gebhart/patrepeval huggingface dataset:
A Consideration of Mechanical Methods of Preventing Bedsores in Elderly Patients (1964)

Research Articles| October 02 2009 A Consideration of Mechanical Methods of Preventing Bedsores in Elderly Patients Subject Area: Geriatrics and Gerontology Mary R. Bliss Mary R. Bliss From the Whittington Hospital, London Search for other works by this author on: This Site PubMed Google Scholar Gerontologia Clinica (1964) 6 (1): 10–21. https://doi.org/10.1159/000244803 Article history Published Online: October 02 2009 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Mary R. Bliss; A Consideration of Mechanical Methods of Preventing Bedsores in Elderly Patients. Gerontologia Clinica 1 January 1964; 6 (1): 10–21. https://doi.org/10.1159/000244803 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsGerontologia Clinica Search Advanced Search Article PDF first page preview Close Modal 1964Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Dynamics of Wetting Revisited (2009)

We present new spreading-drop data obtained over four orders of time and apply our new analysis tool G-Dyna to demonstrate the specific range over which the various models of dynamic wetting would seem to apply for our experimental system. We follow the contact angle and radius dynamics of four liquids on the smooth silica surface of silicon wafers or PET from the first milliseconds to several seconds. Analysis of the images allows us to make several hundred contact angle and droplet radius measurements with great accuracy. The G-Dyna software is then used to fit the data to the relevant theory (hydrodynamic, molecular-kinetic theory, Petrov and De Ruijter combined models, and Shikhmurzaev's formula). The distributions, correlations, and average values of the free parameters are analyzed and it is shown that for the systems studied even with very good data and a robust fitting procedure, it may be difficult to make reliable claims as to the model which best describes results for a given system. This conclusions also suggests that claims based on smaller data sets and less stringent fitting procedures should be treated with caution.
Platinum-catalyzed hydrosilylation of alkynes (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPlatinum-catalyzed hydrosilylation of alkynesLarry N. Lewis, Karen G. Sy, Garold L. Bryant Jr., and Paul E. DonahueCite this: Organometallics 1991, 10, 10, 3750–3759Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://doi.org/10.1021/om00056a055Request reuse permissionsArticle Views2739Altmetric-Citations140LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Microspectrometric insights on the uptake of antibiotics at the single bacterial cell level (2015)

Bacterial multidrug resistance is a significant health issue. A key challenge, particularly in Gram-negative antibacterial research, is to better understand membrane permeation of antibiotics in clinically relevant bacterial pathogens. Passing through the membrane barrier to reach the required concentration inside the bacterium is a pivotal step for most antibacterials. Spectrometric methodology has been developed to detect drugs inside bacteria and recent studies have focused on bacterial cell imaging. Ultimately, we seek to use this method to identify pharmacophoric groups which improve penetration, and therefore accumulation, of small-molecule antibiotics inside bacteria. We developed a method to quantify the time scale of antibiotic accumulation in living bacterial cells. Tunable ultraviolet excitation provided by DISCO beamline (synchrotron Soleil) combined with microscopy allows spectroscopic analysis of the antibiotic signal in individual bacterial cells. Robust controls and measurement of the crosstalk between fluorescence channels can provide real time quantification of drug. This technique represents a new method to assay drug translocation inside the cell and therefore incorporate rational drug design to impact antibiotic uptake.
Synthesis and Thermolysis of 2<i>H</i>-1,2,3-Benzothiadiazine 1,1-Dioxide and 2,1-Benzoxathiin-3-one 1,1-Dioxide (1971)

2H-1,2,3-Benzothiadiazine 1,1-dioxide (6) and 2,l-benzoxathiin-3-one 1,1-dioxide (5), representatives of little-known heterocyclic systems, have been synthesized from sodium o-formylbenzenesulfonate (7). Thermolysis of 5 and 6 was investigated in the hope of finding evidence for the formation of a sulfene. No characterized product was obtained from 5, but 6 gave the sultine 3H-2,1-benzoxathiole 1-oxide (21), the compound expected from the sulfene 20.
Maximum Likelihood and Maximum A Posteriori Direction-of-Arrival Estimation in the Presence of SIRP Noise (2016)

The maximum likelihood (ML) and maximum a posteriori (MAP) estimation techniques are widely used to address the direction-of-arrival (DOA) estimation problems, an important topic in sensor array processing. Conventionally the ML estimators in the DOA estimation context assume the sensor noise to follow a Gaussian distribution. In real-life application, however, this assumption is sometimes not valid, and it is often more accurate to model the noise as a non-Gaussian process. In this paper we derive an iterative ML as well as an iterative MAP estimation algorithm for the DOA estimation problem under the spherically invariant random process noise assumption, one of the most popular non-Gaussian models, especially in the radar context. Numerical simulation results are provided to assess our proposed algorithms and to show their advantage in terms of performance over the conventional ML algorithm.
Quantification and excretion kinetics of a magnetic resonance imaging contrast agent by capillary electrophoresis‐mass spectrometry (2009)

A novel method for the analysis of Gadolinium-based contrast agents in complex clinical matrices is presented. Three commonly applied ionic contrast agents for magnetic resonance imaging were separated by CE and detected by ESI-MS. Blank urine samples were spiked with Dotarem (Gd-DOTA, Gadolinium-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), Magnevist (Gd-DTPA, Gadolinium-diethylenetriaminepentaacetic acid) and Multihance (Gd-BOPTA, Gadolinium-benzyloxymethyl-diethylenetriaminepentaacetic acid) to determine the recovery rates. The figures of merit were determined with LODs as low as 2.0 x 10(-7) mol/L for Gd-DOTA, 5.0 x 10(-7) mol/L for Gd-DTPA and 1.0 x 10(-6) mol/L for Gd-BOPTA. The respective LOQs were 6.6 x 10(-7) mol/L for Gd-DOTA, 1.5 x 10(-6) mol/L for Gd-DTPA and 3.3 x 10(-6) mol/L for Gd-BOPTA. The linear working range comprised two orders of magnitude starting at the LOQ, with regression coefficients of R > or = 0.999 for all investigated analytes. Using this CE-MS method, Gd-DOTA was quantified in seven urine samples obtained at different times after delivery from a volunteer magnetic resonance imaging patient who was treated with Dotarem. Additionally, total Gd concentrations were determined by means of ICP-optical emission spectroscopy to validate the CE-MS data. To compensate for dietary dilution effects of the urine samples, creatinine was determined by HPLC with UV/Vis absorption detection. Gd-DOTA concentrations were normalized to urinary creatinine, illustrating the fast excretion kinetics of Gd-DOTA.
Web Performance Tuning (1998)

From the Publisher:
As long as the Web has existed, people have been trying to make it faster. The maturation of the Web has meant more users, more data, and more features -- and consequently, longer waits. Improved performance has become a critical factor in determining the usability of the Web in general, and of individual sites in particular. Web Performance Tuning is about getting the best possible performance from the Web. This book isn't just about tuning web server software; it's also about streamlining web content, getting optimal performance from a browser, tuning both client and server hardware, and maximizing the capacity of the network itself.
Web Performance Tuning hits the ground running, providing concrete advice for quick results: the blunt instruments for improving crippled performance right away. The book then shifts gears to provide a conceptual background of the principles of computing performance. The latter half of the book examines each element of a web transaction -- from client to network to server -- to find the weak links in the chain and show how to strengthen them. In addition, the book includes many more examples and graphs of real-world performance problems and their solutions, and has been updated for Java 2. Web Performance Tuning is for anyone who has waited too long for a web page to display, or watched the servers they manage slow to a crawl. It's about making the Web more usable for everyone.
Technical implementation and evaluation of a bioelectrical breast scanner (1988)

Impedance measurements can be used to visualize the distribution of resistivity inside human body. Using arrays of electrodes allows images to be reconstructed. The examination of the breast using an automated examination bank has been realized. The electrodes are moved by pneumatic jacks. This technique both reduces the examination time and ensures a more regular electrode geometry than by manual operation. The final electrode positioning is controlled by the operator and can be easily adjusted. Thirty-two electrodes are shared by sixteen current sources and sixteen differential voltmeters. Due to capacitive properties of the tumors of the breast and the need for reference values, the data are collected at two frequencies. The system described is noninvasive and of relatively low cost.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Triply Nested Ocean Model for Simulating the Kuroshio—Roles of Horizontal Resolution on JEBAR (2003)

A triply nested ocean general circulation model was used to examine how the model horizontal resolution influences the Kuroshio in the East China Sea (ECS) and the sea level variability. As the model resolution increases from 1/2° to 1/18° the path, current intensity, and vertical structure of the model Kuroshio and the variability of sea level become closer to observations. In general, the higher-resolution model improves the baroclinic as well as barotropic component of the Kuroshio and thus reproduces more realistic density and current fields. This improvement, in addition to better representation of topography, results in better reproduction of the interaction between baroclinicity and bottom topography, that is, JEBAR (joint effect of baroclinicity and bottom relief) in a high-resolution model. Modeling the Kuroshio in the ECS provides an ideal example of such improvement. In particular, the Kuroshio veering phenomenon at (30°N, 129°E) southwest of Kyushu is discussed, together with the seasonal meridional migration of the path. It is shown that JEBAR and advection of the geostrophic potential vorticity are two major contributions to the vorticity balance in this area. The summer intensification of JEBAR resulting from the intensified stratification yields a strong offshore volume transport across the shelf break, thereby leading to the southward shift of the veering latitude. In winter, the weakened JEBAR, combined with the increased wind stress curl, decreases the offshore volume transport in a considerable amount, explaining the northward shift of the veering latitude. The present reproduction of seasonal migration of the Kuroshio axis at 129°E is in good agreement with observation.
Photocatalytic reduction of CO2 with H2O: significant enhancement of the activity of Pt–TiO2 in CH4 formation by addition of MgO (2013)

Photocatalytic activity in the reduction of CO(2) with H(2)O to CH(4) was significantly enhanced by simply adding MgO to TiO(2) loaded with Pt. A positive correlation between CH(4) formation activity and basicity was observed. The interface between TiO(2), Pt and MgO in the trinary nanocomposite played a crucial role in CO(2) photocatalytic reduction.
[Treatment of pilonidal sinus with excision and primary suture using a local, resorbable antibiotic carrier. Results of a prospective randomized study]. (1992)

The excision of a pilonidal sinus with wound healing by second intention, often results in a long duration of treatment. On the other hand, primary suture after excision has a high rate of abscess formation. In a randomized study we treated 40 patients with excision of pilonidal sinus, insertion of a collagen sponge containing Gentamicin and primary suture (group 1) to prevent this abscess formation. Another 40 patients were treated in the same way but without applying the Gentamicin-collagen sponge (group 2). There had been no significant differences as to the history and duration of the disease, the wound size, the degree of inflammation, the weight of the patients or the amount of hair near the sinus. In group 1 only 7.5% of the patients had a postoperative abscess formation, in contrast to group 2, with an abscess rate of 52.5% and consecutive surgery (p less than 0.001). One year after the operation the recurrence rate was 0 in both groups. Considering the results mentioned, surgical excision of the pilonidal sinus in combination with insertion of a resorbable antibiotic sponge we recommend this therapy.
Excited-state dynamics of porphyrin–naphthalenediimide–porphyrin triads (2012)

The excited-state dynamics of two triads consisting of a naphthalenediimide (cNDI) substituted at the core by two zinc (ZnP) or free-base tetraphenylporphyrins (FbP) was investigated by ultrafast fluorescence and transient absorption spectroscopy. The electronic absorption spectra of the triads are almost the composites of those of the constituents, pointing to a weak electronic coupling and to a localization of the excitation energy on one of the porphyrins. In cyclohexane, the excited-state dynamics of the triads are essentially the same as those of the individual porphyrins, with the exception of the Soret emission of the ZnP triad, whose lifetime exhibits a more than 10 fold shortening compared to ZnP. A similarly ultrafast fluorescence decay was measured in tetrahydrofuran and benzonitrile. In these two solvents, charge separation from the excited porphyrin to the cNDI was found to take place with ∼1 ps and ∼25 ps time constants in the ZnP and FbP triads, respectively. The build up of the charge-separated state population in the ZnP triad is independent of the excitation wavelength, indicating that charge separation takes place from the lowest singlet excited state. Charge recombination occurs with a time constant of around 8 ps in both triads, i.e. it is slower than charge separation in the ZnP triad but faster in the FbP triad. These differences are rationalized in terms of the driving forces for charge separation and recombination.
Infrastructure to vehicle communications using inductive loops (2014)

Road safety is a worldwide issue. The constant increase of the number of vehicles and the more congested infrastructure lead to more traffic incidents. Infrastructure to vehicle communication is a way to improve traffic safety, by sending traffic information to vehicles, such as the colour the next traffic light will be when the car reaches the road junction. This approach may be useful also for autonomous vehicles that need all the data available in order to travel in a safe manner on the road network. In this article we shall analyse the possibility of sending information from the traffic management system to vehicles using one of the most common traffic detectors, the inductive loop. Language: en
Heme Degradation as Catalyzed by a Recombinant Bacterial Heme Oxygenase (Hmu O) from Corynebacterium diphtheriae (1999)

Hmu O, a heme degradation enzyme in the pathogen Corynebacterium diphtheriae, catalyzes the oxygen-dependent conversion of hemin to biliverdin, carbon monoxide, and free iron. A bacterial expression system using a synthetic gene coding for the 215-amino acid, full-length Hmu O has been constructed. Expressed at very high levels in Escherichia coli BL21, the enzyme binds hemin stoichiometrically to form a hexacoordinate high spin hemin-Hmu O complex. When ascorbic acid is used as the electron donor, Hmu O converts hemin to biliverdin with alpha-hydroxyhemin and verdoheme as intermediates. The overall conversion rate to biliverdin is approximately 4-fold slower than that by rat heme oxygenase (HO) isoform 1. Reaction of the hemin-Hmu O complex with hydrogen peroxide yields a verdoheme species, the recovery of which is much less compared with rat HO-1. Reaction of the hemin complex with meta-chloroperbenzoic acid generates a ferryl oxo species. Thus, the catalytic intermediate species and the nature of the active form in the first oxygenation step of Hmu O appear to be similar to those of the mammalian HO. However, the considerably slow catalytic rate and low level of verdoheme recovery in the hydrogen peroxide reaction suggest that the active-site structure of Hmu O is different from that of its mammalian counterpart.
Skin secretions of Rana saharica frogs reveal antimicrobial peptides esculentins-1 and -1B and brevinins-1E and -2EC with novel insulin releasing activity (2006)

Skin secretions of Rana saharica were evaluated for the isolation and characterisation of novel insulinotropic peptides. Crude secretions obtained from young adult frogs by mild electrical stimulation of the dorsal skin surface were purified by reverse phase HPLC yielding 80 fractions. In acute 20-min incubations with glucose responsive BRIN-BD11 cells, fractions 36-43, 46-54 and 57-63 significantly stimulated insulin release by 2- to 8-fold compared with 5.6 mM glucose alone. Pooled fractions in the latter two bands were rechromatographed to reveal 9 homogenous peaks, which elicited significant 1.3- to 3.5-fold increases in insulin release (P < 0.05). Structural analysis of the most potent non-toxic peptides was performed by mass spectrometry and automated Edman degradation. This revealed four major insulin-releasing peaks with molecular masses of 2,676.9 Da, 3,519.3 Da, 4,920.4 Da and 4,801.2 Da respectively. These peptides were found to be identical to brevinin-1E, brevinin-2EC, esculentin-1 and esculentin-1B, which belong to the group of antimicrobial peptides isolated from skin secretions of various Rana frog species. Preliminary studies on the mechanism underlying the insulinotropic actions of esculentins-1 and -1B suggested possible involvement of both cyclic AMP-protein kinase A and -C-dependent G-protein sensitive pathways. These data indicate that the skin secretions of Rana saharica frogs contain bioactive molecules with significant insulin-releasing activity. Relatives of the brevinin/esculentin peptide family merit further investigation as novel insulin secretagogues.
An improved three-phase stepped-voltage inverter (1980)

The paper Presents an improved method of generating a three-phase stepped-voltage waveform using ten thyristor power switches. In the proposed method, it is possible to generate one step for every 20 ° of the voltage waveform on all the phases. The waveform has a total harmonic distortion of about 10% and the Predominant harmonies are the 17th and 19th. This is possible by a unique method of magneticcoupling betweena 120° conduction three-phase bridge inverter and a triple frequency single phase bridge inverter. The theoretical results are in close agreement with experimental results.
Differentiation of Serum Antibodies from Pigs Vaccinated or Infected with Aujeszky's Disease Virus by a Competitive Enzyme Immunoassay (1986)

A competitive enzyme immunoassay was developed to detect antibodies to a glycoprotein (gI) of Aujeszky's disease virus. Infected cell monolayers were used as antigen and a monoclonal antibody directed against an epitope of gI as indicator antibody. It was demonstrated that pigs vaccinated with the Bartha, BUK or NIA-4 strains did not produce antibody to the epitope of gI, whereas all wild-type viruses tested did induce this antibody. The antibody to the gI epitope persisted for at least 15 weeks. The present test, which enables us to distinguish pigs vaccinated with certain attenuated strains from pigs infected with wild-type Aujeszky's disease virus, may be of great value in future combined vaccination-eradication programmes for Aujeszky's disease.