gebhart/patrepeval huggingface dataset:
Anion-selective electrode based on oleophilic anion exchange resin membrane (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnion-selective electrode based on oleophilic anion exchange resin membraneToshihiko. Imato, Akinori. Jyo, and Nobuhiko. IshibashiCite this: Anal. Chem. 1980, 52, 12, 1893–1896Publication Date (Print):October 1, 1980Publication History Published online1 May 2002Published inissue 1 October 1980https://pubs.acs.org/doi/10.1021/ac50062a027https://doi.org/10.1021/ac50062a027research-articleACS PublicationsRequest reuse permissionsArticle Views158Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Involvement of Tachykinins and NK<sub>1</sub> Receptor in the Joint Inflammation with Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice (2012)

Rheumatoid arthritis (RA) is a chronic multisystem disease characterized by persistent joint inflammation associated with severe pain. Because RA is an immune-mediated joint disease and because type II collagen is considered an autoantigen, rodent models of arthritis using collagen type II-specific monoclonal antibodies are valuable for studying the pathogenesis of autoimmune arthritis and for evaluating therapeutic strategies. The tachykinin family peptides, substance P (SP) and hemokinin-1 (HK-1), are expressed in the nervous systems and in many peripheral organs and immunocompetent cells and activate tachykinin NK1 receptors with similar affinities. NK1 receptors are involved in the inflammation and hyperalgesia associated with a variety of inflammatory diseases. In the present study, we examined the involvement of SP and HK-1 in the joint inflammation and hyperalgesia in a collagen antibody-induced arthritis (CAIA) model in mice. The messenger RNA expression levels of the TAC1 gene encoding SP and of the TAC4 gene encoding HK-1 were decreased in the dorsal root ganglia and spinal cord at the peak of the inflammatory symptoms in CAIA. Systemic injection of an NK1 receptor antagonist, WIN 51708, significantly inhibited the joint swelling, but not the mechanical allodynia, on day 7 in CAIA mice. The messenger RNA expression levels of TAC1 and TAC4 in the dorsal root ganglia and dorsal spinal cord were unaffected by treatment with WIN 51708. These findings suggest that tachykinins and NK1 receptors play a key role in joint inflammation, rather than in nociceptive sensitization, in CAIA.
Microbial stabilization of antibiotic-containing urine samples by using the FLORA-STAT urine transport system (1991)

The FLORA-STAT Urine Transport System (Wadley Biosciences Corp./Lymphokine Partners Ltd., Dallas, Tex.) was evaluated for its efficacy in maintaining organism count and in effectively blocking the bactericidal action of therapeutic antimicrobial agents in urine samples when the urine samples were held at room temperature. Reconstructions with 53 organism-antimicrobial combinations were performed at 0, 4, 8, and 24 h in which the FLORA-STAT system was compared with two boric acid-based systems (Urine C&S Transport Kit [Becton Dickinson VACUTAINER Systems, Rutherford, N.J.]; Sage Urine Collection Kit for Culture [Sage Products, Inc., Cary, Ill.]) and untreated urine. At 24 h, less than 1-log-unit changes in organism counts were found in 100, 92, and 10% of the urine samples without antimicrobial agents and in 97, 65, and 16% of the urine samples with antimicrobial agents for FLORA-STAT-treated, boric acid-treated, and untreated urine samples, respectively. The FLORA-STAT system was further evaluated by sending split samples prepared from laboratory-inoculated patient urine samples (57 without and 50 with antimicrobial agents) to four commercial laboratories by using their respective transport devices and procedures. Samples were also sent to a local reference laboratory which provided prompt processing. Each laboratory received independently labeled transport devices containing untreated, FLORA-STAT-treated, and preservative-treated (if provided by the commercial laboratory) samples prepared from the same urine specimen of a patient. Average estimated transport times ranged from 13 to 24 h for the commercial laboratories; the transport time was less than 4 h for the local reference laboratory.(ABSTRACT TRUNCATED AT 250 WORDS)
Systematic offset detection and evaluation using hierarchical graph-based sizing and biasing (2007)

A hierarchical graph-based sizing and biasing method of analog circuits has been previously developed. However, conflicts appear in dependency graphs generated by our method due to the large number of degrees of freedom in analog design. Therefore, an enhanced method is presented that automatically detects conflicts and resolves them by inserting systematic offset voltages as additional degrees of freedom into the graph. During graph evaluation, a systematic offset is evaluated as the voltage difference between conflicting nodes, which can be eliminated by transposing it to the inputs of the circuit. As an example, we have successfully applied our method to the sizing of a single-ended two-stage operational amplifier.
[Issue of population quality under economic reform]. (1991)

Under the current economic reform program, various problems about the quality of the population have emerged; dropping out of school is one such problem. In recent years, dropping out of school, has become a prevalent phenomenon. It was estimated that between 1980 and 1987, 40 million primary and middle school students dropped out of school. Drop-outs occurred mostly in primary and middle schools and in rural areas. The reasons for dropping out can be summarized as follows: 1) families could not afford to pay for tuition, 2) students were not able to keep up with school work, and 3) families or students were influenced by other students who had dropped out. In weighing the cost and benefit of attending school, parents would decide whether or not and for how many years to send their children to school. The costs included both direct costs and opportunity costs. Children in urban areas have practically no opportunity costs, while those in rural areas do. Dropping out has been more prevalent among girls than boys. Since girls marry into other families, parents were less willing to invest in their education. On the other hand, the school curriculum gave more emphasis to preparing students for advanced studies than to relaying practical knowledge. Parents did not feel there was any advantage for their children to spend more time in school. Rural economic reform had strengthened the decision-making function of the family in the area of investment. It has also widened the gap between the rich and the poor. For less affluent families, it has become more and more difficult to bear the increasing cost of education. To deal with this problem, the author made several suggestions: 1) persuade parents to continue sending children to school 2) set regulations forbidding the employment of school age children 3) forbid schools to collect unauthorized feeds and establish scholarships to help economically disadvantaged students, 4) develop more vocational schools and change the current curriculum, and 5) develop non-formal education or adult education classes to meet the needs of the rural population.
Unstable genetic determinant of A-factor biosynthesis in streptomycin-producing organisms: cloning and characterization (1984)

We cloned a DNA fragment directing synthesis of A-factor from the total cellular DNA of streptomycin-producing Streptomyces bikiniensis on the plasmid vector pIJ385 . Introduction of the recombinant plasmid ( pAFB1 ) into A-factor-deficient S. bikiniensis and Streptomyces griseus mutants led to A-factor production in the host cells, as a result of which streptomycin production, streptomycin resistance, and spore formation of these mutants were simultaneously restored. The plasmid pAFB1 also complemented both afsA and afsB mutations of Streptomyces coelicolor A3(2). These results indicated that the cloned DNA fragment contained the genetic determinant of A-factor biosynthesis. The cloned fragment, when carried on a multicopy vector plasmid, induced production of a large amount of A-factor in several Streptomyces hosts. In Southern blot DNA/DNA hybridization analyses with a trimmed 5-kilobase fragment containing the intact A-factor determinant as probe, total cellular DNA from A-factor-deficient mutants gave no positive hybridization. The DNA blot experiment also showed a wide distribution of sequences homologous to the S. bikiniensis A-factor determinant among most, but not all, A-factor-producing actinomycetes with a varying extent of homology and the absence of these sequences from most A-factor nonproducers .
Review of low timing jitter mode-locked fiber lasers and applications in dual-comb absolute distance measurement (2018)

Passively mode-locked fiber lasers emit femtosecond pulse trains with excellent short-term stability. The quantum-limited timing jitter of a free running femtosecond erbium-doped fiber laser working at room temperature is considerably below one femtosecond at high Fourier frequency. The ultrashort pulse train with ultralow timing jitter enables absolute time-of-flight measurements based on a dual-comb implementation, which is typically composed of a pair of optical frequency combs generated by femtosecond lasers. Dead-zone-free absolute distance measurement with sub-micrometer precision and kHz update rate has been routinely achieved with a dual-comb configuration, which is promising for a number of precision manufacturing applications, from large step-structure measurements prevalent in microelectronic profilometry to three coordinate measurements in large-scale aerospace manufacturing and shipbuilding. In this paper, we first review the sub-femtosecond precision timing jitter characterization methods and approaches for ultralow timing jitter mode-locked fiber laser design. Then, we provide an overview of the state-of-the-art dual-comb absolute ranging technology in terms of working principles, experimental implementations, and measurement precisions. Finally, we discuss the impact of quantum-limited timing jitter on the dual-comb ranging precision at a high update rate. The route to high-precision dual-comb range finder design based on ultralow jitter femtosecond fiber lasers is proposed.
A fully integrated noise robust strategy for the identification of constitutive laws from digital images (2010)

Abstract Constitutive parameter identification has been greatly improved by the achievement of full‐field measurements. In this context, noise sensitivity has been shown to be of great importance. It is crucial to incorporate noise sensitivity minimization in the design of robust identification procedures. In this paper, we investigate noise sensitivity reduction techniques for constitutive parameter identification based on Finite Element Model Updating. After examining the existing strategies, we propose a single step algorithm based on a mixed optical/mechanical cost function. The key point of this novel procedure is that no boundary conditions are needed. A first example on a real case illustrates the advantages of the proposed methodology in terms of noise sensitivity. A second example shows its capabilities to identify a non‐linear consitutive law. Copyright © 2010 John Wiley & Sons, Ltd.
Hydroxyurea: Mechanism of Action (1963)

Acetohydroxamic acid has been identified, by paper chromatography, in the blood of three patients with chronic myelogenous leukemia on hydroxyurea therapy. This suggests that the drug is hydrolyzed yielding hyroxylamine, which then cleaves thioesters, in particular acetyl-coenzyme A.
Conception et réalisation d'un caloduc plat à rainures en silicium (2003)

"Conception et réalisation d'un caloduc plat à rainures en silicium." La Houille Blanche, 89(4), pp. 62–66Increasing power densities in electronic devices are a direct consequence of their miniaturization and perfonnance improvements. Thus, thermal management has become a main issue. In this article, we propose the use of silicon milliature heat pipes with micro capillary grooves to transport high heat flux. Prototypes were fabricated and tested at a dissipated power up to 30 W/cm2.
An X-ray Study of the Lungs of Workmen in the Asbestos Industry, Covering a Period of ten Years (1939)

DUST inhalation is a subject in which we have been particularly interested for the past ten years. Our approach to this problem has been through the medium of the x-ray. During the past five years, the dust hazard in many industries has become a serious economic factor, for the individual workman as well as for the corporation and insurance company. In some instances the amount of alleged disability among the workmen, from dust, had reached such proportions that insurance companies became insolvent, and the industrial plants were forced to close for lack of compensation insurance protection. During this period, we have had the opportunity of studying the chests of over three thousand workmen exposed to a dust hazard in their regular occupation. This group included various types of dust hazards—mining and manufacturing—and from various parts of this country, east of the Rockies. From this group it has been our privilege to observe with the x-ray the changes in the chest which may result from more or less continuous exposure to various types of dust, such as silica, talc, marble, coal, asbestos, heavy metals, such as iron and brass, and various organic dusts, such as wood fiber. In this rather cursory paper, it is our purpose to record our observations and conclusions based on an x-ray study of one type of dust hazard, namely, asbestos dust. The disease condition resulting from the inhalation of asbestos dust is that form of pneumoconiosis known as asbestosis. We shall comment on this disease, as an economic problem, as it concerns the insurance companies and the industrial accident boards, and also as a disease condition in the individual, its pathology and prognosis as observed by us through the x-ray. In 1928, we began the intensive study of those exposed to the asbestos hazard in one of the large industrial plants in Massachusetts, where brake lining was manufactured. The hazard created was principally asbestos, with less than 30 per cent silica. Dry weaving was first used and then changed to wet weaving. This change was brought about by the fact that in 1928 and 1929 there were numerous cases which showed symptoms, referable to the lungs, characterized by increased difficulty in breathing on exertion, cough, sleeplessness, and loss of weight. Of all the cases we examinedin 1928 and 1929, our records show that in 12 cases x-ray examination revealed changes in the lungs, upon which we based our diagnosis of asbestosis. These 12 were at once put on compensation or given a lump-sum settlement and have been under observation for seven years, throwing considerable light on the natural progress of the disease. From about 1928 to 1933, we routinely examined those cases suspected clinically of asbestosis. By 1933 the insurance premiums had pyramided to 15 per cent of the payroll, and the carriers were rather indifferent to the taking on of this risk.
Thermal decomposition of ammonia. N2H4-an intermediate reaction product (2006)

Abstract The paper reports the thermal decomposition of ammonia under dynamic conditions at 800°C in a quartz reactor. Its purpose is to confirm the homogeneous-heterogeneous degenerated branched chain mechanism established in previous studies, which assume the formation of N2H4 as a molecular intermediate; this paper identifies hydrazine as a product of thermal decomposition using FT-IR and UV-VIS spectroscopies.
The lift and drag forces on a circular cylinder oscillating in a flowing fluid (1964)

Abstract A circular cylinder was placed in a flowing fluid with its axis across the stream. The fluctuating lift and drag forces, and the steady drag force were measured. The results for the stationary cylinder were given in a previous paper (Bishop & Hassan 1964). Here, the results are described and summarized for a cylinder that is made to oscillate transversely in a direction perpendicular to the stream.
Prion-Seeding Activity in Cerebrospinal Fluid of Deer with Chronic Wasting Disease (2013)

Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a uniformly fatal family of neurodegenerative diseases in mammals that includes chronic wasting disease (CWD) of cervids. The early and ante-mortem identification of TSE-infected individuals using conventional western blotting or immunohistochemistry (IHC) has proven difficult, as the levels of infectious prions in readily obtainable samples, including blood and bodily fluids, are typically beyond the limits of detection. The development of amplification-based seeding assays has been instrumental in the detection of low levels of infectious prions in clinical samples. In the present study, we evaluated the cerebrospinal fluid (CSF) of CWD-exposed (n=44) and naïve (n=4) deer (n=48 total) for CWD prions (PrP(d)) using two amplification assays: serial protein misfolding cyclic amplification with polytetrafluoroethylene beads (sPMCAb) and real-time quaking induced conversion (RT-QuIC) employing a truncated Syrian hamster recombinant protein substrate. Samples were evaluated blindly in parallel with appropriate positive and negative controls. Results from amplification assays were compared to one another and to obex immunohistochemistry, and were correlated to available clinical histories including CWD inoculum source (e.g. saliva, blood), genotype, survival period, and duration of clinical signs. We found that both sPMCAb and RT-QuIC were capable of amplifying CWD prions from cervid CSF, and results correlated well with one another. Prion seeding activity in either assay was observed in approximately 50% of deer with PrP(d) detected by IHC in the obex region of the brain. Important predictors of amplification included duration of clinical signs and time of first tonsil biopsy positive results, and ultimately the levels of PrP(d) identified in the obex by IHC. Based on our findings, we expect that both sPMCAb and RT-QuIC may prove to be useful detection assays for the detection of prions in CSF.
New Compounds. 1-Phenylethylidenemalonitrile (1943)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Compounds. 1-PhenylethylidenemalonitrileDavid MowryCite this: J. Am. Chem. Soc. 1943, 65, 5, 991Publication Date (Print):May 1, 1943Publication History Published online13 November 2002Published inissue 1 May 1943https://pubs.acs.org/doi/10.1021/ja01245a601https://doi.org/10.1021/ja01245a601research-articleACS PublicationsRequest reuse permissionsArticle Views110Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Transcriptional Activation of OsDERF1 in OsERF3 and OsAP2-39 Negatively Modulates Ethylene Synthesis and Drought Tolerance in Rice (2011)

The phytohormone ethylene is a key signaling molecule that regulates a variety of developmental processes and stress responses in plants. Transcriptional modulation is a pivotal process controlling ethylene synthesis, which further triggers the expression of stress-related genes and plant adaptation to stresses; however, it is unclear how this process is transcriptionally modulated in rice. In the present research, we report the transcriptional regulation of a novel rice ethylene response factor (ERF) in ethylene synthesis and drought tolerance. Through analysis of transcriptional data, one of the drought-responsive ERF genes, OsDERF1, was identified for its activation in response to drought, ethylene and abscisic acid. Transgenic plants overexpressing OsDERF1 (OE) led to reduced tolerance to drought stress in rice at seedling stage, while knockdown of OsDERF1 (RI) expression conferred enhanced tolerance at seedling and tillering stages. This regulation was supported by negative modulation in osmotic adjustment response. To elucidate the molecular basis of drought tolerance, we identified the target genes of OsDERF1 using the Affymetrix GeneChip, including the activation of cluster stress-related negative regulators such as ERF repressors. Biochemical and molecular approaches showed that OsDERF1 at least directly interacted with the GCC box in the promoters of ERF repressors OsERF3 and OsAP2-39. Further investigations showed that OE seedlings had reduced expression (while RI lines showed enhanced expression) of ethylene synthesis genes, thereby resulting in changes in ethylene production. Moreover, overexpression of OsERF3/OsAP2-39 suppressed ethylene synthesis. In addition, application of ACC recovered the drought-sensitive phenotype in the lines overexpressing OsERF3, showing that ethylene production contributed to drought response in rice. Thus our data reveal that a novel ERF transcriptional cascade modulates drought response through controlling the ethylene synthesis, deepening our understanding of the regulation of ERF proteins in ethylene related drought response.
A software-based minimum-time vergence control scheme for a parallel-axis stereoscopic camera (2004)

We propose a software-based minimum-time vergence control scheme (MTVCS) for a parallel-axis stereoscopic camera (PASC). First, a global horizontal disparity is estimated by using modified binocular energy models and transformed stereoscopic images via Radon Transform with a specified angle parameter. Second, with the estimated global disparity, the actual disparity command is derived through a nonlinear function such that the resulting horizontal disparity is equal to the command exactly with the control in a fastest time interval. Through experimental results, we will show that the proposed MTVCS achieves better tracking and regulating performances than those of the previous scheme.
Facile synthesis of yolk–shell structured Si–C nanocomposites as anodes for lithium-ion batteries (2014)

Yolk-shell structured Si-C nanocomposites are easily synthesized by using a new method based on alkaline etching technology, and exhibit high specific capacity, good cycling stability and rate performance as anodes for lithium-ion batteries.