gebhart/patrepeval huggingface dataset:
Multi-pitch detection algorithm using constrained Gaussian mixture model and information criterion for simultaneous speech (2004)

In this paper, a co-channel multi-pitch detection algorithm is described. We suggest the importance of this when prosodic information is need to be extracted separately from respective F 0 patterns of concurrent utterances. Though temporal continuity of speech prosody should be considered, we discuss a process done independently on each single frame as the first step. A model of multiple harmonic structures is constructed with a mixture of tied Gaussian mixtures with which a single harmonic structure is modeled. Our algorithm enables to detect both a number of concurrent speakers, and each spectral envelope of underlying harmonic structure based on a maximum likelihood estimation of the model parameters using EM algorithm and an information criterion. It operates without a priori information of F 0 contours and a restriction of a number of speakers, and it also extracts accurate F 0 s as continuous values with simple procedures in spectral domain. Experiments showed our algorithm outperformed well-known cepstrum for both speech signals of a single speaker and simultaneous two speakers.
Intracellular viral localization in murine coxsackievirus-B3 myocarditis. Ultrastructural study by electron microscopic in situ hybridization. (1997)

Group B Coxsackieviruses are a common cause of myocarditis. To detect the viral genome and its localization in the myocardium, we examined C3H/He mice with Coxsackievirus B3 (CVB3) myocarditis on days 5, 8, and 14 after inoculation by the reverse transcriptase polymerase chain reaction and by in situ hybridization. Sense and antisense CVB3 RNA were detected in the myocardium of all mice up to day 14 by reverse transcriptase polymerase chain reaction. Light microscopic in situ hybridization with a cDNA probe for CVB3 showed clusters of positive signals in the areas of myocardial necrosis and cell infiltration. With electron microscopic in situ hybridization, CVB3 RNA was detected in the cytoplasm of cardiocytes, between the myofibrils, near the mitochondria, and in tubular or vesicular structures. Viral RNA was also detected in necrotic debris, in the cytoplasm of macrophages, and in the cytoplasm of interstitial fibroblasts. These findings suggest that CVB3 RNA is replicated in the cytoplasm of cardiocytes, transferred into tubular or vesicular structures, released into the interstitium, and phagocytosed by macrophages. Some positive signals were also detected in the cytoplasm of cardiocytes showing close contact with infiltrating lymphocytes, suggesting that the lymphocytes recognized virus-infected cardiocytes and caused cell-mediated immune cardiocyte damage.
Fecal Calprotectin and Lactoferrin as Noninvasive Markers of Pediatric Inflammatory Bowel Disease (2009)

FC and FL are both significantly elevated in children with IBD, and the interaction of these 2 biomarkers may produce a better initial diagnostic test compared with their use in isolation.
Surface‐Functionalized Polymer Nanoparticles for Selective Sequestering of Heavy Metals (2006)

Xanthate-mediated (reversible addition-fragmentation chain transfer) emulsion polymerization has been used to create novel polystyrene nanoparticles with functionalized surfaces (see Figure) for the selective sequestering of heavy metals from water below ppm levels. These nanoparticles show a high degree of selectivity for HgII over CoII. This technology has potential for the selective remediation of heavy metals from the human blood system. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2006/c1712_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Lymphocyte‐specific protein 1: a specific marker of human leucocytes (1999)

While both murine and human homologues of the LSP1 gene (lymphocyte-specific gene 1) and its protein products have been identified, studies on human LSP1 have been limited. The present report describes a detailed immunocytochemical study of the distribution and localization of human LSP1 in both normal and neoplastic cells and tissues. The specificity of the monoclonal anti-LSP1 reagent was confirmed by expression cloning and transfection studies. The intracellular 60 000 MW LSP1 protein was found to be present in peripheral blood B cells, monocytes and granulocytes but absent in a subpopulation of circulating T cells (10-15% of CD3-positive T cells). The presence of LSP1 protein in medullary thymocytes, but only in scattered cortical thymocytes, provided additional evidence for heterogeneity of expression in T cells. Novel observations also included the presence of LSP1 in plasma cells, dendritic cells and Langerhans' cells. The leucocyte-restricted distribution of LSP1 protein means that it may play an important role in haematopathology. LSP1 protein was detected in a wide range of leukaemias and lymphomas, particularly of B-cell origin, and in tumour cells in classical Hodgkin's disease. Of interest was the indication of a reciprocal relationship in the expression of LSP1 and ALK (anaplastic lymphoma kinase) proteins in patients with anaplastic large cell lymphoma. As the anti-LSP1 reagent used in the present study recognizes a formalin-resistant epitope it should be of considerable value in the diagnosis of routinely fixed material.
EFFECTS OF ULTRASONIC WAVES ON THE REFRACTIVE MEDIA OF THE EYE (1952)

A PROGRAM of experimental research has been undertaken in cooperation with the Department of Physics at the Catholic University of America to study the production and possible clearing of opacities in the refractive media of the eye by means of ultrasonic irradiation. Although up to the present it has not been possible to clear such opacities, significant findings have been obtained in the study of the effects of intense ultrasonic waves in excised calves' eyes. It is the purpose of this paper to report this work at its present stage of development. The term ultrasonics designates sound waves having a frequency beyond the audible range, i. e., above 30,000 cps. Although ultrasonic waves differ from ordinary audible sound only by having a higher frequency and smaller wave length, these properties greatly influence their propagation through matter. Much information about the behavior of different media has been obtained using ultrasonic waves
Expression of CD44 splicing isoforms in lung cancers: dominant expression of CD44v8-10 in non-small cell lung carcinomas. (1998)

We examined CD44 isoform expression in 138 frozen tissue samples, which included primary lung carcinomas, adjacent non-tumorous lung tissues and benign lung diseases, by both reverse transcriptase polymerase chain reaction (RT-PCR) and immunohistochemical analyses. CD44v8-10 mRNA and protein were dominantly expressed in non-small cell lung carcinomas (NSCLC), while non-tumorous tissues principally expressed CD44s and small cell lung carcinomas (SCLC) expressed either CD44s or no detectable CD44. These results indicate that CD44v8-10 is the dominant splicing isoform in NSCLC and can be practically utilized as a diagnostic marker and therapeutical target in NSCLC.
A Novel QoE-Aware Multicast Mechanism for Video Communications over IEEE 802.11 WLANs (2012)

During the past few years, the development of video services over wireless networks has been driven by Quality of Service (QoS) parameters and service level agreements. Even though QoS parameters, such as packet losses, jitter and delays are good indicators of the service provided by the underlying network services to the applications, they fall short on providing a better measure of the Quality of Experience (QoE) to the end-user. In order to gain a better understanding of the benefits in terms of the QoE guarantees, it is essential to evaluate the effectiveness of the enabling protocol mechanisms. In this paper, we introduce a novel multicast service for the IEEE 802.11 WLAN standard. The proposed service combines a novel MAC scheme and layered video, guaranteeing a minimum acceptable video quality to all the members of the multicast group through the base layer. To avoid penalizing the users capable of receiving data at higher rates and the performance of an IEEE 802.11 WLAN, the enhancement layers are transmitted using a higher transmission rate. We show that by properly coupling the video and multicast control mechanisms, the QoS as well as the QoE requirements of the end-user can be guaranteed. The performance of the proposed system architecture is extensively investigated by simulations and through numerical evaluation of relevant QoS and QoE metrics. Furthermore, our results show that the real-time video streaming quality of the total system can be greatly improved while keeping downward compatibility with the IEEE 802.11 multicast mechanism.
Adaptive Broadcasting for Similarity Queries in Wireless Content Delivery Systems (2008)

We present a new adaptive and energy-efficient broadcast model to support flexible responses to client queries. Clients do not have to request documents by name, since they may know the characteristics of the documents but not the document names or IDs. In our model, clients specify requirements through attributes, and servers broadcast documents that match client requests at a prespecified level of similarity. A given document may satisfy several clients, so the server broadcasts a minimal set of documents that achieves a desired level of satisfaction in the client population. The server obtains randomized feedback from clients and adapts its broadcast program accordingly. Clients use a selective tune-in scheme based on approximate indexing to conserve energy. Our model captures client interest patterns efficiently and accurately and scales very well with the number of clients while reducing the overall client average waiting times. The selective tune-in scheme reduces client energy consumption greatly, with a modest wait time increase.
A broadband switching system for public network (2005)

Research and development of broadband switching systems for public networks is described. For early introduction of broadband ISDN in the public network, all of the necessary network elements, eg. terminal equipment, subscriber loop equipment; switching system, etc are being developed. From the viewpoint of services, broadband is necessary for interactive image application. Broadband network services can be mapped into call switching, distribution, virtual network and private line. For subscriber loop network double star configuration, distribution loop and feeder loop is adopted. The UNI is 622Mb/s including combination of ATM channels and STM channels. The switching system is composed of the Host Switch and Broadband Remote Switching Unit (BRSU), to provide both ATM and STM switching. CATV service is provided by an STM distribution switch in the BRSU. Signaling protocol for UNI is based on DSSI for N-ISDN. The signaling between BRSU and the Host is based on ISUP of CCS7. Customer premises network is based on DQDB or passive bus method. The protoope system developed in 1989 provided video telephony, CATV, CBR and N-ISDN services.
[Validation of TKT medium for detection of Streptococcus agalactiae in bulk milk samples]. (1997)

A selective medium for quantitative determination of Streptococcus agalactiae in bulk milk samples was tested. Among the medium bases, Edwards medium (EW) supplemented with 6 to 9% (v/v) of carefully washed sheep erythrocytes was proved to be best (Tab. V). The production of sphingomyelinasis C (BHE, Tab. II) or D (COREX, Tab. I) as a supplement supporting the formation of specific hemolytic zones in the medium, was tested in four strains of Staphylococcus aureus and seven strains of Corynebacterium pseudotuberculosis. Submersion aerated cultivation was used for enzyme production; optimum cultivation time is about 100 hours (Figs. 1, 2). To determine the activity of the enzymes produced a screening method was developed applying hemolytic interactions with CAMP factor of Str. agalactiae. Method sensitivity and reproducibility are sufficiently high for the purposes of observation (Tab. III). The produced enzymes did not show any changes in their activity over the whole period of storage under all conditions of storage (32 days/7 degrees C, 48 weeks/-18 degrees C, lyophilizate 48 weeks/20 degrees C). Sphingomyelinasis C is more resistant to heat denaturation, not losing its activity even after being warmed to 85 degrees C for 5 min; sphingomyelinasis D is sensitive to temperatures higher than 50 degrees C (Fig. 3). COREX was selected (sphingomyelinasis D), produced by the strain CNTCC 18/62 of C. pseudotuberculosis. The enzyme was applied either in raw filtrate of the medium (sterilization by repeated membrane filtration) or in prepurified form obtained by cold acetone precipitation, providing the same results. The medium is highly specific and likely enough selective for Str. agalactiae, unlike BHE it does not provide any positive results with UBERIS-factor+strains of Str. uberis (Tab. V). Optimum cultivation time is 18 hours; prolongation of cultivation for more than 24 hours brings about the risk of falsely positive readings (Tab. VI) in the strains of accompanying microflora (Morganella morganii ssp. morganii, delta-hemolytic staphylococci).
Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect (1999)

We performed a prospective, randomised double-blind study in 24 patients undergoing high tibial osteotomy to evaluate the effectiveness of human recombinant osteogenic protein (OP-1) on a collagen type-I carrier in a critically-sized fibular defect. The study had two phases, each evaluated by clinical, radiological and DEXA methods during the first postoperative year. The first concerned the validation of the model of the fibular defect, using positive (demineralised bone) and negative (untreated) controls. The second phase concerned the osteogenic potential of OP-1 on collagen type-I v collagen type-I alone. The results of the first phase established the critically-sized nature of the defect. In the untreated group no bony changes were observed while, in the demineralised bone group, formation of new bone was visible from six weeks onwards. The results of the second phase showed no significant formation of new bone in the presence of collagen alone, while in the OP-1 group, all patients except one showed formation of new bone from six weeks onwards. This proved the osteogenic activity of OP-1 in a validated critically-sized human defect.
Photoluminescence of Tensile Strained, Exactly Strain Compensated, and Compressively Strained<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi>Si</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>−</mml:mo><mml:mi mathvariant="italic">x</mml:mi><mml:mo>−</mml:mo><mml:mi mathvariant="italic">y</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>Ge</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="italic">x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>C</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="italic">y</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math>Layers on Si (1998)

Band edge related photoluminescence is observed from strain compensated ${\mathrm{Si}}_{1\ensuremath{-}x\ensuremath{-}y}{\mathrm{Ge}}_{x}{\mathrm{C}}_{y}$ multiple quantum wells. For $(87\ifmmode\pm\else\textpm\fi{}4)\AA{}$ thick quantum wells, the no-phonon energy decreases linearly with increasing C content as $\ensuremath{-}y(6.8\mathrm{eV})$. The band gap for unstrained ${\mathrm{Si}}_{1\ensuremath{-}y}{\mathrm{C}}_{y}$ material is deduced for carbon concentrations lower than 0.85%. An initial energy increase and a subsequent energy decrease on the way from tensile strained ${\mathrm{Si}}_{1\ensuremath{-}y}{\mathrm{C}}_{y}$ and from compressively strained ${\mathrm{Si}}_{1\ensuremath{-}x}{\mathrm{Ge}}_{x}$ alloys towards exactly strain compensated ${\mathrm{Si}}_{1\ensuremath{-}x\ensuremath{-}y}{\mathrm{Ge}}_{x}{\mathrm{C}}_{y}$ structures is measured. The different band alignments and strain-induced electron and hole level crossing effects are discussed.
Revealing the failure mechanism of transition-metal chalcogenides towards the copper current collector in secondary batteries (2020)

A new failure mechanism of transition-metal chalcogenide electrodes in rechargeable batteries due to corrosion on the Cu current collector.
Proliferation and cytotoxicity of lectin‐induced lymphokine‐activated killer (LILAK) cells (1991)

More than 10(11) killer cells are needed for adoptive immunotherapy, but it is difficult to obtain so many from patients. Peripheral blood lymphocytes (PBL) treated with lectin and then with recombinant interleukin-2 (rIL-2) give many lectin-induced lymphokine-activated killer (LILAK) cells, studied here for proliferation, cytotoxicity, IL-2 receptors (IL-2R) and subsets. PBL obtained from hepatoma patients or healthy adults were incubated with phytohaemagglutinin (PHA) or concanavalin A (ConA) for 3 days and with rIL-2 for 4 days. Then the medium was replaced with fresh medium containing rIL-2 every 3 or 4 days, with the volume increased as cells proliferated. Cytotoxicity was expressed as the percentage lysis of target cells by 4 h 51Cr release. LILAK cells from healthy adults increased 120-fold in 2 weeks when incubated with ConA; the lymphokine-activated killer (LAK) cells increased 7-fold. The percentage of IL-2R+ cells increased more with ConA than with rIL-2 alone. ConA induced more suppressor T cells than PHA. LILAK cells obtained from patients by PHA treatment increased 180-fold in 2 weeks. Their cytotoxicity to Daudi cells was 1% before culture and 91% in 2 weeks; that of LAK cells was 60%. LILAK cells were cytotoxic to the tumour target cells, but not to allogeneic PBL. Adoptive immunotherapy may become more practical if many LILAK cells can be obtained at once by large-scale culture, such as by a hollow-fibre system.
Monoclonal antibodies against Pseudomonas aeruginosa outer membrane antigens: isolation and characterization (1982)

Hybridomas secreting monoclonal antibodies specific for Pseudomonas aeruginosa outer membrane antigens were isolated. One of the antibodies was highly specific for the O antigen of the lipopolysaccharide of International Antigen Typing Scheme serotype 5 strains, reacting only weakly with a serotype 17 strain and failing to react with the outer membranes of strains representing 15 other serotypes. This monoclonal antibody was able to agglutinate heat-killed bacterial cells as well as lipopolysaccharide-coated sheep erythrocytes. Two other monoclonal antibodies were able to interact with the outer membranes of strains representing all 17 serotypes, although they were unable to agglutinate heat-killed bacterial cells. One of these was shown to be specific for the major outer membrane lipoprotein H2. The antigenic site against which this monoclonal antibody reacted was present in the outer membranes of two Pseudomonas fluorescens strains, two Pseudomonas putida strains, a Pseudomonas anguilliseptica strain, and an Azotobacter vinelandii strain, but not in the outer membranes of five other bacterial species.
Xenopus Pax-6 and retinal development (1997)

We have cloned a homolog of Pax-6 in Xenopus laevis. Its deduced amino acid sequence has a 95% overall identity with Pax-6 homologs in other vertebrates. It is expressed early in development in cells fated to form the eye and parts of the forebrain, hindbrain, and spinal cord. It has two phases of expression in the eye. In the early phase, from stage 12.5 to stage 33/34, Xenopus Pax-6 is expressed throughout the developing retina. In the late phase, after stage 33/34, it is excluded from mature cells in the outer half of the retina and from cells in the ciliary marginal zone, remaining only in amacrine and ganglion cells. Misexpression of Pax-6 early in development results in axial defects, but no specific eye phenotype is observed. Targeted misexpression in the retina at later stages does not result in any significant bias toward formation of amacrine or ganglion cells or away from photoreceptors. Ectopic expression of the proneural gene NeuroD alters the pattern of Pax-6, substantially reducing its expression in the eye field and later reducing or eliminating the eye itself. Our results show that Pax-6 expression appears to be necessary, but not sufficient, for eye formation in Xenopus.
Improving student modeling: the relationship between learning styles and cognitive traits (2005)

A challenge of student modeling in adaptive virtual learning environments is to get enough information about the learner. Information about the learner such as the domain competence, the learning style or the cognitive traits of a learner is very important for an adaptive environment to achieve its main aim, namely to adapt to the learners' needs. In this paper we investigate the interaction between learning styles, in particular the Felder-Silverman learning style model, and working memory capacity, a cognitive trait. As a result we demonstrate some relationship between learners with high working memory capacity and a reflective, intuitive, and sequential learning style whereas learners with low working memory capacity tend to prefer an active, sensing, visual, and global learning style. These interactions make it possible to improve student models.
Hexagonal lithium molybdate, LiMoO2: a close-packed layered structure with infinite molybdenum-molybdenum-bonded sheets (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHexagonal lithium molybdate, LiMoO2: a close-packed layered structure with infinite molybdenum-molybdenum-bonded sheetsLorraine E. Aleandri and Robert E. McCarleyCite this: Inorg. Chem. 1988, 27, 6, 1041–1044Publication Date (Print):March 1, 1988Publication History Published online1 May 2002Published inissue 1 March 1988https://pubs.acs.org/doi/10.1021/ic00279a021https://doi.org/10.1021/ic00279a021research-articleACS PublicationsRequest reuse permissionsArticle Views483Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts