gebhart/patrepeval huggingface dataset:
A new teletext decoder with advanced OSD features for wide screen TV (1993)

A decoder that is ready to meet the challenge of higher levels of teletext transmission proposed for Europe is described. Its display capabilities are better than those of most OSD (on-screen display) devices. It overcomes the problems associated with using existing teletext decoders for OSDs. A number of new features are incorporated to make it particularly attractive for wide-screen TVs. The device breaks away from the conventional 40 characters per row format by offering up to 63 characters per row. Examples of how the extra character space might be used are shown.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) (2014)

Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through 'preventive chemotherapy' programmes to school-aged children or at-risk populations. In addition, preschool-aged children are now recognized as a vulnerable population and a group for targeted treatment, but they may be difficult to dose correctly with the available product--a racemate, based on the biologically active enantiomer (R-praziquantel) and the inactive distomer (S-praziquantel), which contributes the bitter taste and doubles the size of the tablets. Hence, a paediatric formulation is required, possibly enantiomerically pure. Developing such a product and extending its use to younger children should be pharmacologically guided, but limited data exist on pharmacokinetics and pharmacokinetic/pharmacodynamic correlations for praziquantel. This article presents available data on the chemistry, pharmacokinetics and pharmacodynamics of praziquantel, as well as R-praziquantel, and points to gaps in our knowledge.
Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro (1994)

Two panels of monoclonal antibodies (MAbs) specific for the influenza A virus PA and PB2 polypeptides have been obtained from mice immunized with denatured proteins produced in Escherichia coli. All MAbs (13 specific for the PA polypeptide and 8 specific for the PB2 protein) reacted to the corresponding influenza virus protein in Western blotting (immunoblotting), immunoprecipitation, and immunofluorescence assays. To gain information about the roles of the nucleoprotein (NP) and PB2 and PA proteins during viral mRNA synthesis, the 21 anti-P antibodies and 3 anti-NP antibodies (J. A. López, M. Guillen, A. Sánchez-Fauquier, and J. A. Melero, J. Virol. Methods 13:255-264, 1986) were purified and tested for their ability to inhibit the transcriptase activity associated with viral cores purified from virions. Four of the antibodies (one anti-PB2 and the three anti-NP MAbs) inhibited transcription by more than 50% compared with unrelated control antibodies. The inhibitory effect was not due to a nonspecific effect of the antibody preparations, because these MAbs did not inhibit transcription when tested on influenza B virus nucleocapsids, which are not recognized by the antibodies. To determine whether the antibodies were acting on an early transcription step, transcription reactions were carried out in the presence of globin mRNA (a mixture of alpha- and beta-globin chains) and only one labeled nucleoside triphosphate (either GTP or CTP). The results obtained showed that MAbs to the PB2 and NP polypeptides interfered with the initiation step of mRNA-primed transcription. The implications of these results regarding initiation of viral mRNA synthesis are discussed.
Depth Video Enhancement for Haptic Interaction Using a Smooth Surface Reconstruction (2006)

We present a depth video enhancement algorithm in order to provide high quality haptic interaction. As the telecommunication technology emerges rapidly, the depth image-based haptic interaction is becoming viable for broadcasting applications. Since a real depth map usually contains discrete and rugged noise, its haptic interaction produces the distorted force feedback. To resolve these problems, we propose a two-step refinement and adaptive sampling algorithm. In the first step, noise is removed by the median-filtering technique in 2D image space. Since not all pixels can be used to reconstruct the 3D mesh due to limited system resources, the filtered map is adaptively sampled based on the depth variation. Sampled 2D pixels, called feature points, are triangulated and projected onto 3D space. In the second refinement step, we apply the Gaussian smoothing technique to the reconstructed 3D surface. Finally, 3D surfaces are rendered to compute a smooth depth map from Z-buffer.
The old hourse-bus terminals (1931)

The old hourse-bus terminals Get access Charles White Charles White Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume CLX, Issue feb07, 7 February 1931, Pages 102–103, https://doi.org/10.1093/nq/CLX.feb07.102h Published: 07 February 1931
Crystal structure of diamondlike carbon films prepared by ionized deposition from methane gas (1984)

Diamondlike carbon films have been prepared by ionized deposition from methane gas. The film structures were examined by transmission electron microscopy, electron diffraction, and electron spectroscopy for chemical analysis techniques. It was found that the structure of the carbon films could be classified into three types: (i) amorphous, (ii) graphite, and (iii) cubic. These types depended mainly on the deposition conditions. Usually crystalline carbon films were diamond mixed with graphite showing an average grain size of several hundred angstroms. Very hard films were composed of diamond crystallites distributed in amorphous matrix.
The<i>pst</i>Operon of<i>Bacillus subtilis</i>Is Specifically Induced by Alkali Stress (2003)

To cope with a sudden increase in the external pH value to 8.9, Bacillus subtilis cells induce about 80 genes which can be divided into two classes. Most of these genes are members of the sigma(W) regulon, while some are under the control of so-far-unknown transcriptional regulators. The genes of the pst operon belong to the second class. Here, we attempted to answer the questions of why and how the genes of this operon are induced. Using transcriptional fusions to two of the five genes of this operon, we confirmed their induction after alkali stress. Furthermore, a Northern blot experiment revealed that the complete operon was alkali inducible, that the transcriptional start site used was identical to that used after phosphate starvation, and that induction was prevented in a phoR background. Most interestingly, increasing the phosphate concentration within the medium prevented alkali induction of the pst operon, and phoA, another member of the PhoRP regulon, did not respond to alkali stress. In the end, we showed that alkali treatment completely prevented phosphate uptake. These results are discussed to explain alkali induction of the pst operon.
Second- and third-order dispersion compensation using a high resolution arrayed-waveguide grating (2002)

Second-order dispersion (6.0 ps/nm) is effectively controlled by time-space conversion using an arrayed-waveguide grating (AWG) and pulse compression by third-order dispersion compensation is successfully demonstrated.
Improvement of the user interface for video cassette recorders by 'memory-in-cassette' (1993)

It is shown that the user interface of a VCR can be much improved by providing a nonvolatile memory attached to the video cassette, which holds basic cassette and tape information as well as TOC (tables-of-contents) and UTOC (user TOC) data. The appropriate technology is EEPROM (electrically erasable programmable read-only memory) with serial interface as increasingly used for chip cards. The concept described provides the choice between a serial interface EEPROM for the standard cassette and a simple hard-wired PROM (programmable read-only memory) for low-cost products. The concept may be best applied to the next-generation VCR standard.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Einleitung (2002)

ZusammenfassungUnter elektromagnetischer Verträglichkeit (EMV, engl. EMC: electromagnetic compatibility) versteht man die Fähigkeit einer Anlage, eines Gerätes, einer Baugruppe oder Stufe, in der vorgesehenen oder vorgegebenen elektromagnetischen Umgebung definitionsgemäß zu arbeiten und dabei auch die Umgebung nicht unzulässig zu beeinflussen.
Novel sources of fungal cellulases for efficient deinking of composite paper waste (2008)

Twenty thermophilic/thermotolerant fungal strains were isolated from compositing soils and screened for production of different enzymes (Endoglucanases, β-glucosidase, Fpase and xylanases) to assess their deinking efficiency. Three isolates, Aspergillus sp. AMA, Aspergillus terreus AN1,and Myceliophthora fergusii T4I, identified on the basis of morphological and sequencing of amplified ITS1-5.8S-ITS2 rDNA region, showed significant deinking of composite waste paper (70% magazine and 30% Xerox copier/ laser print paper waste) as well as improved properties (brightness, tensile strength, tear index) of recycled paper sheets. The chosen strains Aspergillus sp. AMA, Aspergillus terreus AN1and Myceliophthora fergusii T4I, showed 53, 52.7, and 40.32% deinking with increase in brightness by 4.32, 3.56, and 3.01 % ISO, respectively. These cultures were found to produce multiple endoglucanases and were characterized to lack a cellulose binding module (CBD), which may be responsible for their better deinking efficiency.
Studies on Secotiaceous fungi IX the astrogastraceous series (1960)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Phenotypic effects of targeted mutations in the small subunit rRNA gene of Tetrahymena thermophila. (1993)

Tetrahymena thermophila is an ideal organism with which to study functional aspects of the rRNAs in vivo since the somatic rRNA genes of T. thermophila can be totally replaced by cloned copies introduced via microinjection. In this study, we made small insertions into seven sites within the small subunit rRNA gene and observed their phenotypic effects on transformed cells. Two mutated genes coding for rRNA (rDNAs), both of which bear insertions in highly conserved sequences, failed to transform and are therefore believed to produce nonfunctional rRNAs. Three other altered rDNAs produce functional rRNAs that can substitute for most or all of the cellular rRNA. Two of these bear insertions in highly variable regions, and, surprisingly, the other has an insertion in a region that is well conserved for both sequence and secondary structure among eucaryotes. In addition, two other insertions appear to destabilize rRNAs that contain them. Our findings make predictions concerning the positions of some of these sites within the tertiary structure of the small ribosomal subunit and thus serve as an in vivo test of the existing tertiary structure models for the small subunit rRNA. Our results are in good agreement with expectations based on sequence comparison and in vitro work.
Religious Orders Study and Rush Memory and Aging Project (2018)

Complexity at multiple levels needs to be understood and overcome to develop effective treatments and preventions for cognitive decline and AD dementia.
The muse object architecture (1991)

A next generation operating system should accommodate an ultra large-scale, open, self-advancing, and distributed environment. This environment is dynamic and versatile in nature. In it, an unlimited number of objects, ranging from fine to coarse-grained, are emerging, vanishing, evolving, and being replaced; computers of various processing capacities are dynamically connected and disconnected to networks; systems can optimize object execution by automatically detecting the user's and/or programmer's requirements. In this paper, we investigate several structuring concepts in existing operating systems. These structuring concepts include layered structuring, hierarchical structuring, policy/mechanism separation, collective kernel structuring, object-based structuring, open operating system structuring, virtual machine structuring, and proxy structuring.We adjudge that these structuring concepts are not sufficient to support the environment described above because they lack the abilities to handle dynamic system behavior and transparency and to control dependency. Thus, we propose a new operating system structuring concept which we call the Muse object architecture. In this architecture, an object is a single abstraction of a computing resource in the system. Each object has a group of meta-objects which provide an execution environment. These meta-objects constitute a meta-space which is represented within the meta-hierarchy. An object is causally connected with its meta-objects: the internal structure of an object is represented by meta-objects; an object can make a request of meta-computing; a meta-object can reflect the results of meta-computing to its object. We discuss object/meta-object separation, the meta-hierarchy, and reflective computing of the architecture. We then compare the Muse object architecture with the existing structuring concepts.We also demonstrate that the Muse object architecture is suitable for structuring future operating systems by presenting several system services of the Muse operating system such as class systems, a real-time scheduler with hierarchical policies, and free-grained objects management. Class systems facilitate programming by several classes of programming languages. A real-time scheduler with hierarchical policies can meet various types of real-time constraints presented by applications. Free-grained objects management can suit the object granularity to the application, so that an object is efficiently managed according to its granularity. Finally, we present the implementation of the Muse operating system which is designed based on the Muse object architecture. Version 0.3 of the Muse kernel is running on the MC68030 based Sony NEWS workstations.
Beckford in Hell: An Episode in the History of Secular Enchantment (2007)

In this essay, Simon During examines William Beckford's radical commitment to enchantment. Flirting with demonism, Beckford broke with conventional morality and absolved himself from participation in public life. He committed himself instead to an aestheticism dedicated both to the pursuit of private delight and to modes of self-undoing. This ethos was most intensely lived out at his coming-of-age party, for which he hired Philippe de Loutherbourg to produce special effects. The essay explores the historical underpinnings of Beckford's commitment to demonic enchantment and gestures at his role as a pioneer of modern culture. © 2007 by the Henry E. Huntington Library and Art Gallery.
High-Throughput Ester Hydrolysis with Catch-and-Release Isolation of Carboxylic Acids (2006)

ADVERTISEMENT RETURN TO ISSUEPREVReportNEXTHigh-Throughput Ester Hydrolysis with Catch-and-Release Isolation of Carboxylic AcidsTina M. MorwickView Author Information Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, Connecticut 06801-0368 Cite this: J. Comb. Chem. 2006, 8, 5, 649–651Publication Date (Web):August 22, 2006Publication History Received10 May 2006Published online22 August 2006Published inissue 1 September 2006https://pubs.acs.org/doi/10.1021/cc060064rhttps://doi.org/10.1021/cc060064rbrief-reportACS PublicationsCopyright © 2006 American Chemical SocietyRequest reuse permissionsArticle Views1674Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Alkyls,Hydrolysis,Organic compounds,Organic polymers,Solvents Get e-Alerts
Ecto‐nucleotide pyrophosphatase modulates the purinoceptor‐mediated signal transduction and is inhibited by purinoceptor antagonists (2000)

1. The effect of ecto-nucleotide pyrophosphatase (ecto-NPPase; EC 3.6.1. 9) on the ATP- and ADP-mediated receptor activation was studied in rat C6 glioma cells. The P2-purinoceptor antagonists pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid (PPADS) and reactive blue (RB2) are potent inhibitors (IC(50)=12+/-3 microM) of the latter enzyme. 4,4'-diisothiocyanatostilbene-2,2' disulfonic acid (DIDS), 5'-phosphoadenosine 3'-phosphate (PAP) and suramin were less potent inhibitors with an IC(50) of 22+/-4, 36+/-7 and 72+/-11 microM respectively. 2. P1-purinoceptor antagonists CGS 15943, cyclo-pentyl theophylline (CTP) and theophylline did not affect the activity of the ecto-NPPase. 3. ATP- and ADP-mediated P2Y(1)-like receptor activation inhibited the (-)-isoproterenol-induced increase of intracellular cyclic AMP concentration. PPADS, an ineffective P2Y-antagonist in C6, potentiated the ATP and ADP effect approximately 3 fold due to inhibition of nucleotide hydrolysis by the ecto-NPPase. 4. We conclude that ecto-NPPase has a modulator effect on purinoceptor-mediated signalling in C6 glioma cell cultures.
Caveolin versus Calmodulin (1997)

Nitric oxide is synthesized in diverse mammalian tissues by a family of calmodulin-dependent nitric oxide synthases. The endothelial isoform of nitric oxide synthase (eNOS) is targeted to the specialized signal-transducing membrane domains termed plasmalemmal caveolae. Caveolin, the principal structural protein in caveolae, interacts with eNOS and leads to enzyme inhibition in a reversible process modulated by Ca2+-calmodulin (Michel, J. B., Feron, O., Sacks, D., and Michel, T. (1997) J. Biol. Chem. 272, 15583-15586). Caveolin also interacts with other structurally distinct signaling proteins via a specific region identified within the caveolin sequence (amino acids 82-101) that appears to subserve the role of a "scaffolding domain." We now report that the co-immunoprecipitation of eNOS with caveolin is completely and specifically blocked by an oligopeptide corresponding to the caveolin scaffolding domain. Peptides corresponding to this domain markedly inhibit nitric oxide synthase activity in endothelial membranes and interact directly with the enzyme to inhibit activity of purified recombinant eNOS expressed in Escherichia coli. The inhibition of purified eNOS by the caveolin scaffolding domain peptide is competitive and completely reversed by Ca2+-calmodulin. These studies establish that caveolin, via its scaffolding domain, directly forms an inhibitory complex with eNOS and suggest that caveolin inhibits eNOS by abrogating the enzyme's activation by calmodulin.
Toolkit to support intelligibility in context-aware applications (2010)

Context-aware applications should be intelligible so users can better understand how they work and improve their trust in them. However, providing intelligibility is non-trivial and requires the developer to understand how to generate explanations from application decision models. Furthermore, users need different types of explanations and this complicates the implementation of intelligibility. We have developed the Intelligibility Toolkit that makes it easy for application developers to obtain eight types of explanations from the most popular decision models of context-aware applications. We describe its extensible architecture, and the explanation generation algorithms we developed. We validate the usefulness of the toolkit with three canonical applications that use the toolkit to generate explanations for end-users.
Infrared Spectroscopy of Competitive Interactions between Liquid Crystals, Metal Salts, and Dimethyl Methylphosphonate at Surfaces (2006)

We report the use of Fourier transform polarization modulation infrared reflection-absorption spectroscopy (PM-IRRAS) to characterize the influence of dimethyl methylphosphonate (DMMP) on the molecular interactions occurring within thin films of nitrile-containing liquid crystals supported on surfaces presenting metal perchlorate salts. Infrared spectra obtained using thin films of 4'-octyl-4-biphenylcarbonitrile (8CB) supported on copper(II) perchlorate salts reveal the nitrile groups of 8CB to be coordinated to the copper(II) on these surfaces, and subsequent exposure of the system to DMMP to result in the elimination of these coordinated nitrile groups. Concurrently, evidence of coordination of the phosphoryl group of DMMP with copper(II) is provided by measurement of a shift of the phosphoryl stretch from 1246 to 1198 cm(-1). In contrast, surfaces presenting nickel(II) perchlorate salts only weakly coordinate with DMMP [the phosphoryl peak shifts from 1246 to 1213 cm(-1) in the presence of nickel(II)], and exposure of 8CB to DMMP results in only partial loss of coordination of the nitrile groups of 8CB with nickel(II). These PM-IRRAS measurements and others reported in this article provide insights into the molecular origins of macroscopic ordering transitions that are observed when micrometer-thick films of nitrile-containing liquid crystals supported on copper(II) or nickel(II) perchlorate are exposed to DMMP: Upon exposure to DMMP, nematic phases of 4'-pentyl-4-biphenylcarbonitrile (5CB) supported on copper(II) perchlorate salts undergo ordering transitions, whereas 5CB supported on nickel(II) perchlorate salts do not. Our IR results support the hypothesis that these ordering transitions reflect the relative strengths of coordination interactions occurring between the 5CB, DMMP, and the metal salts at these interfaces.
High performance damascene gate CMOSFETs with recessed channel formed by plasma oxidation and etching method (RC-POEM) (2003)

We report on high performance transistors using a new recessed channel formed by plasma oxidation and etching method (RC-POEM). The advantages of RC-POEM are: [a] lowering source/drain extension sheet resistance while suppressing lateral diffusion of extension region; [b] forming pseudo-raised extension using only plasma oxidation and wet etching. RC-POEM suppressed short channel effects down to 35nm physical gate length and high drive current were obtained.