gebhart/patrepeval huggingface dataset:
MRC diversity with an output threshold (2004)

Diversity combining technique greatly improves the performance of wireless communication systems in fading environment. However, it also increases the power consumption of the receiver. In this paper, we investigate a variant of the classical maximum ratio combining (MRC) scheme that minimizes the processing power at the receiver while still providing considerable performance improvement. In particular, we carry out a thorough performance versus power consumption tradeoff analysis of the output-thresholded MRC scheme. Numerical examples show that the output thresholded combining scheme leads to considerable less average power consumption than conventional MRC scheme while providing nearly the same performance.
Selection of a Bifidobacterium strain to complement resistant starch in a synbiotic yoghurt (2001)

In vitro screening procedures can be used to integrate complementary probiotic and prebiotic ingredients for new synbiotic functional food products.
Molecular characterization of adenocarcinoma and squamous carcinoma of the uterine cervix using microarray analysis of gene expression (2006)

In an attempt to understand the molecular mechanisms for the different clinical features between adenocarcinoma/adenosquamous carcinoma (AC/ASC) and squamous carcinoma (SC) of the uterine cervix, we analyzed gene expression profiles of different histological subtypes of cervical cancer. Cancer specimens and the surrounding normal tissue counterparts were separately collected from cervical cancer patients undergoing type III radical hysterectomy. Paired total RNA (cancer and normal tissues) was isolated and analyzed with cDNA microarrays containing duplicate spots of 7 334 sequence-verified human cDNA clones. Selected differentially expressed genes specific for AC or SC were further verified using real-time quantitative polymerase chain reaction (RTQ-PCR) and immunohistochemistry. Genes, including CEACAM5, TACSTD1, S100P and MSLN were upregulated in AC. Contrarily, genes involved in epidermal differentiation complex such as S100A9 and ANXA8 were upregulated in SC. Cross-validation of the results using an independent but comparable group of patients with known long-term outcomes (n = 63, median follow-up 70.3 months; range, 4-208 months) showed that the correlation between the selected 6 differentially expressed genes and histology was highly significant. CEACAM5 (p < 0.0001) and TACSTD1 (p = 0.009) were significant prognostic factors by multivariate Cox proportional hazards regression analysis. The combination of cDNA microarray, RTQ-PCR and immunohistochemical results of this study showed that it is possible to define different gene profiles for AC and SC. Moreover, TACSTD1 expression may be a novel poor prognostic factor.
Artifacts of CD Burning in the Microsoft Windows Master File Table (2011)

When theft of a physical item occurs it is detectable by the fact that the object is missing, however, when the theft of a digital item occurs it can go unnoticed as exact replicas can be created. The original file is left intact but valuable information has been absconded. One of the challenges facing digital forensic examiners is detecting when files have been copied off of a computer system in some fashion. While certain methods do leave residual evidence behind, CD Burning has long been held as a copying method that cannot be identified. Through testing of the burning process and close examination of the New Technology File System (NTFS), artifacts from the master file table in the various versions of Microsoft Windows, markers have been found that are associated with copying or "burning" files to CD or DVD. Potential evidence that was once overlooked may now be detectable.
A novel timestamp ordering approach for co-existing traditional and cooperative transaction processing (1998)

In order to support both traditional short transaction and long cooperative transactions, we propose a novel timestamp ordering approach. With this timestamp ordering method, short transactions can be processed in the traditional way, as if there are no cooperative transactions, therefore not be blocked by long transactions; cooperative transactions will not be aborted when there is a conflict with short transactions, rather it will incorporate the recent updates into its own processing; and the serializabilities, among short transactions, and between a cooperative transaction (group) and other short transactions, are all preserved.
Crystallization kinetics and viscosity of Cu47Ti33Zr11Ni8X1 (X=Si, Sn) metallic glasses (2008)

Crystallization kinetics of Cu47Ti34Zr11Ni8 and Cu47Ti33Zr11Ni8X1 (X = Si, Sn) metallic glasses was investigated by the Johnson-Mehl-Avrami method. The Avrami exponent of 2.5
An approximate deconvolution model for large-eddy simulation with application to incompressible wall-bounded flows (2001)

The approximate deconvolution model (ADM) for the large-eddy simulation of incompressible flows is detailed and applied to turbulent channel flow. With this approach an approximation of the unfiltered solution is obtained by repeated filtering. Given a good approximation of the unfiltered solution, the nonlinear terms of the filtered Navier–Stokes equations can be computed directly. The effect of nonrepresented scales is modeled by a relaxation regularization involving a secondary filter operation. Large-eddy simulations are performed for incompressible channel flow at Reynolds numbers based on the friction velocity and the channel half-width of Reτ=180 and Reτ=590. Both simulations compare well with direct numerical simulation (DNS) data and show a significant improvement over results obtained with classical subgrid scale models such as the standard or the dynamic Smagorinsky model. The computational cost of ADM is lower than that of dynamic models or the velocity estimation model.
Regulation of Heat Shock Protein 90 ATPase Activity by Sequences in the Carboxyl Terminus (2002)

Hsp90, in addition to being an abundant and pivotal cytoplasmic chaperone protein, has been shown to be a weak ATPase. In an effort to characterize the ATPase activity of hsp90, we have observed marked differences in activities among various species of hsp90. Chicken or human hsp90 hydrolyzed ATP with a k(cat) of 0.02 min(-1) and a K(m) greater than 300 microm. In contrast, yeast hsp90 and TRAP1, an hsp90 homologue found in mitochondria, were 10-100-fold more active as ATPases. Sedimentation studies confirmed that all are dimeric proteins. Chicken hsp90 mutants were then analyzed to identify regions within the protein that influence ATPase activity. A truncation mutant of chicken hsp90, N1-573, was found to be monomeric, and yet the catalytic efficiency (k(cat)/K(m)) was greater than 100 times that of the full-length protein (k(cat) of 0.24 min(-1) and K(m) of 60 microm). In contrast, an internal deletion mutant, Delta661-677, was also monomeric but failed to hydrolyze ATP. Finally, deletion of the last 30 amino acids resulted in a dimeric protein with an ATPase activity very similar to full-length hsp90. These data indicate that sequences within the last one-fourth of hsp90 regulate ATP hydrolysis.
Filter subsystems for wireless communications (1997)

Thin-film oxide superconductor materials and advanced processing techniques have been used to fabricate high-performance filters for cellular communications base stations. Quasi-elliptic bandpass and band reject filters were designed and realized using microstrips to approximate lumped elements. These quasi-lumped resonators have achieved unloaded Q's of more than 40,000. Precise system control allows for high operating temperature (77 K), using either Yttrium or Thallium high T/sub c/ compounds, compensating for temperature dependence. Such filters have been successfully integrated into a permanently evacuated dewar and cooled by a miniature Stirling cycle cooler. The cooler and dewar were integrated with control electronics which run off standard cellular base station +27 V power sources. The system consumes less than 100 W in operation, making it one of the most efficient HTSC subsystems demonstrated to date.
Cardiovascular Safety of Degarelix: Results From a 12-Month, Comparative, Randomized, Open Label, Parallel Group Phase III Trial in Patients With Prostate Cancer (2010)

In men with prostate cancer degarelix and leuprolide have similar cardiovascular safety profiles. These observations suggest that the cardiovascular events associated with both agents result from hypogonadism rather than a direct drug effect.
Very Low Reset Current for an RRAM Device Achieved in the Oxygen-Vacancy-Controlled Regime (2011)

We propose the bipolar-mode operation of resistive random access memory devices in a purely oxygen-vacancy (V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> )-controlled regime, which is achieved by very low compliance capping for forming/set transitions. This regime enables us to achieve a very low reset current of 10-100 nA, in which the governing mechanism for switching only involves the reversible drift of oxygen ions to and from oxygen soluble gate electrodes. The physical analysis of a gate stack in this V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> regime confirms the absence of metallic nanofilaments. These findings pave the way for the realization of ultralow switching power RRAM devices.
Arbitrary-ratio image resizing using fast DCT of composite length for DCT-based transcoder (2006)

We propose a fast arbitrary-ratio image resizing method for transcoding of the compressed images. The downsizing process in the discrete cosine transform (DCT) domain can be implemented by truncating high-frequency coefficients, whereas the upsizing process is implemented in the DCT domain by padding zero coefficients to the high-frequency part. The proposed method combines a fast inverse and forward DCT of composite length for arbitrary-ratio upsizing or downsizing. According to the resizing ratio, truncating the high-frequency coefficients and padding zeros are appropriately considered by combining the inverse DCT and forward DCT. The proposed method shows a good peak signal-to-noise ratio and less computational complexity compared with the spatial-domain and previous DCT-domain image resizing methods.
Protein inhibitors of serine proteinases. (1999)

Serine proteinases and their natural protein inhibitors belong to the most intensively studied models of protein-protein recognition. Protein inhibitors do not form a single group but can be divided into about 20 different families. Global structures of proteins representing different inhibitor families are completely different and comprise alpha-helical proteins, beta-sheet proteins, alpha/beta-proteins and different folds of small disulfide-rich proteins. Three different types of inhibitors can be distinguished: canonical (standard mechanism) inhibitors, non-canonical inhibitors, and serpins. The canonical inhibitor binds to the enzyme through the exposed and convex binding loop, which is complementary to the active site of the enzyme. The mechanism of inhibition in this group is consistently very similar and resembles that of an ideal substrate. Non-canonical inhibitors, originating from blood sucking organisms, specifically block enzymes of the blood clotting cascade. The interaction is mediated through inhibitor N-terminus which binds to the proteinase forming a parallel beta-sheet. There are also extensive secondary interactions which provide an additional buried area and contribute significantly to the strength and specificity of recognition. Serpins are major proteinase inhibitors occurring in plasma. Similarly to canonical inhibitors, serpins interact with their target proteinases in a substrate-like manner. However, in the case of serpins, cleavage of a single peptide bond in a flexible and exposed binding loop leads to dramatic structural changes.
Aneka Cloud Application Platform and Its Integration with Windows Azure (2011)

Aneka is an Application Platform-as-a-Service (Aneka PaaS) for Cloud Computing.It acts as a framework for building customized applications and deploying them on either public or private Clouds.One of the key features of Aneka is its support for provisioning resources on different public Cloud providers such as Amazon EC2, Windows Azure and GoGrid.In this chapter, we will present Aneka platform and its integration with one of the public Cloud infrastructures, Windows Azure, which enables the usage of Windows Azure Compute Service as a resource provider of Aneka PaaS.The integration of the two platforms will allow users to leverage the power of Windows Azure Platform for Aneka Cloud Computing, employing a large number of compute instances to run their applications in parallel.Furthermore, customers of the Windows Azure platform can benefit from the integration with Aneka PaaS by embracing the advanced features of Aneka in terms of multiple programming models, scheduling and management services, application execution services, accounting and pricing services and dynamic provisioning services.Finally, in addition to the Windows Azure Platform we will illustrate in this chapter the integration of Aneka PaaS with other public Cloud platforms such as Amazon EC2 and GoGrid, and virtual machine management platforms such as Xen Server.The new support of provisioning resources on Windows Azure once again proves the adaptability, extensibility and flexibility of Aneka.
Changes in Tasting Constituents (Tannin, Free Sugar, Total Nitrogen ) of Green Tea by Leaching Condition (1989)

Optimum leaching conditions of Korean green tea were determined by examining the relationship between sensory evaluation and tasting constituents of green tea infusion at various leaching conditions. Total nitrogen, total reducing sugar and tannin contents of green tea were , and , respectively. They increased with the increased of leaching temperature and time. The sensory score was significantly correlated with the tannin contents of green tea in fusion in the range of .(r=-0.9061). Optimum leaching conditions of green tea were min at , 0.5 min at in high grade parched green tea, min at and min at in medium one.
A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group (1997)

EGb was safe and appears capable of stabilizing and, in a substantial number of cases, improving the cognitive performance and the social functioning of demented patients for 6 months to 1 year. Although modest, the changes induced by EGb were objectively measured by the ADAS-Cog and were of sufficient magnitude to be recognized by the caregivers in the GERRI.
ChemInform Abstract: Efficient, Catalytic, Aerobic Oxidation of Alcohols with Octahedral Molecular Sieves. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The LHC beam pipe waveguide mode reflectometer (2007)

The waveguide-mode reflectometer for obstacle detection in the LHC beam pipe has been intensively used for more than 18 months. The "Assembly" version is based on the synthetic pulse method using a modern vector network analyzer. It has mode selective excitation couplers for the first TE and TM mode and uses a specially developed waveguide mode dispersion compensation algorithm with external software. In addition there is a similar "In Situ" version of the reflectometer which uses permanently installed microwave couplers at the end of each of the nearly 3 km long LHC arcs. During installation a considerable number of unexpected objects have been found in the beam pipes and subsequently removed. Operational statistics and lessons learned are presented and the overall performance is discussed.
Allosteric Modulation of the Dopamine D <sub>2</sub> Receptor by Pro-Leu-Gly-NH <sub>2</sub> Peptidomimetics Constrained in Either a Polyproline II Helix or a Type II β-Turn Conformation (2009)

Type II beta-turn mimics and polyproline II helix mimics based upon diastereoisomeric 5.6.5 spiro bicyclic scaffolds have provided two pairs of Pro-Leu-Gly-NH(2) (PLG) peptidomimetics with contrasting dopamine receptor modulating activities. Compounds 1a and 3a were found to be positive allosteric modulators of the dopamine receptor, while the corresponding diastereoisomeric compounds 1b and 3b provided the first PLG peptidomimetics with the ability to decrease the binding of agonists to the dopamine receptor. The positive allosteric modulating activity of 3a supported the hypothesis that a polyproline II helix conformation is the bioactive conformation for the PLG analogue Pro-Pro-Pro-NH(2). The results also show that a change in the bridgehead chirality of the 5.6.5 scaffold brings about opposite effects in terms of the modulation of the dopamine receptor.
Polarized light scattering from metal surfaces (1987)

The stretching and bending of polished and industrial-grade metallurgical surfaces changes the appearance of the specimen’s surface. The changes in surface structure can be detected in the polarized light scattered from the surface cracks and other defects, which act as scattering centers. In order to interpret light scattering signals from complex surfaces, we first examine the nature of light scattered from a perfect mirror surface, a degraded mirror, a line on a mirror, a randomly sanded surface, and, finally, the industrial grade metal surfaces damaged by stretching and bending.
Autophagy in a Mouse Model of Distal Myopathy with Rimmed Vacuoles or Hereditary Inclusion Body Myopathy (2007)

In the article Autophagy in a Mouse Model of Distal Myopathy with Rimmed Vacuoles or Hereditary Inclusion Body Myopathy by May Christine V. Malicdan, Satoru Noguchi and Ichizo Nishino (Autophagy 2007; 3:396-8) the authors describe a transgenic mouse that displays the human distal myopathy with rimmed vacuoles (DMRV) phenotype. In this report, the mutation used to generate the mutation was incorrectly written as “V572L” when it should have been “D176V”. Accordingly, the transgenic mice should be named “Gne-/- hGNED176V-Tg”. All of the other data have been verified by repeated experiments. Furthermore, the finding that the mouse phenotype resembles human DMRV, including the presence of autophagy, remains valid. We apologize for any inconvenience this may have caused.
Adenovirus‐mediated gene transfer in canine eyes: a preclinical study for gene therapy of human uveal melanoma (2001)

Background Melanomas of the uveal tract are the most common intraocular malignancies in adults, with an incidence of six cases per million adults per year. Enucleation, which may enhance the dissemination of tumour cells into the systemic circulation, is still required for eyes with large tumours. Gene therapy is proposed as a new therapeutic approach for uveal melanoma management. Methods The potential of adenovirus-mediated gene transfer to normal eyes of two laboratory Beagles and in an iris tumour of a Great Dane were evaluated. Replication-defective adenoviral vectors (Adβgal) were used to assess the feasibility, efficiency and safety of direct adenoviral delivery to the anterior chamber of normal eyes and to an iris tumour. The expression of angiostatin into the aqueous humour following an adenoviral-mediated delivery of human angiostatin (AdK3) was also investigated. Results The ciliary body was the area preferentially transduced after adenoviral injection into the anterior chamber. It was also demonstrated that a direct intratumoral injection of a recombinant adenovirus efficiently transduces a canine uveal melanoma. Western blot analysis performed on the aqueous humour revealed that the expression of the angiostatin recombinant protein in the aqueous humour correlated with the dose of AdK3 administered. Lymphocyte infiltrates at the site of AdK3 injection indicated induction of a strong cellular immune response, and humoral immune responses developed in all three dogs. Conclusions The present study involving adenovirus-mediated gene transfer to dog eyes provides an essential basis for gene therapy treatment of uveal melanoma-bearing patients. Copyright © 2001 John Wiley & Sons, Ltd.
Le transistor-thyristor métal-oxyde-semiconducteur (T2 MOS) (1985)

On présente un nouveau composant planar contrôlé par un effet « Métal-Oxyde-Semiconducteur », dont les caractéristiques électriques peuvent être : i) de type transistor MOS, ii) de type thyristor MOS ou bien iii) être la combinaison des deux précédentes. On l'appelle le « transistor-thyristor MOS » ou T2 MOS. Un exemple de réalisation technologique est décrit et les caractéristiques électriques sont présentées. Des variantes de configurations par rapport à la géométrie de ce prototype sont suggérées. Des utilisations possibles de ces structures sont évoquées.
Foundations of intelligent tutoring systems : an introduction (1988)

Excerpts available on Google Books (see link below). For more information, go to publisher's website : http://www.taylorandfrancis.com/books/details/9780805800548/
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer (2013)

Colorectal cancer (CRC) is one of the leading causes of cancer related deaths and the search for prognostic biomarkers that might improve treatment decisions is warranted. MicroRNAs (miRNAs) are short non-coding RNA molecules involved in regulating gene expression and have been proposed as possible biomarkers in CRC. In order to characterize the miRNA transcriptome, a large cohort including 88 CRC tumors with long-term follow-up was deep sequenced. 523 mature miRNAs were expressed in our cohort, and they exhibited largely uniform expression patterns across tumor samples. Few associations were found between clinical parameters and miRNA expression, among them, low expression of miR-592 and high expression of miR-10b-5p and miR-615-3p were associated with tumors located in the right colon relative to the left colon and rectum. High expression of miR-615-3p was also associated with poorly differentiated tumors. No prognostic biomarker candidates for overall and metastasis-free survival were identified by applying the LASSO method in a Cox proportional hazards model or univariate Cox. Examination of the five most abundantly expressed miRNAs in the cohort (miR-10a-5p, miR-21-5p, miR-22-3p, miR-143-3p and miR-192-5p) revealed that their collective expression represented 54% of the detected miRNA sequences. Pathway analysis of the target genes regulated by the five most highly expressed miRNAs uncovered a significant number of genes involved in the CRC pathway, including APC, TGFβ and PI3K, thus suggesting that these miRNAs are relevant in CRC.
Clinical Value of Serum CA15-3 in Patients with Breast Cancer (2002)

Objective To evaluate the clinical value of CA15 3 in patients with breast cancer.Method Serum levers of CA15 3 and CEA were determined in 422 patients with benign and malignant breast diseases.Results The positive rates of CA15 3(30U/ml) and CEA(15ng/ml) were lower in patients with benign and without metastatic breast cancer.The sensitivity in patients with metastatic and reoccurred breast cancer was 75% in CA15 3,33% in CEA.CA15 3 increased before the clinical diagnosis.Conclusions The sensitivities of serum CA15 3 and CEA to breast cancer are not apparent.The metastasis and reoccurrence of breast cancer should be considered while serum CA15 3 and CEA increase at the same time or are persistent positive.The sensitivity of CA15 3 is higher than other indexes.