gebhart/patrepeval huggingface dataset:
Artificial Spinning and Characterization of Silk Fiber from <i>Bombyx </i><i>m</i><i>ori</i> Silk Fibroin in Hexafluoroacetone Hydrate (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTArtificial Spinning and Characterization of Silk Fiber from Bombyx mori Silk Fibroin in Hexafluoroacetone HydrateJuming Yao, Hiromi Masuda, Chenhua Zhao, and Tetsuo AsakuraView Author Information Department of Biotechnology, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan Cite this: Macromolecules 2002, 35, 1, 6–9Publication Date (Web):December 4, 2001Publication History Received27 July 2001Published online4 December 2001Published inissue 1 January 2002https://pubs.acs.org/doi/10.1021/ma011335jhttps://doi.org/10.1021/ma011335jrapid-communicationACS PublicationsCopyright © 2002 American Chemical SocietyRequest reuse permissionsArticle Views1764Altmetric-Citations150LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biomimetic materials,Biopolymers,Fibers,Peptides and proteins,Solvents Get e-Alerts
An approach to motion planning for mobile manipulation (2002)

Increasing the flexibility of robot systems has been one of the main objectives of robotics research in recent years, There are various approaches to achieve this: increasing fault-tolerance on different levels, the development of sophisticated sensors, grippers and manipulators, and the use of learning techniques. But the field of operation of such smart systems is still limited to a rather small area. Mobile manipulation is another facet of increasing the flexibility of a robot system. By exploiting the mobility of a platform, the dexterous workspace of manipulators can be considerably increased. One main research topic on mobile manipulation is the decomposition of the motion of the tool-center-point into manipulator motion and platform motion. In this paper a new online approach to this decomposition is presented which allows the consideration of complex obstacles and multiple manipulators mounted on the platform. Simulation studies verify the suitability of the approach. Some of the realized algorithms have been applied to a real mobile two-arm system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
In vivo small animal micro-CT using nanoparticle contrast agents (2015)

Computed tomography (CT) is one of the most valuable modalities for in vivo imaging because it is fast, high-resolution, cost-effective, and non-invasive. Moreover, CT is heavily used not only in the clinic (for both diagnostics and treatment planning) but also in preclinical research as micro-CT. Although CT is inherently effective for lung and bone imaging, soft tissue imaging requires the use of contrast agents. For small animal micro-CT, nanoparticle contrast agents are used in order to avoid rapid renal clearance. A variety of nanoparticles have been used for micro-CT imaging, but the majority of research has focused on the use of iodine-containing nanoparticles and gold nanoparticles. Both nanoparticle types can act as highly effective blood pool contrast agents or can be targeted using a wide variety of targeting mechanisms. CT imaging can be further enhanced by adding spectral capabilities to separate multiple co-injected nanoparticles in vivo. Spectral CT, using both energy-integrating and energy-resolving detectors, has been used with multiple contrast agents to enable functional and molecular imaging. This review focuses on new developments for in vivo small animal micro-CT using novel nanoparticle probes applied in preclinical research.
Layered Graphene/Quantum Dots for Photovoltaic Devices (2010)

Ganz einfach lassen sich Filme aus Graphen- und Quantenpunkt(QD)-Schichten aus wässrigen Lösungen auf transparenten leitfähigen Indiumzinnoxid(ITO)-Substraten aufbringen. Graphen eignet sich dank seiner Struktur und günstigen Austrittsarbeit gut für die Sammlung und Übertragung durch Licht erzeugter Ladungen auf die Elektrode; als Resultat erhält man ein hocheffizientes Photovoltaikelement (siehe Bild; IPCE=Photostromeffizienz, SWNT=einwandige Kohlenstoffnanoröhre).
Attention-Deficit Hyperactivity Disorder Symptoms in a Clinic Sample of Children and Adolescents with Pervasive Developmental Disorders (2006)

ADHD symptoms are pervasive in clinically referred children and adolescents with ASD.
Admission macrophage migration inhibitory factor predicts long-term prognosis in patients with ST-elevation myocardial infarction (2018)

STEMI patients with high admission MIF level experienced a poorer recovery of cardiac function and worse long-term adverse outcomes. Combination of Nt-proBNP with MIF further improves prognostic capability.
Electrochemically Reduced Polycrystalline Tin Oxide Thin Films: Surface Analysis and Electroplated Copper Adhesion (1996)

In previously reported work, a conductivity enhancement effect in polycrystalline tin oxide thin films, which are widely used for the front electrodes in flat panel displays, has been achieved by electroplating copper onto the 300 nm high sidewalls of the electrode. Recent experiments show that if an electrolytic reduction is introduced as a surface modification process just before electroplating then excellent adhesion between copper and tin oxide can be achieved. In this paper, the chemical, physical and surface morphological changes of tin oxide electrodes have been characterized by using atomic force microscopy, x‐ray diffraction, x‐ray photoelectron spectroscopy, and surface sheet resistance measurements by a four‐point probe method. The electrolytic reduction was found to result in an increase in the intensity of the x‐ray reflection from the (110) planes of tin oxide, and compositional nonuniformity of the tin oxide surface layers, where metallic tin is trapped at the surface, and oxygen is enriched in the subsurface region. These results, taken together, suggest that the observed adhesion improvement may be due to a combination of tin oxide surface roughening due to preferential etching and the increased (110) orientation, in situ cleaning, and chemical bonding introduced by surface chemical changes.
Heteroduplex DNA Correction in <i>Saccharomyces cerevisiae</i> Is Mismatch Specific and Requires Functional <i>PMS</i> Genes (1989)

In vitro-constructed heteroduplex DNAs with defined mismatches were corrected in Saccharomyces cerevisiae cells with efficiencies that were dependent on the mismatch. Single-nucleotide loops were repaired very efficiently; the base/base mismatches G/T, A/C, G/G, A/G, G/A, A/A, T/T, T/C, and C/T were repaired with a high to intermediate efficiency. The mismatch C/C and a 38-nucleotide loop were corrected with low efficiency. This substrate specificity pattern resembles that found in Escherichia coli and Streptococcus pneumoniae, suggesting an evolutionary relationship of DNA mismatch repair in pro- and eucaryotes. Repair of the listed mismatches was severely impaired in the putative S. cerevisiae DNA mismatch repair mutants pms1 and pms2. Low-efficiency repair also characterized pms3 strains, except that correction of single-nucleotide loops occurred with an efficiency close to that of PMS wild-type strains. A close correlation was found between the repair efficiencies determined in this study and the observed postmeiotic segregation frequencies of alleles with known DNA sequence. This suggests an involvement of DNA mismatch repair in recombination and gene conversion in S. cerevisiae.
Intracorneal Lens Implantation (1983)

In previous experiments, we found that a high-water-content hydroxyethyl methacrylate (Permalens) hydrogel implant was not only well tolerated within the rabbit corneal stroma but also would successfully alter the anterior radius of curvature, and thus the refractive state, of the rabbit eye. The same lens material implanted in the cornea of a patient with aphakic bullous keratopathy was tolerated for six months and decreased epithelial edema but did not alter the refractive state. This cornea, containing the intrastromal lens, was obtained at subsequent penetrating keratoplasty and studied by light and transmission electron microscopy. Morphologically, the epithelium and anterior stroma were not edematous, whereas the stroma posterior to the lens remained edematous. Minimal fibroblastic activity was evident at the lens-stroma interface. There were no signs of inflammation, ulceration, or neovascularization.
Asparagine amide metabolism in developing cotyledons of soybean (1981)

Magic-angle single and double cross-polarization (13)C and (15)N NMR spectra have been obtained of lyophilized soybean cotyledons cultured on media containing, as the only nitrogen source, [4-(13)C, amide-(15)N]asparagine. Single cross-polarization NMR shows directly and unambiguously that both labels from asparagine are incorporated extensively and nonrandomly into protein by the developing cotyledon during a 2-week period. A stable-isotope double label tags a chemical bond. The metabolic fate of the asparagine double label was followed by double cross-polarization NMR using the latter's sensitivity to the dipolar coupling between directly bonded (13)C and (15)N. These experiments show that in culture the direct incorporation of asparagine (with no scrambling of label) accounts for about half of all asparagine residues in soybean protein. This conclusion implies the operation of a regulatory apparatus in soybeans for both direct utilization and degradation of asparagine in protein synthesis.
Comparison of clinical staging algorithms and111Indium-capromab pendetide immunoscintigraphy in the prediction of lymph node involvement in high risk prostate carcinoma patients (1999)

These data suggest that the PPVs for the clinical predictive algorithms are similar and that the PPV of the radiolabeled monoclonal antibody scan alone or in combination with the algorithms has additional value in predicting lymph node involvement in prostate carcinoma patients at high risk of regional disease spread. These algorithms and the 111In-capromab pendetide scan may be used for the appropriate selection of candidates for definitive local therapy in men with clinically localized prostate carcinoma and significant risk of lymph node involvement.
Hitting the right level (2004)

The demands placed on emergency nurses continue to change, in terms not only of workload but also of the roles undertaken.
Evaluating fault trees (AND and OR gates only) with repeated events (1990)

It is pointed out that a common practice in the evaluation of large fault trees is to truncate the computation by neglecting high-order or low-probability cutsets. A major disadvantage of most simple truncation methods, however, is that their accuracy is indeterminate because they do not establish rigorous bounds on the combined probability of the neglected cutsets. A truncated with residuals algorithm is presented. It uses probability-based truncation and determines a rigorous upper bound on each event-probability by propagating the effect of all the truncated cutsets in the form of numeric residuals. The method applies only to fault trees constructed entirely of AND and OR gates and allows unrestricted use of repeated events.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
CRYSTALLINE PEPSIN (1931)

In Vol. 13, No. 6, July 20, 1930, page 743, line 24, for "Millon" read "Molisch."
Factors influencing detection of <scp>eDNA</scp> from a stream‐dwelling amphibian (2013)

Environmental DNA (eDNA) methods for detecting and estimating abundance of aquatic species are emerging rapidly, but little is known about how processes such as secretion rate, environmental degradation, and time since colonization or extirpation from a given site affect eDNA measurements. Using stream-dwelling salamanders and quantitative PCR (qPCR) analysis, we conducted three experiments to assess eDNA: (i) production rate; (ii) persistence time under different temperature and light conditions; and (iii) detectability and concentration through time following experimental introduction and removal of salamanders into previously unoccupied streams. We found that 44-50 g individuals held in aquaria produced 77 ng eDNA/h for 2 h, after which production either slowed considerably or began to equilibrate with degradation. eDNA in both full-sun and shaded treatments degraded exponentially to <1% of the original concentration after 3 days. eDNA was no longer detectable in full-sun samples after 8 days, whereas eDNA was detected in 20% of shaded samples after 11 days and 100% of refrigerated control samples after 18 days. When translocated into unoccupied streams, salamanders were detectable after 6 h, but only when densities were relatively high (0.2481 individuals/m(2) ) and when samples were collected within 5 m of the animals. Concentrations of eDNA detected were very low and increased steadily from 6-24 h after introduction, reaching 0.0022 ng/L. Within 1 h of removing salamanders from the stream, eDNA was no longer detectable. These results suggest that eDNA detectability and concentration depend on production rates of individuals, environmental conditions, density of animals, and their residence time.
Inhibition of Rotavirus Replication by Prostaglandin A: Evidence for a Block of Virus Maturation (1998)

Rotaviruses are recognized as the leading cause of severe viral gastroenteritis in young children and in immunocompromised patients. Cyclopentenone prostaglandins possess antiviral activity against several single-strand RNA viruses; therefore, the effect of prostaglandin A1 (PGA1) on SA-11 simian rotavirus infection was investigated in cultured cells. PGA1 potently inhibited SA-11 rotavirus replication. Whereas it did not affect virus adsorption or penetration, PGA1 partially inhibited VP4 and VP7 synthesis and selectively reduced glucosamine incorporation into the NSP4 viral enterotoxin. Electron microscopy analysis showed that, despite normal formation of cytoplasmic inclusions and budding of particles into the rough endoplasmic reticulum, virus maturation was impaired in PGA1-treated cells, with most of the virus particles remaining in the membrane-enveloped intermediate form. Because prostaglandins are used clinically as cytoprotective drugs for gastric ulcers, these observations offer new perspectives in the search for therapeutic agents for rotavirus-induced gastroenteritis.
Psychosomatic disorders (1989)

Convinced that many physical ailments are directly linked to an emotional problem, the authors provide an in-depth explanation of somatic illness and the various methods of treating it. They outline the roles and responsibilities of nurses working in a multidisciplinary context.
Feline Neural Progenitor Cells II: Use of Novel Plasmid Vector and Hybrid Promoter to Drive Expression of Glial Cell Line-Derived Neurotrophic Factor Transgene (2012)

Sustained transgene expression is required for the success of cell transplant-based gene therapy. Most widely used are lentiviral-based vectors which integrate into the host genome and thereby maintain sustained transgene expression. This requires integration into the nuclear genome, and potential risks include activation of oncogenes and inactivation of tumor suppressor genes. Plasmids have been used; however lack of sustained expression presents an additional challenge. Here we used the pCAG-PyF101-eGFP plasmid to deliver the human GDNF gene to cat neural progenitor cells (cNPCs). This vector consists of a CAGG composite promoter linked to the polyoma virus mutant enhancer PyF101. Expression of an episomal eGFP reporter and GDNF transgene were stably maintained by the cells, even following induction of differentiation. These genetically modified cells appear suitable for use in allogeneic models of cell-based delivery of GDNF in the cat and may find veterinary applications should such strategies prove clinically beneficial.
Combining Single-Version and Evolutionary Dependencies for Software-Change Prediction (2007)

The paper advocates the need for the investigation and development of a software-change prediction methodology that combines the change sets estimated from software dependency analysis (via single-version analysis) and the actual change sets found in software version histories (via multiple-version analysis). Traditionally prescribed methodologies such as Impact Analysis (IA) are based on the former, whereas a more recent methodology, mining software repository (MSR), is based on the latter. The research hypothesis is that combining these two methodologies will result in an overall improved support for software-change prediction.
Ki-67, cyclin D1, p53 and bcl-2 expression in advanced head and neck cancer. (2003)

In order to analyse the radiosensitivity of tumours and to evaluate the possibility of improving the treatment results with regard to genetic alterations, we examined 33 patients with advanced head and neck tumours after 66-70 Gy irradiation. Between 1998 and 2001, 33 patients with advanced head and neck squamous cell carcinoma (HN-SCC) were observed. They received 66-70 Gy to the primary tumour site and pathological lymph nodes. One month later, physical examination and CT were performed to verify the effect of radiotherapy, and the patients were followed until their death. The histological grading and Ki-67, cyclin D1, p53 and bcl-2 status were examined from the aspect of their potential prognostic value in all patients. The average survival was 13 months; 25% of the patients survived for at least 20 months. Seventy-two percent of the patients demonstrated Ki-67 positivity, 69% p53 positivity and 40% cyclin D1 positivity; there were only 12% bcl-2-positive cases. A significant correlation was not found between the tumour response or the duration of survival and the Ki-67, p53 or cyclin D1 positivity. Only bcl-2-positive cases exhibited significantly better outcome. These parameters indicate the proliferating (Ki-67 and cyclin D1) and apoptotic (p53 and bcl-2) activities of advanced HN-SCC cells. Our results proved that they proliferate rapidly and have impaired repair or apoptotic functions. The heterogeneity of our results did not allow us to conclude that the above parameters are of clinically reliable prognostic value, but the obviously high kinetic activity of HN-SCC underlines the potential efficacy and need for accelerated irradiation in these cases.
Investigation of ground and object motions at the TV tower in Sopron, Hungary (2001)

The investigation of the coupling between building and ground motions is of great importance because the results contribute to the planning of stable, motionproof constructions and to forecast of damages. For monitoring ground and building motions the TV tower in Sopron, Hungary was chosen. Two borehole tiltmeters, Applied Geomechanics Inc., model 722A were used for continuous and short-term high frequency tilt measurements. One of the instruments was installed on the concrete basement of the TV tower and the other in a borehole drilled at a distance of about 90 m beside the tower. This paper presents continuous data series of a length of more than one year, high frequency tilt measurements with sampling rates of up to 10 Hz and discusses the first experiences of the observations.
Analysis of site-specific N-glycosylation of recombinant <i>Desmodus rotundus</i> salivary plasminogen activator rDSPAα1 expressed in Chinese hamster ovary cells (1997)

The recombinant plasminogen activator (rDSPA alpha 1) from the vampire bat Desmodus rotundus is a promising new thrombolytic agent that exhibits a superior pharmacological profile if compared to tissue-type plasminogen activator (t-PA) or streptokinase. In the present study the structures of the carbohydrate moieties at the two N-glycosylation sites (Asn-117, Asn-362) of rDSPA alpha 1 expressed in Chinese hamster ovary cells were determined. N-Linked glycans were enzymatically released from isolated tryptic glycopeptides by peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase F digestion and separated by two-dimensional HPLC. Oligosaccharide structures were characterized by analysis of carbohydrate composition and linkage, by mass spectrometry, and by sequence analysis in which the fluorescently labeled glycans were cleaved with an array of specific exoglycosidases. More than 30 different oligosaccharides were identified. The results revealed that Asn-117 carried a mixture of one high-mannose structure (17% of site-specific glycosylation), three hybrid glycans (26%) and predominantly biantennary complex N-glycans (54%). Glycosylation site Asn-362 was found to comprise complex glycans with biantennary (50%), 2,4- and 2,6-branched triantennary (21%, 11%), and tetraantennary structures (10%), which were fucosylated at the innermost residue of N-acetylglucosamine. Mainly neutral and monosialylated glycans, and smaller quantities of disialylated glycans, were detected at both glycosylation sites. Sialic acid was alpha 2-3 linked to galactose exclusively. As shown in this study the N-glycans attached to Asn-117 of rDSPA alpha 1 are more processed during biosynthesis than the high-mannose structures linked to Asn-117 of t-PA, to which the polypeptide backbone of rDSPA alpha 1 is structurally closely related.
Blown Cellulose Fiber Thermal Insulations: Part 2—Thermal Resistance (1978)

The thermal resistance of a number of commercial blown loose-fill cellulose fiber thermal insulations has been measured using the guarded hot plate and heat flowmeter methods. An equation describing the variation of thermal resistance with temperature, temperature difference, density, and thickness has been derived from these measurements and, with lesser precision, from the data provided by other investigators. The equation does not include the effects of chemical content, moisture content, chemical composition, or structure of the paper particles. The thermal resistance of a layer of insulation was found not to be directly proportional to thickness. The equation for thermal resistance fits the National Research Council of Canada (NRC) data with a standard deviation of less than 3.5 percent for thickness of 50 to 305 mm.
Proteases in Biology And Medicine (2002)

The ubiquitin-proteasome pathway of intracellular proteolysis matrix metalloproteinases in cancer proteolytic processing of the amyloid &-protein precursor of Alzheimer's disease caspases methionine aminopeptidases and angiogenesis precursor convertases in the secretory pathway, cytosol and extracellular millieu proteases in blood clotting anatomy and pathology of HIV-1 protease, the perfect model peptidase inhibition of the peptidases (ACE and NEP) in control of blood pressure shedding of membrane proteins by ADAM family proteases regulated intramembrane protelysis - from the ER to the nucleus protease-activated receptors - the role of cell-surface proteolysis in signalling mining proteases in the genome databases.