gebhart/patrepeval huggingface dataset:
Rapid typing of STRs in the human genome by HyBeacon® melting (2008)

A new method based on DNA melting has been developed for the rapid analysis of STRs in the human genome. The system is based on homogeneous PCR followed by fluorescence melting analysis and utilises a HyBeacon® probe combined with a PCR primer-blocker oligonucleotide. The use of blockers of different length permits identification of the full range of common D16S539 repeats enabling detection of 99.8% of known alleles. The interrogation of STRs can be carried out on standard genetic analysis platforms and could be applied to other loci to form the basis of a bespoke high-throughput system for use in forensic analysis, particularly as fluorescent genetic analysis platforms are now available for high-resolution melting. This methodology may be suitable for rapid forensic DNA analysis at the point-of-arrest or in a custody suite where it is important to identify an individual from a small group of suspects/detainees.
Statistical pattern recognition with neural networks: benchmarking studies. (1988)

Successful recognition of natural signals, e.g., speech recognition, requires substantial statistical pattern recognition capabilities. This is at odds with the fact that the bulk of work on applying neural networks to pattern recognition has concentrated on non-statistical problems. Three basic types of neural-like networks (Backpropagation network, Boltzmann machine, and Learning Vector Qumtization), were applied in this work to two representative artificial statistical pattern recognition tasks, each with varying dimensionality. The performance of each network's different approach to solving the tasks was evaluated and compared, both to the performance of the other two networks, and to the theoretical limit. The Learning Vector Quantization was further benchmarked against the parametric Bayes classifier and the k-nearestneighbor classifier using natural speech data. A novel Learning Vector Quantization classifier (LVQ2) is introduced the first time in this work.
Synthese und Reaktionsverhalten von Übergangsmetallkomplexen sowie deren Verwendung in der Homogenen Katalyse und Metallabscheidung (2008)

Die vorliegende Arbeit beschäftigt sich mit der Synthese von Kupfer(I)- und Silber(I)- Carboxylaten der Form [MO2CR] und [LmMO2CR] (L = 2-Elektronen-Donorligand; m = 1, 2, 3; M = Cu, Ag; R = org. Rest). Die Verwendung dieser Komplexe zur Abscheidung von Metallen wird anhand ausgewählter Verbindungen mittels unterschiedlicher Abscheideprozesse beschrieben. Die Darstellung von neuartigen Ethinylferrocen-funktionalisierten Phosphanen und deren Koordinationsverhalten in Bezug auf Übergangsmetalle ebenfalls Thema der Arbeit. Das elektrochemische Verhalten wurde mittels Cyclovoltammetrie näher untersucht und der Einsatz von Ethinylferrocen-funktionalisierten Phosphan-Palladium(II)-Komplexen in der Suzuki- Miyaura- und Heck-Mizoroki-Kreuzkupplungsreaktion getestet. 2,2’-Bipyrimidin als Chelat- bzw. als μ-1,2,3,4-verbrückender Ligand ist in der Lage heterotetrametallische Übergangsmetallkomplexe mit z. B. Platin(II)-Bisalkinyleinheiten zu bilden. An ausgewählten Verbindungen werden die elektrochemischen Eigenschaften vorgestellt. Weiterer Bestandteil dieser Arbeit ist die Synthese und Charakterisierung von heterobimetallischen Komplexen aufgegriffen, in welchen frühe und späte Übergangsmetalle über eine Fulvalenideinheit verknüpft sind.
Log Management In Cloud Through Big Data (2016)

In the recent days Cloud computing has become a buzz word that has planted itself in the next cohort of IT industry, performing huge-scale and complex computing. As cloud technology continues to progress, huge growth in data generated through cloud computing has been noticed. A vast part of that data is machine originated log data; it is generated at each layer in  cloud technology environment. Logs are used for  troubleshooting, security, debugging, etc.,It is argued that cloud computing is in need of a new methods for recording, managing, storing, analyzing the log data that is resulted by the cloud infrastructure, based on big data technologies.
Reduced-order averaged modeling of active-clamp converters (2006)

Reduced-order averaged modeling and analysis of soft-switching dc-dc converters employing active clamping techniques are presented in this paper. A general modeling method based on time-scale separation of converter state variables is used to develop large-signal averaged models that accurately represent the converter dynamics up to half the switching frequency. The fast-changing resonant variables of the active clamping circuits are eliminated in the modeling process, resulting in reduced-order models that are much simpler than existing full-order models. A method is also presented to account for the effects of switching-frequency ripple on converter dynamics in the low-frequency region. A transformer-coupled active-clamp single-ended primary inductance converter (SEPIC) is studied in detail to demonstrate the application of the method. Numerical simulation and experimental measurement of frequency responses of a experimental SEPIC converter are presented to validate the developed models. Additionally, an active-clamp flyback converter is briefly studied to demonstrate the general applicability of the method to other active-clamp converter topologies.
Aspergillus Specific IgE Estimation By Radioallergosorbent Techniqe (Rast) In Obstructive Airways Disease At Agra (1986)

Countries from South-East Europe (SEE), Central and Eastern Europe (CEE) and Newly Independent States (NIS) are in the process of harmonization with European environmental noise legislation. However, research work on noise and health was performed in some countries independently of harmonization process of adoption and implementation of legislation for environmental noise. Aim of this review is to summarize available evidence for noise induced sleep disturbance in population of CEE, SEE and NIS countries and to give directions for further research work in this field. After a systematic search through accessible electronic databases, conference proceedings, PhD thesis, national reports and scientific journals in English and non-English language, we decided to include six papers and one PhD thesis in this review: One paper from former Yugoslavia, one paper from Slovakia, one paper from Lithuania, two papers from Serbia and one paper, as also one PhD thesis from The Former Yugoslav Republic of Macedonia. Noise exposure assessment focused on road traffic noise was mainly performed with objective noise measurements, but also with noise mapping in case of Lithuanian study. Sleep disturbance was assessed with the questionnaire based surveys and was assumed from dose-effect relationship between night-time noise indicator (Lnight ) for road traffic noise and sleep disturbance (for Lithuanian study). Although research evidence on noise and sleep disturbance show to be sufficient for establishing dose response curves for sleep disturbance in countries where studies were performed, further research is needed with particular attention to vulnerable groups, other noise sources, development of laboratory research work and common methodology in assessment of burden of diseases from environmental noise.
Energy efficiency of distributed energy system based on central heating network (2017)

On the basis of existing urban central heating network, a distributed energy system is put forward. The objective function method is adopted to calculate the operating cost of heating season, the energy quality coefficient is used to evaluate the quality of different kinds of energy, and the exergy efficiency of heat exchange is analyzed to measure the energy utilization level. Operation cost and energy efficiency of the distributed energy system and conventional gas peak-shaving system are studied and compared. Results indicate that the distributed energy system based on the heating network can make full use of the waste heat generated by gas turbine, improve the exergy efficiency of heat exchange and decrease the fuel consumption.
Heterocycle Formation via Palladium-Catalyzed Intramolecular Oxidative C−H Bond Functionalization: An Efficient Strategy for the Synthesis of 2-Aminobenzothiazoles (2009)

N-arylthioureas are converted to 2-aminobenzothiazoles via intramolecular C-S bond formation/C-H functionalization utilizing an unusual cocatalytic Pd(PPh(3))(4)/MnO(2) system under an oxygen atmosphere at 80 degrees C. This method eliminates the need for an ortho-halo substituted precursor, instead achieving direct functionalization of the ortho-aryl C-H bond. Mechanistic observations, including a large intramolecular primary kinetic isotope effect of 5.9, reveal a reaction pathway inconsistent with an electrophilic palladation mechanism.
Graphene oxide and functionalized multi walled carbon nanotubes as epoxy curing agents: a novel synthetic approach to nanocomposites containing active nanostructured fillers (2014)

A novel synthetic approach is developed wherein graphene oxide and oxidized multiwalled carbon nanotubes are used as curing agents to induce cross-linking of an epoxy resin, thereby yielding a nanostructured epoxy composite with excellent dispersion of the carbon nanomaterials. This method allows for incorporation of up to 50 wt% of carbon nanomaterials within the polymeric matrix. The combination of covalent bonding and π–π interactions ensure excellent dispersibility of the nanomaterials within the polymeric matrix. These nanocomposites offer an alternative to the hazardous high-temperature fluorination and amine curing reactions that are usually required to formulate epoxy composite systems. Structural, mechanical, and morphological characterization of the composite material confirms the distribution, integrity, and potential to resist corrosion on a steel surface while also indicating the excellent adhesion and flexibility of the nanocomposite coatings.
Digital device manuals for the management of ConnectedSpaces (2002)

An increasing number of devices that can be monitored and controlled via the Internet have begun to appear in the commercial domain. Health care devices, such as heart rate monitors and dialysis machines, home and other security devices, and climate control devices, are a few of the device types that are increasingly becoming connectable to the Internet. When many such devices come together we say they form a ConnectedSpace. Many nonfunctional behavioral constraints, such as those related to safety, security, privacy, and fault tolerance, may be imposed on a ConnectedSpace. These constraints may be monitored and enforced by a centralized or distributed management algorithm. Various approaches may be used for enforcing the constraints. Digital device manuals are envisioned to capture the generic information required by the different approaches to monitor and enforce the constraints.
Physical modeling of beneficial dynamic floating-body effects in non-fully depleted SOI CMOS circuits (2002)

The floating-body configuration is desirable in scaled SOI CMOS technology because of area efficacy. Unfortunately it portends various problems, one of which is the premature parasitic-BJT breakdown that occurs in both fully depleted (FD) and non-fully depleted (NFD) SOI MOSFETs. In the NFD device, other floating-body effects, some of which can be beneficial, are apparent at drain-source voltages below the breakdown because of the sensitivity of threshold voltage to the body-source bias. This bias, which can be forward or reverse in dynamic operation of the MOSFET, is due to positive or negative excess majority-carrier densities in the floating body. In this paper, we present a physical model for the NFD/SOI MOSFET and use it in a circuit simulator (SOISPICE) to identify and assess beneficial floating-body effects in dynamic operation of scaled CMOS digital circuits.
Progress in dynamic programming search for LVCSR (2002)

This paper gives an overview of recent improvements in dynamic programming search methods for large-vocabulary continuous speech recognition (LVCSR): searching using lexical trees, time-conditioned searching and word graph construction.
Interferometric technique for the reduction of scattered light (1977)

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Nonoperative versus operative treatment for displaced midshaft clavicle fractures in adolescents: a comparative study (2018)

We aimed to compare the outcomes and complications of nonoperative and operative treatment for displaced midshaft clavicle fractures in adolescents. Radiological and functional evaluations and complications for 23 patients with nonoperative treatment were compared with those for 18 patients with operative treatment. No nonunion developed in either group. No significant intergroup differences were observed for occurrence of delayed union or time to union (P=0.851 and 0.887, respectively). Both groups showed excellent functional outcomes on the basis of Disabilities of the Arm, Shoulder and Hand scores and Constant Shoulder Scores. Shoulder abduction strength and range of motion were also well restored in both treatment groups. However, recovery of shoulder range of motion was significantly faster in the operative group (mean: 5.3 weeks; range: 4.0-7.0 weeks) than in the nonoperative group (mean: 9.9 weeks; range: 8.0-19.0 weeks) (P<0.001). There were no patients in either treatment group who needed revisional surgery to address complications with functional deficits. Both nonoperative and operative treatments yielded excellent outcomes, without severe complications. On the basis of our results, nonoperative treatment is recommended as a primary treatment option for displaced midshaft clavicle fractures in adolescents. However, operative treatment can be considered in selected patients who require early functional recovery or have a high activity level.
Performance Comparison of IEEE 802.1 TSN Time Aware Shaper (TAS) and Asynchronous Traffic Shaper (ATS) (2019)

The IEEE 802.1 time sensitive networking working group has recently standardized the time aware shaper (TAS). The TAS provides deterministic latency guarantees but requires tight time synchronization in all network switches. This paper thoroughly evaluates the mean and maximum packet delays and packet losses of the TAS for a typical industrial control ring network for random (sporadic) and for periodic traffic. We propose and evaluate adaptive bandwidth sharing and adaptive slotted window mechanisms to make TAS adaptive to traffic fluctuations. This paper further evaluates the asynchronous traffic shaper (ATS), which has been proposed to provide low latency network service without the need for time synchronization in network nodes. Our evaluations indicate that TAS with proper configurations, e.g., accurate and precise gating schedules, generally achieves the specified latency bounds for both sporadic and periodic traffic. In contrast, ATS performs relatively well for sporadic traffic; but struggles for moderate to high loads of periodic traffic.
Differential liquid and protein clearance from the alveoli of anesthetized sheep (1982)

We determined the clearance rates of 50 ml of isosmotic fluids from the lungs of anesthetized, ventilated sheep with lung lymph fistulas. The removal of the liquid volume followed a monoexponential process over 4 h for both Ringer lactate [half time (t 1/2) = 3 h] and autologous serum (t 1/2 = 6 h). Lymph flow did not increase with Ringer lactate, indicating that the alveolar fluid was cleared via the circulation. With serum, however, lymph flow increased 40%. In both groups the lymph-to-plasma protein concentration ratio fell slightly. Using protein tracers in the alveolar instillate, we found that less than 2% of the protein entered the lymph and plasma. Almost all of the protein remained in the air spaces and was concentrated in proportion to the amount of liquid volume that was cleared. Clearance of liquid volume from alveoli to interstitium could be due to subatmospheric interstitial fluid pressure or to active metabolic processes that cause small molecules to leave the alveolar fluid, or both. The results of the serum experiments tend to favor a metabolic process, but passive mechanisms are possible. The difference in lymph flow response between the two fluids must be due to the protein in the alveolar fluid. We believe Ringer lactate dilutes the alveolar wall interstitial protein concentration thereby decreasing local filtration, whereas serum concentrates alveolar wall interstitial fluids proteins thereby increasing local filtration.
A convolutional interleaver for LTE based mobile satellite systems (2009)

In this paper, we present a convolutional interleaver designed for mobile satellite communication systems based on 3GPP Long Term Evolution (LTE) standard. Because of long round trip delay (RTD) of satellite systems, adaptive modulation and coding scheme cannot compensate short term mobile fading effect. For this reason, an interleaver should be employed in conjuction with adaptive transmission schemes. Considering a long RTD of 0.5 second for a geostationary satellite system, we present interleaver design to compensate short fading lasts a few milliseconds.
Soft‐input bit‐flipping decoding of generalised concatenated codes for application in non‐volatile flash memories (2018)

Error correction coding based on soft‐input decoding can significantly improve the reliability of non‐volatile flash memories. This work proposes a soft‐input decoder for generalised concatenated (GC) codes. GC codes are well suited for error correction in flash memories for high reliability data storage. The authors propose GC codes constructed from inner extended binary Bose–Chaudhuri–Hocquenghem (BCH) codes and outer Reed–Solomon (RS) codes. The extended BCH codes enable an efficient hard‐input decoding. Furthermore, a low‐complexity soft‐input decoding method is proposed. This bit‐flipping decoder uses a fixed number of test patterns and an algebraic decoder for soft‐decoding. An acceptance criterion for the final candidate codeword is proposed. Combined with error and erasure decoding of the outer RS codes, this acceptance criterion can improve the decoding performance and reduce the decoding complexity. The presented simulation results show that the proposed bit‐flipping decoder in combination with outer error and erasure decoding can outperform maximum‐likelihood decoding of the inner codes.
A Comprehensive Model for Predicting Semiconductor Detector Performance (1976)

A Monte-Carlo computational model has been developed to simulate the photon and electron spectral response in semiconductor detectors. Source photons from 10 eV to 1 GeV are three-dimensionally absorbed in detectors of almost arbitrary shape. One-dimensional charge collection in an arbitrary electric field profile includes trapping and electronics system effects. HgI2, CdTe, and Ge spectra, as well as full energy peak and absorption efficiency calculations, are made into the MeV range.
Acoustic approach to thermal management: miniature thermoacoustic engines (2006)

An acoustic approach to thermal management in electronics can be efficient and it can be directly interfaced with electronic devices. It is based on two types of thermoacoustic heat engines, which are being developed for microcircuit applications. One type of device, the prime mover, converts heat to sound; energy is radiated away acoustically. This is achieved with essentially no moving parts. The other type of device, a heat pump or refrigerator, moves heat from one reservoir to another reservoir using sound waves. Both devices are resonant and hence their size scales inversely with operating frequencies. Devices presented here operate in the frequency range of 4 kHz to 21 kHz, depending on their size. The components are simple and they can be fabricated using microcircuit techniques. They consist of an acoustic resonator, heat exchangers, a stack of high surface area material for heat storage, and a working gas such as air or helium or gas mixture (He-Ar). The cooler has a loudspeaker to generate the sound for pumping heat, while the prime mover has a coupler to the source of heat. Working devices range in size from 2 cm to a few millimeters. Their efficiency, which depends on geometrical factors, is an appreciable fraction of Carnot. An important feature is a high power density. Working models and modeling show that power densities of several watts per cubic centimeter can be achieved by optimizing the parameters and working conditions. Performance characteristics of miniature prime movers and refrigerators will be presented
<i>C</i> <sub>2</sub>-Symmetric Bioxazolines and Bithiazolines as New Chiral Ligands for Metal Ion Catalyzed Asymmetric Syntheses: Asymmetric Hydrosilylation (1991)

New chiral C2 -symmetric bioxazolines (4,4′ -disubstituted 4,5,4′ ,5′ -tetrahydro-2,2′ -bioxazoles) and bithiazolines (4,4′ -disubstituted 4,5,4′ ,5′ -tetrahydro-2,2′ -bithiazoles) obtained in a few simple steps from amino acids were found to induce up to 84% enantiomeric excess in the rhodium(I)-catalyzed asymmetric hydrosilylation of acetophenone.
An On-Chip-Trainable Gaussian-Kernel Analog Support Vector Machine (2010)

An analog circuit architecture of Gaussian-kernel support vector machines having on-chip training capability has been developed. It has a scalable array processor configuration and the circuit size increases only in proportion to the number of learning samples. Thanks to the hardware-friendly algorithm employed in the present work, the learning function is realized by attaching a small additional circuitry to the SVM classifying hardware. The SVM classifying hardware is composed as an array of Gaussian circuits. Although the system is inherently analog, the input and output signals including training results are all available in digital format. Therefore, the learned parameters are easily stored and reused after training sessions. A proof-of concept chip containing 2-class, 2-D, 12-template classifier was designed and fabricated in a 0.18-μm CMOS technology. The experimental results obtained from the fabricated chips are presented and compared with theoretical calculation results. It can classify 8.7 x 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> vectors per second and the average power dissipation was 220 μW. The learning capability was tested using eight fabricated chips and the variability among these chips were evaluated. Successful operation of the chips was confirmed by measurement results, which demonstrates that on-chip-learning can compensate for analog imperfections.
Simulation of the microscopic process during initiation of stent thrombosis (2014)

During the initiation of stent thrombosis, platelets do not necessarily enter recirculation regions or deposit on endothelium near struts, as suggested by previous computational fluid dynamics simulations. Rather, platelets are more likely to deposit on activated endothelium outside recirculation regions and deposit directly on struts. Our study elucidated the effects of different mechanical factors on the roles of platelets and endothelium in stent thrombosis.
Study of a Convenient Method for the Preparation of Hydrosoluble Fluorescent Triazatruxene Derivatives (2009)

Abstract Triazatruxene derivatives find many applications as lipophilic compounds, but few examples of hydrosoluble derivatives have been reported so far. In this paper, we compare different synthetic routes for the preparation of hydrophilic triazatruxene derivatives and define the most versatile pathway. The synthesized compounds are fluorescent not only in organic solvents, as reported for other lipophilic derivatives, but also in water, making them particularly suitable for biological applications.