gebhart/patrepeval huggingface dataset:
Effect of Adhesion or Collagen Molecules on Cell Attachment, Insulin Secretion, and Glucose Responsiveness in the Cultured Adult Porcine Endocrine Pancreas: A Preliminary Study (2003)

The effect of either adhesion or collagen molecules on cell attachment, insulin secretion, and glucose responsiveness was investigated in adult porcine pancreatic endocrine (PE) cells that were cultured for a longer term in vitro. Six different types of molecules--laminin, fibronectin, poly-L-lysine (PLL), type I collagen, gelatin, and Matrigel--were used. Approximately 2.0 x 10(5) cells per dish of each molecule type were cultured for 4 weeks. In the laminin group, the insulin accumulation was maintained at a significantly higher level than in the control group at 4 weeks of culture, and glucose-stimulated insulin secretion and the insulin-positive rate were also higher than in the control group. In the Matrigel group, islet-like cell clusters were formed, but insulin accumulation rapidly decreased at 3-4 weeks of culture. A large number of PE cells attached tightly and spread in the fibronectin group until the fourth week of culture, but their function was not better than those in the control group. In the PLL and gelatin groups, the PE cell function was not significantly different from that of the control group. In the type I collagen group, insulin secretion was inferior to that of the other groups. The results of this study suggest that laminin is the most suitable extracellular matrix for the long-term culture preservation of PE cells.
Effect of processing on availability of iron salts in liquid infant formula products. Experimental soy isolate formulas (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of processing on availability of iron salts in liquid infant formula products. Experimental soy isolate formulasRichard C. Theuer, Kenneth S. Kemmerer, Wilbur H. Martin, Barry L. Zoumas, and Herbert P. SarettCite this: J. Agric. Food Chem. 1971, 19, 3, 555–558Publication Date (Print):May 1, 1971Publication History Published online1 May 2002Published inissue 1 May 1971https://pubs.acs.org/doi/10.1021/jf60175a017https://doi.org/10.1021/jf60175a017research-articleACS PublicationsRequest reuse permissionsArticle Views115Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
High-yield regioselective synthesis of 9-glycosyl guanine nucleosides and analogues via coupling with 2-<i>N</i>-acetyl-6-<i>O</i>-diphenylcarbamoylguanine (1987)

Treatment of 2-N,9-diacetylguanine with diphenylcarbamoyl chloride followed by heating with aqueous ethanol gave 2-N-acetyl-6-O-diphenylcarbamoylguanine (2-acetamido-6-diphenylcarbamoyloxypurine). Bis-trimethylsilylation of this product followed by coupling with glycosyl acetates (trimethylsilyl triflate catalysis) or α-haloethers in anhydroustoluene gave 9-substituted guanine compounds in high yields with no 7-isomers detected.
Electrical performance of phase change memory cells with Ge3Sb2Te6 deposited by molecular beam epitaxy (2015)

Here, we report on the electrical characterization of phase change memory cells containing a Ge3Sb2Te6 (GST) alloy grown in its crystalline form by Molecular Beam Epitaxy (MBE). It is found that the high temperature growth on the amorphous substrate results in a polycrystalline film exhibiting a rough surface with a grain size of approximately 80–150 nm. A detailed electrical characterization has been performed, including I-V characteristic curves, programming curves, set operation performance, crystallization activation at low temperature, and resistance drift, in order to determine the material related parameters. The results indicate very good alignment of the electrical parameters with the current state-of-the-art GST, deposited by physical vapor deposition. Such alignment enables a possible employment of the MBE deposition technique for chalcogenide materials in the phase change memory technology, thus leading to future studies of as-deposited crystalline chalcogenides as integrated in electrical vehicles.
Visual vertigo syndrome: clinical and posturography findings. (1995)

Neuro-otological and posturography findings in 15 patients with visually induced vertiginous symptoms (visual vertigo) are reported. Thirteen patients were considered to have a peripheral vestibular disorder; seven had abnormal caloric or rotational test results. Two patients had CNS disorder--a cerebellar degeneration and a brainstem stroke. Posturography testing showed that five patients showed abnormally large body sway induced by full field visual motion stimulation. This group included the two patients with CNS disease and four with strabismic symptoms (diplopia, squint surgery, and ocular muscle weakness). It is concluded that visual vertigo is a heterogeneous syndrome with peripheral or central aetiologies and may occur if patients with balance disorders show high visual field dependence. In patients with visual vertigo, the presence of additional CNS or strabismic symptoms may cause inappropriate postural reactions in environments with conflicting or disorienting visual stimuli, probably by reducing the ability to resolve the sensory conflict.
Use of Gelatin Particle Agglutination Test for the Detection of Cymbidium mosaic virus in Cattleya Plants (2001)

Gelatin particle agglutination test (GPAT) was used to detect Cymbidum mosaic virus (CymMV) in Cattleya plants. Gelatin particles were coated with purified anti-CymMV immunoglobulin of 25-100 /ml and were subjected to several different concentrations of purified CyMfV as well as varying dilutions of orchid leaf extracts. The GPAT detected purified CymMV up to a minimum concentration of 10 /ml. CymMV was detected from crude sap extract of infected Cattleya leaves and roots up to 1:51,200 and 1:25,600 dilutions, respectively. However, the optimum range of leaf and root sap dilutions was between 50-100. Non-specific reactions were not encountered from any of the healthy orchid plants tested. The entire GPAT process was completed within 2-3 hours. This test was found to be very useful for the detection of CymMV in orchids because it is sensitive, economical, and easy to perform.
Neuer Titelschutz von Software im Markengesetz (1995)

Une nouvelle loi concernant la protection des marques est entree en vigueur en Allemagne le 1er janvier 1995. Cette loi integre a present la protection juridique des titres en general et, par la meme, celle des titres de logiciels, qui beneficient maintenant d'une protection accrue. Cet article decrit la nouvelle reglementation.
An Improved Majority-Logic Decoder Offering Massively Parallel Decoding for Real-Time Control in Embedded Systems (2013)

We propose an easy-to-implement hard-decision majority-logic decoding algorithm for Reed-Muller codes RM(r,m) with m ≥ 3, m/2 ≥ r ≥ 1. The presented algorithm outperforms the best known majority-logic decoding algorithms and offers highly parallel decoding. The result is of special importance for safety- and time-critical applications in embedded systems. A simple combinational circuit can perform the proposed decoding. In particular, we show how our decoder for the three-error-correcting code RM(2, 5) of dimension 16 and length 32 can be realized on hardware level.
Role of ion energy in determination of the <i>sp</i>3 fraction of ion beam deposited carbon films (1996)

The role of ion energy over the range 5 eV≤E≤20 keV in the production of the dense diamondlike sp3-bonded phase of carbon films deposited from ion beams has been investigated. Films with a significant sp3 component (≳40%), as determined by electron energy loss spectroscopy (EELS), can be formed over the wide energy region 30 eV≤E≤10 keV at room temperature. The sp3 fraction is completely suppressed only for E≤10 eV or E≥20 keV. For both cases, this suppression is associated with a sharp increase of the surface roughness, as determined by atomic force microscopy (AFM). The different nature of the mechanisms responsible for the suppression of sp3 bonding in both the low and high energy regions is discussed.
Hormone-dependent androgen receptor phosphorylation is accompanied by receptor transformation in human lymph node carcinoma of the prostate cells (1991)

Phosphorylation of the androgen receptor was investigated in the absence of hormone as well as during and after transformation of the receptor to the tight nuclear binding form. Human prostate tumor cells (LNCaP) were labeled for 4 h with [32P]orthophosphate in the presence or absence of steroid. Subsequently, androgen receptors were immunoprecipitated either from total cell lysates or from nuclear extracts using a specific monoclonal antibody. The immunoprecipitated receptor preparations were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western blotting, using a polyclonal antiserum, and autoradiography. It was observed that the androgen receptor is already phosphorylated in the absence of hormone, but undergoes a hormone-induced additional phosphorylation. After administration of 10 nM R1881, a 1.8-fold increase in phosphorylation over nonstimulated control cells was reached. Moreover, the amount of nuclear extractable androgen receptor was increased; the acquisition of tight nuclear binding capacity was accompanied by hormone-induced receptor phosphorylation.
Pseudotumor of hemophilia in the orbit: The role of radiotherapy in management (1985)

A case of pseudotumor of hemophilia is presented that occurred in the right orbit of a boy with severe factor VIII deficiency and an inhibitor. After a period of observation and conservative management, low-dose radiotherapy (750 rads) and Proplex was used. Eighteen months after radiotherapy significant healing had occurred. The role of radiotherapy in the treatment of hemophilic pseudotumor is reviewed.
Immunosuppressive therapy for hypoplastic myelodysplastic syndrome (1997)

Treatment with ATG and CsA can be an attractive alternative for patients with hypoplastic MDS for whom there is no possibility of bone marrow transplantation.
Sensitive Solution-Processed Bi<sub>2</sub>S<sub>3</sub> Nanocrystalline Photodetectors (2008)

Solution-processed nanocrystal optoelectronic devices offer large-area coverage, low cost, and compatibility with a wide range of substrates. Recently, photodetectors and photovoltaics based on spin-coated nanoparticle films have shown tremendous progress in performance. However, high-performance devices reported to date have employed either Pb or Cd, raising concerns regarding environmental impact and regulatory acceptance. Herein we report a high-performance solution-processed photodetector based instead on Bi2S3 nanocrystals. The devices exhibit photoconductive gain on the order of 10 combined with temporal response on the 10 ms time scale. The resultant solution-processed Bi2S3 nanorod photoconductive photodetectors are of interest in visible and near-infrared (NIR) wavelength applications requiring video-frame-rate temporal response.
Array-Based Comparative Genomic Hybridization Analysis Identified Cyclin D1 as a Target Oncogene at 11q13.3 in Nasopharyngeal Carcinoma (2005)

Nasopharyngeal carcinoma is highly prevalent in Southern China and Southeast Asia. To unveil the molecular basis of this endemic disease, high-resolution comparative genomic hybridization arrays were used for systematic investigation of genomic abnormalities in 26 nasopharyngeal carcinoma samples. A comprehensive picture of genetic lesions associated with tumorigenesis of nasopharyngeal carcinoma was generated. Consistent chromosomal gains were frequently found on 1q, 3q, 8q, 11q, 12p, and 12q. High incidences of nonrandom losses were identified on chromosomes 3p, 9p, 11q, 14q, and 16q. In addition to previously characterized regions, we have identified several novel minimal regions of gains, including 3q27.3-28, 8q21-24, 11q13.1-13.3, and 12q13, which may harbor candidate nasopharyngeal carcinoma-associated oncogenes. In this study, gain of 11q13.1-13.3 was the most frequently detected chromosomal aberration and a 5.3-Mb amplicon was delineated at this region. Within this 11q13 amplicon, concordant amplification and overexpression of cyclin D1 (CCND1) oncogene was found in nasopharyngeal carcinoma cell lines, xenografts, and primary tumors. Knockdown of cyclin D1 by small interfering RNA in nasopharyngeal carcinoma cell lines led to significant decrease of cell proliferation. The findings suggest that cyclin D1 is a target oncogene at 11q13 in nasopharyngeal carcinoma and its activation plays a significant role in nasopharyngeal carcinoma tumorigenesis.
Contributors to the Fuel Economy Advantage of DISI Engines Over PFI Engines (2003)

<div class="htmlview paragraph">A methodology was developed, based on engine-simulation analysis and experiments, to evaluate quantitatively the contributions of the various factors on the fuel-economy advantage of direct-injection, spark-ignition (DISI) engines over corresponding port-fuel injection (PFI) engines. The fuel-economy comparison was based on a set of seven, steady-state test points, which simulate a 2400-kg vehicle powered by a 5.3-L V8 engine over the Federal Test Procedure (city cycle). The results show that the DISI engine has a 15% fuel-economy advantage over the corresponding PFI engine operating without EGR. The biggest positive contributor to this gain is the reduced pumping losses, which account for a 10% gain, followed by: favorable mixture properties due to lean/dilute operation with about a 7.5% gain, lower heat losses with a 2% gain, and higher compression ratio with a 3% gain. In contrast, the negative contributors (i.e., factors causing a decrease in fuel economy) were: lower combustion efficiency and combustion phasing losses which account for a 4% loss, and higher friction due to higher peak pressures, which yields a 4% loss. With further reduction of pumping losses, minimization of the surface area-to-volume ratio, and improvements in combustion through optimization of the phasing and improvements in the combustion efficiency, it may be possible for the DISI engine to achieve a 26% fuel economy improvement relative to a corresponding PFI engine.</div>
A global name service for a highly mobile internetwork (2014)

Mobile devices dominate the Internet today, however the Internet rooted in its tethered origins continues to provide poor infrastructure support for mobility. Our position is that in order to address this problem, a key challenge that must be addressed is the design of a massively scalable global name service that rapidly resolves identities to network locations under high mobility. Our primary contribution is the design, implementation, and evaluation of auspice, a next-generation global name service that addresses this challenge. A key insight underlying auspice is a demand-aware replica {placement engine} that intelligently replicates name records to provide low lookup latency, low update cost, and high availability. We have implemented a prototype of auspice and compared it against several commercial managed DNS providers as well as state-of-the-art research alternatives, and shown that auspice significantly outperforms both. We demonstrate proof-of-concept that auspice can serve as a complete end-to-end mobility solution as well as enable novel context-based communication primitives that generalize name- or address-based communication in today's Internet.
Remote process monitoring using optical fibre sensors (2003)

Conventional means of curing thermosetting resins used in advanced fibre reinforced composites involves heating the sample in an oven or autoclave where heat is transferred to the sample through conduction and convection. This conventional method for manufacturing composites involves long processing time. On the other hand, microwave-based processing offers the advantage of a significantly faster processing time where the heating occurs directly inside the sample. The use of microwave radiation however, necessitates the need for non-metallic cure monitoring systems. In this study, two remote (non-contact) sensor systems were designed and developed to facilitate spectral-based process monitoring inside a custom-modified commercial microwave oven. The two fibre optic sensor systems were (i) a non-contact optical fibre reflectance probe and (ii) a reusable transmission probe. Spectroscopic data were obtained using the fibre optic probes at specified microwave power levels. A low-cost temperature probe was developed in this current study and it was based on an optical fibre-based extrinsic Fabry-Perot interferometer (EFPI). The EFPI temperature sensor demonstrated an accuracy of /spl plusmn/1/spl deg/C over the range from ambient to 300/spl deg/C. The temperature of the resin system was also measured simultaneously along with the spectral data to monitor the progress of the chemical reaction (curing).
Bevirimat: A Novel Maturation Inhibitor for the Treatment of HIV-1 Infection (2008)

Existing antiretroviral treatments for HIV type-1 (HIV-1) disease are limited by problems of resistance and drug-drug interactions. Bevirimat is a novel HIV-1 maturation inhibitor with a mechanism of action that is distinct from other antiretroviral agents. Specific inhibition of the final rate-limiting step in Gag processing by bevirimat prevents release of mature capsid protein from its precursor (CA-SP1), resulting in the production of immature, non-infectious virus particles. Bevirimat inhibits replication of both wild-type and drug-resistant HIV-1 isolates in vitro, achieving similar 50% inhibitory concentration values with both categories. Serial drug passage studies have identified six single amino acid substitutions that independently confer bevirimat resistance. These resistance mutations occur at or near the CA-SP1 cleavage site, which is not a known target for resistance to other antiretroviral drugs. Bevirimat has demonstrated a consistent pharmacokinetic profile in healthy volunteers and HIV-infected patients, with peak plasma concentrations attained approximately 1-3 h after dosing. Plasma concentrations decrease in a log-linear manner with a mean plasma elimination halflife of 58-80 h, supporting once-daily dosing. Animal studies suggest that elimination of bevirimat is primarily by hepatic glucuronidation and hepatobiliary excretion. There is minimal renal elimination, with < 1% of the administered dose appearing in the urine. In responsive patients, bevirimat has demonstrated a robust dosedependent reduction in viral load (> 1.5 log10 copies/ml). Short-term administration (< or = 14 days) of bevirimat is well tolerated, even when used in combination with other antiretroviral agents. Further studies to evaluate the long-term efficacy and tolerability of bevirimat are currently underway.
Filter design for optical pattern recognition: multicriteria optimization approach (1990)

A method of constructing optimal multicriteria filters for optical pattern recognition is presented. In the particular case of synthetic discriminant function filters, this method is illustrated for double-optimization criteria, and filters that are not overspecialized are obtained, in contrast with traditional techniques. Furthermore, a rigorous comparison between different filters, with respect to the considered criteria, is provided with this approach.
Magnetic Investigation of Carbon Coated Co-, Ni- and Fe-Nanoparticles (2009)

Carbon coated cobalt-, nickel-and iron-nanoparticles were prepared by chemical method and their structural and magnetic properties were investigated. The samples were synthesized by carburization of the nanocrystalline form of the appropriate metal in CH4, followed up by the reduction of the obtained carbon deposits. The X-ray diffraction and transmission electron microscopy study revealed carbon coated Co-, Ni-and Fe-nanocapsules of the mean size ca. 50 nm, and a small amount of carbon nanotubes. The measurements of magnetization and AC susceptibility were carried out for samples with different carbon content. A special attention was paid to the low temperature magnetic behavior. Decrease in the saturation moment at T = 4.2 K due to the nanosize of the particles was stronger for the samples with higher carbon content, while the coercivity field (610 Oe, 330 Oe and 390 Oe, for Co-, Ni-, and Fe-particles, respectively) was independent of carbon content. From the temperature dependence of AC and DC susceptibility a wide size distribution of the particles and blocking temperature above room temperature could be expected.
Feline Haemoplasmen in der Schweiz: Identifikation einer neuen Spezies, Diagnose, Prävalenz und klinische Bedeutung (2006)

Two feline hemotropic mycoplasma spp. (aka hemoplasma) have previously been recognized. We recently discovered a third novel species in a cat with hemolytic anemia, designated 'Candidatus Mycoplasma turicensis', which is closely related to rodent haemoplasmas. This novel species induced anemia after experimental transmission to two SPF cats. Three quantitative real-time PCR assays were newly designed and applied to an epidemiological study surveying the Swiss pet cat population. Blood samples from 713 healthy and ill cats were analyzed. Up to 104 parameters per cat (detailed questionnaire, case history, laboratory parameters and retroviral infections) were evaluated. 'Candidatus Mycoplasma haemominutum' infection was more prevalent (8.5%) than Mycoplasma haemofelis (0.5%) and 'Candidatus Mycoplasma turicensis' (1%). Hemoplasma infections were associated with male gender, outdoor access, and old age, but not with disease or anemia. Infections were more frequently found in the South and West of Switzerland. Several hemoplasma infected cats, some acutely infected, others co-infected with FIV or FeLV, showed hemolytic anemia indicating that additional factors might play a role in the pathogenesis of the disease.
Extending asset management system functionality in bitcoin platform (2016)

Bitcoin is a digital payment system empowered by a distributed database called blockchain. The blockchain is an open ledger containing records of every transaction within Bitcoin system maintained by Bitcoin nodes all over the world. Because of its availability and robustness, the blockchain could be utilized as a record-keeping tool for information not related to any Bitcoin transactions. We propose a method of utilizing the blockchain of Bitcoin system to publish information by embedding an arbitrary size of data into Bitcoin transactions. By publishing information using the blockchain, the information also carries the characteristics of Bitcoin transaction: anonymous, decentralized, and permanent. The proposed protocol could be used to extend the functionality of asset management systems which are limited to a maximum of 80 bytes data. The proposed method also offers an efficiency of the transaction fee by 18 percent compared to Bitcoin Messaging protocol.