gebhart/patrepeval huggingface dataset:
Flow cytometry detection of platelet procoagulation activity and microparticles in patients with unstable angina treated by percutaneous coronary angioplasty and stent implantation. (2001)

Platelet activation is known to participate to the pathogenesis of acute coronary syndromes. Aminophospholipid exposure and microparticles shedding are hallmarks of full platelet activation and may account for the dissemination of prothrombotic seats. Using flow cytometry analysis of annexin V binding to externalized aminophospholipids, we followed platelet procoagulant activity (PPA) and platelet microparticles (PMP) shedding in venous and coronary whole blood samples from 30 patients with unstable angina before and after percutaneous coronary angioplasty (PTCA) and stent implantation. Baseline values of PPA and PMP were significantly more elevated in patients than in control subjects (p < 0.005). PMP percentage was significantly higher in coronary than in venous blood, and in coronary blood of patients with proximal instead of mid/distal lesions of coronary arteries. No enhancement of platelet reactivity to TRAP and collagen was induced by procedure. Whereas activated GpIIb-IIIa and P-selectin expression decreased 24 h and 48 h after procedure, PPA and PMP remained as elevated as before. Thus, flow cytometry is a reliable method for detection of fully activated platelets in whole blood samples. Annexin V binding analysis demonstrates the persistance of in vivo platelet activation, despite the use of antiaggregating agents.
Improvement of EMI Filter Performance With Parasitic Coupling Cancellation (2005)

In this paper, critical parasitic couplings in EMI filters are first identified. Based on the understanding of filter parasitics, methods are proposed to improve EMI filter performance by canceling critical couplings. A cancellation inductor is then integrated with capacitors to cancel the mutual coupling between two capacitors and the equivalent series inductance (ESL) of the integrated capacitor. The proposed method is applied to both rectangular and tubular capacitors. Two different integration approaches are also compared. Finally, prototypes are built and tested for both one-stage and two-stage EMI filters. Experimental results show the proposed mutual coupling cancellation technique can drastically improve EMI filter high frequency performance.
Soil profiles identify series: Basic soil surveys establish classifying characteristics and indicate selection of most efficient agricultural use (1957)

Differences in the surface 6' of soil—in structure, color, texture, reaction, content of salts or humus, mineralogical composition—usually have agricultural significance and separate soils into different series or identifying units of classification. Nearly 500 soil series have been identified in California.
Initial characterization of a prototype multi-crystal cylindrical SPECT system (1992)

A prototype single photon emission computed tomography (SPECT) has been constructed to demonstrate the performance of a multislice design for high-resolution brain imaging. The system consists of a stationary cylindrical detector comprised of multiple bars of NaI(Tl) scintillator, and a rotating collimator. The collimator consists of an assembly of multiholed modules arranged with a four quadrant symmetry. The collimator modules are individually focused for discrete sampling in the transverse plane but parallel collimated for continuous sampling in the axial direction. Fan beam sampling for each detector bar in the transverse plane is accomplished after a 360 degrees rotation of the collimator. An array of photomultiplier tubes coupled to the outside of the detector cylinder identifies the bar and the axial position along the bar for each detected event. The current performance of this prototype system has been evaluated. The tomographic images of resolution and anthromorphic phantoms demonstrated high image quality.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The development of malaria diagnostic techniques: a review of the approaches with focus on dielectrophoretic and magnetophoretic methods (2016)

The large number of deaths caused by malaria each year has increased interest in the development of effective malaria diagnoses. At the early-stage of infection, patients show non-specific symptoms or are asymptomatic, which makes it difficult for clinical diagnosis, especially in non-endemic areas. Alternative diagnostic methods that are timely and effective are required to identify infections, particularly in field settings. This article reviews conventional malaria diagnostic methods together with recently developed techniques for both malaria detection and infected erythrocyte separation. Although many alternative techniques have recently been proposed and studied, dielectrophoretic and magnetophoretic approaches are among the promising new techniques due to their high specificity for malaria parasite-infected red blood cells. The two approaches are discussed in detail, including their principles, types, applications and limitations. In addition, other recently developed techniques, such as cell deformability and morphology, are also overviewed in this article.
Prehistory of the Carson Desert and Stillwater Mountains: Environment, Mobility, and Subsistence in a Great Basin Wetland. Robert L. Kelly, with contributions by Virginia L. Butler, Linda Scott Cummings, Steven D. Grantham, Richard E. Hughes, Keith K. Katzer, Stephanie Livingston, David Rhode, Nancy D. Sharp, and Peter Wigand. 2001. University of Utah Press, Salt Lake City. University of Utah Anthropological Papers No. 123. vii + 325 pp., $45.00 (paper), ISBN 0-87480-672-0. (2004)

Prehistory of the Carson Desert and Stillwater Mountains: Environment, Mobility, and Subsistence in a Great Basin Wetland. Robert L. Kelly, with contributions by Virginia L. Butler, Linda Scott Cummings, Steven D. Grantham, Richard E. Hughes, Keith K. Katzer, Stephanie Livingston, David Rhode, Nancy D. Sharp, and Peter Wigand. 2001. University of Utah Press, Salt Lake City. University of Utah Anthropological Papers No. 123. vii + 325 pp., $45.00 (paper), ISBN 0-87480-672-0. - Volume 69 Issue 3
Cumulative Sum (<scp>CUSUM</scp>) Chart (2017)

Abstract The use of the cumulative sum (CUSUM) charting procedure in process monitoring is first described. The relationship between the CUSUM charting procedure and Wald's sequential probability ratio test is then explained. This is followed by three main approaches of determining the average run length. The strengths and weaknesses of the CUSUM charting procedure, with respect to the Shewhart charting procedure, are illustrated with simulated data sets. Various other aspects of the CUSUM chart are also discussed. These include estimation of process mean using the CUSUM, weighting of samples for signaling, fast initial response for a newly start‐up process, simultaneous CUSUM schemes, design of CUSUM chart, multivariate CUSUM schemes, and risk‐adjusted CUSUM charts.
Crystal structure of α-oxobenzeneacetatotris(triphenylphosphine)silver(I), [(C8H5O3)(C18H15P)3Ag] (1997)

Article Crystal structure of α-oxobenzeneacetatotris(triphenylphosphine)silver(I), [(C8H5O3)(C18H15P)3Ag] was published on December 1, 1997 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 212, issue 1).
Novel splicing and missense mutations in autosomal dominant polycystic kidney disease 1 (PKD1) gene: Expression of mutated genes (2000)

Autosomal dominant polycystic kidney disease (ADPKD) is a common disorder mostly characterized by cyst formation in kidney tubules. The majority of ADPKD cases is caused by mutations in the PKD1 gene, but no prevalent mutation has been reported. By heteroduplex analysis of the 3' single-copy region of the gene, we have searched for mutations in subjects from 40 ADPKD families of Northern Italy. Seven novel polymorphisms and three novel disease-associated mutations (R3718Q, L3851P and IVS45+56del25) were identified. Both missense mutations are located in the major extracellular loop of polycystin-1. The 25 bp deletion inside intron 45 did not affect 5' and 3' consensus splicing sites, but caused a 56 nucleotide out of frame-deletion due to activation of a cryptic 3' splice site in exon 46. The mutated RNA should produce a truncated polycystin 1 at the G binding peptide in the intracellular C-terminal end of the protein. RT-PCR analysis showed that the disease-associated mutations were present in transcribed sequences. In particular, RNA analysis of BHK cells transfected with PKD1 genomic DNA, including the deleted intron, showed that no normal transcript is produced by the deleted gene. This intronic mutation, found in a large pedigree, seems to be associated with a prevalence of cerebrovascular disease.
A quantum dot ratchet: Experiment and theory (1998)

Particles in a ratchet, that is, a potential without spatial inversion symmetry, can move in one direction even in the absence of macroscopic forces, provided that there is a source of energy. In this paper, a quantum ratchet, based on an asymmetric (triangular) quantum dot, is investigated experimentally and theoretically. We find that coherent electron transport through such a device depends on the sign of the applied voltage. In this way a net current can be obtained even when the applied ac voltage is zero on average. Strikingly, the direction of the current depends on the amplitude at which the quantum dot ratchet is rocked.
Growth and luminescence of the bacterium Xenorhabdus luminescens from a human wound (1989)

Xenorhabdus luminescens, a newly isolated luminous bacterium collected from a human wound, was characterized. The effects of ionic strength, temperature, oxygen, and iron on growth and development of the bioluminescent system were studied. The bacteria grew and emitted light best at 33 degrees C in a medium with low salt, and the medium after growth of cells to a high density was found to have antibiotic activity. The emission spectrum peaked at 482 nm in vivo and at 490 nm in vitro. Both growth and the development of luminescence in X. luminescens required oxygen and iron. The isolated luciferase itself exhibited a temperature optimum at about 40 degrees C; after purification by affinity chromatography, it showed two bands (52 and 41 kilodaltons) on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, indicative of an alpha and beta subunit structure. Reduced flavin mononucleotide (Km of 1.4 microM) and tetradecanal (Km of 2.1 microM) were the best substrates for the luciferase, and the first-order decay constant under these conditions at 37 degrees C was 0.79 s-1.
Predictive control of a vehicle convoy considering lane change behavior of the preceding vehicle (2015)

In this paper, a model predictive control approach is proposed for a vehicle convoy traveling on homogeneous highway. Specifically, the lane change behavior of a cut-in vehicle in front of the vehicle convoy is estimated and predicted for the predictive control of the leading vehicle in the convoy. In order to capture state differences of the preceding vehicle in different lane change manners, a cost function considering riding comfort and spacing safety is designed for the leading vehicle based on the free headway set ahead. The proposed cost function integrates trajectory differences of the cut-in vehicle, which makes the controller sensible to different lane change manners. The space keeping and velocity tracking performance of the controller is tested and compared with a conservative controller under different lane change behavior of the cutin vehicle. Furthermore, the control effects on the spacing and velocity of the followers in the convoy are analyzed. The simulation results show that the controller considering lane change behavior difference has smaller velocity and spacing fluctuations dealing with lane change disturbance.
Sur les acides nitro‐5‐ et nitro‐3‐dichloro‐2,4‐benzoïques (1957)

Abstract Par nitration de l'acide dichloro‐2,4‐benzoïque, nous avons isolé à côté, de l'acide nitro‐5‐dichloro‐2,4‐benzoïque une petite quantité d'acide nitro‐3‐dichloro‐2, 4‐benzoïque.
Enhanced cooling in mono-crystalline ultra-thin silicon by embedded micro-air channels (2015)

In today’s digital world, complementary metal oxide semiconductor (CMOS) technology enabled scaling of bulk mono-crystalline silicon (100) based electronics has resulted in their higher performance but with increased dynamic and off-state power consumption. Such trade-off has caused excessive heat generation which eventually drains the charge of battery in portable devices. The traditional solution utilizing off-chip fans and heat sinks used for heat management make the whole system bulky and less mobile. Here we show, an enhanced cooling phenomenon in ultra-thin (&gt;10 μm) mono-crystalline (100) silicon (detached from bulk substrate) by utilizing deterministic pattern of porous network of vertical “through silicon” micro-air channels that offer remarkable heat and weight management for ultra-mobile electronics, in a cost effective way with 20× reduction in substrate weight and a 12% lower maximum temperature at sustained loads. We also show the effectiveness of this event in functional MOS field effect transistors (MOSFETs) with high-κ/metal gate stacks.
Arabidopsis cpSRP54 regulates carotenoid accumulation in Arabidopsis and Brassica napus (2012)

An Arabidopsis thaliana mutant, cbd (carotenoid biosynthesis deficient), was recovered from a mutant population based on its yellow cotyledons, yellow-first true leaves, and stunted growth. Seven-day-old seedlings and mature seeds of this mutant had lower chlorophyll and total carotenoids than the wild type (WT). Genetic and molecular characterization revealed that cbd was a recessive mutant caused by a T-DNA insertion in the gene cpSRP54 encoding the 54 kDa subunit of the chloroplast signal recognition particle. Transcript levels of most of the main carotenoid biosynthetic genes in cbd were unchanged relative to WT, but expression increased in carotenoid and abscisic acid catabolic genes. The chloroplasts of cbd also had developmental defects that contributed to decreased carotenoid and chlorophyll contents. Transcription of AtGLK1 (Golden 2-like 1), AtGLK2, and GUN4 appeared to be disrupted in the cbd mutant suggesting that the plastid-to-nucleus retrograde signal may be affected, regulating the changes in chloroplast functional and developmental states and carotenoid content flux. Transformation of A. thaliana and Brassica napus with a gDNA encoding the Arabidopsis cpSRP54 showed the utility of this gene in enhancing levels of seed carotenoids without affecting growth or seed yield.
A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644. (1988)

Early afterdepolarizations (EADs) are one mechanism proposed to cause certain cardiac arrhythmias. We studied the effect of the Ca2+ channel agonist Bay K 8644 (1 x 10(-8) to 5 x 10(-5) M) on normally polarized sheep and canine cardiac Purkinje fiber short segments. EADs occurred with higher Bay K 8644 concentrations and had an average take-off potential of -34 mV. The initiation of EADs was preceded by lengthening of action potential duration and flattening of the plateau. Induction of EADs with Bay K 8644 was enhanced by low stimulation frequencies, lowering of [K]o, addition of tetraethylammonium chloride, or application of depolarizing constant current pulses during the plateau. EADs were abolished by increasing stimulation frequency, raising [K]o, the addition of tetrodotoxin, lidocaine, ethmozin, verapamil, and nitrendipine, or application of repolarizing constant current pulses. Using current pulses to modify the action potential plateau, a steep inverse relationship was found between the EAD peak voltage and its take-off potential, and EADs could be initiated over only a narrow range of take-off potentials. Thus, interventions that suppressed EADs shortened action potential duration or shifted the plateau away from the voltage range needed to initiate EADs. These observations suggest that mechanisms dependent on both time and voltage underlie EADs, and provide a unifying hypothesis for the induction of the EADs. We propose that induction of EADs requires 1) lengthening of action potential duration within a plateau voltage range where 2) recovery from inactivation and reactivation of an inward current possibly carried through Ca2+ channels can occur.
Time-scale modification of audio signals with combined harmonic and wavelet representations (2002)

We propose a new time-scale modification method for high quality audio signals. Our approach strives to preserve pitch and timbre. In our method, the signal is represented as the sum of sinusoidal components and a residual (edges and noise). The decomposition is computed via a combined harmonic and wavelet representation. Time-scaling is performed on the harmonic components and residual components separately. The harmonic portion is time-scaled by demodulating each harmonic component to DC, interpolating and decimating the DC signal, and remodulating each component back to its original frequency. The residual portion is time-scaled by preserving edges and relative distances between the edges while time-scaling the stationary (noise) components between the edges.
Replacement of methylthio functions on aromatic heterocycles by hydrogen, alkyl and aryl groups via nickel-induced Grignard reactions (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReplacement of methylthio functions on aromatic heterocycles by hydrogen, alkyl and aryl groups via nickel-induced Grignard reactionsErnest Wenkert, James M. Hanna Jr., Michael H. Leftin, Enrique L. Michelotti, Kevin T. Potts, and Douglas UsiferCite this: J. Org. Chem. 1985, 50, 7, 1125–1126Publication Date (Print):April 1, 1985Publication History Published online1 May 2002Published inissue 1 April 1985https://pubs.acs.org/doi/10.1021/jo00207a044https://doi.org/10.1021/jo00207a044research-articleACS PublicationsRequest reuse permissionsArticle Views799Altmetric-Citations68LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Prediction of Molar Extinction Coefficients of Proteins and Peptides Using UV Absorption of the Constituent Amino Acids at 214 nm To Enable Quantitative Reverse Phase High-Performance Liquid Chromatography−Mass Spectrometry Analysis (2007)

The molar extinction coefficients of 20 amino acids and the peptide bond were measured at 214 nm in the presence of acetonitrile and formic acid to enable quantitative comparison of peptides eluting from reversed-phase high-performance liquid chromatography, once identified with mass spectrometry (RP-HPLC-MS). The peptide bond has a molar extinction coefficient of 923 M(-1) cm(-1). Tryptophan has a molar extinction coefficient that is approximately 30 times higher than that of the peptide bond, whereas the molar extinction coefficients of phenylalanine, tyrosine, and histidine are approximately six times higher than that of the peptide bond. Proline, as an individual amino acid, has a negligible molar extinction coefficient. However, when present in the peptide chain (except at the N terminus), it absorbs approximately three times more than a peptide bond. Methionine has a similar molar extinction coefficient as the peptide bond, while all other amino acids have much lower molar extinction coefficients. The predictability of the molar extinction coefficients of proteins and peptides, calculated by the amino acid composition and the number of peptide bonds present, was validated using several proteins and peptides. Most of the measured and calculated molar extinction coefficients were in good agreement, which shows that it is possible to compare peptides analyzed by RP-HPLC-MS in a quantitative way. This method enables a quantitative analysis of all peptides present in hydrolysates once identified with RP-HPLC-MS.
Dietary fiber in human nutrition (1975)

In recent years there has been a reawakening of interest in the effect of plant fibers on human nutrition. This has been spurred by the epidemiological work of Burkitt, Painter, Walker, and Trowell and by some laboratory and clinical studies performed by Eastwood, Kritchevsky, and other investigators. “Fiber” is the collective term used to identify the various polysaccharides and lignin fractions of foods that are not hydrolyzed by the enzymes of the digestive system (but that are, or might be, hydrolyzed by intestinal microorganisms). To some investigators, “fiber” means all these polymers plus the other components of the cell wall (cutins, minerals, etc.) intimately involved in the fiber function. The combination of epidemiological studies and laboratory research has lead to various hypotheses that have linked “low fiber diets” in Western countries to various chronic diseases. Some of the diseases mentioned are major chronic afflictions of the developed nations (e.g., colon cancer and CHD), and the possible interrelation of fiber in the diet with the etiology of these syndromes has stirred a great deal of interest.
The Temperature Dependence of Rare‐Earth Activated Garnet Phosphors: II . A Comparative Study of Ce3+, Eu3+, Tb3+, and Gd3+ in (1979)

Relative cathodoluminescence quantum intensity measurements made on crystals containing a series of concentrations of each of the ions Ce3+, Eu3+, Tb3+, and Gd3+ are reported as a function of temperature. For the first three of these activator ions the CL intensity increases with temperature, although the efficiency of Eu3+ luminescence rises much more steeply at low temperatures than Ce3+ and Tb3+. The temperature dependence of Gd3+ is very different, the luminescence intensity quenching rapidly above 120°K. The experimental results are rationalized in terms of proposed differences in the form of the impurity potential for each of these ions. Previously detected lattice defect levels are now assigned as hole trapping centers. Ce3+ and Tb3+ form competitive hole trapping centers. Eu3+, however, is found to be a stable electron‐attractive center. The potential for Gd3+ is predicted to be weak and this center forms no stable bound state. It is possible that long‐range energy transfer from the lattice defect level plays some role in Gd3+ excitation.