gebhart/patrepeval huggingface dataset:
Active Citizenship at Old Yarranlea State School (2006)

Considerations of Learning Futures are predicated on recognition of the extreme pace of change in contemporary societies and the need for education systems that prepare learners to participate in such dynamic environments. The precepts of active citizenship, which draw upon democratic and humanistic values to emphasise the importance of relationship building and community mindedness, provide both curriculum content for learners and mechanisms for change in school communities.This paper is an ethnographic evaluation of curriculum and pedagogy that examines the culture and perspectives which support active citizenship at Old Yarranlea State School. The paper proposes a metastrategic framework for implementing change, by developing processes that integrate the physical, intellectual, social and emotional components of the school community in a manner that is culturally inclusive, socially sustainable and engaged in the creation and re-creation of democratic principles. The result is an approach to curriculum planning that develops a unique school vision, identity and infrastructure and an approach to pedagogy that is an expansion and application of the curriculum content itself.
Reading Critics Reading (2001)

Abstract This book is among the first to examine French opera and ballet criticism during the first half of the nineteenth century both as a historical and a literary phenomenon. It thus provides a new and badly needed perspective for scholars and other commentators who have often been willing to treat the journalistic responses to such musical genres chiefly as a simple source of factual information. The essays, taken from a conference in Oxford in 1996, explore the kinds of problem encountered and the types of methodology that might be employed in trying to interpret these critical responses; they throw light on such aspects as the cultural attitudes underlying the writers’ rhetoric, the aesthetic stances and ideological agendas at play, and how modes of production influenced content.
[Comparative analysis of methods for laboratory diagnosis of Lyme's disease in early stages of infection]. (2003)

Different methods of laboratory diagnostics were comparatively analyzed in examining 25 patients at the early infection stage. Sera were measured by using various serological reactions. Specific antibodies were determined by using the reaction of indirect immune-fluorescence (RIIF), the immune-enzyme analysis (IEA) and the complement-binding reaction (CBR) in 83.1%, 54.4% and 12.5% of cases, respectively. Essential differences in sensitivity were detected between the above methods. RIIF was proven to be a reliable and sufficiently sensitive method in the laboratory diagnostics of Lyma's disease. While the use of two methods, i.e. RIIF and IEA, ensures the highest percentage of detection of antibodies to the causative agent of Lyma's disease.
A High-Resolution Proportional Chamber Positron Camera and Its Applications (1978)

A positron camera consisting of two high density proportional chambers is described. It provides a spatial resolution of 2.4 mm FWHM, a maximum data rate of 3000 c.p.s. and a sensitivity of 25 c.p.s. per μCi. Results of its application to angular correlation studies of condensed matter and to phantom and in vivo medical imaging are presented. A Fourier deconvolution technique is described for obtaining three-dimensional medical images. It uses a generalized matrix inversion by singular value decomposition to modify the low frequency Fourier components.
Single-mode UV-written buried channel waveguide lasers in direct-bonded neodymium-doped SGBN (2003)

Summary form only given. We present the first demonstration of single-mode buried channel waveguide lasers in neodymium-doped SGBN glass by a combination of direct bonding and direct UV writing techniques. Based on intersubstrate ion-exchange between specifically designed glass substrate materials we have used direct bonding to provide a region of atomic contact between Nd:SGBN and a potassium-rich borosilicate cladding substrate, between which K/sup +/-Na/sup +/ ion-exchange can occur. By taking this approach we have achieved a low-loss buried planar waveguide layer in the Nd:SGBN glass, which retains the photosensitive characteristics of the bulk material and into which single-mode channel waveguide structures can be directly written using a focussed UV beam. For this initial demonstration, a Nd:SGBN substrate containing SiO/sub 2/ (60 wt.%), GeO/sub 2/ (10 wt.%), B/sub 2/O/sub 3/ (10 wt.%), Na/sub 2/O (19 wt.%), and Nd/sub 2/O/sub 3/ (1 wt.%), was prepared and direct-bonded to a potassium-rich glass of similar composition to BK-7. Characterization of the 7.5-mm-long buried channel laser waveguide device was performed using a Ti:sapphire laser operating at 808 nm. The resultant 1059 nm laser output exhibited milliwatt-order laser thresholds, single-mode operation, propagation losses of <0.3 dB cm/sup -1/, and a maximum output power of 2 mW for 32 mW of absorbed pump power. These initial results demonstrate that optimisation of glass composition and direct UV writing parameters could lead to efficient low-loss buried waveguide devices in versatile bulk multicomponent oxide glasses for use with integrated optics.
Inhibition of the p38 Kinase Suppresses the Proliferation of Human ER-Negative Breast Cancer Cells (2009)

p38 kinases are members of the mitogen-activated protein kinase family that transduce signals from various environmental stresses, growth factors, and steroid hormones. p38 is highly expressed in aggressive and invasive breast cancers. Increased levels of activated p38 are markers of poor prognosis. In this study, we tested the hypothesis that blockade of p38 signaling would inhibit breast cancer cell proliferation. We studied breast cancer cell proliferation and cell cycle regulation upon p38 blockade by using three independent approaches: dominant-negative (DN) constructs, small interfering RNA (siRNA), and small molecule inhibitors. p38alpha and p38delta are the most abundant isoforms expressed by all examined human breast tumors and breast cancer cell lines. Expression of a DN p38 inhibited both anchorage-dependent and -independent proliferation of MDA-MB-468 cells. Silencing of p38alpha, but not p38delta, using siRNA suppressed MDA-MB-468 cell proliferation. Pharmacologic inhibitors of p38 significantly inhibited the proliferation of p53 mutant and ER-negative breast cancer cells. Whereas p38 has previously been considered as a mediator of stress-induced apoptosis, we propose that p38 may have dual activities regulating survival and proliferation depending on the expression of p53. Our data suggest that p38 mediates the proliferation signal in breast cancer cells expressing mutant but not wild-type p53. Because most ER-negative breast tumors express mutant p53, our results provide the foundation for future development of p38 inhibitors to target p38 for the treatment of p53 mutant and ER-negative breast cancers.
Merging Reality and Virtuality with Microsoft HoloLens (2015)

In this thesis, I will investigate the discursive framing of the HoloLens as a technology that is able to symbiotically merge reality and virtuality, and its relation with the HoloLens’ technological imaginary. I mean to answer the following research question using an adaptation of Fairclough’s ‘three- dimensional framework’ for doing critical discourse analysis: “How is the HoloLens discursively framed as a technology that is able to deliver a symbiotic mergence between reality and virtuality?” This thesis includes a threefold analysis. First, on the level of ‘text’ I will analyse how Microsoft discursively frames the HoloLens on their official HoloLens webpage as a technology that is able to symbiotically merge reality and virtuality. Second, on the level of ‘discursive practice’ I will analyse how technology review websites subsequently interpret Microsoft’s specific discursive framing of the HoloLens, and explain how both Microsoft and technology review websites together provide recourses that help to feed and frame the HoloLens’ technological imaginary. And third, on the level of ‘social practice’, I will analyse how in a dialectical sense, the HoloLens’ technological imaginary helps to constitute the discursive framing of the HoloLens, and how the HoloLens’ technological imaginary is in turn partially constituted by the discursive framing of the HoloLens.
Research Directions on the Role and Impact of ICT in Microfinance (2010)

Information and communication technology (ICT) is an important driver in the microfinance industry. Microfinance providers, both non-profit microfinance institutions (MFIs) and for-profit banks, provide financial services to the poor, and are critical for economic development in developing nations. As the industry matures, MFIs face a competitive environment, forcing them to balance the goals of outreach and sustainability. ICT may be the instigator of this new environment and the potential solution to MFI survivability. We propose research directions on the role and impact of ICT in the microfinance industry, using a microfinance technology and stakeholder ecosystem framework. This research is at the intersection of inquiry on ICT for development and the digital divide, the impact of microfinance, and the use of ICT in the financial services industry. We discuss the role and impact of ICT at the customer, the microfinance institution, donor, and industry levels.
A high-speed, AII-MOS, successive-approximation weighted capacitor A/D conversion technique (1975)

An N-channel all-MOS A/D converter, which utilizes charge redistribution on an array of binary-weighted capacitors to achieve a successive-approximation conversion in 20μs, will be described.
Reversible redox chemistry of quinones: Impact on biogeochemical cycles (2009)

The role of quinone biomolecules and quinone moieties of natural organic matter (NOM) as the electron transfer mediator in essential biogeochemical processes such as iron bioreduction and contaminant degradation has received considerable interests in the past decade. Hypothesized electron shuttling mechanism must be evaluated based on the availability and stability of quinones under a given environmental setting. The goal of this review is to examine the source, reactivity, and fate of potential quinone catalysts with respect to chemical interactions (e.g., with other quinones and nucleophiles) that will inevitably occur in complex environmental media. We will first discuss natural and anthropogenic sources of quinones in aqueous environments, and fundamental transformation pathways including cross reaction, autoxidation, and addition reactions. We will then assess how the described sources (molecular structure) and transformation pathways (stability) will impact the ability of a quinone molecule to catalyze a biogeochemical process. Thermodynamics and kinetics of electron transfer reactions with both the electron donor (e.g., hydrogen sulfide as a bulk reductant) and the terminal electron acceptor (e.g., nitroaromatic explosives in contaminant degradation), and stability towards irreversible side reactions are the key factors determining the geochemical conditions under which the catalysis by a quinone molecule will be operative.
Renewable Resources for the Production of Fuels and Chemicals (1976)

Fossil resources can be conserved by the use of renewable resources, primarily wood, either for the generation of energy or by the production of synthetic polymers using renewable materials as feedstocks. The sources of renewable resources for energy generation are summarized. The forms of energy generation possible from biomass are discussed. The production of chemicals and polymers from biomass is somewhat limited but still of conservation value. The chemical and by-product potential of renewable resources is evaluated. Production of chemicals by gasification is also briefly considered. (JSR)
Antioxidant Activity of Hydroxytyrosol Acetate Compared with That of Other Olive Oil Polyphenols (2001)

Hydroxytyrosol acetate was synthesized, and the antioxidant activity of this olive oil component was assessed in comparison with that of other olive oil components, namely hydroxytyrosol, oleuropein, 3,4-DHPEA-EA, and alpha-tocopherol in bulk oil and oil-in-water emulsions. The activity of the compounds was also assessed by scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol, oleuropein, or 3,4-DHPEA-EA but it had a radical scavenging activity similar to that of alpha-tocopherol. In oil, the antioxidant activity of hydroxytyrosol acetate was much higher than that of alpha-tocopherol or oleuropein, but in an emulsion 3,4-DHPEA-EA and alpha-tocopherol were more effective as antioxidants than hydroxytyrosol acetate. The antioxidant activity of hydroxytyrosol acetate was rather similar to that of hydroxytyrosol in oil and emulsions despite the difference in DPPH radical scavenging activity.
Porphyrins with Exocyclic Rings. 14.<sup>1</sup> Synthesis of Tetraacenaphthoporphyrins, a New Family of Highly Conjugated Porphyrins with Record-Breaking Long-Wavelength Electronic Absorptions (2000)

The Soret band for porphyrins is usually observed in the near-ultraviolet at approximately 400 nm, and few examples of "nonexpanded" porphyrins with this major absorption band at values above 500 nm have previously been reported in the literature. Ring fusion with aromatic ring systems such as naphthalene, anthracene, or phenanthrene generally only produces minor bathochromic shifts to this diagnostic absorption band. In this paper, the synthesis of a series of tetraacenaphthoporphyrins and their metal chelates is reported. The compact nature of the acenaphthylene ring system allows the introduction of meso substituents using the Lindsey methodology. meso-Tetraphenylporphyrin 10a shows the presence of a Soret band at 556 nm, while p-methoxy and p-nitro substituents in 10f and 10g, respectively, further shift this band to 560 and 570 nm. Addition of TFA produces the corresponding dications with slightly higher wavelength Soret bands at 565, 573, and 588 nm. These values compare to 525 nm for the dication of tetraacenaphthylene 8, which lacks the meso-aryl substituents, indicating that steric crowding and its resulting distortion of the macrocyclic conformation is responsible for a significant albeit minor portion of these shifts. The nickel(II), copper(II), and zinc chelates of 10a produce Soret bands at 528, 545, and 558 nm, respectively, demonstrating that the trend for increasing red shifts in metalloporphyrins across the periodic table is retained for this series. The lead(II) chelate 19d gave an additional "hyper" shift that brought the Soret band to 604 nm. A similar red shift could be achieved by introducing four phenylethynyl substituents at the meso positions, and this highly conjugated porphyrin (20) also showed a Soret band at 604 nm, while the corresponding dication afforded this absorption band at 629 nm. The essentially additive "hyper" shift due to lead chelation brought the Soret band for the related lead(II) complex 22d to 642 nm. These effects are by far the largest ever observed for true porphyrins and demonstrate that the Soret band can be fined tuned to virtually any part of the visible spectrum.
Using Sensor Information to Reduce the Carbon Footprint of Perishable Goods (2009)

Sensors enhance the control of perishable goods. New applications not only help to increase profits but also to reduce greenhouse gas emissions. An abatement cost analysis examines the trade-offs between profit maximization and emission minimization.
Blood-Based Biomarkers for Predicting the Risk for Five-Year Incident Coronary Heart Disease in the Framingham Heart Study via Machine Learning (2018)

An improved approach for predicting the risk for incident coronary heart disease (CHD) could lead to substantial improvements in cardiovascular health. Previously, we have shown that genetic and epigenetic loci could predict CHD status more sensitively than conventional risk factors. Herein, we examine whether similar machine learning approaches could be used to develop a similar panel for predicting incident CHD. Training and test sets consisted of 1180 and 524 individuals, respectively. Data mining techniques were employed to mine for predictive biosignatures in the training set. An ensemble of Random Forest models consisting of four genetic and four epigenetic loci was trained on the training set and subsequently evaluated on the test set. The test sensitivity and specificity were 0.70 and 0.74, respectively. In contrast, the Framingham risk score and atherosclerotic cardiovascular disease (ASCVD) risk estimator performed with test sensitivities of 0.20 and 0.38, respectively. Notably, the integrated genetic-epigenetic model predicted risk better for both genders and very well in the three-year risk prediction window. We describe a novel DNA-based precision medicine tool capable of capturing the complex genetic and environmental relationships that contribute to the risk of CHD, and being mapped to actionable risk factors that may be leveraged to guide risk modification efforts.
Experiences with the new FMI Standard Selected Applications at Dresden University (2011)

This paper describes how the new FMI standard is used at Dresden University to provide a universal model exchange. By employing the new standard exchange format a single simulation model can be used for different purposes in different software tools. Specific applications and their advantages will be presented as well as the development effort for their realisation. Special attention is paid to how FMI enables SimulationX models to be run in an interactive simulation on a motion platform. Finally, the benefits and drawbacks of the FMI interface are discussed from a user's perspective.
A Discussion of Hemoglobinuria and Hematuria (1955)

Hemoglobinuria may be defined as the symptom of a pathological state in which the animal passes hemoglobin in the urine. In this condition the urine will be pink to brownish-red in color depending upon the amount of hemoglobin passed.
Computer aided diagnosis of osteoporosis using multi-slice CT images (2010)

The patients of osteoporosis comprised about 11 million people in Japan and it is one of the problems the aging society has. In order to prevent the osteoporosis, it is necessary to do early detection and treatment. The development of Multislice CT technology made it possible to perform the three dimensional (3-D) image analysis with higher body axis resolution and shorter scan time. The 3-D image analysis using multi-slice CT images of thoracic vertebra can be used as a support to diagnose osteoporosis and at the same time can be used for lung cancer screening which may lead to its early detection. We develop an automatic extraction algorithm of vertebra, and the analysis algorithm of the vertebral body using shape analysis and a bone density measurement for the computer aided diagnosis of osteoporosis.
Monoclonal antibodies to two epitopes of beta-human chorionic gonadotropin for the treatment of cancer. (2003)

Human chorionic gonadotropin (hCG) is expressed by many histological types of cancer and may play an important role in tumor maintenance and progression. Vaccination of patients with the therapeutic peptide Avicine (CTP37; AVI BioPharma Inc/SuperGen Inc), that contains 37 amino acids from the carboxyl terminus (CTP37; AVI BioPharma Inc/SuperGen Inc) of hCG, can result in two distinct antibody responses to separate epitopes within the peptide. Colorectal cancer patients who develop both anti-hCG responses show a significant improvement in median survival time. These observations provide a compelling rationale for the development of two human monoclonal antibodies (mAbs), one for each of the epitopes within the 37 amino acid peptide region of hCG. Two such human mAbs, both exhibiting a high degree of specificity and affinity have been prepared using XenoMouse technology. These mAbs may prove useful in multiple clinical settings for the treatment of various cancers. Treatment options may include passive immunotherapy with both mAbs, mixed passive supplement to active specific immunotherapy with Avicine and conjugation of the mAbs with radioisotopes or cytotoxic drugs. The requirement for dual mAb therapy is consistent with current trends in the development of complex, non-toxic therapies for cancer.
Assessing Fit of Nontraditional Assistive Technologies (2010)

There is a variety of brain-based interface methods which depend on measuring small changes in brain signals or properties. These methods have typically been used for nontraditional assistive technology applications. Non-traditional assistive technology is generally targeted for users with severe motor disabilities which may last long-term due to illness or injury or short-term due to situational disabilities. Control of a nontraditional assistive technology can vary widely across users depending upon many factors ranging from health to experience. Unfortunately, there is no systematic method for assessing usability of nontraditional assistive technologies to achieve the best control. The current methods to accommodate users through trial-and-error result in the loss of valuable time and resources as users sometimes have diminishing abilities or suffer from terminal illnesses. This work describes a methodology for objectively measuring an individual’s ability to control a specific nontraditional assistive technology, thus expediting the technology-fit process.
Basic Amino Acids Predominate in the Sequential Autoantigenic Determinants of the Small Nuclear 70K Ribonucleoprotein (1994)

Autoantibodies binding the 70K nRNP polypeptide are commonly found in the serum of patients with systemic lupus erythematosus. IgG antibodies binding overlapping octapeptides of 70K nRNP have been evaluated in 10 patients with anti-nRNP precipitins, seven patients with other autoimmune serology, and four normal human sera. Neither normal controls nor patients without an anti-nRNP precipitin significantly bind any of the 70K nRNP octapeptides. Sera containing an anti-nRNP precipitin strongly bind various combinations of eleven different regions of the 70K nRNP protein. One antigenic region is consistently the most reactive in nine of ten nRNP precipitin positive sera tested. This sequence, KDKDRDRKRRSSRSR, is highly charged and has a similar pattern of alternating basic amino acids also present in seven of the other purported humoral autoimmune epitopes of the 70K nRNP polypeptide. The closely related DRKR and ERKR are important components of two of these epitopes. All regions of the 70K peptide bound by human anti-nRNP precipitin positive sera are very rich in the basic amino acids, especially lysine (chi-square = 23.03, odds ratio = 13.3, P < 0.000001).
Management of Severe Ulcer Rebleeding (1999)

The number of patients hospitalized for upper gastrointestinal bleeding from ulcers has decreased substantially in recent years. The decrease reflects a variety of factors: the widespread use of histamine H2–receptor blockers and proton-pump inhibitors, the eradication of Helicobacter pylori in patients with ulcers, and increased awareness among patients with ulcers of the potential dangers of taking nonsteroidal antiinflammatory drugs. Nonetheless, severe upper gastrointestinal bleeding remains a common medical emergency.1 In the past two decades, the responsibility for the initial diagnosis and treatment of gastrointestinal bleeding has shifted in most medical centers from general surgeons and radiologists to gastrointestinal . . .