gebhart/patrepeval huggingface dataset:
Optical properties of quantum dots in photonic dots (2002)

A concept of <i>quantum dots in photonic dots</i> has been realized by incorporating highly luminescent CdSe nanocrystals (quantum dots) into various spherical microcavities, or 3-D photonic dots (micron-size glass, polymeric microspheres). Coupling of discrete electron states of quantum dots and photon states inside photonic dots strongly affects onto both stationary and dynamic photoluminescence properties of nanocrystals. A number of interesting optical effects is demonstrated on such structures: increase in radiative recombination rate in the vicinity of ultranarrow photon modes (Purcell effect); room temperature nearly thresholdless lasing; blinking of photon modes; single photon mode switching by single quantum dot emission.
Acoustic scattering by a partially buried three-dimensional elastic obstacle (1998)

A transition-matrix solution for the spectral scattering response of an elastic obstacle that penetrates a plane-stratified fluid host is formulated. The field scattered from the segment in each layer is expanded in a global outgoing basis centered on that segment and these segment fields are superposed at the field point. A manageable structure for the transition matrix is maintained by using the boundary conditions to couple these segment fields to the interior field of the obstacle via exterior surface field expansions centered on the primary origin of the obstacle. Two formulations are presented and compared in which the surface fields are expanded in either the standard set of regular spherical eigenfunctions of the Helmholtz equation or the spherical harmonics. Numerical tests for an axisymmetric spheroid indicate both formulations are viable but exhibit different convergence and stability characteristics. However, in both cases, convergence is better for flattened shapes (oblate) than elongated shapes (prolate). Examples are presented to illustrate environmental effects on the backscatter by a bubble and elastic spheres and spheroids that penetrate a water/sediment interface.
Measurement of Venous Flow by Continuous Thermodilution and its Application to Measurement of Mammary Blood Flow in the Goat (1966)

The thermodilution method of Fegler, previously used as a single injection technique to measure the flow in one of the main veins draining the mammary gland of goats, has been adapted to a continuous injection technique. Saline at room temperature is injected at rates of 10 to 50 ml/min for 20 to 60 sec and the blood flow is calculated directly from the fall in blood temperature downstream. The method has been checked in vivo by cannulation of the vessel and shown to be as accurate as the single injection technique and the measurement of mammary flow on the Fick principle. It is particularly valuable for determining rapidly the proportion of the mammary venous flow leaving by each of the two main veins.
Semantic sketch-based 3D model retrieval (2013)

Query-by-Sketch is an intuitive way to retrieve relevant 3D models given a user sketch. It has many promising application potentials in human computer interaction, 3D animation, game design, etc. However, it is a very challenging task due to the big semantic gap between human-drawn sketches and 3D models. A human-drawn sketch is usually composed of several simplified and exaggerated curves as the iconic representation of an object, while a 3D model of the object is generally an accurate representation of its geometry information. Such big semantic gap makes the search based on a direct 2D-3D comparison suffer low accuracy and high computational cost. In this paper, we propose a novel semantic sketch-based 3D model search to bridge the semantic gap by first recognizing the potential semantic meanings of the user sketch and then performing 2D-3D matching for the 3D models within the predicted categories. The experimental results demonstrate that our approach achieves significant improvements in both search accuracy and efficiency, which further validate that our approach can effectively bridge the semantic gap between user sketches and 3D models.
Nitric Oxide and the Heart: Update on New Paradigms (2005)

The role of nitric oxide (NO) as a regulator of cardiac contraction was suggested in the early nineties, but a consensual view of its main functions in cardiac physiology has only recently emerged with the help of experiments using genetic deletion or overexpression of the three nitric oxide synthase (NOS) isoforms in cardiomyocytes. Contrary to the effects of exogenous, pharmacologic NO donors, signaling by endogenous NO is restricted to intracellular effectors co-localized with NOS in specific subcellular compartments. This both ensures coordinate signaling by the three NOS isoforms on different aspects of the cardiomyocyte function and helps to reconcile previous apparently contradictory observations based on the use of non-isoform-specific NOS inhibitors. This review will emphasize the role of NOS on excitation-contraction coupling in the normal and diseased heart. Endothelial NOS and neuronal NOS contribute to maintain an adequate balance between adrenergic and vagal input to the myocardium and participate in the early and late phases of the Frank-Starling adaptation of the heart. At the early phases of cardiac diseases, inducible NOS reinforces these effects, which may become maladaptive as disease progresses.
A mechanism of perlite expansion (2006)

We describe a novel process for expanding perlite rocks, at temperatures from 1220 to 1370 K and elevated pressures, (3.3–16.0) × 105 Pa, in flowing water vapor. Our results demonstrate for the first time that heating markedly increases the compressive strength of perlite, reducing its viscosity and giving rise to perlite expansion in the central part of the sample owing to disruption of the rigid bonding between structural units and the formation of unstable hydrogen bridges. As a result, the mineral becomes capable of retaining the water present in the rock without cracking or shattering.
A 2.5-Gb/sec 15-mW BiCMOS clock recovery circuit (2002)

High-speed low-power clock recovery circuits find wide application in high-performance communication systems. This paper describes the design of a 2.5-Gb/sec 15-mW clock recovery circuit (CRC) fabricated in a 20-GHz 1-/spl mu/m BiCMOS technology. Employing a modified version of the "quadricorrelator" architecture, the circuit extracts the clock from a non-return-to-zero (NRZ) data sequence using both phase and frequency detection.
ChemInform Abstract: Ring‐Opening of Hindered Cyclic Epoxides with Potassium Carboxylates in the Presence of Conjugate Acids. (2014)

Abstract Optimal reaction conditions are found for the ring‐opening of hindered epoxides with potassium carboxylates.
Membrane Association of VP22, a Herpes Simplex Virus Type 1 Tegument Protein (2003)

Tegument proteins of herpes simplex virus type 1 (HSV-1) are hypothesized to contain the functional information required for the budding or envelopment process proposed to occur at cytoplasmic compartments of the host cell. One of the most abundant tegument proteins of HSV-1 is the U(L)49 gene product, VP22, a 38-kDa protein of unknown function. To study its subcellular localization, a VP22-green fluorescent protein chimera was expressed in transfected human melanoma (A7) cells. In the absence of other HSV-1 proteins, VP22 localizes to acidic compartments of the cell that may include the trans-Golgi network (TGN), suggesting that this protein is membrane associated. Membrane pelleting and membrane flotation assays confirmed that VP22 partitions with the cellular membrane fraction. Through truncation mutagenesis, we determined that the membrane association of VP22 is a property attributed to amino acids 120 to 225 of this 301-amino-acid protein. The above results demonstrate that VP22 contains specific information required for targeting to membranes of acidic compartments of the cell which may be derived from the TGN, suggesting a potential role for VP22 during tegumentation and/or final envelopment.
Induction of Human Airway Smooth Muscle Apoptosis by Neutrophils and Neutrophil Elastase (2005)

Neutrophils are an important component of airway inflammation and may interact with human airway smooth muscle cells (HASMC). We investigated the effect of neutrophils and of neutrophil-derived proteases on HASMC survival. When co-incubated with neutrophils (0.1-1 x 10(6) cells/ml), attachment of human ASMC was reduced to 12.3 +/- 4.3% compared with untreated controls after 72 h. HASMC showed nuclear condensation and fragmentation (41.6 +/- 8.1% compared with baseline of 3.1 +/- 0.4%), and the biochemical markers of apoptosis, annexin V binding (9.7 +/- 0.7%; baseline 1.1 +/- 0.3%) and cleaved caspase-3 expression, were observed. The proteolytic activity released by neutrophils was essential for the proapoptotic effect because inhibition of elastase activity by alpha(1)-antitrypsin and MeOSuc-Ala-Ala-Pro-Ala-CMK (MSACK) reduced HASMC apoptosis. Human neutrophil elastase (0.1-3 microg/ml) induced apoptosis of HASMC, as well as other neutrophil serine proteases, cathepsin G, and proteinase 3. Fibronectin degradation products were present in HASMC supernatants exposed to neutrophil-conditioned media and to neutrophil elastase. The local release of proteases from neutrophils present in airway smooth muscle cells may lead to HASMC apoptosis as a result of matrix degradation and loss of cell attachment. This may limit pathologic changes such as ASMC hyperplasia and extracellular matrix deposition seen in airway remodeling.
Active power filter control algorithms using wavelet-based power definitions (2004)

A novel method to determine the reference filter current for an active power conditioner filtering harmonic current components and/or current contributing to reactive power is presented. It is based on definitions of active and reactive power quantities in the time-frequency domain associated to complex wavelets, allowing a better time localization than Fourier-based quantities. Its behavior is illustrated in a well-chosen single-phase example. The properties of the method are discussed and compared to traditional compensation methods.
Clinical Significance of<i>Escherichia albertii</i> (2012)

Discriminating Escherichia albertii from other Enterobacteriaceae is diffi cult. Systematic analyses showed that E. albertii represents a substantial portion of strains currently identifi ed as eae-positive Escherichia coli and includes Shiga toxin 2f-producing strains. Because E. albertii possesses the eae gene, many strains might have been misidentifi ed as enterohemorrhagic or enteropathogenic E. coli.
Energy Harvesting from the Stray Electromagnetic Field around the Electrical Power Cable for Smart Grid Applications (2016)

For wireless sensor node (WSN) applications, this paper presents the harvesting of energy from the stray electromagnetic field around an electrical power line. Inductive and capacitive types of electrodynamic energy harvesters are developed and reported. For the produced energy harvesters, solid core and split-core designs are adopted. The inductive energy harvester comprises a copper wound coil which is produced on a mild steel core. However, the capacitive prototypes comprise parallel, annular discs separated by Teflon spacers. Moreover, for the inductive energy harvesters' wound coil and core, the parametric analysis is also performed. A Teflon housing is incorporated to protect the energy harvester prototypes from the harsh environmental conditions. Among the inductive energy harvesters, prototype-5 has performed better than the other harvesters and produces a maximum rms voltage of 908 mV at the current level of 155 A in the power line. However, at the same current flow, the capacitive energy harvesters produce a maximum rms voltage of 180 mV. The alternating output of the prototype-5 is rectified, and a super capacitor (1 F, 5.5 V) and rechargeable battery (Nickel-Cadmium, 3.8 V) are charged with it. Moreover, with the utilization of a prototype-5, a self-powered wireless temperature sensing and monitoring system for an electrical transformer is also developed and successfully implemented.
A Practical, Nenitzescu-Based Synthesis of LY311727, the First Potent and Selective s-PLA<sub>2</sub> Inhibitor (1996)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTA Practical, Nenitzescu-Based Synthesis of LY311727, the First Potent and Selective s-PLA2 InhibitorJ. M. Pawlak, V. V. Khau, D. R. Hutchison, and M. J. MartinelliView Author Information Chemical Process Research & Development, Lilly Research Laboratories, A Division of Eli Lilly and Company, Indianapolis, Indiana 46285-4813 Cite this: J. Org. Chem. 1996, 61, 25, 9055–9059Publication Date (Web):December 13, 1996Publication History Received30 July 1996Published online13 December 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jo9614452https://doi.org/10.1021/jo9614452brief-reportACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views1520Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alcohols,Chemical reactions,Nitrogen compounds,Organic compounds,Solvents Get e-Alerts
Plasma carnitine in women. Effects of the menstrual cycle and of oral contraceptives. (1983)

The plasma concentrations of carnitine were determined in a group of 35 women and 35 men admitted to a clinic, and in another group of 18 women during their menstrual cycle. The values found for the women (45.1 +/- 2.6 nmol/ml of free carnitine and 59.1 +/- 2.8 nmol/ml of total carnitine) were not significantly different from the values obtained in men (respectively 42.4 +/- 1.7 and 55.5 +/- 1.9 nmol/ml). No direct relationship between the free or total carnitine concentrations and the concentrations of circulating lipids could be demonstrated. During the menstrual cycle the plasma concentrations of free and total carnitine remained unchanged. Intake of oral contraceptives caused an elevation in blood triacylglycerols and decreases in the levels of luteinizing hormone, follicle-stimulating hormone, and free and total carnitine.
Energy Converting NADH: Quinone Oxidoreductase (Complex I) (2006)

NADH:quinone oxidoreductase (complex I) pumps protons across the inner membrane of mitochondria or the plasma membrane of many bacteria. Human complex I is involved in numerous pathological conditions and degenerative processes. With 14 central and up to 32 accessory subunits, complex I is among the largest membrane-bound protein assemblies. The peripheral arm of the L-shaped molecule contains flavine mononucleotide and eight or nine iron-sulfur clusters as redox prosthetic groups. Seven of the iron-sulfur clusters form a linear electron transfer chain between flavine and quinone. In most organisms, the seven most hydrophobic subunits forming the core of the membrane arm are encoded by the mitochondrial genome. Most central subunits have evolved from subunits of different hydrogenases and bacterial Na+/H+ antiporters. This evolutionary origin is reflected in three functional modules of complex I. The coupling mechanism of complex I most likely involves semiquinone intermediates that drive proton pumping through redox-linked conformational changes.
Gate leakage current reduction with advancement of graded barrier AlGaN/GaN HEMT (2011)

The gate leakage current reduction solution of AlGaN/GaN HEMT device issue has been addressed in this paper with compositional grading of AlGaN barrier layer. This work is also conjugated with the critical thickness limitation of heterostructure material growth. Hence, critical thickness calculation of AlGaN over GaN has been kept in special view. 1D Schrodinger and Poisson solver was used to calculate the 2DEG concentration and effective location to use it in the ATLAS device simulator for the predictions. The proposed Al0.50Ga0.50N/Al0.35Ga0.65N/Al0.20Ga0.80N/GaN HEMT structure exhibits the leakage current of the order of around 15 nA/mm at gate voltage of 1 V.
Characterization of (24R)-24,25-dihydroxyvitamin D3monoglucuronides formed from a rat liver microsomal fraction using high-performance liquid chromatography and liquid chromatography–mass spectrometry (1998)

The characterization of (24R)-24,25-dihydroxyvitamin D3 monoglucuronides obtained from an invitro study was performed using high-performance liquid chromatography and liquid chromatography–mass spectrometry. In the presence of rat liver microsomal fraction and uridine-5′-diphosphoglucuronic acid, (24R)-24,25-dihydroxyvitamin D3 gave 3- and 24-glucuronides as the main products in almost equal amounts, but only a small amount of the corresponding 25-glucuronide was obtained. The glucuronides were identified by comparison with three positional isomers of standard synthetic samples, syntheses of which are briefly described, based on their chromatographic behavior and mass spectral data.
Reverse chromosome painting: a method for the rapid analysis of aberrant chromosomes in clinical cytogenetics. (1992)

We describe a method, termed reverse chromosome painting, which allows the rapid analysis of the content and breakpoints of aberrant chromosomes. The method involves the sorting of small numbers of the aberrant chromosome from short term blood culture preparations or cell lines by using bivariate flow karyotype analysis. The sorted chromosomes are amplified and biotin labelled enzymatically using a degenerate oligonucleotide-primed polymerase chain reaction (DOP-PCR), the product annealed to metaphase spreads from normal subjects, and hybridisation detected using fluorescence in situ hybridisation (FISH). We show the usefulness of this method for routine clinical cytogenetics by the analysis of cases involving an insertion, a deletion, a translocation, and two cases of a chromosome with additional material of unknown origin. The method has particular application for the rapid resolution of the origin of de novo unbalanced chromosome duplications.
The Klynac: An integrated klystron and linear accelerator (2013)

The Klynac concept integrates an electron gun, a radio frequency (RF) power source, and a coupled-cavity linear accelerator into a single resonant system. The klystron is essentially a conventional klystron structure with an input cavity, some number of intermediate cavities and an output cavity. The accelerator structure is, likewise, a conventional on-axis coupled structure. The uniqueness is the means of coupling the klystron output cavity to the accelerator. The coupler is a resonant coupler rather than an ordinary transmission line. The geometry of such a system need not be coaxial. However, if the klystron and accelerator are coaxial we can eliminate the need for a separate cathode for the accelerator by injecting some of the klystron beam into the accelerator. Such a device can be made cylindrical which is ideal for some applications.
Inactivation of Factor XIa by Plasma Protease Inhibitors (1982)

Factor XIa is a plasma protease that, by activating Factor IX, plays an important role in the early phase of the intrinsic pathway of blood coagulation. Four plasma protease inhibitors, alpha(1)-protease inhibitor, antithrombin III, C1-inhibitor, and alpha(2)-plasmin inhibitor, have been reported to inactivate human Factor XIa, but their quantitative contribution to the inactivation of Factor XIa in plasma has not been fully assessed. Using purified systems, we observed that the second-order rate constants for the reaction of Factor XIa with alpha(1)-protease inhibitor, antithrombin III, and CI-inhibitor were 4.08, 10, and 14.6 M(-1) min(-1) x 10(3), respectively. The pseudo-first-order rate constants, at plasma concentration of the inhibitors, were 1.86 x 10(-1), 4.68 x 10(-2), and 2.4 x 10(-2) min(-1), respectively. These kinetic data predict that alpha(1)-protease inhibitor should account for 68%, antithrombin III for 16%, and C1-inhibitor and the equipotent alpha(2)-plasmin inhibitor each for 8% of the total inhibitory activity of plasma against Factor XIa. The rate of inactivation of Factor XIa in various plasma samples specifically deficient in inhibitors was consistent with these predictions. Factor XI, the zymogen form of Factor XIa, circulates in plasma associated with the contact system cofactor, high molecular weight kininogen (HMW kininogen). Kinetic analysis indicated the existence of a reversible bimolecular Factor XIa-HMW kininogen complex with a dissociation constant (K(d)) = 0.17 muM. The light chain derived from HMW kininogen decreased the inactivation rate of Factor XIa by C1-inhibitor with a K(d) of 0.08 muM for a complex of Factor XIa and the light chain derived from HMW kininogen. The protective effect of HMW kininogen was confirmed by the finding that the inactivation rate of Factor XIa in kininogen-deficient plasma was increased over normal plasma. The present study confirms that alpha(1)-protease inhibitor is the major inhibitor of Factor XIa in plasma, and that the formation of a reversible complex between Factor XIa and HMW kininogen decreases the rate of inactivation of the enzyme by its inhibitors.
Bacillus peoriae sp. nov. (1993)

The taxonomy of an apparently genetically distinct gas-producing group of Bacillus strains formerly classified as Bacillus polymyxa was studied. Multilocus enzyme electrophoresis analysis confirmed the distinctiveness of the unknown taxon. Low DNA relatedness values also demonstrated that the unknown was not closely related genetically to any of the presently recognized species that have guanine-plus-cytosine values of 45 to 47 mol% or produce gas by fermentation of sugars. The unknown group was also a phenotypically distinct taxon. The data suggest that the unknown group merits recognition as a new species, for which the name Bacillus peoriae is proposed.
Administration of Human Somatotropin in Levodopa-Treated Patients With Parkinsonism (1979)

To investigate further the role of growth hormone (GH) on the cerebral effects of levodopa, human somatotropin (human growth hormone) was administered to four patients with parkinsonism with varying response to chronic levodopa therapy. The doses of somatotropin (5 IU) were administered on alternate days for four days, and the effects of this hormone on the patient's symptomatic control, dyskinesia, plasma GH, and dopa levels were evaluated and compared with those of patients receiving saline injections. We have demonstrated that administration of exogenous human somatotropin, even during marked and sustained elevations of plasma GH levels, does not alter the therapeutic or side effects of levodopa therapy. With one exception, plasma dopa levels after human somatotropin administration remained unchanged. We conclude that neither the endogenous increases of GH in response to levodopa nor those attained following human somatotropin administration modify in any consistent way the therapeutic and side effects of chronic levodopa therapy, and that the episodic releases of GH in response to levodopa occur independently of its cerebral effects.