gebhart/patrepeval huggingface dataset:
Über zweistufige Redoxsysteme, I (1964)

Abstract Es werden die allgemeinen konstitutionellen Voraussetzungen für Systeme mit drei Oxydationsstufen beschrieben. Dabei entspricht die mittlere Oxydationsstufe Radikalkationen, deren Farbe mit der von Cyaninfarbstoffen verglichen werden soll.
Methods for Booting an All Programmable System-on-Chip Over PCl Express Link (2017)

An All Programmable System-on-Chip (SoC) solution consisting of a hardened processor and a programmable fabric solution has been identified as a growing heterogeneous programmable platform catering to variety of application areas including communication, remote radio head, and software-defined radio and so on. The process to boot such a SoC with embedded processor and programmable fabric has been a challenge considering the complexity involved in multiple stages of booting. The boot sequence typically involves loading of first stage loader, configuring the programmable fabric with configuration bitstream followed by loading of user boot loader. Booting with typical boot devices like Quad Serial Peripheral Interface (QSPI), NAND or NOR flash results in increased boot time. The embedded PCI Express block in such SoC can be used as a carrier for the boot image including the user boot loader and the bitstream. The boot loader can be transferred from a remote host PC to the SoC's on chip memory over PCle link. Such boot process imparts significant improvement in boot time and ensures boot image security since the boot images can be stored in a secure processing system. Using boot over PCIe methodology, the authors have experimentally found 20x improvement in boot time over the state-of-the-art boot mechanisms.
Modeling Deepwater Reservoirs (2005)

Abstract Deepwater reservoirs pose significant challenges worldwide to companies exploring and producing such reservoirs because of the high exploration, development, and production costs. Great uncertainty and risk attend the evaluation of deepwater reservoirs because of the environment, sparse well control, and lack of direct measurement of reservoir properties. Proper modeling of deepwater reservoirs provides companies with tools to evaluate these reservoirs and quantify risks associated with their development. There are five critical areas in the process of modeling deepwater reservoirs. These are geological and geophysical modeling, reservoir characterization, reservoir flow modeling, facilities/flow assurance, and uncertainty/risk analyses. This paper presents methodologies found useful by experience in the modeling of deepwater reservoirs. Actual field cases describe our experience in using systematic steps based on the five critical areas to model the Zia reservoir, a Manatee reservoir in the Troika Basin, and the Magnolia reservoirs using the Markov Chain Monte Carlo technique.
Fast quantum-dot saturable absorber for passive mode-locking of solid-state lasers (2004)

In this work we present experimental data that demonstrates mode-locked operation of Yb:KYW solid state laser by using a QD structure combined with a distributed Bragg reflector (DBR) as a saturable absorber mirror. We also demonstrate here, a fast recovery time in this QD waveguide structure as measured using the pump-probe technique.
Multiple Failure Correction in the Time-Triggered Architecture (2004)

The Time-Triggered Architecture (TTA) is an architecture for safety-critical applications. Fault-tolerance mechanisms are therefor of upmost importance to ensure correct system operation in presence of failures as well as after transient disturbances. Currently the TTA tolerates one faulty component. Multiple transient failures are outside of the fault hypothesis of the TTA and scenarios can be established, after multiple transient failures, which cannot be corrected by the conventional TTA mechanism. Therefore, we propose an algorithm, for correction of the system after multiple transient failures, as an extension to the fault-tolerance mechanisms of the TTA. Furthermore, we discuss variations of this algorithm.
Nitrogen-Rich Polymers as Candidates for Energetic Applications (2012)

The same basics also apply when considering the use of polymers, instead of single molecules, as energetic ingredients. However, the quest for high densities and heats of formation appears somewhat more challenging in the case of polymers, since the polymerization process often requires specific chemical functions that may be detrimental to the desired energetic properties. Currently, the most commonly used polymers in the field get their energetic content only from explosophoric groups: NO2 for polyNIMMO (polynitratomethyl methyloxetane) or polyGLYN (polyglycidyl nitrate), N3 for GAP (glycidyl azide polymer), to name a few. This survey gives an overview of research efforts that have been devoted to the synthesis of macromolecules with high nitrogen contents. Such a unique property is expected to produce materials with particularly elevated heats of formation, thus making them very valuable in the field of energetic compounds.
A computer model of intracranial dynamics (2002)

A software model of intracranial dynamics was developed using existing relationships between patient physiology and brain dynamics. The relationship between the physiologic parameters arterial partial pressure of oxygen (PaO/sub 2/), arterial partial pressure of carbon dioxide (PaCO/sub 2/), mean arterial blood pressure (MABP), temperature (T) and brain dynamics were obtained from literature and were coded into software using Borland C. This computer model was integrated with a full scale patient simulator which generated the physiological inputs to the brain model. This integration allows users of the patient simulator to see the effects of their clinical interventions on brain dynamics through a real-time display. The display outputs the following intracranial variables: cerebral blood flow (CBF), cerebral blood volume (CBV), cerebral metabolic rate (CMRO/sub 2/), cerebral perfusion pressure (CPP), and intracranial pressure (ICP). The ability to visualize intracranial events as they are affected by physiology is a useful tool for teaching and training students.
Calculating horizontal stress orientations with full or partial knowledge of the tectonic stress tensor (2007)

Earthquakes potentially serve as abundant and cost-effective gauges of tectonic stress provided that reliable means exist of extracting robust stress parameters. Several algorithms have been developed for this task, each of which typically provides information on the orientations of the three principal stresses and a single stress magnitude parameter. A convenient way of displaying tectonic stress results is to map the azimuth of maximum horizontal compressive stress, which is usually approximated using the azimuth of the larger subhorizontal principal stress. This approximation introduces avoidable errors that depend not only on the principal stress axes' plunges but also on the value of the stress magnitude parameter. Here we outline a method of computing the true direction of maximum horizontal compressive stress (S H ) and show that this computation can be performed using only the four stress parameters obtained in routine focal mechanism stress estimation. Using theoretical examples and new stress inversion results obtained with focal mechanism data from the central Grmsey lineament, northern Iceland, we show that the S H axis may differ by tens of degrees from its commonly adopted proxy. In order to most appropriately compare tectonic stress estimates with other geophysical parameters, such as seismic fast directions or geodetically measured strain rate tensors, or to investigate spatiotemporal variations in stress, we recommend that full use be made of the routinely estimated stress parameters and that a formal axis of maximum horizontal compression be calculated.
Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials (2010)

Tocilizumab in combination with MTX as a treatment for RA is associated with a small but significantly increased risk of AEs, which is comparable with that of other biologics. Vigilance for untoward effects is, therefore, imperative in any patient treated with these immuno-suppressive agents.
Synthesis of a carboxyl-containing conducting oligomer and non-covalent sidewall functionalization of single-walled carbon nanotubes (2005)

A carboxyl-containing conducting oligomer, poly(pyrenebutyric acid) (PPBA), has been synthesized for non-covalent sidewall functionalization of single-walled carbon nanotubes (SWNTs) by direct oxidation of α-pyrenebutyric acid (PBA) in boron trifluoride diethyl etherate (BFEE) containing SWNTs. The initial feeding weight ratio of the monomer and SWNTs can strongly influence the thickness of the oligomer coating on SWNTs and also the diameter of the fibril nanocomposites. The pyrene moieties of PPBA interacted with the sidewalls of SWNTs because of their large aromatic rings, which meant that the composite could be stably dispersed in many common organic solvents and aqueous alkaline solutions. The structure and optical properties of PPBA and SWNT/PPBA composites have also been studied.
Innovative technologies of head injury physiological monitoring (2000)

The World Health Organization estimates that in 2010 one of ten families in developed countries will have a member with head or spinal cord injury. The systems of head and spinal cord physiological monitoring as well as the treatment of injured patient according to the presence of diagnostic information allow us to decrease the mortality of patient and their invalidity. However, the existing head injury monitoring technologies are invasive. This paper analyses scientific and patent information designed for the development of physiological monitoring technologies. Also the proposed technological solutions have been systematized. It is shown that innovative technologies for monitoring of the cerebral blood flow autoregulation, cerebral blood volume pulse and slow waves also for the registration of the reactions to the neurodiagnostic tests can be developed on the basis of the precise measurement of brain parenchyma acoustic characteristics. The innovative technological equipment for such measurement has been developed. The clinical studies proving the validity of the concepts chosen have been carried out. For the first time the innovative method was designed for the ICP absolute value measurement without the necessity of individual calibration of system non-invasive meter - patient.
Effect of Aspect Ratio on the Light Output of Scintillators (2012)

The influence of the geometry of the scintillators is presented in this paper. We focus on the effect of narrowing down the section of crystals that have a given length. The light output of a set of crystals with very similar scintillating properties but different geometries measured with several coupling/wrapping configurations is provided. We observe that crystals shaped in thin rods have a lower light output as compared to bulk or sliced crystals. The effect of unpolishing the crystal faces is also investigated, and it is shown that highest light outputs are not necessarily obtained with crystals having all faces polished. Simulation results based on a realistic model of the crystal that implements light scattering on the crystal edges are in agreement with the experimental data. Fine-tuning of this model would allow us to further explore the details of light propagation in scintillators and would be highly valuable to fast timing detection and highly granular detectors.
Macromol. Rapid Commun. 22/2007 (2007)

Cover: It was found that binary blending of block copolymers could make the cylindrical domains align perpendicular to a non‐neutral substrate. In combination with the graphoepitaxy technique, an array of highly ordered perpendicular cylinders with a domain spacing of less than 25 nm was produced. Further details can be found in the Full Paper by F. Chen, S. Akasaka, T. Inoue, M. Takenaka, H. Hasegawa, * and H. Yoshida on page 2137.
A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration (2018)

Mutations in CEP290 cause ciliogenesis defects, leading to diverse clinical phenotypes, including Leber congenital amaurosis (LCA). Gene therapy for CEP290-associated diseases is hindered by the 7.4 kb CEP290 coding sequence, which is difficult to deliver in vivo. The multi-domain structure of the CEP290 protein suggests that a specific CEP290 domain may complement disease phenotypes. Thus, we constructed AAV vectors with overlapping CEP290 regions and evaluated their impact on photoreceptor degeneration in Cep290<sup>rd16/rd16</sup> and Cep290<sup>rd16/rd16</sup>;Nrl<sup>-/-</sup> mice, two models of CEP290-LCA. One CEP290 fragment (the C-terminal 989 residues, including the domain deleted in mutant mice) reconstituted CEP290 function and resulted in cone preservation and delayed rod death. The CEP290 C-terminal domain also improved cilia phenotypes in mouse embryonic fibroblasts and iPSC-derived retinal organoids carrying the Cep290<sup>rd16</sup> mutation. Our study strongly argues for in trans complementation of CEP290 mutations by a cognate fragment and suggests therapeutic avenues.
Algorithms and Arithmetic Operators for Computing the ηT Pairing in Characteristic Three (2008)

Since their introduction in constructive cryptographic applications, pairings over (hyper)elliptic curves are at the heart of an ever increasing number of protocols. Software implementations being rather slow, the study of hardware architectures became an active research area. In this paper, we discuss several algorithms to compute the ηT pairing in characteristic three and suggest further improvements. These algorithms involve addition, multiplication, cubing, inversion, and sometimes cube root extraction over GF(3m). We propose a hardware accelerator based on a unified arithmetic operator able to perform the operations required by a given algorithm. We describe the implementation of a compact coprocessor for the field GF(397) given by GF(3)[x]/(x97+x12+2), which compares favorably with other solutions described in the open literature.
Role of Intracellular Calcium in NI-35-Evoked Collapse of Neuronal Growth Cones (1993)

A myelin-associated protein from the central nervous system, the neurite growth inhibitor NI-35, inhibits regeneration of lesioned neuronal fiber tracts in vivo and growth of neurites in vitro. Growth cones of cultured rat dorsal root ganglion neurons arrested their growth and collapsed when exposed to liposomes containing NI-35. Before morphological changes, the concentration of free intracellular calcium ([Ca2+]i) showed a rapid and large increase in growth cones exposed to liposomes containing NI-35. Neither an increase in [Ca2+]i nor collapse of growth cones was detected in the presence of antibodies to NI-35. Dantrolene, an inhibitor of calcium release from caffeine-sensitive intracellular calcium stores, protected growth cones from collapse evoked by NI-35. Depletion of these caffeine-sensitive intracellular calcium stores prevented the increase in [Ca2+]i evoked by NI-35. The NI-35-evoked cascade of intracellular messengers that mediates collapse of growth cones includes the crucial step of calcium release from intracellular stores.
MEMS-based integrated-circuit mass-storage systems (2000)

article Free AccessMEMS-based integrated-circuit mass-storage systems Authors: L. Richard Carley Carnegie Mellon Univ., Pittsburgh, PA Carnegie Mellon Univ., Pittsburgh, PAView Profile , Gregory R. Ganger Carnegie Mellon Univ., Pittsburgh, PA Carnegie Mellon Univ., Pittsburgh, PAView Profile , David F. Nagle Carnegie Mellon Univ., Pittsburgh, PA Carnegie Mellon Univ., Pittsburgh, PAView Profile Authors Info & Claims Communications of the ACMVolume 43Issue 11Nov. 2000 pp 72–80https://doi.org/10.1145/353360.353367Published:01 November 2000Publication History 39citation1,582DownloadsMetricsTotal Citations39Total Downloads1,582Last 12 Months50Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteView all FormatsPDF
<i>Gases</i>, <i>liquids</i>, <i>and</i> <i>solids</i> (1980)

First Page
Management science in practice (2008)

TABLE OF CONTENTS<br/><br/>PART I: MANAGEMENT SCIENCE.<br/><br/>Chapter 1: What is Management Science?<br/><br/>Chapter 2: Management Science interventions.<br/><br/>PART 2: MODELLING TECHNIQUES.<br/><br/>Chapter 3: Problem structuring techniques.<br/><br/>Chapter 4: Multi-methodology.<br/><br/>Chapter 5: Analysis techniques.<br/><br/>PART 3: PRACTICAL SKILLS.<br/><br/>Chapter 6: The proposal stage.<br/><br/>Chapter 7: Data.<br/><br/>Chapter 8: Appropriate modeling.<br/><br/>Chapter 9: Creativity.<br/><br/>Chapter 10: Ancilliary practical skills.<br/><br/>PART 4: PRACTICE.<br/><br/>Chapter 11: OR/MS groups.<br/><br/>Chapter 12: Ethics.<br/><br/>Chapter 13: Reflective practice.<br/><br/>The final note: the future.<br/><br/>References.
Ultrasound radiating performances of piezoelectric micromachined ultrasonic transmitter (2005)

This letter reports on a membrane-type piezoelectric micromachined ultrasonic transducer (pMUT). It consists of 3.5 or 7μm thick composite lead zirconate titanate (PZT) film on a multilayered membrane and works as an ultrasonic transmitter. The ultrasound-radiating performance of the transmitter, in response to a continuous ac driving voltage, has been tested systematically. The generated sound pressure level at resonance frequency of the transmitter varies with the applied dc bias and driving voltage and can exceed 110dB at a measuring distance of 12mm. For a given square membrane with the same multilayer structure and thickness, the resonance frequency of the transmitter is inversely proportional to the area of the membrane, and can be further tuned by control of the poling conditions of the PZT film or the applied dc bias.
Biomarkers of Presbycusis and Tinnitus in a Portuguese Older Population (2017)

<b>Introduction:</b> Presbycusis or age-related hearing loss (ARHL) is a ubiquitous health problem. It is estimated that it will affect up to 1.5 billion people by 2025. In addition, tinnitus occurs in a large majority of cases with presbycusis. Glutamate metabotropic receptor 7 (<i>GRM7</i>) and <i>N</i>-acetyltransferase 2 (<i>NAT2</i>) are some of the genetic markers for presbycusis. <b>Objectives:</b> To explore patterns of hearing loss and the role of <i>GRM7</i> and <i>NAT2</i> as possible markers of presbycusis and tinnitus in a Portuguese population sample. <b>Materials and Methods:</b> Tonal and speech audiometry, tinnitus assessment, clinical interview, and DNA samples were obtained from patients aged from 55 to 75 with or without tinnitus. <i>GRM7</i> analysis was performed by qPCR. Genotyping of single nucleotide polymorphisms (SNPs) in <i>NAT2</i> was performed by PCR amplification followed by Sanger sequencing or by qPCR. <b>Results:</b> We screened samples from 78 individuals (33 men and 45 women). T allele at <i>GRM7</i> gene was the most observed (60.3% T/T and 33.3% A/T). Individuals with a T/T genotype have a higher risk for ARHL and 33% lower risk for tinnitus, compared to individuals with A/A and A/T genotype, respectively. Being a slow acetylator (53%) was the most common <i>NAT2</i> phenotype, more common in men (55.8%). Intermediate acetylator was the second most common phenotype (35.9%) also more frequent in men (82.6%). Noise exposed individuals and individuals with 'high frequency' hearing loss seem to have a higher risk for tinnitus. Our data suggests that allele AT of <i>GRM7 c</i>an have a statistically significant influence toward the <i>severity</i> of tinnitus. <b>Conclusion:</b> For each increasing year of age the chance of HL increases by 9%. The risk for ARHL was not significantly associated with <i>GRM7</i> neither <i>NAT2</i>. However, we cannot conclude from our data whether the presence of T allele at <i>GRM7</i> increases the odds for ARHL or whether the A allele has a protective effect. Genotype A/T at <i>GRM7</i> could potentially be considered a biomarker of tinnitus severity. This is the first study evaluating the effect of <i>GRM7</i> and <i>NAT2</i> gene in tinnitus.
An Effective-Mass Theory for Bright Gap Solitons in Optical Lattices (2005)

A one-band effective-mass (EFM) theory was developed to study the properties of the localized states of a Bose-Einstein condensate (BEC) in a periodic optical potential with either attractive or repulsive atom interactions. The localized states of the BEC are solitons in the gaps or gap solitons. The analytic solutions of the gap solitons are a Bloch function from periodicity, modulated by a soliton envelope function of the nonlinear Schrödinger equation. The soliton width is determined by the detuning chemical potential from the band edge. The detuning chemical potential in the nonlinear Schrödinger equation indicates that not all the atoms in the condensate are used for forming gap solitons, and that some atoms form the background of nonlinear modes. The background atoms are determined by the chemical potential at the band edge. The gap solitons form on top of the background atoms. PACS numbers: 03.75.Lm, 03.75.Kk, 05.30.Jp I.
Hepatic artery pump infusion: toxicity and results in patients with metastatic colorectal carcinoma. (1984)

5-Fluorodeoxyuridine (FUDR) was infused continuously into the hepatic artery for 14 days a month at an initial dose of 0.3 mg/kg per day in 45 patients with liver metastases from colorectal carcinoma. In 41 adequately treated patients, partial responses (greater than 50% tumor regression) were observed in 12 (52%) of 23 previously untreated patients, and three (17%) of 18 previously treated patients. Severe gastrointestinal toxicity was endoscopically documented in 19 (46%) patients; 12 (29%) had discrete ulcers, and seven had diffuse gastritis or duodenitis. Significant hepatic-enzyme abnormality was seen in 29 patients (71%) and an elevated serum bilirubin in nine (22%). A significant factor influencing survival was the extent of tumor involvement in the liver; patients with less than 20% involvement have not yet reached a median survival at 13 months versus six months for patients with greater than 60% involvement (p less than 0.001). Studies comparing regional to systemic chemotherapy and stratifying patients according to the extent of hepatic tumor burden are needed to assess the true impact of hepatic infusion on response and survival.
Minsize2: a Computer Program for Determining Effect Size and Minimum Sample Size for Statistical Significance for Univariate, Multivariate, and Nonparametric Tests (1999)

The American Psychological Association’s editorial style urges authors to provide effect size estimates. Several journals, including Educational and Psychological Measurement, have adopted author guidelines that call for determining the minimum sample size necessary for a given result to have been declared statistically significant. MINSIZE2, a computer program that permits the user to determine both effect size and the minimum sample size needed for the results of a given analysis to be statistically significant, is described. Program applications for statistical significance tests for univariate, multivariate, and nonparametric statistics are provided. Explanation of the program’s operation is given, and examples are furnished.