gebhart/patrepeval huggingface dataset:
Features of the amorphous-crystalline structure of UHMWPE (2011)

To reveal the features of the structure of UHMWPE that depend on the catalytic system used for synthesis, a comparative study of the sets of laboratory and commercial powders of UHMWPE synthesized on different catalysts in the slurry process under different conditions is conducted. This study includes the use of various modern physical methods, such as transmission and scanning electron microscopy, X-ray analysis, Raman scattering spectroscopy, differential scanning calorimetry, nuclear magnetic resonance, and thermoluminescence. All nascent particles are shown to have a complex hierarchical structure. In all reactor powders, the elementary structural unit is crystalline lamellas, whose dimensions and mutual orientation are dependent on the type of catalytic system. In the synthesis on the supported catalysts, the character of the formed structure depends on the characteristics of the substrate. During the breakdown of the substrate in the course of the synthesis, fibrils form. The colloidal dimensions of the catalyst particles are responsible for a more uniform lamellar structure of the reactor powders. The conformational composition of the segments of molecules in the interlamellar regions of the reactor powders is characterized.
Leveraging parallelism for multi-dimensional packetclassification on software routers (2010)

We present a software-based solution to the multi-dimensional packet classification problem which can operate at high line speeds, e.g., in excess of 10 Gbps, using high-end multi-core desktop platforms available today. Our solution, called Storm, leverages a common notion that a subset of rules are likely to be popular over short durations of time. By identifying a suitable set of popular rules one can significantly speed up existing software-based classification algorithms. A key aspect of our design is in partitioning processor resources into various relevant tasks, such as continuously computing the popular rules based on a sampled subset of traffic, fast classification for traffic that matches popular rules, dealing with packets that do not match the most popular rules, and traffic sampling. Our results show that by using a single 8-core Xeon processor desktop platform, it is possible to sustain classification rates of more than 15 Gbps for representative rule sets of size in excess of 5-dimensional 9000 rules, with no packet losses. This performance is significantly superior to a 8-way implementation of a state-of-the-art packet classification software system running on the same 8-core machine. Therefore, we believe that our design of packet classification functions can be a useful classification building block for RouteBricks-style designs, where a core router might be constructed as a mesh of regular desktop machines.
Volatiles on Mars (2003)

Compared to Earth’s atmosphere, Mars has a thin CO2-rich atmosphere with a surface pressure of about 700 Pa. When normalized to planetary mass (mass of Mars is 10.7% of that of Earth), the abundance of volatiles on Mars is about 0.07% to 6% of that on Earth (when CO2 in terrestrial carbonates is included). Is the depletion of volatiles on Mars a primary feature (because less volatiles accreted on Mars than on Earth), or a secondary feature (due to lower degree of degassing or due to gas escape to outer space)? In this contribution, I outline a simple model for volatile budgets of Mars, and implications for water on Mars.
Regulation of epithelial permeability by the actin cytoskeleton (2011)

The actin cytoskeleton is a dynamic structure necessary for cell and tissue organization, including the maintenance of epithelial barriers. The epithelial barrier regulates the movement of ions, macromolecules, immune cells, and pathogens, and is thus essential for normal organ function. Disruption in the epithelial barrier has been shown to coincide with alterations of the actin cytoskeleton in several disease states. These disruptions primarily manifest as increased movement through the paracellular space, which is normally regulated by tight junctions (TJ). Despite extensive research demonstrating a direct link between the actin cytoskeleton and epithelial permeability, our understanding of the physiological mechanisms that link permeability and tight junction structure are still limited. In this review, we explore the role of the actin cytoskeleton at TJ and present several areas for future study.
Synthesis of syndiotactic poly-1,2-(4-methyl-1,3-pentadiene) (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of syndiotactic poly-1,2-(4-methyl-1,3-pentadiene)Adolfo Zambelli, Paolo Ammendola, and Antonio ProtoCite this: Macromolecules 1989, 22, 5, 2126–2128Publication Date (Print):May 1, 1989Publication History Published online1 May 2002Published inissue 1 May 1989https://pubs.acs.org/doi/10.1021/ma00195a020https://doi.org/10.1021/ma00195a020research-articleACS PublicationsRequest reuse permissionsArticle Views291Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
New role for nuclear hormone receptors and coactivators in regulation of BRCA1-mediated DNA repair in breast cancer cell lines (2005)

The present study proposes a new mechanism by which ER and RAR regulate BRCA1-mediated DNA repair by means of CBP.
Heavy chain ferritin acts as an anti‐apoptotic gene that protects livers from ischemia‐reperfusion injury (2003)

Heme oxygenase-1 (HO-1) is induced under a variety of pro-oxidant conditions such as those associated with ischemia-reperfusion injury (IRI) of transplanted organs. HO-1 cleaves the heme porphyrin ring releasing Fe2+, which induces the expression of the Fe2+ sequestering protein ferritin. By limiting the ability of Fe2+ to participate in the generation of free radicals through the Fenton reaction, ferritin acts as an anti-oxidant. We have previously shown that HO-1 protects transplanted organs from IRI. We have linked this protective effect with the anti-apoptotic action of HO-1. Whether the iron-binding properties of ferritin contributed to the protective effect of HO-1 was not clear. We now report that recombinant adenovirus mediated overexpression of the ferritin heavy chain (H-ferritin) gene protects rat livers from IRI and prevents hepatocellular damage upon transplantation into syngeneic recipients. The protective effect of H-ferritin is associated with the inhibition of endothelial cell and hepatocyte apoptosis in vivo. H-ferritin protects cultured endothelial cells from apoptosis induced by a variety of stimuli. These findings unveil the anti-apoptotic function of H-ferritin and suggest that H-ferritin can be used in a therapeutic manner to prevent liver IRI and thus maximize the organ donor pool used for transplantation.
Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles (2010)

Nuclear receptors (NRs) are ligand dependent transcriptional factors and play a key role in reproduction, development, and homeostasis of organism. NRs are potential targets for treatment of cancer and other diseases such as inflammatory diseases, and diabetes. In this study, we present a comprehensive library of pocket conformational ensembles of thirteen human nuclear receptors (NRs), and test the ability of these ensembles to recognize their ligands in virtual screening, as well as predict their binding geometry, functional type, and relative binding affinity. 157 known NR modulators and 66 structures were used as a benchmark. Our pocket ensemble library correctly predicted the ligand binding poses in 94% of the cases. The models were also highly selective for the active ligands in virtual screening, with the areas under the ROC curves ranging from 82 to a remarkable 99%. Using the computationally determined receptor-specific binding energy offsets, we showed that the ensembles can be used for predicting selectivity profiles of NR ligands. Our results evaluate and demonstrate the advantages of using receptor ensembles for compound docking, screening, and profiling.
Optimization Of The Deblocking Filter In H.264 Codec For Real Time Implementation (2006)

Blocking artifacts are visible in the decoded frames of most video coding standards at low bit rate coding. Latest video coding standard H.264/AVC uses an in-loop deblocking filter to remove the blocking artifacts. The main drawback of this filter is its high implementation complexity. In this paper, we propose an in-loop deblocking filter to remove the blocking artifacts. In the proposed method, the maximum and minimum values among the six pixels across an edge are computed to decide whether the pixels of the block should be filtered or not. For intra frames, again the block is classified as smooth or mildly textured region. Depending on the classification of the block, the appropriate filter is applied to that block. The main advantage of the proposed method is its low complexity compared to JM 9.8 (H.264 software). A performance comparison of the proposed method and the current method is presented
Electronic structure of silicon oxynitride: <i>Ab-initio</i> and experimental study, comparison with silicon nitride (2011)

Amorphous silicon oxide SiO2, silicon nitride Si3N4, and silicon oxynitride SiOxNy are three key dielectrics in silicon devices. Implementation of nitrided oxide (oxynitride SiOxNy) as a gate dielectric in metal-oxide-semiconductor field effect transistors has been shown to significantly improve the reliability and lifetime of devices. Also, amorphous oxynitride is used as a tunnel dielectric in nonvolatile flash memory devices. The present paper is devoted to the experimental and theoretical study of silicon oxynitride electronic structure. The ionic formula of crystalline Si2N2O is deduced from the first principles. Effective masses of charge carriers in Si2N2O are calculated and compared with experimental data on tunnel injection in amorphous SiNxOy samples. Also experimental x-ray absorption and emission spectra are compared with the theoretically calculated ones.
Identification of Endogenous Sympathetic Neuron Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP): Depolarization Regulates Production and Secretion through Induction of Multiple Propeptide Transcripts (1997)

The vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide (PACAP)/secretin/glucagon family of peptides displays numerous physiological roles in autonomic nervous system development and function. The regulated endogenous production and release of PACAP peptides in sympathetic neurons of the superior cervical ganglion (SCG) was investigated. The two posttranslationally processed forms of PACAP, PACAP27 and PACAP38, were identified in rat adult, neonatal, and cultured SCG neurons. PACAP38 levels were approximately 5-10 fmol/adult SCG and approximately 2 fmol/neonatal SCG; PACAP27 levels were comparable. The authenticity of peptide immunoreactivity in these tissues was verified by coelution with synthetic PACAP in reverse-phase HPLC analysis. Reverse transcription-PCR and sequence-specific hybridization revealed PACAP mRNA in adult, neonatal, and cultured SCG neurons; in situ hybridization histochemistry and immunocytochemistry localized the PACAP peptide and proPACAP mRNA to a subset of the SCG neuronal population. Basal and stimulated release of endogenous PACAP38 from cultured sympathetic neurons was established, suggesting that these peptides may function as signaling molecules at target tissues. Chronic depolarization with 40 mM potassium stimulated the PACAP secretory rate 10- to 20-fold, with concomitant increases in cellular PACAP peptide and mRNA levels. When examined using Northern analysis, depolarizing conditions not only stimulated the 2.2 kb form of PACAP mRNA, but also induced the expression of a shortened, 0.9 kb, transcript. Further reverse-transcription PCR analysis demonstrated that this smaller transcript was not identical to the unique testicular message. These studies identify PACAP38 and PACAP27 as regulated endogenous releasable peptides contributing to the functional diversity and phenotypic plasticity of the sympathetic nervous system.
Adaptation of<i>Escherichia coli</i>to high osmolarity environments: Osmoregulation of the high-affinity glycine betaine transport system ProU (1994)

A sudden increase in the osmolarity of the environment is highly detrimental to the growth and survival of Escherichia coli and Salmonella typhimurium since it triggers a rapid efflux of water from the cell, resulting in a decreased turgor. Changes in the external osmolarity must therefore be sensed by the microorganisms and this information must be converted into an adaptation process that aims at the restoration of turgor. The physiological reaction of the cell to the changing environmental condition is a highly coordinated process. Loss of turgor triggers a rapid influx of K+ ions into the cell via specific transporters and the concomitant synthesis of counterions, such as glutamate. The increased intracellular concentration of K(+)-glutamate allows the adaptation of the cell to environments of moderately high osmolarities. At high osmolarity, K(+)-glutamate is insufficient to ensure cell growth, and the bacteria therefore replace the accumulated K+ ions with compounds that are less deleterious for the cell's physiology. These compatible solutes include polyoles such as trehalose, amino acids such as proline, and methyl-amines such as glycine betaine. One of the most important compatible solutes for bacteria is glycine betaine. This potent osmoprotectant is widespread in nature, and its intracellular accumulation is achieved through uptake from the environment or synthesis from its precursor choline. In this overview, we discuss the properties of the high-affinity glycine betaine transport system ProU and the osmotic regulation of its structural genes.
Industry Patents (2008)

Plastics Engineering is the official publication of the Society of Plastics Engineers (SPE). We provide plastics professionals with a wealth of information about machinery, technological advances, materials innovations, sustainability, and more.
The Relationship between Nano Crystallite Structure and Internal Stress in Ni Coatings Electrodeposited by Watts Bath Electrolyte Mixed with Supercritical CO<sub>2</sub> (2012)

In this study, the internal stress of Ni coating electroplated in the supercritical-CO2 (Sc-CO2) mixed Watts bath was investigated with a focus on the effects of plating parameters and additives. Both the internal stresses of the Ni coatings and their corresponding microstructures were examined. A relationship is found that the internal stress of the Ni coating was inversely proportional to its grain size and the Ni{200}/Ni{111} peak fraction in the measured X-ray diffraction pattern. The smaller grain size, accompanied with higher Ni{111} intensity, resulted in the higher internal stress of the coating, and vice versa. A proposed theoretical model, which took both the grain size and preferred crystalline orientation into account, correlated closely with experimental results in the internal stress. As a result, the presence of surfactant in the Sc-CO2 electrolyte increased the internal stress of Ni coating. However, a reduction of internal stress is made possible by varying four factors: the raising of current density, the increasing of plating temperature, the lowering of plating pressure, and the addition of saccharin into electrolyte. A comparison to the internal stress of Ni coatings plated by the conventional method was also discussed in this study.
Solutions for printing sub-100-nm contacts with ArF (2002)

This study assesses the various approaches to printing contacts in the sub 100nm regime using 193nm. Traditional techniques are analyzed along with the use of tri-tone contacts and pupil filtering. Approaches using attPSM masks looks promising down to pitches of 300nm. Below this, assist features may be needed to prevent residual artifacts due to sidelobes. For pitches > 400nm the use of tri-tone masks show a significant improvement in process latitude and ease of overlapping process windows. The pupil filter solution does not seem provide any significant improvement as compared to other solutions with the exception that it provides the lower MEF. Realization of this solution will increase machine complexity and will possibly impact throughput, especially if using transmission filters. However, pupil filtering can be an option for isolated contact layers that are printed with binary masks. We find that the process and enhancement techniques to print a dense contacts and isolated contacts to be vastly different. This may require a split into two exposures if an extensive pitch range is needed.
Nonperturbative QCD simulations with<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mn>2</mml:mn><mml:mo>+</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:math>flavors of improved staggered quarks (2010)

Dramatic progress has been made over the last decade in the numerical study of quantum chromodynamics (QCD) through the use of improved formulations of QCD on the lattice (improved actions), the development of new algorithms, and the rapid increase in computing power available to lattice gauge theorists. In this article simulations of full QCD are described using the improved staggered quark formalism, ``asqtad'' fermions. These simulations were carried out with two degenerate flavors of light quarks (up and down) and with one heavier flavor, the strange quark. Several light quark masses, down to about three times the physical light quark mass, and six lattice spacings have been used. These enable controlled continuum and chiral extrapolations of many low energy QCD observables. The improved staggered formalism is reviewed, emphasizing both advantages and drawbacks. In particular, the procedure for removing unwanted staggered species in the continuum limit is reviewed. Then the asqtad lattice ensembles created by the MILC Collaboration are described. All MILC lattice ensembles are publicly available, and they have been used extensively by a number of lattice gauge theory groups. The physics results obtained with them are reviewed, and the impact of these results on phenomenology is discussed. Topics include the heavy quark potential, spectrum of light hadrons, quark masses, decay constants of light and heavy-light pseudoscalar mesons, semileptonic form factors, nucleon structure, scattering lengths, and more.
Design Considerations for Small Signal Modeling of DC-DC Converters Using Inductor DCR Current Sensing Under Time Constants Mismatch Conditions (2007)

This paper compares advantages and disadvantages of several commonly used current sensing methods such as dedicated sense resistor sensing, MOSFET Rds(on) current sensing, and inductor DC resistance (DCR) current sensing. Among these current sense methods, inductor DCR current sense that shows more advantages over other current sensing methods is chosen for analysis. The time constants mismatch issue between the time constant made by the current sensing RC network and the one formed with output inductor and its DC resistance is addressed in this paper. And an unified small signal modeling of a buck converter using inductor DCR current sensing with matched and mismatched time constants is presented, and the modeling has been verified experimentally.
Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand (2010)

When administered orally at 1 ml/5 kg bodyweight, derquantel-abamectin is highly effective for the treatment of gastrointestinal nematodes in sheep, including populations of strongyles and Nematodirus sp. with resistance to one or more single- or dual-active anthelmintics. Derquantel-abamectin presents sheep producers with a unique opportunity to introduce a new class of anthelmintic to their nematode control programmes, with the added benefits offered by a combination anthelmintic.
Novel carbonaceous materials for lithium secondary batteries (1997)

Carbonaceous materials have been synthesized using pillared clays (PILCs) as templates. The PILC was loaded with organic materials such as pyrene in the liquid and vapor phase, styrene in the vapor phase, trioxane, ethylene and propylene. The samples were then pyrolyzed at 700 C in an inert atmosphere, followed by dissolution of the inorganic template by conventional demineralization methods. X-ray powder diffraction of the carbons showed broad d{sub 002} peaks in the diffraction pattern, indicative of a disordered or turbostratic system. N{sub 2} BET surface areas of the carbonaceous materials range from 10 to 100 m{sup 2}/g. There is some microporosity (r < 1 nm) in the highest surface area carbons. Most of the surface area, however, comes from a mixture of micro and mesopores with radii of 2--5 nm. Electrochemical studies were performed on these carbons. Button cells were fabricated with capacity- limiting carbon pellets electrodes as the cathode a/nd metallic lithium foil as the anode. Large reversible capacities (up to 850 mAh/g) were achieved for most of the samples. The irreversible capacity loss was less than 180 mAh/g after the first cycle, suggesting that these types of carbon materials are very stable to lithium insertion and de-insertion reactions.
Functionality defense by heterogeneity: a new paradigm for securing systems (2004)

The human race has evolved and thrived despite perpetually being attacked by different kinds of viruses, infections, diseases, etc. The body's natural immune system and self healing mechanism as well as the assisted healing systems in human communities has played a major role in this accomplishment. This model has served as an inspiration for the development of a new paradigm for security that we have proposed in this paper. While most security systems focus on defense of a single machine or a cluster of machines we have taken a radically different approach to security. We look at defense of functionalities rather than systems in the traditional sense. In this paper, we propose a new way to look at security called the functionality (such as e-mail server, Web services server, etc) defense by heterogeneity. Further we present an analysis, architecture and an algorithm for defending functionality.
Evaluation of interaural signal differences. (1982)

A model of binaural signal processing is discussed which is based on a running interaural cross-correlation mechanism in frequency bands. A pattern of a hypothetical "binaural neural activity distribution" is derived from the ear signals. It is assumed that the binaural activity patterns are evaluated by a central pattern-recognition processor, which extracts certain cues to form the spatial attributes of the auditory events. The model is applied to sound fields in rooms to explain a special kind of spatial impression on the listener which can be described as "spaciousness".