gebhart/patrepeval huggingface dataset:
An Open-label Study of Memantine Treatment in 3 Subtypes of Frontotemporal Lobar Degeneration (2009)

There are currently no Food and Drug Administration-approved treatments for frontotemporal lobar degeneration (FTLD). The objectives of this study were to explore the tolerability of memantine treatment in FTLD and to monitor for possible effects on behavior, cognition, and function. Forty-three individuals who met clinical criteria for FTLD [21 with frontotemporal dementia (FTD), 13 with semantic dementia (SD), and 9 with progressive nonfluent aphasia (PA)] received 26 weeks of open-label treatment with memantine at a target dose of 20 mg daily. Concurrent treatment with acetylcholinesterase inhibitors was prohibited. Cognitive and functional outcome measures included the Mini Mental State Examination, Alzheimer's Disease Assessment Scale-Cognitive (ADAS-cog), clinical dementia rating-sum of boxes, Neuropsychiatric Inventory (NPI), Frontal Behavior Inventory, Executive Interview (EXIT25), Texas Functional Living Scale (TFLS), Geriatric Depression Scale, and Unified Parkinson's Disease Rating Scale-motor scale. Most subjects were able to tolerate the target dose of memantine. A transient improvement was observed on the total NPI score primarily in the FTD group. Variable declines were observed on the ADAS-cog, EXIT25, Frontal Behavior Inventory, NPI, TFLS, and UPDRS scores. The FTD and SD groups declined on most of the cognitive and behavioral outcome measures, but remained stable on the UPDRS, whereas the progressive nonfluent aphasia group remained relatively stable on the ADAS-cog, NPI, and TFLS, but declined on the UPDRS. Memantine was well-tolerated in these subjects. Future placebo-controlled trials of memantine in FTLD are warranted and may have greater power to detect behavioral and cognitive effects if focused on the FTD and SD clinical syndromes.
Age‐related differences in absolute numbers of skeletal muscle satellite cells (1983)

The absolute number of satellite cells (SC) in young and adult rat skeletal muscle was estimated by correlating data from light and electron microscopic quantitation of myofiber nuclei (myonuclei and satellite cell nuclei) with biochemical assays for determining total muscle DNA content. Expressed both as a proportion of total myofiber nuclei and as absolute numbers, satellite cells are more numerous in the predominantly oxidative soleus muscle than in the mixed glycolytic/oxidative extensor digitorum longus (EDL) muscle at 1, 12, and 24 months of age. Satellite cell proportions decline gradually in both muscles with advancing age, but absolute numbers increase significantly in the soleus between 1 and 12 months, while EDL exhibits a continuous significant decline in satellite cells between each of the ages examined.
Comparative analysis of IEEE 802.1x authentication methods (2007)

Abstract:- The IEEE Standard 802.11 is one of the most widely adopted mechanisms for WLANs, it provides comprehensive guidelines for their operational smoothness. 802.11 suffered from limited data confidentiality and cumbersome procedure for exchange of security parameters. In response to the security limitations in 802.11, IEEE introduced 802.1x for authentication and key management. The 802.1x is a port based network access control protocol that uses Extensible Authentication Protocol (EAP) at the transport layer. The 802.1x only defines authentication mechanism and does not recommend any appropriate authentication method. Consequently wireless vendors implemented their own 802.1x adaptations such as MD5 (Message Digest 5),
CsSnI<sub>3</sub>: Semiconductor or Metal? High Electrical Conductivity and Strong Near-Infrared Photoluminescence from a Single Material. High Hole Mobility and Phase-Transitions (2012)

CsSnI(3) is an unusual perovskite that undergoes complex displacive and reconstructive phase transitions and exhibits near-infrared emission at room temperature. Experimental and theoretical studies of CsSnI(3) have been limited by the lack of detailed crystal structure characterization and chemical instability. Here we describe the synthesis of pure polymorphic crystals, the preparation of large crack-/bubble-free ingots, the refined single-crystal structures, and temperature-dependent charge transport and optical properties of CsSnI(3), coupled with ab initio first-principles density functional theory (DFT) calculations. In situ temperature-dependent single-crystal and synchrotron powder X-ray diffraction studies reveal the origin of polymorphous phase transitions of CsSnI(3). The black orthorhombic form of CsSnI(3) demonstrates one of the largest volumetric thermal expansion coefficients for inorganic solids. Electrical conductivity, Hall effect, and thermopower measurements on it show p-type metallic behavior with low carrier density, despite the optical band gap of 1.3 eV. Hall effect measurements of the black orthorhombic perovskite phase of CsSnI(3) indicate that it is a p-type direct band gap semiconductor with carrier concentration at room temperature of ∼ 10(17) cm(-3) and a hole mobility of ∼585 cm(2) V(-1) s(-1). The hole mobility is one of the highest observed among p-type semiconductors with comparable band gaps. Its powders exhibit a strong room-temperature near-IR emission spectrum at 950 nm. Remarkably, the values of the electrical conductivity and photoluminescence intensity increase with heat treatment. The DFT calculations show that the screened-exchange local density approximation-derived band gap agrees well with the experimentally measured band gap. Calculations of the formation energy of defects strongly suggest that the electrical and light emission properties possibly result from Sn defects in the crystal structure, which arise intrinsically. Thus, although stoichiometric CsSnI(3) is a semiconductor, the material is prone to intrinsic defects associated with Sn vacancies. This creates highly mobile holes which cause the materials to appear metallic.
YBa2Cu3O7−<i>x</i> films on flexible, partially stabilized zirconia substrates with fully stabilized zirconia buffer layers (1991)

Textured polycrystalline YBCO films with superconducting transition temperatures of ∼90 K have been prepared on flexible zirconia substrates, partially stabilized by 3 mol % yttria. X-ray data suggest undesirable (013) and [(110) (103)] texture in minor amounts within the predominantly c-axis oriented film. The transmission electron microscope data reveal clean, special crystallographic as well as silicon contaminated grain boundaries containing amorphous phases. By depositing a zirconia buffer layer, fully stabilized by 9 mol % yttria, we have demonstrated that the normal-state metallic and superconducting properties of the YBCO films can be considerably improved. These films exhibit critical-current densities of ∼0.9×104 A/cm2 at 77 K in zero field and 2×105 A/cm2 at 4.2 K in zero field.
Review of Polarized Proton Beam Acceleration at KEK-PS in the 1980’s (2003)

A polarized proton beam was accelerated at the KEK‐PS in the late 1980’s. This report will review the activities for the polarized beam acceleration in both the 500 MeV booster and the 12 GeV Main Ring. Some depolarization resonances were passed using the spin‐flip techniques. The effects on the polarization caused by a synchrotron side‐band at a strong intrinsic resonance were observed.
O RISCO DE EROS NA PELE DO TEXTO: A POESIA ERÓTICO-CONCRETA DE DÉCIO PIGNATARI (2018)

Considerado a ultima vertente das vanguardas, o concretismo foi um movimento que surgiu na decada de 1950, em Sao Paulo, especificamente da triade formada pelos irmaos Augusto e Haroldo de Campos, e Decio Pignatari. Por cerca de tres decadas o movimento produziu textos cuja concretude se dava pela valorizacao da palavra em sua forma tipografica disposta na geografia do papel. Herdeira de Mallarme, Apollinaire, Joyce, Cummings e Oswald de Andrade, a poesia concreta tornou-se produto de exportacao, aquilo com o qual havia sonhado Oswald de Andrade. O concretismo foi o campo onde a tradicao literaria ocidental e oriental seria atualizada, traduzida, “transcriada”, sintetizada em imagens, tipos, formas, num entrecruzamento de discursos. Os temas dessa poesia atualizam alguns problemas humanos recorrentes na literatura. Um desses temas e o erotismo, em suas diversas ramificacoes, ora de cunho classico, ora de cunho profanatorio ou carnavalizado. Portanto, o artigo se propoe a analisar a poesia concreta erotica de Decio Pignatari, procurando investigar sua relacao com o discurso erotico do Ocidente e do Oriente. Alem disso, procurou-se interpretar esses poemas a luz dos teoricos do erotismo, tais como Freud, Bataille, Barthes, Octavio Paz e Foucault.
Comparing the Power of Full Disk Encryption Alternatives (2012)

This paper examines the energy costs of different approaches to full disk encryption, including hardware encryption, software encryption, and "no encryption". Using the DEEP power measurement platform, we measured the energy consumed by each configuration under various workloads. We demonstrate that hardware encryption saves energy for many (though not all) workloads, but that the energy savings may not compensate for the hardware price at current rates.
Altered Phase Precession and Compression of Temporal Sequences by Place Cells in Epileptic Rats (2008)

In the hippocampus, pyramidal cells encode information in two major ways: rate coding and temporal coding. Rate coding, in which information is coded through firing frequency, is exemplarily illustrated by place cells, characterized by their location-specific firing. In addition, the precise temporal organization of firing of multiple place cells provides information, in a compressed time window, about the temporal sequence of the locations visited by the animal. This encoding is accomplished through phase precession, a phenomenon whereby unit firing is linked to theta rhythm, one of the major hippocampal EEG oscillations. Although it is likely that this type of processing is critical for normal brain function, its involvement in pathologies associated with cognitive disorders is unknown. In this experiment, we determined whether the temporal organization of place cell firing is affected in an animal model of mesial temporal lobe epilepsy (MTLE), a disease accompanied with cognitive impairment. We investigated hippocampal coding and its relationship to theta rhythm in rats after status epilepticus (SE), a condition that leads to MTLE. We found a great proportion of SE place cells had aberrant phase/precession pattern and temporal organization of firing among pairs of neurons, which constitutes the compression of temporal sequences, was altered in SE rats. The same animals were also markedly impaired in the water maze task, a measure of spatial memory. We propose that the synaptic and cellular alterations observed in MTLE induce aberrant temporal coding in the hippocampus, contributing in turn to cognitive dysfunction.
Dynamic load balancing for parallel volume rendering (2006)

Parallel volume rendering is one of the most efficient techniques to achieve real time visualization of large datasets by distributing the data and the rendering process over a cluster of machines. However, when using level of detail techniques or when zooming on parts of the datasets, load unbalance becomes a challenging issue that has not been widely studied in the context of hardware-based rendering. In this paper, we address this issue and show how to achieve good load balancing for parallel level of detail volume rendering. We do so by dynamically distributing the data among the rendering nodes according to the load of the previous frame. We illustrate the efficiency of our technique on large datasets.
Molecular-beam epitaxy (MBE) of In1−<i>x</i>Ga<i>x</i>As and GaSb1−<i>y</i>As<i>y</i> (1977)

Films of In1−xGaxAs and GaSb1−yAsy over the entire composition ranges have been grown on (100) GaAs, InAs, and GaSb substrates by MBE. In situ observations by high-energy electron diffraction have revealed a variety of surface reconstructions and correlated the growth process with the lattice mismatch. The compositions are governed by the relative rates of In and Ga in In1−xGaxAs, but primarily by that of Sb in GaSb1−yAsy because of its dominant incorporation over As. In these alloys, Sn is found to be a donor throughout In1−xGaxAs but an amphoteric impurity in GaSb1−yAsy.
Specifications for the development of an expert tool for the automatic optical understanding of electronic circuits: VLSI reverse engineering (2002)

Deals with the specifications for the development of an expert tool for the automatic optical detection and recognition of the connectivity among devices in digital electronic circuits and the understanding of the circuits functionality. In particular, the proposed tool, called ANTISTROFEAS, uses expert knowledge recognizing and understanding electronic circuits without the use of their associated database. The ANTISTROFEAS tool will use classical picture processing methods in combination with heuristics and knowledge acquisition schemes. The expert tool proposed is used for understanding of 'unknown' electronic circuits, or where the complexity of the circuit is too great, so that any human searching effort requires long time for reliable results.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Successful Use Of The Borehole Gravity Meter In Northern Michigan (1975)

Borehole gravity surveys have been used in Northern Michigan to make producers out of otherwise dry holes. Wells which are drilled in thick, tight, salt-plugged reefs may have encountered a very restricted, tight facies. The borehole gravity survey can be used to detect nearby porosity. Such porosity zones can be entry beds to the main reservoir. The basis for qualitative interpretation is to determine the sidewall lithology and then evaluate which rock parameters could vary laterally to change bulk density. Porosity changes produce distinct low density deflections on gravity log plots. The bases for quantitative evaluations are the results of computer models or of simple cylindrical models. The maximum distance to a porous zone can be calculated using a cylindrical or ring-shaped model.
Statistical model for power plant performance monitoring and analysis (2007)

A novel approach for monitoring and analysing power plant operation and performance is presented utilizing statistical modelling technology, specifically linear partial least squares (PLS) and non-linear radial basis function (RBF-PLS) models. For the RBF neural network, a genetic algorithm (GA) is employed to optimise the model parameters. The potential of these models for signal and error prediction, and performance analysis is demonstrated utilizing data from a combined cycle gas turbine (CCGT).
The role of the fetal fibroblast and transforming growth factor-beta in a model of human fetal wound repair. (1996)

The fetus heals skin wounds without scar formation. Human fetal skin that is transplanted to a subcutaneous location on an adult athymic mouse and subsequently wounded heals without scar formation, whereas the same fetal skin heals with scar formation when transplanted to a cutaneous location. To characterize the healing process of human fetal skin in these two locations, species-specific human and mouse DNA probes were constructed and used to probe graft wounds under high stringency in situ hybridization conditions. Immunostaining for species-specific fibroblasts, macrophages, and neutrophils was also performed. The cutaneous human fetal graft healed with scar and showed an influx of adult mouse fibroblasts and macrophages. In contrast, subcutaneous human fetal grafts showed exclusively human fetal fibroblasts in the wound environment, an absence of inflammatory cells, and scar-free repair. Thus, the highly organized collagen deposition in scarless human fetal wound repair appears to be intrinsic to the human fetal fibroblast and occurs in the absence of an adult-like inflammatory response. One important cytokine involved in wound repair is transforming growth factor-beta (TGF beta). TGF beta promotes inflammatory cell recruitment and collagen deposition in healing wounds. To determine the role of TGF beta 1 in fetal wound healing, in situ hybridization for TGF beta 1 mRNA expression, immunostaining for TGF beta protein, and species-specific immunohistochemistry for fibroblasts, macrophages, and neutrophils were performed in human adult wounds, fetal wounds, and fetal wounds treated with a TGF beta 1 slow release disk. TGF beta 1 RNA expression and TGF beta protein were found in wounded adult skin. Neither TGF beta 1 mRNA upregulation nor TGF beta protein was detected in human fetal skin after wounding. However, when exogenous TGF beta 1 was added to human fetal skin, induction of TGF beta 1 mRNA expression in human fetal fibroblasts occurred, an adult-like inflammatory response was detected, and the skin healed with scar formation. Thus, non-scarring fetal skin is relatively TGF beta 1 deficient when compared to scarring adult skin. Furthermore, when exogenous TGF beta is added to fetal skin, scarring occurs. TGF beta appears to be an important modulator in scar formation. With a more thorough understanding of scarless repair mechanisms, clinical induction of scarless healing in adults and children soon may be possible.
ChemInform Abstract: Metal Complexes in Organic Synthesis. Preparation of α‐(1‐Adamantyl)‐β‐dicarbonyl Compounds and 4‐(1‐Adamantyl)‐3,5‐disubstituted Pyrazoles and Isoxazoles. (1986)

Abstract Adamantyl substituted heterocycles have anticancer and antiviral properties.
Photosensitization of Onium Salt Initiated Cationic Photopolymerizations by Carbazole Monomers, Polymers, and Oligomers (2003)

Carbazole compounds are efficient electron-transfer photosensitizers for onium salt photoinitiated cationic polymerizations of vinyl and heterocyclic monomers. Oligomers and polymers containing carbazole groups are especially attractive as photosensitizers. Copolymers of N-vinylcarbazole (NVK) with vinyl monomers and a dimeric photosensitizer were also synthesized and shown to be efficient onium salt photosensitizers.
Identification of Amino Acids in the N‐Terminal Domain of Corticotropin‐Releasing Factor Receptor 1 that Are Important Determinants of High‐Affinity Ligand Binding (1999)

The aim of the present study was to identify the N-terminal regions of human corticotropin-releasing factor (CRF) receptor type 1 (hCRF-R1) that are crucial for ligand binding. Mutant receptors were constructed by replacing specific residues in hCRF-R1 with amino acids from the corresponding position in the N-terminal region of the human vasoactive intestinal peptide receptor type 2 (hVIP-R2). In cyclic AMP stimulation and CRF binding assays, it was established that two regions within the N-terminal domain were crucial for the binding of CRF receptor agonists and antagonists: one region mapping to amino acids 43-50 and a second amino acid sequence extending from position 76 to 84 of hCRF-R1. Recently, it was found that the latter sequence plays a very important role in determining the high ligand selectivity of the Xenopus CRF-R1 (xCRF-R1). Replacement of amino acids 76-84 of hCRF-R1 with residues from the same segment of the hVIP-R2 N terminus markedly reduced the binding affinity of CRF ligands. Mutation of Arg76 or Asn81 but not Gly83 of hCRF-R1 to the corresponding amino acids of xCRF-R1 or hVIP-R2 resulted in 100-1,000-fold lower affinities for human/rat CRF, rat urocortin, and astressin. These data underline the importance of the N-terminal domain of CRF-R1 in high-affinity ligand binding.
A benchmark of NonStop SQL release 2 demonstrating near-linear speedup and scaleup on large databases (1990)

No abstract available.
A Next–Generation Isobaric Energy Recovery Device (2015)

An energy recovery device has an important role in reducing specific energy consumption in seawater reverse osmosis desalination process. A next–generation isobaric energy recovery device (ERD) has been developed under the Mega–ton Water System Project. The device achieved 2% higher energy recovery effectiveness and low volumetric mixing without over–flush compared to the conventional ERD. The design concept and its characteristic feature of the next–generation ERD is presented together with the results of experimental validation and numerical computations.
Hysteresis compensation of piezoelectric actuators in dual-stage Hard Disk Drives (2011)

ASCC 2011 - 8th Asian Control Conference - Final Program and Proceedings
The genetic algorithm and biological development (1987)

The arbitrarily primed-PCR (AP-PCR) genomic fingerprinting method was applied to evaluate its effectiveness in detecting and characterizing amplified DNA fragments in two small-cell lung carcinoma (SCLC) cell lines, NCI-H69 and NCI-H82. Of the 2428 DNA fragments detected by AP-PCR using 62 arbitrary primers, 2 (0.08%) DNA fragments were amplified in NCI-H69 and 6 (0.25%) DNA fragments were amplified in NCI-H82. Based on these results, we estimate the total size of the amplified genomic regions in these cell lines to be 3000 megabase pairs (Mb) x 0.0008 = 2.4 Mb in NCI-H69 and 3000 Mb x 0.0025 = 7.5 Mb in NCI-H82. The 2 amplified fragments in NCI-H69 were mapped to chromosome 2, and all 6 amplified fragments in NCI-H82 were mapped to chromosome 8. This strongly suggests that restricted chromosomal regions are specifically amplified in these SCLC cell lines. Since the N-myc gene at 2p24 is amplified in NCI-H69 and the c-myc gene at 8q24 is amplified in NCI-H82, it is possible that these DNA fragments are co-amplified with N-myc or c-myc in these cell lines. However, since the 2 amplified fragments in NCI-H69 were not amplified in 42 other human cancer cell lines including 11 cell lines carrying amplified N-myc genes, it is also possible that there are amplified regions on chromosome 2 other than the N-myc locus at 2p24 in NCI-H69. In contrast, all 6 amplified fragments in NCI-H82 were amplified in several other human cancer cell lines carrying amplified c-myc genes. This result further indicates that these fragments were derived from an amplification unit that includes the c-myc gene. Our results show the ability of the AP-PCR method to analyze the fraction of the genome with amplification in human cancer cells.
Enhancing the Functionality of Interactive TV with Content-Based Multimedia Analysis (2009)

In this paper we describe how content-based analysis techniques can be used to provide much greater functionality to the users of an interactive TV (iTV) device. We describe several content-based multimedia analysis techniques and how some of these can be exploited in the iTV domain, resulting in the provision of a set of powerful functions for iTV users. To validate our ideas, we introduce an iTV application we developed which incorporates some of these techniques into a simple set of user features, in order to demonstrate the usefulness of content-based techniques for iTV. The contribution of this paper is not to provide an in-depth discussion on each of the individual content-based techniques, but rather to show how many of these powerful technologies can be incorporated into an interactive TV system.
Cascaded Authorization with Anonymous-Signer Aggregate Signatures (2006)

We introduce a decentralized trust management model called anonymous role-based cascaded delegation. In this model, a delegator can issue authorizations on behalf of her role without revealing her identity. This type of delegation protects the sensitive membership information of a delegator and hides the internal structure of an organization. To provide an efficient storage and transmission mechanism for credentials used in anonymous role-based cascaded delegation, we present a new signature scheme that supports both signer anonymity and signature aggregation. Our scheme has compact role signatures that make it especially suitable for ubiquitous computing environments, where users may have mobile computing devices with narrow communication bandwidth and small storage units