gebhart/patrepeval huggingface dataset:
A Development of Evaluation Index for Bus Demand-Elastic Schedule Management (2009)

Although enormous data have been collected in major cities (Korea) by APTS(Advanced Public Transit Systems), most of studies related to bus schedule management evaluation have confined to headway adherence and on-time performance. Therefore, bus operation management have been very lack of using APTS data. This study uses coefficient of correlation to evaluate bus company's schedule management level. However, direct application of coefficient of correlation has inequitable problem because of many limitation(number of vehicle, headway, etc). and so variable calibration method was developed and applied to cope with these problems. Thus, demand-elastic management evaluation index was developed. For verifying the equity of developed index, it is applied to Seoul bus routes. It is expected for the developed index to contribute into the demand-elastic management of bus schedule.
Targeting CCL2 with Systemic Delivery of Neutralizing Antibodies Induces Prostate Cancer Tumor Regression<i>In vivo</i> (2007)

The identification of novel tumor-interactive chemokines and the associated insights into the molecular and cellular basis of tumor-microenvironment interactions have continued to stimulate the development of targeted cancer therapeutics. Recently, we have identified monocyte chemoattractant protein 1 (MCP-1; CCL2) as a prominent regulator of prostate cancer growth and metastasis. Using neutralizing antibodies to human CCL2 (CNTO888) and the mouse homologue CCL2/JE (C1142), we show that treatment with anti-CCL2/JE antibody (2 mg/kg, twice weekly i.p.) attenuated PC-3Luc-mediated overall tumor burden in our in vivo model of prostate cancer metastasis by 96% at 5 weeks postintracardiac injection. Anti-CCL2 inhibition was not as effective as docetaxel (40 mg/kg, every week for 3 weeks) as a single agent, but inhibition of CCL2 in combination with docetaxel significantly reduced overall tumor burden compared with docetaxel alone, and induced tumor regression relative to initial tumor burden. These data suggest an interaction between tumor-derived chemokines and host-derived chemokines acting in cooperation to promote tumor cell survival, proliferation, and metastasis.
High-Performance MoS2 Field-Effect Transistors Enabled by Chloride Doping: Record Low Contact Resistance (0.5 kohm*um) and Record High Drain Current (460 uA/um) (2014)

In this paper, we report a novel chemical doping technique to reduce the contact resistance (Rc) of transition metal dichalcogenides (TMDs) - eliminating two major roadblocks (namely, doping and high Rc) towards demonstration of high-performance TMDs field-effect transistors (FETs). By using 1,2 dichloroethane (DCE) as the doping reagent, we demonstrate an active n-type doping density > 2*1019 cm-3 in a few-layer MoS2 film. This enabled us to reduce the Rc value to a record low number of 0.5 kohm*um, which is ~10x lower than the control sample without doping. The corresponding specific contact resistivity (pc) is found to decrease by two orders of magnitude. With such low Rc, we demonstrate 100 nm channel length (Lch) MoS2 FET with a drain current (Ids) of 460 uA/um at Vds = 1.6 V, which is twice the best value reported so far on MoS2 FETs.
Silicon compilation: The future is now: Silicon compilers liberate the integrated circuit design process (1986)

Agreat deal of interest has recently been generated about a new integrated circuit (IC) design methodology called silicon compilation. Silicon compilation allows IC designers and system experts to quickly develop sure-fire, sophisticated, application-specific ICs with silicon efficiencies approaching those of handcrafted ICs.
NMR Crystallography of Aluminum Carbide: Impurities in the Reagent and Improved <sup>27</sup>Al NMR Tensors (2020)

The structure of aluminum carbide (from two different manufacturers) has been interrogated by 27Al solid-state NMR in an effort to accurately characterize the material. Quadrupolar line shapes for 27Al sites such as these are important to catalogue, as efforts are underway to employ NMR crystallography tools to understand and predict both solid-state structures and perturbations to these that are relevant to NMR analyses. Impurities present in both of the samples are revealed to be aluminum oxycarbides, as well as an aluminum metal impurity in one and aluminum nitride in another—potentially important information for groups employing aluminum carbide in syntheses or in other applications. Triple-quantum magic-angle spinning (3Q-MAS) 27Al NMR was employed to help determine the quadrupolar parameters of the two crystallographically inequivalent aluminum sites in Al4C3. Revised values for the quadrupolar tensors of this material were measured and simulated through use of CASTEP-NMR.
Interaction of Hepatitis C Virus Core Protein with Viral Sense RNA and Suppression of Its Translation (1999)

To clarify the binding properties of hepatitis C virus (HCV) core protein and its viral RNA for the encapsidation, morphogenesis, and replication of HCV, the specific interaction of HCV core protein with its genomic RNA synthesized in vitro was examined in an in vivo system. The positive-sense RNA from the 5' end to nucleotide (nt) 2327, which covers the 5' untranslated region (5'UTR) and a part of the coding region of HCV structural proteins, interacted with HCV core protein, while no interaction was observed in the same region of negative-sense RNA and in other regions of viral and antiviral sense RNAs. The internal ribosome entry site (IRES) exists around the 5'UTR of HCV; therefore, the interaction of the core protein with this region of HCV RNA suggests that there is some effect on its cap-independent translation. Cells expressing HCV core protein were transfected with reporter RNAs consisting of nt 1 to 709 of HCV RNA (the 5'UTR of HCV and about two-thirds of the core protein coding regions) followed by a firefly luciferase gene (HCV07Luc RNA). The translation of HCV07Luc RNA was suppressed in cells expressing the core protein, whereas no significant suppression was observed in the case of a reporter RNA possessing the IRES of encephalomyocarditis virus followed by a firefly luciferase. This suppression by the core protein occurred in a dose-dependent manner. The expression of the E1 envelope protein of HCV or beta-galactosidase did not suppress the translation of both HCV and EMCV reporter RNAs. We then examined the regions that are important for suppression of translation by the core protein and found that the region from nt 1 to 344 was enough to exert this suppression. These results suggest that the HCV core protein interacts with viral genomic RNA at a specific region to form nucleocapsids and regulates the expression of HCV by interacting with the 5'UTR.
6-Chloro-6-dehydro-A-nor Steroids with Progestational Activity. 7α-Chloro-A-nor Steroids (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT6-Chloro-6-dehydro-A-nor Steroids with Progestational Activity. 7α-Chloro-A-nor SteroidsPatrick A. Diassi, Seymour D. Levine, and Raymond M. PalmereCite this: J. Med. Chem. 1967, 10, 4, 551–556Publication Date (Print):July 1, 1967Publication History Published online1 May 2002Published inissue 1 July 1967https://pubs.acs.org/doi/10.1021/jm00316a011https://doi.org/10.1021/jm00316a011research-articleACS PublicationsRequest reuse permissionsArticle Views52Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tracking Multiple Occluding People by Localizing on Multiple Scene Planes (2009)

Occlusion and lack of visibility in crowded and cluttered scenes make it difficult to track individual people correctly and consistently, particularly in a single view. We present a multi-view approach to solving this problem. In our approach we neither detect nor track objects from any single camera or camera pair; rather evidence is gathered from all the cameras into a synergistic framework and detection and tracking results are propagated back to each view. Unlike other multi-view approaches that require fully calibrated views our approach is purely image-based and uses only 2D constructs. To this end we develop a planar homographic occupancy constraint that fuses foreground likelihood information from multiple views, to resolve occlusions and localize people on a reference scene plane. For greater robustness this process is extended to multiple planes parallel to the reference plane in the framework of plane to plane homologies. Our fusion methodology also models scene clutter using the Schmieder and Weathersby clutter measure, which acts as a confidence prior, to assign higher fusion weight to views with lesser clutter. Detection and tracking are performed simultaneously by graph cuts segmentation of tracks in the space-time occupancy likelihood data. Experimental results with detailed qualitative and quantitative analysis, are demonstrated in challenging multi-view, crowded scenes.
Butylation of the tryptophan indole ring: a side reaction during the removal of t-butyloxycarbonyl and t-butyl protecting groups in peptide synthesis (1970)

Yu. B. Alakhov, A. A. Kiryushkin, V. M. Lipkin and G. W. A. Milne, J. Chem. Soc. D, 1970, 406b DOI: 10.1039/C2970000406B
Recent Advances in DNA Sequence Analysi (1975)

(1975). Recent Advances in DNA Sequence Analysi. CRC Critical Reviews in Biochemistry: Vol. 2, No. 4, pp. 455-512.
Operational Characteristics of an IPM-Type Bearingless Motor With 2-Pole Motor Windings and 4-Pole Suspension Windings (2017)

A bearingless motor (BelM) integrates the characteristics of an electric motor and a magnetic bearing. Typically, a surface-mounted permanent magnet (SPM)-type BelM with a ring magnet magnetized in parallel is employed for high-speed operation. It is noteworthy that a carbon fiber bandage is needed to fix the ring magnet. However, when an SPM-type BelM is applied to a high-output motor, it becomes difficult to generate sufficient suspension force because of the wide magnetic gap arising from the carbon fiber bandage and the ring magnet. In addition, the manufacturing cost for the large-scale ring magnet and the carbon fiber bandage is high. Therefore, to realize a high-output and high-speed BelM at a low cost, we have focused on an interior permanent magnet (IPM)-type BelM with 2-pole motor windings and 4-pole suspension windings. Moreover, a rotor structure for suppressing suspension force ripple arising in the IPM-type BelM has been proposed based on a three-dimensional finite element analysis. In this study, a prototype of the IPM-type BelM with the proposed rotor structure is produced. Experiments with this prototype show that the proposed rotor structure is effective in reducing suspension-force ripple. Additionally, the operational characteristics of the prototype are shown in detail.
Effect of thermal and redox initiator on emulsion copolymerization of styrene - : butyl acrylate and comparison of paint properties (2006)

Emulsion copolymerization of styrene with butylacrylate was carried out by thermal and redox initiator. The effect of initiator on molecular weight of the polymer and performance of surface coatings has been described.
Learning-Based Offloading of Tasks with Diverse Delay Sensitivities for Mobile Edge Computing (2019)

The ever-evolving mobile applications need more and more computing resources to smooth user experience and sometimes meet delay requirements. Therefore, mobile devices (MDs) are gradually having difficulties to complete all tasks in time due to the limitations of computing power and battery life. To cope with this problem, mobile edge computing (MEC) systems were created to help with task processing for MDs at nearby edge servers. Existing works have been devoted to solving MEC task offloading problems, including those with simple delay constraints, but most of them neglect the coexistence of deadline-constrained and delay- sensitive tasks (i.e., the diverse delay sensitivities of tasks). In this paper, we propose an actor-critic based deep reinforcement learning (ADRL) model that takes the diverse delay sensitivities into account and offloads tasks adaptively to minimize the total penalty caused by deadline misses of deadline-constrained tasks and the lateness of delay-sensitive tasks. We train the ADRL model using a real data set that consists of the diverse delay sensitivities of tasks. Our simulation results show that the proposed solution outperforms several heuristic algorithms in terms of total penalty, and it also retains its performance gains under different system settings.
Transmission Characteristics of ultra-broadband multimode Cr-doped fibers (2010)

Transmission characteristics of 300-nm broadband multimode Cr-doped fiber (MMCDF) is reported. The MMCDF may be used as a broadband optical amplifier for the entire 1300–1600 nm spectral range of low-loss windows of silica fibers.
Linear and nonlinear energy harvesters for powering pacemakers from heart beat vibrations (2011)

Linear and nonlinear piezoelectric devices are introduced to continuously recharge the batteries of the pacemakers by converting the vibrations from the heartbeats to electrical energy. The power requirement of the pacemakers is very low. At the same time, after about 10 years from the original implantation of the pacemakers, patients have to go through another surgical operation just to replace the batteries of their pacemakers. We investigate using vibration energy harvesters to significantly increase the battery life of the pace makers. The major source of vibrations in chest area is due to heartbeats. Linear low frequency and nonlinear mono-stable and bi-stable energy harvesters are designed according to especial signature of heart vibrations. The proposed energy harvesters are robust to variations of heart beat frequency and can meet the power requirement of the pacemakers.
Heparin suppresses sgk, an early response gene in proliferating vascular smooth muscle cells (1997)

Vascular smooth muscle cell (VSMC) hyperplasia plays a central role in chronic and acute vascular pathology including arteriosclerosis and restenosis following vascular surgery. The glycosaminoglycans of the heparan sulfate class, including heparin, inhibit VSMC proliferation in animals and in culture. Heparin binds to high affinity sites on the cell surface, selectively modulates mitogenic signal transduction pathway(s), and rapidly alters transcription of several genes. To further explore the molecular mechanisms responsible for this growth inhibition, we have employed the differential display technique to identify heparin-regulated genes. Here we demonstrate that heparin inhibits the expression of the early response gene sgk (serum and glucocorticoid-regulated kinase). The expression of sgk is not inhibited by chondroitin sulfate, a nonantiproliferative glycosaminoglycan, suggesting that sgk suppression may play a functional role in the antiproliferative effect of heparin. This idea is strengthened by the finding that heparin does not inhibit sgk expression in VSMCs resistant to the antiproliferative effect of heparin or in vascular endothelial cells which are unresponsive to heparin. Expression of sgk mRNA diminishes with increasing concentrations of heparin. Finally, sgk expression is not suppressed by other growth inhibitors such as transforming growth factor-β1 (TGF-β1) and interferon-β (IFN-β), suggesting separate and distinct effects of these growth inhibitors on the mitogenic pathway. J. Cell. Physiol. 173:371–379, 1997. © 1997 Wiley-Liss, Inc.
An Introduction to Antiepileptic Drugs (2005)

In recent years, the number of commercially available antiepileptic drugs (AEDs) has increased steadily. Although this may complicate management choices, it also offers welcome new options to individualize treatment more effectively. Because each of the available AEDs differs from others in many clinically relevant properties, opportunities to tailor drug treatment to the characteristics of the individual patient have never been greater. Properties that are especially important in drug selection in patients with epilepsy include spectrum of efficacy in different seizure types, adverse effects profile, pharmacokinetic properties, susceptibility to cause or be a target of clinically important drug-drug interactions, ease of use, and cost. Other factors that need to be considered in tailoring drug choice include availability of user-friendly pediatric formulations, and potentially favorable effects on co-morbid conditions. In fact, a number of AEDs are efficacious and widely prescribed in additional indications, particularly psychiatric disorders, migraine prophylaxis, and neuropathic pain. Recently, advances have been made in understanding the mechanisms of actions of AEDs at the molecular level. While a fully mechanistic approach to the clinical use of these agents is not yet feasible, knowledge of mechanisms of action offers useful clues in predicting their efficacy profile and spectrum of potential adverse effects.
Sensing and control for automated robotic edge deburring (1994)

This paper describes the sensing and control elements of a system for automated robotic edge deburring. The deburring path, automatically generated bp a task planner, is corrected on-line by an active end effector with the objective of controlling the chamfer depth. The sensing system combines the information from force and vision sensors during deburring to provide an improved depth measurement. The vision sensor is then used to verify the deburring performance during an inspection pass. The control system incorporates a new form of adaptive Generalized Predictive Control (GPC) combined with learning control, termed GPC with Learning (GPCL). The system is tested through computer simulations and deburring experiments. The experiments were performed on steel parts with one-dimensional (1-D) and two-dimensional (2-D) edges. For the 1-D edges the depth's standard deviation measured on-line was 0.015 mm with nonadaptive GPC, 0.009 mm with adaptive GPC, and 0.006 mm with adaptive GPCL. With adaptive GPCL and the 2-D edge the deviation was 0.017 mm. This was confirmed by the inspection pass measurements which reported a mean of 0.39 mm and a deviation of 0.019 mm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Xengine (2008)

XACML has become the de facto standard for specifying access control policies for various applications, especially web services. With the explosive growth of web applications deployed on the Internet, XACML policies grow rapidly in size and complexity, which leads to longer request processing time. This paper concerns the performance of request processing, which is a critical issue and so far has been overlooked by the research community. In this paper, we propose XEngine, a scheme for efficient XACML policy evaluation. XEngine first converts a textual XACML policy to a numerical policy. Second, it converts a numerical policy with complex structures to a numerical policy with a normalized structure. Third, it converts the normalized numerical policy to tree data structures for efficient processing of requests. To evaluate the performance of XEngine, we conducted extensive experiments on both real-life and synthetic XACML policies. The experimental results show that XEngine is orders of magnitude more efficient than Sun PDP, and the performance difference between XEngine and Sun PDP grows almost linearly with the number of rules in XACML policies. For XACML policies of small sizes (with hundreds of rules), XEngine is one to two orders of magnitude faster than the widely deployed Sun PDP. For XACML policies of large sizes (with thousands of rules), XEngine is three to four orders of magnitude faster than Sun PDP.
Kernel Mechanisms for Supporting Differentiated Services and Content-Aware Request Distribution in Web Clusters Providing Multiple Services (2010)

In this paper, we have designed and implemented a kernel-level Web-based QoS (WQoS) mechanism that could efficiently support differentiated services when serving multiple diverse types of Web requests in a cluster-based Web server system. Our mechanism is implemented at kernel level to effectively reduce the number of protection domain switches and data copying between kernel space and user space to accelerate response time. We also use a new content-aware request distribution policy to dispatch requests efficiently in Web clusters providing multiple types of services. Experimental results demonstrate that the Web cluster with our proposed WQoS mechanism can not only efficiently serve multiple types of service requests but also ensure that all requests with high priority can conform to Service Level Agreement (SLA) by dropping acceptable percentage of requests with minor importance during system overload.
Computational method for simulation of trunk motion : towards a theoretical based quantitative assessment of trunk performance (1999)

Quantitative assessment of trunk muscle performance is important in documenting the extent of impairment and disability due to low back disorders (LBD). The statistical pattern recognition problem of classifying LBD patients and normal subjects based on dynamic trunk performance has been data driven. To provide clinical insight for interpretation of the distinctive features in the movement profiles, we have suggested an optimization-based approach for simulation of dynamic point-to-point sagittal trunk movement. The effect of strenght impairment on movement patterns was simulated based on minimizing different physical cost functions: Energy, Jerk, Peak Torque, Impulse, and Work. During unconstrained simulations, the velocity patterns of all models are predicted, while time to peak velocity is distinct for each cost function. The significant differences between unimpaired optimal movement profiles were diminished by imposing an 80% reduction in extensor muscle strength. The results indicate that the search for finding the objective function being used by central nervous system is an ill-posed problem since were are never sure if we have included all the active constraints in the simulation. The four application areas of this study are: 1) providing optimized trajectories for bio-feedback to patients during the rehabilitation process; 2) training workers to lift safely; 3) estimating the task demand based on the global description of the job; and 4) aiding the engineering evaluation to develop ergonomic and work-place interventions which needed to accommodate individuals with prior disability.
Cross-linked protein crystals by glutaraldehyde and their applications (2015)

The mechanism of cross-linked protein crystals using glutaraldehyde, and their properties and applications are discussed in detail.
Amplified reflection, transmission, and self-oscillation in real-time holography (1981)

A theory of phase conjugation in asymmetric materials that allow a phase shift between the grating and the light-interference pattern is developed. We find that when this phase is nonzero, maximum phase-conjugate reflectivity occurs for unequal pump intensities. The conditions for self-oscillation are studied.