gebhart/patrepeval huggingface dataset:
Observation of Resistive and Magnetic Anomalies at 90-180 K in Artificially Layered Ca<sub>1-x</sub>Sr<sub>x</sub>CuO<sub>2</sub> Thin Films Grown by Laser Molecular Beam Epitaxy (1992)

Thin films of Ca 1- x Sr x CuO 2 have been grown by alternate deposition of Ca 1- x Sr x and CuO 2 atomic layers in a low pressure NO 2 ambient. X-ray diffraction and its intensity analysis have confirmed the formation of an infinite layer structure of Ca 1- x Sr x CuO 2 with x =0.2-1.0. The lattice constant c and electrical conductivity increase systematically with increasing Sr/Ca ratio. Clear diamagnetic signals at 90 K and 120 K have been observed in SrCuO 2 and Ca 0.2 Sr 0.8 CuO 2 films, respectively. In the Ca 0.2 Sr 0.8 CuO 2 films, the onset of a small diamagnetic signal and a resistivity drop are also observed around 180 K.
A Tight Combinatorial Algorithm for Submodular Maximization Subject to a Matroid Constraint (2012)

We present an optimal, combinatorial 1-1/e approximation algorithm for monotone sub modular optimization over a matroid constraint. Compared to the continuous greedy algorithm (Calinescu, Chekuri, Pal and Vondrak, 2008), our algorithm is extremely simple and requires no rounding. It consists of the greedy algorithm followed by local search. Both phases are run not on the actual objective function, but on a related non-oblivious potential function, which is also monotone sub modular. In our previous work on maximum coverage (Filmus and Ward, 2011), the potential function gives more weight to elements covered multiple times. We generalize this approach from coverage functions to arbitrary monotone sub modular functions. When the objective function is a coverage function, both definitions of the potential function coincide. The parameters used to define the potential function are closely related to Pade approximants of exp(x) evaluated at x = 1. We use this connection to determine the approximation ratio of the algorithm.
Cellular Concrete Block Revetment (1965)

An experimental revetment of specially designed cellular concrete revetment blocks was constructed on an eroding streambank in western New York. Over a period of 8 yr the 4-in. thick revetment has given satisfactory performance under severe conditions. In contrast, an adjacent revetment of quarried stone riprap has been less effective in withstanding the erosive forces. Square holes run entirely through the depth of the block. These holes serve several purposes: They mechanically hold gravel and crushed stone in place, thus reducing the erosive forces at the surface of the bank; allow planting of vegatative materials on the bank; and reduce the block weight making handling easier. When the blocks are mass-produced and where quarried stone is available locally, the costs of the types of revetments would be approximately the same.
A firewall for Internet of Things (2017)

With the advent of the Internet of Things (IoT), privacy and security of sensitive data has become a major concern. In general, sensors which are the enablers for IoT, send the sensed data to a cloud database over the internet. The communication to the cloud database may be compromised by an adversary, or the database maybe accessed by a curious database administrator, thereby raising security concerns. To solve this issue, we demonstrate a solution to safeguard IoT devices in a home network scenario from potential attacks. A firewall is set up using a Raspberry Pi as a gateway which secures their communication with the cloud database. Furthermore, we plan to build a location-aware (physical location in the home network scenario) heuristics and a signature based traffic detection dashboard running on the Raspberry Pi, in order to control the IoT devices and log their network behavior.
Human Immunodeficiency Virus Type 1 (HIV-1) Antigen Secretion by Latently Infected Resting CD4 <sup>+</sup> T Lymphocytes from HIV-1-Infected Individuals (2004)

In resting CD4(+) T lymphocytes harboring human immunodeficiency virus type 1 (HIV-1), replication-competent virus persists in patients responding to highly active antiretroviral therapy (HAART). This small latent reservoir represents between 10(3) and 10(7) cells per patient. However, the efficiency of HIV-1 DNA-positive resting CD4(+) T cells in converting to HIV-1-antigen-secreting cells (HIV-1-Ag-SCs) after in vitro CD4(+)-T-cell polyclonal stimulation has not been satisfactorily evaluated. By using an HIV-1-antigen enzyme-linked immunospot assay, 8 HIV-1-Ag-SCs per 10(6) CD4(+) resting T cells were quantified in 25 patients with a plasma viral load of <20 copies/ml, whereas 379 were enumerated in 10 viremic patients. In parallel, 369 and 1,238 copies of HIV-1 DNA per 10(6) CD4(+) T cells were enumerated in the two groups of patients, respectively. Only a minority of latently HIV-1 DNA-infected CD4(+) T cells could be stimulated in vitro to become HIV-1-Ag-SCs, particularly in aviremic patients. The difference between the number of HIV-1 immunospots in viremic versus aviremic patients could be explained by HIV-1 unintegrated viral DNA that gave additional HIV-1-Ag-SCs after in vitro CD4(+)-T-cell polyclonal stimulation. The ELISPOT approach to targeting the HIV-1-Ag-SCs could be a useful method for identifying latently HIV-1-infected CD4(+) T cells carrying replication-competent HIV-1 in patients responding to HAART.
Expression of Interleukin-26 is upregulated in inflammatory bowel disease (2017)

These results suggest that IL-26 plays a role in the pathophysiology of IBD through induction of inflammatory mediators.
Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health? (2010)

SCFAs show anti-inflammatory effects and seem to have the potency to prevent infiltration of immune cells from the bloodstream in, for example, the adipose tissue. In addition, their ability to inhibit the proliferation and activation of T cells and to prevent adhesion of antigen-presenting cells could be important as it recently has been shown that obesity-associated inflammation might be antigen-dependent. More studies with concentrations in micromolar range are needed to approach more physiological concentrations.
Primary Structure and Biochemical Properties of an M <sub>2</sub> Muscarinic Receptor (1987)

A partial amino acid sequence obtained for porcine atrial muscarinic acetylcholine receptor was used to isolate complementary DNA clones containing the complete receptor coding region. The deduced 466-amino acid polypeptide exhibits extensive structural and sequence homology with other receptors coupled to guanine nucleotide binding (G) proteins (for example, the beta-adrenergic receptor and rhodopsins); this similarity predicts a structure of seven membrane-spanning regions distinguished by the disposition of a large cytoplasmic domain. Stable transfection of the Chinese hamster ovary cell line with the atrial receptor complementary DNA leads to the binding of muscarinic antagonists in these cells with affinities characteristic of the M2 receptor subtype. The atrial muscarinic receptor is encoded by a unique gene consisting of a single coding exon and multiple, alternatively spliced 5' noncoding regions. The atrial receptor is distinct from the cerebral muscarinic receptor gene product, sharing only 38% overall amino acid homology and possessing a completely nonhomologous large cytoplasmic domain, suggesting a role for the latter region in differential effector coupling.
P. Ovidi Nasonis Fastorum Libri VI. Recensuit Carolus Landi: editionem paravit alteram L. Castiglioni. (Corpus Scr. Latin. Paravianum.) Pp. lxiv + 241. Turin: Paravia, 1950. Paper, <i>L.</i> 1,200. (1952)

P. Ovidi Nasonis Fastorum Libri VI. Recensuit Carolus Landi: editionem paravit alteram L. Castiglioni. (Corpus Scr. Latin. Paravianum.) Pp. lxiv + 241. Turin: Paravia, 1950. Paper, L. 1,200. - Volume 2 Issue 3-4
Thiazolylaminomannosides As Potent Antiadhesives of Type 1 Piliated Escherichia coli Isolated from Crohn’s Disease Patients (2013)

Adherent-invasive Escherichia coli (AIEC) have previously been shown to induce gut inflammation in patients with Crohn's disease (CD). We developed a set of mannosides to prevent AIEC attachment to the gut by blocking the FimH bacterial adhesin. The crystal structure of the FimH lectin domain in complex with a lead thiazolylaminomannoside highlighted the preferential position for pharmacomodulations. A small library of analogues showing nanomolar affinity for FimH was then developed. Notably, AIEC attachment to intestinal cells was efficiently prevented by the most active compound and at around 10000-fold and 100-fold lower concentrations than mannose and the potent FimH inhibitor heptylmannoside, respectively. An ex vivo assay performed on the colonic tissue of a transgenic mouse model of CD confirmed this antiadhesive potential. Given the key role of AIEC in the chronic intestinal inflammation of CD patients, these results suggest a potential antiadhesive treatment with the FimH inhibitors developed.
The integral image method for fisheye images (2013)

Because of strong radial distortion, fisheye images have to be rectified before use in most computer vision algorithms. We investigate three ways to rectify fisheye images: the rectangular local perspective projection, local perspective projection bounded by longitude and latitude lines, and cylindrical projection. The traditional integral image method doesn't work for local projections, because they produce patches with curved edges. We find the integral over any local projection patch by traversing the patch edges, rather than using just the corner values. This is slower than the conventional method, but still fast enough for real time applications. We can compute integrals for 5000 patches in 10 ms on a fisheye image of 640 × 480 pixels. Computing local projections themselves is slow (120 ms for 5000 patches), while the cylindrical projection needs only 15 ms for the whole image.
Design Techniques for Wideband Single-Bit Continuous-Time $\Delta\Sigma$ Modulators With FIR Feedback DACs (2012)

We give design considerations for single-bit continuous-time Delta-Sigma modulators (CTDSMs) with FIR feedback DACs. These modulators have the low jitter sensitivity and high linearity properties characteristic of a multibit modulator, while using a simple one-bit quantizer, thereby combining the advantages of single-bit and multibit operation. We propose a method to compensate the loop for the delay introduced by the FIR-DAC. The efficacy of our architectural and circuit techniques is borne out by measurement results from a modulator that achieves about 71-dB SNDR in a 36-MHz bandwidth while consuming only 15 mW from a 1.2-V supply. Implemented in a 90-nm CMOS process and sampling at 3.6 GS/s, the CTDSM has a figure of merit (FoM) of 72.7 fJ/lvl, while occupying 0.12 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Perturbation Analysis of Nonlinear Propagation in a Strongly Dispersive Optical Communication System (2013)

We discuss an analytical model that predicts the impact of the Kerr nonlinearity in optical communication systems when the signal spectrum is wide and the accumulated dispersion during propagation is large. A detailed derivation of this model is given for a generalized system by means of a perturbation analysis of the Manakov equation with attenuation, gain, and third order dispersion included. As in the case with previous studies, three simplifying assumptions are necessary. These are that (i) the nonlinearity is weak, (ii) the input signal is of a given specific form, and (iii) the signal-noise interaction can be neglected. Under these assumptions, the result is found exactly. We also discuss the accuracy of the analytical result and show that third order dispersion has a small impact in practice.
Carbohydrate chains from human bronchial mucus glycoproteins: a wide spectrum of oligosaccharide structures (1984)

Conference Article| August 01 1984 Carbohydrate chains from human bronchial mucus glycoproteins: a wide spectrum of oligosaccharide structures G. LAMBLIN; G. LAMBLIN *Unité INSERM no. 16, 59045 Lille Cédex, France Search for other works by this author on: This Site PubMed Google Scholar M. LHERMITTE; M. LHERMITTE *Unité INSERM no. 16, 59045 Lille Cédex, France Search for other works by this author on: This Site PubMed Google Scholar A. KLEIN; A. KLEIN *Unité INSERM no. 16, 59045 Lille Cédex, France Search for other works by this author on: This Site PubMed Google Scholar P. ROUSSEL; P. ROUSSEL Search for other works by this author on: This Site PubMed Google Scholar H. VAN HALBEEK; H. VAN HALBEEK †Department of Bio-Organic Chemistry, University of Utrecht, NL-3522 AD Utrecht, The Netherlands Search for other works by this author on: This Site PubMed Google Scholar J. F. G. VLIEGENTHART J. F. G. VLIEGENTHART †Department of Bio-Organic Chemistry, University of Utrecht, NL-3522 AD Utrecht, The Netherlands Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1984) 12 (4): 599–600. https://doi.org/10.1042/bst0120599 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation G. LAMBLIN, M. LHERMITTE, A. KLEIN, P. ROUSSEL, H. VAN HALBEEK, J. F. G. VLIEGENTHART; Carbohydrate chains from human bronchial mucus glycoproteins: a wide spectrum of oligosaccharide structures. Biochem Soc Trans 1 August 1984; 12 (4): 599–600. doi: https://doi.org/10.1042/bst0120599 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1984 Biochemical Society1984 Article PDF first page preview Close Modal You do not currently have access to this content.
The Californian Species of Malthodes (1919)

The presence of several species of Malthodes among the things which Dr. Blaisdell has asked me to study in connection with his forthcoming paper on the Coleoptera of Humboldt County, California, offers the opportunity of reviewing the Californian species of this genus in the Doctor’s and my own collections, a very large proportion of which are as yet undescribed.
HDM2 protein overexpression, but not gene amplification, is related to tumorigenesis of cutaneous melanoma. (2001)

We investigated the role of alterations of HDM2, the human homologue of murine mdm2, in the tumorigenesis and progression of cutaneous melanoma. A well-characterized cohort of 172 cases representing different points in the spectrum of melanocyte transformation (16 dysplastic nevi, 11 melanomas in situ, 107 invasive primaries, and 38 metastatic lesions), as well as 11 human melanoma cell lines were examined by immunohistochemistry and Western blotting for HDM2 protein expression, and by either Southern blotting (SB) or fluorescence in situ hybridization for HDM2 gene amplification. HDM2 overexpression, defined as >20% tumor cells showing nuclear immunoreactivity, was observed in 1 of 16 (6%) dysplastic nevi, 3 of 11 (27%) melanomas in situ, and 81 of 145 (56%) invasive primary and metastatic melanomas. Comparable frequencies of HDM2 overexpression were observed among invasive primary cases with differing tumor thicknesses as well as among the metastatic cases: 21 of 40 (53%) at < or =1.5 mm; 31 of 50 (62%) at 1.6-3.9 mm; 10 of 17 (58%) at >4 mm; and 19 of 38 (50%) metastases. HDM2 amplification was observed in 1 of 88 (1%) primary cases using fluorescence in situ hybridization, and in 0 of 12 (0%) metastatic cases that overexpressed HDM2 using SB. Melanoma cell lines expressed HDM2 protein, but there was no evidence of amplification by SB. Our data suggest that HDM2 protein overexpression is common in invasive and metastatic melanoma. Observing HDM2 overexpression in noninvasive melanoma suggests that expression of this oncogene may play an early role in melanocyte transformation. HDM2 amplification occurs infrequently, and other mechanisms that up-regulate HDM2 expression are under investigation.
DC‐20 GHz 5‐BIT CMOS digital step attenuator with low insertion loss and phase error (2013)

Abstract This article presents a 5‐bit broadband digital step attenuator with low insertion loss and phase error using a standard 0.13 μm CMOS process for the phased array antenna.The maximum attenuation of 31 dB with the LSB of 1 dB is achieved at DC‐20 GHz. The measured insertion loss of the reference state is <11 dB and the input and output return losses are <−10 dB at DC‐20 GHz. The root mean square (RMS) phase and amplitude errors are <2.5° and <0.7 dB, respectively. The current consumption is near zero with 1.2 V supply. The chip size is 1.04 × 0.48 mm 2 including pads. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:762–764, 2013; View this article online at wileyonlinelibrary.com. DOI: 10.1002/mop.27448
Anomaly Detection via Feature-Aided Tracking and Hidden Markov Models (2008)

The problem of detecting an anomaly (or abnormal event) is such that the distribution of observations is different before and after an unknown onset time, and the objective is to detect the change by statistically matching the observed pattern with that predicted by a model. In the context of asymmetric threats, the detection of an abnormal situation refers to the discovery of suspicious activities of a hostile nation or group out of noisy, scattered, and partial intelligence data. The problem becomes complex in a low signal-to-noise ratio environment, such as asymmetric threats, because the ldquosignalrdquo observations are far fewer than ldquonoiserdquo observations. Furthermore, the signal observations are ldquohiddenrdquo in the noise. In this paper, we illustrate the capabilities of hidden Markov models (HMMs), combined with feature-aided tracking, for the detection of asymmetric threats. A transaction-based probabilistic model is proposed to combine HMMs and feature-aided tracking. A procedure analogous to Page's test is used for the quickest detection of abnormal events. The simulation results show that our method is able to detect the modeled pattern of an asymmetric threat with a high performance as compared to a maximum likelihood-based data mining technique. Performance analysis shows that the detection of HMMs improves with increase in the complexity of HMMs (i.e., the number of states in an HMM).
Family Romance as National Allegory in Yeats's Cathleen ni Houlihan and The Dreaming of the Bones (1986)

La constitution psychologique de l'allegorie nationale irlandaise dans ces deux pieces de Y. Lecture psychanalytique
Electroanalysis and Biosensors in Clinical Chemistry (2000)

Abstract Electroanalysis involves the measurement or determination of a chemical or biochemical species, using a wide range of electrochemical methods. The species being measured can either bring about a direct electrochemical response that can be detected and measured, or can be induced to bring about such a response, resulting in a process that can be detected electrochemically. In both cases an interface is required between the chemical or biochemical species being measured, and the electrochemical system performing the measurement. This interface is referred to as an “electrode”. It is the transfer of electrons or ions between the electrode and the environment being sampled which is of concern in electroanalysis. The application of electrochemistry in clinical analysis is concerned with the measurement of chemical and biochemical species present in biological fluids (primarily blood but also urine and other body fluids and tissues). It is applied in several areas of critical care where its rapidity, sensitivity, precision, and accuracy at biologically relevant concentrations make it an ideal choice over other, typically slower, biochemical techniques. Indeed, it is the speed of electrochemical analysis that principally differentiates it from other methods. It is not universally applicable to clinical chemistry, however, and has only been applied in situations where such analyses are relevant. This has principally been in the analysis of blood gases and pH and blood electrolytes. Electrochemical methods are, however, gradually being extended to the analysis of small biochemical components such as sugars, amino acids and other metabolites, with the advent of enzyme‐based “biosensors”. There is also little doubt that the application of electrochemistry in clinical analysis will be further exploited by the use of such biosensor devices based on other forms of biorecognition, such as antibodies, cell ligands, membranes, tissues and whole cells. These biosensor devices are also amenable to other forms of detection such as acoustic wave and optical measurements. Together, these techniques offer a wide range of advantages over traditional analytical methodologies, and will undoubtedly have a rapidly increasing impact on many types of clinical analysis. This article focuses on the use of electrochemical techniques and electrochemical biosensors and their application in clinical chemistry.
Enantiomer separation using BSA as chiral stationary phase in affinity OTEC and OTLC (1998)

The protein bovine serum albumin (BSA) was chemically bound to the inner surface of fused silica capillaries by a gentle coupling procedure in order to form a stable chiral stationary phase. Enantiomer separation of a number of DNP-amino acids and 3-hydroxy-1,4-benzodiazepines was possible in affinity open tubular electrokinetic chromatography (affinity OTEC) and open tubular liquid chromatography (OTLC) in one instrumental setup. This approach combines the advantages of high efficiency and small consumption of solvent and chiral selector with the possibility of UV detection without limitations of protein absorption. © 1998 John Wiley & Sons, Inc. J Micro Sep 10: 287–291, 1998
The Effect of Flow Rate on Drug Delivery from the Pulvinal, a High-Resistance Dry Powder Inhaler (1998)

Dry powder inhalers vary widely in their resistance to flow. When the resistance is high, airway resistance can be neglected and inspiration rates will be determined primarily by the device. Provided that the patient can generate adequate flow rates to aerosolize the dose, variability of emitted dose and fine particle dose should be reduced. For in vitro simulation, these concepts are explored using a Pulvinal device. In conditions likely to be encountered in patient use, the emitted dose showed little dependence (80-102 micrograms) as the flow rate increased from 28 to 63 L/min. The fine particle dose was more sensitive, increasing by a factor of 1.6 from 22 to 35 micrograms. These variations are less than those observed with the Turbohaler, a device of intermediate resistance and very much lower than those observed with the Rotahaler, a low-resistance device.
Presbyopia: a new potential pharmacological treatment. (2012)

Presbyopia occurs after 40 years of age in humans with a progressive loss of accommodation. Accommodation depends on the contraction of the ciliary muscle and iris, lens changes and convergence. The parasympathetic system regulates the degree of ciliary muscle and iris contraction necessary to modify the shape and position of the lens and its stimulation is effective through the activation of muscarinic receptors that are present in both structures. The hypothesis proposed here suggests the correction of accommodation in emmetropic presbyopic patients using a pharmacological treatment that includes a cholinergic agent combined with non-steroidal anti-inflammatory drugs (NSAIDs). This drug combination can restore near vision without affecting distance vision. It is important to note that the pharmaceutical form used was devoid of any inflammatory or other collateral effects.