gebhart/patrepeval huggingface dataset:
Cloning and Characterization of Low-Molecular-Weight Glutenin Subunit Alleles from Chinese Wheat Landraces (<i>Triticum aestivum</i>L.) (2014)

Low-molecular-weight glutenin subunits (LMW-GS) are of great importance in processing quality and participate in the formation of polymers in wheat. In this study, eight new LMW-GS alleles were isolated from Chinese wheat landraces (Triticum aestivum L.) and designated as Glu-A3-1a, Glu-A3-1b, Glu-B3-1a, Glu-B3-1b, Glu-B3-1c, Glu-D3-1a, Glu-D3-1b, and Glu-D3-1c, which were located at the Glu-A3, Glu-B3, and Glu-D3 loci, respectively. Based on the proteins encoded, the number of deduced amino acids of Glu-B3 alleles was approximately 50 more than those of Glu-A3 and Glu-D3 alleles. The first cysteine of Glu-A3 and Glu-D3 alleles was located at the N-terminal domain, while that of Glu-B3 alleles was found in the repetitive domain, which may lead to the different functioning in forming disulfide bonds. All the eight genes were LMW-m types and the new allele of Glu-B3-1a which had nine cysteine residues may be the desirable LMW-GS gene for improving bread-making quality.
Secure Information Processing with Privacy Assurance - standard based design and development for biometric applications (2010)

This paper presents the design and development of a technique referred to as SIPPA - Secure Information Processing with Privacy Assurance - for biometric data reconstruction. SIPPA enables a client/server model with the following two properties: (1) the client party can compare the similarity between his/her sample data with the source data on the server side — without each party revealing his/her data to another, nor to a third party. If the sample data is “sufficiently similar” to the source data, the client can reconstruct the source data by using only the sample data and some helper data with negligible overhead provided by the server. The main contributions of this paper are: (1) algorithmic steps of SIPPA and its relationship to privacy homomorphism, (2) a parallel SIPPA architecture, and (3) the realization of parallel SIPPA as a service component for BioAPI 2.0 framework using Java RMI technology. To demonstrate its potential application, we apply SIPPA to the reconstruction of biometric data, and more specifically, biometric face images represented in terms of linearized vectors.
Milliwatt-level output power in the sub-terahertz range generated by photomixing in a GaAs photoconductor (2011)

It is shown from accurate on-wafer measurement that continuous wave output powers of 1.2 mW at 50 GHz and 0.35 mW at 305 GHz can be generated by photomixing in a low temperature grown GaAs photoconductor using a metallic mirror Fabry-Pérot cavity. The output power is improved by a factor of about 100 as compared to the previous works on GaAs photomixers. A satisfactory agreement between the theory and the experiment is obtained in considering both the contribution of the holes and the electrons to the total photocurrent.
Gossiping with Multiple Messages (2007)

This paper investigates the dissemination of multiple pieces of information in large networks where users contact each other in a random uncoordinated manner, and users upload one piece per unit time. The underlying motivation is the design and analysis of piece selection protocols for peer-to-peer networks which disseminate files by dividing them into pieces. We first investigate one-sided protocols, where piece selection is based on the states of either the transmitter or the receiver. We show that any such protocol relying only on pushes, or alternatively only on pulls, will be inefficient in disseminating all pieces to all users. We propose a hybrid one-sided piece selection protocol -INTERLEAVE -and show that by using both pushes and pulls it disseminates k pieces from a single source to n users in 10(k + log n) time, while obeying the constraint that each user can upload at most one piece in one unit of time. An optimal, unrealistic centralized protocol would take k + log <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> n time in this setting. Moreover, efficient dissemination is also possible if the source implements forward erasure coding, and users push the latest-released coded pieces (but do not pull). We also investigate two-sided protocols where piece selection is based on the states of both the trasmitter and the receiver. We show that it is possible to disseminate n pieces to n users in + O(log n) time, starting from an initial state where each user has a unique piece.
Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in <i>Arabidopsis thaliana</i> (2007)

RecQ helicases are involved in the processing of DNA structures arising during replication, recombination, and repair throughout all kingdoms of life. Mutations of different RecQ homologues are responsible for severe human diseases, such as Blooms (BLM) or Werner (WRN) syndrome. The loss of RecQ function is often accompanied by hyperrecombination caused by a lack of crossover suppression. In the Arabidopsis genome seven different RecQ genes are present. Two of them (AtRECQ4A and 4B) arose because of a recent duplication and are still nearly 70% identical on a protein level. Knockout of these genes leads to antagonistic phenotypes: the RECQ4A mutant shows sensitivity to DNA-damaging agents, enhanced homologous recombination (HR) and lethality in a mus81 background. Moreover, mutation of RECQ4A partially suppresses the lethal phenotype of an AtTOP3alpha mutant, a phenomenon that had previously been demonstrated for RecQ homologues of unicellular eukaryotes only. Together, these facts strongly suggest that in plants RECQ4A is functionally equivalent to SGS1 of Saccharomyces cerevisiae and the mammalian BLM protein. In stark contrast, mutants of the closely related RECQ4B are not mutagen-sensitive, not viable in a mus81 background, and unable to suppress the induced lethality caused by loss of TOP3alpha. Moreover, they are strongly impaired in HR. Thus, AtRECQ4B is specifically required to promote but not to suppress crossovers, a role in which it differs from all eukaryotic RecQ homologues known.
Transgenic soybean overexpressing <i>Gm<scp>SAMT</scp>1</i> exhibits resistance to multiple‐<scp>HG</scp> types of soybean cyst nematode <i>Heterodera glycines</i> (2016)

Soybean (Glycine max (L.) Merr.) salicylic acid methyl transferase (GmSAMT1) catalyses the conversion of salicylic acid to methyl salicylate. Prior results showed that when GmSAMT1 was overexpressed in transgenic soybean hairy roots, resistance is conferred against soybean cyst nematode (SCN), Heterodera glycines Ichinohe. In this study, we produced transgenic soybean overexpressing GmSAMT1 and characterized their response to various SCN races. Transgenic plants conferred a significant reduction in the development of SCN HG type 1.2.5.7 (race 2), HG type 0 (race 3) and HG type 2.5.7 (race 5). Among transgenic lines, GmSAMT1 expression in roots was positively associated with SCN resistance. In some transgenic lines, there was a significant decrease in salicylic acid titer relative to control plants. No significant seed yield differences were observed between transgenics and control soybean plants grown in one greenhouse with 22 °C day/night temperature, whereas transgenic soybean had higher yield than controls grown a warmer greenhouse (27 °C day/23 °C night) temperature. In a 1-year field experiment in Knoxville, TN, there was no significant difference in seed yield between the transgenic and nontransgenic soybean under conditions with negligible SCN infection. We hypothesize that GmSAMT1 expression affects salicylic acid biosynthesis, which, in turn, attenuates SCN development, without negative consequences to soybean yield or other morphological traits. Thus, we conclude that GmSAMT1 overexpression confers broad resistance to multiple SCN races, which would be potentially applicable to commercial production.
Mechanism of glucoregulatory responses to stress and their deficiency in diabetes. (1991)

During exercise, increased energy demands are met by increased glucose production that occurs simultaneously with the increased glucose uptake. We had previously observed that, during exercise, metabolic clearance rate of glucose (MCR) increases markedly in normal, but only marginally in poorly controlled diabetic dogs. We wished to determine (i) whether in a more general model of stress matched increases in rate of appearance of glucose and MCR also occur, or if MCR is suppressed, as during catecholamine infusion; and (ii) whether diabetes affects stress-induced changes in rate of glucose appearance and MCR. Therefore, we injected carbachol (27 nmol/50 microliters), an analog of acetylcholine, intracerebroventricularly in seven conscious dogs before and after induction of alloxan diabetes. In normal dogs, plasma epinephrine and cortisol increased 4- to 5-fold, whereas norepinephrine and glucagon doubled. Plasma insulin, however, remained unchanged. Tracer-determined hepatic glucose production increased rapidly, but transiently, by 2.5-fold. This increment can be fully explained by the observed increments in the counterregulatory hormones. Surprisingly, however, MCR also promptly increased, and therefore, plasma glucose changed only marginally. After induction of diabetes, the animals were given intracerebroventricular carbachol while plasma glucose was maintained at moderate hyperglycemia (9.0 +/- 0.4 mM). Increments in counterregulatory hormones were similar to those seen in normal dogs, except for exaggerated norepinephrine release. Peripheral insulin levels were higher in diabetic than in normal dogs; however, MCR was markedly reduced and the lipolytic response to stress increased, indicating insulin resistance. Interestingly, the hyperglycemic response to stress was 6-fold greater in diabetic than normal animals, relating mainly to the failure of MCR to rise. Plasma lactate increased equivalently in diabetic and normal animals despite suppression of MCR in the diabetics, indicating either greater muscle glycogenolysis and/or impairment in glucose oxidation. We conclude that in this stress model MCR increases as in exercise in normal but not in diabetic dogs. We speculate that glucose uptake in stress could be mediated through an insulin-dependent neural mechanism.
A 622 Mbps ATM switch access LSI with multicast capable per-VC queueing architecture (2003)

We have developed a switch access LSI with multiple ports, SAM, which functions as an interface to an ATM switch fabric. It constitutes a switch chipset with another two chips, and it can be used to construct a non-blocking ATM switch. SAM has a unique queueing architecture to achieve remarkable features that include shaping port, per-VC queueing, and flexible multicast. Additionally, SAM provides various ATM layer functions required in most ATM switch systems, i.e., ER mode and EFCI mode of ABR switch behavior with BECN mechanism, frame discarding, EFCI marking, CLP selective discarding, UPC cell tagging and discarding, and automatic OAM cell processing.
IFN-αβ Promote Priming of Antigen-Specific CD8+ and CD4+ T Lymphocytes by Immunostimulatory DNA-Based Vaccines (2002)

Immunostimulatory sequence (ISS) DNA containing unmethylated CpG dinucleotides stimulate NK and APC to secrete proinflammatory cytokines, including IFN-alphabeta and -gamma, TNF-alpha, and IL-6 and -12, and to express costimulatory surface molecules such as CD40, B7-1, and B7-2. Although ISS DNA has little direct effect on T cells by these criteria, immunization of wild-type mice with ISS DNA and OVA results in Ag-specific CTL and Th1-type T helper activity. This investigation examines the mechanisms by which ISS DNA primes CD8(+) and CD4(+) lymphocyte activities. In this report we demonstrate that ISS DNA regulates the expression of costimulatory molecules and TAP via a novel autocrine or paracrine IFN-alphabeta pathway. Coordinated regulation of B7 costimulation and TAP-dependent cross-presentation results in priming of Ag-specific CD8(+) CTL, whereas CD40, B7, and IL-12 costimulation is required for priming of CD4(+) Th cells by ISS-based vaccines.
Injury‐induced spinal motor neuron apoptosis is preceded by DNA single‐strand breaks and is p53‐ and Bax‐dependent (2002)

The mechanisms of injury-induced apoptosis of neurons within the spinal cord are not understood. We used a model of peripheral nerve-spinal cord injury in the rat and mouse to induce motor neuron degeneration. In this animal model, unilateral avulsion of the sciatic nerve causes apoptosis of motor neurons. We tested the hypothesis that p53 and Bax regulate this neuronal apoptosis, and that DNA damage is an early upstream signal. Adult mice and rats received unilateral avulsions causing lumbar motor neurons to achieve endstage apoptosis at 7-14 days postlesion. This motor neuron apoptosis is blocked in bax(-/-) and p53(-/-) mice. Single-cell gel electrophoresis (comet assay), immunocytochemistry, and quantitative immunogold electron microscopy were used to measure molecular changes in motor neurons during the progression of apoptosis. Injured motor neurons accumulate single-strand breaks in DNA by 5 days. p53 accumulates in nuclei of motor neurons destined to undergo apoptosis. p53 is functionally activated by 4-5 days postlesion, as revealed by immunodetection of phosphorylated p53. Preapoptotically, Bax translocates to mitochondria, cytochrome c accumulates in the cytoplasm, and caspase-3 is activated. These results demonstrate that motor neuron apoptosis in the adult spinal cord is controlled by upstream mechanisms involving DNA damage and activation of p53 and downstream mechanisms involving upregulated Bax and cytochrome c and their translocation, accumulation of mitochondria, and activation of caspase-3. We conclude that adult motor neuron death after nerve avulsion is DNA damage-induced, p53- and Bax-dependent apoptosis.
Characterization of iron-doped lithium niobate for holographic storage applications (1976)

A detailed study of eight systematically chosen Fe : LiNbO3 crystals is presented. Correlation between the photorefractive sensitivity and various chemical properties of Fe : LiNbO3 is investigated in order to ascertain optimum performance of the crystals in holographic storage and display applications. Concentrations of Fe2+ and Fe3+ ions have been determined from optical and EPR spectra, while impurities have been detected from x-ray-emission and infrared spectra. Particular emphasis is placed on investigating the dependence on Fe2+ and Fe3+ ion concentrations of the photorefractive sensitivity. The photorefractive sensitivity is shown to depend primarily on the concentration of Fe2+ ions in Fe : LiNbO3. This fact seems to suggest that Fe2+ ions are the impurity centers responsible for the photorefractive effect in Fe : LiNbO3. Spectral dependence of the photorefractive sensitivity and its modification due to oxygen annealing are also reported. Our results indicate that an unannealed Fe : LiNbO3 crystal containing 0.05 mol% Fe with 20–25% of the ions in the Fe2+ state and the remainder in the Fe3+ state possesses the most favorable photorefractive sensitivity.
Biosynthesis of the O-glycosidically linked oligosaccharide chains of fetuin. Indications for an alpha-N-acetylgalactosaminide alpha 2 leads to 6 sialyltransferase with a narrow acceptor specificity in fetal calf liver. (1983)

Fetal calf liver microsomes were found to be capable of sialylating 14C-galactosylated ovine submaxillary asialomucin. The main oligosaccharide product chain could be obtained by beta-elimination under reductive conditions and was identified as NeuAc alpha 2 leads to 3Gal beta 1 leads to 3GalNAcol (where GalNAcol represents N-acetylgalactosaminitol) by means of high performance liquid chromatography (HPLC) analysis and methylation. The branched trisaccharide Gal beta 1 leads to 3(NeuAc alpha 2 leads to 6)-GalNAcol and the disaccharide NeuAc alpha 2 leads to 6GalNAcol were not formed. Very similar results were obtained when asialofetuin and antifreeze glycoprotein were used as an acceptor. When 3H-sialylated antifreeze glycoprotein ([3H]NeuAc alpha 2 leads to 3Gal beta 1 leads to 3GalNAc-protein) was incubated with fetal calf liver microsomes and CMP-[14C]NeuAc, a reduced tetrasaccharide could be isolated. The structure of this product chain appeared to be [3H]NeuAc alpha 2 leads to 3Gal beta 1 leads to 3([14C]NeuAc alpha 2 leads to 6)GalNAcol, as established by means of HPLC analysis, specific enzymatic degradation with Newcastle disease virus neuraminidase, and periodate oxidation. These data indicate that fetal calf liver contains two sialyltransferases involved in the biosynthesis of the O-linked bisialotetrasaccharide chain. The first enzyme is a beta-galactoside alpha 2 leads to 3 sialyltransferase which converts Gal beta 1 leads to 3 GalNAc chains to the substrate for the second enzyme, a (NeuAc alpha 2 leads to 3Gal beta 1 leads to 3)GalNAc-protein alpha 2 leads to 6 sialyltransferase. The latter enzyme does not sialylate GalNAc or Gal beta 1 leads to 3GalNAc units but is capable of transferring sialic acid to C-6 of GalNAc in NeuAc alpha 2 leads to 3Gal beta 1 leads to 3GalNAc trisaccharide side chains, thereby dictating a strictly ordered sequence of sialylation of the Gal beta 1 leads to 3 GalNAc units in fetal calf liver.
A benthic paleohabitat for Praepararotalia gen. nov. and Antarcticella Loeblich and Tappan (1998)

Globorotalia inconspicua Howe, G. aculeata Jenkins, G. Perclara Loeblich and Tappan (senior synonym of G. reissi Loeblich and Tappan), Globigerina pauciloculata Jenkins, and Candeina antarctica Leckie and Webb are Cenozoic species interpreted to have been adapted to a planktic habitat. Their restriction, however, to shallow marine or marginal marine paleoenvironments suggests that they were benthic species. These taxa are associated with reduced planktic foraminiferal diversity, a low P/B (planktic/benthic) ratio, and an inner shelf benthic foraminiferal biofacies. A new genus, Praepararotalia, is erected for several species interpreted to be phylogenetically related to the benthic genus Pararotalia. Praepararotalia cretacea (new species), which is described from the Maastrichtian Navesink Formation in New Jersey, gave rise to the early Paleocene species Praepararotalia perclara. In addition, stable isotopic (delta 18 O and delta 13 C) signatures of all praepararotaliid species in this study cluster closer to benthic foraminiferal signatures and are distinct from normal marine planktic taxa from the Cretaceous and the Paleocene. A benthic paleohabitat is suggested for the Danian species Antarcticella pauciloculata (Jenkins) because of its dominant occurrence in shallow facies of marginal basins in the southern high latitudes. The species may be phylogenetically linked to P. cretacea n. sp. and is apparently the stem taxon of a Southern Ocean Paleogene evolutionary lineage that includes A. cecionii (Canon and Ernst), A. zeocenica (Hornibrook and Jenkins), and A. antarctica (Leckie and Webb).
Redox and ion-pairing thermodynamics in self-assembled monolayers (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRedox and ion-pairing thermodynamics in self-assembled monolayersGary K. Rowe and Stephen E. CreagerCite this: Langmuir 1991, 7, 10, 2307–2312Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://pubs.acs.org/doi/10.1021/la00058a055https://doi.org/10.1021/la00058a055research-articleACS PublicationsRequest reuse permissionsArticle Views1629Altmetric-Citations358LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A cost effective 32nm high-K/ metal gate CMOS technology for low power applications with single-metal/gate-first process (2008)

For the first time, we have demonstrated a 32nm high-k/metal gate (HK-MG) low power CMOS platform technology with low standby leakage transistors and functional high-density SRAM with a cell size of 0.157 μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . Record NMOS/PMOS drive currents of 1000/575 μA/μm, respectively, have been achieved at 1 nA/μm off-current and 1.1V V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</inf> with a low cost process. With this high performance transistor, V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</inf> can be further scaled to 1.0V for active power reduction. Through aggressive EOT scaling and band-edge work-function metal gate stacks, appropriate Vts and superior short channel control has been achieved for both NMOS and PMOS at L <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">gate</inf> =30nm. Compared to SiON-Poly, 30% RO delay reduction has been demonstrated with HK-MG devices. 40% Vt mismatch reduction has been shown with the Tinv scaling. Furthermore, it has been shown that the 1/f noise and transistor reliability exceed the technology requirements.
Nanostructured Potential of Optical Trapping Using a Plasmonic Nanoblock Pair (2013)

We performed two-dimensional mapping of optical trapping potentials experienced by a 100 nm dielectric particle above a plasmon-resonant gold nanoblock pair with a gap of several nanometers. Our results demonstrate that the potentials have nanoscale spatial structures that reflect the near-field landscape of the nanoblock pair. When an incident polarization parallel to the pair axis is rotated by 90°, a single potential well turns into multiple potential wells separated by a distance smaller than the diffraction limit; this is associated with super-resolution optical trapping. In addition, we show that the trap stiffness can be enhanced by approximately 3 orders of magnitude compared to that with conventional far-field trapping.