gebhart/patrepeval huggingface dataset:
Generalized quadratic weights for asymptotic regulator properties (1979)

This paper describes a generalized quadratic weight selection procedure based on asymptotic modal properties of linear-quadratic regulators as control weights tend to zero. Explicit formulas are developed for weighting matrices which produce an asymptotic eigenstructure consisting of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p \leq n-m</tex> finite modes, with the rest tending to infinity in selectable Butterworth patterns or determined by other secondary design considerations.
Hydrogen Peroxide Alters Mitochondrial Activation and Insulin Secretion in Pancreatic Beta Cells (1999)

The effects of a transient exposure to hydrogen peroxide (10 min at 200 microM H(2)O(2)) on pancreatic beta cell signal transduction and insulin secretion have been evaluated. In rat islets, insulin secretion evoked by glucose (16.7 mM) or by the mitochondrial substrate methyl succinate (5 mM) was markedly blunted following exposure to H(2)O(2). In contrast, the secretory response induced by plasma membrane depolarization (20 mM KCl) was not significantly affected. Similar results were obtained in insulinoma INS-1 cells using glucose (12.8 mM) as secretagogue. After H(2)O(2) treatment, glucose no longer depolarized the membrane potential (DeltaPsi) of INS-1 cells or increased cytosolic Ca(2+). Both DeltaPsi and Ca(2+) responses were still observed with 30 mM KCl despite an elevated baseline of cytosolic Ca(2+) appearing approximately 10 min after exposure to H(2)O(2). The mitochondrial DeltaPsi of INS-1 cells was depolarized by H(2)O(2) abolishing the hyperpolarizing action of glucose. These DeltaPsi changes correlated with altered mitochondrial morphology; the latter was not preserved by the overexpression of the antiapoptotic protein Bcl-2. Mitochondrial Ca(2+) was increased following exposure to H(2)O(2) up to the micromolar range. No further augmentation occurred after glucose addition, which normally raises this parameter. Nevertheless, KCl was still efficient in enhancing mitochondrial Ca(2+). Cytosolic ATP was markedly reduced by H(2)O(2) treatment, probably explaining the decreased endoplasmic reticulum Ca(2+). Taken together, these data point to the mitochondria as primary targets for H(2)O(2) damage, which will eventually interrupt the transduction of signals normally coupling glucose metabolism to insulin secretion.
Self-Assembly of a Polyrotaxane Containing a Cyclic “Bead” in Every Structural Unit in the Solid State:  Cucurbituril Molecules Threaded on a One-Dimensional Coordination Polymer (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSelf-Assembly of a Polyrotaxane Containing a Cyclic "Bead" in Every Structural Unit in the Solid State: Cucurbituril Molecules Threaded on a One-Dimensional Coordination PolymerDongmok Whang, You-Moon Jeon, Jungseok Heo, and Kimoon KimView Author Information Department of Chemistry and Center for Biofunctional Molecules Pohang University of Science and Technology San 31 Hyojadong, Pohang, 790-784, South KoreaCite this: J. Am. Chem. Soc. 1996, 118, 45, 11333–11334Publication Date (Web):November 13, 1996Publication History Received9 May 1996Published online13 November 1996Published inissue 13 November 1996https://pubs.acs.org/doi/10.1021/ja961551lhttps://doi.org/10.1021/ja961551lrapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views2472Altmetric-Citations218LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Coordination polymers,Copper,Ions,Metals,Molecules Get e-Alerts
A simple clamped ZVS PWM converter (2002)

A buck derived power converter which accomplishes clamped zero voltage switching at both turn on and turn off transitions while maintaining low core and conduction losses is described. The converter provides output isolation and can be simply extended to multi-output applications and other-than-buck topologies. The design's simplicity also makes it an ideal candidate for parallel interleaved multiphase power converters for high density, high frequency applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Reduction of Prostaglandin Enone Intermediates with Aluminium Isopropoxide (1974)

Abstract Because of their enormous therapeutic potential in several, diverse, disease areas the natural prostaglandins and their analogues have been the synthetic target of a large amount of chemical effort in recent years1. A crucial step in many of the successful syntheses is the reduction of an α, β-unsaturated ketone to a mixture of allylic alcohols. For example in Corey's synthesis2 of the natural compounds the enone (Ia) is reduced to the enols (IIa) and (IIIa). This is best achieved using bulky borohydride reducing agents3 with the additional advantage that a preponderance of the required isomer (IIa) is obtained. However, in our experience use of the more convenient sodium or zinc borohydrides is often complicated by the fact that 1,4-reduction occurs to give the saturated ketone and sometimes saturated alcohols.
Effect of Nanoscale Curvature of Single-Walled Carbon Nanotubes on Adsorption of Polycyclic Aromatic Hydrocarbons (2007)

Liquid-phase adsorption of tetracene and phenanthrene on a single-walled carbon nanotube (SWCNT) was examined. Tetracene adsorption was more than six times greater than that of phenanthrene. X-ray photoelectron spectroscopic examination clearly showed that tetracene and phenanthrene molecules efficiently coated the SWCNT external surfaces. The remarkable difference between the adsorption amounts of tetracene and phenanthrene was caused by the nanoscale curvature effect of the tube surface, resulting in a difference in the amount of contact between the molecule and the tube surface. The adsorption of tetracene and phenanthrene caused a significant higher frequency shift in the radial breathing mode (RBM) of the Raman band of the SWCNT, indicating an intensive pi-pi interaction between these polycyclic aromatic hydrocarbons and the external SWCNT surface.
High Rates and Substrate Selectivities in Water by Polyvinylimidazoles as Transaminase Enzyme Mimics with Hydrophobically Bound Pyridoxamine Derivatives as Coenzyme Mimics (2009)

Free-radical polymers of 4-vinylimidazole and copolymers with 1-dodecyl-4-vinylimidazole were used as enzyme mimics to transaminate pyruvic acid to alanine, phenylpyruvic acid to phenylalanine, and indole-3-pyruvic acid to tryptophan in water at pH 7.5 and 20 degrees C using pyridoxamines carrying hydrophobic side chains as coenzyme mimics. The best enzyme mimic accelerated the transamination of indole-3-pyruvic acid by a factor of 4 million relative to the rate without the polymer, a higher rate ratio than we had previously achieved with a polyaziridine-based enzyme mimic. The properties of various polyvinylimidazoles were compared, including those prepared with the RAFT modification of the polymerization process.
Fully automatic and reference-marker-free image stitching method for full-spine and full-leg imaging with computed radiography (2004)

Full-leg and full-spine imaging with standard computed radiography (CR) systems requires several cassettes/storage phosphor screens to be placed in a staggered arrangement and exposed simultaneously to achieve an increased imaging area. A method has been developed that can automatically and accurately stitch the acquired sub-images without relying on any external reference markers. It can detect and correct the order, orientation, and overlap arrangement of the subimages for stitching. The automatic determination of the order, orientation, and overlap arrangement of the sub-images consists of (1) constructing a hypothesis list that includes all cassette/screen arrangements, (2) refining hypotheses based on a set of rules derived from imaging physics, (3) correlating each consecutive sub-image pair in each hypothesis and establishing an overall figure-of-merit, (4) selecting the hypothesis of maximum figure-of-merit. The stitching process requires the CR reader to over scan each CR screen so that the screen edges are completely visible in the acquired sub-images. The rotational displacement and vertical displacement between two consecutive sub-images are calculated by matching the orientation and location of the screen edge in the front image and its corresponding shadow in the back image. The horizontal displacement is estimated by maximizing the correlation function between the two image sections in the overlap region. Accordingly, the two images are stitched together. This process is repeated for the newly stitched composite image and the next consecutive sub-image until a full-image composite is created. The method has been evaluated in both phantom experiments and clinical studies. The standard deviation of image misregistration is below one image pixel.
Some Travelling-wave Interactions in Semiconductors Theory and Design Considerations† (1966)

ABSTRACT A general analysis of the interaction of a slow wave with a drifting stream of carriers is presented, The slow wave has an associated electric field, and may be electromagnetic or acousto-electric in character. The effects of both collision and diffusion are included in the analysis. The vacuum travelling-wave tube and the acoustic semiconductor amplifier emerge as special cases. The results are used to evaluate the feasibility of obtaining net gain from the interaction of drifting carriers in a semiconductor with the electromagnetic wave guided by an external structure. The conditions which provide the best hope of success are identified. The required physical materials constants arc only partially known, but using the best available estimates the theory suggests that substantial gains should be attainable.
Growth and serial passage of Pneumocystis carinii in the A549 cell line (1984)

Pneumocystis carinii obtained from infected rats and patients was cultured in the A549 cell line, a presumptive alveolar type 2 cell line derived from a human lung carcinoma. Standard criteria were established for organism sampling, quantitation, and growth. The trophozoite form of P. carinii was a more sensitive indicator of growth than was the cyst. Rat P. carinii increased 10-fold in primary culture and could be serially passed three additional times to new cultures; success in growing human P. carinii was limited and appeared to be related to the quality of the specimen received for culture. Growth pattern experiments suggested that close interaction of P. carinii with the cell monolayer is an important step in the life cycle of the organism. Thus, the A549 culture system should be useful for in vitro studies of the immunobiology of P. carinii.
Capture-Replay Testing for Android Applications (2014)

With the widespread popularity of Android devices, the number of Android applications has increased dramatically in recent years. In order to assure the quality of the applications, Android testing has drawn extensive attention. This paper proposes an approach to automate the testing of Android applications based on the Capture and Replay method. Particularly, the user events of Android applications are captured and converted into Robotium test scripts that can be executed to replay the recorded actions of users. The approach also allows inserting assertions when capturing user interactions for verifying the outputs of Android UI components. A supporting tool is implemented to illustrate the usefulness of the proposed approach.
Platinum(<scp>II</scp>) Complexes with Porphyrin Ligands—Additive Cytotoxic and Photodynamic Effect (1994)

Tumoral destruction increases from 0% to 37% in the dark, and from 19% to 62% with subsequent IR irradiation, when instead of the free ligand 1 its platinum complex 2 is employed against tumor cells.
Issues Associated with and Recommendations for Using PCR To Detect Outbreaks of Pertussis (2002)

Two outbreaks of respiratory tract illness associated with prolonged cough occurring in 1998 and 1999 in New York State were investigated. A PCR test for Bordetella pertussis was primarily used by a private laboratory to confirm 680 pertussis cases. Several clinical specimens had positive culture results for B. pertussis during both outbreaks, which confirmed that B. pertussis was circulating during the outbreaks. However, testing by the New York State Department of Health reference laboratory suggested that some of the PCR results may have been falsely positive. In addition, features of the outbreak that suggested that B. pertussis may not have been the primary agent of infection included a low attack rate among incompletely vaccinated children and a significant amount of illness among patients testing PCR negative for B. pertussis. These investigations highlight the importance of appropriate clinical laboratory quality assurance programs, of the limitations of the PCR test, and of interpreting laboratory results in context of clinical disease.
Ammonia absorption on coal and oil fly ashes (1996)

Ammonia and urea based post-combustion NO{sub x} control technologies (e.g., SNCR, SCR) are becoming more common as utilities strive to meet more stringent NO{sub x} emission regulations. One issue associated with these technologies is the fate of ammonia slip. A portion of the NH{sub 3} slip will be absorbed by the fly ash. Depending on the concentrations of ammonia in the ash, this may pose odor problems while handling the ash, and impact the disposal and marketability of the ash. This paper presents the results of a bench-scale study conducted to characterize NH{sub 3} absorption by fly ash. The experiment investigated NH{sub 3} absorption as a function of ash type (four coal ashes, two oil ashes), exposure time, temperature, and NH{sub 3} concentration.
Quantitative photodecarbonylation of formanilides: a new photosensitive protecting group for anilines (1972)

B. K. Barnett and T. D. Roberts, J. Chem. Soc., Chem. Commun., 1972, 758 DOI: 10.1039/C39720000758
The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed (1998)

FIG. 1. Calcemic and phosphatemic biological actions of vitamin D in mammals.(A) Effects of vitamin D and its metabolites to ensure skeletal integrity, especially when calcium is limiting.(Central open box) Vitamin D 3 , obtained from diet or derived from sunlight-initiated photobiogenesis in skin, is converted via two hydroxylation reactions to the 1,25(OH) 2 D 3 hormonal form that circulates in blood.The final step in bioactivation of vitamin to hormone is catalyzed by the renal 1-OHase when stimulated by PTH under conditions of low calcium.(Lower portion) Integrated actions of the 1,25(OH) 2 D 3 metabolite, via binding to the intracellular VDR, to control calcium homeostasis in bone, intestine, kidney, and parathyroid as explained in the text.(Top left) Action of 1,25(OH) 2 D 3 -VDR in skin cell differentiation.(Top center) Conversion of 1,25(OH) 2 D 3 or the preceding 25(OH)D 3 metabolite to 24-hydroxylated forms in response to 1,25(OH) 2 D 3 -VDR induction of the 24-OHase gene.This conversion serves to initiate catabolism of the vitamin D molecule, but may also produce 24-hydroxylated metabolites with novel hormonal activity with respect to chondrocyte differentiation and bone mineralization (see text).(B) The vitamin D bioactivation-phosphate homeostatic loop: proposed novel roles for phosphatonin, the PEX gene product, and NPT2.(Left and lower portion) Under normal physiologic conditions, low PO 4 enhances the synthesis of 1,25(OH) 2 D 3 , which then acts through VDR to effect phosphate reclamation by suppressing PTH as well as inducing NPT2 and PEX gene expression.NPT2 acts directly to reabsorb PO 4 , while the PEX enzyme eliminates phosphatonin.(Top right) Tumor-induced osteomalacia and XLH each elicit increased phosphatonin, an uncharacterized phosphaturic hormone that is postulated to inhibit both NPT2 and the 1-OHase, to cause severe phosphate wasting.
Reconstitution of simian virus 40 DNA replication with purified proteins. (1990)

Replication of plasmid DNA molecules containing the simian virus 40 (SV40) origin of DNA replication has been reconstituted with seven highly purified cellular proteins plus the SV40 large tumor (T) antigen. Initiation of DNA synthesis is absolutely dependent upon T antigen, replication protein A, and the DNA polymerase alpha-primase complex and is stimulated by the catalytic subunit of protein phosphatase 2A. Efficient elongation of nascent chains additionally requires proliferating cell nuclear antigen, replication factor C, DNA topoisomerase I, and DNA polymerase delta. Electron microscopic studies indicate that DNA replication begins at the viral origin and proceeds via intermediates containing two forks that move in opposite directions. These findings indicate that the reconstituted replication reaction has many of the characteristics expected of authentic viral DNA replication.
A facile solvent-free synthesis route for the assembly of a highly CO<sub>2</sub> selective and H<sub>2</sub>S tolerant NiSIFSIX metal–organic framework (2015)

Here we report a solvent-free route for the synthesis of an H<sub>2</sub>S stable and highly CO<sub>2</sub> selective porous hybrid material, namely (NiSiF<sub>6</sub>(pyz)<sub>2</sub>) MOF.
Modeling Diverse Communities of Marine Microbes (2010)

Biogeochemical cycles in the ocean are mediated by complex and diverse microbial communities. Over the past decade, marine ecosystem and biogeochemistry models have begun to address some of this diversity by resolving several groups of (mostly autotrophic) plankton, differentiated by biogeochemical function. Here, we review recent model approaches that are rooted in the notion that an even richer diversity is fundamental to the organization of marine microbial communities. These models begin to resolve, and address the significance of, diversity within functional groups. Seeded with diverse populations spanning prescribed regions of trait space, these simulations self-select community structure according to relative fitness in the virtual environment. Such models are suited to considering ecological questions, such as the regulation of patterns of biodiversity, and to simulating the response to changing environments. A key issue for all such models is the constraint of viable trait space and trade-offs. Size-structuring and mechanistic descriptions of energy and resource allocation at the individual level can rationalize these constraints.
Identifying architectural technical debt in Android applications through automated compliance checking (2018)

By considering the fast pace at which mobile applications need to evolve, Architectural Technical Debt results to be a crucial yet implicit factor of success. In this research we present an approach to automatically identify Architectural Technical Debt in Android applications. The approach takes advantage of architectural guidelines extraction and modeling, architecture reverse engineering, and compliance checking. As future work, we plan to fully automate the process and empirically evaluate it via large-scale experiments.
Factors Affecting Guardianship Practices for Young Adults with Disabilities (2002)

Some contend developing self-determination in young adults with disabilities is the ultimate goal of education and promoting it may lead to improved postschool outcomes. Although there are efforts to promote self-determination, the results may be negated as an individual's right to make decisions are eliminated when a guardianship is imposed. This research is the first to examine guardianship as it affects young adults with disabilities. Two hundred and twenty-one court files were reviewed across nine jurisdictions in Michigan. Overall, 120 plenary guardians and 101 partial guardians were appointed. Distinctions between the powers of plenary and partial guardians, however, were often found to be minimal. Guardianship is a complex issue with many significant questions in need of answers.
Minimization and Reuse of Pesticide Rinsates (1992)

Prior to 1985, pesticide waste management was not well defined. National EPA/NACA Pesticide Waste Management Workshops in 1985 and 1987 were held to identify, define and outline national pesticide waste handling, processing, storage and disposal problems. FIFRA '88 provided guidance for EPA, pesticide producers and users. University and chemical industry researchers have concentrated efforts on reducing pesticide rinsate and waste formation and disposal for both aerial and ground application. Developments of direct injection of full strength pesticides, expanded use of returnable containers, standardization of container openings, and improvements in container rinsing and closed mixing systems look encouraging. Direct oil and carbon filter/ozone processing of pesticide waste is being used by California applicators. A widespread/practical method currently used is reuse of rinsates as part of make-up water for subsequent applications or field rinsing and spraying back on the target area.
ASSIST - Automated System for Surgical Instrument and Sponge Tracking (2008)

Every surgical item used during surgery (e.g., sponges) must be accounted for after surgery to ensure that none of these items is left inside the patient. Despite the numerous precautions in place, in approximately 1 in 1500 cases, something gets left behind inside the patient's body. This paper presents ASSIST, an automated system for surgical instrument and sponge tracking that increases the safety of surgical procedures. ASSIST utilizes RFID (Radio Frequency Identification) technology to aid in accounting for all items used during surgery. The design takes into account safety, simplicity, ease of deployment, and ease of use. An initial evaluation utilizing RFID-tagged sponges demonstrates that ASSIST can reliably track surgical sponges with minimal impact to current operating room procedures. Sources of error that can impact the reliability of the system are also discussed.
The research progress of Chuanbeimu (2012)

In order to ensure sufficient and reasonable use, a review on textual research, origin and place of plant, chemical composition, extraction technology and pharmacological research of Chuanbeimu is carried out, that provides the reference for the study on quality standard of Chuanbeimu, the development of non medicinal part and new drug resources.