gebhart/patrepeval huggingface dataset:
Rational Design of Macrometallocyclic Trinuclear Complexes with Superior π-Acidity and π-Basicity (2008)

Density functional theory (DFT) has been used to assess the pi-acidity and pi-basicity of metal-organic trimetallic macromolecular complexes of the type [M(mu-L)]3, where M = Cu, Ag, or Au and L = carbeniate, imidazolate, pyridiniate, pyrazolate, or triazolate. The organic compounds benzene, triazole, imidazole, pyrazole, and pyridine were also modeled, and their substituent effects were compared to those of the coinage metal trimers. Our results, based on molecular electrostatic potential surfaces and positive charge attraction energy curves, indicate that the metal-organic macromolecules show superior pi-acidity and -basicity compared to their organic counterparts. Moreover, the metal-organic cyclic trimers are found to exhibit pi-acidity and -basicity that can be systematically tuned both coarsely and finely by judicious variation of the bridging ligand (relative pi-basicity imidazolate > pyridiniate > carbeniate > pyrazolate > triazolate), metal (relative pi-basicity Au > Cu > Ag), and ligand substituents. These computational findings are thus guiding experimental efforts to rationally design novel [M(mu-L)]3 materials for applications in molecular electronic devices that include metal-organic field-effect transistors and light-emitting diodes.
Embedded-mask-methods for mm-scale multi-layer vertical/slanted Si structures (2002)

Complicated deep-etched structures having multiple heights and vertical/slanted walls have realized by fully-silicon-based batch fabrication process, which only needs lithography on a flat surface. Arbitrary numbers of mask layers were laminated on the initial surface of a substrate and deep-RIE, LOCOS or anisotropic wet etching were performed to make microstructures using each mask layer subsequently.
Atrial natriuretic factor receptors and stimulation of cyclic GMP formation in normal and malignant osteoblasts (1986)

Synthetic rat atrial natriuretic factor (Ile-ANF-26) stimulated cyclic GMP formation by up to several hundred-fold in osteoblast-rich cultures from newborn rat calvaria and in clonal osteogenic sarcoma cells (UMR 106-01) which are phenotypically osteoblast. ANF had no effect on the cyclic AMP response to parathyroid hormone in the same cells. Specific, high-affinity binding sites for ANF were identified in both cell types, with Kd and receptor numbers in normal osteoblasts of 1.2 +/- 0.1 X 10(-10) M and 42 +/- 4 X 10(3) per cell, and in UMR 106-01 cells of 1.4 +/- 0.1 X 10(-10) M and 22 +/- 4 X 10(3) per cell.
Centralized versus Distributed Index Schemes in OODBMS-A Performance Analysis (1997)

Recent work on client-server data-shipping OODBs has demonstrated the usefulness of local data caching at client sites. In addition to data caching, index caching can provide substantial benefits through associative access to cached objects. Indexes usually have high contention, and database performance is quite sensitive to the index management scheme. This paper examines the effects of two index caching schemes, one centralized and the other distributed, for index page management in a page server OODB. In the centralized scheme, index pages are not allowed to be cached at client sites and are managed by the server. The distributed index management scheme supports inter-transaction caching of index pages at client sites, and enforces a distributed index consistency control protocol similar to that of data pages. We study via simulation the performance of these two index management schemes under several different workloads and contention profiles, and identify scenarios where each of the two schemes performs better than the other.
Ets-1 expression in vascular endothelial cells as an angiogenic and prognostic factor in colorectal carcinoma. (2003)

We investigated Ets-1 expression and its influence on angiogenesis and survival using immunohistochemistry of surgical specimens from 95 patients of colorectal cancer. The expression rate of Ets-1 was 48.4% of all cases in cancer cells, 65.3% in endothelial cells, and 28.4% in stromal cells. The microvessel density in patients with vascular Ets-1 expression was significantly higher than that in patients without the expression. A significant positive correlation was discovered between the Ets-1 vascular expression and vascular endothelial growth factor (VEGF) expression, or pyrimidine nucleoside phosphorylase (dThdPase) activity in the tumor. The positivity of vascular Ets-1 expression was higher in node-positive patients and in M1 patients. The survival rate was significantly lower in those cases positive for vascular Ets-1. Angiogenic factors such as VEGF might be involved in tumor angiogenesis through the Ets-1 vascular expression. The Ets-1 vascular expression may be a prognostic factor for colorectal cancer.
New trends in very low bitrate video coding (1995)

The interest in very low birate video coding has increased considerably with the creation of new services and applications requiring this class of bitrates in their function. This paper aims in presenting the current problems and requirements, as well as the efforts in very low bitrate video coding. It also provides a number of solutions in order to solve these problems and to fulfill desired requirements in very, low bitrate coding. The main emphasis was given to an approach called "second generation" which has already shown its potential to efficiently code still images at higher compression factors. In particular, three techniques will be discussed in details, because of their ability to successfully achieve very low bitrate video coding with a reasonably good quality. The simulation results obtained by these techniques under the exact same conditions are presented and the merits and drawbacks of each one are pointed out throughout the paper.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
MEMS Inertial Sensor Toward Higher Accuracy & amp; Multi-Axis Sensing (2006)

This paper reports MEMS inertial sensor which is based on the principle of a rotational gyroscope can detect both 3-axis acceleration and 2-axis angular rate at a time by electrostatically suspending and rotating rotor in the shape of a ring made from silicon. The device has several advantages: the levitation of the rotor in a vacuum eliminates a mechanical friction resulting in high sensitivity; the position control for the levitation allows to sense accelerations in tri-axis. Latest measurements yield noise level of gyro and that of accelerometer as low as 0.002deg/s/Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">frac12</sup> and 20 muG/Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">frac12</sup> , with 1.5mm diameter rotor at 74,000rpm
Transverse spectral velocity estimation (2014)

A transverse oscillation (TO)-based method for calculating the velocity spectrum for fully transverse flow is described. Current methods yield the mean velocity at one position, whereas the new method reveals the transverse velocity spectrum as a function of time at one spatial location. A convex array probe is used along with two different estimators based on the correlation of the received signal. They can estimate the velocity spectrum as a function of time as for ordinary spectrograms, but they also work at a beam-to-flow angle of 90°. The approach is validated using simulations of pulsatile flow using the Womersly-Evans flow model. The relative bias of the mean estimated frequency is 13.6% and the mean relative standard deviation is 14.3% at 90°, where a traditional estimator yields zero velocity. Measurements have been conducted with an experimental scanner and a convex array transducer. A pump generated artificial femoral and carotid artery flow in the phantom. The estimated spectra degrade when the angle is different from 90°, but are usable down to 60° to 70°. Below this angle the traditional spectrum is best and should be used. The conventional approach can automatically be corrected for angles from 0° to 70° to give fully quantitative velocity spectra without operator intervention.
Left ventricular assessment using real time three dimensional echocardiography (2003)

The ability to accurately assess left ventricular function non-invasively is essential for patient management since it has been known for years that left ventricular ejection fraction serves as an important predictor of long term survival. Although two dimensional (2D) echocardiography is routinely used in clinical practice to obtain information on left ventricular dimension, wall thickness, and function, this technique is limited because it relies heavily on geometrical assumptions to provide quantitative parameters of left ventricular function. In order to avoid these geometrical constraints, three dimensional (3D) reconstructions of the left ventricular cavity have been performed over the last 30 years using a variety of method.

Although multiple studies have validated the superiority of 3D over 2D echocardiography to assess left ventricular function, 3D methods have not been embraced in clinical practice because of the cumbersome methodology used to date for both data acquisition and analysis. This manuscript will review prior 3D techniques used to quantitate left ventricular function and present an overview of the recently introduced matrix array transducer capable of generating real-time 3D transthoracic echocardiographic images.

Estimations of left ventricular volumes were first performed using M mode echocardiography. Published data using this unidimensional technique reported a large volume discrepancy between this methodology and angiographic data. Although 2D echocardiography has improved left ventricular volume calculations, underestimations are still frequently reported when compared with gold standard methods such as angiography and magnetic resonance imaging (MRI).1–4

Three separate steps are required to assess left ventricular function using 3D echocardiography: (1) data acquisition, (2) image processing, and (3) data analysis. Acquisition of a 3D volume dataset may be obtained with a variety of methods such as free-hand scanning using mechanical or non-mechanical locators, gated sequential acquisition methods, and sparse and full matrix array transducers capable of obtaining real time data sets. …
Identification of Thiazolidinones Spiro‐Fused to Indolin‐2‐ones as Potent and Selective Inhibitors of the <i>Mycobacterium tuberculosis</i> Protein Tyrosine Phosphatase B (2010)

The best of 40 000: Detailed structure–activity-relationship studies revealed key structural elements of indolin-2-on-3-spirothiazolidinones (see example) and their appropriate configuration for strong inhibitory activity against the pathophysiologically relevant title protein. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Adaptive search range motion estimation using neighboring motion vector differences (2011)

This paper presents a new fast motion estimation method where search ranges are determined by the probabilities of motion vector differences (MVDs). The MVDs' distribution is investigated and its parameter is estimated by the maximum likelihood estimator. With the estimated distribution, the search ranges are efficiently restricted by a prefixed probability for MVDs. Experimental results show that the performance of the proposed method is very similar to that of the full search algorithm in PSNR but it enables significant reduction in the computational complexity.
Seismic data acquisition and processing using measured motion signals on vibrators (1998)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1998Seismic data acquisition and processing using measured motion signals on vibratorsAuthors: Keith WilkinsonRichard HabiakArt SiewertGraham MillingtonKeith WilkinsonEnertec Geophysical, Richard HabiakEnertec Geophysical, Art SiewertMobil Oil Canada, and Graham MillingtonMobil Oil Canadahttps://doi.org/10.1190/1.1820182 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1820182FiguresReferencesRelatedDetailsCited ByDynamic phase compensation for Non-linear Vibroseis using "Phase Only" signature deconvolution.*Art Siewert, Paul Hewitt, and Scott Hess19 August 2015How technology drives high-productivity vibroseis: a historical perspective30 April 2012 | Geophysical Prospecting, Vol. 60, No. 4Source measurement effect on high fidelity vibratory seismic separationGeophysical Prospecting, Vol. 58, No. 1Orthogonal vibroseis sweepsGeophysical Prospecting, Vol. 53, No. 5 SEG Technical Program Expanded Abstracts 1998ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1998 Pages: 2092 publication data© 1998 Copyright © 1998 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 06 Jan 2005 CITATION INFORMATION Keith Wilkinson, Richard Habiak, Art Siewert, and Graham Millington, (1998), "Seismic data acquisition and processing using measured motion signals on vibrators," SEG Technical Program Expanded Abstracts : 144-146. https://doi.org/10.1190/1.1820182 Plain-Language Summary PDF DownloadLoading ...
An Interaction between a-Actinin and the / 1 Integrin Subunit In Vitro (2013)

Abstract. A number of cytoskeletal-associated proteins that are concentrated in focal contacts, namely ot-actinin, vinculin, talin, and integrin, have been shown to interact in vitro such that they suggest a potential link between actin filaments and the membrane. Because some of these interactions are of low affinity, we suspect that additional linkages also exist. Therefore, we have used a synthetic peptide corresponding to the cytoplasmic domain of/3 ~ integrin and affinity chromatography to identify additional integrinbinding proteins. Here we report our finding of an interaction between the cytoplasmic domain of/3 ~ integrin and the actin-binding protein ot-actinin. /3~-integrin cytoplasmic domain peptide columns bound several proteins from Triton extracts of chicken embryo
Photodynamic therapy involves an antiangiogenic mechanism and is enhanced by ferrochelatase inhibitor in urothelial carcinoma (2013)

The purpose of the present study was to investigate the mechanism of photodynamic therapy (PDT) supplemented with exogenously added 5-aminolevulinic acid (ALA) on human urothelial cancer (UC). Moreover, we aimed to determine whether the therapeutic effects of ALA-based PDT (ALA-PDT) for UC could be enhanced by deferoxamine (DFX), an inhibitor of ferrochelatase. The efficiency of ALA-PDT on these cells was analyzed using flow cytometry and the type of cell death was also assessed. The ALA-PDT promoting effect of DFX was examined on both UC cells and human umbilical vein endothelial cells (HUVEC). The ALA-PDT decreased levels of mitochondrial membrane potential and induced cell death mainly via apoptosis in these cells. Moreover, inhibition of ferrochelatase by DFX led to an increase of protoporphyrin IX (PpIX) accumulation and enhanced the effect of ALA-PDT on UC cells. We further investigated the effect of DFX on in vivo PDT with a tumor-bearing animal model and found that DFX efficiently enhanced tumor cell apoptosis. ALA-PDT induced death of neovascular endothelial cells in tumors but did not affect small vessel endothelial cells in normal tissues surrounding the tumor. Furthermore, DFX enhanced inhibition of neovascularization. These results demonstrated ALA-PDT dominantly induced apoptosis over necrosis by direct action on UC as well as via antiangiogenic action on neovacular endothelial cells, suggesting that the therapeutic damage by ALA-PDT could be kept to a minimum in the surrounding normal tissues. In addition, increased accumulation of PpIX by DFX could enhance this effectiveness of ALA-PDT.
Surface modification of lignocellulosic fibres in atmospheric air pressure plasma (2007)

New applications of lignocellulosic fibres have been driven by numerous factors, including pressure from environmental groups, stringent environmental laws, waste minimisation efforts, recycling and cost reduction initiatives and responsible social awareness. However, the exploitation of such fibres in, for instance, fibre-reinforced composites or in the textile industry is hindered by the presence of waxy layers on the surfaces of lignocellulosic fibres. Many surface treatments are traditionally used to optimise the surface properties of natural fibres. A potential and environmentally sound surface treatment regards the use of atmospheric air pressure plasma (AAPP). The surfaces of various lignocellulosic fibres were modified using AAPP. We investigated the effect of AAPP treatment duration (i.e. 1 min and 3 min) on the surface properties of the lignocellulosic fibres using wetting and electrokinetic measurements. The critical surface tension of the untreated and AAPP-treated fibres was determined from wetting measurements using the capillary rise technique, whereas the changes in the surface chemistry were characterised by means of zeta (ζ)-potential measurements. A slight increase in the critical surface tension of the lignocellulosic fibres was found with prolonged treatment time, with the exception of abaca fibres. The post-treated fibres show a larger degree of hydrophilicity measured from the difference, Δζ, in the decay of the ζ-potential measured as function of time, with the exception of hemp fibres. Finally, ζ-potential measurements as function of pH validated the performance of both AAPP treatments.
Secure Computer Systems: Mathematical Foundations (1973)

Set theory, Mathematical models, Computer information security, Computer privacy, Computer security, Systems theoryThe paper reports the first results of an investigation into solutions to problems of security in computer systems; it establishes the basis for rigorous investigation by providing a general descriptive model of a computer system. Borrowing basic concepts and constructs from general systems theory, the authors formed a basic result concerning security in computer systems, using precise notions of 'security' and 'compromise'. The authors also demonstrate how a change in requirements can be reflected in the resulting mathematical model. A lengthy introductory section is included in order to bridge the gap between general systems theory and practical problem solving.
The predominant protein in human seminal coagulate (1985)

The predominant protein in human seminal vesicle secretion constitutes the structural protein of coagulated semen. This high molecular weight protein (HMW-SV-protein) is stable in seminal vesicle secretion during in vitro storage at 37 degrees C for at least 20 h, but is rapidly cleaved on mixing with prostatic proteases. Seminal coagulate, washed free of soluble components, is dissoluble by 2 to 3 mol/l of guanidine-HCl. Although dithiothreitol added to seminal coagulate does not liquefy the clot, complexes between HMW-SV-proteins are broken up by reduction under denaturing conditions, which suggests that the non-covalent linkages of HMW-SV-proteins are essential in the clot. Prostatic proteases cleave the HMW-SV-protein during liquefaction of ejaculated semen to a series of labile proteins. These proteins are further cleaved to peptides of successively decreasing size after completed liquefaction. The cleavage of the HMW-SV-protein is the major cause of the fast shift of the electrophoretic pattern of seminal proteins if semen is stored without protease inhibitors.
DFC: accelerating string pattern matching for network applications (2016)

Middlebox services that inspect packet payloads have become commonplace. Today, anyone can sign up for cloud-based Web application firewall with a single click. These services typically look for known patterns that might appear anywhere in the payload. The key challenge is that existing solutions for pattern matching have become a bottleneck because software packet processing technologies have advanced. The popularization of cloud-based services has made the problem even more critical.

This paper presents an efficient multi-pattern string matching algorithm, called DFC. DFC significantly reduces the number of memory accesses and cache misses by using small and cache-friendly data structures and avoids instruction pipeline stalls by minimizing sequential data dependency. Our evaluation shows that DFC improves performance by 2.0 to 3.6 times compared to state-of-the-art on real traffic workload obtained from a commercial network. It also outperforms other algorithms even in the worst case. When applied to middlebox applications, such as network intrusion detection, anti-virus, and Web application firewalls, DFC delivers 57-160% improvement in performance.
Mobile Robot Map Updating Using Attributed Fuzzy Tournament Matching (1990)

The maintenance of a map of a mobile robot's surroundings is essential to its autonomous operation. The decision on when to add, delete or modify the abstacle descriptions should be made frequently. These decisions are based on the comparison of sensory data (vision, ultrasonic or laser interferometry) with a-priori information in the map. In this paper, the attributed fuzzy tournaments are suggested as a nonlinear data structure to represent the uncertainty in the contents of the map and the sensory data. An algorithm to compute the level of match between the map and the perceived image of the surrounding obstacles is introduced.
Chemische Untersuchungen zum Abbau vernetzter Phenol‐Formaldehyd‐Harze (1980)

Abstract Neben der Pyrolyse und dem Abbau mit überhitztem Wasserdampf wird insbesondere die hydrogenolytische Spaltung ausgehärteter Phenol‐Formaldehyd‐Harze in Gegenwart von Wasserstoff‐Donatoren untersucht. Als H‐Donor wird hierbei 1,2,3,4‐Tetrahydronaphthalin (Tetralin) eingesetzt, das bei Temperaturen um 400°C unter Wasserstoff‐Transfer an die dispergierten Harzpartikel zu Naphthalin rearomatisiert. Bei maximalen Ausbeuten von insgesamt 98 Gew.‐% (bez. auf die eingesetzte Harzmenge) Phenol, Methylphenolen und oligomeren phenolischen bruchstücken wird eine Nutzung technischer Phenolharzabfälle unter Gewinnung verwertbarer Spaltprodukte diskutiert. Anhand von Abbau‐Kurven und rasterelektronenmikroskopischen Untersuchungen wird auf den Mechanismus der extraktiven hydrogenolytischen Phenolharzverflüssigung eingegangen.
Fluorescence Activated Cell Sorting for Enzymatic Activity (2006)

Directed evolution is a reliable method for protein engineering and as a tool for investigating structure/function relationships. A key for a successful directed evolution experiment is oftentimes the screen. Fluorescence activated cell sorting (FACS) is powerful high-throughput screening approach to isolate and identify mutants from large protein libraries. FACS has been successful in isolating proteins with improved or altered binding affinity. However, FACS screening for mutants with enhanced catalytic activity has been met with limited success. This review focuses on the FACS screening of protein libraries for enzymatic activity.