gebhart/patrepeval huggingface dataset:
Bem‐estar do trabalhador docente de educação física do sul do Brasil (2016)

O objetivo do estudo foi avaliar o nível de associação do bem‐estar do trabalhador docente de educação física a partir dos parâmetros socioambiental (satisfação no trabalho) e individual (estilo de vida) considerando o vínculo no magistério público dos estados da Região Sul do Brasil. Participaram da pesquisa 1.645 docentes, os quais responderam os instrumentos QVT‐PEF e PEVI. Os resultados revelaram elevado índice de professores com alto nível de bem‐ estar. O constructo do estilo de vida apresentou maior número de associações significativas com o vínculo estadual dos docentes, o que demonstra que os fatores ligados aos aspectos ambientais e as políticas que regem a profissão docente de cada estado interferem com maior propriedade nos componentes do parâmetro individual. The aim of the study was to evaluate the level of association of Wellness of the Physical Education Teacher Worker from the Parameters: Socio‐Environmental (Work) and Individual (Lifestyle) considering employment relationship in the public teaching of southern states of Brazil. The 1645 teachers, who participated of the research, answered the instruments QVT‐PEF and PEVI. The results revealed that a high number of teachers had a high level of wellness. The Lifestyle construct presented a higher number of significant associations with the teacher's employment relationship, which demonstrates that the factors related to the environmental aspects and the policies that govern the teaching profession in each state interfere with more property in the aspects related to the Individual Parameter. El objetivo de este estudio fue evaluar el nivel de asociación de bienestar del trabajador docente de educación física a partir de los parámetros socioambiental (trabajo) e individual (estilo de vida) al considerar el vínculo con la docencia pública de los estados de la región sur de Brasil. Participaron en la investigación 1.645 profesores, los cuales respondieron a los instrumentos QVT‐PEF y PEVI. Los resultados revelaron un elevado índice de profesores con alto nivel de bienestar. El constructo estilo de vida presentó un número mayor de asociaciones significativas en la relación con el empleo de los docentes, lo que demuestra que los factores ligados a los aspectos ambientales y las políticas que rigen la profesión docente de cada estado interfieren con mayor propiedad en los componentes del parámetro individual.
Virus-Specific Cytolytic Antibodies to Nonstructural Protein 1 of Japanese Encephalitis Virus Effect Reduction of Virus Output from Infected Cells (2009)

We demonstrate the presence of nonstructural protein 1 (NS1)-specific antibodies in a significant proportion of convalescent-phase human serum samples obtained from a cohort in an area where Japanese encephalitis virus (JEV) is endemic. Sera containing antibodies to NS1 but not those with antibodies to other JEV proteins, such as envelope, brought about complement-mediated lysis of JEV-infected BHK-21 cells. Target cells infected with a recombinant poxvirus expressing JEV NS1 on the cell surface confirmed the NS1 specificity of cytolytic antibodies. Mouse anti-NS1 cytolytic sera caused a complement-dependent reduction in virus output from infected human cells, demonstrating their important role in viral control. Antibodies elicited by JEV NS1 did not cross lyse West Nile virus- or dengue virus-infected cells despite immunoprecipitating the NS1 proteins of these related flaviviruses. Additionally, JEV NS1 failed to bind complement factor H, in contrast to NS1 of West Nile virus, suggesting that the NS1 proteins of different flaviviruses have distinctly different mechanisms for interacting with the host. Our results also point to an important role for JEV NS1-specific human immune responses in protection against JE and provide a strong case for inclusion of the NS1 protein in next generation of JEV vaccines.
Reliability of digital orthodontic setups (2015)

Based on these findings, it can be inferred that digital setups are as effective and accurate as manual setups and constitute a tool for diagnosing and treatment planning that can be reliably reproduced in orthodontic treatments.
Niobium and tantalum derivatives with bidentate nitrogen ligands as potential precursors to nitrides (1999)

Early transition metal derivatives with N-donors have attracted interest as precursors of nitrides, the latter being used as diffusion barriers for the ULSI technology. Potential precursors to niobium and tantalum nitrides have been synthesized in good yields and characterized. They are based on bidentate nitrogen donors namely amidinates, benzamidinates and diamido ligands. These have been reacted with niobium or tantalum derivatives namely penta and tetrachlorides, TaCl 3 (NEt 2 ) 2 . Disubstituted niobium(IV) and tantalum(V) species such as for instance NbCl 2 [RNCR'NR 2 ] 2 [R= Cy, N(SiMe 3 ) 2 ; R = SiMe 3 , R' = p-tolyl] have been obtained and structurally characterized, The more rigid o-dimethylphenylene diamido ligand lead to a volatile, air stable disubstituted Nb(V) species NbCl{N 2 (SiMe 3 ) 2 C 5 H 3 } 2 . However, π-stacking as shown by X-ray studies are responsible of quite low sublimation rates. Thus, volatility could be reached for some species, their properties, high solubility due to the trimethylsilylligands, their stability in solution is more suited for applications in wet MOCVD than conventional one.
Benzophenone‐functionalized, starlike polystyrenes as organic supports for a tridentate bis(imino)pyridinyliron/trimethylaluminum catalytic system for ethylene polymerization (2006)

Abstract Starlike polystyrenes composed of a microgel core and arms terminated with benzophenone groups were used as organic supports for a tridentate bis(imino)pyridinyliron catalyst for ethylene polymerization in the presence of trimethylaluminum as a cocatalyst. The microgels were synthesized by the atom transfer radical polymerization of styrene initiated by 4‐(1‐bromoethyl)‐benzophenone, with divinylbenzene as the crosslinker. The bromine polystyrene chain ends prevented the ethylene polymerization reaction and had to be removed. This was readily achieved with Cu 0 together with dodecanethiol as a transfer agent. When used as supports in the presence of trimethylaluminum and 2,6‐bis[1‐2,6(diisopropylphenyl)imino]ethylpyridynyl iron, these bromine‐free, functionalized polystyrene stars enabled the production of polyethylene beads of a spherical morphology and high bulk density with a catalytic activity similar to that under homogeneous reaction conditions. Moreover, the molar mass distribution of the polyethylene was narrow, suggesting limited transfer to trimethylaluminum. © 2006 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 44: 6997–7007, 2006
Investigation of safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of a long‐acting α‐MSH analog in healthy overweight and obese subjects (2013)

MC4-NN2-0453 is a novel, long-acting, selective, melanocortin-4-receptor agonist developed for treatment of obesity. This first-human-dose, randomized, double-blind, placebo-controlled trial investigated the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of MC4-NN2-0453 in overweight to obese but otherwise healthy subjects. The trial included a single-dose part of ascending subcutaneous 0.03-1.50 mg/kg doses in overweight to obese but otherwise healthy men, and a multiple-dose part of ascending subcutaneous 0.75-3.0 mg/day doses in obese but otherwise healthy men/women. The single-dose part included 7 cohorts of 8 subjects, randomized 6:2 to active drug/placebo; the multiple-dose part included 4 cohorts of 20 subjects, randomized 16:4 to active drug/placebo. MC4-NN2-0453 was well tolerated and raised no safety concerns except for nonserious skin-related adverse events, this along with lack of weight loss effect led to premature termination of the trial. Headache, sexual-arousal disturbance, and penile erection were also reported. Single-dose pharmacokinetics showed dose-linearity and dose-proportionality. Maximum plasma concentration was observed after 50-100 hours, which then declined with a of approximately 250 hours. Plasma concentration reached steady state after 4 weeks for 0.75 and 1.5 mg/day multiple-dose cohorts, and the was similar to single dose. There were no significant pharmacodynamic effects, including effect on body weight.
Antigenic and Molecular Evolution of the Vaccine Strain of Type 3 Poliovirus during the Period of Excretion by a Primary Vaccinee (1986)

A 4 month old child was immunized with a vaccine containing the Sabin live attenuated vaccine strains of all three serotypes of poliovirus. The antigenic and molecular evolution of the Sabin strain of poliovirus type 3 was then followed throughout the entire period of virus excretion. Novel strains appeared at 8, 42 and 52 days post-vaccination and were the products of both intertypic recombination between type 2 and type 3 poliovirus in regions of the genome coding for non-structural proteins and of point mutations in the region coding for the structural proteins. Excretion of virus continued for 73 days. All strains examined reacted with all monoclonal antibodies specific for the main immunodominant antigenic site of type 3 poliovirus, but variation was observed at other, immunorecessive sites. These findings have possible implications for the evolution of the virus in vaccinees or in epidemics and are consistent with the known antigenic stability of the virus.
Clinical presentation and management of neonatal abstinence syndrome: an update (2014)

Abstract: Exposure to prescription medications and illicit drug use during pregnancy has been associated with neonatal abstinence syndrome. The clinical presentation consists of neurological respiratory, gastrointestinal, and vasomotor disturbances. All infants require observation and supportive care to ensure appropriate adaptation and growth in the newborn period. A smaller percentage may also require additional pharmacotherapy, depending on the specific gestational substance exposure. Women should be counseled antenatally about the possible neonatal effects, and mother–baby dyad care should be implemented for this particular patient population. Keywords: neonatal withdrawal, opioids, marijuana, cocaine, benzodiazepines, selective serotonin reuptake inhibitors
Does Copper Dissolution Impact Through-Hole Solder Joint Reliability? (2009)

ABSTRACT The process issues relating to high copper dissolution rates have been well documented within the industry. The copper dissolution rates of SAC305/405 plus many of the leading alternative lead-free wave alloys have been characterized and pin-through-hole rework process windows assessed. One remaining gap within the industry is the understanding of how copper dissolution or thinning of the through-hole barrel wall/knee locations impacts the thermal and mechanical reliability of a pin-through-hole joint. This paper provides a summary of previous work performed to study and characterize the copper dissolution rates of various Pb-free wave alloys, as well as attempts to assess the impact of high levels of copper dissolution on the thermal reliability of a 14 I/O PDIP connector. A total of five PDIP connectors were designed onto a test vehicle, each individually daisy chained using bottomside traces, for in-situ monitoring. A design of experiment was defined as an attempt to vary the level of plated copper remaining after simulating the rework of the five PDIP connectors. Each board was subjected to 0-100°C ATC for 6,000 cycles with in-situ monitoring to detect failures throughout testing using data loggers. The results from this work indicate reliability concerns when a severe degree of copper dissolution occurs and shows signs of reduced reliability due to thinning of the copper plating thickness at the knee location. In addition, mechanical and thermo-mechanical loading are key elements necessary to confirm the reliability of a pinthrough-hole joint, this paper however, focuses on thermal fatigue reliability assessment. Lastly, this paper will highlight limitations of the copper plating measurement methodology used and suggests alternative non-destructive options to inspect for copper dissolution within manufacturing environments.
HDL and cholesterol handling in the brain (2014)

Cholesterol is an essential component of both the peripheral nervous system and central nervous system (CNS) of mammals. Brain cholesterol is synthesized in situ by astrocytes and oligodendrocytes and is almost completely isolated from other pools of cholesterol in the body, but a small fraction can be taken up from the circulation as 27-hydroxycholesterol, or via the scavenger receptor class B type I. Glial cells synthesize native high-density lipoprotein (HDL)-like particles, which are remodelled by enzymes and lipid transfer proteins, presumably as it occurs in plasma. The major apolipoprotein constituent of HDL in the CNS is apolipoprotein E, which is produced by astrocytes and microglia. Apolipoprotein A-I, the major protein component of plasma HDL, is not synthesized in the CNS, but can enter and become a component of CNS lipoproteins. Low HDL-C levels have been shown to be associated with cognitive impairment and various neurodegenerative diseases. On the contrary, no clear association with brain disorders has been shown in genetic HDL defects, with the exception of Tangier disease. Mutations in a wide variety of lipid handling genes can result in human diseases, often with a neuronal phenotype caused by dysfunctional intracellular lipid trafficking.
The Role of Cell Renewal in the Ontogeny of the Intestine. II. Regulation of Cell Proliferation in Adult, Fetal, and Neonatal Intestine (1983)

Department of Anatomy, University of Kansas Medical Center, College of Health Sciences and Hospital, Kansas City, Kansas
Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesisin a mouse model (2004)

Thrombo-occlusive cerebrovascular disease resulting in stroke and permanent neuronal loss is an important cause of morbidity and mortality. Because of the unique properties of cerebral vasculature and the limited reparative capability of neuronal tissue, it has been difficult to devise effective neuroprotective therapies in cerebral ischemia. Our results demonstrate that systemic administration of human cord blood–derived CD34(+) cells to immunocompromised mice subjected to stroke 48 hours earlier induces neovascularization in the ischemic zone and provides a favorable environment for neuronal regeneration. Endogenous neurogenesis, suppressed by an antiangiogenic agent, is accelerated as a result of enhanced migration of neuronal progenitor cells to the damaged area, followed by their maturation and functional recovery. Our data suggest an essential role for CD34(+) cells in promoting directly or indirectly an environment conducive to neovascularization of ischemic brain so that neuronal regeneration can proceed.
Experiment study of PUMA robot calibration using a laser tracking system (2003)

Laser tracking systems (LTS) are among the most accurate robot metrology systems. These laser interferometer systems combine the advantages of high resolution, large work space and contactless measurements. A target mounter on the end-effector of the robot, is automatically tracked by a laser beam targeted by the moving mirror. A prerequisite for utilizing a LTS to calibrate robots is that the LTS itself should be self-calibrated successfully. In this paper, we describe the experimental calibration of a PUMA 560 robot by using a LTS developed at the Robotics Center, Florida Atlantic University. The calibration is based on a prior successful self-calibration of the LTS. Calibration results are analyzed and confirmed using a verification method. This is the first actual calibration of robots using a LTS in the United States during the 20th centenary.
Effects of la concentration on the structural and dielectric properties of 0.57BiFeO/sub 3/-0.43PbTiO/sub 3/ crystalline solutions (2007)

Crystalline solutions of 0.57(Bi(1-x)La(x))FeO(3)-0.43PbTiO(3) (BLF-PT) for x = 0, 0.1, 0.2, and 0.3 were fabricated by the traditional solid state reaction method. X-ray diffraction analysis revealed that the tetragonal torhombohedral phase transformation of BLF-PT occurred with an increase of the La content. The dielectric and ferroelectric properties of BLF-PT were investigated at room temperature for different La contents. BLF-PT revealed strong ferroelectric characteristics for the lower La composition, and transferred to relaxor ferroelectrics for x 0.2. The dielectric constant and remanent polarization were 1461 and 33.5 microC/cm(2), respectively, for BLF-PT of x = 0.2. The dielectric constant and polarization of BLF-PT were enhanced simultaneously with increasing La content. Our results demonstrate that BLF-PT is a competitive piezoelectric ceramic.
GIS를 이용한 광주지역의 토양오염 우려지역에 대한 토양오염도 평가 및 시각화 연구 (2020)

To make the assessment of soil contamination in Gwangju, we conducted an analysis from 2014 to 2018 about 22 factors as the Korean Soil Contamination Warning Standards. According to the results, we also visualized the soil contamination point map in each sampling site. The average concentration are below the Korean Soil Contamination Warning Standards. As a results of contamination assessment by land use, the major contaminants are arsenic in railroad-related facilities and railroad tie area and nikel in shooting range-related facilities area. The soil pollution index (SPI) of heavy metals on total 459 sites showed 87.8 % of 1st level (good condition), 8.7 % of 2nd level (concern for contamination), 1.5 % of 3rd level (concern for contamination), and 2.0 % of 4th level (considered as contaminated). In case of point contaminant concentration distribution in each items, 72 % of cadmium was below 1.0 mg/kg, 90 % of arsenic was below 1.0 mg/kg, 91 % of copper and lead were below 50.0 mg/kg respectively, 60 % of nikel was below 10.0 mg/kg, 92 % of mercury was below 0.1 mg/kg, 68 % of TPH was below 100 mg/kg and 43 % of fluorine was below 200 mg/kg.
Hebbian Learning in Spiking Neural Networks With Nanocrystalline Silicon TFTs and Memristive Synapses (2011)

Characteristics similar to biological neurons are demonstrated in SPICE simulations of spiking neuron circuits comprised of submicron nanocrystalline silicon (nc-Si) thin-film transistors (TFTs). Utilizing these neuron circuits and corresponding device models, the properties of a two-neuron network are explored. The synaptic connection consists of a single nc-Si TFT and a memristor whose conductance determines the synaptic weight. During correlated spiking of the pre- and postsynaptic neurons, the strength of the synaptic connection increases. Conversely, it is diminished when the spiking is uncorrelated. This synaptic plasticity and Hebbian learning are essential for performing useful computation and adaptation in large-scale artificial neural networks. The importance of the result is augmented by the fact that these properties are demonstrated using models based on measured data from devices with potential for 3-D integration into a nanoscale architecture with extremely high device density.
Beta-Blockade Lowers Peripheral Lipolysis in Burn Patients Receiving Growth Hormone (1996)

The administration of propranolol to burned children receiving rhGH is safe, has salutary cardiovascular effects, decreases the release of FFA from adipose tissue and increases the efficiency of the liver in secreting fatty acids as VLDL TGs.
Genomic Sequencing Reveals Mutations Potentially Related to the Overattenuation of a Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus (2013)

Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) continues to evolve when serially passaged in Marc-145 cells. In this study, we analyzed the genomic and antigenic variants of HP-PRRSV strain JXA1 during in vitro passage. Protective efficacies of JXA1 from passages 100, 110, 120, 140, and 170 against the high-virulence parental virus were evaluated by inoculating pigs with each of these viruses and then challenging with JXA1 from passage 5 at 28 days postimmunization. We found that the antigenicities of JXA1 from passages after 110 were significantly reduced. Inoculation with JXA1 from passages after 110 provided only insufficient protection against the parental strain challenge, indicating that the immunogenicity of JXA1 is significantly decreased when it is in vitro passaged for 110 times and more. To identify the genomic variants that emerged during the overattenuation, eight complete genomes of highly passaged JXA1 were sequenced. One guanine deletion in the 5' untranslated region (UTR), two nucleotide substitutions in the 3' UTR, and 65 amino acid mutations in nonstructural and structural proteins that accompanied with the attenuation and overattenuation were determined. Genomic sequencing of in vitro serially passaged HP-PRRSV first identified the mutations potentially correlated with the overattenuation of a HP-PRRSV strain. These results facilitate the research aimed at elucidating the mechanisms for PRRSV genomic and antigenic changes and may also contribute to developing a safe and effective PRRSV vaccine.
A double-blind comparison of the efficacy and safety of milnacipran and fluoxetine in depressed inpatients (1998)

This double-blind, randomised, multicentre study compared the antidepressant efficacy and safety of two doses of milnacipran (100 mg/day and 200 mg/day) and fluoxetine (20 mg/day) in 289 inpatients with endogenous depression. After a placebo washout period of 4-7 days, assessments were performed weekly during the first 4 weeks, and then after 6, 8 and 12 weeks, using the 17-item Hamilton Depression Rating Scale (HDRS), the Montgomery-Asberg Depression Rating Scale (MADRS) and the Clinical Global Impression (CGI). HDRS total score was reduced by a mean of 14.8 in the milnacipran 100 mg/day group, 12.9 in the milnacipran 200 mg/day group and 12.1 in the fluoxetine 20 mg/day group. MADRS total score decreased by 17.4, 15.8 and 14.6, respectively. No significant difference could be shown between the three treatment groups for either the HDRS or MADRS total scores. However, the time-by-time change showed a trend in favour of milnacipran 100 mg/day, which was found significantly superior to fluoxetine at day 28 for several converging parameters (MADRS, CGI-3). Overall, efficacy ratings for all parameters were highest for milnacipran 100 mg/day, followed by milnacipran 200 mg/day and fluoxetine 20 mg/day. Side-effect profiles were not significantly different between groups except for a significantly greater frequency of dose-related increase in heart rate > or = 100 bpm in milnacipran recipients and a significantly greater weight loss in fluoxetine recipients.
Wide Band Video Signal Recorder Having Level and Linearity Corrector (1986)

Extensive works are now being carried out on the development of band compression techniques for the transmission of the high definition TV (HD-TV), which would be practiced in future by utiIizing one of the channels of 12 GHz band satellite broadcastings. In this, the bandwidth of HD-TV signal which occupies the bandwidth several times that of the present system, is compressed to less than 9 MHz. By making use of the above techniques. it is desired to provide a new video signal recorder with the capability of 9 M Hz band recordings.