gebhart/patrepeval huggingface dataset:
Proteolytic activity of Candida albicans: action on human salivary proteins (1978)

The susceptibility of human salivary proteins to degradation by Candida albicans was studied. The organism was cultivated in either whole-salivary supernatant or parotid fluid, both of which were supplemented with glucose (0.1%). The culture pH's were at, or above, neutrality. After growth, the culture supernatant solutions were examined by polyacrylamide gel electrophoresis for alterations in their profiles of salivary proteins. No evidence of proteolysis of whole-saliva or parotid fluid proteins was found. Salivary proteins, however, are susceptible to degradation by preparations of C. albicans protease. Candida protease was incubated with parotid fluid adjusted to several pH values. After incubation the reaction mixtures were subjected to polyacrylamide gel electrophoresis. Extensive degradation of parotid proteins was found at pH 4, very slight proteolysis at pH 5, and no degradation at pH 6 or 7. No selectivity in proteolysis of the several parotid proteins was noted. These results indicate that C. albicans protease is strictly dependent upon low (ca. 4) pH for activity on salivary proteins. Furthermore, it is suggested that due to the pH requirements of the enzyme, it is unlikely to be of major significance to the pathogenesis of Candida-induced oral inflammatory lesions.
[Anaerobic fermentation biohydrogen production from molasses, starch and milk wastewaters]. (2004)

Research of anaerobic fermentation biohydrogen production from molasses, starch and milk wastewater in CSTR was conducted. The theoretic possibility of biohydrogen production from three kinds of organic materials and the hydrogen producing stability was also discussed. The results indicated that molasses and starch wastewaters are preferable feeds for anaerobic biohydrogen fermentation. The hydrocarbon is the optimal feed in the main three kinds of organic materials at present time. The sugars which dissolving better are preferable materials for biohydogen production than starch at present, but the starch is better than sugars for biohydrogen production in the future if the conditions could been controlled good. The niches are variety along with the different of feeds. The optimal pH values of stability operational controlling is 4.5 +/- 0.3 for sugars wastewater and 4.0 +/- 0.2 for starch wastewater. The ORP value must lower than -220 mV and the optimal value is about -300 mV. The milk wastewater is not the suitable biohydrogen production material in CST reactor.
Human action recognition (2014)

In the recent years, various computer vision application opportunities such as human action recognition have emerged. It is important that the actions are efficiently classified and identified from video sequences for video analysis. As detecting and understanding such actions would lead to many helpful applications like assisting the sick and security related\n\n\n\nsurveillance applications. To ensure this, key motion features are extracted using the optical flow algorithm. In order to help identify such actions from features, classification algorithms such as Multilayer perceptron (MLP) and Support Vector Machines (SVM) are needed. This report will focus on Meta-cognitive Radial Basis Function Network and Projection based learning (PBL-McRBFN) algorithm for classification of human actions. McRBFN consists\n\n\n\nof two components, cognitive and meta-cognitive. The cognitive component represents knowledge and the meta-cognitive component enables the measured acquisition of knowledge. Meta-cognitive learning emulates human learning by deciding on what-to-learn, when-to-learn and how-to-learn which helps capture knowledge efficiently. The PBL algorithm computes the optimal output weights with the least computation effort in the cognitive component. Using classification algorithms such as LibSVM, Native Bayes and Bayes Net, we are able to present the decision making abilities by comparing the overall and average efficiencies with PBL-McRBFN. To evaluate performance efficiency of the\n\n\n\nalgorithms mentioned above, Weizmann and KTH datasets from the human action depositories are used as benchmarks. The statistical results have shown that PBL-McRBFN has performed better than the other classifiers as the results reported in the literature review.
Un estudio del fenómeno de la autoridad en niños de sectores de pobreza (2010)

This work is the result of a research study that tries to identify and describe the elements and dynamics that structure the concept of authority children have. Such concept is fundamental due to the incidence it has upon the development of the children's character, involving both their individual and social aspects, which structures since their earliest interactions. In this same context, authority is conceptualized from values, ideas and practices that children have apprehended in the earliest opportunities they had to socialize: family and school. A descriptive scheme was used as methodological strategy to carry out this study. Information was collected using the technique of semi-structured interviews, which were validated by expert judges. The sample object of study was formed by 1000 children aged 4-7, from poverty-stricken areas, and who lived with both parents
A Tone-Mapping Technique Based on Histogram Using a Sensitivity Model of the Human Visual System (2017)

High-dynamic-range (HDR) images require tone mapping to be displayed properly on lower dynamic range devices. In this paper, a tone-mapping algorithm that uses histogram of luminance to construct a lookup table (LUT) for tone mapping is presented. Characteristics of the human visual system (HVS) are used to give more importance to visually distinguishable intensities while constructing the histogram bins. The method begins with constructing a histogram of the luminance channel, using bins that are perceived to be uniformly spaced by the HVS. Next, a refinement step is used, which removes the pixels from the bins that are indistinguishable by the HVS. Finally, the available display levels are distributed among the bins proportionate to the pixels counts thus giving due consideration to the visual contribution of each bin in the image. Quality assessment using both quantitative evaluations and user studies suggests that the presented algorithm produces tone-mapped images that are visually pleasant and preserve details of the original image better than the existing methods. Finally, implementation details of the algorithm on GPU for parallel processing are presented, which could achieve a significant gain in speed over CPU-based implementation.
In Vitro Gene Transfer Efficacies of<i>N</i>,<i>N</i>-Dialkylpyrrolidinium Chlorides:  A Structure−Activity Investigation (2005)

Inspired by the previously reported superior gene transfer efficacies of amine headgroup-containing cationic lipids to their hydroxy counterparts, in the present structure-activity investigation we have compared the relative in vitro gene transfer efficacies of eight newly synthesized structural analogues of our previously reported lipids 1-4, namely the four 3,4-diaminopyrrolidinium chloride structural analogues (lipids 9-12, Chart 1) and the N-BOC-protected precursors of these amine analogues (lipids 5-8, Chart 1) with our previously reported lipids 1-4 (Chart 1) in five cultured cell lines. In contrast to the above-mentioned earlier reports, except for the superior or comparable transfection efficacies of the diaminopyrrolidinium lipids with distearyl and stearyloleyl chains (lipid 11 and 12 respectively, Chart 1) in MCF-7 and HEK293T cells, the relative transfection efficacies of the other diamino analogues were found to be much lower than their dihydroxy counterparts. The results of the DNase I sensitivity assays indicate that enhanced degradation of DNA associated with lipids 9-12 by cellular DNase I might play an important role behind their seriously compromised transfection efficacies. In addition, the present structure-activity investigation revealed a strikingly cell tropic transfection behavior of lipid 6 (Chart 1). While lipids 5, 7, and 8 were found to be either poor or essentially incompetent in transfecting all the five cells, lipid 6 was remarkably efficacious in transfecting kidney cells (COS-1 and HEK293T cells) at lipid:DNA charge ratios 3:1 and 1:1 when used in combination with equimolar amounts of DOPE and DOPC.
A memory-based artificial neural network (1991)

The authors propose a novel memory-based architecture of artificial neural networks, namely, the method of multiplexing the memory table for approximate realization of the sigmoidal function. The lack of precision is compensated by the host computer (which serves as the development tool) when the system works in the learning stage. Moreover, the weight of a neuron can be changed smoothly since the memory is modified to be writable in broadcasting for a selected address bit. As a result, the learning can be made fast with a relatively low cost. The execution time for the real input is very fast, especially when the input is binary, because the neural operation is achieved only by once table-looking. Implementation of the proposed architecture is presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Thymus transplantation for complete DiGeorge syndrome: European experience (2017)

This study confirms the previous reports that thymus transplantation can reconstitute T cells in patients with cDGS but with frequent autoimmune complications in survivors.
miR-133a suppresses cell proliferation, migration and invasion in human lung cancer by targeting MMP-14 (2013)

Lung cancer is the leading cause of cancer‑related mortality worldwide. Over half of lung cancer cases are diagnosed after metastasis, for which the median survival time is approximately 8 months. microRNAs (miRNAs), which are a class of single‑stranded endogenous non‑coding RNAs, are likely to be involved in most biological processes. miR‑133 plays roles in cardiac development and disease, and recent studies showed that miR‑133 is downregulated in various human malignancies, such as bladder and lung cancer. However, its detailed role in the processes of cancer remains to be determined. In the present study, we found that in the lung cancer cell lines A549 and NCI‑H1299 overexpression of miR‑133a suppressed cell proliferation, migration and invasion. The miR‑133a‑induced suppression of cell migration and invasion can be reversed by miR‑133a‑specific inhibitor. According to the mRNA sequence, matrix metalloproteinase (MMP)‑14, which is an important regulator of metastasis, is a predicted target of miR‑133a. This was confirmed by dual luciferase reporter assay. Moreover, miR‑133a overexpression decreases the mRNA and protein levels of MMP‑14. Collectively, these results suggest that miR‑133a may inhibit lung cancer metastasis by targeting MMP‑14 and may be used as an anti‑metastatic therapy in lung cancer patients.
In vivo selection to improve gene therapy of hematopoietic disorders. (2002)

Successful gene therapy of hematopoietic disorders lacking intrinsic natural selection for genetically corrected cells will require efficient ex vivo gene transfer into autologous hematopoietic stem cells (HSCs). For these diseases, currently available gene transfer methodologies are unlikely to result in therapeutic numbers of corrected HSCs, especially in the setting of minimal recipient conditioning. A strategy to increase the numbers of genetically corrected HSCs in an individual is therefore highly desirable. One approach to overcome the barrier of limiting numbers of genetically corrected cells is to endow them with a competitive advantage conferred by inclusion of a 'selectable' gene in the therapeutic vector. Herein, we review recent progress in the development of in vivo selection systems, which hold promise in facilitating successful gene therapy.
A Downstream Mediator in the Growth Repression Limb of the Jasmonate Pathway (2007)

Wounding plant tissues initiates large-scale changes in transcription coupled to growth arrest, allowing resource diversion for defense. These processes are mediated in large part by the potent lipid regulator jasmonic acid (JA). Genes selected from a list of wound-inducible transcripts regulated by the jasmonate pathway were overexpressed in Arabidopsis thaliana, and the transgenic plants were then assayed for sensitivity to methyl jasmonate (MeJA). When grown in the presence of MeJA, the roots of plants overexpressing a gene of unknown function were longer than those of wild-type plants. When transcript levels for this gene, which we named JASMONATE-ASSOCIATED1 (JAS1), were reduced by RNA interference, the plants showed increased sensitivity to MeJA and growth was inhibited. These gain- and loss-of-function assays suggest that this gene acts as a repressor of JA-inhibited growth. An alternative transcript from the gene encoding a second protein isoform with a longer C terminus failed to repress jasmonate sensitivity. This identified a conserved C-terminal sequence in JAS1 and related genes, all of which also contain Zim motifs and many of which are jasmonate-regulated. Both forms of JAS1 were found to localize to the nucleus in transient expression assays. Physiological tests of growth responses after wounding were consistent with the fact that JAS1 is a repressor of JA-regulated growth retardation.
Distributed Service Discovery with Guarantees in Peer-to-Peer Networks using Distributed Hashtables. (2005)

Abstract — In this paper we propose a protocol for service discovery in decentralized environments. Our protocol guarantees that service descriptions can be found by any node in the network. It is meant to be used by applications which cannot afford central components, e.g. due to ad-hoc formation. The protocol makes use of the structured overlay network Chord. Chord has logarithmic performance for looking up keys with respect to the number of nodes and guarantees to retrieve any entry stored in the network. This would not be possible in an unstructured overlay network without flooding the whole network. Service descriptions are decomposed into portions which can be efficiently distributed and retrieved. Though this implies additional costs for publishing of service descriptions, it improves efficiency of lookup operations. We implemented a Java prototype of our protocol as a proof of concept based on TCP/IP.
Comparison of Four Embolic Materials at Uterine Artery Embolization by Using Postprocedural MR Imaging Enhancement (2009)

Patients treated with Bead Block or Contour SE demonstrated a reduced degree of infarction at follow-up MR imaging compared with patients treated with Contour or Embosphere.
Changing the game: how video games are transforming the future of business (2009)

Part I: Introduction 1 Chapter 1: An Introduction to Games, and Why They Matter 3 Part II: Games and Customers 33 Chapter 2: Advertising In and Around Games 37 Chapter 3: Advergames 55 Chapter 4: Adverworlds, Second Life, and Blurred Reality 75 Part III: Games and Employees 97 Chapter 5: Better Employees through Gaming 101 Chapter 6: Three Skills for an Interconnected World 115 Chapter 7: Games and Recruiting 139 Part IV: Games and the Future of Business 155 Chapter 8: Games for Work, Games at Work 157 Chapter 9: User Innovation Communities 171 Chapter 10: Why Gamers are Better than Computers, Scientists, and Governments 187 Games Index 203 Index 207
Online statistical process control with NDE and computers (2003)

It is shown that, for statistical process control (SPC) using ultrasonic instruments for nondestructive evaluation (NDE) directly interfaced with a computer, a variable in every part can be measured at production line speeds and used in groups, typically of five, to generate points for control charts. The process control computer can then analyze the control chart (held in its memory and updated in real-time) to indicate out-of-control conditions. An indication can be produced in the time to manufacture from 5 to 40 parts, not in hours as with manual SPC. The computerized speed cannot be used directly because the statistics of control charts yields Type I errors (calling good production bad) of 1% probability per control chart point. However, an algorithm has been developed yielding an error probability of three parts in 100000. The algorithm is based on a Monte Carlo study of the statistics of control chart run rules. The Monte Carlo simulation is presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Highly efficient CMOS class E power amplifier for wireless communications (2002)

A novel high efficiency, low voltage CMOS class E power amplifier for wireless communications is presented. The power amplifier operating at 1.8 GHz is designed and simulated with a 0.6 /spl mu/m CMOS process. A two-stage power amplifier architecture with a band-rejection filter for first stage driver delivers 24.8 dBm of power to the 50 /spl Omega/ load with a power added efficiency greater than 73% at a supply voltage of 2.5 V.
Neutralization of SARS-CoV-2 Omicron variant by sera from BNT162b2 or Coronavac vaccine recipients (2021)

ABSTRACT Background The SARS-CoV-2 Omicron variant, designated as a Variant of Concern(VOC) by the World Health Organization, carries numerous spike protein mutations which have been found to evade neutralizing antibodies elicited by COVID-19 vaccines. The susceptibility of Omicron variant by vaccine-induced neutralizing antibodies are urgently needed for risk assessment. Methods Omicron variant strains HKU691 and HKU344-R346K were isolated from patients using TMPRSS2-overexpressing VeroE6 cells. Whole genome sequence was determined using nanopore sequencing. Neutralization susceptibility of ancestral lineage A virus and the Omicron, Delta and Beta variants to sera from 25 BNT162b2 and 25 Coronavac vaccine recipients was determined using a live virus microneutralization assay. Results The Omicron variant strain HKU344-R346K has an additional spike R346K mutation, which is present in 8.5% of strains in GISAID database. Only 20% and 24% of BNT162b2 recipients had detectable neutralizing antibody against the Omicron variant HKU691 and HKU344-R346K, respectively, while none of the Coronavac recipients had detectable neutralizing antibody titer against either Omicron isolates. For BNT162b2 recipients, the geometric mean neutralization antibody titers(GMT) of the Omicron variant isolates(5.43 and 6.42) were 35.7-39.9-fold lower than that of the ancestral virus(229.4), and the GMT of both omicron isolates were significantly lower than those of the beta and delta variants. There was no significant difference in the GMT between HKU691 and HKU344-R346K. Conclusions Omicron variant escapes neutralizing antibodies elicited by BNT162b2 or CoronaVac. The additional R346K mutation did not affect the neutralization susceptibility. Our data suggest that the Omicron variant may be associated with lower COVID-19 vaccine effectiveness.
Analysis on the clinicopathology characteristics and clinical significance of HIF-1α,VEGF and VEGF-C expression in thyroid carcinomas in Rizhao coastal district (2009)

Objective To study the elinieopathology characteristics and clinical significance of HIF-1α, VEGF and V EGF-C expression in papillary thyroid carcinoma(FTC) in Rizhao coastal district. Methods A statistic analysis was performed on materials of 253 cases thyroid carcinomas in two Hospitals in Rizhao area. HIF-1α,VEGF and VEGF-C expression were detected by immunohistochenical S-P method in 70 patients of PTC,64 patient s of thyroid adenoma(TA)and 70 patients of nodular goiter(NG). Results The thyroid carci-noma average biopsy ratio was 0. 63%. The total detection rate of thyroid carcinoma changed randomly. The ex-pression of HIF-1α,VEGF and VEGF-C in PTCs was higher than that in TAs and in NGs(P <0.05) and was higher in PTCs with lymph node metastasis than that without metastasis( P <0. 05 ). VEGF and VEGF-C expres-sion had a positive correlation with HIF-1α(P <0. 05). Conclusion The incidence of TC tends to increase af-ter 2004 in Rizhao coastal distric, the change in biopsy ratios may be related with the diagnosis levd markedly improved, the detection rate increased in Thyroid microearcinoma, and ingesting a great deal of iodine and HIF-1α, VEGF and VEGF-C expression significantly increased. These needed further study. 

Key words: 
Thyroid carcinoma;  Incidence;  Hypoxia inducible factor-1α;  Vascular endothelial growth factor
3D Applications for 3G Mobile Phones: Design, Development, Resource Utilization (2006)

The main issues that we deal during 3D application implementation for mobile phones are performance and resources limitations. Often we have to create the application for different mobile devices with various characteristics: performance, memory, screen size. In this case we have to utilize the created content for future easy usage. We purpose an approach which should allow developers to improve development process. The article also should help to choose the optimal development tool for 3D model creation and export to 2D/3D for mobile devices.
Combustion synthesis and luminescence properties of SrAl<sub>2</sub>O<sub>4</sub>:Eu<sup>2+</sup>,Dy<sup>3+</sup>,Tb<sup>3+</sup> phosphor (2007)

Eu(2+), Dy(3+) and Tb(3+) co-doped strontium aluminate phosphor with high brightness and long afterglow was synthesized by a combustion method, using urea as a reducer. The properties of SrAl(2)O(4):Eu(2+),Dy(3+),Tb(3+) phosphor with a series of initiating combustion temperatures, urea concentrations and boric acid molar fractions were investigated. The sample at initiating combustion temperature of 600 degrees C exhibited an intense emission peak at 513 nm, in which the phosphor existed as a single-phase monoclinic structure. The experimental results showed that the optimum ratio of urea is 2.0 times higher than theoretical quantities and that the suitable molar fraction of H(3)BO(3) is 0.08. The average particle size of the phosphor was 50-80 nm and its luminescence properties were studied systematically. Compared with SrAl(2)O(4):Eu(2+),Dy(3+) phosphor, the initial luminescence brightness improved from 2.50 candela (cd)/m(2) to 3.55 cd/m(2) and the long afterglow time was prolonged from 1290 s to 2743 s.
Arab herbal medicine. (2008)

Despite the great progress in modern medicine, traditional medicine has always been practised in the Arab-Islamic world. Cultural beliefs and practices often lead to self-care or home remedies in rural areas and consultation with traditional healers. Traditional therapies have been utilized by people in the Mediterranean region who have faith in spiritual healers, homeopaths or even many herbalists. These are the first choice for problems such as infertility, impotence, diabetes, obesity, epilepsy, psychosomatic troubles and many other diseases. The modern use of Arab botanical medicines has historical roots in ancient Arabic medicine. In the Middle Ages Arab herbalists, pharmacologists, chemists and physicians adapted the ancient medicinal practices of Mesopotamia, Greece, Rome, Persia and India. Medical innovations introduced by Arab physicians included: the discovery of the immune system, the introduction of microbiological science, and the separation of medicine from pharmacological science. This chapter presents a systematic review on traditional Arab botanical medicine including historical background, medical innovations introduced by Arab and Muslim physicians, and a state of the art description of traditional Arab herbal medicine.
Usefulness of auditory evoked potentials for studying the plasticity in cochlear implant users (2004)

"Usefulness of auditory evoked potentials for studying the plasticity in cochlear implant users." Cochlear Implants International, 5(sup1), pp. 15–16