gebhart/patrepeval huggingface dataset:
Experiences with Acetazolamid Therapy Applied in Our Clinic to Patients Suffering from Ménière's Disease for More than 8 Years (1966)

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Digital Phase Sampling for Microcomputer Implementation of Carrier Acquisition and Coherent Tracking (1980)

By sampling zero crossings at the Nyquist rate (i.e., the predetection bandwidth) the phase of a narrow-band signal may be extracted directly with respect to an arbitrary, stable reference. Analysis, simulation, and experimental results are presented validating this all-digital technique for acquisition and coherent tracking of a Doppler-shifted carrier at a low carrier/noise ratio and a large percentage bandwidth. The key advantage of this scheme for microcomputer-based implementation is that phase comparison is accomplished by arithmetic subtraction, without the coordinaterotation transformation which is necessary for conventional <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">I</tex> , <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> sampling. Also, the phase-sampling process is independent of the phase error, which exists only as a numerical representation in the digital tracking algorithm. The technique is applicable to Costas suppressed-carrier tracking and to BPSK bit synchronization and demodulation, by programming the appropriate digital algorithms.
Dominant recombination center in electron-irradiated 3<i>C</i> SiC (1996)

Deep level defects and their role in carrier recombination processes in electron-irradiated 3C SiC have been studied by photoluminescence (PL) and optically detected magnetic resonance (ODMR). An isotropic ODMR spectrum, with a g value of 2.0061±0.0002 and an effective electron spin S=1/2, is observed in irradiated 3C SiC films. From the spectral dependence studies of the ODMR signal, the defect is shown to be a deep level center related to a radiation-induced PL band with a zero-phonon line at 1.121 eV. Due to the competition between different carrier recombination channels, this ODMR spectrum can also be observed as a decrease of any other PL emissions from the sample, indicating its dominant role in recombination processes.
Solution Structure of LCI, a Novel Antimicrobial Peptide from <i>Bacillus subtilis</i> (2011)

LCI, a 47-residue cationic antimicrobial peptide (AMP) found in Bacillus subtilis, is one of the main effective components that have strong antimicrobial activity against Xanthomonas campestris pv Oryzea and Pseudomonas solanacearum PE1, etc. To provide insight into the activity of the peptide, we used nuclear magnetic resonance spectroscopy to determine the structure of recombinant LCI. The solution structure of LCI has a novel topology, containing a four-strand antiparallel β-sheet as the dominant secondary structure. It is the first structure of the LCI protein family. Different from any known β-structure AMPs, LCI contains no disulfide bridge or circular structure, suggesting that LCI is also a novel β-structure AMP.
Reducing traffic congestion in ZigBee networks: Experimental results (2013)

In this paper we propose and test, through experimentation on the field, a novel routing protocol for Zigbee networks. The proposed solution aims at reducing traffic congestion, causing delays, packets losses and unfair use of the energy resources of nodes in the network. The protocol exploits, at the network layer, the information related to medium access control losses, therefore collisions, to select the best path to reach the destination, accounting for both, connectivity and congestion on links. The protocol has been implemented on the MC1322x platform produced by Freescale and a comparison between the proposed protocol and Zigbee has been performed. Results demonstrate the significant improvement achieved in terms of packet loss rate and of nodes usage balance, the latter resulting in longer network lifetime.
Big Data Orchestration as a Service Network (2017)

This article argues that a big data network joint SDN, together with cloud and fog computing platforms, can build a service chain network. In SDN, the purpose is to reduce a large amount of redundant data and response time. We propose a novel Big Data Orchestration as a Service (BDOaaS) as the networking framework, which can dynamically orchestrate big data into services in SDN. In BDOaaS networking, the data center distributes software to all devices in the distributed network, which can orchestrate big data into services in the distributed network; the services- oriented network model is formed. Thus, the network load and response time is reduced. The BDOaaS framework and various components of BDOaaS as well as operation mechanisms are discussed in detail. Simulation results are presented to show the effectiveness of the proposed BDOaaS framework. In addition, we discuss a number of challenges in implementing the proposed framework in next generation networks.
Construction of a Pultruded Composite Structure: Case Study (2000)

In a recent research and development project a novel prototype pultruded composite structure was designed, fabricated, and tested. The bargelike, box-girder type structure measured approximately 24-ft long by 15-ft wide by 5-ft high (7.3 × 4.6 × 1.5 m). The structure was constructed from commercially available off-the-shelf pultruded structural profiles and panel sections. Tubular steel structural members and steel hardware were used to connect and join the different sections and subassemblies. The structure consisted of three 24-ft-long by 5-ft-wide by 5-ft-high (7.3 × 1.5 × 1.5 m) rectangular box-girder modular units and six 4-ft (1.2-m) wide modular deck panels. A design requirement was that the structure be capable of being transported by conventional, nonpermit trucking and be assembled at a remote site for subsequent testing. The structure was fabricated at a ship building and repair shop in Norfolk, Va., whose primary expertise was with conventional steel ship-structure fabrication methods and which had no prior experience with fabricating a large pultruded structural system. To fabricate and assemble the structure, a set of construction documents was produced. These included a set of written construction and assembly specifications, a set of detailed construction drawings, a detailed parts list, and a schedule. This case study details the construction process and provides a step-by-step explanation of how the engineering design team developed the construction documents for a relatively complex pultruded composite structure. Details of the design, analysis, and testing of the system are provided elsewhere.
A Comparison of Sucralfate and Prednisolone Enemas in the Treatment of Active Distal Ulcerative Colitis (1989)

Sucralfate is well established in the treatment of upper gastrointestinal inflammation and ulceration, and preliminary evidence suggests it may be of benefit in active colitis. We have therefore undertaken a clinical trial to compare enemas of sucralfate (4 g) and prednisolone metasulphobenzoate (20 mg) in the treatment of active distal ulcerative colitis. Forty-four patients were entered into a 4-week study. Two patients were withdrawn because of non-compliance, and five were unable to complete the study: two developed constipation (both allocated to sucralfate) and three were unable to retain the enemas (two prednisolone and one sucralfate). Intention-to-treat analysis showed significant within-treatment improvement in rectal bleeding, sigmoidoscopic grade, and histologic grade in the prednisolone-treated group, and in stool frequency, rectal bleeding, and sigmoidoscopic grade in the sucralfate-treated group. Between-treatment comparisons, however, showed greater resolution of rectal bleeding and more marked improvements in histologic grade in patients treated with prednisolone metasulphobenzoate enemas. Further studies using higher doses of sucralfate would be useful.
A flexible co-processing approach for SoC-FPGAs based on dynamic partial reconfiguration and bitstream relocation methods (2015)

Today's FPGAs merge the inherent demands on performance and flexibility more efficiently than ever before. Besides the integration of multi-core processors these SoC devices support dynamic partial reconfiguration of their fabric. Nevertheless, this technology is barely exploited in industrial projects. Major reasons for this position are a lack of design automation and missing abstraction layers. This paper addresses this issue and presents a co-processing framework taking advantage of dynamic reconfiguration while hiding the underlying complexity. At a low level, bitstream relocation methods are provided for Xilinx's 7 series devices, inherently leveraging the system's flexibility and resource utilization. The proposed framework finally provides a set of on-demand reconfigurable co-processing units to a SW-based processing system. This lightweight library based approach offers hardware acceleration for computationally intensive tasks by simple function calls as part of a software design.
S2Logger: End-to-End Data Tracking Mechanism for Cloud Data Provenance (2013)

The inability to effectively track data in cloud computing environments is becoming one of the top concerns for cloud stakeholders. This inability is due to two main reasons. Firstly, the lack of data tracking tools built for clouds. Secondly, current logging mechanisms are only designed from a system-centric perspective. There is a need for data-centric logging techniques which can trace data activities (e.g. file creation, edition, duplication, transfers, deletions, etc.) within and across all cloud servers. This will effectively enable full transparency and accountability for data movements in the cloud. In this paper, we introduce S2Logger, a data event logging mechanism which captures, analyses and visualizes data events in the cloud from the data point of view. By linking together atomic data events captured at both file and block level, the resulting sequence of data events depicts the cloud data provenance records throughout the data lifecycle. With this information, we can then detect critical data-related cloud security problems such as malicious actions, data leakages and data policy violations by analysing the data provenance. S2Logger also enables us to address the gaps and inadequacies of existing system-centric security tools.
Stable Isotope-Labeling Studies in Metabolomics: New Insights Into Structure and Dynamics of Metabolic Networks (2014)

The rapid emergence of metabolomics has enabled system-wide measurements of metabolites in various organisms. However, advances in the mechanistic understanding of metabolic networks remain limited, as most metabolomics studies cannot routinely provide accurate metabolite identification, absolute quantification and flux measurement. Stable isotope labeling offers opportunities to overcome these limitations. Here we describe some current approaches to stable isotope-labeled metabolomics and provide examples of the significant impact that these studies have had on our understanding of cellular metabolism. Furthermore, we discuss recently developed software solutions for the analysis of stable isotope-labeled metabolomics data and propose the bioinformatics solutions that will pave the way for the broader application and optimal interpretation of system-scale labeling studies in metabolomics.
Radical reactions of arenediazonium ions: An easy entry into the chemistry of the aryl radical (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRadical reactions of arenediazonium ions: An easy entry into the chemistry of the aryl radicalCarlo GalliCite this: Chem. Rev. 1988, 88, 5, 765–792Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/cr00087a004https://doi.org/10.1021/cr00087a004research-articleACS PublicationsRequest reuse permissionsArticle Views7881Altmetric-Citations676LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of Sodium Naproxen Eye Drops on Rabbit Ocular Inflammation Induced by Sodium Arachidonate (1991)

Sodium naproxen, a reversible competitive inhibitor of cyclooxygenase, is widely used as an anti-inflammatory agent in clinical practice. The purpose of this study was to determine whether eye drops containing 0.5% (w/v) sodium naproxen reduce a number of inflammatory responses produced by sodium arachidonate in the rabbit's eye. Sodium naproxen eye drops successfully reduced the primary signs of ocular inflammation elicited by 0.5% sodium arachidonate on conjunctiva and iris. However, the drug was less effective in reducing conjunctival inflammation induced by 1% sodium arachidonate. Sodium naproxen treatment significantly reduced the levels of prostaglandin E2 (PGE2), polymorphonuclear leukocytes and protein concentration in aqueous humor samples obtained from the eyes of rabbits treated with 0.5% sodium arachidonate whereas aqueous humor levels of leukotriene B4(LTB4) were not found significantly different from control rabbits. Interestingly, PGE2 as well as LTB 4 "de novo" production by corneas and lenses obtained from rabbits sacrificed 2 h after arachidonate and incubation "in vitro" for 20 min were significantly higher in samples taken from controls than in tissues obtained from the eyes treated with sodium naproxen eye drops. Finally, this drug treatment significantly antagonized the rise in intraocular pressure induced by 0.5% sodium arachidonate. Present data suggest that sodium naproxen may be employed topically to prevent ocular inflammatory reactions where the arachidonic acid cascade is activated.
A Flexible Rotor on Flexible Bearing Supports: Part I — Stability (1999)

Abstract An experimental study of the effects of bearing support flexibility on rotor stability is presented. A flexible roto supported by fluid film bearings on flexible supports was used with fifteen support configurations. The horizontal suppor stiffness was varied systematically while the vertical stiffness was kept constant. The support charactristics were determined experimentally by measuring the frequency response functions of the support structure at the bearing locations. These frequency response functions were used to calculate polynomial transfer functions that represented the support structure. Stability predictions were compared with measured stability thresholds. The predicted stability thresholds agree with the experimental data within a confidence bound for the logarithmic decrement of ±0.01. Predictions for the rotor on rigid supports are included for comparison.
Low power CMOS potentiostat for three electrodes amperometric chemical sensor (2011)

This paper presents two front-end electronics architectures, called potentiostats, developed for measuring gas concentrations with electro-chemical sensors. These potentiostats are designed to be integrated in wireless embedded systems. Consequently, the total power consumption is critical. An amperometric three-electrodes electro-chemical sensor has been chosen since it is powerless. Its electrical model has been determined in order to optimize the readout electronics associated. Two potentiostats have been realized in a 0.35μm CMOS process. The most power consumption optimized architecture designed in this work presents a consumption of 10.8μW over a range of detection included from 70nA to 25μA.
A neural stimulator front-end with arbitrary pulse shape, HV compliance and adaptive supply requiring 0.05mm<sup>2</sup> in 0.35&#x03BC;m HVCMOS (2011)

The required number of channels for neural stimulation is increasing; while in vitro arrays reached more than 10000 sites, implantable systems, e.g. for retinal or cortical stimulation, have not exceeded above 1600 which was achieved with a reduction to basic functionality and wireline control of rectangular stimulation pulses.
The <i>Arabidopsis ELF</i>3 gene regulates vegetative photomorphogenesis and the photoperiodic induction of flowering (1996)

Flowering in Arabidopsis thaliana is promoted by longday (LD) photoperiods such that plants grown in LD flower earlier, and after the production of fewer leaves, than plants grown in short-day (SD) photoperiods. The early-flowering 3 (elf3) mutant of Arabidopsis, which is insensitive to photoperiod with regard to floral initiation has been characterized elf3 mutants are also altered in several aspects of vegetative photomorphogenesis, including hypocotyl elongation. When inhibition of hypocotyl elongation was measured, elf3 mutant seedlings were less responsive than wild-type to all wavelengths of light, and most notably defective in blue and green light-mediated inhibition. When analyzed for the flowering-time phenotype, elf3 was epistatic to mutant alleles of the blue-light receptor encoding gene, HY4. However, when elf3 mutants were made deficient for functional phytochrome by the introduction of hy2 mutant alleles, the elf3 hy2 double mutants displayed the novel phenotype of flowering earlier than either single mutant while still exhibiting photoperiod insensitivity, indicating that a phytochrome-mediated pathway regulating floral initiation remains functional in elf3 single mutants. In addition, the inflorescences of one allelic combination of elf3 hy2 double mutants form a terminal flower similar to the structure produced by tfk1 single mutants. These results suggest that one of the signal transduction pathways controlling photoperiodism in Arabidopsis is regulated, at least in part, by photoreceptors other than phytochrome, and that the activity of the Arabidopsis inflorescence and floral meristem identity genes may be regulated by this same pathway.
Effect of Graded Replacement of Soybean Meal by Faba Beans (Vicia faba L.) or Field Peas (Pisum sativum L.) in Rations for Laying Hens on Egg Production and Quality (2007)

Two separate randomised block design experiments were each carried out for 13 months to investigate the effects of replacing, in-part, soybean meal (SBM) and wheat by graded levels of faba beans (FB) and field pea (FP) in a basal diet of wheat-SBM, balanced for amino acids, similar in crude protein (CP) and metabolisable energy (ME) on Lohmann hens. Traits studied included ; egg production, feed consumption, body weight gain, feed, energy and protein utilisations, and egg quality. Increasing dietary FB up 400g/kg (no SBM) decreased hen-day egg production, from 85 to 75%. Average egg mass significantly reduced from 50.8-43.5g/(hen*d). Feed consumption was similar (110 to 113g/(hen*d)). Increasing FB increased ME and CP required for egg production. FB had no significant effect on the shell strength, shell fraction and yolk index of eggs ; meanwhile it decreased the yolk fraction, and increased yolk colour, albumen fraction and albumen index. Most traits studied, were statistically similar up to 160g FB/kg feed. Increasing levels of FP up to 500g/kg did not significantly affect hen-day egg production and egg mass per day, although feed consumption increased. Body weight gain linearly dropped with increasing FP. FP had no significant effect on any of the egg quality traits studied. 16% FB and 50% FP could be included in layers diet without any significant effects on egg production or quality.
Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine (2018)

Better known as "ecstasy", 3,4-methylenedioxymethamphetamine (MDMA) is a small molecule that has played a prominent role in defining the ethos of today's teenagers and young adults, much like lysergic acid diethylamide (LSD) did in the 1960s. Though MDMA possesses structural similarities to compounds like amphetamine and mescaline, it produces subjective effects that are unlike any of the classical psychostimulants or hallucinogens and is one of the few compounds capable of reliably producing prosocial behavioral states. As a result, MDMA has captured the attention of recreational users, the media, artists, psychiatrists, and neuropharmacologists alike. Here, we detail the synthesis of MDMA as well as its pharmacology, metabolism, adverse effects, and potential use in medicine. Finally, we discuss its history and why it is perhaps the most important compound for the future of psychedelic science-having the potential to either facilitate new psychedelic research initiatives, or to usher in a second Dark Age for the field.
Neuropeptide Y is a vasoconstrictor in human nasal mucosa (1992)

Neuropeptide Y (NPY) is a neurotransmitter in sympathetic nerve fibers in human nasal mucosa. Like norepinephrine, NPY acts as a vasoconstrictor. An established method of nasal provocation was used to determine the effects of topically applied NPY on nasal resistance to airflow measured by anterior rhinomanometry, the protein content of nasal secretions, and the protein content of bradykinin-induced secretions. NPY (2.3 nmol) reduced the resistance to inspiratory airflow by 57 +/- 18% (P < 0.001) in 10 normal subjects and by 50 +/- 17% (P < 0.05) in 12 subjects with perennial rhinitis. In nasal provocations, NPY in doses of 0.1-10 nmol had no effect on vascular (albumin), glandular (lysozyme, glycoconjugate), or total proteins present in lavaged nasal secretions. Because the vasoconstrictor properties of NPY may only be apparent in the presence of increased vascular permeability and albumin exudation, bradykinin (BK) nasal provocation was performed. BK (500 nmol) significantly increase total protein (10- to 20-fold), albumin (10- to 30-fold), and glycoconjugate (2- to 5-fold) in lavage fluid. NPY (2.3 nmol) reduced BK-induced total protein by 59 +/- 15% (P < 0.05) and albumin by 63 +/- 17% (P < 0.02) but had no significant effect on glandular secretion. Therefore exogenous administration of NPY to the human nasal mucosa reduced nasal airflow resistance and albumin exudation without affecting submucosal gland secretion. NPY agonists may be useful for the treatment of mucosal diseases characterized by vasodilation, vascular permeability, and plasma exudation.
Information retrieval using robust natural language processing (1992)

We developed a fully automated Information Retrieval System which uses advanced natural language processing techniques to enhance the effectiveness of traditional key-word based document retrieval. In early experiments with the standard CACM-3204 collection of abstracts, the augmented system has displayed capabilities that made it clearly superior to the purely statistical base system.