gebhart/patrepeval huggingface dataset:
Detection of Fungal DNA in Human Body Fluids and Tissues during a Multistate Outbreak of Fungal Meningitis and Other Infections (2013)

Exserohilum rostratum was the major cause of an outbreak of fungal infections linked to injections of contaminated methylprednisolone acetate. Because almost 14,000 persons were exposed to product that was possibly contaminated with multiple fungal pathogens, there was unprecedented need for a rapid throughput diagnostic test that could detect both E. rostratum and other unusual agents of fungal infection. Here we report development of a novel PCR test that allowed for rapid and specific detection of fungal DNA in cerebrospinal fluid (CSF), other body fluids and tissues of infected individuals. The test relied on direct purification of free-circulating fungal DNA from fluids and subsequent PCR amplification and sequencing. Using this method, we detected Exserohilum rostratum DNA in 123 samples from 114 case-patients (28% of 413 case-patients for whom 627 samples were available), and Cladosporium DNA in one sample from one case-patient. PCR with novel Exserohilum-specific ITS-2 region primers detected 25 case-patients with samples that were negative using broad-range ITS primers. Compared to fungal culture, this molecular test was more sensitive: of 139 case-patients with an identical specimen tested by culture and PCR, E. rostratum was recovered in culture from 19 (14%), but detected by PCR in 41 (29%), showing a diagnostic sensitivity of 29% for PCR compared to 14% for culture in this patient group. The ability to rapidly confirm the etiologic role of E. rostratum in these infections provided an important contribution in the public health response to this outbreak.
Cocaine‐induced Increase in Cortical Acetylcholine Release: Interaction with the Hypothalamo—Pituitary—Adrenal Axis (1997)

An influence on drug-taking behaviours of the stress-related hypothalamo-pituitary-adrenal (HPA) axis and its final hormonal mediator, corticosterone, has previously been demonstrated. A role for cortically projecting cholinergic neurons in these behaviours can also be proposed. The experiments presented here examine the effect of the drug of abuse cocaine (15 mg/kg) on the release of acetylcholine (ACh) in the cortex of freely moving rats, using the technique of in vivo microdialysis. To assess a possible modulatory influence of the HPA axis via its final hormonal mediator corticosterone, the cocaine-induced effect on cortical ACh release in intact rats was compared to that in adrenalectomized (ADX) rats, which thus lacked their endogenous source of corticosterone, and in ADX rats in which the cocaine-induced corticosterone peak and/or the basal circadian concentrations of serum corticosterone were simulated by replacement treatments. The results reported here demonstrate that cortical ACh release is greatly increased by cocaine in intact rats; ADX prolongs the return to basal levels of cortical ACh, and the chronic replacement of circadian levels of corticosterone normalizes this effect. In contrast, during the plateau period of cocaine-induced increased cortical ACh release, where no effect of ADX is evident, rats with chronic replacement of corticosterone show an attenuated cocaine-induced cortical ACh release, and the acute replacement of the cocaine-induced corticosterone secretion further attenuates this response. These results demonstrate that cocaine stimulates cortically projecting cholinergic neurons, and that the HPA hormone corticosterone modulates this interaction in a complex manner which merits further investigation.
Wideband Circularly Polarized Stacked Microstrip Antennas (2007)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> A simple technique is developed to improve the axial ratio (AR)-bandwidth and quality of circularly polarized stacked microstrip antennas (CPSMAs) using a new C-type single feed. The proposed antenna has been optimized and fabricated, and the computed results agree very well with measurements. The antenna has a 3 dB AR bandwidth of 13.5%, gain is more than 7.5 dBi over the 3 dB AR bandwidth and the 10 dB return-loss bandwidth is 21%. The proposed feed optimization technique is useful for rapid design of circular polarized stacked microstrip antennas. </para>
Effect of Small Hydrogen Jet Flame on Augmentation of Lean Combustion (1993)

<div class="htmlview paragraph">Cleaner and more efficient combustion engines have been expected to suppress the consumption of petroleum resources and to save the environment of the earth. From such a standpoint, lean mixture has been thought to be suitable. Recently, the cars equipping engines that can burn at equivalence ratio of approximately 0.6 have been developed. The mixture whose strength is lower than 0.6 is thought not to be appropriate for internal combustion engines because such engine cannot afford stable driving. So, the mixture whose strength is lower than 0.6 must be augmented by any new devices. Several jet ignition methods such as plasma jet igniter have been proposed. Most of them are thought that the principal factor of augmentation is radicals. Strong jet is also a factor of augmentation. Authors had the latter standpoint and proposed hydrogen jet igniter. It uses small amount of hydrogen. The combustion processes are similar to that ignited by plasma jet. It is very important to make clear the mechanism of augmentation by such jet igniters to adapt them to the actual engines. In this report, the fundamental characteristics of the hydrogen jet igniter are briefly mentioned and the mechanism of augmentation is investigated. The role of radicals is separated from the role of flame jet speeds.</div>
The laser rangefinder (1966)

The recently developed laser rangefinder is a truly portable instrument whose accuracy on readings of up to 10 km is within ±10m.
Men at, work (2000)

Although the number of practice nurses is expanding rapidly, very few of them are men. Jenny MacKenzie talks to two mould breakers
Inhibition of gingival fibroblast growth by Bacteroides gingivalis (1987)

Human gingival fibroblasts were exposed in culture to cell extracts of different black-pigmented Bacteroides species, and their growth was monitored by determining thymidine uptake and counting cells. Of the Bacteroides species tested (B. gingivalis, B. asaccharolyticus, and B. intermedius), B. gingivalis gave the extract with the strongest inhibitory effect on fibroblast thymidine uptake. Linear inhibition reaching 80% of the control level was obtained with a dose of 100 micrograms of B. gingivalis extract protein per ml. The effect of B. asaccharolyticus resembled that of B. gingivalis, but even at the highest dose tested B. intermedius had only a slight inhibitory effect. When fibroblasts were counted after 2- and 4-day exposures to B. gingivalis extracts, a clear depression in the number of fibroblasts was found. The effects of extracts obtained from early and late growth phases of B. gingivalis cultures were similar. A fraction of B. gingivalis consisting essentially of lipopolysaccharides (LPSs) was obtained by degrading the extract proteins with proteinase K. Silver staining of polyacrylamide gels revealed a LPS pattern with a molecular mass ranging from 37 to 60 kilodaltons. This LPS-rich fraction caused inhibition of thymidine uptake by gingival fibroblasts similar to that caused by the native extract alone. Thus, the inhibition of gingival fibroblast growth by B. gingivalis appeared to be LPS mediated. This inhibitory effect of B. gingivalis on oral fibroblast growth may be a virulence factor of this bacterium.
Pulp response to direct capping with an adhesive system. (2000)

Both pulp capping materials allowed pulp repair, characterized by reorganization of a new odontoblast cell layer underlying the dentin bridge formation. However, P&B 2.0 promoted a large zone of cell-rich fibrodentin matrix deposition between the pulp capping material and the dentin bridge, which was deposited far from the pulp exposure site. On the other hand, pulps capped with ZOE showed dentin bridging immediately subjacent to the pulp capping material. In those samples in which microleakage occurred between dental material and cavity walls there was a persistent inflammatory reaction and lack of complete pulp repair.
The inhibition of diacylglycerol-stimulated intracellular phospholipases by phospholipids with a phosphocholine-containing polar group. A possible physiological role for sphingomyelin (1985)

Phosphatidylinositol phosphodiesterase activated by diacylglycerol is substantially inhibited by all phospholipids containing a phosphocholine head group, including phosphatidylcholine, hydrogenated phosphatidylcholine, choline plasmalogen, lysophosphatidylcholine, lysocholine plasmalogen, sphingomyelin and sphingosylphosphocholine. The sphingosine-containing phospholipids are the most inhibitory. Phosphatidic acid does not inhibit, and phosphatidylethanolamine activates the hydrolysis still further. Sphingomyelin is highly inhibitory to a diacylglycerol-stimulated intestinal mucosal phospholipase A2, or a liver lysosomal phospholipase A1 + A2, both hydrolysing a phosphatidylcholine substrate. Sphingomyelin [20% molar (20 mol of sphingomyelin/80 mol of phosphatidylethanolamine)] activates phosphatidylethanolamine hydrolysis by intestinal mucosal phospholipase A2, and then at higher concentrations (40% molar) substantially inhibits the activity. The results are discussed in relation to possible molecular reorganizations brought about in the hydrated phospholipid substrate complex, and in particular the possible stabilizing role of sphingomyelin in the maintenance of membrane structure, and hence in the modulation of phospholipase activity.
Cocatalyst Influence in Selective Oligomerization:  Effect on Activity, Catalyst Stability, and 1-Hexene/1-Octene Selectivity in the Ethylene Trimerization and Tetramerization Reaction (2007)

The trimerization and tetramerization of ethylene to 1-hexene and 1-octene with a Cr/PNP/AlEt3 catalyst system, in combination with a variety of cocatalysts, has been investigated. The cocatalysts B(C6F5)3 (1), Al(OC6F5)3 (2), [(Et2O)2H][Al(OC6F5)4] (3), [Ph3C][Ta(OC6F5)6] (4), (Et2O)Al{OCH(C6F5)2}3 (5), (Et2O)Al{OC(CF3)3}3 (6), [Ph3C][Al{OC(CF3)3}4] (7), [Ph3C][AlF{OC(CF3)3}3] (8), [Ph3C][{(F3C)3CO}3Al−F−Al{OC(CF3)3}3] (9), and [Ph3C][CB11H6Br6] (10) have been evaluated. The relative selectivity to 1-hexene and 1-octene obtained shows a strong dependence on the nature of the cocatalyst, and a range of selectivities from <5% C8 (90% C6) to 72% C8 have been observed. The stability of several cocatalysts toward AlEt3 has been studied, and the poor performance of 1 and 2 is linked to degradation of the cocatalyst through ethyl group exchange with AlEt3. In contrast, the [Al{OC(CF3)3}4]- anion in 7 is much more stable and gives rise to a highly active and longer lived catalyst. The overall productivity and selectivity of the catalyst is dependent upon both cocatalyst stability and the nature of the anion present, and a reason for this effect has been suggested. Selectivity control by the cocatalyst has been ascribed to interaction of the anion with the active Cr center.
Differences in Employee Multidimensional Health by Gender, Age, and Educational Level (2008)

SUMMARY Multidimensional health was assessed in a sample of university employees including faculty, staff, and administrators (N = 955). Seven areas of self-reported health were measured: physical, environmental, social, emotional, intellectual, spiritual, and occupational wellness. A gender by age by educational level between-subjects MANOVA revealed a significant gender by education interaction (p = .001), and significant main effects (p < .001) for gender, age, and educational level. Men reported as significantly healthier than women on social and intellectual health. Women reported as significantly healthier than men on physical health. In general, response trends indicate that older participants reported greater health across dimensions than younger participants, and more educated persons reported greater health across dimensions than less educated persons. Recommendations for how these findings can direct primary prevention programming are offered.
A rapid benchtop NMR method for determination of droplet size distributions in food emulsions (2007)

Abstract The determination of water and oil droplet size distributions in food emulsions by low‐field NMR has the advantage of a simple and non‐perturbing sample preparation. Furthermore, NMR performs very well with respect to precision. The current implementation on most benchtop NMR spectrometers deploys a variation of gradient duration and requires continuous corrections for gradient imbalances, thus making the whole procedure a time‐consuming one. By using variation of gradient strength and further stretching the capability of commercial benchtop NMR spectrometers, both water and oil droplet sizes can be measured in a more rapid manner, typically two to three times faster. The measured droplet size distributions are equivalent to those assessed by the current (slow) method, for both O/W and W/O emulsions. Furthermore, the rapid method shows a good performance with respect to precision. In addition, the method is able to determine droplet sizes in samples with much smaller amounts of dispersed phase.
An empirical study of static program slice size (2007)

This article presents results from a study of all slices from 43 programs, ranging up to 136,000 lines of code in size. The study investigates the effect of five aspects that affect slice size. Three slicing algorithms are used to study two algorithmic aspects: calling-context treatment and slice granularity. The remaining three aspects affect the upstream dependencies considered by the slicer. These include collapsing structure fields, removal of dead code, and the influence of points-to analysis. The results show that for the most precise slicer, the average slice contains just under one-third of the program. Furthermore, ignoring calling context causes a 50% increase in slice size, and while (coarse-grained) function-level slices are 33% larger than corresponding statement-level slices, they may be useful predictors of the (finer-grained) statement-level slice size. Finally, upstream analyses have an order of magnitude less influence on slice size.
JOHN C. ANDERSON (1902)

Research Article| January 01 1902 JOHN C. ANDERSON A. H. JOHNSON A. H. JOHNSON Search for other works by this author on: This Site PubMed Google Scholar Annual Publication of the Historical Society of Southern California and of the Pioneers of Los Angeles County (1902) 5 (3): 308–309. https://doi.org/10.2307/41169187 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Cite Icon Cite Search Site Citation A. H. JOHNSON; JOHN C. ANDERSON. Annual Publication of the Historical Society of Southern California and of the Pioneers of Los Angeles County 1 January 1902; 5 (3): 308–309. doi: https://doi.org/10.2307/41169187 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentSouthern California Quarterly Search This content is only available via PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
A distinct multicytokine profile is associated with anti-cyclical citrullinated peptide antibodies in patients with early untreated inflammatory arthritis. (2004)

Early untreated inflammatory arthritis can be categorized into distinct subgroups based on cytokine profiles. These subgroups are associated with CCP and RF autoantibodies. Integration of cytokine profiles with autoantibody status may assist prognostication and treatment decisions in these patients.
Medicinal plants of South Africa (1997)

Medicinal plants of South Africa is a guide to the most commonly utilised medicinal plants in South Africa. The title includes: Detailed species descriptions of 132 medicinal plants. Each entry includes the following information: a description of the plant, the plant parts used, medicinal uses, preparation and dosage, active ingredients, pharmacological effects, and distribution. Distribution maps are included for each plant. More than 500 excellent full-colour photographs that will assist in the identification of medicinal plants and plant parts. Introductory chapters on cultural aspects of healing, methods of collection and storage, dosage forms and methods of preparation, and methods of administration. Plants listed according to ailments and a glossary of medical terms.
Enhanced Resolution in Nanoscale NMR via Quantum Sensing with Pulses of Finite Duration (2017)

The nitrogen-vacancy (N-V) color center in diamond is an enormously important platform for the\ndevelopment of quantum sensors, including for single-spin and single-molecule NMR. Detection of weak\nsingle-spin signals is greatly enhanced by repeated sequences of microwave pulses; in these dynamicaldecoupling\ntechniques, the key control parameters swept in the experiment are the time intervals, τ,\nbetween pulses. Here, we show that, in fact, the pulse duration tp offers a powerful additional control\nparameter. While a non-negligible tp was previously considered simply a source of experimental error, we\nelucidate here the underlying quantum dynamics: we identify a landscape of quantum-state crossings which\nare usually inactive (closed) but may be controllably activated (opened) by adjusting tp from zero. We\nidentify these crossings with recently observed but unexpected dips (so-called spurious dips) seen in the\nquantum coherence of the N-V spin. With this new understanding, both the position and the strength of\nthese sharp features may be accurately controlled; they coexist with the usual broader coherence dips of\nshort-duration microwave pulses, but their sharpness allows for higher-resolution spectroscopy with\nquantum diamond sensors, or their analogs.
Learning static occlusions from interactions with moving figures (2005)

We present a simple and efficient algorithm for determining the position of static occluding bodies within a scene viewed by one or more static cameras. All information about the occluding bodies is derived from the perimeter of a figure moving through the scene. Once the positions of the occlusions are learned, successful reasoning about the observability of future figures in the scene is demonstrated. The method is extended to derive an estimate of the 3D position of the occluding bodies from multiple views. Several experimental results are described.
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung (1998)

Mammalian lungs begin as an outpocket of the foregut, and depend on multiple stages of branching morphogenesis and alveogenesis to reach their final form. An examination of fgf receptor gene expression indicated that all four receptors (fgfr-1 to fgfr-4) are expressed in postnatal lungs at varying levels. We show that mice homozygous for a targeted mutation of fgfr-4 exhibited no overt abnormalities in the lungs or any other organ. However, mice doubly homozygous for disruptions of the fgfr-3 and fgfr-4 genes display novel phenotypes not present in either single mutant, which include pronounced dwarfism and lung abnormalities. Lungs of fgfr-3(-/-)fgfr-4(-/- )animals, which are normal at birth, are completely blocked in alveogenesis and do not form secondary septae to delimit alveoli. Consequently, air spaces in the lung are expanded and no alveoli can be seen. The mutant lungs failed to downregulate postnatal elastin deposition despite their normal levels of surfactant expression and cell proliferation. These data revealed a cooperative function of FGFR-3 and FGFR-4 to promote the formation of alveoli during postnatal lung development.
Sulfur trioxide removal performance of alkaline sorbents injection in the temperature range 400–705 °C: a pilot‐scale study (2019)

Abstract BACKGROUND Sulfur trioxide (SO 3 ) in coal combustion flue gas can adversely affect power plant equipment and the environment. In this work, the removal of SO 3 with typical sodium (Na), magnesium (Mg) and calcium (Ca)‐based sorbents was investigated at a pilot‐scale facility in the temperature range 400–705 °C. RESULTS The injection of sodium bicarbonate (NaHCO 3 ) showed the highest SO 3 removal efficiency, which was ∼85% at the sorbent/SO 3 molar ratio of 2 with the gas residence time of 1 s. This is much higher than that of calcium hydroxide (Ca(OH) 2 ) (∼25%) and magnesium hydroxide (Mg(OH) 2 ) (∼30%). The removal efficiency of Mg(OH) 2 and Ca(OH) 2 increased with increasing the reaction temperature from 400 to 705 °C. With the addition of 800 ppm sulfur dioxide (SO 2 ), the adsorption of SO 3 on alkaline sorbents was inhibited due to the competitive adsorption, which caused SO 3 removal efficiency to decrease by 5–12.5%. When injecting the sorbents in slurry form, the removal efficiency was found to be two times higher than that in powder form. CONCLUSION NaHCO 3 is the most effective sorbent comparing to Mg(OH) 2 and Ca(OH) 2 . To increase the SO 3 removal efficiency, the alkaline sorbents should be injected in the high temperature zone in flue gas. It is recommended to inject the sorbents in slurry form instead of injecting powders directly to achieve high removal efficiency. © 2019 Society of Chemical Industry
New Techniques for Preserving Global Structure and Denoising with Low Information Loss in Single-Image Super-Resolution (2018)

This work identifies and addresses two important technical challenges in single-image super-resolution: (1) how to upsample an image without magnifying noise and (2) how to preserve large scale structure when upsampling. We summarize the techniques we developed for our second place entry in Track 1 (Bicubic Downsampling), seventh place entry in Track 2 (Realistic Adverse Conditions), and seventh place entry in Track 3 (Realistic difficult) in the 2018 NTIRE Super-Resolution Challenge. Furthermore, we present new neural network architectures that specifically address the two challenges listed above: denoising and preservation of large-scale structure.
Probiotic Properties of Lyophilized Cell Free Extract of Lactobacillus casei (2013)

Employing the LPE as a new approach, gives novel concept of probiotic-products in food and medical marketing.
Coordinated multipoint multiuser-MIMO transmissions over backhaul-constrained mobile access networks (2011)

We investigate coordinated multipoint (CoMP) multiuser multiple-input-and-multiple-output (multiuser-MIMO) downlink transmissions over mobile access networks yielding different backhaul constraints. The larger number of base stations (BSs) participating in CoMP, the higher user throughput can be expected if there is no constraint in mobile backhaul networks. Limited capacity and latency in mobile backhaul networks impose constraints on the number of BSs that can actually participate in CoMP. We propose a CoMP system architecture with multiple clustering steps that that takes into account these backhaul constraints and enables to avoid selecting BSs which do not have enough backhaul network capability. The system-level simulation shows how much performance gain user can expect by improving backhaul network capability.