gebhart/patrepeval huggingface dataset:
Relationship between Nutritional Status and Immune Function of Elderly People (1994)

Thirty-four malnourished subjects between the ages of 61 and 97 years were given appropriate food supplement(s) for a period of 6 consecutive months. They were followed for a subsequent 6 months during which time there was no nutritional intervention. Nutritional assessment and immunological evaluation were performed at 0, 6, and 12 months. Nutritional assessment included anthropometry, biochemistry, and clinical examination. Immunological evaluation included serum complement C3 concentration, delayed cutaneous hypersensitivity skin test, and the enumeration of total lymphocytes, rosetting T-cells, CD4+ cells, and CD8+ cells. Immune function improved by the end of the supplementation period. Six months of nutritional supplementation significantly increased the percentage of lymphocytes represented by mature T-cells.
Identification of novel integrin binding partners for CIB1: structural and thermodynamic basis of CIB1 promiscuity (2020)

The short cytoplasmic tails of the α and β chains of integrin adhesion receptors regulate integrin activation and cell signaling. Significantly less is known about proteins that bind to α-integrin cytoplasmic tails (CTs) than β-CTs to regulate integrins. CIB1 was previously identified as an αIIb binding partner that inhibits agonist-induced activation of the platelet-specific integrin, αIIbβ3. A sequence alignment of all α-integrin CTs revealed that key residues in the CIB1 binding site on αIIb are well-conserved, and was used to delineate a consensus binding site (I/L-x-x-x-L/M-W/Y-K-x-G-F-F). Because the CIB1 binding site on αIIb is conserved in all α-integrins, and CIB1 expression is ubiquitous, we asked if CIB1 could interact with other α-integrin CTs. We predicted that multiple α-integrin CTs were capable of binding to the same hydrophobic binding pocket on CIB1 with docking models generated by all-atom replica exchange discrete molecular dynamics. After demonstrating novel in vivo interactions between CIB1 and other whole integrin complexes with co-immunopreceipitations, we validated the modeled predictions with solid-phase competitive binding assays showing that other α-integrin CTs compete with the αIIb CT for binding to CIB1 in vitro. Isothermal titration calorimetry measurements indicated that this binding is driven by hydrophobic interactions and depends on residues in the CIB1 consensus binding site. These new mechanistic details of CIB1-integrin binding imply that CIB1 could bind to all integrin complexes and act as a broad regulator of integrin function.
Insertion Sequence IS <i>Aba11</i> Is Involved in Colistin Resistance and Loss of Lipopolysaccharide in Acinetobacter baumannii (2011)

Infections caused by Acinetobacter baumannii are of increasing concern, largely due to the multidrug resistance of many strains. Here we show that insertion sequence ISAba11 movement can result in inactivation of the A. baumannii lipid A biosynthesis genes lpxA and lpxC, resulting in the complete loss of lipopolysaccharide production and high-level colistin resistance.
Forgery Detection and Value Identification of Euro Banknotes (2013)

This paper describes both hardware and software components to detect counterfeits of Euro banknotes. The proposed system is also able to recognize the banknote values. Differently than other state-of-the-art methods, the proposed approach makes use of banknote images acquired with a near infrared camera to perform recognition and authentication. This allows one to build a system that can effectively deal with real forgeries, which are usually not detectable with visible light. The hardware does not use any mechanical parts, so the overall system is low-cost. The proposed solution is reliable for ambient light and banknote positioning. Users should simply lean the banknote to be analyzed on a flat glass, and the system detects forgery, as well as recognizes the banknote value. The effectiveness of the proposed solution has been properly tested on a dataset composed by genuine and fake Euro banknotes provided by Italy's central bank.
The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go. (1987)

The structures of the guanosine 5'O-(3-thio)triphosphate (GTP gamma S)-containing guanine nucleotide-binding regulatory proteins (G proteins) are distinct from those of the GDP-containing forms. One indication of the conformational change caused by GTP gamma S is a Mg2+-sensitive increase in the intensity of the proteins' tryptophan fluorescence (Higashijima, T., Ferguson, K.M., Sternweis, P.C., Ross, E.M., Smigel, M.D., Gilman, A.G. (1987), J. Biol. Chem., 262, 762-766). GTP causes a similar change in the fluorescence of Go, a G protein from bovine brain. When Mg2+ is also present, the increase in fluorescence is transient, and the rate of decline in the intensity of the fluorescence is the same as the rate of GTP hydrolysis by the protein. The steady-state rate of hydrolysis of GTP by Go (0.3-0.4/min) is slower than the catalytic rate of the protein (2/min), because the rate-limiting step in the reaction is the release of GDP.
Data extraction from web pages based on structural-semantic entropy (2012)

Most of today's web content is designed for human consumption, which makes it difficult for software tools to access them readily. Even web content that is automatically generated from back-end databases is usually presented without the original structural information. In this paper, we present an automated information extraction algorithm that can extract the relevant attribute-value pairs from product descriptions across different sites. A notion, called structural-semantic entropy, is used to locate the data of interest on web pages, which measures the density of occurrence of relevant information on the DOM tree representation of web pages. Our approach is less labor-intensive and insensitive to changes in web-page format. Experimental results on a large number of real-life web page collections are encouraging and confirm the feasibility of the approach, which has been successfully applied to detect false drug advertisements on the web due to its capacity in associating the attributes of records with their respective values.
Room Temperature Preparation of Trifluoroethenylzinc Reagent by Metalation of the Readily Available Halocarbon HFC‐134a and an Efficient, Economically Viable Synthesis of 1,2,2‐Trifluorostyrenes. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Privatisation and the RDP: A Critical Assessment (2025)

Recent proposals, particularly those emanating from Thabo Mbeki, to privatise state corporations in order to finance the Reconstruction and Development Programme (RDP), present a stark reminder of just how far ANC economic thinking appears to have shifted over the last few years.1 Under an unprecedented ideological assault from big business and the media, initial commitments to public ownership, as derived from the Freedom Charter, first gave way to a compromise around 'the mixed economy' and 'growth through redistribution'. These terms now seem to belong to the distant past with the RDP being diminished both in its content and in the means to implement it. It scarcely seems credible that a privatisation programme, which was substantially brought to a halt by popular and organised resistance in the late- 1980s, should now be warmly and so quickly embraced by the Government of National Unity. The purpose here is four-fold. First, the general arguments for and against privatisation are briefly assessed in order to show how limited is the case for privatisation in terms of both the content and the scope of the factors brought into consideration. Second, the privatisation programme of the previous government is assessed in order to identify the underlying economic and political factors involved. This is done, third, in order to see how these factors have changed so that government may once again put forward privatisation proposals - only now with greater confidence of success. Finally, the likely impact of a privatisation programme is assessed against its supposed goals of financing and furthering a progressive social and economic reconstruction. Those less interested in the theory and the past may simply jump to this last substantive section, which is intended to stand alone even if at the expense of a little repetition from the earlier sections.
Methylation of elongation factor 1 alpha from the fungus Mucor. (1982)

A basic protein from the dimorphic fungus Mucor racemosus, found to be highly methylated, is shown to be protein synthesis elongation factor 1 alpha. This protein is the most abundant protein in hyphal cells but is less abundant in yeast cells. It is post-translationally methylated with the formation of mono-, di-, and trimethyllysine at as many as 16 sites. Nearly 20% of the 44 lysine residues of elongation factor 1 alpha from mycelia are modified while those from sporangiospores are virtually unmethylated.
Diethylstilboestrol: the binding and effects of diethylstilboestrol upon the polymerisation and depolymerisation of purified microtubule protein <i>in vitro</i> (1985)

Diethylstilboestrol (DES) was shown to bind to purified microtubule (MT) protein and inhibit the binding of colchicine. The polymerisation and depolymerisation characteristics of MT protein in vitro were examined using spectrophotometry and electron microscopy. At high doses of DES the polymerisation of intact microtubules was inhibited, whilst at lower doses enhanced microtubule formation was observed. The lower doses of DES inhibit the depolymerisation of intact microtubules.
Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells. (1994)

Prostacyclin synthase catalyzes the conversion of prostaglandin H2 to prostacyclin, which is a powerful vasodilator and the most potent natural occurring inhibitor of platelet aggregation. In the present study, we determined the amino acid sequence of bovine prostacyclin synthase by combined protein chemical and molecular cloning techniques. The enzyme was purified and characterized from bovine aorta microsomes, and the partial amino acid sequences were determined with the native enzyme and endoproteinase Lys-C-cleaved peptides. Using primers synthesized according to the amino acid sequences, cDNA coding for prostacyclin synthase was amplified by polymerase chain reaction with bovine endothelial cell poly(A)+ RNA and cloned into pBluescript II. Nucleotide sequence analyses of the cloned cDNA inserts revealed that cDNA for this enzyme contained a 1500-base pair open reading frame coding for a 500-amino acid polypeptide with a M(r) of 56,628. COS-7 cells transfected with an expression plasmid harboring this cDNA clone expressed prostacyclin synthase activity. The primary structure of the enzyme showed structural characteristics of cytochrome P450 and exhibited a 32% identity to that of human cholesterol 7 alpha-hydroxylase. However, the identity between the amino acid sequences of bovine prostacyclin synthase and human thromboxane synthase was only 16%, and no P450 showed an identity higher than 40%, suggesting that prostacyclin synthase represents a new family in the P450 superfamily. RNA blot analysis indicated that the mRNA for prostacyclin synthase from bovine endothelial cells showed a size of approximately 2.7 kilobases and that the mRNA level increased about 3-fold by treatment of tumor necrosis factor-alpha.
Northerners at War: Reflections on the Civil War Home Front. By J. Matthew Gallman (2011)

J. Matthew Gallman’s new collection of essays, Northerners at War , is as much a work of academic autobiography as it is of historical scholarship. Gallman has brought together a collection of eleven previously published essays that, over the years, have not only contributed to our understanding of the Northern home front during the Civil War, but also map out the academic journey and various intellectual pursuits of one of the leading scholars of Pennsylvania’s Civil War experience.
[Severe hypotension as a complication of intramyometrial injection of vasopressin: a case report]. (2008)

A thirty-year-old woman was scheduled for laparoscopic myomectomy. After insertion of an epidural catheter at the L4-5 interspace, general anesthesia was induced with thiopental 250 mg followed by vecuronium 8mg intravenously to facilitate tracheal intubation. General anesthesia was maintained with sevoflurane and nitrous oxide. Just after intramyometrial injection of vasopressin, blood pressure decreased from 122/66 to 45/25 mmHg, and heart rate decreased from 52 to 45 beats x min(-1). The patient was ventilated with 100% oxygen, and we administered atropine 0.25 mg and ephedrine 16 mg intravenously. Blood pressure increased to 150/100 mmHg and heart rate increased to 135 beats x min(-1). Since electrocardiogram showed ST-segment depression and premature ventricular contraction, we administered nicorandil 3 mg followed by continuous infusion at a rate of 3 mg x hr(-1), and lidocaine 60 mg, intravenously. The ST depression and premature ventricular contraction disappeared immediately. To decrease blood pressure and heart rate, we increased inspiratory concentrations of sevoflurane and nitrous oxide and administered local anesthetics via epidural catheter, and hemodynamic parameters became gradually stable. We estimate that severe hypotension observed in this case is associated with intramyometrial injection of vasopressin. Increased blood concentration of vasopressin might cause vasoconstriction of coronary artery, increases in afterload, and/or direct myocardial depression resulting in decreased cardiac output.
Michaël Graetz, Les Juifs en France au XIXe siècle : de la Révolution française à l'Alliance Israélite universelle (1990)

Green Nancy L. Michaël Graetz, Les Juifs en France au XIXe siècle : de la Révolution française à l'Alliance Israélite universelle. In: Annales. Économies, Sociétés, Civilisations. 45ᵉ année, N. 3, 1990. pp. 678-679.
Observation of very large chiral domains in a liquid crystal phase formed by mixtures of achiral bent-core and rod molecules (2005)

Experimental observations on the B4 phase of liquid crystal mixtures formed from bent-core (P-8-O-PIMB) and rod (5CB) achiral molecules reveal the stabilization of the B4 phase with an unusually large size of chiral domains. The phenomenon is interpreted as an intrinsic property of the B4 phase when arising below the isotropic liquid (Iso); actually direct transition between Iso and B4 phases occurs except for only very limited regions of pure P-8-O-PIMB and 5CB molecules. The phase diagram of the mixture shows the existence of a new phase, closely related to the B4 phase.
Minoxidil-Induced Changes in the Contraction of Collagen Lattices by Human Skin Fibroblasts (1992)

This investigation has studied the effect of minoxidil on the contraction of hydrated collagen lattices by human dermal fibroblasts. Type I collagen was mixed with a fibroblast suspension and polymerized, and minoxidil 10 to 800 micrograms/ml (0.05 to 4 mM) was added at the time the lattices were released. Minoxidil at concentrations from 100 to 600 micrograms/ml inhibited contraction in a dose-dependent manner, whereas 800 micrograms/ml prevented contraction completely, most cells remaining rounded. Considerable inhibition was already evident within 24 hours. Visualization of living cells with MTT and cell counts showed that inhibition in the first 48 hours was not due to fibroblast death. Exchange of minoxidil to normal medium led to a resumption of contraction and a return to an elongate morphology. Minoxidil at 10 micrograms/ml had no significant effect on lattice contraction, whereas at 100 micrograms/ml it slowed contraction without affecting proliferation or morphology, as observed under the light microscope. The inhibitory effect of minoxidil should be investigated further in relation to the control of contraction of wounds in vivo.
Antibody response to tetanus toxoid inoculation in malarious and non-malarious Gambian children (1962)

Antibody response to tetanus toxoid inoculation in malarious and non-malarious Gambian children Get access Ian A. McGregor, Ian A. McGregor Medical Research Council Laboratories, Gambia Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Barr M. Barr Wellcome Research Laboratories, Beckenham, England Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 56, Issue 5, September 1962, Pages 364–367, https://doi.org/10.1016/0035-9203(62)90005-6 Published: 01 September 1962
Thermal oxidative degradation reactions of linear perfluoroalkylethers (1983)

Thermal and thermal oxidative stability studies were performed on linear perfluoro alkyl ether fluids. The effect on degradation by metal catalysts and degradation inhibitors are reported. The liner perfluoro alkylethers are inherently unstable at 316 C in an oxidizing atmosphere. The metal catalysts greatly increased the rate of degradation in oxidizing atmospheres. In the presence of these metals in an oxidizing atmosphere, the degradation inhibitors were highly effective in arresting degradation at 288 C. However, the inhibitors had only limited effectiveness at 316 C. The metals promote degradation by chain scission. Based on elemental analysis and oxygen consumption data, the linear perfluoro alkylether fluids have a structural arrangement based on difluoroformyl and tetrafluoroethylene oxide units, with the former predominating.
Nonsolvable finite groups all of whose local subgroups are solvable. II (1970)

In this second paper, the bulk of the work is devoted to characterizing E 2 () and S*(3). These two groups are "almost" -groups and it is relevant to treat them separately. The actual characterizations (Theorems 8.1 and 9.1) are very technical but the hypotheses deal with the structure and embedding in a simple group of certain {2, 3}-subgroups. This paper is a continuation of an earlier paper. 1 The bibliographical references are to I. 7* Groups in which 1 is the only p-signalizer* DEFINITION 7.1. %f*(p) = {S3 | (i) 35 is a subgroup of of type (p, p). (ii) iV(S3) contains a S p -subgroup of .}. HYPOTHESIS 7.1. ( i ) p is a prime and if S3e^*(p), then no i^-subgroup of C(S3) normalizes any nonidentity ^'-subgroup of . (ii) The centralizer of every nonidentity p-subgroup of is psolvable. Lemmas 7.1, 7.2, 7.3 are proved under Hypothesis 7.1. LEMMA 7.1. (i) ^())g^(p). (See Definitions 2.8 and 2.10 of I). (ii) If p^5, then <%f*(p) S gf (p). (iii) Ifp = S and if no element of ^(3) centralizes a quaternion subgroup of , then ^*(3)Sg'(3).
Novel Copper Electroless Plating Process on Ceramic Substrate Using Copper Oxide Particles (2002)

A novel electroless plating process for preparing a copper film on aluminum nitride (AlN) was developed. This process relies on uniform coating of particles onto AlN substrate followed by annealing to form composite oxide layer and Cu particles as the seed for initiating the electroless copper deposition, instead of using Pd catalyst in a conventional electroless plating process. The adhesive strength measured by peel test was more than 4 kg per (kg/4 mm2), much greater than that obtained using conventional electroless plating process. The use of particles is crucial in this novel process for direct interconnection between deposited Cu film and AIN substrate, and the composite oxide layer formed after annealing is suggested to be responsible for high adhesive strength obtained. © 2002 The Electrochemical Society. All rights reserved.
Graph cut segmentation with a global constraint: Recovering region distribution via a bound of the Bhattacharyya measure (2010)

This study investigates an efficient algorithm for image segmentation with a global constraint based on the Bhattacharyya measure. The problem consists of finding a region consistent with an image distribution learned a priori. We derive an original upper bound of the Bhattacharyya measure by introducing an auxiliary labeling. From this upper bound, we reformulate the problem as an optimization of an auxiliary function by graph cuts. Then, we demonstrate that the proposed procedure converges and give a statistical interpretation of the upper bound. The algorithm requires very few iterations to converge, and finds nearly global optima. Quantitative evaluations and comparisons with state-of-the-art methods on the Microsoft GrabCut segmentation database demonstrated that the proposed algorithm brings improvements in regard to segmentation accuracy, computational efficiency, and optimality. We further demonstrate the flexibility of the algorithm in object tracking.
Optimizing YAFFS2 for Small-Sized NAND Device (2009)

Research on embedded file system becomes more important when the mobile devices have a lot of different options: Cramfs, JFFS and the Yet Another Flash File System (YAFFS), etc. Some of them are specially designed for NAND device such as YAFFS. This paper tries to improve the performance when the file system is adapted to the small-sized NAND device.
High Electrocatalytic and Wettable Nitrogen‐Doped Microwave‐Exfoliated Graphene Nanosheets as Counter Electrode for Dye‐Sensitized Solar Cells (2014)

In this paper, high electrocatalytic and wettable nitrogen-doped microwave-exfoliated graphene (N-MEG) nanosheets are used as Pt-free counter electrode (CE) for dye-sensitized solar cells (DSSCs). A low cost solution-based process is developed by using cyanamide (NH2 CN) at room temperature and normal pressure. The pyrrolic and pyridinic N atoms are doped into the carbon conjugated lattice to enhance electrocatalytic activity. N-MEG film having N-doping active sites and large porosity provides a wettable surface to facilitate electrolyte diffusion so that improves fill factor. Moreover, the control of the air exposure time after completing N-MEG film is found to be crucial to obtain a reliable N-MEG CE. A high DSSC efficiency up to 7.18% can be achieved based on N-MEG CE, which is nearly comparable to conventional Pt CE.
Determination of spin-exchange parameters between optically pumped rubidium and<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">Kr</mml:mi></mml:mrow><mml:mprescripts/><mml:mrow/><mml:mrow><mml:mn>83</mml:mn></mml:mrow><mml:mrow/><mml:mrow/></mml:mmultiscripts></mml:mrow></mml:math> (1990)

The spin-exchange rates due to binary collisions and due to the formation of van der Waals molecules between $^{83}\mathrm{Kr}$ nuclei and optically pumped rubidium-metal vapor have been determined using a technique that relies on the simultaneous observation of frequency shifts of nuclear magnetic resonance lines of noble-gas atoms and corresponding frequency shifts of electron paramagnetic resonance lines of alkali-metal atoms. In contrast, earlier studies have relied on the observation of the spin-relaxation rate of either the alkali-metal atoms or the noble-gas atoms.
A review of sunscreens and their adverse reactions. (2005)

Sunscreens are used to protect the skin from harmful effects of ultraviolet (UV) light but they do not completely prevent photocarcinogenesis, photoaging and photoimmunosuppression. They are useful for protection against UVB and short-wave UVA. Complete protection against long-wave UVA has not been achieved. There is no universally accepted method to evaluate UVA protection. Sun protection factor is a simple and internationally used method to compare sunscreen protection against UVB induced erythema. Adverse reactions to sunscreens are not common but they should be considered especially in persons with pre-existing eczematous conditions or photodermatoses. The use of sunscreens has increased steadily over the last decade; as a result, allergy and photoallergy to UV filters are now more frequent than in the past. Sensitization can occur from the various sunscreening agents and from the excipients included in formulations. An overview of sunscreens, their effectiveness, and adverse reactions is presented.