gebhart/patrepeval huggingface dataset:
Online cross-calibration of camera and LIDAR (2017)

In an autonomous driving system, drift can affect the sensor's position, introducing errors in the extrinsic calibration. For this reason, we have developed a method which continuously monitors two sensors, camera, and LIDAR with 16 beams, and adjusts the value of their cross-calibration. Our algorithm, starting from correct values of the extrinsic cross-calibration parameters, can detect small sensor drift during vehicle driving, by overlapping the edges from the LIDAR over the edges from the image. The novelty of our method is that in order to obtain edges, we create a range image and filter the data from the 3D point cloud, and we use distance transform on 2D images to find edges. Another improvement we bring is applying motion correction on laser scanner data to remove distortions that appear during vehicle motion. An optimization problem on the 6 calibration parameters is defined, from which we are able to obtain the best value of the cross-calibration, and readjust it automatically. Our system performs successfully in real time, in a wide variety of scenarios, and is not affected by the speed of the car.
Frequency analysis of seismic waves (1952)

Abstract This paper contains a brief description of the general factors governing choice of recording media; a description of the instrumentation employed in wave analysis studies; a review of some of the factors involved in the generation of seismic waves and their propagation; and a few examples of wave separation to illustrate some of the points discussed and their application to seismic exploration. The results of these studies demonstrate that instrumentation of this type is of advantage in those areas where frequency discrimination can improve the signal/interference ratio.
GCR1 of Saccharomyces cerevisiae encodes a DNA binding protein whose binding is abolished by mutations in the CTTCC sequence motif. (1991)

In Saccharomyces cerevisiae, glycolysis enzymes constitute 30-60% of the soluble protein. GCR1 gene function is required for high-level glycolytic gene expression. In gcr1 mutant strains the levels of most glycolytic enzymes are between 2% and 10% of wild type. Binding sites for the global regulatory protein known as repressor activator protein 1 (RAP1)/general regulatory factor 1 (GRF1)/translation upstream factor (TUF) are found in close proximity to one or more CTTCC sequence motifs in the controlling region of GCR1-dependent genes. RAP1/GRF1/TUF-binding sites are known to be essential elements of upstream activating sequences that control expression of many glycolytic genes. In this report, I demonstrate that GCR1 encodes a DNA binding protein whose ability to bind DNA is dependent on the CTTCC sequence motif. This finding, in addition to the work of others, suggests that the GCR1 gene product and the RAP1/GRF1/TUF gene product act in concert to mediate high-level glycolytic gene expression.
Effect of Chemical Interactions in Pentachlorophenol Mixtures on Skin and Membrane Transport (2002)

Pentachlorophenol (PCP) has been widely used as a pesticide, and topical exposure to a chemical mixture can alter its dermal absorption. The purpose of this study was to evaluate the influence of single and binary solvent systems (ethanol, EtOH, and water), a surfactant (6% sodium lauryl sulfate, SLS), and a rubifacient/vasodilator (1.28% methyl nicotinate, MNA) on PCP membrane transport, and to correlate these effects with physiochemical characteristics of the PCP mixtures. Partitioning, diffusion, and absorption parameters of (14)C-PCP at low (4 microg/cm(2)) and high (40 microg/cm(2)) doses were assessed in porcine skin and silastic membranes in vitro. In these 8-h, flow-through diffusion studies, PCP was dosed with the following vehicles: 100% EtOH, 100% water, 40% EtOH + 60% water, 40% EtOH + 60% water + SLS, 40% EtOH + 60% water + MNA, and 40% EtOH + 60% water + SLS + MNA. PCP absorption ranged from 1.55-15.62% for the high dose and 0.43-7.20% for the low dose. PCP absorption, flux, and apparent permeability were influenced by PCP solubility, and PCP apparent permeability was correlated with log PC (r2 = 0.66). Although PCP was very soluble in pure ethanol (100%), this vehicle evaporated very rapidly, and PCP absorption in ethanol was the lowest with this vehicle when compared to pure water (100%) or aqueous ethanol mixtures in general. MNA had no significant effect on membrane absorption or relative permeability R(P) in aqueous ethanol solutions, but the presence of the surfactant, SLS, significantly reduced PCP absorption and R(P) in both membrane systems. In conclusion, these studies demonstrated that modification in mixture composition with either a solvent and/or a surfactant can influence PCP diffusion in skin. Physicochemical interactions between these mixture components on the skin surface and stratum corneum contributed significantly to PCP transport, and these interactions were identified by simultaneously assessing chemical diffusion in biological and inert membrane systems.
Laboratory study of breast cancer using conventional and molecular cytogenetics. (1996)

Currently, the factors associated with tumor initiation, progression, invasion and metastasis as well as the complex relationship between the genetics of breast cancer are not clearly understood. It is known, however, that the risk of developing breast cancer increases with age, family history of breast cancer, and not bearing a child by age 30. Most breast cancer cases (i.e., greater than 70 percent), however, occur in women who have no identifiable risk factors. The basic methods of treatment (e.g., surgery, chemotherapy and radiation) used today are the same as those used in the 1930s. The current criteria for breast cancer staging include pathologic parameters, such as tumor size and nodal involvement, histologic and cytologic parameters, such as histologic grade, and biologic parameters such as age of the patient, hormone (estrogen and progesterone) receptor status, oncogene activation (e.g., c-myc and HER-2/neu) and tumor suppressor gene inactivation (e.g., p53). Although there is evidence that some of these factors may offer some utility in prognosis, the optimal combination of independent prognostic factors remains elusive. Thus, the need to explore other potential biomarkers is pressing. Laboratory study of breast cancer using conventional and molecular cytogenetics, together with other forms of analysis, will lead to an improved repertoire of biological markers in the future.
Treatment of Ureteral Stones by Ureteroscopy (1987)

No AccessJournal of Urology1 Jun 1987Treatment of Ureteral Stones by Ureteroscopy Jobst Pastor, Jürgen Graff, Peter Mach, Lothar Hertle, Peter-J. Funke, Claus Fischer, Wolfgang Diederichs, and Theodor Senge Jobst PastorJobst Pastor More articles by this author , Jürgen GraffJürgen Graff More articles by this author , Peter MachPeter Mach More articles by this author , Lothar HertleLothar Hertle More articles by this author , Peter-J. FunkePeter-J. Funke More articles by this author , Claus FischerClaus Fischer More articles by this author , Wolfgang DiederichsWolfgang Diederichs More articles by this author , and Theodor SengeTheodor Senge More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)75917-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Treatment of Ureteral Stones by Ureteroscopy." The Journal of Urology, 137(6), p. 295A © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 137Issue 6June 1987Page: 295A Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Jobst Pastor More articles by this author Jürgen Graff More articles by this author Peter Mach More articles by this author Lothar Hertle More articles by this author Peter-J. Funke More articles by this author Claus Fischer More articles by this author Wolfgang Diederichs More articles by this author Theodor Senge More articles by this author Expand All Advertisement PDF downloadLoading ...
New Well Design in the Statfjord Field Utilizing a Multi-lateral Well in Low Productive Zones in the Brent Reservoir (1998)

Abstract The value of multi-lateral well technology is increasing for the Statfjord field. This first cased multi-lateral well was drilled from the last vacant slot on the three Statfjord platforms. At the same time, limiting the production decline is increasingly dependent on successful drainage of remaining oil pockets by infill drilling. This paper presents a case history covering the drilling and completion of the multi-lateral well C-23 on the Statfjord field. The well was drilled with two horizontal branches in the Brent reservoir, 1765 m and 2394 m long respectively. The two horizontal wellbores both penetrate the Talbert and the Ness formation in the same direction, with a distance between each branch of only 80 m. Both laterals have 7" cemented liners in the reservoir. The lateral has been perforated in the Tarbert formation using a snubbing unit. The following list outlines the main issues that will be described in the paper:–The commercial and technical justification for drilling a multi-lateral well on the Statfjord field and the technical requirements in each lateral.–Key issues in the planning phase.–The importance of establishing a dedicated team together with the service companies covering all disciplines.–The drilling phase, focusing on general well design, well profile, drilling technology (including the use of a rotary steerable system), runing and cementing of 9 5/8" and 7" liners, as well as time schedule.–Design and requirements for the junction at 2376 mMD. Special emphasis will be put on the most critical phases, including the solid whipstock exchange and re-establishing communication to the main bore.–Running and cementing the 2421 m long 7" liner in the lateral, and the use of a proprietary tough cement.–Completion design and production strategy. P. 547
Enzymatic regeneration of ATP. I. Alternative routes (1976)

Abstract Prospects for enzymatic synthesis processes on an industrial scale depend upon development of a practical process for ATP regeneration. The relative merits of various routes to ATP regeneration involving chemical synthesis, whole cells or organelles, or cell free enzymes are evaluated. The most promising route involves one or more enzyme incorporating the reaction catalyzed by acetate kinase for ADP phosphorylation.
The Correlation of Protective Effects and Antibody Production in Immunized Chickens with Recombinant R7 Vaccine against Leucocytozoon caulleryi. (2002)

Protective effects of recombinant R7 (rR7) vaccine against Leucocytozoon caulleryi in chickens were studied. After injection of oil-adjuvanted rR7 vaccine into chickens, antibody titers against second-generation schizonts (2GS) antigen of L. caulleryi (anti-2GS antibody) rapidly rose in all the immunized chickens, reached to a peak value 2 weeks after injection, and the titers persisted through 4 or 5 months after injection. Chickens having high levels of the anti-2GS antibody titers (> or = 102,400 ) at pre-challenge completely protected against sporozoites challenge of L. caulleryi. After the challenge inoculation, relatively high parasitemia of L. caulleryi was observed in all the inadequately immunized chickens having low levels of the antibody titers (< or = 3,200) at pre-challenge, although some of them seemed to be clinically normal. Correlation of protective effects in the immunized chickens was observed between both prevention of appearance of clinical signs and parasitemia after parasites challenge and anti-2GS antibody titers of the chickens at pre-challenge. The present study shows that chicken leucocytozoonosis can be prevented by vaccination, and humoral immunity may play an important role in the control of chicken leucocytozoonosis.
Formula Student 2012 (2012)

Los integrantes del equipo de la UPCT conducirán el prototipo que ellos mismos han fabricado. La diferencia de estos jóvenes con un piloto profesional de Formula 1 está en que conocen al detalle la composición de cada elemento de su vehículo, porque ellos son los que han diseñado este monoplaza de carreras. En esta edición de la competición Formula Student, los alumnos estuvieron acompañados por Miguel Lucas, profesor asociado que forma parte de los tutores que participan en el proyecto Formula Student UPCT, y el coordinador de este proyecto.\nLos jueces que evalúan el trabajo de los alumnos proceden de grandes compañías como Land Rover, Nissan, Airbus, Ford, National Instruments, de la SAE, de la IMechE y de importantes universidades, y en la mayor parte de los casos consisten en jefes de producción, jefes de producto e ingenieros con dilatada experiencia en innovación tecnológica y desarrollo de producto. Patricio Franco destaca que “en esta competición los alumnos cubren la totalidad de las fases del lanzamiento de un nuevo producto al mercado, que además en este caso consiste en un producto de especial complejidad como es un monoplaza de competición, incluyendo su diseño detallado, análisis computacional, ensayo, optimización, fabricación, montaje y puesta a punto, además de la conducción de su propio prototipo y la defensa del diseño desarrollado, la planificación de la producción y los planes de ventas para la supuesta fabricación en serie y comercialización del vehículo diseñado, lo cual permite cubrir la totalidad de las tareas teóricas y prácticas que están detrás de la concepción de un nuevo producto y es por tanto una experiencia extraordinaria para la formación de nuestros alumnos”. \nUPCT Racing Team, lograron el segundo puesto entre las universidades españolas participantes en Formula Student, la competición de mayor prestigio a nivel mundial en el ámbito de la Ingeniería. Los 25 estudiantes de la UPCT han que-dado en el puesto número 28 entre las más de 120 universidades participantes. La competición se ha celebrado reciente-mente en el Circuito de Silverstone (Reino Unido). Los participantes han conseguido posicionar a la UPCT entre las principales instituciones universitarias del mundo en cuanto al desarrollo de vehículos para la alta competición. La UPCT se ha clasificado por delante de muchas de las universidades de mayor prestigio de esta competición y en las pruebas de fabricación del monoplaza y lanzamiento de producto ha quedado por delante de la ETH Zurich, Delft University of Technology, University of Cambridge, TU Graz y TU Munich.
Purification, characterization and gene cloning of 6‐hydroxynicotinate  3‐monooxygenase from <i>Pseudomonas fluorescens</i> TN5 (1999)

6-Hydroxynicotinate 3-monooxygenase, a membrane-bound, 42-kDa monomeric enzyme from Pseudomonas fluorescens TN5 was purified and characterized. The enzyme catalyzes the oxidative decarboxylation of 6-hydroxynicotinate and depends on O2, NADH and FAD with the holoenzyme containing 1 M of FAD per 1 M of enzyme. The isolated enzyme was used for the synthesis of 2,5-dihydroxypyridine, a precursor for the chemical synthesis of 5-aminolevulinic acid, which is applied as a plant growth hormone, a herbicide and in cancer therapy. A 1.8-kbp DNA fragment, which contains the ORF encoding 6-hydroxynicotinic acid 3-monooxygenase, was cloned, sequenced and expressed in Escherichia coli. The deduced 385 amino acid sequence of the cloned ORF is in agreement with the enzyme molecular mass, amino acid sequence of an internal peptide, contains a putative FAD-binding site and is homologous to similar flavoproteins such as salicylate 1-monoxygenase.
Constituents of Essential Oils from<i>Nepeta cataria</i>L.,<i>N. grandiflora</i>M.B. and<i>N. nuda</i>L. (1996)

ABSTRACT Essential oils from Bulgarian populations of Nepeta nuda L. and N. cataria L. (two origins) and of the Caucasian endemic N. grandiflora M.B. (Lamiaceae) were analyzed by GC/MS, TLC and chemical transformation. Iridoids of the nepetalactone type were the main constituents, accompanied by other terpenoids. Some of the constituents were found for the first time in the genus Nepeta from natural sources.
ChemInform Abstract: Synthesis of Enantioenriched γ‐Quaternary Cycloheptenones Using a Combined Allylic Alkylation/Stork—Danheiser Approach: Preparation of Mono‐, Bi‐, and Tricyclic Systems. (2012)

Abstract The addition of Grignard or organolithium compounds to enantioenriched vinylogous ester (I) followed by finely tuned quenching conditions affords β‐functionalized cycloheptenones.
Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy (2016)

Alternative splicing is a regulated process that results in expression of specific mRNA and protein isoforms. Alternative splicing factors determine the relative abundance of each isoform. Here we focus on MBNL1, a splicing factor misregulated in the disease myotonic dystrophy. By altering the concentration of MBNL1 in cells across a broad dynamic range, we show that different splicing events require different amounts of MBNL1 for half-maximal response, and respond more or less steeply to MBNL1. Motifs around MBNL1 exon 5 were studied to assess how cis-elements mediate the MBNL1 dose-dependent splicing response. A framework was developed to estimate MBNL concentration using splicing responses alone, validated in the cell-based model, and applied to myotonic dystrophy patient muscle. Using this framework, we evaluated the ability of individual and combinations of splicing events to predict functional MBNL concentration in human biopsies, as well as their performance as biomarkers to assay mild, moderate, and severe cases of DM.
Distance Oracles for Sparse Graphs (2009)

Thorup and Zwick, in their seminal work, introduced the approximate distance oracle, which is a data structure that answers distance queries in a graph. For any integer k, they showed an efficient algorithm to construct an approximate distance oracle using space O(kn <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1+1/k</sup> ) that can answer queries in time O(k) with a distance estimate that is at most ¿ = 2k-1 times larger than the actual shortest distance (this ratio is called the stretch).They proved that, under a combinatorial conjecture, their data structure is optimal in terms of space: if a stretch of at most 2k-1 is desired, then the space complexity is at least n <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1+1/k</sup> . Their proof holds even if infinite query time is allowed: it is essentially an "incompressibility" result. Also, the proof only holds for dense graphs, and the best bound it can prove only implies that the size of the data structure is lower bounded by the number of edges of the graph. Naturally, the following question arises: what happens for sparse graphs? In this paper we give a new lower bound for approximate distance oracles in the cell-probe model. This lower bound holds even for sparse (polylog(n)-degree) graphs, and it is not an "incompressibility" bound: we prove a three-way tradeoff between space, stretch, and query time. We show that when the query time is t and the stretch is ¿, then the space S must be S ¿ n <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1+¿(1/t¿)</sup> /lg n. This lower bound follows by a reduction from lopsided set disjointness to distance oracles, based on and motivated by recent work of Patrascu. Our results in fact show that for any high-girth regular graph, an approximate distance oracle that supports efficient queries for all subgraphs of G must obey this tradeoff. We also prove some lemmas that count sets of paths in high-girth regular graphs and high-girth regular expanders, which might be of independent interest.
Efficacy of nano-hydroxyapatite prepared by an aqueous solution combustion technique in healing bone defects of goat (2008)

The present study was undertaken to evaluate porous hydroxyapatite (HAp), the powder of which was prepared by a novel aqueous solution combustion technique, as a bone substitute in healing bone defects in vivo, as assessed by radiologic and histopathologic methods, oxytetracycline labeling, and angiogenic features in Bengal goat. Bone defects were created in the diaphysis of the radius and either not filled (group I) or filled with a HAp strut (group II). The radiologic study in group II showed the presence of unabsorbed implants which acted as a scaffold for new bone growth across the defect, and the quality of healing of the bone defect was almost indistinguishable from the control group, in which the defect was more or less similar, although the newly formed bony tissue was more organized when HAp was used. Histologic methods showed complete normal ossification with development of Haversian canals and well-defined osteoblasts at the periphery in group II, whereas the control group had moderate fibro-collagenization and an adequate amount of marrow material, fat cells, and blood vessels. An oxytetracycline labeling study showed moderate activity of new bone formation with crossing-over of new bone trabeculae along with the presence of resorption cavities in group II, whereas in the control group, the process of new bone formation was active from both ends and the defect site appeared as a homogenous non-fluoroscent area. Angiograms of the animals in the control group showed uniform angiogenesis in the defect site with establishment of trans-transplant angiogenesis, whereas in group II there was complete trans-transplant shunting of blood vessel communication. Porous HAp ceramic prepared by an aqueous combustion technique promoted bone formation over the defect, confirming their biologic osteoconductive property.
Carbamylation of Amino and Tyrosine Hydroxyl Groups (1967)

The reactions of cyanate with model compounds containing amino and tyrosine hydroxyl groups have been studied in detail.The reactions involve nucleophilic addition of the amino or phenoxide group to the molecular form of cyanic acid.The proposed mechanism of the reactions has aided in the selection of optimal experimental conditions for the carbamylation of amino and tyrosine hydroxyl groups in proteins and peptides.Carbamylation represents a useful reaction for the reversible blocking of tyrosine hydroxyl groups, the 0-carbamyl substituent being readily removed by hydrolysis at neutral and alkaline pH values.By application of the cyanate reaction to oxytocin, two new analogues were obtained, IV-carbamyl-0-carbamyloxytocin and N-carbamyloxytociu.The sites of reaction and degree of purity were determined by experiments involving degradation of the molecules and by the use of radioactive labeling.On the isolated uterus, IV-carbamyl-0-carbamyloxytocin acts as an inhibitor of oxytocin without itself possessing oxytocic activity; Wcarbamyloxytocin is a feebly active analogue with no inhibitory properties.At pH 7.4 and 37', the inhibitory analogue undergoes slow hydrolysis to yield the weakly active analogue.The very low activity of IV-carbamyloxytocin provides an explanation for the inactivation of oxytocin by 8 M urea.'CH,-!H-NH-AspNH, -GIuNH, c=o