gebhart/patrepeval huggingface dataset:
Larvicidal activity of Bacillus thuringiensis subsp. israelensis in the dipteran Haematobia irritans (1984)

A strain of Bacillus thuringiensis subsp. israelensis was found to be larvicidal to horn flies, Haematobia irritans (L. [Diptera:Muscidae]). The toxic activity was particulate, appeared during sporulation, and could be prevented by the addition of streptomycin before sporulation. Density gradient centrifugation in Renografin was used to separate endospores, crystals, and low-density particulate matter (fraction 3) from sporulated preparations. Larvicidal activity was restricted to purified crystals and fraction 3, indicating that delta-endotoxin of B. thuringiensis subsp. israelensis was active against horn fly larvae. Purified crystals produced mortality during larval feeding stages, but not pupal stages. Fraction 3 produced significant mortality during both larval and pupal stages. The mortality data indicated the presence of at least two dipteran-active toxins.
Diffuser radiation patterns over a large dynamic range 1: Strong diffusers (1988)

Theoretical computations are presented for the far-zone radiation patterns from strong diffusers having a normally distributed height profile and different autocorrelation functions for the surface height. Diffusers having two scales of roughness are also analyzed. Data are presented from ground-glass and acid-etched-glass diffusers using a scatterometer that permits measurements over an entire hemisphere with a dynamic range of 6-8 orders of magnitude. For the ground glass, excellent agreement is obtained using an autocorrelation function that is conical for small spatial offsets; this is consistent with our physical expectation based on the need for a rapid fall-off in surface correlation, due to the jagged nature of the surface relief. For the acid-etched case, excellent agreement is found using an autocorrelation function that is paraboloidal for small spatial offsets. Remote sensing of surface roughness and surface correlation are seen to be practical and accurate.
Experimental performance investigation of uniform and non-uniform cooling techniques for photovoltaic systems (2015)

Uniform cooling of photovoltaic (PV) panels is one of the key parameters to optimize the cell efficiency. Temperature non-uniformity on the surface of PV panel has a major affect on the global performance of PV systems and directly increases cell resistance which leads to a drop in the output of the system. In this paper, an experimental performance investigation has been carried out for non-uniform and uniform cooling techniques for PV panels subjected to the climate of Saudi Arabia. A uniform cooling technique for PV panels based on impingement cooling device is proposed to eliminate non-uniform heat transfer across the surface of the PV panel and its performance is compared with a conventional rectangular channel heat exchanger(RHX).The PV string's overall performance was found to be sensitive with the thermal characteristics of the system. Measurements showed cell temperature as high as 83°C for PV string without cooling. By employing impingement cooling, cell temperature was reduced to 37.1°C whereas conventional heat exchanger reduced it to 47.4°C. Conversion efficiency was enhanced by 98.4 % for impingement cooling and 60.6 % for heat exchanger cooling. Results reveal that impingement cooling has not only increased the electrical power output and conversion efficiency but has reduced the cell temperature while keeping it uniform for each cell.
Intrauterine Devices and Pelvic Inflammatory Disease (1984)

There is convincing clinical evidence that PID is more common in IUD users than in users of other contraceptive methods. There appears to be a smaller but significant increase when IUDs are compared with sexually active noncontraceptive users. However, the incidence of PID severe enough to warrant hospitalization is only of the order of 1 to 2 per 1,000 women per year. The question which remains is whether beyond this low figure of moderate and severe disease there is a much higher incidence of subclinical PID which may result in complications for IUD users. Development of a marker such as C-Reactive protein or the split complement component C3d to detect mild PID would prove invaluable in the elucidation of several crucial problems in the clinical management of women using IUDs.
Distributed energy saving management in multi-layer 4G/5G ultra-dense networks (2018)

Energy consumption in mobile networks rises with increase in cell density. This trend will only continue in the future multi-layer 5G-related Ultra-Dense Networks (UDN) that are characterized by high number and density of cells in multiple radio technologies each in one or more layers. Several Energy Saving Management (ESM) solutions have been published, but none adequately address the UDN scenario. UDNs require a distributed solution that allows each cell to individually decide when to deactivate or reactivate itself while considering the amount of network-wide traffic and the need to minimize signaling between the cells. This paper describes such a solution and its implementation, as well as a case study in a typical 5G UDN scenario with multiple cell layers of different cell sizes.
Low Temperature Dopant Activation for Integrated Electronics Applications (2006)

A major area of research for integrated electronic systems is the development of systems on glass or plastic. These alternative substrate materials impose significant constraints on electronic device fabrication, including limitations on chemical and thermal processes. This work presents an investigation on the activation of ion-implanted dopants without using the high temperature processes of conventional CMOS. The annealing temperature applied was 600degC, which could potentially enable integrated microelectronics on high-quality glass. Additional factors studied included the annealing technique (furnace or rapid thermal processing), and the use of pre-amorphization implants. Ion-implant modeling along with SIMS and SRP data was used to develop a comprehensive understanding of the experimental results. The performance of transistors fabricated with low-temperature constraints on both bulk silicon and thin- film SOI was presented.
Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities (2009)

STATs are constitutively activated in several malignancies. In primary mediastinal large B-cell lymphoma and Hodgkin lymphoma (HL), inactivating mutations in SOCS1, an inhibitor of JAK/STAT signaling, contribute to deregulated STAT activity. Based on indications that the SOCS1 mutations are caused by the B cell-specific somatic hypermutation (SHM) process, we analyzed B-cell non-HL and normal B cells for mutations in SOCS1. One-fourth of diffuse large B-cell lymphoma and follicular lymphomas carried SOCS1 mutations, which were preferentially targeted to SHM hotspot motifs and frequently obviously inactivating. Rare mutations were observed in Burkitt lymphoma, plasmacytoma, and mantle cell lymphoma but not in tumors of a non-B-cell origin. Mutations in single-sorted germinal center B cells were infrequent relative to other genes mutated as byproducts of normal SHM, indicating that SOCS1 inactivation in primary mediastinal large B-cell lymphoma, HL, diffuse large B-cell lymphoma, and follicular lymphoma is frequently the result of aberrant SHM.
Matricellular Proteins: A Sticky Affair with Cancers (2012)

The multistep process of metastasis is a major hallmark of cancer progression involving the cointeraction and coevolution of the tumor and its microenvironment. In the tumor microenvironment, tumor cells and the surrounding stromal cells aberrantly secrete matricellular proteins, which are a family of nonstructural proteins in the extracellular matrix (ECM) that exert regulatory roles via a variety of molecular mechanisms. Matricellular proteins provide signals that support tumorigenic activities characteristic of the metastastic cascade such as epithelial-to-mesenchymal (EMT) transition, angiogenesis, tumor cell motility, proliferation, invasion, evasion from immune surveillance, and survival of anoikis. Herein, we review the current understanding of the following matricellular proteins and highlight their pivotal and multifacted roles in metastatic progression: angiopoietin-like protein 4 (ANGPTL4), CCN family members cysteine-rich angiogenic inducer 61 (Cyr61/CCN1) and CCN6, osteopontin (OPN), secreted protein acidic and rich in cysteine (SPARC), tenascin C (TNC), and thrombospondin-1 and -2 (TSP1, TSP2). Insights into the signaling mechanisms resulting from the interaction of these matricellular proteins and their respective molecular partner(s), as well as their subsequent contribution to tumor metastasis, are discussed. In addition, emerging evidences of their promising potential as therapeutic options and/or targets in the treatment of cancer are also highlighted.
Proton conduction and bafilomycin binding by the V0 domain of the coated vesicle V-ATPase. (1994)

We have previously demonstrated that the V0 domain of the coated vesicle V-ATPase, a 250-kDa integral complex, does not form a functional proton channel (Zhang, J., Myers, M., and Forgac, M. (1992) J. Biol. Chem. 267, 9773-9778). In the present study we describe dissociation of the V0 complex and separation of the V0 subunits by gel filtration. Dicyclohexylcarbodiimide-inhibitable passive proton conductance of reconstituted vesicles containing reassembled V0 subunits was measured in response to a K+/valinomycin-generated membrane potential. We observed that reconstituted vesicles containing the 17/19-kDa subunits carried out passive proton transport, with the addition of the 38- and 100-kDa subunits increasing proton conductance. Reconstituted vesicles containing the 38- and/or 100-kDa subunits showed no proton transport. Partial separation of the 17- and 19-kDa subunits revealed that the 17-kDa subunit alone carried out proton transport, with increased conductance on the addition of the 19-kDa subunit. These results indicate that the V0 domain possesses the information necessary to form a dicyclohexylcarbodiimide-inhibitable passive proton channel. Bafilomycin binding by native and reassembled V0 complexes was also measured by their ability to protect V-ATPase activity against bafilomycin inhibition. The native V0 domain, the isolated 100-kDa subunit and the 100/38-kDa subunits were able to protect against inhibition by bafilomycin, suggesting that the binding site for bafilomycin resides on the 100-kDa subunit.
Bottom-up soft-lithographic fabrication of three-dimensional multilayer polymer integrated optical microdevices (2004)

We develop a method to efficiently fabricate three-dimensional multilayer polymer microchips for integrated optical applications. This method uses soft lithography to mold the core structures on top of the cladding layers. By repeating the process, a three-dimensional multilayer integrated optical microdevice, which consists of several layers of individual planar optical devices, is fabricated. We demonstrate a dual-layer microring resonator optical filter device where the devices in the different layers show essentially identical transmission responses.
2005 Immunosuppressive Strategies in Kidney Transplantation: Which Role for the Calcineurin Inhibitors? (2005)

The calcineurin inhibitors (CNIs) cyclosporine and tacrolimus have been the cornerstones of immunosuppressive strategies in clinical transplantation. Currently, regimens that are most widely used for induction and maintenance therapy include CNIs. However, many clinical trials aiming at reducing or eliminating CNIs have been performed in recent years. Here, we review and discuss current and future immunosuppressive strategies with a special emphasis on the role of CNIs, in the light of recent studies in the field of kidney transplantation. In the current era, CNIs still play an important role.
Zone-electrophoretic pattern of proteins in the cystic fluid of ovarian tumors (1972)

Fifty-one ovarian cystomas and cystic ovarian tumors were analyzed by vertical disc-electrophoresis for their protein content and the pattern of their protein distribution. In order to find typical electrophoretic patterns for the different kinds of cystomas, the protein fractions detected were correlated with seven histologically distinct groups. The results were compared with normal human serum pherograms.
The Preparation and Properties of some Synthetic Inorganic Anion Exchangers (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation and Properties of some Synthetic Inorganic Anion ExchangersE. J. Duwell and J. W. ShepardCite this: J. Phys. Chem. 1959, 63, 12, 2044–2047Publication Date (Print):December 1, 1959Publication History Published online1 May 2002Published inissue 1 December 1959https://pubs.acs.org/doi/10.1021/j150582a016https://doi.org/10.1021/j150582a016research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Calcitonin Resistance: Clinical and Immunologic Studies in Subjects with Paget's Disease of Bone Treated with Porcine and Salmon Calcitonins (1972)

15 patients with Paget's bone disease were treated with varying schedules of porcine (3.8-157.5 MRCU/kg per wk) and/or salmon (1.5-210 MRCU/kg per wk) calcitonins over periods ranging from 4 to 24 months. All of the subjects experienced a striking decrease in serum alkaline phosphatase during the first 4 months of treatment. In six patients, however, resistance to these peptides was suggested by a subsequent elevation of alkaline phosphatase activity in spite of continued and augmented hormone administration. These rebounds in alkaline phosphatase levels correlated with the appearance of calcitonin-binding substances and neutralizing material in serum. Incubations of calcitonins-(125)I and sera from these six subjects resulted in the association of radioactivity with material whose behavior on chromatoelectrophoresis (6/6), sucrose density ultracentrifugation and immunoelectrophoresis (one subject) was identical with that of 7S immunoglobulin. Specific, reversible in vitro binding of salmon calcitonins-(125)I was observed in sera obtained from these patients 5 to 12 months after initiation of salmon calcitonin therapy. All six of these subjects' sera acquired the capacity to neutralize salmon calcitonin's hypocalcemic effect in rat bioassay. Neutralization titers correlated with maximal binding capacities, which ranged from 0.042 to 6.6 mg/liter of serum. Competitive displacement of calcitonins-(125)I from the sera of one patient treated with both porcine and salmon calcitonin indicated separate populations of antibodies to these hormones. In spite of return of disease activity comparable to baseline levels, 3/5 resistant subjects treated with salmon calcitonin failed to develop hypocalcemia after injection of 300-1000 MRCU of salmon calcitonin, but two of these patients developed hypocalcemia in response to the porcine hormone. The disappearance of total radioactivity from the circulation after intravenous administration of salmon calcitonin-(125)I was retarded and the amount of serum radioactivity precipitable in 50% (NH(4))(2)SO(4) greater in 3/3 resistant patients compared to control subjects. These observations on the incidence of significant titers of neutralizing antibodies to salmon (40%) and porcine (66%) calcitonins during their chronic (> 4 months) administration to man clearly indicate that an appraisal of this possibility be included in studies involving protracted use of these hormones.
TweetGlue: Leveraging a crowd tracking infrastructure for mobile social augmented reality (2015)

In this paper, we design a mobile augmented reality (AR) system called TweetGlue, which overlays text messages (i.e., tweets) that are posted to a local social networking service onto live view images from cameras in mobile/wearable devices. By displaying the tweets at the current positions of the users who posted them, it supports social interaction between the users. Accurate pose tracking of mobile devices is an essential building block of such mobile AR applications. While visual features that are extracted from scenes are commonly used for vision-based pose estimation, it would not be suitable for such a mobile social AR application because the features may be often occluded by human bodies nearby. To cope with the problem, we leverage an external pedestrian tracking system using a small number of laser-based distance measurement sensors (i.e., LRS sensors) to utilize the surrounding human bodies as virtual markers for pose estimation. The mobile devices periodically analyze images from the embedded camera sensor to estimate relative positions of pedestrians in the images. By matching the estimated relative positions with accurate human location measurements by the LRS sensors, the system robustly identifies location and horizontal orientation of the devices. Through simulation experiments, we show that the TweetGlue system can accurately identify pose of mobile devices in 83% of the simulated scenarios.
A microfluidic shear device that accommodates parallel high and low stress zones within the same culturing chamber (2014)

Fluid shear stress (FSS) plays a critical role in regulating endothelium function and maintaining vascular homeostasis. Current microfluidic devices for studying FSS effects on cells either separate high shear stress zone and low shear stress zone into different culturing chambers, or arranging the zones serially along the flow direction, which complicates subsequent data interpretation. In this paper, we report a diamond shaped microfluidic shear device where the high shear stress zone and the low shear stress zone are arranged in parallel within one culturing chamber. Since the zones with different shear stress magnitudes are aligned normal to the flow direction, the cells in one stress group are not substantially affected by the flow-induced cytokine/chemokine releases by cells in the other group. Cell loading experiments using human umbilical vein endothelial cells show that the device is able to reveal stress magnitude-dependent and loading duration-dependent cell responses. The co-existence of shear stress zones with varied magnitudes within the same culturing chamber not only ensures that all the cells are subject to the identical culturing conditions, but also allows the resemblance of the differential shear stress pattern in natural arterial conditions. The device is expected to provide a new solution for studying the effects of heterogeneous hemodynamic patterns in the onset and progression of various vascular diseases.
Bis-naphthalimides bridged by electron acceptors: optical and self-assembly characteristics (2016)

The self-assembly of small organic molecules into molecular stacks plays a vital role in the construction of stable supramolecular structures.
Anti-infrared/ultraviolet property of fullerene-containing polyacrylate film (2004)

High-optical quality polyacrylate films containing a small load of C60 were prepared by blending the soluble polyacrylate with the fullerene C60 derivative poly-[2-(acrylamido)-2-methylpropane sulfonic acid] (PAMPS)-C60. TEM was used to observe the morphological structure of the fullerene-containing polyacrylate solution. The anti-infrared/ultraviolet property was characterised by UV–VIS and FTIR in the wavelength range of 190–5000 nm. Experimental results demonstrated an improved anti-IR/UV property of polyacrylate as well as good diaphaneity. In the visible spectrum, its transmittance was greater than 80%. In the UV region, the transmittance decreased to 10% (<300 nm). Meanwhile, the transmittance was 55·7% in the near IR wave range (4000–14000 cm−1) and 31% in the middle IR wave range (2000–4000 cm−1), respectively. This new nanocomposite material has great potential to serve as an anti-IR/UV thin coating to implement heat insulation in many applications.
Relating Body Size to the Rate of Home Range Use in Mammals (1988)

The area occupied or traversed by an aimal is a function of the time period considered, but few empirical estimates of the temporal component of home range use are available. We used a statistic called the "time to independence" to make an ecollogically meaningful estimate of the amount of time required for an individual to traverse its home range. Data from 23 species of terrestrial mammals indicated the existence of a size—dependent time scale governing the rate of home range use. Foraging mode influenced the rate of home range use; central place foragers traversed their home ranges approximately five times as rapidly as comparably sized noncentral place foragers. Numerous physiological measures of time are related to body mass raised to the 1/4 power. Our results suggest that the time scale governing the rate of space use by mammals is related similarly to body mass. This relationship permits a more critical examination of factors throught to influence home range size, including habitat prodictivity and social organization.
An <i>In Vivo</i> Technique for the Study of Phloem Unloading in Seed Coats of Developing Soybean Seeds (1983)

A technique has been developed which permits mechanistic studies of phloem unloading in developing seeds of soybean (Glycine max cv Clark) and other legumes. An opening is cut in the pod wall and the embryo surgically removed from the seedcoat without diminishing the capacity of that tissue for assimilate import, phloem unloading, or efflux. The sites of phloem unloading were accessible via the seedcoat apoplast and were challenged with inhibitors, solutes, buffers, etc., to characterize the unloading process.Unloading is stimulated by divalent metal chelators and diethylstilbestrol, and inhibited by metabolic uncouplers and sulfhydryl group modifiers. Solutes released from the seed coat had a carbon/nitrogen ratio of 31 milligrams carbon per milligram nitrogen; sucrose represented 90% of the carbon present and various nitrogenous solutes contributed the remaining 10%. Unloading could be maintained for up 8 hours at rates of 0.5 to 1.0 micromoles per hour, providing a valid, convenient in vivo technique for studies of phloem unloading and seed growth mechanisms.
Performance of Modified Decision-Directed Polarization Control/Demultiplex Algorithm in Coherent QAM Receiver (2010)

A modified decision-directed polarization control and demultiplex algorithm for coherent receivers is evaluated for QAM schemes up to order 256, and compared against the constant-modulus algorithm adapted for QAM and differential phase compensation.