gebhart/patrepeval huggingface dataset:
NASA's access to space study (1994)

A NASA study to identify and assess the major alternatives for a long range direction for space transportation is summarized. The scope of this 'access to space' study was to support all U.S. needs for space transportation for several decades into the future, including civilian, commercial, and defense needs.
Relecture des décisions thérapeutiques en RCP à travers une étude rétrospective sur l'indication de la chimiothérapie adjuvante en fonction des facteurs pronostiques chez les patientes atteintes d'un cancer du sein SBR 2, RH+, HER2- (2015)

Introduction : Bien qu'il ait été prouvé que la chimiothérapie adjuvante permettait d'améliorer la survie chez la plupart des patientes présentant un cancer du sein invasif, les indications thérapeutiques concernant les tumeurs de grade SBR 2, RH+ et HER2- restent sujettes à controverse. Matériel et méthodes : Une étude rétrospective multicentrique a été réalisée chez 163 patientes présentant un cancer du sein infiltrant de grade SBR 2, RH+, Her2-, opérées et discutées en RCP de janvier 2011 à décembre 2013, en région Picardie. L’analyse a porté sur l’association entre une décision de chimiothérapie et les facteurs pronostiques classiques (âge, envahissement ganglionnaire, taille tumorale, Ki67). L’analyse multivariée a fait suite à une analyse univariée et menée par régression logistique. L’apport des signatures génomiques a été évalué chez neuf patientes.Résultats : L’envahissement ganglionnaire (p<0.0001 ; OR=12.9 IC95% [4.3-49.1]), la taille tumorale élevée (p=0.0009 ; OR=7.8 IC95% [2.5-29.8]), l’âge jeune (p=0.0005 ; OR=0,9 IC95% [0.86-0.96]) et le Ki67 élevé (p=0.04 ; OR=2,7 IC95% [1.1-6.8]) sont associés de manière significative et indépendante à une décision de chimiothérapie après analyse multivariée. Plus de deux tiers des patientes (66,9%) ont reçu une chimiothérapie adjuvante. À l’inverse, elles n’étaient que 33% à en avoir reçu lorsqu’elles avaient bénéficié d’un test génomique. Conclusion : Les décisions de chimiothérapie adjuvante étaient homogènes et cohérentes en fonction des critères pronostiques cliniques et anatomopathologiques à disposition. Dans ce groupe à risque intermédiaire, il parait évident que les signatures génomiques puissent aider à sélectionner les patientes qui pourraient réellement bénéficier d’une chimiothérapie adjuvante en plus de l’hormonothérapie.
General theory of the Purcell-Pennypacker scattering approach and its extension to bianisotropic scatterers (1992)

Coupled volume integral equations and the long-wavelength approximation have been used to generalize the Purcell-Pennypacker technique (PPT) and the method of moments (MOM) for inhomogeneous bianisotropic scatterers. The interrelationship between the generalized PPT and the MOM has been established. The dyadic functions employed throughout can be easily interpreted in terms of matrices or as Cartesian tensors of the second rank.
Translation of GDMO/ASN.1 to Java objects for network management (2002)

In general, the necessary requirements for implementing a network management system are considered as network management protocols, object-oriented information modeling, management functions/services, and a graphical user interface (GUI) in a distributed environment. Java/sup TM/ is designed to meet the challenges of application development in the context of heterogeneous, network-wide distributed environments and provides the capabilities of simplicity, object-oriented concept, reliability, portability, multi-threading, and viewer capability. Thus, it is proper to make the development environment using Java for network management system. Especially, the translation of GDMO/ASN.1 to Java mechanism is designed and implemented for the information model of the TMN. It is used as a core facility to produce the Java objects which represent managed objects.
Effect of a bioflavonoid dietary supplement on acetaminophen-induced oxidative injury to feline erythrocytes (2000)

Oral administration of bioflavonoid antioxidants to cats at risk for oxidative stress may have a beneficial effect on their ability to resist oxidative injury to erythrocytes.
Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. (1994)

The Wilms' tumor gene, WT1, is expressed in few tissues, mainly the developing kidney, genitourinary system, and mesothelium, and in immature hematopoietic cells. To develop an understanding of the role of WT1 in development and tumorigenesis, we have identified transcriptional regulatory elements that function in transient reporter gene constructs transfected into kidney and hematopoietic cell lines. We found three transcription start sites of the WT1 gene and have identified an essential promoter region by deletion analysis. The WT1 promoter is a member of the GC-rich, TATA-less, and CCAAT-less class of polymerase II promoters. Whereas the WT1 promoter is similar to other tumor suppressor gene promoters, the WT1 expression pattern (unlike Rb and p53) is tissue-restricted. The WT1 GC-rich promoter is promiscuous, functioning in all cell lines tested, independent of WT1 expression. This finding suggests that the promoter is not tissue-specific, but that tissue-specific expression of WT1 is modulated by additional regulatory elements. Indeed, we have identified a transcriptional enhancer located 3' of the WT1 gene > 50 kilobases downstream from the promoter. This orientation-independent enhancer increases the basal transcription rate of the WT1 promoter in the human erythroleukemia cell line K562, but not in any of the other cell lines tested.
Stream function optimization for gradient coil design (2001)

This work presents a method applied to the design of short self-shielded gradient coils of cylindrical geometry. The method uses a hybrid technique that combines the simulated annealing and target field methods to optimize the standard stream functions. The optimized stream functions were parameterized using a few degrees of freedom to reduce the computing time. The optima stream function parameters are given for easy coil design purposes. The proposed approach is compared to the target field method. The main advantage of the present method over the target field method is its ability to enlarge the homogeneous gradient volume. In addition, the designs of short coils based on this approach have shown lower inductance than the coil design based on the target field method. The fast-simulated annealing technique presented in this work enables the gradient coil optimization in less than 3 min of computing time. Magn Reson Med 45:505-512, 2001.
The CD14 <sup>bright</sup> CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population (2011)

This study is the first to provide a link between the increased frequency of the CD14(bright) CD16+ monocyte subpopulation in RA and the expansion of Th17 cells, which are likely to have a role in the pathogenesis of autoimmunity.
Mean field network based qos routing scheme in wireless mesh networks (2005)

Multi-constrained quality-of-service routing (QoSR) is to find a feasible path that satisfies multiple constraints simultaneously, as an NPC problem, which is also a big challenge for wireless mesh networks. There are few methods, which can solve this problem effectively so far. In this paper, we propose a novel routing scheme based on mean field network (MFN/spl I.bar/RS) to solve this problem. This algorithm first uses a function of the wireless link's delay and capacity both of which are QoS parameters as the cost function, and then seeks to find a feasible path by mean field annealing. Because MFN/spl I.bar/RS uses a set of deterministic equations to replace the stochastic process in simulated annealing (SA), and uses saddle point approximation in the calculation of the stationary probability distribution at equilibrium, thus the convergence time is much less than the algorithm based on SA. Simulation results demonstrate that MFN/spl I.bar/RS is an effective algorithm and is very fit for wireless mesh networks where the topology may be changing constantly.
Amniotic Septostomy for the Treatment of Twin Oligohydramnios-Polyhydramnios Sequence (1998)

Amniotic septostomy is a promising new method for the management of TOPS and is associated with survival rates that are better than, or comparable to, more invasive modalities. A multicenter trial comparing septostomy to other modalities is warranted.
Rapid detection of mycobacteria in clinical specimens by using the automated BACTEC 9000 MB system and comparison with radiometric and solid-culture systems (1997)

Recovery rates of acid-fast bacilli (AFB) and the mean time to their detection from clinical specimens were determined by using the fluorescent BACTEC 9000 MB system. Data were compared to those assessed by the radiometric BACTEC 460 system and by cultivation on solid media. A total of 3,095 specimens were processed with N-acetyl-L-cysteine-NaOH by two laboratories. The contamination rates for the BACTEC 9000 MB system were 6.8% (center 1) and 9.8% (center 2). A total of 451 mycobacterial isolates were detected (Mycobacterium tuberculosis complex, n = 296; nontuberculous mycobacteria [NTM], n = 155). These isolates originated from 94 (20.8%) smear-positive and 357 (79.2%) smear-negative specimens. The BACTEC 9000 MB system was significantly better than solid media (P < 0.05) in detecting AFB, but it was less efficient than the radiometric system (P < 0.01). The BACTEC 9000 MB system plus solid media (combination A) recovered 393 (87.1%) of the isolates, while the BACTEC 460 system plus solid media (combination B) detected 430 (95.3%) of all AFB isolates. Between combination A and B there was no statistically significant difference for the detection of isolates from smear-positive specimens (P > 0.05), in contrast to the recovery of AFB from smear-negative specimens for M. tuberculosis complex, P < 0.05; for NTM, P < 0.01). The mean time to detection of M. tuberculosis complex was 12.2 days for smear-positive specimens and 18.1 days for smear-negative specimens with the BACTEC 9000 MB system; 9.3 and 15.6 days, respectively, with the BACTEC 460 system; and 21.2 and 28.4 days, respectively, with solid media. For NTM, the average detection times were 15.1, 17.3, and 31.3 days by the three methods, respectively. In conclusion, the BACTEC 9000 MB system is a rapid, less labor-intensive detection system which allows for higher levels of recovery of AFB than solid media. There is no risk of cross contamination, which is known to be the case for the BACTEC 460 system, and data management is greatly facilitated. As a whole, however, the BACTEC 9000 MB system should only be used in conjunction with solid media.
Furazolidone versus ampicillin in the treatment of traveler's diarrhea (1984)

Ninety-four U.S. students who acquired diarrhea in Mexico were treated with furazolidone (47 subjects) or ampicillin (47 subjects) on a double-blind random basis. Of 47 students, 26 (55%) who received furazolidone (100 mg four times daily for 5 days) recovered from illness within 48 h after initiation of therapy, in contrast to 15 of 47 (32%) who received ampicillin (500 mg four times daily for 5 days) (P less than 0.05). Altogether, 74% of students treated with furazolidone and 49% of those receiving ampicillin were well within 72 h (P less than 0.05). When furazolidone was compared with ampicillin, clinical illness was shortened on the average from 65 to 61 h for enterotoxigenic Escherichia coli diarrhea, from 83 to 58 h for shigellosis, from 82 to 51 h for diarrhea unassociated with a detectable agent, and from 72 to 57 h for all cases irrespective of etiology. Although not dramatically effective in the current trial, the broad spectrum of activity of furazolidone is of interest. Because of in vitro activity against Campylobacter strains and known effectiveness in treating giardiasis, furazolidone should be considered in therapy for diarrhea of unknown etiology in certain settings when laboratory processing of stools for etiological agent is not feasible.
Correlation among Morphology, Crystallinity, and Charge Mobility in OFETs Made of Quaterthiophene Alkyl Derivatives on a Transparent Substrate Platform (2011)

In this Article, we present a comprehensive study of organic field-effect transistors (OFETs) made of thin films of methyl, n-butyl, and n-hexyl end-substituted quaterthiophenes on a transparent substrate platform. This particular platform has been already used for organic light-emitting diodes (OLEDs) but rarely employed for OFETs. In perspective, this is a very promising route for the development of field-effect photonic applications such as organic light-emitting transistors (OLETs). A systematic characterization of the organic films has been made by means of atomic force microscopy (AFM) and X-ray diffraction (XRD) to correlate morphology, crystallinity and charge mobility to the alkyl chain length. In particular, a charge mobility value of 0.09 cm(2)/(V s) has been obtained in transparent OFETs with a large area channel for DH4T grown at room temperature. This mobility exceeds the one obtained on silicon-oxide substrates and is likely due to a more favorable interaction of the DH4T molecules with the PMMA layer employed as gate dielectric.
Metachromatic behaviour of dyes in solvents of high dielectric constant: the anomaly of water (1967)

The visible absorption spectrum of 1,1′-diethyl-2,2′-carbocyanine bromide has been examined in a variety of solvents of high dielectric constant. Metachromasy is exhibited only in aqueous solutions and to a much smaller extent in glycerol solutions. The results are consistent with the view that the abnormally high tendency of water molecules to self-associate is an important factor responsible for the anomalous metachromasy of dyes in water. The addition of large amounts of sucrose to aqueous solutions of Methylene Blue tends to destroy the metachromasy exhibited by this dye.
DEVELOPMENT OF AN ENZYME‐LINKED IMMUNOSORBENT ASSAY (ELISA) FOR ANALYSIS OF LISTERIOLYSIN O PRODUCED BY <i>LISTERIA MONOCYTOGENES</i><sup>1</sup> (1993)

Listeriolysin O (LLO) is a heat-labile hemolysin produced by Listeria mono-cytogenes. Its hemolytic activity has been evaluated qualitatively by sodium dodecyl sulfate (SDS) electrophoresis and immunoblotting. In this experiment, an enzyme-linked immunosorbent assay (ELISA) was developed for quantitative analysis of LLO by using Streptolysin O (SLO) and antistreptolysin O (ASO) as the reagents. The selected coating and blocking buffers were 0.05 M Tris buffer (pH 8.5) and 0.25% casein solution with phosphate-buffered saline solution + 0.05% Tween 20 (PBS-T), respectively. A relationship between ASO and antibody was achieved with 5 mg/ml ASO and a 1:1,000 dilution of conjugate. The heat stability of LLO at 48, 62, 72, and 80C was examined by using this method and compared with a traditional hemolysis assay. Although the LLO is inactivated easily at those temperatures, the protein structure was not affected at temperatures lower than 80C for 3 min, pointing to a need for both hemolysis and ELISA to be conducted in determining both the activity and presence of LLO in foods.
Development of MPO type 8-multicore fiber connector (2015)

We developed MPO type 8-MCF (56-core) connector. Rotational alignment with alignment member and absorption of protrusion difference using compressive strain were adopted. Fabricated 8-MCF connector demonstrated all core PC and connection loss < 0.7 dB.
Influence of tilt and decentration of scleral-sutured intraocular lens on ocular higher-order wavefront aberration (2006)

In eyes with scleral-sutured posterior chamber IOL, tilting of the lens induces considerable amount of ocular coma-like aberrations.
CISSP All-in-One Exam Guide, Fifth Edition (2009)

A comprehensive, up-to-date revision of the market-leading CISSP training resource

Written by Shon Harris, the number-one name in IT security certification and training, this exam guide offers complete coverage of all the material on the latest release of the Certified Information Systems Security Professional (CISSP) exam. With full treatment of all the 10 exam domains, as developed by the International Information Systems Security Certification Consortium (ISC2), this definitive tool contains learning objectives at the beginning of each chapter, sidebars with in-depth technical explanations, practice questions, and real-world scenarios.

CISSP All-in-One Exam Guide, Fifth Edition serves as both a comprehensive certification study guide and an essential on-the-job reference. The CD-ROM includes more than 250 simulated practice questions in a Windows-based test engine, an electronic book, and video training from the author.

Table of contents
Chapter 1: Reasons to Become a CISSP
Chapter 2: Security Trends
Chapter 3: Operation Security
Chapter 4: Access Control Methods
Chapter 5: Telecommunications and Network Security
Chapter 6: Cryptography
Chapter 7: Applications and Systems Development Security
Chapter 8: Business Continuity Planning and Disaster Recovery
Chapter 9: Physical Security
Chapter 10: Laws, Investigations, and Ethics
Chapter 11: Security Management Practices
Chapter 12: Security Architecture and Models
Glossary
Expression of the Protein Tyrosine Phosphatase β2 Gene in Mouse Erythroleukemia Cells Induces Terminal Erythroid Differentiation (1996)

We have cloned cDNA for protein tyrosine phosphatase beta2, which had been implicated in erythroid differentiation of mouse erythroleukemia cells. Expression of cDNA constructs, in which beta2 cDNA is placed under the control of mouse metallothionein-I promoter, by ZnCl2 converted a significant portion (20 to 38%) of the cells to erythroid-like cells, which is 25-50% of the erythroid differentiation efficiency observed by conventional erythroid-inducing agents. Furthermore, introduction and expression of altered protein tyrosine phosphatase beta2 cDNA constructs designed to produce the enzyme lacking the phosphatase activity inhibited erythroid differentiation by 100-20%, depending upon the concentration of erythroid-inducing agents employed. These results strongly suggest that protein tyrosine phosphatase beta2 is involved in triggering erythroid differentiation in mouse erythroleukemia cells.
Chaos in the pulse spacing of passive Q-switched all-solid-state lasers (2010)

We report the experimental and theoretical verification that, in a diode-pumped Nd:YAG+Cr:YAGQ-switched laser, the instabilities in the pulse spacing ("jitter") are ruled by low-dimensional deterministic chaos. From our experimental time series, we determine the embedding and fractal dimensions of the attractor, as well as the values of the Lyapunov exponents. We also present a simplified theoretical description in terms of a map of the same universality class as the logistic map, which explains the bifurcations' cascade and the period-three window of stability observed. The achieved characterization of the dynamics and its main parameters opens a door to effective ways to reduce the jitter, which is of practical interest, through mechanisms of control of chaos. Conversely, the difficulty in the prediction of the interpulse spacing makes this system attractive for high power, robust FM chaotic laser cryptography in free-space propagation.
Architectural techniques to accelerate multimedia applications on general-purpose processors (2001)

General-purpose processors (GPPs) have been augmented with multime-dia extensions to improve performance on multimedia-rich workloads. These extensions operate in a single instruction multiple data (SIMD) fashion to ex-tract data level parallelism in multimedia and digital signal processing (DSP)applications. This dissertation consists of a comprehensive evaluation of theexecution characteristics of multimedia applications on SIMD enhanced GPPs,detection of bottlenecks in the execution of multimedia applications on SIMD enhanced GPPs, and the design and implementation of architectural techniques to eliminate and alleviate the impact of the various bottlenecks to acceleratemultimedia applications. This dissertation identifies several bottlenecks in the processing of SIMD enhanced multimedia and DSP applications on GPPs. It is found that approxi-mately 75-85% of instructions in the dynamic instruction stream of media work-loads are not performing useful computations but merely supporting the useful computations by performing address generation, address transformation/data reorganization, loads/stores, and loop branches. This leads to an under-utilization of the SIMD computation units with only 1-12% of the peak SIMD throughput being achieved. This dissertation proposes the use of hardware support to efficiently exe-cute the overhead/supporting instructions by overlapping them with the useful computation instructions. A 2-way GPP with SIMD extensions augmented with the proposed MediaBreeze hardware significantly outperforms a 16-way SIMD GPP without MediaBreeze hardware on multimedia kernels. On multimedia ap-plications, a 2-/4-way SIMD GPP augmented with MediaBreeze hardware is superior to a 4-/8-way SIMD GPP without MediaBreeze hardware. The per-formance improvements are achieved at an area cost that is less than 0.3% of current GPPs and power consumption that is less than 1% of the total processor power without elongating the critical path of the processor.
The Cryogenic Diffusion Pump - An Advanced Design for Fusion Reactor Primary Pumping and Fuel Processing (1992)

A re-evaluation of the characteristics of the intermediate flow regime with simultaneous thermal accommodation has shown the full potential of the Cryogenic Diffusion Pump for Fusion Reactor applications. A device with a characteristic diameter of 1m will have a pumping speed of 150m3s−1 for Deuterium at an inlet pressure of 2 × 10−2 Pa (Reactor Burn phase) and 400m3s−1 at an inlet pressure of 0.1 Pa (Reactor Dwell phase). Simultaneously, it separates impurities, Hydrogen isotopes and Helium and compresses the Helium. The Helium compression ratio (already proven to be ≥25 for 3% Helium in D2) can be further enhanced by additional D2 or He driven Diffusion Pump and Ejector stages. The latter feature will also simplify pumping requirements for the Helium Glow Discharge scenario: recirculation of Helium at 0.1 Pa (driven by D2 or He Ejector) and simultaneous removal of DT and impurities by cryocondensation requires no mechanical pump at all or only small turbomolecular-drag pump combinations for He jet drive. The design offers superior tritium compatibility: all metal, fully bakeable, it avoids use of absorbers and argon for helium pumping, thereby reducing overall tritium inventory both in the pump itself and by replacing major fuel clean-up facilities. The advantages of using the Cryogenic Diffusion Pump in a Fusion Reactor Vacuum System are discussed in detail.