gebhart/patrepeval huggingface dataset:
Magnetically Directed Self-Assembly of Electrospun Superparamagnetic Fibrous Bundles to Form Three-Dimensional Tissues with a Highly Ordered Architecture (2011)

Engineering three-dimensional (3D) cell-dense tissues with a well-organized structure remains a challenge in tissue engineering. In this study, highly oriented fibrous bundles, consisted of composite fibers of poly(L-lactide-co-glycolide)/superparamagnetic iron oxide nanoparticles, were fabricated using an electrospinning technique. The magnetic properties of the fabricated fibrous bundles were examined by a vibrating sample magnetometer and a superconducting quantum interference device; the results demonstrate that the fabricated fibrous bundles revealed superparamagnetic behavior without magnetic hysteresis. After seeding C2C12 myoblasts on the fibrous bundles, cells were grown along the direction of the underlying fibers (cell rods), an aligned pattern similar to those in native skeletal muscle tissues. When treated with the differentiation medium, myoblasts were fused together and formed multinucleated myotubes. As soon as applying an external magnetic field, the cell rods can spontaneously response to the magnetic control and self-assemble into 3D tissues with a highly ordered architecture. These findings demonstrate that the magnetically susceptible fibrous bundles not only can serve as a functional unit providing the topographic cue for cell orientation, but also can be magnetically manipulated for the creation of 3D cell-dense constructs. This technique may be applied to various cell types and scaffold configurations, thus advancing the design of engineered tissues that more closely replicate native tissues.
엽채류의 MA 포장에 따른 이취관련물질 축적 및 품질변화 (2011)

The study has been carried to investigate the accumulation of off-flavor compounds and qualty change in leafy vegetable MA packaging. The results were as follows. Respiration of lettuce, spinach, and sesame was double in both 50㎛ and 75㎛ treatments at 10th day of storage when compared with 40㎛ treatment. However, ethylene had no significant difference among treatments. Concentration of acetaldehyde, one of off-flavor compounds were 1.5~2 times higher in 50㎛ and 75㎛ treatments than 40㎛ at 10th day of storage, which showed the close relationship with the thickness of packaging material. Weigh loss decreased as the storage time increased regardless of packaging material. Chlorophyll content of spinach and sesame gradually decreased as the storage time increased, which was a similar trend in all packaging treatments. However, lettuce showed a little higher chlorophyll content at storage period than right after harvesting period.
Thin film deposition of lanthanum manganite perovskite by the ALE process (1999)

Deposition of thin films of LaMnO 3 from β-diketonate-type (thd) precursors and ozone in an ALE reactor has been demonstrated. At low temperatures, the Mn-O growth from the Mn(thd) 3 precursor is retarded by the growth of the La-O deposit. By tuning of the pulsing ratio, full control of the stoichiometry of the deposited film is achieved in the temperature interval 300-400 °C. In this temperature range, the composition set by the pulsing ratio is transferred, within a few percent accuracy, to the deposited thin film. Indications for an ‘ALE window’ are found around 250-300 °C. Amorphous LaMnO 3 films could be deposited at temperatures as low as 250 °C, however, the deposition of crystalline films requires temperatures above 350 °C. X-Ray diffraction analyses show that the crystalline LaMnO 3 film was of the rhombohedral type with a=5.46(2) Å and α=60.28(10)°.
Sonovoltammetry: Heterogeneous Electron-Transfer Processes with Coupled Ultrasonically Induced Chemical Reaction. The "Sono-EC" Reaction (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSonovoltammetry: Heterogeneous Electron-Transfer Processes with Coupled Ultrasonically Induced Chemical Reaction. The "Sono-EC" ReactionRichard G. Compton, John C. Eklund, and Stephen D. PageCite this: J. Phys. Chem. 1995, 99, 12, 4211–4214Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/j100012a049https://doi.org/10.1021/j100012a049research-articleACS PublicationsRequest reuse permissionsArticle Views175Altmetric-Citations55LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
2H-6 Tissue Doppler Gated (TDOG) Real-Time Stitching in Three-Dimensional Fetal Echocardiography (2006)

Three-dimensional (3D) fetal echocardiography is a promising technique for assessment of fetal cardiac structure and function, but suffers from lower temporal resolution than ultrasound imaging in two dimensions. Real-time, ECG-gated volume stitching is a known method in adult echocardiography, used to increase the spatial and/or temporal resolution of volumetric cardiac scans. In fetal echocardiography however, stitching has been impossible due to lack of ECG data for gating. A real-time gating signal for fetal echocardiography is suggested in this work. An ultrasound system was set up to acquire 3D gray-scale data and 3D tissue Doppler data simultaneously, with only the gray-scale data visible to the sonographer. Derived from the Doppler data, a gating signal, denoted the tissue Doppler gating (TDOG) signal, was calculated in real-time. The TDOG trigger events were used to induce changes in the geometry setup of the 3D gray-scale scan, ensuring that data from consecutive cardiac cycles were captured from separate parts of the total volumetric scan. A scan setup with six disjoint subvolumes was used, and the system could in real-time assemble and display volume data sets with data from the six most resent heart cycles. In-vivo data ware recorded from 5 pregnant women with fetuses aged 20-24 weeks, utilizing a matrix transducer with a center frequency of 3 MHz. TDOG signals from several different tissue Doppler scan geometries are presented: 5deg and 10deg planar sector scans and 8deg times 8deg volumetric scans. Volumetric, assembled scans acquired with TDOG gated stitching are shown, and both good and poor match between subvolumes are demonstrated. We conclude that the TDOG technique provides real-time gating of fetal cardiac cycles and it can be used to acquire stitched, 3D fetal echocardiographic data with high frame rate
Variance components estimation : mixed models, methodologies and applications (1997)

The Study of Variation. One-Way Classification. Two-Way Cross-Classification. Randomized Blocks. BIBDs and Latin Squares. Nested Classifications. Maximum Likelihood Estimation. The MINQUE and MIVQUE. Non-Negative Estimation of Variance Components. Confidence Intervals. Genetic and Environmental Effects.
Fading-noise suppressed OFDR using optical frequency comb source and tunable delay line (2011)

A delay shift averaging optical frequency domain reflectometry using optical frequency comb source and tunable delay line to suppress the fading noise is proposed. Better reflectivity-resolution is demonstrated compared to using a single-wavelength laser.
A File Format for the Exchange of Images in the Internet (1992)

This document defines a standard file format for the exchange of fax-like black and white images within the Internet. It is a product of the Network Fax Working Group of the Internet Engineering Task Force (IETF).
Catalytic Staudinger Reduction at Room Temperature (2019)

We report an efficient catalytic Staudinger reduction at room temperature that enables the preparation of a structurally diverse set of amines from azides in excellent yields. The reaction is based on the use of catalytic amounts of triphenylphosphine as a phosphine source and diphenyldisiloxane as a reducing agent. Our catalytic Staudinger reduction exhibits a high chemoselectivity, as exemplified by reduction of azides over other common functionalities, including nitriles, alkenes, alkynes, esters, and ketones.
Transduction of Human CD34 <sup>+</sup> Repopulating Cells with a Self-Inactivating Lentiviral Vector for SCID-X1 Produced at Clinical Scale by a Stable Cell Line (2012)

Self-inactivating (SIN)-lentiviral vectors have safety and efficacy features that are well suited for transduction of hematopoietic stem cells (HSCs), but generation of vector at clinical scale has been challenging. Approximately 280 liters of an X-Linked Severe Combined Immunodeficiency Disorder (SCID-X1) SIN-lentiviral vector in two productions from a stable cell line were concentrated to final titers of 4.5 and 7.2×10(8) tu/ml. These two clinical preparations and three additional development-scale preparations were evaluated in human CD34(+) hematopoietic cells in vitro using colony forming cell (CFU-C) assay and in vivo using the NOD/Lt-scid/IL2Rγ(null) (NSG) mouse xenotransplant model. A 40-hour transduction protocol using a single vector exposure conferred a mean NSG repopulating cell transduction of 0.23 vector genomes/human genome with a mean myeloid vector copy number of 3.2 vector genomes/human genome. No adverse effects on engraftment were observed from vector treatment. Direct comparison between our SIN-lentiviral vector using a 40-hour protocol and an MFGγ(c) γ-retroviral vector using a five-day protocol demonstrated equivalent NSG repopulating cell transduction efficiency. Clonality survey by linear amplification-mediated polymerase chain reaction (LAM-PCR) with Illumina sequencing revealed common clones in sorted myeloid and lymphoid populations from engrafted mice demonstrating multipotent cell transduction. These vector preparations will be used in two clinical trials for SCID-X1.
Cloning and functional analysis of the P97 swine cilium adhesin gene of Mycoplasma hyopneumoniae (1997)

Colonization of the swine respiratory tract by Mycoplasma hyopneumoniae is accomplished by specific binding to the cilia of the mucosal epithelial cells. Previous studies have implicated a 97-kDa outer membrane-associated protein, P97, that appeared to mediate this interaction. In order to further define the role of P97 in adherence to porcine cilia, the structural gene was cloned and sequenced, and the recombinant products were analyzed. Monoclonal antibodies were used to identify recombinant clones in a genomic library expressed in an opal suppressor host because of alternate codon usage by mycoplasmas. The gene coding for P97 was then identified by Tn1000 mutagenesis of recombinant clones. DNA sequence analysis revealed an open reading frame coding for a 124.9-kDa protein with a hydrophobic transmembrane spanning domain. The N-terminal sequence of purified P97 mapped at amino acid position 195 of the translated sequence, indicating that a processing event had occurred in M. hyopneumoniae. Both recombinant P97 protein expressed in an Escherichia coli opal suppressor host and M. hyopneumoniae bound specifically to swine cilia, and the binding was inhibited by heparin and fucoidan, thus supporting the hypothesis that P97 was actively involved in binding to swine cilia in vivo.
Mitochondrial Fission and Fusion Mediators, hFis1 and OPA1, Modulate Cellular Senescence (2007)

The number and morphology of mitochondria within a cell are precisely regulated by the mitochondrial fission and fusion machinery. The human protein, hFis1, participates in mitochondrial fission by recruiting the Drp1 into the mitochondria. Using short hairpin RNA, we reduced the expression levels of hFis1 in mammalian cells. Cells lacking hFis1 showed sustained elongation of mitochondria and underwent significant cellular morphological changes, including enlargement, flattening, and increased cellular granularity. In these cells, staining for acidic senescence-associated beta-galactosidase activity was elevated, and the rate of cell proliferation was greatly reduced, indicating that cells lacking hFis1 undergo senescence-associated phenotypic changes. Reintroduction of the hFis1 gene into hFis1-depleted cells restored mitochondrial fragmentation and suppressed senescence-associated beta-galactosidase activity. Moreover, depletion of both hFis1 and OPA1, a critical component of mitochondrial fusion, resulted in extensive mitochondrial fragmentation and markedly rescued cells from senescence-associated phenotypic changes. Intriguingly, sustained elongation of mitochondria was associated with decreased mitochondrial membrane potential, increased reactive oxygen species production, and DNA damage. The data indicate that sustained mitochondrial elongation induces senescence-associated phenotypic changes that can be neutralized by mitochondrial fragmentation. Thus, one of the key functions of mitochondrial fission might be prevention of the sustained extensive mitochondrial elongation that triggers cellular senescence.
SELECTIVE INHIBITION OF THE CALORIGENIC ACTIVITIES OF CERTAIN THYROXINE ANALOGUES WITH CHRONIC THIOURACIL TREATMENT IN RATS (1960)

Journal Article SELECTIVE INHIBITION OF THE CALORIGENIC ACTIVITIES OF CERTAIN THYROXINE ANALOGUES WITH CHRONIC THIOURACIL TREATMENT IN RATS Get access NEIL R. STASILLI, NEIL R. STASILLI 1Warner-Lambert Research Institute Morris Plains, New Jersey Search for other works by this author on: Oxford Academic Google Scholar ROBERT L. KROC, ROBERT L. KROC 1Warner-Lambert Research Institute Morris Plains, New Jersey Search for other works by this author on: Oxford Academic Google Scholar RAY EDLIN RAY EDLIN 1Warner-Lambert Research Institute Morris Plains, New Jersey Search for other works by this author on: Oxford Academic Google Scholar Endocrinology, Volume 66, Issue 6, 1 June 1960, Pages 872–885, https://doi.org/10.1210/endo-66-6-872 Published: 01 June 1960 Article history Published: 01 June 1960 Received: 05 June 1960
Fall Detection Based on Body Part Tracking Using a Depth Camera (2014)

The elderly population is increasing rapidly all over the world. One major risk for elderly people is fall accidents, especially for those living alone. In this paper, we propose a robust fall detection approach by analyzing the tracked key joints of the human body using a single depth camera. Compared to the rivals that rely on the RGB inputs, the proposed scheme is independent of illumination of the lights and can work even in a dark room. In our scheme, a pose-invariant randomized decision tree algorithm is proposed for the key joint extraction, which requires low computational cost during the training and test. Then, the support vector machine classifier is employed to determine whether a fall motion occurs, whose input is the 3-D trajectory of the head joint. The experimental results demonstrate that the proposed fall detection method is more accurate and robust compared with the state-of-the-art methods.
Band structure engineering and doping of wide gap II–VI superlattices (1995)

It is shown that the free hole concentration for nitrogen doped ZnSe/ZnTe short period superlattices with a given average Te content of 15% can be increased from 1016 to 1019 cm−3 by just increasing the SL period from 2.5 to 4.5 nm. This behavior can be understood in terms of a model that assumes a pinning of the Fermi level at an energetic position that is fixed with respect to the vacuum level. The model can be applied to other II–VI superlattices, and alternative cladding layers for blue laser diodes are proposed that should exhibit significantly higher p-doping levels than the currently used ZnMgSSe claddings.
Moderate to Severe Periodic Limb Movement Disorder in Childhood and Adolescence (1999)

The purpose of this study is to review clinical features of children with moderate to severe Periodic Limb Movement Disorder (PLMD). Because of our interest in both Restless Legs Syndrome (RLS) and Attention-Deficit Hyperactivity Disorder (ADHD), many of our patients had one or both of these conditions. We did a retrospective review of 129 children and adolescents who were found to have Periodic Limb Movements in Sleep (PLMS) > 5/hour of sleep. Sixty five had PLMS of 5-10/hour of sleep, 48 had PLMS of 10-25/hour of sleep and 16 had PLMS > 25/hour of sleep. One hundred and seventeen of the original 129 had ADHD. Stimulant medication did not seem to play a role in the production of PLMS. In only 25 of the 129 cases did parents note the presence of PLMS before being specifically asked to look, and even after specific instructions to look, PLMS were not noted by the parents in 39 patients. The sub-group of 16 children and adolescents--6 female, 10 male (average age 11.1 years--range 6-17 years) with moderate to severe PLMS > 25/hour of sleep are described in more detail. Fifteen of the 16 patients had ADHD. Four of the 16 had RLS and 10 of 13 patients for whom a family history was available had a parent with RLS. Two of the 16 patients had their PLMS initially misdiagnosed as seizures. Sleep disturbance was present in all 16 patients and 7 of the 16 had daytime somnolence which resolved with dopaminergic medications. To our knowledge this is the first clinical series of moderate to severe PLMS in children and adolescents to be fully described in the literature.
Multilayered Electride Ca<sub>2</sub>N Electrode via Compression Molding Fabrication for Sodium Ion Batteries (2017)

Pursuing for novel electrode materials is significant for the progress of sodium ion batteries (SIBs). Here, a multilayered electride prepared by simple thermal decomposition of solid Ca<sub>3</sub>N<sub>2</sub>, namely Ca<sub>2</sub>N, is introduced as a new anode material of SIBs for the first time, and a compression molding electrode fabricated by pressing Ca<sub>2</sub>N powder into nickel foam is applied to protect Ca<sub>2</sub>N from trace moisture and oxygen. The as-prepared electrode delivers an initial discharge capacity of 1110.5 mAh g<sup>-1</sup> and a reversible discharge capacity of ∼320 mAh g<sup>-1</sup>. These results suggest that Ca<sub>2</sub>N has a great potential for sodium ion batteries.
Mechanism of negative-bias-temperature instability (1991)

Although negative-bias-temperature instability in metal-oxide-semiconductor integrated circuits has been minimized empirically, the exact mechanism is unknown. We argue in this paper that the mechanism of negative-bias-temperature instability can be modeled by a first-order electrochemical reaction between hydrogenated trivalent silicon, a neutral water-related species located in the oxide near the Si-SiO2 interface, and holes at the silicon surface to form neutral trivalent silicon and a positively charged water-related species. To show that such a reaction describes the phenomenon, we show that (1) water must be present in the oxide near the Si-SiO2 interface, (2) induced interface and oxide-fixed charge densities are equal, (3) the saturation interface-trap and oxide-fixed charge densities depend on the initial hole concentration at the silicon surface or aging field, (4) the buildup of these charge densities follows first-order reaction kinetics, and (5) time constants for this charge buildup are independent of aging field. The measurements which are done to demonstrate these features combine room-temperature charge measurement using the Q-C method with current measurements during accelerated aging.
Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease (2017)

Tolvaptan resulted in a slower decline than placebo in the estimated GFR over a 1-year period in patients with later-stage ADPKD. (Funded by Otsuka Pharmaceuticals and Otsuka Pharmaceutical Development and Commercialization; REPRISE ClinicalTrials.gov number, NCT02160145 .).
Tool path planning based on endpoint build-in optimization in rapid prototyping (2011)

Filling defects, which appear on the tool path ends as the existence of the control precision error of enabling components (laser, nozzle) and movement acceleration and deceleration of moving components, cause serious problems in appearance quality of parts in a number of welding-based rapid prototyping processes such as plasma welding, laser welding, and fused deposition modeling. This paper presents a novel tool path planning algorithm based on endpoint build-in optimization, moving the two path endpoints with filling defects from the part surface into the internal region. Experiments in fused deposition modeling processes show that the algorithm effectively addresses this issue, and is reliable and efficient.
Multisite Monoclonal Immunoassay for Dengue Viruses: Detection of Viraemic Human Sera and Interference by Heterologous Antibody (1986)

A monoclonal radioimmunoassay (RIA) was developed for detection of dengue virus in infected cell culture fluids and blood samples from dengue patients. Antibodies used to construct the RIA were selected on the basis of high binding avidity, the demonstration of synergism in competitive binding assays and empirical trials with different antibody combinations. Optimal binding of all four dengue virus serotypes was achieved by use of a flavivirus group-reactive and a dengue virus complex-reactive antibody as radiolabelled probe. A 'simultaneous sandwich' format and prolonged (18 h) incubation at 37 degrees C yielded optimal results. The limit of sensitivity of the RIA for detection of dengue type 2 virus was 2.7 log10 mosquito 50% infectious doses (MID50). The assay was tenfold more sensitive for dengue type 2 than for dengue types 1 and 3 viruses and 100-fold more sensitive than for dengue type 4 virus. Specificity, assessed using over 500 disease control human sera, was increased by addition of monoclonal anti-tetanus blocking antibodies, resulting in a false positive rate of only 0.2%. Heterologous dengue virus antibodies were shown to inhibit the RIA in assays performed with artificial immune complexes. Acute phase human sera containing 10(4.2) to 10(7.6) MID50 but no detectable antigen by RIA, were also shown to inhibit binding of the homologous dengue virus serotype; this effect was attributed to heterologous antibody from a prior infection. Among 116 viraemic sera from dengue patients, the RIA was positive in 43 to 47% of patients with dengue type 1, 2 or 3 infections but in only 10% of the dengue type 4 cases. Virus was more frequently detected in cases of primary infection (54%) than in cases of superinfection (16%). Despite the limitations imposed by immunological interference, the antigen capture RIA appears useful as a rapid diagnostic technique for dengue surveillance.