gebhart/patrepeval huggingface dataset:
PLOT3D user's manual (1990)

PLOT3D is a computer graphics program designed to visualize the grids and solutions of computational fluid dynamics. Seventy-four functions are available. Versions are available for many systems. PLOT3D can handle multiple grids with a million or more grid points, and can produce varieties of model renderings, such as wireframe or flat shaded. Output from PLOT3D can be used in animation programs. The first part of this manual is a tutorial that takes the reader, keystroke by keystroke, through a PLOT3D session. The second part of the manual contains reference chapters, including the helpfile, data file formats, advice on changing PLOT3D, and sample command files.
Studies on the biotransformation of ketamine. II—quantitative significance of theN-demethylation pathway in ratsin vivo determined by a novel stable isotope technique (1989)

In order to determine the fraction of an intravenous bolus dose of ketamine which is metabolized in vivo to the corresponding N-desmethyl compound, norketamine, a novel stable isotope technique was developed and applied to a study in rats. Co-injection of equimolar amounts of deuterium-labeled ketamine and unlabeled norketamine to four animals, followed by gas chromatographic/mass spectrometric analysis of both the administered compounds and deuterium-labeled norketamine in plasma, yielded pharmacokinetic data from which the fraction of the parent drug subjected to N-demethylation (fm) was calculated from AUC data to be 36.8 +/- 2.4%. It is concluded that this stable isotope co-administration technique represents a powerful approach to the determination of fm, in that the pharmacokinetics of the metabolite of interest, given as the preformed compound and generated in vivo, are determined simultaneously. This experimental design thus obviates the influence of time-dependent changes in metabolite clearance which may complicate the interpretation of studies performed using the classical cross-over design.
O discurso dissimulador das Folhas caídas (1999)

Este estudo toma como objeto as <strong>Folhas caídas</strong>, de Almeida Garrett, analisadas sob a ótica da dualidade confissão/simulacro do sentimento amoroso, que remete para a prática da ironia romântica e aponta para a modernidade da poesia garrettiana (no sentido de assumir o jogo da representação como forma de realizar e, simultaneamente, de questionar a criação poética). Para efetivar-se, a análise estabelece entre os poemas do conjunto relações que intentam evidenciar a constituição de um espaço dramático onde o eu-lírico se torna personagem e, através deum "monólogo em cena", manifesta a sua "confissão".
Hemoglobin Disorders (2003)

The recent announcement that sickle-cell anemia and thalassemia have been corrected by the transplantation of stem cells bodes well for the future of gene therapy in hemoglobinopathies. In Hemoglobin Disorders: Molecular Methods and Protocols, Ronald Nagel, MD, has assembled a collection of readily reproducible techniques essential to the continued advance of our molecular understanding of these diseases. The book's richly experienced authors detail methods utilizing a wide variety of the latest analytical techniques, including X-ray crystallography, high performance liquid chromatography, electrophoresis, and nuclear magnetic resonance. Additional methods are offered for prenatal diagnostic analysis, the DNA diagnosis of hemoglobin mutations, hemoglobin fluorescence, and the semisynthesis of hemoglobin. Each protocol includes an introduction explaining the basic science, step-by-step instructions for its successful execution, notes on pitfalls to avoid, and tips on how to employ it effectively with novel systems and conditions. State-of-the-art and highly practical, Hemoglobin Disorders: Molecular Methods and Protocols reviews all the basic topics and techniques in this critically important field, and offers today's most comprehensive set of proven protocols for successful experimental and clinical work on hemoglobin diseases
The relationship between time since registration and measured incidence rates in the General Practice Research Database (2005)

Reported incidence rates are highest in the first 3 months after registration with an UTS practice and decline to baseline over the first year, more quickly for acute conditions than chronic conditions. For patients who registered prior to UTS, incidence rates are near the baseline level at the start of follow-up.
Immunotoxin: A new tool for cancer therapy (2017)

Cancer is one of the main reasons of death in the most countries and in Iran. Immunotherapy quickly became one of the best methods of cancer treatment, along with chemotherapy and radiation. "Immunotoxin Therapy" is a promising way of cancer therapy that is mentioned in this field. Immunotoxins are made from a toxin attaching to an antibody target proteins present on cancer cells. The first-generation immunotoxins were made of a full-length toxin attached to whole monoclonal antibodies. But, these immunotoxins could bind to normal cells. DAB389IL2 was the first immunotoxin approved by the Food and Drug Administration. Current trends and researches are ongoing on finding proteins that in combination with immunotoxins have minimal immunogenicity and the most potency for target cell killing.
Characterization of polyamideamine‐epichlorohydrin (PAE) resin: Roles of azetidinium groups and molecular mass of PAE in wet strength development of paper prepared with PAE (2005)

Abstract Polyamideamine‐epichlorohydrin (PAE) resin is a crosslinked heteropolymer having cationic charges, and has been widely used as a wet strength agent of paper in the papermaking process. In this study, more accurate molecular mass values of PAE were determined by size exclusion chromatography attached with a multi angle laser light scattering detector (SEC‐MALS). The obtained weight average molecular mass ( M w ) values of commercial and laboratory‐made PAE samples were 1,140,000 and 494,000, respectively, and these values were much higher than those reported so far. SEC‐MALS analysis also revealed that PAE molecules had highly crosslinked structures and extremely wide molecular mass distributions. Molecular mass values and content of 3‐hydroxy‐azetidinium (AZR) groups in PAE and PAE intermediates during the course of PAE synthesis were also determined by the SEC‐MALS and 1 H NMR methods, and the relationships between these values and the wet strength development of handsheets prepared with these PAE samples were studied. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2249–2255, 2005
Fungal flora of the digestive tract of Panstrongylus megistus (Reduviidae) used for experimental xenodiagnosis of Trypanosoma (Schizotripanum) cruzi Chagas, 1909. (2001)

A survey of the fungi isolated from the digestive tract of Panstrongylus megistus (insects vectors from Chagas' disease) used on xenodiagnosis was carried out. Two hundred and fourteen fungal strains were isolated from 180 nymphs. Aspergillus and Penicillium were the most predominant genera and some of their species were new records concerning insects. A great reduction in the fungal population was observed in the material that was positive for Trypanosoma cruzi.
Common mode and differential mode characteristics of AC motor for EMC analysis (2016)

In Adjustable Speed Drives (ASD), high frequency parasitic currents cause several unexpected problems, such as premature deterioration of motor winding insulation and ball bearings. In order to understand and to mitigate electromagnetic disturbance it is necessary to use a precise model of the PWM inverter, the energy cable and the AC motor. In this paper, an equivalent circuit of the three phase induction motor for high frequencies is presented. The proposed model details separately the common mode and differential mode characteristics of the AC motor. The high-frequency model has been obtained by means of a frequency domain analysis using an experimental setup and a MATLAB model. In order to verify extracted parameters, in-circuit impedance measurements for the AC motor using an Agilent 4294A Impedance Analyzer are done. The Measured results basically verify the extracted data, while the discrepancy between measured results and simulated results is also analysed.
Real‐Time Liquid Crystal pH Sensor for Monitoring Enzymatic Activities of Penicillinase (2009)

Abstract A liquid crystal (LC)‐based pH sensor for real‐time monitoring of changes in localized pH values near a solid surface is reported, along with its application for the detection of enzymatic activities. It is found that 4‐cyano‐4′‐pentylbiphenyl (5CB), when doped with 4′‐pentyl‐biphenyl‐4‐carboxylic acid (PBA), shows a bright‐to‐dark optical response to a very small change in pH (from 6.9 to 7.0). The pH‐driven optical response can be explained by using orientational transitions of 5CB induced by the protonation and deprotonation of PBA at the aqueous/LC interface. Because of its high pH sensitivity, the LC‐based sensor is further exploited for monitoring local pH changes resulting from enzymatic reactions. As a proof of concept, the hydrolysis of penicillin G by surface‐immobilized penicillinase is monitored using the system, even when the concentration of penicillin G is as low as 1 n M . This type of LC‐based sensor may find potential utilities in high‐throughput screening of enzyme substrates and enzyme inhibitors.
Adaptive Grid Refinement Improves Gas Injection Modeling (2016)

Abstract This paper introduces a new method to create adaptive mesh refinement and coarsening in compositional reservoir simulation. The methodology targets individual cells for refinement based on forecasted compositional fronts calculated using streamlines and the analytical convection-dispersive transport equation. Quadtree decomposition determines the optimal spatial discretization across the simulation grid using dynamic and static reservoir properties. Application of the new approach results in improved computational performance and better representation of complex fluid behavior. Current dynamic gridding implementations have rigid schemes, posing two major limitations: cell refinement size is a pre-determined input value and compositional maps from the previous time step define the refinement region. This solution leads to suboptimal modeling due to time-lagging refinement and lack of grid adaptability in heterogeneous reservoirs and/or fast-moving compositional fronts. The new methodology overcomes these limitations by combining streamline and particle trajectory to forecast the injection front location and adapt grid sizes in advance. Tracking compositional variations starts by calculating fluxes for all cells using the finite-difference solution. Next, Pollock's tracing method allows reducing the 3-dimensional model into a series of 1-dimensional streamlines, while the convection-dispersive equation forecasts future compositions, shape, and location of injection front along each streamline trajectory. Finally, quadtree decomposition analyzes the homogeneity of dynamic and/or static properties (e.g., composition, pressure, permeability, facies) to determine if a volume can be represented by a single gridblock or if it requires refinement to preserve spatial details. Grid discretization is dynamic over time, refining cells requiring high-resolution and/or coarsening those with low variation. A mechanistic model with CO2 injection served to evaluate the methodology. The fluid was modeled with five pseudo-components and the Peng-Robison equation of state with volume translation to improve volumetric predictions. The new approach reduced the total number of cells required to model miscible injection by continuously creating adaptive grids that represent the advancement and shape of the injection front. Results showed a reduction in computational cost between 30-63% over a static fine grid without compromising the representation of compositional mixing phenomena and production forecast.
Posttranscriptional control of glutathione S-transferase pi gene expression in human breast cancer cells. (1992)

The glutathione S-transferase pi gene (GST pi) is highly expressed in estrogen receptor negative (ER-) but not expressed in ER+ human breast cancer cell lines. To define regulatory mechanisms of GST pi gene expression, we analyzed both the activity of the GST pi promoter and the posttranscriptional fate of GST pi RNA sequences in three ER+ and three ER- breast cancer cell lines. Expression of a transiently transfected CAT reporter gene driven by the GST pi promoter and 2203 nucleotides of 5'-flanking sequences were similar in all six cell lines regardless of ER status. Endogenous GST pi transcription rates in nuclei isolated from ER- cells were quite low despite high steady state levels of cytoplasmic mRNA. Furthermore, the endogenous GST pi gene was transcribed in ER+ nuclei at rates similar to those obtained in ER- nuclei. We determined the stabilities of mRNAs transcribed from the endogenous GST pi gene (ER- cells) and from a stably transfected GST pi cDNA expression vector (ER+ and ER- cells). The endogenous GST pi mRNA was extraordinarily stable in ER- cells. Comparisons between transfected ER+ and ER- cells revealed no significant differences in the stabilities of transfection-derived GST pi mRNA sequences. We conclude that GST pi mRNA stability contributes significantly to the high levels of cytoplasmic mRNA observed in ER- cells, but that the differential expression of GST pi in ER+ versus ER- cells is governed by other posttranscriptional processes.
Morphology of Evaporated Multiblock Copolymer Membranes Studied by Molecular Dynamics Simulations (2004)

We present extensive simulations modeling the casting of multiblock polymer films by evaporation. The domain structure of the resulting film is strongly affected by varying the relative stiffness of the coblocks. The morphology changes from a bicontinuous lamellar phase when both blocks are flexible to a small-scale phase-separated phase with isolated domains as the stiffness of one of the blocks increases. As the relative stiffness of the blocks changes, the rate of evaporation, interfacial width, and morphology of the system changes. The findings can be used to tailor membrane morphology of interest to fuel-cell applications where the morphology is important for proton conduction.
Wide Bite Angle Diphosphines:  Xantphos Ligands in Transition Metal Complexes and Catalysis (2001)

The reactivity of organotransition metal complexes is dependent on the ligand environment of the metal. This Account describes the development and application of new diphosphine ligands, designed to induce large P-M-P angles in transition metal complexes. Aided by computational chemistry, a homologous range of diphosphines based on rigid heterocyclic aromatic backbones of the xanthene-type with natural bite angles of approximately 100-134 degrees have been developed. The special structure of the ligands has an enormous impact on stability and reactivity of various transition metal complexes. Highly active and selective catalysts have been obtained by influencing this reactivity.
Light Sources for WDM Passive Optical Networks (2007)

This paper reviews and analyzes various light source schemes for high speed WDM passive optical networks in terms of configuration, performance and cost, including self- seeding of reflective semiconductor optical amplifiers (RSOAs), carrier distribution, remote external seeding of Fabry-Perot laser diodes (FPLDs) and downlink carrier remodulation.
Inhibitory effect of alpha-fetoprotein on the binding of myasthenia gravis antibody to acetylcholine receptor. (1980)

The binding of myasthenia gravis antibody acetylcholine receptor (AcChoR) as measured in vitro by Radioimmunoassay with 125I-labeled alpha-bungarotoxin (alpha-BuTx), can be blocked by amniotic fluid, maternal serum, and umbilical cord serum. This inhibitory effect is due to alpha-fetoprotein present in high concentrations in amniotic fluid and serum, as shown by: (i) selective removal of several components from amniotic fluid and serum; (ii) selective addition of different components present in amniotic fluid and serum, including alpha-fetoprotein, to be radioimmunoassay; (iii) correlation between the inhibitory effect of both amniotic fluid and serum and between the amounts of alpha-fetoprotein they contain; (iv) blocking of the alpha-fetoprotein in vitro suggests a similar effect in vivo in pregnant women with myasthenia gravis. This effect may explain in part the variability in the development of neonatal myasthenia gravis in the babies, due to transplacental transfer of maternal anti-AcChoR antibody, only after delivery and only in the minority of the cases. It also may explain the appearnace of remissions in females with myasthenia gravis during the second and third trimesters of pregnancy. Similar phenomena observed during pregnancy in other autoimmune and immunopathogenic diseases also might be attributed to activity of alpha-fetoprotein.
Moving object trajectory estimation using an optical Fourier processor (1998)

A vision system that estimates the trajectory (velocity and direction) of moving targets in a 2D field at video frame rates has been developed and constructed. The system uses an optical Fourier processor to calculate the frequency domain representation of moving objects from which their trajectory is estimated using conventional electronic processing techniques. In a series of experiments, target velocities were estimated to within 4 percent of their actual value and direction was estimated to within 3 degrees.
<i>In Vitro</i> Antioxidant Activity of a Number of Plant Essential Oils and Phytoconstituents (2000)

Abstract The antioxidant capacity of the synthetic antioxidants BHA, BHT, pyrogallol and α-tocopherol, the essential oils from black pepper, clove, geranium, melissa, nutmeg, oregano and thyme and 33 phytoconstituents were assessed in vitro, using an antioxidant assay. All die compounds demonstrated antioxidant capacity superior to the water soluble α-tocopherol analogue Trolox with the exception of the essential oil melissa and the phytoconstituents aromadendrene, myrcene and nerol. Clove, oregano and thyme were exceptionally potent in this assay, comparable with the activities of both BHA and pyrogallol. Eugenol, carvacrol, and thymol similarly demonstrated an equivalent degree of activity. These phytoconstituents are the major components present in clove, oregano and thyme essential oils, respectively.
A stability of LCLS linac modulators (2012)

Information concerning to a stability of LCLS RF linac modulators is allocated in this paper. In general a “pulse-to-pulse” modulator stability (and RF phase as well) is acceptable for the LCLS commission and FEL programs. Further modulator stability improvements are possible and approaches are discussed based on our experimental results.
Chemical Distribution and Bonding of Lithium in Intercalated Graphite: Identification with Optimized Electron Energy Loss Spectroscopy (2011)

Direct mapping of the lithium spatial distribution and the chemical state provides critical information on structure-correlated lithium transport in electrode materials for lithium batteries. Nevertheless, probing lithium, the lightest solid element in the periodic table, poses an extreme challenge with traditional X-ray or electron scattering techniques due to its weak scattering power and vulnerability to radiation damage. Here, we report nanoscale maps of the lithium spatial distribution in electrochemically lithiated graphite using electron energy loss spectroscopy in the transmission electron microscope under optimized experimental conditions. The electronic structure of the discharged graphite was obtained from the near-edge fine structure of the Li and C K-edges and ab initio calculations. A 2.7 eV chemical shift of the Li K-edge, along with changes in the density of states, reveals the ionic nature of the intercalated lithium with significant charge transfer to the graphene sheets. Direct mapping of lithium in graphite revealed nanoscale inhomogeneities (nonstoichiometric regions), which are correlated with local phase separation and structural disorder (i.e., lattice distortion and dislocations) as observed by high-resolution transmission electron microscopy. The surface solid-electrolyte interphase (SEI) layer was also imaged and determined to have a thickness of 10-50 nm, covering both edge and basal planes with LiF as its primary inorganic component. The Li K-edge spectroscopy and mapping, combined with electron microscopy-based structural analysis provide a comprehensive view of the structure-correlated lithium intercalation in graphite and of the formation of the SEI layer.
Residential Building Construction: State-of-the-Art Review (2014)

This paper presents an overview of the most current topics of interest related to the field of housing and residential building construction. It addresses issues related to industry-wide residential construction trends, policies, innovative technology adoption, construction management, sustainability, energy efficiency, building science, and the need for education, especially regarding architectural concerns. The authors discuss several key technical aspects of residential building, such as structural concerns, building enclosures, and indoor environmental quality issues. Emphasis is placed on the need for renewed research and development efforts, outside-the-box thinking related to financial and investment structures for housing, improved models for adopting innovative technologies in residential construction, new construction management approaches, incorporation of more advanced building science in conjunction with advanced engineered features and architectural design, embracing green and sustainable design and construction, and consideration of the health of the occupants. The authors, who have varying specialties, identify critical issues that need more investment to support technical studies and developments as well as education, training, and awareness efforts.
SHORT NOTICES (1985)

Journal Article SHORT NOTICES Get access Francis and Clare: the Complete Works. Translated by R. J. ARMSTRONG and I. C. BRADY. Pp. xvi+256. (The Classics of Western Spirituality.) London: S.P.C.K., 1982. N.p. G. R. EVANS G. R. EVANS Search for other works by this author on: Oxford Academic Google Scholar The Journal of Theological Studies, Volume 36, Issue 1, April 1985, Pages 282-b–282, https://doi.org/10.1093/jts/36.1.282-b Published: 01 April 1985
Do Docks Make Trade?: The Case of the Port of Great Grimsby (1992)

This section of the journal is comprised of essays exploring the development of the port, the impact of British shipping abroad, as both a globally significant mode of transport and as a force for change within the business realm, and the rise and decline of shipbuilding industries throughout Britain, paying particular attention to Ulster and Northern Ireland, and the post-World War II period. Contributions come from Gordon Jackson; J. Forbes Munro; Robert G. Greenhill; Andrew Armitage; and Tony Slaven.