gebhart/patrepeval huggingface dataset:
Dependence of workfunction on the geometries of single-walled carbon nanotubes (2004)

The effective workfunctions of single-walled carbon nanotubes of armchair (5,5) and zigzag (9,0) with various geometries have been calculated by first-principles calculations. The results show that the capped and H-terminated zigzag (9,0) carbon nanotubes exhibit a lower workfunction value than the armchair (5,5) nanotubes with a similar diameter. The open-ended (without H termination) (5,5) nanotube, on the other hand, shows a lower workfunction than the open-ended (9,0) structure. The former exhibits a significant formation of triple bonds at its mouth part after relaxation, which reduces the surface dipole and lowers its workfunction, the latter exhibits a higher density of unsaturated dangling bonds, raising its surface dipole and giving a higher value of workfunction.
Cholesterol efflux from and high‐density‐lipoproteins binding to cultured bovine vascular endothelial cells are higher than with vascular smooth muscle cells (1989)

Cholesterol metabolism was studied and compared in confluent cultures of adult bovine aortic endothelial and bovine aortic smooth muscle cells which were grown under similar conditions. The total cholesterol content/mg protein was only slightly higher in smooth muscle cells than in endothelial cells and upon exposure to [3H]cholesterol the maximal specific activity/mg protein obtained was similar in both cell types. Most (98%) of the incorporated [3H]cholesterol remained in the form of free cholesterol in both cell types, and provided a system for the study of cholesterol efflux. The role of high-density lipoproteins (HDL) and human serum in cholesterol influx and efflux, in both endothelial and smooth muscle cells, was studied. Net cholesterol transport in the cultures was calculated and net efflux was observed in both cell types. This was higher in endothelial than in smooth muscle cells and HDL was more efficient than human serum in promoting net cholesterol efflux. During the influx experiments, no conversion of [3H]cholesterol to [3H]cholesteryl ester was observed either in the cell layer or in the incubation medium. On the other hand, during efflux experiments when HDL but not human serum was the acceptor, some (about 6%) conversion of [3H]cholesterol to [3H]cholesteryl ester occurred in the incubation medium. 125I-HDL3 binding to endothelial and smooth muscle cells was studied and demonstrated saturation at a concentration of about 100 micrograms protein/ml for both cell types. However, endothelial cells bound about six times more 125I-HDL3 than smooth muscle cells. These studies indicate that vascular endothelial cells are more protected against cholesterol accumulation than vascular smooth muscle cells. The greater ability of endothelial cells to bind HDL complexes when compared with smooth muscle cells, and thereby to be more susceptible to HDL induced cholesterol efflux, may add a new mechanism through which endothelial cells protect the blood vessel from cholesterol accumulation.
Noninvasive Imaging of Angiogenesis With a <sup>99m</sup> Tc-Labeled Peptide Targeted at α <sub>v</sub> β <sub>3</sub> Integrin After Murine Hindlimb Ischemia (2005)

A 99mTc-labeled peptide (NC100692) targeted at alpha(v)beta3 integrin selectively localized to endothelial cells in regions of increased angiogenesis and could be used for noninvasive serial "hot spot" imaging of angiogenesis. This targeted radiotracer imaging approach is a major advance in tracking therapeutic myocardial angiogenesis and has an important clinical potential.
Efficacy and safety of anti‐amyloid‐<i>β</i> immunotherapy for Alzheimer's disease: a systematic review and network meta‐analysis (2017)

To review the optimality and safety of different anti-Amyloid-<i>β</i>(Aβ) immunotherapies for Alzheimer's disease (AD). Published randomized controlled trials were comprehensively reviewed from electronic databases (Cochrane library, Embase, Pubmed, and Google scholar). Pooled outcomes as mean difference or odds ratio values with 95% confidence interval were reported. The network estimates with confidence and predictive intervals for all pairwise relative effects was evaluated. Optimal intervention was ranked by benefit-risk ratio based on the surface under the cumulative ranking curve. Eleven eligible RCTs from 9 literatures, including 5141 patients and 5 interventions were included. The quality of evidence was rated low in comparisons. For efficacy, in terms of Mini-Mental State Examination, aducanumab and solanezumab are significantly effective than placebo. For safety, in terms of Amyloid-Related Imaging Abnormalities (ARIA), bapineuzumab and aducanumab are significantly worse than placebo. There were no significant differences in outcomes of Alzheimer's disease Assessment Scale-Cognitive subscale, Disability Assessment for Dementia, Adverse Events, and mortality. Given the clinical therapeutic effects of anti-A<i>β</i> immunotherapies for AD, aducanumab and solanezumab improve the cognitive function, while aducanumab and bapineuzumab may increase the risks of ARIA.
Artificial Intelligence and the Design of Expert Systems (1990)

Provides a thorough discussion of AI's theoretical foundations and advanced applications, including expert system design and knowledge-based programming. It is a wealth of advanced AI topics and applications that should appeal to a broad audience.
Surface ripples on silicon and gallium arsenide under picosecond laser illumination (1982)

We report experimental results on spontaneous periodic surface structures or ripples which occur on the surface of crystalline or ion-implanted semiconductors, using high-power picosecond laser pulses. We suggest that these surface ripples develop as the result of an exponentially growing interaction between the incident laser wave front and a scattered surface optical wave.
Ly49P recognition of cytomegalovirus-infected cells expressing H2-Dk and CMV-encoded m04 correlates with the NK cell antiviral response (2009)

Natural killer (NK) cells are crucial in resistance to certain viral infections, but the mechanisms used to recognize infected cells remain largely unknown. Here, we show that the activating Ly49P receptor recognizes cells infected with mouse cytomegalovirus (MCMV) by a process that requires the presence of H2-D(k) and the MCMV m04 protein. Using H2 chimeras between H2-D(b) and -D(k), we demonstrate that the H2-D(k) peptide-binding platform is required for Ly49P recognition. We identified m04 as a viral component necessary for recognition using a panel of MCMV-deletion mutant viruses and complementation of m04-deletion mutant (Deltam04) virus infection. MA/My mice, which express Ly49P and H2-D(k), are resistant to MCMV; however, infection with Deltam04 MCMV abrogates resistance. Depletion of NK cells in MA/My mice abrogates their resistance to wild-type MCMV infection, but does not significantly affect viral titers in mice infected with Deltam04 virus, implicating NK cells in host protection through m04-dependent recognition. These findings reveal a novel mechanism of major histocompatibility complex class I-restricted recognition of virally infected cells by an activating NK cell receptor.
Variation-Aware, Library Compatible Delay Modeling Strategy (2006)

Variability in digital integrated circuits makes timing verification an increasingly challenging task. Statistical static timing analysis has been proposed as a solution to this problem, but most of the work has concentrated in the development of timing engines for computing delay propagation. Such tools rely on the availability of delay formulas accounting for both cell and interconnect delay. In this paper, we concentrate on the impact of interconnect on delay and propose an extension to the standard modeling strategies that is variation-aware and compatible with such statistical engines. Our approach, based on a specific type of perturbation analysis, allows for the analytical computation of the quantities needed for statistical delay propagation. We also show how perturbation analysis can be performed when only the standard delay table lookup models are available for the standard cells. Results from applying our proposed modeling strategy to computing delays and slews in several instances accurately match similar results obtained using electrical level simulation
Research on model correction based on scattered point cloud data surface reconstruction (2011)

Surface reconstruction based on point cloud data has been extensively studied. In this paper, the original data has a lot of noise and without normal vector information, so we use Poisson surface reconstruction algorithm to create 3D heart model, which has good robustness for noisy and irregular point cloud data. Then correct the shape by removing or adding points from the model surface to perfect the heart model, and reconstruct the new model by Power Crust algorithm based on the correctional surface point cloud data with normal vector, which is quick, accurate and efficient and very suitable for fast model correction. The results not only accurately display the spatial relationship of the heart, but also can be discretionary scaling and rotation in 3D space. The visual 3D graphical structures of the reconstructed heart model can display diseases (cardiopathy & arrhythmia) and enable catheter navigation in real time, which can help doctors to detect and diagnose diseases effectively, and improve the accuracy and security of medical diagnosis.
Nine IM Accounts and Counting (2003)

Instant messaging has become nearly as ubiquitous as e-mail, in some cases far surpassing e-mail in popularity. But it has gone far beyond teenagers’ insular world to business, where it is becoming a useful communication tool. The problem, unlike e-mail, is that no common standard exists for IM, so users feel compelled to maintain multiple accounts, for example, AOL, Jabber, Yahoo, and MSN.
Keraring Intrastromal Segment Depth Measured by Spectral-Domain Optical Coherence Tomography in Eyes with Keratoconus (2017)

<i>Purpose</i>. To evaluate agreement between measured and intended distance of Keraring (Mediphacos, Belo Horizonte, Brazil) intracorneal ring segments from the anterior and posterior corneal surfaces. <i>Methods</i>. Twenty-six Keraring ICRS implanted in 24 keratoconic eyes were examined. The distance from the Keraring apex to the anterior corneal surface and the distance from the inner and the outer corners to the posterior corneal surface were measured 3 months postoperatively using spectral-domain optical coherence tomography. Agreement between measured distance and intended distance was assessed by calculating the absolute differences and 95% limits of agreement (95% LoA). <i>Results</i>. The mean absolute difference was significantly lower (<i>p</i> < 0.001) for the measurements taken at the inner corner (23.54 ± 15.90 <i>μ</i>m) than that for those taken at the apex (108.92 ± 62.72 <i>μ</i>m) and the outer corner (108.35 ± 56.99 <i>μ</i>m). The measurements taken at the inner corner were within ±25 and ±50 <i>μ</i>m of the intended distance in 15/26 (57.7%) and 24/26 (92.3%) cases, respectively, and showed the narrowest 95% LoA with the intended distance (-57.61 to 55.15 <i>μ</i>m). <i>Conclusions</i>. The distance of the inner corner from the posterior corneal surface showed the best agreement with the intended distance. This measurement is suitable for determining whether the actual Keraring depth matches the intended depth.
dWatch: A Personal Wrist Watch for Smart Environments (2012)

Intelligent environments, such as smart homes or domotic systems, have the potential to support people in many of their ordinary activities, by allowing complex control strategies for managing various capabilities of a house or a building: lights, doors, temperature, power and energy, music, etc. Such environments, typically, provide these control strategies by means of computers, touch screen panels, mobile phones, tablets, or In-House Displays. An unobtrusive and typically wearable device, like a bracelet or a wrist watch, that lets users perform various operations in their homes and to receive notifications from the environment, could strengthen the interaction with such systems, in particular for those people not accustomed to computer systems (e.g., elderly) or in contexts where users are not in front of a screen. Moreover, such wearable devices can reduce the technological gap introduced in the environment by home automation systems, thus permitting a higher level of acceptance in the daily activities and improving the interaction between the environment and its inhabitants. In this paper, we introduce the dWatch, a personal wearable notification and control device, integrated in an intelligent platform for domotic systems, designed to optimize the way people use the environment, and built as a wrist watch so that it is easily accessible, worn by people on a regular basis and unobtrusive.
Vectors for foreign peptides display on the surface of the major coat protein of filamentous bacteriophage (2000)

Two vectors were constructed for the purpose of displaying foreign peptides on the surface of the major coat protein of filamentous bacteriophage . These vectors offer the directional cloning of DNA encoding a foreign peptide at or near the N terminus of the major coat protein. The modified coat protein is interspersed with wild-type coat protein subunits of phage.
Monoclonal Antibodies to Somatostatin Receptor of Rat Brain (1992)

Murine Monoclonal antibodies (MAbs) to the rat brain somatostatin (SRIF) receptor were produced. Sp 2/0 myeloma cells were fused with splenocytes of Balb/c mice immunized with the soluble rat brain SRIF receptor which was partially purified by gel-filtration chromatography. Screening by radioligand ([125I-Tyr11]SRIF-14) binding inhibition assay yielded three stable cell lines producing IgG1, IgM, or IgA antibody. Autoradiographic study of the polyacrylamide gel electrophoresed under nondenaturing conditions revealed that these MAbs inhibited the ligand binding to the receptor, regardless of their incubation with the receptor prior to the ligand binding. The results suggest that the MAbs produced are the antibodies to the ligand binding site of the receptor, and bind to the receptor in competition with the ligand.
A Markov Decision Model for a Surveillance Application and Risk-Sensitive Markov Decision Processes (2010)

First, we model the dynamics of threat of an infrastructure as a continuous-time Markov decision process. Several structural results are derived. Furthermore, the model is approximately solved by using an index-based heuristics. Second, we consider discrete-time Markov decision processes. The criterion is to minimize the average value-at-risk for the discounted cost over a finite and over an infinite horizon. Moreover, the average value-at-risk criterion is considered for the average cost.
Molecular evidence for the origin of birds. (1994)

The major groups of amniote vertebrates appeared during a relatively short time span at the end of the Paleozoic Era, a fact that has caused difficulty in estimating their relationships. The fossil record suggests that crocodilians are the closest living relatives of birds. However, morphological characters and molecular sequence data from living amniotes have repeatedly challenged this hypothesis by indicating a bird-mammal relationship. DNA sequences from four slow-evolving genes (mitochondrial 12S and 16S rRNA, tRNAVal, and nuclear alpha-enolase) now provide strong statistical support for a bird-crocodilian relationship.
The wide-field imaging interferometry testbed: recent results (2006)

We present recent results from the Wide-Field Imaging Interferometry Testbed (WIIT). The data acquired with the WIIT is "double Fourier" data, including both spatial and spectral information within each data cube. We have been working with this data, and starting to develop algorithms, implementations, and techniques for reducing this data. Such algorithms and tools are of great import for a number of future missions, including the Space Infrared Interferometric Telescope (SPIRIT), the Submillimeter Probe of the Evolution of Cosmic Structure (SPECS), and the Terrestrial Planet Finder Interferometer (TPF-I)/Darwin. Recent results are discussed and future study directions are described.
Lipopolysaccharide induces synthesis of mouse colony-stimulating factor-1 in vivo (1997)

CSF-1 is a hemopoietic growth factor that regulates the survival, proliferation, and differentiation of mononuclear phagocytes, cells that are critical in the inflammatory response. In the case of Gram-negative infection, LPS plays an important role by inducing several cell types to produce the proinflammatory cytokines, IL-1, IL-6, and TNF-alpha. In this study, we examined the effects of i.p. administration of LPS on CSF-1 expression in the mouse. Two- to sevenfold increases in the CSF-1 concentrations determined by RIA were evident within hours of LPS administration in serum, liver, kidney, lung, spleen, brain, intestine, and heart. While alterations in the CSF-1 receptor-mediated clearance of CSF-1 appeared not to account for the increased growth factor concentrations in LPS-treated animals, there was an early LPS-induced reduction of splenic [125I]CSF-1 uptake consistent with tissue-specific down-modulation of CSF-1 receptors. The results of Northern analysis revealed increased expression of a CSF-1 mRNA species in liver, lung, kidney, spleen, intestine, and heart following LPS treatment, demonstrating that increased synthesis was responsible for the increased tissue CSF-1 concentrations. The increased expression and synthesis of CSF-1 in response to LPS may be essential for mobilizing and activating mononuclear phagocytes in the inflammatory response.
Fluorescent gold nanoclusters for in vivo target imaging of Alzheimer's disease (2016)

Fluorescent gold nanoclusters for<italic>in vivo</italic>target imaging provides a new way for rapid and early diagnosis of Alzheimer's disease.
Sensing stability and dynamic response of the F-Scan in-shoe sensing system: a technical note. (1998)

The objective of this study was to gain a better understanding of the F-Scan to determine its appropriate clinical application. Vertical pressure was applied to a sensor foil over the range of 10-80 kPa with or without the intervention of 0.2-0.8 mm thick felt. Sensor sensitivity reached a maximum without the felt, and decreased with increasing felt thickness, stabilizing at 48-74% of the maximum level when felt thickness exceeded 0.4 mm. This sensitivity change was caused by the slight difference in thickness of sensing areas from that of non-sensing areas. Dynamic response time was delayed by a mean of 0.32 s. Although the cause of this dynamic response delay remains unclear, it was considered to be inappropriate for accurate dynamic measurements. Therefore, rather than using F-Scan measurement to accurately obtain actual values, it should be used for relative comparisons of the plantar pressure distributions under constant conditions.
Chemistry and pharmacological properties of the pyridine-3-sulfonylurea derivative torasemide. (1988)

Out of a series of pyridine-3-sulfonylureas with diuretic activity torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea) has been proved to be one of the most active derivatives. In the rat, urinary volume and electrolyte excretions increased linearily with the logarithm of the dose, thus resembling the profile of a high ceiling diuretic. Experiments by oral and intravenous routes indicated that torasemide was equally potent both by oral and parenteral administration. Compared to furosemide, torasemide was 9-40 times more potent on weight basis in the rat. For the same natriuretic effect, however, potassium losses with torasemide were significantly less than with furosemide. The diuretic effect of torasemide lasted longer compared to that of furosemide. In accordance with the pharmacodynamic characteristics plasma elimination half-life of torasemide was about 1.5 h in the rat and bioavailability was nearly complete. Torasemide was 98-99% bound to plasma proteins. No in vitro interaction was found with the cumarine derivative warfarin.
Transverse-Mode Characteristics of InGaAs/GaAs Vertical-Cavity Surface-Emitting Lasers Considering Gain Offset (1993)

We have fabricated InGaAs/GaAs vertical-cavity surface-emitting lasers with modulation-doped graded distributed Bragg reflectors (DBRs) grown by metal-organic chemical vapor deposition (MOCVD). The threshold current was 3.2 mA. By observing the spontaneous emission through DBRs, we found that transverse mode behavior depends on gain characteristics. Single fundamental transverse-mode lasing is achieved at a negative gain offset and multiple transverse-mode lasing is achieved at a positive gain offset.
Surfactant Protein D, Soluble Intercellular Adhesion Molecule-1 and High-Sensitivity C-Reactive Protein as Biomarkers of Chronic Obstructive Pulmonary Disease (2013)

SP-D, sICAM and hs-CRP were significantly higher in COPD patients in comparison with controls. Moreover, SP-D, sICAM-1, and hs-CRP were significantly negatively correlated with FEV1%. Accordingly, estimation of these biochemical indices may be used as biomarkers for assessment of COPD severity.
Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses (2012)

This study shows the diverse immunogenicity of pDis/H5 co-administered with chicken IL-15 and IL-18,with pDis/H5 + pDis/IL-15 being a better vaccine candidate compared to other groups.
Anticoagulants Interfere with PCR Used To Diagnose Invasive Aspergillosis (2002)

Invasive aspergillosis is a disease that affects immunodepressed individuals and has become one of the leading causes of death in many transplant centers ([1][1]). Owing to the difficulties encountered in diagnosis of the disease and to the high sensitivity of the PCR technique, PCR-based methods
Communications in Burma (1942)

Research Article| January 26 1942 Communications in Burma Virginia Thompson Virginia Thompson Search for other works by this author on: This Site PubMed Google Scholar Far Eastern Survey (1942) 11 (2): 29–31. https://doi.org/10.2307/3022599 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Virginia Thompson; Communications in Burma. Far Eastern Survey 26 January 1942; 11 (2): 29–31. doi: https://doi.org/10.2307/3022599 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAsian Survey Search This content is only available via PDF. Article PDF first page preview Close Modal You do not currently have access to this content.