gebhart/patrepeval huggingface dataset:
How To Select PDC Bit for Optimal Drilling Performance (2007)

Abstract Selecting bit when you have multiple bit vendors giving their proposal can be a challenge for the operator. To justify the bit selection can be hard for the drilling engineer in a multiple vendor situation. The purpose of this paper is to show a systematic approach on how to select PDC bit based on quantitative measure by using a simple scorecard. When the drilling organization has agreed on the overall drilling objective for the well a scorecard is used as decision criteria for selecting bits. To quantify the input for each bit a drilling simulator was used. The simulator can, based on a rock strength prognosis for a well, predict the rate of penetration and bit wear for each bit based on the bit design. For other criteria which are more difficult to obtain e.g. ability to create dog leg a qualitative ranking was used. In the two field examples shown from the North Sea the method has worked well to give a reliable and transparent bit selection method. Using a scorecard also reduced the ambiguity among the bit company representatives on how the selection process was done.
High-Efficiency Broadband Anomalous Reflection by Gradient Meta-Surfaces (2012)

We combine theory and experiment to demonstrate that a carefully designed gradient meta-surface supports high-efficiency anomalous reflections for near-infrared light following the generalized Snell's law, and the reflected wave becomes a bounded surface wave as the incident angle exceeds a critical value. Compared to previously fabricated gradient meta-surfaces in infrared regime, our samples work in a shorter wavelength regime with a broad bandwidth (750-900 nm), exhibit a much higher conversion efficiency (∼80%) to the anomalous reflection mode at normal incidence, and keep light polarization unchanged after the anomalous reflection. Finite-difference-time-domain (FDTD) simulations are in excellent agreement with experiments. Our findings may lead to many interesting applications, such as antireflection coating, polarization and spectral beam splitters, high-efficiency light absorbers, and surface plasmon couplers.
The use of a membrane filtration device to form dried plasma spots for the quantitative determination of guanfacine in whole blood (2012)

The described work demonstrates proof-of-principle using membrane sample preparation techniques to form DPS samples from whole blood for subsequent bioanalysis by LC/MS/MS. This approach has the potential to eliminate the hematocrit issues from the current controversy surrounding validation of DBS assays.
Augmentation of anti-tumor immunity by adoptive T-cell transfer after allogeneic hematopoietic stem cell transplantation (2012)

Allogeneic hematopoietic stem cell transplantation (HCT) is currently the standard of care for most patients with high-risk acute leukemias and some other hematologic malignancies. Although HCT can be curative, many patients who undergo allogeneic HCT will later relapse. There is, therefore, a critical need for the development of novel post-HCT therapies for patients who are at high risk for disease recurrence following HCT. One potentially efficacious approach is adoptive T-cell immunotherapy, which is currently undergoing a renaissance that has been inspired by scientific insight into the key issues that impeded its previous clinical application. Translation of the next generation of adoptive T-cell therapies to the allogeneic HCT setting, using donor T cells of defined specificity and function, presents a unique set of challenges and opportunities. The challenges, progress and future of adoptive T-cell therapy following allogeneic HCT are discussed in this review.
Weak and strong synchronization of chaos (1996)

It is shown that synchronization in unidirectionally coupled chaotic systems develops in two stages as the coupling strength is increased. The first stage is characterized by a weak synchronization, i.e., a response system subjected to a driving system undergoes a transition and exhibits a behavior completely insensitive to initial conditions. Further increase of the coupling strength causes the dimension decrease of the overall dynamics and leads finally to a strong synchronization. In this stage, the dimension of the strange attractor in the full phase space of the two systems saturates to the dimension of the driving attractor.
Inherited Ateliotic Dwarfism in Mice: Characteristics of the mutation, little, on Chromosome 6 (1976)

A new autosomal recessive mutation in the mouse, little (lit), has been shown to be located on Chromosome 6. The mutation in the homozygous state causes ateliotic dwarfism that is first detected at 15 days of age by decreased body weight. Long bone lengths are significantly reduced. Skull width, however, is not affected. Female little mice are fully fertile; they may lose their first litters. Although most of the little males sire one or two litters, they rarely sire a third litter. Analysis of pituitary extracts electrophoresed on acrylamide gels reveal a significant reduction of the two anterior pituitary hormones, GH and PRL, in both male and female little mice. Because the little mouse shares a number of similarities with the human ateliotic dwarfism, isolated growth hormones deficiency type I, it may be a useful animal model for this inherited human growth disorder.
Superconductivity Above 100 K in Tl-Pb-Ca-R-Sr-Cu-O System (1990)

Abstract Bulk superconductivity with zero resistance temperature up to 108 K in Tl0.5Pb0.5Ca0.8A0.2Sr2Cu2 oxides (A = Y and lanthanides La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) was achieved. For Tl0.5Pb0.5Ca0.9B0.1Sr2Cu2Oy with B = Ce and mischmetal, superconducting transition temperatures were found to be 95 K and 101 K, respectively. Both powder x-ray diffraction profiles and electron diffraction results indicate that each monophasic sample crystallizes in the YBa2CU3O7-x-like tetragonal structure with space group P4/mmm. Magnetic property studies evidenced the coexistence of superconductivity and paramagnetism in magnetic rare-earth element containing compounds.
Gassing of Liquid Dielectrics under Electrical Stress (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGassing of Liquid Dielectrics under Electrical StressHarold Basseches and D. A. McLeanCite this: Ind. Eng. Chem. 1955, 47, 9, 1782–1794Publication Date (Print):September 1, 1955Publication History Published online1 May 2002Published inissue 1 September 1955https://pubs.acs.org/doi/10.1021/ie50549a027https://doi.org/10.1021/ie50549a027research-articleACS PublicationsRequest reuse permissionsArticle Views71Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Efficacy of multistrain direct-fed microbial and phytogenetic products in reducing necrotic enteritis in commercial broilers (2009)

Our laboratory is evaluating the efficacy of direct-fed microbials (DFM) and phytogenic products to control Clostridium perfringens, a gram-positive organism associated with decreased performance and morbidity and mortality associated with necrotic enteritis, as well as some recent human food safety issues. Three experiments were conducted to evaluate a DFM (PoultryStar) and a phytogenic product (PEP125), which were administered to birds from day of hatch until termination (d 25) via the drinking water or through supplementation to a wheat-corn diet, respectively. Each experiment contained a nonchallenged negative control and a positive control wherein birds were immunocompromised with a 10x dosage of infectious bursal disease vaccine at 14 d of age and subsequently gavaged with C. perfringens (10(7) cfu/mL) daily for 3 consecutive days starting on d 17. Intestinal lesions, mortality, and log10 values of C. perfringens in the probiotic and phytogenic treatment groups were found to be lower (P<0.05) than those observed in the positive controls. These experiments suggest that the DFM and the phytogenic product could be used as potential alternatives to help control C. perfringens and necrotic enteritis.
Pilot Assignment and Channel Estimation via Deep Neural Network (2018)

In orthogonal frequency division multiplexing (OFDM) systems, channel estimation is by far the most important operation in the receiver to ensure the accurate detection and decoding. Over the years, pilot-aided channel estimation has been widely used for this purpose. In open-loop systems, since there is no feedback link between the transmitter and receiver, an approach based on the equi-spaced pilot assignment has been widely employed. In this paper, we propose a closed-loop non-uniform pilot allocation strategy based on deep neural network (DNN) technique. From the numerical evaluations, we show that the proposed autoencoder-based pilot allocation technique outperforms conventional approaches by a large margin, demonstrating its ability to learn the statistical characteristics of the wireless channel.
Design and Implementation for APP of Chinese-English Inquiry Based on Android (2015)

In order to make the users to obtain more accurate,rapid and comprehensive information which they want to query,the author attempts to design and realize an APP of Chinese-English query based on Android. It is mainly constituted of the input module,Chinese character selection module and the display module. Through the application and usage of Youdao API,it will achieve Chinese-English translation and display to optimally meet the user's Chinese or English information management's demand.
1984 Continental Mark VII/Lincoln Continental Electronically-Controlled Air Suspension (EAS) System (1984)

<div class="htmlview paragraph">This paper describes the Electronic Air Suspension (EAS) System developed by Ford Motor Company. Design trade-offs between load-carrying capacity necessary with conventional steel spring suspension systems and riding comfort are avoided when today's microcomputer technology is combined with a leveling air spring suspension. An electric air compressor with regenerative air dryer, three electronic “Hall Effect” height sensors, four air springs with integral solenoids, and a control module with a single chip microcomputer are the key EAS System components discussed.</div>
Feature-Based Prediction of Trajectories for Socially Compliant Navigation (2012)

Mobile robots that operate in a shared environment with humans need the ability to predict the movements of people to better plan their navigation actions. In this paper, we present a novel approach to predict the movements of pedestrians.
Motoric Cognitive Risk Syndrome and the Risk of Dementia (2012)

A motor-based MCR syndrome provides a clinical approach to identify individuals at high risk for dementia, especially vascular dementia, to target for further investigations and who may benefit from preventive interventions.
Stateful Inspection firewall session table processing (2005)

Stateful Inspection is a key technology to network devices such as routers and firewalls. Existed session table architectures of Stateful Inspection devices store all session information in a single entry, which causes high time cost of session table timeout processing. In this paper we present a new architecture which divides a session entry into two parts, and designs different data structures for each other. The new architecture can improve the performance of session table greatly. A new PATRICIA algorithm is proposed to organize session table, which is proved to be an optimal 2-ary trie for fixed-length match. An ASIC is implemented for the architecture and corresponding algorithms. Both theoretical and experimental results show that the new architecture has better performance than existed architectures, and can work well in Gigabit Ethernet network.
Biological effects of PEA3 expression in HER-2/neu-overexpressing human cancer cells and the molecular mechanisms of PEA3-mediated transcriptional repression on HER-2/ neu (1998)

HER-2/neu is a receptor tyrosine kinase highly homologous with epidermal growth factor receptor. Overexpression and/or amplification of HER-2/neu has been implicated in the genesis of a number of human cancers, especially breast and ovarian cancers. Transcriptional upregulation has been shown to contribute significantly to the overexpression of this gene. Studies on the transcriptional regulation of HER-2/neu gene are important for understanding the mechanism of cell transformation and developing the therapeutic strategies to block HER-2/neu-mediated cancers. PEA3 is a DNA binding transcriptional factor and its consensus sequence exists on the HER-2/neu promoter. To examine the role of PEA3 in HER-2/neu expression and cell transformation, we transfected PEA3 into the human breast and ovarian cancer cells that overexpress HER-2/neu and showed that PEA3 dramatically represses HER-2/neu transcription. PEA3 suppresses the oncogenic neu-mediated transformation in mouse fibroblast NIH 3T3 cells. Expression of PEA3 selectively blocks the growth of human cancer cells that overexpress HER-2/neu and inhibits their colony formation. It does not occur in the cancer cells expressing basal level of HER-2/neu. Further studies in the orthotopic ovarian cancer model demonstrated that expression of PEA3 preferentially inhibits growth and tumor development of human cancer cells that overexpress HER-2/neu, the tumor-bearing mice survived significantly longer if treated by injection of the PEA3-liposome complex intraperitoneally. Immunoblotting and immunohistochemical analysis of the tumor tissues indicated that PEA3 mediates the tumor suppression activity through targeting HER-2/neu-p185. Thus, PEA3 is a negative regulator of HER-2/neu gene expression and functions as a tumor suppressor gene in the HER-2/neu-overexpressing human cancer cells. The molecular mechanisms of PEA3 mediated transcriptional repression were investigated. PEA3 binds specifically at the PEA3 site on HER-2/neu promoter and this promoter-binding is required for the PEA3 mediated transcriptional repression. Mutation of the PEA3 binding site on HER-2/neu promoter causes decreased transcriptional activity, indicating that the PEA3 binding site is an enhancer-like element in the HER-2/neu-overexpressing cells. We therefore hypothesized that in the HER-2/neu-overexpressing cells, PEA3 competes with a transactivator for binding to the PEA3 site, preventing the putative factor from activating the transcription of HER-2/neu. This hypothesis was supported by the data which demonstrate that PEA3 competes with another nuclear protein for binding to the HER-2/neu promoter in vitro, and expression of a truncated protein which encodes the DNA binding domain of PEA3 is sufficient to repress HER-2/neu transcription in the HER-2/neu-overexpressing human cancer cells.
Signaling of Cell Fate Decisions by <i>CLAVATA3</i> in <i>Arabidopsis</i> Shoot Meristems (1999)

In higher plants, organogenesis occurs continuously from self-renewing apical meristems. Arabidopsis thaliana plants with loss-of-function mutations in the CLAVATA (CLV1, 2, and 3) genes have enlarged meristems and generate extra floral organs. Genetic analysis indicates that CLV1, which encodes a receptor kinase, acts with CLV3 to control the balance between meristem cell proliferation and differentiation. CLV3 encodes a small, predicted extracellular protein. CLV3 acts nonautonomously in meristems and is expressed at the meristem surface overlying the CLV1 domain. These proteins may act as a ligand-receptor pair in a signal transduction pathway, coordinating growth between adjacent meristematic regions.
De compañeros de armas a “suizos vendidos”. Las alternativas de la emigración político-militar argentina en el Estado Oriental del Uruguay (1838-1846) (2019)

El presente artículo analiza las vías de inserción de la denominada “emigración argentina” opositora a Juan Manuel de Rosas en fuerzas de guerra y agrupaciones políticas de Montevideo y su hinterland rural entre 1838 y 1846, y el modo en que ese proceso, pleno de tensiones, impactó en la reconfiguración de los imaginarios culturales y “partidos” locales. A partir de un análisis cuantitativo sobre el número de militares emigrados, el trabajo postula que la construcción de dos oficialidades rioplatenses segmentadas, una “argentina” y otra “oriental”, fue en realidad un proceso lento y conflictivo que a mediados del siglo XIX todavía distaba de completarse.
Efficacy of an infectious hematopoietic necrosis (IHN) virus DNA vaccine in Chinook Oncorhynchus tshawytscha and sockeye O. nerka salmon (2005)

The level of protective immunity was determined for Chinook Oncorhynchus tshawytscha and sockeye/kokanee salmon (anadromous and landlocked) O. nerka following intramuscular vaccination with a DNA vaccine against the aquatic rhabdovirus, infectious hematopoietic necrosis virus (IHNV). A DNA vaccine containing the glycoprotein gene of IHNV protected Chinook and sockeye/kokanee salmon against waterborne or injection challenge with IHNV, and relative percent survival (RPS) values of 23 to 86% were obtained under a variety of lethal challenge conditions. Although this is significant protection, it is less than RPS values obtained in previous studies with rainbow trout (O. mykiss). In addition to the variability in the severity of the challenge and inherent host susceptibility differences, it appears that use of a cross-genogroup challenge virus strain may lead to reduced efficacy of the DNA vaccine. Neutralizing antibody titers were detected in both Chinook and sockeye that had been vaccinated with 1.0 and 0.1 pg doses of the DNA vaccine, and vaccinated fish responded to viral challenges with higher antibody titers than mock-vaccinated control fish.
Studies with 2-arylhydrazono-3-oxopropanals: Routes for the synthesis of pyridazine-3,4-dicarboxylate and 3,5-diaroyl pyrazoles (2009)

The title compounds 3a-j were synthesized via coupling of enaminones 2a-d with aromatic diazonium salts. The reaction of 3b-f,h-j with dimethyl acetylenedicarboxylate and triphenylphosphine afforded dimethyl 2-aryl-6-aroyl-2,3-dihydropyridazine-3,4-dicarboxylates 7b-f,h-j. . The reaction of 3b,d,f,g with phenacyl bromide afforded 3-aroyl-5-benzoylpyrazoles 9b,d,f,g.,while compound 3i condensed with benzoylacetonitrile to yield pyridazin-6-imine 11.Reaction of 3c-e,h,j with p-toluidine yielded the enamineazo 12c-e,h,j. The structures of 7b,d,i and 9b were confirmed by X-ray crystal structure determination.
A highly prevalent and genetically diversified <i>Picornaviridae</i> genus in South Asian children (2008)

Viral metagenomics focused on particle-protected nucleic acids was used on the stools of South Asian children with nonpolio acute flaccid paralysis (AFP). We identified sequences distantly related to Seneca Valley virus and cardioviruses that were then used as genetic footholds to characterize multiple viral species within a previously unreported genus of the Picornaviridae family. The picornaviruses were detected in the stools of >40% of AFP and healthy Pakistani children. A genetically diverse and highly prevalent enteric viral infection, characteristics similar to the Enterovirus genus, was therefore identified substantially expanding the genetic diversity of the RNA viral flora commonly found in children.
Analysis and characterization of P-N junction diode switching (1964)

A new charge control model of a p-n junction diode is introduced in which the reverse current i <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">R</inf> as well as the forward current I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F</inf> are related to the charge <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> stored in the base region by time constants τ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">R</inf> and τ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F</inf> , respectively. The reverse switching transient is analyzed for normal switching operation where a constant current phase (storage phase) and a decaying current phase exist, and for overdriven switching operation where no constant current phase exists. New switching time equations are derived. The equations are expressed in terms of measurable device parameters τ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F</inf> , τ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">R</inf> , and C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</inf> external circuit variables I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F</inf> and I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">R</inf> and an external circuit parameter R. The proposed model is applicable to p-n junction diodes of any type. Experimental results using various types of diodes are also reported. It is shown that the experimental results are in very good agreement with the theory.
o- und m-Phenylenbis(dichlorphosphan) - vielseitig verwendbare Synthesebausteine (2006)

Das vollständige Manuskript dieser Zuschrift erscheint in: Angew. Chem. Suppl. 1982, 1416. DOI: 10.1002/ange.198214160
Study of Mean- and Turbulent-Velocity Fields in a Large-Scale Turbine-Vane Passage (1980)

Laser-Doppler velocimetry was used to investigate the secondary flow in the endwall region of a large-scale turbine inlet-guide-vane passage. The mean and turbulent velocities were measured for three different test conditions. The different test conditions consisted of variations in the blade aspect ratio and the inlet boundary-layer thickness or all three cases, a passage vortex was identified and its development documented. The turbulent stresses within the vortex were found to be quite low in comparison with the turbulence in the inlet boundary layer.
Finding the inverse kinematics of manipulator arm using artificial neural network with lookup table (1997)

Neural networks were used to find the inverse kinematics of a two-link planar and three-link manipulator arms. The neural networks utilised were multi-layered perceptions with a back-propagation training algorithm. Because of the redundancy in the manipulators studied, this work used lookup tables for the different configurations of the manipulator arm.