gebhart/patrepeval huggingface dataset:
Surfactant-mediated epitaxy of relaxed low-doped Ge films on Si(001) with low defect densities (2005)

Fully relaxed, high-quality Ge layers were grown directly on Si(001) substrates by surfactant-mediated epitaxy at high temperature with large Sb flux. We attribute the low dislocation densities in our films to an abrupt strain relief via the formation of a regular array of 90° dislocations at the interface during the initial, microrough stage of growth. This mechanism of abrupt strain relaxation occurs exclusively under high Sb coverage at temperatures ∼700°C. The high growth temperature also enhances Sb segregation leading to a low background doping level of only (3–4×1016)cm−3. Thus, we regard surfactant-mediated epitaxy of relaxed Ge on Si(001) as a promising candidate for device application.
Reversible click chemistry at the service of macromolecular materials. 2. Thermoreversible polymers based on the Diels‐Alder reaction of an A‐B furan/maleimide monomer (2010)

A novel structure was synthesized from renewable resources, bearing a furan and a masked maleimide as terminal moieties. Its thermal deprotection generated in situ the Diels-Alder (DA) A-B monomer, which was polymerized (forward DA) and then depolymerized (retro DA) in several cycles, as a function of the medium temperature. The ensuing linear polyadduct represents the first thermally reversible macromolecular material prepared from a furan-maleimide A-B monomer.
UPTAKE OF AMINO ACIDS IN BOTTOM FERMENTATIONS (1969)

The net uptake of amino acids in full-scale brewery fermentations with a strain of Saccharomyces carlsbergensis at 8–9° C. has been followed by analysing amino acids in fermenting wort and beer. The amino acids are usually taken up very incompletely and their uptake follows a certain order, not very different from that observed by British authors using top yeast fermenting at 15° C. The order is not quite constant, however; particularly the uptake of arginine and of ammonia are subject to variations. The amino acids can be divided, according to their rate of absorption and degree of utilization, into three clear-cut groups. The results suggest that it is the system allowing entry of amino acids into the cell that is of prime importance and that this is not capable of regulating the uptake to the demand of amino acids as building blocks for yeast protein. The results are considered in the light of recent investigations on amino acid permeases of yeast, and the metabolic roles of the most rapidly absorbed amino acids, serine, asparagine, glutamine, and threonine, are discussed.
A comparison of voltage mode soft switching methods for PWM converters (2002)

A comparison study was conducted to characterize the loss mechanisms, component stresses, and overall efficiencies of a group of voltage mode soft switching PWM methods including two improvement circuits developed at UCI. All soft switching methods in the selected group allow zero voltage turn-on and turn-off of the main switch and utilize a single auxiliary switch with some resonant components. Advantages and disadvantages were identified for each method. Experimental verification for each soft switching method were provided.
The Herero and Their Land (1907)

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Network management in a large-scale OSI-based campus network using SNMP (2003)

The authors expand on their experience in a practical network management system by using the simple network management protocol (SNMP) in the context of a large-scale open systems interconnection (OSI)-based campus-network. Various aspects of network management are examined and the importance of time is shown. The network management infrastructure comprises intelligent, time-synchronized agents and expert managers. Agents are deployed to collect information about the network segments to which they are attached. The expert manager talks to the agents and gathers relevant network information which is used in conjunction with a network knowledge base, to reconstruct the overall network traffic characteristic, to evaluate the status of the network and to take/suggest some action. The model allows some global control, monitoring and management without installing agents on all elements connected to the network. The use of time labels and narrow time windows enables the manager to obtain a reasonably accurate picture of the network status. The introduction of composite time-labeled objects reduces the burden of management traffic on the network.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis (2007)

Constituents in rosemary have shown a variety of pharmacological activities for cancer chemoprevention and therapy in in vitro and in vivo models. In order to further explore the chemopreventive properties of crude extracts of rosemary (Rosmarinus officinalis L), we studied its anti-proliferative property on several human cancer cell lines and its antioxidant and anti-inflammatory properties in vitro in a mouse RAW 264.7 macrophage/monocyte cell line. Our study shows that crude ethanolic rosemary extract (RO) has differential anti-proliferative effects on human leukemia and breast carcinoma cells. The 50% inhibitory concentration (IC50) was estimated at 1/700, 1/400, 1/150 and 1/500 dilutions, for the HL60, K562, MCF7 and MDA-MB-468 cells, respectively. Non-cytotoxic concentrations of RO at 1/1000 dilution minimally induced HL60 cell differentiation into granulocyte lineage at 9.5+/-2.2% compared to 2.8+/-0.8% in the untreated control (p<0.001), and did not induce HL60 cell differentiation into monocyte/macrophage lineage. The 6-hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid (Trolox) equivalent antioxidant capacity assay showed that RO has substantial antioxidant activity with RO at 1/10 and 1/5 dilutions having 8.1 and 12.6 microM Trolox equivalents, respectively. RO at non-cytotoxic 1/2000 and 1/1000 dilutions did not affect nitric oxide (NO) production by non-stimulated RAW 264.7 cells. However, at the same dilutions RO significantly reduced NO production by lipopolysaccharide (LPS)-activated cells in a dose-dependent manner from 32.6+/-2.3 microM in the LPS-activated cells to 19.2+/-2.2 microM (p<0.01), and 7.7+/-1.2 microM (p<0.001), respectively. RT-PCR analyses showed that RAW 264.7 cells treated with 1/1000 and 1/500 dilutions for 5 h did not affect TNFalpha, IL-1beta, iNOS and COX-2 mRNA expression in these cells when compared to the untreated controls, nor did the 1/1000 dilution of RO affect TNFalpha, IL-1beta, iNOS and COX-2 mRNA expression in the LPS-activated cells. At 1/500 dilution, RO significantly reduced IL-1beta (p<0.01) and COX-2 (p<0.05) mRNA expression and non-significantly reduced TNFalpha and iNOS mRNA expression in the LPS-activated cells. In view of the chemopreventive potentials, further studies are needed to explore other biological properties of this popular spice used by many cultures in the world.
Mechanism of hepatocellular dysfunction during sepsis: the role of gut-derived norepinephrine (review). (2000)

Despite major advances in the management of trauma victims, the incidence of sepsis has increased significantly over the past two decades. The increasingly high morbidity and mortality associated with sepsis could be attributed to the fact that early alterations of cellular functions are not recognized, thereby leading to delayed or inadequate treatment of the septic patient. In this regard, studies have demonstrated that hepatocellular function is depressed early after the onset of sepsis. Due to its major role in metabolism and host defense mechanisms, it is becoming increasingly evident that the liver is an important organ in the development of multiple organ dysfunction during sepsis. Mediators which are released from the gut have been implicated in initiating hepatocellular dysfunction via the release of inflammatory cytokines such as TNF-alpha by Kupffer cells, the resident macrophages present in the hepatic sinusoids. Kupffer cells, by virtue of their location in the mainstream of splanchnic blood flow, are positioned to receive a constant exposure to gut-derived mediators known to activate macrophages. In this review article, we will first describe the animal model of cecal ligation and puncture which has led to our understanding of the consequences of sepsis. We will then discuss the occurrence of hepatocellular dysfunction during early sepsis. The mechanism responsible for such a deleterious alteration in organ function, focusing especially on the role of gut-derived norepinephrine and its effect on TNF-alpha release by Kupffer cells, will be specifically discussed. Moreover, we will discuss potential approaches for modulating Kupffer cell inflammatory cytokine release and improving hepatocellular function during sepsis.
Synthesis of aryl-substituted 1,3- and 1,4-diazocine derivatives (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of aryl-substituted 1,3- and 1,4-diazocine derivativesReinhard Sarges and James R. TretterCite this: J. Org. Chem. 1974, 39, 12, 1710–1716Publication Date (Print):June 1, 1974Publication History Published online1 May 2002Published inissue 1 June 1974https://pubs.acs.org/doi/10.1021/jo00925a026https://doi.org/10.1021/jo00925a026research-articleACS PublicationsRequest reuse permissionsArticle Views332Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cellular and Humoral Immunogenicity of Hamster Polyomavirus-Derived Virus-Like Particles Harboring a Mucin 1 Cytotoxic T-Cell Epitope (2008)

In this study, we examined hamster polyomavirus (HaPyV) major capsid protein VP1-derived virus-like particles (VLPs) as a carrier for a human tumor-associated cytotoxic T lymphocyte (CTL) epitope. The VP1 tolerated the insertion of an HLA-*A2-restricted CTL epitope from human mucin 1 (MUC1) into two sites independently and simultaneously, without interfering with assembly of chimeric VLPs. Chimeric VLPs did not differ in the entry pathway or maturation potential of human dendritic cells (hDCs) compared to unmodified VLPs. Recently we demonstrated that immunization of BALB/c mice with chimeric VLPs harboring two MUC1 insertions resulted in the generation of MUC1-specific monoclonal antibodies. Here we demonstrate that the monoclonal antibodies generated react specifically with human tumor cells. Co-cultivation of chimeric VLP-primed hDCs with autologous peripheral blood leukocytes resulted in the activation of MUC1 epitope-specific CD8(+) T cells. This was evidenced by IFN-gamma secretion of an expanded MUC1-specific CD8(+) T-cell pool. The induction of epitope-specific T cells in a human in vitro model and of murine MUC1-reactive antibodies in vivo indicate the potential of chimeric HaPyV VP1-derived VLPs as a delivery vehicle for immunotherapeutic targets.
The surgical treatment of Ebstein's malformation (1996)

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Capillary electrophoretic separation of amino acids: Fraction collection (1991)

Abstract A simple method is described which enables solutes to be collected at an electrically isolated exit after they have been separated by a free solution capillary electrophoretic system. The method is illustrated by the separation of dansyl amino acids using multiple separation capillaries.
The Performance of Indian Banks During Financial Liberalization (2003)

This paper provides new empirical evidence on the impact of financial liberalization on the performance of Indian commercial banks. The analysis focuses on examining the behavior and determinants of bank intermediation costs and profitability during the liberalization period. The empirical results suggest that ownership type has a significant effect on some performance indicators and that the observed increase in competition during financial liberalization has been associated with lower intermediation costs and profitability of the Indian banks.
CD133 <sup>+</sup> neural stem cells in the ependyma of mammalian postnatal forebrain (2008)

The postnatal forebrain subventricular zone (SVZ) harbors stem cells that give rise to olfactory bulb interneurons throughout life. The identity of stem cells in the adult SVZ has been extensively debated. Although, ependymal cells were once suggested to have stem cell characteristics, subsequent studies have challenged the initial report and postulated that subependymal GFAP(+) cells were the stem cells. Here, we report that, in the adult mouse forebrain, immunoreactivity for a neural stem cell marker, prominin-1/CD133, is exclusively localized to the ependyma, although not all ependymal cells are CD133(+). Using transplantation and genetic lineage tracing approaches, we demonstrate that CD133(+) ependymal cells continuously produce new neurons destined to olfactory bulb. Collectively, our data indicate that, compared with GFAP expressing adult neural stem cells, CD133(+) ependymal cells represent an additional-perhaps more quiescent-stem cell population in the mammalian forebrain.
Editing tools for 3D medical imaging (1991)

A set of tools called MPR Edit (multiplanar reconstruction editor) is presented. Designed like a paint and drawing program for 3-D data sets, MPR Edit allows the interactive creation of shapes that define volumes of interest in images of medical data. The implementation of MPR Edit is described, and examples of its use are given. Clinical applications are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Expression of the C3d/EBV receptor and of other cell membrane surface markers is altered upon HIV-1 infection of myeloid, T, and B cells. (1990)

Human cell lines (the T-cell lines H9, Jurkat, and HUT102, the myeloid lines U937 and HL60, and the Raji B cell line) were infected with HIV-1. HIV-1 antigen could be detected by immunofluorescence analysis in more than 50% of T cells and myeloid cells 15 days after infection. Infection of Raji cells took more than 2-3 months. Studies of cell surface marker expression revealed remarkable changes after HIV-1 infection of Raji cells: expression of CR2 (C3d/EBV receptor, CD19, CD20, CD22, CD23, CD10, and surface IgM) were highly reduced, in the case of CR2 and membrane-IgM from 100 to 0%, whereas levels of CD37 and CD38 remained unaltered by HIV-1 infection. U937 cells showed a reduction of CD4 expression from 14 to 5% after HIV-1 infection; the CR3 expression slightly increased from 25 to 30%. In contrast, HLA-DR was only expressed (21%) after HIV-1 infection but not in uninfected U937 cells. Expression of HLA-DR could be detected also in HL60 cells (33%) after HIV-1 infection. In H9 cells, CD4 was reduced from 60 to 30% after HIV-1 infection, whereas HLA-DR and CD25/IL-2 receptor expression increased from 16 to 90% and from 0 to 50%, respectively. CD4 was reduced from 70 to 0% from Jurkat cells after HIV-1 infection, whereas expression of CR2 was only slightly diminished from 8 to 4%. Expression of CR1 and HLA-DR was slightly increased in these cells (1 to 3%).(ABSTRACT TRUNCATED AT 250 WORDS)
Mosquito Control in the Aquatic Environment with Monomolecular Organic Surface Films. (1976)

The lifestyle of immature forms of the mosquito in water is highly dependent upon the properties of the air-water interface. Nonionic monomolecular organic films, which reduce surface tension and increase the wettability of breathing structures, produced high cumulative mortalities and mortality rates in fourth-instar larvae of Anopheles quadrimaculatus. These results were demonstrated both in the laboratory and in field studies. Effective surface films were maintained for at least 24 h with an initial application of only 0.04 ml of film-forming liquid per square meter of water surface. Two of the compounds, isostearyl alcohol (2 oxyethylene groups) and sorbitan monooleate, were 100% effective against these larvae in the field, each experiment involving about 5,000 organisms. Although laboratory research indicated that larvae of Aedes aegypti were not killed by the surface films studied, their development rate was greatly retarded. Three of the surface films caused 100% cumulative mortalities to pupae and emerging adults of this species. The mechanisms by which the film-induced surface affects the life cycle of the mosquito are discussed. Optimum properties of film-forming materials for practical mosquito-control applications are itemized and related to chemical structural considerations. The applicability and limitations of this approach to mosquito control are reviewed. (Author)
Traumatic Events and Posttraumatic Stress Disorder in an Urban Population of Young Adults (1991)

To ascertain the prevalence of posttraumatic stress disorder (PTSD) and risk factors associated with it, we studied a random sample of 1007 young adults from a large health maintenance organization in the Detroit, Mich, area. The lifetime prevalence of exposure to traumatic events was 39.1%. The rate of PTSD in those who were exposed was 23.6%, yielding a lifetime prevalence in the sample of 9.2%. Persons with PTSD were at increased risk for other psychiatric disorders; PTSD had stronger associations with anxiety and affective disorders than with substance abuse or dependence. Risk factors for exposure to traumatic events included low education, male sex, early conduct problems, extraversion, and family history of psychiatric disorder or substance problems. Risk factors for PTSD following exposure included early separation from parents, neuroticism, preexisting anxiety or depression, and family history of anxiety. Life-style differences associated with differential exposure to situations that have a high risk for traumatic events and personal predispositions to the PTSD effects of traumatic events might be responsible for a substantial part of PTSD in this population.
Rapid Immobilization of Enzymes onto Solid Supports by Ultrasound Waves (2011)

Herein, we describe a non-conventional method for immobilization of enzymes onto different solid surfaces using ultrasound as a source of energy. When horseradish peroxidase (HRP) was taken on the surface of an activated support and allowed to float on a sonicator bath operating at a frequency of 40 KHz, it readily started binding itself to the surface. Maximum binding was observed in 10 min whereas a control experiment carried out similarly without ultrasound waves showed insignificant immobilization. Ultrasound wave-mediated immobilization is rapid and reproducible and is better suitable for versatile applications in different fields, including fabrication of enzyme-based biosensors or bioreactors.
The study of effective factors on the success of suggestion system from the viewpoint of Ahvaz’s Department of Education Experts (2013)

One of staffs’ participation methods is the suggestion system based on which organization staffs can recommend for every case or subject and they will be rewarded if their suggestions guarantee fee reduction, better work, satisfaction increase, or accomplishment ease and speed, and other advantages of this kind, and approved. Last decades have witnessed staffs’ participation in running organizations to achieve the goals and success. Suggestions system based on cumulative thoughts attempts to utilize all staffs’ innovations, opinions and viewpoints for widespread organizational development. The Ahvaz department of education puts suggestion system implementation on its agenda in 2002. But, inspite of all wide propaganda it has not reached its goal, receiving one suggestion from each staff, during these years. The purpose of this study is to study the effective factors on suggestions system success from the viewpoints of Ahvaz’s department of education experts. Data analysis of questionnaires revealed that environmental factors play a role in suggestions system success and it was ranked as the first with the mean 3.7 regarding other factors. Management factors were ranked as the second (M: 3.6), personal factors as the third (M:3.6) and organizational factors as the forth with the mean of 3.4. The current study hopes for the would -be success in the suggestions system. Recognizing those factors is of great importance to managers and staffs in achieving the organizational goals. The educational department staffs know the organizational betterment as one of their duties based on the effective factors on suggestions system success due to the results of the current study. It is recommended that the senior manager should support the suggestion system more strictly, a full-time, sympathetic, and active teacher should be chosen for recruitment center, the staffs’ suggestions should be considered as soon as possible and the rewards should be paid, the suggestions executives ought to be encouraged and rewarded as well.
Continuous manufacturing of aligned carbon nanotube films (2010)

nanotubes, chemical vapor deposition, rolling, printing, nanomanufacturing We present a continuous manufacturing process for low-cost and scalable production of vertically aligned carbon nanotube (CNT) forests, along with continuous rolling of the CNTs to create horizontally aligned (HA) CNT ribbons and sheets. These methods are capable of producing uniform films over wafer-scale dimensions and beyond, and the CNTs can be patterned by lithography and plasma etching to achieve feature dimensions down to the micron scale. In this paper, we describe the design, manufacturing and related process physics of (1) a chemical vapor deposition (CVD) chamber apparatus for continuous CNT forest growth on a re-circulating catalyst-coated substrate; and (2) a mechanical rolling machine for CNT densification and transfer printing. Together, these innovations enable integration of CNT high quality and ordered CNTs growth with electronics and composites manufacturing on arbitrary substrates, including flexible plastics, fiber laminates, and metal foils.