gebhart/patrepeval huggingface dataset:
Human-Computer Interaction Using Emotion Recognition from Facial Expression (2011)

This paper describes emotion recognition system based on facial expression. A fully automatic facial expression recognition system is based on three steps: face detection, facial characteristic extraction and facial expression classification. We have developed an anthropometric model to detect facial feature points combined to Shi&Thomasi method. The variations of 21 distances which describe the facial features deformations from the neutral face, were used to coding the facial expression. Classification step is based on SVM method (Support Vector Machine). Experimental results demonstrate that the proposed approach is an effective method to recognize emotions through facial expression with an emotion recognition rate more than90% in real time. This approach is used to control music player based on the variation of the emotional state of the computer user.
A low-power CMOS thyristor based delay element with programmability extensions (2009)

This paper presents a low-power CMOS thyristor based delay element for inclusion in standard cell ASIC libraries, and a reconfigurable delay element designed for reconfigurable devices. Our design is based on a basic delay element, which serves as a buffer which has been specially designed to have a fixed propagation delay. We present leakage power optimizations, which when applied to the circuit reduces the on-state leakage power consumption by more than 99%, while reducing the off-state leakage power by roughly 96%. We have created delay elements with delay lengths of 4, 5, 7, 9, 11, and 17 ns for inclusion in a standard cell library targeting the IBM 0.13 μm technology. The delay element is then further extended to introduce a programmability feature which allows the delay to be varied. Two reconfigurable delay elements are then added to the delay element standard cell library. The first can be configured for delays of 4, 5, or 7 ns, while the second can be programmed for delays of 9, 11, or 17 ns. Finally, potential uses of the circuits in application specific, as well as reconfigurable systems are explored.
Renal Elimination of Sclerostin Increases With Declining Kidney Function (2013)

Increased sclerostin serum levels in CKD patients are not due to decreased renal elimination. On the contrary, renal elimination increases with declining kidney function. Whether this has consequences on antisclerostin antibody dosing, efficacy, or safety in patients with CKD remains to be determined.
RC2-a living lab for cloud computing (2010)

In this paper we present our experience in building the Research Compute Cloud (RC2), a cloud computing platform for use by the worldwide IBM Research community. Within eleven months of its official release RC2 has reached a community of 631 users spanning 34 countries, and serves on average 350 active users and 1800 active VM instances per month. Besides offering a utility computing platform across a heterogeneous pool of servers, RC2 aims at providing a living lab for experimenting with new cloud technologies and accelerating their transfer to IBM products. This paper describes our experience in designing and implementing a flexible infrastructure to enable rapid integration of novel ideas while preserving the overall stability and consumability of the system. 1
Introduction of a fully portable, body-mounted emergency medical information system (2002)

InterVision Systems Inc. has developed a "wearable" computer system for use by Walter Reed Army Institute of Research. The system will be used to access medical information, to support remote primary care, and for remote diagnostic consultation. The system consists of a small 4/spl times/4/spl times/3-inch chassis that houses the CPU, interface boards, battery mount and a panel of standard I/O ports. The system comprises a 486SLC/25 MHz computer bus, 4, 8 or 12 MB RAM, a 170 MB removable hard drive for a type III PCMCIA slot, a type II PCMCIA slot, voice actuation software and hardware, and a miniature wrist-mounted keyboard. The miniature VGA CRT is mounted on a head band, or may be mounted on the wrist, and displays text, graphics or information relayed from the medical information system or from the medical consultant.
Approaches to Fault-Tolerant Mobile Agent Execution (2001)

Fault tolerance is fundamental to the further development of mobile agent applications. It ensures that the agent arrives at its destination and thus prevents a partial or complete loss of the agent. This paper surveys the current approaches to fault-tolerant mobile agent execution. Most of these approaches are based on replication. We propose a classification into temporal-replication-based and spatial-replication-based approaches and discuss the advantages and disadvantages of these approaches. 1
Specific capture and temperature-mediated release of cells in an aptamer-based microfluidic device (2012)

Isolation of cells from heterogeneous mixtures is critically important in both basic cell biology studies and clinical diagnostics. Cell isolation can be realized based on physical properties such as size, density and electrical properties. Alternatively, affinity binding of target cells by surface-immobilized ligands, such as antibodies, can be used to achieve specific cell isolation. Microfluidics technology has recently been used in conjunction with antibody-based affinity isolation methods to capture, purify and isolate cells with higher yield rates, better efficiencies and lower costs. However, a method that allows easy release and collection of live cells from affinity surfaces for subsequent analysis and detection has yet to be developed. This paper presents a microfluidic device that not only achieves specific affinity capture and enrichment, but also enables non-destructive, temperature-mediated release and retrieval of cells. Specific cell capture is achieved using surface-immobilized aptamers in a microchamber. Release of the captured cells is realized by a moderate temperature change, effected via integrated heaters and a temperature sensor, to reversibly disrupt the cell-aptamer interaction. Experimental results with CCRF-CEM cells have demonstrated that the device is capable of specific capture and temperature-mediated release of cells, that the released cells remain viable and that the aptamer-functionalized surface is regenerable.
BiCMOS circuit technology for high-speed DRAMs (1993)

A BiCMOS circuit technology featured by a novel bit-line sense amplifier has been developed. The bit-line sense amplifier is composed of a BiCMOS differential amplifier, the impedance-converting means featured by the CMOS current mirror circuit or the clocked CMOS inverter between the bit line and the base node of the BiCMOS differential amplifier, and a conventional CMOS flip-flop. This technology can reduce the access time to half that of a conventional CMOS DRAM access time. Applied to a 1-kb DRAM test chip, a new BiCMOS circuit technology was successfully verified. Furthermore, the sensitivity and area penalty of the new BiCMOS bit-line sense amplifier and future applications to megabit DRAMs are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Robust Segmentation of Unconstrained Online Handwritten Documents. (2004)

A segmentation algorithm, which can detect different regions of a handwritten document such as text lines, tables and sketches will be extremely useful in a variety of applications such as retrieval, translation and genre classification. However, this task is extremely challenging for handwritten documents, which vary considerably in their structure and content. In this paper, we describe a robust segmentation method to detect the regions in an unstructured on-line handwritten document. We utilize the temporal information in on-line documents along with its spatial layout to improve the segmentation results. The properties of handwritten strokes are computed using a spline-based representation. We compute the most likely segmentation of the handwritten page using a Stochastic Context Free Grammar based parser. The regions considered in this work include paragraphs, text lines, words, and non-text regions.
Toward a physical map of the genome of the nematode <i>Caenorhabditis elegans</i> (1986)

A technique for digital characterization and comparison of DNA fragments, using restriction enzymes, is described. The technique is being applied to fragments from the nematode Caenorhabditis elegans (i) to facilitate cross-indexing of clones emanating from different laboratories and (ii) to construct a physical map of the genome. Eight hundred sixty clusters of clones, from 35 to 350 kilobases long and totaling about 60% of the genome, have been characterized.
Membrane-disorganizing property of polymyxin B nonapeptide (1986)

The possibility of improving the antibacterial activities of drugs normally excluded by Gram-negative bacteria with polymyxin B nonapeptide (PMBN) has been explored. In vitro, PMBN rendered clindamycin, erythromycin, novobiocin, rifampicin and vancomycin very active against a number of Gram-negative enteric bacteria. The drug also sensitized the previously resistant bacterial strains to human, mouse or guinea pig serum. However, parenterally administered PMBN failed to influence bacterial growth in chambers implanted into mice and guinea pigs. It was also ineffective in experimental septicaemia at a dose of up to 200 mg/kg or when combined with antibiotics with which it interacted synergistically in vitro.
Optical properties of GaN grown over SiO2 on SiC substrates by molecular beam epitaxy (1998)

We investigate the optical properties of GaN grown over SiO2 on SiC substrates by electron cyclotron resonance assisted molecular beam epitaxy. The photoluminescence spectra and refractive index of GaN were compared for GaN/SiO2/SiC and GaN/SiC. Strong band-edge luminescence was observed at 3.40 eV from the GaN on both SiO2/SiC and on SiC. No defect-related yellow luminescence was observed. The refractive index of GaN at 1.96 eV (632.8 nm) was measured at 2.22 and 2.24 for GaN/SiO2/SiC and GaN/SiC, respectively.
Exchange Transfusion and Leukapheresis in Pediatric Patients with AML With High Risk of Early Death by Bleeding and Leukostasis (2015)

Our data confirm the high risk of bleeding/leukostasis in patients with hyperleukocytosis. ET/LPh shows a trend toward reduced ED rate due to bleeding/leukostasis and is recommended at WBC >200,000/μl, and in FAB M4/M5 even at lower WBC.
On Acylhydrazones and 1,2,3-Thiadiazoles (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOn Acylhydrazones and 1,2,3-ThiadiazolesCharles D. Hurd and Raymond I. MoriCite this: J. Am. Chem. Soc. 1955, 77, 20, 5359–5364Publication Date (Print):October 1, 1955Publication History Published online1 May 2002Published inissue 1 October 1955https://pubs.acs.org/doi/10.1021/ja01625a047https://doi.org/10.1021/ja01625a047research-articleACS PublicationsRequest reuse permissionsArticle Views980Altmetric-Citations181LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of Chiral Quaternary Ammonium Salts on (salen)Mn-Catalyzed Epoxidation of cis-Olefins. A Highly Enantioselective, Catalytic Route to Trans-Epoxides (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of Chiral Quaternary Ammonium Salts on (salen)Mn-Catalyzed Epoxidation of cis-Olefins. A Highly Enantioselective, Catalytic Route to Trans-EpoxidesSukbok Chang, Jennifer M. Galvin, and Eric N. JacobsenCite this: J. Am. Chem. Soc. 1994, 116, 15, 6937–6938Publication Date (Print):July 1, 1994Publication History Published online1 May 2002Published inissue 1 July 1994https://pubs.acs.org/doi/10.1021/ja00094a059https://doi.org/10.1021/ja00094a059research-articleACS PublicationsRequest reuse permissionsArticle Views2985Altmetric-Citations133LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Electron Probe Analysis for Iodine in Human Thyroid and Parathyroid Glands, Normal and Neoplastic<xref ref-type="fn" rid="FN2">2</xref> (1971)

Iodine analysis in human thyroid and parathyroid tissue, normal and neopiastic, was performed using the electron probe X-ray microanalyzer. Iodine within the limit of detection, >0.04%, was found in the follicular colloid of normal thyroid and thyroid adenomas, but not in cells lining the follicles. Paraffin embedding and hematoxylin and eosin staining did not diminish the detectability. With one exception, there was no iodine in the colloid-like material or cells of parathyroid glands. There was none in parathyroid adenomas, the colloid or cells of thyroid carcinomas, or the amyloid or cells of medullary carcinoma of the thyroid.
Molecular Cloning and Characterization of NESP55, a Novel Chromogranin-like Precursor of a Peptide with 5-HT1B Receptor Antagonist Activity (1997)

The chromogranins comprise a class of acidic proteins that are secreted from large dense core vesicles and expressed in neuronal and endocrine tissues. We describe here the molecular characterization of NESP55 (neuroendocrine secretory protein of Mr 55,000), a novel member of the chromogranins. Several NESP55 cDNA clones were isolated from bovine chromaffin cell libraries. The cDNA sequence of NESP55 totals 1499 nucleotides. All of the clones that were isolated contained in their 3'-untranslated mRNA a sequence that was homologous to exon 2 of the G-protein Gsalpha. The open reading frame encodes for an acidic and hydrophilic protein of 241 amino acids with a predicted molecular mass of 27,494 Da. An antiserum directed against the C terminus of NESP55 labeled a band of Mr 55,000 with an acidic pI ranging from 4.4 to 5.2 in one- and two-dimensional immunoblots of secretory proteins from chromaffin granules. NESP55 is localized within the cell to the large dense secretory vesicles and is expressed, apart from the adrenal medulla, in the anterior and posterior pituitary and various regions of the brain. For the physiological function, one interesting factor has emerged. NESP55 is proteolytically processed within the chromaffin granule to smaller peptides that might be physiologically active. One tetrapeptide, Leu-Ser-Ala-Leu (LSAL), present in the NESP55 sequence and flanked by arginine residues suitable for cleavage by prohormone convertases, has been identified recently as an endogenous antagonist of the serotonergic 5-HT1B receptor subtype. Alterations in the serotonergic system are thought to play an important role in mental disorders, especially depression, and might be related to abnormal ethanol consumption. It is tempting to speculate that increased expression of NESP55 or its proteolytically derived peptide LSAL might contribute to the pathophysiology of the serotonergic transmission.
Effects of FDI on China Based on the Fuzzy Mathematics (2009)

The international direct investment theory is one of domains which develop quickly in the international economics after the Second World War. Comparing with that obviously, the research of influencing factors about FDI (Foreign Direct Investment) develops very slowly. For a long time, FDI was thought to exert very important function to the economical increase of the host country, but in recent years, some negative influences occur. Base on some scholars’ theoretical analysis, in this article, we utilize the method of fuzzy mathematics to comprehensively analyze the influencing factors of FDI on the host country, and translate the result into the data which can be directly compared to directly evaluate FDI.
The Endogenous and Cell Cycle-dependent Phosphorylation of tau Protein in Living Cells: Implications for Alzheimer’s Disease (1998)

In Alzheimer's disease the neuronal microtubule-associated protein tau becomes highly phosphorylated, loses its binding properties, and aggregates into paired helical filaments. There is increasing evidence that the events leading to this hyperphosphorylation are related to mitotic mechanisms. Hence, we have analyzed the physiological phosphorylation of endogenous tau protein in metabolically labeled human neuroblastoma cells and in Chinese hamster ovary cells stably transfected with tau. In nonsynchronized cultures the phosphorylation pattern was remarkably similar in both cell lines, suggesting a similar balance of kinases and phosphatases with respect to tau. Using phosphopeptide mapping and sequencing we identified 17 phosphorylation sites comprising 80-90% of the total phosphate incorporated. Most of these are in SP or TP motifs, except S214 and S262. Since phosphorylation of microtubule-associated proteins increases during mitosis, concomitant with increased microtubule dynamics, we analyzed cells mitotically arrested with nocodazole. This revealed that S214 is a prominent phosphorylation site in metaphase, but not in interphase. Phosphorylation of this residue strongly decreases the tau-microtubule interaction in vitro, suppresses microtubule assembly, and may be a key factor in the observed detachment of tau from microtubules during mitosis. Since S214 is also phosphorylated in Alzheimer's disease tau, our results support the view that reactivation of the cell cycle machinery is involved in tau hyperphosphorylation.
Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing. (1990)

cDNA clones encoding three novel tropomyosins, termed TMBr-1, TMBr-2, and TMBr-3, were isolated and characterized from a rat brain cDNA library. All are derived from a single gene, which was previously found to express striated muscle alpha-tropomyosin and a number of other tropomyosin isoforms via an alternative splicing mechanism (N. Ruiz-Opazo and B. Nadal-Ginard, J. Biol. Chem. 262:4755-4765, 1987; D. F. Wieczorek, C. W. J. Smith, and B. Nadal-Ginard, Mol. Cell. Biol. 8:679-694, 1988). The derived amino acid sequences revealed that TMBr-1 contains 281 amino acids, TMBr-2 contains 251 amino acids, and TMBr-3 contains 245 amino acids. All three proteins contain a region that is identical to amino acids 81 through 258 of skeletal muscle alpha-tropomyosin. TMBr-1 is identical to striated muscle alpha-tropomyosin from amino acids 1 through 258 but contains a novel COOH-terminal region from amino acids 259 through 281. TMBr-2 and TMBr-3 both contain identical NH2-terminal sequences from amino acids 1 through 44 which were found to be expressed from a novel promoter. TMBr-3 contains the same COOH-terminal region as TMBr-1, whereas TMBr-2 contains a second novel COOH-terminal region. The genomic organization of the exons encoding TMBr-1, TMBr-2, and TMBr-3 were determined. These studies revealed a previously uncharacterized promoter located in the internal region of the alpha-TM gene as well as two novel COOH-terminal coding exons. The alpha-TM gene is a complex transcription unit containing 15 exons including two alternative promoters, two internal mutually exclusive exon cassettes, and four alternatively spliced 3' exons that encode four different COOH-terminal coding regions. A total of nine distinct mRNAs are known to be expressed from the alpha-TM gene in a cell type-specific manner in tissues such as striated muscle, smooth muscle, kidney, liver, brain, and fibroblasts. The mRNAs encoding TMBr-1, TMBr-2, and TMBr-3 were found to be expressed only in brain tissue, with TMBr-3 being expressed at much greater levels than TMBr-1 and TMBr-2. The individual structural characteristics of each brain alpha-tropomyosin isoform and their possible functions are discussed.
Synthesis and Structural Characterization of the Sodium Salt of a New Sulfonate-containing Water Soluble N-Donor Ligand⎯ Self-assembly in the Solid State by π−π Stacking Interactions (2006)

The synthesis, spectroscopic characterization, and X-ray crystal structure of the sodium salt of a new sulfonated water-soluble ligand, sodium 2-(2-pyridin-2-yl-ethylamino)-benzenesulfonate (L) are described. Compound L crystallizes in the centrosymmetric space group Pbcn, orthorhombic, a=31.930(13) A, b=7.153(3) A,c=14.193(6) A, alpha=90.00, beta=90.00, gamma=90.00, V=3220(2) A(3), Z=9. pi-pi stacking contacts involving interactions between the pi-donor benzene and the pi-acceptor pyridine systems reinforce and direct the self-assembly of the structural motifs in the solid state.
Microparallelism and high-performance protein matching (1995)

The Smith-Waterman algorithm is a computationally-intensive string-matching operation that is fundamental to the analysis of proteins and genes. In this paper, we explore the use of some standard and novel techniques for improving its performance. We begin by tuning the algorithm using conventional techniques. These make modest performance improvements by providing efficient cache usage and inner-loop code. One novel technique uses the z-buffer operations of the Intel i860 architecture to perform 4 independent computations in parallel. This achieves a five-fold speedup over the optimized code (six-fold over the original). We also describe a related technique that could be used by processors that have 64-bit integer operations, but no z-buffer. Another new technique uses floating-point multiplies and adds in place of the standard algorithm's integer additions and maximum operations. This gains more than a three-fold speedup on the IBM POWER2 processor. This method doesn't give the identical answers as the original program, but experimental evidence shows that the inaccuracies are small and do not affect which strings are chosen as good matches by the algorithm.