gebhart/patrepeval huggingface dataset:
Application considerations for PWM inverter-fed low-voltage induction motors (1992)

Pulse-width modulation (PWM) inverters should be applied with special consideration for low-voltage induction motor operation. The power supplied to the motor by a PWM inverter has some adverse effects, which are described. These effects include increased heating, high peak voltages, and increased audible noise. The impact these effects have on a given application is presented. Specific areas discussed include: motor noise caused by different power transistor types and switching strategies; additional motor heating produced by PWM invertor power and the operating speed-torque range; the effects of PWM inverter-produced harmonics on the low-voltage induction motor; PWM inverter designs and their effect on motor insulation systems; and voltage transients generated by semiconductor switching technologies employed in PWM inverters.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Dysregulated transcriptional and post-translational control of DNA methyltransferases in cancer (2014)

Cancer is a leading cause of death worldwide. Aberrant promoter hypermethylation of CpG islands associated with tumor suppressor genes can lead to transcriptional silencing and result in tumorigenesis. DNA methyltransferases (DNMTs) are the enzymes responsible for DNA methylation and have been reported to be over-expressed in various cancers. This review highlights the current status of transcriptional and post-translational regulation of the DNMT expression and activity with a focus on dysregulation involved in tumorigenesis. The transcriptional up-regulation of DNMT gene expression can be induced by Ras-c-Jun signaling pathway, Sp1 and Sp3 zinc finger proteins and virus oncoproteins. Transcriptional repression on DNMT genes has also been reported for p53, RB and FOXO3a transcriptional regulators and corepressors. In addition, the low expressions of microRNAs 29 family, 143, 148a and 152 are associated with DNMTs overexpression in various cancers. Several important post-translational modifications including acetylation and phosphorylation have been reported to mediate protein stability and activity of the DNMTs especially DNMT1. In this review, we also discuss drugs targeting DNMT protein expression and activation for therapeutic strategy against cancer.
The Geometry of Multiple Images: The Laws that Govern the Formation of Multiple Images of a Scene and Some of Their Applications (2002)

From the Publisher:
with contributions from Theo Papadopoulo


Over the last forty years, researchers have made great strides in elucidating the laws of image formation, processing, and understanding by animals, humans, and machines. This book describes the state of knowledge in one subarea of vision, the geometric laws that relate different views of a scene. Geometry, one of the oldest branches of mathematics, is the natural language for describing three-dimensional shapes and spatial relations. Projective geometry, the geometry that best models image formation, provides a unified framework for thinking about many geometric problems relevant to vision. The book formalizes and analyzes the relations between multiple views of a scene from the perspective of various types of geometries. A key feature is that it considers Euclidean and affine geometries as special cases of projective geometry.
Images play a prominent role in computer communications. Producers and users of images, in particular three-dimensional images, require a framework for stating and solving problems. The book offers a number of conceptual tools and theoretical results useful for the design of machine vision algorithms. It also illustrates these tools and results with many examples of real applications.
Evaluation of chemokine and cytokine profiles in osteoblast progenitors from umbilical cord blood stem cells by BIO‐PLEX technology (2007)

We have used cytokine protein array to analyze the secretion of cytokines from an osteoblastic clone derived from human umbilical cord blood mesenchymal stem cells (MSCs) cultured in an osteogenic differentiation medium. The analysis demonstrated the unexpected ability of osteoblast committed cells and their early progenitors to produce significant amounts of a range of soluble immune mediators without in vitro exposure to clinically relevant bacterial pathogens. The cells were expanded and their osteogenic potential analyzed over 45 days of culture was revealed by the expression of osteoblast-specific markers (alkaline phosphatase and Runx2), and by matrix mineralization. Over this culture period, the cells secreted particularly high levels of IL-8, MCP-1 and VEGF, but did not express IL-2, IL-7, IL-17, eotaxin, G-CSF and IFN-gamma. These findings should encourage the use of human umbilical cord blood as a potential stem cells source for bone regeneration.
Hydrogels: Covalently Adaptable Elastin‐Like Protein–Hyaluronic Acid (ELP–HA) Hybrid Hydrogels with Secondary Thermoresponsive Crosslinking for Injectable Stem Cell Delivery (Adv. Funct. Mater. 28/2017) (2017)

In article number 1605609, Sarah C. Heilshorn and co-workers describe an injectable hydrogel. Design via dynamic covalent crosslinking and thermoresponsive physical crosslinking enhances gel stability, provides mechanical protection during cell transplantation, and stem cell differentiation support. The image shows that cells can achieve cell-cell and cell-matrix interactions within the gel. Artwork designed by Nick Suhar.
Functional Properties of Guar Proteins (1981)

ABSTRACT Water and fat absorption, emulsification capacity (E.C.), foaming capacity (F.C.), and foam stability (F.S.) of guar meal and protein isolate have been determined and compared with those of soybean meal and isolate. Guar meal had lower water absorption capacity, similar fat absorption capacity and greater F.S. and E.C. than soybean meal. Guar protein isolate (GPI) had lower water absorption capacity but higher fat absorption capacity than soy protein isolate (SPI). The foaming capacity and emulsification capacity were similar at all pH's except around pH 4. However the foam stability of GPI was greater than that of SPI.
An Architectural Design for Self-Reporting E-Health Systems (2019)

Worldwide, public healthcare is challenged to deliver consistent and cost-efficient services. The cost of healthcare is increasing primarily due to growing populations and more expensive treatment. Health facilities in many countries are reaching their full operational capacity, and their resources %of these hospitals are less than what is required to deliver the expected quality of care. Under these circumstances, ICT has a major role to play in mitigating the growing need for hospital care. In this paper, we present a cloud-based interoperable architecture built on the top of Service-Oriented Architecture (SOA) for Internet-based treatment where patients can directly interact with underlying healthcare systems such as Electronic Health Records (EHRs). Based on this architecture, we also present a prototype for screening and monitoring of mental and neurological health morbidities. The proposed solution is based on the healthcare interoperability standard, HL7 FHIR, that enables healthcare providers to assess and monitor patients condition in a secure environment.
An automatic singing skill evaluation method for unknown melodies using pitch interval accuracy and vibrato features (2006)

This paper presents a method of evaluating singing skills that does not require score information of the sung melody. This requires an approach that is different from existing systems, such as those currently used for Karaoke systems. Previous research on singing evaluation has focused on analyzing the characteristics of singing voice, but were not aimed at developing an automatic evaluation method. The approach presented in this study uses pitch inter- val accuracy and vibrato as acoustic features which are indepen- dent from specific characteristics of the singer or melody. The ap- proach was tested by a 2-class (good/poor) classification test with 600 song sequences, and achieved an average classification rate of 83.5%. The aim of this study is to explore a method of automatic evalua- tion of singing skills without score information. Our interest lies in identifying the criteria that human subjects use in judging the quality of singing for unknown melodies, using acoustic features which are independent from specific characteristics of the singer or melody. Such evaluation systems can be useful tools for im- proving singing skills, and also can be applied to broadening the scope of music information retrieval and singing voice synthesis. Previous work related to singing skills include those based on a control model of fundamental frequency (F0) trajectory (1), gen- eral characteristics (2, 3), as well as work on automatic discrimi- nation of singing and speaking voices (4), and acoustic differences between trained and untrained singers' voices (5, 6, 7). None of these work have gone as far as presenting an automatic evaluation method. This paper presents a singing skill evaluation scheme based on pitch interval accuracy and vibrato, which are regarded as features that function independently from the individual characteristics of singer or melody. To test the validity of these features, an experi- ment of automatic evaluation of singing performance by a 2-class classification (good/poor) was conducted. The following sections describe our approach and the exper- imental results of its evaluation. Section 2 presents discussion of features. Section 3 describes the classification experiment and its evaluation. Section 4 concludes the paper, with discussion on di- rections for future work.
Two-Dimensional Electronic Spectroscopy Reveals the Dynamics of Phonon-Mediated Excitation Pathways in Semiconducting Single-Walled Carbon Nanotubes (2012)

Electronic two-dimensional Fourier transform (2D-FT) spectroscopy is applied to semiconducting single-walled carbon nanotubes and provides a spectral and time-domain map of exciton-phonon assisted excitations. Using 12 fs long pulses, we resolve side-bands above the E(22) transition that correspond with the RBM, G, G', 2G and other multiphonon modes. The appearance of 2D-FT spectral cross-peaks explicitly resolves discrete phonon assisted population transfer that scatters excitations to the E(22) (Γ-pt) state, often through a second-order exciton-phonon coupling process. All 2D-FT peaks exhibit a strong peak amplitude modulation at the G-band period (21 fs) which we show originates from an impulsive stimulated Raman process that populates a ground-state G-band vibrational coherence over a 1.3 ps phonon lifetime.
Cyclic AMP Receptor Protein and RhaR Synergistically Activate Transcription from the <scp>l</scp> -Rhamnose-Responsive <i>rhaSR</i> Promoter in <i>Escherichia coli</i> (2005)

The Escherichia coli rhaSR operon encodes two AraC family transcription activator proteins, RhaS and RhaR, which regulate expression of the l-rhamnose catabolic regulon in response to l-rhamnose availability. RhaR positively regulates rhaSR in response to l-rhamnose, and RhaR activation can be enhanced by the cyclic AMP (cAMP) receptor protein (CRP) protein. CRP is a well-studied global transcription regulator that binds to DNA as a dimer and activates transcription in the presence of cAMP. We investigated the mechanism of CRP activation at rhaSR both alone and in combination with RhaR in vivo and in vitro. Base pair substitutions at potential CRP binding sites in the rhaSR-rhaBAD intergenic region demonstrate that CRP site 3, centered at position -111.5 relative to the rhaSR transcription start site, is required for the majority of the CRP-dependent activation of rhaSR. DNase I footprinting confirms that CRP binds to site 3; CRP binding to the other potential CRP sites at rhaSR was not detected. We show that, at least in vitro, CRP is capable of both RhaR-dependent and RhaR-independent activation of rhaSR from a total of three transcription start sites. In vitro transcription assays indicate that the carboxy-terminal domain of the alpha subunit (alpha-CTD) of RNA polymerase is at least partially dispensable for RhaR-dependent activation but that the alpha-CTD is required for CRP activation of rhaSR. Although CRP requires the presence of RhaR for efficient in vivo activation of rhaSR, DNase I footprinting assays indicated that cooperative binding between RhaR and CRP does not make a significant contribution to the mechanism of CRP activation at rhaSR. It therefore appears that CRP activates transcription from rhaSR as it would at simple class I promoters, albeit from a relatively distant position.
Overview of RFID-based indoor positioning technology (2012)

Abstract: Radio frequency identification (RFID) technology was originally invented for military uses. From 1980s, commercial RFID products started to be available and they were mainly applied in areas of supply chains, transport, manufacturing, personnel access, animal tagging, toll collection etc. Nowadays, RFID has been recognised as an emerging technology for ubiquitous positioning (UP), especially in an indoor environment. The development and implementation of RFID-based positioning technology are very fast, whilst according to the literature, little comprehensive review and convinced assessment for the latest RFID technology have been conducted, and some of the main features of the latest RFID technology have rarely or unclearly been presented in the literature, for example, the longest reading range of RFID systems, the smallest tag size and overall commercial application fields. This paper provides an overview of state-of-the-art RFID technology, particularly for the purpose of indoor positioning. It includes a review of historical and current development of RFID technology and its applications, an evaluation of up-to-date RFID-based positioning techniques and their performance as well as a prediction of future trends of RFID-based indoor positioning techniques. This paper can be a valuable guidance and solution for researchers and other end users to better understand RFID and critical factors considered on system requirements, hardware selection and positioning performance for various applications.
DYNAMIC RIDESHARE OPTIMIZED MATCHING PROBLEM (2012)

This dissertation develops a Dynamic Rideshare Optimized Matching (DROM) model and solution that is aimed at identifying suitable matches between passengers requesting rideshare services with appropriate drivers available to carpool for credits and HOV lane privileges. DROM receives passengers and drivers' information and preferences continuously over time and maximizes the overall system performance subject to ride availability, capacity, rider and driver time window constraints, and detour and relocation distances while considering users' preferences. The research develops a spatial, temporal, and hierarchical decomposition solution strategy that leads to the heuristic solution procedure. Three-Spherical Heuristic Decomposition Model (TSHDM). Quality and validity tests for the TSHDM algorithm are done by comparison of results between the exact and implemented algorithm solutions and major sensitivity analyses using the technique of Regression Analysis on all of the related parameters in the model are conducted to thoroughly investigate the properties of the proposed model and solution algorithm. A case study is constructed to analyze the model and TSHDM behaviors on a road network of northwest metropolitan area of Baltimore city. The study shows that however DROM is a very complicated and challenging problem from both mathematical formulation and solution algorithm perspectives, it is possible to implement a dynamic rideshare system using appropriate technical tools and social networking media. Major sensitivity analysis conducted on several parameters and variables affecting the model shows that most influencing factors for the rate of success in the rideshare system are, in order of importance: number of participating drivers, number of stops, area size, and number of participating riders. The study also shows rate of success for the rideshare system is highly dependent to the matched routes connecting directly points of origin and destination for participating riders and also increasing the number of connections from one to two which requires two consecutive change of rides for a rider has the least impact on the rate of success.
Band gap of GaN films grown by molecular-beam epitaxy on GaAs and GaP substrates (1995)

There has been controversy concerning the energy gap of the cubic (zinc-blende) form of the wide-gap semiconductor GaN. Measurements are reported of the band gaps of both hexagonal (wurtzite) and cubic thin films deposited by a modified molecular-beam-epitaxy process on (001) GaAs and GaP substrates. The important difference from conventional MBE lies in the method of supplying nitrogen to the growing film. Here a rf nitrogen plasma source operating at 13 MHz is used. The structure of the films was monitored by x-ray diffraction and controlled by the addition of an As beam which results in growth of the cubic form—otherwise films grow with the hexagonal structure. The band gaps were measured at room temperature by optical reflectivity, as evidenced by the sharp reduction in interference oscillations as the photon energy approached the band edge, and confirmed by the observation of band-edge photoluminescence. The results can be summarized as Eg=3.42±0.02 eV for the hexagonal and 3.22±0.02 eV for the cubic form. The observation of films containing mixed hexagonal and cubic phases, which may have led to earlier errors in band-gap measurements, is also reported.
Antineoplastic Agents. V. The Aromatic System of Podophyllotoxin (Part B)<sup>1-3</sup> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntineoplastic Agents. V. The Aromatic System of Podophyllotoxin (Part B)1-3George R. Pettit, Michael F. Baumann, and K. N. RangammalCite this: J. Med. Chem. 1962, 5, 4, 800–808Publication Date (Print):July 1, 1962Publication History Published online1 May 2002Published inissue 1 July 1962https://pubs.acs.org/doi/10.1021/jm01239a014https://doi.org/10.1021/jm01239a014research-articleACS PublicationsRequest reuse permissionsArticle Views133Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
What aspect is needed for a better understanding of tilt sickness (1996)

Motion sickness is a physiological result of sensory conflict with spatial orientation. There are two approaches to motion sickness models: descriptive model approach and predictive model approach. The former is comprehensive but less applicable for practical engineering use. The latter presents useful forms for engineering but has narrow application in practice because it concerns only accelerative inputs, neglecting other inputs. A more comprehensive and practical model is necessary to solve the motion sickness problems in real transportation. One way to meet this need is to make a quantitative model of sensory conflict with spatial orientation. Efforts in this aspect will lead to a better understanding of and even a solution to the motion sickness problem in tilt trains.
Security analysis of cryptographically controlled access to XML documents (2008)

Some promising recent schemes for XML access control employ encryption for implementing security policies on published data, avoiding data duplication. In this article, we study one such scheme, due to Miklau and Suciu [2003]. That scheme was introduced with some intuitive explanations and goals, but without precise definitions and guarantees for the use of cryptography (specifically, symmetric encryption and secret sharing). We bridge this gap in the present work. We analyze the scheme in the context of the rigorous models of modern cryptography. We obtain formal results in simple, symbolic terms close to the vocabulary of Miklau and Suciu. We also obtain more detailed computational results that establish security against probabilistic polynomial-time adversaries. Our approach, which relates these two layers of the analysis, continues a recent thrust in security research and may be applicable to a broad class of systems that rely on cryptographic data protection.
Review of optoelectronic oscillators based on modelocked lasers and resonant tunneling diode optoelectronics (2011)

Optoelectronic oscillators can provide low noise oscillators at radio frequencies in the 0.5-40 GHz range and in this paper we review two recently introduced approaches to optoelectronic oscillators. Both approaches use an optical fibre feedback loop. One approach is based on passively modelocked laser diodes and in a 40 GHz oscillator achieves up to 30 dB noise reduction. The other approach is based on resonant tunneling diode optoelectronic devices and in a 1.4 GHz oscillator can achieve up to 30 dB noise reduction.
Andrographolide interferes with binding of nuclear factor‐<i>κ</i>B to DNA in HL‐60‐derived neutrophilic cells (2005)

1. Andrographolide, the major active component from Andrographis paniculata, has shown to possess anti-inflammatory activity. Andrographolide inhibits the expression of several proinflammatory proteins that exhibit a nuclear factor kappa B (NF-kappaB) binding site in their gene. 2. In the present study, we analyzed the effect of andrographolide on the activation of NF-kappaB induced by platelet-activating factor (PAF) and N-formyl-methionyl-leucyl-phenylalanine (fMLP) in HL-60 cells differentiated to neutrophils. 3. PAF (100 nM) and fMLP (100 nM) induced activation of NF-kappaB as determined by degradation of inhibitory factor B alpha (IkappaB alpha) using Western blotting in cytosolic extracts and by binding to DNA using electrophoretic mobility shift assay (EMSA) in nuclear extracts. 4. Andrographolide (5 and 50 microM) inhibited the NF-kappaB-luciferase activity induced by PAF. However, andrographolide did not reduce phosphorylation of p38 MAPK or ERK1/2 and did not change IkappaB alpha degradation induced by PAF and fMLP. 5. Andrographolide reduced the DNA binding of NF-kappaB in whole cells and in nuclear extracts induced by PAF and fMLP. 6. Andrographolide reduced cyclooxygenase-2 (COX-2) expression induced by PAF and fMLP in HL-60/neutrophils. 7. It is concluded that andrographolide exerts its anti-inflammatory effects by inhibiting NF-kappaB binding to DNA, and thus reducing the expression of proinflammatory proteins, such as COX-2.