gebhart/patrepeval huggingface dataset:
Performance of a Quality-Assessment Scheme for Blood Glucose Meters in General Practice (1985)

We describe our experience with a quality-assessment scheme for Glucometer users in General Practice based on simultaneous blood samples taken on filter paper strips and posted to the laboratory. The accuracy of results from these blood glucose meters outside the laboratory was below generally accepted laboratory standards; 30% of results fell outside +/- 20% of the laboratory value. Only 58% of the filter paper strips sent out were returned for analysis, suggesting a lack of awareness of the benefits and importance of such a scheme by the G.P. Glucometer users.
Polycyclic aromatic hydrocarbons (PAHs) adsorption on solid surfaces applied to waste lubricant oils recovery process (2010)

Abstract Lubricant oils undergo degradation increasing polycyclic aromatic hydrocarbons (PAHs) concentration. In this work, PAHs adsorption onto activated carbon, powder silica, and powder chitosan surfaces was estimated, with their concentrations in organic solvents (ethanol, 2‐propanol, 1‐butanol, and terc ‐butanol) monitored by UV‐visible absorption. Equilibrium concentration was attained after 72 h and the isotherms presented characteristic of multilayer formation. The greater surface density was determined for the chitosan, but the system containing activated carbon and 1‐butanol presented better efficiency for PAHs removal. Results indicated that the adsorption evaluated in this work can be a potential stage in the waste lubricant oils global recovery process.
The Structure of Paraldol (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure of ParaldolMartin Vogel and David RhumCite this: J. Org. Chem. 1966, 31, 6, 1775–1780Publication Date (Print):June 1, 1966Publication History Published online1 May 2002Published inissue 1 June 1966https://pubs.acs.org/doi/10.1021/jo01344a025https://doi.org/10.1021/jo01344a025research-articleACS PublicationsRequest reuse permissionsArticle Views123Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Detachment and reorientation of cells using near-infrared laser microbeam (2011)

Reorientation of adhering cell(s) with respect to other cell(s) has not been yet possible, thus limiting study of controlled interaction between cells. Here, we report cell detachment upon irradiation with a focused near-infrared laser beam, and reorientation of adherent cells. The detached cell was transported along the axial direction by scattering force and trapped at a higher plane inside the media using the same laser beam by a gravito-optical trap. The trapped cell could then be repositioned by movement of the sample stage and reoriented by rotation of the astigmatic trapping beam. The height at which the cell was stably held was found to depend on the laser beam power. Viability of the detached and manipulated cell was found not to be compromised as confirmed by propidium iodide fluorescence exclusion assay. The reoriented cell was allowed to reattach to the substrate at a controlled distance and orientation with respect to other cells. Further, the cell was found to retain its shape even after multiple detachments and manipulation using the laser beam. This technique opens up new avenues for noncontact modification of cellular orientations that will enable study of intercellular interactions and design of engineered tissue.
What is a normal rate of weight gain in infancy? (1994)

We have retrieved weights from the Child Health records of an annual cohort of 3418 full-term children, aged 18-30 months in order to define a lower limit of normality for weight gain for both clinical and research purposes. There was a strong tendency for children at the extremes of the distribution to move inwards towards the average: only 26% of those below the 3rd centile for weight at six weeks were still below it at one year. We describe a method based on conditional standards to correct for this "regression to the mean" and produce a measure of the discrepancy between a child's predicted and actual growth: the "thrive index". The value of the thrive index below which only a minority of children fell provided a lower threshold for normality. While most children below the 3rd centile for weight at 9-24 months of age also had subnormal weight gain, 41% of those with subnormal weight gain had not fallen below the 3rd centile.
A Non-manipulable Meeting Scheduling System (1994)

In this paper we present three scheduling mechanisms that are manipulation-proof for closed systems. The amount of information that each user must encode in the mechanism increases with the complexity of the mechanism. On the other hand, the more complex the mechanism is, the more it maintains the privacy of the users. The first mechanism is a centralized, calendar-oriented one. It is the least computationally complex of the three, but does not maintain user privacy. The second is a distributed meeting-oriented mechanism that maintains user privacy, but at the cost of greater computational complexity. The third mechanism, while being the most complex, maintains user privacy (for the most part) and allows users to have the greatest influence on the resulting schedule.
Amphetamine Self-Administration in Light and Moderate Drinkers (2010)

These results are consistent with those from previous laboratory experiments and suggest that moderate alcohol consumption may increase vulnerability to the abuse-related effects of stimulants.
Targeting the PAC1 Receptor for Neurological and Metabolic Disorders (2019)

The pituitary adenylate cyclase-activating polypeptide (PACAP)-selective PAC1 receptor (PAC1R, ADCYAP1R1) is a member of the vasoactive intestinal peptide (VIP)/secretin/glucagon family of G protein-coupled receptors (GPCRs). PAC1R has been shown to play crucial roles in the central and peripheral nervous systems. The activation of PAC1R initiates diverse downstream signal transduction pathways, including adenylyl cyclase, phospholipase C, MEK/ERK, and Akt pathways that regulate a number of physiological systems to maintain functional homeostasis. Accordingly, at times of tissue injury or insult, PACAP/PAC1R activation of these pathways can be trophic to blunt or delay apoptotic events and enhance cell survival. Enhancing PAC1R signaling under these conditions has the potential to mitigate cellular damages associated with cerebrovascular trauma (including stroke), neurodegeneration (such as Parkinson's and Alzheimer's disease), or peripheral organ insults. Conversely, maladaptive PACAP/PAC1R signaling has been implicated in a number of disorders, including stressrelated psychopathologies (i.e., depression, posttraumatic stress disorder, and related abnormalities), chronic pain and migraine, and metabolic diseases; abrogating PAC1R signaling under these pathological conditions represent opportunities for therapeutic intervention. Given the diverse PAC1R-mediated biological activities, the receptor has emerged as a relevant pharmaceutical target. In this review, we first describe the current knowledge regarding the molecular structure, dynamics, and function of PAC1R. Then, we discuss the roles of PACAP and PAC1R in the activation of a variety of signaling cascades related to the physiology and diseases of the nervous system. Lastly, we examine current drug design and development of peptides and small molecules targeting PAC1R based on a number of structure- activity relationship studies and key pharmacophore elements. At present, the rational design of PAC1R-selective peptide or small-molecule therapeutics is largely hindered by the lack of structural information regarding PAC1R activation mechanisms, the PACAP-PAC1R interface, and the core segments involved in receptor activation. Understanding the molecular basis governing the PACAP interactions with its different cognate receptors will undoubtedly provide a basis for the development and/or refinement of receptor-selective therapeutics.
Order or chaos? An evaluation of the regulation of protein kinase CK2 (2004)

CK2 is a highly conserved, ubiquitously expressed protein serine/threonine kinase present in all eukaryotes. Circumscribed as having a vast array of substrates located in a number of cellular compartments, CK2 has been implicated in critical cellular processes such as proliferation, apoptosis, differentiation, and transformation. Despite advances in elucidating its substrates and involvement in cellular regulation, its precise mode of regulation remains poorly defined. In this respect, there are currently conflicting views as to whether CK2 is constitutively active or modulated in response to specific stimuli. Perhaps an important consideration in resolving these apparent discrepancies is recognition of the existence of many discrete CK2 subpopulations that are distinguished from one another by localization or association with distinct cellular components. The existence of these subpopulations brings to light the possibility of each population being regulated independently rather than the entire cellular CK2 content being regulated globally. Logically, each local population may then be regulated in a distinct manner to carry out its precise function(s). This review will examine those mechanisms including regulated expression and assembly of CK2 subunits, phosphorylation of CK2, and interactions with small molecules or cellular proteins that could contribute to the local regulation of distinct CK2 populations.
Coherent optical processing of Gabor and wavelet expansions of one- and two-dimensional signals (1992)

Recent development in vision and image understanding related study reveals that a signal decomposition before processing may provide an enormous amount of useful information aboutthe signal. Various signal decomposition models such as the Gabor and wavelet expansions have been proposed. While the Gabor signal expansion creates a fixed resolution space-frequency signal representation, the wavelet transform provides a multiresolution signal space-scale decomposition. Digital implementation of these expansions are computationally intensive both because of the nature of the coordinate-doubling of the transforms and because ofthe large quantity of convolution/correlation operations to be performed. Optics with its inherent parallel-processing capability has been applied to many useful linear signal and image transformations for feature analysis and extraction. We studied the suitability of using optical processing techniques for the signal Gabor and wavelet analysis. Gabor and wavelet expansions of both 1- and 2-D signals and images are discussed. System parameters and limitations are analyzed. Preliminary experimental results are presented.
Dual-band infrared perfect absorber based on asymmetric T-shaped plasmonic array (2014)

An infrared dual-band perfect absorber based on asymmetric T-shaped plasmonic array is designed and numerically investigated. Two distinct absorption peaks are achieved by localized surface plasmon polariton (LSPP) mode over a wide incident angular range. Both the absorption peaks can be finely tuned independently by varying the geometry of the structure. In our proposed structure, the period of the T-shaped structures becomes less and the multiple LSPP peaks are suppressed, which result in the sideband of absorption peaks very low. This dual-band perfect absorber has potential applications such as in infrared imaging devices, thermal bolometers, and wavelength selective radiators.
ESD Protection Design And Applications To Bidirectional Antenna Protection For Sub-5 nm Gate Oxides (1997)

In this paper, the main aspects of ESD protection design requirements are reviewed, and the applications to antenna protection design are presented. It is shown that in order to protect gate oxides of 1 A), short duratioln (< 200 ns) pulse which can cause severe damage to the small circuits in the IC. Semiconductor devices have always been exposed to ESD, but it is only with the advent of CMOS technologies, with relatively thin oxides and shallow junctions, that ESD damage became a serious reliability concern. Over the period of about 20 yeiars, the approach to ESD in ICs has changed tremendously. It has moved from a reactive one, where failures and protection were handled as they occurred, to a more proactive one, where test methods, simulations and analytical approaches have been developed to anticipate and resolve problems very early in the design cycle. Issues thist had to be addressed in the process were the standardization of test methods for reproducing ESD failures in a controlled environment, and the understanding of the physics of the conduction mechanisms during high cument conduction. While these issues have not been completely resolved, enough progress has been made to thist good protection circuits can be designed with high levels of ESD protection. In parallel, better understanding of the device physics has led to deep submicron technologies being characterized and developed with a view to improving their intrinsic high current capability. [n this paper, the main protection circuit techniques used for ESD, and the applicability to the design of antenna protection circuits will be discussed. The purpose of the paper is to identify aspects of the ESD work which can be used and extended to the development and undeirstanding antenna protection circuit design.
Dynamic overmodulation in the synchronous reference frame for IPMSMs (2012)

Overmodulation is frequently required during the transient interval at high speed operations of interior permanent magnet synchronous motors (IPMSMs). In this work, an overmodulation method is developed in the synchronous reference frame with a provision of assigning different priorities to d and q-axes currents. During the current boosting in motoring, the d-axis current is increased by priority to minimize the overmodulation period. However in the regeneration process, the q-axis current is decreased by priority during a load reduction. Simulation and experimental results show that the proposed method, compared with the existing minimum-phase error method, in shortening the overmodulation period.
Alveolar macrophage function in rats with severe protein calorie malnutrition. Arachidonic acid metabolism, cytokine release, and antimicrobial activity. (1990)

To investigate the effects of protein calorie malnutrition (PCM) on alveolar macrophage function, we measured antimicrobial activity, IL-1 and TNF production, and arachidonic acid metabolism in alveolar macrophages of infant rats with moderate and severe PCM. Groups of weanling male rats were fed a diet containing 0.8% protein (PCM) or 24% protein (control). A third group (pair fed) was fed limited amounts of the control diet that matched the mean daily dietary intake of the PCM group. After 4 wk on the diets, alveolar macrophages from all three groups functioned similarly with respect to surface adherence, phagocytosis and killing of Listeria monocytogenes, release of hydrogen peroxide and superoxide anion, and production of IL-1 and TNF. In contrast, Listeria-stimulated alveolar macrophages from the PCM group exhibited a marked shift in arachidonic acid metabolism, with impaired production of leukotriene B4 and enhanced release of thromboxane B2 and PGE2. The membrane arachidonic acid content and the uptake of [3H]arachidonate by alveolar macrophages did not differ among the three groups. The shift toward the cyclooxygenase pathway was not seen after 2 wk of dietary restriction and was reversed if PCM animals were fed the control diet for 1 wk. Thus, PCM does not affect the antimicrobial activity or cytokine production of alveolar macrophages, but causes alterations in arachidonic acid metabolism that may interfere with the modulatory functions of alveolar macrophages.
19 Fa nd 1 H MRI detection of amyloid b plaques in vivo (2005)

Formation of senile plaques composed of amyloid b peptide, a pathological hallmark of Alzheimer disease, in human brains precedes disease onset by many years. Noninvasive detection of such plaques could be critical in presymptomatic diagnosis and could contribute to early preventive treatment strategies. Using amyloid precursor protein (APP) transgenic mice as a model of amyloid b amyloidosis, we demonstrate here that an intravenously administered 19 F-containing amyloidophilic compound labels brain plaques and allows them to be visualized in living mice by magnetic resonance imaging (MRI) using 19 F and 1 H. Our findings provide a new direction for specific noninvasive amyloid imaging without the danger of exposure to radiation. This approach could be used in longitudinal studies in mouse models of Alzheimer disease to search for biomarkers associated with amyloid b pathology as well as to track disease course after treatment with
Synthesis of Isomerically Pure Organodihydrofullerenes (1993)

Abstract Controlled two‐step nucleophilic hydroalkylations, hydroar‐ylations as well as hydrostannylations of fullerene‐60 ( 1 ) and fullerene‐70 ( 2 ) lead to defined organodihydrofullerenes C 60 HR and C 70 HR. NMR investigations show that only one isomer of each organodihydrofullerene with C s symmetry is formed. In all cases the addition takes place at a double bond separating two six‐membered rings of the fullerene core. In this way a variety of organodihydrofullerenes also carrying functional groups have been synthesized.
CHEMICAL AND ENGINEERING NEWS (1947)

RETURN TO ISSUEPREVNewsNEXTCHEMICAL AND ENGINEERING NEWSWALTER J. MURPHYCite this: Chem. Eng. News 1947, 25, 45, 3277Publication Date (Print):November 10, 1947Publication History Published online5 November 2010Published inissue 10 November 1947https://pubs.acs.org/doi/10.1021/cen-v025n045.p3277https://doi.org/10.1021/cen-v025n045.p3277newsACS PublicationsCopyright © 1947 AMERICAN CHEMICAL SOCIETYArticle Views2Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Chemical engineering and industrial chemistry Get e-Alerts
Using Hierarchical EM to Extract Planes from 3D Range Scans (2006)

Recently, the acquisition of three-dimensional maps has become more and more popular. This is motivated by the fact that robots act in the three-dimensional world and several tasks such as path planning or localizing objects can be carried out more reliable using three-dimensional representations. In this paper we consider the problem of extracting planes from three-dimensional range data. In contrast to previous approaches our algorithm uses a hierarchical variant of the popular Expectation Maximization (EM) algorithm [1] to simultaneously learn the main directions of the planar structures. These main directions are then used to correct the position and orientation of planes. In practical experiments carried out with real data and in simulations we demonstrate that our algorithm can accurately extract planes and their orientation from range data.
Analysis of the effects of blade pitch on the radar return signal from rotating aircraft blades (1992)

The analysis considers only propeller blades. This is partly because rotor blades will also have cyclic pitch, in order to reduce the roll caused by the asymmetry of lift between advancing and retreating blades, and partly because rotor blades are so large and their pitch is so small that the effect of any AM on the return signal will be small in comparison. Simulated returns and frequency spectra are plotted and discussed.
80960-next generation (2003)

A discussion is presented of the next generation core for the 80960 family of embedded processor chips. It is shown that the next generation 960 core incorporates several features for high performance. It has wide and concurrent internal buses. It can decode and issue a sustained two instructions per clock even with loads and branches. It implements branch lookahead with branch prediction to minimize pipeline breaks. It manages the parallelism and multiple functional units by using resource scoreboarding techniques. It is a modular, high-performance core designed for the embedded processor market. The goals of the core design, the basic microarchitecture, the pipeline, and the key performance features are examined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Reduction of threshold noise in fm receivers operating in quasisynchronous field (1985)

The threshold effect is a phenomenon experienced in the reception of frequency modulated (FM) signals. It is found to be particularly troublesome in FM quasisynchronous (QS) mobile radio schemes, in the parts of the coverage area where carrier cancellation occurs due to carrier components interaction. This results in sharp noise bursts punctuating the receiver output and a consequent degradation in the speech quality. The paper describes a technique which was implemented as a receiver modification in the form of an add-on unit for the purpose of minimising the threshold noise effects with satisfactory results. Measurements conducted on a commercial receiver incorporating this modification revealed that an improvement of 12 dB in the output S/N was achieved.
Compact 1×16 power splitter based on symmetrical1×2MMI splitters (1994)

First experimental results of compact 1×16 splitters based on single 1×2 multimode interference (MMI) power splitters in alumina waveguides on silicon are reported.
An Algebraic Method to Determine If a Point is on a Spline (1984)

This study is concerned with a parametrically defined spline and a point in space. If the point is on the spline, a determination is also made of the bay of the spline where the point lies and the parametric value in the bay that corresponds to the point. The splines are cubic and are represented in the normalized Hermite form. Splines in other forms can be converted into this form. Because the method of solution is algebraic in nature, it should be much faster than existing analytic-iterative-recursive techniques.