gebhart/patrepeval huggingface dataset:
New Class of Carbon‐Nanotube Aerogel Electrodes for Electrochemical Power Sources (2008)

Novel binderless carbon nanotube aerogel (CNAG) electrodes are developed. The materials exhibit a remarkable specific surface area of 1059 m2 g–1 with a special textural porosity with almost equal amounts of mesopores and micropores. These nanostructured CNAG electrodes (see figure) have a wide range of potential applications in electrochemical power sources. The CNAGs great potential as electrodes for supercapacitor applications is demonstrated by a specific capacitance as high as 524 F g–1.
Au-ITO anode for efficient polymer light-emitting device operation (2005)

A thick gold layer is deposited on indium tin oxide (ITO) to improve the interface quality between the ITO anode and the organic layer in organic light-emitting diodes (LEDs). With this improvement, the device with structure ITO/Au/hole-transport-layer(HTL)/poly(p-phenylenevinylene)/Ca/Ag, achieved a lower turn-on voltage from 4 V to about 1.6 V and an increase in luminescence intensity by more than a factor of two at the same voltage. The work function of the Au facilitates the formation of an ohmic contact and good mechanical adhesion to the HTL. The experimental results suggest that the ITO contact limits the supply of current for radiative recombination. The improvement of the device performance is due to the smoother Au surface and the matching of the Au work function with the highest occupied molecular orbital level of adjacent HTL layer.
Determinants of Atherosclerosis Susceptibility in the C3H and C57BL/6 Mouse Model (2000)

Abstract —Lipids, monocytes, and arterial wall cells are primary components involved in atherogenesis. Using the inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H), which have been extensively studied as models of the genetic control of diet-induced atherosclerosis, we examined which of these components determine genetic susceptibility. To test whether dietary responsiveness is involved, a congenic strain of C3H carrying an apoE-null allele (apoE −/− ) was constructed. Although C3H.apoE −/− mice had higher plasma cholesterol levels, they developed much smaller lesions than their B6.apoE −/− counterpart on either chow or Western diets. Reciprocal bone marrow transplantation between the strains, with congenics carrying the same H-2 haplotype, was performed to examine the role of monocytes. The atherosclerosis susceptibility was not altered in the recipient mice, indicating that variations in monocyte function were not involved. Endothelial cells isolated from the aorta of B6 mice exhibited a dramatic induction of monocyte chemotactic protein-1, macrophage colony–stimulating factor, vascular cell adhesion molecule-1, and heme oxygenase-1 in response to minimally modified LDL, whereas endothelial cells from C3H mice showed little or no induction. In a set of recombinant inbred strains derived from the B6 and C3H parental strains, endothelial responses to minimally modified LDL cosegregated with aortic lesion size. These data provide strong evidence that endothelial cells, but not monocytes or plasma lipid levels, account for the difference in susceptibility to atherosclerosis between the 2 mouse strains.
Constructing customised models and providing information to support IT outsourcing decisions (1998)

Information technology (IT) outsourcing is a favourable option for enhancing core organisational competencies/activities. Provident decision making in selecting an optimum IT outsourcing vendor involves judgements about qualitative and quantitative factors. The paper discusses IT outsourcing and proposes a customised computer‐orientated model based on action research and analytical hierarchy process. The aims are to: specify, combine, structure, measure and prioritise key qualitative and quantitative risk elements in IT outsourcing; and provide relevant information to support managers in outsourcing decision making. The results are expected to help managers in minimising business risks and in improving quality of IT outsourcing.
Benign smooth muscle tumours. (1975)

A series of 7748 leiomyomas of the whole body is presented. Ninety-five per cent of lesions occurrred in the female genital tract. Sixty-one of the remaining 371 were rejected because of inadequate histology or uncertainty as to exact site of origin. The 310 cases thus selected were analysed for histology, sex, race, site and age distributions. Comparisons are made between 230 skin lesions, 42 gastric lesions and 5 oral lesions. A further 43 cases of oral lesions were found in an extensive review of the world literature.
Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(<i>S</i>)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography Ligand for Nicotinic Receptors (1999)

The lead compound of a new series of 3-pyridyl ethers, the azetidine derivative A-85380 (3-[(S)-2-azetidinylmethoxy]pyridine), is a potent and selective ligand for the human alpha4beta2 nicotinic acetylcholine receptor (nAChR) subtype. In vitro, the fluoro derivative of A-85380 (2-fluoro-3-[(S)-2-azetidinylmethoxy]pyridine or F-A-85380) competitively displaced [3H]cytisine or [3H]epibatidine with Ki values of 48 and 46 pM, respectively. F-A-85380 has been labeled with the positron emitter fluorine-18 (t1/2 (half-life) = 110 min) by no-carrier-added nucleophilic aromatic substitution by K[18F]F-K222 complex with (3-[2(S)-N-(tert-butoxycarbonyl)-2-azetidinylmethoxy]pyridin-2-yl) tri methylammonium trifluoromethanesulfonate as a highly efficient labeling precursor, followed by TFA removal of the Boc protective group. The total synthesis time was 50-53 min from the end of cyclotron fluorine-18 production (EOB). Radiochemical yields, with respect to initial [18F]fluoride ion radioactivity, were 68-72% (decay-corrected) and 49-52% (non-decay-corrected), and the specific radioactivities at EOB were 4-7 Ci/micromol (148-259 GBq/micromol). In vivo characterization of [18F]F-A-85380 showed promising properties for PET imaging of central nAChRs. This compound does not bind in vivo to alpha7 nicotinic or 5HT3 receptors. Moreover, its cerebral uptake can be modulated by the synaptic concentration of the endogenous ligand acetylcholine. The preliminary PET experiments in baboons with [18F]F-A-85380 show an accumulation of the radiotracer in the brain within 60 min. In the thalamus, a nAChR-rich area, uptake of radioactivity reached a maximum at 60 min (4% I.D./100 mL of tissue). [18F]F-A-85380 appears to be a suitable radioligand for brain imaging nAChRs with PET.
Experiments on the synthesis of Bz-substituted indoles and tryptophans. Part III. The synthesis of the four Bz-chloro-indoles and -tryptophans (1955)

H. N. Rydon and J. C. Tweddle, J. Chem. Soc., 1955, 3499 DOI: 10.1039/JR9550003499
Control of Enzymatic Browning in Processed Mushrooms ( <i>Agaricus bisporus</i> ) (1983)

ABSTRACT Control of polyphenol oxidase (E.C. 1.14.18) activity by the use of citric acid was investigated. The enzyme was inactivated at pH 4.0 and was stable to 10 min exposures at 25°C in the pH range 4.0–8.0. At pH 6.5 the enzyme was active at 45°C but not at 70°C and thermal inactivation followed pseudo first‐order kientics. At pH 6.5 the activation energy (E a ) for enzyme inactivation was 41.1 Kcal/mole while at pH 3.5 two rate constants and hence two values for E a were observed. Between 0–5 min E a for inactivation of polyphenol oxidase was 8.7 Kcal/mole and >5 min Ea was 21.8 Kcal/mole.
Cloning and Characterization of EphA3 (Hek) Gene Promoter: DNA Methylation Regulates Expression in Hematopoietic Tumor Cells (1999)

The Eph family of receptor tyrosine kinases (RTK) has restricted temporal and spatial expression patterns during development, and several members are also found to be upregulated in tumors. Very little is known of the promoter elements or regulatory factors required for expression of Eph RTK genes. In this report we describe the identification and characterization of the EphA3 gene promoter region. A region of 86 bp located at -348 bp to -262 bp upstream from the transcription start site was identified as the basal promoter. This region was shown to be active in both EphA3-expressing and -nonexpressing cell lines, contrasting with the widely different levels of EphA3 expression. We noted a region rich in CpG dinucleotides downstream of the basal promoter. Using Southern blot analyses with methylation-sensitive restriction enzymes and bisulfite sequencing of genomic DNA, sites of DNA methylation were identified in hematopoietic cell lines which correlated with their levels of EphA3 gene expression. We showed that EphA3 was not methylated in normal tissues but that a subset of clinical samples from leukemia patients showed extensive methylation, similar to that observed in cell lines. These results suggest that DNA methylation may be an important mechanism regulating EphA3 transcription in hematopoietic tumors.
Pertussis toxin-sensitive G proteins as mediators of the signal transduction pathways activated by cytomegalovirus infection of smooth muscle cells. (1997)

We demonstrated recently that the arachidonic acid (AA) cascade is involved in cytomegalovirus (CMV)-induced generation of reactive oxygen species (ROS) and the activation of nuclear factor (NF)-kappaB in human smooth muscle cells (SMCs). Since AA release from neutrophils is mediated by pertussis toxin (PTx)-sensitive guanine nucleotide-binding (G) proteins, we hypothesized by analogy that CMV stimulates ROS generation in SMCs and ultimately activates NF-kappaB via a PTx-sensitive G protein-coupled pathway. Our first test of this hypothesis demonstrated that PTx blocked AA release induced by CMV infection of SMCs, as well as blocked the terminal products of this reaction, ROS generation and NF-kappaB activation. More proximal components of the pathway were then examined. CMV infection increased phosphorylation and activity of cytosolic phospholipase A2 (cPLA2), an enzyme causing AA release; these effects were inhibited by PTx. CMV infection activated mitogen-activated protein (MAP) kinase, a key enzyme for cPLA2 phosphorylation, an effect also inhibited by PTx. Finally, inhibition of MAP kinase kinase (MAPKK), which phosphorylates and thereby activates MAP kinase, inhibited CMV-induced ROS generation. These data demonstrate that a PTx-sensitive G protein-dependent signaling pathway mediates cellular effects of CMV infection of SMCs. The downstream events include phosphorylation and activation of MAP kinase by MAPKK and subsequent phosphorylation and activation of cPLA2 (with its translocation to cell membranes), followed by stimulation of the AA cascade, which generates intracellular ROS and thereby activates NF-kappaB.
Laser Pumped Cesium Cell Miniature Oscillator (1996)

Our approach to a low-power compact atomic
oscillator is based on the use of a diode laser to excite a
small cell (-0.1 cm3) containing cesium vapor and buffer
gases. Laser wavelength and power are controlled solely
with current and temperature, providing a compact, low-
power, rugged, spectrally-pure, collimated optical source.
A succession of physics packages, when operated with
analog laboratory electronics, have typically given short
term Allan deviation of o(~)+r”~ 12x10-I’ for
10<~<2OOS. The clock electronics uses a single
microprocessor, with time division multiplexing of the
numerous control loops. A physics package operated
uninterrupted for 285 days with first generation digital
electronics, gave short term ~(2)~“~=2.5~10-‘~ , and
@2)<3xlO-” for z<1x106 s, without removal of drift.
Current designs compatible with a power goal of 300 mW
over a 0 to 50 ‘C temperature range, within a 25 cm3
clock package are showing short term Allan deviation of
(T(2)2”2 < 5x10-“.
Fabrication of optically active flexible polymer films with embedded chain-like arrays of silver nanoparticles (2008)

We report a straightforward method for preparation of freestanding transparent polymer film containing 2D silver nanoparticle arrays and possessing polarization-sensitive optical properties.
Design of an improved set of oligonucleotide primers for genotyping MeCP2tm1.1BirdKO mice by PCR (2007)

We have thus identified a set of three primers that allows for efficient genotyping of the animals by a single PCR reaction. Furthermore, using of this set of primers also resolves a recurrent problem related to the tendency of one of the initial primers to give rise to a non specific band because of its capacity to anneal at both ends of a repeated genomic element which we have identified as MurvyLTR.
Operating Characteristics of Prostate-Specific Antigen in Men With an Initial PSA Level of 3.0 Ng/Ml or Lower (2006)

No AccessJournal of UrologyAdult urology1 Feb 2006Operating Characteristics of Prostate-Specific Antigen in Men With an Initial PSA Level of 3.0 Ng/Ml or Lower I.M. Thompson, D.P. Ankerst, C. Chi, M.S. Lucia, P.J. Goodman, J.J. Crowley, H.L. Parnes, and C.A. Coltman I.M. ThompsonI.M. Thompson More articles by this author , D.P. AnkerstD.P. Ankerst More articles by this author , C. ChiC. Chi More articles by this author , M.S. LuciaM.S. Lucia More articles by this author , P.J. GoodmanP.J. Goodman More articles by this author , J.J. CrowleyJ.J. Crowley More articles by this author , H.L. ParnesH.L. Parnes More articles by this author , and C.A. ColtmanC.A. Coltman More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)00385-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Operating Characteristics of Prostate-Specific Antigen in Men With an Initial PSA Level of 3.0 Ng/Ml or Lower." The Journal of Urology, 175(2), pp. 562–563 References 1 : Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0 ng per milliliter. N Engl J Med2004; 350: 2239. Google Scholar Department of Urology, University of Texas Health Science Center at San Antonio and Southwest Fred Hutchinson Cancer Research Center, and Cancer Research and Biostatistics, Seattle, Washington, University of Colorado, Denver, Colorado, and National Cancer Institute, National Institutes of Health, Bethesda, Maryland© 2006 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 2February 2006Page: 562-563 Advertisement Copyright & Permissions© 2006 by American Urological AssociationMetricsAuthor Information I.M. Thompson More articles by this author D.P. Ankerst More articles by this author C. Chi More articles by this author M.S. Lucia More articles by this author P.J. Goodman More articles by this author J.J. Crowley More articles by this author H.L. Parnes More articles by this author C.A. Coltman More articles by this author Expand All Advertisement PDF downloadLoading ...
Theoretical study on technology threat early warning management (2009)

With the upgrading of technology importance in social-economic development, technology threat has become an important part of an organization's exterior threat. How to effectively identify and assess the threat and its possible impact is directly related to the interests and security of an organization. Up to date, there is little research about technology threat between different organizations. In the present study, we first analyze the technology threat, including its formation mechanism, type classification, manifestation and impact factor. From the perspective of technology development, technology threat can be classified into three types: technology gap threat, technology diversity threat and technology R&D threat. A three-dimensional model of impact factor of technology threat has been constructed. Secondly, we put forward a process of early warning management of technology threat, and build its index system including 6 first-grade indicators and 22 secondary indicators.
Future NASA Earth-Orbiting Radar Missions (1997)

Two Earth-orbiting radar missions are planned in the near future by NASA - Shuttle Radar Topography Mapping (SRTM) and LightSAR.
Effect of Chemotherapy-Induced DNA Repair on Oncolytic Herpes Simplex Viral Replication (2006)

Temozolomide-induced DNA repair pathways vary with MGMT expression and enhance HSV-mediated oncolysis in glioma cells. These findings unveil the potential of HSV to target cells surviving temozolomide treatment.
Ternary single‐source precursors for polycrystalline thin‐film solar cells (2002)

Abstract The development of thin‐film solar cells on flexible, lightweight, space‐qualified substrates provides an attractive cost solution for fabricating solar arrays with high specific power (W kg −1 ). The use of a polycrystalline chalcopyrite absorber layer for thin‐film solar cells is considered as the next generation in photovoltaic devices. At NASA GRC we have focused on the development of new single‐source precursors (SSPs) and their utility to deposit the chalcopyrite semiconducting layer (CIS) onto flexible substrates for solar‐cell fabrication. The syntheses and thermal modulation of SSPs via molecular engineering are described. Thin‐film fabrication studies demonstrate that the SSPs can be used in a spray chemical vapor deposition process for depositing CIS at reduced temperatures, and result in electrical properties that are suitable for photovoltaic devices. Copyright © 2002 John Wiley & Sons, Ltd.
Reduced Instruction Set Architecture for a GaAs Microprocessor System (1986)

Gate densities that permit the integration of an entire microprocessor on a single chip have been reached in GaAs technology. A reduced instruction set computer, or RISC, architecture is well suited to implementation in GaAs because of its low hardware requirements. The large register file and pipelined architecture typical of RISCs complement the high on-chip gate speeds of GaAs by reducing off-chip communication. In late 1984 Texas Instruments and we at Control Data, under DARPA sponsorship, began a one-year project to develop a GaAs microprocessor system with a RISC architecture. The system developed consists of a CPU, a floating-point coprocessor, or FCOP, a memory management unit, or MMU, and a cable. The streamlined architecture minimizes latencies between instructions while allowing for parallel operation between the CPU and the FCOP. The MMU manages that cache to provide a high hit rate. The tight coupling between CPU, FCOP, and MMU achieves a peak throughput of 200 MIPs.
Animal Cell Culture Media (2010)

Abstract Fed‐batch cell culture processes are the standard platform technology for the synthesis of high value biopharmaceutical proteins. Recent advances in cell line development and in the optimization of culture medium have enabled the operation of fed‐batch processes at significantly higher volumetric productivities than previously realized. While a robust basal medium is essential to ensure high productivity, a well‐developed feed medium coupled with an appropriate feeding strategy are essential for sustaining it over the course of the culture duration. Furthermore, optimization of cell culture medium needs to be cognizant of specific goals for its use. Different optimization strategies are adapted for developing platform media applicable for multiple cell lines and customized media developed for specific cell lines. While volumetric productivity continues to be an important parameter for cell culture medium optimization, the developed medium should also be robust during implementation in biopharmaceutical manufacturing facilities. The developed medium should be easy to prepare and have a long shelf life to ensure ease of process implementation in multiple commercial and clinical‐scale manufacturing sites. Due care should be taken to ensure that optimization of media does not lead to unacceptable alterations in the quality of the expressed protein. This article will address all these aspects that ensure the efficient optimization and implementation of animal cell culture media.
Comparison of optimum and sub-optimum turbo decoding schemes in 3rd generation cdma2000 mobile system (2003)

The performance of optimum and sub-optimum turbo decoding schemes in the 3rd generation cdma2000 mobile system is evaluated in this paper. The turbo code is recommended as a channel coding scheme in cdma2000 for data rates higher than 14.4 kbps due to its superior performance over the conventional convolutional code. We compare the performance of turbo codes using optimum log-MAP decoder and sub-optimum max-log-MAP and SOVA decoding schemes in direct spread forward link (from BS to MS). Different multipath channel environments are studied with Monte-Carlo simulations. The effect of channel estimation is also addressed. The performance of turbo codes is compared to conventional convolutional coding. It is shown that in practical system the performance of sub-optimum max-log-MAP decoder is comparable to log-MAP.
Changes in Land Holdings Consequent to the Abolition of the Intermediaries (1968)

Land Economics/Use
Effect on intake and production of dairy cows of feeding three high‐moisture silages having different fermentation characteristics (1974)

Abstract Three degress of consolidation and air exclusion were imposed by vacuum compression during the making of three 60 tonne stacks of silage from a common source of mixed pasture grasses. Maximum air exclusion resulted in a silage having lowest pH and butyric acid and highest lactic acid content. When the three silages were fed as sole diets to lactating dairy cows intake was about 12% lower and butterfat yield about 14% lower on the silage from which air had been most effectively removed.
Resource allocation for network-integrated device-to-device communications using smart relays (2013)

With increasing number of autonomous heterogeneous devices in future mobile networks, an efficient resource allocation scheme is required to maximize network throughput and achieve higher spectral efficiency. In this paper, performance of network-integrated device-to-device (D2D) communication is investigated where D2D traffic is carried through relay nodes. An optimization problem is formulated for allocating radio resources to maximize end-to-end rate as well as conversing QoS requirements for cellular and D2D user equipment under total power constraint. Numerical results show that there is a distance threshold beyond which relay-assisted D2D communication significantly improves network performance when compared to direct communication between D2D peers.