gebhart/patrepeval huggingface dataset:
Efficient edge matching using improved hierarchical chamfer matching (2009)

Matching is a central problem in pattern recognition and computer vision, its applications includes object detection and tracking. HCMA (hierarchical chamfer matching) is a classical image matching algorithm, which utilizes the edge information to match the images robustly and the multi-resolution pyramid to accelerate the matching process. However, for images with cluttered background and high resolution, HCMA is relatively computationally expensive, which has impeded its success in practical applications, especially in real-time applications. In this paper, an improved hierarchical chamfer matching algorithm is proposed to reduce its computational cost without degrading its matching quality. According to the experimental results, the proposed improvements are able to save 75% ~ 95% of the computational time, without causing any false matching.
Coherence Ordering for Ring-based Chip Multiprocessors (2006)

Ring interconnects may be an attractive solution for future chip multiprocessors because they can enable faster links than buses and simpler switches than arbitrary switched interconnects. Moreover, a ring naturally orders requests sufficiently to enable directory-less coherence, but not in the total order that buses provide for snooping coherence. Existing cache coherence protocols for rings either establish a (total) ordering point (ORDERING-POINT) or use a greedy order (GREEDY-ORDER) with unbounded retries. In this work, we propose a new class of ring protocols, RING-ORDER, in which requests complete in ring position order to achieve two benefits. First, RING-ORDER improves performance relative to ORDERING-POINT by activating requests immediately instead of waiting for them to reach the ordering point. Second, it improves performance stability relative to GREEDY-ORDER by not using retries. Thus, the new RING-ORDER combines the best of ORDERING-POINT (good performance stability) with the best of GREEDY-ORDER (good average performance)
Characterization of a Metal-Dependent <scp>d</scp>-Psicose 3-Epimerase from a Novel Strain, Desmospora sp. 8437 (2013)

The rare sugar d-psicose is an ideal sucrose substitute for food products, due to having 70% of the relative sweetness but 0.3% of the energy of sucrose. It also shows important physiological functions. d-Tagatose 3-epimerase (DTEase) family enzymes can produce d-psicose from d-fructose. In this paper, a new member of the DTEase family of enzymes was characterized from Desmospora sp. 8437 (GenBank accession no. WP_009711885 ) and was named Desmospora sp. d-psicose 3-epimerase (DPEase) due to its highest substrate specificity toward d-psicose. Desmospora sp. DPEase was strictly metal-dependent and displayed maximum activity in the presence of Co(2+). The optimum pH and temperature were 7.5 and 60 °C, respectively. The enzyme was relatively thermostable below 50 °C, but easily lost initial activity when preincubated at 60 °C. The thermostability property was almost not affected by the addition of Co(2+). Desmospora sp. DPEase had relatively high catalysis efficiency for the substrates d-psicose and d-fructose, which were measured to be 327 and 116 mM(-1) min(-1), respectively. The equilibrium ratio between d-psicose and d-fructose of Desmospora sp. DPEase was 30:70. The enzyme could produce 142.5 g/L d-psicose from 500 g/L of d-fructose, suggesting that the enzyme is a potential d-psicose producer for industrial production.
Ultrathin silicon oxynitride film formation by plasma immersion nitrogen implantation (1999)

A method is proposed to prepare ultrathin silicon oxynitride films for gate dielectrics used in deep submicron metal–oxide–semiconductor field effect transistor device structures, namely plasma immersion N implantation into SiO2 films. Plasma immersion implantation pulse voltages in the range 200–1000 V, and fluences from 1016 to 1017 N cm−2 were implanted into thermally grown SiO2 films, with thicknesses between 3 and 6 nm. The areal densities of N and O in the resulting oxynitride films were determined by nuclear reaction analysis, before and after annealing in high-vacuum. N, O, and Si profiles in the films were determined with subnanometric depth resolution by medium energy ion scattering. The results indicate that plasma immersion ion implantation allows for shallow and controlled deposition of significant amounts of nitrogen (up to 3.8 nm of equivalent Si3N4 thickness). Implantation is accompanied by moderate damage at the oxynitride/Si interface which can be recovered by thermal annealing.
[Prevention of incontinence after radical prostatectomy]. (2006)

The incontinence after radical retropubic prostatectomy could be reduced by the method of preserving the membranous part of sphincter urethrae and preserving the neurovascular bundle lateral to the prostate in operation. It could also be avoided by evaginate the posterior wall of the bladder adequately and make an additional folding stitch to the bladder neck.
Elucidation of Lignin Structure by Quantitative 2D NMR (2011)

Quick quantitative HSQC (QQ-HSQC) was applied to quantitative evaluation of different inter-unit linkages in an array of milled softwood and hardwood and technical lignins by using the guaiacyl C2 and syringyl C2-C6 signals as internal standards. The results were found to be highly reproducible and comparable with earlier literature reports. The advantage of QQ-HSQC NMR analysis of lignin is contemporary detection and quantification of lignin inter-unit linkages with a direct, non-destructive method requiring short acquisition times.
Performability Modeling for RAID Storage Systems by Markov Regenerative Process (2015)

This paper presents a performability model for RAID storage systems using Markov regenerative process to compare different RAID architectures. While homogeneous Markov models are extensively used for reliability analysis of RAID storage systems, the memory-less property of the sojourn time assumed in such models is not satisfied in reality, especially in disk rebuild process whose progress is not interrupted even at an event of another disk failure. In this paper, we use Markov regenerative process which allows us to model the generally distributed rebuild times providing a needed extension of the traditional Markov models. The Markov regenerative process is then used to assess the performability of the storage system by assigning reward rates to each state based on the real storage benchmark results. Our numerical study characterizes the performability advantage of RAID6 architecture over RAID10 architecture in terms of sequential read access. Our findings include that the effect of exponential assumption for the rebuild times has practically negligible effect when we focus on data availability. However, the effect this approximation on performability prediction may not be negligible especially when the performance level drastically changes in degraded states. Our MRGP model provides more accurate prediction of performability in such cases.
Thyroid hormone attenuates and augments hepatic gene expression at a pretranslational level. (1981)

We have attempted to ascertain the proportion of the rat hepatic genome that is under the selective influence of thyroid hormones and to describe the response patterns of individual mRNA sequences in the transition between hypothyroidism and euthyroidism and between euthyroidism and hyperthyroidism. Poly(A)+RNA was extracted from livers of thyroidectomized, intact, euthyroid rats and of thyroidectomized rats rendered euthyroid and hyperthyroid with daily doses of triiodothyronine. The extracted RNA was translated in a reticulocyte lysate system in the presence of [35S]methionine, and the products were analyzed by two-dimensional gel electrophoresis. Triiodothyronine attenuates as well as augments the expression of certain genes at a pretranslational level. This could represent either a direct or an indirect action of the hormone. Triiodothyronine influences approximately 8% of the 231 mRNA sequences visualized, stimulating activity in 11 and inhibiting activity in 7 sequences. Translational activity of at least one mRNA sequence decreased in both thyroidectomized and hyperthyroid animals, compared to euthyroid levels. The relationship of mRNA response to receptor occupancy varied with examples of linear and amplified responses and responses that were maximal at less than full nuclear occupancy.
Antibiotics for Acne Vulgaris (1969)

Editorials1 October 1969Antibiotics for Acne VulgarisRUTH K. FREINKEL, M.D.RUTH K. FREINKEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-71-4-857 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAfter nearly 20 years of widespread use of broad-spectrum antibiotics in the therapy of acne vulgaris another report on the efficacy of tetracycline has appeared. Like most of the more than 20 previous studies with tetracycline or other broad-spectrum antibiotics this most recent trial by Williamson and Lane (1) reports favorable results. Such results parallel clinical usage as shown by Schmitt (2) in a survey of 1,150 dermatologists in 1963; 87% practicing dermatologists used antibiotics, usually broad spectrum, as the most frequent nontopical agent. In view of the apparent acceptance of this therapeutic modality, one wonders why clinical trials attempting...References1. LANE P and WILLIAMSON DM: Treatment of acne vulgaris with tetracycline hydrochloride: a double blind trial with 51 patients. Brit. Med. J. 2: 76, 1969. CrossrefMedlineGoogle Scholar2. SCHMITT CL: Current acne therapy. A compiled report. Arch. Derm. (Chicago) 87: 361, 1963. CrossrefMedlineGoogle Scholar3. SMITH MA and WATERWORTH PM: The bacteriology of acne vulgaris in relation to its treatment with antibiotics. Brit. J. Derm. 73: 152, 1961. CrossrefGoogle Scholar4. ROSENBERG EW: Bacteriology of acne. Ann. Rev. Med. 20: 201, 1969. CrossrefMedlineGoogle Scholar5. FREINKEL RK: Current concepts: pathogenesis of acne. New Eng. J. Med. 280: 1161, 1969. CrossrefMedlineGoogle Scholar6. GOLTZ RW and KJARTANSSON S: Oral tetracycline treatment on bacterial flora in acne vulgaris. Arch. Derm. (Chicago) 93: 92, 1966. CrossrefMedlineGoogle Scholar7. FREINKEL RK, STRAUSS JS, YIP SY, and POCHI PE: Effect of tetracycline on the composition of sebum in acne vulgaris. New Eng. J. Med. 273: 850, 1965. CrossrefMedlineGoogle Scholar8. STRAUSS JS and POCHI PE: Effect of orally administered antibacterial agents on the titratable acidity of human sebum. J. Invest. Derm. 47: 577, 1966. CrossrefMedlineGoogle Scholar9. RASHLEIGH PL, RIFE E, and GOLTZ RW: Tetracycline levels in skin surface film after oral administration of tetracycline to normal adults and to patients with acne vulgaris. J. Invest. Derm. 49: 611, 1967. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RUTH K. FREINKEL, M.D.Affiliations: Department of Dermatology Northwestern University Medical School 303 E. Chicago Ave. Chicago, Ill. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byClinical Dermatology 1 October 1969Volume 71, Issue 4 Page: 857-858 Keywords Acne Antibiotics Clinical trials Tetracyclines ePublished: 1 December 2008 Issue Published: 1 October 1969 PDF downloadLoading ...
Multiwavelength and tunable regenerative laser resonator with passive self-pulsating action (2008)

We experimentally demonstrate the operation of a self-pulsating laser that is dual-wavelength and continuously wavelength-tunable. This passive laser is extremely simple to implement and has properties that theoretically enables signal buffering.
Role of exosomes in immune regulation (2006)

Exosomes are small vesicles originating from late endosomes, 30-100 nm in diameter with typical cup-shape morphology. They are reported to bear high levels of a narrow spectrum of molecules involved in immune response and signal transduction. Apart from removing obsolete membrane proteins, some surprising biological functions of exosomes were unveiled recently and their applications in immunotherapy of tumors are currently intensively investigated. Dendritic cell- (DC) and tumor-derived exosomes have considerable anti-tumor effects in experimental studies and several clinical trials. Despite their potential applications in eliciting a "positive" immune response, exosomes might induce some "unwanted" immune responses, such as immune tolerance and immune evasion. Therefore further investigations about the physiological functions of exosomes and the optimal way of exosome application in tumor immunotherapy are necessary. This review presents recent developments in the field of exosome research and focuses on its applications to tumor immunotherapy.
Phosphorylation of kinase insert domain receptor by cyclin-dependent kinase 5 at serine 229 is associated with invasive behavior and poor prognosis in prolactin pituitary adenomas (2016)

Pituitary adenomas constitute 15-20% of intracranial neoplasms. Previously we reported that cyclin-dependent kinase 5 (CDK5) is upregulated in pituitary tumors associated with activating protein p35, and plays an essential role in pituitary adenomas progression. Here we explored the mechanisms of CDK5 signaling in prolactin pituitary adenomas. Our data indicate that p35 expression and CDK5 activity are both significantly increased in human invasive prolactin pituitary adenomas as compared to noninvasive forms of pituitary adenomas. Inhibition of CDK5 activity suppressed cell migration and invasive ability in GH3 rat pituitary cells. We identified that CDK5 phosphorylates serine 229 residue (Ser-229) of kinase insert domain receptor (KDR), also known as VEGFR-2, in prolactin pituitary adenomas. Phosphorylation of Ser-229 is required for proper KDR surface localization. Phosphorylated Ser-229 in KDR (pSer-229) levels are significantly higher in noninvasive and invasive prolactin pituitary adenomas compared to normal pituitary tissues. In addition, our data indicated that higher KDR pSer-229 correlates with worse prognosis in patients with prolactin pituitary adenomas. In summary, our results illustrated that CDK5-mediated KDR phosphorylation controls prolactin pituitary adenoma progression and KDR pSer-229 serves as a potential prognostic biomarker for both noninvasive and invasive pituitary adenomas.
The impact of the human rights act in the community (2014)

I begin by acknowledging the traditional owners of the land on which we meet. In the context of our discussion today about Human Rights, I take the opportunity to recognise the immeasurable Human Rights abuses that Aboriginal and Torres Strait Islander people have experienced at the hands of non-indigenous persons since white settlement. Today, Aboriginal and Torres Strait Islander members of our community remain at greatest risk of not receiving the support they need to remedy legal issues. Despite this, generations of Aboriginal and Torres Strait Islander peoples in this region have kept their families strong in the face of extraordinary hardship. I take this opportunity to acknowledge your strength, and to pay you my respects.
Taurine and Hypotaurine Content of Human Leukocytes (1990)

Taurine (T) was reported to be at high concentrations in human leukocytes. It was proposed that T is a scavenger for chlorinated oxidants produced by the myeloperoxidase system of monocytes and neutrophils. Hypotaurine (HT) would be a more effective scavenger, and HT could also detoxify products of bromide or iodide oxidation produced by the eosinophil peroxidase system. Methods previously used to measure T in leukocytes might oxidize HT to T or fail to separate T and HT. Therefore, we examined T and HT content, uptake, and biosynthesis in isolated blood cells and cultured tumor cells derived from hematopoietic/lymphoid cells. Platelets and all leukocytes including monocytes, lymphocytes, neutrophils, and eosinophils had high T levels (10-20 mM), and all except eosinophils had substantial HT levels (0.3-1 mM). Intracellular levels were 500-times higher than in plasma. Erythrocytes were the only blood cells with low levels of both T and HT. Tumor cells from lymphoid (CCRF-CEM) and myeloid (HL-60, K-562, RWLeu4, HEL) lineages took up and concentrated T and HT from the bovine calf serum in the culture medium, and intracellular levels were similar to those in leukocytes. When cells were cultured in HT-supplemented media, HT almost completely replaced T, and HT was not converted to T. Levels of T were not raised by culturing cells with possible precursors, but HT levels were raised when cysteine sulfinic acid was present. Washed tumor cells took up T and HT by way of a beta-amino acid transport system, but uptake by leukocytes was very low. Therefore, leukocytes may acquire T and HT by active uptake rather than biosynthesis, and uptake may be completed during differentiation in the bone marrow. Though HT is low relative to T, HT levels may be sufficient to protect leukocytes from toxic oxidants.
APELIN IN EPIRETINAL FIBROVASCULAR MEMBRANES OF PATIENTS WITH RETINOPATHY OF PREMATURITY AND THE CHANGES AFTER INTRAVITREAL BEVACIZUMAB (2013)

The apelin/APJ system may be involved in the development of retinal neovascularization of ROP. The present results showed that the effect of apelin was related to HIF-1a but independent with VEGF.
The Maternal Effect Genes UTX and JMJD3 Play Contrasting Roles in Mus musculus Preimplantation Embryo Development (2016)

During the process of embryonic development in mammals, epigenetic modifications must be erased and reconstructed. In particular, the trimethylation of histone 3 lysine 27 (H3K27me3) is associated with gene-specific transcriptional repression and contributes to the maintenance of the pluripotent embryos. In this study, we determined that the global levels of the H3K27me3 marker were elevated in MII oocyte chromatin and decrease to minimal levels at the 8-cell and morula stages. When the blastocyst hatched, H3K27me3 was re-established in the inner cell mass. We also determined that H3K27me3-specific demethylases, UTX and JMJD3, were observed at high transcript and protein levels in mouse preimplantation embryos. In the activated oocytes, when the H3K27me3 disappeared at the 8-cell stage, the UTX (but not JMJD3) protein levels were undetectable. Using RNA interference, we suppressed UTX and JMJD3 gene expression in the embryos and determined that the functions of UTX and JMJD3 were complementary. When JMJD3 levels were decreased by RNA interference, the embryo development rate and quality were improved, but the knockdown of UTX produced the opposite results. Understanding the epigenetic mechanisms controlling preimplantation development is critical to comprehending the basis of embryonic development and to devise methods and approaches to treat infertility.
Extended lapped transforms with linear phase basis functions and perfect reconstruction (2005)

In this paper we introduce the theory and design of a new class of Extended lapped transform with basis functions having linear phase property and perfect reconstruction. Lapped Transforms are powerful tools for signal, image and video processing applications. The Extended Lapped transform reported previously in the literature is a modulated lapped transform. Even though they provide efficient implementation the basis functions do not have the linear phase property. This property is crucial in image coding applications at low bit rates. Linear phase property not only eliminates phase distortion but also permit use of simple symmetric extension methods to accurately handle boundaries of the finite length signals. Furthermore linear phase property leads to more efficient implementation. The formulation is based on type II Discrete Cosine Transform (DCT II). Hence it has fast and efficient structure. The necessary and sufficient conditions for Perfect Reconstruction and linear phase are derived.
Associative semantic ranking of satellite images using PathFinder Network Scaling ensemble methods (2012)

This article proposes a methodology to reduce overfitting when ranking high-resolution satellite images by domain semantics. Our approach uses PathFinder Network Scaling ensemble methods. We generate cross-fold co-occurrence matrices for relevance of feature subspaces to each semantic. Each matrix is then reduced using the PathFinder network scaling algorithm. Irrelevant nodes are removed using node strength metrics resulting in an optimized model for ranking by semantic that generalizes better to new images. The experiments show that, when using this approach, the quality of ranking by semantic can be significantly improved. Results show that Mean Average Precision (MAP) of ranking over cross-fold experiments increased by a 13.2% while standard deviation of MAP was reduced by 16.8% relatively to experiments without PathFinder network scaling.
PROMISING EARLY OUTCOMES WITH A NOVEL, COMPLETE STEROID AVOIDANCE IMMUNOSUPPRESSION PROTOCOL IN PEDIATRIC RENAL TRANSPLANTATION1 (2001)

Complete steroid-free immunosuppression is efficacious and safe in this selected group of children with no early clinical acute rejection episodes. This protocol avoids the morbid side effects of steroids without increasing infection, and may play a future critical role in avoiding noncompliance, although optimizing renal function and growth.
Low-temperature DC characteristics of pseudomorphic Ga/sub 0.18/In/sub 0.82/P/InP/Ga/sub 0.47/In/sub 0.53/As HEMT (1990)

A high-gap strained GaInP material chosen to increase Schottky barrier height on InP is discussed. This material has been used for the first time in high electron mobility transistor (HEMT) fabrication on InP. For these devices the best g/sub m/ of a 1.3- mu m gate HEMT is 300 mS/mm. Transistors of 3- mu m gate length are studied at low temperature (100 to 293 K). Their DC electrical characteristics improve upon cooling. The best improvement is measured at the lowest temperature (+54% for g/sub m/ at 105 K). The structure is stable and does not present any g/sub m/ or I/sub ds/ collapse at low temperature, unlike AlGaAs/GaAs heterostructures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Antidepressant-associated mania: a controlled comparison with spontaneous mania (1994)

Antidepressant-associated mania appears to be a milder and more time-limited syndrome than spontaneous mania and may represent a distinct clinical entity. MAOIs and bupropion may be associated with milder manic states than either tricyclic drugs or fluoxetine.