gebhart/patrepeval huggingface dataset:
Technology Infusion in A Chinese Middle School: A Comparative Perspective (2000)

This paper reports on an investigation of technology infusion at QiBao Middle School, one of the leading secondary schools in Shanghai (China). Major focuses of the study are models of professional development for teachers and how teachers enlist the help of their students. Results are presented related to: technology infrastructure; technology competence and training for faculty and staff; technology expectations and activities for students; the QiBao Research Association for Modern Educational Technology; the impact of technology in QiBao; and multimedia courseware contests. It is concluded that the Chinese experience may have relevance for American schools; while China started well behind American schools in access to and use of information technology, it has rapidly been able to mobilize and train teachers to infuse technology. (MES) Reproductions supplied by EDRS are the best that can be made from the original document. Technology Infusion in A Chinese Middle School: A Comparative Perspective PERMISSION TO REPRODUCE AND DISSEMINATE THIS MATERIAL HAS BEEN GRANTED BY
Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease (1996)

Neonatal gnotobiotic pigs orally inoculated with virulent (intestinal-suspension) Wa strain human rotavirus (which mimics human natural infection) developed diarrhea, and most pigs which recovered (87% protection rate) were immune to disease upon homologous virulent virus challenge at postinoculation day (PID) 21. Pigs inoculated with cell culture-attenuated Wa rotavirus (which mimics live oral vaccines) developed subclinical infections and seroconverted but were only partially protected against challenge (33% protection rate). Isotype-specific antibody-secreting cells (ASC were enumerated at selected PID in intestinal (duodenal and ileal lamina propria and mesenteric lymph node [MLN]) and systemic (spleen and blood) lymphoid tissues by using enzyme-linked immunospot assays. At challenge (PID 21), the numbers of virus-specific immunoglobulin A (IgA) ASC, but not IgG ASC, in intestines and blood were significantly greater in virulent-Wa rotavirus-inoculated pigs than in attenuated-Wa rotavirus-inoculated pigs and were correlated (correlation coefficients: for duodenum and ileum, 0.9; for MLN, 0.8; for blood, 0.6) with the degree of protection induced. After challenge, the numbers of IgA and IgG virus-specific ASC and serum-neutralizing antibodies increased significantly in the attenuated-Wa rotavirus-inoculated pigs but not in the virulent-Wa rotavirus-inoculated pigs (except in the spleen and except for IgA ASC in the duodenum). The transient appearance of IgA ASC in the blood mirrored the IgA ASC responses in the gut, albeit at a lower level, suggesting that IgA ASC in the blood of humans could serve as an indicator for IgA ASC responses in the intestine after rotavirus infection. To our knowledge, this is the first report to study and identify intestinal IgA ASC as a correlate of protective active immunity in an animal model of human-rotavirus-induced disease.
Hardware Aspects of Montgomery Modular Multiplication (2017)

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Enrichment, Isolation, and Emended Description of Pedomicrobium ferrugineum Aristovskaya and Pedomicrobium manganicum Aristovskaya (1981)

In 1961 Aristovskaya described the new hyphal budding bacteria Pedomicrobium ferrugineum and Pedomicrobium manganicum. Only a limited amount of information concerning these bacteria was obtained from enrichment cultures, and these cultures no longer exist. In an effort to revive investigations on pedomicrobia, six new iron-depositing strains were isolated from podzolic soils. One of these isolates, strain S-1290 (=ATCC 33119 =DSM 1540), was investigated thoroughly and is cited in the Approved Lists of Bacterial Names as the type strain of P. ferrugineum. Four other isolates (strains P-1196, Q-1197, R-1198, and T-1130) showed sufficient similarity to strain S-1290 to be placed in the same species. The taxonomic position of the sixth isolate, strain F-1225, is not yet certain. One additional isolate, strain E-1129 (=ATCC 33121 =DSM 1545), which deposits manganese, was isolated from a quartzite rock pool. This isolate closely resembles the original description of P. manganicum and is cited in the Approved Lists as the type strain of this species. I present an emended description of the genus Pedomicrobium and compare the generic properties of Pedomicrobium with those of other hyphal budding bacteria. To encourage further work on pedomicrobia, I also describe enrichment and isolation procedures for these bacteria. Cultures of all of the new strains are available from the American Type Culture Collection and from the Deutsche Sammlung von Mikroorganismen.
FIBRE LASERS AND AMPLIFIERS FOR TELECOMMUNICATIONS (1987)

Optical amplifiers and signal sources in fibre form should share the same characteristics of low loss, good power confinement and equivalent geometry as single-mode fibre used in telecommunications. Recent work(1,2) has shown that silica-based single-mode fibres may be doped with rare-earth ions, allowing moderate concentrations to be deposited in the GeO2 - SiO2 matrix. These dopants absorb pump radiation at characteristic wavelengths in the visible to near-IR regions and produce strong fluorescent emmissions in wavelength regions of high fibre transparency(3). Optically-pumped optical amplifiers can be made, and with suitable feedback lasing can be achieved in useful wavelength regions.
Tips on tactics – a legal perspective on innovating beyond the corporate boundary (2002)

The legal framework for extending innovation beyond the corporate boundary is the Strategic Alliance (or partnership) Agreement. Before entering into any type of alliance involving a joint development arrangement, every company whose core assets are comprised of intellectual property should conduct an internal Intellectual Property Audit. Make certain what you own (or control through licenses) it may be more or less than you think. The second phase of the Intellectual Property Audit is to make sure your Intellectual Property Assets are protected. Begin drafting the Alliance Agreement by articulating the goals of the alliance as specifically as possible. Define the product to be developed or area to be explored in detail. The Alliance Agreement should define the what technology is proprietary to each party. Determine in advance who collects the money, how is the money split, and who does the accounting. Each party should be individually responsible for the cost of defending any claims of infringement. Options can be tied to the development and testing milestones that allow you to get out of the deal entirely or reduce it from an exclusive to a non‐exclusive arrangement.
Severe traumatic brain injury in Switzerland - feasibility and first results of a cohort study (2008)

Severe TBI was associated with high case fatality and considerable morbidity in survivors. We demonstrated the feasibility of a multicentre cohort study in Switzerland with the aim of identifying modifiable determinants of outcome and improving current trauma care.
Current Awareness (2007)

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Saul Alinsky in Retrospect (1984)

Alinsky was the best known and most controversial community organizer in the country -he was also a pioneer clinical sociologist, as shown by the preceding articles on his career as a criminologist and a community organizer.I became acquainted with the Alinsky family in the 1950s as a teenager in Chicago.A youth group I belonged to sometimes met at the Alinsky's South Side home on Woodlawn Avenue in Kenwood, a couple of miles from the community where Alinsky's The Woodlawn Organization (TWO) took on City Hall and the University of Chicago.The last time I saw him was in the spring of 1966 at a seminar I had organized for him at UCLA, where I was a graduate student in sociology.Alinsky was a charismatic figure, portly, with a deep and commanding voice, who could display both brilliant wit and biting sarcasm.He was a lightning rod for controversy.Yet, under his gruff exterior there was a deeply compassionate man who genuinely liked people from all walks of life.
Hardware based neural network data fusion for classification of Earth surface conditions (2003)

A hardware-based neural network data fusion system is used for fast and accurate classification of surface conditions, based on SSMI satellite measurements. The system processes sensory data in three consecutive phases: (1) preprocessing to extract feature vectors and enhance separability among detected classes; (2) preliminary classification of Earth surface patterns at two separate and parallel acting classifiers, the backpropagation neural network (BP ANN) and the binary decision tree (BDT) classifiers, and (3) data fusion of results from preliminary classifiers to obtain the optimal performance in overall classification. Both the BDT classifier and fusion centers are implemented by neural networks. This system is implemented in a prototype of a massively parallel and dynamically reconfigurable modular neural ring coprocessor. It increases the detection accuracy to 94% compared with 88% for BP ANN and 80% for BDT classifiers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A New Adaptive Filter Algorithm for System Identification using Independent Component Analysis (2007)

This paper proposes a new adaptive filter algorithm for system identification using independent component analysis (ICA), which separates the signal from noisy observation under the assumption that the signal and noise are independent. We first introduce an augmented state-space expression of the observed signal, representing the problem in terms of ICA, and then use an adaptive gradient descent algorithm to separate the noise from the signal. A local convergence condition is also shown. The proposed algorithm can be applied to the acoustic echo cancellation problem directly and some simulations have been carried out to illustrate its effectiveness.
Synthesis of 1‐Aryl‐3‐oxo‐1,2,3,4‐tetrahydrobenzo[f]quinolines. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Electronic Structure of Impurities in Ferromagnetic Iron. III. Light Interstitials (1987)

A self-consistent calculation of the electronic structure of light impurities (µ + , H, He, …, F, Ne) at substitutional and interstitial sites in ferromagnetic iron is presented. The calculation is based on the KKR method with the impurity potential self-consistently determined by use of the local spin density functional formalism. The adiabatic potential of impurity around the center of a substitutional site is also calculated within the same framework with the result that it takes a maximum value at the center in the cases of µ + , H, B, C, N, O and F, a minimum one in the cases of He, Li and Ne and is quite flat in the case of Be. A qualitative argument is given on the mechanism underlying the variation of the adiabatic potential with atomic number. Experimental data on the hyperfine interaction of impurity nuclei are discussed in the light of these calculations to conclude plausible locations of impurities.
Selenoprotein P. Its Structure and Functions. (2000)

Selenoprotein P (SeP : the "P" denotes its presence in plasma) is the major selenoprotein in plasma. All selenoproteins so far reported contain one atom of selenium (Se) as selenocysteine per molecule except SeP, which is thought to contain ten atoms of Se as selenocysteine per molecule. SeP contains 50% of the total Se in plasma. The function of Sep is currently unknown, although several indirect lines of evidence suggest that SeP is a free radical scavenger or Se transporter. Recently, we reported that SeP is capable of reducing phospholipid hydroperoxide in the presence of glutathione, and characterized the enzymatic nature of SeP. SeP is also reported to function as a peroxynitrite scavenger or cell survival factor in primary culture of neurons. In this minireview, we discuss the relationship between the structure and function of SeP.
Neonatal methamphetamine administration induces region‐specific long‐term neuronal morphological changes in the rat hippocampus, nucleus accumbens and parietal cortex (2004)

Previous studies have demonstrated that rats exposed to methamphetamine (MA) during the neonatal period display deficits in spatial learning and memory. The underlying correlates are unknown; therefore, this study was devised to determine whether neuronal changes occur in the dentate gyrus (DG), nucleus accumbens (NAcc) and cortex of adult rats exposed to 10 mg/kg MA administered four times daily from P11-20 using Golgi-Cox staining [Gibb, R. & Kolb, B. (1998) J. Neurosci. Meth., 79, 1-4]. The DG and NAcc demonstrated a decrease in the number of spines per neuron and the NAcc showed an associated decrease in dendritic length. Selective changes in cortex were observed because increased dendritic length in the parietal cortex occurred with no change in the number of spines, and no differences were noted for either dendritic length or spines in the medial frontal cortex. The data suggest a potential cause for the learning and memory deficits induced by neonatal MA exposure; however, the underlying mechanism that produces these neuronal changes is unknown.
Differential modulation of P-glycoprotein transport by protein kinase inhibition (1993)

Previous studies of P-glycoprotein have demonstrated that its function can be modulated by phosphorylation. In the present study, inhibition of protein kinase C with calphostin C or stauroporine or prolonged treatment with the phorbol ester TPA decreased phosphorylation of P-glycoprotein, and impaired transport of vinblastine. Calphostin C also inhibited transport of actinomycin D, vincristine, rhodamine, and azidopine in SW620 Ad300 multidrug-resistant human colon carcinoma cells. Photoaffinity labeling of P-glycoprotein with azidopine was decreased by calphostin C, suggesting that dephosphorylation alters the affinity of P-glycoprotein for its substrates. Impaired transport of rhodamine in normal T lymphocytes treated with staurosporine demonstrates that modulation of P-glycoprotein function is not limited to cells selected for drug resistance in vitro. Transport of P-glycoprotein antagonists in SW620 Ad300 cells was also affected by calphostin C. Cyclosporin A transport decreased, while verapamil transport increased. Cyclosporin A in calphostin C-treated cells resulted in additive P-glycoprotein antagonism, while no additive effect could be demonstrated with verapamil, suggesting that the increase in verapamil transport makes it a poorer P-glycoprotein antagonist. These studies suggest that transport by P-glycoprotein is a dynamic process which can be modulated by phosphorylation, and that antagonists may block P-glycoprotein differently in different phosphorylation states.
Effects of Hot-Working Processes and Impurities on the Properties of Cold-Drawn Cu Wires (1987)

The softening characteristics of cold-drawn pure copper wires were studied in relation to hot-working processes and impurities of hot worked Cu wire rods. The characteristics of several kinds of hot-rolled wire rods were examined by means of structural observations, tensile tests and electrical resistivity measurements. The softening characteristics of cold-drawn copper wires were obtained from spring elongation tests and electrical resistivity measurements of 90% cold-drawn wires.It was found that the grain size and Cu2O particle size of the continuous casting and rolling rod (SCR: Southwire Continuous Rod) were the smallest and its Cu2O particle distribution was uniform. On the other hand, the grain size of Oxygen Free Copper (OFC) wire rod was the largest and its electrical conductivity was the highest. SCR cold-drawn copper had the lowest softening temperature. Specimens of copper wires could be arranged according to the order of softening tendencies by annealing:\ oindentSCR>TPC 1(normal Tough Pitch Copper)>OFC>TPC 3(Tough Pitch Copper with 16 ppm Pb and 11 ppm Sn).\ oindentA large amount of annealing twins was observed in the SCR wires.From these experimental results, the softening characteristics of the cold-drawn copper wires are considered to be related to metallurgical structure which depends on the hot-working processes and purities.
Phosphorylation Does Not Prompt, Nor Prevent, the Formation of  -synuclein Toxic Species in a Rat Model of Parkinson's Disease (2008)

Phosphorylation is involved in numerous neurodegenerative diseases. In particular, alpha-synuclein is extensively phosphorylated in aggregates in patients suffering from synucleinopathies. However, the share of this modification in the events that lead to the conversion of alpha-synuclein to aggregated toxic species needed to be clarified. The rat model that we developed through rAAV2/6-mediated expression of alpha-synuclein demonstrates a correlation between neurodegeneration and formation of small filamentous alpha-synuclein aggregates. A mutation preventing phosphorylation (S129A) significantly increases alpha-synuclein toxicity and leads to enhanced formation of beta-sheet-rich, proteinase K-resistant aggregates, increased affinity for intracellular membranes, a disarrayed network of neurofilaments and enhanced alpha-synuclein nuclear localization. The expression of a mutation mimicking phosphorylation (S129D) does not lead to dopaminergic cell loss. Nevertheless, fewer but larger aggregates are formed, and signals of apoptosis are also activated in rats expressing the phosphorylation-mimicking form of alpha-synuclein. These observations strongly suggest that phosphorylation does not play an active role in the accumulation of cytotoxic pre-inclusion aggregates. Unexpectedly, the study also demonstrates that constitutive expression of phosphorylation-mimicking forms of alpha-synuclein does not protect from neurodegeneration. The role of phosphorylation at Serine 129 in the early phase of Parkinson's disease is examined, which brings new perspective to therapeutic approaches focusing on the modulation of kinases/phosphatases activity to control alpha-synuclein toxicity.
Xylene: An overview of its health hazards and preventive measures (2010)

Xylene is an aromatic hydrocarbon known for its wide usage in tissue processing, staining and cover slipping in the histology laboratory. The hazards of xylene are well documented, making it a potential occupational hazard for the histopathological technicians. As every other profession became cautious of the occupational hazards, the very speciality that identifies the illnesses became one of the last to become aware and remedy its own hazards. This review article aims to discuss the toxicity of xylene and safety measures to counteract the hazards and enlists the pros and cons of using various substitutes that claim to be much safer, better and faster.
Reversible Photocontrol of Peptide Conformation with a Rhodopsin-like Photoswitch (2012)

Reversible photocontrol of biomolecules requires chromophores that can efficiently undergo large conformational changes upon exposure to wavelengths of light that are compatible with living systems. We designed a benzylidene-pyrroline chromophore that mimics the Schiff base of rhodopsin and can be used to introduce light-switchable intramolecular cross-links in peptides and proteins. This new class of photoswitch undergoes an ~10 Å change in end-to-end distance upon isomerization and can be used to control the conformation of a target peptide efficiently and reversibly using, alternately, violet (400 nm) and blue (446 nm) light.
A highly active K-Co-Mo/C catalyst for mixed alcohol synthesis from CO + H2 (2003)

A highly homogeneous and dispersed K-Co-Mo/C catalyst which prepared by a sol-gel method exhibits high alcohol yield, especially high C2+ OH selectivity for mixed alcohol synthesis from CO + H2.
Evaluating Factors of CRM on Customer Satisfaction - Managerial Perspective of PTCL (Telecommunication Giant of Pakistan) (2014)

The aim of the study is to evaluate the factors of Customer Relationship Management on Customer Satisfaction from the managerial perspective of PTCL employees (CRM users) to check the CRM is increasing customer satisfaction through this study. The research is quantitative bases in which the research is conducted through primary data received from questionnaire from the respondents of PTCL managerial level. Total population is included in the research since it was small population. Total 78 populations is forwarded online survey out of which 60 respondents submitted the questionnaire and research is the results of 60 respondents receive. The research is limited to Karachi bases due to having term paper report and it is also limited to respondent CRM users only and managerial level is only BPS – 17 and above is called managerial level as per definition of PTCL employees. The research finds that the customer satisfaction is increasing due to CRM factors of focusing key customers, organize around CRM, managing knowledge and incorporating CRM technology and results are contributing positively to this study where majority of CRM users and managerial level have either remarked with strongly agree and agree which is showing mean greater than 3.0. The study is followed by the research which is already conducted earlier and past research shows that it can further be extended for evaluating sales growth and customer retention.
Growth and differentiation of conducting airway epithelial cells in culture (1997)

The development of routine techniques for the isolation and in vitro maintenance of conducting airway epithelial cells in a differentiated state provides an ideal model to study the factors involved in the regulation of the expression of mucociliary differentiation. Several key factors and conditions have been identified. These factors and conditions include the use of biphasic culture technique to achieve mucociliary differentiation, the use of such stimulators as the thickness of collagen gel substratum, the calcium level, and vitamin A, and such inhibitors as the growth factors, epidermal growth factor and insulin, and steroid hormones, for mucous cell differentiation. Using the defined culture medium, the life cycle of the mucous cell population in vitro has been investigated. It was demonstrated that the majority of the mucous cell population in primary cultures is not involved in the replication of deoxyribonucleic acid (DNA). However, the mucous cell type is capable of self-renewal in culture, and this reproduction is vitamin A dependent. Furthermore, differentiation from nonmucous to mucous cell type can be demonstrated by adding back a positive regulator such as vitamin A to the "starved" culture. Cell kinetics data suggest that vitamin A-dependent mucous cell differentiation in culture is a DNA replication-independent process, and the process is inhibited by transforming growth factor-beta1.
The microflora of the mud deposits of Lake Mendota [Wisconsin] (1935)

This paper presents bacteriological analyses of the deposits of Lake Mendota, a fresh-water lake in Wisconsin. Samples were taken from two different stations in both winter and summer from the surface of the deposit and from the underlying marl. A varied flora was found, including most of the groups of soil microorganisms. The nitrifying and cellulose decomposing bacteria were detected only in a few instances in the surface muds.