gebhart/patrepeval huggingface dataset:
Performance evaluation of ICN/CCN based service migration approach in virtualized LTE systems (2014)

The continuous growth in using mobile devices (e.g. smart phones, tablets, etc.) has increased the complexity in provisioning cellular network resources. Applying the cloud computing model in LTE (Long Term Evolution) systems could be a good solution to increase LTE's performance by building a shared distributed mobile network that can optimize the utilization of resources, minimize communication delays, and avoid bottlenecks. One of the most important concepts used in mobile networks is service continuity. Mobile users moving from one sub-network to another should be able to seamlessly continue to retrieve content and use services (e.g. video streaming, electronic games, VoIP, etc.) that they want. In this paper, the Information Centric Networking/Content Centric Networking (ICN/CCN) approach is proposed to be used as a solution for service continuity in virtualized LTE systems. By using NS3 simulation experiments it is shown that the introduced approach is able to satisfy the performance related service continuity requirements.
Analysis of Protein Purification Using Ion-Exchange Membranes (1999)

The performance of ion-exchange membranes for protein purification is analyzed using numerical solutions of different mathematical models. The models incorporate nonlinear sorption isotherms and mass-transfer coefficients based on either the overall or local solid-phase and liquid-phase driving forces. The numerical solutions are compared to analytical solutions which use overall mass-transfer coefficients only and, in general, are theoretically incorrect for nonlinear isotherms. The numerical solutions are fit to experimental breakthrough curves from the literature. The models allow the determination of the rate-controlling mass-transfer phenomena and solid-phase concentration, and prediction of the operating and membrane-design parameters needed to obtain sharp breakthrough curves.
Mechanism of <scp>d</scp> -Cycloserine Action: Alanine Racemase from <i>Escherichia coli</i> W (1972)

The antibiotic d-cycloserine is an effective inhibitor of alanine racemase. The lack of inhibition by l-cycloserine of alanine racemase from Staphylococcus aureus led Roze and Strominger to formulate the cycloserine hypothesis. This hypothesis states that d-cycloserine has the conformation required of the substrates on the enzyme surface and that l-cycloserine cannot have this conformation. Alanine racemase from Escherichia coli W has been examined to establish whether these observations are a general feature of all alanine racemases. The enzyme (molecular weight = 95,000) has Michaelis-Menten constants of 4.6 x 10(-4)m and 9.7 x 10(-4)m for d- and l-alanine, respectively. The ratio of V(max) in the d- to l-direction is 2.3. The equilibrium constant calculated from the Haldane relationship is 1.11 +/- 0.15. Both d- and l-cycloserine are competitive inhibitors with constants (K(i)) of 6.5 x 10(-4)m and 2.1 x 10(-3)m, respectively. The ratio of K(m)d-alanine to K(i)d-cycloserine is 0.71, and the ratio of K(m)l-alanine to K(i)l-cycloserine is 0.46. Since l-cycloserine is an effective inhibitor, it is concluded that the cycloserine hypothesis does not apply to the enzyme from E. coli W.
Extremely Low Resistance Non-Alloyed Ohmic Contacts to n-GaAs Using Compositionally Graded In<sub>x</sub>Ga<sub>1-x</sub>As Layers (1986)

Silicon doping in lattice-mismatched In x Ga 1- x As ( x =0, 0.2, 0.35, 0.65, 1.0) films grown on GaAs by MBE is studied. The maximum carrier concentration for In x Ga 1- x As is found to increase with the InAs mole fraction, x . Based on this result, the x dependence of the specific contact resistance, ρ c , for non-alloyed ohmic contacts to n-GaAs using compositionally graded In x Ga 1- x As layers is also investigated. It is found that ρ c decreases with increasing x for x ≤0.65, and an extremely low specific contact resistance of 5×10 -8 Ω·cm 2 is obtained with 1.5×10 19 cm -3 doped n + -In 0.65 Ga 0.35 As.
Reactivity of epoxy resin in dispersed dicyandiamide system and dynamic viscoelasticity of the resulting product (1986)

Abstract A study was made on the curing reaction, leading to a cross‐linked network, of bisphenol A diglycidyl either in a dispersed dicyandiamide (DICY) system containing benzyl dimethylamine accelerator and on the dynamic viscoelasticity of the resulting product as related to the DICY particle size (Ds), and compared with a dissolved DICY system. The curing reaction rate varied inversely with logarithmic Ds and directly with the total surface area of the DICY particles, and the finally attainable extent of reaction of the epoxide group decreased with increasing Ds. Activation energy ranged from 14 to 17 kcal/mole depending slightly on Ds. The dynamic viscoelasticity of the cured product was also affected greatly by Ds. Cured product from the system with a 3 μm DICY displayed only a primary transition peak around 180°C in plots of viscoelastic decrement as a function of temperature. With DICY of larger than 10 μm Ds, the number of transition peaks increased to two or three, with a primary peak, a secondary peak around 140μC, and a tertiary peak around 90μC. The relative height of the secondary or tertiary peak increased with increasing Ds. The reaction of the dissolved DICY system proceeded at much the same rate as the 25 μm Ds system, but yielded a cured product with viscoelasticity similar to that of the 3 μm Ds system.
Effect of N<sub>2</sub> Addition on Aluminum Alloy Etching by Electron Cyclotron Resonance Reactive Ion Etching and Magnetically Enhanced Reactive Ion Etching (1995)

Aluminum alloy etching is an important process in ultra-large-scale integration (ULSI) fabrication. We investigated the effect of N 2 addition to Cl 2 +BCl 3 gas mixture on aluminum-copper alloy etching by electron cyclotron resonance reactive ion etching (ECR-RIE) and magnetically enhanced reactive ion etching (MERIE). In ECR-RIE, N 2 addition was effective in suppressing residues and post-etch corrosion of aluminum alloy interconnects; on the other hand, in MERIE, N 2 addition promoted the formation of residues and post-etch corrosion. This difference is probably caused by BCl X + in plasma, because it was found by mass spectral analysis that N 2 addition increased the amount of BCl X + in plasma of ECR-RIE, but it decreased that in plasma of MERIE.
On effectiveness of GC in Java (2000)

We study the effectiveness of garbage collection (GC) algorithms by measuring the time difference between the actual collection time of an object and the potential earliest collection time for that object. Our ultimate goal is to use this study in order to develop static analysis techniques that can be used together with GC to allow earlier reclamation of objects. The results may also be used to pinpoint application source code that could be rewritten in a way that would allow more timely GC. Specifically, we compare the objects reachable from the root set to the ones that are actually used again. The idea is that GC could reclaim unused objects even if they are reachable from the root set. Thus, our experiments indicate a kind of upper bound on storage savings that could be achieved. We also try to characterize these objects in order to understand the potential benefits of various static analysis algorithms. The Java Virtual Machine (JVM) was instrumented to measure objects that are reachable, but not used again, and to characterize these objects. Experimental results are shown for the SPECjvm98 benchmark suite. The potential memory savings for these benchmarks range from 23% to 74%.
A double-blind trial of the clinical effects of pulsed electromagnetic fields in osteoarthritis. (1993)

The decreased pain and improved functional performance of treated patients suggests that this configuration of PEMF has potential as an effective method of improving symptoms in patients with OA. This method warrants further clinical investigation.
Twenty-five-year corrosion tests of 55% Al-Zn alloy coated steel sheet (1993)

Long-term atmospheric corrosion tests of steel sheet hot-dip coated with a series of aluminum-zinc alloy compositions were conducted in a wide range of environments. In a severe marine environment, coatings containing 44.6% or more aluminum lasted about three times as long as conventional galvanized with the same coating thickness. In moderate marine, rural, and industrial environments, coatings containing 44.6% or more aluminum remained intact after 25 years and have already lasted twice as long as conventional galvanized.
Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell (2013)

Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in the pancreatic islets of insulin-resistant mouse models and type 2 diabetic human subjects. Reduction of miR-184 promotes the expression of its target Argonaute2 (Ago2), a component of the microRNA-induced silencing complex. Moreover, restoration of miR-184 in leptin-deficient ob/ob mice decreased Ago2 and prevented compensatory β cell expansion. Loss of Ago2 during insulin resistance blocked β cell growth and relieved the regulation of miR-375-targeted genes, including the growth suppressor Cadm1. Lastly, administration of a ketogenic diet to ob/ob mice rescued insulin sensitivity and miR-184 expression and restored Ago2 and β cell mass. This study identifies the targeting of Ago2 by miR-184 as an essential component of the compensatory response to regulate proliferation according to insulin sensitivity.
Immobilized Enzymes and Cells as Practical Catalysts (1983)

Performance of enzymes and whole cells in commercial applications can often be dramatically improved by immobilization of the biocatalysts, for instance, by their covalent attachment to or adsorption on solid supports, entrapment in polymeric gels, encapsulation, and cross-linking. The effect of immobilization on enzymatic properties and stability of biocatalysts is considered. Applications of immobilized enzymes and cells in the chemical, pharmaceutical, and food industries, in clinical and chemical analyses, and in medicine, as well as probable future trends in enzyme technology are discussed.
Very High Performance d.c. Coupled MMIC FET Amplifiers (1990)

A new design approach for broadband d.c. coupled MMIC FET amplifier stages allowing substantial improvements as gain, bandwidth, noise, input matching and stability over the state of the art solutions is described. Design and performances of two MMIC amplifiers accordingly developed are reported.
Savaric de Mauléon, Baron and Troubadour (1939)

Savaric de Mauléon, Baron and Troubadour Get access Notes and Queries, Volume 176, Issue 10, 11 March 1939, Pages 179–180, https://doi.org/10.1093/nq/176.10.179f Published: 11 March 1939
Role of Endogenous Bradykinin in Human Coronary Vasomotor Control (1995)

The results of this study demonstrate for the first time a role for endogenous bradykinin in mediating normal vasomotor responses in resistance and epicardial coronary vessels under basal and flow-stimulated conditions in the human coronary circulation.
Low-voltage BICMOS and vertical OTA (1992)

A linear BICMOS operational transconductance amplifier (OTA) with low voltage supply requirements is presented. Two versions of this circuit using stacked and folded BICMOS composite transistors are discussed. Simulations and experimental results using transistor arrays are shown that verify the operating principle of the proposed structures.
Self‐Organized Cell Outage Detection Architecture and Approach for 5G H‐CRAN (2018)

An attractive architecture called heterogeneous cloud radio access networks (H‐CRAN) becomes one of the important components of 5G networks, which can provide ubiquitous high‐bandwidth services with flexible network construction. However, massive access nodes increase the risk of cell outages, leading to negative impact on user‐perceived QoS (Quality of Service) and QoE (Quality of Experience). Thus, cell outage management (COM) became a key function proposed in SON (Self‐Organized Networks) use cases. Based on COM, cell outage detection (COD) will be resolved before cell outage compensation (COC). Currently few studies concentrate on COD for 5G H‐CRAN, and we propose self‐organized COD architecture and approach for it. We firstly summarize current COD solutions for LTE/LTE‐A HetNets and then introduce self‐organized architecture and approach suitable for H‐CRAN, which includes COD architecture and procedures, and corresponding key technologies for it. Based on the architecture, we take a use case with handover data analysis using modified LOF (Local Outlier Factor) detection approach to detect outage for different kinds of cells in H‐CRAN. Results show that the proposed approach can identify the outage cell effectively.
Hysteretic current–voltage characteristics and resistance switching at an epitaxial oxide Schottky junction SrRuO3∕SrTi0.99Nb0.01O3 (2004)

Transport properties have been studied for a perovskite heterojunction consisting of SrRuO3 (SRO) film epitaxially grown on SrTi0.99Nb0.01O3 (Nb:STO) substrate. The SRO/Nb:STO interface exhibits rectifying current–voltage (I–V) characteristics agreeing with those of a Schottky junction composed of a deep work-function metal (SRO) and an n-type semiconductor (Nb:STO). A hysteresis appears in the I–V characteristics, where high resistance and low resistance states are induced by reverse and forward bias stresses, respectively. The resistance switching is also triggered by applying short voltage pulses of 1μs–10ms duration.
Edge detection using a Hopfield neural network (1994)

The Hopfield neural network has been widely applied in many areas. Is highly interconnected structure of neurons is not only very effective in computational complexity but also very fault tolerant. Such neural networks have been used as analog computational networks for solving optimization problems. The low-level image processing of edge detection can also be regarded as an optimization problem. This paper presents an edge detection algorithm using a Hopfield neural network. This algorithm utilizes a concept that is different from conventional differentiation operators, such as the Sobel and Laplacian. In this algorithm, an image is mapped to a Hopfield neural network, which is completely depicted by an energy function. In other words, an image is described by a set of interconnected neurons. Every pixel in the image is represented by a neuron, which is connected to all other neurons but not to itself. The weight of connection between two neurons is described as a function of the contrast of gray-level values and the distance between the two pixels. The initial state of each neuron represents the normalized gray-level value of the corresponding pixel in the original image. As a result of Hopfield-network analysis, neuron states are modified till convergence. Even though the neuron states are analog, they are close to 1.0 in all regions except edges, where the corresponding neurons have near-0.0 state values. A robust threshold on the output level of the converged network can be easily set up at 0.5 to extract edges.
Systemic Drug Treatment for Chronic Musculoskeletal Pain (2001)

For chronic pain, opioid analgesics provide benefit for up to 9 weeks (level 2). For chronic low back pain, the evidence shows that various types of nonsteroidal antiinflammatory drugs are equally effective or ineffective, and that antidepressants provide no benefit in the short to intermediate term (level 2). Muscle relaxants showed limited effectiveness (level 3) for chronic neck pain and for chronic low back pain for up to 4 weeks. For fibromyalgia, there is limited evidence (level 3) of the effectiveness of amitryptiline, ondansetron, zoldipem, or growth hormone, and evidence of no effectiveness for nonsteroidal anti-inflammatory drugs, malic acid with magnesium, calcitonin injections, or s-adenyl-L-methionine. For temporomandibular pain, oral sumatriptan is not effective (level 2). The remaining evidence was inadequate (level 4a) or contradictory (level 4b).
TNF-alpha potentiation of the lymphokine-activated killer response of murine thymus cells. (1994)

The role of tumor necrosis factor (TNF-alpha) on in vitro generation of lymphokine-activated killer (LAK) cells from murine thymocytes was investigated and compared to that on generation of LAK from splenocytes. TNF-alpha increased the potential of interleukin-2 (IL-2) at suboptimal concentrations to generate LAK activity in thymocytes even more than in splenocytes. In parallel, augmented [3H]thymidine uptake by thymocytes and splenocytes was seen. However, no net increase in viable cell number was observed. LAK effector cells from TNF-alpha plus IL-2 cultures responded with an increased [3H]thymidine uptake to restimulation by IL-2 alone. These results suggest that TNF-alpha + IL-2 may be inducing the expansion of a small subset of cells. NK1.1+ cells are a very minor subset of thymocytes, nevertheless phenotype analysis showed that in thymocytes, IL-2 + TNF-alpha generates NK1.1+ CD8- LAK effectors in contrast to NK1.1- CD8+ cells found with IL-2 alone. This result is consistent with the finding in the proliferation studies. The fact that thymocytes are stimulated by the TNF-alpha + IL-2 combination to proliferate as well as to develop a phenotypically distinct effector supports the role of TNF-alpha in intra- and extrathymic regulation.
Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model (2005)

HCN4 is the dominant subunit in canine sinoatrial node and RA; strong sinus node HCN expression likely contributes to its pacemaker function; downregulation of HCN4 and HCN2 expression contribute to CHF-induced sinus node dysfunction; and upregulation of atrial HCN4 may help to promote atrial arrhythmia formation. These findings provide novel information about the molecular basis of normal and disease-related impairments of cardiac impulse formation.
Clinical Pharmacokinetics of Amonafide (NSC 308847) in 62 Patients (1996)

Amonafide (A) demonstrates dose-related increases in area under the curve (AUC) and Cmax values. Total body clearance for A (ranging from 44.2 to 53.8 L/hr/m2) is relatively constant within the dosing range of this study. The dose-related increase of AUC was also observed for the two identified metabolites, acetylamonafide (AA) and noramonafide (NA). A and NA plasma data could be described by a four-compartmental model (two compartments for A, one compartment each for NA and AA). The fitting for NA was poor owing to its low plasma concentration. The terminal half-lives for A, NA, and AA were in the range of 3-6 hr. No cumulative accumulation of parent compound or metabolites was detected after daily administration, The concentrations of A, NA, and AA 24 hr after dosing were either below or very close to the quantitative limits of the assay. Polymorphic disposition of A was confirmed by a frequency distribution of AUC value versus dose plot.
Immunoseparation method for measuring low-density lipoprotein cholesterol directly from serum evaluated. (1995)

Low-density lipoprotein (LDL) cholesterol can not be calculated from other lipid measurements when samples are obtained from nonfasting individuals or when triglycerides are > or = 4.0 g/L. We have evaluated a direct LDL cholesterol assay for analyzing 115 fresh serum samples obtained from fasting and nonfasting dyslipidemic patients with triglycerides < or = 35.85 g/L, who were receiving diet and (or) drug treatments. Results were highly correlated with those by ultracentrifugation (r = 0.97), with a mean/median bias of -2.9%/0.7% (-0.001/0.010 g/L) and an absolute bias of 9.5%/6.4% (0.119/0.090 g/L). The assay correctly classified LDL cholesterol concentrations < 1.30 g/L 81% of the time, 1.30-1.60 g/L 76% of the time, and > or = 1.60 g/L 94% of the time. Precision studies provided within- and between-run CVs in the range of 1.2-3.8% and 2.0-5.1%, respectively. Our data indicate that this assay is an accurate method for measuring LDLC directly from fresh serum obtained from fasting or nonfasting subjects with a wide range of triglyceride values.
Multichannel RLS algorithms and FTF algorithms for active noise control and sound reproduction systems (1999)

In the fields of active noise control (ANC) and transaural sound reproduction (TSR), multichannel FIR adaptive filters are extensively used. For the learning of such FIR adaptive filters, recursive-least-squares (RLS) algorithms are known to typically produce a faster convergence speed than stochastic gradient descent techniques, such as the basic least-mean-squares (LMS) algorithm or even the fast convergence Newton-LMS, gradient-adaptive-lattice (GAL) LMS and discrete-cosine-transform (DCT) LMS algorithms. In this presentation, multichannel RLS algorithms and multichannel fast-transversal-filter (FTF) algorithms are introduced, with the structures of some stochastic gradient descent algorithms used in ANC: the filtered-x LMS, the adjoint-LMS and the modified filtered-x LMS. The new algorithms can be used in ANC systems or for the deconvolution of sounds in TSR systems. Also, heuristic techniques are introduced, to compensate for the potential ill-conditioning of the correlation matrix in ANC or TSR systems, and for the potential numerical instability of the multichannel FTF-based algorithms. Simulations of ANC and TSR systems will compare the performance of the different multichannel LMS, RLS, and FTF-based algorithms.
Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice (2011)

Adipocyte and β-cell dysfunction and macrophage-related chronic inflammation are critical for the development of obesity-related insulin resistance and type 2 diabetes mellitus (T2DM), which can be negatively regulated by Tregs. Our previous studies and those of others have shown that activation of γ-aminobutyric acid (GABA) receptors inhibits inflammation in mice. However, whether GABA could modulate high fat diet (HFD)-induced obesity, glucose intolerance and insulin resistance has not been explored. Here, we show that although oral treatment with GABA does not affect water and food consumption it inhibits the HFD-induced gain in body weights in C57BL/6 mice. Furthermore, oral treatment with GABA significantly reduced the concentrations of fasting blood glucose, and improved glucose tolerance and insulin sensitivity in the HFD-fed mice. More importantly, after the onset of obesity and T2DM, oral treatment with GABA inhibited the continual HFD-induced gain in body weights, reduced the concentrations of fasting blood glucose and improved glucose tolerance and insulin sensitivity in mice. In addition, oral treatment with GABA reduced the epididymal fat mass, adipocyte size, and the frequency of macrophage infiltrates in the adipose tissues of HFD-fed mice. Notably, oral treatment with GABA significantly increased the frequency of CD4(+)Foxp3(+) Tregs in mice. Collectively, our data indicated that activation of peripheral GABA receptors inhibited the HFD-induced glucose intolerance, insulin resistance, and obesity by inhibiting obesity-related inflammation and up-regulating Treg responses in vivo. Given that GABA is safe for human consumption, activators of GABA receptors may be valuable for the prevention of obesity and intervention of T2DM in the clinic.