gebhart/patrepeval huggingface dataset:
A novel wide-band differential amplifier (1992)

A novel configuration for an op.-amp.-based differential gainblock is presented. The analytical expressions are obtained, and the performance of the proposed circuit is examined in relation to the conventional circuit. Simulation and experimental results are presented which establish the superiority of the proposed differential amplifier over the conventional circuit. Numerical results are given. >
Liquid-phase catalytic oxidation of p-xylene (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLiquid-phase catalytic oxidation of p-xylenePavagada Raghavendrachar and Subramania RamachandranCite this: Ind. Eng. Chem. Res. 1992, 31, 2, 453–462Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February 1992https://pubs.acs.org/doi/10.1021/ie00002a001https://doi.org/10.1021/ie00002a001research-articleACS PublicationsRequest reuse permissionsArticle Views1993Altmetric-Citations134LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
CD1d-Restricted T Cells License B Cells to Generate Long-Lasting Cytotoxic Antitumor Immunity <i>In vivo</i> (2006)

Although resting B cells are known for being poorly immunogenic and for inducing T-cell tolerance, we have here attempted to test whether their immunogenicity could be enhanced by CD1d-restricted invariant T cells (iNKT) to a point where they could be used in cellular vaccines. We found that the addition of the iNKT ligand alpha-galactosylceramide (alphaGalCer) to peptide-loaded B cells overcame peptide-specific T-cell unresponsiveness and allowed for the generation of peptide-specific memory CTL immunity. This CTL was induced independently of CD4 T and natural killer cells but required iNKT and CD8 T cells. B cells directly primed CTL, and the alphaGalCer and the peptide must be presented on the same cell. Importantly, our B-cell-based vaccine is comparable in efficiency with dendritic cell-based vaccines, inducing similar CTL responses as well as providing an effective regimen for preventing and suppressing s.c. and metastatic tumors. Therefore, with the help of iNKT, peptide-pulsed B cells can establish long-lasting antitumor immunity and so show promise as the basis for an alternative cell-based vaccine.
Experience with a New Epimyocardial Pacing Lead in Children (1984)

A new permanent epimyocardial Medtronic 4951 "stab-in" or "fishhook" pacing electrode was implanted in 16 children. Identical technique, with particular attention to the direction of the coronary circulation, was utilized to implant the leads. There were 10 atrial implantations (5 active, 5 redundant) and 18 ventricular implantations (15 active, 3 redundant). Pacing modes were VVI (12), VDD (1), DVI (2), and DDD (1). Experience with the lead covers 280 patient months (3 days to 21.8 months, mean 14 months). Patients were followed monthly via telephonic transmission. With the exception of the single patient who expired three days after implantation, each patient has returned for follow-up analysis including chronic threshold determinations using the programming capabilities of the pulse generators. Only one lead required more than the minimum obtainable voltage output from the pulse generator to effect capture. No other lead required more than 5.0 volts at 0.5 ms pulse width. There have been no lead fractures or dislodgements. In this evaluation the Medtronic 4951 lead performed well in both atrium and ventricle in a group of children with diverse cardiac pathology. The small diameter of the lead and the low profile of the electrode are advantageous for use in pediatric patients.
The synthesis of cyclic and acyclic long‐chain arylpiperazine derivatives of salicylamide as serotonin receptor ligands (2008)

Abstract magnified image The 1‐arylpiperazine series of N ‐substituted 1,3‐benzoxazine‐2,4‐diones as well as O ‐ and N ‐substituted salicylamides with an n ‐propyl chain were synthesized in order to explore the effect of cyclic and acyclic salicylamide moieties on their binding affinity for 5‐HT 1A , 5‐HT 2A and 5‐HT 7 receptor sites. Target compounds 1 and 2 were prepared by a two‐step procedure, i.e. by alkylation of 1,3‐benzoxazine‐2,4‐dione or salicylamide with 1,3‐dibromopropane and next by condensation of 3‐bromopropyl intermediates with arylpiperazines; syntheses of 3‐bromopropyl intermediates were performed in solvent‐free conditions. Compounds 3 were prepared by hydrolysis of 1 . In respect of salicylamide moieties, binding affinities for 5‐HT 1A and 5‐HT 7 receptors increase according to the rank of derivatives 3 < 1 < 2 , for the same arylpiperazines. Regarding 5‐HT 2A receptors, increased activity of ligands was changed in reverse order to the affinity for 5‐HT 1A , i.e. 2 < 1 < 3 . 5‐HT 1A and 5‐HT 7 receptor binding constants were the highest for the 2‐methoxyphenyl ligand 2c , while the 3‐chlorophenyl ligand 3b was most active for 5‐HT 2A receptors.
Detection of Diabetic Foveal Edema (2004)

Agreement between contact lens examination and OCT for the detection of diabetic foveal edema is poor when OCT thickening is mild. This suggests that contact lens biomicroscopy is relatively insensitive for the detection of mild foveal thickening apparent on OCT. Additional studies are needed to investigate the natural course of cases with mildly increased foveal thickness on OCT that do not appear thickened clinically.
Specialized DNA Arrays for the Differentiation of Pancreatic Tumors (2005)

Our diagnostic approach resulted in 95% accurate differentiation between ductal adenocarcinomas and nonmalignant tumors of the pancreas. The diagnostic array, in conjunction with conventional diagnostic procedures, is thus suitable to significantly improve the reliability of pancreatic cancer diagnostics and can be expected to become a valuable new tool in the routine workup of suspect masses in the pancreas.
Adaptive multilevel classification and detection in multispectral images (1996)

MTL Systems, Inc.Imaging Technologies Division3481 Dayton-Xenia RoadDayton, Ohio 45432-2796Abstract. A novel multilevel adaptive pixel classiﬁcation and detection(AMLCD) method for detecting pixel and subpixel-size targets for multi-spectral images is presented. The AMLCD method takes into accountboth spectral and spatial characteristics of the data. In the ﬁrst level ofprocessing, the principal background end members are obtained usingthe K-means clustering method. Each pixel is examined next for classi-ﬁcation using a minimum-distance classiﬁer with the principal end mem-bers obtained in the previous level. In the second level, the neighbor-hood of each unclassiﬁed pixel is analyzed for inclusion of candidate endmembers in an unmixing procedure. If the list of candidate backgroundclasses is empty, the conditions for their inclusion are relaxed. The frac-tions of neighborhood and target signatures for the unclassiﬁed pixelsare determined by means of a linear least-squares method in the thirdlevel. If the results of unmixing are not satisfactory, the list of candidateclusters is renewed. Target detection within each pixel is performed next.The last processing level determines the size and location of detectedtargets with a clustering analysis methodology. Target size and locationare estimated on the basis of the sum and weighted vector mean, re-spectively, of the mixing fractions of the neighboring pixels. The AMLCDmethod was successfully applied to both synthetic and Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) hyperspectral imagery datasets.
Formaldehydderivate der Urethane (1903)

s das Rrasan entsteht.Der Nachweis des Naphtalinkerns i n diesen Umwandlungsproducten des Hamatoxylins bildet aber fiir die theoretischen Ableitungen von K o s t a n e c k i und L l o y d (13.d' ie vnrstehenden Mittheilungen) eine starke Stiitze.B e r n , Universitatslaboratorium.
Steady-state and fluorescence lifetime spectroscopy for identification and classification of bacterial pathogens (2014)

This study focuses on identification and classification of Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi and Klebsiella pneumoniae based on steady-state and fluorescence lifetime spectroscopy. Bacterial samples were cultured under c
G98-1356 Polyacrylamide – A Method to Reduce Soil Erosion (1998)

This NebGuide describes polyacrylamide, what it is, how it can be used to reduce soil erosion due to, irrigation and what water management changes must be considered. Topsoil loss can mean a long-term reduction in soil productivity, crop yield and the life expectancy of downstream storage reservoirs. In the short term, producers are faced with reuse pits to clean or a buildup of soil at the lower ends of fields which must be redistributed. Measures must be taken to reduce or eliminate soil erosion and sustain Nebraska's soil resource.
454. Aspects of stereochemistry. Part VI. Configuration of the 5-hydroxy-2-p-nitrophenyl-1,3-dioxans and further observations on trans-5-hydroxy-2-phenyl-1,3-dioxan (1961)

B. Dobinson and A. B. Foster, J. Chem. Soc., 1961, 2338 DOI: 10.1039/JR9610002338
Erythrocyte Fructose 2,6-Bisphosphate Content in Congenital Hemolytic Anemias (1991)

We have investigated the levels of fructose 2,6-bisphosphate and its synthesizing enzyme 6-phosphofructo-2-kinase in red blood cells from different congenital anemias. Fructose 2,6-bisphosphate concentration and 6-phosphofructo-2-kinase activity are markedly influenced by the number of reticulocytes in all the cases studied with the exception of homozygous pyruvate kinase deficiency, where no correlation was observed with the percentage of reticulocytes.
Is Taylor's Puzzle Genuine? (1956)

Is Taylor's Puzzle Genuine? Get access William Gerber William Gerber Washington Search for other works by this author on: Oxford Academic Google Scholar Analysis, Volume 17, Issue 1, October 1956, Pages 23–24, https://doi.org/10.1093/analys/17.1.23 Published: 01 October 1956
Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions (2013)

We identify novel candidate drug pairs for GBM and suggest possibilities to prospectively use transcriptional biomarkers to predict drug interactions in individual cases.
Resazurin Microtiter Assay Plate: Simple and Inexpensive Method for Detection of Drug Resistance in <i>Mycobacterium tuberculosis</i> (2002)

A method for detecting multidrug-resistant Mycobacterium tuberculosis by using a reduction of resazurin is described. Eighty clinical isolates were evaluated against isoniazid and rifampin; results at 7 days were compared with those of the proportion method. Specificity and sensitivity were excellent. The method is simple, inexpensive, and rapid and might be used with other antituberculosis drugs.
Human fetal central neurons in culture: voltage- and ligand-gated currents (1995)

1. The functional properties of sodium, potassium, calcium, N-methyl-D-aspartate (NMDA), kainate, and gamma-aminobutyric acid (GABA) currents were studied in dissociated monolayer cultures of fetal human brain neurons, using the whole cell patch-clamp technique. 2. Sodium currents were characterized with respect to the following properties: current density, voltage dependence of activation, voltage dependence of inactivation, and sensitivity to tetrodotoxin (TTX). All sodium currents exhibited voltage dependencies of activation and inactivation, and sensitivities to TTX that are characteristic of the neuronal form of the sodium current. 3. At least two types of potassium current were present, resembling the delayed rectifier and fast-inactivating potassium current. These two types of potassium current were distinguishable by their different kinetics, voltage dependencies of activation and inactivation, and sensitivities to 4-aminopyridine and tetraethylammonium. 4. High-voltage-activated calcium channel currents were present and were characterized with respect to current density, voltage dependencies of activation and inactivation, and sensitivity to cadmium. Low-voltage-activated calcium channel currents were also present. 5. NMDA- and kainate-gated currents were studied with respect to current density, time course, and current-voltage relationship. Kainate currents were also characterized with respect to inhibition by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX). In addition, NMDA and kainate responses were compared for cortical versus cerebellar neurons. NMDA responses, which are only found in neurons, were present, confirming the neuronal phenotype suggested by the presence of the neuronal form of the sodium current. Nondesensitizing kainate currents were also present, with a half-maximally effective concentration (EC50) of approximately 200 microM for kainate; CNQX inhibited the kainate current with a half-inactivating concentration of 0.55 microM. 6. GABA-gated currents were characterized with respect to current density, time course, receptor subtype, desensitization, dose response, current-voltage relationship, ionic selectivity, pharmacology, and potentiation by the neurosteroid 5 alpha-pregnan-3 alpha-ol-11,20-dione (alfaxalone). Desensitizing GABAA currents were selective for chloride, inhibited by bicuculline and tert-butyl-bicyclophosphorothionate, and potentiated by diazepam, pentobarbital sodium, and alfaxalone. The EC50 for GABA was 15 microM.
Deoxygenation of Exfoliated Graphite Oxide under Alkaline Conditions: A Green Route to Graphene Preparation (2008)

Stable graphene suspensions are prepared using a new, green, and intriguing synthetic route. Graphene can be directly prepared by the fast deoxygenation of exfoliated graphite oxide in strong alkaline solutions at low temperatures (50–90 °C), in the absence of reducing agents. This study opens an opportunity towards the production of processable graphene on an industrial scale. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Increasing incidence of clostridium difficile-associated diarrhea in African-American and Hispanic patients: association with the use of proton pump inhibitor therapy. (2007)

Our findings indicate that PPI may be an emerging and potentially modifiable risk factor for CDAD and point out the importance of vigilance in prescribing PPI, particularly to patients who are hospitalized, taking multiple antibiotics and suffering from multiple comorbidities.
A low-noise fast-settling PLL with extended loop bandwidth enhancement by new adaptation technique (2002)

A new adaptation scheme for low noise and fast settling phase locked loops (PLLs) is presented. Extended loop bandwidth enhancement is achieved by the adaptive control on the reference frequency and frequency divide ratio. It enables the loop bandwidth in the speed-up mode to greatly exceed the limit of approximately 1/10 of the channel spacing in the integer frequency synthesizer. Based on the proposed adaptation scheme, a 450 MHz frequency synthesizer with a 200 kHz channel spacing is implemented in 0.5 /spl mu/m CMOS process. In the speed-up mode, the loop bandwidth is enhanced by 16 times, resulting in a fast settling time of 260 /spl mu/s to within 20 kHz for a 72 MHz frequency step by simulation.
Applications of per-survivor processing to mobile digital communications (2002)

Applications of Per-Survivor Processing (PSP) to adaptive Maximum Likelihood Sequence Estimation (MLSE) and Reduced State Sequence Estimation (RSSE) are investigated in time-varying frequency-selective Rayleigh fading channels, which are typical of digital mobile communication systems. It is shown that the PSP characteristic of providing the channel estimators to the individual survivors with zero-delay, high-quality data-aiding sequences proves essential in a rapidly time-varying environment. We consider a Time-Division Multiple Access (TDMA) data frame where each user transmits a block of information symbols preceded by a known preamble and followed by a known tail. PSP-based adaptive RSSE decoders are shown to outperform conventional adaptive RSSE decoders of equivalent state complexity based on tentative decisions, when a rapidly varying channel is assumed. In addition, previous results on the need for an adaptive receiver in mobile applications are confirmed and the effect of not using a few known tail symbols is assessed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Microencapsulation of capsaicin by the complex coacervation of gelatin, acacia and tannins (2003)

Abstract With gelatin and acacia as walls and capsaicin as the core substance, microcapsules were prepared through the mixing of two solutions of oppositely charged polymers and were then treated with tannins. The processing factors included the stirring rate and the types and dosages of the surfactants used in the preparation of the microcapsules. The morphology and size distribution of the microcapsules were analyzed with optical microscopy, environmental scanning electron microscopy, and laser particle size analysis. The microcapsules had a mean diameter of 20–30 μm, a maximal drug loading content of 19.84%, and an encapsulation efficiency of 88.21% with a good dispersion, even distribution, and round shape. The influence of the tannins on the morphology and structures of the microcapsules was also investigated, and their interaction mechanism was examined. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 91: 2669–2675, 2004
Autonomous indoor wayfinding for individuals with cognitive impairments (2010)

Our findings suggest that the ability to adapt indoor wayfinding devices for appropriate timing of directions and standing orientation will be particularly important.
A Circulating-Foam Loop for Evaluating Foam at Conditions of Use (2005)

Summary Foam stability is an important parameter for foam fracturing. Bench-top testing is useful for screening but does not address the necessary conditions of temperature, pressure, pH [particularly with carbon dioxide (CO2) systems], and dynamic-flow conditions that can have unexpected influence on the foam's performance. A laboratory apparatus has been constructed for measuring the rheology of circulating-foam fluids to 400°F and 3,000 psi. The apparatus is equipped with a circulation pump, view cells, foam generator, mass flowmeter, and piping for loading a foam of the desired quality using either nitrogen (N2) or CO2. The foam rheometer is intended for evaluation of foam stability with time and comparison of various foam formulations for application in foam fracturing. The foam loop was designed to mimic shear rates found in a fracture or reservoir, which are typically 200 s−1 or less. The rheology is measured by monitoring the pressure drop across a 20-ft length of ¼-in. tubing maintained at temperature in an oven. Flow rate is continuously adjusted, to ensure a constant shear rate in the tubing, by the software using continuous mass-flowmeter input. Results relating to CO2 and N2 foams are discussed with emphasis on foam persistence, bubble size and population, and the rheological behavior with time. Temperature, pressure, and additives affect both foam texture and foam stability. The adoption of a standard technique patterned after this work for evaluating foam rheology could impact the use and development of foam fluids in the future.
Winner Trace Marking in Self-Organizing Neural Network for Classification (2008)

The classification for similar features classes is quite difficult task in many existing pattern-recognition systems. When the amount of samples is insufficient, neural networking training is hard. The dimension reduction, classification, clustering etc serial steps in recognition process takes such much time that the practical recognizing application is ease to meet the real time requirement. The new method is looking forward to. This paper presents a fast, simple and robust classifier, in which the winner has been traced and marked during entire training. We named it as Winner Trace Marking (WTM). The basic structure is based on self organizing feather map (SOFM), but the training and recognizing rules are changed and optimized. By WTM, a significant improvement is reached about above problems. The accuracy is highly increased with less time consumption. The experiment classifying strip surface defects by WTM are presented. The results are satisfactory.
Comparison of TNK With Wild-Type Tissue Plasminogen Activator in a Rabbit Embolic Stroke Model (2001)

TNK shows comparable rates of recanalization compared with wild-type tPA in a model of embolic stroke. While tPA increases hemorrhage rate, the hemorrhage associated with TNK treatment is not statistically different compared with controls or the tPA group. These findings suggest that TNK shows promise as an alternative thrombolytic treatment for stroke, but we could not demonstrate improved safety compared with wild-type tPA.
Aqueous Extract of Valerian Reduces Latency to Fall Asleep in Man (1985)

A group of 8 volunteers suffering from mild insomnia received a placebo, 450 mg or 900 mg of an aqueous extract of valerian root in a double-blind, repeated measures, random-order design. Subjective sleep ratings were assessed by questionnaire and movements were recorded throughout the night with wrist-worn activity meters. Using the first period of 5 consecutive minutes without movement as a criterion of sleep onset, there was a significant decrease in sleep latency with 450 mg valerian compared to placebo (15.8 ± 2.2 min vs 9.0 ± 1.5 min; paired "t" = 3.37;p < 0.01). The higher dose of valerian produced no further improvement in sleep latency.
Hide and Seek in the Peptidome (2003)

T cells of the adaptive immune system detect foreign pathogens by recognizing pathogen-derived peptides in a complex with MHC class I molecules presented on the surface of infected cells. In a Perspective, [Yewdell][1] discusses progress in understanding how cells generate peptides from cellular and viral proteins and the wily ways in which the Epstein Barr virus conceals its peptide products from the host immune system ([ Schwab et al .][2], [ Yin et al .][3]).

 [1]: http://www.sciencemag.org/cgi/content/full/301/5638/1334
 [2]: http://www.sciencemag.org/cgi/content/short/301/5638/1367
 [3]: http://www.sciencemag.org/cgi/content/short/301/5638/1371