gebhart/patrepeval huggingface dataset:
Image‐Based Surface Compression (2008)

Abstract We present a generic framework for compression of densely sampled three‐dimensional (3D) surfaces in order to satisfy the increasing demand for storing large amounts of 3D content. We decompose a given surface into patches that are parameterized as elevation maps over planar domains and resampled on regular grids. The resulting shaped images are encoded using a state‐of‐the‐art wavelet image coder. We show that our method is not only applicable to mesh‐ and point‐based geometry, but also outperforms current surface encoders for both primitives.
Reovirus Binding Determinants in Junctional Adhesion Molecule-A (2007)

Junctional adhesion molecule-A (JAM-A) serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). The membrane-distal immunoglobulin-like D1 domain of JAM-A is required for homodimerization and binding to reovirus attachment protein sigma1. We employed a structure-guided mutational analysis of the JAM-A dimer interface to identify determinants of reovirus binding. We purified mutant JAM-A ectodomains for solution-phase and surface plasmon resonance binding studies and expressed mutant forms of full-length JAM-A in Chinese hamster ovary cells to assess reovirus binding and infectivity. Mutation of residues in the JAM-A dimer interface that participate in salt-bridge or hydrogen-bond interactions with apposing JAM-A monomers abolishes the capacity of JAM-A to form dimers. JAM-A mutants incapable of dimer formation form complexes with the sigma1 head that are indistinguishable from wild-type JAM-A-sigma1 head complexes, indicating that sigma1 binds to JAM-A monomers. Residues Glu(61) and Lys(63) of beta-strand C and Leu(72) of beta-strand C' in the dimer interface are required for efficient JAM-A engagement of strain type 3 Dearing sigma1. Mutation of neighboring residues alters the kinetics of the sigma1-JAM-A binding interaction. Prototype reovirus strains type 1 Lang and type 2 Jones share similar, although not identical, binding requirements with type 3 Dearing. These results indicate that reovirus engages JAM-A monomers via residues found mainly on beta-strands C and C' of the dimer interface and raise the possibility that the distinct disease phenotypes produced in mice following infection with different strains of reovirus are in part attributable to differences in contacts with JAM-A.
Performance evaluation in network computers (1973)

In this paper we present some results obtained from using simulation as a tool for evaluating alternative methods of improving system performance in network computers. We begin by describing a GPSS model which was developed to evaluate the current computer center operations at the University of Illinois. While using actual data from the center to verify that the model accurately predicts each job's total time in the system, we evaluate the resource utilization within the center. Then we use the simulator to show that a proposed dynamic priority assignment algorithm yields better throughput than the existing algorithm while maintaining a higher level of CPU and memory utilization.Next, turning our attention to a hypothetical network of three centers, we use a generalization of our model to demonstrate the effects of load leveling between centers on the total system throughput. Here we also explore the merits of “pay-for-priority” schemes in both a single center and in a network of three centers.Finally, we discuss the process of tuning the simulator model to the real world system including the problems of benchmark data generation and system parameter determination.
Upconversion-induced fluorescence in multicomponent systems: Steady-state excitation power threshold (2008)

We have analyzed the dynamics of the upconversion-induced delayed fluorescence for a model multicomponent organic system, in which high concentrations of triplet states can be sustained in steady-state conditions. At different excitation powers, two regimes have been identified depending on the main deactivation channel for the triplets, namely, the spontaneous decay and the bimolecular annihilation. The excitation power density at which triplet bimolecular annihilation becomes dominant is the threshold $({I}_{\text{th}})$ to have efficient upconversion generation. The simple equation obtained for ${I}_{\text{th}}$ allows us to predict the theoretical efficiency of a generic system on the basis of few parameters of the constituent molecules.
Obstructive sleep apnoea (OSA) - a silent killer in anaesthesia? : review (2007)

Sleep-disordered breathing (SDB) encompasses a wide range of disorders that afflict both adults and children. These disorders are often unrecognised preoperatively and the pathophysiological consequences may impact severely on the patient in the peri-operative period.
Dose of Compound A, Not Sevoflurane, Determines Changes in the Biochemical Markers of Renal Injury in Healthy Volunteers (1999)

Administration of sevoflurane in a circle absorption system generates Compound A, a nephrotoxin in rats.Reports examining the potential of Compound A to produce renal injury in humans have provided conflicting results. We tested the possibility that there is a threshold to Compound A-induced renal injury in humans and that, above this threshold, renal injury increases with increasing doses of Compound A. Eleven volunteers received 3% sevoflurane for 8 h at 2 L/min, and three volunteers received 3% sevoflurane for 8 h at 4-6 L/min. We measured inspired and expired concentrations of Compound A and urinary excretion of albumin, alpha-glutathione-S-transferase (GST), and glucose. The median urinary excretion of albumin, glucose, and alpha-GST for the first 3 days after anesthesia increased significantly from preanesthetic values in the 2-L/min group. Compound A doses <240 ppm-h resulted in normal urinary excretion of albumin, glucose, and alpha-GST. Five of seven subjects who received doses >240 ppm-h had abnormal excretion of albumin, and six of seven had abnormal alpha-GST urinary excretion (P < 0.05). Urinary excretion of albumin, alpha-GST, and glucose was normal by 14 days after exposure. We conclude that sevoflurane administration for 8 h at 2 L/min results in albuminuria and enzymuria when the dose of Compound A exceeds 240 ppm-h. That is, a Compound A concentration of 30 ppm breathed for >or=to8 h may produce transient renal injury. Implications: We examined the dose-response relationship of sevoflurane/Compound A and urinary excretion of albumin, glucose, and alpha-GST. Sevoflurane exposure for 8 h at a 2-L/min inflow rate produces transient albuminuria and enzymuria in healthy volunteers when the dose of Compound A exceeds 240 ppm-h (30 ppm for 8 h). (Anesth Analg 1999;88:437-45)
Optimization of Detection Time for Channel Efficiency in Cognitive Radio Systems (2007)

In cognitive radio (CR) systems, secondary users (SUs) have to detect the channel periodically during their data transmission to decide whether the channel is idle in order to avoid unacceptable interferences to primary users (PUs). The duration of the detection process in a cycle affects the channel efficiency of the SU. Also, the detection time needs to be adaptively adjusted due to path loss variations caused by movements of PUs and SUs. In this paper, we explore the issue on the detection time selection that aims at improving the channel efficiency. We formulate this issue as an optimization problem, but it is extremely difficult to get the explicit solution. A numerical optimization algorithm is proposed to obtain the numerical solution to the problem. Numerical results show that the highest channel efficiency can be achieved by the optimization of the detection time.
An asynchronous dataflow FPGA architecture (2004)

We discuss the design of a high-performance field programmable gate array (FPGA) architecture that efficiently prototypes asynchronous (clockless) logic. In this FPGA architecture, low-level application logic is described using asynchronous dataflow functions that obey a token-based compute model. We implement these dataflow functions using finely pipelined asynchronous circuits that achieve high computation rates. This asynchronous dataflow FPGA architecture maintains most of the performance benefits of a custom asynchronous design, while also providing postfabrication logic reconfigurability. We report results for two asynchronous dataflow FPGA designs that operate at up to 400 MHz in a typical TSMC 0.25 /spl mu/m CMOS process.
Hot Spot Dynamics in Quasi Vertical DMOS under ESD Stress (2003)

Quasi vertical DMOS transistors in a 90V Smart Power Technology are studied under ElectroStatic Discharge (ESD) stress. Movement of current filaments and multiple hot spots are observed ouder snap-back conditions. The hot spot dynamics are explained in terms of the movement of a base push-out region across the cell field as a consequence of the temperature dependence of avalanche generation. The described mechanisms help homogenizing the time averaged current density distribution and enhance the device robustness against ESD events.
Genome-Wide Identification of <i>S</i> <i>accharomyces cerevisiae</i> Genes Required for Maximal Tolerance to Ethanol (2009)

The understanding of the molecular basis of yeast resistance to ethanol may guide the design of rational strategies to increase process performance in industrial alcoholic fermentations. In this study, the yeast disruptome was screened for mutants with differential susceptibility to stress induced by high ethanol concentrations in minimal growth medium. Over 250 determinants of resistance to ethanol were identified. The most significant gene ontology terms enriched in this data set are those associated with intracellular organization, biogenesis, and transport, in particular, regarding the vacuole, the peroxisome, the endosome, and the cytoskeleton, and those associated with the transcriptional machinery. Clustering the proteins encoded by the identified determinants of ethanol resistance by their known physical and genetic interactions highlighted the importance of the vacuolar protein sorting machinery, the vacuolar H(+)-ATPase complex, and the peroxisome protein import machinery. Evidence showing that vacuolar acidification and increased resistance to the cell wall lytic enzyme beta-glucanase occur in response to ethanol-induced stress was obtained. Based on the genome-wide results, the particular role of the FPS1 gene, encoding a plasma membrane aquaglyceroporin which mediates controlled glycerol efflux, in ethanol stress resistance was further investigated. FPS1 expression contributes to decreased [(3)H]ethanol accumulation in yeast cells, suggesting that Fps1p may also play a role in maintaining the intracellular ethanol level during active fermentation. The increased expression of FPS1 confirmed the important role of this gene in alcoholic fermentation, leading to increased final ethanol concentration under conditions that lead to high ethanol production.
Multispectral polarization viewing angle analysis of circular polarized stereoscopic 3D displays (2010)

In this paper we propose a method to characterize polarization based stereoscopic 3D displays using multispectral Fourier optics viewing angle measurements. Full polarization analysis of the light emitted by the display in the full viewing cone is made at 31 wavelengths in the visible range. Vertical modulation of the polarization state is observed and explained by the position of the phase shift filter into the display structure. In addition, strong spectral dependence of the ellipticity and polarization degree is observed. These features come from the strong spectral dependence of the phase shift film and introduce some imperfections (color shifts and reduced contrast). Using the measured transmission properties of the two glasses filters, the resulting luminance across each filter is computed for left and right eye views. Monocular contrast for each eye and binocular contrasts are performed in the observer space, and Qualified Monocular and Binocular Viewing Spaces (QMVS and QBVS) can be deduced in the same way as auto-stereoscopic 3D displays allowing direct comparison of the performances.
Virtual reality debuts in the teaching laboratory in nursing. (1996)

This article describes the development and implementation of a Prototype Procedural Simulator for Nursing Education for Intravenous. With a private gift from alumni, the faculty of the Nursing Department at the State University of New York worked with the firm High Techsplantions (Rockville, Maryland) to develop a virtual reality simulation to be used to teach student nurses how to insert intravenous needles. Although originally developed for use in nursing education, the Prototype Procedural Simulator for Nursing Education for Intravenous can be used in any teaching program in which the students have responsibility for inserting needles into veins (eg, medical students, laboratory technicians, emergency medical personnel, and physicians' assistants).
Use of bicistronic retroviral vectors encoding the LacZ gene together with a gene of interest: a method to select producer cells and follow transduced target cells. (1996)

The coordinate expression of a marker gene and a therapeutic gene in one retroviral vector has considerable advantages. High-titer producer lines can potentially be selected on the basis of marker gene expression, and the expression of transduced genes in target cells can readily be followed. Moreover, target cells with stable high expression can be selected before use in therapeutic protocols or research questions. We used internal ribosomal entry site (IRES) sequences to express two genes in the same retroviral vector. We used the LacZ gene as the marker gene and the cytokine interleukin (IL)-7 or dominant negative (dn) forms of the T-cell tyrosine kinases ZAP-70 and lck as genes of interest. Amphotropic packaging cells transfected with MFG-IL-7-IRES-LacZ, MFG-dnZAP-70-IRES-LacZ, or MFG-dnlck-IRES-LacZ were sorted on the basis of beta-galactosidase expression. These LacZ-positive producer cells also expressed the gene of interest, produced high-titer retrovirus, and were capable of efficiently transducing Jurkat T cells and T-cell clones. When MFG-IL-7-IRES-LacZ-transduced Jurkat T cells were sorted on the basis of LacZ expression, a positive correlation with the amount of IL-7 produced by these cells was found. This demonstrates that selection of the LacZ marker gene also selects for cells that express the gene of interest at high levels. Moreover, T cells transduced with the dn tyrosine kinases and selected on the basis of LacZ expression showed functional alterations after T-cell receptor stimulation, demonstrating that retrovirally transduced signaling molecules can alter the function of T cells
The Logging Technology for Determining Water-Intake Profile With the Radioisotopic Carriers (1997)

Abstract The logging technology of radioisotopic carriers has long been a main means to monitor and survey injection profiles in during water injection. This paper focuses on the basic principles of the logging technology, radioisotopic microballs, logging tools, auxiliary equipment, logging techniques, data interpretation, and application effects.
Simulation of metallic powder bed additive manufacturing processes with the finite element method: A critical review (2015)

This article provides a literature review of finite element simulation studies for metallic powder bed additive manufacturing processes. The various approaches in the numerical modeling of the processes and the selection of materials properties are presented in detail. Simulation results are categorized according to three major findings’ groups (i.e. temperature field, residual stresses and melt pool characteristics). Moreover, the means used for the experimental validation of the simulation findings are described. Looking deeper into the studies reviewed, a number of future directions are identified in the context of transforming simulation into a powerful tool for the industrial application of additive manufacturing. Smart modeling approaches should be developed, materials and their properties should be further characterized and standardized, commercial packages specialized in additive manufacturing simulation have to be developed and simulation needs to become part of the modern digital production chains. Finally, the reviewed studies are organized in a table and characterized according to the process and material studied, the modeling methodology and the experimental validation method used in each of them. The key findings of the reviewed studies are also summarized.
Virtual blood, real sweat, no tears: lessons learned from making a publication about electronic publications (2002)

The EIA Electronic Document Report (EDR) provides critical information and informed perspective for business people concerned with the role that electronic information will play in meeting the business objectives of enhanced performance and competitiveness. As publishers, we use the very technology and tools that the EDR describes for developing, managing, delivering, and using electronic documents. Creating an electronic publication about electronic documents required that we address readers' requirements as well as our own as publishers, develop and implement the right information model, assemble a top-notch staff, and, in essence, develop a radically new publication methodology. The EIA Electronic Document Report (EDR) is a diskette-based publication that provides critical information and informed perspective about the development, management, delivery, and use of electronic documents as a key requirement of modern business. But the EDR is more than just a new publication about electronic documents. It is a new kind of publication that employs the very technology and tools it describes, and making it work forced us to address the very issues that form its primary editorial content. In doing so, we had to go beyond the current vision of electronic document delivery and reject some of its prevailing tenets. Our experience with the first three issues forced us to rethink some of our own assumptions, too, but our insistence on moving beyond the current paradigm helped us avoid some serious technical and production problems, opened new business opportunities, and may give us a competitive edge in the future.
Carbon Dioxide and Energy Exchanges in the Coastal Zone of Hudson Bay (2011)

An eddy covariance system and micrometeorological station was deployed at two locations along the coastline of Hudson Bay during the summers of 2005 and 2006 to document and to understand mass and energy fluxes in high-latitude intertidal and near-shore environments. Despite the proximity of these two zones, it was found that they exhibited distinctly different characteristics. The near-shore zone was a sink for CO2 with an average uptake of -0.11 μmol·m-2·s-1 and the intertidal zone tended to be a source of CO2 with an average efflux of 0.04 μmol·m-2·s-1 with considerable variability due to the action of the tides. Sensible heat fluxes in the near-shore zone tended to be small and negative and both latent and sensible heat fluxes were significantly enhanced in the intertidal zone. Significantly, increasing wind velocities did not appear to play a role in the enhancement of these fluxes and onshore winds were observed to be unusually dry. As such, key differences were observed that stood in contrast to the results and the conclusions of other flux studies conducted in similar high-latitude coastal-marine environments. It is suggested that these differences could only be understood in the context of the proximity of these areas of living and dead kelp, their respective differences in water depth and the occasional occurrence of a sea-breeze effect that may have implications for the observed fluxes in these areas.
Time Slot Management in Attended Home Delivery (2010)

Many e-tailers providing attended home delivery, especially e-grocers, offer narrow delivery time slots to ensure satisfactory customer service. The choice of delivery time slots has to balance marketing and operational considerations, which results in a complex planning problem. We study the problem of selecting the set of time slots to offer in each of the zip codes in a service region. The selection needs to facilitate cost-effective delivery routes, but also needs to ensure an acceptable level of service to the customer. We present a fully automated approach that is capable of producing high-quality delivery time slot offerings in a short amount of time. Computational experiments reveal the value of this approach and the impact of the environment on the underlying trade-offs.
New Acetogenin Peroxides from the Indian Sponge <i>Acarnus bicladotylota</i> (2000)

Two new cyclic peroxides (1 and 2) and the known metabolite 3 have been found in the organic extract of the Indian sponge Acarnus bicladotylota. The structure of the new products has been assured by chemical and spectroscopic methods. The absolute stereochemistry of 1-3 has been determined by Mosher's method on the semisynthetic derivative 4.
Language Proficiency Modulates the Recruitment of Non-Classical Language Areas in Bilinguals (2011)

Bilingualism provides a unique opportunity for understanding the relative roles of proficiency and order of acquisition in determining how the brain represents language. In a previous study, we combined magnetoencephalography (MEG) and magnetic resonance imaging (MRI) to examine the spatiotemporal dynamics of word processing in a group of Spanish-English bilinguals who were more proficient in their native language. We found that from the earliest stages of lexical processing, words in the second language evoke greater activity in bilateral posterior visual regions, while activity to the native language is largely confined to classical left hemisphere fronto-temporal areas. In the present study, we sought to examine whether these effects relate to language proficiency or order of language acquisition by testing Spanish-English bilingual subjects who had become dominant in their second language. Additionally, we wanted to determine whether activity in bilateral visual regions was related to the presentation of written words in our previous study, so we presented subjects with both written and auditory words. We found greater activity for the less proficient native language in bilateral posterior visual regions for both the visual and auditory modalities, which started during the earliest word encoding stages and continued through lexico-semantic processing. In classical left fronto-temporal regions, the two languages evoked similar activity. Therefore, it is the lack of proficiency rather than secondary acquisition order that determines the recruitment of non-classical areas for word processing.
Monolithic integration of a semiconductor ring laser and a monitoring photodetector (1991)

A simple photonic integrated circuit consisting of a ring laser, a passive waveguide and a detector has been fabricated in GaAs/AlGaAs. A ring laser is employed as a source in this circuit because it is easily integrated with other components on the same substrate. The detector monitors the counterpropagating mode of the ring laser and shows no leakage current. The structure is easily fabricated by straightforward lithography and does not require overgrowth.