gebhart/patrepeval huggingface dataset:
NFC Internal: An Indoor Navigation System (2015)

Indoor navigation systems have recently become a popular research field due to the lack of GPS signals indoors. Several indoors navigation systems have already been proposed in order to eliminate deficiencies; however each of them has several technical and usability limitations. In this study, we propose NFC Internal, a Near Field Communication (NFC)-based indoor navigation system, which enables users to navigate through a building or a complex by enabling a simple location update, simply by touching NFC tags those are spread around and orient users to the destination. In this paper, we initially present the system requirements, give the design details and study the viability of NFC Internal with a prototype application and a case study. Moreover, we evaluate the performance of the system and compare it with existing indoor navigation systems. It is seen that NFC Internal has considerable advantages and significant contributions to existing indoor navigation systems in terms of security and privacy, cost, performance, robustness, complexity, user preference and commercial availability.
An antiresonant Fabry-Perot saturable absorber for passive mode-locking fabricated by metal-organic vapor phase epitaxy and ion implantation design, characterization, and mode-locking (1998)

We have fabricated GaAs-based antiresonant Fabry-Perot saturable absorbers (A-FPSAs) for passive mode-locking near infrared solid-state lasers using metal-organic vapor phase epitaxy (MOVPE) growth followed by ion implantation and optional thermal annealing. We present differential reflectivity measurements showing the effect of ion implantation and annealing. The devices were characterized for their large-signal response including saturation fluence, modulation depth, and nonbleachable losses-important parameters for passive mode-locking. Finally, we demonstrate mode-locking using our samples within a Ti:sapphire laser observing stable and reliable self-starting, pulses in the 100-fs range, and 50-nm tunability. Results of computer simulations are in good agreement with the experiments.
Protease-Activated Receptor-2 Stimulates Angiogenesis and Accelerates Hemodynamic Recovery in a Mouse Model of Hindlimb Ischemia (2002)

Proteinase-activated receptors (PAR-2) are expressed by the cardiovascular system and mediate vasodilation, plasma protein extravasation, and endothelial cell proliferation, all regarded as essential steps for neovascularization. We investigated the angiogenic action of PAR-2 signaling in vivo. The effect of the PAR-2 activating peptide (PAR-2AP, SLIGRL-NH2) was assessed in the absence of ischemia, and the therapeutic potential of PAR-2AP and the PAR-2 agonist trypsin (at 300 and 1.5 nmol IM daily for 21 days, respectively) was also tested in mice subjected to unilateral limb ischemia. PAR-2AP increased capillarity in normoperfused adductor skeletal muscles, whereas neither the vehicle of the PAR2-AP nor the PAR-2 reverse peptide (PAR-2RP, LRGILS-NH2) did produce any effect. In addition, both PAR-2AP and trypsin enhanced reparative angiogenic response to limb ischemia, an effect that was not produced by PAR-2RP or the vehicle of PAR-2 agonists. Potentiation of reparative angiogenesis by PAR-2AP or trypsin resulted in an accelerated hemodynamic recovery and enhanced limb salvage. In conclusions, our study is the first to demonstrate the angiogenic potential of PAR-2 stimulation in vivo. If similar effects occur in humans, PAR-2AP agonists could have some therapeutic potential for the treatment of tissue ischemia.
Interleaving temporal planning and execution in robotics domains (2004)

Many autonomous systems such as mobile robots, UAVs or spacecraft, have limited resource capacities and move in dynamic environments. Performing on-board mission plan-ning and execution in such a context requires deliberative capabilities to generate plans achieving mission goals while respecting deadlines and resource constraints, as well as run-time plan adaption mechanisms during execution. In this paper we propose a framework to integrate deliberative planning, plan repair and execution control in a dynamic environment with stringent temporal constraints. It is based on lifted partial order temporal planning techniques which produce flexible plans and allow, under certain conditions discussed in the paper, plan repair interleaved with plan ex-ecution. This framework has been implemented using the IXTET planner and used to control a robotic platform.
Relationship between Altered Na+–K+ Cotransport and Na+–Li+ Countertransport in the Erythrocytes of ‘essential’ Hypertensive Patients (1981)

1. The maximal rate of activity of sodium extrusion by the sodium pump, Na+--K+ outward cotransport, passive permeability to sodium and potassium, Na+--Li+ countertransport, and passive permeability to lithium were measured in 45 essential hypertensive patients, 24 young normotensive subjects with at least one hypertensive parent and 24 normotensive subjects with both parents normotensive. 2. The maximal rate of activity of the sodium pump and the rate constants for passive permeability to sodium, potassium and lithium were similar in the three groups. 3. The mean value for Na+--K+ outward cotransport was significantly lower and that for Na+--Li+ countertransport significantly higher in the hypertensive patients than in the normotensive subjects without a family history of hypertension, but there was a great overlap between individual values. The offspring of hypertensive parents had intermediate values. 4. A highly significant positive correlation existed between Na+--K+ cotransport and Na+--Li+ countertransport both in the normotensive and in the hypertensive subjects, indicating that in the latter there were some with high Na+--Li+ countertransport and others with low Na+--K+ cotransport. 5. In nine hypertensive families studied, if an alteration of the transport system was detected in a hypertensive propositus, the same type of alteration was also found in his still normotensive offspring, thus indicating a familial tendency for the alteration to occur.
Effect of Plasticization on Ionic Conductivity Enhancement in Relation to Glass Transition Temperature of Crosslinked Polymer Electrolyte Membranes (2016)

The relationship between glass transition (Tg) and ionic conductivity (σ) of an amorphous crosslinked polymer electrolyte membrane (PEM) was examined based on ion–dipole complexation between dissociated lithium cations and ether oxygen of poly(ethylene glycol diacrylate) and plasticization by succinonitrile (SCN). In a binary PEM consisting of a lithium salt/polymer network, Tg increased due to a strong ion–dipole interaction, whereas σ declined due to lower ion mobility coupled to reduced chain mobility. Above the threshold salt concentration of 7 mol %, dual loss tangent peaks were observed in dynamic mechanical studies, which may be ascribed to segmental relaxations of ion–dipole complexed networks and that of polymer chains surrounding the undissociated lithium salt acting like “fillers”. Upon SCN plasticization, these two peaks merged into one that was further suppressed below Tg of the pure network, whereas σ improved to the superionic conductor level. The role of plasticization on the ionic conductivity enhancement is discussed.
Laser-Frequency Stabilization Based on Steady-State Spectral-Hole Burning in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow><mml:mi>Eu</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn><mml:mo>+</mml:mo></mml:mrow></mml:msup><mml:mo>∶</mml:mo><mml:msub><mml:mrow><mml:mi mathvariant="normal">Y</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi>SiO</mml:mi></mml:mrow><mml:mrow><mml:mn>5</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (2015)

We present and analyze a method of laser-frequency stabilization via steady-state patterns of spectral holes in Eu(3+)∶Y(2)SiO(5). Three regions of spectral holes are created, spaced in frequency by the ground-state hyperfine splittings of (151)Eu(3+). The absorption pattern is shown not to degrade after days of laser-frequency stabilization. An optical frequency comparison of a laser locked to such a steady-state spectral-hole pattern with an independent cavity-stabilized laser and a Yb optical lattice clock demonstrates a spectral-hole fractional frequency instability of 1.0×10(-15)τ(-1/2) that averages to 8.5(-1.8)(+4.8)×10(-17) at τ=73 s. Residual amplitude modulation at the frequency of the rf drive applied to the fiber-coupled electro-optic modulator is reduced to less than 1×10(-6) fractional amplitude modulation at τ>1 s by an active servo. The contribution of residual amplitude modulation to the laser-frequency instability is further reduced by digital division of the transmission and incident photodetector signals to less than 1×10(-16) at τ>1 s.
Automated support for external consistency (2002)

Two models are presented of how to achieve an external-consistency objective motivated by the enterprise integrity of D.D. Clark and D.R. Wilson. The authors' notion of external consistency deals with the correctness of both assertions-propositions claimed to be true by their source-and requests-commands, authorizations, and similar sentences intended to change their source's environment. Each model considers assertions and requests from the perspective of both users and the automated system; this gives rise to defined responsibilities and requirements for both. The first, simple model assumes that users can reliably provide correct inputs to the automated system. The second model, taking a more realistic view of human enterprises, assumed that only experienced users have such capabilities. In both cases, the primary requirement imposed on the automated system is that it produces correct outputs provided enough of its inputs are correct. The authors call this an 'output warranty' requirement in reference to the vendor's responsibility for the quality of the automated system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Identification of baculovirus gene that promotes Autographa californica nuclear polyhedrosis virus replication in a nonpermissive insect cell line (1996)

A gene that promotes Autographa californica M nuclear polyhedrosis virus (AcMNPV) replication in IPLB-Ld652Y cells, a cell line that is nonpermissive for AcMNPV, was identified in Lymantria dispar M nuclear polyhedrosis virus (LdMNPV). Cotransfection of AcMNPV DNA and a plasmid carrying the LdMNPV gene into IPLB-Ld652Y cells results in AcMNPV replication. The gene maps between 43.3 and 43.8 map units on the 162-kbp genome of LdMNPV. It comprises a 218-codon open reading frame and encodes a polypeptide with a predicted molecular mass of 25.7 kDa. The predicted polypeptide is glutamic acid and valine rich and negatively charged, with a pI of 4.61. No protein sequence motifs were identified, and no matches with known nucleotide or peptide sequences were found in the AcMNPV genome or database searches that suggest how this gene might function. A recombinant AcMNPV bearing the LdMNPV gene overcomes a block in protein synthesis observed in AcMNPV-infected IPLB-Ld652Y cells. Using Southern blotting techniques, we were unable to identify a homolog in Orgyia pseudotsugata M nuclear polyhedrosis virus, a baculovirus that is routinely propagated in IPLB-Ld652Y cells. This suggests that the LdMNPV host range is unique among the baculoviruses studied to date. We named this gene hrf-1 (for host range factor 1).
Structural analysis of the two tandemly repeated acid phosphatase genes in yeast (1984)

We have sequenced the genetically linked genes for repressible (PHO5) and and constitutive (PHO3) acid phosphatase from S. cerevisiae. Both genes are located on a 3.91 Kb BamHI and HpaI fragment, in the order (5') PHO5, PHO3 (3'). The mRNA transcripts have been analysed by S1-nuclease mapping. They show heterogenous initiation sites. Each of the PHO5 and PHO3 genes codes for 467 amino acids as deduced from the DNA sequence. The coding regions of the two genes show homology both at the nucleotide (82%) and the amino acid (87%) level. In the coding sequences, long stretches of homologous regions are flanked by small non-homologous regions. The nucleotide homology (65%) extends to some length into the 5' and 3' non-coding flanking sequences. Further upstream sequences are unrelated. The comparison of the NH2-terminal amino acid sequence deduced from the nucleotide sequence, with that of purified repressible acid phosphatase revealed the presence of a putative signal peptide.
Switchgear and control handbook (1977)

Functions of industrial switchgear systems considerations for selecting swichgear and controls seismic and other environmentally catastrophic requirements and considerations motor types and characteristics control circuit devices metal-clad switchgear distribution panelboards and switchboards variable frequency solid state drivers controlling comutated motors small speciality motors, safety, maintenance.
Disease-Associated Chromatin Conformation and Therapeutic Implications In Leukemia (2013)

Disease- or treatment-associated chromatin conformation has yet to be illustrated. Here we first demonstrate that monocytic and erythroid leukemia cell lines have distinctly different chromatin conformation at the PU.1 locus: a looped, connected, RNA-polymerase-II-bound, active conformation in the former and a disconnected, inactive conformation in the latter. These conformations undergo opposite transformations, becoming more active in the erythroid leukemia line and less active in the monocytic leukemia line, in response to both DNA and histone hypomethylating drugs.To explore the underlying mechanisms we developed a novel method to analyze DNA modifications. We demonstrate that the erythroid leukemia line has a marked drug-responsive change in both hydroxymethyl-CpG and 5-meythyl-CpG at the promoter, whereas the monocytic leukemia line has a higher level bivalent histone/chromatin with co-localized H3K4me3 and H3K27me3 at the enhancer. Consequently, the erythroid leukemia line is more sensitive to DNA hypomethylation while the monocytic leukemia line is more sensitive to histone hypomethylation. Further studies on clinical leukemia samples confirm the findings, and demonstrate that the leukemic cells from the clinical samples have different chromatin conformations with much more bivalent chromatin and denser DNA/histone modifiers and are more sensitive to hypomethylating drugs, compared to normal controls. Different chromatin conformations dictate preferential drug responses and open new diagnostic and therapeutic avenues. Disclosures: No relevant conflicts of interest to declare.
An efficient pipelined dataflow processor architecture (2003)

It is demonstrated that the principles of pipelined instruction execution can be effectively applied in data-flow computers, yielding an architecture that avoids the main sources of pipeline gaps during program execution in many conventional designs. The processing element uses an architecture called argument-fetch data-flow architecture. It has two parts: a data-flow instruction scheduling unit (DISU) and a pipelined instruction processing unit (PIPU). The PIPU is an instruction processor that uses many conventional techniques to achieve fast pipelined operation. The DISU holds the data-flow signal graph of the collection of data-flow instructions allocated to the processing element and maintains a large pool of enabled instructions available for execution by the PIPU. The architecture provides a basis for achieving high performance for many scientific applications. The trial design and fabrication of an enable memory, a key component of the DISU, are reported.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
High-Performance Quantum Dot Lasers and Integrated Optoelectronics on Si (2009)

This paper provides a review of the recent developments of self-organized In(Ga)As/Ga(Al)As quantum dot lasers grown directly on Si, as well as their on-chip integration with Si waveguides and quantum-well electroabsorption modulators. A novel dislocation reduction technique, with the incorporation of self-organized In(Ga,Al)As quantum dots as highly effective three-dimensional dislocation filters, has been developed to overcome issues associated with the material incompatibility between III-V materials and Si. With the use of this technique, quantum dot lasers grown directly on Si exhibit relatively low threshold current ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">J</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> =900 A/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ) and very high temperature stability ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> =278 K). Integrated quantum dot lasers and quantum-well electroabsorption modulators on Si have been achieved, with a coupling coefficient of more than 20% and a modulation depth of ~100% at a reverse bias of 5 V. The monolithic integration of quantum dot lasers with both amorphous and crystalline Si waveguides, fabricated using plasma-enhanced chemical-vapor deposition and membrane transfer, respectively, has also been demonstrated.
Using the new UK-WHO growth charts (2010)

The new UK growth charts for children aged 0-4 years (designed using data from the new WHO standards) describe the optimal pattern of growth for all children, rather than the prevailing pattern in the UK (as with previous charts) The new charts are suitable for all ethnic groups and set breast feeding as the norm UK children match the new charts well for length and height, but after age 6 months fewer children will be below the 2nd centile for weight or show weight faltering, and more will be above the 98th centile The new charts look different: they have a separate preterm section, no lines between 0 and 2 weeks, and the 50th percentile is no longer emphasised The charts give clear instructions on gestational correction, and there is a new chart for infants born before 32 weeks' gestation The instructions advise on when and how to measure and when a measurement or growth pattern is outside the normal range The charts include a "look-up" tool for determining the body mass index centile from height and weight centiles without calculation and aid for predicting adult height The charts and supporting educational materials can be downloaded from www.growthcharts.rcpch.ac.uk adopted the WHO standard as it establishes the breastfed child as the norm, is suitable for all ethnic groups, and defines optimal growth. 4 The new charts amalgamate WHO data from age 2 weeks, with recalculated British 1990 (UK90) birth data.These data were used in preference to those of the WHO standard as the WHO dataset has no preterm birth data and the WHO term birth weights were appreciably lower. 4
Viscoelastic melt behavior of poly(2,6-dimethyl-1,4-phenylene oxide), high-impact polystyrene, and a 35–65 blend (1979)

The viscoelastic melt behavior of poly(2,6-dimethyl-1,4-phenylene oxide) (PPO1 PPO is a registered trademark of the General Electric Company. resin), high-impact polystyrene (HIPS), and a 35–65 blend of these polymers has been characterized by measuring the steady shear viscosity and primary normal stress difference and the dynamic storage and loss moduli as functions of shear rate or frequency and temperature. Time–temperature superpositioning was used to generate master curves of each type of data for a reference temperature of 260°C. This procedure required five different empirical shift factors for each material. These shift factors show large differences between PPO resin and HIPS and exhibited large deviations from the WLF equation with universal constants. This result suggests that the temperature dependence of the relaxation processes in PPO resin is significantly different from the temperature dependence of HIPS relaxations. Flow activation energies computed from the viscosity data for PPO resin are much higher and more shear sensitive than those calculated for HIPS. The computed relaxation spectra clearly display the effect of long-time relaxation mechanisms associated with PPO molecules when compared to HIPS. The 35–65 blend exhibits general rheological compatibility with material parameters and responses intermediate between PPO resin and HIPS. This result is indicative of a high degree of segmental mixing for the two components in the blend.
Naphthalimides as Anticancer Agents: Synthesis and Biological Activity (2001)

Naphthalimides are a class of compounds with high antitumor activity upon a variety of murine and human tumor cells. These compounds bind to DNA by intercalation of the chromophore and two of them, mitonafide and amonafide, were used in clinical trials. The therapeutic properties of these lead drugs were improved by designing bisintercalating agents. One of these, elinafide, showed intense in vitro and in vivo activity and is currently being used in clinical trials against solid tumors. In this paper, the history of elinafide is described.
Metering low-quality steam-water flows (1977)

The simultaneous measurement of mass flow rate and quality of low-quality steam-water flows is of primary interest in evaluating and monitoring the flow from geothermal resources. The experience acquired at LLL in attempting to perform such measurements with a double flash (meter-valve-meter) arrangement using orifices and venturis is related. The mass flow correlations proposed in the literature are reviewed and a new correlation based on the energy equation is introduced. The data are presented and evaluated in light of these correlations. Directions for future research in this area are suggested.
<i>Helicobacter pylori</i> and gastric diseases (1998)

The isolation of Helicobacter pylori from clinical specimens by Marshall and Warren 15 years ago1 launched revolutions in gastroenterology and microbiology. 2 3 Like other revolutions in history, the original directions of the H pylori story have changed in response to conflicting ideologies, observation, and practices. Currently, enthusiasts, drug companies, and the lay press are putting pressure on physicians to eliminate H pylori from all patients, symptomatic or not, in whom it is detected. There is little evidence that this is appropriate, and management will continue to change as new knowledge emerges and socioeconomic environments change in ways that are relevant to H pylori and clinical medicine. This article looks at past and current trends to anticipate the future of these common bacteria and the disorders associated with them.

H pylori is one of a large family of related bacteria that are well adapted to persist in the stomachs of vertebrates for the life span of their hosts. It is likely that H pylori has colonised our stomachs since well before we became humans.4 Studies of primates and human populations in developing countries suggest that, until the last century, nearly all humans carried H pylori or closely related bacteria in their stomachs. H pylori can thus be regarded as indigenous or “normal” flora, which most humans acquire within the first few years of childhood and then carry for life.

With socioeconomic development, fewer children are acquiring H pylori .5 This is a worldwide phenomenon that seems to have preceded the introduction of antibiotics, although it may have been accelerated by their widespread use. The reasons for the decline in the prevalence of H pylori colonisation are unknown. Improved nutrition and clean water have been proposed. An alternative hypothesis is that most transmission is from child to child …