gebhart/patrepeval huggingface dataset:
User, metric, and computational evaluation of foveated rendering methods (2016)

Perceptually lossless foveated rendering methods exploit human perception by selectively rendering at different quality levels based on eye gaze (at a lower computational cost) while still maintaining the user's perception of a full quality render. We consider three foveated rendering methods and propose practical rules of thumb for each method to achieve significant performance gains in real-time rendering frameworks. Additionally, we contribute a new metric for perceptual foveated rendering quality building on HDR-VDP2 that, unlike traditional metrics, considers the loss of fidelity in peripheral vision by lowering the contrast sensitivity of the model with visual eccentricity based on the Cortical Magnification Factor (CMF). The new metric is parameterized on user-test data generated in this study. Finally, we run our metric on a novel foveated rendering method for real-time immersive 360° content with motion parallax.
4-Aminoquinolines Active against Chloroquine-Resistant Plasmodium falciparum: Basis of Antiparasite Activity and Quantitative Structure-Activity Relationship Analyses (2011)

Chloroquine (CQ) is a safe and economical 4-aminoquinoline (AQ) antimalarial. However, its value has been severely compromised by the increasing prevalence of CQ resistance. This study examined 108 AQs, including 68 newly synthesized compounds. Of these 108 AQs, 32 (30%) were active only against CQ-susceptible Plasmodium falciparum strains and 59 (55%) were active against both CQ-susceptible and CQ-resistant P. falciparum strains (50% inhibitory concentrations [IC50s], ≤25 nM). All AQs active against both CQ-susceptible and CQ-resistant P. falciparum strains shared four structural features: (i) an AQ ring without alkyl substitution, (ii) a halogen at position 7 (Cl, Br, or I but not F), (iii) a protonatable nitrogen at position 1, and (iv) a second protonatable nitrogen at the end of the side chain distal from the point of attachment to the AQ ring via the nitrogen at position 4. For activity against CQ-resistant parasites, side chain lengths of ≤3 or ≥10 carbons were necessary but not sufficient; they were identified as essential factors by visual comparison of 2-dimensional (2-D) structures in relation to the antiparasite activities of the AQs and were confirmed by computer-based 3-D comparisons and differential contour plots of activity against P. falciparum. The advantage of the method reported here (refinement of quantitative structure-activity relationship [QSAR] descriptors by random assignment of compounds to multiple training and test sets) is that it retains QSAR descriptors according to their abilities to predict the activities of unknown test compounds rather than according to how well they fit the activities of the compounds in the training sets.
Epidemiology of health and safety risks in agriculture and related industries. Practical applications for rural physicians. (1993)

Epidemiologic studies document that work in the agricultural sector is associated with many occupational health hazards. Exposure to organic dusts and airborne microorganisms and their toxins may lead to respiratory disorders. The burden of exposure-related chronic bronchitis, asthma, hypersensitivity pneumonitis, organic-dust toxic syndrome, and chronic airflow limitation can be diminished by appropriate preventive measures. The contribution of exposures to agricultural chemicals to cancers and neurodegenerative disorders is being investigated. Some studies document that farmers and those in related industries are at higher risk for the development of cancer of the stomach, soft tissue sarcoma, non-Hodgkin's lymphoma, and multiple myeloma. Chronic encephalopathy and Parkinson's and Alzheimer's diseases are being studied in relation to agricultural chemicals. The possible carcinogenicity and neurotoxicity of pesticides emphasize the need to promote the safe use of chemicals. Another area for health promotion programs is disabling injuries and traumatic deaths. Farm accidents are important because of their frequent occurrence among young people and disturbing fatality rates. Other health issues of concern in these industries include skin diseases, hearing loss, and stress.
An Integrated Chemical Reactor-heat Exchanger based on Ammonium Carbamate (2012)

<div class="section abstract"><div class="htmlview paragraph">In this work we present our recent effort in developing a novel heat exchanger based on endothermic chemical reaction (HEX reactor). The proposed HEX reactor is designed to provide additional heat sink capability for aircraft thermal management systems. Ammonium carbamate (AC) which has a decomposition enthalpy of 1.8 MJ/kg is suspended in propylene glycol and used as the heat exchanger working fluid. The decomposition temperature of AC is pressure dependent (60°C at 1 atmosphere; lower temperatures at lower pressures) and as the heat load on the HEX increases and the glycol temperature reaches AC decomposition temperature, AC decomposes and isothermally absorbs energy from the glycol. The reaction, and therefore the heat transfer rate, is controlled by regulating the pressure within the reactor side of the heat exchanger. The experiment is designed to demonstrate continuous replenishment of AC. This requires recovering the depleted glycol while expelling waste gases, dispersing and suspending fresh AC, and injecting the mixture into the heat exchanger. A gasketed plate heat exchanger is used as the reactor for this experiment, and heated water is used to provide the thermal load. The performance of the HEX reactor is characterized as a function of water flow rate and temperature, AC/glycol mixture flow rate, and AC concentration. Varying these parameters permits mapping the performance of the system under different conditions.</div></div>
Fundamental Characteristics of Tsunami and Tsunami Disaster due to The 2011 off the Pacific Coast of Tohoku Earthquake (2012)

A undersea earthquake with a magnitude of 9.0 "The 2011 off the Pacific Coast of Tohoku earthquake" took place off the Pacific coast of Japan at 14:46 JST (5:46 UTC) on March 11, 2011. A massive tsunami caused by the earthquake struck the Pacific side of Japan, especially the coasts of Aomori, Iwate and Miyagi prefectures, resulting in a cataclysmic disaster "East Japan Great Earthquake Disaster (Higashi Nihon Daishinsai in Japanese)". This paper describes the fundamental characteristics of Tsunami and the brief overview of the past huge tsunami disasters in Sanriku area. The tsunami damages of the East Japan Great Earthquake Disaster are, furthermore, reported on the base of the field survey, which was conducted from April 4 to 9, 2011 as a group of the 2011 Tohoku Earthquake Tsunami Joint Survey Group of Japan.
Elevated blood pressure and cardiac hypertrophy after ablation of the<i>gly96/IEX-1</i>gene (2005)

gly96/IEX 1 is a growth- and apoptosis-regulating, immediate early gene that is widely expressed in epithelial and vascular tissues. In vascular tissues, expression of the gene is induced by mechanical stretch, and overexpression of the gene prevents injury-induced vascular smooth muscle hypertrophy and neointimal hyperplasia. We now show that deletion of the gly96/IEX-1 gene in mice is associated with development of elevated blood pressure, cardiac hypertrophy, and diminished fractional shortening of the left ventricle. Systolic blood pressure in conscious male gly96/IEX-1-/- mice is 20-25 mmHg higher than in gly96/IEX-1+/+ mice. Serum and/or urine concentrations of sodium, potassium, creatinine, angiotensin II, corticosterone, aldosterone, epinephrine, norepinephrine, prostaglandin E2, thromboxane B2, prostaglandin-6-keto-1alpha, nitrites and nitrates, cAMP, and cGMP are normal in gly96/IEX-1-/- mice. Alterations in dietary sodium intake do not alter blood pressure in gly96/IEX-1-/- mice. Aortic mRNAs for endothelial nitric oxide synthase, guanylate cyclase-alpha, and cGMP kinase-1 are increased in gly96/IEX-1-/- mice. Treatment with Nomega-nitro-L-arginine methyl ester or L-arginine does not alter blood pressure in gly96/IEX-1-/- mice. Gly96/IEX-1-/- mice respond to infused sodium nitroprusside with decrements in blood pressure similar to those seen in wild-type littermate mice. In contrast to gly96/IEX-1 transgenic mice that have abnormalities in immune function, gly96/IEX-1-/- mice have normal lymphoid tissue architecture and a normal complement of T and B cells in lymphoid tissues. Ablation of the gly96/IEX-1 gene results in hypertension and cardiac hypertrophy, suggesting a novel role for this gene in cardiovascular physiology.
Elementary Risks: Bridging Operational and Strategic Security Realms (2015)

Risk management is widely used in order to evaluate and treat prominent risks for organizations. Such models are rather organizational (business-aware) than technical, and enable security officers to manage risks on the long run. However, both ICT systems and threat landscape do not cease to evolve, and dynamic cyber security management becomes paramount to address potential breaches. The operational security management is based on technical processes, executed by administrators who are not necessarily aware of organization's business and strategic aspects. This gap between technical and organizational levels renders traditional risks assessment methods cumbersome and obsolete. In this paper, we propose a novel concept of Elementary Risk (ER) that represents a quantum of risk for an organization. Composite Risks (CRs) are then calculated and presented for the security officer. CR enables dynamic calculation of organizational risk posture while considering the system's state. Moreover, ER and CR enable capture the contribution of technical elements (e.g. vulnerability, server) or security measures (e.g. patch, firewall rule) to the overall risk profile of the organization.
Isolated fungal cellulose terminal domains and a synthetic minimum analogue bind to cellulose (1989)

The cellulose‐binding properties of the highly conserved terminal region which is common to several fungal cellulases were studied. Domains were prepared by proteolytic cleavage of Trichoderma reesei CBH1 and the corresponding enzyme from Sporotrichum pulverulentum , and a peptide corresponding to residues 462–497 (the C‐terminal part) of Trichoderma CBH1 was synthesized. The three peptides showed similar binding behavior, whereas reduced and S ‐carboxymethylated T. reesei fragment was inactive. This region thus appears to serve as an independent functional domain in which the C‐terminal part is responsible for the binding, which in turn requires an intact three‐dimensional structure.
Morphological phenotypes of acute leukaemias in north eastern Nigeria (2000)

The frequencies of morphological phenotypes of 95 cases of acute leukaemias (AL) diagnosed during 1995-
 at the University of Maiduguri Teaching Hospital ([ TMTH) were analysed. Acute myeloid leukaemia (AML), predominantly seen in adults (age?_l5 years), was diagnosed in 53 cases out of which 16 cases (30.2%), 27 cases (50.9%) and 10 cases (18.9%) were of M1, M2 and Jvf3 morphological subtypes re,,pectivelv. Acute Lymphoblastic Leukaemia (ALL), predominantly seen in children (age< 15 years) was diagnosed in -12 cases out (){which 9 cases (21:4%), 27 cases (64.3%) and 6 cases (14.3%) were of L1, L2 and L3 subtypes respectivelv. The overall higher frequency of AML (55.8%) relative to ALL (44.2%) may be due to the current economic difficulties and can be
 to change in the future in favour of ALL if the standard of living of the general population is improved.
Expression and purification of PprI protein from D.radiodurans R1 in escherichia coli (2011)

In order to express and purify PprI protein from D.radiodurans R1 in E.coli,the full length of pprI gene was gained by PCR amplification using pCMV-HA-pprI as a template.The gene segment was inserted into vec-tor pET-28a after digested by two restriction endonucleases Nco I and EcoR I.Then the recombinant vector pET-28a-His-pprI was transfected into E.coli BL21(DE3) RP.The PprI protein expression was induced by IPTG and the fusion protein was confirmed by SDS-PAGE and Western blotting.The expressive conditions of the protein such as E.coli' A600,concentration of IPTG,time and temperature of culture,were optimized.Finally the fusion protein was purified by Ni-NTA His Bind Resins and molecule boult.The experimental results show the fusion protein con-firmed by Western blotting is 6×His-PprI and its molecular weight is 37 kDa.The ladders of PprI protein at molecular weight 37 kDa were different due to difference of the PprI protein expression conditions in E.coli.The PprI protein exists both in supernatant and precipitation.The concentration of purified protein is about 0.15 mg/mL which was measured by BCA method.It is concluded that the recombinant plasmid pET-28a-His-pprI is constructed and the PprI fusion protein is expressed and purified.The results lay a solid foundation for studying the radio-resistance and im-munity of PprI protein.
Aqueous Solubility of Salts at High Temperatures. II. The Ternary System Na<sub>2</sub>CO<sub>3</sub>—NaHCO<sub>3</sub>—H<sub>2</sub>O from 100 to 200° (1934)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAqueous Solubility of Salts at High Temperatures. II. The Ternary System Na2CO3—NaHCO3—H2O from 100 to 200°William F. Waldeck, George Lynn, and Arthur E. HillCite this: J. Am. Chem. Soc. 1934, 56, 1, 43–47Publication Date (Print):January 1, 1934Publication History Published online1 May 2002Published inissue 1 January 1934https://pubs.acs.org/doi/10.1021/ja01316a013https://doi.org/10.1021/ja01316a013research-articleACS PublicationsRequest reuse permissionsArticle Views253Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A novel adipokine CTRP1 stimulates aldosterone production (2008)

Complement-C1q TNF-related protein 1 (CTRP1), a member of the CTRP superfamily, is expressed at high levels in adipose tissues of obese Zucker diabetic fatty (fa/fa) rats, and CTRP1 expression is induced by proinflammatory cytokines, including TNF-alpha and IL-1beta. In the present study, we investigated stimulation of aldosterone production by CTRP1, since it was observed that CTRP1 was specifically expressed in the zona glomerulosa of the adrenal cortex, where aldosterone is produced. Increased aldosterone production by CTRP1 in cells of the human adrenal cortical cell line H295R was dose-dependent. Expression levels of aldosterone synthase CYP11B2 were examined to investigate the molecular mechanisms by which CTRP1 enhances the production of aldosterone. The expression of CYP11B2 was greatly increased by treatment with CTRP1, as was the expression of the transcription factors NGFIB and NURR1, which play critical roles in stimulation of CYP11B2 gene expression. It was also revealed that angiotensin II-induced aldosterone production is, at least in part, mediated by the stimulation of CTRP1 secretion, not by the increase of CTRP1 mRNA transcription. In addition, the levels of CTRP1 were significantly up-regulated in hypertensive patients' serum. As CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension.
Real-time globally consistent 3D grid mapping (2017)

For path planning of mobile robots in complex unknown three-dimensional (3D) environments, an accurate 3D volumetric representation of the environment is usually required. In this paper, we present a novel method to produce globally consistent 3D grid maps in real-time, through a grid-map update strategy and an efficient data structure. We transform point clouds into the world frame provided by a visual SLAM module, then process them by the grid mapping module to produce globally consistent 3D grid maps. Experimental results in an indoor scenario demonstrate that our approach is able to update the 3D grid map efficiently and can cope with loop closures while operating in real-time.
Manganese Complexes of Curcumin Analogues: Evaluation of Hydroxyl Radical Scavenging Ability, Superoxide Dismutase Activity and Stability towards Hydrolysis (2004)

In order to improve the antioxidant property of curcumin and its analogue, diacetylcurcumin, manganese was incorporated into the structures in order to enhance superoxide dismutase (SOD) activity. Manganese (Mn) complexes of curcumin (CpCpx) and diacetylcurcumin (AcylCpCpx) were synthesized and firstly investigated for SOD activity and hydroxyl radical (HO*) scavenging ability. SOD activity was evaluated by both the nitroblue tetrazolium (NBT) reduction assay and electron paramagnetic resonance (EPR) with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as a spin trapping agent. CpCpx and AcylCpCpx inhibited the NBT reduction and decreased the DMPO/OOH adduct much greater than corresponding antioxidants or ligands, with IC50 values of 29.9 and 24.7 microM (NBT), and 1.09 and 2.40 mM (EPR), respectively. For EPR, potassium superoxide (KO2) was used as a source of O2- where qualitative results suggested that CpCpx and AcylCpCpx were SOD mimics, which catalyze the conversion of O2- to dioxygen and hydrogen peroxide (H2O2). Additionally, CpCpx and AcylCpCpx exhibited the great inhibition of DMPO/OH adduct formation with an IC50 of 0.57 and 0.37mM, respectively, which were comparable to that of curcumin (IC50 of 0.64 mM), indicating that both Mn complexes are also an effective HO* scavenger. The stability against hydrolysis in water, various buffers and human blood/serum was carried out in vitro. It was found that both Mn complexes were pH and salt concentration dependent, being more stable in basic pH. In the human blood/serum test, CpCpx was more stable against hydrolysis than AcylCpCpx with about 10 and 20% of free Mn2+ releasing, respectively.
Fast IP table lookup and memory reduction (2002)

One of the time-consuming tasks in IP4 packet processing is maximum sequence matching. Fast routing requires tens of millions of routing lookups to be performed in one second. This paper describes an implementation of IP table lookup. The implementation is intended as part of the cord of an OC-192 (10 Gbps) and OC-768 (40 Gbps) rate packet processor. One key element is a memory reduction technique that applies to all lookup algorithms. For algorithms with similar complexity as the one described in the paper, the improvement in terms of memory reduction is about 20%-30%.
The DAU allele cluster of the RHDgene (2002)

Variant D occurs frequently in Africans. However, considerably less RHD alleles have been described in this population compared with Europeans. We characterized 5 new RHD alleles, dubbed DAU-0 to DAU-4, that shared a T379M substitution and occurred in a cDe haplotype. DAU-1 to DAU-4 were detected in Africans with partial D phenotypes. They harbored one and 2 additional missense mutations, respectively, dispersed throughout the RhD protein. An anti-D immunization was found in DAU-3. DAU-0 carrying T379M only was detected by screening European blood donors and expressed a normal D phenotype. Within the phylogeny of the RHD alleles, DAU formed an independent allele cluster, separate from the DIVa, weak D type 4, and Eurasian D clusters. The characterization of the RH phylogeny provided a framework for future studies on RH alleles. The identification of the DAU alleles increased the number of known partial D alleles in Africans considerably. DAU alleles may be a major cause of antigen D variability and anti-D immunization in patients of African descent.
Analyzing Computer Programming Job Trend Using Web Data Mining (2014)

An international association advancing the multidisciplinary study of informing systems. Founded in 1998, the Informing Science Institute (ISI) is a global community of academics shaping the future of informing science.
Reinforcing language model for speech translation with auxiliary data (2009)

Language model domain adaption usually uses a large quantity of auxiliary data in different genres and domains. It has mostly been relying on scoring functions for selection and it is typically independent of intended applications such as machine translation. In this paper, we present a novel domain adaptation approach that is directly motivated by the need of translation engine. We first identify interesting phrases by examining phrase translation tables, and then use those phrases as anchors to select useful and relevant sentences from general domain data, with the goal of improving domain coverage or providing additional contextual information. The experimental results on Farsi to English translation in military force protection domain and Chinese to English translation in travel domain show statistical significant gain using the reinforced language models over the baseline.
천수 및 수로 운항 시 선박의 측벽효과 (2014)

선박이 천수 및 수로를 운항하는 경우, 바닥과 측벽의 영향으로 인해 선체침하 및 비대칭적인 힘이 선체 주위에 발생하여 바닥이나 다른 선박 혹은 수로의 벽에 충돌하는 현상이 발생한다. 특히, 수로가 많은 유럽이나 북미를 운항하는 해운회사와 항해사들은 선박의 충돌을 방지하기 위해서 중요한 문제로 다루고 있다. 본 연구에서는 선박의 안전한 항해를 위해 수치해석을...
Influence of the 5‐HT<sub>2C</sub> receptor antagonist SB242,084 on behaviour produced by the 5‐HT<sub>2</sub> agonist Ro60‐0175 and the indirect 5‐HT agonist dexfenfluramine (2001)

Ro60-0175 has been described as a selective agonist at the 5-HT(2C) receptor, yet it has only 10- fold higher affinity at the 5-HT(2C) compared to the 5-HT(2A) subtype, and equivalent affinity for the 5-HT(2B) receptor. The selective 5-HT(2C) receptor antagonist SB242,084 (0.5 mg kg(-1) i.p.), blocked the hypoactivity and penile grooming induced by Ro60-0175 (1 mg kg(-1) s.c.). The combination of SB242,084 (0.5 mg kg(-1) i.p.) and Ro60-0175 (3 - 10 mg kg(-1)) produced a completely different pattern of behaviours including wet-dog shakes, hyperactivity and back muscle contractions. These latter effects were blocked by the selective 5-HT(2A) receptor antagonist MDL100,907 (0.5 mg kg(-1) i.p.), but not the 5-HT(2B) receptor antagonist SB215,505 (3 mg kg(-1) p.o.). The indirect 5-HT releaser/reuptake inhibitor dexfenfluramine (1 - 10 mg kg(-1) i.p.) produced a mild increase in locomotor activity, penile grooming, and occasional back muscle contractions and wet-dog shakes. Pre-treatment with SB242,084 (0.5 mg kg(-1)), blocked the incidence of penile grooming, and markedly potentiated both the dexfenfluramine-induced hyperactivity, the incidence of back muscle contractions, and to a lesser extent wet-dog shakes. Some toxicity was also evident in animals treated with dexfenfluramine (10 mg kg(-1))/SB242,084 (0.5 mg kg(-1)), but not in any other treatment groups. The hyperactivity and toxicity produced by the dexfenfluramine (10 mg kg(-1))/SB242,084 (0.5 mg kg(-1)) combination was replicated in a further study, and hyperthermia was also recorded. Both hyperthermia and toxicity were blocked by MDL100,907 (0.5 mg kg(-1)) but not SB215,505 (3 mg kg(-1)). An attenuation of the hyperlocomotor response was also observed following MDL100,907. These findings suggest that 5-HT(2C) receptor activation can inhibit the expression of behaviours mediated through other 5-HT receptor subtypes.