gebhart/patrepeval huggingface dataset:
Manual of Photography: Photographic and Digital Imaging (2001)

From the Publisher:
The Manual of Photography is the standard work for anyone who is serious about photography: professional photographers and lab technicians or managers, as well as students and enthusiastic amateurs who want to become more technically competent. authors provide comprehensive and accessible coverage of the techniques and technologies of photography. The Manual now covers digital techniques, and a new colour plate section illustrates the chapters on colour techniques. Major new updates for the ninth edition include: coverage of digital techniques - more emphasis on electronic and hybrid media; and greater coverage of colour measurement, specification and reproduction - illustrated with a new colour plate section. Dealing with the fundamental principles as well as the practices of photography and imaging, the Manual covers topics ranging from optics to camera types and features, to colour photography and digital image processing and manipulation. Readership: Students on photography/digital imaging/art and design courses and those on computer courses needing to understand the scientific aspects.--BOOK JACKET.
The solid phase of the Ehrlich ascites tumor in mice. (1954)

Summary After the inoculation of 10–15 million Ehrlich ascites tumor cells, over 90 per cent of the mice developed solid tumors. Whenever these tumors lay in tissues adjacent to the peritoneum, there was established a region of direct continuity between these tissues and the peritoneal cavity. Particularly in regions of fluid stagnation within the peritoneum and of mesothelial denudation, semisolid tumors appeared. These masses were rich in tumor cells imbedded in a fibrin stroma. It is at least possible that the solid and semisolid phases of this tumor contribute cells which augment the number which appear in the ascitic suspension. The histologic identification of tumor cells in various viscera distant from the peritoneum indicates that tumor cells escape by way of the lymphatic drainage from this chamber and, in some locations, initiate metastases.
Electrochemical reduction and oxidation of C60 films (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemical reduction and oxidation of C60 filmsChristophe Jehoulet, Allen J. Bard, and Fred WudlCite this: J. Am. Chem. Soc. 1991, 113, 14, 5456–5457Publication Date (Print):July 1, 1991Publication History Published online1 May 2002Published inissue 1 July 1991https://pubs.acs.org/doi/10.1021/ja00014a049https://doi.org/10.1021/ja00014a049research-articleACS PublicationsRequest reuse permissionsArticle Views930Altmetric-Citations193LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tunable WDM dispersion compensation with fixed bandwidth and fixed passband center wavelength using a uniform FBG (2002)

We report an fiber Bragg grating-based tunable dispersion compensator with fixed bandwidth and fixed passband center wavelength for wavelength-division-multiplexing (WDM) channels. Chirping of the grating is achieved by bending a cantilever, and the tunability is realized by controlling the length of the induced chirping within a longer uniform grating. Due to the fixed center wavelength and bandwidth, crosstalk from adjacent wavelength bands is minimized and a single passband can potentially accommodate several WDM channels. We demonstrate tunable dispersion compensation up to 1500 ps/nm with a 10-cm uniform grating. Moreover, both negative and positive 400-ps/nm values are achieved in a single device with 2-nm bandwidth.
Localization of the meningococcal receptors for human transferrin (1993)

The interaction between gold-labelled human transferrin (Au-HTF) with live meningococci after growth in vivo or in different in vitro conditions was examined by electron microscopy to localize and quantify the numbers of HTF-binding sites on the cell surface. It was clearly demonstrated that HTF binds to the surface of live meningococci (of different serogroups and serotypes) after growth in either iron-sufficient or iron-restricted cultures, although the degree of labelling was always higher (2- to 35-fold) in the latter case. The commensal Neisseria polysaccharea behaved similarly. Ultrathin sections showed that Au-HTF was localized predominantly on the outer membrane of the cells and vesicles, with hardly any internalization. Au-HTF labelling on meningococci was significantly reduced after incubation with unlabelled HTF or with rabbit antiserum containing antibodies against transferrin-binding proteins (TBPs), demonstrating the specificity of the interaction. These sera also blocked binding between HTF and outer membrane proteins on Western immunoblots. Direct evidence of the expression of the TBPs (Western blots) and localization of the HTF receptor (electron microscopy) on in vivo-grown meningococci was obtained from organisms derived without laboratory culturing from the cerebrospinal fluid of a patient. There was considerable cell-to-cell variation in the amount of labelling present on cells of the same sample (in vitro- or in vivo-grown organisms) and between different strains. The degree of binding varied with time of incubation of the cells with Au-HTF. The gold particles frequently formed discrete circles on the cell surfaces of the in vitro-grown organisms; these circles appear to be associated with outer membrane vesicle formation. The results show that the TBPs, which form part of the active components of the HTF receptor(s), are expressed in vivo and are surface exposed and immunogenic and that antibodies against them can interfere with the HTF binding of the meningococcal cells, which may affect iron utilization. This study further supports the concept of regarding the TBPs as future vaccine candidates.
High-Speed Satellite Mobile Communications: Technologies and Challenges (2004)

Central features of future 4G mobile communication systems are high-speed data transmission (up to 1 Gb/s) and interactive multimedia services. For effective delivery of these services, the network must satisfy some stringent QoS metrics, defined typically in terms of maximum delay and/or minimum throughput. Mobile satellite systems will be fully integrated with the terrestrial cellular systems to provide ubiquitous global coverage to diverse users. The challenges for future broadband satellite systems, therefore, lie in the proper deployment of state-of-the-art satellite technologies to ensure seamless integration of the satellite networks into the cellular systems and its QoS frameworks, while achieving, as far as possible, efficient use of satellite link resources. The paper presents an overview of future high-speed satellite mobile communication systems, the technologies deployed or planned for deployment, and the challenges. Focusing in particular on nonlinear downlink channel behavior, shadowing and multipath fading, various physical channel models for characterizing the mobile satellite systems are presented. The most prominent technologies used in the physical layer, such as coding and modulation schemes, multiple-access techniques, diversity combining, etc., are then discussed in the context of satellite systems. High-speed and QoS-specific technologies, such as onboard processing and switching, mobility and resource management, IP routing and cross-layer designs, employed in the satellite systems are also discussed.
Preliminary studies on nasal decongestant activity from the seed of the shea butter tree, Butyrospermum parkii. (1979)

1 The seed of Butyrospermum parkii yields shea butter which according to local traditional healers relieves inflammation of the nostrils. 2 Since there is as yet no absolutely satisfactory nasal decongestant in clinical use, it was decided to investigate the effects of shea butter in nasal congestion. The substance was prepared in the laboratory. 3 The human subjects used were those suffering from rhinitis with moderate to severe nasal congestion. They were divided into the test group which received shea butter, the control group which was treated with xylometazoline and the 'placebo' group which received white petroleum jelly B.P. 4 The results showed that nasal congestion was relieved more satisfactorily in the test group than in the other two groups. 5 It is concluded that shea butter may prove more efficacious in nasal congestion than conventional nasal drops.
986. Potential bronchodilators in the flavonoid series (1962)

D. Kidd, J. Chem. Soc., 1962, 5121 DOI: 10.1039/JR9620005121
Amino acid sequence studies on the .alpha. chain of human fibrinogen. Exact location of crosslinking acceptor sites (1979)

Human fibrinogen was clotted under conditions that promote latent factor XIII activity and in the presence of a radioactive substitute cross-linking donor ([14C]glycine ethyl ester). The labeled fibrin was reduced and alkylated in the presence of 6 M guanidinium chloride. After dialysis and freeze-drying, the preparation was separated into its constituent polypeptide subunits by chromatography on (carboxymethyl)cellulose in the presence of 8 M urea. Under the incorporation conditions used, the radioactivity was limited to gamma chains (one donor molecule/chain) and alpha chains (two donor molecules/chain). The labeled alpha chains were digested with cyanogen bromide and fractionated on Sephadex G-50. All the radioactivity was found in a fragment previously designated H alpha CNI, the largest of the cyanogen bromide fragments in the alpha chain. The fragment was further fragmented by digestion with plasmin, trypsin, chymotrypsin, and/or staphylococcal protease. The incorporated radioactivity was found to reside in equal amounts at two different sites located 38 residues apart. These were determined to be positions 88 and 126 in H alpha CNI, which correspond to glutamine-328 and glutamine-366 in the alpha chain.
Capacitor regenerative braking control of power-assisted wheelchair for safety downhill road driving (2010)

This paper describes a capacitor regenerative braking control scheme of electric power-assisted wheelchairs for safety driving on downhill roads. The “electric power assisted wheelchair” which assists the driving force by electric motors is expected to be widely used as a mobility support system for elderly people and disabled people; however, it has no braking system to suppress the wheelchair's velocity and brings the dangerous and fearful driving especially on downhill roads. Therefore this paper proposes a novel safety and efficient driving control scheme based on the capacitor regenerative braking system. This study applies the regenerative braking system with the step-up/down chopper circuit with additional resistance and realizes the velocity feedback control with the variable duty ratio so that it tracks the smooth velocity based on Minimum Jerk Model. In addition, the reference velocity is flexibly designed according to the declined angle. Some driving experiments on the practical downhill roads show the effectiveness of the proposed control system.
Capacity Planning for Virtualized Servers (2006)

Today&apos;s data centres offer many different IT services mostly hosted on dedicated physical servers. Virtualization provides a technical means for server consolidation leading to increased server utilization. The term refers to the abstraction of computing resources across many aspects of computing and has been used to describe different techniques. Virtualization engines allow hosting multiple virtual servers (including operating system plus applications) on a single physical server, and sometimes to migrate and dynamically allocate these virtual servers to physical servers on demand. This allows for much flexibility in capacity management. This article presents a number of capacity planning problems in the presence of virtualized IT infrastructures and decision models to allocate these virtual servers optimally. Based on a data set of CPU traces from a data centre provider, we present the results of experiments using different problem formulations. 1
Studies with <i>S</i>‐alkylpyrimidine: New route for the synthesis derivatives of isoxazol, pyrazolo[1,5‐<i>a</i>]pyrimidine, pyridazine, pyridine, thieno[2,3‐<i>b</i>]pyridine and thiophene of potential anti‐HIV (2008)

Abstract magnified image Derivatives of thiophene, thieno[2,3‐ b ]pyridine, pyridine, isoxazol, pyrazolo[1,5‐ a ]pyridine, pyridazine linked with s‐pyrimidine derivative have been synthesized and tested for antimicrobial and antifungal activities. The structure of the newly synthesized compounds have been established on the basis of their analytical and spectral data.
Use of Interwire Ultrasonic Leakage to Quantify Loss of Prestress in Multiwire Tendons (2011)

This paper presents a technique developed on the basis of ultrasonic guided waves to monitor prestress levels in multiwire prestressing strands. The transducer layout identified for stress measurement is composed of an ultrasound excitation provided by a piezoelectric element bonded on a peripheral wire. Ultrasound detection is performed on the central and peripheral wires at the strand’s end. The ultrasonic feature used for stress monitoring is the interwire leakage between the peripheral and the central wire, occurring across the strand anchorage. A semianalytical finite-element analysis is first used to predict modal and forced wave solutions in seven-wire strands as a function of the applied prestress level. The numerical analysis accounts for the changing interwire contact as a function of applied loads and predicts the attenuation occurring in loaded strand when the wave travels across the anchorage. Results of load monitoring in free strands during laboratory tests are then presented. Finally, a statistical approach is used to enhance the sensitivity of the technique to stress level in the strands. The study presented focuses on unbonded tendons. However, the final goal of the research is to monitor prestress loss in bonded tendons that are found in the majority of the bridges built in California.
Sintesis de heterociclos a partir de derivados de isoxazol (1987)

De acuerdo con toda la informacion bibliografica existente acerca de la apertura de isoxazoles y sales de n-alquilisoxazolio se estudia el comportamiento de 5-metil isoxazoles con grupos atractores de electrones en posicion c-4 sales de isoxazolio 5-sustituidas sales de 5-metilisoxazolio con grupos atractores de electrones en posicion c-4 y sales de isoxazolio 3 5-disustituidas frente a diferentes 1 2-dinucleofilos 1 3-dinucleofilos compuestos con metilenos activos o cianamida. Se observa la produccion de diferentes compuestos de cadena abierta y ciclacion posterior de dichos productos para formar diversos compuestos heterociclicos
Bioavailability Study of Commercial Sustained-Release Preparations of Diclofenac Sodium in Gastrointestinal Physiology Regulated-Dogs. (1992)

The gastrointestinal (GI) physiology of beagle dogs was regulated with a combined-treatment of intramuscular pentagastrin (10 micrograms/kg x 2) and intravenous atropine sulfate (0.02 mg/kg x 1). Here, the gastric acidity, the gastric emptying time and the small intestinal transit time in the regulated-dogs were respectively around pH 2, 0.7h and 4h, approximating those in healthy humans. The superiority of the regulated-dogs over the intact dogs was confirmed in comparative bioavailability studies by using two classes of commercial preparations. Both the conventional tablet and the sustained-release capsule of diclofenac sodium exhibited simple and similar average plasma concentration-time curves of free diclofenac in the intact dogs, while the latter preparation is reported to reveal a bimodal plasma curve of the drug in healthy humans. The regulated-dogs, however, permitted a bimodal average plasma pattern of the drug for the capsules due to an approximation of the GI physiology between humans and these classes of the dogs. The combined-treatment of beagle dogs with pentagastrin and atropine sulfate seems to supply a useful animal model in predicting the absorption characteristics of the sustained-release preparations and poor water-soluble drugs.
Coenzyme A biosynthesis: an antimicrobial drug target (2008)

Pantothenic acid, a precursor of coenzyme A (CoA), is essential for the growth of pathogenic microorganisms. Since the structure of pantothenic acid was determined, many analogues of this essential metabolite have been prepared. Several have been demonstrated to exert an antimicrobial effect against a range of microorganisms by inhibiting the utilization of pantothenic acid, validating pantothenic acid utilization as a potential novel antimicrobial drug target. This review commences with an overview of the mechanisms by which various microorganisms acquire the pantothenic acid they require for growth, and the universal CoA biosynthesis pathway by which pantothenic acid is converted into CoA. A detailed survey of studies that have investigated the inhibitory activity of analogues of pantothenic acid and other precursors of CoA follows. The potential of inhibitors of both pantothenic acid utilization and biosynthesis as novel antibacterial, antifungal and antimalarial agents is discussed, focusing on inhibitors and substrates of pantothenate kinase, the enzyme catalysing the rate-limiting step of CoA biosynthesis in many organisms. The best strategies are considered for identifying inhibitors of pantothenic acid utilization and biosynthesis that are potent and selective inhibitors of microbial growth and that may be suitable for use as chemotherapeutic agents in humans.
Naturally-farrowed, artificially-reared pigs as an alternative model for experimental infection by Haemophilus parasuis. (2003)

The use of naturally-farrowed, artificially-reared piglets as an alternative model to study Haemophilus parasuis infections was evaluated. Two trials were performed in order to evaluate the proposed model. In trial 1, animals were vaccinated and challenged with H. parasuis. Results showed that the proposed model was effectively used to evaluate protective immunity against this organism. In trial 2, animals were challenged with different doses of H. parasuis. Results showed that the severity of clinical signs and lesions tended to increase with higher doses. The reproduction of clinical signs and lesions characteristic of H. parasuis systemic infection was successful in both trials, proving that this model is a viable alternative to specific-pathogen free and cesarean-derived, colostrum-deprived pigs.
Intra-Erythrocyte Infusion of Dexamethasone Reduces Neurological Symptoms in Ataxia Teleangiectasia Patients: Results of a Phase 2 Trial (2014)

Current Controlled Trial 2010-022315-19SpA.
Investigation of a Nosocomial Outbreak of Imipenem-Resistant <i>Acinetobacter baumannii</i> Producing the OXA-23 β-Lactamase in Korea (2005)

We investigated an outbreak of Acinetobacter baumannii in an intensive care unit and in the surgery, medicine, neurology, and urology wards of the Kosin University Gospel Hospital in Busan, Korea. The outbreak involved 36 cases of infection by A. baumannii producing the OXA-23 beta-lactamase over an 8-month period and was caused by a single pulsed-field gel electrophoresis clone. The epidemic isolates were characterized by a modified cloverleaf synergy test. Isoelectric focusing of crude bacterial extracts detected one nitrocefin-positive band with a pI value of 6.65. PCR amplification and characterization of the amplicons by direct sequencing indicated that the epidemic isolates carried a bla(OXA-23) determinant. The epidemic isolates were characterized by a multidrug resistance phenotype that remained unchanged over the outbreak, including penicillins, cephamycins, extended-spectrum cephalosporins, carbapenems, monobactams, and aminoglycosides. This study shows that the bla(OXA-23) resistance determinant may become an emerging therapeutic problem.
Increased Risk of Cancer among Siblings of Long-term Childhood Cancer Survivors: A Report from the Childhood Cancer Survivor Study (2005)

We determined risk of cancer among first-degree relatives of 5-year survivors of childhood leukemia, lymphoma, central nervous system tumors, sarcomas, Wilms' tumor, and neuroblastoma. Subjects were 13,703 participants in the Childhood Cancer Survivor Study. Family history was collected on 56,759 first-degree relatives using a self-reported questionnaire. Incidence was compared with age- and sex-specific rates using the U.S. Surveillance, Epidemiology and End Results program. Siblings of the survivors had an increased risk of cancer [standardized incidence ratio (SIR), 1.5; 95% confidence interval (95% CI), 1.35-1.7]. Risk was elevated for siblings of probands of leukemia (SIR, 1.3; 95% CI, 1.0-1.6), Hodgkin's disease (SIR, 1.5; 95% CI, 1.2-1.9), non-Hodgkin's lymphoma (SIR, 1.8; 95% CI, 1.3-2.5), Wilms' tumor (SIR, 1.9; 95% CI, 1.2-3.2), soft tissue sarcoma (SIR, 1.5; 95% CI, 1.0-2.2), and bone tumors (SIR, 1.6; 95% CI, 1.2-2.2). Cancer risk was elevated in siblings (SIR, 2.4; 95% CI, 1.5-3.7) and offspring (SIR, 15.0; 95% CI, 5.3-42.9) of probands with second malignant neoplasms (SMN) compared with relatives of probands without SMNs. Siblings of probands with leukemia, Hodgkin's disease, neuroblastoma, and Wilms' tumor had elevated risks for the same malignancies. Parents had no increased risk (fathers' SIR, 0.7; 95% CI, 0.7-0.8; mothers' SIR, 0.9; 95% CI, 0.9-1.0). Seventy percent of siblings' cancers developed in adulthood. These findings suggest that familial cancer syndromes may be revealed as this cohort and family members age and with accrual of more offspring and subjects with SMNs.
Major histocompatibility complex (MHC) class I K<sup>b</sup>D<sup>b</sup>−/− deficient mice possess functional CD8+ T cells and natural killer cells (1998)

We obtained mice deficient for major histocompatibility complex (MHC) molecules encoded by the H-2K and H-2D genes. H-2 KbDb -/- mice express no detectable classical MHC class I-region associated (Ia) heavy chains, although beta2-microglobulin and the nonclassical class Ib proteins examined are expressed normally. KbDb -/- mice have greatly reduced numbers of mature CD8+ T cells, indicating that selection of the vast majority (>90%) of CD8+ T cells cannot be compensated for by beta2-microglobulin-associated molecules other than classical H-2K and D locus products. In accord with the greatly reduced number of CD8+ T cells, spleen cells from KbDb -/- mice do not generate cytotoxic responses in primary mixed-lymphocyte cultures against MHC-disparate (allogeneic) cells. However, in vivo priming of KbDb -/- mice with allogeneic cells resulted in strong CD8+ MHC class Ia-specific allogeneic responses. Thus, a minor population of functionally competent peripheral CD8+ T cells capable of strong cytotoxic activity arises in the complete absence of classical MHC class Ia molecules. KbDb -/- animals also have natural killer cells that retain their cytotoxic potential.