gebhart/patrepeval huggingface dataset:
Kinetics of selective epitaxial deposition of Si1−<i>x</i>Ge<i>x</i> (1992)

The kinetics of selective deposition of epitaxial Si1−xGex layers in an atmospheric-pressure reactor have been examined. Adding HCl to the SiH2Cl2/GeH4/H2 system decreases the Si component of the deposition rate more than the Ge component, increasing the Ge fraction in the deposited layer. HCl addition also decreases boron incorporation. When deposited selectively on oxide-patterned wafers, lateral transport of the depositing materials causes the deposition rate and the Ge fraction to be higher in small patterns than in large patterns and also to be higher near the edges of patterns than at their centers.
HIV-1 subtype B’ dictates the AIDS epidemic among paid blood donors in the Henan and Hubei provinces of China (2003)

Our data indicate that the AIDS epidemic among PBD in Henan and Hubei is caused largely by HIV-1 subtype B', which contrasts greatly with the CB' recombinant strains CRF-07 and CRF-08 currently dominating among the drug abusers in other regions of China. Our report has revealed the first complete genome background of the most dominant circulating HIV-1 strain in Henan and Hubei, which is essential for the design and development of an effective AIDS vaccine for the region.
Graph-based data integration and business intelligence with BIIIG (2014)

We demonstrate BIIIG (Business Intelligence with Integrated Instance Graphs), a new system for graph-based data integration and analysis. It aims at improving business analytics compared to traditional OLAP approaches by comprehensively tracking relationships between entities and making them available for analysis. BIIIG supports a largely automatic data integration pipeline for metadata and instance data. Metadata from heterogeneous sources are integrated in a so-called Unified Metadata Graph (UMG) while instance data is combined in a single integrated instance graph (IIG). A unique feature of BIIIG is the concept of business transaction graphs, which are derived from the IIG and which reflect all steps involved in a specific business process. Queries and analysis tasks can refer to the entire instance graph or sets of business transaction graphs. In the demonstration, we perform all data integration steps and present analytic queries including pattern matching and graph-based aggregation of business measures.
Optimization Scheme to Minimize Reference Resistance Distribution of Spin-Transfer-Torque MRAM (2013)

Spin-transfer-torque magnetoresistive random access memory (STT-MRAM) is an emerging type of nonvolatile memory with compelling advantages in endurability, scalability, speed, and energy consumption. As the process technology shrinks, STT-MRAM has limited sensing margin due to the decrease in supply voltage and increase in process variation. Furthermore, the relatively smaller resistance difference of two states in STT-MRAM poses challenges for its read/write circuit design to maintain an acceptable sensing margin. The proposed reference circuits optimization scheme solves the reference resistance distribution issue to maximize the sensing margin and minimize the read disturbance, with low power consumption. Simulation results show that the optimization scheme is able to significantly improve the read reliability with the presence of one or few cases of reference cell failure, thus it eliminates the requirement of additional circuits for failure detection of reference cell or referencing to neighboring blocks.
Preparation and Characterization of Monoclonal Antibodies to Human Neutrophil Cathepsin G, Lactoferrin, Eosinophil Peroxidase, and Eosinophil Major Basic Protein (1989)

This report describes the production and characterization of five murine monoclonal antibodies that react with granule proteins of human granulocytes. Monoclonal antibody AHN-11 (IgG2a) reacted specifically with neutrophil cathepsin G; no reactivity with the homologous neutrophil neutral proteases, elastase, proteinase 3, or esterase N was detected. Antibodies AHN-9 (IgG1) and AHN-9.1 (IgG2b) each reacted with different epitopes on human lactoferrin, but not with the homologous protein transferrin. Two IgG1 antibodies, AHE-1 and AHE-2, reacted specifically with eosinophils; AHE-1 reacted strongly with eosinophil peroxidase but not eosinophil major basic protein while AHE-2 recognized eosinophil major basic protein but not eosinophil peroxidase. All five antibodies could detect their respective antigens in alcohol-fixed cytospin preparations. These antibodies should be useful for immunolocalization and quantification of their respective antigens as well as for other studies of the roles of these proteins in granulocyte function and differentiation.
Entwicklung von chiralen Katalysatoren durch kombinatorische Ligandenvariation – Ti‐katalysierte enantioselektive Addition von TMSCN an <i>meso</i>‐Epoxide (1996)

Die erste katalytische und enantioselektive Ringöffnung von meso ‐Epoxiden mit Trimethylsilylcyanid (TMSCN) wurde durch schrittweise Modifikation des modular aufgebauten Liganden, einer Dipeptid‐Schiff‐Base, erreicht [Gl. (a)]. Bei der Optimierung der asymmetrischen Induktion kamen kombinatorische Verfahren und die Festphasensynthese sowie das Screening der so parallel hergestellten Peptid‐Liganden zum Einsatz. magnified image
T and B Lymphocytes in the Regulation of Delayed Hypersensitivity (1976)

Abstract A correlation was demonstrated between the transient nature of a) delayed intradermal responses of guinea pigs sensitized to hen egg albumin in incomplete Freund's adjuvant, and b) the proliferative response of sensitized lymphocytes to the specific antigen. Spleen cells from sensitized animals suppressed the proliferative response of lymph node cells to specific antigen. This suppression was dependent on the dose of spleen cells and the time of their removal after sensitization. Thymus cells were suppressive to a lesser extent, and their activity was not correlated with the time of removal after sensitization. Separation of spleen and thymus cells into T and B populations indicated that the B cell was the major suppressor cell in the spleen, while the T cell in the thymus had a similar but less pronounced action.
DBD––taxonomically broad transcription factor predictions: new content and functionality (2007)

DNA-binding domain (DBD) is a database of predicted sequence-specific DNA-binding transcription factors (TFs) for all publicly available proteomes. The proteomes have increased from 150 in the initial version of DBD to over 700 in the current version. All predicted TFs must contain a significant match to a hidden Markov model representing a sequence-specific DNA-binding domain family. Access to TF predictions is provided through http://transcriptionfactor.org, where new search options are now provided such as searching by gene names in model organisms, searching for all proteins in a particular DBD family and specific organism. We illustrate the application of this type of search facility by contrasting trends of DBD family occurrence throughout the tree of life, highlighting the clear partition between eukaryotic and prokaryotic DBD expansions. The website content has been expanded to include dedicated pages for each TF containing domain assignment details, gene names, links to external databases and links to TFs with similar domain arrangements. We compare the increase in number of predicted TFs with proteome size in eukaryotes and prokaryotes. Eukaryotes follow a slower rate of increase in TFs than prokaryotes, which could be due to the presence of splice variants or an increase in combinatorial control.
Resource Scheduling For Heterogeneous Traffic in LTE Virtual Networks (2015)

Cellular network virtualization is being considered as a key trend in future mobile networks towards improved resource utilization. However, virtualization scenarios need in- vestigation to understand the considerations which should be taken into account when deploying virtualized wireless networks in practice. Towards this, we address the performance of a virtualized network in the presence of heterogeneous classes of traffic. In previous cellular network virtualization literature, both Realtime (RT) and Non-Realtime (NRT) traffic requests have been included without distinction. Both types are provisioned using the same algorithm for allocation of resources specified by the Network Scheduler (1). However, different types of traffic have different characteristics (2), e.g., RT requests are delay sensitive but may need fixed bandwidth, and hence should be treated differently, especially when wireless channel conditions are factored into the scheduling. We recognize this difference and in this paper, we propose a new approach to improve scheduling of resources for RT and NRT traffic. In particular, we prioritize the traffic belonging to different virtual slices from all service providers (SP/VEs) at the Network Scheduler before allocating resources to different SP/VEs, i.e., we form a Virtual Prioritized Slice (VPS). The virtual prioritized slice is forwarded to the VPS scheduler to serve all RT requests first. Only after the RT traffic is scheduled, the NRT traffic is provisioned using proportional fairness (PF) scheduling. We show by simulation results that this new VPS approach helps outperform recently proposed resource allocation schemes.
Modern Organic Synthesis with α-Diazocarbonyl Compounds (2015)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTModern Organic Synthesis with α-Diazocarbonyl CompoundsAlan Ford†, Hugues Miel§, Aoife Ring†, Catherine N. Slattery†, Anita R. Maguire*†‡, and M. Anthony McKervey*∥View Author Information† ‡ †Department of Chemistry and ‡School of Pharmacy, Analytical and Biological Chemistry Research Facility, Synthesis and Solid State Pharmaceutical Centre, University College Cork, Cork, Ireland§ Almac Discovery Ltd., David Keir Building, Stranmillis Road, Belfast BT9 5AG, United Kingdom∥ Almac Sciences Ltd., Almac House, 20 Seagoe Industrial Estate, Craigavon BT63 5QD, United Kingdom*E-mail: [email protected]*E-mail: [email protected]Cite this: Chem. Rev. 2015, 115, 18, 9981–10080Publication Date (Web):August 18, 2015Publication History Received26 February 2015Published online18 August 2015Published inissue 23 September 2015https://pubs.acs.org/doi/10.1021/acs.chemrev.5b00121https://doi.org/10.1021/acs.chemrev.5b00121review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views34843Altmetric-Citations1245LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Addition reactions,Catalysts,Insertion reactions,Rearrangement,Stereoselectivity Get e-Alerts
원저 : 진행위암에 대한 5-Fluorouracil , Cisplatin ( FP ) 복합화학요법의 치료 효과 (1993)

Background: Patients with unresectable or advanced gastric cancer require palliative systemic chemotherapy. Recently, cisplatin has been reported to be an effective agent against gastric cancer. And in vitro synergism between 5-fluorouracil and cisplatin was demonstrated in the L1210 leukemia model. Therefore we performed a phase II trial to assess the response rate and toxicity of the combination regimen with 5-fluorouracil infusion and cisplatin for patients with advanced gastric cancer. Method: Thirty-six patients with previous untreated gastric cancer and measurable diseases were treated with a combination of 5-fluorouracil and cisplatin. The regimen consisted of 5-fluorouracil, 1,000mg/m2/day, by a 12-hour continuous infusion on day 1 to 5 and cisplatin, 60 mg/m2/day, iv bolus on day 1, and the treatments were repeated every 3 weeks. Result: 1) Among 34 evaluable patients, 21 patients (62%) achieved partial responses, and the median duration of response was 5.7 months. 2) The median survival of overall patients was 8.1 months. The median survival of the responders was 9.3 months and that for nonresponders, 3.8 months. 3) Age, sex, gastrectomy, weight loss, histologic grade did not influenced prognosis. Among the performance status, 0-1 groups were more responsive to the treatment and longer survival time than 2-3 group (p<0.005). 4) Toxicites were common but well tolerated. Conclusion: A combination chemotherapy of 5-fluorouracil and cisplatin in patients with advanced gastric cancer seems to be effective and well tolerated.
Pre‐stack stratigraphic inversion and attribute analysis for optimal reservoir characterisation (2003)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2003Pre‐stack stratigraphic inversion and attribute analysis for optimal reservoir characterisationAuthors: Anne‐Sophie BarnolaBenoit AndrieuxThierry TonellotOlivier VoutayAnne‐Sophie BarnolaBeicip‐Franlab, France, Benoit AndrieuxInstitut Français du Pétrole, France, Thierry TonellotInstitut Français du Pétrole, France, and Olivier VoutayInstitut Français du Pétrole, Francehttps://doi.org/10.1190/1.1817576 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1817576FiguresReferencesRelatedDetailsCited ByLow‐frequency constrain in a priori model building for stratigraphic inversionP. Nivlet3 January 2005 SEG Technical Program Expanded Abstracts 2003ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2003 Pages: 2452 publication data© 2003 Copyright © 2003 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 03 Jan 2005 CITATION INFORMATION Anne‐Sophie Barnola, Benoit Andrieux, Thierry Tonellot, and Olivier Voutay, (2003), "Pre‐stack stratigraphic inversion and attribute analysis for optimal reservoir characterisation," SEG Technical Program Expanded Abstracts : 1493-1496. https://doi.org/10.1190/1.1817576 Plain-Language Summary PDF DownloadLoading ...
Properties of a M(r) 110,000 tumor rejection antigen of the chemically induced BALB/c Meth A sarcoma. (1993)

A M(r) 110,000 glycoprotein, designated gp110, isolated from the concanavalin A-Sepharose-binding protein fraction of the chemically induced BALB/c Meth A sarcoma by Mono Q fast protein liquid chromatography, has been shown to: (a) increase the resistance of these mice to growth of the Meth A sarcoma, but not the antigenically unrelated BALB/c CI-4 sarcoma, and (b) induce an antitumor cellular immune response in mice, which was detectable in cell-mediated cytotoxic assays. The immunogenicity of the concanavalin A-Sepharose-binding protein fraction of Meth A cytosol had been attributed to gp96, the major component of this fraction. The evidence presented here, however, demonstrates that Meth A gp96, when sufficiently purified, is nonimmunogenic. The results of the present analysis of gp110 strongly support the concept that gp110 represents a family of proteins expressed on a variety of chemically induced tumors, in which variations in molecular fine structure account for the antigenic diversity associated with these tumors.
Why the Reactive Oxygen Species of the Fenton Reaction Switches from Oxoiron(IV) Species to Hydroxyl Radical in Phosphate Buffer Solutions? A Computational Rationale (2019)

It has been shown that the major reactive oxygen species (ROS) generated by the aqueous reaction of Fe(II) and H<sub>2</sub>O<sub>2</sub> (i.e., the Fenton reaction) are high-valent oxoiron(IV) species, whereas the hydroxyl radical plays a role only in very acidic conditions. Nevertheless, when the Fenton reaction is conducted in phosphate buffer solutions, the resulting ROS turns into hydroxyl radical even in neutral pH conditions. The present density functional theory (DFT) study discloses the underlying principle for this phenomenon. Static and dynamic DFT calculations indicate that in phosphate buffer solutions, the iron ion is highly coordinated by phosphoric acid anions. Such a coordination environment substantially raises the p<i>K</i> <sub>a</sub> of coordinated water on Fe(III). As a consequence, the Fe(III)-OH intermediate, resulting from the reductive decomposition of H<sub>2</sub>O<sub>2</sub> by ferrous ion is relatively unstable and will be readily protonated by phosphoric acid ligand or by free proton in solution. These proton-transfer reactions, which become energetically favorable when the number of phosphate coordination goes up to three, prevent the Fe(III)-OH from hydrogen abstraction by nascent <sup>•</sup>OH to form Fe(IV)=O species. On the basis of this finding, a ligand design strategy toward controlling the nature of ROS produced in the Fenton reaction is put forth. In addition, it is found that while phosphate buffers facilitate <sup>•</sup>OH radical generation in the Fenton reaction, phosphoric acid anions can act as <sup>•</sup>OH radical scavengers through hydrogen atom transfer reactions.
Back to the Future: A Framework for Automatic Malware Removal and System Repair (2006)

Malware, software with malicious intent, has emerged as a widely-spread threat to system security. It is difficult to detect malware reliably because new and polymorphic malware programs appear frequently. It is also difficult to remove malware and repair its damage to the system because it can extensively modify a system. We propose a novel framework for automatically removing malware from and repairing its damage to a system. The primary goal of our framework is to preserve system integrity. Our framework monitors and logs untrusted programs' operations. Using the logs, it can completely remove malware programs and their effects on the system. Our framework does not require signatures or other prior knowledge of malware behavior. We implemented this framework on Windows and evaluated it with seven spyware, trojan horses, and email worms. Comparing our tool with two popular commercial anti-malware tools, we found that our tool detected all the malware's modifications to the system detected by the commercial tools, but the commercial tools overlooked up to 97% of the modifications detected by our tool. The runtime and space overhead of our prototype tool is acceptable. Our experience suggests that this framework offers an effective new defense against malware.
Influence of ascorbic acid supplementation on the toxic effects of dietary histamine in chicks. (1987)

ニワトリヒナに対するヒスタミンの有害作用をアスコルビン酸(AA)により緩和できるかどうかを調べるために,白色レグホーン種雄初生ヒナに0.1～0.3%ヒスタミン添加飼料を給与した際における1.5%AAの同時添加の影響について調べた。1. ヒナの成長はヒスタミン添加飼料の給与によって抑制され,飼料摂取量も低下した。とくに有害作用の強くあらわれた0.2%および0.3%のヒスタミン添加の場合には,AAの同時添加により成長は改善され,飼料摂取量も増加した。2. ヒスタミンの添加量が多い場合には,腺胃および筋胃に対する影響が強くあらわれた。すなわち,0.2%以下上のヒスタミン添加によって腺胃重量が,0.3%のヒスタミン添加では筋胃重量も有意に増加した。また,腺胃の異常や筋胃のびらん(GE)などの発症程度も高かった。しかし,AAの同時添加により腺胃および筋胃の重量増加は軽減され,腺胃の異常やGEは防止された。3. 血漿,肝臓および腎臓のAA量は1.5%AA添加によりいずれも有意に増加したが,ヒスタミン添加の影響はとくに認められなかった。また,血液と肝臓のヒスタミン量については,ヒスタミンあるいはAA添加と関連した一定の傾向の変動はみられなかった。4. 以上のことから,ニワトリヒナに対する成長阻害ならびにGEなどのヒスタミンの有害作用はAAによって緩和できることが示された。
3-D Rigid Body Tracking Using Vision and Depth Sensors (2013)

In robotics and augmented reality applications, model-based 3-D tracking of rigid objects is generally required. With the help of accurate pose estimates, it is required to increase reliability and decrease jitter in total. Among many solutions of pose estimation in the literature, pure vision-based 3-D trackers require either manual initializations or offline training stages. On the other hand, trackers relying on pure depth sensors are not suitable for AR applications. An automated 3-D tracking algorithm, which is based on fusion of vision and depth sensors via extended Kalman filter, is proposed in this paper. A novel measurement-tracking scheme, which is based on estimation of optical flow using intensity and shape index map data of 3-D point cloud, increases 2-D, as well as 3-D, tracking performance significantly. The proposed method requires neither manual initialization of pose nor offline training, while enabling highly accurate 3-D tracking. The accuracy of the proposed method is tested against a number of conventional techniques, and a superior performance is clearly observed in terms of both objectively via error metrics and subjectively for the rendered scenes.
Lack of Hepatic Enzymatic Adaptation to Low andHigh Levels of Dietary Protein in the Adult Cat (1977)

The activities of three urea cycle enzymes, several nitrogen catabolic, gluconeogenic,and lipogenic enzymes were measured in the liver of adult cats fed: a commercial kibble; a 17.5 or 70% protein purified diet, or starved for 5 days. Except for an increase in tyrosine transaminase(EC 2.6.1.5) after feeding the high protein diet, there were no changes in the activities of the hepatic enzymes as influenced by dietary protein level. Likewise, starvation had a minimal effect on the activities of these enzymes as compared to that found in similar experiments in rats. These results indicate that the cat may have only minimal capabilities for enzyme adaptation as compared to that found in many herbivores and omnivores and may provide an explanation as to why cats have an unusually high protein requirement as compared to many other mammals.
Demonstration of Chemisorption of Carbon Dioxide in 1,3‐Dialkylimidazolium Acetate Ionic Liquids (2011)

Real chemistry: Spectroscopic and crystallographic analyses confirm the chemical reaction of CO2 with carbene present in 1,3-dialkylimidazolium acetate ionic liquids and the supporting role of the acetate ion. When CO2 was bubbled through [C2mim][OAc], formation of the corresponding imidazolium carboxylate, [C2mim+-COO−], could be observed. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
고추와 토마토 종자에서 종자전염 세균 및 바이러스의 동시 검출을 위한 One-step Multiplex RT-PCR 방법 (2011)

The aim of this study was to develop specific and sensitive PCR-based procedures for simultaneous detection of economically important plant seed infection pathogenic bacteria and virus, Xanthomonns campestris pv. vesicatoria (Xcv), Clavibacter michiganensis subsp. michiganensis (Cmm), Erwinia carotovora subsp. carotovora (Ecc), Pepper mild mottle virus (PMMoV) and Tobacco mild green mosaic virus (TMGMV) in pepper and tomato seeds. Most of pepper and tomato bacterial and virus diseases are responsible for germination and growth obstruction. PCR with arbitral primers: selection of specific primers, performance of PCR with specific primers and determination of the threshold level for pathogens detection. To detect simultaneously the Xcv, Cmm, Ecc, PMMoV and TMGMV in pepper and tomato seeds, five pairs (Cmm-F/R, Ecc-F/R, Xcv-F/R, PMMoV-F/R, TMGMV-F/R) of specific primer were synthesized by primer-blast program. The multiplex PCR for the five pathogens in pepper and tomato seeds could detect specially without interference among primers and/or cDNA of plant seeds and other plant pathogens. The PCR result for pathogen detection using 20 commercial pepper and 10 tomato seed samples, Ecc was detected from 4 pepper and 2 tomato seed samples, PMMoV was detected from 1 pepper seed sample, and PMMoV and TMGMV were simultaneously detected from 1 pepper seed sample.