented. By locally (independently of the VRRE) controlling the real robot, the operator is discharged of small environmental changes due to transmission delays. Thus once the tasks have been optimized on the VRRE, they are sent to the real robot and a semi autonomous process ensures their correct execution thanks to a camera directly mounted on the robot's end effector. On the other hand if the environmental changes are too important, the robot stops, re-actualizes the VRRE with the new environmental configuration, and waits for task redesign. Because the operator interacts with the robotic system at a task oriented high level, VRRE systems are easily portable to other robotics environments (mobile robotics and micro assembly).
Rapid quantification of viable bacteria in water using an ATP assay (2001)

nformation on the total number of bacteria in water has played a key role in assessing changes during water treatment. Based on the results of bacteriological tests, water treatment works can optimize treatment processes. If the treatment process is not adjusted in time, there may be insufficient treatment or breakthough, resulting in contamination of the entire water distribution system. Thus, rapid determination of the total bacterial count in drinking water is critical to the operators of treatment plants and distribution systems since it allows corrective measures to be taken immediately. Such measures include increasing the disinfectant dose or flushing and disposing of water with high bacterial counts. Operators can also detect whether a water supply system has been intentionally contaminated with biological agents if bacterial count is determined. Heterotrophic plate count (HPC) is a procedure used to estimate the number of heterotrophic bacteria that form colonies on agar plates. The HPC analysis presently employed takes seven days and is not amenable to operator intervention. Techniques available to rapidly detect bacteria include fluorescence microscopic methods, detection of specific metabolites, antibody methods, and DNA-based methods. 1 However, many of these methods are expensive; require an enrichment step, sophisticated equipment, and expertise; are not able to determine viability; and are not suitable for routine analysis. The determination of adenosine triphosphate ( ATP) with a bioluminescence assay may solve the problems encountered in the detection of viable bacteria. The main function of the assay is to quantitate AT P, the important compound in metabolism that is found within all living cells. The assay is based on the reaction between the luciferase (enzyme), luciferin (substrate), and AT P. Light is emitted during the react i o n , 2 and can be measured quantitatively and correlated with the ATP quantity extracted from bacteria. This applications note describes the ability of the ATP assay to determine the total bacterial count in water in minutes with a handheld luminometer. For quality control purposes and to test the accuracy of the AT P and HPC tests, enumeration of the bacteria in a water sample was done using two epifluorescence microscopic methods: acridine orange direct count (AODC) and direct viable count (DVC). Water samples came from local, national, and international locations, which were selected based on their proximity to the l a b o r a t o ry, cooperating water utilities, and the authors. The ATP assay was also used to determine whether the method is applicable for ascertaining the bacterial levels in swimming pools and whirlpools. Decisions regarding the closing and reopening of a pool can be made promptly because bacteriological data are obtained in minutes. Pool safety can be increased since disinfectants can be added in a timely manner.
Real-Time Performance Modeling for Adaptive Software Systems (2009)

Modern, adaptive software systems must often adjust or reconfigure their architecture in order to respond to continuous changes in their execution environment. Efficient autonomic control in such systems is highly dependent on the accuracy of their representative performance model. In this paper, we
Obesity as a risk factor for osteoarthritis: mechanical versus metabolic. (2004)

Obesity is a risk factor for the development and progression of radiograhic OA and probably works through both mechanical as well as metabolic pathways. We are just beginning to unravel these associations. By better understanding these associations, improved biomarkers for development and progression of OA and new novel therapies for the prevention and treatment of OA may be developed. The Osteoarthritis Initiative will help us understand these associations and allow us to evaluate new biomarkers for symptomatic incident and progression of established knee OA as well as the relationship of obesity and generalized OA.
Distributed admission control via dual-queue management (2003)

This paper introduces and studies a new queue management framework via the use of connection level information already embedded in existing data traffic. Our goal is to improve the system performance and resource utilization at times of intense network congestion. Under this framework, data packets and connection establishment packets are queued separately. Different queueing and dropping policies can then be applied to them, thus the term dual-queue management. This framework is stateless and does not require per-flow queueing or flow counting. Using examples of such policies our initial simulation shows that this scheme can lead to much higher performance and network resource utilization during severe congestion. It also leads to more robust and scalable network design. Moreover, it provides an attractive mechanism for network provisioning via parameter tuning.
Numerical Investigation of Single-mode Operation Flat Fiber and Dispersion (2016)

A Single-mode flat fiber investigated by mode matching filtering technique is presented. This class of rectangular optical fiber employed a mode filtering technique to filter high order modes. Fresnel leakage loss induced the propagation modal loss favors fundamental mode, whereas significantly filtered higher-order mode due to modal loss. This resulting mode operation can be expanded via high-aspect-ratio. We numerically analyze the via full-vectorical numerical analysis. We also cover the dispersion analysis to be estimated around wavelength of 1268 nm.
Feasibility of Capacitive Sensing of Surface Electromyographic Potential through Cloth (2012)

A capacitive sensing method was developed for sensing surface electromyographic potential (sEMG) through a thin cloth. The method is based on capacitive coupling involving fabric electrodes, the cloth, and the skin of the subject. A proposed measuring device was assembled by modifying the previously developed instrument for electrocardiographic potential. Experimental results showed that sEMG obtained with the proposed system was clearly visible and showed firings synchronized with sEMG simultaneously measured with a commercial device and that the spectral powers of both sEMGs were almost identical. These results demonstrated the potential of the proposed method to measure sEMG through cloth. The method enables the discomfort due to conventional skin-to-electrode coupling to be eliminated, although the signal quality, such as the signal-to-noise ratio (S/N), is slightly decreased with the cloth barrier.
Functional Vasopressin V1 Type Receptors are Present in Variant as Well as Classical Forms of Small-Cell Carcinoma (1997)

Vasopressin and other neuropeptides are believed to serve as autocrine growth factors for small-cell carcinoma of the lung (SCCL), and these mitogenic influences are reported to involve increases in intracellular Ca2+. Of the classical and variant forms of SCCL, the latter is not only more drug-resistant but also refractory to vasopressin, and other peptides, with respect to changes in intracellular Ca2+. It is currently unclear if this refractiveness of variant SCCL is due to the absence of involved peptide receptors, to the production of abnormal receptors, or to abnormalities in components of induced transduction cascades. In this study, the presence of structurally-normal and functional vasopressin V1a receptors, was examined in a classical SCCL cell line (NCI H345) that is Ca(2+)-responsive to vasopressin, and a variant SCCL cell line (NCI H82) that is unresponsive in this regard to the peptide. Both cell lines were shown to express an mRNA of 1.9 Kb for the vasopressin V1a receptor. RT-PCR, cloning, and DNA sequencing revealed the structure of the mRNA was identical for both cell lines, and, in turn, identical to the mRNA expressed for this receptor by human liver cells. In both cell lines and liver, this mRNA was shown by Western analysis and RIA to generate major protein products of approximately 70,000 and 43,000 daltons. Vasopressin action on NCI H82 cells resulted in a substantial rise in the levels of total inositol phosphates. However, it was reaffirmed that these changes in inositol phosphates were not accompanied by a rise in Ca2+ levels. All of these data indicate that variant SCCL, as well as classical SCCL, expresses structurally-normal and functional vasopressin V1a receptors, but their activation in variant SCCL raises IP3 levels without a corresponding rise in intracellular Ca2+. This difference between the two SCCL sub-types therefore involves either steps in the inositol triphosphate cascade beyond the activation of phospholipase C, or alternatively, components of other transduction events that might be involved with changes in intracellular Ca2+.
An Evaluation of Minocycline in Patients With Periodontal Disease (1980)

The purpose of this study was to determine the passage into and concentration of Minocycline HCl (Minocin) in gingival crevicular fluid (GCF) and the relationship between its concentration of saliva. GCF, serum and changes in periodontal health. Over an 8 day period, 10 adults with periodontal disease received orally 200 mg/day of Minocin and 10 other received 150 mg/day. The parameter evaluated included the DMF, gingival index, plaque index, crevice depth, oral soft tissue evaluation. SMA-12, CBC, prothrombin time, and concentrations of Minocin in serum, saliva and GCF. The DMF score, crevice depth, SMA-12, CBC and prothrombin time were determined on days 1 and 8. All other parameters were evaluated on days 1, 2, 3, 5 and 8. The results of this study showed that Minocin administration resulted in no significant changes in blood chemistry, blood counts and prothrombin time, was effective against oral microorganisms as shown by reductions in plaque scores, produces an improvement in gingival health, is present in serum at therapeutically effective levels when given in doses of either 200 mg or 150 mg per day and is concentrated in gingival crevicular fluid at levels 5 times as high as serum.
A 3.2 Gbps/pin 8 Gbit 1.0 V LPDDR4 SDRAM With Integrated ECC Engine for Sub-1 V DRAM Core Operation (2014)

A 1.0 V 8 Gbit LPDDR4 SDRAM with 3.2 Gbps/pin speed and integrated ECC engine for sub-1 V DRAM core is presented. DRAM internal read-modify-write operation for data masked write makes the integrated ECC engine possible in a commodity DRAM. Time interleaved latency and IO control circuits enable 1.0 V operation at target speed. To reach 3.2 Gbps with improved power efficiency over conventional mobile DRAMs, the following IO features are introduced: Low voltage swing terminated logic drivers with VOH level calibration and periodic ZQ calibration, unmatched DQ/DQS scheme and DQS oscillator for DQS tree delay tracking. This chip is fabricated in 25 nm DRAM process on 88.1 mm <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$^{2}$</tex></formula> die area.
Intravenous boluses and continuous infusions of <scp>L</scp>‐DOPA methyl ester in fluctuating patients with Parkinson's disease (1992)

In six patients with Parkinson's disease exhibiting severe "on-off" phenomena, a 200-mg intravenous bolus of either L-DOPA or of its methyl ester were equally effective in reversing motor deficits, although the duration of action of the methyl ester was shorter. There were no marked differences in pharmacokinetic parameters for L-DOPA plasma levels after administration of L-DOPA and the methyl ester. In three patients, optimal infusion rates for the maintenance of mobility were established for L-DOPA and L-DOPA methyl ester. Both drugs were able to maintain patients "on" throughout a 12-h infusion period. However, on average the optimal infusion rate of L-DOPA methyl ester was 2.7 times greater than that for L-DOPA. There was no marked difference in the plasma levels of L-DOPA achieved, but 3-O-methyl DOPA levels increased more after infusion of L-DOPA methyl ester than after infusion of L-DOPA itself. The half-life of elimination and volume of distribution of L-DOPA formed from the methyl ester were markedly increased compared with values obtained after either an intravenous bolus of methyl ester or after an intravenous infusion of L-DOPA itself. An intravenous bolus of L-DOPA methyl ester produces an equivalent magnitude of clinical response to the same dose of L-DOPA. However, higher optimal infusion rates of methyl ester than L-DOPA are required to produce continuous effect. The pharmacokinetic handling of L-DOPA methyl ester given by intravenous infusion may differ from that of L-DOPA when given by the same route.
Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally (2000)

Oxidized low density lipoprotein (LDL) has been found to exhibit numerous potentially atherogenic properties, including transformation of macrophages to foam cells. It is believed that high density lipoprotein (HDL) protects against atherosclerosis by removing excess cholesterol from cells of the artery wall, thereby retarding lipid accumulation by macrophages. In the present study, the relative rates of HDL-mediated cholesterol efflux were measured in murine resident peritoneal macrophages that had been loaded with acetylated LDL or oxidized LDL. Total cholesterol content of macrophages incubated for 24 h with either oxidized LDL or acetylated LDL was increased by 3-fold. However, there was no release of cholesterol to HDL from cells loaded with oxidized LDL under conditions in which cells loaded with acetylated LDL released about one-third of their total cholesterol to HDL. Even mild degrees of oxidation were associated with impairment of cholesterol efflux. Macrophages incubated with vortex-aggregated LDL also displayed impaired cholesterol efflux, but aggregation could not account for the entire effect of oxidized LDL. Resistance of apolipoprotein B (apoB) in oxidized LDL to lysosomal hydrolases and inactivation of hydrolases by aldehydes in oxidized LDL were also implicated. The subcellular distribution of cholesterol in oxidized LDL-loaded cells and acetylated LDL-loaded cells was investigated by density gradient fractionation, and this indicated that cholesterol derived from oxidized LDL accumulates within lysosomes. Thus impairment of cholesterol efflux in oxidized LDL-loaded macrophages appears to be due to lysosomal accumulation of oxidized LDL rather than to impaired transport of cholesterol from a cytosolic compartment to the plasma membrane.
AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast (1991)

AP17 and AP19 are the smallest polypeptide chain components of AP-2 and AP-1, the clathrin-associated protein complexes found in coated structures of the plasma membrane and Golgi apparatus of mammalian cells. cDNA clones representing the entire coding sequence of AP17 and AP19 were isolated from rat and mouse brain cDNA libraries, respectively. Determination of their nucleotide sequence predicts proteins of 142 and 158 amino acids with Mr 17,018 and 18,733. A sequence comparison of rat brain AP17 with mouse brain AP19 demonstrates that the small chains are highly related. A computer search for other related proteins has uncovered in yeast a previously unknown gene whose DNA sequence encodes a protein homologous to the small chain of AP complexes. The yeast sequence predicts Yap17p, a protein with 147 amino acids and a Mr of 17,373 that is slightly more related to the mammalian AP17 chain than to its AP19 counterpart.
Le droit de rature, droit inhérent au scrutin de liste (2012)

International audience
Combining Surface Plasmon Resonance (SPR) Spectroscopy with Surface-Enhanced Raman Scattering (SERS) (2011)

The simultaneous measurement of surface plasmon resonance (SPR) spectroscopy and surface-enhanced Raman scattering (SERS) on flat metallic surfaces is demonstrated on a relatively simple experimental setup based on the Kretschmann configuration. This setup requires only minor modifications to standard Raman microscopes, and we show that it can be applied successfully to the most common conditions of SPR spectroscopy, i.e., water-based solutions on gold films. Our results emphasize the peculiar properties of the Kretschmann configuration for spectroscopy in general and SERS measurements in particular, especially in terms of the asymmetry between excitation and collection requirements. The combination of simultaneous SPR-SERS spectroscopy opens up interesting prospects in analytical science to study, for example, reaction kinetics at surfaces under conditions which are already available in commercial SPR instruments.
Feature Extraction Method Using the Bhattacharyya Distance (2000)

In pattern classification, the Bhattacharyya distance has been used as a class separability measure. Furthemore, it is recently reported that the Bhattacharyya distance can be used to estimate error of Gaussian ML classifier within 1-2% margin. In this paper, we propose a feature extraction method utilizing the Bhattacharyya distance. In the proposed method, we first predict the classification error with the error estimation equation based on the Bhauacharyya distance. Then we find the feature vector that minimizes the classification error using two search algorithms: sequential search and global search. Experimental reslts show that the proposed method compares favorably with conventional feature extraction methods. In addition, it is possible to determine how man, feature vectors arc needed for achieving the same classification accuracy as in the original space.
assessing the health promotion needs of informal carers (2002)

How do carer support programmes meet the needs of those caring for dependent mentally ill older people? Julie Hall reviews the evidence
Mapping and planning under uncertainty in mobile robots with long-range perception (2008)

Recent advances in self-supervised learning have enabled very long-range visual detection of obstacles and pathways (to 100 meters or more). Unfortunately, the category and range of regions at such large distances come with a considerable amount of uncertainty. We present a mapping and planning system that accurately represents range and category uncertainties, and accumulates the evidence from multiple frames in a principled way. The system relies on a hyperbolicpolar map centered on the robot with a 200 m radius. Map cells are histograms that accumulate evidence obtained from a self-supervised object classifier operating on image windows. The performance of the system is demonstrated on the LAGR off-road robot platform.