gebhart/patrepeval huggingface dataset:
Systemic Inflammatory Response in Cardiac Allograft Vasculopathy (2000)

Background —Response to immunologic and nonimmunologic injury has been reported to initiate the development of cardiac allograft vasculopathy (CAVD). Although histopathologic examinations reveal signs of focal inflammation, little is known about the systemic inflammatory response in this accelerated coronary syndrome. Methods and Results —Therefore, we investigated high-sensitive C-reactive protein (CRP) in a large cohort of heart transplant (HTX) recipients (n=102, 90 male, mean age 45.2±11.5 years, 6.1±3.3 years after HTX) in correlation with a progression of luminal obstruction as assessed by serial coronary angiography (defined as an increase of focal stenosis ≥30% or detection of a new lesion) after a mean interval of 1.8±1.0 years. Patients with signs of an acute rejection or infection were excluded. In the entire group, CRP levels ranged from 0.2 to 12.7 mg/L (mean 2.6±2.7 mg/L). Patients with progressive CAVD (n=35) presented with significantly higher levels of CRP (4.1±3.3 mg/L) than did those with a nonprogressive course (n=67) (1.8±1.9 mg/L, P =0.001). These observations were independent of the initial indication for HTX (atherosclerotic disorder versus cardiomyopathy, P =0.18) and the severity of CAVD at baseline examination ( P =0.12). Conclusions —Progressive cardiac allograft vasculopathy is accompanied by a systemic inflammatory reaction, which gives further insight into the pathogenesis of this coronary syndrome and may well serve as an indicator for patients at risk.
Urinary Tract Infections Accompanying Brucellosis (1939)

No AccessJournal of Urology1 Aug 1939Urinary Tract Infections Accompanying Brucellosis1 Anson L. Clark Anson L. ClarkAnson L. Clark More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)71513-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1939 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByKelalis P, Greene L and Weed L (2018) Brucellosis of the Urogenital Tract: A Mimic of TuberculosisJournal of Urology, VOL. 88, NO. 3, (347-353), Online publication date: 1-Sep-1962. Volume 42Issue 2August 1939Page: 249-256 Advertisement Copyright & Permissions© 1939 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Anson L. Clark More articles by this author Expand All Advertisement PDF DownloadLoading ...
Effects of High Energy Electron Irradiation on a Yttrium Barium(2) Copper(3) Oxygen(7-delta) High Temperature Superconductor (1991)

High quality, single crystalline, high-temperature superconductors were irradiated with 88.5 and 92.0 MeV electrons at various fluences to a maximum of 2.5+/- 0.5 x 10 to the 18th power electrons/sq cm. The samples were manufactured at the Texas Center for Superconductivity at the University of Houston and this experiment was in support of a much larger experiment investigating the effects of various irradiations on the critical current. By introducing artificial pinning centers, such as those produced by electron irradiation, in high-temperature superconductors, an applied magnetic flux can be effectively pinned and the current carrying capacity can be increased. By comparing the critical current density enhancement effects to the total atomic displacement damage, it is found that the enhancement depends heavily on the type and energy or radiation and on the beam direction with respect to the crystal. It was also found that a threshold defect-size for effective flux pinning exists. Cascade defects, 10-20 A and larger, are at least a thousand times more effective than point defects as pinning centers.
SHORT-TERM BRIDGE TO TRANSPLANT USING THE BVS 5000 VENTRICULAR ASSIST DEVICE. (2000)

Marelli, Daniel; Laks, Hillel; Moriguchi, Jaime; Fazio, Daniel; Meehan, Deborah; Talamo, Martin; Sadeghi, Ali; Esmailian, Fardad; Ardehali, Abbas Author Information
Amino acids and nitrate as signals for the regulation of nitrogen acquisition (2007)

The uptake of nitrogen (N) by roots is known to change with supply in a manner that suggests that the N status of plants is somehow sensed and can feedback to regulate this process. The most abundant source of N in soils for crops is nitrate. Uptake systems for nitrate, ammonium, and amino acids are present in the roots of most plants including crops. As nitrate is assimilated via conversion to nitrite, then ammonium into amino acids, it has been suggested that the internal pools of amino acids within plants may indicate nitrogen status by providing a signal that can regulate nitrate uptake by the plant. In support of this idea, both nitrate and ammonium influx and transporter transcript were shown to decrease in root tissue treated with exogenously applied amino acids. Several different amino acids have been tested for their effects on influx and transcription and glutamine was most effective. The feedback regulation occurs by changing the expression of transporters, but may also involve the post-translational modification of proteins. For example, some of the cytoplasmic enzymes responsible for nitrate assimilation are regulated by phosphorylation and binding of a 14-3-3 protein. The effects of treating plants with glutamine have been examined, first to identify the uptake of the amino acid and then to measure tissue nitrate reductase activity and cellular pools of nitrate. These results are reviewed in terms of feedback regulation and the putative cell sensing systems for N status including a possible specific role for cytosolic nitrate.
An Efficient Cross-Layer Based Flooding Algorithm with Retransmission Node Selection for Wireless Sensor Networks (2008)

In this paper, we propose a flooding algorithm with retransmission node selection (FARNS) for wireless sensor networks. It is an efficient cross-layer based flooding technique to solve a broadcast storm problem that is produced by simple flooding of nodes in wireless sensor networks. FARNS can decrease waste of unnecessary energy by controlling retransmission action of whole network nodes by deciding retransmission candidate nodes that are selected by identifier information of neighbor nodes in MAC and distance with neighborhood nodes through received signal strength information in PHY. In simulation results show that FARNS has excellent performance than the other flooding schemes in terms of broadcast forwarding ratio, broadcast delivery ratio, and the number of redundancy packets and overhead.
Quantifying changes in RPE and choroidal vasculature in eyes with age-related macular degeneration. (2002)

In these eyes with GA, RPE atrophy was more severe than loss of choriocapillaris. Surviving choriocapillaris in areas with complete RPE loss was highly constricted. The association of surviving RPE cells with CNV suggests that RPE cells may furnish a stimulus for new vessel formation or stabilization.
The role of torsinA in dystonia (2010)

DYT1 dystonia is an autosomal-dominant movement disorder, characterised by early onset of involuntary sustained muscle contractions. It is caused by a 3-bp deletion in the DYT1 gene, which results in the deletion of a single glutamate residue in the C-terminus of the protein torsinA. TorsinA is a member of the AAA-ATPase family of; chaperones with multiple functions in the cell. There is no evidence of neurodegeneration in DYT1 dystonia, which suggests that mutant torsinA leads to functional neuronal abnormalities leading to dystonic movements. In the recent years, different functional roles have been attributed to torsinA, including being a component of the cytoskeleton and the nuclear envelope, and involvement in the secretory pathway and synaptic vesicle machinery. The aim of this review is to summarise these findings and the different models proposed, which have contributed to our current understanding of the function of torsinA.
Tests of a practical visible-NIR imaging Fourier transform spectrometer for biological and chemical fluorescence emission measurements (2009)

An imaging Fourier transform spectrometer (IFTS) designed for fluorescence emission measurements is reported. The spectral range extension from NIR to visible of the system is realized by using a simple and low-cost optical beam-folding position-tracking technique. Spectral resolution as high as 9.78cm(-1)(0.4nm at 632.8nm) and maximum image resolution up to 300x300 pixels are proved by the system tests on its optical performances. Imaging fluorescence spectra acquisition of quantum dot clusters and single 200nm diameter fluorescent beads have demonstrated the system's potential for high throughput imaging spectroscopic measurements of fluorescent biological and chemical samples.
Improved homogeneity of the transmit field by simultaneous transmission with phased array and volume coil (2010)

We have demonstrated the feasibility of using simultaneous transmission with human head-sized volume coils and CRC phased arrays to improve homogeneity of the transmit RF B(1) field for high-field MRI systems.
C. Van Woodward, 1908–1999 (2000)

Journal Article C. Van Woodward, 1908–1999 Get access James Green James Green Search for other works by this author on: Oxford Academic Google Scholar History Workshop Journal, Volume 50, Issue 1, AUTUMN 2000, Pages 303–306, https://doi.org/10.1093/hwj/2000.50.303 Published: 01 October 2000
Building decision trees for characteristic ellipsoid method to monitor power system transient behaviors (2010)

This paper presents the idea and initial results of building decision trees (DTs) for detecting and identifying various transient dynamic events using the characteristic ellipsoid method. In this paper, the objective is to determine fault types, fault locations and clearance times in the system using DTs based on ellipsoids surrounding system transient responses in the system operating parameter space. The New England 10-machine 39-bus system is used to generate a sufficiently large number of transient events in different system configurations. Comprehensive transient simulations considering three fault types, two different fault clearance times and various fault locations were conducted in the study. Bus voltage magnitudes and monitored reactive and active power flows are recorded as the phasor measurements to calculate characteristic ellipsoids whose volume, eccentricity, center and projection of the longest axis on the parameter space coordinates are used as indices to build decision trees. The DTs performance is tested and compared for different sets of phasor measurement units (PMUs) locations. The results demonstrate that, depending on the number and location of PMUs in the model, the proposed approach is capable to detect the fault type, location, and clearance time in up to 99% of the cases which are not included in the training set used to build the DT.
Corrigendum to “Automated Feature Extraction in Brain Tumor by Magnetic Resonance Imaging Using Gaussian Mixture Models” (2017)

[This corrects the article DOI: 10.1155/2015/868031.].
Geometric Invariants for Facial Feature Tracking with 3D TOF Cameras (2007)

This paper presents a very simple feature-based nose detector in combined range and amplitude data obtained by a 3D time-of-flight camera. The robust localization of image attributes, such as the nose, can be used for accurate object tracking. We use geometric features that are related to the intrinsic dimensionality of surfaces. To find a nose in the image, the features are computed per pixel; pixels whose feature values lie inside a certain bounding box in feature space are classified as nose pixels, and all other pixels are classified as non-nose pixels. The extent of the bounding box is learned on a labeled training set. Despite its simplicity this procedure generalizes well, that is, a bounding box determined for one group of subjects accurately detects noses of other subjects. The performance of the detector is demonstrated by robustly identifying the nose of a person in a wide range of head orientations. An important result is that the combination of both range and amplitude data dramatically improves the accuracy in comparison to the use of a single type of data. This is reflected in the equal error rates (EER) obtained on a database of head poses. Using only the range data, we detect noses with an EER of 0.66. Results on the amplitude data are slightly better with an EER of 0.42. The combination of both types of data yields a substantially improved EER of 0.03.
Ice Thickness Measurement Method for Thermal Energy Storage Unit (2011)

The aim of this study is to develop a measurement method to determine the solidification front in a thermal energy storage unit. The electrical conductivity of a phase change material (PCM) changes dramatically in solidification/melting process and the proposed measurement method is based on observation of electrical conductivity of PCM. This system utilizes a microprocessor and a multiplexer unit to observe medium via multiple nodes. The experimental results show that the accuracy of this method is nearly 3%, in comparison with the traditional photography method. The most important advantages of this method are elimination of the heat gain, caused by opening a cover in the insulation at specific time periods, compared to the with photography method and ease of observation of solidification fronts electronically which results wider application area where photography method cannot be exploited
Dimorphs of sucrose (2007)

Re-crystallized sucrose (RS) solids grown from the methanol-water solution at 60°C exhibited two endothermic peaks at 150°C and 189°C by differential scanning calorimetry (DSC) at 10°C/min whereas commercial sucrose (CS) displayed only one endothermic peak at 190°C. However, the water content of RS of only 0.03 w/w % measured by Karl Fischer (KF) titrimetry was surprisingly less than the one of CS of 0.49 w/w %. Obviously, the inclusion of water was not a satisfying explanation for the endotherm at 150°C observed for RS. Both powder X-ray diffraction (PXRD) and single-crystal X-ray diffraction (SXD) further suggested the variations of the thermal behavior between RS and CS could be due to the presence of conformational polymorphs about the glycosidic linkage. The two conformational polymorphs were enantiotropically related and gave different solubility curves in water and dissolution profiles for formulated acetaminophen. These phenomena has raised an important issue on the quality control of sucrose and their manufacturing protocol if sucrose was to be developed into added functionality excipients for pharmaceutical formulations in the future.
Global Mortality Attributable to Aircraft Cruise Emissions (2010)

Aircraft emissions impact human health though degradation of air quality. The majority of previous analyses of air quality impacts from aviation have considered only landing and takeoff emissions. We show that aircraft cruise emissions impact human health over a hemispheric scale and provide the first estimate of premature mortalities attributable to aircraft emissions globally. We estimate ∼8000 premature mortalities per year are attributable to aircraft cruise emissions. This represents ∼80% of the total impact of aviation (where the total includes the effects of landing and takeoff emissions), and ∼1% of air quality-related premature mortalities from all sources. However, we note that the impact of landing and takeoff emissions is likely to be under-resolved. Secondary H<sub>2</sub>SO<sub>4</sub>−HNO<sub>3</sub>−NH<sub>3</sub> aerosols are found to dominate mortality impacts. Due to the altitude and region of the atmosphere at which aircraft emissions are deposited, the extent of transboundary air pollution is particularly strong. For example, we describe how strong zonal westerly winds aloft, the mean meridional circulation around 30−60°N, interaction of aircraft-attributable aerosol precursors with background ammonia, and high population densities in combination give rise to an estimated ∼3500 premature mortalities per year in China and India combined, despite their relatively small current share of aircraft emissions. Subsidence of aviation-attributable aerosol and aerosol precursors occurs predominantly around the dry subtropical ridge, which results in reduced wet removal of aviation-attributable aerosol. It is also found that aircraft NO<sub><i>x</i></sub> emissions serve to increase oxidation of nonaviation SO<sub>2</sub>, thereby further increasing the air quality impacts of aviation. We recommend that cruise emissions be explicitly considered in the development of policies, technologies and operational procedures designed to mitigate the air quality impacts of air transportation.
Characterization of electrochromic nickel oxide thin films prepared by anodic deposition (1992)

Nickel oxide (NiOx) thin films have been prepared on transparent conducting indium tin oxide (ITO) substrates by anodic deposition from a nickel ammine complex solution. Electrochromic (EC) behaviour of these films was observed in a borate buffer solution at pH 10 in the potential range 0–1 V vs. Ag/AgCl; an as-prepared film (PF) was cathodically reduced to a colourless form (RF) and oxidized to a brown form (OF) by anodic polarization. Characterization of these films by low-angle incident X-ray diffraction and X-ray photoelectron spectroscopy with argon-ion (Ar+) etching revealed that the EC properties are based on the electrolytic transformation of the NiOx structure between β-NiOOH and β-Ni(OH)2, i.e. involving the redox reaction Ni3++ e ⇄ Ni2+.
<i>Ab Initio</i> Design of Potent Anti-MRSA Peptides Based on Database Filtering Technology (2012)

To meet the challenge of antibiotic resistance worldwide, a new generation of antimicrobials must be developed. This communication demonstrates ab initio design of potent peptides against methicillin-resistant Staphylococcus aureus (MRSA). Our idea is that the peptide is very likely to be active when the most probable parameters are utilized in each step of the design. We derived the most probable parameters (e.g., amino acid composition, peptide hydrophobic content, and net charge) from the antimicrobial peptide database by developing a database filtering technology (DFT). Different from classic cationic antimicrobial peptides usually with high cationicity, DFTamP1, the first anti-MRSA peptide designed using this technology, is a short peptide with high hydrophobicity but low cationicity. Such a molecular design made the peptide highly potent. Indeed, the peptide caused bacterial surface damage and killed community-associated MRSA USA300 in 60 min. Structural determination of DFTamP1 by NMR spectroscopy revealed a broad hydrophobic surface, providing a basis for its potency against MRSA known to deploy positively charged moieties on the surface as a mechanism for resistance. Our ab initio design combined with database screening led to yet another peptide with enhanced potency. Because of the simple composition, short length, stability to proteases, and membrane targeting, the designed peptides are attractive leads for developing novel anti-MRSA therapeutics. Our database-derived design concept can be applied to the design of peptide mimicries to combat MRSA as well.
Parallel computing in seismic data processing (1993)

Commercial seismic data processing has traditionally been at the leading edge of computer developments. The industry’s hunger for computing power resulted in the early widespread use of processing accelerators and vector supercomputers. Today, the pressures are arguably more demanding.
Two Proton Pump Interactors Identified from a Direct Phosphorylation Screening of a Rice cDNA Library by Using a Recombinant BRI1 Receptor Kinase (2004)

A direct phosphorylation screening of a rice cDNA library resulted in isolation of 35 BIP clones encoding brassinosteroid receptor kinase (BRI1)-interacting proteins. Among the candidate substrates for BRI1, two clones were found to encode similar proton pump interactor proteins homologous to Arabidopsis PPI1, which was reported to interact with a regulatory region of plasma membrane H+-ATPase. The rice proton pump interactors BIP103 and BIP131 contained 627 and 621 amino acids, respectively, with carboxyl-terminal hydrophobic region characteristic of tail-anchored proteins. Northern blotting analysis indicated that mRNAs for both interactors increased significantly after brassinolide treatment of lamina joint cells, which are especially sensitive to exogenous brassinosteroids.
Olefindiazoniumsalze (1975)

Abstract Die Umsetzung der p ‐Toluolsulfonylhydrazone 7 von α‐Halogenaldehyden und α‐Halogenketonen mit Lewis‐Säuren wie Zinntetrachlorid, Aluminiumchlorid oder Antimonpentachlorid führt über eine Azoolefin‐Zwischenstufe 8 zu Olefindiazoniumsalzen (z. B. 9 ). Das 2,2‐Di‐chloräthylen‐1‐diazonium‐hexachloroantimonat ( 6a ) geht auch aus der Reaktion des 2,2‐Dichlorvinylisocyanats ( 5 ) mit dem entsprechenden Nitrosylsalz hervor. Mit Ausnahme der besonders resonanzstabilisierten Verbindungen 22 und 23 besitzen nur solche Alkendiazoniumionen eine für die Isolierung ausreichende thermische Stabilität, die bei der Stickstoff‐abspaltung energiereiche Vinylkationen bilden. Exemplarisch für den stark elektrophilen Charakter der Olefindiazoniumsalze sind die mit Anisol und Methanol schrittweise durch‐geführten Umwandlungen von 6a in das 2‐Chlor‐2‐( p ‐methoxyphenyl)äthylen‐1‐diazonium‐und 2‐Methoxy‐2‐( p ‐methoxyphenyl)äthylen‐1‐diazonium‐hexachloroantimonat ( 25 und 26 ). Durch den Einfluß elektronenspendender Substituenten in der 2‐Stellung eines Äthylen‐diazoniumions läßt sich der Grad der NN‐Dreifachbindung so weit verringern, daß er dem des Diazoessigesters gleichkommt.
Analysis of mononuclear cell surfaces with fluoresceinated staphylococcal protein A complexed with IgG antibody of heat-aggregated gamma-globulin. (1976)

Fluorescein-conjugated staphylococcal protein A (SPA) was complexed with either: 1) heat-aggregated IgG, 2) B cell specific antibody, or 3) T cell specific antibody and then used for an immunofluorescent analysis of mononuclear cell surfaces. Cellular Fc receptors failed to recognize the Fc region of aggregated IgG that had been blocked by SPA. Moreover, fluoresceinated SPA that had been complexed either with anti-Fab (B-cell specific) or T cell-specific antisera prevented the nonspecific binding of these reagents to the IgG-Fc receptors on mononuclear cells, thereby permitting the latter to be properly identified as B or T lymphocytes. In addition, when unconjugated SPA was added to presensitized target cells in a test for antibody-dependent cell-mediated cytotoxicity, cytolysis was abrogated.
The role of cortisol suppression on craving for and satisfaction from nicotine in high and low impulsive subjects (2002)

The rewarding properties of drug self-administration have been shown to depend on mesolimbic dopamine release but also on the availability of corticosterone, as shown in rats. Since this became particularly evident when tested in rat strains bred for high (HR) and low (LR) reactivity to novel stimuli, the role of cortisol and personality in drug craving was investigated in 60 male nicotine-deprived smokers divided according to questionnaire scores into high and low impulsives, a dimension considered to represent HR/LR rats. They either received the peripheral cortisol blocker metyrapone (MET) or the centrally blocking substance dexamethasone (DEX) or placebo (n=20 each) and were then allowed to smoke. MET more than DEX reduced craving for cigarettes during deprivation. This was only observed in low impulsives while high impulsives developed low craving unmodified by blockade of cortisol. Satisfaction from smoking was less achieved with DEX than with MET and not modified by impulsivity. Differences between MET and DEX in influencing craving during deprivation and satisfaction from smoking were discussed on the basis of different glucocorticoid receptors. The mineralocorticoid receptor (MR) seems to be the 'turn on switch' and the glucocorticoid receptor (GR) the 'turn off switch' in mediating the rewarding properties of dopamine in drug self-administration.