gebhart/patrepeval huggingface dataset:
Temperature‐Induced Changes in the Dynamic Rheological Behavior and Size Distribution of Polymeric Proteins for Glutens from Wheat Near‐Isogenic Lines Differing in HMW Glutenin Subunit Composition (2000)

ABSTRACT Viscoelasticity of hydrated gluten depends on composition of HMW gluten subunits (GS), size distribution of glutenin polymers, and proteinprotein interactions. Glutens extracted from four near‐isogenic lines with differing HMW‐GS were analyzed. Rheological properties were studied by dynamic assay in shear. Size distribution of prolamins was determined by sequential extraction and size‐exclusion HPLC. Assays performed at 20°C confirmed that viscoelasticity was determined by large glutenin polymers. The abundance of large glutenin polymers depended on the HMW‐GS composition of the lines. Difference of functionality linked to subunit structure was highlighted by comparing the behaviors of the 1A/1B null and 1A/1D null lines. Glutens were submitted to heating and cooling cycles, with or without an SH‐blocking agent (N‐ethylmaleimide [NEMI]). At 20–40°C, no irreversible changes of the mechanical properties occurred. Thermal treatment affected chain mobility, and possibly H bonds, but not the chemical structure of the network. At >40°C, irreversible rheological changes were observed without NEMI. Irreversibility was mainly due to chemical modifications affecting the polymer size distribution through SH‐SS exchange reactions. The sensitivity of gluten to temperature depended on subunit composition.
Electroless nanowelding of silver nanowires at room temperature (2014)

Silver nanowires (Ag NWs) using polyvinylpyrrolidone (PVP) surfactants were coated on either polyethylene terephthalate (PET) or glass substrates. The resistance of the Ag NW film was very high due to the PVP molecules wrapping around the Ag NWs and preventing good electrical contacts between them. We performed an Ag electroless deposition (ELD) on the Ag NW film at room temperature and achieved the welding of Ag NWs by enhancing the deposition of Ag right at the junctions of the two crossing wires. The welding of Ag NWs drastically reduced the sheet resistance (Rsh) of the film from 17 000 to 20 ohm sq−1 for only a 2 min treatment. By conducting the Ag ELD on the PVP-removed Ag NW film annealed at 200 °C, we showed that the PVP molecules concentrated at the junctions were responsible for the nanowelding behavior. In addition, both ethylenediamine (EDA) and ammonium hydroxide (NH4OH) could mildly etch the Ag NWs to remove PVP from the wires at room temperature, improving the contacts between Ag NWs and thus reducing the Rsh of the Ag NW film. An organic light emitting diode with ELD-treated Ag NW film was prepared to demonstrate the applicability of the nanowelding technique for conductivity enhancement. The better performance of the device based on ELD-treated Ag NW film compared with that on Ag thin film was due to the higher degree of light transmittance and work function of the Ag NWs.
Endoproteolysis at Tetrabasic Amino Acid Sites in Procalcitonin Gene-Related Peptide by Pituitary Cell Lines (1997)

The specificity of neuroendocrine prohormone convertases for tetrabasic amino acid sites was investigated. Mutations were introduced into the tetrabasic cleavage site of the procalcitonin gene-related peptide (proCGRP) cDNA and these mutated cDNA's were expressed in AtT-20 cells which predominantly express the endoprotease prohormone convertase-1 (PC1/3), and in GH3 cells which predominantly express prohormone convertase-2 (PC2). Mutations were introduced into the proCGRP cDNA which converted the wild-type ArgArgArgArg site to LysLysArgArg and ArgArgLysLys, and the proCGRP variants were stably transfected into AtT-20 and GH3 cells. ProCGRP containing each of the LysLysArgArg permutations were efficiently cleaved in both AtT-20 and GH3 cells. Cleavage of LysLysArgArg in exogenous proCGRP, but not in endogenous POMC, suggests that the specificity of cleavage at tetrabasic sites is not defined solely by the endoproteases expressed by the cell or by the amino acid sequence at the cleavage site, but is also dependent on the structure of the propeptide.
Analysis of the catalase-hydrogen peroxide intermediate in coupled oxidations (1973)

In previous communications, we considered the kinetics of the catalase-H202 intermediate in coupled oxidations ofthe isolated liver catalase In those cases, it was possible to record the kinetics of formation of the intermediate by H202 pulses, and solve for the H202 concentration. In most ofthe cases, however, only the analysis of steady-state effects are feasible and will be useful for the further study on the catalase reaction, especially in a system such as the perfused liver. It seems appropriate, therefore, to extend the analysis.
High Harmonic Imaging of Few-Cycle Laser Pulses (2003)

We show that the strength of the central electric field peaks in a few-cycle laser pulse can be recovered from a frequency-time image of the high harmonic spectrum generated in a gas volume. Pulse intensity, duration, and also the carrier-envelope phase phi(CE) can be determined. A simple and robust observable is defined that provides a gauge of phi(CE) for pulse durations up to three optical cycles, corresponding to 7.8 fs FWHM at the Ti:sapphire wavelength of 800 nm.
Supportive Communication Among Nurses: Effects on Commitment, Burnout, and Retention (1994)

This article presents the results of a research project designed to determine the impact of specific types of supportive communication on burnout, organizational commitment, and retention for practicing nurses. Hypotheses regarding the influence of informational, emotional, and instrumental social support were tested with survey data gathered from a large group of employed nurses. Results indicate targeted effects of instrumental and informational support, but broader effects for emotional support in organizational outcomes. Although significant relations were found for supportive communication and personal control, results indicate that other rationales explaining the link between social support and burnout may be warranted. The implications for theory and research are discussed.
Emerging targets to monitor and overcome docetaxel resistance in castration resistant prostate cancer (Review) (2014)

Drug development for castration resistant prostate cancer (CRPC) is challenging, since this cancer is still associated with high mortality and limited therapeutic options. In 2004, docetaxel became the first-line chemotherapy for CRPC improving survival by a few months and remains the standard of care in CRPC patients. However, existing or developing resistance to docetaxel in patients is the main limitation of its efficacy. The present review presents the molecular mechanisms involved in docetaxel toxicity and in docetaxel resistance in prostate cancer cells. We outlined the endogenous mechanisms of resistance and the role of tumor microenvironment in the resistance of CRPC to docetaxel. This has led us to focus on molecules associated with resistance, such as the molecular chaperones heat shock proteins (HSPs) and clusterin (CLU), and the cytokines interleukin-6 (IL-6) and the divergent member of the tumor growth factor family MIC-1 (macrophage inhibitory cytokine-1 also named GDF-15). We discuss their interest as blood-based markers to monitor docetaxel resistance. Finally, new therapies intended to overcome docetaxel resistance of CRPC targeted on these molecular resistance pathways are present.
Odor Threshold Determinations of 53 Odorant Chemicals (1969)

In order to assist in assessing potential odor problems arising from chemical manufacturing operations, the odor thresholds of 53 commercially important odorant chemicals have been determined using a standardized and defined procedure. The odor threshold data previously available have shown wide variation reflecting the diversity of procedures and techniques used. Factors that may affect the odor threshold measurement include the mode of presentation of the stimulus to the observer, the influence of extraneous odorants in the presentation system, the type of observer used, the definition of the odor response, the treatment of the data obtained, and the chemical purity of the odorant. The experimental approach used has minimized these variations. The odorants were presented to a trained odor panel in a static air system utilizing a low odor background air as the dilution medium. The odor threshold is defined as the first concentration at which all panel members can recognize the odor. The effect of chemical purity has been determined by measuring the odor threshold of materials representing different modes of manufacture or after purification by gas chromatographic procedures. The threshold concentrations range over six orders of magnitude. Trimethylamine exhibited the lowest threshold (0.00021 ppm volume); methylene chloride was not recognizable below 214 ppm. Of the 53 chemicals, sulfur bearing compounds exhibit low threshold values on the order of parts per billion. Aside from the sulfides, it is not possible to anticipate the odor threshold of a material based on its chemical structure or functionality.
Chemical Constituents of Brazilian Propolis and Their Cytotoxic Activities (1998)

The EtOAc-soluble fraction of the MeOH extract of propolis afforded a new prenylated chromane derivative, 3-hydroxy-2, 2-dimethyl-8-prenylchromane-6-propenoic acid (1), along with 22 known compounds, 2-23. Of the known compounds, 4, 7, 12-19, and 22 were isolated for the first time from propolis, and the absolute configuration of 23 was established as (2S,3R). Investigation suggested that Baccharis spp. are a significant source of tropical Brazilian propolis, in addition to Clusia minor, Clusia major, and Araucaria heterophylla. All the compounds were tested for their cytotoxicity toward human HT-1080 fibrosarcoma and murine colon 26-L5 carcinoma cells. Among these compounds, 9 and 19-21 showed potent cytotoxicity, having ED50 values equal to or less than 10 microg/mL.
1550 nm band optical input module with superconducting single-flux-quantum circuit (2010)

We developed an optical input module with a superconducting single-flux-quantum (SFQ) circuit for application of ultrafast photonic networks in the near future. The optical input module, consisting of a built-in photodiode (PD) with a coplanar waveguide transmission line, was fabricated on an InP substrate and flip-chip bonded with the SFQ circuit on a Si substrate. The fabricated PD showed photosensitivities of more than 0.2 A/W for the wavelength range 1480 to 1530 nm at 4.2 K. SFQ pulses were generated by less than 1 mW optical pulse input.
Service discovery using Bloom filters (2006)

A protocol to perform service discovery in adhoc networks is introduced in this paper. Attenuated Bloom filters are used to distribute services to nodes in the neighborhood and thus enable local service discovery. The protocol has been implemented in a discrete event simulator to investigate the behavior in case of a multihop mobile ad-hoc network with nodes that all have services to offer. Methods to optimize the used bandwidth, which is a scarce resource in wireless networks, are investigated. Experiments performed with the simulator suggest that the proposed service discovery system enables users to find local services in a multihop ad-hoc network efficiently. The costs for advertising can be kept low, whereas the additional costs for queries set due to so-called false positives are moderate. 1
[On the use of biodestructor "Disoil" for the purification of soil from petroleum wastes]. (1999)

Sanitation of territories polluted with oil products is possible and quite effective through biodestructor produced in Russia on the basis of nonpathogenic yeast lines. Oil content of the soil lowers by 60-78%. Self-clearance of the soil is preserved, toxicity level of the soil does not increase.
Significant enhancement of the upper critical field in the two-gap superconductor MgB2 by selective tuning of impurity scattering (2003)

We report a significant enhancement of the upper critical field $H_{c2}$ of different $MgB_2$ samples alloyed with nonmagnetic impurities. By studying films and bulk polycrystals with different resistivities $\rho$, we show a clear trend of $H_{c2}$ increase as $\rho$ increases. One particular high resistivity film had zero-temperature $H_{c2}(0)$ well above the $H_{c2}$ values of competing non-cuprate superconductors such as $Nb_3Sn$ and Nb-Ti. Our high-field transport measurements give record values $H_{c2}^\perp (0) \approx 34T$ and $H_{c2}\|(0) \approx 49 T$ for high resistivity films and $H_{c2}(0)\approx 29 T$ for untextured bulk polycrystals. The highest $H_{c2}$ film also exhibits a significant upward curvature of $H_{c2}(T)$, and temperature dependence of the anisotropy parameter $\gamma(T) = H_{c2}\|/ H_{c2}^\perp$ opposite to that of single crystals: $\gamma(T)$ decreases as the temperature decreases, from $\gamma(T_c) \approx 2$ to $\gamma(0) \approx 1.5$. This remarkable $H_{c2}$ enhancement and its anomalous temperature dependence are a consequence of the two-gap superconductivity in $MgB_2$, which offers special opportunities for further $H_{c2}$ increase by tuning of the impurity scattering by selective alloying on Mg and B sites. Our experimental results can be explained by a theory of two-gap superconductivity in the dirty limit. The very high values of $H_{c2}(T)$ observed suggest that $MgB_2$ can be made into a versatile, competitive high-field superconductor.
Recognizing handwritten text (1991)

Notebook computers, using stylus input, are currently a hot topic among PC manufacturers. Handwriting recognition may be an important component of such systems, but only if everyday sloppy handwriting can be accommodated. If recognizes require unnaturally neat or boxed character input, such systems may fail in the marketplace. Neural nets have shown excellent performance at handwriting recognition.
Isolation and characterization of tetramethyltellurium(IV) (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and characterization of tetramethyltellurium(IV)Robert W. Gedridge, Daniel C. Harris, Kelvin T. Higa, and Robin A. NissanCite this: Organometallics 1989, 8, 12, 2817–2820Publication Date (Print):December 1, 1989Publication History Published online1 May 2002Published inissue 1 December 1989https://pubs.acs.org/doi/10.1021/om00114a014https://doi.org/10.1021/om00114a014research-articleACS PublicationsRequest reuse permissionsArticle Views216Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Sensitive Viral Capture Assay for Detection of Plasma Viremia in HIV-Infected Individuals (1992)

Human immunodeficiency virus was detected in the serum/plasma of individuals infected with human immunodeficiency virus (HIV) after capture of virions on microparticles coated with monoclonal antibodies to external and transmembrane proteins of HIV-1. We analyzed serial samples obtained from 6 individuals who seroconverted, 18 asymptomatic, and 12 AIDS patients. HIV-1 RNA was detected in all (29/29) seropositive samples and in 6 seronegative samples immediately preceding seroconversion. In contrast, HIV antigen was detected in 13/29 (45%) of seropositive samples. HIV-1 RNA was also detected in 3 antigen-negative samples from one individual 8-5 months prior to seroconversion and in one sample from another person 2 days before antigen positivity. The intensity of the polymerase chain reaction (PCR) signal paralleled the concentration of HIV antigen. Conversely, seropositive HIV antigen-negative samples gave a weaker PCR signal. HIV-1 RNA was detected in 10/18 (60%) samples from asymptomatic, HIV antigen-negative, individuals and in 11/12 (92%) specimens obtained from AIDS patients. The viral capture method may provide a sensitive, specific, and semiquantitative means of detecting circulating HIV at all stages of infection.
Purification and Amino Acid Sequence of the Linoleate Isomerase Produced from Butyrivibrio fibrisolvens A - 38 (1996)

Molecular weight and partial amino acid sequence of the cis,9-cis,12-octadecadienoate isomerase(linoleate isomerase) of Butyrivibrio fibrisolvens A-38 were determined. Linoleate isomerase was isolated from the bacteria cultured anaerobically and purified by ultracentrifugation in conjunction with Sepharose 6B column chromatography, Phenyl sepharose 4B column chromatography and fast performance liquid chromatography(FPLC). The isomerase was a single polypeptide with 19KD of molecular weight, when determined by SDS-PAGE. Fourteen amino acids sequence of N-terminal of the linoleate isomerase was N-GEIDKYPRRIIKQQ determined by Edman method.
Adaptive equalization for advanced television (1992)

The author presents an overview of the adaptive equalization process, including various equalizer topologies and error signal generation schemes, for 16 quadrature amplitude modulation (QAM) digital transmission systems. Four equalizer structures, along with the concept of blind equalization, are discussed. Simulation results for simple theoretical channels indicate that equalizer performance is a function of the topology, error generation, and underlying transmission channel.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Expression of BRCA1 and FAC1 in primary sporadic breast cancers. (2008)

We have previously described a +ACA BRCA1 promoter polymorphism that creates a FAC1 transcriptional repressor binding site (AACAACAC), which may confer FAC1‐mediated transcriptional repression (depending on the BRCA1 promoter genotype). To explore the relationship between BRCA1 and FAC1 expression in primary breast cancers, we performed immunostaining on 69 luminal A and B subtype sporadic breast cancers (ER+, PR+, HER2+/−). Most tumors are positive for BRCA1 expression (40/69, 58%), while a subset express reduced BRCA1 levels (29/69, 42%). The majority of these tumors (64/69, 93%) are positive for FAC1 expression: 27/64 (42%) express cytoplasmic FAC1 (cFAC1), 23/64 (36%) express both cFAC1 and nuclear FAC1 (nFAC1) and 14/64 (22%) express nFAC1 only. Among tumors with reduced BRCA1 expression, 55% (16/29) are positive for nFAC1 expression (which represents 43% (16/37) of nFAC1 expressing tumors that have reduced BRCA1 protein expression). This data suggests that most primary breast tumors are positive for FAC1 expression, and that 58% of FAC1 expressing tumors have some degree of nuclear FAC1 expression. It is intriguing to speculate that nFAC1 may modify gene expression in breast tumors, resulting in repression of normal BRCA1 expression, and contributing to breast carcinogenesis. Support: NIH CA78343, Komen Foundation BCTR0100575, Friends For an Earlier Breast Cancer Test.
PicSOM: self-organizing maps for content-based image retrieval (2003)

Content-based image retrieval is an important approach to the problem of processing the increasing amount of visual data. It is based on automatically extracted features from the content of the images, such as color, texture, shape and structure. We have started a project to study methods for content-based image retrieval using the self-organizing map (SOM) as the image similarity scoring method. Our image retrieval system, named PicSOM, can be seen as a SOM-based approach to relevance feedback which is a form of supervised learning to adjust the subsequent queries based on the user's responses during the information retrieval session. In PicSOM, a separate tree structured SOM (TS-SOM) is trained for each feature vector type in use. The system then adapts to the user's preferences by returning her more images from those SOMs where her responses have been most densely mapped.
Latent semantic analysis-based image auto annotation (2010)

The image retrieval is a particular case of information retrieval. It adds more complex mechanisms to relevance image retrieval: visual content analysis and/or additional textual content. The image auto annotation is a technique that associates text to image, and permits to retrieve image documents as textual documents, thus as in information retrieval. The image auto annotation is then an effective technology for improving the image retrieval. In this work, we propose the AnnotB-LSA algorithm in its first version for the image auto-annotation. The integration of the LSA model permits to extract the latent semantic relations in the textual describers and to minimize the ambiguousness (polysemy, synonymy) between the annotations of images.
Transduction of Escherichia coli trp Genes in Salmonella typhimurium and Effect of N-Methyl-N'-Nitro-N-Nitrosoguanidine on Transduction with Heterogenotic DNA (1983)

P1Kc-mediated transduction of Escherichia coli trp genes occurred at a frequency of about 10(-8) in Salmonella typhimurium trp strains carrying mutations determining sensitivity to P1 and a low level of restriction enzymes. Heterospecific transductants were analysed by using them as donors in second-stage transductions mediated by bacteriophage KBint. One class of heterospecific transductants had the phenotype Trp+ Pro- but were extremely unstable and reverted at high frequency (up to 80%) to the parental phenotype. The Trp+ Pro- phenotype probably represents insertions of the E. coli trp genes in the S. typhimurium pro genes. It was stable in a RecA background. Haploid Pl-mediated heterogenotes exhibited various degrees of homology with the trp region of S. typhimurium in KB-mediated second-stage transductions: one heterogenote (MA427), which transduced the linked markers trp, cysB and pyrF very poorly, was used to look at the effects of the mutagen N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in stimulating heterologous recombination and to derive a method for positive selection of linked mutations. Following treatment with MNNG, heterospecific Trp+ transductants were obtained with MA427 as donor. Their yield was maximal immediately after MNNG treatment but decreased and even disappeared when transductions were carried out a few hours later. This transient process is thought to represent MNNG-induced conversion of abortive transductants to complete transductants. On the other hand, phenotypic analysis of MNNG-induced Trp+ heterologous transductants revealed the presence of mutations of various phenotypes. In particular, the antimutator phenotype was recognized in 15 clones among 110 MNNG-induced recombinants tested. However, most of these mutations seemed not to influence heterologous recombination.