gebhart/patrepeval huggingface dataset:
Non‐invasive cryolipolysis™ for subcutaneous fat reduction does not affect serum lipid levels or liver function tests (2009)

Cryolipolysis, when used for reduction of subcutaneous flank fat, is not associated with changes in serum lipids or liver test results.
Development and treatment of fresh lung carcinoma after successful lobectomy. (1966)

A close follow-up of all patients treated surgically for lung carcinoma has been carried out. The follow-up was designed to give as much informa- tion as possible on the cause of death following operation, particularly over the long term. During this study it became clear that many patients developed fresh evidence, primarily radiological, of lung carcinoma at varying times after opera- tion. This appeared to be more frequent than the literature suggested and to be a problem of sufficient size to consider the possibility of further operative treatment in an attempt to arrest the progress of the disease. This and other aspects considered in this paper have already been fully discussed by Hughes and Blades (1961) in their report.
Myosin isoenzymes in human hypertrophic hearts. Shift in atrial myosin heavy chains and in ventricular myosin light chains (1984)

The myosin light chain complement and proteolytic peptide patterns of myosin heavy chains were studied by two-dimensional and one-dimensional electrophoretic techniques respectively, in a total of 57 samples from ventricular and atrial tissues of normal and hypertrophied human hearts. Hypertrophies were classified haemodynamically as due to pressure-overload and volume-overload. In addition to the occurrence of ventricular light chains in hypertrophied atria we also observed the atrial light chain-1 (ALC-1) in hypertrophied ventricular tissues. On average over 6% of total light-chain-1 comprised ALC-1 in pressure-overloaded ventricles and around 3% in volume-overloaded ventricles. In single cases of pressure-overload ALC-1 amounted up to over 20% of total light chain-1. With regard to the myosin heavy chains limited digestion by two different proteinases produced over 200 clearly resoluble peptides. The absence of any detectable differences in the peptide patterns between myosin heavy chains from normal and hypertrophic tissues of left or right ventricle is in line with the findings of J. J. Schier and R. S. Adelstein (J Clin Invest 1982; 69: 816-825). In atrial tissues however, reproducible qualitative differences in the peptide patterns indicated that during hypertrophy a different type of myosin heavy chains becomes expressed. No differences were seen between the myosin heavy chains from normal left and right atria.
What are they doing? : Collective activity classification using spatio-temporal relationship among people (2009)

In this paper we present a new framework for pedestrian action categorization. Our method enables the classification of actions whose semantic can be only analyzed by looking at the collective behavior of pedestrians in the scene. Examples of these actions are waiting by a street intersection versus standing in a queue. To that end, we exploit the spatial distribution of pedestrians in the scene as well as their pose and motion for achieving robust action classification. Our proposed solution employs extended Kalman filtering for tracking of detected pedestrians in 2D 1/2 scene coordinates as well as camera parameter and horizon estimation for tracker filtering and stabilization. We present a local spatio-temporal descriptor effective in capturing the spatial distribution of pedestrians over time as well as their pose. This descriptor captures pedestrian activity while requiring no high level scene understanding. Our work is tested against highly challenging real world pedestrian video sequences captured by low resolution hand held cameras. Experimental results on a 5-class action dataset indicate that our solution: i) is effective in classifying collective pedestrian activities; ii) is tolerant to challenging real world conditions such as variation in illumination, scale, viewpoint as well as partial occlusion and background motion; iii) outperforms state-of-the art action classification techniques.
Hairstyle Construction from Raw Surface Data (2006)

We present a novel approach to the problem of hairstyle construction from raw surface data such as the ones obtained from surface scans. Our approach is based on a shape matching algorithm that fits individual hair fibers into a given volume according to a set of boundary conditions and additional hair density information. Our method employs a mechanical rod model based on the special theory of Cosserat rods. Such models can efficiently be used to simulate the deformation of individual fibers in subsequent manipulation steps.
Generation of CD4+CD25+ Regulatory T Cells from Autoreactive T Cells Simultaneously with Their Negative Selection in the Thymus and from Nonautoreactive T Cells by Endogenous TCR Expression (2002)

Normal T cell repertoire contains regulatory T cells that control autoimmune responses in the periphery. One recent study demonstrated that CD4(+)CD25(+) T cells were generated from autoreactive T cells without negative selection. However, it is unclear whether, in general, positive selection and negative selection of autoreactive T cells are mutually exclusive processes in the thymus. To investigate the ontogeny of CD4(+)CD25(+) regulatory T cells, neo-autoantigen-bearing transgenic mice expressing chicken egg OVA systemically in the nuclei (Ld-nOVA) were crossed with transgenic mice expressing an OVA-specific TCR (DO11.10). Ld-nOVA x DO11.10 mice had increased numbers of CD4(+)CD25(+) regulatory T cells in the thymus and the periphery despite clonal deletion. In Ld-nOVA x DO11.10 mice, T cells expressing endogenous TCR alpha beta chains were CD4(+)CD25(-) T cells, whereas T cells expressing autoreactive TCR were selected as CD4(+)CD25(+) T cells, which were exclusively dominant in recombination-activating gene 2-deficient Ld-nOVA x DO11.10 mice. In contrast, in DO11.10 mice, CD4(+)CD25(+) T cells expressed endogenous TCR alpha beta chains, which disappeared in recombination-activating gene 2-deficient DO11.10 mice. These results indicate that part of autoreactive T cells that have a high affinity TCR enough to cause clonal deletion could be positively selected as CD4(+)CD25(+) T cells in the thymus. Furthermore, it is suggested that endogenous TCR gene rearrangement might critically contribute to the generation of CD4(+)CD25(+) T cells from nonautoreactive T cell repertoire, at least under the limited conditions such as TCR-transgenic models, as well as the generation of CD4(+)CD25(-) T cells from autoreactive T cell repertoire.
방사선 선량관리시스템(Dose Track)을 이용한 일반촬영 환자피폭선량관리의 중요성 (2013)

목적: 방사선 선량관리시스템(Dose Track)을 통해 CT검사와 일반촬영검사의 유효선량을 비교하여 일반촬영 환자피폭선량관리의 중요성에 대하여 알아보고자 한다.
대상 및 방법: 2012년 11월 01일부터 2013년 2월 28일에 걸쳐 본원에 내원한 환자를 대상으로 방사선 선량관리시스템(Dose Track)을 이용하였다.
CT 환자누적선량의 체계적인...
Increased risk of developing Parkinson's disease for patients with major affective disorder: a register study (2001)

This study supports the hypothesis of a common aetiology for major affective disorder and Parkinson's disease.
Blends of POSS−PEO(<i>n</i>=4)<sub>8</sub> and High Molecular Weight Poly(ethylene oxide) as Solid Polymer Electrolytes for Lithium Batteries (2007)

Solid polymer electrolyte blends were prepared with POSS-PEO(n=4)8 (3K), poly(ethylene oxide) (PEO(600K)), and LiClO4 at different salt concentrations (O/Li = 8/1, 12/1, and 16/1). POSS-PEO(n=4)8/LiClO4 is amorphous at all O/Li investigated, whereas PEO(600K) is amorphous only for O/Li = 8/1 and semicrystalline for O/Li = 12/1 and 16/1. The tendency of PEO(600K) to crystallize limited the amount of POSS-PEO(n=4)(8) that could be incorporated into the blends, so that the greatest incorporation of POSS-PEO(n=4)(8) occurred for O/Li = 8/1. Blends of POSS-PEO(n=4)(8)/PEO(600K)/LiClO4 (O/Li = 8/1 and 12/1) microphase separated into two amorphous phases, a low T(g) phase of composition 85% POSS-PEO(n=4)(8)/15% PEO(600K) and a high T(g) phase of composition 29% POSS-PEO(n=4)(8)/71% PEO(600K). For O/Li = 16/1, the blends contained crystalline (pure PEO(600K)), and two amorphous phases, one rich in POSS-PEO(n=4)(8) and one rich in PEO(600K). Microphase, rather than macrophase separation was believed to occur as a result of Li(+)/ether oxygen cross-link sites. The conductivity of the blends depended on their composition. As expected, crystallinity decreased the conductivity of the blends. For the amorphous blends, when the low T(g) (80/20) phase was the continuous phase, the conductivity was intermediate between that of pure PEO(600K) and POSS-PEO(n=4)(8). When the high T(g) (70/30, 50/50, 30/70, and 20/80) phase was the continuous phase, the conductivity of the blend and PEO(600K) were identical, and lower than that for the POSS-PEO(n=4)(8) over the whole temperature range (10-90 degrees C). This suggests that the motions of the POSS-PEO(n=4)(8) were slowed down by the dynamics of the long chain PEO(600K) and that the minor, low Tg phase was not interconnected and thus did not contribute to enhanced conductivity. At temperatures above T(m) of PEO(600K), addition of the POSS-PEO(n=4)(8) did not result in conductivity improvement. The highest RT conductivity, 8 x 10(-6) S/cm, was obtained for a 60% POSS-PEO(n=4)(8)/40% PEO(600K)/LiClO4 (O/Li = 12/1) blend.
Single-snapshot DOA estimation and source number detection (1997)

We present a Bayesian solution to the problem of multiple direction of arrival (DOA) detection/estimation from a single temporal observation of array data, where the array can be of general configuration. The proposed method consists of multiple-step likelihood marginalizations using noninformative priors selected specifically to allow valid comparison of alternative model orders. This yields a novel DOA estimation cost function and a new detection algorithm useful for the single-snapshot case.
The membrane sealant poloxamer reduces membrane permeability in tibialis anterior muscles from dystrophic <i>mdx</i> mice (2007)

Duchenne muscular dystrophy is characterised by the loss of the membrane stabilizing protein dystrophin, resulting in an increased susceptibility to sarcolemmal injury. The membrane sealant Poloxamer 188 (P‐188) prevents sarcolemmal tearing in cardiac myocytes from dystrophic mdx mice. We tested the hypothesis that P‐188 would similarly reduce membrane tearing in skeletal muscles of mdx mice. Mdx and wild type mice were injected with Evans blue dye (EBD) an indicator of membrane permeability, then anesthetized for P‐188 (460mg/kg) or vehicle (200μL saline) infusion via the right jugular vein. The susceptibility of the tibialis anterior (TA) muscle to contraction‐induced injury (CI) was determined in situ and then prepared for histological quantification of EBD. TA muscles from mdx mice were more susceptible to CI than wild type mice, regardless of treatment. P‐188 decreased the proportion of EBD positive fibers by 53% in both uninjured and injured TA muscles from mdx mice (P<0.05). These findings indicate that while P‐188 does not alter the susceptibility to CI, it may play a role in maintaining sarcolemmal integrity in muscle fibers of mdx mice. Supported by the Muscular Dystrophy Association (USA).
Impact of component losses on the voltage boost properties and efficiency of the qZS-converter family (2011)

This paper is devoted to the quasi-Z-source (qZS) converter family. Recently, the qZS-converters have attracted high attention because of their specific properties of voltage boost and buck functions with a single switching stage, which could be especially advantageous in renewable energy applications. As main representatives of the qZS-converter family, the traditional quasi-Z-source inverter as well as two novel extended boost quasi-Z-source inverters are discussed. Steady state analysis of three main topologies operating in the continuous conduction mode is presented. Input voltage boost properties of converters are compared for an ideal case. Mathematical models of converters considering losses in components are derived. Practical boost properties of converters are compared to idealized ones and the impact of losses on the voltage boost properties of each topology is justified. Finally, the impact of losses in the components on the boost conversion efficiency is analyzed.
Structure-function analyses of the kit receptor for the steel factor (1996)

Binding of the Steel factor (SLF) to the product of the c-kit proto-oncogene stimulates the receptor's intrinsic tyrosine kinase that phosphorylates a set of cytoplasmic signaling molecules. Germ-line mutations in the genes that encode the receptor or the ligand result in remarkably similar phenotypes that affect melanogenesis, erythropoiesis and gametogenesis in mice. We concentrated on the initial events of the signal transduction pathway that underlies these processes. The extracellular portion of Kit is comprised of five immunoglobulin-(Ig)-like domains. Ligand binding to this domain induces rapid and extensive dimerization of the receptor molecules in a mechanism that involves monovalent binding of the dimeric ligand, followed by an increase in receptors' affinity and gradual stabilization of the dimers. It thus appears that Kit has at least two functions: ligand binding and ligand-induced receptor dimerization, in addition to the kinase activity. Both functions are independent of the transmembrane and cytoplasmic domains, as a recombinant soluble ectodomain retained high affinity to SLF and ligand-dependent dimerization. In order to correlate these functions with specific structures, we employed ligand-competitive monoclonal antibodies, soluble deletion mutants of the ectodomain and chimeric human-mouse Kit proteins. These approaches indicated that the N-terminal three Ig-like domains constitute the binding site, whose core is the second domain. Further experiments suggested that a putative dimerization site is distinct from the binding cleft and may be located on the fourth Ig-like domain.
Efficient Web-based access to multiple geographic databases through automatically generated wrappers (2002)

With the proliferation of various geographic database servers on the Internet, the need to access them simultaneously through the Web arises frequently for high-level decision making. The ongoing OpenGIS standard addresses many of the interoperability issues to make such global utilization of geographic databases possible. Based on the OpenGIS standard, the paper presents an object oriented architecture for the efficient Web based access to multiple geographic databases on the Internet. Called MEADOW, it provides a pair of automatically generated modules: the OpenGIS wrapper on the server side and the matching transparent access provider (TAP) on the client side. In cooperation with the wrapper, TAP supports an application's efficient access to the databases through prefetching and caching of remote objects.
A Comparative Analysis of Adaptive Digital Predistortion Algorithms for Multiple Antenna Transmitters (2015)

This paper presents a comparative study of adaptive algorithms for digital predistortion (DPD) in multiple antenna transmitters. Crossover predistorter (CO-DPD) and crosstalk canceling predistorter (CTC-DPD) were proposed to overcome the deleterious effect of RF crosstalk before the power amplifiers (PA) on digital predistortion (DPD) in multiple antenna transmitters. This paper discusses the linearization performance and computational complexity of least mean square (LMS) and recursive least squares (RLS) adaptive algorithms for CO-DPD and CTC-DPD. The adaptive predistortion algorithms for a single antenna transmitter can be extended for CO-DPD, by incorporating the DPD coefficients of more than one branch in to one filter coefficient vector of the adaptive algorithm. The adaptive CTC-DPD involves predistorters for each transmitter running in parallel with the adaptive algorithms that track the coupling between the transmitters. The computational complexity of CTC-DPD is considerably lower compared to CO-DPD, as it has lesser predistorter branches. It is estimated that the number of computations needed per sample duration, for the real-time operation of the adaptive CTC-DPD is 47% lesser compared to CO-DPD for a two-antenna transmitter, when a 9th order memory polynomial with 3 memory taps was used. The linearization performances of these adaptive predistortion techniques for two and four antenna transmitters are evaluated through simulations using QPSK, 16-QAM, UMTS, and LTE signals. It is observed that CTC-DPD performs approximately identical to CO-DPD in all the examined cases. In the presence of frequency selective crosstalk, an extension of CTC-DPD which can pre-cancel such crosstalk, performs considerably better than CO-DPD, which cannot model the frequency selectivity of the crosstalk.
Receptor Tyrosine Phosphatase β (RPTPβ) Activity and Signaling Are Attenuated by Glycosylation and Subsequent Cell Surface Galectin-1 Binding (2008)

O-Mannosyl-linked glycosylation is abundant within the central nervous system, yet very few glycoproteins with this glycan modification have been identified. Congenital diseases with significant neurological defects arise from inactivating mutations found within the glycosyltransferases that act early in the O-mannosyl glycosylation pathway. The N-acetylglucosaminyltransferase known as GnT-Vb or -IX is highly expressed in brain and branches O-mannosyl-linked glycans. Our results using SH-SY5Y neuroblastoma cells indicate that GnT-Vb activity promotes the addition of the O-mannosyl-linked HNK-1 modification found on the developmentally regulated and neuron-specific receptor protein-tyrosine phosphatase beta (RPTPbeta). These changes in glycosylation accompany decreased cell-cell adhesion and increased rates of migration on laminin. In addition, we show that expression of GnT-Vb promotes its dimerization and inhibits RPTPbeta intrinsic phosphatase activity, resulting in higher levels of phosphorylated beta-catenin, suggesting a mechanism by which GnT-Vb glycosylation couples to changes in cell adhesion. GnT-Vb-mediated glycosylation of RPTPbeta promotes galectin-1 binding and RPTPbeta levels of retention on the cell surface. N-Acetyllactosamine, but not sucrose, treatment of cells results in decreased RPTP retention, showing that galectin-1 binding contributes to the increased retention after GnT-Vb expression. These results place GnT-Vb as a regulator of RPTPbeta signaling that influences cell-cell and cell-matrix interactions in the developing nervous system.
Mechanism of electrode erosion in pulsed discharges in water with a pulse energy of ∼ 1 J (1997)

It has been shown that electrode erosion in pulsed discharges in water is governed by a thermal cavitation effect. Blowing gas through the water modifies the cavitation effect, simplifies breakdown, and allows solid electrodes to be used.
The influence of graded doses of vitamin A upon pathological changes in the central nervous system of the rat, with suggestions for a prophylactic assay of the vitamin (1940)

Research Article| February 01 1940 The influence of graded doses of vitamin A upon pathological changes in the central nervous system of the rat, with suggestions for a prophylactic assay of the vitamin J. T. Irving; J. T. Irving 1The Rowett Research Institute, Aberdeen Search for other works by this author on: This Site PubMed Google Scholar M. B. Richards M. B. Richards 1The Rowett Research Institute, Aberdeen Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1940) 34 (2): 198–201. https://doi.org/10.1042/bj0340198 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation J. T. Irving, M. B. Richards; The influence of graded doses of vitamin A upon pathological changes in the central nervous system of the rat, with suggestions for a prophylactic assay of the vitamin. Biochem J 1 February 1940; 34 (2): 198–201. doi: https://doi.org/10.1042/bj0340198 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1940 CAMBRIDGE UNIVERSITY PRESS1940 Article PDF first page preview Close Modal You do not currently have access to this content.
Identification of two proteins (actin-binding protein and P235) that are hydrolyzed by endogenous Ca2+-dependent protease during platelet aggregation. (1985)

Our previous research has shown that the Ca2+-dependent protease within platelets is activated when platelets aggregate, resulting in the production of three polypeptides (Mr = 200,000, 100,000, and 91,000). We have now shown that these three polypeptides arise from the hydrolysis of actin-binding protein. An antibody against actin-binding protein raised in rabbits was shown to be specific for actin-binding protein on immunoblots of total platelet proteins. This antibody reacted with additional polypeptides of Mr = 200,000, 100,000, and 91,000 on immunoblots of the proteins of thrombin-activated platelets. Actin-binding protein was purified from fresh, human platelet concentrate and hydrolyzed with platelet-derived Ca2+-dependent protease; hydrolysis resulted in the appearance of three polypeptides with molecular weights and isoelectric points identical to those of the three polypeptides generated within intact, aggregating platelets. Production of these polypeptides was inhibited by leupeptin and by the chelation of Ca2+. Hydrolysis of actin-binding protein was observed at micromolar Ca2+ concentrations, demonstrating that the level of Ca2+ in aggregated platelets is sufficient to account for the hydrolysis of actin-binding protein by the Ca2+-dependent protease. P235 was also purified and tested for its susceptibility to the protease. It was hydrolyzed by the Ca2+-dependent protease, and two polypeptides (Mr = 200,000 and 46,000) were produced. Antibodies against P235 raised in rabbits reacted only with P235 on immunoblots of total platelet proteins. These antibodies also reacted with polypeptides of Mr = 200,000 and 46,000 on immunoblots of thrombin-activated platelets. These data show that both actin-binding protein and P235 are cleaved during thrombin-induced platelet aggregation and suggest that the activation of the Ca2+-dependent protease may permit reorganization of the platelet cytoskeleton in aggregating platelets.
Named graphs, provenance and trust (2005)

The Semantic Web consists of many RDF graphs nameable by URIs. This paper extends the syntax and semantics of RDF to cover such Named Graphs. This enables RDF statements that describe graphs, which is beneficial in many Semantic Web application areas. As a case study, we explore the application area of Semantic Web publishing: Named Graphs allow publishers to communicate assertional intent, and to sign their graphs; information consumers can evaluate specific graphs using task-specific trust policies, and act on information from those Named Graphs that they accept. Graphs are trusted depending on: their content; information about the graph; and the task the user is performing. The extension of RDF to Named Graphs provides a formally defined framework to be a foundation for the Semantic Web trust layer.