gebhart/patrepeval huggingface dataset:
Effects of various emulsification methods on the oxidation of methyl linoleate (2014)

The effects of mechanical stress during emulsification on the oxidation of methyl linoleate were investigated by four methods (high-pressure homogenization, high-speed stirring, ultrasonic homogenization, and membrane emulsification). The oxidation rates and induction periods were almost constant, regardless of the emulsification method, except for membrane emulsification, by which the induction period was prolonged when a cellulose acetate membrane was used.
Involvement of dendritic cell response to resistance of stomach carcinogenesis caused by N-methyl-N'-nitro-N-nitrosoguanidine in rats. (1998)

The involvement of immune response in the resistance of chemically induced stomach cancer was studied in a resistant rat strain (Buffalo) and a sensitive rat strain (ACI). Groups of 10 male Buffalo and ACI rats, 6 weeks of age, were given drinking water with or without N-methyl-N'-nitro-N-nitrosoguanidine (MNNG; 100 mg/l) for 14 days. Total RNA was isolated from the stomach pyloric mucosa from five rats, and cDNA was prepared with reverse transcriptase. Tissue sections of the stomach pyloric mucosa from five rats were stained with antibodies recognizing molecules expressed by various immune cells. Reverse transcription-PCR (RT-PCR), competitive RT-PCR, and Northern blot demonstrated that the expression of MHC class II group genes [MHC class II, MHC class II-associated invariant chain (Ii), CD4 and IgM (B cell marker)], MHC class I group genes (MHC class I and CD8), B7-1 (costimulator on dendritic cells), and CD28 (receptor to B7 on T cells) in the pyloric mucosa was elevated by MNNG in both rat strains but was elevated to a 4-7-fold greater extent in Buffalo rats than in ACI rats. These genes were scarcely expressed in control rats. Histochemical antibody staining after MNNG exposure showed a greater number of cells stained with monoclonal antibody to Ii, OX-62 (dendritic cell marker), and ED-1 (dendritic cell and macrophage common marker) in the interstitial tissue of the pyloric mucosa of Buffalo rats compared with ACI rats. Cell proliferation, as measured by 5-bromo-2-deoxyuridine (BrdUrd)-labeling indices, revealed the presence of BrdUrd-labeled cells only among epithelial cells in the proliferative zone; cells in the interstitial tissue were not labeled with BrdUrd. The results suggest the involvement of dendritic cell response in the resistance to the MNNG induction of stomach carcinogenesis in rats.
Communication-Aware Motion Planning in Mobile Networks (2011)

In this technical note, we propose a communication-aware motion planning framework to increase the probability that a robot maintains its connectivity to a fixed station, while accomplishing a sensing task, in realistic communication environments. We use a probabilistic multi-scale model for channel characterization. Using this model, we propose a probabilistic framework for assessing the spatial variations of a wireless channel, based on a small number of measurements. We then show how our channel learning framework can be utilized for devising communication-aware motion planning strategies. We first present communication-aware objective functions that can plan the trajectory of the robot in order to improve its online channel assessment in an environment. We then propose a communication-aware target tracking approach for the case where a fixed station utilizes a robot (or a number of them) to keep track of the position of a moving target. In this approach, probabilistic channel assessment metrics are combined with sensing goals, when controlling the motion, in order to increase the amount of information that the fixed station receives about the target. Finally, we show the performance of our framework, using both real and simulated channel measurements. Overall, our results indicate that networked robotic operations can benefit considerably from our probabilistic channel assessment and its integration with sensing/motion planning.
Photoinduced phase modulation in PMMA lightguides doped with an azo dye (1990)

Polymer lightguides ofPMMA, doped with azo dyes are investigated with respect to their opto-optical or all optical properties. The TRANS-CIS photoisomerisation of the azo dyes leads to reasonable polarization dependent optically induced refractive index changes. These are studied in planar lightguides and in leaky guides. With light at the absorption edge all optical properties are studied leading to a possible application as bistable device.
Guest Editorial - A personal journey in Acute Medicine (2022)

This article describes my personal journey through Acute Medicine from the late 1980's and incorporates the development of Acute Medical Units (AMU's), co-establishing the Society for Acute Medicine (SAM), as well as involvement in the development of training curricula, research and audit. I am deeply indebted to a great number of professional colleagues over the last three decades, who have been pivotal to the development of the Acute Medicine specialism, and many of whom in turn became presidents of SAM.
ALU-array based reconfigurable accelerator for energy efficient executions (2009)

This paper introduces an energy efficient acceleration technique for embedded microprocessors. By means of supporting an ALU-array based coarse-grain reconfigurable functional unit, well customized special instructions are identified and executed for each application program. Since the reconfigurable functional unit can execute several dependent instructions (a sequence of instructions), simultaneously, the performance of the base microprocessor can dramatically be improved. In addition, this kind of direct execution is very energy efficient because it reduces activation counts of hardware components such as instruction cache, branch predictor, register-file accesses, and so on.
Mining Distance-Based Outlier Taking Into Account Class Label (2012)

Outlier mining attracted increasing interests in recent years, but previous proposed approaches have been focused on finding suspicious objects that deviate significantly from the rest of the whole dataset irrespective of their class labels. In many cases, object that deviates from the rest objects in the same class are also worth noticed. In this paper, a new outlier definition which takes into account the class labels is introduced. A measure for identifying the degree of being such outlier, called Class Labeled Outlier Factor (CLOF) is proposed. The outlier mining algorithm, named CLOD (Class Labeled Outlier Detection) is presented and implemented. Experiments on both real dataset and synthetic dataset are conducted to evaluate its efficiency and effectiveness. Experimental result show the proposed approach is practical and achieves a high detection rate with a low false alarm rate.
CYP2C19 and Nongenetic Factors Predict Poor Responsiveness to Clopidogrel Loading dose after Coronary Stent Implantation (2008)

Prediction of responsiveness after clopidogrel loading dose may substantially be improved by adding CYP2C19*2 genotype to nongenetic risk factors.
Organized Activation During Atrial Fibrillation in Man (1998)

An organized activation during atrial fibrillation with a predominant craniocaudal direction on the trabeculated right atrium is frequently present and influences the appearance of "coarse" or "fine" atrial fibrillation as well as F wave polarity on the surface ECG.
Synthetic polymers in artificial hearts: a progress report (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic polymers in artificial hearts: a progress reportMichael Szycher and Victor L. PoirierCite this: Ind. Eng. Chem. Prod. Res. Dev. 1983, 22, 4, 588–593Publication Date (Print):December 1, 1983Publication History Published online1 May 2002Published inissue 1 December 1983https://pubs.acs.org/doi/10.1021/i300012a014https://doi.org/10.1021/i300012a014research-articleACS PublicationsRequest reuse permissionsArticle Views358Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Na <sup>+</sup> Channel Mutation That Causes Both Brugada and Long-QT Syndrome Phenotypes (2002)

We demonstrate that the 1795insD mutation can cause both LQT and Brugada syndromes through interaction with the heterogeneous myocardium in a rate-dependent manner. The results highlight the complexity and multiplicity of genotype-phenotype relationships, and the usefulness of computational approaches in establishing a mechanistic link between genetic defects and functional abnormalities.
Towards detection of orthogonal planes in monocular images of indoor environments (2008)

In this paper, we describe the components of a novel algorithm for the extraction of dominant orthogonal planar structures from monocular images taken in indoor environments. The basic building block of our approach is the use of vanishing points and vanishing lines imposed by the frequently observed dominance of three mutually orthogonal vanishing directions in man-made world. Vanishing points are found by an improved approach, taking no assumptions on known internal or external camera parameters. The problem of detecting planar patches is attacked using a probabilistic framework, searching for the maximum a posteriori probability (MAP) in a Markov Random Field (MRF). For this, we propose a novel formulation fusing geometric information obtained from vanishing points and features, such as rectangles and partial rectangles, together with a color-homogeneity criteria imposed by an image over-segmentation. The method was evaluated on a set of images exhibiting largely varying characteristics concerning image quality and scene complexity. Experiments show that the method, despite the variations, works in a stable manner and that its performance compares favorably to the state-of-the-art.
The role of bicarbonate in GABAA receptor‐mediated IPSPs of rat neocortical neurones. (1993)

1. The ionic mechanism underlying the fast, GABAA receptor-mediated inhibitory postsynaptic potential (IPSPA) was examined in rat neocortical neurones using intracellular recording techniques. Synaptic responses were evoked by orthodromic stimulation applied to the subcortical white matter or to the pial surface. All experiments were carried out at a constant extracellular Cl- concentration. 2. The resting membrane potential was -76.2 +/- 1.0 mV (mean +/- S.E.M., n = 32) and in most cells IPSPA was depolarizing. The reversal potential of IPSPA (EIPSP-A) was -70.2 +/- 0.9 mV (n = 32) and that of a more slowly developing hyperpolarizing response (IPSPB) was -91.4 +/- 1.3 mV (n = 28). 3. An examination of the temporal relationships between excitatory postsynaptic potentials (EPSPs) and IPSPAs in different cells suggested that, despite partial overlap of these responses, EPSPs had little influence on the measured values of EIPSP-A. 4. Application of 20 mM trimethylamine (TriMA), a membrane-permeant weak base which is expected to produce a rise in pHi (and hence in intracellular HCO3-), induced a reversible positive shift in EIPSP-A of up to +9.0 mV (mean + 4.2 mV) at an extracellular pH (pHo) of 7.4. In some experiments, the shift in reversal potential was associated with a change in the polarity of IPSPA from hyperpolarizing to depolarizing. 5. Application of 20 mM lactate (a membrane-permeant weak acid which is expected to produce a fall in pHi and hence in intracellular HCO3-) at pHo 7.0 produced a hyperpolarizing shift in EIPS-A of up to -7.5 mV (mean -5.6 mV). In some experiments, exposure to lactate changed the polarity of IPSPA from depolarizing to hyperpolarizing. 6. Changes in pHo from 7.4 to 7.0 reduced the effect of TriMA and augmented that of lactate on EIPSP-A, as could be expected on the basis of the pHo-dependent change in the fraction of membrane permeable non-charged weak base or acid. 7. Under control conditions, a change in pHo from 7.4 to 7.0 produced a slight positive shift (< +2 mV) in EIPSP-A. In the presence of TriMA, a similar change in pHo gave rise to a negative shift (-1.8 to -2.7 mV). 8. The results obtained indicate that HCO3- ions contribute significantly to the IPSPA, thereby making EIPSP-A more positive than the Cl- equilibrium potential.(ABSTRACT TRUNCATED AT 400 WORDS)
HMB in DRAM-less NVMe SSDs: Their usage and effects on performance (2020)

Solid-state drives (SSDs) that do not have internal dynamic random-access memory (DRAM) are being widely spread for client SSD and embedded SSD markets in recent years because they are cheap and consume less power. Obviously, their performance is lower than conventional SSDs because they cannot exploit advantages of DRAM in the controller. However, this problem can be alleviated by using host memory buffer (HMB) feature of Non-Volatile Memory Express (NVMe), which allows SSDs to utilize the DRAM of host. In this paper, we show that commercial DRAM-less SSDs clearly exhibit worse I/O performance than SSDs with internal DRAM, but this can be improved by using the HMB feature. We also present methods that reveal how the host memory buffer is used in commercial DRAM-less SSDs to improve I/O performance. Through extensive experiments, we conclude that DRAM-less SSDs evaluated in this study mainly exploit the host memory buffer as an address mapping table cache rather than a read cache or write buffer to improve I/O performance.
Bradyrhizobium japonicum Inoculation and Seed Priming for Fluid‐Drilled Soybean (1989)

Abstract Microbial inoculation coupled with seed priming has potential application in fluid‐drilled cropping systems. The feasibility of applying Bradyrhizobium japonicum during seed priming and at planting using cellulose‐based gels was evaluated with soybean, Glycine max (L.) Merr. A greenhouse study evaluated whether exposure to Strain USDA 110SK or 123SR for 24 h during seed priming increased soybean nodulation by those strains compared to a subsequently applied gel‐carried strain. Well‐nodulated soybeans resulted when inoculation occurred only during seed priming. However, whenever gel inoculation was used, soybean nodules were almost exclusively occupied by the strain applied with the gel, regardless of whether the root radicle had or had not emerged prior to inoculation at seed priming. Differences in condition of seedbeds and soils at planting, and between fluid and conventional planting systems, influenced results from two field sites in eastern Nebraska. Strain 123SR occupied 5 to 10% of nodules at a Sharpsburg‐soil (fine, montmorillonitic, mesic Typic Argiudoll) site when carried in a cellulose‐based fluid gel at planting. Inoculation during solid‐matrix seed priming had little effect on nodule occupancy and Strain 123SR was not recovered when peat was used as a carrier. In contrast, 123SR was rarely recovered, regardless of treatment, from a Kennebec soil (finesilty, mixed, mesic Cumulic Hapludoll). Fewer nodules formed on Kennebec‐ than Sharpsburg‐soil soybeans (17 vs. 31 nodules/plant). Increased grain yields were observed at the Kennebec site (2.87 vs. 2.24 Mg/ha) when fluid‐drilled soybean seed was solid‐matrix primed. Seed priming apparently aided soybean establishment under dry soil conditions. Field delivery of viable bradyrhizobia in gel was shown to be feasible for fluid‐drilled soybean. Short‐term exposure to Bradyrhizobium inocula during seed priming did not increase soybean nodulation by that strain.
Microstructured Devices for Transdermal Drug Delivery and Minimally-Invasive Patient Monitoring (2007)

Transdermal drug delivery offers certain advantages over conventional oral or parenteral administration. However, the excellent barrier function of the skin, accomplished almost entirely by the stratum corneum, restricts the number of drug substances that can be administered transdermally to those with very specific physicochemical properties. Several approaches have been used to enhance the transport of drugs through the stratum corneum. However, in many cases, only moderate success has been achieved and each approach is associated with significant problems. Microstructured devices, consisting of a plurality of microprojections attached to a support, can be used to painlessly bypass the stratum corneum barrier and thus achieve successful transdermal delivery. Moreover, microprojection devices also enable minimally-invasive sampling and monitoring of biological fluids. Much activity is currently focussed in this area. Accordingly, this article deals with the innovations pertaining to microprojection-based devices for transdermal drug delivery and minimally-invasive monitoring as disclosed in recent patent literature.
Typical MIMO propagation channels in urban macrocells at 2GHz (2007)

International audience
Host-Guest Engineering of Layered Double Hydroxides towards Efficient Oxygen Evolution Reaction: Recent Advances and Perspectives (2018)

Electrochemical water splitting has great potential in the storage of intermittent energy from the sun, wind, or other renewable sources for sustainable clean energy applications. However, the anodic oxygen evolution reaction (OER) usually determines the efficiency of practical water electrolysis due to its sluggish four-electron process. Layered double hydroxides (LDHs) have attracted increasing attention as one of the ideal and promising electrocatalysts for water oxidation due to their excellent activity, high stability in basic conditions, as well as their earth-abundant compositions. In this review, we discuss the recent progress on LDH-based OER electrocatalysts in terms of active sites, host-guest engineering, and catalytic performances. Moreover, further developments and challenges in developing promising electrocatalysts based on LDHs are discussed from the viewpoint of molecular design and engineering.
Dosimetric evaluation for exposure of patient to a <i>z</i>-gradient coil in magnetic resonance imaging (2011)

In magnetic resonance imaging, time-varied gradient magnetic fields may stimulate nerves and muscles by inducing electric fields and currents in patients, which may potentially cause health problems. In this paper, a realistic z-gradient coil was numerically designed and the exposure level in a 3D real human man model was calculated by using the impedance method. It was found that the z-gradient coil produces a magnetic flux density (B-field) with two regions of good homogeneity along the coil length, separated by a very weak B-field in the middle of the coil. The spatially averaged B-field is 281 times greater than that of the International Commission on Non-Ionizing Radiation Protection’s (ICNIRP) reference level. The 1-cm2-averaged induced current density in the central nervous system is 87 times greater than that of the ICNIRP’s basic restriction. The maximum current density in all of the body tissues is above the nerve stimulation threshold.
Cooling effects on nitric oxide production by rabbit ear and femoral arteries during cholinergic stimulation (1994)

1. Ear (cutaneous) and femoral (deep) arteries from rabbit were perfused at 37 degrees C and 24 degrees C (cooling) and the production of nitrite, as an index of nitric oxide production, was measured under basal conditions and cholinergic stimulation. 2. In both types of arteries under control conditions, the basal production of nitrite was similar at 24 degrees C and 37 degrees C. Compared with the control conditions, the basal production of nitrite was significantly lower in ear and femoral arteries without endothelium or treated with NG-nitro-L-arginine methyl ester (L-NAME, 10(-4) M) but it was similar in those treated with atropine (10(-6) M). 3. At 37 degrees C, methacholine (10(-7)-10(-5) M) increased the production of nitrite in ear and femoral arteries; this increase persisted during 30-60 min and was practically abolished by L-NAME (10(-4) M), atropine (10(-6) M), or removal of the endothelium. In ear arteries the total nitrite production to activation with methacholine was higher at 24 degrees C than at 37 degrees C due to this production persisted increased for a longer period (> 150 min), whereas in femoral arteries it was lower at 24 degrees C than at 37 degrees C. 4. It is suggested that: (a) the endothelium of rabbit ear and femoral arteries produce nitric oxide under basal conditions, which is increased by cholinergic stimulation, and (b) cooling potentiates endothelial nitric oxide production to cholinergic stimulation in cutaneous arteries, whereas it inhibits this production in deep arteries.
Metalloprotein entatic control of ligand-metal bonds quantified by ultrafast x-ray spectroscopy (2017)

The multifunctional protein cytochrome c (cyt c) plays key roles in electron transport and apoptosis, switching function by modulating bonding between a heme iron and the sulfur in a methionine residue. This Fe-S(Met) bond is too weak to persist in the absence of protein constraints. We ruptured the bond in ferrous cyt c using an optical laser pulse and monitored the bond reformation within the protein active site using ultrafast x-ray pulses from an x-ray free-electron laser, determining that the Fe-S(Met) bond enthalpy is ~4 kcal/mol stronger than in the absence of protein constraints. The 4 kcal/mol is comparable with calculations of stabilization effects in other systems, demonstrating how biological systems use an entatic state for modest yet accessible energetics to modulate chemical function.
CVD Al<sub>2</sub>O<sub>3</sub> Films on III-V Binary Semiconductors (1980)

Chemical vapor deposited Al 2 O 3 films grown on various kinds of III-V compound semiconductor substrate were examined and compared with each other. The ion-beam etching technique was employed as a detection method of non-uniformity lurking inside the film. Dependence of the film quality on the substrate crystal was clearly found : Uniform film was obtained on GaSb. Fairly high density of non-uniformity was found in the films on InP, InSb, InAs and GaAs.