gebhart/patrepeval huggingface dataset:
Practical Railway Engineering (2005)

Station Layout Rolling Stock Depots and Workshops Track Earthworks, Drainage and Fencing Bridges and Structures Tunnels and Tunnelling Electrification Signalling and Train Control Systems and Communications Lifts, Escalators and Pumps Ventilation and Draught Relief Future Trends.
ASIC Design of Fast IP Lookup for Next Generation IP Router (2005)

One of the prime designs for the next generation IP routers is the IP-lookup mechanism. The IP lookup has become a major performance bottleneck for the routers. In this paper, we propose a complete hardware architecture which includes searching, updating, inserting, and deleting functions. A simple hash hardware design is used to reduce the lookup time, and a CAM is also used to solve the collision problems effectively. The ASIC includes search unit, memory controller, 1M-byte cache and 3.18 Kbytes CAM for a 32000 entries routing table. The searching, updating and deleting functions only need 1 cycle and it is 96.88% to chance to hit the correct next hop in the first cycle.
Mobile agent programming in Ajanta (2003)

The paper gives an overview of Ajanta, a Java based system for mobile agent programming. We outline the Ajanta architecture, and discuss the basic elements that comprise an agent based application. Ajanta's programming environment is defined in terms of a set of primitive operations for agent creation, dispatch, migration and remote control. Agents can access server resources using a proxy based access control mechanism. We describe a scheme for agent migration based on the composition of some basic migration patterns which incorporate exception handling mechanisms. Finally, we present two agent based distributed applications implemented using the Ajanta system. One is a middleware which supports file sharing over the Internet and the other is a distributed calendar manager.
Worksite Wellness Programs: Incremental Comparison of Screening and Referral Alone, Health Education, Follow-up Counseling, and Plant Organization (1991)

The program models that offered short-term interventions promoted through local media suffered in comparison with models that included personal outreach to people at risk, a variety of health improvement intervention modalities, and ongoing follow-up counseling to help people make decisions and sustain health improvements.
La actualidad del teatro de Lope de Vega en la década de 1930: presencia en la cartelera española y recepción (2021)

El objetivo del presente artículo es repasar la presencia del teatro de Lope de Vega en la cartelera española de la década de 1930, con especial atención a la madrileña, atendiendo a la recepción de sus puestas en escena y a la interpretación que se dio a sus piezas. En estos años, paulatinamente, el teatro clásico comenzó a ofrecer muestras del avance escenográfico y la renovación dramatúrgica que los críticos venían reclamando para la escena española desde la década anterior: en este sentido, el teatro de Lope de Vega adquiere especial relevancia, pues, además de tratarse de uno de los autores áureos más populares de la época, su obra conoció especial atención por la celebración del tercer centenario de su muerte en 1935. Además, las turbulentas circunstancias sociopolíticas de estos años conectaron una de sus piezas, Fuente Ovejuna, con la actualidad española del momento.
Write and read circuit for memristor analog resistance switching (2017)

Size scaling CMOS transistors are known to improve cost, speed, and power per chip that results in high performance IC. However, too small transistor size can degrade transistor performance thus become limitation to CMOS scaling. One way to overcome this limitation is by incorporating CMOS with memristor; a device that offers small size, low power, nonvolatile characteristic with switching ability and is compatible with CMOS technology. In this research, memristor resistance write circuit (RWC) and read circuit (RRC) are presented. A pulse-coded memristor programming method is adopted in RWC design. It uses 2 sets of switches to decreases or increases resistance by supplying positive or negative pulse. Plus, the longer width of supply signal, the bigger changes of resistance. Next, two types of RRC are presented; voltage read circuit and current read circuit. Former circuit consists of trans-impedance amplifier and resistor. Output voltage from amplifier expresses memristor resistance value. When voltage supply is negative pulse, memristor resistance increases thus V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">out</inf> gradually decreases and otherwise. Latter circuit consists of amplifier and CMOS transistor to read the current from memristor that express memristor resistance. When memristor resistance changes, the current also changes. Set of current mirror is added to enable memristor current to be copied to other circuit. A current sample and hold circuit is added to keep current information when there is no voltage supply. Result shows first RWC successfully program resistance of memristor either to increase or decrease. Second, voltage read circuit can express resistance value in voltage form but have negative output voltage that not very applicable. Third, current read circuit can give current output based on memristor resistance and applicable with other circuits.
Evolving prototype rules and genetic algorithm in a combustion control (2002)

All approaches to rule-based control have relied upon a pre-classification of the state-space for their success. Given a classification of the state-space, either an individual control action or a whole set of control actions can be learnt. But quality of control is limited by the quality of the state-space classification. When no classification is specified, a more challenging problem is how to arrive at the most suitable partitioning of the state-space with its associated control actions. The approach presented in this paper is to generate prototype rules. Instead of learning a control action for every point encountered, a genetic algorithm is used to learn control actions for a set of limited number of prototype states and the nearest neighbour matching is employed to decide which of the rules to fire in any particular situation when controlling a system. The example of a simulated multiple burner combustion optimization is used to demonstrate this approach.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Non-Mendelian Dominant Maternal Effects Caused by CRISPR/Cas9 Transgenic Components in<i>Drosophila melanogaster</i> (2016)

The CRISPR/Cas9 system has revolutionized genomic editing. The Cas9 endonuclease targets DNA via an experimentally determined guide RNA (gRNA). This results in a double-strand break at the target site . We generated transgenic <i>Drosophila melanogaster</i> in which the CRISPR/Cas9 system was used to target a <i>GAL4</i> transgene <i>in vivo</i> To our surprise, progeny whose genomes did not contain CRISPR/Cas9 components were still capable of mutating <i>GAL4</i> sequences. We demonstrate this effect was caused by maternal deposition of Cas9 and gRNAs into the embryo, leading to extensive <i>GAL4</i> mutations in both somatic and germline tissues. This serves as a cautionary observation on the effects of maternal contributions when conducting experiments using genomically encoded CRISPR/Cas9 components. These results also highlight a mode of artificial inheritance in which maternal contributions of DNA editing components lead to transmissible mutant defects even in animals whose genomes lack the editing components. We suggest calling this a dominant maternal effect to reflect it is caused by the gain of maternally contributed products. Models of CRISPR-mediated gene drive will need to incorporate dominant maternal effects in order to accurately predict the efficiency and dynamics of gene drive in a population.
Affinity labeling of the carbohydrate binding site of the lectin discoidin I using a photoactivatable radioiodinated monosaccharide (1987)

N-(4-Azidosalicyl)galactosamine (GalNASA), a photoactivatable, radioiodinatable analogue of N-acetylgalactosamine (GalNAc), has been prepared and characterized. We have used this reagent for labeling of the carbohydrate binding site of discoidin I, an endogenous lectin produced by Dictyostelium discoideum. GalNASA behaved as a ligand for discoidin I, as judged by its ability to compete in an assay measuring the carbohydrate binding activity of discoidin I. In this assay, it exhibited a Ki,app of 800 microM, comparable to that of GalNAc. The Ki,app of GalNASA decreased to 40 microM upon prior photolysis with ultraviolet light. In contrast, N-(4-azidosalicyl)ethanolamine produced no inhibition of carbohydrate binding regardless of photolysis. Covalent labeling of discoidin I with 125I-GalNASA was entirely dependent upon ultraviolet light. A portion of the labeling, representing 40-60% of the total, was sensitive to reagents which were known to inhibit carbohydrate binding by discoidin I, including GalNAc, asialofetuin, and ethylenediaminetetraacetic acid. N-Acetylglucosamine, which is not a ligand of discoidin I, was without effect. As a control, no carbohydrate-sensitive labeling was observed upon incubation of 125I-GalNASA with bovine serum albumin. The carbohydrate-sensitive fraction of discoidin I photolabeling with 125I-GalNASA exhibited a Kd of 15-40 microM, in agreement with the Ki,app of prephotolyzed GalNASA observed in the carbohydrate binding assay. Some labeling occurred if 125I-GalNASA was photolyzed prior to incubation with discoidin I, suggesting the involvement of long-lived species in the labeling reaction. Partial proteolytic digestion of photolabeled discoidin I revealed specific fragments whose labeling was completely blocked by GalNAc.(ABSTRACT TRUNCATED AT 250 WORDS)
Topology of LcnD, a protein implicated in the transport of bacteriocins from Lactococcus lactis (1996)

Four in-frame translational fusions to both the reporter proteins beta-galactosidase and alkaline phosphatase support a topological model of LcnD, a protein implicated in the transport of several bacteriocins from Lactococcus lactis, in which the N-terminal part is located intracellularly and one transmembrane helix spans the cytoplasmic membrane.
Aspect windows, 3-D visualizations, and indirect comparisons of information retrieval systems (1998)

We built two Information Retrieval systems that were targeted for the TREC-6 "aspect oriented" retrieval track. The systems were built to test the usefulness of different visualizations in an interactive IR setting-in particular, an "aspect window" for the chosen task, and a 3-D visualization of document inter-relationships. We studied 24 users of the system in order to investigate: whether the systems were more effective than a control system, whether experienced users outperformed novices, whether spatial reasoning ability was a good predictor of effective use of 3-D, and whether the systems could be compared indirectly via a control system. Our results show substantial differences in user performance are related to spatial reasoning ability and to a lesser degree other traits. We also obtained markedly different results from the direct and indirect comparisons. 1
Acyl homoserine lactone-based quorum sensing in a methanogenic archaeon (2012)

Acyl homoserine lactone (AHL)-based quorum sensing commonly refers to cell density-dependent regulatory mechanisms found in bacteria. However, beyond bacteria, this cell-to-cell communication mechanism is poorly understood. Here we show that a methanogenic archaeon, Methanosaeta harundinacea 6Ac, encodes an active quorum sensing system that is used to regulate cell assembly and carbon metabolic flux. The methanogen 6Ac showed a cell density-dependent physiology transition, which was related to the AHL present in the spent culture and the filI gene-encoded AHL synthase. Through extensive chemical analyses, a new class of carboxylated AHLs synthesized by FilI protein was identified. These carboxylated AHLs facilitated the transition from a short cell to filamentous growth, with an altered carbon metabolic flux that favoured the conversion of acetate to methane and a reduced yield in cellular biomass. The transcriptomes of the filaments and the short cell forms differed with gene expression profiles consistent with the physiology. In the filaments, genes encoding the initial enzymes in the methanogenesis pathway were upregulated, whereas those for cellular carbon assimilation were downregulated. A luxI-luxR ortholog filI-filR was present in the genome of strain 6Ac. The carboxylated AHLs were also detected in other methanogen cultures and putative filI orthologs were identified in other methanogenic genomes as well. This discovery of AHL-based quorum sensing systems in methanogenic archaea implies that quorum sensing mechanisms are universal among prokaryotes.
ChemInform Abstract: Recent Advances in the Chemistry of Taxol (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The Challenge of Replicability Toward a New Paradigm for Urban Shelter in Developing Countries (1983)

During the 1970s, the problem of urban growth in developing countries received more international attention than ever before. Increasing attention on the urban sector focused on the problem of urban shelter, the need to provide shelter at low cost to a rapidly growing urban population.. Two approaches to solving the problem were the sites and services concept and the slum improvement or upgrading approach. Each of these implies that the government should do what the people cannot do for themselves, i.e. provide infrastructure networks, but that housing construction is a private matter. The primary limitation of these approaches was the fact that they remained very small in scope in relation to the scale of the demand for housing in most cities. Other areas of concern include training of personnel, development of the building materials industry, encouragement of community participation, development of housiung finance institutions, and exchange of information and technology. It is clear that the public sector can help resolve these issues. However, the critical issue is the establishment of a capacity to perform these functions.
Prospects of photosensitization in control of pathogenic and harmful micro-organisms (2009)

Photosensitization is a treatment involving the interaction of the two nontoxic factors, photoactive compound and visible light, which in the presence of oxygen results in the selective destruction of the target cell. Different micro-organisms, such as multidrug-resistant bacteria, yeasts, microfungi and viruses, are susceptible to this treatment. Therefore, a photosensitization phenomenon might open a new avenue for the development of nonthermal, effective and ecologically friendly antimicrobial technology, which might be applied for food safety.
Molecular mimicry between GQ<sub>1b</sub> ganglioside and lipopolysaccharides of <i>Campylobacter jejuni</i> isolated from patients with Fisher's syndrome (1994)

We isolated Campylobacter jejuni from 2 patients with Fisher's syndrome subsequent to enteritis. Crude lipopolysaccharide fractions were extracted from the bacteria and separated by thin-layer chromatography. Monoclonal antibodies to GQ1b ganglioside (GMR13 and 7F5) reacted with both lipopolysaccharide fractions, indicating that the lipopolysaccharides bear the GQ1b epitope. This is the first report of molecular mimicry between neural tissue components and the antecedent infectious agents of Fisher's syndrome.
Triplet–Triplet Annihilation Upconversion in CdS-Decorated SiO<sub>2</sub> Nanocapsules for Sub-Bandgap Photocatalysis (2014)

This study reports the first successful nanoscale encapsulation of triplet-triplet annihilation upconversion (TTA-UC) medium within a rigid silica shell using a self-assembly microemulsion process. These newly synthesized nanocapsules present a few critical advances that could be instrumental for a wide range of aqueous-based photonics applications, including photocatalysis, artificial photosynthesis, and bioimaging. The nanocapsules form a homogeneous suspension that can produce intense, diffuse UC emission in water without deoxygenation, closely resembling conventional TTA-UC processes that have been performed in deoxygenated organic solvents. The silica shell provides sites for further surface modification, which allows, when combined with its nanoscale dimension and structural rigidity, this TTA-UC system to acquire various useful functionalities. A benchmark TTA-UC pair, palladium(II) tetraphenyltetrabenzoporphyrin as a sensitizer and perylene as an acceptor, was used to demonstrate efficient red-to-blue (635 nm, 1.95 eV → 470 nm, 2.6 eV) upconversion in the oxygen-rich aqueous phase. The nanocapsule surface was further functionalized with cadmium sulfide nanoparticles (Eg = 2.4 eV) to demonstrate sub-bandgap sensitization and subsequent aqueous-phase catalytic oxidation.
[No Title] (1994)

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Proteomic Characterization of Human Milk Fat Globule Membrane Proteins during a 12 Month Lactation Period (2011)

The milk fat globule membrane (MFGM) contains proteins which have been implicated in a variety of health benefits. Milk fat globule membrane proteins were isolated from human milk during a 12 month lactation period and subjected to in-solution digestion and liquid chromatography tandem mass spectrometry analysis. Data were pooled, and our results showed that 191 proteins were identified. Relative quantification of the identified MFGM proteins during the course of lactation was performed by label free spectral counting and differentiation expression analysis, which showed some proteins decreasing during the course of lactation whereas some increased or remained at a relatively constant level. The human MFGM proteins are distributed between intracellular, extracellular, and membrane-associated proteins, and they are mainly involved in cell communication and signal transduction, immune function, metabolism and energy production. This study provides more insights into the dynamic composition of human MFGM proteins, which in turn will enhance our understanding of the physiological significance of MFGM proteins.
Extracellular ATP causes lysis of mouse thymocytes and activates a plasma membrane ion channel (1991)

Extracellular ATP (ATPo) caused a concentration-dependent lysis of mouse thymocytes. Lysis, as judged by release of the cytosolic enzyme lactate dehydrogenase, was preceded by depolarization of the plasma membrane and by Ca2+ influx. Both Na+ uptake (which sustained plasma membrane depolarization) and Ca2+ influx showed (1) the same dependence on the ATPo concentration; (2) the same nucleotide specificity; and (3) the same Hill coefficient. However, whereas the rise in the cytosolic free Ca2+ concentration ([Ca2+]i) was fully inhibited by the known Ca2+ blocker verapamil, plasma membrane depolarization was enhanced under these conditions. Plasma membrane depolarization was greater and was shifted to lower ATPo concentrations in the absence of extracellular Ca2+ (Ca2+o), whereas the rise in [Ca2+]i was greater in Na(+)-free media. Plasma membrane depolarization also occurred in Na(+)-free choline- or methylglucamine-containing media, and was potentiated by chelation of free divalent ions with EDTA, supporting previous reports pointing to ATP4-as the active species. Among a number of purine and pyrimidine nucleotides, only adenosine 5'-[gamma-thio]triphosphate and ADP were partially effective. Furthermore, ethidium bromide (Mr 380), Lucifer Yellow (Mr 463) and Eosin Yellowish (Mr 692) did not permeate through the ATPo-activated channel. These findings suggest that lytic effects of ATPo in mouse thymocytes depend on the activation of a membrane channel with low selectivity for cations and an Mr cut-off of 200.
Chiral molecular recognition in monolayers of diastereomeric N-acylamino acid methyl esters at the air/water interface (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChiral molecular recognition in monolayers of diastereomeric N-acylamino acid methyl esters at the air/water interfaceJonathan G. Heath and Edward M. ArnettCite this: J. Am. Chem. Soc. 1992, 114, 12, 4500–4514Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://pubs.acs.org/doi/10.1021/ja00038a009https://doi.org/10.1021/ja00038a009research-articleACS PublicationsRequest reuse permissionsArticle Views433Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Using RankBoost to compare retrieval systems (2005)

This paper presents a new pooling method for constructing the assessment sets used in the evaluation of retrieval systems. Our proposal is based on RankBoost, a machine learning voting algorithm. It leads to smaller pools than classical pooling and thus reduces the manual assessment workload for building test collections. Experimental results obtained on an XML document collection demonstrate the effectiveness of the approach according to different evaluation criteria.
Microring Resonator Based Photonic Circuits: Analysis and Design (2007)

Microring and microdisk resonators are used in photonic circuits to perform filter functions, serve as band- limited mirrors in lasers, compensate for dispersion and group delay distortion, are used in multiplexers in telecommunication systems, and a number of other applications such as medical instrumentation, biosensing, interferometry, to name a few. This paper outlines some challenges and solutions in this relatively new and prolific discipline.
PERMA and the building blocks of well-being (2018)

Seligman (2011) hypothesized that PERMA (Positive Emotion, Engagement, Relationships, Meaning, and Accomplishment) are the elements of well-being. Goodman, Disabato, Kashdan & Kaufmann (2017) reported strong evidence that subjective well-being is the final common path of such elements and their data are entirely consistent with Seligman’s hypothesis. They argued, incorrectly however, that he suggested that PERMA constituted a different kind of well-being rather than just its building blocks. The complicated issue, one that transcends psychometrics, of how to decide on elements of well-being is discussed.