gebhart/patrepeval huggingface dataset:
The Predictive Value of Ultrasonography in Evaluation of Infants with Posterior Urethral Valves (1992)

Between 1981 and 1989, 28 infants less than 6 months old with posterior urethral valves underwent ultrasound evaluation as part of the initial evaluation at our hospital. The single ultrasound feature that correlated with subsequent renal function was the status of corticomedullary differentiation. The presence of corticomedullary junctions in at least 1 kidney in 17 infants was always associated with a serum creatinine level of 0.8 mg./dl. or less in long-term followup. Of 11 patients with absent corticomedullary differentiation 7 had eventual creatinine levels of greater than 0.8 mg./dl. with 5 of them suffering clinically significant renal insufficiency. An association between vesicoureteral reflux and absent corticomedullary junctions was also found.
Automated Surface Wave Method: Field Testing (1993)

The spectral analysis of surface waves (SASW) method is a nondestructive in situ seismic testing method for determining shear wave velocity profiles of soil sites and stiffness profiles of pavement systems. The key steps involved are construction of an experimental dispersion curve from data collected in situ, and inversion of the dispersion curve to determine the stiffness profile. In this paper, an automated method for the construction of dispersion curves is discussed. Weighted least‐squares best‐fit solution is used to estimate the phase at each frequency with coherence as weighing function. By knowing the distance between the receivers and the phase at each frequency, phase velocity and wavelength associated with that frequency are calculated. These raw data are then combined using the least‐absolute‐valuebest‐fit criterion to construct a dispersion curve. The inversion process for determination of stiffness profile from the dispersion curve is described in a companion paper.
The ABCs of the Internet (1996)

The ABCs of the Internet , The ABCs of the Internet , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Randomized Clinical Trial on the Use of PHYSTA Freeze-Dried Water Extract of<i>Eurycoma longifolia</i>for the Improvement of Quality of Life and Sexual Well-Being in Men (2012)

Eurycoma longifolia is reputed as an aphrodisiac and remedy for decreased male libido. A randomized, double-blind, placebo controlled, parallel group study was carried out to investigate the clinical evidence of E. longifolia in men. The 12-week study in 109 men between 30 and 55 years of age consisted of either treatment of 300 mg of water extract of E. longifolia (Physta) or placebo. Primary endpoints were the Quality of Life investigated by SF-36 questionnaire and Sexual Well-Being investigated by International Index of Erectile Function (IIEF) and Sexual Health Questionnaires (SHQ); Seminal Fluid Analysis (SFA), fat mass and safety profiles. Repeated measures ANOVA analysis was used to compare changes in the endpoints. The E. longifolia (EL) group significantly improved in the domain Physical Functioning of SF-36, from baseline to week 12 compared to placebo (P = 0.006) and in between group at week 12 (P = 0.028). The EL group showed higher scores in the overall Erectile Function domain in IIEF (P < 0.001), sexual libido (14% by week 12), SFA- with sperm motility at 44.4%, and semen volume at 18.2% at the end of treatment. Subjects with BMI ≥ 25 kg/m(2) significantly improved in fat mass lost (P = 0.008). All safety parameters were comparable to placebo.
A radioimmunoassay for erythropoietin: serum levels in normal human subjects and patients with hemopoietic disorders. (1982)

An RIA for Ep has been developed that is highly sensitive and specific. A homogeneous Ep preparation was labeled with 125 I by the chloramine-T method to a specific activity of 90 to 136 micro Ci/microgram and immunoreactivity of 80%. Ep antiserum, which was produced to a human urinary Ep preparation (80 U/mg of protein), was adsorbed with normal human urinary and serum proteins without any loss in sensitivity of the RIA to increase the specificity of the assay. A good correlation was seen between the RIA and the exhypoxic polycythemic mouse assay (corr. coef. 0.967; slope 1.05 and "y" intercept 0.75). Ep titers in sera from 175 hematologically normal human subjects exhibited a normal frequency distribution and ranged between 5.8 and 36.6 mU/ml with a mean of 14.9 +/- 4.7 (S.D.) and median of 14.3 Serum Ep titers were markedly elevated in seven patients with aplastic anemia and one patient with pure red cell aplasia (1350 to 20,640 mU/ml) and were lower than normal in two patients with polycythemia vera (8.1 and 9.4 mU/ml). The serum Ep titers in a prenephrectomy patient with chronic glomerulonephritis (32.1 mU/ml) decreased to below normal levels (9.04 mU/ml) after nephrectomy. The cord serum erythropoietin titers in 10 IDM [90.82 +/- 134.1 (S.D.) mu/ml] returned to values within the normal range (13.86 +/- 5.55) on day 3 after birth, suggesting the utility of the RIA in elucidating the role of hypoxia and/or insulin in increased erythropoiesis in IDM. The serum Ep titers in patients with anemias and polycythemias were compared to those of normal human subjects and agreed well with pathophysiologic mechanisms of these hemopoietic disorders, confirming the validity of the RIA.
High-resolution observation by double-biprism electron holography (2004)

High-resolution electron holography has been achieved by using a double-biprism interferometer implemented on a 1MV field emission electron microscope. The interferometer was installed behind the first magnifying lens to narrow carrier fringes and thus enabled complete separation of sideband Fourier spectrum from center band in reconstruction process. Holograms of Au fine particles and single-crystalline thin films with the finest fringe spacing of 4.2pm were recorded and reconstructed. The overall holography system including the reconstruction process performed well for holograms in which carrier fringes had a spacing of around 10pm. High-resolution lattice images of the amplitude and phase were clearly reconstructed without mixing of the center band and sideband information. Additionally, entire holograms were recorded without Fresnel fringes normally generated by the filament electrode of the biprism, and the holograms were thus reconstructed without the artifacts caused by Fresnel fringes.
<sup>1</sup>H,<sup>13</sup>C,<sup>15</sup>N, 2D and variable temperature NMR study of the role of hydrogen bonding in the structure and conformation of oxamide derivatives (1993)

The structure and conformation of N,N′-bis[(2-hydroxy)phenyl]oxamide (1); N,N′-bis[(2-methoxy)-phenyl]oxamide (2); N,N′-bis(phenyl)oxamide (3); N,N′-bis[(1R,2S)-(–)-norephedrine]oxamide (4); N,N′-bis[(1R,2R)-(–)-norpseudoephedrine]oxamide (5); N-[(2-hydroxy)phenyl]methylamide (6); N-[(2-methoxy)phenyl]methylamide (7); N-phenylmethylamide (8); N-[(–)-norephedrine]-methylamide (9) and N-[(–)-norpseudoephedrine]methylamide (10) were unambiguously established by 1H, 13C, 15N, 2D and variable temperature NMR spectroscopy. A careful NMR investigation of the conformational behaviour in these systems was relevant. It has been found that the dicarbonylic group in compounds 1–5 has a trans geometry, stabilized by intramolecular hydrogen bonding and that they possess a C2 axis. Compounds 1 and 2 are planar and compounds 1, 2, 4 and 5 present the amidic proton coordinated by two oxygen atoms.
Case Detection, Diagnosis, and Treatment of Patients with Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline (2008)

We recommend case detection of primary aldosteronism be sought in higher risk groups of hypertensive patients and those with hypokalemia by determining the aldosterone-renin ratio under standard conditions and that the condition be confirmed/excluded by one of four commonly used confirmatory tests. We recommend that all patients with primary aldosteronism undergo adrenal computed tomography as the initial study in subtype testing and to exclude adrenocortical carcinoma. We recommend the presence of a unilateral form of primary aldosteronism should be established/excluded by bilateral adrenal venous sampling by an experienced radiologist and, where present, optimally treated by laparoscopic adrenalectomy. We recommend that patients with bilateral adrenal hyperplasia, or those unsuitable for surgery, optimally be treated medically by mineralocorticoid receptor antagonists.
Deterministic Construction of Compressed Sensing Matrices via Algebraic Curves (2012)

Compressed sensing is a sampling technique which provides a fundamentally new approach to data acquisition. Comparing with traditional methods, compressed sensing makes full use of sparsity so that a sparse signal can be reconstructed from very few measurements. A central problem in compressed sensing is the construction of sensing matrices. While random sensing matrices have been studied intensively, only a few deterministic constructions are known. Inspired by algebraic geometry codes, we introduce a new deterministic construction via algebraic curves over finite fields, which is a natural generalization of DeVore's construction using polynomials over finite fields. The diversity of algebraic curves provides numerous choices for sensing matrices. By choosing appropriate curves, we are able to construct binary sensing matrices which are superior to Devore's ones. We hope this connection between algebraic geometry and compressed sensing will provide a new point of view and stimulate further research in both areas.
Side effects of a dopamine agonist therapy for Parkinson's disease: a mini-review of clinical pharmacology. (2016)

Dopamine agonists (DA) are therapeutic agents that are commonly used in the treatment of Parkinson's disease (PD). They can reduce undesired motor fluctuations and delay the administration of levodopa therapy. However, this drug family is associated with specific side effects that can significantly diminish the quality of life among PD patients. Some of them impose significant risks for individuals who have a history of cardiovascular diseases, psychosis, and depression, or those older patients who suffer from renal or hepatic insufficiency. Various pharmacokinetic and pharmacodynamic considerations need to be taken into account when administering DA therapy. The goal of this review is to provide a comprehensive, up-to-date overview of DA therapeutic modalities for PD.
Acute-phase, indirect fluorescent antibody procedure for diagnosis of Mycoplasma pneumoniae infection. (1983)

An indirect fluorescent antibody (IFA) technique was developed to detect IgG and IgM-specific antibodies to Mycoplasma pneumoniae. The presence of IgM-specific mycoplasma antibody was interpreted as reflecting active infection in patients with atypical pneumonia or other clinically compatible illness. The procedure is suitable for use in routine clinical laboratories, correlated well with complement fixation test results and did not show cross reaction with Legionella pneumophila antibody. The ready availability of an acute-phase procedure for diagnosis of Mycoplasma pneumoniae infection permits therapeutic judgments based on testing of the acute serum sample.
Age-Related Changes in the Function of the Pituitary-Gonadal Axis in a Sterile Male Rat Mutant (hd/hd)1 (1991)

Testicular growth is depressed in the genetically sterile male rat (hd/hd) relative to its LE phenotype littermates (by 50% and 73% at 27 and 90 days of age, respectively). Within the hd/hd testis, both the tubular and seminiferous tubule tissues are affected by the mutation. In addition, there is significantly less germ cell production from the primary spermatocyte stage of spermatogenesis onwards and the total number of Sertoli cells observed is less. In the intertubular tissue, the total volume and the total number of Leydig cells per testis is significantly less, but the mean volume of an average Leydig cell is not modified. The serum gonadotropin levels are higher in the hd/hd rat, whereas from 40 days of age onwards the level of testosterone is lower. The FSH and LH binding affinity constants are unchanged by the mutation; however, the total number of FSH binding sites per 10(6) Sertoli cells is lower while that of LH per 10(6) Leydig cells is greater. Indeed, it is likely that the lesser concentration of serum testosterone in the hd/hd rat is a result of a smaller number of Leydig cells since their individual function is not modified. The testicular androgen binding protein (ABP) content and the ABP output towards the epididymis are lower as a consequence of both a lesser number and an altered function of the Sertoli cells.(ABSTRACT TRUNCATED AT 250 WORDS)
Vibrational characterization of E102 food additive by Raman and surface‐enhanced Raman spectroscopy and theoretical studies (2005)

Abstract The well‐known food dye E102 could be detected in aqueous solutions by means of regular Raman and surface‐enhanced Raman scattering (SERS) spectroscopy at micromolar and nanomolar levels, respectively. The changes observed in the profile of the band at 1365 cm −1 , characteristic of the ν(NN) mode of the azo chromophore group, allowed us to establish the present species in the Raman and SERS solutions at different concentrations or pH values. Protonation at the azo group of the molecule was detected for acidic pH values <3. In the pH range 3–8, no changes in the molecular species were observed. Density functional theory (DFT)‐calculated geometries, harmonic vibrational modes and Raman scattering activities for E102 were in good agreement with the experimental data, a complete vibrational assignment being proposed. A strong chemical interaction of E102 with colloidal particles was evidenced and an adsorbed geometry was proposed. Copyright © 2005 John Wiley & Sons, Ltd.
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. (1991)

We have used immunofluorescence staining to study the subcellular distribution of cyclin A and B1 during the somatic cell cycle. In both primary human fibroblasts and in epithelial tumor cells, we find that cyclin A is predominantly nuclear from S phase onwards. Cyclin A may associated with condensing chromosomes in prophase, but is not associated with condensed chromosomes in metaphase. By contrast, cyclin B1 accumulates in the cytoplasm of interphase cells and only enters the nucleus at the beginning of mitosis, before nuclear lamina breakdown. In mitotic cells, cyclin B1 associates with condensed chromosomes in prophase and metaphase, and with the mitotic apparatus. Cyclin A is degraded during metaphase and cyclin B1 is precipitously destroyed at the metaphase----anaphase transition. Cell fractionation and immunoprecipitation studies showed that both cyclin A and cyclin B1 are associated with PSTAIRE-containing proteins. The nuclear, but not the cytoplasmic form, of cyclin A is associated with a 33-kD PSTAIRE-containing protein. Cyclin B1 is associated with p34cdc2 in the cytoplasm. Thus we propose that the different localization of cyclin A and cyclin B1 in the cell cycle could be the means by which the two types of mitotic cyclin confer substrate specificity upon their associated PSTAIRE-containing protein kinase subunit.
Synthesis of Amorphous Monomeric Glass Mixtures for Organic Electronic Applications (2015)

We report a divergent synthetic strategy and novel design concept that exploit molecular mixtures to create amorphous organic charge-transporting glasses. Using Suzuki-Miyaura cross-coupling reactions, we synthesized well-defined molecular mixtures in a single step. These solution-processable materials are noncrystalline and show good thermal and morphological stabilities. Moreover, they have robust hole and electron mobilities, which make them excellent candidate materials for organic light-emitting diodes. Our general strategy enables the facile synthesis of noncrystalline materials with well-controlled electronic properties.
Enhancing the Speed of SiGe HBTs Using fT-Doubler Techniques (2008)

A peak f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> of 325 GHz is achieved, for the first time, in a 130 nm, 200 GHz, 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -generation SiGe HBT technology at 300 K, by utilizing f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> -doubler techniques. This speed enhancement is equivalent to gaining an additional generational node (from 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> to 4 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> ), with no underlying change to the transistor profile or lithography. The f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> -doubler can be treated as a single transistor unit cell during circuit design, which is verified by the investigation of its small-signal equivalent circuit. Reduced C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">pi</sub> is demonstrated to be the root origin of the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> -enhancement. The impact of emitter geometry on performance is investigated. A record f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> of 438 GHz is achieved at 93 K.
Both species of chlamydia and two biovars of <i>Chlamydia trachomatis</i> stimulate mouse B lymphocytes. (1986)

We have investigated the ability of both species of chlamydiae (C. trachomatis and C. psittaci), two major biovars of C. trachomatis (lymphogranuloma venereum and trachoma), and the two developmental forms of chlamydia (reticulate and elementary bodies) to stimulate murine spleen lymphocytes. All of these forms of the bacteria induce potent proliferation and differentiation to plaque-forming cells by B lymphocytes in vitro. Chlamydiae induce a broad antibody response, suggesting that stimulation is polyclonal in nature. Although all chlamydiae possess a lipopolysaccharide (LPS) genus-specific molecule similar to LPS found on Re mutant enterobacteria, polyclonal B cell stimulation is likely caused by molecules other than LPS, since i) polymyxin B failed to inhibit chlamydia-induced immunostimulation and ii) C3H/HeJ mice (LPS nonresponders) produced normal numbers of PFC after culture with chlamydia (but not LPS). Thus, a cross-species moiety that is not LPS is responsible for polyclonal stimulation by chlamydia. Because these bacteria can exist in latent forms in an animal, and all forms are immunostimulatory, the question of whether these bacteria can alter immune responses if released during other infections or immunizations has been raised.
Life-supporting pig-to-baboon heart xenotransplantation. (1998)

Hyperacute rejection is abrogated in pig-to-baboon heart xenotransplantation with the expression of the human decay-accelerating factor transgene. The human decay-accelerating factor transgenic pig heart is able to support primate life for a prolonged period.
[Physiologic validation of the method of functional hearing tests for evaluation of hearing function]. (1994)

Physiological validation is presented for application of ototopicometry. This method is intended for measurements of minimal recognizable angles of a moving sound object localization in several space planes. Quantitative characteristics of ototopical function in healthy subjects upon localization of various sound stimuli are described. Ototopicometry is proposed as an additional audiological test for functional assessment of the acoustic human system.
Biosynthesis of Secoiridoid Glucosides (1976)

In the present review the biosynthetic pathways of sweroside, morroniside and oleuropein type secoiridoid glucosides through mevalonic acid (MVA), geraniol, deoxyloganin, loganin etc. are outlined.The biosynthesis of alkaloidal glucosides, which can be regarded as kinds of secoiridoids, is also briefly described.
Synthesis, Crystal Structure, and Magnetic Properties of a Three-Dimensional Cyano-Bridged Bimetallic Coordination Polymer with an Aromatic Amine Capping Ligand:  [Cu(2,2‘-dpa)]<sub>3</sub>[Cr(CN)<sub>6</sub>]<sub>2</sub>·3H<sub>2</sub>O (2,2‘-dpa = 2,2‘-Dipicolylamine) (2005)

A three-dimensional (3D) Cu(II)-containing Prussian Blue analogue with two types of [Cr(CN)6]3- units, [Cu(2,2‘-dpa)]3[Cr(CN)6]2·3H2O (2,2‘-dpa = 2,2‘-dipicolylamine), was synthesized and characterized. One type of [Cr(CN)6]3- unit in this complex coordinates to six copper(II) atoms to form the heptanuclear [CrCu6] unit, which connects with other [CrCu6] units through the other type of [Cr(CN)6]3- unit acting as bidentate spacer link only. Magnetic investigations of this complex revealed that long-range ferromagnetic ordering occurs below the Curie temperature of 3 K. It is the first example of 3D complex-based Prussian Blue analogues containing aromatic amine capping ligands.
Wohnungsmarkt und Wohnungsversorgung (1997)

Es ist heutzutage unstrittig, daß Nachfrager und Anbieter durch den freien Kauf bzw. Verkauf von Gütern auf Märkten beidseitige Vorteile erzielen und dem Marktpreis die Funktion zukommt, Knappheit zu signalisieren sowie Angebot und Nachfrage aufeinander abzustimmen. Kommt man aber auf den Wohnungsmarkt zu sprechen, so bricht dieser Konsens auseinander. Allenthalben wird beklagt, daß gemessen am „Wohnungsbedarf“ die Wohnungsversorgung unzureichend sei, die Mietbelastungen zu hoch wären und dies seine Ursache in Funktionsmängeln des Wohnungsmarktes habe. So wird z.B konstatiert, auf einem freien Wohnungsmarkt herrsche „in der Regel ein Bedarfs- und Nachfrageüberhang, der den Wohnungsanbietern Marktvorteile verschaffe“ und gefolgert, „daß die Selbststeuerungskräfte des Wohnungsmarktes in der (alten) Bundesrepublik vor der öffentlichen Aufgabe versagen, preisgünstigen Wohnraum in ausreichender Zahl bereitzustellen bzw. zu erhalten“ (Holtmann/Killisch 1993:3, Hervorhebung im Original).1 Daran schließt sich zumeist die Forderung nach staatlichen Eingriffen an, die diese Mängel kompensieren sollen. Dabei gerät häufig in Vergessenheit, daß der Wohnungsmarkt schon seit langem eine so hohe Regulierungsdichte aufweist, wie sie wohl kaum auf anderen wichtigen Gütermärkten in Deutschland zu finden ist. Dies betrifft sowohl direkte staatliche Eingriffe in die Preis- bzw. Mengenbildung auf dem Wohnungsmarkt sowie Reglementierungen des Vertrags- und Nutzungsrechtes als auch indirekte Maßnahmen, wie z.B. Subventionen. Im Nachhinein muß es deshalb schwerfallen, Fehlentwicklungen am Wohnungsmarkt eindeutig einem „Marktversagen“ oder einem „Staatsversagen“ zuzuordnen.
Concept and Enabling Technologies of Spectrum-Sliced Elastic Optical Path Network (SLICE) (2009)

A novel, spectrum-efficient and scalable optical transport network architecture called spectrum-sliced “elastic optical path” network (SLICE) is presented. The SLICE architecture enables sub-wavelength, super-wavelength, multiple-rate data traffic accommodation, and elastic variation of allocated resources in a highly spectrum-efficient manner.