gebhart/patrepeval huggingface dataset:
Segmentation and 2D motion estimation by region fragments (2002)

A central problem in estimating multiple image motions is that 2-D motion estimation and region segmentation are mutually dependent. The authors present a new region description method for dealing with this mutual dependence problem. Segmentation and motion estimation are simultaneously performed by a clustering process based on color, motion, and pixel position. As a result of the clustering, an image is decomposed into region fragments. Each fragment is characterized by distribution parameters of color, pixel positions, and spatiotemporal intensity gradients. The image is described by the parameters of the region fragments; 2-D motion vectors for each fragment are obtained from the distribution parameters of the intensity gradients. By combining those features in the clustering process, regions are segmented more precisely, motion boundaries are not blurred, and the 2-D motions are obtained even in noisy areas. Experimental results are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone. (1990)

We have recently established that the human growth hormone-variant (hGH-V) gene is functional in vivo by documenting its expression in the placenta. We have subsequently generated transformed murine cell lines stably expressing the genes for normal pituitary growth hormone (hGH-N), hGH-V, and each of two chimeric genes generated by exon 3 exchanges, hGH-NV3 and hGH-VN3. In the present study, we utilize these cell lines as sources of hormone to characterize and compare the receptor binding profiles of hGH-N with hGH-V. hGH-V was found to displace 125I-ovine prolactin bound to rat liver microsomes (lactogen binding) and to displace 125I-hGH bound to rabbit liver microsomes (somatogen binding). Therefore, hGH-V would be predicted to display both somatogenic and lactogenic bioactivity, a dual specificity previously thought to be unique to hGH-N. The concentrations of hormone necessary to displace 50% (IC50) of the 125I-hGH from somatogen receptors and 125I-ovine prolactin from lactogen receptors was expressed as a ratio, IC50 somatogen: IC50 lactogen, for each hormone tested. A 7.4-fold difference in this ratio was observed for hGH-N compared to hGH-V, suggesting significantly greater selectivity by hGH-V in binding to the somatogen receptor. The intermediate binding ratios of the hGH-NV3 and hGH-VN3 chimeric proteins confirmed the distinct receptor binding profiles of the two parent hormones and served to identify three amino acids of potential importance in defining their respective receptor binding specificities.
Heteroepitaxial TiO<sub>2</sub>@W-doped VO<sub>2</sub> core/shell nanocrystal films: preparation, characterization, and application as bifunctional window coatings (2015)

We employed rutile TiO<sub>2</sub> nanoparticles (TiNPs) as cores for coating with vanadium sols to grow the VO<sub>2</sub>(M) heteroepitaxially as shells. Needle-like structures gradually appeared on the TiNP surfaces after a sintering process.
Real-Time Fleet Ship Monitoring System Using Satellite Broadband Communications and Google Earth (2009)

This work describes the development of a monitoring system for vessels from the Marine Technology Unit (UTM) of the Spanish Research Council (CSIC) and draws on the graph capabilities and the potential access to remote data that is offered by Google Earth and the new satellite data transmission capabilities installed on-board. Performance analysis is carried out at several critical points of the system, in terms of data processing and networking. This development is a product of a more ambitious acquisition project that deals with the modeling and acquisition of oceanographic data led by a working group at the UTM and the Universitat Politècnica de Catalunya. This system, with minor variations in implementation, can be adopted to monitor a greater number of mobile units while at the same time remain sufficiently flexible to be used as a didactic teaching tool for schools and universities
Spectrum-shaping method to improve spectral efficiency of OFDM systems (2003)

This paper proposes a spectrum-shaping filter for an OFDM signal. In the proposed method, the transmitted signal after multi-carrier modulation with the inverse Fourier transform is spectrally shaped by root-roll-off filters, and the received signal before Fourier transform is also shaped by the filters. An out-of-band emission level can be significantly reduced under the condition that the transmitted data can be perfectly recovered. The paper also describes an optimized impulse response of the filter to reduce the emission level. The resultant. filter has a new impulse response different from the root-roll-off filter. The effective roll-off factor of 0.1 and the emission level of less than -100 dB are obtained with the optimization when the number of filter taps is 201 at an over-sampling rate of 4. We calculate output power spectra with the proposed filter and a conventional raised cosine window in the time domain. The calculation results show that the signal bandwidth with the proposed method can be less than one third of the bandwidth with the conventional method at an emission level of -60 dB. Therefore, the proposed method can significantly improve the spectral efficiency of OFDM systems.
Association between OPRM1 gene polymorphisms and fentanyl sensitivity in patients undergoing painful cosmetic surgery (2009)

Individual differences in sensitivity to fentanyl, a widely used opioid analgesic, can hamper effective pain treatment. Still controversial is whether the single nucleotide polymorphisms (SNPs) of the human OPRM1 gene encoding the mu-opioid receptor influence the analgesic effects of opioids. We examined associations between fentanyl sensitivity and the two SNPs, A118G and IVS3+A8449G, in the human OPRM1 gene in 280 Japanese patients undergoing painful orofacial cosmetic surgery, including bone dissection. Regarding the A118G SNP in exon 1, in a cold pressor-induced pain test before surgery, less analgesic effects of fentanyl were shown in subjects carrying the minor G allele of the A118G SNP (median of difference between pain perception latencies before and after fentanyl injection [PPLpost-PPLpre]: 12s) compared with subjects not carrying this allele (PPLpost-PPLpre: 15s, p=0.046). Furthermore, the IVS3+A8449G SNP in intron 3, which represents a complete linkage disequilibrium block with more than 30 SNPs from intron 3 to the 3' untranslated region, was associated with 24-h postoperative fentanyl requirements. Subjects carrying the minor G allele of the IVS3+A8449G SNP required significantly less fentanyl for 24-h postoperative pain control (median: 1.5microg/kg) compared with subjects not carrying this allele (median: 2.5microg/kg, p=0.010). Although further validation is needed, the present findings shed light on the involvement of OPRM1 3' untranslated region polymorphisms in fentanyl sensitivity in addition to the A118G SNP and open new avenues for personalized pain treatment with fentanyl.
Biological activity, binding site and affinity of monoclonal antibodies to the fusion protein of respiratory syncytial virus (1994)

The neutralizing activity and fusion-inhibition activity per unit weight of immunoglobulin were determined for each of a panel of 20 monoclonal antibodies (MAbs) to the fusion (F) protein of respiratory syncytial (RS) virus. Neutralization did not correlate with fusion-inhibiting activity, suggesting that the F protein plays at least two independent, antibody-sensitive roles in viral infection. Antibodies with the highest biological activity against A2, a subgroup A strain of RS virus, neutralized a subgroup B strain (8/60) poorly, suggesting a degree of antigenic variation that may be important in human infection. All but one fusion-inhibiting MAb bound to protein blots and binding was mapped to two areas on overlapping F protein fragments. One MAb with relatively poor fusion-inhibiting activity bound only to fragments C-terminal of amino acid 384, the remainder bound only to fragments containing residues 253 to 289. MAbs directed to the latter site were heterogeneous in neutralizing activity, subgroup specificity and fusion-inhibiting activity. These variations between MAbs could not be accounted for by differences in their binding avidities. We suggest that this binding site is not the complete antibody epitope which probably includes conformation-dependent elements.
Lincomycin. VII. 4′-Depropyl-4′-ethoxylincomycins (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLincomycin. VII. 4′-Depropyl-4′-ethoxylincomycinsBarney J. MagerleinCite this: J. Med. Chem. 1967, 10, 6, 1161–1163Publication Date (Print):November 1, 1967Publication History Published online1 May 2002Published inissue 1 November 1967https://pubs.acs.org/doi/10.1021/jm00318a040https://doi.org/10.1021/jm00318a040research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Urban pixels (2009)

Urban environments are increasingly filled with digital display systems that are inflexible, flat, bounded, high-resolution, and unresponsive. In this paper, we explore the potential of physically instantiated pixels that enable flexible, reconfigurable, unbounded, low-resolution, and responsive urban displays. Urban Pixels are nodes in a wireless network of physical pixels for urban spaces. Each pixel unit includes a microcontroller, RF transceiver (433 MHz), LED module (ten bright, white LEDs), rechargeable Li-Ion battery pack, IR sensor and renewable energy source such as photo-voltaic cells. Two acrylic half-spheres (4-inch diameter) protect the components from the elements. No additional wiring is needed for communication and the units can be mounted individually to any surface. A small-scale prototype network of fifty Urban Pixels was displayed on a façade of Eden Court Theater in Inverness, Scotland from June 1 - June 7, 2008. The public was encouraged to change display patterns via SMS or to interact with individual units via flashlights. We observed and informally interviewed theater guests and passers-by interacting with the façade for several nights. Based on these results, we outline an exciting problem space for designing displays and lighting systems in cities.
Fecal-Coliform Bacteria in Extended-Aeration Plant Sludge (1998)

The concentration of fecal-coliform bacteria in sludge from extended-aeration plants was analyzed for compliance with new state and federal land application requirements. This study was initiated to determine if additional digestion would be necessary for plants to meet the new pathogen standards of less than 2 million CFU per gm of solids. Sludge was found to contain less than 2 million fecal coliform bacteria/gm of sludge as a result of a combination or aerobic digestion and/or long term storage.
Highly Practical Methodology for the Synthesis of<scp>d</scp>- and<scp>l</scp>-α-Amino Acids,<i>N</i>-Protected α-Amino Acids, and<i>N</i>-Methyl-α-amino Acids (1997)

Full details are provided for an exceedingly practical method to synthesize d- and l-α-amino acids, N-protected α-amino acids, and N-methyl-α-amino acids, employing as a key step the asymmetric alkylation of pseudoephedrine glycinamide (1) or pseudoephedrine sarcosinamide (2). Practical procedures for the synthesis of 1 and 2 from pseudoephedrine and glycine methyl ester or sarcosine methyl ester, respectively, are presented. Optimum protocols for the enolization and subsequent alkylation of 1 and 2 are described. Alkylation reactions of 1 and 2 are found to be quite efficient with a wide range of alkyl halide substrates, and the products are formed with high diastereoselectivity. The products of these alkylation reactions are hydrolyzed efficiently and with little to no racemization simply by heating in water or water−dioxane mixtures. This protocol provides an exceedingly practical method for the preparation of salt-free α-amino acids of high enantiomeric purity. Alternatively, the alkylation products may be hydrolyzed in high yield and with little to no racemization by heating with aqueous sodium hydroxide. The alkaline hydrolyzate can then be treated with an acylating reagent to provide directly highly enantiomerically enriched N-protected derivatives such as N-Boc and N-Fmoc. Key features necessary for the successful execution of these experimental procedures are identified.
Virtual Machine Migration Enabled Cloud Resource Management: A Challenging Task (2016)

Virtualization technology reduces cloud operational cost by increasing cloud resource utilization level. The incorporation of virtualization within cloud data centers can severely degrade cloud performance if not properly managed. Virtual machine (VM) migration is a method that assists cloud service providers to efficiently manage cloud resources while eliminating the need of human supervision. VM migration methodology migrates current-hosted workload from one server to another by either employing live or non-live migration pattern. In comparison to non-live migration, live migration does not suspend application services prior to VM migration process. VM migration enables cloud operators to achieve various resource management goals, such as, green computing, load balancing, fault management, and real time server maintenance. In this paper, we have thoroughly surveyed VM migration methods and applications. We have briefly discussed VM migration applications. Some open research issues have been highlighted to represent future challenges in this domain. A queue based migration model has been proposed and discussed to efficiently migrate VM memory pages.
An Evaluation of the Ability of the Probiotic Strain Lactobacillus rhamnosus GG to Eliminate the Gastrointestinal Carrier State of Vancomycin-resistant Enterococci in Colonized Children (2011)

LGG supplementation temporarily eliminates the VRE carrier state and increases gastrointestinal counts of Lactobacillus spp. in children versus placebo.
Inspection of PCBs by laser‐induced fluorescence (2002)

Examines the use of laser‐induced fluorescence for the inspection of printed circuit boards. Discusses how it works, how it compares with other inspection options and what advantages it offers, particularly for the inspection of low‐contrast materials. Concludes that laser‐based automated optical inspection (AOI) has major potential advantages compared with white‐light AOI equipment.
Phage Promoter-Based Methods for Sequencing and Screening for Mutations (1994)

Genomic amplification with transcript sequencing (GAWTS) (Stoflet et al., 1988; Sommer et al., 1990) is a generally applicable method for direct sequencing of PCR material. GAWTS is centered around the attachment of a phage promoter sequence (T7, SP6, or T3) to the 5′-end of one or both PCR primers. The phage promoter sequence allows the PCR product to be transcribed into RNA. Subsequently, the RNA is utilized as a single-stranded template for dideoxynucleotide sequencing with reverse transcriptase (Figure 18.1).
The Biology of Trichoplusia ni (Lepidoptera: Noctuidae). I. Life History and Behavior1 (1962)

Studies of Trichoplusia ni (Hübner), the cabbage looper, were conducted in, a greenhouse and laboratory at constant temperatures, and in the field in southern California. When larvae were reared on lima bean leaves, the total developmental time from egg deposition to adult emergence from the pupa averaged 95, 32, and 24 days for males, and 92, 30, and 23 days for females, at 14°, 23°, and 32° C, respectively. When cabbage was provided as food at 23°, 34 days were required for development of males and 35 days for females. The pupal stage of individuals reared at 14° tended to be lengthened disproportionately, and these pupae were heavier than those formed from larvae reared at 23° or 32°. Male pupae tended generally to be heavier than female pupae. Adults became active in the field shortly after sunset, but captures at a black light trap gave no evidence of definite peaks of nocturnal flight activity. However, fewer adults were captured after 11 p.m. than before, and the ratio of females to males generally declined as the night progressed. All matings observed among caged adults occurred after midnight, the average time of initiation being 2:10 a.m. No matings were observed until the second night after emergence from the pupa, and mature eggs were not found in the common oviduct of females until 2 days after emergence. Female adults maintained in the greenhouse at 27° successfully mated an average of 2.0 times. For cabbage loopers reared on lima bean leaves the ratio of males to females was 46:54. Males can be distinguished from females in large larvae by the appearance of the developing testes in the male, in pupae by the location of the genital pore, and in adults by the presence of characteristic light brown hairs on the abdomen of the male. A rearing procedure is described whereby the larvae were raised on the young primary leaves of lima beans growing in flats containing vermiculite. Behavior patterns observed during mating, oviposition, hatching, molting, and pupation are described.
On VLSI interconnects (2002)

The author reviews some recent approaches to the computation of transient response of VLSI circuits interconnected by transmission lines and discontinuities such as angled-bends. These approaches are based on modeling of the interconnects as subcircuits consisting of ordinary lumped elements, controlled sources and sections of ideal transmission lines (delay elements). In this way, the transient solution of the entire circuit can be obtained from a SPICE-like simulator, and FFT, discrete convolution or inversion of the Laplace transform can all be avoided. Examples of models of lossy transmission lines and 90 degrees bends are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Melting Points of Potential Liquid Organic Hydrogen Carrier Systems Consisting of <i>N</i>-Alkylcarbazoles (2016)

Liquid organic hydrogen carriers (LOHCs) represent an attractive concept for storing hydrogen by the hydrogenation of usually aromatic compounds. One of the best investigated LOHCs is N-ethylcarbazole because of its favorable thermodynamic properties. However, its high melting point of 343.1 K could be a major drawback particularly in mobile applications. Therefore, it is desired to decrease the melting point of N-ethylcarbazole without significantly changing favorable properties such as the storage density or the reaction behavior of the carrier compound. To investigate the solid–liquid behavior during hydrogenation, the melting points of pure N-ethylcarbazole derivatives with increasing degree of hydrogenation as well as the liquidus line of the binary mixture of N-ethylcarbazole and N-ethyl-dodecahydro-carbazole were measured. Because of their structural and chemical resemblance binary mixtures consisting of different alkylcarbazole combinations were analyzed regarding their potential for a melting point depression. By the appropriate combination of N-alkylcarbazoles, it is possible to achieve a considerable melting point decrease to 297.1 K.
Identification of a defective cAMP-stimulated Cl- channel in cystic fibrosis fibroblasts. (1987)

Cl- efflux from normal human fibroblasts is stimulated by elevation of cAMP and by elevation of intracellular free Ca2+. In both cases the stimulated Cl- transport occurs via electrically conductive pathways. In six lines of normal human fibroblasts, dibutyryl cAMP increased total Cl- efflux by an average of 13%. In six lines of fibroblasts from patients with cystic fibrosis, dibutyryl cAMP was without effect. The electrically conductive component of Cl- transport was increased an average of 30% by dibutyryl cAMP in normal cells and was unaffected by dibutyryl cAMP in cystic fibrosis cells. Stimulation of the Ca2+-sensitive Cl- channel by addition of A23187 increased Cl- efflux by an average of 30% in normal and 30% in cystic fibrosis fibroblasts. The data indicate that there is a defect in a cAMP-activated Cl- channel in cystic fibrosis fibroblasts.
Clinical Applicability of in vivo Reflectance Confocal Microscopy for the Diagnosis of Actinic Keratoses (2008)

BACKGROUND In vivo reflectance confocal microscopy (RCM) has been used for evaluation of the morphologic features of nonmelanoma skin cancer. The application of RCM for diagnosis of basal cell carcinoma has been reported; however, the evaluation of actinic keratoses (AKs) has only been the subject of preliminary studies. STUDY GOAL The goal of this study was to evaluate the applicability of RCM in the diagnosis of AK in correlation with routine histology. MATERIALS AND METHODS Forty-four Caucasians with a minimum of one AK participated in this study. Evaluation consisted of clinical examination, RCM, and routine histology, including a total of 46 AKs in the final analysis. Ten normal skin sites served as controls. RCM features of AK included parakeratosis, architectural disarray, and keratinocyte pleomorphism. Following blinded evaluations, sensitivity/specificity, kappa analysis, and Spearman's correlation were performed on all parameters. RESULTS Sensitivity/specificity values of RCM features ranged from 80% to 98.6%. The presence of architectural disarray and cellular pleomorphism appeared to be the best predictor of AK. CONCLUSION In summary, RCM may be a promising technology for the noninvasive detection of AK and as adjunct tool to clinical diagnosis and monitoring. However, the preliminary nature of this study warrants further investigations.
ThymesisFlow: A Software-Defined, HW/SW co-Designed Interconnect Stack for Rack-Scale Memory Disaggregation (2020)

With cloud providers constantly seeking the best infrastructure trade-off between performance delivered to customers and overall energy/utilization efficiency of their data-centres, hardware disaggregation comes in as a new paradigm for dynamically adapting the data-centre infrastructure to the characteristics of the running workloads. Such an adaptation enables an unprecedented level of efficiency both from the standpoint of energy and the utilization of system resources. In this paper, we present - ThymesisFlow - the first, to our knowledge, full-stack prototype of the holy-grail of disaggregation of compute resources: pooling of remote system memory. Thymesis-Flow implements a HW/SW co-designed memory disaggregation interconnect on top of the POWER9 architecture, by directly interfacing the memory bus via the OpenCAPI port. We use ThymesisFlow to evaluate how disaggregated memory impacts a set of cloud workloads, and we show that for many of them the performance degradation is negligible. For those cases that are severely impacted, we offer insights on the underlying causes and viable cross-stack mitigation paths.