gebhart/patrepeval huggingface dataset:
Feedback loop between cerebellum and septal-hippocampal sites: its role in emotion and epilepsy. (1980)

Data collected in animal studies suggest the existence of a feedback loop between the cerebellum, septal region, and hippocampus, the same sites where anatomic connections were demonstrated in previous studies. In monkeys, stimulation through the vermis of the cerebellum inhibits epileptiform electroencephalographic activity at these supratentorial subcortical sites. In cats, macrostimulation of one of these sites consistently affects each of the other sites, either by facilitation or inhibition of unit activity. Further, in cats, there is a consistent relation between unit activity of the Purkinje cells and seizural activity in the septal region and hippocampus induced by hippocampal stimulation. Facilitation of Purkinje cell activity by the seizural activity appears to play a role in stopping the seizure. The possibility that the feedback relation is involved in epilepsy and emotional disorders and the mechanism by which cerebellar vermal stimulation has been useful in the treatment of these disorders are considered.
Human Parainfluenza Virus 4 Outbreak and the Role of Diagnostic Tests (2005)

Owing to the difficulties in isolating the virus and the lack of routine surveillance, the clinical significance of human parainfluenza virus 4 (HPIV-4) is less well defined than that of the other human parainfluenza viruses. We describe the first outbreak of HPIV-4 infection in a developmental disabilities unit, involving 38 institutionalized children and three staff members, during a 3-week period in autumn 2004. Most subjects had upper respiratory tract infections (URTI), while lower respiratory tract infections (LRTI) occurred in three children (7%), one complicated by respiratory failure requiring ventilation support. All patients recovered. Nasopharyngeal aspirates tested for HPIV-4 were positive by reverse transcriptase PCR (RT-PCR) in all 41 cases (100%), by direct immunofluorescence in 29 of 39 tested cases (74%), and by cell cultures in 6 of 37 cases (16%), and serum was positive for antibodies against HPIV-4 in all 35 cases (100%) with serum samples available. In addition, RT-PCR detected HPIV-4 in four children (three LRTI and one URTI) out of 115 patients with community-acquired respiratory tract infection. Molecular analysis of the 1,198-bp phosphoprotein sequences showed that HPIV-4 isolates among the cases were genetically similar, whereas the community controls were more genetically distant, supporting nosocomial transmission of a single HPIV-4 genotype during the outbreak. Moreover, the HPIV-4 causing the outbreak is more closely related to HPIV-4A than HPIV-4B. HPIV-4 may be an important cause of more severe respiratory illness in children. The present RT-PCR assay is a sensitive, specific, and rapid method for the diagnosing HPIV-4 infection. To better define the epidemiology and clinical spectrum of disease of HPIV-4 infections, HPIV-4 should be included in the routine panels of respiratory virus detection on respiratory specimens.
Photoselective Vaporization of the Prostate: Initial Experience with a New 80 W KTP Laser for the Treatment of Benign Prostatic Hyperplasia (2003)

This pilot study indicates that PVP with the new 80 W KTP/532 laser is a simple, safe, and efficacious outpatient procedure for the treatment of obstructive BPH.
Carnitine-acylcarnitine translocase catalyzes an equilibrating unidirectional transport as well. (1980)

Besides carnitine-acylcarnitine translocase-catalyzed exchange diffusions, a relatively much slower unidirectional transport of carnitines also proceeds in mitochondria. The latter proceeds in the direction of the concentration gradient of carnitines and leads to the equilibration of carnitine concentration across the inner membrane. The same translocase that catalyzes exchange diffusion appears to catalyze unidirectional transport inasmuch as the two processes showed similar substrate specificity, sensitivity to inhibitors, high temperature coefficients, apparent affinity for carnitine, and a lack of energy requirement. The unidirectionally imported carnitine readily exchanged against medium carnitine, indicating that the two transport processes share the same pool of mitochondrial carnitine. Unidirectional transport appears to be functional in vivo; its operation seems not only to allow mitochondria to acquire carnitine but to adjust the rates of their faster exchange-diffusion reactions with changes in total tissue carnitine concentrations. The carnitine-acylcarnitine translocase was found to be about 15 times as active in mitochondria of rat liver as in those of heart.
A data model for intelligent automation systems (2002)

A programming environment for the specification, design, coding, and testing of software for intelligent automation systems is described. The programming environment supports the following: development of programs, maintain the consistency of object, and support distributed systems. The information to be managed include to be traced items (e.g., engines, automobile roofs, etc.), programs (e.g., for robots), data (monitoring) machines, etc. The author takes a holistic approach incorporating objects for control, management, and communication. The object implementation is done using the C++ language in an IBM/AT environment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
On reducing computational complexity of codebook search in CELP coder through the use of algebraic codes (2002)

A general framework is introduced which allows both fast search and freedom in designing codebooks with good statistical properties. Several previously proposed schemes are compared from this viewpoint. A backward filtering formulation is given to show that sparse algebraic codes (SACs) (i.e., with few nonzero components) offer distinct advantages. It is shown that they reduce the optimal-search computation per codeword. They also allow control of the statistical properties of the codebook in the time and frequency domains. This control can be dynamic in the sense that it can be made to evolve as a function of the linear predictive coding model A(z). The algebraic-code excited linear prediction (ACELP) technology which allows full duplex operation on a single TMS320C25 at rates between 4.8 and 16 kb/s and which is based on SAC-driven dynamic codebooks is described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A High-Voltage SOI CMOS Exciter Chip for a Programmable Fluidic Processor System (2007)

A high-voltage (HV) integrated circuit has been demonstrated to transport fluidic droplet samples on programmable paths across the array of driving electrodes on its hydrophobically coated surface. This exciter chip is the engine for dielectrophoresis (DEP)-based micro-fluidic lab-on-a-chip systems, creating field excitations that inject and move fluidic droplets onto and about the manipulation surface. The architecture of this chip is expandable to arrays of N X N identical HV electrode driver circuits and electrodes. The exciter chip is programmable in several senses. The routes of multiple droplets may be set arbitrarily within the bounds of the electrode array. The electrode excitation waveform voltage amplitude, phase, and frequency may be adjusted based on the system configuration and the signal required to manipulate a particular fluid droplet composition. The voltage amplitude of the electrode excitation waveform can be set from the minimum logic level up to the maximum limit of the breakdown voltage of the fabrication technology. The frequency of the electrode excitation waveform can also be set independently of its voltage, up to a maximum depending upon the type of droplets that must be driven. The exciter chip can be coated and its oxide surface used as the droplet manipulation surface or it can be used with a top-mounted, enclosed fluidic chamber consisting of a variety of materials. The HV capability of the exciter chip allows the generated DEP forces to penetrate into the enclosed chamber region and an adjustable voltage amplitude can accommodate a variety of chamber floor thicknesses. This demonstration exciter chip has a 32 x 32 array of nominally 100 V electrode drivers that are individually programmable at each time point in the procedure to either of two phases: 0deg and 180deg with respect to the reference clock. For this demonstration chip, while operating the electrodes with a 100-V peak-to-peak periodic waveform, the maximum HV electrode waveform frequency is about 200 Hz; and standard 5-V CMOS logic data communication rate is variable up to 250 kHz. This HV demonstration chip is fabricated in a 130-V 1.0-mum SOI CMOS fabrication technology, dissipates a maximum of 1.87 W, and is about 10.4 mm x 8.2 mm.
Clozapine Effects on Positive and Negative Symptoms (1994)

Fifteen DSM-III-R diagnosed schizophrenics characterized by long-term neuroleptic nonresponse and significant negative symptoms were evaluated with the Positive and Negative Syndrome Scale, a well-operationalized measure of psychopathology, on a baseline neuroleptic and weekly thereafter across 26 weeks of clozapine treatment in order to explore clozapine's effect on other domains of schizophrenic psychopathology beyond its effect on positive symptoms. Mean differences from baseline indicated significant improvement on positive, negative, cognitive, excitement, and depression subscales after 12 weeks. Improvement observed after 12 weeks of clozapine treatment reliably predicted scores observed at week 26. There were no further significant improvements on any symptom profile, including positive and negative symptoms, in this long-term, nonresponder group between weeks 12 and 26. Overall, clozapine proved to affect a broad spectrum of discrete and nonoverlapping domains of psychopathology in this schizophrenic sample.
A new method of evaluating attachment representations in young school-age children: The Manchester Child Attachment Story Task (2000)

We describe a new instrument, using a doll-play vignette completion method, which applies concepts and methodologies from infant and adult attachment research to enable identification and detailed classification of internal representations of attachment relationships in young school-age children. Validation of the Manchester Child Attachment Story Task (MCAST) in a normal population (N = 53) shows good interrater reliability and content validity. Patterns of attachment representation identified show stability over time. Comparisons are made with existing methodologies, and potential applications of the instrument and directions for future research are discussed.
A Comparative Evaluation of Concrete Reinforced with Straight Steel Fibers and Fibers with Deformed Ends Glued Together into Bundles (1980)

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Sugar Binding to Na+/Glucose Cotransporters Is Determined by the Carboxyl-terminal Half of the Protein (1996)

d-Glucose is absorbed across the proximal tubule of the kidney by two Na+/glucose cotransporters (SGLT1 and SGLT2). The low affinity SGLT2 is expressed in the S1 and S2 segments, has a Na+:glucose coupling ratio of 1, a K0.5 for sugar of approximately 2 mM, and a K0.5 for Na+ of approximately 1 mM. The high affinity SGLT1, found in the S3 segment, has a coupling ratio of 2, and K0.5 for sugar and Na+ of approximately 0.2 and 5 mM, respectively. We have constructed a chimeric protein consisting of amino acids 1-380 of porcine SGLT2 and amino acids 381-662 of porcine SGLT1. The chimera was expressed in Xenopus oocytes, and steady-state kinetics were characterized by a two-electrode voltage-clamp. The K0.5 for alpha-methyl-d-glucopyranoside (0.2 mM) was similar to that for SGLT1, and like SGLT1 the chimera transported D-galactose and 3-O-methylglucose. In contrast, SGLT2 transports poorly D-galactose and excludes 3-O-methylglucose. The apparent K0.5Na was 3.5 mM (at -150 mV), and the Hill coefficient ranged between 0.8 and 1.5. We conclude that recognition/transport of organic substrate is mediated by interactions distal to amino acid 380, while cation binding is determined by interactions arising from the amino- and carboxyl-terminal halves of the transporters. Surprisingly, the chimera transported alpha-phenyl derivatives of D-glucose as well as the inhibitors of sugar transport: phlorizin, deoxyphlorizin, and beta-D-glucopyranosylphenyl isothiocyanate are transported with high affinity (K0.5 for phlorizin was 5 microM). Thus, the pocket for organic substrate binding is increased from 10 x 5 x 5 (A) for SGLT1 to 11 x 18 x 5 (A) for the chimera.
Functional Models of [Fe—S] Nitrosyl Proteins. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Combined 3‐D interpretation of airborne, surface, and borehole vector magnetics at the McConnell Nickel deposit (1997)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1997Combined 3‐D interpretation of airborne, surface, and borehole vector magnetics at the McConnell Nickel depositAuthors: Edna L. MuellerWilliam A. MorrisPatrick G. KilleenSteve BalchEdna L. MuellerMcMaster University, William A. MorrisMcMaster University, Patrick G. KilleenGeological Survey of Canada, and Steve BalchINCO Limitedhttps://doi.org/10.1190/1.1885952 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1885952FiguresReferencesRelatedDetailsCited by3D magnetization inversion using fuzzy c-means clustering with application to geology differentiationYaoguo Li and Jiajia Sun11 July 2016 | GEOPHYSICS, Vol. 81, No. 5Directional location of buried objects using three-component magnetic borehole data demonstrated for the case of a drill string11 April 2016 | Geophysical Journal International, Vol. 205, No. 33D magnetic inversion of 3D magnetic dataset of the Canadian Malartic mineMichel Chouteau and Pejman Shamsipour22 April 2015Application of 3D magnetic amplitude inversion to iron oxide-copper-gold deposits at low magnetic latitudes: A case study from Carajás Mineral Province, BrazilMarcelo Leão-Santos, Yaoguo Li, and Roberto Moraes4 February 2015 | GEOPHYSICS, Vol. 80, No. 2Tools and Techniques: Magnetic Methods of Exploration – Principles and AlgorithmsInversion of magnetic anomaly on rugged observation surface in the presence of strong remanent magnetizationShu-Ling Li and Yaoguo Li17 February 2014 | GEOPHYSICS, Vol. 79, No. 2Crosshole seismic imaging for sulfide orebody delineation near Sudbury, Ontario, CanadaJoe Wong7 February 2012 | GEOPHYSICS, Vol. 65, No. 6 SEG Technical Program Expanded Abstracts 1997ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1997 Pages: 2067 publication data© 1997 Copyright © 1997 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 10 Feb 2005 CITATION INFORMATION Edna L. Mueller, William A. Morris, Patrick G. Killeen, and Steve Balch, (1997), "Combined 3‐D interpretation of airborne, surface, and borehole vector magnetics at the McConnell Nickel deposit," SEG Technical Program Expanded Abstracts : 523-526. https://doi.org/10.1190/1.1885952 Plain-Language Summary PDF DownloadLoading ...
Dichotomy in Health Care Policy (1993)

I found the editorial by Singer and Lowy 1 very thought provoking with many interesting facts as well as ideas. However, it has been my experience that patients and their families are unwilling to take the initiative despite careful discussion in choosing to address an advanced health care directive. It is now nationwide policy in the United States to provide every patient who enters the hospital with information concerning advanced life and health care directives. It has been my experience that these are not very helpful in the care of the patient should he/she reach a critical illness. It is also my thinking that the proposed 5 billion dollars saved, at the authors' low-end estimation, is still probably an overestimation of what it would, in fact, save us. 2 The patients who receive care in the intensive care units certainly comprise a large bulk of high technology, high expense medical
Bush lives - bush futures: The economic future of Australia's remote rural heritage (2001)

Two centuries of European settlement has dramatically and fundamentally altered the cultural landscape of Australia. Colonists drawn from all parts of the world considered it terra nullius - an empty land of limitless opportunity, unaware of the delicate ecological relationship which had been forged by its. Aboriginal owners.
Simplifying Neural Networks by Soft Weight-Sharing (1992)

One way of simplifying neural networks so they generalize better is to add an extra term to the error function that will penalize complexity. Simple versions of this approach include penalizing the sum of the squares of the weights or penalizing the number of nonzero weights. We propose a more complicated penalty term in which the distribution of weight values is modeled as a mixture of multiple gaussians. A set of weights is simple if the weights have high probability density under the mixture model. This can be achieved by clustering the weights into subsets with the weights in each cluster having very similar values. Since we do not know the appropriate means or variances of the clusters in advance, we allow the parameters of the mixture model to adapt at the same time as the network learns. Simulations on two different problems demonstrate that this complexity term is more effective than previous complexity terms.
Isolation and characterization of β-act in gene of carp ( <i>Cyprinus carpio</i> ) (1990)

A beta-actin gene of carp (Cyprinus carpio) was isolated from a genomic EMBL3 library. The nucleotide sequence of the gene indicates six exons spanning 3.6 kb. Southern blot hybridization of restriction endonuclease digests of carp genomic DNA indicate that there are two copies of the beta-actin isotype and several other species of actin genes. The transcriptional start site is 85 bp and 24 bp downstream respectively from consensus CCAAT and TATA promoter elements. The organization of the carp beta-actin gene is identical to that of chicken, human, and rat genes in terms of size, exon/intron locations and junctions and in having a translationally silent first exon. The fish gene is 90% and 99% conserved at the nucleotide and amino acid levels, respectively, with land vertebrate beta-actin genes. Northern blot analysis of beta-actin gene expression indicated that the gene is highly expressed in brain, less so in muscle, and much less so in liver cells. The putative beta-actin proximal promoter of carp, identified by the conservation of known actin regulatory sequences, is transcriptionally active in both mammalian and piscine cells.
How to Do Everything with Your Palm Handheld (2000)

From the Publisher:
Learn to use all Palm OS handheld devices, including the Palm VII handheld, the Handspring Visor, and Qualcomm pdQ smartphone with this friendly, solutions-oriented guide. 
Book rights: McGraw-Hill, the publisher of this eBook, is granting readers the right to print this book as well as the right to lend/give this eBook to other Adobe Acrobat eBook Plus Reader users.
Printing: Users can print eBook pages as needed. This is an especially useful feature for business people. To print, click on the menu button in the Acrobat eBook Reader and select the print option. 
Lending/Giving We currently have two ways to lend or give a book: you can beam it to a computer if both have infrared ports, or you can send it to a computer on your network. To lend a book to someone else, go to the Library, click a book. Click the Menu button and then click Lend/Give to display the Lend/Give dialog box. Choose a loan period or click Give. To send the book over an infrared connection, click Beam. To send the book to a computer on the network, enter the computer name in the Send To box and click Send. You can either lend the book or give it away. Like a paper book, there is only ever one working copy. Once the lending period expires, you get your rights back and you can re-read the book or lend it again. Of course, if you give it away, it's gone for good (unless the recipient gives it back). 
Listen to your eBooks
Users have the ability to listen to the spoken text of this book. Simply click the Read Aloud button in the Adobe eBook Reader. A control panel appears at the bottom of the display area where you can pause, continue, or stop the spoken text. Please note:This feature is only available on Windows 2000 machines.
Compounding of Thermoplastic Starch with Twin‐screw Extruders (1991)

Abstract The compounding of thermoplastic starch can be regarded as a combined process consisting of extrusion cooking and plastic compounding. The quality of the product is determined largely by the degree of mechanical shear, temperature and water content. These parameters can be influenced both by the machine system and the various components of a machine. These include infinitely adjustable throttle systems and continuous condensation and evaporation equipment. On account of the fact that the starch pellets are sometimes soluble in water, the type of pelletizing is also very important. A product quality which has been optimized can be reproduced every day by means of automatic systems. Some examples of on‐line quality control systems are shown.
Copper‐coated microsprayer interface for on‐line sheathless capillary electrophoresis electrospray mass spectrometry of carbohydrates (2006)

A sturdy home-built sheathless CE/ESI-QTOF-MS system was developed and optimized for carbohydrate analysis. The interface and employed methodology provided a simple analytical solution to laborious CE/MS interfacing methods and to problems in characterization of complex carbohydrate mixtures that require high-resolution separation of the components. The CE/ESI interface, feasible in any MS laboratory, consists of a one-piece CE column having the CE terminus in-laboratory shaped as a microsprayer and coated with copper. The CE microsprayer was inserted into an in-house made stainless steel clenching device and the whole assembly was mounted onto a quadrupole TOF mass spectrometer. The analytical potential of the interface in terms of suitability, microsprayer performance, copper coat durability, ionization efficiency, spray stability, and sensitivity was tested first on a simple mixture of standard saccharides, which were separated, resolved, and detected with high separation efficiency. The approach was next assessed for the screening of a biological sample, a complex mixture of O-glycosylated sialylated amino acids from urine of a patient suffering from Schindler disease. Preliminary data allow this method to be considered as one of general applicability in structural glycobiology and glycomics and easy to be implemented for proteomic surveys as well.
A thermodynamic study of the binding of linear and cyclic oligosaccharides to the maltodextrin-binding protein of Escherichia coli (1998)

Isothermal titration calorimetric (ITC) studies over a range of temperatures of the binding of maltose, maltotriose, maltotetraose and beta-cyclodextrin to the maltodextrin-binding protein (MBP) of Escherichia coli are reported. The binding constants of maltose, maltotriose and beta-cyclodextrin are not very different, namely 8.7 x 10(5), 13.0 x 10(5) and 2.55 x 10(5) M-1, respectively at 25 degrees C. The calorimetric data obtained with maltotetraose cannot be interpreted in terms of a definite binding constant. The binding of maltose and maltotriose is endothermic with a large entropy increase while that of beta-cyclodextrin is exothermic, with a smaller entropy increase. The binding of maltotetraose was endothermic or exothermic depending on the temperature.