gebhart/patrepeval huggingface dataset:
Local optimization of global objectives: competitive distributed deadlock resolution and resource allocation (2002)

The work is motivated by deadlock resolution and resource allocation problems, occurring in distributed server-client architectures. We consider a very general setting which includes, as special cases, distributed bandwidth management in communication networks, as well as variations of classical problems in distributed computing and communication networking such as deadlock: resolution and "dining philosophers". In the current paper, we exhibit first local solutions with globally-optimum performance guarantees. An application of our method is distributed bandwidth management in communication networks. In this setting, deadlock resolution (and maximum fractional independent set) corresponds to admission control maximizing network throughput. Job scheduling (and minimum fractional coloring) corresponds to route selection that minimizes load.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Summary of ACM/ONR workshop on parallel and distributed debugging (1993)

article Free Access Share on Summary of ACM/ONR workshop on parallel and distributed debugging Editors: Barton P. Miller View Profile , Charles McDowell View Profile Authors Info & Claims ACM SIGOPS Operating Systems ReviewVolume 27Issue 4Oct. 1993 pp 8–23https://doi.org/10.1145/163640.163641Online:01 October 1993Publication History 1citation202DownloadsMetricsTotal Citations1Total Downloads202Last 12 Months7Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Generating service models by trace subsequence substitution (2013)

Software service emulation is an emerging technique for creating realistic executable models of server-side behaviour and is particularly useful in quality assurance: replicating production-like conditions for large-scale enterprise software systems. This allows performance engineers to mimic very large numbers of servers and/or provide a means of controlling dependencies on diverse third-party systems. Previous approaches to service emulation rely on manual definition of interaction behaviour requiring significant human effort. They also rely on either a system expert or documentation of system protocol and behaviour, neither of which are necessarily available. We present a novel method of automatically building client-server and server-server interaction models of complex software systems directly from interaction trace data, utilising longest common subsequence matching and field substitution algorithms. We evaluate our method against two common application-layer protocols: LDAP and SOAP. The results show that without explicit knowledge of the protocol specifications, our generated service models can produce well-formed responses for interactions. These responses can then be used within an emulation framework for large-scale enterprise system quality assurance purposes.
Microsoft Asp.Net with Microsoft Visual C# .Net Step by Step (2002)

Loss of function mutations in STAT3 (STAT3-LOF; autosomal dominant hyper-IgE (Job's) syndrome) are associated with a variety of musculoskeletal manifestations, including scoliosis, osteoporosis, and minimal trauma fractures. This retrospective magnetic resonance (MR) imaging study sought to characterize an unusual pattern of cervical spine degeneration among a cohort of STAT3-LOF patients. Cervical spine MR images of the STAT3-LOF cohort (n = 38) were assessed for a variety of degenerative changes and compared to age-matched groups of controls (n = 42) without known immune or musculoskeletal abnormalities. A unique pattern of premature cervical spine degeneration was identified among the STAT3-LOF cohort which included straightening and eventual reversal of the normal cervical lordosis, mainly due to multi-level spondylolisthesis, as well as early development of spinal canal narrowing, cord compression, and myelomalacia. Cervical spine degeneration in the STAT3-LOF cohort was significantly worse than controls in both the 30-45 and 45 + age groups. Moderate to severe degenerative changes were present after age 30, and markedly worsened over time in several cases. Bone mineral density (BMD) had a moderate negative correlation with cervical degeneration severity and a strong negative correlation with age among STAT3-LOF participants. Cervical degeneration in STAT3-LOF appears to be progressive and could result in cord compromise if left unaddressed. Focused history and physical examination for signs of neurologic compromise as well as periodic MR imaging are thus recommended for the evaluation of premature cervical spine degeneration in STAT3-LOF patients after age 30 so that timely surgical interventions may be considered to prevent spinal cord damage and permanent neurological deficits.
Optical hydrogen sensors based on metal-hydrides (2012)

For many hydrogen related applications it is preferred to use optical hydrogen sensors above electrical systems. Optical sensors reduce the risk of ignition by spark formation and are less sensitive to electrical interference. Currently palladium and palladium alloys are used for most hydrogen sensors since they are well known for their hydrogen dissociation and absorption properties at relatively low temperatures. The disadvantages of palladium in sensors are the low optical response upon hydrogen loading, the cross sensitivity for oxygen and carbon, the limited detection range and the formation of micro-cracks after some hydrogen absorption/desorption cycles. In contrast to Pd, we find that the use of magnesium or rear earth bases metal-hydrides in optical hydrogen sensors allow tuning of the detection levels over a broad pressure range, while maintaining a high optical response. We demonstrate a stable detection layer for detecting hydrogen below 10% of the lower explosion limit in an oxygen rich environment. This detection layer is deposited at the bare end of a glass fiber as a micro-mirror and is covered with a thin layer of palladium. The palladium layer promotes the hydrogen uptake at room temperature and acts as a hydrogen selective membrane. To protect the sensor for a long time in air a final layer of a hydrophobic fluorine based coating is applied. Such a sensor can be used for example as safety detector in automotive applications. We find that this type of fiber optic hydrogen sensor is also suitable for hydrogen detection in liquids. As example we demonstrate a sensor for detecting a broad range of concentrations in transformer oil. Such a sensor can signal a warning when sparks inside a high voltage power transformer decompose the transformer oil over a long period.
Neurologic and histopathologic evaluation after high-volume intrathecal amitriptyline (2004)

At lower doses, intrathecal injection of high volumes of amitriptyline results in long-acting spinal block. At higher doses, intrathecal amitriptyline results in irreversible neurologic deficit. Therefore, we do not recommend the use of intrathecal amitriptyline because of a very low therapeutic index.
Antioxidant behaviour of Ubiquinone and β-Carotene Incorporated in model Membranes (1986)

Experiments with model membranes, in which ubiquinone was incorporated, were performed in order to clarify the mechanism by which ubiquinone can prevent or control chain lipid peroxidation in biomembranes. Comparing the behavior of ubiquinone-containing vesicles with beta-carotene containing vesicles we suggest that a possible explanation of the ubiquinone antioxidant effect could be to scavenge singlet oxygen and to affect structurally the lipid bilayer inhibiting hydroperoxide decomposition.
Identification of Sexual Networks Through Molecular Typing of Quinolone-Resistant Neisseria gonorrhoeae in Ontario, Canada (2011)

Neisseria gonorrhoeae multi-antigen sequence typing technique demonstrated multiple sexual transmission networks in Ontario, Canada. Isolates with novel sequences had higher odds of originating in Toronto but had no association with heightened population-level quinolone exposure. Neisseria gonorrhoeae multi-antigen sequence typing technique can be a useful tool for investigation of multidrug-resistant N. gonorrhoeae emergence in North America.
Luis Maffei, Do Mundo de Herberto Helder, Rio de Janeiro, Oficina Raquel, 2017 (2018)

International audience
Cinematic “Assemblages”: The 1990s and Earlier (2010)

This book is an inquiry into the new Indian media world of the 1990s and the concomitant universe of commercial Hindi film. How did this period of titanic, techno-financial modernisation also witness paradoxically the rise of a ‘pre-modern’ ideology of Hindutva, hitherto languishing among the urban petit bourgeois and some agrarian-feudal quarters of north India? What is the assembling process in popular Hindi cinema, and what exactly happens when cinematic assembling becomes ‘informatic’ in a global sense? This book is not just an excursion into film and media theory, but also a political analysis of the globalisation of culture and urban life in a third world situation. It first examines the philosophy of the Indian cinematic assemblage and indicates how the assembling processes have always responded to ecological shifts in politics, media and fields of knowledge. First, it considers the realism debate and the definition of cinematic assemblage before discussing assemblages of totality and temporality as well as the thing-in-the-assemblage. It also looks at the body-in-the-assemblage, focusing on Dalit and the woman.
Direct nano-printing on Al substrate using a SiC mold (1998)

Nanostructures in Al were generated by printing with hard SiC molds. This nano-printing technology replaces the lithography and the etching or deposition processes to produce patterns directly in metal. Dots, short lines, and long lines were formed in the SiC molds by electron beam lithography and reactive ion etching. High aspect ratio features as small as 40 nm with depth up to 840 nm were patterned in the SiC molds. By pressing the SiC mold onto the Al substrate at room temperature, nanostructures in the SiC mold were reproduced accurately and uniformly in Al. Large arrays of nanostructures down to 40 nm were printed in Al with similar results for dots, short lines, and long lines. Using atomic force microscopy to analyze the cross sections of the SiC molds and printed Al nanostructures, depth dependence on feature size was observed. This nano-printing technology simplifies the processes for generating nanostructures with high throughput and high uniformity.
The Incidence and Prevalence of Neuromyelitis Optica (2013)

Interest in neuromyelitis optica (NMO) has increased substantially over the last few years, but it is not known whether NMO has the same geographic and temporal variations in disease risk as multiple sclerosis (MS). We aimed to evaluate the worldwide incidence and prevalence of NMO through a systematic review of published peer-reviewed studies. We performed a search of the English-language literature using MEDLINE and EMBASE from January 1985 to March 2012. Search terms included "neuromyelitis optica," "Devic's," "opticospinal," "incidence," "prevalence," and "epidemiology." We assessed study quality using a standardized instrument. A total of five studies met the inclusion criteria. Three of the studies were from North America, and all studies were published between 2005 and 2012. All studies were of good quality, but only one study reported standardized rates, and subgroup-specific estimates were rarely reported. The incidence of NMO per 100,000 population ranged from 0.053 to 0.40, while the prevalence per 100,000 population ranged from 0.52 to 4.4. Heterogeneity was high among the incidence (I(2) = 68.0%) and prevalence studies (I(2) = 94.0%). This review highlights the limited knowledge regarding the epidemiology of NMO and the importance of obtaining estimates standardized to common populations to enhance comparability of studies from different jurisdictions. Future studies would also benefit from reporting age-, sex-, and race- or ethnicity-specific estimates.
Intrinsic TGF-β signaling promotes age-dependent CD8+ T cell polyfunctionality attrition (2014)

Advanced age is associated with immune system deficits that result in an increased susceptibility to infectious diseases; however, specific mediators of age-dependent immune dysfunction have not been fully elucidated. Here we demonstrated that aged mice exhibit poor effector CD8+ T cell polyfunctionality, primarily due to CD8+ T cell-extrinsic deficits, and that reduced CD8+ T cell polyfunctionality correlates with increased susceptibility to pathogenic diseases. In aged animals challenged with the parasite Encephalitozoon cuniculi, effector CD8+ T cell survival and polyfunctionality were suppressed by highly elevated TGF-β1. Furthermore, TGF-β depletion reduced effector CD8+ T cell apoptosis in both young and aged mice and enhanced effector CD8+ T cell polyfunctionality in aged mice. Surprisingly, intrinsic blockade of TGF-β signaling in CD8+ T cells was sufficient to rescue polyfunctionality in aged animals. Together, these data demonstrate that low levels of TGF-β1 promote apoptosis of CD8+ effector T cells and high TGF-β1 levels associated with age result in both CD8+ T cell apoptosis and an altered transcriptional profile, which correlates with loss of polyfunctionality. Furthermore, elevated TGF-β levels are observed in the elderly human population and in aged Drosophila, suggesting that TGF-β represents an evolutionarily conserved negative regulator of the immune response in aging organisms.
Tyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins (2000)

The effects of Rho-specific modifying toxins on the tyrosine phosphorylation of endothelial cell proteins were investigated. Incubation of the cells with the Rho-activating toxin cytotoxic necrotizing factor 1 (CNF1) induced a marked increase in the tyrosine phosphorylation of a number of signalling intermediates of the vascular endothelial growth factor (VEGF)-mediated cascade, including focal adhesion kinase, paxillin, phospholipase Cγ1 and a Shc-associated protein of 195 kDa. Both CNF1- and VEGF-dependent tyrosine phosphorylation of these proteins were significantly reduced by prior incubation with C3 transferase, a known inhibitor of RhoA function, suggesting a Rho-dependent mechanism. The stimulation of endothelial cells with CNF1 resulted in a marked increase in the tyrosine phosphorylation of the VEGF receptor (VEGFR)-2, which was correlated with a stimulation of its kinase activity and with its association with downstream tyrosine phosphorylated proteins. The stimulatory effect of CNF1 was specific for VEGFR-2 since the phosphotyrosine content of VEGFR-1 was not affected by the toxin. Transient overexpression of a dominant-active RhoA mutant also induced an increase in the tyrosine phosphorylation of the VEGFR-2, whereas overexpression of a dominant-inactive form of the protein was without effect. Taken together, these results indicate that Rho proteins may play an important role in angiogenesis by modulating the tyrosine phosphorylation levels of VEGFR-2.
Using a GPU to Accelerate Die and Mold Fabrication (2007)

The authors present a GPU-based method for generating and verifying cutter paths for numerically controlled milling. A CAM system based on this technology is now employed in production at Mazda Motor Corporation for manufacturing stamping dies. This system can compute cutter paths more than 20 times faster than previous methods
InterPro and InterProScan (2007)

Protein sequence classification and comparison has become increasingly important in the current "omics" revolution, where scientists are working on functional genomics and proteomics technologies for large-scale protein function prediction. However, functional classification is also important for the bench scientist wanting to analyze single or small sets of proteins, or even a single genome. A number of tools are available for sequence classification, such as sequence similarity searches, motif- or pattern-finding software, and protein signatures for identifying protein families and domains. One such tool, InterPro, is a documentation resource that integrates the major players in the protein signature field to provide a valuable tool for annotation of proteins. Protein sequences are searched using the InterProScan software to identify signatures from the InterPro member databases; Pfam, PROSITE, PRINTS, ProDom, SMART, TIGRFAMs, PIRSF, SUPERFAMILY, Gene3D, and PANTHER. The InterPro database can be searched to retrieve precalculated matches for UniProtKB proteins, or to find additional information on protein families and domains. For completely sequenced genomes, the user can retrieve InterPro-based analyses on all nonredundant proteins in the proteome, and can execute user-selected proteome comparisons. This chapter will describe how to use InterPro and InterProScan for protein sequence classification and comparative proteomics.
Testing, Testing: Dialogue (2016)

Testing, Testing is an exhibition, book, symposium and second book by PhD practice-based researchers in fine art. The project seeks to explore the range of making practices that form part of artistic research methodologies, and to try and demonstrate how simple making process can advance an enquiry into art at PhD level. 

Experiments commonly form part of the artistic process but the title of this project speaks of the difficulties involved in inhabiting artistic research methodologies. How do researchers manage the uncertainties involved in experimental artistic production? Is artwork that is produced as research any different to artwork that is not? What makes art-as-research different to non-research-oriented art?

Wesseling (2011) suggests that the difference between an artist and an artist-researcher is the latter’s willingness to place their practice under scrutiny and open it up for public discussion. The exhibition and symposium were a way of opening up the processes, practices and approaches of each of the participating researchers to a public and entering into dialogue about them. Each of the artists in the exhibition and symposium did this in a different way. Some preferred a ‘crit group’ format, some presented rehearsed readings, and others offered more traditional conference presentations and discussions.
While each researcher tackled the project in ways that supported their own practices, and learned something about their particular approach, some general insights also emerged. The relevance of exhibition as a method of generating insight was underlined by the developmental processes some artist-researcher went through on the way to staging the work. Other artists found it beneficial and challenging to develop a piece of academic writing that came before the work and again after the work. The dual position of artist-research as both author and viewer of the work was occupied and developed throughout the project.

Reference
Wesseling, J. (2011). Introduction. In: See It Again, Say It Again: The Artist as Researcher. Antennae. Amsterdam: Valiz.
An objective long-term evaluation of the Angelchik antireflux prosthesis. (1991)

This paper reports the long-term results of the Angelchik antireflux prosthesis (ACP) in Nottingham from October 1981 to December 1989 in 42 patients with gastrooesophageal reflux disease (GORD). Pre- and postoperative oesophagoscopy, pH monitoring, acid reflux provocation test (ARPT), manometry and symptom evaluation were documented to assess the benefits of the procedure. There were no operative complications, dysphagia was the commonest postoperative problem and necessitated the removal of four ACPs. In most patients, dysphagia resolved within 1 year of surgery. Recurrence of reflux symptoms resulted in revision surgery in two patients. In general, reflux control was good. We believe that the ACP is a good antireflux operation which gives good long-term reflux and symptom control in the majority of patients. The removal rate of 15% in our series is of some concern but may be due in part to operator skills. The long-term objective follow-up has shown a trend towards a return of GOR and this and the unknown long-term effects of implanted silicone may limit the use of this procedure to the more elderly patient.
3D Micro‐ and Nanostructures via Interference Lithography (2007)

Abstract Interference lithography (IL) holds the promise of fabricating large‐area, defect‐free 3D structures on the submicrometer scale both rapidly and cheaply. A stationary spatial variation of intensity is created by the interference of two or more beams of light. The pattern that emerges out of the intensity distribution is transferred to a light sensitive medium, such as a photoresist, and after development yields a 3D bicontinuous photoresist/air structure. Importantly, by a proper choice of beam parameters one can control the geometrical elements and volume fraction of the structures. This article provides an overview of the fabrication of 3D structures via IL (e.g., the formation of interference patterns, their dependence on beam parameters and several requirements for the photoresist) and highlights some of our recent efforts in the applications of these 3D structures in photonic crystals, phononic crystals and as microframes, and for the synthesis of highly non spherical polymer particles. Our discussion concludes with perspectives on the future directions in which this technique could be pursued.
The future of cancer screening after COVID‐19 may be at home (2020)

During the coronavirus disease 2019 (COVID-19) pandemic, cancer screening decreased precipitously; home screening for colorectal cancer diminished less than that for colonoscopy and breast and cervical cancer screening. The authors have highlighted approaches for home cancer screening in addition to telemedicine.
Accessing Near-Infrared-Absorbing BF<sub>2</sub>-Azadipyrromethenes via a Push–Pull Effect (2014)

Novel aza-BODIPYs with significant bathochromic shifts were designed and synthesized by installation of strong electron-withdrawing groups on the para-positions of 1,7-phenyls and electron-donating groups on the para-positions of 3,4-phenyls. These dyes show strong NIR fluorescence emissions up to 756 nm, and absorptions up to 720 nm.
A robust algorithm for step 2 in 3G FDD W-CDMA synchronization (2002)

3G FDD W-CDMA initial synchronization follows a 3-step procedure to find a primary scrambling code while locating the frame boundary. In step 2, simplified coherent combining of secondary codes has been introduced for group and slot offset identification. The proposed method shows significant performance improvement against frequency offset. The simulation results show that there is approximately 3 dB performance improvement compared to conventional coherent integration for 6 kHz carrier offset while the other results follow almost the same values as those of conventional coherent integration.