gebhart/patrepeval huggingface dataset:
Adaptive video on demand (1994)

In this paper we formulate the problem of Video on Demand (VOD) from a resource allocation perspective. In particular, we introduce the decision element into a movie vending environment, which complements the current approaches. In contrast with more the traditional resource allocation problems (such as machine scheduling and call control), the problem possesses the distinctive batching property, which stands for the feasibility of several requests being served by one resource (channel). We investigate the problem in an on-line fashion, namely, having to accept or reject a request for a movie without the knowledge of future requests. We show upper and lower bounds on the competitive ratio of deterministic on-line movie scheduling algorithms for a variety of scenarios (an algorithm is called competitive if it performs, up to a constant factor, as well as its off-line, clairvoyant counterparts for the same problem). In particular, for the natural case of refusal by choice with delayed notification, we present a class of algorithms that exhibit, under certain conditions, an asymptotically optimal behavior.
<i>Helicobacter pylori</i> Infection Up‐regulates Gland Mucous Cell‐Type Mucins in Gastric Pyloric Mucosa (2003)

In addition to the synthesis of GMC mucins increasing reversibly, their metabolism or release may also increase reversibly in H. pylori-associated gastritis. The up-regulation of the expression of gastric GMC mucins may be involved in defense against H. pylori infection in the gastric surface mucous gel layer and on the gastric mucosa.
Plasma deposition—Impact of ions in plasma enhanced chemical vapor deposition, plasma enhanced atomic layer deposition, and applications to area selective deposition (2020)

In this paper, the emerging role of ionic species in plasma assisted chemical deposition processes is discussed in detail for commemorating the Career of John Coburn, who studied the role of ionic species in plasma etching processes forty years ago. It is shown that, in both plasma enhanced chemical vapor deposition and plasma enhanced atomic layer deposition processes, plasma ions can play a major role in tuning a wide range of physical properties of thin films. In both processes, the possibility of extracting plasma ions with a tunable incident kinetic energy driven on the substrate surface is shown to provide a valuable additional degree of freedom in plasma processing. While a too large incident kinetic energy of plasma ions may have damaging effects linked to surface sputtering and atomic peening, a relatively low energy ion bombardment ensures a substantial improvement of thin film purity and the effective tuning of their microstructural properties. This phenomenon is attributed to the synergetic effect boosting momentum transfer and chemical reactivity among radicals and ionic plasma species, which, in turn, modulates plasma-surface interactions. Taking advantage of these tunable physical properties opens up the way to a large array of pathways for selective deposition processes in both 2D and 3D nanoscale microstructures.
A novel integrated interconnect network for RF switch matrix applications (2004)

In this paper, a new integrated RF interconnect network is presented. The circuit is printed on a double sided alumina substrate, eliminating the need to use multilayer manufacturing technology. The interconnect network employs finite ground coplanar (FGC) lines and vertical 3-via transitions and can be easily integrated with semiconductor and MEMS switches to form a switch matrix. Simulation and experimental results are presented for a 3/spl times/3 interconnect network. The measured results show a return loss of -20 dB and an isolation of better than -40 dB up to 30 GHz.
Diagnosis and classification of hematologic malignancies on the basis of genetics (2017)

Genomic analysis has greatly influenced the diagnosis and clinical management of patients affected by diverse forms of hematologic malignancies. Here, we review how genetic alterations define subclasses of patients with acute leukemias, myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPNs), non-Hodgkin lymphomas, and classical Hodgkin lymphoma. These include new subtypes of acute myeloid leukemia defined by mutations in <i>RUNX1</i> or <i>BCR-ABL1</i> translocations as well as a constellation of somatic structural DNA alterations in acute lymphoblastic leukemia. Among patients with MDS, detection of mutations in <i>SF3B1</i> define a subgroup of patients with the ring sideroblast form of MDS and a favorable prognosis. For patients with MPNs, detection of the <i>BCR-ABL1</i> fusion delineates chronic myeloid leukemia from classic <i>BCR-ABL1</i><sup>-</sup> MPNs, which are largely defined by mutations in <i>JAK2</i>, <i>CALR</i>, or <i>MPL</i> In the B-cell lymphomas, detection of characteristic rearrangements involving <i>MYC</i> in Burkitt lymphoma, <i>BCL2</i> in follicular lymphoma, and <i>MYC/BCL2/BCL6</i> in high-grade B-cell lymphomas are essential for diagnosis. In T-cell lymphomas, anaplastic large-cell lymphoma is defined by mutually exclusive rearrangements of <i>ALK</i>, <i>DUSP22/IRF4</i>, and <i>TP63</i> Genetic alterations affecting <i>TP53</i> and the mutational status of the immunoglobulin heavy-chain variable region are important in clinical management of chronic lymphocytic leukemia. Additionally, detection of <i>BRAF</i>V600E mutations is helpful in the diagnosis of classical hairy cell leukemia and a number of histiocytic neoplasms. Numerous additional examples provided here demonstrate how clinical evaluation of genomic alterations have refined classification of myeloid neoplasms and major forms of lymphomas arising from B, T, or natural killer cells.
Optimization of protocol for sequencing of difficult templates. (2010)

In this paper, we have fine-tuned a DNA sequencing protocol suitable for a wide range of difficult templates. The primary goal was to evaluate a number of parameters--such as various dye terminator mixes in the presence or absence of additives, the amount of DNA or primer, and cycling protocols--about the effectiveness of reading through complex regions. We showed that the modification of a published protocol leads to significant (75%) cost reduction without forfeiting quality of the data. In the recommended protocol, we used betaine as a standard additive, but better results can be obtained when betaine and Reagent A are mixed in an equivalent ratio.
Sea Ice Thrust Structures (1958)

Abstract Unusual thrust structures in thin sea ice sheets were observed in Labrador and Greenland. These structures are the result of thin ice sheets being of wind and waves. When thicker pack ice is subjected to these same forces pressure ridges result.
Measurement placement algorithms for state estimation when the number of phasor measurements by each PMU is limited (2008)

It is essential for Energy Management Systems (EMS) applications and control centre technologies that the measurements allow monitoring of the power system. An important tool for the EMS is state estimation which makes it possible to estimate the state variables of the power system based on these measurements. The measurements should allow observability of the power system which means they can be used to describe the system. The objective of the paper is to develop an algorithm for placement of PMUs in order to make the system observable. The novelty is that a limit on the number of measurements each PMU can make is introduced. The number of PMUs needed to make the network observable will therefore depend on the maximum number of measurements each PMU can make. The algorithm is tested on three IEEE test networks.
Remote detection of methane with a 166-μm diode laser (1992)

High-sensitivity real-time remote detection of methane in air with a 1.66-microm distributed-feedback diode laser operating at room temperature is demonstrated by laboratory simulations. The laser current was modulated at a high frequency of ~5 MHz, and the laser-center frequency was locked onto a methane-absorption line. The laser light directed toward the probed region was received after one-way transmission or further reflection from a topographic target. The methane absorption was detected by the second-harmonic component in the optical-power variation. The minimum-detectable concentration-path-length product in the transmission scheme was 0.3 part in 10(6) m for a signal averaging time of 1.3 s. In the reflection scheme, the amount of methane could be measured from the ratio of the fundamental and second-harmonic signal intensities independently of the received power.
An unified approach to controls for unbalanced compensation in active magnetic bearings (2002)

This paper investigates the control for unbalanced compensation in active magnetic bearings from a viewpoint of output regulation. In an analytical study, the complex-variable description is used, which makes the manipulation of equations easier. A general form of the controller achieving displacement, current or force regulation is presented. The derived controllers in a complex-variable form are converted into two types of real-variable representations for actual implementation: the state equation and convolution integral. It clarifies the equivalence between the independently developed control methods.
Kron's reduction method applied to the time stepping finite element analysis of induction machines (1995)

The behavior of large induction motors during transient as well as steady state running conditions is of significant interest to the power industry. A variety of analytical predictive tools are employed to aid the design and predict their operation under transient and steady state conditions. This paper presents a strategy to reduce the required running time in order to make a parametric study of induction machines such as the assessment of different design options feasible. This is accomplished by reducing the number of finite element equations that must be solved while maintaining the same level of accuracy of solutions. This method is based on Kron's network reduction work for linear systems and has successfully been applied to large lumped parameter model of transformers. This paper illustrates the reduction method by comparing the flux density in the air gap for a complete FEM model of an induction machine to that of the reduced model. The results are essentially identical with a reduction in computational time of approximately 71%.
ORAL ENTERIC VACCINES—CLINICAL TRIALS (1991)

Oral enteric vaccines are reviewed with particular reference to cholera and typhoid. Enterotoxigenic E. coli, Shigella and Rotavirus vaccines are also considered. Clinical trials of those potentially useful vaccines are surveyed.
Molecular Imaging of the Initial Inflammatory Response in Atherosclerosis (2009)

Noninvasive ultrasound molecular imaging of endothelial activation can detect lesion-prone vascular phenotype before the appearance of obstructive atherosclerotic lesions.
BLIND SPATIAL SUBTRACTION ARRAY WITH INDEPENDENT COMPONENT ANALYSIS FOR HANDS-FREE SPEECH RECOGNITION (2006)

IWAENC2006: the 10th International Work Shop on Acoustic Echo and Noise Control, September 12-14, 2006, Paris, France.
Piggybacking Network Functions on SDN Reactive Routing (2017)

This paper explores the potential of enabling SDN security and monitoring services by piggybacking on SDN reactive routing. As a case study, we implement and evaluate a piggybacking based intrusion prevention system called SDN-Defense. Our study of university WiFi traffic traces reveals that up to 73% of malicious flows can be detected by inspecting just the first three packets of a flow, and 90% of malicious flows from the first four packets. Using such empirical insights, we propose to forward the first K packets of each new flow to an augmented SDN controller for security inspection, where K is a dynamically configurable parameter. We characterize the cost-benefit trade-offs of SDN-Defense using real wireless traces and discuss potential scalability issues. Finally, we discuss other applications which can be enhanced by using our proposed piggybacking approach.
Agonist monoclonal antibodies against HGF receptor protect cardiac muscle cells from apoptosis (2010)

Hepatocyte growth factor (HGF), a pleiotropic cytokine with mitogenic, motogenic, morphogenic, and antiapoptotic effects in various cell types, is a cardioprotective growth factor that can counteract the loss of cardiomyocytes usually observed in cardiac diseases. HGF is a quite unstable molecule in its biologically active heterodimeric form. Since all HGF-induced biological responses are mediated by its high-affinity tyrosine kinase receptor (Met/HGF-R) encoded by the Met gene, we asked whether a monoclonal antibody (MAb) that displays receptor full agonist activity could protect cardiac muscle cell lines from hydrogen peroxide-induced apoptosis. We report that the MAb efficiently inhibited hydrogen peroxide-induced cell shrinkage, DNA fragmentation, annexin V positivity, mitochondrial translocation of bax, and caspase activation. The MAb was thus able to counteract apoptosis evaluated by both morphological and biochemical criteria. The agonist activity of the MAb was mediated by Met/HGF-R, since a Met/HGF-R-specific short hairpin RNA (shRNA) inhibited both activation of transduction pathways and motility triggered by MAb DO-24. The protective antiapoptotic effect of MAb DO-24 was dependent on activation of the ras-MAPK Erk1/2 and phosphatidylinositol 3-kinase (PI3-kinase)-Akt transduction pathways, since it was abrogated by treatments with their specific pharmacological inhibitors, PD-98059 and wortmannin. Moreover, the MAb induced a motogenic, but not mitogenic, response in these cells, mimicking in all aspects the natural ligand HGF but displaying a significant higher stability than HGF in culture. This MAb may thus be a valuable substitute for HGF, being more easily available in a biologically active, highly stable, and purified form.
Terahertz local oscillator sources: performance and capabilities (2003)

Frequency multiplier circuits based on planar GaAs Schottky diodes have advanced significantly in the last decade. Useful power in the >1 THz range has now been demonstrated from a complete solid-state chain. This paper will review some of the technologies that have led to this achievement along with a brief look at future challenges.
Serum cytokine levels in heart allograft recipients: correlation with findings on endomyocardial biopsy. (1993)

The ability to detect rejection of human cardiac allografts depends on endomyocardial biopsy diagnosis. Because cytokines are known to mediate allograft rejection events, we chose to examine serum levels of specific cytokines and receptors (interleukin-2 [IL-2], IL-2 receptor [IL-2R], and tumor necrosis factor alpha [TNF-alpha]) and to correlate those levels with findings on endomyocardial biopsy. Sequential sera samples from 23 cardiac allograft recipients were examined for the cytokine levels mentioned, and data correlated with findings on endomyocardial biopsy. Briefly, no statistically correlation of serum cytokine or receptor levels with the stage of allograft rejection was found. When sequential serum cytokine levels were determined in patients experiencing humoral and cellular allograft rejection events, the levels of TNF-alpha appeared to correlate well with endomyocardial biopsy findings. IL-2 and IL-2R levels in two patients who never experienced rejection were elevated on occasion, but TNF-alpha levels were always negative. In summary, measurement of serum cytokine (IL-2, IL-2R) levels in cardiac allograft recipients does not appear to correlate with findings on endomyocardial biopsy; however, elevated levels of TNF-alpha appear to predict more severe humoral allograft rejection episodes and may be helpful in this regard.
Experimental fixed and mobile multibeam satellite communications system (2003)

The authors describe the experimental systems for fixed and mobile satellite communications in the ETS-VI (Engineering Test Satellite VI) program. The objectives of the experiments are space confirmation of the onboard equipment performance necessary for multibeam system implementation and function and performance evaluation of the total system including satellite and earth stations. The multibeam system uses three frequency bands: Ka-band (30/20 GHz), C-band (6/4 GHz), and S-band (2.6/2.5 GHz). A number of new techniques have been applied to enhance the multibeam and satellite switch advantages, including satellite-switch time division multiple access incorporated with demand assigned satellite switch operation, cross-band interconnection associated with cross-band diversity, single-beam/multibeam system interconnection, and band-selective switching. A new multibeam system, called the dynamic channel assigned multibeam satellite system, proposed for the mobile communications system to enhance traffic flexibility, is described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A comparison of Gestalt therapy and Zen Buddhist concepts of awareness (1989)

Etude comparative de deux approches considerant la conscience de soi et du monde comme un concept theorique central
Optimal Color Image Compression Using Localized Color Components Transforms (2008)

Publication in the conference proceedings of EUSIPCO, Lausanne, Switzerland, 2008
The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain. (1994)

The Brn-3a, Brn-3b, and Brn-3c POU family transcription factors are closely related to one another and are members of the group IV subfamily of POU factors. Here we show that despite this close relationship, the factors have different effects on the activity of a target promoter: Brn-3a and Brn-3c stimulate the promoter whereas Brn-3b represses it. Moreover, Brn-3b can antagonize the stimulatory effect of Brn-3a on promoter activity and can also inhibit promoter activation by the Oct-2.1 POU factor. The difference in the transactivation activities of Brn-3a and Brn-3b is dependent upon the C-terminal region containing the POU domain of the two proteins, since exchange of this domain between the two factors converts Brn-3a into a repressor and Brn-3b into an activator.
A weight-lowering device (1947)

A weight-lowering device Get access Leigh Mercer Leigh Mercer Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume 192, Issue 9, 3 May 1947, Page 194, https://doi.org/10.1093/nq/192.9.194c Published: 03 May 1947
Characterization of Genes Encoding Known and Novel Human Mast Cell Tryptases on Chromosome 16p13.3 (1999)

Tryptases are serine proteases implicated in asthma and are very highly expressed in human mast cells. They fall into two groups, alpha and beta. Although several related tryptase mRNAs are known, it is unclear which if any are transcripts of separate haploid genes. The studies described here investigated the nature and number of human tryptases and sought possibly novel members of the family. To this end, two human bacterial artificial chromosome (BAC) clones containing tryptase genes were identified and mapped to chromosome 16p13.3, of which approximately 2.2 megabases are syntenic with the part of mouse chromosome 17 containing tryptase genes mouse mast cell protease (mMCP)-6 and -7. Sequencing and restriction mapping suggest that the BACs may partially overlap. Sequenced BAC genes correspond to three known beta-tryptases (betaI, betaII, and betaIII), an alpha-like gene, and a pair of novel hybrid genes related partly to alpha/beta-tryptases and partly to orthologs of mMCP-7. betaII and betaIII, betaI and alphaII, as well as the two mMCP-7-like genes, may be alleles at single loci; in total, there are at least three nonallelic tryptase genes in the isolated BAC clones. DNA blotting and restriction analysis suggest that the BACs include most members of the immediate tryptase family. Thus, chromosome 16p13.3 harbors a cluster of known and previously undescribed members of the tryptase gene family.
Evaluation of a Novel <sup>18</sup> F-Labeled Positron-Emission Tomography Perfusion Tracer for the Assessment of Myocardial Infarct Size in Rats (2009)

Myocardial (18)F BMS747158-02 PET imaging provides excellent image quality and uptake properties, enabling accurate evaluation of MI size and left ventricular function in rats. It is a promising technique for evaluation of MI size in clinical trials.
Serum transcobalamin in myeloid leukemia. (1971)

Abstract The determination of serum vitamin B 12 concentrations, unsaturated B 12 binding capacity, and total B 12 binding capacity of whole serum and of the separate transcobalamin I and transcobalalamin II fractions has shown that the increased B 12 binding capacity of serum proteins in chronic myeloid leukemia is due mainly to an increase in transcobalamin I. Transcobalamin II is relatively unchanged. Serum B 12 concentrations and unsaturated B 12 binding capacity are only slightly elevated in acute myeloblastic leukemia; total binding capacity of transcobalamin I is within the normal range. The findings observed in acute promyelocytic leukemia are similar to those found in chronic myeloid leukemia. These observations suggest that the excessive amounts of transcobalamin I in chronic myeloid leukemia are produced by proliferating and differentiated myeloid cells beginning at the promyelocytic stage. Transcobalamin I is decreased markedly following the administration of cytotoxic agents.
Malaria, the submerged disease. (1996)

MALARIA is one of the major infectious diseases in the world today despite years of efforts first to eradicate it and subsequently to reduce its impact on mortality and morbidity.Plasmodium falciparum, the most virulent of the four humanPlasmodiumspecies causing malaria, is potentially life-threatening, increasing in prevalence and becoming even more resistant to in-use drugs. The World Health Organization (WHO) estimates that there are 300 million to 500 million people infected with malaria.1The Global Burden of Disease study, used as an input into the World Bank's 1993 World Development Report,2estimated 805 300 deaths due to malaria in sub-Saharan Africa in 1990, compared with 887100 for diarrheal disease, 1 028 800 for all respiratory infections, and 472 000 for measles.3The true impact of malaria on mortality is likely to be underestimated in these figures, since a randomized trial of the use of insecticide-impregnated
Pinpointing Double Bonds in Lipids by Paternò‐Büchi Reactions and Mass Spectrometry (2014)

Abstract The positions of double bonds in lipids play critical roles in their biochemical and biophysical properties. In this study, by coupling Paternò–Büchi (P‐B) reaction with tandem mass spectrometry, we developed a novel method that can achieve confident, fast, and sensitive determination of double bond locations within various types of lipids. The P‐B reaction is facilitated by UV irradiation of a nanoelectrospray plume entraining lipids and acetone. Tandem mass spectrometry of the on‐line reaction products via collision activation leads to the rupture of oxetane rings and the formation of diagnostic ions specific to the double bond location.