gebhart/patrepeval huggingface dataset:
Coilable Crystalline Fiber (CCF) Lasers and their Scalability (2014)

Abstract : Conventional fiber lasers offer excellent beam quality and efficiency for high power lasers, but their composition (glass) poses significant disadvantages in pump absorption, gain, and thermal conductivity. All-crystalline fiber lasers, particularly if double-clad, would improve all these properties, greatly facilitating power scaling. Yet, progress in fabricating all-crystalline fibers has been limited thus far. The U.S. Army Research Laboratory (ARL) in partnership with Onyx Optics studied fully crystalline waveguides fabricated using current bonding techniques, with geometry similar to conventional double-clad fibers. We measured refractive indices to determine the parameters for erbium- or thulium-doped YAG (Y3Al5O12)/YAG/spinel (MgAl2O4) double-clad waveguides with a single-mode core. We also investigated YAG doped with ytterbium as an inner cladding material, as its index can be adjusted to facilitate design of a single-mode core with large area. We characterized the thermal conductivity of nominally polycrystalline samples of each material. We performed laser experiments on both single- and double-clad Er:YAG cores of different sizes, and have obtained world s-first and world-record laser performance. This includes 25-W continuous wave (CW) output due to cladding-pumping of what we believe is the first truly double-clad all-crystalline YAG waveguide laser, and a record room-temperature slope efficiency (with respect to absorbed pump) of nearly 93 % with excellent beam quality from a core-pumped waveguide.
New Developments in Anti-Platelet Therapies Potential Use of CD39/Vascular ATP Diphosphohydrolase in Thrombotic Disorders (2000)

Abnormal platelet reactivity has been linked to unstable angina, myocardial infarction, post angioplasty stenosis, cerebral ischemia, thrombotic stroke and a variety of inflammatory vascular disorders associated with transplantation. Drugs that inhibit blood coagulation, promote fibrinolysis or block platelet activation are important therapeutic agents in cardiovascular medicine. However, many of the current antiplatelet modalities are nonspecific, ineffective or associated with severe side effects that limit their usefulness. In this article, we discuss some basic aspects of platelet pathophysiology to illustrate the importance of ADP stimulation and signaling in platelet activation. CD39, the ATP diphosphohydrolase (ATPDase) expressed on quiescent vascular endothelium, modulates platelet purinoreceptor activity by the sequential hydrolysis of extracellular ATP or ADP directly to AMP. This thromboregulatory potential of CD39 has been recently demonstrated by the generation of mutant mice with disruption of the gene, and by a series of experiments where high level ATPDase expression has been attained by adenoviral vectors in the injured vasculature. Systemic administration of soluble derivatives of CD39 or targeted expression of the native protein to sites of vascular injury may have future therapeutic application.
Annotating Students’ Understanding of Science Concepts (2008)

This paper summarizes the annotation of fine-grained entailment relationships in the context of student answers to science assessment questions. We annotated a corpus of 15,357 answer pairs with 145,911 fine-grained entailment relationships. We provide the rationale for such fine-grained analysis and discuss its perceived benefits to an Intelligent Tutoring System. The corpus also has potential applications in other areas, such as question answering and multi-document summarization. Annotators achieved 86.2 % inter-annotator agreement (Kappa=0.728, corresponding to substantial agreement) annotating the fine-grained facets of reference answers with regard to understanding expressed in student answers and labeling from one of five possible detailed relationship categories. The corpus described in this paper, which is the only one providing such detailed entailment annotations, is available as a public resource for the research community. The corpus is expected to enable application development, not only for intelligent tutoring systems, but also for general textual entailment applications, that is currently not practical. 1.
Baroreceptor stimulation alters cortical activity (1993)

The arterial baroreceptors constitute an essential sensory link for the short-term regulation of blood pressure and may also influence higher cortical function. The present study was undertaken to evaluate previous reports of such a cortical influence under conditions of psychologically controlled, mechanical baroreceptor stimulation. This control was achieved by use of PRES (phase-related external suction), a modified neck suction technique. PRES applies short suction bursts that have a different impact on baroreceptors depending on their timing within the cardiac cycle and has the advantage that subjects cannot easily discriminate between conditions of stimulation and inhibition. Electroencephalograms were recorded from 22 subjects during PRES manipulations. A surface-negative shift of about 10 microV developed during the cuff manipulations. Over frontal-central regions, this shift was smaller during baroreceptor stimulation than during inhibition. These data provide support for the proposal that baroreceptor activation influences cortical activity.
A Distributed Fuel Cell Based Generation and Compensation System to Improve Power Quality (2006)

A small single-phase fuel cell based energy generation and compensation system is proposed in this paper. The power conditioning unit of the system comprises a grid-interfacing inverter and a three-port bidirectional converter which connects a fuel cell and supercapacitor to the inverter. The system can operate in both island and grid-connected modes. By taking advantage of the transient storage capability offered by the supercapacitor, the function of reactive power compensation is integrated into the system. Simultaneously, the inverter is operated as a shunt active power filter and, by means of a proposed control strategy, compensates for reactive and harmonic current demanded by local loads. The system is suitable for residential applications and can improve the quality of a weak power grid. Simulation and experimental results show the validity and feasibility of the proposed system
Implementation of a safety instrumented system (2007)

We have developed the ProSafe-RS Safety System as a core safety instrumented systems of Yokogawa. This system complies with safety integrity level 3 (SIL3) of the IEC61508, and has been certified by a third-party certification body as conforming to the standard. In addition, it has high availability and nice features so that it provides comprehensive solutions to users who implement integration with process control systems. The main feature of the ProSafe-RS hardware is the application of dual microprocessor technology, not only to the processor module, but also to the I/O module. This paper describes the technologies to achieve high safety integrity level such as dual redundant technologies and diagnostics.
Channel feedback quantization methods for MISO and MIMO systems (2005)

We investigate the quantization of multiple antenna channel to feed back through a low-rate feedback channel. Specifically, for multiple-input single-output (MISO) systems, we propose a new design criterion and the corresponding design algorithm for quantization of the random beamforming vector. For multiple-input multiple-output (MIMO) channels, which have multiple orthonormal vectors as channel spatial information for quantization, a matrix factorization method is proposed which provides a way to exploit the geometrical structure of orthonormality while quantizing the spatial information matrix. Results show that the quantization bit allocation over multiple spatial channels has a critical effect on the performance, and that the optimum bit allocation depends on the operating transmit power of the system.
skINsight Lessons in Reflectance Confocal Microscopy (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
[Experimental study of three dimensional navigation assisted spinal surgery by multi-segment registration technology based on structured light scanning]. (2011)

With a high accuracy and a perturbation resistance, a combination of pre-registration and multi-segment registration algorithm based on structured light scanning is competent for the registration of CT scanning data and structured light scanning data.
Wirksamkeit eines oralen Beruhigungsmittels auf das Verhalten und die zootechnischen Leistungen von Mastbullen der Weiß‐Blauen Belgischen Rasse (1991)

This trial was conducted with 22 Belgian White and Blue double-muscled cattle (body weight: 241.5 +/- 6.2 kg; age: 7 months). Two similar groups were constituted: a group of bulls which were treated with potassium bromide (BT; n = 11) and another one which remained untreated (UT; n = 11). The treatment (736 mg potassium bromide/kg feed dry matter) was stopped 60 days before the slaughtering day. The treatment with potassium bromide induced a significant reduction in the rear engagements during the whole trial period (221 days), in direct attacks during the period A (from day 0 to day 53) and in side-on attacks during the period B (from day 54 to day 167). The daily weight gains, calculated for the whole trial period, were not significantly different between the two groups. Feed utilization was lower in treated bulls. During the period C (from day 168 to day 221), the sedative potency of potassium bromide seemed to be weaker than during the periods A and B. This might be due to the habituation to potassium bromide. On the basis of these results, we can conclude that the frequency of rear engagements and, during a restricted period of fattening, the frequencies of side and direct attacks are significantly reduced when potassium bromide (736 mg/kg feed dry matter) is used. The time spent for hay intake, the frequency of water intake (even if the time consumed at the drinking trough was the same) was reduced and the time during which the bulls were standing was prolonged by bromide.
Rational design of cobalt–chromium layered double hydroxide as a highly efficient electrocatalyst for water oxidation (2016)

The design of a high performance, stable and cost-effective electrocatalyst for oxygen evolution is crucial for H<sub>2</sub> production from electrochemical water splitting.
Trans‐Esophageal Pacing (1983)

A new lead-electrode for trans-esophageal pacing of the human heart has been developed. The heart can be paced from the esophagus using currents of the same intensity as those for temporary pacing electrodes. The lead allows the electrodes to be positioned properly in the esophagus with a gastric balloon without use of additional equipment. Noninvasive atrial or ventricular pacing can thus be established quickly, even by non-specialized physicians. The method has been tested on a group of 13 healthy volunteers. Both atrial and ventricular pacing were performed without discomfort. The method opens new diagnostic and therapeutic possibilities with trans-esophageal pacing techniques.
Convective transport of macromolecules in gels (1999)

Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1999.
Mutations in B‐type natriuretic peptide mediating receptor‐A selectivity (1997)

Libraries of monovalent display-phage expressing mutant human B-type natriuretic peptide (hBNP) were used to identify variants that preferentially bind natriuretic peptide receptor-A (NPR-A) compared to receptor-C (NPR-C). Position 19 was a significant determinant of receptor specificity for hBNP display phage. The synthetic hBNP variant S19R had a 265-fold improved NPR-A binding over NPR-C, analogous to the atrial natriuretic peptide (ANP) specificity mutation G16R. Mutation of the last three residues of the hBNP disulfide ring, G23F/L24W/G25R, resulted in about 9-fold improved selectivity. The analogous mutations in ANP decreased NPR-A binding, suggesting divergence in the mechanism of NPR-A recognition.
Peptide-Mediated Immunosuppression (2005)

There is now a substantial body of data demonstrating the abilities of synthetic peptides and peptide analogues to inhibit the auto- and alloimmune response in vitro and in vivo. We have studied the immunomodulatory role of synthetic peptides derived from highly conserved regions of the class II MHC alpha chain. These MHC-derived peptides inhibit the rat, human, and mouse mixed lymphocyte response (MLR), proliferation to autoantigen, cytokine production, and cytolytic T lymphocyte (CTL) generation. Our studies demonstrated that the inhibitory effect of the MHC class II nonpolymorphic peptides is mediated through the induction of apoptosis in APCs via a nonclassic caspase-independent pathway. In addition, T lymphocytes initially stimulated in the presence of HLA-DQA1 are rendered hyporesponsive to subsequent stimuli. Immunomodulation by HLA-DQA1 was effective in vivo because it prevented both the priming and the effector function of primed allogeneic T cells in a murine DTH model. Our data demonstrate that peptides derived from highly conserved regions of the class II MHC alpha chain can alter T-lymphocyte immune responses both in vitro and in vivo. These results have important implications for the development of a novel therapy for immune mediated diseases.
Single-Step Synthesis of Silver-Doped Titanium Dioxide: Influence of Silver on Structural, Textural, and Photocatalytic Properties (2014)

The silver-doped titanium dioxide (Ag–TiO2) photocatalysts with varied silver content ranging from 0.75 at % to 3.5 at % were synthesized by a single-step sol–gel method. The role of silver content on the properties of photocatalyst has been studied. The doping of 0.75 at % silver in TiO2 produced thermally stable TiO2 anatase phase with smallest particle size, uniform particles size and morphology, high surface area and low-energy excitation characteristics. The Ag–TiO2 sample with 0.75 at % silver possesses predominantly finely dispersed silver species (Ag2O and AgO) on the surface. The proportion of surface agglomerated silver metal (Ag0) increases as the silver content in the Ag–TiO2 sample increases. The silver oxide species were observed to be responsible for better physicochemical and catalytic properties. The TiO2 with 0.75 at % silver was found to be an efficient photocatalyst showing enhanced photocatalytic activity for aqueous medium photocatalytic degradation of phthalic acid in the presence of UV radiation and air.
Invariance of Doppler bandwidth with flow axis displacement (2002)

It is known that if single-frequency, continuous-wave ultrasound or electromagnetic energy is reflected from straight line flow, defined here as one or more scatterers moving with constant velocity along an infinite straight line, the Doppler effect will shift the echo spectrum center frequency from the transmitted value, and broaden its bandwidth. It is shown here that if such straight line flow is shifted anywhere in the field without change of orientation, the absolute echo bandwidth remains unchanged. This result is unexpected, since the bandwidth arises from amplitude modulation of the echo from the scatterers as they pass through the incident field, and the shape of this field varies with position. The Doppler bandwidth may therefore be used to estimate the transverse component of the flow velocity anywhere in the sound beam. The effect of the system relative aperture on the minimum spectral broadening and maximum frequency indication may also be assessed at any range.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Robust and accelerated Bayesian inversion of marine controlled-source electromagnetic data using parallel tempering (2013)

ABSTRACT Bayesian methods can quantify the model uncertainty that is inherent in inversion of highly nonlinear geophysical problems. In this approach, a model likelihood function based on knowledge of the data noise statistics is used to sample the posterior model distribution, which conveys information on the resolvability of the model parameters. Because these distributions are multidimensional and nonlinear, we used Markov chain Monte Carlo methods for highly efficient sampling. Because a single Markov chain can become stuck in a local probability mode, we run various randomized Markov chains independently. To some extent, this problem can be mitigated by running independent Markov chains, but unless a very large number of chains are run, biased results may be obtained. We got around these limitations by running parallel, interacting Markov chains with “annealed” or “tempered” likelihoods, which enable the whole system of chains to effectively escape local probability maxima. We tested this approach using a transdimensional algorithm, where the number of model parameters as well as the parameters themselves were treated as unknowns during the inversion. This gave us a measure of uncertainty that was independent of any particular parameterization. We then subset the ensemble of inversion models to either reduce uncertainty based on a priori constraints or to examine the probability of various geologic scenarios. We demonstrated our algorithms’ fast convergence to the posterior model distribution with a synthetic 1D marine controlled-source electromagnetic data example. The speed up gained from this new approach will facilitate the practical implementation of future 2D and 3D Bayesian inversions, where the cost of each forward evaluation is significantly more expensive than for the 1D case.
Brochocin-C, a new bacteriocin produced by Brochothrix campestris (1993)

Brochotrix campestris ATCC 43754 produces a bacteriocin inhibitory towards Brochothrix thermosphacta, lactobacilli, Listeria spp., and other gram-positive bacteria. This antimicrobial agent is heat stable, sensitive to proteases, catalase insensitive, and free of organic acids. No phage particles were detected by transmission electron microscopy. Muramidase activity was not detected in the preparations. On the basis of established criteria, the antimicrobial agent was classified as a bacteriocin and named brochocin-C.
Growth of Group III Nitrides. A Review of Precursors and Techniques (1996)

The AlGaInN quaternary alloy system is uniquely suited for numerous device applications because the bandgap can be varied from 1.9 to 6.2 eV by changing the alloy composition. Growth of epitaxial device-quality group III (Al, Ga, In) nitride films has been hindered by a lack of suitably lattice matched substrates, the large equilibrium dissociation pressure of N2 from the nitrides at typical growth temperatures, and predeposition reactions in the commonly employed metal−organic chemical vapor (MOCVD) precursors. The most successful films have been grown at temperatures in excess of 900 °C by MOCVD. However, high growth temperatures may limit compatibility and incorporation of group III nitrides with existing fabrication technologies and devices. Attempts to lower deposition temperature include activated nitrogen sources and alternative precursors. This review will discuss improvement in film properties as a function of growth chemistry and will focus on MOCVD precursors used specifically for the growth of group III nitrides.
Regulation of the p53 Tumour Suppressor Stability and Activity (2002)

The p53 tumour suppressor protein plays a crutial role in regulating cell growth and death in response to various types of cellular stress. The loss of its function is the most common event leading to the development of cancer. normal cells, p53 is present at low levels because the protein is rapidly degraded by the ubiquitin-mediated proteasome pathway following synthesis. Stress induced signals inhibit p53 degradation, leading to rapid stabilization and accumulation of p53 protein in the cell, and followed by p53 protein activation by mechanisms including phosphorylation and acetylation. The complexity of the pathways regulating p53 stabilization and activation, as well as possible p53 activation in response to small chemical compounds used in certain experimental anti-cancer therapy approaches, are discussed in this review.
Linear bases for representation of natural and artificial illuminants (1997)

By the principal-value decomposition process, we have obtained two linear bases for representing the spectral power distributions of illuminants, applicable for algorithms of color synthesis and analysis in artificial vision: one from experimental measurements of daylight and another combining both natural and artificial illuminants. The first basis adequately represents daylight with dimension 3, in accordance with the previous results of Judd [J. Opt. Soc. Am.54, 1031 (1964)]; however, it does not adequately represent artificial illuminants, even with a higher dimension. In the case of the second basis, many good results are obtained in the reconstruction of the spectral power distribution both of daylight and of artificial illuminants, including some fluorescent lights, with dimension 7 or even less. In consequence, we show the possibility of obtaining linear bases of a low dimension, even when the set of illuminants that we try to represent presents a certain variability in shape.
Low loss GaN waveguides at the visible spectral wavelengths for integrated photonics applications (2017)

We perform comprehensive studies on the fundamental loss mechanisms in III-nitride waveguides in the visible spectral region. Theoretical analysis shows that free carrier loss dominates for GaN under low photon power injection. When optical power increases, the two photon absorption loss becomes important and eventually dominates when photon energy above half-bandgap of GaN. When the dimensions of the waveguides reduce, the sidewall scattering loss will start to dominate. To verify the theoretical results, a high performance GaN-on-sapphire waveguide was fabricated and characterized. Experimental results are consistent with the theoretical findings, showing that under high power injection the optical loss changed significantly for GaN waveguides. A low optical loss ~2 dB/cm was achieved on the GaN waveguide, which is the lowest value ever reported for the visible spectral range. The results and fabrication processes developed in this work pave the way for the development of III-nitride integrated photonics in the visible and potentially ultraviolet spectral range for nonlinear optics and quantum photonics applications.