gebhart/patrepeval huggingface dataset:
Structural and Electrical Properties of Solution-Processed Gallium-Doped Indium Oxide Thin-Film Transistors (2011)

We fabricated solution-processed gallium-doped indium oxide (GIO) thin-film transistors (TFTs). The electrical property, crystallinity, and transmittance were investigated as a function of gallium content. Varying the gallium/indium ratio is found to have a significant effect on structural and electrical properties of thin films. The shrinkage of the lattice of a GIO film originates from substitution of Ga on In sites in the In 2 O 3 lattice, which was verified by X-ray diffraction (XRD) analysis. By increasing the gallium ratio of the channel material, the GIO film shows an amorphous phase. The optimized GIO film (Ga/In= 0.35) has an electron mobility of 3.59 cm 2 V -1 s -1 , a threshold voltage of 0.1 V, an on/off current ratio of 8.2×10 7 , and a subthreshold slope of 0.9 V/decade, and is highly transparent (∼92%) in the visible region.
Developing an efficient and reproducible conjugation-based gene transfer system for bifidobacteria (2012)

Bifidobacteria are widely used as probiotics and have attracted increasing research interest worldwide. However, molecular techniques are still very scarce mainly due to the low efficiencies and strain-specific electroporation protocols that have been developed. Bacterial conjugation enables the transfer of genetic material among a relatively wide range of organisms and with virtually no size limitation. A conjugation protocol was developed based on the RP4 conjugative machinery in the Escherichia coli strain WM3064(pBB109). Using this machinery, the newly constructed transmissible E. coli-Bifidobacterium shuttle vector, pDOJHR-WD2, was successfully and consistently transferred into several strains representing four Bifidobacterium species at efficiencies which correlated with the E. coli to bifidobacteria ratios. Higher ratios were found to significantly improve transfer frequency per recipient, with almost 100 % transfer frequency occurring when the ratio was 10(5) : 1. The incompatible resident plasmid, pDOJH10S, in Bifidobacterium longum DJO10A was able to coexist, albeit at lower copy numbers, with the incoming vector pDOJHR-WD2 even though they possess the same ori. In some cases the copy number of this resident plasmid was too low to observe via gel electrophoresis, but it could be detected by Southern hybridization. Plasmid curing resulted in a strain, DJO10A-W3, that had lost both plasmids and this showed a one-log increase in conjugation efficiency due to the lack of plasmid incompatibility. In conclusion, this novel conjugative gene transfer protocol can be used for the introduction of genetic material (without size restriction) into Bifdobacterium species and is particularly useful for strains that are recalcitrant to electroporation.
Natural killer cells from epithelial ovarian cancer patients exhibit an altered phenotype and bind to MUC16 (2007)

5120 Natural killer (NK) cells are important components of innate immunity and are vital in anti-tumor responses. They are regulated through a delicate balance of cell-surface activating and inhibitory receptors. NK cells in epithelial ovarian cancer (EOC) have not been exhaustively studied. In our previous studies, we have shown that MUC16, a high molecular weight mucin overexpressed by ovarian tumors, inhibits NK cell cytolytic function and downregulates CD16, an activating receptor present on NK cells. We hypothesized, therefore, that MUC16 and other factors could be affecting the phenotype of NK cells in cancer patients. In order to study this further, we obtained peritoneal fluid (PF) and peripheral blood (PB) from nine cancer patients and PB from three healthy donors. Lymphocytes were isolated from these three sample types and stained with a panel of antibodies against numerous activating and inhibitory NK cell receptors. Multi-color flow cytometry was performed on the LSR II (Beckton Dickenson), and the data was analyzed using FlowJo (TreeStar) software. Normally, the majority of circulating peripheral blood (PB) human NK cells carry the CD56dim/CD16bright phenotype, which is capable of cytolytic activity. Small numbers of PBNK cells in healthy donors have a CD56bright/CD16dim phenotype, which do not exhibit high cytolytic responses. PBNK cells from EOC patients also carry the normal CD56dim/CD16bright phenotype. However, we have found that a subset of NK cells in the PF of patients with EOC show a 28% increase (p
Obesity, metabolic syndrome and sleep apnoea: all pro‐inflammatory states (2006)

Obesity is associated with significant morbidity and mortality and is increasing in prevalence worldwide. Associated conditions include insulin resistance (IR), diabetes, hypertension and dyslipidaemia; a clustering of these has recently been termed as metabolic syndrome. Weight gain is a major predictor of the metabolic syndrome with waist circumference being a more sensitive indicator than body mass index as it reflects both abdominal subcutaneous adipose tissue and visceral adipose tissue (VAT). VAT has more metabolic activity and secretes a number of hormones and pro-inflammatory cytokines which are linked with the metabolic abnormalities listed above. Central obesity also increases the risk of obstructive sleep apnoea syndrome (OSAS), where the sleep disordered breathing may also independently lead to/or exacerbate IR, diabetes and cardiovascular risk. The contribution of OSAS to the metabolic syndrome has been under-recognized. The putative mechanisms by which OSAS causes or exacerbates these other abnormalities are discussed. We propose that activation of nuclear factor kappa B by stress hypoxia and/or by increased adipokines and free fatty acids released by excess adipose tissue is the final common inflammatory pathway linking obesity, OSAS and the metabolic syndrome both individually and, in many cases, synergistically.
A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin (2015)

Neuropathic vulvodynia is a state of vulval discomfort characterized by a burning sensation, diffuse pain, pruritus or rawness with an acute or chronic onset. Diabetes mellitus may cause this type of vulvar pain in several ways, so this study was conducted to evaluate streptozotocin-induced diabetes as a neuropathic pain model for vulvodynia in female rats. The presence of streptozotocin (50 mg/kg i.p.)-induced diabetes was initially verified by disclosure of pancreatic tissue degeneration, blood glucose elevation and body weight loss 5-29 days after a single treatment. Dynamic (shortened paw withdrawal latency to light brushing) and static (diminished von Frey filament threshold pressure) mechanical allodynia was then confirmed on the plantar foot surface. Subsequently, both static and dynamic vulvodynia was detected by application of the paradigm to the vulval region. Systemic gabapentin (75 mg/kg, i.p.) and topical gabapentin (10 % gel) were finally tested against allodynia and vulvodynia. Topical gabapentin and the control gel vehicle significantly increased paw withdrawal threshold in the case of the static allodynia model and also paw withdrawal latency in the model for dynamic allodynia when compared with the streptozotocin-pretreated group. Likewise, in the case of static and dynamic vulvodynia, there was a significant antivulvodynia effect of systemic and topical gabapentin treatment. These outcomes substantiate the value of this model not only for allodynia but also for vulvodynia, and this was corroborated by the findings not only with systemic but also with topical gabapentin.
Learning from the genome sequence of <i>Mycobacterium tuberculosis</i> H37Rv (1999)

Mycobacterium tuberculosis, the scourge of humanity, is one of the most successful and scientifically challenging pathogens of all time. To catalyse the conception of new prophylactic and therapeutic interventions against tuberculosis, and to enhance our understanding of the biology of the tubercle bacillus, the complete genome sequence of the most widely used strain, H37Rv, has been determined. Bioinformatic analysis led to the identification of approximately 4000 genes in the 4.41 Mb genome sequence and provided fresh insight into the biochemistry, physiology. genetics and immunology of this much-feared bacterium. Genomic information is centralised in TubercuList (http://www.pasteur.fr/Bio/TubercuList/).
Computer vision based reliability control for electromechanical dice gambling machine (2005)

In our paper we present a complete overview of a reliability control module for an electro-mechanical dice gambling machine based on computer vision principles. We particularly discuss the fundamental, heavily utilized function of color difference, which forms a basis for fast, efficient and parameterized chroma-key applications. We also explain the dice location estimation solution and the final template matching phase of number detection. In the conclusion we discuss some issues and problems which are still left open but should be solved by the project team.
Microscale and Nanoscale Thermal Characterization Techniques (2007)

In this paper the authors review various microscale and nanoscale thermal characterization techniques that could be applied to active and passive devices. Solid-state micro refrigerators on a chip can provide a uniform and localized temperature profile and they are used as a test vehicle in order to compare the resolution limits of various microscale techniques. After a brief introduction to conventional micro thermocouples and thermistor sensors, various contact and contactless techniques will be reviewed. Infrared microscopy is based on thermal emission and it is a convenient technique that could be used with features tens of microns in size. Resolution limits due to low emissivity and transparency of various materials and issues related to background radiation will be discussed. Liquid crystals that change color due to phase transition have been widely used for hot spot identification in integrated circuit chips. The main problems are related to calibration and aging of the material. Micro Raman is an optical method that can be used to measure absolute temperature. Micron spatial resolution with several degrees temperature resolution has been achieved. Thermoreflectance technique is based on the change of the sample reflection coefficient as a function of temperature. This small change in 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> -10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-5</sup> range per degree is typically detected using lock-in technique when the temperature of the device is cycled. Use of visible and near IR wavelength allows both top surface and through the substrate measurement. Both single point measurements using a scanning laser and imaging with CCD or specialized lock-in cameras have been demonstrated. For ultrafast thermal decay measurement, pump-probe technique using nanosecond or femtosecond lasers have been demonstrated. This is typically used to measure thin film thermal diffusivity and thermal interface resistance. The spatial resolution of various optical techniques can be improved with the use of tapered fibers and near field scanning microscopy. While sub diffraction limit structures have been detected, strong attenuation of the signal reduces the temperature resolution significantly. Scanning thermal microscopy which is based on nanoscale thermocouples at the tip of atomic force microscope has had success in ultra high spatial resolution thermal mapping. Issues related to thermal resistance between the tip and the sample and parasitic heat transfer paths will be discussed
Pharmacological Studies on<i>Linderae umbellatae</i>Ramus, IV*. Effects of Condensed Tannin Related Compounds on Peptic Activity and Stress-Induced Gastric Lesions in Mice (1985)

Nine condensed tannin related compounds isolated from LINDERAE UMBELLATAE Ramus, (+)-catechin ( 1), (-)-epicatechin ( 2), proanthocyanidin B-1 ( 3), B-2 ( 4), B-4 ( 5), trimer A ( 6), trimer B ( 7), cinnamtannin B (1) ( 8) and cinnamtannin D (1) ( 9), were tested for their effects on peptic activity and stress-induced gastric lesions in mice. Peptic activity of rat gastric juice was suppressed by 6 and 7 IN VITRO, and slightly suppressed by 8 and 9. In pylorus-ligated mice, these compounds, except for 4, administered orally exhibited anti-peptic activity. Pretreatments of 4,6 and 7 orally protected mice against stress-induced gastric lesions. Effects of these compounds on digestive systems were dìscussed.
Adrenal insufficiency in Smith‐Lemli‐Opitz syndrome (1999)

We describe three unrelated patients with adrenal insufficiency and RSH or Smith-Lemli-Opitz syndrome (SLOS), a disorder due to deficient synthesis of cholesterol. These patients presented with hyponatremia, hyperkalemia, and decreased aldosterone-to-renin ratio, which is a sensitive measure of the renin-aldosterone axis. All patients had profound serum total cholesterol deficiency (14–31 mg/dl) and marked elevation of 7-dehydrocholesterol (10–45 mg/dl). Two patients were newborn infants with 46, XY karyotypes and complete failure to masculinize; one of these patients also had cortisol deficiency. Both patients died within 10 days of birth of cardiopulmonary complications while on adrenal replacement therapy. The third patient diagnosed with SLOS at birth presented at age 7months with fever and diarrhea and was noted to have profound hyponatremia. This patient is maintaining normal serum electrolytes on mineralocorticoid replacement. We conclude that adrenal insufficiency may be a previously undetected and treatable manifestation in SLOS. We hypothesize that deficiency of cholesterol, an adrenal hormone precursor, may lead to insufficient synthesis of adrenal steroid hormones. Am. J. Med. Genet. 82:382–384, 1999. © 1999 Wiley-Liss, Inc.
Visuospatial Short-Term Memory Explains Deficits in Tower Task Planning in High-Functioning Children with Autism Spectrum Disorder (2010)

Previous findings on planning abilities in individuals with high-functioning autism spectrum disorder (HFA) are inconsistent. Exploring possible reasons for these mixed findings, the current study investigated the involvement of memory in planning performance in 15 children with HFA and 17 typically developing controls. In addition to planning abilities (measured with the Tower of London), short-term memory and delayed recall for verbal as well as visuospatial material were assessed. Findings suggest that particularly reduced efficiency in visuospatial short-term memory is associated with Tower task planning deficits in children with HFA.
Effect of Low Cetane Fuels on Diesel Engine Performance 2-Combustion Performance of a Detroit Diesel 3-71 Engine (1985)

<div class="htmlview paragraph">Four experimental diesel fuels with cetane numbers (CN) of 40, 37, 35 and 27 have been tested in a Detroit Diesel Allison 3-71 engine using the standard N65 injectors. The 35 CN fuel was a blend of distillates from conventional and tar sands crude with hydrogen treated cat-cracked stock. This provided a fuel typical of the 1990's and beyond, with substantial levels of aromatic and cracked components. The 27 CN fuel was a blend of the same components as the 35 CN fuel only with a larger portion of the hydrogen treated cat-cracked component. The 40 CN fuel was identical to the 35 CN fuel with a .2% DII-3 Diesel Ignition Improver. The 37 CN fuel was a blend of Canadian winter diesel fuel oil and 24% Light Cycle Oil (LCO), The four experimental fuels and one reference fuel were tested at four load levels at each of three engine speeds. The performance and combustion characteristics were compared with the physical and chemical fuel properties.</div>
The <i>H-2</i> haplotype of a thymus graft influences the <i>Ir</i> gene regulated IgG3, IgG1, IgG2b, and IgG2a anti-(T,G)-A--L antibody responses of high-responder F1.nude mice. (1982)

In order to examine whether the H-2 haplotype of a thymus graft influences the levels of IgG3, IgG1, IgG2b, and IgG2a antibodies produced in an in vivo response to antigens under immune response (Ir) gene control, genotypic high-responder (H-2b X H-2k)F1.nude mice were grafted with thymuses from irradiated, neonatal low-responder (H-2k) or high-responder (H-2b or (H-2k X H-2b)F1) mice and immunized with (T,G)-A--L. All IgG antibody responses to (T,G)-A--L in high-responder mice were shown to be thymus dependent. The majority of F1.nude mice grafted with thymuses from high-responder haplotype donors produced high-responder levels of IgG anti-(T,G)-A--L antibodies. Conversely, the majority of F1.nude mice grafted with thymuses from low-responder haplotype donors gave low-responder phenotypic patterns. The modulation of the Ir gene phenotype was not restricted to a particular IgG isotype, but affected IgG3, IgG1, IgG2b, and IgG2a. The F1 . nude mice grafted with low-responder haplotype thymuses were able to produce IgG1, IgG3, and IgG2b antibodies to sheep erythrocytes, a thymus-dependent (TD) antigen not under overt Ir gene control. Circulating peripheral T cells were shown to be of host origin. By these criteria, the thymus grafts did enable F1.nude mice to respond to a TD antigen. These results support the concept that thymic H-2 determinants are involved in at least the selection of H-2 restricted T cell subsets, if not also the derivation of the T cell receptor repertoire for self and/or antigen recognition.
Microstructure control of medium carbon steel joints by low-temperature linear friction welding (2019)

Medium carbon steel sheets of 2.6 mm thick were successfully welded by linear friction welding at various frequencies and applied pressures. The welding temperature decreased with the decreasing frequency, but unexpectedly with the increasing applied pressure. A medium carbon steel joint with no martensitic transformation could be obtained at a welding temperature below the A1 point under the conditions of low frequency and high applied pressure. Moreover, the welding temperature evolution was found to be correlated with the behaviour of the flash expelling at the welding interface. It was revealed that the welding temperature can be determined as the temperature at which the ultimate tensile strength of the interface material decreased below the applied pressure.
A Simple Preparation of Amides from Acids and Amines by Heating of Their Mixture (1993)

Abstract Heating a mixture of an amine and an acid is demonstrated as the method of choice for the preparation of many amides. The yields depend on the physical properties and thermal stability of the reactants and range from good to excellent. The ideal reactants should have melting points below 200 °C, should not be highly volatile and should be thermally stable at that temperature for 30 minutes. Some of those disadvantages can be overcome by using acid esters instead of an acid in the reaction. The method stands out among the others by its simplicity, low cost and short reaction time. Also it can be performed in very large scale, does not require solvent and special purification of the reactants.
A Systematic Procedure for the Analysis of Multiply Branched Acoustic Transmission Lines (1987)

Research Papers A Systematic Procedure for the Analysis of Multiply Branched Acoustic Transmission Lines W. Eversman W. Eversman Department of Mechanical and Aerospace Engineering, University of Missouri—Rolla and AC Spark Plug Division, General Motors Corporation Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information W. Eversman Department of Mechanical and Aerospace Engineering, University of Missouri—Rolla and AC Spark Plug Division, General Motors Corporation J. Vib., Acoust., Stress, and Reliab. Apr 1987, 109(2): 168-177 (10 pages) https://doi.org/10.1115/1.3269410 Published Online: April 1, 1987 Article history Received: August 1, 1986 Online: November 23, 2009
The doping of the polyimide alignment layer by semiconductor quantum dots (2013)

We investigated the electro-optic properties of nematic liquid crystal cells oriented by polyimide (PI) layer doped with 3.5 nm semiconductor quantum dots (QDs) CdSe/ZnS at concentrations of 0.05 and 0.1 wt. %. It is shown that doping PI orienting layer by QDs reduces the permittivity and the phase delay, as well as increases the electrical resistance of the cells. Also we observed deceleration of liquid crystal (LC) optical response caused by the screening effect of the orienting layer.
Effects of local anesthetics on human platelets: filopodial suppression and endogenous proteolysis (1979)

Agents that affect platelet shape may be useful in understanding the mechanism of shape change; for this reason the effects of local anesthetics are worthy of further study. Local anesthetics cause platelets to retract filopodia. At short time intervals (up to about 30 min) and low concentrations of the drugs, the filopodia are reextended when the platelets are gel filtered with eluant free of anesthetic. At longer time intervals (1–2 hr) or higher drug concentrations, the retraction becomes irreversible. When the polypeptide composition of the total platelet lysate was examined on SDS gels, proteolysis of two high molecular weight bands was seen when the suppression became irreversible. These polypeptides, estimated as 250,000 and 230,000 daltons, were major components of a precipitate that formed when platelets were lysed at low ionic strength and were also enriched in a “cytoskeletal” preparation made by lysing platelets attached to glass beads and analyzing the adherent residue. Electron micrographs of platelets lysed on surfaces showed an intermeshed network of filaments to be a major component of the residue. The results suggest that the proteins comprised of these bands may be part of the cytoskeletal system and that their integrity may be necessary for the platelet to reextend filopodia following suppression.
Groupware and authoring (1996)

Introduction. Reviews and Views. Studying Users. New Tools and Users. New Tools. Commercial Systems and Experiences.
AUTHOR'S PREFACE (2010)

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Activation of C Atoms Implanted into GaAs Annealed with Highly As-Doped a-Si:H Films (2002)

Carbon-implanted GaAs was annealed by encapsulating its surface with a highly arsenic-doped hydrogenated amorphous silicon film. The annealed samples had very similar distribution profiles of the implanted C atoms as the as-implanted sample, whereas carriers were measured only in a shallow region near the surface. The implant dose and annealing temperature dependences of the sheet carrier concentrations were approximately the same as that for photoluminescence originating in the electron transition from the conduction band into the C acceptor level. © 2002 The Electrochemical Society. All rights reserved.