gebhart/patrepeval huggingface dataset:
Silent-PIM: Realizing the Processing-in-Memory Computing With Standard Memory Requests (2021)

The Deep Neural Network (DNN), Recurrent Neural Network (RNN) applications, rapidly becoming attractive to the market, process a large amount of low-locality data; thus, the memory bandwidth limits their peak performance. Therefore, many data centers actively adapt high-bandwidth memory like HBM2/HBM2E to resolve the problem. However, this approach would not provide a complete solution since it still transfers the data from the memory to the computing unit. Thus, processing-in-memory (PIM), which performs the computation inside memory, has attracted attention. However, most previous methods require the modification or the extension of core pipelines and memory system components like memory controllers, making the practical implementation of PIM very challenging and expensive in development. In this article, we propose a Silent-PIM that performs the PIM computation with standard DRAM memory requests; thus, requiring no hardware modifications and allowing the PIM memory device to perform the computation while servicing non-PIM applications' memory requests. We can achieve our design goal by preserving the standard memory request behaviors and satisfying the DRAM standard timing requirements. In addition, using standard memory requests makes it possible to use DMA as a PIM's offloading engine, resulting in processing the PIM memory requests fast and making a core perform other tasks. We compared the performance of three Long Short-Term Memory models (LSTM) kernels on real platforms, such as the Silent-PIM modeled on the FPGA, GPU, and CPU. For (p ×512) ×(512 ×2048) matrix multiplication with a batch size p varying from 1 to 128, the Silent-PIM performed up to 16.9x and 24.6x faster than GPU and CPU, respectively, p=1, which was the case without having any data reuse. At p=128, the highest data reuse case, the GPU performance was the highest, but the PIM performance was still higher than the CPU execution. Similarly, at (p ×2048) element-wise multiplication and addition, where there was no data reuse, the Silent-PIM always achieved higher than both CPU and GPU. It also showed that when the PIM's EDP performance was superior to the others in all the cases having no data reuse.
The effects of plasma exposure and vacuum ultraviolet irradiation on photopatternable low-k dielectric materials (2013)

The effects of plasma exposure and vacuum-ultraviolet (VUV) irradiation on photopatternable low-k (PPLK) dielectric materials are investigated. In order to examine these effects, current-voltage measurements were made on PPLK materials before and after exposure to a variety of inert plasma-exposure conditions. In order to examine the effects of photon irradiation alone, PPLK samples were also exposed to monochromatic synchrotron radiation with 10 eV photon energy. It was found that plasma exposure causes significant degradation in electrical characteristics, resulting in increased leakage-currents and decreased breakdown voltage. X-ray photoelectron spectroscopy measurements also show appreciable carbon loss near the sample surface after plasma exposure. Conversely, VUV exposure was found to increase breakdown voltage and reduce leakage-current magnitudes.
Ultrafast all-optical magnetic switching in NaTb(WO4)2 (2010)

The operation of an all-optical magnetic switching based on the paramagnetic NaTb(WO4)2 crystals is carried out by the time-resolved magneto-optical Faraday effect. Our results demonstrate that the switching time can be as fast as ∼500 fs at room temperature. The switching amplitude shows a linear dependence on the excitation intensity, which is proportional to the magnetization induced by the circularly polarized light. Based on the inverse Faraday effect in magneto-optical crystal, the switching mechanisms arising from circular dichroism and birefringence are discussed. By tailoring the magneto-optical properties of NaTb(WO4)2 crystal, the switching magnitude can be modulated.
ChemInform Abstract: Syntheses of New Pyridonecarboxylic Acid Derivatives Containing 1‐ or 2‐Naphthyl Substituents at N‐1 and Their anti‐HIV‐RT Activities. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Protein evolution: structure‐function relationships of the oncogene beta‐catenin in the evolution of multicellular animals (2003)

Beta-catenin functions as a cytoskeletal linker protein in cadherin-mediated adhesion and as a signal mediator in wnt-signal transduction pathways. We use a novel integrative approach, combining evolutionary, genomic, and three-dimensional structural data to analyze and trace the structural and functional evolution of beta-catenin genes. This approach also enabled us to examine the effects of gene duplication on the structure and function of beta-catenin genes in Drosophila, C. elegans, and vertebrates. By sampling a large number of different taxa, we identified both ancestral and derived motifs and residues within the different regions of the beta-catenin proteins. Projecting amino acid substitutions onto the three- dimensional structure established for mouse beta-catenin, we identified specific domains that exhibit loss and gain of selective constraints during beta catenin evolution. Structural changes, changes in the amino acid substitution rate, and the appearance of novel functional domains in beta-catenin can be mapped to specific branches on the metazoan tree. Together, our analyses suggest that a single, beta-catenin gene fulfilled both adhesion and signaling functions in the last common ancestor of metazoans some 700 million years ago. In addition, gene duplications facilitated the evolution of beta-catenins with novel functions and allowed the evolution of multiple, single-function proteins (cell adhesion or wnt-signaling) from the ancestral, dual-function protein. Integrative methods such as those we have applied here, utilizing the 'natural experiments' present in animal diversity, can be employed to identify novel and shared functional motifs and residues in virtually any protein among the proteomes of model systems and humans.
Transient Growth and Triggering in the Horizontal Rijke Tube (2010)

This theoretical paper examines a non-normal and non-linear model of a horizontal Rijke tube. Linear and non-linear optimal initial states, which maximize acoustic energy growth over a given time from a given energy, are calculated. It is found that non-linearity and non-normality both contribute to transient growth and that, for this model, linear optimal states are only a good predictor of non-linear optimal states for low initial energies. Two types of non-linear optimal initial state are found. The first has strong energy growth during the first period of the fundamental mode but loses energy thereafter. The second has weaker energy growth during the first period but retains high energy for longer. The second type causes triggering to self-sustained oscillations from lower energy than the first and has higher energy in the fundamental mode. This suggests, for instance, that low frequency noise will be more effective at causing triggering than high frequency noise.
Comparison of a Tranquilizer and a Psychic Energizer (1960)

Seventy-five hyperactive, poorly integrated children were divided into groups of 25 for a comparative study of the effects of two drugs on their behavior. One group received a psychic energizer (deanol) in doses of 50 mg. twice daily; the second received a sedative (trimeglamide) in doses of 250 mg. twice daily; the third received a placebo. Systematic observations were made before and after the period of medication. Analysis of the results showed that deanol generally increased the child's power of concentration as manifested in integrative tasks such as puzzle-solving. Trimeglamide generally alleviated tantrums and diffuse hyperactivity. The placebo group did not manifest either of these effects. The author suggests the concomitant use of these two drugs in overly aggressive, emotionally disturbed children.
Organically Modified Transition-Metal Oxide Mesoporous Thin Films and Xerogels (2004)

Organic molecules have been incorporated into the pore system of mesoporous TiO2 and ZrO2 xerogels and thin films. Surface-modifying functions include alkyl, aryl, amino, sulfonate, thiol, and polyol. Phosphate, phosphonate, carboxylate, and polyphenol were used as grafting groups. The incorporation of these functions into the mesoporous network (typically 2−8 μmol/m2) was monitored by crossing FTIR and EDS. In particular, the cases of dihexadecyl phosphate, monododecyl phosphate, 3-nitrophthalic acid, TIRON (disodium 1,2-dihydroxybenzene, 3,5-disulfonate), and thiol-bearing carboxylates are discussed. Uptake experiments suggest that the pore structure plays a key role in the accessibility of the pore system. Leaching experiments in different solvents and conditions were performed to assess the anchoring of the grafted functions. This permits tailoring of the molecule grafting, from firmly anchored functions to groups with controlled lability.
Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons (2002)

Signaling by brain-derived neurotrophic factor (BDNF) via the TrkB receptor, or by neurotrophin-3 (NT3) through the TrkC receptor support distinct populations of sensory neurons. The intracellular signaling pathways activated by Trk (tyrosine kinase) receptors, which in vivo promote neuronal survival and target innervation, are not well understood. Using mice with TrkB or TrkC receptors lacking the docking site for Shc adaptors (trkB(shc/shc) and trkC(shc/shc) mice), we show that TrkB and TrkC promote survival of sensory neurons mainly through Shc site-independent pathways, suggesting that these receptors use similar pathways to prevent apoptosis. In contrast, the regulation of target innervation appears different: in trkB(shc/shc) mice neurons lose target innervation, whereas in trkC(shc/shc) mice the surviving TrkC-dependent neurons maintain target innervation and function. Biochemical analysis indicates that phosphorylation at the Shc site positively regulates autophosphorylation of TrkB, but not of TrkC. Our findings show that although TrkB and TrkC signals mediating survival are largely similar, TrkB and TrkC signals required for maintenance of target innervation in vivo are regulated by distinct mechanisms.
Studies on the constituents of Artemisia argyi LEVL et VANT. (1984)

Twelve compounds were isolated from Artemisia argyi, LEVL et VANT (Compositae) collected in China : ethyl palmitate, ethyl oleate, ethyl linoleate, lupenone, lupenyl acetate, α-amyrin acetate, β-amyrin acetate, glutinone, fernenone, 24-methylene-cycloartanone, simiarenol and trans-phenylitaconic acid. This is the first report of the isolation of trans-phenylitaconic acid from a natural souce.
Edge modified vector quantization for image compression (2003)

A new adaptive source coding technique called edge modified vector quantization (EMVQ) is introduced. By using EMVQ, an image is encoded in two stages: coarse image coding and edge modification. The redundancies in the smooth area are further reduced by applying large block segmentation, hierarchical VQ and finite state prediction. Sharp edges are well preserved by compensation of their encoding quantization error. A high compression ratio was achieved and the reconstructed images still had satisfactory perceptual quality. The EMVQ coding results are demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Filtration and recirculation of early amniotic fluid. Evaluation of cell cultures from 100 diagnostic cases (1993)

Due to the low cell concentration, cultures from early amniotic fluid specimens usually require 2-3 weeks in culture prior to karyotyping. The purpose of this study was to evaluate the culture quality of amniotic fluid cells from early pregnancy, obtained by a new filter technique. The hypothetical advantage of the technique was that the increased cell yield might reduce the culture time before karyotyping. Culture quality was assessed by the number of colonies, the percentage of colonies containing mitoses in filter and control cultures, and the culture time. The setting was a consecutive clinical trial. One hundred samples were obtained from ongoing pregnancies at 11-14 weeks of gestation (mean 12.8 weeks). By circulating a mean of 26 ml of amniotic fluid through a cell filter system leading the cell-free fluid back to the amniotic cavity, the cell yield was increased in the sample of 7 ml corresponding to the dead space of the filter system. The culture results were compared with control cultures from 5 ml samples drawn from the same pregnancies prior to recirculation. The cultures from the first flushing of the filter system yielded 2.6 times more colonies and in total 4.2 times more colonies were found in the three cultures grown from each filter sample when compared with the control cultures. Moreover, the filter cultures showed significantly more colonies with mitoses. The mean culture time was 8.0 days for the filter cultures, from which the karyotypes were analysed. The controls would have needed more time in culture to fulfil the diagnostic criteria for karyotyping. One case of 47,XY,+21 was found; the rest had normal karyotypes. We conclude that the filter technique improves the culture quality of early amniotic fluid samples and allows early arrest of the cultures.
Direct Thrust Measurement of an Electron Cyclotron Resonance Plasma Thruster (2018)

Direct thrust measurements of an electron cyclotron resonance plasma thruster are performed with a thrust balance. The thruster performances are deduced, and the influence of power and mass-flow rate is studied. The measured thrust is around 1 mN for 50 W of microwave power input and of xenon, corresponding to 1000 s of specific impulse and 11% of total efficiency. It is found that the thrust is increased by 25% when the walls of the plasma source are covered with a dielectric layer. Comparisons are made between the direct thrust measurements and the indirect thrust measurements obtained with electrostatic probes in the plasma beam.
Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis (2004)

(1) Subcutaneous administration of L salivarius 118 significantly attenuated colitis in the IL-10 KO model and suppressed collagen induced arthritis, suggesting that the oral route may not be essential for probiotic anti-inflammatory effects and that responses are not disease specific. (2) The probiotic effect was associated with reduced production of proinflammatory (T helper 1) cytokines and maintained production of anti-TGF-beta.
A knowledge‐based system for process family planning (2013)

Purpose The purpose of this paper is twofold. First, it is to introduce a knowledge‐based system for planning processes for families of final products, instead of component items, be they parts or assemblies. Second, it is to demonstrate the feasibility and potential of a prototypical system developed for planning processes families for truck families from a multinational company. Design/methodology/approach The authors first identify the challenges in planning process families, including data and knowledge representation and constraint handling. To accommodate these challenges, the paper adopts the integrated product and process structure (IP 2 S) and colored timed Petri nets (CTPNs) in the proposed knowledge‐based process family planning system. On top of the IP 2 S and CTPNs, XML‐based knowledge representation is employed to alleviate the difficulties in modelling complex product and process family data and planning knowledge while enabling information exchange across different operating platforms. In addition, in accordance with the correspondence between PNs and knowledge‐based systems, a mechanism is designed to cope with the generation of production rules, which model constraints. Findings The proposed system is able to automatically generate production processes for customized products. At a higher level, such production processes provide input (e.g. operations, machines) to downstream activities for planning process details to manufacture component parts or component assemblies. Research limitations/implications Traditional trial and error approaches to planning processes limit production performance improvement when companies need to timely produce diverse customized products. Knowledge‐based systems should be developed to help companies better plan production processes based on the available manufacturing resources. Originality/value Unlike most reported studies addressing either detailed process planning or assembly planning for component parts or component assemblies, this study tackles process planning for final products, in attempting to maintain production efficiency from a holistic view.
Binding of magnesium and calcium ions to the phosphoglycoprotein phosvitin (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBinding of magnesium and calcium ions to the phosphoglycoprotein phosvitinKart Grizzuti and Gertrude E. PerlmannCite this: Biochemistry 1973, 12, 22, 4399–4403Publication Date (Print):October 1, 1973Publication History Published online1 May 2002Published inissue 1 October 1973https://pubs.acs.org/doi/10.1021/bi00746a016https://doi.org/10.1021/bi00746a016research-articleACS PublicationsRequest reuse permissionsArticle Views147Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Case Report (2016)

Bazex syndrome, a rare paraneoplastic syndrome characterized by psoriasiform eruptions, palmoplantar keratosis, and symmetric onychodystrophy, is most prevalent with squamous cell carcinomas of the upper aerodigestive tract.Here, we reported an uncommon case of Bazex syndrome about an 83-year-old man with pulmonary adenocarcinoma and osseous metastasis, Physical examination found psoriasiform eruptions on the nose, cheeks, ears, knees, and the dorsa of interphalangeal joints, along with plantar keratosis and symmetric onychodystrophy involving hands and feet. Imaging analyses pulmonary adenocarcinoma with both local metastatic nodules and osseous metastasis.Symptomatic treatment with topical corticosteroids and oral retinoids showed no improvement. A 4-month follow-up showed that Gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, successfully reduced primary tumor size and alleviated cutaneous lesions.Our report here highlighted a potential correlation between pulmonary adenocarcinoma and Bazex syndrome, which is characterized by hallmark nail destruction and preferential involvement of body extremities. Moreover, etiological therapy against underlying malignancy is essential for treating paraneoplastic Bazex syndrome.
Statistical ranking in tactical generation (2006)

In this paper we describe and evaluate several statistical models for the task of realization ranking, i.e. the problem of discriminating between competing surface realizations generated for a given input semantics. Three models (and several variants) are trained and tested: an n-gram language model, a discriminative maximum entropy model using structural information (and incorporating the language model as a separate feature), and finally an SVM ranker trained on the same feature set. The resulting hybrid tactical generator is part of a larger, semantic transfer MT system.
An Advanced Closed-Loop Control to Improve the Performance of Hybrid Stepper Motors (2016)

This paper presents an effective closed-loop control approach for a stepper motor. The proposed approach consists of motor parameter identification, closed-loop current control, closed-loop position control, and damping control. The presented implementation achieves accurate position, high torque, and smooth speed. By using an improved proportional-integral current control algorithm, this approach not only guarantees the current tracking performance but also increases the bandwidth during the speed response. The advanced position controller achieves both high torque and the synchronous condition of the motor after a loss of synchronism occurs. In addition, this method applies an effective speed damping method to remove resonance at low speed and reduce vibration at high speed. All the proposed algorithms were implemented on an industrial test-bench. The experimental results demonstrate the validity of the proposed approach for practical applications.
Improving object detection using 3D spatial relationships (2013)

Reliable object detection is one of the most significant hurdles that must be overcome to develop useful household robots. Overall, the goal of this work is to demonstrate how effective 3D qualitative spatial relationships can be for improving object detection. We show that robots can utilize 3D qualitative spatial relationships to improve object detection by differentiating between true and false positive detections. The main body of the thesis focuses on an approach for improving object detection rates that identifies the most likely subset of 3D detections using seven types of 3D relationships and adjusts detection confidence scores to improve the average precision. These seven 3D qualitative spatial relationships are adapted from 2D qualitative spatial reasoning techniques. We learn a model for identifying the most likely subset using a structured support vector machine [Tsochantaridis et al., 2004] from examples of 3D layouts of objects in offices and kitchens. We produce 3D detections from 2D detections using a fiducial marker and images of a scene and show our model is successful at significantly improving overall detection rates on real world scenes of both offices and kitchens. After the real world results, we test our method on synthetic detections where the properties of the 3D detections are controlled. Our approach improves on the model it was based upon, that of [Desai et al., 2009], by utilizing a branch and bound tree search to improve both training and inference. Our model relies on sufficient true positive detections in the training data or good localization of the true positive detections. Finally, we analyze the cumulative benefits of the spatial relationships and determine that the most effective spatial relationships depend on both the scene type and localization accuracy. We demonstrate that there is no one relationship that is sufficient on its own or always outperforms others and that a mixture of relationships is always useful.