gebhart/patrepeval huggingface dataset:
Calculation of minimum number of registers in 2-D discrete wavelet transforms using lapped block processing (2002)

This paper considers architecture design of lapped block processing based discrete wavelet transforms. The emphasis is on computing the minimum number of registers required for various data format converters. Using life-time analysis, it is shown that the total number of on-chip line delays required for this architecture is approximately (N-1) where N is the order of the FIR filters used for the computation of the discrete wavelet transform.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver (1955)

Research Article| March 01 1955 Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver Françoise Appelmans; Françoise Appelmans 1Department of Physiological Chemistry, University of Louvain, Belgium Search for other works by this author on: This Site PubMed Google Scholar R. Wattiaux; R. Wattiaux 1Department of Physiological Chemistry, University of Louvain, Belgium Search for other works by this author on: This Site PubMed Google Scholar C. De Duve C. De Duve 1Department of Physiological Chemistry, University of Louvain, Belgium Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1955) 59 (3): 438–445. https://doi.org/10.1042/bj0590438 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation Françoise Appelmans, R. Wattiaux, C. De Duve; Tissue fractionation studies. 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver. Biochem J 1 March 1955; 59 (3): 438–445. doi: https://doi.org/10.1042/bj0590438 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1955 CAMBRIDGE UNIVERSITY PRESS1955 Article PDF first page preview Close Modal You do not currently have access to this content.
High efficiency polycrystalline silicon solar cells with conventional and selective emitters (2002)

Polycrystalline silicon solar cell emitter optimization was studied in two distinct situations. Using industrial Polix wafers with a diffused p/sup +/ layer at the back side, that were submitted to a special gettering process, a conventional p-doped emitter was back-etched, and a conversion efficiency of 15.6% was reached for 2*2 cm/sup 2/ cells. Another series of cells were made with a selective emitter, having enhanced doping under the front grid fingers and a selective emitter etchback between the fingers: in this case, cell efficiency was found to be improved as compared to the case of homogeneous emitters.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Effects of iron overload on the immune system. (2000)

Iron and its binding proteins have immunoregulatory properties, and shifting of immunoregulatory balances by iron excess or deficiency may produce severe, deleterious physiological effects. Effects of iron overload include decreased antibody-mediated and mitogen-stimulated phagocytosis by monocytes and macrophages, alterations in T-lymphocyte subsets, and modification of lymphocyte distribution in different compartments of the immune system. The importance of iron in regulating the expression of T-lymphocyte cell surface markers, influencing the expansion of different T-cell subsets, and affecting immune cell functions can be demonstrated in vitro and in vivo. The poor ability of lymphocytes to sequester excess iron in ferritin may help to explain the immune system abnormalities in iron-overloaded patients. Iron overload as seen in hereditary hemochromatosis patients enhances suppressor T-cell (CD8) numbers and activity, decreases the proliferative capacity, numbers, and activity of helper T cells (CD4) with increases in CD8/CD4 ratios, impairs the generation of cytotoxic T cells, and alters immunoglobulin secretion when compared to treated hereditary hemochromatosis patients or controls. A correlation has recently been found between low CD8+ lymphocyte numbers, liver damage associated with HCV positivity, and severity of iron overload in beta-thalassemia major patients. Iron overload, with its associated increases of serum iron levels and transferrin saturation, may cause a poor response to interferon therapy. Iron overload with hyperferremia is associated with suppressed functions of the complement system (classic or alternative types). High plasma ferritin content in patients with chronic, diffuse diseases of the liver (cirrhosis, chronic hepatitis), beta-thalassemia major, dyserythropoiesis, and hereditary hemochromatosis may induce the development of anti-ferritin antibodies with the production of circulating immune complexes. Increased body stores of iron in various clinical situations may tip the immunoregulatory balance unfavorably to allow increased growth rates of cancer cells and infectious organisms, and complicate the clinical management of preexisting acute and chronic diseases.
New N-amino acid derivatives of daunorubicin. (1986)

New N-amino acid derivatives of daunorubicin have been obtained by acylation of daunorubicin amino group with alpha, beta, and gamma amino acids and their N,N-dibenzyl derivatives. The results of the antitumor activity determination have evidenced that the change of the amino function position in the daunorubicin derivatives, in relation to that of the parent antibiotic, causes the loss of activity.
Real-Time Motion Tracking for Mobile Augmented/Virtual Reality Using Adaptive Visual-Inertial Fusion (2017)

In mobile augmented/virtual reality (AR/VR), real-time 6-Degree of Freedom (DoF) motion tracking is essential for the registration between virtual scenes and the real world. However, due to the limited computational capacity of mobile terminals today, the latency between consecutive arriving poses would damage the user experience in mobile AR/VR. Thus, a visual-inertial based real-time motion tracking for mobile AR/VR is proposed in this paper. By means of high frequency and passive outputs from the inertial sensor, the real-time performance of arriving poses for mobile AR/VR is achieved. In addition, to alleviate the jitter phenomenon during the visual-inertial fusion, an adaptive filter framework is established to cope with different motion situations automatically, enabling the real-time 6-DoF motion tracking by balancing the jitter and latency. Besides, the robustness of the traditional visual-only based motion tracking is enhanced, giving rise to a better mobile AR/VR performance when motion blur is encountered. Finally, experiments are carried out to demonstrate the proposed method, and the results show that this work is capable of providing a smooth and robust 6-DoF motion tracking for mobile AR/VR in real-time.
GIDL in Doped and Undoped FinFET Devices for Low-Leakage Applications (2012)

Investigation of gate-induced drain leakage (GIDL) in thick-oxide dual-gate doped- and undoped-channel FinFET devices through 3-D process and device simulations is presented. For a given gate length ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">L</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</sub> ) and gate dielectric thickness, the placement and grading of the drain junction and the channel doping are shown to have a tremendous impact on GIDL. Suppression of GIDL by as much as two orders of magnitude can be realized by formation of steep underlapped junctions for both doped- and undoped-channel devices. The prospect of low leakage levels in doped-channel high- <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">V</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> FinFETs makes them suitable for memory cell applications.
Regio- and Stereoselective Au(I)-Catalyzed Intermolecular Hydroalkoxylation of Aryl Allenes (2009)

In the presence of a catalytic amount of Ph3PAuNO3 and H2SO4, the hydroalkoxylation of allenes with alcohols has been shown to proceed smoothly and give allylic ethers in good yields and high regio- and stereoselectivity.
Evaluation of the IFCC-recommended procedure for serum aspartate aminotransferase as modified for use with the centrifugal analyzer. (1981)

Abstract The IFCC-recommended procedure for aspartate aminotransferase (EC 2.6.1.1) was adapted to the centrifugal analyzer and evaluated during five years. The main hindrance to widespread use of the recommended method is the need for pre-incubation with pyridoxal phosphate. The present method includes a 10-min pre-incubation with pyridoxal phosphate. Extensive evaluation of the method with and without this pre-incubation confirms earlier reports that it eliminates some significant errors, especially for samples from patients with cardiac disease. However, the pre-incubation can be briefer than the recommended 10 min and still provide acceptable results.
Photonic Materials Based on Mixtures of Cholesteric Liquid Crystals with Polymers (2003)

Cholesteric liquid crystals (CLC), polymer stabilized cholesteric liquid crystals (PSCLC), and polymer dispersed cholesteric liquid crystals (PDCLC) are promising dye-doped optically pumped lasing materials with an inherent photonic band gap structure. At low polymer concentrations, lasing from PSCLC occurs in modes near the edge of the selective reflection band. Electric field applied to the samples sandwiched between conducting glasses enhances PSCLC lasing emission. Lasing behavior changes dramatically at higher polymer concentrations in PDCLCs: numerous lasing peaks appear on the top of the emission band. New effects are explained in terms of lasing in photonic defect modes and photonic band gap modes.
A four-nucleotide insertion hotspot in the X chromosome located pyruvate dehydrogenase E1α gene (PDHA1) (1993)

Journal Article A four-nucleotide insertion hotspot in the X chromosome located pyruvate dehydrogenase E1α gene (PDHA1) Get access Fumie Takakubo, Fumie Takakubo The Murdoch Institute for Research into Birth Defects, Royal Children's HospitalFlemington Road, Parkville, Victoria 3052, Melbourne, Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar David R. Thorburn, David R. Thorburn The Murdoch Institute for Research into Birth Defects, Royal Children's HospitalFlemington Road, Parkville, Victoria 3052, Melbourne, Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar Hans-Henrik M. Dahl Hans-Henrik M. Dahl * The Murdoch Institute for Research into Birth Defects, Royal Children's HospitalFlemington Road, Parkville, Victoria 3052, Melbourne, Australia * To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 2, Issue 4, April 1993, Pages 473–474, https://doi.org/10.1093/hmg/2.4.473 Published: 01 April 1993 Article history Received: 04 January 1993 Revision received: 04 February 1993 Accepted: 04 February 1993 Published: 01 April 1993
Immunoluminometric Assay for the Midregion of Pro-Atrial Natriuretic Peptide in Human Plasma (2004)

The prohormone of atrial natriuretic peptide (proANP) is a polypeptide of 126 amino acids. Mature atrial natriuretic peptide (ANP) consists of amino acids 99–126 and comprises 98% of the natriuretic peptides in the circulation (1). The N-terminal portion of proANP, termed proANP1–98 or NT-proANP, has a much longer half-life than mature ANP and has therefore been suggested to be a more reliable analyte for measurement than mature ANP (2). In addition to other established indications, proANP has recently gained much interest as a potential new marker in the field of sepsis (3), emphasizing the need for a reliable assay for this molecule.

All sandwich immunoassays developed for proANP to date use an antibody against the N-terminal region of proANP1–98 combined with a second antibody against either the midregion (4) or C-terminal region (5)(6). However, under certain conditions, the N-terminal region might be minimally accessible for antibody binding (7)(8). Despite the described long half-life of proANP, results from various competitive immunoassays as well as HPLC analyses indicate that proANP1–98 can be subject to further fragmentation (9)(10).

We developed a new sandwich immunoassay for midregional proANP (amino acids 53–90; Fig. 1A⇓ ). With this assay, which was named B.R.A.H.M.S SERISTRA® (B.R.A.H.M.S AG), we measured proANP values in 325 healthy controls.

EDTA-plasma samples were collected at a blood bank (Red Cross) from 325 consecutive healthy blood donors (age range, 18–67 years; 52.9% male) without clinical evidence of acute disease or a history of chronic illness. Blood donors with risk factors for heart failure were not enrolled in the study. Written consent was obtained from …
An Engineered Bivalent Single-Chain Antibody Fragment That Increases Antigen Binding Activity (1997)

Bivalent single chain Fv (scFv) was constructed by fusing a polypeptide extension containing one or two cysteines to the COOH-terminus of an scFv antibody fragment. The scFv protein was expressed and secreted in a recombinant Pichia pastoris system as a dimer with a C-terminal disulfide bridge, as determined by Western blot analysis under non-reducing conditions. We found that the scFv construct with one cysteine in the C-extension (scFv-1Cys) exhibited a much higher dimer/monomer ratio than the two cysteine counterpart (scFv-2Cys). Binding activity measurements performed by means of a competitive radioimmunoassay showed that scFv-1Cys exhibited specific antigen binding activity, which was almost the same as that of the parental MAb, and approximately four- and fortyfold higher than those of the control scFv monomer and scFv-2Cys.
Gridding with continuous curvature splines in tension (1990)

Abstract A gridding method commonly called minimum curvature is widely used in the earth sciences. The method interpolates the data to be gridded with a surface having continuous second derivatives and minimal total squared curvature. The minimum-curvature surface has an analogy in elastic plate flexure and approximates the shape adopted by a thin plate flexed to pass through the data points. Minimum-curvature surfaces may have large oscillations and extraneous inflection points which make them unsuitable for gridding in many of the applications where they are commonly used. These extraneous inflection points can be eliminated by adding tension to the elastic-plate flexure equation. It is straightforward to generalize minimum-curvature gridding algorithms to include a tension parameter; the same system of equations must be solved in either case and only the relative weights of the coefficients change. Therefore, solutions under tension require no more computational effort than minimum-curvature solutions, and any algorithm which can solve the minimum-curvature equations can solve the more general system. We give common geologic examples where minimum-curvature gridding produces erroneous results but gridding with tension yields a good solution. We also outline how to improve the convergence of an iterative method of solution for the gridding equations.
Definition and Execution of Composite Web Services: The SELF-SERV Project. (2002)

Web services composition is emerging as a promising technology for the effective automation of businessto -business collaborations. It allows organizations to form alliances by connecting their applications, databases, and systems, in order to offer &quot;one-stops shops&quot; for their customers. The SELF-SERV project aims at providing tool support and middleware infrastructure for the definition and execution of composite Web services. A major outcome of the project has been a prototype system in which Web services are declaratively composed, and the resulting composite services can be orchestrated either in a peerto -peer or in a centralized way within a dynamic environment. Work is underway to extend this system in order to enable user-driven composition of Web services, and their execution in a mobile environment.
Ambulatory data aggregation and reduction for transmission over limited bandwidth network (2009)

There is a growing interest in linking the ambulance to hospital emergency room for transferring patients' vital signs' data to the hospital while the patients are in transit. If the ambulance is linked to the emergency room, physicians can monitor vital signs and issue instructions to the paramedics for stabilizing the patient. When a disaster strikes, scores of people have to be transferred to the hospital in ambulances. During an emergency situation, the number of patients in critical condition is overwhelming. We propose a scheme to transmit vital signs' data to the hospital in reduced and packed format via limited bandwidth wireless network. This scheme will help physicians in the hospital to monitor several patients who are in transit to the hospital. The effectiveness of data reduction techniques has been discussed for the purpose of transmission of data to the hospital on limited bandwidth wireless network.
Interaction of Inhibitors of the Vacuolar H<sup>+</sup>-ATPase with the Transmembrane V<sub>o</sub>-Sector (2004)

The macrolide antibiotic concanamycin A and a designed derivative of 5-(2-indolyl)-2,4-pentadienamide (INDOL0) are potent inhibitors of vacuolar H(+)-ATPases, with IC(50) values in the low and medium nanomolar range, respectively. Interaction of these V-ATPase inhibitors with spin-labeled subunit c in the transmembrane V(o)-sector of the ATPase was studied by using the transport-active 16-kDa proteolipid analogue of subunit c from the hepatopancreas of Nephrops norvegicus. Analogous experiments were also performed with vacuolar membranes from Saccharomyces cerevisiae. Membranous preparations of the Nephrops 16-kDa proteolipid were spin-labeled either on the unique cysteine C54, with a nitroxyl maleimide, or on the functionally essential glutamate E140, with a nitroxyl analogue of dicyclohexylcarbodiimide (DCCD). These residues were previously demonstrated to be accessible to lipid. Interaction of the inhibitors with these lipid-exposed residues was studied by using both conventional and saturation transfer EPR spectroscopy. Immobilization of the spin-labeled residues by the inhibitors was observed on both the nanosecond and microsecond time scales. The perturbation by INDOL0 was mostly greater than that by concanamycin A. Qualitatively similar but quantitatively greater effects were obtained with the same spin-label reagents and vacuolar membranes in which the Nephrops 16-kDa proteolipid was expressed in place of the native vma3p proteolipid of yeast. The spin-label immobilization corresponds to a direct interaction of the inhibitors with these intramembranous sites on the protein. A mutational analysis on transmembrane segment 4 known to give resistance to concanamycin A also gave partial resistance to INDOL0. The results are consistent with transmembrane segments 2 and 4 of the 16-kDa putative four-helix bundle, and particularly the functionally essential protonation locus, being involved in the inhibitor binding sites. Inhibition of proton transport may also involve immobilization of the overall rotation of the proteolipid subunit assembly.
Studies on Lipoxidase (1952)

The author examined the distribution of lipoxidase in 17 kinds of fatty seeds, but contrary to the presumption the correlation between the iodine value of these fats and the lipoxidase activity could not be demonstrated. The distribution of this enzyme in non-fatty peas and beans was examined. This enzyme was found also in the potato juice, but not in the extract of sweet potatoes. To research the action of lipoxidase on the rancidity of fats caused by the generation of microbes, the distribution of this enzyme in microbes was examined; this was found in Aspergillus and Rhizopus, but not in yeasts and bacteria.
NADP‐Dependent enzymes. II: Evolution of the mono‐ and dinucleotide binding domains (1997)

Nicotinamide adenine dinucleotides [NAD and NADP with both referred to as NAD(P)] are among the more diffuse redox cofactors. Despite their stereochemical similarity where the only difference is a phosphomonoester on the ribose near the adenine of NADP, they show different biochemical reactivities with NAD behaving as an oxidant and NADP as a reductant. NAD(P)-dependent enzymes generally share a common open α/β fold with few exceptions only recently structurally characterized. This study of the molecular evolution of the NAD(P) binding domains, possible given the large number of known molecular structures, addresses two main questions: 1) can a common fold exist in different biological systems (divergent evolution) and 2) does a relationship exist among similar biological systems that display different folds (convergent evolution)? Both the structures of mono- and dinucleotide binding domains have been classified by cluster analysis based on the similarity evaluated by their main chain Cα superposition. Moreover, the cofactor conformations and the stereochemical characteristics of their pockets have also been classified by analogous methods on the basis of the published tertiary structures. Two primary results appear: 1) the classification of the mononucleotide binding domains is different from that of the dinucleotide binding folds and 2) both divergent and convergent evolutionary pathways can be hypothesized, the latter less frequently observed and less pronounced but nevertheless evident. The generally accepted hypothesis that dinucleotide binding domains have evolved by gene duplication of primordial genes coding for the smaller mononucleotide binding domains is acceptable but the two halves of the resulting dinucleotide binding domains are evolutionarly uncorrelated. The NH2-terminal mononucleotide binding domain is less variable than the COOH-terminal half, probably because it involves the binding of the ADP moiety of NAD(P) invariant in all examined systems. There is evidence to postulate that evolutionary pathways for NAD(P)-dependent enzymes are both divergent and convergent. In fact, nearly all combinations of similarity/dissimilarity in overall fold, cofactor conformation, and cofactor binding pocket structural characteristics for each enzyme pair examined are possible. The NAD(P)-dependent enzymes apparently provide a canonical example of an evolutionary principle that “anything goes.” © 1997 Wiley-Liss Inc.