gebhart/patrepeval huggingface dataset:
Transvenous Management of Pulmonary Embolic Disease (1974)

Clinical pulmonary embolic disease was categorized into four classes according to hemodynamic and respiratory effects of the occlusion at the time of diagnosis. A new approach to management of massive embolization (Class III and IV) by transvenous catheter embolectomy was attempted in ten patients with initial success in eight. Three additional deaths occurred postoperatively, two from recurrent embolization prior to vena caval plication. In view of this preventable complication, a wire filter device was developed for insertion at the time of embolectomy. The filter has also been utilized in 15 additional patients with lesser degrees of embolization (Class II). The conal shape of the device permits preservation of flow after embolic capture and followup venacavagrams in nine patients up to 20 months postoperative shows patency in all. Complications occurred in both groups related both to the underlying disorder and to the catheter technics.
Purification and characterization of a novel protease from culture filtrates of a<i>Streptomyces</i>sp. (1996)

A fibrinolytic protease has been isolated from Streptomyces sp. culture filtrate by successive chromatography on Mono S and Sephadex G50. The purified protease had a molecular mass of 33 kDa and had an isoelectric point of 6.7. It showed a sharp pH optimum at 7.8 with maximal protease activity between 35 degrees C and 50 degrees C. Its amino acid composition and amino-terminal sequence (17 residues) were determined. The protein exhibited marked hydrolytic activity toward the substrates N-Succ-(Ala)2-Pro-Phe-pNA (K(m) = 0.77 mM, Vmax = 24.2 mumol mg-1 min-1) and N-Succ-(Ala)2-Pro-Leu-pNA (K(m) = 0.92 mM, Vmax = 7.7 mumol mg-1 min-1). It was totally inhibited by alpha 1-antitrypsin, D-Phe-Pro-Arg-chloromethylketone and sodium dodecyl sulfate but was insensitive to EDTA, dithiothreitol, phenylmethylsulfonyl fluoride, soybean trypsin inhibitor, pepstatin or elastatinal. In this respect, this protease differed in its physico-chemical and biochemical properties from other extracellular proteases previously found in bacteria and fungi. The results suggest that it has properties of chymotrypsin-like serine-type proteases.
Hybrid Deformable Models for Medical Segmentation and Registration (2006)

Deformable models have had great successes over the past 20 years in medical applications. We have recently developed new classes of deformable models which we term hybrid deformable models to automate the model initialization process and make improvements in segmentation and registration. In this paper we present several hybrid deformable methods we have been developing for segmentation and registration. These methods include metamorphs, a novel shape and texture integration deformable model framework and the integration of deformable models with graphical models and learning methods. We first present a framework for the robust segmentation and tracking of the heart from tagged MRI images and second applications involving brain tumor segmentation as well as brain and cardiac shape registration
Sputtered thin film piezoelectric aluminium nitride as a functional MEMS material and CMOS compatible process integration (2011)

A comprehensive study on the complete process module for the fabrication of AlN-based MEMS sensors and actuators is presented. The investigations include the influence of the electrode material, AlN thickness and stress tuning during sputtering on the material parameters, especially the piezoelectric coefficients. It is shown that AlN layers deposited at only 200 °C have good piezoelectric properties. The tuning of residual layer stress has little influence on the piezoelectric properties of AlN. Further two methods of wet chemical etching of AlN are compared. The complete CMOS compatible processing of AlN-based MEMS structures is demonstrated on 200 mm wafers.
Structural and magnetic properties of core shell iron iron oxide nanoparticles (2002)

We present studies of the structural and magnetic properties of core–shell iron–iron oxide nanoparticles. α-Fe nanoparticles were fabricated by sputtering and subsequently covered with a protective nanocrystalline oxide shell consisting of either maghaemite (γ-Fe2O3) or partially oxidized magnetite (Fe3O4). We observed that the nanoparticles were stable against further oxidation, and Mössbauer spectroscopy at high applied magnetic fields and low temperatures revealed a stable form of partly oxidized magnetite. The nanocrystalline structure of the oxide shell results in strong canting of the spin structure in the oxide shell, which thereby modifies the magnetic properties of the core–shell nanoparticles.
ChemInform Abstract: Study of Cu2+ Location in Zeolites Na‐A and K‐A by ESR and ESE Spectroscopies. (1987)

Abstract The determination of the Cu 2+ location in hydrated and dehydrated Cu2+‐doped Na‐A and K‐A zeolites is achieved by partial exchange of the zeolites by Cs + cations, which occupy well‐defined crystallographic sites, and monitoring the weak hyperfine interaction between Cu 2+ and Cs+.
Anisotropic properties of Na-β″-alumina + YSZ composite synthesized by vapor phase method (2017)

Abstract
Perceptual evaluation of speech quality-implementation using a non-traditional symbian operating system (2009)

The ever increasing challenges to provide high quality, reliable and low cost mobile voice services have made speech quality a major area of research. Due to evolving and liberalized market, the quality of telecommunication voice services has become an important issue. With the advent of new technologies, however, a diversification takes place which makes it necessary to carefully plan and observe network quality. A characteristic of the competitive telecommunications market is the convergence in many aspects of service, such as price between different operators. In this environment, speech quality is becoming a key factor distinguishing one operator from another - a strong indicator for customer satisfaction. Therefore, it is imperative that a service provider is capable of predicting customers' perceptions of quality so that networks can be optimized and maintained.
Implementation and performance evaluation of the LRFU replacement policy (2002)

Recently, a new block replacement policy called the LRFU (Least Recently/Frequently Used) policy was proposed that subsumes both the LRU and LFU policies, and provides a spectrum of replacement policies between them. We describe an implementation of the LRFU replacement policy in the FreeBSD 2.1.5 and present a performance evaluation of the implementation using the SPEC SDET benchmark. The results show that the new policy gives up to a 30% performance improvement over the LRU block replacement policy.
A novel method for improving the fault tolerance of transformerless cascade PWM STATCOM (2008)

A novel control method is presented for improving the reliability of transformerless cascade STATCOMs operating under various faults. A modified H bridge circuit is proposed, and it could be totally bypassed under various faults while the STATCOM keep working. During the fault transient, by controlling the phase of a STATCOMpsilas output voltage, the DC capacitors could be charged or discharged to maintain the STATCOMpsilas capability of outputting reactive power. The simulation results about the performances of the proposed method and circuit are given.
Successive cancellation list polar decoder using log-likelihood ratios (2014)

Successive cancellation list (SCL) decoding algorithm is a powerful method that can help polar codes achieve excellent error-correcting performance. However, the current SCL algorithm and decoders are based on likelihood or log-likelihood forms, which render high hardware complexity. In this paper, we propose a log-likelihood-ratio (LLR)-based SCL (LLR-SCL) decoding algorithm, which only needs half the computation and storage complexity than the conventional one. Then, based on the proposed algorithm, we develop low-complexity VLSI architectures for LLR-SCL decoders. Analysis results show that the proposed LLR-SCL decoder achieves 50% reduction in hardware and 98% improvement in hardware efficiency.
Characteristics of scintillators for well logging to 225 degrees C (1990)

Application-oriented performance characteristics for scintillators (NaI(Tl), CsI(Tl), CsI(Na), BGO, and BC-438 plastic) were evaluated as a function of temperature from 25 degrees C to 225 degrees C, as appropriate. Relative pulse height and pulse height resolution are reported. It is shown that the scintillator most appropriate for measurement above 100 degrees C is NaI(Tl). At 200 degrees C, NaI(Tl) still has more than 50% of its light output and its pulse height resolution has increased by less than a factor of 1.5. Because the decay constants of scintillators tend to shorten, shorter integration time constants can be used at higher temperatures to collect all the charge generated by the photomultiplier tube. Differences in the data due to geometry suggest that volume absorption effects are present and that these effects have a stronger temperature dependence than the scintillator itself.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Using cache to reduce power in content-addressable memories (CAMs) (2006)

We propose using caching to save power in content-addressable memories (CAMs). By using a small cache along with the CAM, we avoid accessing the larger and higher power CAM. For a cache hit rate of 90%, the cache-CAM (C-CAM) saves 80% power over a conventional CAM, for a cost of 15% increase in silicon area. Even at a low hit rate of 50%, a power savings of 40% is achieved. The proposed C-CAM is employed in the design of a testchip demonstrating a 2.6 fJ/bit/search in a 0.18 mum CMOS process
PDA: Progressive Data Augmentation for General Robustness of Deep Neural Networks (2019)

Adversarial images are designed to mislead deep neural networks (DNNs), attracting great attention in recent years. Although several defense strategies achieved encouraging robustness against adversarial samples, most of them fail to improve the robustness on common corruptions such as noise, blur, and weather/digital effects (e.g. frost, pixelate). To address this problem, we propose a simple yet effective method, named Progressive Data Augmentation (PDA), which enables general robustness of DNNs by progressively injecting diverse adversarial noises during training. In other words, DNNs trained with PDA are able to obtain more robustness against both adversarial attacks as well as common corruptions than the recent state-of-the-art methods. We also find that PDA is more efficient than prior arts and able to prevent accuracy drop on clean samples without being attacked. Furthermore, we theoretically show that PDA can control the perturbation bound and guarantee better generalization ability than existing work. Extensive experiments on many benchmarks such as CIFAR-10, SVHN, and ImageNet demonstrate that PDA significantly outperforms its counterparts in various experimental setups.
A Cockcroft-Walton for FELTRON: the new mu -wave source for TeV colliders (1992)

A pulsed powerful Cockcroft-Walton generator for an electrostatic accelerator is presented. The electrostatic accelerator is designed to provide a pulsed electron beam of 5.5 MeV, 100 A, and 0.5 mu s with a repetition rate of 1 kHz. The output voltage has a descending staircase waveform. This voltage provides an electron beam made up of ten sections having different energies. Two adjacent pieces have a relative energy variation Delta gamma ij/ gamma of 1%. A dispersive system spatially separates those sections into ten 50-ns-long electron beam pulses.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
RNA Extraction by the Proteinase K Method (2003)

This method of RNA extraction relies on a relatively gentle lysis procedure that should burst the cells, but leave the nuclei intact. Contamination of a relatively RNase-free cytoplasmic environment with nuclear nucleases is thus minimised. Next the polysomes are dissociated with SDS and proteinase K and finally the protein is removed by several phenol/choloroform extractions (1,2).
Cryotherapy modifies synthetic activity and differentiation of keloidal fibroblasts <i>in vitro</i> (2003)

In order to obtain a persuasive explanation for the beneficial clinical effect of cryotherapy on keloids, we developed a reproducible model to apply freezing temperatures on cell cultures, and investigated their influence on proliferation, viability, synthetic activity and differentiation of dermal fibroblasts in vitro. Cell cultures were established from 13 untreated keloids and 10 healthy skin specimens matched for age and skin localization to the donors. No significant influence of cell freezing on the proliferation rates of both keloidal and normal fibroblasts was documented, but mechanical cell destruction with a wide variation in lethality rates (29% average lethal effect on keloidal fibroblasts and 41% on normal ones) was observed. When comparing specimens of keloidal and normal tissue derived from the same four donors, the keloidal fibroblasts were similar regarding their synthetic activity but presented enhanced tenascin-C expression compared with the normal fibroblasts. After cryotherapy, delayed collagen III increase was detected in both cell types (P = 0.03). The collagen II/collagen I ratio increased from 1.6 to 2.8 in the keloidal and only from 1.9 to 2.2 in the normal fibroblasts after subcultivation. Normal fibroblasts exhibited a significantly lasting increase in fibronectin synthesis after freezing (P = 0.03). The intensity of staining against tenascin-C was decreased in five of nine keloidal fibroblast cultures after cryotherapy (P < 0.05) but increased in four of five normal fibroblast cultures (P = 0.016), so that the intensity of tenascin-C staining after freezing became identical in both cell types. Immunoblot studies in four patients and two controls confirmed a temporary decrease of tenascin-C in keloidal but not in normal fibroblasts immediately after freezing. Significantly decreased staining with two markers of myogenic differentiation, myosin in keloidal fibroblasts (P = 0.002) and desmin (P = 0.007) in normal fibroblasts, could also be detected after treatment. In summary, with the help of a model for controlled cell freezing in vitro, cryotherapy was found to modify collagen synthesis and differentiation of keloidal fibroblasts.
Direct Interaction between Protein Kinase Cθ (PKCθ) and 14-3-3τ in T Cells: 14-3-3 Overexpression Results in Inhibition of PKCθ Translocation and Function† (1996)

Recent studies have documented direct interactions between 14-3-3 proteins and several oncogene and proto-oncogene products involved in signal transduction pathways. Studies on the effects of 14-3-3 proteins on protein kinase C (PKC) activity in vitro have reported conflicting results, and previous attempts to demonstrate a direct association between PKC and 14-3-3 were unsuccessful. Here, we examined potential physical and functional interactions between PKC theta, a Ca(2+)-independent PKC enzyme which is expressed selectively in T lymphocytes, and the 14-3-3 tau isoform in vitro and in intact T cells. PKC theta and 14-3-3 tau coimmunoprecipitated from Jurkat T cells, and recombinant 14-3-3 tau interacted directly with purified PKC theta in vitro. Transient overexpression of 14-3-3 tau suppressed stimulation of the interleukin 2 (IL-2) promoter mediated by cotransfected wild-type or constitutively active PKC theta, as well as by endogenous PKC in ionomycin- and/or phorbol ester-stimulated cells. This did not represent a general inhibition of activation events, since PKC-independent (but Ca(2+)-dependent) activation of an IL-4 promoter element was not inhibited by 14-3-3 tau under similar conditions. Overexpression of wild-type 14-3-3 tau also inhibited phorbol ester-induced PKC theta translocation from the cytosol to the membrane in Jurkat cells, while a membrane-targeted form of 14-3-3 tau caused increased localization of PKC theta in the particulate fraction in unstimulated cells. Membrane-targeted 14-3-3 tau was more effective than wild-type 14-3-3 tau in suppressing PKC theta-dependent IL-2 promoter activity, suggesting that 14-3-3 tau inhibits the function of PKC theta not only by preventing its translocation to the membrane but also by associating with it. The interaction between 14-3-3 and PKC theta may represent an important general mechanism for regulating PKC-dependent signals and, more specifically, PKC theta-mediated functions during T-cell activation.
<i>Lgr6</i> Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin (2010)

Mammalian epidermis consists of three self-renewing compartments: the hair follicle, the sebaceous gland, and the interfollicular epidermis. We generated knock-in alleles of murine Lgr6, a close relative of the Lgr5 stem cell gene. Lgr6 was expressed in the earliest embryonic hair placodes. In adult hair follicles, Lgr6+ cells resided in a previously uncharacterized region directly above the follicle bulge. They expressed none of the known bulge stem cell markers. Prenatal Lgr6+ cells established the hair follicle, sebaceous gland, and interfollicular epidermis. Postnatally, Lgr6+ cells generated sebaceous gland and interfollicular epidermis, whereas contribution to hair lineages gradually diminished with age. Adult Lgr6+ cells executed long-term wound repair, including the formation of new hair follicles. We conclude that Lgr6 marks the most primitive epidermal stem cell.
Environmentally Friendly Solvent‐Processed Organic Solar Cells that are Highly Efficient and Adaptable for the Blade‐Coating Method (2017)

The power conversion efficiencies (PCEs) of state-of-the-art organic solar cells (OSCs) have increased to over 13%. However, the most commonly used solvents for making the solutions of photoactive materials and the coating methods used in laboratories are not adaptable for future practical production. Therefore, taking a solution-coating method with environmentally friendly processing solvents into consideration is critical for the practical utilization of OSC technology. In this study, a highly efficient PBTA-TF:IT-M-based device processed with environmentally friendly solvents, tetrahydrofuran/isopropyl alcohol (THF/IPA) and o-xylene/1-phenylnaphthalene, is fabricated; a high PCE of 13.1% can be achieved by adopting the spin-coating method, which is the top result for OSCs. More importantly, a blade-coated non-fullerene OSC processed with THF/IPA is demonstrated for the first time to obtain a promising PCE of 11.7%; even for the THF/IPA-processed large-area device (1.0 cm<sup>2</sup> ) made by blade-coating, a PCE of 10.6% can still be maintained. These results are critical for the large-scale production of highly efficient OSCs in future studies.
Are Serine Proteases Involved in Immune Complex Activation of Neutrophils? (1988)

Soybean polypeptides and diisopropylfluorophosphate (DFP) have been reported to inhibit neutrophil functions such as the oxidative burst, chemotaxis, and/or phagocytosis in response to soluble stimuli; these observations would be compatible with the involvement of an active serine protease in neutrophil stimulation. We have investigated the possibility of such involvement when particulate stimuli such as immune complexes are utilized. The depolarization of the neutrophils' membrane potential, one of the earliest indicators of stimulation, and superoxide production, which is detectable 30-45 sec later, were our indicators of neutrophil response to immune complexes. The neutrophils were equilibrated with, and after 5 min washed free of, up to 60 mM DFP, a potent covalent serine protease inhibitor. At DFP concentrations below 24 mM, such treatment did not perturb neutrophil activation as measured by either of the above parameters, nor did F- alone under comparable conditions. Additionally, the immune complex induced responses of neutrophils preincubated for 3 min with N-alpha-p-tosyl-L-lysine chloromethylketone (TLCK), L-1-tosylamido-2-phenyl-ethyl-chloromethylketone (TPCK), or phenyl-methyl-sulfonyl-fluoride (PMSF), covalent serine protease inhibitors which have, however, been shown to function in other capacities, e.g., as superoxide dismutases; 1 mM PMSF or 0.5 mM TLCK consistently reduced the observed membrane depolarization, one of the earliest consequences of neutrophil activation, by 20-30%, while 0.1 mM TLCK and 0.01 mM TPCK had little or no effect. The inhibition of superoxide production, a slightly later stimulus response, by PMSF, TLCK, and TPCK was more profound (50-75%); these compounds have, however, been shown to have activities other than serine protease inhibitors--for example, as superoxide dismutases. Since DFP is purely a serine protease inhibitor, and since the three other compounds do not affect depolarization (the earlier and superoxide independent event), our results indicate that active serine proteases do not appear to be necessary for immune-complex-initiated neutrophil stimulation. Other stimuli, which are known to activate neutrophils by different pathways, were not investigated.
Overtone vibrations of OH groups in fused silica optical fibers (1981)

The OH-stretching fundamental, and the first, second, and third OH overtone vibrations have been examined using pure and GeO2 - doped graded index, fused silica optical fibers having OH contents from less than 1ppm to greater than 1,000 ppm. The previously reported component substructure of the fundamental vibrations of fused silica. Several new vibrations were uncovered and assigned. Examinations of deuterated OH samples helped to verify the assignments. The spectral broadening produced by GeO2 was interpreted in terms of a wider range of environments seen by the OH oscillators, compared to pure fused silica. (Author)
Alignment of University Information Technology Resources With the Malcolm Baldrige Results Criteria for Performance Excellence in Education: A Balanced Scorecard Approach (2014)

The authors suggest using a balanced scorecard (BSC) approach to evaluate information technology (IT) resources in higher education institutions. The BSC approach illustrated is based on the performance criteria of the Malcolm Baldrige National Quality Award in Education. This article suggests areas of potential impact of IT on BSC measures in each of the Baldrige Results Categories of the performance criteria. Many of the identified areas of measurement and expected improvement are unique to educational institutions. The multiple-faceted evaluation approach should provide improved assessment of an institution's IT resources and offer a broadened perspective of IT usage in the academic setting.
Chemical, In Vitro, and In Situ Evaluation of Heat-Treated Soybean Proteins (1991)

The effect on protein degradability of roasting soybeans and soybean meal and holding them at elevated temperatures for 0, .5, 1, 1.5, 2. 2.5, and 3 h was assessed using in vitro, in situ. and chemical techniques. Ruminal in vitro degradation rates decreased with initial roasting for both soybeans and soybean meal from .165 to .065 h-l and .155 to .092 h-l respectively. Roasting and holding for 3 h resulted in the lowest degradation rates.037 and .029 h-l for soybeans and soybean meal, respectively. In situ degradation rates decreased from .174 to .090 h-l and from .069 to .012 h-l , respectively, for soybeans and soybean meal roasted and held 3 h. There were no increases in ADIN with heat processing of soybeans. However. ADIN increased from 2.3 to 4.1 % When soybean meal was roasted and held 3 h. In contrast. nutritionally available lysine decreased dramatically during holding with a loss after 3 h of 22% for soybeans and 17% for soybean meal. Roasting and holding significantly increased estimated postmminally available lysine (g/kg DM) of soybeans from 6.5 to 10.5 (0 h) and 11.2 (mean, .5 to 3 h) and of soybean meal from 7.6 to 10.5 (0 h) and 14.2 (mean.5 to 3 h). Holding soybeans and soybean meal at an elevated temperature resulted in a more thorough and exten-