gebhart/patrepeval huggingface dataset:
High‐resolution <sup>13</sup>C NMR studies of proanthocyanidin polymers (condensed tannins) (1987)

Abstract High‐resolution 13 C NMR spectra of some proanthocyanidin polymers are presented. They were measured in acetone‐ d 6 ‐water (1:1, v/v ) solution at 30 °C and at 62.5 MHz. The chemical shifts of selected resonances in these spectra were compared with those of structurally related monomers and oligomers. These comparisons enable certain deductions to be made regarding the stereochemistry and mode of linkage of the constituent flavanoid monomer units of these polymers.
Bibliography of photon total cross section (attenuation coefficient) measurements 10 eV to 13.5 GeV (1986)

We present a bibliography of papers reporting absolute measurements of photon (X'JV, x-ray, gamma-ray, bremsstrahlung) total interaction cross sections or attenuation coefficients for the elements and some compounds. The energy range covered is from 10 eV to above 10 GeV.
A GIS Framework for Spatio‐temporal Analysis and Visualization of Laboratory Mice Tracking Data (2007)

Abstract Knowing the locations and spatio‐temporal paths of individual mice is an essential prerequisite for behavioral analysis of large groups of laboratory mice. Traditional observations have been carried out by trained humans who are able to distinguish more than fifty behavioral patterns. This is a tedious labor limited with respect to length of observation time. In this paper we propose a tracking solution based on the integration of GIS and RFID (Radio Frequency Identification) technology to automatically collect 24h/7days of movement data. Appropriate cage design and antenna placement are discussed. A software solution is presented to facilitate the recording (JerryTS), visualization, and analysis (TOM) of mice movements.
Non-invasive measurement of cardiac output by a single breath constant expiratory technique. (1984)

A new single breath test has been developed that measures pulmonary blood flow (Qc) and pulmonary tissue volume by using the fact that Qc is proportional to the relationship between the absorption rate of acetylene (C2H2) from the alveolar gas and the rate of change of lung volume during constant expiratory flow. To make these measurements a bag in bottle system with a rolling seal spirometer, a mass spectrometer, and a minicomputer with analogue to digital conversion have been used. Qc was compared with cardiac output measured by the thermodilution technique in 20 patients with cardiac disease; some also had mild chronic obstructive pulmonary disease. The mean (SD) resting Qc for the group was 5.27 (1.22) l/min and the cardiac output measured by thermodilution was 5.30 (1.31) l/min. The mean difference between the two estimations of cardiac output was 0.03 l and the standard deviation of this difference was 0.76 l. The Qc technique was not successful in patients with an FEV1/FVC less than 60%, but seemed to be accurate in those with higher FEV1/FVC values. Correction of Qc for the effect of venous admixture in 14 patients resulted in an average 19% overestimation of cardiac output (6.01 (2.52) l/min v 5.05 (1.64) l/min). It is concluded that cardiac output can be accurately measured in patients with cardiac or mild pulmonary disease. No correction for venous admixture due to ventilation-perfusion mismatch was necessary in these patients, presumably because the large breath used by the technique overcomes most mild ventilation-perfusion maldistribution. These findings, in addition to the non-invasive nature of the technique, suggest potential value for the measurement of cardiac output in various clinical conditions.
Ru-catalyzed highly chemo- and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters under neutral conditions (2012)

Finely-tuned ruthenium-catalyzed highly chemoselective and enantioselective hydrogenation of γ-halo-γ,δ-unsaturated-β-keto esters at the carbonyl group was achieved under neutral reaction conditions (ee up to 97%). Both olefin and alkenyl halogen moieties, which are labile under hydrogenation conditions, remained untouched during the reaction.
Effect of Calcium Phosphate Hydroxyapatite on Rheological Properties of Wheat Flour and Corn Starch (1991)

The rheological properties of wheat flours and corn starch and cooking properties of dry noodle in the presence of calcium phosphate hydroxyapatite(Ca-P) were studied. The additive() had essentially no effects on farinograms of strong and all-purpose wheat flours, however, they decreased the amylograph pasting temperature and increased the peak viscosity of flours, which was more pronounced in all-purpose flour. The cooking properties of dry noodles in the presence or absence of the Ca-P showed no significant differences, but the cutting forces of cooked noodles were increased by Ca-P at 0.4%. The pasting properties of corn starch in the presence of Ca-P() were similar to those of wheat flour. The gelatinization temperature of corn starch by differential scanning calorimeter decreased by in the presence of 0.4% Ca-P. The time constant, a reciprocal of rate constant, of corn starch gel was slightly increased in the presence of 0.2 or 0.4% Ca-P.
Proposed interferometric filters (1980)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text M. Jamil Ahmed and L. Young, "Proposed interferometric filters," Appl. Opt. 19, 3051-3052 (1980) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Intracochlear Inflammatory Response to Cochlear Implant Electrodes in Humans (2014)

An inflammatory response is common after cochlear implantation, and it is more robust at the cochleostomy than distal to it, suggesting the role of trauma of insertion as a contributing factor.
Supramolecular recognition: On the kinetic lability of thermodynamically stable host–guest association complexes (2002)

A molecular receptor consisting of a spacer bearing two cofacially disposed terpyridyl-palladium-ligand (terpy-Pd-L) units rigidly separated by about 7 A has been investigated for molecular recognition of planar aromatic molecules. It is found that although the receptor forms stable 1:2 host-guest association complexes with 9-methylanthracene (9-MA), the guest undergoes very rapid site exchange within the receptor and with external free 9-MA. A crystal structure of the 2:1 adduct shows one 9-MA in the molecular cleft defined by the two terpy-Pd-L units and the other resides on an outside face of one terpy-Pd-L unit. To establish the site residency time of the guests, a number of tethered molecules were prepared. These involve an anthracene molecule tethered to a pyridine ligand bound to the palladium atoms to form intramolecular host-guest adducts. Rotating-frame Overhauser effects were used to infer the site residency of the anthracene guests in the receptor. Variable-temperature (1)H NMR spectroscopy of the intramolecular host-guest complexes has revealed that the site residency time of the anthracene guests is 1.6 x 10(-5) sec at 20 degrees C and 1.3 sec at -90 degrees C in acetone solution. Whereas the guests are thermodynamically stable, they are kinetically very labile. A crystal structure of one of the tethered host-guest adducts reveals the expected structure which is the same as that determined in solution by (1)H rotating-frame Overhauser enhancement spectroscopy experiments.
Ether alcohol sulfates from oleyl alcohol (1967)

Abstract Oleyl alcohol was caused to react with ethylene oxide, propylene oxide, and 1,2‐butylene oxide in the presence of an alkaline catalyst. The first and second derivatives from each reaction were isolated by fractional distillation. Sulfation with dioxane‐SO 3 gave high‐purity oleyl ether sulfates, easily soluble, with good detergent and lime soap‐dispersing properties. The use of chlorosulfonic acid or sulfuric acid as the sulfating agent for oleyl ether alcohols resulted in about 60% retention of the double bond, compared with oleyl alcohol, which under the same conditions retained only about 25% unsaturation. Oleyl ether alcohols sulfated with chlorosulfuric acid or sulfuric acid are easily sobuble and have good lime soap‐dispersing properties. They are able to solubilize less soluble soaps and saturated ether alcohol sulfates.
Enlighten me! secure key assignment in wireless sensor networks (2009)

The availability of secret keys is a precondition for the use of many security solutions and protocols. However, securely assigning such keys to nodes is a challenging task in the context of wireless sensor networks. In this paper we present a novel solution for a secure key assignment in wireless sensor networks that can be used during the initial configuration of nodes or for an ad-hoc key assignment by mobile nodes. The idea is to transmit the key information over a side channel using a controllable light source as the sender and the light sensors available on wireless sensor nodes as receivers. We demonstrate that our solution fulfills the relevant security requirements while at the same time being cost effective and easy to use.
Hard-magnetic properties and microstructure of Sm(Co,Cu)<i>z</i> compounds (1976)

Magnetic measurements and metallographic investigations are reported on Sm(Co,Cu)z alloys. The compositions lie between the rare-earth (RE) to transition-metal (TM) ratios of 1 : 5 and 2 : 17 with a content of copper of up to 35% of the TM fraction. The materials were analyzed both in the as-cast and heat-treatment conditions. The remanence BR scales with composition. The coercivity IHc showed a maximum along a tieline from the off-stochiometric Sm(Co0.65Cu0.35)5.6 to the Sm2Co17 phase. In the as-cast state the hysteresis loops are not square. High-temperature homogenization yields ideal demagnetization curves. Subsequent annealing at lower temperatures T resulted in two coercivity peaks as a function of T. The peak temperatures decrease with increasing Cu concentration, e.g., for 35% Cu of TM 450 and 650 °C and for 20% Cu of TM 650 and 850 °C were found. Alloys near the 2 : 17 phase boundary contain 2 : 17 as a massive primary phase in a 1 : 5 matrix. The squareness of the hysteresis loops implies that the 2 : 17 phase itself is magnetically hardened. The results are discussed on a pinning model under consideration of the metallurgical properties of the RE-TM alloys.
The Dynamic Structure of Arterioles (2011)

Arterioles are the blood vessels in the arterial side of the vascular tree that are located proximal to the capillaries and, in conjunction with the terminal arteries, provide the majority of resistance to blood flow. Consequently, arterioles are important contributors to the regulation of mean arterial pressure and tissue perfusion. Their wall consists of cellular and extracellular components that have been traditionally classified as conforming three layers: an intima containing endothelial cells sited on a basement membrane; a media made of an internal elastic lamina apposed by one or two layers of smooth muscle; and an adventitia composed mostly of collagen bundles, nerve endings and some fibroblasts. These components of the arteriolar wall are dynamically interconnected, providing a level of plasticity to the arteriolar wall that blurs the traditional boundaries of a rigid layered classification. This MiniReview focuses on the structural conformation of the arteriolar wall and shows how wall components interact spatially, functionally and temporally to control vascular diameter, regulate blood flow and maintain vascular permeability.
New myocardial imaging agents: stabilization of radioiodine as a terminal vinyl iodide moiety on tellurium fatty acids (1983)

To determine the myocardial uptake and retention properties of radioiodinated tellurium fatty acids, we prepared two new tellurium fatty acids in which iodine-125 has been chemically stabilized by attachment as a trans-vinyl iodide (I-CH = CH-R-Te-R'-COOH) and evaluated them in rats. Fabrication of 18-iodo-13-tellura-17-octadecenoic acid was accomplished by coupling 1,5-diiodo-1-pentene with sodium 12-(methoxycarbonyl)-n-dodecan-1-yl telluride. The [5-125I]-1,5-diiodo-1-pentene was prepared by an organoborane technique involving 125I+ treatment of 5-iodo-1-penten-1-ylboronic acid [I(CH2)3CH = CHB(OH)2]. The absolute heart uptake of this agent was moderate (1.47-2.52% dose/g after 60 min), but the heart/blood ratios were low (approximately 2.6:1). Only marginal in vivo deiodination occurred, since the thyroid uptake was low (15-18% dose/g after 60 min). The effect of tellurium in position 13 was unexpected. To determine if the low heart specificity and low heart/blood ratios were dependent upon the position of the tellurium, we prepared an analogue with the same chain length, 18-[125I]iodo-7-tellura-17-octadecenoic acid, in the same manner by reaction of [11-125I]-1,11-diiodo-1-undecene with sodium 6-(methoxycarbonyl)-n-hexan-1-yl telluride. This agent showed pronounced heart uptake (2.47-3.94% dose/g after 60 min) and prolonged retention (1.76-3.14% dose/g after 4 h) in rats. Furthermore, the heart/blood ratios remained high for several hours (13:1 after 60 min; 9:1 after 4 h). Iodine-123 labeled 18-iodo-7-tellura-17-octadecenoic acid is an attractive new compound for evaluation as a myocardial imaging agent.
Retinoic acid regulates the development of oligodendrocyte precursor cells in vitro (1994)

Cultures of oligodendrocyte precursor cells can be grown from brain hemispheres of newborn rats. These cells, also called O-2A progenitor cells, can differentiate in vitro into oligodendrocytes or type 2 astrocytes. Basic FGF and PDGF are known to stimulate their proliferation and delay their differentiation. Lack or excess of retinoic acid (RA) has been known for a long time to alter brain development suggesting that this compound is involved in normal brain development. Here we report that RA partially inhibits both the proliferation and the differentiation of oligodendrocyte precursor cells. It also down-regulates the mitogenic effect of bFGF on these cells while keeping them in an immature stage. RA is more effective than bFGF in inhibiting myelin basic protein mRNA expression in these cells, and like bFGF, it preserves their bipotential character. RA nuclear receptors RAR-alpha and their transcripts are expressed in oligodendrocyte precursor cells as seen by Western blot, Northern blot and in situ hybridization. The expression of RAR-alpha transcripts is stimulated transiently by RA alone or associated to bFGF. The expression of RAR-beta transcripts is not constitutive and is induced by RA alone or associated to bFGF and to a lesser extent by bFGF alone. These results suggest that retinoids participate in the control of the development of glial cells of the oligodendrocyte lineage.
Inhibition of cholesterol synthesis by oxygenated sterols (1978)

Sterols derived from cholesterol by introducing a ketone or hydroxyl function in the 6, 7, 15, 20, 22, 24, or 25 positions are known to be potent inhibitors of sterol synthesis in cell cultures. To gain more information regarding structural requirements for inhibitory activity, inhibitory potencies were determined for a series of 18 C27-steroids with various combinations of ketone and hydroxyl functions substituted in positions 3, 4, 5, 6, and 7, or with a single ketone or hydroxyl function in one of these positions. The effects of nuclear double bonds upon inhibitory activity were also examined. A ketone or hydroxyl function in position 3 and a second ketone or hydroxyl function in position 6 or 7 was required for inhibitory activity with two kinds of cell culture. A 3beta5alpha6beta-triol was not more inhibitory than a comparable 3beta,6beta-diol. Cholestane-3beta 5alpha-diol inhibited sterol synthesis in L cells but not in liver cell cultures. The inhibitory activities of 7-oxygenated sterols were not markedly affected by the presence of a double bond in position 4 or 5. Current knowledge of the mechanism through which the oxygenated sterols suppress cholesterol synthesis is reviewed.
Prostate-Specific Membrane Antigen-Based Therapeutics (2011)

Prostate cancer (PC) is the most common noncutaneous malignancy affecting men in the US, leading to significant morbidity and mortality. While significant therapeutic advances have been made, available systemic therapeutic options are lacking. Prostate-specific membrane antigen (PSMA) is a highly-restricted prostate cell-surface antigen that may be targeted. While initial anti-PSMA monoclonal antibodies were suboptimal, the development of monoclonal antibodies such as J591 which are highly specific for the external domain of PSMA has allowed targeting of viable, intact prostate cancer cells. Radiolabeled J591 has demonstrated accurate and selective tumor targeting, safety, and efficacy. Ongoing studies using anti-PSMA radioimmunotherapy with (177)Lu-J591 seek to improve the therapeutic profile, select optimal candidates with biomarkers, combine with chemotherapy, and prevent or delay the onset of metastatic disease for men with biochemical relapse. Anti-PSMA monoclonal antibody-drug conjugates have also been developed with completed and ongoing early-phase clinical trials. As PSMA is a selective antigen that is highly overexpressed in prostate cancer, anti-PSMA-based immunotherapy has also been studied and utilized in clinical trials.
A Study on the Characteristics of Prematurely Discharged Patients and the Model for Predicting Premature Discharge (2002)

Background : We developed a model for predicting premature discharge and identifying related factors. Methods : Prediction model was developed by data mining techniques. Basic data were collected from the total discharge data base of a university hospital in Chungnam Province during the period from July 1, 1999 to June 30, 2000. Results : 1. Among 22,873 patients, the number of patients discharged with usual discharge orders were 21,695 or 94.8%. The number of the prematurely discharged patients were 1,178 or 5.2%. 2. The primary reason for unusual discharge was transfer to other hospital. Move to a local hospital closer to their home and burdensome medical expenses were main reasons. 3. Predictability of each model was tested using the top 10 percent of patients with the highest probabilities of premature discharge. The neural network model was chosen as the most appropriate model for predicting prematurely discharged patients. 4. Ten percent of the total number of patients had been selected randomly to test the effectiveness of the neural network model. We have chosen the threshold of the neural network model as 0.7. The number of patients who were expected to discharge prematurely was 312. Among them, 241 had been discharged prematurely (77.2%). Conclusion : Of the several data mining techniques used, the neural network model was the most effective, It can be used to identify and manage the patients who are expected to discharge prematurely.
Quantum yield variation across the three pathways of photosynthesis: not yet out of the dark (2007)

The convergent quantum yield hypothesis (CQY) assumes that thermodynamics and natural selection jointly limit variation in the maximum energetic efficiency of photosynthesis in low light under otherwise specified conditions (e.g. temperature and CO(2) concentration). A literature survey of photosynthetic quantum yield (phi) studies in terrestrial plants from C(3), C(4), and CAM photosynthetic types was conducted to test the CQY hypothesis. Broad variation in phi values from C(3) plants could partially be explained by accounting for whether the measuring conditions were permissive or restrictive for photorespiration. Assimilatory quotients (AQ), calculated from the CO(2) phi:O(2) phi ratios, indicated that 49% and 29% of absorbed light energy was allocated to carbon fixation and photorespiration in C(3) plants, respectively. The unexplained remainder (22%) may represent diversion to various other energy-demanding processes (e.g. starch synthesis, nitrogen assimilation). Individual and cumulative effects of these other processes on photosynthetic efficiency are poorly quantified. In C(4) plants, little variation in phi values was observed, consistent with the fact that C(4) plants exhibit little photorespiration. As before, AQ values indicate that 22% of absorbed light energy cannot be accounted for by carbon fixation in C(4) plants. Among all three photosynthetic types, the phi of photosynthesis in CAM plants is the least studied, appears to be highly variable, and may present the greatest challenge to the CQY hypothesis. The high amount of energy diverted to processes other than carbon fixation in C(3) and C(4) plants and the poor characterization of photosynthetic efficiency in CAM plants are significant deficiencies in our otherwise robust understanding of the energetics of terrestrial photoautotrophy.
On the advantages of location resolved input data for throughput optimization algorithms in self-organizing wireless networks (2013)

Performing and evaluating Call Trace (CT) or also called Minimization of Drive Test (MDT) measurements entails additional expenses to the operator as well as to the users. However, by using location specific network data obtained from the measurements as additional information for self-organization procedures, we expect these procedures to perform essentially better since they can take their decisions upon an improved knowledge base. In this paper, we investigate the performance gain induced by the use of location specific input data for self-organization procedures. For this purpose we propose, evaluate, and compare two force field based algorithms, which are dedicated to optimizing the coverage as well as the user throughput in a macro cell deployment with heterogeneous traffic demand. The results of this work confirm the expectations: It is shown that using the additional location specific information the self-organization procedure investigated leads to higher average throughput gains and an improved robustness in the sense that the procedure was able to successfully handle all scenarios investigated.
A new neural network for cluster-detection-and-labeling (1998)

We propose in this paper a new unsupervised neural network which is capable of clustering a set of experimental data according to a given generic interpoint similarity measure, and then assign to each new input its appropriate cluster label. The network is able to do this for clusters of any shape, and without knowing in advance the number of clusters to be created. We call this new two-layer network a cluster-detection-and-labeling (CDL) network. In the CDL network the concept of similarity and closeness with regard to distance are combined. Specifically, clusters are represented by a set of prototypes, and the similarities between an input vector and these prototypes are calculated as the inner products of these vectors compared to some thresholds. These thresholds, which depend on the distance between the input vector and the prototype, are calculated in a separate threshold calculating unit. During clustering, the data are cycled through the network several times. At the end of each cycle the clusters are evaluated, and only those with more than a specified number of samples are retained. The others are fed back to be reclustered by an updated network. This process terminates according to a suitable criterion, such as when a prespecified portion of the data are classified. The performance of the CDL network has been compared with that of the winner-take-all (WTA) network for several different cluster structures, since the latter is widely used in cluster analysis applications. These studies demonstrate that the new network performs well for all the tested cluster shapes, also for those cases where the WTA network completely fails.