gebhart/patrepeval huggingface dataset:
Non-fouling microfluidic chip produced by radio frequency tetraglyme plasma deposition (2007)

This Technical Note presents the direct surface modification of a glass/PTFE hybrid microfluidic chip, via radio frequency glow discharge plasma polymerisation of tetraethlylene glycol dimethylether (tetraglyme), to produce hydrophilic, non-fouling, PEO-like surfaces. We use several techniques including X-ray photoelectron spectroscopy (XPS), direct enzyme-linked immunosorbent assays (ELISA) and immunofluorescent imaging to investigate the channel coatings. Our results indicate the successful deposition of a PEO-like coating onto microchannel surfaces that has both solution and shelf stability (>3 months) and is capable of preventing fibrinogen adsorption to the microchannel surfaces.
Conformational change of mastoparan from wasp venom on binding with phospholipid membrane (1983)

The conformational change upon binding with phospholipid membrane has been studied of mastoparan from wasp venom, a tetradecapeptide causing the degranulation of mast cells. The 270-MHz 1H-NMR spectra and CD spectra indicate that the mastoparan molecule takes the alpha-helical conformation in methanol solution, but a much less ordered form in aqueous solution. On binding with phospholipid membrane, the alpha-helical conformation is formed even in aqueous medium. Such a conformational change is primarily due to the interaction between the aliphatic side chains of mastoparan and the hydrophobic interior of phospholipid membrane, in contrast to the case of melittin from bee venom.
Membrane mass spectrometer inlet for quantitation of nitric oxide (1993)

Nitric oxide (NO) is an important physiological and biochemical messenger that may be involved in endogenous carcinogenesis and cell toxicity via formation of N-nitroso compounds or direct DNA damage by nitrosating agents arising from the reaction of NO with O2. To study the reaction of NO with O2 in model systems and the formation and disappearance of NO in more physiological systems such as cell cultures, we adapted and optimized a membrane mass spectrometer inlet specifically for such analyses. The inlet consisted of Silastic tubing inserted into a Swagelok 'tee', which was attached to the mass spectrometer via the tuning probe. Kinetics of NO disappearance can be followed under electron impact conditions until NO2 interferes via the formation of NO+ during fragmentation of NO2+. The aqueous NO concentration for minimum detection was determined to be 1.4 microM. The inlet response time to step changes in aqueous NO concentrations was 7.0 s, fast enough to permit real-time measurements of aqueous NO changes upon addition of O2. Finally, the depletion of aqueous NO was observed in the presence of O2. The relative steady state responses of inlets designed for gas or aqueous samples, and their relative response times, are explained by an analysis based on mass transfer theory.
Cardiac complications of protein-sparing modified fasting (1978)

Cardiovascular abnormalities developed in a patient during a proteinsparing modified fasting diet. Syncope was the complaint at the time of examination. Hypotension, persistent QT<i>c</i>interval prolongation, and a low QRS voltage were observed before the development of refractory ventricular tachycardia. At autopsy, antemortem thrombi were attached to the left ventricular endocardium and a fenestrated aortic valvule. Strick proteinsparing modified fasting is not without risk of sudden death even with close medical supervision. (<i>JAMA</i>240:120-122, 1978)
A Novel Layer Jamming Mechanism With Tunable Stiffness Capability for Minimally Invasive Surgery (2013)

This paper presents a novel “layer jamming” mechanism that can achieve variable stiffness. The layer jamming mechanism exploits the friction present between layers of thin material, which can be controlled by a confining pressure. Due to the mechanism's hollow geometry, compact size, and light weight, it is well suited for various minimally invasive surgery applications, where stiffness change is required. This paper describes the concept, the mathematical model, and a tubular snake-like manipulator prototype. Various characteristics of layer jamming, such as stiffness and yield strength, are studied both theoretically and experimentally.
Separation of cysteine proteinase inhibitors from psoriatic scale. (1983)

Inhibitors of cysteine proteinases from extracts of psoriatic scales and from scrapings of normal skin surface were separated by using immunochemical, electrophoretic and chromatographic methods. The total inhibitory capacity of cysteine proteinases measured as inhibition of papain, was higher in the extracts from psoriatic scales than from normal skin surface scrapings. In normal skin samples only one inhibitor, acidic inhibitor, was identified while altogether three separate inhibitors were revealed in psoriatic extracts: an acid inhibitor (ACPI) with pI at 4 . 7-5 . 5, molecular weight around 12,000, a near-neutral inhibitor (NCPI) with pI at 6 . 0-6 . 5, molecular weight around 12,000, and a slightly alkaline inhibitor with pI around 7 . 0-7 . 5 and molecular weight 37,000. Two to three isoelectric variants were found in all these inhibitors. Quantitatively, the acid inhibitor is the most abundant one. The low molecular weight inhibitors (ACPI and NCPI) were localized with PAP method in the upper spinous cell layers in formalin-fixed skin sections. The slightly alkaline inhibitor with mol.wt 37,000 reacted in immunodiffusion with a commercial rabbit polyvalent antiserum. The abundance of cysteine proteinase inhibitors in the psoriatic lesion is considered as a local effort to compensate for the high cysteine proteinase activity.
Estudio clínico-experimental de un fóbico: Estudios de psicología de Szondi (1960)

Continuamos nuestros estudios sobre las estructuras instintivas profundas, segun las doctrinas y metodos del Analisis del Destino, del eminente heredo-psiquiatra, psicoanalista y psicoterapeuta Dr. L. Szondi. El caso que hoy presentamos es una muestra de la combinacion efectiva entre los metodos clinicos, bioelectricos y psicologicos. Por el empleo sistematico de estos metodos conjugados en la comprension adecuada de los pacientes mentales, la clinica se coloca en mejores condiciones para un diagnostico exacto y para un mas eficaz tratamiento.
Rapp, Anders. Studies of the Postglacial Development of Mountain Slopes. These de Ph.D., Faculté des Sciences, Uppsala, mai 1961, 264 pages, ill. (1961)

Rapp, Anders. Studies of the Postglacial Development of Mountain Slopes. These de Ph.D., Faculté des Sciences, Uppsala, mai 1961, 264 pages, ill.. Un article de la revue Cahiers de géographie du Québec (Mélanges géographiques canadiens offerts à Raoul Blanchard) diffusée par la plateforme Érudit.
Carrier thermalization in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Cu</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>O: Phonon emission by excitons (1991)

We have observed the energy distribution of nonthermalized excitons in the semiconductor ${\mathrm{Cu}}_{2}$O on a time scale of 10 ps following resonant creation by a short (5-ps) laser pulse. We present a model for the change in the energy distribution of carriers as they cool to take on a Maxwell-Boltzmann distribution at the lattice temperature. Emission and absorption of acoustic phonons via the deformation-potential interaction and emission and absorption of nonpolar optical phonons are taken into account in an exact Boltzmann equation that is solved numerically. The model fits the observed distributions well, for a value of the deformation potential in agreement with hydrostatic-pressure and uniaxial-stress measurements. Single-optical-phonon emission is found to be rather slow, with a time scale of about 30 ps. We also present evidence for a fast two-optical-phonon emission process in ${\mathrm{Cu}}_{2}$O. Finally, we consider the effects of exciton-exciton interactions and obtain an upper bound on the range of exciton-exciton interactions from these experiments.
Statistical properties of elastograms (2002)

Accurate and precise displacement estimates are the key to obtaining high-quality elastograms. In elastographic imaging, echo-signals acquired before and after tissue compression are cross-correlated and the location of the cross-correlation maximum is used for determining the local tissue displacement and deformation. A stochastic strain model under static compression is discussed, and an inverse coordinate transformation relating the post-compression coordinate to the pre-compressed coordinate is introduced. Analytic formulas for the cross-correlation are provided and used to analyse stochastic strain-induced effects. Displacement causes decorrelation of the pre- and post-compression signals and consequently results in a nonstationary cross-correlation function. Adjusting experimental and signal processing variables, such as stretching the post-compression echo-signal and/or shaping the ultrasonic pulse are shown to significantly increase the accuracy of the displacement estimates.
Some new rearrangements in nitrogen heterocyclic chemistry. (1968)

The oxidation of 3-niono- and 3, 4-di-substituted 2-pyrazolin-5-ones was studied to determine whether the pyrazol-3-one intermediates generated would decompose with loss of nitrogen to give cyclopropenones. Cyclopropenones were not formed however; this parallels the behaviour of 3-indazolones which had been shown not to give benzocyclopropenone. 4, 5-Diphenylpyrazol-3-one lost nitrogen and carbon monoxide to give diphenylacetylene, and nitrogen to give 2, 3, 6, 7-tetraphenylpyrazolo-(l,2a)-pyrazol-l,5- dione. The unstable alpha-carbonyl-azo intermediates from 2-pyrazolin-5-ones were trapped with tetracyclone to give stable Diels Alder adducts in good yield. When heated these adducts partly undergo a retro-Diels Alder reaction and partly undergo a novel molecular rearrangement, paralleled in the mass spectrometer, to give carbon dioxide and 1, 7a-diazaindenes. (This is described in Section 1). Efforts towards the synthesis of 5, 6-diphenyl-l, 2, 3-triazin- 4-one are described since its 3-amino derivative should give diphenylcyclopropenone on oxidation. Amination of 3, 4-diphenyl-2-pyrazolin-5-one caused ring expansion to 5, 6-diphenyl-l, 2, 3, 4-tetrahydro-1, 2, 4-triazin-3-one, which on oxidation gave 5, 6-diphenyl-1, 2, 4-triazin-3-one. Amination of the latter caused ring contraction, however, to give 4, 5-diphenylimidazolin-2-one with hydroxylamine-0-sulphonic acid, and 4, 5-diphenyl-l, 2, 3-triazole with chloramine. (This is described in Section 2). l-Amino-3, 4, 5, 6-tetraphenyl-2-pyridone was prepared as a possible precursor to hexaphenyl-1, 7a-diazaindene (see above). When oxidised with lead tetra-acetate it underwent an unusual rearrangement to give 3, 4, 5, 6-tetraphenylpyridazine; evidence for a nitrene intermediate was provided by oxidation of the N-amino-pyridone in dimethyl sulphoxide when the nitrene was trapped as the sulphoximine. Pyrolysis of this gave the same products as the oxidation reaction. The nitrene formed by oxidation of the hydrazine, and by photolysis of the sulphoximine, was trapped with cyclohexene to give the same aziridine. By contrast, oxidation of N-aminophenanthridone gave 4, 5-benzocoumarin and l-amino-2, 3-diphenyl-4-quinolone gave a bis-quinolone. (This is described in Section 3). The preparation of 2, 3-bis-(m-methoxyphenyl)-cyclopropenone and the attempted oxidative coupling of this and the bis-phenol to give the phenanthracyclopropenone system are described in the Appendix. Mechanisms are proposed for all the new reactions described.
Near-Optimal Low Complexity MLSE Equalization (2008)

An iterative maximum likelihood sequence estimation (MLSE) equalizer (detector) with hard outputs, that has a computational complexity quadratic in the data block and the channel length, is proposed. Its performance is compared to the Viterbi MLSE algorithm that has a computational complexity that is linear in the block length and exponential in the channel memory length. It is shown via computer simulation that the proposed iterative MLSE detector is able to detect binary phase-shift keying (BPSK) signals in systems with significantly larger channel length than what is possible with the Viterbi algorithm, for frequency selective Rayleigh fading channels.
An ocean bottom, D component magnetometer (1967)

Abstract The distribution of electric conductivity in the crustal and upper mantle materials beneath the ocean may be estimated from measurements of the relationship between the magnetic fluctuations and the induced electric field at the ocean bottom. Techniques for the measurement of the electric field have been available for a few years. The horizontal magnetic fluctuations to the magnetic east, usually called D, can be recorded with a simple instrument placed on the sea floor at any depth. This instrument uses a magnet pair which orients itself among the main horizontal field H. The coupling of the magnets to the mirror of a sensitive optical lever is delayed until the instrument has reached the bottom. There is no need to perform any orientation in situ.The instrument resolves 1 gamma or less and has a dynamic range of at least 2500 gamma . It is capable of recording for approximately 40 days at the rate of 30 readings per hour on self-contained dry cells. It is lowered to the sea floor and recovered by means of a mooring line connected to a surface float. The low-profile supporting tripod is effectively decoupled from the mooring tackle as evidenced by the lack of motion of the magnetometer during 26 days of recording.A sample of the observed fluctuations on the floor of the North Pacific Ocean, 600 km offshore, is given.
Antiallergic Effects of Lactobacillus pentosus Strain S-PT84 Mediated by Modulation of Th1/Th2 Immunobalance and Induction of IL-10 Production (2007)

Despite heat-killing, S-PT84 exhibited antiallergic effects by modulating the Th1/Th2 balance and inducing regulatory T cells. The L. pentosus strain S-PT84, which is of plant origin and isolated from a traditional Japanese food, is expected to be useful for treatment of many immune diseases including allergies, tumors, infectious diseases and auto-immune diseases.
High Availability of Clouds: Failover Strategies for Cloud Computing Using Integrated Checkpointing Algorithms (2012)

This paper presents an approach for providing high availability to the requests of cloud's clients. To achieve this objective, fail over strategies for cloud computing using integrated check pointing algorithms are purposed in this paper. Purposed strategy integrate check pointing feature with load balancing algorithms and also make multilevel checkpoint to decrease check pointing overheads. For implementation of purposed fail over strategies, a cloud simulation environment is developed, which has the ability to provide high availability to clients in case of failure/recovery of service nodes. Also in this paper comparison of developed simulator is made with existing methods. The purposed fail over strategy will work on application layer and provide highly availability for Platform as a Service (PaaS) feature of cloud computing.
Friendly NGO Delegation from Neighboring Countries Visiting China (2012)

At the invitation of the Chinese Association for International Understanding (CAFIU), a 17 - member delegation consisted of friendly NGO personnel from Bangladesh, Nepal, Sri Lanka and Indonesia visited China from October 22 to November 2. During their stay in Beijing, CAFIU Secretary-General Ni Jian, head of a department of Ministry of Agriculture and a scholar from Tsinghua University gave briefings on China’s basic national conditions, China’s
O ANTIGO E O MODERNO NO IMAGINÁRIO (2007)

Americanae nace como un proyecto conjunto que surge dentro de la Red Europea de Información y Documentación sobre América Latina (REDIAL), y que ha afrontado la Biblioteca de la Agencia Española de Cooperación Internacional para el Desarrollo (AECID). Esta nueva biblioteca virtual hace más accesibles los libros digitales de tema americanista a los investigadores y usuarios interesados de cualquier parte del mundo.
Time Frequency and Wavelets in Biomedical Signal Processing (1997)

Brimming with top articles from experts in signal processing and biomedical engineering, Time Frequency and Wavelets in Biomedical Signal Processing introduces time-frequency, time-scale, wavelet transform methods, and their applications in biomedical signal processing. This edited volume incorporates the most recent developments in the field to illustrate thoroughly how the use of these time-frequency methods is currently improving the quality of medical diagnosis, including technologies for assessing pulmonary and respiratory conditions, EEGs, hearing aids, MRIs, mammograms, X rays, evoked potential signals analysis, neural networks applications, among other topics. Time Frequency and Wavelets in Biomedical Signal Processing will be of particular interest to signal processing engineers, biomedical engineers, and medical researchers. Topics covered include: . Time-frequency analysis methods and biomedical applications. Wavelets, wavelet packets, and matching pursuits and biomedical applications. Wavelets and medical imaging. Wavelets, neural networks, and fractals
Apparatus for neutron diffraction at high pressure (1974)

Powder neutron diffraction data have been obtained on cesium metal above the two transitions at 42.5 and 43 kilobar using a piston cylinder apparatus. A Lucalox cylinder (high density Al2O3) (35.4 mm o.d., 6.35 mm i.d.) is radially supported by compressing two steel plates with a hydraulic ram leaving a neutron window between the plates ∼6 mm high. A 17° included angle was used between the cylinder and support plates. A tungsten carbide piston, driven by a second hydraulic ram, raised the pressure on the sample at three times the rate of increase of the support pressure.
ConDroid: Targeted Dynamic Analysis of Android Applications (2015)

Recent years have seen the development of a multitude of tools for the security analysis of Android applications. A major deficit of current fully automated security analyses, however, is their inability to drive execution to interesting parts, such as where code is dynamically loaded or certain data is decrypted. In fact, security-critical or downright offensive code may not be reached at all by such analyses when dynamically checked conditions are not met by the analysis environment. To tackle this unsolved problem, we propose a tool combining static call path analysis with byte code instrumentation and a heuristic partial symbolic execution, which aims at executing interesting calls paths. It can systematically locate potentially security-critical code sections and instrument applications such that execution of these sections can be observed in a dynamic analysis. Among other use cases, this can be leveraged to force applications into revealing dynamically loaded code, a simple yet effective way to circumvent detection by security analysis software such as the Google Play Store's Bouncer. We illustrate the functionality of our tool by means of a simple logic bomb example and a real-life security vulnerability which is present in hunderd of apps and can still be actively exploited at this time.
Functional Domains of α-Catenin Required for the Strong State of Cadherin-based Cell Adhesion (1999)

The interaction of cadherin-catenin complex with the actin-based cytoskeleton through alpha-catenin is indispensable for cadherin-based cell adhesion activity. We reported previously that E-cadherin-alpha-catenin fusion molecules showed cell adhesion and cytoskeleton binding activities when expressed in nonepithelial L cells. Here, we constructed deletion mutants of E-cadherin-alpha-catenin fusion molecules lacking various domains of alpha-catenin and introduced them into L cells. Detailed analysis identified three distinct functional domains of alpha-catenin: a vinculin/alpha-actinin-binding domain, a ZO-1-binding domain, and an adhesion-modulation domain. Furthermore, cell dissociation assay revealed that the fusion molecules containing the ZO-1-binding domain in addition to the adhesion-modulation domain conferred the strong state of cell adhesion activity on transfectants, although those lacking the ZO-1-binding domain conferred only the weak state. The disorganization of actin-based cytoskeleton by cytochalasin D treatment shifted the cadherin-based cell adhesion from the strong to the weak state. In the epithelial cells, where alpha-catenin was not precisely colocalized with ZO-1, the ZO-1-binding domain did not completely support the strong state of cell adhesion activity. Our studies showed that the interaction of alpha-catenin with the actin-based cytoskeleton through the ZO-1-binding domain is required for the strong state of E-cadherin-based cell adhesion activity.
Variations in circadian heart rate in psychiatric disorders: theoretical and practical implications (2013)

Background: Data are presented to demonstrate dimensions of variation in circadian heart rate in patients under treatment for a psychiatric disorder and to comment on their clinical relevance. Method: Serial recordings of 24-hour heart rates were obtained from individuals under treatment for a psychiatric disorder and from healthy volunteers. Results: The mean 24-hour heart rate can vary independently of the circadian rate pattern or “rate architecture.” Sleep and waking heart rate can vary independently. Variations in circadian heart rate are state-dependent: broadly different clinical states are associated with distinctly different patterns of circadian heart rate, particularly during sleep. Conclusion: Different regulatory mechanisms or pathways are involved in mediating different aspects of circadian heart rate. An analysis of circadian heart rate can contribute useful physiological adjunct information to psychiatric assessment and the monitoring of patient response to treatment. Keywords: anxiety, depression, neuroendocrine regulation
Improving content visibility for high‐ambient‐illumination viewable display and energy‐saving display (2011)

Abstract— Nowadays, low‐contrast viewing of LC displays (LCDs) occurs very often, which includes the viewing of mobile LCDs at high ambient illumination and the viewing of LCDs at low‐power mode. These cases result in low‐content visibility and low contrast, leading to an unpleasant viewing experience. In this paper, a technique to improve the perceived contrast and visibility of images at low‐contrast viewing conditions is proposed. The proposed approach enhances image brightness with content and ambient adaptive image brightening and highlights visual parts and boundaries with non‐photorealistic rendering. The proposed technique enables longer battery life for mobile LC devices and makes mobile LC devices viewable at high ambient illumination. It also enables TVs with extreme low‐power consumption and smart‐grid responsive TVs.
Inactivation of fecal bacteria in drinking water by solar heating (1996)

We report simulations of the thermal effect of strong equatorial sunshine on water samples contaminated with high populations of fecal coliforms. Water samples, heavily contaminated with a wild-type strain of Escherichia coli (starting population = 20 x 10(5) CFU/ml), are heated to those temperatures recorded for 2-liter samples stored in transparent plastic bottles and exposed to full Kenyan sunshine (maximum water temperature, 55 degrees C). The samples are completely disinfected within 7 h, and no viable E. coli organisms are detected at either the end of the experiment or a further 12 h later, showing that no bacterial recovery has occurred. The feasibility of employing solar disinfection for highly turbid, fecally contaminated water is discussed.