gebhart/patrepeval huggingface dataset:
Oxidation and reduction of Pd(100) and aerosol-deposited Pd nanoparticles (2011)

Using in situ high-pressure x-ray photoelectron spectroscopy, we have followed the oxidation and the reduction of Pd model catalysts in oxygen and CO pressures in the millibar range. The study includes a Pd(100) single crystal as well as SiO${}_{x}$-supported Pd nanoparticles of 15 or 35 nm diameter, respectively. We demonstrate that nanoparticles also form ultrathin surface oxides prior to the onset of the bulk PdO. The Pd nanoparticles are observed to bulk oxidize at sample temperatures 40 degrees lower than the single-crystal surface. In the Pd $3{d}_{5/2}$ and the O $1s$ spectrum, we identify a component corresponding to undercoordinated atoms at the surface of the PdO oxide. The experimentally observed PdO core-level shift is supported by density functional theory calculations. In a CO atmosphere, the Pd $3{d}_{5/2}$ component corresponding to undercoordinated PdO atoms is shifted by $+$ 0.55 eV with respect to PdO bulk, demonstrating that CO molecules preferably adsorb at these sites. CO coordinated to Pd atoms in the metallic and the oxidized phases can also be distinguished in the C $1s$ spectrum. The initial reduction by CO is similar for the single-crystal and the nanoparticle samples, but after the complete removal of the oxide we detect a significant deviation between the two systems, namely that the nanoparticles incorporate carbon to form a Pd carbide. Our results indicate that CO can dissociate on the nanoparticle samples, whereas no such behavior is observed for the Pd(100) single crystal. These results demonstrate the similarities, as well as the important differences, between the single crystals used as model systems for catalysis and nm-sized particles on oxide supports.
The Preparation and Characterization of Essentially Uniform Tobacco Mosaic Virus Particles (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation and Characterization of Essentially Uniform Tobacco Mosaic Virus ParticlesHelga Boedtker and Norman S. SimmonsCite this: J. Am. Chem. Soc. 1958, 80, 10, 2550–2556Publication Date (Print):May 1, 1958Publication History Published online1 May 2002Published inissue 1 May 1958https://pubs.acs.org/doi/10.1021/ja01543a049https://doi.org/10.1021/ja01543a049research-articleACS PublicationsRequest reuse permissionsArticle Views286Altmetric-Citations167LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Long-Term and Sustained COMP-Ang1 Induces Long-Lasting Vascular Enlargement and Enhanced Blood Flow (2005)

Vascular enlargement is a characteristic feature of angiopoietin-1 (Ang1)-induced changes in adult blood vessels. However, it is unknown whether tissues having Ang1-mediated vascular enlargement have more blood flow or whether the enlargement is reversible. We have recently created a soluble, stable and potent Ang1 variant, COMP-Ang1. In the present study, we investigated the effects of varied dose and duration of COMP-Ang1 on vascular enlargement and blood flow in the tracheal microvasculature of adult mice and explored a possible mechanism of long-lasting vascular enlargement. We found that COMP-Ang1 administered by adenoviral vector induced long-lasting vascular enlargement and increased tracheal blood flow. In contrast, short-term administration of COMP-Ang1 recombinant protein induced transient vascular enlargement that spontaneously reversed within a month. In both cases, the vascular enlargement resulted from endothelial proliferation. The COMP-Ang1-induced vascular remodeling is mediated mainly through Tie2 activation. Sustained overexpression of Tie2 could participate in the maintenance of vascular changes. Together, our findings indicate that sustained treatment with COMP-Ang1 can produce long-lasting vascular enlargement and increased blood flow.
On the Initial Trigger of Myasthenia Gravis and Suppression of the Disease by Antibodies Against the MHC Peptide Region Involved in the Presentation of a Pathogenic T-Cell Epitope (2001)

Myasthenia gravis (MG) is a disabling autoimmune disease caused by autoantibodies (auto-Abs) against the self-acetylcholine receptor (AChR). Although a great deal of information is known about the molecular and cellular parameters of the disease, its initial trigger, however, is not known. To study the possibility of the involvement of microbial antigens that mimic AChR in triggering MG, we have searched the microbial proteins in the data bank for regions that are similar in structure to the regions of human (h) AChR alpha chain recognized by auto-Abs in MG patients. Hundreds of candidate structures on a large number of bacterial and viral proteins were identified. To test the feasibility of the idea, we synthesized four microbial regions similar to each of the major autodeterminants of hAChR (alpha12-27, alpha111-126, alpha122-138, alpha182-198) and investigated their ability to bind auto-Abs in MG and normal sera controls. It was found that MG sera potentially recognized a significant number of these microbial regions. The results indicate that in some MG cases, immune responses to microbial antigens may cross-react with self-antigen (in this case hAChR) and could constitute initial triggers of the disease. Although anti-AChR Abs directly contribute to the degradation of AChR at the neuromuscular junctions, autoreactive T cells provide help to B cells that synthesize anti-AChR auto-Abs. To cause MG, T cells must recognize the pathogenic epitopes in the context of MHC class II molecules related to MG. The ability to regulate AChR presentation (hence AChR-reactive T-cell activation) could form the basis of an effective strategy for the control of autoimmunity in MG by selectively inhibiting the function of the Ir gene loci linked to disease susceptibility. An animal model of MG (experimental autoimmune MG, EAMG) can be induced in C57BL/6 (B6, H-2b) mice by immunization with Torpedo californica (t) AChR. A mutant mouse of B6, B6.C-H-2bm12 (bm12), which has three amino acid changes (at residues 67, 70, and 71) in the I-A beta(b) subunit, is resistant to EAMG development. Recently, we showed that region 62-76 of I-A beta(b), which contains the above residues, is involved in the binding to a pathogenic T-cell epitope within peptide t alpha146-162. We have prepared several monoclonal antibodies (mAbs) against peptide I-A beta(b)62-76, which are highly cross-reactive with I-A(b) molecules. These mAbs inhibited in vitro the proliferation of disease-related T cells of B6 specific to tAChR peptide t alpha146-162. Passive transfer of these mAbs suppressed the occurrence of clinical EAMG, which was accompanied by lower T-cell and Ab responses to tAChR. The results indicated that blocking disease-related MHC by targeting a disease-associated region on MHC molecules could be an effective, straightforward, and feasible strategy for immunointervention in MG.
The Condenser Motor (1929)

After a brief description of the construction and connections of the condenser motor the necessity of varying the capacitance is discussed, and the performance at start and under load is considered. Locus diagrams illustrating the operating performance in detail are given, followed by a more detailed discussion of starting torque. The Appendix gives the mathematical derivation of many of the formulas discussed.
A Mathematical Study of the Relaxed Optical Flow Problem in the Space $BV (\Omega)$ (1999)

This paper describes a variational approach for estimating a discontinuous optical flow from a sequence of images. Defined as the apparent motion of the image brightness pattern, the optical flow is very important in the computer vision community, where its accurate estimation is strongly needed. After a short overview of existing methods, we present a new variational method that we study in the space of bounded variations. We first present an integral representation of the optical flow problem which appears to be not lower semicontinuous. The relaxed functional is then calculated. We conclude by challenging questions about the possible numerical analysis of the abstract results.
Preparation and Characterisation of Sputtered Titanium- and Zirconium Nitride Optical Films (1993)

Multilayered interference coatings based on titanium- and zirconium nitride and designed for solar control have been prepared using reactive d c magnetron sputtering. Preparation effects and degradation mechanisms were investigated. It was shown that the quality of the nitride strongly depends on the degree of crystallinity in the underlying oxide. It has been shown that the nitride layer partly oxidizes as the top oxide layer is deposited. The degradation is enhanced with temperature. A thin sacrificial layer of aluminium deposited between successive depositions of nitride and oxide is shown to improve the optical performance of the coating as preparedm as well as after accelerated ageing tests. The optical properties of opaque and semitransparent films of zirconium nitride have been studied. A thorough investigation of the influence of composition, deposition rate, substrate temperature and film thickness on the optical response of the film was performed. Both photometric and ellipsometric methods were used to determine thicknesses and the optical constants at wavelengths ranging from 0.23 to 25 μm. The resulting values of n and k, in the wavelength intervals where these independent methods are applicable, have been shown to agree extremely well. The results so far indicate an even larger potential for zirconium nitride based solar control coatings as compared to the titanium nitride based. Access to optical constants derived from films of zirconium nitride of variable quality made multilayer modelling a powerful tool in the design and analysis of solar control coatings.
Synthesis and properties of organosoluble polyimides derived from 2,2′‐dibromo‐ and 2,2′,6,6′‐tetrabromo‐4,4′‐oxydianilines (2010)

Abstract Two new aromatic diamines, 2,2′‐dibromo‐4,4′‐oxydianiline (DB‐ODA 4 ) and 2,2′,6,6′‐tetrabromo‐4,4′‐oxydianiline (TB‐ODA 5 ), have been synthesized by oxidation, bromination, and reduction of 4,4′‐oxydianiline (4,4′‐ODA). Novel polyimides 6a–f and 7a–f were prepared by reacting DB‐ODA ( 4 ) and TB‐ODA ( 5 ) with several dianhydrides by one‐step method, respectively. The inherent viscosities of these polyimides ranged from 0.31 to 0.99 dL/g (0.5 g/dL, in NMP at 30°C). These polyimides showed enhanced solubilities compared to those derived from 4,4′‐oxydianiline and corresponding dianhydrides. Especially, polyimides 7a , derived from rigid PMDA and TB‐ODA ( 5 ) can also be soluble in THF, DMF, DMAc, DMSO, and NMP. These polyimides also exhibited good thermal stability. Their glass transition temperatures measured by thermal mechanical analysis (TMA) ranged from 251 to 328°C. When the same dianhydrides were used, polyimides 7 containing four bromide substituents had higher glass transition temperatures than polyimides 6 containing two bromide substituents. The effects of incorporating more polarizable bromides on the refractive indices of polyimides were also investigated. The average refractive indices ( n av ) measured at 633 nm were from 1.6088 to 1.7072, and the in‐plane/out‐of‐plane birefringences (Δ n ) were from 0.0098 to 0.0445. It was found that the refractive indices are slightly higher when polyimides contain more bromides. However, this effect is not very obvious. It might be due to loose chain packing resulted from bromide substituents at the 2,2′ and 2,2′,6,6′ positions of the oxydiphenylene moieties. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Least-Index Resolution of Degeneracy in Linear Complementarity Problems with Sufficient Matrices (1992)

This paper deals with the principal pivoting method (PPM) for the linear complementarity problem (LCP). It is shown here that when the matrix M of the LCP $(q,M)$ is (row and column) sufficient, the incorporation of a least-index pivot selection rule in the PPM makes it a finite algorithm even when the LCP is degenerate.
Coverage Optimization with a Dynamic Network of Drone Relays (2019)

The integration of aerial base stations carried by drones in cellular networks offers promising opportunities to enhance the connectivity enjoyed by ground users. In this paper, we propose an optimization framework for the 3-D placement and repositioning of a fleet of drones with a realistic inter-drone interference model and drone connectivity constraints. We show how to maximize network coverage by means of an extremal-optimization algorithm. The design of our algorithm is based on a mixed-integer non-convex program formulation for a coverage problem that is NP-Complete, as we prove in the paper. We not only optimize drone positions in a 3-D space in polynomial time, but also assign flight routes solving an assignment problem and using a strong geometrical tool, namely Bézier curves, which are extremely useful for non-uniform and realistic topologies. Specifically, we propose to fly drones following Bézier curves to seek the chance of approaching to clusters of ground users. This enhances coverage over time while users and drones move. We assess the performance of our proposal for synthetic scenarios as well as realistic maps extracted from the topology of a capital city. We demonstrate that our framework is near-optimal and using Bézier curves increases coverage up to 47 percent while drones move.
Recent Publications (2014)

   The following collection of Locke items, when taken together with ‘Recent Publications’ lists in previous issues, should provide fairly full coverage of work on Locke from 1981 to the present time. The Locke literature from 1900 to 1980 has been thoroughly covered in the book by Roland Hall and Roger Woolhouse, Eighty Years of Locke Scholarship: A Bibliographical Guide (Edinburgh University Press, 1983). The present list includes articles published in the previous issue of Locke Studies (Vol. 13). I am grateful to David Armitage and Roma Hutchinson for suggesting several items, and to those authors who sent offprints of their articles.
Brevican Is Degraded by Matrix Metalloproteinases and Aggrecanase-1 (ADAMTS4) at Different Sites (2000)

Brevican is a member of the lectican family of chondroitin sulfate proteoglycans that is predominantly expressed in the central nervous system. The susceptibility of brevican to digestion by matrix metalloproteinases (MMP-1, -2, -3, -7, -8, -9, -10, and -13 and membrane type 1 and 3 MMPs) and aggrecanase-1 (ADAMTS4) was examined. MMP-1, -2, -3, -7, -8, -10, and -13 degraded brevican into a few fragments with similar molecular masses, whereas the degradation products of aggrecanase-1 had apparently different sizes. NH(2)-terminal sequence analyses of the digestion fragments revealed that cleavages of the brevican core protein by these metalloproteinases occurred commonly within the central non-homologous domain. MMP-1, -2, -3, -7, -8, -10, and -13 preferentially attacked the Ala(360)-Phe(361) bond, whereas aggrecanase-1 cleaved the Glu(395)-Ser(396) bond, which are similar to the cleavage sites observed with cartilage proteoglycan (aggrecan) for the MMPs and aggrecanase-1, respectively. These data demonstrate that MMP-1, -2, -3, -7, -8, -10, and -13 and aggrecanase-1 digest brevican in a similar pattern to aggrecan and suggest that they may be responsible for the physiological turnover and pathological degradation of brevican.
Dementia in Hereditary Cerebral Hemorrhage With Amyloidosis-Dutch Type (1990)

Sixteen patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type were examined neuropsychologically. Abnormalities were found in all patients, and dementia was present in 12 of them. Three patients were tested twice at an interval of some years. All three exhibited a progressive intellectual deterioration and memory disturbance; in two of them there was no evidence of intercurrent strokes. Cerebral amyloid angiopathy can lead to dementia because it produces multiple focal cerebral lesions, but a chronic ischemic or metabolic effect on brain parenchyma may play a contributing role.
[Otoacoustic emissions and auditory brain stem responses in insulin dependent diabetic patients]. (2002)

Both of the groups (diabetic and control) had normal and undifferentiated results in tonal and impedance audiometry. The mean amplitudes of various DPOAEs were significantly reduced in the diabetic group compared with control subjects. No correlations were found between microangiopathy and DPOAE amplitudes reduced. ABR latencies were longer in diabetic patients when compared with those of control subjects. These findings indicate a central disturbance in the auditory pathway. Microvascular complications (retinopathy or nephropathy) were associated only with the prolongation wave I latency. In conclusion, the combined use of different procedures for monitoring the central and peripheral portions of the auditory pathway in diabetic patients showed the existence of the alterations in the cochlear micromechanics and in the retrocochlear auditory pathway.
Spectroscopic, crystallographic and computational studies of the formation and isomerization of cyclic acetals and ketals of pentonolactones (1994)

The different reactivities of D-ribonolactone, L-arabinonolactone, D-xylonolactone, D-lyxonolactone 2-deoxy-D-ribonolactone toward benzaldehyde and acetone in acidic media, were examined. The reactions involved complex equilibria and were investigated with extensive 13C NMR studies as well as X-ray crystallographic analysis of selected products. Molecular mechanics (MM2) and semiempirical (PM3 and AM1) calculations of some derivatives were carried out in order to facilitate structural and conformational assignments. The differences in reactivity observed for the reactions of D-pentono-1,4-lactones with benzaldehyde and acetone are rationalized in terms of their structural and conformational features.
An Information-Theoretic Approach to Individual Sequential Data Sanitization (2016)

Fine-grained, personal data has been largely, continuously generated nowadays, such as location check-ins, web histories, physical activities, etc. Those data sequences are typically shared with untrusted parties for data analysis and promotional services. However, the individually-generated sequential data contains behavior patterns and may disclose sensitive information if not properly sanitized. Furthermore, the utility of the released sequence can be adversely affected by sanitization techniques. In this paper, we study the problem of individual sequence data sanitization with minimum utility loss, given user-specified sensitive patterns. We propose a privacy notion based on information theory and sanitize sequence data via generalization. We show the optimization problem is hard and develop two efficient heuristic solutions. Extensive experimental evaluations are conducted on real-world datasets and the results demonstrate the efficiency and effectiveness of our solutions.
Nanoscale stacking fault–assisted room temperature plasticity in flash-sintered TiO <sub>2</sub> (2019)

Ceramic materials have been widely used for structural applications. However, most ceramics have rather limited plasticity at low temperatures and fracture well before the onset of plastic yielding. The brittle nature of ceramics arises from the lack of dislocation activity and the need for high stress to nucleate dislocations. Here, we have investigated the deformability of TiO<sub>2</sub> prepared by a flash-sintering technique. Our in situ studies show that the flash-sintered TiO<sub>2</sub> can be compressed to ~10% strain under room temperature without noticeable crack formation. The room temperature plasticity in flash-sintered TiO<sub>2</sub> is attributed to the formation of nanoscale stacking faults and nanotwins, which may be assisted by the high-density preexisting defects and oxygen vacancies introduced by the flash-sintering process. Distinct deformation behaviors have been observed in flash-sintered TiO<sub>2</sub> deformed at different testing temperatures, ranging from room temperature to 600°C. Potential mechanisms that may render ductile ceramic materials are discussed.
The Synthesis and Properties of Hydroxypyruvic Acid Phosphate (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis and Properties of Hydroxypyruvic Acid PhosphateClinton E. Ballou and Robert HesseCite this: J. Am. Chem. Soc. 1956, 78, 15, 3718–3720Publication Date (Print):August 1, 1956Publication History Published online1 May 2002Published inissue 1 August 1956https://pubs.acs.org/doi/10.1021/ja01596a045https://doi.org/10.1021/ja01596a045research-articleACS PublicationsRequest reuse permissionsArticle Views273Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts