gebhart/patrepeval huggingface dataset:
A214 Nonlinear dynamic properties of combustion oscillations in a lean premixed gas turbine combustor (2009)

Dynamic properties of combustion oscillations in a lean premixed gas turbine combustor have been experimentally investigated from the viewpoint of nonlinear dynamics based on chaos theory. As equivalence ratio φ increases from 0.45 to 0.50, the dynamic behavior of combustion oscillations undergoes a significant transition from low-dimensional chaos to periodic oscillation. The deterministic nature for shortly predicting the combustion oscillations sufficiently persists in the trajectories of phase space constructed from the time series of pressure fluctuations.
Monoclonal antibody 16D10 to the COOH-terminal domain of the feto-acinar pancreatic protein targets pancreatic neoplastic tissues (2009)

We have shown that the 16D10 antigen located on the mucin-like COOH-terminal domain of the feto-acinar pancreatic protein (FAPP) is expressed at the surface of human pancreatic tumor cell lines such as SOJ-6 cell line. Furthermore, an in vivo study indicates that targeting this cell-membrane glycopeptide by the use of the monoclonal antibody (mAb) 16D10 inhibits the growth of SOJ-6 xenografts in nude mice. To validate the potential use of the mAb16D10 in immune therapy, this study examined the expression of 16D10 antigens at the surface of human pancreatic adenocarcinomas versus control tissues. We examined the reactivity of mAb16D10 and mAb8H8 with pancreatic ductal adenocarcinomas (PDAC) compared with controls by using immunohistochemistry and confocal laser scanning microscopy. mAb8H8 does react with control or nontumoral human pancreatic tissues. mAb16D10 has a strong and specific reactivity with PDAC and does not react with other cancers of epithelia or normal tissues tested. Notable, mAb16D10 mostly recognizes membrane of tumoral cells. Furthermore, mAb8H8 and mAb16D10 recognized a protein of 110 to 120 kDa in homogenates of nontumoral and tumoral human pancreatic tissues, respectively. This size correlates with that of FAPP or with that of the normal counterpart of FAPP, the so-called bile salt-dependent lipase. The results suggest that mAb16D10 presents a unique specificity against PDAC; consequently, it could be effective in immune therapy of this cancer. Furthermore, mAb16D10 and mAb8H8 pair might be useful for diagnosis purpose in discriminating tumoral from nontumoral human pancreatic tissues.
[Correction of spectral interferences in inductively coupled plasma atomic emission spectrometry with a modified chemometric method based on matrix projection]. (1998)

A modified chemometric method based on matrix projection was developed to correct the spectral interferences in inductively coupled plasma atomic emission spectrometry (ICP-AES). The accuracy of the correction was significantly improved by reevaluating the residuals. The excellent analytical results for some rare earth elements proved the method fairly feasible.
Application of Directed Metallation in Synthesis, Part 2: An Expedient Synthesis of Methoxybenzo[b]thiophenes (2002)

A short, simple and expedient synthesis of substituted benzo[b]thiophenes involving directed ortho lithiation-side-chain deprotonation-cyclisation-reduction is described. This method is a valuable improvement over earlier syntheses of the same class of compounds, both with respect to the number of steps and overall yields.
The Emerging Science of Very Early Detection of Disease Outbreaks (2001)

A surge of development of new public health surveillance systems designed to provide more timely detection of outbreaks suggests that public health has a new requirement: extreme timeliness of detection. The authors review previous work relevant to measuring timeliness and to defining timeliness requirements. Using signal detection theory and decision theory, the authors identify strategies to improve timeliness of detection and position ongoing system development within that framework.
A Randomized Controlled Trial of Cash Incentives or Peer Support to Increase HCV Treatment for Persons With HIV Who Use Drugs: The CHAMPS Study (2019)

The registration data for the trial are in the ClinicalTrials.gov database, number NCT02402218.
The HDTV Camcorder and the March to Marketplace Reality (1998)

A complex 12-year development of high-definition television (HDTV) production standards has vied with consecutive generations of HDTV program origination equipment. While aspiring to the full promise of the ever-evolving standards, equipment designers have grappled with a multiplicity of marketplace realities as separately deifned by the world's broadcasters and program producers. HDTV program origination continues to be frustrated by unrealistic equipment costs and a lack of mobile battery-powered HDTV acquisition systems. The latter is central to the proper exploitation of the significant enhancement to television imagery latent within the technical parameters defined by the latest SMPTE 274M HDTV production standard. This paper describes a bold development thrust that sought to simultaneously lower costs and produce a high-performance, highly compact, HD acquisition system. The technological leap from contemporary HDTV cameras and digital recorders to an all-digital one-piece HD camcorder called for the best in engineering innovation, pragmatic design decisions, and a massive commitment to custom-built VLSI. This paper specifically describes the prototype of the 1920 × 1035 (SMPTE 260M) based camcorder. A modified product based on the later SMPTE 274M standard (1920 × 1080 format) will follow.
Thromboplastin immobilized on polystyrene surface exhibits kinetic characteristics close to those for the native protein and activates in vitro blood coagulation similarly to thromboplastin on fibroblasts (2010)

A method for transmembrane protein thromboplastin (tissue factor) immobilization on polystyrene surface is described. Tissue factor is the main activating factor launching the blood coagulation process. It is a cofactor of factor VIIa, the first protease in the cascade of coagulation reactions. The proposed method preserves kinetic characteristics specific for native tissue factor on the fibroblast surface. The kinetics of binding to factor VIIa and enzymic activity of the formed complex follow Michaelis-Menten kinetics, which is also characteristic of native complex. A small difference is that dissociation constant for tissue factor immobilized on polystyrene surface exceeds 2.7-fold that for native factor. The proposed technique of immobilization provides for protein density on the activating surface corresponding to the tissue factor density on the fibroblast surface. The immobilized tissue factor can be used to activate blood coagulation in methods simulating spatial dynamics of in vitro clot growth. Investigation in this direction will make it possible to register both hypo- and hypercoagulation states of the system. This approach is advantageous over traditional methods of estimation of the coagulation system conditions, which mainly register only hypocoagulation. Investigation of the storage time has shown that activators containing immobilized tissue factor can be stored and used during for at least 100 days in the method studying spatial dynamics of fibrin clot formation.
PUSHING THE LIMITS, EPISODE 2: K2 OBSERVATIONS OF EXTRAGALACTIC RR LYRAE STARS IN THE DWARF GALAXY LEO IV (2015)

We present the first observations of extragalactic pulsating stars in the K2 ecliptic survey of the Kepler space telescope. Variability of all three RR Lyrae stars in the dwarf spheroidal galaxy Leo IV were successfully detected, at a brightness of Kp~21.5 mag, from data collected during Campaign 1. We identified one modulated star and another likely Blazhko candidate with periods of 29.8+-0.9 d and more than 80 d, respectively. EPIC 210282473 represents the first star beyond the Magellanic Clouds for which the Blazhko period and cycle-to-cycle variations in the modulation were unambiguously measured.The photometric [Fe/H] indices of the stars agree with earlier results that Leo IV is a very metal-poor galaxy. Two out of three stars blend with brighter background galaxies in the K2 frames. We demonstrate that image subtraction can be reliably used to extract photometry from faint confused sources that will be crucial not only for the K2 mission but for future space photometric missions as well.
Mild and Efficient Synthesis of <i>N</i> <sup>1</sup>,<i>N</i> <sup>5</sup>,<i>N</i> <sup>10</sup>-Tri-<i>tert</i>-butoxycarbonyl Spermine (2011)

Abstract This article describes a mild and efficient synthesis of N1 ,N5 ,N10 -tri-tert-butoxycarbonyl spermine from putrescine, with a 41% overall yield. The key steps include a Michael addition and Raney nickel (W-2) reduction. The advantages of this synthesis include a simple procedure, mild conditions, and good yields.
Measurement and Estimation of Large Loudspeaker Array Performance (1990)

While the individual elements used in large loudspeaker arrays may be well documented, the performance characteristics of the complete arrays themselves have not generally been measured in detail. Measurements on limited arrays, in conjunction with array theory and advanced modeling techniques, correlate well with observations made of large arrays and thus from the basis for accurate estimation of the performance of arbitrary arrays in large spaces
Particle Size Distribution Inferred from Small-Angle X-ray Scattering and Transmission Electron Microscopy (1998)

Particle size distributions determined by small-angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) are investigated for samples of interacting hard spheres. Polydispersity in the samples is determined from the SAXS data by fitting the Porod region to the form factor of a sphere of uniform electron density smeared by a Gaussian distribution of sphere diameters. We find good agreement between SAXS-determined particle size distributions and those calculated from TEM image analysis.
The effect of the bridge group on the thermal stability of nitro‐substituted aromatic polyamides (1993)

Abstract The effect of introducing a bridge group into the diamine moiety on the thermal stability of aromatic polyamides substituted with nitro group in the diamine ring at the ortho position to the amide group was studied. Our present work showed that the bridge group, whether it was electron withdrawing or releasing, did not have a significant effect on the activity of the nitro group for the intramolecular cyclization reaction to poly(benzoxazole)s.
Effects of a Competitive Inhibitor (Mevinolin) of 3‐Hydroxy‐3‐methylglutaryl Coenzyme A Reductase on Human and Bovine Endothelial Cells, Fibroblasts and Smooth Muscle Cells <i>in Vitro</i> (1989)

Mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity, is a potent inhibitor of cholesterol synthesis. We have tested the effects of mevinolin on cell replication (3H-thymidine incorporation), prostacyclin production (6-keto-PGF1 alpha) and cell death (51Cr release) in cell cultures (human umbilical vein endothelial cells, bovine endothelial cells, human fibroblasts and bovine smooth muscle cells). Mevinolin concentrations ranging from 0.05 mumol/l (reported therapeutic concentration) to 20 mumol/l were used. In human endothelial cells the replication was reduced by 11% at a concentration of 2.0 mumol/l (P less than 0.01). In fibroblasts and smooth muscle cells the reduction was significant already at 0.1 mumol/l (10%, P less than 0.01). The prostacyclin production was reduced in endothelial cells at 1.0 mumol/l (19%, P less than 0.01) and in smooth muscle cells at 2.0 mumol/l (15%, P less than 0.05). At 20 mumol/l both cell replication and prostacyclin production was markedly reduced by about 40% in all cell types. No effects on 51Cr release or trypan blue staining was seen at any concentration. It is concluded that mevinolin has an effect on DNA synthesis and prostacyclin production on the tested cell types in vitro. These effects were, however, observed only at concentrations higher than those recommended for therapeutical use.
Effect of Hygroscopic Swelling of Mold Compound on PEM Reliability (2003)

Polymeric mold compounds absorb moisture, and thus swell, when exposed to a humid environment [1]. Hygroscopic stresses arise in plastic encapsulated microcircuits (PEMs) when the mold compound swells upon absorbing moisture and the lead frame, die paddle, and semiconductor chip, do not experience swelling.
Relationship between endogenous 3-methylhistidine excretion and body composition (1981)

Fourteen healthy men (aged 20-30 yr) consumed two isocaloric, isonitrogenous diets in the sequence of a 4-day meat diet (MD) followed by a 7-day meal-free diet (MFD). Urinary 3-methylhistidine (3MH) excretion during the MD (513 +/- 21 mumol . day-1, mean +/- SE) was significantly higher (P less than 0.01) than day 3 of the MFD (230 +/- 10 mumol . day-1), after which the mean daily 3MH output was constant with a mean coefficient of variation of 4.5%. There was no change in fat-free body mass (FFBM) determined by densitometry at the start (62.3 +/- 1.8 kg) and the end (62.2 +/- 1.9 kg) of the 11-day dietary period. Mean muscle mass (MM) calculated from measurements of total-body potassium and nitrogen was 23.4 +/- 1.3 kg. Endogenous 3MH excretion was related more closely to MM (r = 0.91, P less than 0.001) than to FFBM measured by densitometry (r = 0.81, P less than 0.001). Only a low correlation coefficient (r = 0.33, P less than 0.05) was observed between 3MH and the nonmuscle component of FFBM. Urinary creatinine output also was correlated significantly with 3MH (r = 0.87; P less than 0.001) and MM (r = 0.79; P less than 0.01). It is concluded that because endogenous 3MH is significantly related to MM in man, it can be used as a marker to study in vivo total-body muscle protein degradation provided that the necessary dietary restrictions are observed.
Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: A randomized clinical trial (2017)

FMT from a rationally selected donor reduced hospitalizations, improved cognition, and dysbiosis in cirrhosis with recurrent HE. (Hepatology 2017;66:1727-1738).
Potential Role of mTORC2 as a Therapeutic Target in Clear Cell Carcinoma of the Ovary (2013)

The goal of this study was to examine the role of mTOR complex 2 (mTORC2) as a therapeutic target in ovarian clear cell carcinoma (CCC), which is regarded as an aggressive, chemoresistant histologic subtype. Using tissue microarrays of 98 primary ovarian cancers [52 CCCs and 46 serous adenocarcinomas (SAC)], activation of mTORC2 was assessed by immunohistochemistry. Then, the growth-inhibitory effect of mTORC2-targeting therapy, as well as the role of mTORC2 signaling as a mechanism for acquired resistance to the mTOR complex 1 (mTORC1) inhibitor RAD001 in ovarian CCC, were examined using two pairs of RAD001-sensitive parental (RMG2 and HAC2) and RAD001-resistant CCC cell lines (RMG2-RR and HAC2-RR). mTORC2 was more frequently activated in CCCs than in SACs (71.2% vs. 45.7%). Simultaneous inhibition of mTORC1 and mTORC2 by AZD8055 markedly inhibited the proliferation of both RAD001-sensitive and -resistant cells in vitro. Treatment with RAD001 induced mTORC2-mediated AKT activation in RAD001-sensitive CCC cells. Moreover, increased activation of mTORC2-AKT signaling was observed in RAD001-resistant CCC cells compared with the respective parental cells. Inhibition of mTORC2 during RAD001 treatment enhanced the antitumor effect of RAD001 and prevented CCC cells from acquiring resistance to RAD001. In conclusion, mTORC2 is frequently activated, and can be a promising therapeutic target, in ovarian CCCs. Moreover, mTORC2-targeted therapy may be efficacious in a first-line setting as well as for second-line treatment of recurrent disease developing after RAD001-treatment.
Most “Dark Matter” Transcripts Are Associated With Known Genes (2010)

A series of reports over the last few years have indicated that a much larger portion of the mammalian genome is transcribed than can be accounted for by currently annotated genes, but the quantity and nature of these additional transcripts remains unclear. Here, we have used data from single-and paired-end RNA-Seq and tiling arrays to assess the quantity and composition of transcripts in PolyA+ RNA from human and mouse tissues. Relative to tiling arrays, RNA-Seq identifies many fewer transcribed regions (''seqfrags'') outside known exons and ncRNAs. Most nonexonic seqfrags are in introns, raising the possibility that they are fragments of pre-mRNAs. The chromosomal locations of the majority of intergenic seqfrags in RNA-Seq data are near known genes, consistent with alternative cleavage and polyadenylation site usage, promoter-and terminator-associated transcripts, or new alternative exons; indeed, reads that bridge splice sites identified 4,544 new exons, affecting 3,554 genes. Most of the remaining seqfrags correspond to either single reads that display characteristics of random sampling from a low-level background or several thousand small transcripts (median length = 111 bp) present at higher levels, which also tend to display sequence conservation and originate from regions with open chromatin. We conclude that, while there are bona fide new intergenic transcripts, their number and abundance is generally low in comparison to known exons, and the genome is not as pervasively transcribed as previously reported.
Continuous restricted Boltzmann machine with an implementable training algorithm (2003)

The authors introduce a continuous stochastic generative model that can model continuous data, with a simple and reliable training algorithm. The architecture is a continuous restricted Boltzmann machine, with one step of Gibbs sampling, to minimise contrastive divergence, replacing a time-consuming relaxation search. With a small approximation, the training algorithm requires only addition and multiplication and is thus computationally inexpensive in both software and hardware. The capabilities of the model are demonstrated and explored with both artificial and real data.
Security, Performance, and Applications of Smart Contracts: A Systematic Survey (2019)

Blockchain is the promising technology of recent years, which has attracted remarkable attention in both academic studies and practical industrial applications. The smart contract is a programmable transaction that can perform a sophisticated task, execute automatically, and store on the blockchain. The smart contract is the key component of the blockchain, which has made blockchain a technology beyond the scope of the cryptocurrencies and applicable for a variety of applications such as healthcare, IoT, supply chain, digital identity, business process management, and more. Although in recent years the progress toward improving blockchain technology with the focus on the smart contract has been impressive, there is a lack of reviewing the smart contract topic. This paper systematically reviews the key concepts and proposes the direction of recent studies and developments regarding the smart contract. The research studies are presented in three main categories: 1) security methods and tools; 2) performance improvement approaches; and 3) decentralized applications based on smart contracts.
Misalignment angles’ reduction in Bi2212 multifilaments melted by dynamic heat treatment under a magnetic field (2007)

International audience
Information Flow Certification Using an Intermediate Code Program Representation (1981)

This paper describes a compile-time information flow control (IFC) mechanism that certifies secure information flow within the collection of objects accessed by a program. The IFC mechanism is based on the lattice model and certification mechanism of Denning, who proposes the use of the mechanism during the analysis phase of compilation. However, IFC is placed after semantic analysis and before code optimization by ufilizing an intermediate code representation. This reduces the complexity of IFC and allows a degree of language independence. An implentation has been developed for Pascal.
Bundle min-hashing for logo recognition (2013)

We present a scalable logo recognition technique based on feature bundling. Individual local features are aggregated with features from their spatial neighborhood into bundles. These bundles carry more information about the image content than single visual words. The recognition of logos in novel images is then performed by querying a database of reference images.
Entanglement of Two Impurities through Electron Scattering (2006)

We study how two magnetic impurities embedded in a solid can be entangled by an injected electron scattering between them and by subsequent measurement of the electron's state. We start by investigating an ideal case where only the electronic spin interacts successively through the same unitary operation with the spins of the two impurities. We find conditions for the impurity spins to be maximally entangled with a significant success probability. We then consider a more realistic description which includes both the forward and backscattering amplitudes. In this scenario, we obtain the entanglement between the impurities as a function of the interaction strength of the electron-impurity coupling. We find that our scheme allows us to entangle the impurities maximally with a significant probability.
Mumps epidemic in Portugal despite high vaccine coverage - preliminary report (1996)

A measles, mumps, and rubella (MMR) trivalent vaccine was added to Portugal's National Immunisation Programme (NIP) in 1987. All vaccines are given at health centres, free of charge, but an epidemic of mumps began in 1995, firstly in northern Portugal and
Of anthropoids and instructional designers (2005)

This study has its origins in an environment producing interactive educational multimedia materials for adults. It begins at an intersection where a particular device of interface is being developed under the influence of an educational designer. It intends travelling from there, with the aid of a generally qualitative compass, toward a goal of creating a coherent descriptive framework. Built primarily on selected cases and perspectives from designers who have employed the device in these, the study is initiated with an intention of creating three products: A rationale for use of static visual humanoid devices; A scheme to describe the placement of such visuals in the interface and their pedagogical or other roles, and; A map of design decision processes and the attributes among which designers choose in arriving at a particular visual manifestation, providing an indication of factors affecting choices made.
THE WONDERS OF THE WORLD AND OF THE <i>THREE KINGDOMS OF NATURE</i> Pages 1-316 (2010)

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Structure and Function of the Nuclear Pore Complex (1992)

Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary ...Read More