gebhart/patrepeval huggingface dataset:
Understanding I/O performance behaviors of cloud storage from a client's perspective (2016)

Cloud storage has gained increasing popularity in the past few years. In cloud storage, data is stored in the service provider's data centers, and users access data via the network. For such a new storage model, our prior wisdom about conventional storage may not remain valid nor applicable to the emerging cloud storage. In this paper, we present a comprehensive study and attempt to gain insight into the unique characteristics of cloud storage, primarily from the client's perspective. Through extensive experiments and quantitative analysis, we have acquired several interesting, and in some cases unexpected, findings. (1) Parallelizing I/Os and increasing request sizes are keys to improving the performance, but optimal bandwidth may only be achieved with a proper combination of parallelism and request size. (2) Client capabilities, including CPU, memory, and storage, play an unexpectedly important role in determining the achievable performance. (3) A geographically long distance affects client-perceived performance but does not always result in lower bandwidth and longer latency. Based on our experimental studies, we further present a case study on appropriate chunking and parallelization in a cloud storage client. Our studies show that specific attention should be paid to fully exploiting the capabilities of clients and the great potential of cloud storage services.
Olfactory training is helpful in postinfectious olfactory loss: A randomized, controlled, multicenter study (2013)

1b.
Regional ejection fraction and regional area strain for left ventricular function assessment in male patients after first-time myocardial infarction (2015)

In this work, we present a method to assess left ventricle (LV) regional function from cardiac magnetic resonance (CMR) imaging based on the regional ejection fraction (REF) and regional area strain (RAS). CMR scans were performed for 30 patients after first-time myocardial infarction (MI) and nine age- and sex-matched healthy volunteers. The CMR images were processed to reconstruct three-dimensional LV geometry, and the REF and RAS in a 16-segment model were computed using our proposed methodology. The method of computing the REF was tested and shown to be robust against variation in user input. Furthermore, analysis of data was feasible in all patients and healthy volunteers without any exclusions. The REF correlated well with the RAS in a nonlinear manner (quadratic fit-R(2) = 0.88). In patients after first-time MI, the REF and RAS were significantly reduced across all 16 segments (REF: p < 0.05; RAS: p < 0.01). Moreover, the REF and RAS significantly decreased with the extent of transmural scar obtained from late gadolinium-enhanced CMR images. In addition, we show that the REF and RAS can be used to identify regions with compromised function in the patients with preserved global ejection fraction with reasonable accuracy (more than 78%). These preliminary results confirmed the validity of our approach for accurate analysis of LV regional function. Our approach potentially offers physicians new insights into the local characteristics of the myocardial mechanics after a MI.
EFFECT OF SiC NANO SIZING ON SELF-CRACK- HEALING DURING SERVICE (2007)

Phone: +81-45-339-4026 Fax: +81-45-339-4024 wnakao@ynu.ac.jp http://www.bsk.ynu.ac.jp/~andolab/ In the present study, the efficient temperature region for in-situ self-crack-healing was improved by SiC nano-sizing. The present study adapted the following self assemble reaction to synthesis method alumina composite containing nano-size silicon carbide particles 3(3Al
<i>Pseudomonas aeruginosa</i>adherence to human basement membrane collagen<i>in vitro</i> (2003)

The mechanisms for Pseudomonas aeruginosa colonisation in the airways of patients with bronchiectasis and cystic fibrosis are poorly understood. P. aeruginosa could evade mucociliary clearance by adhering to the basement membrane at areas denuded of intact respiratory epithelium. The authors have developed an in vitro model to study P. aeruginosa adherence to human basement membrane type-IV collagen by using scanning electron microscopy. P. aeruginosa adherence density was determined as the number of P. aeruginosa per 20 microscope fields (2,000x) to log inocular size after incubation at 37 degrees C for 45 min. The presence of phytohaemagglutinin (PHA)-E, which binds specifically to D-galactose-beta1-4-D-N-acetylglucosamine, significantly reduced P. aeruginosa adherence density compared with control. The presence of heparin and calcium also significantly reduced P. aeruginosa adherence density. P. aeruginosa adherence was not affected by the presence of proline, trans-hydroxyproline, glycine, galactose, N-acetylneuraminic acid, N-acetylglucosamine or Arachis hypogea. Pseudomonas aeruginosa adherence probably acts via recognition of the D-galactose-beta1-4-D-N-acetylglucosamine sequence on type-IV collagen and this process could be inhibited by heparin and calcium. As persistent Pseudomonas aeruginosa colonisation is detrimental to patients with cystic fibrosis and bronchiectasis and there is currently no effective treatment for its eradication, these results could lead to novel therapy for persistent Pseudomonas aeruginosa infection.
In vitro decondensation of mammalian sperm and subsequent formation of pronuclei‐like structures for micromanipulation (1992)

In this study, we describe an efficient protocol for the formation of in vitro developed pronuclei for micromanipulation techniques. Our approach involved incubation of demembranated or permeabilized mammalian sperm in a phosphate buffer supplemented with heparin and beta-mercaptoethanol. Under the prevailing conditions, we achieved a uniform and reliable synchronous decondensation of sperm nuclear DNA. This initial decondensation facilitated the removal of mammalian protamines upon subsequent incubation in an amphibian egg extract. The interchange of protamines for histones to stabilize the DNA structure is recognized as a prerequisite for pronuclear formation. Furthermore, immunocytochemical studies have revealed that pronuclear development is accompanied by the formation of a nuclear lamina with corresponding DNA synthesis. The method described gave a high yield of nuclei during pronuclear formation. Ultimately, our aim is to transfer the in vitro-developed pronuclei into mammalian oocytes by micromanipulation. This novel procedure may prove useful in alleviating severe male factor problems especially in oligozoospermic cases in our in vitro fertilization center.
Controlled synthesis of low polydispersity Ag@SiO2 core–shell nanoparticles for use in plasmonic applications (2013)

A novel methodology was developed for the synthesis of tuneable silver–silica core–shell nanoparticles (Ag@SiO2). The use of tannic acid and sodium citrate to reduce and stabilize silver atoms allowed the controlled synthesis of silver cores ranging from 26–118 nm in diameter, and silica shells of tuneable thicknesses from 6–51 nm were deposited using a combination of tetraethyl orthosilicate and sodium citrate. Both core size and spacer thickness can be tuned over a wide range of diameters and thicknesses by the simple variation of the reagent stoichiometric ratios, and mg range quantities of highly uniform core–shell nanoparticles can be prepared with excellent repeatability and reproducibility. To ascertain the usefulness of the core–shell nanoparticles for plasmonic enhancement studies, fluorescence measurements were performed on core–shell and coreless nanoparticles coated with a molecular fluorophore.
Dialoging citizenship in Queensland: the ability to engage or estrange (2005)

This paper considers several discursive processes involved in an example of citizen–government dialogue. The relationship enacted occurs daily in each of our communities andhere involves samples of Queensland legislative practice, representing the government’sposition, and excerpts from interviews undertaken with young males who have experiencedeither formal school exclusion or first-time incarceration. Constructions of identity, central tothe concept of citizenship, are explored through two prominent discourses signalled in theexchange: individualism and moral/behavioural. These dialogue-based relationships offerdescriptive insight into processes through which marginalisation occur yet they also disclosevaluable options for sustaining ongoing conversation. As institutions of the twenty-first centuryreposition to embrace a more participatory operational charter it is suggested that practices of sanctioned exclusion will exemplify a state’s governance ethos. In this case, the business of exclusion will remain evidence enough as to the ability of government to engage or estrange members of their community. --Conference held Brisbane Convention and Exhibition Centre, Brisbane, Queensland, 14-17 August, 2005. An initiative of the United Nations and the Queensland Government.
Systematic screening of biorefinery technologies at the early stage of design (2012)

Improving technology readiness and government support have helped some forestry companies to continue to develop their biorefinery strategies over the past few years, including that for ethanol production in some cases. These developing technologies have been proven at various scales, and data required for their evaluation are typically scarce and uncertain. How can forestry companies select the “best” technology among the many options available to them, given this complex and uncertain landscape? The objective of this paper is to demonstrate the use of an early stage design tool for screening biorefinery technologies, using ethanol production as an example. A set of multidisciplinary criteria are defined that can be interpreted by a stakeholder panel, and calculated based on publically-available data. Then, the criteria are interpreted and weighed using multi-criteria decision-making (MCDM) analysis in order to make a global evaluation of technologies relative to each other, and identify those that should not be further considered.
Quantitative Trait Loci for Rice Heading Time in Koshihikari (2009)

摘要：
Plasma-membrane-anchored growth factor pro-amphiregulin binds A-type lamin and regulates global transcription (2008)

Amphiregulin (AR), a member of the EGF family, is synthesized as a type I transmembrane protein precursor (proAR) and expressed on the cell surface. Shedding of proAR yields a transmembrane-cytoplasmic fragment (AR-CTF), as well as a soluble AR. Here we demonstrate that the proAR-shedding stimuli trigger endocytosis of both AR-CTF and un-shed proAR. ProAR translocates from the plasma membrane to the inner nuclear membrane, whereas AR-CTF is translocated to the lysosome via retrograde membrane trafficking. Nuclear envelope localization of proAR involves truncation of the C-terminus, which subsequently activates the ER-retrieval signal. The truncated form of proAR interacts with A-type lamin and is retained at the inner nuclear membrane. Heterochromatin formation is then induced and global transcription is transiently suppressed. This study gives new insight into epigenetic chromatin organization in mammalian cells: a plasma-membrane-anchored growth factor is targeted to the inner nuclear membrane where it participates in dynamic chromatin organization and control of transcription.
Selection of mice for growth on high and low planes of nutrition (1960)

1. Two-way selection was applied to the growth of mice between 3 and 6 weeks of age when reared on a high plane of nutrition and, in another pair of lines, when reared on a low plane of nutrition. In each generation the growth of all four lines was measured on both high and low planes of nutrition. 2. Growth on the two planes of nutrition was treated as two different characters and the direct and correlated responses of each were estimated. The genetic correlation between the two characters was estimated from the responses of each of the four lines, and from the divergence between upward-and downward-selected lines. The different estimates should be the same if the theory of selection for correlated characters adequately accounts for the responses. Up to generation 7 the agreement was reasonably good, but in the later generations it was not. Four estimates of the genetic correlation up to generation 7 were: 0·75, 0·19, 0·66, 0·57. 3. There was asymmetry between the upward and downward responses, and the realized heritabilities changed over the course of the experiment; so also did the phenotypic variation. In all these respects the lines behaved differently. 4. The conclusions drawn from the final responses are summarized at the beginning of the Discussion. 5. The mice produced by selection for increased growth on low plane, but later reared on high plane, were compared with those produced by selection on high plane. Their growth was the same, but they were heavier, had less fat and more protein, and were better mothers.
Bit-serial systolic array implementation of a multilayer perceptron (1993)

The paper describes the implementation of a bit-serial systolic array architecture for a multilayer perceptron. It is shown that both the recall phase and learning phase can be mapped onto a similar systolic array structure, with minor differences. As a result, a combined systolic array structure is proposed for both the recall phase and the learning phase. The design is simulated using the FIRST silicon compiler to solve the exclusive OR problem, and then compared with a 32-bit floating-point simulation. The central element, multiply-and-accumulate operator was fabricated using a 1.2 μm double metal CMOS p-well process by ORBIT semiconductor, and found to perform satisfactorily. The required chips were implemented with the same technology, and performance parameters estimated. Furthermore, the performance of this architecture in solving the NETtalk problem is compared with other implementations.
Increased Circulating Levels of Matrix Metalloproteinase-2 and -9 in Women with the Polycystic Ovary Syndrome (2006)

Obese women with PCOS have elevated serum concentrations of MMP-2 and -9. It might be hypothesized that elevated MMP concentrations may be related to increased cardiovascular risk in PCOS and/or menstrual irregularities associated with this syndrome.
Dehydration reduces stroke volume and cardiac output during exercise because of impaired cardiac filling and venous return, not left ventricular function (2020)

Dehydration accrued during intense prolonged whole-body exercise in the heat compromises peripheral blood flow and cardiac output ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mover><mml:mi>Q</mml:mi><mml:mo>˙</mml:mo></mml:mover></mml:math> ). A markedly reduced stroke volume (SV) is a key feature of the dehydration-induced cardiovascular strain, but whether the lower output of the heart is mediated by peripheral or cardiac factors remains unknown. Therefore, we repeatedly quantified left ventricular (LV) volumes, LV mechanics (LV twist, a marker of systolic muscle function, and LV untwisting rate, an independent marker of LV muscle relaxation), left intra-ventricular pressure gradients, blood volume and peripheral blood flow during 2 hr of cycling in the heat with and without dehydration (DEH: 4.0 ± 0.2% body mass loss and EUH: euhydration control, respectively) in eight participants (three females and five males). While brachial and carotid blood flow, blood volume, SV, LV end-diastolic volume (LVEDV), cardiac filling time, systemic vascular conductance and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mover><mml:mi>Q</mml:mi><mml:mo>˙</mml:mo></mml:mover></mml:math> were reduced in DEH compared to EUH after 2 hr, LV twist and untwisting rate tended to be higher (p = .09 and .06, respectively) and intra-ventricular pressure gradients were not different between the two conditions (p = .22). Furthermore, LVEDV in DEH correlated strongly with blood volume (r = .995, p < .01), head and forearms beat volume (r = .98, p < .05), and diastolic LV filling time (r = .98, p < .05). These findings suggest that the decline in SV underpinning the blunted <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mover><mml:mi>Q</mml:mi><mml:mo>˙</mml:mo></mml:mover></mml:math> with exercise-induced dehydration is caused by compromised LV filling and venous return, but not intrinsic systolic or diastolic LV function.
Migrating an MVS mainframe application to a PC (2004)

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Hybridization Studies by Crossing and Protoplast Fusion within the Genus Schizosaccharomyces Lindner (1982)

Hybridization studies based on the use of crossing and the protoplast fusion technique revealed the relationship between the various taxa of the yeast genus Schizosaccharomyces Lindner. From a series of intra- and interspecific crosses as well as protoplast fusions, we concluded that a revision of the genus is required. Being interfertile, S. pombe and S. malidevorans have to be included in one species S. pombe. From the protoplast fusion results, this new taxon seems to be closely related to S. octosporus. The results obtained are discussed in connection with the characteristics of the low temperature spectra of the cytochromes.
Transdermal Clonidine Compared with Hydrochlorothiazide as Monotherapy in Elderly Hypertensive Males (1989)

Sixteen of 22 elderly male patients (aged 60-74 years) who had previously taken only hydrochlorothiazide 50 mg completed a study evaluating the safety, efficacy, and tolerability of 12-20 weeks of transdermal clonidine (Catapres TTS) as monotherapy for mild hypertension. Thirteen of the sixteen patients (81%) responded to transdermal clonidine which was begun after 28 days of placebo. Five patients discontinued transdermal clonidine therapy because of intolerable skin irritation, and one because of daytime fatigue. Clonidine caused none of the metabolic effects we observed with hydrochlorothiazide: no change in serum potassium, uric acid, cholesterol, or triglyceride. Eleven of the 22 patients (50%) who began the study experienced a skin reaction under the transdermal clonidine patch. The incidence of dry mouth and fatigue in patients using transdermal clonidine was dose-related and similar to reports of dry mouth and fatigue in patients taking oral clonidine tablets. Rebound hypertension occurred in one patient upon withdrawal of transdermal clonidine. There was no effect of transdermal clonidine or hydrochlorothiazide on cognitive function or emotional state tested with three questionnaires. Overall, transdermal clonidine, in various doses, was as effective as hydrochlorothiazide in elderly male hypertensive patients. The effectiveness of both was inversely proportional to the level of untreated blood pressure. The high incidence of skin reactions limited prolonged use of transdermal clonidine in our patients.
Development of a CFD Boundary Condition to Model Transient Vapor Absorption in the Respiratory Airways (2010)

The absorption of moderately and highly soluble vapors into the walls of the conducting airways was previously shown to be a transient process over the timescale of an inhalation cycle. However, a boundary condition to predict the transient wall absorption of vapors in CFD simulations does not exist. The objective of this study was to develop and test a boundary condition that can be used to predict the transient absorption of vapors in CFD simulations of transport in the respiratory airways. To develop the boundary condition, an analytical expression for the concentration of an absorbed vapor in an air-mucus-tissue-blood (AMTB) model of the respiratory wall was developed for transient and variable air-phase concentrations. Based on the analytical expression, a flux boundary condition was developed at the air-mucus interface as a function of the far-field air-phase concentration. The new transient boundary condition was then implemented to predict absorption in a realistic model of the extrathoracic nasal airways through the larynx (nasal-laryngeal geometry). The results of the AMTB wall model verified that absorption was highly time dependent over the timescale of an inhalation cycle (approximately 1-2 s). At 1 s, transient conditions resulted in approximately 2-3 times more uptake in tissue and 20-25 times less uptake in blood than steady state conditions for both acetaldehyde and benzene. Application of this boundary condition to computational fluid dynamics simulations of the nasal-laryngeal geometry showed, as expected, that transient absorption significantly affected total deposition fractions in the mucus, tissue, and blood. Moreover, transient absorption was also shown to significantly affect the local deposition patterns of acetaldehyde and benzene. In conclusion, it is recommended that future analyses of vapors in the conducting airways consider time-dependent wall absorption based on the transient flux boundary condition developed in this study. Alternatively, a steady state absorption condition may be applied in conjunction with correction factors determined from the AMTB wall model.
On superimposed training for channel estimation: performance analysis, training power allocation, and frame synchronization (2006)

Channel estimation for single-input multiple-output (SIMO) time-invariant channels using superimposed training has been recently considered by several authors. A periodic (nonrandom) training sequence is arithmetically added (superimposed) at a low power to the information sequence at the transmitter before modulation and transmission. In particular, in , the channel is estimated using only the first-order statistics of the data under a fixed power allocation to training and under the assumption that the superimposed training sequence at the receiver is time-synchronized with its transmitted counterpart (frame synchronization). In this paper, we remove these restrictions. We first present a performance analysis of the approach of to obtain a closed-form expression for the channel estimation variance. We then address the issue of superimposed training power allocation for complex Gaussian random (Rayleigh) channels. Using the developed channel estimation variance expression, we cast the power allocation problem as one of optimizing a signal-to-noise ratio for equalizer design. Finally, we propose a novel approach for frame synchronization. All the results are illustrated via simulation examples involving frequency-selective Rayleigh fading. Simulation comparisons with an existing approach to frame synchronization is also provided.
A Mixed-Potential Sensor Based on a Ce[sub 0.8]Gd[sub 0.2]O[sub 1.9] Electrolyte and Platinum and Gold Electrodes (2000)

A mixed‐potential sensor was constructed and its response to reducing gases in an oxygen containing stream was measured at T = 550 and 600°C. The sensor response was maximum for and negligible for methane; other gases followed the trend methane < propane < CO, propylene < hydrogen. The mixed potentials developed at the Au and Pt electrodes were also independently monitored with respect to Pt air‐reference electrodes. The mixed potential at the Au electrode was always higher (more negative) than that at the Pt electrode irrespective of the type of reducing gas used. The polarization curves of the two electrodes during oxygen reduction were also measured. These measurements revealed that the mixed potential at the electrodes was dependent on both the amount of electrochemical oxidation of reducing gas and the overpotential for oxygen reduction. While the response of the Pt electrode was found to be stable at both 600 and 550°C, the Au electrode had stability problems at 600°C due to the changing morphology of the gold film. © 2000 The Electrochemical Society. All rights reserved.