gebhart/patrepeval huggingface dataset:
Culture of ovine bone marrow–derived macrophages and evidence for serum factors distinct from M-CSF contributing to their propagation in vitro (1992)

An in vitro system allowing the culture of ovine bone marrow-derived macrophages (BMMs) is described. Bone marrow (BM) cells from the sternum of 4- to 9-month-old sheep were cultured in liquid suspension in hydrophobic bags with medium containing 20% autologous serum and 20% fetal calf serum (FCS). Cells with macrophage characteristics were positively selected and increased four- to five-fold between day (d) 0 and d18. Granulocytes and cells of lymphoid appearance including progenitor cells were negatively selected and were diminished 50-fold during this 18-d culture. The addition of macrophage colony-stimulating factor (M-CSF)-containing supernatants to liquid cultures did not significantly improve the yield of BMM in 18-d cultures. In contrast, cell survival at d6 and macrophage cell yield at d18 depended on the concentration and source of serum in the culture medium. FCS and 1:1 mixtures of FCS and autologous serum were superior to autologous serum alone. Analysis of growth requirements of ovine BMMs suggested that they are under more complex growth control than their murine counterparts. In an [3H]thymidine incorporation assay with BM cells collected at different times of culture, d3 or d4 BM cells responded to human recombinant M-CSF, human recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF), bovine GM-CSF, murine M-CSF or murine M-CSF-containing supernatants, and bovine interleukin 1 beta (IL-1 beta) in decreasing order of magnitude. Likewise, pure murine BMM populations harvested at d6 responded to homologous GM-CSF, IL-3, and human or murine M-CSF. FCS did not stimulate the proliferation of murine BMMs (d6) and of ovine BM cells (d3 or d4). In contrast, ovine BM cells harvested at d12 responded to FCS by proliferation in a dose-dependent manner but failed to proliferate in the presence of human or murine M-CSF or M-CSF-containing supernatants of mouse and sheep fibroblasts containing mouse macrophage growth-promoting activity. Likewise, various cytokine-containing supernatants and recombinant cytokines (murine IL-3, murine and human GM-CSF, murine and bovine IL-1 beta) did not promote proliferation of ovine d12 BM cells to an extent greater than that achieved with 15% FCS alone. Thus, ovine BMM proliferation is under the control of at least two factors acting in sequence, M-CSF and an unidentified factor contained in FCS. The ovine BMM culture system may provide a model for the analysis of myelomonocytopoiesis in vitro.
Development and evaluation of spectral classification algorithms for fluorescence guided laser angioplasty (1989)

Laser angioplasty, or the ablation of atherosclerotic plaque using laser energy, has tremendous potential to expand the scope of nonsurgical treatment of obstructive vascular disease. Clinical laser angioplasty, however, has been hindered by an unacceptable risk of vessel perforation. Laser-induced fluorescence spectroscopy can discriminate atherosclerotic from normal artery and may therefore be capable of guiding selective plaque ablation. To assess the feasibility of utilizing spectral information to discriminate arterial tissue type, several classification algorithms were developed and evaluated. Arterial fluorescence spectra from 350 to 700 nm were obtained from 100 human aortic specimens. Seven spectral classification algorithms were developed with the following techniques: multivariate linear regression, stepwise multivariate linear regression, principal components analysis, decision plane analysis, Bayes decision theory, principal peak ratio, and spectral width. The classification ability of each algorithm was evaluated by its application to the training set and to a validation set containing 82 additional spectra. All seven spectral classification algorithms prospectively classified atherosclerotic and normal aorta with an accuracy greater than 80 percent (range: 82-96 percent). Laser angioplasty systems incorporating spectral classification algorithms may therefore be capable of detection and selective ablation of atherosclerotic plaque.
Fundamentals, Applications, and Perspectives of Solid‐State Electrochemistry: A Synopsis (2009)

This chapter contains sections titled: Introduction Solid versus Liquid State Thermodynamics and Kinetics of Charge Carriers Usefulness of Electrochemical Cells Materials Research Strategies: Bulk Defect Chemistry Materials Research Strategy: Boundary Defect Chemistry Nanoionics References
[Life threatening infection with bacteroides fragilis in connection with Dalkon shield (author's transl)]. (1976)

A case of severe peritonitis in connection with the application of a Dalkon Shield is reported. By culturing the peritoneal exsudate a monoculture of Bacteroides fragilis was found as causing agens. The general aspects of severe infection in connection with IUD, particularly the Dalkon Shield, are discussed. By analysing the reports in the literature it cannot be ruled out, that Bacteroides fragilis may to be a major factor in cases with lethal outcome.
Measurement of jitter frequency variations in communication signals (2007)

Theoretical and experimental studies in this paper show that wavelet transform can clearly illustrate jitter frequency variation time trend in time/frequency domain, which gives a new analysis and visualization tool for jitter analysis. The proposed method in this paper that employs Morlet wavelet transform, combining with conventional Jitter Separation method, can measure jitter frequency variations that correlate to original signal phase and frequency variations in communication signals.
Regional vascular influences on tail-cuff measurements of drug-induced changes in systolic pressure (1975)

When drug effects are quantified using the tail-cuff method, changes in systemic arterial pressure are extrapolated from those occurring in the caudal artery. The validity of this extrapolation was tested in anesthetized rats by recording drug-induced changes in phasic arterial pressure simultaneously from catheters inserted into the lower abdominal aorta, carotid, and caudal arteries. Pressor responses to norepinephrine or angiotensin were of equal magnitude at all three sites, but phentolamine reduced systolic pressure in the aorta or caudal artery more than that in the carotid artery. Unlike previous discrepancies between carotid and tail-cuff systolic pressures, aortic hypotension caused by injections of phentolamine or pentolinium in awake normotensive or spontaneously hypertensive rats was accurately predicted by the tail-cuff method. Because drug-induced changes in diastolic pressure always varied much less than those in systolic pressure, should indirect measurement of diastolic pressure become technically feasible, it might be preferable for assessing drug effects on blood pressure.
Querying Community Web Portals (2000)

A new generation of information systems such as organizational memories, vertical aggregators, infomediaries, etc. is emerging nowadays. Such systems, termed Community Web Portals, intend to support specific communities of interest (e.g., enterprise, professional, trading) on corporate intranets or the Web. More precisely, Portal Catalogs, organize and describe various information resources (e.g., sites, documents, data) for diverse target audiences (corporate, inter-enterprise, e-marketplace, etc.), in a multitude of ways, which are far more flexible and complex than those provided by standard (relational or object) databases. Yet, in commercial software for deploying Community Portals, querying is still limited to full-text (or attribute-value) retrieval and more advanced information-seeking needs implies navigational access. Furthermore, recent Web standards for describing resources are completely ignored. In this
Bayesian-Inference-Based Recommendation in Online Social Networks (2012)

In this paper, we propose a Bayesian-inference-based recommendation system for online social networks. In our system, users share their content ratings with friends. The rating similarity between a pair of friends is measured by a set of conditional probabilities derived from their mutual rating history. A user propagates a content rating query along the social network to his direct and indirect friends. Based on the query responses, a Bayesian network is constructed to infer the rating of the querying user. We develop distributed protocols that can be easily implemented in online social networks. We further propose to use Prior distribution to cope with cold start and rating sparseness. The proposed algorithm is evaluated using two different online rating data sets of real users. We show that the proposed Bayesian-inference-based recommendation is better than the existing trust-based recommendations and is comparable to Collaborative Filtering (CF) recommendation. It allows the flexible tradeoffs between recommendation quality and recommendation quantity. We further show that informative Prior distribution is indeed helpful to overcome cold start and rating sparseness.
Phylogenetic analysis of sequences from diverse bacteria with homology to the Escherichia coli rho gene (1994)

Genes from Pseudomonas fluorescens, Chromatium vinosum, Micrococcus luteus, Deinococcus radiodurans, and Thermotoga maritima with homology to the Escherichia coli rho gene were cloned and sequenced, and their sequences were compared with other available sequences. The species for all of the compared sequences are members of five bacterial phyla, including Thermotogales, the most deeply diverged phylum. This suggests that a rho-like gene is ubiquitous in the Bacteria and was present in their common ancestor. The comparative analysis revealed that the Rho homologs are highly conserved, exhibiting a minimum identity of 50% of their amino acid residues in pairwise comparisons. The ATP-binding domain had a particularly high degree of conservation, consisting of some blocks with sequences of residues that are very similar to segments of the alpha and beta subunits of F1-ATPase and of other blocks with sequences that are unique to Rho. The RNA-binding domain is more diverged than the ATP-binding domain. However, one of its most highly conserved segments includes a RNP1-like sequence, which is known to be involved in RNA binding. Overall, the degree of similarity is lowest in the first 50 residues (the first half of the RNA-binding domain), in the putative connector region between the RNA-binding and the ATP-binding domains, and in the last 50 residues of the polypeptide. Since functionally defective mutants for E. coli Rho exist in all three of these segments, they represent important parts of Rho that have undergone adaptive evolution.
Krupp Thyssen Nirosta公司生产的不锈钢 (2000)

在Bochum钢厂，AOD炼钢是瓶颈障碍，而在Krefeld钢厂瓶颈障碍则是UHP炉。AOD转炉采用不同的工艺技术对策，可以使两钢厂的全部生产设备发挥最佳的生产能力。而且在Bochum钢厂采用对二次冶金处理设施进行控制，并在组织与空间上进行合并。这样进行运转，生产能力得到提高，并获得较好的冶金指标。
The Maillard Reaction in Food Products Carbon Dioxide Production (1967)

SUMMARY— The nonenzymic production of gas in food products stored under tropical conditions can, in many cases, be attributed to the reaction between free amino acids and reducing sugars. Carbon dioxide production in model systems has been studied and its relationship to brown pigment and conjugated unsaturated carbonyl compounds investigated. Over a wide range of pH the variations of sugar, amino acid and temperatures used showed that the type of sugar was the limiting factor in rate of carbon dioxide production rather than the amino acid. Rate increased from disaccharide to hexose to pentose and with rise in pH and temperature. However relative reactivity is a temperature dependent function for lactose and glucose because of the different activation energy involved. Carbon dioxide was formed mainly via the Strecker degradation but it has been demonstrated that another unidentified pathway is available for the formation of carbon dioxide from sugars in the presence of amino compounds. Evidence for the similarities in reaction pathways for the formation of the three end products—carbon dioxide, brown pigment and conjugated unsaturated carbonyl compounds‐is presented. The possibility of using the determination of carbonyl compounds as a sensitive indicator of future spoilage due to gas formation is suggested.
Joint Sparsity with Mixed Granularity for Efficient GPU Implementation (2021)

Given the over-parameterization property in recent deep neural networks, sparsification is widely used to compress networks and save memory footprint. Unstructured sparsity, i.e., fine-grained pruning, can help preserve model accuracy, while structured sparsity, i.e., coarse-grained pruning, is preferred for general-purpose hardwares, e.g., GPUs. This paper proposes a novel joint sparsity pattern using mixed granularity to take advantage of both unstructured and structured sparsity. We utilize a heuristic strategy to infer the joint sparsity pattern by mixing vector-wise fine-grained and block-wise coarse-grained pruning masks. Experimental results show that the joint sparsity can achieve higher model accuracy and sparsity ratio while consistently maintaining moderate inference speed for VGG-16 on CIFAR-100 in comparison to the commonly used block sparsity and balanced sparsity strategies.
The LIA-EURECOM RT`09 Speaker Diarization System (2009)

This paper presents LIA-EURECOM’s joint submission to the NIST Rich Transcription 2009 (RT‘09) speaker diarization evaluation. We describe a number of modifications to our previous system which involve beamforming for the multiple distant microphone (MDM) condition and also significant enhancements to the speaker segmentation stage of the core speaker diarization system. These modifications lead to improvements in both speech activity detection (MDM only) and also to overall diarization performance. We present experimental results on a development set of 23 shows and the RT‘07 dataset, which was used for validation. Experimental results on the latter show a relative improvement in DER of 27% is achieved with our new system on the MDM condition. Similar experiments on the RT‘09 dataset show a relative improvement in DER of 35%. Our results for the MDM condition compare reasonably well with those of others even if, other than for beamforming, we did not use any delay features. Results for the single distant microphone condition (SDM) compare especially well with others’ work and highlight the merit of our top-down, evolutive hidden Markov model (E-HMM) approach to speaker diarization.
The Feeding Ecology of Flatfish in the Northwest Atlantic (2002)

Flatfish are an economically and ecologically important component of continental shelf ecosystems worldwide. These species are impacted from fishing activities, both as direct targets and through indirect effects on habitat and food supply. We examined 25 years of diet data for juveniles and adults of nine species of flatfish in the Northwest Atlantic on the continental shelf off of the USA and parts of Canada in order to understand how flatfish feeding ecology may have changed after decades of fishing and related impacts on the ocean bottom. Atlantic halibut (Hippoglossus hippoglossus), summer flounder (Paralichthys dentatus) and fourspot flounder (P. oblongus) were generally piscivorous. American plaice (Hippoglossoides platessoides) ate primarily ophiuroids. Yellowtail flounder (Limanda ferruginea), winter flounder (Pseudopleuronectes americanus), windowpane (Scophthalmus aquosus), witch flounder (Glyptocephalus cynoglossus) and gulfstream flounder (Citharichthys arctifrons) ate primarily polychaetes, gammarids and other benthic invertebrates. American plaice, summer flounder and fourspot flounder exhibited significant ontogenetic shifts in diet, consuming fewer polychaetes with increasing size. Summer and fourspot flounder also exhibited significant shifts in diet across the time series. None of the benthivorous flatfish exhibited significant changes in diet composition across the time series. The mean weight of stomach contents declined in all species over the past 20 years. The role of flatfish trophic dynamics is discussed in the context of major changes that have occurred in this continental shelf ecosystem.
Molecular cloning and characterization of cDNA for human myeloperoxidase. (1987)

Partial amino acid sequence of human myeloperoxidase was determined, and a 41-base oligonucleotide containing deoxyinosines at four positions was chemically synthesized. By using the oligonucleotide as a probe, cDNA clones for human myeloperoxidase were isolated from a cDNA library constructed with mRNA from human promyelocytic leukemia HL-60 cells. One of the clones containing a 2.6-kilobase insert was subjected to nucleotide sequence analysis. The sequence was found to contain an open reading frame, 2,235 nucleotides coding for a protein of 745 amino acids with a calculated Mr of 83,868. The heavy chain of myeloperoxidase, consisting of 467 amino acids, was located on the COOH terminus half of the protein. The RNA specified by the cDNA was prepared using SP6 RNA polymerase and translated in rabbit reticulocyte lysates, and the product was identified as human myeloperoxidase by immunoprecipitation with rabbit anti-human myeloperoxidase antibody. By Northern hybridization analysis of RNA from leukemic cells, it was shown that myeloperoxidase mRNA is abundantly expressed in human promyelocytic HL-60 and mouse myeloid leukemia NFS-60 cells. Furthermore, the results of Southern hybridization analysis of human genomic DNA suggest that there are one or two genes for myeloperoxidase in the human haploid genome.
Incidence of anti Hsp 90 and 70 antibodies in children with SLE, juvenile dermatomyositis and juvenile chronic arthritis. (1996)

The incidence of antibodies to hsp90 in childhood-onset SLE resembles that described in adult onset disease suggesting that, despite clinical differences between the two, a subset of each may share a similar pathological mechanism of disease.
Design of Experiments: Useful Orthogonal Arrays for Number of Experiments from 4 to 16 (2007)

A methodology for the design of an experiment is proposed in order to find asmany schemes as possible with the maximum number of factors with different levels for thesmallest number of experimental runs. An algorithm was developed and homemadesoftware was implemented. The abilities in generation of the largest groups of orthogonalarrays were analyzed for experimental runs of 4, 6, 8, 9, 10, 12, 14, 15, and 16. The resultsshow that the proposed method permits the construction of the largest groups of orthogonalarrays with the maximum number of factors.
ChemInform Abstract: SYNTHESIS AND REACTIONS OF OXAZIRIDINES. ADAMANTANE‐2‐SPIRO‐3′‐OXAZIRIDINE AND ITS N‐ALKYL DERIVATIVES (1985)

Abstract Die durch Kondensation von Adamantan‐2‐on (I) mit den Aminen (II) nach den Methoden A),B) oder C) erhaltenen Schiffschen Basen (III) werden durch Oxidation nach den Verfahren D) bzw. E) in die Oxaziridine (IV) übergeführt.
The role of hematopoietic stem cell transplantation for type 1 diabetes mellitus (2008)

In this review, we present 1) scientific basis for the use of high dose immunosuppression followed by autologous peripheral blood hematopoietic stem cell transplantation for newly diagnosed type 1 diabetes mellitus, 2) an update of clinical and laboratory outcomes in 21 patients transplanted at the University Hospital of the Ribeirão Preto Medical School, University of São Paulo, Brazil, including 6 relapses in patients without previous ketoacidosis and 3) a discussion of future prospectives of cellular therapy for type 1 diabetes mellitus.
Low-level HIV-1 replication and the dynamics of the resting CD4+T cell reservoir for HIV-1 in the setting of HAART (2008)

The intrinsic stability of the latent reservoir has important implications for efforts to eradicate HIV-1 infection and suggests that intensified HAART would not accelerate the decay of the latent reservoir.
Inhibitory Effect of Some Oxygenated Stigmastane-Type Sterols on 12-O-Tetradecanoylphorbol-13-acetate-Induced Inflammation in Mice. (1995)

The oxygenated stigmastane-type sterols stigmastane-3 beta, 6 alpha-diol, stigmastane-3 beta, 6 beta-diol, 7 alpha-hydroxysitosterol and its diacetyl derivative, 7 beta-hydroxysitosterol and its diacetyl derivative, 7-oxositosterol, 4 beta-hydroxysitosterol, and stigmast-4-ene-3 beta, 6 beta-diol were evaluated with respect to their anti-inflammatory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. All of the sterols, with the exception of 7 alpha-hydroxysitosterol and its diacetyl derivative, were found to possess marked inhibitory activity. The 50% inhibitory dose of these compounds for TPA-inflammation (1 microgram) was 0.5--1.0 mg/ear.
OVOPS, Object Virtual Operations System for Distributed Applications Development (1994)

Nitrogen-Vacancy (NV) centers in diamond are promising solid-state quantum emitters that can be utilized for photonic quantum applications. Various diamond nanophotonic devices have been fabricated for efficient extraction of single photons emitted from NV centers to a single guided mode. However, for constructing scalable quantum networks, further efficient coupling of single photons to a guided mode of a single-mode fiber (SMF) is indispensable and a difficult challenge. Here, we propose a novel efficient hybrid system between an optical nanofiber and a cylindrical-structured diamond nanowire. The maximum coupling efficiency as high as 75% for the sum of both fiber ends is obtained by numerical simulations. The proposed hybrid system will provide a simple and efficient interface between solid-state quantum emitters and a SMF suitable for constructing scalable quantum networks.
Super-resolution MRI images using Compressive Sensing (2012)

Compressive Sensing (CS) is a new method for sparse images reconstruction using incomplete measurements. In this study our goal is to reconstruct a High Resolution (HR), MR image from a single Low Resolution (LR) image. Our proposed method applies the CS theory to Super Resolution (SR) single Magnetic Resonance Imaging (MRI). We first use a LR image generated by applying a Gaussian filter on the original image (for k-space under-sampling) and then generate the HR image by using CS theory. The formulation of CS theory emphasizes on maximizing image sparsity on known sparse transform domain and minimizing fidelity. For satisfying sparsity, finite difference is applied as a sparsifying transform. We propose and compare the Non-Linear Conjugate Gradients (NLCG) and Split Bregman (SB) algorithms as two different image reconstructing methods in CS. The result images are compared with three types of images: Original image which is used as the input of experiments, low quality of original image and the image which is generated by Zero Filling (ZF) algorithm. The following measures are used for evaluation: SNR, PSNR, SSIM and MSE. Experiments show that the SB algorithm outperforms ZF and NLCG for reconstructing MR images.