gebhart/patrepeval huggingface dataset:
Demonstration of Borrelia burgdorferi DNA in urine samples from healthy humans whose sera contain B. burgdorferi-specific antibodies (1994)

Since the possibility of asymptomatic infection with Borrelia burgdorferi has been suggested by a positive serology found in healthy subjects, we hypothesized that these subjects might excrete borrelial DNA sequences in urine as happens in patients with Lyme borreliosis. We found borrelial sequences by nested PCR in the urine samples from 3 of 13 healthy B. burgdorferi antibody-positive adults but not in urine samples from 79 antibody-negative healthy controls. After therapy with doxycycline, the urine samples were repeatedly negative for B. burgdorferi DNA. We conclude that urinary excretion of borrelial DNA sequences may occur in seropositive healthy subjects during asymptomatic infection. Demonstration of such sequences in urine must be interpreted cautiously and may not necessarily prove a borrelial cause of disease.
Model predictive filtering for improved temporal resolution in MRI temperature imaging (2010)

A novel method for reconstructing MRI temperature maps from undersampled data is presented. The method, model predictive filtering, combines temperature predictions from a preidentified thermal model with undersampled k-space data to create temperature maps in near real time. The model predictive filtering algorithm was implemented in three ways: using retrospectively undersampled k-space data from a fully sampled two-dimensional gradient echo (GRE) sequence (reduction factors R = 2.7 to R = 7.1), using actually undersampled data from a two-dimensional GRE sequence (R = 4.8), and using actually undersampled data from a three-dimensional GRE sequence (R = 12.1). Thirty-nine high-intensity focused ultrasound heating experiments were performed under MRI monitoring to test the model predictive filtering technique against the current gold standard for MR temperature mapping, the proton resonance frequency shift method. For both of the two-dimensional implementations, the average error over the five hottest voxels from the hottest time frame remained between +/-0.8 degrees C and the temperature root mean square error over a 24 x 7 x 3 x 25-voxel region of interest remained below 0.35 degrees C. The largest errors for the three-dimensional implementation were slightly worse: -1.4 degrees C for the mean error of the five hottest voxels and 0.61 degrees C for the temperature root mean square error.
Regulation of the dauBAR operon and characterization of d-amino acid dehydrogenase DauA in arginine and lysine catabolism of Pseudomonas aeruginosa PAO1 (2009)

A unique D-to-L racemization of arginine by coupled arginine dehydrogenases DauA and DauB encoded by the dauBAR operon has been recently reported as a prerequisite for D-arginine utilization as the sole source of carbon and nitrogen through L-arginine catabolic pathways in P. aeruginosa. In this study, enzymic properties of the catabolic FAD-dependent d-amino acid dehydrogenase DauA and the physiological functions of the dauBAR operon were further characterized with other d-amino acids. These results establish DauA as a D-amino acid dehydrogenase of broad substrate specificity, with D-Arg and D-Lys as the two most effective substrates, based on the kinetic parameters. In addition, expression of dauBAR is specifically induced by exogenous D-Arg and D-Lys, and mutations in the dauBAR operon affect utilization of these two amino acids alone. The function of DauR as a repressor in the control of the dauBAR operon was demonstrated by dauB promoter activity measurements in vivo and mobility shift assays with purified His-tagged protein in vitro. The potential effect of 2-ketoarginine (2-KA) derived from D-Arg deamination by DauA as a signal molecule in dauBAR induction was first revealed by mutation analysis and further supported by its in vitro effect on alleviation of DauR-DNA interactions. Through sequence analysis, putative DauR operators were identified and confirmed by mutation analysis. Induction of the dauBAR operon to the maximal level was found to require the L-arginine-responsive regulator ArgR, as supported by the loss of inductive effect by L-Arg on dauBAR expression in the argR mutant and binding of purified ArgR to the dauB regulatory region in vitro. In summary, this study establishes that optimal induction of the dauBAR operon requires relief of DauR repression by 2-KA and activation of ArgR by L-Arg as a result of d-Arg racemization by the encoded DauA and DauB.
Elektrisches und optisches Verhalten von Halbleitern. X Elektrische Messungen an Zinkoxyd (1935)

Abstract An zahlreichen Einkristallen, Kristalliten und an aufgedampften Schichten aus Zinkoxyd , deren Herstellung ausführlich beschrieben wird, wurden Leitfähigkeitsmessungen im Temperaturbereich zwischen Zimmertemperatur und flüssiger Luft, ferner Halleffekts‐ und Thermospannungsmessungen ausgeführt. Insbesondere wurden die Einflüsse einer Glühbehandlung in Sauerstoff bzw. im Vakuum auf die elektrische Leitfähigkeit untersucht. Durchsichtige, homogene Schichten von metallischem Zink lassen sich durch Verdampfung von Zinkoxyd im Vakuum erhalten. Außerhalb des Rahmens dieser Arbeit wurde für Kupferoxydul ein positives Hallspannungsvorzeichen ‐ entgegen früheren Literaturangaben ‐ gefunden.
<title>Lifetime-based sensing in highly scattering media</title> (1995)

Fluorescence lifetime-based sensing is now recognized as a valuable methodology in clinical and analytical chemistry. For clinical chemistry, or for non-invasive sensing through skin, it is often necessary to obtain quantitative information in highly scattering media. Lifetime-based sensing can be used to obtain quantitative measurements in turbid media. We describe frequency-domain lifetime measurements in intralipid suspension, and present a reliable technique which allows phase-modulation lifetime measurements of fluorophores dispersed within or localized within intralipid. Lifetimes can be measured using an intensity decay law which accounts for the time delays and pulse-broadening effects of multiple light scattering events occurring in the intralipid. Alternatively, the phase and modulation measurements can be performed relative to a reference fluorophore of known lifetime. This approach provided reliable lifetime data for a pH-sensitive fluorophore contained within a microcuvette 4 mm under the surface of an intralipid suspension.
ChemInform Abstract: Novel Desulfurization of Thiocarbonyl Compounds into Their Carbonyl Compounds with Tertiary Butyl Thionitrate. (1987)

Abstract tert‐Butyl thionitrate (I) exists in three isomeric forms (Ia) ‐ (Ic).
Effect of PD fluid instillation on the peritonitis‐induced influx and bacterial clearing capacity of peritoneal cells (2001)

No differences were observed in bacterial clearing capacity, leukocyte influx and mesothelial cell number after a 2 week exposure of the peritoneal cavity to Gambrosol vs PD-Bio.
Can hematological parameters discriminate malaria from nonmalarious acute febrile illness in the tropics? (2004)

A total of 184 patients were included in the study and 70 (38%) had a positive peripheral smear for malarial parasite. Thrombocytopenia alone (platelet countless than 150,000/mm3) was a predictor for malaria (Sn 60%, Sp 88%, LR+ 5.04) and in combination with anemia (Hb < 10 g/dl) it was next best parameter (Sn 69%, Sp 74%, LR+ 2.77). RDW and leukocyte count were not predictive. The conclusion of this study is that the presence of thrombocytopenia in a patient with acute febrile illness increases the probability of malarial infection.
Ketamine-HCI as a Suitable Anesthetic for Endocrine, Metabolic, and Cardiovascular Studies in Macaca fascicularis Monkeys (1981)

Ketamine-HCl has been reported, depending on experimental conditions and dosage given, to have significant cardiovascular and endocrine effects in some species. However, previous studies in primates have inadequately distinguished between animal handling and ketamine effects. We, therefore, examined the effects of various doses of ketamine (0, 5, 10, 15, and 20 mg/kg) on mean arterial blood pressure and on plasma insulin, glucose, and cortisol concentrations in 10 chronically cannulated Macaca fascicularis monkeys which had been acclimated to restraining chairs. Each monkey received three different doses of ketamine according to a balanced incomplete block design. Ketamine anesthesia produced no significant changes in plasma insulin, glucose, or cortisol concentrations nor did it affect mean arterial blood pressure. In addition, the effects of ketamine-HCl on endocrine responses to insulin-induced hypoglycemia were examined in four animals according to a cross-over design. These animals also had chronically maintained cannulas and had been acclimated to restraining chairs. Plasma glucose concentrations, as well as plasma ACTH, growth hormone, and Cortisol responses in ketamine-anesthetized animals receiving an insulin challenge were no different from those in unanesthetized control animals. Thus, our studies indicate that ketamine-HCl does not perturb these particular hormonal systems in M. fascicularis monkeys.
Cell adhesion molecules in Drosophila synapse development and function (2012)

Synapse is a highly specialized inter-cellular structure between neurons or between a neuron and its target cell that mediates cell-cell communications. Ample results indicate that synaptic adhesion molecules are critically important in modulating the complexity and specificity of the synapse. And disruption of adhesive properties of synapses may lead to neurodevelopmental or neurodegenerative diseases. In this review, we will use the Drosophila NMJ as a model system for glutamatergic synapses to discuss the structure and function of homophilic and heterophilic synaptic adhesion molecules with special focus on recent findings in neurexins and neuroligins in Drosophila.
Evaluation of Two Iterative Techniques for Reducing Metal Artifacts in Computed Tomography (2011)

http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11101782/-/DC1.
Interaction of Oxidative Stress and Inflammatory Response in Coronary Plaque Instability (2003)

Objective— C-reactive protein (CRP), a predictor of cardiovascular events, localizes in atherosclerotic arteries and exerts proinflammatory effects on vascular cells. Reactive oxygen species (ROS) have been implicated in atherogenesis and plaque instability. Methods and Results— Expressional pattern of CRP in directional coronary atherectomy specimens from 39 patients was examined. Characteristics of histological plaque instability and higher levels of serum CRP and fibrinogen were associated with the CRP immunoreactivity. In situ hybridization revealed the presence of CRP mRNA in coronary vasculature. Furthermore, the expression of CRP mRNA and protein was detected in cultured human coronary artery smooth muscle cells (CASMCs) by reverse transcriptase–polymerase chain reaction and Western blotting. In addition, CRP was frequently colocalized with p22 phox , an essential component of NADH/NADPH oxidase, which is an important source of ROS in vasculature. Moreover, the incubation of cultured CASMCs with CRP resulted in the enhanced p22 phox protein expression and in the generation of intracellular ROS. Conclusions— The expression of CRP in coronary arteries was associated with histological and clinical features of vulnerable plaque, and it had a prooxidative effect on cultured CASMCs, suggesting that it might play a crucial role in plaque instability and in the pathogenesis of acute coronary syndrome via its prooxidative effect.
Pressure-hydrogenation of Organic Compounds by Molybdenum Sulfide Catalyst. X (1961)

Catalytic reduction of p-toluenesulfonic acid derivatives and p-toluenesulfinic acid with molybdenum sulfide catalyst at high prsssure and their reductive cleavages have been investigated.Although the temperature of reaction became higher in order of p-toluenesulfonyl chloride, sulfinic acid, ethyl ester, amide, 4nd phenyl ester, even the last phenyl ester was almost completely cleaved to toluene at 300°C and it was indicated that the reduction was proceeded much easier than sulfonic acid.The final product was toluene and the yield was higher than 80% in case of amide and phenyl ester but the yield was lower in case of chloride, ethyl ester and sulfinic acid.By consideration of the fact that p-thiocresol and di-p-tolyl disulfide were obtained as the intermediate products in each case, the reductive cleavage was assumed to proceed through the following reductive condensation reactions: p-toluenesulfonic acid derivatives→sulfinic→acid→disulfide→thiocresol→toluene.
A Build-in Self-Test Technique for RF Low-Noise Amplifiers (2008)

A built-in self-test (BIST) technique suitable for RF low-noise amplifiers (LNAs) is presented in this paper. With fully integrated amplitude detectors and logarithmic amplifiers, the BIST module can be employed as a generic platform for gain extraction of the device-under-test (DUT) without expensive testing instruments, while maintaining a reasonable hardware overhead and minimum loading effects to the DUT. Using a 0.18-mum CMOS process, a 5-GHz variable-gain LNA with the proposed BIST module is implemented. Based on the experimental results, on-chip gain extraction of the LNA has been demonstrated with an error less than 1 dB for various gain modes. The additional chip area required for the BIST functionality measures 0.042 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , which is considerably small compared with the physical size of the RF amplifiers.
Magnesium Alloys Containing Rare Earth Metals: Structure and Properties (2003)

Preface. Introduction. Physico-Chemical Interaction Between Magnesium and Rare-earth Metals. Decomposition of the Supersaturated Solid Solutions in Mg-RE Alloys. Peculiarities of the Plastic Deformation and Recrystallization in Mg-RE Alloys. Effect or Rare-earth Metals on Mechanical and Some Other Properties of Magnesium. Commercial Magnesium Alloys with Rare-earth Metals, Their Compositions and Properties. Conclusion. References. Subject. Index.
Factor Va-factor Xa interaction. Effects of phospholipid vesicles of varying composition (1982)

The interaction between factor Xa and factor Va was investigated both in solution and in the presence of phospholipid vesicles with varying contents of phosphatidylserine. The binding parameters were inferred from the kinetics of prothrombin activation. Factor Xa and factor Va form in solution an equimolar complex with a dissociation constant of 3.3 X 10(-9) M. Phospholipid vesicles promote the formation of the factor Xa-Va complex. The Kd of complex formation is dependent on both the phospholipid concentration and the composition of the phospholipid vesicle. For the interaction between factor Xa and factor Va in the presence of phospholipid vesicles containing 40 mol % dioleoylphosphatidylserine (DOPS) and 60 mol % dioleoylphosphatidylcholine (DOPC), the Kd increases linearly with increasing phospholipid concentration. In the presence of 10 microM phospholipid (DOPS/DOPC, 40/60 mol/mol) Kd = 3 X 10(-11) M. When the mole percentage of DOPS in the phospholipid vesicles is lowered from 20 to 5 mol %, there is a gradual increase of the Kd. In the presence of 10 microM phospholipid vesicles containing 5 mol % DOPS and 95 mol % DOPC Kd = 2.8 X 10(-10) M. The Kd measured in the presence of phospholipid vesicles containing 5 mol % DOPS and 95 mol % DOPC is independent of the phospholipid concentration. Two models are discussed that can quantitatively explain the effect of phospholipid vesicles on the complex formation between factor Xa and factor Va. Studies on the effect of the polypeptides with Mr 80 000 and Mr 94000 of which factor Va is composed on the Kd of the factor Xa-Va complex suggest that factor Xa binding to factor Va requires a Ca2+-mediated interaction between the two polypeptides.
A diversity combining DS/CDMA system with convolutional encoding and Viterbi decoding (1995)

Averaged diversity combining is applied to an asynchronous DS/CDMA system using convolutional encoding and Viterbi decoding. A cyclic redundancy check (CRC) code is included in the scheme to trigger retransmission requests. Multiple received packets are combined on a bit by bit basis to form a single, more reliable packet. The error correcting decoder operates on the combined packet, as opposed to the most recently received individual packet (e.g., as in a type-I hybrid ARQ protocol), substantially increasing the probability of acceptance with each additional transmission. We show that the proposed technique allows a significant increase in the CDMA system capacity, throughput, and reliability.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Hospital Use and Survival among Veterans Affairs Beneficiaries (2003)

The marked decline in VA hospital use from 1994 through 1998 did not curtail access to needed services and was not associated with serious consequences for chronically ill VA beneficiaries.
Effects of anesthesia and vehicle injection on circulating blood elements in C3H/HeN male mice. (2004)

The induction and maintenance of general anesthesia can lead to profound alterations of many organ systems, especially the cardiovascular, pulmonary, and nervous systems. Moreover, distinct from their cardiopulmonary effects, certain anesthetics can induce physiologic and behavioral changes, which may persist after recovery from anesthesia. Knowledge of the effects of anesthesia and anesthetic agents on hematologic measurements is important. Although the effects of anesthesia were clinically unapparent, the effect on levels of circulating blood elements was an important determinant for the results of our study. We sought to evaluate the effect of anesthesia and vehicle injection on the levels of circulating blood elements in C3H/HeN male mice. We used an automated hematology system to obtain complete blood counts with differentials in anesthetized and unanesthetized mice receiving subcutaneous injections of polyethylene glycol (PEG-400). Two days after a 30-min exposure to isoflurane anesthesia, mean white blood cell counts had deceased by 15.4%, mean neutrophil counts had decreased by 26.9%, and mean platelet counts by 11.2% compared with levels in unanesthetized mice. Our results indicate that the effect of anesthesia is an important consideration when circulating blood elements in mice must be measured.
Influence of Systematic Biases Associated with Genotype and Sex on Prediction of Lean Mass and Carcass Value in U.S. Pigs (1997)

Much work has been done on developing equations for estimating fat-free lean mass andcarcass value in pigs (Akridge et al., 1992; and Boland et al., 1995). However, most equationscurrently in use have not been evaluated for the extent to which they account for genotype and sexdifferences in carcass composition. Packers produce pork products from pigs of diverse genotypicbackgrounds and different sexes. Therefore, any realistic attempt to develop an unbiased evaluationsystem should account for a high percentage of the genotype and sex differences. Equations forpredicting lean mass and carcass value use a variety of evaluation technologies. These include rulers,optical probes, ultrasonic imaging, and electromagnetic scanning. Regression equations are used toconvert measurement readings from these technologies into lean mass and carcass value (Forrest et al.,1989). The objective of this study was to examine the influence of biases associated with genotype andsex on prediction of fat free lean mass and carcass value in pigs, and measures that can be put in placeto minimize biases.
Defect engineering of metal oxide semiconductors (2010)

Defects in semiconductors have been studied for many years, with a view toward controlling their behavior through various forms of defect engineering. In the Si-based microelectronics industry, numerous methods to characterize and control the behavior of defects have been developed, including novel techniques such as co-implantation, millisecond annealing, photostimulation and surface engineering. Closely related, yet unique defect engineering efforts have also been made for non-Si based microelectronic applications as well. The accumulated knowledge stemmed from microelectronics should also be able to be extended to metal oxide semiconductors, where promising applications (e.g., gas sensors and photocatalysts) are gaining increased interest. In particular, the use of surface engineering has been extended to titanium dioxide, opening up new possibilities of defect control. For further investigation of these effects, sulfur has been chosen as a surface controlling adsorbate, which can be used to manipulate the surface states. The successful deposition of the element through electrochemical means has been demonstrated on silicon and titanium dioxide substrates. In addition, experimental and computational studies on the behavior of the cation species in titanium dioxide using isotopic tracers have also been carried out, with an emphasis on the effect of surface states. It follows that the surface state can indeed influence the cation defect behaviors in a significant manner, which in turn affects the self-diffusion profiles.
Investigation of fault modes of voltage-fed inverter system for induction motor drive (2003)

The authors describe a systematic investigation into the various fault modes of a voltage-fed pulse-width-modulated (PWM) inverter system for induction motor drives. All the fault modes were identified, and a preliminary mathematical analysis was made for the key fault types-namely, input supply single line to ground fault, rectifier diode short circuit, inverter transistor base drive open, and inverter transistor short circuit conditions. The predicted fault performances were substantiated by a simulation study. The study was used to determine stresses in power circuit components and to evaluate satisfactory postfault steady-state operating regions. The results are equally useful for better protection system design and easy fault diagnosis.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Iron(II, III)-chlorin and -isobacteriochlorin complexes. Models of the heme prosthetic groups in nitrite and sulfite reductases: means of formation and spectroscopic and redox properties (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIron(II, III)-chlorin and -isobacteriochlorin complexes. Models of the heme prosthetic groups in nitrite and sulfite reductases: means of formation and spectroscopic and redox propertiesAlan M. Stolzenberg, Steven H. Strauss, and R. H. HolmCite this: J. Am. Chem. Soc. 1981, 103, 16, 4763–4778Publication Date (Print):August 1, 1981Publication History Published online1 May 2002Published inissue 1 August 1981https://pubs.acs.org/doi/10.1021/ja00406a018https://doi.org/10.1021/ja00406a018research-articleACS PublicationsRequest reuse permissionsArticle Views515Altmetric-Citations126LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts