gebhart/patrepeval huggingface dataset:
Applications of Aptasensors in Clinical Diagnostics (2012)

Aptamers are artificial oligonucleotides (DNA or RNA) selected in vitro that bind a broad range of targets with high affinity and specificity; a sensitive yet simple method to utilize aptamers as recognition elements for the development of biosensors (aptasensors) is to transduce the signal electrochemically. So far, aptasensors have been applied to clinical diagnostics and several technologies are in development. Aptasensors will extend the limits of current clinical diagnostics. Although the potential diagnostic applications are unlimited, the most current applications are foreseen in the areas of biomarker detection, cancer clinical testing, detection of infectious microorganisms and viruses. This review attempts to list examples of the research progresses of aptamers in biosensor platforms that have been published in recent years; in particular, we display cases of aptasensors that are already incorporated in clinical diagnostics or have potential applications in clinical diagnostics.
I.—On Sensations and Images (1910)

I.—On Sensations and Images Get access S. Alexander S. Alexander Search for other works by this author on: Oxford Academic Google Scholar Proceedings of the Aristotelian Society, Volume 10, Issue 1, 1 June 1910, Pages 1–35, https://doi.org/10.1093/aristotelian/10.1.1 Published: 25 July 2015
Collagenolytic Activity of Gingivae From Alloxan-Diabetic Rats (1973)

Gingivae from both control and alloxan-diabetic rats exhibited collagenolytic activity in tissue culture. The alloxan treatment, however, increased the collagenase activity of the cultured tissues. This effect may account for the increased urinary excretion of hydroxyproline, the altered collagen metabolism of gingivae, and the development of osteoporosis of the mandible in alloxan-diabetic rats demonstrated in our laboratory previously.3,4
The constituents of Schizandra chinensis Baill. I. The structures of gomisin A,B and C. (1975)

Three new schizandrin type lignans, gomisin A, B and C, were isolated from the fruits of Schizandra chinensis BAILL. (Schizandraceae) and their structures were elucidated to be I, II and III, respectively.
Die Unteilbarkeit der Weisheit. überlegungen zur sogenannten Paradieserzählung Gen 2f. und ihrer theologischen Tendenz (2002)

Article Die Unteilbarkeit der Weisheit. überlegungen zur sogenannten Paradieserzählung Gen 2f. und ihrer theologischen Tendenz was published on April 19, 2002 in the journal Zeitschrift für die alttestamentliche Wissenschaft (volume 114, issue 1).
Two channel TI-ADC for communication signals (2011)

Time-interleaved analog-to-digital converters (TI-ADCs) offer a significant increase in the available sample rate of ADCs. Their performance is degraded by timing and gain mismatches. Most of the literature on mismatch estimation and correction in TI-ADCs is concentrated on low-pass converting baseband signals. This paper provides a semi-blind solution, for both timing and gain mismatches correction, in the digital data section of a two-channel TI-ADC for band-pass input signals. This is a realistic communications system scenario. Modern system designs lean towards having the ADC interface with intermediate frequency (IF) signal in the analog section of a digital receiver rather than the DC centered, analog down converted, in-phase and quadrature pair.
MHC Class II Tetramers (2012)

MHC class II tetramers have emerged as an important tool for characterization of the specificity and phenotype of CD4 T cell immune responses, useful in a large variety of disease and vaccine studies. Issues of specific T cell frequency, biodistribution, and avidity, coupled with the large genetic diversity of potential class II restriction elements, require targeted experimental design. Translational opportunities for immune disease monitoring are driving the rapid development of HLA class II tetramer use in clinical applications, together with innovations in tetramer production and epitope discovery.
A glance at the law of champerty : the law (2016)

Achampertous agreement is one in terms of which a person provides a litigant with funds to prosecute an action in return for a share of the proceeds. It goes back to the Roman and Roman-Dutch periods. Originally known as pacta de quota litis, these agreements were looked upon with disfavour by the courts. They were considered to encourage speculative litigation and consequently abused the legal process.
Graft‐copolymerization of glycidyl methacrylate onto cotton cellulose (1994)

Abstract Glycidyl methacrylate was graft‐copolymerized onto cotton cellolose using both photo‐and chemical‐initiation techniques using different initiators. The photoinitiators used were uranyl nitrate, ceric ammonium nitrate, and benzoin ethyl ether, whereas the chemical initiators used were ceric ammonium nitrate and potassium persulfate. Optimization of various parameters of grafting, viz., time, temperature, initiator, and monomer concentrations, was carried out. Ceric ammonium nitrate gave the maximum and almost identical values of graft add‐on, by both grafting techniques, at equivalent cocentration of the monomer. Use of optimized conditions of ceric ammonium nitrate‐photoinitiated grafting for sodium hydroxide‐swollen substrate as well as for grafting baths incorporating acids enhanced the graft level. © 1994 John Wiley & Sons, Inc.
Detection of Vibrationally Excited Homonuclear Diatomic Molecules by Raman Spectroscopy (1971)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation L. Y. Nelson, A. W. Saunders, A. B. Harvey, G. O. Neely; Detection of Vibrationally Excited Homonuclear Diatomic Molecules by Raman Spectroscopy. J. Chem. Phys. 15 November 1971; 55 (10): 5127–5128. https://doi.org/10.1063/1.1675633 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioThe Journal of Chemical Physics Search Advanced Search |Citation Search
Der Wahrscheinlichkeitsbegriff (1986)

ZusammenfassungBevor wir den Begriff „Wahrscheinlichkeit“ einführen, beschäftigen wir uns mit den Grundbausteinen der Wahrscheinlichkeitsrechnung, den sogenannten zufälligen Ereignissen.
Decyanation of vitamin B <sub>12</sub> by a trafficking chaperone (2008)

The mystery of how the cyanide group in vitamin B(12) or cyanocobalamin, discovered 60 years ago, is removed, has been solved by the demonstration that the trafficking chaperone, MMACHC, catalyzes a reductive decyanation reaction. Electrons transferred from NADPH via cytosolic flavoprotein oxidoreductases are used to cleave the cobalt-carbon bond with reductive elimination of the cyanide ligand. The product, cob(II)alamin, is a known substrate for assimilation into the active cofactor forms, methylcobalamin and 5'-deoxyadenosylcobalamin, and is bound in the "base-off" state that is needed by the two B(12)-dependent target enzymes, methionine synthase and methylmalonyl-CoA mutase. Defects in MMACHC represent the most common cause of inborn errors of B(12) metabolism, and our results explain the observation that fibroblasts from these patients are poorly responsive to vitamin B(12) but show some metabolic correction with aquocobalamin, a cofactor form lacking the cyanide ligand, which is mirrored by patients showing poorer clinical responsiveness to cyano- versus aquocobalamin.
Treating viral venereal infections with the CO2 laser. (1982)

Viral venereal infections caused by herpes simplex virus 2 and papillomavirus (wart) are epidemic diseases in the United States. Unfortunately, these two infections have eluded conventional therapy to date. Therefore, 306 women were treated for viral venereal diseases with the CO2 laser. Two hundred twenty-eight patients were treated for condyloma acuminatum and 78 for genital herpes. All the patients who underwent treatment for herpes were enrolled in an investigative protocol. Since the viral organisms of both diseases replicate in either the basal or prickle cell layers of the epithelium, deep laser treatment is not necessary; treatment to a depth of 1 to 2 mm is adequate. The average power densities ranged from 311 to 660 w/cm2. Herpes patients responded with relief of pain and elimination of viral infectivity for that cycle. Patients with primary herpes were "cured" in 83% of cases. C. acuminatum could be eliminated with the CO2 laser in virtually every woman.
Neural ensemble decoding for topological quantum error-correcting codes (2020)

Topological quantum error-correcting codes are a promising candidate for building fault-tolerant quantum computers. Decoding topological codes optimally, however, is known to be a computationally hard problem. Various decoders have been proposed that achieve approximately optimal error thresholds. Due to practical constraints, it is not known if there exists an obvious choice for a decoder. In this paper, we introduce a framework which can combine arbitrary decoders for any given code to significantly reduce the logical error rates. We rely on the crucial observation that two different decoding techniques, while possibly having similar logical error rates, can perform differently on the same error syndrome. We classify each error syndrome to the decoder which is more likely to decode it correctly using machine learning techniques. We apply our framework to an ensemble of minimum-weight perfect matching (MWPM) and hard-decision re-normalization-group decoders for the surface code in the depolarizing noise model. Our simulations show an improvement of 38.4%, 14.6%, and 7.1% over the pseudothreshold of MWPM in the instance of distance 5, 7, and 9 codes, respectively. Lastly, we discuss the advantages and limitations of our framework and applicability to other error-correcting codes. Our framework can provide a significant boost to error correction by combining the strengths of various decoders. In particular, it may allow for combining very fast decoders with moderate error-correcting capability to create a very fast ensemble decoder with high error-correcting capability.
A boundary representation for form features and non-manifold solid objects (1991)

A boundary scheme derived from the concept of cell decomposition is presented for modelling form features. "Wedges" and "bundles" are added to the data structure for handling non-manifold edges and vertices in the same way as handling multiply connected faces with loops. With a feature-based and ajoint-based llttler-Poincar6 formulae, feature operators and joint operators are determined for manipulating the data structure which can explicitly represent both features and the joints between them and, at the same time, keep the topological adjacency relationships of the complete solid boundary. The properties of Euler operators are also discussed.
Photoconductor gain mechanisms in GaN ultraviolet detectors (1997)

GaN photoconductive detectors have been fabricated on sapphire substrates by metal organic vapor phase epitaxy and gas-source molecular beam epitaxy on Si (111) substrates. The photodetectors showed high photoconductor gains, a very nonlinear response with illuminating power, and an intrinsic nonexponential photoconductance recovery process. A novel photoconductor gain mechanism is proposed to explain such results, based on a modulation of the conductive volume of the layer.
SULFUR FROM SOUR GASES (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSULFUR FROM SOUR GASESFrederick G. Sawyer, Rodney N. Hader, L. Kermit Herndon, and Eugene MorningstarCite this: Ind. Eng. Chem. 1950, 42, 10, 1938–1950Publication Date (Print):October 1, 1950Publication History Published online1 May 2002Published inissue 1 October 1950https://pubs.acs.org/doi/10.1021/ie50490a003https://doi.org/10.1021/ie50490a003research-articleACS PublicationsRequest reuse permissionsArticle Views97Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
ISOLATION OF STIGMASTEROL AND βSITOSTEROL FROM PETROLEUM ETHER EXTRACT OF AERIAL PARTS OF AGERATUM CONYZOIDES (ASTERACEAE) (2011)

General phytochemical screening of the aerial parts of Ageratum conyzoides (Asteraceae) revealed the presence of steroids, terpenes, phenolic compounds, saponins, fatty acids, alkaloids. The aim of this study is to identify and characterize the bioactive principle from the aerial parts of the plant. It has wide folk medicinal use. For isolation of the compound, the dried aerial parts powder of Ageratum conyzoides was subjected to hot extraction with petroleum ether; this extract was saponified with alcoholic KOH and subjected to chromatography. Isolated compound were purified by chloroform. The isolation and purification afforded white crystalline powder which was subjected to physical, chemical and spectral identification by IR, 1H‐NMR, 13C‐NMR and GC‐MS. The compound was concluded as stigmasterol and β‐sitosterol.
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. (1984)

The Ca2+- and phospholipid-dependent protein kinase (C-kinase) binds tightly in the presence of Ca2+ to purified membranes of A431 human epidermoid carcinoma cells. The major membrane substrate for C-kinase is the epidermal growth factor (EGF) receptor. Phosphorylation of the EGF receptor is Ca2+-dependent and occurs at threonine and serine residues. After tryptic digestion of the receptor, three major phosphothreonine-containing peptides were identified. These are identical with three new phosphopeptides present in the EGF receptor isolated from A431 cells treated with either of the tumor promoters 12-O-tetradecanoylphorbol 13-acetate or teleocidin. C-kinase catalyzes phosphorylation at these same sites in purified EGF receptor protein. These results indicate that, in A431 cells exposed to tumor promoters, C-kinase catalyzes phosphorylation of a significant population of EGF receptor molecules. This phosphorylation of EGF receptors results in decreased self-phosphorylation of the EGF receptor at tyrosine residues both in vivo and in vitro and in decreased EGF-stimulated tyrosine kinase activity in vivo.
Temporomandibular joint nociception: effects of capsaicin on substance P-like immunoreactivity in the rabbit brain stem. (2002)

The present study revealed central nervous system changes following TMJ capsaicin treatment in rabbits.
Lights! Camera! Action! Zebrafish Embryos Caught on Film (2008)

For understanding what really goes on as an embryo develops, it is hard to beat a good movie, and this week German researchers released a set of potential blockbusters. The unusual movies, described this week online in Science (www.sciencemag.org/cgi/content/abstract/1162493) and available on the Web, show all the movements and divisions of cells in a zebrafish embryo during its first day of development. By the end of the movies, the fish have a recognizable backbone and heart as well as the early stages of several other organ systems.
Application of Wireless Sensor Networks for Indoor Temperature Regulation (2014)

Wireless sensor networks take a major part in our everyday lives by enhancing systems for home automation, healthcare, temperature control, energy consumption monitoring, and so forth. In this paper we focus on a system used for temperature regulation for residential, educational, industrial, and commercial premises, and so forth. We propose a framework for indoor temperature regulation and optimization using wireless sensor networks based on ZigBee platform. This paper considers architectural design of the system, as well as implementation guidelines. The proposed system favors methods that provide energy savings by reducing the amount of data transmissions through the network. Furthermore, the framework explores techniques for localization, such that the location of the nodes can be used by algorithms that regulate temperature settings.
Online monitoring of microcarrier based fibroblast cultivations with in situ microscopy (2007)

Animal cell culture is widely used in biotechnology for the production of many biological products. In situ microscopes acquire images directly from cell suspensions and analyze the images in matters of cell concentration, cell size distribution and cell morphology. Their applicability was already proven for yeast and suspended mammalian cell cultivations. In this work the in situ microscope was utilized to measure the level of colonization of fibroblasts on microcarrier surfaces during cultivation. For this study the murine cell line NIH-3T3 was used in combination with Cytodex 1 microcarriers. Cultivations were carried out in a 5 L stirred tank bioreactor equipped with the in situ microscope. Images were obtained sequentially with the in situ microscope over the whole cultivation time (900 images per sequence, 7.5 h per sequence on average). For the microcarrier analysis an image analysis algorithm based on a neural network was developed and implemented in the microscope analysis software.
Transcriptional Activation of the Heme Oxygenase Gene by Heme and Cadmium in Mouse Hepatoma Cells (1989)

Treatment of mouse hepatoma (Hepa) cells with heme or cadmium chloride in serum-free medium causes a rapid increase in the steady-state level of heme oxygenase (HO) messenger RNA. This increase is both dose- and time-dependent. Maximum accumulation of HO mRNA is observed 3 h after addition of either agent. Treatment of Hepa cells with heme or CdCl2 also stimulates the transcription of the HO gene, as judged by in vitro nuclear transcription run-on assays. The maximum rate of HO gene transcription occurs 2 h after treatment with either agent. Comparison of the relative increase in the rate of HO gene transcription with the relative increase in the level of HO mRNA demonstrates that transcriptional activation is the primary mechanism by which heme and cadmium produce the accumulation of HO mRNA in Hepa cells. Cadmium may also influence other processes involved in the expression of HO, since the time course of mRNA accumulation diverges from that of gene transcription. However, neither heme nor cadmium alters the rate of HO mRNA degradation. Cobalt chloride and heat shock, which are potent inducers of HO mRNA in rat liver and rat C6 glioma cells, respectively, have only a small effect on the level of HO mRNA in mouse hepatoma cells.
지역사회복지관 사례관리가 클라이언트의 삶의 만족 및 욕구변화에 미치는 영향에 관한 연구 - 서울시 N구 M 종합사회복지관 사례관리사업을 중심으로 - (2020)

최근 빈곤, 고령, 가족해체, 학대 등 복합적인 욕구를 가진 클라이언트 증가로 사례관리실천에 대한 관심이 증대되었으나, 클라이언트의 삶의 만족에 미치는 영향에 관한 연구는 미흡한 실정이다. 본 연구는 지역사회복지관 사례관리 만족도가 클라이언트의 삶의 만족 및 욕구변화에 미치는 영향을 검증하는데 목적이 있다. 이를 위해 N구 M 종합사회복지관 2019년 사례관리사업에 참여한 49명을 대상으로 SPSS 23.0와 PROCESS Macro를 활용한 분석을 하였으며, M 종합사회복지관 사례관리 대상자를 중심으로 사례관리 욕구 사전-사후검사를 실시하였다. 연구결과 첫째, 지역사회복지관 사례관리 만족도가 클라이언트 삶의 만족에 대하여 정(+)적인 영향으로 사례관리가 클라이언트의 삶의 질에 영향을 주는 긍정적인 요인으로 나타났다. 둘째, 지역사회복지관 사례관리 만족도가 클라이언트 삶의 만족에 영향을 미칠 때 사례관리 당사자 참여가 자립도모와 긍정적인 삶의 질 향상에 정(+)적인 조절작용을 하였다. 셋째, 지역사회복지관 사례관리가 클라이언트의 욕구변화에 효과성이 있음을 알 수 있었다. 분석에 따른 제언으로 첫째, 사례관리자의 역량강화를 위한 슈퍼비전 및 교육이 필요하다. 둘째, 사례당사자의 주도적 참여를 위한 실천이 중요하다. 셋째, 강점관점에 따른 사례개입이 요구된다. 이처럼 본 연구는 당사자주의에 입각한 사례관리를 통해 사례관리의 성과 및 만족도가 당사자욕구변화와 삶의 질에 유의미한 영향력이 있다는 검증을 통해 사례관리 실천방향에 관한 함의를 제시하였다는데 의의가 있다.
An Architectural Overview of QNX (1992)

This paper presents an architectural overview of the QNX operating system. QNX is an OS that provides applications with a fully network- and multi-processor-distributed, realtime environment that delivers nearly the full, device-level performance of the underlying hardware. The OS architecture used to deliver this operating environment is that of a realtime microkernel surrounded by a collection of optional processes that provide POSIX- and UNIX-compatible system services. By including or excluding various resource managers at run time, QNX can be scaled down for ROM-based embedded systems, or scaled up to encompass hundreds of processorsÅ either tightly or loosely connected by various LAN technologies. Confor-mance to POSIX standard 1003.1, draft standard 1003.2 (shell and utilities) and draft standard 1003.4 (realtime) is maintained transparently throughout the distributed environment.
Anisotropic Heatsinks for Heat-Assisted Magnetic Recording (2020)

The relevance of anisotropic heatsinks for heat-assisted magnetic recording (HAMR) is investigated. First, 3-D thermal modeling is used to demonstrate that the heatsink performance on a glass substrate is determined by the heatsink in-plane thermal conductivity. The out-of-plane thermal conductivity has almost no impact on the heatsink ability to carry heat away from the hot spot. As a result, an anisotropic heatsink can be a good alternative to some conventional isotropic heatsink materials when its in-plane thermal conductivity is larger than that of the isotropic material. Second, time-domain thermo-reflectance (TDTR) measurements are presented to extract both the in-plane and the out-of-plane thermal conductivities of a (Cu/Ta) multilayer heatsink. The sensitivity to in-plane thermal conductivity is achieved by using small laser beam sizes and by combining measurements at multiple modulation frequencies on both a low and a high thermally conductive substrate. The fitting of all TDTR spectra gives for the (Cu[5.1]/Ta[1.4]) multilayers an effective out-of-plane thermal conductivity of 11.5 W/mK and an in-plane thermal conductivity of 69 W/mK. These thermal properties make such multilayer material an interesting candidate as HAMR heatsink, equivalent to a 70 W/mK isotropic material.