gebhart/patrepeval huggingface dataset:
Linear matrix inequalities in analysis with multipliers (2005)

We show that a number of standard robustness tests can be reinterpreted as special cases of the application of the passivity theorem with the appropriate choice of multipliers. We show how these tests can be performed using convex optimization over linear matrix inequalities.
Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer (2017)

A study of mouse models of breast cancer suggests that the microenvironment of an established primary breast cancer affects susceptibility to neoadjuvant chemotherapy.
Molecular cloning and genetic mapping of the t complex responder candidate gene family. (1990)

Male transmission ratio distortion (TRD) is a property of mouse t haplotypes requiring the t complex responder locus (Tcr). Tcr maps to the central region of t haplotypes, and is embedded within a series of large duplicated tracts of DNA known as "T66 elements." In previous work, a family of genes (the "T66" genes) was identified within this region that encodes male germ cell-specific transcripts. Genetic and molecular data indicate that one of these genes represents Tcr. Here, we describe the molecular cloning of the four members of the T66 gene family, the genetic mapping of these genes to three adjacent t haplotype loci, and comparative restriction enzyme analysis of the genes. The results indicate that these genes are highly similar to one another, and were created by recent, complex duplication events. This suggests that a minor alteration(s) could have been responsible for conferring "mutant" responder activity upon Tcr, while the other homologs retained "wild-type" biochemical function. In addition, we have identified and mapped three T66 genes in wild-type t complexes. They reside in two separate loci at the opposite ends of the proximal t complex inversion, and are separated by at least 3 cM.
Improved surface adhesion and coverage of perfluoropolyether lubricants following far-UV irradiation (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTImproved surface adhesion and coverage of perfluoropolyether lubricants following far-UV irradiationDavid D. Saperstein and L. Judy LinCite this: Langmuir 1990, 6, 9, 1522–1524Publication Date (Print):September 1, 1990Publication History Published online1 May 2002Published inissue 1 September 1990https://pubs.acs.org/doi/10.1021/la00099a016https://doi.org/10.1021/la00099a016research-articleACS PublicationsRequest reuse permissionsArticle Views317Altmetric-Citations60LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Epitaxial Growth of ZnS on Si by Metal Organic Chemical Vapor Deposition (1985)

This paper presents a new method of growing ZnS on Si substrates using metal organic chemical vapor deposition (MOCVD). The method includes the simple process of depositing a thin ZnS buffer layer on an Si(111) substrate prior to the ZnS growth. The ZnS buffer layer is prepared by electron-beam-evaporation at 220°C or MOCVD growth above 500°C, and the most suitable thickness of the layer is about 100 Å. The ZnS film prepared on the layer exhibits a reflection high-energy electron diffraction pattern which consists of elongated spots, indicating good surface morphology.
Approximate simulation of CO<sub>2</sub> and H<sub>2</sub>s absorption into aqueous alkanolamines (1993)

Abstract Rigorous and approximate methods are compared for the simulation of CO 2 absorption into aqueous alkanolamine mixtures of methyldiethanolamine and diethanolamine. In addition, data for the mixtures containing monoethanolamine and the simultaneous absorption of CO 2 and H 2 S are presented. For the rigorous approach, the simplified eddy diffusivity theory is used to simulate the liquid‐phase hydrodynamic characteristics. The approximation methods examined are the pseudo‐first‐order approximation, the interpolation approximation of Wellek et al. (1978), the algebraic combined flux (ACFLUX) approximation and the modified combined flux (MCFLUX) approximation. The latter approximation utilizes the reaction zone concept to determine the kinetic preference of the absorbing gas at the gas‐liquid interface. Under the range of conditions studied, the MCFLUX approximation predicts very accurately the CO 2 and H 2 S flux rates in mixed amine systems, as compared with the rigorous solution of the differential equations.
Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis. (1992)

Escherichia coli endotoxin (LPS) can induce the clinical syndrome of septic shock and renal cortical necrosis and can stimulate nitric oxide (NO) production from macrophages, vascular smooth muscle, and glomerular mesangial cells in vitro. NO is an endogenous vasodilator, which also inhibits platelet aggregation and adhesion. We therefore sought to determine whether LPS would stimulate NO production in vivo and, if so, whether this NO would modulate endotoxin-induced glomerular thrombosis. The stable NO end-products, NO2 and NO3, were measured in serum and urine collections from rats during baseline and after injection of LPS, with or without substances that modulate NO synthesis. The urinary excretion of NO2/NO3 was 1,964 +/- 311 nm/8 h during the baseline and increased to 6,833 +/- 776 nm/8 h after a single intraperitoneal injection of 0.1 mg/kg LPS (P < 0.05). The serum concentration of NO2/NO3 also significantly increased after LPS injection. Both the urine and serum stimulation was significantly prevented by the NO synthesis inhibitor, Nw-nitro-L-arginine methyl ester (L-NAME). L-Arginine, given with LPS+L-NAME significantly restored the NO2/NO3 levels in the urine. Ex vivo incubation of tissues from rats treated with LPS demonstrated NO production by the aorta, whole kidney, and glomeruli, but not cortical tubules. Histological examination of kidneys from rats given either LPS or L-NAME alone revealed that 2 and 4.5% of the glomeruli contained capillary thrombosis, respectively. In contrast, rats given LPS+L-NAME developed thrombosis in 55% of glomeruli (P < 0.001), which was significantly prevented when L-arginine was given concomitantly. We conclude that LPS stimulates endogenous production of NO in vivo and that this NO is critical in preventing LPS-induced renal thrombosis.
3-Hydroxymethyleneoxindole and its Derivatives (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT3-Hydroxymethyleneoxindole and its DerivativesErnest Wenkert, John H. Udelhofen, and Naba K. BhattacharyyaCite this: J. Am. Chem. Soc. 1959, 81, 14, 3763–3768Publication Date (Print):July 1, 1959Publication History Published online1 May 2002Published inissue 1 July 1959https://pubs.acs.org/doi/10.1021/ja01523a068https://doi.org/10.1021/ja01523a068research-articleACS PublicationsRequest reuse permissionsArticle Views526Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of Sarilumab on Rheumatoid Arthritis as Reported by Patients Using the Rheumatoid Arthritis Impact of Disease Scale (2019)

Based on the RAID, sarilumab + csDMARD or as monotherapy reduced the effect of RA on patients' lives to a greater extent than placebo + csDMARD or ADA monotherapy. (ClinicalTrials.gov: NCT01709578 and NCT02332590).
Polymerization of vinyl monomers initiated by chromium(II) acetate + organic peroxides (1978)

The redox initiator systems consisting of chromium(II) acetate (Cr2+) and organic peroxides are studied in dimethylformamide (DMF) at low temperatures. The second-order rate constants of reduction of benzoyl peroxide (BPO) with Cr2+ are 0.65, 0.24 and 0.075 dm3 mol–1 min–1 at –10, –20 and –28°C, respectively.The activity of organic peroxides for the redox polymerization of methyl methacrylate (MMA) at –28°C decreases in the following order; hydroperoxide > diacylperoxide > perester = dialkyl peroxide.The kinetics of polymerization of MMA are different from that of a conventional free-radical polymerization. The dependence of the initial rate of polymerization (Rp) on the concentrations of initiator components, Cr2+ and BPO, is very small; the kinetic orders are 0.1 and 0.2, respectively. However, Rp is proportional to the square of the concentration of MMA. This result is explained in terms of a primary radical termination.The polymerization of MMA with the Cr2++ BPO system is found to occur continuously without a dead end polymerization after red Cr2+ changed to blue Cr3+, i.e., after Cr2+ was consumed by the redox reaction with BPO. The degree of polymerization of PMMA obtained by this initiator system below 30°C increases with an increase in monomer conversion.
Highly Regioselective Thiocarbonylation of Conjugated Dienes via Palladium-Catalyzed Three-Component Coupling Reactions (2000)

Three-component coupling reaction of conjugated dienes, thiols, and carbon monoxide affords an atom-economical thiocarbonylation of the dienes to give beta,gamma-unsaturated thioesters as the sole products. A catalyst system based on [Pd(OAc)(2)] and Ph(3)P showed excellent catalytic activity. The thiocarbonylation was performed under an atmosphere of carbon monoxide (400 psi) at 110 degrees C in CH(2)Cl(2) for 60 h. A wide variety of thioesters were synthesized in good to excellent yields from easily accessible starting materials. The reaction is believed to proceed via a eta(3)-allylpalladium intermediate. The thiocarbonylation, which is applicable to a wide variety of conjugated dienes, occurs in high regioselectivity, the latter dependent on the steric characteristics and stability of the eta(3)-allylpalladium complex.
Time-Lapse Interferometry and Contouring Using Television Systems (1971)

A novel approach to time-lapse interferometry and contouring is introduced that uses television rather than photographic techniques. A first interferogram is stored on a video storage device such as a magnetic disk. After a change in the stress of the object, a second interferogram is electronically compared to the stored pattern to form a signal representative of the fringe pattern caused by the deformation. This signal may be directly displayed on a cathode-ray tube or employed by some automatic inspection device.
Considerations and Methodology for TrialingZiconotide (2010)

All 3 methods of ziconotide trialing appear to be viable options, and no method can be considered superior on the basis of the evidence presented in this review. Controlled studies comparing ziconotide trialing methods may be warranted.
Lung lymph capillary injury-related protease (1989)

Capillary damage induced in sheep by intravenous infusion of Escherichia coli endotoxin, oleic acid, or air emboli causes the appearance in lung lymph of a serine protease with trypsin-like activity. The time course of the appearance of the enzyme and the extent of its activity increase indicate a close association with capillary injury. The enzyme was isolated from active lymph after a 9,000-fold purification by affinity chromatography on Reactive Blue-agarose, aprotinin-agarose, and p-amino-benzamidine-agarose columns. The protein, molecular mass of 70-75 kDa, is composed of two polypeptide chains of 31 and 43 kDa linked by disulfide bonds. Studies with synthetic peptide and thioester substrates showed preferential cleavage of substrates having two or more basic amino acids and the importance for activity of secondary enzyme-substrate interactions at sites removed from the scissile bond. The specificity of the enzyme and its pattern of sensitivity to inhibition by a series of isocoumarin derivatives distinguish it from enzymes of the clotting and complement systems and also from tissue plasminogen activator and lung and skin tryptase. The origin of the enzyme, its role in capillary damage, and its physiological function remain to be established.
The cyber dimension of corporate investigations: insights of a 21st century sleuth (2006)

If you are late, it could get overwritten Dario Forte and Richard Power grill the founder of the New York City FBI computer crime squad, Ed Stroz about corporate investigations. Ed Stroz believes that computer expertise is fundamental to any investigation. He said that clients need investigators who will know if computerized evidence exists, where it is and how it must be preserved. He believes that the information age has made investigation easier, but only if you have the expertise to do it properly. A computer evidence trail can demonstrate more clearly someone's actions, than surveillance ever could, he says. Often a private investigator with base-line computer expertise is needed to work hand-in-hand with a computer forensics expert. You need to know basics like how packet-switched networks operate, how servers and blackberries communicate, how printers store data and so on. He says that sometimes executives expect staff from the IT department to be computer forensic examiners. A big problem is the delayed reaction in getting the right expertise. If a computer forensic examiner is brought in too late, then sometimes the data needed for evidence has been overwritten, warns Stroz who is now a managing partner of Stroz Friedberg. He also recommends that it is important to have lawyers advising early on. Getting ahead of the curve on cyber forensics, e-discovery and other challenging aspects of corporate investigations into malfeasance (whether perpetrated by insiders or outsiders) is one of the most vital tasks that confronts 21st Century information security professionals. Our intensive coverage of these important issues continues this month, as we conduct an in-depth interview with a leader in the field.
<i>Myasthenia Gravis and the Tops and Bottoms of AChRs</i> (2008)

The main immunogenic region (MIR), against which half or more of the autoantibodies to acetylcholine receptors (AChRs) in myasthenia gravis (MG) or experimental autoimmune MG (EAMG) are directed, is located at the extracellular end of alpha1 subunits. Rat monoclonal antibodies (mAbs) to the MIR efficiently compete with MG patient autoantibodies for binding to human muscle AChRs. Antibodies bound to the MIR do not interfere with cholinergic ligand binding or AChR function, but target complement and trigger antigenic modulation. Rat mAbs to the MIR also bind to human ganglionic AChR alpha3 subunits, but MG patient antibodies do not. By making chimeras of alpha1 subunits with alpha7 subunits or ACh binding protein, the structure of the MIR and its functional effects are being investigated. Many mAbs to the MIR bind only to the native conformation of alpha1 subunits because they bind to sequences that are adjacent only in the native structure. The MIR epitopes recognized by these mAbs are not recognized by most patient antibodies whose epitopes must be nearby. The presence of the MIR epitopes in alpha1/alpha7 chimeras greatly promotes AChR expression and sensitivity to activation. EAMG can be suppressed by treatment with denatured, bacterially expressed mixtures of extracellular and cytoplasmic domains of human alpha1, beta1, gamma, delta, and epsilon subunits. A mixture of only the cytoplasmic domains not only avoids the potential liability of provoking formation antibodies to pathologically significant epitopes on the extracellular surface, but also potently suppresses the development of EAMG.
α‐Alumina Fiber with Platelet Morphology Through Wet Spinning (2011)

Highly loaded Al(OH) 3 slurries were prepared in a 2 vol% aqueous acetic acid medium up to 33.3 wt% powder loading. The slurries were blended with 4 wt% chitosan in 2 vol% acetic acid and formed into ceramic fibers through wet spinning in sodium tripolyphosphate ( STPP ) bath. A gelation kinetics study of the chitosan‐blended slurry also showed instantaneous gelation behavior under oscillatory mode rheological measurement. The slurries with moderate viscosities up to 150 Pa·s were spinnable in STPP bath due to ionotropic gelation. Low viscous slurries were formed into a lump during spinning due to low powder loading and less chitosan present in the blend. The green fibers crystallized into α‐alumina during sintering at ~950°C with an average diameter varying between 70 and 120 μm. α‐alumina platelets were formed at 1350°C and changed to hexagonal platelets at 1550°C. The crystallite size of α‐alumina varied between 26 and 112 nm which was measured from XRD data using Scherrer formula. The grain size of sintered fibers was ~4.5 μm at 1350°C. The fibers were assembled into a cylindrical scaffold and sintered to produce a crushing strength of 0.9 MPa with density 0.9 g/cm 3 .
One-pot synthesis of 2-(trifluoromethyl)pyridines from N-silyl-1-aza-allyl anions with trifluoroacetylketene diethyl ketal or (E )-1,1,1-trifluoro-4-phenylbut-3-en-2-one (1999)

The reaction of N-silyl-1-aza-allyl anions with trifluoroacetylketene diethyl ketal and (E)-1,1,1-trifluoro-4-phenylbut-3-en-2-one are described. The anions, which were prepared from an α-silyl carbanion of 3-methyl-5-(trimethylsilylmethyl)isoxazole [or 3-methyl-2-(trimethylsilylmethyl)pyridine] and para-substituted benzonitriles (R = H, p-Me, p-OMe, p-Cl, p-CF3), reacted with a slight excess of trifluoroacetylketene diethyl ketal or (E)-1,1,1-trifluoro-4-phenylbut-3-en-2-one in dry tetrahydrofuran to afford the corresponding 2-(trifluoromethyl)pyridine derivatives in 75, 71, 78, 48, 46, 60, 83% yield, respectively.
Anisotropic diffusion regularization methods for diffuse optical tomography using edge prior information (2006)

Diffuse optical tomography ( DOT) is a non-invasive functional imaging modality that aims to image the optical properties of biological organs. The forward problem of the light propagation of DOT can be modelled as a diffusion process and is expressed as a differential diffusion equation with boundary conditions. The solution of the DOT inverse problem can be formulated as a minimization of some functional that measures the discrepancy between the measured data and the data produced by representation of the modelled object. The minimization of this term alone would force the solution to be consistent with the data and the solver used for this purpose. But since in practice data are always accompanied with noise and with some jump discontinuities, these will unavoidably yield unsatisfactory solutions, so some regularization to restore the solution is required. In this paper we introduce an anisotropic regularization term using a priori structural information about the object. This term aims to reduce the noise associated with the data and to preserve the edges in the solution by a combined strategy using the a priori edge information and the diffusion flux analysis of the local structures at each iteration. To accelerate the iterative solver we use a particular method called the lagged diffusivity Newton-Krylov method. The whole proposed strategy, which makes use of a priori diffusion information has been developed and evaluated on simulated data.
Reviews of Books (1997)

Reviews of Books Get access Atlas de la Révolution française Volume 8. Populaion. By Bernard Lepetit and Maroula Sinarellis. Paris: EHESS. 1995. 92 pp. Ffr 120. ISBN 2 7132 1189 1. Atlas de la généralité de Paris au 18e siècle: un paysage retrouvé By Mireille Touzery. Paris: Comité pour I'histoire économique et financiére de la France. 175 pp. Ffr 350. ISBN 2 11 087169 5. ALAN FORREST ALAN FORREST University of York Search for other works by this author on: Oxford Academic Google Scholar French History, Volume 11, Issue 1, March 1997, Pages 84–86, https://doi.org/10.1093/fh/11.1.84 Published: 01 March 1997
Review: <i>Cytogenetics: An Introduction</i>, by E. D. Garber (1973)

Book Review| February 01 1973 Review: Cytogenetics: An Introduction, by E. D. Garber Cytogenetics: An IntroductionE. D. Garber Adolph Hecht Adolph Hecht Search for other works by this author on: This Site PubMed Google Scholar The American Biology Teacher (1973) 35 (2): 103–104. https://doi.org/10.2307/4444242 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Adolph Hecht; Review: Cytogenetics: An Introduction, by E. D. Garber. The American Biology Teacher 1 February 1973; 35 (2): 103–104. doi: https://doi.org/10.2307/4444242 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe American Biology Teacher Search This content is only available via PDF. Copyright 1972 National Association of Biology Teachers Article PDF first page preview Close Modal You do not currently have access to this content.