gebhart/patrepeval huggingface dataset:
Global Synchronization for Discrete-Time Stochastic Complex Networks With Randomly Occurred Nonlinearities and Mixed Time Delays (2009)

In this paper, the problem of stochastic synchronization analysis is investigated for a new array of coupled discrete-time stochastic complex networks with randomly occurred nonlinearities (RONs) and time delays. The discrete-time complex networks under consideration are subject to: 1) stochastic nonlinearities that occur according to the Bernoulli distributed white noise sequences; 2) stochastic disturbances that enter the coupling term, the delayed coupling term as well as the overall network; and 3) time delays that include both the discrete and distributed ones. Note that the newly introduced RONs and the multiple stochastic disturbances can better reflect the dynamical behaviors of coupled complex networks whose information transmission process is affected by a noisy environment (e.g., internet-based control systems). By constructing a novel Lyapunov-like matrix functional, the idea of delay fractioning is applied to deal with the addressed synchronization analysis problem. By employing a combination of the linear matrix inequality (LMI) techniques, the free-weighting matrix method and stochastic analysis theories, several delay-dependent sufficient conditions are obtained which ensure the asymptotic synchronization in the mean square sense for the discrete-time stochastic complex networks with time delays. The criteria derived are characterized in terms of LMIs whose solution can be solved by utilizing the standard numerical software. A simulation example is presented to show the effectiveness and applicability of the proposed results.
DISCUSSION. REDEVELOPMENT OF THE AIRPORT AT NEWCASTLE-UPON TYNE. (1971)

Keywords REDEVELOPMENT, PASSENGERS, FORECASTS, THICKNESS, BEARING, PROCEDURE, AIRPORTS, PAVEMENTS, CALIFORNIA, DESIGN NEWCASTLE UK... Show All
Transoral laser microsurgery for recurrent laryngeal carcinoma after primary treatment: A systematic review and meta-analysis (2015)

It seems that TLM is an effective option for recurrent laryngeal cancer with regard to the high incidence of OS, local control, and especially organ preservation. However, more prospective studies are needed to confirm its efficiency.
Guide for Design and Construction of Concrete Parking Lots (1987)

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NMR Structures Reveal How Oxidation Inactivates Thrombomodulin (2003)

Oxidation of Met 388, one of the three linker residues connecting the fourth and fifth EGF-like domains of thrombomodulin (TM), is deleterious for TM activity. An NMR structure of the smallest active fragment of TM (TMEGF45) and a crystal structure of a larger fragment (TMEGF456) bound to thrombin both show that Met 388 is packed into the fifth domain. Using multidimensional NMR, we have solved the structure of TMEGF45 in which Met 388 is oxidized (TMEGF45ox) and the structure of TMEGF45 in which Met 388 is mutated to Leu (TMEGF45ML). Comparison of the structures shows that the fifth domain has a somewhat different structure depending on the residue at position 388, and several of the thrombin-binding residues are packed into the fifth domain in the oxidized protein while they are exposed and free to interact with thrombin in the native structure and the Met-Leu mutant. This observation is consistent with kinetic measurements showing that the K(m) for TMEGF45ox binding to thrombin is 3.3-fold higher than for the native protein. Most importantly, the connection between the two domains, as indicated by interdomain NOEs, appears to be essential for activity. In the TMEGF45ox structure which has a reduced k(cat) for protein C activation by the thrombin-TMEGF45ox complex, interaction between the two domains is lost. Conversely, a tighter connection is observed between the two domains in TMEGF45ML, which has a higher k(cat) for protein C activation by the thrombin-TMEGF45ML complex.
Self-Supported Pd<sub><i>x</i></sub>Bi Catalysts for the Electrooxidation of Glycerol in Alkaline Media (2014)

Highly active self-supported PdxBi catalysts are synthesized by the sacrificial support method. Self-supported PdxBi catalysts have a porous nanostructured morphology with high surface areas (in the range from 75 to 100 m(2) g(-1)), making PdxBi a state-of-the-art catalyst. Pd4Bi displays the highest activity toward glycerol oxidation. In situ Fourier transform infrared spectroscopy highlights the unique catalytic behavior of self-supported PdxBi materials due to their particular structure and morphology. The confinement of reactants and intermediates in pores acting as nanoreactors is responsible for the high selectivity as a function of the electrode potential: aldehyde and ketone at low potentials, hydroxypyruvate at moderate potentials, and CO2 at high potentials. Moreover, the selectivity depends on the electrode history: it is different for the positive potential scan direction than for the reverse direction, where the catalyst becomes selective toward the production of carboxylates.
Studies on adhesive monomers for teeth. V. Influence of substituents in methacrylamide derivatives (1990)

Abstract In order to shed light on the relationship of monomer structure and adhesiveness to tooth enamel, methacrylamides having various substituents were synthesized and evaluated as dental adhesives. Among 17 methacrylamides synthesized here, those having N‐m ‐ and N‐p ‐carbethoxyphenyl, N‐p ‐fluorophenyl, and N ‐3‐carboxycyclohexyl groups showed adhesive tensile strength of more than 100 kg/cm 2 with minimal drops in strength on standing, indicating high potentials as novel adhesives. It was also confirmed that a carboxyl group enhances adhesive tensile strength peculiarly regardless of skeletal structures.
Tree rotations for improving bounding volume hierarchies (2008)

Current top-down algorithms for constructing bounding volume hierarchies (BVHs) using the surface area heuristic (SAH) rely on an estimate of the cost of the potential subtrees to determine how to partition the primitives. After a tree has been fully built, however, the true cost value at each node can be computed. We present two related algorithms that use this information to reduce the treepsilas total cost through a series of local adjustments (tree rotations) to its structure. The first algorithm uses a fast and simple hill climbing method and the second uses simulated annealing to obtain greater improvements by avoiding local minima. Both algorithms are easy to add to existing BVH implementations and are suitable for preprocessing static geometry for interactive ray tracing.
The design and performance evaluation of high-speed packet data MAC protocol for CDMA based IMT2000 (2003)

We propose and evaluate the performance of CDMA (code division multiple access) based high-speed packet data service MAC (medium access control) protocol for IMT2000 system. This proposed MAC supports a smooth evolution from the conventional IS-95 based system to IMT2000. Also, the proposed MAC supports connectionless packet transmission over wireless channels. Channel utilization is maximized by using discontinuous transmission mode technology and efficient channel re-use property. Most of all, a 5 ms-size message structure based control mechanism provides a fast MAC management scheme. Then a sleep-mode based physical channel control function is provided to support the power save effect and fast channel activation method. Also, channel related information is minimized by using the state transition characteristics of the proposed MAC. Especially, the proposed MAC is admitted by TR45.5 as a part of the cdmaOne standard, and proposed to ITU-R as a CDMA based IMT2000 radio transmission technology candidate.
PP.09.10 (2015)

Objective: Primary aldosteronism (PA) has been the most common secondary cause of hypertension. The present study investigated the difference of left ventricular Structure and function in hypertensive patients with primary aldosteronism and essential hypertension. Design and method: Hypertensive patients from the hypertension department or clinic in Ruijin hospital were studied. The sample included 100 patients with primary aldosteronism and 100 controls with essential hypertension matched for age, gender, and 24-hour ambulatory monitoring BP. Left ventricular mass index (LVMI), LA volume index (LAVI), Ejection fraction were calculated. LV diastolic function was estimated by the ratio of early diastolic velocities (E) from transmitral inflow to early diastolic velocities (E’) of tissue Doppler at mitral annulus. Results: Primary aldosteronism and essential hypertension patients had similar LV dimensions, LV wall thickness, LVMI and LV systolic function. PA patients were associated with greater impairment in diastolic function as reflected by E’ (5.8 ± 1.9 cm/s vs. 6.6 ± 2.1 cm/s, respectively; p = 0.004), E/E’ ratio (13.5 ± 4.3 vs. 11.9 ± 3.3, respectively; p = 0.005) and higher left atrial volume index (23.0 ± 5.8 ml/m2 vs. 21.1 ± 5.5 ml/m2, respectively; p = 0.02). Multivariate analysis showed that E/E’ ratio independently correlated with age (β = 0.457, p < 0.001) and serum potassium (β = −0.230, p = 0.018). The left ventricular geometric, systolic functional parameters and patterns of LV-hypertrophy were similar in male patients between PA and EHT groups. While in female patients, PA was correlated with higher LVMI (103 ± 24 g/m2 vs. 93 ± 18 g/m2, respectively; p = 0.04) and lower RWT (0.38 ± 0.05 vs. 0.42 ± 0.04, respectively; p = 0.001). Conclusions: The increase in aldosterone levels could contribute to the impairment of LV diastolic function in both sexes and higher prevalence of eccentric hypertrophy in women than in men. LV diastolic function independently correlated with age and serum potassium in PA.
Influence of hypertension on aortic atherosclerosis in the Watanabe rabbit. (1989)

The effects of one-kidney, one clip Goldblatt hypertension on aortic atherosclerosis have been studied in the Watanabe heritable hyperlipidemic (WHHL) rabbit. Renovascular surgery was performed on WHHL rabbits at 3 months of age, and the rabbits were followed for periods of 3-6 months. Aortic atherosclerosis was assessed by measurement of intimal surface involvement with atherosclerotic lesions, determination of aortic free and ester cholesterol content, and microscopic examination. Systolic blood pressure increased by approximately 40-60 mm Hg in the renovascular surgical group as compared with the sham-operated group, but body weight, heart rate, serum cholesterol, and serum triglyceride were unaffected. Aortic atherosclerosis was increased in the hypertensive rabbits, even after 2-3 months of hypertension. At 3 months after renovascular surgery, the aortic surface area covered by atherosclerotic disease averaged 77 +/- 4.4% in hypertensive as compared with 16 +/- 3.3 in control rabbits. At 6 months after surgery, the values were 62 +/- 8.2% and 30 +/- 5.3% in the hypertensive and control rabbits, respectively. The differences in surface involvement and cholesterol content as a result of hypertension were particularly prominent in the descending thoracic aorta. Atherosclerotic lesions in the descending thoracic and abdominal aortic regions of normotensive WHHL rabbits were localized primarily to the ostia of branch vessels, but in the hypertensive rabbits, the involvement was typically very diffuse. No major differences in the nature of atherosclerotic lesions of comparable size were apparent by light microscopy. The results indicate that hypertension accelerates atherogenesis in the WHHL rabbit and suggest that this model may be valuable for studying the mechanisms by which such acceleration is induced.
Testing PUF-based secure key storage circuits (2014)

Design for test is an integral part of any VLSI chip. However, for secure systems extra precautions have to be taken to prevent that the test circuitry could reveal secret information. This paper addresses secure test for Physical Unclonable Function based systems. In particular it provides the testability analysis and a secure Built-In Self-Test (BIST) solution for Fuzzy Extractor (FE) which is the main component of PUF-based systems. The scheme targets high stuck-at-fault (SAF) coverage by performing scan-chain free functional testing, to prevent scan-chain abuse for attacks. The scheme reuses existing FE sub-blocks (for pattern generation and compression) to minimize the area overhead. The scheme is integrated in FE design and simulated; the results show that a SAF fault coverage of 95.1% can be realized with no more than 50k clock cycles at the cost of a negligible area overhead of only 2.2%. Higher fault coverage is possible to realize at extra cost.
Chemosensitivity Determinants of Irinotecan Hydrochloride in Hepatocellular Carcinoma Cell Lines (2008)

Irinotecan hydrochloride (CPT-11) is an effective anticancer drug, and its metabolic pathway has been well studied. Nevertheless, in human hepatocellular carcinoma (HCC), its cytotoxicity is less well studied and the determination of its chemosensitivity is unclear. We, therefore, examined chemosensitivities of HCC cell lines for CPT-11 and SN-38, and mRNA expressions of several molecules in their metabolic pathway. Three markers were found to correlate well with chemosensitivity: breast cancer resistance protein (BCRP), cytochrome P450 (CYP) 3A4 and uridine diphosphate-glucuronosyl transferase (UGT) 1A1. Next, CYP3A4/UGT1A1/BCRP inhibitor naringenin and BCRP inhibitor elacridar were tested for enhancement of their chemosensitivity. Both of naringenin and elacridar separately enhanced the sensitivity for CPT-11 and SN-38 in KYN-2 cells abundantly expressing BCRP, CYP3A4/5 and UGT1A1, but not in KYN-1 cells expressing lower levels. However, naringenin had little effect on the sensitivity in JHH-4 and HLE cells with higher CYP3A4/5 and lower UGT1A1 and BCRP expression. On the other hand, naringenin and elacridar significantly increased the chemosensitivity for CPT-11 and SN-38 in the KYN-1-derived cells artificially overexpressing BCRP. Furthermore, flow cytometric analysis showed that naringenin raised intracellular accumulation of CPT-11 as well as elacridar. Those results suggest that BCRP is one of the chemosensitivity determinants of CPT-11 in HCC cells and its inhibition might be critical for cells expressing abundant BCRP.
From learning models of natural image patches to whole image restoration (2011)

Learning good image priors is of utmost importance for the study of vision, computer vision and image processing applications. Learning priors and optimizing over whole images can lead to tremendous computational challenges. In contrast, when we work with small image patches, it is possible to learn priors and perform patch restoration very efficiently. This raises three questions - do priors that give high likelihood to the data also lead to good performance in restoration? Can we use such patch based priors to restore a full image? Can we learn better patch priors? In this work we answer these questions. We compare the likelihood of several patch models and show that priors that give high likelihood to data perform better in patch restoration. Motivated by this result, we propose a generic framework which allows for whole image restoration using any patch based prior for which a MAP (or approximate MAP) estimate can be calculated. We show how to derive an appropriate cost function, how to optimize it and how to use it to restore whole images. Finally, we present a generic, surprisingly simple Gaussian Mixture prior, learned from a set of natural images. When used with the proposed framework, this Gaussian Mixture Model outperforms all other generic prior methods for image denoising, deblurring and inpainting.
Fundamental aspects of pulse phase-locked loop technology-based methods for measurement of ultrasonic velocity (1992)

A new instrument based on a constant frequency pulse phase-locked loop concept has been developed to accurately measure the ultrasonic phase velocity in condensed matter. Measurements of the sound velocity in ultrapure water are reported in which both damped and undamped transducers are used with the instrument together with reflectors of various thicknesses placed in the sound propagation path. An analysis of measurements made with the new instrument and similar measurements, taken under identical experimental conditions, using a popular variable frequency pulsed-phase-locked loop instrument is reported. Uncertainties in both measurement systems are analyzed and discussed. A method for measuring inherent phase shifts, not addressed by previous investigators, within the variable frequency pulsed phase-locked loop system and a derivation of the equations that govern the overall use of variable frequency systems using phase-sensitive comparisons are presented. The effects of a finite pulse length on the measurements of phase velocity in dispersive media are addressed in detail.
Flow in the Piston-Cylinder-Ring Crevices of a Spark-Ignition Engine: Effect on Hydrocarbon Emissions, Efficiency and Power (1982)

<div class="htmlview paragraph">The flow into and out of the piston top-land crevice of a spark-ignition engine has been studied, using a square-cross-section single-cylinder engine with two parallel quartz glass walls which permit optical access to the entire cylinder volume. Schlieren short-time exposure photographs and high speed movies were used to define the essential features of this flow.</div> <div class="htmlview paragraph">The top-land crevice and the regions behind and between the rings consist of volumes connected through the ring gaps. A system model of volumes and orifices was therefore developed and used to predict the flow into and out of the crevice regions between the piston, piston rings and cylinder wall.</div> <div class="htmlview paragraph">It was shown that two types of flow out of the top-land crevice entrance occur during the expansion stroke: (i) a low velocity flow which expands out of the crevice entrance, around the piston circumference, shortly after peak cylinder pressure occurs; (ii) a jet-type flow through the top piston-ring gap, later in the expansion process, which starts when the pressure above the ring gap falls below the pressure beneath the gap. Both these flows were observed when a production engine piston crown was inserted into the square-cross-section piston crown of the transparent engine facility in visualization experiments.</div> <div class="htmlview paragraph">The flow model was coupled with a ring motion model and applied to a real engine geometry. The model predicts the amount of unburned fuel trapped in the crevice regions, and calculates the portion of this trapped unburned fuel that is lost to the crankcase and the portion that returns to the combustion chamber. The effects of changes in ring gap area, volume of the crevice regions, wall temperature, load and piston speed on the amount of unburned fuel returning to the combustion chamber are examined, and are related to exhaust hydrocarbon emission trends. It is shown that these crevice gases constitute a major source of unburned HC emissions, as well as a significant loss in power and efficiency.</div>
Jaagsiekte Sheep Retrovirus Is Necessary and Sufficient To Induce a Contagious Lung Cancer in Sheep (1999)

Sheep pulmonary adenomatosis (SPA) is a contagious and experimentally transmissible lung cancer of sheep resembling human bronchiolo-alveolar carcinoma. A type D retrovirus, known as jaagsiekte sheep retrovirus (JSRV), has been associated with the etiology of SPA, but its exact role in the induction of the tumor has not been clear due to the lack of (i) a tissue culture system for the propagation of JSRV and (ii) an infectious JSRV molecular clone. To investigate the role of JSRV in the etiology of SPA, we isolated a full-length JSRV proviral clone, pJSRV21, from a tumor genomic DNA library derived from a natural case of SPA. pJSRV21 was completely sequenced and showed open reading frames in agreement with those deduced for the original South African strain of JSRV. In vivo transfection of three newborn lambs by intratracheal inoculation with pJSRV21 DNA complexed with cationic lipids showed that pJSRV21 is an infectious molecular clone. Viral DNA was detected in the peripheral blood mononuclear cells (PBMCs) of the transfected animals by a highly sensitive JSRV-U3 heminested PCR at various time points ranging from 2 weeks to 6 months posttransfection. In addition, proviral DNA was detected in the PBMCs, lungs, and mediastinal lymph nodes of two lambs sacrificed 9 months posttransfection, but no macroscopic or histological SPA lesion was induced. We prepared JSRV particles by transient transfection of 293T cells with a JSRV construct (pCMV2JS21) in which the upstream U3 was replaced with the cytomegalovirus early promoter. Four newborn lambs were inoculated with JSRV21 particles produced in this manner, and two of them showed the classical signs of SPA 4 months postinfection. The resulting tumors were positive for JSRV DNA and protein. Thus, JSRV21 is an infectious and pathogenic molecular clone and is necessary and sufficient to induce sheep pulmonary adenomatosis.
Syntheses of <sup>14</sup>C‐labelled monoacidic metabolites of dithiopyr (1991)

Abstract Convenient methods for the selective hydrolysis of the thioester groups of dithiopyr to the corresponding carboxylic acid are described. 2‐(Difluoromethyl)‐4‐(2‐methylpropyl)‐5‐[(methylthio)carbonyl]‐6‐(trifluoromethyl)‐3‐pyridine‐4‐ 14 C‐carboxylic acid ( 2 ) was obtained by simple potassium hydroxide hydrolysis of 14 C‐labelled dithiopyr. A more involve strategy was necessary for the preparation of the isomeric carboxylic acid 6‐(difluoromethyl)‐4‐(2‐methylpropyl)‐5‐[(methylthio) carbonyl]‐2‐(trifluoromethyl)‐3‐pyridine‐4‐ 14 C‐carboxylic acid ( 3 )
Antimicrobial lipids: Natural and synthetic fatty acids and monoglycerides (1977)

Over 40 natural or synthetic lipophilic compounds were screened for antimicrobial activity. Gram (+) bacteria and yeasts but not Gram (-) bacteria were affected by these agents. Epimino and selena fatty acids are more active than their corresponding straight chain unsubstituted fatty acids. The position of selenium influenced the antimicrobial activity of the fatty acids. The presence and position of a double or triple bond, usually an important factor in long chain fatty acids (greater than C14) had little or no effect in C11 fatty acids. Optimum antimicrobial activity was found for fatty acids and their corresponding monoglycerides when the chain lenght was C12. The dilaurin derivative was not active.
Synthesis of Transparent Magadiite−Silica Hybrid Monoliths (2002)

The synthesis of optically transparent magadiite−silica hybrid monoliths was investigated by the incorporation of delaminated magadiite powders into a sol−gel-derived silica matrix obtained by hydrolysis and condensation of tetramethoysilane (or tetramethyl orthosilicate or TMOS). The delamination of sodium magadiite was accomplished by the intercalation of laurylpyridinium ions (LPy+) into the particles followed by ion exchange with Na+. The resulting fine platelike crystallites was found to be useful in obtaining a magadiite−silica monolith. The present procedures were effective in the preparation of homogeneous and transparent magadiite−silica monoliths and were found to be significantly superior to the conventional method of alkylsilylation with hexamethyldisilazane (HMDS).