gebhart/patrepeval huggingface dataset:
A constant-factor approximation algorithm for packet routing, and balancing local vs. global criteria (1997)

Article Free Access Share on A constant-factor approximation algorithm for packet routing, and balancing local vs. global criteria Authors: Aravind Srinivasan Dept. of Information Systems & Computer Science, National University of Singapore, Singapore 119260, Republic of Singapore Dept. of Information Systems & Computer Science, National University of Singapore, Singapore 119260, Republic of SingaporeView Profile , Chung-Piaw Teo Department of Decision Sciences, National University of Singapore, Singapore 119260, Republic of Singapore Department of Decision Sciences, National University of Singapore, Singapore 119260, Republic of SingaporeView Profile Authors Info & Claims STOC '97: Proceedings of the twenty-ninth annual ACM symposium on Theory of computingMay 1997 Pages 636–643https://doi.org/10.1145/258533.258658Published:04 May 1997Publication History 29citation342DownloadsMetricsTotal Citations29Total Downloads342Last 12 Months31Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
The 140-kilodalton antiangiogenic fragment of thrombospondin-1 binds to basic fibroblast growth factor. (1997)

Thrombospondin-1 (TSP) inhibits the angiogenic activity of basic fibroblast growth factor (bFGF). Here we address the hypothesis of a direct interaction between TSP and bFGF. Gel permeation chromatography and cross-linking experiments demonstrated that bFGF binds to TSP in solution. bFGF also bound to immobilized TSP in a solid-phase assay. Binding was dose-dependent, with a Kd in the nanomolar range, and was inhibited by anti-TSP antibodies. The 140-kDa carboxyl-terminal fragment of TSP, but not the 25-kDa heparin-binding fragment, fully retained the bFGF binding capacity. Accordingly, binding was inhibited by monoclonal antibodies directed against this fragment. Heparin completely blocked bFGF binding to TSP and to the 140-kDa fragment. TSP and its 140-kDa fragment inhibited the binding of bFGF to endothelial cells at concentrations (> or = 100 nM) that inhibited endothelial cell proliferation but not motility. Low-affinity binding was inhibited more than high-affinity binding (up to 76 and 41% inhibition, respectively), and the inhibition was reversed by anti-TSP antibodies. Vitronectin and transforming growth factor beta, potentially associated with TSP, did not affect bFGF binding to endothelial cells. Although TSP did not affect the activation of the high-affinity receptors, it reduced the long-term internalization of bFGF. We conclude that TSP binds to bFGF through a domain within its 140-kDa fragment, a mechanism that might affect bFGF interaction with endothelial cells, activity, and association with the extracellular matrix.
Properties of New Transition Metal Chalcogenides and Pnictides. (1979)

Abstract : This report presents the results of studies of new transition metal magnetic compounds and includes (1) high pressure phase transformation studies of Pd(1-x)M(x)Se(2) (M=Ru, Co, Ni) and of M(1-x)Rh(x)Se(2) (M=Pd, Pt), (2) preparation and properties of indium antimony selenides, and (3) crystal growth and characterization of the transition metal phosphides CuP2, NiP2, and RhP3. (Author)
Preface to the second edition (2007)

This edition of A Practical Introduction has two major differences from the previous one. The first is a discussion of quantum chemical and hybrid potential methods for calculating the potential energies of molecular systems. Quantum chemical approaches are more costly than molecular mechanical techniques but are, in principle, more ‘exact’ and greatly extend the types of phenomena that can be studied with the other algorithms described in the book. The second difference is the replacement of fortran 90 by Python as the language in which the dynamo module library and the book's computer programs are written. This change was aimed to make the library more accessible and easier to use. As well as these major changes, there have been many minor modifications, some of which I wanted to make myself but many that were inspired by the suggestions of readers of the first edition.
Formation and Properties of Reactive Aldehydes (1979)

4-Hydroxyalkenals react easily with SH groups in enzymes and structural proteins to give stable adducts in which the aldehyde is bound through a thioether linkage to the protein. This reaction represents the mechanism by which these compounds block certain metabolic processes (DNA, RNA and protein synthesis, respiration, glycolysis) and exert their antitumour activity. A highly significant inverse correlation exists between the number of hydroxypentenal-sensitive SH groups in the soluble proteins and the doubling time of 12 transplantable animal tumours. Hydroxyalkenals applied peritumourally completely prevent or significantly delay growth of the solid forms of four animal tumours. The almost non-toxic adducts of 4-hydroxypentenal-cysteine 1:1 and crotonal-cysteine 1:2 applied intraperitoneally prevent or inhibit growth of Ehrlich ascites tumour in mice. The possible formation of unsaturated aldehydes in vivo from lipids, carbohydrates and diamines is discussed.
Influence of the Dialysis Membrane on Markers of Tissue Ischemia (2006)

We concluded that ADO is a more sensitive marker of ischemia than IMA and that, under our HD conditions, the ischemia caused by HD was very weak, independent of the dialysis membrane.
ChemInform Abstract: Synthetic Studies on Natural Products. Part 13. Clay Catalyzed Convenient Isomerization of Natural Furofuran Lignans under Microwave Irradiation. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
REVIEW OF THE BIOSTIMULATION SESSION OF THE 11th MEETING OF THE AMERICAN SOCIETY FOR LASER MEDICINE AND SURGERY (ASLMS) (1991)

San Diego was once again the site for the 11th meeting of the American Society for Laser Medicine and Surgery (ASLMS), the 10th anniversary meeting of this association. It was held in the Sheraton Harbor Iland, San Diego. California, form April 29th to May 1st 1991. inclusive. The reviewer has been at every one of these except the first meeting in 1911, and it is very interesting to review the programmes over the past 10 meetings That he has attended. Especially as far as the gradual separation of photobioactivation studies and clinical laser therapy papers into their own category of ‘biostimulation’, This year, the Biostimulation Session Programme Chairperson was Dr Juanita J. Anders. , of the Uniformed University of the Health Science, Bethesda. Maryland, Dr Anders has produced a number of excellent studies which by and large show a significant LLLT effect on nerve and related structures compared with controls. Thirteen papers were scheduled for presentation during this session, extended at Dr Anders' request to allow a fuller representation of what is happening in the LLLT world; unfortunately the Russian group (Vestibulo-dependence tachyarrhythmias, and treatment results using HeNe laser: V. Zalessy. I. Michalkin and V. Bobrov) and the Argentinian group (Blockade of inflammatory signals by laser radiation: J. Palma. H. Juri, V. Camapna et al.) were ‘no-shows ’. However this did mean that there was in fact mere time at Dr Anders' disposal to allow for more detailed discussion after the papers, and for an unscheduled free forum at the end of the session.
Reviews of Books (1938)

Reviews of Books Get access The Victoria History of the Counties of England. Rutland. Vol. ii. Edited by the late WILLIAM PAGE. (London: St. Catherine Press, 1935.) Sussex. Vol. iii, 1935; vol. ix, 1937. Northampton. Vol. iv, 1937. Edited by L. F. SALEMAN, published for the University of London, Institute of Historical Research, by the Oxford University Press. H. M. CAM H. M. CAM Search for other works by this author on: Oxford Academic Google Scholar The English Historical Review, Volume LIII, Issue CCXI, July 1938, Pages 521–526, https://doi.org/10.1093/ehr/LIII.CCXI.521 Published: 01 July 1938
Assessment of right ventricle volumes and function by cardiac MRI: Quantification of the regional and global interobserver variability (2011)

Reproducibility of the manual assessment of right ventricle volumes by short-axis cine-MRI remains low and is often attributed to the difficulty in separating the right atrium from the ventricle. This study was designed to evaluate the regional interobserver variability of the right ventricle volume assessment to identify segmentation zones with the highest interobserver variability. Short-axis views of 90 right ventricles (30 hypertrophic, 30 dilated, and 30 normal) were acquired with 2D steady-state free precession sequences at 1.5 T and were manually segmented by two observers. The two segmentations were compared and the variations were quantified with a variation score based on the Hausdorff distance between the two segmentations and the interobserver 95% limits of concordance of the global volumes. The right ventricles were semiautomatically split into four subregions: apex, mid-ventricle, tricuspid zone, and infundibulum. These four subregions represented 11%, 34%, 36%, and 19% of the volume but, respectively, yielded variation scores of 8%, 16%, 42%, and 34%. The infundibulum yielded the highest interobserver regional variability although its variation score remained comparable to the tricuspid zone due to its lower volume. These results emphasize the importance of standardizing the segmentation of the infundibulum and the tricuspid zone to improve reproducibility.
Towards Determining the Interaction of Fluids with Nanostructured Carbons (2006)

Development of efficient approaches for modeling of nanostructures and nanofluidics is a major goal of theoretical and computational scientists. Here we focus on developing a scheme to accurately and efficiently predict the interactions of fluid molecules with nanostructured carbons where the interactions are weak and relatively short-range. As a model of these systems we consider the interaction of neon with simple polyaromatic hydrocarbons, and demonstrate that the use of basis sets of high local quality can provide a very useful approach
A Forest Fire Detection System Based on Ensemble Learning (2021)

Due to the various shapes, textures, and colors of fires, forest fire detection is a challenging task. The traditional image processing method relies heavily on manmade features, which is not universally applicable to all forest scenarios. In order to solve this problem, the deep learning technology is applied to learn and extract features of forest fires adaptively. However, the limited learning and perception ability of individual learners is not sufficient to make them perform well in complex tasks. Furthermore, learners tend to focus too much on local information, namely ground truth, but ignore global information, which may lead to false positives. In this paper, a novel ensemble learning method is proposed to detect forest fires in different scenarios. Firstly, two individual learners Yolov5 and EfficientDet are integrated to accomplish fire detection process. Secondly, another individual learner EfficientNet is responsible for learning global information to avoid false positives. Finally, detection results are made based on the decisions of three learners. Experiments on our dataset show that the proposed method improves detection performance by 2.5% to 10.9%, and decreases false positives by 51.3%, without any extra latency.
Upper Cervical Chiropractic Management of a Multiple Sclerosis Patient: A Case Report (2001)

This article reviews the upper cervical chiropractic management of a single patient with Multiple Sclerosis (MS).This 47-year-old female first experienced symptoms of MS at age 44, when she noticed cognitive problems and loss of bladder control. After viewing multiple lesions on MRI (MS plaques), her neurologist diag- nosed her with MS. Two years later, she noticed additional symptoms of leg weakness and paresthesias in her arms and legs. Her symptoms progressively worsened without remission, so her neurologist categorized her as having chronic progressive MS and recommended drug therapy (Avonex). Upon initial examination of this patient, evi- dence of an upper cervical subluxation was found using precise upper cervical radiographs and paraspinal digital infrared imaging. The patient's medical history included one possible mechanism (a fall approximately ten years prior), which could have caused her upper cervical subluxation. The patient was placed on a specially designed knee-chest table for adjustment, which was delivered by hand to the first cervical vertebra according to radiographic findings. Monitoring of the patient's progress was through doctor's observation, patient's subjective description of symptoms, thermographic scans, neurologist's evaluation and MRI. The patient was managed with upper cervical chiropractic care for two years.After four months of upper cervical chiropractic care, all MS symptoms were absent. A follow-up MRI showed no new lesions as well as a reduction in intensity of the original lesions. After a year passed in which the patient remained asymptomatic, another follow-up MRI was performed. Once again, the MRI showed no new lesions and a continued reduction in intensity of the original lesions. Two years after upper cervi- cal chiropractic care began, all MS symptoms remained absent.This case report revealed that this specific upper cer- vical procedure (thermal imaging, cervical radiographs, and knee-chest adjustments) was associated with a success- ful outcome for a patient with Multiple Sclerosis. Post MRI's, post thermographic scans, and the patient's neurol- ogist's evaluation all suggested the intervention of upper cervical chiropractic care may have stimulated a reversal in the progression of Multiple Sclerosis.
Optimal Algorithms for Universal Random Number Generation From Finite Memory Sources (2014)

We study random number generators (RNGs), both in the fixed to variable-length (FVR) and the variable to fixed-length (VFR) regimes, in a universal setting in which the input is a finite memory source of arbitrary order and unknown parameters, with arbitrary input and output (finite) alphabet sizes. Applying the method of types, we characterize essentially unique optimal universal RNGs that maximize the expected output (respectively, minimize the expected input) length in the FVR (respectively, VFR) case. For the FVR case, the RNG studied is a generalization of Elias's scheme, while in the VFR case the general scheme is new. We precisely characterize, up to an additive constant, the corresponding expected lengths, which include second-order terms similar to those encountered in universal data compression and universal simulation. Furthermore, in the FVR case, we consider also a twice-universal setting, in which the Markov order k of the input source is also unknown.
Characterization of the Interaction of β-Amyloid with Transthyretin Monomers and Tetramers (2010)

β-Amyloid (Aβ) is the main protein component of the amyloid plaques associated with Alzheimer's disease. Transthyretin (TTR) is a homotetramer that circulates in both blood and cerebrospinal fluid. Wild-type (wt) TTR amyloid deposits are linked to senile systemic amyloidosis, a common disease of aging, while several TTR mutants are linked to familial amyloid polyneuropathy. Several recent studies provide support for the hypothesis that these two amyloidogenic proteins interact, and that this interaction is biologically relevant. For example, upregulation of TTR expression in Tg2576 mice was linked to protection from the toxic effects of Aβ deposition [Stein, T. D., and Johnson, J. A. (2002) J. Neurosci. 22, 7380-7388]. We examined the interaction of Aβ with wt TTR as well as two mutants: F87M/L110M, engineered to be a stable monomer, and T119M, a naturally occurring mutant with a tetrameric stability higher than that of the wild type. On the basis of enzyme-linked immunoassays as well as cross-linking experiments, we conclude that Aβ monomers bind more to TTR monomers than to TTR tetramers. The data further suggest that TTR tetramers interact preferably with Aβ aggregates rather than Aβ monomers. Through tandem mass spectrometry analysis of cross-linked TTR-Aβ fragments, we identified the A strand, in the inner β-sheet of TTR, as well as the EF helix, as regions of TTR that are involved with Aβ association. Light scattering and electron microscopy studies demonstrate that the outcome of the TTR-Aβ interaction strongly depends on TTR quaternary structure. While TTR tetramers may modestly enhance aggregation, TTR monomers decidedly arrest Aβ aggregate growth. These data provide important new insights into the nature of TTR-Aβ interactions. Such interactions may regulate TTR-mediated protection against Aβ toxicity.
Lower‐dimensional interface elements with local enrichment: application to coupled hydro‐mechanical problems in discretely fractured porous media (2012)

SUMMARY In this study, we develop lower‐dimensional interface elements to represent preexisting fractures in rock material, focusing on finite element analysis of coupled hydro‐mechanical problems in discrete fractures–porous media systems. The method adopts local enrichment approximations for a discontinuous displacement and a fracture relative displacement function. Multiple and intersected fractures can be treated with the new scheme. Moreover, the method requires less mesh dependencies for accurate finiteelement approximations compared with the conventional interface element method. In particular, for coupled problems, the method allows for the use of a single mesh for both mechanical and other related processes such as flow and transport. For verification purposes, several numerical examples are examined in detail. Application to a coupled hydro‐mechanical problem is demonstrated with fluid injection into a single fracture. The numerical examples prove that the proposed method produces results in strong agreement with reference solutions. Copyright © 2012 John Wiley & Sons, Ltd.
MUSE: An Efficient and Accurate Verifiable Privacy-Preserving Multikeyword Text Search over Encrypted Cloud Data (2017)

With the development of cloud computing, services outsourcing in clouds has become a popular business model. However, due to the fact that data storage and computing are completely outsourced to the cloud service provider, sensitive data of data owners is exposed, which could bring serious privacy disclosure. In addition, some unexpected events, such as software bugs and hardware failure, could cause incomplete or incorrect results returned from clouds. In this paper, we propose an efficient and accurate verifiable privacy-preserving multikeyword text search over encrypted cloud data based on hierarchical agglomerative clustering, which is named MUSE. In order to improve the efficiency of text searching, we proposed a novel index structure, HAC-tree, which is based on a hierarchical agglomerative clustering method and tends to gather the high-relevance documents in clusters. Based on the HAC-tree, a noncandidate pruning depth-first search algorithm is proposed, which can filter the unqualified subtrees and thus accelerate the search process. The secure inner product algorithm is used to encrypted the HAC-tree index and the query vector. Meanwhile, a completeness verification algorithm is given to verify search results. Experiment results demonstrate that the proposed method outperforms the existing works, DMRS and MRSE-HCI, in efficiency and accuracy, respectively.
Politics and United States Foreign Policy (1957)

Journal Article Politics and United States Foreign Policy Get access D. W. Brogan D. W. Brogan Search for other works by this author on: Oxford Academic Google Scholar International Affairs, Volume 33, Issue 2, April 1957, Pages 165–175, https://doi.org/10.2307/2608853 Published: 01 April 1957
<i>Corynebacterium diphtheriae</i> : Identification and Characterization of a Channel-Forming Protein in the Cell Wall (2007)

The cell wall fraction of the gram-positive, nontoxic Corynebacterium diphtheriae strain C8r(-) Tox- (=ATCC 11913) contained a channel-forming protein, as judged from reconstitution experiments with artificial lipid bilayer experiments. The channel-forming protein was present in detergent-treated cell walls and in extracts of whole cells obtained using organic solvents. The protein had an apparent molecular mass of about 66 kDa as determined on Tricine-containing sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels and consisted of subunits having a molecular mass of about 5 kDa. Single-channel experiments with the purified protein suggested that the protein formed channels with a single-channel conductance of 2.25 nS in 1 M KCl. Further single-channel analysis suggested that the cell wall channel is wide and water filled because it has only slight selectivity for cations over anions and its conductance followed the mobility sequence of cations and anions in the aqueous phase. Antibodies raised against PorA, the subunit of the cell wall channel of Corynebacterium glutamicum, detected both monomers and oligomers of the isolated protein, suggesting that there are highly conserved epitopes in the cell wall channels of C. diphtheriae and PorA. Localization of the protein on the cell surface was confirmed by an enzyme-linked immunosorbent assay. The prospective homology of PorA with the cell wall channel of C. diphtheriae was used to identify the cell wall channel gene, cdporA, in the known genome of C. diphtheriae. The gene and its flanking regions were cloned and sequenced. CdporA is a protein that is 43 amino acids long and does not have a leader sequence. cdporA was expressed in a C. glutamicum strain that lacked the major outer membrane channels PorA and PorH. Organic solvent extracts of the transformed cells formed in lipid bilayer membranes the same channels as the purified CdporA protein of C. diphtheriae formed, suggesting that the expressed protein is able to complement the PorA and PorH deficiency of the C. glutamicum strain. The study is the first report of a cell wall channel in a pathogenic Corynebacterium strain.
The potential of human mast cell progenitors to differentiate into mature mast cells remains after prolonged culture with flt3 ligand, interleukin‐3 or granulocyte‐macrophage colony stimulating factor (1999)

Stem cell factor (SCF) plays a key role in the development of mast cells from haemopoietic progenitor cells. In this study we have investigated the effect of the early acting haemopoietic cytokines flt3 ligand (FL), IL-3 and GM-CSF on the SCF-dependent differentiation of mast cells from cord blood mononuclear cells. By using delayed addition of SCF, we examined the potential of mast cell progenitors to keep their capacity to differentiate into mast cells after exposure to factors signalling differentiation into other lineages. Culture with either cytokine for 3 weeks before transfer to SCF-containing medium resulted in the development of mast cells in all cultures. The appearance of mast cells was attenuated when the cells had been in culture with IL-3 or GM-CSF prior to culture in SCF, compared to cultures exposed to SCF alone for 7 weeks. However, a proportion of the cells had not lost the capacity to develop into mast cells. In contrast, in cultures initiated with FL and transferred to medium containing SCF, the same amount of mast cells developed as in the SCF cultures. Thus, cells committed to the mast cell lineage appear to be resistant to the lineage directives of IL-3 and GM-CSF and keep their potential to differentiate into mature mast cells.