gebhart/patrepeval huggingface dataset:
Synthesis of a First-Row Transition Metal Parent Amido Complex and Carbon Monoxide Insertion into the Amide N−H Bond  [<i>J. Am. Chem. Soc.</i> <b>2003</b>, <i>125</i>, 8984−8985]. (2003)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionSynthesis of a First-Row Transition Metal Parent Amido Complex and Carbon Monoxide Insertion into the Amide N−H Bond [J. Am. Chem. Soc.2003, 125, 8984−8985]. Daniel J. Fox and Robert G. BergmanCite this: J. Am. Chem. Soc. 2003, 125, 38, 11772Publication Date (Web):August 28, 2003Publication History Published online28 August 2003Published inissue 1 September 2003https://pubs.acs.org/doi/10.1021/ja0334513https://doi.org/10.1021/ja0334513correctionACS PublicationsCopyright © 2003 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views685Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (13 KB) Get e-Alertsclose Get e-Alerts
Probing-Based Channel Adaptive Video Streaming for Wireless 3G Network (2006)

We propose a probing-based channel adaptive video streaming method to provide seamless video transmission over the wireless 3G network. In the proposed method, the available bandwidth (AB) of the end-to-end path is estimated by analyzing RTP packets at the streaming client and the network/client buffer status (NCBS) is predicted by examining the RTCP receiver report (RR) and the application defined packet (APP) including the AB information. Using the estimated AB, the NCBS, and the stored multirate bitstream information, the proposed streaming method determines the next transmission bitrate precisely. Experimental results indicate that the proposed method can be effectively used for video streaming.
A Ce<sup>2+</sup> sensor based on napthalen-1-yl-methylene-benzenesulfonohydrazide (NMBSH) molecules: ecological sample analysis (2018)

A sensitive and selective Ce<sup>2+</sup> sensor was developed based on napthalen-1-yl-methylene-benzenesulfonohydrazide (NMBSH) derivatives <italic>via</italic> an electrochemical approach.
Triple peaks plasmonic thermal emitter with selectable wavelength using periodic block pattern as top layer (2011)

A plasmonic thermal emitter (PTE) with periodic block pattern as top layer was investigated. It is found that by adjusting the length and orientation of the rectangle metallic islands inside the block, three polarization-dependent peaks can be obtained in the thermal radiation spectra. The individual mode can be extracted according to different polarization by an external polarizer. Thus, a triple - spectral response PTE can be designed by tuning the appropriate dimensions of the block pattern.
Mechanisms of Aminoglycoside Ototoxicity and Targets of Hair Cell Protection (2011)

Aminoglycosides are commonly prescribed antibiotics with deleterious side effects to the inner ear. Due to their popular application as a result of their potent antimicrobial activities, many efforts have been undertaken to prevent aminoglycoside ototoxicity. Over the years, understanding of the antimicrobial as well as ototoxic mechanisms of aminoglycosides has increased. These mechanisms are reviewed in regard to established and potential future targets of hair cell protection.
Validity of Clinical Trials of Antidepressants (2000)

The issue of bias or allegiance effects for both antidepressant and psychotherapy research is real. Investigators of all orientations must guard against potential bias. However, studies cited as supporting the questionable validity of antidepressant trials fail upon closer examination to support assertions that these trials are invalid.
Nanoscale Rotary Motors Driven by Electron Tunneling (2008)

We examine by semiclassical molecular dynamics simulations the possibility of driving nanoscale rotary motors by electron tunneling. The model systems studied have a carbon nanotube shaft with covalently attached "isolating" molecular stalks ending with "conducting" blades. Periodic charging and discharging of the blades at two metallic electrodes maintains an electric dipole on the blades that is rotated by an external electric field. Our simulations demonstrate that these molecular motors can be efficient under load and in the presence of noise and defects.
Data Mining Model for Money Laundering Detection in Financial Domain (2014)

One of the likeliest problems faced by the banks is the way the nature of money transaction takes place is not always known to the bank. One such problem consisting large amounts of money transferring through various accounts by the same person or entity is Money Laundering. Money laundering system is quite a convoluted process. It takes some understanding of the fund transferring activities at various stages. The system that works against Money laundering is Anti-Money Laundering (AML) system. The existing system for Anti-Money Laundering accepts bulk of data and converts it to large volumes reports that are tedious and topsy-turvy for a person to read without any help of software. Hence, the purpose of making decision within specified time span is de-facilitated. The basic motive behind designing a system is that it should either notify or generate alarm for Money Laundering process within time when the illicit actions are been carried out so that, some action can be taken or an decision could be made before the actual laundering task is completed. The Transaction flow analysis (TFA) is a system that facilitates the basic ideology of Anti-Money Laundering system. TFA consists of various segments those results in clusters of various sizes. However, the existing TFA system allows the data to be taken from a single entity may be bank or a financial institution. Also the cluster generated are large in volume hence the analyst sometime may find it difficult to analyze such huge amount of data. This project uses combination of TFA system with the system designed to extract customer behavior in order to make decision whether the customer is suspicious customer or not. Also this project will allow taking data as input from various sources, integrating and then performing operations on the data.
Valproic Acid I: Time Course of Lipid Peroxidation Biomarkers, Liver Toxicity, and Valproic Acid Metabolite Levels in Rats (2005)

A single dose of valproic acid (VPA), which is a widely used antiepileptic drug, is associated with oxidative stress in rats, as recently demonstrated by elevated levels of 15-F(2t)-isoprostane (15-F(2t)-IsoP). To determine whether there was a temporal relationship between VPA-associated oxidative stress and hepatotoxicity, adult male Sprague-Dawley rats were treated ip with VPA (500 mg/kg) or 0.9% saline (vehicle) once daily for 2, 4, 7, 10, or 14 days. Oxidative stress was assessed by determining plasma and liver levels of 15-F(2t)-IsoP, lipid hydroperoxides (LPO), and thiobarbituric acid reactive substances (TBARs). Plasma and liver 15-F(2t)-IsoP were elevated and reached a plateau after day 2 of VPA treatment compared to control. Liver LPO levels were not elevated until day 7 of treatment (1.8-fold versus control, p < 0.05). Liver and plasma TBARs were not increased until 14 days (2-fold vs. control, p < 0.05). Liver toxicity was evaluated based on serum levels of alpha-glutathione S-transferase (alpha-GST) and by histology. Serum alpha-GST levels were significantly elevated by day 4, which corresponded to hepatotoxicity as shown by the increasing incidence of inflammation of the liver capsule, necrosis, and steatosis throughout the study. The liver levels of beta-oxidation metabolites of VPA were decreased by day 14, while the levels of 4-ene-VPA and (E)-2,4-diene-VPA were not elevated throughout the study. Overall, these findings indicate that VPA treatment results in oxidative stress, as measured by levels of 15-F(2t)-IsoP, which precedes the onset of necrosis, steatosis, and elevated levels of serum alpha-GST.
Are Preflushes Really Contributing to Mud Displacement During Primary Cementing? (2007)

Abstract During a primary cementing operation, it is most of the time necessary to prevent direct contact between the drilling mud and the cement slurry that is to be placed in the wellbore. The reason is that these two fluids are usually incompatible. This incompatibility can manifest itself either as an accelerating effect, the drilling mud/cement mixtures having a shorter thickening time than the cement itself, which is obviously not acceptable, or as a viscosifying effect, the drilling mud/cement mixtures being more or much more viscous than any of the two uncontaminated fluids, which can be detrimental to the displacement process. To keep the drilling fluid and the cement slurry separated, low density and low viscosity fluids, that will be referred to as preflushes, are often pumped ahead of the cement slurry. Examples of such fluids are water, oil, or more advanced formulations which are usually called chemical wash. It was recognized relatively early that, to be efficient, preflushes should be in turbulent flow in the annulus for a minimum amount of time. In the early 90s the criteria for turbulence was refined by taking into account the eccentricity of the annulus on the flow regime. The objective of this paper is to illustrate what fluid displacement modeling is telling us about the efficiency of these preflushes. It will be shown that, in a number of cases, preflushes are not as effective as one would think at preventing direct contact between the drilling fluid and the cement slurry, even when industry accepted rules are used to design them. In such circumstances the cement slurry is actually displacing the drilling fluid, but there are risks associated with this situation as explained above. It is therefore suggested that preflushes should be used with more caution and replaced by weighted spacers, in particular in circumstances where good cement quality is mandatory up to the top of the cement column.
Compact EEPROM-based Weight Functions (1990)

We are focusing on the development of a highly compact neural net weight function based on the use of EEPROM devices. These devices have already proven useful for analog weight storage, but existing designs rely on the use of conventional voltage multiplication as the weight function, requiring additional transistors per synapse. A parasitic capacitance between the floating gate and the drain of the EEPROM structure leads to an unusual I-V characteristic which can be used to advantage in designing a compact synapse. This novel behavior is well characterized by a model we have developed. A single-device circuit results in a 1-quadrant synapse function which is nonlinear, though monotonic. A simple extension employing 2 EEPROMs results in a 2 quadrant function which is much more linear. This approach offers the potential for more than a ten-fold increase in the density of neural net implementations.
Short-Chain PEG Mixed Monolayer Protected Gold Clusters Increase Clearance and Red Blood Cell Counts (2011)

Monolayer-protected gold nanoparticles have great potential as novel building blocks for the design of new drugs and therapeutics based on the easy ability to multifunctionalize them for biological targeting and drug activity. In order to create nanoparticles that are biocompatible in vivo, polyethylene glycol functional groups have been added to many previous multifunctionalized particles to eliminate nonspecific binding. Recently, monolayer-protected gold nanoparticles with mercaptoglycine functionalities were shown to elicit deleterious effects on the kidney in vivo that were eliminated by incorporating a long-chain, mercapto-undecyl-tetraethylene glycol at very high loadings into a mixed monolayer. These long-chain PEGs induced an immune response to the particle presumably generating an anti-PEG antibody as seen in other long-chain PEG-ylated nanoparticles in vivo. In the present work, we explore the in vivo effects of high and low percent ratios of a shorter chain, mercapto-tetraethylene glycol within the monolayer using simple place-exchange reactions. The shorter chain PEG MPCs were expected to have better water solubility due to elimination of the alkyl chain, no toxicity, and long-term circulation in vivo. Shorter chain lengths at lower concentrations should not trigger the immune system to create an anti-PEG antibody. We found that a 10% molar exchange of this short-chain PEG within the monolayer met three of the desired goals: high water solubility, no toxicity, and no immune response as measured by white blood cell counts. However, none of the short-chain PEG mixed monolayer compositions enabled the nanoparticles to have a long circulation time within the blood as compared to mercapto-undecyl-ethylene glycol, which had a residence time of 4 weeks. We also compared the effects of a hydroxyl versus a carboxylic acid terminal functional group on the end of the PEG thiol on both clearance and immune response. The results indicate that short-chain-length PEGs, regardless of termini, increase clearance rates compared to the previous long-chain PEG studies, while carboxylated termini increase red blood cell counts at high loadings. Given these findings, short-chain, alcohol-terminated PEG, exchanged at 10%, was identified as a potential nanoparticle for further in vivo applications requiring short circulation lifetimes with desired features of no toxicity, no immune response, and high water solubility.
Classical Spins in Superconductors (1968)

It is shown that there exists a localized excited state in the energy gap in a superconductor with a classical spin. At finite concentration localized excited states around classical spins form an "impurity band". The process of growth of the "impurity band" and its effects on observable quantities are investigated.
Fault mechanisms from near-source data: joint inversion of S polarizations and P polarities (2007)

We propose a non-linear inversion method for studying the earthquake mechanism by combining the information carried by both S-wave polarizations and P-wave polarities from near-source records. The posterior probability of parameters (strike, dip and slip fault angles) for the given observational data sets is computed by using a Bayesian approach. The conditional probability density function of S polarizations given a model parameter set is defined assuming a Gaussian distribution for the expected errors. The P polarity information is taken into account in the form of a prior probability density function, which has been defined according to Brillinger, Udias & Bolt (1980). The method is based on the estimate by an exhaustive search of the posterior probability of model parameters. This probability is then represented by its projection on plane sections in the model space. This enables one to locate the maximum likelihood solutions, and to get a reliable estimate of the parameter correlation and resolution. Numerical examples and data analysis show that the addition of a few S polarizations to a P polarity data set greatly improves the resolution on the fault parameters.
Role of human major histocompatibility complex DQ molecules in superantigenicity of streptococcus-derived protein (1994)

Antigenicity of peptic extract from type 12 group A streptococci (PEAST12) for T cells was examined in major histocompatibility complex (MHC) class II transgenic mice. PEAST12 was mitogenic for murine T cells when antigen-presenting cells were obtained from human MHC (HLA)-DQ4 alpha beta transgenic mice or from DQ6 alpha beta transgenic mice but was not mitogenic in DR alpha transgenic, DR51 alpha beta transgenic, E alpha transgenic, or nontransgenic mice. In addition, PEAST12 showed mitogenicity for murine T cells in DQ4 alpha singly transgenic mice but not in DQ4 beta singly transgenic mice. T-cell stimulation by PEAST12 was unrestricted by but dependent on the expression of HLA-DQ molecules on antigen-presenting cells, and PEAST12 selectively activated T-cell receptor V beta 11-, V beta 15-, and V beta 18-positive T cells in mice. We propose that PEAST12 contains a superantigen which binds preferentially to the alpha-chain of HLA-DQ molecules. The well-known phenomenon that peptic extracts from group A streptococci are mitogenic in humans but not in mice is likely due to structural differences in MHC class II molecules between these two species of mammals.
A design of CMOS polycell for LSI circuits (1981)

We have designed CMOS polycells with a uniform height for LSI random logic circuits. The design objective was to minimize the product of propagation delay and chip area while allowing noise margins to be at least 25 percent of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">V_{dd}</tex> . Designable parameters were identified to be channel widths in <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p</tex> -type and <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</tex> -type transistors. Analytical models were derived to show the existence of an optimal solution point. Physical interpretations of models were also given. SPICE was used to simulate propagation delays and noise margins in inverter (INR), 2- and 3-input NAND and NOR gates under worst-case conditions. The chip performance of polycell-based CMOS circuits was then estimated by averaging performances of these five logic gates. With <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3.5-{\mu}m</tex> design rules, the channel widths in <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p</tex> -channel and <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</tex> -channel transistors were designed to be <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">35{\mu}m</tex> and <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">17{\mu}m</tex> , respectively.
Fractal properties of chaotic dynamical systems in reverse time and its applications (2006)

The dynamical process properties of chaotic discrete map in reverse time is considered. This approach is connected with inverse problem of nonlinear dynamics. The fractal structure of reverse iteration points is investigated. Several types of ordering of the reverse points manifold are proposed.
An analysis of the effect of shield length on the performance of magnetoresistive heads (1978)

Output voltages and pulse shapes from shielded magnetoresistive read heads of the finite pole-tip configuration were calculated using a numerical solution of the integral form of Maxwell's equations. Isolated pulse shapes and "all ones" output voltage versus transition density are shown as a function of shield length and permeability.
High affinity binding of [<sup>3</sup>H]‐tyramine in the central nervous system (1986)

Optimum assay conditions for the association of [3H]-para-tyramine [( 3H]-pTA) with rat brain membranes were characterized, and a saturable, reversible, drug-specific, and high affinity binding mechanism for this trace amine was revealed. The binding capacity (Bmax) for [3H]-pTA in the corpus striatum was approximately 30 times higher than that in the cerebellum, with similar dissociation constants (KD). The binding process of [3H]-pTA involved the dopamine system, inasmuch as (a) highest binding capacity was associated with dopamine-rich regions; (b) dopamine and pTA equally displaced specifically bound [3H]-pTA; (c) there was a severe loss in striatal binding capacity for [3H]-pTA and, reportedly, for [3H]-dopamine, following unilateral nigrostriatal lesion; (d) acute in vivo reserpine treatment markedly decreased the density of [3H]-pTA and, reportedly, of [3H]-dopamine binding sites. In competition experiments [3H]-pTA binding sites, though displaying nanomolar affinity for dopamine, revealed micromolar affinities for the dopamine agonists apomorphine and pergolide, and for several dopamine antagonists, while having very high affinity for reserpine, a marker for the catecholamine transporter in synaptic vesicles. The binding process of [3H]-pTA was both energy-dependent (ouabain-sensitive), and ATP-Mg2+-insensitive; furthermore, the potencies of various drugs in competing for [3H]-pTA binding to rat striatal membranes correlated well (r = 0.96) with their reported potencies in inhibiting [3H]-dopamine uptake into striatal synaptosomes. It is concluded that [3H]-pTA binds at a site located on/within synaptic vesicles where it is involved in the transport mechanism of dopamine.
Historical, Descriptive and Dynamic Linguistics (1959)

The neo-grammarian school (1870-1900) established a conception of linguistics as a science based on detailed observation of language and accurate formulation of observed processes. This has led to a shift of attention from historical studies to the investigation of living language, which is better able to meet the requirements of this conception. The validity of traditional historical methods of reconstruction and explanation has appeared increasingly suspect. The insight of descriptive structural linguistics may help to refine the formulation of historical systems and processes, but cannot establish their validity, nor provide more than a most restricted dynamic of language change. This must spring from the establishment of the dimensions of variation within a language community, the conditions of usage and balance of apparently competing forms (linguistic ecology), and the observation of the action of selection pressures upon their distribution.
Induction of the Intronic Enhancer of the Human Ciliary Neurotrophic Factor Receptor (CNTFRä) Gene by the TR4 Orphan Receptor (1997)

A conserved hormone response element, CNTFR-DR1 (5'-AGGTCAGAGGTCAGG-3'), has been identified in the 5th intron of the alpha component of the ciliary neurotrophic factor receptor (CNTFRalpha) gene for the human TR4 orphan receptor (TR4). Electrophoretic mobility shift assay showed a specific binding with high affinity (Kd = 0.066 nM) between TR4 and the CNTFR-DR1. A reporter gene assay using chloramphenicol acetyltransferase demonstrated that the 5th intron of CNTFRalpha has an enhancer activity which could be induced by TR4 in a dose-dependent manner. Furthermore, our in situ hybridization data showed that abundant TR4 transcripts were detected in adult brain, in regions of cortical and hippocampal neurons, as well as in many developing neural structures, including brain, spinal cord, ganglia (sympathetic and sensory), and neuronal epithelia (retinal, otic, olfactory, and gustatory). The striking similarities in the expression patterns of TR4 and CNTFRalpha in the developing and postnatal nervous systems further support the potential role of TR4 in neurogenesis. Collectively, these data suggest that the human CNTFRalpha gene could represent the first identified neural-specific gene induced by TR4.