gebhart/patrepeval huggingface dataset:
Venous thromboembolism (1997)

Patients with risk factors for VTE and developing signs or symptoms remotely consistent with DVT or PE should undergo formal testing. Ultrasound and IPG have good sensitivity and specificity in symptomatic DVT. V/Q lung scans should be obtained in all patients with suspected PE or proven DVT. A prior clinical assessment of probability, based on risk factors, history, physical examination, chest film, and arterial blood gas analysis, can aid in the interpretation of V/Q scans. Normal scans exclude PE. High-probability scans confirm PE if the clinical probability is at least intermediate. Nondiagnostic scans are common, but diagnosis in such cases can be aided by noninvasive leg studies. Heparin therapy should be started when there is suspicion of VTE. To avoid recurrence, a therapeutic aPTT of 1.5 to 2.5 times the control rate should be achieved as soon as possible after the diagnosis of VTE is confirmed. Thrombolytics are reserved for hemodynamically compromised patients. Warfarin should be administered to achieve an INR of 2.0 to 3.0 and should be continued for at least 3 months in patients with low risk of recurrence and probably for at least 6 months in all other patients.
Nanosized Mesoporous Silica Coatings on Ceramic Foams:  New Hierarchical Rigid Monoliths (2007)

Silica-based rigid monoliths exhibiting a trimodal hierarchical pore system have been successfully prepared through coating of a ceramic foam (CF) with sub-micro-/nanometric mesoporous particles (as building blocks). We have selected a bimodal porous silica, denoted as UVM-7 (a nanometric version of the well-known MCM-41 materials), consisting of small aggregates of nanometric surfactant-assisted mesoporous particles. A colloidal suspension of this material in water is used to coat through successive impregnation cycles the CF surface. The small intraparticle mesopore system (with pore diameters around 2−3 nm) is due to the supramolecular templating effect of the surfactant. Textural large-mesopores/macropores (in the 20−70 nm range) have their origin in the interparticle UVM-7 voids. The large macrocellular macropores are due to the CF support. The resulting monoliths present a good and homogeneous coverage level. Moreover, these composites display better mechanic properties than those of related silica self-supported monoliths.
The high incidence of left atrial appendage thrombosis in patients on maintenance haemodialysis (2003)

The incidence of intracardiac thrombosis in haemodialysis patients has not been studied. Here we determined the incidence in end-stage renal disease patients on maintenance haemodialysis.Transoesophageal echocardiography was performed in 215 patients (125 males, 90 females; mean age 60 +/- 9 years). Any potential candidate with current or past chronic or intermittent atrial fibrillation or with cardiovascular diseases was excluded from the study.Thrombi were found in the left atrial appendages in 71 out of 215 subjects (33%). Based on multiple logistic regression analyses, the probability of finding a thrombus was found to be increased in patients on chronic antiplatelet therapy (odds ratio 4.268) and in those with diabetes mellitus and a low haematocrit (</=0.3; odds ratio 7.173). Other clinical parameters, including gender, age, duration of haemodialysis, blood pressure, left ventricular dimension, smoking habit or type of anticoagulation during dialysis, were not associated with the incidence of left atrial appendage thrombosis.Maintenance haemodialysis patients have a high incidence of left atrial appendage thrombosis. Either chronic use of antiplatelet drugs or the background conditions requiring antiplatelet therapy, and the concomitant presence of diabetes mellitus and a low haematocrit may be involved in left atrial appendage thrombosis.
Scenarios Of Disaster, Visions of Liberation (2004)

As the planet spirals ever deeper into social and natural disaster, with all things becoming ever more tightly knit into the tentacles of global capitalism, there is an urgent need for new maps and compasses to help steer us into a viable mode of existence. Karl Marx's 1843 call for a "ruthless criticism of everything existing" has never been more urgent and appropriate, but all too often today critique is merely academic, stratospheres away from concrete action and progressive social policies. Yet, social critique and change in the slaughterhouse of capitalism needs to be guided and informed by powerful descriptions of what is -- the degraded forfeiture of human potential in a world where over a billion people struggle for mere existence -- but also by bold new visions of what can be, imaginative projections of how human beings might harmoniously relate to one another and the living/dying earth
Fluid snacks to help persons with type 1 diabetes avoid late onset postexercise hypoglycemia (2000)

These data show that whole milk and sports drinks that are designed for both quick (sport drink A) and long lasting (sport drink B) nutrient replenishment can be used by persons with type 1 diabetes in an effort to avoid LOPEH.
Research on Mobile Location Service Design Based on Android (2009)

Android platform is a new generation of smart mobile phone platform launched by Google. Android provides the support of mobile map and location service, which is probably a concern of vast numbers of developers. So far, the development of mobile map and location applications is complex and difficult, and is often required to pay high copyright fees to map makers. Android is free and open, providing an easy-to-use development kit containing flexible map display and control functions. This paper introduces the architecture and component models of Android, and analyzes the anatomy of an Android application including the functions of Activity, Intent Receiver, Service, Content Provider, and etc. Based on Android, the design method of a location-based mobile service is then presented. The design example shows that it's so easy to implement self-location, to draw the driving trace, to perform query and to flexibly control the real-time map on Android.
Confirmation of Isolated Cu<sup>2+</sup> Ions in SSZ-13 Zeolite as Active Sites in NH<sub>3</sub>-Selective Catalytic Reduction (2012)

NH3-Selective Catalytic Reduction (NH3-SCR) is a widely used technology for NOx reduction in the emission control systems of heavy duty diesel vehicles. Copper-based ion exchanged zeolites and in particular Cu-SSZ-13 (CHA framework) catalysts show both exceptional activity and hydrothermal stability for this reaction. In this work, we have studied the origin of the SCR activity of Cu-SSZ-13 as evidenced from a combination of synchrotron-based and laboratory techniques. Synchrotron-based in situ XAFS/XRD measurements were used to provide complementary information on the local copper environment under realistic NH3-SCR conditions. Crucial then to the catalytic activity of Cu-SSZ-13 is the local environment of the copper species, particularly in the zeolite. Cu-SSZ-13 contains mononuclear Cu2+ species, located in the face of the double-6-ring subunit of the zeolite after calcination where it remains under reaction conditions. At lower temperatures (with low activity), XAFS and XRD data revealed a conformational change in the local geometry of the copper from a planar form toward a distorted tetrahedron as a result of a preferential interaction with NH3. This process appears necessary for activity, but results in a stymieing of activity at low temperatures. At higher temperatures, the Cu2+ possess a local coordination state akin to that seen after calcination.
Lubricants and functional fluids from renewable sources (1998)

Focuses on oleochemicals, a natural alternative to mineral oils for use in liquid lubricants, metal working coolants, quenchants and hydraulic fluids. Natural oil based products generally have many advantages over mineral oils, including lower volatility, better inherent lubricity, higher viscosity index, higher bulk modulus, better fire resistance and better solvency. Details the manufacturing process.
Absence of genetic alteration at codon 531 of the human c-src gene in 479 advanced colorectal cancers from Japanese and Caucasian patients. (1999)

Activation of c-src, a cellular human gene homologous in sequence to the v-src gene of Rous sarcoma virus, had been thought to play an important role in the progression of several types of human cancers, without having undergone any genetic changes. However, recently truncating mutations at codon 531 of the c-src gene were reported in 12% of the advanced colon cancers, and it was also demonstrated that this change was activating, transforming, tumorigenic, and metastasis promoting. To investigate whether the codon 531-specific mutation could be involved in the carcinogenesis of colorectal cancer in the Japanese and Caucasian populations, we examined a total of 479 advanced colorectal cancers from 421 Japanese patients (46 of them with liver or lung metastases) and from 58 Caucasian patients (11 of them with liver metastases). Using the PCR-RFLP assay and additional single-strand conformation polymorphism analysis, we detected no genetic alteration in any of the advanced colorectal cancers. Our results suggest that the codon 531-specific mutational activation of c-src is unlikely to play a significant role in the malignant progression of colorectal cancers among most Japanese and Caucasian patients.
Aberrant Splicing and Premature Termination of Transcription of the FVIII Gene as a Cause of Severe Canine Hemophilia A: Similarities with the Intron 22 Inversion Mutation in Human Hemophilia (2002)

We have identified the causative mutation in the hemophilia A dog colony at Queen's University, Canada and have observed a striking similarity with the intron 22 inversion found in approximately 45% of severely affected hemophilia A patients. The canine hemophilia A phenotype arises from aberrant splicing and premature termination of transcription of the FVIII gene, resulting in a polyadenylated transcript lacking exons distal to 22 and terminating with a novel sequence element (NSE). In dogs and other species including humans, this NSE is present in low copy number. One copy of these sequences in the canine genome is within intron 22 and reveals differences in the hybridization banding patterns between normal and hemophilic DNA, suggestive of a large genomic rearrangement. The mutation mechanism may not be uncommon, as identical mutant transcripts were isolated from two hemophilia A littermates that are unrelated to the Queen's colony and from hemophiliac dogs in the colony at Chapel Hill.
Glutaredoxin from Rabbit Bone Marrow (1989)

A glutaredoxin was purified from rabbit bone marrow, and its amino acid sequence was determined by high performance tandem mass spectrometry. The sequences of peptides generated by digestion with trypsin alone or in combination with thermolysin were determined from their collision-induced dissociation (CID) mass spectra. Alignment of these sequences and additional sequence information were obtained from the collision-induced dissociation mass spectra of peptides obtained from digestion of the intact protein with Staphylococcus aureus V8 protease and alpha-chymotrypsin. The resulting sequence of 106 amino acids is as follows: Ac-Ala-Gln-Glu-Phe-Val-Asn-Ser-Lys-Ile-Gln-Pro-Gly-Lys-Val-Val-Val-Phe- Ile-Lys-Pro-Thr-Cys-Pro-Tyr-Cys-Arg-Lys-Thr-Gln-Glu-Ile-Leu-Ser-Glu-Leu- Pro-Phe - Lys-Gln-Gly-Leu-Leu-Glu-Phe- Val-Asp-Ile-Thr-Ala-Thr-Ser-Asp-Met-Ser-Glu-Ile- Gln-Asp-Tyr-Leu-Gln-Gln-Leu-Thr-Gly-Ala-Arg- Thr-Val-Pro-Arg-Val-Phe-Leu-Gly-Lys-Asp-Cys-Ile- Gly-Gly-Cys-Ser-Asp-Leu-Ile-Ala-Met-Gln-Glu-Lys- Gly-Glu-Leu-Leu-Ala-Arg-Leu-Lys-Glu-Met-Gly- Ala-Leu-Arg-Gln. This glutaredoxin strongly resembles the corresponding calf and pig proteins (known as glutaredoxin and thioltransferase, respectively) with respect to its primary structure and enzymatic activity as a GSH:disulfide thioltransferase, an activity also found for the glutaredoxin from Escherichia coli. However, rabbit glutaredoxin was not active as a hydrogen donor for the reduction of ribonucleotides in the presence of the ribonucleotide reductases from rabbit bone marrow, Lactobacillus leichmannii, and Corynebacterium nephridii.
Multi-modal biochip for simultaneous, real-time measurement of adhesion and electrical activity of neurons in culture (2012)

Recent evidence suggests that integrin-mediated adhesion of neurons has immediate functional implications for learning and memory. In addition, adhesion of neurons to artificial substrates often determines the effectiveness and life of implants in the brain and peripheral nervous system. In this study, we present a novel biochip capable of simultaneous, quantitative, real-time monitoring of integrin-mediated adhesion and electrophysiology of primary neurons in vitro. The proposed technology combines acoustic micro-resonators capable of tracking changes in mechanics of the adhering neuronal layer, and microelectrode arrays for recording extracellular unit activity. Our results showed in four different experimental paradigms that the acoustic sensor response to adhering cells is correlated to integrin-mediated adhesion and that the micro-sensor is capable of monitoring the dynamics of neuronal adhesion over a period of 9 days. Finally, using our unique dual measurement platform, we performed simultaneous, real-time measurement of integrin-mediated adhesion and single cell electrophysiology in a neuronal culture. The sensitivities of the micro-resonators were 4–5 orders of magnitude greater than the sensitivity of the macro-scale resonators in response to adhering neurons. This multi-functional sensor platform offers insight into the interplay between integrin-mediated adhesion and neural function on a temporal resolution beyond any currently available experimental method and can therefore potentially lead to novel discoveries on the interactions between neuronal adhesion and function.
Sonographic diagnosis of intraperitoneal free air (2011)

Detection of intraperitoneal free air is important for the diagnosing of life-threatening conditions in patients with acute abdominal pain. Point-of-care ultrasound is an extension of the clinical examination in patients presenting with acute abdomen. Failure of sonographers to detect intraperitoneal free air was clinically considered as a limitation of abdominal ultrasound. It is now increasingly appreciated that ultrasound may detect intraperitoneal free air. Emergency physicians should be familiar with the sonographic features of intraperitoneal free air which may be essential to recognize bowel perforation. Herein we review the literature on the sonographic findings of intraperitoneal free air and the technical manoeuvres that can improve clinicians' detection of intraperitoneal free air using point-of-care ultrasound.
Automatic identification and delineation of germ layer components in H&E stained images of teratomas derived from human and nonhuman primate embryonic stem cells (2010)

We present a methodology for the automatic identification and delineation of germ-layer components in H&E stained images of teratomas derived from human and nonhuman primate embryonic stem cells. A knowledge and understanding of the biology of these cells may lead to advances in tissue regeneration and repair, the treatment of genetic and developmental syndromes, and drug testing and discovery. As a teratoma is a chaotic organization of tissues derived from the three primary embryonic germ layers, H&E teratoma images often present multiple tissues, each of having complex and unpredictable positions, shapes, and appearance with respect to each individual tissue as well as with respect to other tissues. While visual identification of these tissues is time-consuming, it is surprisingly accurate, indicating that there exist enough visual cues to accomplish the task. We propose automatic identification and delineation of these tissues by mimicking these visual cues. We use pixel-based classification, resulting in an encouraging range of classification accuracies from 74.9% to 93.2% for 2- to 5-tissue classification experiments at different scales.
Code selection approach for partitioned cyclic code shift keying to improve multinet capability (2015)

In this paper, we propose a new code selection approach for partitioned cyclic code shift keying (PCCSK) to improve the multinet capability of Joint Tactical Information Distribution Systems (JTIDS). The multinet capability of JTIDS enables concurrent operations in battle fields by allowing simultaneous data transmission and reception. PCCSK is a spread spectrum technique that supports various data rates and improves the data rate of JTIDS. The existing approach to PCCSK employs Reed Solomon (RS) code selection, and allows the dissemination of multiple access interference from the contaminated pulse to other pulses, and degrades the multinet capability. To prevent this error propagation, the proposed code selection approach restricts the RS symbol to be transmitted within one pulse. Simulation results show that the waveforms obtained using the proposed scheme outperform the previous waveforms including the JTIDS waveform with respect to both the multinet capability and the data rate.
Sulfonanilides. II. Analogs of Catecholamines (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSulfonanilides. II. Analogs of CatecholaminesA. A. Larsen, William A. Gould, Herbert R. Roth, William T. Comer, Robert H. Uloth, K. W. Dungan, and P. M. LishCite this: J. Med. Chem. 1967, 10, 3, 462–472Publication Date (Print):May 1, 1967Publication History Published online1 May 2002Published inissue 1 May 1967https://pubs.acs.org/doi/10.1021/jm00315a037https://doi.org/10.1021/jm00315a037research-articleACS PublicationsRequest reuse permissionsArticle Views178Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Submicrometer resolution replication of relief patterns for integrated optics (1974)

We report on three techniques for replicating relief patterns in dielectric materials for use as substrates for planar integrated optical circuits: embossing with a metal die; casting from a metal die; and casting from a rubber mold. Techniques for overcoating the substrates with light-guiding films and filling of grooves are also described. Measured losses in sheet film guides were ≤0.5 dB/cm. Guiding was also observed in narrow light guides fabricated by each technique. Embossing is the simplest process, but for small-scale production the casting processes are simpler to implement.
Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread. (1983)

Between 31 July and 6 October 1979, 34 cases of Ebola virus disease (22 of which were fatal) occurred among five families in a rural district of southern Sudan; the disease was introduced into four of the families from a local hospital. Chains of secondary spread within the family units, accounting for 29 cases resulted from direct physical contact with an infected person. Among all persons with such contact in the family setting, those who provided nursing care had a 5.1-fold increased risk of infection, emphasizing the importance of intimate contact in the spread of this disease. The absence of illness among persons who were exposed to cases in confined spaces, but without physical contact, confirmed previous impressions that there is no risk of airborne transmission. While the ecology of Ebola virus is unknown, the presence of anti-Ebola antibodies in the sera of 18% of persons who were unassociated with the outbreak suggests that the region is an endemic focus of Ebola virus activity.
81% Conversion efficiency in frequency-stable continuous-wave parametric oscillation (1995)

We have studied doubly resonant parametric oscillation in the regime of maximum conversion efficiency. A monolithic MgO:LiNbO3 resonator with a threshold of 28 mW, pumped by a frequency-doubled Nd:YAG laser, was employed. With an active frequency-stabilization scheme, single-mode operation without mode hops at 105 mW combined signal and idler output power was achieved at a pump power four times above threshold, with a conversion efficiency of 81%. Excellent agreement between theory and experiment was found for the dependence of efficiency and depletion on pump power. The efficiency and the nearly complete pump depletion of 94% were limited only by imperfect mode matching of the pump wave and by the small cavity losses.
On Performing and Explaining Linguistic Actions (1971)

Journal Article On Performing and Explaining Linguistic Actions Get access Quentin Skinner Quentin Skinner Christ's College, Cambridge Search for other works by this author on: Oxford Academic Google Scholar The Philosophical Quarterly, Volume 21, Issue 82, January 1971, Pages 1–21, https://doi.org/10.2307/2217566 Published: 01 January 1971
Real-time Players Movement Monitoring on Basketball Game using UWB Multidrop Ranging and Trilateration (2019)

Player movement data is used by the coach or team manager to analyze the condition of each player and plan the best strategy for the match. In general, localization of existing players uses a GPS or either an image processing. However, GPS has a drawback that it cannot be used indoor, while image processing requires high-speed cameras and also affected by its attacking angle and lighting factors in capturing players' positions. UWB (Ultra-Wide Band) is a low energy radio signal modulation technology for short-distance communication with high bandwidth in most radio wave spectrums. Applications of UWB radio have been used in everyday life, including positioning. DWM1000 is one of the devices that use UWB technology. This research applies DWM1000 in such position monitoring of basketball players' movement in the field. DWM1000 is a point to point ranging device, therefore for multiple node positioning, a multidrop technique is used between the three anchor nodes and five player-nodes. In addition, to overcome incomplete ranging and outlier positioning data, moving average filtering is applied in the trilateration software as preprocessing.
Targeting the PDGF signaling pathway in tumor treatment (2013)

Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important functions in the regulation of growth and survival of certain cell types during embryonal development and e.g. tissue repair in the adult. Overactivity of PDGF receptor signaling, by overexpression or mutational events, may drive tumor cell growth. In addition, pericytes of the vasculature and fibroblasts and myofibroblasts of the stroma of solid tumors express PDGF receptors, and PDGF stimulation of such cells promotes tumorigenesis. Inhibition of PDGF receptor signaling has proven to useful for the treatment of patients with certain rare tumors. Whether treatment with PDGF/PDGF receptor antagonists will be beneficial for more common malignancies is the subject for ongoing studies.