gebhart/patrepeval huggingface dataset:
Feature Article—Interior Point Methods for Linear Programming: Computational State of the Art (1994)

A survey of the significant developments in the field of interior point methods for linear programming is presented, beginning with Karmarkar's projective algorithm and concentrating on the many variants that can be derived from logarithmic barrier methods. Full implementation details of the primal-dual predictor-corrector code OB1 are given, including preprocessing, matrix orderings, and matrix factorization techniques. A computational comparison of OB1 with a state-of-the-art simplex code using eight large models is given. In addition, computational results are presented where OB1 is used to solve two very large models that have never been solved by any simplex code INFORMS Journal on Computing, ISSN 1091-9856, was published as ORSA Journal on Computing from 1989 to 1995 under ISSN 0899-1499.
The Internal Market (2010)

This chapter provides an overview of what the internal market is, and the current debates about what it should be. It provides background and context to the chapters on free movement which follow. The chapter is organised as follows.
Lactational changes of fatty acids and fat-soluble antioxidants in human milk from healthy Chinese mothers (2020)

Human milk fat is specially tailored to supply the developing infant with adequate and balanced nutrients. The present study aimed to quantify the composition of fatty acids, tocopherols and carotenoids in human milk, with special emphasis on the lactational changes. Colostrum, transitional and mature milk samples were collected longitudinally from the same forty-two healthy, well-nourished Chinese mothers. Fatty acids were quantified by GC with carotenoids (carotenes and xanthophylls) and tocopherols (α-, γ-tocopherol) determined by HPLC. Total fatty acid (TFA) content increased from 15·09 g/l in colostrum to 32·57 g/l in mature milk with the percentages of DHA and arachidonic acid (ARA) decreased. The ratio of n-6:n-3 PUFA and ARA:DHA remained constant during lactation at about 11:1 and 1·3:1, respectively. Both α-tocopherol and γ-tocopherol decreased over lactation with the ratio of α-:γ-tocopherol declined significantly from 7·21:1 to 4·21:1 (P < 0·001). Carotenoids all dropped from colostrum to mature milk as the less polar carotenes dropped by 88·67 %, while xanthophylls only dropped by 35·92 %. Lutein was predominated in both transitional and mature milk carotenoids (51·64-52·49 %), while colostrum carotenoids were mainly composed of lycopene (32·83 %) and β-carotene (30·78 %). The concentrations of tocopherols and xanthophylls but not carotenes were positively associated with TFA content in milk. These results suggested that colostrum and mature milk contained divergent lipid profiles and selective transfer mechanisms related to polarity might be involved. The present outcomes provide new insights for future breast-feeding studies, which also add in scientific evidences for the design of both initial and follow-on infant formulas.
The Secondary Prevention of Coronary Artery Disease (1997)

Randomized clinical trials demonstrate the efficacy of medical secondary prevention in coronary disease patients. The magnitude of risk reduction with exercise, diet, lipid modification, and smoking cessation is similar to other medical therapies for coronary disease such as aspirin, beta blockers, as well as coronary bypass surgery, (Table VI) In contrast to these therapies, however, secondary prevention stabilizes angiographic progression in about 50% of patients and induces regression in about 25% of patients. Both symptoms and perceived quality of life also are beneficially altered by secondary prevention programs, although possibly not by the magnitude reported for bypass surgery. These clinical trial results have led the American Heart Association, and the American College of Cardiology to strongly endorse secondary prevention. A reasonable projection based on these clinical trial data is that widespread use of these recommendations in the 12 million established coronary disease patients would significantly reduce coronary mortality and morbidity.
Light-weight bounds checking (2012)

Memory errors in C and C++ programs continue to be one of the dominant sources of security problems, accounting for over a third of the high severity vulnerabilities reported in 2011. Wide-spread deployment of defenses such as address-space layout randomization (ASLR) have made memory exploit development more difficult, but recent trends indicate that attacks are evolving to overcome this defense. Techniques for systematic detection and blocking of memory errors can provide more comprehensive protection that can stand up to skilled adversaries, but unfortunately, these techniques introduce much higher overheads and provide significantly less compatibility than ASLR. We propose a new memory error detection technique that explores a part of the design space that trades off some ability to detect bounds errors in order to obtain good performance and excellent backwards compatibility. On the SPECINT 2000 benchmark, the runtime overheads of our technique is about half of that reported by the fastest previous bounds-checking technique. On the compatibility front, our technique has been tested on over 7 million lines of code, which is much larger than that reported for previous bounds-checking techniques.
Quasi-Cyclic Low-Density Parity-Check Codes in the McEliece Cryptosystem (2007)

In this paper, a new variant of the McEliece cryptosystem, based on quasi-cyclic low-density parity-check (QC-LDPC) codes, is studied. In principle, such codes can substitute Goppa codes, originally used by McEliece; their adoption, however, is subject to cryptanalytic evaluation to ensure sufficient system robustness. The authors conclude that some families of QC-LDPC codes, based on circulant permutation matrices, are inapplicable in this context, due to security issues, whilst other codes, based on the "difference families" approach, can be able to ensure a good level of security against intrusions, even if very large lengths are needed.
Synthesis, Molecular Structure, and Reactivity of Organolanthanide Fluoride Complexes, [{(Me<sub>3</sub>Si)<sub>2</sub>C<sub>5</sub>H<sub>3</sub>}<sub>2</sub>Ln(μ-F)]<sub>2</sub>(Ln = La, Nd, Sm, Gd) and [(C<sub>5</sub>H<sub>5</sub>)<sub>2</sub>Ln(μ-F)(THF)]<sub>2</sub>(Ln = Y, Yb) (1998)

Treatment of Me3NHF with 1 equiv of [(Me3Si)2C5H3]3Ln or (C5H5)3Ln in THF gave [{(Me3Si)2C5H3}2LnF]2 (Ln = La (1), Nd (2), Sm (3), Gd (4)) or [(C5H5)2LnF(THF)]2 (Ln = Y (5), Yb (6)) in moderate to good yield. All of them were fully characterized by elemental analyses, spectroscopy, and X-ray analyses. Compound 3 reacted with Na, AlCl3, (C6H5)3SiOH, and 2,6-Pri2C6H3OH to form [(Me3Si)2C5H3]2Sm(THF), [{(Me3Si)2C5H3}2SmCl]2, [(C6H5)3SiO]3Sm(THF)3 (7), and [2,6-Pri2C6H3O]3Sm(THF)3 (8), respectively. The molecular structures of [{(Me3Si)2C5H3}2SmCl]2, 7, and 8 were confirmed by X-ray diffraction study. The 3/NaH system can convert C6H5Br into C6H6 in 32% yield.
Statistical Applications in Genetics and Molecular Biology (2009)

In this paper, we address the problem of detecting outlier samples with highly different expression patterns in microarray data. Although outliers are not common, they appear even in widely used benchmark data sets and can negatively affect microarray data analysis. It is important to identify outliers in order to explore underlying experimental or biological problems and remove erroneous data. We propose an outlier detection method based on principal component analysis (PCA) and robust estimation of Mahalanobis distances that is fully automatic. We demonstrate that our outlier detection method identifies biologically significant outliers with high accuracy and that outlier removal improves the prediction accuracy of classifiers. Our outlier detection method is closely related to existing robust PCA methods, so we compare our outlier detection method to a prominent robust PCA method. ∗The authors would like to thank the anonymous reviewers, whose comments helped improve the manuscript.
The quantum transmitting boundary method (1990)

A numerical algorithm for the solution of the two-dimensional effective mass Schrödinger equation for current-carrying states is developed. Boundary conditions appropriate for such states are developed and a solution algorithm constructed that is based on the finite element method. The utility of the technique is illustrated by solving problems relevant to submicron semiconductor quantum device structures.
Realtime Indoor Workout Analysis Using Machine Learning & Computer Vision (2019)

These days there are thousands of workout videos available on the internet. Samsung Health<sup>2</sup> [1] provides a dedicated section called programs containing short workout videos for various exercises. The goal is to assist people perform these workouts independently on their own. A common observation is that even people who visit gym regularly find it difficult to perform all steps (body pose alignments) in a workout accurately. Continuously doing an exercise incorrectly may eventually cause severe long term injuries. To help solve this problem and provide assistance in form of a visual feedback while performing a workout, we propose a system to analyze user's body posture during a workout and compare it to a professional's reference workout. We represent human body as a collection of limbs and analyze angle between limb pairs to detect errors and provide corrective action to the user. Our system builds on the latest advancements using deep learning for human body pose estimation. We use techniques for time series data alignment like DTW [2] (Dynamic Time Warping) along with optical flow tracking to synchronize user/reference videos. We are able to detect and locate errors in user's activity (pose) very effectively based on some threshold deviation between the limb angles. The system in future can be extended to be used by physicians to monitor patient's recovery following an injury.
Universal accessibility as a multimodal design issue (2007)

Creating adaptable solutions to address diverse users and situations.
Effects of varying the progesterone content of CIDR intravaginal devices and multiple CIDR treatments on plasma hormone concentrations and residual hormone content (1990)

Two trials were conducted to study factors which influenced the amount of progesterone (P4) remaining in a CIDR intravaginal device used for a treatment period of 15 days and the associated plasma P4 concentrations. In the first trial, the initial P4 content of these devices was varied fromOto2.67gP4. Inthesecondtrial,animals weretmatedwitheitheroneorthrcedetices whichhadbeenmouldedtocontainthesameamount of P4 (l.gg/device). Increasing the initial P4 ccntent of a device increased plasma P4 concentrations, but at a diminishing rate so that devices containiig 1.86 g P4 maintained similar levels of plasma P4 to devices ccntaining 2.67 g P4 (2.48 vs 2.63 ng/ml). This was associated with a quadratic relationship in the residual P4 content in the used devices. Using three devices per animal trebled plasma P4 concentrations and did not alter residual P4 content. These results indicated that P4 release is influenced more by device characteristics than by animal variation.
TAN-999 and TAN-1030A, new indolocarbazole alkaloids with macrophage-activating properties. (1989)

Two new indolocarbazole alkaloids, TAN-999 and TAN-1030A, were isolated from culture broths of Nocardiopsis dassonvillei C-71425 and Streptomyces sp. C-71799, respectively. Their structures were elucidated on the basis of their reactions, spectroscopic analyses and in particular, comparison of spectral data with that of staurosporine. These metabolites induced spreading of a murine macrophage cell line, Mm 1. They also augmented the phagocytic activity, Fc gamma receptor expression and beta-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. When proteose-peptone elicited peritoneal macrophages from mice were incubated with these metabolites for 2 days, the phagocytosis-dependent respiratory burst of these cells was enhanced. Similar enhancement was also observed when the peritoneal macrophages in mice were modulated by intraperitoneal administration of these metabolites. These results reveal that TAN-999 and TAN-1030A can activate macrophage functions in mice.
Absolute stereochemistry of cladospolide A, a phytotoxic macrolide from Cladosporium cladosporioides. (1985)

A (I), C12H20O4, is a phytotoxic substance produced by Cladosporium cladosporioides FI-1 13 and its planar structure has been established as ()-4,5-dihydroxy-2dodecen-l l-olide.1'2)
A high-throughput VLSI architecture for linear turbo equalization (2004)

Turbo equalization dramatically improves bit error rate (BER) over separate equalization and decoding receivers. However, turbo equalization has low throughput due to iterative processing where a soft-input soft-output (SISO) equalizer or decoder cannot begin before the end of the previous SISO decoding iteration. In this paper, we propose a high-throughput VLSI architecture for linear turbo equalizers via rescheduling the soft information updates on a factor graph. The proposed method enables SISO equalizers and decoders to run concurrently thereby reducing the processing time. Thus, the proposed architecture increases throughput by 40%-75% without any loss in BER.
Elongation Factor Tu Mutants Expand Amino Acid Tolerance of Protein Biosynthesis System (2007)

Nonnatural amino acids have been introduced into proteins using expanded protein biosynthesis systems. However, some nonnatural amino acids, especially those containing large aromatic groups, are not efficiently incorporated into proteins. Reduced binding efficiency of aminoacylated tRNAs to elongation factor Tu (EF-Tu) is likely to limit incorporation of large amino acids. Our previous studies suggested that tRNAs carrying large nonnatural amino acids are bound less tightly to EF-Tu than natural amino acids. To expand the availability of nonnatural mutagenesis, EF-Tu from the E. coli translation system was improved to accept such large amino acids. We synthesized EF-Tu mutants, in which the binding pocket of the aminoacyl moiety of aminoacyl-tRNA was enlarged. L-1-Pyrenylalanine, L-2-pyrenylalanine, and DL-2-anthraquinonylalanine, which are hardly or only slightly incorporated with the wild-type EF-Tu, were successfully incorporated into a protein using these EF-Tu mutants.
Oral manifestations of congenital neutropenia or Kostmann syndrome (2002)

Infantile congenital agranulocytosis or Kostmann syndrome is a rare hereditary kind of severe neutropenia. The typical symptoms, which appear since the first days of life, are abscesses located on various parts of the body: ear, cutis, lung and oral cavity. These abscesses are due to an almost total disimmunity typical of the neutropenia. The aim of this article is to describe the most typical signs of this pathology in the oral cavity, reporting a case observed in our department in Florence, Italy. On the basis of the personally observed case and of the review of the literature, it is possible to consider, as a characteristic finding in Kostmann syndrome, a typical very serious periodontal pathology, which is similar to the prepubertal periodontitis in deciduous dentition. At the age of 19 years the patient showed a dramatic compromise of the masticatory function. It is obvious that the lack of response of the host can obstruct the interaction between the host and the microbic flora, because the lack of neutrophils increases the susceptibility of the patient to every kind of infection, even to periodontitis. A periodontal prophylaxis, since the very first observations, followed by a rigorous maintenance with frequent and regular professional hygienic treatments could be effective in controlling the effects of periodontal disease and could reduce the tragic evolution. We need to recognise that it could be hard to monitor the oral situation correctly in these patients, as they have a continuously poor systemic condition. Finally in these cases the rehabilitative therapy is very problematical.
Self-compression of intense optical pulses and the filamentary regime of nonlinear optics (2011)

Diese Arbeit beschäftigt sich mit Femtosekunden-Filamenten in dispersiven, transparenten Medien. Die Erzeugung optischer Femtosekunden-Impulse durch Selbstkompression in Edelgasen wird unter theoretischen und experimentellen Aspekt behandelt, wobei die zugrundeliegenden physikalischen Mechanismen aufgezeigt werden. Dazu werden numerische Simulationen hochintensiver Femtosekunden-Impulse in Edelgasen durchgeführt, und eine analytische Beschreibung der Selbstkompression wird entwickelt. Im experimentellen Teil der Arbeit wird eine bisher nur theoretisch vorhergesagte Selbstheilungseigenschaft des zeitlichen Impulsverlaufs in Femtosekunden-Filamenten nachgewiesen. Es wird gezeigt, dass die zeitliche Impulsform stabil gegenüber einer adiabatisch einsetzenden, temporären Zunahme von Dispersion und Nichtlinearität um jeweils drei Größenordnungen ist, wie sie beim Durchgang durch das Austrittsfenster einer gasgefüllten Zelle auftritt. Die optische Feldstärke in Filamenten ist vergleichbar mit inneratomaren Bindungskräften. Bei derart hohen Intensitäten treten hochgradig nichtlineare Effekte wie Multiphoton- oder Tunnelionisation auf. Neuere experimentelle Befunde deuten an, dass die Sättigung des optischen Kerr-Effekts eine entscheidende Rolle in Filamenten spielt, im Gegensatz zur bisherigen Annahme der Sättigung der optischen Nichtlinearität durch freie Ladungsträger. Dieser Befund wird derzeit in der Literatur kontrovers diskutiert. Im Rahmen dieser Arbeit wird ein unabhängiger theoretischer Ansatz verfolgt, um Beiträge hoher Ordnungen zum optisch-optischen Kerr-Effekt aus einer Kramers-Kronig Transformation des Multiphoton-Absorptionskoeffizienten abzuschätzen. Auschließlich ausgehend von physikalischen Grundprinzipien sowie einiger moderater Näherungen stützen diese Ergebnisse ein kürzlich vorgeschlagenes Modell, welches relevante Beiträge höherer Ordnung zum optisch-optischen Kerr-Effekt vorhersagt.
Synthesis of a Vicinal Tricarbonyl Amide Derivative of <scp>l</scp>-Phenylalanine (1996)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSynthesis of a Vicinal Tricarbonyl Amide Derivative of l-PhenylalanineJack H. Lai, Ha Pham, and David G. HangauerView Author Information Department of Medicinal Chemistry, School of Pharmacy, State University of New York at Buffalo, Buffalo, New York 14260 Cite this: J. Org. Chem. 1996, 61, 5, 1872–1874Publication Date (Web):March 8, 1996Publication History Received16 October 1995Published online8 March 1996Published inissue 1 January 1996https://doi.org/10.1021/jo951855aCopyright © 1996 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views517Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (135 KB) Get e-AlertsSUBJECTS:Carbonyls,Monomers,Peptides and proteins,Solvates Get e-Alerts
Macrophage migration inhibitory factor is essential for allergic asthma but not for Th2 differentiation (2007)

Macrophage migration inhibitory factor (MIF) is increased in asthmatic patients and plays a critical role in the pathogenesis of asthma. We show here that mice lacking MIF failed to develop airway hyper-responsiveness (AHR), tissue eosinophilia, and mucus metaplasia. Analysis of the bronchoalveolar fluids revealed a substantial reduction of IL-13, eotaxin and cysteinyl-leukotrienes. The lack of these cardinal features of asthma in MIF(-/-) mice occurs regardless of high concentrations of IL-4 in the lung and OVA-specific IgE in the serum. Antigen-specific lymphocyte proliferation and IL-13 production were similarly increased in the draining lymph nodes of OVA-immunized and challenged MIF(-/-) mice compared to WT, but were reduced in the spleen of MIF(-/-), thus indicating differential roles of MIF in these compartments. Stimulation of naive CD4(+) cells with anti-CD3 antibody demonstrated that MIF(-/-) cells produced increased amounts of IFN-gamma and IL-4 compared to WT CD4(+) cells. Finally, treatment of sensitized BALB/c mice with neutralizing anti-MIF antibody abrogated the development of ARH and airway inflammation without affecting the production of Th2 cytokines or IgE. The present study demonstrates that MIF is required for allergic inflammation, adding important elements to our knowledge of asthma pathogenesis and suggesting that neutralization of MIF might be of therapeutic value in asthma.
A Fluorinated Organic-Silica Film with Extremely Low Dielectric Constant (1999)

A fluorinated organic-silica film was prepared by quasi hydrogen-free chemical-vapor deposition. The content of methyl groups and fluorine atoms incorporated in the film were as much as 43% and 9% of that of Si. The film had good insulating characteristics with the dielectric constant, k , of as low as 2.5 even under as-prepared conditions. They were improved by vacuum annealing; k was 2.1 and the low-field resistivity was 10 16 Ωcm after annealing at 500°C. It was confirmed that the film prepared at 200°C was stable for more than 20 days in the air.
VISAPP 2015.pdf (2016)

Accepted for Visapp 2015.
Rolph Schwarzenberger (1936–1992) - an appreciation (1993)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Functional Consequences of Interactions between Human Neutrophils and ATP, ATPγS, and Adenosine<sup>a</sup> (1990)

Peer Reviewed