gebhart/patrepeval huggingface dataset:
Machine-Learning-Based Identification of Defect Patterns in Semiconductor Wafer Maps: An Overview and Proposal (2014)

Wafers are formed from very thin layers of a semiconductor material, hence, they are highly susceptible to various kinds of defects. The defects are most likely to occur during the lengthy and complex fabrication process, which can include hundreds of steps. Wafer defects are generally caused by machine inaccuracy, chemical stains, physical damages, human mistakes, and atmospheric conditions. The defective chips tend to have several unique spatial patterns across the wafer, namely ring, spot, repetitive and cluster patterns. To locate such defect patterns, wafer maps are used to visualize and ultimately lead to better understanding of what happened during the process failure. To identify the unique patterns of defects and to find the point of manufacturing process that causes such defects accurately, nature-inspired model-free machine-learning techniques have been well accepted. This paper thus reviews the theoretical and experimental literature of such models with a focus on model learnability and efficiency-related issues involving data reduction and transformation techniques, which could be seen as the key model properties to deal with big data applications.
Silicon-Germanium-Boron Ternary Amorphous Alloy (1982)

Highly conductive ternary amorphous films are prepared by thermal decomposition of silane-germane-diborane mixtures in a low-pressure furnace at 500°C. The conductivity of the amorphous silicon-germanium-borom alloy exceeds the previously obtained limit for amorphous silicon, and increases with increasing germanium content. The d.c. conductivity and the Seebeck coefficient are measured at above room temperature. Measurements of the a.c. conductivity, optical absorption and E.S.R. are made at room temperature. The carrier transport is well described by a variable-range-hopping model. Evidences for a band model similar to that for the semimetal are proposed for the ternary amorphous alloy. In a higher germanium content film, the structure transforms into a microcrystalline one. The conductivity of microcrystalline silicon-germanium-boron alloy attains 10 3 S·cm -1 .
Statics and Kinematics of Granular Materials (1992)

This book outlines the basic science underlying the prediction of stress and velocity distributions in granular materials. It takes the form of a textbook suitable for postgraduate courses, research workers and for use in design offices. The nature of a rigid-plastic material is discussed and a comparison is made between the Coulomb and conical (extended Von Mises) models. The methods of measuring material properties are described and an interpretation of the experimental results is considered in the context of the Critical State Theory. The book will be an invaluable text for all those working with or doing research into granular materials. Exercises and solutions are provided which will be particularly useful for the student.
[Clay ratio as a tracer to assess the origin of soil-derived dust]. (2005)

The objectives of this research are to characterise the mineralogy of soil-derived dust in Northern China and to set up the mineralogical signature to trace their origin. Mineral composition of aerosol particles is investigated at five sites (Aksu, Dunhuang, Yulin, Tongliao and Changwu) during the intensive field campaign period of ACE-Asia. The results show that the Kaolinite (K) to Chlorite (C) ratio is sensitive to the regional origin of Asian dust. Western source areas (represent by Aksu) displayed the lowest K/ C ratio of 0.3 (in average), while it was found that to increase up to 0.70 (in average) as moving towards north source areas (represent by Yulin). By studying transported dust in a depositional area representative of the Chinese Loess Plateau, the usefulness of the K/C ratio to retrieve the origin of the dust by associating it with back air-mass trajectories is checked. Compared the mineralogical data between Asian dust and Sahara dust, it is shown that K/C ratio is also a good signature to identify the source areas on the global scale.
<scp>l</scp>-DNA Molecular Beacon: A Safe, Stable, and Accurate Intracellular Nano-thermometer for Temperature Sensing in Living Cells (2012)

Noninvasive and accurate measurement of intracellular temperature is of great significance in biology and medicine. This paper describes a safe, stable, and accurate intracellular nano-thermometer based on an L-DNA molecular beacon (L-MB), a dual-labeled hairpin oligonucleotide built from the optical isomer of naturally occurring d-DNA. Relying on the temperature-responsive hairpin structure and the FRET signaling mechanism of MBs, the fluorescence of L-MBs is quenched below the melting temperature and enhanced with increasing temperature. Because of the excellent reversibility and tunable response range, L-MBs are very suitable for temperature sensing. More importantly, the non-natural L-DNA backbone prevents the L-MBs from binding to cellular nucleic acids and proteins as well as from being digested by nucleases inside the cells, thus ensuring excellent stability and accuracy of the nano-thermometer in a complex cellular environment. The L-MB nano-thermometer was used for the photothermal study of Pd nanosheets in living cells, establishing the nano-thermometer as a useful tool for intracellular temperature measurement.
Studies on the guinea pig pancreas. Parallel discharge of exocrine enzyme activities. (1975)

An in vitro system of guinea pig pancreatic lobules convenient for the study of secretory processes is described in this paper. In this system: (a) the over-all glandular architecture of the tissue is preserved: lobules remain morphologically intact through 5 hours; (b) amylase discharge from unstimulated lobules is low (similar to 4%/hour) and linear over the 5 hours tested; (c) response to carbamylcholine chloride (10-5 M) is energy-dependent, rapid, and extensive (92% discharge of amylase by 5 hours); (d) initial rates of discharge remain stable over the first 3 hours; and (e) no autoactivation of zymogens occurs in incubation medium or tissue. The activation of four zymogens, i.e. chymotrypsinogen, trypsinogen, and procarboxypeptidases A and B, was studied using the following criteria for optimal activation: (a) maximal activation attainable under experimental conditions; (b) stability at the level of maximal activation; and (c) linear relationship between amounts of protein activated and enzyme activity elicited by activation. The concentration of activators (trypsin or enterokinase) and secretory protein, the presence or agents (bovine plasma albumin or Triton X-100) which minimize adsorptive losses of secretory protein on glass or plastic surfaces, and the temperature at which activation is carried out were found to be critical and different for each of the zymogens tested. The kinetics of the appearance of three enzyme activities (amylase, lipase, and ribonuclease) and four potential proteolytic activities (chymotrypsinogen, trypsinogen, and procarboxypeptidases A and B) into the incubation medium was studied under different conditions; i.e. rest and stimulation with various secretogogues (carbamylcholine chloride, caerulein, and pancreozymin). All seven activities estimated to represent similar to 75% of the secretory protein output of the exocrine pancreas were discharged in synchrony and in constant proportions and were released from the tissue to the same extent under each experimental condition investigated.
Vortex Suppressors Reduce Probe Vibrations (1988)

Lightweight addition to probe reduces cyclical stress aerodynamically. Life expectancy of instrumentation probe for high-speed flow increased by addition of helical strakes to cylindrical shield surrounding probe. Strakes disrupt vortex shedding normally occuring in fast flows around cylindrical body.
Rats with a Glucocorticoid‐Induced Catabolic State Show Symptoms of Oxidative Stress and Spleen Atrophy: The Effects of Age and Recovery (2002)

In this study we wanted to determine whether changes in antioxidant profile could follow the catabolic effects of glucocorticoids. We also wanted to compare resistance to glucocorticoid overload in young and old rats. To address these questions, whole body catabolism was induced by the administration of dexamethasone (Dex) at either 2 mg/kg bodyweight/day to young (6 weeks old) or 0.5 mg/kg body-weight/day to old (94 weeks old) rats. Bodyweight loss of pair-fed rats not given Dex was only 2% in the young rats and 8% in the old rats, whereas in Dex-treated rats the decrease in bodyweight was 22% in the young rats and 13% in the old rats after 5 days of treatment. Spleen weight decreased by 65% in the young rats and by 52% in the old rats. Additionally, in the young rats there was a 46% reduction in glutathione (GSH) in erythrocytes as well as a 36% reduction in GSH/tissue wet weight in the soleus muscle. The corresponding figures for the old rats were 35 and 26%, respectively. Taken together, these results suggest that Dex directly and/or indirectly impaired the antioxidant reactions. This was further confirmed by a significant (50%) decline in Cu-Zn superoxide dismutase (SOD-1) activity in erythrocytes isolated from the young rats treated with Dex but not the old rats as they showed a significant elevation in SOD-1 activity (by 101%). Thiobarbituric acid reactant substances were significantly higher in both young and old rats. Activity of blood plasma creatine kinase increased by 73% in the young rats and by 307% in the old rats treated with Dex. Although both the young and the old rats could recover from oxidative stress, the old rats in contrast to the young rats remained catabolic until the end of the experiment. In conclusion, we suggest that old rats are more vulnerable to the catabolic action of Dex, whereas young rats are more susceptible to the oxidative stress induced by Dex.
Differential release of high mannose structural isoforms by fungal and bacterial <i>endo</i> -β- <i>N</i> -acetylglucosaminidases (2012)

Endo-β-N-acetylglucosaminidases (ENGases) are widely used to remove N-linked oligosaccharides from glycoproteins for glycomic and proteomic studies and biopharmaceutical processes. Although several ENGases are widely available and their main oligosaccharide structural preferences are generally known (i.e. high mannose, hybrid or complex), the preferences of ENGases from different kingdoms for individual structural isoforms within the major classes of N-linked oligosaccharides have previously not been compared. In this work, a fungal ENGase (Endo Tv) was purified for the first time from a commercial Trichoderma viride chitinase mixture by sequential anion exchange and size exclusion chromatography, a commonly used strategy for purification of chitinases and endo enzymes. Oligosaccharides released from substrate glycoproteins by Endo Tv were identified and quantified by high pH anion exchange chromatography with pulsed amperometric detection and verified by mass spectrometric analysis. Unlike the widely-used bacterial ENGases, Endo H and Endo F1, Endo Tv released exclusively high mannose N-linked oligosaccharides from RNase B, ovalbumin, and yeast invertase. Endo Tv did not hydrolyze fucosylated, hybrid, complex type or bisecting N-acetylglucosamine-containing structures from bovine fetuin, ovalbumin and IgG. When compared to the bacterial ENGase, Endo H, the relative ratio of high-mannose oligosaccharide structural isoforms released from RNase B by Endo Tv was found to differ, with Endo Tv releasing more Man₅GlcNAc and Man₇GlcNAc isoform I and less Man(9)GlcNAc from RNase B. Based on these data, it is suggested that use of ENGases from multiple sources may serve to balance an introduced bias in quantitative analysis of released structural isoforms and may further prove valuable in biochemical structure-function studies.
Electronic Ballasts for Metal Halide Lamps (1988)

(1988). Electronic Ballasts for Metal Halide Lamps. Journal of the Illuminating Engineering Society: Vol. 17, No. 2, pp. 131-140.
Kinetic selection of HPV 16 E6/E7-directed antisense nucleic acids: anti-proliferative effects on HPV 16-transformed cells (1999)

The E6/E7-coding sequences of the human papillomavirus type 16 (HPV 16) were probed for kinetic accessibility in vitro by pools of catalytic antisense RNA. Only long-chain complementary RNA and very few antisense sequences with a 3' portion complementary to a 10 nt window within unspliced and spliced E6-coding target sequences showed fast annealing with k(ass) values of up to 10(4) M-1s-1 indicating that the majority of E6/E7 RNA sequences are unfavourable targets for antisense inhibitors and ribozymes. Fast-annealing antisense oligodeoxyribonucleotides directed against the window of 10 nt inhibited cell proliferation of HPV 16-transformed SiHa cells but not slow-annealing antisense species. Antisense RNA of several hundred nucleotides in length also showed significant anti-proliferative activity. Biological effects of antisense oligodeoxyribonucleotides were specific for the antisense sequence, could only be found in HPV-positive but not in HPV-negative cell lines, and were related to decreased levels of E7 protein and E6/E7-specific transcripts. This work suggests that HPV 16 E7/E6 sequences exhibit a low accessibility for antisense oligonucleotides. This can be overcome, however, by exploiting the relationship between fast annealing of antisense species and their increased efficacy in human cells.
Nucleosides. 127. Synthesis of Pyrido[2,3-d]pyrimidine Nucleosides from 5-Cyanouridine (1984)

Abstract 7-Amino-6-substituted-1-(β-D-ribofuranosyl)pyrido [2,3–d]pyrimidine-2,4 (1H, 3H)-diones were prepared in good yields from 5-cyanouridine by application of a novel ring transformation reaction recently developed in our laboratory. Treatment of 3-benzyloxymethyl-2', 3'-O-isopropylidene-5'-O-trityl-5-cyanouridine with malononitrile, cyanoacetamide or ethyl cyanoacetate in base gave directly the pyridopyrimidine nucleosides bearing a CN, CONH2 and CO2 Et at C-6, respectively. The benzyloxymethyl and trityl protecting groups were removed by hydrogenolysis and the isopropylidene group by acid hydrolysis.
Laser mode selection with intracavity phase elements (2004)

Several methods for operating a laser with a single high-order transverse mode are presented. These methods are based on the insertion of binary and spiral phase elements within the laser resonator, so as to introduce high losses to the undesired modes and low losses to the desired mode, as well as controlling the phases of the various lobes of the high order mode distribution. The basic principles and experimental results are presented, demonstrating efficient high order mode selection in various Nd:YAG and CO/sub 2/ laser configurations, where the far-field intensity distribution is comprised mainly of a dominant main lobe. The experiments were performed with low gain CW lasers as well as short-pulse-high-gain Q-switched lasers.
Action of Drugs, Detergents, and Monomers on Liposomes (1982)

Interactions of 14 organic compounds, such as phenols, aromatic carboxylic acids, steroids, and methacrylates with the multi-lamellar lecithin-cholesterol liposomes, were monitored in biological systems. It was found that their actions with our artificial liposomes were quite similar to those of biological membranes described previously.
Notes on the simulation of evolution (1994)

The simulation of evolution for the purposes of parameter optimization has generally demonstrated itself to be a robust and rapid optimization technique. But there may exist more value in simulating evolution than simple parameter optimization. The optimizations of system behavior obtained through simulated evolution represent a potentially powerful autopoetic pathway to machine learning and self-organization. Indeed, it may eventually prove to be the only practical path to the development of ontogenetic machine intelligence. As the complexity of the systems being evolved increases, the development of a proper philosophy of analysis and design becomes imperative. The designer of evolutionary algorithms must keep clearly in mind what is being evolved and what evolves only by consequence. Notes on the simulation of evolution are offered in four sections: 1) the basic nature of evolution, 2) its practical simulation, 3) common philosophical errors, and 4) that which remains to be accomplished. Simulated evolutionary optimization is a mechanism of machine learning that can reasonably be expected to continue to grow in importance and practical benefit. As the availability of massively parallel processors increases, the value of simulated evolutionary techniques will become increasingly apparent, if for no other reason than the natural match between the technique and the emerging technology. The method has been repeatedly demonstrated to successfully find points of global optimality when other methods fail, often astonishingly quickly. Specific rules have become apparent and are easily stated.
A Maximum NEC Criterion for Compton Collimation to Accurately Identify True Coincidences in PET (2011)

In this work, we propose a new method to increase the accuracy of identifying true coincidence events for positron emission tomography (PET). This approach requires 3-D detectors with the ability to position each photon interaction in multi-interaction photon events. When multiple interactions occur in the detector, the incident direction of the photon can be estimated using the Compton scatter kinematics (Compton Collimation). If the difference between the estimated incident direction of the photon relative to a second, coincident photon lies within a certain angular range around colinearity, the line of response between the two photons is identified as a true coincidence and used for image reconstruction. We present an algorithm for choosing the incident photon direction window threshold that maximizes the noise equivalent counts of the PET system. For simulated data, the direction window removed 56%-67% of random coincidences while retaining > 94% of true coincidences from image reconstruction as well as accurately extracted 70% of true coincidences from multiple coincidences.
Orally Administered CpG Oligodeoxynucleotide Induces Production of CXC and CC Chemokines in the Gastric Mucosa and Suppresses Bacterial Colonization in a Mouse Model of<i>Helicobacter pylori</i>Infection (2003)

Bacterial DNA and unmethylated CpG oligodeoxynucleotides (CpG ODN) are known to be potent stimulators of the innate immune system in vitro and in vivo. We therefore investigated if oral administration of CpG ODN could enhance innate immunity in the gastric mucosa and control the extent of Helicobacter pylori infection in mice. Intragastric administration of a single dose of CpG ODN significantly increased local production of the CC chemokines macrophage inflammatory protein 1alpha (MIP-1alpha), MIP-1beta, and RANTES and the CXC chemokine gamma interferon-inducible protein 10 in the stomach and/or the small intestine. Importantly, intragastric administration of CpG ODN to mice with an already established H. pylori infection, in the absence of any coadministered antigen, was found to reduce the bacterial load in the stomach compared to the load in H. pylori-infected control mice, while similar administration of non-CpG ODN had no effect on the bacterial load. The reduction in the bacterial numbers in the stomachs of mice treated with CpG ODN was associated with enhanced infiltration of immune cells and increased RANTES production in the gastric mucosa compared to the infiltration of immune cells and RANTES production in H. pylori-infected control animals. These findings suggest that intragastric administration of CpG ODN without antigen codelivery may represent a valuable strategy for induction of innate immunity against H. pylori infection.
An ultrahigh stability, low-noise laser current driver with digital control (2008)

We present a low-noise, high modulation-bandwidth design for a laser current driver with excellent long-term stability. The driver improves upon the commonly used Hall-Libbrecht design. The current driver can be operated remotely by way of a microprocessing unit, which controls the current set point digitally. This allows precise repeatability and improved accuracy and stability. It also allows the driver to be placed near the laser for reduced noise and for lower phase lag when using the modulation input. We present the theory of operation for our driver in detail, and give a thorough characterization of its stability, noise, set-point accuracy and repeatability, temperature dependence, transient response, and modulation bandwidth.
Exploring the Use of Text Classification in the Legal Domain (2017)

In this paper, we investigate the application of text classification methods to support law professionals. We present several experiments applying machine learning techniques to predict with high accuracy the ruling of the French Supreme Court and the law area to which a case belongs to. We also investigate the influence of the time period in which a ruling was made on the form of the case description and the extent to which we need to mask information in a full case ruling to automatically obtain training and test data that resembles case descriptions. We developed a mean probability ensemble system combining the output of multiple SVM classifiers. We report results of 98% average F1 score in predicting a case ruling, 96% F1 score for predicting the law area of a case, and 87.07% F1 score on estimating the date of a ruling.
Back-propagation network and its configuration for blood vessel detection in angiograms (1995)

A neural-network classifier for detecting vascular structures in angiograms was developed. The classifier consisted of a multilayer feedforward network window in which the center pixel was classified using gray-scale information within the window. The network was trained by using the backpropagation algorithm with the momentum term. Based on this image segmentation problem, the effect of changing network configuration on the classification performance was also characterized. Factors including topology, rate parameters, training sample set, and initial weights were systematically analyzed. The training set consisted of 75 selected points from a 256x256 digitized cineangiogram. While different network topologies showed no significant effect on performance, both the learning process and the classification performance were sensitive to the rate parameters. In a comparative study, the network demonstrated its superiority in classification performance. It was also shown that the trained neural-network classifier was equivalent to a generalized matched filter with a nonlinear decision tree.