gebhart/patrepeval huggingface dataset:
Effects of dose and adaptation time of ginger root (<i>Zingiber officinale</i>) on rumen fermentation (2011)

The present study evaluated the effects of different doses and different adaptation time of ginger powder on rumen fermentation in vivo. In Experiment 1, four sheep were used in a 4 x 4 Latin square design to evaluate the effects of three concentrations (5, 10, and 20 g/kg) of ginger powder on rumen fermentation. Total volatile fatty acid (VFA) concentration was decreased (P<0.05), but the fatty acid compositions, acetate-to-propionate ratio, pH, and ammonia-N concentration were unchanged by the addition of ginger powder. In Experiment 2, eight sheep were used to study the long-term adaptation of ginger powder on rumen fermentation. The addition of ginger powder decreased (P<0.05) the total VFA concentration from days 5 to 20, but these differences disappeared thereafter. Other rumen fermentation parameters were unchanged when ginger powder was added. Therefore, data from short-term in vitro fermentation studies may lead to erroneous conclusions and should be interpreted with caution.
Research on Optimization Algorithm of Urban Traffic Control and Its Application (2010)

Urban transport is a random and complex system.There are a lot of factors to affect urban traffic.According to the current traffic problems,the paper did several research and analysis on concrete examples and abstract features,which is from part and the overall city.Based on the existing hardware and algorithms,the paper proposed a new optimization strategy to facilitate intelligent traffic management.
Detection of Neoplastic Gastric Lesions Using Capsule Endoscopy: Pilot Study (2013)

Objectives. Capsule endoscopy is relatively noninvasive method and its use extends from the small bowel to the esophagus and colon. The aim of this study was to evaluate the feasibility and acceptability of capsule endoscopy for neoplastic gastric lesions. Methods. Capsule endoscopy (Pillcam ESO) was performed within 48 hours of esophagogastroduodenoscopy for eight patients who were diagnosed with gastric cancers, the size of which were less than 4 cm and who presented written consent. Patients changed position in a specified designed sequence every 30 seconds after capsule ingestion. Position change was repeated with ingestion of an effervescent agent. The rate of detection of intragastric lesions, observation of normal gastric anatomy and patient satisfaction between capsule endoscopy and esophagogastroduodenoscopy were compared. Results. Capsule endoscopy found four out of eight gastric lesions. The gastroesophageal junction was observed in seven of the eight cases, pyloric ring in five of the eight cases, and gastric angle in four of the eight cases. The patient satisfaction assessment questionnaire rated capsule endoscopy significantly higher than upper endoscopy in all categories. Conclusions. Capsule endoscopy was less effective than esophagogastroduodenoscopy and showed limited value in this feasibility study.
Issues in Transactions within Groups of Companies: A Greek and European Law Perspective (2005)

A traditional subject matter falling under the general heading of our Article is related to the Greek and European legislators' reaction towards the negative consequences and unfair practices in which intragroup transactions may result. Such transactions may result in detriment to shareholders, employees, and creditors, as well as of the state's interests regarding taxation policies. Currently, these considerations are not fully addressed by the traditional legal regime in Greece; as a result, discussion is still in progress. At an EU level, the recent legislative initiatives-in particular Directive 2002/87/EC on the supplementary supervision of credit institutions, insurance undertakings, and investment firms in a financial conglomerate-seek to introduce specific prudential legislation for financial conglomerates. These directives also take the first steps to align the legislation on the European level with national laws concerning financial groups and financial conglomerates in the same sector, thus ensuring a minimum level of equal treatment of these groups throughout the European Union. The main objective, however, of the new EU regime is to ensure that separate state regulators-who typically focus on one sector in order to ensure capital adequacy of the entities under their supervision-are not hindered because of the existence of cross-sector financial conglomerates. This requires specific measures which will prevent situations, for example, where capital is used at the same time as a buffer against risk in two or more entities belonging in the same financial conglomerate ("multiple gearing") and situations where a parent company issues debt and directs the proceeds as equity to its regulated subsidiaries ("excessive leverage"). [CONT]
CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity (2003)

Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal discharge activity have been postulated. We generated conditional mutant mice that lack expression of the cannabinoid receptor type 1 in principal forebrain neurons but not in adjacent inhibitory interneurons. In mutant mice,the excitotoxin kainic acid (KA) induced excessive seizures in vivo. The threshold to KA-induced neuronal excitation in vitro was severely reduced in hippocampal pyramidal neurons of mutants. KA administration rapidly raised hippocampal levels of anandamide and induced protective mechanisms in wild-type principal hippocampal neurons. These protective mechanisms could not be triggered in mutant mice. The endogenous cannabinoid system thus provides on-demand protection against acute excitotoxicity in central nervous system neurons.
Novel 5-Hydroxytryptamine (5-HT3) Receptor Antagonists. III. Pharmacological Evaluations and Molecular Modeling Studies of Optically Active 4,5,6,7-Tetrahydro-1H-benzimidazole Derivatives. (1996)

The R- and S-enantiomers of the 4,5,6,7-tetrahydro-1H-benzimidazole derivatives 3-8 were prepared by optical resolution. Each R-isomer, except for 3, was almost two orders of magnitude more potent than its S-isomer as a 5-hydroxytrptamine (5-HT3) receptor antagonist, as judged from they effect on the von Bezold-Jarisch reflex (B. J. reflex) in rats, the contraction of isolated guinea-pig colon and the receptor-binding affinity. The (--)-(R)-5-[(1-methyl-1H-indol-3-yl)carbonyl] derivative 6R.HCl (ramosetron = YM060) and (--)-(R)-5-[(1-indolinyl)carbonyl] derivative 4R.HCl (YM114 = KAE-393) given p.o. were hundreds of times more potent than 1 (ondansetron) and 2 (granisetron) in their inhibitory effects on cisplatin-induced emesis in ferrets and restraint stress-induced increases in fecal pellet output in rats. Three-dimensional molecular modeling studies suggested that the 'chiral selection' of the enantiomers might be influenced by the steric repulsion between the aromatic ring part and the conformationally restricted 4,5,6,7-tetrahydro-1H-benzimidazole ring in "equatorial-twist" conformation. In our pharmacophore model for the 5-HT3 receptor antagonist, a basic center exists at the left side of the aromatic-carbonyl plane when viewing from the aromatic part with the carbonyl oxygen atom upwards, whereas the "handedness" is ambiguous in the previously proposed model.
The MIXMAP‐model for international sport sponsorship (1997)

Abstract Posits that this analysis is based on the dependence of international sport sponsorship on the market audit and the individual product class/product form or brand environment. The MIXMAP‐model addresses the question of how the marketing mix framework can be used to analyse the competitive standing of a business organization, and how the outcomes of this analysis can be translated into practical tactics which capitalize on the organizations' strengths. The MIXMAP‐model was developed as a guide to make this transition from the strategic to the tactical level. The MIXMAP‐model begins by categorizing the product in the product‐life‐cycle concept and Boston Consulting Group matrix. This position is decisive for the intensity of the different elements (product, price, promotion, place) and their different variables. Discusses how a qualitative survey was used to provide an initial check of the theory and that the survey approach was a questionnaire to 60 multinationals in Germany, England, Italy and France.
A Learning-based Eye Detector Coupled with Eye Candidate Filtering and PCA Features (2007)

In this work, we present a system based on a Neural Network classifier for eye detection in human face images. This classifier works on eye candidate regions extracted from a face image and represented by a reduced number of features, selected by Principal Component Analysis. The regions are determined considering that in an image window containing the eye, the grey level distribution will generally assume a pattern of adjacent light-dark-light horizontal and vertical stripes, corresponding to the eyelid, pupil and eyelid, respectively. For training, validation and testing, a database was built with a total of 4,400 images. Experimental results have shown that the proposed approach correctly detects more eyes than any of two existing systems (Rowley-Baluja-Kanade and Machine Perception Toolbox), for eye location error tolerances from 0 to 5 pixels. Considering an error tolerance of 9 pixels, the correct detection rate achieved was above 90%.
Analytical and experimental investigation of aircraft metal structures reinforced with filamentary composites. Phase 1: Concept development and feasibility (1971)

The analytical and experimental investigations are described in the first phase of a program to establish the feasibility of reinforcing metal aircraft structures with advanced filamentary composites. The interactions resulting from combining the two types of materials into single assemblies as well as their ability to function structurally were studied. The combinations studied were boron-epoxy reinforced aluminum, boron-epoxy reinforced titanium, and boron-polyimide reinforced titanium. The concepts used unidirectional composites as reinforcement in the primary loading direction and metal for carrying the transverse loads as well as its portion of the primary load. The program established that several realistic concepts could be fabricated, that these concepts could perform to a level that would result in significant weight savings, and that there are means for predicting their capability within a reasonable degree of accuracy. This program also encountered problems related to the application of polyimide systems that resulted in their relatively poor and variable performance.
Photochemical Stereocontrol Using Tandem Photoredox–Chiral Lewis Acid Catalysis (2016)

The physical, biological, and materials properties of organic compounds are determined by their three-dimensional molecular shape. The development of methods to dictate the stereochemistry of organic reactions has consequently emerged as one of the central themes of contemporary synthetic chemistry. Over the past several decades, chiral catalysts have been developed to control the enantioselectivity of almost every class of synthetically useful transformation. Photochemical reactions, however, are a conspicuous exception. Relatively few examples of highly enantioselective catalytic photoreactions have been reported to date, despite almost a century of research in this field. The development of robust strategies for photochemical enantiocontrol has thus proven to be a long-standing and surprisingly difficult challenge. For the past decade, our laboratory has been studying the application of transition metal photocatalysts to a variety of problems in synthetic organic chemistry. These efforts have recently culminated in the discovery of an effective system in which the activity of a visible light absorbing transition metal photoredox catalyst is combined with a second stereocontrolling chiral Lewis acid catalyst. This dual catalyst strategy has been applied to a diverse range of photochemical reactions; these have included highly enantioselective photocatalytic [2 + 2] cycloadditions, [3 + 2] cycloadditions, and radical conjugate addition reactions. This Account describes the development of the tandem Lewis acid photoredox catalysis strategy utilized in our laboratory. It provides an analysis of the factors that we believe to be particularly important to the success of this seemingly robust approach to photocatalytic stereocontrol. (1) The photocatalysts utilized in our systems are activated by wavelengths of visible light where the organic substrates are transparent, which minimizes the possibility of competitive racemic background photoreactions. (2) The high degree of tolerance that Ru(bpy)<sub>3</sub><sup>2+</sup> and similar octahedral metal polypyridine complexes exhibit toward Lewis acids affords great flexibility in tuning the structure of the stereocontrolling chiral catalyst without perturbing the photoredox properties of the photocatalyst. (3) Synthetic chemists have amassed a substantial understanding of the features that are common in highly successful chiral Lewis acid catalyzed reactions, and these deep, well-validated insights are readily applied to the reactions of a variety of photogenerated intermediates. We hope that the recent success of this and similar dual catalytic systems will provide a useful foundation for the further development of powerful, stereocontrolled photochemical reactions.
High gain low power low noise trans-impedance amplifier for current sensing application (2017)

This paper work is about a transimpedance amplifier which have very high gain and sensitivity designed using cadence CMOS 0.18 μm technology with supply voltage of 1.8 V dissipates power 43μW suitable for current sensing signals from a sensor, molecular and nanodevice system. The integrator based circuit followed by an ADC. Because of the ability to handle large standing currents, the circuit is competent for use in the biological system where physical medium is also present. The trans-impedance amplifier (TIA) designed has low noise high gain which make it suitable to interface with ADC. A capacitive-feedback current amplifier drives current in to active load to obtain a 80 M-Om trans-impedance gain, 1.79 MHZ bandwidth phase response near 0.
A Cascaded Fuzzy Inference System for University Non-Teaching Staff Performance Appraisal (2011)

Most organizations use performance appraisal system to evaluate the effectiveness and efficiency of their employees. In evaluating staff performance, performance appraisal usually involves awarding numerical values or linguistic labels to employees performance. These values and labels are used to represent each staff achievement by reasoning incorporated in the arithmetical or statistical methods. However, the staff performance appraisal may involve judgments which are based on imprecise data especially when a person (the superior) tries to interpret another person's (his/her subordinate) performance. Thus, the scores awarded by the appraiser are only approximations. From fuzzy logic perspective, the performance of the appraisee involves the measurement of his/her ability, competence and skills, which are actually fuzzy concepts that can be captured in fuzzy terms. Accordingly, fuzzy approach can be used to handle these imprecision and uncertainty information. Therefore, the performance appraisal system can be examined using Fuzzy Logic Approach, which is carried out in the study. The study utilized a Cascaded fuzzy inference system to generate the performance qualities of some University non-teaching staff that are based on specific performance appraisal criteria.
Decreased TCGF activity in the culture medium of PHA stimulated peripheral mononuclear cells from patients with metastatic cancer. (1983)

Activities of T cell growth factor (TCGF) of conditioned media from PHA stimulated cultures of peripheral mononuclear cells (PHA-MNC-CM) were compared among patients with cancer, patients with non-malignant disease and normal persons. In nine out of 10 cases of cancer with metastasis (including extensive infiltration to surrounding tissues), the activities were much lower than normal persons, whereas in four out of five cases of cancer without metastasis, the activities were almost the same as those of normal persons. The low activities of PHA-MNC-CM from patients with metastatic cancer were not due to the older age of patients, nor did it seem to be attributed to the malnutritional state of patients. When we examined the activity using non-adherent MNC instead of the whole MNC, the activities in patients with metastatic cancer rose up to almost the normal levels. In normal persons the decline of the activities after 3 days of culture were not observed after the removal of adherent cells. Our data indicate that the adherent cells have a suppressive effect on TCGF production in both normal persons and cancer patients, but that the effect may be exaggerated in patients with metastatic cancer.
Central Effects of Catecholamines upon Mammary Contractility in Rats Are Neurally Mediated (1995)

We injected, i.e., intracerebroventricularly (ICV) or systematically, small amounts of adrenaline (ADR), noradrenaline (NA), isoproterenol (ISOP) and dopamine (DA) in urethane-anesthetized lactating rats, and determined the effects on isometrically recorded intramammary pressure (IMP) responses to exogenous oxytocin (OXY). While centrally administered ADR, NA and DA provoked increased IMP responses to OXY, the beta-adrenergic agonist ISOP induced the opposite effect. These effects were reversible, dose related and also occurred in hypophysectomized rats. However, when injected systematically, all adrenergic agonists but DA depressed IMP responses to OXY. Further experiments showed that central effects of catecholamines were exerted by regulating ductal tone, through the direct innervation of the mammary glands. Thus, whereas complete blockage of these effects occurred after selective denervation of the mammary glands, increased ductal tone resulted from ICV administration of ISOP. Finally, evidence was also obtained that antagonistic alpha- and beta-adrenergic mechanisms may interact with each other to regulate milk ejection, and with afferent signals from the mammary glands. Thus, beta-adrenergic inhibition upon IMP was counteracted by either NA administration or by activation of ductal mechanoreceptors. Together, these results suggest that regulation of milk ejection may involve neurally mediated influences on mammary contractility. Such actions would interact closely with afferents from the mammary gland influencing ductal tone.
Utilizing <i>Salmonella</i> for antigen delivery: the aims and benefits of bacterial delivered vaccination (2013)

Keywords:: antigen synthesisbiological containmentlysisrecombinant attenuated Salmonella vaccinesregulated delayed attenuationType II secretion systemType III secretion system
Improved Half Vector Space Light Transport (2015)

Abstract In this paper, we present improvements to half vector space light transport (HSLT) [ KHD14 ], which make this approach more practical, robust for difficult input geometry, and faster. Our first contribution is the computation of half vector space ray differentials in a different domain than the original work. This enables a more uniform stratification over the image plane during Markov chain exploration. Furthermore, we introduce a new multi chain perturbation in half vector space, which, if combined appropriately with half vector perturbation, makes the mutation strategy both more robust to geometric configurations with fine displacements and faster due to reduced number of ray casts. We provide and analyze the results of improved HSLT and discuss possible applications of our new half vector ray differentials.
Measurement of Energy Transfer Time in Colloidal Mn-Doped Semiconductor Nanocrystals (2010)

The exciton−dopant energy transfer time in colloidal Mn-doped CdS/ZnS core/shell nanocrystals was investigated via pump−probe transient absorption measurements. The energy transfer time was obtained from the comparative analysis of the dynamics of exciton relaxation in undoped and doped nanocrystal samples with well-defined doping radius and concentration. For this purpose, the transient absorption was measured in the near-IR region probing primarily intraband transition of excitons without signal saturation even at high exciton densities, which is particularly useful for studying the energy transfer in a wide range of exciton densities. With an increasing Mn doping concentration, exciton-dopant energy transfer became faster, effectively competing with both radiative and nonradiative relaxation of exciton. In the spherical Mn-doped CdS/ZnS core/shell nanocrystals studied here, the time scale of energy transfer between a single pair of exciton and Mn2+ ion was determined to be ∼60 ps.
Property-based rainwater drainage design and the impacts of climate change (2011)

Property-based rainwater drainage provision comprises a number of components broadly categorised as roof, surface or underground drainage. These systems are relied upon to prevent water ingress to the building and to avoid localised ponding or flooding. Recognition of the inherently unsteady response of the integrated network, in part driven by a particular rainfall event but also due to the transient nature of the fluid flows therein, is important in allowing an understanding of system performance under both current and future climate conditions. Codes and standards suggest that roof drainage systems, conventional or siphonic, are designed using a single rainfall intensity figure, representative of the most intense part of a longer storm, whereas runoff to surface and underground drainage is typically based on a single-peaked rainfall profile. Together with the difference in event duration typically adopted as part of the design process, this means that, unless a straightforward uplift factor is applied, then understanding the potential impacts of climate change on overall system performance can be difficult. Using numerical modelling techniques to analyse the performance of a case study site located in Edinburgh, this research identifies an appropriate common rainfall event from which a system-specific exceedance threshold is identified. Specification of this rainfall intensity facilitates an exploration of the impacts of climate change undertaken within the context of UKCP09 projections. Using gutter overtopping as an indicator of failure, this paper explores possible changes in the frequency of system under-capacity under varying future climate change scenarios. Practical application: Engineers are encouraged, in relevant codes and standards, to take account of the potential impacts of climate change when designing rainwater drainage systems for buildings. However, little guidance is offered therein on how to achieve this. This paper presents an example of UKCP09 climate change projections, specifically Weather Generator precipitation data, applied to a case study site that integrates roof, surface and underground drainage networks. Results illustrate the possible change in frequency of system failure, identified in this case as gutter overtopping.
A Classification of Experimental Models of Brain Ischemia (1976)

A system is presented for the classification of experimental models of cerebral ischemia by a mechanism of induction and distribution of the cerebral insult. Application of the proposed system to the scientific literature may help to resolve apparent conflicts in experimental findings and establish a frame of reference upon which to estimate the relevance of specific animal data to clinical phenomena. Experimental ischemic lesions and pathophysiological states must be considered the net product of variables in etiology and distribution of ischemia in the species chosen under the specific anesthesia selected.