gebhart/patrepeval huggingface dataset:
Experimental investigation of the liquid volumetric mass transfer coefficient for upward gas-liquid two-phase flow in rectangular microchannels (2010)

The gas-liquid two-phase mass transfer process in microchannels is complicated due to the special dynamical characteristics. In this work, a novel method was explored to measure the liquid side volumetric mass transfer coefficient kLa. Pressure transducers were utilized to measure the pressure variation of upward gas-liquid two-phase flow in three vertical rectangular microchannels and the liquid side volumetric mass transfer coefficient kLa was calculated through the Pressure-Volume-Temperature correlation of the gas phase. Carbon dioxide-water, carbon dioxide-ethanol and carbon dioxide-n-propanol were used as working fluids, respectively. The dimensions of the microchannels were 40 µm×240 µm (depth×width), 100 µm×800 µm and 100 µm×2000 µm, respectively. Results showed that the channel diameter and the capillary number influence kLa remarkably and that the maximum value of kLa occurs in the annular flow regime. A new correlation of kLa was proposed based on the Sherwood number, Schmidt number and the capillary number. The predicted values of kLa agreed well with the experimental data.
Corin Overexpression Improves Cardiac Function, Heart Failure, and Survival in Mice With Dilated Cardiomyopathy (2012)

Heart failure, caused by dilated cardiomyopathy and other cardiac disorders such as hypertension, is a major public health problem with high morbidity and mortality. Corin, a cardiac enzyme that cleaves natriuretic peptides, is a promising biomarker of cardiomyopathy and heart failure, but its functional role in these processes is not understood. We evaluated the potential effects of corin in mice with a well-characterized model of dilated cardiomyopathy. Mice with dilated cardiomyopathy developed heart failure, reduced contractile function, cardiac fibrosis, and accelerated mortality in the setting of low corin expression. In wild-type mice, transgenic, cardiac-targeted, overexpression of corin enhanced cyclic guanosine monophosphate and blood pressure responses to pro-atrial natriuretic peptide, but did not affect heart size, contractility, body weights, survival, and blood pressure. In mice with dilated cardiomyopathy, corin overexpression significantly reduced the development of myocardial fibrosis (P<0.05). Corin overexpression also enhanced heart contractile function (fractional shortening and ejection fraction; P<0.01) and it significantly reduced heart failure as assessed by lung water (P<0.05) and alveolar congestion (P<0.001). Consistent with these observations, corin overexpression significantly prolonged life in mice with dilated cardiomyopathy (P<0.0001). These results provide the first experimental evidence that corin expression plays a role in cardiomyopathy by modulating myocardial fibrosis, cardiac function, heart failure, and survival.
Online algorithms for selective multicast and maximal dense trees (1997)

Article Online algorithms for selective multicast and maximal dense trees Share on Authors: Baruch Awerbuch Dept. of Computer Science, Johns Hopkins University Dept. of Computer Science, Johns Hopkins UniversityView Profile , Tripurari Singh Dept. of Computer Science, Johns Hopkins University Dept. of Computer Science, Johns Hopkins UniversityView Profile Authors Info & Claims STOC '97: Proceedings of the twenty-ninth annual ACM symposium on Theory of computingMay 1997 Pages 354–362https://doi.org/10.1145/258533.258619Online:04 May 1997Publication History 10citation275DownloadsMetricsTotal Citations10Total Downloads275Last 12 Months8Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Press-fit fixation using autologous bone in the tibial canal causes less enlargement of bone tunnel diameter in ACL reconstruction - a CT scan analysis three months postoperatively (2015)

This study demonstrates that press-fit fixation with free autologous bone plugs in the tibial tunnel results in significantly smaller diameter of the tibial tunnel compared to interference screw fixation.
Fabrication of Perfusable Pseudo Blood Vessels by Controlling Sol–Gel Transition of Gellan Gum Templates (2019)

Construction of three-dimensional (3D) tissues with perfusable vascular networks remains a major challenge in the field of tissue engineering. Although various sacrificial templates have been employed to fabricate the vascular networks, there are some issues with respect to cytocompatibility, structural controllability, and degradability for the achievement of precisely controlled vasculatures without cytotoxicity. Here, we demonstrate a naturally occurring polysaccharide, gellan gum (GG), as a sacrificial template material due to its unique character. GG showed rapid gelation at 30-50 °C during the cooling process depending on the concentration of bivalent calcium ions by intermolecular ionic cross-linking and subsequent double-helix formation of GG molecules. Although chelate agents such as EDTA are generally effective in decomposing ionic cross-linking gels, e.g., alginate gel, they usually show cytotoxicity. In the case of GG gel, the gels could not be decomposed by the chelate agents but were easily decomposed by Tris-HCl buffer (pH = 7.4), which is a basic molecule with high cytocompatibility. We finally fabricated straight vascular tubes in 3D-gelatin gels and then demonstrated perfusion of human whole blood at 3.0 cm/s for 2 h. Since the complex vascular networks were constructed by 3D inkjet printing of the GG solution, GG would be useful as a structurally controllable and easily decomposable sacrificial material with cytocompatibility.
RETRO-DIRECTIVE BEAMFORMING VERSUS RETRO-REFLECTIVE BEAMFORMING WITH APPLICATIONS IN WIRELESS POWER TRANSMISSION (2016)

This paper studies the difference between retro-directive beamforming technique and retroreflective beamforming technique in the context of wireless power transmission applications. In all of our studies, a wireless power receiver broadcasts continuous-wave pilot signal; the wireless power transmitter receives and analyzes the pilot signal; finally, the wireless power transmitter transmits continuous-wave power with phase profile conjugate to that of the received pilot signal. Our study demonstrates that a linear equi-spaced antenna array configuration employed by the wireless power transmitter behaves as a retro-directive beamformer when the wireless power receiver resides in the far-zone of the wireless power transmitter, whereas it behaves as a retro-reflective beamformer when the wireless power receiver is not in the far-zone. This paper further investigates two types of array configurations other than linear equi-spaced array when the wireless power transmitter behaves as a retro-reflective beamformer. One is a V-shaped array, which is obtained by deforming the linear equi-spaced array to a "V" shape. The other is termed "perturbed array:" on the basis of linear equi-spaced array, all the elements' locations are perturbed randomly. It is particularly interesting to compare the equi-spaced array and perturbed array. When the wireless power receiver resides 5 or 6 wavelengths away, a 6-element equi-spaced array and a 6-element perturbed array produce the same power level at the near-zone focal point, but the maximum far-zone gain associated with the perturbed array is 1 dB lower than the equi-spaced array. All the conclusions drawn in this paper are supported by numerical results as well as experimental results.
High capacitance ultra-thin Ta<inf>2</inf>O<inf>5</inf>dielectric film applied to a high-speed bipolar memory cell (1985)

A new capacitor technology, with extremely thin Ta <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</inf> film deposition and weakspot oxidation, is developed to realize high capacitance and high reliability. The Ta <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</inf> film was reactively sputtered and followed by the weakspot oxidation. The oxidation improves the breakdown voltage by selectively oxidizing Si surface at weakspots where Ta <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</inf> is locally thin. Consequently it reduces the defect density of the Ta <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</inf> capacitor with least reduction of capacitance. This technology is based on a newly discovered fact that Ta <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</inf> film below 200 Å remains in amorphous state with high dielectric breakdown strength even after heat treatments up to 1000 °C. Application of the Ta <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</inf> capacitor to a switched-load resistor memory makes it possible to reduce the memory cell area to one third that of a conventional one. The memory provides high speed operation, and has sufficient soft error immunity.
Usual Interstitial Pneumonia (1997)

RATIONALE AND OBJECTIVES The authors developed a texture-based pattern recognition and segmentation tool for the quantitation of high-resolution computed tomography(HRCT) findings in usual interstitial pneumonia (UIP). METHODS In HRCT images of five patients with UIP and five patients without UIP, 1022 regions of interest (ROIs) of 5 x 5 pixels were classified by the examiner to be normal, emphysematous, ground-glass lesion, intralobular fibrosis, vessel, or bronchus section. The classes and the texture parameters calculated in the ROIs were the basis for the decision rule, using a multivariate discrimination analysis. The classification was compared with the examiner's diagnosis in 1889 new randomly selected ROIs. RESULTS Depending on the structure, the sensitivity (the probability that a structure would be recognized correctly) was 68.7% to 80.7%. If the system classified a structure as normal, ground glass or fibrotic region, this was correct in 77.3% to 88.1%. However, the system's diagnosis of a bronchus section was correct in only 16.2%. The overall accuracy was 70.7%. CONCLUSIONS Texture-based segmentation may be a valuable tool to aid the quantitative assessment of parenchymal disease in HRCT images.
Radix-16 signed-digit division (1990)

A two-stage algorithm for fixed point, radix-16 signed-digit division is presented. The algorithm uses two limited precision radix-4 quotient digit selection stages to produce the full radix-16 quotient digit. The algorithm requires a two-digit estimate of the (initial) partial remainder and a three-digit estimate of the divisor to correctly select each successive quotient digit. The normalization of redundant signed-digit numbers requires accommodation of some fuzziness at one end of the range of numeric values that are considered normalized. A set of general equations for determining the ranges of normalized signed-digit numbers is derived. Another set of general equations for determining the precisions of estimates of the divisor and dividend are derived. These two sets of equations permit design tradeoff analyses to be made with respect to the complexity of the model division. The specific case of a two-stage radix-16 signed-digit division is presented. The staged division algorithm used can be extended to other radices as long as the signed-digital number representation used has certain properties.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Coexpression of Vascular Endothelial Growth Factor and Interleukin-1 Receptor Antagonist for Improved Human Islet Survival and Function (2007)

Ex vivo gene therapy approaches can improve the outcome of islet transplantation for treating type I diabetes. We have recently shown improvement in islet survival and function following ex vivo infection of islets with a mixture of adenoviral vectors encoding human vascular endothelial growth factor (Adv-hVEGF) and human interleukin-1 receptor antagonist (Adv-hIL-1Ra). In this study, we constructed a bicistronic vector encoding these two genes (phVEGF-hIL-1Ra) by cloning hIL-1Ra under the cytomegalovirus (CMV) promoter and hVEGF under the elongation factor-1alpha (EF-1 alpha) promoter in pBudCE4.1 vector. There was dose and time dependent expression of hVEGF and hIL-1Ra at both mRNA and protein levels after transfection with human islets. Transfected islets were viable, as evidenced by insulin release upon glucose challenge. Coexpression of hVEGF and hIL-1Ra suppressed nitric oxide production, total caspases, apoptosis, and necrosis in the presence of inflammatory cytokine cocktail consisting of IL-1beta, TNFalpha, and IFNgamma. In conclusion, our results indicated that coexpression of growth factor and antiapoptic genes can improve islet survival and function.
Preliminary investigation of Candida albicans biovars (1983)

A total of 126 Candida albicans strains were enzymatically evaluated by the API ZYM system. Four enzymatically based groups of C. albicans are recognized.
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS (2012)

Amyotrophic lateral sclerosis (ALS) is a progressive disease associated with neuronal cell death that is thought to involve aberrant immune responses. Here we investigated the role of innate immunity in a mouse model of ALS. We found that inflammatory monocytes were activated and that their progressive recruitment to the spinal cord, but not brain, correlated with neuronal loss. We also found a decrease in resident microglia in the spinal cord with disease progression. Prior to disease onset, splenic Ly6Chi monocytes expressed a polarized macrophage phenotype (M1 signature), which included increased levels of chemokine receptor CCR2. As disease onset neared, microglia expressed increased CCL2 and other chemotaxis-associated molecules, which led to the recruitment of monocytes to the CNS by spinal cord-derived microglia. Treatment with anti-Ly6C mAb modulated the Ly6Chi monocyte cytokine profile, reduced monocyte recruitment to the spinal cord, diminished neuronal loss, and extended survival. In humans with ALS, the analogous monocytes (CD14+CD16-) exhibited an ALS-specific microRNA inflammatory signature similar to that observed in the ALS mouse model, linking the animal model and the human disease. Thus, the profile of monocytes in ALS patients may serve as a biomarker for disease stage or progression. Our results suggest that recruitment of inflammatory monocytes plays an important role in disease progression and that modulation of these cells is a potential therapeutic approach.
Bayesian Optimization in a Billion Dimensions via Random Embeddings (2016)

Bayesian optimization techniques have been successfully applied to robotics, planning, sensor placement, recommendation, advertising, intelligent user interfaces and automatic algorithm configuration. Despite these successes, the approach is restricted to problems of moderate dimension, and several workshops on Bayesian optimization have identified its scaling to high-dimensions as one of the holy grails of the field. In this paper, we introduce a novel random embedding idea to attack this problem. The resulting Random EMbedding Bayesian Optimization (REMBO) algorithm is very simple, has important invariance properties, and applies to domains with both categorical and continuous variables. We present a thorough theoretical analysis of REMBO. Empirical results confirm that REMBO can effectively solve problems with billions of dimensions, provided the intrinsic dimensionality is low. They also show that REMBO achieves state-of-the-art performance in optimizing the 47 discrete parameters of a popular mixed integer linear programming solver.
Effect of traditional food processing methods on the nutritional value of yams in Cameroon (1981)

We studied changes of energetic value and chemical composition (moisture, raw fibre, proteins, fat, total carbohydrates, ashes, calcium, phosphorus, iron, thiamine, riboflavin, niacin) of the tubers of Dioscorea dumetorum, D. rotundata, D. cayenensis, and D. schimperiana during traditional processing (peeling, boiling, charcoal grilling, frying, and preparation of fufu, flour, or biscuit) and found that cooking in boiling water with the peel and frying are the processes that best preserve the chief nutrients. Grilling and preparation of biscuit result in the largest losses.
The SWISS-PROT protein sequence data bank (1991)

Journal Article The SWISS-PROT protein sequence data bank Get access Amos Bairoch, Amos Bairoch Department of Medical Biochemistry, University of Geneva1 rue Michel Servet, 1211 Geneva 4, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Brigitte Boeckmann Brigitte Boeckmann 1European Molecular Biology LaboratoryHeidelberg, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 19, Issue suppl, 25 April 1991, Pages 2247–2249, https://doi.org/10.1093/nar/19.suppl.2247 Published: 25 April 1991
High Sensitivity, One-Sided X-Ray Inspection System. (1985)

A backscatter x-ray imaging method for nondestructive testing has been developed. The one-sided inspection technique, a slot camera, is much faster in response than previous backscatter methods. Delaminations in graphite-epoxy composites and other low atomic number materials have been detected. Wall thicknesses up to 7 cm thick have been interrogated. The results show the location (depth) and magnitude (separation width) of simulated delaminations throughout the entire wall. A disbond between two flat surfaces in contact has been detected. Feasibility of the system has been shown with film detectors. A fastresponse electronic detector is proposed. The objective of this program was to demonstrate the feasibility of an x-ray inspection equipment capable of probing an inspection sample from only one side to detect delaminations, voids, cracks or foreign material through the thickness interrogated. The feasibility of a unique, patented x-ray slot camera that works by scattered radiation was demonstrated using film techniques. The unique capability of this slot camera is that it can obtain images of the internal structure of an object at depths of many centimeters (depending on the object density and the x-ray energy) with a sensitivity that is several orders of magnitude greater than past-developed scattered radiation cameras.
ChemInform Abstract: Structure Activity Relationships of 2‐Phenylpyrazolo(4,3‐c)quinolin‐3‐ ones and Their N‐ and O‐Methyl Analogues at Benzodiazepine Receptors. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Yolk Fatty Acid Composition and Cholesterol Content in Response to Level and Form of Dietary Flaxseed (1998)

The effect of the level and form of dietary flaxseed on the fatty acid composition and cholesterol content of hen egg has been investigated. Dietary flaxseed notably altered yolk fatty acid composition by increasing total polyunsaturated fatty acids while decreasing monounsaturated fatty acids. α-Linolenic acid was linearly increased in response to levels of ground flaxseed, but whole flaxseed resulted in reduced α-linolenic acid availability for yolk deposition. Similar deposition profiles were exhibited by docosapentaenoic and docosahexaenoic acids. These alterations in yolk composition resulted in n−6 to n−3 fatty acid ratio values as low as 2.92 and 1.94 for 5 and 10% ground flaxseed and 2.49 for 10% whole flaxseed feeding, respectively. Dietary flaxseed had no effect on the cholesterol level of eggs, which showed a mean value of 188 mg/egg or 1247 mg/100 g of yolk. Keywords: Flaxseed; cholesterol; n−3 fatty acids; yolk; egg
Aberrant DNA Methylation of OLIG1, a Novel Prognostic Factor in Non-Small Cell Lung Cancer (2007)

Multivariate analyses of our data confirmed that OLIG1 protein expression significantly correlates with overall survival in NSCLC patients, with a relative risk of 0.84 (95% confidence interval 0.77-0.91, p < 0.001) along with T and N stages, as indicated by a Cox proportional hazard model. Taken together, our results suggests that OLIG1 protein expression could be utilized as a novel prognostic factor, which could aid in deciding which NSCLC patients might benefit from more aggressive therapy. This is potentially of great significance, as the addition of postoperative adjuvant chemotherapy in T2N0 NSCLC patients is still controversial.
The Existence Theorem (2009)

k is an algebraically closed field. This chapter is devoted to the proof of the following existence theorem.
Nonblocking DRAM Refresh (2019)

Since its invention half a century ago, dynamic random access memory (DRAM) has required dynamic refresh operations that block read accesses to refreshing data; this fundamental behavior gave DRAM its name. In contrast, DRAM's close relative—static random access memory (SRAM)—can statically re-enforce charge in the background without blocking read accesses at the cost of more expensive circuit structure. Nonblocking DRAM Refresh blurs this fundamental distinction between DRAM and SRAM at the system level to enable the best of both worlds—allowing read accesses to refreshing data in DRAM while preserving DRAM's low-cost circuit structure.
Perceptual segmentation and component selection in compact sinusoidal representations of audio (2002)

This paper presents two fundamental enhancements in a hybrid audio signal model consisting of sinusoidal, transient, and noise (STN) components. The first enhancement involves a novel application of a perceptual metric for optimal time segmentation for the analysis of transients. In particular, Moore and Glasberg's model of partial loudness is modified for use with general signals and then integrated into a, novel time segmentation scheme. The second and perhaps more significant STN enhancement is concerned with a new methodology for ranking and selection of the most perceptually relevant sinusoids.
Properties of SiC based electro-conductive ceramic composites. (1985)

高融点化合物の導電性とSiCの強度, 耐酸化性を生かして, 金属なみの導電性と優れた耐酸化性及び強度を併せ持つ複合材の開発を図った. SiCとTiC, ZrC, WC, ZrB2, TiB2, HfB2, NbB2, TaB2及びTiNのそれぞれとを体積率で50%ずつ混合し, ホットプレス焼結した. SiC-ZrC又はWC系以外は, 相対密度96%以上にち密に焼結した. これらの複合焼結体の抵抗率は室温で10-4Ω・cm前後であり, Ni-Cr合金と同等の導電性を持つ. 曲げ強さは, SiC単味焼結体の値に比し同等ないし1/2の値である. SiCとZrB2, TiB2, HfB2又はTaB2を複合化したものは特に耐酸化性に優れ, 1100℃の大気中で100h保持後の酸化増量は, 金属で最も耐酸化性のあるCo-32% Cr合金系の場合と同等である. 複合焼結体は, SiCと高融点化合物が互いに分散した微構造を持つ. 複合材は成分の高融点化合物の約4倍の抵抗率を持ち, 導電機構は導電率の異なる2種の粒子が均一混合した系のモデルで説明される. また, 焼結体内部への酸化の進行が抑制される.