gebhart/patrepeval huggingface dataset:
Mucormycosis Caused by Unusual Mucormycetes, Non-Rhizopus, -Mucor, and -Lichtheimia Species (2011)

Rhizopus, Mucor, and Lichtheimia (formerly Absidia) species are the most common members of the order Mucorales that cause mucormycosis, accounting for 70 to 80% of all cases. In contrast, Cunninghamella, Apophysomyces, Saksenaea, Rhizomucor, Cokeromyces, Actinomucor, and Syncephalastrum species individually are responsible for fewer than 1 to 5% of reported cases of mucormycosis. In this review, we provide an overview of the epidemiology, clinical manifestations, diagnosis of, treatment of, and prognosis for unusual Mucormycetes infections (non-Rhizopus, -Mucor, and -Lichtheimia species). The infections caused by these less frequent members of the order Mucorales frequently differ in their epidemiology, geographic distribution, and disease manifestations. Cunninghamella bertholletiae and Rhizomucor pusillus affect primarily immunocompromised hosts, mostly resulting from spore inhalation, causing pulmonary and disseminated infections with high mortality rates. R. pusillus infections are nosocomial or health care related in a large proportion of cases. While Apophysomyces elegans and Saksenaea vasiformis are occasionally responsible for infections in immunocompromised individuals, most cases are encountered in immunocompetent individuals as a result of trauma, leading to soft tissue infections with relatively low mortality rates. Increased knowledge of the epidemiology and clinical presentations of these unusual Mucormycetes infections may improve early diagnosis and treatment.
[Malate dehydrogenase and its isoenzymes in the peripheral blood leukocytes in progressive muscular dystrophy of the Duchenne type]. (1985)

The authors studied the composition of isoenzymes of malic dehydrogenase in peripheral blood leucocytes of patients with Duchenne-type progressive muscular dystrophy, their mothers and sisters, and also in other primary muscular diseases. The studied group included 25 patients with Duchenne dystrophy, 20 their mothers and sisters, and 11 patients with other primary muscular diseases. The control group comprised 10 healthy subjects aged 19-40 years. Sporadically a decrease was observed of total activity and of the amount of the mitochondrial isoenzyme of MDH in Duchenne dystrophy. In one case the m-MDH isoenzyme was completely absent, this patient had most advanced disease. In the mothers of patients decreased MDH activity occurred rarely (once in 13 mothers) and the pattern of MDH isoenzymes was normal, similarly as in sisters of these patients. In other primary muscular diseases no abnormalities were found.
High-bandwidth HDD tracking servo by a moving-slider micro-actuator (1999)

This paper describes a micro-actuator for high-bandwidth tracking servo, where a micro-actuator is attached between slider and suspension, and moves the slider relative to the suspension. The micro-actuator frequency response measurement proved that this micro-actuator can be modeled as an ideal spring-mass-damper system up to 80 kHz, so that very high bandwidth servo system can be easily designed. The maximum servo bandwidth of 6.4 kHz was achieved in a drive level experiment, which is the highest bandwidth ever demonstrated as a drive level. A rapid step response time of 0.2 mS for 0.6 /spl mu/m step was also achieved. The experimental bandwidth was not limited by the micro-actuator's resonance mode, but the saturation of the micro-actuator driver.
Preparation and Properties of Boron Nitride Films by Metal Organic Chemical Vapor Deposition (1986)

Boron nitride films have been deposited by a metal organic chemical vapor deposition (MO‐CVD). The reaction between ammonia and triethylboron is carried out in the temperature range of 750°–1200°C with the molar ratio of . Colorless and transparent films are obtained at temperatures of 950°–1100°C with the molar ratio of 20–70. The composition of the films, N/B, is found to vary from 0.46 to 1.0. For a fixed , the deposition rate increases with temperature up to 1000°C and then decreases. The deposition rate shows an Arrhenius‐type behavior in the temperature range of 750°–1000°C. X‐ray diffraction studies indicate that the crystal structure of the films is hexagonal. The energy of the direct allowed transition, obtained from optical measurements, is estimated to be 5.90 eV.
SPIKE: a database of highly curated human signaling pathways (2010)

The rapid accumulation of knowledge on biological signaling pathways and their regulatory mechanisms has highlighted the need for specific repositories that can store, organize and allow retrieval of pathway information in a way that will be useful for the research community. SPIKE (Signaling Pathways Integrated Knowledge Engine; http://www.cs.tau.ac.il/&~spike/) is a database for achieving this goal, containing highly curated interactions for particular human pathways, along with literature-referenced information on the nature of each interaction. To make database population and pathway comprehension straightforward, a simple yet informative data model is used, and pathways are laid out as maps that reflect the curator’s understanding and make the utilization of the pathways easy. The database currently focuses primarily on pathways describing DNA damage response, cell cycle, programmed cell death and hearing related pathways. Pathways are regularly updated, and additional pathways are gradually added. The complete database and the individual maps are freely exportable in several formats. The database is accompanied by a stand-alone software tool for analysis and dynamic visualization of pathways.
Becquerel Photovoltaic Effect in Binary Compounds (1960)

An experimental study has been made of photovoltaic effects which occur at semiconductor-electrolyte interfaces. Single crystal specimens of CdS and several other compounds were used. It was found that in a number of cases the photovoltaic effect results from a chemical reaction of the electrode materials. In such cases the observations may be explained by a simple mechanism which relates the sign of the photo-emf to the conductivity type of the semiconductor and to the chemical reaction which is occurring. The reaction may be predicted using readily available thermodynamic data. A different process occurs when the electrode material is GaAs. It acts as an inert electrode which exchanges electrons with an oxidation-reduction couple in the solution.
A Self-organized Public-Key Certificate System in P2P network (2011)

P2P network is open, anonymous and dynamical in contrast with conventional network. It’s full of dishonesty, deceit, selfishness. It’s necessary to build a robust security infrastructure system.  The one important module of security infrastructure is to identify the users in transactions. This paper will propose an identification solution based on PKI. In our algorithm, the peer generates their public-private key pairs by themselves, issues certificates, and performs authentication without any centralized services. It can realize the identification, meanwhile keep peers anonymous. Moreover, it can limit the quantity of ID that a user applies for; alleviate the risk of Sybil attack.
Phytochemical Analysis of the Essential Oil from Botanically Certified Oleogum Resin of Boswellia sacra (Omani Luban) (2008)

The yield of hydrodistillation of a botanically certified Oleogum Resin of Boswellia sacra essential oil (5.5%); and its chemical constituents were determined. The GC/MS technique was used for the analysis of the oil. Several oil components were identified based upon comparison of their mass spectral data with those of reference compounds published in literature or stored in a computer library. The oil was characterized by the high content of the monoterpenes (34) which constituted 97.3% in which E-beta-ocimene and limonene were the major constituents. The remaining 2.7% was accounted for the sesquiterpenes (16) in which the E-caryophyllene was the major constituent. The analysis proved the complete absence of the diterpenes.
New selective reducing agents (1961)

ADVERTISEMENT RETURN TO ISSUEPREVReportNEXTNew selective reducing agentsHerbert C. Brown Cite this: J. Chem. Educ. 1961, 38, 4, 173Publication Date (Print):April 1, 1961Publication History Received3 August 2009Published online1 April 1961Published inissue 1 April 1961https://doi.org/10.1021/ed038p173RIGHTS & PERMISSIONSArticle Views660Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (5 MB) Get e-Alerts Get e-Alerts
Polyphenol interactions. Part 1. Introduction; some observations on the reversible complexation of polyphenols with proteins and polysaccharides (1985)

Early studies of the interactions between polyphenols and proteins are reviewed. The complexation of some simple phenols and a group of biosynthetically inter-related esters of gallic acid with bovine serum albumin (BSA) is examined by equilibrium dialysis and microcalorimetry. The phenomenon is pH dependent. The results indicate that molecular size and conformational flexibility of the polyphenol substrate lead to enhanced interactions with the protein. Preliminary studies with polysaccharides indicate that the binding here is pH independent. These studies suggest that whilst the binding of polyphenols to these macromolecules is influenced by similar structural features the ability of the polysaccharide to form structures which encapsulate the polyphenol is, in this instance, a further critical feature of the complexation.
Taxonomía tonal en español (2000)

Prenuclear pitch accents (primitives of prominence intonation by the association of H(igh) and L(ow) to segments), and tonal synchronization patterns, the relationship between the duration of the accented syllable and the peak timing, have been analyzed. Three laboratory corpora and two materials of spontaneous speech have been acoustically examined. Pitch accents are classified according to micro-spaces determined by psychophonetic differences, the tonal threshold in each accent rules the opposition H versus L. Results indicate higher frequency of pitch accents H*, H* + L and L + H*, and lower and asystematic correlation between accented syllable duration and peak timing. Findings do not support the view that prenuclear pitch accents in Hispanic dialects are constant, an occurrence of L* + H due to overshooting, but the presence of tonal variation.
Gait transition and modulation in a quadruped robot: A brainstem-like modulation approach (2011)

In this article, we propose a bio-inspired architecture for a quadruped robot that is able to initiate/stop locomotion; generate different gaits, and to easily select and switch between the different gaits according to the speed and/or the behavioral context. This improves the robot stability and smoothness while locomoting. We apply nonlinear oscillators to model Central Pattern Generators (CPGs). These generate the rhythmic locomotor movements for a quadruped robot. The generated trajectories are modulated by a tonic signal, that encodes the required activity and/or modulation. This drive signal strength is mapped onto sets of CPG parameters. By increasing the drive signal, locomotion can be elicited and velocity increased while switching to the appropriate gaits. This drive signal can be specified according to sensory information or set a priori. The system is implemented in a simulated and real AIBO robot. Results demonstrate the adequacy of the architecture to generate and modulate the required coordinated trajectories according to a velocity increase; and to smoothly and easily switch among the different motor behaviors.
PHOTOCHEMICAL REACTIONS OF KETONES IN SOLUTION (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPHOTOCHEMICAL REACTIONS OF KETONES IN SOLUTIONN. C. Yang and Ding-Djung H. YangCite this: J. Am. Chem. Soc. 1958, 80, 11, 2913–2914Publication Date (Print):June 1, 1958Publication History Published online1 May 2002Published inissue 1 June 1958https://pubs.acs.org/doi/10.1021/ja01544a092https://doi.org/10.1021/ja01544a092research-articleACS PublicationsRequest reuse permissionsArticle Views2011Altmetric-Citations204LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Optimization of Liquid-Handling Precision with Neptune Software on a Tecan Genesis (2002)

The process of optimizing the precision of robotic liquid-handling instruments can be improved using the Design of Experiments methodology. Design of Experiments (DOE) is “a collection of statistic...
Transcriptional Regulation of Apolipoprotein C-III Gene Expression by the Orphan Nuclear Receptor RORα (2001)

Triglyceride-rich remnant lipoproteins are considered as major risk factors contributing to the pathogenesis of atherosclerosis. Because apolipoprotein (apo) C-III is a major determinant of plasma triglyceride and remnant lipoprotein metabolism, it is important to understand how the expression of this gene is regulated. In the present study, we identified the orphan nuclear receptor RORalpha1 as a regulator of human and mouse apo C-III gene expression. Plasma triglyceride and apo C-III protein concentrations in staggerer (sg/sg) mice, homozygous for a deletion in the RORalpha gene, were significantly lower than in wild type littermates. The lowered plasma apo C-III levels were associated with reduced apo C-III mRNA levels in liver and intestine of sg/sg mice. Transient transfection experiments in human hepatoma HepG2, human colonic CaCO2, and rabbit kidney RK13 cells demonstrated that overexpression of the human RORalpha1 isoform specifically increases human apo C-III promoter activity, indicating that RORalpha1 enhances human apo C-III gene transcription. RORalpha1 response elements were mapped by promoter deletion analysis and gel shift experiments to two AGGTCA half-sites located at positions -83/-78 (within the C3P site) and -23/-18 (downstream of the TATA box) in the human apo C-III promoter, with the -23/-18 site exhibiting the highest binding affinity. Transfection of site-directed mutated constructs in HepG2 cells indicated that the RORalpha1 effect is predominantly mediated by the -23/-18 site. This site is conserved in the mouse apo C-III gene promoter. Moreover, RORalpha binds to the equivalent mouse site and activates constructs containing three copies of the mouse site cloned in front of an heterologous promoter. Taken together, our data identify RORalpha as a transcriptional regulator of apo C-III gene expression, providing a novel, physiological role for RORalpha1 in the regulation of genes controlling triglyceride metabolism.
Hexagonal Mesostructure in Powders Produced by Evaporation-Induced Self-Assembly of Aerosols from Aqueous Tetraethoxysilane Solutions (2002)

Spherical submicron mesoporous particles possessing two-dimensional hexagonal order have been produced by evaporation-induced self-assembly in aerosols generated from acidic (pH ≈ 2) aqueous solutions of tetraethoxysilane (TEOS) and the surfactant cetyltrimethylammonium bromide (CTAB). Particle internal structure consists of multiple regions of hexagonally ordered tubular pore bundles with various orientations. Exploration of a broad range of CTAB and TEOS content showed that hexagonally ordered particles with Brunauer−Emmett−Teller surface areas of 700−1300 m2/g are produced when the CTAB/Si ratio is in the range 0.09 < CTAB/Si < 0.28. The mean pore diameter in ordered material is nearly constant at 2.8−3.0 nm, while wall thickness decreases from approximately 1 to 0.6 nm as the CTAB/Si ratio increases over that range. Hexagonal order is lost very abruptly for CTAB/Si < 0.09, with a corresponding rapid loss of surface area. Similar results were found for a solution pH of 1−3; however, a solution pH above 3.5 led to particles that appeared to be agglomerates of precipitated nanoparticles. Aerosol reactor temperatures from 30 to 550 °C were explored, with ordered particles produced under appropriate conditions at all temperatures. Lower reactor temperatures produced more highly ordered particles; however, reactor temperatures below approximately 125 °C can lead to particle coalescence on the collection filter. Coalescence occurs when silica condensation reactions are not sufficiently promoted to fix the individual particle structure before collection.
Effect of Long-Chain ω-3 Fatty Acids and Lutein + Zeaxanthin Supplements on Cardiovascular Outcomes (2014)

clinicaltrials.gov Identifier: NCT00345176.
Catalytic Debenzylation. III. The Influence of α-Substitution on the Ease of Hydrogenolysis<sup>1</sup> (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic Debenzylation. III. The Influence of α-Substitution on the Ease of Hydrogenolysis1Richard Baltzly and Peter B. RussellCite this: J. Am. Chem. Soc. 1953, 75, 22, 5598–5602Publication Date (Print):November 1, 1953Publication History Published online1 May 2002Published inissue 1 November 1953https://pubs.acs.org/doi/10.1021/ja01118a036https://doi.org/10.1021/ja01118a036research-articleACS PublicationsRequest reuse permissionsArticle Views357Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Challenging perspectives on learning and teaching in the disciplines: the academic voice (2012)

AbstractThis article reports on a study of academic staff perspectives on disciplinary communities and skill development in disciplinary contexts. Fifty-five academic staff were interviewed across eight disciplines in four Australian universities. Responses of historians and mathematicians are the focus of this article. A socio-constructivist framework informed analysis of academics' views about disciplinary cultures and skill development in disciplinary settings. Findings highlight discipline-based patterns in staff views about the value of generic skills in the curriculum. However, there was no apparent disciplinary effect in academics' views about belonging to a teaching community. Rather, sociocultural forces, particularly at the department level, appear to play the strongest role in this regard. The article argues for the influence of sociocultural factors on academics' perceptions of disciplinary tribes and territories in a changing policy environment. It has implications for institutional leaders and academic practitioners, highlighting challenges for supporting academic staff in disciplinary teaching communities.Keywords: disciplinesidentityacademic practiceacademic experiencesgeneric skills AcknowledgementsThis study was funded by the Australian Research Council Discovery Project Scheme. Project chief investigators were Professor Richard James (CSHE, University of Melbourne) and Professor Kerri-Lee Krause (University of Western Sydney). Several colleagues have contributed to this project. Key contributors were: Associate Professor Gay Baldwin, Robyn Garnett, Dr Anna Jones (formerly from the University of Melbourne); and Associate Professor Sharon Parry (University of Southern Cross). We gratefully acknowledge the student and academic staff interviewees who have made this project possible.
Immunogenetics Sequence Annotation: the Strategy of IMGT based on IMGT-ONTOLOGY. (2005)

IMGT, the international ImMunoGeneTics information system((R))(http://imgt.cines.fr) created in 1989, by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM), Université Montpellier II and CNRS, Montpellier, France, is a high quality integrated information system, secialized in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex of human and other vertebrates and related proteins of the immune system that belong to the IgSF and Mhc superfamilies. IMGT/LIGM-DB, the first and the largest IMGT database, manages more than 92,000 IG and TR nucleotide sequences from human and 150 other vertebrate species in May 2005. IMGT/LIGM-DB provides expertly annotated sequences and standardized knowledge based on IMGT-ONTOLOGY, the first ontology for immunogenetics and immunoinformatics. The strategy developed by IMGT, for the IG and TR nucleotide sequence annotation, involves two different approaches that depend on the nature of the sequences, genomic DNA (gDNA) or complementary DNA (cDNA).
Shape control in engineering of polymeric nanoparticles for therapeutic delivery (2015)

Nanoparticle-mediated delivery of therapeutics holds great potential for the diagnosis and treatment of a wide range of diseases. Significant advances have been made in the design of new polymeric nanoparticle carriers through modulation of their physical and chemical structures and biophysical properties. Nanoparticle shape has been increasingly proposed as an important attribute dictating their transport properties in biological milieu. In this review, we highlight three major methods for preparing polymeric nanoparticles that allow for exquisite control of particle shape. Special attention is given to various approaches to controlling nanoparticle shape by tuning copolymer structural parameters and assembly conditions. This review also provides comparisons of these methods in terms of their unique capabilities, materials choices, and specific delivery cargos, and summarizes the biological effects of nanoparticle shape on transport properties at the tissue and cellular levels.