gebhart/patrepeval huggingface dataset:
Additionsreaktionen und Ringspaltungen einiger heterocyclischer Verbindungen. Ein Beitrag zur Lehre von der Valenzlinienverteilung (1919)

aus der lietoenolform des Bthylidenbisacetessigesters ist die Eildung der cyclischen N-
Resilient trust management for Web service integration (2005)

In a distributed Web service integration environment, the selection of Web services should be based on their reputation and quality-of-service (QoS). Various trust models for web services have been proposed to evaluate the reputation of Web services/service providers. Current mechanisms are based on tracing the feedbacks to the past behaviors of Web services. However, very few of them consider the robustness and attack-resiliency of the trust models. In this paper, we present an attack resilient distributed trust management system in a Web service management environment. The proposed attack resilient trust model uses two vectors to capture the behavior and the trustworthiness of a Web service/service provider based on our analysis on the possible attacks against the trust models. We also present a set of experiments that show the effectiveness of our trust model in detecting malicious behavior of service providers.
Synthesis of polypyrimidoquinazolinetetraones from <i>N</i>,<i>N</i>′‐bis(mesyloxy)pyromellitimide and aromatic diamines (1975)

Abstract A novel class of polypyrimidoquinazolinetetraones was synthesized by the polymerization of N , N ′‐bis(mesyloxy)pyromellitimide with aromatic diamines in N ‐methyl‐2‐pyrrolidone in the presence of triethylamine as an acid acceptor. The polymerization proceeded probably through the formation of ring‐opened adducts, followed by elimination and rearrangement yielding polyamide‐isocyanates, which in turn were cyclized to give polypyrimidoquinazolinetetraones. These polymers, which were soluble in strong acids, had inherent viscosities in the range of 0.17–0.27. Thermogravimetric analyses indicated that they began to decompose at around 450°C in air.
Measured Behavior of Full-Scale Soil-Reinforced Segmental Retaining Wall (2003)

This paper presents the results of instrumentation of a two-level of soil-reinforced segmental retaining wall. Instrumentation items include the lateral wall displacements and the geogrid strains at several locations. The instrumentation is still long carried in order to examine long-term behavior. The result indicate that the upper wall has a significant effect on the behavior of the lower wall doubling the wall moved. The wall also exhibits significant post-construction movements that had ceased several months after the wall completed. The implication of the findings from this study was discussed in great detail.
Zinc Therapy of Acrodermatitis Enteropathica (1975)

The therapeutic effect of orally administered zinc was evaluated in an adult woman with acrodermatitis enteropathica. When she was off therapy and in clinical relapse the plasma zinc concentration (10 mug per 100 ml), serum alkaline phosphatase (3 1U per liter) and urine zinc excretion rate (39 mug per 24 hours) were extremely low. Di-iodohydroxyquin therapy was accompanied by a modest increase in plasma zinc concentrations. Oral zinc sulfate (220 mg three times a day or 50 mg twice a day) resulted in rapid and complete clinical remission, and in a return of plasma zinc, serum alkaline phosphatase and urinary zinc excretion to normal. These data are compatible with a severe zinc deficiency state and indicate that the inherited defect in this disease is either in or closely related to zinc metabolism. The beneficial effects of zinc therapy in this patient provide further confirmation of the efficacy of oral zinc in the treatment of acrodermatitis enteropathica.
Fast dictionary attacks on passwords using time-space tradeoff (2005)

Human-memorable passwords are a mainstay of computer security. To decrease vulnerability of passwords to brute-force dictionary attacks, many organizations enforce complicated password-creation rules and require that passwords include numerals and special characters. We demonstrate that as long as passwords remain human-memorable, they are vulnerable to "smart-dictionary" attacks even when the space of potential passwords is large.Our first insight is that the distribution of letters in easy-to-remember passwords is likely to be similar to the distribution of letters in the users' native language. Using standard Markov modeling techniques from natural language processing, this can be used to dramatically reduce the size of the password space to be searched. Our second contribution is an algorithm for efficient enumeration of the remaining password space. This allows application of time-space tradeoff techniques, limiting memory accesses to a relatively small table of "partial dictionary" sizes and enabling a very fast dictionary attack.We evaluated our method on a database of real-world user password hashes. Our algorithm successfully recovered 67.6% of the passwords using a 2 x 109 search space. This is a much higher percentage than Oechslin's "rainbow" attack, which is the fastest currently known technique for searching large keyspaces. These results call into question viability of human-memorable character-sequence passwords as an authentication mechanism.
Pervaporation of pharmaceutical waste streams and synthetic mixtures using water selective membranes (1999)

Abstract The separation characteristics of binary mixtures and complex pharmaceutical wastes were studied using commercial water selective pervaporation membranes. Various synthetic alcohol‐water (plus salt in some cases) systems and actual waste were utilized for this investigation. The total flux (at 60°C)for the ethanol‐water system decreased from 1.26 to 0.05 ty/m2/hrasthe feed ethanol concentration increased from 35 to 97 wt %. The separation factor (water/ethanol) was found to increase by about 100 times for the same range of concentration. The water/isopmpanol selectivity was found to be considerably higher than the water/ethanol selectivity. The total flux (at 60°C)for the isopropanol‐water system varied from 0.85 to 0.48 kg/m2/hras the feed isopropanol concentration was increased from 35 to 70 wt %. The effect of the presence of salt in the feed on the pervaporation separation was also studied. There was a noticeable effect only at high concentrations of salt in the alcohol‐water feed. Both the total flux and the membrane selectivity were observed to decrease at high salt concentrations. Pervaporation can be used for the volume reduction of pharmaceutical wastes. Pervaporation experiments were performed on a complex pharmaceutical “waste A” at two different temperatures. The total flux (0.9 kg/m2/hr) at 60°C for the waste was observed to be six times the total flux at 28°C whereas the TOC (total organic carbon) reduction factor (7.9) at 60°C was found to 2.5 times that at 28°C. A 87 % removal of the TOC and COD of the waste stream was observed. Pervaporation, using water selective membrane, was also performed on a dilute “Waste B” and only 40 % TOC/COD removal was obtained. Based on the experimental results and operating cost calculations, it can be concluded that pervaporation is indeed an attractive strategy for the volume reduction and for simultaneous reduction of organic concentration in the permeate stream.
Distinct and Redundant Functions of μ1 Medium Chains of the AP-1 Clathrin-Associated Protein Complex in the Nematode<i>Caenorhabditis elegans</i> (2000)

In the nematode Caenorhabditis elegans, there exist two micro1 medium chains of the AP-1 clathrin-associated protein complex. Mutations of unc-101, the gene that encodes one of the micro1 chains, cause pleiotropic effects (). In this report, we identified and analyzed the second mu1 chain gene, apm-1. Unlike the mammalian homologs, the two medium chains are expressed ubiquitously throughout development. RNA interference (RNAi) experiments with apm-1 showed that apm-1 and unc-101 were redundant in embryogenesis and in vulval development. Consistent with this, a hybrid protein containing APM-1, when overexpressed, rescued the phenotype of an unc-101 mutant. However, single disruptions of apm-1 or unc-101 have distinct phenotypes, indicating that the two medium chains may have distinct functions. RNAi of any one of the small or large chains of AP-1 complex (sigma1, beta1, or gamma) showed a phenotype identical to that caused by the simultaneous disruption of unc-101 and apm-1, but not that by single disruption of either gene. This suggests that the two medium chains may share large and small chains in the AP-1 complexes. Thus, apm-1 and unc-101 encode two highly related micro1 chains that share redundant and distinct functions within AP-1 clathrin-associated protein complexes of the same tissue.
Framework for Content Distribution Network Interconnection (CDNI) (2014)

This document presents a framework for Content Distribution Network Interconnection (CDNI). The purpose of the framework is to provide an overall picture of the problem space of CDNI and to describe the relationships among the various components necessary to interconnect CDNs. CDNI requires the specification of interfaces and mechanisms to address issues such as request routing, distribution metadata exchange, and logging information exchange across CDNs. The intent of this document is to outline what each interface needs to accomplish and to describe how these interfaces and mechanisms fit together, while leaving their detailed specification to other documents. This document, in combination with RFC 6707, obsoletes RFC 3466.
Grafting of Encapsulated Genetically Modified Cells Secreting GDNF into the Striatum of Parkinsonian Model Rats (2001)

In order to deliver glial cell line-derived neurotrophic factor (GDNF) into the brain, we have established a cell line that produces GDNF in a continuous fashion by genetic engineering. These cells were encapsulated and grafted into parkinsonian model rats that had received unilateral intrastriatal injection of 6-hydroxydopamine 2 weeks earlier. Neurochemical analysis showed that GDNF has been produced from the capsule for 6 months after grafting and histological analysis revealed good survival of GDNF-producing cells in the capsule 6 months after grafting. The density of nigrostriatal dopaminergic fibers in the striatum as well as the number of dopaminergic cell bodies in the substantia nigra recovered significantly after GDNF-producing cell grafting. These results suggest the possible application of GDNF-producing cell grafting for the treatment of Parkinson's disease.
Incompatibility of ketorolac tromethamine with selected postoperative drugs (1992)

Journal Article Incompatibility of ketorolac tromethamine with selected postoperative drugs Get access Andrea J. Knapp, Andrea J. Knapp pharmacy student, pharmacy intern College of Pharmacy, University of Toledo (UT), Toledo, OH, Department of Pharmacy, St. Luke's Hospital, Maumee, OH Search for other works by this author on: Oxford Academic Google Scholar Vincent F. Mauro, Pharm.D., Vincent F. Mauro, Pharm.D. Associate Professor of Clinical Pharmacy, Clinical Pharmacist College of Pharmacy, UT, Pharmacy Services, Medical College Hospitals, Toledo Search for other works by this author on: Oxford Academic Google Scholar Kenneth S. Alexander, Ph.D. Kenneth S. Alexander, Ph.D. Associate Professor of Pharmacy College of Pharmacy, UT Search for other works by this author on: Oxford Academic Google Scholar American Journal of Hospital Pharmacy, Volume 49, Issue 12, December 1992, Pages 2960–2962, https://doi.org/10.1093/ajhp/49.12.2960 Published: 01 December 1992
Modeling Dynamic Exchange of Gaseous Elemental Mercury at Polar Sunrise (2008)

At polar sunrise, gaseous elemental mercury (GEM) undergoes an exceptional dynamic exchange in the air and at the snow surface during which GEM can be rapidly removed from the atmosphere (the so-called atmospheric mercury depletion events (AMDEs)) as well as re-emitted from the snow within a few hours to days in the Polar Regions. Although high concentrations of total mercury in snow following AMDEs is well documented, there is very little data available on the redox transformation processes of mercury in the snow and the fluxes of mercury at the air/snow interface. Therefore, the net gain of mercury in the Polar Regions as a result of AMDEs is still an open question. We developed a new version of the global mercury model, GRAHM, which includes for the first time bidirectional surface exchange of GEM in Polar Regions in spring and summer by developing schemes for mercury halogen oxidation, deposition, and re-emission. Also for the first time, GOME satellite data-derived boundary layer concentrations of BrO have been used in a global mercury model for representation of halogen mercury chemistry. Comparison of model simulated and measured atmospheric concentrations of GEM at Alert, Canada, for 3 years (2002-2004) shows the model's capability in simulating the rapid cycling of mercury during and after AMDEs. Brooks et al. (1) measured mercury deposition, reemission, and net surface gain fluxes of mercury at Barrow, AK, during an intensive measurement campaign for a 2 week period in spring (March 25 to April 7, 2003). They reported 1.7, 1.0 +/- 0.2, and 0.7 +/- 0.2 microg m(-2) deposition, re-emission, and net surface gain, respectively. Using the optimal configuration of the model, we estimated 1.8 microg m(-2) deposition, 1.0 microg m(-2) re-emission, and 0.8 microg m(-2) net surface gain of mercury for the same time period at Barrow. The estimated net annual accumulation of mercury within the Arctic Circle north of 66.5 degrees is approximately 174 t with +/-7 t of interannual variability for 2002-2004 using the optimal configuration. We estimated the uncertainty of the model results to the Hg/Br reaction rate coefficient to be approximately 6%. Springtime is clearly demonstrated as the most active period of mercury exchanges and net surface gain (approximately 46% of annual accumulation) in the Arctic.
Lincomycin. VIII. 4'-Alkyl-1'-demethyl-4'-depropylclindamycins, potent antibacterial and antimalarial agents (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLincomycin. VIII. 4'-Alkyl-1'-demethyl-4'-depropylclindamycins, potent antibacterial and antimalarial agentsBarney J. Magerlein and Fred KaganCite this: J. Med. Chem. 1969, 12, 5, 780–784Publication Date (Print):September 1, 1969Publication History Published online1 May 2002Published inissue 1 September 1969https://pubs.acs.org/doi/10.1021/jm00305a013https://doi.org/10.1021/jm00305a013research-articleACS PublicationsRequest reuse permissionsArticle Views209Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Testing of ITER central solenoid coil insulation in an array (2002)

A glass-polyimide insulation system has been proposed by the US team for use in the central solenoid (CS) coil of the International Thermonuclear Experimental Reactor (ITER) machine and it is planned to use this system in the CS model coil inner module. The turn insulation will consist of 2 layers of combined prepreg and Kapton. Each layer is 50% overlapped with a butt wrap of prepreg and an overwrap of S glass. The coil layers will be separated by a glass-resin composite and impregnated in a VPI process. Small scale tests on the various components of the insulation are complete. It is planned to fabricate and test the insulation in a 4/spl times/4 insulated CS conductor array which will include the layer insulation and be vacuum impregnated. The conductor array will be subjected to 20 thermal cycles and 100000 mechanical load cycles in a liquid nitrogen environment. These loads are similar to those seen in the CS coil design. The insulation will be electrically tested at several stages during mechanical testing. This paper will describe the array configuration, fabrication process, instrumentation, testing configuration, and supporting analyses used in selecting the array and test configurations.
Partial Pillaring of Vermiculite by Aluminium Polycations (1994)

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Constellation rearrangement and spreading code rearrangement for hybrid ARQ in MC-CDMA (2003)

This paper presents two techniques that rearrange the data between retransmissions and can enhance the diversity gain from hybrid ARQ (hybrid automatic repeat request). One is constellation rearrangement that rearranges the signal constellation of QAM signals between retransmissions. The other is spreading code rearrangement that changes the spreading code with which the same symbol is transmitted in each retransmission. Simulation results show that those proposed schemes outperform type-H hybrid ARQ with packet combining, or chase combining.
Failure of reconstruction of the anterior cruciate ligament due to impingement by the intercondylar roof. (1993)

The relationship between impingement of the roof of the intercondylar notch on a reconstructed anterior cruciate ligament, and the subsequent stability and range of extension of the joint, was analyzed in forty-seven knees. The extent of the impingement was determined by analysis of the relationship of the tibial tunnel to the intersection of the line of slope of the intercondylar roof with the plane of the subchondral bone of the articular surface of the tibial plateau. These lines were drawn on a lateral roentgenogram that was made with the knee in maximum extension, two years after the operation. In all four knees in which the entire articular opening of the tibial tunnel was anterior to the slope of the intercondylar roof, there was severe impingement on the graft, and all four grafts failed. In the fourteen knees in which a portion of the articular opening of the tibial tunnel was anterior to the slope of the intercondylar roof, there was moderate impingement on the graft, and four grafts failed (an unacceptable rate of failure). There was no impingement in the knees in which the entire articular opening of the tibial tunnel was posterior to the slope of the intercondylar roof, and these knees were associated with the lowest rate of failure of the grafts (three of twenty-nine). Knees that had an impinged graft and regained a complete range of extension became unstable.
Control of c-fos and c-myc Proto-Oncogene Induction in Rat Thyroid Cells in Culture (1987)

Removal of TSH, insulin, and cortisol from the medium, and decreasing the serum content to 0.2%, abolishes both the proliferate and differentiated state of FRTL-5 rat thyroid cells in culture. In these basal conditions, the individual addition of TSH, insulin, insulin-like growth factor-I (IGF-I), phorbol 12-myristate 13-acetate (TPA), alpha 1-adrenergic agents, or A23187, increase c-myc and/or c-fos proto-oncogene expression. Under the same conditions, only the addition of TSH increased cAMP levels; 8-bromo-cAMP can increase c-myc or c-fos mRNA levels. Pretreatment of cells with phorbol 12,13-dibutyrate, an agent which down regulates the C-kinase, completely inhibits the effect of TPA on proto-oncogene expression but has no affect on the A23187 induced-increase. The sum of these results indicate that at least four separate signal systems independently increase c-myc or c-fos gene expression in FRTL-5 cells cAMP (TSH), C-kinase (TPA), Ca++/phosphoinositide (A23187), and that influenced by insulin/IGF-I. None of the ligands, when individually returned to cells in basal medium (no TSH, insulin, or cortisol and only 0.2% serum), increases cell number; norepinephrine, and A23187 do not increase [3H]thymidine incorporation into DNA under these conditions; and combinations of the ligands can be more than additive in effecting [3H]thymidine incorporation into DNA but are only additive in effecting proto-oncogene expression. Insulin/IGF-I plus TSH or insulin/IGF-I plus norepinephrine can increase both proto-oncogene expression and [3H]thymidine incorporation into DNA to the same extent; however, the former combination can increase cell number whereas the latter cannot. There is therefore no simple correlation between the ability of the above ligands to increase proto-oncogene expression and their ability to increase cell number or induce DNA synthesis. Under conditions where insulin and IGF-I increase proto-oncogene expression but not cell number, they can increase thyroglobulin gene expression. In the presence of TSH, insulin and IGF-I are not additive with each other in their ability to increase thyroglobulin or proto-oncogene gene expression but are additive in their ability to increase cell number. Proto-oncogene expression in FRTL-5 rat thyroid cells, as in other cell systems, may thus be related to functional as well as proliferative responses.
Networking requirements in a wireless system (2003)

Cordless systems together with cellular telephony will be the most important personal communication techniques in the future. Focusing on indoor applications, it will be necessary to implement closely spaced grid of micro-cells so as to use the limited radio spectrum more efficiently and to meet the expected capacity requirements. Among them, one could single out the growing demand for data services. Such reduced cell size makes the control tasks much more complex, demanding a broadband network and a distributed architecture. In order to design a network able to accommodate wireless services, the traffic generated must be modelled, particularly signalling traffic. Protocols for signalling must deal with roaming, call set-up and handover procedures. The authors present the results of computer simulations of an indoor wireless PABX system conforming to the digital European cordless telecommunications (DECT) standard.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Large-scale synthesis of single- and multiwalled carbon nanotubes by microwave CVD (2002)

Carbon nanotubes (CNTs) are an interesting class of nanostructures which can be thought of as arising from the folding layer of graphite (a graphene sheet) to form a hollow cylinder composed of carbon hexagons. However, practical applications are still limited by the intricate process of synthesis and the inability of present day methods for large scale production of carbon nanotubes. Moreover high quality nanotubes with functionalization capability with polymers are desired for polymer MEMS, Nanodevices and BioMEMS. In this paper, an innovative CVD approacah using microwave energy was developed for large scale production of single wall and multiwall carbon nanotubes (MWNTs). Straight and helical carbon nanotubes were obtained when acetylene decomposed over the cobalt catalyst at 700°C created by microwave field. The scanning electron microscopy (SEM) of microwave driven MWNTs revealed their homogeneous nature. The high resolution electron microscopy (HRTEM) showed typical MWNT has 26 layers. The average diameter of the tubes was observed 20-30 nm. Electronc microscope observations showed higher yield of nanotubes obtained from microwave CVD than thermal filament CVD method.