gebhart/patrepeval huggingface dataset:
A Mouse Homologue of the Xenopus Germ Cell-Specific Ribonucleic Acid/Deoxyribonucleic Acid-Binding Proteins p54/p56 Interacts with the Protamine 2 Promoter1 (1995)

Recent evidence indicates that a member of the Y box-binding family of transcriptional regulators is identical to p56, a predominant protein of messenger ribonucleoprotein complexes. The p56 protein is highly enriched in oocytes and testis, and a functional RNA binding mouse cytoplasmic homologue has been cloned and partially characterized. Because few potential testis-specific transcriptional regulators have been identified, the testis-enriched Y box-binding proteins represent trans-acting elements of a unique model system for the study of haploid gene expression. The 5' flanking region of the testis-specific, haploid-expressed mouse protamine 2 gene contains an element with a 9-of-12 nucleotide identity with the previously defined Y box consensus sequence. We have investigated the possible role of Y box-binding proteins in transcriptional regulation of protamine 2 using specific antibodies and DNA-protein binding assays. Western blot analyses with two different anti-p54/p56 antibodies demonstrate that a mouse homologue of Xenopus p54/p56 is present in transcriptionally active mouse testis nuclear extracts. Our results further indicate that the Xenopus Y box-binding proteins bind to an element 5' to the mouse protamine 2 gene. Similarly, binding of the mouse testis homologue to the protamine 2 Y box element is demonstrated by gel mobility shift and antibody supershift analyses. The demonstrated interactions between testis-enriched Y box-binding proteins and protamine 2 transcriptional control elements therefore represent a unique system for functional studies to determine the mechanism of regulation of haploid gene expression.
A highly active, stable and synergistic Pt nanoparticles/Mo2C nanotube catalyst for methanol electro-oxidation (2015)

Poor electrocatalytic activity and carbon monoxide (CO) poisoning of the anode in Pt-based catalysts are still two major challenges facing direct methanol fuel cells. Herein, we demonstrate a highly active and stable Pt nanoparticle/Mo2C nanotube catalyst for methanol electro-oxidation. Pt nanoparticles were deposited on Mo2C nanotubes using a controllable atomic layer deposition (ALD) technique. This catalyst showed much higher catalytic activity for methanol oxidation and superior CO tolerance, when compared with those of the conventional Pt/C and PtRu/C catalysts. The experimental evidence from X-ray absorption near-edge structure spectroscopy and scanning transmission X-ray microscopy clearly support a strong chemical interaction between the Pt nanoparticles and Mo2C nanotubes. Our studies show that the existence of Mo2C not only minimizes the required Pt usage but also significantly enhances CO tolerance and thus improves their durability. These results provide a promising strategy for the design of highly active next-generation catalysts. Platinum nanoparticles on Mo2C nanotubesact as a stable, highly active catalyst for methanol electro-oxidation, find a binational team led by Chunwen Sun from Institute of Physics, Chinese Academy of Sciences. Methanol electro-oxidation is a critical reaction in direct methanol fuel cells, but conventional methods for catalysing it using Pt-based catalysts loaded on carbon suffer from low activities and CO poisoning of the anode. Now, researchers in China and Canada have discovered that a catalyst produced by depositing Pt nanoparticles on Mo2C nanotubes by controlled atomic layer deposition can overcome both problems. Based on X-ray spectroscopy and microscopy measurements, they attribute this to synergistic effects between the two components. Their results reveal that the presence of Mo2C both reduces the amount of Pt needed (thus lowering costs) and enhances CO tolerance (thereby improving durability), indicating that it is a promising strategy for designing highly active next-generation catalysts. In this paper, we demonstrate a highly active and stable Pt nanoparticle/Mo2C nanotube catalyst for methanol electro-oxidation. Well-dispersed Pt nanoparticles were deposited on Mo2C nanotubes using a controllable atomic layer deposition (ALD) technique. This catalyst showed much higher catalytic activity for methanol oxidation and superior CO tolerance, when compared with those of the conventional Pt/C and PtRu/C catalysts. These results provide a promising strategy for the design of highly active next-generation catalysts.
Constituents of Sindora sumatrana MIQ. I. Isolation and NMR Spectral Analysis of Sesquiterpenes from the Dried Pods. (1994)

Investigation of the neutral fraction of the dried pods of Sindora sumatrana MIQ. has resulted in the isolation of three new sesquiterpenoids (2, 6 and 8) together with nine known ones (1, 3, 4, 5, 7, 9, 10, 11a and 12a), of which three (7, 10 and 12a) are reported for the first time from a natural source. One other compound, 4-stigmasten-3-one (13) (together with a sterol mixture; β-sitosterol, stigmasterol and campesterol) was also obtained. The structures of all the isolated sesquiterpenes were determined by means of spectroscopic methods, mainly two-dimensional NMR techniques, and the compounds were found to have the caryophyllane, humulane, clovane and caryolane skeletons. The NMR data of the isolated sesquiterpenes are also discussed.
INDUCED DRAG AND WINGLETS (1996)

A simple method is described which allows consideration of the most significant higher order term in the calculation of the induced drag of nonplanar wings. This is the induced lift due to the velocities that the lifting vortices induce on themselves. This induced lift does not change the induced drag. It is positive for positive dihedral and winglets above the wing tip and negative for negative dihedral and winglets below the wing tip. Experiments with small models clearly demonstrate this difference which is neglected in the classical theory. This shows that the higher order effects should be taken into account. The results of several parameter variations are presented.
Effects of bone wax on bacterial clearance. (1981)

The hemostatic benefit of bone wax placed in cancellous bone occurs at the expense of the wax persisting at the bony site for years. As such, bone wax appears to act as a foreign body. This study examines the effect of bone wax on the ability of cancellous bone to clear bacteria. The iliac crest of rabbits was penetrated to a standard depth with an 18-gauge needle. Subsequently, nothing or Staphylococcus aureus, 10(5) colony-forming units, was innoculated in the needle site and followed by the subcortical placement of a cylinder of bone wax or similarly sized stainless steel rod. Ten days later, the site of bony penetration was excised and cultured. Eighty percent of animals whose bone was implanted with bacteria and bone wax together had positive cultures. Forty percent of animals whose bone was implanted with bacteria and a steel rod also had positive cultures. The difference between these groups (bacteria with bone wax or with steel rod) was not statistically significant. However, these combinations of bacteria with foreign body were significantly different from the bacteria only or bone wax only or steel rod only groups in which no positive cultures were observed. The data indicate that bone wax significantly impairs the ability of cancellous bone of rabbits to clear a standard inoculum of S. aureus. This effect appears to be the same as that observed with a different but similarly sized foreign body (steel rod).
Preparation of Li<sub>2</sub>O-SiOs<sub>2</sub> gels and glasses by sol-gel methods (1990)

Li<sub>2</sub>O—SiO<sub>2</sub> gels with lithia contents from 5 to 40 mol% have been prepared by several sol-gel methods. Silicon ethoxide and silicon methoxide have been used as starting silicon compounds while different lithium alkoxides and lithium salts were tried as lithium carriers. Drying Control Chemical Additives (DCCAs) were also used. The gelling behavior and the state of the gels are reported for the different routes of preparation. Monolithic gels could be obtained by the use of formamide as a DCCA but not with glycerol. Many samples were dried and annealed then to temperatures up to 600 °C. Onset and kind of crystallization were observed by x-ray diffraction. The structural development was investigated by <sup>29</sup>Si NMR. Li2O-SiO<sub>2</sub> gel glasses crystallize much more easily, compared to conventionally melted glasses. On the other hand, they can be prepared very purely due to the use of the special chemical starting compounds.
Metalinguistik im Wandel : die "kognitive Wende" in Wissenschaftstheorie und Linguistik (1997)

Dieser Sammelband thematisiert wissenschaftstheoretische Grundlagenprobleme der Linguistik als kognitiver Wissenschaft. Dabei wird von der Erkenntnis ausgegangen, dass in den letzten etwa zwei Jahrzehnten nicht nur in der Linguistik, sondern auch in der Wissenschaftstheorie -kognitive Wenden- stattfanden. Somit stellt sich die Frage, unter welchen Bedingungen und mit welchen Konsequenzen die -kognitive Wende- in der Linguistik und die -kognitive Wende- in der Wissenschaftstheorie miteinander in Beziehung gebracht werden konnen. Die Beitrage des Bandes diskutieren neue Ansatze zur Wissenschaftstheorie der Linguistik, die Antworten auf diese Frage darstellen.
Mixed Polyelectrolyte Brush from Oppositely Charged Polymers for Switching of Surface Charge and Composition in Aqueous Environment (2003)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTMixed Polyelectrolyte Brush from Oppositely Charged Polymers for Switching of Surface Charge and Composition in Aqueous EnvironmentNikolay Houbenov, Sergiy Minko, and Manfred StammView Author Information Institut für Polymerforschung Dresden, Hohe Strasse 6, 01069 Dresden, Germany, and Department of Chemistry, Clarkson University, Potsdam, New York 13699-5810 Cite this: Macromolecules 2003, 36, 16, 5897–5901Publication Date (Web):July 12, 2003Publication History Received13 February 2003Revised6 June 2003Published online12 July 2003Published inissue 1 August 2003https://pubs.acs.org/doi/10.1021/ma0341869https://doi.org/10.1021/ma0341869rapid-communicationACS PublicationsCopyright © 2003 American Chemical SocietyRequest reuse permissionsArticle Views1990Altmetric-Citations156LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Homopolymers,Layers,Polymers,Silicon,Thickness Get e-Alerts
Diagnosis of Solid State DC/DC Cascaded Converter Faults in Hybrid Electric Automotive Power Systems (2006)

<div class="htmlview paragraph">Advancements in high-power semiconductor technology have opened new avenues for application of power electronics converters in safety critical applications such as in a hybrid vehicle automotive power system. Faults occurring in such application specific solid state converters can lead to fatal consequences as compared to their mechanical counterparts. This paper discusses the use of statistical moments to detect and identify faults. Existing system current and voltage sensors are used without the need for any additional sensors. The technique not only detects system malfunction, but provides information on the device under fault and the nature of the fault. An accurate knowledge of the same will allow appropriate action to be taken to avoid propagation of fault that may lead to catastrophic failure.</div>
Policing congestion response in an internetwork using re-feedback (2005)

This paper introduces a novel feedback arrangement, termed re-feedback. It ensures metrics in data headers such as time to live and congestion notification will arrive at each relay carrying a truthful prediction of the remainder of their path. We propose mechanisms at the network edge that ensure the dominant selfish strategy of both network domains and end-points will be to set these headers honestly and to respond correctly to path congestion and delay, despite conflicting interests. Although these mechanisms influence incentives, they don't involve tampering with end-user pricing. We describe a TCP rate policer as a specific example of this new capability. We show it can be generalised to police various qualities of service. We also sketch how a limited form of re-feedback could be deployed incrementally around unmodified routers without changing IP.
Insertion-deletion polymorphisms (indels) as genetic markers in natural populations (2008)

With an increasing amount of sequence information gathered from non-model organisms, we suggest that indels will come to form an important source of genetic markers, easy and cheap to genotype, for studies of natural populations.
Analysis of the probability distribution of the baseline wander effect for baseband pam transmission with application to gigabit ethernet (2005)

Communication systems that employ baseband transmission (i.e. signal spectrum centered around 0 Hz) may suffer from the baseline wander (BLW) phenomenon. This phenomenon occurs when the signal has to pass through a highpass filter element in the transmission path (e.g. a transformer in the line interface). A long sequence of symbols with constant value should generate a signal with constant level, but the signal will decay towards zero due to the highpass element. An example of a communication standard where baseband transmission is used with a DC-coupled channel is Ethernet. It can be shown that for baseband pulse amplitude modulation (PAM), the baseline wander phenomenon increases the dynamic range of the signal by a factor of 2, in worst case. This increases the cost of the receiver (for example, another bit may be needed in the analog to digital converter). However, the signal will reach its extreme values with very low probability, so it seems wasteful to design for worst case. It may be more economical to design for a smaller dynamic range, but then there must be a way to understand the probability that the signal will exceed this range. This can be done by using the probability distribution of the signal in the presence of BLW, which is calculated approximately in this paper.
Infrastructure Cost Comparison of Running Web Applications in the Cloud Using AWS Lambda and Monolithic and Microservice Architectures (2016)

Large Internet companies like Amazon, Netflix, and LinkedIn are using the microservice architecture pattern to deploy large applications in the cloud as a set of small services that can be developed, tested, deployed, scaled, operated and upgraded independently. However, aside from gaining agility, independent development, and scalability, infrastructure costs are a major concern for companies adopting this pattern. This paper presents a cost comparison of a web application developed and deployed using the same scalable scenarios with three different approaches: 1) a monolithic architecture, 2) a microservice architecture operated by the cloud customer, and 3) a microservice architecture operated by the cloud provider. Test results show that microservices can help reduce infrastructure costs in comparison to standard monolithic architectures. Moreover, the use of services specifically designed to deploy and scale microservices reduces infrastructure costs by 70% or more. Lastly, we also describe the challenges we faced while implementing and deploying microservice applications.
Alkylsubstituierte Cyclopentadienylvanadium(V)-Komplexe: <sup>t</sup>C<sub>4</sub>H<sub>9</sub>N=VCp<sup>R</sup>Cl<sub>2</sub> / Alkylated Cyclopentadienylvanadium (V) Complexes: <sup>t</sup>C<sub>4</sub>H<sub>9</sub>N =VCp<sup>R</sup>C l<sub>2</sub> (2000)

The synthesis of alkylated η 5 -cyclopentadienylvanadium(V) complexes t C 4 H 9 N=VCp R Cl 2 (Cp R = C 5 H 4 R, C 5 H 3 R 2 , C 5 HMe 4 , C 5 Me 5 ) is described. The compounds have been investigated by 51 V NMR spectroscopy; the 51 V resonances are found downfield of the unsubstituted complex t C 4 H 9 N=V(η 5 -C 5 H 5 )Cl 2 . The deshielding of the 51 V nucleus increases with the number of substituents R
Conformationally Constrained Anesthetic Steroids That Modulate GABA<sub>A</sub> Receptors (2000)

Various cyclic ether and other 3 alpha-hydroxyandrostane derivatives bearing a conformationally constrained hydrogen-bonding moiety were prepared. Their anesthetic potency and their binding affinity for GABA(A) receptors, measured by intravenous administration to mice and inhibition of [(35)S]TBPS binding to rat whole brain membranes, were compared with that of known anesthetic 3 alpha-hydroxypregnan-20-ones. Synthetic steroids with similar in vitro and in vivo activities to the endogenous 3 alpha-hydroxypregnan-20-ones all had an ether oxygen on the beta-face of the steroid D-ring. These results suggest that for optimal GABA(A) receptor modulation, the hydrogen bond-accepting substituent should be near perpendicular to the plane of the D-ring on the beta-face of the steroid.
Linearization and efficiency enhancement of the RF power amplifier by the even-order nonlinear signal injection (2015)

In this paper a broadband RF power amplifier operating at frequency range 0.75 GHz to 1.25 GHz is linearized by the even-order nonlinear signals at frequencies around the second harmonics that are inserted at the amplifier transistor gate and drain throughout the broadband matching circuits that provide high amplifier efficiency as well as adequate power level of the injected signal for the linearization. The effects of the transistor input (gate) second harmonic impedance on the amplifier efficiency is examined in addition to the analysis of the influence of the output (drain) second harmonic impedance performed earlier. The amplifier linearization is carried out for two-tone test characterized by different frequency interval between signals up to 100 MHz for various signal power levels as well as for WCDMA digitally modulated signal.
Estimation of Formation Hydraulic Properties from Analysis of Regular Operations Data (2001)

Abstract We propose to use regular pumping rate - pumping pressure data for estimating the formation hydraulic properties in the vicinity of wellbore without interrupting the operations. A distinctive feature of our analysis is that we account for the effects of pumping preceding the test interval. We derive our model from the same assumptions as in a standard pressure draw-down or pressure build-up test analysis. We introduce an additional parameter characterizing an effective pumping rate prior to the test. This parameter is of crucial importance for our procedure because there is no shut-in period preceding the test during regular operations. Moreover, we demonstrate that accounting for this parameter does affect analysis of a traditional pressure draw-down or build-up test as well. Our method produces good data matching, and the results are stable with respect to the selection of the portion of data for fitting. We derive our conclusions after analyzing almost entire data set, rather than only a portion of the pressure fall-off or build-up curve. This makes the results more reliable and stable with respect to measurement errors. The new method we have developed is implemented in a code named ODA (Operational Data Analysis). This program incorporates a special curve-fitting procedure which we designed for our method to significantly simplify the problem and reduce the amount of computations. Therefore, the analysis can be preformed on a laptop computer.
ChemInform Abstract: SYNTHESIS, REDOX CHARACTERISTICS, AND IN VITRO NOREPINEPHRINE UPTAKE INHIBITING PROPERTIES OF 2‐(2‐MERCAPTO‐4,5‐DIHYDROXYPHENYL)ETHYLAMINE (6‐MERCAPTODOPAMINE) (1980)

Abstract (V), von denen (III) und (IV) in 76%iger Gesamt‐ausbeute erhalten werden.
Electric and laser energy for endoscopic surg (1999)

Improvements in surgery have focused on refinements in the ability to dissect and limit blood loss. The electrosurgery unit (ESU) and laser (light amplification by stimulated emission of radiation) have been widely used in recent endoscopic surgery. ESU is a form of surgery in which high-frequency (100 kHz-5 MHz) electric currents are used to incise, destroy, and remove tissue and to seal blood vessels in order to maintain hemostasis. The use of lasers in surgery has added a new dimension to operative technique through increased precision, improved hemostasis, and less tissue manipulation. This paper aims to explain the basic principles and applications of electrosurgery and lasers.
Calibration of BOLD fMRI using breath holding reduces group variance during a cognitive task (2006)

The proportionality of blood oxygen level-dependent (BOLD) response during a cognitive task and that from a hypercapnic challenge was investigated in cortical structures involved in working memory (WM). Breath holding (BH) following inspiration was used to induce a BOLD response characteristic of regional vasomotor reactivity but devoid of metabolic changes. BOLD effects measured during BH were used to normalize individual subject activations during WM, which effectively reduced the confounding influence of individual- and region-specific differences in hemodynamic responsivity common to both tasks. In a study of seven subjects, the BH calibration reduced intersubject variability in WM effect amplitude by 24.8% (P < 0.03). Reduced intersubject variability resulted in a 23.7% increase in group WM activation voxel extent significant at P < 0.001, with further increases at more stringent thresholds. Because the BH task does not require CO(2) inhalation or other invasive manipulations and is broadly applicable across cortical regions, the proposed approach is simple to implement and may be beneficial for use not only in quantitative group fMRI analyses, but also for multicenter and longitudinal studies.
Actividad física competitiva para niños: consideraciones de la psicología del deporte (1991)

To identify and characterize aspirin sensitivity, over 500 oral aspirin challenges have been performed in patients since 1970. Protocols were developed, and an aspirin desensitization process was created as an extension of the challenge protocol. Without exception, desensitization has been achieved in 66 of 66 consecutive aspirin-sensitive asthmatics. There is also cross-desensitization with nonsteroidal anti-inflammatory drugs (NSAIDs) in the limited number of patients studied. After desensitization with either aspirin or NSAIDs, an interruption of continuous therapy is followed by a reappearance of sensitivity. Patients must be cautioned about this and the possibility of a severe reaction should aspirin be reintroduced after aspirin avoidance for 2-5 days.