gebhart/patrepeval huggingface dataset:
Mechanism of a Directly Observed .beta.-Hydride Elimination Process of Iridium Alkoxo Complexes (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of a Directly Observed .beta.-Hydride Elimination Process of Iridium Alkoxo ComplexesOfer Blum and David MilsteinCite this: J. Am. Chem. Soc. 1995, 117, 16, 4582–4594Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://pubs.acs.org/doi/10.1021/ja00121a016https://doi.org/10.1021/ja00121a016research-articleACS PublicationsRequest reuse permissionsArticle Views1426Altmetric-Citations111LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Differential recognition of members of the carcinoembryonic antigen family by Afa/Dr adhesins of diffusely adhering <i>Escherichia coli</i> (Afa/Dr DAEC) (2004)

Little is known about the molecular bases underlying the virulence of diffusely adhering Escherichia coli (DAEC) harbouring the Afa/Dr family of adhesins. These adhesins recognize as receptors the GPI-anchored proteins CD55 (decay-accelerating factor, DAF) and CD66e (carcinoembryonic antigen, CEA). CD66e is a member of the CEA-related cell adhesion molecules (CEACAM) family, comprising seven members. We analysed the interactions of Afa/Dr DAEC with the CEACAMs using CEACAM-expressing CHO and HeLa cells. The results demonstrate that only E. coli expressing a subfamily of Afa/Dr adhesins, named here Afa/Dr-I, including Dr, F1845 and AfaE-III adhesins, bound onto CHO cells expressing CEACAM1, CEA or CEACAM6. Whereas all the Afa/Dr adhesins elicit recruitment of CD55 around adhering bacteria, only the Afa/Dr-I subfamily elicits the recruitment of CEACAM1, CEA and CEACAM6. In addition, although CEACAM3 is not recognized as a receptor by the subfamily of Afa/Dr adhesins, it is recruited around bacteria in HeLa cells. The recruited CEACAM1, CEA and CEACAM6 around adhering bacteria resist totally or in part a detergent extraction, whereas the recruited CEACAM3 does not. Finally, the results show that recognition of CEA and CEACAM6, but not CEACAM1, is accompanied by tight attachment to bacteria of cell surface microvilli-like extensions, which are elongated. Moreover, recognition of CEA is accompanied by an activation of the Rho GTPase Cdc42 and by a phosphorylation of ERM, which in turn elicit the observed cell surface microvilli-like extensions.
Risks to the public in computers and related systems (2005)

Edited by Peter G. Neumann (Risks Forum Moderator and Chairman of the ACM Committee on Computers and Public Policy), plus personal contributions by others, as indicated. Opinions expressed are individual rather than organizational, and all of the usual disclaimers apply. We address problems relating to software, hardware, people, and other circumstances that affect computer systems. To economize on space, we tersify most items and include pointers to items in the online Risks Forum: (R i j) denotes RISKS vol i number j. Cited RISKS items generally identify contributors and sources, together with URLs. Official RISKS archives are available at www.risks.org (which redirects to Newcastle and gets you nice html formatting and a search engine courtesy of Lindsay Marshall; http://catless.ncl.ac.uk/Risks/i.j.html gets you (R i j)) and at ftp://www.sri.com/risks.
Telomerase in cancer: Clinical applications (1998)

The biology of telomeres and telomerase has been the subject of intensive investigative effort since it became evident that they play a significant role in two important biological processes, the loss of cellular replicative capacity inherent to organismal ageing and the unrestricted cell proliferation characteristic of carcinogenesis. Telomere shortening in normal cells is a result of DNA replication events, and reduction beyond a critical length is a signal for cellular senescence. One of the cellular mechanisms used to overcome proliferative restriction is the activation of the enzyme telomerase, which replaces the loss of telomeric DNA that occurs at each cell division. Studies have demonstrated that tumours have shorter telomeres than normal tissue and that telomerase is activated in up to 90% of all human cancers while it is present only in a limited range of normal adult tissues. The role of telomerase in the extension of the cellular replicative lifespan has recently been shown by ectopic expression of the enzyme, being consistent with the oncogenesis model whereby the acquisition of an 'immortal' phenotype is a requirement for advanced tumour progression. In this article we review the present knowledge of telomeres and telomerase in cancer and discuss the potential use of this enzyme as a diagnostic and prognostic tumour marker and as a target for cancer therapy.
Device parameter variations of n-MOSFETS with dog-bone layouts in 65nm and 40nm technologies (2013)

In this paper, variations of device parameters, such as threshold voltage (Vth) and saturation current (Idsat), of the devices with and without dog-bone-shaped active-area are investigated with a set of test structures in both 65nm and 40nm CMOS technology processes, respectively. The experiments show that variations of Vth/Idsat of dog-bone devices are more serious than the non-dog-bone device. At 65nm technology node, the inter-die absolute variation of the measured Idsat of dog-bone devices can reach 19.51% while that of standard devices is 11.31%. At 40nm technology node, the inter-die absolute variation of the measured Idsat of dog-bone devices can reach 21.29% while that of non-dog-bone devices is 15.11%. Moreover, the maximum intra-die performance deviation of dog-bone devices from standard devices can be 24% at a 65nm technology and about 42% at a 40nm technology. SPICE simulations show that the device performance variation is mainly due to the channel-width difference caused by photolithography effect. Therefore, it is very important to study both design-for-manufacturability (DFM) and resolution-enhancement-technology (RET) techniques to optimize the design and fabrication of dog-bone devices for IC designs in 65nm and below processes.
Spontaneous Regression of an Unruptured and Non-Giant Intracranial Aneurysm (2012)

It is well known that spontaneous thrombosis in giant cerebral aneurysm is common. However, spontaneous obliteration of a non-giant and unruptured cerebral aneurysm has been reported to be rare and its pathogenic mechanism is not clear. We describe a case with rare vascular phenomenon and review the relevant literatures.
Life satisfaction, self-concept, and family relations in Chinese adolescents and children (2003)

Subjective well-being across the life span may be affected by both age-specific and age-general factors within a cultural context. Thus, this study explored both developmentally invariant and variable predictors of life satisfaction among 115 second-graders and 74 eighth-graders from Hong Kong. In a regression model, general self-concept and ratings of parental warmth and autonomy/detachment predicted life satisfaction equally across the two age groups. However, social self-concept was a strong predictor of life satisfaction among adolescents only, whereas actual academic test scores predicted life satisfaction only among the children. Mean group differences emerged as well, with adolescents scoring significantly lower in life satisfaction and self-concept and higher in emotional detachment than children. Results are explained in relation to both development and culture.
Modified dynamic hashing (1985)

Article Free Access Share on Modified dynamic hashing Author: Kyoji Kawagoe C&C Systems Research Laboratories, NEC Corporation, Miyamae, Kawasaki, Kanagawa 213, Japan and Computer Science Research Department, Lawrence Berkeley Laboratory, University of California C&C Systems Research Laboratories, NEC Corporation, Miyamae, Kawasaki, Kanagawa 213, Japan and Computer Science Research Department, Lawrence Berkeley Laboratory, University of CaliforniaView Profile Authors Info & Claims SIGMOD '85: Proceedings of the 1985 ACM SIGMOD international conference on Management of dataMay 1985 Pages 201–213https://doi.org/10.1145/318898.318917Online:01 May 1985Publication History 3citation421DownloadsMetricsTotal Citations3Total Downloads421Last 12 Months57Last 6 weeks11 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Managing Software Assets in a Global Enterprise (2011)

The IBM Corp invents, develops and manufactures IT products, including computer systems and software, system networks, storage hardware and microelectronic products. The IBM CIO Global Infrastructure Architecture and Strategy (CIO GIAS) team is responsible for running and optimizing IBM's internal IT operations which include more than 500,000 users connecting to over 20,000 servers across 170 countries. The solution described below, implemented between 2008-2010, is a response to managing software licenses in one of the world's largest distributed enterprises.
Do.–Sep. 15, 1809 (2011)

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Acidic pH‐Responsive siRNA Conjugate for Reversible Carrier Stability and Accelerated Endosomal Escape with Reduced IFNα‐Associated Immune Response (2013)

An siRNA conjugate is based on an acid-labile maleic acid amide linkage for programmed transfer of siRNA from the endosome to the cytosol and siRNA release in the cell interior. The procedure relies on reversible stability in response to endosomal acidic pH value. The complexed polyionic conjugate achieved gene silencing in cultured cancerous cells with negligible side effects. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Sustainable Economy of Ecological Footprint in Africa: An Economic Analysis and Impacts (2013)

Eco logical footprint is an important measure in calculat ing the human demands and impacts on our global environment. In th is respect the ecological footprint is a function of all the parameters that interact between the power of ecosystem productivity and human interactions and activities on a particular ecosystem or the demand fro m that ecosystem. The present paper will cover and analyze the ecosystems productivity and the human demand from the ecosystems of African continent. It will produce co mprehensive analyses in measuring the possibility of capabilities of the ecosystems in Africa to provide goods and services to the human beings who are liv ing on African continent. Further, the paper will d iscuss the models that can be used in measuring the sustainability of ecosystem and what we should be doing to maintain the African healthy ecosystems. In this respect, the paper will assess and introduce a comprehensive model that can describe the status of African ecosystems productivities and the impacts of human population on the African continent. Furthermore, the paper will provide some answers to the human issues in Africa, further warn ing to the current trend in use and abuse of our natural ecosystems in Africa and what will be expecting fro m these ecosystems to provide the human needs in response to the current use of our global ecosystems. Finally, it will conclude and setup several recommendations to save the African Continent ecosystems fro m the irreversible impacts of human beings on these ecosystems and also for global environ ment.
Organic Reactions in Ionic Liquids: Knoevenagel Condensation Catalyzed by Ethylenediammonium Diacetate (2003)

The moisture and air stable ionic liquids 1-butyl-3-methylimidazonium tetrafluoroborate [bmim]BF4 and 1-butyl-3-methylimidazonium hexafluorophosphate [bmim]PF6 were used as 'green' recyclable alternatives to volatile organic solvents (VOCs) for ethylenediammonium diacetate (EDDA) catalyzed Knoevenagel condensation between aldehydes or ketones with active methylene compounds. Both aldehydes and ketones gave satisfactory results. The ionic liquids containing catalyst EDDA were recycled several times with no decreases in yields and reaction rates. In the case of 2-hydroxybenzaldehyde, the reactions led to the formation of 3-substituted coumarins under standard reaction conditions.
Improved syntheses of benzils as polymer intermediates (1981)

Abstract Methods of synthesis of benzils were considered and some new combinations of old reactions were developed to make these materials more readily available as polymer intermediates.
Primary Striatal Neuronal Culture (2003)

The incredible in vivo complexity of nervous system and activity oftentimes prevents the neuroscientist from attempting to understand how individual neural cells or a specific phenotype of neural cells contribute to a given function of the nervous system. To elucidate intercellular and intracellular mechanisms, the complexity therefore needs to be reduced experimentally. Primary neural culture is an in vitro approach attempting to reduce this complexity, and establishes a relatively purified model for studying the nervous system at a single cell level. Because the culture environment can be readily controlled, neural cultures can be set up to possess biological properties similar or distinct to the original tissue. Research data from the culture study can therefore be valuable to predict the behavior of specific neural cells in vivo.
A quantitative comparison of t-cell subsets in hodgkin's disease and reactive hyperplasia frozen section immunohistochemistry (1984)

Cryostat sections of lymph nodes from patients with Hodgkin's disease were stained with monoclonal antibodies reactive with T-cells including T-cell subsets. Lymph nodes showing reactive hyperplasia were used as controls. Using an eyepiece grid, the stained cells were counted and subset ratios determined. The ratio of helper T-cells to cytotoxic/suppressor T-cells, i.e., (formula; see text) in Hodgkin's disease was found to be significantly different from ratios obtained from reactive nodes. This difference may be explained by a relative increase in cytotoxic/suppressor T-cells and/or a decrease in helper T-cells. This finding may relate to the previously reported increase in suppressor cell activity in patients with Hodgkin's disease and may also correlate with diminished delayed-type hypersensitivity in such patients.
Clinical significance of expression and epigenetic profiling of<i>TUSC1</i>in gastric cancer (2014)

Our results suggested that reduced expression of TUSC1 mRNA was related to poor prognosis and TUSC1 is a putative TSG that is suppressed through intragenic hypermethylation in GC.
CT spectral projection imaging (2009)

Dual energy x-ray computed tomography (DECT) has gained a significant attention in recent years. The technology offers the potential to differentiate different materials, and therefore provides the possibility of identifying different pathologies. In this paper, we present a dual-energy projection imaging technique by utilizing the scout data acquisition mode of CT in conjunction with the fast-kVp switching capability. Phantom experiments have shown its advantage in removing overlapping structures and improves the visualization of small structure inside the body.
Expression of cytokines and receptors in normal, immortalized, and malignant ovarian epithelial cell lines. (2003)

Ovarian cancer cells produce more cytokines than normal HOSE cells. Immortalized HOSE cells display a cytokine profile similar to the cancer cells. Finally, multiple autocrine loops in ovarian cancer may limit the therapeutic usefulness of single cytokine receptor blockade.
A new cell culture assy for quality control in IVF (1989)

A new, simple and sensitive bioassay for quality testing in IVF is described. This bioassay (Medi-Cult Hybritest, GEA Ltd, Biotech Division, Hvidovre, Denmark) is based on the culture of the rapidly growing mouse hybridoma cell line 1E6 in a defined serum-free culture medium. The use of serum-free conditions greatly increases the sensitivity to toxic substances, due to the absence of binding proteins. The testing of known toxic agents showed that this assay disclosed cytotoxicity with a high sensitivity. The Hybritest thus provides a simple yet sensitive and reproducible bioassay for quality control of culture media, water, chemical compounds and equipment in an IVF programme. Tests of different batches of culture media showed that media for IVF should be processed from powder and high-quality sterile water. It is important not only to test the single components of the culture media, but also the final product in a sensitive test system.
Organic nonvolatile memory by dopant-configurable polymer (2006)

We report an organic, nonvolatile memory based on dopant concentration-induced conductance changes in a conjugated polymer. Consisting of a polymer poly [2-methoxy-5-(2′-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV)/ionic conductor (RbAg4I5) bilayer sandwiched between two metal electrodes, the device is electrically switched between its low-conductance “off” state and high-conductance “on” state reversibly and repeatedly with on/off ratios above two orders of magnitude and pulse durations as short as 1μs when a voltage exceeding its threshold values (&gt;+3.5V or &lt;−3.8V) is applied. The conductance change is attributed to the injection/depletion of iodide dopant ions in the MEH-PPV layer by the applied electric field.
STRUCTURE OF AN ARABINOGALACTAN FROM TAMARACK (LARIX LARICINA) (1961)

Partial acid hydrolysis of an arabinogalactan from tamarack wood yielded:(I) L-arabinose,(II) D-galactose,(III) 3-O-β-L-arabinopyranosyl-L-arabinose,(IV) 6-O-β-D-galactopyranosyl-D-galactose,(V) 3-O-β-D-galactopyranosyl-D-galactose,(VI) O-D-galactopyranosyl(1 → 6)-O-D-galactopyranosyl(1 → 6)-D-galactose,(VII) 3,6-di-O-(galactopyranosyl)-D-galactopyranose,(VIII) O-D-galactopyranosyl(1 → 3)-O-D-galactopyranosyl(1 → 3)-D-galactose,(IX) O-D-galactopyranosyl(1 → 6)-O-D-galactopyranosyl(1 → 3)-D-galactose,(X) O-D-galactopyranosyl(1 → 6)-O-D-galactopyranosyl(1 → 6)-O-D-galactopyranosyl(1 → 3)-D-galactose,(XI) O-D-galactopyranosyl(1 → 6)-O-D-galactopyranosyl(1 → 3)-O-D-galactopyranosyl(1 → 3)-D-galactose.A previously published structure for the tamarack polysaccharide was revised to show that not more than two consecutive 1 → 3 or 1 → 6 linkages respectively were present in the main core of the repeating unit. Some of the 6-O-β-D-galactopyranosyl-D-galactose units occurred as side chains as well as in the main body of the molecule.
Bispectrum analysis of EEG of a dog to determine the depth under halothane anesthesia (2002)

The solution of the problem of finding the depth of anesthesia or the level of unconsciousness by monitoring the electroencephalogram (EEG) is considered. The bispectrum analysis of the EEG of a dog is studied to determine any trends with increasing depth of anesthesia. Of the four channels of EEG analyzed, channel 1 (L/sub r/-L/sub 0/) seems to show a strong coupling between frequencies in the range of 6-10 Hz around 78% of the time when the dog is asleep (depth = 1.0) and a weak or no coupling between frequencies in the same range around 67% of the time when the dog is awake (depth = 0.0).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Real-Time 3-D Object Classification Using a Learning System (1987)

We describe some experiments in real-time 3-D object classification using a learning system derived from a general neural model for supervised learning. The primary advantages of the learning system are its ability to learn from experience to recognize patterns and its inherent massive parallelism. Our motivation is to examine the feasibility and merits of the learning system in a simple machine vision problem.
Spectrophotometric Study of Platinum(IV)-Tin(II) Chloride System (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrophotometric Study of Platinum(IV)-Tin(II) Chloride SystemG. H. Ayres and A. S. MeyerCite this: Anal. Chem. 1951, 23, 2, 299–304Publication Date (Print):February 1, 1951Publication History Published online1 May 2002Published inissue 1 February 1951https://pubs.acs.org/doi/10.1021/ac60050a020https://doi.org/10.1021/ac60050a020research-articleACS PublicationsRequest reuse permissionsArticle Views366Altmetric-Citations97LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Quantitative microfocal radiography detects changes in OA knee joint space width in patients in placebo controlled trial of NSAID therapy. (1995)

Using microfocal radiography the time course of changes in JSW and osteophyte size of knees with early, but not late OA, was found to differ in both pattern and magnitude in patients receiving NSAID: In knees with late stage OA the JSW progressively decreased irrespective of treatment. The observations may prove useful for the design of future therapeutic trials.