gebhart/patrepeval huggingface dataset:
Maintenance of balance, gait patterns, and obstacle clearance in Alzheimer's disease (1995)

Patients with cognitive impairment, particularly as a result of Alzheimer's disease (AD), are at increased risk for falls, but it is unclear how, or if, they differ from normal adults in their balance, gait, or ability to clear an obstacle in their path. Using an optoelectronic camera system, we compared body motions and force output at the feet in patients with probable AD (n = 17) with those in healthy older adults (n = 15) while they stood on a force plate or on a beam attached to the force plate that was either stationary or accelerating. Using the same camera system and comparing this AD group with another group of healthy older adults (n = 24), we observed the AD patients during normal walking and while clearing 25- and 152-mm-high obstacles. None of the AD patients had extrapyramidal signs or musculoskeletal impairments. Compared with healthy older adults, normal walking speed was significantly slower in the AD group (p < 0.0001). While clearing either obstacle, the AD patients were significantly slower in their approach (p < 0.0001) and crossing (p < 0.0001) speeds and landed closer to the obstacle after having crossed it (p < 0.02). Moreover, the percent of trials in which a subject made contact with an obstacle was significantly higher in patients with AD (p < 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)
<i>In situ</i> texture monitoring for growth of oriented cubic boron nitride films (1999)

We report evidence for oriented growth of pure-phase cubic boron nitride on silicon (100) substrates. The films are deposited at high temperatures (up to 1200 °C) by reduced-bias ion-assisted sputtering. The growth technique produces highly textured c-BN films with relatively large grain size (∼1000 Å) and reduced residual stress as the bias voltage is decreased. We have been able to grow thick (up to 2 μm) cubic boron nitride films containing 100% of the cubic phase with the (001) crystallographic axis of c-BN oriented perpendicular to the surface of the film. We show how reflection high-energy electron diffraction applied to texture monitoring in polycrystalline films can be used as an in situ process control technique that allows texture identification and quantitative characterization of its angular spread.
Security Analysis of x86 Processor Microcode (2014)

Modern computer processors contain an embedded rmware known as microcode that controls decode and execution of x86 instructions. Despite being proprietary and relatively obscure, this microcode can be updated using binaries released by hardware manufacturers to correct processor logic aws (errata). In this paper, we show that a malicious microcode update can potentially implement a new malicious instructions or alter the functionality of existing instructions, including processor-accelerated virtualization or cryptographic primitives. Not only is this attack vector capable of subverting all software-enforced security policies and access controls, but it also leaves behind no postmortem forensic evidence due to the volatile nature of write-only patch memory embedded within the processor. Although supervisor privileges (ring zero) are required to update processor microcode, this attack cannot be easily mitigated due to the implementation of microcode update functionality within processor silicon. Additionally, we reveal the microarchitecture and mechanism of microcode updates, present a security analysis of this attack vector, and provide some mitigation suggestions. A tool for parsing microcode updates has been made open source, in conjunction with a listing of our dataset.
Total Neoadjuvant Therapy With FOLFIRINOX Followed by Individualized Chemoradiotherapy for Borderline Resectable Pancreatic Adenocarcinoma (2018)

ClinicalTrials.gov Identifier: NCT01591733.
A robot in the kitchen (2010)

Rosie, the robot who kept house for the title family in "The Jetsons," a 1960s animated television show, has at last come alive-sort of. Before you'll see a robot slicing cucumbers in your kitchen, researchers will need to make these mechanical servants smarter. Here's how three teams are tackling this challenge.
Private Editing Using Untrusted Cloud Services (2011)

We present a general methodology for protecting the confidentiality and integrity of user data for a class of on-line editing applications. The key insight is that many of these applications are designed to perform most of their data-dependent computation on the client side, so it is possible to maintain their functionality while only exposing an encrypted version of the document to the server. We apply our methodology to Google Documents and describe a prototype extension tool that enables users to use a cloud application to manage their documents without sacrificing confidentiality or integrity. To provide adequate performance, we employ an incremental encryption scheme and extend it to support variable-length blocks. We analyze the security of our scheme and report on experiments that show our extension preserves most of the cloud application's functionality with less than 10% overhead for typical use.
Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease (2008)

Reductions in total Bifidobacterium and B. longum populations were associated with both active and non-active CD when compared to controls. These bacterial groups could constitute novel targets for adjuvant dietary therapies although the confirmation of this hypothesis would require further investigations.
Integration of a CAN-based connection-oriented communication model into Real-Time CORBA (2004)

The Real-Time CORBA and minimumCORBA specifications are important steps towards defining standard-based middleware which can satisfy real-time requirements in an embedded system. These requirements can only be fulfilled if the middleware utilizes the features of a real-time network. The controller area network (CAN) is one of the most important networks in the field of real-time embedded systems. Consequently, this paper presents a CAN-based connection-oriented point-to-point communication model and its integration into Real-Time CORBA. In order to make efficient use of the advantages of CAN, we present an inter-ORB protocol, which uses smaller message headers for CAN and maps the CAN priorities to a band of CORBA priorities. We also present design and implementation details with some preliminary performance results.
Interpenetrating Polymer Networks Based on SBR/PS. 1. Control of Morphology by Level of Cross-Linking (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInterpenetrating Polymer Networks Based on SBR/PS. 1. Control of Morphology by Level of Cross-LinkingA. A. Donatelli, L. H. Sperling, and D. A. ThomasCite this: Macromolecules 1976, 9, 4, 671–675Publication Date (Print):July 1, 1976Publication History Published online1 May 2002Published inissue 1 July 1976https://pubs.acs.org/doi/10.1021/ma60052a029https://doi.org/10.1021/ma60052a029research-articleACS PublicationsRequest reuse permissionsArticle Views522Altmetric-Citations117LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Educational Leadership: A Strategic Co‐operative Japanese Corporate Model (1993)

Provides a unique model for strategic, co‐operative international management education. Describes multi‐educational programme modules which incorporate cross‐cultural, language and technology training.
The Research of Regional Collaborative Innovation Mode in China: Based on Principal Component Analysis (2012)

The research on regional innovation is fully developed by many researchers for these thirty years. We can found from prior researches that regional innovation subjects are the enterprise, universities, research institutions, government and intermediary organizations, and each has different functions and effects. But previous quantitative researches are mostly focused on regional innovation environment, innovation ability and the relationship between some factors and regional innovation ability, the qualitative researches about behaviors of innovation subjects is lack. So this paper will apply the principal component analysis and point out what is the mode in each region in China. This paper will supply other researchers a new method to analysis regional innovation. This paper divided into six parts: Introduction, Related researches, Index selection, Empirical research, Conclusion, Limitations. Key words: Regional innovation subjects; Collaborative innovation; Principal component analysis; Regional innovation mode
Removing the bias from line detection (2002)

The extraction of curvilinear structures is an important low-level operation in computer vision. Most existing operators use a simple model for the line that is to be extracted, i.e., they do not take into account the surroundings of a line. Therefore, they will estimate a wrong line position whenever a line with different lateral contrast is extracted. In contrast, the algorithm proposed in this paper uses an explicit model for lines and their surroundings. By analyzing the scale-space behavior of a model line profile, it is shown how the bias that is induced by asymmetrical lines can be removed. Thus, the algorithm is able to extract an unbiased line position and width, both with sub-pixel accuracy.
Biometric identification using driving behavioral signals (2005)

We investigate the uniqueness of driver behavior in vehicles and the possibility of using it for personal identification with the objectives of achieving safer driving, of assisting the driver in case of emergencies, and of being a part of a multi-mode biometric signature for driver identification. We use Gaussian mixture models (GMM) for modeling the individualities of the accelerator and brake pedal pressures, and focus on not only the static features, but also the dynamics of the pedal pressures. Experimental results show that the dynamic features significantly improve the performance of driver identification.
Eigen Decomposition-Based Hybrid Precoding for Millimeter Wave MIMO Systems With Low-Resolution ADCs/DACs (2019)

In millimeter wave multiple-input multiple-output (MIMO) systems, the hybrid beamforming architecture has been put forward to reduce the high hardware cost and power consumption, which are resulted from the tremendous requirements of dedicated radio frequency (RF) chain. In this paper, it aims at to design analog and digital precoders for a hybrid architecture with low-resolution digital to analog converter (DAC) transmitters and low-resolution analog to digital converter (ADC) receivers. In order to reap the large channel gain, the alternating projection method is employed to develop the analog precoder. Meanwhile, the digital precoder is designed via sub-rate successive maximization algorithm based on eigen decomposition (ED) to maximize the achievable rate. Simulation results demonstrate that the proposed ED-based hybrid precoding outperforms the orthogonal matching pursuit (OMP) based precoding and can achieve a performance comparable to the optimal digital precoding with infinite resolution in low signal-to-noise ratio (SNR) regime. Furthermore, the achievable rate of proposed ED-based hybrid precoding is illustrated to close to the optimal precoding as the quantization bits increases, in low-to-medium SNR range.
Impact of myocardial haemorrhage on left ventricular function and remodelling in patients with reperfused acute myocardial infarction (2009)

Myocardial haemorrhage, the presence of which can easily be detected with T2-weighted MRI, is a frequent complication after successful myocardial reperfusion and an independent predictor of adverse LV remodelling regardless of the initial infarct size.
Service-oriented power management for an integrated multi-function home server (2007)

A home server usually is an integrated system of communication, broadcast, game, media center, and home automation. It is a kind of a multi-function all-in-one system. The home server should be turned on for all day long because it plays a role of network hub, multimedia contents server, and home automation controller. Therefore it is necessary to reduce its power consumption to lower the operational cost. To achieve this power reduction, this paper proposes service-oriented power management method for an integrated multi-function home server. This method classifies the resources of the home server into small functional blocks according to the kind of service and turns on only the resources needed for the requested services. When a new service is requested only necessary resources are turned on. And when a service exit occurs, unnecessary resources are turned off. This power management greatly reduces a waste of power dissipation. We also present some scenarios utilizing this
Black ginseng activates Akt signaling, thereby enhancing myoblast differentiation and myotube growth (2017)

BG enhances myoblast differentiation and myotube hypertrophy by activating Akt/mTOR/p70S6k axis. Thus, our study demonstrates that BG has promising potential to treat or prevent muscle loss related to aging or other pathological conditions, such as diabetes.
Differences in bone and vitamin D metabolism between primary hyperparathyroidism and malignancy-associated hypercalcemia. (1996)

Bone and vitamin D metabolism are examined in patients with primary hyperparathyroidism (1 degree HPT), humoral hypercalcemia of malignancy (HHM), and local osteolytic hypercalcemia (LOH) with normal renal function. Among the bone resorption markers, T scores of total deoxypyridinoline (Dpyd) were highest in HHM and were significantly higher than those in 1 degree HPT. Among the formation markers, T scores of osteocalcin (OC) were highest in 1 degree HPT but were negative in HHM. The elevation in total Dpyd was associated with an increase in OC in 1 degree HPT, and the ratios of total Dpyd/OC were similar to those in controls. In contrast, many patients with HHM and LOH exhibited elevated total Dpyd and suppressed OC with increased total Dpyd/OC ratios, but the ratios varied widely. Serum 1,25-dihydroxyvitamin D [1,25(OH)2D] was elevated in 1 degrees HPT but was suppressed in HHM and LOH at any serum Ca levels. These results demonstrate that increased bone resorption is associated with enhanced bone formation in 1 degrees HPT but are uncoupled in many of the HHM and LOH patients, and that total Dpyd/OC ratio can be a useful index to estimate the coupling state of bone. It is suggested that the reduction in serum 1,25(OH)2D cannot be explained by an elevation in serum Ca in HHM and LOH, and that the differences in bone and vitamin D metabolism in HHM and LOH from those in 1 degree HPT may be caused by a common mechanism such as the secretion of some cytokines from tumors.
Narrow-spectral-linewidth silicon photonic wavelength-tunable laser with highly asymmetric Mach–Zehnder interferometer (2015)

We propose a narrow-spectral-linewidth silicon photonic wavelength-tunable laser with a novel external wavelength-tunable filter, which consists of two silicon ring resonators with different circumferences and a highly asymmetric Mach-Zehnder interferometer (MZI), the two optical paths of which have significantly different lengths. Calculations and experimental results indicated that the gain difference between longitudinal modes was increased by the highly asymmetric MZI. Consequently, a narrow spectral linewidth of 12 kHz and a stable single-mode oscillation were obtained.
Functional analysis of <i>O</i>‐linked oligosaccharides in threonine/serine‐rich region of <i>Aspergillus</i> glucoamylase by expression in mannosyltransferase‐disruptants of yeast (1999)

The glaA gene encoding glucoamylase I (GAI) of Aspergillus awamori var. kawachi was heterologously expressed in mannosyltransferase mutants of Saccharomyces cerevisiae, in which the pmt1 gene and the kre2 gene were disrupted. The GAI enzymes expressed in these yeast mutant cells exhibited a lesser extent of O-glycosylation. Secretion of GAI expressed in the pmt1-disruptant and in the kre2-disruptant, respectively, was almost the same as that of GAI expressed in wild type (wt) strains. The number of O-linked mannose in GAI from wt yeast strain ranged in size from one (Man1) to five (Man5). On the other hand, the O-linked oligosaccharides of GAI from the pmt1-disruptant ranged in size from Man1 to Man4. Man5 was not detected and Man2-Man4 were reduced in proportion to the reduction of Man1. The O-linked oligosaccharides of GAI from the kre2-disruptant ranged from Man1 to Man4, and the molar amount of Man4 was reduced to 27.3%, compared to that of the wt strain. The hydrolyzing abilities for soluble starch and the adsorbing abilities on raw starch were comparable between both disruptants and wt strains. However, the digesting abilities for raw starch of the disruptants were decreased to 70% of those of the wt strains. Stabilities of GAI of the disruptants were reduced toward extreme pH and high temperature, compared to those of the wt strains. These results demonstrate that the O-linked oligosaccharides of GAI are responsible for the enzyme stability and activity toward insoluble substrates but not for secretion.
Wireless sensor networks for health monitoring (2005)

We propose a platform for health monitoring using wireless sensor networks. Our platform is a new architecture called CustoMed that will reduce the customization and reconfiguration time for medical systems that use reconfigurable embedded systems. This architecture is a network enabled system that supports various wearable sensors and contains on-board general computing capabilities for executing individually tailored event detection, alerts, and network communication with various medical informatics services. The customization of such system with a large number of "med nodes" is extremely fast even by non-engineering staff. In this paper, we present the architecture of such device along with experimental analysis that evaluates the performance of such system.
Seismic attenuation of Atlantic margin basalts: Observations and modeling (2006)

Abstract Paleogene basalts are present over much of the northeastern Atlantic European margin. In regions containing significant thicknesses of layered basalt flows, conducting seismic imaging within and beneath the volcanic section has proven difficult, largely because the basalts severely attenuate and scatter seismic energy. We use data from a vertical seismic profile (VSP) from well 164/07-1 that penetrated 1.2 km of basalt in the northern Rockall Trough west of Britain to measure the seismic attenuation caused by the in-situ basalts. The effective quality factor Qeff of the basalt layer is found from the VSP to be 15–35, which is considerably lower (more attenuative) than the intrinsic attenuation measured on basalt samples in the laboratory. We then run synthetic seismogram models to investigate the likely cause of the attenuation. Full waveform 1D modeling of stacked sequences of lava flows based on rock properties from the same well indicates that much of the seismic attenuation observed from the VSP can be accounted for by the scattering effects of multiple thin layers with high impedance contrasts. Phase-screen seismic modeling of the rugose basalt surface at the top-of-basalt sediment interface, with the magnitude and wavelength of the relief constrained by a 3D seismic survey around the well, suggests that surface scattering from this interface plays a much smaller role than internal scattering in attenuating the seismic signal as it passes through the basalt sequence.
CHAPTER X (2012)

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The Zero-Delay Wavenumber Spectrum Estimation for the Analysis of Array ECG Signals-An Alternative to Isopotential Mapping (1986)

The zero-delay wavenumber spectrum (ZDWS) estimation approach is proposed for the analysis of array ECG signals as an alternative to isopotential mapping (IM). The ZDWS approach is advantageous because the key parameters related to cardiac electrical activation can be easily identified in the frequency-wavenumber domain. The method explains the data as the sum of wide-band planewaves projected onto the array plane and provides an accurate estimate of their number and bearing. The slowness distribution of each of the planewaves is then obtained by estimating their temporal spectrum. Simulated data and experimental ECG data collected from a canine epicardial preparation during control and localized myocardial ischemic condition'are analyzed via the ZDWS and IM. It is demonstrated that the ZDWS methodology provides a means for an objective, robust, and repetitive characterization of the array data which can explain the modulation in the cardiac activation wavefront produced by an area of localized coronary artery occlusion.
Nephrin missense mutations: induction of endoplasmic reticulum stress and cell surface rescue by reduction in chaperone interactions (2013)

Nephrin, an important component of the podocyte filtration slit diaphragm, plays a key role in the maintenance of glomerular permselectivity. Mutations in nephrin lead to proteinuria and congenital nephrotic syndrome. Nephrin undergoes posttranslational modifications in the endoplasmic reticulum (ER) prior to export to the plasma membrane. We examined the effects of human nephrin disease-associated missense mutations on nephrin folding in the ER and on cellular trafficking in cultured cells. Compared with wild-type (WT) nephrin, the mutants showed impaired glycosylation and enhanced association with the ER chaperone, calnexin, as well as accumulation in the ER. Nephrin mutants demonstrated enhanced ubiquitination, and they underwent ER-associated degradation. Certain nephrin mutants did not traffic to the plasma membrane. Expression of nephrin mutants resulted in the stimulation of the activating transcription factor-6 pathway of the unfolded protein response, and an increase in the ER chaperone, Grp94. We treated cells with castanospermine (an inhibitor of glucosidase I) in order to decrease the association of nephrin mutants with calnexin. Castanospermine increased plasma membrane expression of nephrin mutants; however, full glycosylation and signaling activity of the mutants were not restored. Modulation of ER quality control mechanisms represents a potential new approach to development of therapies for proteinuric kidney disease, including congenital nephrotic syndrome.
Atlas of Synovial Fluid Cytopathology (1991)

Like all specialized areas of medicine, that of joint disease informative. The techniques, practical and interpretive, has become surrounded by a practical mystique and are highly reproducible and sim