gebhart/patrepeval huggingface dataset:
Fast candidate generation for real-time tweet search with bloom filter chains (2013)

The rise of social media and other forms of user-generated content have created the demand for real-time search: against a high-velocity stream of incoming documents, users desire a list of relevant results at the time the query is issued. In the context of real-time search on tweets, this work explores candidate generation in a two-stage retrieval architecture where an initial list of results is processed by a second-stage rescorer to produce the final output. We introduce Bloom filter chains, a novel extension of Bloom filters that can dynamically expand to efficiently represent an arbitrarily long and growing list of monotonically-increasing integers with a constant false positive rate. Using a collection of Bloom filter chains, a novel approximate candidate generation algorithm called BWand is able to perform both conjunctive and disjunctive retrieval. Experiments show that our algorithm is many times faster than competitive baselines and that this increased performance does not require sacrificing end-to-end effectiveness. Our results empirically characterize the trade-off space defined by output quality, query evaluation speed, and memory footprint for this particular search architecture.
A new staging system based on tumor volume in gastric cancer. (2001)

The above findings suggest that a new staging system based on tumor volume may have advantages over the conventional staging system in the assessment of gastric cancer.
Protection of Mice with Recombinant Influenza Virus Neuraminidase (2004)

Contemporary influenza vaccines are standardized with respect to their content of hemagglutinin, the major virus antigen. Although the immunizing effect of viral neuraminidase--the less abundant of the 2 major surface glycoproteins--has been well documented in experimental animals, the importance of the purified recombinant protein has not yet been adequately assessed in animals or humans. We demonstrate that different lots of a baculovirus-derived recombinant N2 protein, in the absence of other influenza virus proteins, can induce neuraminidase-specific antibodies, reduce the replication of both homologous and heterovariant virus in mice, and suppress disease, as it is manifested by total body weight loss.
CIZ1, a p21<sup>Cip1/Waf1</sup>‐interacting protein, functions as a tumor suppressor in vivo (2013)

CIZ1 is a nuclear protein involved in DNA replication and is also implicated in human diseases including cancers. To gain an insight into its function in vivo, we generated mice lacking Ciz1. Ciz1-deficient (Ciz1(-/-)) mice grew without any obvious abnormalities, and Ciz1(-/-) mouse embryonic fibroblasts (MEFs) did not show any defects in cell cycle status, cell growth, and DNA damage response. However, Ciz1(-/-) MEFs were sensitive to hydroxyurea-mediated replication stress and susceptible to oncogene-induced cellular transformation. In addition, Ciz1(-/-) mice developed various types of leukemias by retroviral insertional mutagenesis. These results indicate that CIZ1 functions as a tumor suppressor in vivo.
Risk Factors for Pancreatic Cancer in China: A Multicenter Case-Control Study (2015)

Cigarette smoking, family history, obesity, and diabetes are risk factors of pancreatic cancer, which is important information for designing early intervention and preventive strategies for pancreatic cancer and may be beneficial to pancreatic cancer control in China.
High contrast tumor imaging with radio-labeled antibody Fab fragments tailored for optimized pharmacokinetics via PASylation (2014)

Although antigen-binding fragments (Fabs) of antibodies constitute established tracers for in vivo radiodiagnostics, their functionality is hampered by a very short circulation half-life. PASylation, the genetic fusion with a long, conformationally disordered amino acid chain comprising Pro, Ala and Ser, provides a convenient way to expand protein size and, consequently, retard renal filtration. Humanized αHER2 and αCD20 Fabs were systematically fused with 100 to 600 PAS residues and produced in E. coli. Cytofluorimetric titration analysis on tumor cell lines confirmed that antigen-binding activities of the parental antibodies were retained. The radio-iodinated PASylated Fabs were studied by positron emission tomography (PET) imaging and biodistribution analysis in mouse tumor xenograft models. While the unmodified αHER2 and αCD20 Fabs showed weak tumor uptake (0.8% and 0.2% ID/g, respectively; 24 h p.i.) tumor-associated radioactivity was boosted with increasing PAS length (up to 9 and 26-fold, respectively), approaching an optimum for Fab-PAS400. Remarkably, 6- and 5-fold higher tumor-to-blood ratios compared with the unmodified Fabs were measured in the biodistribution analysis (48 h p.i.) for αHER2 Fab-PAS100 and Fab-PAS200, respectively. These findings were confirmed by PET studies, showing high imaging contrast in line with tumor-to-blood ratios of 12.2 and 5.7 (24 h p.i.) for αHER2 Fab-PAS100 and Fab-PAS200. Even stronger tumor signals were obtained with the corresponding αCD20 Fabs, both in PET imaging and biodistribution analysis, with an uptake of 2.8% ID/g for Fab-PAS100 vs. 0.24% ID/g for the unmodified Fab. Hence, by engineering Fabs via PASylation, plasma half-life can be tailored to significantly improve tracer uptake and tumor contrast, thus optimally matching reagent/target interactions.
Repeat-pass interferometry with airborne synthetic aperture radar (1993)

It is shown that interference can be observed by coherently combining pairs of either X- or C-band airborne synthetic aperture radar (SAR) images from separate passes over the same test site. Coherence between separate images is obtained only if the aircraft is flown, and the data are processed in such a way that each resolution cell in the two images is viewed with very nearly the same geometry. Successful repeat-pass interferometric results were obtained from those passes flown by the CCRS Convair 580 aircraft with flight-line offsets of less than a few tens of meters. A summary of the experiment, the phase correction of nonrectilinear aircraft motion, and the subsequent data processing is provided.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
An 8-b 50-MHz 225-mW submicron CMOS ADC using saturation eliminated comparators (2002)

The fastest, low-power 8-b CMOS subranging A/D converter with a 50-MHz conversion rate and 225-mW power consumption is realized using 0.8- mu m CMOS technology. The comparator used in the converter has a saturation elimination circuit, which eliminates the comparison delay caused by saturation. This circuit is useful for improving conversion speed or reducing converter power consumption. It is also effective in achieving low-power medium-speed converters. An 8-b 20-MHz 65-mW A/D converter can also be achieved with the same circuitry by decreasing the bias current. Therefore, this new converter makes it possible to realize mixed digital-analog ASICs for HDTV and for ED/IDTV applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Model-based iterative reconstruction for magnetic resonance fingerprinting (2015)

Magnetic resonance fingerprinting (MRF) is an emerging quantitative magnetic resonance (MR) imaging technique that simultaneously acquires multiple tissue parameters (e.g., spin density, T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> , and T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ) in an efficient imaging experiment. A statistical estimation framework has recently been proposed for MRF reconstruction. Here we present a new model-based reconstruction method within this framework to enable improved parameter estimation from highly under-sampled, noisy k-space data. It features a novel mathematical formulation that integrates a low-rank image model with the Bloch equation based MR physical model. The proposed formulation results in a nonconvex optimization problem, for which we develop an efficient iterative algorithm based on variable splitting, the alternating direction method of multipliers, and the variable projection method. Representative results from numerical experiments are shown to illustrate the performance of the proposed method.
Learning Guided Convolutional Network for Depth Completion (2019)

Dense depth perception is critical for autonomous driving and other robotics applications. However, modern LiDAR sensors only provide sparse depth measurement. It is thus necessary to complete the sparse LiDAR data, where a synchronized guidance RGB image is often used to facilitate this completion. Many neural networks have been designed for this task. However, they often na\"ıvely fuse the LiDAR data and RGB image information by performing feature concatenation or element-wise addition. Inspired by the guided image filtering, we design a novel guided network to predict kernel weights from the guidance image. These predicted kernels are then applied to extract the depth image features. In this way, our network generates content-dependent and spatially-variant kernels for multi-modal feature fusion. Dynamically generated spatially-variant kernels could lead to prohibitive GPU memory consumption and computation overhead. We further design a convolution factorization to reduce computation and memory consumption. The GPU memory reduction makes it possible for feature fusion to work in multi-stage scheme. We conduct comprehensive experiments to verify our method on real-world outdoor, indoor and synthetic datasets. Our method produces strong results. It outperforms state-of-the-art methods on the NYUv2 dataset and ranks 1st on the KITTI depth completion benchmark at the time of submission. It also presents strong generalization capability under different 3D point densities, various lighting and weather conditions as well as cross-dataset evaluations. The code will be released for reproduction.
GPR56 is highly expressed in neural stem cells but downregulated during differentiation (2009)

The G-protein-coupled receptor 56 (GPR56) plays important roles in brain development and tumorigenesis. cDNA data suggest that GPR56 has potential to become a neural stem cell (NSC) or neural progenitor cell (NPC) marker. However, expression of GPR56 protein in human NSC/NPCs was not explored. Using specific antibodies and immunochemistry, we showed that GPR56 was highly expressed in nestin-positive NSC/NPCs in the ventricular/subventricular zone of human and mouse fetal brains, and in cultured neurospheres derived from both human and mouse fetal brains. Downregulation of GPR56 protein occurred earlier than that of nestin in differentiating neurosphere cultures. Loss of GPR56 protein was also evident in well-differentiated glial fibrillary acidic protein-positive astrocytes and betaIII-tubulin-positive neurons. Our data suggest that GPR56 can be used as an NSC/NPC marker within the neural cell lineage, especially in combination with nestin.
Liquid Crystals of DNA‐Stabilized Carbon Nanotubes (2005)

Water-based liquid crystals of unfunctionalized carbon nanotubes are reported for the first time (see Figure, scale bar: 50 μm). Denatured DNA is used to stabilize the nanotube suspensions. The average length and diameter of the nanotubes are measured using dynamic light scattering. The phase diagram of the system is discussed on the basis of these dimensional characterizations.
Friction on Ice (1988)

Abstract The friction on ice is strongly dependent on temperature. At sufficiently low temperatures, the frictional resistance on ice is high comparable to those on wet or even dry solid surfaces. As temperature rises and approaches the melting point of ice, however, friction rapidly decreases. Differing from the friction of a rubber on ordinary dry or wet solid surfaces the energy loss processes in the rubber do not seem to be the direct source of the frictional resistance on ice. Although frictional melting of ice could occur at high sliding speeds, an ice surface is inherently lubricated with a persistent mobile fluid layer at relatively high temperatures, near the melting point of ice. When a rubber slides on an ice surface, the fluid layer is sheared and undergoes drag flow. The energy loss process necessary for the frictional resistance takes place primarily in the fluid layer, and not in the rubber. The frictional resistance on ice is primarily determined by the viscosity and the thickness of the lubricating fluid layer. What is required of a rubber for better traction under such a condition is that the rubber surface follows the topography of the ice surface as closely as possible, so that more patches of ice surface can be sheared. Therefore, the rubber has to be sufficiently soft to show high friction on ice. Further improvement of the friction could be obtained by making it more resilient. Thus, a rubber with high friction on ice must be compounded so that the polymer chains maintain a high level of mobility at moderately low temperatures. This can be achieved by using polymers with low glass-transition-temperatures. An increased softener loading level helps to improve friction, but to a limited extent. In order to take maximum advantage of softeners, the choice of softener system is important. A relation common to all the mixed softener systems, except the ones containing high-viscosity softeners, was found to exist between the friction on ice and the solubility parameter of the softener mixture in the rubber. The friction on ice was maximized by selecting a softener system with a solubility parameter near that of the polymers in the rubber. The solubility parameter dependence of the friction was consistent with those of softness and resilience.
[Cloning and expression of human GABARAP and preparation of anti-GABARAP antibodies]. (2008)

GABARAP, a microtuble-associated protein, is identified to interact with GABAA receptor. Anchoring of the GABAA receptor to GABARAP helps to cluster the receptor at the synaptic termini and to mediate fast synaptic transmission. GABARAP may mediate interaction of gephyrin with the GABAA receptor to stabilize clusters by forming multimeric structures. Furthermore, GABARAP and gephyrin may play more of a role in receptor sorting and transport to the cell surface than in anchoring to the cytoplasm, because at inhibitory synapses GABARAP appears to associate with transport vesicles rather than the cell surface. The association of GABARAP with NSF (N-ethylmaleimide sensitive factor), a protein involved in intracellular vesicle transport, supports this hypothesis. We cloned cDNA encoding full-length human GABARAP by nested PCR and inserted it into eukaryon expression vector pcDNA6HA and GST fusion protein expression vector pGEX4T2. The recombinant plasmid pGEX4T2-hGABARAP was transformed into E. coli BL21, from which GST-hGABARAP fusion protein was purified after IPTG induction by affinity chromatography with glutathione Sepharose-4B column. The antiserum against GABARAP was generated by immunizing rabbits with the purified GST-hGABARAP and was purified with GST-hGABARAP coupled NHS-activated Sepherose 4 column. The purified polyclonal antibody was effective for Western blotting and immunostaining. The hGABARAP was located both in the cytoplasm and nucleus with an abundant distribution around the peripheral nucleus.
A Review of Mechanical Move Sprinkler Irrigation Control and Automation Technologies (2012)

Electronic sensors, equipment controls, and communication protocols have been developed to meet the growing interest in using center pivot and lateral move irrigation systems to deliver different irrigation depths to management zones based on previous production levels, soil texture, or topography. Onboard and field-distributed sensors can collect data necessary for real-time irrigation management decisions and transmit the information directly or through wireless networks to the main control panel or base computer. Equipment controls necessary to alter water application depth to meet the management criteria for relatively small management zones are now commercially available from irrigation system manufacturers and after-market suppliers. Communication systems such as cell phones, satellite radios, and internet-based systems are also available and allow the operator to query the main control panel or base computer from any location at any time. Selection of the communications system for remote access depends on local and regional topography and cost relative to other methods. Recent developments in the center pivot sprinkler industry have led to contractual relationships between after-market suppliers and irrigation system manufacturers that should support further development of technologies necessary to improve the management of water, nutrient and pesticide applications. Although the primary focus of this article is center pivot sprinkler irrigation, much of the discussion could also apply to lateral move sprinkler irrigation systems.
Comparative Study of the Manufacturing Cost and Productivity of Spiral and Straight Bevel Gear (2013)

The tractor front axle has the lower standard for noise and vibration relatively and it increase the possibility to develop of the alternative straight bevel gear of the expensive spiral bevel gear. The purpose of this paper is to compare of the spiral vs. the straight bevel gear manufacturing process. The manufacturing cost and productivity are compared after the spiral bevel gear of the tractor front axle is replaced of to the straight bevel gear. If spiral bevel gear is replaced to straight bevel gear, the cost is reduce 4.6% and productivity is increase 18%.
Gifts (1987)

A gift, according to the Concise Oxford Dictionary, is a ‘voluntary transference of property; thing given, present, donation’. For most economists, especially those familiar only with industrial capitalist economies, this is all that need be said on the matter: it is obvious what gift exchange is and there is nothing to be explained. The only problem the phenomenon of exchange poses for the economist is that of ‘value’ and this arises in the context of commodity exchange.
Noninflammatory phagocytosis of monosodium urate monohydrate crystals by mouse macrophages: Implications for the control of joint inflammation in gout (2000)

We demonstrated that phagocytosis and TNFalpha production are distinct events in the response of mononuclear phagocytes to urate crystals, and these events can be distinguished at the level of macrophage differentiation. The noninflammatory removal of urate crystals by mature macrophages defines a new pathway that may be important in controlling the development of acute gout in patients with hyperuricemia.
Combining Authentication with Role-Based Access Control Based on IBS (2006)

Authentication and access control are crucial for information and system security. In this paper, we present a scheme to cryptographically provide authentication and role-based access control (RBAC) for large organizations using identity-based signature (IBS) technique. To achieve this, we first extend the elements user and role in RBAC model to cooperate with identity-based cryptography. Our scheme is derived from Cha-Cheon's identity-based signature scheme based on bilinear pairings. In our scheme, both user authentication and role-based authorization can be verified simultaneously by a user's signature, so the independent authentication procedure is eliminated. We also prove the security of the proposed scheme against adaptively chosen message and ID attack under the random oracle model
Flat-top mode from a 50 µm-core Yb-doped leakage channel fiber (2013)

We demonstrate for the first time a flat-top mode from a 50 µm-core Yb-doped leakage channel fiber (LCF). The flat intensity distribution leads to an effective mode area of ~1880 µm(2) in the straight fiber, an over 50% increase comparing to that of regular LCF with the same core diameter. The flat-top mode was achieved by using a uniform Yb-doped silica glass in the core center with an index of ~2 × 10(-4) lower than that of the silica background. The fiber was also tested in a laser configuration, demonstrating an optical-to-optical efficiency of ~77% at 1026 nm with respect to the pump at 975 nm.
Convolutional recurrent neural networks: Learning spatial dependencies for image representation (2015)

In existing convolutional neural networks (CNNs), both convolution and pooling are locally performed for image regions separately, no contextual dependencies between different image regions have been taken into consideration. Such dependencies represent useful spatial structure information in images. Whereas recurrent neural networks (RNNs) are designed for learning contextual dependencies among sequential data by using the recurrent (feedback) connections. In this work, we propose the convolutional recurrent neural network (C-RNN), which learns the spatial dependencies between image regions to enhance the discriminative power of image representation. The C-RNN is trained in an end-to-end manner from raw pixel images. CNN layers are firstly processed to generate middle level features. RNN layer is then learned to encode spatial dependencies. The C-RNN can learn better image representation, especially for images with obvious spatial contextual dependencies. Our method achieves competitive performance on ILSVRC 2012, SUN 397, and MIT indoor.
[Synthesis and biological activity of 1,2,3-triazol-1,8-naphthyridines]. (1976)

The reaction of 2-methyl-5-azido-1,8-naphthyridine with active methylene compounds was investigated. Several naphthyridines which possess the 1,2,3-triazole ring as a substituent were obtained. Among these compounds (IV o) showed an analgesic activity twice that of phenylbutazone.
Role of sulfated glycoprotein‐1 (SGP‐1) in the disposal of residual bodies by sertoli cells of the rat (1995)

Sulfated glycoprotein-1 (SGP-1) is a polypeptide secreted by Sertoli cells in the rat. Sequence analysis revealed a 76% sequence similarity with human prosaposin produced by various cell types. Human prosaposin is a 70 kDa protein which is cleaved in the lysosomes into four 10-15 kDa polypeptides termed saposins A, B, C, and D. The function of lysosomal saposins is to either solubilize certain membrane glycolipids or to form complexes with lysosomal enzymes and/or their glycolipid substrate to facilitate their hydrolysis. The present investigation dealt with the delivery of SGP-1 into the phagosomes of Sertoli cells; these phagosomes contain the residual bodies which detach from the late spermatids at the time of spermiation. Immunogold labeling with anti-SGP-1 antibody was found over Sertoli cell lysosomes, but was absent from phagosomes formed after phagocytosis of spermatid residual bodies in the apical Sertoli cell cytoplasm in stages VIII and early IX of the cycle of the seminiferous epithelium. The phagosomes found later in the basal Sertoli cell cytoplasm in stages IX and X of the cycle became labeled with the antibody as the components of the residual bodies rapidly underwent lysis and disappeared from the Sertoli cells. Sertoli cell lysosomes isolated by cell fractionation (estimated purity of 80%) were found to contain a 65 kDa form of SGP-1 or prosaposin, as well as the 15 kDa polypeptides or saposins. Thus, it appears that this unique lysosomal form of SGP-1 reached the Sertoli cell phagosomes and that their derived polypeptides, the saposins, must play a role in the hydrolysis of membrane glycolipids found in phagocytosed residual bodies.