gebhart/patrepeval huggingface dataset:
Facile Bifunctional Addition of Lactones and Esters at Low Temperatures. The First Intermediates in Lactone/Ester Hydrogenations (2009)

The bifunctional addition of lactones/esters is unexpectedly facile at low temperatures. Catalytic hydrogenations of esters can be carried out under mild conditions, e.g. −20 °C under 4 atm of H2, but product inhibition slows these reactions over time.
IMITATOR: A deterministic multicore replay system with refining techniques (2012)

Developing parallel programs imposes many debugging challenges on multicore systems. Many researchers were successful to detect parallel faults in background by hardware assistance. However, it is still an urgent issue to reproduce the same faulted circumstance after faults occurred. Tracing the causality between events is a popular solution in current multicore systems, but it is limited by onchip storage and tracing bandwidth. As a result, an intelligent record and replay system is the key to the future multicore debugging problems. This paper proposes IMITATOR for both trace compression and deterministic replay. In contrast to the most other record and replay systems, IMITATOR presents an additional phase, refining phase, between record and replay phases to significantly reduce the recorder overhead, while enabling faster replaying. Results with SPLASH2 benchmark on a 32-core system show that IMITATOR can (a) significantly reduce trace size by the trace refining techniques (∼16% of native trace) and (b) achieve replay speed 1.96 times faster than the replayer using Sigrace scheme on average.
A Latex Agglutination Test for Measuring Antibodies to Streptococcal Mucopeptides (1973)

Abstract The preparation and application of mucopeptide (MP)-coated latex particles for determining antibody to streptococcal group A MP is described. Anti-MP hyperimmune sera, normal animal and human sera, and commercial antisera to various antigens were tested. MP-latex agglutination proved to be both specific and highly sensitive, permitting the detection of low antibody levels in 20 to 40% of normal sera; these antibodies were not demonstrable by means of other serologic techniques. Data confirming the specificity of the reaction are presented. No cross-agglutinations were observed with the exception of commercial anti-C reactive protein (CRP) serum. This latter phenomenon may be due to traces of MP present in the preparations used to produce anti-CRP serum. Latex agglutination should prove useful for establishing the occurrence of anti-MP antibody and for elucidating the role of anti-MP antibody in the various toxic or inflammatory reactions induced by MP in vitro and in vivo.
Probiotics for treating acute infectious diarrhoea (2010)

Probiotics probably make little or no difference to the number of people who have diarrhoea lasting 48 hours or longer, and we are uncertain whether probiotics reduce the duration of diarrhoea. This analysis is based on large trials with low risk of bias.
Nano-Sized Inverted Domain Formation in Stoichiometric LiTaO 3 Single Crystal Using Scanning Nonlinear Dielectric Microscopy (2002)

Scanning Nonlinear Dielectric Microscopy (SNDM) is the method for observing ferroelectric polarization distribution, and now, its resolution has become to the sub-nanometer order. Up to now, we have studied high-density ferroelectric data storage using this microscope. In this study, we selected stoichiometric LiTaO 3 (SLT) single crystals as ferroelectric recording media. At first, we studied polarization inversion characteristics in detail, and as a result, we achieved forming small inverted domain with the radius of 6 nm. And we also studied the retention of inverted domain. Moreover, in a recent study, we have also formed inverted domain in congruent LiTaO 3 (CLT) single crystal, and, as a result, we achieved high-density data storage in excess of 1 Tbit/inch 2.
Self-Folding Origami Using Torsion Shape Memory Alloy Wire Actuators (2014)

Self-folding origami requires a low-profile actuator to be embedded in a sheet of paper-like planar material. Various actuation methods have been employed to actively fold such sheets. This paper presents a torsion shape-memory alloy (SMA) wire actuator embedded in patterned origami structures that actively folds the origami by twisting the SMA wire. A simple wire is aligned with the fold line, and each end is fixed to a facet. The twisting of the wire directly rotates the facets. This method has the advantage of using an easily available wire SMA and the advantage of a flat form factor similar to that of sheet SMA. Generally, SMA wire is used in a linear manner or as a spring. The torsion SMA wire presented in this paper is trained to generate torsional force when heated. The amount of rotation depends on the length of the wire; a 200-μm-diameter SMA wire 12 mm in length can induce 540° rotation. SMA wires are arranged in pairs side by side to rotate the facets in both directions. Maximum torque of 70 mNcm is generated in this antagonistic arrangement. The torsion SMA wire actuators enable a novel design for a programmable folding sheet that is easily manufactured and exhibits fast folding and unfolding.
Binding specificity of the two major DNA-binding proteins in human serum. (1979)

The two major DNA-binding proteins of human serum (DNA-binding protein 1 and DNA-binding protein 2) were shown to bind preferentially to single-stranded polynucleotides rich in guanine residues. Equilibrium competition experiments using a nitrocellulose filter assay system containing labeled human lymphocyte DNA and various competing natural and synthetic polynucleotides indicated that both proteins recognized sequences of bases containing a keto group in either position 6 (purines) or 4 (pyrimidines) and that these keto groups must be readily accessible for effective binding to occur. Guanine was shown to be the preferred nucleotide through inhibition experiments using a series of synthetic homopolymers and a series of bacterial DNAs of differing G + C content. The relationship between protein affinity and G + C content was shown to be directly proportional. The equilibrium constants for the binding of the human lymphocyte DNA by both proteins were on the order of 10(-6) M, and the length of the nucleotide sequence necessary for effective binding was found to be 12 to 18 bases using a series of oligomers of poly(dG).
Determination of tube‐wave to body‐wave ratio for Conoco borehole orbital source (1999)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1999Determination of tube‐wave to body‐wave ratio for Conoco borehole orbital sourceAuthors: Anton ZiolkowskiZander SneddonLarry WalterAnton ZiolkowskiUniversity of Edinburgh, Zander SneddonUniversity of Edinburgh, and Larry WalterOyo Instruments Inc.https://doi.org/10.1190/1.1820824 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1820824FiguresReferencesRelatedDetailsCited ByDipole and monopole actuator for underground applicationReview of vibroseis data acquisition and processing for better amplitudes: adjusting the sweep and deconvolving for the time-derivative of the true groundforceGeophysical Prospecting, Vol. 58, No. 1Tube‐wave suppression in single‐well seismic acquisitionThomas M. Daley, Roland Gritto, Ernest L. Majer, and Phillip West29 May 2003 | GEOPHYSICS, Vol. 68, No. 3 SEG Technical Program Expanded Abstracts 1999ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1999 Pages: 2061 publication data© 1999 Copyright © 1999 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 04 Jan 2005 CITATION INFORMATION Anton Ziolkowski, Zander Sneddon, and Larry Walter, (1999), "Determination of tube‐wave to body‐wave ratio for Conoco borehole orbital source," SEG Technical Program Expanded Abstracts : 156-159. https://doi.org/10.1190/1.1820824 Plain-Language Summary PDF DownloadLoading ...
Molecular and Nanoparticles vapor deposition methods to create super hydro/oleophobic surfaces (2014)

In this paper, glassslide surfaces were functionalized using nanoparticles vapor deposition (NVD) and molecular vapor deposition (MVD) techniques. The NVD technique allowed the deposition of aluminum oxide (Al2O3) nanoparticles on the surface. The MVDtechnique allowed the deposition of a thin layer of (Tridecafluoro-1,1,2,2,-tetrahydrooctyl)trichlorosilane (FOTS). Nanoparticles deposition increased the surface roughness, leading to higher contact angles when compared to surfaces treated with only FOTS.Fourier Transform Infrared spectra showed the presence of peaks corresponding to fluorocarbon chains and Al2O3on the functionalized surfaces. Dynamic contact angles of aqueous and organic solutions were measured in order to assess hydrophobic/oleophobic properties. The surface free energies of the samples were calculated using different methods. Dynamic contact angles higher than 150º were obtained for water and other organic liquids for functionalized samples. In addition,glass slides treated with Al2O3nanoparticles followed byFOTS layer showed low hysteresis when performing advancing and receding contact angles with water and hexadecane, thus,indicating super hydro/oleophobic properties.
Focusing Nanocrystal Size Distributions via Production Control (2011)

We present a theoretical description of how continuous monomer production affects the focusing of nanocrystal size distributions in solution. We show that sufficiently high monomer production rates can drive a decrease in the polydispersity even as the average nanocrystal size increases. This is in sharp contrast to Ostwald ripening, where polydispersity increases with mean crystal size. We interpret several experimental nanocrystal studies through our model and show how production-controlled growth promises exquisite control over the size and polydispersity of functional nanocrystals.
Preliminary study on a 3D field permanent magnet flux switching machine - from tubular to rotary configurations (2012)

A permanent magnet flux switching (PMFS) machine has a simple rotor, whilst both magnets and coils are set in the stator, resulting in easy removal of heat due to both copper loss and eddy current loss in magnets. However, the volume of magnets used in PMFS machines is usually larger than in conventional PM machines, and leakage flux does exist at the non-airgap side. To make full use of the magnets and gain higher power density, a novel 3-dimensional (3D) field PMFS machine is developed. It combines merits of the tubular linear machine, external-rotor rotary machine and axial-flux rotary machine, hence, offers high power density and peak torque capability, as well as efficient utility of magnets owing to the unique configuration of triple airgap fields.
Incidence of Factor VIII Inhibitor Development in Hemophilia A Patients Treated with Less Pure Plasma Derived Concentrates (1994)

Very-high-purity Factor VIII concentrates produced by monoclonal or recombinant technology have been postulated to be more antigenic resulting in an increased risk of inhibitor development in hemophilia A patients. However, previous reports, mainly based on prevalence figures, may have underestimated the "true" risk of this complication in patients treated with less pure Factor VIII concentrates. The present study, started in 1975, has been designed to calculate the risk of inhibitor development in patients with severe or moderate hemophilia A, followed since their first exposure to intermediate or high-purity Factor VIII concentrates, produced by conventional technologies. Sixty-four hemophiliacs fulfilled the enrollment criteria. Inhibitors developed in 20.3% (13/64) of all patients and in 23% (11/48) of those with severe Factor VIII deficiency. Eleven patients manifested a strong anamnestic response after exposure to Factor VIII (high responders) and 2 had low inhibitor concentrations despite repeated Factor VIII infusions (low responders). The incidence of inhibitor development was 24.6 per 1000 patient-years of observation. The cumulative risk of inhibitor formation was 19.9% at age of 6 years, and 20.3% at 5 years after the first exposure. The risk was 19.3% at 70 days of exposure to Factor VIII concentrates, and 17.2% after a total of 50,000 units of Factor VIII given. Further studies are needed to confirm the above risk of acquiring an inhibitor, which indicates an under-estimation by previous studies. In addition, more data is needed to demonstrate whether very-high-purity Factor VIII concentrates may be more antigenic than conventional preparations.
Capsaicin cream 0.025% as Monotherapy for Osteoarthritis: A double-blind study (1994)

The efficacy and safety of 0.025% capsaicin cream were evaluated when it was used as the only symptomatic therapy in patients with osteoarthritis (OA) pain. Patients (113) received either topical capsaicin or vehicle four times daily in this 12-week, double-blind, randomized, vehicle-controlled, multicenter study. Capsaicin was superior to vehicle in providing pain relief. At the end of the study, more patients on capsaicin (81 %) than vehicle (54%) were improved by physician's global evaluation (P = .03). Similar results were obtained by patient's global evaluation. Capsaicin-treated patients reported greater reduction of pain on the visual analog scale (VAS) at week 4 (P = .01), week 8 (P = .01), and week 12 (P = .02). Capsaicin -treated patients also had greater reduction in pain on passive range of motion by week 8 (P = .03) that was sustained through week 12 (P = .03). Joint tenderness evaluated by palpation declined in capsaicin-treated patients at week 4 (P = .03), week 8 (P = .01 ), and week 12 (P = .01 ). Adverse effects attributable to capsaicin were mild to moderate burning and stinging at the application site (46% of patients). The burning resolved in most patients; only 3 (7%) patients experienced burning at week 12. These results support the beneficial effects of 0.025% capsaicin cream as a first-line therapy for OA pain.
EphB6-null mutation results in compromised T cell function (2004)

So far, there is very limited knowledge about the role of Eph kinases, the largest family of receptor tyrosine kinases, in the immune system. Here, using EphB6 -/-mice, we demonstrated that in vitro and in vivo T cell responses such as lymphokine secretion, proliferation, and the development of delayed-type skin hypersensitivity and experimental autoimmune encephalitis in EphB6 -/-mice were compromised. On the other hand, humoral immune responses, such as serum levels of different Ig isotypes and IgG response to tetanus toxoid, were normal in these mice. Mechanistically, we showed that EphB6 migrated to the aggregated TCRs and rafts after TCR activation. Further downstream, in the absence of EphB6, ZAP-70 activation, LAT phosphorylation, the association of PLC1 with SLP-76, and p44/42 MAPK activation were diminished. Thus, we have shown that EphB6 is pivotal in T cell function.
Power Loss Analysis and Comparison of Segmented and Unsegmented Energy Coupling Coils for Wireless Energy Transfer (2014)

This paper investigated the power losses of unsegmented and segmented energy coupling coils for wireless energy transfer. Four 30-cm energy coupling coils with different winding separations, conductor cross-sectional areas, and number of turns were developed. The four coils were tested in both unsegmented and segmented configurations. The winding conduction and intrawinding dielectric losses of the coils were evaluated individually based on a well-established lumped circuit model. We found that the intrawinding dielectric loss can be as much as seven times higher than the winding conduction loss at 6.78 MHz when the unsegmented coil is tightly wound. The dielectric loss of an unsegmented coil can be reduced by increasing the winding separation or reducing the number of turns, but the power transfer capability is reduced because of the reduced magnetomotive force. Coil segmentation using resonant capacitors has recently been proposed to significantly reduce the operating voltage of a coil to a safe level in wireless energy transfer for medical implants. Here, we found that it can naturally eliminate the dielectric loss. The coil segmentation method and the power loss analysis used in this paper could be applied to the transmitting, receiving, and resonant coils in two- and four-coil energy transfer systems.
DIÁLOGO DE SABERES NA RELAÇÃO JUVENTUDE-ESCOLA-COMUNIDADE: UM ENCONTRO DE GERAÇÕES COM A POÉTICA NARRATIVA DA MEMÓRIA (2021)

The objective of this study was to understand and highlight the educational potentialities, related to the dialogue between scientific and non-scientific knowledge, of an extension project that promotes the dialogue between scientific and non-scientific knowledge, of an outreach project that promotes artistic-pedagogical artistic-pedagogical actions through the dialogue between generations, having visual art, collective memory and the ecology of knowledge perspective as mediators. memory and the perspective of the ecology of knowledge as mediators. This work is based is based on the foundations of Boaventura Santos (2007, 2010), in relation to his perspective on the "Ecology of knowledge" and the "Ecology of knowledge", and Paulo Freire's (1996, 2011a, 2011b). The relationship between poetic narratives and collective memory was based on the studies of. Halbwachs (2004) and Walter Benjamin (1984, 1994, 1995). This research was organized on the basis of an exploratory qualitative exploratory study, adopting the case study as a research technique. research technique. The locus of the research was defined as the rural space, and young high school students and a family were investigated. high school students and a family of family farmers were investigated. The results of this The results of this research indicate that the participating students, when involved in dialogues with peasant subjects, mobilized different different knowledge linked to the construction of collective and dialogic processes that allow for the collective and dialogic processes that allow relating different forms of school or non-school knowledge. It was also found that the discourses and practices of the students manifested reflections on the ecology of knowledge perspective with the intention of applying it in artistic-pedagogical actions that occurred during the execution of the extension project investigated.
Structural Analysis and Construction of an Arch Bridge in Albenga, Italy (2001)

The reconstruction of a damaged steel bridge in the town of Albenga was necessary as a consequence of flooding in November 1994. Constraints due to the dimensions and of an historic/environmental nature demanded an unusual design and the realisation of a tied-arch bridge spanning almost 100 m. The aim of reuniting the divided town as soon as possible was achieved in 10 months with a steel structure. This paper deals with the criteria that determined the choice of structural design, the static and dynamic analyses performed, the main stages of construction, and the testing of the bridge.
Recent applications of conductivity detection in capillary and chip electrophoresis (2006)

The review provides a comprehensive survey of the recent applications of contact and contactless conductivity detection in capillary electrophoretic and chip electrophoretic analyses of a broad scale of compounds, from low-molecular-mass highly mobile small inorganic and organic ions, via medium-molecular-mass peptides and oligo- and polynucleotides up to high-molecular-mass biopolymers, proteins and nucleic acids fragments. The review presents also the recent developments in the construction of different types of conductivity detectors (detectors with galvanic contact of the sensing electrodes with the BGE and sample components, contactless conductivity detectors with capacitively coupled tubular and semitubular electrodes and combined conductivity/optical detectors) applied in the capillary electromigration methods performed in classical fused silica, polytetrafluorethylene, and polyetheretherketone capillaries or on glass and polymethylmethacrylate microchips. In addition, the principle and theoretical bases of conductivity detection in capillary electromigration techniques, zone electrophoresis, ITP, micellar EKC, and electrochromatography are briefly described.
The Salford Psoriasis Index: an holistic measure of psoriasis severity (2000)

We have developed, tested and validated a new scoring system for psoriasis: the Salford Psoriasis Index (SPI). The SPI incorporates the current clinical extent of psoriasis based on the Psoriasis Area and Severity Index (PASI), a score indicating psychosocial disability, and past severity based on treatment history. The resultant three-figure SPI (signs, psychosocial disability, interventions) is a similar paradigm to the TNM (tumour, nodes, metastasis) classification used for cancer staging. The first figure transforms the PASI into a number from 0 to 10 reflecting extent of psoriasis. The second assesses the psychosocial impact of psoriasis on each patient using a 0-10 visual analogue scale. The third figure reflects historical severity of disease as judged by the need for systemic treatment, admission to hospital and number of episodes of erythroderma. The SPI was prospectively employed in assessing 150 consecutive patients with psoriasis. Furthermore, in a separate cohort of 100 patients we tested the Psychosocial Impact Score against a recognized self-report psoriasis-specific measure, the Psoriasis Disability Index. There was a strong correlation between the two (r = 0.59, P < 0.001). However, the Psychosocial Impact Score correlated poorly with clinical extent scores such as the PASI (r = 0.28, P < 0.05) and the Self-administered PASI in 72 patients tested (r = 0.19, P = 0.1). There was a high correlation between all six observers in 20 patients for both PASI (r = 0.71; 95% confidence interval, CI 0.51-0.86) and the Extent Score (r = 0.70; 95% CI 0. 56-0.89). We believe that the SPI will be more relevant to real-life categorization of psoriasis severity in that it takes an holistic approach based not only on physician assessment but also psychological disability and treatment resistance.
A 1.6-kW, 110-kHz DC-DC converter optimized for IGBT's (1993)

A full bridge DC-DC power converter using a zero current and zero-voltage switching technique is described. This circuit utilizes the characteristics of the IGBT to achieve power and frequency combinations that are much higher than previously reported for this device. Experimental results are included for a 1.6 kW, 110 kHz converter with 95% efficiency.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>