gebhart/patrepeval huggingface dataset:
A Direct Interaction between Actin and Vimentin Filaments Mediated by the Tail Domain of Vimentin (2006)

The assembly and organization of the three major eukaryotic cytoskeleton proteins, actin, microtubules, and intermediate filaments, are highly interdependent. Through evolution, cells have developed specialized multifunctional proteins that mediate the cross-linking of these cytoskeleton filament networks. Here we test the hypothesis that two of these filamentous proteins, F-actin and vimentin filament, can interact directly, i.e. in the absence of auxiliary proteins. Through quantitative rheological studies, we find that a mixture of vimentin/actin filament network features a significantly higher stiffness than that of networks containing only actin filaments or only vimentin filaments. Maximum inter-filament interaction occurs at a vimentin/actin molar ratio of 3 to 1. Mixed networks of actin and tailless vimentin filaments show low mechanical stiffness and much weaker inter-filament interactions. Together with the fact that cells featuring prominent vimentin and actin networks are much stiffer than their counterparts lacking an organized actin or vimentin network, these results suggest that actin and vimentin filaments can interact directly through the tail domain of vimentin and that these inter-filament interactions may contribute to the overall mechanical integrity of cells and mediate cytoskeletal cross-talk.
Q-band VCO and injection-locked buffer for 77-GHz automotive radar system in 0.13-µm CMOS (2011)

This paper includes Q-band VCO and high output power injection-locked buffer for 77-GHz FMCW radar system in 0.13-µm CMOS process. The center frequency of the proposed VCO is 34.75-GHz with 1.6% tuning range. The measured phase noise performance shows −102.43 dBc/Hz at 1-MHz offset frequency. The measured maximum single output power is 5.2 dBm and the ideal differential output power is expected to be 8.2 dBm, owing to the injection-locked buffer with a high driving capability. The fabricated chip size is 0.51 × 0.13 mm2. The power consumption of the VCO core and the injection-locked buffer are 10.8 mW and 50.4 mW from a 1.2 V supply, respectively.
A frequency of the quartz crystal microbalance (QCM) that is not affected by the viscosity of a liquid (2008)

The Sauerbrey equation, widely used in quartz crystal microbalances (QCM), expresses the relationship between resonance frequency changes and mass load changes. When a QCM is used in a liquid, however, its resonance frequency is known to be affected not just by the mass load but also by the viscous load of the liquid. Using a network analyzer, we analyzed the impedance of an AT-cut quartz resonator. Based on an admittance diagram given by impedance measurements, the series resonance frequency fs, where conductance is at its maximum, and the two frequencies f1 and f2 (f1 < f2), where conductance is half its maximum, were determined and analyzed at the same time. f1 and f2 are frequencies traditionally used when determining the quality factor for quartz. Focusing on these frequencies, we first conducted an experiment using a 27 MHz quartz resonator in which we changed the liquid temperature of de-ionized water from 26 °C to 62 °C. Changes in liquid temperature allowed measurement of the effect of viscosity changes in the de-ionized water on the above frequencies. Results revealed a rise in frequency of about 2500 Hz for fs and about 100 Hz for f2. Next, we measured the effects of each frequency when the liquid was changed to a glycerol concentration of 0–14 wt% and an ethanol concentration of 0–10 wt%. fs was affected by viscosity, which changed due to the rise in concentration. This frequency change coincided for the most part with theoretical values representing the viscous load of the liquid. f2, however, was mostly unaffected by viscosity, which changed as a result of the rise in concentration. Then, we performed measurement with a mixture of avidin and glycerol. The frequency change for fs was about −50 Hz while that for f2 was about −30 Hz. When, as a reference, a solution of avidin alone was added, the frequency change for both fs and f2 was about −30 Hz. When glycerol alone was added, the frequency change for fs was about −25 Hz, but there was no frequency change for f2. Based on theory and the above measurement results, f2 was found to have characteristics that are not affected by the viscous load of a Newtonian liquid. Thus, using f2 for a QCM subject to viscous changes in a liquid allowed more accurate determination of the mass load than fs.
경장영양이 필요한 환자에서 경장영양 펌프의 효과: 체계적 문헌 분석 (2014)

목적: 경장영양펌프 사용의 안전성 및 유효성에 대한 연구 문헌을 총괄 정리함으로써 현실에 맞는 경장영양펌프 사용기준을 마련해 보고자 하였다. 대상 및 방법: 첫째, 임상적 유용성을 가인드라인을 통해 검토하였고, 둘째, 안전성과 유효성을 체계적 문헌고찰을 통해 검토하였다. 경장영양펌프를 이용한 관급식 요법은 8개 국내 데이터베이스와 Ovid-MEDLINE, Ovid-EMBASE 및 Cochrane Library 등의 국외 데이터베이스를 이용하였다. 관련문헌은“(enteral feeding.mp AND pump.mp)”와 관련된 검색어를 활용하여 총 2,016편의 문헌이 검색되었고, 중복 문헌(686편)배제 후 선택/배제기준을 적용하여 총 11편이 최종 평가에 포함되었다. 문헌검색부터 선택기준 적용 및 자료추출까지 각단계는 모두 소위원회와 아울러 2명의 평가자가 각 과정을 독립적으로 수행하였으며, 문헌의 질 평가는 SIGN의 도구를 이용하였고 이에 따라 근거의 수준과 권고의 등급을 선정하였다. 결과: 유용성 검토 결과, 경장영양펌프를 이용한 관급식 요법에 대해 연구한 각 문헌에서 사용한 영양액 종류, 주입속도, 튜브의 크기가 모두 달라 경장영양펌프의 효과에 대한 결론을 낼 수는 없었으나, 소장급식관을 통하여 경관급식을 해야 하는 환자, 위장급식관을 통하여 영양액을 경관급식해야 하는 중증환자, 미숙아, 중증 및 영양공급 불량아동에게 경장영양펌프 사용이 권고된 것은 타당하다는 결론에 전문가 그룹은 합의하였다. 체계적 문헌고찰 결과, 경장영양펌프를 이용한 경관급식 요법의 안전성은 합병증 발생률을 주요지표로 평가하였으며, 모두 임상적으로 허용할 수 있는 수준이었고, 경장영양 부적응 관련 합병증 발생 가능성을 줄여주어 안전하다고 보고되었다. 유효성은 경장영양 적응도를 보고한 연구에서 동일한 결과로 기술되지 않았지만, 소장급식관을 통하여 경관급식 받는 환자, 위장급식관을 통하여 영양액을 경관급식 받는 중증환자, 미숙아, 중증 및 영양공급이 불량한 아동의 경우, 펌프를 사용하지 않고 경장영양액 주입 시 직접 영양액이 투여되는 위장관내의 특정 부위의 단위 시간당 수용 가능한 용적의 한계성을 넘게 되는 위험으로 인해 경장영양 부적응 관련 합병증 발생 가능성이 높기 때문에 경장영양펌프 사용이 필요하다는 인식을 함께 하였다. 결론: 경장영양펌프를 이용한 경관급식 요법은 소장급식관을 통하여 경관급식을 받는 환자, 위장급식관을 통하여 영양액을 경관급식 받는 중증환자, 미숙아, 중증 및 영양공급이 불량한 아동을 대상으로 안전성 및 유효성의 근거가 있는 기술로 평가된다(권고등급 D).
Montelukast, Compared With Fluticasone, for Control of Asthma Among 6- to 14-Year-Old Patients With Mild Asthma: The MOSAIC Study (2005)

Montelukast was demonstrated to be not inferior to fluticasone in increasing the percentage of RFDs among 6- to 14-year-old patients with mild asthma. Secondary end points, including percentage of predicted forced expiratory volume in 1 second value, days with beta-receptor agonist use, and quality of life, improved in both groups but were significantly better in the fluticasone treatment group.
Fetal vibroacoustic stimulation test: vibrator response characteristics in pregnant sheep postmortem. (1993)

Routine verification of the function of a vibroacoustic device by means of a battery voltage check is recommended.
Reducing the Violence in Our Homes (1994)

Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional: July 1994 - Volume 12 - Issue 4 - p 74-76
Cycloaddition reactions of 2,2,2-trifluorodiazoethane (1968)

2,2,2-Trifluorodiazoethane readily forms cyclopropanes when photolysed with suitable olefins. In the absence of light, a typical 1,3-dipolar addition gives Δ1-pyrazolines. This reaction, slow with ethylene, is retarded by alkyl substituents on the vinylic carbon, but accelerated slightly by halogens other than fluorine; a trifluoromethyl group has an accelerating effect of the same order of magnitude as an alkoxycarbonyl group.
Affinity Purification of Autoantibodies from an Antigen Strip Excised from a Nitrocellulose Protein Blot (2009)

A method for the affinity purification of autoantibodies from small volumes of human sera using a western blot strip containing a target antigen electrophoretically transferred from a sodium dodecyl sulfate (SDS) polyacrylamide gel is described. This method is a very useful alternative for affinity column chromatography, particularly when the antigen of interest is of low abundance. The protein mixture is resolved on a preparative SDS polyacrylamide gel and transferred to nitrocellulose membrane. A couple of strips are excised vertically from either side of the blotted membrane and immunoblotted with specific antisera to identify the target band. Then the target band is excised horizontally and used for affinity purification. We have used this procedure to affinity purify antibodies to a 70,000 molecular weight protein derived from HeLa cell extract. A sham band, excised away from the target antigen, was used as a control for sham purification of autoantibodies. The autoantibodies purified in this manner reproduced the multiple nuclear dot anti-nuclear antibody pattern obtained using crude sera from 21 patients without primary biliary cirrhosis or anti-mitochondrial antibody.
Istanbul Bogazı’nda Meydana Gelen Deniz Kazalarının İncelenmesi ve Analizi (2011)

Istanbul Bogazi dar bir su yolu olup Karadeniz’i Marmara Denizi’ne baglamaktadir. Istanbul Bogazi’nin dar ve derin olmasi, akintilar ve kotu hava kosullari gibi cografi ve seyri sinirlayici kosullari deniz kazalarinin baslica nedeni olmaktadir. Calismada, Istanbul Bogazi’nin cografi, meterolojik, hidrografik ve osinografik, stratejik ve cevresel ozellikleri, seyir duzenleri ve deniz trafigi, deniz kazalari genel olarak incelenmistir. Istanbul Bogazi’nda “Sag Seyir Duzeni”nin uygulandigi 1982 yilindan 2008 yili sonuna kadar meydana gelen kazalara iliskin Frekans Dagilimi ve Ikili iliski Analizi (χ2) gibi istatistiksel analizler yapilmistir. Genel bir degerlendirme yapilmis olup Istanbul Bogazi’nda meydana gelebilecek kazalarin onlenmesine iliskin alinmasi gereken onlemler onerilmistir
Spectrum of melanoma antigens on cultured human malignant melanoma cells as detected by monkey antibodies. (1979)

To characterize the antigen present on the surface of cultured human malignant melanoma, three monkey xenogeneic antisera were raised. After appropriate absorption with pooled human erythrocytes, peripheral blood leukocytes, and liver homogenate, no blood group or HLA reactivity was detectable. Analysis of melanoma antigenic specificity was performed by the mixed hemadsorption microassay on live monolayer cells in conjunction with quantitative microabsorption analysis. To eliminate reactivity against nonmelanoma lines, 2 of the 3 antisera required further absorption with cells of the KB oral carcinoma line. The absorbed antisera reacted with 9 of 10 long-term established lines, 3 of 3 short-term cultures of human malignant melanoma, and 1 of 10 nonmelanoma epithelial and fibroblastic cell lines. Absorption experiments using a variety of cultured cells and fresh tissue homogenates of adult human melanoma and nonmelanoma sources further substantiated the results obtained with the direct tests. While each melanoma line showed a differing degree and pattern of reactivity, the antisera were most reactive against their respective immunizing lines as revealed by both the direct tests and absorption analysis. By quantitative absorption analysis, no evidence for individually specific melanoma antigens was obtained. The only positive absorption with nonmelanoma adult tissues was obtained with a retinoblastoma cell line, indicating the presence of antigens shared by tumors of common neuroectodermal origin. Extensive absorption with two xenogeneic malignant melanoma (murine and porcine) homogenates, normal human adult skin, and spleen tissues, or Bacillus Calmette-Guerin failed to reduce the reactivity against melanoma-associated antigens. Further absorption with human fetal tissues of 8 to 20 weeks of gestation removed part but not all of the reactivity. These studies with xenogeneic monkey antisera provide evidence for the existence of common melanoma-associated antigens as well as distinct but shared human fetal antigens on human melanoma cells.
Industrial Training in France (with Reference to the New Micro‐electronic Technology) (1986)

In the following article, a brief account of the French industrial training system is presented, to be followed by an outline of the changing industrial structure observed in the Saint‐Etienne area, with particular reference to the adoption of new technology in manufacturing systems and observations concerning the local industrial training structure which has emerged to facilitate such changes. Concluding remarks contrast the French situation regarding continuing training provision with the relative absence of such provision in Britain.
A Versatile Embedded Platform for EMG Acquisition and Gesture Recognition (2015)

Wearable devices offer interesting features, such as low cost and user friendliness, but their use for medical applications is an open research topic, given the limited hardware resources they provide. In this paper, we present an embedded solution for real-time EMG-based hand gesture recognition. The work focuses on the multi-level design of the system, integrating the hardware and software components to develop a wearable device capable of acquiring and processing EMG signals for real-time gesture recognition. The system combines the accuracy of a custom analog front end with the flexibility of a low power and high performance microcontroller for on-board processing. Our system achieves the same accuracy of high-end and more expensive active EMG sensors used in applications with strict requirements on signal quality. At the same time, due to its flexible configuration, it can be compared to the few wearable platforms designed for EMG gesture recognition available on market. We demonstrate that we reach similar or better performance while embedding the gesture recognition on board, with the benefit of cost reduction. To validate this approach, we collected a dataset of 7 gestures from 4 users, which were used to evaluate the impact of the number of EMG channels, the number of recognized gestures and the data rate on the recognition accuracy and on the computational demand of the classifier. As a result, we implemented a SVM recognition algorithm capable of real-time performance on the proposed wearable platform, achieving a classification rate of 90%, which is aligned with the state-of-the-art off-line results and a 29.7 mW power consumption, guaranteeing 44 hours of continuous operation with a 400 mAh battery.
Injection of a porcine sperm factor triggers calcium oscillations in mouse oocytes and bovine eggs (1997)

Fertilization in mammals is associated with the generation of intracellular calcium ([Ca2+]i) oscillations. The site of, or mechanism(s) utilized by, the sperm to initiate and maintain these Ca2+ responses is not known. In this study, we tested the hypothesis that a factor from the sperm is capable, upon release into the oocyte's cytosol, of initiating oscillations. A sperm factor, prepared from porcine semen, was injected into mouse oocytes and bovine eggs that had been loaded with fura-2 dextran, a fluorescent Ca2+ indicator. The resulting Ca2+ responses were monitored and compared to those characteristic of each species. Our results show that injection of sperm factor triggered long-lasting [Ca2+]i oscillations, and that the observed patterns were species-specific. In mouse oocytes, sperm factor-induced [Ca2+]i rises exhibited high frequency, whereas in bovine eggs, Ca2+ responses were separated by long intervals. Further characterization of the sperm factor revealed that it was predominantly present in sperm preparations, that it contained a protein moiety, and that it was unlikely to be a protease. The intracellular Ca2+ channels/receptors through which the sperm factor-mediated Ca2+ release was investigated by using heparin, a competitive inhibitor of the inositol 1,4,5 trisphosphate receptor (InsP3R), and ryanodine, which binds the ryanodine receptor (RyR). The sperm factor appeared to stimulate InsP3R, at least in mouse oocytes, because sperm factor-induced oscillations were delayed or blocked in all oocytes by injection of heparin. RyR may be involved in the modulation of these oscillations, since addition of ryanodine modified Ca2+ responses to the sperm factor. The present results support the hypothesis that a factor from the sperm is involved in the generation of fertilization-associated [Ca2+]i oscillations.
Uso del alcohol, tabaco y drogas en colegiales adolescentes. Correlacion con el medio en el que conviven, personalidad y conducta. Estudio comparativo 1984-1987 (1988)

Se ha realizado un triple estudio: el consumo del alcohol, tabaco y drogas, la correlacion de este consumo con la llamada influencia psicosocial, resultante de la interacion persona-ambiente, basado en la teoria de campo de las ciencias sociales de kurt lewin, (ambiente de convivencia. Personalidad y conducta del individuo). Y un estudio comparativo entre los anos 1984 y 1987, periodo que engloba al bienia 1985-1986 en el que se llevo a cabo el plan nacional antidroga. Se ha llevado a cabo sobre 1463 adolescentes escolarizados mediante una tecnica de muestreo probabilista de etapas multiples. Definiendose dentro de los consumidores de alcohol los conceptos de bebedores , no bebedores , presuntos bebedores y bebedores de fin de semana , bebedores de todos los dias , asi como el de grupo de alto riesgo de alcoholismo . De igual forma se han carazterizado varios estereotipos de adolescentes integrando e interrelacionando la llamada infuencia psicosocion calidad y cantidad de consumo de alcohol, tabaco y drogas y sensaciones subjetivas que las provoca. Las causas que llevan al consumo de drogas y los indices de ansiedad y neurotizacion de la muestra. En el ano 1987 con relacion a 1984, se ha incrementado el consumo de alcohol y tabaco, existiendo una mayor tendencia al consumo de cocaina. Existe una correlacion multiple positiva entre el grupo de consumidores de alcohol calificado como bebedores y los adolescentes que conviven en un ambiente familiar problematico, poseen una personalidad problematica ansiosa o neurotica y una forma de actuacion problematica. Se ha encontrado una tendencia de los adolescentes consumidores de bebidas con un alto contenido alcoholico y de cerveza a pertenecer al grupo calificado como bebedores y por tanto como grupo de alto riesgo de alcoholismo. Este grupo implica al 59% de la muestra estudiada. Los adolescentes consumidores de bebidas alcoholicas de contenido medio en etanol y de vino, tie
Effect of external tank nose shape on the Rockwell International space shuttle vehicle 3, integrated configuration (IA37B) (1974)

Tests of several tank nose shapes were conducted as a part of the investigation of configuration changes to reduce drag for the integrated vehicle. The effect on the integrated vehicle aerodynamic characteristics of several tank nose shapes was investigated. The tank nose shapes investigated were the 600 inch (baseline) and 1204 inch radius ogives, and the 600 inch ogive plus a spike 360 inches long and 12.0 inches in diameter. Data were obtained over a Mach number range of 0.6 through 4.96 and for angles-of-attack and sideslip from -10 through +10 degrees. The model used was the 0.004-scale integrated vehicle model number 34-OTS.
Detection and measurement of alpha-fetoprotein in human breast cancer cytosol after treatment with 0.4 M potassium chloride. (1983)

The mean concentration of total alpha-fetoprotein (AFP) measured in 51 primary breast cancer cytosols from postmenopausal women by radioimmunoassay after treatment with 0.4 M KCl was 87.2 IU AFP per ml. Little or no AFP was measured in these same cytosols before KCl treatment. After labeling KCl-treated human breast cancer cytosols with 125I, double immunodiffusion, immunoelectrophoresis, and autoradiography revealed that radiolabeled AFP codiffused and comigrated with alpha 1 electrophoretic mobility in a manner identical to that of added carrier cord serum AFP. These results indicate that human breast cancer cytosol contains appreciable amounts of a previously undetected AFP component that was initially nonimmunoreactive but became immunoreactive and measurable after KCl treatment. No positive correlation was found between the initial estrogen receptor content and AFP concentrations measured either before or after KCl treatment of breast cancer cytosols.
Direct Imaging of Complex Nano- to Microscale Interfaces Involving Solid, Liquid, and Gas Phases (2012)

Surfaces with special wetting properties not only can efficiently repel or attract liquids such as water and oils but also can prevent formation of biofilms, ice, and clathrate hydrates. Predicting the wetting properties of these special surfaces requires detailed knowledge of the composition and geometry of the interfacial region between the droplet and the underlying substrate. In this work we introduce a 3D quantitative method for direct nanoscale visualization of such interfaces. Specifically, we demonstrate direct nano- to microscale imaging of complex fluidic interfaces using cryostabilization in combination with cryogenic focused ion beam milling and SEM imaging. We show that application of this method yields quantitative information about the interfacial geometry of water condensate on superhydrophilic, superhydrophobic, and lubricant-impregnated surfaces with previously unattainable nanoscale resolution. This type of information is crucial to a fundamental understanding as well as the design of surfaces with special wetting properties.
Absolute concentration measurements of CH radicals in a diamond-depositing dc-arcjet reactor (1997)

Laser-induced fluorescence in the CH (B - X) and CH (A - X) electronic transitions is used to measure absolute number density versus position for CH radicals in the plume of a 25-Torr hydrogen/argon/methane (0.8:1:0.005) dc arcjet during the chemical vapor deposition of diamond film. The laser-induced-fluorescence signal is calibrated with argon Rayleigh scattering, and the resultant concentration of the CH radical in the center of the arcjet plume is found to be (3.5 +/- 0.8) x 10(12) molecules/cm(3). The characterization of the plasma plume shows three different regions in the reacting gas: nozzle, plume, and boundary layer. We observe substantial differences in spatial distribution of gas temperature, collisional quenching, and CH number density among these regions.
Internal Medicine for Dentistry (1983)

Preface. Introduction. The Fundamentals of the Science and Technology of Ultrasonics: Vibratory and Wave Motion. Ultrasonic Technology. The Physical Principles of Ultrasonic Treatment of Liquid Metals: Ultrasonic Cavitation. Acoustic Streaming, Radiation Pressure and Sonocapillary Effect. Ultrasonic Atomization and Degassing of Liquids. Solidification of Metals in an Ultrasonic Field. The Physical Principles of Ultrasonic Treatment of Solid Metals: The Attenuation of Ultrasonic Vibrations in Solids. Structure Changes in Metals on Ultrasonic Stressing. Mechanical Properties of Ultrasonically Irradiated Metals. Diffusion in an Ultrasonic Field. Phase Transformations in Ultrasonically Irradiated Metals. Ultrasound Interaction with the Solid-Solid Contact Surface. High-Intensity Ultrasound in Liquid Metal Technologies: Ultrasonic Degassing of the Melt. Solidification of Metals in an Ultrasonic Field. Ultrasonically Assisted Crystal Growth. Ultrasound in Plating Processes. Ultrasonic Melt Atomization in Powder Metallurgy. The Use of Ultrasound for Preparing In Situ Composites. High-Intensity Ultrasound in Solid Metal Technologies: Ultrasound in Metalworking Processes. Ultrasound in Heat Treatment and Chemical Heat Treatment. Ultrasonic Machining. Ultrasonic Surface Hardening.
Soil, water, and plant relations. (1970)

Our results highlight that physical complaints commonly addressed by physical therapists on their interventions are not the only impediments to reduce sedentary behavior. Important individual and social barriers should not be neglected when physical therapists conduct interventions to reduce sedentary behavior to maximize functional recovery in older adults after hip fracture surgery. Future clinical trials are required to investigate the effectiveness of more comprehensive interventions to reduce sedentary behavior in this population.