gebhart/patrepeval huggingface dataset:
Protective immunity induced by B7/CD28-costimulated γ δ T cells to the EL-4 lymphoma in allogenic athymic mice (1995)

We previously reported that the murine EL-4 lymphoma (H-2b) transduced with a retrovirus containing the murine B7-1 gene (B7+ EL-4) grew transiently for several weeks and subsequently regressed in allogenic BALB/c (nu/nu) athymic mice (H-2d). We now show that, in contrast, B7+ EL-4 cells grow progressively in several combined immunodeficiency mice, including SCID and NIH III mice, which lack T cells expressing either TCR-alpha beta or -gamma delta. Furthermore, depletion of gamma delta T cells with a specific mAb made possible the progressive growth of B7+ EL-4 cells in 90% of athymic mice while depletion of alpha beta T cells allowed tumor growth in 50% of these mice. Immunization of athymic mice with B7+ EL-4 cells prevented the outgrowth of wild-type B7- EL-4 cells. This protective immunity was abrogated by in vivo treatment with an anti-TCR-gamma delta mAb, further indicating that gamma delta T cells play an important role in tumor rejection by athymic mice. A gamma delta T cell line, Tc1, was established from B7+ EL-4-immunized athymic mice by repeated restimulation in vitro with irradiated B7+ EL-4 cells. When tested against a broad spectrum of target cells, Tc1 lysed several murine lymphoma lines, but did not lyse other tumor lines, suggesting that the Ag recognized by Tc1 has a limited distribution. Our data demonstrate that gamma delta T cells, and, to a less extent, extrathymic alpha beta T cells, mediate an immune response against B7+ EL-4 cells in allogeneic athymic mice.
An 8-bit/s speech coder based on conjugate structure CELP (1993)

A high-quality 8-bit/s speech coder based on CS:CELP (conjugate structure code excited linear prediction) with 10 ms frame length is presented. To provide high quality in both error-free and error conditions, it uses four schemes: LSP (line spectrum pair) quantization using interframe correlation, preselection of codebook search, a conjugate structure, and backward adaptation of the VQ (vector quantization) gain. LSP parameters are quantized by multistage VQ with MA prediction. The preselection of the codebook reduces computational complexity and improves robustness. The CS improves the ability to handle random bit errors and reduces memory requirements. The backward adaptation of the VQ gain provides high quality and robustness without having to transmit input speech power information. Subjective testing indicates that the quality of the proposed coder is equivalent to that of the 32 kbit/s ADPCM (adaptive differential pulse code modulation) under error-free conditions. It is also found that the proposed coder is robust against random bit errors.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Polymer-Based Scale Inhibitors for Seawater Injection Operations in High-Salinity Formation Water Reservoirs (2015)

Abstract Water flooding using seawater is a major oil filed operation implemented in different carbonate and sandstone reservoirs to maintain reservoir pressure and enhance oil recovery. However, due to the high sulfate content in the injected seawater, significant calcium, barium and strontium sulfate scale deposition can occur and cause severe formation damage. Typically, scale inhibitors are applied in the field to prevent the formation of calcium sulfate scale where they act either as chelating agents to form a soluble complex, as threshold inhibitors, which block the development of the supercritical nuclei or as retarders of the growth of the calcium sulfate crystals. The objective of this study is to evaluate the effectiveness of different types of scale inhibitors to prevent the formation of calcium sulfate scale during the injection of seawater into high-salinity bearing carbonate reservoirs. Jar testing and SoftPitzerTM software were used to investigate the calcium sulfate precipitation due to the mixing of high calcium-content (37,000 mg/L) formation water and high sulfate-content (4,000 mg/L) seawater. This investigation was conducted on different mixtures of formation water and seawater at reservoir temperature of 155°F. Different types of scale inhibitors were tested to prevent the scaling of calcium sulfate in mixtures of seawater and formation water. The compatibility of these scale inhibitors with calcium ions present in formation water and also their effectiveness in preventing CaSO4 scaling were investigated using bottle testing. In addition, coreflood experiments were conducted to determine the adsorption behavior of these inhibitors in carbonate rocks. Results showed that the application of two scale inhibitors (Acrylic homopolymer-based) can successfully mitigate calcium sulfate scale formation in seawater/formation water mixtures up to 155°F. Each one of these two scale inhibitors has its own effective minimum inhibition concentration (MIC). In addition to these results, the paper provides insights into the adsorption behavior of these inhibitors in carbonate rocks and how this affects their performance.
Real-Time Rendering of Soft Shadows (2019)

This thesis presents a method to render real time soft shadows efficiently on modern GPUs using a combination of low discrepancy sampling sequences and spatiotemporal convolution. A theoretical foundation of shadows and shadow rendering will be presented together with common algorithms used for shadow rendering and light space convolution. The method presented is a reasonable candidate for games and other interactive applications aiming to provide visually pleasing soft shadows.
Protocol for Dynamic Component-Property Attestation in Trusted Computing (2010)

This paper gives a way of implementing a high-speed and reliable data conversion between UART and WLAN. After introducing the overview of our system, this paper shows the hardware structure and firmware design in brief. Then we analyze the bottleneck of the data conversion and give a way of how to improve and optimize the firmware to complete a high speed and reliable data conversion in detail. We use DMA mechanism and data flow control to ensure the speed and reliability of data conversion. We add traffic self-adaptation feature to make the data conversion adapted to different data rate. We also show how to reduce the influence caused by the instability of wireless connection. Complete performance test will be taken at the end of this paper.
An Overview of Formation Damage Mechanisms Causing a Reduction in the Productivity and Injectivity of Oil and Gas Producing Formations (2002)

Introduction Formation damage is a hot topic these days-with justifiable reason, as more operating companies move to the exploitation of more and more challenging oil and gas reservoirs in tighter, deeper, and more depleted conditions. Disappointing production or injection results from an oil or gas well can be related to a number of factors which may be difficult to diagnose. Some of these may center about poor inherent natural reservoir quality characteristics, others about mechanical considerations surrounding the condition and type of the wellbore obtained, and still others under the nebulous catch-all of "formation damage" which often (and sometimes unjustly) absorbs the majority of the blame for the poor results of many projects. Formation damage in oil and gas wells is difficult to quantify in many cases. This is due to the inability of the reservoir engineer to retrieve exact samples and conduct detailed measurements on the area of interest, usually represented by a volume of rock surrounding the wellbore which is generally several thousand meters below the surface of the earth. However, ongoing research over the years has allowed the development of a variety of techniques allowing the use of the available information to obtain a much better indication f the type and degree of damage which different reservoirs may be sensitive to, thereby adjusting operating practices to attempt to minimize or reduce these permeability reducing factors. This data would include information such as production and pressure data, pressure transient data, log analysis, fluid and PVT data and core, cuttings, and special core analysis data. The subject of this brief article is to provide a synopsis of some of the types of formation damage which commonly present themselves as problems for many oil and gas producing projects, and review some of the associated technology being used to overcome these problems. How Much of a Concern is Formation Damage? A technical definition of formation damage would be "any process that causes a reduction in the natural inherent productivity of an oil or gas producing formation, or a reduction in the injectivity of a water or gas injection well." Although the drilling process often bears the brunt of the blame, formation damage can occur at any time during the life of a well including completion, production, stimulation, kill, or workover operations. Often the problem is ignored due to a combination of ignorance and apathy with the common rationale that "We don't care about formation damage in this reservoir-we can always fracture through it." Surprisingly, this pretense may make sense in certain situations, particularly when the formation is of such low inherent quality that it is obvious the flow area and driving differential pressure available for production present in a normal cased and perforated or open hole completion are insufficient to sustain economic production rates, even with a totally "non damaged" well.
Replication-Competent Herpes Simplex Virus Vectors for Cancer Therapy (2001)

Research Articles| October 01 2008 Geographical Pathology of Fatal Lung Embolism Subject Area: Further Areas , Oncology , Pathology and Cell Biology W. Sandritter; W. Sandritter Department of Pathology, Justus Liebig University, Giessen Search for other works by this author on: This Site PubMed Google Scholar H. Felix H. Felix Department of Pathology, Justus Liebig University, Giessen Search for other works by this author on: This Site PubMed Google Scholar Pathologia et Microbiologia (1967) 30 (5): 742–746. https://doi.org/10.1159/000161720 Article history Published Online: October 01 2008 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation W. Sandritter, H. Felix; Geographical Pathology of Fatal Lung Embolism. Pathologia et Microbiologia 1 May 1967; 30 (5): 742–746. https://doi.org/10.1159/000161720 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPathobiology Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 1967Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Design and assembly of a telecentric zoom lens for the Cygnus x-ray source (2012)

Cygnus is a high-energy radiographic x-ray source. The rod-pinch x-ray diode produces a point source measuring 1 mm diameter. The target object is placed 1.5 m from the x-ray source, with a large LYSO scintillator at 2.4 m. Differentsized objects are imploded within a containment vessel. A large pellicle deflects the scintillator light out of the x-ray path into an 11-element zoom lens coupled to a CCD camera. The zoom lens and CCD must be as close as possible to the scintillator to maximize light collection. A telecentric lens design minimizes image blur from a volume source. To maximize the resolution of test objects of different sizes, the scintillator and zoom lens can be translated along the x-ray axis. Zoom lens magnifications are changed when different-sized scintillators and recording cameras are used (50 or 62 mm square format). The LYSO scintillator measures 200 × 200 mm and is 5 mm thick. The scintillator produces blue light peaking at 435 nm, so special lens materials are required. By swapping out one lens element and allowing all lenses to move, the zoom lens can also use a CsI(Tl) scintillator that produces green light centered at 550 nm. All lenses are coated with anti-reflective coating for both wavelength bands. Two sets of doublets, the stop, and the CCD camera move during zoom operations. One doublet has XY compensation. The first three lenses use fused silica for radiation damage control. The 60 lb of glass inside the 340 lb mechanical structure is oriented vertically.
A frequency domain time-dependent adaptive filter for interference rejection (2003)

The authors examine a type of adaptive filter called a time-dependent adaptive filter (TDAF). A TDAF can effectively deal with the cyclostationary nature of communication signals by changing periodically. It achieves a smaller mean-square error than conventional filter for cyclostationary signals. A frequency-domain TDAF is investigated, and it is shown that it is especially effective for interference rejection applications. Simulation results are presented, showing how cochannel QPSK signals can be separated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Ozone and Pulmonary Innate Immunity (2007)

Ambient ozone (O(3)) is a commonly encountered environmental air pollutant with considerable impact on public health. Many other inhaled environmental toxicants can substantially affect pulmonary immune responses. Therefore, it is of considerable interest to better understand the complex interaction between environmental airway irritants and immunologically based human disease. The innate immune system represents the first line of defense against microbial pathogens. Intact innate immunity requires maintenance of an intact barrier to interface with the external environment, effective phagocytosis of microbial pathogens, and precise detection of pathogen-associated molecular patterns. We use ambient O(3) as a model to highlight the importance of understanding the role of exposure to ubiquitous air toxins and regulation of basic immune function. Inhalation of O(3) is associated with impaired antibacterial host defense, in part related to disruption of epithelial barrier and effective phagocytosis of pathogens. The functional response to ambient O(3) seems to be dependent on many components of the innate immune signaling. In this article, we review the complex interaction between inhalation of O(3) and pulmonary innate immunity.
Techniques for channel estimation, DC-offset compensation, and link quality control in Bluetooth system (2000)

This paper presents a channel estimation and a DC-offset estimation techniques, and two error control methods in a short-ranged Bluetooth system. Each of the Bluetooth devices in the connection state knows the access codes used in the ad-hoc networks, which is utilized as a reference signal for the parameter estimation. Also, the access correlation output can help the error correction schemes of the Bluetooth networks because the correlation output reflects the radio channel environments. The proposed estimators can be implemented without degradation of frame and spectral efficiency thanks to using the access code specified for the Bluetooth system.
Modeling and layout optimization of VLSI devices and interconnects in deep submicron design (2002)

This paper presents an overview of recent advances on modeling and layout optimization of devices and interconnects for high-performance VLSI circuit design under the deep submicron technology. First, we review a number of interconnect and driver/gate delay models, which are most useful to guide the layout optimization. Then, we summarize the available performance optimization techniques for VLSI device and interconnect layout, including driver and transistor sizing, transistor ordering, interconnect topology optimization, optimal wire sizing, optimal buffer placement, and simultaneous topology construction, buffer insertion, buffer and wire sizing. The efficiency and impact of these techniques will be discussed in the tutorial.
Psychosocial outcomes and health status of adults who have had juvenile rheumatoid arthritis. A controlled, population‐based study (1997)

Adults who have had JRA during childhood experience long-term physical and psychosocial impairment.
像黑洞一样的“超级黑”材料 (2014)

日前,科学家研发出一种＂超级黑＂材料,这种材料堪称目前＂最黑＂的材料,仅反射0.035%的光,达到了肉眼根本无法分辨的程度,黑得就像出现了一个黑洞。据英国《独立报》网站报道,这种＂超级黑＂涂层材料被命名为＂Vantablack＂（梵塔黑）。
Thermal behavior of complex, tunnel-structure manganese oxides (1989)

rhBMP-2 can suppress the proliferation of SHG44 gliomas and induce its apoptosisN:
Les noms de cours d'eau formés par découpage d'un nom de cours d'eau ou de lieu (1927)

info:eu-repo/semantics/published
Mango modulates body fat and plasma glucose and lipids in mice fed a high-fat diet (2011)

Consumption of fruits and vegetables has been investigated for their role in the prevention of many chronic conditions. Among the fruits, mango provides numerous bioactive compounds such as carotenoids, vitamin C and phenolic compounds, which have been shown to have antioxidant and anti-inflammatory properties. The present study examined the effects of dietary supplementation of freeze-dried mango pulp, in comparison with the hypolipidaemic drug, fenofibrate, and the hypoglycaemic drug, rosiglitazone, in reducing adiposity and alterations in glucose metabolism and lipid profile in mice fed a high-fat (HF) diet. Male C57BL/6J mice were randomly divided into six treatment groups (eight to nine/group): control (10 % energy from fat); HF (60 % energy from fat); HF+1 or 10 % freeze-dried mango (w/w); HF+fenofibrate (500 mg/kg diet); HF+rosiglitazone (50 mg/kg diet). After 8 weeks of treatment, mice receiving the HF diet had a higher percentage body fat (P = 0·0205) and epididymal fat mass (P = 0·0037) compared with the other treatment groups. Both doses of freeze-dried mango, similar to fenofibrate and rosiglitazone, prevented the increase in epididymal fat mass and the percentage of body fat. Freeze-dried mango supplementation at the 1 % dose improved glucose tolerance as shown by approximately 35 % lower blood glucose area under the curve compared with the HF group. Moreover, freeze-dried mango lowered insulin resistance, as indicated by the homeostasis model assessment of insulin resistance, to a similar extent as rosiglitazone and modulated NEFA. The present findings demonstrate that incorporation of freeze-dried mango in the diet of mice improved glucose tolerance and lipid profile and reduced adiposity associated with a HF diet.
Response to the ODMG-93 commentary written by Dr. Won Kim of UniSQL, Inc. (1994)

In the March 1994 issue of the ACM SIGMOD Record, Dr. Won Kim of UniSQL and the SIGMOD Chairperson published “Observations on the ODMG-93 Proposal for Object-Oriented Database Language” (Volume 23, Number 1). This commentary contained some useful technical contributions. We thank Dr. Kim for that. Nevertheless, it also contained a number of inaccuracies and misleading statements that we, the ODMG, would like to set straight.
The Extended Invariant Factor Algorithm with Application to the Forney Analysis of Convolutional Codes (2005)

In his celebrated paper on the algebraic structure of ConvoJutional codes, Forney 111 showed that by using the invariant-factor theorem, one can transform an arbitrary polynomial generator matrix for an (n, k ) convolutional code C into a basic (and ultimately a minimal) generator matrix for C.He also showed how to find a polynomial inverse for a basic generator matrix for C, and a basic generator matrix for the dual code CL.In this paper, we will discuss efficient ways to do aJ1 these things.Our main tool is the "entended invariant factor algorithm," which we introduce here.
Lpp34, a Novel Putative Lipoprotein from<i>Mycobacterium avium</i>subsp.<i>paratuberculosis</i> (2006)

A Mycobacterium avium subsp. paratuberculosis expression library in lambda ZAP was screened with immunized mice sera. One clone was selected, sequenced and further characterized. The sequence analysis of the hypothetical open-reading frame (ORF) predicts a protein of 20.8 kDa with a probable signal sequence compatible with Cys-acylation at Cys24, characteristic of lipoproteins. In consequence, the protein was termed Lpp34. Recombinant expression of Lpp34 was achieved by cloning the lpp34 gene into the histidine-tag expression vector pRSET-A. Western blot analysis showed a protein band with a molecular weight of 34 kDa. The native protein was localized in the membrane fraction of M. avium subsp. paratuberculosis and extracted in the detergent phase of Triton X-114. Southern blot and polymerase chain reaction showed that the gene is absent from all the non-M. avium complex mycobacterial genomes tested. Humoral reactivity using bovine sera demonstrated that this protein is widely recognized by both the infected and non-infected animals. This could partly be due to the conserved sequence in close-related environmental bacteria such as M. avium subsp. avium and to the presence of a conserved epitope in other bacteria such as Escherichia coli. In conclusion, these findings show that Lpp34 is a membrane protein and a putative lipoprotein present in M. avium complex mycobacteria and absent in the M. tuberculosis complex.
Mobility edge in hydrogenated amorphous carbon (2006)

Optical and electronic properties of plasma enhanced chemical vapor deposited diamondlike amorphous carbon (a-C:H and a-C1−xSix:H) films were studied by photothermal deflection spectroscopy and the spectral photocurrent method. Two different regimes of photoconductivity in the diamondlike carbon films have been detected. The carrier mobility due to the σ-σ* bands is found to be 1–2 orders of magnitude higher than that due to the π-π* transitions. The σ-σ* mobility edge of diamondlike hydrogenated amorphous carbon is equal to 5.3±0.1eV and appears to be closely correlated with the band gap of diamond. We have also shown that the mobility edge in diamondlike amorphous carbon is not associated with its band gap. The optical band gap of diamondlike amorphous carbon films depends on the sp2 phase content as already reported by Robertson [Phys. Rev. B 53, 16302 (1996)]. However, the mobility edge is not influenced by either the Si doping level, the film thickness, or the ion impact energy during deposition.