gebhart/patrepeval huggingface dataset:
Winter Witness: Will Dyson's Australia At War and Other War Drawings (1986)

Late in August 1916, with 'Fanny Durack' diving from the steeple of the Albert CathedraJI and Pozieres reduced to rubble, Will Dyson applied to join the Australians on the Western Front. This decision to go to France to, as he explained, 'interpret in a series of drawings for national preservation, the sentiments and special Australian characteristics of our Army? was, perhaps, stimulated by the emotional reception given to the Anzacs when they marched in London on 25 April 1916. But Dyson's nationalist feelings -a complex mixture of anxiety and pride - had been deepening since news began to filter back to England of the Gallipoli Campaign, and as the Australian Fifth D1vision prepared to enter the war. It was not until December, however, that Dyson, now a lieutenant, landed in France and began his war drawings. !his was not the
Email Virus Propagation Modeling and Analysis (2003)

Abstract — Email viruses constitute one of the major Internet security problems. In this paper we present an email virus model that accounts for the behaviors of email users, such as email checking frequency and the probability of opening an email attachment. Email viruses spread over a logical network defined by email address books. The topology of email network plays an important role in determining the behavior of an email virus spreading. Our observations suggest that the node degrees in an email network are heavy-tailed distributed and we model it as a power law network. We compare email virus propagation on three topologies: power law, small world and random graph topologies. The impact of the power law topology on the spread of email viruses is mixed: email viruses spread more quickly than on a small world or a random graph topology but immunization defense against viruses is more effective on a power law topology.
A New Class of Unsafe Primes. (2002)

In this paper, a new special-purpose factorization algorithm is presented, which finds a prime factor p of an integer n in polynomial time, if 4p − 1 has the form db 2
Expression and characterization of functionally active fragments of the platelet glycoprotein (GP) Ib-IX complex in mammalian cells. Incorporation of GP Ib alpha into the cell surface membrane. (1993)

The platelet glycoprotein Ib-IX complex (GP Ib-IX) is essential for the initial attachment of platelets to the wall of damaged arteries. In this study, an N-terminal fragment of human GP Ib alpha (residues 1-318), containing the ligand binding sites for von Willebrand factor (vWF) and thrombin, as well as the entire human GP Ib alpha were expressed in Chinese hamster ovary cells. The transfected cells secreted a 48- and a 110-kDa protein, respectively, into the supernatant. Both recombinant proteins were purified by immunoaffinity chromatography. The purified proteins bound soluble vWF in the presence of botrocetin as demonstrated in solid-phase binding assays. The dissociation constant (Kd) for 125I-vWF binding to the recombinant 110-kDa protein was 1.2 +/- 0.2 nM as compared with 1.0 +/- 0.3 nM for vWF binding to purified platelet GP Ib-IX. Both recombinant proteins were also retained on thrombin-Sepharose 4B. The 48-kDa protein contained two N-linked oligosaccharide chains. A 125-kDa protein was identified in the lysate of cells transfected with the coding sequence for the entire GP Ib alpha. Trypsin treatment of this protein generated a 110-kDa fragment, whereas the secreted 110-kDa protein remained unchanged. Post-translational removal of the C-terminal transmembrane domain of recombinant GP Ib alpha might have facilitated the secretion of the soluble glycocalicin-like 110-kDa fragment. In addition, flow cytometry and immunofluorescence microscopy demonstrated that the expression of GP Ib alpha alone is sufficient for its incorporation into the cell surface membrane. These data indicate that two soluble fragments of human GP Ib alpha with binding activity for vWF and thrombin can be expressed in mammalian cells and that the incorporation of GP Ib alpha into the surface membrane does not depend on co-expression with GP Ib beta and/or GP IX.
The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A (2006)

The invasion of tumour cells into brain tissue is a pathologic hallmark of WHO grades II-IV gliomas and contributes significantly to the failure of current therapeutic treatments. Activated microglial cells are abundant in brain tumours and may support tumour invasiveness. We have previously demonstrated that cyclosporin A (CsA) can affect growth of glioma cells in vitro by inhibiting signalling pathways, which are essential for tumour proliferation and invasiveness. In this work, we demonstrate that migration of EGFP-transfected glioblastoma cells in organotypic brain slices was significantly inhibited by treatment with CsA. On average 77% of untreated cells migrated beyond 500 mum, while only 28-33% cells migrated as far in the brain slices treated with CsA (P < 0.001). This inhibitory effect on glioblastoma invasion was lost when glioblastoma cells were injected into microglia-depleted brain slices. Moreover, CsA significantly inhibits intracranial glioma growth in vivo. We demonstrate that microglia-derived factors increase glioma invasiveness in Matrigel assay in vitro and this is associated with activation of the PI-3K/Akt signalling pathway. The invasion promoting effect of microglia is abolished in the presence of CsA. Furthermore, glioma-derived soluble factors induce morphological transformation of microglia and activate MAPK signalling, although production of pro-inflammatory factors was not observed. Our findings that CsA interferes at clinically relevant concentrations with the tumour-promoting role of microglia and impairs invasive growth of glioma cells in vivo may provide a novel therapeutic strategy against gliomas.
Simplified Algorithm to Model Aircraft Acceleration During Takeoff (2008)

*† Aircraft take-off performance, which quantifies the aircraft’s capability of accelerating to become airborne within the runway constraints, is crucial to the safety of the manoeuvre. As a result, scheduled calculations are performed prior to dispatch to ensure that runway lengths are indeed adequate. The same equations, however, cannot readily be used for realtime performance monitoring and a simplified algorithm is thus required. The use of a second order approximation of the velocity profile is proposed. An assessment of the goodness of fit using numerical analysis confirms that, for the operational envelope of typical aircraft, this approximation is sufficiently accurate to warrant use in performance estimation.
A model of how targeted and universal welfare entitlements impact on material, psycho-social and structural determinants of health in older adults (2017)

A growing body of research attests to the impact of welfare regimes on health and health equity. However, the mechanisms that link different kinds of welfare entitlement to health outcomes are less well understood. This study analysed the accounts of 29 older adults in England to delineate how the form of entitlement to welfare and other resources (specifically, whether this was understood as a universal entitlement or as targeted to those in need) impacts on the determinants of health. Mechanisms directly affecting access to material resources (through deterring uptake of benefits) have been well documented, but those that operate through psychosocial and more structural pathways less so, in part because they are more challenging to identify. Entitlement that was understood collectively, or as arising from financial or other contributions to a social body, had positive impacts on wellbeing beyond material gains, including facilitating access to important health determinants: social contact, recognition and integration. Entitlement understood as targeted in terms of individualised concepts of need or vulnerability deterred access to material resources, but also fostered debate about legitimacy, thus contributing to negative impacts on individual wellbeing and the public health through the erosion of social integration. This has important implications for both policy and evaluation. Calls to target welfare benefits at those in most need emphasise direct material pathways to health impact. We suggest a model for considering policy change and evaluation which also takes into account how psychosocial and structural pathways are affected by the nature of entitlement.
Nucleotides. Part XLI. The 2‐dansylethoxycarbonyl ( 2‐{[5‐(dimethylamino)naphthalen‐1‐yl]sulfonyl}ethoxycarbonyl; dnseoc) group for protection of the 5′‐hydroxy function in oligodeoxyribonucleotide synthesis (1994)

Abstract Use of the 2‐dansylethoxycarbonyl (  2‐{[5‐(dimethylamino)naphthalen‐1‐yl]sulfonyl}ethoxycarbonyl; Dnseoc) group as an intermediate 5′‐OH protecting group in oligodeoxyribonucleotide synthesis using the automated phosphoramidite approach is described in a model study to an alternative strategy in RNA synthesis.
Directed Chlorination of Fluorinated Aliphatic Ethers<sup>1</sup> (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDirected Chlorination of Fluorinated Aliphatic Ethers1J. D. Park, D. M. Griffin, and J. R. LacherCite this: J. Am. Chem. Soc. 1952, 74, 9, 2292–2294Publication Date (Print):May 1, 1952Publication History Published online1 May 2002Published inissue 1 May 1952https://pubs.acs.org/doi/10.1021/ja01129a036https://doi.org/10.1021/ja01129a036research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Transferring Rich Deep Features for Facial Beauty Prediction (2018)

Feature extraction plays a significant part in computer vision tasks. In this paper, we propose a method which transfers rich deep features from a pretrained model on face verification task and feeds the features into Bayesian ridge regression algorithm for facial beauty prediction. We leverage the deep neural networks that extracts more abstract features from stacked layers. Through simple but effective feature fusion strategy, our method achieves improved or comparable performance on SCUT-FBP dataset and ECCV HotOrNot dataset. Our experiments demonstrate the effectiveness of the proposed method and clarify the inner interpretability of facial beauty perception.
Antenna effects on the capacity of MIMO communications systems in Rayleigh channels (2005)

Multiple input and multiple output (MIMO) is a new technology that promises to significantly increase the capacity of wireless communication systems. MIMO technology increases capacity by exploiting the multipath channel. Unfortunately results presented in the literature (Gesbert et al., Smith et al.) neglect antenna effects. This paper investigates the effect that parameters such as number, spacing, coupling and far field antenna patterns of antennas have on the capacity of MIMO systems in Rayleigh channels.
El debate comienza en la clinica. (2007)

Los autores, un analista y su supervisada, intentan, a través del análisis de un material clínico, realizar un trabajo de investigación sobre algunos conceptos de la práctica psicoanalítica, entendiendo que el proceso analítico se da en un espacio privilegiado para la construcción del sujeto psíquico así como para el enriquecimiento e intercambio intersubjetivos entre ambos integrantes de la dupla. Con el intento de promover el debate, nos abocamos a pensar sobre tres aspectos que nos resultan de fundamental importancia para la praxis: 1) la interrogante sobre ¿qué es lo que ocurre en la mente del terapeuta desde la escucha a la interpretación?, específicamente dirigido al problema de los aspectos teóricos implícitos. 2) El tema de la interpretación, su testeo y validación en el curso de la sesión y aún en la marcha del proceso, tanto en lo que atañe al analizado como al escrutinio de la contratransferencia del analista. 3) La consideración del aspecto terapéutico del ¿enactment¿ tomando en cuenta la producción psicoanalítica de los últimos años que ha mostrado la relevancia que para el proceso de cambio adquieren las diferentes formas en que paciente y analista establecen su comunicación. A través de lo que consideramos una investigación conceptual, y su debate en un Congreso sobre la subjetivación, es como entendemos que se van reformulando muchas propuestas freudianas lo que permite un reconocimiento de la vigencia viva del psicoanálisis actual.
Controling simulation study on two-wheeled self-balancing electrical motorcycle based on ADAMS and MATLAB (2011)

On the basis of mathematical model of two-wheeled self-balancing electrical motorcycle,we use virtual prototype technology in this paper to build mechanical system model and controling system model of two-wheeled self-balancing electrical motorcycle seperately in ADAMS and MATLAB,and then connect the both by ADAMS/Control interface module for realising interactive simulation of control under software system environment. Practice proves co-simulation of dynamic system and control system have promoted efficiency and reliability of two-wheeled self-balancing electrical motorcycle designing,and it is a precise and high efficient optimal design method.
Ka-Band 3-D-Printed Wideband Groove Gap Waveguide Orthomode Transducer (2019)

An orthomode transducer (OMT) that falls into the twofold symmetry category is designed at the Ka-band with 33.33% bandwidth. Groove gap waveguide (GGWG) technology is adapted to implement the design due to its suitability for millimeter-wave (mm-wave) frequencies as electrical contacts between different parts are not necessary. Moreover, two transitions are deployed to broaden the operating bandwidth. The first transition is GGWG to WR-28 standard waveguide, which also acts as a power combiner. The second transition is placed between two layers of GGWGs. This new OMT consists of two main sections, the OMT core section, and the assembly section of different parts. Each section is investigated and simulated separately; then the whole structure is simulated to validate the performance. A prototype is built using 3-D-printing technology with copper-electroplated surfaces. A back-to-back measurements technique indicated matching and isolation level better than 12.5 and 25 dB, respectively, for both polarizations over the entire band. Nevertheless, the insertion loss has an acceptable level over such bands.
Human Cytomegalovirus: Challenges Opportunities and New Drug Development (1999)

In the age of highly active antiretroviral therapy, the incidence of human cytomegalovirus (HCMV) retinitis in AIDS patients has decreased substantially. However, this change does not indicate that HCMV disease in AIDS patients and other immunocompromised patients has abated and is no longer a concern. On the contrary, HCMV disease in graft recipients, newborns, and even in AIDS patients still accounts for considerable morbidity, and drug resistance to the anti-HCMV compounds is a major problem. Furthermore, HCMV may have a role in metabolic diseases, such as atherosclerosis. Fortunately there are novel and potentially very effective new compounds undergoing pre-clinical and clinical evaluation. These developments point the way toward new therapies and also to a clearer understanding of the biology of HCMV replication, infection and disease.
Improvement of Corrosion Detection Using Vision System for Pipeline Inspection (2015)

Nowadays, the utilization of cameras as an inspection tool has been increasing. The flexibility functions of camera fits to get different kind of information. This research is focusing on developing a robust visual inspection system for corrosion detection that is able to detect corrosion in any environment, and the corrosion detection will be using visual data as primary tools. A review on current pipeline inspection would give a brief detail on the improvement of the proposed inspection system. Furthermore, the inadequacies of the proposed visual corrosion detection are identified and discussed from the reviewing process on existing researches and analysis on preliminary data obtained. It is expected that the output of the proposed system will be a new method of corrosion detection and pioneer for the inspection system on robust environment.
Synthesis of novel 1‐aryl[1]benzoxepino[5,4‐<i>c</i>]pyrazole and [1]benzoxepino[5,4‐<i>d</i>]pyrimidine derivatives (1993)

Abstract Several 1‐aryl[1]benzoxepinopyrazoles were prepared by reaction of 4‐hydroxymethylene[1]benzoxepin‐ones with appropriate phenylhydrazine hydrochlorides. The direct condensation of hydroxymethylenebenz‐oxepinones with variously substituted amidines failed to give benzoxepinopyrimidines. These compounds were obtained via the key intermediates morpholine enaminobenzoxepinones.
Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses (2004)

Most individuals exposed to hepatitis C virus (HCV) become chronically infected and are predisposed to liver disease. The mechanisms underlying viral persistence and disease progression are unknown. A role for the HCV NS5A protein in viral replication and interferon resistance has been demonstrated. To identify mechanisms affected by NS5A, we analyzed the gene expression of Huh7 cells expressing NS5A and control cells using oligonucleotide microarrays. A set of 103 genes (43 up-regulated, 60 down-regulated) whose expression was modified by at least twofold was selected. These included genes involved in cell adhesion and motility, calcium homeostasis, lipid transport and metabolism, and genes regulating immune responses. The finding of modulated expression of genes related to the TGF-beta superfamily and liver fibrosis was observed. Interestingly, both the tumor necrosis factor and lymphotoxin beta receptors were down-regulated by NS5A. Similar data were obtained following expression of four NS5A mutants obtained from patients who were not responsive or were sensitive to interferon therapy. Through computational analysis, we determined that 39 of the 43 genes up-regulated by NS5A contained one or more nuclear factor kappaB (NF-kappaB) binding sites within their promoter region. Using the Gibbs sampling method, we also detected enrichment of NF-kappaB consensus binding sites in the upstream regions of the 43 coexpressed genes. Activation of NF-kappaB by NS5A was subsequently demonstrated in luciferase reporter assays. Adenovirus-mediated expression of IkappaBalpha reverted NS5A mediated up-regulation of gene expression. In conclusion, this study suggests a role of NS5A and NF-kappaB in HCV pathogenesis and related liver disease. Supplementary material for this article can be found on the HEPATOLOGY website (http://interscience.wiley.com/jpages/0270-9139/suppmat/index.html).
A Review of Studies of the Hamilton Depression Rating Scale in Healthy Controls (2004)

The Hamilton Rating Scale for Depression (HRSD) is the most commonly used symptom severity scale to evaluate the efficacy of antidepressant treatment. On the basis of an expert consensus panel, an HRSD score of < or = 7 was recommended as a cutoff to define remission. Since that recommendation, little empirical work has been conducted to confirm the validity of this threshold. One approach toward determining a cutoff score for defining remission is to establish the range of values for healthy controls. We therefore conducted a literature review of studies of the HRSD in healthy controls to determine the normal range of values. Studies of the HRSD in healthy control groups were identified in two ways. First, a MEDLINE search for the years 1966 to 2002 was conducted using the key words Hamilton, depression, and controls, and articles were reviewed. Second, the 69 studies included in two review articles written by the authors were examined. We identified 27 studies that included data on the HRSD for 1014 healthy controls. Across all studies, the weighted mean (SD) HRSD score, adjusting for sample size, was 3.2 (3.2; 95% CI, 3.0 to 3.4). HRSD scores were similar in geriatric and nongeriatric samples, and in men and women. Because HRSD scores in healthy controls are more likely to follow a skewed than a normal distribution, based on a mean of 3.2 and a SD of 3.2, at least 84% of healthy controls scored 7 or less on the HRSD, and 97.5% scored 10 or less. Thus, these results can be taken as support for the recommended cutoff of 7 on the HRSD to define remission. The results can also be used for normative comparisons in which posttreatment group mean scores are compared with mean scores from normative samples.
Tumor Angiogenesis: Iris Neovascularization at a Distance From Experimental Intraocular Tumors2 (1973)

Journal Article Tumor Angiogenesis: Iris Neovascularization at a Distance From Experimental Intraocular Tumors Get access Michael A. Gimbrone, Jr., M.D., Michael A. Gimbrone, Jr., M.D. Department of Surgery, Children's Hospital Medical Center; Harvard Pathology Unit, Mallory Institute of Pathology; and Departments of Surgery and Pathology, Harvard Medical School, Boston, Massachusetts 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar Stephen B. Leapman, M.D., Stephen B. Leapman, M.D. Department of Surgery, Children's Hospital Medical Center; Harvard Pathology Unit, Mallory Institute of Pathology; and Departments of Surgery and Pathology, Harvard Medical School, Boston, Massachusetts 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar Ramzi S. Cotran, M.D., Ramzi S. Cotran, M.D. Department of Surgery, Children's Hospital Medical Center; Harvard Pathology Unit, Mallory Institute of Pathology; and Departments of Surgery and Pathology, Harvard Medical School, Boston, Massachusetts 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar Judah Folkman, M.D. Judah Folkman, M.D. 5 Department of Surgery, Children's Hospital Medical Center; Harvard Pathology Unit, Mallory Institute of Pathology; and Departments of Surgery and Pathology, Harvard Medical School, Boston, Massachusetts 02115 5Address reprint requests to: Dr. Judah Folkman, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 50, Issue 1, January 1973, Pages 219–228, https://doi.org/10.1093/jnci/50.1.219 Published: 01 January 1973 Article history Received: 25 July 1972 Accepted: 20 September 1972 Published: 01 January 1973