gebhart/patrepeval huggingface dataset:
An X-Band Paramp with 0.85 dB Noise Figure (uncooled) and 500 MHz Bandwidth (1972)

This paper describes the results of a development program which had two primary objectives: (1) the development of planar, passivated varactor chip diodes with a zero bias frequency cutoff of greater than 600 GHz, and (2) the employment of these chips in an uncooled, X-band Paramp System having a noise temperature of 60°K. GaAs Schottky barrier varactors with a cutoff frequency of 800 GHz have been used in a balanced diode type of parametric amplifier operating with a signal frequency at 7.6 GHz. The parameters of the overall amplifier operating at room temperature are: Gain of 15 dB, Bandwidth of 500 MHz, and an excess noise temperature of 62°K (a noise figure of 0.85 dB).
Size-controlled synthesis of quantum-sized EuS nanoparticles and tuning of their Faraday rotation peak (2005)

Size-controlled EuS nanoparticles were synthesized by the reaction of europium metal with thiourea as a sulfur source in liq. NH3, whose surface was confirmed to be modified with thiourea by FT-IR measurement, and the opto-magnetic properties (Faraday effect) of the EuS nanoparticles were investigated by using PMMA films containing the nanoparticles, showing that their Faraday rotation peaks were adjustable by control of their particle size.
Separating Translation from Protection in Address Spaces with Dynamic Remapping (2017)

It is time to reconsider memory protection. The emergence of large non-volatile main memories, scalable interconnects, and rack-scale computers running large numbers of small "micro services" creates significant challenges for memory protection based solely on MMU mechanisms. Central to this is a tension between protection and translation: optimizing for translation performance often comes with a cost in protection flexibility.
Erratum: Reflection and Refraction of Mechanical Waves at Solid—Liquid Boundaries (1963)

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Correlation of Naturally Occurring Infrasonics and Selected Human Behavior (1968)

An initial attempt is made to determine whether infrasonic waves generated by storms of distant origin affect local human behavior. Severe storm activity in North America was compared with the automobile accident rate and the rate for absenteeism among school children in the area of Chicago Illinois during the first 28 days of May 1967. The results suggest that a correlation may exist between the presence of infrasonic disturbances in the Chicago area and changes in selected human behavior. It is urged that more comprehensive studies of this nature be carried out.
Sensitivity to cis‐diamminedichloroplatinum in human cancer cells is related to expression of cyclin D1 but not C‐RAF‐1 protein (1996)

Although several oncogenes, including c-myc,ras and c-raf-1, have been implicated in cellular resistance to ionising radiation, there is less information relating oncogene expression to cis-diamminedochloroplatinum (CDDP) resistance. However, transfection of c-myc or v-H-ras and activation of protein kinase C (PKC), which contributes to the RAF-I, MAP kinase signal transduction pathway, can influence therapeutic response to CDDP. Activation of PKC increases CDDP sensitivity, whilst transfected c-myc or v-H-ras induce CDDP resistance. We have previously reported that human in vitro cell lines show different patterns of sensitivity to CDDP and 4 MeV X-irradiation. In these cells radiation sensitivity is related to high levels of expression of the c-raf-1 proto-oncogene. We thus predicted that cells sensitive to CDDP might show a different relationship to c-raf-1 expression. In addition, because cyclin D1 expression can be upregulated by the myc or ras oncogenes, we also chose to study putative relationships between cyclin D1 protein levels and intrinsic cellular sensitivity to CDDP and γ-irradiation. We report that in the 16 human cell lines which we have studied, high cyclin D1 expression is related to CDDP resistance but has no relationship with radiation responsiveness, whereas high c-raf-1 expression, although related to radiosensitivity has no relationship with CDDP responsiveness. © 1996 Wiley-Liss, Inc.
ChemInform Abstract: Synthesis of New Bifunctional Maleimide Compounds for the Preparation of Chemoimmunoconjugates. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Effect of Pelvic Muscle Exercise on Transient Incontinence During Pregnancy and After Birth (1999)

No AccessJournal of UrologyUrological Survey: Abstracts: Voiding Function and Dysfunction, and Female Urology1 Sep 1999Effect of Pelvic Muscle Exercise on Transient Incontinence During Pregnancy and After Birth C.M. Sampselle, J.M. Miller, B.L. Mims, J.O.L. Delancey, J.A. Ashton-Miller, and C.L. Antonakos C.M. SampselleC.M. Sampselle More articles by this author , J.M. MillerJ.M. Miller More articles by this author , B.L. MimsB.L. Mims More articles by this author , J.O.L. DelanceyJ.O.L. Delancey More articles by this author , J.A. Ashton-MillerJ.A. Ashton-Miller More articles by this author , and C.L. AntonakosC.L. Antonakos More articles by this author View All Author Informationhttps://doi.org/10.1097/00005392-199909010-00125AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Effect of Pelvic Muscle Exercise on Transient Incontinence During Pregnancy and After Birth." The Journal of Urology, 162(3 Part 1), p. 971 School of Nursing, Division of Health Promotion/Risk Reduction, Institute of Gerontology, Medical School and School of Engineering, University of Michigan, Ann Arbor, Michigan, and School of Nursing, Kent State University, Kent, Ohio© 1999 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 162Issue 3 Part 1September 1999Page: 971 Advertisement Copyright & Permissions© 1999 by American Urological Association, Inc.MetricsAuthor Information C.M. Sampselle More articles by this author J.M. Miller More articles by this author B.L. Mims More articles by this author J.O.L. Delancey More articles by this author J.A. Ashton-Miller More articles by this author C.L. Antonakos More articles by this author Expand All Advertisement PDF downloadLoading ...
An Assay for Small Scale Screening of Candidate β Cell Proliferative Factors Using Intact Islets (2013)

Current protocols for screening proliferative factors for β cells ex vivo are time-consuming, require cell lines or dissociated islets, and often entail expensive specialized screening equipment. Here we present an efficient and lower cost alternative that utilizes intact mouse islets for the initial screening of proliferative compounds and allows confirmation of β cell proliferation from the same islets. This protocol simplifies the process, saves money, and provides a way to identify β cell proliferative factors using equipment that is ubiquitous in most laboratories.
A set of 4 IC's in CMOS technology for a programmable hearing aid (2003)

A system of four integrated circuits developed for a programmable hearing aid is presented. The implementation of critical parts like the switched-capacitor filter bank, the low-noise preamplifiers, and the power supply are explained. The power is provided by a 1.3-V battery. The process used is the 3- mu m SACMOS from Faselec.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
‘A young slip of botany’: botanical networks, the South Atlantic, and Britain’s maritime worlds,<i>c.</i>1790–1810 (2016)

Abstract This article explores the relationship between science and empire, through the prism of British botanical engagement with the South Atlantic in the late eighteenth and early nineteenth centuries. It investigates the logistics of plant exchanges, as information, expertise, and specimens followed the maritime contours of the British empire. The discussion traces the nascent network-building undertaken by officials, residents, and visitors on St Helena and at the Cape of Good Hope, and the exchange of plant specimens with London and, crucially, with other places around the empire. The article suggests that such activities offer perspectives on wider patterns of interaction with an area located at the crossroads of Britain’s maritime empire. In time, the region forged its own botanical networks and created alternative axes of exchange, association, and movement.
Carrageenan from <i>Eucheuma striatum</i> (Schmitz) in Media for Fungal and Yeast Cultures (1981)

Fungi and yeasts were cultivated on media prepared from Eucheuma carrageenan. The cultures were found to compare well with those grown on agar media.
Antitumor activities of newly synthesized N4-acyl-1-beta-D-arabinofuranosylcytosine. (1976)

New derivatives of 1-beta-D-arabinofuranosylcytosine were synthesized and their antitumor activities were tested against mouse leukemia L1210. Among the 50 compounds investigated, a series of N4-acyl derivatives with long-chain saturated fatty acids were found to be highly active. The most active derivatives were N4-stearoly-1-beta-D-arabinofuranosylcytosine, which was administered in the form of suspension, and N4-behenoyl-1-beta-D-arabinofuranosylcytosine given in the form of solution. They were superior to the parent compound, 1-beta-D-arabinofuranosylcytosine, in that smaller dosages exhibited strong activities regardless of the treatment schedule, and they were also resistant to cytidine deaminase.
Methods in the treatment of obesity (2000)

L'obesitat es una malaltia molt estesa que limita l'activitat i escurca la vida, i que es pot definir com un emmagatzemament patologic de reserves de greix. Malgrat la difusio epidemica, no hi ha cap sistema plenament efectiu disponible per tractar-la. Les estrategies emprades per al tractament de l'obesitat s'han basat principalment en la l'imitacio de la ingesta i/o l'increment de la despesa energetica. EI metode mes emprat per l'imitar la ingesta energetica ha estat la utilitzacio de dietes hipocaloriques, pero l'efectivitat es limitada i es perd rapidament amb el temps. Malgrat aixo, la utilitzacio adequada de dietes hipocaloriques constitueix encara el principal procediment en la lluita contra el sobrepes. Tambe s'ha emprat el bloqueig de l'absorcio de nutrients mitjancant la inhibicio especifica d'enzims digestius. La cirurgia bariatrica es ara practicament l'unic metode prou efectiu per tractar els obesos morbids. S'ha utilitzat el condicionament conductista per mantenir els obesos allunyats del menjar, pero els resultats son sovint poc satisfactoris. No obstant aixo, la informacio adequada que reben els obesos sobre els principis elementals de la nutricio, aixi com la reeducacio nutricional son una eina que no s'ha de deixar de costat. L'exercici es Ia forma mes senzilla d'augmentar la despesa energetica i, tot i que aquest increment es sols transitori, potencia els efectes aprimadors de la restriccio dietetica. Hi ha un nombre considerable de farmacs que han estat emprats per al tractament de l'obesitat i encara n'hi ha mes que estan essent estudiats i desenvolupats. EI principal objectiu d'aquests farmacs es disminuir la gana a fi d'ajudar l'obes a reduir la quantitat de menjar, pero altres drogues tendeixen a incrementar la termogenesi, tot facilitant la utilitzacio de les reserves grasses; sovint ambdos efectes tenen lloc a l'hora. les drogues mes ampliament estudiades son les serotoninergiques, que actuen sobre el cervell, i els agents adrenergics que a
Synthesis and Anionic Ring-Opening Polymerization of a Novel Aromatic Cyclic Carbonate Having Binaphthyl Structure (1991)

Abstract A novel aromatic cyclic carbonate (3) having binaphthyl structure was prepared by the reaction of 2,2′-binaphthol with 4-nitrophenyl chloroformate in the presence of a tert-amine. 3 polymerized very efficiently with potassium tert-butoxide at 20 °C to give corresponding linear polycarbonate with 12800 (/ 1.34) in 94% yield.
Anionic copolymerization of styrene and 1,1‐diphenylethylene (1966)

Abstract Kinetics of anionic copolymerization of styrene (S) and 1,1‐diphenylethylene (D) were investigated in THF. The rate constant of addition of D to living polystyrene was found to be k 1,2 ± = 250 l./mole‐sec. for , Na + ion‐pair, and that for the free , Na + ion is k 1,2− ∼400,000 l./mole‐sec. Both values refer to 25°C. The addition of styrene to D − , Na + was found to be reversible: magnified image and k 2,1 was determined by three different methods to be ∼0.5–0.7 l./mole‐sec. Studies performed in a stirred‐flow reactor led to k ‐ 21 = 13 sec. −1 and K 21 ∼ 5 × 10 −2 l./mole. An alternating copolymer is obtained in the presence of a large excess of 1,1‐diphenylethylene.
Towards a garment OS (2014)

Wearable devices and the development of smart garments emerged into a significant research domain over the last decades. Despite the increasing commercial interest, however, smart garments are almost exclusively developed in academia and the developed systems do not exceed a prototypical level. We argue that the main reason why smart garments cannot be produced on commercially relevant scale today is that they each focus on a specific use case. There is no tool support for application developers and no defined APIs within the software and hardware stack that allows developing useful smart garment applications. In this paper we present our work towards Garment OS, a layered software stack that encapsulates different levels of abstraction. We highlight the design of that system which is based on open web protocols. We present an evaluation with software engineers and derive directions for future work.
Novelty Detection-Based Internal Fingerprint Segmentation in Optical Coherence Tomography Images (2014)

Biometric fingerprint scanners scan the external skin features onto a 2-D image. The performance of the automatic fingerprint identification system suffers if the finger skin is wet, worn out, fake fingerprint is used et cetera. In this paper, we present an automatic segmentation of the papillary layer method, in 3-D swept source optical coherence tomography (SS-OCT) images. The papillary contour represents the internal fingerprint, which does not suffer external skin problems. The slices composing the 3-D image are filtered by the regularized Perona and Malik partial differential equations filter to minimize the effect of speckle noise. Then the corneum stratum is detected, which in turn leads to the extraction of the epidermis using prior knowledge of the epidermis depth. The epidermis is used as the target of the novelty detection that is applied to the image slices. The contour of the papillary layer is segmented as the boundary between the target and rejection classes resulting from novelty detection. The papillary contours are consistent with those segmented manually, with the modified Williams index above 0.9400 on average. The 3-D papillary contour represents an internal fingerprint.
Compartmentalized Control of Skin Immunity by Resident Commensals (2012)

Intestinal commensal bacteria induce protective and regulatory responses that maintain host-microbial mutualism. However, the contribution of tissue-resident commensals to immunity and inflammation at other barrier sites has not been addressed. We found that in mice, the skin microbiota have an autonomous role in controlling the local inflammatory milieu and tuning resident T lymphocyte function. Protective immunity to a cutaneous pathogen was found to be critically dependent on the skin microbiota but not the gut microbiota. Furthermore, skin commensals tuned the function of local T cells in a manner dependent on signaling downstream of the interleukin-1 receptor. These findings underscore the importance of the microbiota as a distinctive feature of tissue compartmentalization, and provide insight into mechanisms of immune system regulation by resident commensal niches in health and disease.
The genesis of arrhythmias during myocardial ischemia. Dissociation between changes in cyclic adenosine monophosphate and electrical instability in the rat. (1985)

It has been proposed that increases in tissue cyclic adenosine monophosphate during ischemia may be responsible for the induction of arrhythmias that occur during the early minutes of ischemia. We have tested this hypothesis using the isolated perfused rat heart with coronary artery occlusion for 30 minutes. In control hearts, after a transient small rise, cyclic adenosine monophosphate content remained close to its preischemic value (3.0 +/- 0.1 nM/g dry weight) throughout the period of occlusion. Eight percent (1/12) of the hearts fibrillated. Ninety-two percent (11/12) of the hearts exhibited ventricular tachycardia, and the mean total number of premature ventricular complexes was 528 +/- 121. Inclusion of epinephrine (1.0 microM) in the perfusion fluid elevated cyclic adenosine monophosphate prior to coronary occlusion (to 10.7 +/- 0.6 nM/g dry weight) and also throughout the ischemic period. It also increased arrhythmias such that 83% (20/24) of hearts fibrillated, 100% exhibited ventricular tachycardia, and the mean number of premature ventricular complexes increased to 747 +/- 86. Inclusion of forskolin (0.2 microM), which stimulates adenyl cyclase independently of the beta-receptor, increased cyclic adenosine monophosphate content to a greater extent than epinephrine, to 14.1 +/- 0.9 nM/g dry weight before the onset of ischemia and to 8.2 +/- 0.4 nM/g dry weight after 30 minutes of ischemia. Despite the large increase in cyclic adenosine monophosphate, there was no increase in rhythm disturbances which were less than those seen in controls.(ABSTRACT TRUNCATED AT 250 WORDS)
Identification and characterization of an endogenous P2X<sub>7</sub> (P2Z) receptor in CHO‐K1 cells (1998)

CHO-K1 cells were examined for their cellular responses to the P2 receptor agonist, 2'- and 3'-O-(4-benzoylbenzoyl)-ATP (DbATP), and for the presence of mRNA for P2X receptors. Reverse transcriptase-polymerase chain reactions, using primers directed against the rat P2X subunits, detected the presence of P2X7 but not P2X1-P2X6 subunits. DbATP (EC50 approximately equal to 100 microM) evoked non-desensitizing inward currents which reversed at approximately equal to 0 mV, suggesting activation of a non-selective cation channel. ATP also evoked inward currents but was less potent than DbATP. DbATP also stimulated the accumulation of 45calcium (45Ca2+) and the DNA binding dye, YO-PRO-1, in CHO-KI cells. Both responses were inhibited by NaCl and MgCl2. In 280 mM sucrose buffer, 45Ca2+ accumulation was measurable within 10-20 s of agonist addition, whereas YO-PRO-1 accumulation was only detectable after 8 min. ATP and ATPgammaS were also agonists but were less potent than DbATP, while UTP, 2-methylthio ATP, ADP and (alphabeta)methylene ATP were inactive at concentrations up to 100 microM. DbATP increased lactate dehydrogenase release from CHO-K1 cells, suggesting cell lysis, although this effect was only pronounced after 60-90 min. These data suggest that CHO-K1 cells express an endogenous P2X7 receptor which can be activated by DbATP to cause a rapid inward current and accumulation of 45Ca2+. Prolonged receptor activation results in a delayed, increased permeability to larger molecules such as YO-PRO-1 and ultimately leads to cell lysis. Importantly, the presence of an endogenous P2X7 receptor should be considered when these cells are used to study recombinant P2X receptors.
Tunable Microwave Filters using YIG Grown by Liquid Phase Epitaxy (1974)

Original work is described on the application of refinements in Liquid Phase Epitaxy (LPE) of yttrium iron garnet (YIG) to the fabrication of tunable microwave filters. The advantages in cost and performance of this approach over the conventional YIG sphere technology are discussed. The developments in the LPE of YIG and the reactor used are described. The viability of LPE-YIG filters is demonstrated by linewidth and external Q (Qe) measurements on bandstop and bandpass filters. Techniques for resonator-resonator coupling are described. The design parameters and measured performance of multi-pole bandpass filters are compared and shown to be consistent.
A new  -interferon-inducible promoter and splice variants of an anti-angiogenic human tRNA synthetase (2004)

Two forms of human tryptophanyl-tRNA synthetase (TrpRS) are produced in vivo through alternative mRNA splicing. The two forms, full-length TrpRS and mini TrpRS, are catalytically active, but are distinguished by the striking anti-proliferative and anti-angiogenic activity specific to mini TrpRS. Here we describe two new splice variants of human TrpRS mRNA. Their production was strongly regulated by gamma-interferon (IFN-gamma), an anti-proliferative cytokine known to stimulate the expression of other anti-angiogenic factors. A new IFN-gamma-sensitive promoter was demonstrated to drive production of these splice variants. In human endothelial cells, both the newly discovered and a previously reported promoter were shown to respond specifically to IFN-gamma and not to other cytokines such as tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-4 or erythropoietin. In addition, both promoters were stimulated by the 'downstream' interferon regulatory factor 1 that, in turn, is known to be regulated by the 'upstream' signal transducer and activator of transcription 1alpha subunit. Thus, the tandem promoters provide a dual system to regulate expression and alternative splicing of human TrpRS in vivo.
Magnetic resonance pharmacoangiography to detect and predict chemotherapy delivery to solid tumors. (2001)

Detection and prediction of drug delivery to the tumor interstitium are of critical importance in cancer chemotherapy. Prediction of drug delivery derived from standard pharmacokinetic models is frequently inadequate because of the complex nature of tumor blood flow and the microenvironment. Although drug concentrations can be directly sampled with microdialysis or in biopsy samples, we currently lack methods capable of detecting and/or predicting drug delivery to tumors noninvasively. In this study, we describe a novel magnetic resonance (MR) technique to directly detect the drug, and we present the correlation between delivery of drug and the delivery of MR contrast agents to the tumor. Experiments were performed with tumor xenografts in severe combined immunodeficient mice. Three-dimensional maps of the drug distribution within the tumors were obtained with 13C spectroscopic MR imaging with a spatial resolution of 2 x 2 x 2 mm, using signals of the 13C-labeled anticancer agent phenylacetate. Three-dimensional maps of uptake of gadolinium-diethylenetriaminepentaacetic acid (GdDTPA) contrast agent were obtained for the same tumors using dynamic MR imaging. Experimental data were analyzed for correlation between delivery of the drug and the contrast. Histological analysis was performed for excised tumors. Experimental data demonstrated a significant spatial correlation (r = 0.59 with P < 0.001) between the parameter representing delivery of the contrast to tumor interstitium, determined from the kinetic curves of GdDTPA, and integral tissue drug concentrations for two different tumor models. The method is designed to probe extravasation of the drug molecules from the bloodstream into the tumor interstitium. Although therapeutic efficiency of the drug will also depend upon drug retention in the tumor and the ability of the molecules to cross cellular membranes, inefficient drug transfer from plasma to tissue can be a major impediment in achieving effective tumor chemotherapy. The results of this study demonstrate that the uptake kinetics of a low molecular weight MR contrast agent can be used to predict delivery of drug molecules of similar size to the interstitium of solid tumors.