gebhart/patrepeval huggingface dataset:
Design Verification Program of SMART (2003)

Since July of 1997, KAERI (Korea Atomic Energy Research Institute) has been developing an advanced reactor called SMART(System integrated Modular Advanced ReacTor). SMART is a 330MWt integral type pressurized water reactor that can be used for cogeneration, district heating and seawater desalination as well as electricity generation. Safety enhancement and economic improvement are the two most important considerations in the design of the SMART. The SMART design combines firmly established commercial reactor design technologies with advanced design features. Most of the technologies and design features implemented into the SMART have been proven in industries and advanced design features and technologies have been proven or qualified through SMART design verification program. SMART design verification program includes basic thermal-hydraulic experiments, separate effect test on major components, integrated tests of safety system. The overall performance and safety of SMART will be demonstrated through the one fifth scaled SMART-pilot plant. In June of 2002, SMART Research and Development Center was launched for SMART-pilot plant construction project. The first phase will focus on the design optimization and technology verification by way of tests and experiments, and the second phase to construct SMART-P plant will carry out detailed design and complete the construction by 2008
Toxicity testing with animal viruses: I. Vaccinia virus growth as a model system for teratogens. (1988)

A simple, rapid, inexpensive test for teratogens has been developed using vaccinia virus growth in primate cell cultures. Eighty-four percent of the test compounds that are known to produce teratogenesis in laboratory animals, prevented the formation of viable virus at dosages that did not cause any observable cytotoxicity to uninfected cells. The virus test had one false positive and 5 false negatives out of 74 test compounds. Moreover, the 50% inhibitory dose in vitro (RD50) was significantly correlated (p less than 0.001) with the in vivo, lowest reported teratogenic dose (LTD). The RD50 was not correlated with the in vivo lethal dose (LD50). Thus the virus test appears to be more sensitive to development than to general toxicity. A comparison of the in vitro RD50 with the in vivo, rodent LTD indicated that the two tests were equally predictive of human teratogenesis.
Passive Feed Network Designs for Microfluidic Beam-Scanning Focal Plane Arrays and Their Performance Evaluation (2015)

Microfluidic focal plane arrays (MFPAs) have been recently introduced to implement compact high-gain beam-scanning antennas without resorting to active RF devices. This beam-scanning technique relies on a patch antenna element that can be microfluidically repositioned at the focal plane of a microwave lens. The feed network is strategically designed to be passive and accommodate the position variation in the antenna element. This paper, for the first time, considers the design details and performance evaluation of three different passive network layouts that can potentially be utilized to excite MFPAs. Specifically, resonant corporate, resonant straight, and nonresonant straight microstrip line feed networks are introduced and their loss/bandwidth performances are investigated using the transmission line theory. In addition, a method of moments and ray tracing-based hybrid analysis is utilized to demonstrate the impact of the proposed feed networks on the radiation properties of the MFPA in terms of realized gain and side lobe levels (SLLs). It is shown that the resonant and nonresonant straight microstrip line feed networks reduce the SLL by more than 10 dB relative to the resonant corporate feed network utilized in the prior work. The performance improvements are experimentally verified through an eight-element extended hemispherical dielectric lens-based MFPA prototype. Different than the recent work that relied on liquid metal, the antenna element of this MFPA is implemented from a metalized plate by carrying out flow characterizations on various microfluidic channel geometries. This metalized plate approach paves the way for reliable liquid-metal-free microfluidic reconfigurable devices with higher efficiency and power-handling capabilities.
Stereo- and Regioselective Introduction of 1- or 2-Hydroxyethyl Group via Intramolecular Radical Cyclization Reaction with a Novel Silicon-Containing Tether. An Efficient Synthesis of 4‘α-Branched 2‘-Deoxyadenosines<sup>1</sup> (1998)

An efficient method for the synthesis of 4'alpha-branched 2'-deoxyadenosines starting from 2'-deoxyadenosine has been developed utilizing a novel radical cyclization reaction with a silicon tether. The radical reaction of 4'beta-(phenylseleno)-3'-O-diphenylvinylsilyl adeninenucleoside derivative 17 with Bu(3)SnH and AIBN, followed by Tamao oxidation, gave selectively either the 4'alpha-(2-hydroxyethyl) derivative 21 or 4'alpha-(1-hydroxyethyl) derivative 19, depending on the reaction conditions. With a lower Bu(3)SnH concentration, the reaction gave the 4'alpha-(2-hydroxyethyl) derivative 21, via a 6-endo-radical cyclized product 20, as the sole product in 72% yield. The reaction of 17 in the presence of excess Bu(3)SnH gave 19 quantitatively, via a 5-exo-cyclized product 18, as a diastereomeric mixture. The reaction mechanism was examined using Bu(3)SnD. The results demonstrated that the 5-exo cyclized (3-oxa-2-silacyclopentyl)methyl radical (C) was formed initially which was trapped when the concentration of Bu(3)SnH(D) was high enough. With lower concentrations of Bu(3)SnH(D), radical C rearranged into the ring-enlarged 4-oxa-3-silacyclohexyl radical (D) which was then trapped with Bu(3)SnH(D) to give endo-cyclized product F.
INFLUENCE OF MIXING TECHNOLOGY ON FRESH CONCRETE PROPERTIES OF HPFRCC (2006)

A main issue of a wider application for HPFRCC is a reliable transfer of production processes from laboratory into practice considering the specific boundary conditions in conventional plants for ready mixed concrete or prefabrication. Within a research project the influence of mixing technology on the fresh concrete properties of HPFRCC was investigated. Therefore, the effect of mixing period, intensity and order, including breaks was observed in order to find out how these parameters affect in general the fresh HPFRCC. During the mixing process the temperature of mixtures, engine speed, engine output, energy consumption etc. were recorded and graphed constantly. The measurements were carried out in the laboratory. It was shown that the HPFRCC mixtures could be produced methodically and reproducibly which is essential for the acceptance of these “high-tech” materials in practice.
Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus of the tractus solitarius of the rat (1993)

Whole-cell voltage-clamp recordings were made in thin transverse slices from neurons of the dorsomedial subdivision of the nucleus of the tractus solitarius (NTS) of the rat. Cells were exposed to either the ionotropic glutamate receptor agonist (R, S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) or the GABAA receptor agonist muscimol via pressure ejection directed at the cell soma. The metabotropic glutamate receptor agonist 1S,3R-1-aminocyclopentane-1,3-dicarboxylate (1S,3R-ACPD; 2-100 microM) reversibly depressed muscimol-evoked currents. Conversely, 1S,3R-ACPD reversibly potentiated AMPA-evoked currents. High-frequency stimulation of the tractus solitarius in the presence of 6,7-dinitroquinoxaline-2,3-dione and D-2-amino-5-phosphonopentanoic acid also produced a reversible depression of muscimol-evoked currents that was occluded in the presence of 100 microM 1S,3R-ACPD. 8-Br-cGMP or brain-derived natriuretic peptide mimicked the effects of 1S,3R-ACPD on AMPA and muscimol currents. However, agents that mimicked the actions of cAMP or diacylglycerol did not. These findings indicate that metabotropic glutamate receptors may mediate multiple components of excitatory transmission in the NTS including modulation of glutamate and GABA-activated ion channels.
A convenient and efficient conversion of diethyl [[[2‐(3‐ or 4‐pyridinyl)‐4‐pyrimidinyl]amino]methylene]propanedioates to higher homologs by base‐catalysed transesterification (1984)

Abstract Base‐catalysed transesterification of diethyl [[[2‐(3‐ or 4‐pyridinyl)‐4‐pyrimidinyl]amino]methylene]propanedioates gave higher homolog esters in high yields.
ECG/VCG Rhythm Diagnosis Using Statistical Signal Analysis-I. Identification of Persistent Rhythms (1978)

In this paper we describe a technique for detection and classification of cardiac arrhythmias for ECG or VCG data. The approach is based on the use of R-R interval data and the development of simple models that describe the sequential behavior of such intervals characteristic of different arrhythmias which persist over a period of about six or more heartbeats. In the second part of this two-paper series, we will deal with arrhythmias that manifest themselves as abrupt changes in the observed R-R intervals.
DNA Sequences from a Fossil Termite in Oligo-Miocene Amber and their Phylogenetic Implications (1992)

DNA was extracted from the fossil termite Mastotermes electrodominicus preserved in Oligo-Miocene amber (25 million to 30 million years old). Fragments of mitochondrial [16S ribosomal DNA (rDNA)] and nuclear (18S rDNA) genes were amplified by polymerase chain reaction. Phylogenetic analysis of fossil and extant 18S rDNA confirmed morphological cladistic analyses of living dictyopterans (termites, cockroaches, and mantids). The fossil termite shares several sequence attributes with Mastotermes darwiniensis. Addition of this fossil to living-species phylogeny is required to substantiate Mastotermes monophyly and affects molecular phylogenetic hypotheses of termites in this, the oldest DNA yet characterized.
3,5,3′-Triiodothyronine (T<sub>3</sub>) Receptor-Auxiliary Protein (TRAP) Binds DNA and Forms Heterodimers with the T<sub>3</sub>Receptor (1991)

Nuclear factors enhance binding of T3 receptors (TR) to DNA, suggesting that T3 action may require a multicomponent complex bound to thyroid hormone response elements (TREs). We refer to the 65,000 Da nuclear protein in GH3 cells that enhances TR binding to DNA as the TR-auxiliary protein (TRAP) and have characterized its interaction with TR. Using a TRE-DNA affinity matrix we show that TRAP is able to bind to DNA, even in the absence of functional TR. We then used carboxyl-terminal truncations of rat TR alpha-1 and human TR beta in the avidin-biotin complex DNA-binding assay to identify regions that are important for interaction with TRAP. Removal of 34 residues of hTR beta abolishes T3-binding activity, but the ability to bind TRAP is retained. Further truncations and point mutations suggest that TRAP interacts with the ligand-binding domain of TR and with an independent region which overlaps a conserved sequence adjacent to the second Zn2+ finger (amino acids 120-149 in rTR alpha-1). A fragment of rTR alpha-1 (alpha C291) which encompasses these two regions inhibits the ability of TRAP to enhance TR binding to DNA. This is due to binding of alpha C291 to TR, demonstrating the ability of TR to form homodimers. The inability of TRAP to interact with TR dimers and the similarity of the locations of the estradiol receptor dimerization domains with the TRAP interaction regions lead us to conclude that TRAP stabilizes TR binding to DNA by formation of TRAP-TR heterodimers with both proteins bound to the DNA. TR bound to the estrogen response element is unable to respond to TRAP and unable to stimulate transcription, possibly due to the absence of TRAP in the TR-estrogen response element complex. In addition, TRAP may interact with a certain subset of the nuclear receptor superfamily, since human retinoic acid receptor-beta and vitamin D receptor show increased binding to TREs in the presence of nuclear extract, but c-erbA alpha-2, a variant TR, does not respond to TRAP.
H. 264 Decoder at HD Resolution on a Coarse Grain Dynamically Reconfigurable Architecture (2007)

The eXtreme Processing Platform (XPP) is a new runtime-reconfigurable data processing architecture. It is based on a scalable array of coarse grained computing elements and a packet oriented communication network. The strength of XPP originates from the combination of array processing with unique, powerful runtime-reconfiguration mechanisms. Parts of the array can be configured rapidly in parallel while neighboring computing elements are processing data. Reconfiguration is triggered by internal event signals, or by a Function Processing Array Element (FNC-PAE). The XPP-III architecture is designed to support pipelining and parallelism: instruction-level, data-flow and task-level parallelism. The control flow is handled by multiple VLIW like processors which are closely coupled to the reconfigurable array. Therefore this technology is very well suited for multimedia, telecommunications, graphics and similar stream-based applications with data and control flow. This paper presents the performance of H.264/AVC decoder on XPP-III. The simulation results are very encouraging and allow up to HD (1920x1080@ 24fps) decoding on the XPP-III architecture.
Requirement for CD44 in proliferation and homing of hematopoietic precursor cells (1996)

The hematopoietic form of the adhesion molecule CD44 is known to be involved in lymphocyte maturation and homing. To define lineage and stage of maturation, which requires expression of CD44, murine long-term bone marrow cultures were established. Stroma formation and proliferation of early as well as committed erythroid, myeloid, and lymphoid progenitors were evaluated under the influence of monoclonal anti-CD44 antibodies. Although the formation of stromal elements was not affected, formation of cobblestone areas was completely abolished. [3H]thymidine suicide confirmed that anti-CD44 treatment interfered with the proliferation of early and committed hematopoietic progenitor cells. In addition, homing and seeding of bone marrow cells was impaired by anti-CD44. The data are indicative of a dual functional mode of CD44 in adhesion and proliferation of hematopoietic progenitors and confirm an essential requirement for the molecule in early stages of hematopoiesis.
Rabbit cationic protein enhances leukocyte adhesiveness (1981)

Cationic protein purified from rabbit peritoneal polymorphonuclear leukocytes (PMN) was demonstrated to incite autoaggregation of the rabbit PMN and promote adhesiveness of human PMN to endothelial cells. PMN aggregation induced by supernatants derived from secretory PMN was blocked by a specific anticationic protein antibody. These studies reveal that a positively charged protein derived from the PMN can alter surface properties of the PMN itself and imply a role for this protein in PMN immobilization at inflammatory sites.
Relaxed Cross-lingual Projection of Constituent Syntax (2011)

We propose a relaxed correspondence assumption for cross-lingual projection of constituent syntax, which allows a supposed constituent of the target sentence to correspond to an unrestricted treelet in the source parse. Such a relaxed assumption fundamentally tolerates the syntactic non-isomorphism between languages, and enables us to learn the target-language-specific syntactic idiosyncrasy rather than a strained grammar directly projected from the source language syntax. Based on this assumption, a novel constituency projection method is also proposed in order to induce a projected constituent treebank from the source-parsed bilingual corpus. Experiments show that, the parser trained on the projected treebank dramatically outperforms previous projected and unsupervised parsers. 1
Is it asthma or COPD? (2005)

Evaluation and diagnosis of obstructive lung disease call for careful history taking to distinguish asthma from chronic obstructive pulmonary disease (COPD). A history of atopy and intermittent, reactive symptoms points toward a diagnosis of asthma, whereas smoking and advanced age are more indicative of COPD. Clinical features such as cough and wheezing, especially in light of patient history, can be suggestive but are not definitive. Spirometry, usually performed in the primary care setting, is the key diagnostic tool that distinguishes patients with asthma from patients with COPD. In this article, the authors outline an approach to differential diagnosis of asthma and COPD that should result in better evaluation, therapy, and quality of life for these patients.
Cigarette Smoke Causes Physiologic and Morphologic Changes of Emphysema in the Guinea Pig (1990)

To investigate the long-term effect of cigarette smoke on pulmonary structure and function, we exposed groups of guinea pigs to the smoke of 10 cigarettes each day, 5 days per week, for 1, 3, 6, and 12 months. We found that the guinea pigs developed progressive lung destruction (emphysema) and alterations in their pulmonary function tests similar to that seen in humans with cigarette smoke-induced chronic obstructive lung disease. This method of smoke-induced lung destruction should provide a good model for the study of the early changes of emphysema.
Airborne Demonstration of a Quantum Key Distribution Receiver Payload (2017)

We demonstrate the viability of components of a quantum receiver satellite payload by successfully performing quantum key distribution in an uplink configuration to an airplane. Each component has a clear path to flight for future satellite integration.
Synthesis of 7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylates: the olivanic acid ring system (1979)

The β-lactams prepared from penta-1,4-diene and cyclohexa-1,4-diene by reaction with chlorosulphonyl isocyanate can be readily converted into the 7-oxo-1-azabicyclo[3.2.0]hept-2-ene ring system, using an intramolecular Witting reaction to form the 2,3-double bond.
Polyclonal activation of immature B cells by preactivated T cells: the role of IL-4 and CD40 ligand (1993)

It is well-established that preactivated CD4+ T cells can activate mature B cells in a polyclonal, MHC-unrestricted fashion. We have used this system to investigate the effects of T cell-derived signals on immature B cells purified from the spleens of neonatal mice, since these cells are unresponsive to many polyclonal activators and are exquisitely sensitive to tolerization. We show that immature B cells can be induced to proliferate by anti-CD3 activated, fixed Th1 and Th2 cells, although the latter induce a greater response than the former. Antibodies to IL-4 partially blocked stimulation by Th2 cells, whereas antibodies to IL-2 and IL-5 had no effect on responses to Th1 cells. This suggested that molecules in addition to IL-4 contribute to the capacity of T cells to induce B cell activation, one likely candidate being the ligand for CD40. We therefore generated mouse erythroleukemia (MEL) transfectants which express CD40 ligand (CD40L). These transfectants also induced proliferation of immature B cells, which is enhanced by IL-4. Unlike the situation with mature B cells, both anti-mu and anti-delta antibodies inhibited the activation of immature B cells by CD40L-MEL cells. However, this inhibition was reversed by IL-4, which synergized with signals delivered through CD40 to render immature B cells refractory to negative signals delivered through sIg. Taken together these data suggest that immature B cells can be activated by T cell-derived contact signals and that CD40L-CD40 interactions, in the presence of IL-4, are capable of abrogating the negative signals generated via sIgM and sIgD receptors expressed by these cells.
Standby power management for a 0.18μm microprocessor (2002)

Static power dissipation is a concern for battery powered hand-held devices since it can substantially impact the battery life. Here, the use of reverse body bias to limit Ioff on the high performance, low power XScale™ microprocessor core is described. The scheme utilized is amenable to implementation on a low-cost (non-triple well) process and has limited regulation requirements. The regulation requirements and circuits are described, as is the performance of the method. A measured current reduction factor of over 25 is achieved with this method of reverse body bias. Implications of the use of body bias leakage control for active power and performance, as well as system level implications are also discussed.
An efficient block-oriented approach to parallel sparse Cholesky factorization (1993)

The authors explore the use of a sub-block decomposition strategy for parallel sparse Cholesky factorization, in which the sparse matrix is decomposed into rectangular blocks. Such a strategy has enormous theoretical scalability advantages over more traditional column-oriented and panel-oriented decompositions. However, little progress has been made in producing a practical sub-block method. The authors propose and evaluate an approach that is simple to implement, provides slightly higher performance than column (and panel) methods on small parallel machines, and has the potential to provide much higher performance on large parallel machines.
Solute-solvent interactions in perfluorocarbon solutions of oxygen. An NMR study (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolute-solvent interactions in perfluorocarbon solutions of oxygen. An NMR studyM'Hamed Ali Hamza, Guy Serratrice, Marie Jose Stebe, and Jean Jacques DelpuechCite this: J. Am. Chem. Soc. 1981, 103, 13, 3733–3738Publication Date (Print):July 1, 1981Publication History Published online1 May 2002Published inissue 1 July 1981https://pubs.acs.org/doi/10.1021/ja00403a020https://doi.org/10.1021/ja00403a020research-articleACS PublicationsRequest reuse permissionsArticle Views723Altmetric-Citations88LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A 3-mW 74-dB SNR 2-MHz continuous-time delta-sigma ADC with a tracking ADC quantizer in 0.13-/spl mu/m CMOS (2005)

A third-order continuous-time multibit (4 bit) /spl Delta//spl Sigma/ ADC for wireless applications is implemented in a 0.13-/spl mu/m CMOS process. It is shown that the power consumption can be considerably reduced by using a tracking ADC composed of three comparators with interpolation instead of using a 4-bit flash quantizer. Moreover, the usage of a tracking ADC opens the door to a new forward-looking dynamic element matching (DEM) technique, which helps to reduce the loop delay time and consequently improves the loop stability. The SNR is 74 dB over a bandwidth of 2 MHz. The ADC consumes 3 mW from a 1.5-V supply when clocked at 104 MHz. The active area is 0.3 mm/sup 2/.