gebhart/patrepeval huggingface dataset:
A Study of Sulfur Reactions in Furnace Deposits (1961)

A study was made of absorption of sulfur from synthetic flue gas by coal ash. When fly ash was placed in a temperature gradient like that in a deposit on a boiler tube, maximum absorption was found in the coldest layer. When held at constant temperature, maximum absorption was found at 1100 F. The amount of absorption was highest for fly ash from furnaces in which serious deposit formation was observed. It was also highest for fly ash containing the highest content of sodium and potassium. The sulfur is probably absorbed as mixtures of normal sulfates, pyrosulfates, and such compounds as potassium-ferric trisulfate. A liquid phase of these compounds in contact with tube metal causes corrosion. The maximum sulfur absorption found at 1100 F coincides with a maximum at the same temperature that has been observed for external tube-metal corrosion.
Differential Steroidogenic Gene Expression in the Fetal Adrenal Gland Versus the Testis and Rapid and Dynamic Response of the Fetal Testis to Di(n-butyl) Phthalate1 (2005)

The phthalate ester di(n-butyl) phthalate (DBP) causes feminization of male rats upon in utero exposure by repressing expression of genes required for testicular steroidogenesis. Previous work in our laboratory has shown that repression of gene expression and steroidogenesis in the fetal testis is apparent within a few hours of DBP exposure. The purpose of this study was to determine the precise timing of DBP-associated gene expression changes in the fetal testis using transcriptional profiling and to determine whether DBP exerts similar effects on steroidogenesis in the fetal adrenal. A DBP time-course experiment showed that testicular steroidogenesis was decreased within 1 h of DBP exposure and that this decrease preceded the repressed transcription of Star (steroidogenic acute regulatory protein); Scarb1 (scavenger receptor class B, member 1; also know as Sr-b1); Cyp11a1 (cytochrome P450, family 11, subfamily a, polypeptide 1; also known as P450SCC); and Cyp17a1 (cytochrome P450 family 17, subfamily a, polypeptide 1; also known as Cyp17). Gene expression profiling demonstrated rapid (within 1 to 3 h) and transient induction of immediate early genes in the fetal testis after administration of DBP to the pregnant dam. There was a statistically insignificant decrease in corticosterone production by the fetal adrenal after in utero exposure to DBP from Gestation Day 12 to Gestation Day 19. The extent of steroidogenesis diminution was much less in the adrenal than in the testis (approximately 45% decrease in the adrenal versus 87% decrease in the testis) and expression of genes required for steroidogenesis in the adrenal was unaffected by DBP. Together, these studies demonstrate that DBP initiates a rapid and dynamic change in gene expression in the fetal testis that likely plays a role in the reduction in steroidogenesis that is unique to the fetal testis relative to the steroidogenically active fetal adrenal.
Equally-Spaced Multi-Frequency Laser Emission Generated by Two-Color Stimulated Raman Effect. –Enhancement of Rotational Lines and Suppression of Vibrational Lines– (1991)

A two-color laser beam separated by 587 cm -1 is focused into pressurized hydrogen to generate stimulated Raman emission. By optimizing the hydrogen pressure and the beam focusing condition, only rotational lines are generated in the near-UV region; the vibrational lines are completely suppressed. The rotational lines are further enhanced by using a circularly polarized beam.
High<sup>99m</sup>Tc-DPD myocardial uptake in a patient with apolipoprotein AI-related amyloidotic cardiomyopathy (2012)

Amyloidotic cardiomyopathy is still a widely underdiagnosed condition that usually requires endomyocardial biopsy (EMB) for a definite diagnosis. 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) has proven highly sensitive for detecting amyloidotic cardiomyopathy due to transthyretin-related amyloid deposition. Herein we report the first description of the (99mTc-DPD scintigraphy profile in a patient with suspected amyloidotic cardiomyopathy and a final EMB- and genetically-proven diagnosis of familial apolipoprotein AI amyloidosis due to Leu174Ser variant.
THE MOUSE EAR MODEL OF CUTANEOUS SULFUR MUSTARD INJURY (1997)

AbstractThe mouse ear inflammation model was used to establish simple endpoints of skin injury following cutaneous exposure to sulfur mustard (bis(2- chloroethyl)sulfide, HD). Mouse ear edema and histopathologic response to a single topical application of 5 muL of 8, 16, 32, 64, or 128 mg/mL HD in dichloromethane was evaluated at 12, 18, and 24 h postexposure. Edema response was determined from weighed 8 mm diameter skin punch biopsies taken from the center of exposed and control ears. Key light microscopic histopathologic changes assessed on the inner (exposed side) and outer surfaces (contralateral side) of the exposed ear included epidermal necrosis (EN) and epidermal-dermal separation (subepidermal blister, SEB). HD produced statistically significant (p <. 05) dose- and time-dependent changes in edema and histopathologic features. A comparative evaluation of the endpoint responses from the various challenge doses indicated that a dose of 0.16 mg/ear HD evaluated at 24 h postexposure would be optimal for future studies using this mouse ear vesicant model (MEVM) to screen pharmacological compounds that may protect against HD-induced skin damage.Keywords: : Bis(2-chloroethyl)sulfide Dose Response Edema Histology Inflammation Mouse Ear Skin Sulfur Mustard (HD) Vesication
Analytical investigation of flat silicon micro heat spreaders (2004)

Conventional methods of cooling are not an ideal way to overcome the heat problem in power electronics today. A simple solution would be using micro heat spreader as an integrated part in the silicon substrate. This investigation presents a detailed analysis on maximum heat transfer capabilities of silicon-water cooling devices, flat plate micro heat spreaders. The predictive hydraulic and thermal models were developed to define the heat spreader thermal performances and capillary limitations. Theoretical results of the maximal heat flux that could be transferred agreed reasonably well with the experimental data and the developed model provides a better understanding of the heat transfer capability of micro heat spreaders.
Improving 3D Flow Characteristics in a Multistage LP Turbine by Means of Endwall Contouring and Airfoil Design Modification: Part 2 — Numerical Simulation and Analysis (2002)

Endwall losses contribute significantly to the overall losses in modern turbomachinery, especially when aerodynamic airfoil load and pressure ratios are increased. Hence, reducing the extend and intensity of the secondary flow structures helps to enhance overall efficiency. This work will focus on secondary flow reduction in typical aero engine low pressure turbines. From the large range of viable approaches, a promising combination of axis symmetric endwall contouring and 3D airfoil thickening was chosen. Aerodynamic design, experimental verification and further analysis based on numerical simulation are described in a two part paper. In the second part the implications of the 3D modifications on the flow structure are analyzed by employing a 3D Navier-Stokes simulation based on the experimental data reported in part one. For obtaining reliable flow simulations at typical LP turbine conditions, it is important to apply a 3D Navier-Stokes solver with proven turbulence and transition modeling to the three-stage LP turbine of the Institute of Aeronautical Propulsion at Stuttgart University. Numerical and experimental results exhibit regions, where the modified design leads to a change in flow pattern in accordance with the design intent, as well as regions with an actual increase in loss production. The flow changes in both regions are evaluated and discussed. It is found that a certain local loss increase phenomenon can also be found in other LP turbine rigs. The reasons for this behavior are analyzed by a comparison with data from other turbine rigs and by an additional variation of the 3D design of the first stage of the investigated turbine.
In vitro transformation of the <i>Fusarium</i> mycotoxins deoxynivalenol and zearalenone by the normal gut microflora of pigs (1994)

The biotransformation of the Fusarium mycotoxins deoxynivalenol and zearalenone by the normal bacterial gut flora of pigs was examined in this in vitro study. For that purpose, suspensions of intestinal contents (duodenum, jejunum, caecum, colon, rectum) of porcine origin were incubated anaerobically with deoxynivalenol (DON) or zearalenone (ZEA). DON and ZEA were degraded by the flora of the caudal segments (caecum, colon, rectum) of the gut--particularly the colon content--whereas the microorganisms of the cranial segments (duodenum, jejunum) exhibited no transforming activity. DON was showed to be deepoxidated, ZEA was hydrolyzed to alpha-zearalenol and an unknown metabolite. The transformation of DON was correlated with a loss of cytotoxicity, which could be demonstrated in the MTT(3-[4,5-dimethylthiazol-2yl]-2,5-diphenyltetrazolium++ + bromide)-cell-culture assay using swine kidney cells as target cells. The results of the study presented here correspond with the data found in in vivo studies. On the basis of these findings one could conclude that this in vitro method seems to be well suited to the study of the transformation of mycotoxins by the microflora of the gut. The in vitro study is cheaper than a feeding trial, and the preliminary information on the metabolism of mycotoxins obtained in such studies is helpful in designing feeding trials more clearly. Besides the simple and fast handling, reproducibility and the protection of the animals studied are further advantages of this in vitro method. In connection with the MTT-cell-culture assay, additional information about the cytotoxic potential of the bacterial transformation products can be obtained.
Cytoplasmic domains of GpIbα and GpIbβ regulate 14-3-3ζ binding to GpIb/IX/V (2000)

Shear stress causes the platelet glycoprotein (Gp) Ib/IX/V to bind to von Willebrand factor, resulting in platelet adhesion. GpIb/IX/V also functions to stimulate transmembranous signaling, leading to platelet activation and the expression of a ligand-receptive GpIIb-IIIa complex. The highly conserved cytoplasmic domain of GpIbalpha binds directly to a dimeric 14-3-3 adapter protein zeta isoform. To explore structural determinants of GpIb/IX/V binding to 14-3-3zeta, the authors examined 14-3-3zeta interactions with GpIbalpha and GpIbbeta in heterologous cells and platelets. Truncations of GpIbalpha at amino acid 542 or 594, or deletions of residues 542 through 590, inhibited binding of 14-3-3zeta. Deletion of GpIbalpha from Trp(570) to Ser(590) eliminated 14-3-3zeta binding, and deletion of the sequence from Arg(542)-Trp(570) enhanced binding of 14-3-3zeta to GpIbalpha. All GpIbalpha mutations that eliminated GpIbalpha binding to the GST-14-3-3zeta fusion protein also eliminated GpIbbeta binding to the fusion protein. Forskolin treatment of Chinese hamster ovary cells expressing wild-type GpIbalpha/beta/IX resulted in the phosphorylation of GpIbbeta associated with enhanced binding of GpIbbeta to GST-14-3-3zeta fusion protein and increased 14-3-3zeta coimmunoprecipitated with GpIbalpha. When intact human platelets aggregated in response to 90 dynes/cm(2) shear stress, 14-3-3zeta disassociated from GpIbalpha. Prostacyclin treatment of platelets inhibited shear stress-induced aggregation and the release of 14-3-3zeta from GpIbalpha. These data demonstrate that amino acid residues in the cytoskeletal interaction domains of GpIbalpha regulate 14-3-3zeta binding to GpIbalpha/beta/IX, and suggest that protein kinase A-dependent phosphorylation of GpIbbeta enhances 14-3-3zeta binding to the GpIb/IX/V complex in human platelets. (Blood. 2000;95:551-557)
Public-key ID-based cryptosystem (2002)

It is shown how a chosen-public-key attack can compromise the ID-based cryptosystem of S. Tsujii and T. Itoh (1989), as well as most of the existing public-key cryptosystems. The authors present a scheme which can withstand the chosen-public-key attack, based on the concept of an cryptosystem. The security of the scheme is equivalent to factoring the product of two large primes or solving the discrete logarithm problem. It enciphers data using the receiver's ID directly without the help of a third party.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Self-Management – Potentiale, Probleme, Perspektiven (2004)

ZUSAMMENFASSUNG Gordon Moores Gesetz vom exponentiellen Wachstum der Transistordichte pro Quadrat-Zoll hat seit 1965 die IT-Industrie geprägt. Mit der damit einhergehenden Explosion der Rechnerleistung wurde die Software immer leistungsfähiger, und man ist dazu übergegangen, Rechnersysteme zu vernetzen und Anwendungen zu verteilen. Eine Folge dieser Entwicklungen ist die rapide zunehmende Komplexität der modernen Informationstechnologie. 40 Jahre nach Moores Entdeckung droht eben diese Tatsache, dem bisherigen exponentiellen Wachstum natürliche Grenzen zu setzen. Moderne, vernetzte Rechnersysteme, wie sie in der Industrie weit verbreitet sind, sind schon heute zu komplex als dass sie auf manuellem Wege, d.h., durch menschliche Administratoren, in einem optimalen Betriebszustand gehalten werden können. Die Folgen sind eine unzureichende Ausnutzung vorhandener Ressourcen, wiederkehrende Fehlerzustände und Lücken in der Absicherung gegen mutwillige Angriffe auf die System-Integrität. Dies führt zu erheblichen finanziellen Mehraufwendungen bzw. Verlusten. Ein permanent überfordertes Administrationspersonal, trägt durch eigene Fehler ein Übriges bei. Schenkt man den jüngst aufkeimenden Initiativen von IT-Giganten wie IBM, Microsoft und Sun Glauben, so heißt die Lösung dieser Misere automatisiertes Management . Vernetzte Rechnersysteme sollen sich auf lange Sicht selbst verwalten. Man erhofft sich hiervon ein effektiveres Management und eine Freistellung von Personal, welches sich dann um wichtigere Aufgaben kümmern kann. In diesem Beitrag beleuchten wir den aktuellen Stand und die Perspektiven im Bereich des Self-Managements. Des Weiteren diskutieren wir offene Fragen, welche auf dem Weg zu selbstverwaltenden Systemen zu lösen sind.
Below band-gap optical absorption in GaxIn1−xSb alloys (2005)

The below band-gap optical-absorption characteristics of GaxIn1−xSb alloy system have been reported. The different dependencies of the hole and electron absorption mechanisms on wavelength result in significant changes of the absorption characteristics with alloy composition. In the undoped Ga-rich alloy compositions that are p type in nature (due to residual holes resulting from native defects), the inter-valence-band absorption has been found to be the dominant absorption mechanism. With decreasing Ga (increasing indium) mole fraction, the hole to electron ratio decreases for undoped samples. For such samples, absorption due to electrons becomes significant. With n-type extrinsic doping, intervalley transitions are seen for certain Ga-rich compositions, which also alter the absorption characteristics. The dependencies of various absorption mechanisms as a function of wavelength have been analyzed and discussed in this paper. Based on the theoretical analysis presented in this paper, one can calculate the extrinsic doping level necessary for each alloy composition in order to obtain high optical transparency necessary for infrared optical applications.
Theory and application of triggered vacuum switches (2002)

The triggered vacuum switch (TVS), as a member of the vacuum switch family, has found fast growing applications in recent years. The TVS has many forms: conducting type, turn on and off type and movable electrode TVS, based on different applications. One can define TVS' operation in 3 stages: triggering stage, main electrodes turn on to arcing stage, and post-arc to stead off stage. There are different triggering states. If the initial plasma is produced just on the main cathode, it is called a positive triggering state. And if the trigger is placed on the main anode, it is called a negative triggering state. Formation mechanisms and development of initial plasma are different for both trigger states. Are patterns in TVS will dominate their operations. Most of TVS' are used in the field of pulse power technology, like as a source controller in heavy laser and high power microwave, and in electromagnetic launcher (EML). In this kind of application, the energy storage and pulse formation system need high power closing switches, some times need repeat closing and opening. In some cases, TVS is the best substitution of power electronics or semiconductor elements for its high conduct power and high voltage withstanding.
Muscle electrotransfer as a tool for studying muscle fiber-specific and nerve-dependent activity of promoters (2003)

Muscle electrotransfer has recently become a promising tool for efficient delivery of plasmids and transgene expression in skeletal muscle. This technology has been mainly applied to use of muscle as a bioreactor for production of therapeutic proteins. However, it remains to be determined whether muscle electrotransfer may also be accurately used as an alternative tool to transgenesis for studying aspects of muscle-specific gene control that must be explored in fully mature muscle fibers in vivo, such as fiber specificity and nerve dependence. It was also not known to what extent the initial electrical stimulations alter muscle physiology and gene expression. Therefore, optimized conditions of skeletal muscle electroporation were first tested for their effects on muscles of transgenic mice harboring a pM310-CAT transgene in which the CAT reporter gene was under control of the fast IIB fiber-specific and nerve-dependent aldolase A pM promoter. Surprisingly, electrostimulation led to a drastic but transient shutdown of pM310-CAT transgene expression concomitant with very transient activation of MyoD and, mostly, with activation of myogenin, suggesting profound alterations in transcriptional status of the electroporated muscle. Return to a normal transcriptional state was observed 7-10 days after electroporation. Therefore, we investigated whether a reporter construct placed under control of pM could exhibit fiber-specific expression 10 days after electrotransfer in either fast tibialis anterior or slow soleus muscle. We show that not only fiber specificity, but also nerve dependence, of a pM-driven construct can be reproduced. However, after electrotransfer, pM displayed a less tight control than previously observed for the same promoter when integrated in a chromatin context.
Prefrontal Activation Associated with Social Attachment: Facial-Emotion Recognition in Mothers and Infants (2008)

Attachment between mothers and infants is the most primitive and primary form of human social relationship. Many reports have suggested that the orbitofrontal cortex (OFC) plays a significant role in this attachment; however, only a select few provide experimental neurophysiological evidence. In the present study, to determine the neural substrates underlying the social and emotional attachment between mothers and infants, we measured their prefrontal activation by using near-infrared spectroscopy. We used movie stimuli that could robustly induce a positive affect, and the results for viewing own versus unfamiliar infants showed that own-infant viewing elicited increased activations around the anterior part of the orbitofrontal cortex (OFC) in the mothers. Their response magnitude in that area was also correlated with the behavioral rating of the pleasant mood of infants. Furthermore, our study revealed that the infants' prefrontal activation around the anterior OFC is specific to viewing their mothers' smile. These results suggest the OFC's role in regulating and encoding the affect in attachment system and also show that infants share similar neuronal functions with mothers, associated with their bonds at 1 year of age. We further discussed infants' prefrontal activations and their implications for the development of the social brain network.
Enhanced security and authentication mechanism in cloud transactions using HMAC (2014)

In a cloud environment, which deploys transactional database systems, the entities participating in the system provides proofs of authorization to the cloud server. The proofs may be any valid data given by the end user participating in a transaction being evaluated by a transaction manager for authorization purposes. There is a relaxed consistency model underlying the cloud services due to its elasticity. When the transaction databases are associated with distributed environment, there is a problem of inconsistency arising in the course of a transaction. First, the system meets many policy inconsistencies during the policy update process. Second, some factors which are external can cause the user credential inconsistencies during the transaction. To overcome these inconsistencies present in a cloud transaction the concept of trusted transaction is proposed which do not violate any policy or credential inconsistencies. The more general term can be given by using safe transactions which identifies the trusted transactions which conform to the basic properties of distributed storage systems. In this paper, we propose a method to enhance the security and authenticity of transactions performed through cloud environment. Study on, how safe and trusted transactions be performed by applying HMAC algorithm with associated policies is carriedout.
Interactive report A comparison of the expression and properties of Apaf-1 and (2000)

Apaf-1 is a mammalian homolog of CED-4 that regulates cell death by participating in a ternary complex with cytochrome c, and procaspase-9. In the case of CED-4, two splice variants exist. The smaller (CED-4S) is proapoptotic while the larger (CED-4L) contains a short in-frame insert and is anti-apoptotic. We cloned a murine variant of apaf-1, termed apaf-1L, which contains an eleven amino acid insert similar to a recently described human apaf-1L clone. apaf-1 and apaf-1L have similar distributions in adult and fetal tissues, although apaf-1L transcripts are more abundant. Apaf-1L, undergoes homomerization and heteromerization with Apaf-1 in yeast. Apaf-1L also binds to caspase-9 and a dominant-negative isoform of caspase-9. Unlike CED-4, neither Apaf-1 variant was lethal in yeast. However, both Apaf-1 and Apaf-1L elicit cell death when cotransfected with caspase-9 into 293 EBNA cells. Although Apaf-1L was more potent than Apaf-1, their biological properties were qualitatively similar. © 2000 Elsevier Science B.V. All rights reserved. Theme: Development and regeneration Topic: Neuronal death
Stimulated Emission from Organic Dye Solutions Pumped by a Small Coaxial N_2 Laser (1970)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. C. Clark and T. J. Davies, "Stimulated Emission from Organic Dye Solutions Pumped by a Small Coaxial N2 Laser," Appl. Opt. 9, 1725-1726 (1970) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Measurement of centerline segregation in steel slabs (2006)

Segregation in steel cast products is an internal defect that can be very harmful when slabs are rolled to thick plate. Several tools of segregation measurement have been developed in previous works. In this work it is presented an automatic tool based on image processing which allows both automatic measurement of segregation and automatic detection and measurement of cracks in steel slabs. This tool has been called MESEG