gebhart/patrepeval huggingface dataset:
Selection and characterization of monoclonal antibodies to the idiotype‐like structure of an interleukin‐2‐producing human leukemia t‐cell line (1985)

A variant of the Jurkat leukemia cell line termed JA3 (surface phenotype: T11+., T3+, T4-, T8-, T6-, T1+, 3A1+, HLA-DR-, Tac-, 4F2+) has been used for mouse immunization and production of monoclonal antibodies (MAbs) to molecules carrying clonotypic determinants that are thought to serve as receptor for antigen on human T cells. JA3 had been selected because of its ability to release large amounts of IL-2 following stimulation with phytohemagglutinin (PHA) or anti-T3 antibody in the presence of phorbolmyristate acetate (PMA). This functional property has been exploited for screening of MAbs potentially directed to idiotype-like structures of JA3 cells. Thus supernatants of hybridomas (obtained by fusing mouse splenocytes with P3-UI myeloma cells) were analyzed for their ability to induce JA3 cells to release IL-2 in the presence of PMA. Four stimulatory antibodies reacted with JA3 but not with polyclonal T-cell populations, T-cell clones, or T and B tumor cell lines as assessed by indirect immunofluorescence and fluorescence-activated cell sorter (FACS) analysis. All 4 antibodies immunoprecipitated the same disulphide-linked heterodimeric molecules having a molecular mass (Mr) of approximately 85,000 under non-reducing conditions that was resolved in 2 major peptides of 40,000 and 45,000 under reducing conditions. These data indicate that these antibodies (termed anti-JTi) were directed to the clonotypic-restricted structures of the JA3 T-cell-receptor molecules. Unlike the anticlonotypic antibodies described so far, anti-JTi MAbs were capable of triggering IL-2 production even in unbound, soluble form, in the absence of adherent cells or PMA. Competitive inhibition experiments, in which 35S-labelled anti-JTi MAbs have been used, provided evidence that they may be directed against different epitopes on the same clonotypic structure.
West Side News March 16, 1889 (1889)

West Side News was a weekly newspaper published by the Wright Brothers. This paper, published in March 1889 through May of 1890, featured news from the west side of Dayton. The front page of this issue features a letter to the editor asking West Side natives to patronize businesses on the West Side, an uprising and escape from a local work house, and more. This is the first issue of the second volume of the West Side News. On the second page they post their mission statement as being "to present to our readers a paper worthy of the city and people whom it is intended to represent..." Also included in this issue are national news, local news, humorous stories, and advertisements.
Vacuum arc ion and plasma source Raduga 5 for materials treatment (1998)

This article describes a new modification of high current ion and plasma source Raduga 5. A dc vacuum arc is used to generate plasma. Generation of accelerated ion beams is realized in the Raduga 5 in a repetitively pulsed mode with the pulse repetition rate up to 200 pps, the pulse duration up to 400 μs and the accelerating voltage up to 50 kV. To clean the vacuum arc plasma from the microparticle fraction of the products of the explosive cathode emission of the arc evaporator a new version of a straight-line plasma filter is used. This article describes a new version of the accelerating diode which works under conditions of high thermal loads with a continuous metal plasma flow and repetitively pulsed formation of an accelerated ion beams. A simultaneous generation of a metal plasma flow and pulse beams of accelerated ions in the Raduga 5 source ensures realization of the technologies of an ion assisted metal plasma deposition, ion implantation under ion sputtering compensation by metal plasma deposition and ion implantation. The experimental data on different technological regimes of the source are presented in this article. Potential areas of the perspective application of the ion and plasma source Raduga 5 of ion and ion-plasma treatment of different materials are discussed.
A code coverage-based test suite reduction and prioritization framework (2014)

Software testing is extensively used to ensure the development of a quality software system. The test suite size tends to increase by including new test cases due to software evolution. Consequently, the entire test suite cannot be executed considering budget and time limitations. Researchers have examined test suite reduction and prioritization techniques to address the test suite size problem. However, combination of these techniques can be useful for various regression testing situations. In this paper, we present a new code coverage-based test suite reduction and prioritization framework called TestOptimizer. The framework performs a suitable combination of TestFilter and St-Total techniques to determine optimal test cases, keeping in view of time restrictions. The performance of the proposed framework has been assessed using a case study. Results show that TestOptimizer can be beneficial to solve the test suite size problem within time constraints and has a profound impact on the required cost and effort of regression testing.
Fourier-transform infrared spectra of organic compounds in solution and as thin layers obtained by using an attenuated total internal reflectance fiber-optic cell (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFourier-transform infrared spectra of organic compounds in solution and as thin layers obtained by using an attenuated total internal reflectance fiber-optic cellShimon. Simhony, Abraham. Katzir, and Edward M. KosowerCite this: Anal. Chem. 1988, 60, 18, 1908–1910Publication Date (Print):September 15, 1988Publication History Published online1 May 2002Published inissue 15 September 1988https://pubs.acs.org/doi/10.1021/ac00169a013https://doi.org/10.1021/ac00169a013research-articleACS PublicationsRequest reuse permissionsArticle Views211Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Redox potentials and electronic structures of organic complexes of ruthenium and rhodium (1993)

The redox properties of mononuclear and polynuclear rhodium and ruthenium complexes are examined. Attention is concentrated on the possible locations of the electronic changes in the redox transitions. The relation between the electrochemical parameters of the complexes and electronic spectroscopic data is traced. Extensive reference data are presented on the oxidation and reduction potentials of mononuclear and polynuclear rhodium and ruthenium complexes. The bibliography includes133 references.
Selective carbon dioxide adsorption of ε-Keggin-type zincomolybdate-based purely inorganic 3D frameworks (2014)

The new ε-Keggin POM-based frameworks effectively separate CO<sub>2</sub> from a CO<sub>2</sub>/CH<sub>4</sub> mixture.
FeTaN/IrMn exchange-coupled multilayer films as soft underlayers for perpendicular media (2001)

Soft underlayers of FeTaN/IrMn exchange-coupled films for perpendicular media have been investigated. FeTaN(t/sub FeTaN/)/IrMn (10 nm) multilayer films having different FeTaN thicknesses t/sub FeTaN/ from 20 nm to 200 nm were prepared while keeping the total FeTaN thickness at 200 nm. When t/sub FeTnN/ decreased below 100 nm to 20 mn, the exchange bias field increased from 3.6 Oe to 77 Oe, and the pinning field from 25 Oe to 105 Oe. The interfacial exchange energy, J, was 0.10/spl sim/0.13 ergs/cm/sup 2/. As the exchange bias field increased, the angular reversibility increased from 10/spl deg/ to 57/spl deg/ in good agreement with the coherent rotational model. Radially oriented multilayer films of FeTaN (20 nm)/[IrMn(10 nm)/FeTaN(20 nm)]/sub 9/ were successfully prepared on 65 mm disks and showed excellent angular reversibility, a pinning field >70 Oe, and a permeability of 70 up to 2 GHz.
Fundamentals of mathematical logic (2006)

This introductory graduate text covers modern mathematical logic from propositional, first-order and infinitary logic and Godel's Incompleteness Theorems to extensive introductions to set theory, model theory and recursion (computability) theory. Based on the author's more than 35 years of teaching experience, the book develops students' intuition by presenting complex ideas in the simplest context for which they make sense. The book is appropriate for use as a classroom text, for self-study, and as a reference on the state of modern logic.
Defective Phagocytosis of Isolated Rod Outer Segments by RCS Rat Retinal Pigment Epithelium in Culture (1977)

Retinal pigment epithelium cultured from normal rats phagocytizes large amounts of rod outer segment fragments isolated from normal rats and from RCS rats with inherited retinal degeneration. Cultured RCS rat pigment epithelium rarely ingests outer segment material, although the cells extend cellular processes around fragments of either type. Both normal and RCS pigment epithelium phagocytize polystyrene spheres. This demonstrates that RCS rat pigment epithelial cells contain a defect in the mechanism for phagocytizing outer segments.
Strongly Luminescent Palladium(0) and Platinum(0) Diphosphine Complexes (2007)

The synthesis, structure, and photoluminescence of palladium(0) and platinum(0) complexes containing biarydiphosphines, biphep (biphep = 2,2'-bis(diphenylphosphino)-1,1'-biphenyl) and binap (binap = 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl) have been studied. X-ray structure analysis of [Pt(biphep)(2)] revealed the distorted-tetrahedral geometry of the complex. The photophysical properties of the three complexes [Pd(biphep)(2)], [Pt(biphep)(2)], and [Pd(binap)(2)] were investigated and compared with that of the previously reported [Pt(binap)(2)] complex. The [Pd(biphep)(2)] complex shows the strongest luminescence with a high quantum yield (38%) and a long lifetime (3.2 micros) in a toluene solution at room temperature. The luminescence should be due to metal-to-ligand charge transfer excited states. At room temperature, radiative rate constants of the four complexes show similar values. The difference in the luminescent properties should reflect the different nonradiative rate constants of the complexes. The temperature-dependence of the luminescence spectra and lifetime of the complexes were also discussed.
Herpes simplex virus type 1 mediates fusion through a hemifusion intermediate by sequential activity of glycoproteins D, H, L, and B (2007)

Virus-induced membrane fusion can be subdivided into three phases defined by studies of class I and class II fusion proteins. During Phase I, two membranes are brought into close apposition. Phase II marks the mixing of the outer membrane leaflets leading to formation of a hemifusion intermediate. A fusion pore stably forms and expands in Phase III, thereby completing the fusion process. Herpes simplex virus type 1 (HSV-1) requires four glycoproteins to complete membrane fusion, but none has been defined as class I or II. Therefore, we investigated whether HSV-1-induced membrane fusion occurred following the same general phases as those described for class I and II proteins. In this study we demonstrate that glycoprotein D (gD) and the glycoprotein H and glycoprotein L complex (gHL) mediated lipid mixing indicative of hemifusion. However, content mixing and full fusion required glycoprotein B (gB) to be present along with gD and gHL. Our results indicate that, like class I and II fusion proteins, fusion mediated by HSV-1 glycoproteins occurred through a hemifusion intermediate. In addition, both gB and gHL are probably directly involved in the fusion process. From this, we propose a sequential model for fusion via HSV-1 glycoproteins whereby gD is required for Phase I, gHL is required for Phase II, and gB is required for Phase III. We further propose that glycoprotein H and gB are likely to function sequentially to promote membrane fusion in other herpesviruses such as Epstein-Barr virus and human herpesvirus 8.
.beta.-Hydride Elimination and Regioselectivity in the Rhodium-Catalyzed Hydroformylation of Open Chain Unsaturated Ethers (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT.beta.-Hydride Elimination and Regioselectivity in the Rhodium-Catalyzed Hydroformylation of Open Chain Unsaturated EthersRaffaello Lazzaroni, Roberta Settambolo, and Gloria Uccello-BarrettaCite this: Organometallics 1995, 14, 10, 4644–4650Publication Date (Print):October 1, 1995Publication History Published online1 May 2002Published inissue 1 October 1995https://pubs.acs.org/doi/10.1021/om00010a031https://doi.org/10.1021/om00010a031research-articleACS PublicationsRequest reuse permissionsArticle Views263Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A new algorithm for 3D surface matching (2004)

A new algorithm for least squares matching of overlapping 3D surfaces, digitized/sampled point by point using a laser scanner device, the photogrammetric method or other techniques, is proposed. In photogrammetry, the problem statement of surface patch matching and its solution method was first addressed by Gruen (1985a) as a straight application of Least Squares Matching. There have been some studies on the absolute orientation of stereo models using DEMs as control information. These works have been known as DEM matching. Furthermore, techniques for 2.5D DEM surface matching have been developed, which correspond mathematically with least squares image matching. 2.5D surfaces have limited value, especially in close range applications. Our proposed method estimates the transformation parameters between two or more fully 3D surface patches, minimizing the Euclidean distances instead of Z-differences between the surfaces by least squares. This formulation gives the opportunity of matching arbitrarily oriented surface patches. An observation equation is written for each surface element on the template surface patch, i.e. for each sampled point. The geometric relationship between the conjugate surface patches is defined as a 7-parameter 3D similarity transformation. The Least Squares observations of the adjustment are defined by the observation vector whose elements are Euclidean distances between the template and search surface elements. The unknown transformation parameters are treated as stochastic quantities using proper weights. This extension of the functional model gives control over the estimation parameters. The details of the mathematical modelling of the proposed method, the convergence behavior, and statistical analysis of the theoretical precision of the estimated parameters are explained. Furthermore, some experimental results based on registration of close-range laser scanner and photogrammetric point clouds are presented. This new surface matching technique derives its mathematical strength from the least squares image matching concept and offers high level flexibility for any kind of 3D surface correspondence problem, as well as statistical tools for the analysis of the quality of the final results.
Human Conjunctivitis (1976)

One hundred forty-three patients (207 eyes) with conjunctivitis or blepharoconjunctivitis were studied. Attempts were made to establish an etiologic diagnosis by clinical and laboratory methods. The etiologic diagnosis that was made on the basis of the initial clinical examination correlated poorly with the results of standard laboratory tests. Conversely, the standard laboratory evaluation failed to establish a definitive diagnosis in the majority of cases. These findings suggest that the diagnostic dogmatism prevalent in conjunctivitis is unwarranted. Morphologic signs and routine laboratory tests leave us without a verified etiologic diagnosis in a substantial number of cases.¿
Histone H2AX Phosphorylation after Cell Irradiation with UV-B: Relationship to Cell Cycle Phase and Induction of Apoptosis (2004)

Damage to DNA that engenders double-strand breaks (DSBs) triggers phosphorylation of histone H2AX on Ser-139. Expression of phosphorylated H2AX (gammaH2AX) can be revealed immunocytochemically; the intensity of gammaH2AX immunofluorescence (IF) measured by cytometry was reported to correlate with the frequency of DSBs induced by X-ray radiation or by DNA damaging antitumor drugs. The aim of the present study was to measure expression of gammaH2AX following exposure of HeLa and HL-60 cells to a wide range of doses of UV-B light (6.1 J/m(2)-3.45 kJ/m(2)) and using multiparameter flow and laser scanning cytometry (LSC) to correlate DNA damage with cell cycle phase and induction of apoptosis. In both cell lines, the highest degree of H2AX phosphorylation induced by UV was seen in S-phase cells, particularly during early portion of S. In cells that did not replicate DNA (G(1), G(2) and M) the degree of H2AX phosphorylation was markedly lower than that in S-phase cells, and was strongly UV dose-dependent. Furthermore, the level of UV-induced gammaH2AX in G(1), G(2) and M was much higher in HeLa- than in HL-60- cells. Apoptotic cells become apparent >2h after exposure to UV and exhibited nearly an order of magnitude higher intensity of gammaH2AX IF than that initially induced by UV; predominantly S-phase cells underwent apoptosis. While the suppression of DNA replication, by aphidicolin prevented the induction of H2AX phosphorylation by UV in most S phase cells, it had no effect on a small cohort of cells that appeared to be entering S-phase, that expressed very high levels of gammaH2AX. Furthermore, aphidicolin itself induced gammaH2AX in early-S phase cells. The induction of gammaH2AX by UV was inhibited, but the incidence of apoptosis increased, by 5 mM caffeine, a known inhibitor of PI-3-related kinases. The data are consistent with the notion that H2AX phosphorylation observed throughout S phase reflects formation of DSBs due to the collision of replication forks with the UV-induced primary DNA lesions. Induction of gammaH2AX in G(1), G(2) and M is likely a response to the primary DSBs generated during UV exposure and/or DNA repair. It is unclear why the latter process was more pronounced in HeLa than in HL-60 cells.
Anodic Protection off Austenitic Stainless Steels In Sulfuric Acid-Chloride Media (1962)

Anodic polarization measurements show that chloride additions up to 0.1 normality do not seriously affect the passive or transpassive dissolution behavior of austenitic stainless steels in sulfuric acid. However, the primary potential for passivation is shifted to more noble values and the critical current for passivation is greatly increased. Stress-corrosion cracking, which occurs at room temperature in 10 normal sulfuric acid with 0.5 normal sodium chloride, is not observed under anodic protection. Hence, anodic protection not only decreases general corrosion but prevents stress-corrosion cracking. 3.8.3
Chorionic villi sampling with an echogenic catheter: experiences of the first 500 cases (1987)

Using a newly developed CVS catheter with enhanced echogenicity we performed CVS in 501 consecutive cases. The abortion rate of 4.3% prior to 28 weeks of gestation in this series is within the background rate of controls matched for maternal age. The loss rate was clearly correlated to the number of insertions, time of sampling and sampling success. CVS is safest between 9 and 11 weeks of pregnancy. We recommend to restrict the number of insertions to a maximum of 3. The rate of failed samplings was 4, reflecting a low "aggressiveness in seeking a sample". Complete follow-up of 259 consecutive cases gave no indication of an increased rate of congenital anomalies following CVS in early pregnancy. In our study we also performed cervical swabs, pregnancy hormone testing, maternal serum AFP determination prior to and after CVS as well as maternal AFP screening at 16 weeks of pregnancy together with a detailed sonographic examination. We conclude that CVS can be considered now a safe and reliable diagnostic procedure, but requires further detailed documentation and close follow-up in controlled trials.
Determination of a non-volatile nitrosamine by using denitrosation and a chemiluminescence analyser (1976)

A method has been devised for the determination of N-nitrososarcosine, representative of the group of non-volatile nitrosamines of physiological origin, whereby the nitrosamine is denitrosated with hydrogen bromide to form the volatile nitrosyl bromide. After dehalogenation in a heated converter, the nitrosamine can be determined as nitric oxide by using a chemiluminescence analyser, the response being linear up to at least 200 µg. The limit of detection is below 6 ng, and is therefore much lower than that for the determination of N-nitrososarcosine as inorganic nitrite in solution after denitrosation. A response is also obtained from inorganic nitrite but this can be differentiated from that of N-nitrososarcosine by the use of acetic acid alone, prior to denitrosation with hydrogen bromide in the same solvent.
Feasibility of a Composite of Sic Whiskers in an MoSi <sub>2</sub> Matrix (1985)

A composite consisting of 20 vol% Sic whiskers in a hot‐pressed MoSi 2 matrix was investigated. The composite displayed an ∼100% increase inflexural strength and a 54% improvement in fracture toughness, compared to the values measured for the matrix material. The improvements are attributed to the change in the micro‐structure of the MoSi 2 afforded by the presence of the whiskers.