gebhart/patrepeval huggingface dataset:
Inhaled Corticosteroid Reduction and Elimination in Patients With Persistent Asthma Receiving Salmeterol<SUBTITLE>A Randomized Controlled Trial</SUBTITLE> (2001)

Our results indicate that in patients with persistent asthma suboptimally controlled by triamcinolone therapy alone but whose asthma symptoms improve after addition of salmeterol, a substantial reduction (50%) in triamcinolone dose can occur without a significant loss of asthma control. However, total elimination of triamcinolone therapy results in a significant deterioration in asthma control and, therefore, cannot be recommended.
Nonspecific binding removal from protein microarrays using thickness shear mode resonators (2006)

Nonspecific binding is a universal problem that reduces bioassay sensitivity and specificity. We demonstrate that ultrasonic waves, generated by 5-MHz quartz crystal resonators, accelerate nonspecifically bound protein desorption from sensing and nonsensing areas of micropatterned protein arrays, controllably and nondestructively cleaning the micropatterns. Nonsensing area fluorescent intensity values dropped by more than 85% and sensing area fluorescent intensity dropped 77% due to nonspecific binding removal at an input power of 14 W. After patterning, antibody films were many layers thick with nonspecifically bound protein, and aggregates obscured patterns. Quartz crystal resonators removed excess antibody layers and aggregates leaving highly uniform films, as evidenced by smaller spatial variations in fluorescent intensity and atomic force microscope surface roughness values. Fluorescent intensity values obtained after 14-W QCR operation were more repeatable and uniform.
Reduction in Cache Memory Power Consumption based on Replacement Quantity (2011)

Today power consumption is considered to be one of the important issues. Therefore, its reduction plays a considerable role in developing systems. Previous studies have shown that approximately 50% of total power consumption is used in cache memories. There is a direct relationship betw een power consumption and replacement quantity made in cache. The less the nu mber of replacements is, the less the power consumption is. In this paper, a mec hanism was proposed a mechanism to reduce power consumption using full as sociative organization and layered replacement algorithm. In this scheme, all cache blocks were divided into three layers. Final layer used FIFO replacement alg orithm and middle layer used random replacement algorithm. Also first layer used LRU replacement algorithm. Simulation results were shown using tools written b y VB language that in the proposed plan the number of replacement was less th an 8-way associative using LRU replacement algorithm.
Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities. (1994)

The three-dimensional structures of (1-->3)-beta-glucanase (EC 3.2.1.39) isoenzyme GII and (1-->3,1-->4)-beta-glucanase (EC 3.2.1.73) isoenzyme EII from barley have been determined by x-ray crystallography at 2.2- to 2.3-A resolution. The two classes of polysaccharide endohydrolase differ in their substrate specificity and function. Thus, the (1-->3)-beta-glucanases, which are classified amongst the plant "pathogenesis-related proteins," can hydrolyze (1-->3)- and (1-->3,1-->6)-beta-glucans of fungal cell walls and may therefore contribute to plant defense strategies, while the (1-->3,1-->4)-beta-glucanases function in plant cell wall hydrolysis during mobilization of the endosperm in germinating grain or during the growth of vegetative tissues. Both enzymes are alpha/beta-barrel structures. The catalytic amino acid residues are located within deep grooves which extend across the enzymes and which probably bind the substrates. Because the polypeptide backbones of the two enzymes are structurally very similar, the differences in their substrate specificities, and hence their widely divergent functions, have been acquired primarily by amino acid substitutions within the groove.
Increased production of <i>Bacillus</i> keratinase by chromosomal integration of multiple copies of the <i>kerA</i> gene (2004)

To increase the production of keratinase, stable strains of Bacillus licheniformis carrying multiple keratinase gene copies in the chromosome were developed. Integrative vectors carrying kerA with or without P43-promoter were constructed and subcloned into B. licheniformis T399D and Bacillus subtilis DB104. In T399D, multiple copies of kerA integration into the chromosome were identified and determined by Southern blot. The optimal integration of kerA was found in the range of 3-5 copies. Higher integration of gene copies (>5) caused reduced processing and secretion of the extracellular keratinase. In DB104, kerA was cloned in the plasmid, not integrated into the chromosome. The strong constitutive promoter P43 not only increased the keratinase production in plasmid-based expression in DB104 but also improved the enzyme yield of the integrants of T399D. New strains were able to enhance cell growth and enzyme yield at higher concentrations of medium substrate. When they were grown in either soy or feather medium, the keratinase activity was stable and improved by about 4-6 times.
Heteropolytungstate complexes of the lanthanide elements. Part I. Preparation and reactions (1971)

Salts of the anions LnIIIW10O357–(Ln = La, Ce, Pr, Nd, Sm, Ho, Er, Yb, and Y) and CeIVW10O356– have been prepared and analysed. The formulae of the previously reported 8-tungstocerates are revised. All the anions are unstable outside the pH range 5·5–8·5, and stable solutions of the free acids cannot be obtained. Lanthanide cations react rapidly with unsaturated heteropolyanions to give complexes LnL and LnL2(L = SiW11O398–, etc.). Salts of several of the LnL2 complexes have been isolated. The mode of co-ordination of L is discussed.
Ultrasonic Thermometry for Nuclear Reactors (1969)

Ultrasonic thermometry, based on the temperature dependence of sound velocity in solids, has been demonstrated under ideal laboratory conditions beyond 6000R. Integrated fluxes (nvt) of 2.6 × 1019 fast and 8.7 × 1019 thermal do not perturb the velocity/temperature relationship. Ta protective sheaths prevented carbon contamination for 1 hr at 5100R, in a program simulating temperature measurements in the graphite/hydrogen atmosphere of a nuclear rocket engine. Tests have also been performed in liquid sodium at 1200R, and separately, inside a 1.6 mm dia Ta tube heated to 5500R, simulating temperatures inside UO2-fueled pins of fast breeder reactors.
BreathPrint (2017)

We propose BreathPrint, a new behavioural biometric signature based on audio features derived from an individual's commonplace breathing gestures. Specifically, BreathPrint uses the audio signatures associated with the three individual gestures: sniff, normal, and deep breathing, which are sufficiently different across individuals. Using these three breathing gestures, we develop the processing pipeline that identifies users via the microphone sensor on smartphones and wearable devices. In BreathPrint, a user performs breathing gestures while holding the device very close to their nose. Using off-the-shelf hardware, we experimentally evaluate the BreathPrint prototype with 10 users, observed over seven days. We show that users can be authenticated reliably with an accuracy of over 94% for all the three breathing gestures in intra-sessions and deep breathing gesture provides the best overall balance between true positives (successful authentication) and false positives (resiliency to directed impersonation and replay attacks). Moreover, we show that this breathing sound based biometric is also robust to some typical changes in both physiological and environmental context, and that it can be applied on multiple smartphone platforms. Early results suggest that breathing based biometrics show promise as either to be used as a secondary authentication modality in a multimodal biometric authentication system or as a user disambiguation technique for some daily lifestyle scenarios.
Design principles of sequentially fed, wide bandwidth, circularly polarised microstrip antennas (1989)

The technique of sequentially rotating the feed position of a microstrip patch antenna to improve the circular polarisation bandwidth of an array of such elements is briefly reviewed in the wider context of other known antenna parameterstaggering concepts. A first order analysis then shows how the sequential technique significantly improves the axial ratio bandwidth in relation to the number of patches in the array and the feeder connections. Unwanted effects such as feeder phase errors, multiple reflections in feeders, the presence of higher order modes and mutual coupling are then considered. Computations embracing these effects and measurements illustrate the various properties and topological options available. Finally, the application of the technique is briefly illustrated for a single patch and an array of patches. In conclusion the design principles are summarised and feeder effects are identified as the main limitation when implementing the sequential technique.
"Development of lithium disilicate microstructure graded glass-ceramic" (2012)

The goal of this research was to create a microstructure graded glass-ceramic and investigate the resulting properties as a function of crystallization processing. The desired glass-ceramic was a lithium disilicate material that has a crystallization gradient across the sample, leading to functionally graded properties as a result of the microstructure gradient. Samples were prepared by melting and pouring glass at 1400°C, annealing at 400°C for 48 hours, and nucleating at 480°C for 2 hours. To ensure that crystallization would not occur homogeneously throughout the sample, a temperature gradient was imposed during crystallization. Samples were crystallized on a self-constructed resistance wire furnace that was open to air. Several crystallization processing parameters were tested, including high temperature for a short time and low temperature for a long time. Samples were ground and polished to 0.25 microns before characterization methods were performed. Scanning electron microscopy (SEM) showed the microstructure transition across the sample cross section, with crystals present on the crystalline side and only nuclei present on the glassy side. Raman spectroscopy showed a transformation of the characteristic spectra across the sample cross section, with defined, high-intensity peaks on the crystalline side and broad, low-intensity peaks on the glassy side. Microhardness showed a slight transition in hardness values across the sample cross section, however the variability was too great to draw any conclusions. The characterization methods showed that the desired material was created and the resulting properties were a function of the crystallization processing parameters.
Nitric Phosphates from Phosphate Rock, Nitric Acid, Ammonia, and Carbon Dioxide (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNitric Phosphates from Phosphate Rock, Nitric Acid, Ammonia, and Carbon DioxideF. T. Nielsson, L. D. Yates, L. F. Roy, and F. G. HeilCite this: J. Agric. Food Chem. 1953, 1, 17, 1050–1054Publication Date (Print):November 1, 1953Publication History Published online1 May 2002Published inissue 1 November 1953https://pubs.acs.org/doi/10.1021/jf60017a003https://doi.org/10.1021/jf60017a003research-articleACS PublicationsRequest reuse permissionsArticle Views70Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Helping the poor manage risk better : the role of social funds (1999)

Recent trends in trade, technology, and politics have created new opportunities for global welfare improvement, but have also increased risks. This challenge requires rethinking social protection, and its instruments, particularly social funds. This paper reviews social funds, and suggests future directions by using a"social risk management"framework, to examine how social funds can help the poor manage risk better. Risk management covers risk reduction, risk mitigation, and risk coping. Analyzing social funds within the social risk management framework, suggests that: they should be assessed as one of many components in countries'social risk management strategies; they should move from coping and mitigation, to risk reduction; they should focus more on the medium term impact of projects; their targeting should focus on vulnerability, and vulnerable groups; their"investment menus"should be expanded to include more risk reduction projects; and, more emphasis should be given to participation, and capacity building.
A 32-mW 40-Gb/s CMOS NRZ transmitter (2018)

A wireline transmitter with 2-tap feedforward equalization achieves more than a two-fold improvement in the power efficiency through the use of a new integrating multiplexer, as well as quadrature clock phases with 25% duty cycle. Serializing data by a factor of 128 and including an on-chip phase-locked loop, the transmitter is realized in 45-nm CMOS technology and delivers a differential output swing of 460 mV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">pp</sub> .
Surface Relaxations in Polymers (1997)

Near-edge X-ray absorption fine structure, NEXAFS, spectroscopy was used to investigate the relaxations of polystyrene, a typical amorphous polymer, near a free surface after the imposition of a small deformation. Using synchrotron radiation, the NEXAFS dichroic ratio was determined for both the Auger and total electron yield processes as a function of temperature to determine the orientation of the polymer in the first 1 and 10 nm from the free surface, respectively. Complete relaxation of the polymer was not seen for temperatures less than the bulk glass transition temperature. No evidence of enhanced mobility at the free surface was found. A planar relaxation of the polymer was found in the first nanometer from the free surface, whereas in the first 10 nm, the dominant relaxation was normal to the surface.
Schools for community activists: A report of the first decade's experience (1993)

This article describes “schools for community activists” held in Israel since 1980 and briefly summarizes a study of 1,070 graduates of these courses. The aims, structure, content, and organization of the courses are described and placed within the context of the limited professional literature on the subject.
For sale: Mood Tuscany for your living room (2004)

Most consumer products are designed with the average user in mind.Wallpaper, stereo, lighting equipment, none of them contain any knowledge about the specific, changing wishes of their owner. Once bought, they never change. At the Studio Home Lab of the Delft faculty of Industrial Design, researchers are investigating how music, lighting and art can instantly change the atmosphere in your living room. They have developed models of moods such as romantic, quiet, snug, cosy,chaotic, and business-like. The result is an integrated atmosphere control unique in the world. The system can be operated by anything from a mobile display on which users click to make their selections to voice-operated control. One of the innovative controls devised by the Delft researchers is a small wooden work of art that the user can shape to express his personal mood. In addition to choosing their type of control,they may one day be able to exchange living room moods in digital form with Internet users all over the world.
Relation between breakdown mode and breakdown location in short channel NMOSFETs and its impact on reliability specifications (2002)

A method to determine the breakdown position in short channel nMOSFETs is introduced. We find that soft breakdown occurs exclusively in the transistor channel while the hardest circuit killing breakdowns occur above the source and drain extension regions. Since these breakdowns make up only a small fraction of all breakdowns, a relaxation of the reliability specification is possible.
Floppy Eyelid Syndrome as a Subset of Lax Eyelid Conditions: Relationships and Clinical Relevance (an ASOPRS Thesis) (2010)

Eyelid laxity can result from a number of involutional, local, and systemic diseases but is frequently of unknown etiology. When it is consistently associated with papillary conjunctivitis and dry eyes it can be referred to as lax eyelid syndrome (LES). A number of specific subsets of LES can be identified. One such subset, occurring primarily though not exclusively in males and associated with obesity, has been defined as the floppy eyelid syndrome (FES). OSA has been associated with FES where it occurs with greater frequency than in the general population, but no greater than seen in obese males without FES, and therefore appears to represent an epiphonomenom only. However, given the demographics of FES, this condition offers some predictive value for OSA and should alert the physician to evaluate the sleep habits of all such patients. Keratoconus also shows some association with FES and with LES. However, data suggest that the causative factors are sleep preference for the involved side and nocturnal eyelid eversion, rather than any underlying physiologic or anatomic relationship.
Efficiency improvement in polycrystalline silicon solar cell with grooved surface (2002)

A surface grooving technique for realizing uniform low reflectance over polycrystalline silicon substrates has been developed. Lower surface reflectance is obtained by the adoption of a double-layer antireflection coating. The highest conversion efficiency has been achieved for a 10 cm-square polycrystalline silicon solar cell with a double-layer antireflection coating formed on the grooved surface.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
In vivo kinetics of kinase domain mutations in CML patients treated with dasatinib after failing imatinib (2007)

We sought kinase domain (KD) mutations at the start of treatment with dasatinib in 46 chronic myeloid leukemia (CML) patients resistant to or intolerant of imatinib. We identified BCR-ABL mutant subclones in 12 (26%) cases and used pyrosequencing to estimate subsequent changes in their relative size after starting dasatinib. Four patients lost their mutations, which remained undetectable, 3 patients retained the original mutation or lost it only transiently, 3 lost their original mutations but acquired a new mutation (F317L), and 2 developed another mutation (T315I) in addition to the original mutation within the same subclone. This study shows that expansion of a mutant Ph-positive clone that responds initially to a second generation tyrosine kinase inhibitor may be due either to late acquisition of a second mutation in the originally mutated clone, such as the T315I, or to acquisition of a completely new mutant clone, such as F317L.
Class- and Molecule-specific Differential Effects of Angiotensin II Type 1 Receptor Blockers (2013)

Angiotensin II (Ang II) type 1 (AT1) receptor is a member of the G protein-coupled receptor superfamily and contains 359 amino acids. AT1 receptor blockers (ARBs, e.g., eprosartan, losartan, candesartan, valsartan, telmisartan, olmesartan, irbesartan, and azilsartan) have been developed and are available for clinical use, and basic and clinical studies have shown that ARBs are useful for preventing the development of cardiovascular disease. While most ARBs have common molecular structures (biphenyl-tetrazol and imidazole groups), they also show slightly different structures. Some of the benefits conferred by ARBs may not be class-specific effects, and instead may be molecule-specific effects. Their common molecular structures are thought to be responsible for their class effects, whereas their slightly different structures may be important for promoting molecule-specific effects. This review focuses on current evidence regarding the class- and molecule-specific differential effects of ARBs from basic experiments to clinical settings.
A Rapid Total Synthesis of Spirotryprostatin B: Proof of Its Relative and Absolute Stereochemistry (2000)

A Mannich-insertion strategy was employed in the synthesis of cytostatic 1. The synthesis allowed the absolute and relative stereochemistry to be confirmed and yielded quantities of 1 suitable for upcoming biological testing. Boc=tert-butoxycarbonyl.
서울시 셰어하우스 1인당 임대료 결정요인에 관한 연구 (2018)

This study attempts to investigate the determinants of rent prices for share house in Seoul through empirical analyses with using Hedonic Price Model. This study data were collected from hompages of share house companies. The spatial scope of this study was limited in Seoul and the temporal scope was limited from September 2016 to March 2017. The collected data included monthly rent prices per one person, regional characteristics, building characteristics, and share house management characteristics. According to the result of this study, in the regional characteristics, there is a difference by regional locations in the rent prices of share house. The regional variables, which are Gangnam-Gu, Mapo-Gu, Yeongdeungpo-Gu, and Yongsan-Gu, increase the rent prices. As the distance of subway station and market become shorter, the rent prices become higher. Also, as the transfer of subway station becomes possible, the rent prices are raised. These results are reflected in the desire of convenience for purchasing foods and using public transportation. In case of commercial buildings, it is associated with higher rent prices than other types of buildings, whereas the multi-household house variable is associated with lower rent prices. Also, as the number of bathroom in share house increases, the rent prices are decreased. As the area of room in share house become wider, the rent prices are increased. From the result of the variable which is room type of share house, we could know that the rent prices are decreased as many people live with sharing a room as possible. The implication of this study is that it analyzes share house which is one of alternatives to solve problems such as poor housing of young single households, and suggests the trend and efficient management of share house. Here we expect that our research about share house, which has not studies actively yet, would contribute to the improvement for support and policies of share house.