gebhart/patrepeval huggingface dataset:
A Concept for Public Access to Privately Operated Cooperating Local Access Points (2005)

For many future mobile communication scenarios, the traditional operators are believed to be unable or unwilling to support some services, mainly for cost reasons. Thus, there are always gaps in the coverage and capacity of these systems. This paper describes a non-conventional and low-cost concept for wireless access using privately operated local access points (LAPs) contributing to the public access, thus adding coverage and capacity in, for example, homes, offices and public hotspots. The work has been performed in the EU-funded ambient networks (AN) project. A migration path is presented, starting with today's LAPs for private-use-only to LAPs for public use, implementing the AN objective of "access for anyone to any network". The main contributions in the paper are: 1) the identification and analysis of re-use of fixed and wireless transport and access capacity using ad hoc mesh networks between LAPs and 2) the use of network advertising & discovery for LAP concepts.
Nearly 100% Triplet Harvesting in Conventional Fluorescent Dopant‐Based Organic Light‐Emitting Devices Through Energy Transfer from Exciplex (2015)

Nearly 100% triplet harvesting in conventional fluorophor-based organic light-emitting devices is realized through energy transfer from exciplex. The best C545T-doped device using the exciplex host exhibits a maximum current efficiency of 44.0 cd A(-1) , a maximum power efficiency of 46.1 lm W(-1) , and a maximum external quantum efficiency of 14.5%.
Closing the gap between ASIC and custom (2000)

We investigate the differences in speed between application-specific integrated circuits and custom integrated circuits when each are implemented in the same process technology, with some examples in 0.25 micron CMOS. We first attempt to account for the elements that make the performance different and then examine ways in which tools and methodologies may close the performance gap between application-specific integrated circuits and custom circuits.
Quantitative magnetization transfer imaging via selective inversion recovery with short repetition times (2007)

Quantitative magnetization transfer imaging (qMTI) methods are able to estimate fundamental sample parameters, such as the relative size of the solid-like macromolecular proton pool and the spin exchange rate between this pool and the directly measured free water protons. One such method is selective inversion recovery (SIR), in which the free water protons are selectively inverted and the signal is fit to a biexponential function of the inversion time (TI). SIR uses only low-power pulses and requires no separate RF (B1) or static field (B0) field maps, and the analysis is largely independent of the macromolecular pool lineshape. These are all advantages over steady-state off-resonance saturation qMTI methods. However, up to now, SIR has been implemented only with repetition times TR>>T1. This paper describes a modification of SIR with smaller TR values and a greater signal-to-noise ratio (SNR) efficiency.
Idazoxan and Response to Typical Neuroleptics in Treatment-Resistant Schizophrenia (1996)

The antagonism of alpha 2 receptors augmented therapeutic response to typical neuroleptic treatment in treatment-resistant patients with schizophrenia. This antagonism may contribute to clozapine's superior antipsychotic effects.
Site-specific activation of the alternative pathway of complement. Synthesis of a hybrid molecule consisting of antibody and cobra venom factor. (1986)

Cobra venom factor (CoF) is an analog of the activated third component of human complement (C3b). Unlike C3b, CoF is completely resistant to inactivation by factors H and I, the endogenous control proteins of the alternative pathway of complement. This property makes CoF a useful reagent when unrestricted activation of complement is desired. CoF was covalently conjugated to the IgG fraction of rabbit antihuman erythrocyte antiserum, and the ability of the hybrid molecules to initiate activation of the alternative pathway at a specific site was tested. The hybrid molecules were heterogeneous polymers (CoFn-IgGn, where n is an integer greater than 1 for at least one of the components), and both components retained their individual functional activities. The alternative-pathway C3/C5 convertase complex was formed by adding purified factors B and D to the hybrid in the presence of magnesium. This complex (antibody-CoFBb) was able to bind to erythrocytes and activate both C3 and C5. Activation of C5 initiated formation of the potentially cytolytic membrane attack complex of complement on the surface of the cell. When used in combination with rabbit serum, the hybrid molecule was a potent mediator of complement-induced hemolysis. The decay kinetics of the hybrid C3/C5 convertase complex when bound to normal human erythrocytes were not first order, but 40% of the activity remained after 3.5 h at 37 degrees C. Conjugation of CoF to specific antibodies will permit investigation of the consequences of alternative-pathway activation at selective sites. These hybrids may also have therapeutic potential.
Human Factors Analysis of an ICU (1998)

The safe, effective and consistent use of medical devices requires that they be technically capable of achieving their desired functions, and that they be designed to address the potential for user problems that may arise during their use. While the issue of usability arises throughout the hospital, the intensive care unit has been shown to be an area with unique human factors problems. The reasons for this include the multiple devices often being used, the stress under which the staff works, and the condition of the patients that may make them more susceptible to device mishaps. To investigate this issue we examined the ICU at a local hospital for potential causes of human error. Our observations revealed a range of problems, including: multiple alarm use; excessive clutter; anthropo-metric limits; and the potential for confusion in the various interfaces between devices, disposables, and patients. Our investigation also included discussions with the nursing staff and a survey to see how they feel about the medical equipment they use. As a result of these investigations, several recommendations for in-house and manufacturer improvements are given.
The role of the PHEX gene (PEX) in families with X-linked hypophosphataemic rickets (1998)

For over a hundred years, the bane of rickets (a disease of bone), has been prominent in those countries that have participated in, and seeded, the industrial revolution. Industrialisation had major effects of the demography of populations, and many people moved to dark, heavily industrialised cities to find work. It soon became apparent that rickets could be cured by supplementing the diet with cod liver oil and exposure to sunlight. This in turn led to the discovery that photoactivation of 7-dehydrocholesterol was required to produce vitamin D, an indispensable regulator of bone mineral metabolism. Although inadequate exposure to light and poor dietary intake are the main causes of rickets and osteomalacia, recent research has confirmed the role of familial, and tumour forms of the disease. This review will describe the recent advances in our knowledge of the molecular defects in X-linked hypophosphataemic rickets (HYP), and oncogenic hypophosphataemic osteomalacia (OHO). Although HYP and OHO have different primary defects, both diseases have similarities that suggest a linked or overlapping pathophysiology. Also, without doubt, the recent cloning of the gene defective in HYP (the PHEX gene), has given researchers a new reagent to explore the molecular regulation of bone and its links to kidney endocrine function. The fact that the PHEX gene codes for a Zn metallopeptidase raises new and intriguing questions, and adds new momentum to the research on diseases of bone mineral metabolism.
Catheter ablation of atrial fibrillation: do we know what we are doing? (2007)

Although atrial fibrillation (AF) represents the most common arrhythmia that is seen in every day cardiology practice, 1-3 the surgeons, and not the cardiologists, were the first to take the initiative for its radical cure.Cox and colleagues 4,5 developed the Maze procedure and its modifications in the 80s followed by the pioneering attempt of Swartz et al. 6 to ablate the arrhythmia in the electrophysiology laboratory in 1994.Now, catheter ablation is an established therapeutic option for certain patients with AF.Several ablation strategies have emerged which, although extremely diverse, report similar success rates, in the range of 60-80%, with 30-40% of patients followed for a year or two having had two procedures, however, different endpoints and methodology of assessment of AF recurrence make interpretation of success rather difficult. 7It is of interest that despite the considerable clinical experience and accumulated evidence from experimental data, the exact mechanism of eliminating AF by catheter ablation techniques is still unknown.
Content and Composition of Free Sterols and Free Fatty Alcohols in Jojoba Oil (1997)

A method was developed for the isolation and identification of phytosterols and fatty alcohols in jojoba oil. The method consists in the separation of these compounds from wax esters in the oil by means of an aluminum oxide column followed by further fractionation of the minor components by column chromatography on silica gel. The 4-demethylsterols, 4-methylsterols, triterpene alcohols (4,4-dimethylsterols), and fatty alcohols are identified by means of their gas chromatographic and mass spectrometric data. The present paper includes a method for the quantitation of the free sterols in jojoba oil. Keywords: Plant; alcohol; sterol; lipid; Simmondsia
Molecular identification and genetic variation of Alternaria species isolated from tomatoes using ITS1 sequencing and inter simple sequence repeat methods (2019)

The sequencing of ITS1 led to the identification of <i>Alternaria</i> species that are morphologically similar. The production of various mycotoxins by <i>A</i> <i>.</i> <i>Alternata</i> species leads to the contamination of livestock and human food. Regarding this, the investigation of the genetic diversity of <i>A. alternata</i> species using the ISSR marker would facilitate the identification of suitable and effective strategies for controlling the fungal and mycotoxin contamination of human nutrition.
Electron Distribution in GaAs as Revealed by the X-Ray Diffraction (1970)

An X-ray study with CuKα was carried out on a fine-powder sample of GaAs. Relative intensities of 11 lines from the 111 to the 620 were measured and the scale factor was determined from absolute intensities of the 111 and the 220. Form the three-dimensional difference Fourier synthesis on the (110) plane, two sorts of peaks were found in Δ ρ ( x , y , z ). One lies near (1/8, 1/8, 1/8), which is the midpoint of chemical bond between Ga and As. This peak seems to correspond to a covalent bond. The other lies near (1/2, 1/2, 1/2), which is the position of anions in the NaCl structure with a cation at the origin. It may be possible that this latter peak corresponds to the ionicity of the bond.
The Isomerization of <i>n</i>-Butenes over Acidic Ion-exchange Resin (1972)

Abstract The isomerization of n-butenes and the polymerization of propylene were studied in a gas-phase reaction on a sulfonic acid-type resin catalyst. These reactions were considered to proceed via the carbonium ion formation on the functional groups, and a strong correlation was found between the activities in these two reactions. The acidity and the acid strength of the resin catalyst were measured by means of amine titration in a nonpolar solvent using Hammett indicators. The value of the acidity obtained at pKa=6.8 seemed to correspond to the number of the ion-exchangeable hydrogen on the functional groups. The effects of poisoning by ion exchange with Na+, Mg2+ or by adsorption of NH3 were also studied. The decrease in the activity for the isomerization was not proportional to the amount of cations exchanged. The catalytic activities of the protonic hydrogen seemed not to be equal as was suggested by the result of resin catalysts in polar solvents. The possible heterogeneity of the active sites on the resin catalyst was discussed. The six relative rate constants were calculated on the basis of the mutual interconversion among the three isomers of n-butene. The apparent energy of activation for the double-bond migration of 1-butene was found to be 17 kcal/mol on the H-form resin, but it was changed by ion exchange with Na+. The selectivities were characteristic of solid acid catalysts of the protonic type.
A Prototype of A New Dynamic Focusing Lens with kHz Order Response (2002)

近年, lkllzのフレームレートで画像を取得・処理できる高速視覚システムが注目されている。一方, 光学系のうち, 合焦機構やズーム機構といった可動部分の多くは高速視覚システムのフレームレートに比べて非常に低速(1-10Hz程度)であり, 光学系を利用した画像処理には速度の点で大きな制限が存在していた。本発表では, 1kHz以上の応答速度をもつ可変焦点レンズを提案し, 特に応答速度の検証を目的とした試作について説明する。そして, 実験から提案した構造が実際に1kHz以上の応答速度を持つことを示す。
Explosives detection using quantum cascade laser spectroscopy (2013)

An infrared spectroscopy based explosives detection system using a quantum cascade laser (QCL) as excitation source was used to record mid infrared spectral signals of highly energetic materials (HEM) deposited on real world substrates such as travel baggage, cardboard and wood. The HEMs used were nitroaromatic military explosive trinitrotoluene (TNT), aliphatic nitrate ester pentaerythritol tetranitrate (PETN) and aliphatic nitramine hexahydrotrinitrotriazine (RDX). Various deposition methods including sample smearing, spin coating, spray deposition and partial immersion were evaluated for preparing samples and standards used as part of the study. Chemometrics statistical routines such as principal component analysis (PCA) regression with various preprocessing steps were applied to the recorded infrared spectra of explosives deposited as trace contaminants on target substrates. The results show that the dispersive infrared vibrational technique investigated using QCL is useful for detection of HEMs in the types of substrates studied.
Persistent delayed‐type hypersensitivity reaction to injectable non‐animal‐stabilized hyaluronic acid (2007)

Injectable hyaluronic acid can be associated with a variety of complications including immediate and delayed-type hypersensitivity reactions. Physicians should be familiar with products used in other countries, as patients may present for evaluation following adverse reaction to fillers obtained abroad or from American physicians using non-FDA-approved products.
Beam-Lead Technology (1966)

A process has been developed to batch-fabricate beam-lead transistors, integrated circuits, and other components, where the leads serve a structural and protective as well as electrical function. Platinum silicide ohmic contacts, titanium and platinum sputtered layers, and electroformed gold beam leads constitute the metallurgical structure of the devices described. Test transistors have survived 350°C aging for hundreds of hours in corrosive ambients, and centrifuging at 135,000 g's.
Characteristics of Amino Acids (1996)

This appendix presents useful basic information, including common abbreviations, useful measurements and data, characteristics of amino acids and nucleic acids, information on radioactivity and the safe use of radioisotopes and other hazardous chemicals, conversions for centrifuges and rotors, characteristics of common detergents, and common conversion factors.
EMG-based simultaneous and proportional estimation of wrist/hand kinematics in uni-lateral trans-radial amputees (2012)

We propose a method for estimating wrist kinematics during dynamic wrist contractions from multi-channel surface electromyography (EMG). The algorithm extracts features from the surface EMG and uses dedicated multi-layer perceptron networks to estimate individual joint angles of the 3 degrees of freedom (DoFs) of the wrist. The method was designed with the aim of proportional and simultaneous control of multiple DoFs of active prostheses by unilateral amputees. Therefore, the proposed approach was tested in both unilateral transradial amputees and in intact-limbed control subjects. It was shown that the joint angles at the 3 DoFs of amputees can be estimated from surface EMG recordings , during mirrored bi-lateral contractions that simultaneously and proportionally articulated the 3 DoFs. The estimation accuracies of amputee subjects with long stumps were 62.5% ± 8.50% across all 3 DoFs, while accuracies of the intact-limbed control subjects were 72.0% ± 8.29%. The estimation results from intact-limbed subjects were consistent with earlier studies. The results from the current study demonstrated the feasibility of the proposed myoelectric control approach to provide a more intuitive myoelectric control strategy for unilateral transradial amputees.
Anle138b Partly Ameliorates Motor Deficits Despite Failure of Neuroprotection in a Model of Advanced Multiple System Atrophy (2016)

The neurodegenerative disorder multiple system atrophy (MSA) is characterized by autonomic failure, cerebellar ataxia and parkinsonism in any combination associated with predominantly oligodendroglial α-synuclein (α-syn) aggregates (glial cytoplasmic inclusions = GCIs). To date, there is no effective disease modifying therapy. Previous experiments have shown that the aggregation inhibitor anle138b reduces neurodegeneration, as well as behavioral deficits in both transgenic and toxin mouse models of Parkinson's disease (PD). Here we analyzed whether anle138b improves motor skills and reduces neuronal loss, as well as oligodendroglial α-syn aggregation in the PLP-α-syn transgenic mouse challenged with the mitochondrial toxin 3-nitropropionic acid (3-NP) to model full-blown MSA. Following 1 month of treatment with anle138b, MSA mice showed signs of motor improvement affecting stride length, but not pole, grip strength, and beam test performance. Loss of dopaminergic nigral neurons and Purkinje cells was not attenuated and GCI density remained unchanged. These data suggest that the pathology in transgenic PLP-α-syn mice receiving 3-NP might be too advanced to detect significant effects of anle138b treatment on neuronal loss and intracytoplasmic α-syn inclusion bodies. However, the partial motor amelioration may indicate potential efficacy of anle138b treatment that may be mediated by its actions on α-syn oligomers or may reflect improvement of neuronal dysfunction in neural at risk populations. Further studies are required to address the efficacy of anle138b in transgenic α-syn models of early-stage MSA and in the absence of additional toxin application.
CONDENSATION OF PHENOLS AND NAPHTHOLS WITH STYRENE (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCONDENSATION OF PHENOLS AND NAPHTHOLS WITH STYRENENG. PH. BUU-HOÏ, HENRI LE BIHAN, and FERNAND BINONCite this: J. Org. Chem. 1952, 17, 2, 243–248Publication Date (Print):February 1, 1952Publication History Published online1 May 2002Published inissue 1 February 1952https://pubs.acs.org/doi/10.1021/jo01136a011https://doi.org/10.1021/jo01136a011research-articleACS PublicationsRequest reuse permissionsArticle Views330Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Levetiracetam as an Adjunctive Analgesic in Neoplastic Plexopathies (2005)

Certain types of pain associated with cancer may be difficult to treat with standard therapies, often resulting in intractable pain and suffering for the patient. The use of an opioid as analgesic monotherapy can lead to poorly controlled pain as well as multiple side effects. Non-opioid adjunctive analgesics, such as antidepressants and antiepileptic drugs (AEDs) often improve both pain control, and side effect prevalence. Levetiracetam is an AED with unique mechanisms of action that may have analgesic properties in various pain syndromes. Seven patients with neoplasms involving neural structures (four invading the brachial plexus, and three the lumbosacral plexus) had severe pain of 8 to 9 out of 10 on a visual analog scale (VAS), despite the use of parenteral opioids and various adjunctive therapies. These patients were treated with oral levetiracetam titrated over days to two weeks, depending on the location of pain, drug response, and tolerance to tapering of opioid analgesics. Opioid and adjunctive analgesic use and VAS scores were recorded periodically. The maximum levetiracetam dose ranged from 500 mg to 1500 mg BID. All patients experienced pain control improvement after the addition of levetiracetam, with VAS scores decreasing from 8-9 out of 10 to 0-3 out of 10 within two to 14 days of therapy initiation. Overall opioid use decreased by at least an estimated 70%, without drug related adverse events. In this small series of patients, levetiracetam effectively and safely improved pain relief in patients with neoplastic plexopathies previously resistant to standard analgesic approaches.
HLA‐DR expression by platelets in acute idiopathic thrombocytopenic purpura (1992)

Induction of expression of MHC class II antigens on the surface of cells that do not ordinarily express these proteins has been implicated in the pathogenesis of autoimmunity in diabetes mellitus and autoimmune thyroiditis. Platelets express class I but not class II HLA antigens. In this report, we describe a child with acute idiopathic thrombocytopenic purpura who at the time of the thrombocytopenic episode had class II (HLA-DR) antigens on his platelets. Following recovery, the HLA-DR antigens were no longer present on the platelets. We postulated that class II had been induced on his megakaryocytes by a cytokine such as interferon gamma, and that the induced expression of class II antigens contributed to the autoimmune disorder. To substantiate this possibility we next studied class I and II antigen expression on an erythroleukaemia cell line (HEL), which has many megakaryocytic features. Following treatment of HEL cells with interferon gamma, class I expression was increased and HLA-DR antigens were induced. These observations suggest that cytokine-mediated induced HLA-DR expression may contribute to the pathogenesis of a subset of thrombocytopenias.