gebhart/patrepeval huggingface dataset:
<b>Basicities of the Methyl Benzenes. II. Induction in the L.C.A.O.-M.O. Framework</b> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBasicities of the Methyl Benzenes. II. Induction in the L.C.A.O.-M.O. FrameworkS. EhrensonCite this: J. Am. Chem. Soc. 1962, 84, 14, 2681–2687Publication Date (Print):July 1, 1962Publication History Published online1 May 2002Published inissue 1 July 1962https://pubs.acs.org/doi/10.1021/ja00873a007https://doi.org/10.1021/ja00873a007research-articleACS PublicationsRequest reuse permissionsArticle Views20Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A comparison of rotation-based methods for iterative reconstruction algorithms (1996)

Rotation-based projectors and backprojectors offer unique trade-offs between accuracy, computational complexity, and smoothing. The authors analyzed six different rotation methods for generating projections and iterative reconstructions of tomographic data. Nearest neighbor, upsampled nearest neighbor, bilinear interpolation, and bicubic interpolation were all used to determine the values at rotated grid points. A decomposition of the rotation transformation matrix into three components was also investigated. Linear and cubic interpolation were used in the three-pass method. For all of the methods, mean normalized square errors were computed. The authors' results demonstrate the tradeoffs associated with the different methods and suggest that the three-pass method with cubic interpolation offers a computationally efficient approach with accuracy between that of bilinear and bicubic interpolation.
A synthetic mimetic of CD4 is able to suppress disease in a rodent model of immune colitis (1999)

CD4 + mucosal T cells mediate the intestinal inflammation in Crohn's disease and may serve as an important target for immune intervention.Here we assessed the therapeutic effect of a synthetic mimetic of CD4 designed to mimic both the sequence and conformation of the complementarity-determining region 3 of murine CD4 V1 domain (rD-mPGPtide) in a mouse colitis model using immunization with 2,4,6-trinitrobenzene sulfonic acid (TNB).i. v. administration of the rD-mPGPtide but not control scrambled peptide could suppress severe inflammation in the chronic colitis mouse model.After treatment with the rD-mPGPtide, a striking improvement of diarrhea and acute wasting disease was observed with decreased mortality.Serum anti-TNB antibody titers, CD45RB low CD4 + T cells in the lamina propria and IFN-+ mRNA expression in the mucosa were significantly decreased with the rD-mPGPtide treatment.Anti-CD4 antibody also suppressed disease by depletion of CD45RB high CD4 + T cells in the colonic mucosa.The observation that the synthetically engineered analogue of murine CD4 inhibits inflammation in a rodent disease model by different mechanisms than anti-CD4 antibody suggests that a human version of this peptide has potential therapeutic utility in CD4 + mucosal T cell-mediated intestinal inflammation in Crohn's disease.
Cloud-Based Collaborative Road-Damage Monitoring with Deep Learning and Smartphones (2022)

Road damage such as potholes and cracks may reduce ride comfort and traffic safety. This influence can be prevented by regular, proper monitoring and maintenance of roads. Traditional methods and existing methods of surveying are very time-consuming, expensive, require a lot of human effort, and, thus, cannot be conducted frequently. A more efficient and cost-effective process is required to augment profilometer and traditional road-condition recognition systems. In this study, we propose deep-learning methods using smartphone data to devise a cost-effective and ad-hoc approach. Information from sensors on smartphones such as motion sensors and cameras are harnessed to detect road damage using deep-learning algorithms. In order to give heuristic and accurate information about the road damage, we used a cloud-based collaborative approach to fuse all the data and update a map frequently with these road-surface conditions. During the experiment, the deep-learning models achieved good prediction accuracy on our dataset, and the cloud-based fusion approach was able to group and merge the detections from different vehicles.
Post-mortem molecular profiling of three psychiatric disorders (2017)

We provide a comprehensive post-mortem transcriptome profile of three psychiatric disorders across three brain regions. We highlight a high-confidence set of independently validated genes differentially expressed between schizophrenia and control patients in the anterior cingulate cortex and integrate transcriptional changes with untargeted metabolite profiling.
Double-barrier resonant tunnelling diode three-state logic (1990)

Primary three-state logic circuits (inverters, OR gates and flip-flops) have been produced using double-barrier GaAs/ AlGaAs resonant tunnelling diodes. Circuit details, waveforms and three-state logic operations are described.
Double-blind Cross-over Study of Ketoprofen and Ibuprofen in Management of Rheumatoid Arthritis (1973)

A double-blind cross-over study of ketoprofen (Orudis) 150 mg daily and ibuprofen (Brufen) 1,200 mg daily was carried out in 35 outpatients with rheumatoid arthritis. Results suggest that analgesic and anti-inflammatory activity of ketoprofen is superior to that of ibuprofen. Significantly greater pain relief (P < 0.05) and reduction in joint circumference (P < 0.01) was obtained with ketoprofen than with ibuprofen. Side effects of the drugs were comparable and not serious.
Thermal conductivity measurements of epoxy systems at low temperature (2002)

We have developed a specific thermal conductivity measurement facility for solid materials at low temperature (LHe and LN2). At present, the Measurement of Thermal Conductivity of Insulators (MECTI) facility performs measurements on epoxy resin, as well as on bulk materials such as aluminum alloy and on insulators developed at Saclay. Thermal conductivity measurements on pre-impregnated fiber-glass epoxy composite are presented in the temperature range of 4.2 K to 14 K for different thicknesses in order to extract the thermal boundary resistance. We also present results obtained on four different bonding glues (Stycast 2850 FT, Poxycomet F, DP190, Eccobond 285) in the temperature range of 4.2 K to 10 K.
Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy (2013)

There was no evidence that ALC affected CIPN at 12 weeks; however, ALC significantly increased CIPN by 24 weeks. This is the first study to our knowledge showing that a nutritional supplement increased CIPN. Patients should be discouraged from using supplements without proven efficacy.
Précipitation des protéines par des acides gras : modélisation des équilibres entre phases (1997)

National audience
Women who present with female pattern hair loss tend to underestimate the severity of their hair loss (2004)

The results indicate that FPHL-affected women who seek treatment for FPHL do not overestimate the severity of the hair loss; in fact, they tend to underestimate. The present findings have implications for the treatment of FPHL.
Ordered Mesoporous Alumina-Supported Metal Oxides (2008)

The one-pot synthesis of alumina-supported metal oxides via self-assembly of a metal precursor and aluminum isopropoxide in the presence of triblock copolymer (as a structure directing agent) is described in detail for nickel oxide. The resulting mesoporous mixed metal oxides possess p6 mm hexagonal symmetry, well-developed mesoporosity, relatively high BET surface area, large pore widths, and crystalline pore walls. In comparison to pure alumina, nickel aluminum oxide samples exhibited larger mesopores and improved thermal stability. Also, long-range ordering of the aforementioned samples was observed for nickel molar percentages as high as 20%. The generality of the recipe used for the synthesis of mesoporous nickel aluminum oxide was demonstrated by preparation of other alumina-supported metal oxides such as MgO, CaO, TiO 2, and Cr 2O 3. This method represents an important step toward the facile and reproducible synthesis of ordered mesoporous alumina-supported materials for various applications where large and accessible pores with high loading of catalytically active metal oxides are needed.
Octree-based camera planning in virtual environments (2005)

When people navigate through virtual environments, they often manually control the camera, which may result in dizzy camera motions. In this paper, we introduce a new algorithm for camera planning in virtual environments, which will complete path planning, trajectory planning and orientation planning of virtual camera for the user with desired aesthetic qualities, while the user simply specifies the goal position. The path planning part of the algorithm is based on octree representation of the scene, associating with some ideas from visibility graph. It is more efficient and the resulting path is suitable for camera motion. We also describe an innovative approach for path smoothing and camera speed control in sharp turns, which strengthens the aesthetic effect with little overhead.
Formal modeling and verification of microprocessors (1995)

This paper presents a methodology for microprocessor verification that significantly reduces the learning curve for performing verification. The methodology is formalized in the HOL theorem-proving system. The paper includes a description of a large case study performed to evaluate the methodology. The novel aspects of this research include the use of abstract theories to formalize hardware models. Because our model is described using abstract theories, it provides a framework for both the specification and the verification. This framework reduces the number of ad hoc modeling decisions that must be made to complete the verification. Another unique aspect of our research is the use of hierarchical abstractions to reduce the number of difficult lemmas in completing the verification. Our formalism frees the user from directly reasoning about the difficult aspects of modeling the hierarchy, namely the temporal and data abstractions. We believe that our formalism, coupled with case studies and tools, allows microprocessor verification to be done by engineers with relatively little experience in microprocessor specification or logic. We are currently testing that hypothesis by using the methodology to teach graduate students formal microprocessor modeling.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Beam shaping of line generators based on high power diode lasers to achieve high intensity and uniformity levels (2008)

Beam shaping improvements of line generators based on high power diode lasers in combination with newly designed and produced high precision micro-optics lead to new applications such as hardening, metallization and annealing of different materials. Two aspects are mainly needed to be focused on for getting the best results and throughput in these applications. The first one is the overall power content along the narrow axis of the line, namely the peak intensity in combination with the beam shape. The second one is the intensity homogeneity along the long axis of the line. Herewith, a beam shaping concept that fulfils the desired requirements in a variable modality is presented. The concept consists of macro-lenses and newly designed micro-optics and results in a passively cooled high power diode laser emitting at 808nm. The laser has an output power of 1000W. The generated line has a length of 13mm and a width of <100μm at a remarkably large working distance of about 80mm. We attained an intensity distribution along the line length with a peak power density >80kW/cm<sup>2</sup> and uniformity >97%. To achieve such an extraordinary homogeneity level, several approaches based on cylindrical lens arrays were designed and tested. Methods to reduce inhomogeneities caused by diffraction effects and effects based on geometric optics are presented as well as their results. Additionally, the potential of this concept with regard to modularity, expandability and variability is reviewed. Finally, an application example - crystallisation of a thin film of a-Si on a glass substrate - is presented.
Improvement of an input waveform of a Neutral Point Type Step-down Converter (2006)

This paper presents one of the methods to improve a input current waveform of a neutral point type step-down converter circuit which we developed before. A neutral point type step-down converter circuit shares switching devices with half bridge inverter, and it is the circuit which can constitute an electronic ballast of a one converter method. A neutral point type step-down converter circuit has the problem that an input current does not flow through in the vicinity of zero cross point because It has some characteristic as step-down chopper circuit. This time, we solved this problem by adding an inductor to a circuit.
Crystal Characterization of Spherical Silicon Solar Cell by X-ray Diffraction (2006)

We have investigated the crystal quality of spherical Si solar cells by X-ray diffraction. A Si sphere with a diameter of 1 mm was fabricated by a dropping method. X-ray pole figure measurements confirmed that the Si sphere includes twin crystals. The spherical Si solar cells were fabricated using Si spheres. The spherical Si solar cells consisting of almost the same number of crystal grains exhibited various performance characteristics, because no clear correlation between the X-ray pole figure measurements indicating the grain number and the solar cell performance characteristics was confirmed. An X-ray rocking curve and a Dash etching method for the spherical Si solar cells indicated that the short-circuit current density and open-circuit voltage of the solar cells depend on the crystallinity of intragrains.
Highly nonlinear bismuth-oxide fiber for supercontinuum generation and femtosecond pulse compression (2005)

Highly nonlinear normally dispersive bismuth-oxide fiber shows promise for applications such as supercontinuum generation and femtosecond pulse compression in the telecommunications-wavelength range. To generate a wideband and flat supercontinuum spectrum, the balance between fiber nonlinearity and normal group velocity dispersion (GVD) is important. Highly nonlinear bismuth-oxide fiber exhibits a large nonlinearity due to the small effective area and nonlinear index of the host glass material. The fiber also has a relatively flat dispersion profile over a large wavelength range. Utilizing these features, we generate a smooth unstructured supercontinuum between 1200 and 1800 nm. This supercontinuum is passed through a grating pair, and pulses, originally of 150-fs length, are compressed to 25 fs.
On the complexity of minimum distance decoding of long linear codes (1999)

We suggest a decoding algorithm of q-ary linear codes, which we call supercode decoding. It ensures the error probability that approaches the error probability of minimum-distance decoding as the length of the code grows. For n/spl rarr//spl infin/ the algorithm has the maximum-likelihood performance. The asymptotic complexity of supercode decoding is exponentially smaller than the complexity of all other methods known. The algorithm develops the ideas of covering-set decoding and split syndrome decoding.
Near-UV narrow bandwidth optical gain in lattice-matched III–nitride waveguides (2018)

International audience
Graph Drawing by High-Dimensional Embedding (2004)

We present a novel approach to the aesthetic drawing of undirected graphs. The method has two phases: first embed the graph in a very high dimension and then project it into the 2-D plane using principal components analysis. Running time is linear in the graph size, and experiments we have carried out show the ability of the method to draw graphs of 10 5 nodes in few seconds. The new method appears to have several advantages over classical methods, including a significantly better running time, a useful inherent capability to exhibit the graph in various dimensions, and an effective means for interactive exploration of large graphs.
Use of Heterogenous and Monospecific Antisera for the Diagnosis of Bladder Cancer (1977)

A rabbit antibody to antigens present in urine from bladder cancer patients was prepared and used in conjunction with various monospecific antisera to detect urine components related to bladder cancer. All urine samples were centrifuged routinely, dialyzed and concentrated 10 times before assay by gel diffusion versus the various antisera. Urine was considered positive when it showed reactivity with 2 or more antibodies. This method of analysis resulted in the diagnosis of 64% of the bladder papillomas and 77% of the bladder cancers tested, compared to only a 7% falsely positive rate with normal urine. These data support the potential usefulness of an antiserum panel in the immunological diagnosis of bladder cancer in the general population and in high risk individuals.
Sub-linear root detection, and new hardness results, for sparse polynomials over finite fields (2013)

We present a deterministic 2O(t)qt-2/t-1 +o(1) algorithm to decide whether a univariate polynomial f, with exactly t monomial terms and degree <q, has a root in Fq. Our method is the first with complexity sub-linear in q when tis fixed. We also prove a structural property for the nonzero roots in Fq of any t-nomial: the nonzero roots always admit a partition into no more than 2√t-1(q-1)t-2/t-1 cosets of two subgroups S1 ⊆ S2 of F*q. This can be thought of as a finite field analogue of Descartes' Rule. A corollary of our results is the first deterministic sub-linear algorithm for detecting common degree one factors of k-tuples of t-nomials in Fq[x when k and t are fixed.
Regioselective Copper-Catalyzed Carboxylation of Allylboronates with Carbon Dioxide (2013)

In the presence of a Cu(I)/NHC catalyst, the reactions of allylboronic pinacol esters with CO2 (1 atm) are highly regioselective, giving exclusively the more substituted β,γ-unsaturated carboxylic acids in most cases. A diverse array of substituted carboxylic acids can be prepared via this method, including compounds featuring all-carbon quaternary centers.
Interactions between retinoids and TGF <i>β</i>s in mouse morphogenesis (1992)

Using immunocytochemical methods we describe the distribution of different TGF beta isoforms and the effects of excess retinoic acid on their expression during early mouse embryogenesis (8 1/2 - 10 1/2 days of development). In normal embryos at 9 days, intracellular TGF beta 1 is expressed most intensely in neuroepithelium and cardiac myocardium whereas extracellular TGF beta 1 is expressed in mesenchymal cells and in the endocardium of the heart. At later stages, intracellular TGF beta 1 becomes very restricted to the myocardium and to a limited number of head mesenchymal cells; extracellular TGF beta 1 continues to be expressed widely in cells of mesenchymal origin, particularly in head and trunk mesenchyme, and also in endocardium. TGF beta 2 is widely expressed at all stages investigated while TGF beta 3 is not expressed strongly in any tissue at the stages examined. Exposure of early neural plate stage embryos to retinoic acid caused reduced expression of TGF beta 1 and TGF beta 2 proteins but had no effect on TGF beta 3. Intracellular TGF beta 1 expression was reduced in all tissues except in the myocardium, while extracellular TGF beta 1 was specifically reduced in neuroepithelium and cranial neural crest cells at early stages. TGF beta 2 was reduced in all embryonic tissues. The down-regulation of intracellular TGF beta 1 was observed up to 48 hours after initial exposure to retinoic acid while some down-regulation of TGF beta 2 was still seen up to 60 hours after initial exposure.(ABSTRACT TRUNCATED AT 250 WORDS)
Applications of Machine Learning and High‐Dimensional Visualization in Cancer Detection, Diagnosis, and Management (2004)

Recent technical advances in combinatorial chemistry, genomics, and proteomics have made available large databases of biological and chemical information that have the potential to dramatically improve our understanding of cancer biology at the molecular level. Such an understanding of cancer biology could have a substantial impact on how we detect, diagnose, and manage cancer cases in the clinical setting. One of the biggest challenges facing clinical oncologists is how to extract clinically useful knowledge from the overwhelming amount of raw molecular data that are currently available. In this paper, we discuss how the exploratory data analysis techniques of machine learning and high-dimensional visualization can be applied to extract clinically useful knowledge from a heterogeneous assortment of molecular data. After an introductory overview of machine learning and visualization techniques, we describe two proprietary algorithms (PURS and RadViz) that we have found to be useful in the exploratory analysis of large biological data sets. We next illustrate, by way of three examples, the applicability of these techniques to cancer detection, diagnosis, and management using three very different types of molecular data. We first discuss the use of our exploratory analysis techniques on proteomic mass spectroscopy data for the detection of ovarian cancer. Next, we discuss the diagnostic use of these techniques on gene expression data to differentiate between squamous and adenocarcinoma of the lung. Finally, we illustrate the use of such techniques in selecting from a database of chemical compounds those most effective in managing patients with melanoma versus leukemia.
Synthesis of Spiroaminals and Spiroketals with Bimetallic Relay Catalysis (2013)

A novel tandem metal relay catalytic system was developed by combining gold-catalyzed cycloisomerization with an early transition-metal-catalyzed inverse-electron-demand hetero-Diels-Alder (IED-HDA) reaction. Various biologically important spiroaminals and spiroketals were obtained with very high efficiency under mild conditions.
An easily constructed, broad bandwidth ultrasonic probe for research purposes (1981)

For most purposes the requirements for an ideal ultrasonic probe are high efficiency, compact pulse shape and reproducibility in construction. For many practical applications the requirements of high efficiency (giving good signal-to-noise ratio) are paramount and the other ideals are sacrificed to a greater or lesser extent to achieve this. However, for research and for some practical applications like thickness gauging, it would often be convenient to work with less efficient probes provided that these were short-pulsed and could be manufactured in a reproducible manner. This paper describes one route to the construction of such a probe.