gebhart/patrepeval huggingface dataset:
NOMENCLATURE (1956)

RETURN TO ISSUEPREVNewsNEXTNOMENCLATUREAUSTIN M. PATTERSONCite this: Chem. Eng. News 1956, 34, 10, 1075Publication Date (Print):March 5, 1956Publication History Published online5 November 2010Published inissue 5 March 1956https://pubs.acs.org/doi/10.1021/cen-v034n010.p1075ahttps://doi.org/10.1021/cen-v034n010.p1075anewsACS PublicationsCopyright © 1956 AMERICAN CHEMICAL SOCIETYArticle Views6Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Inorganic compounds Get e-Alerts
La lámpara maravillosa, de Valle-Inclán y la invención continua como una constante estética (1986)

Sin duda Valle-Incln se refera a esta transformacin cuando en 1924 escribi a C. Rivas Cherif que Tirano Banderas -
Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation (2005)

Angiopoietin (Ang) signaling plays a role in angiogenesis and remodeling of blood vessels through the receptor tyrosine kinase Tie2, which is expressed on blood vessel endothelial cells (BECs). Recently it has been shown that Ang-2 is crucial for the formation of lymphatic vasculature and that defects in lymphangiogenesis seen in Ang-2 mutant mice are rescued by Ang-1. These findings suggest important roles for Ang signaling in the lymphatic vessel system; however, Ang function in lymphangiogenesis has not been characterized. In this study, we reveal that lymphatic vascular endothelial hyaluronan receptor 1-positive (LYVE-1(+)) lymphatic endothelial cells (LECs) express Tie2 in both embryonic and adult settings, indicating that Ang signaling occurs in lymphatic vessels. Therefore, we examined whether Ang-1 acts on in vivo lymphatic angiogenesis and in vitro growth of LECs. A chimeric form of Ang-1, cartilage oligomeric matrix protein (COMP)-Ang-1, promotes in vivo lymphatic angiogenesis in mouse cornea. Moreover, we found that COMP-Ang-1 stimulates in vitro colony formation of LECs. These Ang-1-induced in vivo and in vitro effects on LECs were suppressed by soluble Tie2-Fc fusion protein, which acts as an inhibitor by sequestering Ang-1. On the basis of these observations, we propose that Ang signaling regulates lymphatic vessel formation through Tie2.
<i>Klebsiella pneumoniae</i>Antimicrobial Drug Resistance, United States, 1998–2010 (2012)

We studied antimicrobial-resistant Klebsiella pneumoniae for 1998-2010 by using data from The Surveillance Network. Susceptibility results (n = 3,132,354) demonstrated significant increases in resistance to all antimicrobial drugs studied, except tetracycline. Cross-resistance among carbapenem-resistant K. pneumoniae was lower for tetracycline and amikacin.
Motion compensated video compression using adaptive transformations (2002)

Block-based motion compensation fails to maintain an acceptable level of prediction error which makes the transmission of this error impossible for very low bit-rate coding owing to the small bit allocation. The reason is that the motion model assumed in block-based techniques cannot approximate the motion in the real world precisely. To develop an effective motion compensation method for very low bit-rate video coding, we address the issue of adopting more sophisticated motion model than block-based. The motion model discussed here is based on the representation of optical flow in its principal components domain. The performance of motion compensation based on this model is compared with MPEG using the PSNR measure and qualitative experiments. Both of these criterias show a gain of compression in the order of 30%.
Measuring Selective Estrogen Receptor Modulator (SERM)–Membrane Interactions with Second Harmonic Generation (2014)

The interaction of selective estrogen receptor modulators (SERMs) with lipid membranes has been measured at clinically relevant serum concentrations using the label-free technique of second harmonic generation (SHG). The SERMs investigated in this study include raloxifene, tamoxifen, and the tamoxifen metabolites 4-hydroxytamoxifen, N-desmethyltamoxifen, and endoxifen. Equilibrium association constants (Ka) were measured for SERMs using varying lipid compositions to examine how lipid phase, packing density, and cholesterol content impact SERM-membrane interactions. Membrane-binding properties of tamoxifen and its metabolites were compared on the basis of hydroxyl group substitution and amine ionization to elucidate how the degree of drug ionization impacts membrane partitioning. SERM-membrane interactions were probed under multiple pH conditions, and drug adsorption was observed to vary with the concentration of soluble neutral species. The agreement between Ka values derived from SHG measurements of the interactions between SERMs and artificial cell membranes and independent observations of the SERMs efficacy from clinical studies suggests that quantifying membrane adsorption properties may be important for understanding SERM action in vivo.
A<i>Vibrio cholerae</i>ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin (2008)

The Vibrio cholerae ghost (rVCG) platform is an effective carrier and delivery system for designing efficacious Chlamydia vaccines. We investigated whether CTA2B, the nontoxic derivative of cholera toxin, can augment protective immunity conferred by an rVCG-based chlamydial vaccine and enhance cross-protection against heterologous chlamydial strains. An rVCG vaccine coexpressing chlamydial major outer membrane protein and CTA2B was genetically constructed and antigens were targeted to the inner membrane of V. cholerae before ghost production by gene E-mediated lysis. Effective immunomodulation by CTA2B was demonstrated by the ability of the vaccine construct to enhance the activation and maturation of dendritic cells in vitro. Also, C57BL/6 mice immunized via mucosal and systemic routes showed increased specific mucosal and systemic antibody and T-helper type-1 (Th1) responses, irrespective of the route. The enhanced production of IFN-gamma, but not IL-4 by genital mucosal and splenic T cells, indicated a predominantly Th1 response. Clearance of the Chlamydia muridarum vaginal infection was significantly enhanced by codelivery of the vaccine with CTA2B, with the intravaginal route showing a moderate advantage. These results indicate that the rVCG-based vaccine is capable of inducing cross-protection against heterologous chlamydial serovars and that incorporation of mucosal adjuvants, such as CTA2B in the rVCG delivery platform, may enhance protective immunity.
Parallel LDPC Decoder for CMMB on CPU and GPU Using OpenCL (2016)

Recently, Open Computing Language (OpenCL) has been proposed to provide a framework that supports heterogeneous computing platforms. By using an OpenCL framework, digital communication systems can support various protocols in a unified computing environment to achieve both high portability and high performance. This article introduces a parallel software decoder of Low Density Parity Check (LDPC) codes for China Multimedia Mobile Broadcasting (CMMB) on a heterogeneous platform. Each step of LDPC decoding has different parallelization characteristics. In this paper, steps suitable for task-level parallelization are executed on the CPU, and steps suitable for data-level parallelization are processed by the GPU. To improve the performance of the proposed OpenCL kernels for LDPC decoding operations, explicit thread scheduling, loop-unrolling, and effective data transfer techniques are applied. The proposed LDPC decoder achieves high performance by using heterogeneous multi-core processors on a unified computing framework.
Suppression of Frequently Recurring Genital Herpes (1984)

We studied 35 otherwise healthy adults with frequently recurring genital herpes (greater than or equal to 1 episode per month), in a double-blind trial comparing oral acyclovir with placebo capsules for suppression of recurrent infection. The patients were treated for 125 days unless herpes recurred. Among 32 evaluable patients, there were significantly fewer recurrences during acyclovir treatment (4 of 16) than during placebo treatment (16 of 16, P less than 0.001). The mean duration of therapy was significantly longer for patients receiving acyclovir than for those receiving placebo (114.9 vs. 24.8 days, P less than 0.001). Of 19 patients who had recurrences in the blind trial, only 2 had recurrences when given acyclovir in a second, open-study phase. All patients had recurrences after completing acyclovir treatment. The therapy was well tolerated, with minimal gastrointestinal upset and one hypersensitivity reaction. Studies of the viral isolates demonstrated that lesions developing in patients receiving acyclovir contained drug-resistant virus. Later recurrences in these patients were associated with drug-sensitive virus. We conclude that oral acyclovir suppresses genital herpes in patients with frequent recurrences, but the potential for problems with drug resistance and the long-term safety need to be more fully explored.
Photoluminescence on high-quality Al<i>x</i>Ga1−<i>x</i>As grown by metalorganic vapor-phase epitaxy using alane bis(dimethylethylamine) (1992)

Photoluminescence (PL) spectra are reported of initial results of AlxGa1−xAs grown by metalorganic vapor-phase epitaxy (MOVPE), using a new precursor, alane bis(dimethylethylamine), as the aluminum source. The advantage of this new precursor over other alane precursors used previously is that it is liquid at room temperature. Using this new precursor instead of trimethylaluminum (TMAl), we found a reduction by a factor 6 in carbon incorporation when it was used together with trimethylgallium (TMGa), whereas a reduction by a factor 50 was found when it was used in combination with triethylgallium (TEGa). At low excitation density the linewidth of the separate donor bound exciton (D0,X) was 2.6 meV at an Al fraction of 0.31. This is comparable with the smallest values ever reported in literature for MOVPE-grown AlxGa1−xAs with an Al fraction higher than 20%. This narrow linewidth indicates a very uniform aluminum composition.
Application of Supercritical Fluid Extraction to Components of Crude Drugs and Plants. III. Extraction of Pigments from Lithospermum Root and Licorice Root (1987)

Supercritical fluid extraction was applied to the pigments of Lithospermum root and those of licorice root. Shikonin derivatives, the red pigments of Lithospermum root, were effectively extracted with supercritical carbon dioxide without using entrainer. Application of entrainer (ethanol or water) reduced efficiency in this extraction. The amounts of the substances which are immobile on TLC and regarded as oxidized products of shikonin derivatives, were significantly smaller than that obtained by the ordinary extraction with organic solvent (ether) when extracted with supercritical fluid without using entrainer, indicating an advantage of the latter extraction. Liquiritigenin of Sipei licorice (licorice root from the nor thwest region of China) and Tongpei licorice (licorice root from the northeast region of China), was extracted with supercritical carbon dioxide in the presence of the entrainer (5% ethanol). However, isoliquiritigenin possessing three phenolic hydroxyl groups was not extracted with supercritical fluid with or without entrainers (water and ethanol). Licochalcone A was extracted from Sinkiang licorice (licorice root from Sinkiang region of China), with carbon dioxide only, but the extraction of licochalcone B required addition of ethanol as entrainer.
The regulatory 1α subunit of protein kinase A modulates renal cystogenesis (2017)

The failure of the polycystins (PCs) to function in primary cilia is thought to be responsible for autosomal dominant polycystic kidney disease (ADPKD). Primary cilia integrate multiple cellular signaling pathways, including calcium, cAMP, Wnt, and Hedgehog, which control cell proliferation and differentiation. It has been proposed that mutated PCs result in reduced intracellular calcium, which in turn upregulates cAMP, protein kinase A (PKA) signaling, and subsequently other proliferative signaling pathways. However, the role of PKA in ADPKD has not been directly ascertained in vivo, although the expression of the main regulatory subunit of PKA in cilia and other compartments (PKA-RIα, encoded by <i>PRKAR1A</i>) is increased in a mouse model orthologous to ADPKD. Therefore, we generated a kidney-specific knockout of <i>Prkar1a</i> to examine the consequences of constitutive upregulation of PKA on wild-type and <i>Pkd1</i> hypomorphic (<i>Pkd1</i><sup>RC</sup>) backgrounds. Kidney-specific loss of <i>Prkar1a</i> induced renal cystic disease and markedly aggravated cystogenesis in the <i>Pkd1</i><sup>RC</sup> models. In both settings, it was accompanied by upregulation of Src, Ras, MAPK/ERK, mTOR, CREB, STAT3, Pax2 and Wnt signaling. On the other hand, Gli3 repressor activity was enhanced, possibly contributing to hydronephrosis and impaired glomerulogenesis in some animals. To assess the relevance of these observations in humans we looked for and found evidence for kidney and liver cystic phenotypes in the Carney complex, a tumoral syndrome caused by mutations in <i>PRKAR1A</i> These observations expand our understanding of the pathogenesis of ADPKD and demonstrate the importance of <i>PRKAR1A</i> highlighting PKA as a therapeutic target in ADPKD.
64Cu-DOTA-Anti-CTLA-4 mAb Enabled PET Visualization of CTLA-4 on the T-Cell Infiltrating Tumor Tissues (2014)

Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) targeted therapy by anti-CTLA-4 monoclonal antibody (mAb) is highly effective in cancer patients. However, it is extremely expensive and potentially produces autoimmune-related adverse effects. Therefore, the development of a method to evaluate CTLA-4 expression prior to CTLA-4-targeted therapy is expected to open doors to evidence-based and cost-efficient medical care and to avoid adverse effects brought about by ineffective therapy. In this study, we aimed to develop a molecular imaging probe for CTLA-4 visualization in tumor. First, we examined CTLA-4 expression in normal colon tissues, cultured CT26 cells, and CT26 tumor tissues from tumor-bearing BALB/c mice and BALB/c nude mice by reverse transcription polymerase chain reaction (RT-PCR) analysis and confirmed whether CTLA-4 is strongly expressed in CT26 tumor tissues. Second, we newly synthesized 64Cu-1,4,7,10-tetraazacyclododecane-N,N',N″,N‴-tetraacetic acid-anti-mouse CTLA-4 mAb (64Cu-DOTA-anti-CTLA-4 mAb) and evaluated its usefulness in positron emission tomography (PET) and ex-vivo biodistribution analysis in CT26-bearing BALB/c mice. High CTLA-4 expression was confirmed in the CT26 tumor tissues of tumor-bearing BALB/c mice. However, CTLA-4 expression was extremely low in the cultured CT26 cells and the CT26 tumor tissues of tumor-bearing BALB/c nude mice. The results suggested that T cells were responsible for the high CTLA-4 expression. Furthermore, 64Cu-DOTA-anti-CTLA-4 mAb displayed significantly high accumulation in the CT26 tumor, thereby realizing non-invasive CTLA-4 visualization in the tumor. Together, the results indicate that 64Cu-DOTA-anti-CTLA-4 mAb would be useful for the evaluation of CTLA-4 expression in tumor.
Nasopharyngeal Pushback in Treatment of Velopharyngeal Insufficiency (1976)

We describe a new technique for extensive retropositioning of the soft palate for the treatment of velopharyngeal insufficiency. This technique is identified as a nasopharyngeal pushback, and has been used repeatedly in conjunction with both a Cronin nasal flap and a superiorly based pharyngeal flap when maximum retropositioning was needed. This procedure has been used for over ten years, each time obtaining an additional pushback distance equal to or greater than the distance achieved by freeling the soft palate from the posterior border of the hard palate.
BIOLOGICAL AND PHARMACOLOGICAL PROPERTIES OF TERMINALIA CHEBULA RETZ. (HARITAKI)- AN OVERVIEW (2012)

ABSTRACTMedicinal plants have been considered valuable and cheap source of unique phytoconstituents which are used extensively in the development of drugs against various diseases. A large proportion of the world population, especially in the developing countries relies mainly on the traditional system of medicine. The use of plants and plant products in medicines is getting popularized because the herbal medicines are cheap and havenatural origin with higher safety margins and lesser or no side effects. Terminalia chebula Retz. (T. chebula) belongs to the family Combretaceae and is one of the most important medicinal plants used in medicines of ayurveda, siddha, unani and homeopathy. It is called the “King of Medicines” in Tibet and is listed first in the Ayurvedic material medica because of its extraordinary power of wound healing and a wide spectrum of medicinal properties. T. chebula possesses antibacterial, antifungal, antiviral, antidiabetic, antimutagenic, antioxidant, antiulcer and wound healing properties. It also prevents cardiac damage and is used for the treatment of kidney disease. It is a mild, safe and effective laxative in traditional medicine. T. chebula and its phytoconstituents have therapeutic effect with no toxicity. T. chebula is an active ingredient of the well known herbal prepara
.alpha.-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines (1983)

A series of 2-(aminomethyl)imidazolines related to the alpha-adrenergic antagonist phentolamine was prepared and evaluated for alpha-adrenergic agonist and antagonist activities in the isolated, field-stimulated rat vas deferens. Affinities for alpha-adrenergic receptors were determined by displacement of [3H]clonidine and [3H]prazosin from membrane binding sites of calf cerebral cortex. This series provided a variety of alpha-adrenergic profiles, with some of the (aminomethyl)imidazolines being nonselective alpha 1- and alpha 2-adrenergic antagonists like phentolamine, while others were either nonselective alpha 1- and alpha 2-agonists or mixed alpha 1-agonists/alpha 2-antagonists.
Enhanced pathogenicity of chicken anemia agent by infectious bursal disease virus relating to the occurrence of Marek's disease vaccination breaks. (1989)

[in Japanese]
Intraplatelet Serotonin, β-Thromboglobulin, and Histamine Concentrations and Thromboxane A2 Synthesis in Renal Disease (1991)

Intraplatelet serotonin (5-HT), beta-thromboglobulin (beta-TG), and histamine content as well as platelet total thromboxane A2 (TXA2) synthesizing capacity were measured in 53 patients with chronic renal disease: nephrotic syndrome (n = 18); end-stage renal failure (ESRF; n = 13); continuous ambulatory peritoneal dialysis (CAPD; n = 9); hemodialysis (HD; n = 13). These indices of platelet function were correlated with plasma total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) concentrations. When compared with controls, intraplatelet 5-HT was significantly reduced in all patient groups studied and beta-TG was diminished in all patient groups except CAPD. Total platelet TXA2 synthesizing capacity was increased in ESRF and HD groups. Intraplatelet histamine content was not altered in any of the patient groups studied. There was a significant inverse correlation between intraplatelet 5-HT content on the one hand and plasma TC, LDL-C, and TG on the other. The depletion of intraplatelet 5-HT and beta-TG and the increase in total TXA2 synthesizing capacity are consistent with platelet activation in chronic renal disease. The correlation between these indices of platelet activation and TC, LDL-C, HDL-C, and TG suggests that changes in the concentrations of these lipids may contribute to the activation of platelets in these conditions.
Crystallinity in perfluorosulfonic acid ionomers and related polymers (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystallinity in perfluorosulfonic acid ionomers and related polymersHoward W. Starkweather Jr.Cite this: Macromolecules 1982, 15, 2, 320–323Publication Date (Print):March 1, 1982Publication History Published online1 May 2002Published inissue 1 March 1982https://pubs.acs.org/doi/10.1021/ma00230a023https://doi.org/10.1021/ma00230a023research-articleACS PublicationsRequest reuse permissionsArticle Views813Altmetric-Citations143LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Protective Effect of Ethanolic Extract of Seeds of<i>Moringa oleifera</i>Lam. Against Inflammation Associated with Development of Arthritis in Rats (2007)

The present investigation was carried out to study the anti-arthritic activity of ethanolic extract of seeds of Moringa oleifera Lam. (MOEE) in adjuvant-induced arthritis in adult female Wistar rats. During the experimental period, body weight, paw edema volume (primary lesion) and arthritic index (secondary lesion) was observed. On the 21st day, serum from each animal was used for estimation of Rheumatoid Factor (RF) value and levels of selected cytokines (TNFalpha, IL-1, and IL-6). Whole blood was used for measurement of erythrocyte sedimentation rate (ESR). Liver homogenate was utilized for assessment of oxidative stress and histopathology was performed to measure degree of inflammation in synovial joint. Our results suggest that, percentage reduction in body weight was less, paw edema volume and arthritic index score was decreased significantly as compared to diseased control animals. Serum levels of RF, TNF-alpha, IL-1, and IL-6 also showed decreased levels as compared to those in the diseased control group. Treatment with MOEE also altered oxidative stress in relation to its anti-inflammatory activity. Histopathological observations showed mild or less infiltration of lymphocytes, angiogenesis and synovial lining thickening. From all above results and observations, it can be concluded that Moringa oleifera possesses promising antiarthritic property.