gebhart/patrepeval huggingface dataset:
Stability Analysis of ARINC 825-Based Partially Distributed Aircraft Engine Control with Transmission Delays and Packet Dropouts (2010)

The importance of distributed aircraft engine control architecture is well discussed in literature. The performance of distributed engine control systems is predominantly dependent on the performance of the communication network. Communication constraints such as time delays and packet dropouts can lead to inconsistent data latency, which may limit the performance of distributed engine control or in the worst case scenario, can even destabilize the control system. In this paper, we review three different partially distributed engine control architectures based on ARINC 825, a general standardization of Controller Area Network (CAN) for aerospace applications. The first architecture employs the legacy sensors & legacy actuators and uses a data concentrator to transmit the data to distributed FADEC. Second architecture, which has smart sensors and legacy actuators, makes use of state observers to provide compensation for sensor-controller time delays. In the third architecture, smart actuators allows the use of network predictive controller, which provides compensation for time delays and packet dropouts in both sensor-controller and controlleractuator communication channels. Stability conditions for each of the three architectures are presented and the three architectures are compared on the basis of performance and robustness to time delays and packet dropouts.
VEGF-A121a binding to Neuropilins – A concept revisited (2017)

All known splice isoforms of vascular endothelial growth factor A (VEGF-A) can bind to the receptor tyrosine kinases VEGFR-1 and VEGFR-2. We focus here on VEGF-A121a and VEGF-A165a, two of the most abundant VEGF-A splice isoforms in human tissue <sup>1</sup> , and their ability to bind the Neuropilin co-receptors NRP1 and NRP2. The Neuropilins are key vascular, immune, and nervous system receptors on endothelial cells, neuronal axons, and regulatory T cells respectively. They serve as co-receptors for the Plexins in Semaphorin binding on neuronal and vascular endothelial cells, and for the VEGFRs in VEGF binding on vascular and lymphatic endothelial cells, and thus regulate the initiation and coordination of cell signaling by Semaphorins and VEGFs. <sup>2</sup> There is conflicting evidence in the literature as to whether only heparin-binding VEGF-A isoforms - that is, isoforms with domains encoded by exons 6 and/or 7 plus 8a - bind to Neuropilins on endothelial cells. While it is clear that VEGF-A165a binds to both NRP1 and NRP2, published studies do not all agree on the ability of VEGF-A121a to bind NRPs. Here, we review and attempt to reconcile evidence for and against VEGF-A121a binding to Neuropilins. This evidence suggests that, in vitro, VEGF-A121a can bind to both NRP1 and NRP2 via domains encoded by exons 5 and 8a; in the case of NRP1, VEGF-A121a binds with lower affinity than VEGF-A165a. In in vitro cell culture experiments, both NRP1 and NRP2 can enhance VEGF-A121a-induced phosphorylation of VEGFR2 and downstream signaling including proliferation. However, unlike VEGFA-165a, experiments have shown that VEGF-A121a does not 'bridge' VEGFR2 and NRP1, i.e. it does not bind both receptors simultaneously at their extracellular domain. Thus, the mechanism by which Neuropilins potentiate VEGF-A121a-mediated VEGFR2 signaling may be different from that for VEGF-A165a. We suggest such an alternate mechanism: interactions between NRP1 and VEGFR2 transmembrane (TM) and intracellular (IC) domains.
A Real-Time, Automated and Privacy-Preserving Mobile Emergency-Medical-Service Network for Informing the Closest Rescuer to Rapidly Support Mobile-Emergency-Call Victims (2018)

As populations age, there is a growing need for the establishment and staffing of care centers, but the supply of such facilities is not keeping pace with demand. Existing hospitals, care centers, and other institutions currently provide care for many physically disabled and elderly patients. For these patients to go outside in the fresh air, they must necessarily leave their designated care areas, but this poses a risk of falls and other accidents, which can be particularly challenging to prevent or respond to the given staffing limitations. Such incidents can cause further physical and mental deterioration. Many studies have sought to minimize rescue response times by first establishing the incident location before alerting staff to respond. However, this approach does not guarantee minimized response times. This paper proposes an approach to allow medical staff to quickly arrive at the scene of an accident with patients and staff using mobile devices to automatically alert a central server of their current locations. In response to an accident notification, the server immediately alerts medical staff in closest proximity to the incident to respond, with the staff devices providing clear directions to reach the patient in distress, thus minimizing response times. The proposed system can operate while maintaining security and patient information privacy, including the data integrity, anonymity, authentication, location confidentiality, location unforgeability, and resistance to asynchronous and tracking attacks, and is implemented on Android smart phones. The proposed system can be used in homes, hospitals, care centers, or any other venue offering long-term care. This proposal is the first such real-time and automated emergency rescue alert system to provide both information privacy and authentication.
NON‐CORONARY HEART DISEASE IN DIALYSIS PATIENTS: Sudden Cardiac Death and Dialysis Patients (2008)

Dialysis patients have extraordinarily high mortality rates. The death rate for all US dialysis patients in 2004 was 230 per 1000 patient-years. Cardiac disease is the major cause of death in dialysis patients and accounts for 43% of all-cause mortality. In the United States Renal Data System database 62% of cardiac deaths (or 27% of all deaths) are attributable to arrhythmic mechanisms. The estimated rate of sudden cardiac death in US dialysis patients in 2002 was 7% per year. There are several plausible explanations for the special vulnerability of dialysis patients to sustaining sudden cardiac death. Obstructive coronary artery disease, coupled with diminished tolerance to myocardial ischemia (in the setting of myocardial fibrosis and left ventricular hypertrophy), rapid electrolyte shifts in hemodialysis patients, and derangements in autonomic function may all contribute to this heightened risk of sudden cardiac death. This review focuses on the epidemiology of sudden cardiac death in dialysis patients, underlying mechanisms of sudden death, and potential interventions to reduce the risk of sudden cardiac death in dialysis patients (including medical therapy and defibrillators). It is unlikely that one single therapeutic intervention will prevent sudden cardiac death in dialysis patients; but a more modest (and attainable) goal is the implementation of multiple strategies to reduce the risk of sudden cardiac death in this special high-risk population.
scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells (2020)

In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both high sequence similarity and the use of the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2), with severe acute respiratory syndrome coronavirus (SARS-CoV). Several studies have provided bioinformatic evidence of potential routes of SARS-CoV-2 infection in respiratory, cardiovascular, digestive and urinary systems. However, whether the reproductive system is a potential target of SARS-CoV-2 infection has not yet been determined. Here, we investigate the expression pattern of ACE2 in adult human testes at the level of single-cell transcriptomes. The results indicate that ACE2 is predominantly enriched in spermatogonia and Leydig and Sertoli cells. Gene Set Enrichment Analysis (GSEA) indicates that Gene Ontology (GO) categories associated with viral reproduction and transmission are highly enriched in ACE2-positive spermatogonia, while male gamete generation related terms are downregulated. Cell-cell junction and immunity-related GO terms are increased in ACE2-positive Leydig and Sertoli cells, but mitochondria and reproduction-related GO terms are decreased. These findings provide evidence that the human testis is a potential target of SARS-CoV-2 infection, which may have significant impact on our understanding of the pathophysiology of this rapidly spreading disease.
Intricacies of an Automatic Text Summarizer (2013)

The creation of an abstract over a text document prepared by a computer program is defined as an Automatic Text Summarizer. This abstract of the text document must however contain all the salient features of the original document. This paper tries to cover the necessary functional modules that complete an automatic text summarizer. It also highlights the trends and challenges in text summarization. Surveys of certain text summarization techniques are also mentioned.
México y América en mi obra compositiva (2012)

This article describes the relations of Tomas Marco, a Spanish composer, with America - both America in general and Mexico in particular - as these are reflected in several of his compositions. It also explores the continual passage or to and fro between Spain and the Americas, expressed at a general level in compositions such as Ceremonia Barroca or the Cantata America and more closely explored in the musical elements of the Sonata Atlantica. The intersections are multiple and diverse, of an historical (Ultramarina and Epitafio para Lope de Aguirre), mythical (Kukulcan) and anthropological nature. In effect, Marco has forged a new direction of musical creation influenced in various respects by America and Mexico.
2D nuclear magnetic resonance analysis of osmylated C60 (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT2D nuclear magnetic resonance analysis of osmylated C60Joel M. Hawkins, Stefan Loren, Axel Meyer, and Rudi NunlistCite this: J. Am. Chem. Soc. 1991, 113, 20, 7770–7771Publication Date (Print):September 1, 1991Publication History Published online1 May 2002Published inissue 1 September 1991https://doi.org/10.1021/ja00020a054RIGHTS & PERMISSIONSArticle Views138Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (266 KB) Get e-Alerts Get e-Alerts
Quantitative trait loci associated with lodging tolerance in soybean cultivar ‘Toyoharuka’ (2014)

Lodging tolerance (LT) is an important trait for high yield and combine-harvesting efficiency in soybean [Glycine max (L.) Merr.]. Many previous studies have investigated quantitative trait loci (QTLs) for lodging score (LS) in soybean. Most of the investigated QTLs were located in the proximal region of maturity or growth habit loci. The aim of this study was to identify genetic factors for LT not associated with maturity or growth habit. QTL analysis was performed using a recombinant inbred line (RIL) population derived from a cross between 'Toyoharuka' (TH), a lodging-tolerant cultivar, and 'Toyomusume' (TM). The genotypes of TH and TM were estimated as both e1e2E3E4 and dt1. The average LS over 4 years was used for QTL analysis, identifying a major and stable QTL, qLS19-1, on chromosome 19. The LS of the near-isogenic line (NIL) with the TH allele at Sat_099, the nearest marker to qLS19-1, was significantly lower than the NIL with the TM allele at that position. The TH allele at Sat_099 rarely had a negative influence on seed yield or other agronomic traits in both NILs and the TM-backcrossed lines. Our results suggest that marker-assisted selection for qLS19-1 is effective for improving LT in breeding programs.
In-situ Fourier transform infrared studies of reaction mechanisms in heterogeneous catalysis (1990)

An I.R. cell which can be used, in heterogeneous catalysis, as a continuous flow reactor up to 3 MPa and 575K is described. It is coupled to an on-line gas chromatograph for product analysis. It simultaneously allows recording the I.R. spectra of adsorbed species during the reaction, a pressed wafer being the catalyst. Using a FT-JR spectrometer, spectra can be recorded every 5 seconds. The system has been used to study different reactions such as i) n-hexane isomerization on H-mordenite and Pt-H-mordenite catalysts; ii) CO hydrogenation over Rh/CeO2 catalysts; iii) methanol synthesis on Cu-ZnAl2O4 catalysts with variable CO + CO2 + H2 feeds. Special attention has been paid to determine if the species which are observed are intermediates in the studied processes. In such a case, their detection provides very useful access to the reaction mechanisms. Moreover, the system allows us to follow the state of catalysts, under working conditions, for instance the degree of the zeolite deactivation or the reduction state of copper in the case of methanol catalysis.
The molecular machinery of Keilin's respiratory chain (2003)

Keilin's classic paper of 1925 [Keilin (1925) Proc. R. Soc. London Ser. B 100, 129-151], achieved with simple, but elegant, techniques, describes the cytochrome components of the respiratory chain and their roles in intracellular respiration and oxygen consumption. Since that time, a tremendous amount of work has clarified the intricate details of the prosthetic groups, cofactors and proteins that comprise the respiratory chain and associated machinery for ATP synthesis. The work has culminated in advanced crystallographic and spectroscopic methods that provide structural and mechanistic details of this mitochondrial molecular machinery, in many instances to atomic level. I review here the current state of understanding of the mitochondrial respiratory chain in terms of structures and dynamics of the component proteins and their roles in the biological electron and proton transfer processes that result in ATP synthesis. These advances, together with emerging evidence of further diverse roles of mitochondria in health and disease, have prompted a new era of interest in mitochondrial function.
The impact of network variabilities on TCP clocking schemes (2005)

TCP employs a self-clocking scheme that times the sending of packets. In that, the data packets are sent in a burst when the returning acknowledgement packets are received. This self-clocking scheme (also known as ack-clocking) is deemed a key factor to the the burstiness of TCP traffic and the source of various performance problems-high packet loss, long delay, and high delay jitter. Previous work has suggested contradictively the effectiveness of TCP pacing as a remedy to alleviate the traffic burstiness. In this paper, we analyze systematically, and in more robust experiments the impact of network variabilities on the behavior of TCP clocking schemes. We find that 1) aggregated pacing traffic could be burstier than aggregated ack-clocking traffic. Physical explanation and experimental simulations are provided to support this argument. 2) The round-trip time heterogeneity and flow multiplexing significantly influence the behaviors of both ack-clocking and pacing schemes. Evaluating the performance of clocking schemes without considering these effects is prone to inconsistent results. 3) Pacing outperforms ack-clocking in more realistic settings from the traffic burstiness point of view.
Hyperthermic radiosensitization: mode of action and clinical relevance (2001)

Since recent phase III clinical trials have shown significant benefit of adding hyperthermia to radiotherapy regimens for a number of malignancies, it will become more important again to determine the molecular effects underlying this success. Such information could eventually also improve treatment quality in terms of patient selection, improved sequencing of the heat and radiation treatments, the number of heat treatments, and multimodality treatments (i.e. thermochemoradiotherapy).
Specialization in low vision rehabilitation and visual therapy. (1991)

A questionnaire was mailed to members of the Low Vision Section (LVS) of the American Optometric Association (AOA) and the Council on Visual Development (COVD) to determine the practice patterns of low vision clinicians, amount and source of specialty training and the extent of dual specialization in both low vision rehabilitation and visual training by members of COVD. Results indicate that 61.1 percent of AOA/LVS members and 20.9 percent of COVD members examine more than four patients per month who require low vision services. Yet, only 2.1 percent of COVD respondents and 32.2 percent of AOA/LVS respondents spend more than 20 percent of their practice time providing low vision services.
Taking Stock of Outdoor Recreation Research in New Zealand: What We Do and Don't Know (2011)

The New Zealand Outdoor Recreation Strategy 2009-2015 was released by Sport and Recreation New Zealand (SPARC) in August 2009. The Strategy addresses the issues identified by a review of the outdoor recreation sector. The paper outlines two research outputs of the Strategy, namely a stocktake of existing outdoor recreation research and an outdoor recreation research agenda.
Evaluation of three methods for the measurement of crystallinity of pet resins, preforms, and bottles (2000)

Abstract The control of crystallization is important at all processing stages of the PET bottle industry, from the manufacture of bottle resins to the fabrication of preforms and bottles. In this work, we sought to evaluate critically three methods of crystallinity measurement. We have used density, Differential Scanning Calorimetry (DSC), and Modulated Differential Scanning Calorimetry (MDSC) to study the crystallinity of PET chips, preforms, and bottles. The accuracy, precision, and general validity of each technique and the problems of interpretation are discussed.
Cross‐reactivity between Acacia (wattle) and rye grass pollen allergens (1982)

Immunoglobulin E (IgE), directed against components of Acacia (wattle) pollen, has been detected by radioallergosorbent tests (RAST) in the sera of some children and adults who develop allergic symptoms in the presence of flowering Acacia trees in Australia. All these subjects also had high levels of IgE directed against Lolium perenne (rye grass) pollen. Inhibition by RAST showed that most of the IgE molecules which bound to Acacia pollen components also bound to L. perenne pollen extracts, and to Glycoprotein 1, the major allergen of L. perenne pollen. In these assays, the allergens have been immobilized on polyvinyl chloride microtitre trays: the sensitivity of this approach is compared to that of commercial RAST kits.
C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by c-jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma (2012)

Our data suggest that COOH truncation of HBx, particularly with 24 amino acids truncated at the C-terminal end, plays a role in enhancing cell invasiveness and metastasis in HCC by activating MMP10 through C-Jun.
Short‐term hydropower planning coordinated with wind power in areas with congestion problems (2007)

Abstract In this paper, a day‐ahead planning algorithm for a multi‐reservoir hydropower system coordinated with wind power is developed. Coordination applies to real situations, where wind power and hydropower are owned by different utilities, sharing the same transmission lines, although hydropower has priority for transmission capacity. Coordination is thus necessary to minimize wind energy curtailments during congestion situations. The planning algorithm accounts for the uncertainty of wind power forecast. Only planning for the spot market is considered. Once the production bid is placed on the market, it cannot be changed. The solution of the stochastic optimization problem should, therefore, fulfill the transmission constraints for all wind power production scenarios. An evaluation algorithm is also developed to quantify the impact from the coordinated planning in the long run. The developed planning algorithm and the evaluation algorithm are applied in a case study. The results are compared with uncoordinated operation. The results of the case study show that coordination with wind power brings additional income to the hydropower utility and leads to significant reduction of wind energy curtailments. Copyright © 2007 John Wiley & Sons, Ltd.
Pore-based ridge reconstruction for fingerprint recognition (2015)

The use of sweat pores in fingerprint recognition is becoming increasingly popular, mostly because of the wide availability of pores, which provides complementary information for matching distorted or incomplete images. In this work we present a fully automatic pore-based fingerprint recognition framework that combines both pores and ridges to measure the similarity of two images. To obtain the ridge structure, we propose a novel pore-based ridge reconstruction approach by considering a connect-the-dots strategy. To this end, Kruskal's minimum spanning tree algorithm is employed to connect consecutive pores and form a graph representing the ridge skeleton. We evaluate our framework on the PolyU HRF database, and the obtained results are favorably compared to previous results in the literature.
Highly Durable NOx Reduction System and Catalysts for NOx Storage Reduction System (1998)

<div class="htmlview paragraph">NOx storage-reduction catalysts have shown serious deactivation in the presence of SOx. This is because, under lean conditions, SOx adsorbs more strongly on NO<sub>2</sub> adsorption sites than NO<sub>2</sub>, and the adsorbed SOx does not desorb altogether even under rich conditions. We have solved the problem by configuring, in front of the NOx storage-reduction catalysts, SOx adsorbents that can adsorb only SOx among SOx and NOx in exhaust gases under the lean conditions and desorb the adsorbed SOx easily under the rich conditions. The catalysts can reduce NOx, CO and hydrocarbons at a high rate for a prolonged period.</div>