gebhart/patrepeval huggingface dataset:
Highly selective decomposition of methanol to syngas on nickel-based composite catalysts using an artificial intelligence control reactor system (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHighly selective decomposition of methanol to syngas on nickel-based composite catalysts using an artificial intelligence control reactor systemYoshiaki Nakazaki and Tomoyuki InuiCite this: Ind. Eng. Chem. Res. 1989, 28, 9, 1285–1289Publication Date (Print):September 1, 1989Publication History Published online1 May 2002Published inissue 1 September 1989https://pubs.acs.org/doi/10.1021/ie00093a003https://doi.org/10.1021/ie00093a003research-articleACS PublicationsRequest reuse permissionsArticle Views191Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Aginactin, an agonist-regulated F-actin capping activity is associated with an Hsc70 in Dictyostelium. (1993)

We have previously isolated an agonist-regulated actin filament capping activity, called aginactin, that is associated with a 70-kDa protein (Sauterer, R. A., Eddy, R. J., Hall, A. L., and Coneelis, J. S. (1991) J. Biol. Chem. 266, 24533-24539). A 2.0-kilobase clone isolated from a Dictyostelium lambda gt11 cDNA library screened with affinity-purified aginactin antibodies displays an overall sequence identity of 73% to the 70-kDa heat shock cognate protein, Hsc70, from various species. Aginactin capping activity and the 70-kDa protein bind to ATP-agarose columns and are quantitatively depleted from the load, indicating that an Hsc70 is associated with aginactin activity. Moderate stringency Southern blots indicate the presence of no fewer than six Hsc70-related sequences. Immunofluorescent staining of vegetative Dictyostelium AX3 cells with aginactin antibodies reveals a colocalization of aginactin-associated Hsc70 in F-actin-rich regions of the cell cortex and cell protrusions. Nuclei and organelles lacked positive staining indicating that the aginactin-associated Hsc70 is cytosolic. The levels of cytoskeletal-associated Hsc70 correlate with the loss of barbed end capping activity following cAMP stimulation, suggesting that the uncapping of barbed filament ends through an Hsc70-associated process may account for the increase in nucleation activity observed at 5 s following agonist stimulation.
Expression of differentially expressed nucleolar transforming growth factor‐β1 target (DENTT) in adult mouse tissues (2002)

Differentially expressed nucleolar TGF-beta1 target (DENTT) is a novel member of the TSPY/TSPY-L/SET/NAP-1 (TTSN) superfamily that we have previously identified in human lung cancer cells. Here, we have investigated the expression of this protein in the adult mouse. By Western analysis, DENTT is highly expressed in the pituitary gland and moderately in the adrenals, brain, testis, and ovary. Immunohistochemical staining analysis for DENTT showed differential cytoplasmic and nuclear staining patterns in several cell types. The pituitary gland showed the highest level of immunostaining for DENTT, with strong cytoplasmic immunoreactivity in the anterior lobe, moderate levels in the posterior lobe, and a few cells showing nuclear staining in the intermediate lobe. In contrast, the intermediate lobe of the pituitary showed intense cytoplasmic staining for TGF-beta1. Nuclear and cytoplasmic staining for DENTT was present in the islets of Langerhans in the pancreas. Cytoplasmic staining for DENTT was particularly intense in the cortex of the adrenal gland, whereas the medulla showed weak nuclear staining. In the nervous system, the choroid plexus showed the highest immunoreactivity, with cortical motoneurons and Purkinje cells having relatively high levels of staining for DENTT as well. DENTT immunoreactivity was found in Leydig interstitial cells, Sertoli cells, and primary spermatocytes in the testis. In the female reproductive system, DENTT immunoreactivity was present in oocytes, thecal cells, and corpora lutea. The bronchial epithelium of the lung showed moderate levels of staining for DENTT localized to the cell nucleus. Additionally, three rodent pituitary cell lines (AtT20, GH3, and alphaT3-1, representing corticotropes, lactotropes, and gonadotropes, respectively) showed expression of DENTT. Addition of TGF-beta1 or serum to AtT20 cells increased DENTT protein production by 4 hr and, after reaching maximal levels at 2.4-fold above basal level by 8 hr, decreased, whereas no more than a 1.5-fold increase in DENTT protein occurred in GH3 or alphaT3-1 cells. Transient transfection studies showed that ectopic DENTT expression significantly increased the level of p3TP-Lux reporter transcription in AtT20 cells, but not in GH3 or alphaT3-1 cells. Interestingly, addition of TGF-beta1 had no significant effect on the ability of DENTT expression to influence p3TP-Lux reporter transcription in AtT20 cells. This report is the first detailed immunohistochemical examination of a member of the TTSN superfamily in the adult mouse. Expression of DENTT in endocrine tissues, nervous system, lung, oocytes, and thecal cells, in addition to the testis, suggests new roles for the TTSN superfamily. The differential patterns of expression of DENTT and TGF-beta1 in some tissues, including the pituitary, suggest that other factors are likely to be regulators of DENTT besides TGF-beta1.
Changes in Heart Rate Variability in Chronic Uremic Patients during Ultrafiltration and Hemodialysis (2001)

Chronic uremics showed abnormal autonomic modulation with sympathetic-vagal imbalance. The unbalanced hypersympathetic response to body fluid depletion is related to the ultrafiltration rate. Low interdialytic weight gain and a low ultrafiltration rate, associated with adequate hemodialysis, should be the preferable strategy for uremic patients with autonomic dysfunction.
Photosynthetic biomass and H<sub>2</sub> production by green algae: from bioengineering to bioreactor scale‐up (2007)

The development of clean borderless fuels is of vital importance to human and environmental health and global prosperity. Currently, fuels make up approximately 67% of the global energy market (total market = 15 TW year(-1)) (Hoffert et al. 1998). In contrast, global electricity demand accounts for only 33% (Hoffert et al. 1998). Yet, despite the importance of fuels, almost all CO(2) free energy production systems under development are designed to drive electricity generation (e.g. clean-coal technology, nuclear, photovoltaic, wind, geothermal, wave and hydroelectric). In contrast, and indeed almost uniquely, biofuels also target the much larger fuel market and so in the future will play an increasingly important role in maintaining energy security (Lal 2005). Currently, the main biofuels that are at varying stages of development include bio-ethanol, liquid carbohydrates [e.g. biodiesel or biomass to liquid (BTL) products], biomethane and bio-H(2). This review is focused on placing bio-H(2) production processes into the context of the current biofuels market and summarizing advances made both at the level of bioengineering and bioreactor design.
Matrix type transdermal therapeutic systems of glibenclamide: Formulation, <i>ex vivo</i> and <i>in vivo</i> characterization (2011)

Matrix type transdermal therapeutic systems (TTS) of glibenclamide were formulated using polymers Eudragit RL 100, ethyl cellulose, PVP K-30, and polyvinyl acetate, and citral was used as the penetration enhancer. The polymer films were formulated with Eudragit RL 100 and PVP K-30 in different ratios and subsequently subjected to ex vivo studies (drug permeation through rat skin) followed by interaction studies, skin irritation studies, accelerated stability analysis, and in vivo studies (determination of blood glucose level in rabbits). The drug content of the formulations was found to be 99.1-99.2%. The cumulative percentages of drug permeated through rat skin from the three selected formulations in 48 h were 95.3%, 98.8%, and 99%, respectively. A plot between cumulative percent of drug permeated and square root of time exhibited linear curves, which suggests the Higuchian matrix mechanism of drug release. The formulation containing Eudragit RL 100 and PVP K-30 showed better improvement in hypoglycemic activity in rabbits (56.2-60.8% reduction in blood glucose level, p < 0.05). There were fewer fluctuations in blood glucose level as compared to oral therapy due to controlled release of the active pharmaceutical ingredient, and no interaction was found between the drug and excipients of the formulation. Accelerated stability analysis showed that the formulation was stable up to 5.5 years, with negligible skin irritation. The formulation precluded severe hypoglycemic reactions (side effect of sulfonylureas) and was effective for management of diabetes mellitus up to 48 h, with a single TTS.
Lattice Absorption in Gallium Arsenide (1961)

A series of detailed measurements of the lattice absorption bands of gallium arsenide has been made over the wavelength range 10–40 μ and over the temperature range 20–292°K. These results can be interpreted in terms of multiple phonon interactions involving five characteristic phonon energies. These results, along with the known elastic constants, have enabled us to supply all the relevant data for a computation of the complete phonon spectrum using an extension of the shell model.
Proposal of a Kinect<sup>TM</sup>-based system for gait assessment and rehabilitation in Parkinson's disease (2014)

It has been proved that audio and visual cueing can improve the motor performance of Parkinson's disease patients. Specially, gait can benefit from repetitive sessions of exercises using cues. Nevertheless, these effects are not permanent and fade away with time, in that sense, home game systems can be an excellent platform for patients to perform daily exercises, as well as to coach and guide them in a smarter way. Within this work a method to track the walking movement is proposed based on the signals coming from the Kinect sensor of Microsoft. At the same time, different setups have been tested in order to study the feasibility of using this sensor to build a game platform for gait rehabilitation for Parkinson's disease patients.
A TOTP-Based Enhanced Route Optimization Procedure for Mobile IPv6 to Reduce Handover Delay and Signalling Overhead (2014)

Due to the proliferation of handheld mobile devices, multimedia applications like Voice over IP (VoIP), video conferencing, network music, and online gaming are gaining popularity in recent years. These applications are well known to be delay sensitive and resource demanding. The mobility of mobile devices, running these applications, across different networks causes delay and service disruption. Mobile IPv6 was proposed to provide mobility support to IPv6-based mobile nodes for continuous communication when they roam across different networks. However, the Route Optimization procedure in Mobile IPv6 involves the verification of mobile node's reachability at the home address and at the care-of address (home test and care-of test) that results in higher handover delays and signalling overhead. This paper presents an enhanced procedure, time-based one-time password Route Optimization (TOTP-RO), for Mobile IPv6 Route Optimization that uses the concepts of shared secret Token, time based one-time password (TOTP) along with verification of the mobile node via direct communication and maintaining the status of correspondent node's compatibility. The TOTP-RO was implemented in network simulator (NS-2) and an analytical analysis was also made. Analysis showed that TOTP-RO has lower handover delays, packet loss, and signalling overhead with an increased level of security as compared to the standard Mobile IPv6's Return-Routability-based Route Optimization (RR-RO).
Chemotherapy targeting cancer stem cells. (2015)

Conventional chemotherapy is the main treatment for cancer and benefits patients in the form of decreased relapse and metastasis and longer overall survival. However, as the target therapy drugs and delivery systems are not wholly precise, it also results in quite a few side effects, and is less efficient in many cancers due to the spared cancer stem cells, which are considered the reason for chemotherapy resistance, relapse, and metastasis. Conventional chemotherapy limitations and the cancer stem cell hypothesis inspired our search for a novel chemotherapy targeting cancer stem cells. In this review, we summarize cancer stem cell enrichment methods, the search for new efficient drugs, and the delivery of drugs targeting cancer stem cells. We also discuss cancer stem cell hierarchy complexity and the corresponding combination therapy for both cancer stem and non-stem cells. Learning from cancer stem cells may reveal novel strategies for chemotherapy in the future.
Track-before-detect procedures in a multi-target environment (2008)

This paper addresses the problem of early detection of K ges 1 multiple moving targets in radar systems through the use of track-before-detect (TBD) techniques. At first, assuming prior knowledge of K, a binary generalized likelihood ratio test (GLRT) is derived, which shows that the multi-target TBD problem can be regarded as a K-path trellis search. Since optimal implementation of the GLRT has a nonlinear complexity either in the number of targets or in the number of integrated frames, suboptimum algorithms are investigated which allow to trade better estimation and tracking accuracy for a much lower implementation complexity. Next, the TBD problem with K unknown is discussed and a novel multi-hypothesis test strategy is derived as the solution to a constrained optimization problem, which subsumes the conventional binary GLRT as the special case of known K. Finally, numerical examples are provided to assess and compare the performances of the proposed TBD procedures.
New insights into the role of NK cells in cancer immunotherapy (2012)

Repetitive infusions of ex vivo expanded NK cells induced antitumor T-cell responses in a metastatic lung cancer mouse model. These were further potentiated by Treg depletion. Thus the combination of NK cell-based immunotherapy with other treatment modalities in the direction of adaptive response enhancement might promote long lasting antitumor immunity.
Primary tumors of the heart (2016)

Before referring a patient with cardiac tumor to the cardiac surgeon, a presumptive diagnosis of benignity or malignancy should be obtained. Malignant tumors should be referred to a cardiac tumor team with special expertise, in order to plan the best therapeutic approach.
Ignitor Plug Operation in a Pulsed Plasma Thruster (1982)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
New aspects of the role of histamine in cardiovascular function: identification, characterization, and potential pathophysiological importance of H<sub>3</sub>receptors (1995)

As a result of intensive research during several decades, the distribution, function, and pathophysiological role of cardiovascular H1 and H2 receptors are well known, whereas reports on the occurrence and function of H3 receptors in blood vessels and the heart have not become available before the last 7 years (i.e., 4 years after the first description of these receptors in the central nervous system in 1983). The development of selective and potent H3 receptor agonists and antagonists was a prerequisite for convenient investigations of cardiovascular H3 receptors, which like H1 and H2 receptors are G-protein coupled but unlike them have not yet been cloned. Both in blood vessels and the heart, H3 receptors are located on noradrenergic nerve endings and upon stimulation mediate an inhibition of noradrenaline release. Whereas it remains to be clarified under which conditions the vascular H3 receptors may be stimulated by endogenous histamine, those in the heart become activated in the early phases of myocardial ischemia characterized by an increased histamine spillover. The H3 receptors in the central nervous system also appear to be of importance for the control of vascular function. Inhibitory presynaptic H3 receptors occur on trigeminal sensory C fibres supplying blood vessels in the dura mater. Release of neuropeptides from these fibres induces a neurogenic inflammation, which has been suggested to be involved in the pathogenesis of migraine. An interaction, involving presynaptic H3 receptors, between sensory C fibres and mast cells in close apposition to these fibres plays a role in the control of histamine synthesis in the dura mater.(ABSTRACT TRUNCATED AT 250 WORDS)
The acute effects of synthetic intravenous Δ<sup>9</sup>-tetrahydrocannabinol on psychosis, mood and cognitive functioning (2009)

These findings confirm that THC can induce a transient, acute psychotic reaction in psychiatrically well individuals. The extent of the psychotic reaction was not related to the degree of anxiety or cognitive impairment.
Long-term Oxygen Therapy: Indications and Guidelines for Use (1989)

Kathryn L. Anderson, RN, MN, worked for several years as a respiratory clinical nurse specialist at Seattle- King County Visiting Nurse Services. She is currently a lecturer at Seattle University School of Nursing, and continues to work in home health each summer
Semiconductor laser simulations using non-equilibrium Green’s functions (2012)

We present a novel method to simulate quantum well, edge-emitting semiconductor lasers in non-equilibrium steady-state. Our method is based on non-equilibrium Green’s functions approach which allows for a fully quantum mechanical description of carrier and photon dynamics. This microscopic approach significantly reduces the number of phenomenological parameters needed to simulate laser. General equations for photon Green’s functions and polarizations are derived as well as their coupling to electron Green’s functions through self-energies. Series of approximations are done to photon Green’s function to allow for efficient numerical approach. All equations are written in the non-orthogonal basis suitable for numerical calculations. As an example, the theory is applied to analyze Al0.2Ga0.8As/GaAs quantum well laser with the effective mass Hamiltonian. Major laser characteristics such as material and modal gain, threshold parameters, carrier and current densities were determined.
Data representation and feature selection for colorimetric sensor arrays used as explosives detectors (2011)

Within the framework of the strategic research project Xsense at the Technical University of Denmark, we are developing a colorimetric sensor array which can be useful for detection of explosives like DNT, TNT, HMX, RDX and TATP and identification of volatile organic compounds in the presence of water vapor in air. In order to analyze colorimetric sensors with statistical methods, the sensory output must be put into numerical form suitable for analysis. We present new ways of extracting features from a colorimetric sensor and determine the quality and robustness of these features using machine learning classifiers. Sensors, and in particular explosive sensors, must not only be able to classify explosives, they must also be able to measure the certainty of the classifier regarding the decision it has made. This means there is a need for classifiers that not only give a decision, but also give a posterior probability about the decision. We will compare K-nearest neighbor, artificial neural networks and sparse logistic regression for colorimetric sensor data analysis. Using the sparse solutions we perform feature selection and feature ranking and compare to Gram-Schmidt orthogonalization.
2-(2-Methoxyphenylsulfanyl)benzoic acid (2006)

The title compound, C14H12O3S, was synthesized from 2-methoxy­thio­phenol and 2-chloro­benzoic acid with copper powder as catalyst. In the mol­ecule, the two benzene ring planes are roughly perpendicular. The mol­ecules are linked through an inversion center by O—H⋯O hydrogen bonds, forming a pseudo-dimer.
On-Chip Thermionic Electron Micro-Emitter Arrays Based on Carbon Nanotube Films (2020)

On-chip electron sources with high electron-emitting performance and small footprint are of great interest in vacuum nanoelectronics. Resembling traditional thermionic emission sources based on a hot tungsten filament, Joule-heated carbon nanotube can function as filament material of nanoscale electron source because of its excellent thermal stability and electrical conductivity. Here, we demonstrate the fabrication of high-performance on-chip thermionic electron micro-emitter arrays by utilizing microfabrication technologies and exploiting suspended carbon nanotube arrays as thermionic filaments.1 For single micro-emitter, an electron emission density up to <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\approx 1.33$</tex> A <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\text{cm}^{-2}$</tex> is obtained at a low-driven voltage <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$(\approx 4\mathrm{V})$</tex> . The turn-on/off time is measured to be less than <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$1\ \mu \mathrm{s}$</tex> , because thermal inertia of filament is greatly reduced compared with their bulky counterparts. Particularly, stable <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$(\pm 1.2\%$</tex> ) emission current fluctuation for 30 min) and reproducible <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$(\pm 0.2\%$</tex> driven voltage variation over 27 cycles) electron emission have been experimentally observed under a low vacuum of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\approx 5\times 10^{-4}$</tex> Pa. Even under a rough vacuum of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\approx 10^{-1}$</tex> Pa, an impressive reproducibility ( <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$\pm 2\%$</tex> driven voltage variation over 20 cycles) is obtained. Moreover, emission performances of micro-emitter arrays are found to exhibit good uniformity in wafer scale. The outstanding stability, reproducibility and uniformity of our carbon nanotube based thermionic electron micro-emitter imply their promising applications as on-chip integrated electron sources.