gebhart/patrepeval huggingface dataset:
Characterization of Panax ginseng UDP- Glycosyltransferases Catalyzing Protopanaxatriol and Biosyntheses of Bioactive Ginsenosides F1 and Rhl in Metabolically Engineered Yeasts (2015)

人参皂甙，在人参(人参属人参) 的主要 pharmacologically 活跃的自然混合物，主要是 protopanaxadiol (PPD ) 和 protopanaxatriol (PPT ) 的 glycosylated 产品。uridine diphosphate glycosyltransferase (UGT ) 催化 PPT 生产 PPT 类型人参皂甙，还都没被报导。这里，我们显示出那 UGTPg1，它 regio 明确地被表明了到 glycosylate C20 -- PPD 的 OH，另外明确地 glycosylates C20 -- PPT 到的 OH 生产 bioactive 人参皂甙 F1。我们报导四新奇 UGT 基因从 P.ginseng 孤立的 characterizationof，分享高推出的氨基酸身份(>84%) 与 UGTPg1。我们明确地表明那 UGTPg100 glycosylates C6 -- PPT 的 OH 催化 PPT 生产 bioactive 人参皂甙 Rh1，和 UGTPg101 生产 F1，从 F1 由人参皂甙 Rg1 的产生列在后面。然而， UGTPg102 和 UGTPg103 被发现不在 PPT 上举办可检测的活动。通过结构的建模和指导地点的 mutagenesis，我们识别了可以在决定他们的活动和底层 regio 特性起重要作用的这些 UGT 的几关键氨基酸。而且，我们由介绍遗传上设计的生产 PPT 小径和 UGTPg1 或 UGTPg100 构造了酵母 recombinants 到 biosynthesize F1 和 Rh1。我们的学习经由合成生物学策略在酵母为 bioactive PPT 类型人参皂甙在人参属工厂，和 providesa 声音生产途径揭示 PPT 类型人参皂甙的可能的 biosynthetic 小径。
Human chondrocyte expression of growth‐arrest‐specific gene 6 and the tyrosine kinase receptor axl. Potential role in autocrine signaling in cartilage (1997)

These findings present evidence for an autocrine signaling pathway in cartilage involving Gas-6 and the axl tyrosine kinase adhesion receptor. Stimulation of axl by Gas-6 may play an important role in the control of chondrocyte growth and survival.
Inheritance of Pollen Fertility Restoration in Cytoplasmic Male‐Sterile Upland Cotton<sup>1</sup> (1977)

Information regarding the inheritance of fertility restoration in cytoplasmic male‐sterile cotton will be a valuable tool in commercial production of F 1 hybrid cotton seed. F 1 , F 2 , and testcross populations were planted in 1975 at two locations to determine the inheritance of the fertility‐restoring factor in cytoplasmic male‐sterile Upland cotton ( Gossypium hirsutum L.). Fertility restoration in cytoplasmic male‐sterile cotton is controlled by a single gene probably expressing partial dominance. Either some of the F 2 plants were misclassifled or some minor modifying factor(s) was slightly deleterious to the growth and development of fertile plants in segregating populations. G. barbadense L. apparently has a factor that enhances pollen production in the F 1 hybrid. A breeding program is underway to transfer this factor(s) into Upland stocks. Fertile plants in segregating F 2 populations showed a significantly higher lint percentage than corresponding sterile plants. Higher micronaire was found for sterile plants than fertile plants.
Familial Influences on Conduct Disorder Reflect 2 Genetic Factors and 1 Shared Environmental Factor (2012)

CONTEXT: Prior studies suggest that antisocial behavior in childhood and adolescence reflects multiple symptomatic dimensions. However, to our knowledge, no prior study has evaluated the underlying nature of the etiologic influences contributing to conduct disorder (CD) symptoms as defined in the DSM. OBJECTIVE: To determine the structure of genetic and environmental risk factors for CD. DESIGN: Population-based twin registry. SETTING: Virginia. PARTICIPANTS: Two thousand seven hundred sixty-nine members of male-male twin pairs from the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. MAIN OUTCOME MEASURE: Retrospective self-reported symptoms of CD. RESULTS: The best-fitting multivariate twin model included 2 genetic factors, 1 shared environmental common factor, and 1 nonshared environmental common factor, along with criterion-specific genetic and nonshared environmental effects. The CD criteria with the strongest loadings on the 2 genetic factors were, respectively, those reflecting rule breaking (eg, playing hooky) and overt aggressive acts (eg, hurting people). The shared environ mental common factor had salient loadings on a distinct set of criteria reflecting covert delinquent acts (eg, stealing and hurting animals). Loadings on the single non-shared environmental common factor were more uniform and less selective. Scores on the 3 familial CD factors were differentially associated with a range of personality, psychopathology, and demographic factors. CONCLUSIONS: From a genetic perspective, the DSM criteria for CD do not reflect a single dimension of liability. The familial risk to CD is composed of 2 discrete dimensions of genetic risk, reflecting rule breaking and overt aggression, and 1 dimension of shared environmental risk, reflecting covert delinquency. These 3 familial factors differ meaningfully in their association with a range of relevant validators.
Es wurde noch nie soviel Radio gehört wie heute (1981)

Spätestens Ende der sechziger Jahre, als nämlich nahezu alle Haushalte in der Bundesrepublik über ein Fernsehgerät verfügten, wurde in der breiten Öffentlichkeit unseres Landes das Radio, der Hörfunk für endgültig tot erklärt. Wer sich entschloß, für dieses Medium zu arbeiten, galt als rückständig, als jemand, der die Zeichen der Zeit einfach nicht begreifen will.
Design of a Solar-Harvesting Circuit for Batteryless Embedded Systems (2009)

The limited battery lifetime of modern embedded systems and mobile devices necessitates frequent battery recharging or replacement. Solar energy and small-size photovoltaic (PV) systems are attractive solutions to increase the autonomy of embedded and personal devices attempting to achieve perpetual operation. We present a battery less solar-harvesting circuit that is tailored to the needs of low-power applications. The harvester performs maximum-power-point tracking of solar energy collection under nonstationary light conditions, with high efficiency and low energy cost exploiting miniaturized PV modules. We characterize the performance of the circuit by means of simulation and extensive testing under various charging and discharging conditions. Much attention has been given to identify the power losses of the different circuit components. Results show that our system can achieve low power consumption with increased efficiency and cheap implementation. We discuss how the scavenger improves upon state-of-the-art technology with a measured power consumption of less than 1 mW. We obtain increments of global efficiency up to 80%, diverging from ideality by less than 10%. Moreover, we analyze the behavior of super capacitors. We find that the voltage across the supercapacitor may be an unreliable indicator for the stored energy under some circumstances, and this should be taken into account when energy management policies are used.
Towards a workbench for acquisition of domain knowledge from natural language (1995)

In this paper we describe an architecture and functionality of main components of a workbench for an acquisition of domain knowledge from large text corpora. The workbench supports an incremental process of corpus analysis starting from a rough automatic extraction and organization of lexico-semantic regularities and ending with a computer supported analysis of extracted data and a semiautomatic refinement of obtained hypotheses. For doing this the workbench employs methods from computational linguistics, information retrieval and knowledge engineering. Although the work-bench is currently under implementation some of its components are already implemented and their performance is illustrated with samples from engineering for a medical domain.
Consolidation, Fragmentation, and the Disclosure of Trading Information (1995)

Journal Article Consolidation, Fragmentation, and the Disclosure of Trading Information Get access Ananth Madhavan Ananth Madhavan University of Southern California Address all correspondence to Ananth Madhavan, School of Business Administration, University of Southern California, Los Angeles, CA 90089-1421. Search for other works by this author on: Oxford Academic Google Scholar The Review of Financial Studies, Volume 8, Issue 3, July 1995, Pages 579–603, https://doi.org/10.1093/rfs/8.3.579 Published: 28 May 2015
Abstract 3998: Proton Pump Inhibitors Effect on Clopidogrel Effectiveness: The Clopidogrel Medco Outcomes Study (2008)

Background: The anti-platelet properties of clopidogrel are thought to be activated by cytochrome P450 2C19. This isoenzyme is potently inhibited by the most commonly prescribed proton pump inhibitors (PPIs) and therefore may interfere with clopidogrel activation and its anti-platelet effects. Methods: We investigated the potential impact of PPIs on the effectiveness of clopidogrel to prevent coronary artery stent re-stenosis through a retrospective cohort study using the National Medco Integrated Database file, which covers approximately 19 million lives. We selected patients who underwent stent placement at sometime during a one-year period in 2005–2006, who started taking clopidogrel at the time of stent placement, and who were at least 80% compliant during the ensuing year (n=14,383). We followed these patients for the one-year incidence of major adverse CV events: hospitalization for stroke, MI, angina or CABG. We compared those who took clopidogrel alone (n=9862) vs. those who took clopidogrel with PPIs (n=4521), adjusting for baseline differences in age, gender and comorbidity. Results: Stent patients with no preceding CV events taking PPIs with clopidogrel showed a 32.5% incidence of a major CV event within one year vs. 21.2% of patients not taking PPIs (adjusted OR 1.79, CI 1.62–1.97). A more pronounced effect was seen among patients with a preceding CV event; 39.8% vs 26.2% (adjusted OR of 1.86, CI 1.63–2.12). Conclusions: Our findings suggest that the drug interaction between PPIs and clopidogrel may result in serious adverse outcomes within one year of therapy initiation, and further support investigations into the effects of cytochrome P450 2C19 genetic polymorphisms.
Generation of the fifth harmonic of picosecond yttrium aluminate laser radiation (1989)

An investigation was made of the generation of the fifth harmonic of the radiation emitted by a picosecond Nd3+-activated yttrium aluminate laser. The harmonic was generated by three different methods using KDP and potassium pentaborate crystals. An optimal method was developed for generating the fifth harmonic (λ = 216 nm) with an output energy of 0.5 mJ in the form of pulses of 15-ps duration.
Successful Use of Vacuum-Assisted Closure Therapy for Leg Ulcers Caused by Occluding Vasculopathy and Inflammatory Vascular Diseases – A Case Series (2007)

Our experience shows VAC to be an excellent and effective alternative in the treatment of therapy-resistant chronic wounds caused by vasculopathy (small vessel occlusion or vasculitis). We did not observe any pathergy or proinflammatory effects caused by VAC.
The Pharmacology and Use of H<sub>1</sub>-Receptor-Antagonist Drugs (1994)

The second-generation H1-antagonist drugs are supplanting their predecessors in the treatment of allergic rhinoconjunctivitis and chronic urticaria. Their use can be justified mainly on the basis of a more favorable risk-benefit ratio, because they are less toxic to the central nervous system. Future research into H1 antagonists should include additional dose-response studies in patients with allergic disorders, especially children and the elderly; objective studies of adverse effects; studies of topical mucosal application of H1 antagonists; and studies of H1-antagonist enantiomers and active metabolites. With the cloning of the gene encoding the H1 receptor and increased understanding of the precise structural requirements for H1-receptor activity, H1 antagonists with an even more favorable therapeutic index may be developed.
Observations of geomagnetic pulsations and variations with a new borehole magnetometer down to depths of 3000 m (1993)

A triaxial magnetometer has been developed for investigating the in situ skin effect of horizontal geomagnetic pulsations and variations in deep boreholes. The observations were carried out in the pilot borehole of the Continental Deep Drilling Program of Germany (KTB) down to depths of 3000 m and up to temperature of 90 °C. A weak skin effect, due to the known very low conductivity of the penetrated crystalline rocks, of 90 to 95 per cent in amplitude and -5° to -10° rotation in phase has been observed at periods of 10 s and magnetometer depth of 2400 m. An essential prerequisite for all calculations is the accurate determination of the orientation of the downhole magnetometer. It is demonstrated how oriented record samples of temporal variations at depth correlate precisely with those from the surface. Results from surface magnetotelluric (MT) investigations show strong local distortions of the telluric field. The distortion of the MT tensor response has been determined by means of newly introduced skin-effect transfer functions, which are assumed to be undistorted.
Utility of Monoclonal Antibodies Directed Against B and T Lymphocytes and Monocytes in Paraffin-embedded Sections (1983)

Monoclonal antibodies reactive with B and T lymphocytes, monocytes, and granulocytes were applied to B-5-, Bouin's-, or formalin-fixed paraffin-embedded sections. Most antigens were destroyed or masked by fixation or embedding procedures, or both. However, T200, an antigen present in all lymphoid and hematopoietic cells, and Leu M1, an antigen in granulocytes, were well preserved in formalin-fixed tissues. Leu 1 and BA-1, antigens present on T and B lymphocytes, respectively, were preserved in Bouin's-fixed specimens. With careful selection of fixatives, identification of some T and B lymphocytes and granulocytes by monoclonal antibodies in paraffin-embedded specimens is possible.
Immunoglobulin isotypes of anti-Trichomonas vaginalis antibodies in patients with vaginal trichomoniasis (1986)

Studies of anti-Trichomonas vaginalis antibodies in patients with vaginal trichomoniasis were undertaken in attempts to identify the predominant antibody isotype produced and to delineate clinically significant antigens. The total antibody content of serum samples from 23 patients was determined by an enzyme-linked immunosorbent assay (ELISA) that employed anti-human immunoglobulin and isotype-specific antisera. The immunochemical reactivity of these antibodies was examined by Western blot analysis. The anti-T. vaginalis titer of all but two of these serum samples was greater than 200 (range, greater than 200 to 12,800). By using an ELISA titer of at least 200 as a criterion, 21 of the serum samples contained antibodies of the immunoglobulin G (IgG) isotype, 17 contained IgM antibodies, and 6 contained IgA antibodies directed to the protozoan. Western blot analyses of these serum samples revealed approximately 29 antigenic trichomonad polypeptides, with apparent molecular sizes ranging from 14 to greater than 100 kilodaltons and with individual serum samples possessing different patterns of reactivity. These results add to the current understanding of the serological and secretory immune responses to T. vaginalis, as well as define potential antigens for use in immunodiagnostics.
Plasma simulation by artificial dielectrics and parallel-plate media (1962)

A plasma in the absence of dc magnetic fields is representable, from the electromagnetic viewpoint, as a lossy dielectric with a complex index of refraction whose real part is less than one. Its electrical properties, such as propagation constant and intrinsic impedance, can be simulated by microwave structures, such as artificial dielectrics of lossy metallic rods, and by <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">H</tex> - plane parallel-plate guides. Design techniques are presented for application to the modeling of plasma media. Examples include problems of radiation from antennas on a plasma-coated ground plane, with magnetic line sources and electric aperture radiators simulated by parallel-plate guides and rodded media, respectively. Radiation patterns of these models show good agreement with established theory. Waveguide measurements on the rodded media also confirm the expected propagation and impedance characteristics.
4—THERMAL DEGRADATION OF FABRICS AND YARNS PART I: FABRICS (1984)

An investigation is reported in which fabrics were exposed to elevated temperatures for different times and the changes in dimensional stability, tear-resistance, breaking strength, and colour were determined. For tear-resistance and breaking strength, polyester-fibre fabrics were less affected by heat than the other fabrics tested. The polyester-fibre fabrics also retained their white appearance after all heat treatments, whereas all the other fabrics changed colour appreciably. The dimensional stabilities for fabrics were all quite good, with nylon and polyester-fibre fabrics shrinking more than the others. Tear-resistance was reduced appreciably more than breaking strength for all fabrics, with FR fabrics losing more than the untreated fabrics. A suggestion is made for calculating, from the Arrhenius equation, the useful life of a fabric at any elevated temperature.
Magnetic Clusters in Molecular Beams, Metals, and Semiconductors (1996)

The evolution of magnetic order from the microscopic to the macroscopic regime may be studied with the use of nanometer-scale clusters. A variety of new techniques can be employed to control the size of the magnetic clusters from the atomic level. Molecular beams are used to construct and measure the magnetic properties of isolated metallic clusters. Superparamagnetic metallic particles embedded in a metal exhibit dramatic field-dependent changes in electrical conduction, providing a measure of spin-dependent scattering. Related efforts in semiconductor hosts with the use of ion implantation have generated room-temperature ferromagnetic clusters that can be directly imaged by magnetic force microscopy.
14th Topical Meeting on the Technology of Fusion Energy (2001)

(2001). 14th Topical Meeting on the Technology of Fusion Energy. Fusion Technology: Vol. 39, Proceedings of the Fourteenth Tropical Meeting on The Technology of Fusion Energy. October 15-19, 2000. Park City, Utah, pp. xvi-xvi.
Understanding the real-world performance of carrier sense (2005)

Carrier sense is a fundamental part of most wireless networking stacks in wireless local area- and sensor networks. As increasing numbers of users and more demanding applications push wireless networks to their capacity limits, the efficacy of the carrier sense mechanism becomes a key factor in determining wireless network capacity.We describe how carrier sense works, point out its limitations, and advocate an experimental approach to studying carrier sense. We describe our current testbed setup, and then present preliminary experimental results from both a 60-node sensor network deployment and a small-scale 802.11 deployment. Our preliminary results evaluate how well carrier sense works and expose its limitations.
Charge stability in LPCVD silicon nitride for surface passivation of silicon solar cells (2010)

Negatively charged dielectric films are of great interest for application to silicon solar cells, since such films offer the possibility of excellent passivation of p type surfaces. This paper investigates the distribution and stability of negative charge in silicon dioxide / LPCVD silicon nitride films which have been negatively charged through the injection of electrons from the silicon substrate. High densities of negative charge (5-10×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</sup> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> ) can be stored in the silicon nitride films. The negative charge is determined to be mainly concentrated at the oxide/nitride interface. The thermal stability of the charge is shown to be improved by the presence of a barrier layer on top of the silicon nitride. Modelling indicates that the thermal stability is likely to be sufficient for application to solar cells, which will operate at elevated temperatures for 25 years or more.
Infrared chemiluminescence and energy partitioning from reactions of fluorine atoms with hydrides of carbon, silicon, oxygen, sulfur, nitrogen, and phosphorus (1973)

The HF† infrared chemiluminescence from the reactions of fluorine atoms with PH3, SiH4, H2O, H2O2, H2S, NH3, N2H4, and three additional carbon compounds, (CH3)2O, (CH3)2S, and (CH3)3N, was studied in the same way as described in the preceding paper. With the exceptions of the N2H4 reaction, a large fraction of the energy, ≳ 45%, was released as vibrational energy of the HF† product, and population inversions were frequently found. The strong chemical interaction between HF† and NH3, (CH3)3N, N2H4, and PH3 may have led to efficient vibrational relaxation for these reactions; however, the redissociation of the adducts may give mainly HF† (v = 0), and modification of the vibrational distribution may not be severe. The results can be used to establish upper limits to some uncertain bond energies: D(SiH3–H)≤ 87 kcal mole−1; D(PH2–H)≤ 78 kcal mole−1, D(NH2–H)≤ 110 kcal mole−1 and D(N2H3–H)≤ 85 kcal mole−1. Since these F atom reactions tend to populate vibrational levels up to the maximum allowed by the thermochemistry, these limits with the exception of D(H–N2H3), which has a substantial uncertainty, probably are within 5 kcal mole−1 of the actual bond energy. Although rotational relaxation was only partially arrested, a sizeable amount of HF† rotational energy was found from the (CH3)2O, (CH3)2S, PH3, and SiH4 reactions. The (CH3)2O and (CH3)2S reactions partition more rotational energy and less vibrational energy to HF† than the reactions with most other primary C–H bonds.
Hydrolysis of polysaccharide sulphate esters by a sulphatase preparation from <i>Charonia lampas</i> (1961)

Research Article| August 01 1961 Hydrolysis of polysaccharide sulphate esters by a sulphatase preparation from Charonia lampas N TAKAHASHI; N TAKAHASHI Search for other works by this author on: This Site PubMed Google Scholar F EGAMI F EGAMI Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1961) 80 (2): 384–386. https://doi.org/10.1042/bj0800384 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation N TAKAHASHI, F EGAMI; Hydrolysis of polysaccharide sulphate esters by a sulphatase preparation from Charonia lampas. Biochem J 1 August 1961; 80 (2): 384–386. doi: https://doi.org/10.1042/bj0800384 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1961 The Biochemical Society1961 Article PDF first page preview Close Modal You do not currently have access to this content.