gebhart/patrepeval huggingface dataset:
A wide frequency range and adjustable duty cycle CMOS ring voltage controlled oscillator (2010)

This paper presents a voltage controlled ring oscillator (VCO) with wide tuning range and adjustable duty cycle. The circuit was designed using Rohm 0.18μm technology with 1.5V supply voltage. The simulation results show that the VCO oscillates from 300Hz up to 1.4GHz, while the duty cycle can be adjusted 20-80% independently from the oscillating frequency.
Cost-effective Heuristics for Workflow Scheduling in Grid Computing Economy (2007)

The increasing demand for grid computing resources calls for an incentive-compatible pricing mechanism for differentiated service qualities. Cost-effective scheduling of grid workflow applications described by directed acyclic graph (DAG) becomes an essential and complex problem. In general, the optimization problem is NP-hard, and heuristics are among the methods of choice. In this paper, in order to taking advantage of the workflow deadline, several priority rules are developed, which take into account both activity information and service levels information. To invalidate their effectiveness, these priority rules are applied to different initial solutions. Computational experiments show that two heuristics combining priority rules GRBPA, GRPA with starting solution HL can achieve the better results than heuristics based on other priority rules.
STRUCTURE AND REACTIONS OF CYCLOSERINE<sup>1</sup> (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSTRUCTURE AND REACTIONS OF CYCLOSERINE1Phil H. Hidy, E. B. Hodge, Vernon V. Young, Roger L. Harned, Glenn A. Brewer, W. F. Phillips, W. F. Runge, Homer E. Stavely, A. Pohland, H. Boaz, and H. R. SullivanCite this: J. Am. Chem. Soc. 1955, 77, 8, 2345–2346Publication Date (Print):April 1, 1955Publication History Published online1 May 2002Published inissue 1 April 1955https://pubs.acs.org/doi/10.1021/ja01613a106https://doi.org/10.1021/ja01613a106research-articleACS PublicationsRequest reuse permissionsArticle Views432Altmetric-Citations95LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
2. The Continuous Wavelet Transform (1992)

The images of -functions under the continuous wavelet transform constitute a reproducing kernel Hilbert space (r.k.H.s.). Such r.k.H.s.'s occur and are useful in many different contexts. One of the simplest examples is the space of all bandlimited functions, discussed in §§2.1 and 2.2. In §2.3 we introduce the concept of band and time limiting; of course no nonzero function can be strictly time-limited (i.e., for t outside [−T,T]) and band-limited ( for ), but one can still introduce time-and-band-limiting operators. We present a short review of the beautiful work of Landau, Pollak, and Slepian on this subject. We then switch to the continuous wavelet transform: the resolution of the identity in §2.4 (with a proof of (1.3.1)), the corresponding r.k.H.s. in §2.5. In §2.6 we briefly show how the one-dimensional results of the earlier sections can be extended to higher dimensions. In §2.7 we draw a parallel with the continuous windowed Fourier transform. In §2.8 we show how a different kind of time-and-band-limiting operator can be built from the continuous windowed Fourier transform or from the wavelet transform. Finally, we comment in §2.9 on the “zoom-in” property of the wavelet transform.
The anti-progestin RU486 stabilizes the progestin-induced fatty acid synthetase mRNA but does not stimulate its transcription (1991)

Progestins induce fatty acid synthetase (FAS) in breast cancer cell lines, both increasing its gene transcription and mRNA stabilization (Joyeux, C., Rochefort, H., and Chalbos, D. (1989) Mol. Endocrinol. 4, 681-686). In vitro run-on transcription assays show that RU486, in contrast to progestin, inhibits FAS transcription by 40-50%. Moreover and surprisingly, anti-progestin RU486 also stabilizes FAS mRNA 3- to 4-fold in MCF7 cells as measured by chase experiments in the presence of actinomycin D or cordycepin or after short cell labeling with [3H]uridine. Dexamethasone is inefficient in increasing the half-life of FAS mRNA in MCF7 cells. RU486 had no effect on MDA-MB 231 cells which contain glucocorticoid but no progesterone receptors, indicating that the progesterone receptor is implicated in this regulation. RU486-induced mRNA stabilization allows delayed accumulation of FAS mRNA. These results indicate that the progesterone receptor can be activated separately to stimulate gene transcription or stabilize mRNA.
Multi-vendor auto-connectivity in heterogeneous networks (2013)

Abstract—Heterogeneous radio networks (HetNet) consist of base stations and other Network Elements (NE) manufactured by various vendors, providing service at overlapping coverage areas supporting different Radio Access Technologies (RAT). This heterogeneity increases the complexity of network management functions as the required infrastructure, configuration sequences and protocols vary across vendors. The diversity also makes the automation of initial configuration (referred to as self-configuration or “plug-and-play”) an essential element in providing easier and faster network roll-out and base station deployment, especially considering emerging RATs such as Long Term Evolution (LTE) and beyond. Therefore, the need for a simple, unified auto-connectivity has become increasingly important with the evolution of 3G and LTE deployments towards HetNet infrastructures. In this paper, a novel multi-vendor capable selfconfiguration architecture is presented, which was inspired by real network deployment and auto-configuration scenarios. The proposed framework is able to provide a unified initial connectivity sequence for new network elements including base stations supporting different RATs. Additionally, the proposed apparatus is also prepared for handling multiple Domain Manager (DM) instances under the supervision of the same vendor and within the same RAT. The standardization impacts of the proposed architecture and the required technologies are discussed as well. Keywords—Auto-connectivity; multi-vendor; plug-and-play; self-configuration I.
Video summarization using shot segmentation and local motion estimation (2012)

The video used by professionals from various fields and the general public is constantly growing, it's important to develop efficient systems to classify and index them. The video summarization is an essential step to construct a system of indexing and searching video, it's the process to create a short video presentation and a global vision on the important scenes of the video. This summarization consist to extract keyframes to present video content, it's similar to extract the keywords from text document. Mainly summarization methods apply clustering algorithms to all video frames. There are computations expensive because they use a dissimilarity matrix which implies a quadratic calculation. In this context, we present a new technique for extracting video summary using an adapted shot segmentation. We apply a hierarchical clustering in each shot to extract the keyframes; the number of these keyframes is proportional to variations and movements in the shot. We propose a local motion estimation, we use a co-occurrence matrix to measure the dissimilarity between shot frames and to take account the motion in the shot.
Analytical Toxicology (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalytical ToxicologyIrving SunshineCite this: Anal. Chem. 1975, 47, 2, 212A–215APublication Date (Print):February 1, 1975Publication History Published online24 May 2012Published inissue 1 February 1975https://pubs.acs.org/doi/10.1021/ac60352a795https://doi.org/10.1021/ac60352a795research-articleACS PublicationsRequest reuse permissionsArticle Views44Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Next generation approaches for tumor vaccination (2017)

Tumor vaccines have been an attractive concept in the immunotherapy of cancer based on the central role of tumor-associated antigens in allowing the immune system to recognize cancer cells and the large variety of platforms in which to present such antigens to the immune system. Early clinical studies of vaccines, however, were largely disappointing. Recent evidence that cancer-mediated T cell suppression may prevent T cell activation is leading to renewed interest in vaccine development. The use of T cell checkpoint inhibitors alone has revolutionized the contemporary treatment of human cancer, and has suggested that the emergence of neoantigens may be an important biomarker of therapeutic response. Thus, the possibility of using more personalized vaccines targeting relevant neoantigens alone and in combination with T cell checkpoint blockade is a new area of active clinical investigation. In this review we will discuss the central role of antigens in tumor immunotherapy, describe how vaccines may be developed in the context of modern genomic profiling of tumor cells and provide a forward looking perspective on how tumor vaccines may be incorporated into the current landscape of cancer therapy.
Interband Phase Modes and Nonequilibrium Soliton Structures in Two-Gap Superconductors (2003)

We predict a new dynamic state in current-carrying superconductors with a multicomponent order parameter. If the current density J exceeds a critical value J(t), an interband breakdown caused by charge imbalance of nonequilibrium quasiparticles occurs. For J>J(t), the electric field penetrating from current leads gives rise to various static and dynamic soliton phase textures, and voltage oscillations similar to the nonstationary Josephson effect. We propose experiments to observe these effects which would probe the multicomponent nature of the superconducting order parameter.
Vertically coupled GaInAsP–InP microring resonators (2001)

Vertically coupled microring resonator channel-dropping filters are demonstrated in the GaInAsP-InP material system. These devices were fabricated without regrowth. In this method, low-loss single-mode waveguides are removed from the growth substrate and bonded to a GaAs transfer substrate with benzocyclobutene. This permits fabrication of vertically coupled waveguides on both sides of the epilayer. Optical quality facets are obtained by cleaving through the transfer substrate. Operation of single-mode, single-ring optical channel-dropping filters is demonstrated.
Studies on Heterocyclic Compounds. XII. A Novel Synthesis of 5-Oxo- and 7-Oxo-pyrido [2, 3-d] pyrimidines (1973)

A simple synthesis of pyrido [2, 3-d] pyrimidine derivatives as an antitumor agent was reported. Reaction of 6-amino- and 6-(substituted) amino-1, 3-dimethyluracil (I) with dimethyl acetylenedicarboxylate in methanol afforded a mixture of 5-oxo- and 7-oxopyrido-[2, 3-d] pyrimidines and an open-chain intermediate. This intermediate was proved to be 5-substituted 6-aminopyrimidine (VIa), and to be cyclized to 7-oxopyrido [2, 3-d] pyrimidine (VIIIa). On the other hand, 5-oxo compounds were obtained from the reaction of I with diketene or ethyl acetoacetate.
Kangaroo – A pattern-matching program for biological sequences (2002)

A low-level simple pattern-matching application can prove to be a useful tool in many research settings. For example, Kangaroo was used to identify potential genetic targets in a human colorectal cancer variant that is characterized by a high frequency of mutations in coding regions containing mononucleotide repeats.
A STE12 Homolog Is Required for Mating but Dispensable for Filamentation in <i>Candida lusitaniae</i> (2000)

Candida lusitaniae is a dimorphic yeast that is emerging as an opportunistic fungal pathogen. In contrast to Candida albicans, which is diploid and asexual, C. lusitaniae has been reported to have a sexual cycle. We have employed genetic approaches to demonstrate that C. lusitaniae is haploid and has a sexual cycle involving mating between MATa and MATalpha cells under nutrient deprivation conditions. By degenerate PCR, we identified a C. lusitaniae homolog (Cls12) of the Ste12 transcription factor that regulates mating, filamentation, and virulence in Saccharomyces cerevisiae, C. albicans, and Cryptococcus neoformans. Comparison of the CLS12 DNA and protein sequences to other STE12 homologs and transformation experiments with selectable markers from S. cerevisiae (URA3, KanMX, HphMX) and C. albicans (CaURA3) provide evidence that the CUG codon encodes serine instead of leucine in C. lusitaniae, as is also the case in C. albicans. The C. lusitaniae CLS12 gene was disrupted by biolistic transformation and homologous recombination. C. lusitaniae cls12 mutant strains were sterile but had no defect in filamentous growth. Our findings reveal both conserved and divergent roles for the C. lusitaniae STE12 homolog in regulating differentiation of this emerging fungal pathogen.
Color Variations in Glasses Containing Iron (1948)

The variations of the color of iron glasses are due to the fluctuations in (a) concentration, and (b) oxidation-reduction equilibrium. In an experimental series, changes of these two variables were exaggerated. An increase in concentration caused a decrease in transmission and a shift to higher dominant wave-lengths (yellow), while reduction caused a decrease in transmission and a shift to lower dominant wave-lengths (blue). The changes in chromaticity were evaluated and applied to problems of control and specification. The Nickerson-Balinkin small color difference formula indicated a modification of existing specifications in transmission and dominant wave-length with tolerances equal in three color dimensions.
The Measurement of Combustible Properties of Cyclohexanol (2014)

사이클로헥산올의 안전한 취급을 위해, 폭발한계는 문헌을 통해 고찰하였고, 인화점과 발화지연시간에 의한 발화온도를 측정하였다. 그 결과, 밀폐식 장치에 의한 사이클로헥산올의 하부인화점은<TEX>$60^{\circ}C{\sim}64^{\circ}C$</TEX>로 측정되었으며, 개방식에서는 <TEX>$66^{\circ}C{\sim}68^{\circ}C$</TEX>로 측정되었다. ASTM E659 장치를 사용하여 자연발화온도와 발화지연시간을 측정하였고, 사이클로헥산올의 최소자연발화온도는 <TEX>$297^{\circ}C$</TEX>로 측정되었다. 측정된 하부인화점과 상부인화점에 의한 폭발하한계는 0.95 Vol%, 상한계는 10.7 Vol%로 계산되었다. For the safe handling of cyclohexanol, this study was investigated the explosion limits of cyclohexanol in the reference data. The flash points and auto-ignition temperatures (AITs) by ignition delay time were experimented. The lower flash points of cyclohexanol by using closed-cup tester were experimented in<TEX>$60^{\circ}C{\sim}64^{\circ}C$</TEX>. The lower flash points of cyclohexanol by using open cup tester were experimented in <TEX>$66^{\circ}C{\sim}68^{\circ}C$</TEX>. This study measured relationship between the AITs and the ignition delay times by using ASTM E659 tester for cyclohexanol. The AIT of cyclohexanol was experimented as <TEX>$297^{\circ}C$</TEX>. The lower explosion limit (LEL) and the upper explosion limit UEL) by the measured the lower flash point and the upper flash point of cyclohexanol were calculated as 0.95 Vol% and 10.7 Vol%, respectively.
T Cell Receptor-Extracellular Constant Regions as Hetero-Cross-Linkers for Immunoglobulin Variable Regions (1993)

The T cell receptor alpha and beta chains are covalently linked via a disulfide bond in their extracellular constant regions. To use these domains as specific hetero-cross-linkers of two different polypeptides, we created genetic constructs encoding a chimeric antibody Fab fragment in which mouse immunoglobulin constant regions from a phosphorylcholine-specific antibody were substituted for human alpha beta-T cell receptor (TCR) extracellular constant regions (for solubilization, the transmembrane- and cytoplasmic-regions of the receptor were deleted). These constructs, i.e., chimeric heavy (VHC beta C kappa) and light (VLC alpha) chains, were cotransfected into murine SP2/0 myeloma cells for expression. Cells transfected with the genes expressed mRNAs for chimeric heavy and light chains. Without CD3 molecules, the two chimeric chains specifically associated via a disulfide bond to form a chimeric Fab fragment in the cells. These data indicate that the TCR C alpha- and C beta-regions might be used as potent specific hetero-cross-linkers for protein engineering.
Low-Complexity Algorithms in Digital Receivers (1996)

This thesis addresses low-complexity algorithms in digital receivers. This includes algorithms for estimation, detection, and source coding.
Musculoskeletal disorders in nursing (2003)

Musculoskeletal disorders (MSD) represent one of the most frequently occurring and costly occupational issue in nursing. Low back pain is probably the most important, individual MSD subcategory within the nursing profession. Although risk factors are known to include personal features such as age and fitness levels, workplace factors such as patient handling, work posture and job category are usually more important predictors. Limited job control and lack of social support from colleagues may also contribute. The development and use of sound ergonomic practices is an important step in the reduction of MSD among nurses. (non-author abstract)
Learning Semantic Vector Representations of Source Code via a Siamese Neural Network (2019)

The abundance of open-source code, coupled with the success of recent advances in deep learning for natural language processing, has given rise to a promising new application of machine learning to source code. In this work, we explore the use of a Siamese recurrent neural network model on Python source code to create vectors which capture the semantics of code. We evaluate the quality of embeddings by identifying which problem from a programming competition the code solves. Our model significantly outperforms a bag-of-tokens embedding, providing promising results for improving code embeddings that can be used in future software engineering tasks.
Condensation (2004)

Condensation is a separation process in which one or more volatile components of a vapor mixture are separated from the remaining vapors through saturation followed by a phase change (see Fig. 1). The phase change from gas to liquid can be accomplished in two ways: (1) the system pressure may be increased at a given temperature or (2) the system temperature may be reduced at a given pressure. Condensation occurs when the vapor-phase partial pressure of a volatile component exceeds that of the component in the liquid phase (or the vapor pressure for a pure liquid phase). Condensers are the unit operations primarily used to remove volatile organic compounds (VOCs) from gas streams prior to other controls such as incinerators or absorbers, but can sometimes be used alone to reduce emissions from high-VOC-concentration gas streams.
The aquaporin-4 water channel as a potential drug target in neurological disorders (2017)

Aquaporin-4 (AQP4) is a water transporting protein expressed at the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis of AQP4 knockout mice has suggested its broad involvement in brain water balance, neuroexcitation, glial scarring, neuroinflammation, and even neurodegenerative and neuropsychiatric disorders. Broad clinical utility of AQP4 modulators has been speculated. Area covered: This review covers the biology of AQP4, evidence for its roles in normal CNS function and neurological disorders, and progress in AQP4 drug discovery. Expert opinion: Critical examination of available data reduces the lengthy potential applications list to AQP4 inhibitors for early therapy of ischemic stroke and perhaps for reduction of glial scarring following CNS injury. Major challenges in identification and clinical development of AQP4 inhibitors include the apparent poor druggability of AQPs, the many homologous AQP isoforms with broad tissue distribution and functions, technical issues with water transport assays, predicted undesired CNS and non-CNS actions, and the need for high blood-brain barrier permeation. To date, despite considerable effort, validated small-molecule AQP4 inhibitors have not been advanced. However, a biologic ('aquaporumab') is in development for neuromyelitis optica, an autoimmune inflammatory demyelinating disease where CNS pathology is initiated by binding of anti-AQP4 autoantibodies to astrocyte AQP4.
A scheduling algorithm of LTE based on coverage of physical channels (2011)

Considering the diversity of the LTE traffic Qos and the variable channel coverage caused by the time-frequency two-dimensional structure, a reasonable scheduling algorithm is proposed to enable the coverage of queues as large and close as possible and guarantee traffic Qos. Simulation results show that the new algorithm can ensure the coverage of channels as large and close as possible, while meet all Qos requirements of traffic queues in order to achieve better network planning.
Synthesis, Characterization, and Activity in Ethylene Polymerization of Silica Supported Cationic Cyclopentadienyl Zirconium Complexes (2006)

Cp*ZrMe3 reacts with silica pretreated at 800 degrees C, SiO(2-(800)) through two pathways: (a) protolysis of a Zr-Me group by surface silanols and (b) transfer of a methyl group to the surface by opening of strained siloxane bridges, in a relative proportion of ca. 9/1, respectively, affording a well-defined surface species [([triple bond]SiO)ZrCp*(Me)2], 3, but with two different local environments 3a, [([triple bond]SiO)ZrCp*(Me)2][[triple bond]Si-O-Si[triple bond]], and the other with 3b, [structure: see text]. The reaction of the species 3 with B(C6F5)3 is controlled by this local environment and gives three surface species [([triple bond]SiO)ZrCp*(Me)](+)[MeB(C6F5)3]- [[triple bond]Si-O-Si[triple bond]], 4a (20%), [([triple bond]SiO)ZrCp*(Me)](+)[(Me)B(C6F5)3]- [[triple bond]Si-Me], 4b (10%), and [([triple bond]SiO)2ZrCp*](+)[(Me)B(C6F5)(3)](-)[[triple bond]Si-O-Si[triple bond]], 5 (70%). On the contrary, the reaction of Cp*Zr(Me)3, Cp2Zr(Me)2 with [[triple bond]SiO-B(C6F5)3](-)[HNEt2Ph]+, 6, leads to a unique species [([triple bond]SiO)B(C6F5)3](-)[Cp*Zr(Me)2.NEt2Ph]+, 7, and [([triple bond]SiO)ZrCp2](+)[(Me)B(C6F5)3]-, 9 respectively. The complexes 4 and 7 are active catalysts in ethylene polymerization at room temperature, 93 and 67 kg PE mol Zr1- atm(-1) bar(-1), respectively, indicating that covalently bounded Zr catalyst 4 is slightly more active than the "floating" cationic catalyst 7.