gebhart/patrepeval huggingface dataset:
Radiographic Detection of Single Strut Leg Separations as a Putative Basis for Prophylactic Explantation of Björk‐Shiley Convexo‐Concave Heart Valves (1996)

Cineradiography, using higher kVp and two or more specified profiles for each outlet strut leg, was used to evaluate Björk-Shiley convexo-concave (C/C) heart valves with epidemiologically defined > 0.1% per year estimated fracture rates. Among 828 mitral valves, eight radiographs were assessed as definite single leg separations (SLS) and 23 were read as probable SLS. Explantation confirmed SLS in 24 valves; 4 probables were false positives, and 3 patients with probable SLS ratings decided against explantation. Four patients with SLS died, an operative mortality of 14%. Only 23 mitral and 6 aortic valves receiving ratings ranging from apparently normal to suspicious have become available for verification; 1 rated apparently normal was found to have a SLS. Two patients experienced fatal fractures and 1 SLS valve was explanted 3 to 15 months after apparently normal x-ray studies; it cannot be known if a SLS was or was not present at the time of these examinations. As 97% of negatively rated valves remain in situ, the sensitivity of the test is similarly not known. Only 1 SLS has been detected among 136 aortic valves. Uncertainty about test accuracy and SLS progression condition the clinical utility of radiographic SLS detection, particularly with respect to assurance from apparently normal readings. However, radiographic identification of an SLS substantially enhances epidemiologically derived risk categorization as a basis for consideration of prophylactic replacement for the approximately 12,000 valves with a > 0.1% estimated annual fracture risk, currently thought to be implanted in living patients.
Inventory of forest biomass in Brazilian Amazon: a local approach using airborne P-band SAR data (2002)

The objective of this study is to explore the use of airborne P-band SAR polarimetric data, to stratify biomass by primary and secondary vegetation typology. To ensure that different landscapes of Amazon upland forest are represented, a test-site located in the lower Rio Tapajos region, Pari State, was selected. The backscatter signals derived from the complex image of the P-band SAR were correlated with field data obtained from a forest inventory, for different physiognomic-structural aspects of the tropical rainforest The estimation of above-ground biomass for these forest types was modeled by DBH and total height measurements, including the use of general allometric equations. Statistical regression models were applied to establish the relationship between biomass and radar data at HH, HV and VV polarization. The overall objective of this P-band experiment is to improve the regional monitoring process of biomass dynamics as well as landscape changes, due to human action.
Effect of joint contamination on the quality of butt-fused high-density polyethylene (HDPE) pipe joints (2002)

Butt fusion is an effective method for joining high-density polyethylene (HDPE) pipe on job sites. However, there is lack of quantitative methods to evaluate pipe joint quality. The objective of this study was to develop such a quantitative approach to determine the effect of joint contamination on the quality of the fused joints. The study included testing a total of 21 butt-fused HDPE pipe joints that were made under different dust conditions. The results of the tests were then used to determine the effect of dust contamination on the quality of the fused joints. Microscopic examination of the fracture surfaces of the test specimens showed that not all the contaminants at the welding interface were squeezed out into the beads formed during the fusion process. Four failure modes were identified and a failure criterion was established to categorize the quality of a fused joint into four grades: bad, poor, good, and excellent. Among the properties of the materials considered, tensile energy to break (TEB) and maximum strain were found to be the most acceptable parameters for distinguishing between joints of different quality. Furthermore, the results showed that under optimum joining conditions, the quality of butt-fused joints can be as good as that of the parent pipe.Key words: polyethylene pipe, butt fusion, joint contamination, tensile energy to break, failure criterion.
A strong antibody response to the periplasmic C-terminal domain of the OmpA protein of Escherichia coli is produced by immunization with purified OmpA or with whole E. coli or Salmonella typhimurium bacteria (1990)

We produced in Bacillus subtilis the complete, as well as the N-terminal two-thirds, OmpA protein of Escherichia coli (called here Bac-OmpA and Bac-OmpA-dN, respectively). These Bac-OmpA proteins were used to examine the immunological properties of different parts of OmpA, free of lipopolysaccharide and other components of the outer membrane. The full-length Bac-OmpA was indistinguishable from the authentic protein isolated from E. coli (Coli-OmpA) both as immunogen and as antigen in enzyme immunoassay (EIA). The N-terminal Bac-OmpA-dN was a poor immunogen which gave rise to significantly lower titers of anti-OmpA antibody than did the full-length OmpA preparations. When used as an antigen in EIA, the Bac-OmpA-dN detected anti-OmpA antibody in serum samples from animals immunized with the full-length OmpA much less efficiently than did either Bac-OmpA or Coli-OmpA. The periplasmic C-terminal domain therefore appears to be an immunodominant epitope of the purified OmpA protein. Also, when rabbits and mice were immunized with intact, live or dead E. coli, the antibody response detected by EIA with the full-length protein, Bac-OmpA, was much stronger than that detected with the N-terminal two-thirds, Bac-OmpA-dN. Similar results were obtained with the OmpA of Salmonella typhimurium. Because the ompA gene of enterobacteria is highly conserved, the Bac-OmpA might be useful as a group-specific EIA antigen to diagnose diseases caused by members of the family Enterobacteriaceae.
Efficient one-step melt-compounding of copolyetheramide/pristine clay nanocomposites using water-injection as intercalating/exfoliating aid (2011)

Polyether-block-amide (PEBA) /clay nanocomposites were prepared water-assisted by twin-screw extrusion. Both organomodified and pristine (i.e. purified but non-modified) montmorillonite clays were used. A high-pressure differential scanning calorimetry analysis carried out in the processing conditions demonstrated that PEBA/water blend exhibits some miscibility and that amide blocks and water behave as a single phase. In addition to a significant decrease of the melting temperature, water injected into the melt plays a key role among the filler dispersion and prevents the matrix from degradation during melt-extrusion. This process enables the compounding of pristine clay-based nanocomposites whose dispersion state is high enough for the resulting mechanical performances in tension to be at least equivalent to what is reached with organomodified clay. Effects of the nanofiller dispersion onto the macromolecules' mobility are detailed and fracture mechanisms are identified for the various structures.
The influence of the site of infection on the immune response to group A streptococci (1970)

The immune response after streptococcal infection of the skin and of the upper respiratory tract (URT) was studied prospectively in a group of normal children, ages 3-6 yr. The children were examined and cultures for group A streptococci were obtained weekly from the throat, nose, and skin lesions (when present). Paired sera were collected at the beginning and end of the study, and the changes in antibody titers were measured for three different streptococcal antigens: streptolysin O, deoxyribonuclease B (DNAse B), and nicotinamide adenine dinucleotidase (NADase). The findings suggest that in contrast to infection of the URT antibody response to streptolysin O is relatively feeble after streptococcal infection which is limited to the skin. The response to NADase is also poor after cutaneous infection. Antibody responses to DNAse B are generally good regardless of the site of the infection. These and other studies indicate that anti-DNAse B is the antibody of choice in studying streptococcal infection of the skin and its complications.
Dynamic holographic interconnects with analog weights in photorefractive crystals (1990)

A photorefractive interconnect system with coherently erasable synapses (PISCES) is described. Comparing holographic erasure by intensity and phase modulation of the writing beams, we find that the timeaverage technique is most amenable to system implementation. Calculations derived from a simple model of diffraction show that it is possible to find configurations that maximize the interconnection capacity. The PISCES includes Fresnel zone plates for spot array generation, amplitude and phase spatial light modulators based on liquid crystal technology, and detector arrays, in addition to the photorefractive crystal. Alternatives for each of these elements are described.
Development of dimethyl sulfoxide biosensor using a mediator immobilized enzyme electrode (2003)

A mediator immobilized dimethyl sulfoxide (DMSO) sensor using DMSO reductase (DMSO-R) was constructed. Methyl viologen (MV) was used as a mediator and immobilized on a glassy carbon (GC) electrode with Nafion polymer. DMSO-R from Rhodobacter sphaeroides f. sp. denitrificans was retained by a dialysis film on the modified GC electrode. The amperometric signal in response to DMSO was observed. The linear range of the calibration curve for DMSO was between 0 and 600 microM. The response time was within 100 s and the relative standard deviation was 4% at 200 microM DMSO (n = 4). To eliminate the background noise derived from oxygen in samples, the glucose oxidase-catalase retained DMSO sensor was also examined.
Presentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processing (1998)

Mouse CD1(mCD1) molecules have been reported to present two types of antigens: peptides or proteins and the glycolipid alpha-galactosylceramide. Here, we demonstrate that a protein antigen, chicken ovalbumin (Ova), must be processed to generate peptides presented by mCD1 to CD8(+) T cells. The processing and mCD1-mediated presentation of chicken Ova depend on endosomal localization because inhibitors of endosomal acidification and endosomal recycling pathways block T cell reactivity. Furthermore, a cytoplasmic tail mutant of mCD1, which disrupts endosomal localization, has a greatly reduced capacity to present Ova to mCD1 restricted cells. Newly synthesized mCD1 molecules, however, are not required for Ova presentation, suggesting that molecules recycling from the cell surface are needed. Because of these data showing that mCD1 trafficks to endosomes, where it can bind peptides derived from exogenous proteins, we conclude that peptide antigen presentation by mCD1 is likely to be a naturally occurring phenomenon. In competition assays, alpha-galactosylceramide did not inhibit Ova presentation, and presentation of the glycolipid was not inhibited by excess Ova or the peptide epitope derived from it. This suggests that, although both lipid and peptide presentation may occur naturally, mCD1 may interact differently with these two types of antigens.
Video brainstorming and prototyping (1999)

This tutorial is designed for HCI designers and researchers interested in learning specific techniques for using video to support a range of participatory design activities. Based on a combination of lectures, video demonstrations and hands-on exercises, the tutorial will give participants practical experience using video to observe users in laboratory and field settings, to analyze multimedia data, to explore and capture design ideas (video brainstorming), to simulate interaction techniques with users (Wizard-of-oz and video prototyping) and to present video-based design ideas to users and managers. Participants will gain experience shooting video and will address practical issues such as maintaining video archives and ethical issues such as obtaining informed consent. Although these video techniques are applicable in a variety of design settings, the emphasis here is on participatory design, using video as a tool to help users, researchers and designers gather and communicate design ideas.
Enhanced fibronectin receptor expression in Rous sarcoma virus-induced tumors. (1988)

The mechanisms by which cells acquire the capacity to invade interstitial connective tissues during malignancy are as yet uncertain. Since the fibronectin receptor complex has been implicated in transient, developmentally regulated steps of migration and morphogenesis in embryogenesis, we examined whether this receptor might be reexpressed at elevated levels in tumors. Immunofluorescence revealed increased expression of the receptor throughout frozen sections of Rous sarcoma virus-induced tumors in chickens, and expression was enhanced 4.7-fold after such malignant transformation of fibrocytes in vivo. Frozen thin sections showed that the increased antigen was localized diffusely in the plasma membrane. Western immunoblotting with monoclonal antibodies and immunoprecipitation analyses indicated that the tumor cell receptor contained all three known avian receptor subunits, i.e., Bands 1, 2, and 3. This type of induction of a key extracellular matrix receptor involved in cell migration may be a prerequisite for tumor cell invasion.
Adaptive Control of Exoskeleton Robots for Periodic Assistive Behaviours Based on EMG Feedback Minimisation (2016)

In this paper we propose an exoskeleton control method for adaptive learning of assistive joint torque profiles in periodic tasks. We use human muscle activity as feedback to adapt the assistive joint torque behaviour in a way that the muscle activity is minimised. The user can then relax while the exoskeleton takes over the task execution. If the task is altered and the existing assistive behaviour becomes inadequate, the exoskeleton gradually adapts to the new task execution so that the increased muscle activity caused by the new desired task can be reduced. The advantage of the proposed method is that it does not require biomechanical or dynamical models. Our proposed learning system uses Dynamical Movement Primitives (DMPs) as a trajectory generator and parameters of DMPs are modulated using Locally Weighted Regression. Then, the learning system is combined with adaptive oscillators that determine the phase and frequency of motion according to measured Electromyography (EMG) signals. We tested the method with real robot experiments where subjects wearing an elbow exoskeleton had to move an object of an unknown mass according to a predefined reference motion. We further evaluated the proposed approach on a whole-arm exoskeleton to show that it is able to adaptively derive assistive torques even for multiple-joint motion.
PM IRRAS Investigation of Thin Silica Films Deposited on Gold. Part 1. Theory and Proof of Concept (2007)

Polarization modulation infrared reflection absorption spectroscopy (PM IRRAS) was successfully used for the first time to characterize an optically transparent thin oxide film. SiO2 layers of 7 nm thickness were synthesized by plasma enhanced chemical vapor deposition (PECVD) on 200 nm thick gold covered glass slides. Despite the fact that silica is transparent and absorptive to IR radiation when deposited in the form of thin films on a gold surface, it preserves the high metallic reflectivity for the IR light. At grazing angles of incidence of the IR beam, the enhancement of the normal component of the electric field at the interface is comparable to that of Au alone. In addition, the analysis of the structure of a 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) lipid monolayer deposited using the Langmuir-Blodgett technique is demonstrated.
Occurrence of a resistance breaking pathotype of Meloidogyne javanica on tomatoes in Crete, Greece (1996)

The root galling and reproduction of live single egg mass lines of Meloidogyne javanica originating from three different field sites of Crete was assessed on fourteen resistant tomato hybrid cultivars (Scala, 7352 Silco, Myno, Menglo, Rakata, GC785, GC788 Alpado, Bermuda, 7353, 7358, W1964, W1967, W2913, 399) in a controlled environment where soil temperature was 22-24 oc. Two !ines originating from a field where the resistant cv. Menglo had been grown for two years were able to infect the resistant cultivars and to reproduce on them as weil as on a susceptible cultivar (Carouso). One line isolated from cucumber infected and reproduced only on the susceptible cultivars. Two lines from a field where the susceptible cultivar Carouso was grown showed either slight or no reproduction on resistant cultivars. Under greenhouse conditions (soil temperature 20-42 OC) Mi conferred resistance was nullified and ail cultivars became hosts for an aviruJent line.
PrivacyGuard: Enforcing Private Data Usage Control with Blockchain and Attested Off-chain Contract Execution (2019)

The abundance and rich varieties of data are enabling many transformative applications of big data analytics that have profound societal impacts. However, there are also increasing concerns regarding the improper use of individual data owner's private data. In this paper, we propose PrivacyGuard, a system that leverages blockchain smart contract and trusted execution environment (TEE) to enable individual's control over the access and usage of their private data. Smart contracts are used to specify data usage policy, i.e., who can use what data under which conditions and what analytics to perform, while the distributed blockchain ledger is used to keep an irreversible and non-repudiable data usage record. To address the efficiency problem of on-chain contract execution and to prevent exposing private data on the publicly viewable blockchain, PrivacyGuard incorporates a novel TEE-based off-chain contract execution engine along with a protocol to securely commit the execution result onto blockchain. We have built and deployed a prototype of PrivacyGuard with Ethereum and Intel SGX. Our experiment result demonstrates that PrivacyGuard fulfills the promised privacy goal and supports analytics on data from a considerable number of data owners.
5-W Yellow Laser by Intracavity Frequency Doubling of High-Power Vertical-External-Cavity Surface-Emitting Laser (2008)

We report on the development of a high-power tunable yellow-orange laser. It is based on intracavity frequency doubling of a widely tunable, highly strained InGaAs-GaAs vertical-external-cavity surface-emitting laser operating near 1175 nm. Over 5 W of continuous-wave output power is achieved and is tunable over a 15-nm band centered at 587 nm. This compact low-cost high-power yellow-orange laser provides an innovative alternative for sodium guidestar lasers, medical and communication applications.
The average distances in random graphs with given expected degrees (2002)

Random graph theory is used to examine the "small-world phenomenon"; any two strangers are connected through a short chain of mutual acquaintances. We will show that for certain families of random graphs with given expected degrees the average distance is almost surely of order log nlog d, where d is the weighted average of the sum of squares of the expected degrees. Of particular interest are power law random graphs in which the number of vertices of degree k is proportional to 1kbeta for some fixed exponent beta. For the case of beta > 3, we prove that the average distance of the power law graphs is almost surely of order log nlog d. However, many Internet, social, and citation networks are power law graphs with exponents in the range 2 < beta < 3 for which the power law random graphs have average distance almost surely of order log log n, but have diameter of order log n (provided having some mild constraints for the average distance and maximum degree). In particular, these graphs contain a dense subgraph, which we call the core, having n(clog log n) vertices. Almost all vertices are within distance log log n of the core although there are vertices at distance log n from the core.
Characterization of a bovine cone photoreceptor phosphodiesterase purified by cyclic GMP-sepharose chromatography. (1988)

The biochemical bases for the differences in cone and rod photoreceptor physiology have not been thoroughly examined because of the difficulty in obtaining cone photoreceptor components. We report here the purification and preliminary characterization of a bovine cyclic GMP phosphodiesterase (PDE) which is enriched in cone photoreceptors. The cone PDE was purified at least 15,000-fold to apparent homogeneity from bovine retinas by DEAE-cellulose and cGMP-Sepharose affinity chromatography. The trypsin-activated cone PDE hydrolyzed cGMP with efficiency similar to that of the rod PDE. However, a number of characteristics distinguished the cone PDE from the rod isozyme including the subunit structure. As previously reported, the apparent molecular weight of the cone PDE large subunit (alpha') was slightly larger than either of the large subunits of the rod PDE (93,500 versus 88,000 and 84,000). Three other smaller polypeptides were associated with the alpha' subunit (Mr = 11,000, 13,000, and 15,000), one of which (11,000) may be identical to the rod PDE gamma subunit. Cone phosphodiesterase binds at least 10-fold more cyclic GMP/mol of PDE than the rod photoreceptor isozyme. Cyclic GMP binds to this noncatalytic site with high affinity (Kd = 11 nM) and dissociates very slowly (t1/2 = 10-20 min at 37 degrees C). Purified rod transducin activated the cone PDE in solution to at least 90% of the trypsin-activated level. The concentration of rod transducin required for half-maximal activation of cone PDE (15 nM) was 50-fold lower than that necessary for half-maximal activation of rod PDE. Thus several properties of the cone phosphodiesterase clearly distinguish it from the rod isozyme and could account for some differences in cone and rod physiology.
Physical Activity after Diagnosis and Risk of Prostate Cancer Progression: Data from the Cancer of the Prostate Strategic Urologic Research Endeavor (2011)

Vigorous activity after diagnosis was recently reported to be inversely associated with prostate cancer-specific mortality. However, men with metastatic disease may decrease their activity due to their disease; thus, a causal interpretation is uncertain. We therefore prospectively examined vigorous activity and brisk walking after diagnosis in relation to risk of prostate cancer progression, an outcome less susceptible to reverse causation, among 1,455 men diagnosed with clinically localized prostate cancer. Cox proportional hazards regression was used to examine vigorous activity, nonvigorous activity, walking duration, and walking pace after diagnosis and risk of prostate cancer progression. We observed 117 events (45 biochemical recurrences, 66 secondary treatments, 3 bone metastases, 3 prostate cancer deaths) during 2,750 person-years. Walking accounted for nearly half of all activity. Men who walked briskly for 3 h/wk or more had a 57% lower rate of progression than men who walked at an easy pace for less than 3 h/wk (HR = 0.43; 95% CI: 0.21-0.91; P = 0.03). Walking pace was associated with decreased risk of progression independent of duration (HR brisk vs. easy pace = 0.52; 95% CI: 0.29-0.91; P(trend) = 0.01). Few men engaged in vigorous activity, but there was a suggestive inverse association (HR ≥3 h/wk vs. none = 0.63; 95% CI: 0.32-1.23; P(trend) = 0.17). Walking duration and total nonvigorous activity were not associated with risk of progression independent of pace or vigorous activity, respectively. Brisk walking after diagnosis may inhibit or delay prostate cancer progression among men diagnosed with clinically localized prostate cancer.