gebhart/patrepeval huggingface dataset:
Installation and operation of the Southwire 30-meter high-temperature superconducting power cable (2001)

Southwire Company has installed, tested and is operating the first real-world application of a high-temperature superconducting cable system at its headquarters in Carrollton, GA, USA. The cable is powering three Southwire manufacturing plants, marking the first time a company has successfully made the difficult transition front laboratory to practical field application of an HTS cable. The cables are rated at 12.4-kV, 1250-A, 60 Hz and are cooled with pressurized liquid nitrogen at temperatures from 70-80 K. Before placing the cables into service, extensive offline electrical testing was performed including voltage withstand, measurement of DC critical current, extended load current testing, rated voltage testing and partial discharge measurement. The cables were energized on Jan. 5, 2000 for online testing and operation, and by the end of August 2000, had provided 100% of the customer load for 2164 hours.
Synthesis and characterization of single-wall carbon nanotube–amorphous diamond thin-film composites (2002)

Thin-film single-wall carbon nanotube (SWNT) composites synthesized by pulsed laser deposition (PLD) are reported. Ultrahard, transparent, pure-carbon, electrically insulating, amorphous diamond thin films were deposited by PLD as scratch-resistant, encapsulating matrices for disperse, electrically conductive mats of SWNT bundles. In situ resistance measurements of the mats during PLD, as well as ex situ Raman spectroscopy, current–voltage measurements, spectroscopic ellipsometry, and field-emission scanning electron microscopy, are used to understand the interaction between the SWNT and the highly energetic (∼100 eV) carbon species responsible for the formation of the amorphous diamond thin film. The results indicate that a large fraction of SWNT within the bundles survive the energetic bombardment from the PLD plume, preserving the metallic behavior of the interconnected nanotube mat, although with higher resistance. Amorphous diamond film thicknesses of only 50 nm protect the SWNT against wear, providing scratch hardness up to 25 GPa in an optically transmissive, all-carbon thin-film composite.
Physical Tests of Flour Quality (1940)

Crop Production/Industries, Research and Development/Tech Change/Emerging Technologies, Research Methods/Statistical Methods
AFC1, a LAMMER kinase from Arabidopsis thaliana, activates STE12-dependent processes in yeast. (1994)

In the yeast Saccharomyces cerevisiae a kinase cascade activates the transcription factor STE12 leading to mating in haploid cells and pseudohyphal growth in diploid cells. To investigate related signal transduction pathways in higher plants, we have isolated a putative protein kinase gene from Arabidopsis thaliana that restores STE12-dependent functions to yeast with mutations in this signal transduction pathway. This Arabidopsis gene, AFC1, induces three STE12-dependent processes even in signal transduction-defective yeast strains: mating-specific gene expression in haploid yeast, mating of haploid yeast to yield diploids, and pseudohyphal growth in diploid yeast. AFC1 has no effect on transcription of the STE12 gene and, instead, is likely to activate the STE12 protein. However, AFC1 has only limited homology to FUS3 and KSS1, the endogenous yeast kinase regulators of STE12. AFC1 is a member of a recently described CDC2-related kinase subfamily, the LAMMER kinases. A close AFC1 homolog, AFC2, lacks STE12 activation phenotypes, indicating the specificity of AFC1. The phenotypes of AFC1 in yeast provide us with tools to elucidate the role of this kinase in Arabidopsis.
Abstract IA04: ATRX mutations in human carcinogenesis (2013)

Abstract The recent years, genome-wide analyses identified the genetic landscapes of many different tumor types. One of the most frequent class of genes found to be mutated were genes whose products regulate epigenetic mechanisms, like chromatin modification and remodeling, providing a link between genetic alterations and epigenetic changes in cancer. One of these genes is ATRX. This gene has been studied in the context of alpha thalassemia-mental retardation X-linked syndrome. In human sporadic solid tumors, it was first shown to be mutated in pancreatic neuroendocrine tumors (PanNETs). Approximately, 50% of PanNETs had mutations in either ATRX or DAXX. The proteins of these two genes form a complex that deposits H3.3 at heterochromatin and telomeres. ATRX, but not DAXX, has also been found to be mutated in certain types of central nervous system tumors. The prevalence of mutations in ATRX is different for the different types of gliomas. It is mutated more frequently in astrocytomas and oligoastrocytomas, but rarely in primary glioblastomas. Recently, we identified mutations in the promoter of TERT in the same set of glioma samples. TERT mutations were more prevalent in primary glioblastomas and oligodendrogliomas. Overall, mutations in ATRX and TERT were mutually exclusive, suggesting that these two genetic mechanisms result in equivalent growth advantages. Mutations in ATRX have almost perfect correlation with Alternative Lengthening of Telomeres (ALT) phenotype in PanNETs, CNS tumors and other cases with ATRX mutations, thus, TERT activation and ALT phenotype are mutually exclusive. This has implications for understanding the relationship between telomeres and tumorigenesis. These studies, in addition to providing clues about the underlying genetic changes that drive tumorigenesis, they also have clinical implications. Mutations in ATRX or DAXX in PanNETs associate with better prognosis. Mutations of ATRX and TERT aid in the classification and prognostication of brain tumors. Further understanding of the role of ATRX in tumorigenesis should help in uncovering new ways for therapeutic targeting of tumors with mutations in this gene. Citation Format: Nickolas E. Papadopoulos. ATRX mutations in human carcinogenesis. [abstract]. In: Proceedings of the AACR Special Conference on Chromatin and Epigenetics in Cancer; Jun 19-22, 2013; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2013;73(13 Suppl):Abstract nr IA04.
Gene expression of CD24 core peptide molecule in developing brain and developing non‐neural tissues (1993)

CD24 is a signal transducing molecule on the surface of most human B cells, murine immature T cells, myeloid and erythroid lineage cells. We isolated rat CD24 gene from embryonic brain cDNA library and characterized the gene expression during rat embryogenesis. Rat CD24 cDNA is homologous to murine and human CD24 gene with respect to the structure of signal peptide, N-glycosylation sites, and possible glycosyl phosphatidylinositol (GPI) linker attaching site, suggesting that rat CD24 is a transducing glycoprotein anchoring membrane via GPI linker. In the developing embryo, in situ hybridization analyses revealed that CD24 transcript was detected in primitive ectoderm, mesoderm, and ventral endoderm of day 9 postcoitum (p.c.) embryo. In central nervous systems CD24 transcript was strongly expressed in postmitotic cells of spinal cord, hindbrain, midbrain, and forebrain from day 11 p.c. embryo to day 21 p.c. embryo but was dramatically down regulated in adult brain. Furthermore, expression was also detected in epithelium during development of non-neural tissues, such as intestinal mucosal epithelium, nasal epithelium, ductal epithelium of salivary gland, bronchial epithelium, renal tubular epithelium, and hair follicles. In tooth development, where correct epithelium requires epithelial-mesenchymal interactions, CD24 mRNA was specifically induced in mesenchymal cells differentiating into odontoblast in dental papilla, suggesting the pivotal role of CD24 molecule in cell differentiations in vivo. We suggest that CD24 gene may encode the core peptide molecule of 31 kDa GPI linked molecule which has been known to be important in the migration of neurons on astroglial processes during development.
Identification and Funtional Characterization of Three Postsynaptic Short-chain Neurotoxins from Hydrophiinae, Lapemis hardwickii Gray. (2001)

Three cDNA clones, sn12, sn36 and sn160, encoding isoforms of postsynaptic short-chain neurotoxins, were cloned by screening a cDNA library of the venom from Hydrophiinae, Lapemis hardwickii Gray. The sequences of three cDNA clones encoded proteins consisting of 60 amino acid residues. There was only one amino acid substitution among the three isoforms SN12, SN36 and SN160 at the position 46 of mature proteins, and they were Pro(46), His(46) and Arg(46), respectively. The three molecules were expressed in Escherichia coli and the recombinant proteins were characterized. Different LD(50) were obtained, namely 0.0956 mg/kg, 0.3467 mg/kg and 0.2192 mg/kg, when the SN12, SN36 and SN160 were injected into Kunming mice(i.p.). In analgesic effect assayed by the acetic acid-induced writhing method, SN12 and SN160 showed similar analgesic effect, but SN36 had effects significantly different with the other two. Our studies suggested that the amino acid residues on position 46 could affect the combination between the postsynaptic short-chain neurotoxins and the nicotinic acetylchoine receptor, since different amino acid substitution resulted in different biological activities.
Novel Cytostatic Lanostanoid Triterpenes from <i>Ganoderma australe</i> (2003)

Abstract Two new compounds 1 and 2 , together with the known sterols ergosterol, 5,6‐dehydroergosterol, and ergosterol peroxide, and four polyoxygenated lanostanoid triterpenes named applanoxidic acid A ( 3 ), C ( 4 ), F ( 5 ), and G ( 6 ) were isolated from the fungus Ganoderma australe. The structures of the new compounds were elucidated by means of spectroscopic techniques, while the known triterpenoids 3 – 6 were identified by comparing their spectral data with those reported in the literature. Compounds 1 – 6 inhibited the viability and growth of the HL‐60 cell line.
Evidence for sperm limitation in the blue crab, Callinectes sapidus (2003)

Reproductive success of female blue crabs may be limited by the amount of sperm received during the female's single, lifetime mating. Sperm must be stored in seminal receptacles until eggs are produced and fertilized months to years after mating. Further, intense fishing pressure impacts male abundance, male size and population sex ratio, which affect ejaculate quantity. We measured temporal variation in seminal receptacle contents in relation to brood production for two stocks differing in both fishing pressure on males and latitudinal effects on reproductive season: Chesapeake Bay, Maryland and Virginia, experienced intensive fishing and relatively short reproductive season; and the Indian River Lagoon, Florida, experienced lower exploitation and longer reproductive season. Nearly all (>98%) females were mated, and mating prevalence did not vary among sites during 1996. Seminal receptacle weight declined markedly for 2 mo following mating as seminal fluid disappeared to leave only spermatophores for long-term storage, which suggests that seminal fluid serves as a short-term sperm plug. Seminal receptacle weight in upper Chesapeake Bay declined by 31 % from 1992-1999, indicating that females received smaller ejaculates. In 1996, seminal receptacle contents were highest (3.75 g wet wt, 2.3 x 10(3) mug DNA, 1.2 x 10(9) sperm) in Florida, but were significantly lower by: 25% for weight and 50% for sperm number at the upper Chesapeake Bay site; and 30% for weight and 65% for sperm number at lower Chesapeake Bay sites. Generally, females receive 2-3 x 10(3) spermatophores and 10(8)-10(9) sperm cells for a full ejaculate, whereas females produce ca. 3 x 10(6) eggs per brood. Chesapeake Bay females appear to live about 3.5 yr, producing 1-3 broods (up to 9 x 10(6) eggs) per year and up to 6-7 broods (2.1 x 10(7) eggs) per lifetime. In contrast, Florida crabs produced up to 6-7 broods (2.1 X 101 eggs) per year. and up to 18 broods (5.4 x 10(7) eggs) per lifetime. In Florida, last broods produced by lab-held females were often infertile, indicating that females became sperm limited at the end of their lifetime. Experiments showed that male mating history affected female reproductive success, with females mated late in a sequence having only one third the brood hatching success of females mated early in the sequence. Sperm : egg ratios were estimated at 100: 1 to 400:1 for the first brood but only about 20:1 or 30:1 for maximum lifetime broods over 2 seasons, suggesting that about 67 x 10(6) sperm are used per brood of 3 x 10(6) eggs. A model of brood production and sperm depletion in blue crabs indicates that sperm limitation may be common in Florida as females age, and in Chesapeake Bay as a result of fishery-induced reductions in initial quantities of sperm transferred at mating.
Integrating real-time and partial-order information in event-data displays (1994)

The events occurring in the execution of a distributed or parallel application are related by a partial, rather than a total, order. Wehave developed prototype software that collects such events during program execution and produces a graphical display consistent with the partial order. Such a display can be very helpful in understanding and debugging distributed and parallel applications. However, using only partial-order information does not allow the performance characteristics of an application to be understood. Integrating real-time information with the partial order can provide a display that is useful for understanding both functional and performance aspects of the application. An algorithm is required to adjust the collected real-time information, to ensure that real times are consistent with the partial order. Lamport&apos;s clock algorithm provides such an adjustment, but can significantly distort the real-time values. It was necessary to develop a more complex algorithm, using the same basic principles, that minimises such distortions. We have extended existing prototype software for displaying event data, so that either a purely partial-order display or a real-time displaymay be obtained. The real-time facilities can be used in multiple target environments, such as OSF/DCE, Hermes, and SR.
Synthesis and properties of starch-g-poly(maleic anhydride-co-vinyl acetate) (2009)

Starch-g-poly(maleic anhydride-co-vinyl acetate) (SMV) was synthesized via the esterification reaction of starch with the copolymer of maleic anhydride and vinyl acetate. The carboxylic unit percentage (CUP) of SMV was tailored with reaction conditions, and it ranged from 29.8 to 46.9%. The structure and the morphology of the copolymers were characterized with Fourier Transform Infrared spectroscopy and X-ray diffraction analysis. It was found that SMV could form complex with some metal cations such as Ca 2+ , Pb 2+ and Hg 2+ or cationic polyelectrolyte chitosan, and precipitate from the solution. The weight of precipitation increases with an increase of the CUP of SMV. In addition, a physically cross-linked hydrogel of SMV/poly(vinyl alcohol) (PVA) was obtained by freeze/thaw technique. Scanning electron microscopy exhibited the hydrogel was uniform. The gel exhibited pH-responsive re-swelling. The maximum swelling-ratio values of SMV/PVA (9:1, wt/wt) gel were 3.29 and 5.34 in HCl (pH 1.0) and phosphate-buffer saline (PBS) (pH 12) respectively.
BASE: An Acid Alternative (2008)

Web applications have grown in popularity over the past decade. Whether you are building an application for end users or application developers (i.e., services), your hope is most likely that your application will find broad adoption and with broad adoption will come transactional growth. If your application relies upon persistence, then data storage will probably become your bottleneck.
Purification and properties of <i>Klebsiella aerogenes</i> <scp>d</scp>-arabitol dehydrogenase (1979)

An Escherichia coli K12 strain was constructed that synthesized elevated quantities of Klebsiella aerogenes D-arabitol dehydrogenase; the enzyme accounted for about 5% of the soluble protein in this strain. Some 280 mg of enzyme was purified from 180 g of cell paste. The purified enzyme was active as a monomer of 46,000 mol.wt. The amino acid composition and kinetic constants of the enzyme for D-arabitol and D-mannitol are reported. The apparent Km for D-mannitol was more than 3-fold that for D-arabitol, whereas the maximum velocities with both substrates were indistinguishable. The enzyme purified from the E. coli K12 construct was indistinguishable by the criteria of molecular weight, electrophoretic mobility in native polyacrylamide gel and D-mannitol/D-arabitol activity ratio from D-arabitol dehydrogenase synthesized in wild-type K. aerogenes. Purified D-arabitol dehydrogenase showed no immunological cross-reaction with K. aerogenes ribitol dehydrogenase. During electrophoresis in native polyacrylamide gels, oxidation by persulphate catalysed the formation of inactive polymeric forms of the enzyme. Dithiothreitol and pre-electrophoresis protected against this polymerization.
Design of Bulk Thermoelectric Modules for Integrated Circuit Thermal Management (2006)

Various parameters affecting the performance of bulk thermoelectric (TE) modules used for integrated circuit (IC) thermal management are studied. An effective circuit model is developed that takes into account various ideal and nonideal effects in the module. It is shown that there is an optimum module thickness and an optimum operating current which depend on the overall heat dissipation and on the external thermal resistances. Optimized TE modules with ZT~0.8, will have a cross section over leg length ratio of 0.037m, can increase the chip operation power by 15% in comparison with the case without a TE cooler while maintaining the chip temperature below 100degC. This is for a package thermal resistance of 0.2K/W. Prospects for TE material with higher ZT values and the effect of contact resistance on the power dissipation density are also discussed. The results presented in this paper can be used in applications other than in the IC thermal management when external thermal resistances dominate the performance of TE modules
Asymmetric high temperature superconducting Josephson vortex-flow transistors with high current gain (1995)

We have fabricated Josephson vortex-flow transistors (JVFTs) based on asymmetric parallel arrays of YBa2Cu3O7−δ bicrystal grain boundary junctions. The critical current Ic and the voltage V at fixed bias current Ib were measured as a function of the control current Ictrl through a control line inductively coupled to the array. For JVFTs with an asymmetric in-line geometry a high current gain g=∂Ic/∂Ictrll ranging between about 20 at 40 K and 14 at 70 K was achieved. This current gain is much higher than that obtained for symmetric devices and results from the self-field effect of the electrode currents. In contrast to the current gain the transresistance rm=∂V/∂Ictrl of the JVFTs could not be enhanced by an asymmetric device structure. The current-voltage characteristics of the asymmetric JVFTs show pronounced step-like structures caused by the self-field of the electrode currents.
Fabrication of High-Mobility Nitrided Hafnium Silicate Gate Dielectrics with Sub-1-nm Equivalent Oxide Thickness Using Plasma Nitridation and High-Temperature Postnitridation Annealing (2006)

Changes in optical thickness and equivalent oxide thickness (EOT) during postdeposition annealing (PDA) and postnitridation annealing (PNA) were investigated to fabricate sub-1-nm-EOT nitrided hafnium silicate (HfSiON) gate dielectrics. In spite of optical thickness reductions by PDA, none of the PDA conditions could reduce the EOT and bring about the merit in leakage current reduction. On the other hand, high-temperature PNA without oxygen was found to be effective for reducing both optical thickness and EOT. Furthermore, leakage current reduction ratio and effective mobility were improved by applying high-temperature PNA. Consequently, the fabrication of 0.81-nm-EOT HfSiON gate dielectrics with a gate leakage current of 0.74 A/cm2 at 0.7 V and an electron mobility of 235 cm2/(V s) at 0.8 MV/cm (76% of SiO2) has been realized.
A kinetic mass balance model for 1,5-anhydroglucitol: applications to monitoring of glycemic control (1997)

The polyol 1,5-anhydroglucitol (AG) present in human plasma is derived largely from ingestion and is excreted unmetabolized. Reduction of plasma [AG] has been noted in diabetics and is due to accelerated excretion of AG during hyperglycemia. Plasma [AG] has therefore been proposed as a marker for glycemic control. A precise understanding of its utility relies on a quantitative understanding of the mass balance for AG. In this study, non-steady-state data from the literature were analyzed to develop a dynamic mass balance model for AG that is based on the two-compartment model proposed by Yamanouchi et al. [T. Yamanouchi, Y. Tachibana, H. Akanuma, S. Minoda, T. Shinohara, H. Moromizato, H. Miyashita, and I. Akaoka. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E268-E273, 1992]. The data are consistent with a model in which exchange between tissue and plasma pools is rapid and in which the tissue compartment mass is two to three times the mass of the plasma compartment. According to model estimates, accelerated excretion of AG due to hyperglycemia can cause marked net depletion of total AG over a time scale of days. Recovery from a depleted state is slow because the total body capacity represents >5 wk of normal intake. Accordingly, AG monitoring should be able to indicate the presence of past glucosuric hyperglycemic episodes during a period of days to weeks, as well as provide information on the extent to which high deviations from the average plasma glucose concentration are operative.
Supercritical Fluids:  Introduction (1999)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTSupercritical Fluids: IntroductionRyoji NoyoriView Author Information Nagoya UniversityCite this: Chem. Rev. 1999, 99, 2, 353–354Publication Date (Web):January 22, 1999Publication History Published online22 January 1999Published inissue 1 February 1999https://pubs.acs.org/doi/10.1021/cr980085ahttps://doi.org/10.1021/cr980085aeditorialACS PublicationsCopyright © 1999 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views5608Altmetric-Citations141LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (16 KB) Get e-AlertscloseSUBJECTS:Chemical reactions,Fluids,Inhomogeneity,Liquids,Solvents Get e-Alerts