gebhart/patrepeval huggingface dataset:
Design of an Efficient Quantum Circuit Simulator (2010)

Work is in progress throughout the globe to efficiently use the potential of the quantum theory of computation over their classical counterpart and hence there is a need of building quantum computing hardware. The target of building quantum computers can be achieved if we have better tools for the design of quantum hardware. Quantum circuit simulators are tools for the logic verification of quantum circuits and they can be an essential component of quantum CAD tools in the future. This work is the extension of the previous work by the authors, in order to increase the efficiency of the simulator and to incorporate more components in the gate library. In this paper we have proposed an efficient simulator which can simulate a quantum circuit specified using the proposed quantum hardware descriptive language (QHDL).
Performance of Joint Spectrum Sensing and MAC Algorithms for Multichannel Opportunistic Spectrum Access Ad Hoc Networks (2010)

We present an analytical framework to assess the link layer throughput of multichannel Opportunistic Spectrum Access (OSA) ad hoc networks. Specifically, we focus on analyzing various combinations of collaborative spectrum sensing and Medium Access Control (MAC) protocol abstractions. We decompose collaborative spectrum sensing into layers, parametrize each layer, classify existing solutions, and propose a new protocol called Truncated Time Division Multiple Access (TTDMA) that supports efficient distribution of sensing results in "k out of N" fusion rule. In case of multichannel MAC protocols we evaluate two main approaches of control channel design with (i) dedicated and (ii) hopping channel. We propose to augment these protocols with options of handling secondary user (SU) connections preempted by primary user (PU) by (i) connection buffering until PU departure and (ii) connection switching to a vacant PU channel. By comparing and optimizing different design combinations we show that (i) it is generally better to buffer preempted SU connections than to switch them to PU vacant channels and (ii) TTDMA is a promising design option for collaborative spectrum sensing process when k does not change over time.
Active array radar systems applied to air traffic control (2002)

Increased traffic flow, mobility, safety, and decreasing T/R module costs, will lead the way for future air traffic control (ATC) radar systems to be based on GaAs active array radar (AAR) technology. In this paper, system tradeoffs and potential architectures are described for civil ATC radars and mobile military ATC radars. Current developments are provided in transmit-receive (T/R) module state of the art, the enabling technology. Discussions include the potential for large AARs with single or multiple arrays located at airport terminals to simultaneously undertake functions presently performed by the airport surveillance radar (ASR), the precision approach radar (PAR), the terminal Doppler weather radar (TDWR), and the airport surface detection equipment (ASDE) radars for increased performance at lower cost. These features are accomplished through the beam agility, wide bandwidth, multimode adaptive waveforms and power programming features only possible with the AAR.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Ginseng-derived nanoparticles alter macrophage polarization to inhibit melanoma growth (2019)

GDNPs can alter M2 polarization both in vitro and in vivo, which contributes to an antitumor response. The polarization of macrophages induced by GDNPs is largely dependent on TLR4 and MyD88 signalling. GDNPs as an immunomodulator participate in mammalian immune response and may represent a new class of nano-drugs in cancer immunotherapy.
The Insulin-like Growth Factors (1992)

Journal Article The Insulin-like Growth Factors Get access JD QUIN JD QUIN From the Diabetic Unit, Stirling Royal InfirmaryLivilands, Stirling FK8 2A U Search for other works by this author on: Oxford Academic PubMed Google Scholar QJM: An International Journal of Medicine, Volume 82, Issue 2, February 1992, Pages 81–90, https://doi.org/10.1093/oxfordjournals.qjmed.a068658 Published: 01 February 1992 Article history Accepted: 09 October 1991 Published: 01 February 1992
Joint disparity and optical flow by correspondence growing (2011)

The scene flow in binocular stereo setup is estimated using a seed growing algorithm. A pair of calibrated and synchronized cameras observe a scene and output a sequence of images. The algorithm jointly computes a disparity map between the stereo images and optical flow maps between consecutive frames. Having the calibration, this is a representation of the scene flow, i.e. a 3D velocity vector is associated with each reconstructed 3D point. The proposed algorithm starts from correspondence seeds and propagates the correspondences to the neighborhood. It is accurate for complex scenes with large motion and produces temporally coherent stereo disparity and optical flow results. The algorithm is fast due to inherent search space reduction.
Design, Synthesis and Biological Evaluation of Novel Etoposide Analogues as Cytotoxic Agents (2006)

Abstract Five novel compounds composed of etoposide and 5‐fluorouracil derivatives joined by an ester linkage were prepared and evaluated for their antitumor potential. Most of these analogues have exhibited promising in vitro cytotoxic activity against cell cultures of murine leukaemia P‐388 and human lung carcinoma A‐549. The results presented herein challenged the long‐standing structure‐activity relationships, which proposed that a free 4′‐hydroxyl group is essential structural requirement for etoposide‐like activity. And in addition, the 4′‐position was suggested to tolerate chemical modifications such as esterification. The preliminary testing results also indicated that the design and synthesis of these compounds were beneficial for therapeutic values of etoposide.
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration (2012)

Pluripotent cells represent a powerful tool for tissue regeneration, but their clinical utility is limited by their propensity to form teratomas. Little is known about their interaction with the surrounding niche following implantation and how this may be applied to promote survival and functional engraftment. In this study, we evaluated the ability of an osteogenic microniche consisting of a hydroxyapatite-coated, bone morphogenetic protein-2-releasing poly-L-lactic acid scaffold placed within the context of a macroenvironmental skeletal defect to guide in vivo differentiation of both embryonic and induced pluripotent stem cells. In this setting, we found de novo bone formation and participation by implanted cells in skeletal regeneration without the formation of a teratoma. This finding suggests that local cues from both the implanted scaffold/cell micro- and surrounding macroniche may act in concert to promote cellular survival and the in vivo acquisition of a terminal cell fate, thereby allowing for functional engraftment of pluripotent cells into regenerating tissue.
Process analysis and abnormal situation detection: from theory to practice (2002)

The article discusses the use of latent variable models based on historical data and examines their potential and limitations for improving operations for both batch and continuous processes. The use of these models for multivariate statistical process monitoring, abnormal situation detection, and fault diagnosis is demonstrated. Examples from state-of-the-art major industrial applications currently running online illustrate the tremendous potential of these methods. In this context, an industrial application for abnormal situation detection is defined as "state of the art" if it has been operational several years after it was commissioned, has generated large savings, has been operating safely and/or has improved safety conditions in the plant, and is accepted enthusiastically by the operators. Such an application could be based entirely on known theory, but frequently it includes company proprietary modifications to suit the particular operating characteristics of the process. The article contains an extensive literature review on the subject and practical considerations for the user, as well as warnings about potential pitfalls in areas ranging from data acquisition to modeling to online application.
Protecting Children in Nontraditional Families: Second Parent Adoptions in Washington (1990)

Most adults take for granted their right, through marriage and adoption, to legally protect their relationship with children. A substantial segment of adults, however, cannot take this right for granted. In some states these individuals are denied the right to have a legal relationship with their partners' children because they are lesbians. The rights and needs of children in these nontraditional families could be recognized through second parent adoptions. In essence, a second parent adoption is the adoption of a child by the partner of the child's natural or legal parent. For example, suppose a lesbian couple, Emily and Lynn, decide to have a child. Emily conceives the child through artificial insemination. Lynn, the nonbirth parent, then petitions the court to adopt Emily's child and the court grants this adoption without terminating Emily's parental rights. The child then has two legal parents through the second parent adoption process.
1,2,4-Triazines. IV. Synthesis and characterization of 1,2,4-triazine N-oxides (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,2,4-Triazines. IV. Synthesis and characterization of 1,2,4-triazine N-oxidesWilliam W. Paudler and Teh-Kuei ChenCite this: J. Org. Chem. 1971, 36, 6, 787–790Publication Date (Print):March 1, 1971Publication History Published online1 May 2002Published inissue 1 March 1971https://pubs.acs.org/doi/10.1021/jo00805a011https://doi.org/10.1021/jo00805a011research-articleACS PublicationsRequest reuse permissionsArticle Views178Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Control of enzyme synthesis in the arginine deiminase pathway of Streptococcus faecalis (1982)

The formation of the arginine deiminase pathway enzymes in Streptococcus faecalis ATCC 11700 was investigated. The addition of arginine to growing cells resulted in the coinduction of arginine diminase (EC 3.5.3.6), ornithine carbamoyltransferase (EC 2.1.3.3), and carbamate kinase (EC 2.7.2.3). Growth on glucose-arginine or on glucose-fumarate-arginine produced a decrease in the specific activity of the arginine fermentation system. Aeration had a weak repressing effect on the arginine deiminase pathway enzymes in cells growing on arginine as the only added substrate. By contrast, depending on the growth phase, a marked repression of the pathway by oxygen was observed in cells growing on glucose-arginine. We hypothesize that, in S. faecalis, the ATP pool is an important signal in the regulation of the arginine deiminase pathway. Mutants unable to utilize arginine as an energy source, isolated from the wild type, exhibited four distinct phenotypes. In group I the three enzymes of the arginine deiminase pathway were present and probably affected in the arginine uptake system. Group II mutants had no detectable arginine deiminase, whereas group III mutants had low levels of ornithine carbamoyltransferase. Group IV mutants were defective for all three enzymes of the pathway.
Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections (2018)

Although the outcome of flavivirus infection can vary from asymptomatic to lethal, environmental factors modulating disease severity are poorly defined. Here, we observed increased susceptibility of mice to severe West Nile (WNV), Dengue, and Zika virus infections after treatment with oral antibiotics (Abx) that depleted the gut microbiota. Abx treatment impaired the development of optimal T cell responses, with decreased levels of WNV-specific CD8<sup>+</sup> T cells associated with increased infection and immunopathology. Abx treatments that resulted in enhanced WNV susceptibility generated changes in the overall structure of the gut bacterial community and in the abundance of specific bacterial taxa. As little as 3 days of treatment with ampicillin was sufficient to alter host immunity and WNV outcome. Our results identify oral Abx therapy as a potential environmental determinant of systemic viral disease, and they raise the possibility that perturbation of the gut microbiota may have deleterious consequences for subsequent flavivirus infections.
A 9-mm<sup>2</sup> Ultra-Low-Power Highly Integrated 28-nm CMOS SoC for Internet of Things (2018)

This paper gives an overview of the Blackghost 1.0 system-on-chip (SoC) from Qualcomm Research, which was our first test chip that paved the way toward the commercialization of Qualcomm’s most recent ultra-low-power Blackghost SoC family. Specifically designed for battery powered Internet of Things, sensor fusion, wearables, and e-medical applications, this highly integrated SoC delivers high-power efficiency through low-power innovations in architecture and circuit domains. It integrates a small footprint sensor control processor based on ARM Cortex-M0, a vision classifier processor, a streaming DSP hardware accelerator, an ultra-low-power analog-front-end, and an on-die power management unit with direct Li-Ion battery attach capability. The die size of this prototype chip is <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$3\times 3$ </tex-math></inline-formula> mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in a 28LP CMOS process technology. To date, this SoC family has successfully progressed to the mass production of near-threshold computing. The logic computation operates at near-threshold voltages (<0.6 V) at frequencies up to 50 MHz and draws less than <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$9~\mu $ </tex-math></inline-formula> A/MHz from the directly attached battery.
The Determination of Thermal Properties of Engine Combustion Chamber Deposits (2000)

<div class="htmlview paragraph">Thermal conductivity and thermal diffusivity of combustion chamber deposits in an s. i. engine and a diesel engine were determined by measuring thickness, response time to a radiation pulse, time-varying deposit surface temperature and deposit-wall interface temperature. The results show that, for the s. i. engine deposits formed with a stoichiometric mixture of unleaded gasoline, the thermal conductivity is hardly influenced by engine load, speed and equivalence ratio, and that thermal diffusivity depends on equivalence ratio, but hardly depends on engine load and speed. The test result with unleaded gasoline containing lubricating oil indicates that the thermal properties are sensitive to the lubricating oil content and depend considerably on engine load. The thermal properties of diesel deposit are the first data that have been presented. The result show that the thermal conductivity depends on engine load and is larger in general than that of s. i. engine and that the thermal diffusivity has no meaningful dependence on engine load and is larger than that of s. i. engine operated with stoichiometric mixture of unleaded gasoline.</div>
PRINCIPLES AND DEFINITIONS FOR CONTINUOUSLY VARIABLE TRANSMISSIONS, WITH EMPHASIS ON AUTOMOTIVE APPLICATIONS (1980)

This paper examines and compares the five basic principles that can be used in continuously variable transmission (CVT) design: (1) hydrostatic, (2) traction drive (V-belt and rolling contact), (3) overrunning clutch, (4) electric, and (5) multispeed gearbox with slipping clutch. The operating characteristics and features of each are considered. The power-split, inverse power-split, and power recirculation modes of operation are discussed, along with applications where they may be advantageously used. Emphasis is directed toward automotive applications, both for conventional vehicles and those employing energy-storage flywheels.
PHILADELPHIA NEUROLOGICAL SOCIETY (1938)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue Archives of Neurology & Psychiatry HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Facial Plastic Surgery JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the Archives of Neurology & Psychiatry journal
Characteristics and Concordance of Autism Spectrum Disorders Among 277 Twin Pairs (2009)

Our data support greater ASD concordance in MZ vs DZ twins. Overall higher functioning, psychiatric comorbidity, and Asperger syndrome concordance among affected MZ vs DZ twins may also suggest differential heritability for different ASDs. For families in which one MZ twin is diagnosed with ASD, the second twin is unlikely to receive an ASD diagnosis after 12 months. In addition, Internet parent report of ASD status is valid.
Effects of Ta addition in CoNi/Cr double layer film sputtered in low Ar gas pressure (1988)

The effects of tantalum and chromium up to 5 at.%, added to the CoNi magnetic layer, on the magnetic properties and media noise of a CoNi/Cr double-layer magnetic recording medium, have been investigated. The CoNi magnetic layer and Cr underlayer were deposited at argon gas pressures as low as 2 and 0.2 mTorr, respectively, using a facing-targets sputtering apparatus. Addition of Cr to CoNi layers with high remanence squareness shows slight improvement of medium noise. The addition of Ts shows significant noise reduction, to the extent of about 3 dB.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
QT Interval Dispersion and its Clinical Utility (1997)

QT dispersion as a measure of interlead variations of QT interval duration in the surface 12-lead ECG is believed to reflect regional differences in repolarization heterogeneity and thus, may provide an indirect marker of arrhythmogenicity. Methodology for determining QT dispersion and reproducibility of this parameter vary significantly between studies and, together with some other unresolved problems with QT dispersion assessment, often lead to contradictory suggestions about potential clinical utility of this parameter. The results of our own study in 213 survivors of myocardial infarction, together with a comprehensive review of the literature, suggest that most of these inconsistencies reflect incomplete understanding of electrocardiographic correlates of both normal and abnormal ventricular repolarization. The application of more objective techniques, such as spectral analysis or combined assessment of different parameters (e.g., area beneath the T wave and its symmetricity) may add a new dimension to the noninvasive assessment of ventricular repolarization.
Full Issue (28.1, Summer 2018) (2018)

The primary purpose of the JTM is to publish managerial and policy articles that are relevant to academics, policymakers, and practitioners in the transportation, logistics and supply chain fields. Acceptable articles could include conceptual, theoretical, legal, case, and applied research that contributes to better understanding and management of transportation and logistics. Saying that, our policy requires that articles be of interest to both academics and practitioners, and that they specifically address the managerial or policy implications of the subject matter.
Distinct effects of Vibrio cholerae haemagglutinin/protease on the structure and localization of the tight junction-associated proteins occludin and ZO-1 (2000)

Vibrio cholerae produces a little-studied cytotoxin, haemagglutinin/protease (HA/P), in addition to several better-characterized enterotoxins, i.e. cholera toxin (CT), zonula occludens toxin (ZOT) and accessory cholera enterotoxin (Ace). We have found recently that HA/P perturbs the barrier function of Mardin-Darby canine kidney epithelial cell line I (MDCK-I) by affecting the intercellular tight junctions (TJs) and the F-actin cytoskeleton. In the present study we have assessed more specifically how TJs are affected by HA/P by investigating the cellular localization and biochemical integrity of two well-characterized TJ-associated proteins, occludin and ZO-1. Western blot analysis showed that occludin bands of 66-85 kDa were digested by HA/P to two predominant bands of around 50 kDa and 35 kDa, and that this degradation was greatly attenuated when the specific bacterial metalloproteinase inhibitor Zincov was co-administered. Trypsin, on the other hand, did not degrade occludin when it was applied in the same way, suggesting that the degradation of occludin by HA/P is an early and specific event. The other TJ-associated protein ZO-1 was not degraded by HA/P in parallel experiments, suggesting the selectivity of HA/P-associated protein degradation. Moreover, immunofluorescence labelling and confocal microscopy showed that ZO-1, but not occludin, around cell-cell boundaries was rearranged by HA/P treatment. Since ZO-1 is located on the inside of the plasma membrane and is directly associated with occludin, the results indicate that breakdown of occludin may send signals to ZO-1 that affect its organization and the structure of the F-actin cytoskeleton. Our finding that the zinc-containing metalloprotease of V. cholerae specifically degraded occludin suggests that specific degradation of important host proteins by bacterial zinc-containing metalloproteases may be an important mechanism in microbial pathogenesis.