gebhart/patrepeval huggingface dataset:
A streaming narrow-band algorithm: interactive computation and visualization of level sets (2004)

Deformable isosurfaces, implemented with level-set methods, have demonstrated a great potential in visualization and computer graphics for applications such as segmentation, surface processing, and physically-based modeling. Their usefulness has been limited, however, by their high computational cost and reliance on significant parameter tuning. This paper presents a solution to these challenges by describing graphics processor (GPU) based algorithms for solving and visualizing level-set solutions at interactive rates. The proposed solution is based on a new, streaming implementation of the narrow-band algorithm. The new algorithm packs the level-set isosurface data into 2D texture memory via a multidimensional virtual memory system. As the level set moves, this texture-based representation is dynamically updated via a novel GPU-to-CPU message passing scheme. By integrating the level-set solver with a real-time volume renderer, a user can visualize and intuitively steer the level-set surface as it evolves. We demonstrate the capabilities of this technology for interactive volume segmentation and visualization.
Enhanced secretion and low temperature stabilization of a hyperthermostable and Ca2+-independent α-amylase of Geobacillus thermoleovorans by surfactants (2003)

The secretion of Ca2+-independent hyperthermostable alpha-amylase was enhanced in the presence of certain anionic and non-ionic detergents in the medium. Furthermore, the surfactants stabilized the enzyme during preservation at 4 degrees C. The use of this enzyme in starch hydrolysis eliminates the addition of Ca2+ in starch liquefaction and its subsequent removal by ion exchange from sugar syrups.
Adaptive Cross Approximation for MOM Matrix Fill for PC Problem Sizes to 157000 Unknowns (2005)

Recent work on sparse MOM codes for PC applications has reduced LU matrix factorization time to significantly less than matrix fill for problem unknowns approaching 200,000. This paper reports on the use and results of applying the recently developed adaptive cross approximation for significantly reducing MOM matrix fill time. Results suggest that when problem sizes approach 500,000 unknowns, matrix fill can be reduced from 100 to 10 hours on a modern PC.
Angeli selvaggi. Martin Scorsese Jonathan Demme c/o Hollywood U.S.A. (collana "Streamers") (1995)

Prima monografia internazionale sul regista Jonathan Demme, di cui si analizzano i film, la storia, l'impatto sulla cultura, la storia americana attraverso l'analisi comparata con la filmografia scorsesiana. Alle dettagliate analisi testuali si aggiungono interviste inedite a David Byrne e Martin Scorsese, e filmografie complete. Prefazione al volume del regista statunitense Roger Corman, pp. 9-11.
Prescient paper: multimedia document creation with document image matching (2004)

A system is described for creating paper documents that show images of presentation slides and bar codes that point to a multimedia recording of a presentation that has not yet occurred. An image-matching algorithm applied after a presentation determines when each slide was displayed. These time-stamps map the bar codes onto commands that control a multimedia player. We describe the system infrastructure that allows us to prepare such prescient documents and the document image-matching algorithm that enables the mapping of bar codes onto the times when slides were displayed. This provides a multimedia annotation tool that requires no electronic device at capture time.
Anti-Diabetic Effects of a<i>Coptis chinensis</i>Containing New Traditional Chinese Medicine Formula in Type 2 Diabetic Rats (2011)

The Chinese formula Tang-Min-Ling (TML), an improved product of the decoction of Dachaihu which has a history of more than 2000 years, has main constituents of Coptis chinensis Franch, Scutellaria baicalensis Georgi, Rheum officinale Baill and Bupleurum chinense DC. A multi-central randomized controlled investigation performed previously by us has showed that TML has positive effects on regulating glycometabolism in type 2 diabetes (T2DM) patients, but the mechanisms remain unclear. Using Otsuka Long-Evans Tokushima Fatty (OLETF) rats as an animal model with rosiglitazone as a positive control, we were able to detect TML's effect on the serum glucose, serum lipid, serum leptin and adiponcetin after oral administration for 12 weeks. We were also able to detect the insulin resistance level by a glucose clamp test and study the mechanisms of TML in improving insulin resistance by detecting skeletal muscle AMP-activated protein kinase (AMPK) and glucose transporter 4 (GLUT4). Results showed that TML significantly reduced the glucose area under a curve of the oral glucose tolerance test, and had a positive effect in regulating serum lipid metabolism. TML treatment also significantly reduced the serum leptin level, but it had no effect on the serum adiponectin level. The AMPK enzymatic activity and GLUT4 expression in Skeletal Muscle were also upregulated in the TML group. The results suggest that the Chinese medicine TML, which contains Coptis chinensis Franch as one of its components, improves glycometabolism and its possible mechanisms may involve in improvement of insulin resistance of OLETF rats.
Phase separation as a key to a thermoelectric high efficiency (2012)

This work elucidates the possible reasons for the outstanding, but never reproduced thermoelectric properties of the doped Ti(0.5)Zr(0.25)Hf(0.25)NiSn Heusler compounds. The structural investigations done via synchrotron X-ray diffraction measurements and scanning electron microscope measurements, which clearly show that the microstructure consists of three temperature stable C1(b) phases with possible semi-coherent interfaces, are presented. The exceptional thermoelectric properties are due to this intrinsic phase separation. It is possible to reproduce the high Figure of Merit values with ZT = 1.2 at 830 K. Furthermore, the influence of doping different elements on the Sn position in this Heusler material system is investigated.
Single-pass redundancy addition and removal (2001)

Redundancy-addition-and-removal is a rewiring technique which for a given target wire w/sub t/ finds a redundant alternative wire w/sub a/. Addition of w/sub a/ makes w/sub t/ redundant and hence removable without changing the overall circuit functionality. Incremental logic restructuring based on this technique has been used in many applications. However, the search for valid alternative wires requires trial-and-error redundancy testing of a potentially large set of candidate Wires. We study the fundamental theory behind this technique and propose a new reasoning scheme which directly identifies alternative wires without performing trial-and-error tests. Experimental results show up to 15 times speedup in comparison to the best techniques in literature.
Experimental validation of control for a positioning stage by feedback error learning (2011)

This paper considers precision positioning of a stage. To compensate uncertainties of the stage, feedback error learning (FEL) is employed. In FEL algorithm, parameters of feedback error learning are updated by using an output of a feedback controller. After learning, the feedforward controller with an inverse system of a plant is obtained. To shorten learning time, implementation methods of FEL are proposed. In our methods, free parameters in the feedforward controller are determined by using the inverse system. Furthermore, information on the inverse system is utilized for the learning. Proposed methods are demonstrated by experiments with the stage.
Support for power efficient mobile video playback on simultaneous hybrid display (2012)

Mobile devices, such as smartphones, e-books, and tablets, have limited battery capability because of the constraint of battery size and mobility requirement. However the large color displays on those devices put more tensions on this situation as the displays consume a large portion of the total battery power. A TOLED-EPD hybrid display that integrates a transparent OLED (TOLED) with an electrophoretic display (EPD) has been emerging to reduce the energy usage of displays. The technology displays information selectively on one of the displays based on the update rate of content, thus reduces the energy usage. In this paper, we propose a design of mobile video playback, Decoder4Hybrid, for the hybrid displays. The proposed approach supports encoded video playback based on the update frequency of each block, which is exploited by the hybrid display controller to determine which display should be used to show a MPEG encoded block. A fast DCT-based heuristic algorithm is proposed to detect the changes between frames at block level with minimal computation cost. Experimental results show that the proposed approach can save up to 40% power with acceptable video quality.
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure) (2019)

"The committee elected to focus this document on the prevention of HF and on the diagnosis and management of chronic HF in the adult patient with normal or low LVEF. It specifically did not consider acute HF, which might merit a separate set of guidelines and is addressed in part in the ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction (8) and the ACC/AHA 2003 Update of the Guidelines for the Management of Unstable Angina and Non-ST Elevation Myocardial Infarction (9). We have also excluded HF in children, both because the underlying causes of HF in children differ from those in adults and because none of the controlled trials of treatments for HF have included children. We have not considered the management of HF due to primary valvular disease [see ACC/AHA Guidelines on the Management of Patients With Valvular Heart Disease (10)] or congenital malformations, and we have not included recommendations for the treatment of specific myocardial disorders (e.g., hemochromatosis, sarcoidosis, or amyloidosis). These practice guidelines are intended to assist healthcare providers in clinical decision making by describing a range of generally acceptable approaches for the prevention, diagnosis, and management of HF. The guidelines attempt to define practices that meet the needs of most patients under most circumstances. However, the ultimate judgment regarding the care of a particular patient must be made by the healthcare provider in light of all of the circumstances that are relevant to that patient. These guidelines do not address cost-effectiveness from a societal perspective. The guidelines are not meant to assist policy makers faced with the necessity to make decisions regarding the allocation of finite healthcare resources. In fact, these guidelines assume no resource limitation. They do not provide policy makers with sufficient information to be able to choose wisely between options for resource allocation. The various therapeutic strategies described in this document can be viewed as a checklist to be considered for each patient in an attempt to individualize treatment for an evolving disease process. Every patient is unique, not only in terms of his or her cause and course of HF, but also in terms of his or her personal and cultural approach to the disease. Guidelines can only provide an outline for evidence-based decisions or recommendations for individual care; these guidelines are meant to provide that outline."
Mutational and expressional analyses of <scp><i>SPOP</i></scp>, a candidate tumor suppressor gene, in prostate, gastric and colorectal cancers (2012)

Mounting evidence exists that alterations of ubiquitination processes are involved in cancer pathogenesis. Speckle-type POZ protein (SPOP) is a key adaptor for Cul3-based ubiquitination process. Recent studies reported that SPOP may be a tumor suppressor gene (TSG) and somatic mutation of SPOP was detected in prostate cancer (PCA). The aim of this study was to see whether alterations of SPOP protein expression and somatic mutation of SPOP gene are features of cancers. In this study, we analyzed SPOP somatic mutation in 45 gastric (GC), 45 colorectal cancer (CRC) and 45 PCA by single-strand conformation polymorphism (SSCP). Also, we analyzed SPOP protein expression in 60 GC, 60 CRC and 60 PCA by immunohistochemistry. Overall, we detected three somatic missense mutations of SPOP gene in the coding sequences (p.Ser14Leu, p.Tyr87Cys and p.Phe133Leu). The mutations were observed in two PCA and one CRC. Of note, the p.Phe133Leu was a recurrent mutation reported in an earlier study. In the immunohistochemistry, SPOP protein was expressed in normal gastric, colonic and prostate epithelial cells, whereas it was lost in 30% of GC, 20% of CRC and 37% of PCA. Our data indicate that loss of SPOP expression was common in GC, CRC and PCA, but somatic mutation of SPOP in this study was rare in these tumors. Also, the data provide a possibility that loss of expression of SPOP gene might play a role in cancer pathogenesis by altering TSG functions of SPOP.
Healthy and confident children (2011)

The Play, Talk, Read programme, that has successfully encouraged thousands of parents to do just that more often with their children, will be rolled out throughout Scotland over the coming year.
Implementation of GaAs E/D HEMT analog components for oversampling analog/digital conversion (1994)

The paper presents design considerations and implementation of analog components, including an operational amplifier, latched comparator, 1 bit D/A converter and second-order modulator, for a fully differential delta-sigma modulation oversampling A/D converter in a 0.5 /spl mu/m GaAs E/D HEMT technology. On-wafer measurements demonstrate that the second-order modulator achieves a 60 dB dynamic range at a Nyquist conversion rate of 5.0 MHz with a sampling frequency of 500 MHz.
Electrostatic Discharge and Electrical Breakdown Study of the Head–Disk Interface in a Hard Disk Drive (2004)

A systematic and comprehensive procedure for understanding electrostatic discharge and electrical breakdown at the head-disk interface in a hard disk drive is described. First, the resistance, breakdown and field emission behavior for the individual and combined carbon overcoat films on the disk and slider was determined through current versus voltage testing. Second, different electrostatic mechanisms that can produce a voltage difference between the disk and slider or read transducer were studied. Results are explained in terms of the relative time constants for the voltage on the head and disk. It is concluded that a potential difference between the disk and recording head as little as 2 V can result in electrical breakdown damage at the head-disk interface.
ELISA-LOC: lab-on-a-chip for enzyme-linked immunodetection (2010)

A miniature 96 sample ELISA-lab-on-a-chip (ELISA-LOC) was designed, fabricated, and tested for immunological detection of Staphylococcal Enterotoxin B (SEB). The chip integrates a simple microfluidics system into a miniature ninety-six sample plate, allowing the user to carry out an immunological assay without a laboratory. Assay reagents are delivered into the assay plate without the need for separate devices commonly used in immunoassays. The ELISA-LOC was constructed using Laminated Object Manufacturing (LOM) technology to assemble six layers with an acrylic (poly(methyl methacrylate) (PMMA)) core and five polycarbonate layers micromachined by a CO(2) laser. The ELISA-LOC has three main functional elements: reagent loading fluidics, assay and detection wells, and reagent removal fluidics, a simple "surface tension" valve used to control the flow. To enhance assay sensitivity and to perform the assay without a lab, ELISA-LOC detection combines several biosensing elements: (1) carbon nanotube (CNT) technology to enhance primary antibody immobilization, (2) sensitive ECL (electrochemiluminescence) detection, and (3) a charge-coupled device (CCD) detector for measuring the light signal generated by ECL. Using a sandwich ELISA assay, the system detected SEB at concentrations as low as 0.1 ng ml(-1), which is similar to the reported sensitivity of conventional ELISA. The fluidics system can be operated by a syringe and does not require power for operation. This simple point-of-care (POC) system is useful for carrying out various immunological assays and other complex medical assays without a laboratory.
Airway Injuries after One-lung Ventilation: A Comparison between Double-lumen Tube and Endobronchial Blocker (2006)

Clinicians should be aware of an increased incidence of minor airway injuries that may impair patient satisfaction when using a double-lumen tube instead of an endobronchial blocker for one-lung ventilation.
Transient simulation of frequency-dependent nonuniform coupled lossy transmission lines (1994)

In this paper, we present an efficient method of simulating the transient response of frequency-dependent nonuniform lossy coupled transmission lines, which are terminated in active nonlinear loads. The transient simulation is carried out by applying the recursive convolution integration with impulse response functions derived from the orthogonal expansions of the transmission-line characteristic impedance and wave propagation functions in both time and spatial domains. Transient responses of nonuniform coupled transmission lines with skin-effect parameters are simulated for illustrations. The accuracy and efficiency of the discrete-time analysis are substantiated with exact analytical solutions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Piecewise linear two‐dimensional warping (2001)

Abstract As a novel elastic image matching technique, piecewise linear 2D warping (PL2DW) is investigated. In PL2DW, the mapping of each row of one image to another image is given by the linear interpolation of the mapping of several points, called pivots, prepared on the row. The linearization realizes a dynamic programming (DP)‐based algorithm with feasible computational complexity, although many DP‐based algorithms for elastic image matching are intractable. Experimental results show the effectiveness, and particularly the computational feasibility, of PL2DW. © 2001 Scripta Technica, Syst Comp Jpn, 32(12): 1–9, 2001
Serum Markers of Hepatocellular Carcinoma (2006)

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in some areas of the world with increasing incidence worldwide. Most of patients with HCC are diagnosed at a late stage. Therefore, the prognosis of HCC patients is generally very poor with a 5-year survival rate of less than 5%. Screening strategies including alpha-fetoprotein (AFP) and ultrasound every 6 months in patients with liver cirrhosis, the major risk factor for HCC development, have been recommended to detect HCC at earlier stages amenable to effective treatment strategies. AFP, however, is a marker with poor sensitivity and specificity and the ultrasound is highly dependent on the operator's experience. Apart from AFP, lens culinaris agglutinin-reactive AFP and des-gamma carboxyprothrombin and several other biomarkers (e.g., glypican-3, human hepatocyte growth factor, and insulin-like growth factor) have been proposed as markers for HCC detection. In addition, with recently employed techniques, such as gene-expressing microarrays and proteomics, it is to be expected that new HCC-specific markers will become available in the near future. For all such proposed markers, however, the clinical usefulness has to be carefully evaluated and validated.
Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications (2016)

We have recently described manufacturing of human induced pluripotent stem cells (iPSC) master cell banks (MCB) generated by a clinically compliant process using cord blood as a starting material (Baghbaderani et al. in Stem Cell Reports, 5(4), 647-659, 2015). In this manuscript, we describe the detailed characterization of the two iPSC clones generated using this process, including whole genome sequencing (WGS), microarray, and comparative genomic hybridization (aCGH) single nucleotide polymorphism (SNP) analysis. We compare their profiles with a proposed calibration material and with a reporter subclone and lines made by a similar process from different donors. We believe that iPSCs are likely to be used to make multiple clinical products. We further believe that the lines used as input material will be used at different sites and, given their immortal status, will be used for many years or even decades. Therefore, it will be important to develop assays to monitor the state of the cells and their drift in culture. We suggest that a detailed characterization of the initial status of the cells, a comparison with some calibration material and the development of reporter sublcones will help determine which set of tests will be most useful in monitoring the cells and establishing criteria for discarding a line.
Directing the Attention of a Wearable Camera by Pointing Gestures (2006)

Wearable visual sensors provide views of the environment which are rich in information about the wearer's location, interactions and intentions. In the wearable domain, hand gesture recognition is the natural replacement for keyboard input. We describe a framework combining a coarse-to-fine method for shape detection and a 3D tracking method that can identify pointing gestures and estimate their direction. The low computational complexity of both methods allows a real-time implementation that is applied to estimate the user's focus of attention and to control fast redirections of gaze of a wearable active camera. Experiments have demonstrated a level of robustness of this system in long and noisy image sequences. © 2006 IEEE.
Mild cognitive impairment: transition between aging and Alzheimer's disease. (2000)

The concept of the boundary between normal aging and early Alzheimer's disease is a focus of a great deal of research in the field of aging and dementia. Presumably there is a continuum of function between normality and the earliest signs of Alzheimer's disease. This transitional condition has been labeled mild cognitive impairment. Mild cognitive impairment refers to individuals who have a memory impairment greater than what one would expect for age, yet general cognitive function is preserved. Similarly activities of daily living are normal. However, the memory function of these individuals is abnormal for age and education. These subjects do not meet criteria for Alzheimer's disease. When mild cognitive impairment subjects are followed longitudinally, they tend to convert to clinically probable Alzheimer's disease as a rate of 10-15% per year. This is in contrast to normal elderly subjects who will develop Alzheimer's disease at a rate of 1-2% per year. Certain predictor variables are available to determine which subjects are more likely to progress at a rapid rate. Mild cognitive impairment is an important topic for research in aging and dementia and has also become the subject of several multicenter treatment trials.
What to do about bad language on the internet (2013)

The rise of social media has brought computational linguistics in ever-closer contact with bad language: text that defies our expectations about vocabulary, spelling, and syntax. This paper surveys the landscape of bad language, and offers a critical review of the NLP community’s response, which has largely followed two paths: normalization and domain adaptation. Each approach is evaluated in the context of theoretical and empirical work on computer-mediated communication. In addition, the paper presents a quantitative analysis of the lexical diversity of social media text, and its relationship to other corpora. 1