gebhart/patrepeval huggingface dataset:
Wiener Filters (1996)

Wiener theory, formulated by Norbert Wiener, forms the foundation of data-dependent linear least squared error filters. Wiener filters play a central role in a wide range of applications such as linear prediction, signal coding, echo cancellation, signal restoration, channel equalisation, system identification etc. The coefficients of a Wiener filter are calculated to minimise the average squared distance between the filter output and a desired signal. In its basic form, the Wiener theory assumes that the signals are stationary processes. However, if the filter coefficients are periodically recalculated, for every block of N samples, then the filter adapts to the average characteristics of the signals within the blocks and becomes block-adaptive. A block-adaptive filter can be used for signals that can be considered stationary over the duration of the block. In this chapter we study the theory of Wiener filters, and consider alternative methods of formulation of the Wiener filter problem. We consider the application of Wiener filters in channel equalisation, time-delay estimation, and additive noise suppression. A case study of the frequency response of a Wiener filter, for additive noise reduction, provides useful insight into the operation of the filter. We also deal with some implementation issues of Wiener filters.
Relationship between creativity and classroom behavior (1980)

A relationship between creativity and misbehavior in the classroom often has been presumed by educators, but actually has had little substantiation. The present study attempts to clarify the dynamics of that relationship by determining the extent to which creativity test scores predict identification of students by teachers and/or peers as misbehavers. Intercorrelations between creativity subtests and peer perception of creative behavior suggest that students high in elaboration and in originality are more likely to be described by peers as exhibiting creative behavior. Results generally failed to support that high creativity scores predict teacher identification of students as behavior problems. However, the sociometric variables of popularity and misbehavior were significantly correlated with high creativity scores. Implications for further study are discussed.
Robust visual tracking for non-instrumental augmented reality (2003)

This paper presents a robust and flexible framework for augmented reality which does not require instrumenting either the environment or the workpiece. A model-based visual tracking system is combined with rate gyroscopes to produce a system which can track the rapid camera rotations generated by a head-mounted camera, even if images are substantially degraded by motion blur. This tracking yields estimates of head position at video field rate (50Hz) which are used to align computer-generated graphics on an optical see-through display. Nonlinear optimisation is used for the calibration of display parameters which include a model of optical distortion. Rendered visuals are pre-distorted to correct the optical distortion of the display.
Biologic therapy for psoriasis: the T-cell-targeted therapies efalizumab and alefacept. (2003)

During the past several years, a new generation of therapies for psoriasis has been in development. These biologic therapies target the activity of T lymphocytes and cytokines responsible for the inflammatory nature of this disease. The first article of this 2-part update reviewed the tumor necrosis factor (TNF) inhibitors, infliximab and etanercept. In this article, we will review 2 therapies that target the T cell, efalizumab and alefacept.
Palladium‐Catalyzed Asymmetric Intermolecular Cyclization (2013)

Domino cyclization: Alkylpalladium intermediates in an asymmetric Heck reaction were intercepted by a second alkene to give tricyclic products with high enantioselectivity (see scheme; Boc=tert-butoxycarbonyl). The method was applied to the asymmetric synthesis of a precursor of (−)-martinellic acid, a folk eye medicine in South America.
Inhibition of water condensation by a soluble salt nucleus (1981)

In heterogeneous condensation of water vapor on an insoluble solid surface, the presence of a soluble salt crystal has two effects. The first is the well-known effect as a nucleus for condensation at low supersaturation. We show that it also inhibits condensation around it by reducing the concentration of adsorbed molecules. This effect extends to macroscopic distances.
Trading quality for compile time (1999)

Article Trading quality for compile time: ultra-fast placement for FPGAs Share on Authors: Yaska Sankar Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada M5S 3G4 Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada M5S 3G4View Profile , Jonathan Rose Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada M5S 3G4 Department of Electrical and Computer Engineering, University of Toronto, Toronto, ON, Canada M5S 3G4View Profile Authors Info & Claims FPGA '99: Proceedings of the 1999 ACM/SIGDA seventh international symposium on Field programmable gate arraysFebruary 1999 Pages 157–166https://doi.org/10.1145/296399.296449Online:01 February 1999Publication History 68citation515DownloadsMetricsTotal Citations68Total Downloads515Last 12 Months7Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Potassium Channel Antagonists Influence Porcine Granulosa Cell Proliferation, Differentiation, and Apoptosis1 (2002)

This investigation determined the effects of K(+) channel antagonists on proliferation, differentiation, and apoptosis of porcine granulosa cells. The drugs screened for functional effects included the class III antiarrhythmic agents MK-499 and clofilium, the chromanol I(Ks) antagonist 293B, the benzodiazepine I(Ks) antagonists L-735,821 and L-768,673, and the peptidyl toxins charybdotoxin (CTX) and margatoxin (MTX). Granulosa cell proliferation and differentiation were assessed by serial measurements of cell number and progesterone accumulation in the culture media, respectively. Granulosa cell apoptosis was evaluated using flow cytometry. Additional information about drug effects was obtained by immunoblotting to detect expression of proliferating cell nuclear antigen, p27(kip1) and the caspase-3 substrate poly(ADP-ribose) polymerase. The ERG channel antagonist MK-499 had no functional effects on cultured granulosa cells. However, the broad spectrum K(+) channel antagonist clofilium decreased, in a concentration-dependent fashion, the number of viable granulosa cells cultured, and these effects were associated with induction of apoptosis. All three I(Ks) antagonists (293B, L-735,821, and L-768,673) increased basal, but not FSH-enhanced progesterone accumulation on Day 1 after treatment without affecting the number of viable cells in culture, an effect that was blocked by pimozide. In contrast, CTX and MTX increased the number of viable cells in FSH-stimulated cultures on Day 3 after treatment without affecting progesterone output per cell. These data demonstrate that selective antagonism of granulosa cell K(+) channels with distinct molecular correlates, electrophysiological properties, and expression patterns can influence differential granulosa cell proliferation, steroidogenic capability, and apoptosis. Thus, K(+) channels may represent pharmacological targets for affecting Granulosa cell function and oocyte maturation, in vivo or in vitro.
Quantification of growth and differentiation of C2C12 skeletal muscle cells on PSS–PAH-based polyelectrolyte layer-by-layer nanofilms (2011)

Polyelectrolyte layer-by-layer (LbL) nanofilms are interesting polymeric structures, built by alternating adsorption of positively and negatively charged polyelectrolytes. They consist of multilayer sheets with nanometric overall thickness, and they can be used as supports and surface coatings for in vitro and in vivo cell and tissue growth and regeneration. The present study focuses on nanofilms based on alternated layers of poly(sodium-4-sulfonate) (PSS) and poly(allylamine hydrochloride) (PAH) fabricated using spin-assisted LbL assembly (SA-LbL). The fabrication process used to assemble polyelectrolyte nanofilms made of up to 60 bilayers is described, and the influence of different surface charges (i.e. changing the terminal layer) and of different film composition (e.g. varying PSS molecular weight) on cell behaviour is investigated. In particular, C2C12 skeletal muscle cells' viability, proliferation and differentiation on six different typologies of polyelectrolyte nanofilms are evaluated and quantified, giving a reference for skeletal muscle regeneration capabilities on such kind of structures.
Immunology of Psoriasis (2014)

The skin is the front line of defense against insult and injury and contains many epidermal and immune elements that comprise the skin-associated lymphoid tissue (SALT). The reaction of these components to injury allows an effective cutaneous response to restore homeostasis. Psoriasis vulgaris is the best-understood and most accessible human disease that is mediated by T cells and dendritic cells. Inflammatory myeloid dendritic cells release IL-23 and IL-12 to activate IL-17-producing T cells, Th1 cells, and Th22 cells to produce abundant psoriatic cytokines IL-17, IFN-γ, TNF, and IL-22. These cytokines mediate effects on keratinocytes to amplify psoriatic inflammation. Therapeutic studies with anticytokine antibodies have shown the importance of the key cytokines IL-23, TNF, and IL-17 in this process. We discuss the genetic background of psoriasis and its relationship to immune function, specifically genetic mutations, key PSORS loci, single nucleotide polymorphisms, and the skin transcriptome. The association between comorbidities and psoriasis is reviewed by correlating the skin transcriptome and serum proteins. Psoriasis-related cytokine-response pathways are considered in the context of the transcriptome of different mouse models. This approach offers a model for other inflammatory skin and autoimmune diseases.
A Host-Agnostic, Supervised Machine Learning Approach to Automated Overload Detection in Virtual Machine Workloads (2017)

This paper evaluates a mechanism for applying machine learning (ML) to identify over-constrained IaaS virtual machines (VMs). Herein, over-constrained VMs are defined as those who are not given sufficient system resources to meet their workload specific objective functions. To validate our approach, a variety of workload-specific benchmarks inspired by common Infrastructure-as-a-Service (IaaS) cloud workloads were used. Workloads were run while regularly sampling VM resource consumption features exposed by the hypervisor. Datasets were curated into nominal or over-constrained and used to train ML classifiers to determine VM over-constraint rules based on one-time workload analysis. Rules learned on one host are transferred with the VM to other host environments to determine portability. Key contributions of this work include: demonstrating which VM resource consumption metrics (features) prove most relevant to learned decision trees in this context, and a technique required to generalize this approach across hosts while limiting required up front training expenditure to a single VM and host. Other contributions include a rigorous explanation of the differences in learned rulesets as a function of feature sampling rates, and an analysis of the differences in learned rulesets as a function of workload variation. Feature correlation matrices and their corresponding generated rule sets demonstrate individual features comprising rule sets tend to show low cross-correlation (below 0.4) while no individual feature shows high direct correlation with classification. Our system achieves workload-specific error percentages below 2.4% with a mean error across workloads of 1.43% (and strong false negative bias) for a variety of synthetic, representative, cloud workloads tested.
OWL 2 Web Ontology Language Direct Semantics (2009)

The OWL 2 Web Ontology Language, informally OWL 2, is an ontology language for the Semantic Web with formally defined meaning. OWL 2 ontologies provide classes, properties, individuals, and data values and are stored as Semantic Web documents. OWL 2 ontologies can be used along with information written in RDF, and OWL 2 ontologies themselves are primarily exchanged as RDF documents. The OWL 2 Document Overview describes the overall state of OWL 2, and should be read before other OWL 2 documents. This document provides the direct model-theoretic semantics for OWL 2, which is compatible with the description logic SROIQ. Furthermore, this document defines the most common inference problems for OWL 2.
Differentiable Algorithm Networks for Composable Robot Learning (2019)

This paper introduces the Differentiable Algorithm Network (DAN), a composable architecture for robot learning systems. A DAN is composed of neural network modules, each encoding a differentiable robot algorithm and an associated model; and it is trained end-to-end from data. DAN combines the strengths of model-driven modular system design and data-driven end-to-end learning. The algorithms and models act as structural assumptions to reduce the data requirements for learning; endto-end learning allows the modules to adapt to one another and compensate for imperfect models and algorithms, in order to achieve the best overall system performance. We illustrate the DAN methodology through a case study on a simulated robot system, which learns to navigate in complex 3-D environments with only local visual observations and an image of a partially correct 2-D floor map. Model Algorithm filter Data Algorithm planner !"#$%&'()!* '+()!* ,$'%* Algorithm control Model Model Data ,$'%
Infrared studies of the normal and superconducting states of Y<sub>1</sub>Ba<sub>2</sub>Cu<sub>3</sub>O<sub>7</sub> (1989)

We describe infrared measurements of the a-b-plane response of Y <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</inf> Ba <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> Cu <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">7</inf> crystals with T <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> ≃ 92 K. We observe a self-energy structure at a characteristic energy of 500 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−1</sup> (8kT <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> ), the appearance of which coincides with the transition to the superconducting state. The nature of this self-energy anomaly is consistent with its identification as a nodeless a-b-plane energy gap at 2Δ ≃ 8kT <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> . On the basis of temperature-dependent measurements above T <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> , we suggest that the normal state can be primarily characterized by a carrier band with an enhanced low-frequency mass and a frequency-dependent scattering rate. Our data indicate that these arise from coupling to an excitation spectrum with characteristic frequencies up to ω <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> ∼ 700 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−1</sup> and a coupling strength of λ ≃ 2–3.
Two-dimensional tracking and TDI are consistent methods for evaluating myocardial longitudinal peak strain in left and right ventricle basal segments in athletes (2007)

Provided that echographic imaging is good, strain can be computed in athletes by both Doppler-derived and tracking methods. It is technically feasible to use both -interchangeably, at least in basal segments.
Diagnostic value of circulating miR-21: An update meta-analysis in various cancers and validation in endometrial cancer (2016)

MiR-21 has been identified as one of the most common proto-oncogenes. It is hypothesized that up-regulated miR-21 could be served as a potential biomarker for human cancer diagnosis. However, inconsistencies or discrepancies about diagnostic accuracy of circulating miR-21 still remain. In this sense, miR-21's diagnostic value needs to be fully validated. In this study, we performed an update meta-analysis to estimate the diagnostic value of circulating miR-21 in various human cancers. Additionally, we conducted a validation test on 50 endometrial cancer patients, 50 benign lesion patients and 50 healthy controls. A systematical literature search for relevant articles was performed in Pubmed, Embase and Cochrane Library. A total of 48 studies from 39 articles, involving 3,568 cancer patients and 2,248 controls, were included in this meta-analysis. The overall sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR) and area under the curve (AUC) were 0.76 (0.71-0.80), 0.82 (0.79-0.85), 4.3 (3.6-5.1), 0.29 (0.24-0.35), 15 (11-20) and 0.86 (0.83-0.89), respectively. In the validation test, the expression levels of serum miR-21 were significantly higher in benign lesion patients (p = 0.003) and endometrial cancer patients (p = 0.000) compared with that of healthy controls. Endometrial cancer patients showed higher miR-21 expression levels (p = 0.000) compared with benign lesion patients. In conclusion, the meta-analysis shows that circulating miR-21 has excellent performance on the diagnosis for various cancers and the validation test demonstrates that serum miR-21 could be served as a novel biomarker for endometrial carcinoma.
[A new mutation in COL1A1 gene in a family with osteogenesis imperfecta]. (2006)

This is the first delineation of an aspartic acid substitution in new site of the a1 (I) chain causing nonlethal osteogenesis imperfecta. Only nine aspartic acid substitution in type I collagen has been fully reported in the world. Now we revealed a new nosogenesis of OI. Since only few of nucleotide changes in type I collagen glycine codons would result in an aspartic acid substitution, these are predicted to be infrequent. Furthermore, it is possible to suggest that nosogenesis of OI in china is different from other countries.
The fair shaper: an efficient mechanism for Internet bandwidth share over ATM in a multitasks OS (2002)

In this paper we propose a solution that integrates traffic shaping with fair queueing into a single scheduling algorithm. The proposed algorithm called "fair shaping mechanism" is used to manage bandwidth on ATM virtual channels in non real time network terminals. It takes into account the general expression of ATM traffic parameters. We discuss the necessary modifications of these parameters for bursty IP traffic. A leaky bucket model is used to shape this traffic and a packet-to-cell parameter conversion is proposed. We present an implementation prototype of this server in the IP driver for a Solaris 2.5 operating system (OS).
Screening, library‐assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization (2004)

A liquid chromatographic/mass spectrometric assay with atmospheric pressure chemical ionization (LC/APCI-MS) is presented for fast and reliable screening and identification and also for precise and sensitive quantification in plasma of the 23 benzodiazepines alprazolam, bromazepam, brotizolam, camazepam, chlordiazepoxide, clobazam, clonazepam, diazepam, flunitrazepam, flurazepam, desalkylflurazepam, lorazepam, lormetazepam, medazepam, metaclazepam, midazolam, nitrazepam, nordazepam, oxazepam, prazepam, temazepam and tetrazepam, triazolam, their antagonist flumazenil and the benzodiazepine BZ1 (omega 1) receptor agonists zaleplone, zolpidem and zopiclone. It allows confirmation of the diagnosis of an overdose situation and monitoring of psychiatric patients' compliance. The analytes were isolated from plasma using liquid-liquid extraction and were separated on a Merck LiChroCART column with Superspher 60 RP Select B as the stationary phase. Gradient elution was performed using aqueous ammonium formate and acetonitrile. After screening and identification in the scan mode using the authors' LC/MS library, the analytes were quantified in the selected-ion monitoring mode. The quantification assay was fully validated. It was found to be selective proved to be linear from sub-therapeutic to over therapeutic concentrations for all analytes, except bromazepam. The corresponding reference levels the assay's accuracy and precision data for all studied substances are listed. The accuracy and precision data were within the required limits with the exception of those for bromazepam. The analytes were stable in frozen plasma for at least 1 month. The validated assay was successfully applied to several authentic plasma samples from patients treated or intoxicated with various benzodiazepines or with zaleplone, zolpidem or zopiclone. It has proven to be appropriate for the isolation, separation, screening, identification and quantification of the drugs mentioned above in plasma for clinical toxicology, e.g. in cases of poisoning, and forensic toxicology, e.g. in cases of driving under the influence of drugs.
Disintegration as a key-step in sewage sludge treatment (2000)

Fields of application of the mechanical sewage sludge disintegration are presented. Various methods of mechanical cell disintegration are described and the obtained results are compared. All methods are able to break up the flocs, but only some of them provide enough energy for the disruption of micro-organisms. The possible improvement of the anaerobic degradation process using raw sludge, excess sludge and digested sludge is shown. Excesssludge proves to be the most suitable. The use of disintegrated sludge as a carbon source for the denitrification is explained as a second field of application. External carbon sources can be substituted and the amount of sewage sludge to be disposed of is reduced at the same time. Foamingin digesters caused by filamentous micro-organisms can be reduced by disintegration of these sludges. Adsorbed gas bubbles are released and the settling properties of the sludge are improved. Another field of application is the solution of organic components of the sludge solids. The increased concentration of nitrogen and phosphorous in the supernatant causes recovery processes to be operated at a higher cost efficiency. A comparison of effort and advantages shows that disintegration is especially useful if there are problems in the sludge treatment process of the WTP.