gebhart/patrepeval huggingface dataset:
Instructive influences of phagocytic clearance of dying cells on neutrophil extracellular trap generation (2014)

Coordinated programmes of resolution are thought to initiate early after an inflammatory response begins, actively terminating leucocyte recruitment, allowing their demise via apoptosis and their clearance by phagocytosis. In this review we describe an event that could be implicated in the resolution of inflammation, i.e. the establishment of a refractory state in human neutrophils that had phagocytosed apoptotic cells. Adherent neutrophils challenged with apoptotic cells generate neutrophil extracellular traps (NETs), filaments of decondensed chromatin decorated with bioactive molecules that are involved in the capture of various microbes and in persistent sterile inflammation. In contrast, neutrophils that had previously phagocytosed apoptotic cells lose their capacity to up-regulate β2 integrins and to respond to activating stimuli that induce NET generation, such as interleukin (IL)-8. A defective regulation of NET generation might contribute to the persistent inflammation and tissue injury in diseases in which the clearance of apoptotic cells is jeopardized, including systemic lupus erythematosus and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis.
Elimination of bicarbonate interference in the binding of U(VI) in mill‐waters to freeze‐dried chlorella vulgaris (1986)

Freeze-dried preparations of Chlorella vulgaris will accumulate U(VI) from alkaline, bicarbonate-containing waters collected from uranium mill process streams, provided that the pH is pre-adjusted to between 4.0 and 6.0. Bicarbonate ion complexes the uranyl ion in these waters and seriously interferes with the binding of U(VI) to the algal cells at pH values above 6.0. No binding of U(VI) to the algae occurred at the natural pH of 8.0 when Chlorella vulgaris was suspended in untreated mill-waters containing up to 2.5 x 10-4M U(VI). However, when the pH of these waters was lowered from 8.0 to near 5.0, with nitric acid, nearly quantitative binding of U(VI) to the alga was achieved. Binding is rapid and largely unaffected by ions including Na', CI-, NOT, -OAc, and SO:-. Our results indicate that provided steps are taken to eliminate bicarbonate interference, such as adjustment of the pH to near 5.0, dried algal biomass could prove useful for the removal and recovery of U(VI) from high carbonatecontaining waters.
Behandlung des Lupus mit dem Friedmannschen Tuberkulose-Heilmittel (1914)

Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
Applied Matrix Models: A Second Course in Linear Algebra with Computer Applications (1985)

STATIC AND STEADY-STATE MODELS: Systems with a Unique Solution Systems with Many Solutions Overdetermined Systems DYNAMIC MODELS: Discrete Time System Evolution Continuous Time System Evolution Index.
Analysis of field tests with an improved hydraulic vibrator (2009)

Vibroseis is a key source in land seismic exploration and has been undergoing many initiatives to increase both productivity and seismic data quality. Most of these innovations have dealt with the signals used to generate the Vibroseis sweep and techniques for simultaneous acquisition. This paper deals with physical modifications to the Vibrator itself designed to enhance performance at both the low and high ends of the frequency spectrum and also attempt to provide a more accurate measure of the ground force from the weighted sum. Vibrators using the original physical platform and two variants with different physical modifications were tested at a site with both downhole sensors and a 2D line of 3C sensors. One Vibrator used a relatively simple modification to the hydraulic system while another Vibrator also used a new heavier reaction mass and stiffer baseplate assembly. Analysis of the test results indicate that the hydraulic modifications alone improved signal level below 10Hz while the addition of the new reaction mass and baseplate assembly progressively improved the Vibrator performance from approximately 50Hz up to approximately 160Hz where other limits in the Vibrator system arise. Additionally the downhole spectrum from the new reaction mass and baseplate assembly displays a much improved match to the weighted sum, indicating that this measurement is more in line with the source signature.
A hybrid positron scanner (1970)

A hybrid positron scanner, which combines the simplicity of a mechanical scanner with the increased sensitivity of a large area array, has been designed utilizing nine crystal pairs and 25 coincidence circuits. This technique has the advantage over single-pair positron systems in that greatly increased source activity may be viewed. The instrument functions reliably in clinical studies and has proven useful in supplying data for computer studies of radioisotope scan data processing. Valuable experience with multi-detector systems and fast timing techniques has been gained.
Glossary of terms for thoracic radiology: recommendations of the Nomenclature Committee of the Fleischner Society (1984)

Glossary of terms for thoracic radiology: recommendations of the Nomenclature Committee of the Fleischner SocietyWJ TuddenhamAudio Available | Share
New Thiazolothiazole Copolymer Semiconductors for Highly Efficient Solar Cells (2011)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTNew Thiazolothiazole Copolymer Semiconductors for Highly Efficient Solar CellsSelvam Subramaniyan, Hao Xin, Felix Sunjoo Kim, and Samson A. Jenekhe*View Author Information Department of Chemical Engineering and Department of Chemistry, University of Washington, Seattle, Washington 98195-1750, United StatesE-mail: [email protected]Cite this: Macromolecules 2011, 44, 16, 6245–6248Publication Date (Web):July 25, 2011Publication History Received8 May 2011Revised15 July 2011Published online25 July 2011Published inissue 23 August 2011https://pubs.acs.org/doi/10.1021/ma201054ahttps://doi.org/10.1021/ma201054arapid-communicationACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views4472Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Copolymers,Mobility,Polymers,Solar cells,Thin films Get e-Alerts
40 MHz IF 1 MHz Bandwidth Two-Path Bandpass ΣΔ Modulator With 72 dB DR Consuming 16 mW (2008)

A bandpass modulator with two time-interleaved second-order modulators and cross-coupled paths is described. Split zeros around the 40 MHz IF provide a signal band of 1 MHz with 72 DR and 65.1 dB peak SNR. The circuit, integrated in a 0.18 CMOS technology, uses a 60 MHz clock per channel. Experimental results show that the in-band region is not affected by tones caused by mismatches and that a two-tones input causes an IMD signal of 68 . The power consumption is 16 mW with 1.8 V supply.
A 14-nm 0.14-ps<sub>rms</sub>Fractional-N Digital PLL With a 0.2-ps Resolution ADC-Assisted Coarse/Fine-Conversion Chopping TDC and TDC Nonlinearity Calibration (2017)

A digital fractional-N phase-locked loop (PLL) is presented. It achieves 137- and 142-fs rms jitter integrating from 10 kHz to 10 MHz and from 1 kHz to 10 MHz, respectively. With a frequency multiplication ratio of 207.0019231 [digitally controlled oscillator (DCO) frequency is 50 kHz away from an integer multiple of the 26-MHz reference clock], a −78.6-dBc fractional spur is achieved for an output clock that runs at half of the DCO frequency. Time-to-digital converter (TDC) chopping technique, TDC fine conversion through successive approximation register analog-to-digital converters (SARADCs), and TDC nonlinearity calibration improve integrated phase noise and fractional spurs. This design meets the performance requirement of the 256-QAM <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$4 \times 4$ </tex-math></inline-formula> MIMO LTE standard in 5-GHz ISM band and also the 5G cellular 64-QAM standard in 28-GHz band. This work, implemented in a 14-nm fin-shaped field effect transistor (FinFET) CMOS process, is integrated to a cellular RF integrated circuit supporting advanced carrier aggregation operation. This PLL draws 13.4 mW and occupies 0.257 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
The influence of key determinants on consumers' choice in tourism destination (2015)

This study aims at developing a model that explains the effect of different stimuli types (ST) (i.e. online reviews and advertising) on a tourist’s intention to visit (ITV) a new destination. Two separate studies were conducted to establish and validate the model that consists of stimulus mediators (SM): destination trust (DT) and interest (DI). 113 surveys were obtained in study 1 which focused on the effect of the different stimuli types. Study 2 used the Elaboration Likelihood Model (ELM) to explore how advertising could persuade consumers to make purchasing decisions and how tourists could be persuaded to visit attraction sites. 146 surveys were obtained in study 2. Structured equation model (SEM) technique was adopted in the data analysis. The result of the first study showed that advertising has a stronger effect than positive online reviews. The second study showed that peripheral route of elaborate likelihood model has a stronger effect than central route in the context of tourism. That is, peripheral route that could generate a strong spontaneous impact by providing a vivid portrait of what a tourist would experience through an image cue.
[Screening of specifically expressed genes in amphioxus neurula by construction of a subtractive cDNA library]. (2010)

SSH is an effective method for searching differentially expressed genes. The subtractive cDNA library we generated provides a tool for further study of regulatory mechanisms of amphioxus early embryonic development.
Implications for leaflet behaviour in heavily calcified patient-specific aortic roots : simulation of transcatheter aortic valve implantation (2015)

As life expectancy increases, there are more and more cases of age-related disease presenting to medical attention. Aortic stenosis (AS) is a common age-related heart condition in which there is a thickening and distortion of the valve leaflets together with calcium deposition in the aortic root and valve. Surgical valve replacement (SVR) of the calcified valve is the current default treatment for AS. However, due to the invasive nature of the procedure, a large population of patients are deemed too high risk to undergo SVR. Transcatheter aortic valve implantation (TAVI) was developed as a percutaneous alternative to SVR.<br/><br/>TAVI is a purely mechanical process beyond the initial positioning of the device, that is, there is no decision making. As a result it can be computationally modelled using finite element analysis (FEA). This thesis describes how FEA has been used to analyse the stresses within the prosthetic leaflets during and post-deployment. Further, the application of patient-specific deployment simulation for predicting adverse effects post TAVI was explored.<br/><br/>FEA simulation of TAVI deployment is challenging as a realistic aortic root model must be developed. This was accomplished by extracting data from patient specific medical images. The TAVI device itself, in particular the leaflets, are subjected to elevated stresses and deformation during deployment. Creating an FEA model robust enough to withstand the deployment process was achieved by modelling the leaflets in a planar orientation, then using a preliminary simulation to manipulate the leaflets into a functional position while maintaining a highly regular mesh.<br/><br/>The key findings in this thesis concern device orientation and how it influences the operating stress of the valve. Sub-optimal device orientation can result in an average stress increase of 25%, which could potentially reduce the lifespan of the device. Patient-specific deployment simulations were also shown to have application outside of device orientation assessment as regions of potential paravalvular aortic regurgitation were identifiable.
ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors (2015)

ARID1A has been identified as one of the most frequently mutated genes across human cancers. Our data suggest that clinical utility of PARP inhibitors might be extended beyond patients with BRCA mutations to a larger group of patients with ARID1A-mutant tumors, which may exhibit therapeutic vulnerability to PARP inhibitors.
Determination of the Solubility Parameters of Biodiesel from Vegetable Oils (2013)

The fatty acid methyl esters of vegetable oils and animal fats, more commonly known as biodiesel, represent a renewable, biodegradable, noninflammable, and low toxicity alternative to diesel. In this study, the Hansen solubility parameters (HSPs) and the interaction radius of the solute sphere (R0) were determined for the biodiesel derived from soybean oil, coconut oil, palm oil, and castor oil, using 45 solvents and solvent mixtures. The values for the HSPs and R0 obtained for the different biodiesels were soybean (15.03, 3.69, 8.92, and 11.33; MPa(1/2)); coconut (15.12, 3.99, 9.25, and 10.92; MPa(1/2)); palm (15.43, 5.28, 6.61, and 10.54; MPa(1/2)); and castor (16.10, 6.72, 9.11, and 11.78; MPa(1/2)). The HSPs of four biofuels were also determined using the average values of the fatty esters of each oil, calculated using group contribution. Subsequently, the solubilities of the biofuels were predicted using the van Krevelen–Hoftyzer, Greenhalgh, and Bagley approaches.
Nonvolatile Polymer Memory with Nanoconfinement of Ferroelectric Crystals (2010)

We demonstrate significantly improved performance of a nonvolatile polymeric ferroelectric field effect transistor (FeFET) memory using nanoscopic confinement of poly(vinylidene fluoride-co-trifluoroethylene) (PVDF-TrFE) within self-assembled organosilicate (OS) lamellae. Periodic OS lamellae with 30 nm in width and 50 nm in periodicity were templated using block copolymer self-assembly. Confined crystallization of PVDF-TrFE not only significantly reduces gate leakage current but also facilitates ferroelectric polarization switching. These benefits are due to the elimination of structural defects and the development of an effective PVDF-TrFE crystal orientation through nanoconfinement. A bottom gate FeFET fabricated using a single-crystalline triisopropylsilylethynyl pentacene channel and PVDF-TrFE/OS hybrid gate insulator shows characteristic source-drain current hysteresis that is fully saturated at a programming voltage of ±8 V with an ON/OFF current ratio and a data retention time of approximately 10(2) and 2 h, respectively.
Electrophile-Integrating Smiles Rearrangement Provides Previously Inaccessible C4′-<i>O</i>-Alkyl Heptamethine Cyanine Fluorophores (2015)

New synthetic methods to rapidly access useful fluorophores are needed to advance modern molecular imaging techniques. A new variant of the classical Smiles rearrangement is reported that enables the efficient synthesis of previously inaccessible C4'-O-alkyl heptamethine cyanines. The key reaction involves N- to O-transposition with selective electrophile incorporation on nitrogen. A representative fluorophore exhibits excellent resistance to thiol nucleophiles, undergoes productive bioconjugation, and can be used in near-IR fluorescence imaging applications.
Understanding College Students’ Thought Toward Social Events by Qualitative Meta-Synthesis Technologies (2011)

It is necessary to consider community opinions about social events and respond with proper actions. Support is needed to acquire a basic or rough idea of community opinions quickly. In this paper, the authors show how to elicit main points from community opinions with a simple word association test on college students about the highlighted social events in China in 2010. Two supporting technologies for qualitative meta-synthesis CorMap and iView are applied to analyze the opinions. Unlike basic descriptive statistical figures, CorMap/iView help identify the structures of opinions, which show the primary concerns of students or features of events, as a simple way to acquire a rough synthesis of public concerns rapidly.
Processing and performance of gold MCMs (1993)

The use of gold metallization in multichip modules (MCMs) has been investigated for the purpose of achieving simplified processing and high reliability. A process has been developed for producing multilayered, gold metallization thin film MCM (MCM-D) structures which reduces the number of processing steps compared to copper metallization. Multilayered gold-polymer and gold-SiO/sub 2/ test devices have been fabricated to evaluate the electrical and mechanical properties of the structures. The adhesion of a variety of dielectrics has been achieved by blanket coverage of the noble metal with a single step adhesion layer. The processing, performance, adhesion layer, and cost of gold MCM-D structures on silicon substrates have been analyzed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Chemistry of Taxol and Related Taxoids (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Portable Laser Ablation Sampling Device for Elemental Fingerprinting of Objects Outside the Laboratory with Laser Ablation Inductively Coupled Plasma Mass Spectrometry (2012)

Laser ablation-inductively coupled plasma mass spectrometry (LA-ICPMS) is a powerful method for elemental fingerprinting of solid samples in a quasi-nondestructive manner. In order to extend the field of application to objects outside the laboratory, a portable laser ablation sampling device was assembled using a diode pumped solid state laser and fiber-optics. The ablated materials were sampled on membrane filters and subsequently quantified by means of LA-ICPMS. The analytical performance of this approach was investigated for glass and gold reference materials. Accuracies of better than 20% were reached for most elements and typical limits of detection were found to be in the range of 0.01-1 μg/g. In summary, this approach combines spatially resolved sampling with the detection power of ICPMS and enables elemental fingerprinting of objects which cannot be transferred to the laboratory, e.g., archeological artifacts in museums.
Concurrency control of bulk access transactions on shared nothing parallel database machines (2002)

New concurrency control schemes are proposed for bulk access transactions (BATs) on shared-nothing database machines. A BAT is a transaction accessing a large bulk of data, such as a transaction updating a whole file. BATs are used for batch jobs in database services, and many BATs should be finished in a short time. Thus it is necessary to execute BATs concurrently on a database machine. When scheduling BATs, the performance is degraded by very high contention of both data and resources. Therefore, the strategy for scheduling BATs is to reduce the contention as much as possible. A weighted transaction precedence graph (WTPG) and two schedulers using it are proposed. A WTPG is used to estimate the degree of contention in a serializable schedule. Using a WTPG, the proposed schedulers reduced the contention by optimization. In the simulation, both schedulers achieve from 1.2 to 1.8 times higher throughput than atomic static lock and two-phase lock.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Microwave Techniques for the Measurement of the Dielectric Constant of Fibers and Films of High Polymers (1950)

A resonant cavity method is described for the determination of the dielectric constant of polymeric solids in the form of fibers, films, and thin cylinders. Methods for investigating electrical anisotropy are outlined. In the case of fibers, for the electric field parallel to the fiber axis, the dielectric constant is determined directly. For the electric field perpendicular to the fiber axis, the problem arises of calculating the dielectric constant of the fiber from that of an air-fiber mixture. For the latter purpose the Lichtenecker equation was found to be applicable. Illustrative measurements of the dielectric constant of wool, Nylon, and Cellophane are presented and discussed briefly.
The identification of salicylates as normal constituents of serum: a link between diet and health? (1998)

Salicylic acid, 2,3-DHBA, and 2,5-DHBA possess anti-inflammatory properties. The finding that these compounds are present as normal constituents of serum, possibly arising from diet, raises important questions as to their role in the promotion of health.