gebhart/patrepeval huggingface dataset:
Effects of Plasmalogen on Patients with Mild Cognitive Impairment: A Randomized, Placebo-Controlled Trial in Japan (2018)

Objective: It has been shown that plasmalogens (Pls) in the brain tissue and blood decrease among Alzheimer’s disease (AD) patients. We first confirmed the effects of Pls on animal AD models, and subsequently reported that the ingestion of 1 mg Pls was effective for AD patients in a randomized, placebo-controlled trial with mild cognitive impairment (MCI) or mild AD patients. The present study examined the efficacy of orally administered Pls on patients with MCI enrolled in the previous trial in terms of individual domains of the Mini Mental State Examination-Japanese (MMSE-J). Methods: The present analysis used 178 patients with MCI out of the 276 patients with either MCI or AD in the previously reported trial, and assessed the 24 week change in the domain-specific scores of the MMSE-J. Originally, the randomized, placebo-controlled trial was performed for 276 patients at age of 60-85 years who had the MMSE-J score of 20-27 points and the Geriatric Depression Scale-Short Version-Japanese Version (GDS-S-J) score of 5 points or less. The patients were randomly allocated to either a treatment with 1 mg of scallop-derived Pls daily or a placebo treatment. The primary outcome was a 24 week change in the MMSE-J. The registered number of the trial is UMIN000014945. Results: The MMSE-J total score improved statistically significantly in the Pls treatment but not in the placebo treatment, resulting in no significant between-treatment difference. With respect to one of the MMSE-J domains, orientation to place, the Pls treatment showed a significant improvement and the placebo treatment showed no such improvement; the between-treatment difference was statistically significant (p=0.003). The domain for orientation to time worsened significantly at endpoint in the placebo treatment, while the Pls treatment showed no worsening. However, the between-treatment difference failed to reach the statistical significance. No significant change was found in either treatment regarding the other MMSE-J domains. Conclusion: These findings suggest that oral administration of 1 mg Pls enhances cognitive function of MCI patients, especially orientation to place.
A structured network architecture for adaptive language acquisition (1992)

The authors report on the progress in understanding how to build devices which adaptively acquire the language for their task. The generic device is an information-theoretic connectionist network embedded in a feedback control system. They investigate the capability of the network to learn associations between messages and meaningful responses to them as a task increases in size and complexity. Specifically, the authors consider how one might reflect task structure in the network architecture in order to provide improved generalization capability in language acquisition. They propose a product network, which provides improved generalization by factoring the associations between words and action through semantic primitives. The product network is being evaluated in several experimental systems, including a 1000-action Almanac data retrieval system. They describe these systems and provide details on two preliminary experiments.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Simultaneous Multiwell VSP using Distributed Acoustic Sensing (2013)

In a collaborative project between Silixa, Weatherford and Statoil, simultaneous multiwell VSP data were successfully acquired using intelligent Distributed Acoustic Sensing (iDAS). The iDAS enables the use of an optic fibre as a massive seismic sensor array. In this field trial the iDAS was retrofitted to existing fibres installed for other purposes. Simultaneous measurements were carried out using 4 iDAS units retrofitted to fibres in three different wells coming up to the same platform. Several seismic lines were shot, e.g. one above each of the well tracks, while listening in the well directly below the shots and also in neighbouring wells at an angle to the shot line. All three wells were producing during the trial and the downhole seismic data were acquired without disturbing the well operations. Consequently data hold information about the flow in the well in addition to the seismic information.
Identification of a Novel C-Terminal Cleavage of Crimean-Congo Hemorrhagic Fever Virus PreG <sub>N</sub> That Leads to Generation of an NS <sub>M</sub> Protein (2007)

The structural glycoproteins of Crimean-Congo hemorrhagic fever virus (CCHFV; genus Nairovirus, family Bunyaviridae) are derived through endoproteolytic cleavage of a 1,684-amino-acid M RNA segment-encoded polyprotein. This polyprotein is cotranslationally cleaved into the PreGN and PreGC precursors, which are then cleaved by SKI-1 and a SKI-1-like protease to generate the N termini of GN and GC, respectively. However, the resulting polypeptide defined by the N termini of GN and GC is predicted to be larger (58 kDa) than mature GN (37 kDa). By analogy to the topologically similar M segment-encoded polyproteins of viruses in the Orthobunyavirus genus, the C-terminal region of PreGN that contains four predicted transmembrane domains may also contain a nonstructural protein, NSM. To characterize potential PreGN C-terminal cleavage events, a panel of epitope-tagged PreGN truncation and internal deletion mutants was developed. These constructs allowed for the identification of a C-terminal endoproteolytic cleavage within, or very proximal to, the second predicted transmembrane domain following the GN ectodomain and the subsequent generation of a C-terminal fragment. Pulse-chase experiments showed that PreGN C-terminal cleavage occurred shortly after synthesis of the precursor and prior to generation of the GN glycoprotein. The resulting fragment trafficked to the Golgi compartment, the site of virus assembly. Development of an antiserum specific to the second cytoplasmic loop of PreGN allowed detection of cell-associated NSM proteins derived from transient expression of the complete CCHFV M segment and also in the context of virus infection.
Autoantibodies in paraneoplastic syndromes associated with small‐cell lung cancer (1988)

An antineuronal autoantibody has been identified in serum from 14 patients, 8 women and 6 men, with small-cell lung carcinoma (SCLC) and a neurologic disorder. Neurologic symptoms began prior to diagnosis of the SCLC in 12 patients. The dominant neurologic disorder was a subacute sensory neuronopathy (SSN) in eight patients, SSN plus lower motor neuron weakness (2 patients), SSN plus autonomic neuropathy (1 patient), cerebellar ataxia (1 patient), myelopathy (1 patient), and multifocal nervous system disease (encephalomyelitis) in one patient. The presence of the same autoantibody in patients with SSN, encephalomyelitis, and autonomic neuropathy suggests that these diseases are different manifestations of the same nosologic process. With one exception, treatment of the tumor, immunosuppressive drugs, and plasmapheresis did not influence the course of the neurologic illness. The autoantibody was not identified in sera from more than 400 controls subjects, including patients with SSN associated with other tumors, SSN without malignancy, other paraneoplastic syndromes, and SCLC without neurologic symptoms. The autoantibody is a highly specific marker of the paraneoplastic syndromes associated with SCLC and its detection in a patient not known to have cancer should prompt a careful search for SCLC.
Flexible and Adhesive Surface Enhance Raman Scattering Active Tape for Rapid Detection of Pesticide Residues in Fruits and Vegetables (2016)

The efficient extraction of targets from complex surfaces is vital for technological applications ranging from environmental pollutant monitoring to analysis of explosive traces and pesticide residues. In our present study, we proposed a proof-of-concept surface enhance Raman scattering (SERS) active substrate serving directly to the rapid extraction and detection of target molecules. The novel substrate was constructed by decorating the commercial tape with colloidal gold nanoparticles (Au NPs), which simultaneously provides SERS activity and "sticky" of adhesive. The utility of SERS tape was demonstrated by directly extracting pesticide residues in fruits and vegetables via a simple and viable "paste and peel off" approach. The obtained strong and easily distinguishable SERS signals allow us to detect various pesticide residues such as parathion-methyl, thiram, and chlorpyrifos in the real samples with complex surfaces including green vegetable, cucumber, orange, and apple.
Secretory IgA antibodies synergize with IgG in promoting ADCC by human polymorphonuclear cells, monocytes, and lymphocytes (1981)

Secretory IgA antibody which alone did not mediate antibody-dependent cytotoxicity (ADCC) by polymorphonuclear leukocytes (PMNs), monocytes, or lymphocytes, caused significant elevation of the IgG-ADCC carried out by these cells. This corresponds to the expression of receptors for both IgA and IgG on subpopulations of PMNs and monocytes, and implies that some lymphocytes may bear both receptors. It also suggests a mechanism whereby secretory IgA participates in immune defense.
Scene geometry from moving objects (2014)

It has been observed that in most videos recorded by surveillance cameras the image size of an object is a linear function of the y coordinate of its image location. This simple linear relationship holds in the most common surveillance camera configurations, where objects move on a planar surface and the camera's X axis is parallel to that plane. This linear relationship enables us to easily perform and enhance several geometric tasks based on tracking an object over a few frames: (i) computing the horizon; (ii) computing the relative real world sizes of objects in the scene based on their image appearance; (iii) improving tracking by constraining an object's location and size. When the the camera's X axis is not parallel to the ground plane, after tracking a couple of objects it is possible to find the rotation which rectifies the video so that its new X axis is parallel to the ground plane.
Novel Resonant Transition PWM inverters: Synthesis and analysis (2006)

This paper presents a generalized concept concerning the Resonant Transition technique. It is based on the Resonant Transition mechanism requirements, i.e, on the auxiliary circuit functionality. The proposed Resonant Transition Concept permits to newcomers to perceive the Resonant Transition techniques as a whole instead of dissimilar soft-switching techniques. Furthermore, by means of this concept a unique methodology to analyze and synthesize the Resonant Transition converters is developed. The easy assessment of the Resonant Transition needs makes possible the development of novel Resonant Transition topologies with improved characteristics. The paper focuses on Zero-Current Transition (ZCT) and Zero-Current-Zero-Voltage Transition (ZCZVT) Inverters, which are suitable for medium and high power applications where minority carrier devices are predominant. Theoretical analysis is verified by means of experimental results obtained from laboratory prototypes rated at 1kW, 40kHz.
Introduction (1988)

Long gone are the days when the achievement of a basic nursing qualification was an end in itself. Now it is simply the first step on a career path which can lead upwards or sideways in many different directions.
Induction of collagen mineralization by a bone sialoprotein-decorin chimeric protein (2001)

The observation that hydroxyapatite (HA) formation from metastable solutions can be induced by nucleating proteins such as bone sialoprotein (BSP) suggests a possible treatment for bone defects. The introduction of a mixture of nucleating protein and type I collagen should result in a defect becoming filled with a mineralized collagenous matrix that is biologically and mechanically compatible and capable of being remodeled. To create a nucleating protein that would interact with collagen fibrils, we combined the putative collagen-binding site of mouse decorin with one of two putative HA-nucleating sites of pig BSP. The resulting chimeric protein induced the formation of HA crystals in a steady-state agarose gel system and bound with high affinity to fibrillar type I collagen. The addition of chimeric protein to collagen gels perfused with low concentrations of calcium and phosphate resulted in the deposition of large, apparently needle-shaped HA crystals on the surface of collagen fibrils. These findings suggest that the BSP-decorin chimeric protein could be capable of inducing the mineralization of collagen in vivo.
A new search method for ranking short text messages using semantic features and cluster coherence (2010)

A search results ranking method that uses semantic features and a cluster coherence measure is introduced in this paper. The quality of the returned search results is improved by grouping semantically related texts into clusters displayed in descending cluster size order. First the term-document matrix is constructed where the documents correspond to individual texts. Then, nonnegative matrix factorization (NMF) is used to group the texts into semantically related clusters. Only those clusters whose coherence is greater than a threshold value are displayed. In this way trending conceptually similar texts that re-occur in the input of multiple users are identified. The advantage of this approach compared to other methods consists in the fact that the clusters in the approach introduced in this paper are computed by semantic similarity and not only by texts counters.
Equivalent circuit modeling of the dielectric properties of rubber wood at low frequency (2000)

Dielectric properties of rubber wood were studied at various moisture contents and grain directions at low frequencies from to lo5 Hz.Results showed that the moisture content of wood affected the dielectric properties considerably.Dielectric data at different anisotropic directions, i.e., longitudinal, radial, and tangential and at various moisture contents were modeled using universal capacitance.The equivalent circuits for different dielectric processes observed in wood were expressed by the combinations of diffusive, quasi-dc elements together with nondispersive capacitance and resistance.Three equivalent circuits for wood with moisture contents-a) above fiber saturation point, b) below fiber saturation point, and c) very low moisture content or oven-dried wood-are obtained for three grain directions.The experimental data are in close agreement with the value obtained from equivalent circuit.
성형직후(成形直後) 건조환경(乾燥環境)이 시멘트 모르터의 강도(强度)에 미치는 영향(影響) (1991)

This study was carried out to research the strength drop of concrete in dry environment. The mixing ratio of cement-fine aggregate was 1 : 1, 1 : 2, 1: 3 and 1 : 4.
The curing was compared standard curing with dry curing immediately after casting. It is analysis of strength change by water-proof mixing. The curing age of cement mortar was 3days, 7days, l4days and 28days.
The result obtained from this study are summarized as follows.
1. The compressive and bending strength change by increasing the curing age, dry curing mortar the increasing rate of strength was decreased than standard curing mortar.
2. The compressive and bending strength change in early curing, strength difference between standard curing mortar and dry curing mortar was gradually closed by increasing the W/C.
3. The dry curing mortar was decreased than standard curing mortar in decreasing rate of compressive and bending strength by increasing the W/C.
4. The compressive strength of water-proof mortar in early curing, liquid water-proof mortar was shown high strength in dry curing than standard curing. The powder and liquid water-proof mortar have a small effect in dry environment. The liquid water-proof mortar was high strength without relation change of curing age in dry environment than standard curing.
5. The compressive strength of liquid water-proof mortar in poverty mix, dry curing was shown high strength than standard curing.
6. The bending strength was increased than compressive strength by decreasing the volume of cement in early curing. The increasing rate of bending strength was decreased to compressive stength by increasing the curing age.
CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease (2015)

The continuous recirculation of mature lymphocytes and their entry into the peripheral lymph nodes are crucial for the development of an immune response to foreign antigens. Occasionally, the entry and the subsequent response of T lymphocytes in these sites lead to severe inflammation and pathological conditions. Here, we characterized the tetraspanin molecule, CD151, as a regulator of T cell motility in health and in models of inflammatory bowel disease. CD151 formed a cell surface complex with VLA-4 and LFA-1 integrins, and its activation led to enhanced migration of T cells. Picomolar levels of CCL2 that were previously shown to inhibit T-cell migration to lymph nodes suppressed CD151 expression and dissociated CD151-integrin complexes in T lymphocytes, resulting in attenuated migration toward T-cell attractant chemokines. To directly inhibit CD151 function, a truncated CD151 peptide fragment mimicking of the CD151 extracellular loop was designed. CD151 extracellular loop inhibited T-cell migration in vitro and in vivo and attenuated the development of dextrane sulfate sodium-induced colitis. Thus, CD151 is a key orchestrator of T cell motility; interference with its proper function results in attenuated progression of inflammatory bowel disease.
Design and development of wideband and dual-band microstrip antennas (1999)

A study of the wideband and dual-band characteristics of single- and double-notched rectangular patch antennas is presented. A comparative study of the experimental results employing coax, microstrip, aperture-coupled and electromagnetically coupled feed techniques has been made for increased bandwidth and improved crosspolar level. Optimum coax-fed location, input resonant resistance and notch parameters are estimated using the transmission-line model. The experimental radiation patterns were compared with simulated and theoretical patterns and found to be in good agreement. The maximum measured impedance bandwidths of 26.6% in band 1 and 31.7% in band 2 have been achieved for coax-fed single-notched patches. A double-layered double-notched aperture coupled (composite) patch antenna was also designed, and further improvement in impedance bandwidth of 39% was achieved without significant degradation in radiation characteristics. From the measured and calculated results it can be seen that single- or double-notched composite patches can be designed to yield wide- and dual-band operations suitable for mobile communications.
Polyamides of 1,4‐cyclohexanebis(methylamine) (1965)

Abstract Polyamides of both cis ‐ and trans ‐1,4‐cyclohexanebis(methylamine) with aliphatic dicarboxylic acids and copolyamides of trans ‐1,4‐cyclohexanebis(methylamine) with p ‐xylene‐α,α′‐diamine were prepared in order to discover the effect of cycloalkane rings on melting point. Analogous polyamides of p ‐xylene‐α,α′‐diamine were prepared for comparison. The polyamides of trans ‐1,4‐cyclohexanebis(methylamine) had higher melting points than the analogous polyamides of p ‐xylene‐α,α′‐diamine. This result is believed to be due to the slightly contracted conformation which trans ‐1,4‐cyclohexanebis(methylamine) can adopt in the polymer chain. The polyamides of cis ‐1,4‐cyclohexanebis(methylamine) melted lower than those of the trans isomer. The lower symmetry of the cis ‐diamine accounts for this result. The melting points of the copolyamides of trans ‐1,4‐cyclohexanebis(methylamine) and p ‐xylene‐α,α′‐diamine were higher than expected. It is suggested that these compositions are examples of partially isomorphous copolyamides.
Ri T-DNA from Agrobacterium rhizogenes : a source of genes having applications in rhizosphere biology and plant development, ecology and evolution (1989)

International audience
The Effect of Lime Addition on the Setting Time and Strength of Ambient Cured Fly Ash Based Geopolymer Binder (2016)

One of the limitations of geopolymer as the alternative binders in concrete is the necessity of heat curing. This study aimed to produce fly ash geopolymer binder subjected to ambient curing by adding a small proportion of lime and varying the activator dosage. The Class F fly ash from Mpanau coal-fired power plant was mixed with alkaline solution consists of sodium silicate and sodium hydroxide with Na2O dosage of 5%, 7%, and 9%. To achieve ambient cured paste, 8%, 9%, and 10% slaked lime was added as the substitute for the fly ash. The setting time test was conducted for each mix and the compressive strength was performed at age of 7, 14 and 28 days. The test result shows that the setting time of the fly ash based geopolymer paste can be controlled by adding a small proportion of slaked lime. The addition of lime increased strength but decreased the setting time.
T-Type Ca<sup>2+</sup>Current Properties Are Not Modified by Ca<sup>2+</sup>Channel β Subunit Depletion in Nodosus Ganglion Neurons (1997)

At the molecular level, our knowledge of the low voltage-activated Ca 2+ channel (T-type) has made little progress. Using an antisense strategy, we investigated the possibility that the T-type channels have a structure similar to high voltage-activated Ca 2+ channels. It is assumed that high voltage-activated channels are made of at least three components: a pore forming α 1 subunit combined with a cytoplasmic modulatory β subunit and a primarily extracellular α 2 δ subunit. We have examined the effect of transfecting cranial primary sensory neurons with generic anti-β antisense oligonucleotides. We show that in this cell type, blocking expression of all known β gene products does not affect T-type current, although it greatly decreases the current amplitude of high voltage-activated channels and modifies their voltage dependence. This suggests that β subunits are likely not constitutive of T-type Ca 2+ channels in this cell type.
Yb/Er Integrated optics amplifiers on phosphate glass in single and double pass configurations. (1995)

In the past few years, fiber optics amplifiers have become ubiquitous in the new 1550 nm telecom systems. Integrated optics could lower cost and size of amplifiers, but it demands suitable substrates to host efficient and short amplifying waveguides. So far, devices showing net gain at 1550 nm were based on silicate glasses1,2. Rare-earth doped phosphate glasses offer better prospects, because they retain good spectroscopic properties at higher dopant concentrations.
Using Ethernet Technology for In-Vehicle's Network Analysis (2013)

During the last years, Ethernet increasingly became the most extensively used local area networking (LAN) technology. It became also attractive for several other fields of application like industry, avionics, automotive and telecommunication. The prolonged application of this technology is principally due to its considerable assets like reduced cost, expandability and flexibility. However, Ethernet has been improved to fulfill with the specific conditions of several application fields, mainly in automotive context, is our first purpose. This paper provides firstly a general overview of Ethernet in the automotive field (especially on diagnosis process) comparing it to earliest automotive networks. Then, we will present CableFish, our optimized and high performance network analyzer. CableFish gives a real time analysis for all packets circulating between several ECUs (without loss) and allows in-car diagnosis due to the newly added HSFZ protocol.