gebhart/patrepeval huggingface dataset:
Assessment of modern spectral analysis methods to improve wavenumber resolution of<i>F‐K</i>spectra (1987)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1987Assessment of modern spectral analysis methods to improve wavenumber resolution of F‐K spectraAuthors: T. E. ShirleyS. J. LasterR. A. MeekT. E. ShirleyMobil Research & Development Corp., S. J. LasterMobil Research & Development Corp., and R. A. MeekSouthern Methodist Universityhttps://doi.org/10.1190/1.1892035 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1892035FiguresReferencesRelatedDetailsCited byNew maximum entropy spectrum using uncertain eigenstructure constraintsIEEE Transactions on Aerospace and Electronic Systems, Vol. 28, No. 1Spectral and sensor array analysis using maximum entropy with new eigenstructure constraints SEG Technical Program Expanded Abstracts 1987ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1987 Pages: 923 publication data© 1987 Copyright © 1987 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 07 Mar 2005 CITATION INFORMATION T. E. Shirley, S. J. Laster, and R. A. Meek, (1987), "Assessment of modern spectral analysis methods to improve wavenumber resolution of F‐K spectra," SEG Technical Program Expanded Abstracts : 607-610. https://doi.org/10.1190/1.1892035 Plain-Language Summary PDF DownloadLoading ...
Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment (2016)

Tuberculosis (TB), a disease caused by the human pathogen Mycobacterium tuberculosis, recently joined HIV/AIDS on the top rank of deadliest infectious diseases. Low patient compliance due to the expensive, long-lasting and multi-drug standard therapies often results in treatment failure and emergence of multi-drug resistant strains. In this scope, antimicrobial peptides (AMPs) arise as promising candidates for TB treatment. Here we describe the ability of the exogenous AMP LLKKK18 to efficiently kill mycobacteria. The peptide's potential was boosted by loading into self-assembling Hyaluronic Acid (HA) nanogels. These provide increased stability, reduced cytotoxicity and degradability, while potentiating peptide targeting to main sites of infection. The nanogels were effectively internalized by macrophages and the peptide presence and co-localization with mycobacteria within host cells was confirmed. This resulted in a significant reduction of the mycobacterial load in macrophages infected in vitro with the opportunistic M. avium or the pathogenic M. tuberculosis, an effect accompanied by lowered pro-inflammatory cytokine levels (IL-6 and TNF-α). Remarkably, intra-tracheal administration of peptide-loaded nanogels significantly reduced infection levels in mice infected with M. avium or M. tuberculosis, after just 5 or 10 every other day administrations. Considering the reported low probability of resistance acquisition, these findings suggest a great potential of LLKKK18-loaded nanogels for TB therapeutics.
Active Video Games for Youth: A Systematic Review (2011)

AVGs are capable of generating EE in youth to attain PA guidelines. Few studies have assessed sustainability of AVG play, which appears to diminish after a short period of time for most players. Better-quality future research must address how AVG play could be maintained over longer periods of time.
Primary gamma delta cell clones can be defined phenotypically and functionally as Th1/Th2 cells and illustrate the association of CD4 with Th2 differentiation. (1998)

The division of CD4+ alpha beta T cells into Th1 and Th2 subsets has become an established and important paradigm. The respective activities of these subsets appear to have profound effects on the course of infectious and autoimmune diseases. It is believed that specific programs of differentiation induce the commitment of an uncommitted Th0 precursor cell to Th1 or Th2. A component of these programs is hypothesized to be the nature of MHC-peptide antigen presentation to the alpha beta T cell. It has heretofore remained uncertain whether a Th1/Th2 classification likewise defines, at the clonal level, gamma delta T cells. Such cells do not, as a general rule, express either CD4 or CD8 alpha beta, and they do not commonly recognize peptide-MHC. In this report, gamma delta cell clones are described that conform strikingly to the Th1/Th2 classification, both by cytokine expression and by functional activities of the clones in vitro and in vivo. Provocatively, both the gamma delta cell clones and primary gamma delta cells in vivo showed a strong association of the Th2 phenotype with CD4 expression. These results are discussed with regard to the immunoregulatory role that is increasingly emerging for gamma delta cells.
Glioblastoma Behaviors in Three-Dimensional Collagen-Hyaluronan Composite Hydrogels (2013)

Glioblastoma multiforme (GBM) tumors, which arise from glia in the central nervous system (CNS), are one of the most deadly forms of human cancer with a median survival time of ∼1 year. Their high infiltrative capacity makes them extremely difficult to treat, and even with aggressive multimodal clinical therapies, outcomes are dismal. To improve understanding of cell migration in these tumors, three-dimensional (3D) multicomponent composite hydrogels consisting of collagen and hyaluronic acid, or hyaluronan (HA), were developed. Collagen is a component of blood vessels known to be associated with GBM migration; whereas, HA is one of the major components of the native brain extracellular matrix (ECM). We characterized hydrogel microstructural features and utilized these materials to investigate patient tumor-derived, single cell morphology, spreading, and migration in 3D culture. GBM morphology was influenced by collagen type with cells adopting a rounded morphology in collagen-IV versus a spindle-shaped morphology in collagen-I/III. GBM spreading and migration were inversely dependent on HA concentration; with higher concentrations promoting little or no migration. Further, noncancerous astrocytes primarily displayed rounded morphologies at lower concentrations of HA; in contrast to the spindle-shaped (spread) morphologies of GBMs. These results suggest that GBM behaviors are sensitive to ECM mimetic materials in 3D and that these composite hydrogels could be used to develop 3D brain mimetic models for studying migration processes.
Shape optimization of piezoelectric sensors dealing with spill-over instability (2001)

This paper deals with the recurrent problem of spill-over that induces instability when the control strategy is based on uncollocated transducers. We first introduce the concept of modal control and the need to limit controllability and observability to a finite set of modes in order to avoid residual coupling effects which is the source of spill-over. Next, we establish the typical form of controllability and observability gramians when the distributed system is discretized on its modal components. An adequate norm is also introduced to optimize these operators. Finally, we show the obvious advantage of optimizing the piezoelectric density of sensors in order to achieve efficient control. An example is treated and shows some typical results obtained by our method.
Lithium perturbation and <i>goosecoid</i> expression identify a dorsal specification pathway in the pregastrula zebrafish (1993)

The zebrafish dorsoventral axis can first be distinguished at gastrulation, upon formation of the embryonic shield, the site of the organizer. We have asked whether the shield is specified before gastrulation. First, we show that brief exposure of premidblastula embryos to lithium, which is known to shut down the phospho-inositol signaling pathway, produces excessive shield formation and extreme hyper-dorsal development. Second, we show that the zebrafish goosecoid homeobox gene is activated at or just after the midblastula in a localized domain of cells that subsequently populate the most anterior region of the incipient shield and axial hypoblast, goosecoid expression is elevated and radialized by early lithium treatment, suggesting that goosecoid plays a role in establishing the organizer and shield. Our results demonstrate that the zebrafish dorsal axis is signaled by a pathway initiated in the cleavage-stage embryo. Furthermore, they provide novel insights into anterior morphogenesis.
Characterization of the <i>Saccharomyces cerevisiae ARG7</i> Gene Encoding Ornithine Acetyltransferase, An Enzyme also Endowed with Acetylglutamate Synthase Activity (1997)

We have cloned by functional complementation and characterized the yeast ARG7 gene encoding mitochondrial ornithine acetyltransferase, the enzyme catalyzing the fifth step in arginine biosynthesis. While forming ornithine, this enzyme regenerates acetylglutamate, also produced in the first step by the ARG2-encoded acetylglutamate synthase. Interestingly, total deletion of the genomic ARG7 ORF resulted in an arginine-leaky phenotype, indicating that yeast cells possess an alternative route for generating ornithine from acetylornithine. Yeast ornithine acetyltransferase has been purified and characterized previously as a heterodimer of two subunits proposed to derive from a single precursor protein [Liu, Y-S., Van Heeswijck R., Hoj, P. & Hoogenraad, N. (1995) Eur. J. Biochem. 228, 291-296]; those authors further suggested that the internal processing of Arg7p, which is a mitochondrial enzyme, might occur in the matrix, while the leader peptide would be of the non-cleavable-type. The characterization of the gene (a) establishes that Arg7p is indeed encoded by a single gene, (b) demonstrates the existence of a cleaved mitochondrial prepeptide of eight residues, and (c) shows that the predicted internal processing site is unlike the mitochondrial proteolytic peptidase target sequence. Yeast Arg7p shares between 32-43% identity in pairwise comparisons with the ten analogous bacterial ArgJ enzymes characterized. Among these evolutionarily related enzymes, some but not all appear bifunctional, being able to produce acetylglutamate not only from acetylornithine but also from acetyl-CoA, thus catalyzing the same reaction as the apparently unrelated acetylglutamate synthase. We have addressed the question of the bifunctionality of the eucaryotic enzyme, showing that overexpressed ARG7 can complement yeast arg2 and Escherichia coli argA mutations (affecting acetylglutamate synthase). Furthermore, Arg7p-linked acetylglutamate synthase activity was measurable in an assay. The yeast enzyme is thus clearly, albeit modestly, bifunctional. As with several bacterial ornithine acetyltransferases, the activity of Arg7p was practically insensitive to arginine but strongly inhibited by ornithine, which behaved as a competitive inhibitor.
Ad Hoc Federation of Networks (FedNets) - Mechanisms and Requirements (2007)

We have been witnessing developments of many innovative applications in the field of ad hoc wireless networks as well as many projects in the area of user-centric, context aware and ambient assisted networks. This paper introduces a novel framework called FedNets that bridges user centric networks to form an ad hoc federation to achieve group cooperation. Our preliminary study of all the mechanisms, requirements and potential techniques that need to be addressed in this regard is presented. We describe a roadmap towards a fully networked cooperative interaction. We believe that this paper will serve as the basis for our next stages of development, as well as for other similar works in the field of wireless ad hoc networks.
Activation of p-Type GaN with Irradiation of the Second Harmonics of a Q-Switched Nd : YAG Laser (2001)

Efficient activation of Mg acceptors for obtaining a high hole concentration is a challenging topic. In this paper, we report the results of Mg acceptor activation in GaN with irradiation of the second-harmonic photons (532 nm in wavelength) of a Q-switched Nd:YAG laser. This laser was used to irradiate two Mg-doped GaN samples of different doping concentrations. With doping concentration of 1.2 × 1018 cm—3, a hole concentration of 2.66 × 1017 cm—3 was obtained after laser-induced activation. The average temperature of samples during laser irradiation was around 30 °C. Hence, it was speculated that the irradiation process was very unlikely to be thermal annealing. PL measurements revealed that laser-induced activation could ionize not only the shallow but also the deep donors.
The Three‐Component Reaction between Isatin, α‐Amino Acids, and Dipolarophiles (2004)

Abstract 3‐Spiro[pyrrolidino‐oxindoles] were prepared in high yields from a three‐component reaction between isatin, an α‐amino acid, and a dipolarophile. Both N ‐substituted and N ‐unsubstituted α‐amino acids were used as the amine component. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
A pathogen‐induced gene of barley encodes a protein showing high similarity to a protein kinase regulator. (1992)

Summary A full length cDNA of a barley leaf messenger, found to increase in amount during infection attempts by the powdery mildew fungus (Erysiphe graminis), is characterized. The messenger encodes a polypeptide of 261 amino acid residues with a calculated mass of 29.2 kDa and a pI of 4.6. Sequence comparisons as well as serological studies demonstrate that the encoded protein is closely related to a family of mammalian proteins believed to have functions associated with the multifunctional Ca(2+)‐dependent protein kinases.
THE PREPARATION OF SOME DIHYDRO KETONES IN THE MORPHINE SERIES BY OPPENAUER OXIDATION (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE PREPARATION OF SOME DIHYDRO KETONES IN THE MORPHINE SERIES BY OPPENAUER OXIDATIONHENRY RAPOPORT, ROBERT NAUMANN, EUGENE R. BISSELL, and ROBERT M. BONNERCite this: J. Org. Chem. 1950, 15, 5, 1103–1107Publication Date (Print):September 1, 1950Publication History Published online1 May 2002Published inissue 1 September 1950https://pubs.acs.org/doi/10.1021/jo01151a029https://doi.org/10.1021/jo01151a029research-articleACS PublicationsRequest reuse permissionsArticle Views662Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Direct observation of inversely polarized frozen nanodomains in fatigued ferroelectric memory capacitors (2003)

The direct observation of blocked polarization domains at the electrode–ferroelectric interface of electrically fatigued ferroelectric films is reported. Blocked nanodomains are believed to be the origin of polarization fatigue in ferroelectric nonvolatile memories but have not been directly observed so far due to the required upper metal electrode which impedes the direct access to the surface of the ferroelectric film. This problem has been solved by using low temperature melting metal as removable top electrode. After fatigue and subsequent top electrode removal it was possible to observe the polarization state of the fatigued capacitor and its depth profile by means of detection of the local piezoelectric activity with a conductive atomic force microscope tip. Blocked polarization domains with opposite polarization compared to the film body could be directly observed at the upper ferroelectrics surface.
Autoantibody Determination in the Diagnosis of Systemic Lupus Erythematosus (2006)

Systemic lupus erythematosus (SLE) is an autoimmune disease that usually develops in young women aged 18-50 years and is characterized by the presence of autoantibodies. Diagnosis is difficult as SLE is a great imitator of other diseases. When SLE is suspected clinically in a patient (involvement of two or more organ systems), an initial laboratory evaluation would be antinuclear antibody (ANA) testing. If ANA is negative, SLE is unlikely and results positive at less than 1:40 strongly argue against SLE. Other explanations for organ system involvement should be pursued. Results positive at greater than 1:40 may merit further evaluation for SLE and at times referral to a rheumatologist for a full SLE evaluation. While the American College of Rheumatology classification criteria for SLE are primarily a tool for research, they may be useful clinically, in that those patients fulfilling four or more criteria are highly likely to have SLE.
Natural Deep Eutectic Solvents for Simultaneous Extraction of Multi-Bioactive Components from Jinqi Jiangtang Preparations (2019)

Natural deep eutectic solvents (NADESs), composed of natural primary metabolites, are now widely used as green and sustainable extraction solvents of bioactive components. In the present study, various NADESs were prepared to extract multi-components from different preparations of an herbal formula (Chinese name: Jinqi Jiangtang, JQJT) using ultrasound-assisted extraction (UAE). Results showed that most prepared NADESs provided more effective extraction of phenolic acids and alkaloids from JQJT preparations than conventional solvents. Among the tested NADESs, the solvent formed by choline chloride and laevulinic acid was selected to optimize the operational parameters using response surface methodology. The optimized extraction method was successfully applied to extract six major components in four commercial JQJT products, and quantification analysis was performed by the validated high-performance liquid chromatography with ultraviolet detection (HPLC-UV) method. The quantitative results indicated that preparations from different manufacturers showed different chemical profiles. In conclusion, NADESs-based UAE shows considerable potential as an efficient and green method for extraction of multi-bioactive components from commercial herbal preparations.
A Novel Phosphate Chemosensor Utilizing Anion-Induced Fluorescence Change (2002)

[structure: see text] The neutral receptor N,N'-bis[3,5-di[(1-pyrenylmethyl)carbamoyl]benzyl] pyridine-2,6-dicarbamide (2) provides a pseudo-tetrahedron cleft and multiple hydrogen bondings to form a 1:1 complex with phosphate ion in a highly selective manner, by comparison with other anions (F(-), Cl(-), Br(-), SCN(-), AcO(-), NO(3)(-), ClO(4)(-), and HSO(4)(-)). The binding strength can be inferred from the emission intensity ratio of the pyrene monomer (lambda(max) 377 nm) to the excimer (lambda(max) 477 nm). Fluorescence titration, X-ray analysis, and NMR studies support a proposed complexation model.
Out‐of body experiences: Cell‐free cell death (1995)

Apoptosis (programmed cell death) is an evolutionarily conserved cellular process, important for development and homeostasis. Most apoptotic cells share a common set of morphological and physiological characteristics that distinguish them from necrotic deaths. While genetic studies have indicated that these characteristic changes result from the activation of an endogenous 'suicide program', little is known about the nature of this program and the molecular events underlying these changes. Two recent papers describing cell-free extracts that reproduce several of the characteristic changes observed in apoptotic cells promise to make these phenomena accessible to biochemical analysis.
Implicit visibility and antiradiance for interactive global illumination (2007)

We reformulate the rendering equation to alleviate the need for explicit visibility computation, thus enabling interactive global illumination on graphics hardware. This is achieved by treating visibility implicitly and propagating an additional quantity, called antiradiance , to compensate for light transmitted extraneously. Our new algorithm shifts visibility computation to simple local iterations by maintaining additional directional antiradiance information with samples in the scene. It is easy to parallelize on a GPU. By correctly treating discretization and filtering, we can compute indirect illumination in scenes with dynamic objects much faster than traditional methods. Our results show interactive update of indirect illumination with moving characters and lights.
Prosthetic Management of a Nasal Septal Defect using a Custom Made Unilateral Intranasal Stent: A Case Report (2016)

Various etiologies including congenital malformations, infections, trauma, iatrogenic causes or complications of systemic diseases can result in perforation of the nasal septum. The common symptoms associated with such defects include difficulty in breathing, nasal twang in voice, rhinorrhea, etc. Obturation can be achieved by insertion of a unilateral nasal stent. An attempt has been made in the present report to address the prosthetic management of pateint having nasal septum perforation utilizing a unilateral, custom made heat cured acrylic stent and the details of the technique are presented.
Memory Observed: Remembering in Natural Contexts (1982)

PART I: THE ARGUMENT PART II: SPECIAL OCCASIONS PART III: EVERYDAY EXPERIENCES PART IV: UNDER OATH PART V: EARLY CHILDHOOD PART VI: TRAUMA: REAL AND IMAGINED PART VII: PERFORMANCES PART VIII: SPECIAL PEOPLE
Effects of the radio-frequency sputtering power of an MgO tunneling barrier on the tunneling magneto-resistance ratio for Co<sub>2</sub>Fe<sub>6</sub>B<sub>2</sub>/MgO-based perpendicular-magnetic tunnel junctions (2015)

For Co<sub>2</sub>Fe<sub>6</sub>B<sub>2</sub>–MgO based p-MTJ spin valves with [Co/Pt]<sub>n</sub>–SyAF layers <italic>ex situ</italic> annealed at 350 °C and 30 kOe for 30 min, the tunneling magneto-resistance (TMR) ratio strongly depended on the radio-frequency (RF) sputtering power in a 0.65–1.15 nm thick MgO tunneling barrier, achieving a TMR ratio of 168% at 300 W.
Adaptive ping control for track-holding in multistatic active sonar networks (2010)

Distributed multistatic active sonar networks provide an Anti-Submarine Warfare capability against small, quiet, threat submarines in the harsh clutter-saturated littoral and deeper ocean environments. Adaptive ping control techniques provide the potential to significantly increase the multistatic network's performance, by pinging (in an optimum sense) the right source, at the right time, with the right waveform. This paper describes an automatic, adaptive ping control algorithm. It specifically addresses the “trackhold” objective, which is to adapt multistatic sonar operations to maintain and hold one or more target tracks which have been previously initiated (detected). The approach is unique in that it includes both sonar performance modeling and multistatic tracker outputs, in a closed-loop control structure. The paper motivates the approach, describes the algorithm, and shows some validating results. The evaluation utilizes a simple sonar performance model, a ping contact simulator, and a multistatic target tracker. Results are shown for a simple simulated scenario, showing the advantages of this adaptive ping control algorithm compared to using a preplanned, non-adaptive ping transmission schedule.