gebhart/patrepeval huggingface dataset:
Dynamic reconfiguration of persistent computing systems based on soft system bus (2012)

Anytime reconfigurability of computing systems is indispensable to persistent computing as well as ubiquitous/pervasive/cloud computing. To require that a computing system function continuously anytime entails that the computing system has to be reconfigured dynamically during its continuous running. This paper shows our approach to dynamic reconfiguration of persistent computing systems constructed based on soft system buses. The paper presents a requirement analysis for the dynamic reconfiguration of persistent computing systems based on soft system buses, proposes an architecture of persistent computing systems based on soft system buses that satisfied the requirements, and presents some implementation issues.
InAsSb-based<i>nBn</i>photodetectors: lattice mismatched growth on GaAs and low-frequency noise performance (2015)

An InAsSb nBn detector structure was grown on both GaAs and native GaSb substrates. Temperature dependent dark current, spectral response, specific detectivity (D*) and noise spectral density measurements were then carried out. Shot-noise-limited D*figures of 1.2 10 Jones × 10 and 3.0 10 Jones × 10 were calculated (based upon the sum of dark current and background photocurrent) for the sample grown on GaAs and the sample grown on GaSb, respectively, at 200 K. Noise spectral density measurements revealed knee frequencies of between 124–337 Hz and ∼8 Hz, respectively. Significantly, these devices could support focal plane arrays capable of operating under thermoelectric cooling.
A Play-Based Evaluation of a Deepwater Sabah Exploration Area: Prospect Maturation and Implications for Remaining Prospectivity (2018)

Abstract This study presents a play-based evaluation of the southern part of the deepwater NW Sabah fold-thrust belt, a key exploration area in Malaysia. The key objective was adding value to the existing database through an integrated approach. This goal was achieved by analysing four critical geological risk elements: reservoir presence, structural evolution, top seal integrity, and timing of hydrocarbon charge and migration, to identify prospective areas for future exploration by integrating all available geological, geophysical and geochemical information into a consistent petroleum system framework. Using the basin-play-prospect maturation workflow, data spanning the geophysical domain (with inputs such as seismic evaluation, structural mapping and attribute analysis) to the geological realm (such as well correlations, fairway mapping, sedimentological studies, biostratigraphic investigations and source rock maturation modelling), are combined with structural kinematic evolution to generate detailed play-based element maps. The application of the tried and tested play-based evaluation methodology from basin evaluation through to prospect maturation has been carried out. This has led to a comprehensive play element analysis yielding a composite risk segment map within a consistent petroleum system framework. In addition, the study has provided sensible explanations for dry hole analysis, an important reality check, but most importantly it has generated a fresh insight into the overall prospectivity of the study area. This enhanced multi-discipline analysis is beneficial for reducing exploration risk for future expenditure in a time of depressed oil prices that calls for a more innovative approach for deepwater exploration. In summary, integration of available data and the application of new in-house ideas and solid geoscientific knowledge has added value through the generation of increased prospectivity, however for further ground-truthing the real litmus test has to come from future drilling.
The Evolution of Neutron Straw Detector Applications in Homeland Security (2013)

The dwindling supply of <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> He has necessitated the adoption of new technologies for detection of neutrons especially in Homeland Security (HS), where detectors require large volumes of the precious gas. The boron-coated straw (BCS) technology consists of very thin-walled metal tubes equipped with a highly robust coating of <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</sup> B <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> C on the inner wall. The coating, applied with Physical Vapor Deposition (PVD), is atomically bound to the metal substrate, and it is able to resist delamination over a temperature range from -200 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C to 1000 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C. Accelerated lifetime testing of sealed straw detectors over extreme temperature ranges (-70 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C to +125 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> C) have recently demonstrated a 99% expected lifetime of 30 years. At the same time, the coating purity is high, with a <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</sup> B content approaching 77%. Straws stacked 5 deep in a dense array have demonstrated an efficiency of > 70% when evaluated in a cold neutron beam. A number of field worthy HS detectors have been developed over the past 2 years based on the BCS. Examples are presented, including neutron modules for Radiation Portal Monitors (RPM), a vehicle mounted modular detector with an intrinsic efficiency of 30% for unmoderated <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">252</sup> Cf neutrons, and handheld detectors. All of these systems have been government tested. The <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</sup> B <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> C coated straw offers a highly versatile, robust and low cost technology meeting multiple needs in homeland and international security.
Design of low-voltage active mixer for direct conversion receivers (2002)

Evolution and design trade-offs of a high performance, low-voltage downconversion mixer for wireless direct conversion receivers (DCR) are studied in this paper. As a first step, a mixer with active loads and adjustable conversion gain is presented. Then a different mixer topology that provides high conversion gain without deteriorating the linearity and noise performance is discussed. Finally, this topology is found to be well suitable for very low-voltage applications and thus its design and voltage scalability is depicted. The presented mixers are designed using a 0.35-/spl mu/m BiCMOS process and characterized at 2 GHz frequency.
Intermediate filament assembly and stability : Effect and implications of the removal of head and tail domains of vimentin by the human immunodeficiency virus type 1 protease (1990)

The intermediate filament subunit protein vimentin is efficiently cleaved in vitro by purified human immunodeficiency virus type 1 protease. Immunological data confirm that identical sites are cleaved when vimentin is polymerized into filaments or occurs as protofilaments. The primary cleavage gives rise to a molecule lacking most of the tail domain and which not only remains in preformed filaments, but is also capable of polymerizing into essentially normal 10 nm filaments. However, these filaments show a propensity to form large lateral aggregates. The three secondary cleavage products of vimentin additionally lack portions of the head domain, are almost quantitatively (greater than 95%) released from preformed filaments and are not capable of forming filaments de novo. These results extend the limits of the head and tail domains of vimentin that play a role in filament formation and stability.
DIGESTIBILITY, NITROGEN RETENTION AND CALORIC VALUE OF RAPESEED AND SOYBEAN MEALS WHEN FED AT TWO DIETARY LEVELS TO CALVES (1970)

Pre-pressed, solvent-extracted rapeseed and solvent-extracted soybean meals were fed with a basal diet to Holstein bull calves at levels to support maintenance or growth. Maintenance requirement was based on digestible energy (DE) = 145 W 0.75 (kg). Growth rates of 0.55 and 0.75 kg per day were supported by intakes of 1.66 and 1.92 × maintenance for rape-basal and soy-basal diets. The digestibility of proximate components and energy were determined by the "difference" procedure. The derived crude protein digestion coefficients of rapeseed and soybean meals were 89 and 93%, resulting in digestible protein contents of 35 and 47%, respectively. The gross energy digestion coefficient was lower (P < 0.01) at the maintenance level of intake than at the level for growth, for both mixed rations (81, 89 for rapeseed meal and 78, 88 for soybean meal). The mean caloric values of rapeseed and soybean meals derived by difference were 3213 and 2926 kcal DE/kg dry matter, respectively. It was concluded that rapeseed meal is lower in digestible protein content but equal to or greater in DE value than soybean meal.
Simulation case studies in the print/finish industry (1998)

Process simulation is a powerful analysis tool used in many industries. It allows companies to be proactive in determining what strategies will be successful. For this reason, manufacturing companies have incorporated simulation models into their decision making processes for years. However, many industries have not taken full advantage of process simulation. One industry facing problems similar to manufacturing is the print/finish industry. Because of similarities to the manufacturing world, we have been able to use simulation to help companies in the print/finish industry address the problem of how to get more volume through the system in a shorter amount of time. The paper discusses two particular cases in which simulation was used to solve these problems under differing circumstances.
Review of Microneedle based Transdermal Drug Delivery Systems (2019)

Transdermal drug delivery (TDD) provides an attractive and alternative drug delivery when compared to oral and other drug delivery as the former route offers several advantages like avoiding pre-systemic first pass metabolism of administered drugs, patient compliance, and avoiding gastric irritation. However, stratum corneum (SC), the upper most layer of skin, limits the permeation of number of drugs because of its barrier property. To breach or bypass this barrier, two approaches namely: chemical and physical are generally used. Physical approaches seem to be better as it does not involve the use of chemicals in the formulations, which could interact, with other component of formulations and more importantly may cause reversible damage to the skin. Microneedle technique is one of the most advanced physical techniques, which can easily by-pass, the SC and allow the drug to reach viable epidermis directly. The needles used in microneedle techniques are in hundreds of micron length range and when applied on skin generally produce little or no pain. The objective of this review is mainly focused on types of microneedles, various materials and fabrication techniques used in the preparation of microneedles. Furthermore, various techniques used in the application of microneedles and mechanism of action are described. In addition, this review also describes commercial products, patents on microneedle technology and recent works carried out on microneedles research and safety aspects of microneedles.
Inter-domain Authentication for Seamless Roaming in Heterogeneous Wireless Networks (2008)

The inter-operation among heterogeneous wireless networks is crucial to support ubiquitous mobility and seamless roaming. Handoffs across wireless networks in separate administrative domains should ensure uninterrupted service and authenticity of the entities involved. However, the re-authentication of a mobile node (MN) during a handoff across administrative domains typically involves several round trips to the home domain which produce long latencies. A new authentication protocol based on the use of proof tokens is presented in this paper which allows a MN to authenticate in a foreign domain without requiring communication with its home domain. Moreover, the foreign domain is only required to have a trust relationship with any one of MN's previously visited domains, and not necessarily with the home domain. Our objective is to provide an improved authentication approach for ubiquitous mobility and seamless roaming that does not compromise the security of the handoff process while providing low delays.
Positive and negative DNA sequence elements are required to establish the pattern of <i>Pax3</i> expression (1997)

The transcription start site and DNA sequence elements required for the induction of Pax3 expression in differentiating P19 embryonal carcinoma cells have been localized. These elements consist of a promoter and additional elements located within 1.6 kbp 5' to the transcription start site. Sequence elements within this 1.6 kbp region are also sufficient to mediate the induction and dorsal restriction of Pax3 in the neural tube and somites of transgenic mice throughout the hindbrain and trunk. Additional elements required for expression anterior to the hindbrain and in migrating myoblasts are located within 14 kbp 5' to the transcription start site. This region also contains element(s) that repress Pax3 expression in the ventral body wall mesoderm of the tail bud.
Towards a Canadian Model of Integrated Healthcare (2000)

CANADA DOES NOT HAVE INTEGRATED HEALTHCARE.Canada has a series of disconnected parts, a hodge-podge patchwork, healthcare industry comprising hospitals, doctors' offices, group practices, community agencies, private sector organizations, public health departments and so on.Each Canadian province is experimenting with different types of organizational structures and processes with the intent of improving the coordination of services, facilitating better collaboration among providers and providing better healthcare to the population.However, regional health authorities and their variants in Canada do not possess most of the basic characteristics of integrated healthcare such as physician integration and a rostered population (Hospital Management Research Unit 1996,1997).In contrast, most developed countries are currently emphasizing integration of the components of healthcare as a 13
Constant-frequency resonant inverter for AC-bus distribution system (2005)

A new constant-frequency DC-AC resonant inverter that employs a coupled inductor to achieve ZVS in an entire load and input voltage range with a reduced circulating current is described. The proposed technique is suitable for AC-bus distribution power systems in data-processing equipment. The performance of the proposed approach was evaluated on a 230 W inverter that delivers 1-MHz, 27-V/sub RMS/ AC output voltage from a 320 V-400 V DC input.
Carbon reduction in GaAs films grown by laser-assisted metalorganic molecular beam epitaxy (1989)

Secondary-ion mass spectroscopy and cathodoluminescence (CL) studies were carried out on GaAs films grown by Ar+ laser-assisted metalorganic molecular beam epitaxy. The Ar+ laser irradiation leads to the formation of a 400-μm-diam spot. In the growth temperature range 425–500 °C, the carbon concentration within the spot is maintained at 1017 cm−3, while that in the area not irradiated by the laser increases from 1017 to 1019 cm−3. The process of decomposition of the triethylgallium molecules and the mechanism by which the carbon concentration is maintained by the laser irradiation are discussed in detail. Low-temperature CL spectra revealed that the CL signal intensity in the selectively grown spot was some ten times greater than that in the area not irradiated by the laser.
Magnetic Particle Imaging meets Computed Tomography: first simultaneous imaging (2019)

Magnetic Particle Imaging (MPI) is a promising new tomographic modality for fast as well as three-dimensional visualization of magnetic material. For anatomical or structural information an additional imaging modality such as computed tomography (CT) is required. In this paper, the first hybrid MPI-CT scanner for multimodal imaging providing simultaneous data acquisition is presented.
Cell-Penetrating Penta-Peptides (CPP5s): Measurement of Cell Entry and Protein-Transduction Activity (2010)

Previously, we developed cell-penetrating penta-peptides (CPP5s). In the present study, VPTLK and KLPVM, two representative CPP5s, were used to characterize the cell-penetration and protein-transduction activities of these small molecules. Various inhibitors of endocytosis and pinocytosis (chlorpromazine, cytochalasin D, Filipin III, amiloride, methyl-β-cyclodextrin, and nocodazole) were tested. Only cytochalasin D showed suppression of CPP5 entry, though the effect was partial. In addition, CPP5s were able to enter a proteoglycan-deficient CHO cell line. These results suggest that pinocytosis and endocytosis may play only a minor role in the cell entry of CPP5s. By mass spectrometry, we determined that the intracellular concentration of VPTLK ranged from 20 nM to 6.0 μM when the cells were cultured in medium containing 1 μM - 1.6 mM VPTLK. To determine the protein-transduction activity of CPP5s, the Tex-LoxP EG cell line, which has a Cre-inducible green fluorescent protein (GFP) gene, was used. VPTLK and KLPVM were added to the N-terminus of Cre, and these fusion proteins were added to the culture medium of Tex-LoxP EG cells. Both VPTLK-Cre and KLPVM-Cre were able to turn on GFP expression in these cells, suggesting that CPP5s have protein-transduction activity. Since CPP5s have very low cytotoxic activity, even at a concentration of 1.6 mM in the medium, CPP5s could be utilized as a new tool for drug delivery into cells.
Feature-Based Indoor Navigation Using Augmented Reality (2013)

We present a prototype for indoor navigation using Augmented Reality that uses interior features to determine the user's location and provide navigation instructions. We test our prototype in a simulated physical shopping mall environment and find that AR-based navigation can provide usability advantages in indoor locations, particularly where targets are located on different floors. We conclude by recommending further work in presenting interior navigation instructions using AR.
Phase I study of epidermal growth factor receptor (EGFR) inhibitor, erlotinib, and vascular endothelial growth factor monoclonal antibody, bevacizumab, in recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN) (2004)

5539 Background: Studies of EGFR inhibitors in SCCHN have demonstrated reproducible activity. Preclinical studies have implicated angiogenesis as a mechanism of resistance to these agents. Furthermore, angiogenesis has been linked with tumor progression and worse outcome in SCCHN. This phase I multi-institutional trial was undertaken to assess the feasibility and toxicity of adding bevacizumab, an anti-VEGF monoclonal antibody to erlotinib, an EGFR tyrosine kinase inhibitor. Methods: Eligible patients were required to have performance status 2 or better, measurable disease, intact organ function, no more than one prior therapy for recurrent/metastatic disease, and no prior EGFR or VEGF based therapy. Escalating doses of bevacizumab (5, 10, and 15 mg/kg IV q3 weeks) were administered with a fixed dose of erlotinib (150 mg PO QD) to consecutive patient cohorts to establish a phase II dose. Plasma VEGF and serum TGF-alpha levels were drawn prior to therapy, after 2 weeks, and after 8 weeks of therapy. Results: 10 patients have been enrolled with 4, 3, and 3 patients in each cohort. Grade 3 toxicity consisted of diarrhea (1 patient), skin rash (1 patient), lymphopenia (1 patient). One patient experienced grade 4 hemorrhage from a tongue tumor after 6 treatment cycles that was felt to be therapy related. Common grade 1/2 toxicities observed included dermatologic (70%), fatigue (70%), and diarrhea (50%). Dose limiting toxicity, as defined by the protocol, was not observed at any dose level. Of 9 patients evaluated after 2 cycles, we have observed 1 PR, 7 SD, and 1 PD. 6 patients have had stable disease for greater than 12 weeks. Conclusions: Administration of bevacizumab 15mg/kg q3 weeks with erlotinib 150mg QD is feasible and well tolerated in recurrent/metastatic SCCHN. Assessment of regimen efficacy is underway in the phase II segment of this trial. Supported by NCI grant # N01-CM-17102. No significant financial relationships to disclose.
Determination of Traces of Water in Hydrocarbons. A Calcium Carbide-Gas Liquid Chromatography Method. (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Traces of Water in Hydrocarbons. A Calcium Carbide-Gas Liquid Chromatography Method.H. S. Knight and F. T. WeissCite this: Anal. Chem. 1962, 34, 7, 749–751Publication Date (Print):June 1, 1962Publication History Published online1 May 2002Published inissue 1 June 1962https://pubs.acs.org/doi/10.1021/ac60187a010https://doi.org/10.1021/ac60187a010research-articleACS PublicationsRequest reuse permissionsArticle Views238Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Amino-substituted p-benzoquinones (1986)

Based on the observation of outstanding antineoplastic activity of a number of amino-substituted anthraquinones, thioxanthones, and N-(aminoethyl)-substituted naphthalimides, four types of amino-substituted p-benzoquinones were designed, synthesized, and their biological activity evaluated. Although none of these compounds exhibited inhibitory activity against P388 leukemia, 2,5-bis[[4-[(dimethylamino)methyl]phenyl]amino]-3,6-dibromo-1,4- benzoquinone and the corresponding dichloro compound demonstrated good inhibitory activity against the proliferating human colon adenocarcinoma in vitro. The dichloro compound was also found to be active against the leukemia L1210 screening in vitro. 2,5-Bis[[2-(dimethylamino)ethyl]amino]-1,4-benzoquinone possessed inhibitory activity against Neisseria catarrhali.
COMPLEX FORMATION OF CYCLODEXTRINS IN ALCOHOL SOLUTIONS (1984)

Abstract β-Cyclodextrin(β-CD) was found to form inclusion complexes in ethylene glycol, diethylene glycol, triethylene glycol, 2-methoxyethanol, 2-ethoxyethanol, methanol, and glycerine solutions. γ-CD also formed complexes in ethylene glycol solution. The binding of ferrocene by β-CD is stronger in ethylene glycol than in dimethyl sulfoxide and dimethyl formamide.
Time-domain Reconstruction Methods for Ultrasonic Array Imaging : A Statistical Approach (2004)

This thesis is concerned with reconstruction techniques for ultrasonic array imaging based on a statistical approach. The reconstruction problem is posed as the estimation of an image consisting of ...