gebhart/patrepeval huggingface dataset:
Un enterramiento múltiple del yacimiento calcolítico de Humanejos (Parla, Madrid) desde una perspectiva tafonómica: Agrupando y reagrupando la familia (2014)

El artículo da a conocer una fosa de enterramiento múltiple localizada en Humanejos (Parla, Madrid), un gran pobladode “silos” Calcolítico. Una primera parte se dedica al estudio antropológico y paleopatológico de ocho individuosinhumados en dos niveles. Los seis del nivel inferior pertenecen posiblemente a un mismo grupo familiar. En unasegunda parte, a través del estudio tafonómico, se reconstruye la secuencia de inhumación que, a juzgar por el desplazamientoparcial de uno de los cuerpos, se realizó, al menos, en tres momentos diferentes. Los gestos de colocacióny traslado estuvieron orientados a reproducir una escenografía dedicada a destacar los roles desempeñadospor algunos de los miembros del grupo.Palabras clave: Calcolítico, colectivismo funerario, Tafonomía, MadridAbstractThis contribution presents a multiple burial in pit from Humanejos site, a large Chalcolithic settlement located in Parla, Madrid. The first part deals with the anthropological and palaeopathological study of eight indivials buried in two stratigraphic levels. The six individuals from the lower level may belong to the same family. In a second part the taphonomic study reconstruct the sequence burial. This analysis shows that -given to the partial displacement of one of the bodies-, the burial took place at least three different times. Placement gestures and movements could be aimed to reproduce a scene dedicated to highlight the roles played by some of the group members.Keywords: Chalcolithic, collective burial, Taphonomy, Madrid.
Ginsenoside Rg1 inhibits the TSLP production in allergic rhinitis mice (2013)

Recent study reports that Korean red ginseng reduces the nasal allergic inflammatory reaction in an allergic murine model. However, the contribution of ginsenoside Rg1 (RG1) and its mechanisms on allergic rhinitis (AR) have not been elucidated. In this study, we evaluated the important activities of RG1 in the ovalbumin (OVA)-induced AR mice. RG1 significantly reduced the levels of thymic stromal lymphopoietin (TSLP) and interleukin (IL)-1β compared with the AR control mice. Allergic symptom such as rub scores and biomarkers such as spleen weight, histamine, IgE and IgG(1) in the RG1 group were decreased compared with the AR mice. The levels of interferon-γ were enhanced while the levels of IL-4 were reduced in the RG1 group. In the RG1 group, the eosinophils and mast cells infiltration increased by OVA were also decreased. RG1 reduced the levels of inflammation-related protein. RG1 inhibited the caspase-1 activity in nasal mucosa tissue. In addition, RG1 inhibited the production of TSLP and IL-1β and the activations of caspase-1, receptor interacting protein 2, IκB kinase-β and nuclear factor-κB/Rel A in activated HMC-1 cells. Our results indicate that RG1 has the inhibitory effect of TSLP production and caspase-1 activity in AR experimental model.
Application of (methyl-11C)-methionine in the multicellular spheroid system. (1991)

Human glioma (U-343 MGa) and human colon carcinoma (HT-29) cell lines were cultured as multicellular spheroids, and the accumulations of the L- and D-enantiomers of 11C-methionine were investigated. The accumulation of radioactivity in the spheroids was expressed as relative counts, by dividing the radioactivity measured in the spheroid with the radioactivity of the same volume of the incubation medium. The experiments were verified using 14C-labeled L- and D-methionine. The influence of spheroid volume, specific activity, incubation time, washing time, and the environmental temperatures were investigated. The spheroid model was used to determine the effect of the lipoxygenase inhibitors BW A4C and AA-861, the ether-phospholipid type PAF-antagonist CV-6209 and the protein synthesis inhibitor cycloheximide on methionine uptake. The results showed that 11C-L-methionine can be applied in the study of drug effects on multicellular tumor cell aggregates.
Relationship of the Pulmonary Artery End-Diastolic Pressure to the Left Ventricular End-Diastolic and Mean Filling Pressures in Patients With and Without Left Ventricular Dysfunction (1970)

The relationship of the left ventricular end-diastolic pressure (LVEDP) and the pulmonary arterial "wedge" mean pressure (PAWMP) to the pulmonary artery end-diastolic pressure (PAEDP) was investigated by cardiac catheterization in 71 subjects. Pressure records were obtained simultaneously or immediately consecutively. In 15 subjects with normal LV function (LVEDP, 4 to 12 mm Hg) PAEDP was within 3 mm Hg of LVEDP (r = 0.70, P < 0.01) and within 3 mm Hg of PAWMP (r = 0.69, P < 0.01) in every instance. In 56 patients with LV dysfunction (LVEDP, 12 to 55 mm Hg), PAEDP was lower than LVEDP in 42, equal to LVEDP in six, and higher than the LVEDP in eight, who were in atrial fibrillation or had increased pulmonary vascular resistance (PVR). PAEDP correlated closely with PAWMP (r = 0.92, P < 0.001). In 30 patients with LV dysfunction in sinus rhythm, an a wave was identified in the PA pressure tracing (PA a ) prior to systole which coincided in time and magnitude to the PAW a wave and was considered to represent retrograde transmission of the left atrial contraction wave. The PA a pressure was within 5 mm Hg of the LVEDP (r = 0.94, P < 0.001) in all except four patients, two of whom had elevated PVR. Thus, in the presence of LV dysfunction and elevated LVEDP, PAEDP correlated well with PAWMP, but failed to represent LVEDP accurately, while PA a wave pressure closely reflected LVEDP except when PVR was markedly increased.
ECDC publishes the annual epidemiological report 2012 (2013)

Preview this article: ECDC publishes the annual epidemiological report 2012, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/18/10/art20418-en-1.gif
Recent developments in nanowires for bio-applications from molecular to cellular levels (2016)

This review highlights the most promising applications of nanowires for bioanalytical chemistry and medical diagnostics. The materials discussed here are metal oxide and Si semiconductors, which are integrated with various microfluidic systems. Nanowire structures offer desirable advantages such as a very small diameter size with a high aspect ratio and a high surface-to-volume ratio without grain boundaries; consequently, nanowires are promising tools to study biological systems. This review starts with the integration of nanowire structures into microfluidic systems, followed by the discussion of the advantages of nanowire structures in the separation, manipulation and purification of biomolecules (DNA, RNA and proteins). Next, some representative nanowire devices are introduced for biosensors from molecular to cellular levels based on electrical and optical approaches. Finally, we conclude the review by highlighting some bio-applications for nanowires and presenting the next challenges that must be overcome to improve the capabilities of nanowire structures for biological and medical systems.
Plasma window characterization (2007)

Parameters of an arc Ar plasma discharge used as a plasma window with a discharge current of ∼50A and a voltage of ∼58V are presented. It is shown that this arc discharge allows one to decrease the pressure at the low pressure end of the plasma window almost 380 times using relatively low pumping at the low pressure end of the plasma window. Calculations of the plasma parameters and their spatial distribution using a simple wall-stabilized arc model showed a satisfactory agreement with the experimentally obtained data. It is shown that a significant decrease in gas flow through the plasma window occurs due to the increase in plasma viscosity. An improvement of the plasma window ignition and some of its design aspects are described as well.
Toward a modern theory of adaptive networks: Expectation and prediction. (1981)

Many adaptive neural network theories are based on neuronlike adaptive elements that can behave as single unit analogs of associative conditioning. In this article we develop a similar adaptive element, but one which is more closely in accord with the facts of animal learning theory than elements commonly studied in adaptive network research. We suggest that an essential feature of classical conditioning that has been largely overlooked by adaptive network theorists is its predictive nature. The adaptive element we present learns to increase its response rate in anticipation of increased stimulation, producing a conditioned response before the occurrence of the unconditioned stimulus. The element also is in strong agreement with the behavioral data regarding the effects of stimulus context, since it is a temporally refined extension of the Rescorla-Wagner model. We show by computer simulation that the element becomes sensitive to the most reliable, nonredundant, and earliest predictors of reinforcement . We also point out that the model solves many of the stability and saturation problems encountered in network simulations. Finally, we discuss our model in light of recent advances in the physiology and biochemistry of synaptic mechanisms.
Dynamics and Control of Satellite Relative Motion: Designs and Applications (2009)

This dissertation proposes analytic tools for dynamics and control problems in the perspective of large-scale relative motion without perturbations. Specifically, we develop an exact and efficient analytic solution of satellite relative motion using a direct geometrical approach in spherical coordinates. The resulting solution is then transformed into general parametric equations of cycloids and trochoids. With this transformation, the dissertation presents new findings for design rules and classifications of closed and periodic parametric relative orbits. A new observation from the findings states that the orbit shape resulting from the relative motion dynamics of circular orbit cases in polar views are exactly the same as the parametric curves of cycloids and trochoids. The dynamics problem of satellite relative motion is expanded to include the design of satellite constellations for multiple satellite systems. A Parametric Constellation (PC) is developed to create an identical constellation pattern, or repeating space track, of target satellites with respect to a base satellite. In this PC theory, the number of target satellites is distributed using a real number system for node spacing. While using a base satellite orbit as the rotating reference frame, the PC theory consists of satellite phasing rules and closed form formulae for designing repeating space tracks. The evaluation of the PC theory is illustrated through it’s comparison to the existing Flower Constellation theory in terms of node spacing distribution and constellation design process. For the control problems, the efficient analytic solution is applied to the reference trajectory of satellite relative tracking control systems for inter-satellite links. Two types of relative tracking control systems are developed and each is evaluated to determine which is more appropriate for practical applications of inter-satellite links. All of the proposed analytic solutions and tools in this dissertation will be useful for the mission analysis and design of relative motions involving a two or more satellite system.
Computing the nxm shortest path efficiently (2000)

Computation of all the shortest paths between multiple sources and multiple destinations on various networks is required in many problems, such as the traveling salesperson problem (TSP) and the vehicle routing problem (VRP). This paper proposes new algorithms that compute the set of shortest paths efficiently by using the A<sup>*</sup> algorithm. The efficiency and properties of these algorithms are examined by using the results of experiments on an actual road network.
Nanoconfinement effects in energy storage materials (2011)

Nanoconfinement effects have been studied to understand and to modify thermodynamic and kinetic properties of energy storage materials and to improve their cyclic behaviour. The paper addresses various aspects in the research and development of hydrogen storage materials and batteries. Fundamental relationships and the state-of-the art in the prediction of properties and experimental observations will be outlined and structure-property-relationships will be discussed for some hydrogen storage materials. Similar nanoconfinement effects in lithium battery anode materials will be addressed.
A comparison of night vision simulation methods for video (2014)

The properties of the human vision change depending on the absolute luminance of the perceived scene. The change is most noticeable at night, when cones lose their sensitivity and rods activate. This change is imitated in video footage using various tricks and filters. In this study, we compared 4 algorithms that can realistically simulate the appearance of night scenes on a standard display. We conducted a subjective evaluation study to compare the results of night vision simulation with a reference footage dimmed using a photographic filter to determine which algorithm offers the greatest accuracy. The results of our study can be used in computer graphics rendering to apply the most realistic simulation of night vision to the rendered night scenes or in photography to reproduce photographs taken at night as similar as possible to how the human eye would see them.
Use of [<sup>3</sup>H]Triphenylmethylphosphomum Cation for Estimating Membrane Potential in Neuroblastoma Cells (1984)

The lipophilic permeant cation [3H]triphenylmethylphosphonium (TPMP) was used to estimate membrane potential in neuroblastoma N1E 115 cells under carefully controlled conditions. The cation distributes into the cells only in the presence of a lipophilic anion, and tetraphenylboron and picrate have been used for this purpose. The potassium salt of tetraphenylboron is poorly soluble, so that studies in high [K+] media are difficult with this anion whereas picrate, at the concentrations required, hyperpolarises the cells. The effect of muscarinic receptor activation was investigated by treating cells with carbachol but no effect was seen either on [3H] TPMP distribution or electrophysiological parameters. The use of [3H]TPMP for qualitative and quantitative evaluation of membrane potential in these cells is discussed.
Benchmarking IP blacklists for financial botnet detection (2010)

Every day, hundreds or even thousands of computers are infected with financial malware (i.e. Zeus) that forces them to become zombies or drones, capable of joining massive financial botnets that can be hired by well-organized cyber-criminals in order to steal online banking customers' credentials. Despite the fact that detection and mitigation mechanisms for spam and DDoS-related botnets have been widely researched and developed, it is true that the passive nature (i.e. low network traffic, fewer connections) of financial botnets greatly hinder their countermeasures. Therefore, cyber-criminals are still obtaining high economical profits at relatively low risk with financial botnets. In this paper we propose the use of publicly available IP blacklists to detect both drones and Command & Control nodes that are part of financial botnets. To prove this hypothesis we have developed a formal framework capable of evaluating the quality of a blacklist by comparing it versus a baseline and taking into account different metrics. The contributed framework has been tested with approximately 500 million IP addresses, retrieved during a one-month period from seven different well-known blacklist providers. Our experimental results showed that these IP blacklists are able to detect both drones and C&C related with the Zeus botnet and most important, that it is possible to assign different quality scores to each blacklist based on our metrics. Finally, we introduce the basics of a high-performance IP reputation system that uses the previously obtained blacklists' quality scores, in order to reply almost in real-time whether a certain IP is a member of a financial botnet or not. Our belief is that such a system can be easily integrated into e-banking anti-fraud systems.
Direct detection of circulating microRNAs in serum of cancer patients by coupling protein-facilitated specific enrichment and rolling circle amplification (2014)

We have developed a simple method for direct detection of circulating microRNAs in serum by using the p19 protein-functionalized magnetic beads (PFMBs) for specific enrichment and rolling circle amplification (RCA). The detection limit for microRNAs is 1 fM. Therefore, the proposed method has the potential of being used in the analysis of circulating microRNAs and clinical diagnosis.
Life After 2000--The Debate Goes On (1984)

Journal Article Life After 2000—The Debate Goes On Get access Peter H. Raven, Peter H. Raven Missouri Botanical Garden Search for other works by this author on: Oxford Academic Google Scholar Julian L. Simon, Julian L. Simon University of Maryland Search for other works by this author on: Oxford Academic Google Scholar Barry Commoner, Barry Commoner Queens College, City University of New York Search for other works by this author on: Oxford Academic Google Scholar Danny J. Boggs, Danny J. Boggs US Department of Energy Search for other works by this author on: Oxford Academic Google Scholar Laura Tangley Laura Tangley Search for other works by this author on: Oxford Academic Google Scholar BioScience, Volume 34, Issue 8, September 1984, Pages 477–479, https://doi.org/10.1093/bioscience/34.8.477 Published: 01 September 1984
Asymmetric baseband equalization (1988)

For asymmetric channels, the performance of symmetric and asymmetric baseband equalizers is analyzed. For both structures, the frequency response and the output mean-square error (MSE) of the optimum equalizer of infinite length are given. Several specific modem imperfections are considered, and the associated CNR (carrier-to-noise ratio) degradation is computed for 256-QAM systems. The results show that while asymmetric equalizers lead to a very limited compensation of modem imperfections, asymmetric equalizers lead to a dramatic improvement and, in the range of practical interest, reduce the CNR degradation almost to zero.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Pathophysiology of endothelin and medical emergencies. (2003)

Pathophysiology of endothelin-1, a vasoconstrictor and a mitogenic peptide, has been extensively investigated in recent years. The authors have examined the main clinical and experimental evidence regarding the involvement of this peptide in some medical emergencies, namely myocardial infarction, stroke and hepato-renal syndrome. Literature data suggest an emerging pathophysiological role for endothelin in such clinical conditions.
Simulation of semiconductor opening switch physics (2002)

Summary form only given. Semiconductor opening switches (SOS) are able to interrupt currents at density levels of up to 10 kA/cm2 in less than 10 ns. If stacked, SOS diodes can hold off voltage levels above a few 100 kV. They are therefore ideal for the design of compact high voltage pulse generators of the GW-class for industrial applications. The aim of this work was to improve our understanding of the opening process in a semiconductor diode of SOS-type with a doping profile of p+pnn+ structure. To simulate the physical processes inside this diode the code POSEOSS was developed. It contains a detailed physical model of charge carrier transport under the influence of density gradients and electric fields and considers all relevant generation and recombination processes. It possess a large degree of flexibility and allows to carry out parameter studies to determine the influence of different physical quantities, like doping and impurity levels. Applying the code, using realistic values for the charge carrier mobility, it was found that the opening process starts first at the n-n+ boundary, in contradiction to results published by other authors. Based on the simulation results a simplified SOS equivalent circuit model has been developed which can be used in the circuit simulation program PSpice. A new pulse generator scheme based on inductive stores is proposed, in which power multiplication is achieved by unloading the inductors, previously charged in series, in parallel. This scheme can be considered as the inductive equivalent of a Marx generator. We present Pspice simulations of such a scheme based on semiconductor opening switches. The theoretical results were compared to measurements obtained with a simple experimental set-up using two 100 kV SOS-switches. The measurements showed good agreement with the simulation results. Further improvements seem possible by adapting the SOS device structure to the specific generator circuit.
Apoptotic cells: a source of autoantigens for antiphospholipid antibodies. (128.32) (2007)

Abstract Antiphospholipid antibodies (APAs) are detected in various autoimmune diseases, such as antiphospholipid syndrome (APS) and systemic lupus erythematosus. In addition to their binding to negatively charged phospholipids, APAs often cross-react with other molecules. Their biological effects are not fully understood. Apoptotic cells are a potential source of auto-antigens during systemic autoimmunity. Inefficient clearance of apoptotic cells results in the development of autoimmune manifestations and intracellular antigens such as nucleosomes become accessible during apoptosis. We examined a panel of monoclonal APAs generated from NZW/BXSB F1, a strain which spontaneously develops autoimmune symptoms reminescent of APS. These APAs did not bind to live cells, but reacted strongly with different structures within apoptotic cells. Further analysis with various inhibitors indicated that the binding of APAs to apoptotic cells depends on specific caspase activities and on the modification of auto-antigens by reactive oxygen species (ROS). Therefore, apoptotic cells provide a potential source of APA antigens that may not be limited to phospholipids. Our data also indicate that physical accessibility and apoptosis-specific modification of auto-antigens by caspases or ROS are crucial factors for APA-antigen interactions. NIH, AHA, Lupus Research Institute
Simplified in situ syntheses of anhydrous pentacarbonylhydromanganese (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimplified in situ syntheses of anhydrous pentacarbonylhydromanganeseJ. A. Gladysz, Wilson Tam, G. M. Williams, Dennis Lee Johnson, and David W. ParkerCite this: Inorg. Chem. 1979, 18, 4, 1163–1165Publication Date (Print):April 1, 1979Publication History Published online1 May 2002Published inissue 1 April 1979https://pubs.acs.org/doi/10.1021/ic50194a053https://doi.org/10.1021/ic50194a053research-articleACS PublicationsRequest reuse permissionsArticle Views164Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts