gebhart/patrepeval huggingface dataset:
Enhancement of seismic data gathered by floating ice acquisition: Application of local kinematic attributes (2016)

The presence of large areas covered by shallow waters, like swamps, rivers, lakes and so on, troubles seismic exploration in the Russian Far North in summer. The winter seems to be much more appropriate time to implement seismic acquisitions for reasonable cost but with acceptable quality of the data. The same is true for transition zones. Really, in winter there is possible, at least technically, use floating ice and apply the developed technology for onshore seismic study. But in winter there is another complicating factor - intensive seismic noise generated by sources placed onto ice covering shallow waters. It is well known that this noise is connected with flexural waves propagating along the ice. These waves are much slower than surface waves, which are well studied for onshore acquisitions and, hence, seem to be easy avoided by the modern versions of f-k filters. Unfortunately, straightforward application of this type of noise suppression fails. To understand the matter, the representative series of numerical experiments are conducted which prove that the main impact to noise is multiple conversions of flexural waves to the body ones and vice versa. Ways to reduce this noise by special processing procedures are proposed and discussed. Presentation Date: Tuesday, October 18, 2016 Start Time: 8:25:00 AM Location: 140 Presentation Type: ORAL
Fasting blood sugar level: a determinant for in-hospital outcome in patients with first myocardial infarction and without glucose intolerance. (1993)

The body responds to stress, e.g. during infections or acute illnesses, by a variety of neurohormonal mechanisms. Some of these physiological responses sometimes lead to an elevation of the blood sugar level (BSL). BSL is a biochemical parameter which is readily and rapidly assayed. The aim of our study was to determine whether the glycaemic state of patients with their first myocardial infarction and without previous glucose intolerance was of predictive value for the type of outcome during the in-hospital and post-hospitalisation periods. We also delineated the factors which determined subsequent glucose tolerance in this group of patients. Forty-four consecutive patients were studied and those with complicated in-hospital outcome had a significantly higher mean BSL at admission (ABSL) and fasting BSL (FBSL). FBSL was shown to be a predictor for in-hospital outcome. The odds ratio for a complicated in-hospital outcome was 3.3 times for patients with a FBSL of greater than 6.7 mmol/l (120 mg/dl) than those without (p = 0.0175). We could not identify a predictor for an adverse outcome in the post-hospitalisation period. Oral glucose tolerance test was performed on twenty-seven patients at least six weeks after the infarction. Twelve were normal and fifteen were abnormal (six were diabetic and nine had impaired glucose tolerance). The odds ratio for patients with glycosylated haemoglobin level (HbAlc) between 7.5 and 9.5% was 2.19 higher than those less than 7.5% (p = 0.049). In conclusion, the FBSL is a determinant for the outcome for these patients during the in-hospital and not the post-hospitalisation period.(ABSTRACT TRUNCATED AT 250 WORDS)
Cernent Resistivity and Implications for Measurement of Formation Resistivity Through Casing (1993)

ABSTRACT Measurement of formation resistivity through casing is an emerging logging technology, with prototype logging tools currently under development. Modeling studies show that the presence of cement could reduce the sensitivity of the TCRT™ (Through Casing Resistivity Tool™). Physically this tool has some similarity to a laterolog. Measurements would be seriously affected if the cement was much more resistive than the formation. We have carried out a laboratory study of cement resistivity with the funding from the Gas Research Institute. Our main objective was to provide hard data to use in assessing the impact of cement resistivity on measurements made with the TCRT™. Our results show that cement resistivity is generally low, varying from less than 1 to 8 Ω-m at 120° F. Light-weight cements were generally the least resistive, with Class A, G and H cements more resistive. Resistivity was essentially independent of either confining or pore pressure. It was also independent of either current density or voltage. Cement resistivity appears to vary with temperature according to Arp's equation, as would be expected for nonconductive material saturated with water. Thin sections and mercury injection capillary pressure data show that porosity in cement is dominantly microporosity, with pore throat diameter less than 0.1 microns. In addition helium porosity is high, ranging from 35 to 40%. The low observed resistivity is due to large amounts of water-filled microporosity. The results of this study signify that the presence of cement will not seriously degrade measurements of resistivity through casing in many environments. Our work concentrated on cements normally used on the North Slope of Alaska, as well as Class H cement, a common Gulf Coast cement. Potential applications of the TCRT™ include water flood monitoring at Prudhoe Bay and elsewhere, and detection of "missed pay" behind casing.
Unilateral External Fixation for Severe Pilon Fractures (1993)

Twenty-one patients with severe tibial plafond fractures were treated by unilateral large screw external fixation. In 15 patients, this was combined with limited internal fixation. The fractures were classified according to the methods of Ovadia and Beals. There were nine type III, four type IV, and eight type V fractures, and according to the methods of Rüedi and Allgöwer, nine type II and 12 type III fractures. Seven fractures were open. In five fractures, no attempt was made at articular reconstruction due to severe comminution. Four of these fractures required ankle arthrodeses and one type IIIB fracture received a late amputation. All other fractures healed. There were no cases of wound infection, skin slough, or osteomyelitis. Large screw external fixation in the talus and calcaneus was not associated with significant early or late complications. The less extensive tissue dissection in an area prone to wound complications may account for the low rates of infections, wound complications, and nonunion.
Percy Grainger in His Letters (1988)

A discussion of a collection of letters by the concert pianist Percy Grainger, published in 'The Farthest North of Humanness' (edited by Kay Dreyfus).
Structural similarities in glutaminyl- and methionyl-tRNA synthetases suggest a common overall orientation of tRNA binding. (1991)

Detailed comparisons between the structures of the tRNA-bound Escherichia coli glutaminyl-tRNA (Gln-tRNA) synthetase [L-glutamine:tRNA(Gln) ligase (AMP-forming), EC 6.1.1.18] and recently refined E. coli methionyl-tRNA (Met-tRNA) synthetase [L-methionine:tRNA(Met) ligase (AMP-forming), EC 6.1.1.10] reveal significant similarities beyond the anticipated correspondence of their respective dinucleotide-fold domains. One similarity comprises a 23-amino acid alpha-helix-turn-beta-strand motif found in each enzyme within a domain that is inserted between the two halves of the dinucleotide binding fold. A second correspondence, which consists of two alpha-helices connected by a large loop and beta-strand, is located in the Gln-tRNA synthetase within a region that binds the inside corner of the "L"-shaped tRNA molecule. This structural motif contains a long alpha-helix, which extends along the entire length of the D and anticodon stems of the complexed tRNA. We suggest that the positioning of this helix relative to the dinucleotide fold plays a critical role in ensuring the proper global orientation of tRNA(Gln) on the surface of the enzyme. The structural correspondences suggest a similar overall orientation of binding of tRNA(Met) and tRNA(Gln) to their respective synthetases.
Reverse of e-mail spam filtering algorithms to maintain e-mail deliverability (2014)

Over the past years, research has highlighted the importance of enhancing the performance of e-mail spam filters to eliminate the risk of false negative e-mails. On the other hand, the problem of false positive e-mails got less attention despite the fact that it is critical and may cause a failure in the delivery of important e-mails. The aim of this research is to provide a solution to reduce the rate of false positive e-mails. It addresses the problem by exploring the behavior of the existing e-mail spam filters and highlighting the different reasons behind the failure of e-mail delivery. Based on this investigation, we developed an algorithm that helps e-mail users in ensuring the deliverability of their emails. The proposed algorithm is based on reversing the mechanism of spam filters on the client-side.
Positive position feedback control for large space structures (1987)

A new technique for vibration suppression in large space structures is investigated in laboratory experiments on a thin cantilever beam. This technique, called Positive Position Feedback, makes use of generalized displacement measurements to accomplish vibration suppression. Several features of Positive Position Feedback make it attractive for the large space structure control environment: The realization of the controller is simple and straightforward. Global stability conditions can be derived which are independent of the dynamical characteristics of the structure being controlled, i.e., all spillover is stabilizing. The method cannot be destabilized by finite actuator dynamics, and the technique is amenable to a strain-based sensing approach. The experiments control the first six bending modes of a cantilever beam, and make use of piezoelectric materials for actuators and sensors, simulating a piezoelectric active-member. The modal damping ratios are increased by factors ranging from 2 to 130.
Simulation of Ca<sup>2+</sup> persistent inward currents in spinal motoneurones: mode of activation and integration of synaptic inputs (2005)

The goal of this study was to investigate the nature of activation of the dendritic calcium persistent inward current (Ca 2+ PIC) and its contribution to the enhancement and summation of synaptic inputs in spinal motoneurones. A compartmental cable model of a cat α‐motoneurone was developed comprising the realistic dendritic distribution of Ia‐afferent synapses and low‐voltage‐activated L‐type calcium (Ca v 1.3) channels distributed over the dendrites in a manner that was previously shown to match a wide set of experimental measurements. The level of synaptic activation was systematically increased and the resulting firing rate, somatic and dendritic membrane potentials, dendritic Ca v 1.3 channel conductance, and dendritic Ca 2+ PIC were measured. Our simulation results suggest that during cell firing the dendritic Ca 2+ PIC is not activated in an all‐or‐none manner. Instead, it is initially activated in a graded manner with increasing synaptic input until it reaches its full activation level, after which additional increases in synaptic input result in minimal changes in the Ca 2+ PIC (PIC saturated). The range of graded activation of Ca 2+ PIC occurs when the cell is recruited and causes a steep increase in the firing frequency as the synaptic current is increased, coinciding with the secondary range of the synaptic frequency–current ( F – I ) relationship. Once the Ca 2+ PIC is saturated the slope of the F – I relationship is reduced, corresponding to the tertiary range of firing. When the post‐spike afterhyperpolarization (AHP) is blocked, either directly by blocking the calcium‐activated potassium channels, or indirectly by blocking the sodium spikes, the PIC is activated in an all‐or‐none manner with increasing synaptic input. Thus, the AHP serves to limit the depolarization of the cell during firing and enables graded, rather than all‐or‐none, activation of the Ca 2+ PIC. The graded activation of the Ca 2+ PIC with increasing synaptic input results in a graded (linear) enhancement and linear summation of synaptic inputs. In contrast, the saturated Ca 2+ PIC enhances synaptic inputs by a constant amount (constant current), and leads to less‐than linear summation of multiple synaptic inputs. These model predictions improve our understanding of the mode of activation of the dendritic Ca 2+ PIC and its role in the enhancement and integration of synaptic inputs.
Highly Impermeable “Soft” Self-Assembled Monolayers (2000)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTHighly Impermeable "Soft" Self-Assembled MonolayersVijoleta Braach-Maksvytis and Burkhard RaguseView Author Information CSIRO Telecommunication & Industrial Physics PO Box 218, Lindfield, NSW 2070, Australia Cite this: J. Am. Chem. Soc. 2000, 122, 39, 9544–9545Publication Date (Web):September 19, 2000Publication History Received14 March 2000Revised4 August 2000Published online19 September 2000Published inissue 1 October 2000https://pubs.acs.org/doi/10.1021/ja000917yhttps://doi.org/10.1021/ja000917yrapid-communicationACS PublicationsCopyright © Published 2000 by the American Chemical SocietyRequest reuse permissionsArticle Views264Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Defects,Electrodes,Gold,Lipids,Molecules Get e-Alerts
Taxonomic study and fermentation of producing organism and antimicrobial activity of mildiomycin. (1978)

A taxonomic study of strain B-98891, which produced an antibiotic effective against powdery mildew of barley, identified it as Streptoverticillium rimofaciens. On agar media the antibiotic, which was named mildiomycin, was only weakly active against most fungi and bacteria tested. However, it inhibited some Mycobacterium and Rhodotorula, and it showed excellent control of powdery mildew of barley plants in greenhouse tests at concentrations between 31.2 and 62.5 ppm. Rhodotorula rubra IFO 0907 was selected as the test organism for in vitro assay of mildiomycin.
Bacteriophages in the Dairy Environment: From Enemies to Allies (2017)

The history of dairy farming goes back thousands of years, evolving from a traditional small-scale production to the industrialized manufacturing of fermented dairy products. Commercialization of milk and its derived products has been very important not only as a source of nourishment but also as an economic resource. However, the dairy industry has encountered several problems that have to be overcome to ensure the quality and safety of the final products, as well as to avoid economic losses. Within this context, it is interesting to highlight the role played by bacteriophages, or phages, viruses that infect bacteria. Indeed, bacteriophages were originally regarded as a nuisance, being responsible for fermentation failure and economic losses when infecting lactic acid bacteria, but are now considered promising antimicrobials to fight milk-borne pathogens without contributing to the increase in antibiotic resistance.
Association of <scp>RHAMM</scp> with <scp>E2F1</scp> promotes tumour cell extravasation by transcriptional up‐regulation of fibronectin (2014)

Dissemination of cancer cells from primary to distant sites is a complex process; little is known about the genesis of metastatic changes during disease development. Here we show that the metastatic potential of E2F1-dependent circulating tumour cells (CTCs) relies on a novel function of the hyaluronan-mediated motility receptor RHAMM. E2F1 directly up-regulates RHAMM, which in turn acts as a co-activator of E2F1 to stimulate expression of the extracellular matrix protein fibronectin. Enhanced fibronectin secretion links E2F1/RHAMM transcriptional activity to integrin-β1-FAK signalling associated with cytoskeletal remodelling and enhanced tumour cell motility. RHAMM depletion abolishes fibronectin expression and cell transmigration across the endothelial layer in E2F1-activated cells. In a xenograft model, knock-down of E2F1 or RHAMM in metastatic cells protects the liver parenchyma of mice against extravasation of CTCs, whereas the number of transmigrated cells increases in response to E2F1 induction. Expression data from clinical tissue samples reveals high E2F1 and RHAMM levels that closely correlate with malignant progression. These findings suggest a requirement for RHAMM in late-stage metastasis by a mechanism involving cooperative stimulation of fibronectin, with a resultant tumourigenic microenvironment important for enhanced extravasation and distant organ colonization. Therefore, stimulation of the E2F1-RHAMM axis in aggressive cancer cells is of high clinical significance. Targeting RHAMM may represent a promising approach to avoid E2F1-mediated metastatic dissemination.
<i>Salmonella enterica</i>subspecies<i>diarizonae</i>bacteremia in an infant with enteritis: a case report (1991)

The septicemia caused by the Arizona group organism is rare and usually observed in adults with underlying diseases. In Korea, Salmonella infection is common, but a report of Arizona infection is unknown. We isolated S. entercia subsp. diarizonae from blood of a 6-month-old infant. The serovar was determined as 28:z10:-, a rare one in America. The isolate was susceptible to ampicillin, chloramphenicol, cotrimoxazole and others. The patient rapidly recovered with ampicillin and gentamicin therapy. Clinical laboratories should consider that the infection exists in Korea and should attempt to isolate and identify Arizona organism in certain patients.
A Straightforward and Highly Efficient Precipitation/On-Pellet Digestion Procedure Coupled with a Long Gradient Nano-LC Separation and Orbitrap Mass Spectrometry for Label-Free Expression Profiling of the Swine Heart Mitochondrial Proteome (2009)

For label-free expression profiling of tissue proteomes, efficient protein extraction, thorough and quantitative sample cleanup and digestion procedures, as well as sufficient and reproducible chromatographic separation, are highly desirable but remain challenging. However, optimal methodology has remained elusive, especially for proteomes that are rich in membrane proteins, such as the mitochondria. Here, we describe a straightforward and reproducible sample preparation procedure, coupled with a highly selective and sensitive nano-LC/Orbitrap analysis, which enables reliable and comprehensive expression profiling of tissue mitochondria. The mitochondrial proteome of swine heart was selected as a test system. Efficient protein extraction was accomplished using a strong buffer containing both ionic and nonionic detergents. Overnight precipitation was used for cleanup of the extract, and the sample was subjected to an optimized 2-step, on-pellet digestion approach. In the first step, the protein pellet was dissolved via a 4 h tryptic digestion under vigorous agitation, which nano-LC/LTQ/ETD showed to produce large and incompletely cleaved tryptic peptides. The mixture was then reduced, alkylated, and digested into its full complement of tryptic peptides with additional trypsin. This solvent precipitation/on-pellet digestion procedure achieved significantly higher and more reproducible peptide recovery of the mitochondrial preparation than observed using a prevalent alternative procedure for label-free expression profiling, SDS-PAGE/in-gel digestion (87% vs 54%). Furthermore, uneven peptide losses were lower than observed with SDS-PAGE/in-gel digestion. The resulting peptides were sufficiently resolved by a 5 h gradient using a nano-LC configuration that features a low-void-volume, high chromatographic reproducibility, and an LTQ/Orbitrap analyzer for protein identification and quantification. The developed method was employed for label-free comparison of the mitochondrial proteomes of myocardium from healthy animals versus those with hibernating myocardium. Each experimental group consisted of a relatively large number of animals (n = 10), and samples were analyzed in random order to minimize quantitative false-positives. With this approach, 904 proteins were identified and quantified with high confidence, and those mitochondrial proteins that were altered significantly between groups were compared with the results of a parallel 2D-DIGE analysis. The sample preparation and analytical strategy developed here represents an advancement that can be adapted to analyze other tissue proteomes.
Prognostic Factors for Local Control and Survival of Cancer of the Oral Tongue a retrospective analysis of 230 cases in Western Sweden (1993)

During the 19-year period from 1970 to 1988, 289 cases of squamous cell carcinoma of the oral tongue were diagnosed in Western Sweden. In 230 of these, treatment regimens and results were analysed in an attempt to define prognostic factors for local control and survival. Tumour stages were: T1 26%, T2 32%, T3 30% and T4 13%. Nodal disease was seen in 32% of the patients. Sixty per cent of the patients had surgery, 74% external with or without combination with interstitial irradiation; and 32% received chemotherapy. The local control rate at five years was 59% (T1 66%, T2 67%, T3 44% and T4 0%). Survival at five years was 37% (T1 61%, T2 51%, T3 19% and T4 0%). By a multivariate procedure we demonstrate that the tumour related variables T-category, N-category and extension to the tonsillar region had a significant association with survival. Extension to the tonsillar region, extension to the floor of the mouth and level of neck nodes were significantly associated with local-regional control.
Intravenous nicardipine in cats increases optic nerve head but not retinal blood flow. (1992)

The effect of intravenously injected nicardipine on retinal and optic nerve head (ONH) blood flow was studied in 27 cats using laser Doppler velocimetry and flowmetry, respectively. A dose of 20 micrograms/kg of nicardipine had little effect on retinal blood flow. A dose of 100 micrograms/kg, however, produced a significant transient decrease in flow. By contrast, both doses produced a significant increase in ONH blood flow despite a significant decrease of the mean arterial blood pressure. Measurements of the partial pressure of oxygen (PO2) with an oxygen-sensitive microelectrode, whose tip was placed in the vitreous just in front of the optic disc, showed a significant increase in the PO2 that paralleled the increase in ONH blood flow. These results demonstrate, for the first time to the authors' knowledge, a pharmacologically induced increase in ONH blood flow and suggest that nicardipine could have a beneficial effect on ONH tissue.