gebhart/patrepeval huggingface dataset:
Velocity filters for multiple interferences in two-dimensional geophysical data (1991)

A procedure for the velocity filtering of two-dimensional geophysical data is discussed. This procedure involves repeatedly applying multichannel filters to a small number of overlapping subarrays of the input data. The multichannel filters can be chosen so that the resulting velocity filter is capable of suppressing multiple interferences traveling at different velocities. The two-dimensional frequency-wavenumber expression of the velocity filter is derived. With this expression, it becomes possible to implement the filter using two-dimensional fast Fourier transform (FFT) techniques. Two examples which illustrate the performance of the derived filters are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
High-Performance Flexible Perovskite Solar Cells on Ultrathin Glass: Implications of the TCO (2017)

For halide perovskite solar cells (PSCs) to fulfill their vast potential for combining low-cost, high efficiency, and high throughput production they must be scaled using a truly transformative method, such as roll-to-roll processing. Bringing this reality closer to fruition, the present work demonstrates flexible perovskite solar cells with 18.1% power conversion efficiency on flexible Willow Glass substrates. We highlight the importance of the transparent conductive oxide (TCO) layers on device performance by studying various TCOs. While tin-doped indium oxide (ITO) and indium zinc oxide (IZO) based PSC devices demonstrate high photovoltaic performances, aluminum-doped zinc oxide (AZO) based devices underperformed in all device parameters. Analysis of X-ray photoemission spectroscopy data shows that the stoichiometry of the perovskite film surface changes dramatically when it is fabricated on AZO, demonstrating the importance of the substrate in perovskite film formation.
Simulation of protein conformational freedom as a function of pH: constant‐pH molecular dynamics using implicit titration (1997)

Solution pH is a determinant parameter on protein function and stability, and its inclusion in molecular dynamics simulations is attractive for studies at the molecular level. Current molecular dynamics simulations can consider pH only in a very limited way, through a somewhat arbitrary choice of a set of fixed charges on the titrable sites. Conversely, continuum electrostatic methods that explicitly treat pH effects assume a single protein conformation whose choice is not clearly defined. In this paper we describe a general method that combines both titration and conformational freedom. The method is based on a potential of mean force for implicit titration and combines both usual molecular dynamics and pH-dependent calculations based on continuum methods. A simple implementation of the method, using a mean field approximation, is presented and applied to the bovine pancreatic trypsin inhibitor. We believe that this constant-pH molecular dynamics method, by correctly sampling both charges and conformation, can become a valuable help in the understanding of the dependence of protein function and stability on pH. © 1997 Wiley-Liss Inc.
α<sub>1</sub>‐Adrenoceptor Blocking Activity of Some Ring‐open Analogues of Prazosin (1994)

Synthesis and structural characterization of some ring-open analogues of Prazosin containing either the guanidine substructure or urea-equivalent groups are described. The opening of the pyrimidine ring in Prazosin is very important as far as the affinity for alpha 1-adrenoceptor is concerned. The pA2 values of the ring-open derivatives are 10(4)-10(5) fold lower than that of the parent. It is probable that the affinity decrease principally reflects a negative influence of the conformational factors in the interaction with the alpha 1-receptor. The derivative 5 containing the guanidine moiety, charged at physiological pH, is as active as the other derivatives containing the uncharged urea-equivalent groups. This behaviour indicates, in this class of compounds, the importance of H-bonding interactions with the receptor. When in the ring-open models the ethanediamino substructure is substituted for the piperazine ring additional decrease in activity occurs.
A New Permanent Exteriorized Epidural Catheter for Narcotic Self-Administration to Control Cancer Pain (1987)

The lack of an available exteriorized permanent epidural catheter led to the application of the Broviac catheter technology to the development of an epidural catheter. The resulting three-piece silicone-rubber catheter system allows specific spinal-level location of the catheter tip from a lumbar entry site, and exteriorization for ease of self-administration. Fifty-five cancer patients with metastatic disease and intractable pain received 58 catheters. No catheter infections were found during 3891 catheter-days of use, and only 18 minor side effects were noted, with no respiratory depression observed. Hospitalizations for pain control was decreased by 90% after catheter placement. Therefore, the authors recommend early placement of this silicone-rubber epidural catheter to control pain unrelieved by oral analgesics.
Protecting the Internet's Flow (2005)

The ACCC chief argues that the Internet brings a new generation of challenges to Australia's competition regulators and that the ACCC will continue to closely scrutinise the acquisition of exclusive rights to content to ensure that no carrier is able to use them to create a major barrier to entry into infrastructure markets. This article is an extract from Graeme Samuel's May 2005 address to CEDA in Melbourne, 'Cartels, Media and Telecommunications'.
A soft decision viterbi decoding method using received carrier level in fading channel (1990)

Abstract Transmission channels in mobile communication are extremely unstable due to the effect of multipath fading. Therefore the realization of high‐reliability communication necessitates the introduction of error control in the form of error‐correction coding. This paper considers the decoding of error‐correcting codes that are adapted to digital mobile communication operating under Rayleigh fading conditions. A soft decision Viterbi decoding using the received carrier level is studied for the case of convolutional codes. This soft decision method is based on the level of the received carrier by adaptively determining the metric used in the decoding. In this way a metric is obtained for digital mobile communication. This paper also presents an estimation method using error exponent which provides effective means to realize such a soft decision method. If the channel can be considered memoryless due for example to interleaving, then this method provides an easy way to estimate: (1) the figure of merit for quantizing thresholds, and (2) the gains of the soft decision. First, it is shown that using this kind of estimation in the case of channels which can be considered sufficiently memoryless due to interleaving, extremely large gain is obtained by the soft decision method discussed in this paper. Next, simulations are performed and the efficiency of the estimation method is demonstrated. Finally, the bit error rate characteristics are shown for the case when the channel is not made sufficiently memoryless by interleaving.
Hyperglycemia Does Not Modify the Pupillary Effects of [unk] and <i>k</i> Opiate Agonists in Mice (1989)

The effects of mu and kappa opiate agonists were assessed on the pupillary size in normoglycemic and hyperglycemic conditions in mice. The mu agonists used were, morphine (10, 30 and 100 mg/kg), fentanyl (50, 100 and 150 micrograms/kg) and sufentanil (5, 10 and 20 micrograms/kg). The highly selective kappa opiate agonists used were, U-50488H and U-69593 (30 mg/kg). Chronic hyperglycemia was induced by streptozotocin injection (200 mg/kg i.p) 7-8 days before the experiment. Acute hyperglycemia was induced by intraperitoneal glucose (5 g/kg i.p) injection at the time of subcutaneous injection of opiates. In the normoglycemic mice, the mu agonists produced significant mydriasis (P less than 0.05), while kappa agonists had no effect on the pupil. However, both acute and chronic hyperglycemic condition did not affect the mydriatic ratio of the mu opiate agonists. These results indicate that mu opiate receptors induce mydriasis in mice and suggest that the hyperglycemia is not the mechanism involved in the opiate induced mydriasis in mice. With the dose of kappa agonists used, the involvement of kappa receptors in the pupillary effects in mice were not clear. These results support the hypothesis that hyperglycemia is not the primary mechanism for the altered sensitivity of opiates in the animal models of diabetes.
Update to new oncology medical home standards (2021)

The American Society of Clinical Oncology (ASCO) and the Community Oncology Alliance (COA) have jointly released new Oncology Medical Home (OMH) guidelines to standardize the definition of high-quality oncology care. The specific domains detailed in the new standards demonstrate a shared governance among all stakeholders rather than only among practices, institutions, and high-level practitioners. Informed decision making is encouraged to include providers at every level, with the primary focus remaining on all patients and caregivers , regardless of whether they live close to large institutions or in affluent communities. The comprehensive standards serve as a reference to guide all stakeholders in transitioning care toward high-quality, value-based, equitable standards throughout the care continuum.
Recurrent Reinforcement Learning: A Hybrid Approach (2015)

Successful applications of reinforcement learning in real-world problems often require dealing with partially observable states. It is in general very challenging to construct and infer hidden states as they often depend on the agent's entire interaction history and may require substantial domain knowledge. In this work, we investigate a deep-learning approach to learning the representation of states in partially observable tasks, with minimal prior knowledge of the domain. In particular, we propose a new family of hybrid models that combines the strength of both supervised learning (SL) and reinforcement learning (RL), trained in a joint fashion: The SL component can be a recurrent neural networks (RNN) or its long short-term memory (LSTM) version, which is equipped with the desired property of being able to capture long-term dependency on history, thus providing an effective way of learning the representation of hidden states. The RL component is a deep Q-network (DQN) that learns to optimize the control for maximizing long-term rewards. Extensive experiments in a direct mailing campaign problem demonstrate the effectiveness and advantages of the proposed approach, which performs the best among a set of previous state-of-the-art methods.
Intelligent heart disease prediction system using data mining techniques (2008)

The healthcare industry collects huge amounts of healthcare data which, unfortunately, are not ";mined"; to discover hidden information for effective decision making. Discovery of hidden patterns and relationships often goes unexploited. Advanced data mining techniques can help remedy this situation. This research has developed a prototype Intelligent Heart Disease Prediction System (IHDPS) using data mining techniques, namely, Decision Trees, Naive Bayes and Neural Network. Results show that each technique has its unique strength in realizing the objectives of the defined mining goals. IHDPS can answer complex ";what if"; queries which traditional decision support systems cannot. Using medical profiles such as age, sex, blood pressure and blood sugar it can predict the likelihood of patients getting a heart disease. It enables significant knowledge, e.g. patterns, relationships between medical factors related to heart disease, to be established. IHDPS is Web-based, user-friendly, scalable, reliable and expandable. It is implemented on the .NET platform.
Wavelet-based Color Image Watermarking using Adaptive Entropy Casting (2006)

An adaptive robust image watermarking technique for color image authentication is proposed. In the proposed approach, the Y channel of a Yuv color host image and a concatenated RGB color-image watermark are decomposed into wavelet coefficients. The contextual entropies of the host wavelet coefficients are computed by a log-sum entropy measurement. Then the watermark wavelet coefficients are embedded into the host wavelet coefficients with larger entropy in the corresponding wavelet subbands. An adaptive casting strategy is utilized to embed the watermark coefficients for fully controlling the imperceptibility of watermarked images and the robustness of watermarks. The experimental results show that the proposed approach provides extra robustness against JPEG-compression and image-processing attacks; moreover, the proposed approach has no need of the original host image to extract watermarks
Hierarchical IDEAL: Fast, robust, and multiresolution separation of multiple chemical species from multiple echo times (2012)

We describe a generalized version of hierarchical IDEAL that can flexibly handle arbitrary chemical species at arbitrary echo times. The proposed work is fast and robust, and it has three key features: (1) multiresolution approach, which allows the method to handle images with disjoint regions, makes it less susceptible to local optima, and reduces the ambiguity of the separation; (2) direct phase estimation, which bypasses the phase wrapping issue, and (3) efficient algebraic formulation, which enables fast calculation and insensitivity to spatially varying phase across the image, from sources such as partial echo acquisition, receiver coils, motion, and flow. Representative results at 1.5 T and 3 T are presented from human ankle, wrist, and a water/oil/silicone phantom.
Computing the discrepancy with applications to supersampling patterns (1996)

Patterns used for supersampling in graphics have been analyzed from statistical and signal-processing viewpoints. We present an analysis based on a type of isotropic discrepancy—how good patterns are at estimating the area in a region of defined type. We present algorithms for computing discrepancy relative to regions that are defined by rectangles, halfplanes, and higher-dimensional figures. Experimental evidence shows that popular supersampling patterns have discrepancies with better asymptotic behavior than random sampling, which is not inconsistent with theoretical bounds on discrepancy.
Liquid-phase epitaxy processing of RBa<sub>2</sub>Cu<sub>3</sub>O<sub>7−δ</sub> (2000)

The study of processing by liquid-phase epitaxy (LPE) is promising because the LPE process can provide rapid and thick film formation of RBa2 Cu3 O7- (RBCO). The growth rate can reach 10 µm min-1and films of more than 5 µm in thickness formed by the LPE process show a high critical current density of about 1 MA cm-2 . To apply this process widely, a decrease of the processing temperature is required because it gives rise to a reaction between the solution and many of the substrate materials. Film formation on yttria-stabilized ZrO2and silver substrates, which are more reactive than other materials such as MgO or SrTiO3 , has been achieved by decreasing the temperature to below 920 °C, with the addition of BaF2in the solution. This paper describes processing by LPE for forming RBCO films and efforts for practical application towards coated conductors and RF electronic devices.
Synthesis, opioid receptor binding profile, and antinociceptive activity of 1-azaspiro[4.5]decan-10-yl amides (1989)

A series of azaspiro[4.5]decanyl amides were prepared by a novel cyclization route and examined for opiate receptor binding and antinociceptive activity. Selected tertiary amides in this series showed potent selective mu-receptor binding and antinociceptive activity, in contrast to the less conformationally restricted secondary amides, which showed relatively weak activity. Although structurally similar to the kappa-agonist U-50488H (1), these compounds showed virtually no tendency to bind to the kappa-receptor. An X-ray crystal structure of compound (21) confirms that the spirocyclic amine does not cause distortion away from the chair conformation of the cyclohexane ring. Either this receptor has very specific requirements for the orientation of the two nitrogens of these compounds or this ring system fills a portion of space more readily tolerated by the mu- and delta-receptors.
Lewis Acid Assisted Ring-Closing Metathesis of Chiral Diallylamines:  An Efficient Approach to Enantiopure Pyrrolidine Derivatives (2005)

Lewis acid assisted ring-closing olefin metathesis (RCM) of chiral diallylamines, using the second generation RCM ruthenium-based catalyst, leads to enantiopure pyrrolidine derivatives in 79-93% yields under very mild conditions. The scope of the olefin metathesis has been expanded. [structure: see text]
Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24). (1996)

Plectin, a 500-kDa intermediate filament binding protein, has been proposed to provide mechanical strength to cells and tissues by acting as a cross-linking element of the cytoskeleton. To set the basis for future studies on gene regulation, tissue-specific expression, and pathological conditions involving this protein, we have cloned the human plectin gene, determined its coding sequence, and established its genomic organization. The coding sequence contains 32 exons that extend over 32 kb of the human genome. Most of the introns reside within a region encoding the globular N-terminal domain of the molecule, whereas the entire central rod domain and the entire C-terminal globular domain were found to be encoded by single exons of remarkable length, >3 kb and >6 kb, respectively. Overall, the organization of the human plectin gene was strikingly similar to that of human bullous pemphigoid antigen 1 (BPAG1), confirming that both proteins belong to the same gene family. Comparison of the deduced protein sequences for human and rat plectin revealed that they were 93% identical. By using fluorescence in situ hybridization, we have mapped the plectin gene to the long arm of chromosome 8 within the telomeric region. This gene locus (8q24) has previously been implicated in the human blistering skin disease epidermolysis bullosa simplex Ogna. Detailed knowledge of the structure of the plectin gene and its chromosome localization will aid in the elucidation of whether this or any other pathological conditions are linked to alterations in the plectin gene.
Handling inelastic traffic in wireless sensor networks (2010)

The capabilities of sensor networking devices are increasing at a rapid pace. It is therefore not impractical to assume that future sensing operations will involve real time (inelastic) traffic, such as audio and video surveillance, which have strict bandwidth constraints. This in turn implies that future sensor networks will have to cater for a mix of elastic (having no bandwidth constraint requirements) and inelastic traffic. Current state of the art rate control protocols for wireless sensor networks, are however designed with focus on elastic traffic. In this work, by adapting a recently developed theory of utilityproportional rate control for wired networks to a wireless setting, and combining it with a stochastic optimization framework that results in an elegant queue backpressure-based algorithm, we have designed the first-ever rate control protocol that can efficiently handle a mix of elastic and inelastic traffic in a wireless sensor network. We implement this novel protocol in a real world sensor network stack, the TinyOS-2.x communication stack for IEEE 802.15.4 radios and evaluate the real-world performance of this protocol through comprehensive experiments on 20 and 40-node subnetworks of USC's 94-node Tutornet wireless sensor network testbed.
Effects of Solvent and Ionic Strength on the Electrochemiluminescence of 9,10-Diphenylanthracene (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffects of Solvent and Ionic Strength on the Electrochemiluminescence of 9,10-DiphenylanthraceneKarolyn M. Maness, Joan E. Bartelt, and R. Mark WightmanCite this: J. Phys. Chem. 1994, 98, 15, 3993–3998Publication Date (Print):April 1, 1994Publication History Published online1 May 2002Published inissue 1 April 1994https://pubs.acs.org/doi/10.1021/j100066a015https://doi.org/10.1021/j100066a015research-articleACS PublicationsRequest reuse permissionsArticle Views403Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A novel method for high accuracy sumoylation site prediction from protein sequences (2008)

By using a statistical method, we have developed a new SUMO site prediction method - SUMOpre, which has shown its great accuracy with correlation coefficient, specificity, sensitivity and accuracy.
The Ideal Drug Delivery System: A Look into the Future (1991)

In the very near future, the CFC manufacturers are going to be obliged to stop their production as a result of the "Montreal protocole on substances that deplete the ozone layer". The replacement of these propellants by other fluorinated ones will be possible as soon as their lack of toxicity has been demonstrated. Other substitution substances like haliphatic hydrocarbons (butane, propane) or compressed air generated by the device system itself or the user himself are also under development. The pulverisation can also be obtained by the pressure of a classical propellant onto an aluminum or plastic bag. The dispersion is achieved by means of a regulator which is positioned into the valve. The hand-operated spray pumps with or without compression will also allow the obtention of very small particles though the delivered doses are reduced. However, as few of the new devices have metered valves, they are not yet suitable for pulmonary administration.
In situ detection of cytochrome c adsorption with single walled carbon nanotube deviceElectronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b302681g/ (2003)

We report on the in situ detection of cytochrome c adsorption onto individual SWNT transistors via the changes in the electron transport properties of the transistors.