gebhart/patrepeval huggingface dataset:
THE GENETICS OF THE GONOCOCCUS (1984)

Despite the inherent limitations imposed by working with an organism that still has a very limited genetic map and relatively few systems for manipulation of the genome, much has been learned in the past decade. Recent applications of the technology of monoclonal antibodies and recombinant DNA, coupled with careful studies of the immunobiology of pili and various outer membrane structures have provided exciting insights into the molecular pathogenesis of gonococcal infections. One of the principal lessons is the sophistication of the gonococcal strategies for evading the host defenses, including high-frequency variations of pili and P.II and an extracellular protease for specific cleavage of IgA1. It is unclear how much antigenic variation will limit vaccine development. Regardless, the pursuit of a vaccine has led to important new fundamental knowledge of the genetics and structure-function relationships of several cell surface components, and the future promises to be both rational and interesting.
[Effect of soybean lipoxygenae on baking properties of wheat flour]. (2011)

Changes in bread-baking properties of wheat flour caused by soybean lipoxygenase and polyunsaturated fatty acids were studied. A positive effect of soybean flour added during dough kneading in an amount of 2% was demonstrated. A method for dough fermentation increasing the loaf volume and improving organoleptic characteristics and total bread-baking estimate is recommended.
Modeling an Expository Text Structure Strategy in Think Alouds (1990)

Several current notions used in combination can contribute to better teaching of comprehension of expository text. These include knowledge of text structure, strategic reading, and the think-aloud procedure. Knowledge of text structure is knowledge of the author's underlying organization of the ideas presented. The think-aloud procedure is suggested as the vehicle by which to demonstrate a strategic readers' use of text structure knowledge while reading. It's a "talk-as-you go" or "talk-as-you read" procedure. Strategies are defined as systematic plans that readers can use flexibly, adapting them to particular reading situations or contexts (Duffy and Roehler, 1987). Strategies are thus generalizable beyond any one task.
An Extremal Theorem in the Hypercube (2010)

The hypercube $Q_n$ is the graph whose vertex set is $\{0,1\}^n$ and where two vertices are adjacent if they differ in exactly one coordinate. For any subgraph $H$ of the cube, let $\textrm{ex}(Q_n, H)$ be the maximum number of edges in a subgraph of $Q_n$ which does not contain a copy of $H$. We find a wide class of subgraphs $H$, including all previously known examples, for which $\textrm{ex}(Q_n, H) = o(e(Q_n))$. In particular, our method gives a unified approach to proving that $\textrm{ex}(Q_n, C_{2t}) = o(e(Q_n))$ for all $t \geq 4$ other than $5$.
Molecular identification of the liver- and the heart-type fatty acid-binding proteins in human and rat kidney. Use of the reverse transcriptase polymerase chain reaction (1992)

The cDNAs of two types of fatty acid-binding protein (FABP) present in human kidney, previously described as types A and B, were isolated using reverse transcriptase-PCR (RT-PCR) with human kidney mRNA and various sets of primers. The cDNA fragments were cloned and sequenced. Renal FABP type A and B cDNAs appeared to be completely identical to human liver- and heart-type FABP cDNAs respectively. In the second part of this study we demonstrated the presence of liver-type FABP in rat kidney by chromatography, e.l.i.s.a. and immunocytochemistry. The ratio and cellular distribution of the two FABP types varies markedly in human and rat kidney. Using RT-PCR we were also able to prepare and identify liver- and heart-type FABP cDNAs with mRNA from both male and female rat kidney.
Robust header compression (ROHC) in next-generation network processors (2005)

Robust Header Compression (ROHC) provides for more efficient use of radio links for wireless communication in a packet switched network. Due to its potential advantages in the wireless access area and the proliferation of network processors in access infrastructure, there exists a need to understand the resource requirements and architectural implications of implementing ROHC in this environment. We present an analysis of the primary functional blocks of ROHC and extract the architectural implications on next-generation network processor design for wireless access. The discussion focuses on memory space and bandwidth dimensioning as well as processing resource budgets. We conclude with an examination of resource consumption and potential performance gains achievable by offloading computationally intensive ROHC functions to application specific hardware assists. We explore the design tradeoffs for hardware assists in the form of reconfigurable hardware, Application-Specific Instruction-set Processors (ASIPs), and Application-Specific Integrated Circuits (ASICs).
Improving the efficiency of Sammon's nonlinear mapping by using clustering archetypes (1978)

Sammon's nonlinear mapping technique is discussed and certain inefficiencies are highlighted. It is shown how the algorithm can be streamlined by using appropriately chosen cluster archetypes. This results in reductions in storage requirements and in execution time, the latter by at least an order of magnitude.
Immunotherapy of tularemia: characterization of a monoclonal antibody reactive with <i>Francisella tularensis</i> (1993)

An IgM monoclonal antibody (mAb) recognized surface antigens specific to Francisella tularensis wild-type (Schu4) and live vaccine strain (LVS), and reacted with both in ELISA and slide agglutination tests. This mAb also reacted with LVS microorganisms in tissues of infected mice as assessed by an indirect fluorescence technique. Western blot analysis showed the mAb to react with antigens associated with F. tularensis LPS.
Bridging the gap between the digital and real worlds: the expanding role of analog interface technologies (2003)

The dramatic evolution of semiconductor technology over the last 50 years caused a real industrial and social revolution that is ongoing today. The progress from single-transistor to ULSI circuits has been very fast. As technology proceeded according to the well-known Moore's Law, circuit-design techniques moved more and more from analog to digital following the continuous progress made in microlithography. While there has been a corresponding huge increase in the computing power of digital circuits, this has not been accompanied by a comparable evolution in the capability of integrated circuits to interface to the external world. For free-standing computers, speed is the key factor. In other applications such as mobile phones, the interfaces with the external world are fundamental and provide the driving force in the evolution of these products. Technologies like BiCMOS, HVCMOS and BCD, which are already available and will further evolve in the future, appear to be more suitable than pure CMOS in satisfying those needs. We are moving now to SoC (System on Chip) and in the future to SiP (System in Package) techniques that will very likely include micromachined technologies. In this paper, both recent and future developments in analog interfaces will be analyzed, with particular attention given to the problem of power-consumption reduction in portable devices. As well, an overview of new applications of MEMS devices will be presented.
Saunders manual of nursing care (1997)

Unit I: Challenges Facing Nurses in the 1990s and Beyond. Problem Solving in Nursing. Providing Transcultural Nursing Care. Managing the Modern Environment. Unit II: Performing a Holistic Health Assessment. Obtaining the Basic Health History. Performing the Basic Physical Assessment. Performing the Basic Psychosocial Assessment. Unit III: Caring for People with Medical-Surgical Needs and Problems. Caring for People with Disabilities. Caring for People with Infections and Infectious Disorders. Caring for People with Fluid, Electrolyte, And Acid-Base Imbalances. Caring for People with Nutritional Disorders. Caring for People in Pain. Caring for People in Shock. Caring for People Undergoing Surgery. Unit IV: Caring for People with Special Developmental Needs and Problems. Caring for Families in the Childbearing Cycle. Caring for Infants, Children, And Adolescents. Caring for Older People. Unit V: Caring for People with Medical-Surgical Disorders. Caring for People with Cancer. Caring for People with Neurologic Disorders. Caring for People with Visual Disorders. Caring for People with Ear, Nose, Throat, Head and Neck Disorders. Caring for People with Immune and Auto-Immune Disorders. Caring for People with Respiratory Disorders. Caring for People with Cardiovascular Disorders. Caring for People with Peripheral Vascular and Lymphatic Disorders. Caring for People with Blood Disorders. Caring for People with Urinary System Disorders. Caring for People with Gastrointestinal Disorders. Caring for People with Hepatic, Biliary, And Pancreatic Disorders. Caring for People with Endocrine Disorders. Caring for Men with Sexual and Reproductive System Disorders. Caring for Women with Sexual and Reproductive System Disorders. Caring for People with Sexually Transmitted Diseases. Caring for People with Breast Disorders. Caring for People with Musculoskeletal Disorders. Caring for People with Integumentary Disorders. Caring for People with Burn Injuries. Caring for People Experiencing Emergencies. Caring for People with Environmentally and Occupationally Induced Disorders. Unit VI: Caring for People with Special Psychosocial Needs and Problems. Caring for People Experiencing Life Crises. Caring for People with Tobacco, Alcohol, And Other Drug Addictions. Caring for People with Mental Disorders. Caring for People with HIV Disease. Caring for People Who Are Dying and Their Families. Appendix A: Traditional Health Benefits and Practices of Selected Cultures. Appendix B: Guidelines for Obtaining Specific Laboratory Cultures. Appendix C: Clinical Laboratory Values. Appendix D: Guidelines for Isolation Precautions in Hospitals.
Floating Mirrors (1999)

We discuss a new technology that promises large, inexpensive mirrors. We argue that it should be possible to tilt a rotating viscous liquid by perhaps as much as a few tens of degrees. The tilted liquid parabolic surface is used as the support for a thin reflecting metallic film. It may also be possible to use it to support an ultrathin glass mirror. We demonstrate two critical steps: that a viscous liquid mirror can be tilted and that an optical-quality metallic film can be deposited on a liquid. The advent of astronomically useful tilted floating-mirror telescopes is contingent on the development of high-viscosity, high-reflectivity liquids. It is a good omen that we already have identified two classes of such liquids; however, there remain technical challenges to overcome before such liquids can be used in viable telescopes.
Study of Corrosion Prevention at Initial Condensate in Crude Oil Fractionator Overhead System (Part 1) (1970)

Corrosion at overhead lines and condensers of a crude oil fractionator is caused mainly by dissolution of acidic substances into condensed water. To prevent this corrosion, both neutralization of the acidic substances with ammonia and formation of protective layers with filming amines have usually been practiced. Sufficient prevention of the corrosion, however, has not been achieved with the neutralization with ammonia. This paper deals with laboratory-scale experiments concerning behaviors of hydrogen chloride and hydrogen sulfide in the initial condensate and neutralization with ammonia. The results of the experiments are summarized as follow:1. Hydrogen chloride is easily absorbed in the initial condensate and is highly concentrated in it.2. Ammonia has far less tendency to be absorbed in the initial condensate.3. Ammonium chloride is hydrolyzed in the initial condensate, lowering the pH of the initial condensate.4. To effectively neutralize acidic substances in the initial condensate, the alkali should be of such properties that it dissolves readily in the condensate and the neutralization product is not hydrolyzed. Kuritop 101 has been developed to satisfy these conditions.
Prevention of Hypertension, Cardiovascular Damage and Endothelial Dysfunction with Green Tea Extracts (2007)

The GTE prevented hypertension and target organ damage induced by a high Ang II dose, likely by prevention or scavenging of superoxide anion generation.
Retained cocaine conditioned place preference in D1 receptor deficient mice (1995)

The role of the D1 dopamine receptor subtype in mediating cocaine effects was examined in mice in which the D1 receptor gene had been ablated by homologous recombination. Cocaine reward was assessed by conditioned place preference experiments using mice which had either one allele (+/-) or both alleles (-/-) of the D1 dopamine receptor gene disrupted and in their wild type (+/+) littermates. Cocaine conditioning resulted in similar increases in preference for drug-paired environments in mice of each of the three genotypes. Cocaine did not alter locomotor activity levels in homozygous, D1 knockout mice -/-, whereas increased activity was noted in both +/+ and +/- animals. These results are consistent with the idea that the D1 receptor is involved in the locomotor stimulant effects of cocaine, but has little role in a major test of the rewarding and reinforcing effects of the drug.
Receptor Radionuclide Therapy with 90Y-[DOTA0]-Tyr3-Octreotide (90Y-DOTATOC): The IEO Experience (2013)

High concentrations of subtype 2 somatostatin tumor receptors are expressed in numerous tumors, enabling primary and metastatic masses to be localized by scintigraphy after injecting 111In-labeled somatostatin analogue octreotide. Receptor radionuclide therapy consists in the intravenous administration ofa peptide, such as octreotide, labelled with a therapeutic radionuclide. The basis for receptor radionuclide therapy with radiolabelled octreotide in somatostatin receptor rich tissues is the receptor-mediated endocytosis of the radiopeptide that is trapped inside the cytoplasm, thus allowing the irradiation of the cell. Dosimetric studies indicate that 90Y-[DOTA]0-Tyr3-Octreotide (90Y-DOTATOC) is suitable for efficient receptor radiotherapy. 90Y-DOTATOC therapy has proven to be a safe and effective treatment. Possible toxicity deriving from 90Y-DOTATOC therapy may be divided in to acute and delayed. Probably the radius of beta emission of the radioisotope has to fit the tumor dimension. Therefore, the administration of combinations of radioisotopes for different sized lesions should be evaluated in future studies.
Packing in two and three dimensions (2003)

This dissertation investigates Multidimensional Packing Problems (MD-PPs): the Pallet Loading Problem (PLP), the Multidimensional Knapsack Problem (MD-KP), and the Multidimensional Bin Packing Problem (MD-BPP). In these problems, there is a set of items, with rectangular dimensions, and a set of large containers, or bins, also with rectangular dimensions. Items cannot overlap (share the same region in space), and, when packed, must be completely located within the bin. We develop new theory for PLP, and apply it to the construction of new bounds, heuristics, and an exact algorithm. The bounds verify that the heuristics optimally solve 99.999% of PLP instances with up to 100 items; in the instances that the heuristics fail to solve optimally, their best solution differs from the optimum by only one item. Using our new PLP theory, we implement algorithms to solve orthogonal non-guillotine MD-KP instances and are the first to obtain exact solutions for some instances from the literature. Using these MD-KP algorithms, we develop the first exact algorithm for the orthogonal nonguillotine MD-BPP and are the first to obtain exact solutions to several instances from the literature.
Formation of Triniobocene Cationic and Neutral Mononiobocene Species as a Function of Solvent in the Reaction of Cp<sub>2</sub>Nb{(μ-H)<sub>2</sub>BR<sub>2</sub>} (R<sub>2</sub> = C<sub>4</sub>H<sub>8</sub>, C<sub>5</sub>H<sub>10</sub>, C<sub>8</sub>H<sub>14</sub>) with B(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub> (2001)

Reactions of the niobocene cyclic organohydroborates Cp2Nb{(μ-H)2BR2} (R2 = C4H8, C5H10, C8H14), with B(C6F5)3 in the poorly coordinating solvent toluene and in the coordinating solvent diethyl ether give different products. In toluene, the salt [Cp2Nb(μ-H)(η5-η1-C5H4)Nb(η5-η1-C5H4)2Nb{(μ-H)(η5-C5H4B(C6F5)2)}]+[HB(C6F5)3]-, 1, which contains a triniobocene cation, is formed. On the other hand in diethyl ether, the reaction of Cp2Nb{(μ-H)2BR2} with B(C6F5)3 produces the covalent complex CpNb(C6F5){(μ-H)(η5-C5H4B(C6F5)2)}, 2. In the formation of these compounds NbIII is oxidized to NbIV. Upon the basis of ESR spectra, 1 and 2 are paramagnetic, each with one unpaired electron. The structures of 1 and 2 were determined by single-crystal X-ray analysis. Complex 2 forms weak adducts in the solvents THF and pyridine. The Nb−H−B bridge is cleaved at the Nb−H site to form CpNb(C6F5)(L){η5-C5H4B(H)(C6F5)2} (L = THF, pyridine). In pyridine, a second adduct in much smaller yield is also formed, CpNb(C6F5)(H){η5-C5H4B(Py)(C6F5)2, with the Nb−H−B bridge being cleaved at the H−B site.
Overview of NASA GRC Stirling Technology Development (2003)

The Stirling Radioisotope Generator (SRG) is currently being developed by Lockheed Martin Astronautics (LMA) under contract to the Depar1ment of Energy (DOE). The generator will be a high efficiency electric power source for NASA Space Science missions with the capability to operate in the vacuum of deep space or in an atmosphere such as on the surface of Mars. High system efficiency is obtained through the use of free-piston Stirling power conversion technology. Power output of the generator will be greater than 100 watts at the beginning of life with the decline in power being largely due to the decay of the plutonium heat source. In suppOl1 of the DOE SRG project, the NASA Glenn Research Center (GRC) has established a near-term technology effort to provide some of the critical data to ensure a successful transition to flight for what will be the first dynamic power system used in space. Initially, a limited number of technical areas were selected for the GRC effort, however this is now being expanded to more thoroughly cover a range of technical issues. The tasks include in-house testing of Stirling convertors and controllers, materials evaluation and heater head life assessment, structural dynamics, electromagnetic interference, organics evaluation, and reliability analysis. Most of these high-level tasks have several subtasks within. There is also an advanced technology effort that is complementary near-term technology effort. Many of the tests make use of the 55-We Technology Demonstration Convel10r (TDC). There have been multiple controller tests to support the LMA flight controller design effort. Preparation is continuing for a thermal/vacuum system demonstration. A pair of flight prototype TDC's have recently been placed on an extended test with unattended, continuous operation. Heater head life assessment efforts continue, with the material data being refined and the analysis moving toward the system perspective. Long-term magnet aging tests are continuing to characterize any possible aging in the strength or demagnetization resistance of the permanent magnets used in the linear alternator. In a parallel effort, higher performance magnets are also being evaluated. A reliability effort is being initiated that will help to guide the development activities with an increased focus on the necessary components and subsystems. Some other disciplines that are active in the GRC technology effort include structural dynamics, linear alternator analysis, EMI/EMC, controls, and mechanical design evaluation. This paper will provide an overview of some of the GRC technical efforts, including the current status, and a description of future efforts.
Adversarial Texture Optimization from RGB-D Scans (2020)

Realistic color texture generation is an important step in RGB-D surface reconstruction, but remains challenging in practice due to inaccuracies in reconstructed geometry, misaligned camera poses, and view-dependent imaging artifacts. In this work, we present a novel approach for color texture generation using a conditional adversarial loss obtained from weakly-supervised views. Specifically, we propose an approach to produce photorealistic textures for approximate surfaces, even from misaligned images, by learning an objective function that is robust to these errors. The key idea of our approach is to learn a patch-based conditional discriminator which guides the texture optimization to be tolerant to misalignments. Our discriminator takes a synthesized view and a real image, and evaluates whether the synthesized one is realistic, under a broadened definition of realism. We train the discriminator by providing as `real' examples pairs of input views and their misaligned versions -- so that the learned adversarial loss will tolerate errors from the scans. Experiments on synthetic and real data under quantitative or qualitative evaluation demonstrate the advantage of our approach in comparison to state of the art. Our code is publicly available with video demonstration.
Vesicle aggregation in model systems of supersaturated bile: relation to crystal nucleation and lipid composition of the vesicular phase. (1987)

The presence of small vesicles composed of phospholipid and cholesterol has recently been demonstrated in super-saturated model and in dilute native human biles by several groups using differing methods. Among compositional factors shown to favor spontaneous vesicle formation and prolong the cholesterol monohydrate nucleation time in model bile systems are dilution, a raised cholesterol saturation index (CSI), and a low bile salt/phospholipid ratio. Time-lapse video-enhanced microscopy of a series of model bile systems representing systematically designed variations in the above factors revealed strong evidence for an essential linkage between antecedent vesicle aggregation and subsequent crystal nucleation. Stability of vesicles was inversely related to their degree of cholesterol saturation, i.e., the greater the degree of vesicular cholesterol saturation, the less their stability (metastability). Instability of vesicles was reflected by their early aggregation followed by rapid cholesterol crystal nucleation. The lowest degree of vesicular cholesterol saturation was found in dilute systems which also exhibited the greatest metastability despite a high degree of cholesterol solubility (raised CSI). Conversely, the more concentrated and least metastable systems exhibited both rapid vesicle aggregation and rapid onset of crystal nucleation. These systems, while influenced by the other compositional factors, were found to have a high degree of vesicular cholesterol saturation, i.e., cholesterol/phospholipid molar ratio = 2.0. An additional finding was the extreme variability in the proportionate distribution of total solution cholesterol distributed to the vesicular phase, i.e., from zero to as high as 37%. Higher solute concentration, raised bile salt/lecithin ratio, and raised CSI were interactive and almost equally capable of increasing the proportionate amount of cholesterol in the vesicular phase. In conclusion, lipid compositional differences in model bile systems drastically affect the cholesterol saturation of spontaneously formed phospholipid-cholesterol vesicles. This effect, in turn, exerts a potent influence upon the metastability of vesicles, subsequently affecting the cholesterol crystal nucleation time.