gebhart/patrepeval huggingface dataset:
Development of Coffea canephora Pierre ex A. Froehner transplants cultivated in different substrates and containers (2010)

In coffee transplant production, substrate is one of the factors limiting growth. The ideal substrate should meet the oxygen, water and nutrient requirements for normal plant growth. The objective of this work was to verify the effect of different substrates and containers on the growth of coffee transplants in the nursery, and also to develop a new methodology for producing Coffea canephora Pierre ex A. Froehner transplants using agroindustrial residues. The following containers were used: polyethylene bags, conical tubettes with 80 cc and 120 cc capacity and pressed blocks (mixture of organic material). Each treatment corresponded to one type of substrate and one type of container. The results showed that organic material may be a potential substrate for C. canephora transplant production. The transplants produced in the organic material, organic material + controlled nutrients, soil + cow manure + controlled nutrients substrates presented the best results for all the traits compared, in relation to the other substrates, indicating that they are the best option for producing coffee transplants. The pressed block, polyetilene bags and big size tubettes may be appropriate containers for C. canephora transplant production. The commercial substrate was inadequate for coffee transplant production, regardless of the container.
Oxidative cyclisation of ketone thiosemicarbazones. Part II. Derivatives of phenoxyacetone (1970)

Oxidative cyclisation of phenoxyacetone (4-phenyl)thiosemicarbazone to 5-methyl-5-phenoxymethyl-4-phenyl-Δ1-1,2,4-triazoline-3-thione was accompained by a rearrangement giving 3-mercapto-5-methyl-1-phenoxy-methyl-4-phenyl-1,2,4-triazolinium hydroxide inner salt. Proof of structure was afforded by synthesis of 3-methyl-1-phenoxymethyl-4-phenyl-Δ2-1,2,4-triazoline-5-thione, 3-methyl-5-phenoxymethylthio-4-phenyl-1,2,4-triazole, and 2-methyl-2-phenoxymethyl-5-phenylimino-Δ3-1,3,4-thiadiazoline.
EDUCAÇÃO SUPERIOR E INTERNACIONALIZAÇÃO (2019)

As agendas mundiais aquiescentes ao processo de globalização econômica, ressignificações de blocos e territórios tem escalonado inúmeros eixos para a composição de um discurso e base ideológica anuentes ao processo de internacionalização, em tese, com forte ênfase à solidarização entre países economicamente avançados e àqueles abertos ao diálogo sob a mesma perspectiva. Ocorre que as proposições observados ao longo do tempo histórico, orientadas sob a lógica do mercado, não acontecem sem contrapartidas e/ou ganhos reais, ainda que em médio e longo prazos, logo, a “sintonia” possível deve necessariamente se materializar pela adesão ao sociometabolismo do arranjo social desejado.
Synthesis of pyrrolidine-2,4-diones(tetramic acids) and some derivatives (1972)

Pyrrolidine-2,4-dione (tetramic acid) has been obtained by heating its 3-ethoxycarbonyl derivative with water or nitromethane. Prolonged heating with water yields 4-hydroxy-3,4′-bi-Δ3-pyrrolinyl-2,2′-dione, the anhydro-derivative of the dione. 1- and 5-Methylpyrrolidine-2,4-diones and their anhydro-derivatives have been obtained similarly. Previously reported syntheses of these pyrrolidine-2,4-diones are shown to be in error; the products obtained appear to have been the corresponding anhydro-derivatives, or their hydrates. Other derivatives of the diones are described. Condensation of ethyl-4-hydroxy-2-oxo-Δ3-pyrroline-3-carboxylate with aromatic aldehydes yields mainly the (E)-5-arylmethylene derivatives.
Increased Synthesis of Spermidine as a Result of Upregulation of Arginase I Promotes Axonal Regeneration in Culture and<i>In Vivo</i> (2009)

Adult spinal axons do not spontaneously regenerate after injury. However, if the peripheral branch of dorsal root ganglion neurons is lesioned before lesioning the central branch of the same neurons in the dorsal column, these central axons will regenerate and, if cultured, are not inhibited from extending neurites by myelin-associated inhibitors of regeneration such as myelin-associated glycoprotein (MAG). This effect can be mimicked by elevating cAMP and is transcription dependent. The ability of cAMP to overcome inhibition by MAG in culture involves the upregulation of the enzyme arginase I (Arg I) and subsequent increase in synthesis of polyamines such as putrescine. Now we show that a peripheral lesion also induces an increase in Arg I expression and synthesis of polyamines. We also show that the conditioning lesion effect in overcoming inhibition by MAG is initially dependent on ongoing polyamine synthesis but, with time after lesion, becomes independent of ongoing synthesis. However, if synthesis of polyamines is blocked in vivo the early phase of good growth after a conditioning lesion is completely blocked and the later phase of growth, when ongoing polyamine synthesis is not required during culture, is attenuated. We also show that putrescine must be converted to spermidine both in culture and in vivo to overcome inhibition by MAG and that spermidine can promote optic nerve regeneration in vivo. These results suggest that spermidine could be a useful tool in promoting CNS axon regeneration after injury.
A Structural Framework for Deciphering the Link Between I-A <sup>g7</sup> and Autoimmune Diabetes (2000)

Susceptibility to murine and human insulin-dependent diabetes mellitus correlates strongly with major histocompatibility complex (MHC) class II I-A or HLA-DQ alleles that lack an aspartic acid at position β57. I-A g7 lacks this aspartate and is the only class II allele expressed by the nonobese diabetic mouse. The crystal structure of I-A g7 was determined at 2.6 angstrom resolution as a complex with a high-affinity peptide from the autoantigen glutamic acid decarboxylase (GAD) 65. I-A g7 has a substantially wider peptide-binding groove around β57, which accounts for distinct peptide preferences compared with other MHC class II alleles. Loss of Asp β57 leads to an oxyanion hole in I-A g7 that can be filled by peptide carboxyl residues or, perhaps, through interaction with the T cell receptor.
Real-time Animal Detection System for Intelligent Vehicles (2014)

Animal and Vehicle Collisions (AVCs) have been a growing concern in North America since the abundant wildlife resources and increases of automobiles. Such problems cause hundreds of people deaths, thousands of human injuries, billions of dollars in property damage and countless of wildlife deaths every year. To address these challenges, smart cars have to be equipped with Advanced Driver Assistance Systems (ADAS) able to detect dangerous animals (e.g., moose, elk and cow), which cross the road, and warn the driver about the imminent accident. In this thesis, we explore the performance of different image features and classification algorithms in animal detection application, and design a real-time animal detection system following three criteria: detection accuracy, detection time and system energy consumption. In order to pursue high detection rate but low time and energy consumption, a double-stage detection system is proposed. In the first stage, we use the LBP adopting AdaBoost algorithm which provides the next stage by a set of region of interests containing target animals and other false positive targets. Afterward, the second stage rejects the false positive ROIs by two HOG-SVM based sub-classifiers. To build and evaluate the animal detector, we create our own database, which will be updated by adding new samples. Through an extensive set of evaluations, we note that the double-stage system is able to detect about 85% of target animals.
Sustained delivery of lidocaine into the cochlea using poly lactic/glycolic acid microparticles (2009)

Lidocaine-loaded PLGA microparticles were shown to be capable of the sustained delivery of lidocaine into the cochlea, suggesting that they could be used for the attenuation of peripheral tinnitus.
A stereo matching algorithm using line segment features (2003)

A binocular-stereo-matching algorithm, based on a line matching method, which does not require the horizontal epipolar line constraint is presented. The method makes use of the line searching window determined by the epipolar lines of the extreme pixels of a given line segment and two circles whose radius is equal to the maximum possible disparity. The proposed algorithm was implemented on the KAISION-I system, designed for real-time image processing, and has been tested with various types of real scenes. The experimental results show that the proposed algorithm can be a useful tool for solving the correspondence problem in 3D computer vision.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Design and characterization of coherent integrated fiber-optic imaging probes (1994)

An integrated fiber-optic probe comprising a short length of multimode fiber that is fusion spliced to a monomode optical fiber has been fabricated for imaging and nonimaging applications. The fiber probe, typically 250 µm in diameter, can deliver a focused Gaussian spot approximately 25 µm in diameter at a distance of approximately 500 µm from the tip. Two off-the-shelf graded-index multimode fibers have been used in the fabrication of imaging and nonimaging probes. These integrated probes have considerably improved the spatial resolution of backscatter lensless fiber probes being utilized in the dynamic light-scattering characterization of colloidal suspension.
Derivation of Rate Constants for the Batch Furnace Radical Oxidation of Silicon Wafers via Hydrogen Combustion (2009)

Deal–Grove oxidation rate constants for the controlled combustion-based radical oxidation of silicon wafers in a batch reactor were determined, thus providing insight into the rate-limiting factors. Re-examination of the oxidation rates of wafers with different crystal orientations provides an estimate of the enhancement of the linear rate constant in radical oxidations as compared to standard wet and dry oxidation processes.
Multi-standard low-power DDR I/O circuit design in 7nm CMOS process (2017)

This paper presents novel circuit techniques to implement DDR I/O circuit design that can support multiple low-power standards in a state-of-art 7nm CMOS finfet process. Hybrid pull-up driver with a power gating switch is proposed to support a wide range of data rates and output swing levels. The usage of both thin and thick gate oxide devices in the final output stage effectively achieves minimal power consumption while enabling 6.4Gbps/pin data rate. The proposed input receiver directly converts the incoming signal's common mode levels to the optimal level of the 1st stage amplifier by a replica feedback loop. Frequency peaking technique is also employed to suppress the inter-symbol interference (ISI) and increase overall bandwidth of the receiver. Simulation results are provided.
Preparation of asialoglycoprotein receptor-mediated hepatic targeting nano- lipid ultrasound contrast agent and its ultrasound imaging in vitro (2011)

Objective To prepare the liver targeting nano-liquid perfluorocarbon ultrasound contrast agent and observe its general characteristics;to observe the targeting combined effects of the human liver cells L02 and the targeted ultrasound contrast agent ;to evaluate the gathering imaging effects of the targeted ultrasound contrast agent. Methods Amine method was used to prepared asialoglycoprotein Gal specific ligand polylysine (Gal-PLL), rotary evaporator and sonicated liquid fluorocarbon were used to prepare nano lipid ultrasound contrast agent. Human liver cell L02 were cultured, the combined effects were observed according to the reacting time of the cells and the targeted nano-lipid ultrasound contrast agent. The nanolipid ultrasound contrast agent and the degassed_ water_ were loaded into cysts and their ultrasound imaging effects were observed by ultrasound diagnostic apparatus Philips iU22. Results The particle size of the liquid fluorocarbon nano-targeted lipid ultrasound contrast agent was extremely small, uniform, cylindrical and spherical. The cysts in vitro showed that the side of the targeted liquid perfluorocarbon nano-lipid ultrasound contrast agent showed high echo. Conclusions The targeted liquid perfluorocarbon nano-lipid ultrasound contrast agent can be effectively targeted to the human liver cells L02 due to carrying home-made Gal-PLL. The targeted ultrasound contrast agents can be imaging by ultrasound and be confirmed in vitro.The size of the contrast agent was small, therefore, it can be considered an ideal ultrasonic molecular probe and achieve the ultrasound molecular imaging in cell level.

Key words: 
Ultrasonography;  Microbubbles;  Nanotechnology; Gene Targeting
Development of a novel noninvasive adhesive patch test for the evaluation of pigmented lesions of the skin (2014)

Our data suggest that mRNA molecular signatures can serve as a highly useful noninvasive method of differentiating melanoma from nevi and decrease the number of unnecessary biopsies.
Real-Time Document Image Super-Resolution by Fast Matting (2014)

From a single low resolution image, a real-time document image super-resolution algorithm is proposed to obtain high resolution document image with sharp text boundaries. First, a highly efficient document image matting algorithm based on local linear modeling is designed to decompose the input image into text, foreground and background layers, which contain the text edge information, the color information of the foreground and background respectively. Then the text layer is up-sampled with Teager filter to increase the sharpness of the text. For efficiency, the foreground and background layers are simply up-sampled through the bi-cubic interpolation. Finally, these three high resolution layers are composed to obtain the high-resolution image. Experiments on real scanned document images demonstrate the effectiveness of the proposed method in both visual perception and OCR performance
Centered vs. inferior off-center ablation to correct hyperopia and presbyopia. (1999)

Planned inferior off-center ablation to correct hyperopia and presbyopia achieved better distance and near visual acuity than centered ablation. As with centered ablation, no significant regression of effect occurred with off-center ablation; reading near vision was better and more stable with inferior off-center ablation.
Stereoradar Meteorology: A New Unified Approach to Process Data from Airborne or Ground-Based Meteorological Radars (1995)

The concept of stereoradar in meteorology was first proposed by Testud and Amayenc. It consists of radar observations of a precipitation cell from two viewing angles, using an attenuated frequency. The initial inspiration of the technique lays in the development of the ELDORA/ASTRAIA project, a dual-beam X-band airborne Doppler radar developed in common by NCAR and CRPE (Centre de Recherche en Physique de I”Environnement), and devoted to the observation of the three-dimensional dynamics of deep convection. At X band in severe weather the observed radar reflectivity may be severely corrupted by along-path attenuation. The stereoradar analysis was first conceived as a procedure to correct the observed reflectivity for attenuation. In July and August 1991, CRPE and NOAA collaborated to realize the first dual-beam airborne Doppler radar. Several scientific flights were accomplished in Florida in the framework of the CaPE (Convection and Precipitation/Electrification)experiment. These flights provide an excellent opportunity to validate the stereoradar concept on real data since (i) intense rain cells inducing strong X-band attenuation could be sampled by the dual-beam airborne radar, and (ii) ground truths were available from the three research radars (CP-2, CP-3, and CP-4) deployed on the ground by NCAR in CaPE. The object of this paper is to propose a new formulation for the stereoradar analysis that is simpler, more general, and numerically more stable than the previous one, because it implies now a first-order differentiation of the data field. The new processing is applied to a real dataset from the above-mentioned CaPE experiment. The first application to real data presented in this paper tends to demonstrate the great potential of this technique, not only to correct the apparent reflectivities for along-path attenuation but also to determine the specific attenuation field associated with a precipitation core. It should be emphasized that the stereoradar analysis achieves this retrieval without making any assumption about the size distribution or phase of the hydrometeors.
The Synthesis of Parathion and Some Closely Related Compounds (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of Parathion and Some Closely Related CompoundsJohn H. Fletcher, J. C. Hamilton, I. Hechenbleikner, E. I. Hoegberg, Beatrice J. Sertl, and J. T. CassadayCite this: J. Am. Chem. Soc. 1950, 72, 6, 2461–2464Publication Date (Print):June 1, 1950Publication History Published online1 May 2002Published inissue 1 June 1950https://pubs.acs.org/doi/10.1021/ja01162a028https://doi.org/10.1021/ja01162a028research-articleACS PublicationsRequest reuse permissionsArticle Views561Altmetric-Citations79LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Role for Gz in Pancreatic Islet β-Cell Biology (2005)

Glucose-stimulated insulin secretion and beta-cell growth are important facets of pancreatic islet beta-cell biology. As a result, factors that modulate these processes are of great interest for the potential treatment of Type 2 diabetes. Here, we present evidence that the heterotrimeric G protein G(z) and its effectors, including some previously thought to be confined in expression to neuronal cells, are present in pancreatic beta-cells, the largest cellular constituent of the islets of Langerhans. Furthermore, signaling pathways upon which G alpha(z) impacts are intact in beta-cells, and G alpha(z) activation inhibits both cAMP production and glucose-stimulated insulin secretion in the Ins-1(832/13) beta-cell-derived line. Inhibition of glucose-stimulated insulin secretion by prostaglandin E (PGE1) is pertussis-toxin insensitive, indicating that other G alpha(i) family members are not involved in this process in this beta-cell line. Indeed, overexpression of a selective deactivator of G alpha(z), the RGS domain of RGSZ1, blocks the inhibitory effect of PGE1 on glucose-stimulated insulin secretion. Finally, the inhibition of glucose-stimulated insulin secretion by PGE1 is substantially blunted by small interfering RNA-mediated knockdown of G alpha(z) expression. Taken together, these data strongly imply that the endogenous E prostanoid receptor in the Ins-1(832/13) beta-cell line couples to G(z) predominantly and perhaps even exclusively. These data provide the first evidence for G(z) signaling in pancreatic beta-cells, and identify an endogenous receptor-mediated signaling process in beta-cells that is dependent on G alpha(z) function.
First steps of tumor-related angiogenesis. (1991)

We present morphological data of the early steps of tumor-induced angiogenesis and show the distribution of the three main components of the basal lamina (BL), laminin, collagen IV, and fibronectin during these early processes. Tumor cells of a line of BSp73 AS a nonmetastasizing tumor isolated from a pancreatic adenocarcinoma were injected subcutaneously into the back of BDX rats. Two days after tumor inoculation, the BL of the dilated mother vessels around the whole circumference of the vessel has either disappeared, become fragmented, or developed several successive layers. By immunoelectron microscopy, we demonstrate that the fragmented and multilayered BL is strongly stained for laminin and collagen IV but less strongly for fibronectin. Around the surface of the dilated mother vessels which are free of any detectable BL material (by electron microscopy standards), we can see accumulation of all three components in the connective tissue. Simultaneously with the alteration of the BL, the proliferation of the endothelial cells (EC) and the pericytes and the migration of the EC from the wall of the mother vessel have started. EC migration begins in two different ways. Either one EC migrates from the wall of the mother vessel into the surrounding connective tissue, or two or more EC form nearly parallel processes toward the connective tissue. The tips of these processes are connected by intracellular junctions. Around the cellular protrusions of these cells material of the BL deposited into the nearby connective tissue can be observed neither by conventional nor by immunoelectron microscopy. During the outgrowth and migration, the EC remain in contact via junctions with the EC of the original vessel. When migration during which the EC retain their polarization continues, a slit-like lumen forms immediately between the migrating EC. This lumen always remains in direct connection with the lumen of the mother vessel. It is sealed at its border by intercellular junctions. Such junctional complexes can develop a length (in sections) of several hundred micrometers. A BL detectable in the electron microscope can neither be found around the tip of the migrating EC nor around young capillaries not yet surrounded by pericytes. By immunoelectron microscopy, however, only the cellular protrusions at the tip of migrating EC are free of deposited material of the BL. The basal surface of longer (new) capillaries is covered by a continuous layer of amorphous material.(ABSTRACT TRUNCATED AT 400 WORDS)
Design of 30 T split-pair pulse coils for LANSCE (2000)

The NHMFL has designed a high-frequency split-pair coil system for the Los Alamos Neutron Science Center (LANSCE) that can achieve fields up to 30 T for greater than 10/sup 5/ cycles and up to 26 T for 10/sup 7/ cycles in a 20 mm bore and a 5 mm clear split at the midplane. The magnet system pushes the limits of the technology by requiring a clear split, except for 14 mm of aluminum, and a 2 Hz pulse frequency. The 14 mm of aluminum is in the form of rings required to help support the 1337 kN magnetic load between the two coil halves. The clear split allows the neutrons to travel unobstructed from source to detector. The 2 Hz pulse frequency requires that the coils be continuously cooled with de-ionized water flowing at 15 m/s along the inner diameters of each coil. This paper summarizes the overall design, discusses some of the key features and predicts the coil fatigue performance based on available conductor fatigue properties. The coils are presently being fabricated and scheduled for delivery to the LANSCE in early 2000.