gebhart/patrepeval huggingface dataset:
A Data Management Method for Remote and Long-Term Seafloor Observation System (2019)

The deep seafloor is closest to the Earth’s interior and there are complicated interactions in the physical and biological processes of the seafloor. Oceanographic parameters such as temperature, salinity, and ocean current can provide support for climate prediction. Therefore, the long-term observation of the deep seafloor is critical to the study of global climate change and the biodiversity in complex environments. For the requirements of long-term observation and remote data transmission in the deep sea of the South China Sea, a seafloor observation prototype system is designed in this paper as a stand-alone observation platform. We then proposed a date management method based on Controller Area Network to ensure the data quality. Distributed data management can be performed through system layering, and strict data transmission standards are established between each layer. At the same time, aiming at the difficulty of seafloor video data transmission in real-time, a new solution based on satellite communication technology, object detection technology, and high-efficiency compression coding technology of video images is proposed to provide support for seafloor biodiversity research. The observation data from the experiment are given, and these results show that the system can meet the requirements of long-term observation and remote real-time data transmission, and the reliability of the system is verified.
Lung structure and function in cigarette smokers. (1994)

The reduction in FEV1 associated with chronic cigarette smoking can be partially explained by loss of lung elastic recoil pressure which reduces the force driving air out of the lung. This loss of elastic recoil pressure is attributed to microscopic enlargement of the air spaces rather than to grossly visible emphysema. The exact nature of the lesions responsible for the peripheral airways obstruction remains to be identified.
Intubation Bougie Dissection of Tracheal Mucosa and Intratracheal Airway Obstruction (2008)

Intubation bougies are commonly used to aid in intubation when an optimal view of the larynx is not obtained. We describe a case of tracheal perforation using a disposable intubation bougie resulting in a complete intratracheal airway obstruction relieved by cricothyrotomy. Disposable intubation bougies may have mechanical properties that differ from their nondisposable counterparts making complications more likely.
Strength, Volume Changes, and Sulfate Resistance of Mortars Containing Portland-Pozzolan Cements (1950)

This paper may be considered as a supplement to an earlier paper dealing with the properties of mortars and concretes containing portland-pozzolan cements and other blends. Herein, for mortars there are given the strengths and volume changes up to the age of 10 yr. and the resistance to the action of sodium-sulfate solutions up to the age of one year. Mortar specimens containing portland cements within the ordinary range of composition, under laboratory conditions of continuous wet storage, exhibited retrogression in both tensile and compressive strengths. Corresponding specimens containing cement replacements of finely divided pozzolanic materials in general showed no such retrogression. Those containing the less active volcanic glasses, such as pumicite, continued to increase in tensile strength up to the age of 10 yr.; those containing the more active opaline shales generally acquired their maximum strength at an earlier age, but some continued to increase in compressive strength up to the age of 10 yr. Under continuous drying conditions, after a preliminary period of moist curing, mortars containing portland cements within the ordinary range of composition continued to increase in strength up to the age of 10 yr. This was also true for blended cements where the replacement was 30 per cent or less, including not only such pozzolanic materials as volcanic glasses, opaline shales, and calcined clays, but also including limestone dust. In general, the long-time drying shrinkage of mortars containing blended cements was greater than that of mortar containing the corresponding straight portland cement; blended cements containing limestone replacements were exceptions. The long-time drying shrinkage of mortars containing cements high in tricalcium silicate was less than that for corresponding mortars containing cements low in tricalcium silicate. The long-time expansion of mortars under continuously wet conditions was somewhat greater for portland-pozzolan cements than for the corresponding straight portland cement. The use of such pozzolans as Monterey shale and pumicite in blended cements materially improved resistance to sulfate action. In general, blends containing calcined or uncalcined clays, and crystalline silicas such as quartz and granite were little, if any, more resistant to sulfate action than the corresponding straight portland cement. The use of limestone dust led to some improvement in sulfate resistance.
Epidemiological characteristics of chronic fatigue-&nbsp;syndrome/myalgic encephalomyelitis in Australian patients (2016)

This is the first study to summarize sociodemographic and illness characteristics of a cohort of Australian CFS/ME patients. This is vital for identifying potential risk factors and predictors associated with CFS/ME and for guiding decisions regarding health care provision, diagnosis, and management.
Model Based Object Recognition Using Modified Coded Boundary Representation (MCBR) Method. (1992)

This study aims at building the object recognition system which uses the Coded Boundary Representation (CBR) method to store shape data in computers. The CBR method was originally developed M a simple 2-D CAD model, and it can represent a shape as 8 sim-ple form d Ests and operate the shape qualitatively in a nonnumtrical way(&apos;). However, it can&apos;t represenk a shape in detail because of these features, it is difficult to use the methd in the object recognition system without modification. Therefore this paper describes the modification of the CBR method (which is called the MCBR method), the structure of shape models stored in cornpoten, and shows the system scheme and features. The system consists primarily of two parts, which are cdled the h-age Processing Part gnd the Shape Understanding Part. The role of the former is to extract segments from the original data using Hough transformation. The role of the latter is to reconstruct the shape wing the segments in the MCBR method. Then we demonstrate the effectir~ncss of the MCBR method for object recognition with some illustrative exmples.
Dolosigranulum pigrum Modulates Immunity against SARS-CoV-2 in Respiratory Epithelial Cells (2021)

In a previous work, we demonstrated that nasally administered <i>Dolosigranulum pigrum</i> 040417 beneficially modulated the respiratory innate immune response triggered by the activation of Toll-like receptor 3 (TLR3) and improved protection against Respiratory Syncytial Virus (RSV) in mice. In this work, we aimed to evaluate the immunomodulatory effects of <i>D. pigrum</i> 040417 in human respiratory epithelial cells and the potential ability of this immunobiotic bacterium to increase the protection against Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The respiratory commensal bacterium <i>D. pigrum</i> 040417 differentially modulated the production of IFN-β, IL-6, CXCL8, CCL5 and CXCL10 in the culture supernatants of Calu-3 cells stimulated with poly(I:C) or challenged with SARS-CoV-2. The differential cytokine profile induced by the 040417 strain was associated with a significant reduction in viral replication and cellular damage after coronavirus infection. Of note, <i>D. pigrum</i> 030918 was not able to modify the resistance of Calu-3 cells to SARS-CoV-2 infection, indicating a strain-specific immunomodulatory effect for respiratory commensal bacteria. The findings of this work improve our understanding of the immunological mechanisms involved in the modulation of respiratory immunity induced by respiratory commensal bacteria, by demonstrating their specific effect on respiratory epithelial cells. In addition, the results suggest that particular strains such as <i>D. pigrum</i> 040417 could be used as a promising alternative for combating SARS-CoV-2 and reducing the severity of COVID-19.
Fault Detection and Isolation on the Basis of Dynamic Process Models (1990)

This paper outlines the basic concept of fault detection and isolation (FDI) in dynamic systems based on analytical process models and briefly reviews the most important approaches. Emphasis is placed upon residual generation using state observation techniques. Because of the strong impact of parameter variations on the applicability and efficiency of model-based FDI, the issues of parameter sensitivity as well as the design of robust FDI schemes are addressed in more detail.
Observation of Fano resonance using a coupled resonator metamaterial composed of meta-atoms arranged by double periodicity (2015)

Abstract We studied the transmission characteristics of a planar metamaterial consisting of an array of electric split-ring resonators (eSRRs) with double periodicity. Because of coupling between different resonant modes induced by different lattice periods in metamaterials with double periodicity, the appearance of Fano resonance can be expected in the same manner as that in the case of coupled classical oscillators. We fabricated complementary eSRRs and verified that a Fano-like spectral shape appeared in the transmission spectra of eSRRs with double periodicity in the terahertz region.
Rate Control for Hierarchical B-picture Coding with Scaling-factors (2007)

The coding performance can be further improved when the hierarchical B-picture coding is introduced into H.264/AVC. However, the existing rate control schemes can not work efficiently in such new coding framework. This paper proposes a novel rate control algorithm when hierarchical B-picture coding is used in H.264/AVC. Firstly, a set of scaling-factors applied in designing cascaded quantizer for the B frames at different temporal levels is introduced. Based on the designed scaling-factors, an efficient bit-allocation strategy for hierarchical B-picture coding is presented. The experiments show that the proposed rate control algorithm can further improve PSNR up to 0.7dB compared to the existing hierarchical B-picture coding in H.264/AVC, while the mismatch of target bit rate and real bit rate does not exceed 2%.
APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress (2016)

The Xenopus laevis APE2 (apurinic/apyrimidinic endonuclease 2) nuclease participates in 3'-5' nucleolytic resection of oxidative DNA damage and activation of the ATR-Chk1 DNA damage response (DDR) pathway via ill-defined mechanisms. Here we report that APE2 resection activity is regulated by DNA interactions in its Zf-GRF domain, a region sharing high homology with DDR proteins Topoisomerase 3α (TOP3α) and NEIL3 (Nei-like DNA glycosylase 3), as well as transcription and RNA regulatory proteins, such as TTF2 (transcription termination factor 2), TFIIS, and RPB9. Biochemical and NMR results establish the nucleic acid-binding activity of the Zf-GRF domain. Moreover, an APE2 Zf-GRF X-ray structure and small-angle X-ray scattering analyses show that the Zf-GRF fold is typified by a crescent-shaped ssDNA binding claw that is flexibly appended to an APE2 endonuclease/exonuclease/phosphatase (EEP) catalytic core. Structure-guided Zf-GRF mutations impact APE2 DNA binding and 3'-5' exonuclease processing, and also prevent efficient APE2-dependent RPA recruitment to damaged chromatin and activation of the ATR-Chk1 DDR pathway in response to oxidative stress in Xenopus egg extracts. Collectively, our data unveil the APE2 Zf-GRF domain as a nucleic acid interaction module in the regulation of a key single-strand break resection function of APE2, and also reveal topologic similarity of the Zf-GRF to the zinc ribbon domains of TFIIS and RPB9.
cAMP and adenylate cyclase activity in Streptomyces granaticolor (1984)

Intracellular and extracellular cyclic adenosine 3′,5′-monophosphate (cAMP) levels were determined during the growth of Streptomyces granaticolor. The intracellular level of cAMP represents not more than 10% of the total amount. cAMP synthesis varies in cultures growing on different carbon sources. The activity of adenylate cyclase in intact cells is strictly dependent on the presence of a metabolizable carbon source.
Characteristics, clinical outcome, and prognostic significance of <scp>IDH</scp> mutations in <scp>AML</scp> (2015)

The pathophysiology of IDH mutations in tumorigenesis is increasingly described, yet the prognostic significance of IDH1 and IDH2 mutations in AML remains controversial. The primary objective of this study was to define the natural history and prognosis of patients with AML and IDH1 or IDH2 mutations and provide historical survival expectations. A total of 826 patients treated from 2010 to 2014 at a single institution were evaluated, including 167 patients (20%) with AML and IDH1 or IDH2 mutations. Median age was 62 years (range 18-92). There were 59 IDH1-R132, 83 IDH2-R140, and 23 IDH2-R172 mutations. Clinicopathologic characteristics associated with IDH-mutations included older age, less frequent therapy-related status, and increased incidence of intermediate-risk cytogenetics, FLT3-ITD mutations, and NPM1 mutations. Remission rates (CR/CRi) by AML treatment status were: induction, 68%; Salvage-1 (S1), 42%; and Salvage-2 and beyond (S2+), 27%. No difference in response was identified by IDH mutation status. Similarly, overall survival (OS) was not dependent on IDH status within any cohort. The median OS was 15.4 months in induction, 8.7 months in S1, and 4.8 months in S2+. This analysis defines the clinical outcome associated with IDH-mutations in both the front-line and salvage AML treatment settings, and confirms that response rate and OS for both IDH-mutated and IDH wild-type AML patients is comparable. This provides contemporary data to be used for comparison with results of novel investigational (e.g., selective IDH inhibitor) strategies.
Effecf of EDTA on the Preimplantation Development of Mouse Embryos Fertilized in vitro (1985)

体外受精由来マウス胚の培養では,ある種の近交系間のF1卵子に由来する胚以外は胚盤胞への発生率が低く,多くの胚が2細胞期で発生を停止する,本研究は,この点を改善するために培地へのEDTA添加の効果について検討した.またEGTAの影響も検査した.ICRの精巣上体精子を用いて体外受精を行ない,授精後6時間に前核期の胚をキレート試薬を含むWhitten培地へ移し換え,さらに114時間培養を続けた.ICR卵子由来胚の発生は,2.5-500μM EDTAの存在下で促進された.とくに20-100μMの濃度では90%以上の胚が胚盤胞へ発生した.一方,EDTAを含まない培地における胚盤胞への発生率は31%であった.F1卵子由来胚ではEDTAの有無にかかわらず90%以上が胚盤胞へ発生した.EDTAは,ICR卵子由来胚に対して授精後12時間までに添加された場合に効果が著しく胚盤胞への発生率は80%以上に達した.また授精後6時間から18時間EDTAで処理した場合,発生率が70%以上を示した.EGTAは胚の発生に対して効果を示さなかった,これらのことから,EDTAは授精後12時間から24時間までの初期胚に対して顕著に作用し,4細胞期以降への発生を促していることが知られた.
Der Konvoi (2000)

Am nächsten Morgen waren wir gerade damit fertig, unsere Sachen wieder sorgfältig in den Rover zu stauen, als Hans und Helmut mit triumphierendem Jubeln und Hupen in ihrem VW-Bus angeprescht kamen. Die Freude war ansteckend, und wir alle lachten bei dem Gedanken, wieder unterwegs zu sein. Geoff und ich sprangen in den Rover, und wir rasten Hals über Kopf, Stoßstange an Stoßstange in die Stadt zurück.
Massive MIMO systems with hardware-constrained base stations (2014)

Massive multiple-input multiple-output (MIMO) systems are cellular networks where the base stations (BSs) are equipped with unconventionally many antennas. Such large antenna arrays offer huge spatial degrees-of-freedom for transmission optimization; in particular, great signal gains, resilience to imperfect channel knowledge, and small inter-user interference are all achievable without extensive inter-cell coordination. The key to cost-efficient deployment of large arrays is the use of hardware-constrained base stations with low-cost antenna elements, as compared to today's expensive and power-hungry BSs. Low-cost transceivers are prone to hardware imperfections, but it has been conjectured that the excessive degrees-of-freedom of massive MIMO would bring robustness to such imperfections. We herein prove this claim for an uplink channel with multiplicative phase-drift, additive distortion noise, and noise amplification. Specifically, we derive a closed-form scaling law that shows how fast the imperfections increase with the number of antennas.
Prognostic Techniques for Semiconductor Failure Modes (2000)

Semiconductor reliability issues are beginning to emerge as a major impediment to long term reliability of critical systems such as Internet routers, ATM machines, and Automotive/Aerospace fly-by-wire systems. Semiconductors have certain defined failure modes that can contribute to end-of-life failures. These modes include time-dependent dielectric breakdown of the gate oxide (TDDB), hot carrier damage, and metal migration. All of these common failure modes are far worse at geometries below 0.25µ. Fortunately, there are methods proposed that counteract these common failure modes. This paper surveys the problems involved, and recommends a methodology for the inclusion of pre-calibrated prognostic cells that can be co-located with a host circuit to provide an “early-warning” of a system failure, so that appropriate corrective action can be taken.
Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase (2010)

In vivo studies suggest that replication forks are arrested by encounters with head-on transcription complexes. Yet, the fate of the replisome and RNA polymerase (RNAP) after a head-on collision is unknown. We found that the Escherichia coli replisome stalls upon collision with a head-on transcription complex, but instead of collapsing, the replication fork remains highly stable and eventually resumes elongation after displacing the RNAP from DNA. We also found that the transcription-repair coupling factor Mfd promotes direct restart of the fork after the collision by facilitating displacement of the RNAP. These findings demonstrate the intrinsic stability of the replication apparatus and a previously unknown role for the transcription-coupled repair pathway in promoting replication past a RNAP block.
Conformational analysis of the tumor-associated carbohydrate antigen 19-9 and its Lea blood group antigen component as related to the specificity of monoclonal antibody CO19-9. (1990)

A structural comparison between the synthetic, tumor-associated 19-9 tetrasaccharide, NeuAc alpha 2----3Gal beta 1----3GlcNAc(4----1 alpha Fuc)-O(CH2)8CO2CH3 and its Lea blood group antigen component, Gal beta 1----3GlcNAc(4----1 alpha Fuc)-O(CH2)8CO2CH3 was carried out by two-dimensional 1H NMR spectroscopy and hard-sphere energy calculations. Significant chemical shift differences between the two molecules were detected only for protons at or near the linkage site of NeuAc to the Lea trisaccharide core. Coupling constants for the ring protons of both molecules did not suggest major deviation from the 4C1 chair conformation for Gal and GlcNAc, the 1C4 conformation for Fuc, or the 2C5 conformation for NeuAc. Two-dimensional nuclear Overhauser enhancement experiments revealed through-space, inter-proton interactions that corresponded to some extent with those predicted by diffraction data and hard-sphere energy minimization programs for both saccharides. However, a significant number of interactions did not obey the distance dependence predicted from a rigid structure model. These data suggest that, while the average conformation of the 19-9 antigen's Lea core may be invariant to NeuAc alpha 2----3Gal linkage, the dynamics of the Lea trisaccharide are altered upon sialylation. Data also indicate that the terminal NeuAc linkage is more flexible than the inter-residue bonds of the core trisacharide. This analysis, in combination with the fact that the monoclonal anti-19-9 antibody CO 19-9 does not cross-react with the Lea antigen, provides evidence in favor of NeuAc as an epitope-creating unit involved directly at the antibody binding site. However, given the possible role of variable dynamics in epitope formation, these results do not preclude crucial roles in antibody recognition for regions on the 19-9 antigen that are distanced from NeuAc.
Nucleotide sequence of the surface exclusion genes traS and traT from the IncF0 lac plasmid pED208 (1986)

pED208 is a 90-kilobase conjugative plasmid belonging to the incompatibility group IncF0 lac. The surface exclusion system from this plasmid was cloned and sequenced, and two genes demonstrated exclusion ability. traS encoded a 186-amino-acid hydrophobic protein which, when transcribed from a vector promoter, caused exclusion of pED208. The product of traT (TraTp) was a 245-residue protein which was highly expressed independently of a vector promoter in Escherichia coli minicells. The TraTp from pED208 was homologous with traT products from the IncF plasmids R-100 and F (80% homology), but recombinants containing the pED208 surface exclusion system excluded F poorly.
Videos as Space-Time Region Graphs (2018)

How do humans recognize the action "opening a book" ? We argue that there are two important cues: modeling temporal shape dynamics and modeling functional relationships between humans and objects. In this paper, we propose to represent videos as space-time region graphs which capture these two important cues. Our graph nodes are defined by the object region proposals from different frames in a long range video. These nodes are connected by two types of relations: (i) similarity relations capturing the long range dependencies between correlated objects and (ii) spatial-temporal relations capturing the interactions between nearby objects. We perform reasoning on this graph representation via Graph Convolutional Networks. We achieve state-of-the-art results on both Charades and Something-Something datasets. Especially for Charades, we obtain a huge 4.4% gain when our model is applied in complex environments.
Test metrics for analog parametric faults (2003)

This paper first summarizes the complete range of analog defects and resultant faults. A complete set of metrics is then derived for measuring the quality of analog tests. The probability-based equations for fault coverage, defect level, yield coverage, and yield loss are self-consistent, and consistent with existing equations for digital test metrics. We introduce the concept of partial coverage, show that it is inherent to analog testing, and show that coverage cannot be calculated without knowing the performance specifications for a circuit, as well as the process parameter distributions. Practical methods for calculating probabilities are discussed, and simple, illustrative examples given.