gebhart/patrepeval huggingface dataset:
Is the retrieval of high numbers of oocytes desirable in patients treated with gonadotrophin-releasing hormone analogues (GnRHa) and gonadotrophins? (1989)

Continuous administration of gonadotrophin-releasing hormone analogues (GnRHa) in patients stimulated for the purpose of IVF might have a direct effect on the ovary. We have evaluated the IVF outcome of patients treated with Buserelin and subsequently with a combination of follicle-stimulating hormone (FSH) and human menopausal gonadotrophin (HMG). Patients were divided into three groups according to the number of oocytes obtained by transvaginal ultrasound-guided follicular aspiration: group 1 (n = 35), in which 1-5 oocytes were retrieved; group 2 (n = 30), in whom 6-10 oocytes were obtained; group 3 (n = 32), in whom greater than or equal to 11 oocytes were collected. Only couples with normal semen samples at oocyte retrieval were included in this study. The dose of Buserelin employed was not different between groups. However, the amount of FSH/HMG necessary to reach an optimal response significantly (P less than 0.01) decreased as follicular development increased. The quality of the oocytes obtained was evaluated based on the appearance of the oocyte-corona-cumulus complex, fertilization rate, morphological appearance of the embryos, and implantation rate. The fertilization rate was significantly (P less than 0.01) decreased in group 3 (57.2%) in comparison with groups 1 (77.1%) and 2 (74.2%). There was no significant difference between the groups in the quality of the embryos obtained or the quality of those replaced into the uterus. The implantation rate per embryo transferred was significantly (P less than 0.05) higher in group 1 (16.5%) in comparison with groups 2 (6.6%) and 3 (8.2%).(ABSTRACT TRUNCATED AT 250 WORDS)
Low-Frequency Noise Characteristics in Strained-Si nMOSFETs (2007)

The low-frequency (LF) (1/f) noise mechanism of strained-Si nMOSFETs grown on relaxed Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> Ge <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> virtual substrates (VSs) has been investigated. It is found that the Si-cap thickness plays an important role in characterizing the 1/f noise mechanism. Ge out-diffusion effect and slight strain relaxation in Si-cap layer are responsible for the degradation of 1/f noise in strained-Si device with 10- and 20-nm-thick Si-cap, respectively. In addition, by choosing proper Si-cap thickness, experimental result shows that as Si-cap undergoes stronger tensile strain for higher Ge concentration VS, the correlated mobility fluctuation term in the modified carrier-number fluctuation model is more dominated for the 1/f noise
Towards improved biomonitoring tools for an intensified sustainable multi‐use environment (2016)

The increasing use of our environment for multiple contrasting activities (e.g. fisheries, tourism) will have to be accompanied by improved monitoring of environmental quality, to avoid transboundary conflicts and ensure long-term sustainable intensified usage. Biomonitoring approaches are appropriate for this, since they can integrate biological effects of environmental exposure rather than measure individual compound concentrations. Recent advances in biomonitoring concepts and tools focus on single-cell assays and purified biological components that can be miniaturized and integrated in automated systems. Despite these advances, we are still very far from being able to deploy bioassays routinely in environmental monitoring, mostly because of lack of experience in interpreting responses and insufficient robustness of the biosensors for their environmental application. Further future challenges include broadening the spectrum of detectable compounds by biosensors, accelerate response times and combining sample pretreatment strategies with bioassays.
Minimally invasive mitral valve repair through right minithoracotomy in the setting of degenerative mitral regurgitation: early outcomes and long-term follow-up. (2015)

MIMV repair through right minithoracotomy is a safe and reproducible procedure associated with high rate of MV repair, and excellent early postoperative and long-term results.
Experimental induction of atheroarteriosclerosis by the synergy of allergic injury to arteries and lipid-rich diet. II. Effect of repeatedly injected foreign protein in rabbits fed a lipid-rich, cholesterol-poor diet. (1973)

Rabbits fed a lipid-rich, cholesterol-poor diet and given concomitant injections of foreign protein, over a period as long as 17 months, developed in their coronary arteries both a) proliferative fibromuscular intimal thickening closely resembling the diffuse intimal thickening that commonly occurs in coronary arteries of man, and b) fatty-proliferative fibromuscular intimal thickening that closely resembles coronary atherosclerosis in man. In contrast, rabbits of another group that were concurrently fed the same diet for as long as 22 months without injections of foreign protein developed changes in arteries of their hearts that resemble neither coronary atherosclerosis nor diffuse intimal thickening in man. Fatty-proliferative changes in aortas of the first group of rabbits are strikingly greater and more closely resemble human aortic atherosclerosis than those in the latter group. In the course of the experiments, the average serum cholesterol was not significantly different in the two groups of rabbits. It was approximately 200 to 250 mg%, which is the average serum cholesterol in adult humans in the United States. These experiments support the hypothesis that the synergy of arterial injury, in particular immunologic injury, and a diet rich in lipid can lead to atherosclerosis in man.
Dual-ascent methods for large-scale multicommodity flow problems (1993)

The capacitated multicommodity network flow problem presents itself in a number of problem contexts including transportation, communication, and production. To solve the large-scale multicommodity flow problems encountered in these fields, we develop dual-ascent heuristics and a primal solution generator. The dual-ascent solutions, in addition to determining lower bounds on the optimal objective function value, provide advanced starting solutions for use with primal-based solution techniques. The primal solution generator uses the dual-ascent solution to obtain heuristically primal solutions to the multicommodity flow problems. Computational experiments performed on three test problem sets show that the dual-ascent and primal heuristic procedures typically determine nearoptimal solutions quickly. In addition, by using the dual-ascent procedure to obtain advanced starting solutions, run times for optimal multicommodity flow procedures are reduced significantly and greatly improved solutions are obtained by the new primal solution generator. © 1993 John Wiley & Sons, Inc.
Utility of the neurological examination in rats. (1980)

This study presents general observations of neurological examination in rats after various CNS manipulations. The examination consisted of neurologic reactions as described in Bures and co-workers. Subjects studied were controls, hippocampal irradiates, and animals with cerebellar lesions or midline cerebellar transplants. Utility of the procedure as an adjunct to more detailed testing is discussed.
The vehicle passive keyless entry system based on RFID (2008)

Radio Frequency Identification (RFID) technology holds great potential for vehicle entry system. The use of how RFID technology works in vehicle passive keyless entry system were introduced. This system transmit information to other electric units through CAN bus. At the same time, the system’s working principle, block diagram, circuit diagram and software flow chain are also presented.
Palladium-catalyzed syn 1,4-additions of silyl-derived carboxylates and phenoxides to cyclopentadiene monoepoxide. A stereo- and regiocontrolled route to differentially protected cis-2-cyclopentene-1,4-diols (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPalladium-catalyzed syn 1,4-additions of silyl-derived carboxylates and phenoxides to cyclopentadiene monoepoxide. A stereo- and regiocontrolled route to differentially protected cis-2-cyclopentene-1,4-diolsDonald R. Deardorff, Soroosh Shambayati, Robert G. Linde II, and Monty M. DunnCite this: J. Org. Chem. 1988, 53, 1, 189–191Publication Date (Print):January 1, 1988Publication History Published online1 May 2002Published inissue 1 January 1988https://pubs.acs.org/doi/10.1021/jo00236a039https://doi.org/10.1021/jo00236a039research-articleACS PublicationsRequest reuse permissionsArticle Views187Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Model checking for an executable subset of UML (2005)

The paper presents an approach to model checking software system designs specified in xUML (http://www.kc.com/html/xuml.html), an executable subset of UML. This approach is enabled by the execution semantics of xUML and is based on automatic translation from xUML to S/R, the input language of the COSPAN model checker (R.H. Hardin et al., 1996). Model transformations are applied to reduce the state space of the resulting S/R model that is to be verified by COSPAN. An xUML level logic for specifying properties to be checked is defined. Automated support is provided for translating properties specified in the logic to S/R representations and mapping error traces generated by COSPAN to xUML representations.
Product Positioning Under Price Competition (1990)

This paper presents a consumer-based methodology for new product pricing and positioning in the face of price competition. The price competition is modelled as a Nash equilibrium for which two complementary approaches are employed: an analytical approach of duopoly provides qualitative insights into the competitive behavior, and a numerical approach of general oligopoly provides quantitative solutions under a wide variety of market scenarios. The optimal product positioning is formulated as a Stackelberg-Nash (leader-followers) equilibrium which can be solved numerically using recent advances in the field of variational inequalities. A small example concerning analgesics is used to illustrate this methodology.
Smartphone based hand-held quantitative phase microscope using the transport of intensity equation method (2016)

In order to realize high contrast imaging with portable devices for potential mobile healthcare, we demonstrate a hand-held smartphone based quantitative phase microscope using the transport of intensity equation method. With a cost-effective illumination source and compact microscope system, multi-focal images of samples can be captured by the smartphone's camera via manual focusing. Phase retrieval is performed using a self-developed Android application, which calculates sample phases from multi-plane intensities via solving the Poisson equation. We test the portable microscope using a random phase plate with known phases, and to further demonstrate its performance, a red blood cell smear, a Pap smear and monocot root and broad bean epidermis sections are also successfully imaged. Considering its advantages as an accurate, high-contrast, cost-effective and field-portable device, the smartphone based hand-held quantitative phase microscope is a promising tool which can be adopted in the future in remote healthcare and medical diagnosis.
Biology of Female Cancers (1997)

Introduction to the Cell and Molecular Biology of Cancer, S.P. Langdon and W.R. Miller Introduction to Breast Cancer, A.P.M. Forrest Hormonal, Growth Factor, and Cytokine Control of Breast Cancer, W.R. Miller and S.P. Langdon Oncogenes and Tumor Suppressor Genes in Breast Cancer, R.A. Walker Biological Basis for Therapy in Breast Cancer, D.A. Cameron and R.C.F. Leonard Ovarian Cancer-An Introduction, H. Gabra and J.F. Smyth Hormonal, Growth Factor, and Cytokine Control of Ovarian Cancer, S.P. Langdon, B.J.B. Simpson, J.M.S. Bartlett, and W.R. Miller Oncogenes and Tumor-Suppressor Genes in Ovarian Cancer, C.M. Steel and H. Gabra Ovarian Cancer: Biological Basis of Therapy, J.S. Beesley, K.V. Ferry, S.W. Johnson, A.K. Godwin, and T.C. Hamilton Biological Strategies in the Therapy of Gynecologic Cancers, J.M. Mathis, C.Y. Muller, V.E. von Gruenigen, and D.S. Miller Endometrial Cancer: An Introduction, R.J.B. King Endometrial Carcinoma: Steroid Hormones, Growth Factors, and Cytokines, P.G. Satyaswaroop and S. Tabibzadeh Alterations of Oncogenes and Tumor-Suppressor Genes in Endometrial Cancer, A. Berchuck, A. Evans, and J. Boyd Cervical Cancer and Its Precursors-An Introduction, T.C. Wright and T.W. Park Cervical Cancer: Hormones, Growth Factors, and Cytokines, R. Leake Oncogenes and Tumor-Suppressor Genes in Cervical Cancer, C. Busby-Earle Vulval Neoplasia, G. Smart, M.J. Arends, and A. Al-Nafussi Gestational Trophoblastic Disease, G.L. Mutter Hereditary Aspects of Female Cancers, A.P. Shapter, A. Berchuck, and B.Y. Karlan
Validation, calibration, revision and combination of prognostic survival models (2000)

The problem of assessing the validity and value of prognostic survival models presented in the literature for a particular population for which some data has been collected is discussed. Methods are sketched to perform validation through 'calibration', that is by embedding the literature model in a larger calibration model. This general approach is exemplified for x-year survival probabilities, Cox regression and general non-proportional hazards models. Some comments are made on basic structural changes to the model, described as 'revision'. Finally, general methods are discussed to combine models from different sources. The methods are illustrated with a model for non-Hodgkin's lymphoma validated on a Dutch data set.
Immunoglobulin M antibodies detected by enzyme-linked immunosorbent assay and radioimmunoassay in the diagnosis of cytomegalovirus infections in pregnant women and newborn infants (1985)

Immunoglobulin M (IgM) antibodies were detected by a commercially available enzyme-Linked Immunosorbent Assay (ELISA) in 36 of 49 (73%) pregnant women with primary cytomegalovirus (CMV) infection. A positive ELISA-IgM result occurred in 10 of 13 patients (77%) assessed within 8 weeks of seroconversion. The sensitivity of the radioimmunoassay (RIA) to identify primary infection in pregnant women was comparable, 78% in general and 86% for women tested within 16 weeks of seroconversion. Of the 36 women with primary infection who had detectable IgM antibodies by ELISA, 25 (69%) were delivered of congenitally infected infants, whereas of the 13 with undetectable IgM antibodies, 7 (54%) transmitted the infection in utero. IgM antibodies were detected by ELISA in only 5 of 43 (11%) women who experienced a recurrence of CMV which either did or did not result in congenital infection. RIA was less likely to measure CMV-specific IgM in recurrent infection, inasmuch as 1 of 19 (5.2%) women with proven recurrent infection had detectable IgM antibody, giving RIA a better specificity for primary infection. Specific IgM antibodies were detected by ELISA in 42 of 61 (69%) babies congenitally infected with CMV and in 4 of 70 (5.7%) uninfected control newborn infants. The RIA was superior for diagnosis of congenital CMV infection, with a sensitivity of 89% and a specificity of 100%. The lower sensitivity of the ELISA-IgM occurred in the category of congenitally infected infants born to mothers with recurrent infection (43%), a group that is at the lowest risk of disease or to develop sequelae. This commercially available ELISA-IgM could be used in combination with a CMV-specific IgG test for monitoring women during pregnancy for primary infection.
Angiotensin Converting Enzyme in Alzheimer's Disease: Increased Activity in Caudate Nucleus and Cortical Areas (1982)

The activity of the dipeptidyl carboxypeptidase, angiotensin converting enzyme, was assayed in several brain regions of patients dying with Alzheimer's disease and compared to that of appropriately age-matched controls. Enzyme activity was found to be elevated by 44% and 41% in the medial hippocampus and parahippocampal gyrus, respectively, and by 27% and 29% in the frontal cortex (area 10 of Brodman) and caudate nucleus, respectively, in Alzheimer's disease patients. Converting enzyme activity did not differ from controls in the nucleus accumbens, substantia nigra, temporal cortex, anterior or posterior hippocampus, amydgala, and septal nuclei.
<title>Solar Reversible Energy Fluctuation Converter</title> (1983)

Although the power conversion of energy fluctuation is a basic physical concept, the theoretical analysis of the performance for all the wide ranging design options for each application, as for example, solar energy conversion, is not simple. The basic physics of the reversible energy fluctuation (REF) converter is to transfer the energy fluctuations of the hot charged particles in the first layer across the thermal barrier of the second layer to the cool rectifying diodes of the third layer with an intrinsic efficiency in a reversible cycle for independent particles that is limited by the efficiency of the Carnot cycle. Because of the questions on this surprising high efficiency, an extended analysis of each question has been made. One question is whether impractically small circuit sizes limited to a few nanometers are required. The answer is there is no limitation on circuit size and that simple REF design options exist to achieve a conversion efficiency of 85% independent of circuit sizes. Another question is whether practical amounts of power can be obtained from energy fluctuations. The answer shows the inherent ability of the REF converter to transfer energy fluctuations across the thermal barrier at a power rate orders of magnitude larger than for any practical application. As a result of finding that several feasible and practical design options are available as solutions to each question, it is reasonable to conclude that near-term production is a feasible prospect.
Binocular visual performance and summation after correcting higher order aberrations (2012)

Although the ocular higher order aberrations degrade the retinal image substantially, most studies have investigated their effect on vision only under monocular conditions. Here, we have investigated the impact of binocular higher order aberration correction on visual performance and binocular summation by constructing a binocular adaptive optics (AO) vision simulator. Binocular monochromatic aberration correction using AO improved visual acuity and contrast sensitivity significantly. The improvement however, differed from that achieved under monocular viewing. At high spatial frequency (24 c/deg), the monocular benefit in contrast sensitivity was significantly larger than the benefit achieved binocularly. In addition, binocular summation for higher spatial frequencies was the largest in the presence of subject's native higher order aberrations and was reduced when these aberrations were corrected. This study thus demonstrates the vast potential of binocular AO vision testing in understanding the impact of ocular optics on habitual binocular vision.
Capillary Critical Point of Argon, Nitrogen, Oxygen, Ethylene, and Carbon Dioxide in MCM-41 (1997)

The effect of temperature on adsorption isotherms of Ar, N2, O2, C2H4, and CO2 on mesoporous MCM-41 molecular sieves with different pore sizes (pore radius rp = 1.2, 1.4, 1.8, 2.1 nm) has been measured. The occurrence of adsorption hysteresis upon capillary condensation of these molecules in mesopores depends on their capillary critical temperatures (Tcc), which are far below the corresponding bulk critical temperatures (Tc). In accord with theoretical predictions of confined geometry effects on the criticality of fluids in narrow pores, a plot of (Tc − Tcc)/Tc against d/rp for Ar, N2, O2, and C2H4 seems to form a single straight line passing through the origin, where d is the molecular diameter. The data for CO2 deviates from this relationship. These results are compared with critical point shifts of fluids in conventional mesoporous adsorbents with an interconnected network of pores available in the literature.
Immunological cross-reactivity between human tripeptidyl peptidase II and fibronectin (1990)

Tripeptidyl peptidase II (TPP II) is a large intracellular exopeptidase with an active site of the subtilisin type. Affinity-purified hen antibodies against human erythrocyte TPP II cross-reacted with fibronectin in an immunoblot analysis. Furthermore, antibodies against human fibronectin cross-reacted with TPP II. Antibodies against a 65 kDa cell-binding fragment of fibronectin specifically reacted with TPP II, whereas antibodies against the collagen-binding domain, the main heparin-binding domain or the N-terminal fibrin-binding domain did not react. Moreover, the affinity-purified antibodies against TPP II reacted with a 105 kDa cell-binding fragment of fibronectin but not with the fibrin-binding domain or the collagen-binding domain. When native TPP II was dissociated into smaller units through dialysis against a dilute Tris buffer, it could be digested by chymotrypsin into three stable fragments of 70 kDa, 42 kDa and 20 kDa. It could be demonstrated that the 42 kDa fragment was specifically recognized by antibodies against the 65 kDa cell-binding fragment of fibronectin. Furthermore, labelling with di-[3H]isopropyl phosphorofluoridate and N-terminal sequence determination showed that the 70 kDa fragment contained the active-site serine residue. In conclusion, our findings suggest that one domain of the TPP II molecule bears structural resemblance to a cell-binding fragment of fibronectin.
Bolivia: instruction through interactive radio. (1989)

The Education Development Center in Bolivia is developing and testing a new application for interactive radio instruction (IRI) to teach health in primary schools. The project is funded by USAID and has been undertaken to help the Bolivian government include health education in primary schools as part of a strategy to reduce child mortality. Each radio health program will be broadcast weekly for school children in twenty-minute segments. The broadcasts and complementary post-broadcast activities will give special emphasis to child survival topics such as oral rehydration therapy and nutrition. Special features include IRI scripts which simulate interaction between the radio teacher and the students, new topics introduced in a systematic way engaging students in problem-solving activities, and extensive oral and written student participation. Complementary IRI program materials will include take-home exercises designed to involve family participation, and teachers' guides to provide teachers with practical hands-on activities to strengthen children's understanding of basic health concepts. Short, in-service training sessions will prepare teachers to facilitate radio classes and carry out post-broadcast activities with students. The potential of IRI to improve student and teacher understanding of health and nutrition is only beginning to be recognized.