gebhart/patrepeval huggingface dataset:
Anti-La/SSB antibody is present in some normal sera and is coincident with anti-Ro/SSA precipitins in systemic lupus erythematosus. (1984)

Sera from 42 patients with systemic lupus erythematosus (SLE) and precipitating antibody to the La/SSB antigen contained 80,000 to 28,800,000 times the minimum detectable binding activity (units) in a solid phase ELISA assay using purified La/SSB antigen. Three normal sera (of 40 tested) had 7,200,21,600 and 21,100 units, respectively, while the log average of the 40 normals was 270 units. Binding activity in normal sera was in the F(ab')2 fragments of IgG, inhibited by purified La/SSB antigen, and bound the major La/SSB peptides. The average apparent relative binding affinity to La/SSB in normal donors was 10-fold lower than in SLE patients with anti-La/SSB precipitins. Analysis of other SLE sera revealed a high incidence of anti-La/SSB in association with anti-Ro/SSA precipitins.
Temporal motifs reveal homophily, gender-specific patterns, and group talk in call sequences (2013)

Recent studies on electronic communication records have shown that human communication has complex temporal structure. We study how communication patterns that involve multiple individuals are affected by attributes such as sex and age. To this end, we represent the communication records as a colored temporal network where node color is used to represent individuals' attributes, and identify patterns known as temporal motifs. We then construct a null model for the occurrence of temporal motifs that takes into account the interaction frequencies and connectivity between nodes of different colors. This null model allows us to detect significant patterns in call sequences that cannot be observed in a static network that uses interaction frequencies as link weights. We find sex-related differences in communication patterns in a large dataset of mobile phone records and show the existence of temporal homophily, the tendency of similar individuals to participate in communication patterns beyond what would be expected on the basis of their average interaction frequencies. We also show that temporal patterns differ between dense and sparse neighborhoods in the network. Because also this result is independent of interaction frequencies, it can be seen as an extension of Granovetter's hypothesis to temporal networks.
GPS-SLAM: An Augmentation of the ORB-SLAM Algorithm (2019)

This work presents Global Positioning System-Simultaneous Localization and Mapping (GPS-SLAM), an augmented version of Oriented FAST (Features from accelerated segment test) and Rotated BRIEF (Binary Robust Independent Elementary Features) feature detector (ORB)-SLAM using GPS and inertial data to make the algorithm capable of dealing with low frame rate datasets. In general, SLAM systems are successful in case of datasets with a high frame rate. This work was motivated by a scarce dataset where ORB-SLAM often loses track because of the lack of continuity. The main work includes the determination of the next frame's pose based on the GPS and inertial data. The results show that this additional information makes the algorithm more robust. As many large, outdoor unmanned aerial vehicle (UAV) flights save the GPS and inertial measurement unit (IMU) data of the capturing of images, this program gives an option to use the SLAM algorithm successfully even if the dataset has a low frame rate.
Wavelengths for port wine stain laser treatment: influence of vessel radius and skin anatomy (1997)

Recent Monte Carlo computations in realistic port wine stain (PWS) models containing numerous uniformly distributed vessels suggest equal depth of vascular injury at wavelengths of 577 and 585 nm. This finding contradicts clinical experience and previous theory. From a skin model containing normal and PWS vessels in separate dermal layers, we estimate analytically the average volumetric heat production in the deepest targeted PWS vessel. The fluence rate distribution is approximated by Beer's law, which depends upon the tissue's effective attenuation coefficient, and includes a homogeneous fractional volumetric blood concentration corrected for finite-size blood vessels. The model predicts 585-587 nm wavelengths are optimal in adult PWSs containing at least one layer of small-radius blood vessels. In superficial PWSs, typically in young children with small-radius vessels, 577-580 nm wavelengths are optimal. Wavelength-independent results similar to those from Monte Carlo models are valid in single-layered PWSs of large-radius vessels. In conclusion, the volumetric heat production in the deepest targeted PWS blood vessel can be maximized on an individual patient basis. However, absorption of 585-587 nm wavelengths is sufficiently high in superficial lesions, so we hypothesize that these wavelengths may be considered adequate for the treatment of any PWS
Toward Barrier Free Contact to Molybdenum Disulfide Using Graphene Electrodes (2015)

Two-dimensional layered semiconductors such as molybdenum disulfide (MoS2) have attracted tremendous interest as a new class of electronic materials. However, there are considerable challenges in making reliable contacts to these atomically thin materials. Here we present a new strategy by using graphene as the back electrodes to achieve ohmic contact to MoS2. With a finite density of states, the Fermi level of graphene can be readily tuned by a gate potential to enable a nearly perfect band alignment with MoS2. We demonstrate for the first time a transparent contact to MoS2 with zero contact barrier and linear output behavior at cryogenic temperatures (down to 1.9 K) for both monolayer and multilayer MoS2. Benefiting from the barrier-free transparent contacts, we show that a metal-insulator transition can be observed in a two-terminal MoS2 device, a phenomenon that could be easily masked by Schottky barriers found in conventional metal-contacted MoS2 devices. With further passivation by boron nitride (BN) encapsulation, we demonstrate a record-high extrinsic (two-terminal) field effect mobility up to 1300 cm(2)/(V s) in MoS2 at low temperature.
A Queueing Network Analysis of Computer Communication Networks with Window Flow Control (1979)

A computer communication network with window flow control is modeled by a closed multichain queueing network. The severe computational limitation of previous solution algorithms is overcome with a heuristic derived from the recently found mean value analysis. A large numerical example is given.
Nag Panchami: Snakes, Sex, and Semen (1992)

Abstract Nag Panchami (Snake's [Cobra's] Fifth) is a minor festival celebrated throughout North India in the latter half of July on the fifth day of the light half of the Hindu month Shravan. As the name implies, Nag Panchami is a festival in honor of snakes. Gurus are honored, patrons are recognized, and wrestlers demonstrate their skill and strength before crowds of people. It is said that even people who are not usually interested in wrestling take this opportunity to get involved. Although most people get involved only as spectators, at many akharas the pit is turned into a public arena where anyone may challenge anyone else regardless of whether they know how to wrestle or not. The chapter offers an interpretation of the symbolic structure of wrestling as a way of life, since wrestlers are seriously preoccupied with their sexuality.
Whether laparoscopic operation will be the gold standard for the surgical treatment of gastrointestinal neoplasms (2011)

In comparison with open surgery,laparoscopic surgery is more beneficial for patients with gastrointestinal neoplasms in serveral aspects,including better preservation of gastrointestinal and pulmonary function,less immunosuppression,shorter hospital stay and improved postoperative recovery.However,this minimally invasive surgery is more technically complex and hasn't got enough consent by patients.To improve the long-term outcomes,the laparoscopic techniques need to be standardized and carried out by skilled surgeons.Based on the reviewed advancement in this field and our own experience,we believe that laparoscopic surgery would be increasingly adopted as the gold standard for gastrointestinal neoplasms when its efficacy has been proved by adequate evidence from randomized controlled trials in the near future.

Key words: 
Gastric neoplasms; Colorectal neoplasms; Laparoscopy; Surgical procedures,minimally invasive
Características clínico - epidemiológicas de las cardiopatías congénitas. Clinical-epidemiological characteristics of congenital heart defects (1999)

Con el objetivo de conocer algunas caracteristicas clinico - epidemiologicos en recien nacidos con cardiopatias congenitas, se realizo un estudio prospectivo longitudinal y analitico entre los nacimientos ocurridos en el Hospital Gineco-obstetrico provincial Justo Legon Padilla de Pinar del Rio, desde enero-96 hasta diciembre-97. Se estudiaron 11,234 nacidos vivos, diagnosticandosele una cardiopatia congenita a 63 de ellos, se evaluaron criterios clinicos, electrocardiograficos y ecocardiograficos. Para el procesamiento estadistico se utilizaron bases de datos de Microsoft Excel-97, aplicandosele analisis porcentual y/o chi cuadrado, segun fuera necesario con un nivel de significacion p< 0.05.Se observo una incidencia de cardiopatias congenitas de 56.07x 10 000 nacidos vivos, con 14 fallecidos, para una totalidad del 22.2%, para una letalidad del 22.2%, con predominio del sexo masculino aunque no resulto estadisticamente significativo, asi como una tasa de mortalidad de 1.24x 1000 nacidos vivos. Las cardiopatias congenitas mas frecuentes fueron los defectos septales interventriculares aislados (61.8 %), siendo la aparicion del soplo (95.2%) la forma de debut clinico mas frecuente y la etiologia poligenica multifactorial estuvo presente en el (85.6%) de los casos. Se le realizo eco cardiografia al 100% de los casos estudio necrosico a todos los fallecidos para el completamiento del estudio. DeCS: CARDIOPATIAS CONGENITAS, ANOMALIAS. ABSTRACT A prospective, longitudinal and analytic study to know some Clinical and epidemiological characteristics of the newborns with congenital cardiopathies was conducted at Justo Legon Padilla Gyneco-Obstetric Hospital, Pinar del Rio, between January, 1996 and December, 1997. During this period, 11.234 live births were studied, 63 of them had a congenital cardiopathy diagnosis, based upon the valoration of clinical, electrocardiographic and echocardiographic criteria. Databases of Microsoft Excel-97, using percentage analysis and shi-square test, were used for the statistical analysis, signification level p< 0.05. Congenital cardiopathies had an incidence of 56.07 x 10 000 live births, with 14 deaths (fatality, 22.2%), masculine sex was predominant, although it wasn't statistically significant; mortality rate was of 1.24 x 100 live births. The most frequent congenital cardiopathies were the isolated intraventricular septal defects (61.8%), being cardiac murmur apparition (95.2%) a main sign of clinical debut, and multifactorial polygenic ethiology was noted in all the cases and a necropsy study was conducted in all the dead babies to complete the investigation. DeCS: HEART DEFECT , CONGENITAL/ Epidemiology
Use of sonic tomography to detect and quantify wood decay in living trees (2016)

Sonic tomography, coupled with image analysis, provides an efficient, noninvasive approach to evaluate decay patterns and structural integrity of even irregularly shaped living trees.
VTS 1999 Keynote Address Embedded Test OR External Test (1999)

Manufacturing test of microelectronics integrated circuits and products based thereon has now become one of the most challenging problems facing the semiconductor industry. There are several fundamental challenges such as potential yield loss due to tester accuracy relative to the devices being tested; exponentially increasing cost of new testers; and a lack of effective and viable means for failure analysis. All of these problems have been described very eloquently by the two previous keynote addresses at VTS.This talk will explore the solution needed for these problems. The concept of embedded test will be described in detail with its applicability to real ICs and products. Also explored will be the business impact of embedded test and why it must live together with external test to provide the best solution for many years to come. This combination of embedded and external tests will be seen as the most critical development of the microelectronics test industry.
Suppression of plasma testosterone and prostate carcinoma size by a redox‐based, brain‐targeted estrogen delivery system in the rat (1993)

Studies were undertaken to examine the effects of an estradiol-chemical delivery system (E2-CDS) or castration (CAST) on plasma testosterone (T) and growth of the Segaloff 11095 carcinoma. Fischer 344 rats were implanted subcutaneously with the Segaloff 11095 tumor and tumor growth was monitored thereafter. After optimal tumor growth, when the average tumor size was approximately 25 x 15 mm (length x width; 4-5 g wet weight), rats were randomized into (1) testis-intact controls; (2) CAST; (3) intact+E2-CDS groups (rats received weekly injection of the E2-CDS at 0.5 mg/kg). Animals were killed 7 or 14 days after the initiation of treatments. Blood and tissue samples were collected for subsequent analysis. Plasma T levels were suppressed by 98% and 97% through 14 days after CAST or E2-CDS treatment. CAST increased plasma gonadotropin (LH) concentrations, while E2-CDS reduced LH compared to intact control levels. E2-CDS treatment increased plasma E2 levels to 24 (one injection) or 75 pg/ml (two injections) at 7 or 14 days, respectively. E2-CDS, given once a week for 2 consecutive weeks, resulted in a decreased growth of the prostate tumor by 61%, while CAST reduced the weights of these tumors by only 20%. In response to E2-CDS (one or two injections), weights of the in situ ventral prostate and seminal vesicles were significantly reduced by 70% and 50%, respectively, in tumor-bearing rats. Similarly, CAST reduced the weights of these tissues by 80% (prostate) or 52% (seminal vesicle) at 7 or 14 days after treatment. Pituitary weight increased, while testes weight decreased by 20% with two injections of E2-CDS, compared with intact control rats. Collectively, these data indicate that E2-CDS is effective in reducing the growth rate of prostatic tumors in the rat.
Implicit meshes for surface reconstruction (2006)

Deformable 3D models can be represented either as traditional explicit surfaces, such as triangulated meshes, or as implicit surfaces. Explicit surfaces are widely accepted because they are simple to deform and render, but fitting them involves minimizing a nondifferentiable distance function. By contrast, implicit surfaces allow fitting by minimizing a differentiable algebraic distance, but are harder to meaningfully deform and render. Here, we propose a method that combines the strength of both approaches. It relies on a technique that can turn a completely arbitrary triangulated mesh, such as one taken from the Web, into an implicit surface that closely approximates it and can deform in tandem with it. This allows both automated algorithms to take advantage of the attractive properties of implicit surfaces for fitting purposes and people to use standard deformation tools they feel comfortable for interaction and animation purposes. We demonstrate the applicability of our technique to modeling the human upper-body, including face, neck, shoulders, and ears, from noisy stereo and silhouette data.
Low kappa, narrow bandwidth Si_3N_4 Bragg gratings (2015)

We investigate three approaches to low perturbation gratings to achieve lower linewidths in filters and semiconductor lasers. The three designs, which are labeled post, sampled, and high order, are DUV lithography compatible and were fabricated on 90 nm thick Si(3)N(4) strip waveguides. Reflection and transmission spectra measurements show coupling constant, kappa, values ranging from 0.23 cm(‑1) to 1.2 cm(‑1) with FWHM values of 74 pm to 116 pm. We discuss the tradeoffs between these geometries in terms of lowest linewidth, apodization, and curved waveguide layout. These results enable long cavity single mode lasers with kHz level linewidths on a monolithic platform.
DOTA: A Large-scale Dataset for Object Detection in Aerial Images (2017)

Example datasets of the Interactive Feature Localization in Deep neural networks (IFeaLiD) tool. <strong>Cityscapes</strong> These datasets are based on the image <code>bielefeld_000000_007186_leftImg8bit.png</code> of the Cityscapes dataset. The datasets can be explored online in IFeaLiD: conv2_x (<code>bielefeld_000000_007186_leftImg8bit.png.C1.npz.8.zip</code>) conv3_x (<code>bielefeld_000000_007186_leftImg8bit.png.C2.npz.8.zip</code>) conv4_x (<code>bielefeld_000000_007186_leftImg8bit.png.C3.npz.8.zip</code>) <strong>COCO</strong> These datasets are based on the image <code>000000015746.jpg</code> of the COCO dataset. The datasets can be explored online in IFeaLiD: conv2_x (<code>000000015746.jpg.C1.npz.8.zip</code>) conv3_x (<code>000000015746.jpg.C2.npz.8.zip</code>) conv4_x (<code>000000015746.jpg.C3.npz.8.zip</code>) <strong>DIV2K</strong> These datasets are based on the image <code>0804.png</code> of the DIV2K dataset. The datasets can be explored online in IFeaLiD: conv2_x (<code>0804.png.C1.npz.8.zip</code>) conv3_x (<code>0804.png.C2.npz.8.zip</code>) conv4_x (<code>0804.png.C3.npz.8.zip</code>) <strong>DOTA</strong> These datasets are based on the image <code>P0034.png</code> of the DOTA dataset. The datasets can be explored online in IFeaLiD: conv2_x (<code>P0034.png.C1.npz.8.zip</code>) conv3_x (<code>P0034.png.C2.npz.8.zip</code>) conv4_x (<code>P0034.png.C3.npz.8.zip</code>)
Using Clustered Voltage Scaling with Variable Supply-Voltage Scheme (1998)

A 60-mW MPEG4 video codec has been developed for mobile multimedia applications. This codec supports both the H.263 ITU-T recommendation and the simple profile of MPEG4 committee draft version 1 released in November 1997. It is composed of a 16-bit reduced instruction set computer processor and several dedicated hardware engines so as to satisfy both power efficiency and programmability. It performs 10 frames/s of encoding and decoding with quarter-common intermediate format at 30 MHz. Several innovative low-power techniques were employed in both architectural and circuit levels, and the final power dissipation is 60 mW at 30 MHz, which is only 30% of the power dissipation for a conventional CMOS design. The chip was fabricated in a 0.3- m CMOS with double-well and triple- metal technology. It contains 3 million transistors, including a 52-kB on-chip SRAM. Internal supply voltages of 2.5 and 1.75 V are generated by on-chip dc-dc converters from 3.3-V external supply voltage.
Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of Metformin (2015)

Our findings establish a link between mtDNA in NETs, anti-mtDNA antibodies, and PDC IFNα pathogenesis in SLE, and highlight that specific strategies to down-regulate this pathway, such as treatment with metformin, may be new approaches to treat SLE.
Single-step fabrication of quantum funnels via centrifugal colloidal casting of nanoparticle films (2015)

Centrifugal casting of composites and ceramics has been widely employed to improve the mechanical and thermal properties of functional materials. This powerful method has yet to be deployed in the context of nanoparticles--yet size-effect tuning of quantum dots is among their most distinctive and application-relevant features. Here we report the first gradient nanoparticle films to be constructed in a single step. By creating a stable colloid of nanoparticles that are capped with electronic-conduction-compatible ligands we were able to leverage centrifugal casting for thin-films devices. This new method, termed centrifugal colloidal casting, is demonstrated to form films in a bandgap-ordered manner with efficient carrier funnelling towards the lowest energy layer. We constructed the first quantum-gradient photodiode to be formed in a single deposition step and, as a result of the gradient-enhanced electric field, experimentally measured the highest normalized detectivity of any colloidal quantum dot photodetector.
Photonic crystal properties of self-assembled Archimedean tilings (2017)

Inspired by self-assembly of binary colloidal mixtures, we simulate the photonic properties of Archimedean tilings composed of triangular and square cross-section rods. Large isotropic photonic bandgaps up to 29.6% (TE) and 29.3% (TM) are found for the 32·4·3·4 Archimedean tiling due to its high rotational symmetry. For each particle geometry, the relative dielectric contrasts were varied independently over the range ε = 2 to 16, consistent with the assembly of binary materials. Mode field distributions indicate that the bandgaps originate from Lorenz-Mie scattering for high dielectric particles in an air matrix (i.e., direct structures). For the inverted structures, bandgaps arise due to the redistribution of the mode field into air pores or into complementary regions of the high dielectric material. Equifrequency contour analysis and finite difference time domain simulations are performed for direct structures with high ε square rods and low ε triangular rods and vice versa. Negative refraction occurs at nearly all angles of incidence for a relative frequency of 0.27, and sub-wavelength imaging is demonstrated for the photonic crystal flatlens with a half-wave distance of 0.45λ. Self-collimation is observed for incident angles in the range (−45°, 45°). Additionally, a waveguide with the 32·4·3·4 structure displays slow light-based signal enhancement.
Thermal Decomposition of BAMO/HMX Propellants (1993)

Abstract Thermal decomposition of BAMO [bis(azidomethyl)oxetane/tetrahydrofuran copolymer]/HMX composite propellants was studied by isothermal TGA (thermogravimetric analysis) and DSC (differential scanning calorimetry) in helium atmosphere, which was showing overall two steps first‐order kinetics. The effects of cross‐link ratio on the accelerated aging of the BAMO/HMX propellants were also measured with infrared spectroscopy and gas chromatography. The accelerated aging was conducted at 347 K for several weeks. BAMO/HMX propellants for a very low cross‐link ratio made the cavity between HMX and BAMO binder by N 2 , CO 2 , and H 2 O evolutions during accelerated aging. An exotherm, generated by the decomposition of azide binder, initiated and accelerated the thermal decomposition of HMX. The burning rate of BAMO/HMX propellant was larger than those of BAMO binder and HMX, respectively. However, the propellant could not maintain the combustion at low pressure, at which its burning rate was equal to that of BAMO binder.
The archaeal “7 kDa DNA-binding” proteins: extended characterization of an old gifted family (2016)

The "7 kDa DNA-binding" family, also known as the Sul7d family, is composed of chromatin proteins from the Sulfolobales archaeal order. Among them, Sac7d and Sso7d have been the focus of several studies with some characterization of their properties. Here, we studied eleven other proteins alongside Sac7d and Sso7d under the same conditions. The dissociation constants of the purified proteins for binding to double-stranded DNA (dsDNA) were determined in phosphate-buffered saline at 25 °C and were in the range from 11 μM to 22 μM with a preference for G/C rich sequences. In accordance with the extremophilic origin of their hosts, the proteins were found highly stable from pH 0 to pH 12 and at temperatures from 85.5 °C to 100 °C. Thus, these results validate eight putative "7 kDa DNA-binding" family proteins and show that they behave similarly regarding both their function and their stability among various genera and species. As Sac7d and Sso7d have found numerous uses as molecular biology reagents and artificial affinity proteins, this study also sheds light on even more attractive proteins that will facilitate engineering of novel highly robust reagents.