gebhart/patrepeval huggingface dataset:
Towards Personalized and Semantic Retrieval: An End-to-End Solution for E-commerce Search via Embedding Learning (2020)

Nowadays e-commerce search has become an integral part of many people's shopping routines. Two critical challenges stay in today's e-commerce search: how to retrieve items that are semantically relevant but not exact matching to query terms, and how to retrieve items that are more personalized to different users for the same search query. In this paper, we present a novel approach called DPSR, which stands for Deep Personalized and Semantic Retrieval, to tackle this problem. Explicitly, we share our design decisions on how to architect a retrieval system so as to serve industry-scale traffic efficiently and how to train a model so as to learn query and item semantics accurately. Based on offline evaluations and online A/B test with live traffics, we show that DPSR model outperforms existing models, and DPSR system can retrieve more personalized and semantically relevant items to significantly improve users' search experience by +1.29% conversion rate, especially for long tail queries by +10.03%. As a result, our DPSR system has been successfully deployed into JD.com's search production since 2019.
<title>Complex characterization of the Epson liquid crystal television</title> (1993)

The complex transmittance of an Epson liquid crystal television was determined, as a function of the video drive signal. Several different operating configurations of the LCTVs were established, and their usefulness as operating modes for spatial light modulators in the input- and-filter-planes of a hybrid correlator is discussed. A high-stability phase measurement scheme was developed to determine the operating curves, and this system is presented. The transient response of the liquid crystal television to field-rate changes in the video signal is also presented. It is observed that the switching speed of the liquid crystal molecules presents an obstacle to the operating speed of these devices.
Physiology-Driven Adaptive Virtual Reality Stimulation for Prevention and Treatment of Stress Related Disorders (2010)

The significant proportion of severe psychological problems related to intensive stress in recent large peacekeeping operations underscores the importance of effective methods for strengthening the prevention and treatment of stress-related disorders. Adaptive control of virtual reality (VR) stimulation presented in this work, based on estimation of the person's emotional state from physiological signals, may enhance existing stress inoculation training (SIT). Physiology-driven adaptive VR stimulation can tailor the progress of stressful stimuli delivery to the physiological characteristics of each individual, which is indicated for improvement in stress resistance. Following an overview of physiology-driven adaptive VR stimulation, its major functional subsystems are described in more detail. A specific algorithm of stimuli delivery applicable to SIT is outlined.
Multifunctional millimeter wave radar sensor for vehicle applications (2002)

Important aspects in future automotive concepts are comfort, reduced energy consumption and particularly improved safety. To optimize these points a precise sensing of the vehicle parameters and the environmental conditions is necessary. For example the velocity of a vehicle, the tilt angle, the height above ground and especially for active distance control and for autonomous driving the road condition have to be known. Well suited to carry out these tasks are radar sensors in the millimeter wave range. However, separate sensors for each purpose are uneconomic. Thus the merging of such sensor types to one multifunctional sensor is needed. Therefore a millimeter wave radar system which is mounted at the bottom of a car was conceived to measure the mentioned values and to get information about the road condition.
Immunoprotection of Xenocytes in a Hollow Fiber Bioartificial Liver (1992)

A new, hollow fiber bioartificial liver (BAL) was tested in an anhepatic rabbit model to assess the hollow fiber membrane as an immunologic barrier. The extracorporeal BAL contained rat hepatocytes (xenocytes) entrapped in collagen gel inside the lumen of hollow fibers with 100 kd nominal molecular weight cut-off. Blood from the anhepatic rabbit flowed in the extracapillary compartment. After 4 h of BAL hemoperfusion, the hepatocyte gels were tested for evidence of rabbit immunoglobulin and complement. Samples of the gels were stained with fluorescein isothiocyanate (FITC)-labeled antibodies directed against rabbit IgM, rabbit IgG (Fc and F[ab]2), and rabbit complement (C3) and studied by immunofluorescence microscopy. Enzyme-linked immunosorbent assay and Western blotting were used, respectively, to quantify and identify proteins inside the BAL and in the rabbit blood. These studies suggest that very little rabbit IgG (primarily fragments of IgG) and no IgM or C3 crossed the hollow fibers during hemoperfusion. Rat albumin steadily accumulated in the rabbit blood during hemoperfusion, which indicated membrane permeability to molecules of that size and stable hepatocyte function by the BAL. The authors conclude that hollow fibers with 100 kd nominal molecular weight cut-off provide immunoprotection for xenocytes in an extracorporeal BAL.
Liquid-Assisted Excimer Laser Micromaching for Ablation Enhancement and Debris Reduction (2006)

Previous studies demonstrated that laser ablation under transparent liquid can result in ablation enhacement and particle removal from the surface. In this work, the liquid-assisted excimer laser ablation process is examined for polyethylene terephthalate (PET), polymethyl methacrylate (PMMA), Si, and alumina with emphasis on ablation enhacement, surface topography, and debris formation. In the case of PET and PMMA, the effect of liquid is analyzed both for thin water film and bulk water. As the ablation enhanement by liquid is already known for Si and alumina, the analysis focuses on surface topography and debris formation resulting from the liquid-assisted laser ablation process. A KrF excimer laser is utilized for ablationg the materials in the fluence range 1~10 J/cm 2 . The results show that application of liquid increases the ablation rate of PMMA while that of PET remains unchanged even in the liquid-assisted process. It is also revealed that the liquid can significantly improve the surface quality by reducing the debris deposition. However, the surface roughness is generally deteriorated in the liquid-assisted process. The surface toporaphy is found to be strongly dependent on the method of liquid application, i.e., thin film or bulk liquid.
Plasminogen activating capacity in gingival fluid from deteriorating and stable jreiodontal pockets (2002)

The plasminogen activating system plays an important role in tissue proteolysis in physiological as well as pathological processes. Earlier studies have shown high concentrations of the plasminogen activator t-PA as well as its inhibitor PAI-2 in gingival crevicular fluid (GCF). In addition, gingival inflammatory reactions have been related to increases in t-PA and PAI-2. In order to explore the potential role of the plasminogen activating system for the development of destructive periodontal disease, the aim of this study was to assess the balance of the activator t-PA to the inhibitor PAI-2 in GCF from patients, clinically defined to represent different periodontal conditions. The Progression Group consisted of 12 periodontitis patients with 1 or more sites having shown an increased pocket depth of > or = 3 mm during the last 2 years of maintenance care and with > or = 8 unchanged or improving sites during the period. The Non Progression Group consisted of patients who had shown a decreased or unchanged pocket depth of all sites during the last 3 years of maintenance care. Sampling of GCF was done with small disks of Millipore-filter, and t-PA and PAI-2 were analyzed with ELISAs. There was no difference in the t-PA/PAI-2 ratio between the two groups. However, an intra-individual comparison within the Progression Group showed a higher ratio at the deteriorating sites than at the stable sites. Even though no difference was found between the groups, the higher t-PA/PAI-2 ratio at the deteriorating sites in the Progression Group suggests an involvement of the plasminogen activating system in the proteolytic events leading to breakdown of the tooth supporting tissues.
Compact laparoscopic assistant robot using a bending mechanism (2007)

This paper presents the development of a compact laparoscopic assistant robot. The robot was designed to increase convenience and reduce possible interference with surgical staff by confining the majority of motions inside the abdomen. Its size was miniaturized as much as possible for convenient handling. A bending mechanism composed of several articulated joints was introduced to produce motions inside the abdomen. The proposed assistant robot can generate 3-DOF motion, including 2-DOF internal bending motion and 1-DOF external linear motion. Since the robot itself functions as a laparoscope, a small CCD camera module and a bundle of optical fibers were integrated as part of the system. For accurate control, mathematical modeling of the bending mechanism and a method of hysteresis compensation were introduced and implemented. For the control of the robot, a voice interface and a visual-servoing method were implemented. The performance of the developed system was tested through solo-surgery of in vivo porcine cholecystectomy. It was found that the views generated by the bending mechanism were sufficient throughout the surgery. Since the robot has functions comparable to the previously developed systems, while retaining its compactness, it is expected to be a useful device for human cholecystectomy.
Protein damage and death by radiation in <i>Escherichia coli</i> and <i>Deinococcus radiodurans</i> (2010)

Deinococcus radiodurans is among a small number of bacterial species that are extremely resistant to ionizing radiation, UV light, toxic chemicals, and desiccation. We measured proteome oxidation (i.e., protein carbonylation, PC) in D. radiodurans as well as in standard and evolved resistant strains of Escherichia coli exposed to ionizing radiation or UVC light and found a consistent correlation with cell killing. The unique quantitative relationship between incurred PC and cell death holds over the entire range of killing for all tested bacteria and for both lethal agents, meaning that both bacterial species are equally sensitive to PC. We show that the extraordinary robustness of D. radiodurans depends on efficient proteome protection (but not DNA protection) against constitutive and radiation-induced PC consisting of low molecular weight cytosolic compounds. Remarkably, experimental evolution of resistance to ionizing radiation in E. coli coevolves with protection against PC. The decline in biosynthetic efficacy of the cellular proteome, as measured by the loss of reproduction of undamaged bacteriophage lambda in irradiated standard and evolved ionizing radiation-resistant E. coli, correlates with radiation-induced oxidative damage to host cells and their sensitivity to ionizing radiation. This correlation suggests that cell death by radiation is caused primarily by oxidative damage with consequential loss of maintenance activities including DNA repair.
Activation of podocytes by mesangial-derived TNF-α: glomerulo-podocytic communication in IgA nephropathy (2008)

We have previously documented that human mesangial cell (HMC)-derived TNF-alpha is an important mediator involved in the glomerulo-tubular communication in the development of interstitial damage in IgA nephropathy (IgAN). With the strategic position of podocytes, we further examined the role of mesangial cells in the activation of podocytes in IgAN. There was no binding of IgA from patients with IgAN to podocytes. Podocytes cultured with IgA from patients with IgAN did not induce the release of growth factors or cytokines. Furthermore, podocytes did not express mRNA of known IgA receptors. In contrast, IgA-conditioned medium (IgA-HMC medium) prepared by culturing HMC with IgA from patients with IgAN for 48 h significantly increased the gene expression and protein synthesis of TNF-alpha by podocytes with a 17-fold concentration above that of IgA-HMC medium. The upregulation of TNF-alpha expression by podocyte was only abolished by a neutralizing antibody against TNF-alpha but not by other antibodies. Exogenous TNF-alpha upregulated the synthesis of TNF-alpha by podocytes in an autocrine fashion. IgA-HMC medium prepared with IgA from patients with IgAN also significantly upregulated the expression of both TNF-alpha receptor 1 and 2 in podocytes. Our in vitro finding suggests podocytes may play a contributory role in the development of interstitial damage in IgAN by amplifying the activation of tubular epithelial cells with enhanced TNF-alpha synthesis after inflammatory changes of HMC.
Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors. (1998)

Germ-line mutations in a serine/threonine kinase gene, LKB1, were recently shown to underlie Peutz-Jeghers syndrome (PJS), a hereditary disorder that predisposes to benign and malignant tumors of multiple organ systems. Most mutations that have been described thus far dramatically change the predicted protein and are likely to be of an inactivating nature. This observation and a previous observation that the LKB1 locus is often deleted in PJS polyps suggest that the gene may function as a tumor suppressor. We examined whether somatic mutations in this gene are present in sporadic carcinomas of the colon and testis, tumors that are characteristic of PJS. First, 20 randomly selected colorectal and 28 testicular tumors were analyzed by single-strand conformation polymorphism analysis. No mutations in LKB1 were found in colorectal tumors. One testicular tumor displayed a heterozygous missense type variant, in which glycine 163 was changed to aspartic acid. This change was absent in the DNA of normal tissue. To better focus our efforts, we tested 75 additional colon carcinomas for loss of heterozygosity at 19p, where LKB1 is localized. Of 75 samples analyzed, 50 were informative with a closely linked marker, D19S886, and 13 (26%) of these displayed loss of heterozygosity. The 13 tumors were scrutinized for LKB1 mutations by genomic sequencing. This analysis revealed no changes. Together, these findings suggest that somatic mutations of LKB1 are not frequent in colorectal and testicular cancer.
Learning a discriminative classifier using shape context distances (2003)

For the purpose of object recognition, we learn one discriminative classifier based on one prototype, using shape context distances as the feature vector. From multiple prototypes, the outputs of the classifiers are combined using the method called "error correcting output codes". The overall classifier is tested on a benchmark dataset and is shown to outperform existing methods with far fewer prototypes.
Breaking and provably repairing the SSH authenticated encryption scheme (2004)

The secure shell (SSH) protocol is one of the most popular cryptographic protocols on the Internet. Unfortunately, the current SSH authenticated encryption mechanism is insecure. In this paper, we propose several fixes to the SSH protocol and, using techniques from modern cryptography, we prove that our modified versions of SSH meet strong new chosen-ciphertext privacy and integrity requirements. Furthermore, our proposed fixes will require relatively little modification to the SSH protocol and to SSH implementations. We believe that our new notions of privacy and integrity for encryption schemes with stateful decryption algorithms will be of independent interest.
Freeze-TCP: a true end-to-end TCP enhancement mechanism for mobile environments (2002)

Optimizing TCP (transport layer) for mobility has been researched extensively. We present a brief summary of existing results which indicates that most schemes require intermediaries (such as base stations) to monitor the TCP traffic and actively participate in flow control in order to enhance performance. Although these methods simulate end-to-end semantics, they do not comprise true end-to-end signaling. As a result, these techniques are not applicable when the IP payload is encrypted. For instance IPSEC, which is expected to be standard under IPv6, encrypts the entire IP payload making it impossible for intermediaries to monitor TCP traffic unless those entities are part of the security association. In addition, these schemes require changes (in the TCP/IP code) at intermediate nodes making it difficult for the mobile clients to inter-operate with the existing infrastructure. In this paper we explore the "freeze-TCP" mechanism which is a true end-to-end scheme and does not require the involvement of any intermediaries (such as base stations) for flow control. Furthermore, this scheme does not require any changes on the "sender side" or intermediate routers; changes in TCP code are restricted to the mobile client side, making it possible to fully inter-operate with the existing infrastructure. We then outline a method which integrates the best attributes of freeze-TCP and some existing solutions. Performance results highlight the importance of pro-active action/signaling by the mobile-host. The data indicate that in most cases, simply reacting to disconnections tends to yield lower performance than pro-active mechanisms such as freeze-TCP.
Field bioassays of permethrin-treated uniforms and a new extended duration repellent against mosquitoes in Pakistan. (1988)

Field bioassays were conducted to evaluate the effectiveness of different treatment combinations of permethrin-impregnated clothing and a new extended duration repellent formulation of deet against natural populations of mosquitoes in Islamabad, Pakistan. Tests were initiated 2-2 1/2 hours prior to sunset and volunteers who wore the topical repellent applied it 8 hours earlier. The most effective treatment was a combination of wearing both the permethrin-impregnated clothing and the repellent on exposed skin. This combination provided 100% protection from bites whereas volunteers wearing only treated clothing received 57% protection. Those wearing only repellent received 89% protection, but, under the biting pressure observed, this was not significantly different from the treated clothing-repellent combination.
Bayesian Classifier with Simplified Learning Phase for Detecting Microcalcifications in Digital Mammograms (2009)

Detection of clustered microcalcifications (MCs) in mammograms represents a significant step towards successful detection of breast cancer since their existence is one of the early signs of cancer. In this paper, a new framework that integrates Bayesian classifier and a pattern synthesizing scheme for detecting microcalcification clusters is proposed. This proposed work extracts textural, spectral, and statistical features of each input mammogram and generates models of real MCs to be used as training samples through a simplified learning phase of the Bayesian classifier. Followed by an estimation of the classifier's decision function parameters, a mammogram is segmented into the identified targets (MCs) against background (healthy tissue). The proposed algorithm has been tested using 23 mammograms from the mini-MIAS database. Experimental results achieved MCs detection with average true positive (sensitivity) and false positive (specificity) of 91.3% and 98.6%, respectively. Results also indicate that the modeling of the real MCs plays a significant role in the performance of the classifier and thus should be given further investigation.
Studies on the Protein-Protein and Protein-Ligand Interactions Involved in Retinol Transport in Plasma (1970)

Abstract Studies were conducted to examine the chemical and physical properties of human plasma retinol-binding protein (RBP) and prealbumin (PA), and the factors affecting their interaction with each other and with the ligands retinol and thyroxine, respectively. The effects of changes in temperature, pH, and urea concentration and the effects of reduction and alkylation of disulfide bonds and of iodination were assessed. Analytical ultracentrifuge studies established the formation of a 1:1 molar complex between the two proteins. The estimated molecular weight of the complex (approximately 70,000) was almost exactly the sum of the molecular weights of the individual proteins (PA, approximately 49,000 and RBP, 21,000). The complex was stable in the temperature range 4–42.5° and in the pH range 5.8 to 7.5. Considerable dissociation of the complex occurred as the pH was raised from 8.6 to 10.3. Addition of 6 m urea completely disrupted the RBP-PA complex, markedly reduced the affinity of PA for thyroxine, but did not interfere with the association of retinol with RBP. Only one of the two disulfide bonds of PA was readily accessible to reduction and alkylation. Reduction of this one disulfide bond did not affect the binding of either RBP or thyroxine to PA. In contrast, both disulfide bonds of RBP were highly resistant to reduction. When the disulfide bonds of RBP were reduced and alkylated, however, the retinol-RBP complex was disrupted, and retinol was completely lost from the protein. Iodination of RBP up to the level of 4.3 atoms of iodine per molecule selectively interfered with the interaction of RBP with PA, without disrupting the retinol-RBP complex. These studies demonstrate that it is possible to affect selectively the different interactions involved in the RBP-PA system responsible for retinol transport in plasma.
Identification of Differentially Expressed cDNA Clones from Gerbil Cochlear Outer Hair Cells (2002)

In order to identify genes that are associated with outer hair cell(OHC)-specific function, a plasmid library enriched with OHC-specific gene products was constructed using single cell-type-specific complementary DNA (cDNA) and a PCR subtractive hybridization strategy. As a first step, we created separate OHC and inner hair cell (IHC) cDNA pools from individually collected cells using a nonspecific reverse transcription polymerase chain reaction. Next, the OHC cDNA was subtracted against IHC cDNA using a PCR-based subtractive technique. IHCs and OHCs share many common features, making IHC cDNA an ideal 'driver' to 'subtract away' common hair cell gene products and enrich differentially expressed cDNAs, including OHC-specific genes. The subtracted OHC cDNAs were then cloned to generate an OHC - IHC subtracted cDNA plasmid library. Finally, a differential screening procedure was performed, resulting in 477 differentially positive clones. After analysis of these 477 clones, 50 known genes were identified, including two previously known OHC-specific proteins: oncomodulin and the recently described motor protein prestin. An additional 84 novel clones were also found. As this library of cDNA fragments represents differentially expressed genes in OHCs, it can be used as starting material for isolation and characterization of a complete set of OHC gene products, an important step in investigating normal and abnormal cochlear function.