gebhart/patrepeval huggingface dataset:
Gluconic Acid Production Effect of Pressure, Air flow and Agitation on Gluconic Acid Production by Submerged Mold Growths (1937)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGluconic Acid Production Effect of Pressure, Air flow and Agitation on Gluconic Acid Production by Submerged Mold GrowthsP. A. Wells, A. J. Moyer, J. J. Stubbs, H. T. Herrick, and O. E. MayCite this: Ind. Eng. Chem. 1937, 29, 6, 653–656Publication Date (Print):June 1, 1937Publication History Published online1 May 2002Published inissue 1 June 1937https://pubs.acs.org/doi/10.1021/ie50330a012https://doi.org/10.1021/ie50330a012research-articleACS PublicationsRequest reuse permissionsArticle Views120Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Biosynthesis of the subunits of factor VIIIR by bovine aortic endothelial cells. (1983)

The biosynthesis of the subunit of factor VIIIR was studied in bovine aortic endothelial cells by the techniques of immunoprecipitation and NaDodSO4/polyacrylamide gel electrophoresis. It was determined that the subunit is first produced as a Mr 240,000 glycoprotein precursor, which appears to undergo proteolytic cleavage at or about the time of secretion into the medium with a resultant change in apparent Mr to 225,000, the size of the mature subunit found in plasma. The Mr 240,000 species was detected within 10 min of the start of labeling of cells, but factor VIIIR was not detected in the culture medium until approximately equal to 50 min. Treatment of the cells with tunicamycin resulted in a decrease in the apparent Mr of both species but did not grossly inhibit processing of precursor to product or the secretion of the latter. Thus, much or all N-linked glycosylation of factor VIIIR is not essential for these steps. Accumulation of factor VIIIR in the medium continued over a 24-hr period of cell labeling with [35S]-methionine, without significant net intracellular accumulation of the precursor, suggesting that a large storage pool of factor VIIIR is not present in endothelial cells under these conditions.
Antiangiogenesis Is Produced by Nontoxic Doses of Vinblastine (1999)

The effects of vinblastine (VBL) on endothelial cell functions involved in angiogenesis, namely proliferation, chemotaxis, spreading on fibronectin (FN), secretion of matrix-metalloproteinase-2 (MMP-2) and MMP-9, and morphogenesis on Matrigel were tested in vitro, whereas its effects on angiogenesis were studied in vivo by using the chick embryo chorioallantoic membrane (CAM) model. In vitro, at noncytotoxic doses (0.1, 0.25, 0. 5, 0.75, and 1 pmol/L), VBL impacted all these functions, except secretion of MMPs, in a dose-dependent fashion. By contrast, proliferation of other primary cells such as fibroblasts and lymphoid tumor cells was not impacted. In vivo, VBL at 0.5, 0.75, and 1 pmol/L again displayed a dose-dependent antiangiogenic activity. Lack of cytotoxicity in vitro and in vivo was shown both morphologically, and also because the antiangiogenic effects were rapidly abolished when VBL was removed. Apoptosis was not induced. At the ultrastructural level, impairment of cell functions in vitro was associated with thin disturbance of the cytoskeleton, in the form of slight depolymerization and accumulation of microfilaments, which was equally reversible. Results suggest that VBL has an antiangiogenic component at very low, noncytotoxic doses, and that antiangiogenesis by VBL could be used to treat a wide spectrum of angiogenesis-dependent diseases, including certain chronic inflammatory diseases, Kaposi's sarcoma, and cancer.
Leigh Hunt And Anna Maria Dashwood: A Shelleyan Romance (1988)

d re sp e c tin g L eigh H u n t's re la tio n s h ip w ith A n n a M aria D a sh
A proposed research framework for distributed group support systems (2002)

Distributed group support system (DGSS) is technology that can help groups to overcome some of the problems associated with being in different places and different time zones. The purpose of this paper is to propose a framework for DGSS research that will encompass the major issues involved in the application of DGSS. The issues, compiled from a literature review and a small scale survey of practitioners, include topics, such as security of information, identification of approved members, and the role of a facilitator. The changing structure of organizations due to downsizing and globalization, is being assisted by the increased access to communication media, such as videoconferencing, fax, and high speed data networks. As the changes take place there is a need to define the use of the technology and to define the structure of the distributed group.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Elevated Fasting Total Plasma Homocysteine Levels and Cardiovascular Disease Outcomes in Maintenance Dialysis Patients (1997)

There is an excess prevalence of hyperhomocysteinemia in dialysis-dependent end-stage renal disease (ESRD) patients. Cross-sectional studies of the relationship between elevated total homocysteine (tHcy) levels and prevalent cardiovascular disease (CVD) in this patient population suffer from severe methodologic limitations. No prospective investigations examining the association between tHcy levels and the subsequent development of arteriosclerotic CVD outcomes among maintenance dialysis patients have been reported. To assess whether elevated plasma tHcy is an independent risk factor for incident CVD in dialysis-dependent ESRD patients, we studied 73 maintenance peritoneal dialysis or hemodialysis patients who received a baseline examination between March and December 1994, with follow-up through April 1, 1996. We determined the incidence of nonfatal and fatal CVD events, which included all validated coronary heart disease, cerebrovascular disease, and abdominal aortic/lower-extremity arterial disease outcomes. After a median follow-up of 17.0 months, 16 individuals experienced at least one arteriosclerotic CVD event. Cox proportional-hazards regression analyses, unadjusted and individually adjusted for creatinine, albumin, and total cholesterol levels, total/HDL cholesterol ratio, dialysis adequacy/residual renal function, baseline CVD, and the established CVD risk factors (ie, age, sex, smoking, hypertension, diabetes/glucose intolerance, and dyslipidemia) revealed that tHcy levels in the upper quartile (> or = 27.0 mumol/L) versus the lower three quartiles (< 27.0 mumol/L) were associated with relative risk estimates (hazards ratios, with 95% confidence intervals for the occurrence of (pooled) nonfatal and fatal CVD ranging from 3.0 to 4.4; 95% confidence intervals (1.1-8.1) to (1.6-12.2). We conclude that the markedly elevated fasting tHcy levels found in dialysis-dependent ESRD patients may contribute independently to their excess incidence of fatal and nonfatal CVD outcomes.
Optical, thermal, and electrical monitoring of radio-frequency tissue modification (2010)

Radio-frequency (rf) tissue fusion involves the sealing of tissue between two electrodes delivering rf currents. Applications include small bowel fusion following anastomosis. The mechanism of adhesion is poorly understood, but one hypothesis is that rf modification is correlated to thermal damage and dehydration. A multimodal monitoring system capable of acquiring tissue temperature, electrical impedance, and optical transmittance at 1325-nm wavelength during rf delivery by a modified Ligasure fusion tool is presented. Measurements carried out on single layers of ex vivo porcine small bowel tissue heated at approximately 500-kHz frequency are correlated with observation of water evaporation and histological studies on full seals. It is shown that the induced current generates a rapid quasilinear rise of temperature until the boiling point of water, that changes in tissue transmittance occur before impedance control is possible, and that a decrease in transmission occurs at typical denaturation temperatures. Experimental results are compared with a biophysical model for tissue temperature and a rate equation model for thermal damage.
Class and Encapsulation (2012)

This chapter indicates that class and object are the central concepts of object-oriented programming (OOP). One can only work with a specific instance of a class, which is called an object. An object can include many variables to hold data and many functions to work with them. Therefore, a class can be a much more powerful data type and an object can be a much more versatile variable. That a class and objects of its type hold all the data and functionality needed to work with that data is what is meant by encapsulation. A key feature of class, which makes encapsulation possible, is that one can control what parts of a program the member variables and functions of class can be accessed.
Electrolysis of ammonium carbamate: A voltammetric and X-ray photoelectron spectroscopic investigation into the modification of carbon electrodes (2007)

Uchiyama et al. report that a glassy C (GC) electrode modified with surface amino groups via the electrochem. oxidn. of ammonium carbamate can react with catechol in a 1,4-Michael addn. through the surface amino groups. This was deduced from XPS data and the observation of a new reversible couple at less pos. potentials than the catechol redox couple, which was attributed to a quinone-imine-like adduct. Identical voltammetry is obsd. at an unmodified GC electrode that was oxidatively pre-treated in an identical fashion to that reported by Uchiyama et al. but in the absence of ammonium carbamate and any other sources of N. XPS characterization of a graphite electrode before and after electrolysis in ammonium carbamate soln. suggests that the N species on the C surface may not be as amino groups, but may due to adsorbed ammonium ions or the formation of amides. It is not the surface amino groups that are reacting with catechol, and alternative explanations are discussed. [on SciFinder(R)]
Developmentally regulated expression of the nerve growth factor receptor gene in the periphery and brain. (1987)

Nerve growth factor (NGF) regulates development and maintenance of function of peripheral sympathetic and sensory neurons. A potential role for the trophic factor in brain has been detected only recently. The ability of a cell to respond to NGF is due, in part, to expression of specific receptors on the cell surface. To study tissue-specific expression of the NGF receptor gene, we have used sensitive cRNA probes for detection of NGF receptor mRNA. Our studies indicate that the receptor gene is selectively and specifically expressed in sympathetic (superior cervical) and sensory (dorsal root) ganglia in the periphery, and by the septum-basal forebrain centrally, in the neonatal rat in vivo. Moreover, examination of tissues from neonatal and adult rats reveals a marked reduction in steady-state NGF receptor mRNA levels in sensory ganglia. In contrast, a 2- to 4-fold increase was observed in the basal forebrain and in the sympathetic ganglia over the same time period. Our observations suggest that NGF receptor mRNA expression is developmentally regulated in specific areas of the nervous system in a differential fashion.
Origami Theory And Its Applications: A Literature Review (2013)

This paper presents the fundamentals of Origami engineering and its application in nowadays as well as future industry. Several main cores of mathematical approaches such as Huzita- Hatori axioms, Maekawa and Kawasaki-s theorems are introduced briefly. Meanwhile flaps and circle packing by Robert Lang is explained to make understood the underlying principles in designing crease pattern. Rigid origami and its corrugation patterns which are potentially applicable for creating transformable or temporary spaces is discussed to show the transition of origami from paper to thick material. Moreover, some innovative applications of origami such as eyeglass, origami stent and high tech origami based on mentioned theories and principles are showcased in section III; while some updated origami technology such as Vacuumatics, self-folding of polymer sheets and programmable matter folding which could greatlyenhance origami structureare demonstrated in Section IV to offer more insight in future origami.
Linkage disequilibrium in <i>aquaporin 4</i> gene and association study with schizophrenia (2005)

Aquaporin 4 (AQP4) has an important role in water homeostasis of human brain and a dysfunction of AQP4 could induce pathological conditions in neuronal activity. Several genome scan studies for schizophrenia found a suggestive linkage on 18q, where human AQP4 (18q11.2-12.1) is located nearby. A case-control study was performed which comprised 261 schizophrenia subjects and 278 controls from the Japanese population with four SNP markers. We found strong linkage disequilibrium (LD) and an LD block in the AQP4 gene but found no association between AQP4 and schizophrenia, both single SNP and haplotype analyses. The present study shows that AQP4 is not directly associated with schizophrenia in these Japanese patients.
Voxel Level Radiologic–Pathologic Validation of Restriction Spectrum Imaging Cellularity Index with Gleason Grade in Prostate Cancer (2016)

Building on our previous findings of correlation between GG and the RSI-MRI among whole tumors, our current study reveals a similar correlation at voxel resolution within tumors. Because it can detect variations in tumor grade with voxel-level precision, RSI-MRI may become an option for planning targeted procedures where identifying the area with the most aggressive disease is important. Clin Cancer Res; 22(11); 2668-74. ©2016 AACR.
Tribute to Paul Oberst (2002)

A tribute to Professor Paul Oberst.
Fidaxomicin for the Treatment of Clostridium diffìcile Infections (2012)

Fidaxomicin appears to be an effective and safe alternative to oral vancomycin for treatment of mild-to-moderate and severe CDI. Data on its use compared to guideline-recommended therapies for mild-to-moderate and life-threatening CDI are needed. Further data assessing the cost-effectiveness of fidaxomicin are needed. Currently, it cannot be recommended over vancomycin for treatment of CDI. However, it may be considered for treatment of recurrent infections.
Design of MOFs and intellectual content in reticular chemistry: a personal view (2009)

This article gives a personal perspective on the ideas leading to the development of reticular chemistry. The feasibility of achieving targeted materials with predetermined metrics and functionality by designed synthesis is defended.
Synthesis of Star Polymer Architectures with Site-Isolated Chromophore Cores (2008)

We report the synthesis of star polymers with site-isolated chromophores obtained by nitroxide-mediated polymerization and reversible addition−fragmentation chain transfer techniques through the “arm first” method. Linear polymer precursors such as α-alkoxyamine-terminated polystyrene (PS) and thioester-terminated poly(acrylic acid) (PAA) were prepared followed by the addition of fluorescent divinyl cross-linkers derived from the fluorene and thiophene families. We first synthesized organic soluble star polymers containing hexyl-functionalized fluorene and thiophene cross-linkers with PS. Second, ethylene oxide (EO)-functionalized fluorene cross-linkers were incorporated into PAA linear precursors to give water-soluble star polymers with site-isolated chromophore core units. The photoluminescence increased significantly while the emitting wavelength corresponded with highly dilute, nonconjugated chromophores in solution. This effect is indicative for a highly localized concentration of chomophores in the star polymer cores that are covalently connected but do not show the typical effects of concentrated monomers in solution such as aggregation, fluorescence quenching, and a red shift of emission wavelength. The site isolation of chomophores in star polymers leads to nanostructures with highly photoluminescent core units while the emanating linear polymers are available for further functionalizations.
Transparent Zinc Oxide Films Chemically Prepared from Aqueous Solution (1997)

Transparent zinc oxide (ZnO) films had been chemically deposited on nonconductive glass from aqueous solutions containing zinc nitrate and dimethylamine‐borane (DMAB) kept at 323 K. The ZnO films had a wurtzite structure and exhibited an optical bandgap energy of 3.3 eV which is characteristic of ZnO. A 0.2 μm thick ZnO film with an optical transmittance of 80% was deposited by immersion for approximately 20 min in an aqueous solution containing 0.05 mol/liter zinc nitrate and 0.05 to 0.1 mol/liter DMAB.
An experimental numerical study of the response of a long fibre Bragg grating sensor near a crack tip (2007)

The use of fibre Bragg grating (FBG) sensors and the associated signal interrogation and analysis methods for structural monitoring and micro-mechanics is an important area of research. Long FBG sensors are very well suited for relatively non-invasive detection and measurements of complex strain distributions typically arising when cracks or delaminations are present. However, when the fibre is embedded in a non-homogeneous strain field, the interpretation of its response as a function of the position along the sensor is complicated. Thus, accurate strain data rely on the methods used to decode the wavelength changes and deduce the associated strain distribution. In this paper, the response of a 13 mm long FBG sensor embedded normal to the crack plane in a compact tension specimen of epoxy material is analysed. To introduce highly non-uniform strains along the fibre, a natural crack is grown by cyclic loads and two configurations are investigated: (a) when the fibre is ahead of the crack front, (b) when the fibre is behind the crack front. In both cases, analysis of the signals is carried out using the conventional T-matrix and a method based on optical low-coherence reflectometry (OLCR) and inverse scattering which provides a direct reconstruction of the axial strains in the fibre without any assumptions. The results of the measurements and analysis demonstrated that the predicted spectra from the T-matrix method are not in good agreement with the recorded ones. These differences are attributed to the high strain gradients along the fibre due to its proximity to the crack front. The results from the OLCR-based method directly provide the non-uniform strains along the fibre. The experimental measurements with the latter method are also in good agreement with a three-dimensional numerical model of the actual experimental configuration.
Novel Glycerolipids and Glycolipids from the Surface Lipids of<i>Nicotiana benthamiana</i> (1992)

Journal Article Novel Glycerolipids and Glycolipids from the Surface Lipids of Nicotiana benthamiana Get access Toshiake Matsuzaki, Toshiake Matsuzaki Tobacco Science research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, Japan Search for other works by this author on: Oxford Academic Google Scholar Yasuhiro Shinozaki, Yasuhiro Shinozaki Tobacco Science research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, Japan Search for other works by this author on: Oxford Academic Google Scholar Manabu Hagimori, Manabu Hagimori Tobacco Science research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, JapanApplied Plant Research Laboratory, Japan Tobacco Inc., Oaza Idei 1900, Oyama, Tochigi 323, Japan Search for other works by this author on: Oxford Academic Google Scholar Tetsuya Tobita, Tetsuya Tobita Tobacco Science research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, Japan Search for other works by this author on: Oxford Academic Google Scholar Hitoshi Shigematsu, Hitoshi Shigematsu Tobacco Science research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, Japan Search for other works by this author on: Oxford Academic Google Scholar Akira Koiwai Akira Koiwai Tobacco Science research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, JapanLife Science Research Laboratory, Japan Tobacco Inc., Umegaoka 6–2, Midori-ku, Yokohama 227, Japan Search for other works by this author on: Oxford Academic Google Scholar Bioscience, Biotechnology, and Biochemistry, Volume 56, Issue 10, 1 January 1992, Pages 1565–1569, https://doi.org/10.1271/bbb.56.1565 Published: 01 January 1992 Article history Published: 01 January 1992 Received: 05 March 1992
Effect of Carbonate and Fluoride on the Dissolution Behaviour of Synthetic Apatites (1983)

The initial rates of dissolution of synthetic apatites were determined using the rotating disc method. The reactivities of carbonated apatites in acidic media were directly related to their carbonate content. This appeared to be due, in part, to a decrease in the apparent activation energy for dissolution of carbonated apatites. Structurally incorporated fluoride in carbonated apatites at levels up to 1,000 μg/g did not influence the dissolution rates, whereas fluoride at a concentration of 1 μg/ml in the buffer solution reduced the dissolution rates by 20–30%. Apatite dissolution under the experimental conditions was intermediate between transport control and surface chemical control. After 10 min, diffusion processes within the apatite pellets were found to influence the overall dissolution rate.
Smartphone based Vehicle Tracking and Control via Secured Wireless Networks (2013)

Nowadays, automobile thefts are increasing at an alarming rate all over the world. Security of their vehicle has always been a concern to people. We are developing secured vehicle tracking and control system. In this system the user will be able to control his vehicle through an android based Smartphone. A secured mode of communication between Smartphone and vehicle is established via GSM network. Using his/her Smartphone, the owner will be able to lock/unlock the vehicle and track the vehicle in case of theft. If the GSM network is not available momentarily, a secured Bluetooth channel will be used instead. The project will be helpful in digitization of documents of Regional Transport Office.