gebhart/patrepeval huggingface dataset:
Kinetic study of a highly active MgCl<sub>2</sub>‐supported Ziegler–Natta catalyst in liquid pool propylene polymerization. II. The influence of alkyl aluminum and alkoxysilane on catalyst activation and deactivation (2002)

Abstract The influence of alkyl aluminum and alkoxysilane on the kinetics in liquid pool propylene batch polymerization was investigated with a highly active Ziegler–Natta catalyst system that consisted of MgCl 2 /TiCl 4 /diester–alkoxysilane/AlR 3 . In this study, diethyl phthalate and t ‐BuEtSi(OMe) 2 were used as a diester and an alkoxysilane, respectively. The catalyst activity depended on the concentration of the alkyl aluminum when it came into contact with the catalyst. In addition, alkoxysilane as an external donor had a role in activating the catalyst. With respect to activity decay, the overreduction of Ti did not seem to be the cause. Instead, the decay rate decreased with an increasing alkoxysilane/catalyst ratio. This implied that activity decay was caused by the formation of dormant sites after 2,1‐misinsertion of propylene. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 83: 2669–2679, 2002
IPv4 over MAPOS Version 1 (1997)

This document describes a protocol for transmission of the Internet Protocol Version 4 (IPv4) over Multiple Access Over SONET/SDH (MAPOS) version 1. MAPOS is a link layer protocol and provides multiple access capability over SONET/SDH links. IP runs on top of MAPOS. This document explains IP datagram encapsulation in HDLC frame of MAPOS, and the Address Resolution Protocol (ARP).
Glycosylated PROLI/NO Derivatives as Nitric Oxide Prodrugs (2009)

GlcNAc-PROLI/NO prodrugs that are activated by N-acetylglucosaminidase to release nitric oxide (NO) are described. A classical acid-amine coupling is used to bifunctionalize these PROLI/NO prodrugs, which on activation generate up to 4 mol of NO, a peptide residue, and an N-acetylglucosamine residue. Many of the prodrugs synthesized are efficient sources of intracellular NO.
A Mass Spectrometric Determination of the Conformation of Dimeric Apolipoprotein A-I in Discoidal High Density Lipoproteins (2005)

Discoidal forms of high density lipoproteins (HDL) are critical intermediates between lipid-poor apolipoprotein A-I (apo A-I), the major protein constituent of HDL, and the mature spherical forms that comprise the bulk of circulating particles. Thus, many studies have focused on understanding apoA-I structure in discs reconstituted in vitro. Recent theoretical and experimental work supports a "belt" model for apoA-I in which repeating amphipathic helical domains run parallel to the plane of the lipid disc. However, disc-associated apoA-I can adopt several tertiary arrangements that are consistent with a belt orientation. To distinguish among these, we cross-linked near-neighbor Lys groups in homogeneous 96 A discs containing exactly two molecules of apoA-I. After delipidation and tryptic digestion, mass spectrometry was used to identify 9 intermolecular and 11 intramolecular cross-links. The cross-linking pattern strongly suggests a "double-belt" molecular arrangement for apoA-I in which two apoA-I molecules wrap around the lipid bilayer disc forming two stacked rings in an antiparallel orientation with helix 5 of each apoA-I in juxtaposition (LL5/5 orientation). The data also suggests the presence of an additional double-belt orientation with a shifted helical registry (LL5/2 orientation). Furthermore, a 78 A particle with two molecules of apoA-I fit a similar double-belt motif with evidence for conformational changes in the N-terminus and the region near helix 5. A comparison of this work to a previous study is suggestive that a third molecule of apoA-I can form a hairpin in larger particles containing three molecules of apoA-I.
ChemInform Abstract: Condensed Thienopyrimidines. Part 5. Studies on the Thermal Cyclization of Various ortho‐Formylthiophene Carbamates with Ethanolamine. (1989)

Abstract The (het)aromatic aldehydes (I) and (VII) react with ethanolamine (II) to give the Schiff bases (III) and (VIII).
Machine Vision: Lighting (2015)

Today's machine vision systems are more versatile and more capable than ever before, but the key to success still remains in providing a good image to process. What is most important in machine vision is how the image looks to the computer. This entry describes the considerations of part optical properties and application needs to consider in designing lighting for machine vision. This entry also describes the various types of light sources that are in use today in machine vision and discusses the use of the basic techniques of lighting most commonly used in machine vision applications.
On the reductive amination of aldehydes and ketones catalyzed by homogeneous Rh(i) complexes (2000)

The homogeneously catalyzed reductive amination of aldehydes and ketones under smooth conditions is reported, showing for the first time, that Rh(I) catalysts based on chelating diphosphines and diphosphinites can be advantageously employed for this reaction, even for the production of chiral amino acid derivatives.
Dictionary of information and library management (2006)

This comprehensive dictionary covers all aspects of librarianship and information and knowledge management. Designed to equip the trainee librarian or information management student with core industry terminology, this fully revised edition includes thousands of terms connected with information management, classification, cataloguing and electronic knowledge management. Handy supplements include proof correcting marks, classification systems, book prizes and awards, information skills, and a list of key resources on the Web. Clear and concise...a useful little handbook - Library & Information Update
Carbon-nanotube-interfaced glass fiber scaffold for regeneration of transected sciatic nerve (2014)

Carbon nanotubes (CNTs), with their unique and unprecedented properties, have become very popular for the repair of tissues, particularly for those requiring electrical stimuli. Whilst most reports have demonstrated in vitro neural cell responses of the CNTs, few studies have been performed on the in vivo efficacy of CNT-interfaced biomaterials in the repair and regeneration of neural tissues. Thus, we report here for the first time the in vivo functions of CNT-interfaced nerve conduits in the regeneration of transected rat sciatic nerve. Aminated CNTs were chemically tethered onto the surface of aligned phosphate glass microfibers (PGFs) and CNT-interfaced PGFs (CNT-PGFs) were successfully placed into three-dimensional poly(L/D-lactic acid) (PLDLA) tubes. An in vitro study confirmed that neurites of dorsal root ganglion outgrew actively along the aligned CNT-PGFs and that the CNT interfacing significantly increased the maximal neurite length. Sixteen weeks after implantation of a CNT-PGF nerve conduit into the 10 mm gap of a transected rat sciatic nerve, the number of regenerating axons crossing the scaffold, the cross-sectional area of the re-innervated muscles and the electrophysiological findings were all significantly improved by the interfacing with CNTs. This first in vivo effect of using a CNT-interfaced scaffold in the regeneration process of a transected rat sciatic nerve strongly supports the potential use of CNT-interfaced PGFs at the interface between the nerve conduit and peripheral neural tissues.
Lyme Neuroborreliosis: Evidence for Persistent Up‐Regulation of <i>Borrelia Burgdorferi</i>‐Reactive Cells Secreting Interferon‐γ (1995)

The T-cell response to the aetiologic pathogen Borrelia (B.) burgdorferi in patients with Lyme neuroborreliosis (LN) and in control patients with other neurological diseases was examined by enumerating B. burgdorferi-reactive T cells secreting interferon-gamma (IFN-gamma) with an ELIspot assay. LN patients had elevated numbers of B. burgdorferi-reactive IFN-gamma secreting cells in blood and approximately 20-fold enriched in the cerebrospinal fluid (CSF). A positive correlation existed in CSF between B. burgdorferi-reactive IFN-gamma secreting cells and B cells secreting anti-B. burgdorferi IgG antibodies. The up-regulation of antigen-specific IFN-gamma secreting cells persisted in peripheral blood up to at least 9 months and in the CSF for at least 4 months after termination of treatment with antibiotics, when the patients were mostly free from clinical signs and symptoms due to LN. How IFN-gamma interplays with other cytokines and influences the pathogenesis of LN remains to be studied.
Louis-Philippe AUDET, Histoire du Conseil de l'instruction publique de la province de Québec, 1856-1964 (1965)

Louis-Philippe AUDET, Histoire du Conseil de l'instruction publique de la province de Québec, 1856-1964. Un article de la revue Recherches sociographiques (Les classes sociales au Canada français) diffusée par la plateforme Érudit.
Decreased urinary concentration of Tamm–Horsfall protein is associated with development of renal failure and cardiovascular death within 20 years in type 1 but not in type 2 diabetic patients (2008)

A decreased u-THP was associated with an eight-fold increased risk of cardiovascular death and uraemia in type 1 but not in type 2 diabetic patients.
Hydrogen Sulfide Promotes Root Organogenesis in <i>Ipomoea batatas, Salix matsudana</i> and <i>Glycine max</i> (2009)

In this report, we demonstrate that sodium hydrosulfide (NaHS), a hydrogen sulfide (H(2)S) donor, promoted adventitious root formation mediated by auxin and nitric oxide (NO). Application of the H(2)S donor to seedling cuttings of sweet potato (Ipomoea batatas L.) promoted the number and length of adventitious roots in a dose-dependent manner. It was also verified that H(2)S or HS(-) rather than other sulfur-containing components derived from NaHS could be attributed to the stimulation of adventitious root formation. A rapid increase in endogenous H(2)S, indole acetic acid (IAA) and NO were sequentially observed in shoot tips of sweet potato seedlings treated with HaHS. Further investigation showed that H(2)S-mediated root formation was alleviated by N-1-naphthylphthalamic acid (NPA), an IAA transport inhibitor, and 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (cPTIO), an NO scavenger. Similar phenomena in H(2)S donor-dependent root organogenesis were observed in both excised willow (Salix matsudana var. tortuosa Vilm) shoots and soybean (Glycine max L.) seedlings. These results indicated that the process of H(2)S-induced adventitious root formation was likely mediated by IAA and NO, and that H(2)S acts upstream of IAA and NO signal transduction pathways.
An important milestone of distributed fiber optical sensing technology: Separate temperature and strain in single SM fiber (2009)

In the paper, the principle and performance tests of hybrid Brillouin-Rayleigh system are presented. The system allows one to independently measure strain and temperature using single SM optical fiber over long distances.
Reliability study and failure analysis of fine pitch solder-bumped flip chip on low-cost flexible substrate without using stiffener (2003)

In flip chip on flex (FCOF) technology, the flexible substrate and the assembly process are essential for the reliability of solder joints. In this research, fine-pitch solder-bumped chips with various chip sizes were assembled on flexible substrates using FCOF technology. The five types of layout design were evaluated for their effects on the assembly process and reliability of FCOF technology. It was found that appropriate substrate layout designs provided more accurate control of the wetting area because they minimized the misalignment between the copper pad and the solder mask opening. The concept of wetting area error ratio is introduced to evaluate the variation of the wetting area on the various layout designs. The shapes of solder joints formed are also related to the flex designs. Die shear test was performed for the samples of FCOF without underfill materials to study the adhesion strength of the copper pad, the solder mask and the base layer. The failed samples after thermal cycling and HAST were analyzed using SAM, an X-ray imaging system, cross-sectioning, and scanning electron microscopy (SEM).
Abstract 641: PEGylated recombinant hyaluronidase PH20 (PEGPH20) enhances tumor infiltrating CD8+ T cell accumulation and improves checkpoint inhibitor efficacy in murine syngeneic breast cancer models (2017)

Abstract Hyaluronan (HA) is an extracellular glycosaminoglycan that accumulates in the tumor microenvironment (TME) of many solid tumors and is associated with rapid tumor progression and poor prognosis. In preclinical studies, enzymatic degradation of TME HA by intravenous PEGylated recombinant human hyaluronidase PH20 (PEGPH20) remodels the TME, reduces tumor interstitial fluid pressure, decompresses tumor blood vessels, and facilitates delivery of chemotherapeutics. We have previously shown that PEGPH20-mediated HA degradation enhances anti-PD-L1 and anti-PD1 efficacy in an HA accumulating murine pancreatic tumor model (Rosengren, AACR 2016 poster #4886). Accordingly, we aimed to extend these checkpoint blockade studies into orthotopic breast cancer models; while further elucidating the effect of PEGPH20-mediated HA degradation on modulating tumor infiltrating lymphocytes (TILs). The mammary fat pads of BALB/c mice were inoculated with either EMT-6 cells or 4T1/HAS3, a 4T1 cell line engineered to over-express hyaluronan synthase-3. During tumor progression, both EMT-6 and 4T1/HAS3 mammary carcinomas accumulate high levels of HA (average 730 ng/mg and 1408 ng/mg, respectively). When treated with PEGPH20 alone (0.0375mg/kg), EMT-6 tumor growth was inhibited by ≥30% (p=0.01). Additional EMT-6 studies were conducted to evaluate PEGPH20 in combination with anti-PD-L1. PEGPH20 increased anti-PD-L1 efficacy by 38% relative to anti-PD-L1 alone (86% vs 62.4% tumor growth inhibition (TGI), p=0.0024). Comparable tumor growth experiments were conducted in the 4T1/HAS3 model. TILs were evaluated by flow cytometry. PEGPH20-mediated HA removal enhanced both checkpoint efficacy and CD8+ T cell recruitment. Specifically, PEGPH20 alone (1mg/kg) increased anti-PD-L1 efficacy by 411% relative to anti-PD-L1 alone (93% vs 18.2% TGI, p&lt;0.0001) and increased the accumulation of CD8+ TIL by 176% (p=0.0025). Taken together, the data suggest that tumor HA accumulation may act as a barrier to immune cell access and negatively modulate CD8+ TILs, and that PEGPH20-mediated HA reduction facilitates increased access of CD8+ T cells. This increased recruitment may contribute to the enhanced anti-PD-L1 efficacy observed when combined with PEGPH20. A Phase 1 trial is ongoing to evaluate PEGPH20 plus checkpoint blockade in patients with advanced or metastatic non-small cell lung cancer and in patients with locally advanced or metastatic gastric adenocarcinoma (NCT02563548). Citation Format: Renee Clift, Jisook Lee, Curtis B. Thompson, Yujun Huang. PEGylated recombinant hyaluronidase PH20 (PEGPH20) enhances tumor infiltrating CD8+ T cell accumulation and improves checkpoint inhibitor efficacy in murine syngeneic breast cancer models [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 641. doi:10.1158/1538-7445.AM2017-641
Gross primary production estimation from MODIS data with vegetation index and photosynthetically active radiation in maize (2010)

Gross primary production (GPP) is a significant important parameter for carbon cycle and climate change research. Remote sensing combined with other climate and meteorological data offers a convenient tool for large‐scale GPP estimation. GPP was estimated as a product of vegetation indices (VIs) and photosynthetically active radiation (PAR). Four kinds of vegetation indices [the normalized difference vegetation index (NDVI), the weighted difference vegetation index, the soil‐adjusted vegetation index, and the enhanced vegetation index (EVI)] derived from the Moderate Resolution Imaging Spectroradiometer daily surface reflectance product were selected to test our method. The in situ GPP was calculated using the eddy covariance technique and the PAR data were acquired from meteorological measurements. Because VIs were found to be a reliable proxy of both light use efficiency (LUE) and the fraction of absorbed PAR ( f APAR ; R 2 of 0.63–0.87 for LUE and 0.69–0.76 for f APAR ), the product VI × VI × PAR is used as a measure of GPP according to Monteith logic. Moderate determination coefficients R 2 from 0.65 for NDVI to 0.71 for EVI were obtained when GPP was estimated from a single index in maize. When testing our method, calculating GPP as a product of VI × VI × PAR, the determination coefficients R 2 largely improved, fluctuating from 0.81 to 0.91. EVI × EVI × PAR provided the best estimation of GPP with the highest R 2 of 0.91 because EVI was found to be the best indicator of both LUE and f APAR ( R 2 of 0.87 and 0.76, respectively). These results will be helpful for the development of future GPP estimation models.
Delegation of Powers (1939)

A LTHOUGH it is customary for the functions of a library authority in England to be exercised by a committee, it is not compulsory for a library authority to delegate its powers and duties, except in the case of a county council and a county borough council adopting the Acts after 1919. In these cases all matters relating to the exercise of powers under the Acts, except as to rating and borrowing, must stand referred to the education committee. That committee may delegate all or any of their library powers to a sub‐committee. In Scotland, however, the library committee has certain duties conferred upon it by statute and it does not function merely at the pleasure of the council. The power to appoint a committee and delegate powers to such a committee contained in section 15(3) of the Public Libraries Act, 1892 , was repealed and replaced, except as to London, by the Local Government Act, 1933 , which provides that a local authority may appoint a committee for any general or special purpose which it is thought would be better regulated and managed by means of a committee and it may delegate to such a committee, with or without restrictions as may be thought fit, any functions exercisable by the local authority either with respect to the whole or part of the area of the authority. Certain powers are, however, reserved exclusively to the local authority, namely, the power to levy or to issue a precept for a rate and to borrow money. The powers of the 1892 Act so far as London is concerned are virtually superseded by the London County Council (General Powers) Act, 1934 , which enables local authorities to appoint committees in terms similar to those contained in the Local Government Act .
Leakage of Cellular Contents and Morphological Changes in Resting <i>Escherichia coli</i> B Cells Exposed to an Alternating Current (1985)

Journal Article Leakage of Cellular Contents and Morphological Changes in Resting Escherichia coli B Cells Exposed to an Alternating Current Get access Keiko Shimada, Keiko Shimada Department of Industrial Chemistry, Faculty of Engineering, Seikei University, Musashino-shi, Tokyo 180, Japan Search for other works by this author on: Oxford Academic Google Scholar Kenzo Shimahara Kenzo Shimahara Department of Industrial Chemistry, Faculty of Engineering, Seikei University, Musashino-shi, Tokyo 180, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 49, Issue 12, 1 December 1985, Pages 3605–3607, https://doi.org/10.1080/00021369.1985.10867315 Published: 01 December 1985 Article history Received: 13 June 1985 Published: 01 December 1985
Design of a self-correcting active pixel sensor (2002)

Digital cameras are growing ever larger in silicon area and pixel count, which increases the occurrence of defects at fabrication time, or dead pixels that develop over their lifetime. An active pixel sensor self-correcting for most common faults is created by splitting the photodiode and readout transistors into two parallel portions with only a small area cost. Simulations show operation is the same for a single large device with no faults. When one half of the redundant pixel is stuck at low, output over a wide current range is reduced by 1.98 to 2.01. For one half stuck at high, faults output, after offset removal, is reduced by a factor of 1.85 to 1.92. Hence self-correction of the pixel can be performed with good accuracy via a simple shift circuit and with high accuracy with digital processing. Variation in transistor threshold voltages between the pixel halves of even 10% only causes modification of factors by 2-4%, hence giving a small effect.
Plasminogen Activator and Plasminogen Activator Inhibitor I Release during Experimental Endotoxaemia in Chimpanzees: Effect of Interventions in the Cytokine and Coagulation Cascades (1995)

1. Disseminated intravascular coagulation frequently accompanies Gram-negative sepsis and may contribute to widespread deposition of microthrombi. Besides the endotoxin-induced activation of coagulation, an important role for the fibrinolytic system has been postulated. The precise mechanisms underlying these fibrinolytic changes during endotoxaemia are not known but have been suggested to be mediated directly by cytokines or secondary to thrombin generation. 2. In the present study we have delineated in detail the fibrinolytic response to a bolus injection of endotoxin in non-human primates and analysed the contribution of cytokines and thrombin generation to the endotoxin-induced release of tissue-type plasminogen activator and plasminogen activator inhibitor 1. Chimpanzees received a bolus injection of endotoxin alone or in combination with blocking monoclonal antibodies directed against tumour necrosis factor or interleukin 6 or in combination with pentoxifylline. Furthermore, to assess the effect of coagulation activation on the activation of fibrinolysis, another group of chimpanzees received endotoxin in combination with either anti-tissue factor antibodies or recombinant hirudin. 3. Infusion of endotoxin induced a rapid increase in plasminogen activator activity and tissue-type plasminogen activator antigen levels and subsequent plasmin generation, reaching peak levels 2h after endotoxin administration. Plasminogen activator inhibitor 1 levels remained constant for the first 2 h, after which time a steep increase was observed. Plasminogen activator activity and plasmin generation decreased simultaneously with the rise in plasminogen activator inhibitor 1 levels. Fibrinolytic activity remained suppressed during the remainder of the study owing to sustained increased levels of plasminogen activator inhibitor 1. The administration of pentoxifylline strongly attenuated the release of tissue-type plasminogen activator and plasminogen activator inhibitor 1, whereas the antitumour necrosis factor antibodies blocked the fibrinolytic response entirely. In contrast, interleukin 6-neutralizing antibodies did not affect the fibrinolytic response. Although endotoxin-induced generation of thrombin was completely prevented by the administration of tissue factor-neutralizing antibodies or by hirudin, no effect on the fibrinolytic response was observed.(ABSTRACT TRUNCATED AT 250 WORDS)
Spectrally encoded photonic crystal nanocavities by independent lithographic mode tuning (2011)

We demonstrate the independent lithographic mode tuning by changing the holes around the defect area of photonic crystal nanocavities containing light-emitting quantum dots. The data have been verified by the three-dimensional finite-difference time domain simulation. These findings can be applied to realize encoded particles with large coding capability (>105) for biosensing.