gebhart/patrepeval huggingface dataset:
Developmental regulation of the orphan receptor <i>COUP-TF II</i> gene in spinal motor neurons (1994)

Members of the steroid/thyroid hormone receptor superfamily are involved in the control of cell identity and of pattern formation during embryonic development. Chicken ovalbumin upstream promoter-transcription factors (COUP-TFs) can act as regulators of various steroid/thyroid hormone receptor pathways. To begin to study the role of COUP-TFs during embryogenesis, we cloned a chicken COUP-TF (cCOUP-TF II) which is highly homologous to human COUP-TF II. Northern analysis revealed high levels of cCOUP-TF II transcripts during organogenesis. Nuclear extracts from whole embryos and from embryonic spinal cords were used in electrophoretic mobility shift assays. These assays showed that COUP-TF protein is present in these tissues and is capable of binding to a COUP element (a direct repeat of AGGTCA with one base pair spacing). Analysis of cCOUP-TF expression by in situ hybridization revealed high levels of cCOUP-TF II mRNA in the developing spinal motor neurons. Since the ventral properties of the spinal cord, including the development of motor neurons, is in part established by inductive signals from the notochord, we transplanted an additional notochord next to the dorsal region of the neural tube in order to induce ectopic motor neurons. We observed that an ectopic notochord induced cCOUP-TF II gene expression in the dorsal spinal cord in a region coextensive with ectopic domains of SC1 and Islet-1, two previously identified motor neuron markers. Collectively, our studies raise the possibility that cCOUP-TF II is involved in motor neuron development.
Changes in 2,3-DPG Content and Oxygen Affinity inErythrocytes Stored at 4°C (1979)

The 2,3-DPG content of red blood cells increased within the first 24 h when fresh erythrocytes or whole blood were stored at 4 °C. This phenomenon was strongly pH dependent. The temporary increase in 2,3-DPG was scarcely observed below pH 7.4 or above pH 7.8. In the case of whole blood, the increase was observed in CPD blood but not in ACD blood. Similar results were obtained with erythrocytes suspended in saline, when its pH was adjusted to approximately 7.6. Plasma proteins were not essential for the increase in 2,3-DPG content. Extracellular oxygen levels were continually measured in erythrocyte suspensions in order to check the changes in oxygen affinity of hemoglobin without damaging the cells. Both extracellular oxygen levels and 2,3-DPG contents were simultaneously increased by keeping fresh erythrocytes at 4°C. Inhibition of glycolysis with sodium fluoride and monoiodoacetic acid indicated that the in vivo steady state of glycolysis in erythrocytes might be altered by chilling to make the rate of 2,3-DPG synthesis faster than that of 2,3-DPG decomposition.
Investigation the conductivity of carbon fiber composites focusing on measurement techniques under dynamic and static loads (2019)

Carbon fibers (CFs) have been e polymeric xtensively investigated in several applications because Carbon fibers have unique characteristics in comparison to other materials. CFs have superior qualities for example as high mechanical strength, Young's modulus, tenacity, and thermal conductivity when reinforced with other composites. Dynamic load measurements are highly conductive than static load measurements. Conductive carbon yarn fibers are much better than all other fiber structures in terms of conductivity. The conductivity of carbon fiber has proven that this is the best material for the aircraft industry because of its many advantages. This study project is systematic and provides the latest technology that uses the reformed conductivity of carbon fibers. The focus of the present study is a review of an assortment of studies related to conductive nanofibers. It has been established that a correlation exists among the factors that show a dynamic character in the uses adopted for these conductive nanofibers. This paper examines the morphology, structure and composition, electrical conductivity, and mechanical, and electrochemical attributes that inform the use of these conductive nanofibers which have enabled these fibers to be used in various applications.
Experimental Reconstruction of the Intrathoracic Trachea Using a New Prosthesis Made from Collagen Grafted Mesh (1994)

Intrathoracic tracheal replacement was performed in dogs using a tracheal prosthesis we had constructed from mesh. The prosthesis consists of Marlex mesh (polypropylene) reinforced with a continuous polypropylene spiral, and is grafted and coated with pig collagen (Types I and III). Complete surgical resection of the mediastinal trachea was performed in seven adult mongrel dogs. In 1 dog, a 4 tracheal ring segment (2 cm) was resected and replaced with a 3 cm prosthesis, and in 6 dogs, a 7 to 8 tracheal ring segment (4 cm) was resected and replaced with a 5 cm prosthesis. In the latter six dogs, a silicone tube was temporarily inserted into the replacement, and removed by bronchoscopy one month after surgery. In one dog that received a 4 cm replacement, we added omentopexy around the reconstructed trachea. The prostheses in all dogs were promptly infiltrated by surrounding tissue and incorporated by the host trachea. No dehiscence or air leakage was observed after surgery. Mild luminal stenosis was evident in one dog, and partial exposure of the mesh (ulceration) was observed in five dogs within an observation period of 3 to 26 months. However, in the dog that received omentopexy after tracheal reconstruction, no stenosis or ulceration was observed, and the luminal surface seemed lustrous even after 6 weeks. Formation of respiratory epithelium, which lined the prosthetic lumen, was seen to various degrees: in the 2 dogs killed 12 months and 26 months after surgery, confluent epithelization was confirmed histologically from the upper to the lower anastomosis of the prosthesis. The tracheal prosthesis is useful for the repair of intrathoracic tracheal defects and shows promise for clinical application with further investigation.
Rhizobium inoculant and seed-applied fungicide effects on field pea production (2002)

Field pea has been shown to benefit from the use of rhizobium inoculation and seed-applied fungicides under intensive production. The objective of this research was to determine the effect of seed- or soil-applied rhizobium (Rhizobium leguminosarum bv. viciae) inoculants and seed-applied fungicides on field pea (Pisum sativum “Carneval”) production on fields with no previous history of the crop. The study was conducted at seven locations in Saskatchewan in each of 2 yr. Fungicide treatments were Apron FL (metalaxyl), Apron FL + Thiram 75WP (dithiocarbamate) and an untreated check in 1997 and a fourth treatment, Thiram 75WP, was added in 1998. Rhizobium treatments were seed-applied liquid inoculant, soil-applied granular inoculant and a non-inoculated check. Inoculation with rhizobium increased nodulation (5 of 10 sites), seed yield (6 of 13 sites), and protein content (3 of 8 sites), but occasionally appeared to reduce emergence (3 of 14 sites). Granular inoculant had more beneficial effects than the liquid inoculant. Fungicide treatments had few positive effects on production, and occasionally negative effects such as reduced emergence. Interaction effects were rare between seed-applied fungicide and seed-applied liquid or soil-applied granular rhizobium inoculants, which indicated compatibility of these products. Variability in the effects of inoculant types and fungicides suggests that responses are dependent on local soil and environmental conditions. Key words: Apron (metalaxyl), Thiram (dithiocarbamate), Pisum sativum, zero tillage
OBSERVATIONS ON THE NESTS AND BEHAVIOUR OF SOME EURYGLOSSINE BEES (HYMENOPTERA: COLLETIDAE) (1969)

Abstract Nests of Euryglossa (Euryglossa) sp., Euryglossula chalcosoma (Cockerell), Brachyhesma perlutea (Cockerell), Xanthesma sp., Xanthesma furcifera (Cockerell), Euryglossina (Eury‐glossina) hypochroma Cockerell, Euryglossina (Turnerella) pulchra Exley, Pachyprosopis haematostoma Cockerell and Pachyprosopis indicans Cockerell are described for the first time. Euryglossina (Turnerella) pulchra appears to be parasitised by a species of Gasteruption (Hymenoptera: Gasteruptiidae) and Euryglossula chalcosoma and Xanthesma furcifera by species of Hyptiogaster (Hymenoptera: Gasteruptiidae). Males of Euryglossa (Euhesma) sp. and Euryglossa (Callohesma) sp. were found sleeping on low vegetation. Males of Euryglossina (Euryglossina) hypochroma spent nights and cool periods within the nests.
Sams Teach Yourself JavaServer Pages in 21 Days (2002)

Sams Teach Yourself JavaServer Pages in 21 Days offers a proven tutorial format to teach JSP in 21 example-driven lessons. This book is for Web publishing professionals migrating to JavaServer Pages for its ability to create dynamic, interactive Web sites and separate presentation from Java code running behind the scenes. The book starts by explaining the relationship between JSP and Java Servlets and the basics of JSP functions and features. You'll then learn how JSP handles data, interacts with Java components, tracks users, and more. Later chapters discuss debugging, working with databases, XSLT and XML, using the Struts framework from Apache, handling binary data like graphics, and deploying JSP applications. Each topic is illustrated with many working examples that the reader can understand and put to work immediately. Throughout the book the author provides pointers to upcoming developments in JSP 2, to ensure that you are prepared for changes in the new version.
Bismuth-zinc-niobate embedded capacitors grown at room temperature for printed circuit board applications (2006)

We fabricated metal-insulator-metal (MIM) thin film capacitors with Bi1.5Zn1.0Nb1.5O7 (BZN) dielectric films. The BZN films were deposited at room temperatures by pulsed laser deposition and annealed below 200°C which is compatible with the used polymer-based substrates. The dielectric constant of BZN films increases from 2 to 70, when they are annealed at 150°C, but still in amorphous phase. We found that a considerable portion of Bi metallic phase still remains in the as-deposited film. They turn into oxides upon annealing at &gt;120°C, causing the dramatic change of the dielectric properties. Amorphous BZN thin films exhibit superior dielectric characteristics, capacitance density of 150nF∕cm2, and leakage current less than 1μA∕cm2 at 5V. The MIM capacitors using amorphous BZN thin films will be a promising candidate for the PCB-embedded capacitors.
Restorer breeding in sweet pepper: Introgressing Rf allele from hot pepper through marker-assisted backcrossing (2015)

Lack of a strong and stable restorer-of-fertility (Rf) allele in sweet pepper (Capsicum annuum L.) has been a hurdle in commercial exploitation of cytoplasmic male sterility (CMS) system for cost-effective production of sweet pepper hybrid seeds. A known sequence characterized amplified region (SCAR) marker (CRF-S870) associated with a fertility restoration phenotype (Rf locus) in hot pepper was validated in a strong restorer hot pepper inbred line (AVPP9905). The CRF-S870 marker was successfully used in marker-assisted backcrossing (MAB) to transfer Rf allele from hot pepper line AVPP9905 to several sweet pepper genotypes. The fertility restoration ability of 21 BC4F2 sweet pepper plants obtained through marker-assisted backcrossing was found to be normal, as CMS based plants derived from the backcrossed male plants upon selfing produced a normal amount of fruit with sufficient selfed seeds. The development of restorer lines in sweet pepper is expected to open commercial exploitation of CMS hybrid technology in sweet pepper.
Network Analysis Identifies SOD2 mRNA as a Potential Biomarker for Parkinson's Disease (2014)

Increasing evidence indicates that Parkinson's disease (PD) and type 2 diabetes (T2DM) share dysregulated molecular networks. We identified 84 genes shared between PD and T2DM from curated disease-gene databases. Nitric oxide biosynthesis, lipid and carbohydrate metabolism, insulin secretion and inflammation were identified as common dysregulated pathways. A network prioritization approach was implemented to rank genes according to their distance to seed genes and their involvement in common biological pathways. Quantitative polymerase chain reaction assays revealed that a highly ranked gene, superoxide dismutase 2 (SOD2), is upregulated in PD patients compared to healthy controls in 192 whole blood samples from two independent clinical trials, the Harvard Biomarker Study (HBS) and the Diagnostic and Prognostic Biomarkers in Parkinson's disease (PROBE). The results from this study reinforce the idea that shared molecular networks between PD and T2DM provides an additional source of biologically meaningful biomarkers. Evaluation of this biomarker in de novo PD patients and in a larger prospective longitudinal study is warranted.
Rapid TLC and HPLC Quantification of Cucurbitacin C in Cucumber Cotyledons (1986)

Abstract Two rapid methods for estimating cucurbitacin C (Cuc C) in cucumber cotyledons are described. Both methods require a single cotyledon extracted with methanol. The filtered extract is injected into a C18 HPLC column with methanol-water (55:45) solvent, and quantitative estimates of Cuc C are obtained by UV detection at 254 nm. In the 2nd method, the extract is concentrated for spotting on silica gel TLC plates, the TLC plates are developed with ethylacetate : benzene (75:25), and visualized with vanillin-orthophosphate to give a semiquantitative estimate of Cuc C. The 2 methods are quick and suited for screening seedlings for cucurbitacin levels in segregating populations to select for cucumber beetle resistance and for nonbitter fruit.
The adaptive classical capacity of a quantum channel, or Information capacities of three symmetric pure states in three dimensions (2004)

We investigate the capacity of three symmetric quantum states in three real dimensions to carry classical information. Several such capacities have already been defined, depending on what operations are allowed in the protocols that the sender uses to encode classical information into these quantum states, and that the receiver uses to decode it. These include the C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,1</inf> capacity, which is the capacity achievable if separate measurements must be used for each of the received states, and the C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,∞</inf> capacity, which is the capacity achievable if joint measurements are allowed on the tensor product of all of the received states. We discover a new classical information capacity of quantum channels, the adaptive capacity C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,A</inf> , which lies strictly between the C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,1</inf> and the C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,∞</inf> capacities. The adaptive capacity allows the use of what is known as the LOCC (local operations and classical communication) model of quantum operations for decoding the channel outputs. This model requires each of the signals to be measured by a separate apparatus, but allows the quantum states of these signals to be measured in stages, with the first stage partially reducing their quantum states; measurements in subsequent stages may depend on the results of a classical computation taking as input the outcomes of the first round of measurements. We also show that even in three dimensions, with the information carried by an ensemble containing three pure states, achieving the C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,1</inf> capacity may require a positive operator valued measure (POVM) with six outcomes.
Heptulose Synthesis from Nonphosphorylated Aldoses and Ketoses by Spinach Transketolase (1971)

Abstract 1. The enzyme present in spinach leaves that catalyzes the transfer of a 2-carbon fragment from hydroxypyruvate to d-ribose, l-lyxose, d-xylose, and l-arabinose to form the corresponding free heptuloses was purified to near electrophoretic homogeneity and found to be identical with transketolase. The maximum velocity for the reaction of these pentoses with a saturating concentration of hydroxypyruvate was the same, whereas the Michaelis constants were different. The Michaelis constants were 45 mm for d-ribose, 55 mm for l-lyxose, 120 mm for l-arabinose, and 230 mm for d-xylose. It may thus be possible to account for the production of free heptuloses in plants which have been infiltrated with pentoses, without invoking the participation of phosphorylated pentose intermediates or of a new ligase. 2. Also serving as donors with transketolase when ribose was the acceptor were d-fructose and l-sorbose. When unlabeled d-sedoheptulose and ribose-5-3H were incubated with the enzyme, sedoheptulose-7-3H was formed, showing that sedoheptulose was also a donor. Moreover, 14C-gluco-heptulose was formed from sedoheptulose and l-arabinose-1-14C. 3. The molecular weight of transketolase was estimated as 100,000 ± 10,000 from gel filtration, electrophoresis in sodium dodecyl sulfate on polyacrylamide, and sedimentation equilibrium experiments.
Thermal and Conduction Properties of a PCL-biodegradable Gel Polymer Electrolyte with LiClO4, LiF3CSO3, and LiBF4 Salts (2007)

A biodegradable gel polymer electrolyte was prepared using Poly(e-caprolactone) as a polymer host and its electrochemical performance was evaluated. The biodegradable gel polymer electrolyte was produced by casting through dissolution of PCL in tetrahydrofuran (THF) with 5, 10, and 15% wt. of the propylene carbonate and several salt concentrations of LiClO 4 , LiF 3 CSO 3 , and LiBF 4 . The thermal behavior of the gel polymer electrolytes has shown that the addition of propylene carbonate as a plasticizer agent in the PCL promotes an increase in the disorder of the crystalline phase, decreasing the crystallinity degree. The glass transition temperature increased as the concentration of lithium salts was increased. The ionic conductivities of the PCL/10% PC to LiClO4, LiF 3 CSO 3 , and LiBF 4 with 12% wt at room temperature were about 2.26 x 10 -4 , 4 x 10 -5 , and 1.5 x 10 -7 S cm -1 , respectively. The conductivity enhancement with temperature can be understood in terms of a free-volume model. The biodegradable gel polymer electrolyte was stable electrochemically up to 5.0 V vs Li/Li + .
IV.* ARYLAMID)~S OF 2-ANILINONICOTINIC ACID AND CYCLIZATION OF THEM TO 4-ARYLAMINO-2,3-B)gNZO-1,8-NAPHTHYRIDINES (1974)

The corresponding arylamides were obtained from methyl 2-anilinonicotinate and dimagnesylamines, and the amides were converted to 4-arylamino-2,3- benzo-l,8-naphth yridines by the action of phosphorus oxychloride. The pK a values of the 2-anilinonicotinic acid arylamides were determined. Substituted 4-amino-2,3-benz o-1,8-naphthyrid ines - analogs of the widely known 9-aminoacridines are of interest as potential physiologically active substances. Such compounds have not been described in the literature. The present research is devoted to the synthesis of 4-arylamino-2,3- benzo-l,8-naphth yridines from 2-anilinonicotinic acid arylamides.
Diastereo- and Regioselectivity in the Reactions of Dilithiated Allylic Secondary Amides with Cyclopent-2-enone (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiastereo- and Regioselectivity in the Reactions of Dilithiated Allylic Secondary Amides with Cyclopent-2-enoneRichard K. Haynes, Scott M. Starling, and Simone C. VonwillerCite this: J. Org. Chem. 1995, 60, 15, 4690–4691Publication Date (Print):July 1, 1995Publication History Published online1 May 2002Published inissue 1 July 1995https://pubs.acs.org/doi/10.1021/jo00120a007https://doi.org/10.1021/jo00120a007research-articleACS PublicationsRequest reuse permissionsArticle Views185Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Hydrogen sensing at room temperature with Pt-coated ZnO thin films and nanorods (2005)

A comparison is made of the sensitivities for detecting hydrogen with Pt-coated single ZnO nanorods and thin films of various thicknesses (20–350 nm). The Pt-coated single nanorods show a current response of approximately a factor of 3 larger at room temperature upon exposure to 500ppmH2 in N2 than the thin films of ZnO. The power consumption with both types of sensors can be very small (in the nW range) when using discontinuous coatings of Pt. Once the Pt coating becomes continuous, the current required to operate the sensors increases to the μW range. The optimum ZnO thin film thickness under our conditions was between 40–170 nm, with the hydrogen sensitivity falling off outside this range. The nanorod sensors show a slower recovery in air after hydrogen exposure than the thin films, but exhibit a faster response to hydrogen, consistent with the notion that the former adsorb relatively more hydrogen on their surface. Both ZnO thin and nanorods cannot detect oxygen.
Continuous-wave dual-wavelength lasing in a two-section vertical-cavity laser (2000)

A vertical-cavity surface-emitting laser with two monolithically grown cavities is presented. The three-terminal device allows current injection into the active regions of both cavities. Under various injection conditions, the device lases continuous wave on either one of the two longitudinal modes supported by the cavity, or on both wavelengths simultaneously. By using a constant injection current in the bottom cavity, and adjusting the current in the top cavity, the device shows all four possible emission states. These are the off states, lasing at the short wavelength /spl lambda//sub S/, at the long wavelength /spl lambda//sub L/, and at both /spl lambda//sub S/ and /spl lambda//sub L/ at the same time.
Review of Value and Lean in Complex Product Development (2015)

ABSTRACT Approaches are being developed to improve complex product development from the perspective of value generation. However, the ideas and their relationships are still not fully articulated. We provide a structured literature review, with a primary but not exclusive focus on value ideas relating to lean in complex system product development. A framework organizes the concepts, methods, and their relationships. It clarifies the value delivery mechanism and could help to understand and thus improve value systems. Areas deserving further research attention are identified.