gebhart/patrepeval huggingface dataset:
Leukocyte apoptosis and its significance in sepsis and shock (2005)

Sepsis and multiple organ failure continue to be significant problems among trauma, burn, and the critically ill patient population. Thus, a number of laboratories have focused on understanding the role of altered apoptotic cell death in contributing to immune and organ dysfunction seen in sepsis and shock. Immune cells that undergo altered apoptotic changes include neutrophils, macrophages, dendritic cells, as well as various lymphocyte populations. Evidence of epithelial as well as endothelial cell apoptotic changes has also been reported. Although mediators such as steroids, tumor necrosis factor, nitric oxide, C5a, and Fas ligand (FasL) appear to contribute to the apoptotic changes, their effects are tissue- and cell population-selective. As inhibiting Fas-FasL signaling (e.g., gene deficiency, Fas fusion protein, or Fas short interfering RNA administration), caspase inhibition (caspase mimetic peptides), and/or the overexpression of downstream antiapoptotic molecules (e.g., Bcl-2, Akt) improve survival of septic mice, it not only demonstrates the pathological significance of this process but points to novel targets for the treatment of sepsis.
Fjx1: A notch‐inducible secreted ligand with specific binding sites in developing mouse embryos and adult brain (2005)

The mouse fjx1 gene was identified as a homologue to the Drosophila gene four-jointed (fj). Fj encodes a transmembrane type II glycoprotein that is partially secreted. The gene was found to be a downstream target of the Notch signaling pathway in leg segmentation and planar cell polarity processes during eye development of Drosophila. Here, we show that fjx1 is not only conserved in vertebrates, but we also identified the murine fjx1 gene as a direct target of Notch signaling. In addition to the previously described expression of fjx1 in mouse brain, we show here that fjx1 is expressed in the peripheral nervous system, epithelial cells of multiple organs, and during limb development. The protein is processed and secreted as a presumptive ligand. Through the use of an fjx1-AP fusion protein, we could visualize fjx1 binding sites at complementary locations, supporting the notion that fjx1 may function as a novel signaling molecule.
Optical coherence tomography for endoscopes, using imaging fibre bundles and a conical mirror (2012)

Imaging fibre bundles and a conical mirror have been used to construct a passive, endoscopic OCT probe with no scanning components at the probe tip. Circular scanning of the beam projected onto the proximal face of the imaging bundle results in a corresponding circular scan at the distal end of the probe. A 45° base-angle conical mirror turns the output light to produce a radially-directed beam that permits circumferential OCT scanning in quasi-cylindrical ducts.
Carbohydrate microarrays: key developments in glycobiology (2009)

Carbohydrate chains of glycoproteins, glycolipids, proteoglycans, and polysaccharides mediate processes of biological and medical importance through their interactions with complementary proteins. The unraveling of these interactions is therefore a priority in biomedical sciences. Carbohydrate microarray technology is a new development at the frontier of glycomics that is revolutionizing the study of carbohydrate-protein interactions and the elucidation of their specificities in endogenous biological processes, microbe-host interactions, and immune defense mechanisms. In this review, we briefly refer to the principles of numerous platforms since the introduction of carbohydrate microarrays in 2002, and we highlight platforms that are beyond proof-of-concept and have provided new biological information.
Quantification of free and esterified steryl glucosides in vegetable oils and biodiesel (2009)

Abstract Steryl glucosides (SG) are minor components that dramatically modify the low temperature performance of fatty acid methyl esters (FAME) used as biodiesel. SG are naturally present in vegetable oils but they may also be the result of the transesterification of esterified steryl glucosides (ESG). These are present in vegetable oils at a level of a few hundred milligrams per kilogram, depending on the nature of the feedstock. We developed an analytical method to quantify SG and ESG in vegetable oils and in FAME. The purification of SG and ESG was performed by liquid chromatography on silica gel, and the analysis of the trimethylsilyl derivatives was achieved by gas chromatography and flame ionization detection. The filterability of biodiesel is affected when the SG content is higher than 20 mg/kg. Therefore, the sensitivity of this new method is adapted for this purpose since the quantification limit is 10 mg/kg of SG and ESG. The recoveries are acceptable, between 75% and 90% depending on the species and content, and the reproducibility relative standard deviation, evaluated at 10%, is comparable to other studies.
Preparation and properties of monodispersed colloidal particles of lanthanide compounds. 2. Cerium(IV) (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and properties of monodispersed colloidal particles of lanthanide compounds. 2. Cerium(IV)Wan Peter Hsu, Lena Ronnquist, and Egon MatijevicCite this: Langmuir 1988, 4, 1, 31–37Publication Date (Print):January 1, 1988Publication History Published online1 May 2002Published inissue 1 January 1988https://pubs.acs.org/doi/10.1021/la00079a005https://doi.org/10.1021/la00079a005research-articleACS PublicationsRequest reuse permissionsArticle Views1502Altmetric-Citations228LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Closing the gap in the capacity of random wireless networks (2004)

We consider the problem of how throughput in a wireless network with randomly located nodes scales as the number of users grows. Following the physical model of Gupta and Kumar, we show that randomly scattered nodes can achieve the optimal 1/(n)/sup 1/2/ per-node transmission rate of arbitrarily located nodes. This contrasts with previous achievable results suggesting that a 1/(n log n)/sup 1/2/ reduced rate is the price to pay for the additional randomness introduced into the system. Our results rely on percolation theory arguments. In the high density regime the network is fully connected but generates excessive interference. In the low density regime the network loses connectivity. Percolation theory ensures that a wireless backbone forms in the transition region between this two extreme scalings. This backbone does not cover all the nodes, nevertheless it is sufficiently rich in crossing paths so that it can transport all the traffic in the network. By operating the network in this transition region between order and disorder, we are able to prove our tight bound.
Biomechanical Assessment of Compression Screws (1998)

A series of mechanical tests on anatomic specimen cancellous bone and cancellous bonelike foam were conducted to evaluate and compare an Acutrak compression screw with an AO 4-mm cancellous screw and the Herbert screw. The Acutrak and AO screws produced similar fragment compression in foam and bone; Acutrak and AO compression were significantly greater than that of the Herbert screw. However, Acutrak was able to maintain compression after cyclic loading significantly better than were the AO and Herbert screws. The pushout force of Acutrak and AO screws were significantly greater than that of the Herbert screw in foam and bone. The torque required to break fragment contact was significantly greater for the Acutrak than for the AO or Herbert screws, but that for the AO was greater than that for the Herbert screw. The results of this analysis show the Acutrak screw is capable of producing and maintaining compression between bone fracture fragments. In addition, the Acutrak screw was shown to have superior mechanical characteristics than did Herbert screw in every mode tested. The Acutrak screw did not surpass the fragment compression achieved by the AO screw in foam, but it did not overtighten or experience degradation of compression after 500 cycles of simulated physiologic loading.
Case 31-1985 (1985)

CASE 31–1985Presentation of CaseA 43-year-old man was referred to the hospital because of fever of unknown origin.There was a history of coarctation of the aorta, with surgical repair at the age of 12 years; an appendectomy was performed two years later. Thereafter he was well until 10 years before admission, when he had a urinary tract infection, from which he recovered. Approximately one year later he began to experience repeated bouts of fever that occurred at infrequent intervals, sometimes associated with a sore throat and upper respiratory tract symptoms. During the episodes of fever the patient experienced . . .
Campylobacter pyloridis and Gastritis: Association with Intercellular Spaces and Adaptation to an Environment of Mucus as Important Factors in Colonization of the Gastric Epithelium (1986)

Stomach biopsy specimens from greater than 40 individuals with Campylobacter pyloridis-associated gastritis were examined by light and electron microscopy. The bacteria were consistently seen in two locations: within the gastric mucus and associated with intercellular junctions of gastric epithelial cells. C. pyloridis is suggested to be one of a broad group of spiral bacteria that are adapted to the peculiar niche provided by intestinal mucus. The spiral morphology and the form of motility of these organisms give them a selective advantage in a viscous environment. This point has been demonstrated in vitro by measurement of the velocity of clinical isolates in solutions of methyl cellulose of varying viscosity. The localization of C. pyloridis close to intercellular junctions is proposed to be due to the presence of preferred metabolites or growth factors, e.g., urea and hemin. All isolates show an extremely high urease activity and require hemin for growth.
MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma (2011)

miRNA expression profiles for resected PDAC were examined to identify potentially prognostic miRNAs. miRNA microarray analysis identified statistically unique profiles, which could discriminate PDAC from paired nonmalignant pancreatic tissues as well as molecular signatures that differ according to pathologic features. miRNA expression profiles correlated with overall survival of PDAC following resection, indicating that miRNAs provide prognostic utility.
Quadrature Multiplexed RF Excitation in NMR Imaging - Application to Slice by Slice and Chunk 3-D Techniques (1986)

Simultaneous RF pulse excitation with a quadrature multiplexing technique has been proposed to double the magnetic resonance signal information in a given imaging time. This method uses two selective RF pulses with 90/sup 0/ phase difference to excite two slice spins to real and imaginary domains. With a proper phase correction, this scheme doubles the number of slices or the imaging region in a given data acquisition time as the conventional case. An implementation of this technique to slice by slice and chunk 3-D imaging methods is done for human head using the 1.5 T superconducting magnet imaging system.
Application of differential display to identify genes for lung cancer detection in peripheral blood (2002)

A blood assay for detection of lung cancer biomarkers could significantly improve cancer patient prognosis and survival rates. Amplified fragment length polymorphism-differential display (AFLP-DD) was used to identify gene transcripts found in lung cancer tissue and the peripheral blood of lung cancer patients. The clones were evaluated for gene expression in lung cancer tissue, peripheral blood of lung cancer patients and healthy volunteers' blood. The isolated gene transcript clones were found to be from the syndecan 1 gene, collagen 1 gene and 2 novel genes. All 4 transcripts were expressed in normal lung tissue, 4 cultured primary lung cells and 6 lung cancer cell lines. RNA was isolated from peripheral blood samples of 69 lung cancer patients. Reverse transcriptase polymerase chain reaction (RT-PCR) was used to test for the presence of cytokeratin 19 and the 4 gene mRNA transcripts in blood RNA. The positive detection rate of at least 1 of the 5 transcripts was 79% for lung adenocarcinoma and 62% for squamous carcinoma. Using RT-PCR, at least 1 of the markers was found in 53% of stage I patients, 100% of stage II, 71% of stage III and 81% of stage IV lung cancer patients. Blood samples from 20 healthy volunteers were also tested, but only 1 of the 5 transcripts was found in 1 patient. These new molecular markers may aid early detection, staging and follow-up of lung cancer patients by RNA isolated from blood.
Research of the Evaluation System of Management Staff Training (2009)

The City Company of Power Supply launched a lot of training for the middle and lower management staff.In order to evaluate the result of these training,a practical evaluation system should be constructed.This article explained the background,the content,the characteristics and the effect of the evaluation system,and proved that this evaluation system had meaningful function and popularized value for the extension and the promotion of the management staff training.
Identification and Characterization of Two Novel Clostridial Bacteriocins, Circularin A and Closticin 574 (2003)

Two novel antibacterial peptides of clostridial species were purified, N-terminally sequenced, and characterized. Moreover, their structural genes were identified. Closticin 574 is an 82-amino-acid bacteriocin produced by Clostridium tyrobutyricum ADRIAT 932. The supernatant of the producing strain showed a high level of activity against the indicator strain C. tyrobutyricum. The protein is synthesized as a preproprotein that is possibly secreted via the general secretion pathway, after which it is hydrolyzed at an Asp-Pro site. Circularin A is produced by Clostridium beijerinckii ATCC 25752 as a prepeptide of 72 amino acids. Cleavage of the prepeptide between the third leucine and fourth valine residues followed by a head-to-tail ligation between the N and C termini creates a circular antimicrobial peptide of 69 amino acids. The unusually small circularin A leader peptide of three amino acids is cleaved off in this process. The supernatant of C. beijerinckii ATCC 25752 showed a broad antibacterial activity range.
Selective Anodic Oxidation of 5-Hydroxymethylfurfural (1996)

A selective electrochemical oxidation of 5-hydroxymethylfurfural to 2,5-furandicarbaldehyde was performed. Yields were various depending on the time of the reaction and on the kind of salt used as a supporting electrolyte.
SEFOP: a novel approach to data path module placement (1993)

This paper is concerned with utilizing regularity information of data path modules in placement and shows outstanding results. Similarity Extraction is applied first on a data path module given a set of slice numbers, a column number, and IO pin ordering followed by a three-level Force-Oriented Placement for determining relative locations of cells in the form of a cell matrix. exact pin locations, cell flipping, and row/column spacing are then estimated based on the cell placement. Experiments on cell-based designs demonstrate its performance over various generate-purpose approaches at far less CPU time on data path module designs.
Efficient Virtual Machine Placement for On-Demand Access to Infrastructure Resourcesin Cloud Computing (2013)

Cloud computing is the utility computing that provides virtualized resources, applications, and services using distributed network and Internet. Cloud computing service offers the ability to scale up and scale down your computing requirements and most importantly to reduce the cost of deployment. Many organizations are migrating to cloud computing services to lower the risk and for better business continuity.In case of on-demand access user requests infrastructure services for immediate access and for a very short interval of time, they have to pay certain charge depending upon that duration.In cloud computing, infrastructure requests are served by the allocation of virtual machines to those requests; these virtual machines should be placed on the underlying hardware infrastructure called datacenter. In this paper we have proposed a model for the efficient allocation of virtual machines on the cloud infrastructure to reduce the allocation time and to optimize the resource utilization. The proposed model is simulated and its performance is compared with two other existing models.
The Anisotropic Noise in Stochastic Gradient Descent: Its Behavior of Escaping from Sharp Minima and Regularization Effects (2018)

Understanding the behavior of stochastic gradient descent (SGD) in the context of deep neural networks has raised lots of concerns recently. Along this line, we study a general form of gradient based optimization dynamics with unbiased noise, which unifies SGD and standard Langevin dynamics. Through investigating this general optimization dynamics, we analyze the behavior of SGD on escaping from minima and its regularization effects. A novel indicator is derived to characterize the efficiency of escaping from minima through measuring the alignment of noise covariance and the curvature of loss function. Based on this indicator, two conditions are established to show which type of noise structure is superior to isotropic noise in term of escaping efficiency. We further show that the anisotropic noise in SGD satisfies the two conditions, and thus helps to escape from sharp and poor minima effectively, towards more stable and flat minima that typically generalize well. We systematically design various experiments to verify the benefits of the anisotropic noise, compared with full gradient descent plus isotropic diffusion (i.e. Langevin dynamics).
Axial-flow microturbine with electromagnetic generator: design, CFD simulation, and prototype demonstration (2004)

We have developed a MEMS power conversion device that combines an axial-flow turbine with an axial-flux electromagnetic generator. This device can generate electrical power when placed in an air-stream, and is aimed at applications such as flow sensing and power generation for remote sensors. Recent experimental performance data are presented for prototypes, and compared with CFD (computational fluid dynamics) simulations. The current devices have a volume of approximately 0.5 cm/sup 3/, generate 1 mW of output power at a pressure drop of 8 mbar and a flow rate of 35 litres per minute, and will operate at pressure drops down to a few mbar.
Las artritis sépticas agudas en el niño (1976)

espanolSe estudia el problema de las artritis septicas en el lactante y primera infancia basandose en la revision de 12 casos. Se insiste sobre la importancia y dificultad de un diagnostico precoz, sobre todo a nivel de la cadera. Se senala el mal pronostico de las coxitis en relacion con las otras localizaciones articulares. Se revisa el tratamiento precoz, asi como el de sus secuelas, frecuentes estas a nivel de las caderas si no se hace un diagnostico y tratamiento precoz. Se presenta el buen resultado obtenido en un caso mediante la operacion de Weissman como metodo estabilizador de la cadera. English12 cases of septic arthritis in infancy and childhood have been revised. The importance and difficulty of early diagnosis, mainty at the hip, has been stressed. Septic arthritis of the hip joint has a bad prognosis. A study of the early treatment of the hip disease, as well as the management of its secuelae has been made. The good result of the a case treated by means of the Weissman operation, as a stabilizing procedure, has been pointed out.
Sequential Hydrolysis of Three Acyl Ester Bonds in TrioleinMolecule by Human Gastric Juice Lipase (1983)

Specificity of gastric juice lipase concerning the sequential hydrolysis of three acyl ester bonds of triolein molecule has been compared with that of pancreatic lipase. The rates of the individual hydrolytic steps were calculated by applying the method based on the amounts of chromatographically separated hydrolysis products present upon the incubation of tritium-labelled triolein with a lipolytic enzyme. It was found that in the case of gastric lipase the rates of all three steps of triolein hydrolysis are similar, whereas in the case of pancreatic lipase the last step proceeds at a much slower rate than the preceding ones.
Incorporation of Gallium into Zeolites:  Syntheses, Properties and Catalytic Application (2000)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIncorporation of Gallium into Zeolites: Syntheses, Properties and Catalytic ApplicationRolf Fricke, Hendrik Kosslick, Günter Lischke, and Manfred RichterView Author Information Institute of Applied Chemistry, Richard-Willstätter-Str. 12, D-12489 Berlin, Germany and Technische Fachhochschule Wildau, Bahnhofstrasse, D-15745 Wildau, Germany Cite this: Chem. Rev. 2000, 100, 6, 2303–2406Publication Date (Web):May 24, 2000Publication History Received18 May 1999Published online24 May 2000Published inissue 1 June 2000https://pubs.acs.org/doi/10.1021/cr9411637https://doi.org/10.1021/cr9411637research-articleACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views7025Altmetric-Citations346LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Catalysts,Chemical structure,Gallium,Ions,Zeolites Get e-Alerts
Telemetry system for heart-rate and blood temperature using a microcomputer (1985)

A radio-telemetry system using a microcomputer has been constructed to measure both the heart-rate (HR) and right atrial blood-temperature in dogs. The telemeter incorporates a thermistor temperature probe, which allows blood-temperature measurements in the range of 35 degrees-42 degrees C with an available resolution of +/- 0.02 degree C. The output of the receiver is connected to active filters, a frequency counter and an HR meter, and finally to a microcomputer, through an appropriate interface circuit, for data linearization and storage.