gebhart/patrepeval huggingface dataset:
Effects of Prosthesis Mass on Hip Energetics, Prosthetic Knee Torque, and Prosthetic Knee Stiffness and Damping Parameters Required for Transfemoral Amputees to Walk With Normative Kinematics (2014)

We quantify how the hip energetics and knee torque required for an above-knee prosthesis user to walk with the kinematics of able-bodied humans vary with the inertial properties of the prosthesis. We also select and optimize passive mechanical components for a prosthetic knee to accurately reproduce the required knee torque. Previous theoretical studies have typically investigated the effects of prosthesis inertial properties on energetic parameters by modifying both mass and mass distribution of the prosthesis and computing kinetic and energetic parameters only during swing. Using inverse dynamics, we determined the effects of independently modifying mass and mass distribution of the prosthesis, and we computed parameters during both stance and swing. Results showed that reducing prosthesis mass significantly affected hip energetics, whereas reducing mass distribution did not. Reducing prosthesis mass to 25% of the mass of a physiological leg decreased peak stance hip power by 26%, average swing hip power by 74%, and absolute hip work over the gait cycle by 22%. Previous studies have also typically optimized prosthetic knee components to reproduce the knee torque generated by able-bodied humans walking with normative kinematics. However, because the prosthetic leg of an above-knee prosthesis user weighs significantly less than a physiological leg, the knee torque required for above-knee prosthesis users to walk with these kinematics may be significantly different. Again using inverse dynamics, it was found that changes in prosthesis mass and mass distribution significantly affected this required torque. Reducing the mass of the prosthesis to 25% of the mass of the physiological leg increased peak stance torque by 43% and decreased peak swing torque by 76%. The knee power required for an above-knee prosthesis user to walk with the kinematics of able-bodied humans was analyzed to select passive mechanical components for the prosthetic knee. The coefficients of the components were then optimized to replicate the torque required to walk with the kinematics of able-bodied humans. A prosthetic knee containing a single linear spring and two constant-force dampers was found to accurately replicate the targeted torque (R2=0.90 for a typical prosthesis). Optimal spring coefficients were found to be relatively insensitive to mass alterations of the prosthetic leg, but optimal damping coefficients were sensitive. In particular, as the masses of the segments of the prosthetic leg were altered between 25% and 100% of able-bodied values, the optimal damping coefficient of the second damper varied by 330%, with foot mass alterations having the greatest effect on its value.
SoftUDC: a software-based data center for utility computing (2004)

Utility computing aims to aggregate server, network, and storage systems into a single, centrally managed pool of resources. SoftUDC, a virtual machine monitor, lets applications and administrative domains share physical resources while maintaining full functional isolation.
Biologically Active Peptides Interacting with the G Protein-Coupled Formylpeptide Receptors (2007)

Leucocytes accumulate at sites of inflammation and microbial infection in response to locally produced chemotactic factors. N-formylpeptides produced by Gram negative bacteria were among the first chemotactic factors structurally defined which signal through G protein-coupled formylpeptide receptor (FPR) and FPR-like 1 (FPRL1) expressed by phagocytic leukocytes in human and in mouse homogogues mFPR and mFPR2. During the past few years, a number of pathogen- and host-derived agonists/antagonists for FPR, FPRL1 and another FPR variant FPR-like 2 (FPRL2) have been identified. Activation of formylpeptide receptors (FPRs) in phagocytic leukocytes by agonists results in increased cell chemotaxis, phagocytosis, and release of pro-inflammatory mediators. Peptide agonists for FPRs have also been shown to possess immune adjuvant activity when injected in mice. In addition, FPR aberrantly expressed on highly malignant human glioblastoma cells promotes tumor cell migration, proliferation and production of vascular endothelial growth factor in response to agonists released by necrotic tumor cells. Therefore, formylpeptide receptor ligands, by interacting with FPRs, play important roles in host defense and in the rapid progression of human glioblastoma.
Binder 2.0 - Reproducible, interactive, sharable environments for science at scale (2018)

Binder is an open source web service that lets users create sharable, interactive, reproducible environments in the cloud. It is powered by other core projects in the open source ecosystem, including JupyterHub and Kubernetes for managing cloud resources. Binder works with pre-existing workflows in the analytics community, aiming to create interactive versions of repositories that exist on sites like GitHub with minimal extra effort needed. This paper details several of the design decisions and goals that went into the development of the current generation of Binder.
ONE-TIME PAD CRYPTOGRAPHY (1996)

This paper shows how a moderate amount of random key stream can be used to generate a lifetime supply of keys for one-time pads. It further shows how arbitrarily many parties can correspond using the same random key, without compromising one another's communications. The net effect is to make the unbreakable one-time pad practical for widespread use.
Zur Relevanz wissenschafts-, medizin- und sozialgeschichtlicher Grundlagenforschung* (2013)

Aus Unkenntnis der eigenen methodischen Grundlagen und Beschränkungen überschreiten Wissenschaftler oft die legitimen Grenzen ihres Faches, wenn sie anderen Wissenschaften deren Wissenschaftlichkeit absprechen. Neue kritische Ansätze in den Natur-, Sozial- und Humanwissenschaften reflektieren hingegen vermehrt die Wechselwirkungen und Interdependenzen zwischen dem Forscher und seinem Fachgebiet bzw. dem Forschungsgegenstand und dem ihn selbst erst konstituierenden Rahmen. Aus der Wirtschaftswissenschaft kommt dabei die These, dass das moderne Subjekt und seine Rationalität auf Vergesellschaftungsprozessen in der Denkform des Geldes beruhen, die insofern auch massgeblich das Wesen der modernen Medizin bestimmen. Verglichen mit deren Prinzipien wie Quantifizierung, Standardisierung, Mathematisierung, Reproduzierbarkeit, Materialismus usw. erscheint die Homöopathie, die noch vor dem grossen Aufschwung der Geldwirtschaft im 19. Jahrhundert begründet wurde, als vom monetären Denken relativ freie, nämlich qualitative, individualisierende, hermeneutische und teleologische Medizin.
PROYECTO CREACION MUSICAL Y FUTURO (1977)

DENTRO DE LAS ACTIVIDADES DEL PROYECTO CREACION MUSICAL Y FUTURO, ORGANIZADO POR LA COORDINACION DE HUMANIDADES Y EL INSTITUTO DE INVESTIGACIONES ESTETICAS, SE LLEVARA A CABO LA CONFERENCIA FUTURO MUSICAL, MEMORIA Y OLVIDO, CON LA PARTICIPACION DE DANIEL CHARLES, PROFESOR DE LA UNIVERSIDAD DE PARIS. LA PONENCIA QUE VERSARA SOBRE LA LIBERACION DEL PENSAMIENTO MUSICAL A PARTIR DE LA MUSICA DE JOHN CAGE, SE VERIFICARA EL VIERNES 28 DE OCTUBRE EN LA TORRE DOS DE HUMANIDADES.
Kinetic control in catalytic olefin isomerization. An explanation for the apparent contrathermodynamic isomerization of 3-pentenenitrile (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetic control in catalytic olefin isomerization. An explanation for the apparent contrathermodynamic isomerization of 3-pentenenitrileRonald J. McKinneyCite this: Organometallics 1985, 4, 6, 1142–1143Publication Date (Print):June 1, 1985Publication History Published online1 May 2002Published inissue 1 June 1985https://pubs.acs.org/doi/10.1021/om00125a038https://doi.org/10.1021/om00125a038research-articleACS PublicationsRequest reuse permissionsArticle Views322Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Contributions of the Mitogen-activated Protein (MAP) Kinase Backbone and Phosphorylation Loop to MEK Specificity (1996)

To examine the specificity of MEKs for MAP kinase family members, we determined the abilities of several MEK isoforms to phosphorylate mutants of the MAP kinase ERK2 and the related kinase ERK3 which are modified in the phosphorylation loop. The ERK2 mutants included mutations of the two phosphorylation sites, mutations of the acidic residue between these two sites, and mutations that shorten the length of this loop. All mutants were tested for phosphorylation by six mammalian MEKs and compared with several wild type MAP kinases. MEK1 and MEK2 phosphorylate a majority of the ERK2 mutants. MEK2 but not MEK1 will phosphorylate ERK3. Alteration of the residue between the two phosphorylation sites neither dramatically affected the activity of MEK1 and MEK2 toward ERK2 nor conferred recognition by other MEKs. Likewise, reduction of the length of the phosphorylation loop only partially reduces recognition by MEK1 and MEK2 but does not promote recognition by other MEKs. Thus other yet to be identified factors must contribute to the specificity of MEK recognition of MAP kinases.
SYNTACTIC ANALYSIS OF TECHNICAL DRAWING DIMENSIONS (1994)

We present a syntactic approach to technical drawing dimensions analysis. A specific grammar is used to describe dimensions of drawings. This grammar can be graphically designed by combining different graphic primitives. The algorithm used for analysis can start at different points of the grammar. The analysis proceeds bottom-up and top-down according to previously obtained results.
HE4 as a biomarker for ovarian and endometrial cancer management (2009)

Ovarian and endometrial cancer will be diagnosed in over 63,000 women in 2009, resulting in 22,000 deaths in the USA. Histologic screening, such as pap smears for detection of cervical cancer, is not feasible for these diseases given difficulty with access to the tissue. Thus, a serum- screening test using a biomarker or panel of biomarkers would be useful to aid in cancer diagnosis, detection of recurrence and as a means to monitor response to therapy. In this review, we focus on the human epididymis protein (HE)4 gene, which appears to have potential as a biomarker for both of these diseases. The structure and methods of detection of HE4 are discussed. Preliminary data show that HE4 may have more potential than cancer antigen 125 in discriminating benign from cancerous ovarian masses, and has the strongest correlation with endometrial cancer of all markers tested to date. Utilizing risk stratification, a panel of biomarkers including HE4 may ultimately be useful for detecting ovarian and endometrial cancer at an early stage in patients at high risk.
Algorithmics: theory and practice (1989)

Algorithmics: theory and practice , Algorithmics: theory and practice , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
The Application of H-Phosphonate Chemistry in the HELP Synthesis of Oligonucleotides (1995)

Abstract The use of the H-phosphonate chemistry for its possible utilization in the liquid phase synthesis of oligonucleotides has been investigated.
Gyrodometry: a new method for combining data from gyros and odometry in mobile robots (2002)

This paper presents a very simple, yet very effective method for combining measurements from a gyro with measurements from wheel encoders (odometry). The method, called gyrodometry, has been developed based on a careful study of the physical interaction between the ground and the vehicle. We present experimental evidence that non-systematic odometry error sources (such as bumps) impact the vehicle only during very short periods; typically a fraction of a second for each encounter. During these short instances the readings from the gyro and from odometry differ significantly, while in the absence of large non-systematic errors the readings are very similar. Gyrodometry makes use of this observation by using odometry data only-most of the time, while substituting gyro data only during those brief instances during which the gyro and odometry data differ substantially. In this way the ill-effects of gyro drift are almost completely eliminated, and our method can thus make use of inexpensive gyros with large drift rates. Experimental data is presented that demonstrates the effectiveness of this approach.
Physical and Mechanical Properties of Pinecone Scale Fiber/Vigna Mungo Powder Reinforced Polypropylene Based Hybrid Composites (2022)

This study accounted for fabrication, physico-mechanical, and morphological properties of extracted pine cone scale fiber (natural fiber) and vigna mungo powder (natural filler) reinforced polypropylene composite using the compression molding technique. The behavior of hybrid composites was examined through tensile, flexural, hardness, impact, and SEM characterizations. Compared to the neat polymer matrix, the mechanical properties of the hybrid composites improved. The flexural and hardness properties where significantly enhanced with the addition of Vigna mungo powder. The hybrid composite C2 (30% pine cone scale fiber reinforcement) showed the highest density tensile and impact strength. The composite C5 (30% vigna mungo powder reinforcement) showed the least density, lowest impact, and high flexural strength. This was attributed to the chemical treatment of the fibers, which improved the fibers’ tensile properties due to the removal of the wax layer from fiber surface. The study concluded that naturally occurring pine cone scale fiber and vigna mungo powder could be used as potential reinforcements and can be a viable alternative material for polymer-based composites.
γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization (2010)

DNA double-strand breaks (DSBs) represent an important radiation-induced lesion and impaired DSB repair provides the best available correlation with radiosensitivity. Physical techniques for monitoring DSB repair require high, non-physiological doses and cannot reliably detect subtle defects. One outcome from extensive research into the DNA damage response is the observation that H2AX, a variant form of the histone H2A, undergoes extensive phosphorylation at the DSB, creating gammaH2AX foci that can be visualized by immunofluorescence. There is a close correlation between gammaH2AX foci and DSB numbers and between the rate of foci loss and DSB repair, providing a sensitive assay to monitor DSB repair in individual cells using physiological doses. However, gammaH2AX formation can occur at single-stranded DNA regions which arise during replication or repair and thus does not solely correlate with DSB formation. Here, we present and discuss evidence that following exposure to ionizing radiation, gammaH2AX foci analysis can provide a sensitive monitor of DSB formation and repair and describe techniques to optimize the analysis. We discuss the limitations and benefits of the technique, enabling the procedure to be optimally exploited but not misused.
Investigation on COS Hydrolysis over TiO2 Alumina Catalyst (2008)

The impetus to reduce the emission of sulfur-containing compounds into the environment has become increasingly important in recent years. COS as the main organic sulfur compounds from synthesis gas can be removed by catalytic hydrolysis. A serious of catalyst samples for COS hydrolysis was prepared by dry-mixing technique using K <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> as a active component mixing TiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> with pseudo-boehmite. The property of K <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> /TiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> catalyst for COS hydrolysis is characterized by activity evaluation, FT-IR and surface basicity measurement. It is found that the activity of COS hydrolysis have not been influenced by additive of TiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> over alumina catalyst. But the rate of H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> S desorption from the catalyst surface have increased, thus to reduce the reaction of adsorbed H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> S on surface with O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , the K <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> /TiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> catalyst has ability of anti-sulfur poisoning.
An actively balanced GaAs HBT-Schottky mixer for 3-V wireless applications (1997)

Here we present a novel low-voltage active mixer topology which enables 3-V double-balanced active mixer operation from wide-bandgap GaAs-based heterojunction bipolar transistors (HBTs). The compact mixer design integrates directly coupled active radio frequency (RF) and local oscillator (LO) transformer baluns with a Schottky-diode ring-quad to form a double-balanced mixer which operates from DC to 5 GHz. Biased with a low 3-V supply and operated as a down-converter with a fixed LO at 800 MHz and 0 dBm, the mixer achieves 9.4-dB conversion gain (CG) at 1 GHz with positive CG out to 4 GHz and an IP3 of -5 dBm. The LO-IF isolation is >20 dB while the 2-2 spur suppression is >20 dB over a broad 1-5 GHz RF input band. The novel 2.1/spl middot/V/sub BE/ supply design topology allows 3-V operation from the high turn-on voltage GaAs HBT's, making them suitable for portable wireless applications, and can enable 1.5-V operation for Si, Si-Ge, and InP BJT/HBT technologies.
The Mythical Man-Month: After 20 years (1995)

The plane droned through the night toward LaGuardia. Clouds and darkness veiled all interesting sights. The document I was studying was pedestrian. I was not, however, bored. The stranger sitting next to me was reading The Mythical Man-Month, and I was waiting to see if by word or sign he would react. Finally as we taxied toward the gate, I could wait no longer: "How is that book? Do you recommend it?" “Hmph! Nothing in it I didn’t know already.”
Plasmonic aerosols (2019)

Plasmonic nanoparticles resonantly couple to and confine light below the diffraction limit. This mechanism has enabled a modern renaissance in optical materials, with potential applications ranging from sensing and circuitry to renewable energies and medicines. However, these plasmonic materials are typically constrained to dilute liquids or solid two-dimensional surfaces, thereby limiting their possibilities. Here, we experimentally demonstrate a plasmonic aerosol by transitioning liquid suspensions of gold nanorods into the gas phase and simultaneously measuring their optical spectra. By measuring and modeling the evolution of the longitudinal absorbance peak of the nanorods from the liquid to the gas phase, we find that the aerosols are optically homogeneous and thermodynamically stable. We show that by tailoring the aspect ratio of the nanorods, the aerosol absorbance peak is tunable from visible to midwave infrared wavelengths. We find the sensitivity of the absorbance peak wavelength to changes in the refractive index of the gas depends linearly on the aspect ratio and can be estimated from the geometric and material properties of the nanorod. For high aspect ratio nanorods the sensitivity becomes extremely large, which may be useful in aiding geoengineering challenges. This work establishes plasmonic aerosols, potentially enabling exciting opportunities for fundamental and applied research.
Magnetic resonance imaging: effects of magnetic field strength. (1984)

Magnetic resonance images of the head, abdomen, and pelvis of normal adult men were obtained using varying magnetic field strength, and measurements of T1 and T2 relaxations and of signal-to-noise (SN) ratios were determined. The T1 relaxation of gray matter, white matter, and muscle increases and T2 decreases with field strength, while T1 of fat remains relatively constant and T2 increases. As a consequence, for any one spin echo sequence, gray/white matter contrast decreases and muscle/fat contrast increases with field. SN levels rise rapidly up to 3.0 kgauss and then change more slowly, actually dropping for muscle. The optimum field for magnetic resonance imaging depends on tissue type, body part, and imaging sequence, so that it does not have a unique value. Magnetic resonance systems that operate in the 3.0-5.0 kgauss range achieve most or all of the gains that can be achieved by higher magnetic fields.
Electric field tuning of the band gap in graphene multilayers (2009)

A perpendicular electric field applied to multilayers of graphene modifies the electronic structure near the $K$ point and may induce an energy gap in the electronic spectrum. This gap is tunable by the gate voltage and its size depends on the number of layers. We use a tight-binding approach to calculate the band structure and include a self-consistent calculation in order to obtain the density of charge carriers. Results are presented for systems consisting of three and four layers of graphene. The effect of the circular asymmetry of the band structure on the gap is critically examined.