gebhart/patrepeval huggingface dataset:
A Framework For Personalizable Community Web Portals (2001)

In this paper we present a framework for the creation of community web portals. The framework provides the necessary infrastructure for the management of several portlets, which divide the available space for information display on the portal page. The management infrastructure includes authentication, layout and user profile services. The framework also provides a portlet infrastructure for displaying and filtering information from heterogeneous information sources of structured information. This infrastructure is based on a layered approach which keeps the source integration, filtering and presentation layers quasi-independent. Available filter templates can be freely assigned to any information source with any display template for display in a portlet. We achieve this layer independence by using a standard set of information fields for internal processing. The heterogeneous information sources are then mapped to this standard field set. 1.
Thyroglobulin antibody (TgAb) methods – Strengths, pitfalls and clinical utility for monitoring TgAb-positive patients with differentiated thyroid cancer (2013)

Thyroglobulin autoantibodies (TgAb) are detected at diagnosis or during treatment in approximately 25% of patients with differentiated thyroid cancer (DTC). When present, TgAb interferes with thyroglobulin (Tg) measurement causing falsely low or undetectable Tg immunometric assay (IMA) values that can mask disease. Guidelines mandate that every Tg test have TgAb measured simultaneously and quantitatively by immunoassay and not a recovery test. The propensity and magnitude of TgAb-Tg interference relates to both Tg and TgAb concentrations and the class of Tg method used. Because the TgAb trend reflects changes in thyroid tissue mass, TgAb concentrations serve as a surrogate post-operative DTC tumor marker. A rising, or de novo appearance of TgAb may indicate recurrence, whereas a progressive decline suggests successful treatment. This review focuses on the technical limitations of current TgAb methods, characteristics of TgAb interference with different classes of Tg method, and the clinical value of monitoring TgAb trends as a surrogate DTC tumor marker.
Cell Size Control (2006)

Abstract Growth in biological systems is defined as the accumulation of mass, which leads to an increase in size. In this article, we discuss how cells, organs, and organisms normally control growth, and how deregulated growth can lead to a variety of pathological conditions.
Embracing Open Source Multimedia Software (2012)

Acknowledging the relevance of developments in the open source software community, the ACM International Conference on Multimedia (or ACM MM) has held its Open Source Software Competition every year since 2004. This competition has steadily grown since its inception, from two finalist entries in 2004 to 14 in 2011. This article reports on the Open Source Competition at ACM MM 2011 and the conference's associated panel discussion. To help communicate their intention and impact, videos of the winning project (OpenIMAJ and ImageTerrier) and the two honorable mentions (ClassX and OpenCast) are included here as Web extras. Video 1: "ClassX" by Sherif A. Halawa, Bernd Girod, and Derek Pang (Stanford University). Video 2: "OpenIMAJ/ImageTerrier" by Jonathon Hare, Sina Samangooei, and David Dupplaw (University of Southampton, UK). Video 3: "OpenCast" by Michelle Ziegmann (University of California at Berkeley) and Olaf A. Schulte (ETH Zurich).
Selenium and Inflammation— Potential Use and Future Perspectives (2015)

The essential trace element selenium (Se) is constitutively incorporated as selenocysteine, in proteins, among others in antioxidative selenoproteins, such as glutathione peroxidase(s) and thioredoxin reductase. Since chronic inflammation is thought to deplete Se stores in the body, Se supplementation should be considered in prolonged inflammatory states, Se being the trace element the most affected in chronic or low-grade inflammation. Se administration might also be beneficial in bacterial and viral diseases as well as metabolic and autoimmune diseases. In order to maintain a Se steady state, or “selenostasis,” Se supplementation, via either diet or compounds, is required to preserve the activity of selenoproteins in antioxidative and redox processes. Importantly, Se could play a pivotal role in the maintenance of homeostasis in infected tissues by inhibiting the proinflammatory toll-like receptor nuclear factor kappa-light-chain-enhancer of activated B cells signaling pathway and counteracting proinflammatory cytokine action. Finally, while Se status shows considerable promise as a valid marker of inflammatory and autoimmune disease, new functional Se nanoparticles and highly bioavailable selenomethionine compounds will in all probability provide a more efficacious and reliable intervention tool in both preventive and therapeutic disease management.
Supervised reconstruction of biological networks with local models (2007)

An implementation of the proposed algorithm is available upon request from the authors.
ABOUT DIFFERENTIAL DIAGNOSTICS OF HORMONAL OSTEOPATHIES (1968)

As you know, most of the endocrine diseases are accompanied by some or other changes in the osteoarticular system, which are often based on osteoporosis.
Cellular fluorescent high-throughput screening assays of the ATP-gated P2X7 receptor (2013)

The P2X7 receptor (P2X7R) is an important member of the P2X family of ligand-gated ion channels that respond to ATP as the endogenous agonist. Studies suggest that P2X7R plays a potentially pivotal role in a variety of physiological functions, including peripheral and central neuronal transmission, smooth muscle contraction, and inflammation. Thus, P2X7R may be a potential target for drug development. Here, we used a FlexStation to examine the function of recombinant P2X7R stably expressed in human embryonic kidney 293 cells and to compare three high-throughput screening assays: a membrane potential assay, an ethidium bromide uptake assay, and a calcium influx assay. We found that all three assays were suitable for the analysis of P2X7R, but the calcium influx assay was the most robust and is the best choice as a first high-throughput screening assay when embarking on a P2X7R drug discovery project.
Osteopontin and Interleukin-8 Expression is Independently Associated with Prostate Cancer Recurrence (2008)

In prostatectomy specimens, osteopontin expression is independently associated with biochemical recurrence. Both osteopontin and IL-8 may be predictors of early disease progression.
Experimental blasting in the Cananea Open Pit Mine (1972)

This item was digitized from a paper original and/or a microfilm copy. If you need higher-resolution images for any content in this item, please contact us at repository@u.library.arizona.edu.
Bilateral Renal Hypoplasia With Oligomeganephronia (1970)

The syndrome of congenital bilateral renal hypoplasia with hypertrophy of nephrons has been well documented in the French literature, but has attracted little attention in North America. We have described two patients with clinical and histological features of the disease. The clinical picture is one of progressive chronic renal failure with symptoms of vomiting, fever, and dehydration occurring in early infancy. The essential pathologic features are a reduction in the size of both kidneys, and a decrease in the number but a marked increase in size of the remaining glomeruli. The possible causes of glomerular hypertrophy are briefly discussed.
Synthesis and <i>in Vitro</i> Characterization of Antigen-Conjugated Polysaccharide as a CpG DNA Carrier (2006)

Oligodeoxynucleotides containing unmethylated CpG sequences (CpG DNAs) are known as an immune adjuvant. CpG DNAs coupled with a particular antigen enabling both CpG DNA and antigen delivery to the same antigen-presenting cell have been shown to be more effective. Based on our previous finding that beta-(1-->3)-D-glucan schizophyllan (SPG) can be used as a CpG DNA carrier, here we present the synthesis of an antigen-conjugated SPG and the characterization of the conjugate. Ovalbumin (OVA, 43 kDa) was used as a model antigen, and two OVA were conjugated to one SPG molecule (M(w) = 150,000), denoted by OVA-SPG. Circular dichroism and gel electrophoresis showed that OVA-SPG could form a complex with a (dA)(40)-tailed CpG DNA at the 3' end (1,668-(dA)(40)). When OVA-SPG was added to macrophages (J774.A1), the amount of the ingested OVA-SPG was increased compared with that of OVA itself, suggesting that Dectin-1 (proinflammatory nonopsonic receptor for beta-glucans) is involved to ingest OVA-SPG. Furthermore, the complex of the conjugate and DNA was co-localized in the same vesicles, implying that OVA (antigen) and CpG DNA (adjuvant) were ingested into the cell at the same time. This paper shows that OVA-SPG can be used as a CpG DNA carrier to induce antigen-specific immune responses.
Basic Fibroblast Growth Factor Impregnated Hydrogel Microspheres for Embolization of Cerebral Arteriovenous Malformations (1998)

To assess the prevention of recanalization at embolized sites in cerebral arteriovenous malformations, the authors devised a novel embolic material, hydrogel microspheres prepared from poly(ethylene glycol) diacrylate impregnated with basic fibroblast growth factor. In this article, preparation of the microspheres, and preliminary study of in vitro and in vivo performance are discussed. Poly(ethylene glycol) diacrylate, prepared from end capping of poly(ethylene glycol) (molecular weights, 1,000, 2,000, and 4,000) with acryloyl chloride and benzophenone derived poly(ethylene glycol), prepared from poly(ethylene glycol) (molecular weight, 2,000) with benzoyl benzoic acid chloride as a photoinitiator, were dissolved in a buffer solution with or without basic fibroblast growth factor. The mixed solution was dropped stepwise into liquid paraffin with stirring. Ultraviolet light irradiation resulted in the formation of relatively rigid hydrogel microspheres (diameter, 100-400 microm). The in vitro study showed that the higher the molecular weight of poly(ethylene glycol) diacrylate used, the faster the release rate of immobilized protein. Canine kidneys were embolized with these microspheres via the femoral artery using a microcatheter. Histologic examination showed that microspheres occluded arterioles. The degree of accumulation of fibroblasts and extracellular matrix were larger for basic fibroblast growth factor impregnated microspheres than for nonimpregnated ones. Basic fibroblast growth factor released from microspheres may help regenerate tissues at arteriovenous malformation sites, and recanalization is expected to be prevented.
Delayed wound healing in mice associated with viral alteration of macrophages. (1983)

Mice acutely and chronically infected with Sendai virus had impaired healing of incisional wounds. This impairment could be overcome by instilling the macrophage-stimulators zymosan and glucan into full-thickness incised wounds, whereas levamisole, an immunomodulator, had no effect on tensile strength of these wounds (breaking strengths). Another commonly occurring murine virus, murine hepatitis virus, also reduced wound tensile strength in infected mice. However, the murine strain of herpes simplex virus, type 1, which caused greater morbidity, did not reduce tensile strength. Although measurements of wound length and wound breaking strength clearly showed the adverse effect of viral infection, histologic evaluation of wounds did not consistently reveal a similar change in composition of wound "cell aggregation centers" for mice infected with the Sendai and murine hepatitis viruses.
Selective catalytic reduction of sulfur dioxide by carbon monoxide over iron oxide supported on activated carbon (2014)

The selective reduction of sulfur dioxide with carbon monoxide to elemental sulfur was studied over AC-supported transition-metal oxide catalysts. According to the study, Fe_2O_3/AC was the most active catalyst among the 4 AC-supported catalysts tested. By using Fe_2O_3/AC, the best catalyst, when the feed conditions were properly optimized (CO/SO_2 molar ratio = 2:1; sulfidation temperature, 400 °C; Fe content, 20 wt%; GHSV = 7000 mL g^{-1} h^{-1}), 95.43% sulfur dioxide conversion and 86.59% sulfur yield were obtained at the temperature of 350 °C. Catalyst samples were characterized by X-ray powder diffraction in order to relate the phase composition to the activation behavior and catalytic performance. The active phase of catalyst was detected as FeS_2, and the formation of FeS_2 was greatly dependent on the sulfidation temperature.
Transposition of gentamicin resistance to staphylococcal plasmids encoding resistance to cationic agents (1984)

Plasmid pWG115 isolated from a methicillin-resistant Staphylococcus aureus encodes resistance to cationic surface-active agents and trimethoprim. It has a molecular weight of ca 14.6 megadaltons and can be transferred to other strains of staphylococci in mixed-culture transfer with propamidine isethionate as a selective agent. Gentamicin resistance in Australian methicillin-resistant Staph. aureus isolates can be either chromosomal or plasmid-borne. The most common gentamicin resistance plasmid is 18.0 megadaltons and also encodes resistance to trimethoprim and cationic surface-active agents. This suggested that pWG115 was related to gentamicin resistance plasmids and that it may provide a target for the postulated gentamicin resistance transposon. This paper demonstrates that the chromosomal gentamicin resistance determinant from WG523 can transpose into pWG115 to generate an 18.0 megadalton plasmid, phenotypically indistinguishable from the naturally occurring gentamicin resistance plasmids such as pWG53. EcoR1 restriction enzyme analysis demonstrated that gentamicin resistance can transpose into at least two sites on pWG115. One of these sites generates EcoR1 restriction fragments identical to pWG53. The 5.2 kilobase pair (3.4 megadalton) element involved confers low-level resistance to gentamicin, cross resistance to tobramycin and kanamycin, and has been designated Tn3851.
Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent (2016)

The Signal Transducer and Activator of Transcription 3 (STAT3) oncogene is a master regulator of many human cancers, and a well-recognized target for therapeutic intervention. A well known STAT3 inhibitor, S3I-201 (NSC 74859), is hypothesized to block STAT3 function in cancer cells by binding the STAT3 SH2 domain and disrupt STAT3 protein complexation events. In this study, liquid chromatography tandem mass spectrometry analysis revealed that STAT3, in the presence of S3I-201, showed a minimum of five specific sites of modification, cysteine's 108, 259, 367, 542, and 687. Moreover, a prepared fluorescently labeled chemical probe of S3I-201 (DB-6-055) revealed that S3I-201 non-specifically and globally alkylated intracellular proteins at concentrations consistent with S3I-201's reported IC50. These data are consistent with the hypothesis that S3I-201 is a sub-optimal probe for interrogating STAT3-related cell biology.
Pseudo-Outbreak of<i>Pseudomonas aeruginosa</i>and<i>Serratia marcescens</i>Related to Bronchoscopes (2003)

Prevention of pseudo-outbreaks requires meticulous use of preventive measures for infection-prone medical procedures.
Inhibition of Glutamine Synthetase and Quantitative Changes of Free Amino Acids in Shoots of Bialaphostreated Japanese Barnyard Millet (1986)

食用ビエ茎葉部から抽出したグルタミン合成酵素 (GS) に対して, ビアラホスは0.3～3mMの範囲では阻害作用を示さなかったが, インタクトの植物に散布処理した場合, 顕著なGS活性の阻害が認められた. 一方, ビアラホスの代謝物のL-AMPBはそれらの両方でGS活性を阻害した. したがってビアラホスは植物体内で代謝され, L-AMPBになってGSを阻害したと考えられる. ビアラホスを散布処理した食用ビエ茎葉の遊離アミノ酸量を測定したところ, 15種中12種で増加が認められた. 一方, 処理後24～48時間でグルタミンの顕著な減少が認められた. グルタミンの減少が殺草作用の原因であることが考えられたので, ビアラホスをグルタミンとともに散布処理したところ, ビアラホス単独に比べて体内グルタミン量は増加したが, 殺草作用の強さは変化しなかった. したがって, グルタミンの減少は殺草作用の第一義的な要因ではないと考えられる.
El capital riesgo y los Business Angels (2001)

Los nuevos proyectos empresariales precisan de formas adecuadas de financiacion ademas de las formas tradicionales de obtencion de recursos. El capital riesgo y los business angels constituyen apoyos a tener en cuenta en el arranque de las nuevas inciativas empresariales. Estos ultimos son objeto de analisis en este articulo en el que, ademas de revisar algunas experiencias concretas, se dibujan las condiciones para un rapido desarrollo de una fuente de recursos vital para le aumento del ritmo de natalidad y crecimiento posterior de empresas.
Low impedance gate drive for full control of voltage controlled power devices (2014)

In order to have full control of voltage controlled, power devices gate voltages must be under control. This requires low impedance (R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</sub> and L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</sub> ) in gate drive circuits. A prototype of a gate drive circuits applied to an IGBT half-bridge module, results in L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</sub> of 2.5nH and gate resistance R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</sub> of 0.54 Ohm for a 400A/1200V IGBT module. Test results demonstrate the controllability of the gate voltage during switching, as well as during short circuit conditions. Due to improved control of gate voltage, short circuit current becomes lower by 30%. In order to allow low impedance in the gate drive circuit, switching slopes are adjusted by shaping the input signals to the gate drivers.
Fiber Bragg grating sensing system for simultaneous measurement of salinity and temperature (2004)

A fiber optic sensing system for simultaneous measurement of temperature and salinity based on fiber Bragg grating technology is presented. The fabrication process, which relies on chemical etching of the fibre, is described and its performance is evaluated. Theoretical and experimental results are given, which are summarized on the obtained resolutions of 60.06°C/AHz and 60.2‰/ AHz for temperature and salin- ity, respectively. © 2004 Society of Photo-Optical Instrumentation Engineers.
Toxic shock syndrome-associated staphylococcal and streptococcal pyrogenic toxins are potent inducers of tumor necrosis factor production (1989)

Toxic shock syndrome-associated staphylococcal and streptococcal exotoxins were tested for an ability to induce the production of tumor necrosis factor (TNF). Staphylococcal enterotoxins B and C1, along with streptococcal pyrogenic exotoxin A, all induced TNF production in a dose-dependent manner, with production peaking on the average at 3 days but continuing over the 6 days tested. This time course of exotoxin-induced TNF production contrasts with the 1-day peak-2-day duration observed with endotoxin as the stimulus and may be significant to development of toxic shock syndrome.
Designing a Low-Cost Ceramic Water Filter Press (2013)

Diarrheal disease due to unsanitary water is a leading cause of death in low- and middle- income countries. One potential solution to this problem is widespread access to point-of-use ceramic water filters made from universally-available materials. This increased access can be achieved by empowering local artisans to initiate self-sustaining and scalable entrepreneurial ventures in their communities. However, a major barrier to the start-up of these businesses is the prohibitively expensive press used to form the filters. This article reviews filter press technologies and identifies specific functional requirements for a more suitable and affordable filter press. Early-stage field-testing results of a proof-of-concept design that can be manufactured by two people in two days at one-tenth of the cost of popular filter presses is presented.
Gaining Hands-On Experience with Solid-State Photovoltaics through Constructing a Novel n-Si/CuS Solar Cell (2017)

A solid-state p–n junction photovoltaic cell can be fabricated in a common chemistry lab. It is prepared by coating a p-type copper sulfide film on an n-type silicon wafer via a simple chemical bath deposition method. The resulting p–n junction shows an obvious photovoltaic effect. This activity offers students an opportunity to gain hands-on experience with the technology of solid-state solar cells.
Unsupervised Learning from Video to Detect Foreground Objects in Single Images (2017)

Unsupervised learning from visual data is one of the most difficult challenges in computer vision. It is essential for understanding how visual recognition works. Learning from unsupervised input has an immense practical value, as huge quantities of unlabeled videos can be collected at low cost. Here we address the task of unsupervised learning to detect and segment foreground objects in single images. We achieve our goal by training a student pathway, consisting of a deep neural network that learns to predict, from a single input image, the output of a teacher pathway that performs unsupervised object discovery in video. Our approach is different from the published methods that perform unsupervised discovery in videos or in collections of images at test time. We move the unsupervised discovery phase during the training stage, while at test time we apply the standard feed-forward processing along the student pathway. This has a dual benefit: firstly, it allows, in principle, unlimited generalization possibilities during training, while remaining fast at testing. Secondly, the student not only becomes able to detect in single images significantly better than its unsupervised video discovery teacher, but it also achieves state of the art results on two current benchmarks, YouTube Objects and Object Discovery datasets. At test time, our system is two orders of magnitude faster than other previous methods.
Structures and energies of the lithiated silanes (1989)

Preliminary ab initio calculations for the entire series of lithiated silanes SiH4 –nLin are reported. Tetrahedral and planar structures of these species are fully optimized and the resulting tetrahedral–planar energy differences are estimated and compared with those of the lithiated methanes. Basis set effects on the calculated structures of lithiated silanes are discussed. In addition performance of the semiempirical MNDO method in the case of the silicon–lithium systems considered is assessed.
Photoinduced Charge Transfer and Electrochemical Properties of Triphenylamine <i>I</i><sub><i>h</i></sub>-Sc<sub>3</sub>N@C<sub>80</sub> Donor−Acceptor Conjugates (2009)

Two isomeric [5,6]-pyrrolidine-I(h)-Sc(3)N@C(80) electron donor-acceptor conjugates containing triphenylamine (TPA) as the donor system were synthesized. Electrochemical and photophysical studies of the novel conjugates were made and compared with those of their C(60) analogues, in order to determine (i) the effect of the linkage position (N-substituted versus 2-substituted pyrrolidine) of the donor system in the formation of photoinduced charge separated states, (ii) the thermal stability toward the retro-cycloaddition reaction, and (iii) the effect of changing C(60) for I(h)-Sc(3)N@C(80) as the electron acceptor. It was found that when the donor is connected to the pyrrolidine nitrogen atom, the resulting dyad produces a significantly longer lived radical pair than the corresponding 2-substituted isomer for both the C(60) and I(h)-Sc(3)N@C(80) dyads. In addition to that, the N-substituted TPA-I(h)-Sc(3)N@C(80) dyad has much better thermal stability than the 2-substituted one. Finally, the I(h)-Sc(3)N@C(80) dyads have considerably longer lived charge separated states than their C(60) analogues, thus approving the advantage of using I(h)-Sc(3)N@C(80) instead of C(60) as the acceptor for the construction of fullerene based donor-acceptor conjugates. These findings are important for the design and future application of I(h)-Sc(3)N@C(80) dyads as materials for the construction of plastic organic solar cells.