gebhart/patrepeval huggingface dataset:
Improving the virtualization of rich applications by combining VNC and streaming protocols at the hypervisor layer (2015)

Summary Virtual desktop infrastructure (VDI) solutions seek to provide a satisfactory user experience at the client side when accessing remote desktop applications, even from mobile devices with limited capabilities. This paper presents a new approach, improving on previous work by the authors, in which a combination of Virtual Network Computing (VNC) and streaming protocols allowed efficient remote web access to virtualized applications within a cloud architecture. The new approach simplifies virtual machine templates, from which virtual machine instances are deployed, by centralizing software modules, greatly simplifying their management. Our new contribution consists of an integrated solution with specific WebM video encoding modules in charge of application visual output processing, an Hypertext Transfer Protocol (HTTP) streaming server, and a VNC server. The solution can be installed in the hypervisor of the host machines instead of replicating the servers and modules throughout the guest (virtual) machines that run the virtualized applications. Consequently, their implementations are unique and independent of the operating system of the virtual machines. In short, it is not necessary to provide different implementations for different operating systems, which reduces the complexity of virtual machine templates and greatly simplies platform management. To demonstrate our solution, we have modified the Quick Emulator (QEMU)‐Kernel‐based Virtual Machine (KVM) hypervisor source code accordingly. We also present qualitative and quantitative analyses that demonstrate that the new approach is advantageous in terms of software management and quality of experience, compared with our previous work and other well‐known thin clients, contributing to the enhancement of VDI systems. Copyright © 2015 John Wiley & Sons, Ltd.
Deep Convolution Networks for Compression Artifacts Reduction (2016)

Lossy compression introduces complex compression artifacts, particularly blocking artifacts, ringing effects and blurring. Existing algorithms either focus on removing blocking artifacts and produce blurred output, or restore sharpened images that are accompanied with ringing effects. Inspired by the success of deep convolutional networks (DCN) on superresolution, we formulate a compact and efficient network for seamless attenuation of different compression artifacts. To meet the speed requirement of real-world applications, we further accelerate the proposed baseline model by layer decomposition and joint use of large-stride convolutional and deconvolutional layers. This also leads to a more general CNN framework that has a close relationship with the conventional Multi-Layer Perceptron (MLP). Finally, the modified network achieves a speed up of 7.5 times with almost no performance loss compared to the baseline model. We also demonstrate that a deeper model can be effectively trained with features learned in a shallow network. Following a similar "easy to hard" idea, we systematically investigate three practical transfer settings and show the effectiveness of transfer learning in low-level vision problems. Our method shows superior performance than the state-of-the-art methods both on benchmark datasets and a real-world use case.
Effects of ACE inhibitor and AT blocker on dystrophin-related proteins and calpain in failing heart (2004)

These results suggest that attenuation in calpain-induced degradation of DRP complex is a possible mechanism for the Tra- or Can-mediated improvement of the pathogenesis of CHF following myocardial infarction.
Electronic properties of Cu-Ti metallic glasses (1983)

The electronic properties of Cu1-xTix metallic glasses (x=0.4, 0.5 and 0.6) have been studied through measurements of the low-temperature specific heat, the magnetic susceptibility and the electrical resistivity. The electronic specific heat coefficient increases with increasing Ti content. This behaviour is consistent with the UPS results and indicates the dominant contribution of the Ti 3d states at EF. The magnetic susceptibility of the amorphous phase is temperature independent and is of the order of 10-4 EMU mol.-1. It also increases with increasing Ti content. The presence of a large orbital paramagnetism is deduced and attributed to the unfilled d states at EF. The electrical resistivity increases with decreasing temperature for all alloys studied. The Ziman theory cannot be applied for such highly resistive alloys. The low-temperature resistivity below 100K does not fit to the relation rho = rho 0-AT2 (A>0), suggesting that an extra scattering mechanism is present and supersedes the effect due to the temperature dependence of the Debye-Waller factor.
Coronary Thermodilution to Assess Flow Reserve (2001)

The present findings demonstrate the validity of the thermodilution principle to assess CFR. Because the pressure-temperature sensor was mounted in a commercially available angioplasty guidewire, this technique permits simultaneous measurements of CFR and FFR.
Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia. (1991)

The oncoprotein 18 (Op18) gene encodes a proliferation-related cytosolic phosphoprotein, which is induced in normal lymphocytes following mitogenic stimulation. Studies of the Op18 gene are of particular interest because of the proposed role of Op18 protein in signal transduction and because of its occurrence in markedly increased amounts in acute leukemia cells. We have recently reported the cloning and sequencing of two cDNA clones for Op18 (1 and 1.5 kilobases). Both clones code for the same 149-amino acid polypeptide; however, they differ in their 3'-region as a result of alternative polyadenylation. We report here the sequencing of the Op18 gene and describe its expression in leukemia. The Op18 gene, which is 6.3 kilobases in length, is comprised of five exons and four introns and exhibits features that are common to other genes involved in cellular growth and proliferation. The increase in Op18 polypeptide in leukemia is associated with increased RNA transcription without gene amplification or rearrangement. Treatment of K562 leukemia cell line with hemin that induces terminal differentiation resulted in decreased expression of Op18. Our findings suggest that the high amount of Op18 protein in acute leukemia results from increased expression of a structurally unaltered gene.
Einleitung Vorverständnis und Interesse (1992)

Am Anfang meiner Beschäftigung mit den Josephsromanen war ich erfreut und fasziniert, was hier aus einer seit Kinclertagen vertrauten und heiß geliebten Geschichte gemacht worden war. Mit der Zeit stellten sich Fragen: Wie erreicht der moderne Erzähler sein Ziel einer » Vergegenwärtigung « (XI 655)? Zugleich aber auch: Steht das schon in der Bibel? Wie steht es dort? Daraus erwuchs zunächst das Interesse, dem Verhältnis des Romans zur biblischen Vorlage genauer und systematisch nachzugehen und dabei einige der Schritte nachzuvollziehen, die den langen Weg von den biblischen Quellen über die mythologischen Interpretamente bis hin zum modernen Roman kennzeichnen.
Delayed Posttraumatic Brain Hyperthermia Worsens Outcome after Fluid Percussion Brain Injury: A Light and Electron Microscopic Study in Rats (1996)

The morphological consequences of delayed posttraumatic brain hyperthermia (39 degrees C) after fluid percussion brain injury were assessed in rats. Sprague-Dawley rats anesthetized with 4% halothane and maintained on a 70:30 mixture of nitrous oxide:oxygen and 0.5% halothane underwent moderate (1.5-2.0 atm) traumatic brain injury with the injury screw positioned parasagittally over the right parieto-occipital cortex. At 24 hours after traumatic brain injury, the rats were reanesthetized and randomized into two groups in which either a 3-hour period of brain normothermia (36.5 degrees C, n = 18) or hyperthermia (39 degrees C, n = 18) was maintained. Sham-operated controls (n = 10) underwent all surgical and temperature-monitoring procedures. After the 3-hour monitoring period, the rats were allowed to survive for 3 days for light microscopic analysis or were injected with the protein tracer horseradish peroxidase and were perfusion-fixed 15 minutes later for light and electron microscopic analysis. At 4 days after traumatic brain injury, delayed posttraumatic hyperthermia (n = 12) significantly increased mortality (47%) and contusion volume (1.7 +/- 0.69 mm3, mean +/- standard error of the mean), compared to normothermia (n = 12) (18% mortality and 0.13 +/- 0.21 mm3 contusion volume) (P < 0.01, analysis of variance). At 15 minutes after the 3-hour hyperthermic period, the area of hemorrhage and horseradish peroxidase extravasation overlying the lateral external capsule was significantly increased (2.52 +/- 0.71 mm2, mean +/- standard error of the mean, versus 0.43 +/- 0.16 mm2) (P < 0.01), compared to normothermic rats. Examination of toluidine blue-stained plastic sections demonstrated a higher frequency of abnormally swollen myelinated axons per high microscopic field with hyperthermia. For example, numbers of swollen axons within the sixth layer of the right somatosensory cortex, corpus callosum, and internal capsule were 7.3 +/- 1.3, 4.2 +/- 1.4, and 3.0 +/- 1.2 axons (mean +/- standard error of the mean) with normothermia, respectively, compared with 24.7 +/- 12.1, 33.1 +/- 4.2, and 27.3 +/- 3.1 axons with hyperthermia, respectively (P < 0.01). An ultrastructural examination of the swollen axons demonstrated a severely thinned myelin sheath containing axoplasm devoid of cytoskeletal components. These experimental results indicate that posttraumatic brain hyperthermia might increase morbidity and mortality in patients with head injury by aggravating axonal and microvascular damage.
Combining strategies for white balance (2007)

In this work we consider six methods for automatic white balance available in the literature. The idea investigated does not rely on a single method, but instead considers a consensus decision that takes into account the compendium of the responses of all the considered algorithms. Combining strategies are then proposed and tested both on synthetic and multispectral images, extracted from well known databases. The multispectral images are processed using a digital camera simulator developed by Stanford University. All the results are evaluated using the Wilcoxon Sign Test.
Physical model for the contrast sensitivity of the human eye (1992)

The contrast sensitivity of the human eye and its dependence on luminance and display size is described on the basis of internal noise in the visual system. With the addition of a global description of the optical MTF of the eye, a complete physical model is obtained for the spatial contrast sensitivity function. The results of this model are compared with measurements published by various authors.
Adaptive Nulling in Time-Varying Scenarios Through Time-Modulated Linear Arrays (2012)

Unlike classical phased arrays, a key feature of time-modulated arrays (TMAs) is the ability to easily reconfigure the radiation pattern just modifying the pulse sequence that modulates the static element excitations. TMAs have proved to be effective systems for the suppression of interferences and undesired signals impinging on the antenna aperture. Such a capability has been evaluated, up to now and to the best of authors' knowledge, only in case of static scenarios with signals coming from fixed directions of arrival. This letter is devoted to investigating TMAs as applied to adaptive nulling when both the number of signals/interferences as well as the signal directions change in time. Toward this purpose, the on-off TMA sequence is optimized with a suitable global optimization technique that requires a limited computational burden and enables real-time reconfigurations. A set of representative results is reported and discussed to assess the potentialities and the effectiveness of the TMA-based adaptive nulling.
The horizontal pipeline flow of equal density oil‐water mixtures (1961)

Abstract The horizontal flow of equal density oil‐water mixtures was investigated in a 1‐inch diameter laboratory pipeline. Oils of viscosities 6.29, 16.8 and 65.0 centipoise were used in the experiments. Flow patterns, holdup ratios and pressure gradients were investigated for a range of superficial oil velocity from 0.05 to 3.0 ft./sec. and a range of superficial water velocity from 0.1 to 3.5 ft./sec, with input oil‐water ratios ranging from 0.1 to 10.0. Similar series of flow patterns were observed for each oil and were found to be largely independent of the oil viscosity. At high oil‐water ratios oil formed the continuous phase and a water‐drops‐in‐oil regime was noted. As the oil‐water ratio was decreased the flow patterns concentric oil‐in‐water, oil‐slugs‐in‐water, oil‐bubbles‐in‐water and oil‐drops‐in‐water in which water was the continuous phase were observed. The most viscous oil did, however, exhibit anomalous behavior at low superficial water velocities and this is attributed to different interfacial properties. The pressure drops measured indicated that for a given oil flow rate the pressure gradient was reduced to a minimum by the addition of water provided that the oil was not in turbulent flow. Maximum pressure gradient reduction factors varied from 1.7 for the 6.29 centipoise viscosity oil to 10 for the 65.0 centipoise viscosity oil at input oil‐water ratios of 4.5 and 1.0 respectively.
Rio: a universal multimedia storage system based on random data allocation and block replication (1998)

We describe the design, implementation and performance analysis of the RIO (Randomized I/O) Multimedia Storage System which manages a set of parallel disks and supports real-time data retrieval with statistical delay guarantees. Previous work on multimedia storage systems has concentrated on video playback. RIO, however, is designed to support much more general workloads, such as 3D interactive virtual worlds, interactive scientific visualizations, etc., in addition to video and audio play-out. 
In RIO, data objects are divided into constant size data blocks, and data blocks are placed on randomly selected disks. This converts all logical access patterns to a uniform random physical access pattern to the parallel disks, and thus facilitates simultaneous support of multiple types of applications. To provide short term load balancing, RIO replicates an arbitrary fraction of data blocks on a different disk, also randomly selected. This data redundancy gives the disk scheduler flexibility in scheduling read requests, allowing the system to reduce the short term load imbalance, and achieve high throughput with low delay bound guarantees. 
We analyze the performance of RIO through simulations and experiments in our prototype for different systems parameters. Our results show that RIO has cost/performance competitive to that of striping techniques which is a traditional approach used in previous multimedia storage systems, with the advantage of supporting much more general workloads than striping techniques. Moreover, RIO outperforms striping techniques if some replication is used, even if replication is only partial. We discuss various schemes to support fault tolerance, and compare them in terms of reliability and real-time performance under normal operation and disk failure. We also discuss the performance of RIO under heterogeneous disk configurations and show that RIO provides a simple and effective way of dealing with heterogeneity. We also describe issues involved in extending RIO to a distributed environment, composed of a cluster of PCs. In a distributed environment, load balancing is complicated by the lack of instantaneous global knowledge of the disk queue lengths. We describe several schemes for load balancing with imperfect disk load knowledge and compare them in terms of scalability and real-time performance.
Tumor Suppressor Yin-Yang (2008)

The Wnt signal transduction pathway is a critical player in the development of animals. However, inappropriate activation of this pathway triggers tumorigenesis; for example, disruption of the adenomatous polyposis coli (APC) tumor suppressor, a negative regulator of Wnt signaling, results in colorectal carcinoma development. Although APC is well known to function in inhibiting gene expression, Takacs et al. now report that fruit fly homologs of APC have an opposing job in the activation of Wnt signaling. Separable domains in APC not only restrained inappropriate signaling when the Wnt signal was absent but also promoted signaling upon Wnt stimulation. C. M. Takacs, J. R. Baird, E. G. Hughes, S. S. Kent, H. Benchabane, R. Paik, Y. Ahmed, Dual positive and negative regulation of Wingless signaling by adenomatous polyposis coli. Science 319 , 333-336 (2008). [Abstract] [Full Text]
Expression of Rumen Microbial Fibrolytic Enzyme Genes in Probiotic <i>Lactobacillus reuteri</i> (2005)

This study was aimed at evaluating the cloning and expression of three rumen microbial fibrolytic enzyme genes in a strain of Lactobacillus reuteri and investigating the probiotic characteristics of these genetically modified lactobacilli. The Neocallimastix patriciarum xylanase gene xynCDBFV, the Fibrobacter succinogenes beta-glucanase (1,3-1,4-beta-D-glucan 4-glucanohydrolase [EC 3.2.1.73]) gene, and the Piromyces rhizinflata cellulase gene eglA were cloned in a strain of L. reuteri isolated from the gastrointestinal tract of broilers. The enzymes were expressed and secreted under the control of the Lactococcus lactis lacA promoter and its secretion signal. The L. reuteri transformed strains not only acquired the capacity to break down soluble carboxymethyl cellulose, beta-glucan, or xylan but also showed high adhesion efficiency to mucin and mucus and resistance to bile salt and acid.
CAD/CAM integrated building prefabrication based on a product data model (2006)

This paper presents an approach pursued by the Forschungszentrum Karlsruhe (Karlsruhe Research Center), Germany, to prefabricating wall elements on the basis of the IFC (Industry Foundation Classes) product data model [1]. Prefabrication of wall elements for individually planned houses will only be successful, if the information flow between planning (architect) and manufacturing (machine) can be automated. Continuous information flow requires a neutral data model. The most promising product data model for buildings is the IFC model which is designed to cover the whole lifecycle and supported by various software vendors. This paper describes information flow from the planning stage to the manufacturing process. Steps necessary to prepare the building model for prefabrication will be outlined in detail. Conversion of the geometric IFC building model into a machining feature-oriented BauXML model will be shown. In the end, an example of a simple house built with floor-toceiling AAC (Autoclaved Aerated Concrete) wall elements will be given.
Current Practice for Therapeutic Drug Monitoring of Biopharmaceuticals in Spondyloarthritis (2017)

Treatment of spondyloarthritis (SpA) has greatly improved in the biopharmaceutical era. These compounds, primarily tumor necrosis factor inhibitors, are effective, but some patients may show poor response, sometimes due to the presence of antidrug antibodies (ADAs). In some instances, clinicians may increase or taper the dose, depending on the clinical response. Besides the current clinical practice, a tailored strategy based on drug monitoring is emerging as a way to improve the use of these drugs. However, the relevance of this therapeutic drug monitoring of biopharmaceuticals for SpA is still unknown. In this literature review, we examined the most relevant articles dealing with the concentration-response relation, ADA detection, and pharmacokinetics in SpA treated with biopharmaceuticals. ADAs were associated with low or undetectable concentration of monoclonal antibodies. The relation between drug concentration and clinical response in SpA is debated, some studies showing an association and others not. Therefore, therapeutic drug monitoring of biopharmaceuticals for SpA requires a better understanding of the association among the pharmacokinetics, pharmacodynamics, and immunogenicity of these drugs.
Safe and Interactive Autonomy: Control, Learning, and Verification (2017)

The goal of my research is to enable safe and reliable integration of human-robot systems in our society by providing a unified framework for modeling and design of these systems. Today's society is rapidly advancing towards autonomous systems that interact and collaborate with humans, e.g., semiautonomous vehicles interacting with drivers and pedestrians, medical robots used in collaboration with doctors, or service robots interacting with their users in smart homes. The safety-critical nature of these systems require us to provide provably correct guarantees about their performance. In this dissertation, we develop a formalism for the design of algorithms and mathematical models that enable correct-by-construction control and verification of human-robot systems.We focus on two natural instances of this agenda. In the first part, we study interaction-aware control, where we use algorithmic HRI to be mindful of the effects of autonomous systems on humans' actions, and further leverage these effects for better safety, efficiency, coordination, and estimation. We further use active learning techniques to update and better learn human models, and study the accuracy and robustness of these models. In the second part, we address the problem of providing correctness guarantees, while taking into account the uncertainty arising from the environment or human models. Through this effort, we introduce Probabilistic Signal Temporal Logic (PrSTL), an expressive specification language that allows representing Bayesian graphical models as part of its predicates. Further, we provide a solution for synthesizing controllers that satisfy temporal logic specifications in probabilistic and reactive settings, and discuss a diagnosis and repair algorithm for systematic transfer of control to the human in unrealizable settings.While the algorithms and techniques introduced can be applied to many human-robot systems, in this dissertation, we will mainly focus on the implications of my work for semiautonomous driving.
Effect of esterase on methacrylates and methacrylate polymers in an enzyme simulator for biodurability and biocompatibility testing (1994)

Current in vitro biocompatibility methods do not evaluate the degradation of biomaterials after contact with enzymes that might be present in the oral or systemic environment. In this study, two methods of in vitro enzyme degradation and a method for the separation of the degradative products by high performance thin-layer chromatography (HPTLC) are reported. In the first method two dental adhesives, Scotchbond and Scotchbond II, and two dental composites, Heliomolar and P-50, were evaluated. These materials were incubated with four different enzymatic preparations for periods of up to 72 h. The enzymes were lipase, esterase, and liver enzyme extracts from both mouse and rat. Chloroform soluble products extracted from the aqueous phase were examined by HPTLC for decomposition products resulting from enzyme activity. The second method was similar, but analyzed the aqueous fraction directly without chloroform extraction. In this method five dental restorative materials, P-50, P-30, Scotchbond II, Silux, and Silux Plus, were incubated with a nonspecific porcine liver esterase. In addition to the polymerized biomaterials, monomers containing methacrylic acid units were also hydrolyzed with esterase and analyzed by ion chromatography to establish the sensitivity of the enzyme simulator. Each biomaterial presented thin-layer zones not present before enzymatic action. These experiments provide support that aqueous enzymatic action may facilitate the hydrolytic weakening of polymeric biomaterials.
Sugar Confectionery Manufacture (2014)

Sugar confectionery manufacture , Sugar confectionery manufacture , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی