gebhart/patrepeval huggingface dataset:
On analog signature analysis (1999)

Article On analog signature analysis Share on Authors: Franc Novak Jožef Stefan Institute, Slovenia Jožef Stefan Institute, SloveniaView Profile , Bojan Hvala Department of Mathematics, University of Maribor, Slovenia Department of Mathematics, University of Maribor, SloveniaView Profile , Sandi Klavžar Department of Mathematics, University of Maribor, Slovenia Department of Mathematics, University of Maribor, SloveniaView Profile Authors Info & Claims DATE '99: Proceedings of the conference on Design, automation and test in EuropeJanuary 1999 Pages 52–eshttps://doi.org/10.1145/307418.307499Published:01 January 1999 1citation113DownloadsMetricsTotal Citations1Total Downloads113Last 12 Months0Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
A Sodium Ion Based Organic Radical Battery (2010)

A sodium ion based organic radical battery has been developed using a polynorbornene derivative radical polymer as the cathode active material. The electrochemical performances of the battery are preliminarily investigated, showing the cyclability of the battery. The battery delivers a discharge capacity of at the 1st cycle and a capacity retention of at the 50th cycle.
Electroactive Polymer Fiber Separators for Stable and Reversible Overcharge Protection in Rechargeable Lithium Batteries (2014)

An approach was developed to fabricate functionalized separators capable of providing long-term overcharge protection for secondary lithium batteries. Free-standing non-woven fiber membranes consisting of an electroactive polymer and a supporting polymer were prepared by an inexpensive and scalable electrospinning technique. The membranes sustained large shunt current densities despite the presence of an inert polymer component that dilutes the electroactive polymer. A bilayer fiber separator prepared by this method provided a reversible voltage-regulated current shunt for a Li1.05Mn1.95O4/Li cell for more than 1000 135% overcharge cycles at a 2/3 C rate, which is the most stable overcharge protection yet reported. This approach enables better distribution of the electroactive polymer which should reduce the cost of overcharge protection separators.
Genetic Diversity of Hepatitis B Virus Strains Derived Worldwide: Genotypes, Subgenotypes, and HB<sub>s</sub>Ag Subtypes (2004)

Sequences of 234 complete genomes and 631 hepatitis B surface antigen genes were used to assess the worldwide diversity of hepatitis B virus (HBV). Apart from the described two subgenotypes each for A and F, also B, C, and D divided into four subgenotypes each in the analysis of complete genomes supported by significant bootstrap values. The subgenotypes of B and C differed in their geographical distribution, with B1 dominating in Japan, B2 in China and Vietnam, B3 confined to Indonesia, and B4 confined to Vietnam, all strains specifying subtype ayw1. Subgenotype C1 was common in Japan, Korea, and China; C2 in China, South-East Asia, and Bangladesh, and C3 in the Oceania comprising strains specifying adrq-, and C4 specifying ayw3 is encountered in Aborigines from Australia. This pattern of defined geographical distribution was less evident for D1-D4, where the subgenotypes were widely spread in Europe, Africa, and Asia, possibly due to their divergence having occurred a longer time ago than for genotypes B and C, with D4 being the first split and still the dominating subgenotype of D in the Oceania. The genetic diversity of HBV and the geographical distribution of its subgenotypes provide a tool to reconstruct the evolutionary history of HBV and may help to complement genetic data in the understanding of the evolution and past migrations of man.
Functional expression and apical localization of the cystic fibrosis transmembrane conductance regulator in MDCK I cells (1997)

The gene product affected in cystic fibrosis, the cystic fibrosis transmembrane conductance regulator (CFTR), is a chlorideselective ion channel that is regulated by cAMP-dependent protein kinase-mediated phosphorylation, ATP binding and ATP hydrolysis. Mutations in the CFTR gene may result in cystic fibrosis characterized by severe pathology (e.g. recurrent pulmonary infection, male infertility and pancreatic insufficiency) involving organs expressing the CFTR. Interestingly, in the kidney, where expression of the CFTR has been reported, impaired ion transport in patients suffering from cystic fibrosis could not be observed. To understand the role of the CFTR in chloride transport in the kidney, we attempted to identify an epithelial cell line that can serve as a model. We demonstrate that the CFTR is expressed constitutively in Madine-Darby canine kidney (MDCK) type I cells, which are thought to have originated from the distal tubule of the dog nephron. We show expression at the mRNA level, using reverse transcriptase-PCR, and at the protein level, using Western blot analysis with three different monoclonal antibodies. Iodide efflux measurements indicate that CFTR expression confers a plasma membrane anion conductance that is responsive to stimulation by cAMP. The cAMP-stimulated iodide release is sensitive to glybenclamide, diphenylamine carboxylic acid and 5-nitro-2-(3-phenylpropylamino)benzoic acid, but not to 4,4'-di-isothiocyanostilbene-2,2'-disulphonic acid, an inhibitor profile characteristic of the CFTR chloride channel. Finally, the polarized localization of the CFTR to the apical plasma membrane was established by iodide efflux measurements and cell-surface biotinylation on MDCK I monolayers. Interestingly, MDCK type II cells, which are thought to have originated from the proximal tubule of the kidney, lack CFTR protein expression and cAMP-stimulated chloride conductance. In conclusion, we propose that MDCK type I and II cells can serve as convenient model systems to study the physiological role and differential expression of CFTR in the distal and proximal tubule respectively.
Distinctive Gene Expression Profiles by cDNA Microarrays in Endometrioid and Serous Carcinomas of the Endometrium (2004)

Endometrial carcinomas are classified by their morphology into two major subtypes. Endometrioid carcinomas (type I) are generally estrogen dependent, well-differentiated, superficially invasive, and have a good outcome. Serous carcinomas (type II) are hormone independent, frequently deeply invasive and widely metastatic, and have a poor prognosis. Microarray technology and analysis allows us to determine if the global gene expression profiles of these two subtypes correlate with their morphologic phenotype. Fresh tissue from 18 endometrial carcinomas was studied: 7 well-, 2 moderately, and one poorly differentiated endometrioid, 4 serous carcinomas, and 4 high-grade mixed endometrioid-serous carcinomas. Labeled cDNA probes were synthesized (Cy5 for tumor, Cy3 for reference) and applied to microarrays containing 18,098 cDNA clones or ESTs. A pool of equal amounts of total RNA from each tumor served as the reference RNA. By unsupervised cluster analysis, the endometrioid carcinomas clustered together and were separate from the serous carcinomas. The high-grade mixed carcinomas clustered with the serous carcinomas. Using a statistical algorithm based on gene expression pattern and conducting a supervised analysis of the two defined groups, we have identified 315 genes that statistically differentiate type I from type II endometrial carcinomas. In addition to corroborating the predicted overexpression of known markers (e.g., ras and catenin in endometrioid carcinomas), the cDNA microarray technique has revealed novel alterations in gene expression relevant to cell cycle, cell adhesion, signal transduction, apoptosis, and tumor progression not previously implicated in endometrial carcinomas. For serous carcinomas, these include aldolase, desmoplakin, integrin-linked kinase, PKC, and metallopeptidase. In conclusion, the gene expression profiles of type I and type II endometrial carcinomas are different. Refinement of these profiles will permit more accurate diagnostic tumor classification and the development of prognosis assays.
Effects of a Novel Disulfide Bond and Engineered Electrostatic Interactions on the Thermostability of Azurin (2004)

Identification and evaluation of factors important for thermostability in proteins is a growing research field with many industrial applications. This study investigates the effects of introducing a novel disulfide bond and engineered electrostatic interactions with respect to the thermostability of holo azurin from Pseudomonas aeruginosa. Four mutants were selected on the basis of rational design and novel temperature-dependent atomic displacement factors from crystal data collected at elevated temperatures. The atomic displacement parameters describe the molecular movement at higher temperatures. The thermostability was evaluated by optical spectroscopy as well as by differential scanning calorimetry. Although azurin has a high inherent stability, the introduction of a novel disulfide bond connecting a flexible loop with small alpha-helix (D62C/K74C copper-containing mutant), increased the T(m) by 3.7 degrees C compared with the holo protein. Furthermore, three mutants were designed to introduce electrostatic interactions, K24R, D23E/K128R, and D23E/K128R/K24R. Mutant K24R stabilizes loops between two separate beta-strands and D23E/K128R was selected to stabilize the C-terminus of azurin. Furthermore, D23E/K128R/K24R was selected to reflect the combination of the electrostatic interactions in D23E/K128R and K24R. The mutants involving electrostatic interactions had a minor effect on the thermostability. The crystal structures of the copper-containing mutants D62C/K74C and K24R have been determined to 1.5 and 1.8 A resolution. In addition the crystal structure of the zinc-loaded mutant D62C/K74C has also been completed to 1.8 A resolution. These structures support the selected design and provide valuable information for evaluating effects of the modifications on the thermostability of holo azurin.
Measures for Making DNS More Resilient against Forged Answers (2009)

The current Internet climate poses serious threats to the Domain Name
System. In the interim period before the DNS protocol can be secured
more fully, measures can already be taken to harden the DNS to make
'spoofing' a recursing nameserver many orders of magnitude
harder. Even a cryptographically secured DNS benefits from having the
ability to discard bogus responses quickly, as this potentially saves
large amounts of computation. By describing certain behaviour that
has previously not been standardised, this document sets out how to
make the DNS more resilient against accepting incorrect responses.
This document updates RFC 2181.
Lipid rafts in health and disease (2007)

Lipid rafts are sphingolipid- and cholesterol-rich domains of the plasma membrane which contain a variety of signalling and transport proteins. Different subtypes of lipid rafts can be distinguished according to their protein and lipid composition. Caveolae are types of rafts that are rich in proteins of the caveolin family (caveolin-1, -2 and -3) which present a distinct signalling platform. The importance of lipid raft signalling in the pathogenesis of a variety of conditions, such as Alzheimer's, Parkinson's, cardiovascular and prion diseases, systemic lupus erythematosus and HIV, has been elucidated over recent years and makes these specific membrane domains an interesting target for pharmacological approaches in the cure and prevention of these diseases. This Review analyses the importance of lipid raft proteins and lipids in health and disease, with a focus on the current state of knowledge.
Tumor necrosis factor alpha has a crucial role in increased reactive oxygen species production in platelets of mice injected with lipopolysaccharide (2019)

Increased reactive oxygen species (ROS) production leads to tissue damage observed in sepsis and lipopolysaccharide (LPS)-exposed animals. LPS stimulates cytokines releasing, including tumor necrosis factor alpha (TNF-α), that is important to ROS production. Platelets, considered inflammatory cells, generate ROS when exposed to LPS <i>in vivo</i>, but not when they are incubated <i>in vitro</i> with this compound. Therefore, we investigated the role of TNF-α on the increased intraplatelet ROS levels after LPS treatment. Mice were injected with LPS (1 mg/kg) or TNF-α (10 ng/kg), and blood was collected to prepare the washed platelets. Animals were treated with infliximab (anti-TNF-α antibody), R-7050 (non-selective TNF-α receptor antagonist) or apocynin (NADPH oxidase inhibitor). At 48 h after LPS or TNF-α injection, the ROS levels in ADP (25 µM)-activated platelets were evaluated by flow cytometry. Our data showed that injection of mice with LPS increased by 4-fold the ROS production (p < 0.05), which was significantly reduced by the treatments with infliximab, R-7050 or apocynin. Injection of mice with TNF-α markedly elevated the ROS formation in platelets (p < 0.05) that was reduced by infliximab, R-7050 or apocynin treatments. In separate experiments, platelets from saline-injected mice were incubated with TNF-α (30 to 3000 pg/mL) in absence or presence of infliximab, R-7050, apocynin or GKT137831 (NOX1/NOX4 inhibitor) before ROS measurements. TNF-α <i>in vitro</i> markedly increased the ROS levels, an effect significantly reduced by all treatments. Therefore, platelets are involved in the oxidative stress induced by LPS through TNF-α action, and NADPH oxidase takes part in this effect.
Le Déméter 2021 (2021)

La pandémie de Covid-19 a produit un choc d’une ampleur sans précédent. Dans un tel contexte d’incertitudes, les champs de priorités se resserrent sur l’essentiel. L’alimentation, comme la santé, fait partie de ces enjeux universels et atemporels, au cœur des sécurités collective et individuelle et reste le fondement de notre quotidien. Cette nécessité vitale est conditionnée par une activité agricole, elle-même bouleversée, partout sur la planète, par l’accélération des changements géopolitiques, économiques, environnementaux, sociétaux et technologiques. À partir de l’analyse d’une série de grandes ruptures et d’enjeux stratégiques, cette 27e édition du Déméter questionne les trajectoires du développement agricole et les conditions de la sécurité alimentaire dans un monde où la résilience, l’adaptation, l’innovation et la coopération demeurent plus que jamais déterminantes pour relever des défis inédits.
Untersuchungen zur Langkettenverzweigung in Polyäthylenen (1970)

Abstract Polyäthylene verschiedener Dichten, Schmelzindizes (MFI) und Polymerisationsarten wurden auf Langkettenverzweigung (LKV) hin untersucht. Dazu wurden die Molgewichte M w und Grenzviskositäten von Fraktionen mit Viskositäten zwischen 0,2 und 3,2 (Hochdruck‐PE) bzw. 0,2 und 10 (Niederdruck‐PE) gemessen. Die Verminderung der Grenzviskosität eines verzweigten (Hochdruck‐)Polyäthylens gegenüber einem linearen (Niederdruck‐)Polyäthylen gleichen Molgewichtes wurde als Maß für die LKV benutzt. Bei Hochdruckpolyäthylenen nimmt die LKV mit fallender Dichte zu. Im mittleren Molgewichtsbereich ist die Differenzierung am stärksten. Durch Variation der Polymerisationsbedingungen läßt sich die LKV bei konstanter Dichte beeinflussen. An Niederdruckpolymerisaten konnte keine LKV festgestellt werden. Sie unterscheiden sich dadurch also deutlich von Hochdruckpolyäthylene gleicher Dichte. Niederdruckpolymerisate enthalten also allenfalls Kurzkettenverzweigungen, die vor allem durch Copolymerisation erzeugt werden können. Es wurden verschiedene theoretische Ansätze auf ihre Verwendbarkeit für quantitative Aussagen über n, die Zahl der LKV pro Molekül, geprüft. Mit dem Ansatz [η]v/[η] 1 = g 1,3 (n = f(g)) äßt sich formal der Verlauf unserer Meßkurven am besten beschreiben, wenn gleichzeitig angenommen wird, daß der Abstand zwischen den Verzweigungspunkten bei den Fraktionen einer Probe weitgehend unabhängig vom Molgewicht ist (n/M = const.). Bei Darstellung der Molgewichtsverteilungen von Hochdruck‐PE unter Berücksichtigung ihrer LKV ergibt sich wie beim Niederdruck‐PE in vielen Fällen eine logarithmische Normalverteilung. Als Beispiel für anwendungstechnische Konsequenzen aus der LKV werden Meßergebnisse angeführt, die eine Verbesserung der Fließfähigkeit einer PE‐Schmelze mit zunehmender LKV erkennen lassen.
Development-Length Requirements for Fully Developed Laminar Pipe Flow of Inelastic Non-Newtonian Liquids (2007)

In the current study, we report the results of a detailed and systematic numerical investigation of developing pipe flow of inelastic non-Newtonian fluids obeying the power-law model. We are able to demonstrate that a judicious choice of the Reynolds number allows the development length at high Reynolds number to collapse onto a single curve (i.e., independent of the power-law index n). Moreover, at low Reynolds numbers, we show that the development length is, in contrast to existing results in the literature, a function of power-law index. Using a simple modification to the recently proposed correlation for Newtonian fluid flows (Durst, F. et al., 2005, “The Development Lengths of Laminar Pipe and Channel Flows,” J. Fluids Eng., 127, pp. 1154–1160) to account for this low Re behavior, we propose a unified correlation for XD∕D, which is valid in the range 0.4<n<1.5 and 0<Re<1000.
ELECTRON EMISSION FROM CARBON NANOTUBES (2007)

Carbon nanotubes, nanometer-diameter tubes made of carbon atoms, have garnered significant attention from researchers over the past 15 years due to their outstanding properties such as excellent electronic transport characteristics and mechanical strength. Because of their ability to carry extremely high current densities, their high aspect ratio, and small tip radius that enhances an external electric field greatly, one particularly promising area of interest has been the usage of nanotubes as electron sources. In this article we will try to provide an overview of the subject from various experimental and theoretical angles.
Copper plating the ground test accelerator RFQ (2002)

The copper-plating process for the ground test accelerator (GTA) radio frequency quadrupole (RFQ) vanes required a full development program and tight quality control procedures. The authors discuss the GTA RFQ copper-plating critical issues; the plating-fixture development; the copper-plating processes; RFQ plating specifications as they apply to thickness, uniformity and adhesion; and the quality assurance procedures. The copper plating development program utilized full-size RFQ major and minor vane mockups to develop plating fixturing and to establish the plating parameters necessary to meet the GTA RFQ plating specifications. After several modifications to the fixturing and plating processes, the mockup vanes were copper plated to GTA specifications and the actual GTA RFQ could then be copper plated. This development technique, using full-size mockups for establishing reliable and accurate plating fixtures and processes, is the key to success for copper-plating.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Geomagnetic control of diffusion in the upper atmosphere (1964)

Physical mechanisms governing atmospheric diffusion and existence of geomagnetic anomaly in ionosphere
BUILDING CARS WITH MACHINES THAT SEE (1985)

This article discusses how the automobile manufacturers are using machine vision as a technique to improve the quality of their cars and the efficiency of their plants. Before machine vision was developed, robots were dependent on skilled human workers to make the necessary correction when a car came down the conveyor slightly skewed in its cradle. Now with machine vision robots and other sophisticated industrial machines have the ability to see what they are doing and to adapt to the vagaries of a world where things don't always show up exactly where they should be. The author of this article observed firsthand the following application: welding body seams of varying widths; tightening imprecisely located bolts; laser-marking identification numbers on engines and transmissions; arranging car hoods on racks that have unevenly spaced slots; and gauging precise body dimensions using lasers and video cameras.
A Sense of Belonging of Teachers of Catholic Schools for Secondary Ed Ucation (1999)

A sense of belonging is conceptualized with the help of some theoretical notions of J. Searle. According to Searle institutional facts are created by constitutive rules. Through these rules people coordinate their actions within institutions. Institutional facts need collective acceptance or agreement. Activities of Catholic schools by which they express their identity, can be seen as institutional facts. These facts can vary from religious meetings (school mass) to study meetings on school identity by teachers. Teachers differ in the type of involvement with these collective actions. This empirical study shows that the difference in involvement in activities that are an expression of the collective identity of the school, is related to the religious profile of teachers. This interaction between personal and collective identity gives insight into the dynamics of the construction of identity of religiously affiliated schools.
Saccharide–RNA recognition (1998)

Among saccharides, the antibiotics of the aminoglycoside family are the best-studied class of molecules interacting with RNA. By binding to RNA targets, aminoglycosides act as inhibitors of protein biosynthesis, they interfere with protein-RNA interaction of retroviral regulatory elements, and they inhibit the catalytic action of ribozymes. Here, we survey the available data on molecular structural details of aminoglycoside-RNA interaction.
Recent developments in opening photoconductive semiconductor switches (1987)

While developing high power photoconductive semiconductor switches (PCSS) for opening and closing (toggling) applications, we have recorded extremely fast opening times and what appears to be the onset of non-destructive electron avalanching. Using 1- and 2-inch diameter wafers of GaAs, Cr:GaAs, and Au:Si, we have switched a 50-ohm, 80-ns transmission line at voltages up to 65 kV. In the dark, the GaAs switches will stand-off dc fields up to 30 kV/cm in SF/sub 6/. Upon optical triggering, the behavior depends on the average electric field. Below 4 kV/cm (8 kV/cm doped) they open with a 20-ns (< 3 ns doped) exponential recovery time. When the light is removed above these fields, the switches lock on, conducting whatever current the circuit will supply and stabilizing to 4 kV/cm (8 kV/cm doped) across the switch. Additionally, reliable triggering of a 2-inch GaAs switch (3.4-cm gap) in this ''locking on'' mode was achieved with a 70-..mu..J, 532-nm, 10-ns light pulse (less than 1/100th the light required to trigger the switch at low voltages). The Au:Si samples did not lock-on. They opened with an exponential recovery time of 20 to 40 ns at fields up to 35 kV/cm. Undoped silicon samples show recovery timesmore » of several hundred microseconds.« less