gebhart/patrepeval huggingface dataset:
Photoinduced Intramolecular Electron-Transfer Processes in [60]Fullerene-(Spacer)-<i>N,N</i>-Bis(biphenylyl)aniline Dyad in Solutions (2005)

Intramolecular photoinduced charge-separation and charge-recombination processes in a covalently connected C60-(spacer)-N,N-bis(biphenylyl)aniline (C60-spacer-BBA) dyad, in which the center-to-center distance of the electron acceptor and electron donor is 15 A, have been studied by time-resolved fluorescence and transient absorption methods. The observed low fluorescence intensity and the short fluorescence lifetime of the C60 moiety of the dyad in PhCN and THF indicate that charge separation takes place via the excited singlet state of the C60 moiety at a quite fast rate and a high efficiency. The nanosecond transient absorption spectra in PhCN and THF showed the broad absorption bands at 880 and 1100 nm, which were attributed to C60(*-)-spacer-BBA(*+). The charge-separated state decays with a lifetime of 330-360 ns in PhCN and THF at room temperature. From temperature dependence of the charge-recombination rate constants, the reorganization energy was evaluated to be 0.77-0.87 eV, which indicates that the charge-recombination process is in the inverted region of the Marcus parabola. With lowering temperature, the contribution of charge separation via the excited triplet state of the C60 moiety increases due to an increase in solvation of C60(*-)-spacer-BBA(*+).
A new method for the carbon-extension reactions of azetidin-2-ones at the 4-position (1980)

High yields of 4-alkyl-, 4-allyl-, 4-vinyl-, or 4-ethynyl-azetidin-2-ones are obtained by treating 4-sulphonylazetidin-2-ones with either lithium organocuprates or Grignard reagents, but yields from 4-acetoxyazetidin-2-one with Grignard reagents are low.
Near-IR spectroscopic measurement of seawater salinity (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNear-IR spectroscopic measurement of seawater salinityJie Lin and Chris W. BrownCite this: Environ. Sci. Technol. 1993, 27, 8, 1611–1615Publication Date (Print):August 1, 1993Publication History Published online1 May 2002Published inissue 1 August 1993https://pubs.acs.org/doi/10.1021/es00045a017https://doi.org/10.1021/es00045a017research-articleACS PublicationsRequest reuse permissionsArticle Views288Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Deep Learning Anomaly Detection for Cellular IoT With Applications in Smart Logistics (2021)

The number of connected Internet of Things (IoT) devices within cyber-physical infrastructure systems grows at an increasing rate. This poses significant device management and security challenges to current IoT networks. Among several approaches to cope with these challenges, data-based methods rooted in deep learning (DL) are receiving an increased interest. In this paper, motivated by the upcoming surge of 5G IoT connectivity in industrial environments, we propose to integrate a DL-based anomaly detection (AD) as a service into the 3GPP mobile cellular IoT architecture. The proposed architecture embeds autoencoder based anomaly detection modules both at the IoT devices (ADM-EDGE) and in the mobile core network (ADM-FOG), thereby balancing between the system responsiveness and accuracy. We design, integrate, demonstrate and evaluate a testbed that implements the above service in a real-world deployment integrated within the 3GPP Narrow-Band IoT (NB-IoT) mobile operator network.
Sterol Regulation of Fatty Acid Synthase Promoter (1995)

The gene encoding fatty acid synthase, the essential multi-functional enzyme of fatty acid biosynthesis, is shown to be regulated by cellular sterol levels similar to genes that encode important proteins of cholesterol metabolism. We show that expression of the endogenous FAS gene is repressed when regulatory sterols are included in the culture medium of HepG2 cells and that the FAS promoter is subject to similar regulation when fused to the luciferase reporter gene. Mutational studies demonstrate that sterol regulation is mediated by binding sites for the sterol regulatory element-binding protein (SREBP) and transcription factor Sp1, making it mechanistically similar to sterol regulation of the low density lipoprotein receptor gene. It is also demonstrated that SREBP and Sp1 synergistically activate the FAS promoter in Drosophila tissue culture cells, which lack endogenous Sp1. These experiments provide key molecular evidence that directly links the metabolism of fatty acids and cholesterol together.
Small cell carcinoma of the esophagus (1989)

Ten cases of small cell carcinoma of the esophagus were studied clinicopathologically and immunohistochemically. Seven of the ten were also examined by electron microscopy. Histologically, six were oat cell type, four the intermediate cell type, and multiple histologic sections revealed squamous and glandular differentiations in small or minute areas of seven and two tumors, respectively. In four of the six polypoid tumors, the epithelium covering the tumor showed a malignant conversion accompanied by a proliferation of small anaplastic cells. Another one showed a cribriform pattern in a small area of the tumor. Argyrophilic tumor cells were seen in six cases and tumor cells immunohistochemically positive for ACTH and calcitonin were seen in six, and three cases, respectively. Neurosecretory granules were evident in three of the seven cases examined by electron microscopy. These findings suggest that a small cell carcinoma of the esophagus differentiates toward a squamous, glandular, or neurosecretory lesion, thereby supporting the idea of a totipotential stem cell origin of this tumor. The prognosis of patients with this tumor was poor, in accord with the evidence of aggressive lymphatic and blood vessel permeation.
Class D service architecture in an ATM-Internet (2002)

This paper proposes a class D service (datagram delivery) architecture in an ATM-Internet, which is the network interconnecting ATM-LANs. The datagram delivery to the destination terminal is performed by connectionless server, so called CLS, which is located in the ATM-LAN where the destination terminal belongs. Each CLS only manages the addresses for the terminals belonging to the corresponding ATM-LAN. The cells belonging to a certain datagram are transferred through a single (seam-less) ATM connection from the source terminal to the CLS in the ATM-LAN where the destination terminal belongs. The proposed class D service architecture can be applied to the ATM-LAN system based on VPI routing architecture, easily.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Telemaintenance applications for the Wearable/sup TM/PC (2002)

This paper explores the concept of providing military maintenance personnel with a wearable personal computer and interactive electronic technical manual (IETM) support as maintenance tasks are performed at equipment sites. Wearable PCs, when combined with PCMCIA card technologies, are an evolutionary hardware concept worn on the technician's body, enabling personnel to obtain information such as specific maintenance procedures, drawings and digital photographs of the equipment and sub-assemblies. All maintenance information is provided where and when it is needed, virtually eliminating the need for any paper-based technical documentation. It is hypothesized that wearable technology will increase maintenance productivity, minimize errors, and reduce training requirements. Wearable PCs incorporate voice recognition and helmet mounted display technology allowing maintenance personnel hands and eyes free as they perform maintenance tasks. Wearable PCs also utilize Global Positioning System (GPS) receivers, high-speed fax modems, and wireless LAN technology for connectivity to to servers and the Internet system. The WEARABLE/sup TM/ PC makes the concept of "telemaintenance" a reality.
A pragmatic approach to predict hardware failures in storage systems using MPP database and big data technologies (2014)

A storage system in a data center consists of various components such as Disk Array Enclosure (DAE), disks, processors, servers, hosts running different applications, and so on. Hard disk and server failures are not frequent but are often very costly. Such failures can have a very adverse effect on the business of an organization. The ability to accurately predict an impending disk or server failure can add an essential functionality for designing a reliable, fault tolerant and continuously available storage system. This paper explains a novel approach to predict hardware failures using spectrum-kernel Parallel Support Vector Machine (Parallel SVM) method by analyzing the system events logged in the system log files. These log files not only records the events processed by the system but it also holds the messages as the system state changes. A single message in the system log file is insufficient for any prediction and such prediction is bound to be less accurate. The approach introduced in the paper uses a sequence or pattern of messages from the system log file using a Sliding Window of messages with window size of 5 message sequence to predict the likelihood of a failure. These Sliding Windows of message sequences acts as inputs to the Parallel SVM. The Parallel SVM further tags the messages to a failure or non-failure system. Data Mining techniques are used in extracting useful information from the raw dataset. A solutioning model is developed using the structured dataset and Machine Learning algorithms. This environment when implemented using actual system logs from Linux-based storage system have shown to predict a hardware failure with accuracy of 90-92 percent.
Low Circulating Folate and Vitamin B <sub>6</sub> Concentrations (1998)

Lower levels of folate and vitamin B6 confer an increased risk of atherosclerosis. Clinical trials are now required to evaluate the effect of treatment with these vitamins in the primary and secondary prevention of vascular diseases.
Lay Students and the Kakdlg of Written Verracolar Narrative: an Inventory of Tun-huang Mahuscripts (1981)

(1981). Lay Students and the Kakdlg of Written Verracolar Narrative: an Inventory of Tun-huang Mahuscripts. CHINOPERL: Vol. 10, No. 1, pp. 5-96.
Initial Studies of Protein Nanotube Oligomerization from a Modified Gold Surface (2009)

The type IV pilus of Pseudomonas aeruginosa is a nanofibre composed of multiple copies of a single protein subunit, the type IV pilin. In the presence of a hydrophobic surface or solution, engineered pilin monomers oligomerize into soluble, high molecular weight structures—protein nanotubes (PNTs). P. aeruginosa pilins, pili and pilin-derived PNTs have been shown to bind both biotic surfaces (cells) as well as abiotic surfaces such as stainless steel. Specific binding of PNTs to abiotic surfaces has the potential for the development of novel biometallic interfaces, leading to possible applications such as biomolecular probes and nanoelectronics. In the current report, we discuss our initial findings on growth of PNTs directly from a decanethiol functionalized gold surface. Utilizing atomic force microscopy, PNTs oligomerized from surface constrained alkylthiols were observed to be several micrometers in length with an average diameter of 36 ± 3 nm. In comparison with reported values for the diameter of native type IV pili and PNTs in solution (∼6 nm), the average observed diameter of surface oligomerized PNTs suggests a multiple PNT clustered filament on the gold surface.
Variance reduction using interframe coherence for animated scenes (2015)

In an animated scene, geometry and lighting often change in an unpredictable way. Rendering algorithms based on Monte Carlo methods are usually employed to precisely capture all features of an animated scene. However, Monte Carlo methods typically take a long time to produce a noise-free image. In this paper, we propose a variance reduction technique for Monte Carlo methods which exploits coherence between frames. Firstly, we introduce a dual cone model to measure the incident coherence intersecting camera rays in object space. Secondly, we allocate multiple frame buffers to store image samples from consecutive frames. Finally, the color of a pixel in one frame is computed by borrowing samples from neighboring pixels in current, previous, and subsequent frames. Our experiments show that noise is greatly reduced by our method since the number of effective samples is increased by use of borrowed samples.
[Aminooxypropylamine--an effective inhibitor of ornithine decarboxylase in vitro and in vivo]. (1985)

Hydroxylamine-containing analogues of putrescine and cadaverine have been found effective in inhibiting the mouse liver ornithine decarboxylase, the best among synthesized were 1-aminooxy-3-aminopropane (I50 2.10(-8) M) and 1-aminooxy-4-aminobutane (I50 2.10(-7) M). The inhibitory effect of these substances on the mouse liver ornithine-transaminase and S-adenosylmethionine decarboxylase from E. coli was displayed at concentrations higher by several orders of magnitude, that demonstrated the specificity of the compounds of this type. 1-Aminooxy-3-aminopropane in experiments in vivo suppressed the ornithine decarboxylase activity in mouse liver at 16 mg/kg by 75%, the toxic effect being insignificant.
Assignments of Carbon NMR Resonances for Microcrystalline Ubiquitin (2004)

Solid-state NMR 2D spectroscopy was used to correlate carbon backbone and side-chain chemical shifts for uniformly (13)C,(15)N-enriched microcrystalline ubiquitin. High applied field strengths, 800 MHz for protons, moderate proton decoupling fields, 80-100 kHz, and high magic angle sample spinning frequencies, 20 kHz, were used to narrow the most of the carbon line widths to 0.5-0.8 ppm. Homonuclear magnetization transfer was effected by matching the proton RF field to the spinning frequency, the so-called dipolar-assisted rotational resonance (DARR) (Takegoshi, K.; Nakamura, S.; Terao, T. Chem. Phys. Lett. 2001, 344, 631-637), and a mixing time of 20 ms was used to maximize the intensity of one-bond transfers between carbon atoms. This polarization transfer sequence resulted in roughly 14% transfer efficiencies for directly bonded carbon pairs and 4% transfer efficiencies for carbons separated by a third carbon. With this simple procedure, the majority of the one-bond correlations was observed with moderate transfer efficiencies, and many two-bond correlations were also observed with weaker intensities. Spin systems could be identified for more than half of the amino acid side chains, and site-specific assignments were readily possible via comparison with 400 MHz (15)N-(13)C-(13)C correlation spectroscopy (described separately).
Alzheimer's disease: cognitive and behavioral pharmacotherapy. (1997)

Alzheimer's disease is a progressive degenerative disease with cognitive and behavioral manifestations. The pathophysiology of Alzheimer's disease is increasingly well understood, leading to approved and experimental therapies. Mutations on chromosomes 1, 14, and 21 can cause the disease and are sometimes present in patients with early onset Alzheimer's disease. Older patients--comprising the majority of Alzheimer's disease victims--have a variety of risk factors including age, gender, history of head trauma, low education level, and apolipoprotein genotype. The pathogenetic process leads to regional cell loss and biochemical deficits. The mutations and risk factors lead to increased amyloid production or accumulation and nerve cell death. Neurons atrophy in the cerebral cortex and in source nuclei of important neurotransmitters. The deficiency of acetylcholine can be partially remedied by cholinesterase inhibitors that produce modest cognitive and behavioral improvement. Anti-amyloid agents, antioxidants, anti-inflammatory drugs, estrogens, and calcium channel blockers may all slow the progression of Alzheimer's disease by interfering with specific steps within the disease cascade. Neuropsychiatric symptoms are also common in Alzheimer's disease and may be ameliorated by conventional psychotropic agents. Clinicians can currently offer substantial help to Alzheimer's disease patients, and the future promises more effective pharmacotherapy.
Amino Acid Determinants in Cyclooxygenase-2 Oxygenation of the Endocannabinoid 2-Arachidonylglycerol (2001)

The endocannabinoid, 2-arachidonylglycerol (2-AG), is an endogenous ligand for the central (CB1) and peripheral (CB2) cannabinoid receptors and has been shown to be efficiently and selectively oxygenated by cyclooxygenase (COX)-2. We have investigated 2-AG/COX-2 interactions through site-directed mutagenesis. An evaluation of more than 20 site-directed mutants of murine COX-2 has allowed for the development of a model of 2-AG binding within the COX-2 active site. Most strikingly, these studies have identified Arg-513 as a critical determinant in the ability of COX-2 to efficiently generate prostaglandin H(2) glycerol ester, explaining, in part, the observed isoform selectivity for this substrate. Mutational analysis of Leu-531, an amino acid located directly across from Arg-513 in the COX-2 active site, suggests that 2-AG is shifted in the active site away from this hydrophobic residue and toward Arg-513 relative to arachidonic acid. Despite this difference, aspirin-treated COX-2 oxygenates 2-AG to afford 15-hydroxyeicosatetraenoic acid glycerol ester in a reaction analogous to the C-15 oxygenation of arachidonic acid observed with acetylated COX-2. Finally, the differences in substrate binding do not alter the stereospecificity of the cyclooxygenase reaction; 2-AG-derived and arachidonic acid-derived products share identical stereochemistry.
Consistent 2-D phase unwrapping guided by a quality map (2002)

The problem of 2D phase unwrapping arises when a spatially varying quantity is measured module some period. One needs to reconstruct a smooth unwrapped phase, consistent with the original data, by adding a multiple of the period to each sample. Smoothness typically cannot be enforced over all of the scene, due to noise and localized jumps. An unwrapping algorithm may form a mask within which phase discontinuities are allowed. In interferometry a quality map is available, indicating the reliability of the measurements. In this case, the mask should be contained as much as possible in areas of low quality. This paper presents an algorithm for phase unwrapping in which the mask design is guided by the quality map. The mask is grown from the residues (as defined by Goldstein et al.) into areas where the quality is below a threshold. A connected component of the mask stops growing when its residue charge becomes balanced. The threshold is raised as necessary to allow growth. This stage terminates when all components are balanced. The mask is then thinned by removing points that are not needed to cover the residues correctly. The unwrapped phase is found by simple 1D unwrapping along paths that avoid the mask. The authors present an example solution found by the algorithm and discuss possible modifications.
The sympathetic nervous system and obstructive sleep apnea (1997)

Patients with obstructive sleep apnea experience repetitive apneic events during sleep, with consequent hypoxia and hypercapnia. Hypoxia and hypercapnia, acting via the chemoreflexes, elicit increases in sympathetic nerve activity. The sympathetic responses to hypoxia and hypercapnia are potentiated during apnea, when the sympathetic inhibitory influence of the thoracic afferent nerves is eliminated. As a consequence of the sympathetic vasoconstrictor response to apneic events, patients with obstructive sleep apnea manifest marked increases in blood pressure during sleep, especially evident at the end of the apnea. The increases in sympathetic activity and blood pressure during sleep in these patients appear to carry over into the daytime such that patients with sleep apnea have an increased prevalence of hypertension and high levels of sympathetic nerve activity. Although the mechanism underlying the persistent elevation in sympathetic activity during the daytime is not known, it is likely that the increased sympathetic drive is implicated in the higher daytime blood pressures in these patients. Whereas patients with sleep apnea have an increased prevalence of hypertension, in those patients with sleep apnea who do have hypertension, the sympathetic response to apneic events may be potentiated. This may be secondary to impaired baroreflex sensitivity, since the baroreflexes exert an inhibitory influence on the chemoreflex responses to hypoxia. Treatment with continuous positive airway pressure results in an acute reduction in blood pressure and sympathetic activity during sleep. Prolonged effective treatment of sleep apnea may also reduce daytime blood pressure levels. This review examines the physiology of the chemoreflex responses to hypoxia, hypercapnia and apnea, as well as the physiologic responses to sleep in normal humans. These physiologic responses are compared with the pathophysiologic sympathetic and hemodynamic responses that characterize obstructive sleep apnea. Increases in sympathetic activity and blood pressure in patients with obstructive sleep apnea may play a role in linking sleep apnea to hypertension and cardiac and vascular events.
Low-loss distributed MEMS phase shifter (2000)

This letter presents a one-bit low-loss K/K/sub a/-band phase shifter circuit that employs microelectromechanical systems (MEMS) capacitors. The measured results demonstrate a delay line with a 180/spl deg/ phase shift/1.l7 dB loss phase shift at 25 GHz, 270/spl deg/ phase shift/1.69 dB loss at 35 GHz, and a return loss better than 11 dB over a 0-35-GHz band. The state-of-the-art insertion loss performance, 154/spl deg//dB at 25 GHz and 160/spl deg//dB at 35 GHz, demonstrates the potential for the implementation of a very low-loss multibit digital MEMS phase shifter.