gebhart/patrepeval huggingface dataset:
The use of luminescence spectroscopy in aiding the identification of commercial polymers (1976)

The fluorescence and phosphorescence properties of a range of commercial polymers have been examined. Each polymer tested exhibited characteristic excitation and emission spectra. Phosphorescence lifetimes were also found to vary significantly. The spectral data obtained are discussed with a view to applying luminescence techniques as a rapid non-destructive method for the characterisation of commercial polymers.
Isolating gene-corrected stem cells without drug selection (2005)

Progress in isolating stem cells from tissues, or generating them from adult cells by nuclear transfer, encourages attempts to use stem cells from affected individuals for gene correction and autologous therapy. Current viral vectors are efficient at introducing transgenic sequences but result in random integrations. Gene targeting, in contrast, can directly correct an affected gene, or incorporate corrective sequences into a site free from undesirable side effects, but efficiency is low. Most current targeting procedures, consequently, use positive-negative selection with drugs, often requiring >/=10 days. This drug selection causes problems with stem cells that differentiate in this time or require feeder cells, because the feeders must be drug resistant and so are not eliminated by the selection. To overcome these problems, we have developed a procedure for isolating gene-corrected stem cells free from feeder cells after 3-5 days culture without drugs. The method is still positive-negative, but the positive and negative drug-resistance genes are replaced with differently colored fluorescence genes. Gene-corrected cells are isolated by FACS. We tested the method with mouse ES cells having a mutant hypoxanthine phosphoribosyltransferase (Hprt) gene and grown on feeder cells. After 5 days in culture, gene-corrected cells were obtained free from feeder cells at a "purity" of >30%, enriched >2,000-fold and with a recovery of approximately 20%. Corrected cells were also isolated singly for clonal expansion. Our FACS-based procedure should be applicable at small or large scale to stem cells that can be cultured (with feeder cells, if necessary) for >/=3 days.
Cyclopropane Derivatives. I. Studies of the Photochemical and Thermal Chlorination of Cyclopropane (1945)

Gustavson has reported that the photochemical chlorination of cyclopropane gave 1, 1-dichlorocyclopropane and high-boiling compounds resulting from ring-opening reactions as the principal products. Small quantities of cyclopropyl chloride were isolated but the yields were unsatisfactory and attempts were made to prepare the monohalide by other methods. In beginning an investigation of the chemistry of cyclopropyl halides, we have studied the photochemical and thermal chlorination of cyclopropane in flow systems using conditions which were hoped to give useful yields of cyclopropyl chloride.
Probe-Aided MulTCP (2008)

An aggregate congestion control mechanism, namely Probe-Aided MulTCP (PA-MulTCP), is proposed in this paper. It is based on MulTCP,a proposal for enabling an aggregate to emulate the behavior of multiple concurrent TCP connections. The objective of PA-MulTCP is to ensure the fair sharing of the bottleneck bandwidth between the aggregate and other TCP or TCP-friendly flows while keeping lightweightness and responsiveness. Unlike MulTCP, there are two congestion window loops in PA-MulTCP, namely the probe window loop and the adjusting window loop.The probe window loop constantly probes the congestion situation and the adjusting window loop dynamically adjusts the congestion window size for the arriving and departing flows within the aggregate Our simulations demonstrate that PA-MulTCP is more stable and fairer than MulTCP over a wide range of the weight N in steady conditions as well as in varying congestion conditions. PA-MulTCP is also responsive to flow arrival/departure and thus reduces the latency of short-lived transfers. Furthermore, PA-MulTCP is lightweight, since it enjoys above advantages at the cost of only an extra probe window loop, which has a marginal influence on the implementation complexity. Finally, the design of PA-MulTCP decouples the congestion management from the other functionalities in the aggregate flow management. As a result, PA-MulTCP could be potentially applied to a wider range of scenarios, e.g. wireless TCP proxies, edge-to-edge overlays, QoS provisioning and mass data transport. TCP, Fairness, Congestion Control, Aggregate Flow Management
Converging Flow of Polymer Melts (1981)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation D. C. Huang, R. N. Shroff; Converging Flow of Polymer Melts. J. Rheol. 1 December 1981; 25 (6): 605–617. https://doi.org/10.1122/1.549651 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe Society of RheologyJournal of Rheology Search Advanced Search |Citation Search
Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent <i>Clostridium difficile</i> Infection (2016)

clinicaltrials.gov Identifier:NCT01398969.
Full-color holographic projection display system featuring an achromatic Fourier filter (2017)

We propose a full-color complex holographic display system design comprised of three R/G/B amplitude-only spatial light modulators and an achromatic Fourier filter. A key feature of the design is a single achromatic Fourier bandpass filter for robust axial R/G/B color matching, whereby the R/G/B holographic image light fields can be three-dimensionally aligned. The synthesis algorithm producing the full-color computer-generated holograms for this system is described and a full-color optical reconstruction of the designed holographic three-dimensional images is experimentally demonstrated.
White Matter Changes in Elderly People: MR-pathologic Correlations (2006)

Magnetic resonance (MR) imaging features of white matter lesions, often seen in the elderly, are correlated with histologic findings. Dilatation of perivascular spaces is seen, especially in the frontal and/or parietal subcortical white matter; the spaces are less than 3 mm in diameter and have sharp margins with no perifocal abnormality. Old lacunar infarcts are larger than 3 mm in diameter and are irregularly shaped and accompanied by perifocal myelin pallor and gliosis. Periventricular hyperintensity, including cap and rim, histologically shows myelin pallor, dilatation of perivascular spaces, discontinuity of the ependymal lining, and subependymal gliosis. Deep and subcortical white matter hyperintensity reflects myelin pallor and dilatation of perivascular spaces. Diffuse white matter lesion, seen in Binswanger's disease, shows myelin pallor and tissue rarefaction associated with loss of myelin and axons. U-fibers are usually well preserved. Severe arteriosclerosis and arteriolosclerosis are usually seen in the white matter. Knowledge of the pathologic features of incidental changes in white matter helps in understanding MR imaging findings.
Interaction of drugs, hormones, and nutrition in the causes of cancer (1979)

Hormones may act as promoters in the carcinogenic process, and occasionally their metabolites may act as antihormones or have new physiologic effects. Drugs can interact with the endocrine system in many ways. They can promote secretion of a hormone, alter its rate of removal from plasma, change plasma protein-binding characteristics, or modify routes of metabolism. Estrogens have a preparative effect on the uterine endometrium. There are biologic, clinical and epidemiologic reasons for believing that estrogen administration to postmenopausal women increases the risk for endometrial cancer. Although there are similar biologic reasons to associate prolonged estrogenic stimulation with breast cancerr, evidence for such an association is weak. Oral contraceptive use has been associated with a variety of hepatocellular tumors. Although estrogens, per se, can effect several hepatic functions, it seems likely that the 17 alpha-alkyl and 17 alpha-ethinyl functions of the progestins and estrogens are involved in this process. The role of estrogen use during pregnancy in the causation of vaginal cancer in female offspring and the role of androgens in prostate cancer have been discussed.
Removable Polyurethane Encapsulants (1977)

Two castable thermoplastic polyurethane formulations have been developed for use as removable electronics packaging materials. The first formulation would be employed in situations where some elastomeric properties are desired. Mechanical properties for this formulation are: tensile strength 1675 psi, elongation 480%, and modulus 2.2 X 10 4 psi. The second formulation more closely simulates an epoxy resin and the mechanical properties are: tensile strength 6040 psi, elongation 6.5%, and modulus 2.8 X 10 5 psi. Both casting resins can be filled (e.g., with Al 2 O 3 ) which reduces the coefficient of thermal expansion (~ 80 X 10 -6 to ~ 40 X 10 -6 /°C) and susceptibility to creep. The two formulations are soluble in polar organic solvents such as dimethylformamide and tetrahydrofuran. Both formulations were synthesized in bulk and based on reaction rate studies, they exhibit a diffusion controlled process in the latter stages of reaction.
Phospholipase C-γ1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP (2009)

High NaCl elevates activity of the osmoprotective transcription factor TonEBP/OREBP by increasing its phosphorylation, transactivating activity, and localization to the nucleus. We investigated the possible role in this activation of phospholipase C-gamma1 (PLC-gamma1), which has a predicted binding site at TonEBP/OREBP-phospho-Y143. We find the following. (i) Activation of TonEBP/OREBP transcriptional activity by high NaCl is reduced in PLC-gamma1 null cells and in HEK293 cells in which PLC-gamma1 is knocked down by a specific siRNA. (ii) High NaCl increases phosphorylation of TonEBP/OREBP at Y143. (iii) Wild-type PLC-gamma1 coimmunoprecipitates with wild-type TonEBP/OREBP but not TonEBP/OREBP-Y143A, and the coimmunoprecipitation is increased by high NaCl. (iv) PLC-gamma1 is part of the protein complex that associates with TonEBP/OREBP at its DNA binding site. (v) Knockdown of PLC-gamma1 or overexpression of a PLC-gamma1-SH3 deletion mutant reduces high NaCl-dependent TonEBP/OREBP transactivating activity. (vi) Nuclear localization of PLC-gamma1 is increased by high NaCl. (vii) High NaCl-induced nuclear localization of TonEBP/OREBP is reduced if cells lack PLC-gamma1, if PLC-gamma1 mutated in its SH2C domain is overexpressed, or if Y143 in TonEBP/OREBP is mutated to alanine. (viii) Expression of recombinant PLC-gamma1 restores nuclear localization of wild-type TonEBP/OREBP in PLC-gamma1 null cells but not of TonEBP/OREBP-Y143A. (ix) The PLC-gamma1 phospholipase inhibitor U72133 inhibits nuclear localization of TonEBP/OREBP but not the increase of its transactivating activity. We conclude that, when NaCl is elevated, TonEBP/OREBP becomes phosphorylated at Y143, resulting in binding of PLC-gamma1 to that site, which contributes to TonEBP/OREBP transcriptional activity, transactivating activity, and nuclear localization.
Cyanocobalamin — A Case for Withdrawal: Discussion Paper (1992)

Keywords anaemia, pernicious, optic neuropathies, chronic cyanide intoxication, hydroxocobalamin, cyanocobalamin
Ultra selective 22-pole, 10-transmission zero superconducting bandpass filter surpasses 50-pole Chebyshev rejection (2003)

An ultra selective filter for 3G and 4G wireless application is presented. The demonstrated filter consists of twenty-two resonators and five cross couplings that produce ten transmission-zeros. The filter was designed at 1950 MHz center frequency with a 20 MHz bandwidth to meet existing 3G wireless applications. The measured data from the filter exhibited excellent selectivity, steeper than 30 dB/100 kHz skirt slope and 90 dB rejection at 350 kHz from the band edge. This filter surpasses the rejection of a 50-pole Chebyshev filter. To design a large number of resonators in a limited wafer area, a new compact resonator was developed. The filter was fabricated using a YBCO thin film on a 2-inch MgO wafer.
Hardware support for dynamic activation of compiler-directed computation reuse (2000)

Compiler-directed Computation Reuse (CCR) enhances program execution speed and efficiency by eliminating dynamic computation redundancy. In this approach, the compiler designates large program regions for potential reuse. During run time, the execution results of these reusable regions are recorded into hardware buffers for future reuse. Previous work shows that CCR can result in significant performance enhancements in general applications. A major limitation of the work is that the compiler relies on value profiling to identify reusable regions, making it difficult to deploy the scheme in many software production environments. This paper presents a new hardware model that alleviates the need for value profiling at compile time. The compiler is allowed to designate reusable regions that may prove to be inappropriate. The hardware mechanism monitors the dynamic behavior of compiler-designated regions and selectively activates the profitable ones at run time. Experimental results show that the proposed design makes more effective utilization of hardware buffer resources, achieves rapid employment of computation regions, and improves reuse accuracy, all of which promote more flexible compiler methods of identifying reusable computation regions.
Current status of lupus genetics (2007)

Over the past 40 years more than 100 genetic risk factors have been defined in systemic lupus erythematosus through a combination of case studies, linkage analyses of multiplex families, and case-control analyses of single genes. Multiple investigators have examined patient cohorts gathered from around the world, and although we doubt that all of the reported associations will be replicated, we have probably already discovered many of the genes that are important in lupus pathogenesis, including those encoding human leukocyte antigen-DR, Fcgamma receptor 3A, protein tyrosine phosphatase nonreceptor 22, cytotoxic T lymphocyte associated antigen 4, and mannose-binding lectin. In this review we will present what is known, what is disputed, and what remains to be discovered in the world of lupus genetics.
Synthesis of 2′- and 2″-O-acylated maltotriosides as potential fluorescence-quenched substrates for α-amylase (1994)

Several 2′- and 2″-O-acylated maltotrioside derivatives have been prepared as substrates for use in fluorescence-quenched assays of α-amylase. These maltotriosides carry a quenching group [2-(4-hydroxy-3-nitrophenyl)ethyl] at the reducing end and a fluorescent donor (2-aminobenzoyl) at either of the non-reducing D-glucose units. The quenching groups were introduced via silver triflate-promoted glycosylation, whilst several methods were investigated for the selective introduction of the fluorescent group. Attempted enzymic acylation of the maltotriosides with subtilisin in neat dimethylformamide gave the 2′- and 2″-O-acylated derivatives as the major products. These were shown to be the products of chemical rather than enzymic acylation, in contrast to the analogous literature reaction with maltotriose. Intramolecular quenching of the compounds was demonstrated by measuring the increase in fluorescence upon hydrolysis.
Heterodyne Measurement System (HMS) for Determining Phase Angles (2007)

This paper describes a method to determine the phase angle between two voltages via complex ratio of frequency-shifted sinusoidal signals. This allows the use of precision-sampling methods for signals with frequencies up to the audio-frequency range and with rms voltage levels up to 7 V and a maximum voltage ratio of 1:10
Del intraducible lenguaje teatral (2011)

Histricamente, el teatro ha empleado una doble estrategia frente a la competencia de nuevos medios de comunicacin como el cine, la televisin, el vdeo, etc.: 1) la incorporacin funcional de los nuevos elementos tcnicos en su propia potica y 2) el retorno al ncleo insustituible de su modo de ser e intraducible por el lenguaje de otros medios, particularmente al dilogo bidireccional entre el escenario y la
Microfluidic pumps employing surface acoustic waves generated in ZnO thin films (2009)

ZnO thin film based surface acoustic wave (SAW) devices have been utilized to fabricate microfluidic pumps. The SAW devices were fabricated on nanocrystalline ZnO piezoelectric thin films deposited on Si substrates using rf magnetron sputtering and use a Sezawa wave mode for effective droplet motion. The as-deposited ZnO surface is hydrophilic, with a water contact angle of ∼75°, which prevents droplet pumping. Therefore, the ZnO surface was coated using a self-assembled monolayer of octadecyltrichlorosilane which forms a hydrophobic surface with a water contact angle of ∼110°. Liquid droplets between 0.5 and 1 μl in volume were successfully pumped on the hydrophobic ZnO surface at velocities up to 1 cm s−1. Under acoustic pressure, the water droplet on an hydrophilic surface becomes deformed, and the asymmetry in the contact angle at the trailing and leading edges allow the force acting upon the droplet to be calculated. These forces, which increase with input voltage above a threshold level, are found to be in the range of ∼100 μN. A pulsed rf signal has also been used to demonstrate precision manipulation of the liquid droplets. Furthermore, a SAW device structure is demonstrated in which the ZnO piezoelectric only exists under the input and output transducers. This structure still permits pumping, while avoiding direct contact between the piezoelectric material and the fluid. This is of particular importance for biological laboratory-on-a-chip applications.
A New Cadmium Reduction Device for the Microplate Determination of Nitrate in Water, Soil, Plant Tissue, and Physiological Fluids (2011)

A reusable catalytic reductor consisting of 96 copperized-cadmium pins attached to a microplate lid was developed to simultaneously reduce nitrate (NO3-) to nitrite (NO2-) in all wells of a standard microplate. The resulting NO2- is analyzed colorimetrically by the Griess reaction using a microplate reader. Nitrate data from groundwater samples analyzed using the new device correlated well with data obtained by ion chromatography (r2 = 0.9959). Soil and plant tissue samples previously analyzed for NO3- in an interlaboratory validation study sponsored by the Soil Science Society of America were also analyzed using the new technique. For the soil sample set, the data are shown to correlate well with the other methods used (r2 = 0.9976). Plant data correlated less well, especially for samples containing low concentrations of NO3-. Reasons for these discrepancies are discussed, and new techniques to increase the accuracy of the analysis are explored. In addition, a method is presented for analyzing NO3- in physiological fluids (blood serum and urine) after matrix modification with Somogyi's reagent. A protocol for statistical validation of data when analyzing samples with complex matrixes is also established. The simplicity, adaptability, and low cost of the device indicate its potential for widespread application.
Feature extraction using Deep Learning for Intrusion Detection System (2019)

Deep Learning is an area of Machine Learning research, which can be used to manipulate large amount of information in an intelligent way by using the functionality of computational intelligence. A deep learning system is a fully trainable system beginning from raw input to the final output of recognized objects. Feature selection is an important aspect of deep learning which can be applied for dimensionality reduction or attribute reduction and making the information more explicit and usable. Deep learning can build various learning models which can abstract unknown information by selecting a subset of relevant features. This property of deep learning makes it useful in analysis of highly complex information one which is present in intrusive data or information flowing with in a web system or a network which needs to be analyzed to detect anomalies. Our approach combines the intelligent ability of Deep Learning to build a smart Intrusion detection system.
Intra-Patient Anatomic Statistical Models for Adaptive Radiotherapy (2006)

Abstract — A statistical issue of clinical importance is intrapatient variation from day to day. We use these probability densities for segmentation of daily images by posterior optimization of deformable models. However, the information on intra-patient variation is only available after the multiple days of imaging; yet the densities are needed for segmentation on each day. Still, each patient’s anatomy and image properties are distinct. We describe an approach of using sample means over the days so far to describe a Fréchet mean of the patient. We assume intra-patient variation is stationary across patients, so one can pool training statistics on residues from the mean of the respective patient. The approach is applied both to principal geodesic analysis of m-rep residues describing anatomic variation and to PCA of intensity quantile residues from model-relative regions. In trials to date, application of these statistics in segmentations of male pelvic organs from CT in adaptive radiotherapy yields results competitive with human segmentations and with segmentations based fully on intra-patient statistics. Index Terms — segmentation, adaptive radiotherapy, deformable model segmentation by posterior optimization of deformable models using the combination of within-patient sample means and other-patient statistics of variations. Section 2 summarizes work by others on estimating interpatient probability densities both on anatomic geometry and on intensities. It then describes our work on estimating these densities by Principal Geodesic Analysis (PGA) on m-rep geometric models and by PCA on regional intensity quantile functions (RIQFs), respectively. Section 3 describes the method for estimating intra-patient probability densities. Section 4 describes the application of these densities in the segmentation of intra-patient male pelvic organs from CT and gives results that show that segmentation by posterior optimization based on these probability densities gives results that are not only good but also as good as those given when the probability densities are estimated from all days of the particular patient. I.
Epinephrine as an inotropic agent in septic shock (1993)

Epinephrine increases DO2 in septic shock by increasing cardiac index without an effect on systemic vascular resistance index or PAOP.
All-in-focus Photo image Creation by Wavelet Transform (2006)

In this paper, we describe a deblurring method using Image-Fusion of multiple images taken with different object-distances. Our method uses the wavelet transform for the fusion, but we create new wavelet coefficients by mixing each pixel value by using reference image usage rate (IUR). And we present simple and effective algorithms Fusion rule for the lowest frequency subband Noise reduction algorithm Blur reduction algorithm that use this IUR. I. INTRODUCTION When we take a photo, we adjust the object-distance (focus position) manually or automatically to take the clear image of the photographic subject. In other words, we put the subject into the zone of focus that is called depth-of-field. However, in the case of the short object distance, the zone becomes too narrow to cover the whole region of the subject(s) and the image of such regions become unclear. But, clear regions are also contained in a photo image, so we can correct the subject image by synthesizing (fusing) images that are taken with different object distance (See Fig.1).