gebhart/patrepeval huggingface dataset:
Relative Permeabilities From Displacement Experiments With Full Account for Capillary Pressure (1998)

Summary Relative permeabilities are important characteristics of multiphase flow in porous media. Displacement experiments for relative permeabilities are frequently interpreted by the Johnson-BosslerNaumann method neglecting capillary pressure. The experiments are therefore conducted at high flooding rates, which tend to be much higher than those experienced during reservoir exploitation. Another disadvantage is that the relative permeabilities only can be determined for the usually small saturation interval outside the shock. We present a method to interpret displacement experiments with the capillary pressure included, using in-situ measurements of saturations and phase pressures. The experiments can then be run at low flow rates, and relative permeabilities can be determined for all saturations. The method is demonstrated by using simulated input data.
Magnetocaloric effect, thermal conductivity, and magnetostriction of epoxy-bonded La(Fe<sub>0.88</sub>Si<sub>0.12</sub>)<sub>13</sub> hydrides (2017)

Magnetic materials with large magnetocaloric effect are significantly important for magnetic refrigeration. La(Fe0.88Si0.12)13 compounds are one of the promising magnetocaloric materials that have a first order magnetic phase transition. Transition temperature of hydrogenated La(Fe0.88Si0.12)13 increased up to room temperature region while keeping metamagnetic transition properties. From view point of practical usage, bonded composite are very attractive and their properties are important. We made epoxy bonded La(Fe0.88Si0.12)13 hydrides. Magnetocaloric effect was studied by measuring specific heat, magnetization, and temperature change in adiabatic demagnetization. The composite had about 20% smaller entropy change from the hydrogenated La(Fe0.88Si0.12)13 powder in 2 T. Thermal conductivity of the composite was several times smaller than La(Fe,Si)13. The small thermal conductivity was explained due to the small thermal conductivity of epoxy. Thermal conductivity was observed to be insensitive to magnetic field in 2 T. Thermal expansion and magnetostriction of the composite material were measured. The composite expanded about 0.25% when it entered into ferromagnetic phase. Magnetostriction of the composite in ferromagnetic phase was about 0.2% in 5 T and much larger than that in paramagnetic phase. The composite didn't break after about 100 times magnetic field changes in adiabatic demagnetization experiment even though it has magnetostriction.
Ultra-Compact and Low-Loss Polarization Rotator Based on Asymmetric Hybrid Plasmonic Waveguide (2013)

We propose a novel hybrid plasmonic polarization rotator based on mode interference. Operating at the telecommunication wavelength of 1.55 μm, the rotation length is very short (3.2 μm), while the polarization conversion efficiency is as high as 99.5%. The total device insertion loss is only 1.38 dB, much smaller than the common level of plasmonic devices. It also has potential to realize integrated waveplates for various polarization states.
Detection of epstein‐barr virus DNA in formalin‐fixed paraffin‐embedded tissue of nasopharyngeal carcinoma using polymerase chain reaction and in situ hybridization (1991)

The polymerase chain reaction method for amplification of DNA in formalin-fixed, paraffin-embedded tissue sections was used to detect Epstein-Barr virus DNA in nasopharyngeal carcinomas from Japanese patients. Thirty-one cases of nasopharyngeal carcinoma and 8 cases of lymph node metastasis of nasopharyngeal carcinoma were studied. Detection rates of Epstein-Barr virus in various types of nasopharyngeal carcinoma according to the World Health Organization classification were as follows: 10 of 10 undifferentiated carcinomas, 8 of 13 nonkeratinizing carcinomas, and 5 of 7 keratinizing carcinomas. Eight lymph node metastases, for which the primary was positive for Epstein-Barr virus, also contained Epstein-Barr virus DNA. By in situ hybridization using a biotinylated Epstein-Barr virus probe, it was clearly demonstrated that Epstein-Barr virus DNA was localized in the nuclei of the neoplastic cells. The clinical features of nasopharyngeal carcinoma with or without Epstein-Barr virus were not different. These results demonstrate that nasopharyngeal carcinoma in Japanese patients is closely associated with Epstein-Barr virus infection, similar to nasopharyngeal carcinoma of other endemic and nonendemic areas.
Sulfur-Asphalt Dispersions (1941)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSulfur-Asphalt DispersionsIsaac BencowitzCite this: Ind. Eng. Chem. 1941, 33, 9, 1165–1168Publication Date (Print):September 1, 1941Publication History Published online1 May 2002Published inissue 1 September 1941https://pubs.acs.org/doi/10.1021/ie50381a017https://doi.org/10.1021/ie50381a017research-articleACS PublicationsRequest reuse permissionsArticle Views50Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Extending sensor networks into the cloud using amazon web services (2011)

Abstract—Sensor networks provide a method of collecting environmental data for use in a variety of distributed appli-cations. However, to date, limited support has been provided for the development of integrated environmental monitoring and modeling applications. Specifically, environmental dynamism makes it difficult to provide computational resources that are sufficient to deal with changing environmental conditions. This paper argues that the Cloud Computing model is a good fit with the dynamic computational requirements of environmental monitoring and modeling. We demonstrate that Amazon EC2 can meet the dynamic computational needs of environmental applications. We also demonstrate that EC2 can be integrated with existing sensor network technologies to offer an end-to-end environmental monitoring and modeling solution. I.
Polymers by the reaction of <i>bis</i>(pyrylium salts) with diamines: A novel approach to ionene polymers (1988)

Abstract The following reactions of pyrylium salts with amines are described: (1) bis (pyrylium salts) with amines; (2) diamines with pyrylium salts; and (3) bis (pyrylium salts) with diamines. Both (1) and (2) give bis (pyridinium salts) in high yields, and (3) gives the corresponding polymers which are isolated and characterized. This procedure was applied to cationic bis (pyrylium salts) to give cationic dimers and polymers, and further to zwitterionic bis (pyrylium salts) to yield the corresponding zwitterionic dimers and polymers.
Cooperative Control Strategy of Energy Storage System and Microsources for Stabilizing the Microgrid during Islanded Operation (2010)

In this paper, the cooperative control strategy of microsources and the energy storage system (ESS) during islanded operation is presented and evaluated by a simulation and experiment. The ESS handles the frequency and the voltage as a primary control. And then, the secondary control in microgrid management system returns the current power output of the ESS into zero. The test results show that the proposed cooperative control strategy can regulate the frequency and the voltage, and the secondary control action can contribute to improve the control capability.
Acetyl-CoA carboxylase inhibition for the treatment of metabolic syndrome. (2004)

Metabolic syndrome is defined as a clustering of cardiovascular risk factors (abdominal obesity, hyperinsulinemia, atherogenic dyslipidemia, hypertension and hypercoagulability) that together increase the risk of developing coronary heart disease and type 2 diabetes. Inhibition of acetyl-CoA carboxylase (ACC), which results in inhibition of fatty acid synthesis and stimulation of fatty acid oxidation, has the potential to favorably affect a multitude of cardiovascular risk factors associated with metabolic syndrome. ACC exists as two tissue-specific isozymes, ACC1 present in lipogenic tissues (liver and adipose) and ACC2 present in oxidative tissues (liver, heart and skeletal muscle). Studies in both ACC2 knockout mice and animals administered isozyme-nonselective ACC inhibitors have demonstrated the utility of treating metabolic syndrome through this modality. An isozyme-non-selective ACC inhibitor may potentially provide the optimal therapeutic for beneficially affecting metabolic syndrome. However, demonstration of the full potential of isozyme-selective inhibitors, once identified, should reveal advantages and liabilities associated with single isozyme inhibition. While demonstrating clinical efficacy of an ACC inhibitor should be relatively straightforward, the heterogeneity of the patient population and the absence of established guidelines regarding approval endpoints for agents simultaneously affecting multiple aspects of metabolic syndrome will pose developmental challenges for initial market entries.
The appropriate evaluation of the benign prostatic hyperplasia patient (1994)

Benign prostatic hyperplasia (BPH) is a very prevalent disease process in the aging male. It is characterized by symptoms referred to as 'prostatism'. Although it rarely threatens the life of the patient, it does affect the quality of his life; the evaluation of a patient with BPH should therefore focus on a quantitative assessment of the symptoms and the degree to which they bother the patient. The baseline evaluation of patients with BPH should also include medical history, focused physical examination, urinalysis, and assessment of renal function. Other tests, such as prostate-specific antigen measurement, residual urine measurement, uroflowmetry, pressure-flow studies, and imaging of the urinary tract, should be used after their benefits and risks have been weighed. Tests must be examined for their ability to differentiate BPH from other conditions, predict the outcome of therapy, and improve the selection process for certain treatments.
Designing Distributed Applications with XML, ASP, IE5, LDAP and MSMQ (1999)

Neuroimaging facilitates the translation of animal pre-clinical research to human application. The large porcine spinal cord is useful for testing invasive interventions. Ideally, the safety and efficacy of a delayed intervention is tested in pigs that have recovered sufficiently after spinal cord injury (SCI) to allow either deterioration or improvement of function to be detected. We set out to create moderate severity T9 injuries in Yucatan minipigs by conducting a bridging study adapting methods previously developed in infant piglets. The injury severity was varied according to two pneumatic impactor parameters: the piston compression depth into tissue or the velocity. To stratify locomotor recovery, a 10-point scale used in prior piglet studies was redefined through longitudinal observations of spontaneous recovery. Using hindlimb body weight support to discriminate injury severity, we found that end-point recovery was strongly bimodal to either non-weight-bearing plegia with reciprocating leg movements (<5/10) or recovery of weight bearing that improved toward a ceiling effect (≥ 8/10). No intermediate recovery animals were observed at 2 months post-injury. The ability of intra-operative ultrasound and acute magnetic resonance imaging (MRI) to provide immediate predictive feedback regarding tissue and vascular changes following SCI was assessed. There was an inverse association between locomotor outcome and early gray matter hemorrhage on MRI and ultrasound. Epicenter blood flow following contusion predicted recovery or non-recovery of weight-bearing. The depth of the dorsal cerebrospinal fluid space, which varied between animals, influenced injury severity and confounded the results in this fixed-stroke paradigm.
A Novel Human Insulin-Like Growth Factor I Messenger RNA is Expressed in Normal and Tumor Cells (1990)

We have identified and characterized a novel human insulin-like growth factor I (IGF-I) precursor from the transplantable T61 human breast cancer xenograft and from normal liver. The mRNA encoding this precursor contains a 5'-untranslated region that is 83% identical to the corresponding region of a previously described variant rat IGF-I. The nucleotide sequence of the cloned cDNA predicts an IGF-IA protein precursor of 137 amino acids, including a 32 residue signal peptide, 70 amino acid IGF-I, and a 35 residue COOH-terminal extension or E peptide. The exon encoding this variant maps in the genome between IGF-I exons 1 and 2, in a similar location to the homologous rat exon 1a. The rat and human exons 1a are 59% identical over 1443 nucleotides, with DNA sequence conservation occurring in a mosaic pattern. Human IGF-I mRNAs encoding this novel exon are expressed in liver, T61 tumor cells, and in an ovarian carcinoma cell line, NIH OVCAR3. These studies demonstrate that as in the rat, the human IGF-I gene contains six exons that are variably processed into multiple IGF-I mRNAs. The mechanisms responsible for generating different IGF-I mRNAs thus appear to be conserved among mammalian species.
A Novel Impedance Definition of a Parallel Plate Pair for an Intrinsic Via Circuit Model (2010)

Rigorous analysis of via-plate-pair interactions requires the impedance of a plate pair to be defined in terms of radial transmission lines on perfect magnetic conductor (PMC) ports. The plate domain is not a solid plate pair but one with multiple PMC holes where conventional impedance definitions are not suitable. A new impedance definition is proposed where port voltages and currents are expressed in terms of the inward and outward zero-order modes of a radial transmission line. Radial scattering parameters among multiple radial ports are then introduced and the transforms between the radial scattering and impedance matrices are given. An analytical formula for the radial scattering matrix in a circular plate pair is derived using the addition theorems of cylindrical waves. Furthermore, a boundary integral-equation method is developed to calculate the radial scattering matrix for any irregular plate pair. The method is validated by analytical and numerical simulations as well as measurements.
Platoon dispersion and the linking of traffic signals (1976)

A trial and error approach such as is involved in the preparation of a time-and-distance diagram can produce reasonable progression along a major traffic route. Where however it is desired to minimise delay at signal-controlled intersections in a network a more rigorous approach is desirable.
IMMUNOLOGIC STUDIES OF WATER-SOLUBLE HUMAN AMYLOID FIBRILS (1969)

Eight preparations of soluble amyloid and degraded amyloid (DAM) were compared immunologically. Unlike amyloid fibrils, six of eight preparations of DAM proved to be relatively strong immunogens. Antisera to DAM reacted weakly or not at all with normal human serum or extracts of normal tissues, but were specifically reactive with amyloid fibrils or DAM. Comparative studies of DAM'S from eight different subjects showed some degree of cross-reactivity among them, yet demonstrated that they were not identical. Similar conclusions were obtained by quantitative precipitin and complement fixation analyses. Comparison of the amyloid fibrils with the homologous DAM by complement fixation and absorption studies demonstrated the existence in DAM of antigenic determinants that were lacking or inaccessible in the native fibrils. A search for amyloid precursors and antibodies to amyloid in the sera of 12 patients proved unsuccessful.
New Circulin Macrocyclic Polypeptides from <i>Chassalia </i><i>p</i><i>arvifolia</i> (2000)

Four new macrocyclic polypeptides were isolated and identified from an extract of the tropical tree Chassalia parvifolia. Circulins C-F are 29-30 amino acid cyclic peptides in which the entire primary amino acid chain is covalently cyclized via peptide bonds. Their structures were deduced from a combination of FABMS analyses, N-terminal Edman degradation, endoproteinase digestion, and amino acid analyses. All the peptides share a high degree of sequence homology and contain six cysteine residues forming three intramolecular disulfide bridges. Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection with EC(50) values of 50-275 nM.
Multielectrocatalysis by Layer-by-Layer Films Based on Pararosaniline and Vanadium-Substituted Phosphomolybdate (2015)

Hybrid multilayer films based on the two molecular species pararosaniline (PR) and Keggin-type polyoxometalate K5[PMo11VO40)] (PMo11V) were prepared on different substrates using the electrostatic layer-by-layer (LbL) self-assembly method. The film buildup, monitored by electronic spectroscopy, showed a regular stepwise growth, and X-ray photoelectron spectroscopy data confirmed the presence of both molecular components within the LbL films. Scanning electron microscopy images revealed a completely covered surface with a nonuniform distribution of film components, and atomic force microscopy images confirmed a rough surface. The film electrochemical responses and permeability were studied by cyclic voltammetry. Films revealed three Mo-based redox processes (Mo(VI) → Mo(V)) and one V-based redox process (V(V) → V(IV)) in the potential range between 0.8 and -0.4 V vs Ag/AgCl. Studies with the redox probes [Fe(CN)6](3-/4-) and [Ru(NH3)6](3+/2+) showed that the films maintain the permeability even after six bilayers. Furthermore, the {PR/PMo11V}n multilayer films exhibit excellent Mo-based electrocatalytic activity toward reduction of iodate and V-based electrocatalytic activity toward ascorbic acid oxidation, thus acting as a versatile multielectrocatalyst.
Structure-Directing and High-Efficiency Photocatalytic Hydrogen Production by Ag Clusters (2014)

H2 production by water splitting is hindered mainly by the lack of low-cost and efficient photocatalysts. Here we show that sub-nanometric silver clusters can catalyze the anisotropic growth of gold nanostructures by preferential adsorption at certain crystal planes of Au seeds, with the result that the final nanostructure can be tuned via the cluster/seed ratio. Such semiconducting Ag clusters are extremely stable and retain their electronic structure even after adsorption at the tips of Au nanorods, enabling various photocatalytic experiments, such as oxygen evolution from basic solutions. In the absence of electron scavengers, UV irradiation generates photoelectrons, which are stored within the nanorods, increasing their Au Fermi level up to the redox pinning limit at 0 V (RHE), where hydrogen evolution occurs with an estimated high efficiency of 10%. This illustrates the considerable potential of very small zerovalent, nonmetallic clusters as novel atomic-level photocatalysts.
Expression of Fucosyltransferase 8 Is Associated with an Unfavorable Clinical Outcome in Non-Small Cell Lung Cancers (2015)

High expression of FUT8 is associated with an unfavorable clinical outcome in patients with potentially curatively resected NSCLCs, suggesting that FUT8 can be a prognostic factor. The analysis of FUT8 expression and its core fucosylated products may provide new insights for the therapeutic targets of NSCLCs.
The personal touch (2000)

article Free Access Share on The personal touch Author: Dennis Fowler View Profile Authors Info & Claims netWorkerVolume 4Issue 4Dec. 2000 pp 25–29https://doi.org/10.1145/354573.354580Published:01 December 2000Publication History 1citation890DownloadsMetricsTotal Citations1Total Downloads890Last 12 Months21Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteView all FormatsPDF
Lenalidomide: A New Agent for Patients With Relapsed or Refractory Multiple Myeloma (2007)

Lenalidomide is a potent, novel thalidomide analog that has demonstrated promising clinical activity in patients with relapsed or refractory multiple myeloma (MM). It is a lead immunomodulatory drug currently approved by the U.S. Food and Drug Administration. Neutropenia, thrombocytopenia, and thromboembolic events are common adverse effects associated with lenalidomide therapy in patients with MM. Careful monitoring of those known serious adverse effects is essential to prevent life-threatening complications. This article discusses lenalidomide's mechanisms of action, clinical trial results, and the management of common adverse effects in patients with MM.
Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours (2009)

The right keys for tumour locks: Nitroaromatic and heteroaromatic portions are suitably sensitive to hypoxic conditions when used as BAPN masking groups, and the resulting prodrugs (pro-BAPNs) showed good levels of in vitro hypoxia-selective inhibition of lysyl oxidase (LOX) activity and cancer cell invasion.
Quantitative Persulfide Site Identification (qPerS-SID) Reveals Protein Targets of H2S Releasing Donors in Mammalian Cells (2016)

H2S is an important signalling molecule involved in diverse biological processes. It mediates the formation of cysteine persulfides (R-S-SH), which affect the activity of target proteins. Like thiols, persulfides show reactivity towards electrophiles and behave similarly to other cysteine modifications in a biotin switch assay. In this manuscript, we report on qPerS-SID a mass spectrometry-based method allowing the isolation of persulfide containing peptides in the mammalian proteome. With this method, we demonstrated that H2S donors differ in their efficacy to induce persulfides in HEK293 cells. Furthermore, data analysis revealed that persulfide formation affects all subcellular compartments and various cellular processes. Negatively charged amino acids appeared more frequently adjacent to cysteines forming persulfides. We confirmed our proteomic data using pyruvate kinase M2 as a model protein and showed that several cysteine residues are prone to persulfide formation finally leading to its inactivation. Taken together, the site-specific identification of persulfides on a proteome scale can help to identify target proteins involved in H2S signalling and enlightens the biology of H2S and its releasing agents.
Development of SiC power devices and modules for automotive motor drive use (2013)

SiC Power devices are expected to greatly improve the efficiencies and operating capabilities of next generation electric and hybrid electric vehicles. The use of these devices allows for drastic size and weight reduction at the module and system levels of motor drives used in automotive applications. A new SiC MOSFET structure with both gate and source trenches is presented. This greatly reduces device on-resistance while preventing oxide destruction at the gate trench bottoms. Finally new packaging methods under development are outlined that take advantage of the benefits these new devices have to offer by transfer molding them in a high temperature resistant epoxy resin. This leads to modules with low thermal resistance and high power density that, when configured as a three phase inverter, reduce total system footprint and parasitic inductance.