gebhart/patrepeval huggingface dataset:
Stress-induced eating. (1994)

Stress is widely thought to lead to overeating. Studies of stress-induced eating have tested two models. One has tested whether stress increases eating in all exposed organisms and has been tested primarily with animals and physical stressors. The other has tested individual differences in vulnerability to stress-induced eating and has tested only human subjects and psychological stressors. The most consistent set of findings shows that "restrained" eating predicts vulnerability among women; we conclude that for the stressors studied to date, the individual-difference model has received stronger support. Because the question motivating much of this research is whether stress-induced eating causes obesity, future research should assess the effect of stress on weight-change more directly.
Facilitating a Generic Communication Interface to Distributed Energy Resources: Mapping IEC 61850 to RESTful Services (2010)

As the power system evolves into a smarter and more flexible state, so must the communication technologies that support it. A key requirement for facilitating the distributed production of future grids is that communication and information are standardized to ensure interoperability. The IEC 61850 standard, which was originally aimed at substation automation, has been expanded to cover the monitoring and control of Distributed Energy Resources (DERs). By having a consistent and well-defined data model the standard enables a DER aggregator, such as a Virtual Power Plant (VPP), in communicating with a broad array of DERs. If the data model of IEC 61850 is combined with a set of contemporary web protocols, it can result in a major shift in how DERs can be accessed and coordinated. This paper describes how IEC 61850 can benefit from the REpresentational State Transfer (REST) service concept and how a server using these technologies can be used to interface with DERs as diverse as Electric Vehicles (EVs) and micro Combined Heat and Power (μCHP) units.
Flash Photolytic Generation of a Dithio Carbocation from 1,3-Dithiolane Derivatives and Its Reaction with Nucleophiles (1991)

Abstract 2-Phenyl-1,3-dithiolanylium ion is generated as a transient intermediate by flash photolysis of aqueous ethanol and acetonitrile solutions of 2-methoxy and other dithiolane derivatives with a xenon lamp. Decay of the absorption (342 nm) of the cation generated from the 2-methoxy derivative follows pseudo-first-order kinetics. Rate constants were measured for the reaction of the cation with various nucleophiles. Decay curves for the cations generated from 2-arylthio and 2-sulfonyl derivatives are steep and show second-order kinetic character owing to the recombination of the cation with the counter anions (thiolate and sulfinate).
Clonal expansion of abnormal B cells in old NZB mice. (1987)

The spleens of old NZB mice have an abnormal population of B cells with extra chromosomes. These hyperdiploid B cells manifest increased proliferative capacity; they grow in (NZB X DBA/2)F1 spleens after intravenous injections. Molecular analysis of individual old NZB and F1 passaged spleens demonstrate that hyperdiploid cells represent a clonal or oligoclonal expansion of B cells. All spleens with at least 10% hyperdiploid cells demonstrated both heavy and kappa light chain immunoglobulin gene rearrangements by Southern blot hybridization. None of the hyperdiploid spleens from old NZB mice had lambda rearrangements and only one of five showed evidence of clonal rearrangement of the TCR-beta gene. One also had a VK10 clonal rearrangement. Elevated p53 oncogene protein was observed in NZB hyperdiploid spleen cells; however, no p53 or other oncogene rearrangements or amplifications were seen. Hyperdiploid cells were IgM-bright, IgD-dull, Ia+, dull B220, Thy-1-, and Ly-1-dull. Spleens with hyperdiploid B cells had increased percentages of Ly-1 B cells. The data suggest that hyperdiploid cells in old NZB mice represent clonal expansion of B cells and that they may represent an intermediate stage between autoimmunity and malignancy.
Statistical analysis of the social network and discussion threads in slashdot (2008)

We analyze the social network emerging from the user comment activity on the website Slashdot. The network presents common features of traditional social networks such as a giant component, small average path length and high clustering, but differs from them showing moderate reciprocity and neutral assortativity by degree. Using Kolmogorov-Smirnov statistical tests, we show that the degree distributions are better explained by log-normal instead of power-law distributions. We also study the structure of discussion threads using an intuitive radial tree representation. Threads show strong heterogeneity and self-similarity throughout the different nesting levels of a conversation. We use these results to propose a simple measure to evaluate the degree of controversy provoked by a post.
A three-microphone acoustic reflection technique using transmitted acoustic waves in the airway (2013)

The acoustic reflection technique noninvasively measures airway cross-sectional area vs. distance functions and uses a wave tube with a constant cross-sectional area to separate incidental and reflected waves introduced into the mouth or nostril. The accuracy of estimated cross-sectional areas gets worse in the deeper distances due to the nature of marching algorithms, i.e., errors of the estimated areas in the closer distances accumulate to those in the further distances. Here we present a new technique of acoustic reflection from measuring transmitted acoustic waves in the airway with three microphones and without employing a wave tube. Using miniaturized microphones mounted on a catheter, we estimated reflection coefficients among the microphones and separated incidental and reflected waves. A model study showed that the estimated cross-sectional area vs. distance function was coincident with the conventional two-microphone method, and it did not change with altered cross-sectional areas at the microphone position, although the estimated cross-sectional areas are relative values to that at the microphone position. The pharyngeal cross-sectional areas including retropalatal and retroglossal regions and the closing site during sleep was visualized in patients with obstructive sleep apnea. The method can be applicable to larger or smaller bronchi to evaluate the airspace and function in these localized airways.
The Microbiological Origin of Fluorescence Observed in Plaque on Dentures during QLF Analysis (2006)

The aim of this study was to determine the microbiological origin of plaque fluorescence observed during quantitative light-induced fluorescence (QLF) analysis. Plaque was sampled from dentures, because of easy accessibility and the homogeneous background provided by the denture tooth during imaging, and the acknowledged comparability to occlusal plaque. Forty removable poly(methyl methacrylate) dentures were screened for the presence of fluorescent plaque deposits during QLF analysis. Dentures were photographed, QLF images were recorded and samples of fluorescent plaque were taken. Plaque samples were cultured on fastidious anaerobe agar, Wilkins Chalgren agar and Sabourauds dextrose agar. Plates were screened under QLF and fluorescent colonies were subcultured and identified. Areas of red, orange and green fluorescence were detected on the fitting and non-fitting surfaces of dentures. The red and orange fluorescing species were Prevotella melaninogenica, Actinomyces israelii and Candida albicans, which are generally acknowledged to be secondary colonisers, present in more mature plaque. Green fluorescence was observed in streptococcal species (early colonisers) and Fusobacterium nucleatum (important organism in plaque development). Non-fluorescent colonies were also cultured. Plaque which accumulates on susceptible surfaces tends to be associated with caries, but it may be its maturity, rather than the presence of cariogenic streptococci, that is more likely to provide a microbiological link between red fluorescence and caries.
Skeletal muscle satellite cell transplantation (2003)

Cell transplantation is currently gaining a growing interest as a potential new means of improving the prognosis of patients with cardiac failure. The basic assumption is that left ventricular dysfunction is primarily caused by the loss of a critical number of cardiomyocytes and that their replacement by new contractile cells could functionally 'regenerate' postinfarction scars in which these cells are implanted. Primarily for practical reasons, autologous skeletal myoblasts have been the first to undergo clinical trials but other cell types are also considered, particularly bone marrow stem cells which are attractive because of their autologous origin and their purported cardiomyocyte/endothelial transdifferentiation potential in response to cues present in the target organ. However, several key issues still need to be addressed including (1) the optimal type of donor cells, (2) the mechanism by which cell engraftment improves cardiac function, (3) the optimization of cell survival, and (4) the potential benefits of cell transplantation in nonischemic dilated cardiomyopathies. In parallel to the experimental studies designed to address these issues, clinical trials are underway and their results should hopefully allow the assessment of to what extent cellular therapy may improve the outcome of patients with heart failure.
Perrow, M. R., and A. J. Davy, editors. 2002. Handbook of Ecological Restoration. Volume 1: Principles of Restoration; Volume 2: Restoration in Practice. Cambridge University Press, Cambridge, UK. (2003)

Allen, A., S. Kercher, D. Larkin, H.-N. Morzaria-Luna and M. Peach 2003. Perrow, M. R., and A. J. Davy, editors. 2002. Handbook of Ecological Restoration. Volume 1: Principles of Restoration; Volume 2: Restoration in Practice. Cambridge University Press, Cambridge, UK.. Conservation Ecology 7(2):4. https://doi.org/10.5751/ES-00516-070204
Bioavailability of transdermal methimazole in a pluronic lecithin organogel (PLO) in healthy cats (2002)

The antithyroid drug methimazole is widely used for the medical management of feline hyperthyroidism. Recently, custom veterinary pharmacies have offered methimazole in a transdermal gel containing pluronic and lecithin (PLO), with anecdotal evidence of efficacy. The purpose of this study was to determine the bioavailability, relative to i.v. and oral routes of administration, of transdermal methimazole in a PLO gel in cats. Six healthy adult cats were assigned to receive 5 mg of methimazole by the i.v., oral, or transdermal routes, in a randomized triple crossover protocol with 1 week washout between doses. Blood samples were taken for high performance liquid chromatography (HPLC) determination of serum methimazole, at 0, 5, 15, 30, 60 min, and 2, 4, 6, 12 and 24 h after dosing. Methimazole absorption following transdermal administration was poor and variable, with only two of six cats achieving detectable serum methimazole concentrations at any time point following transdermal administration. Area under the concentration-time curve (AUC), maximum concentration (Cmax), and absolute bioavailability were all significantly lower for the transdermal route (0.39 +/- 0.63 microg h/mL, 0.05 +/- 0.09 microg/mL, and 11.4 +/- 18.7%, respectively) than for either i.v. (7.96 +/- 4.38 microg h/mL, 3.34 +/- 2.00 microg/mL, 100%) or oral routes (2.94 +/- 1.24 microg h/mL, 0.51 +/- 0.15 microg/mL, 40.4 +/- 8.1%). The results of this study indicate generally low to undetectable bioavailability of methimazole in a lecithin/pluronic gel given as a single transdermal dose to healthy cats, although one individual cat did achieve nearly 100% transdermal bioavailability relative to the oral route.
Physicochemical Characterization of Creatine<i>N</i>-Methylguanidinium Salts (2010)

Creatine is widely used as a dietary supplement for body builders to enhance athletic performance. As the monohydrate, its low solubility in water and high dose lead to water retention and gastrointestinal discomfort. Hence, alternative creatine derivatives with enhanced water solubility and potential therapeutic advantages have been synthesized. As a zwitterionic compound, creatine can form salts at the N-methyl guanidinium or carboxylic acid functional groups. In this study, we determined the aqueous solubilities and partition coefficients of six N-methyl guanidinium salts of creatine compared to those of creatine monohydrate; two of these were new salts, namely, creatine mesylate and creatine hydrogen maleate. The aqueous solubilities of the salts were significantly more than that of creatine monohydrate with the hydrochloride and mesylate being 38 and 30 times more soluble, respectively. The partition coefficients of the creatine salts were very low indicating their relatively high polarity. Permeabilities of creatine pyruvate, citrate, and hydrochloride in Caco-2 monolayers were compared to that of creatine monohydrate. Aside from the creatine citrate salt form that had reduced permeability, there were no significant differences in permeability characteristics in Caco-2 monolayers. Typical of an amphoteric compound, creatine is least soluble in the pH region near the isoelectric point.
PRESSURE SWING ADSORPTION IN NON-ISOTHERMAL, NON-EQUILIBRIUM CONDITIONS : SINGLE ADSORBATE (1991)

A two bed pressure swing adsorber has been modelled for a one adsorbate system operating non-isothermally and constrained by a non-linear, Langmuir type adsorption isotherm. Using 5A molecular sieves to separate ethane and carbon dioxide from nitrogen, it was found that a linear driving force equation gave predictions of concentrations in both adsorbed and fluid phases, and predictions of temperature that compared well with experimental values. Both the transient region of operation and cyclic steady-state have been considered
Adaptive filtering in sub-bands (2003)

Adaptive filtering in subbands, that is adapting several short filters in parallel on subsampled frequency subbands, is an attractive alternative to implementing a long adaptive FIR (finite-impulse response) filter, due to its computational efficiency and faster convergence. The subsampling process introduces aliased versions of the original signals; it is shown how to annihilate these by adequate adaptive cross terms. The computational complexity is improved nearly proportionally to the number of subbands, and the conference speed is improved as well, making this scheme attractive for applications like acoustic echo cancellation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Esters of (S)-1,2-propanediol and (R,R)-2,3-butanediol — Chiral Compounds Inducing Cholesteric Phases with a Helix Inversion · (1987)

Mesogenic chiral esters of optically active (S)-1,2-propanediol and (R,R)-2,3-butanediol were synthesized. The compounds, added to a nematic phase induce cholesteric phases exhibiting a helix inversion with temperature variation. This effect is independent of the molecular structure of the nematic solvent. The inversion temperature varies only slightly with concentration but can be influenced by the mesogenic substituent.
All-Optical Measurement-Based Quantum-Information Processing in Quantum Dots (2006)

Parity measurements on qubits can generate the entanglement resource necessary for scalable quantum computation. Here we describe a method for fast optical parity measurements on electron spin qubits within coupled quantum dots. The measurement scheme, which can be realized with existing technology, consists of the optical excitation of excitonic states followed by monitored relaxation. Conditional on the observation of a photon, the system is projected into the odd/even-parity subspaces. Our model incorporates all the primary sources of error, including detector inefficiency, effects of spatial separation and nonresonance of the dots, and also unwanted excitations. Through an analytical treatment we establish that the scheme is robust to such effects. Two applications are presented: a realization of a controlled-NOT gate, and a technique for growing large scale graph states.
Iron, DtxR, and the regulation of diphtheria toxin expression (1994)

In recent years considerable advances have been made in the understanding of the molecular basis of iron-mediated regulation of diphtheria toxin expression. The tox gene has been shown to be regulated by the heavy metal ion-activated regulatory element DtxR. In the presence of divalent heavy metal ions, DtxR becomes activated and binds to a 9 bp interrupted palindromic sequence. The consensus-binding site has been determined by both the sequence analysis of DtxR-responsive operators cloned from genomic libraries of Corynebacterium diphtheriae as well as by in vitro genetic methods using cyclic amplification of selected targets (CASTing). It is now clear that DtxR functions as a global iron-sensitive regulatory element in the control of gene expression in C. diphtheriae. In addition, the metal ion-activation domain of DtxR is being characterized by both mutational analysis and determination of the X-ray structure at 3.0 A resolution.
5‐azacytidine inhibits nonsense‐mediated decay in a <scp>MYC</scp> ‐dependent fashion (2014)

Nonsense-mediated RNA decay (NMD) is an RNA-based quality control mechanism that eliminates transcripts bearing premature translation termination codons (PTC). Approximately, one-third of all inherited disorders and some forms of cancer are caused by nonsense or frame shift mutations that introduce PTCs, and NMD can modulate the clinical phenotype of these diseases. 5-azacytidine is an analogue of the naturally occurring pyrimidine nucleoside cytidine, which is approved for the treatment of myelodysplastic syndrome and myeloid leukemia. Here, we reveal that 5-azacytidine inhibits NMD in a dose-dependent fashion specifically upregulating the expression of both PTC-containing mutant and cellular NMD targets. Moreover, this activity of 5-azacytidine depends on the induction of MYC expression, thus providing a link between the effect of this drug and one of the key cellular pathways that are known to affect NMD activity. Furthermore, the effective concentration of 5-azacytidine in cells corresponds to drug levels used in patients, qualifying 5-azacytidine as a candidate drug that could potentially be repurposed for the treatment of Mendelian and acquired genetic diseases that are caused by PTC mutations.
Resonant tunneling of Si nanocrystals embedded in Al2O3 matrix synthesized by vacuum electron-beam co-evaporation (2002)

High vacuum electron-beam co-evaporation, followed by N2 annealing at 500 °C is used for preparing of silicon nanocrystals (Si NCs) embedded in Al2O3 dielectric matrix. X-ray diffraction and transmission electron microscopy are used to investigate the structures of Si+Al2O3 films and estimate the mean diameter of the Si NCs. The electrical properties of the diode containing Si NCs embedded in Al2O3 are studied at room temperature and resonant tunneling effect with large voltage gap is observed. A circuit model based on resonant tunneling is proposed to simulate the measured I–V curve.
Consequences of Increasing Resistance to Antimicrobial Agents (1998)

The correlation between in vitro bacterial susceptibility results and clinical outcome has been debated for many years. Bacterial resistance traits are more significantly correlated with failure of therapy than is an organism's susceptibility to an antimicrobial agent. We review the situations that have supported the clinical relevance of in vitro bacterial resistance. Those situations include: emergence, during therapy, of a new resistance marker not known before; selection of a resistant mutant or acquisition of a resistance gene during therapy; failure to recognize or take into account a new resistance mechanism; and superinfection with resistant bacteria. More information should be obtained in the future by performing studies oriented toward bacteriologically documented clinical failures and by better communication between microbiologists and physicians to correlate the in vitro data with host status, the pharmacokinetics of the antimicrobial agent, and the bacteriologic and clinical outcome.
Near-Optimal Separation of Treelike and General Resolution (2000)

Efficient carbon monoxide oxidation is important to reduce its impacts on both human health and the environment. Following a sustainable synthesis route toward new catalysts, nanosized Co<sub>3</sub>O<sub>4</sub> was synthesized based on extracts of microalgae: <i>Spirulina platensis</i>, <i>Chlorella vulgaris</i>, and <i>Haematococcus pluvialis</i>. Using the metabolites in the extract and applying different calcination temperatures (450, 650, 800 °C) led to Co<sub>3</sub>O<sub>4</sub> catalysts with distinctly different properties. The obtained Co<sub>3</sub>O<sub>4</sub> nanomaterials exhibited octahedral, nanosheet, and spherical morphologies with structural defects and surface segregation of phosphorous and potassium, originating from the extracts. The presence of P and K in the oxide nanostructures significantly improved their catalytic CO oxidation activity. When normalized by the specific surface area, the microalgae-derived catalysts exceeded a commercial benchmark catalyst. <i>In situ</i> studies revealed differences in oxygen mobility and carbonate formation during the reaction. The obtained insights may facilitate the development of new synthesis strategies for manufacturing highly active Co<sub>3</sub>O<sub>4</sub> nanocatalysts.
The challenge of competency assessment. (1999)

Regulatory agencies now require more than credentialing, quality assurance, and educational programs to prove that health care workers are competent. There is confusion over exactly what competency is and how we can assess it in an environment of strict cost restriction. This article presents an overview of the current situation and some techniques for assessing competencies. Emphasis is on clinical laboratory approaches.
Bi-layer, mode 2, four-arm spiral antennas (2007)

A bi-layer, four-arm, printed spiral antenna having a well-formed conical pattern with a simple, vertically oriented feed is proposed. Mode 2 performance is verified computationally and experimentally. A novel helical arm termination is also introduced and enhanced performance is demonstrated.
Check 'n' crash: combining static checking and testing (2005)

We present an automatic error-detection approach that combines static checking and concrete test-case generation. Our approach consists of taking the abstract error conditions inferred using theorem proving techniques by a static checker (ESC/Java), deriving specific error conditions using a constraint solver, and producing concrete test cases (with the JCrasher tool) that are executed to determine whether an error truly exists. The combined technique has advantages over both static checking and automatic testing individually. Compared to ESC/Java, we eliminate spurious warnings and improve the ease-of-comprehension of error reports through the production of Java counterexamples. Compared to JCrasher, we eliminate the blind search of the input space, thus reducing the testing time and increasing the test quality.