gebhart/patrepeval huggingface dataset:
Sonochemical Stripping Voltammetry (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSonochemical Stripping VoltammetryNanette A. Madigan, Tammy J. Murphy, John M. Fortune, Carolynne R. S. Hagan, and Louis A. CouryCite this: Anal. Chem. 1995, 67, 17, 2781–2786Publication Date (Print):September 1, 1995Publication History Published online1 May 2002Published inissue 1 September 1995https://pubs.acs.org/doi/10.1021/ac00113a010https://doi.org/10.1021/ac00113a010research-articleACS PublicationsRequest reuse permissionsArticle Views237Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The functional significance of the autolysis loop in protein C and activated protein C (2005)

The autolysis loop of activated protein C (APC) is five residues longer than the autolysis loop of other vitamin K-dependent coagulation proteases. To investigate the role of this loop in the zymogenic and anticoagulant properties of the molecule, a protein C mutant was constructed in which the autolysis loop of the protein was replaced with the corresponding loop of factor X. The protein C mutant was activated by thrombin with approximately 5-fold higher rate in the presence of Ca2+. Both kinetics and direct binding studies revealed that the Ca2+ affinity of the mutant has been impaired approximately 3-fold. The result of a factor Va degradation assay revealed that the anticoagulant function of the mutant has been improved 4-5-fold in the absence but not in the presence of protein S. The improvement was due to a better recognition of both the P1-Arg506 and P1-Arg306 cleavage sites by the mutant protease. However, the plasma half-life of the mutant was markedly shortened due to faster inactivation by plasma serpins. These results suggest that the autolysis loop of protein C is critical for the Ca(2+)-dependence of activation by thrombin. Moreover, a longer autolysis loop in APC is not optimal for interaction with factor Va in the absence of protein S, but it contributes to the lack of serpin reactivity and longer half-life of the protease in plasma.
Cell patterning via diffraction-induced optoelectronic dielectrophoresis force on an organic photoconductive chip (2013)

A laser diffraction-induced dielectrophoresis (DEP) phenomenon for the patterning and manipulation of individual HepG2 cells and polystyrene beads via positive/negative DEP forces is reported in this paper. The optoelectronic substrate was fabricated using an organic photoconductive material, TiOPc, via a spin-coating process on an indium tin oxide glass surface. A piece of square aperture array grid grating was utilized to transform the collimating He-Ne laser beam into the multi-spot diffraction pattern which forms the virtual electrodes as the TiOPc-coating surface was illuminated by the multi-spot diffraction light pattern. HepG2 cells were trapped at the spot centers and polystyrene beads were trapped within the dim region of the illuminated image. The simulation results of light-induced electric field and a Fresnel diffraction image illustrated the distribution of trapped microparticles. The HepG2 morphology change, adhesion, and growth during a 5-day culture period demonstrated the cell viability through our manipulation. The power density inducing DEP phenomena, the characteristics of the thin TiOPc coating layer, the operating ac voltage/frequency, the sandwiched medium, the temperature rise due to the ac electric fields and the illuminating patterns are discussed in this paper. This concept of utilizing laser diffraction images to generate virtual electrodes on our TiOPc-based optoelectronic DEP chip extends the applications of optoelectronic dielectrophoretic manipulation.
Fish Attraction with Pulsed Low-Frequency Sound (1968)

A series of tests were conducted to determine the effectiveness of pulsed low-frequency acoustic signals for attracting fishes. The acoustic signals were contrived to simulate the hydrodynamically generated disturbances normally associated with active predation. Underwater television was used to observe fish arrivals during both control and test periods. Demersal predatory fishes were successfully attracted although they habituated rapidly to the acoustic stimulus. Members of the families Serranidae, Lutjanidae, and Pomadasyidae were particularly well represented among the fishes attracted. Sharks were also attracted in considerable numbers. Herbivorous reef fishes, although common around the test site, were not attracted. Possible relationships between the test results and the hearing capabilities of fishes are discussed. It is concluded that acoustic attraction techniques have potential applications in certain existing commercial fisheries.
Potassium, Cesium, and Ammonium Peroxogermanates with Inorganic Hexanuclear Peroxo Bridged Germanium Anion Isolated from Aqueous Solution (2015)

Potassium (K6[Ge6(μ-OO)6(μ-O)6(OH)6]·14H2O, 1), cesium ammonium (Cs4.2(NH4)1.8[Ge6(μ-OO)6(μ-O)6(OH)6]·8H2O, 2), and potassium ammonium (K2.4(NH4)3.6[Ge6(μ-OO)6(μ-O)6(OH)6]·6H2O, 3) peroxogermanates were isolated from 3% hydrogen peroxide aqueous solutions of the corresponding hydroxogermanates and characterized by single crystal and powder X-ray diffraction studies and by Raman spectroscopy and thermal analysis. The crystal structure of all three compounds consists of cations of potassium and/or ammonium and cesium, water molecules, and centrosymmetric hexanuclear peroxogermanate anion [Ge6(μ-OO)6(μ-O)6(OH)6](6-) with six μ-oxo- and six μ-peroxo groups. Peroxogermanates demonstrate relatively high thermal stability: the peroxide remains in the structure even after water release after heating to 100-120 °C. DFT calculations of the peroxogermanate [Ge6(μ-OO)6(μ-O)6(OH)6](6-) anion confirm its higher thermodynamic stability compared to the hydroperoxo- and oxogermanate analogues.
Real Time Implementation of Two Stage Search (2005)

Image matching is an important and well-known tech- nique for image processing and finds a variety of applications in computer vision, such as motion analy- sis, stereo vision,and scene registration. The inherent problem associated with the correlation matching is the high computational cost. In this paper an implemen- tation of modified two-stage search strategy is presen- ted. This method can speed up the search process and meet the requirements fop real time application.
A Modified Technique of Impression Cytology to Study the Fine Structure of Corneal Epithelium (1996)

In this article, the development and application of a modified technique of impression cytology for the electron-microscopic examination of corneal epithelium is presented. Corneal epithelium of controls and diabetic patients was obtained using millipore filters, which had been presoaked with EDTA to weaken intercellular adhesions. Light and electron microscopy (EM) of the control samples showed sheets of well-preserved corneal epithelial cells. Therefore, this modified technique is supposed to be useful for the analysis of alterations of the corneal epithelium. EM of corneal cells of diabetic patients showed irregularly formed epithelial cells. The corneal epithelium of diabetic patients revealed thickening of the basement membrane and a decreased number of hemidesmosomes. The alterations observed in specimens of diabetic patients represent the morphological equivalent of an impaired epithelial barrier function, an increased fragility of epithelial lining and the disturbed healing properties occurring in diabetic keratopathy.
Renal Metastasis from Prostatic Adenocarcinoma: A Potential Diagnostic Pitfall (1999)

We report a case of renal metastases from prostate cancer to show that the possibility of tumor metastasis, although rare, should always be considered in the differential diagnosis of renal mass.
Antiproliferative mechanisms of quercetin in rat activated hepatic stellate cells (2011)

Quercetin, rich in fruits and vegetables, has been used as a nutritional supplement because of its anti-inflammatory and antioxidative properties. Its positive effects on anti-hepatic fibrosis have also been suggested. However the anti-hepatofibrotic mechanisms upon which quercetin acts have yet to be well characterized. In the present study, we investigated the anti-proliferative effect of quercetin on activated hepatic stellate cells (aHSCs), the central role of hepatofibrosis, and evaluated the proteins involved in growth inhibition by a 2D gel electrophoretic analysis. Activated HSCs were isolated from Sprague Dawley rats and were spontaneously activated in vitro. Quercetin restrained the proliferation of aHSCs rather than quiescent HSCs and heptotcytes by inducing a G(1) arrest as examined by cell cycle analysis and evidenced by increased levels of p53, p21(CIP1/WAF1), as well as p27(KIP1), and decreased abundance of cyclins (D(1), D(2), A, E). An apoptosis through extrinsic pathway as demonstrated by elevated expression of Fas/Fas ligand (FasL), annexin V labeling, chromatin condensation, sub-G(1) fraction (7.39%), caspase-3 activity, was also observed. The 2D electrophoresis analysis revealed that quercetin negatively regulated protein molecules associated with metabolism (α-enolase, phosphoglycerate kinase), survival, cytokinesis (tubulin), and protein folding (protein disulfide isomerase A3) leading to cell growth retardation. Furthermore, quercetin might restrain HSC activation through reducing the levels of inflammatory cytokines (CXCL10, Midkine). Taken together, quercetin exerted diverse mechanisms to inhibit the growth of aHSCs. Proper consumption of quercetin could be beneficial to control the progression of heptofibrosis.
Tracking unmodified smartphones using wi-fi monitors (2012)

Smartphones with Wi-Fi enabled periodically transmit Wi-Fi messages, even when not associated to a network. In one 12-hour trial on a busy road (average daily traffic count 37,000 according to the state DOT), 7,000 unique devices were detected by a single road-side monitoring station, or about 1 device for every 5 vehicles.
Naturally Intelligent Systems (1992)

For centuries, people have been fascinated by the possibility of building an artificial system that behaves intelligently. Now there is a new entry in this arena - neural networks. Naturally Intelligent Systems offers a comprehensive introduction to these exciting systems. It provides a technically accurate, yet down-to-earth discussion of neural networks, clearly explaining the underlying concepts of key neural network designs, how they are trained, and why they work. Throughout, the authors present actual applications that illustrate neural networks' utility in the new world.
High Data-Rate Atom Interferometry for Measuring Dynamic Inertial Conditions (2015)

Light pulse atom interferometers have demonstrated remarkable sensitivity and stability for acceleration and rotation rate measurement. However, typical manifestations are designed for laboratory environments and thus rely on a fixed magnitude and direction of gravity, and limited ambient rotation rate. We have enhanced the application space of atom interferometers towards more dynamic environments, with special attention for inertial navigation. I present our work in the domain of short time-of-flight atom interferometry, whereby the magnitude of ensemble excursion is constrained. The limited interrogation time results in a significant loss of sensitivity. We recover a fraction of the lost sensitivity by operating with an enhanced duty-cycle and data-rate. To demonstrate this concept, we construct an atom interferometer accelerometer capable of operating at data-rates as high as 300 Hz with sensitivities at μg/rtHz levels, which represents a competitive figure for inertial navigation application. For the bulk of this work, we demonstrate a dual-axis sensor capable of simultaneous acceleration and rotation-rate measurements. The sensor relies on a technique we refer to as "ensemble exchange" which provides a high flux source of ultracold atoms by swapping atomic ensembles between two MOTs. We achieve a steady-state atom number of 7e6 atoms/shot using a minimal loading time of a few milliseconds each shot. Furthermore, we find this technique to be robust under dynamic conditions as large as 10 g of acceleration and 20 rad/s of rotation rate, representing a significant enhancement in ultra-cold atom sample preparation. The sensor achieves μg/rtHz and μrad/s/rtHz sensitivities, making this technique a compelling prospect for inertial navigation applications. Through the use of auxiliary cosensors and a real-time combinatorial loop with feedforward and feedback mechanisms, we demonstrate an unprecedented enhancement of the sensor dynamic range up to 20 mg. Finally, I will discuss a novel manifestation of short time-of-flight atom interferometry in a warm atomic vapor, which avoids the complication of cold sample preparation and has the potential for significantly simplified laser systems.
A Direct Catalytic Asymmetric Mannich-type Reaction to <i>syn</i>-Amino Alcohols (2002)

The Mannich reaction is one of the most widely utilized chemical transformations for the construction of nitrogen-containing compounds. With the increasing occurrence of nitrogen in drugs and natural products, highly asymmetric variants of the Mannich reaction are desirable. In this communication, we report the application of our dinuclear zinc catalyst to a highly asymmetric Mannich-type reaction to generate syn 1,2-amino alcohols.
[Changes of plasma B-type natriuretic peptide level during non-invasive ventilation in treating acute left heart failure]. (2008)

The plasma BNP level remarkably decreases in patients undergo non-invasive ventilation, suggesting that the plasma BNP level decreases along with the improvement of cardiac function.
Czech Culture in Prague: Architecture (2003)

Prague's main feature is that, out of many cultural treasures, it preserved its architectural culture and put it to practical use to present day. Particularly Prague has embraced a wealth of architectural styles from many ages. From the Romanesque, the Gothic culture of Czech's pinnacle age, Baroque, Neo Classicism, the Art Nouveau style buildings that concentrated in Prague at the end of 19th century and finally to modern structures. As we have studied, Prague is a textbook of historical styles: a Romanesque rotunda, a Gothic cathedral, a constellation of Baroque churches and palaces, a Renaissance summer palace, whole districts with histoicizing ‘neo-styles: neo-Gothic, neo-Renaissance, neo-Baroque, neo-Classic,’ Art Nouveau cafes, unfunctional pebble-stone streets and as yet undigested, isolated postmodern structure such as ‘Dancing Building-Gunger and Fred Building’ by Frank O. Gehry and Vlado Milinic
Memory Prefetching Using Adaptive Stream Detection (2006)

We present adaptive stream detection, a simple technique for modulating the aggressiveness of a stream prefetcher to match a workload's observed spatial locality. We use this concept to design a prefetcher that resides on an on-chip memory controller. The result is a prefetcher with small hardware costs that can exploit workloads with low amounts of spatial locality. Using highly accurate simulators for the IBM Power5+, we show that this prefetcher improves performance of the SPEC2006fp benchmarks by an average of 32.7% when compared against a Power5+ that performs no prefetching. On a set of 5 commercial benchmarks that have low spatial locality, this prefetcher improves performance by an average of 15.1%. When compared against a typical Power5+ that does perform processor-side prefetching, the average performance improvement of these benchmark suites is 10.2% and 8.4%. We also evaluate the power and energy impact of our technique. For the same benchmark suites, DRAM power consumption increases by less than 3%, while energy usage decreases by 9.8% and 8.2%, respectively. Moreover, the power consumption of the prefetcher itself is low; it is estimated to increase the power consumption of the Power5+ chip by 0.06%
Hydrogen Energy Progress VII (1989)

Papers presented at this conference covered: hydrogen production from fossil sources; electrolytic hydrogen production; thermochemical hydrogen production; photolytic hydrogen production; hydrogen in the chemical and fuel industries; hydrogen utilization in aircraft and turbines; hydrogen utilization in surface vehicles; hydrogen utilization in fuel cells; hydride technologies; hydrogen liquefaction; transport and storage; hydrogen programs and activities; hydrogen systems analysis; hydrogen markets and economics; safety; materials; and environmental issues. Five papers have been individually abstracted.
Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level (2017)

Hepatic miR-122 can serve as a pro-apoptotic factor to suppress tumorigenesis. The underlying mechanism, however, remains incompletely understood. Here we present the first evidence that miR-122 promotes hepatocellular carcinoma cell apoptosis through directly silencing the biogenesis of cell survival oncomiR miR-21 at posttranscriptional level. We find that miR-122 is strongly expressed in primary liver cell nucleus but its nuclear localization is markedly decreased in transformed cells particularly in chemoresistant tumor cells. MiRNA profiling and RT-qPCR confirm an inverse correlation between miR-122 and miR-21 in hepatocellular carcinoma tissues/cells, and increasing or decreasing nuclear level of miR-122 respectively reduces or increases miR-21 expression. Mechanistically, nuclear miR-122 suppresses miR-21 maturation via binding to a 19-nt UG-containing recognition element in the basal region of pri-miR-21 and preventing the Drosha-DGCR8 microprocessor's conversion of pri-miR-21 into pre-miR-21. Furthermore, both in vitro and in vivo studies demonstrate that nuclear miR-122 participates in the regulation of HCC cell apoptosis through modulating the miR-21-targeted programmed cell death 4 (PDCD4) signal pathway.
A digital signature scheme on a document for MH facsimile transmission (1991)

Abstract This paper proposes a digital signature scheme for a facsimile document which embeds a signature directly onto the document. The scheme modifies each run of white or black pixels with a single bit of the signature data. It is designed to be compatible with CCITT G3 facsimile standards and to protect the document from the insertion, modification, replacement, overwriting or deletion of characters. Furthermore, the total amount of data to be transmitted is about the same as that of the original facsimile document. In this paper, an authentication scheme is shown with a prototype model under a one‐key encryption system.
Preparation of La<sub>0.67</sub>Ca<sub>0.33</sub>MnO<sub>3</sub> Nanophase Powders and Films from Alkoxide Precursors (2002)

A sol−gel route has been developed which, as far as we know, is the first purely alkoxide-based route to nanophase powders and thin films of perovskite La0.67Ca0.33MnO3. The microstructural evolution, on heat treatment, of free gel films obtained by air hydrolysis of the methoxy-ethoxide precursors, to nanophase oxides of the target oxide was investigated by means of thermogravimetric analysis, differential thermal analysis, thermomass spectroscopy, FT-IR spectroscopy, powder X-ray diffraction, SEM-EDS, and TEM-EDS. The xero-gel consisted of a hydrated oxo-carbonate, almost without remaining solvent or alkoxo groups, and the metal elements appeared homogeneously distributed when studied with a ca. 20 nm wide EDS probe. Heating without annealing decomposed the carbonate groups and yielded the pure perovskite La0.67Ca0.33MnO3 at 690 and 800 °C, with heating rates of 5 and 20 °C min-1, respectively. The perovskite could also be obtained by annealing at 560 °C, but in this case there remained in the product a small amount of amorphous material containing La and Mn but almost no Ca. The orthorhombic La0.67Ca0.33MnO3 prepared by heating to 800 °C at rates of 20 °C min-1 or less had rather constant cell dimensions of ca. a = 5.45, b = 7.65, and c = 5.47 Å, while heating at 20 °C min-1 to 800 °C with 1 h annealing, heating at 2 °C min-1 to 800 °C without annealing, or heating at 20 °C min-1 to 1000 °C gave a cell with ca. a = 5.45, b = 7.71, and c = 5.47 Å, fitting the literature data quite well. The former cell is believed to have a higher Mn valency than the latter. Films were prepared by addition of a 0.6 M alkoxide solution to Si/SiO2/TiO2/Pt or polycrystalline α-Al2O3 substrates spinning at 3500 rpm, followed by heat treatment in air at 800 °C. Whereas crack-free, homogeneous 100−150 nm thick La0.67Ca0.33MnO3 films formed at heating rates of 20 °C min-1 or less, large bubbles were observed in films heated at 50 °C min-1 or more. Thicker films were obtained by repeating this procedure, and thinner films were obtained with more dilute alkoxide solutions.
Automated comparative sequence analysis identifies mutations in 89% of NF1 patients and confirms a mutation cluster in exons 11–17 distinct from the GAP related domain (2004)

N Neurofibromatosis type 1 (NF1) is a common auto- somal dominant genetic disorder caused by mutations in the NF1 gene. Mutation detection in NF1 has been a major challenge due to the large size of the gene and lack of mutational hotspots.
Surface Modification Studies of Polyimide Films Using Rutherford Backscattering and Forward Recoil Spectrometry (1996)

We followed the surface imide ring hydrolysis of fully imidized polyimide films by aqueous base solutions using Rutherford backscattering spectrometry. The hydrolysis reaction was studied using several different polyimide films including spuncast and thermally imidized PMDA-ODA, Kapton-H, and Upilex-S films. The boundary between the modified layer at the surface and the underlying film is a sharp front behind which the conversion of the polyimide into poly(amic acid) is complete and ahead of which there is almost no hydrolysis. The modified layer grows linearly with the time it is exposed to the basic solution. The growth velocity increased strongly with increases in the temperature of the basic solution. Under the reasonable hypothesis that the growth of the modified layer is controlled by the kinetics of the hydrolysis of the imide ring at the interface, we extract an activation energy for this process in Kapton-H films of 60 kJ/mol as compared to 68 kJ/mol for Upilex-S. Using forward recoil spectrometry, we studied the amount of interpenetration when a second layer of deuterium-labeled poly(amic acid) was spun-cast onto the surface-modified PMDA/ODA film. We determined that the interface between the spun-cast layer and the base layer is broader when the modification depth is greater. The fracture energy of such an interface, as measured with a T-peel test, rises rapidly as a function of modification depth and saturates at a value ∼20 times the value for an interface formed from PMDA/ODA polyimide with an unmodified surface.