gebhart/patrepeval huggingface dataset:
Progesterone inhibits human endometrial cancer cell growth and invasiveness: down-regulation of cellular adhesion molecules through progesterone B receptors. (2002)

Progesterone is a critical steroid hormone that controls cell proliferation and differentiation in the female reproductive tract. Progesterone acts through two nuclear receptor isoforms, progesterone receptors A and B (PRA and PRB, respectively), each with unique cellular effects. Loss of PRB has recently been linked to the development of poorly differentiated endometrial tumors, a lethal form of cancer. To study the molecular effects of progesterone, progesterone receptors were introduced into Hec50co endometrial cancer cells by adenoviral vectors encoding either PRA or PRB. Progesterone induced the cyclin-dependent kinase inhibitors p21 and p27, thereby significantly reducing the percentage of proliferating cells. Cancer cell invasion was also markedly inhibited as measured by Matrigel invasion studies. Similarly, a differentiated, secretory phenotype was induced by progesterone in cells expressing PRB. However, replicative senescence was induced by progesterone only in cells expressing PRA. Expression array analysis followed by confirmatory semiquantitative reverse transcription-PCR experiments demonstrated a significant progesterone-dependent inhibition of expression of a cadre of cellular adhesion molecules, including fibronectin, integrin alpha3, integrin beta1, integrin beta3, and cadherin 6. The level of down-regulation of adhesion molecule expression was significantly greater in the presence of the B isoform, demonstrating that progesterone acts principally through B receptors to inhibit cancer cell invasiveness modulated by adhesion molecules.
Research on Cabin Integrated Equipment Based on GIS (2021)

Through the research on the principle of GIS gas insulated switchgear, a GIS-based cabin integrated equipment method is proposed. The insulation characteristics and engineering calculations of SF6 gas are analyzed, which provides a basis for the selection of 220kV and 110kV equipment. Analyzed the applicability of 220kV equipment selection of HGIS equipment and GIS equipment in modular substations. At the same time, it compared the floor area and other indicators, and finally decided to adopt the GIS plan, further optimize the product structure and layout, and improve space utilization It can reduce the equipment footprint and make the layout of the power distribution device more compact. Through the comparison and analysis of the main wiring types of the 110kV single bus three section and double bus wiring, it is found that there are three aspects of reliability, flexibility and economy. Single-bus three-section is better than double-bus wiring, so 110kV is determined to adopt single-bus three-section wiring. Under the premise of meeting the requirements for power supply safety, reliability, and flexibility, 110kV electrical main wiring is optimized to achieve The purpose of simplifying operation and maintenance procedures and saving investment.
Corrosion Resistance of Electrodeposited Zinc-Silica Composite Coated Steel (1993)

<div class="htmlview paragraph">Corrosion resistance of Zn-SiO<sub>2</sub> composite coated steel has been investigated both in the wet/dry cyclic corrosion test and in the accelerated atmospheric corrosion test (modified Volvo test). In this investigation, perforation corrosion test were carried out using cathodic electrocoated lapped-panel models. Zn-SiO<sub>2</sub> composite coated steel has shown good perforation resistance as well as good cosmetic corrosion resistance. Polarization measurements for the Zn-SiO<sub>2</sub> composite coating have indicated the inhibition of both anodic and cathodic reaction. The inhibition of these reactions becomes more marked as corrosion of the coating progresses. From the microstructural analysis of the coating after the corrosion tests, excellent corrosion resistance of Zn-SiO<sub>2</sub> composite coated steel is attributed to the chemically stable corrosion product consisting of zinc hydroxide and SiO<sub>2</sub> particles.</div>
A Retrospective Study of Patients Discharged within 24 Hours after Emergency Admission in a Public General Hospital (2002)

Objectives To identify the epidemiological characteristics and outcome of patients who were discharged within 24 hours of emergency admission, and to explore methods to reduce inappropriate admission. Design Retrospective study. Setting Emergency admission in a public general hospital in Hong Kong. Patients Four hundred and ninety-one cases collected in a three-month period from 1st April 2000 to 30th June 2000, excluding those who died within 24 hours of admission. Main outcome measures Patients' epidemiological and clinical characteristics, specialty of admission, in-patient procedures performed, diagnosis upon discharge and destination of patients. Results During the study period, 8.8% of the 5,587 emergency admissions were discharged within 24 hours. Most of them were middle-aged males, triaged as category 3 and 4 non-trauma cases. The percentage of emergency Orthopaedic and Surgical admission resulting in discharge within 24 hours was 18.5% and 16.2% respectively, substantially higher than the percentage of emergency Medical and Paediatric admission (5.5% and 4.7% respectively). The most common diagnoses included orthopaedic open soft tissue injuries, orthopaedic closed fractures and dislocations, head injury, drug overdose, abdominal pain, ischaemic heart disease or chest pain and foreign body in throat. Overall, 20.8% of cases received some forms of orthopaedic procedures, 9% had computed tomography (CT) brain done, and 5.5% had OGD performed. Around 90% of cases with orthopaedic open soft tissue injuries and closed fractures or dislocations received intervention, 73% of head injury cases had CT brain done, and around 63% of patients with foreign body in throat received oesophago-gastroduodenoscopy (OGD). Overall, 14% of cases discharged themselves against medical advice or walked away after admission. Up to 9.8% were transferred to other hospitals within 24 hours. Around 54.8% were followed up in hospital after discharge, and re-admission was planned in 2.9% for elective procedures. Only 13 cases (2.6%) were re-admitted through A&E within one week with the same diagnosis into the same specialty. Conclusions The issue of ‘discharge within 24 hours’ should not automatically be regarded as inappropriate emergency admission. Upgrade of professional training and clinical supervision, improvement of administrative arrangement and clinical audit are possible measures to enhance the efficiency of hospital utilization.
Preparation of Silver Nanoparticles Using a Spinning Disk Reactor in a Continuous Mode (2009)

A spinning disk reactor (SDR) operated in a continuous mode was adopted for producing silver nanoparticles, aiming at an increase in the production rate. Two protecting agents, i.e., poly(vinylpyrrolidone) (PVP) and hydroxypropylmethyl cellulose (HPMC), were tested, which have been proven to be effective in our previous work of recycle operation. Using PVP as protecting agent, the effects of the operating variables, including the rotation speed, the feeding rate, the dosage of protecting agent, and reactant concentration, on the particle size and yield of the silver product were investigated. The experiment was further conducted using HPMC as protecting agent to compare the experimental results between the two protecting agents. The use of PVP gave smaller silver nanoparticles; however, a higher yield was obtained by using HPMC. Although the yield of continuous operation was lower than that of recycle operation, the production rate was much higher for either protecting agent, providing a great potential for commercialization.
Preparation of 1-α-D-Arabinofuranosylbenzimidazole and Its 5,6-Dichloro Derivative, and the Direct Bromination of Benzimidazole Nucleosides (1980)

Abstract Arabinofuranosyl Benzim idazole N ucleosides, Direct Bromination of Benzim idazole N ucleosides, 1 H NMR Spectroscopy, Ultraviolet Spectra The 1-a-D-arabinofuranosides of benzim idazole and 5,6-dichlorobenzim idazole, analogues of the biologically active 5,6-dichloro-l-β-D-ribofuranosylbenzimidazole, have been synthesized by condensation of the trimethylsilyl derivative of the appropriate benzim idazole in the presence of SnCl 4 with 1-O-m ethyl-2,3,5-tribenzoyl-a-D-arabinoside. The 5(6)-m onobrom o and the 5,6-dibrom o derivatives of 1-β-D-ribofuranosylbenzimidazole and 1-α-D-arabinofuranosylbenzimidazole were then prepared by direct bromination of the latter. With 1-β-D-ribofuranosylbenzimidazole, the initial product of bromination was a 1:1 mixture of the 5-bromo and 6 -brom o derivatives; the final product was the desired 5,6-dibromo analogue. In the case of 1-αβ-D-arabinofuranosylbenzimidazole, the initial product of bromination was the 5-(or 6 -)brom o derivative, and the 5,6-dibrom o derivative the final product. The monobrom o derivatives were easily separated from the dibrom o by chromatography on Am berlite XAD-4. Identification of all of these was based on several criteria, including detailed analyses of the 1 H NMR spectra. The benzim idazole nucleoside are considerably m ore resistant to acid hydrolysis than the cor­ responding purine nucleosides. The effects of halogenation on the ultraviolet absorption spectra of the benzim idazole nucleosides are described.
Reverse engineering of binary device drivers with RevNIC (2010)

This paper presents a technique that helps automate the reverse engineering of device drivers. It takes a closed-source binary driver, automatically reverse engineers the driver's logic, and synthesizes new device driver code that implements the exact same hardware protocol as the original driver. This code can be targeted at the same or a different OS. No vendor documentation or source code is required. Drivers are often proprietary and available for only one or two operating systems, thus restricting the range of device support on all other OSes. Restricted device support leads to low market viability of new OSes and hampers OS researchers in their efforts to make their ideas available to the 'real world.' Reverse engineering can help automate the porting of drivers, as well as produce replacement drivers with fewer bugs and fewer security vulnerabilities. Our technique is embodied in RevNIC, a tool for reverse engineering network drivers. We use RevNIC to reverse engineer four proprietary Windows drivers and port them to four different OSes, both for PCs and embedded systems. The synthesized network drivers deliver performance nearly identical to that of the original drivers.
Andrés Galdeano: Ceramista y pintor (2013)

espanolEste articulo esta dedicado a un artista de gran personalidad, provocador e independiente que vive en Zaragoza desde el ano 1959 hasta su muerte en el 2004. Entre 1967 y 1971 funda y dirige la Sala de Exposiciones Galdeano, que se caracterizo por exponer a muy destacados artistas espanoles, dentro de cambiantes tendencias abstractas. Su evolucion artistica comienza con una breve fase como pintor pero muy pronto encuentra en la ceramica su engranaje con la creatividad a traves del expresionismo abstracto. Autor de grandes murales en espacios publicos de Nueva York, Austria y Espana entre 1965 y 1983, abandona la ceramica para consagrarse a la pintura entre 1983 y 2004 con el expresionismo abstracto como tendencia artistica y, en ocasiones, la incorporacion de rostros sobre grandes literatos y filosofos espanoles, dos de sus pasiones como gran lector EnglishThis paper is devoted to an artist of great personality, provocative and independent who lived in Zaragoza since 1959 until his death in 2004. In 1967 he founded Galdeano Art Gallery, which he would run until 1971, a space exhibiting very prominent Spanish artists, of changing abstract trends. His artistic evolution begins with a brief phase as a painter but soon he found in ceramics his gear with creativity through Abstract Expressionism. Author of large murals in public spaces in New York, Austria and Spain between 1965 and 1983, he abandons ceramics in 1983 to devote itself to painting up to 2004 with Abstract Expressionism as artistic tendency with, occasionally, the incorporation of portraits of great Spanish writers and philosophers, two of his passions as a great reader.
A SDN-oriented DDoS blocking scheme for botnet-based attacks (2014)

DDoS attacks mounted by botnets today target a specific service, mobilizing only a small amount of legitimate-looking traffic to compromise the server. Detecting or blocking such clever attacks by only using anomalous traffic statistics has become difficult, and devising countermeasures has been mostly left to the victim server. In this paper, we investigate how a software-defined network (SDN) can be utilized to overcome the difficulty and effectively block legitimate looking DDoS attacks mounted by a larger number of bots. Specifically, we discuss a DDoS blocking application that runs over the SDN controller while using the standard OpenFlow interface.
Isolation and characterization of a conserved porin protein from Helicobacter pylori (1995)

Helicobacter pylori is a causative agent of gastritis in humans and is correlated with gastric ulcer formation. Infections with this bacterium have proven difficult to treat with antimicrobial agents. To better understand how this bacterium transports compounds such as antimicrobial agents across its outer membrane, identification of porin proteins is important. We have recently identified a family of H. pylori porins (HopA to HopD) (M. M. Exner, P. Doig, T. J. Trust, and R. E. W. Hancock, Infect. Immun. 63:1567-1572, 1995). Here, we report on an unrelated porin species (HopE) from this bacterium. This protein had a apparent molecular mass of 31 kDa and was seen to form 50- and 90-kDa aggregates that were designated putative dimeric and trimeric forms, respectively. The protein was purified to homogeneity and, with a model planar lipid membrane system, was shown to act as a nonselective pore with a single channel conductance in 1.0 M KCl of 1.5 nS, similarly to other bacterial nonspecific porins. An internal peptide sequence of HopE shared homology with the P2 porin of Haemophilus influenzae. HopE was also shown to be antigenic in vivo as assessed by sera taken from H. pylori-infected individuals and was immunologically conserved with both patient sera and specific monoclonal antibodies. From these data, it appears that HopE is a major nonselective porin of H. pylori. The implications of these findings are discussed.
The Future Digital Work Force: Robotic Process Automation (RPA) (2019)

The Robotic Process Automation (RPA) is a new wave of future technologies. Robotic Process Automation is one of the most advanced technologies in the area of computers science, electronic and communications, mechanical engineering, and information technology. It is a combination of both hardware and software, networking and automation for doing things very simple. In this light, the research manuscript investigated the secondary data - which is available on google, academic and research databases. The investigation went for totally 6 months, i.e., 1-1-2018 to 30-6-2018. A very few empirical articles, white papers, blogs and were found RPA and came across to compose this research manuscript. This study is exploratory in nature because of the contemporary phenomenon. The keywords used in searching of the database were Robotic Process Automation, RPA, Robots, Artificial Intelligence, Blue Prism. The study finally discovered that Robots and Robotic Process Automation technologies are becoming compulsory as a part to do business operations in organizations across the globe. Robotic Process Automation can bring immediate value to the core business processes including employee payroll, employee status changes, new hire recruitment, and onboarding, accounts receivable and payable, invoice processing, inventory management, report creation, software installations, data migration, and vendor onboarding etc. to name a few applications. Besides, the Robotic Process Automation has abundant applications including healthcare and pharmaceuticals, financial services, outsourcing, retail, telecom, energy and utilities, real estate and FMCG and many more sectors. To put in the right place of RPA in business operations, their many allied technologies are working at the background level, artificial intelligence, machine learning, deep learning, data analytics, HR analytics, virtual reality (second life), home automation, blockchain technologies, 4D printing etc. Moreover, it covers the content of different start-ups companies and existing companies - their RPA applications used across the world. This manuscript will be a good guideline for the academicians, researchers, students, and practitioners to get an overall idea.
NEW TYPE OF HIGH-FREQUENCY MASS SPECTROMETER WITH TWO ELECTRODES (1966)

Mitotic counting is often used for classification, grading and prognosis of tumors. The count usually stands as a decision point for treatment as well. The easiest way of counting the number of mitoses is done by screening routine H&E stained slides. However, for proper mitotic counting, certain strict protocols should be taken into consideration. This study on 30 cases of different grades of oral squamous cell carcinoma was undertaken to determine the interobserver variations in two different groups: Group1 (A1, A2), who were given certain criteria to be followed during the counting of the mitotic figures and group 2 investigators (B1, B2) who were unaware of such criteria. The paired t-test gives a correlation of 0.988 and a significant difference of 0.000 between the two investigators in group 1. The correlation was 0.650 with a significant difference of 0.058 between two investigators in-group 2, indicating that group 1 observers exhibit good interobserver agreement. The results emphasize that following of strict protocols are of great help in determining the accuracy of mitotic counting.
Velocity models from wide-angle seismic data by wavefield inversion (1994)

Conventional surface-seismic reflection geometries are optimally designed to image sub-horizontal structure in a stratified earth. With this geometry traveltimes, raypaths, waveforms and amplitudes are minimally distorted by macro-velocity variations. By the same token, conventional reflection geometries are not optimal if velocity determination is the primary aim. In this case a geometry is required for which traveltimes, raypaths and waveforms are maximally distorted by velocity variations. Geometries which include wide-angle reflections and post-critical turning rays, provide such an opportunity.
Network Position and Cognition in a Computer Software Firm (1985)

Gordon Walker The present study examined the relationship between differences in cognition among the members of a software firm and the position a member occupied in the network of task relationships in the organization. Cognition was measured through judgments about means-ends associations relevant to software product success. The network was analyzed as a blockmodel, and positions in the network were defined as blocks of structurally equivalent individuals. Network position was found to be a stronger and more stable predictor of differences in cognition than the type of function an individual had and the type of product worked on. Both tenure in the industry and tenure in the firm also were found to have strong and stable effects. The generalizability of the findings is discussed in terms of the type of cognition studied and the firm's size, technology, and level of market uncertainty.*
Hydrozirconation of Stannylacetylenes:  A Novel and Highly Efficient Synthesis of 1,1-Diiodo-, 1,1-Dibromo-, and Mixed (<i>Z</i>)- or (<i>E</i>)-1-Iodo-1-bromo-1-alkenes Using 1,1-Hetero-Bimetallic Reagents (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTHydrozirconation of Stannylacetylenes: A Novel and Highly Efficient Synthesis of 1,1-Diiodo-, 1,1-Dibromo-, and Mixed (Z)- or (E)-1-Iodo-1-bromo-1-alkenes Using 1,1-Hetero-Bimetallic ReagentsMiguel J. Dabdoub, Vânia B. Dabdoub, and Adriano C. M. BaroniView Author Information Laboratório de Síntese de Compostos Organocalcogênios Departamento de Química - FFCLRP Universidade de São Paulo, Av. Bandeirantes, 3900 Ribeirão Preto, São Paulo, Brazil Cite this: J. Am. Chem. Soc. 2001, 123, 39, 9694–9695Publication Date (Web):September 7, 2001Publication History Received14 June 2001Published online7 September 2001Published inissue 1 October 2001https://pubs.acs.org/doi/10.1021/ja0114660https://doi.org/10.1021/ja0114660rapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views1345Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information SUBJECTS:Anions,Chemical reactions,Hydrocarbons,Molecular structure,Reagents Get e-Alerts
Emergency and microfog lubrication and cooling of bearings for Army helicopters (1978)

An analysis and system study was performed to provide design information regarding lubricant and coolant flow rates and flow paths for effective utilization of the lubricant and coolant in a once-through oil-mist (microfog) and coolant air system. A system was designed, manufactured, coupled with an existing rig and evaluation tests were performed using 46 mm bore split-inner angular-contact ball bearings under 1779N (400 lb.) thrust load. An emergency lubrication aspirator system was also manufactured and tested under lost lubricant conditions. The testing demonstrated the feasibility of using a mist oil and cooling air system to lubricate and cool a high speed helicopter engine mainshaft bearing. The testing also demonstrated the feasibility of using an emergency aspirator lubrication system as a viable survivability concept for helicopter mainshaft engine bearing for periods as long as 30 minutes.
Basic principles of thermal degradation and thermal stabilization of poly(vinyl chloride). Mathematical model of the action of PVC thermal stabilizers (1977)

Abstract A model of the action of chemically homogeneous thermal stabilizers of poly(vinyl chloride) is shown. Based on the described computer program and experimental data, the proposed model is confirmed and rate constants of the reaction of stabilizers with HCI and the effect of the products of this reaction on the kinetics of PVC degradation are calculated.