gebhart/patrepeval huggingface dataset:
Chiral biphenyl bis(crown ethers): synthesis and resolution (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChiral biphenyl bis(crown ethers): synthesis and resolutionGoeran Lindsten, Olof Wennerstroem, and Roland IsakssonCite this: J. Org. Chem. 1987, 52, 4, 547–554Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/jo00380a013https://doi.org/10.1021/jo00380a013research-articleACS PublicationsRequest reuse permissionsArticle Views1570Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
EL AREA FARMACEUTICA, EN LA DISYUNTIVA PARA PLANEAR EL FUTURO DE SUS PROFESIONALES (1995)

DEL 18 AL 27 DE SEPTIEMBRE SE LLEVO A CABO EN LA FACULTAD DE QUIMICA (FQ) EL TERCER CURSO INTERNACIONAL DE BIOQUIMICA CLINICA AVANZADA, CON EL PROPOSITO DE ACTUALIZAR AL PERSONAL QUE LABORA EN EL AREA DE LA BIOQUIMICA CLINICA Y FAVORECER EL INTERCAMBIO DE IDEAS Y CONOCIMIENTOS ENTRE LOS PROFESIONALES DE ESTE CAMPO DE ESTUDIO. EN EL CURSO PARTICIPARON ESPECIALISTAS DEL CONSEJO BRITANICO Y DEL INSTITUTO NACIONAL DE CARDIOLOGIA, ENTRE OTRAS INSTITUCIONES.
The Role of the Management Sciences in Research on Personalization (2003)

We present a review of research studies that deal with personalization and synthesize current knowledge about these areas. We identify issues that we envision will be of interest to researchers working in the management sciences, taking an interdisciplinary approach that spans the areas of economics, marketing, information technology (IT), and operations research. We present a framework for personalization that allows us to identify key players in the personalization process as well as key stages of personalization. The framework enables us to examine the strategic role of personalization in the interactions between a firm and other key players in the firm's value system. We conceptualize the personalization process as consisting of three stages: (1) learning about consumer preferences, (2) matching offerings to customers, and (3) evaluation of the learning and matching processes. This review focuses on the learning stage, with an emphasis on utility-based approaches to estimate preference functions using data on customer interactions with a firm.
<i>MFN2</i> mutations cause severe phenotypes in most patients with CMT2A (2011)

We find MFN2 mutations particularly likely to cause severe neuropathy that may be primarily motor or motor accompanied by prominent proprioception loss. Disruption of functional domains of the protein was particularly likely to cause neuropathy.
Probing the substrate specificities of matriptase, matriptase‐2, hepsin and DESC1 with internally quenched fluorescent peptides (2009)

Type II transmembrane serine proteases are an emerging class of proteolytic enzymes involved in tissue homeostasis and a number of human disorders such as cancer. To better define the biochemical functions of a subset of these proteases, we compared the enzymatic properties of matriptase, matriptase-2, hepsin and DESC1 using a series of internally quenched fluorogenic peptide substrates containing o-aminobenzoyl and 3-nitro-tyrosine. We based the sequence of the peptides on the P4 to P4' activation sequence of matriptase (RQAR-VVGG). Positions P4, P3, P2 and P1' were substituted with nonpolar (Ala, Leu), aromatic (Tyr), acid (Glu) and basic (Arg) amino acids, whereas P1 was fixed to Arg. Of the four type II transmembrane serine proteases studied, matriptase-2 was the most promiscuous, and matriptase was the most discriminating, with a distinct specificity for Arg residues at P4, P3 and P2. DESC1 had a preference similar to that of matriptase, but with a propensity for small nonpolar amino acids (Ala) at P1'. Hepsin shared similarities with matriptase and DESC1, but was markedly more permissive at P2. Matriptase-2 manifested broader specificities, as well as substrate inhibition, for selective internally quenched fluorescent substrates. Lastly, we found that antithrombin III has robust inhibitory properties toward matriptase, matriptase-2, hepsin and DESC1, whereas plasminogen activator inhibitor-1 and alpha(2)-antiplasmin inhibited matriptase-2, hepsin and DESC1, and to a much lesser extent, matriptase. In summary, our studies revealed that these enzymes have distinct substrate preferences.
The ‘Transition from School to Work’ in 1980/81: a dynamic account (1983)

Abstract This paper describes the experiences of a sample of Scottish school leavers during their first year in the labour market in 1980 and 1981. The paper describes the absorption of summer term leavers into the labour market and their movements between employment, unemployment and the Youth Opportunities Programme (YOP). The summer months continued to be the main recruitment season for school leavers; after October few school leavers found employment without first going on YOP. Yet a majority of entrants to YOP did not find work at the end of their schemes, and YOP had become a major ingredient of a new pattern of instability in the youth labour market. School leavers' chances of employment varied with their school qualifications and with the area they lived in. The paper concludes with a discussion of the Youth Training Scheme, which comes into operation in September 1983.
Fumigant activity of plant essential oils and components from horseradish (<i>Armoracia rusticana</i>), anise (<i>Pimpinella anisum</i>) and garlic (<i>Allium sativum</i>) oils against <i>Lycoriella ingenua</i> (Diptera: Sciaridae) (2006)

Plant essential oils from 40 plant species were tested for their insecticidal activities against larvae of Lycoriella ingénue (Dufour) using a fumigation bioassay. Good insecticidal activity against larvae of L. ingenua was achieved with essential oils of Chenopodium ambrosioides L., Eucalyptus globulus Labill, Eucalyptus smithii RT Baker, horseradish, anise and garlic at 10 and 5 microL L(-1) air. Horseradish, anise and garlic oils showed the most potent insecticidal activities among the plant essential oils. At 1.25 microL L(-1), horseradish, anise and garlic oils caused 100, 93.3 and 13.3% mortality, but at 0.625 microL L(-1) air this decreased to 3.3, 0 and 0% respectively. Analysis by gas chromatography-mass spectrometry led to the identification of one major compound from horseradish, and three each from anise and garlic oils. These seven compounds and m-anisaldehyde and o-anisaldehyde, two positional isomers of p-anisaldehyde, were tested individually for their insecticidal activities against larvae of L. ingenua. Allyl isothiocyanate was the most toxic, followed by trans-anethole, diallyl disulfide and p-anisaldehyde with LC(50) values of 0.15, 0.20, 0.87 and 1.47 microL L(-1) respectively.
An Adaptive Transport Framework for Web Services (2008)

In this paper, we present an adaptive transport framework which addresses multiple message exchange patterns (MEPs) and transparent switching between multiple transports for Web services. In the framework, we separate the transportation process into transport input stage and transport output stage by using pipelined pattern. Moreover, we introduce a set of abstractions, such as transport protocol, transport session, transport handler and transport object, to provide a uniform programming model for both Web services components and the transport framework. In addition, we introduce an algorithm in transport output stage in order to handle messages of out-* MEPs and switching between multiple transports. Besides, we implement HTTP and JMS protocols based on this framework for demonstrations and evaluate its performance by comparing it with Tomcat 6.0. The results show that our framework supports multiple MEPs and transparent switching between multiple transports, as well as guarantees the performance of the transport implementation, so the framework can serve as a fundamental transport layer for Web services.
New diarylmethanofullerene derivatives and their properties for organic thin-film solar cells (2009)

A number of diarylmethanofullerene derivatives were synthesized. The cyclopropane ring of the derivatives has two aryl groups substituted with electron-withdrawing and -donating groups, the latter with long alkyl chains to improve solubility in organic solvents, an important property in processing cells. First reduction potentials of most derivatives were less negative than that of [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), which is possibly ascribed to their electron-withdrawing nature. Organic thin-film photovoltaic cells fabricated with poly(3-hexylthiophene) (P3HT) as the electron-donor and diarylmethanofullerene derivatives as the electron-acceptor material were examined. The {(methoxycarbonyl)phenyl[bis(octyloxy)phenyl]methano}fullerene showed power conversion efficiency as high as PCBM, but had higher solubility in a variety of organic solvents than PCBM. The V(oc) value was higher than that of PCBM, which is derived from the electron-donating (octyloxy)phenyl group, possibly raising the LUMO level. Photovoltaic effects of the devices fabricated with the derivatives having some electron-withdrawing groups were also examined.
Investigation of flux leakages and EMC problems in wireless charging systems for EV and other mobile applications (2012)

High Frequency Wireless Planar Transformers (HFWPT) are an up-and-coming technology which can be used for designing an electric vehicle (EV) on board wireless battery charging platform. In this paper, HFWPTs are used to investigate the flux leakages and other EMC problems which are associated with wireless charging system's efficiency. The HFWPT was designed using the bifilar winding concept on PCB. A LLC resonant converter has been designed to improve the conversion efficiency with a maximized air gap. Assisted by a near-field scanner, the magnetic field has been analyzed with and without a magnetic ferrite core at resonant frequency. The magnetic ferrite core in this arrangement is used to minimize flux leakages and to increase the magnetizing impedance.
Purification and Functionalization of Carbon Nanotubes by Classical and Advanced Oxidation Processes (2009)

Advanced oxidation technologies (AOT) were applied for the production of accurately controlled oxidized multi-walled carbon nanotubes. Fenton process is effective to get carboxylic (-COO- or -COOH) and OH groups on the surface of carbon nanotubes while Photofenton and UV/H2O2 processes mostly produce OH groups on surface of multiwalled carbon nanotubes (MWCNT). All of them preserve the structure of MWCNT allowing to achieve accurately controlled oxidized MWCNT. Fourier transform infrared spectroscopy (FTIR) and thermogravimetical analysis (TGA) show that the acid treatment is the more efficient technique to generate COOH groups on MWCNT surface. However, this chemical technique generates strong damages on the MWCNT structure, as demonstrated by TGA, field emission scanning electron microscopy and transmission electron microscopy results.
The conformation of polyriboadenylic acid at low temperature and neutral pH. A single‐stranded rodlike structure (1975)

Abstract The conformation of single‐stranded polyrA in aqueous solution has been measured at temperatures down to −12°C. The radius of gyration of low‐molecular‐weight polyrA varies very little with temperature in this range. By studying the dependence of radius of gyration on temperature for several polyrA fractions, we show that the dependence of the radius upon chain length is consistent with formation of a single‐stranded rodlike structure at low temperature. The structure has an approximate length of 3.2 Å/nucleotide.
Preparation of Monofunctional Undecamethylcyclohexasilanes (1971)

Abstract A preparative route to undecamethylcyclohexasilane and its chloro and fluoro derivatives is described
A scheme for lensless X-ray microscopy combining coherent diffraction imaging and differential corner holography (2012)

We successfully use the corners of a common silicon nitride supporting window in lensless X-ray microscopy as extended references in differential holography to obtain a real space hologram of the illuminated object. Moreover, we combine this method with the iterative phasing techniques of coherent diffraction imaging to enhance the spatial resolution on the reconstructed object, and overcome the problem of missing areas in the collected data due to the presence of a beam stop, achieving a resolution close to 85 nm.
Using microbial reduction to synthesize carbacyclin. (1986)

Microbial reduction of 7-methoxycarbonyl bicyclo[4. 3. 0]non-3-en-8-one ((±)-3) afforded the optically active (-)-3, which was efficiently converted by ring contraction using thallium (III) nitrate to the intermediate (11) used to synthesize carbacyclin (1).
Mitochondrial DNA damage in non-melanoma skin cancer (2003)

Mitochondrial DNA (mtDNA) damage, predominantly encompassing point mutations, has been reported in a variety of cancers. Here we present in human skin, the first detailed study of the distribution of multiple forms of mtDNA damage in nonmelanoma skin cancer (NMSC) compared to histologically normal perilesional dermis and epidermis. We present the first entire spectrum of deletions found between different types of skin tumours and perilesional skin. In addition, we provide the first quantitative data for the incidence of the common deletion as well as the first report of specific tandem duplications in tumours from any tissue. Importantly, this work shows that there are clear differences in the distribution of deletions between the tumour and the histologically normal perilesional skin. Furthermore, DNA sequencing of four mutation 'hotspot' regions of the mitochondrial genome identified a previously unreported somatic heteroplasmic mutation in an SCC patient. In addition, 81 unreported and reported homoplasmic single base changes were identified in the other NMSC patients. Unlike the distribution of deletions and the heteroplasmic mutation, these homoplasmic mutations were present in both tumour and perilesional skin, which suggests that for some genetic studies the traditional use of histologically normal perilesional skin from NMSC patients may be limited. Currently, it is unclear whether mtDNA damage has a direct link to skin cancer or it may simply reflect an underlying nuclear DNA instability.
Origin-destination matrix estimation for pedestrian networks with Bi-directional flow effects (2006)

11th International Conference of Hong Kong Society for Transportation Studies: Sustainable Transportation, Kowloon, 9-11 December 2006
RE: STANDARDIZED ULTRASOUND METHOD FOR ASSESSING DETRUSOR MUSCLE THICKNESS IN CHILDREN (2001)

No AccessJournal of UrologyCLINICAL UROLOGY: Letters to the Editor1 Aug 2001RE: STANDARDIZED ULTRASOUND METHOD FOR ASSESSING DETRUSOR MUSCLE THICKNESS IN CHILDREN McClellan M. Walther, V.S. Kirchin, T. Cuming, R.C. Beard, and P.J. Thomas McClellan M. WaltherMcClellan M. Walther More articles by this author , V.S. KirchinV.S. Kirchin More articles by this author , T. CumingT. Cuming More articles by this author , R.C. BeardR.C. Beard More articles by this author , and P.J. ThomasP.J. Thomas More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)66028-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "RE: STANDARDIZED ULTRASOUND METHOD FOR ASSESSING DETRUSOR MUSCLE THICKNESS IN CHILDREN." The Journal of Urology, 166(2), pp. 633–634 References 1 : Ultrasound estimated bladder wall volume: variability and relation to intravesical volume. Neurourol Urodyn1999; 18: 397. Google Scholar 2 : Ultrasonic estimation of bladder weight as a measure of bladder hypertrophy in men with infravesical obstruction: a preliminary report. Urology1996; 47: 942. Google Scholar Department of Urology, Worthing Hospital, Worthing, United Kingdom, Department of Urology, Royal Sussex County Hospital, Brighton, United Kingdom© 2001 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 166Issue 2August 2001Page: 633-634 Advertisement Copyright & Permissions© 2001 by American Urological Association, Inc.MetricsAuthor Information McClellan M. Walther More articles by this author V.S. Kirchin More articles by this author T. Cuming More articles by this author R.C. Beard More articles by this author P.J. Thomas More articles by this author Expand All Advertisement PDF downloadLoading ...
Cross-Linking of Soluble Extensin in Isolated Cell Walls (1984)

The extensin component of primary cell walls has generally been considered to be an intrinsically insoluble cell wall glycoprotein. Recent data have established that cell wall extensin is in fact secreted in a soluble monomeric form which slowly becomes insolubilized in the cell wall probably through the oxidative formation of isodityrosine cross-links. We now show that isolated cell walls from aerated root slices of Daucus carota have the capacity to insolubilize extensin through the formation of isodityrosine. This in vitro cross-linking is specific for the extensin glycoprotein, as other wall proteins are not cross-linked by the isolated wall system. Although extensin can be cross-linked in solution by peroxidase and H(2)O(2), dityrosine and not isodityrosine is the phenolic cross-link formed. Wall-catalyzed cross-linking of soluble extensin is inhibited by l-ascorbate, and both the initial rate and total extent of cross-linking are inhibited by acidic pH in the physiological range (pH 4 to 6). We suggest several mechanisms by which acid might inhibit cross-linking and propose that cytoplasmic factors (ascorbate and/or hydrogen ions) may regulate the solubility of extensin in vivo.
The isolation of homogeneous leader peptidase from a strain of Escherichia coli which overproduces the enzyme. (1982)

Leader (signal) peptidases cleave the NH2-terminal leader sequences of newly synthesized secreted and membrane proteins during, or shortly after, they insert across the membrane. We have constructed a plasmid, pPS9, in which the structural gene for Escherichia coli leader peptidase is under transcriptional control of a lambda promoter, PR. pPS9 also codes for a temperature-sensitive lambda repressor, causing repression of expression of the plasmid leader peptidase gene at 30 degrees C and rapid synthesis of this enzyme at 42 degrees C. Under appropriate growth regimens, leader peptidase is overproduced 75-fold. Leader peptidase from this strain has been purified to homogeneity. It consists of a 37,000-dalton polypeptide which co-migrates with enzyme activity on DEAE-cellulose and chromatofocusing chromatography. Antibody to this leader peptidase is described.
Observation of Strong Ordering in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ga</mml:mi></mml:mrow><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">In</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>−</mml:mo><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mi mathvariant="normal">P</mml:mi></mml:math>alloy semiconductors (1988)

Extremely strong superstructure reflections have been observed for the first time by transmission electron microscopy for (110) edge-on ${\mathrm{Ga}}_{0.5}$${\mathrm{In}}_{0.5}$P crystals lattice matched to GaAs. Growth was carried out by metal-organic vapor-phase epitaxy. A monolayer superlattice (SL) of (Ga-rich plane) (In-rich plane)... is formed along [\ifmmode\bar\else\textasciimacron\fi{}111] and [1\ifmmode\bar\else\textasciimacron\fi{}11] directions. The substrates are found to be playing a vital role in the SL formation. Band-gap energy reduction (\ensuremath{\cong}80 meV) has been observed for layers with these SL's.
The Divine Proportion (1970)

Using simple mathematical formulas, most as basic as Pythagoras's theorem and requiring only a very limited knowledge of mathematics, Professor Huntley explores the fascinating relationship between geometry and aesthetics. Poetry, patterns like Pascal's triangle, philosophy, psychology, music, and dozens of simple mathematical figures are enlisted to show that the "divine proportion" or "golden ratio" is a feature of geometry and analysis which awakes answering echoes in the human psyche. When we judge a work of art aesthetically satisfying, according to his formulation, we are making it c
Connection between x waves, fourier-bessel series and optimal modelling aperture for circular symmetric arrays (2006)

This study concerns two issues. Firstly an equiva- lence is given between the use of 1D Fourier-Bessel series and the X Wave Transform, as applied to annular arrays and the computation and tuning of linear fields. Secondly, an optimal choice of modelling aperture in the Fourier-Bessel analysis is suggested. The Fourier-Bessel approach is a numerical method which has been developed and implemented for calculation and tuning of linear lossless fields in both continuous wave and pulsed wave cases. The X Wave Transform is a theoretical mathematical method for expressing an arbitrary linear lossless fields as a summation of weighted X Wave expansions. Our discussion establishes a connection between these two studies, showing that the numerical Fourier-Bessel approach is in the limit equivalent to the analytical X wave approach to the description of circular symmetric fields. Furthermore it suggests a numerical optimisation of the Fourier-Bessel approach by implementing of a one-off optimal modelling aperture which replaces the previous iterative approach. Potential applications exist in the area of optimal ultrasound field calculation and tuning, for example in the study of contrast agent responses.
Fiber Optic Radiation Dosimetry (1990)

A great deal of effort has been expended in recent years in developing fiber optic instruments, such as temperature, pressure, mechanical, and chemical sensors. However, very little has been done in the area of ionizing radiation detection using fiber optic based instruments. This is in spite of the inability of conventional radiation detectors to perform dose measurements remote from high field environs or in small volumes, such as in situ or in vivo dosimetery. A microminiature radiation detector coupled to an optical fiber could clearly overcome these conventional detector limitations. The present paper describes such a radiation dosimeter using a storage phosphor coupled to an optical fiber suitable for ionizing radiation dosimetry.