gebhart/patrepeval huggingface dataset:
Triggering mechanism of B lymphocytes. I. Effect of anti-immunoglobulin and enhancing soluble factor on differentiation and proliferation of B cells. (1975)

Stimulation of rabbit mesenteric lymphocytes with anti-immunoglobulin antibody (anti-Ig) for 24 hr (first stage of culture) followed by the addition of enhancing soluble factor (second stage of culture) induced the formation of IgG. The presence of mitotic inhibitors, such as cytosine arabinoside (Ara-C), hydroxyurea (HU), with anti-Ig for the first 24 hr of incubation did not inhibit the production of IgG induced by anti-Ig and soluble factor. The addition of cytochalasin-B in the first stage of culture with anti-Ig did not inhibit, but rather enhanced, the formation of IgG. On the other hand, the presence of Ara-C, HU, or cytochalasin-B with soluble factor in the second stage of culture completely inhibited the production of IgG. Soluble factor preferentially induced the uptake of thymidine of anti-Ig-stimulated cells. Lipopolysaccharide (LPS) also induced the proliferation of rabbit lymphocytes, but did not induce the IgG production of anti-Ig-stimulated cells. However, LPS-stimulated cells formed a significant amounf of IgG when they were cultured with soluble factor. Anti-Ig-stimulated cells absorbed the enhancing activity of soluble factor, but non-stimulated cells did not absorb the activity. These results showed that cross-linkage of Ig receptors or LPS receptors with anti-Ig or LPS induced the formation of acceptor sites for soluble factor without the requirement of cell division and these activated cells started to proliferate and maturate to antibody-forming cells under the influence of soluble factor.
Research of Graph-Based Workflow Access Control (2008)

Using graph transformation as a formalism to specify access control has several advantages, from the intuition provided by the visual aspect to the precise semantics and the systematic verification of constraints. Graph transformations provide a uniform and precise framework for the specification of access control policies. This article presents specification formalisms for workflow access control policies using graph transformation. The authorization states are represented by graphs and state transition by graph transformation. The proposed formalization provides an intuitive description for the manipulation of graph structures as they occur in workflow access control and a precise specification of consistency conditions on graphs and graph transformations. We specifies a type graph to represents the type information in the graph transformation for workflow access control, a set of rules to build the system states and sets of positive and negative constraints to specify wanted and unwanted framework. Using formal properties of graph transformation, it is can to detect inconsistencies between a rules and a constraint and lay the foundation for their resolutions. We present an algorithm to automatically check and eliminate conflicts between rules and positive and negative constraints.
[Application of two dimensional electrophoresis,western blot and mass spectrum to screen markers of endometriosis]. (2005)

The protein expression spectra of eutopic endometrium from patients with endometriosis are significantly different from those of the controls, and the anti-endometrial autoantibodies against vimentin, beta-actin and ATP synthase beta subunit may be induced.
Integrated Diode Phase Shifters and Performance in a 502-Element X-Band Array (2005)

The results of fabricating 502 integrated 3-bit PIN diode phase shifters and dipole radiators will be discussed. These phase shifters consist of chip PIN diodes mounted on 25-mil alumina microstrip. A horizontally polarized dipole has been printed on the same structure, giving a complete phased array element. Considerations in the program were given for diode and circuit variations and their effects on phased array performance. A transmissive phased array has been fabricated with these elements and the performance will be discussed in terms of the phase shifter manufacturing tolerances.
Single Osteon Micromechanical Testing (1999)

I. Introduction ..........................................................................................................................271 II. Elements of Micromechanical Testing ................................................................................272
Campylobacter etiology in human gastroenteritis demonstrated by antibodies to acid extract antigen (1987)

Campylobacter antibodies of the immunoglobulin G (IgG), IgM, and IgA classes were determined by enzyme immunoassay with acid glycine extract antigen in patients and controls involved in two Campylobacter outbreaks and in 266 unselected patients with acute enteritis. The assay showed a specificity of 99% for each immunoglobulin class in sera from 200 healthy blood donors. Elevated Campylobacter antibody titers were shown in 97% of stool culture-positive patients involved in the outbreaks. Rapid changes of IgA and IgM Campylobacter antibodies were typical of the early phase of serologic response in the outbreaks and thus offered the best diagnostic value in the serologic diagnosis of acute campylobacteriosis. In unselected patients with acute enteritis, the assay revealed elevated Campylobacter antibody titers in 37 patients, of whom only 12 had had positive Campylobacter stool cultures. In the sera of patients with other bacterial findings in addition to high titers of Campylobacter antibodies, no cross-reacting antibodies were found, but there was evidence of several mixed infections.
Synthetic Study of Salinomycin (Synthesis of C18-C29 Fragment) (1986)

With regard to our continuing investigation in the total synthesis of salinomycin , a polyether ionophore antibiotic, preparation of the necessary three fragments, (I), (IV), (V) for the synthesis of salinomycin was accomplished.Synthetic plane of salinomycin was shown in scheme 1.As reported in this
Acoustic lens design by genetic algorithms (2004)

A survey of acoustic devices for focusing airborne sound is presented. We introduce a new approach to design high quality acoustic lenses based on arrays of cylindrical rigid scatterers in air. A population based stochastic search algorithm is used in conjunction with the multiple scattering theory to optimize a cluster of cylinders that focuses the sound in a prefixed focal point. Various lenses of different sized clusters, for different frequencies and with different focal lengths are presented. In general three focusing phenomena are remarked, focusing due to refraction, diffraction and focusing due to multiple scattering. The dependency on the frequency of the incident sound and the focal distance is analyzed indicating that higher frequencies and smaller focal distances favor larger amplifications in thin lenses based on multiple scattering. Furthermore, the robustness of a designed acoustic lens is studied, examining the focusing effect against errors in the cylinders' positions and their radius.
Detection of infectious salmon anaemia virus (ISAV) by RT-PCR after cohabitant exposure in Atlantic salmon Salmo salar (2001)

A reverse transcription polymerase chain reaction (RT-PCR) was used to study the early phase of infectious salmon anaemia virus (ISAV) infection in Atlantic salmon Salmo salar L. The detection threshold for the RT-PCR was estimated to be 0.01 to 0.1 TCID50. A protocol that closely mimics the conditions in populations of farmed salmon was used. The major port of ISAV entry was most likely the gills, but oral entry could not be excluded. The gills and heart were RT-PCR positive 5 d post infection and there was a rapid viraemic spread of the virus after entry. Ten or more days post infection, most organs yielded RT-PCR positive samples. The viral load of the fish followed a 2-phase curve with the first maximum at approximately 15 d and a minimum around 25 d. After 25 d, there was a steady increase in viral load until all sampled organs eventually became positive. In an experiment in which the transportation of material from field to diagnostic laboratory was simulated, the transportation of whole fish was found to be optimal for the performance of RT-PCR.
Psychostimulant Use in the Rehabilitation of Individuals with Traumatic Brain Injury (2002)

This article reviews the controlled research literature on the use of these drugs in TBI and presents preliminary data from the authors' laboratory that extends these findings. Some of the common research pitfalls that have limited progress in research on these drugs are discussed.
Predictors of Treatment Choice in Lumbar Spinal Stenosis (2012)

A greater understanding of baseline characteristics that influence patient choices in the treatment of lumbar spinal stenosis can aid the patient and the surgeon during the shared decision-making process.
Structure and Permeation Characteristics of an Aqueous Ethanol Solution of Organic−Inorganic Hybrid Membranes Composed of Poly(vinyl alcohol) and Tetraethoxysilane (2002)

To inhibit the swelling of PVA membranes in aqueous alcohol solutions, which leads to lowered water permselectivity during separation, organic−inorganic hybrid membranes composed of poly(vinyl alcohol) (PVA) and tetraethoxysilane (TEOS) were prepared. When an aqueous solution of 85 wt % ethanol was permeated through the PVA/TEOS hybrid membranes during pervaporation, the separation factor for water permselectivity increased, but the permeation rate decreased, with increasing TEOS content. We concluded that the decreased permeation rate was caused by decreasing the degree of swelling of the membrane. Therefore, this decrease in the degree of swelling and the increase in membrane density were due to the formation of hydrogen bonds between the silanol groups resulting from the hydrolysis of TEOS and the hydroxyl group of PVA. When the PVA and PVA/TEOS hybrid membranes were annealed, the separation factor of these membranes increased with increasing annealing temperature and time. The fact that annealing at higher temperatures promoted the dehydration−condensation reaction between PVA and TEOS in PVA/TEOS membranes was related to the enhanced permselectivity of the PVA/TEOS membranes.
A storage system for use with binary-digital computing machines (1949)

The requirement for digital computing machines of large storage capacity has led to the development of a storage system in which the digits are represented by a charge pattern on the screen of a cathode-ray tube. Initial tests have been confined to commercial tubes. Shortterm memory of the order of 0.2 sec is provided by the insulating properties of the screen material. Long-term memory is obtained by regenerating the charge pattern at a frequency greater than 5 c/s. The regeneration makes accurate stabilization of the position of the charge pattern on the c.r. tube unnecessary. The properties required of a storage system, and its operation as part of a machine, are stated. If such a machine were operated in the series mode, an instruction would be set up and obeyed in 600 μsec.
Endodontic filling materials – Past, present and future (2012)

Endodontically treated teeth are widely considered to be more susceptible to fracture than are vital teeth because of dehydration of dentin after endodontic therapy, excessive pressure during obturation, and removal of sound tooth structure. A new kind of resin canal filling material has been found that has properties desirable for root canal filling such as adhesion to dentin, good sealing ability and removability2.
Rousseau: The General Will and the Scandal of Politics (1993)

The high mortality upon enteric virus infection in piglets causes huge economic losses. To control these infections, potential causes for this high susceptibility for enteric virus infections in younger piglets were analyzed by comparing the intestinal barrier between 1-week, 2-week and 4-week-old piglets. In this study, histological staining was used to analyze morphological differences in intestinal villi, real-time qPCR was performed to assess mRNA expression levels of genes that were related to viral infection and differentiation of immune cells, and flow cytometry was utilized to measure the frequencies of T cells. According to the results obtained, 1-week-old piglets have intestinal villi with shallower crypts, less well developed epithelial cells and a more immature immune system compared to older pigs. Moreover, high amounts of enteric virus invasion-assisting proteins but low amounts of resistant proteins in 1-week piglets could also be a reason for the high susceptibility of 1-week-old piglets.
Deficiency of a surface membrane glycoprotein (Mo1) in man. (1984)

Deficiency of a granulocyte surface glycoprotein of 150,000-D had been associated with defective C3- and IgG-dependent phagocytosis in a patient with recurrent bacterial infections. By using monoclonal antibodies, we found that this patient's granulocytes, monocytes, and null cells were deficient in Mo1 (equivalent to OKM1 and Mac-1), a cell surface molecule consisting of two noncovalently linked glycoproteins of 155,000 and 94,000 D. The 155,000-D subunit is closely associated with the human complement receptor that recognizes C3bi and/or a further degradation product termed C3dg (C3bi receptor); the 94,000-D subunit has been shown to be shared, on normal cells, by two other surface membrane glycoproteins: lymphocyte function-associated antigen-1 (LFA-1) and P-150, 95. Both subunits of Mo1 were deficient on the patient's granulocytes as determined by immunoprecipitation with subunit-specific monoclonal antibodies as well as fluorescence analysis. Mol-deficient monocytes, like granulocytes, had defective C3-and IgG-dependent phagocytosis. Natural killing activity by the patient's peripheral blood leukocytes was normal. Mo1-deficient granulocytes and monocytes rosetted normally with sheep erythrocytes coated with C3bi. This rosetting was totally inhibited by a mixture of anti-Mo1 and anti-C3b (the major fragment of C3) receptor antibodies but not by either antibody alone. Since monoclonal antibodies to the 155,000-D subunit of Mo1 can inhibit C3bi receptor binding, immune phagocytosis, opsonized zymosan-induced degranulation, and superoxide generation by normal phagocytes (functions which are defective in Mo1-deficient cells), it appears likely that Mo1 deficiency may in part underlie the functional aberrations leading to recurrent bacterial infections in man.
A New Data-Gathering and Control System (1967)

The Automatic Electric C-2000 Data-Gathering and Control System represents recent innovations in the field of industrial control. The system consists of a master station complex located at the hub of a communication network, linking it to a number of remote stations. An unusually efficient communication message structure is employed which, when used in conjunction with a high-speed data set, results in an exceptionally high information rate. An efficient and effective message security scheme is employed. The system is modular on both a functional and a per-point basis, allowing it to be efficiently employed in installations of all sizes.
Application of Capillary Electrophoresis with Laser-Induced Fluorescence Detection for Determination of Methylmalonic Acid in Human Serum (1995)

Methylmalonic acid (MMA) in serum is an established marker of cobalamin deficiency. MMA and other short-chain dicarboxylic acids react with 1-pyrenyldiazomethane to form stable, highly fluorescent 1-pyrenylmethyl monoesters. We have analyzed these esters in human blood by capillary electrophoresis (CE) combined with laser-induced fluorescence detection, and here we describe our approach to achieve long-term reproducibility, which is a prerequisite for routine clinical application. To stabilize CE performance and to minimize solute adsorption to the capillary wall, we coated capillaries with linear polyacrylamide, used hydroxypropyl methylcellulose and dimethylformamide as buffer additives, and extensively diluted derivatized samples prior to injection. A discontinuous buffer system was used for sample stacking. Separation was performed in Tris-citrate buffer, pH 6.4, under reversed polarity conditions (negative potential at the inlet vial). The assay was linear for serum MMA concentrations in the range 0.1-200 mumol/L, the total run time was 26 min, the sample output was about 50 samples/24 h, and the coefficients of variation ranged between 3 and 12%, depending on the MMA concentration. Comparison of our assay with two established GC/MS methods demonstrated good correlation and measuring agreement.
How do porosity-inducing techniques affect antibiotic elution from bone cement? An in vitro comparison between hydrogen peroxide and a mechanical mixer (2008)

In terms of improving elution, the mixing drill piece seemed to be efficient. A relationship between surface porosity and elution efficacy was not observed.
Adenosine Receptors and Wound Healing, Revised (2006)

Recent studies have demonstrated that application of topical adenosine A2A receptor agonists promotes more rapid wound closure and clinical studies are currently underway to determine the utility of topical A2A adenosine receptor agonists in the therapy of diabetic foot ulcers. The effects of adenosine A2A receptors on the cells and tissues of healing wounds have only recently been explored. Here we summarize the evidence indicating that adenosine and selective adenosine agonists, acting at A2A receptors, promote the salutary functions of inflammatory cells, endothelial cells and fibroblasts in stimulating wound healing.
Social care of the orthopaedically handicapped in Denmark (1950)

(1950). Social care of the orthopaedically handicapped in Denmark. Australian Journal of Social Work: Vol. 4, No. 2, pp. 3-5.
Home spirometry and asthma severity in children (2006)

The usefulness of peak expiratory flow monitoring is disputed because of the unreliability of written peak flow diaries. The aim of the present study was to examine the relationship of peak flow and forced expiratory volume in one second (FEV1) variation to other estimates of asthma severity in children, using an electronic home spirometer with automatic data storage. Over a 3-month period, 36 children with mild-to-moderate persistent asthma recorded peak flow and FEV1 electronically twice daily and noted an asthma severity score in a written diary. Bronchial responsiveness was assessed at the beginning and bronchodilator response and asthma-specific quality of life at the end of the study. Variations in peak flow correlated significantly but weakly to bronchial responsiveness and bronchodilator response, but not to the asthma severity score or quality-of-life scores. Within-individual correlations between asthma severity scores and home spirometry indices and between peak flow and FEV1 were highly variable. In conclusion, variations in peak flow and forced expiratory volume in one second, obtained by home spirometry, show poor concordance with other indices of disease activity and with each other. This limits the usefulness of home spirometry in childhood asthma.
Labile plasma iron (LPI) as an indicator of chelatable plasma redox activity in iron-overloaded β-thalassemia/HbE patients treated with an oral chelator (2004)

Persistent levels of plasma nontransferrin bound iron (NTBI) have been associated with tissue iron overload and toxicity. We characterized NTBI's susceptibility to deferoxamine (directly chelatable iron [DCI]) and redox activity (labile plasma iron [LPI]) during the course of long-term, continuous L1 (deferiprone) treatment of patients with hemoglobin E disease and beta-thalassemia (n = 17). In 97% of serum samples (n = 267), the LPI levels were more than 0.4 microM (mean +/- SEM, 3.1 +/- 0.2 microM) and the percent transferrin (Tf) saturation more than 85 (111 +/- 6), whereas only in 4% of sera were the LPI levels more than 0.4 microM for Tf saturation less than 85%. Daily administration of L1 (50 mg/kg) for 13 to 17 months caused both LPI and DCI to decrease from respective initial 5.1 +/- 0.5 and 5.4 +/- 0.6 microM to steady mean levels of 2.18 +/- 0.24 and 2.81 +/- 0.14 microM. The steady lowest levels of LPI and DCI were attained after 6 to 8 months, with a half time (t(1/2)) of 2 to 3 months. Serum ferritin and red cell membrane-associated iron followed a similar course but attained steady basal levels only after 10 to 12 months of continuous treatment, with a t(1/2) of 5 to 7 months. These studies indicate that LPI and DCI can serve as early indicators of iron overload and as measures for the effectiveness of iron chelation in reducing potentially toxic iron in the plasma.
El papel de la mediación en la resolución del conflicto individual de trabajo (y II) (1) (2015)

El concepto de acceso a la justicia esta evolucionando drasticamente poniendo en evidencia la capacidad de la mediacion para satisfacer una parte de la demanda social de justicia. En el ambito laboral espanol la mediacion ya ha conquistado el mundo de las relaciones colectivas y ahora esta buscando su imprescindible papel en el campo de la resolucion del conflicto individual de trabajo como el derecho de las partes a resolver sus disputas a traves de medios informales y adecuados. Sin embargo, la realidad va muy por detras de nuestras propias leyes y palabras pues seguimos canalizando la resolucion de la conflictividad laboral individual a traves del procedimiento judicial y de la sentencia incapaz en muchos casos de satisfacer adecuadamente las necesidades de las partes.
Production of laccases A and B by a mutant strain of Trametes versicolor. (1986)

After induction, the wild type of Trametes versicolor produced two forms of laccase (A and B) in the ratio of 9 to 1. A UV-selected mutant strain of Trametes versicolor isolated on high concentrations of p-xylidine, p-cresol and phenol produced these laccases without induction in the ratio of 4 to 6. After induction with p-xylidine the production of laccase A increased significantly only in the mutant strain. Laccases A and B had catalytic activities proportional to the EPR spectroscopy-detected copper ions present. Several components were determined by electrophoretic analysis.
Parking Navigation and Payment System using IR Sensors and RFID Technology (2015)

The main problem in today's crowded parking facility is congestion and finding a vacant parking space. In this paper, a navigation method is proposed that minimizes the parking time, based on collected real-time vacancy information of parking slots. In the proposed method, a central server in the parking facility collects the information (using IR sensors) and estimates the occupancy of each parking slots. Then, the server uses this information collected in real time to calculate the best suitable parking slot for the user upon request. This path is then sent to user's smart-phone as response by the server which will then be displayed on an android application. This leads to the introduction of an eco-friendly payment system (using RFID technology), wherein no use of paper takes place. Automatic deduction of parking charge is taken care of on the server side, from users via RFID account and notification via SMS or Email is generated.
Combined orthogonal vector and pseudo-inverse approach for robust pattern recognition (1992)

A neural-based orthogonal vector with a pseudo-inverse approach for pattern recognition is presented. A method for generating N orthogonal vectors for an N-neuron network is also presented. This approach converges the input to the corresponding orthogonal vector representing the prototype vector. Moreover, it can restore an image to the original image and thus has error recovery capability. Patterns with 20% error were recognized, using English capital latters as an example. The robustness of this approach is obvious.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>