gebhart/patrepeval huggingface dataset:
The Special Educational Needs and Disability Act 2001--The implications for higher education (2003)

(2003). The Special Educational Needs and Disability Act 2001--The implications for higher education. Education and the Law: Vol. 15, No. 1, pp. 19-45.
Improved Opportunistic Beamforming in Ricean Channels (2006)

In order to improve the performance of opportunistic beamforming in Ricean channels, we propose an improved opportunistic beamforming scheme which forms beams intelligently to the users. First, a new concept of the generalized Ricean distribution is introduced. On the basis of this theory, we propose a maximum-likelihood (ML) estimator of the directions of arrival of the users, and we derive the Cramer-Rao lower bound to evaluate the performance of the ML estimator. Furthermore, the generalized Ricean K-factors are estimated by a moment-based method. With the same pilot overhead in the downlink and with the same feedback overhead in the uplink, the improved scheme considerably outperforms conventional opportunistic beamforming
Survival of the Ideas that Fit: An Evolutionary Analogy for the Use of Evidence in Policy (2007)

This paper explores bias in the use of evidence in policy. It argues that existing models of the evidence–policy relationship neglect the tendency for attention to be paid only to that evidence helpful to the interests of powerful social groups. An evolutionary analogy is used to explain how this bias arises, without the need for irrationality or conspiracy on the part of policy makers. Examples are given in the fields of drug, asylum and other policies, and the possible responses by researchers to the biased use of research evidence are discussed.
Toward biological antifouling surface coatings: Marine bacteria immobilized in hydrogel inhibit barnacle larvae (1995)

A new concept for the prevention of macrofouling has been developed, based on the immobilization of marine bacteria in hydrogels. A marine Gram‐negative bacterium used in this study produces at least two extracellular components that inhibit the settlement of invertebrate larvae on surfaces. It was demonstrated that a 3–5% monomer concentration allowed for an optimum polyaclrylamide gel coating both with respect to the viability of bacteria and barnacle larvae as well as to appropriate mechanical properties and gel pore size. In laboratory experiments these gel surfaces proved to be less favorable for the viability of barnacle larvae than gel surfaces without immobilized bacteria.
Characterization of the Adhesin of <i>Escherichia coli</i> F18 Fimbriae (2001)

Previous research has suggested that the adhesin encoded by the F18 fimbrial operon in Escherichia coli is either the FedE or FedF protein. In this work, we show that anti-FedF antibodies, unlike anti-FedE serum, were able to inhibit E. coli adhesion to porcine enterocytes. Moreover, specific adhesion to enterocytes was shown with purified FedF-maltose binding protein.
PET/CT in cardiology (2006)

With the event of multimodality imaging, the combination of structural and functional information provided by new PET/CT technology will increase the diagnostic range in cardiovascular disease. State of the art multislice CT imaging allows not only the delineation of regional coronary calcification but also non-invasive coronary angiography. Coronary calcification has been shown to be of independent prognostic value. Together with the functional evaluation of rest and stress myocardial perfusion both parameters, calcification and angiography, can be used to risk stratify individual patients with suspected or proven coronary artery disease. Perfusion abnormalities can be correlated to regional coronary anatomy and guidance of therapeutic intervention will be provided. In addition, the data acquisition allows delineation of regional and global wall motion as well as assessment of left ventricular volumes in patients with advanced coronary artery disease and symptoms of heart failure. Using metabolic imaging the extent of viable myocardium can be related to regional wall motion abnormalities and prognostic information regarding revascularization and clinical outcome obtained. With the advent of molecular imaging the co-registration of coronary anatomy as well as scintigraphic signals e. g. inflammation may be helpful to identify patients with unstable plaques or accelerated atherosclerosis.
The Endoplasmic Reticulum of Mung Bean Cotyledons (1980)

The subcellular localization of two hydrolases (ribonuclease and vicilin peptidohydrolase) which are synthesized de novo in the cotyledons of mung bean seedlings was studied. Earlier experiments had shown that both enzymes accumulate in the protein bodies in the course of seedling growth. Two methods to fractionate subcellular organelles were used to demonstrate that a significant proportion of the enzymes is organelle-associated. This proportion is highest (up to 50% for vicilin peptidohydrolase and 15% for ribonuclease) when synthesis of the enzymes has just started. Evidence obtained with isopycnic sucrose gradients indicates that both hydrolases are associated with membranes rich in NADH-cytochrome c reductase, a marker enzyme for the endoplasmic reticulum (ER). The hydrolases band with the NADH-cytochrome c reductase under conditions where the ribosomes remain attached or are detached from the ER-derived vesicles. Treatment of the ER-derived vesicles with Triton X-100 shows that vicilin peptidohydrolase and vesicle membranes can be physically separated without dissolving the membranes, indicating that the proteinase is soluble within the vesicles. These data support the conclusion that the ER is involved in the transport of ribonuclease and proteinase to the protein bodies.
Isolation of a Chinese hamster fibroblast variant defective in dihydroxyacetonephosphate acyltransferase activity and plasmalogen biosynthesis: use of a novel two-step selection protocol (1998)

We have developed a two-step selection protocol to generate a population of Chinese hamster ovary (CHO) cell variants that are plasmalogen-deficient, but contain intact, functional peroxisomes (plasmalogen-/peroxisome+). This involved sequential exposures of a mutagenized cell population to photodynamic damage by using two different pyrene-labelled sensors, 9-(1'-pyrene)nonanol and 12-(1'-pyrene)dodecanoic acid. By this procedure we generated several isolates, all except one of which displayed a severe decrease in plasmalogen biosynthesis. Further characterization of one of the plasmalogen-deficient isolates, NRel-4, showed that it contained intact, functional peroxisomes. Whole-cell homogenates from NRel-4 displayed severely decreased dihydroxyacetone phosphate acyltransferase, which catalyses the first step in plasmalogen biosynthesis. NRel-4 and another, recently described, plasmalogen-deficient cell line, NZel-1 [Nagan, Hajra, Das, Moser, Moser, Lazarow, Purdue and Zoeller (1997) Proc. Natl. Acad. Sci. U.S. A. 94, 4475-4480] were hypersensitive to singlet oxygen, supporting the notion of plasmalogens as radical oxygen scavengers. Wild-type-like resistance could be conferred on NRel-4 upon restoration of plasmalogen content by supplementation with a bypass compound, sn-1-hexadecylglycerol. NRel-4 and other plasmalogen-/peroxisome+ strains will allow us to examine further the role of ether lipids in cellular functions without complications associated with peroxisome deficiency, and might serve as an animal cell model for certain forms of the human genetic disorder rhizomelic chondrodysplasia punctata.
Metabolic regulation, activity state, and intracellular binding of glucokinase in insulin-secreting cells. (1999)

Regulation of glucose-induced insulin secretion is crucially dependent on glucokinase function in pancreatic beta-cells. Glucokinase mRNA expression was metabolically regulated allowing continuous translation into enzyme protein. Glucokinase enzyme activity in the beta-cell was exclusively regulated by glucose. Using a selective permeabilization technique, different intracellular activity states of the glucokinase enzyme in bioengineered glucokinase-overexpressing RINm5F tissue culture cells were observed. These results could be confirmed in analogous experiments with dispersed islet cells. A diffusible glucokinase fraction with high enzyme activity could be distinguished from an intracellularly bound fraction with low activity. Glucose induced a significant long-term increase of the active glucokinase fraction. This effect was accomplished through the release of glucokinase enzyme protein from an intracellular binding site of protein character. The inhibitory function of this protein factor was abolished through proteolytic digestion or heat inactivation. Northern blot analyses revealed that this binding protein was not identical to the well-known liver glucokinase regulatory protein. This hitherto unknown new protein factor may have the function of a glucokinase regulatory protein in the pancreatic beta-cell, which may regulate glucokinase enzyme activity in a glucose-dependent manner.
A new type SPUDT SAW for use in high frequency around 2 GHz (2003)

This paper introduces a new type of SPUDT structure, which enables the design of SAW filters or delay-lines up into the 2 GHz range. The structure consists of two groups of spatially harmonic transducers e.g. Se=5 (+ + - + -) or Se=8 (+ + - + - - + -) and one group of reflectors positioned between the two groups of harmonic transducers. In the paper, the general operating principle of the new SPUDT is discussed. To confirm this new technique, a slanted type SAW filter using the new SPUDT structure with central frequency of 2.14 GHz was designed and fabricated. The directionality of this new SPUDT structure has been demonstrated by measurement.
Das Dispiro[5.1.5.1]tetradecan-Gerüst als Baustein für thermotrope Flüssigkristalle / Thermotropic Liquid Crystals Containing the Dispiro[5.1.5.1]tetradecane Unit (1986)

Abstract Several 3 .11-disubstituted dispiro[5.1.5.1]tetradecane-7,14-dions were prepared and the cis/trans-isomers were separated. The trans -stereoisomers were converted into the gem-dihalide ketones and mono- and dithioketones. The phase transfer temperatures were determined. Liquid crystal phases were observed.
Anti-scatter grid artifact elimination for high resolution x-ray imaging CMOS detectors (2015)

Higher resolution in dynamic radiological imaging such as angiography is increasingly being demanded by clinicians; however, when standard anti-scatter grids are used with such new high resolution detectors, grid-line artifacts become more apparent resulting in increased structured noise that may overcome the contrast signal improvement benefits of the scatter-reducing grid. Although grid-lines may in theory be eliminated by dividing the image of a patient taken with the grid by a flat-field image taken with the grid obtained prior to the clinical image, unless the remaining additive scatter contribution is subtracted in real-time from the dynamic clinical image sequence before the division by the reference image, severe grid-line artifacts may remain. To investigate grid-line elimination, a stationary Smit Röntgen X-ray grid (line density: 70 lines/cm, grid ratio 13:1) was used with both a 75 micron-pixel CMOS detector and a standard 194 micron-pixel flat panel detector (FPD) to image an artery block insert placed in a modified uniform frontal head phantom for a 20 × 20cm FOV (approximately). Contrast and contrast-to-noise ratio (CNR) were measured with and without scatter subtraction prior to grid-line correction. The fixed pattern noise caused by the grid was substantially higher for the CMOS detector compared to the FPD and caused a severe reduction of CNR. However, when the scatter subtraction corrective method was used, the removal of the fixed pattern noise (grid artifacts) became evident resulting in images with improved CNR.
Identification of CD4-Binding Site Dependent Plasma Neutralizing Antibodies in an HIV-1 Infected Indian Individual (2015)

Dissecting antibody specificities in the plasma of HIV-1 infected individuals that develop broadly neutralizing antibodies (bNAbs) is likely to provide useful information for refining target epitopes for vaccine design. Several studies have reported CD4-binding site (CD4bs) antibodies as neutralization determinants in the plasma of subtype B-infected individuals; however there is little information on the prevalence of CD4bs specificities in HIV-infected individuals in India. Here, we report on the presence of CD4bs antibodies and their contribution to virus neutralization in the plasma from a cohort of HIV-1 infected Indian individuals. Plasma from 11 of the 140 HIV-1 infected individuals (7.9%) studied here exhibited cross-neutralization activity against a panel of subtype B and C viruses. Analyses of these 11 plasma samples for the presence of CD4bs antibodies using two CD4bs-selective probes (antigenically resurfaced HXB2gp120 core protein RSC3 and hyperglycosylated JRFLgp120 mutant ΔN2mCHO) revealed that five (AIIMS 617, 619, 627, 642, 660) contained RSC3-reactive plasma antibodies and only one (AIIMS 660) contained ΔN2mCHO-reactive antibodies. Plasma antibody depletion and competition experiments confirmed that the neutralizing activity in the AIIMS 660 plasma was dependent on CD4bs antibodies. To the best of our knowledge, this is the first study to report specifically on the presence of CD4bs antibodies in the plasma of a cohort of HIV-1 infected Indian donors. The identification of CD4bs dependent neutralizing antibodies in an HIV-1 infected Indian donor is a salient finding of this study and is supportive of ongoing efforts to induce similar antibodies by immunization.
Temporal Dierences-Based Policy Iteration and Applications in Neuro-Dynamic Programming 1 (1997)

We introduce a new policy iteration method for dynamic programming problems with discounted and undiscounted cost. The method is based on the notion of temporal dierences, and is primarily geared to the case of large and complex problems where the use of approximations is essential. We develop the theory of the method without approximation, we describe how to embed it within a neuro-dynamic programming/reinforcement learning context where feature-based approximation architectures are used, we relate it to TD( ) methods, and we illustrate its use in the training of a tetris playing program.
Synthesis and Characterization of Mononuclear Amidogold(<scp>III</scp>) Complexes − Crystal Structure of [Au(N<sub>2</sub>C<sub>10</sub>H<sub>7</sub>(CMe<sub>2</sub>C<sub>6</sub>H<sub>4</sub>)‐6](NHC<sub>6</sub>H<sub>3</sub>Me<sub>2</sub>‐2,6)][PF<sub>6</sub>] − Oxidation of 4‐Methylaniline to Azotoluene (2003)

Abstract Mononuclear amidogold( III ) complexes [Au(C,N,N)(NRR′)][PF 6 ] [C,N,N = N 2 C 10 H 7 (CMe 2 C 6 H 4 )‐6, where N 2 C 10 H 8 = 2,2′‐bipy; R = H, R′ = p ‐tolyl ( 5 ), o ‐xylyl ( 6 ), isobutyl ( 7 ), sec ‐butyl ( 8 ), R = R′ = Et ( 9 )], [Au(C,N)(AcO)(NHC 6 H 4 NO 2 ‐4)] ( 10 ) [C,N = NC 5 H 4 (CH 2 C 6 H 4 )‐2, where NC 5 H 5 = py] and [Au(N,N)(NHC 6 H 4 NO 2 ‐4) 2 ][PF 6 ] ( 11 ) (N,N = 2,2′‐bipy), have been synthesized in fairly good yields by reaction of the hydroxo, methoxo, or acetato complexes 1 − 4 {[Au(C,N,N)(OR)][PF 6 ] [R = H ( 1 ), Me ( 2 )], [Au(C,N)(AcO) 2 ] ( 3 ), [Au(N,N)(OH) 2 ][PF 6 ] ( 4 )} with amines. The structure of [Au(C,N,N)(NHC 6 H 3 Me 2 ‐2,6)][PF 6 ] ( 6 ) has been determined by X‐ray diffraction. Reaction of the hydroxo complex 4 with NH 2 C 6 H 4 Me‐4 gives metallic gold, the protonated ligand [N,NH][PF 6 ] and organic products, the main one being azotoluene. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Tumour necrosis factor-alpha (TNF-α) in the host resistance to mycobacteria of distinct virulence (1995)

The relative virulence of different isolates of Mycobacterium avium has been linked to their capacity to trigger the secretion of TNF from the macrophages they infect. Smooth opaque (SmOp) variants of Myco. avium have been shown to trigger higher expression of TNF-alpha by macrophages in vitro than the smooth transparent (SmTr) variants. To analyse the role of TNF in resistance to infection by Myco. avium, we studied the infection by two different morphotypes of strain 2.151 of Myco. avium both in vitro and in vivo in the presence or absence of neutralizing antibodies to TNF. No effects were found in vitro regarding the growth of either isolate of Myco. avium. In vivo, only the virulent SmTr morphotype showed enhanced growth in the presence of the neutralizing antibodies. This enhancement occurred relatively late when priming for TNF secretion in vivo was evident. Among four isolates of Myco. avium, three virulent ones induced a marked priming for TNF release and one avirulent strain did not. Mycobacterium tuberculosis H37Ra, which is very active in inducing TNF release due to its lipoarabinomannan moiety, was used to compare with the previous results. The growth of H37Ra in macrophages was increased in vitro by the neutralization of TNF and neutralization of either TNF and/or interferon-gamma (IFN-gamma) enhanced the in vivo proliferation of this microbe in the spleen and liver of infected animals, whereas only the combination of both anti-TNF and anti-IFN-gamma enhanced bacterial proliferation in the lung. We conclude that resistance to the avirulent strains of Myco. avium did not involve TNF, but rather antimicrobial mechanisms expressed constitutively in the mononuclear phagocytes. In contrast, TNF plays an important role in the control of Myco. tuberculosis H37Ra infection.
Introduction to Advanced Integrated Wastewater Ponding Systems (1991)

Research Article| September 01 1991 Introduction to Advanced Integrated Wastewater Ponding Systems William J. Oswald William J. Oswald Search for other works by this author on: This Site PubMed Google Scholar Water Sci Technol (1991) 24 (5): 1–7. https://doi.org/10.2166/wst.1991.0106 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Share Icon Share Twitter LinkedIn Tools Icon Tools Cite Icon Cite Permissions Search Site Search nav search search input Search input auto suggest search filter All ContentAll JournalsThis Journal Search Advanced Search Citation William J. Oswald; Introduction to Advanced Integrated Wastewater Ponding Systems. Water Sci Technol 1 September 1991; 24 (5): 1–7. doi: https://doi.org/10.2166/wst.1991.0106 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex This content is only available as a PDF. © IWA Publishing 1991 Article PDF first page preview Close Modal You do not currently have access to this content.
Closed loop analog active gate driver for fast switching and active damping of SiC MOSFET (2018)

SiC MOSFETs have the capability to handle large di/dt and dv/dt. This can be used to reduce the switching losses, and thereby increase efficiency of the converter. But, even moderate amount of layout parasitic inductance and capacitance can cause significant detrimental effects on reliability and EMI of the power device. Present paper proposes a di/dt feed back based, current controlled active gate driver mechanism. It allows the device to operate at desired di/dt as well as dv/dt level, even under moderate layout parasitic. Proposed gate driver also tries to exploit certain benefits offered by the layout parasitic to further reduce the switching losses. Active damping and over shoot arresting features of the proposed gate driver can ensure fast switching speeds without compromising on the reliability and EMI of the device.
Determinants of coronary vascular calcification in patients with chronic kidney disease and end-stage renal disease: A systematic review (2004)

VC is a common observation in CKD and ESRD and is mainly related to age, length of time on dialysis therapy, and possibly dyslipidemia. The calcium-phosphorus balance and its related treatments are likely not related to this unique form of vascular calcification. Further research into the determinants and potential treatments for vascular calcification is warranted.
Predicting Android Application Security and Privacy Risk with Static Code Metrics (2017)

Android applications pose security and privacy risks for end-users. These risks are often quantified by performing dynamic analysis and permission analysis of the Android applications after release. Prediction of security and privacy risks associated with Android applications at early stages of application development, e.g. when the developer (s) are writing the code of the application, might help Android application developers in releasing applications to end-users that have less security and privacy risk. The goal of this paper is to aid Android application developers in assessing the security and privacy risk associated with Android applications by using static code metrics as predictors. In our paper, we consider security and privacy risk of Android application as how susceptible the application is to leaking private information of end-users and to releasing vulnerabilities. We investigate how effectively static code metrics that are extracted from the source code of Android applications, can be used to predict security and privacy risk of Android applications. We collected 21 static code metrics of 1,407 Android applications, and use the collected static code metrics to predict security and privacy risk of the applications. As the oracle of security and privacy risk, we used Androrisk, a tool that quantifies the amount of security and privacy risk of an Android application using analysis of Android permissions and dynamic analysis. To accomplish our goal, we used statistical learners such as, radial-based support vector machine (r-SVM). For r-SVM, we observe a precision of 0.83. Findings from our paper suggest that with proper selection of static code metrics, r-SVM can be used effectively to predict security and privacy risk of Android applications.
Terrorism and Homeland Security (2010)

Gemini: Terrorism and Homeland Security Dale L. June Terrorism in the Twenty-First Century: How Are Governments Coping? Michael Savasta A Manifesto of War and Hate: A Look Inside an al-Qaeda Manual Dale L. June The Concept of Martyrdom Dr. A. K. Mohammed Zentropism and Homeland Security Jonathan Ross The Elephant in the Room: Homeland Security and the Unresolved Challenge of Insider Threats Howard Clarke Thinking Locally, Acting Globally: Resurgent Islamism, Transnational Objectives, and Regional Instability Keely Fahoum Suicide Bombing as an Ultimate Terrorist Tool Dr. A. K. Mohammed The Battle of Ideas: Political Warfare versus Psychological Operations Dr. Monte R. Bullard United States and European Union Antiterrorism Cooperative Efforts David G. Popp Trends in Strategic Security: The New Warfare Dale L. June Deprivation, Occupation, and Social Change: Hamas and Lebanese Hezbollah's Evolution from Bombs to Ballot Boxes Keely Fahoum The Diminution of the Citizen in the Age of Homeland Security Debra D. Burrington Chemical, Biological, Radiological, and Nuclear Terrorism: Weapons of Mass Terror Richard J. Niemann Apocalypse: Courage and Commitment Dale L. June Homeland Security: What Everyone Can Do. Deter! Detect! Disrupt! Bart Bechtel The HUMINT Side of Competitive Intelligence Wayne Taylor Terrorist Threats South of the Border Dr. Juan A. Bacigalupi Mexico Violence That Threatens Our Southern Border: Ripening Conditions for Escalated Terrorism Domestically and Internationally Immediately South of the United States Augusto D'Avila Common Chemicals as Precursors in Constructing Improvised Explosive Devices: Tools for Locating Bomb Makers and Their Clandestine Labs Richard J. Niemann Panopti(con): Art and the Aesthetics of Dissent Claudia M. Huiza Policing the Future: Homeland Security and Terrorism: Nineteen Eighty-Four and the Terminator Dale L. June Index