gebhart/patrepeval huggingface dataset:
Anti-diabetic effect of Costus pictus leaves in normal and streptozotocin-induced diabetic rats (2008)

Costus pictus D. Don, commonly known as ‘insulin plant’ is a member of Zingiberacea family and is used as a munching dietary supplement for the treatment of diabetes in Southern India. The present study was carried out to evaluate the antidiabetic effect of Costus pictus leaves in normal and streptozotocin-induced diabetic rats. The oral feeding of aqueous leaf solution of this plant in diabetic rats for 28 days at a dosage of 2gm/kg body weight exhibited a significant (P&lt;0.001) reduction in fasting blood glucose level and a remarkable increase in serum insulin level. There was a significant reduction (P&lt;0.001) in serum parameters like SGOT, SGPT, lipids, triglycerides, total cholesterol, urea, TBARS, and albumin in diabetic rats treated with leaf solution. The body weight of diabetic rats was restored to normal state when treated with the C. pictus. Morphometric analysis of C. pictus-treated rat pancreatic islets showed a significant (P&lt;0.001) increase in the number and area of islets when compared with normal and diabetic control rats. Histopathology studies in liver and kidney of diabetic rats treated with aqueous solution did not show any marked difference from normal which revealed the non-toxic effect of this plant. Estimation of trace elements using particle induced X-ray emission analysis in the leaf was also determined to find the antidiabetic potential elements in this plant. Based on the above results it is evident that the leaves of C. pictus have antidiabetic effect and must be considered as a potential candidate for future studies on diabetes mellitus.
Sequence of release of fibrinopeptide A from fibrinogen molecules by thrombin or Atroxin. (1995)

During the conversion of fibrinogen to fibrin, two amino-terminal fibrinopeptides A (FPAs) are cleaved by thrombin from each molecule. During early phases of conversion, fibrin intermediates lacking one of two FPAs (des A fibrin) are produced, the level of which depends on whether the FPA cleavage sequence from each molecule is random of concerted. Random cleavage of FPA would produce higher levels of des A fibrin at any thrombin concentration than would concerted cleavage, and the level of this intermediate product would have an important effect on the ultimate structure of the fibrin clot. Because evidence bearing on this subject is conflicting, we carried out experiments to assess the FPA release sequence from fibrinogen by thrombin or by an FPA-cleaving snake venom enzyme, Atroxin. At timed intervals the enzymatic reaction was terminated by precipitation with trichloroacetic acid, and the precipitate was then treated with cyanogen bromide to produce a dimeric amino-terminal fragment. These disulfide-linked amino-terminal fragments of fibrinogen, containing both, one, or neither FPA, were then separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and their distribution quantified by densitometry. The rates of cleavage of the first FPA, k1, and of the second FPA, k2, were computed by fitting the data to equations for a consecutive chemical reaction. This analysis indicated that cleavage by either enzyme resulted in substantial amounts of des A fibrin intermediates. The ratio of the cleavage rates (k2/k1) was higher for thrombin (1.2 +/- 0.3) than it was for Atroxin (0.7 +/- 0.2) but indicates in both cases that the release rate of the second FPA is nearly the same as that of the first FPA.(ABSTRACT TRUNCATED AT 250 WORDS)
Airborne and ground information for lateral spacing during closely spaced parallel approach operations (2003)

At least 43 major airports in the US have parallel runways that are in very close proximity to each other - less than 4,400 feet apart. During visual meteorological conditions (VMC), when visual contact between aircraft is possible, airport capacity is greatly increased by having aircraft fly closely spaced parallel visual approaches. Under instrument meteorological conditions (IMC), airports with runways closer than 4,400 feet are required to revert to a single runway operation or to run dependent approaches. Each of these traffic flows greatly reduces the number of landing aircraft, sometimes by as much as 50%. This study examined the operational implementation of an airborne system which would support closely spaced parallel approach operations at airports with parallel runway center lines as close as 2,500 feet during IMC. Additionally, the study examined the system's requirements, both flight deck and ATC, that would support the implementation of closely spaced parallel approach operations at a major HUB airport. The primary objective of the AILS (airborne instrument landing system) concept is to enable safe independent approaches to parallel runways with runway spacing of at least 2,500 feet, through the development of concepts, procedures, and supporting technology.
The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity (2017)

Beclin-1 (BECN1) is an essential component of macroautophagy. This process is a highly conserved survival mechanism that recycles damaged cellular components or pathogens by encasing them in a bilayer vesicle that fuses with a lysosome to allow degradation of the vesicular contents. Mutations or altered expression profiles of BECN1 have been linked to various cancers and neurodegenerative diseases. Viruses, including HIV and herpes simplex virus 1 (HSV-1), are also known to specifically target BECN1 as a means of evading host defense mechanisms. Autophagy is regulated by the interaction between BECN1 and Bcl-2, a pro-survival protein in the apoptotic pathway that stabilizes the BECN1 homodimer. Disruption of the homodimer by phosphorylation or competitive binding promotes autophagy through an unknown mechanism. We report here the first recombinant synthesis (3-5 mg/L in an Escherichia coli culture) and characterization of full-length, human BECN1. Our analysis reveals that full-length BECN1 exists as a soluble homodimer (K<sub>D</sub> ∼ 0.45 μM) that interacts with Bcl-2 (K<sub>D</sub> = 4.3 ± 1.2 μM) and binds to lipid membranes. Dimerization is proposed to be mediated by a coiled-coil region of BECN1. A construct lacking the C-terminal BARA domain but including the coiled-coil region exhibits a homodimer K<sub>D</sub> 3.5-fold weaker than that of full-length BECN1, indicating that both the BARA domain and the coiled-coil region of BECN1 contribute to dimer formation. Using site-directed mutagenesis, we show that residues at the C-terminus of the coiled-coil region previously shown to interact with the BARA domain play a key role in dimerization and mutations weaken the interface by ∼5-fold.
Transport Abstraction Models for an SDN-Controlled Centralized RAN (2015)

In a centralized radio access network (C-RAN) scenario the joint coordination of radio (e.g., remote radio units, baseband units) and transport (e.g., optical cross connects) resources can be achieved via software defined networking (SDN) control plane, where a global orchestrator harmonizes the use of resources across all network segments. The more accurate the information about each domain (i.e., the abstraction of wireless and transport resources) is, the better will be the outcome of the orchestration work. This letter presents three transport resources abstraction models along with their corresponding orchestration policies. Their performance are compared showing that there is not a single best abstraction strategy that fits all the cases. If radio resources are scarce compared to transport resources, complex transport abstraction models are not needed. Contrariwise, if enough radio resources are widely available, more detailed abstraction models are required for achieving good network performance, but at the expense of an increased implementation complexity.
A literature review of the therapeutic mechanisms of art therapy for veterans with post-traumatic stress disorder (2016)

Post-traumatic stress disorder in combat veterans is often managed with the use of psychological intervention such as Cognitive Behavioural Therapy (CBT) and Eye Movement Desensitisation and Reprocessing (EMDR). There is a body of evidence that suggests that some individuals do not respond as well as others to such interventions. Other strategies in use to support veterans in recovery include art-based therapies and anecdotal evidence suggests that these have therapeutic impact for veteran groups that do not benefit from the aforementioned psychological therapies. This article describes a review of the literature associated with art therapy with combat veterans, aiming to ascertain what the therapeutic mechanisms are for veterans in using art therapy to manage post-traumatic stress disorder symptoms. Themes became evident within the literature review that are discussed and analysed, with resultant ideas for future research possibilities identified.
The IPUMS-International Project: Challenges and Methods of International Census Data Integration (2002)

Aquesta comunicació es va presentar a la Social Science History Association Conference, St. Louis (USA) Octubre 24-27 2002
Chemically induced phase separation in mixed vesicles containing phosphatidic acid. Optical study (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemically induced phase separation in mixed vesicles containing phosphatidic acid. Optical studyH. J. Galla and E. SackmannCite this: J. Am. Chem. Soc. 1975, 97, 14, 4114–4120Publication Date (Print):July 1, 1975Publication History Published online1 May 2002Published inissue 1 July 1975https://pubs.acs.org/doi/10.1021/ja00847a040https://doi.org/10.1021/ja00847a040research-articleACS PublicationsRequest reuse permissionsArticle Views228Altmetric-Citations111LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
THE C<sub>2</sub> OXIDATIVE PHOTOSYNTHETIC CARBON CYCLE (1997)

The C2 oxidative photosynthetic carbon cycle plus the C3 reductive photosynthetic carbon cycle coexist. Both are initiated by Rubisco, use about equal amounts of energy, must regenerate RuBP, and result in exchanges of CO2 and O2 to establish rates of net photosynthesis, CO2 and O2 compensation points, and the ratio of CO2 and O2 in the atmosphere. These concepts evolved from research on O2 inhibition, glycolate metabolism, leaf peroxisomes, photorespiration, 18O2/16O2 exchange, CO2 concentrating processes, and a requirement for the oxygenase activity of Rubisco. Nearly 80 years of research on these topics are unified under the one process of photosynthetic carbon metabolism and its self-regulation.
AC Losses in YBCO Coated Conductor With Inkjet Filaments (2007)

To achieve low ac losses in applied ac fields, YBa <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Cu <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> (YBCO) filaments were created on a RABiTS buffered substrate through solution inkjet deposition. A metal organic decomposition (MOD) solution was placed into an inkjet dispenser and filaments of widths of 100 mum and 0.8 mm were deposited on the substrate at a spacing of 50 to 100 mum. Each sample, which had a width of 1 cm and a nominal length of 4 cm, was placed in a perpendicular ac field and the ac losses were measured thermally as a function of the field strengths up to 100 mT and at frequencies between 60 Hz and 120 Hz. Samples with inkjet filaments had a high coupling loss. This coupling between filaments may extend along the entire sample length because removal of the conductor ends did not reduce the coupling loss contribution. Reduction in ac loss was observed in samples with laser-scribed filaments that were made from the same MOD solution.
ChemInform Abstract: Cycloaddition Reactions of Cephalosporin Compounds. Part 12. Cycloaddition Reactions of Vinylcephalosporins with Diazoalkanes. (1989)

Abstract The title reaction between the vinylcephalosporin (I) and excess diazomethane (IIIa) gives the pyrazolinylcephalosporin (IVa) as the main product, together with some amounts of the bisadduct (V) which increase with the reaction time.
A Stuty of the Changes of Mitochondria in Smooth Muscle Cells of Esophageal Wall and Their Clinic Significance (1995)

The ultrastructural Observation of mitochondria in the circular smooth muscle cells of the lower esophageal segment(LES)and esophageal body(EB)was studied under electonic microscope.The three-dimensional structure parameters of mitochondria were derived from two-dimensional electronic microscopic pictures by electronic microscopic picture steroanalysis.The more mature the fetus was,the more increasing the mitochodria in the LES were.in the volume density,area density,mean volume density as well as in mean section area density；but the more decreasing the long-short axes ratio was.No significant change in the number density of mitochodria was shown.The above density changes of mitochodria appeared more remarkable in LES than in EB.These suggest that the ultrastructure feature of mitochodria in the LES is the structural base of LES function which needs time to develop and mature.This is the fundamental explanation of gastroesophageal reflux(GER)which will alleviate and eliminate spontaneously as time goes on.

Key words: 
Esophagus; Mitochodria; muscle; Gastroesophageal reflux
The generation of order statistics in digital computer simulation: A survey (1978)

Order statistics are often needed in computer simulation. Common examples are quantile estimation and censored data test statistics. Methods for generating order statistics in various contexts are surveyed. Sorting and the use of histograms, the most general methods, are first discussed, followed by a method for non-identically distributed samples. Finally, the very powerful methods applicable to iid random variables are surveyed.
Mt. Etna Volcanic Aerosol and Ash Retrievals using MERIS and AATSR Data (2008)

Envisat MERIS and AATSR data have been acquired in the framework of the Eurorisk-Preview project. The project addresses European civil protections and proposes to develop, at the European scale, new information services to support the risk management. In Italy one of the most important natural risks is due to the presence of volcanoes. Mt. Etna in Sicily, displays persistent activity, periodically interrupted by eruptions, which emit volcanic aerosol and ash to different altitudes in troposphere affecting the central Mediterranean area. In order to test the use of MERIS and AATSR data to derive emitted particles parameters as optical depth, effective radius and the ash mass of particles, the already developed remote sensing techniques has been adapted. MERIS and AATSR data acquired during the Mt. Etna 2002-2003 volcanic eruption has been chosen. The use of VIS and TIR bands of the two sensor demonstrates the potential to derive useful information on plume particles and to monitor the volcanic plume during eruption if frequent and high resolution data is available in near real time.
ProbIN: Probabilistic inertial navigation (2010)

Numerous applications require accurate personal navigation for environments where neither GPS signals nor infrastructure beacons, such as WiFi, are available. Inertial navigation using low-cost sensors suffers from the noisy readings which leads to drifting errors over time. In this paper, we introduce a novel inertial navigation approach ProbIN using Bayesian probabilistic framework. ProbIN models the inertial navigation problem as a noise channel problem where we want to recover the actual motion/displacement of the user from the noisy sensor readings. Building on the top of dead reckoning, ProbIN learns a statistical model to map the noisy sensor readings to user's displacements instead of using the double integral of the acceleration. ProbIN also builds a statistical model to estimate the a priori probability of a user's trajectory pattern. Combining the mapping model and the trajectory model in a Bayesian framework, ProbIN searches for a trajectory that has the highest probability given the sensor input. Our experiments show that ProbIN significantly reduces the error of inertial navigation using low-cost MEMS sensors in mobile phones.
Short Term Electricity Load Forecasting on Varying Levels of Aggregation (2014)

We propose a simple empirical scaling law that describes load forecasting accuracy at different levels of aggregation. The model is justified based on a simple decomposition of individual consumption patterns. We show that for different forecasting methods and horizons, aggregating more customers improves the relative forecasting performance up to specific point. Beyond this point, no more improvement in relative performance can be obtained.
OPTIMALITY OF THE MAXIMUM LIKELIHOOD ESTIMATOR IN FIRST‐ORDER AUTOREGRESSIVE PROCESSES (1991)

Abstract. Let ρρ* be the maximum likelihood estimator (MLE) of the parameter ρ in the first‐order autoregressive process with normal errors. The problem of optimality in the sense of weighted squared error is considered rather than moments of asymptotic distributions. Many unbiased estimators can be constructed, but the two‐dimensional sufficient statistic is incomplete. It is shown that dEρ* ‐ ρ→ 0 uniformly in ρ, and that dE (ρ*)/ d ρ→ 1 for all |ρ| > 1. For |ρ| > 1, it is known that the asymptotic distribution of {I(ρ)} 12( ρ* ‐ ρ), where I (ρ) is the Fisher information, is Cauchy. It follows that the Cramèr‐Rao inequality will not yield useful results for investigating the limit of exact efficiency of any asymptotically unbiased estimator, including the MLE. For all |ρ| < 1, ρ* is asymptotically optimal in the sense of minimizing expected weighted squared error. In addition, for |ρ| < 1, ρ* minimizes the variance asymptotically.
Algebras of Derived Dimension Zero (2008)

We prove that a finite-dimensional algebra over an algebraically closed field is of derived dimension 0 if and only if it is an iterated tilted algebra of Dynkin type.
Testing of Stability and Spectroscopic Response of NiO(OH)/Ni<sub>2</sub>Si/n<sup>+</sup>/n-Si-Photoanode (1988)

A stable multilayer n-type silicon photoanode is produced by evaporating or sputtering a thin nickel film on the silicon surface and subsequently annealing in argon atmosphere. Its properties are investigated under various conditions. Under irradiation with intense light at a constant potential, no appreciable decrease of the photocurrent was observed during a period of 100 hours, while oxygen gas was evolved. The action spectra of this photoanode, measured under different potentials, showed that its absorption extends in a broad region.
Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, In vitro, ex vivo and in vivo studies (2011)

Three studies were performed to investigate the mechanism of action and evaluate the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol. The Ex vivo study on skin explants showed that caffeine and forskolin both stimulated glycerol release and demonstrates for the first time that retinol and carnitine in combination synergistically stimulated keratinocyte proliferation, which leads to an increase epidermal thickness. The double-blind, randomized, placebo-controlled clinical study associating circumference measurements on five selected parts of the body, cutaneous hydration measurements as well as blinded expert grading of skin aspect was conducted on 78 women who applied the product or placebo twice daily for 12 consecutive weeks. After 4 weeks of twice-daily application of the product, significant reductions in circumference of abdomen, hips-buttocks and waist were already observed. Improvements concerned all the measured body parts after 12 weeks. Orange peel and stubborn cellulite decreased significantly from 4 weeks of treatment and tonicity improved from 8 weeks, demonstrating that the product improved skin aspect. At the end of the study, eight parameters of the thirteen evaluated were significantly improved in the active group and compared with placebo.
Synthesis and Biological Behavior of a Boronated Analogue of the Antiestrogen U 23,469-M (1991)

A boronated analogue of the antiestrogen U 23,469-M (D. Lednicer, D. W. Emmert, S. C. Lyster, and G. W. Duncan, J. Med. Chem. 12, 881 (1969] was prepared, for possible use in neutron capture therapy of estrogen receptor-positive tumors. In this analogue, the terminal OH group was replaced by a B-decachloro-o-carboranyl residue. This compound showed a large, non-specific uptake in ZR 75-1 breast cancer-derived cells. It could partially inhibit the uptake of estradiol in these cells. Accumulation in the cells at physiologically obtainable concentrations was, however, too low to envisage a therapeutic effect following thermal neutron irradiation.
The Effect of Magnetic Field on Enhancing the Anisotropy of Melt-spun Nd-Fe-Co(-Zr)-B Alloy (1992)

Melt-spun and ribbons were prepared under an externally applied magnetic field. Magnetic properties in terms of anisotropy were evaluated by discussing the effect of textured structure of the ribbon samples as well as its powders. About 32 % increase in and 18.8 % increase in were observed along the perpendicular direction of the ribbon plane which is more prominent for the Nd-Fe-Co-Zr-B than for the Nd-Fe-Co-B alloy. The enhancement of magnetic anisotropy was monitored by measuring the anisotropy constant of each alloy as a function of quenching rate of the ribbon. It was found that for the melt-spun ribbon quenched at slow rate(less than 7 m/s) the magnetic field effect was overwhelmed by the heat gradient effect through the ribbon thickness while the field effect was prominent at intermediate quenching rate (more than 7~11 m/s). The reproducible maximum energy product, =16.4 MGOe can be obtained from the Nd-Fe-Co-Zr-B alloy.
RFID Privacy Using User-Controllable Uniqueness (2003)

In this paper, we propose two approaches to protect privacy in the ‘Digitally Named World’, which is the environment in which ‘radio frequency ID’s (RFIDs) are attached to any objects in the world, and any objects in the real world can be found by the readers of the RFID’s and the networked database system. One is the approach to conceal the permanent ID under a private ID that users give. The other approach is to assign partial ID sequence to a object, and the rest is given by user assignable RFID tags. These approaches both attempt to give users the controllability of the uniqueness of IDs from local to global, thereby enabling IDs private or public ones in the required state of the object’s life cycle.