gebhart/patrepeval huggingface dataset:
Noninvasive Cardiac Output: Simultaneous Comparison of Two Different Methods with Thermodilution (1990)

The authors attempted to simultaneously measure cardiac output by thermodilution (COtd), thoracic bioimpedance (CObi), and suprasternal Doppler ultrasound (COdopp) in 68 patients. Subgroups separately compared included patients whose lungs were mechanically ventilated, patients undergoing cardiac surgery, aortic surgery, patients with dysrhythmias, and patients with sepsis. The authors also studied the value of the ventricular ejection time (VET) in evaluating the agreement of CObi and COdopp with COtd. Simultaneous CObi and COtd were available in a total of 56 patients (416 data sets) with an overall correlation coefficient r = 0.61, regression slope (m) of 0.52, intercept (y) of 2.46, and mean (CObi-COtd) difference (bias) of -0.67 +/- 1.72 (SD) l/min. Simultaneous COdopp and COtd were available in 59 patients (446 data sets) with an overall r = 0.51, m of 0.53, y of 2.05, and bias of -0.79 +/- 1.95 l/min. CObi agreed most closely with COtd in patients whose lungs were mechanically ventilated, who had not undergone cardiac or aortic surgery, and with VET difference less than 40 ms (16 patients, 99 data sets; r = 0.74; m = 0.97; y = 0.15; bias = -0.02 +/- 1.53 l/min). COdopp agreed most closely with COtd in patients whose lungs were mechanically ventilated, who had not undergone cardiac or aortic surgery, and in sinus rhythm with VET difference less than 40 ms (10 patients, 45 data sets; r = 0.82; m = 0.98; y = -0.07; bias = -0.82 +/-1.03 l/min). VET by radial artery can help evaluate the reliability of CObi and COdopp.
Peptide and small molecule inhibitors of the Keap1–Nrf2 protein–protein interaction (2015)

The transcription factor nuclear factor erythroid-2-related factor 2 (Nrf2) up-regulates the expression of a range of cytoprotective enzymes with antioxidant response elements in their promoter regions and thus can protect cells against oxidative damage. Increasing Nrf2 activity has been proposed as a therapeutic intervention in a range of chronic neurodegenerative conditions and cancer chemoprevention. One of the main mechanisms by which Nrf2 is negatively regulated involves an interaction with the ubiquitination facilitator protein, Kelch-like ECH-associated protein 1 (Keap1) that facilitates degradation of Nrf2. Inhibition of this process underlies the mode of action of a broad group of compounds that increase Nrf2 activity. A number of natural products, including the isothiocyanate sulforaphane, up-regulate Nrf2 by interacting with Keap1 in a covalent manner to stall its activity. Recently, a number of peptide and small molecule inhibitors of the protein-protein interaction (PPI) between Keap1 and Nrf2 have been described. These classes of compound have contrasting modes of action at the molecular level and there is emerging evidence that their biological activities have similarities and differences. This review describes the various classes of PPI inhibitor that have been described in the literature and the biological evaluations that have been performed.
Interferon-γ and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation (2001)

Proinflammatory cytokines including interferon-gamma (IFNgamma), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNFalpha) are implicated in the pathogenesis of acute graft-versus-host disease (aGVHD). Cytokine gene polymorphism is associated with functional differences in cytokine regulation and altered clinical performance in a variety of diseases. Polymorphism in the IFNgammaIntron1 microsatellite (CA)n repeat has been linked with in vitro IFNgamma production and renal transplant rejection. The IL-6(-174)(G/C) single nucleotide polymorphism has been linked to in vitro and in vivo IL-6 production, juvenile chronic arthritis, and renal transplant rejection. This study examined the potential association of GVHD with IFNgamma and IL-6 polymorphisms in 80 sibling bone marrow transplant (BMT) donor/recipient pairs. Patients homozygous for the IFNgammaIntron1 allele 3 had more severe (grade III-IV) aGVHD. Patients possessing the IL-6(-174)G allele had a trend toward higher grades of aGVHD, and those homozygous for the IL-6(-174)G allele were more likely to develop chronic GVHD (cGVHD). The associations of previously identified aGVHD severity-associated cytokine gene polymorphisms (TNFd and IL-10(-1064)) with severe aGVHD were reconfirmed. Logistic regression analysis confirmed the association of severe aGVHD with recipient genotype at IFNgammaIntron1 (odds ratio [OR] 3.92; P =.02), IL-10(-1064) (OR 4.61; P =.026) and TNFd (OR 3.29; P =.039), and that of cGVHD with recipient IL-6(-174) genotype (OR 4.25; P =.007), in addition to age, gender mismatch, and underlying disease. Assessment of cytokine genotype may potentially allow more accurate prediction of GVHD and appropriate adjustment of GVHD prophylaxis, as well as indicating novel areas for future studies of GVHD pathogenesis.
Preparation of Gelled Substrates (1998)

Gelled substrates can be used for a variety of in vitro and in vivo experiments. A type I collagen gelled substrate will promote cell growth and differentiation. Gelled Matrigel substrate promotes the survival of explanted cells and tissues and the differentiation of a variety of epithelial and endothelial cell types in vitro and to assess angiogenesis and increase tumor growth in vivo. Preparation of the matrices and their use are described in this unit.
Reagan ha perdido la razón por Nicaragua (1986)

No hay resúmenes disponibles. ECA Estudios Centreamericanos, Vol. 41, No. 449, 1986: 241-244.
Automated Detection of Language Issues Affecting Accuracy, Ambiguity and Verifiability in Software Requirements Written in Natural Language (2010)

Most embedded systems for the avionics industry are considered safety critical systems; as a result, strict software development standards exist to ensure critical software is built with the highest quality possible. One of such standards, DO-178B, establishes a number of properties that software requirements must satisfy including: accuracy, non-ambiguity and verifiability. From a language perspective, it is possible to automate the analysis of software requirements to determine whether or not they satisfy some quality properties. This work suggests a bounded definition for three properties (accuracy, non-ambiguity and verifiability) considering the main characteristics that software requirements must exhibit to satisfy those objectives. A software prototype that combines natural language processing (NLP) techniques and specialized dictionaries was built to examine software requirements written in English with the goal of identifying whether or not they satisfy the desired properties. Preliminary results are presented showing how the tool effectively identifies critical issues that are normally ignored by human reviewers. 1
Evidence for multiple polytypes of semiconducting boron carbide (C<sub>2</sub>B<sub>10</sub>) from electronic structure (2005)

Boron carbides fabricated via plasma enhanced chemical vapour deposition from different isomeric source compounds with the same C2B10H12 closo-icosahedral structure result in materials with very different direct (optical) band gaps. This provides compelling evidence for the existence of multiple polytypes of C2B10 boron carbide and is consistent with electron diffraction results.
Kinase RIP3 Is Dispensable for Normal NF-κBs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4 (2004)

RIP3 is a member of the RIP kinase family. It is expressed in the embryo and in multiple adult tissues, including most hemopoietic cell lineages. Several studies have implicated RIP3 in the regulation of apoptosis and NF-kappa B signaling, but whether RIP3 promotes or attenuates activation of the NF-kappa B family of transcription factors has been controversial. We have generated RIP3-deficient mice by gene targeting and find RIP3 to be dispensable for normal mouse development. RIP3-deficient cells showed normal sensitivity to a variety of apoptotic stimuli and were indistinguishable from wild-type cells in their ability to activate NF-kappa B signaling in response to the following: human tumor necrosis factor (TNF), which selectively engages mouse TNF receptor 1; cross-linking of the B- or T-cell antigen receptors; peptidoglycan, which activates Toll-like receptor 2; and lipopolysaccharide (LPS), which stimulates Toll-like receptor 4. Consistent with these observations, RIP3-deficient mice exhibited normal antibody production after immunization with a T-dependent antigen and normal interleukin-1 beta (IL-1 beta), IL-6, and TNF production after LPS treatment. Thus, we can exclude RIP3 as an essential modulator of NF-kappa B signaling downstream of several receptor systems.
Travelling wave fault location of transmission line using wavelet transform (2002)

This paper presents a new fault location principle based on the double terminal methods of travelling waves using continuous wavelet transform (CWT). Due to the attenuation and distortion of travelling wave propagation in a transmission line, a open problem is how to define the arrival time and the propagation velocity of the travelling wave correctly. Since CWT has much better resolution for locating a transient event in time-domain, the arrival time can be defined by a characteristic point of the travelling wave extracted by a suitable continuous wavelet with the optimal dilation parameters, and the propagation velocity depends on the physical configuration of a transmission line and the optimal dilation parameters. Extensive simulation results show that the new method has a location accuracy within /spl plusmn/ one tower span in the case of various grounding resistances, different fault positions and different line configurations.
Implementing a specification for exceptional data in multilevel modeling of healthcare applications (2012)

Missing information are key issues for interoperability and semantic coherence in healthcare information systems. This paper presents the implementation of the Exceptional Package in the Multilevel Healthcare Information Modeling (MLHIM) specifications, and it describes two use cases where missing information is critical for decision-making and healthcare technology assessment.
How to Optimize the Electrostatic Interaction between a Solid Adsorbent and CO<sub>2</sub> (2014)

Pressure swing adsorption (PSA) is a promising method for an economically viable separation of CO2 from gas mixtures. One important step in developing efficient PSA separations is to choose an adsorbent with a good compromise between selectivity and working capacity. The problem can be seen as an optimization process where one searches the properties of the adsorbent that give the best trade-off between selectivity and working capacity. In a recent work we have developed a method to optimize the properties of nonpolar adsorbents for PSA separation of CO2. In this work we have extended the analysis to polar adsorbents. A simplified model of the electric field generated by the solid is used to gain a better understanding of the effect of the geometry and the magnitude of the field on the adsorption behavior of the system. General rules about optimal adsorbents for CO2 adsorption in porous solid can be drawn. These rules allow defining a strategy for the intelligent design of porous materials for CO2 separation applications.
The Downy Mildew Effector Proteins ATR1 and ATR13 Promote Disease Susceptibility in <i>Arabidopsis thaliana</i> (2007)

The downy mildew (Hyaloperonospora parasitica) effector proteins ATR1 and ATR13 trigger RPP1-Nd/WsB- and RPP13-Nd-dependent resistance, respectively, in Arabidopsis thaliana. To better understand the functions of these effectors during compatible and incompatible interactions of H. parasitica isolates on Arabidopsis accessions, we developed a novel delivery system using Pseudomonas syringae type III secretion via fusions of ATRs to the N terminus of the P. syringae effector protein, AvrRPS4. ATR1 and ATR13 both triggered the hypersensitive response (HR) and resistance to bacterial pathogens in Arabidopsis carrying RPP1-Nd/WsB or RPP13-Nd, respectively, when delivered from P. syringae pv tomato (Pst) DC3000. In addition, multiple alleles of ATR1 and ATR13 confer enhanced virulence to Pst DC3000 on susceptible Arabidopsis accessions. We conclude that ATR1 and ATR13 positively contribute to pathogen virulence inside host cells. Two ATR13 alleles suppressed bacterial PAMP (for Pathogen-Associated Molecular Patterns)-triggered callose deposition in susceptible Arabidopsis when delivered by DC3000 DeltaCEL mutants. Furthermore, expression of another allele of ATR13 in plant cells suppressed PAMP-triggered reactive oxygen species production in addition to callose deposition. Intriguingly, although Wassilewskija (Ws-0) is highly susceptible to H. parasitica isolate Emco5, ATR13Emco5 when delivered by Pst DC3000 triggered localized immunity, including HR, on Ws-0. We suggest that an additional H. parasitica Emco5 effector might suppress ATR13-triggered immunity.
Calibration for Blood Gas Determination by Gas Chromatography. (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCalibration for Blood Gas Determination by Gas Chromatography.H. Y. YeeCite this: Anal. Chem. 1965, 37, 7, 924–925Publication Date (Print):June 1, 1965Publication History Published online1 May 2002Published inissue 1 June 1965https://pubs.acs.org/doi/10.1021/ac60226a035https://doi.org/10.1021/ac60226a035research-articleACS PublicationsRequest reuse permissionsArticle Views82Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Designing a supplier database to support sourcing analysis (2013)

Nowadays, more and more business organizations emphasize the importance of competitive suppliers in their strategic benefits. On one hand, with the extension of global industrialization, there are much more suppliers available for a company than ever before, which results in the difficulty for the company to develop a proper sourcing decision. On the other hand, advanced data processing technologies can help companies improve their capability of sourcing data analysis significantly. Thus, how to design an effective supplier database to support sourcing analysis has become an essential topic in recent years. \nThis thesis aims to design a supplier database based on the theory of master data management (MDM) for processing B2B sourcing data, and the discussions are presented according to the previous research in the sourcing department of Sandvik Mining and Construction (China). The whole design was developed mainly in 5 stages. Firstly, necessary information was gathered from the company as well as some academic literature. Secondly, pre-research preparation was done by studying all the collected information. Thirdly, a framework of the database was designed out. Fourthly, more detail design was proposed in different modules, focusing on some practical issues in the existing data systems. Fifthly, the outcome of the design was discussed in a comprehensive way. \nAlthough the MDM-oriented supplier database was designed for a specific project in a company, some basic principles of the design can be adopted prevalent. However, it is necessary to claim that this design is not totally completed, still with more practical work to be done in the future. Regarding the further research in this case, more professionals from different backgrounds (i.e. IT, business, management, etc.) should be involved, and the organizational support from the company is important as well.
Synthesis and Magnetic Properties of Ultrafine Iron Particles Prepared by Pyrolysis of Carbonyl Iron (1992)

Magnetic characteristics of fine iron particles prepared by a new chemical process, were studied. In this semi-industrial process, iron pentacarbonyl, Fe(CO) 5 was used as a starting material, and it was thermally decomposed under a magnetic field. Diameter of obtained particles was between 150 and 250 Å, and the particles were aligned along the magnetic field like a necklace. The highest coercive force appeared when particle diameter was about 200 Å. To stabilize the particles, surfaces of particles were slightly oxidized before they were exposed to the open air. The saturation magnetization of treated particles was about 70% of the bulk value. Some test tapes were made by using these fine iron particles.
A NEW KIND OF CLEAN (2007)

RETURN TO ISSUEPREVNewsNEXTA NEW KIND OF CLEANSEVENTH GENERATION seeks out environmentally friendly detergent ingredientsMICHAEL MCCOYView Author Information C&EN NORTHEAST NEWS BUREAUCite this: Chem. Eng. News 2007, 85, 12, 29–31Publication Date (Print):March 19, 2007Publication History Published online29 October 2010Published inissue 19 March 2007https://pubs.acs.org/doi/10.1021/cen-v085n012.p029https://doi.org/10.1021/cen-v085n012.p029newsACS PublicationsCopyright © 2007 American Chemical SocietyArticle Views12Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Anatomy,Atmospheric chemistry Get e-Alerts
Quantitative Design and Analysis of Relay Resonators in Wireless Power Transfer System (2012)

Wireless power transfer systems are finding increasing applications which can enhance the living standard of the general public. Typical examples are wireless charging of mobile phone batteries and car batteries. Thanks to the advent of power electronics in the past few decades, some wireless charging systems are now emerging in the commercial sector. However, the transfer efficiency and transfer distance of these chargers are limiting the technology to a few specific applications only. In order to increase the transfer distance, some researchers have successfully proposed to use relay coils to improve their wireless power transfer efficiency. In this paper, the role of relay resonator is examined critically. The reported findings indicate that it is not always desirable to have relay coils in wireless charger as the relay resonator may increase, or sometimes reduce, the overall power transfer efficiency. The findings also reveal that there is an optimal position for the designer to locate the relay resonator to maximize the power transfer efficiency.
Semiconductor bridge: A plasma generator for the ignition of explosives (1987)

Small metal bridgewires are commonly used to ignite energetic powders such as pyrotechnics, propellants, and primary or secondary explosives. In this paper we describe a new means for igniting explosive materials using a semiconductor bridge (SCB). When driven with a short (20 μs), low-energy pulse (less than 3.5 mJ), the SCB produces a hot plasma that ignites explosives. The SCB, a heavily n-doped silicon film, typically 100 μm long by 380 μm wide by 2 μm thick, is 30 times smaller in volume than a conventional bridgewire. SCB devices produce a usable explosive output in a few tens of microseconds and operate at one-tenth the input energy of metal bridgewires. In spite of the low energies for ignition, SCB devices are explosively safe. We describe SCB processing and experiments evaluating SCB operation. Also discussed are the SCB vaporization process, plasma formation, optical spectra from the discharge, heat transfer mechanisms from the SCB to the explosive powders, and SCB device applications.
Densities, Viscosities, and Conductivities of Mixtures of Benzene with the Lewis Acidic Aluminum Chloride + 1-Methyl-3-ethylimidazolium Chloride Molten Salt (1996)

The densities, kinematic viscosities, and specific conductances of mixtures of benzene with the Lewis acidic room-temperature chloroaluminate molten salt aluminum chloride + 1-methyl-3-ethylimidazolium chloride (AlCl3 + MeEtimCl) were determined at 298.2 K. Benzene was added to melts containing 51.00, 60.00, and 66.67 mol % AlCl3. Simple polynomial equations were fitted to the experimental results as a function of the mass fraction of benzene. The addition of small amounts of benzene resulted in a decrease in the kinematic viscosity and an increase in the specific conductance of the mixture. However, the addition of benzene beyond 35 mass % caused the specific conductance to decrease due to a decrease in the concentration of charge-carrying ions.
An Automatic Algorithm for Segmentation of the Boundaries of Corneal Layers in Optical Coherence Tomography Images using Gaussian Mixture Model (2014)

Diagnosis of corneal diseases is possible by measuring and evaluation of corneal thickness in different layers. Thus, the need for precise segmentation of corneal layer boundaries is inevitable. Obviously, manual segmentation is time-consuming and imprecise. In this paper, the Gaussian mixture model (GMM) is used for automatic segmentation of three clinically important corneal boundaries on optical coherence tomography (OCT) images. For this purpose, we apply the GMM method in two consequent steps. In the first step, the GMM is applied on the original image to localize the first and the last boundaries. In the next step, gradient response of a contrast enhanced version of the image is fed into another GMM algorithm to obtain a more clear result around the second boundary. Finally, the first boundary is traced toward down to localize the exact location of the second boundary. We tested the performance of the algorithm on images taken from a Heidelberg OCT imaging system. To evaluate our approach, the automatic boundary results are compared with the boundaries that have been segmented manually by two corneal specialists. The quantitative results show that the proposed method segments the desired boundaries with a great accuracy. Unsigned mean errors between the results of the proposed method and the manual segmentation are 0.332, 0.421, and 0.795 for detection of epithelium, Bowman, and endothelium boundaries, respectively. Unsigned mean errors of the inter-observer between two corneal specialists have also a comparable unsigned value of 0.330, 0.398, and 0.534, respectively.