gebhart/patrepeval huggingface dataset:
Design and fabrication of low-cost reconfigurable microstrip antenna using photodiode as optical switching (2014)

Design, fabrication, and characterization prototype of reconfigurable dipole microstrip antenna using photodiode as optical switching have been conducted in the Laboratory for Optical and Microwave Physics Department Faculty of ITS. This paper presents a new reconfigurable antenna design using photodiode as optical switching. In order to be optical switching, photodiode must be illuminated by optical source. The optical source used is Infrared with power 8 mW. Antenna is fabricated in FR-4 substrate which has 1.6 mm thick and 4.8 relative permittivity value. The dimension of the substrate is 131 mm 21.5 mm 1.6 mm. The structure of antenna is Coplanar Stripline (CPS) dipole. Measurement is conducted in two state. First state is photodiodes unilluminated Infrared and the second state is illuminated. The measurement result indicate that if condition is not illuminated by Infrared (OFF-state) antenna has resonance frequency of 2010 MHz and 2120 MHz. At frequency 2010 MHz, S11 value -35.7 dB and bandwidth 57 MHz, meanwhile at frequency 2120 MHz, S11 value -17.3 dB and bandwidth 42 MHz. Then if photodiode was illuminated by infrared (ON-state), antenna work at frequency 2007 MHz with S11 value -41.8 dB and bandwidth 61 MHz and 2113 MHz with S11 value -19.4 and bandwidth 47 MHz. There was frequency shifting from 2010 MHz to 2007 MHz and 2120 MHz to 2113 MHz of 5 MHz. At ON state, S11 value also was shifting. There was 6.1 dB and 2.1 dB. Bandwidth at ON-state is wider than OFF state. Microstrip antenna with a reconfigurable optical switching photodiode has several advantages. The advantages are more easily fabricated and the cost is relatively cheaper than the other techniques of optical switching.
Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells (2017)

Fusaric acid (FA), a food-borne mycotoxin, is a potent divalent metal chelator. The human immune system is complex and susceptible to environmental insult however, the immunotoxity of FA remains unknown. We investigated the immunotoxicity of FA on human peripheral blood mononuclear cells (PBMCs) and Thp-1 cells. FA was cytotoxic to PBMCs (IC<sub>50</sub>-240.8 μg/ml) and Thp-1 (IC<sub>50</sub>-107.7 μg/ml) cells at 24 h. FA induced early apoptosis but significantly decreased caspase activity in PBMCs, a characteristic of paraptosis. In Thp-1 cells, FA induced apoptosis and increased caspase -9 and -3/7 activities. In PBMCs, FA maintained mitochondrial membrane potential and decreased protein expression of Bax whilst increasing expression of p-Bcl-2; FA induced oxidative stress and depleted ATP levels in both cell types. In Thp-1 cells, FA increased mitochondrial membrane depolarization and decreased p-Bcl-2 expression. In PBMCs, FA significantly up-regulated the MAPK protein expression of p-ERK and p-JNK but down-regulated p-p38 expression. In Thp-1 cells, FA up-regulated MAPK protein expression of p-ERK whilst p-JNK and p-p38 expression were down-regulated. In conclusion FA induced programmed cell death and altered MAPK signaling in healthy PBMCs and Thp-1 cells strongly suggesting a possible mechanism of FA induced immunotoxicity in vitro.
Pharmacokinetic Studies of the Fragrance Compound 1,8-Cineol in Humans during Inhalation (1996)

The present study was undertaken to investigate the pharmacokinetics of 1,8-cineol in human subjects during prolonged inhalation. The results showed that 1,8-cineol is well absorbed from breathing air, with a peak plasma concentration after approximately 18 min. The elimination of this fragrance compound from the blood is biphasic, with a mean distribution half-life of 6.7 min and an elimination half-life of 104.6 min.
SimTag: exploiting tag bits similarity to improve the reliability of the data caches (2010)

Though tag bits in the data caches are vulnerable to transient errors, few effort has been made to reduce their vulnerability. In this paper, we propose to exploit prevalent same tag bits to improve error protection capability of the tag bits in the data caches. When data are fetched from the main memory, it is checked if adjacent cache lines have the same tag bits as those of the data fetched. This similarity information is stored in the data caches as extra bits to be used later. When an error is detected in the tag bits, the similarity information is used to recover from the error in the tag bits. The proposed scheme has small area, energy, and performance overheads with error protection coverage of 97.9% on average. In contrast, the previously proposed In-Cache Replication scheme is shown to incur large performance and energy overheads.
Grundlagen der Bilddaten-Verarbeitung (1993)

Wie vieles in der Welt der Computer hat auch die Computergrafik eine besondere Ordnung, die eine automatische Organisation durch die Elektronik ermöglicht.
INTERCAPILLARY GLOMERULOSCLEROSIS (1939)

In 1936, Kimmelstiel and Wilson 1 reported the pathologic observations in a group of 8 cases of a peculiar renal lesion to which they gave the name intercapillary glomerulosclerosis. On reviewing the clinical records of the cases they found that the observations fell into a fairly well defined symptom complex, consisting of diabetes, albuminuria, hypertension, retinal vascular changes, a more or less well developed nephrotic syndrome and some degree of renal insufficiency. Anson, 2 in 1938, published a study of the kidneys in the last 900 autopsies at the Hospital of the Medical College of Virginia; he observed 6 cases which satisfied the pathologic criteria proposed by Kimmelstiel and Wilson. Clinically the same features were present as in those of the latter workers, except that the nephrotic syndrome was present in only 2 instances. Neither of these groups of cases was completely studied medically, since a number of the patients
A layered architecture for location-based services in wireless ad hoc networks (2003)

The design of a location services module (LSM) that provides a foundation for location-aware services is described. The architecture enhances application software development by providing a simple interface that hides details of the particular underlying location determination technologies. Functions for multiple technology switching, error estimation, location tracking, multiple technology fusion and cooperative location determination are defined. Several self-organizing protocols for cooperative location determination algorithms appropriate for wireless ad hoc networks are described. An example implementation of location-based services for a world wide web browser using an LSM is provided.
Strategies for the asymmetric functionalization of indoles: an update (2014)

During the past four years, the research of new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has had a fruitful and important growth. This research line continues to produce stunning arrays of enantioselective technologies either metal or organocatalyzed. Thus, an update of our previous review (Chem. Soc. Rev., 2010, 39, 4449-4465) has become necessary and this critical review documents the literature on this topic, until the end of 2013.
Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case control study (2007)

Our data suggest that prior exposure to fluoroquinolones and antipseudomonal penicillins are independent risk factors for the development of CRKp infections.
Selective Growth of Gallium Arsenide on Germanium Fins with Different Orientations formed on 10 degrees Offcut Germanium-on-Insulator Substrate (2012)

2012 International Conference on Solid State Devices and Materials,Selective Growth of Gallium Arsenide on Germanium Fins with Different Orientations formed on 10 degrees Offcut Germanium-on-Insulator Substrate
Chronic disease self-management and the liberation inherent in understanding the social construction of chronic disease (2024)

In 1979 I was handed a life sentence; the task of setting up a course within the Monash University Master of Environmental Science Degree in Systems Thinking and the Social Construction of Reality. Once I'd understood the terms of that sentence (it took some five years), my new understanding facilitated a new life within my immediate reality as a chronically ill person and of course in the wider dimensions of my life in general. And so began a radically different and much healthier relationship to my condition.
Tailoring the properties of polypropylene in the polymerization reactor using polymeric nucleating agents as prepolymers on the Ziegler–Natta catalyst granule (2016)

Nodular polypropylene from reactor granule technology for the production of a stiff and ductile material.
Electronic effects of sodium in epitaxial CuIn1−xGaxSe2 (1997)

Temperature dependent Hall effect measurements were made on Na-contaminated and uncontaminated epitaxial p-type CuIn1−xGaxSe2 films. Na was introduced by diffusion into as-deposited samples using both NaOH and Na2Se as sources. Na concentrations were measured using secondary ion mass spectroscopy by comparison to an implanted standard. Films contaminated with Na from either source were found to have much lower compensating donor densities than as-deposited films. Oxygen and other impurities were not found to be necessary to produce this effect although some changes with Se content were observed. These were independent of the Na effect.
Sparse pixel vectorization: an algorithm and its performance evaluation (1999)

Accurate and efficient vectorization of line drawings is essential for their higher level processing. We present a thinningless sparse pixel vectorization (SPV) algorithm. Rather than visiting all the points along the wire's black area, SPV sparsely visits selected medial axis points. The result is a crude polyline, which is refined through polygonal approximation by removing redundant points. Due to the sparseness of pixel examination and the use of a specialized data structure, SPV is both time efficient and accurate, as evaluated by our proposed performance evaluation criteria.
The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid ω-hydroxylase involved in suberin monomer biosynthesis (2008)

The lipophilic biopolyester suberin forms important boundaries to protect the plant from its surrounding environment or to separate different tissues within the plant. In roots, suberin can be found in the cell walls of the endodermis and the hypodermis or periderm. Apoplastic barriers composed of suberin accomplish the challenge to restrict water and nutrient loss and prevent the invasion of pathogens. Despite the physiological importance of suberin and the knowledge of the suberin composition of many plants, very little is known about its biosynthesis and the genes involved. Here, a detailed analysis of the Arabidopsis aliphatic suberin in roots at different developmental stages is presented. This study demonstrates some variability in suberin amount and composition along the root axis and indicates the importance of omega-hydroxylation for suberin biosynthesis. Using reverse genetics, the cytochrome P450 fatty acid omega-hydroxylase CYP86A1 (At5g58860) has been identified as a key enzyme for aliphatic root suberin biosynthesis in Arabidopsis. The corresponding horst mutants show a substantial reduction in omega-hydroxyacids with a chain length <C(20), demonstrating that CYP86A1 functions as a hydroxylase of root suberized tissue. Detailed expression studies revealed a strong root specificity and a localized expression in the root endodermis. Transgenic expression of CYP86A1 fused to GFP distributed CYP86A1 to the endoplasmic reticulum, indicating that suberin monomer biosynthesis takes place in this sub-cellular compartment before intermediates are exported in the apoplast.
Developments in Blast Furnace Gas Distribution Research (1979)

Experimental results on the measured pressure loss in uniform and layered packed beds of blast furnace raw materials are presented. The importance of the particle size and void fraction of the granular mixture in dictating the gas phase permeability is emphasised. The results of the work are used in a theoretical predictive model for gas flow through the blast furnace softening-melting zone.
Two distinct origins of a common BRCA1 mutation in breast-ovarian cancer families: a genetic study of 15 185delAG-mutation kindreds. (1996)

We screened 163 women from breast-ovarian cancer-prone families, as well as 178 individuals affected with breast and/or ovarian cancer but unselected for family history, for germ-line mutations in exon 2 of BRCA1, by SSCP analysis and direct sequencing. A total of 25 mutations were detected. Thirteen of 64 Jewish Ashkenazi women and 2 non-Jewish individuals were found to possess the 185delAG mutation. Haplotype data for all 15 individuals, with markers intragenic to BRCA1, suggest that the Jewish Ashkenazi individuals share a common ancestry that is distinct from the lineage shared by the other two women. These data provide the first evidence of two distinct lines of transmission for the 185delAG mutation, only one of which has its origins in the Jewish Ashkenazi population. Our screening also uncovered 10 affected individuals with an 11-bp deletion at nucleotide 188 of BRCA1 (188del11), 4 of whom are Ashkenazi Jews. This is only the third reported mutation detected within the Jewish Ashkenazi population and may represent the second most common alteration in BRCA1 found in Ashkenazi Jews in the United States. The observed overrepresentation of specific mutations within a subgroup of the general population may eventually contribute to the development of inexpensive and routine tests for BRCA1 mutations, as well as to the elucidation of other contributory factors (e.g., diet, environment, and chemical exposures) that may play a key role in cancer initiation and development. The implications of the mutational data, as well as the role that founder effect, demographic history, and penetrance play in the resulting observed phenomena, are discussed.
Towards a Chaotic Musical Instrument (1993)

The goal of this project is to produce a software musical instrument using chaotic processes as a sound synthesis method. Real-time control through MIDI note messages and continuous controllers is required. Early results are described, along with suggestions for continuing work.
Neuropsychological function in nonpsychotic unipolar major depression. (2001)

Nonhospitalized patients with a nonpsychotic unipolar major depressive disorder exhibited an overall neuropsychological deficit and they performed disproportionately worse in the two domains of selective attention and working memory. The neurobiological implications of the present results are in accordance with the hypothesis that there is a global-diffuse impairment of brain function with particular involvement of the frontal lobes in nonpsychotic unipolar major depressive disorder.
An Implementation of Service Composition for Enterprise Business Processes (2019)

The Microservice Architecture (MSA) is an advanced architecture with flexible technology selection, independent on-demand expansion, and high availability. It is one of the best solution for enterprise software systems to cope with cloud deployment. Moreover, Spring Cloud provides comprehensive technical support for microservice architecture; also, it is the best technical framework for implementing microservice architecture. The container technology represented by Dockers provides an independent and undisturbed deployment environment for microservice architecture. Based on the microservice architecture and lightweight container technology, this article propose an implementation idea for service composition.
Neuronal responses in cat primary auditory cortex to electrical cochlear stimulation. I. Intensity dependence of firing rate and response latency (1994)

1. Responses of neurons in primary auditory cortex (AI) of the barbiturate anesthetized adult cat were studied using cochlear stimulation with electrical and acoustic stimuli. Acoustic stimulation of the ear ipsilateral to the studied cortical hemisphere with brief biphasic clicks was compared with electrical stimulation of the contralateral cochlea with brief biphasic electrical pulses delivered via a feline cochlear prosthesis. The contralateral ear was deafened immediately before implantation of the cochlear prosthesis. The feline cochlear prosthesis consisted of four bipolar electrode pairs and was placed in the scala tympani. Two bipolar electrode conditions were used for stimulation: one near radial pair with electrode spacing of approximately 0.5 mm, and one longitudinal pair with electrode spacing of approximately 6 mm. 2. The firing rates obtained from single- and multiple-neuron recordings were measured as a function of stimulus intensity for single electrical and acoustic pulses. Resulting rate/level functions were characterized by a fast growing low-level segment and a more slowly growing, saturating, or decreasing high-level segment. The slopes of these two segments as well as the stimulus level and firing rate at the juncture of these two segments (the transition point) provide a complete characterization of the response magnitude behavior as a function of stimulus intensity. 3. The main characteristics of rate/level functions obtained with electrical and acoustic cochlear stimulation were quite similar. However, for any given neuron, differences in the primary growth behavior, such as monotonic or nonmonotonic growth, could be observed between the different stimulation modes. 4. Response latencies from single- and multiple-neuron recordings were obtained as a function of stimulus intensity for electrical and acoustic pulses. Resulting latency/level functions were characterized by a rapidly decreasing low-level segment and a more slowly decreasing high-level segment. The slopes of these two segments as well as the stimulus level and response latency at the juncture of these two segments (the transition point) provide a complete characterization of the response latency behavior as a function of stimulus intensity. Transition point levels for the rate/level function and the latency/level were nearly identical. 5. The characteristic latency behavior for each neuronal response was found to be very similar for acoustic and electrical stimulation. Correlation analysis revealed a close relationship between latency parameters of the two electrical stimulation conditions, a weaker relationship between the longitudinal electrical and the acoustic conditions, and the weakest relationship between the radial electrical and acoustic conditions. 6. Correlation analysis for rate and latency parameters revealed several relationships between these response aspects.(ABSTRACT TRUNCATED AT 400 WORDS)
How many signal peptides are there in bacteria? (2013)

Over the last 5 years proteogenomics (using mass spectroscopy to identify proteins predicted from genomic sequences) has emerged as a promising approach to the high-throughput identification of protein N-termini, which remains a problem in genome annotation. Comparison of the experimentally determined N-termini with those predicted by sequence analysis tools allows identification of the signal peptides and therefore conclusions on the cytoplasmic or extracytoplasmic (periplasmic or extracellular) localization of the respective proteins. We present here the results of a proteogenomic study of the signal peptides in Escherichia coli K-12 and compare its results with the available experimental data and predictions by such software tools as SignalP and Phobius. A single proteogenomics experiment recovered more than a third of all signal peptides that had been experimentally determined during the past three decades and confirmed at least 31 additional signal peptides, mostly in the known exported proteins, which had been previously predicted but not validated. The filtering of putative signal peptides for the peptide length and the presence of an eight-residue hydrophobic patch and a typical signal peptidase cleavage site proved sufficient to eliminate the false-positive hits. Surprisingly, the results of this proteogenomics study, as well as a re-analysis of the E. coli genome with the latest version of SignalP program, show that the fraction of proteins containing signal peptides is only about 10%, or half of previous estimates.
Multi-Modality Therapeutics with Potent Anti-Tumor Effects: Photochemical Internalization Enhances Delivery of the Fusion Toxin scFvMEL/rGel (2009)

This is a unique demonstration that a non-invasive multi-modality approach combining a recombinant, targeted therapeutic such as scFvMEL/rGel and PCI act in concert to provide potent in vivo efficacy without sacrificing selectivity or enhancing toxicity. The present DDS warrants further evaluation of its clinical potential.
Comparative RNA-Seq Analysis of Early-Infected Peach Leaves by the Invasive Phytopathogen Xanthomonas arboricola pv. pruni (2013)

Xanthomonas arboricola pv. pruni is a quarantine bacterial pathogen that threatens peach production by causing necrotic spots on leaves and fruits, thus with the potential of severely reducing yields. The current understanding of the host plant defense responses to the pathogen is very limited. Using whole transcriptome sequencing, differential gene expression was analyzed at two time points, 2 h and 12 h post inoculation (hpi), by comparing the inoculated samples to their respective controls. On the total of 19,781 known peach genes that were expressed in all time points and conditions, 34 and 263 were differentially expressed at 2 and 12 hpi, respectively. Of those, 82% and 40% were up-regulated, respectively; and 18% and 60% were down-regulated, respectively. The functional annotation based on gene ontology (GO) analysis highlighted that genes involved in metabolic process and response to stress were particularly represented at 2 hpi whereas at 12 hpi cellular and metabolic processes were the categories with the highest number of genes differentially expressed. Of particular interest among the differentially expressed genes identified were several pathogen-associated molecular pattern (PAMP) receptors, disease resistance genes including several RPM1-like and pathogenesis related thaumatin encoding genes. Other genes involved in photosynthesis, in cell wall reorganization, in hormone signaling pathways or encoding cytochrome were also differentially expressed. In addition, novel transcripts were identified, providing another basis for further characterization of plant defense-related genes. Overall, this study gives a first insight of the peach defense mechanisms during the very early stages of infection with a bacterial disease in the case of a compatible interaction.