gebhart/patrepeval huggingface dataset:
The content and composition of sterols and sterol esters in low erucic acid rapeseed (<i>Brassica napus</i>) (1978)

The low temperature crystallization technique for the enrichment of "minor" components, such as sterols and sterol esters, from vegetable oils was applied to low erucic acid rapeseed oils. The recovery of free sterols and sterol esters was estimated by use of(14)C-cholesterol and(14)C-cholesterol oleate. 80% of the free sterols and 45% of the sterol esters were recovered in the liquid fraction, while in two studies total recoveries were 95% and 99%, respectively. This technique showed some selectivity toward the sterol bound fatty acids when compared to direct preparative thin layer chromatography (TLC) of the crude oil. Gas liquid chromatography (GLC) analysis of the free and esterified sterols as TMS-derivatives showed very little selectivity in the enrichment procedure. The fatty acid patterns of the sterol esters demonstrated, however, a preference in the liquid fraction for those sterol esters which have a high linoleic and linolenic acid content. The content of free sterols was 0.3-0.4% and that of sterol esters 0.7-1.2% of the rapeseed oils in both winter and summer types of low erucic acid rapeseed (Brassica napus) when the lipid classes were isolated by direct preparative TLC of the oils. The free sterols in the seven cultivars or breeding lines analyzed were composed of 44-55% sitosterol, 27-36% campesterol, 17-21% brassicasterol, and a trace of cholesterol. The esterified sterols were 47-57% sitosterol, 36-44% campesterol, 6-9% brassicasterol, and traces of cholesterol and Δ5-avenasterol. The fatty acid patterns of these esters were characterized by ca. 30% oleic acid and ca. 50% linoleic acid, whereas these acids constitute 60% and 20%, respectively, of the total fatty acids in the oil. Little or no variation in sterol and sterol ester patterns with locality within Sweden was observed for the one cultivar of summer rapeseed investigated by the low temperature crystallization technique.
Ring‐Opening Metathesis Polymerization of Biomass‐Derived Levoglucosenol (2019)

The readily available cellulose-derived bicyclic compound levoglucosenol was polymerized through ring-opening metathesis polymerization (ROMP) to yield polylevoglucosenol as a novel type of biomass-derived thermoplastic polyacetal, which, unlike polysaccharides, contains cyclic as well as linear segments in its main chain. High-molar-mass polyacetals with apparent weight-average molar masses of up to 100 kg mol<sup>-1</sup> and dispersities of approximately 2 were produced despite the non-living/controlled character of the polymerization due to irreversible deactivation or termination of the catalyst/active chain ends. The resulting highly functionalized polyacetals are glassy in bulk with a glass transition temperature of around 100 °C. In analogy to polysaccharides, polylevoglucosenol degrades slowly in an acidic environment.
Incomplete chimerism in erythroid, myeloid and B lymphocyte lineage after T cell-depleted allogeneic bone marrow transplantation. (1988)

In 22 transplant patients who received T cell-depleted allogeneic bone marrow (alloBMT) we investigated the chimeric state using a mixed agglutination technique and isoenzyme determinations for the red cell lineage, an isoenzyme assay for the myeloid cells, immunoglobulin allotyping for B lymphocytes and cytogenetics for karyotyping. The median duration of follow-up for these patients was 25 months after BMT. Chimerism was evaluated after 6 months. In 14 (64%) of the 22 patients incomplete chimerism was found when the results of the different techniques were combined. Recipient type cells were detected in the red cell lineage in 36% of cases, recipient type myeloid cells in 7% of cases and recipient type mitotic cells in 25% of cases where the marker could provide discrimination. In 100% of the evaluable patients recipient type immunoglobulins persisted after BMT. The data indicate a high frequency of incomplete chimerism following T cell-depleted BMT which involved the broad series of hematological lineages. This frequency appears higher than that following non-T cell-depleted BMT.
Complement activation during storage of blood under normal blood bank conditions. Effects of proteinase inhibitors and leukocyte depletion (1992)

During storage of CPD-A1 preserved whole blood factors of the complement cascade become activated, as evidenced by a rapid increase in the concentrations of C3a-desArg and C4a-desArg. After 10 to 14 days of whole blood storage, the elevations of C3a and C4a levels were highly significant. This increase was paralleled by an increase in the concentration of the lysosomal proteinase elastase from polymorphonuclear (PMN) granulocytes. By contrast, the concentration of the C3 activator complex C4b2b remained unchanged even after 3 weeks of storage. The supplementation of the anticoagulant CPD-A1 with the polyvalent-proteinase-inhibitor aprotinin and the specific elastase- inhibitor eglin C failed to inhibit complement activation, whereas leukocyte depletion could partially abolish the increase of the concentration of C4a, but had no effect on C3a concentrations. These observations support the notion that cleavage of C4 during storage of whole blood is partially leukocyte dependent, whereas the activation of C3 is possibly caused by the activation of the alternate pathway of the complement system by contact of plasma with plastic surfaces.
Motion estimation using 3-D infinite frequency resolution analysis (2010)

The spatiotemporal spectra of a movie that contains a moving object form a plane in the three-dimensional (3-D) frequency domain. This plane, which is referred to as the theoretical motion plane, reflects the velocity and calculating the slope of the moving objects. However, if the resolution of the frequency analysis method is not high enough to obtain the actual spectra from the objective signal, the spatiotemporal spectra disperse away from the theoretical motion plane. In the present paper, we propose a infinite frequency resolution method, referred to as three-dimensional (3-D) Non-harmonic analysis (NHA), which is only weakly influenced by the analysis window. In addition, we estimate the motion vectors of objects in a movie using the clustering method in conjunction with the least squares method (LSM) for the spatiotemporal spectrum of 3-D NHA.
A Constitutively Active Version of the Ser/Thr Kinase Akt Induces Production of the obGene Product, Leptin, in 3T3-L1 Adipocytes (1997)

The expression of the ob gene product leptin in adipose tissues has been previously described to be regulated by insulin in vivo and vitro. Akt, a ser/thr kinase with a pleckstrin homology domain, has recently been identified to function in the insulin receptor signaling cascade. The aim of this study was to investigate the role of Akt in the production of leptin by adipocytes. Therefore, we examined leptin production by 3T3-L1 adipocytes stably expressing a myristoylated version of Akt which is constitutively active. Leptin levels in the supernatants of serum starved, nonstimulated 3T3-L1 adipocytes were determined by radioimmunoassay (RIA). Expression of the constitutively active Akt was found to induce a more than 20-fold increase in leptin levels whereas a control non-myristoylated Akt had no effect. Leptin mRNA levels as determined by either RNase protection assay or reverse transcriptase (RT)-polymerase chain reaction (PCR) were not elevated by the constitutively active Akt. These results indicate that Akt can induce leptin production in 3T3-L1 adipocytes via a non-transcriptional mechanism.
Optimizing a Battery Energy Storage System for Primary Frequency Control (2007)

This paper presents a method for the dimensioning of a battery energy storage system (BESS) to provide a primary frequency reserve. Numerical simulations based on historic frequency measurements are used to determine the minimum possible capacity, i.e., the lowest possible cost, which fulfills the technical requirements of the grid code. We implement a novel control algorithm with adjustable state of charge limits and the application of emergency resistors. At current European market prices, an optimized lead-acid BESS can be a profitable utility solution for the primary frequency control.
Detection of heterozygous deletions and duplications in the MECP2 gene in Rett syndrome by Robust Dosage PCR (RD-PCR) (2005)

Fifty to eighty percent of Rett syndrome (RTT) cases have point mutations in the gene encoding methyl-CpG-binding protein-2 (MECP2). A fraction of MECP2 negative classical RTT patients has large heterozygous deletions. Robust Dosage PCR (RD-PCR) assays were developed as a rapid, convenient and accurate method to detect large heterozygous deletions and duplications. A blinded analysis was performed for 65 RTT cases from Portugal by RD-PCR in the coding exons 2-4 of the MECP2 gene. Neither the patients with point mutations nor the non-classical RTT patients without point mutation had a deletion or duplication. One of remaining eight female patients with classical RTT without point mutation had a heterozygous deletion. This is the first report of a deletion spanning the entire MECP2 gene. The deletion was confirmed by Southern blotting analysis and the deletion junction was localized 37 kb upstream from exon 1 and 18 kb downstream from exon 4. No duplications were detected. Our results suggest that RD-PCR is an accurate and convenient molecular diagnostic method.
Routes to <i>N</i>,<i>N</i>‘-Unsymmetrically Substituted 1,3-Diketimines (2005)

[reaction: see text] A series of novel N,N'-unsymmetrically substituted 1,3-diketimines (3, 12, and 27) have been synthesized from the reaction of exocyclic enaminoketones 8 with amines or metalloenamines (from 13 or 14) with imidoyl thioether 25 or 26.
The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research (1999)

The discovery of glycosylphosphatidylinositol (GPI) membrane anchors has had a significant impact on several areas of eukaryote cell biology. Studies of the African trypanosome, which expresses a dense surface coat of GPI-anchored variant surface glycoprotein, have played important roles in establishing the general structure of GPI membrane anchors and in delineating the pathway of GPI biosynthesis. The major cell-surface molecules of related parasites are also rich in GPI-anchored glycoproteins and/or GPI-related glycophospholipids, and differences in substrate specificity between enzymes of trypanosomal and mammalian GPI biosynthesis may have potential for the development of anti-parasite therapies. Apart from providing stable membrane anchorage, GPI anchors have been implicated in the sequestration of GPI-anchored proteins into specialised membrane microdomains, known as lipid rafts, and in signal transduction events.
Diborane as a Mild Reducing Agent for the Conversion of Primary, Secondary, and Tertiary Amides into the Corresponding Amines (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiborane as a Mild Reducing Agent for the Conversion of Primary, Secondary, and Tertiary Amides into the Corresponding AminesHerbert C. Brown and Peter. HeimCite this: J. Am. Chem. Soc. 1964, 86, 17, 3566–3567Publication Date (Print):September 1, 1964Publication History Published online1 May 2002Published inissue 1 September 1964https://pubs.acs.org/doi/10.1021/ja01071a037https://doi.org/10.1021/ja01071a037research-articleACS PublicationsRequest reuse permissionsArticle Views1568Altmetric-Citations90LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Ion-Exchange Chromatography of Free Amino Acids in Human Intraocular Fluids (1971)

Abstract Free amino acids were determined in human aqueous, vitreous, and subretinal fluid (50 to 100 µl) from individual eyes by using an ion-exchange chromatographic technique of increased sensitivity. The concentrations of amino acids in aqueous fluid from intraocular malignant melanomas were compared with those found for normal eyes, and some differences were observed. Other pathological conditions investigated were mongolism, intraocular hemangioma, uveitis, Sturge—Weber’s syndrome, and Marfan’s syndrome; only the latter two appeared to have a normal amino acid pattern. Vitreous and subretinal fluid each had a distinctive pattern, with the amino acid concentrations generally lower than in aqueous fluid, except for glutamine, which appeared to be of the same order of magnitude in all intraocular fluids and plasma. Postmortem and eye-bank aqueous fluids were also analyzed, and showed considerable variability from normal. The presence of an additional 28 unknown compounds was demonstrated in aqueous fluid.
Multiple-polynomial LFSR based pseudorandom number generator for EPC Gen2 RFID tags (2011)

We present a lightweight pseudorandom number generator (PRNG) design for EPC Gen2 RFID tags. It is based on a linear feedback shift register (LFSR) configured with multiple feedback polynomials that are selected by a physical source of randomness. The proposal successfully handles the inherent linearity of LFSR based PRNGs and satisfies the statistical requirements imposed by the EPC Gen2 standard. Statistical analysis of the sequences generated by our generator confirms the validity of the proposed technique.We show that our proposal has, moreover, a simpler hardware implementation and energy consumption than previous designs reported in the literature.
An Attempt to Improve Bilateral Cochlear Implants by Increasing the Distance between Electrodes and Providing Complementary Information to the Two Ears (2010)

Data from this study indicate that some adult bilateral cochlear implant recipients can benefit from using a speech processing strategy in which the input spectrum is interleaved among electrodes across the two implants. It is possible that the subjects in this study who showed a significant improvement with the interleaved strategy did so because of less channel interaction; however, this hypothesis was not directly tested.
AUTOGENOUS FREE GRAFTS OF SKELETAL MUSCLE (1971)

From the Department of Plastic Surgery and the Institute of Clinical Research of the Middlesex Hospital, London, and from the Plastic Surgery Centre of the Mount Vernon Hospital, Northwood, Middlesex
Phase separation in incompatible polymer blends: polypropylene-polyethylene system (2007)

The morphology of polypropylene-polyethylene blends has been investigated in the as-prepared state by employing interface distribution functions to evaluate their small angle X-ray scattering. While the morphology of the PP (within the investigated composition range) is not altered by the presence of finely dispersed PE, the morphology of the PE component is strongly dependent on composition. Below a PE weight fraction of 0.3 the PE crystal thickness increases with increasing PE content. Concurrently the lattice distortion decreases.
A palladium-catalyzed coupling reaction and a photolytic reaction for the direct synthesis of 5-arylpyrimidine nucleotides (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA palladium-catalyzed coupling reaction and a photolytic reaction for the direct synthesis of 5-arylpyrimidine nucleotidesChristopher F. Bigge and Mathias P. MertesCite this: J. Org. Chem. 1981, 46, 10, 1994–1997Publication Date (Print):May 1, 1981Publication History Published online1 May 2002Published inissue 1 May 1981https://pubs.acs.org/doi/10.1021/jo00323a005https://doi.org/10.1021/jo00323a005research-articleACS PublicationsRequest reuse permissionsArticle Views159Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The fast cooling/heating rate effects in devitrification of glasses. II. Crystallization kinetics (1998)

An analytical description of devitrification kinetics induced by time-dependent nucleation and growth of crystallites during a quench-heating cycle is proposed. Relevant experimental situations include differential thermal analysis (DTA) or differential scanning calorimetry (DSC). The proposed description involves very few assumptions regarding the temperature dependence of various kinetic parameters, but rather employs measured values of growth rates. It is shown that the conventional description of nucleation based on the steady-state approximation, as a rule, is inapplicable for the description of the DTA/DSC experiment for experimentally reasonable quench/heating rates. The latter is confirmed by the analysis of available experimental data on o-terphenyl and lithium disilicate.
CD40 Ligand Mediates Inflammation Independently of CD40 by Interaction With Mac-1 (2007)

These observations identify the interaction of CD40L and Mac-1 as an alternative pathway for CD40L-mediated inflammation. This novel mechanism expands understanding of inflammatory signaling during atherogenesis.
Host measurement of network traffic (2007)

In modern passive network measurement, flow-based analyses have been widely used. In this paper, we regard dasiahostspsila as aggregations of flows, and investigate host rather than flow-based measurements. We show that analyzing host behaviors contribute significantly to better understanding of network behavior, thus it is a feasible study that should be of interest to both researchers and network operators. By empirically exploring two university edge networks, our findings suggest that up to 40% of the unique hosts re-enters the network, and many of those tend to do so within three hours. Furthermore, at least 20% of all hosts are active for between 0.1s and 10s, and only a quarter of the hosts stay in the network for more than 10s. Additionally, many hosts are identified as abnormal, producing many flows despite being short-lived. Lastly, we examine the correlations between numerous host attributes to find relationships; for instance, host size and size-rate are highly positive-correlated.
Randomized Clinical Trial of the Iron-Based Phosphate Binder PA21 in Hemodialysis Patients (2012)

PA21 5-12.5 g/d significantly reduces serum phosphorus in hemodialysis patients. The 5 g/d and 7.5 g/d dosages showed similar efficacy to 4.8 g/d of sevelamer-HCl. The adverse events rate was similar for PA21 and sevelamer-HCl.
Synthesis of haptens and conjugates for an enzyme immunoassay for analysis of the herbicide bromacil (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of haptens and conjugates for an enzyme immunoassay for analysis of the herbicide bromacilFerenc. Szurdoki, Hassan K. M. Bekheit, Maria Pilar. Marco, Marvin H. Goodrow, and Bruce D. HammockCite this: J. Agric. Food Chem. 1992, 40, 8, 1459–1465Publication Date (Print):August 1, 1992Publication History Published online1 May 2002Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/jf00020a034https://doi.org/10.1021/jf00020a034research-articleACS PublicationsRequest reuse permissionsArticle Views181Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
14q32 translocations are associated with mixed-lineage expression in childhood acute leukemia (1990)

The frequency and characteristics of childhood acute leukemia with a 14q32 translocation [other than the t(8;14)(q24;q32)] were determined in 335 cases of newly diagnosed acute lymphoblastic leukemia (ALL) and 105 cases of acute nonlymphoblastic leukemia (ANLL). Ten children, representing 2.3% of the entire cohort, had this abnormality (1.5% of ALL patients and 4.8% of ANLL patients). By French-American-British (FAB) criteria, 4 cases were classified as L1, 1 as L2, 2 as M1, 1 as M2, and 2 as M5. Remarkably, mixed-lineage expression was found in 6 of these 10 cases, but in only 21 of the other 430 cases without a 14q32 translocation (P less than .001). Leukemic cells from 5 of these 6 cases (4 ANLL, and 1 ALL) coexpressed CD13, a myeloid-associated antigen, and CD2, a T-cell-associated antigen; blasts from the sixth case (ALL) coexpressed CD13 and CD19, a B-lineage-associated antigen. Thus, in addition to the well-described 11q23 translocations and t(9;22), 14q32 translocations also appear to be associated with mixed lineage antigen expression. Break-points of the reciprocal chromosomes from chromosome 14 were identified in five of these cases: 1q23, 6q23- q25, 7p15, 8q11, and 12q13. Of the four mixed-lineage cases that were tested, none showed rearrangement of the immunoglobulin heavy chain (IgH) gene. This suggests that the 14q32 breakpoint does not involve the IgH gene and that an unidentified important gene may reside on 14q32.