gebhart/patrepeval huggingface dataset:
Synthesis of psicofuranine cyclic 4',6'-monophosphate (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of psicofuranine cyclic 4',6'-monophosphatePriscilla A. Sturm, Elmer J. Reist, and Jon P. MillerCite this: J. Org. Chem. 1982, 47, 22, 4367–4370Publication Date (Print):October 1, 1982Publication History Published online1 May 2002Published inissue 1 October 1982https://pubs.acs.org/doi/10.1021/jo00143a048https://doi.org/10.1021/jo00143a048research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Isocyanate acting as a carbonyl precursor: pyridyl group-assisted formation of 4H-pyrido[1,2-a]pyrimidin-4-ones from ketimines and isocyanates (2005)

By the reactions of ketimines bearing a pyridyl or a picolyl group on a nitrogen atom of the imine moiety with tosylisocyanate, 4H-pyrido[1,2-a]pyrimidin-4-one derivatives could be obtained in quantitative yields. In these reactions, tosylisocyanate acts as a carbonyl precursor. The pyridyl or picolyl group is a key functional group because it is not only the constituent structure of the 4H-pyrido[1,2-a]pyrimidin-4-one framework but also the promoter of the formation of a ketene intermediate.
Gateway (October 2013) (2013)

Articles: How Will The Government Shut Down Affect College Students? by Marissa Russo;\nAvoiding the Freshman Fifteen: Fitness and Health by Maria Almonte;\nFM Holds Transfer Fair by Marissa Russo;\n79 Million Young Adults Have HPV Sexual Disease by Corina Boehme;\nClub Fair Goes Up In Smoke by Anthony Auspelmyer;\n2013 Halloween Movie Reviews by Jordan Lincourt;\nStudents Elected To Fulmont College Association by Shaunice Harris;\nTACTConference by Lisa Gandia;\nTV, Music & Entertainment by Erica Redwood;\nPure Heronie Review by Ruben;\nMental Health Counseling Now Offered by Corine Walker;\nIntramural Sports Delayed by Carlos Rivera;
Surveillance and conformity in competitive youth swimming (2010)

Underpinned by a Foucauldian analysis of sporting practices, this paper identifies the disciplinary mechanism of surveillance at work in competitive youth swimming. It highlights the ways in which swimmers and their coaches are subject to and apply this mechanism to produce embodied conformity to normative behaviour and obedient, docile bodies. The data were drawn from a wider ethnographic study of 17 competitive squads and 13 coaches at three competitive swimming clubs in England. Data from participant observations of squad training sessions and semi-structured interviews with swimming coaches indicate that the pressure of being under constant surveillance leads athletes to submit to intensive training protocols and coaches to perform according to norms dictated by discourses of child safety. For athletes, submitting to these normalised training protocols increases risk of short and long-term injury and psychological harm. Meanwhile, working in a climate where discourses of child safety position every act of child�adult touch as suspicious leaves coaches feeling resentful, angry and constrained and denies them and their swimmers one of the most fulfilling, rewarding relationships available: that between a coach and an athlete.
Torque disturbance rejection in high accuracy tracking systems (1990)

The possibility of rejecting torque disturbances that degrade the pointing and tracking accuracy of electromechanical pedestals and general two-axis systems used for target acquisition and robotics is discussed. Torque rejection achieved through disturbance estimation and compensation results in a vast improvement in pointing accuracy. For the class of disturbances considered, comparisons of a classical loop configuration of a tracker, modeled as a two-mass system, with the state-space solution indicate that at least an order-of-magnitude improvement in tracking error can be achieved.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Turbo-Like Codes for Transmission of Correlated Sources over Noisy Channels (2007)

In this article we focus on distributed coding of correlated sources that are transmitted through either separated noisy channels (one per source) or over a multiple access channel (MAC). For simplicity, we consider only two sources, but the proposed approach can be easily extended to the case of more sources. The two sources are encoded independently of each other (i.e., for a given source neither the realization from the other source nor the correlation model are available at the encoder site) and transmitted through the channel. Then, the correlation between the sources is exploited at a common receiver, aiming at the reconstruction of the two sources. Although this problem has many practical applications e.g., in the case of sensor networks (where correlated data has to be communicated between the different nodes) and video/image applications, we will focus in the key ideas without discussing specific applications. For simplicity, we will assume simple correlation models and binary sources.
Three dimensional image synthesis: theory and application (2003)

Inverse Synthetic Aperture Radar (ISAR) provides full-range detection and classification of sea-based and air-based targets through two-dimensional range-Doppler imaging. The Naval Postgraduate School (NPS) has developed a custom integrated circuit that can simulate false ISAR images in order to fool enemy ISAR platforms. To validate specific hardware choices within this design, this thesis explores the effect on image quality of an overflow occurring within the final 16-bit summation adder of this circuit, Three solutions to the problem of overflows are presented and analyzed. The logical extension of ISAR development, that of three-dimensional target imaging, is next presented through the discussion of 3D monopulse radar, 3D interferometer ISAR, and a 3D, three-receiver ISAR. The relative strengths of each approach are compared, along with both MATLAB and Extensible 3D (X3D) Graphics software models created for one specific 3D ISAR implementation. Through the superposition of 2D ISAR images it is shown how 3D ISAR images may be created. Moreover, emphasis is placed on using this knowledge to both enhance current 2D ISAR techniques and to modify the false-target chip design to handle 3D ISAR return signals. The thesis concludes with a study of Non-Uniform Rational 13-Splines, through which the X3D software model was created.
Green IT More Than a Three Percent Solution? (2009)

IT infrastructure is definitely going green. From significant new regulations for IT equipment disposal to stringent energy-efficiency specifications for PCs and monitors to national standards for data center power savings, Green IT is an "in" topic. But many problems are unsolved. Information and communications technology (ICT) infrastructure accounts for roughly 3 percent of global electricity usage and the same percentage of greenhouse gasses (GHGs), but it seems to have a far greater role in the green debate than that. Many of the solutions being introduced for reducing the carbon footprint via more efficient energy use worldwide are heavily dependent on IT - for example, improvements in the power grid, "energy-smart" buildings and cities, and so on. Here, the author examines green issues and solutions in IT infrastructure and give a brief history behind green computing.
Review: Progress in liquid crystal displays by new developments in functional polymers (2001)

Abstract Functional polymers have become essential in the functioning and performance of many products for information and communication technologies. Special polymers have been constructed with an accurate control over their morphology to a size down to the wavelength of light. These polymers improve liquid crystal displays on eye-catching properties like brightness and viewing angle. The improved energy efficiency is crucial for the mobile communication equipment in today’s information society.
Resistance Minimum of Magnesium: Electrical Resistivity below 1°K (1957)

Measurements of the electrical resistivity of the two magnesium specimens described by Spohr and Webber in the preceding paper have been extended to temperatures below 1\ifmmode^\circ\else\textdegree\fi{}K. At the lowest temperature at which data were obtained (0.22\ifmmode^\circ\else\textdegree\fi{}K), the electrical resistivities of both specimens were continuing to increase. The ratio $\frac{{\ensuremath{\rho}}_{0.22\ifmmode^\circ\else\textdegree\fi{}\mathrm{K}}}{{\ensuremath{\rho}}_{4.22\ifmmode^\circ\else\textdegree\fi{}\mathrm{K}}}$ was found to be 1.05 for the purer specimen and 1.24 for the less pure (manganese alloy) specimen.
Management of Acute Stroke (2003)

Stroke ranks as the third leading cause of death and the most common cause of permanent disability in adults. Timely recognition and treatment is imperative to reduce stroke-related morbidity and mortality. Patients with acute ischemic stroke should be evaluated for administration of intravenous tissue plasminogen activator (t-PA); those who do not qualify for t-PA should receive aspirin therapy in the absence of a contraindication. In all stroke patients, intravenous hydration with normal saline should be administered, hypoxia should be corrected with supplemental oxygen, and hyperglycemia and fever should be treated aggressively. Blood pressure management should be individualized on the basis of stroke pathophysiology and specific treatment plan (e.g., planned thrombolysis) following published guidelines. Evaluation of stroke etiology should be undertaken, and the results should be used to guide secondary stroke prevention efforts.
Elevated VEGF concentrations in ascites and serum predict adverse prognosis in ovarian cancer (2013)

Elevated VEGF-C concentrations in serum and ascites can be seen as the novel, widely available independent predictors of shorter overall survival in ovarian cancer.
Lampreys of the Iberian Peninsula: distribution, population status and conservation (2011)

The 3 lamprey species, sea lamprey Petromyzon marinus L., European river lamprey Lampetra fluviatilis L. and European brook lamprey L. planeri Bloch, that inhabit the Iberian Peninsula are of conservation concern. They are considered either Vulnerable, Critically Endangered, and even Extinct in different regions of this area mainly due to habitat loss and population fragmentation. Although several other factors contribute to the decline of lamprey populations in Iberian rivers, obstacles to migration (dams and weirs) are probably the most widespread and significant, causing an estimated 80% loss of accessible habitat in most river basins. We analysed historical records from all main Iberian rivers before the construction of impassable dams became widespread, and found that lampreys were consistently present in the upper reaches. The unblocking of the lower stretches of major river basins and the restoration of former spawning sites and larval habitats should be considered as priority measures for the conservation of these species. Identification of Special Areas of Conservation to be included in the Natura 2000 European network can also be very relevant for lamprey conservation.
4-AcNH-TEMPO-CATALYZED OXIDATION OF ALDOSES TO ALDARIC ACIDS USING CHLORINE OR BROMINE AS TERMINAL OXIDANTS (2002)

The 4-AcNH-TEMPO-catalyzed oxidation of d-glucose to d-glucaric acid using elemental chlorine or bromine as the terminal oxidant is reported. The pH and temperature of the reactions were closely controlled to be between 0–5°C and pH 11.5, respectively. Spectroscopically (1H NMR) determined yields of glucarate were greater than 90%; yields of crystalline monopotassium d-glucarate (or disodium d-glucarate), isolated and purified by precipitation, were between 70 and 85%. Oxidations of mannose to mannaric acid and galactose to mucic acid were also demonstrated.
GaAs-Al<i>x</i>Ga1-<i>x</i>As injection lasers with distributed Bragg reflectors (1975)

Room-temperature operation of an optically integrated double heterostructure (DH) GaAs-AlxGa1-xAs injection laser with a distributed Bragg reflector (DBR), with threshold current densities of 5 kA/cm2 is reported. The DBR was in the form of a third-order grating which was ion milled on a passive single heterostructure (SH) waveguide section with the latter taper coupled to the active DH section. The observed half-power spectral bandwidth was ≲1 Å. A highly collimated beam output with a half-power divergence angle of ≲0.3° was also achieved by coupling the scattered light from the oil-immersed grating at the Bragg angle with a prism.
Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery (2016)

The combined properties of neuroprotection, neurogenesis, and memory enhancement in a single drug are more likely to be effective for the treatment of age-associated neurodegenerative disorders than any individual activity alone.
Recovery of <i>Streptococcus iniae</i> from Diseased Fish Previously Vaccinated with a <i>Streptococcus</i> Vaccine (2001)

Streptococcus iniae was recovered from diseased rainbow trout (Oncorhynchus mykiss, Walbaum) previously vaccinated against streptococcosis. PCR and serological methods indicate the presence of a new serotype in the diseased fish.
Structured treatment interruptions as a potential alternative therapeutic regimen for HIV-infected patients: a review of recent clinical data and future prospects (2002)

Highly active antiretroviral therapy (HAART) allows for substantial control of HIV replication in vivo, and has caused a significant decline in morbidity and mortality rates among patients. However, eradication of the virus from the body is not possible. Therefore, HAART necessarily becomes a life-long treatment and this is associated with several problems: (i) the high cost of therapy; (ii) increased frequency of drug-related side effects; (iii) viral resistance; and (iv) poor patient adherence to the treatment. Based on these considerations, among other alternative strategies, structured treatment interruptions (STI) have been proposed with the potential object-ive of inducing immune-mediated control of HIV replication in HIV-infected patients. The available clinical data indicate that STI might increase HIV-specific, cell-mediated immune responses in patients treated during primary HIV infection; however, it does not seem to have the same effect in patients treated during chronic infection. Nevertheless, in chronically infected patients STI might limit drug-related side effects by decreasing exposure to drugs, without influencing the efficacy of the therapy. In addition, recent data suggest a possible role for immune-modulations such as hydroxyurea and therapeutic vaccines as adjuvant therapies for limiting viral rebound in these patients. Preliminary indications suggest that there is reduced hope for STI as a salvage therapy. Finally, it is important to stress that no controlled, randomized studies of STI have been held in humans, and it is not possible to evaluate fully the clinical impact of such a strategy. Therefore, clinicians and patients should avoid using STI outside the setting of controlled clinical trials.
Simultaneous Parameter Calibration, Localization, and Mapping (2012)

Abstract The calibration parameters of a mobile robot play a substantial role in navigation tasks. Often these parameters are subject to variations that depend either on changes in the environment or on the load of the robot. In this paper, we propose an approach to simultaneously estimate a map of the environment, the position of the on-board sensors of the robot, and its kinematic parameters. Our method requires no prior knowledge about the environment and relies only on a rough initial guess of the parameters of the platform. The proposed approach estimates the parameters online and it is able to adapt to non-stationary changes of the configuration. We tested our approach in simulated environments and on a wide range of real-world data using different types of robotic platforms.
Antigen-pulsed dendritic cells expressing macrophage-derived chemokine elicit Th2 responses and promote specific humoral immunity (2001)

Macrophage-derived chemokine (MDC) is a potent chemoattractant for antigen-specific T lymphocytes. We hypothesized that Adenovirus- (Ad-) transduced dendritic cells (DCs) overexpressing MDC would enhance the T cell-mediated humoral immune response specific for antigens presented by the DC. We challenged two strains of mice with lethal Pseudomonas aeruginosa infection 3 weeks after immunization with AdMDC-modified DCs pulsed with heat-killed P. aeruginosa. MDC-expressing DCs specifically attracted T lymphocytes and preserved typical DC surface phenotypes without growth factors in vitro. Mice immunized with AdMDC/Pseudomonas/DCs developed high levels of serum anti-Pseudomonas Ab's and were protected from a lethal respiratory challenge with Pseudomonas. The in vivo protective immunity required CD4(+) T cells, B cells, and IL-4, but not CD8(+) T cells and IL-12. AdMDC/DCs pulsed with Pseudomonas yielded significant but not absolute cross-protection against different strains of P. aeruginosa. Pseudomonas-pulsed AdMDC/DCs protected mice from Pseudomonas but not Escherichia coli and vice versa; this microbe-specific protection correlated with microbe-specific induction of CD4(+) T cell proliferation and IL-4 secretion. Based on these observations, AdMDC-modified DCs pulsed with a killed bacteria may be a useful approach to vaccination against infectious disorders.
IBM Burlington's Logistics Management System (1990)

IBM's logistics management system (LMS) is a real-time imbedded transaction-based integrated decision and knowledge-based expert support system which serves as a dispatcher, monitoring and controlling the manufacturing flow of IBM's semiconductor facility near Burlington, Vermont. Burlington produces various logic and memory micro electronic chips and modules that are used throughout the IBM product line. LMS helps improve manufacturing performance and is critical to running major areas of the manufacturing facility. It was developed by the advanced industrial engineering department.
Severe asthma: from characteristics to phenotypes to endotypes (2012)

Asthma, and severe asthma, in particular, is increasingly recognized as a heterogeneous disease. While traditional views of asthma have centered around a childhood onset disease with an allergic component, several large scale network studies are now confirming that severe asthma can present in multiple different ways, only 30-50% of which meet traditional childhood onset allergic criteria. To understand the different groups better, initial studies have attempted to define phenotypes of severe asthma. A phenotype is defined as the integration of different characteristics that are the product of the interaction of the patient's genes with the environment. Both clinical and statistical approaches have identified at least 3-5 phenotypes of severe asthma. However, these phenotypes, in isolation, do not identify the immunopathology that makes these clinical phenotypes distinct or identifies a target population for a specific approach to therapy. As biological characteristics are identified, phenotypes should continue to evolve towards asthma endotypes. The identification of these endotypes, either by matching biology, genetics and therapeutic responses to therapy with clinically or statistically defined phenotypes or through unbiased genetic and genomic approaches, remains limited. Moving forward, this integration of genetics, biology and clinical characteristics should substantially enhance our ability to effectively treat complex heterogeneous diseases, such as severe asthma.
Effects of high temperature on key enzymes activity of nitrogen metabolism in flag leaf and protein content in grain after flowering of early-indica rice (2011)

Estigate the effects of high temperature on key enzymes(GS and GOGAT)activity of nitrogen metabolism in flag leaf and protein content after flowering in two different early indica rice,high temperature(31.5 ℃)and optimal temperature(23.5 ℃)are treated to two different type early indica rice(Xiangzaoxian 24 and Zhuliangyou 611).The results showed that the GS and GOGAT activity were highest on 10 d under high temperature treatment and were slowly decreased under optimal temperature treatment.Activity of two kinds of key enzyme in Xiangzaoxian 24 were both higher than that in Zhuliangyou 611.Compared to optimal temperature treatment in Xiangzaoxian 24 under high temperature,the protein content was 4.75 mg higher on 22 d and 1.88mg higher for Zhuliangyou 611.These results suggest that high temperature can help to improve two early indica rice(especial the Xiangzaoxian 24)the GS and GOGAT activity in flag leaf and grain protein content.
Aromatic Fluorine Compounds. IV. 1,2,3,5-Tetrafluorobenzene<sup>1</sup> (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAromatic Fluorine Compounds. IV. 1,2,3,5-Tetrafluorobenzene1G. C. Finger, F. H. Reed, and R. E. OesterlingCite this: J. Am. Chem. Soc. 1951, 73, 1, 152–153Publication Date (Print):January 1, 1951Publication History Published online1 May 2002Published inissue 1 January 1951https://pubs.acs.org/doi/10.1021/ja01145a054https://doi.org/10.1021/ja01145a054research-articleACS PublicationsRequest reuse permissionsArticle Views165Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts