gebhart/patrepeval huggingface dataset:
A Novel Antivortex Turbine Film-Cooling Hole Concept (2008)

A novel turbine film-cooling hole shape has been conceived and designed at NASA Glenn Research Center. This “antivortex” design is unique in that it requires only easily machinable round holes, unlike shaped film-cooling holes and other advanced concepts. The hole design is intended to counteract the detrimental vorticity associated with standard circular cross-section film-cooling holes. This vorticity typically entrains hot freestream gas and is associated with jet separation from the turbine blade surface. The antivortex film-cooling hole concept has been modeled computationally for a single row of 30 deg angled holes on a flat surface using the 3D Navier–Stokes solver GLENN-HT. A blowing ratio of 1.0 and density ratios of 1.05 and 2.0 are studied. Both film effectiveness and heat transfer coefficient values are computed and compared to standard round hole cases for the same blowing rates. A net heat flux reduction is also determined using both the film effectiveness and heat transfer coefficient values to ascertain the overall effectiveness of the concept. An improvement in film effectiveness of about 0.2 and in net heat flux reduction of about 0.2 is demonstrated for the antivortex concept compared to the standard round hole for both blowing ratios. Detailed flow visualization shows that as expected, the design counteracts the detrimental vorticity of the round hole flow, allowing it to remain attached to the surface.
ENUM-based Softswitch Requirement (2007)

This document describes operational requirement and several
considerations for ENUM-based softswitch, which can route a call
between 2 Korean VoIP carriers during the ENUM pre-commercial trial
hosted by National Internet Development Agency of Korea(NIDA) in 2006.
This experience can be one of interim solution to maintain stability
of on-going commercial softswitch system while initial stage of ENUM
service that does not have sufficient data.
Performance evaluatio of MPEG-4 visual error resilient tools over a mobile channel (2003)

MPEG-4 is the most recent standard for audiovisual representation published by International Organization for Standardization, targeted for future interactive multimedia video communications calling for content-based functionalities, universal access in error prone environments and high coding efficiency. Besides the provisions for content-based functionalities, the MPEG-4 video coding standard will assist the efficient storage and transmission of very low bit rate video in error prone environments. This makes MPEG-4 a good candidate for video coding standard for Terrestrial Trunked Radio Standard (TETRA) video transmission. This paper presents the overall performance of a communication system used to transmit MPEG-4 encoded video over TETRA channels. The video quality that can be achieved at different channel conditions employing different combination of MPEG-4 built-in error resilient tools are presented in this paper.
Pain patterns and descriptions in patients with radicular pain: Does the pain necessarily follow a specific dermatome? (2009)

In most cases nerve root pain should not be expected to follow along a specific dermatome, and a dermatomal distribution of pain is not a useful historical factor in the diagnosis of radicular pain. The possible exception to this is the S1 nerve root, in which the pain does commonly follow the S1 dermatome.
OCV Hysteresis in Li-Ion Batteries including Two-Phase Transition Materials (2011)

The relation between batteries' state of charge (SOC) and open-circuit voltage (OCV) is a specific feature of electrochemical energy storage devices. Especially NiMH batteries are well known to exhibit OCV hysteresis, and also several kinds of lithium-ion batteries show OCV hysteresis, which can be critical for reliable state estimation issues. Electrode potential hysteresis is known to result from thermodynamical entropic effects, mechanical stress, and microscopic distortions within the active electrode materials which perform a two-phase transition during lithium insertion/extraction. Hence, some Li-ion cells including two-phase transition active materials show pronounced hysteresis referring to their open-circuit voltage. This work points out how macroscopic effects, that is, diffusion limitations, superimpose the latte- mentioned microscopic mechanisms and lead to a shrinkage of OCV hysteresis, if cells are loaded with high current rates. To validate the mentioned interaction, Li-ion cells' state of charge is adjusted to 50% with various current rates, beginning from the fully charged and the discharged state, respectively. As a pronounced difference remains between the OCV after charge and discharge adjustment, obviously the hysteresis vanishes as the target SOC is adjusted with very high current rate.
Yeast Frataxin Sequentially Chaperones and Stores Iron by Coupling Protein Assembly with Iron Oxidation (2003)

We have investigated the mechanism of frataxin, a conserved mitochondrial protein involved in iron metabolism and neurodegenerative disease. Previous studies revealed that the yeast frataxin homologue (mYfh1p) is activated by Fe(II) in the presence of O2 and assembles stepwise into a 48-subunit multimer (alpha48) that sequesters >2000 atoms of iron in 2-4-nm cores structurally similar to ferritin iron cores. Here we show that mYfh1p assembly is driven by two sequential iron oxidation reactions: A ferroxidase reaction catalyzed by mYfh1p induces the first assembly step (alpha --> alpha3), followed by a slower autoxidation reaction that promotes the assembly of higher order oligomers yielding alpha48. Depending on the ionic environment, stepwise assembly is associated with accumulation of 50-75 Fe(II)/subunit. Initially, this Fe(II) is loosely bound to mYfh1p and can be readily mobilized by chelators or made available to the mitochondrial enzyme ferrochelatase to synthesize heme. Transfer of mYfh1p-bound Fe(II) to ferrochelatase occurs in the presence of citrate, a physiologic ferrous iron chelator, suggesting that the transfer involves an intermolecular interaction. If mYfh1p-bound Fe(II) is not transferred to a ligand, iron oxidation, and mineralization proceed to completion, Fe(III) becomes progressively less accessible, and a stable iron-protein complex is formed. Iron oxidation-driven stepwise assembly is a novel mechanism by which yeast frataxin can function as an iron chaperone or an iron store.
Unsupported small metal particles: preparation, reactivity, and characterization (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUnsupported small metal particles: preparation, reactivity, and characterizationStephen C. Davis and Kenneth J. KlabundeCite this: Chem. Rev. 1982, 82, 2, 153–208Publication Date (Print):April 1, 1982Publication History Published online1 May 2002Published inissue 1 April 1982https://pubs.acs.org/doi/10.1021/cr00048a002https://doi.org/10.1021/cr00048a002research-articleACS PublicationsRequest reuse permissionsArticle Views926Altmetric-Citations213LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Differential Effect of Anti-B7-1 and Anti-M150 Antibodies in Restricting the Delivery of Costimulatory Signals from B Cells and Macrophages (1998)

B7-1 and M150 are potent costimulatory molecules expressed on B cells and macrophages. We have examined the capacity of Abs against B7-1 and M150 in differentially inhibiting the costimulatory signals delivered by macrophages and B cells to OVA-specific CD4+ T cells. The anti-B7-1 Ab significantly blocked the proliferation of Th cells, MLR, T cell help to B cells, and secretion of IFN-gamma when B cells were used to provide costimulation, but not when macrophages were used. In contrast, anti-M150 Ab significantly decreased the proliferation of Th cells, MLR, and production of IFN-gamma, when macrophages were utilized to provide costimulatory signals, but not when B cells were used as APC. However, when macrophages activated with IFN-gamma were used as a source of costimulation, like anti-M150 Ab, Ab to B7-1 also down-regulated the activation of Th cells. The significance of this finding is that M150 is a potent first costimulatory signal for initiating proliferation and secretion of IFN-gamma and providing cognate help for B cells by Th cells when the macrophage is used as an accessory cell. M150-induced IFN-gamma production induces the expression of B7-1 on the surface of macrophages, which then delivers a second cosignal for Th cells. B7-1 works efficiently when B cell provides cosignal. Both of the molecules promote Th1 activity, as evidenced by the inhibition of the secretion of IFN-gamma but not IL-4 by Th cells with anti-M150 and B7-1 Abs.
Overcoming the J-shaped distribution of product reviews (2009)

Introduction While product review systems that collect and disseminate opinions about products from recent buyers (Table 1) are valuable forms of word-of-mouth communication, evidence suggests that they are overwhelmingly positive. Kadet notes that most products receive almost five stars. Chevalier and Mayzlin also show that book reviews on Amazon and Barnes & Noble are overwhelmingly positive. Is this because all products are simply outstanding? However, a graphical representation of product reviews reveals a J-shaped distribution (Figure 1) with mostly 5-star ratings, some 1-star ratings, and hardly any ratings in between. What explains this J-shaped distribution? If products are indeed outstanding, why do we also see many 1-star ratings? Why aren't there any product ratings in between? Is it because there are no "average" products? Or, is it because there are biases in product review systems? If so, how can we overcome them? The J-shaped distribution also creates some fundamental statistical problems. Conventional wisdom assumes that the average of the product ratings is a sufficient proxy of product quality and product sales. Many studies used the average of product ratings to predict sales. However, these studies showed inconsistent results: some found product reviews to influence product sales, while others did not. The average is statistically meaningful only when it is based on a unimodal distribution, or when it is based on a symmetric bimodal distribution. However, since product review systems have an asymmetric bimodal (J-shaped) distribution, the average is a poor proxy of product quality. This report aims to first demonstrate the existence of a J-shaped distribution, second to identify the sources of bias that cause the J-shaped distribution, third to propose ways to overcome these biases, and finally to show that overcoming these biases helps product review systems better predict future product sales. We tested the distribution of product ratings for three product categories (books, DVDs, videos) with data from Amazon collected between February--July 2005: 78%, 73%, and 72% of the product ratings for books, DVDs, and videos are greater or equal to four stars (Figure 1), confirming our proposition that product reviews are overwhelmingly positive. Figure 1 (left graph) shows a J-shaped distribution of all products. This contradicts the law of "large numbers" that would imply a normal distribution. Figure 1 (middle graph) shows the distribution of three randomly-selected products in each category with over 2,000 reviews. The results show that these reviews still have a J-shaped distribution, implying that the J-shaped distribution is not due to a "small number" problem. Figure 1 (right graph) shows that even products with a median average review (around 3-stars) follow the same pattern.
Resonant Cavity Time-Division-Multiplexed Fiber Bragg Grating Sensor Interrogator (2004)

The first resonant-cavity time-division-multiplexed (TDM) fiber Bragg grating sensor interrogation system is reported. This novel design uses a pulsed semiconductor optical amplifier in a cyclic manner to function as the optical source, amplifier, and modulator. Compatible with a range of standard wavelength detection techniques, this optically gated TDM system allows interrogation of low reflectivity "commodity" sensors spaced just 2 m apart, using a single active component. Results demonstrate an exceptional optical signal-to-noise ratio of 36 dB, a peak signal power of over +7 dBm, and no measurable crosstalk between sensors. Temperature tuning shows that the system is fully stable with a highly linear response.
Beta‐Adrenoceptor Antagonist‐Induced Psoriasiform Eruption (1988)

A number of beta-adrenoceptor blocking drugs have been reported to induce a papulosquamous eruption which resembles psoriasis. We report distinctive clinical, histopathologic, immunocytochemical, and electron microscopic features in beta-blocker-induced psoriasiform eruptions that differentiate this syndrome from psoriasis. Preliminary data suggest that biopsy specimens from eruptions caused by beta 1-selective adrenoceptor blocking agents (metoprolol and atenolol) were characterized by excessive degranulation of the neutrophils in the dermis, while the nonselective beta blockers (propranolol, nadolol, and sotalol) were marked by excessive release of proteolytic enzymes from macrophages, which are thought to possess beta 2-adrenergic receptors. Surprisingly, excessive release of enzymes by lymphocytes were noted in both the beta 1-selective and in the nonselective induced syndromes. It is believed that excessive lysosomal enzyme release by neutrophils, lymphocytes, and macrophages is responsible for the presence of basal keratinocyte herniations, which have previously been shown to correlate with hyperproliferation and psoriasiform changes, as well as with the presence of excessive proteolytic enzymes in the skin. It is postulated that the beta-blocker-induced syndrome may result from enhanced proliferation, motility, and activity of lymphocytes, neutrophils, and cells of the macrophage-Langerhans cell series, stemming from depressed intracellular cyclic adenosine monophosphate levels caused by the beta blockade.
Nuclear Localization of Enzymatically Active Green Fluorescent Protein-CTP:Phosphocholine Cytidylyltransferase α Fusion Protein Is Independent of Cell Cycle Conditions and Cell Types (2000)

To address the recent controversy about the subcellular localization of CTP:phosphocholine cytidylyltransferase alpha (CTalpha), this study was designed to visualize green fluorescent protein (GFP). CTalpha fusion proteins directly and continuously under different conditions of cell cycling and in various cell lines. The GFP. CTalpha fusion proteins were enzymatically active and capable of rescuing mutant cells with a temperature-sensitive CT. The expressed GFP.CTalpha fusion protein was localized to the nucleus in all cell lines and required the N-terminal nuclear targeting sequence. Serum depletion/replenishment did not cause shuttling of CTalpha between the nucleus and cytoplasm. Moreover, the subcellular localization of CTalpha was examined continuously through all stages of the cell cycle in synchronized cells. No shuttling of CTalpha between the nucleus and cytoplasm was observed at any stage of the cell cycle. Stimulation of cells with oleate had no effect on the localization of CTalpha. The GFP.CTalpha lacking the nuclear targeting sequence stayed exclusively in the cytoplasm. Regardless of their localization, the GFP.CTalpha fusion proteins were equally active for phosphatidylcholine synthesis and mutant rescue. We conclude that the nuclear localization of CTalpha is a biological event independent of cell cycle in most mammalian cells and is unrelated to activation of phosphatidylcholine synthesis.
Efficient U-Prove Implementation for Anonymous Credentials on Smart Cards (2012)

Summary. In this paper we discuss an efficient implementation of anonymous credentials on smart cards. In general, privacy-preserving protocols are computationally intensive and require the use of advanced cryptography. Implementing such protocols for smart cards involves a trade-off between the requirements of the protocol and the capabilities of the smart card. In this context we concentrate on the implementation of Microsoft’s U-Prove technology on the MULTOS smart card platform. Our implementation aims at making the smart card independent of any other resources, either computational or storage. In contrast, Microsoft suggests an alternative approach based on device-protected tokens which only uses the smart card as a security add-on. Given our very good performance results we argue that our approach should be considered in favour of Microsoft’s one. Furthermore we provide a brief comparison between Java Card and MULTOS which illustrates our choice to implement this technology on the latter more flexible and low-level platform rather than the former. Key words: anonymous credentials, smart cards, U-Prove, MULTOS, Java Card 1
Prevention of regimen-related toxicities after bone marrow transplantation by pentoxifylline: a prospective, randomized trial (1993)

Elevated levels of tumor necrosis factor alpha (TNF-alpha) have been reported to correlate with the development of transplant-related complications after bone marrow transplantation (BMT). In a recent phase I-II trial, oral administration of pentoxifylline (PTX), a xanthine derivative capable of downregulating TNF-alpha production in vitro, was reported to reduce morbidity and mortality in patients undergoing BMT. We conducted a prospective randomized trial of PTX therapy among 140 patients undergoing either allogeneic (n = 51) or autologous BMT (n = 89). Patients were randomized to receive (n = 70) or not receive (n = 70) oral PTX, 1,600 mg/d in four divided doses from day -8 until day + 100 post-BMT. The incidence of mucositis requiring morphine sulfate (MSO4) was similar in both groups (42.9%), with the mean number of days with MSO4 being 7.8 (SD = 3.4) in the PTX group versus 8.2 (SD = 3.4) in the control group (NS). The incidence of renal insufficiency was not affected by PTX administration (15.7% in the PTX group v 21.4% in the control group [NS]) and the highest serum creatinine value during the first 100 days post-BMT was 119 mumol/L (SD = 82.4) in the PTX group versus 103.9 mumol/L (SD = 57) in the control group (NS). The incidence of grade > or = 2 graft-versus-host disease was similar in each group (11/25 [44%] in the PTX group v 12/26 [46%] in the control group). No significant difference was observed in hematologic toxicity, transfusion requirements, duration of fever, and hepatic toxicity between the treatment groups. In conclusion, our study failed to show a prophylactic effect of PTX in transplant-related toxicities after BMT. On the basis of these findings, we cannot recommend that PTX be part of early mortality and morbidity prevention programs after BMT.
Self-Supervised Sparse-to-Dense: Self-Supervised Depth Completion from LiDAR and Monocular Camera (2019)

Depth completion, the technique of estimating a dense depth image from sparse depth measurements, has a variety of applications in robotics and autonomous driving. However, depth completion faces 3 main challenges: the irregularly spaced pattern in the sparse depth input, the difficulty in handling multiple sensor modalities (when color images are available), as well as the lack of dense, pixel-level ground truth depth labels for training. In this work, we address all these challenges. Specifically, we develop a deep regression model to learn a direct mapping from sparse depth (and color images) input to dense depth prediction. We also propose a self-supervised training framework that requires only sequences of color and sparse depth images, without the need for dense depth labels. Our experiments demonstrate that the self-supervised framework outperforms a number of existing solutions trained with semi-dense annotations. Furthermore, when trained with semi-dense annotations, our network attains state-of-the-art accuracy and is the winning approach on the KITTI depth completion benchmark at the time of submission.
Genetic transformation of crop plants: risks and opportunities for the rural poor (2001)

The world population is increasing at an alarming rate and is expected to increase from 6.5 billion at present to 7.5 billion by 2025. Most of this population lives in the rural areas in the developing countries where poverty, food insecurity and nutritional deficiencies are the major
 problems. Low crop productivity, limited use of inputs such as fertilizers and pesticides and
 losses due to biotic and abiotic stress factors are a major constraint to increase production and
 productivity of crops. With the advent of genetic engineering, it has become possible to clone and
 insert genes into the crop plants to confer resistance to insect pests and improve the nutritional
 quality. Genetically transformed crops with Bacillus thuringiensis and herbicide resistance genes
 have been deployed for cultivation in USA, Canada, China and Australia. However, very little has
 been done to use this technology for improving crop production in the harsh environments of the
 tropics, where the need for increasing food production is most urgent. However, there is a need to
 follow the biosafety regulations and a better presentation of the results to the general public for a
 rational deployment of the genetically transformed crops for improving the livelihoods of the rural poor.
LQ-Nets: Learned Quantization for Highly Accurate and Compact Deep Neural Networks (2018)

Although weight and activation quantization is an effective approach for Deep Neural Network (DNN) compression and has a lot of potentials to increase inference speed leveraging bit-operations, there is still a noticeable gap in terms of prediction accuracy between the quantized model and the full-precision model. To address this gap, we propose to jointly train a quantized, bit-operation-compatible DNN and its associated quantizers, as opposed to using fixed, handcrafted quantization schemes such as uniform or logarithmic quantization. Our method for learning the quantizers applies to both network weights and activations with arbitrary-bit precision, and our quantizers are easy to train. The comprehensive experiments on CIFAR-10 and ImageNet datasets show that our method works consistently well for various network structures such as AlexNet, VGG-Net, GoogLeNet, ResNet, and DenseNet, surpassing previous quantization methods in terms of accuracy by an appreciable margin. Code available at https://github.com/Microsoft/LQ-Nets