gebhart/patrepeval huggingface dataset:
Time-of-flight in Wireless Networks as Information Source for Positioning (2011)

The broad prevalence of mobile communication devices opens new business opportunities, including very diverse location based services. The required determination of the position of the devices is a big technical challenge. While GPS is a system for outdoor areas, there is no generally accepted solution for indoor areas. This dissertation introduces a new method that is particularly useful for indoor areas and uses the time of flight of a wireless signal. A significant advantage of the work presented in this thesis is the high time resolution for the signal time of flight measurement through which a very accurate location is achieved using commercial-off-the-shelf hardware. In addition, novel algorithms for the processing of the measurements and for calculating the 2D/3D position as well as three example implementations on different base technologies for wireless communications are presented.
Micromachined Millimeter-wave Ridge Waveguide Filter with Embedded MEMS Tuning Elements (2006)

This paper demonstrates the feasibility of constructing micromachined 3-dimensional ridge waveguide filters with built-in tuning elements. The objective of the tuning elements is to fine tune the filter in order to compensate for the fabrication tolerance of the micromachining process. A novel micromachined ridge waveguide filter with a coplanar line input/output interface is proposed. The structure is analyzed both theoretically and experimentally. A 2-pole micromachined millimeter-wave filter with embedded MEMS actuators as tuning elements is designed, fabricated and tested to demonstrate the concept. At 24 GHz, the filter size is only 2mm times 4mm
Reaction of poly(vinyl chloride) with magnesium and grignard reagents (1969)

Abstract Reaction of poly(vinyl chloride) with magnesium under various conditions was attempted, but poly(vinyl chloride) did not react with magnesium. The reactions of poly(vinyl chloride) with benzylmagnesium chloride and allylmagnesium chloride as Grignard reagents were carried out in tetrahydrofuran at reflux temperature. It was found that the chlorine atoms in the poly(vinyl chloride) were replaced by benzyl and allyl groups by the coupling reaction, and a small amount of Grignard reagent of poly(vinyl chloride) was formed by the magnesium–halogen exchange reaction. The extent of the substitution increased with increasing reaction time and concentration of the Grignard reagent.
Exploration on the characteristics of cellulose microfibers from Palmyra palm fruits (2016)

To obtain cellulose microfibers from Palmyra palm fruit fibers, a new succession of specific chemical treatments including acidified chlorination, alkalization, and acid hydrolysis have been developed. Cellulose microfibers obtained were characterized by different techniques. The chemical analysis indicated an increase in α-cellulose content and decrease in lignin and hemicellulose for the cellulose microfibers over raw fibers. Fourier transform infrared and 13C NMR spectra confirmed the removal of non-cellulosic (lignin and hemicellulose) components after chemical treatments. The X-ray diffraction results revealed that the cellulose I was partly transformed into cellulose II by chemical treatments and the crystallinity index of cellulose microfibers was significantly increased as compared to raw fibers owing to removal of non-cellulosic components. Thermogravimetric analysis results demonstrated that the thermal stability was enhanced noticeably for cellulose microfibers than for the raw fibers. The scanning electron micrographs illustrated cleaner and rough surfaces for the cellulose microfibers when compared to those of raw fibers.
Basement membrane and its components on lymphocyte adhesion, migration, and proliferation (1992)

Abstract During inflammation and recirculation, lymphocytes migrate into tissues by traversing the capillary endothelium, a process known as extravasation. After crossing the endothelial cells, lymphocytes come into contact with the basement membrane, which is a specialized layer of extracellular matrix containing predominantly laminin, collagen type IV, entactin, and heparan sulfate proteoglycans. In tissue invasion by inflammatory cells and metastatic tumor cells, the basement membrane serves as a substratum for cell adhesion and migration. However, the role of basement membrane in lymphocyte extravasation remains unclear. In this study, we investigated the effect of basement membrane on lymphocyte adhesion, migration, and proliferation, using matrigel as a model for basement membrane. We observed that matrigel promotes both lymphocyte adhesion and migration, with entactin primarily responsible for promoting adhesion and laminin for promoting migration. In addition, activation of lymphocytes by anti-CD3 enhances their adhesion and migration on matrigel-coated substratum. We also observed that matrigel inhibits the proliferation of lymphocytes stimulated by Con A. Furthermore, we demonstrated that laminin is the matrigel component responsible for inhibiting lymphocyte proliferation. However, matrigel has no effect on the proliferation of lymphocytes stimulated by LPS. These results suggest that matrigel has different effects on lymphocyte subpopulations. In agreement with the results on proliferation, matrigel also inhibits the production of IL-2 by Con A-stimulated lymphocytes.
The writing order of modern Chinese character components (2013)

笔顺对于汉字的教学、排检和计算机信息处理等都具有举足轻重的作用。本文在前辈专家关于汉字笔顺表与汉字部件表研究的基础上，做了三方面的工作：1. 析国家现有两个部件规范，对比它们的异同；2.给出部件序，并做出说明；3.给出《现代常用部件及部件名称规范》完整的笔顺表。
Lasers (2005)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Yong Wang, Miguel A. Larotonda, Bradley M. Luther, David Alessi, Mark Berrill, Mario C. Marconi, Vyacheslav N. Shlyaptsev, Jorge J. Rocca, Pavel Polynkin, Alexander Polynkin, Masud Mansuripur, Jerome Moloney, and Nasser Peyghambarian, "Lasers," Optics & Photonics News 16(12), 26-27 (2005) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
A <i>Zoogloea</i> sp. associated with blooms of <i>Anabaena flos-aquae</i> (1978)

Bacteria were found attached to the heterocysts of Aphanizomenon flos-aquae and embedded within the mucilage of both anabaena flos-aquae and Microcystis aeruginosa in freshwater plankton. Electron microscopy of thin sections preceding the peak of an Anabaena flos-aquae bloom showed that the density of bacterial cells was 7.4 X 10(5) cells/ml in the planktonic macroenvironment and 2.6 X 10(11) cells/ml within the microenvironment of cyanobacterial mucilage. The bacteria occurred in aggregates and isolation required that these be dispersed by homogenizing at 50 000 rpm with glass beads. This procedure yielded a single bacterial isolate from blooms of Anabaena flos-aquae during 2 consecutive years. The isolate was flagellated, catalase- and oxidase-positive. Gram-negative, and rod-shaped to pleomorphic. Observation that the isolate required a pH greater than 8 for consistent growth, could not grow alone on liquid media but could grow alone on the corresponding solid media, could grow in liquid media only in the presence of Anabaena, formed tough mucilagenous colonies on solid media only in the presence of Anabaena extract, and rapidly assimilated but did not respire extracellular 14C-labelled organic matter produced by Anabaena suggested that the occurrence of the bacterium in cyanobacterial mucilage was not coincidental but reflected an obligatory bacterial requirement for the biological or physicochemical microenvironment of the mucilage. The bacterial isolate occurred in three growth forms. Either as a planktonic swarmer cell (which showed a positive chemotactic response to the cyanobacterium) embedded in cyanobacterial mucilage, or embedded in its own mucilage derived, in part, from a low molecular weight (below 1300) carbohydrate secreted by the cyanobacterium. These cultural, biochemical, and ecological characteristics suggest that the isolate is a new species in the genus Zoogloea and of potential importance in phytoplankton ecology.
Mass-spectrometric studies of vitreous As2S3 (2011)

An analyze of vitreous As2S3 network structure models and photoinduced change of the structure is done in this paper. Is concluded that the interpretations of the results are not equivocal. Application of mass spectrometry, although it is an indirect method, contribute to the identification of main particles created during the evaporation of As2S3 glass in vacuum. As was established, the As4S3, As4S4, As4S5, As2S3, As2S4, As2S5, As2S6 molecular units and the As3S4, As3S3, As3S2, As3S, As, AsS2, As2S, As3S2, As2S2, S2, As, As2, As3 free radicals exist in the gas phase. The clusters like As10S15 can be created during the deposition on the substrate. Clusters are characterized by a different spatial structure with the same ratio of As/S atoms of 2:3. This particularity can explain the deposition of thin As2S3 films with different optical properties.
Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ<sub>1–42</sub>) to Aβ<sub>1–40</sub>, and Its Inhibition Enhances Brain Aβ Deposition (2007)

The abnormal deposition of the amyloid beta-protein (Abeta) in the brain appears crucial to the pathogenesis of Alzheimer's disease (AD). Recent studies have suggested that highly amyloidogenic Abeta(1-42) is a cause of neuronal damage leading to AD pathogenesis and that monomeric Abeta(1-40) has less neurotoxicity than Abeta(1-42). We found that mouse and human brain homogenates exhibit an enzyme activity converting Abeta(1-42) to Abeta(1-40) and that the major part of this converting activity is mediated by the angiotensin-converting enzyme (ACE). Purified human ACE converts Abeta(1-42) to Abeta(1-40) as well as decreases Abeta(1-42)/Abeta(1-40) ratio and degrades Abeta(1-42) and Abeta(1-40). Importantly, the treatment of Tg2576 mice with an ACE inhibitor, captopril, promotes predominant Abeta(1-42) deposition in the brain, suggesting that ACE regulates Abeta(1-42)/Abeta(1-40) ratio in vivo by converting secreted Abeta(1-42) to Abeta(1-40) and degrading Abetas. The upregulation of ACE activity can be a novel therapeutic strategy for AD.
691. The conversion of sucrose into pyridazine derivatives. Part XII. The stability of tetrahydro-6-ketopyridazine and 6-pyridazone derivatives towards acidic reagents (1950)

W. G. Overend and L. F. Wiggins, J. Chem. Soc., 1950, 3508 DOI: 10.1039/JR9500003508
QoS Control Mechanism Based on Real-Time Measurement of Elephant Flows (2007)

This proposes a scalable QoS control scheme, called Elephant Flow Control Scheme (EFCS) for high-speed large-capacity networks; it controls congestion and provides appropriate bandwidth to normal users' flows by controlling just the elephant flows. EFCS introduces a sampling packet threshold and drops packets considering flow size. EFCS also adopts a compensation parameter to control elephant flows to an appropriate level. Numerical results show that the sampling threshold increases control accuracy by 20% while reducing the amount of memory needed for packet sampling by 60% amount of memory by packet sampling; the elephant flows are controlled as intended by the compensation parameter. As a result, EFCS provides sufficient bandwidth to normal TCP flows in a scalable manner.
Overcoming Immune Evasion in Melanoma (2020)

Melanoma is the most aggressive and dangerous form of skin cancer that develops from transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is "curable" at this stage. However, after metastasis, it is difficult to treat and the five-year survival is only 25%. In recent years, a better understanding of the etiology of melanoma and its progression has made it possible for the development of targeted therapeutics, such as vemurafenib and immunotherapies, to treat advanced melanomas. In this review, we focus on the molecular mechanisms that mediate melanoma development and progression, with a special focus on the immune evasion strategies utilized by melanomas, to evade host immune surveillances. The proposed mechanism of action and the roles of immunotherapeutic agents, ipilimumab, nivolumab, pembrolizumab, and atezolizumab, adoptive T- cell therapy plus T-VEC in the treatment of advanced melanoma are discussed. In this review, we implore that a better understanding of the steps that mediate melanoma onset and progression, immune evasion strategies exploited by these tumor cells, and the identification of biomarkers to predict treatment response are critical in the design of improved strategies to improve clinical outcomes for patients with this deadly disease.
PERMANENT AND SPECIFIC TRANSPLANTATION TOLERANCE INDUCED BY A NONMYELOABLATIVE TREATMENT TO A WIDE VARIETY OF ALLOGENEIC TISSUES (1997)

The long-term success of organ transplantation is limited by complications resulting from consistent nonspecific immunosuppression. Induction of stable, donor-specific tolerance remains the main goal of transplantation immunology. In this article, a new, nonmyeloablative method is described for induction of transplantation tolerance to fully mismatched bone marrow cells (BMC), bone marrow stromal precursors, heart muscle, and skin allografts. The method is based on pretransplant conditioning with no postgraft immunosuppression, and consists of a short course (six daily fractions of 200 cGy) of total lymphoid irradiation (sTLI), followed by selective elimination of donor-specific alloreactive cells of the host escaping low-dose sTLI. Donor-specific alloreactive cells were activated by intravenous inoculation with a high dose of donor BMC (3×107 cells) 1 day after sTLI, and eliminated by a single intraperitoneal dose (200 mg/kg) of cyclophosphamide given 1 day after cell transfer. Infusion of a low number of T cell-depleted BMC (3×106 cells) after tolerogenic preconditioning converted recipients to stable mixed chimeras free of graft-versus-host disease. The same treatment provided long-lasting acceptance of heterotopically transplanted allografts of the heart muscle and of the stromal precursors to the hematopoietic microenvironment. This treatment also led to acceptance and life-long survival of full-thickness donor skin allografts. However, skin allografts survived only in mice that received donor T cell-depleted BMC after cyclophosphamide and had 20-50% donor cells in the blood. Our results suggest that after sTLI, additional selective clonal deletion of residual host cells induces a state of long-lasting specific tolerance to a wide variety of donor-derived tissues.
SMS-30: Fabrication of Highly Reliable Advanced Grid Structure(SMS-V: SMART MATERIALS AND STRUCTURES, NDE) (2005)

anci eemputational ef ficieneyL The simulated results fbr damage grewth will be shown in the presentation as weil.
Nuclear Factor 1 Family Proteins Bind to the Silencer Element in the Rat Glutathione Transferase P Gene (1997)

We have previously identified a silencer region in the glutathione transferase P (GST-P) gene, of which the expression is completely repressed in liver of the rat. At least three trans-acting factors bind to multiple cis-elements in this region. Since GST-P silencer 4 (GSP4) is a dominant element in this silencer, we purified the GSP4 binding protein, called Silencer Factor A (SF-A). Purified SF-A was separated into several proteins on an SDS-polyacrylamide gel, and the amino acid sequences of four major components of SF-A were determined. The amino acid sequences of three fragments were identical to those of rat NF1-L, and that of the other fragment was the same as that of hamster NF1/Red1. It is known that nuclear factor 1 (NF1) family proteins are encoded by at least four independent genes in vertebrates, and NF1-L and NF1/Red1 are derived from different genes, NFI-A and NFI-B, respectively. The microsequencing of SF-A revealed that at least two types of NF1 existed in rat liver. Functional analysis by using GAL4-fusion protein in HepG2 cells revealed that NFI-A represented the transcription activity from human metallothionein IIA promoter. Our findings indicate that multiple forms of the NF1 family bind to the silencer region and contribute to the negative regulation of the GST-P gene expression.
Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice (2014)

Leukemia immunotherapy frequently does not meet expectation, one of the handicaps being tumor exosome (TEX)-promoted immunosuppression. We here asked, using the mouse myeloid leukemia WEHI3B and the renal cell carcinoma line RENCA, whether dendritic cell (DC) vaccination suffices to counterregulate TEX-induced immunosuppression and whether TEX could serve as tumor antigen for DC-loading. DC-vaccination significantly prolonged the survival time of WEHI3B-bearing mice, TEX-loaded DC (DC-TEX) being superior to lysate-loaded DC (DC-lys), even an excess of TEX not interfering with immune response induction. The superior response to DC-TEX was accompanied by an increase in WEHI3B-specific CD4+ T cells, evaluated by trogocytosis and proliferation. Similar findings accounted for DC loaded with RENCA TEX. TEX was efficiently taken-up by DC and TEX uptake supported CD11c, MHCII and IL12 upregulation in DC. Importantly, TEX was partly recruited into the MHCII-loading compartment such that "TEX" presentation time and recovery in T cells significantly exceeded that of tumor-lysate. Thus, TEX did not drive DC into a suppressive phenotype and were a superior antigen due to higher efficacy of TEX-presentation that is supported by prolonged persistence, preferential processing in the MHCII-loading compartment and pronounced trogocytosis by T helper cells. TEX is present in tumor patients' sera. TEX, recovered and enriched from patients' sera, might well provide an optimized, individual-specific antigen source for DC-loading and vaccination.
Einsatz und Auslegung statischer Mischer (1979)

Abstract Application and design of static mixers . Static mixers are units without, or only with fixed, internal fittings which effect the mixing of flowing materials with the aid of their kinetic energy. They are used for continuous homogenization and dispersion, for limitation of the residence time spectrum, and for raising heat and mass transfer in all areas of chemical engineering. Over 20 static mixers are presented, and compared with regard to pressure drop, mixing quality, energy consumption, and residence time and heat transfer behaviour. Important selection criteria are reported. Static mixers have the following advantages over dynamic mixers: use for a wide range of viscosities, narrow residence time spectrum, readily adaptable to existing pipe systems, frequently require no extra space (in‐line mixers), negligible maintainance and wear, low investment and operating costs.
Effects of metal-doped indium-tin-oxide buffer layers in organic light-emitting devices (2006)

Organic light-emitting devices were fabricated by using different metal (V, Zr, Hf)-doped indium-tin-oxide (ITO) buffer layers on an ITO anode. The metal-doped ITO buffer layers were 15nm thick with different metal concentrations. Both resistivity and work function of the ITO buffer layer were manipulated by these metal dopants. Different effects on the devices, such as reduced turn-on voltage, improved luminance, and enhanced current efficiency, were investigated. A low turn-on voltage was observed for devices with small work function and resistivity. The lowest turn-on voltage (3V) was found on a device with a V-doped ITO buffer layer. The devices usually have a similar current density (J)-voltage (V) characteristics, but not the luminance-J or the current efficiency-J characteristics when the ITO buffer layers have the same work function. The devices with the Hf-doped ITO buffer layers show the best luminance performance among those considered. At 100mA∕cm2, a luminance of 15,000cd∕m2, and a current efficiency of 15cd∕A have been achieved. The balance between the carrier concentration and the energy barrier for the hole injection is possibly responsible for such performance.
Viel Farbe aus wenig Licht: Mikrospektrometer (2002)

Das LIGA-Verfahren erlaubt die mikrosystemtechnische Herstellung von Mikrospektrometern für verschiedene Wellenlängenbereiche. Diese Mikrospektrometer sind kompakt, kostengünstig, brauchen keine aufwändige Justage und kommen ohne leistungsstarke Stromversorgung aus. Deshalb sind sie besonders für mobile Anwendungen geeignet. Die Mikrospektrometer erschließen auch völlig neue Einsatzgebiete. Ein Beispiel sind Anwendungen in der Medizintechnik, für die konventionelle Spektrometer zu groß und zu unflexibel sind.
Solar Energy and Building Physics Laboratory - Activity Report 2009 (2010)

LESO-PB
Dendritic Cells for Specific Cancer Immunotherapy (2001)

The characterization of tumor-associated antigens recognized by human T lymphocytes in a major histocompatibility complex (MHC)-restricted fashion has opened new possibilities for immunotherapeutic approaches to the treatment of human cancers. Dendritic cells (DC) are professional antigen presenting cells that are well suited to activate T cells toward various antigens, such as tumor-associated antigens, due to their potent costimulatory activity. The availability of large numbers of DC, generated either from hematopoietic progenitor cells or monocytes in vitro or isolated from peripheral blood, has profoundly changed pre-clinical research as well as the clinical evaluation of these cells. Accordingly, appropriately pulsed or transfected DC may be used for vaccination in the field of infectious diseases or tumor immunotherapy to induce antigen-specific T cell responses. These observations led to pilot clinical trials of DC vaccination for patients with cancer in order to investigate the feasibility, safety, as well as the immunologic and clinical effects of this approach. Initial clinical studies of human DC vaccines are generating encouraging preliminary results demonstrating induction of tumor-specific immune responses and tumor regression. Nevertheless, much work is still needed to address several variables that are critical for optimizing this approach and to determine the role of DC-based vaccines in tumor immunotherapy.
Fast Nonlinear Ion Transport via Field-Induced Hydrodynamic Slip in Sub-20-nm Hydrophilic Nanofluidic Transistors (2009)

Electrolyte transport through an array of 20 nm wide, 20 microm long SiO(2) nanofluidic transistors is described. At sufficiently low ionic strength, the Debye screening length exceeds the channel width, and ion transport is limited by the negatively charged channel surfaces. At source-drain biases >5 V, the current exhibits a sharp, nonlinear increase, with a 20-50-fold conductance enhancement. This behavior is attributed to a breakdown of the zero-slip condition. Implications for energy conversion devices are discussed.
In polymyalgia rheumatica serum prolactin is positively correlated with the number of typical symptoms but not with typical inflammatory markers (2002)

The number of symptoms in PMR patients was positively correlated with PRL, but PRL was not correlated with serum markers of inflammation. This indicates that PRL is not a pro-inflammatory stimulus in patients with PMR. The inter-relationship between PRL and symptoms or duration of morning stiffness may be more a sign of central nervous system involvement, as it can be observed in people with depressed mood or under psychological stress.