gebhart/patrepeval huggingface dataset:
Immunological properties of embryonic and adult stem cells (2010)

The possibility of treating degenerative diseases by stem cell-based approaches is a promising therapeutical option. Among major concerns for the clinical application of stem cells, some derive from the possibility that stem cells may be rejected by the immune system as a consequence of histoincompatibility and that stem cells themselves may interfere with the normal functions of host immune response. Therefore, the immunogenicity and the immunomodulatory properties of stem cells must be carefully addressed. Although these properties are common features of different stem cell types, some peculiarities can be recognized and characterized for their proper clinical use.
Scalable VLSI architecture for K-best lattice decoders (2008)

A scalable pipelined VLSI architecture for K-best lattice decoders featuring an efficient operation over infinite lattices is proposed. The proposed architecture operates at a significantly lower complexity than currently reported schemes. The key contribution is a means of expanding/visiting the intermediate nodes of the search tree on-demand, rather than exhaustively along with three types of distributed sorters operating in a pipelined structure. The combined expansion and sorting cores are able to find the K best candidates in just K clock cycles. Its support of the unbounded lattice decoding distinguishes our work from previous K-best strategies. Since the expansion and sorting cores cooperate on a data-driven basis, the architecture is well-suited for a pipelined parallel VLSI implementation. The proposed architecture has the lowest latency reported to-date, fixed critical path independent of the constellation order, on-demand expansion scheme, efficient distribute sorters, pipelined high-throughput implementation, and is scalable to higher number of antennas/constellation orders.
Comprehensive Endovascular Therapy for Femoropopliteal Arterial Atherosclerotic Occlusive Disease (2005)

Davies, Mark G. MD, PhD; Waldman, David L. MD, PhD; Pearson, Thomas A. MD, MPH, PhD Author Information
A novel candidate region for ALS on chromosome 14q11.2 (2004)

Sequence variations with biologic effect in ALS have been identified in the gene for vascular endothelial growth factor (VEGF). The gene for a related protein, angiogenin, lies on chromosome 14q11.2. Analysis of the angiogenin (ANG) gene in the authors' population has demonstrated a significant allelic association with the rs11701 single nucleotide polymorphism (SNP) and identified a novel mutation in two individuals with sporadic ALS that potentially inhibits angiogenin function. These observations propose a candidate region for ALS on chromosome 14q11.2 and suggest that other genes with similar function to VEGF may be important in the pathogenesis of ALS.
Safety of once-weekly alendronate 70 mg in the treatment of periodontal disease (2000)

Purpose: To evaluate the safety of once-weekly alendronate in the treatment of periodontal disease.
Digital Logic Testing and Testability (1991)

Abstract : Electronic hardware is subject to defects that are introduced at the time of manufacture and failures that occur in the field. Because of the complexity of digital logic circuits, they are difficult to test. This report provides an overview of digital logic testing. It provides access to the literature and unifies terminology and concepts that have evolved in this field. It discusses the types and causes of failures in digital logic. This report presents the topics of logic and fault simulation, fault grading, test generation algorithms, and fault isolation. The discussion of testability measurement is useful for understanding testability requirements and analysis techniques. Design -for-testability and built in test techniques are presented.
Selective mode excitation of graded index optical fibers (1978)

A method is described permitting excitation of a small number of modes in graded index fibers, the order of the launched mode being easily varied and determined. Using this launching technique, it is possible to determine the index profile and index difference of graded core fibers; results are compared with those obtained by other techniques. Other important fiber parameters, such as the differential attenuation and the differential propagation delay time as a function of the mode parameter, are also obtained, giving an insight into the fundamental propagation characteristics of the fiber.
[Quantitative analysis of tripchlorolide in pharmaceutical preparation by RP-HPLC]. (1992)

A reversed phase high performance liquid chromatographic method for the assay of tripchlorolide (T4) in pharmaceutical preparation was developed. The method used a Nucleosil 5 C18 column and a mobile phase of methanol-water (1:1). The column effluent was monitored at 218 nm. T4, triptolide (T0) and 1,4-dimethoxybenzene (IS) could be separated in less than 25 min. The retention times of T0, T4 and IS are 11, 17 and 23 min respectively. The method is very simple and rapid.
AN SQL interface for Common Lisp (1991)

Access to persistent database storage from Common Lisp applications is an increasingly frequent requirement. This paper discusses a software module that allows a Common Lisp program to access a relational database management system. Database queries are expressed as SQL statements. In Common Lisp, the SQL query is represented as a string, which allows sequence functions to be used to construct the query. Through a foreign function interface, the SQL query is passed from Lisp to a C component. The C component contains embedded database statements to utilize the dynamic SQL facility provided by the database management system. The database result table is returned to Lisp. Functions are provided to convert the returned data into a list of structures. Each structure corresponds to one row in the database result table. Structure accessor functions allow each individual attribute (field) in the structure representation of a row in the result table to be obtained.
Automatic Extraction Of Music Descriptors From Acoustic Signals. (2004)

[TODO] Add abstract here.
FABRICATION AND OPTIMISATION OF PLANAR SCHOTTKY DIODES (1997)

Aiming at a more reliable and cheaper fabrication the replacement of whisker contacted Schottky diodes for applications in the THz frequency range is an important topic of investigation. The recent status of planar Schottky diodes using the quasi-vertical approach is shown. Mixer diodes with anode diameters of 0.8 - 2 gm and cut-off frequencies up to 9 THz have been fabricated that offer characteristics comparable to whiskered diodes with the same diode parameters.
Basophil allergen threshold sensitivity, CD‐sens, IgE‐sensitization and DBPCFC in peanut‐sensitized children (2011)

In this study, a negative CD-sens to peanut excluded peanut allergy. Both tests, CD-sens to peanut and immunoassay for IgE-antibody to the peanut components, appear to be safe, time saving and cost-effective complements to DBPCFC.
Human HMGCS2 Regulates Mitochondrial Fatty Acid Oxidation and FGF21 Expression in HepG2 Cell Line (2011)

HMGCS2 (hydroxymethylglutaryl CoA synthase 2), the gene that regulates ketone body production, is barely expressed in cultured cell lines. In this study, we restored HMGCS2 expression and activity in HepG2 cells, thus showing that the wild type enzyme can induce fatty acid β-oxidation (FAO) and ketogenesis, whereas a catalytically inactive mutant C166A did not generate either process. Peroxisome proliferator-activated receptor (PPAR) α expression also induces fatty acid β-oxidation and endogenous HMGCS2 expression. Interestingly, PPARα-mediated induction was abolished when HMGCS2 expression was down-regulated by RNAi. These results indicate that HMGCS2 expression is both sufficient and necessary to the control of fatty acid oxidation in these cells. Next, we examined the expression pattern of several PPARα target genes in this now "ketogenic" HepG2 cell line. FGF21 (fibroblast growth factor 21) expression was specifically induced by HMGCS2 activity or by the inclusion of the oxidized form of ketone bodies (acetoacetate) in the culture medium. This effect was blunted by SirT1 (sirtuin 1) RNAi, so we propose a SirT1-dependent mechanism for FGF21 induction by acetoacetate. These data suggest a novel feed-forward mechanism by which HMGCS2 could regulate adaptive metabolic responses during fasting. This mechanism could be physiologically relevant, because fasting-mediated induction of liver FGF21 was dependent on SirT1 activity in vivo.
Assessing image‐based authentication techniques in a web‐based environment (2010)

The purpose of this paper is to assess the usability of two image-based authentication methods when used in the web-based environment. The evaluated approaches involve clicking secret points within a single image (click-based) and remembering a set of images in the correct sequence (choice-based). A “one-to-one” usability study was conducted in which participants had to complete three main tasks; namely authentication tasks (register, confirm and login), spot the difference activity and provide feedback. From analysing the results in terms of timing, number of attempts, user feedback, accuracy and predictability, it is found that the choice-based approach is better in terms of usability, whereas the click-based method performed better in terms of timing and is ratedmore secure against social engineering.The majority of participants are from the academic sector (students, lecturers, etc.) and had up to seven years’ IT experience. To obtain more statistically significant results, it is proposed that participants should be obtained from various sectors, having a more varied IT experience. The results suggest that in order for image-based authentication to be used in the web environment, more work is needed to increase the usability, while at the same time maintaining the security of both techniques. This paper enables a direct comparison of the usability of two alternative image-based techniques, with the studies using the same set of participants and the same set of environment settings.
Synthesis of the bi‐heterocyclic parent ring system 1,2,4‐triazolo[4,3‐<i>b</i>][1,2,4,5]tetrazine and some 3,6‐disubstituted derivatives (1998)

Abstract The synthesis of the previously unknown parent ring system was developed. Treatment of 3‐hydrazino‐1,2,4,5‐tetrazine ( 4 ) with diethoxymethyl acetate gave the parent ring system. Similar treatment of 3‐(3,5‐dimethylpyrazol‐1‐yl)‐6‐hydrazino‐1,2,4,5‐tetrazine ( 2 ) with one carbon cyclizing reagents gave 3,6‐di‐substituted derivatives of the 1,2,4‐triazolo‐1,2,4,5‐tetrazine ring system.
Efficient widely-separated optical parametric oscillation (2020)

We demonstrate the first widely-separated optical parametric oscillation in silicon nanophotonics, with milliwatt-level threshold power that is > 50 times smaller than other widely-separated OPOs. This demonstration is promising for on-chip visible light generation.
A copper-(.mu.2-hydrogen) bond can be stronger than an intramolecular phosphorus .fwdarw. copper bond. Synthesis and structure of di-.mu.-hydridobis[.eta.2-1,1,1-tris(diphenylphosphinomethyl)ethane]dicopper (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA copper-(.mu.2-hydrogen) bond can be stronger than an intramolecular phosphorus .fwdarw. copper bond. Synthesis and structure of di-.mu.-hydridobis[.eta.2-1,1,1-tris(diphenylphosphinomethyl)ethane]dicopperGary V. Goeden, John C. Huffman, and Kenneth G. CaultonCite this: Inorg. Chem. 1986, 25, 15, 2484–2485Publication Date (Print):July 1, 1986Publication History Published online1 May 2002Published inissue 1 July 1986https://pubs.acs.org/doi/10.1021/ic00235a002https://doi.org/10.1021/ic00235a002research-articleACS PublicationsRequest reuse permissionsArticle Views726Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
MHC Class I Alleles Influence Set-Point Viral Load and Survival Time in Simian Immunodeficiency Virus-Infected Rhesus Monkeys (2002)

In HIV-infected humans and SIV-infected rhesus macaques, host genes influence viral containment and hence the duration of the disease-free latency period. Our knowledge of the rhesus monkey immunogenetics, however, is limited. In this study, we describe partial cDNA sequences of five newly discovered rhesus macaque (Mamu) class I alleles and PCR-based typing techniques for the novel and previously published Mhc class I alleles. Using 15 primer pairs for PCR-based typing and DNA sequence analysis, we identified at least 21 Mhc class I alleles in a cohort of 91 SIV-infected macaques. The results confirm the presence of multiple class I genes in rhesus macaques. Of these alleles, Mamu-A*01 was significantly associated with lower set-point viral load and prolonged survival time. Mamu-A*1303 was associated with longer survival and a "novel" Mhc class I allele with lower set-point viral load. The alleles are frequent in rhesus macaques of Indian origin (12-22%). In addition, survival probability of individual SIV-infected rhesus monkeys increased with their number of alleles considered to be associated with longer survival. The results contribute to improve the interpretation and quality of preclinical studies in rhesus monkeys.
On the Development of a System for Gesture Control of Spatialization (2006)

This paper presents our current approach to the development of a system for controlling spatialization in a performance setup for small ensemble. We are developing a Gesture Description Interchange Format (GDIF) to standardize the way gesture-related information is stored and shared in a networked computer setup. Examples are given of our current GDIF namespace, the gesture tracking subsystem developed to use this namespace and patches written to control spatialization and mapping using gesture data. 1
Papyrus Prisse Line 168: Grammatical Analysis and Meaning (2008)

Abstract Papyrus Prisse line 168 can be best explained as the second tense construction conveying a hypothetical sense: “Should he (= man of character) seize, he would be like a crocodile in the court of magistrates.”
Improvement of Metabolic Performance of Hepatocytes Cultured In Vitro in a Packed-Bed Reactor for Use as a Bioartificial Liver (1998)

A packed-bed reactor using reticulated polyvinyl formal (PVF) resin as a support material is a useful configuration to achieve high density culture of hepatocytes for use as a bioartificial liver. The authors investigated the effects of oxygen concentrations of the culture medium on the metabolic performance of hepatocytes cultured in the reactor. A packed-bed reactor loaded with 250 PVF resin cubes (2 x 2 x 2 mm) was used. Hepatocytes obtained from male Wistar rats were inoculated into the reactor. Culture medium was perfused from the reservoir into the reactor through an oxygenator using a roller pump. Concentration of the dissolved oxygen in the medium was controlled by changing the gas mixture ratio supplied to the oxygenator. Hepatocytes cultured in the packed-bed reactor (cell density: 8.6 x 10(6) cells/cm3 PVF) under conditions of high dissolved oxygen concentrations ranging from 260 to 460 micromol/L showed 30% higher ammonium metabolic activity and 85% higher albumin secretion activity compared with those from the monolayer culture in the earlier culture stage (up to 2 days). However, low oxygen concentrations in the medium (<100 micromol/L) impaired activities of cultured hepatocytes.
Melatonin: Delirium (Postsurgical) (2013)

This Hospital Pharmacy feature is extracted from Off-Label Drug Facts,a publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration. This new guide to the literature enables the health care professional or clinician to quickly identify published studies on off-label uses and determine if a specific use is rational in a patient care scenario. References direct the reader to the full literature for more comprehensive information before patient care decisions are made. Direct questions or comments regarding Off-Label Drug Uses to jgeneral@kumc.edu.
In-Vitro of Measurement of Static Pressure Distribution in Synovial Joints—Part I: Tibial Surface of the Knee (1983)

In this first part of a two-part paper, the results of measurement of static pressure distribution on the tibial surface of the knee are presented. Results with intact menisci have been obtained from 18 specimens. Eight of these specimens were the subject of further measurements following medial meniscectomy. The study has been carried out at various flexion angles of the knee with the joint subjected to a compressive force, with or without an initial passive relative displacement between the joint members. The results indicate that a significant fraction of the joint compressive load is transmitted through the menisci and that total meniscectomy causes a drastic alteration in the pressure distribution on the tibial surface. Clinical implications of these results, in terms of post-meniscectomy degenerative changes and mechanism of meniscal lesions, have been discussed.
Materials Characterization of Feraheme/Ferumoxytol and Preliminary Evaluation of Its Potential for Magnetic Fluid Hyperthermia (2013)

Feraheme, is a recently FDA-cleared superparamagnetic iron oxide nanoparticle (SPION)-based MRI contrast agent that is also employed in the treatment of iron deficiency anemia. Feraheme nanoparticles have a hydrodynamic diameter of 30 nm and consist of iron oxide crystallites complexed with a low molecular weight, semi-synthetic carbohydrate. These features are attractive for other potential biomedical applications such as magnetic fluid hyperthermia (MFH), since the carboxylated polymer coating affords functionalization of the particle surface and the size allows for accumulation in highly vascularized tumors via the enhanced permeability and retention effect. This work presents morphological and magnetic characterization of Feraheme by transmission electron microscopy (TEM), Energy dispersive X-ray spectroscopy (EDX), and superconducting quantum interference device (SQUID) magnetometry. Additionally, the results of an initial evaluation of the suitability of Feraheme for MFH applications are described, and the data indicate the particles possess promising properties for this application.
Structural evolution and the capacity fade mechanism upon long-term cycling in Li-rich cathode material (2012)

High capacity Li-rich layered cathode Li(Li(0.2)Mn(0.54)Ni(0.13)Co(0.13))O(2) and doped one are investigated to understand mechanisms of capacity fade as well as voltage decrease upon long-term cycling. Detailed electrochemical analysis reveals a phase-separation-like behavior with increase in the cycle number, which is responsible for gradual reduction in discharge voltage. X-ray photoelectron spectroscopy (XPS), transmission electron microscope coupled with energy dispersive X-ray spectroscopy (TEM-EDS) and inductively coupled plasma emission spectrometry (ICP) analysis results show increase in valence of transition metals on the surface of powder at a fully discharged state in addition to surface dissolution of Ni, leading to rapid capacity loss. High resolution transmission electron microscopy (HR-TEM) shows a phase transformation from original layered structure into spinel-like nano-domains in local structure. Though such an unexpected structural change is unfavorable because of lower output voltage, it is observed to be beneficial for high-rate performance.
Molecular Identification and Phylogenetic Grouping of <i>Diaporthe phaseolorum</i> and <i>Phomopsis longicolla</i> Isolates from Soybean (1998)

ABSTRACT Diaporthe phaseolorum and Phomopsis longicolla isolates from soybean were examined using traditional mycological characteristics and molecular methods. Cultural characteristics including types of fruiting bodies and conidia were assessed for isolates collected from soybean stems and seeds. Cultures were identified as P. longicolla, D. phaseolorum var. caulivora, D. phaseolorum var. meridionalis, or D. phaseolorum var. sojae. Molecular markers for these groups were developed and analyzed using polymerase chain reaction restriction fragment length polymorphisms (PCR-RFLP) and DNA sequencing in the internal transcribed spacer (ITS) and the 5.8S ribosomal DNA. The ITS(4) and ITS(5) primers amplified PCR products for all isolates studied. Gel electrophoresis of undigested PCR products and DNA sequencing produced various fragment lengths including 604 bp for P. longicolla, 602 and 603 bp for D. phaseolorum var. caulivora, 603 bp for D. phaseolorum var. meridionalis, and from 597 to 609 bp for D. phaseolorum var. sojae. Digestion of these PCR products with enzymes AluI, HhaI, MseI, RsaI, and ScrFI resulted in distinct bands for identification of P. longicolla and the varieties of D. phaseolorum I. All P. longicolla, D. phaseolorum var. caulivora, and D. phaseolorum var. meridionalis isolates were distinguished using AluI and HhaI with RsaI or ScrFI. The banding patterns of D. phaseolorum var. sojae isolates were complex and were separated into 11 subgroups after digestion with AluI, HhaI, MseI, RsaI, and ScrFI. Phylogenetic analysis of 20 isolates of D. phaseolorum and P. longicolla based on the DNA sequence of the ITS region resolved six clades termed A, B, C, D, E, and F. Clade A included all sequenced D. phaseolorum var. caulivora isolates, two from Italy and one from the United States. Isolates in clade B were exclusively associated with D. phaseolorum var. meridionalis. Clades A and B formed a well-supported monophyletic group. Isolates in clades C, D, E, and F were morphologically defined as isolates of P. longicolla, D. phaseolorum var. sojae, and Diaporthe spp. The ITS sequences similarity of seven geographically diverse P. longi-colla isolates illustrated that P. longicolla isolates have a similar genetic background, with some affiliations to some D. phaseolorum var. sojae isolates. Morphological characteristics of the isolates along with the terminal clades of the ITS phylogeny suggest that P. longicolla is an individual species, D. phaseolorum var. caulivora and D. phaseolorum var. meridionalis are varieties of D. phaseolorum, and D. phaseolorum var. sojae is either several varieties of D. phaseolorum or possibly several distinct species.
Peripheral Venous Pressure as a Hemodynamic Variable in Neurosurgical Patients (2001)

In patients undergoing either elective craniotomy or complex spine surgery, peripheral venous pressure (PVP) trends correlated with central venous pressure (CVP) trends with a mean offset of 3 mm Hg (PVP > CVP). PVP trends provided equivalent physiological information to CVP trends in this subset of patients, especially during periods of hemodynamic instability. In addition, measurements made during a planned circulatory arrest support the hypothesis that PVP approximates mean systemic pressure (systemic arrest pressure), which is a direct index of patient volume status independent of cardiac or respiratory activity.