gebhart/patrepeval huggingface dataset:
Variations in the cytoskeletal interaction and posttranslational modification of the CD44 homing receptor in macrophages. (1991)

Murine CD44 is a cell surface glycoprotein that is thought to play a role in leukocyte migration. We studied the structure and expression of CD44 on two populations of macrophages: those that reside in the peritoneum of unprimed mice, and those that have been elicited to migrate into the peritoneum by the intraperitoneal injection of agents that cause localized inflammatory responses. Our studies reveal structural variations in both the extracellular and intracellular domains of CD44 expressed by these two macrophage populations. The form of CD44 in elicited macrophages has an apparent molecular mass that is approximately 5 kD greater and more heterogenous than that in resident macrophages. This structural changes is posttranslational, extracellular, and apparently reflects increases in N-linked glycosylation. It is also specific for CD44 and does not occur with several other glycoproteins examined. This novel regulation of glycosylation may play an important role in the ability of CD44 to bind to different substrates, particularly lectin-like ligands. In addition, we demonstrate that CD44 in resident macrophages is divided into two pools, one containing nonphosphorylated, cytoskeletally associated CD44, and one containing phosphorylated, unassociated CD44. In contrast, CD44 on the surface of elicited macrophages does not associate with the cytoskeleton. The attachment of CD44 to the cytoskeleton involves either direct or indirect association with actin. The regulated association of CD44 with the cytoskeleton suggests that it may influence or be influenced by macrophage mobility.
Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets. (1979)

The presence of specific Factor VIII/von Willebrand factor (FVIII/vWF) binding sites on human platelets has been demonstrated by using 125I-FVIII/vWF and washed human platelets. Binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. Binding of 125I-FVIII/vWF to platelets can be competitively inhibited by unlabeled human or bovine FVIII/vWF, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of Ricinus communis. Scatchard analysis of binding data indicated that the dissociation constant of FVIII/vWF receptors is 0.45--0.5 nM. There are 31,000 binding sites per platelet at 1 mg/ml of ristocetin concentration. The optimal pH range for binding is from 7.0 to 7.5. At a concentration of 2 mM, EGTA inhibits 86% of the binding; however, 20 mM of Ca++, Mg++, or EDTA have little effect. Binding sites for FVIII/vWF were found only on platelets, and no significant binding was detected with human erythrocytes or polymorphonuclear leukocytes.
Thalamic neurodegeneration in multiple sclerosis (2002)

Multiple sclerosis is still regarded primarily as a disease of the white matter. However, recent evidence suggests that there may be significant involvement of gray matter. Here, we have used magnetic resonance imaging and magnetic resonance spectroscopy in vivo and histopathology postmortem to estimate thalamic neuronal loss in patients with multiple sclerosis. Our results show that neuronal loss in multiple sclerosis can be substantial (30-35% reduction). We conclude that a neurodegenerative pathology may make a major contribution to the genesis of symptoms in multiple sclerosis.
An Overview of Repository Technology (1994)

A repository is a shared database of information about engineered artifacts. We define a repository manager to be a database application that suPports checkout/checkin, version and configuration management, notification, context management, and workflow control. Since the main value of a repository is in the tools that use it, we discuss technical issues of integrating tools with repositories. We also discuss how to implement a repository manager by layering it on a DBMS, focusing especially on issues of programming interface, performance, distribu,; tion, and interoperability.
On the kinetics of Portland cement hydration in the presence of selected chemical admixtures (1993)

The complete phase compositIOn of cement pastes prepared from a laboratory-made Portland cement with no admixtures and with added CaCl 2 (1·0%), sucrose (0·2 %) and melamine sulphonate resin (1 ·0 %) has been determined between 6 min and 28 days of hydration. Each of the additives affected the hydration progress of the cement, however the hydration kinetics of the individual clinker minerals were altered in different ways.
Readiness for Learner Autonomy: What do our learners tell us? (2001)

In higher education teaching, enhancing learner autonomy has become a key concern for curriculum planners and classroom teachers. The significant body of research about learner autonomy in language learning over the last 20 years (e.g. Holec 1981, 1988; Riley 1985; Dickinson 1987, 1992; Wenden & Rubin 1987; Little, 1991; Dam, 1995; Benson & Voller, 1997) has indicated an on-going search for more understanding of how learner autonomy can be implemented in different contexts. \n</br>\nThis paper is based on a research study which was conducted in the Hong Kong Polytechnic University in Hong Kong. The study explores learners' attitudes and expectations of language learning, teacher and learner roles, their learning preferences and perceptions of learner autonomy. The paper reports the results and discusses their implication on the development of a learner-centred approach in higher education. </br>[Copyright of Teaching in Higher Education is the property of Routledge. Full article may be available at the publisher's website: </br>http://dx.doi.org/10.1080/13562510120078045]
Filtering Image Spam with Near-Duplicate Detection. (2007)

A new trend in email spam is the emergence of image spam. Although current anti-spam technologies are quite successful in filtering text-based spam emails, the new image spams are substantially more difficult to detect, as they employ a variety of image creation and randomization algorithms. Spam image creation algorithms are designed to defeat well-known vision algorithms such as optical character recognition (OCR) algorithms whereas randomization techniques ensure the uniqueness of each image. We observe that image spam is often sent in batches that consist of visually similar images that differ only due to the application of randomization algorithms. Based on this observation, we propose an image spam detection system that uses near-duplicate detection to detect spam images. We rely on traditional anti-spam methods to detect a subset of spam images and then use multiple image spam filters to detect all the spam images that “look ” like the spam caught by traditional methods. We have implemented a prototype system to achieve high detection rate while having a less than 0.001 % false positive rate. 1.
Entanglement between Rydberg excited state and ground-state spin wave (2016)

Here, we report on the successful storage of a true single photon using the Rydberg polariton and establishment of the entanglement between Rydberg excited state and the ground state spin wave experimentally, making a primary step towards the construction of a hybrid quantum interface.
Optimizing the Latent Space of Generative Networks (2017)

Generative Adversarial Networks (GANs) have achieved remarkable results in the task of generating realistic natural images. In most successful applications, GAN models share two common aspects: solving a challenging saddle point optimization problem, interpreted as an adversarial game between a generator and a discriminator functions; and parameterizing the generator and the discriminator as deep convolutional neural networks. The goal of this paper is to disentangle the contribution of these two factors to the success of GANs. In particular, we introduce Generative Latent Optimization (GLO), a framework to train deep convolutional generators using simple reconstruction losses. Throughout a variety of experiments, we show that GLO enjoys many of the desirable properties of GANs: synthesizing visually-appealing samples, interpolating meaningfully between samples, and performing linear arithmetic with noise vectors; all of this without the adversarial optimization scheme.
1.8 GHz tunable filter in Si technology (2002)

An active filter using integrated inductors has been implemented in Si bipolar technology. The filter has a second-order bandpass response, with quality factor tunable through Q enhancement and center frequency tunable through reactance multiplication. For a nominal center frequency of 1.8 GHz and a quality factor of 35, the filter has a 1 dB compression dynamic range of 40 dB, and draws 8 mA from a 3 V supply.
Adaptive Personalization of Web Search (2008)

An often stated problem in the state-of-the-art web search is its lack of user \nadaptation, as all users are presented with the same search results for a given \nquery string. A user submitting an ambiguous query such as ”java” with a strong \ninterest in traveling might appreciate finding pages related to the \nIndonesian island Java. However, if the same user searched for programming \ntutorials a few minutes ago, the situation would be completely different, and \ncall for programming-related results. Furthermore suppose our sample user \nsearches for ”java hashmap”. Again imposing her interest into traveling might \nthis time have the contrary effect and even harm the result quality. Thus the \neffectiveness of a personalization of web search shows high variance in \nperformance depending on the query, the user and the search context. To this \nend, carefully choosing the right personalization strategy in a \ncontextsensitive manner is critical for an improvement of search results.\n\nIn this thesis, we present a general framework that dynamically adapts the \nquery-result ranking to the different information needs in order to improve the \nsearch experience for the individual user. We distinguish three different \nsearch goals, namely whether the user re-searches known information, delves\ndeeper into a topic she is generally interested in, or satisfies an ad-hoc \ninformation need. We take an implicit relevance feedback approach that makes \nuse of the user’s web interactions, however, vary what constitutes the examples \nof relevant and irrelevant information according to the user’s search mode. We \nshow that incorporating user behavior data can significantly improve the \nordering of top results in a real web search setting.
A √N algorithm for mutual exclusion in decentralized systems (1985)

An algorithm is presented that uses only c√N messages to create mutual exclusion in a computer network, where N is the number of nodes and c a constant between 3 and 5. The algorithm is symmetric and allows fully parallel operation.
Dendritic cell-based vaccines in breast and gynaecologic cancer. (2003)

Major advances in understanding the functional interactions between tumour cells and the host immune system, in particular the generation and regulation of T cell immunity, have revived interest in cancer vaccination strategies. A crucial step for mounting an anti-tumour response is the capture, processing and presentation of tumour antigens (TA) to cognate T cells by professional antigen-presenting cells (APC), followed by their activation and clonal proliferation. Dendritic cells (DC) are potent APC with the unique ability to stimulate primary immune responses. Animal models have demonstrated that TA-charged DC can activate specific cytotoxic T cells (CTL) and even regression of established tumours in cancer-bearing hosts. These findings, as well as the elaboration of methods for generating large numbers of DC ex vivo, have provided a compelling rationale for using DC as potent adjuvants to deliver TA to the immune system in order to trigger or amplify an inadequate response. The capacity of TA-pulsed DC to induce significant CTL immunity translating into occasional therapeutic benefit has been documented in several clinical settings including B cell lymphoma, myeloma, melanoma, prostate, colon, ovarian and renal cell carcinoma. In this review, we summarize key biological functions of DC and focus on recent DC-based vaccination trials of breast, ovarian and cervical cancer.
Controlling Inkjet Fluid Kinematics to Achieve SOFC Cathode Micropatterns (2015)

Drop-on-demand inkjet printing - a mask-less, fine write, and high throughput technique - is attractive for fabricating miniature ceramic devices. In this study, high quality, fine-featured solid oxide fuel cell (SOFC) cathode micropatterns were demonstrated using inkjet printing. The influence of the droplet kinematic properties on final drop deposition was studied by adjusting ink temperature and droplet velocity to obtain a wide range of Weber and Z values, i.e. 0 < Weber < 57 and 0 < Z < 24. Terpineol-based inks were evaluated, with or without dispersant (polymeric ethyl cellulose) and/or active cathode material (La0.6Sr0.4Fe0.8Co0.2O3). The balance of inertia to the surface energy of the jetted droplet was found to play a prominent role in the stability of droplets. The Weber number was found to be the good predictor for stable jetting. At Weber > 35 printing defects from splashes and satellites were present. At Weber < 35 the droplets coalesced into uniform, round circles without splashes or satellite defects. Defect-free printing was essential toward achieving uniform micropatterens such as micro dot arrays or micro lines which are on the scale of 100 microns or less.
A computationally efficient EKF-vSLAM (2008)

This paper presents an efficient extended Kalman filter implementation of a single-camera visual simulataneous localization and mapping (vSLAM) algorithm, vSLAM is a novel algorithm for simultaneous localization and mapping problem widely studied in mobile robotics field. The algorithm is vision and odometry-based. The problem with the implementation of all SLAM algorithms is the state vector size and the full covariance matrix, which in large environments may become prohibitively large. In this paper we show that moving landmark from the state vector to the map vector, using the camera characteristics, can maintain a reasonable number of landmarks in the state vector and then reduce the computational complexity of the update loop. At each time the algorithm maintains the map vector, which contains invisible landmarks, separated from the state vector. We use a Pioneer II robot and motorized pan tilt camera models to implement the algorithm.
Altering Hydrogen Storage Properties by Hydride Destabilization through Alloy Formation:  LiH and MgH<sub>2</sub> Destabilized with Si (2004)

Alloying with Si is shown to destabilize the strongly bound hydrides LiH and MgH2. For the LiH/Si system, a Li2.35Si alloy forms upon dehydrogenation, causing the equilibrium hydrogen pressure at 490 °C to increase from approximately 5 × 10-5 to 1 bar. For the MgH2/Si system, Mg2Si forms upon dehydrogenation, causing the equilibrium pressure at 300 °C to increase from 1.8 to >7.5 bar. Thermodynamic calculations indicate equilibrium pressures of 1 bar at approximately 20 °C and 100 bar at approximately 150 °C. These conditions indicate that the MgH2/Si system, which has a hydrogen capacity of 5.0 wt %, could be practical for hydrogen storage at reduced temperatures. The LiH/Si system is reversible and can be cycled without degradation. Absorption/desorption isotherms, obtained at 400−500 °C, exhibited two distinct flat plateaus with little hysteresis. The plateaus correspond to formation and decomposition of various Li silicides. The MgH2/Si system was not readily reversible. Hydrogenation of Mg2Si appears to be kinetically limited because of the relatively low temperature, <150 °C, required for hydrogenation at 100 bar. These two alloy systems show how hydride destabilization through alloy formation upon dehydrogenation can be used to design and control equilibrium pressures of strongly bound hydrides.
MAMSK-OFDM Signal for RoF Access With Increased Tolerance Toward Frequency Offset (2013)

A novel multi-amplitude minimum shift keying (MAMSK) orthogonal frequency division multiplexing (OFDM) signal is proposed for 60-GHz radio-over-fiber (RoF) access system. It can increase the tolerance toward frequency offset of an OFDM signal due to the faster roll-off side-lobe. In the experiment, a 3.21-Gb/s 2AMSK-OFDM signal is transmitted over 22 km single mode fiber (SMF) and 5 m air link successfully. Compared with a conventional 8QAM-OFDM signal, the signal-to-interference ratio (SIR) of 2AMSK-OFDM is improved by 11.5 dB at a frequency offset of 0.15. The performance is improved by 1.7 dB under a normalized frequency offset (FO) of 0.2.
Electroactive bilayers employing conducting polymers. Part 2.—Speciation by in situ spectroscopy (1991)

Electrochemically driven charge trapping and untrapping reactions in polybithiophene/polyxylylviologen (PBT/PXV) bilayers have been studied using in situ transmission spectroscopy in the visible region. Charge transfer to the outer film is exclusively mediated by the conducting states of the inner film. The redox composition of the outer film was determined as a function of potential and injected charge in cyclic voltammetric experiments. During reduction of the outer film, the semi-reduced PXV+ species is the predominant product until essentially all the reactant PXV2+ is consumed. Production of fully reduced PXV0 depends on film thickness and voltage scan rate. Similarly, PXV+ is the predominant product of PBT+-mediated PXV0 oxidation, until PXV0 consumption is almost complete. Slow changes in the outer-film composition due to reaction with trace oxidant (presumed oxygen) in solution were detected.
A user level program transformation tool (1998)

Article Free Access Share on A user level program transformation tool Authors: François Bodin IRISA-INRIA, Campus de Beaulieu, 35042 Rennes, France IRISA-INRIA, Campus de Beaulieu, 35042 Rennes, FranceView Profile , Yann Mével IRISA-INRIA, Campus de Beaulieu, 35042 Rennes, France IRISA-INRIA, Campus de Beaulieu, 35042 Rennes, FranceView Profile , René Quiniou IRISA-INRIA, Campus de Beaulieu, 35042 Rennes, France IRISA-INRIA, Campus de Beaulieu, 35042 Rennes, FranceView Profile Authors Info & Claims ICS '98: Proceedings of the 12th international conference on SupercomputingJuly 1998Pages 180–187https://doi.org/10.1145/277830.277868Published:13 July 1998Publication History 16citation393DownloadsMetricsTotal Citations16Total Downloads393Last 12 Months24Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Diffusion of methyl bromide in soil (1989)

SUMMARY Phenomenological modelling is proposed for penetration by diffusion with aqueous dissolution of a gaseous constituent in non‐saturated soil when there is a thermodynamic imbalance between this gas phase constituent and the same constituent in solution. Non‐equilibrium experiments (Mignard & Benet, 1986) led to specifying the equation governing the kinetics of dissolution and measurement of the phenomenological coefficient for methyl bromide. The results of the model with dissolution imbalance are compared with those of models in the literature which assume immediate dissolution equilibrium in the treatment of soil with methyl bromide applied at the surface. The model developed gives profiles of concentration of substance in the soil in both liquid and gas phases, and makes it possible to judge the extent of the soil zone treated and to forecast what will be the behaviour of the substance.
The encyclopedia of microscopy and microtechnique (1973)

Comprehensive, alphabetically arranged articles about microscopic instruments, techniques, and applications. Intended for wide diversity of users, e. g., biologists, chemists, physicists, geologists, medical researchers, and industrial researchers. Long entries, signed by experts from numerous countries, also include references. Photographs, tables, diagrams, graphs, and drawings. Subject index.
<i>In situ</i> laser microprocessing of single self-assembled quantum dots and optical microcavities (2007)

The authors employ a focused laser beam both as a probe and as a local heat source to tune in situ, over a broad range and with resolution-limited accuracy, the quantized energy states of single optical microcavities and self-assembled quantum dots (QDs). The approach is demonstrated by bringing an optical mode of a microdisk into resonance with the emission of a single QD and by tuning spatially separated QDs in mutual resonance. This processing method may be used, e.g., to fabricate arrays of perfectly resonant QDs.
Heregulin Regulates the Ability of the ErbB3-binding Protein Ebp1 to Bind E2F Promoter Elements and Repress E2F-mediated Transcription (2004)

The ErbB3/4 ligand heregulin (HRG) profoundly affects cell growth and differentiation, but its mechanism of action is poorly understood. Ebp1, a protein isolated by its binding to ErbB3, inhibits cell growth and represses transcription of E2F-regulated cell cycle genes. Since Ebp1 shares 38% identity with a Schizosaccharomyces pombe DNA-binding protein, we postulated that Ebp1 could bind E2F consensus elements in an HRG-inducible manner, leading to transcriptional repression. We show here that GST-Ebp1 bound to the DNA sequence bound by the S. pombe protein. Whereas GST-Ebp1 alone failed to bind E2F1 promoter elements, Ebp1 contained in nuclear lysates associated with E2F1 consensus sequences in the E2F1 promoter. Endogenous Ebp1 was recruited to the E2F1 promoter in vivo as demonstrated by chromatin immunoprecipitation assays. Ebp1 bound E2F consensus oligonucleotides in association with E2F1, retinoblastoma protein, and HDAC2. HRG regulated the association of Ebp1 with E2F promoter sequences and enhanced the ability of Ebp1 to repress transcription. Our findings suggest that Ebp1, by linking HRG activation of membrane receptors to E2F gene activity, may be a downstream modulator of the effects of HRG on cell cycle progression.