gebhart/patrepeval huggingface dataset:
Stable monomeric complexes of molybdenum(III) and tungsten(III) (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStable monomeric complexes of molybdenum(III) and tungsten(III)M. Millar, S. Lincoln, and S. A. KochCite this: J. Am. Chem. Soc. 1982, 104, 1, 288–289Publication Date (Print):January 1, 1982Publication History Published online1 May 2002Published inissue 1 January 1982https://pubs.acs.org/doi/10.1021/ja00365a052https://doi.org/10.1021/ja00365a052research-articleACS PublicationsRequest reuse permissionsArticle Views428Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Experimental study of substrate temperature (1989)

Substrate temperature is one of the most important processing parameters for optical coating deposition. The distribution of substrate temperature during deposition has been measured and calculated. Two kinds of heating method have been compared. The experiments show that the use of halogen lamps in a front surface heating system can achieve better uniformity of temperature distribution and diminish the influence of the evaporating source. The experiments provide some very useful production processing parameters.
Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway (1998)

The signaling pathways that couple tumor necrosis factor-alpha (TNFalpha) receptors to functional, especially inflammatory, responses have remained elusive. We report here that TNFalpha induces endothelial cell activation, as measured by the expression of adhesion protein E-selectin and vascular adhesion molecule-1, through the sphingosine kinase (SKase) signaling pathway. Treatment of human umbilical vein endothelial cells with TNFalpha resulted in a rapid SKase activation and sphingosine 1-phosphate (S1P) generation. S1P, but not ceramide or sphingosine, was a potent dose-dependent stimulator of adhesion protein expression. S1P was able to mimic the effect of TNFalpha on endothelial cells leading to extracellular signal-regulated kinases and NF-kappaB activation, whereas ceramide or sphingosine was not. Furthermore, N, N-dimethylsphingosine, an inhibitor of SKase, profoundly inhibited TNFalpha-induced extracellular signal-regulated kinases and NF-kappaB activation and adhesion protein expression. Thus we demonstrate that the SKase pathway through the generation of S1P is critically involved in mediating TNFalpha-induced endothelial cell activation.
Properties of Oxynitride Glasses in the Ln-Si-Al-O-N Systems (Ln=Rare-Earth) (1994)

The properties of rare-earth-containing oxynitride glasses in the Ln-Si-Al-O-N systems (Ln=Dy, Er, Gd, La, Nd, Sm, Y, Yb) were investigated and the following results were obtained.(1) The glass transition temperature and the softening temperature in these glasses are in a range of 915-950°C and 960-1020°C, respectively.(2) The correlation between the glass transition and softening temperatures of glasses and the radius of rare-earth ion is weak in these oxynitride glasses.(3) The oxidation behaviors of the Ln-Si-Al-O-N glasses were analyzed by assuming that the weight change was proportional to the n-th power of oxidation time, and it was found that the oxidation exponent, n, tends to decrease and that the oxidation resistance tends to increase as the radius of rare-eath ion decreases.(4) The Yb-Si-Al-O-N glass has the best oxidation resistance in the Ln-Si-Al-O-N glasses obtained in this work.(5) In the oxidation process of the Yb-Si-Al-O-N glass, n equals 1 at the initial stage (interface reaction controlled oxidation), 1/2 at the middle stage (diffusion controlled oxidation) and 1/6 at the final stage of oxidation. In the stage of n=1/6, the oxidation rate is decelerated than that of the parabolic law, because many crystals grow from the interface to the inner parts of glass and the amount of glassy phase at the vicinity of interface are contracted during oxidation.
Identification of Critical Residues in the Active Site of Porcine Membrane-Bound Aminopeptidase P (2000)

The membrane-bound form of mammalian aminopeptidase P (AP-P; EC 3.4. 11.9) is a mono-zinc-containing enzyme that lacks any of the typical metal binding motifs found in other zinc metalloproteases. To identify residues involved in metal binding and catalysis, sequence and structural information was used to align the sequence of porcine membrane-bound AP-P with other members of the peptidase clan MG, including Escherichia coli AP-P and methionyl aminopeptidases. Residues predicted to be critical for activity were mutated and the resultant proteins were expressed in COS-1 cells. Immunoelectrophoretic blot analysis was used to compare the levels of expression of the mutant proteins, and their ability to hydrolyze bradykinin and Gly-Pro-hydroxyPro was assessed. Asp449, Asp460, His523, Glu554, and Glu568 are predicted to serve as metal ion ligands in the active site, and mutagenesis of these residues resulted in fully glycosylated proteins that were catalytically inactive. Mutation of His429 and His532 also resulted in catalytically inactive proteins, and these residues, by analogy with E. coli AP-P, are likely to play a role in shuttling protons during catalysis. These studies indicate that mammalian membrane-bound AP-P has an active-site configuration similar to that of other members of the peptidase clan MG, which is compatible with either a dual metal ion model or a single metal ion in the active site. The latter model is consistent, however, with the known metal stoichiometry of both the membrane-bound and cytosolic forms of AP-P and with a recently proposed model for methionyl aminopeptidase.
Hydroxymethylglutaryl Coenzyme A Reductase Inhibitors Modify the Inflammatory Response of Human Macrophages and Endothelial Cells Infected With <i>Chlamydia pneumoniae</i> (2000)

CSE inhibitors modify the inflammatory response of human immune cells to C. pneumoniae. This finding could be relevant for the therapeutic potential of CSE statins in patients with atherosclerosis and C. pneumoniae infection.
Lafad‐Assisted Plasma Surface Engineering Processes for Wear and Corrosion Protection: A Review (2010)

This chapter contains sections titled: Introduction Ionized Vapor Deposition Technologies Lafad and Hybrid Surface Engineering Systems Lafad-Assisted Processes and Applications Ultra-Thick Coatings and Efficiency of Lafad Process Conclusions
Polyacrylamide sprayed on soil surfaces can stabilize soil aggregates (1996)

Vegetative cover protects soil surfaces and aggregates from erosion caused by the\nimpact of raindrops or sprinkler drops. On bare surfaces, drop impact and wetting causes soil\naggregates to slake, releasing aggregate fragments and/or primary particles that can obstruct\npores at the soil surface and form a depositional seal. The seal reduces infiltration which, in\nturn, increases runoff and soil erosion. Polyacrylamide (PAM) applications, known to stabilize\nsurface soil in irrigated furrows, may effectively stabilize soil aggregates as well. This field\nexperiment evaluated the effects of spray-applied PAM and sprinkler droplet energy on\nsurface soil aggregate stability, measured before and after 31 mm of irrigation. A moderate\ncharge-density, anionic PAM at two nominal rates, 10 and 25 kg ha-1, was applied as a\nsprayed solution to replicated plots of a Portneuf silt loam (coarse silty, mixed, mesic\nDurixerollic Calciorthid) near Kimberly, Idaho, on 25 July, 1995. A linear-move irrigation\nsystem, designed to deliver water to the soil surface at two droplet energy levels, 5 and 15\nJ kg-1, applied a total of 31 mm of water to the plots 7 and 10 days after treatment. Soil\nsamples (0 to 5 mm depth) were taken before and 72 hours after this water was applied.\nGravimetric water content and aggregate stability by wet sieving were measured on these\nsamples. Initially, PAM-treated aggregates visually appeared to resist breakdown under\nsprinkler/drop impact better than non-treated aggregates. PAM applications at economic\nrates increased aggregate stability when droplet energy was 5 J kg-1 but had no effect when\ndroplet energy was 15 J kg-1 .
Simulation Technology for Health Care Professional Skills Training and Assessment (1999)

Changes in medical practice that limit instruction time and patient availability, the expanding options for diagnosis and management, and advances in technology are contributing to greater use of simulation technology in medical education. Four areas of high-technology simulations currently being used are laparoscopic techniques, which provide surgeons with an opportunity to enhance their motor skills without risk to patients; a cardiovascular disease simulator, which can be used to simulate cardiac conditions; multimedia computer systems, which includes patient-centered, case-based programs that constitute a generalist curriculum in cardiology; and anesthesia simulators, which have controlled responses that vary according to numerous possible scenarios. Some benefits of simulation technology include improvements in certain surgical technical skills, in cardiovascular examination skills, and in acquisition and retention of knowledge compared with traditional lectures. These systems help to address the problem of poor skills training and proficiency and may provide a method for physicians to become self-directed lifelong learners.
PrimerSNP: a web tool for whole-genome selection of allele-specific and common primers of phylogenetically-related bacterial genomic sequences (2008)

PrimerSNP is a high-throughput specific primer generation tool for the differentiation of phylogenetically-related strains/species. Experimental validation showed that this software had a successful prediction rate of 80.4 - 100% for strain specific primer design.
Effect of size nonuniformities on the band gap of two-dimensional photonic crystals (1999)

The effects of size nonuniformities in two-dimensional photonic crystals are studied by using the plane-wave expansion and the supercell methods. Square, triangular, and graphite arrays of dielectric rods or air holes are investigated in this study. The reduction of the first photonic band gap in TM or TE modes of square and triangular structures turns out to be not very significant for the amount of size nonuniformities which could occur during fabrication. It is interesting to find that the higher-order absolute photonic band gap existing in the graphite structure is also tolerant to the size fluctuation.
Flexible meta access-control for collaborative applications (1998)

Article Free Access Share on Flexible meta access-control for collaborative applications Authors: Prasun Dewan Department of Computer Science, University of North Carolina, Chapel Hill NC Department of Computer Science, University of North Carolina, Chapel Hill NCView Profile , HongHai Shen IBM Santa Teresa Lab, 555 Bailey Ave, San Jose, CA IBM Santa Teresa Lab, 555 Bailey Ave, San Jose, CAView Profile Authors Info & Claims CSCW '98: Proceedings of the 1998 ACM conference on Computer supported cooperative workNovember 1998 Pages 247–256https://doi.org/10.1145/289444.289499Published:01 November 1998Publication History 27citation672DownloadsMetricsTotal Citations27Total Downloads672Last 12 Months14Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Biochemical topology: From vectorial metabolism to morphogenesis (1991)

In living cells, many biochemical processes are spatially organized: they have a location, and often a direction, in cellular space. In the hands of Peter Mitchell and Jennifer Moyle, the chemiosmotic formulation of this principle proved to be the key to understanding biological energy transduction and related aspects of cellular physiology. For H. E. Huxley and A. F. Huxley, it provided the basis for unravelling the mechanism of muscle contraction; and vectorial biochemistry continues to reverberate through research on cytoplasmic transport, motility and organization. The spatial deployment of biochemical processes serves here as a point of departure for an inquiry into morphogenesis and self-organization during the apical growth of fungal hyphae.
3D-TV Production From Conventional Cameras for Sports Broadcast (2011)

3DTV production of live sports events presents a challenging problem involving conflicting requirements of maintaining broadcast stereo picture quality with practical problems in developing robust systems for cost effective deployment. In this paper we propose an alternative approach to stereo production in sports events using the conventional monocular broadcast cameras for 3D reconstruction of the event and subsequent stereo rendering. This approach has the potential advantage over stereo camera rigs of recovering full scene depth, allowing inter-ocular distance and convergence to be adapted according to the requirements of the target display and enabling stereo coverage from both existing and `virtual' camera positions without additional cameras. A prototype system is presented with results of sports TV production trials for rendering of stereo and free-viewpoint video sequences of soccer and rugby.
A 10 channel coherent optical FDM broadcasting system (2003)

The first demonstration results of a coherent optical frequency-division-multiplexing (FDM) system with a random-access channel selection scheme for CATV distribution application are reported. Indispensable technologies for the FDM coherent transmission such as channel separation locking, random-access channel selection, and polarization diversity were developed and applied to the system. The developed system has suitable features for use as an optical digital CATV, especially for CATV distribution system applications. It is estimated from a 400-Mb/s 10-channel FDM experiment with an 8-GHz frequency separation that 64 channel HDTV signals can be distributed to more than 2000 subscribers without repeaters.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Forensic DNA Profiling Protocols (1998)

In Forensic DNA Profiling Protocols, leading forensic experts from around the world describe in detail their time-proven methods for identity testing through DNA analysis. Their state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The book covers PCR-based test systems, the now widely used STR typing systems (complete with details of both manual and automated detection systems), repeat unit mapping (MVR), direct-phase minisequencing, capillary electrophoresis, and direct blotting. Also fully discussed are the recovery of DNA from a wide range of sample types (blood, semen, skeletal remains, and saliva), species testing, sex determination, and mitochondrial DNA testing. Forensic DNA Profiling Protocols captures and makes practical for all laboratories the whole array of new technologies and techniques that have revolutionized forensic science. The readily reproducible methods elucidated here represent the state-of-the-art for those scientists who want to introduce, establish, and perfect DNA identification techniques in their laboratories
Edge‐sharing SiN<sub>4</sub> Tetrahedra in the Highly Condensed Nitridosilicate BaSi<sub>7</sub>N<sub>10</sub> (1997)

The novel nitridosilicate BaSi7 N10 was obtained by the reaction of barium metal with Si(NH)2 in a special high-frequency furnace at 1650 °C. The single-crystal structure determination (a = 687.29(3), b = 671.29(3), c = 963.28(4) pm, β = 106.269(3)°, PC, Z = 2, R1 = 0.0497, wR2 = 0.0924) reveals a network structure of connected SiN4 tetrahedra. BaSi7 N10 is the first nitridosilicate with both corner and edge-sharing SiN4 tetrahedra. Unlike the situation in normal oxosilicates, vertex-sharing of SiN4 tetrahedra is not exclusively favored over edge-sharing. With a Si:N molar ratio of 7:10, BaSi7 N10 is the most highly condensed multinary nitridosilicate known and has almost the same degree of condensation as binary Si3 N4 .
STUDIES IN THE PHYSIOLOGY OF THE NERVOUS SYSTEM. XXVIII.: ABSENCE OF ALGEBRAIC EQUALITY BETWEEN THE MAGNITUDES OF CENTRAL EXCITATION AND <i>EFFECTIVE</i> CENTRAL INHIBITION GIVEN IN THE REFLEX CENTRE OF A SINGLE LIMB BY THE SAME REFLEX STIMULUS (1924)

I. Two reflex stimuli which evoke antagonistic reflexes in the same pair of antagonistic muscles yield a compound reflex when applied synchronously. At certain intensities of the two stimuli both of the antagonistic muscles contract more in the compound reflex than they were contracted in the state preceding all stimulation. 2. Each reflex stimulus excites one half‐centre ( e.g . flexor), and tends to inhibit any discharge present in the antagonistic half‐centre ( e.g . extensor). The magnitude of the inhibition which actually falls upon any discharging neurones in the inhibited half‐centre may be termed the “effective inhibition” conditioned by the stimulus in question. 3. If excitation is measured in terms of number of synchronous nerve‐impulses by which the discharge of a half‐centre is increased, and effective inhibition in terms of the number of synchronous nerve‐impulses suppressed in the discharge of the antagonistic half‐centre, a direct deduction may be drawn from the observation in paragraph 1. At certain intensities of stimulation, and in the case of at least one of two antagonistic stimuli, the effective inhibition conditioned by it in one half‐centre is less than the excitation conditioned by it in the antagonistic half‐centre. This means that, in the case (for example) of an extension‐reflex, the inhibition of the previously discharging flexor motor neurones is less than the excitation of the extensor motor neurones. 4. The magnitude of inhibition which falls upon any neurones in a half‐centre (whether they be discharging or not) may be termed the “total inhibition” conditioned by a reflex stimulus. 5. If total inhibition is so distributed in a half‐centre that it first falls only upon discharging neurones (and then upon non‐discharging neurones only when all the discharging neurones have been inhibited), the above deduction applies to total inhibition as well as to effective inhibition. But this cannot at present be assumed, for there is no proof that inhibition is so distributed. 6. If total inhibition is so distributed that it falls proportionally upon discharging and non‐discharging neurones in a half‐centre, then some of the inhibition may be spent upon non‐discharging neurones. In this case the effective and the total inhibition in a half‐centre will be of different magnitudes (if the inhibition and excitation in it are sub‐maximal), and inequality between the excitation (in one half‐centre) and the effective inhibition (in the other) given by a single reflex stimulus will not necessarily imply inequality between the excitation and total inhibition given by the same stimulus. That problem remains at issue.
New antitumor antibotics, anguinomycins A and B. (1987)

During the course of our screening program for newantitumor antibiotics, an actinomycete was found that produced two previously unreported antibiotics, which were named anguinomycins A and B. Both of these compounds were highly cytotoxic to murine P388 leukemia cells (IC50 : 0.1 ~0.2 ng/ml) and displayed potent antitumor activity in mice.
Responses against a Subdominant CD8+ T Cell Epitope Protect against Immunopathology Caused by a Dominant Epitope (2010)

CD8(+) T cell responses are critical for the control of virus infections. Following infection, epitope-specific responses establish an unpredictable but reproducible pattern of dominance that is dictated by a large number of both positive and negative factors. Immunodomination, or diminution of subdominant epitope-specific responses by dominant epitopes, can play a substantial role in the establishment of epitope hierarchy. To determine the role of a dominant (K(d)M2(82-90)) and a subdominant (D(b)M(187-195)) epitope of respiratory syncytial virus in viral control and immunodomination, MHC-binding anchor residues in the two epitopes were mutated individually in recombinant infectious viruses, greatly reducing or deleting the epitope-specific CD8(+) T cell responses. Neither mutation negatively affected viral clearance in mice, and compensation by the unmutated epitope was seen in both cases, whereas compensation by five other subdominant epitopes was minimal. Mutation of the dominant K(d)M2(82-90) response resulted in effective viral clearance by the subdominant epitope with less illness, whereas mutation of the subdominant D(b)M(187-195) response resulted in overcompensation of the already dominant K(d)M2(82-90) epitope, and increased severity of illness. Increased illness was associated with poor functionality of the abundant population of CD8(+) T cells specific to the dominant K(d)M2(82-90) epitope, as measured by the percentage and magnitude of IFN-γ production. These data demonstrate efficient viral clearance, and a protective effect of subdominant CD8(+) T cell responses.
Mortality Risk in an Adult Cohort with a Newly Diagnosed Unprovoked Epileptic Seizure: A Population‐Based Study (2000)

There is increased mortality risk in an adult cohort with newly diagnosed unprovoked epileptic seizures. This increase is found in symptomatic patients, young patients, and during the first 2 years after the diagnosis.