gebhart/patrepeval huggingface dataset:
The chemical ecology of <i>Biomphalaria glabrata</i> (say): The effects of media homotypically conditioned by adult snails on the growth of juveniles (1974)

Abstract Homotypically conditioned media (Hom. C.M.) produced by adult Biomphalaria glabrata weighing about 600 mg and fed on pure cellulose under bacteriostatic conditions at a density of one snail per 100 milliliter of standard snail water for three days significantly enhanced the growth of juveniles. Hom. C.M. produced under the same conditions by fasting snails that were previously fed on lettuce, also had a growth promoting effect but was less potent. The growth promoting factors have a molecular weight of 500‐10 4 , and appear to act directly on the snails and not indirectly by influencing the food medium. The extent to which absolute growth rate is stimulated by the growth factors correlates well with decrements in the conductivity and calcium concentration of the media. Possible modes of action of the growth factors are discussed. They appear not to influence the relative weights of shell, or body and water content of the snails. It is suggested that the adaptive significance of the growth factors is to facilitate rapid increase in numbers of this gregarious and often fugitive species when environmental conditions are favorable.
Chromosome and gene alterations in breast cancer as markers for diagnosis and prognosis as well as pathogenetic targets for therapy (2002)

Chromosomal abnormalities have been implicated in cancer development since the turn of the last century. Only during the past two decades, with advances in cytogenetics and molecular biology, has the genetic basis of neoplasia been firmly established, however, with chromosomal alterations being recognized as critical in the pathogenesis of human cancer. Recurrent chromosomal alterations provide cytological and molecular markers for the diagnosis and prognosis of disease. They also facilitate the identification of genes that are important in carcinogenesis and, ultimately, may lead to the development of targeted therapy. In breast cancer, the most prevalent malignancy among females, substantial progress has been achieved in identifying genes located at sites of recurrent chromosomal alterations and in profiling gene expression through the application of powerful cytogenetic and functional genomic techniques. Characterization of the molecular pathologic characteristics and gene-expression profiles of breast cancer should provide new clinical tools for the accurate diagnosis and prediction of prognosis as well as new targets for the development of therapeutic agents.
Improving Video Activity Recognition using Object Recognition and Text Mining (2012)

Recognizing activities in real-world videos is a challenging AI problem. We present a novel combination of standard activity classification, object recognition, and text mining to learn effective activity recognizers without ever explicitly labeling training videos. We cluster verbs used to describe videos to automatically discover classes of activities and produce a labeled training set. This labeled data is then used to train an activity classifier based on spatio-temporal features. Next, text mining is employed to learn the correlations between these verbs and related objects. This knowledge is then used together with the outputs of an off-the-shelf object recognizer and the trained activity classifier to produce an improved activity recognizer. Experiments on a corpus of YouTube videos demonstrate the effectiveness of the overall approach.
Impact of Donor-to-Recipient Weight Ratio on Survival After Heart Transplantation (2008)

Weight ratio did not predict mortality after heart transplantation. However, recipients with elevated pulmonary vascular resistance who received undersized hearts had poor survival. Furthermore, in the setting of high pulmonary vascular resistance, male recipients who received hearts from female donors had worse survival than those who received hearts from male donors. Extending donor criteria to include undersized hearts in select recipients should be considered.
Comparison of the reactivities toward oxidative addition of the dimethylplatinum(II) units in mononuclear and binuclear complexes with bis(diimine) ligands (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComparison of the reactivities toward oxidative addition of the dimethylplatinum(II) units in mononuclear and binuclear complexes with bis(diimine) ligandsJohn D. Scott and Richard J. PuddephattCite this: Organometallics 1986, 5, 12, 2522–2529Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/om00143a021https://doi.org/10.1021/om00143a021research-articleACS PublicationsRequest reuse permissionsArticle Views309Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study (2020)

The ongoing outbreak of Kawasaki-like multisystem inflammatory syndrome among children and adolescents in the Paris area might be related to SARS-CoV-2. In this study an unusually high proportion of the affected children and adolescents had gastrointestinal symptoms, Kawasaki disease shock syndrome, and were of African ancestry.
Facilitating intention prediction for humans by optimizing robot motions (2015)

Members of a team are able to coordinate their actions by anticipating the intentions of others. Achieving such implicit coordination between humans and robots requires humans to be able to quickly and robustly predict the robot's intentions, i.e. the robot should demonstrate a behavior that is legible. Whereas previous work has sought to explicitly optimize the legibility of behavior, we investigate legibility as a property that arises automatically from general requirements on the efficiency and robustness of joint human-robot task completion. We do so by optimizing fast and successful completion of joint human-robot tasks through policy improvement with stochastic optimization. Two experiments with human subjects show that robots are able to adapt their behavior so that humans become better at predicting the robot's intentions early on, which leads to faster and more robust overall task completion.
Photoinduced oxidation of carbon nanotubes (2003)

Photoinduced phenomena are of general interest for new materials. Recently, photoinduced molecular desorption of oxygen has been reported in carbon nanotubes. Here we present, using thermopower measurements, that carbon nanotubes when exposed simultaneously to UV light and oxygen exhibit photoinduced oxidation of the nanotubes. At least two plausible mechanisms for the experimentally observed photoinduced oxidation are proposed: (i) a lower energy barrier for the adsorption of photo-generated singlet oxygen, or (ii) due to the presence of defects in carbon nanotubes that may facilitate the formation of locally electron-deficient and electron-rich regions on the nanotubes which facilitate the adsorption of oxygen molecules on the nanotubes.
The Graphical Query Language: a tool for analysis of gene expression time-courses (2005)

The GQL package is freely available under the GNU general public license (GPL) at http://www.ghmm.org/gql
Twitter Mining for Sentiment Analysis in Tourism Industry (2019)

Tourism industry is probably most affected by the introduction of social media and micro-blogging websites. Millions of users share their perceptions, liking, choices and sentiments on social media. Therefore, Social media are the most preferred platforms for emotions and sentiment analysis. In this paper, we look at one such popular microblog called Twitter which is a great way to figure out how people feel about the popular travel websites using Twitter data. To do this, we Stream tweets from the Twitter API, Filter out the tweets that are relevant using search query, Perform sentiment analysis on Twitter data to figure out how they perceive each travel site and Store the tweets for additional analysis. This study is still in the initial stages in terms of tourism industry.
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy (2013)

Glial proliferation and activation are associated with disease progression in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia. In this study, we describe a unique platform to address the question of cell autonomy in transactive response DNA-binding protein (TDP-43) proteinopathies. We generated functional astroglia from human induced pluripotent stem cells carrying an ALS-causing TDP-43 mutation and show that mutant astrocytes exhibit increased levels of TDP-43, subcellular mislocalization of TDP-43, and decreased cell survival. We then performed coculture experiments to evaluate the effects of M337V astrocytes on the survival of wild-type and M337V TDP-43 motor neurons, showing that mutant TDP-43 astrocytes do not adversely affect survival of cocultured neurons. These observations reveal a significant and previously unrecognized glial cell-autonomous pathological phenotype associated with a pathogenic mutation in TDP-43 and show that TDP-43 proteinopathies do not display an astrocyte non-cell-autonomous component in cell culture, as previously described for SOD1 ALS. This study highlights the utility of induced pluripotent stem cell-based in vitro disease models to investigate mechanisms of disease in ALS and other TDP-43 proteinopathies.
GPU Accelerated Parallel Occupancy Voxel Based ICP for Position Tracking (2013)

Tracking the position of a robot in an un- known environment is an important problem in robotics. Iterative closest point algorithms us- ing range data are commonly used for position tracking, but can be computationally intensive. We describe a highly parallel occupancy grid iterative closest point position tracking algo- rithm designed for use on a GPU, that uses an Extended Kalman Filter to estimate motion between scans to increase the convergence rate. By exploiting the hardware structure of GPUs to rapidly nd corresponding points and by us- ing an occupancy map structure that can be safely modied in parallel with little synchro- nisation, our algorithm can run substantially faster than CPU based occupancy grid position tracking. We reduce the runtime from an aver- age of 33ms to just 3ms on a commodity GPU, allowing our algorithm to use more dense and more frequent data, resulting in improved accu- racy. Additionally, our solution can use a much larger occupancy grid without signicantly im- pacting runtime.
Blind de-mixing real-time algorithm of piecewise time series mixture (2003)

Lots of attention has been paid to the instantaneous blind source separation problem (BSS) configuration. However, a piecewise time series model of the BSS is an advance configuration of it. An aim of our control study was to determine if a high-order statistic can detect in real-time a piecewise time change occurrence in the mixing matrix in BSS problem. A preprocess and a postprocess were incorporated with a conventional ICA. The objective of preprocess is to detect the change and of the postprocess is to track over consistency of the permutation and phase shift. Those were achieved by using high-order statistic-kurtosis values. The method was applied to a Laplacian PDF (a synthesised speech) signal and Gaussian PDF note signal which mixed with a mixing matrix having a jump in its intensity and phase values. Results indicated that it could be used in real-time BSS problem when a sudden change is occurred in the recording transmission path and it is formulated in jumps in the entries of the mixing matrix. Still, the algorithm must be improved in order to deal with a slight change in the mixing matrix.
A new compact SAW low loss filter for mobile radio (1993)

The key objective of low loss filters for mobile radio applications is small size. For some years, SAW manufacturers have been working on SPUDT based filters which combine the advantages of low insertion loss, simple tuning, and single level processing, nevertheless the size is still too large for pocket telephone applications. We present a new SPUDT based low loss filter utilizing an improved architecture which gives a larger impulse response for a given size by means of folded acoustic paths. This technique was used to design a 71 MHz SAW filter on quartz. This filter fits in a SIP 5 package while the classical SPUDT filter requires for equivalent characteristics a DIP 14 package, corresponding to a 50% size reduction
Depression of vaccinal immunity to Marek's disease by infection with reticuloendotheliosis virus (1979)

The effect of infection with low-virulence, tissue culture-propagated strains of reticuloendotheliosis virus (REV) on protective vaccinal immunity against Marek's disease (MD) lymphomas was investigated. Vaccinated chickens inoculated at hatching with greater than 10(4) focus-forming units of REV and challenged with MD virus were poorly protected against MD lesion development as indicated by protective indices of 53 to 79% for strain CS (P less than 0.05) and 42 to 49% for strain T (P less than 0.01) compared to 78 to 100% for REV-free controls. Furthermore, the response of blood lymphocytes to mitogen stimulation and the antibody response to sheep erythrocytes and Brucella abortus were less in REV-inoculated chickens than in controls. The REV-induced depression of immune responses was more severe in chickens infected with mildly pathogenic strain T than in chickens infected with the apathogenic strain CS and was generally transient with both virus strains. Little or no depression of immune responses was observed in chickens inoculated with less than 10(3) focus-forming units of REV. These studies extend knowledge on the immunodepressive ability of low-virulence REV strains and establish that infection with these viruses depresses certain parameters of MD vaccinal immunity, an important model for cellular immunity against virus-induced neoplasia in the chicken.
Frequent Contribution of T Cell Clonotypes with Public TCR Features to the Chronic Response Against a Dominant EBV-Derived Epitope: Application to Direct Detection of Their Molecular Imprint on the Human Peripheral T Cell Repertoire (2000)

In an attempt to provide a global picture of the TCR repertoire diversity of a chronic T cell response against a common Ag, we performed an extensive TCR analysis of cells reactive against a dominant HLA-A2-restricted EBV epitope (hereafter referred to as GLC/A2), obtained after sorting PBL or synovial fluid lymphocytes from EBV-seropositive individuals using MHC/peptide multimers. Although TCR beta-chain diversity of GLC/A2+ T cells was extensive and varied greatly from one donor to another, we identified in most cell lines several recurrent Vbeta subsets (Vbeta2, Vbeta4, and Vbeta16 positive) with highly conserved TCRbeta complementarity-determining region 3 (CDR3) length and junctional motifs, which represented from 11 to 98% (mean, 50%) of GLC/A2-reactive cells. While TCR beta-chains expressed by these subsets showed limited CDR1, CDR2, and CDR3 homology among themselves, their TCR alpha-chains comprised the same TCRAV region, thus suggesting hierarchical contribution of TCR alpha-chain vs TCR beta-chain CDR to recognition of this particular MHC/peptide complex. The common occurrence of T cell clonotypes with public TCR features within GLC/A2-specific T cells allowed their direct detection within unsorted PBL using ad hoc clonotypic primers. These results, which suggest an unexpectedly high contribution of public clonotypes to the TCR repertoire against a dominant epitope, have several implications for the follow-up and modulation of T cell-mediated immunity.
보험상품의 핵심상품설명서 개선효과 추정-변액보험을 중심으로- (2014)

본 연구는 보험상품의 상품설명서가 소비자 친화적일수록 소비자의 이해도가 개선될 수 있음을 소비자 실험 결과에 대한 회귀분석과 성향점수 매칭분석을 통해 보이고 있다. 소비자 실험은 두 소비자 집단에 보험상품의 핵심설명서를 살펴보게 한 후 해당 상품의 소비자 이해도를 평가하는 방식으로 이루어졌다. 이를 위해 한 보험상품에 대하여 집단 A에는 현행 핵심설명서를, 집단 B에는 핵심설명서 개선안을 제시하는 방식으로 실험이 진행되었다. 여기서 핵심설명서 개선안은 저자들이 기존 핵심설명서의 표현방식을 굵은 글씨, 색상, 간결한 문장 등으로 바꾸고 질의응답 형식과 스토리텔링방식으로 내용 전개를 수정한 것이다. 두 소비자 집단의 핵심설명서 이해도 평가 결과에 대해서는 회귀분석과 더불어 분석 결과의 강건성을 확인하기 위하여 성향점수 매칭분석이 추가로 시행되었다. 분석 결과, 연구진이 제시한 핵심설명서 개선안이 현행 핵심설명서보다 소비자의 보험상품 이해도를 약 18~23%p 정도 높이는 것으로 나타났다. 본 연구는 핵심설명서 개선안을 직접 구성하고 소비자실험을 통해 개선안의 소비자 상품이해도 제고 효과를 확인했다는 점에서 기존 국내 연구들과 차이가 있다. 아울러 비록 소비자 이해도 평가 중 4개 항목에 한정된 분석이지만, 회귀분석과 함께 성향점수 매칭법을 통해 집단 간 정답률 차이를 정확하게 추정하려고 시도한 것은 본 연구의 의의라고 할 수 있다.
WIRELESS MEASUREMENT SYSTEM FOR NON-INVASIVE BIOMEDICAL MONITORING OF PSYCHO-PHYSIOLOGICAL PROCESSES (2009)

This paper presents new portable electronic measurement equipment for non-invasive biomedical monitoring of selected psychosomatic processes. The main goal is monitoring of the psycho-galvanic reflex (PGR) of the human skin that might be very useful for identification of psychical stress, performed in different medical as well as psychological experiments. A portable monitoring system, applicable also in wireless measurement environment, was designed and developed. Comparison to a standard laboratory-like bridge-based measurement system was done in terms of accuracy, sensitivity and other main features. The proposed measurement system employs measurement of the human skin conductivity using the interdigitated array (IDA) microelectrodes. The proposed monitoring equipment utilizes microprocessors with an RF wireless communication module used for data transfer between the measurement modules and a personal computer. A graphical user interface (GUI), developed in C++ under Windows XP platform, is used to provide necessary calibration of the measurement as well as storage, displaying and postprocessing of the measured data (real and imaginary components of the impedance as well as phase of the measured impedance). The measurement method itself and the achieved results are discussed. K e y w o r d s: biomedical monitoring, IDA microelectrodes, non-invasive monitoring, physiologic processes, psychogalvanic reflex, skin conductivity measurement
Principal strain changes precede ventricular wall thinning during transition to heart failure in a mouse model of dilated cardiomyopathy (2007)

This study was performed to elucidate the relation between in vivo measurements of two-dimensional principal strains and the progression of left ventricle (LV) wall thinning during development of dilated cardiomyopathy in the protein kinase C-epsilon (PKC-epsilon) transgenic (TG) overexpressing mouse heart. Principal two-dimensional strains, E1 and E2, were determined in the LV wall of the anesthetized mouse using cardiac MRI tagging at 14.1 T. PKC-epsilon TG provided a model of pure dilated cardiomyopathy without evidence of hypertrophy (PKC-epsilon TG, n = 6). Ejection fraction, wall thickness, and principal strains were determined at 1-mo intervals in hearts of PKC-epsilon TG vs. age-matched, nontransgenic mice (NTG, n = 5) from age 6 to 13 mo. Through the study, PKC-epsilon TG displayed lower ejection fraction than NTG. At 7 mo, average principal strain E1 in PKC-epsilon TG hearts was lower compared with NTG (PKC-epsilon TG = 0.14 +/- 0.03, NTG = 0.19 +/- 0.03, P < 0.05). The greatest reductions in regional E1 occurred in the lateral segments. The principal strain E2 did not change significantly in either group. At 9 mo, LV wall thinning occurred in PKC-epsilon TG mice (P < 0.01 vs. 8 mo) to 21% below values in NTG (P < 0.001). Average E1 strain diverged between PKC-epsilon TG and NTG hearts by 25-43%. These E1 changes preceded LV wall thinning and predated the eventual transition from a compensated circumstance to the dilated phenotype. The findings indicate a near step function in E1 depression that precedes the onset of LV wall thinning and suggest E1 as a prognostic indicator of dilated cardiomyopathy.
Targeted Overexpression of Parathyroid Hormone-Related Protein (PTHrP) to Vascular Smooth Muscle in Transgenic Mice Lowers Blood Pressure and Alters Vascular Contractility* (1999)

PTH-related protein (PTHrP) and its receptor are expressed in vascular smooth muscle cells and are believed to participate in the local regulation of vascular tone. To explore the function of locally produced PTHrP in vascular smooth muscle in vivo, we developed transgenic mice that overexpress PTHrP in smooth muscle using a smooth muscle alpha-actin promoter to direct expression of the transgene. In the PTHrP-overexpressing mice, messenger RNA expression was mainly restricted to smooth muscle-containing tissues. Several founders also expressed the transgene in bone and heart and exhibited striking abnormalities in the development of these tissues. In PTHrP-overexpressing mice, blood pressure was significantly lower than that in wild-type controls (121 +/- 3 vs. 135 +/- 2 mm Hg; P < 0.01). Moreover, the magnitude of the vasorelaxant response to iv infusions of PTHrP-(1-34)NH2 was significantly attenuated in the transgenic animals. A similar desensitization to PTHrP was observed in aortic ring and portal vein preparations. Surprisingly, PTHrP-overexpressing mice were also significantly less responsive to the hypotensive action of infused acetylcholine in vivo and to the relaxant actions of acetylcholine on aortic vessel preparations in vitro. In summary, we have successfully targeted overexpression of PTHrP to the smooth muscle of transgenic mice. When expressed in its normal autocrine/paracrine setting, PTHrP lowers systemic blood pressure and decreases vascular responsiveness to further relaxation by PTHrP and other endothelium-dependent vasorelaxants such as acetylcholine. We postulate that the heterologous desensitization to acetylcholine-induced relaxation in PTHrP-overexpressing blood vessels involves desensitization of second messenger/effector signaling pathways common to PTHrP and acetylcholine.
Novel Ergonomic Regenerative Braking System for an Electric Motorcycle (2018)

Despite several advances in regenerative braking (RB) strategies for electric vehicle applications, the developments associated to the case of an electric motorcycle remain very limited. Indeed, since the rear wheel load of an electric motorcycle is light during braking, the RB torque contribution is usually limited accordingly to avoid a rear wheel lockup. The fine-tune modulation of the RB torque by the driver is thereby constrained as well. As a contribution, this paper proposes an ergonomic novel strategy to pilot the RB torque. Hence, through the combined use of the twist grip, the "regen shift pedal" and the left-hand "regenerative brake lever," it emulates the engine braking effect of a gasoline motorcycle. Indeed, while braking, a predefined amount of RB torque, proportional to the vehicle speed, can be increased by "downshifting" the regen shift pedal and the resulting RB torque can be modulated through both the twist grip and the RB lever. More specifically, the purpose of the RB lever is to emulate the quick release effect of the clutch on the engine braking effect. Through simulations with identified parameters, the behavior of the strategy is verified while a more comprehensive verification will be done through road test in future work.