gebhart/patrepeval huggingface dataset:
Context-aware privacy protection with profile management (2006)

Hotspot services will be offered in small, highly-populated public places like airports, hospitals, etc. They will play their assistive roles in the people's life only if they are secure, trusted, and nonobtrusive. Some of the challenges faced are the seamless operation between WLAN-based hotspots and other emerging wireless data networks technologies, for example body sensor networks; the exploitation of context- and location-aware information provided from the hotspot service; matching the user needs with differentiated services; preserving the privacy of the user's sensitive data and anonymity. To answer these challenges, a new solution for context-aware privacy protection for any type of fine-grained user sensitive data with profiles of the user, context, scenario and service is proposed. Based on assessment of current context and situation, the user delegates actions for protecting his privacy to the proposed mechanism that acts on his behalf. The discussed solution is presented with a medical scenario. Components model, interaction sequence, algorithm for privacy safeguarding and system implementation are described.
Power-aware scheduling for periodic real-time tasks (2004)

We address power-aware scheduling of periodic tasks to reduce CPU energy consumption in hard real-time systems through dynamic voltage scaling. Our intertask voltage scheduling solution includes three components: 1) a static (offline) solution to compute the optimal speed, assuming worst-case workload for each arrival, 2) an online speed reduction mechanism to reclaim energy by adapting to the actual workload, and 3) an online, adaptive and speculative speed adjustment mechanism to anticipate early completions of future executions by using the average-case workload information. All these solutions still guarantee that all deadlines are met. Our simulation results show that our reclaiming algorithm alone outperforms other recently proposed intertask voltage scheduling schemes. Our speculative techniques are shown to provide additional gains, approaching the theoretical lower-bound by a margin of 10 percent.
A Fast Method to Mine Frequent Subsequences from Graph Sequence Data (2008)

In recent years, the mining of a complete set of frequent subgraphs from labeled graph data has been extensively studied.However, to our best knowledge, almost no methods have been proposed to find frequent subsequences of graphs from a set of graph sequences. In this paper, we define a novel class of graph subsequences by introducing axiomatic rules of graph transformation, their admissibility constraints and a union graph. Then we propose an efficient approach named "GTRACE'' to enumerate frequent transformation subsequences (FTSs) of graphs from a given set of graph sequences. Its fundamental performance has been evaluated by using artificial datasets, and its practicality has been confirmed through the experiments using real world datasets.
Cauliflower mosaic virus as a gene expression vector for plants (1990)

It is possible to replace the CaMV (cauliflower mosaic virus) ORF (open reading frame) II with foreign sequences without interfering with virus viability. Such recom‐binants can induce the synthesis of substantial amounts of a foreign protein in infected plants and confer new properties to these plants. However, so far only three genes have been successfully cloned and expressed in this way. The expression mechanism of CaMV demands precise replacement of ORF II and probably certain structural features of the viral 35S RNA, which should not be disturbed by inserted sequences. Since these features are largely unknown, it cannot at present be pre‐dicted whether an insert will be tolerated. It is more likely that larger inserts will disturb the viral gene expression mechanism than smaller ones.
Hollow waveguides with low intrinsic photoluminescence fabricated with Ta2O5 and SiO2 films (2011)

A type of integrated hollow core waveguide with low intrinsic photoluminescence fabricated with Ta(2)O(5) and SiO(2) films is demonstrated. Hollow core waveguides made with a combination of plasma-enhanced chemical vapor deposition SiO(2) and sputtered Ta(2)O(5) provide a nearly optimal structure for optofluidic biofluorescence measurements with low optical loss, high fabrication yield, and low background photoluminescence. Compared to earlier structures made using Si(3)N(4), the photoluminescence background of Ta(2)O(5) based hollow core waveguides is decreased by a factor of 10 and the signal-to-noise ratio for fluorescent nanobead detection is improved by a factor of 12.
Comparative Study of Pore Size of Low-Dielectric-Constant Porous Spin-on-Glass Films Using Different Methods of Nondestructive Instrumentation (2001)

The pore sizes of hydrogen-methyl-siloxane-based porous spin-on-glass (SOG) thin films having different k values ( k =1.8–2.5) are comparatively studied using different nondestructive instrumental ways and also with reference to sorption porosimetry. The pore size and its spread are found to increase with increasing porosity, or with decreasing dielectric constant.
The stages of type 1A diabetes: 2005 (2005)

Type 1A diabetes is a chronic autoimmune disease usually preceded by a long prodrome during which autoantibodies to islet autoantigens are present. These antibodies are directed to a variety of antigens, but the best characterized are glutamic acid decarboxylase-65, insulinoma-associated antigen-2, and insulin. We hypothesize that the natural history of type 1A diabetes can be represented by several stages, starting from genetic susceptibility and ending in complete beta-cell destruction and overt diabetes. Type 1A diabetes probably results from a balance between genetic susceptibility and environmental influences. In both humans and animal models, the major determinants of the disease are genes within the major histocompatibility complex. The next best-characterized susceptibility locus is the insulin gene, the variable nucleotide tandem repeat locus. This gene affects the expression of insulin in the thymus and thus may play a role in the modulation of tolerance to this molecule. In a subset of genetically susceptible individuals, the activation of autoimmunity may be triggered by environmental factors such as viruses and/or diet. However, no conclusive association has been established between type 1A diabetes and specific environmental triggers. In this review, we provide evidence that insulin has a fundamental role in anti-islet autoimmunity.
Investigation of acute ocular injury threshold by 76 GHz band exposure in rabbits (2011)

The acute ocular injury threshold of 76 GHz band millimeter wave (MMW) exposure was investigated using an in vivo rabbit model. Pigmented rabbits were exposed unilaterally to 200, 100, 75, 50, 10 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> 76 GHz band MMW for 6 min with a lens antenna. Corneal opacity, epithelial injury, miosis, and ocular inflammation were present up to 2-3 days after exposure at a dose of 200 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . No ocular changes other than reversible corneal epithelial injury were seen following exposure at 100 and 75 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . There were no ocular changes after exposure at doses of 50 or 10 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . Six-minute exposure to 76 GHz 10 mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> did not induce any detectable ocular tissue damage.
Relation between natriuresis and urinary excretion of hydrogen peroxide (1999)

Changes in the urinary hydrogen peroxide by exercise or salt load were studied in six healthy male volunteers. Exercise was performed by bicycle ergometer for 30 min at the intensity of 80% of the maximum heart rate predicted by age. Urinary excretion rate of hydrogen peroxide showed a tendency to increase in the salt load experiment, and to decrease by exercise. Correlation coefficient between urinary excretion rate of sodium and hydrogen peroxide one hour after the load was 0.797 (0.1 > p > 0.05) in the exercise experiment, 0.892 (p <0.05) in the salt load experiment and 0.877 (p < 0.001) in both experiments. Correlation coefficient between area under the curve for sodium excretion and hydrogen peroxide excretion was also as high as 0.822 (p < 0.05) in the exercise experiment, 0.909 (p < 0.05) in the salt load experiment and 0.853 (p < 0.001) in both experiments. These results may suggest that urinary excretion rate of hydrogen peroxide is closely related to metabolism of electrolytes and fluid in the renal tubules.
High-brightness, AlGaInP-based, visible light-emitting diode for efficient coupling with POF (1995)

A high-brightness light-emitting diode (LED) is fabricated using the AlGaInP based quaternary double heterostructure. The ring type electrode is used in the top contact in order to spread the current efficiently and also to enhance the coupling efficiency with the fiber. The fabricated LED has a light output as high as 1.7 mW at the bias current of 100 mA. The far-field radiation divergences are found to be approximately 100 and 70/spl deg/ for the LED's, with and without molding. These LED's offer coupling efficiency as high as 70% and 35%, with the step index (SI) plastic optical fiber (POF) after using the molded and hybrid ball lens, respectively. The increases of the coupling efficiency are due to the use of the ring-shaped top electrode, concentrating the emission mostly at the center.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Grape Remote Sensing Atmospheric Profile and Evapotranspiration Experiment (2018)

Abstract Particularly in light of California’s recent multiyear drought, there is a critical need for accurate and timely evapotranspiration (ET) and crop stress information to ensure long-term sustainability of high-value crops. Providing this information requires the development of tools applicable across the continuum from subfield scales to improve water management within individual fields up to watershed and regional scales to assess water resources at county and state levels. High-value perennial crops (vineyards and orchards) are major water users, and growers will need better tools to improve water-use efficiency to remain economically viable and sustainable during periods of prolonged drought. To develop these tools, government, university, and industry partners are evaluating a multiscale remote sensing–based modeling system for application over vineyards. During the 2013–17 growing seasons, the Grape Remote Sensing Atmospheric Profile and Evapotranspiration eXperiment (GRAPEX) project has collected micrometeorological and biophysical data within adjacent pinot noir vineyards in the Central Valley of California. Additionally, each year ground, airborne, and satellite remote sensing data were collected during intensive observation periods (IOPs) representing different vine phenological stages. An overview of the measurements and some initial results regarding the impact of vine canopy architecture on modeling ET and plant stress are presented here. Refinements to the ET modeling system based on GRAPEX are being implemented initially at the field scale for validation and then will be integrated into the regional modeling toolkit for large area assessment.
Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant (2015)

ERBB2 is an oncogenic receptor tyrosine kinase overexpressed in a subset of human breast cancer and other cancers. We recently found that human prolidase (PEPD), a dipeptidase, is a high affinity ERBB2 ligand and cross-links two ERBB2 monomers. Here, we show that recombinant human PEPD (rhPEPD) strongly inhibits ERBB2-overexpressing tumors in mice, whereas it does not impact tumors without ERBB2 overexpression. rhPEPD causes ERBB2 depletion, disrupts oncogenic signaling orchestrated by ERBB2 homodimers and heterodimers, and induces apoptosis. The impact of enzymatically-inactive mutant rhPEPD<sup>G278D</sup> on ERBB2 is indistinguishable from that of rhPEPD, but rhPEPD<sup>G278D</sup> is superior to rhPEPD for tumor inhibition. The enzymatic function of rhPEPD stimulates HIF-1α and other pro-survival factors in tumors, which likely attenuates its antitumor activity. rhPEPD<sup>G278D</sup> is also attractive in that it may not interfere with the physiologic function of endogenous PEPD in normal cells. Collectively, we have identified a human protein as an inhibitory ERBB2 ligand that inhibits ERBB2-overexpressing tumors <i>in vivo</i>. Several anti-ERBB2 agents are on the market but are hampered by drug resistance and high drug cost. rhPEPD<sup>G278D</sup> may synergize with these agents and may also be highly cost-effective, since it targets ERBB2 with a different mechanism and can be produced in bacteria.
Differentiation from the Family of Origin and Adjustment to College in Young Adults (1995)

This study investigated the relation between second-semester freshmen's and first-semester sophomores' views of the perceived psychological health of their family of origin and their adjustment to college. A significant relation was found between social and personal adjustment to college and the perceived psychological health of the family of origin. The findings suggest that students having problems with social and personal adjustment to college might benefit more from family counseling than from individual counseling.
Bicarbonate modulation of glucose-9nduced biphasic insulin release by rat islets (1976)

The role of HCO3 ions in pancreatic beta-cell functions was evaluated with isolated rat islets. The early phase of insulin release was absent when HCO3 ions were omitted from the medium prior to glucose stimuation, but was augmented if HCO3- withdrawal or reintroduction coincided with glucose increase. The inhibition of the late phase augmented as a function of the duration of HCO3- absence, and its reversibility upon readmission of the anion was delayed. Theophylline and cytochalasin B partially corrected the inhibition of the late phase but failed to restore a rapid response. In the presence of 5 mM NaHCO3, the early response was delayed but the total response was normal. In a HCO3--free medium, glucose oxidation and utilization and glucose transport in islet cells were unaltered. Uptake of calcium was reduced in the absence of HCO3 ions, but normal in 5 mM HCO3-. The results document the importance of HCO3- in insulin release and show that the two phases of glucose-induced secretion are differentially modified by its omission. Some of these findings may be explained by alterations in Ca++ uptake by islet cells. It is suggested that the mechanisms regulating insulin granule extrusion upon stimulation by glucose may be partially different for the two phases of release.
A COMPLEMENT FIXATION TEST FOR POLIOMYELITIS (1955)

A macroscopic (tube) complement fixation test for poliomyelitis, using infected tissue culture fluids, is described. The test was applied to 27 individuals with a clinical diagnosis of poliomyelitis. In 18 patients it was possible to make a laboratory diagnosis of poliomyelitis on the basis of a rise in complement-fixing antibody titer and in 4 others on the basis of a high stationary antibody titer. One individual gave a high and equal antibody response to two virus types, 3 others had no detectable antibody, and 1 appeared not to have poliomyelitis. Heterotypic reactions were encountered, but gave little difficulty in interpreting homologous responses. In those patients from whom a virus had been recovered, the serologic findings corresponded to the virus type recovered. The possible occurrence of dual infections with the viruses of poliomyelitis and Western equine and St. Louis encephalitis is discussed.
Tool-supported single authoring for device independence and multimodality (2005)

With the growing proliferation of mobile computing devices, the vision of the web anytime, anywhere and on any device is rapidly becoming a reality. Technologies enabling device-independent presentation and new interaction modalities like voice or gesture are moving from research to commercially available products. As a result, developers are faced with the increasing challenge of providing user interfaces that match the capabilities of the different devices available. Within this paper we present our application-oriented research that has investigated single authoring of multimodal interfaces on mobile devices. After an overview of related work that explains the motivation behind our approach, we present a prototype authoring tool for the development of graphical as well as multimodal web-based user interfaces for multiple devices. We conclude by discussing the relation of our work to established web markup standards and point out noteworthy issues related to their application within our work.
Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice (2014)

Pharmacological inhibition of the VLA-4/vascular adhesion molecule-1 axis in experimental stroke was ineffective in our hands. Our results cast doubt on the effectiveness of anti-CD49d as a stroke treatment. Further translational studies should be performed before testing anti-VLA-4 antibodies in patients with stroke.
The Ralstonia eutropha H16 phasin PhaP1 is targeted to intracellular triacylglycerol inclusions in Rhodococcus opacus PD630 and Mycobacterium smegmatis mc2155, and provides an anchor to target other proteins (2006)

In Ralstonia eutropha , the H16 phasin PhaP1 represents the major phasin that binds to the surface of polyhydroxyalkanoate (PHA) inclusions. In this study, C-terminal fusions of PhaP1 with enhanced green fluorescent protein (eGFP) and with Escherichia coli β -galactosidase (LacZ) were expressed separately in the triacylglycerol (TAG)-accumulating actinomycetes Rhodococcus opacus PD630 and Mycobacterium smegmatis mc 2 155, employing the M. smegmatis acetamidase ( ace ) promoter of the Escherichia–Mycobacterium / Rhodococcus shuttle plasmid pJAM2. PhaP1 and the PhaP1 fusion proteins were expressed stably in the recombinant strains. Western blot analysis of cell fractions of Rh. opacus revealed that PhaP1 and the PhaP1–eGFP fusion protein were associated with the TAG inclusions, whereas no phasin or phasin fusion protein was detected in the soluble and membrane fractions. Additional electron microscopy/immunocytochemistry studies demonstrated that PhaP1 was mainly located on the surface of intracellular TAG inclusions; in addition, some PhaP1 also occurred at the plasma membrane. Fluorescence microscopic investigations of the subcellular distribution of the PhaP1–eGFP fusion protein in vivo and on isolated TAG inclusions revealed that the fusion protein was bound to TAG inclusions at all stages of their formation, and to some extent at the cytoplasmic membrane. The PhaP1–LacZ fusion protein also bound to the TAG inclusions, and could be separated together with the inclusions from Rh. opacus crude extracts, thus demonstrating the immobilization of β -galactosidase activity on the inclusions. This is believed to be the first report demonstrating the ability of PhaP1 to bind to lipid inclusions in addition to PHA inclusions. Furthermore, it was demonstrated that this non-specificity of PhaP1 can be utilized to anchor enzymically active fusion proteins to a matrix of bacterial TAG inclusions.
An analysis of a new access control technique for channel request in wireless communications (2002)

Medium access control protocols are at the core of many wireless communication systems with shared channel resources. Recent proposed MAC protocols tend to divide bandwidth into 2 parts. The first part is used to contend among all users for channel reservation and the second part used for actual data transmission for users who succeed in reservation. From the significant role of the first part, the access probability used by all users for determining whether or not to access the request slot for channel reservation, is an important factor effecting on the system performance. Therefore, this paper presents a full analysis for deriving a new optimal access technique that an optimal access probability used in the system is selected in accordance with the present system condition taking the number of users and number of request slots into consideration. The results from our analysis show that in the system which each user has only a single access per frame the new technique outperforms all conventional techniques in all tested traffic and system environments.
A Systematic Evaluation of the Immunomodulatory and Functional Properties of Probiotic Bifidobacterium breve BR03 (DSM 16604) Lactobacillus plantarum LP01 (LMG P-21021) (2019)

The human intestinal microbiota may be considered as a post-natally acquired organ composed of a large diversity of bacteria with different functions on human health. Probiotics are widely used to improve gut functionality and immune system responses. The aim of this study was to evaluate the capability of the bacterial strains Bifidobacterium breve BR03 (DSM 16604) and Lactobacillus plantarum LP01 (LMG P-21021) to induce an in vitro immune response in the peripheral blood mononuclear cells (PBMCs) of healthy adult volunteers and to modify the state of oxidative stress and intestinal permeability of in vitro cell models. Specifically, the analysis was conducted on PBMCs after different stimulation times in order to analyze both cells involved in innate immunity and those responsible for acquired immunity and to evaluate the oxidative stress, and on Caco-2 cell line as an intestinal epithelium model.
Routine neonatal circumcision: the gap between contemporary policy and practice. (1982)

Attitudes, knowledge, and personal factors related to circumcision in the newborn period were analyzed among a group of 92 randomly selected primary care physicians and 103 parents of male infants. Sixty-five percent of the physicians conveyed a positive attitude about routine neonatal circumcision to their patients; pediatricians were more likely to have a neutral attitude, and both family and general practitioners were more likely to encourage routine neonatal circumcision (P less than .01). Routine neonatal circumcision was favored more often by older, male, and circumcised physicians. Knowledge about the normal anatomy of the infants' foreskin was inadequate. Parents rarely perceived physicians as influential in the decision-making process (P less than .001). In contrast, fathers' circumcision status and parental belief in medical indications were positively related to the decision to circumcise (P less than .001 and P less than .01, respectively). The data suggest directions for change in clinical pediatric practice that may bring contemporary policy with regard to routine neonatal circumcision closer to actual practice.