gebhart/patrepeval huggingface dataset:
Metalloproteinases in the intestine of patients with Crohn's disease (1990)

Conference Article| October 01 1990 Metalloproteinases in the intestine of patients with Crohn's disease CAROLINE J. BAILEY; CAROLINE J. BAILEY *Department of Biochemistry, University of Manchester, Medical School, Manchester M13 9PT, U.K. Search for other works by this author on: This Site PubMed Google Scholar ROSALIND M. HEMBRY; ROSALIND M. HEMBRY †Strangeways Research Laboratory, CB1 4RN, Cambridge U.K. Search for other works by this author on: This Site PubMed Google Scholar ANNE ALEXANDER; ANNE ALEXANDER ‡Department of Surgery, University of Manchester, Medical School, Manchester M13 9PT, U.K. Search for other works by this author on: This Site PubMed Google Scholar C. ADRIAN SHUTTLEWORTH; C. ADRIAN SHUTTLEWORTH *Department of Biochemistry, University of Manchester, Medical School, Manchester M13 9PT, U.K. Search for other works by this author on: This Site PubMed Google Scholar MICHAEL E. GRANT; MICHAEL E. GRANT *Department of Biochemistry, University of Manchester, Medical School, Manchester M13 9PT, U.K. Search for other works by this author on: This Site PubMed Google Scholar MILES L. IRVING MILES L. IRVING ‡Department of Surgery, University of Manchester, Medical School, Manchester M13 9PT, U.K. Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Received: March 02 1990 Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1990 Biochemical Society1990 Biochem Soc Trans (1990) 18 (5): 896–897. https://doi.org/10.1042/bst0180896 Article history Received: March 02 1990 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation CAROLINE J. BAILEY, ROSALIND M. HEMBRY, ANNE ALEXANDER, C. ADRIAN SHUTTLEWORTH, MICHAEL E. GRANT, MILES L. IRVING; Metalloproteinases in the intestine of patients with Crohn's disease. Biochem Soc Trans 1 October 1990; 18 (5): 896–897. doi: https://doi.org/10.1042/bst0180896 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: TIMP, tissue inhibitor of metalloproteinases, FITC, fluorescein isothiocyanate This content is only available as a PDF. © 1990 Biochemical Society1990 Article PDF first page preview Close Modal You do not currently have access to this content.
Thermochemistry of Paddle Wheel MOFs: Cu-HKUST-1 and Zn-HKUST-1 (2013)

Metal-organic framework (MOF) porosity relies upon robust metal-organic bonds to retain structural rigidity upon solvent removal. Both the as-synthesized and activated Cu and Zn polymorphs of HKUST-1 were studied by room temperature acid solution calorimetry. Their enthalpies of formation from dense assemblages (metal oxide (ZnO or CuO), trimesic acid (TMA), and N,N-dimethylformamide (DMF)) were calculated from the calorimetric data. The enthalpy of formation (ΔHf) of the as-synthesized Cu-HKUST-H2O ([Cu3TMA2·3H2O]·5DMF) is -52.70 ± 0.34 kJ per mole of Cu. The ΔHf for Zn-HKUST-DMF ([Zn3TMA2·3DMF]·2DMF) is -54.22 ± 0.57 kJ per mole of Zn. The desolvated Cu-HKUST-dg [Cu3TMA2] has a ΔHf of 16.66 ± 0.51 kJ/mol per mole Cu. The ΔHf for Zn-HKUST-amorph [Zn3TMA2·2DMF] is -3.57 ± 0.21 kJ per mole of Zn. Solvent stabilizes the Cu-HKUST-H2O by -69.4 kJ per mole of Cu and Zn-HKUST-DMF by at least -50.7 kJ per mole of Zn. Such strong chemisorption of solvent is similar in magnitude to the strongly exothermic binding at low coverage for chemisorbed H2O on transition metal oxide nanoparticle surfaces. The strongly exothermic solvent-framework interaction suggests that solvent can play a critical role in obtaining a specific secondary building unit (SBU) topology.
Association between plasticized starch and polyesters: Processing and performances of injected biodegradable systems (2001)

Abstract Different formulations of wheat thermoplastic starch (TPS) have been processed with various plasticizer/starch ratios and moisture contents. The biodegradable polyesters tested are polycaprolactone (PCL), polyester amide (PEA), polybutylene succinate adipate (PBSA) and polybutylene adipate co terephtalate (PBAT). TPS and polyesters are melt blended in different proportions by extrusion and then injected to obtain dumbbell specimens. Various properties are evaluated such as the mechanical properties (tensile and impact tests), and the hydrophilic character with contact angle measurements. Additionally, uniaxial shrinkage is evaluated. Results show that the addition of polyester to TPS increases the dimensional post‐injection stability. Blend modulus values are close to the results of the classical rule of mixture. Elongation at break, resilience values and SEM observations seem to give some indications about the compatibility between both polymeric systems. PBAT and PEA present better results than PCL and PBSA. Contact angle measurement show that we have a drastic increase of the hydrophobic character from 10% of polyester in the blend. The different combinations of TPS and polyesters give a wide range of mechanical behavior for compostable materials, to be developed in specific applications.
Newly developed RELACS process and materials for 65nm node device and beyond (2005)

To meet market's demands for high performance devices, we have studied various resolution enhancement techniques (RET), such as off axis illumination, phase shift masks, optical proximity correction, resist thermal reflow, and chemical shrinkage process etc. RELACS (resolution enhancement lithography assisted by chemical shrink) is one of the most useful technology among chemical shrink processes. We have introduced KrF-RELACS process into mass production phase. However, in the case of ArF lithography, we are not able to be satisfied with shrinkage performance of conventional RELACS materials. To improve this matter, we paid attention to the chemically difference of side chain between KrF resist and ArF resist polymers.
A relationship between nuclear spin relaxation in the laboratory and rotating frames for dipolar and quadrupolar relaxation (1992)

Density operator theory of nuclear spin relaxation due to fluctuating magnetic dipole or electric quadrupole interactions is based on a differential equation for the density operator which, in the weak collision limit, depends on the spectral density functions of the dipolar or quadrupolar fluctuations. It is shown that the differential equation for relaxation in the rotating frame may be expressed in a similar form to that for relaxation in the laboratory frame. Expressions for magnetization recoveries in the rotating frame can then be simply deduced from the laboratory frame expressions by replacing the spectral density functions in the laboratory frame results by linear combinations of spectral density functions. The method is applied to single-exponential relaxation for the dipolar mechanism and to single- and multiple-exponential relaxation for the quadrupole mechanism for both longitudinal and transverse magnetization recoveries.
Synthetic studies of trans-clerodane diterpenoids and congeners: stereocontrolled total synthesis of (.+-.)-avarol (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic studies of trans-clerodane diterpenoids and congeners: stereocontrolled total synthesis of (.+-.)-avarolAluru S. Sarma and Partha ChattopadhyayCite this: J. Org. Chem. 1982, 47, 9, 1727–1731Publication Date (Print):April 1, 1982Publication History Published online1 May 2002Published inissue 1 April 1982https://pubs.acs.org/doi/10.1021/jo00348a025https://doi.org/10.1021/jo00348a025research-articleACS PublicationsRequest reuse permissionsArticle Views469Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Characterization of Immunological Cross-Reactivity between Enterotoxigenic Escherichia coli Heat-Stable Toxin and Human Guanylin and Uroguanylin (2014)

Enterotoxigenic Escherichia coli (ETEC) expressing the heat-stable toxin (ST) (human-type [STh] and porcine-type [STp] variants) is among the five most important enteric pathogens in young children living in low- and middle-income countries. ST mediates diarrheal disease through activation of the guanylate cyclase C (GC-C) receptor and is an attractive vaccine target with the potential to confer protection against a wide range of ETEC strains. However, immunological cross-reactivity to the endogenous GC-C ligands guanylin and uroguanylin is a major concern because of the similarities to ST in amino acid sequence, structure, and function. We have investigated the presence of similar epitopes on STh, STp, guanylin, and uroguanylin by analyzing these peptides in eight distinct competitive enzyme-linked immunosorbent assays (ELISAs). A fraction (27%) of a polyclonal anti-STh antibody and an anti-STh monoclonal antibody (MAb) cross-reacted with uroguanylin, the latter with a 73-fold-lower affinity. In contrast, none of the antibodies raised against STp, one polyclonal antibody and three MAbs, cross-reacted with the endogenous peptides. Antibodies raised against guanylin and uroguanylin showed partial cross-reactivity with the ST peptides. Our results demonstrate, for the first time, that immunological cross-reactions between ST and the endogenous peptides can occur. However, the partial nature and low affinity of the observed cross-reactions suggest that the risk of adverse effects from a future ST vaccine may be low. Furthermore, our results suggest that this risk may be reduced or eliminated by basing an ST immunogen on STp or a selectively mutated variant of STh.
Adenosine A<sub>1</sub> receptors regulate bone resorption in mice: Adenosine A<sub>1</sub> receptor blockade or deletion increases bone density and prevents ovariectomy‐induced bone loss in adenosine A<sub>1</sub> receptor–knockout mice (2010)

These results suggest that the adenosine A(1) receptor may be a useful target in treating diseases characterized by excessive bone turnover, such as osteoporosis and prosthetic joint loosening.
Recognizing Thousands of Legal Entities through Instance-based Visual Classification (2014)

This paper considers the problem of recognizing legal entities in visual contents in a similar way to named-entity recognizers for text documents. Whereas previous works were restricted to the recognition of a few tens of logotypes, we generalize the problem to the recognition of thousands of legal persons, each being modeled by a rich corporate identity automatically built from web images. We introduce a new geometrically-consistent instance-based classification method that is shown to outperform state-of-the-art techniques on several challenging datasets while being much more scalable. Further experiments performed on an automatic web crawl of 5,824 legal entities demonstrates the scalability of the approach.
Patterns of 4th graders' literacy events in Web page development (2003)

This study describes in-class and home literacy events that occur when students work in groups to create web pages as evidence of learning the academic content that was presented within a fourth grade classroom. The constructivist approach to learning was the underpinning idea examined as well as its connection to technology and group work. Data were collected in a variety of ways to obtain a picture, as comprehensive as possible, of the oral, listening, viewing, and written on-task communication and interactions that occurred. As the in-class and home literacy events emerged, the competencies and strategies that students used while interacting with traditional text were uncovered. These events encompass the strategies that the students used after they encountered the text and had to modify it for one reason or another. These literacy events illustrate how the Internet supports reading and writing in the elementary classroom when it is utilized as a tool for promoting instruction.
Planning, Execution and Results of the Precision Airdrop Technology Conference and Demonstration (2003) (2005)

Abstract : During the week of 3-7 November 2003, the second Precision Airdrop Technology Conference and Demonstration (PATCAD) was executed at the US Army Yuma Proving Ground in Yuma Arizona. The PATCAD 2003 was facilitated by the US Army Natick Soldier Center (NSC) and partially sponsored by numerous other organizations to include: US Army PM-Force Sustainment Systems, US Air Force Air Mobility Command, US Special Operations Command (SOCOM), US Army Tactical UAV Office, Deputy Under Secretary for Defense for Advanced Systems and Concepts (DUSD-AS&C), Foreign Comparative Test Office, US Army Yuma Proving Ground (YPG), and ECIII. This paper will describe in detail the rationale, timing, and planning required to execute a PATCAD, provide an overview of the program and systems demonstrated and displayed, and describe the results of the event. In addition, related future events that are being planned at the time of this paper submission, specifically PATCAD 2005 and NATO related efforts, will be presented. It will also describe the safety aspects and technical considerations for executing a PATCAD and the airdrop logistics and lessons learned from this and related events.
Reasoning and Ontologies for Personalized E-Learning in the Semantic Web. (2004)

The challenge of the semantic web is the provision of distributed information with well-defined meaning, understandable for different parties. Particularly, applications should be able to provide individually optimized access to information by taking the individual needs and requirements of the users into account. In this paper we propose a framework for personalized e-Learning in the semantic web and show how the semantic web resource description formats can be utilized for automatic generation of hypertext structures from distributed metadata. Ontologies and metadata for three types of resources (domain, user, and observation) are investigated. We investigate a logic-based approach to educational hypermedia using TRIPLE, a rule and query language for the semantic web.
No data left behind (2017)

The typical enterprise data architecture consists of several actively updated data sources (e.g., NoSQL systems, data warehouses), and a central data lake such as HDFS, in which all the data is periodically loaded through ETL processes. To simplify query processing, state-of-the-art data analysis approaches solely operate on top of the local, historical data in the data lake, and ignore the fresh tail end of data that resides in the original remote sources. However, as many business operations depend on real-time analytics, this approach is no longer viable. The alternative is hand-crafting the analysis task to explicitly consider the characteristics of the various data sources and identify optimization opportunities, rendering the overall analysis non-declarative and convoluted.
MIBlet, logically partitioned resource controller, in SNMP/SMI and CORBA for open switching architecture (2002)

For more rapid and flexible service creation, the Multiservice Switching Forum (MSF) has begun to define an open intra-switch interface. The objective of the MSF is to define an architecture that separates the control and user/data plane aspects of an ATM-capable multiservice network. Another objective is to establish an extensible framework to new adaptation and switching technologies. However MSF's activities regarding the management areas are rare except for simply mentioning the use of SNMP across all the planes and future use of CORBA. In this paper, we simply describe MSF's architecture and its the management aspect. Then we propose to partition the managed resources, which is either shared or dedicated by each signalling controller, into a set of logically managed units: MIBlets. We define components of the MIBlet and propose to use the MIBlet as a common resource interface based on SNMP/SMI. Finally we also show the IDL mapping in case of CORBA based communications across all the planes. The one of purpose of this paper is to show modelling of resources in SNMP/SMI with CORBA which will help to develop the system rapidly, and in a standard and more interoperable way.
Synthesis of All Four Stereoisomers of Antibacterial Component of Avocado (1982)

Starting from (S)-2,2-dimethyl-1,3-dioxolane-4-ethanal, all four stereoisomers of 16-heptadecene-1,2,4-triol were synthesized. In comparison with synthetic products, the naturally occurring antibacterial triol in the avocado fruit was determined as (2R, 4R)-16-heptadecene-1,2,4-triol.
Design of a Three-Axis Articulated Tool Head With Parallel Kinematics Achieving Desired Motion/Force Transmission Characteristics (2010)

This paper addresses the design issue of a three-axis tool head with three-PRS parallel kinematics (P, R, and S standing for prismatic, revolute, and spherical joint, respectively) by considering their orientation capability and motion/force transmission. The content presented here is actually an improvement on the dimensional optimization of articulated tool heads with parallel kinematics, with emphasis on the three-PRS design to solve the problem of orientational capability. An index that can evaluate the effectiveness of the motion/force transmission is introduced. The orientation capability with which the mechanism has high motion/force transmission capability is then defined. The procedure searching the link lengths with which the mechanism has a high orientation capability and good effectiveness of motion/force transmission is finally presented.
Family of human Na<sup>+</sup>,K<sup>+</sup>‐ATPase genes Structure of the gene for the catalytic subunit (αIII‐form) and its relationship with structural features of the protein (1988)

The primary structure of a gene of the Na+, K+-ATPase multigenic family in the human genome has been determined. The gene corresponds to a hypothetical alpha III-form of the enzyme catalytic subunit. The gene comprises over 25,000 bp, and its protein coding region includes 23 exons and 22 introns. Possible correlation between structural features of the protein and location of introns in the gene are discussed.
Analysis and Design of Repetitive Control Systems using the Regeneration Spectrum (1990)

The absolute and relative stability of continuous-time SISO repetitive control systems is examined here using a function of frequency termed the regeneration spectrum. The regeneration spectrum is easily computed and is related to important of the characteristic root distribution of such systems, for large values of the time delay. The regeneration spectrum is combined with other frequency domain measures of control system performance such as the sensitivity and complementary sensitivity functions to obtain improved insight into the trade-offs in repetitive control system design. The result is a more rational approach to repetitive control system design and is illustrated by an example.
Traveltime calculation and prestack depth migration in tilted transversely isotropic media (2004)

Abstract The principal objective of our work is to develop a technique for prestack depth migration in tilted transversely isotropic (TTI) media in which the axis of symmetry is not vertical and may be spatially varying. Such models are required to image seismic data in geologically complex regions such as the Canadian Foothills. We have developed a 2D Kirchhoff integral-based migration algorithm in which the traveltime computation comprises the major task. Among the existing traveltime computation algorithms such as ray tracing with interpolation, ray bending, and eikonal solvers, a direct or a brute force approach of traveltime computation is generally highly robust. We have modified a direct method of first-arrival P-wave traveltime computation in 2D media that accounts for TTI. The algorithm requires that the group velocity be computed at each gridpoint, using either an analytic solution or by an approximate Fourier series expansion. The P-wave traveltime contours computed for complex geologic models show the pronounced effects from TTI media. Our results, using laboratory P-wave data collected over a physical model of an anisotropic thrust sheet, reveal that a 2D Kirchhoff migration based on our traveltime algorithm (TTI model) images the structure beneath the thrust sheet very well. The vertical transversely isotropic (assuming a vertical axis of symmetry) or isotropic imaging introduces false anticlinal structures. We compare our results with those obtained by a recursive-extrapolation method and find that our approach images the underside of one of the thrust sheets better.
Effects of Carbon Dioxide on Bacterial Growth Parameters in Milk as Measured by Conductivity (2003)

Inhibition of bacterial growth by dissolved carbon dioxide (CO2) has been well established in many foods including dairy foods. However, the effects of dissolved CO2 on specific growth parameters such as length of lag phase, time to maximum growth rate, and numbers of organisms at the stationary phase have not been quantified for organisms of concern in milk. The effect of dissolved CO2 concentrations of 0.6 to 61.4 mM on specific bacterial growth parameters in raw or single organism inoculated sterile milk was determined at 15 degrees C by conductance. Commingled raw or sterile milks were amended to a final concentration of 0.5 mg/ml each of urea and arginine HCl. Sterile milks were inoculated singly with one of six different microorganisms to a final concentration of approximately 10(2) to 10(3) cfu/ml; raw milk was adjusted to a final indigenous bacterial population of approximately 10(3) cfu/ml. Conductivity of the milk was recorded every 60 s over 4 to 5 d in a circulating apparatus at 15 degrees C. Conductivity values were fit to Gompertz equations and growth parameters calculated. Conductance correlated with plate counts and was satisfactory for monitoring microbial growth. Data fit the Gompertz equation with high correlation (R2 = 0.96 to 1.00). In all cases, dissolved CO2 significantly inhibited growth of raw milk bacteria, influencing lag, exponential, and stationary growth phases as well as all tested monocultures.