gebhart/patrepeval huggingface dataset:
Variational Autoencoded Compositional Pattern Generative Adversarial Network for Handwritten Super Resolution Image Generation (2018)

Since generative adversarial training has been decleared as one of the most exciting topics of the last 10 years by the pioneers, many researchers have focused on the Generative Adversarial Network (GAN) in their studies. On the otherhand, Variational Autoencoders (VAE) had gain autoencoders' popularity back. Due to some restrictions of GAN models and their lack of inference mechanism, hybrid models of GAN and VAE have emerged for image generation problem in nowadays. With the influence of these views and improvements, we have focused on addressing not only generating synthetic handwritten images but also their high-resolution version. For these tasks, Compositional Pattern Producing Networks (CPPN), VAE and GAN models are combined inspired by an existing model with some modification of its objective function. With this model, the idea behind the inspired study for generating high-resolution images are combined with the feature-wise reconstruction objective of a VAE/GAN hybrid model instead of pixel-like reconstruction approach of traditional VAE. For evaluating the model efficiency, our VAE/CPGAN model is compared with its basis models (GAN, VAE and VAE/GAN) and inspired model accoording to inception score. In this study, it is clearly seen that the proposed model is able to converge much faster than compared models for modeling the underlying distribution of handwritten image data.
Measurement errors in pattern recognition (1980)

The effect of measurement errors on the performance of the pattern classifier is studied. It is shown that measurement errors affect the optimality of the decision rule, and can result in higher classification error probability. The results derived in the paper are applied to the problem of quality control of gas meters. It is shown that, to maintain the same quality level of lots of 300 meters, the test sample set size had to be increased from 100 to 160 meters.
16,16-dimethyl prostaglandin E2 modulation of endothelial monolayer paracellular barrier function (1996)

Prostaglandins prevent gastrointestinal mucosal injury and promote healing following mucosal injury by various noxious agents. Preservation or repair of microvascular function appears to be crucial in these processes. The processes involved in prostaglandin-mediated repair and preservation of endothelial function are unclear. In the present study, we investigated the role of prostaglandins on endothelial paracellular barrier function using the filter-grown bovine aortic endothelial cell monolayers. Endothelial paracellular barrier function as assessed using a paracellular marker, mannitol. Prostaglandin analogs 16,16-dimethyl prostaglandin E2 (DMPGE2) and prostaglandin I2 (PGI2) caused an enhancement of endothelial monolayer paracellular barrier function as evidenced by a dose-dependent decrease in endothelial paracellular permeability. DMPGE2 induced enhancement of endothelial paracellular barrier function correlated directly with increasing intracellular cAMP levels. Agents which increase intracellular cAMP levels at different stages of cAMP amplification cascade including phosphodiesterase inhibitor (3-isobutyl-1 methylxanthine [IBMX]), membrane permeable cAMP (8-bromo cAMP), and adenylate cyclase activators (isoproterenol and forskolin) also produced enhancement in endothelial paracellular barrier function. DMPGE2 enhancement of paracellular barrier function correlated with dense accumulation of actin microfilaments near the intercellular junctions. IBMX, isoproterenol, forskolin, and 8-bromo cAMP also produced similar changes in endothelial actin microfilaments. Cytochalasin B prevented the DMPGE2 enhancement of paracellular barrier function. Indomethacin (INDO), a cyclooxygenase inhibitor, caused a dose-dependent increase in endothelial paracellular permeability. Pharmacologic doses of INDO resulted in condensation and disruption of actin microfilaments with formation of large paracellular openings or gaps between the adjacent cells. Pretreatment of endothelial monolayers with DMPGE2 prevented INDO-induced disturbance of actin microfilaments and paracellular barrier function. IBMX, isoproterenol, forskolin, and 8-bromo cAMP also prevented INDO-induced changes in actin microfilaments and paracellular barrier function. These findings indicate that DMPGE2 has a paracellular barrier enhancing effect on filter-grown endothelial monolayers. This effect appears to be mediated through intracellular cAMP and actin microfilaments.
실천공학교육 관련 : Pseudo-STEM에 기초한 미분방정식 교육 (2013)

본 연구에서는 학생중심의 수학 및 과학 교육법으로 화제가 되고 있는 STEM교육의 유래와 STEM 교육을 대학교육에 부분적으로 적용하고 있는 Hands-on교육과 일본대학의 수리공교육의 사례를 조사한다. STEM교육은 학생들이 기술과 공학의 문제에서 수학의 필요성을 자각하도록 하고, 더 나아가 수학교과에 대한 수동적 학습태도를 능동적으로 바꾸는데 적합한 방법으로 부상되고 있지만, S(과학), T(기술), E(공학), M(수학)의 물리적 융합이 아닌 화학적 융합으로써 현행 대학 교과과정에 바로 적용하기에는 다소 무리한 측면이 있다. 따라서 실제 프로젝트에서 고려되어야 하는 T와 E를 졸업작품에서 스스로 찾도록 하고, 이 자발적인 발견을 수학교과목과 연계하는 Pseudo-STEM교육법을 제안한다.
Association of polymorphisms in <i>GCKR</i> and <i>TRIB1</i> with nonalcoholic fatty liver disease and metabolic syndrome traits (2014)

In several genome-wide association studies, nonalcoholic fatty liver disease and alanine aminotransferase susceptibility variants have been identified in several genes, including LYPLAL1, ZP4, GCKR, HSD17B13, PALLD, PPP1R3B, FDFT1, TRIB1, COL13A1, CPN1, ERLIN1, CWF19L1, EFCAB4B, PZP, and NCAN. To investigate the relationship between these genes and nonalcoholic fatty liver disease in the Japanese population, we genotyped 540 patients and 1012 control subjects for 18 variations. We performed logistic regression analyses to characterize the association between the tested variations and nonalcoholic fatty liver disease. Metabolic syndrome and histological traits were also analyzed by linear regression. We also examined GCKR rs780094, TRIB1 rs2954021, and PNPLA3 rs738409 for epistatic effects. The A-allele of rs780094 in GCKR (P = 0.0024) and the A-allele of rs2954021 TRIB1 (P = 4.5×10⁻⁵) were significantly associated with nonalcoholic fatty liver disease. GCKR rs780094 was also associated with decreased plasma glucose, and increased triglycerides in the patient and control groups. GCKR rs780094 was also associated with an increased ratio of visceral to subcutaneous fat area in the patients with nonalcoholic fatty liver disease. Variations in GCKR, TRIB1, and PNPLA3 independently influenced nonalcoholic fatty liver disease and had no epistatic effects. Our data suggest variations in GCKR and TRIB1 are involved in the development of nonalcoholic fatty liver disease.
Observing the sun with a fully tunable Lyot-Ohman filter (1975)

We describe the properties of the Zeiss Universal Birefringent Filter and its optical and electronic interface with the Sacramento Peak Observatory'' vacuum telescope. The instrument permits observations of solar intensities, velocities, and/or magnetic fields in rapid succession in any Fraunhofer line in the 410-700-nm wavelength region with high spectral (0.004-0.013 nm) and high spatial (~1/3 sec of arc) resolution.
Analysis of Powders Containing Illicit Drugs Using Magnetic Levitation (2019)

Magneto-Archimedes levitation (MagLev) enables the separation of powdered mixtures of illicit drugs (cocaine, methamphetamine, heroin, fentanyl, and its analogues), adulterants, and diluents based on density, and allows the presumptive identification of individual components. Small samples (mass <50 mg), with low concentrations of illicit drugs, present a particular challenge to analysis for forensic chemists. The MagLev device, a cuvette containing a solution of paramagnetic gadolinium(III) chelate in a non-polar solvent, placed between two like-poles-facing NdFeB magnets, allowed separation of seven relevant compounds simultaneously. In particular, initial separation with MagLev, followed by characterization by FTIR-ATR, enabled identification of fentanyl in a sample of fentanyl-laced heroin (1.3 wt % fentanyl, 2.6 wt % heroin, and 96.1 wt % lactose). MagLev allows identification of unknown powders in mixtures and enables confirmatory identification based on structure-specific techniques.
Behavioral method for the treatment of idiopathic scoliosis. (1985)

Idiopathic scoliosis was treated by an automated portable posture-training device that incorporated precise behavioral principles and enabled therapeutic training to be given in the patients' normal environment throughout the entire day. Twenty-one patient-years of training were completed with a group of 12 adolescent girls selected as being imminently likely to require a brace because of the way their spinal curves had been progressing. As an alternative to conventional brace therapy, patients found the posture-training device considerably less physically restraining and more cosmetically acceptable. Most patients wore it 23 hr per day for at least 1 year and adapted well to the constant physical and psychological presence of the instrument. For 10 patients, the outcome was entirely successful; they were discharged from this pilot study as satisfactorily corrected. Progression of the scoliotic curve was arrested; in fact, there was an average slight improvement in the Cobb angle (a measure of spinal curvature) as measured by x-ray radiography.
Single Isomer of Indene-C<sub>70</sub> Bisadduct—Isolation and Performance in Bulk Heterojunction Solar Cells (2014)

Indene-C70 bisadduct (IC70BA) is a high performance electron acceptor material consisting of a mixture of regioisomers. A single isomer of the IC70BA was isolated by careful chromatographic separation. The structure of this isomer was confirmed by various analytical techniques including single crystal X-ray analysis. The isomer showed superior performance to other isomer mixtures of IC70BA in bulk heterojunction solar cells using poly(3-hexylthiophene) as the donor material.
Automatic identification of cardiac activations in the multi-channel intracardiac ECGs (2006)

A novel algorithm is presented in this paper, which can precisely identify the cardiac activations (e.g., A, V, H waves) in the multi-channel intracardiac electrogram (IECG) signals. The aim of this work is to achieve an automatic analysis during the electrophysiological (EP) study. It saves an amount of the time for the physicians compared with manual work, especially for the long-duration diagnosis or operation. The development of the algorithm complies with the various stimulation protocols in the EP lab. The effective digital signal processing techniques and the proper application of the relationship between the surface ECG (SECG) and intracardiac ECG enable the algorithm to achieve the satisfied sensitivity. Finally, 11 patients' data including more than 6000 meaningful cardiac activations are randomly collected from an EP (electrophysiology) lab to evaluate the algorithm. A comparison is made between the manual annotation of the physicians and the result of the algorithm. The sensitivity of the V, A, H wave detection reaches 98.99%, 96.64%, and 97.31% respectively. (4 pages)
Zinc potentiates the antibacterial effects of histidine‐rich peptides against <i>Enterococcus faecalis</i> (2006)

Antimicrobial peptides are effector molecules of the innate immune system. We have recently shown that peptides containing multiples of the heparin-binding Cardin and Weintraub motifs AKKARA and ARKKAAKA exert antimicrobial activities. Here, we show that replacement of lysine and arginine in these motifs by histidine abrogates the antibacterial effects of these peptides. Antibacterial activity of the histidine-rich peptides against the Gram-positive bacterium Enterococcus faecalis was restored by the addition of Zn2+. Fluorescence microscopy experiments showed that Zn2+ enabled binding of the histidine-rich peptides to Enterococcus faecalis bacteria. Similar Zn2+-dependent antibacterial activities were shown for histatin 5 as well as histidine-containing peptides derived from the Zn2+- and heparin-binding domain 5 of human kininogen. Thus, the results demonstrate a previously undisclosed Zn2+-dependent antibacterial activity of kininogen-derived peptides and indicate an important role for Zn2+ in regulating the antimicrobial activities of histidine-rich peptides.
Autosomal Dominant Nocturnal Frontal Lobe Epilepsy in a Spanish Family With a Ser252Phe Mutation in the CHRNA4 Gene (1999)

These data confirm the clinical homogeneity in the phenotypic expression of autosomal dominant nocturnal frontal lobe epilepsy caused by mutation in the CHRNA4 gene, and the pathogenic role of the Ser252Phe mutation in this disorder.
<i>CDKN1C</i> (<i>p57</i><sup><i>Kip2</i></sup>) analysis in Beckwith–Wiedemann syndrome (BWS) patients: Genotype–phenotype correlations, novel mutations, and polymorphisms (2010)

Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome characterized by macroglossia, macrosomia, and abdominal wall defects. It is a multigenic disorder caused in most patients by alterations in growth regulatory genes. A small number of individuals with BWS (5-10%) have mutations in CDKN1C, a cyclin-dependent kinase inhibitor of G1 cyclin complexes that functions as a negative regulator of cellular growth and proliferation. Here, we report on eight patients with BWS and CDKN1C mutations and review previous reported cases. We analyzed 72 patients (50 BWS, 17 with isolated hemihyperplasia (IH), three with omphalocele, and two with macroglossia) for CDKN1C defects with the aim to search for new mutations and to define genotype-phenotype correlations. Our findings suggest that BWS patients with CDKN1C mutations have a different pattern of clinical malformations than those with other molecular defects. Polydactyly, genital abnormalities, extra nipple, and cleft palate are more frequently observed in BWS with mutations in CDKN1C. The clinical observation of these malformations may help to decide which genetic characterization should be undertaken (i.e., CDKN1C screening), thus optimizing the laboratory evaluation for BWS.
MelNet: A Generative Model for Audio in the Frequency Domain (2019)

Capturing high-level structure in audio waveforms is challenging because a single second of audio spans tens of thousands of timesteps. While long-range dependencies are difficult to model directly in the time domain, we show that they can be more tractably modelled in two-dimensional time-frequency representations such as spectrograms. By leveraging this representational advantage, in conjunction with a highly expressive probabilistic model and a multiscale generation procedure, we design a model capable of generating high-fidelity audio samples which capture structure at timescales that time-domain models have yet to achieve. We apply our model to a variety of audio generation tasks, including unconditional speech generation, music generation, and text-to-speech synthesis---showing improvements over previous approaches in both density estimates and human judgments.
FOAM FRACTIONATION (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFOAM FRACTIONATIONC. A. Brunner and D. G. StephanCite this: Ind. Eng. Chem. 1965, 57, 5, 40–48Publication Date (Print):May 1, 1965Publication History Published online1 May 2002Published inissue 1 May 1965https://pubs.acs.org/doi/10.1021/ie50665a008https://doi.org/10.1021/ie50665a008research-articleACS PublicationsRequest reuse permissionsArticle Views328Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Scatter‐glare corrections in quantitative dual‐energy fluoroscopy (1988)

Previous attempts to use time subtraction intravenous digital subtraction angiography for ventricular imaging have been hampered by artifacts due to cardiac and respiratory motion. We have previously reported a motion-immune dual-energy technique in which kVp is switched between 60 and 120, at 300-500 mA, 30 times/s. In order to quantitate parameters such as ejection fraction and left ventricular volume, it is necessary to correct for scatter and veiling glare (SVG), which are the major sources of nonlinearities in videodensitometric digital subtraction angiography (DSA). In this report, a convolution filtering method has been investigated to estimate SVG in DSA images. In the first step, a grey level transformation of the detected image is utilized to get an estimated SVG image. In the second step this image is convolved to produce an image with appropriate spatial frequency content. Estimates of SVG in several Humanoid chest phantom images were obtained using Gaussian convolution kernels with a full width at half-maximum (FWHM) of 51-125 pixels. The root-mean-square (rms) percentage error of these estimates was obtained by comparison with direct SVG measurement. A convolution kernel with a FWHM of 75 pixels in each dimension applied to 16 Humanoid phantom images with various projections, thicknesses, and beam energies resulted in an average rms percentage error of 9.7% in the SVG estimate, for the 16 cases studied. The SVG estimation consisting of grey scale-to-SVG fraction lookup table (LUT) is made based on previous measurements. The x-ray settings required for each patient are utilized to alter the LUT in order to account for patient thickness variations.(ABSTRACT TRUNCATED AT 250 WORDS)
Structure of Gene Coding for the Fruit Body-Specific Hydrophobin Fbh1 of the Edible Basidiomycete Pleurotus ostreatus (2004)

Two fruit body-specific hydrophobins (Fbh1 and POH1) have been identified in two different strains of the edible basidiomycete Pleurotus ostreatus. Comparison of their nucleotide and amino acid sequences yielded similarity values (59% and 66%, respectively) smaller than those found for alleles of the same hydrophobin gene but higher than those found for different hydrophobin genes in P. ostreatus var. florida (Peñas et al 2002<$REFLINK> ———, Rust B, Larraya LM, Ramírez L, Pisabarro AG., 2002 Differentially regulated vegetative mycelium specific hydrophobins of the edible basidiomycete Pleurotus ostreatus. Appl Environ Microbiol 68:3891-3898 [Google Scholar]). In this paper, we have addressed the question of Fbh1 and POH1 allelism by studying the structure of the gene fbh1 and by a classical genetic analysis to compare it with that of POH1. The structure of both genes is similar, as revealed by the similarity of their promoters and leader peptide sequences and by the conserved position of their introns. Furthermore, the allelism analysis revealed that both genes segregated as alleles when present in the same hybrid. These results suggest an allelic condition for POH1 and fbh1 and stress the importance of the similarity of fbh1/POH1 promoter and leader sequences. Furthermore, we have identified various microsatellite-like regions in this gene that can be used for strain and species typing in the future.
Extracellular matrix modulates expression of growth factors and growth-factor receptors in liver-colonizing colon-cancer cell lines (1998)

Site-specific metastasis is determined by the extracellular matrix (ECM) of the colonized organ. We have shown that hepatocyte-derived ECM stimulated proliferation of colon-cancer cells via induction of autocrine growth factors and their receptors. The ECM component responsible was heparin proteoglycan. We therefore investigated the effect of exogenously added heparin on colon cell lines of varying liver-colonizing potential. The cells were grown on typical liver matrix components, such as fibronectin and collagens type I and IV. We assessed the effect of these matrix components on clonal growth, proliferation and expression of autocrine growth factors and their receptors. The clonal growth of the KM12 cells was not affected by heparin, while the other cell lines were inhibited by heparin. Cell proliferation in weakly metastatic KM12, but not in strongly metastatic KM12SM, was inhibited by heparin on plastic. Weakly metastatic LS174T, but not strongly metastatic LiM6, was inhibited by heparin on fibronectin. Expression of erb-B2 was also differently modulated by heparin in weakly metastatic vs. highly metastatic cells. In weakly metastatic cells, heparin reduced erb-B2 levels when cells were on plastic and fibronectin, while in strongly metastatic cells, erb-B2 was induced by heparin. In all 4 cell lines, mRNA for cripto was induced by heparin when the cells were grown on fibronectin. In KM12SM cells, amphiregulin was induced by heparin in cells on fibronectin and collagen IV. We show that soluble heparin, similar in its carbohydrate chemistry to liver heparin proteoglycan, regulates the growth of colon-cancer cells. This effect depends on other matrix components found in the liver and is mediated in part by EGF family members.
Self-Assembled Inverted Micelles Stabilize Ionic Liquid Domains in Supercritical CO<sub>2</sub> (2010)

Molecular aggregation is a complex phenomenon that is difficult to study in detail experimentally. Here, we elucidate the formation of ionic liquid-in-carbon dioxide (IL-in-CO(2)) microemulsions via a computer simulation technique that demonstrates the entire process of self-aggregation at the atomic level. Our study reveals direct evidence of the existence of stable IL droplets within a continuous CO(2) phase through amphiphilic surfactants. The microstructure of the nanodroplets matches very well with the small-angle neutron scattering data. A detailed investigation of the structural and energetic properties explains why guanidium acetate-based IL-in-CO(2) microemulsions showed a greater stability than imidazolium hexafluorophosphate-based microemulsions in recent spectroscopic experiments. In contrast to the existing hypothesis in literature, the study reveals that the stability of the microemulsions mainly pertains to the IL anion-headgroup interactions, while the cations play a secondary role. The detailed atomic level understanding provides a deeper insight that could help in designing new surfactants for improved IL uptake in CO(2).
Quantitative Size Exclusion Chromatography: Assessing New Developments (1990)

Abstract Methods of assessing new technology are achieving increased importance because rapid technological changes cause obsolescence of evaluations before they are completed. Users now must often evaluate the specific version of the new technology that they receive. Four major areas are used here to provide examples of assessment methods: high resolution columns, coupled concentration-molecular weight-differential viscometer detectors, flow rate monitoring using a thermal pulse flowmeter and determination of Mark-Houwink constants from polydisperse standards. Specific methods of assessment examined centre about error analysis and sensitivity analysis. Several of the methods use the conventional calibration curve. The idea of correction priority (i.e. thoroughly examining the most fundamental significant corrections first) is emphasized.