gebhart/patrepeval huggingface dataset:
Interpretation of very thin gas sands in Italy (1984)

In North Eastern Italy large production of gas is obtained from very thin sands inter-laminated with shales. Normal interpretation methods fail because the sand thickness may be as low as one or two inches and invasion is often rather deep. A satisfactory interpretation method must provide: detection of each individual sand, qualitative gas indication, and a running average evaluation of porosity. In order to provide the necessary information the logs should be recorded at 1.2'' sampling rate and have high vertical resolution: thus the Electromagnetic Propagation log and a Micro-Resistivity should be included. As an absolute minimum, the Dipmeter curves can be used to define individual beds. A simple method, based on cut-offs on the Electromagnetic Attenuation or Resistivity curve, can be used to distinguish the sands; however a much better detection is obtained from a pattern recognition method using the shape of the above curves rather than their absolute value. This can normally recognize individual sands down to less than 2'' thickness.
Development of soccer agents with object migration (2003)

This paper describes our experience in developing soccer agents, Kasuga-bito II, with object migration. We developed soccer agents with object migration using object serialization and the class loader in Java. However, we have found from our experience in the development of these agents that these two techniques in Java are not so powerful. Our experience gained is described.
Gene transfer into the mammalian kidney: microtransplantation of retrovirus-transduced metanephric tissue. (1994)

Our previous observation that embryonic kidney tissue can develop and differentiate when transplanted into the parenchyma of mouse kidneys in the postnatal period provided an avenue for transferring novel genes into the mammalian kidney in vivo. Mouse metanephric tissue was infected ex vivo with a replication defective retrovirus which transduces the gene for beta-galactosidase. Seven to 21 days after transplantation of this tissue into neonatal and adult mouse kidneys, the expression of the gene, controlled by the viral long-terminal repeat promoter, was noted in approximately one-third of implants. Gene expression occurred predominantly in glomerular epithelial cells, but also in interstitial cells and in vascular structures. Polymerase chain reaction amplification of renal genomic DNA indicated the presence of viral DNA in 9 of 10 kidneys which had received metanephric implants into the neonatal renal cortex. These studies demonstrate the feasibility of short-term gene transfer into and expression within the mammalian kidney.
Foresight in Laryngology and Laryngeal Surgery: A 2020 Vision (2007)

Laryngology and laryngeal surgery have been in the vanguard of minimally invasive human procedural interventions for approximately 150 years. The natural passages through the oral cavity, nose, and pharynx have provided an accessible gateway to the larynx that has allowed for rapid translation of a variety of diagnostic and therapeutic technologies. Transoral and transcervical laryngeal surgery have been further facilitated by progressive advancements in local, topical, intravenous, and general anesthesia. With rapid developments in engineering disciplines (ie, tissue, chemical, mechanical) and voice science, there are a variety of current and near-term opportunities to advance our field. This report represents a panel at the 2005 American Broncho-Esophagological Association meeting that sought to use present perspectives, combined with cutting-edge research insights, to provide foresight into key aspects of laryngology that we believe will be developed by the year 2020. We hope that aspiring laryngeal surgeons will find elements of this discussion valuable for devising a strategic roadmap for research initiatives in laryngology and laryngeal surgery.
<i>Model Organisms: New Insights Into Ion Channel and Transporter Function</i>. Stomatin homologues interact in<i>Caenorhabditis elegans</i> (2001)

In C. elegans the protein UNC-1 is a major determinant of anesthetic sensitivity and is a close homologue of the mammalian protein stomatin. In humans stomatin is missing from erythrocyte membranes in the hemolytic disease overhydrated hereditary stomatocytosis, despite an apparently normal stomatin gene. Overhydrated hereditary stomatocytosis is characterized by alteration of the normal transmembrane gradients of sodium and potassium. Stomatin has been shown to interact genetically with sodium channels. It is also postulated that stomatin is important in the organization of lipid rafts. We demonstrate here that antibodies against UNC-1 stain the major nerve tracts of Caenorhabditis elegans, with very intense staining of the nerve ring. We also found that a gene encoding a stomatin-like protein, UNC-24, affects anesthetic sensitivity and is genetically epistatic to unc-1. In the absence of UNC-24, the staining of the nerve ring by anti-UNC-1 is abolished, despite normal transcriptional levels of the unc-1 mRNA. Western blots indicate that UNC-24 probably affects the stability of the UNC-1 protein. UNC-24 may therefore be necessary for the correct placement of UNC-1 in the cell membrane and organization of lipid rafts.
Comparative Evaluation of Three Different Genotyping Methods for Investigation of Nosocomial Outbreaks of Legionnaires' Disease in Hospitals (2000)

The increased incidence of nosocomial Legionnaires' disease in two hospitals prompted investigation of possible environmental sources. In the search for an effective DNA-typing technique for use in hospital epidemiology, the performance and convenience of three methods-SfiI macrorestriction analysis (MRA), amplified fragment length polymorphism (AFLP), and arbitrarily primed PCR (AP-PCR)-were compared. Twenty-nine outbreak-associated and eight nonassociated strains of Legionella pneumophila with 13 MRA types and subtypes were investigated. These strains comprised isolates from bronchoalveolar lavages, from environmental, patient-related sources, and type strains. All three typing methods detected one predominant genotype associated with the outbreaks in both hospitals. All of them correctly assigned epidemiologically associated, environmental isolates to their respective patient specimens. AP-PCR was the least discriminating and least reproducible technique. In contrast, AFLP was demonstrated as being the method with the best interassay reproducibility (90%) and concordance (94%) in comparison to the genotyping standard of MRA and the epidemiological data. Analysis of AFLP fragments revealed 12 different types and subtypes. Because of its simplicity and reproducibility, AFLP proved to be the most effective technique in outbreak investigation.
Isolation of oxytocic peptides from Oldenlandia affinis by solvent extraction of tetraphenylborate complexes and chromatography on sephadex LH-20. (1973)

To extract the water-soluble oxytocic polypeptides in Oldenlandia af finis DC, a plant used in African folk medicine as an oral oxytocic, dried above-ground parts were soaked in boiling water for 30 minutes, filtered, and the filtrate shaken for 15 minutes with a .1 M solution of sodium tetraphenylborate (NaTPB) in n-butanol. The butanol layer was separated and shaken with hydrochloric acid for 3 minutes to convert the TPB complexes to hydrochlorides, then washed with water until the pH reached 3, and dried. Ether was added to the dried butanol fraction, fo rming a fluffy yellow precipitate, treated again, forming an almost white precipitate, then examined by chromatography. During the n-butanol and ether treatment some serotonin known to be present in the plant was coprecipitated; in reprecipitation this remained in solution. 2 polypeptides were found. Both came from the same fraction, gave the same ultraviolet spectrum, the same color reaction, and had the same biological effect. After separation with Tlc only the compound with the highest RF value was isolated in sufficient quantities for degration. The amino acid composition has been determined and further structural studies are in progress.
A study for control of a power assist device (2005)

A power assisting device for lower back flexion and extension, when carrying a heavy load is presented in this paper. When people lift up something heavy, they use both hands. So the development of a controller without using hands is necessary. We attempt to control the device by a voluntary human motion. First, lifting up and putting down motions are analyzed using a human model. Results show that torques in a hip joint and a knee joint are characteristic for control the device. It means that EMG signals in front and back thigh muscles can become feature values because the muscles located there connect the hip joint and the knee joint. After that, a controller of the device using the EMG signals is developed. Finally, artificial neural networks (ANN) are introduced as a solution of the problem of individual differences.
Leukotriene-Receptor Antagonists and 5-Lipoxygenase Inhibitors in Asthma (1993)

Advancements in the pathogenesis of asthma are beginning to define a role for the leukotrienes. Although more studies are needed to assess the efficacy of leukotriene inhibitors, recent clinical trials using leukotriene-receptor antagonists and 5-lipoxygenase inhibitors indicate a potential for the expansion of therapeutic regimens currently used in the treatment of asthma.
Use of a Mineral Fines Stabilizer in Well Completions (1984)

Abstract Formation damage in the vicinity of the wellbore is a major cause of low productivity1–6 and the difficulties attendant to restoration of the damage leave a significant number of wells that do not respond to remedial treatment.1 Operators have recognized the importance of damage control during drilling, workover and other operations and have used filtration processes to reduce the damage caused by fluids invading the formation. Until recently, however, little could be done to control permeability damage caused by the movement of fine particles native to the formation of interest. Prevention of the migration of fine particles (defined) as those having a diameter less than 44 micrometers and which will pass through the openings of a 325 U.S. mesh screen7) is a complex problem. Certain cationic organic polymers (COP's) have been developed to control the swelling of water-expandable clays such smectite in the presence of low salinity fluids.8–14 While damaging in itself, the major detrimental aspect of smectite swelling is the associated release of fine particles.8 This arises because, when present, the particles. This arises because, when present, the smectite clay frequently acts as the cementation medium holding sand grains and fine particles in place.7,8
The Transmission of Hydrogen through Metals (1951)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation H. B. Wahlin; The Transmission of Hydrogen through Metals. J. Appl. Phys. 1 December 1951; 22 (12): 1503. https://doi.org/10.1063/1.1699903 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioJournal of Applied Physics Search Advanced Search |Citation Search
The Operational Global Icosahedral–Hexagonal Gridpoint Model GME: Description and High-Resolution Tests (2002)

The German Weather Service (Deutscher Wetterdienst) has recently developed a new operational global numerical weather prediction model, named GME, based on an almost uniform icosahedral-hexagonal grid. The GME gridpoint approach avoids the disadvantages of spectral techniques as well as the pole problem in latitudelongitude grids and provides a data structure extremely well suited to high efficiency on distributed memory parallel computers. The formulation of the discrete operators for this grid is described and evaluations that demonstrate their second-order accuracy are provided. These operators are derived for local basis functions that are orthogonal and conform perfectly to the spherical surface. The local basis functions, unique for each grid point, are the latitude and longitude of a spherical coordinate system whose equator and zero meridian intersect at the grid point. The prognostic equations for horizontal velocities, temperature, and surface pressure are solved using a semi-implicit Eulerian approach and for two moisture fields using a semi-Lagrangian scheme to ensure monotonicity and positivity. In the vertical direction, finite differences are applied in a hybrid (sigma pressure) coordinate system to all prognostic variables. The semi-implicit treatment of gravity waves presented here leads to a 3D Helmholtz equation that is diagonalized into a set of 2D Helmholtz equations that are solved by successive relaxation. Most of the same physical parameterizations used in the authors' previous operational regional model, named EM, are employed in GME. Some results from the verification process for GME are provided and GME performance statistics on a Cray T3E1200 as well as on the ECMWF Fujitsu VPP5000 systems are summarized. For the case of the severe Christmas 1999 storm over France and Germany the pronounced sensitivity of the model with respect to the initial state is discussed. Finally, a test case is shown where it is currently possible, though not yet operationally practical, to run GME at 15-km resolution on the VPP5000.
Natural Variation in Neuron Number in Mice Is Linked to a Major Quantitative Trait Locus on Chr 11 (1998)

Common genetic polymorphisms-as opposed to rare mutations-generate almost all heritable differences in the size and structure of the CNS. Surprisingly, these normal variants have not previously been mapped or cloned in any vertebrate species. In a recent paper (), we suggested that much of the variation in retinal ganglion cell number in mice, and the striking bimodality of strain averages, are caused by one or two quantitative trait loci (QTLs). To test this idea, and to map genes linked to this variable and highly heritable quantitative trait, we have counted ganglion cells in 38 recombinant inbred strains (BXD and BXH) derived from parental strains that have high and low cell numbers. A genome-wide search using simple and composite interval-mapping techniques revealed a major QTL on chromosome (Chr) 11 in a 3 cM interval between Hoxb and Krt1 (LOD = 6.8; genome-wide p = 0.001) and possible subsidiary QTLs on Chr 2 and Chr 8. The Chr 11 locus, neuron number control 1 (Nnc1), accounts for one third of the genetic variance among BXH strains and more than half of that among BXD strains, but Nnc1 has no known effects on brain weight, eye weight, or total retinal cell number. Three strong candidate genes have been mapped previously to the same region as Nnc1. These genes-Rara, Thra, and Erbb2- encode receptors for retinoic acid, thyroxine, and neuregulin, respectively. Each receptor is expressed in the retina during development, and their ligands affect the proliferation or survival of retinal cells.
Warm mix asphalt (WMA) review (2007)

This report reviewed various approaches to produce warm mix asphalt (WMA) and their laboratory and field assessments. Reviewed technologies are the foamed mix based products (Aspha-Min, WAM-Foam and LEA), organic additive products (Sasobit, Asphaltan B, CECABASE RT 92 and Licoment BS100) and finally emulsion based products (Evotherm and WAM-Emulsion). The WMA products appeared to have many potential benefits. Although using WMA is likely to have higher initial construction cost at present, it appears to be a useful technology for the industry and worth further investigation. The lower production temperatures used in WMA processes may lead to increased moisture sensitivity issues for the mixes. Although many laboratory/field trials using some of the WMA products typically demonstrated positive outcomes, long term performance monitoring (along with better understanding on environmental and economic impacts) is essential to evaluate the true benefits/risks of the WMA products. (a)
Regioselective Patterning of Multiple SAMs and Applications in Surface-Guided Smart Microfluidics (2014)

A top-down nanofabrication technology is developed to integrate multiple SAMs (self-assembled monolayers) into regioselective patterns. With ultraviolet light exposure through regioselectively hollowed hard mask, an existing SAM at designated microregions can be removed and a dissimilar kind of SAM can be regrown there. By repeating the photolithography-like process cycle, diverse kinds of SAM building blocks can be laid out as a desired pattern in one microfluidic channel. In order to ensure high quality of the surface modifications, the SAMs are vapor-phase deposited before the channel is closed by a bonding process. For the first time the technique makes it possible to integrate three or more kinds of SAMs in one microchannel. The technique is very useful for multiplex surface functionalization of microfluidic chips where different segments of a microfluidic channel need to be individually modified with different SAMs or into arrayed pattern for surface-guided fluidic properties like hydrophobicity/philicity and/or oleophobicity/philicity, etc. The technique has been well validated by experimental demonstration of various surface-directed flow-guiding functions. By modifying a microchannel surface into an arrayed pattern of multi-SAM "two-tone" stripe array, surface-guiding-induced 3D swirling flow is generated in a microfluidic channel that experimentally exhibits quick oil/water mixing and high-efficiency oil-to-water chemical extraction.
Tau Protein in Cerebrospinal Fluid (1998)

Tau is the main protein of paired helical filaments. It can be detected and measured in cerebrospinal fluid (CSF) and for this reason it has been proposed as a possible in vivo marker of Alzheimer disease (AD). To evaluate the usefulness of CSF tau in the diagnosis of AD we measured it in patients with AD, frontal lobe dementia (FLD), vascular dementia (VD), and in healthy controls by means of a specific enzyme-linked immunosorbent assay test. Individuals with AD had significantly higher tau levels than FLD, VD, and controls. Individuals with late onset AD had significantly higher levels than those with early onset disease. In AD, CSF tau level did not correlate with age, duration, or severity of the disease, whereas a correlation with age was found in FLD and controls. In the nine AD patients in whom CSF tau measurement was repeated after 2 years, mean levels did not differ from baseline, although a worsening of cognitive performances occurred. The overlap among the different groups and the absence of any modification over time suggest that CSF tau measurement, more than in confirming or staging overt AD, might be useful in revealing the disease at its preclinical phase.
Model for the Solid-Liquid Phase Transitions (Melting) of Undiluted Random Semicrystalline Copolymers of Vinylidene Chloride with Methyl Acrylate Monomers (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModel for the Solid-Liquid Phase Transitions (Melting) of Undiluted Random Semicrystalline Copolymers of Vinylidene Chloride with Methyl Acrylate MonomersBernard E. Obi, Phillip DeLassus, and Eric A. GrulkeCite this: Macromolecules 1994, 27, 19, 5491–5497Publication Date (Print):September 1, 1994Publication History Published online1 May 2002Published inissue 1 September 1994https://pubs.acs.org/doi/10.1021/ma00097a032https://doi.org/10.1021/ma00097a032research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Influence of controlled dietary restriction on immunologic function and aging. (1979)

The underfeeding regimens tested in rodents for life span prolongation and/or immunologic effects result in a complex blend of protein and energy restriction while offering at least adequate amounts of all other essential nutrients. Underfeeding started at weaning and continued throughout life represents the only proved way of slowing the rate of aging in homeotherms. Mounting evidence indicates that underfeeding initiated later in life may also influence life span favorably. Old mice after lifelong restriction, or moderately aged mice (16.5 months) after 4.5 months of restriction, display "younger" immune systems than do age-matched, normally fed controls, as judged by response to mitogens, the mixed lymphocyte reaction, and other determinants. The immunologic effects of underfeeding, when measured quite early in life, are strain-dependent in the mouse. Diets designed to restrict the intake per week of energy (but not protein) produce the same effects on immune response capacity in very young mice as do energy restricted, protein unbalanced regimens. Underfeeding early in life drastically dampens thymic growth and alters the timing of involution. Early restriction also produces a profound lowering of body temperature in young (C57BL/10Sn x C3H/HeDiSn)F1 females. On the other hand, temperature lowering was not observed in males of this hybrid fed normally for the first year of life and restricted for 3 months prior to measurement. The mechanisms behind these various effects of controlled dietary restriction (i.e., undernutrition without malnutrition) are poorly understood at present.
In vitro and in vivo Evaluation of the Antitumor Efficiency of Resveratrol Against Lung Cancer (2013)

Lung cancer remains a deadly disease with unsatisfactory overall survival. Resveratrol (Res) has the potential to inhibit growth of several types of cancer such as prostate and colorectal examples. In the current study, we evaluated in vitro and in vivo anticancer efficiency of Res in a xenograft model with A549 cells. Cell inhibition effects of Res were measured by MTT assay. Apoptotis of A549 cells was assessed with reference to caspase-3 activity and growth curves of tumor volume and bodyweight of the mice were measured every two days. In vitro cytotoxicity evaluation indicated Res to exert dose-dependent cell inhibition effects against A549 cells with activation of caspase-3. In vivo evaluation showed Res to effectively inhibit the growth of lung cancer in a dose- dependent manner in nude mice. Therefore, we believe that Res might be a promising phytomedicine for cancer therapy and further efforts are needed to explore this potential therapeutic strategy.