gebhart/patrepeval huggingface dataset:
Collaborative Admission Control Scheme for Group-Based P2P Contents Sharing Systems (2012)

In this paper, we proposed a user management scheme for Peer-to-Peer (P2P) contents sharing systems. The proposed scheme assumes the existence of peer groups which provide sensitive, confidential contents to the group members, and controls the membership through the collaboration among group members. As the key technique, we use the delegation of the task of qualification to few selected group members, and a voting mechanism based on the (n, t)-threshold cryptosystem. We implemented a prototype of the proposed scheme using JXTA framework, and evaluated the performance experimentally. The experimental result indicates that although the time required for the admission control is proportional to the group size and the threshold used in the threshold cryptosystem, we can significantly reduce it by executing it in parallel. We also demonstrate the availability of the scheme by applying it to the P2P live video streaming system.
Prenatal in vivo bulbourethral gland development is not affected by prostaglandin E2 inhibition. (1995)

Investigation of bulbourethral gland (BUG) development is useful to study genitourinary (GU) tract growth and differentiation. Understanding GU tract growth and differentiation is relevant to testing the hypothesis that the initial lesion of human benign prostatic hyperplasia involves focal re-expression of inductive processes in the periurethral region of the prostatic transitional zone. Prostaglandins play a role in regulating growth and morphogenesis of different organ systems. Previous reports have proposed that prostaglandin E2 (PgE2) mediates the masculinizing effects of testosterone in the developing neonatal male GU tract. We have previously shown that androgens lower rather than raise BUG PgE2 levels. Further studies led us to conclude that PgE2 does not play a major role in postnatal BUG growth and morphogenesis in vitro. In order to investigate the possible role of PgE2 in prenatal BUG development, indomethacin (INDO, 1.0 mg/kg- day, subcutaneously) was administered to pregnant BALB/c mice on gestational days 12-18. Control pregnant mice were either untreated or injected with dimethylsulfoxide vehicle. Anogenital distances were measured within 12 hours after birth in male and female offspring on day 19. In male neonatal mice, BUGs were examined histologically and PgE2 levels were measured by radioimmunoassay in BUGs and whole genital tracts. We observed no significant morphological differences in INDO-exposed BUGs compared to controls. No significant differences in mean anogenital distances of INDO-exposed male offspring or controls were detected. Mean anogenital distances of female offspring were similar in the three respective groups. Mean BUG PgE2 levels in INDO-exposed neonates were significantly lower (P < 0.05) than in untreated neonates.(ABSTRACT TRUNCATED AT 250 WORDS)
Differential expression of three alpha-tubulin genes in Chinese hamster ovary cells. (1985)

Chinese hamster ovary cells contain a complex family of ca. 16 unique alpha-tubulin sequences and a similar multiplicity of beta sequences. To examine which members of this multigene family are expressed, we constructed cDNA libraries from two Chinese hamster ovary cell lines according to the method of H. Okayama and P. Berg (Mol. Cell. Biol. 3:280-289, 1983). Each library consisted of 5.5 X 10(5) transformants and contained a high percentage of full-length tubulin clones. Three different alpha-tubulin genes were identified by sequence analysis of the 3' noncoding regions of these tubulin clones. The relative abundance of the transcripts corresponding to the three genes was estimated by gene-specific dot blotting of 96 cDNA alpha-tubulin clones and was found to be 71, 24, and 5%. There is little homology in the 3' noncoding sequences of these genes; however, a strong interspecies homology exists in this region for two of the Chinese hamster ovary genes with the two alpha-tubulin genes previously described in other systems. The third Chinese hamster ovary gene, with an expression frequency of 24%, is unique in that its 3' noncoding region is unlike that of the other mammalian alpha-tubulin genes. In addition, limited sequence data from the coding region of this gene indicates it codes for a unique alpha-tubulin protein.
Intra-axonal Location of Herpes Simplex Virus Particles (1972)

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
The Effect of Cover Crops and Fertilization with Ammonium Nitrate on Corky Root of Lettuce (1990)

Rye planted as a winter crop slightly reduced the severity of corky root early in the growing season of a subsequent lettuce crop, but at harvest the suppressive effect was observed in only one of four lettuce crops. Lettuce yields were not affected by cover crop use. Side-dressing with ammonium nitrate increased corky root severity in most plots and reduced yield in all plots. There were no significant interactions between cover crops and nitrogen fertilization with respect to lettuce yield (...)
Magnamosis II: Magnetic Compression Anastomosis for Minimally Invasive Gastrojejunostomy and Jejunojejunostomy (2010)

Minimally invasive placement of a custom magnetic device in the stomach and jejunum allows intraluminal self-alignment and subsequent compression anastomosis over 3 to 10 days. The magnamosis is immediately patent and develops strength equal to or greater than that of hand-sewn or stapled anastomoses. Magnamosis is effective in the pig model, and may be a safe, effective, and minimally invasive alternative to current anastomotic strategies in humans.
Recent Applications of the Suzuki—Miyaura Cross‐Coupling Reaction in Organic Synthesis (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
A simple genetic algorithm for tracing the deformed midline on a single slice of brain CT using quadratic Bezier curves (2006)

Midline shift (MLS) is one of the most important quantitative features clinicians use to evaluate the severity of brain compression. It can be recognized by modeling brain deformation according to the estimated biomechanical properties of the brain structures. This paper proposes a novel method to identify the deformed midline by decomposing it into three segments: the upper and the lower straight segments representing parts of the tough meninges separating two brain hemispheres, and the central curved segment formed by a quadratic Bezier curve, representing the intervening soft brain tissue. The deformed midline is obtained by minimizing the summed square of the differences across all midline points, applying a genetic algorithm. Our algorithm was evaluated on images containing various pathologies from 81 consecutive patients treated in a single institute over one-year period. The deformed midlines were evaluated by human experts, and the values of midline shift were accurate in 95%
Kinetics of the cyclotrimerization and cocyclotrimerization of isocyanates catalyzed with alkali metals alkoxides (1982)

For the rate of cyclotrimerization v t of phenyl isocyanate ( I ) in tetrahydrofuran catalyzed with Li, Na or K tert-butoxides (A) at 30 °C, the coefficients k, a, b of the empirical relation v t = k [I] a [A] 0 b were determined. The same coefficients were also determined for the cyclotrimerization of ethyl isocyanate with lithium tert-butoxide as the catalyst. The composition of the products of cocyclotrimerization of ethyl and butyl isocyanate corresponds to ratios of the rates of trimerization of the individual isocyanates. With respect to the fast decay of initiator in acetonitrile, data reported in the literature on the rate of cyclotrimerization in this solvent are not real.
Immediate, but Not Delayed, Microsurgical Skull Reconstruction Exacerbates Brain Damage in Experimental Traumatic Brain Injury Model (2012)

Moderate to severe traumatic brain injury (TBI) often results in malformations to the skull. Aesthetic surgical maneuvers may offer normalized skull structure, but inconsistent surgical closure of the skull area accompanies TBI. We examined whether wound closure by replacement of skull flap and bone wax would allow aesthetic reconstruction of the TBI-induced skull damage without causing any detrimental effects to the cortical tissue. Adult male Sprague-Dawley rats were subjected to TBI using the controlled cortical impact (CCI) injury model. Immediately after the TBI surgery, animals were randomly assigned to skull flap replacement with or without bone wax or no bone reconstruction, then were euthanized at five days post-TBI for pathological analyses. The skull reconstruction provided normalized gross bone architecture, but 2,3,5-triphenyltetrazolium chloride and hematoxylin and eosin staining results revealed larger cortical damage in these animals compared to those that underwent no surgical maneuver at all. Brain swelling accompanied TBI, especially the severe model, that could have relieved the intracranial pressure in those animals with no skull reconstruction. In contrast, the immediate skull reconstruction produced an upregulation of the edema marker aquaporin-4 staining, which likely prevented the therapeutic benefits of brain swelling and resulted in larger cortical infarcts. Interestingly, TBI animals introduced to a delay in skull reconstruction (i.e., 2 days post-TBI) showed significantly reduced edema and infarcts compared to those exposed to immediate skull reconstruction. That immediate, but not delayed, skull reconstruction may exacerbate TBI-induced cortical tissue damage warrants a careful consideration of aesthetic repair of the skull in TBI.
Secret Sharing and Multi-user Authentication (2016)

In this era of Internet of Things (IoT), connectivity exists everywhere, among everything (including people) at all times. Therefore, security, trust, and privacy become crucial to the design and implementation of IoT devices [12]. However, it is challenging to build security into IoT devices because most of them are constrained by extremely limited resources such as the battery, memory, and computation power etc. Inspired by the concept of visual cryptography [4] that requires the least amount of computation and a recent work on pure hardware-based single-user authentication [6], we present a novel solution to the secret sharing and multi-user authentication problem. Our solution is built on the observation that non-volatile resistive memories display nice monotonic and additive properties during resistive state transitions. We demonstrate how to design a hardware dependent multi-user authentication protocol using resistive random access memory (RRAM)-based hardware and provide the necessary circuits for the application. Finally, we simulate the proposed circuit to understand the nature of the operation and practical problems that these designs encounter during operation.
Low-Voltage Electrodeposition of Fullerol Thin Films from Aqueous Solutions (2006)

A low-voltage (, three-electrode system) method for the cathodic electrodeposition of fullerol [polyhydroxylated fullerene, ] from an aqueous solution has been developed for the synthesis of thin films. Scanning electron microscopy of the electrodeposited fullerol films shows that the films are microscopically uniform; the film thickness was observed to vary linearly with the deposition charge. X-ray photoelectron spectroscopy of the peak indicates that the carbon constituents of the electrodeposited films are electronically similar to the fullerol precursor. Infrared spectroscopy (IRS) confirmed that the fullerol moiety is intact upon electrodeposition and that the films are thermally stable up to . At higher temperatures IRS data suggest there is cleavage of a ketal or hemiketal group followed by hydroxyl group cleavage. The (direct) optical bandgap obtained from UV-visible spectroscopy of the electrodeposited film was .
Characterization of cathepsin B specificity by site-directed mutagenesis. Importance of Glu245 in the S2-P2 specificity for arginine and its role in transition state stabilization. (1993)

The pH dependence of cathepsin B-catalyzed hydrolyzes is very complex. At least seven dissociable groups are involved in the binding and hydrolysis of 7-amido-4-methyl coumarin and p-nitroaniline (pNA)-based substrates containing a P1 Arg and either a Phe or Arg at the P2 position. By site-directed mutagenesis we show that a previous suggestion, that Arg202 is one of the groups which influences the pH dependence of cathepsin B-catalyzed hydrolysis of the Z-Arg-Arg-pNA substrate, is not valid. However, it was found that Glu245, which has a pKa of 5.1 in rat cathepsin B, is responsible for the S2-P2 specificity for Arg-containing substrates and controls the pH dependence of their hydrolysis. Furthermore, the data indicate that Glu245, which forms a hydrogen bond with the guanidinium group of the substrate's P2 Arg, contributes about 1.8 kcal/mol to transition state stabilization in the protonated state and about 0.6 kcal/mol in the deprotonated state. Mutation of Glu245 to Gln results in a 16-fold decrease in kcat but does not affect Km. While cathepsin B has a 7-fold preference for Phe over Arg at the P2 position of a substrate, binding of the aromatic side chain does not appear to be influenced by Glu245.
How restriction enzymes became the workhorses of molecular biology (2005)

Restriction enzymes have proved to be invaluable for the physical mapping of DNA. They offer unparalleled opportunities for diagnosing DNA sequence content and are used in fields as disparate as criminal forensics and basic research. In fact, without restriction enzymes, the biotechnology industry would certainly not have flourished as it has. The first experiments demonstrating the utility of restriction enzymes were carried out by Danna and Nathans and reported in 1971. This pioneering study set the stage for the modern practice of molecular biology in which restriction enzymes are ubiquitous tools, although they are often taken for granted.
High-speed actinic EUV mask blank inspection with dark-field imaging (2004)

We proposed an actinic (at-wavelength) EUV mask blank inspection method providing a printable phase-defect detection capability within the whole area of the mask blanks in an allowable inspection time. The inspection tool based on our method consists of optics for illuminating a mask blank with an EUV light, a mask blank stage, Schwarzschild optics for dark-field imaging, and a CCD camera. Phase-defect detection experiments were performed using a 10 Hz LPP source and with 0.2 NA imaging optics with the center obscuration NA of 0.1. Two-dimensional dark field image signal of 0.5 mmX0.5 mm area was captured by the CCD camera with 1M pixels and the phase-defects with the size down to 70 nm were successfully detected. In addition, a programmed phase defect and natural defect with 2 nm height were clearly detected. Inspection time including image capture and data processing for 0.5 mmX0.5 mm area was approximately 2 second. This is equivalent to an inspection time of 800 seconds/cm<sup>2</sup>. Inspection speed will increase by more than 10 times when combined with high power light source and high speed data acquisition. Although further optimization is needed, possibility of actinic inspection of EUV mask blanks within a practical inspection time has been demonstrated.
Additive Effects of Chlorin E6 and Metal Ion Binding on the Thermal Stability of Rhodopsin<i>In Vitro</i><sup>†</sup> (2009)

Zinc (Zn(2+)) deficiency causes retinal dysfunctions such as night blindness and neurodegeneration. Because Zn(2+) binds directly to the photoreceptor rhodopsin and alters its stability, the stabilization of rhodopsin may be key to prevention and treatment of retinal dysfunctions. In this paper, we investigated if not only trace metals but also other nutrients may stabilize rhodopsin structure in vitro. Detailed studies of the thermal stability of secondary and tertiary structure of rhodopsin in the presence and absence of the chlorophyll derivative chlorin e6 alone and together with bivalent metal ions Zn(2+), Cu(2+), Fe(2+), Ni(2+), Mg(2+)and Mn(2+) over a temperature range 5-100 degrees C were conducted using circular dichroism and fluorescence spectroscopy. When both chlorin e6 and Zn(2+) are present, a pronounced increase in the thermal stability of overall secondary structure content is observed compared to either compound alone. This additive capacity is also noted with Cu(2+), but not when other metal ions and chlorin e6 are combined.
mCry3A-Selected Western Corn Rootworm (Coleoptera: Chrysomelidae) Colony Exhibits High Resistance and Has Reduced Binding of mCry3A to Midgut Tissue (2016)

Several Bt maize events expressing various insecticidal Cry protein genes have been commercialized for management of western corn rootworm, Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae). We used high efficacy (>99.7%) experimental maize events that express mCry3A for selections under laboratory conditions to develop a western corn rootworm colony resistant to mCry3A at higher levels than published results. The resistance ratio (RR) to mCry3A was >97-fold based on LC 50 values in diet-based bioassays after six generations of selections when compared to that of an unselected Control colony. Using a sublethal seedling assay (SSA) method, we confirmed that the colony had no cross-resistance to maize event DAS-59122-7, which expresses Cry34/35Ab. Reciprocal crosses between the mCry3A-resistant colony and the susceptible colony were performed to test the inheritance of resistance. Larval survival and development evaluated by the SSA method indicated that resistance to mCry3A was inherited autosomally and was incompletely recessive (h = 0.23-0.25). Specific binding of mCry3A to brush border membrane vesicles of midgut tissue revealed reduced binding in the resistant colony when compared to binding in the susceptible colony. This is the first report where resistance in western corn rootworm has been shown to involve reduced binding of a Cry3-class protein in midgut tissue.
Cupid’s Cubicle: Co-Workers’ Reactions to Workplace Romance Characteristics (2011)

Workplace romances are commonplace yet widely debated due to organizational policies, roles, and fairness issues. They involve more than just physical attraction and love; promotions, rewards, and access to information may also be shared. Despite such issues, little research has examined reactions to workplace romances. This experimental study examined the impact of power dynamics (hierarchical/ lateral), sexual orientation of romance participants (homosexual/heterosexual), and organizational role of the observer (manager/employee) on reactions. Hierarchical and homosexual (especially lesbian) workplace romances were perceived to have the most negative impact on the work environment. Only managers found heterosexual, lateral romances as problematic. Implications are discussed.
Stereoselektive Synthese von γ‐Aminocarbonsäureestern (1989)

1,3‐Allylspannungen könnten die hohen Diastereoselektivitäten erklären , die bei der Umsetzung von optisch aktiven α‐Aminosäuren 1 in homochirale γ‐Aminosäureester 3 auftreten. Zwischenstufe bei dieser Synthese sind die über α‐ N,N ‐Dibenzylaminoaldehyde zugänglichen Ester 2 , die durch Cuprataddition stereoselektiv in die Produkte 3 überführt werden. magnified image
The performance of work stealing in multiprogrammed environments (extended abstract) (1998)

No abstract available.
Application of the Brdička Reaction in Determination of Metallothionein in Patients with Tumours (2008)

The connection between the metallothionein (MT) content and the presence of tumor was studied by adsorptive transfer stripping technique and differential pulse voltammetry (Brdicka reaction). The average content of MT in the blood serum of tumour patients was higher than in controls (0.72 ± 0.09 μmol dm−3). In leukemia and lung cancer, the MT content was more than five times higher in comparison with control.
An Oxyferrous Heme/Protein-based Radical Intermediate Is Catalytically Competent in the Catalase Reaction of Mycobacterium tuberculosis Catalase-Peroxidase (KatG) (2009)

A mechanism accounting for the robust catalase activity in catalase-peroxidases (KatG) presents a new challenge in heme protein enzymology. In Mycobacterium tuberculosis, KatG is the sole catalase and is also responsible for peroxidative activation of isoniazid, an anti-tuberculosis pro-drug. Here, optical stopped-flow spectrophotometry, rapid freeze-quench EPR spectroscopy both at the X-band and at the D-band, and mutagenesis are used to identify catalase reaction intermediates in M. tuberculosis KatG. In the presence of millimolar H2O2 at neutral pH, oxyferrous heme is formed within milliseconds from ferric (resting) KatG, whereas at pH 8.5, low spin ferric heme is formed. Using rapid freeze-quench EPR at X-band under both of these conditions, a narrow doublet radical signal with an 11 G principal hyperfine splitting was detected within the first milliseconds of turnover. The radical and the unique heme intermediates persist in wild-type KatG only during the time course of turnover of excess H2O2 (1000-fold or more). Mutation of Met255, Tyr229, or Trp107, which have covalently linked side chains in a unique distal side adduct (MYW) in wild-type KatG, abolishes this radical and the catalase activity. The D-band EPR spectrum of the radical exhibits a rhombic g tensor with dual gx values (2.00550 and 2.00606) and unique gy (2.00344) and gz values (2.00186) similar to but not typical of native tyrosyl radicals. Density functional theory calculations based on a model of an MYW adduct radical built from x-ray coordinates predict experimentally observed hyperfine interactions and a shift in g values away from the native tyrosyl radical. A catalytic role for an MYW adduct radical in the catalase mechanism of KatG is proposed.
A General Spectrochemical Method for Traces of Lead in Iron and Nickel Base Alloys (1963)

A general spectrochemical method for determining trace amounts of lead in a variety of iron- and nickel-base alloys is presented The lead is concentrated by co-precipitation with strontium as sulfate The internal standaid, bismuth sulfate, is added to the dried precipitate The mixture is excited using the dc arc. The coefficient of variation at the 4 ppm level is 14%, and 13% at 40 ppm
The Use of Ceramic Foam Filters in the Production of High Integrity Steels and Ni-base Alloys. (1992)

Inclusion removal using ceramic foam filtration in the casting industry is well known, howeverthe effect of ceramic foam filters on removing inclusions from 'clean' metal is not so well documented. This communication provides a preliminary report of the findings to date. Ceramic foem filters have been used in the production of approximately 3.3 tonne casts using the new Vl DP furnace at Special Melted Products Ltd. Clean metal is supplied by the use of a specially designed launder system preheated to 900'C prior to teeming.
Optical phased-array beam steering controlled by wavelength (2005)

A scheme for optical phased-array beam steering controlled by wavelength is proposed. In this scheme, the optical scanning device consists of arrayed optical waveguides with specific length differences, by which the desired phase slope that results in optical beam steering is formed at the ends of the waveguides and can be changed by varying the optical wavelength. By introducing the concept of irregularly spaced arrays, sidelobes can be dramatically suppressed regardless of large center-to-center interelement spacing. The absolute phase difference between adjacent elements plays a vital role in optical beam steering, and the relation between the nonuniform length difference and the corresponding center-to-center spacing among elements is found.