gebhart/patrepeval huggingface dataset:
Rhodium complexes of the water-soluble phosphine Ph2PCH2CH2NMe3+. Their complexes with hydride, olefin, and carbon monoxide ligands. Their use as olefin hydrogenation and hydroformylation catalysts in aqueous solution and in aqueous/organic solvent two-phase systems, and adsorbed on a cation-exchange resin (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRhodium complexes of the water-soluble phosphine Ph2PCH2CH2NMe3+. Their complexes with hydride, olefin, and carbon monoxide ligands. Their use as olefin hydrogenation and hydroformylation catalysts in aqueous solution and in aqueous/organic solvent two-phase systems, and adsorbed on a cation-exchange resinRichard T. Smith, R. Kurt Ungar, Laura J. Sanderson, and Michael C. BairdCite this: Organometallics 1983, 2, 9, 1138–1144Publication Date (Print):September 1, 1983Publication History Published online1 May 2002Published inissue 1 September 1983https://pubs.acs.org/doi/10.1021/om50003a012https://doi.org/10.1021/om50003a012research-articleACS PublicationsRequest reuse permissionsArticle Views559Altmetric-Citations101LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cloning of nascent monkey DNA synthesized early in the cell cycle. (1985)

To study the structure and complexity of animal cell replication origins, we have isolated and cloned nascent DNA from the onset of S phase as follows: African green monkey kidney cells arrested in G1 phase were serum stimulated in the presence of the DNA replication inhibitor aphidicolin. After 18 h, the drug was removed, and DNA synthesis was allowed to proceed in vivo for 1 min. Nuclei were then prepared, and DNA synthesis was briefly continued in the presence of Hg-dCTP. The mercury-labeled nascent DNA was purified in double-stranded form by extrusion (M. Zannis-Hadjopoulos, M. Perisco, and R. G. Martin, Cell 27:155-163, 1981) followed by sulfhydryl-agarose affinity chromatography. Purified nascent DNA (ca. 500 to 2,000 base pairs) was treated with mung bean nuclease to remove single-stranded ends and inserted into the NruI site of plasmid pBR322. The cloned fragments were examined for their time of replication by hybridization to cellular DNA fractions synthesized at various intervals of the S phase. Among five clones examined, four hybridized preferentially with early replicating fractions.
Localization of the 12.6-kDa FK506-binding Protein (FKBP12.6) Binding Site to the NH2-terminal Domain of the Cardiac Ca2+ Release Channel (Ryanodine Receptor) (2003)

The 12.6-kDa FK506-binding protein (FKBP12.6) interacts with the cardiac ryanodine receptor (RyR2) and modulates its channel function. However, the molecular basis of FKBP12.6-RyR2 interaction is poorly understood. To investigate the significance of the isoleucine-proline (residues 2427-2428) dipeptide epitope, which is thought to form an essential part of the FKBP12.6 binding site in RyR2, we generated single and double mutants, P2428Q, I2427E/P2428A, and P2428A/L2429E, expressed them in HEK293 cells, and assessed their ability to bind GST-FKBP12.6. None of these mutations abolished GST-FKBP12.6 binding, indicating that this isoleucine-proline motif is unlikely to form the core of the FKBP12.6 binding site in RyR2. To systematically define the molecular determinants of FKBP12.6 binding, we constructed a series of internal and NH(2)- and COOH-terminal deletion mutants of RyR2 and examined the effect of these deletions on GST-FKBP12.6 binding. These deletion analyses revealed that the first 305 NH(2)-terminal residues and COOH-terminal residues 1937-4967 are not essential for GST-FKBP12.6 binding, whereas multiple sequences within a large region between residues 305 and 1937 are required for GST-FKBP12.6 interaction. Furthermore, an NH(2)-terminal fragment containing the first 1937 residues is sufficient for GST-FKBP12.6 binding. Co-expression of overlapping NH(2) and COOH-terminal fragments covering the entire sequence of RyR2 produced functional channels but did not restore GST-FKBP12.6 binding. These data suggest that FKBP12.6 binding is likely to be conformationdependent. Binding of FKBP12.6 to the NH(2)-terminal domain may play a role in stabilizing the conformation of this region.
Permanent magnet bearings and couplings (1981)

The coupling energy between elementary dipoles enables the calculation of forces and stiffnesses between small permanent magnets. The results are used to synthesize all the different basic configurations of magnetic bearings and magnetic couplings. This method enables us to predict some of their specific properties and the approximate calculation of their characteristics. It can be extended to all devices where forces are created between permanent magnets.
In vivo EPR spectroscopy of free radicals in the heart. (1994)

Electron paramagnetic resonance (EPR) spectroscopy can be applied to directly measure free radicals; however, it has not been possible to measure important biologic radicals in situ because conventional spectrometer designs are not suitable for the performance of measurements on large aqueous structures such as whole organs or tissues. We describe the design, construction, and application of instrumentation developed in an effort to obtain optimum performance in measuring free radicals in intact biologic organs or tissues. This spectrometer consists of a 1- to 2-GHz microwave bridge with the source locked to the resonant frequency of a specially designed recessed gap, loop-gap resonator. The principles of resonator design and construction are analyzed and described. Using this spectrometer radical concentrations as low as 0.4 microM in aqueous solutions could be measured. Studies of isolated beating hearts involving simultaneous real time measurements of free radicals and cardiac contractile function are performed. This in vivo EPR technique is applied to study the kinetics of free radical uptake and metabolism in normally perfused and globally ischemic hearts. In addition, it is demonstrated that this technique can be used to noninvasively measure tissue oxygen consumption. Thus, low frequency EPR spectroscopy offers great promise in the study of in vivo free radical generation and the effects of this radical generation on whole biologic tissues.
Optimization of the digital Silicon Photomultiplier for Cherenkov light detection (2012)

The Silicon Photomultiplier is a promising alternative to fast vacuum photodetectors. We developed a fully digital implementation of the Silicon Photomultiplier. The sensor is based on a single photon avalanche photodiode (SPAD) integrated in a standard CMOS process. Photons are detected directly by sensing the voltage at the SPAD anode using a dedicated cell electronics block next to each diode. This block also contains active quenching and recharge circuits as well as a one bit memory for the selective inhibit of detector cells. A balanced trigger network is used to propagate the trigger signal from all cells to the integrated time-to-digital converter. Photons are detected and counted as digital signals, thus making the sensor less susceptible to temperature variations and electronic noise. The integration with CMOS logic has the added benefit of low power consumption and possible integration of data post-processing in the sensor. In this paper, we discuss the sensor architecture together with its characteristics, and its possible optimizations for applications requiring the detection of Cherenkov light.
Generation of a permanent cell line that supports efficient growth of Marek′s disease virus (MDV) by constitutive expression of MDV glycoprotein E (2002)

A recombinant cell line (SOgE) was established, which was derived from the permanent quail muscle cell line QM7 and constitutively expressed the glycoprotein E (gE) gene of Marek's disease virus serotype 1 (MDV-1). The SOgE cell line supported growth of virulent (RB-1B) and vaccine (CVI988, 584Ap80C) MDV-1 strains at a level comparable with that of primary chicken embryo cells (CEC). The SOgE cell line was used to produce a vaccine against Marek's disease. Chickens were immunized at 1 day old with 10(3) p.f.u. CVI988 produced on either CEC or SOgE cells. Challenge infection was performed at day 12 with hypervirulent Italian MDV-1 strain EU1. Whereas 7/7 or 6/6 animals, respectively, immunized with SOgE or QM7 cells alone developed Marek's disease, only 1/8 animals from both CVI988-immunized groups exhibited signs of disease, suggesting that SOgE cells are a valuable permanent cell culture system for MDV-1 vaccine production.
Evolution of epitaxial structure and morphology : symposium held November 27-December 1, 1995, Boston, Massachusetts, U.S.A. (1996)

The evolution of epitaxial structure and morphology has assumed enormous scientific and technological importance in many areas of materials science. From the growth of magnetic multilayers to the fabrication of semiconductor devices, it is generally recognized that an understanding of microstructural development is fundamental to the control of the electronic, magnetic and mechanical properties of thin films. This book from MRS focuses on the structure and morphology of epitaxial systems with a particular emphasis on the time evolution of these properties as growth proceeds. It brings together advances to assess the relative roles of wetting and cohesion, reconstruction, surface and interfacial energy, misfit stress, and defect generation and propagation. It covers a broad mix of work, from basic studies of epitaxial metals and semiconductors to their application in thin-film electronic materials technology. Topics include: growth monitoring and characterization; island-size distributions and kinetic roughening; surfactants, intermixing and alloying; evolution of large-scale structures; self-organized epitaxial structures; strain relaxation; strain relaxation; steps, adatoms and islands and interface roughness and interdiffusion.
Automatic myocardial segmentation by using a deep learning network in cardiac MRI (2017)

Cardiac function is of paramount importance for both prognosis and treatment of different pathologies such as mitral regurgitation, ischemia, dyssynchrony and myocarditis. Cardiac behavior is determined by structural and functional features. In both cases, the analysis of medical imaging studies requires to detect and segment the myocardium. Nowadays, magnetic resonance imaging (MRI) is one of the most relevant and accurate non-invasive diagnostic tools for cardiac structure and function. In this work we propose to use a deep learning technique to assist the automatization of myocardial segmentation in cardiac MRI. We present several improvements to previous works in this paper: we propose to use the Jaccard distance as optimization objective function, we integrate a residual learning strategy into the code, and we introduce a batch normalization layer to train the fully convolutional neural network. Our results demonstrate that this architecture outperforms previous approaches based on a similar network architecture, and that provides a suitable approach for myocardial segmentation. Our benchmark shows that the automatic myocardial segmentation takes less than 22 seg. for a volume of 128 × 128 × 13 pixels in a 3.1 GHz intel core i7.
Ruthenium-catalyzed dealkenative N-silylation of amines by substituted vinylsilanes (2014)

The ruthenium hydride complex-catalyzed N-silylation of primary and secondary amines with substituted vinylsilanes, with the general formula R(1)CH=CHSiR (where R(1) = H, Ph, n-Bu, Si(OEt)3), leading to the formation of a Si-N bond with the evolution of olefin is described. Vinylsilane acts as a silylative reagent and hydrogen acceptor. Under optimum conditions, the reaction offers an attractive route for the synthesis of silylamines. The preliminary mechanistic view of this novel general silylation reaction based on catalytic and deuterium labeling experiments, using NMR and GC-MS methods, confirm the synthetic observations.
Simulation-based optimization for material dispatching in a retailer network (2004)

This paper presents preliminary work done on simulation-based optimization of a stochastic material-dispatching system in a retailer network. The problem we consider is one of determining the optimal number of trucks and quantities to be dispatched in such a system. Theoretical solution models for versions of this problem can be found in the literature. Unlike most theoretical models, we can accommodate many real-life considerations, such as arbitrary distributions of the governing random variables, and all important cost elements, such as inventory-holding costs, stock-out costs, and transportation costs. We have used two techniques, namely, neuro-response surfaces and simulated annealing, for optimizing our system. We have also used a problem-specific heuristic, known as the mean demand heuristic, to provide us with a good starting point for simulated annealing and a benchmark for our other methods. Some computational results are also provided.
Metal diffused stripe waveguides: approximate closed form solution for lower order modes (1976)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. M. Hammer, "Metal diffused stripe waveguides: approximate closed form solution for lower order modes," Appl. Opt. 15, 319-320 (1976) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Nano-Magnetic Immunosensor Based on Staphylococcus Protein A and the Amplification Effect of HRP-Conjugated Phage Antibody (2015)

In this research, super-paramagnetic Fe3O4 nanoparticles (magnetic particles) were coated with Staphylococcus protein A (SPA) and coupled with polyclonal antibody (pcAb) to construct magnetic capturing probes, and HRP-conjugated phage antibody was then used as specific detecting probe to design a labeled immunosensor for trace detection of Staphylococcus aureus enterotoxin B (SEB). The linear detection range of the sensor was 0.008~125 µg/L, the regression equation was Y = 0.487X + 1.2 (R = 0.996, N = 15, p < 0.0001), the limit of detection (LOD) was 0.008 µg/L, and the limit of quantification (LOQ) was 0.008 µg/L. HRP-conjugated phage antibody, SPA and magnetic particles can enhance the sensitivity 4-fold, 3-fold and 2.6-fold higher, respectively. Compared with conventional double-antibody sandwich ELISA, the detection sensitivity of the sensor was 31-fold higher resulting from the integrated amplifying effect. The immunosensor integrates the unique advantages of SPA-oriented antibody as magnetic capturing probe, HRP-conjugated phage antibody as detecting probe, magnetic separation immunoassay technique, and several other advanced techniques, so it achieves high sensitivity, specificity and interference-resistance. It is proven to be well suited for analysis of trace SEB in various environmental samples with high recovery rate and reproducibility.
On-line extraction of modal characteristics from power system measurements based on Hilbert-Huang analysis (2009)

Hilbert-Huang has been used as a systematic approach to analyze and characterize the temporal evolution of nonlinear, time varying process in power systems. In this paper an efficient method for analyzing the local dynamics of transient oscillations using a local empirical mode decomposition (EMD) and the Hilbert transform is presented. Two novel approaches are investigated to characterize non-stationary issues. The first technique is a local implementation of the EMD technique, through a combination of a sliding window of finite length with the sifting process by blocks. The second method is an algorithm to compute the Hilbert transform using variable window filters. Approaches to extending Hilbert-Huang analysis to analyze the local properties of non-stationary signals are explored based on finite-impulse-response (FIR) designed using Kaiser window. Through this proposed methodology is possible to make an online analysis technique for measured data using the Hilbert-Huang method. These techniques are tested on time-synchronized phasor measurements collected by PMUs. Offline technique is used in the analysis of transient phenomena emerged in power systems to compare results.
Configurable High Side Power Switch in Smart Power Technology (2007)

This paper presents a design approach based on the splitting of the power transistor for smart power applications. The design approach is applied to realize a high side power switch with a configurable output in smart power technology. Experimental results are also presented and discussed.
Use of a Ceramic Membrane Reactor for the Oxidative Dehydrogenation of Ethane to Ethylene and Higher Hydrocarbons (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUse of a Ceramic Membrane Reactor for the Oxidative Dehydrogenation of Ethane to Ethylene and Higher HydrocarbonsJoaquin Coronas, Miguel Menendez, and Jesus SantamariaCite this: Ind. Eng. Chem. Res. 1995, 34, 12, 4229–4234Publication Date (Print):December 1, 1995Publication History Published online1 May 2002Published inissue 1 December 1995https://pubs.acs.org/doi/10.1021/ie00039a011https://doi.org/10.1021/ie00039a011research-articleACS PublicationsRequest reuse permissionsArticle Views474Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Interference characteristics in inter-vehicle communication from oncoming vehicles (1999)

The use of inter-vehicle communication (IVC) is considered an integral part of future intelligent transportation systems. Although several communication protocols have been proposed, the problems of interference have largely been ignored. In particular, the problem of interference from vehicles in oncoming lanes has not been investigated before. We examine the problem of interference from vehicles in oncoming lanes and show that the worst case presents a level of interference which must be avoided. The results in this paper are confirmed by both theoretic modeling and computer simulation using a Rician fading model in the millimeter wave band. The use of directional or beam antennas, coupled with separating the frequency band into forward transmit/reverse receive, and reverse transmit/forward receive is suggested as the solution to the problems of interference from oncoming vehicles.
Neovascularization in human coronary atherosclerotic lesions (1996)

Neovessels within human coronary atherosclerotic lesions are frequently observed, but their pathophysiological significance is still subject to debate. Also, the origin of these vessels and their pathways in the arterial wall are not well-known. In this study, we describe the transmural pathway and the frequency of neovessels both in vivo and in autopsy cases. Atherosclerotic coronary arteries were obtained during autopsy in 10 subjects without previous cardiovascular symptoms. In 25 patients undergoing percutaneous intervention for either stable or unstable angina, plaque fragments were retrieved by directional coronary atherectomy. In the autopsy study, at least one coronary artery in each case showed some degree of neointimal proliferation, characterized by smooth muscle cells in a dense extracellular matrix. A neovascularization process was seen in 17.5% of the 40 samples analyzed. In 2 cases, the transmural pathway of the neovessels could be tracked: serial sections revealed the emergence of an arteriole from the adventitia of the coronary artery, its transmedial course as a capillary, and its opening into the coronary arterial lumen. In symptomatic patients who underwent atherectomy, neovessels were found in 1 of 9 patients with stable angina (11%) and in 8 of 16 patients with unstable angina (50%, P < 0.05). Mostly, the neovessels appeared as capillaries cut in their short axis. In 2 cases, however, the capillary was seen in its longitudinal axis, and its pathway could be traced through the atherosclerotic lesion to its opening in the coronary lumen, as in the autopsy study. Therefore, neovessels frequently develop in the atherothrombotic plaque, both in asymptomatic and anginal patients. In the latter group, the proliferation of neovessels is more frequent in acute coronary syndromes. These findings have several implications, in particular for percutaneous coronary angioplasty and related procedures, such as local drug delivery.
Extremely Efficient and Recyclable Absorbents for Oily Pollutants Enabled by Ultrathin-Layered Functionalization (2014)

Oils and organic solvents that leak into water bodies must be promptly removed to avoid ecological disasters, for example, by selective absorption using oleophilic absorbents. However, it remains a challenge for the low-cost synthesis of efficient and recyclable absorbents for oily pollutants. By surface functionalization to inexpensive polyurethane (PU) foams, we synthesize oil absorbents exhibiting the highest absorption capacity and the best recyclability among all polymeric absorbents. The synthesis is enabled by atomic layer deposition of ∼5 nm-thick Al2O3 transition layer onto the skeleton surface of PU foams, followed by coupling a single-molecule layer of silanes to the Al2O3 layer. The sub-10 nm functionalization layer provides the PU foam an outstanding water-repelling and oil-absorbing functionality without compromising its high porosity and elasticity. The functionalized foam is able to quickly absorb oily pollutants spread on water surfaces or precipitated in water with a capacity more than 100 times its own weight. This ultrathin-layer-functionalization method is also applicable to renewable porous biomaterials, providing a sustainable solution for oil spills. Moreover, we propose devices than can continuously operate to efficiently collect oil spills from water surfaces based on the functionalized PU foam developed in this work.