gebhart/patrepeval huggingface dataset:
A Study of the Scope, Limitations and Kinetics of the Siliconization of Triarylamines Using Tris(pentafluorophenyl)borane Catalysis (2012)

Piers-Rubinsztajn (P-R) conditions, involving catalysis by tris(pentafluorophenyl)borane, were applied to siliconize triarylamines. A phenylated linear methylhydrosiloxane copolymer was utilized to create a hydrolytically-stable composite with promising optical, electrochemical and thermal properties. However, the reaction was highly exothermic, had rapid uncontrollable kinetics and produced methane as a byproduct; problematic characteristics for larger scale syntheses. Thereafter, triarylamines with bulkier substituents were studied to determine whether the kinetics could be slowed and a less volatile byproduct created. The rate of conversion was retarded significantly as expected, but not all derivatives reacted quantitatively in ambient conditions. Finally, P-R conditions were applied to methylhydrosiloxane-dimethylsiloxane copolymers. Gelation in air upon extended reaction time was effectively avoided by âfinishingâ excess Si-H sites using anisole. The result was the preparation of composites with up to 61 wt % arylamine content, which are expected to have significant applications as cost-effective flexible hole transport layers in organic electronic devices.
Molecular beam epitaxial growth of InAs on a TlBaCaCuO superconducting film (1990)

Results of growth of InAs on a superconducting TlCaBaCuO (2-1-2-2) thin film are reported. The InAs was grown by molecular beam migration-enhanced epitaxy at a substrate temperature of 250 °C. The Tc(zero) of the Tl film before and after InAs deposition was 106 and 100 K, respectively. X-ray diffraction and reflection electron microscopy studies showed the InAs to be polycrystalline, having grains in the 300 Å size range. This is the first report of deposition of a III-V semiconductor on superconductor, without significant degradation of Tc.
Urinary glycolate measured by use of (S)-2-hydroxy-acid oxidase. (1985)

Glycolate can be determined in urine by using (S)-2-hydroxy-acid oxidase (EC 1.1.3.15; formerly called "glycolate oxidase"), either immobilized in a continuous-flow system or in a semiautomated procedure for the centrifugal analyzer. In the presence of peroxidase (EC 1.11.1.7), the hydrogen peroxide formed from glycolate is detected by use of a peroxide indicator reaction. Before the analysis, urine must be treated with charcoal to remove reducing substances such as ascorbic acid, which interfere with the assay by decreasing the color of the indicator reaction. Lactate also interferes with the determination of glycolate because it also is a substrate for this oxidase; thus a correction has to be made for the lactate content of urine. The system with (S)-2-hydroxy-acid oxidase immobilized to the inner surface of nylon tubing is accurate, precise, and sensitive but unsuitable for routine use because, even immobilized, the oxidase is unstable and can only be used for 12 days. We have used the semiautomated assay routinely: it has a mean analytical recovery of 96% (SD 4.2%), a within-batch CV less than 2%, and a between-batch CV less than 5%. The normal reference interval for urinary excretion of glycolate so measured is 0.13 to 1.31 mmol per day (n = 55).
Cloning the spoT gene of Escherichia coli: identification of the spoT gene product (1979)

We have isolated five specialized transducing lambda bacteriophages (lambda dpyrE spoT) carrying the pyrE and spoT genes of Escherichia coli. A fragment from one of these phages was used as the source of DNA to clone the spoT and pyrE genes on a multicopy plasmid, pBR322. Insertions and deletions in this plasmid were obtained. These plasmids were used to transform a minicell-producing strain, and the gene products synthesized were determined. Our experiments demonstrate that the spoT and pyrE genes are separated by about 4 magadaltons and suggest that the spoT gene product is a protein whose molecular weight is 80,000. The strain in which the spoT+ allele is carried on a plasmid produced nine times more spoT gene activity than a normal spoT+ strain when assayed in crude extracts. This strain was used to prepare partially purified gene product, guanosine 5'-diphosphate, 3'-diphosphate pyrophosphatase. The enzyme has the following characteristics. (i) It hydrolyzes pyrophosphate from the 5'-pyrophosphate of guanosine 5'-diphosphate, 3'-diphosphate, yielding GDP and pyrophosphate. (ii) Its activity is strongly stimulated by Mn2+ and slightly stimulated by salt. (iii) Its activity is inhibited by uncharged tRNA. There are also two additional activities in the cell extract which degrade guanosine in 5'-diphosphate, 3'-diphosphate in vitro but which are not specified by the spoT gene.
Robust replica correlation-based symbol synchronisation in OFDM systems (2008)

A simple symbol timing synchronisation (STS) scheme is proposed, based on replica correlation robust to frequency offset in orthogonal frequency division multiplexing systems. The proposed scheme applies a sequence and its modified sequence to total feasible frequency resources used in STS. A comparison is made with the current long-term evolution scheme.
Improved glioblastoma treatment with Ad5/35 fiber chimeric conditionally replicating adenoviruses (2007)

Adenovirus type 5 (Ad5)-based vectors have been used in clinical trials for glioblastoma treatment, but the capacity of Ad5 to infect human glioma cells was questioned. Seeking to improve the adenovirus transduction, we tested four Ad5-based vectors differing only in their fiber gene on permanent and short-term cultures of glioblastoma cells. A wild-type fiber Ad5 vector (Ad5.Luc) was compared to an RGD integrin-binding motif-containing fiber adenovirus (AdlucRGD) and the two fiber chimeras Ad5/3 and Ad5/35, with vector binding redirected to the Ad3 or Ad35 receptor, respectively. Compared to Ad5, the transduction of the tested short-term glioblastoma cultures with the vector Ad5/35.Luc, AdlucRGD and Ad5/3.Luc was enhanced by approximately 72%, approximately 13% and approximately 2%, respectively. To limit adenovirus spread, we aimed to develop conditionally replicative Ad5/35 vectors by targeting the expression of the essential E1 and E4 genes; in addition, some vectors had the E1Delta24 deletion. We analyzed eleven promoters for their activity in glioblastoma cells and determined the specificity of eight replicative adenovirus vectors in vitro. We evaluated the most promising vectors with E1/E4 under the control of the GFAP/Ki67 or E2F-1/COX-2 promoters, and the native Ad5 or the chimeric Ad5/35 fiber for their antineoplastic activity in a subcutaneous and intracranial glioblastoma xenograft model. Animals treated with the Ad5/35-based vectors showed significantly smaller tumors and longer survival than those treated with the homologous Ad5 vectors; no significant toxicity was observed in the intracranial model. Our data suggest that Ad5/35-based vectors are promising tools for glioblastoma treatment.
Adjustable Gastric Banding and Conventional Therapy for Type 2 Diabetes (2008)

actr.org Identifier: ACTRN012605000159651.
Microwave antigen retrieval in immunocytochemistry: a study of 80 antibodies. (1994)

Microwave antigen retrieval represents an important technical advance within immunocytochemistry that will greatly increase the range of antibodies which can be used to study formalin fixed, paraffin wax embedded tissues.
Effect of Amino Multi Walled Carbon Nanotubes Reinforcement on the Flexural Properties of Neat Epoxy (2014)

The effect of amino multi-walled carbon nanotubes (MWCNTs) on the flexural properties of epoxy/ nanocomposites was studied. Sonication technique was employed for dispersion of amino MWCNTs in epoxy. The properties of both neat epoxy and nanocomposites extensively studied by using three point bend test and scanning electron microscopy. From the experimental results, it was found that reinforcement with carbon nanotubes improved the flexural properties, namely (a) flexural modulus, (b) flexural strength, (c) nonlinear deformation and (d) total flexural toughness.
Ultra-high Q planar silicon microdisk resonators for chip-scale silicon photonics (2007)

We report the fabrication and experimental characterization of an ultra-high Q microdisk resonator in a silicon-on-insulator (SOI) platform. We examine the role of the substrate in the performance of such microdisk resonators. While substrate leakage loss has warranted the necessity of substrate undercut structures in the past, we show here that the substrate has a very useful role to play for both passive chip-scale device integration as well as active electronic device integration. Two device architectures for the disk-on-substrate are studied in order to assess the possibility of such an integration of high Q resonators and active components. Using an optimized process for fabrication of such a resonator device, we experimentally demonstrate a Q approximately 3 x 10(6), corresponding to a propagation loss approximately 0.16 dB/cm. This, to our knowledge, is the maximum Q observed for silicon microdisk cavities of this size for disk-on-substrate structures. Critical coupling for a resonance mode with an unloaded Q approximately 0.7 x 10(6) is observed. We also report a detailed comparison of the obtained experimental resonance spectrum with the theoretical and simulation analysis. The issue of waveguide-cavity coupling is investigated in detail and the conditions necessary for the existence or lack of critical coupling is elaborated.
Nanomagnetic Particles for SQUID-Based Magnetically Labeled Immunoassay (2005)

With the increasing importance of SQUID-based magnetically labeled immunoassay, the study on the synthesis of controllable sizes of magnetic nanoparticles plays a role to promote the accuracy of the immunoassay. In this work, Fe/sub 3/O/sub 4/ nano-particles coated with a suitable bio-probe (biotin) are synthesized through chemical co-precipitation process to probe the bio-target (avidin). Through the synthesis developed here, the particle hydrodynamic diameter can be adjusted from 30 to 90 nm, which provide candidates for probing various bio-targets in the future. The amount of the magnetically labeled avidin is then analyzed via measuring the saturated magnetization or the remanence of the sample by using a SQUID magnetometer.
Recent improvements and benchmark results for the Paramax ATIS system (1992)

This paper describes three relatively domain-independent capabilities recently added to the Paramax spoken language understanding system: non-monotonic reasoning, implicit reference resolution, and database query paraphrase. In addition, we discuss the results of the February 1992 ATIS benchmark tests. We describe a variation on the standard evaluation metric which provides a more tightly controlled measure of progress. Finally, we briefly describe an experiment which we have done in extending the n-best speech/language integration architecture to improving OCR accuracy.
Human marrow erythropoiesis in culture. I. Characterization of methylcellulose colony assay (1976)

We examined the morphological and functional characteristics of human marrow erythrocytes cultured with a recently developed methylcellulose colony assay technique. Erythrocytic cells in various stages of development were observed, and a significant degree of maturational synchrony within individual colonies was noted. By light microscopy, colonies consisting of late normoblasts appeared compact, had an orange hue attributable to their hemoglobin, and demonstrated pseudoperoxidase activity, whereas colonies composed of early erythroblasts grew less compact or in clusters of smaller cell aggregates and showed no reddish tinge. Colonies possessing intermediate features were also observed. Maturational synchrony of individual colonies was confirmed using ransmission and scanning electron microscopy. The ultrastructure and cytochemistry of most immature cells were normal. The mature erythrocytes, however, were severely microcytic and hypochromic and contained one to several Heinz bodies. These defects in the cytoplasmic maturation of erythrocytes corresponded with impaired granulocytic maturation in culture, which we observed previously, and suggest environmental or nutritional defects in culture. Linearity of the method was confirmed using five normal bone marrows. Erythropoietin dose-responses observed in ten normal marrows were comparable to the previously reported results and revealed significant variation in individual plating efficiencies.
Endonasal Endoscopic Duraplasty: Our Experience (2006)

Our experience confirmed that endoscopic surgery is an effective and safe method of treatment for most CSF leaks. A variety of different endoscopic techniques allowed CSF leaks to be repaired in almost every site of the anterior skull base with very few exceptions.
Efficient remote block-level I/O over an RDMA-capable NIC (2006)

Modern storage systems are required to scale to large storage capacities and I/O throughput in a cost effective manner. For this reason, they are increasingly being built out of commodity components, mainly PCs equipped with large numbers of disks and interconnected of high-performance system area networks. A main issue in these efforts is to achieve high I/O throughput over commodity, low-cost system area networks and commodity operating systems.In this work, we examine in detail the performance of remote block-level storage I/O over commodity, RDMA-capable network interfaces and networks. We examine the support that is required from the network interface for achieving high throughput. We also examine in detail the overheads associated in kernel-level protocols for networked storage access. We find that base system performance is limited by (a) interrupt cost, (b) request size, and (c) protocol message size. We examine the impact of techniques to alleviate these factors and find that our techniques combined can improve throughput by up to 100% over a simpler unoptimized configuration. Our current prototype is able to achieve a throughput of about 200 MBytes/s over a network that is capable of delivering about 500 MBytes/s. We identify major limiting factors, mostly at the I/O target-side.
The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling (1997)

Convincing evidence has accumulated to identify the Frizzled proteins as receptors for the Wnt growth factors. In parallel, a number of secreted frizzled-like proteins with a conserved N-terminal frizzled motif have been identified. One of these proteins, Frzb-1, binds Wnt-1 and Xwnt-8 proteins and antagonizes Xwnt-8 signaling in Xenopus embryos. Here we report that Frzb-1 blocks Wnt-1 induced cytosolic accumulation of beta-catenin, a key component of the Wnt signaling pathway, in human embryonic kidney cells. Structure/function analysis reveals that complete removal of the frizzled domain of Frzb-1 abolishes the Wnt-1/Frzb-1 protein interaction and the inhibition of Wnt-1 mediated axis duplication in Xenopus embryos. In contrast, removal of the C-terminal portion of the molecule preserves both Frzb-Wnt binding and functional inhibition of Wnt signaling. Partial deletions of the Frzb-1 cysteine-rich domain maintain Wnt-1 interaction, but functional inhibition is lost. Taken together, these findings support the conclusion that the frizzled domain is necessary and sufficient for both activities. Interestingly, Frzb-1 does not block Wnt-5A signaling in a Xenopus functional assay, even though Wnt-5A coimmunoprecipitates with Frzb-1, suggesting that coimmunoprecipitation does not necessarily imply inhibition of Wnt function.
Vibrational Energy Flow and Chemical Reactions (2004)

How vibrational energy flows in molecules has recently become much better understood through the joint efforts of theory, experiment, and computation. The phenomenology of energy flow is much richer than earlier thought. We now know energy flow depends on the local structure of molecular vibrational state space. The details of the theoretically predicted transition from localized vibrations to free flow, where the molecule can act as its own heat bath, are now well-established experimentally. Energy flow is a quantum diffusive process leading to nonexponential decays, also seen in experiment. The slowness of energy flow in activated molecules causes substantial deviation from statistical Rice-Ramsperger-Kassel-Marcus (RRKM) theories for low barrier rate processes, such as isomerization. Quantitative calculations of rates in those cases are now possible.
A new dataset of computed-tomography angiography images for computer-aided detection of pulmonary embolism (2018)

The lack of publicly available datasets of computed-tomography angiography (CTA) images for pulmonary embolism (PE) is a problem felt by physicians and researchers. Although a number of computer-aided detection (CAD) systems have been developed for PE diagnosis, their performance is often evaluated using private datasets. In this paper, we introduce a new public dataset called FUMPE (standing for Ferdowsi University of Mashhad's PE dataset) which consists of three-dimensional PE-CTA images of 35 different subjects with 8792 slices in total. For each benchmark image, two expert radiologists provided the ground-truth with the assistance of a semi-automated image processing software tool. FUMPE is a challenging benchmark for CAD methods because of the large number (i.e., 3438) of PE regions and, more especially, because of the location of most of them (i.e., 67%) in lung peripheral arteries. Moreover, due to the reporting of the Qanadli score for each PE-CTA image, FUMPE is the first public dataset which can be used for the analysis of mortality and morbidity risks associated with PE. We also report some complementary prognosis information for each subject.
Module placement with boundary constraints using B*-trees (2002)

The module placement problem is to determine the co-ordinates of logic modules in a chip such that no two modules overlap and some cost (e.g. silicon area, interconnection length, etc.) is optimised. To shorten connections between inputs and outputs and/or make related modules adjacent, it is desired to place some modules along the specific boundaries of a chip. To deal with such boundary constraints, we explore the feasibility conditions of a B*-tree with boundary constraints and develop a simulated annealing-based algorithm using B*-trees. Unlike most previous work, the proposed algorithm guarantees a feasible B*-tree with boundary constraints for each perturbation. Experimental results show that the algorithm can obtain a smaller silicon area than the most recent work based on sequence pairs.
Oxide-supported Ir nanodendrites with high activity and durability for the oxygen evolution reaction in acid PEM water electrolyzers (2015)

Reducing the noble-metal catalyst content of acid Polymer Electrolyte Membrane (PEM) water electrolyzers without compromising catalytic activity and stability is a goal of fundamental scientific interest and substantial technical importance for cost-effective hydrogen-based energy storage. This study presents nanostructured iridium nanodendrites (Ir-ND) supported on antimony doped tin oxide (ATO) as efficient and stable water splitting catalysts for PEM electrolyzers. The active Ir-ND structures exhibited superior structural and morphological properties, such as particle size and surface area compared to commercial state-of-art Ir catalysts. Supported on tailored corrosion-stable conductive oxides, the Ir-ND catalysts exhibited a more than 2-fold larger kinetic water splitting activity compared with supported Ir nanoparticles, and a more than 8-fold larger catalytic activity than commercial Ir blacks. In single-cell PEM electrolyzer tests, the Ir-ND/ATO outperformed commercial Ir catalysts more than 2-fold at technological current densities of 1.5 A cm<sup>-2</sup> at a mere 1.80 V cell voltage, while showing excellent durability under constant current conditions. We conclude that Ir-ND/ATO catalysts have the potential to substantially reduce the required noble metal loading, while maintaining their catalytic performance, both in idealized three-electrode set ups and in the real electrolyzer device environments.
Development of Centrifugal Downhole Oil/Water Separator: Simulation and Experimental Study (2016)

Abstract In the shadow of low oil prices, it is necessary to develop economically and environmentally friendly solutions. In oil and gas industry, majority of the production stream is water. This water is produced with the hydrocarbon to surface. This requires the separation of the fluids produced and then treating those streams to abide with environmental regulations and clients' specifications. CDOWS (Centrifugal Downhole Oil Water Separator) technology is believed to provide high separation quality, high oil recovery with reduction of operating costs and less surface facilities. The development process involves simulation of tubular centrifuge using a computational fluid dynamics (CFD) software to analyze the parameters affecting separation. After that, an experimental set up is erected which mimics in-well CDOWS. The novel design of the tool involves specially designed weir to collect the oil and water through concentric tube configuration. The parameters tested through simulation include; flow rate, RPM, tubing length, tubing diameter, API and oil/water ratios. The experimental set-up is used to confirm the sepration in the rotating tube as it is made of acrylic material. The CFD model involves a rotating cylinder (tubing) in which oil and water are introduced from the inlet. The feed of oil and water exhibits high centrifugal forces resulting in their separation through and to the outlet of the tubing. The experimental design mimics the actual in-well design which can be implemented in a well. The design can be configured easily to change the tubing parameters. After conducting the studies, a sensitivity analysis using design of experiment approach (DOE) and response surface plots is produced to emphasize on parameters and their interaction effects. Findings include better separation using higher RPM, ID, L, water salinity, API. The most influential factor is RPM which can be controlled and thus will define costs for later stages of the project. This paper presents the first work on CDOWS which is analogous to in-well configuration aiming for a solution with reduced costs.
Production of a new compound, 7,10-dihydroxy-8-(E)-octadecenoic acid from oleic acid byPseudomonas sp. PR3 (1991)

Sixty-two cultures from the ARS Culture Collection and 10 cultures isolated from soil and water samples collected in Illinois were screened for their ability to convert agricultural oils to value-added industrial chemicals. A new compound, 7,10-dihydroxy-8-(E)-octadecenoic acid (DOD) was produced from oleic acid by a new strain,Pseudomonas sp. PR3 isolated from a water sample in Morton, IL. Strain PR3 is a motile, small rod-shaped, Gram-negative bacterium. It has multiple polar flagellae and is oxidase-positive. Strain PR3 grows aerobically and cannot grow anaerobically. The strain produces white, smooth colonies on agar plate and no water-soluble pigment. The yield of the product was greater than 60%. The optimum time, pH and temperature for the production of DOD were: 2 days, 7.0, and 30°C, respectively. Glycerol and dextrose support the growth of strain PR3, but the cells grown from the former failed to catalyse the conversion of oleic acid to DOD. The production of DOD is unique in that it involves a hydroxylation at two positions and a rearrangement of the double bond of the substrate molecule.