gebhart/patrepeval huggingface dataset:
A model and equivalent circuit for a superconducting flux flow transistor (1991)

A three-terminal high-frequency active device made of a single film of a high T/sub c/ superconductor that is based on the magnetic control of flux flow is presented. The device is composed of parallel weak links with a nearby magnetic control line. A model has been developed that is based on solving the equation of motion of Abrikosov vortices subject to Lorentz viscous and pinning forces, as well as magnetic surface barriers. The model has been used to predict device transit time (computed from flux velocity) and device I-V curves. The predictions are compared to measured parameters with resulting very good agreement.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Isolation and Mutagenesis of Streptokinase Producing Bacteria (2005)

Of 103 β-haemolytic Streptococci (with haemolytic activity) in total were isolated from different samples of blood and biomass from infected throat, 47 isolates exhibited streptokinase (SK) activity. T3, identified as a new variant of Streptococcus equisimilis, was found to be excellent SK producer in submerged fermentation and was selected for strain improvement studies. This strain was mutagenized by UV and N-methyl-N'-nitro-N-nitroso guanidine (NTG). The isolation of mutants and the SK activity of selected mutants were described. The SK yield of the best UV mutant AUV10 was 120% higher than the wild strain (T3). Also, the SK yield of the best NTG mutant NUV7 was 146% higher than the wild strain (T3). The results indicated that UV and NTG were effective mutagenic agents for strain improvement of S. equisimilis T3 for enhanced SK productivity.
Native American Muses (1981)

musicians, playwrights, and poets founded colonies at Taos and Santa Fe and produced critically acclaimed paintings, sculpture, musical compositions, plays, poetry, and prose.Interestingly, while Anglo aesthetes, dominated the colonies' creative and social life, Indians, most of them from neighboring pueblos, contributed substantially to the colonies' fine arts legacy.From the earliest days of the Taos and Santa Fe colonies, painters had employed Pueblo Indians as studio models.These slender, supple-muscled natives became familiar figures in genre-type paintings that enjoyed sustained popularity.But besides being subjects of art, Indians of northern New Mexico also were creators of works of art.They too were caught up in the art spirit that dominated this region between 1900-1942, and they also contributed to the aesthetic legacy of the Taos and Santa Fe colonies.Indians of the Southwest had a noble ancient tradition for aesthetic expression, confirmed by the abundant evidence archeologists and anthropologists had exposed in the prehistoric ruins of northern New Mexico.During three centuries of Spanish rule, they had endured periodic suppression of lifestyle, religion, and art, but, by cautious sub rosa application, they were able to preserve their muse techniques and tradition.Soon after the United States absorbed this land in 1846, it began to attempt to transform the natives into hybrid Anglo-Americans.Managers of the Americanization program believed that in order to accomplish this it was essential to erase all sign of Indianness.Aboriginal lifestyle, religion, and art were regarded as pagan and thus were forbidden.Indian children, coerced into attending
Glass‐Ceramics (2000)

Abstract Glass‐ceramics are polycrystalline materials formed by the controlled crystallization of glass. Most commercial glass‐ceramic products are formed by highly automated glass‐forming processes and converted to a crystalline product by the proper heat treatment. Glass‐ceramics can also be prepared via powder processing methods in which glass frits are sintered and crystallized. The range of potential glass‐ceramic compositions is therefore extremely broad, requiring only the ability to form a glass and control its crystallization. Glass‐ceramics can provide significant advantages over conventional glass or ceramic materials, by combining the ease and flexibility of forming and inspection of glass with improved and often unique physical properties in the glass‐ceramic. Their physical properties are highly reproducible. Unlike conventional ceramic materials, glass‐ceramics are fully densified with zero porosity. They generally are at least 50% crystalline by volume and often are greater than 90% crystalline. More than $500 million in glass‐ceramic products are sold yearly worldwide. These range from transparent, zero‐expansion materials with excellent optical properties and thermal shock resistance to jade‐like highly crystalline materials with excellent strength and toughness. The highest volume is in cookware and tableware, architectural cladding, and stovetops and stove windows. Glass‐ceramics are also referred to as Pyrocerams, vitrocerams, devitrocerams, sitalls, slagceramics, melt‐formed ceramics, and devitrifying frits.
A high protection voltage dual-gate GaN HEMT clamp for electric vehicle application (2011)

This study presents the development of a novel ESD protection clamp by using dual-gate GaN HEMT technology for electric vehicle application. The proposed novel clamp possesses a low on-state resistance, uniform parasitic capacitance, and 500V trigger voltage for high voltage supply ESD applications. Implementation of the GaN ESD clamp demonstrates a human body mode (HBM) ESD test voltage more than 13kV stress voltage. In addition, the incorporated clamps use a fewer number of diodes than the conventional diode stacks at the trigger terminal, thereby making it size efficient and low effort impedance matching co-design which allow this approach to be an attractive solution for ESD protection.
University of California, Berkeley and Hong Kong Baptist University (1996)

Preview this article: University of California, Berkeley and Hong Kong Baptist University, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/ircl.1.1.24che-1.gif
Assessment of cerebral autoregulation dynamics from simultaneous arterial and venous transcranial Doppler recordings in humans. (1991)

We investigated the validity of transcranial Doppler recordings for the analysis of dynamic responses of cerebral autoregulation. We found no significant differences in percentage changes among maximal (centerline) blood flow velocity, cross-sectional mean blood flow velocity, and signal power-estimated blood flow during 24-mm Hg stepwise changes in arterial blood pressure. We investigated blood flow propagation delays in the cerebral circulation with simultaneous Doppler recordings from the middle cerebral artery and the straight sinus. The time for a stepwise decrease in blood flow to propagate through the cerebral circulation was only 200 msec. Brief (1.37-second) carotid artery compression tests also demonstrated that the volume compliance effects of the cerebral vascular bed were small, only about 2.2% of normal blood flow in 1 second. Furthermore, transients associated with inertial and volume compliance died out after 108 msec. We also investigated the hypothesis that autoregulatory responses are influenced by hyperventilation using the same brief carotid artery compressions. One second after release, the flow index increased by 17% during normocapnia and 36% during hypocapnia. After 5 seconds, the flow index demonstrated a clear oscillatory response during hypocapnia that was not seen during normocapnia. These results suggest that the intact human cerebral circulation in the absence of pharmacological influences does not function as predicted from pial vessel observations in animals.
Glycosylation at Asn91 of H1N1 haemagglutinin affects binding to glycan receptors (2012)

The glycoprotein HA (haemagglutinin) on the surface of influenza A virus plays a central role in recognition and binding to specific host cell-surface glycan receptors and in fusion of viral membrane to the host nuclear membrane during viral replication. Given the abundance of HA on the viral surface, this protein is also the primary target for host innate and adaptive immune responses. Although addition of glycosylation sites on HA are a part of viral evolution to evade the host immune responses, there are specific glycosylation sites that are conserved during most of the evolution of the virus. In the present study, it was demonstrated that one such conserved glycosylation site at Asn(91) in H1N1 HA critically governs the glycan receptor-binding specificity and hence would potentially impinge on the host adaptation of the virus.
A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in <i>Drosophila</i> (2003)

The formation of polyglutamine-containing aggregates and inclusions are hallmarks of pathogenesis in Huntington's disease that can be recapitulated in model systems. Although the contribution of inclusions to pathogenesis is unclear, cell-based assays can be used to screen for chemical compounds that affect aggregation and may provide therapeutic benefit. We have developed inducible PC12 cell-culture models to screen for loss of visible aggregates. To test the validity of this approach, compounds that inhibit aggregation in the PC12 cell-based screen were tested in a Drosophila model of polyglutamine-repeat disease. The disruption of aggregation in PC12 cells strongly correlates with suppression of neuronal degeneration in Drosophila. Thus, the engineered PC12 cells coupled with the Drosophila model provide a rapid and effective method to screen and validate compounds.
Optimizing Color Assignment for Perception of Class Separability in Multiclass Scatterplots (2018)

Appropriate choice of colors significantly aids viewers in understanding the structures in multiclass scatterplots and becomes more important with a growing number of data points and groups. An appropriate color mapping is also an important parameter for the creation of an aesthetically pleasing scatterplot. Currently, users of visualization software routinely rely on color mappings that have been pre-defined by the software. A default color mapping, however, cannot ensure an optimal perceptual separability between groups, and sometimes may even lead to a misinterpretation of the data. In this paper, we present an effective approach for color assignment based on a set of given colors that is designed to optimize the perception of scatterplots. Our approach takes into account the spatial relationships, density, degree of overlap between point clusters, and also the background color. For this purpose, we use a genetic algorithm that is able to efficiently find good color assignments. We implemented an interactive color assignment system with three extensions of the basic method that incorporates top K suggestions, user-defined color subsets, and classes of interest for the optimization. To demonstrate the effectiveness of our assignment technique, we conducted a numerical study and a controlled user study to compare our approach with default color assignments; our findings were verified by two expert studies. The results show that our approach is able to support users in distinguishing cluster numbers faster and more precisely than default assignment methods.
Outlier model using fmax to predict failing devices (2005)

In the fabrication and manufacturing of Very Large Scale Integrated Circuits (VLSI) it is needed to continually seek out new methods to reducing the cost associated with testing and insuring reliability. Using the measured maximum operating frequency of a device compared to the population that the device came from outliers can be identified. Analysis of the characteristics of these outliers predict defective units from other populations by measuring the maximum operating frequency.
Cardiac Workup of Ischemic Stroke (2010)

Stroke is the leading cause of disability in developed countries and the third cause of mortality. Up to 15-30% of ischemic strokes are caused by cardiac sources of emboli being associated with poor prognosis and high index of fatal recurrence. In order to establish an adequate preventive strategy it is crucial to identify the cause of the embolism. After a complete diagnostic workup up to 30% of strokes remain with an undetermined cause, and most of them are attributed to an embolic mechanism suggesting a cardiac origin.There is no consensus in the extent and optimal approach of cardiac workup of ischemic stroke. Clinical features along with brain imaging and the study of the cerebral vessels with ultrasonography or MRI/CT based angiography can identify other causes or lead to think about a possible cardioembolic origin.Atrial fibrillation is the most common cause of cardioembolic stroke. Identification of occult atrial fibrillation is essential. Baseline ECG, serial ECG('s), cardiac monitoring during the first 48 hours, and Holter monitoring have detection rates varying from 4 to 8% each separately. Extended cardiac monitoring with event loop recorders has shown higher rates of detection of paroxysmal atrial fibrillation.Cardiac imaging with echocardiography is necessary to identify structural sources of emboli. There is insufficient data to determine which is the optimal approach. Transthoracic echocardiography has an acceptable diagnostic yield in patients with heart disease but transesophageal echocardiography has a higher diagnostic yield and is necessary if no cardiac sources have been identified in patients with cryptogenic stroke with embolic mechanism.
Phylogenetic origin of the chloroplast and prokaryotic nature of its ribosomal RNA. (1975)

The 16S ribosomal RNA of the Euglena gracilis chloroplast has been characterized in terms of its two-dimensional electrophoretic "fingerprint" (T1 ribonuclease). Results show it to be a typically prokaryotic 16 S rRNA. By the present criterion, different chloroplasts are shown to be related to one another and at least distantly to blue-green algae and perhaps to Bacillaceae. These results argue in favor of an endosymbiont origin of the chloroplast.
Syntactic, Semantic and Sentiment Analysis: The Joint Effect on Automated Essay Evaluation (2019)

Manual grading of essays by humans is time-consuming and likely to be susceptible to inconsistencies and inaccuracies. In recent years, an abundance of research has been done to automate essay evaluation processes, yet little has been done to take into consideration the syntax, semantic coherence and sentiments of the essay's text together. Our proposed system incorporates not just the rule-based grammar and surface level coherence check but also includes the semantic similarity of the sentences. We propose to use Graph-based relationships within the essay's content and polarity of opinion expressions. Semantic similarity is determined between each statement of the essay to form these Graph-based spatial relationships and novel features are obtained from it. Our algorithm uses 23 salient features with high predictive power, which is less than the current systems while considering every aspect to cover the dimensions that a human grader focuses on. Fewer features help us get rid of the redundancies of the data so that the predictions are based on more representative features and are robust to noisy data. The prediction of the scores is done with neural networks using the data released by the ASAP competition held by Kaggle. The resulting agreement between human grader's score and the system's prediction is measured using Quadratic Weighted Kappa (QWK). Our system produces a QWK of 0.793.
Detecting and defeating advanced man-in-the-middle attacks against TLS (2014)

TLS is an essential building block for virtual private networks. A critical aspect for the security of TLS dialogs is authentication and key exchange, usually performed by means of certificates. An insecure key exchange can lead to a man-in-the-middle attack (MITM). Trust in certificates is generally achieved using Public Key Infrastructures (PKIs), which employ trusted certificate authorities (CAs) to establish certificate validity chains.
Schistosome Infections in Humans: Perspectives and Recent Findings (1982)

Approximately 200 million persons are infected with schistosomes. Of those infected, a small proportion develop serious chronic disease, usually after years of intensive exposure and infection. Schistosoma mansoni and Schistosoma japonicum reside in the mesenteric veins and produce liver fibrosis, which results in portal hypertension and bleeding esophageal varices but little hepatocellular dysfunction. Schistosoma haematobium resides primarily in the pelvic veins and produces mass lesions in the bladder and ureters, which lead to hydroureter and hydronephrosis. The intensity of infection is a major factor determining development of disease, but differences in worm strain and host response may also be important. In acute schistosomiasis there is an intense response to the parasite, which is suppressed as the infection becomes chronic. The marked inflammatory response seen in early and acute schistosomiasis becomes less intense and fibrotic lesions predominate. The recent advent of safe, effective, and easily administered chemotherapeutic reagents will aid in the control of schistosomiasis.
Non-destructive evaluation of pork freshness using a portable electronic nose (E-nose) based on a colorimetric sensor array (2014)

This paper investigated the feasibility of rapid non-destructive evaluation of pork freshness using a portable electronic nose (E-nose) based on a colorimetric sensor array.
Increased PHB productivity by high-cell-density fed-batch culture ofAlcaligenes latus, a growth-associated PHB producer (1996)

Alcaligenes latus, a growth-associated PHB producer, was cultivated by a pH-stat modal fed-batch culture technique to attain high PHB productivity. Both sucrose solution and inorganic medium were fed in conjunction with the supply of ammonia solution which serves as a nitrogen source and as a means of pH control. Compositions of the inorganic medium were formulated by elemental analysis of A. latus cell mass. The effect on inoculum size was examined to reduce culture time. High concentrations of cell (142 g/L) and PHB (68.4 g/L) were obtained in a short culture time (18 h) with an inoculum size of 13.7 g/L. The PHB content and the PHB productivity at the end of the fed-batch culture were 50% of dry cell weight and 4.0 g PHB/(L . h), respectively.
Symantec ACT! 4.0 for Windows (1998)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSymantec ACT! 4.0 for Windows†Stephen R. HellerView Author Information NIST, Gaithersburg, Maryland 20899 Cite this: J. Chem. Inf. Comput. Sci. 1998, 38, 4, 772Publication Date (Web):June 30, 1998Publication History Received15 May 1998Published online30 June 1998Published inissue 1 July 1998https://pubs.acs.org/doi/10.1021/ci9802631https://doi.org/10.1021/ci9802631research-articleACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views24Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Biological databases,Interfaces,Software Get e-Alerts
Conformational change of turkey‐gizzard caldesmon induced by specific chemical modification with carbodiimide (1991)

Water soluble 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide was used to internally cross-link carboxyl and lysyl groups of caldesmon. The modification did not involve the two cysteines of the molecule which were previously labelled with N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine. The modified caldesmon exhibited a smaller Stokes radius (4.0 nm instead of 6.3 nm) and its electrophoretic mobility corresponded to an apparent molecular mass of approximately 82 kDa, appreciably lower than that of the native molecule (120 kDa), but more similar to the reported true molecular mass of 86,974 Da of chicken-gizzard caldesmon (Bryan, J., Imai, M., Lee, R., Moore, P., Cook. R. G. & Lin, W. (1989) J. Biol. Chem. 264, 13,873-13,879). Comparative circular dichroism analysis indicated a decrease of the alpha-helix content from 43% to 36% resulting from the chemical modification. The 1H-NMR spectra of the native and modified caldesmon showed that the covalent cross-linking affected mainly the central and N-terminal parts of the molecule. The C-terminal part, rich in aromatic amino acids, was unmodified by the carbodiimide treatment. This was also corroborated by the continued ability of the modified caldesmon to bind to actin and calmodulin, and by the property of the 90-kDa proteolytic N-terminal fragment to give an internally cross-linked species of 60 kDa. Using electron microscopy, the modified protein was shown to have a more compact shape and a reduced capacity to induce tight and long F-actin bundles. These conformational changes were obtained when the carbodiimide reaction was conducted at pH 6.0 and were not observed at pH 8.0. This suggests that local variation of the pH might affect the conformation of caldesmon which changes from an elongated to more compact shape, stabilized by electrostatic interactions. It is proposed that the flexibility of caldesmon might be involved in the regulatory function of this protein in the smooth muscle and might favour tightly packed F-actin bundles or weaker interactions between actin filaments.
Applications of Lgr5-Positive Cochlear Progenitors (LCPs) to the Study of Hair Cell Differentiation (2019)

The mouse cochlea contains approximately 15,000 hair cells. Its dimensions and location, and the small number of hair cells, make mechanistic, developmental and cellular replacement studies difficult. We recently published a protocol to expand and differentiate murine neonatal cochlear progenitor cells into 3D organoids that recapitulate developmental pathways and can generate large numbers of hair cells with intact stereociliary bundles, molecular markers of the native cells and mechanotransduction channel activity, as indicated by FM1-43 uptake. Here, we elaborate on the method and application of these Lgr5-positive cochlear progenitors, termed LCPs, to the study of inner ear development and differentiation. We demonstrate the use of these cells for testing several drug candidates, gene silencing and overexpression, as well as genomic modification using CRISPR/Cas9. We thus establish LCPs as a valuable <i>in vitro</i> tool for the analysis of progenitor cell manipulation and hair cell differentiation.
Observation of particle trajectories in an HGMS single-wire system (1980)

Trajectories of paramagnetic particles were observed experimentally in single-wire HGMS by means of a television system. The observed trajectories were used as a test for the two models of fluid flow, namely potential (inviscid) flow and laminar (viscous) flow. Results of these measurements which were carried out for small Reynolds numbers (0.1 < Re < 0.5) show that the trajectories near a clean collecting wire are described correctly quantitatively by means of the laminar flow model.