gebhart/patrepeval huggingface dataset:
MPEG-4 video transmission using distributed TDMA MAC protocol over IEEE 802.15.4 wireless technology (2011)

The issues of green technology nowadays give an inspiration to the researcher to make all the future design to be energy efficient. Medium Access Control (MAC) layer is the most effective layer to provide energy efficient due to its ability to control the physical radio directly. One of the important applications in the future is a video transmission that can be transmitted with low-cost and low power consumption. MPEG-4 is one of the international standards for moving video. MPEG-4 provide better compression and primarily design at low bit rate communication. In order to achieve good quality for video application, the design at MAC layer must be strong. Therefore, to increase the performance of the MPEG-4 in IEEE 802.15.4, in this paper we propose a cross layer design between MAC layer and Application layer. A priority queue will be implemented at MAC scheduling depends on the level of frame important in MPEG-4 format frame. A distributed Time division Multiple Access (TDMA) will be used for MAC protocol to provide reliable data transmission for high priority frame.
Evidence for Ubiquitin-Regulated Nuclear and Subnuclear Trafficking among Paramyxovirinae Matrix Proteins (2015)

The paramyxovirus matrix (M) protein is a molecular scaffold required for viral morphogenesis and budding at the plasma membrane. Transient nuclear residence of some M proteins hints at non-structural roles. However, little is known regarding the mechanisms that regulate the nuclear sojourn. Previously, we found that the nuclear-cytoplasmic trafficking of Nipah virus M (NiV-M) is a prerequisite for budding, and is regulated by a bipartite nuclear localization signal (NLSbp), a leucine-rich nuclear export signal (NES), and monoubiquitination of the K258 residue within the NLSbp itself (NLSbp-lysine). To define whether the sequence determinants of nuclear trafficking identified in NiV-M are common among other Paramyxovirinae M proteins, we generated the homologous NES and NLSbp-lysine mutations in M proteins from the five major Paramyxovirinae genera. Using quantitative 3D confocal microscopy, we determined that the NES and NLSbp-lysine are required for the efficient nuclear export of the M proteins of Nipah virus, Hendra virus, Sendai virus, and Mumps virus. Pharmacological depletion of free ubiquitin or mutation of the conserved NLSbp-lysine to an arginine, which inhibits M ubiquitination, also results in nuclear and nucleolar retention of these M proteins. Recombinant Sendai virus (rSeV-eGFP) bearing the NES or NLSbp-lysine M mutants rescued at similar efficiencies to wild type. However, foci of cells expressing the M mutants displayed marked fusogenicity in contrast to wild type, and infection did not spread. Recombinant Mumps virus (rMuV-eGFP) bearing the homologous mutations showed similar defects in viral morphogenesis. Finally, shotgun proteomics experiments indicated that the interactomes of Paramyxovirinae M proteins are significantly enriched for components of the nuclear pore complex, nuclear transport receptors, and nucleolar proteins. We then synthesize our functional and proteomics data to propose a working model for the ubiquitin-regulated nuclear-cytoplasmic trafficking of cognate paramyxovirus M proteins that show a consistent nuclear trafficking phenotype.
Kinesthetic Sensing for the EMG Controlled "Boston Arm" (1970)

The contribution of a novel cutaneous display of elbow angle to an amputee's ability to position an EMG-controlled externally powered elbow prosthesis was objectively evaluated. Comparisons were made between the amputee's positional control of his conventional mechanical cable-operated elbow and the EMG "Boston Arm"l elbow, with and without angle feedback, in REACHING tasks with vision occluded in all cases and with and without auditory occlusion. MATCHING tasks compared his ability to position the EMG limb to conform with the flexion of his normal (contralateral) elbow. Computer reduction of almost 9000 individual trials and analysis of variance indicated that for the EMG limb the tactile feedback with sound occluded reduced errors by 50 percent. Terminal device load did not significantly affect positioningperformance due to the force proprioception built into the Boston Arm. In comparison with the standard mechanical prosthesis, the EMG limb with feedback achieves virtually identical kinesthetic performance. The display is completely compatible with the EMG control, causes no discomfort to the wearer, and is not significantly degraded by the environmental conditions of the limb socket.
Electrophoretic analysis of human HLA-DR antigens from HLA-DR4 homozygous cell lines: correlation between beta-chain diversity and HLA-D. (1983)

Two-dimensional gel electrophoresis of immunoprecipitated human HLA-DR antigens from cells expressing the HLA-DR4 haplotype shows distinct clustering of beta-chain patterns. Six unique electrophoretic variants were observed among 17 HLA-DR4 homozygous cell lines (HCL) analyzed. These patterns correlate precisely with the HLA-D phenotype of the HCL donor as determined by reactivity in mixed lymphocyte culture. All DR4 HCL that belong to one of the well-defined HLA-D antigen groups (Dw4, Dw10, LD "40", LD "DYT", LD "KT2", or LD "TAS") have identical DR beta-chain patterns; DR4 HCL belonging to different HLA-D antigen groups do not. The concordance of the functional expression in mixed lymphocyte culture of a specific D phenotype with a distinct DR beta-chain pattern on gel analysis provides a direct structural basis for understanding the genetic control of HLA-D polymorphisms; HLA-D specificities as revealed by T-cell recognition in mixed lymphocyte culture thus might be accounted for by DR beta-chain polymorphisms. The extent of this beta-chain diversity within a single DR haplotype may aid in understanding variations in Ia-regulated functions, such as Ir gene control and certain disease susceptibilities.
Preparation of PbTiO<sub>3</sub> Thin Films by Screen Printing Method (1994)

PbTiO 3 thin films were obtained by the screen printing method on Au bottom electrodes using Si(100) substrates. The screen-printable paste was synthesized from the Pb–Ti complex alkoxide and abietic acid. The optimum conditions of amount of PbO content in the paste and annealing temperature were investigated to prepare the ferroelectric thin film. The remanent polarization and coercive field of this thin film were 8 µ C/cm 2 and 110 kV/cm, respectively. Pyroelectric coefficient was 0.67× 10 -8 (C/cm 2 ·K) after poling.
Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP. (1996)

LNCaP cells, derived from an androgen-sensitive cell line widely employed as an in vitro model of human prostate cancer, have been shown to express activin receptors. Activin is a local regulator of cellular growth, appears to play a key role in mesoderm induction and differentiation during development, and has been implicated in gonadal tumorigenesis. Follistatin, a monomeric glycoprotein that specifically binds and neutralizes activin, is often coexpressed with activin and, thus, modulates the autocrine/paracrine biological activity of this potent growth factor. We tested the hypothesis that LNCaP growth is modulated by the activin/follistatin system. Recombinant human activin A inhibited [3H]thymidine incorporation in a dose-dependent fashion with an ED50 of approximately 0.43 +/- 0.3 nM. Activin (0.1-3 nM) also inhibited dihydrotestosterone (DHT)-stimulated [3H]thymidine incorporation in LNCaP cells. Similarly, recombinant human inhibin A inhibited LNCaP proliferation, but was only 1/100th as potent as activin. Furthermore, activin (3 nM) induced a 3-fold increase in the extent of labeling of low mol wt DNA fragments typical of apoptosis. Activin-induced apoptosis was also indicated by an increase in the number of cells with reduced DNA content, as measured by flow cytometry of activin-treated cells. Both activin-mediated inhibition of cell proliferation and induction of apoptosis could be completely blocked by recombinant human follistatin. Based upon these results using an in vitro model, we speculate that activin functions locally to oppose androgen-driven cell proliferation and, thus, is a key factor controlling prostate growth. Reduced activin biosynthesis, increased follistatin secretion, or signaling defects in the activin receptor system should be further investigated in future studies as potential mechanisms underlying enhanced androgen-independent growth of human prostate cancer cells.
Electrical power systems quality (1996)

Electrical Power Systems Quality, Third Edition, is a complete, accessible, and up-to-date guide to identifying and preventing the causes of power quality problems. The information is presented without heavy-duty equations, making it practical and easily readable for utility engineers, industrial engineers, technicians, and equipment designers. This in-depth resource addresses the essentials of power quality and tested methods to improve compatibility among the power system, customer equipment, and processes.Coverage includes:• Standard terms and definitions for power quality phenomena• Protecting against voltage sags and interruptions• Harmonic phenomena and dealing with harmonic distortion• Transient overvoltages• Long-duration voltage variations• Benchmarking power quality• International Electrotechnical Commission (IEC) and Institute of Electrical and Electronics Engineers (IEEE) standards• Maintaining power quality in distributed generation systems• Common wiring and grounding problems, along with solutions• Site surveys and power quality monitoring
U.S. Climate Tilts Toward the Greenhouse (1995)

Thomas Karl and his colleagues at the National Climatic Data Center in NC have found indications that the US climate has turned toward a greenhouse regime in the past 15 years. By combining data on summer droughts, wet winters, drenching rainstorms, and other weather extreams, expected to grow more common in a warmer climate, the researchers have developed a Greenhouse Climate Response Index. This short article describes the Index and comments of other scientists about its ability to predict Greenhouse responses.
Role of Fibroblast Growth Factors and Their Receptors in Pancreatic Cancer and Chronic Pancreatitis (1998)

The fibroblast growth factor (FGF) family is a group of homologous heparin-binding polypeptides that has been implicated in a variety of human neoplasms and presently includes 14 members. FGF signaling is mediated by a dual-receptor system, consisting of four high-affinity tyrosine kinase receptors, termed fibroblast growth factor receptors (FGFRs), and of low-affinity heparan sulfate proteoglycan receptors that enhance ligand presentation to the FGFRs. Several FGFs, including FGF-1, -2, -3, -4, -5, -6, and -7, and several FGFR variants, among them the 2 immunoglobulin-like form and the IIIc splice variant of FGFR-1 and the keratinocyte growth factor receptor, a splice variant of FGFR-2, are expressed in human pancreatic cancer cell lines and are overexpressed in human pancreatic cancers or in the pancreas of chronic pancreatitis and, therefore, may play important roles in the pathobiology of these pancreatic diseases. This review summarizes the current information on the involvement of the FGF family and their receptors in human pancreatic cancer and chronic pancreatitis.
Image classification based on region of interest detection (2015)

For image classification tasks, the region containing object which plays a decisive role is indefinite in both position and scale. In this case, it does not seem quite appropriate to use the spatial pyramid matching (SPM) approach directly. In this paper, we describe an approach for handling this problem based on region of interest (ROI) detection. It verifies the feasibility of using a state-of-the-art object detection algorithm to separate foreground and background for image classification. It first makes use of an object detection algorithm to separate an image into object and scene regions, and then constructs spatial histogram features for them separately based on SPM. Moreover, the detection score is used to rescore. Our contributions include: i) verify the feasibility of using a state-of-the-art object detection algorithm to separate foreground and background used for image classification; ii) a simple method, called <i>coarse object alignment matching</i>, is proposed for constructing histogram using the foreground and background provided by object localization. Experimental results demonstrate an obvious superiority of our approach over the standard SPM method, and it also outperforms many state-of-the-art methods for several categories.
Generation of a Uracil Auxotroph Strain of the Probiotic Yeast Saccharomyces boulardii as a Host for the Recombinant Protein Production. (2013)

A uracil auxotroph mutant of the probiotic yeast, S. boulardii, was generated and characterized. This auxotroph strain may have potential applications in the production and delivery of the recombinant pharmacuetics into the intestinal lumen.
Numerical modeling of altocumulus cloud layers (1998)

Altocumulus (Ac) clouds are predominately water clouds and typically less than several hundred meters thick. Ac cloud heights are mid-level, from 2 to 8 km. Ac clouds cover large portions of the Earth and play an important role in the Earth&apos;s energy budget through their e#ects on solar and infrared radiation. A two-dimensional cloud resolving model (CRM) and a one-dimensional turbulent closure model (TCM) are used to study Ac clouds with idealized initial conditions. An elevated mixed layer model (MLM) is developed and the results for the MLM are compared with results for CRM. The impacts of large-scale vertical motion, and solar and IR radiation, the utility of the TCM, the mixed layer characteristics and circulation of Ac layers, the turbulent kinetic energy (TKE) budget, and e#ects of relative humidify (RH) above the cloud are studied with a series of numerical simulations using the CRM and TCM. The results show that weak large-scale vertical motion may allow for a long lifetime of...
Performance comparison of signal strength and signal quality based Inter-RAT MRO (2012)

The Long Term Evolution (LTE) network is currently being deployed on top of the legacy radio access technologies (RATs) such as the second generation (2G) or third generation (3G) mobile networks. Inter-RAT mobility robustness optimization (MRO) is one of the most important use cases for self-organizing network (SON). Unlike the manual optimization methods, an inter-RAT MRO algorithm adjusts the handover thresholds of each cell in autonomous and automatic manner. An inter-RAT handover is triggered when a measurement event is received from a user equipment (UE). The measurement event can rely on different measurement quantities, namely either signal strength (SS) or signal quality (SQ), where SQ takes the interference experienced by the UE into account. This paper investigates the sensitivity of the two measurement quantities on the behavior of the inter-RAT MRO algorithm in terms of optimization performance. Results have shown that SS is a more robust measurement quantity than SQ as it yields lower numbers of inter-RAT handovers and mobility failure events. Moreover, inter-RAT MRO is needed to achieve the best performance in each cell for both SS and SQ measurement quantities even though the optimization range of the handover thresholds is relatively small for the latter case.
Observation on the effect of continuous nursing intervention on improving the quality of life of elderly patients with lower extremity arterial disease (2017)

Objective
To observe the effect of continuous nursing intervention on improving the quality of life of elderly patients with lower extremity arterial disease.


Methods
Elderly patients with lower extremity arterial disease treated in our hospital from October 2013 to October 2015 were selected as the observation object, and were divided into the intervention group and control group according to the random number table method, 50 cases in each group.The control group was given the routine nursing, while the intervention group was given the continuous nursing intervention.The differences in terms of pain, mental state and quality of life were compared between the two groups before and after the intervention.


Results
There was no significant difference in terms of VAS scores of the two groups before the intervention, and the VAS scores of the two groups were both lower than that before the intervention, and the VAS scores of the intervention group was decreased more significantly(P<0.05). There was no significant difference in terms of SAS and SDS scores between the two groups before the intervention.The SAS and SDS scores of the two groups were both lower than that before the intervention, and the SAS and SDS scores of the the intervention group was decreased more significantly(P<0.05). There was no significant difference in terms of quality of life of the two groups before the intervention.The scores of quality of life of the two groups were both higher than that before treatment, and the scores of quality of life of the intervention group was significantly higher(P<0.05).


Conclusion
The continuous nursing intervention can improve the psychological status and improve the quality of life of elderly patients with lower extremity arterial disease.


Key words: 
Continuous care; Artery; Quality of life; Pain
Mouse spinal cord in cell culture. I. Morphology and intrinsic neuronal electrophysiologic properties (1977)

1. Reliable methods for establishing fetal mouse spinal cord (SC) and dorsal root ganglion (DRG) cells in long term (greater than 1 mo) dissociated cell cultures are described. These cells have been studied by morphologic and intracellular electrophysiologic techniques. 2. Cells studied electrophysiologically can be relocated after preparation for electron microscopy and examined in thin sections. The electron microscope shows that the surface membranes of these cells were directly accessible to the culture medium. The surfaces of SC cells were studded with synaptic boutons, whereas the DRG cell surfaces generally had none. 3. Current-voltage relationships and linear electrotonic properties of the neurons are described. Delayed and anomalous rectification were seen in both cell types. The length of SC cell dendrites was about one characteristic electrotonic length, while little or no contribution of the relatively sparse DRG cell processes was seen in the transient responses of the DRG cells. 4. Postspike and posttetanic hyperpolarizations in DRG cells were due to a surface membrane conductance increase; this was probably primarily an increase in K+ conductance. Post-activation hyperpolarization in SC cells was primarily due to activation of an electrogenic Na+ pump.
Generative Adversarial Learning for Machine Learning empowered Self Organizing 5G Networks (2019)

In the wake of diversity of service requirements and increasing push for extreme efficiency, adaptability propelled by machine learning (ML) a.k.a self organizing networks (SON) is emerging as an inevitable design feature for future mobile 5G networks. The implementation of SON with ML as a foundation requires significant amounts of real labeled sample data for the networks to train on, with high correlation between the amount of sample data and the effectiveness of the SON algorithm. As generally real labeled data is scarce therefore it can become bottleneck for ML empowered SON for unleashing their true potential. In this work, we propose a method of expanding these sample data sets using Generative Adversarial Networks (GANs), which are based on two interconnected deep artificial neural networks. This method is an alternative to taking more data to expand the sample set, preferred in cases where taking more data is not simple, feasible, or efficient. We demonstrate how the method can generate large amounts of realistic synthetic data, utilizing the GAN's ability of generation and discrimination, able to be easily added to the sample set. This method is, as an example, implemented with Call Data Records (CDRs) containing the start hour of a call and the duration of the call, in minutes taken from a real mobile operator. Results show that the method can be used with a relatively small sample set and little information about the statistics of the true CDRs and still make accurate synthetic ones.
Coordinated learning to support resource management in computational grids (2003)

Managing resources in large scale distributed systems is an important concern for both peer-2-peer and computational grid systems, and is a complex and time sensitive process. Although existing peer-2-peer systems are divided into those that support computation (CPU) sharing or data sharing, users in a computational grid generally need to share both. Identifying which resources to select is important to guarantee reasonable execution time and cost to a given user or group of users. We provide first a description of a framework to support learning in the context a community of interacting peers, and show how this can be used to support resource sharing in computational grids.
Hepatocyte nuclear factor 1 alpha activates promoter 1 of the human insulin-like growth factor I gene via two distinct binding sites. (1995)

Expression of the human insulin-like growth factor I (hIGF-I) gene is regulated in a tissue- and developmental stage-specific manner. The hIGF-I gene has two promoters, P1 and P2. P1 is the more active promoter by far in adult liver, the main endocrine source of IGF-I. Recently, we described the involvement of the CAAT/enhancer binding protein family of liver-enriched transcription factors in the regulation of the expression of IGF-I in adult liver. In this study we report on the role of another family of liver-enriched transcription factors in the regulation of IGF-I expression. Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) is shown to transactivate IGF-I P1 in transient transfection experiments performed in Hep3B cells. Bandshift experiments reveal that two distinct regions in P1, located 119 and 282 nucleotides upstream of the transcription start site, can bind HNF-1 alpha with relatively high affinity. Both HNF-1-binding sites are evolutionary well conserved, emphasizing the importance of HNF-1 in the regulation of the IGF-I gene expression. Mutational analysis of the binding sites indicates that both sites are essential for maximal stimulation of P1 by HNF-1 alpha, although the largest contribution stems from the more downstream of the two HNF-1-binding sites. The latter site completely overlaps the previously described CAAT/enhancer binding protein binding site in P1. The colocalization of the binding sites, to which binding of the respective factors seems to be mutually exclusive, is suggestive of a regulatory hotspot to which members of different transcription factor families may bind depending on developmental stage and nutritional status.