gebhart/patrepeval huggingface dataset:
A Vertical W-band Surface-Micromachined Yagi-Uda Antenna (2005)

A vertical W-band surface-micromachined Yagi-Uda monopole array is proposed and implemented for the first time. The monopoles stand on a high-k soda-lime glass substrate and are fed by a coplanar waveguide. The geometry functions as a vertically placed Yagi-Uda antenna due to the image theory. The performance of the vertical Yagi-Uda is to be superior to conventional W-band printed antennas due to minimum substrate wave effects. A successful implementation of the vertical Yagi-Uda structure is demonstrated using high-aspect-ratio surface micromachining fabrication technologies. The test results of a 5 element structure demonstrate a 10-dB-impedance-bandwidth of 12% at 100 GHz. A directivity of 8.2 dBi is projected for this prototype.
Die Kapillarkurve der höheren Fettsäuren und die Zustandsgleichung der Oberflächenschicht (1925)

Article Die Kapillarkurve der höheren Fettsäuren und die Zustandsgleichung der Oberflächenschicht was published on May 1, 1925 in the journal Zeitschrift für Physikalische Chemie (volume 116U, issue 1).
NMR Structure of the [2Fe-2S] Ferredoxin Domain from Soluble Methane Monooxygenase Reductase and Interaction with Its Hydroxylase<sup>,</sup> (2001)

The soluble methane monooxygenase (sMMO) from Methylococcus capsulatus (Bath) is a multicomponent enzyme system required for the conversion of methane to methanol. It comprises a hydroxylase, a regulatory protein, and a reductase. The reductase contains two domains: an NADH-binding and FAD-containing flavin domain and a ferredoxin (Fd) domain carrying a [2Fe-2S] cofactor. Here, we report the solution structure of the reduced form of the 98-amino acid Fd domain (Blazyk, J. L., and Lippard, S. J. Unpublished results) determined by nuclear magnetic resonance (NMR) spectroscopy and restrained molecular dynamics calculations. The structure consists of six beta strands arranged into two beta sheets as well as three alpha helices. Two of these helices form a helix-proline-helix motif, unprecedented among [2Fe-2S] proteins. The [2Fe-2S] cluster is coordinated by the sulfur atoms of cysteine residues 42, 47, 50, and 82. The 10.9 kDa ferredoxin domain of the reductase protein transfers electrons to carboxylate-bridged diiron centers in the 251 kDa hydroxylase component of sMMO. The binding of the Fd domain with the hydroxylase was investigated by NMR spectroscopy. The hydroxylase binding surface on the ferredoxin protein has a polar center surrounded by patches of hydrophobic residues. This arrangement of amino acids differs from that by which previously studied [2Fe-2S] proteins interact with their electron-transfer partners. The critical residues on the Fd domain involved in this binding interaction map well onto the universally conserved residues of sMMO enzymes from different species. We propose that the [2Fe-2S] domains in these other sMMO systems have a fold very similar to the one found here for M. capsulatus (Bath) MMOR-Fd.
Neurophysiological Model of the Normal and Abnormal Human Pupil (1985)

A model of the pathways controlling the size of the human pupil is presented. Computer simulation of this model demonstrates the role played by each of the elements in the pupil pathways. Simulations of the effects of drugs and a few common abnormalities in the system also help to illustrate the workings of the internal processes. Computer models of this type can be used as teaching aids or as tools for testing of hypotheses regarding the system.
A Porphyrin Prism: Structural Switching Triggered by Guest Inclusion (2001)

A prismlike hollow structure was assembled when three pyridyl-substituted porphyrin panels were linked by six PdII ions. A dramatic D3h→C2 structural change of the prism (see scheme) was triggered by complexation of pyrene.
A study of roundabout traffic flow distribution based on the attraction of land use (2012)

In order to gain the circling volume and weaving volume to evaluate the roundabout operation, the traffic flow distribution must be calculated or investigated. The distribution is related with the volume of the entry and exit, and also related with the land-use attraction of the exit. The relation above mentioned is the same as gravity model of the traffic generation. Therefore the attraction matrix was introduced as the general traffic impedance matrix, the daul-constraints gravity model is modified. Taking the Shuma Guangchang −4 legs roundabout in Dalian as the example and basis on the investigation data, the distribution was calculated by the equations and by modified gravity model. The average error of the modified gravity model was 3% in comparison with two calculation results. It was concluded that the dual-constraints gravity model based on the land-use could be used for the distribution of roundabout traffic flow.
Percutaneous Irreversible Electroporation for Treatment of Small Hepatocellular Carcinoma Invisible on Unenhanced CT: A Novel Combined Strategy with Prior Transarterial Tumor Marking (2021)

Ethiodized oil tumor marking enables to demarcate small HCCs that were invisible on unenhanced CT. It potentially allows a safe and complete ablation in subsequent CT-guided IRE.
β-Adrenergic Receptor Antagonists Accelerate Skin Wound Healing (2006)

The skin is our primary defense against noxious environmental agents. Upon injury, keratinocytes migrate directionally into the wound bed to initiate re-epithelialization, essential for wound repair and restoration of barrier integrity. Keratinocytes express a high level of beta2-adrenergic receptors (beta2-ARs) that appear to play a role in cutaneous homeostasis as aberrations in either keratinocyte beta2-AR function or density are associated with various skin diseases. Here we report the novel finding that beta-AR antagonists promote wound re-epithelialization in a "chronic" human skin wound-healing model. beta-AR antagonists increase ERK phosphorylation, the rate of keratinocyte migration, electric field-directed migration, and ultimately accelerate human skin wound re-epithelialization. We demonstrate that keratinocytes express two key enzymes required for catecholamine (beta-AR agonist) synthesis, tyrosine hydroxylase and phenylethanolamine-N-methyl transferase, both localized within keratinocyte cytoplasmic vesicles. Finally, we confirm the synthesis of epinephrine by measuring the endogenously synthesized catecholamine in keratinocyte extracts. Previously, we have demonstrated that beta-AR agonists delay wound re-epithelialization. Here we report that the mechanism for the beta-AR antagonist-mediated augmentation of wound repair is due to beta2-AR blockade, preventing the binding of endogenously synthesized epinephrine. Our work describes an endogenous beta-AR mediator network in the skin that can temporally regulate skin wound repair. Further investigation of this network will improve our understanding of both the skin repair process and the multiple modes of action of one of the most frequently prescribed class of drugs, hopefully resulting in a new treatment for chronic wounds.
Effects of Water Activity, Light Intensity and Physical Structure of Food on the Kinetics of Riboflavin Photodegradation (1984)

ABSTRACT The kinetics of light‐induced riboflavin degradation were evaluated in elbow macaroni, particulate macaroni, nonfat dried milk, skim milk and a buffered solution of riboflavin. A first order degradative mechanism was observed in liquid systems, while a two‐phased mechanism was observed in dry food systems. Light intensities of 25, 50 or 100 ft‐c showed no significant differences in effect on the rate of riboflavin loss in elbow macaroni; however, a very dim light showed only a single‐phased first order rate of loss. In elbow macaroni exposed to a broad range of water activities the degradation of riboflavin increased at elevated relative humidities. Lumichrome was determined to have limited use as a quantitative indicator of riboflavin loss, but could be used as a qualitative indicator of riboflavin degradation.
Moving Convolutional Neural Networks to Embedded Systems: The AlexNet and VGG-16 Case (2018)

Execution of deep learning solutions is mostly restricted to high performing computing platforms, e.g., those endowed with GPUs or FPGAs, due to the high demand on computation and memory such solutions require. Despite the fact that dedicated hardware is nowadays subject of research and effective solutions exist, we envision a future where deep learning solutions -here Convolutional Neural Networks (CNNs)- are mostly executed by low-cost off-the shelf embedded platforms already available in the market. This paper moves in this direction and aims at filling the gap between CNNs and embedded systems by introducing a methodology for the design and porting of CNNs to limited in resources embedded systems. In order to achieve this goal we employ approximate computing techniques to reduce the computational load and memory occupation of the deep learning architecture by compromising accuracy with memory and computation. The proposed methodology has been validated on two well-know CNNs, i.e., AlexNet and VGG-16, applied to an image-recognition application and ported to two relevant off-the-shelf embedded platforms.
Surface modification of carbon and platinum electrodes using TiCl4 (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface modification of carbon and platinum electrodes using TiCl4Stanton Ching, Raymond C. Dudek, Elie A. Tabet, William S. Willis, and Steven L. SuibCite this: Langmuir 1994, 10, 6, 1657–1659Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/la00018a007https://doi.org/10.1021/la00018a007research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Use of 5-bromo-4-chloro-3-indolyl-β-D-galactopyranoside for the isolation of β-galactosidase-positive bacteria from municipal water supplies (1993)

A new medium, mX-Gal, has been developed for the membrane filter enumeration of beta-galactosidase-positive bacteria in municipal water supplies. mX-Gal medium contains the chromogenic beta-galactosidase substrate 5-bromo-4-chloro-3-indolyl-beta-D-galactopyranoside (X-Gal). All Aeromonas, Citrobacter, and Enterobacter strains isolated from raw water on mX-Gal medium were beta-galactosidase positive. In contrast, only 10 to 20% of these strains produced a red colony with a metallic sheen on m-Endo agar LES medium. Of 674 chlorinated water samples analyzed for total coliforms on m-Endo agar LES medium and for beta-galactosidase-positive bacteria on mX-Gal medium, 18 that were negative for coliforms on m-Endo agar LES showed beta-galactosidase-positive bacteria on mX-Gal. Of a total of 50 beta-galactosidase-positive bacteria isolated from these samples, 76% were identified as Aeromonas hydrophila.
Role of Cysteine-82 in the Catalytic Mechanism of Human <i>S</i>-Adenosylmethionine Decarboxylase (1999)

S-Adenosylmethionine decarboxylase is a pyruvate-dependent enzyme. The enzyme forms a Schiff base with substrate, S-adenosylmethionine, through the pyruvoyl moiety. This facilitates the release of CO2 from the substrate, which must then be protonated on the alpha carbon in order to permit hydrolysis of the Schiff base to release the product. The catalytic mechanism of human S-adenosylmethionine decarboxylase was investigated via mutagenic and kinetic approaches. The results of enzyme kinetic studies indicated that Cys-82 is a crucial residue for activity and this residue has a basic pKa. Iodoacetic acid inhibited wild-type enzyme activity in a time- and pH-dependent manner but did not affect the already reduced activity of mutant C82A. Reaction of this mutant with iodoacetic acid led to approximately one less mole of reagent being incorporated per mole of enzyme alphabeta dimer than with wild-type S-adenosylmethionine decarboxylase. Both wild-type and C82A mutant S-adenosylmethionine decarboxylases were inactivated by substrate-mediated transamination, but this reaction occurred much more frequently with C82A than with wild-type enzyme. A major proportion of the recombinant C82A mutant protein was in the transaminated form in which the pyruvoyl cofactor is converted into alanine. This suggests that incorrect protonation of the pyruvate, rather than the substrate, occurs much more readily when Cys-82 is altered. On the basis of these results, it was postulated that residue Cys-82 may be the proton donor of the decarboxylation reaction catalyzed by S-adenosylmethionine decarboxylase.
Line-of-sight MIMO for microwave links - Adaptive dual polarized and spatially separated systems (2009)

With mass uptake of mobile broadband such as HSPA, LTE and advanced LTE there will be a rapid increase of demand for capacity in the mobile backhaul.The traditional frequency bands used for mobile backhaul microwave links are narrow and may become a future capacity bottleneck.Line-of-sight MIMO is one possible technology for increasing the spectral eciency of these links.By using multiple antennas at both the transmitter and receiver the capacity of such systems could be multiplied using the same spectrum.Line-of-sight MIMO works by making the signal streams orthogonal to each other either by spatially separating the antennas at the transmitter and receiver or by using orthogonally polarized antennas.In this thesis both 2x2 spatially-separated and 4x4 spatially-separated and dual-polarized line-of-sight MIMO are numerically investigated.Adaptive algorithms for a space-timeequalizer are proposed and evaluated against detrimental aects such as frequency selective channels, mast swing (antenna movement), polarization leakage and phase noise (correlated and dierential).The algorithms are either decision-directed or blind, those are LMS and WRLS and CMA, SCMA and MCMA respectively.The simulations show that line-of-sight MIMO needs higher system margins and a more complex receiver structure.Convergence of blind algorithms can be dicult to achieve for some channel conditions as well as for dierential phase noise.Mast swing will further more put higher requirements on spatially-separated MIMO systems than on its SISO counterpart.1
Vessel wall heparan sulfate and transcapillary passage of albumin in experimental diabetes in the rat. (1997)

These data indicate that in one-year diabetic rats albuminuria coincides with an increased TERalb and RCalb in most, but not all tissues, and that alterations in basement membrane HS content correlate with changes in the RCalb, which suggests a functional relationship.
Adaptive Hermite models for ECG data compression: performance and evaluation with automatic wave detection (2002)

An orthogonal transformation based on Hermite functions is proposed as a method for ECG data compression. In order to apply the procedure four signal windows are selected in each beat, corresponding to the principal ECG features: P wave, QRS complex, ST segment and T wave. The performance of the method is analysed calculating the compression ratio (CR) and the relative mean-square error (MSE) in each window and in the whole beat. The method has been applied to ECG records from MIT/BIH arrhythmia database. In normal beats with a CR=11.6, the authors have obtained a MSE=(0.09/spl plusmn/0.02)%. In ECG signals containing normal beats and multiform PVCs a MSE=(0.56/spl plusmn/3.41)% is obtained, with a CR=10.3. To analyse the clinical applicability of the method, the algorithm was evaluated with an automatic wave detection program. Differences between the automatic measures in the original signal and in the reconstructed signal were compared and shown a good agreement.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Analysis of Phosphorylation-Dependent Protein-Protein Interactions Using a Bacterial Two-Hybrid System (2002)

Phosphorylation-dependent protein-protein interactions provide the foundation for a multitude of intracellular signal transduction pathways. One of the goals of signal transduction research is to more precisely understand the nature of these phosphorylation-dependent interactions. Here, we describe a bacterial two-hybrid assay that allows for the rapid, efficient analysis of phosphorylation-dependent protein-protein interactions. In this system, the interacting protein domains are provided as fusion proteins in Escherichia coli. cells that contain a eukaryotic kinase. Specific phosphorylation of one of the fused protein domains results in a protein-protein interaction that can be detected as a change in the expression of a reporter gene. We also describe how this system can be modified to permit the use of cDNA libraries to identify either novel binding partners for a phosphorylated substrate or novel kinases that can induce a specific protein-protein interaction.
Signal enhancement in a near-field MIMO environment through adaptivity on transmit and polarization diversity (2008)

In this paper a technique is presented on how to enhance the received signals in a near field multi-input multi-output (MIMO) environment where beam forming is not possible. This is done through the use of adaptivity on transmit. Polarization diversity can also be implemented. This technique is based on the principle of reciprocity, is independent of the material medium in which it is transmitting, and incorporates near-field environments and multipath. The objective here is to select a set of weights adapted to each receiver to be applied to each transmitting antenna array, which is a function of the user location, so that the transmitted signal at the carrier frequency may be directed to a particular receiver location while simultaneously minimizing the received signal strengths at other receiver locations. Numerical simulations have been made to illustrate the novelty of the proposed approach.
Composition, structure, and wear resistance of TiAlOC coatings deposited by chemical vapor deposition (1986)

The deposition of TiwAlxOyCz (TiAlOC) coatings onto cemented tungsten carbide cutting tool inserts by chemical vapor deposition is reported. The TiAlOC coatings are shown to exist in three phase regions: a single‐phase TiAlOC solid solution, a mixture of TiAlOC solid solution and α‐Al2O3, and a mixture of TiC and α‐Al2O3. The wear resistance of coatings from each phase region versus standard commercial coatings is reported.
Fish Oil Metabolites: Translating Promising Findings from Bench to bedside to Reduce Cardiovascular Disease (2011)

Cardiovascular disease is an inflammatory process and the leading cause of death in the United States. Novel omega-3 derived potent lipid mediators, termed resolvins and protectins, have been identified as major pathophysiologic players in the resolution phase of the inflammatory response. Potent lipid mediators offer tremendous metabolic and pathophysiologic insights in regard to the risk and treatment of cardiovascular disease. In this review, resolvins and protectins are described and analyzed as accelerators of discovery via their potential role as biomarkers for research and clinical decision making in cardiovascular disease. Specific barriers relating to biomarker validation, laboratory methods, and improvement of risk models are introduced and discussed. Potential therapeutic impacts in cardiovascular disease are also mentioned with special consideration for cost-saving implications with respect to dietary fish oil as an alternative to resolvin and protectin treatment. Given the high tolerability of fish oil supplements and previously described benefits of omega-3 fatty acid intake in cardiovascular disease, we conclude that resolvins and protectins are set to soon take center stage as future biomarkers and well-tolerated therapies for cardiovascular disease.
Host Cell Interactions Are a Significant Barrier to the Clinical Utility of Peptide Antibiotics (2016)

Despite longstanding promise and many known examples, antimicrobial peptides (AMPs) have failed, thus far, to impact human medicine. On the basis of the physical chemistry and mechanism of action of AMPs, we hypothesized that host cell interactions could contribute to a loss of activity in vivo where host cells are highly concentrated. To test this idea, we characterized AMP activity in the presence of human red blood cells (RBC). Indeed, we show that most of a representative set of natural and synthetic AMPs tested are significantly inhibited by preincubation with host cells and would be effectively inactive at physiological cell density. We studied an example broad-spectrum AMP, ARVA (RRGWALRLVLAY), in a direct, label-free binding assay. We show that weak binding to host cells, coupled with their high concentration, is sufficient to account for a loss of useful activity, for at least some AMPs, because >1 × 10<sup>8</sup> peptides must be bound to each bacterial cell to achieve sterilization. The effect of host cell preincubation on AMP activity is comparable to that of serum protein binding. Feasible changes in host cell binding could lead to AMPs that do not lose activity through interaction with host cells. We suggest that the intentional identification of AMPs that are active in the presence of concentrated host cells can be achieved with a paradigm shift in the way AMPs are discovered.
A Proposed Approach for Character Recognition Using Document Analysis with OCR (2018)

Data entry has been a hectic job since the era of data accumulation started. Apparently, that is why there is a full-fledged career in data entry. Data entry method varies with requirements. Early days of computers relied on punch cards and gradually keyboards and mouse came into picture which we still use. Touchscreens didn't take much time to replace the physical keyboard inputs and now as the result of human intelligence and innovation, the era of the optical input is here. Where the user does not even have to take the pain of thinking about entering data but can simply use an optical reader or scanner to input data. Using the computational power the individual elements like text, images, and special characters can be distinguished. OCR-Optical Character Recognizer does the work. OCR works similar to humans when it comes to character recognition as it maintains a database of characters and compares all the scanned elements with the database which makes it really simple to understand. This paper explains the working of an OCR in its different stages. That study helps in finding the various drawbacks of the conventional system. The paper also tells about how those shortcomings can be eliminated and how a better OCR that is future ready can be achieved.
Dietary flavonoid intake and weight maintenance: three prospective cohorts of 124 086 US men and women followed for up to 24 years (2016)

Higher intake of foods rich in flavonols, flavan-3-ols, anthocyanins, and flavonoid polymers may contribute to weight maintenance in adulthood and may help to refine dietary recommendations for the prevention of obesity and its potential consequences.