gebhart/patrepeval huggingface dataset:
Spatial features of calcium‐regulated gene expression (1997)

A key characteristic of an animal's nervous system is that it can respond to brief environmental stimuli with lasting changes in its structure and function. These changes are triggered by specific patterns of neuronal electrical activity and are manifested as changes in the strength and patterns of synaptic connectivity between activated neurons. The biochemical mechanisms that control these changes are unclear, but cytoplasmic rises in Ca2+ levels may play a critical role, especially in regulating neuronal gene expression for making activity-induced synaptic changes permanent. Recently, two reports have explored the spatial features by which activity-induced rises in Ca2+ levels activate transcription factors and gene expression. The reports suggest that Ca2+ influx acts both locally at the synapse and distantly within the nucleus to regulate transcription factors and gene expression. The results also show that regulatory elements within genes can respond differentially, depending on spatial differences in intracellular Ca2+ rises. These reports suggest new spatial mechanisms by which Ca(2+)-dependent gene expression could contribute to activity-dependent synaptic changes.
Automatic Melanoma Detection Using Multi- Stage Neural Networks (2014)

Skin cancer accounts for more than half of all cancers detected in USA every year. Melanoma is less common, but more aggressive and hence more dangerous than the other types of skin cancers. Even though there has been extensive research in the past 20 years on automatic melanoma detection from skin lesion images, most of the dermatologists still do not have access to this technology. In this paper, a novel system is proposed. The system uses enhanced image processing to segment the images without manual intervention. From the segmented image, it extracts a comprehensive set of features using new and improved techniques. The features were fed automatically to a multistage neural network classifier which achieved greater than 97% sensitivity and greater than 93% specificity. The trained system was tested with lesion images found online and it was able to achieve similar sensitivity. Finally, a new approach that will simplify the entire diagnosis process is discussed. This approach uses Dermlite® DL1 dermatoscope that can be attached to the iPhone. After taking the lesion image with a dermatoscope attached iPhone, the physician gets the diagnosis with a few simple clicks. This system could have widespread ramifications on melanoma diagnosis. It achieves higher sensitivity than previous research and provides an easy to use iPhone based app to detect melanoma in early stages without the need for biopsy.
A semi-autonomous security robot employing telepresence (1998)

article A semi-autonomous security robot employing telepresence Share on Authors: Takashi Nishiyama Center of Matsushita Electric Works, Ltd., Osaka, Japan Center of Matsushita Electric Works, Ltd., Osaka, JapanView Profile , Junji Nomura Center of Matsushita Electric Works, Ltd., Osaka, Japan Center of Matsushita Electric Works, Ltd., Osaka, JapanView Profile , Ryoji Nakajima Center of Matsushita Electric Works, Ltd., Osaka, Japan Center of Matsushita Electric Works, Ltd., Osaka, JapanView Profile , Tetsuji Miyanoh Center of Matsushita Electric Works, Ltd., Osaka, Japan Center of Matsushita Electric Works, Ltd., Osaka, JapanView Profile Authors Info & Claims Communications of the ACMVolume 41Issue 5esMay 1998 pp 198–205https://doi.org/10.1145/276404.276411Published:01 May 1998 1citation553DownloadsMetricsTotal Citations1Total Downloads553Last 12 Months7Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
TSMC turnkey data mart (2004)

TSMC turnkey data mart is the collection of databases, designed to help managers make strategic decisions about their business. It focuses on operation management department and aid their managers and planners to get useful information from the system. The data mart creation service moves data from a variety of sources such as ERP system, B2B transaction system, Supply Chain Management system, EDA system and MES databases to build the Turnkey data mart. The data mart creation is used by IT administrators to deliver star or snowflake schemas, which present multi-dimensional models of data warehouses. The dimensional model contains the same information as found in a complex Entity Relationship model, but it makes the information easier to understand, facilitates querying and is resilient to change.
Indocyanine green fluorescence angiography during laparoscopic rectal surgery (2017)

Advances in medical equipment and surgical techniques have enabled surgeons to offer patients better oncological and clinical outcomes after colorectal resections.
P53 Gene Alterations in Human Prostate Carcinoma (1993)

Alterations of the p53 gene are among the most frequent genetic lesions in a variety of human malignancies. Their role in prostate cancer is, however, unclear. We have analyzed 10 primary and two metastatic human prostate carcinomas as well as 3 prostate cancer cell lines for mutations of the p53-gene. Using single strand conformational polymorphism analysis (SSCP) and direct sequencing of the polymerase chain reaction (PCR) products, p53 mutations were detected in 1 of 10 primary prostate cancers. By contrast, 1 of 2 metastatic tumors and all 3 prostate cancer cell lines (derived from metastases) were found to contain a mutant p53 gene. Thus, our data suggest that alterations of the p53 gene at the mutational "hot spots" appear to occur infrequently in primary human prostate cancer, but may emerge in later stages of tumor progression. Furthermore, we confirm that loss of heterozygosity at a locus telomeric to p53, but not including p53, is associated with metastatic progression in 1 case.
Effectively Tunable Dispersion Compensation Based on Chirped Fiber Bragg Gratings Without Central Wavelength Shift (2004)

A systematic method of tunable dispersion compensation based on chirped fiber Bragg gratings (CFBGs) without a center wavelength shift will be proposed. The specially designed mechanical rotator can flexibly control the chirping ratio along the fiber gratings and consequently the group delay. The group delay can be linearly controllable since the proposed method can induce the linear strain gradient with the rotation angle change. The dispersion value can be effectively controlled in the range from -495.5 to -1406.0 ps/nm corresponding to the rotation angle. The resonant wavelength shift of CFBG is less than 0.03 nm over the dispersion tuning range. The theoretical analysis of the tuning mechanism based on the proposed method will also be discussed.
A new concept of a low-frequency underwater sound source (1994)

A new concept of a low-frequency (&lt;1000-Hz) underwater sound source has been developed and tested. The oscillation of a rigid body and a means for converting the dipole oscillation of the body to monopole radiation are used in this source. The source can be powered with electric or linear motors or hydrodynamic exciters that convert tow or flow to vibration. To prove the concept, a small version of the electric motor powered source has been built and successfully tested. To extend the bandwidth of the source, the variable resonance frequency and multiresonances of the device are discussed. A gas spring with a frequency-dependent stiffness is employed for the multifrequency resonant source design. The source promises to be reliable, inexpensive, highly efficient, and powerful.
Semantic segmentation with heterogeneous sensor coverages (2014)

We propose a new approach to semantic parsing, which can seamlessly integrate evidence from multiple sensors with overlapping but possibly different fields of view (FOV), account for missing data and predict semantic labels over the spatial union of sensors coverages. The existing approaches typically carry out semantic segmentation using only one modality, incorrectly interpolate measurements of other modalities or at best assign semantic labels only to the spatial intersection of coverages of different sensors. In this work we remedy these problems by proposing an effective and efficient strategy for inducing the graph structure of Conditional Random Field used for inference and a novel method for computing the sensor domain dependent potentials. We focus on RGB cameras and 3D data from lasers or depth sensors. The proposed approach achieves superior performance, compared to state of the art and obtains labels for the union of spatial coverages of both sensors, while effectively using appearance or 3D cues when they are available. The efficiency of the approach is amenable to realtime implementation. We quantitatively validate our proposal in two publicly available datasets from indoors and outdoors real environments. The obtained semantic understanding of the acquired sensory information can enable higher level tasks for autonomous mobile robots and facilitate semantic mapping of the environments.
Effects of target thickness on spectral characteristics of x-ray flux from the laser-produced plasmas (2004)

A detailed numerical simulation study of spectral characteristics of the x-ray flux from gold foil targets of different thickness irradiated by a 1ns laser pulse with 1014W/cm2 intensity at 0.35μm wavelength using the one dimensional radiation hydrodynamic code MULTI is investigated using one dimensional radiation hydrodynamic code MULTI.This is very important in the diagnosis of the x-ray spectrum and the design of an x-ray source.
Fabrication of a tissue-equivalent torso phantom for intercalibration of in-vivo transuranic-nuclide counting facilities (1978)

A tissue-equivalent human-torso phantom has been constructed for calibration of the counting systems used for in-vivo measurement of transuranic nuclides. The phantom contains a human male rib cage, removable model organs, and includes tissue-equivalent chest plates that can be placed over the torso to simulate people with a wide range of statures. The organs included are lungs, heart, liver, kidneys, spleen, and tracheo-bronchial lymph nodes. Polyurethane with different concentrations of calcium carbonate was used to simulate the linear photon-attenuation properties of various human tissues--lean muscle, adipose-muscle mixtures, and cartilage. Foamed polyurethane with calcium carbonate simulates lung tissue. Transuranic isotopes can be incorporated uniformly in the phantom's lungs and other polyurethane-based organs by dissolution of the nitrate form in acetone with lanthanum nitrate carrier. Organs have now been labelled with highly pure /sup 238/Pu, /sup 239/Pu, and /sup 241/Am for calibration measurements. This phantom is the first of three that will be used in a U.S. Department of Energy program of intercomparisons involving more than ten laboratories. The results of the intercomparison will allow participating laboratories to prepare sets of transmission curves that can be used to predict the performance of their counting systems for a wide range of subject builds and organ depositions. The intercomparison will also provide valuable information on the relative performance of a variety of detector systems and counting techniques.
Emergency endovascular repair for traumatic injury of the inferior vena cava☆ (2005)

Conventional open repair of the traumatic injuries of the inferior vena cava still represents a surgical challenge, since it carries high morbidity and mortality rates close to 100% in emergency setting. Surgical techniques required the total mobilization of the liver in the former case and the anatomic exposure of the aorto-iliac bifurcation in the latter. We report a case of uncontrolled hemorrhage from the inferior vena cava, managed by endovascular technique. A 65-year-old woman underwent endovascular stent-grafting for traumatic injury of the inferior vena cava. We performed the endovascular approach as we similarly did for aortic repair using a simple groin access through the common femoral vein; no additional dissection of the inferior vena cava or adjacent structures was needed using endovascular approach, thus avoiding additional operative trauma, and time with the stent-graft procedure was 9 min. Inferior vena cava stent-grafting without laparotomy and retroperitoneal dissection is feasible and could be a very attractive alternative to open surgery for rupture of the vena cava.
The Attorney-Client Privilege and the Work Product Immunity Doctrine for the Corporate Client (1986)

Corporate counsel are charged with the task of protecting information relayed to them or compiled at the behest of a client. This article examines problems encountered by corporate counsel attempting to invoke the attorney-client privilege or work product immunity doctrine to protect information. The author recommends that corporate counsel implement procedures designed to retain confidentiality and remain abreast of modifications in case law pertaining to attorney-client privilege and work product immunity. The confidentiality of corporate information is best preserved by adherence to an organized system of procedures for gathering information.
Using comsumer informedness as an information strategy (2014)

This article is intended to prepare the dermatology nurse to competently and confidently assist in the deep chemical peel and to manage the care of the patient effectively before, during, and after the procedure.
Medicine prices, availability, and affordability in Vietnam. (2009)

Objective: To assess the price, availability and affordability of a sample of medicines in Vietnam. Methods: Data on the price and availability of 42 medicines were collected using the standard World Health Organization/Health Action International (WHO/HAI) methodology in five geographical areas in Vietnam. The median price of these medicines was compared with the Management Science for Health international reference prices (IRPs), expressed as median price ratios. Affordability was measured as the number of days’ wages required for the lowest-paid unskilled government worker to purchase one course of therapy. Of the 42 medicines studied, 15 were chosen for international comparison, which were included in at least 80% of other country surveys using the WHO/HAI methodology. Results: Public sector availability of generic medicines was 33.6%. The median public procurement price was 1.82 times the IRPs for generics, but for some individual medicines it was less than half the IRP. The price to patients in public outlets was higher than in private pharmacies. Adjusted for Purchasing Power Parity in 2005, the lowest generic prices in private pharmacies were still 8.3 times the IRPs. Treatments were thus unaffordable for a large part of Vietnam’s population. Conclusions: Medicines in Vietnam were high in price, and low in both availability and affordability, especially in the public sector. To make public facilities a primary treatment option for the poor, Vietnam must reduce medicine prices in this sector by improving procurement efficiency, ensuring and promoting low-priced generics, and regulating reasonable mark-ups.
CTO recanalization by intraocclusion injection of contrast: The microchannel technique (2007)

Microinjection of contrast immediately distal to the proximal fibrous cap of a CTO may be an additional technique to facilitate recanalization of CTO.
Nano-silver paste with low roasting temperature (2006)

A kind of new silver paste with silver content about 50wt%, nano-silver paste, significantly different with normal silver paste in roasting temperature, was prepared using nano-silver powder, ethanol, n-butyl alcohol, n-hexyl alcohol and low polymer fibre. The nano-silver paste shows weight loss and volatilization with different levels on thermogravimetric (TG) analyzing curve. Field emission scanning electron microscope (FESEM) analysis indicates when roasting temperature is controlled at 200/spl deg/C, the surface of finished silver film has already been compact and smooth. And finished silver film has stronger adhesive with ceramic and mental substrates, while the adhesive is poor with slippery glass. The minimal square resistor of obtained silver film can reach 7.8m/spl Omega///spl square/.
A visual landmark framework for indoor mobile robot navigation (2003)

Presents vision functions needed on a mobile robot to deal with landmark-based navigation in buildings. Landmarks are planar, quadrangular surfaces, which must be distinguished from the background, typically a poster on a wall or a door-plate. In a first step, these landmarks are detected and their positions with respect to a global reference frame are learned; this learning step is supervised so that only the best landmarks are memorized, with an invariant representation based on a set of interest points. Then, when the robot looks for visible landmarks, the recognition procedure takes advantage of the partial Hausdorff distance to compare the landmark model and the detected quadrangles. The paper presents the landmark detection and recognition procedures, and discusses their performances.
[New bone formation by extracorporeal shock waves. Dependence of induction on energy flux density]. (2004)

The results of this study challenge the current view in the literature that the creation of cortical fractures and periosteal detachment are prerequisites for new bone formation mediated by extracorporeal shock waves.
News from the International Accounting Public Sector Board (IPSASB) (2015)

The publication of a Conceptual Framework from the International Public Sector Accounting Standards Board marks the start of 2015. The main intention of the new Conceptual Framework is all about self-improvement. At the beginning of a New Year many of us make New Year resolutions (some even keep them). For IPSASB the publication of the new Conceptual Framework is like issuing in a new era. The three most important New Year's resolutions they took reflect parallels between three of their most common goals and the impact of the framework.
Muscimol and Midazolam Do Not Potentiate Each Other's Effects on Sleep EEG in the Rat (1997)

The interaction of a gamma-aminobutyric acid-A (GABAA) receptor agonist and a benzodiazepine-type modulator of GABAA receptors on sleep was investigated. Low doses of muscimol (0.3 mg/kg) and the benzodiazepine midazolam (1.5 mg/kg) were administered alone and in combination, in random order, to eight rats. All injections were given intraperitoneally at light onset. Electroencephalogram (EEG) and electromyogram were recorded during the first 6 h post injection. Compared with vehicle, muscimol hardly affected the time spent in non-rapid eye movement sleep (non-REMS) and REMS, but significantly enhanced EEG activity in the frequency range between 2 and 6 Hz during non-REMS. Midazolam significantly increased the time spent in non-REMS, reduced EEG activity at frequencies < 12 Hz, and elevated EEG activity in most higher frequencies during this state. The combined administration of muscimol and midazolam affected non-REMS-specific EEG activity in an unexpected fashion: the effects were intermediate between those of muscimol and midazolam. These results indicate that muscimol and midazolam have dissimilar effects on EEG within non-REMS and demonstrate that midazolam does not augment but attenuates the muscimol-induced changes in sleep EEG. Our data are at variance with established mechanisms, according to which agonistic modulators would have similar effects and should potentiate the effects of GABAA agonists. The present data suggest that application of agonists and agonistic modulators of GABAA receptors causes differential net effects on sleep parameters.
The Cancer Family Syndrome Rare Cutaneous Phenotypic Linkage of Torre's Syndrome (1981)

Sebaceous neoplasia have been observed in members of four families exhibiting the cancer family syndrome (CFS). This disorder is characterized by adenocarcinomas, particularly involving the (proximal) colon, endometrium, and ovary; an excess of multiple primary cancer; early age of cancer onset; and autosomal dominant pattern of inheritance. Multiple adenomatous polyps are lacking in this disorder. In four patients from three of these cancer-prone kindreds, cutaneous lesions were accompanied by multiple visceral adenocarcinomas, fulfilling the criteria for Torre's syndrome, a disease that heretofore has not shown notable familial clustering characteristic of the CFS. Therefore, the coexistence of rare sebaceous neoplasia and visceral cancer in CFS supports the notion that some cases of Torre's syndrome may in fact represent the more full phenotypic expression of the gene responsible for the CFS.
High-Performance, Single-Layer Antireflective Optical Coatings Comprising Mesoporous Silica Nanoparticles (2011)

Mesoporous silica nanoparticles are used to fabricate antireflectance coatings on glass substrates. The combination of mesoporous silica nanoparticles in conjunction with a suitable binder material allows mechanically robust single layer coatings with a reflectance <0.1% to be produced by simple wet processing techniques. Further advantages of these films is that their structure results in broadband antireflective properties with a reflection minimum that can tuned between 400 nm and 1900 nm. The ratio of binder material to mesoporous nanoparticles allows control of the refractive index. In this report, we discuss how control of the structural properties of the coatings allows optimization of the optical properties.
Arthroscopic autologous condrocyte transplantation: technical note (2002)

We describe an arthroscopic surgical technique for tissue engineered cartilage grafting. A three-dimensional hyaluronic acid support is used for autologous chondrocyte culturing. The technique reduces morbidity of classic autologous implant and avoids open surgery and the use of a periosteal flap. The procedure includes the advantages of arthroscopic osteochondral grafting without donor site morbidity. With this technique is possible to reduce the patient morbidity, time and cost of surgery.
Integrating a Trust Framework with a Distributed Certificate Validation Scheme for MANETs (2006)

Many trust establishment solutions in mobile ad hoc networks (MANETs) rely on public key certificates. Therefore, they should be accompanied by an efficient mechanism for certificate revocation and validation. Ad hoc distributed OCSP for trust (ADOPT) is a lightweight, distributed, on-demand scheme based on cached OCSP responses, which provides certificate status information to the nodes of a MANET. In this paper we discuss the ADOPT scheme and issues on its deployment over MANETs. We present some possible threats to ADOPT and suggest the use of a trust assessment and establishment framework, named ad hoc trust framework (ATF), to support ADOPT's robustness and efficiency. ADOPT is deployed as a trust-aware application that provides feedback to ATF, which calculates the trustworthiness of the peer nodes' functions and helps ADOPT to improve its performance by rapidly locating valid certificate status information. Moreover, we introduce the TrustSpan algorithm to reduce the overhead that ATF produces, and the TrustPath algorithm to identify and use trusted routes for propagating sensitive information, such as third parties' accusations. Simulation results show that ATF adds limited overhead compared to its efficiency in detecting and isolating malicious and selfish nodes. ADOPT's reliability is increased, since it can rapidly locate a legitimate response by using information provided by ATF.