gebhart/patrepeval huggingface dataset:
Mobility Pattern Aware Routing in Mobile Ad Hoc Networks (2003)

A Mobile ad hoc network is a collection of wireless nodes, all of which may be mobile, that dynamically create a wireless network amongst them without using any infrastructure. Ad hoc wireless networks come into being solely by peer-to-peer interactions among their constituent mobile nodes, and it is only such interactions that are used to provide the necessary control and administrative functions supporting such networks. Mobile hosts are no longer just end systems; each node must be able to function as a router as well to relay packets generated by other nodes. As the nodes move in and out of range with respect to other nodes, including those that are operating as routers, the resulting topology changes must somehow be communicated to all other nodes as appropriate. In accommodating the communication needs of the user applications, the limited bandwidth of wireless channels and their generally hostile transmission characteristics impose additional constraints on how much administrative and control information may be exchanged, and how often. Ensuring effective routing is one of the greatest challenges for ad hoc networking. As a practice, ad hoc routing protocols make routing decisions based on individual node mobility even for applications such as disaster recovery, battlefield combat, conference room interactions, and collaborative computing etc. that are shown to follow a pattern. In this thesis we propose an algorithm that performs routing based on underlying mobility patterns. A mobility pattern aware routing algorithm is shown to have several distinct advantages such as (a) A more precise view of the entire network topology as the nodes move (b) A more precise view of the location of the individual nodes (c) Ability to predict with reasonably accuracy the future locations of nodes (d) Ability to switch over to an alternate route before a link is disrupted due to node movements.
Anterior cruciate ligament reconstruction the two-incision technique. (2002)

Historically, the two-incision technique for anterior cruciate ligament (ACL) reconstruction was the standard of practice. It allows predictable, near-anatomic placement of the femoral tunnel and provides highly reproducible results with few complications. There are several major advantages of the two-incision technique over endoscopic methods. These include consistent femoral tunnel placement, elimination of concern for "blowing out the back wall," elimination of the problem of graft-tunnel mismatch, elimination of the problem of screw divergence, and ease of use for revision ACL reconstruction procedures. The angle of the ACL graft is also more anatomic, matching the angle of the native ACL. In this chapter we present our technique for reconstruction of the ACL using the two-incision approach. Indications for its use are discussed. Advantages and disadvantages of the two-incision method compared with the all-endoscopic approach are reviewed.
Updates on stem cells and their applications in regenerative medicine (2008)

Stem cells have the capacity for self-renewal and capability of differentiation to various cell lineages. Thus, they represent an important building block for regenerative medicine and tissue engineering. These cells can be broadly classified into embryonic stem cells (ESCs) and non-embryonic or adult stem cells. ESCs have great potential but their use is still limited by several ethical and scientific considerations. The use of bone marrow-, umbilical cord-, adipose tissue-, skin- and amniotic fluid-derived mesenchymal stem cells might be an adequate alternative for translational practice. In particular, bone marrow-derived stem cells have been used successfully in the clinic for bone, cartilage, spinal cord, cardiac and bladder regeneration. Several preclinical experimental studies are under way for the application of stem cells in other conditions where current treatment options are inadequate. Stem cells can be used to improve healthcare by either augmenting the body's own regenerative potential or developing new therapies. This review is not meant to be exhaustive but gives a brief outlook on the past, present and the future of stem cell-based therapies in clinical practice.
Control of Voltage Source Inverter Using Multidimensional Feedback Quantization Modulator (2010)

This paper describes a novel switching signal generator for three-phase voltage source inverters. Unlike conventional space-vector pulsewidth modulation (SVPWM) which achieves three-phase input voltage by a combination of the basic space vectors, the proposed scheme produces optimal switching commands to minimize the filtered measure of quantization error. Under specific selections of the filter matrix and the quantization scheme, it is shown that the proposed modulator is equivalent to SVPWM. An experimental platform is built to verify the effectiveness of the proposed scheme. It is shown that the switching number of the proposed method is reduced without sacrificing the harmonic distortion within the input frequency band under various reference signals.
Designs of multipass optical configurations based on the use of a cube corner retroreflector in the interferometer (2011)

We describe designs of the multipass optical configurations of an interferometer with high spectral resolution with respect to 6, 12, and 24 times more optical passes than the conventional Michelson interferometer. In each design, a movable cube corner retroreflector is combined with a folding reflector group (FRG) as the interferometer's moving combination to implement the multipass optical configuration with the characteristic of surface division. Analyses reveal that when there are 12 or more optical passes, the net effect of the ray's angular deviation of the entire moving combination amounts to only the alignment error of one of the reflectors in the FRG, demonstrating the self-aligning property of the interferometer.
Global gene expression analysis of cell-free RNA in amniotic fluid from women destined to develop preeclampsia (2019)

Preeclampsia (PE) is a disorder specific to pregnancy characterized by new-onset hypertension and proteinuria after 20 weeks of gestation. There is no definite treatment for PE except delivery of the placenta. The purpose of this study was to elucidate the biological pathways involved in the development of PE and to discover a novel biomarker for PE by performing global gene expression analysis of amniotic fluid cell-free RNA.The participants were recruited from the Department of Obstetrics and Gynecology of CHA Gangnam Medical Center (Seoul, Korea) between March 2014 and February 2015. Eight samples were collected from 8 subjects at second trimester who were later diagnosed with PE. From the amniotic fluid samples, cell-free RNA extraction was performed and gene expression was analyzed using the GeneChip PrimeView Array. Transcriptome data previously analyzed by our group from 9 euploid mid-trimester amniotic fluid samples were used as the control for comparative analysis. Functional analysis of the probe sets was performed using the online Database for Annotation, Visualization, and Integrated Discovery (DAVID) toolkit 6.7.We identified 1841 differentially expressed genes (DEGs) between the PE group and the control. Of these, 1557 genes were upregulated in the PE group, while 284 genes were upregulated in the control. The functional annotation of DEGs identified specific enriched functions such as "transport," "signal transduction," and "stress response." Functional annotation clustering with enriched genes in the PE group revealed that translation-related genes, cell-cell adhesion genes, and immune-related genes were enriched. KEGG pathway analysis showed that several biological pathways, including the ribosome pathway and various immune pathways, were dysregulated. Several genes, including RPS29, IGF-2, and UBC, were significantly upregulated in PE, up to tenfold.This study provides the first genome-wide expression analysis of amniotic fluid cell-free RNA in PE. The results showed that gene expression involving the ribosome pathway and immunologic pathways are dysregulated in PE. Our results will aid in understanding the underlying pathogenesis of PE.
Hypochlorous and Peracetic Acid Induced Oxidation of Dairy Proteins (2011)

Hypochlorous and peracetic acids, both known disinfectants in the food industry, were compared for their oxidative capacity toward dairy proteins. Whey proteins and caseins were oxidized under well controlled conditions at pH 8 as a function of the sanitizing concentration. Different markers for protein oxidation were monitored. The results established that the protein carbonyl content was a rather unspecific marker for protein oxidation, which did not allow one to differentiate the oxidant used especially at the lower concentrations. Cysteine, tryptophan, and methionine were proven to be the most vulnerable amino acids for degradation upon hypochlorous and peracetic acid treatment, while tyrosine was only prone to degradation in the presence of hypochlorous acid. Hypochlorous acid induced oxidation gave rise to protein aggregation, while during peracetic acid induced oxidation, no high molecular weight aggregates were observed. Protein aggregation upon hypochlorous acid oxidation could primarily be linked to tryptophan and tyrosine degradation.
Diagnosis of Acid Placement From Temperature Profiles (2012)

Summary Optimum fluid placement is crucial for a successful acid-stimulation treatment, both for horizontal wells where there is a broad variation of reservoir properties along the wellbore and for vertical wells with multiple zones and/or extensive productive intervals. Recently, distributed-temperature-sensing technology has enabled us to observe dynamic temperature profiles along a wellbore during and after an acid treatment. This technology allows us to monitor and evaluate treatments in real time by capturing a sequence of temperature profiles at different times and inverting temperature response to acid-injection profiles. We have developed mathematical models to simulate the temperature behavior along a wellbore, horizontal or vertical, during and just after an acid treatment. This approach couples a wellbore model and a near-wellbore formation thermal model considering the effects of both mass and heat transfer between the wellbore and the formation. The models account for all significant thermal processes involved during a treatment, including heat of reaction, conduction, and convection. An inversion procedure is applied to interpret the acid-distribution profiles from the measured temperature profiles. For horizontal wells, the results indicate that the distribution of stimulation fluid along a lateral and the effectiveness of diversion processes during an acid treatment can be quantified in real time using distributed-temperature measurements. The model shows that the relative injectivities into different zones can be interpreted from the temperature response measured during injection. For vertical wells, we have focused on diagnosing the volume of acid placed in each zone from the flowback temperature history. During the flowback period, the zones that have taken more acid volume will show more heating because of reaction and will have higher temperature when hotter fluid enters the wellbore. This provides a mechanism to quantitatively determine the acid distribution. The methods developed from this study can help to diagnose and optimize acidizing design, and improve the efficiency of acid stimulation.
Oral Administration of CardioAid and Lunasin Alleviates Liver Damage in a High-Fat Diet Nonalcoholic Steatohepatitis Model (2017)

CardioAid and lunasin exerted hepatoprotective and glucose-protective effects in an HFD NASH model. These data and the high-safety profiles of CardioAid and Lunasin support their use in patients in the early stages of NASH to prevent deterioration due to the disease.
Porous, Platinum Nanoparticle-Adsorbed Carbon Nanotube Yarns for Efficient Fiber Solar Cells (2012)

Pt is a classical catalyst that has been extensively used in fuel cell and solar cell electrodes, owing to its high catalytic activity, good conductivity, and stability. In conventional fiber-shaped solar cells, solid Pt wires are usually adopted as the electrode material. Here, we report a Pt nanoparticle-adsorbed carbon nanotube yarn made by solution adsorption and yarn spinning processes, with uniformly dispersed Pt nanoparticles through the porous nanotube network. We have fabricated TiO(2)-based dye-sensitized fiber solar cells with a Pt-nanotube hybrid yarn as counter electrode and achieved a power conversion efficiency of 4.85% under standard illumination (AM1.5, 100 mW/cm(2)), comparable to the same type of fiber cells with a Pt wire electrode (4.23%). Adsorption of Pt nanoparticles within a porous nanotube yarn results in enhanced Pt-electrolyte interfacial area and significantly reduced charge-transfer resistance across the electrolyte interface, compared to a pure nanotube yarn or Pt wire. Our porous Pt-nanotube hybrid yarns have the potential to reduce the use of noble metals, lower the device weight, and improve the solar cell efficiency.
Built-In Multiband Antennas for Mobile Phone and WLAN Standards (2005)

Two novel miniature multiband antennas suitable for mobile phone and WLAN applications have been presented in this paper. The first antenna achieves low return loss and good efficiency in the GSM and the DCS/PCS/UMTS bands while the second structure covers the 5 GHz WLAN bands in addition with same performance.
GPS Interferometric Attitude and Heading Determination: Initial Flight Test Results (1991)

Attitude and heading determination using GPS interferometry is a well-understood concept. However, efforts have been concentrated mainly in the development of robust algorithms and applications for low-dynamic, rigid platforms (e.g., shipboard). This paper presents results of what is believed by the authors to be the first real-time flight test of a GPS attitude and heading determination system. Signals from four antennas are processed by a 24-channel GPS receiver. Data from the receiver are sent to a microcomputer for storage and further computations. Attitude and heading data are sent to a second computer for display on a software-generated artificial horizon. Demonstration of this technique proves its candidacy for augmentation of aircraft state estimation for flight control and navigation, as well as for numerous other applications.
Assignment of cloned genes to the seven electrophoretically separated Candida albicans chromosomes. (1988)

By using orthogonal-field alternating gel electrophoresis (OFAGE), field-inversion gel electrophoresis (FIGE), and contour-clamped homogeneous field gel electrophoresis (CHEF), we have clearly resolved 11 chromosomal bands from various Candida albicans strains. OFAGE resolves the smaller chromosomes better, while FIGE, which under our conditions causes the chromosomes to run in the reverse order of OFAGE, is more effective in separating the larger chromosomes. CHEF separates all chromosomes under some conditions, but these conditions do not often resolve homologs. The strains examined are highly polymorphic for chromosome size. Fourteen cloned Candida genes, isolated on the basis of conferral of new properties to or complementation of auxotrophic deficiencies in Saccharomyces cerevisiae, and three sequences of unknown function have been hybridized to Southern transfers of CHEF, FIGE, and OFAGE gels. Four sets of resolvable bands have been shown to be homologous chromosomes. On the basis of these data, we suggest that C. albicans has seven chromosomes. Genes have been assigned to the seven chromosomes. Two chromosomes identified genetically have been located on the electrophoretic karyotype.
New Results on the Old <i>k</i>-opt Algorithm for the Traveling Salesman Problem (1999)

Local search with k-change neighborhoods is perhaps the oldest and most widely used heuristic method for the traveling salesman problem, yet almost no theoretical performance guarantees for it were previously known. This paper develops several results, some worst-case and some probabilistic, on the performance of 2- and k-opt local search for the traveling salesman problem, with respect to both the quality of the solution and the speed with which it is obtained.
Modelling software components (2002)

Argues that precise visual modelling techniques are important for modelling large-scale software components, as they facilitate the core activities of component-based software development (CBSD): building, finding, adapting and assembling components. This paper argues for a carefully selected set of techniques based on the Unified Modelling Language (UML), to provide accessible yet precise component models. The authors then sketch a high-level reference model for CBSD to tease out exactly what is meant by the terms 'component', 'component adaptation' and 'component assembly'. The paper illustrates this reference model by giving examples of components and the transformations that can be applied to them, using precise visual models.
Dynamic load distribution in massively parallel architectures: the parallel objects example (2002)

The paper presents the mechanisms for dynamic load distribution implemented within the support for the Parallel Objects (PO for short) programming environment. PO applications evolve depending on their dynamic need of resources, enhancing application performance. The goal is to show how dynamic load distribution can be successfully applied on a massively parallel architecture.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A bone matrix calcification-initiator noncollagenous protein (1977)

When completely demineralized, the densely packed structure of bone matrix does not recalcify, neither in physiologic solutions in vitro nor in implants in vivo. Even when inorganic and organic calcification inhibitors (which normally are stored in bone matrix) are removed first by autolytic digestion in neutral buffers at 37C and then by sequential chemical extraction, implants of the EDTA insoluble residue will not recalcify after as long as 4 wk in a muscle pouch. However, if first demineralized in cold dilute HCl, second, extracted and autodigested in buffers solution at 37C, and then further extracted in EDTA and other solutions at 2C, a calcification initiator protein (Cp) is unmasked, and the residue will invariable recalcify. CIP, isolated by gel filtration and column chromatography, is a disulfide-bonded glycoprotein aggregate composed of subunites of a moleclar mass of 55,000. CIP is composed of a large proportion of acidic amino acids and has a calcium binding capacity of about 1.8 times greater than albumin. The affinity constant CaCIP, calculated by ultrafiltration of physiologic solutions of Ca2+, is log K, 2.9. Observations on implants of residues that containe a) CIP but not a bone morphogenetic property (BMP), B) BMP accompanied by CIP activity, or c) neither BMP nor CIP activity suggested that BMP covers CIP and that the two are attached to bone collagen in tandem. Whether CIP plays a part in calcification of the normal skeleton requires further investigation.
A Unified Approach to Heterogeneous Video-on-Demand Broadcasting (2008)

Video-on-demand (VoD) is an essential technology for many multimedia applications. However, it remains challenging to efficiently deliver on-demand streams to a large number of receivers in a heterogeneous network environment. Although a number of VoD broadcasting protocols have been proposed for heterogeneous receivers, these protocols considers only single-bit-rate VoD services, which cannot satisfy the diverse quality-of-service requirements of heterogeneous receivers. In this paper, we propose a unified approach to heterogeneous VoD broadcasting, called unified heterogeneous broadcasting (UHB). As a unified approach, UHB is design to integrate different VoD broadcasting protocols and different scalable video coding schemes. The main merits of UHB are threefold. First, unlike conventional VoD broadcasting protocols, UHB supports multiple-bit-rate VoD services. Second, UHB is capable of adapting to network bandwidth fluctuations. Third, UHB enables each heterogeneous receiver to obtain the best visual quality by selecting the optimum system joining time. Our performance evaluation results indicate that UHB is superior to conventional heterogeneous VoD broadcasting protocols under various network conditions.
Admittance control of a 1-DoF robotic arm actuated by BLDC motor (2012)

The aim of this paper is to analyze the admittance control of a single-axis mechanism actuated by brushless DC (BLDC) motor. There is also presented an examination of applied control architecture. Experiments consisted of the study of high-speed contact of the manipulator with infinitely rigid environment, as well as slow increase in force, which affected the manipulator. There are presented simulation results, as well as the practical study. The impedance controller drives the torque-controlled manipulator system. Force between the arm and the environment was estimated based on motor current. The paper shows from practical point of view how to efficiently steer BLDC motors with admittance controllers.
Patterns and Determinants of Prescribing for Parkinson’s Disease: A Systematic Literature Review (2019)

Since the discovery of levodopa (L-dopa) in 1967, the range of medications available to treat Parkinson's disease has increased significantly and guidance on the use, efficacy, and safety of these medications has evolved. To assess levels of adherence to national prescribing guidelines and awareness of changes in the efficacy and safety data published in the profiles of medications for the treatment of PD, we have reviewed studies on patterns and determinants of prescribing PD medications conducted in the last 50 years (since the discovery of L-dopa). A systematic literature review was conducted using EMBASE (1967 to March, 2018), Ovid MEDLINE(R) ALL (1967 to March 16, 2018), PsycINFO (1967 to the 2<sup>nd</sup> week of March, 2018), and PubMed to identify all studies measuring prescribing patterns of PD medication between 1967 and 2017. Study design, source of data, country, year of study, number of patients and/or prescriptions, unit of analysis, prescribing determinants, and percentage utilisation of PD medications were extracted where possible. 44 studies examining prescribing patterns and/or prescribing determinants across 17 countries were identified. Unsurprisingly, L-dopa was the most commonly prescribed medication in all studies, accounting for 46.50% to 100% of all prescriptions for PD. In several studies, the prescribing rate of ergot-derived dopamine agonists (DAs) decreased over time in concordance with guidance. In contrast, the prescribing rates of non-ergot DAs increased over the last ten years in most of the included studies. In examining prescribing factors, two major categories were exemplified, patients' factors and prescribers' factors, with patients' age being the most common factor that affected the prescription in most studies. In conclusion, L-dopa is now the most commonly prescribed medication for cases of PD but there is large variation in the prescribing rates of catechol-O-methyltransferase (COMT) inhibitors, monoamine oxidase B (MAO-B) inhibitors, amantadine, and anticholinergics between countries. New studies examining the effects of recent clinical trials and measuring the prescribing rates of newly approved medications are warranted.