gebhart/patrepeval huggingface dataset:
Application of Neural Network Model to Forecast Short-Term Pavement Crack Condition: Florida Case Study (2001)

Certain highway agencies such as the Florida Department of Transportation use the crack index (CI) to enumerate pavement cracking and determine the rehabilitation priorities. Thus, accurate forecasting of CI is essential for pavement rehabilitation budgeting. Currently, mechanistic-empirical and purely empirical models are popular tools for forecasting pavement cracking. However, with a large data dimension, it is difficult to select appropriate mathematical function forms for the above models. This paper summarizes the results obtained from a case study in which single-year and multiyear back-propagation neural network (BPNN) models were developed to forecast accurately the short-term time variation of CIs of Florida's highway network. The BPNN models exhibited a remarkable ability of learning the historical crack progression trend from the CI database and accurately forecasting future CI values. Then, the BPNN model was validated by comparing the forecasted CIs with measured CI data for the year 1998. Finally, the BPNN model results were compared to those of a commonly used autoregressive model and the BPNN model was seen to be certainly more accurate than the autoregressive model. Hence the BPNN models can be expected to make a significant impact on the efficiency of rehabilitation budget planning in particular and pavement management systems in general.
Assembly of CS1 Pili: the Role of Specific Residues of the Major Pilin, CooA (2005)

CS1 pili are important virulence factors of enterotoxigenic Escherichia coli strains associated with human diarrheal disease. They are the prototype for a family of pili that share extensive sequence similarity among their structural and assembly proteins. Only four linked genes, cooB, cooA, cooC, and cooD, are required to produce CS1 pili in E. coli K-12. To identify amino acids important for the function of the major pilin CooA, we used alanine substitution mutagenesis targeting conserved residues in the N and C termini of the protein. To test function, we examined cooA mutants for the ability to agglutinate bovine erythrocytes. Each hemagglutination-negative (HA(-)) cooA mutant was examined to identify its assembly pathway defect. CooA has been shown to be degraded in the absence of CooB (K. Voegele, H. Sakellaris, and J. R. Scott, Proc. Natl. Acad. Sci. USA 94:13257-13261, 1997). We found several HA(-) cooA mutants that produced no detectable CooA, suggesting that recognition by CooB is mediated by residues in both the N and C termini of CooA. In addition, we found that alanine substitution for some of the conserved residues in the C-terminal motif "AGxYxG(x(6))T," which is found in all subunits of this pilus family, had no effect on pilus formation. However, alanine substitution for some of the alternating hydrophobic residues within this motif prevented CooA from interacting with CooD, which serves as both the tip adhesin and nucleation protein for pilus formation. Thus, it appears that some, but not all, of the residues in both the N and C termini of CooA play a critical role in the intermolecular interactions of the major pilin with the other structural and assembly proteins. We anticipate that the results obtained here for CS1 pili in enterotoxigenic E. coli will help develop an understanding of the pilus assembly pathway used by CS1 family members in several important human pathogens.
Inter-Vehicle Communication Protocol Design for a Yielding Decision at an Unsignalized Intersection and Evaluation of the Protocol Using Radio Control Cars Equipped with Raspberry Pi (2019)

The Japanese government aims to introduce self-driven vehicles by 2020 to reduce the number of accidents and traffic jams. Various methods have been proposed for traffic control at accident-prone intersections to achieve safe and efficient self-driving. Most of them require roadside units to identify and control vehicles. However, it is difficult to install roadside units at all intersections. This paper proposes an inter-vehicle communication protocol that enables vehicles to transmit their vehicle information and moving direction information to nearby vehicles. Vehicles identify nearby vehicles using images captured by vehicle-mounted cameras. These arrangements make it possible for vehicles to exchange yielding intention at an unsignalized intersection without using a roadside unit. To evaluate the operations of the proposed protocol, we implemented the protocol in Raspberry Pi computers, which were connected to cameras and mounted on radio control cars and conducted experiments. The experiments simulated an unsignalized intersection where both self-driven and human-driven vehicles were present. The vehicle that had sent a yielding request identified the yielding vehicle by recognizing the colour of each radio control car, which was part of the vehicle information, from the image captured by its camera. We measured a series of time needed to complete the yielding sequence and evaluated the validity of yielding decisions.
Using the Acropora digitifera genome to understand coral responses to environmental change (2011)

Despite the enormous ecological and economic importance of coral reefs, the keystone organisms in their establishment, the scleractinian corals, increasingly face a range of anthropogenic challenges including ocean acidification and seawater temperature rise. To understand better the molecular mechanisms underlying coral biology, here we decoded the approximately 420-megabase genome of Acropora digitifera using next-generation sequencing technology. This genome contains approximately 23,700 gene models. Molecular phylogenetics indicate that the coral and the sea anemone Nematostella vectensis diverged approximately 500 million years ago, considerably earlier than the time over which modern corals are represented in the fossil record (∼240 million years ago). Despite the long evolutionary history of the endosymbiosis, no evidence was found for horizontal transfer of genes from symbiont to host. However, unlike several other corals, Acropora seems to lack an enzyme essential for cysteine biosynthesis, implying dependency of this coral on its symbionts for this amino acid. Corals inhabit environments where they are frequently exposed to high levels of solar radiation, and analysis of the Acropora genome data indicates that the coral host can independently carry out de novo synthesis of mycosporine-like amino acids, which are potent ultraviolet-protective compounds. In addition, the coral innate immunity repertoire is notably more complex than that of the sea anemone, indicating that some of these genes may have roles in symbiosis or coloniality. A number of genes with putative roles in calcification were identified, and several of these are restricted to corals. The coral genome provides a platform for understanding the molecular basis of symbiosis and responses to environmental changes.
Parametric design of pressure-relieving foot orthosis using statistics-based finite element method (2007)

Custom-molded foot orthoses are frequently prescribed in routine clinical practice to prevent or treat plantar ulcers in diabetes by reducing the peak plantar pressure. However, the design and fabrication of foot orthosis vary among clinical practitioners and manufacturers. Moreover, little information about the parametric effect of different combinations of design factors is available. As an alternative to the experimental approach, therefore, computational models of the foot and footwear can provide efficient evaluations of different combinations of structural and material design factors on plantar pressure distribution. In this study, a combined finite element and Taguchi method was used to identify the sensitivity of five design factors (arch type, insole and midsole thickness, insole and midsole stiffness) of foot orthosis on peak plantar pressure relief. From the FE predictions, the custom-molded shape was found to be the most important design factor in reducing peak plantar pressure. Besides the use of an arch-conforming foot orthosis, the insole stiffness was found to be the second most important factor for peak pressure reduction. Other design factors, such as insole thickness, midsole stiffness and midsole thickness, contributed to less important roles in peak pressure reduction in the given order. The statistics-based FE method was found to be an effective approach in evaluating and optimizing the design of foot orthosis.
A systematic approach to the management of cholestatic pruritus in primary biliary cirrhosis (2015)

Pruritus (itch) is an important symptom of primary biliary cirrhosis (PBC), an archetypal cholestatic liver disease. Cholestatic pruritus can be a debilitating symptom causing significant deterioration in patients' quality of life. Effective management of pruritus in PBC involves awareness among clinicians to adequately assess its severity, and treatment with specific drug therapies in line with current practice guidelines. In PBC, antipruritic drugs are not universally effective and/or have significant side effects, and despite best efforts with various combinations of drugs, some patients remain significantly symptomatic, eventually opting for invasive or experimental treatments. Therefore, there is a clear unmet need for better alternative treatments for patients with refractory or intractable cholestatic pruritus. Recent advances in the understanding of pathogenesis of cholestatic pruritus and bile acid physiology have raised hopes for novel therapies, some of which are currently under trial. In this review, we aim to provide a practical guide to the management of this important and complex problem, discussing current knowledge and recent advances in the pathogenesis, summarise the evidence base for available therapeutic approaches and update potential novel future therapies for the management of pruritus in PBC.
Enzyme‐Mediated Controlled Release Systems by Anchoring Peptide Sequences on Mesoporous Silica Supports (2011)

Gated community: Peptides anchored to the surface of silica mesoporous supports by a valid procedure act as gatekeepers. In this way, “zero release” supports that selectively deliver the cargo in the presence of a suitable peptidase are obtained (see picture, red spheres: cargo, colored chains: peptides).
[A case of chronic hypersensitivity pneumonia with elevation of serum SP-D and KL-6]. (2002)

A 73-year-old woman suffering from dyspnea on effort and chronic cough was admitted to our hospital. Chest computed tomography disclosed ground-glass opacities, irregular linear opacities and honeycombing distributed predominantly in the subpleural area. The serum levels of SP-D and KL-6 rose to 889 ng/ml, 1,755 U/ml, respectively. These findings indicated idiopathic pulmonary fibrosis. However, the number of lymphocytes and the CD4/CD8 ratio in the BAL fluid were elevated. Transbronchial lung biopsy specimens demonstrated alveolitis with granuloma formation. The evidence that she had lived in a house with a heavy fungal growth and that tests of precipitation in response to Penicillium corylophilum were positive confirmations of a diagnosis of chronic hypersensitivity pneumonia.
Continuous monitoring of intracranial pressure with a miniaturized fiberoptic device (1987)

A No. 4 French fiberoptic catheter initially developed as an intravascular pressure sensor was incorporated into a system to be used as an intracranial pressure (ICP) monitor. Initially, a series of acute and chronic animal experiments carried out in the rabbit and pig, respectively, demonstrated the reliability and safety of the device. Subsequently, this new monitor was compared to a concurrently functioning ICP monitor in 15 adult and five pediatric patients. This clinical experience also confirmed the safety, accuracy, and reliability of the device. Since these initial studies, this monitor has been used to routinely measure ICP in a large number of adult and pediatric patients. The monitor has functioned well, and there have been no complications related to its use except for an occasional problem with breakage of the optic fiber as a result of patient movement or nursing maneuvers, which has been easily corrected by replacement of the probe. As nursing personnel and ancillary services have become familiar with this new monitor, breakage has not been a problem. This new device can be placed into the ventricular system, the brain parenchyma, or the subdural space, and appears to offer substantial advantages over other monitors presently in use.
A Circuit for the Analysis of Geiger-Counter Pulses (1935)

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UTRdb: a specialized database of 5' and 3' untranslated regions of eukaryotic mRNAs (1999)

The 5′ and 3′ untranslated regions of eukaryotic mRNAs may play a crucial role in the regulation of gene expression controlling mRNA localization, stability and translational efficiency. For this reason we developed UTRdb (http://bigarea.area.ba.cnr.it:8000/Biowww/#UTRdb), a specialized database of 5′ and 3′ untranslated sequences of eukaryotic mRNAs cleaned from redundancy. UTRdb entries are enriched with specialized information not present in the primary databases including the presence of nucleotide sequence patterns already demonstrated by experimental analysis to have some functional role. All these patterns have been collected in the UTRsite database so that it is possible to search any input sequence for the presence of annotated functional motifs. Furthermore, UTRdb entries have been annotated for the presence of repetitive elements.
4 × 4 optical-gate matrix switch (1985)

An optical gate-based matrix switch is proposed and a switching function in a 4 × 4 experimental switch is demonstrated. The experimental switch is composed of fiber-type splitters, a lantham-modified lead zirconate-titanate solid solution (PLZT) optical-gate array, and fiber-type combiners. The switch has a broad bandwidth of 400 Mbit/s for nonreturn-to-zero (NRZ) optical signal transmission. A possible maximum matrix size is discussed theoretically based on optical power level and optical crosstalk.
Recent progress on the structure separation of single-wall carbon nanotubes (2017)

The mass production of single-structure, single-wall carbon nanotubes (SWCNTs) with identical properties is critical for their basic research and technical applications in the fields of electronics, optics and optoelectronics. Great efforts have been made to control the structures of SWCNTs since their discovery. Recently, the structure separation of SWCNTs has been making great progress. Various solution-sorting methods have been developed to achieve not only the separation of metallic and semiconducting species, but also the sorting of distinct (n, m) single-chirality species and even their enantiomers. This progress would dramatically accelerate the application of SWCNTs in the next-generation electronic devices. Here, we review the recent progress in the structure sorting of SWCNTs and outline the challenges and prospects of the structure separation of SWCNTs.
A highly practical modified LOCOS isolation technology for the 256 Mbit DRAM (1994)

We have developed a modified LOCOS isolation technology for the 256 Mbit DRAM. This novel Poly-Si Spacer LOCOS (PSL) isolation has been applied to build a 16 Mbit density DRAM with 256 Mbit (0.3 /spl mu/m) design rules. With the PSL isolation process, low bird's beak encroachment, good vertical profile, clear definition of the active and field boundaries, high punchthrough voltage, and low leakage current have been achieved by simple fabrication processes.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Multi-functional fluorescent carbon dots with antibacterial and gene delivery properties (2015)

Dual-functionality carbon dots with both anti-microbial and gene transfection abilities were developed and their properties elaborated in this paper.
[A resource investigation and commodity identification of Fructus Amomi]. (2001)

Resource investigation and commodity identification were carried out for 28 samples of Fructus Amomi collected from 7 provinces. The results showed that Fructus Amomi used currently were mainly from the dried ripe-fruit of Amomum villosum, A. villosum var. xanthioides or A. longiligulare. Fructus Amomi in market is nainly A. villosum which comes from Yunnan and Guangdong province.
An overview on glutathione in versus non-conventional yeasts (2002)

Glutathione (GSH: L-gamma-glutamyl-L-cysteinylglycine) is present in high concentrations up to 10 mM in yeast cells. Its very low redox potential (E'(o)=-240 mV for thiol disulfide exchange) gives this tripeptide the properties of a cellular redox buffer. In Saccharomyces cerevisiae and non-conventional yeasts (NCY), GSH may be involved in basic cellular functions such as the maintenance of mitochondrial and membrane integrity. GSH also assumes pivotal roles in (i) response to sulfur and nitrogen starvation; (ii) detoxification of endogenous toxic metabolites, such as excess formaldehyde produced during the growth of the methylotrophic yeasts Hansenula polymorpha, Candida boidinii and Kloeckera sp.; (iii) protection against oxidative stress provoked by exposure of the cells to reactive oxygen species including peroxides and hydroperoxides; (iv) detoxification of xenobiotics such as halogenated aromatics, alkylating agents and arsenite; (v) resistance to heavy-metal stress exemplified by the responses of S. cerevisiae and Schizosaccharomyces pombe to cadmium salts; (vi) yeast<-->mycelium transition in Candida and Aureobasidium sp.
AN INTEGRATED MICROFLUIDIC DEVICE FOR QUANTITATIVE MEASUREMENT OF HEPATOCELLULAR CARCINOMA (HCC) BIOMARKERS IN WHOLE BLOOD SAMPLES (2011)

We developed a novel microfluidic device that can extract plasma from whole blood and can be integrated with the isotachophoresis (ITP)-capillary electrophoresis (CE) platform. This device integrated a filter membrane followed by a sedimentation channel, in which we can get 1-2uL of plasma within 5 minutes. We also demonstrated an integrated microfluidic device which achieves blood separation and an ITP -CE immunoassay. Des-gamma-carboxy prothrombin (DCP), a HCC biomarker, was used as a model analyte in blood. We can detect the DCP spiked into whole blood at 4.36ng/mL.
Automated Topographic Segmentation and Transit Time Estimation in Endoscopic Capsule Exams (2008)

Endoscopic capsule is a recent medical technology with important clinical benefits but suffering from a practical handicap: long exam annotation times. This paper proposes and compares two approaches (Bayesian and support vector machines) that can be used to segment the gastrointestinal tract into its four major topographic areas, allowing the automatic estimation of the clinically relevant gastric and intestinal sections and corresponding transit times. According to medical specialists, this can reduce exam annotation times by up to 12% (15 min). This automatic tool has been integrated into our CapView annotation software that is currently being used by three medical institutions.
Instrumentation for osmometry (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInstrumentation for osmometryPeter F. Lott and Frank Millich Cite this: J. Chem. Educ. 1966, 43, 3, A191Publication Date (Print):March 1, 1966Publication History Received3 August 2009Published online1 March 1966Published inissue 1 March 1966https://doi.org/10.1021/ed043pA191Request reuse permissionsArticle Views149Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (5 MB) Get e-Alertsclose Get e-Alerts
Solving Complex Logistics Problems with Multi-Artificial Intelligent System (2009)

The economy, which has become more information intensive, more global and more technologically dependent, is undergoing dramatic changes. The role of logistics is also becoming more and more important. In logistics, the objective of service providers is to fulfill all customers' demands while adapting to the dynamic changes of logistics networks so as to achieve a higher degree of customer satisfaction and therefore a higher return on investment. In order to provide high quality service, knowledge and information sharing among departments becomes a must in this fast changing market environment. In particular, artificial intelligence (AI) technologies have achieved significant attention for enhancing the agility of supply chain management, as well as logistics operations. In this research, a multi-artificial intelligence system, named Integrated Intelligent Logistics System (IILS) is proposed. The objective of IILS is to provide quality logistics solutions to achieve high levels of service performance in the logistics industry. The new feature of this agile intelligence system is characterized by the incorporation of intelligence modules through the capabilities of the case-based reasoning, multi-agent, fuzzy logic and artificial neural networks, achieving the optimization of the performance of organizations.
Early, Accurate and Fast Yield Estimation through Monte Carlo-Alternative Probabilistic Behavioral Analog System Simulations (2006)

Monte Carlo analysis has so far been the corner stone for analog statistical simulations. Fast and accurate simulations are necessary for stringent time-to-market, design for manufacturability and yield concerns in the analog domain. Although Monte Carlo attains accuracy, it does so with a sacrifice in run-time for analog simulations. In this paper, we propose a fast and accurate probabilistic simulation method alternative to Monte Carlo using deterministic sampling and weight propagation. We furthermore propose accuracy improvement algorithms and a fast yield calculation method. The proposed method shows accuracy improvement combined with a 100-fold reduction in run-time with respect to a 1000-sample Monte Carlo analysis