gebhart/patrepeval huggingface dataset:
Description, analysis and prediction of player actions in selected hockey game situations (2009)

Motion is an important cue to the intentions of active agents in environments involving collaboration and competition. We demonstrate this in the domain of ice hockey. We develop a framework to represent and reason about hockey behaviors using as input actual player motion trajectory data tracked from game video and supported by knowledge of hockey strategy, game context and specific player profiles. The raw player motion trajectory data consists of space-time point sequences of forward/backward skating registered to rink coordinates. This is augmented with knowledge of possession of the puck and specific player attributes (e.g., shoots left, shoots right). We focus on the analysis of three clearly identifiable situations: 2-on-l offensive attacks, defensive zone breakouts and power play shots from the point. We use a Finite State Machine (FSM) model to represent our total knowledge of a given situation and develop evaluation functions for primitive hockey behaviors (e.g., pass, shot). Based on the augmented trajectory data, the FSMs and the evaluation functions, we describe what happened in each identified situation, assess the outcome, estimate when and where key play choices were made, and attempt to predict whether better alternatives were available to achieve understood goals. A textual natural language description and a simple 2D graphic animation of the analysis are produced as the output. The graphic animation is useful for interactive visualization and debugging. The textual description also provides potentially useful annotation for large databases of player motion trajectories. The framework is flexible to allow the substitution of different analysis modules and extensible to allow the inclusion of additional hockey situations. We expect that the methodology and the framework can be generalized and applied in other domains, such as soccer, basketball, traffic flow control and people surveillance.
Keratinocyte growth factor enhances urokinase-type plasminogen activator activity in HPV16 DNA-immortalized human uterine exocervical epithelial cells. (1996)

We recently demonstrated that keratinocyte growth factor (KGF), a fibroblast-derived growth factor, induced anchorage-independent growth of HPV16 DNA-immortalized human uterine exocervical epithelial cells (HCE16/3 cell line) in soft agarose assay. We have now studied whether KGF might also regulate the plasminogen activator (PA) system, another transformation parameter related to cell invasiveness. HCE16/3 cells were found to produce urokinase-type PA (uPA) and small amounts of tissue-type PA (tPA) as determined by immunocapture assay. Secretion of both uPA and tPA was increased when HCE16/3 cells were exposed to KGF for 4 h and continued to increase during the next 24 h. The early increase following KGF treatment was presumably mediated by binding of KGF to its receptors. Enhanced secretion of uPA in HCE16/3 cells by KGF was also seen by zymographic analysis and immunofluorescence. According to Northern blotting KGF upregulated the transcription of uPA gene in HCE16/3 cells; the upregulation occurred only after 12 h of KGF treatment, suggesting that stimulation of uPA production by KGF is a biphasic event. As proteolysis is a prerequisite for tumor cell invasion, taken together with our previous results, the present findings suggest that KGF may play an important role in the transition of immortalized uterine cervical epithelial cells from in situ to invasive carcinoma.
A Catalytically Active, Charge-Neutral Rh(I) Zwitterion Featuring a P,N-Substituted “Naked” Indenide Ligand (2003)

The synthesis and characterization of a new class of cationic and zwitterionic Rh(I) complexes, which feature multidentate ligands comprised of donor-functionalized indene or indenide units, are reported. This unusual new ligation strategy provides access to the first charge-neutral [kappa2-P,N]Rh(I) zwitterion, a complex that functions as a catalyst for the C-H/Si-H dehydrogenative coupling of styrene and triethylsilane.
New method for time dependent x-ray absorption studies (1989)

An absorption spectrum containing both the XANES and the EXAFS region can be recorded in several seconds if x-ray monochromators at synchrotron beamlines are scanned continuously. The experimental setups are described in detail. The accuracy of the method up to photon energies of 19 keV is demonstrated. Due to its advantages, the proposed approach may be used as an alternative to the energy dispersive EXAFS method, especially in the case of XANES spectroscopy.
Hexosome and Hexagonal Phases Mediated by Hydration and Polymeric Stabilizer (2007)

In this research, we studied the factors that control formation of GMO/tricaprylin/water hexosomes and affect their inner structure. As a stabilizer of the soft particles dispersed in the aqueous phase, we used the hydrophilic nonionic triblock polymer Pluronic 127. We demonstrate how properties of the hexosomes, such as size, structure, and stability, can be tuned by their internal composition, polymer concentration, and processing conditions. The morphology and inner structure of the hexosomes were characterized by small-angle X-ray scattering, cryo-transmission electron microscope, and dynamic light scattering. The physical stability (to creaming, aggregation, and coalescence) of the hexosomes was further examined by the LUMiFuge technique. Two competing processes are presumed to take place during the formation of hexosomes: penetration of water from the continuous phase during dispersion, resulting in enhanced hydration of the head groups, and incorporation of the polymer chains into the hexosome structure while providing a stabilizing surface coating for the dispersed particles. Hydration is an essential stage in lyotropic liquid crystal (LLC) formation. The polymer, on the other hand, dehydrates the lipid heads, thereby introducing disorder into the LLC and reducing the domain size. Yet, a critical minimum polymer concentration is necessary in order to form stable nanosized hexosomes. These competing effects require the attention of those preparing hexosomes. The competition between these two processes can be controlled. At relatively high polymer concentrations (1-1.6 wt % of the total formulation of the soft particles), the hydration process seems to occur more rapidly than polymer adsorption. As a result, smaller and more stable soft particles with high symmetry were formed. On the other hand, when the polymer concentration is fixed at lower levels (<1.0 wt %), the homogenization process encourages only partial polymer adsorption during the dispersion process. This adsorption is insufficient; hence, maximum hydration of the surfactant head group is reached prior to obtaining full adsorption, resulting in the formation of less ordered hexosomes of larger size and lower stability.
Mild versus severe COVID-19: Laboratory markers (2020)

The number of COVID-19 patients is dramatically increasing worldwide. Treatment in intensive care units (ICU) has become a major challenge; therefore, early recognition of severe forms is absolutely essential for timely triaging of patients. While the clinical status, in particular peripheral oxygen saturation (SpO2) levels, and concurrent comorbidities of COVID-19 patients largely determine the need for their admittance to ICUs, several laboratory parameters may facilitate the assessment of disease severity. Clinicians should consider low lymphocyte count as well as the serum levels of CRP, D-dimers, ferritin, cardiac troponin and IL-6, which may be used in risk stratification to predict severe and fatal COVID-19 in hospitalised patients. It is more likely that the course of the disease will be unfavourable if some or all of these parameters are altered.
Efficient large-scale access control for Internet/intranet information systems (2003)

Access control is a key problem for information processing, especially in a distributed environment such as the Internet and intranet, where a large amount of diverse information resources within an enterprise will be made available for groups of diverse users to query. Information documents such as technology secrets and personal records are sensitive and should be accessible to a select group of users based on their position in a company or an organization or even based on how much the user is paying to maintain his/her right for information access. The access control problem, informally, is to determine which user is allowed to access what information. Access control for Internet information processing, in contrast to access control in a traditional operating system, has higher demand in dealing with a much larger scale problem in real time, due to the large amount of information and number of users in the Internet/intranet environment. We present an efficient method for the access control problem in which there are a large number of users and access groups. The main ingredient of our method is a representation of a hierarchical access group structure in terms of intervals over a set of integers and a decomposition scheme that reduces any group structure to ones that have interval representations. The interval representation allows the problem for checking access rights to be reduced to an interval containment problem. We use the interval tree, a popular data structure in computational geometry, to efficiently execute the access-right checking method.
Differentiation of Truthful and Deceptive Criminal Suspects in Behavior Analysis Interviews (1994)

The Behavior Analysis Interview (BAI) is a commonly used procedure designed to assist investigators in distinguishing between suspects who are concealing their involvement in a criminal event (deceptive) from those who are not (truthful). During a BAI a protocol of questions is asked and suspects' verbal responses and accompanying nonverbal behaviors and attitudinal characteristics are assessed. Based on this assessment the likelihood of involvement in the criminal event is determined. The purpose of this study was to determine the effectiveness with which trained evaluators were able to distinguish between truthful and deceptive suspects undergoing BAIs. Sixty videotaped interviews, 30 of truthful and 30 of deceptive suspects, were observed by four evaluators, each of whom independently scored suspect's behaviors and attitudes and judged the suspect's truthfulness. The results showed that, excluding inconclusive decisions, evaluators' average accuracy on truthful suspects was 91% and on deceptive suspects, 80%. Suspects' status did not affect confidence of evaluators' decisions but confidence was greater when correct as opposed to incorrect calls were made. Deceptive suspects manifested "theoretically" predicted behaviors and attitudes of "deceptiveness" to a significantly greater degree than did truthful suspects. The BAI appears to be useful for investigative purposes in order to differentiate between suspects who are concealing involvement in a criminal offense from those who are not.
[Cloning of the gene for extracellular Bacillus circulans RNAase]. (1994)

The gene for extracellular low molecular weight ribonuclease of Bacillus circulans BCF 247 was cloned. The strain was isolated from permafrost deposits of the Kolyma lowland. The gene for the ribonuclease from Bacillus intermedius (binase) was used as a specific probe. The cloning succeeded only in the E. coli strain producing the inhibitor of ribonuclease form Bacillus amyloliquefaciens. Selected clones secreted the active ribonuclease into the growth media. Deletion derivatives of the parental recombinant plasmid were constructed. The smallest DNA fragment which enclosed a functional ribonuclease gene in E. coli was determined to be 0.6 kb in length.
Murine Typhus: Updated Roles of Multiple Urban Components and a Second Typhuslike Rickettsia (1994)

Studies using serologic and polymerase chain reaction-(PCR) facilitated analysis of field samples from southern Texas indicate the presence of Rickettsia typhi and ELB agent infected cat fleas, Ctenocephalides felis (Bouché), and the first observation of ELB infected vertebrates (opossums). The ELB agent is a recently described typhus-like rickettsia that is not distinguished from R. typhi or R. prowazekii by currently available serologic reagents. Restriction digests of PCR products from 399 fleas revealed an ELB agent infection rate of 3.8% and a R. typhi infection rate of 0.8%. Three of nine tested opossums (Didelphis virginiana) were shown to harbor ELB agent infections. No R. typhi infected rats, Rattus norvegicus, or rat-fleas, Xenopsylla cheopis Rothschild, were detected among surveyed samples. The persistence of this murine typhus disease focus appears to be better accounted for by the presence of infected cat fleas, opossums, and other non-rat hosts found in close association with human populations. Involvement of the ELB agent in the biology of murine typhus is suggested by its prevalence among suspected vectors and reservoir hosts.
<i>IKZF1</i> (Ikaros) Deletions in <i>BCR-ABL1</i> –Positive Acute Lymphoblastic Leukemia Are Associated With Short Disease-Free Survival and High Rate of Cumulative Incidence of Relapse: A GIMEMA AL WP Report (2009)

We conclude that IKZF1 deletions are likely to be a genomic alteration that significantly affects the prognosis of Ph-positive ALL in adults.
The Preparation of 1-C<sup>14</sup>-Labeled Glucose, Mannose and Fructose<sup>1</sup> (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation of 1-C14-Labeled Glucose, Mannose and Fructose1H. G. Hers, J. Edelman, and V. GinsburgCite this: J. Am. Chem. Soc. 1954, 76, 20, 5160–5161Publication Date (Print):October 1, 1954Publication History Published online1 May 2002Published inissue 1 October 1954https://pubs.acs.org/doi/10.1021/ja01649a055https://doi.org/10.1021/ja01649a055research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Noninvasive Detection of <i>HER2</i> Amplification with Plasma DNA Digital PCR (2013)

Analysis of plasma DNA with digital PCR has the potential to screen for the acquisition of HER2 amplification in metastatic breast cancer. This approach could potentially be adapted to the analysis of any locus amplified in cancer.
The Halide Binding Behavior of 2‐Carbamoyl‐7‐ureido‐1<i>H</i>‐indoles: Conformational Aspects (2009)

Abstract Indole‐based anion receptors with an carboxamide unit in 2‐ and an urea in 7‐position were prepared and found to bind halides (as well as acetate and nitrate) in chloroform solutions at room temperature. Investigations of the binding behaviour show that the receptor is selective for chloride. Surprisingly, the truncated receptor 3 without the 2‐carbamoyl substituent shows the highest affinity for Cl – . Thorough 1 H, 13 C and 15 N NMR investigations indicate different binding modes for acetate, nitrate and halides to the receptor 2 . The observation of a major conformational change of this receptor during the binding of the halide ions leads to an understanding of the relative binding affinities of 3 > 4 > 2 for chloride. The results of the NMR study are supported by ab initio calculations. In addition, ESI FTICR MS competition experiments of the indole 2 and the quinoline 1 reveal the “self‐aggregation” of the receptors and show that halides have a higher affinity to 2 than to 1 .(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Hepatic lipase induces the formation of pre-beta 1 high density lipoprotein (HDL) from triacylglycerol-rich HDL2. A study comparing liver perfusion to in vitro incubation with lipases (1994)

High density lipoprotein subfractions with a pre-beta migration play a key role in the reverse cholesterol transport. The origin of these particles is not yet clearly defined. We propose to verify a possible origin of these particles during the catabolism of high density lipoprotein2 (HDL2) by hepatic lipase using two different models. A rat liver perfusion of native human HDL2 in the presence of heparin induced, after 30 min, the formation of the pre-beta 1 HDL subspecies. Human HDL2 enriched with triacylglycerols, perfused in the same conditions, led after 15 min to an enhanced production of this pre-beta 1 HDL population, as compared with the results obtained with native HDL2. A reduction of the alpha-HDL2 fraction was also evident. After perfusion, a similar formation of pre-beta 1 HDL from triacylglycerol-rich HDL2 was observed in absence of heparin. When these HDL2 were incubated in vitro for 120 min at 37 degrees C in the presence of partially purified rat hepatic lipase, the appearance of pre-beta 1 HDL was again found and associated with a decrease in size of the remaining alpha-HDL subfractions as compared with original HDL2. On the contrary, the incubation of the same HDL2 with snake venom phospholipase A2 produced no pre-beta HDL. These results evidence the role of the triacylglycerol lipase activity of hepatic lipase in the formation of pre-beta 1 HDL from triacylglycerol-rich HDL2.
THE S<sub>N</sub> MECHANISM IN AROMATIC COMPOUNDS, PART XI. SOME REACTIONS OF AMINODINITRODIARYL ETHERS (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleTHE SN MECHANISM IN AROMATIC COMPOUNDS, PART XI. SOME REACTIONS OF AMINODINITRODIARYL ETHERSATHELSTAN L. BECKWITH and JOSEPH MILLERCite this: J. Org. Chem. 1954, 19, 10, 1708–1715Publication Date (Print):October 1, 1954Publication History Published online1 May 2002Published inissue 1 October 1954https://pubs.acs.org/doi/10.1021/jo01375a023https://doi.org/10.1021/jo01375a023research-articleACS PublicationsRequest reuse permissionsArticle Views145Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design, Synthesis, and Properties of Highly Efficient Side-Chain Dendronized Nonlinear Optical Polymers for Electro-Optics (2002)

Two novel nonlinear optical side-chain dendronized polymers have been synthesized by using a simple and mild post-functionalization method to graft highly polarizable chromophores bearing crosslinkable dendrons as side chains to poly(4-hydroxystyrene). This approach provides the combined advantages of better poling efficiency through the dendritic effect, and shortened development time required for synthesis. High poling efficiency and good temporal stability at room temperature are indeed demonstrated in these systems.
Role and regulation of phospholipase D signalling (1997)

Conference Article| November 01 1997 Role and regulation of phospholipase D signalling A. Martin; A. Martin *Institute for Cancer Studies, Birmingham University Medical School, Birmingham B15 2TA, U.K. Search for other works by this author on: This Site PubMed Google Scholar K. M. Saqib; K. M. Saqib *Institute for Cancer Studies, Birmingham University Medical School, Birmingham B15 2TA, U.K. Search for other works by this author on: This Site PubMed Google Scholar M. N. Hodgkin; M. N. Hodgkin *Institute for Cancer Studies, Birmingham University Medical School, Birmingham B15 2TA, U.K. Search for other works by this author on: This Site PubMed Google Scholar F. D. Brown; F. D. Brown *Institute for Cancer Studies, Birmingham University Medical School, Birmingham B15 2TA, U.K. Search for other works by this author on: This Site PubMed Google Scholar T. R. Pettit; T. R. Pettit *Institute for Cancer Studies, Birmingham University Medical School, Birmingham B15 2TA, U.K. Search for other works by this author on: This Site PubMed Google Scholar S. Armstrong; S. Armstrong †School of Biological Sciences, Birmingham University, Birmingham B15 2TT, U.K. Search for other works by this author on: This Site PubMed Google Scholar M. J. O. Wakelam M. J. O. Wakelam *Institute for Cancer Studies, Birmingham University Medical School, Birmingham B15 2TA, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1997) 25 (4): 1157–1160. https://doi.org/10.1042/bst0251157 Article history Received: July 31 1997 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation A. Martin, K. M. Saqib, M. N. Hodgkin, F. D. Brown, T. R. Pettit, S. Armstrong, M. J. O. Wakelam; Role and regulation of phospholipase D signalling. Biochem Soc Trans 1 November 1997; 25 (4): 1157–1160. doi: https://doi.org/10.1042/bst0251157 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: ARF, ADP-ribosylation factor, DAG, diacylglycerol, h, human, PA, phosphatidate, PAE, porcine aortic endothelial, PC, phosphatidylcholine, PE, phosphatidylethanolamine, PI, phosphatidylinositol, PIP2, PI 4,5-bisphosphate, PKC, protein kinase C This content is only available as a PDF. © 1997 Biochemical Society1997 Article PDF first page preview Close Modal You do not currently have access to this content.