gebhart/patrepeval huggingface dataset:
Disseminated Microsporidiosis Due To Septata intestinalis In Patients With AIDS: Clinical Features And Response To Albendazole Therapy (1995)

Five patients with AIDS had disseminated infection due to Septata intestinalis, a recently described organism. S. intestinalis infection was suspected after detection of spores in stools and urine and confirmed by transmission electron microscopy of duodenal biopsies or of cell culture of urine sediment. Clinical features included chronic diarrhea that was usually associated with fever, cholangitis, sinusitis, bronchitis, or mild bilateral conjunctivitis. Mean CD4 cell count was 22/microL. Patients treated with albendazole (400 mg orally twice a day) for a mean of 19 days had a dramatic and rapid clinical response to therapy. Significant reduction of parasite shedding was also observed during therapy; S. intestinalis was cleared from stools of all patients and from urine of 3. In 2 patients, however, microsporidian spores were detected in feces during follow-up and mild diarrhea recurred. Therefore, albendazole seems to have a significant but transient effect in treatment of S. intestinalis infection.
Rapid phlorotannin induction and relaxation in five Washington kelps (1998)

Wounding of both terrestrial and marine plants is known to induce chemical responses in the plants; the induced compounds may defend against herbivory or act in wound-healing processes. We demonstrate here, for the first time, induction of phlorotannins in kelps (Phaeophyta, Laminariales). an important and widespread group of marine benthic algae. The rapid response of kelps to mechanical wounding contrasts with previously published work on other marine algae, where response has been slower. In 4 of the 5 species tested, induction (increases of approximately 30 to 9036 of original levels) occurred very rapidly, within 1 to 3 d of wounding, although the magnitude and duration of the induction varied among species and tissue types. Many induced responses persisted for 5 to 7 d and then relaxed. Relaxation times are a critical component in the hypothesized cost-effectiveness of induced versus constitutive defenses, and this is one of the first attempts to measure relaxation times of chemlcal defenses in marine algae. The temporal persistence of the response suggests an anti-herb~vory rather than a wound-healing function for induction of phlorotannins, although this needs further testing KEY MiORDS Kelp phlorotannins .
Application of average Hamiltonian theory to the NMR of solids (1982)

The question of the validity of the average Hamiltonian theory is discussed. This is derived from consideration of the Floquet theorem for periodic systems. A perturbation scheme is developed and shown to give an average Hamiltonian equivalent to that obtained from the Magnus expansion. The convergence condition is shown to depend on the existence of resonances. These results are applied to a discussion of pulse spin-locking experiments.
Simultaneous design in both magnitude and group-delay of IIR and FIR filters based on multiple criterion optimization (1984)

This work considers the simultaneous design in both magnitude and group-delay of digital transfer functions on the basis of multiple criterion optimization. Both causal IIR filters and nonlinear phase FIR filters are studied. Examples of the optimal tradeoff filters, both FIR filters and IIR filters, are presented and their characteristics are analyzed.
Simple analytical embedded-atom-potential model including a long-range force for fcc metals and their alloys (1996)

A simple analytical embedded-atom method (EAM) model is developed. The model includes a long-range force. In this model, the electron-density function is taken as a decreasing exponential function, the two-body potential is defined as a function like a form given by Rose et al. [Phys. Rev. B 33, 7983 (1986)], and the embedding energy is assumed to be an universal form recently suggested by Banerjea and Smith. The embedding energy has a positive curvature. The model is applied to seven fcc metals (Al, Ag, Au, Cu, Ni, Pd, and Pt) and their binary alloys. All the considered properties, whether for pure metal systems or for alloy systems, are predicted to be satisfactory at least qualitatively. The model resolves the problems of Johnson's model for predicting the properties of the alloys involving metal Pd. However, more importantly, (i) by investigating the structure stability of seven fcc metals using the present model, we found that the stability energy is dominated by both the embedding energy and the pair potential for fcc-bcc stability while the pair potential dominates and is underestimated for fcc-hcp stability; and (ii) we find that the predicted total energy as a function of lattice parameter is in good agreement with the equation of state of Rose et al. for all seven fcc metals, and that this agreement is closely related to the electron density, i.e., the lower the contribution from atoms of the second-nearest neighbor to host density, the better the agreement becomes. We conclude the following: (i) for an EAM, where angle force is not considered, the long-range force is necessary for a prediction of the structure stability; or (ii) the dependence of the electron density on angle should be considered so as to improve the structure-stability energy. The conclusions are valid for all EAM models where an angle force is not considered. \textcopyright{} 1996 The American Physical Society.
Properties of slotted dielectric interfaces (1959)

A theoretical analysis of slotted dielectric interfaces based on an application of the Rayleigh-Ritz method is presented. Formulas for calculating the equivalent circuit parameters are derived for arbitrary polarization and angles of incidence. Numerical results are given which show that the slotted dielectric interface behaves essentially as a homogeneous anisotropic dielectric interface. Formulas and numerical values of the equivalent dielectric constants are also given.
Wake-up Treatments for Improving Oviposition and Colony Development of the Bumblebees Bombus ignitus and B. terrestris (2010)

Bumblebees are widely used to pollinate crops in greenhouses and fields. Here, we investigated whether different wake-up treatments during a short period of 1~3 days just before indoor rearing has any effects on oviposition and colony development of -treated Bombus ignitus queens and artificially hibernated B. terrestris queens The wake-up regimes were defined as 16L for 1 day (16L-1), 16 L per day for 3 days (16L-3), 24L for 1 day (24L-1), or 24D for 1 day (24D-1). Among these wake-up treatments, the oviposition rate and preoviposition period of B. ignitus queens reared at 24L-1 were 16.7~25.1% higher and 1.0~3.5 days shorter than other wake-up treatments. B. terrestris queens reared at 24L-1 also showed the best results for egg-laying characteristics, which were 8.9~18.8% higher for oviposition and 0.6~3.5 days shorter for preovipostion period than other wake-up treatments. Furthermore, B. terrestris queens reared at 24L-1 were 17.5% and 13.8% higher in rate of colony foundation and queen production, respectively, than other wake-up treatments. These results show that the most favorable wake-up treatment just before rearing for egg-laying and colony developmental characteristics of B. ignitus and B. terrestris queens was 24L-1. Overall, our findings indicate that a wake-up treatment just before rearing was effective for colony initiation and colony development of bumblebee queens.
Modeling the output ratio in air for megavoltage photon beams (2001)

The output ratio in air, OR, for a high-energy x-ray beam describes how the incident central axis photon fluence varies with collimator setting. For field sizes larger than 3 x 3 cm2, its variation is caused by the scatter of photons in structures in the accelerator head (primarily the flattening filter and the wedge, if one is used) and by the backscatter of radiation into the monitor ionization chamber. The objective of this study was to evaluate the use of an analytical function to parametrize OR for square collimator setting c: OR = (1 + a1.c).[1 + a2.erf(c/lambda)2].H0. For open beams, these parameters can be attributed to explicit physical meanings within the systematical uncertainty of the model: a1 accounts for backscatter into the monitor, a2 is the maximum scatter-to-primary ratio for head-scattered photons, and lambda represents the effective width of the "source" of head-scatter photons. H0 is a constant that sets OR = 1 for c = 10 cm. This formula also fits OR for wedge beams and a Co-60 unit, although the fitting parameters lose their physical interpretations. To calculate the output ratio for a rectangular field, cx x cy, an equivalent square can be used: c = (1 + k).cy x cx/(k.cx + cy), where k is a constant. The study included a number of different accelerators and a cobalt-60 unit. The fits for square fields agreed with measurements with a standard deviation (SD) of less than 0.5%. Using k = lx.(f - ly)/ly.(f - lx), where lx and ly are the source-to-collimator distances and f is the source-to-detector distance, measurements and calculations agreed within a SD of 0.7% for rectangular fields. Sufficient data for the three parameters are presented to suggest constraints that can be used for quality assurance of the measured output ratio in air.
Mitoxantrone: A New Anticancer Drug with Significant Clinical Activity (1986)

Clinical studies using mitoxantrone, an anthraquinone, were begun in the United States in 1979. Subsequent phase II and III trials have shown that mitoxantrone has significant clinical activity in patients with breast cancer, acute leukemia, and lymphoma. The drug has antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic properties and is mutagenic in some animal systems. Its mechanism of action seems to involve both DNA intercalation and nonintercalative electrostatic interactions. The dose-limiting toxicity is myelosuppression when the drug is given on a single-dose, every-3-week schedule and mucositis when it is given daily for 5 days. Other toxicities include gastrointestinal and cardiac effects, the gastrointestinal toxicity being less severe and less frequent than that with the anthracycline anticancer drugs. Because of its low incidence of serious toxicities and effectiveness in treating certain solid tumors and leukemias, mitoxantrone is a promising new agent in the treatment of cancer.
Cytolytic T‐cell response to the PASD1 cancer testis antigen in patients with diffuse large B‐cell lymphoma (2009)

The identification of immunogenic cancer testis antigens (CTAs) as immunotherapeutic targets represents one approach to improve treatment options for diffuse large B-cell lymphoma (DLBCL). We previously identified PASD1 [PAS (Per ARNT Sim) domain containing 1 (PASD1)], a DLBCL-associated CTA that was expressed in a range of hematopoietic malignancies. The aim of the present study was to investigate the presence of a cytotoxic T-cell (CTL) response to PASD1 in DLBCL patients. A significant gamma-interferon (IFN) release was detected in 21/29 HLA-A*0201-positive DLBCL patients (18 de novo DLBCL, two transformed DLBCL and one T-cell rich B-cell lymphoma) following short-term culture of their peripheral blood mononuclear cells stimulated with five HLA-A*0201-restricted PASD1 peptides. No significant responses were detected in 21 HLA-A*0201-negative DLBCL patients (12 de novo DLBCL, seven transformed DLBCL, two T-cell rich B-cell lymphoma) or six normal subjects. CTL cell lines were able to lyse PASD1-positive tumour cells in a major histocompatibility complex-Class I dependent manner. The presence of a gamma-IFN response correlated with PASD1 protein expression in the tumour cells in 12/15 cases studied. This is the first report of a CTL response to a CTA in DLBCL. Our results provide additional valuable evidence supporting PASD1 as a potential immunotherapeutic target for the treatment of DLBCL and other malignancies.
Magnesium and zinc complexes of a potentially tridentate β-diketiminate ligand (2004)

The synthesis of the unsymmetrically substituted beta-diketimine, 2-(2-methoxyphenylimino)-4-(2,6-diisopropylphenylamido)pent-2-ene, (BDI-2)H, is described and its complexation chemistry with magnesium and zinc is explored. Emphasis is placed on the preparation of alkoxide and amide derivatives for the ring-opening polymerisation of lactide; their behaviour as polymerisation initiators is compared to analogous compounds supported by the N,N'-bis(2,6-diisopropylphenyl) beta-diketiminate ligand, BDI-1. (BDI-2)H reacts with Me2Mg to give the bis(chelate) complex, (BDI-2)2Mg, 3. Magnesium alkyls supported by BDI-2 may be prepared by increasing the size of the alkyl group. Hence, lithiation of (BDI-2)H affords [(BDI-2)Li]2, 4; its subsequent treatment with iPrMgCl produces (BDI-2)MgiPr, 5. Aminolysis of complex using iPr2NH yields the amide complex, (BDI-2)MgNiPr2, 6. Zn(NTMS2)2 and ZnEt2 react with (BDI-2)H to give (BDI-2)Zn(NTMS2), 7, and (BDI-2)ZnEt, 8, respectively. The former is converted into the siloxide complex, (BDI-2)Zn(OSiPh3), 9, upon reaction with Ph3SiOH. The chloride derivative, (BDI-2)ZnCl, 10, has also been prepared via the reaction of ZnCl2 with 4. Crystallographic analysis of compounds, and reveals that the potential for (BDI-2) to bind in a tridentate manner is only realised with the more electrophilic metals Li and Mg. Compared to their (BDI-1) counterparts, complexes 6, 7 and 9 are more active, but less well-controlled, initiators for the ring-opening polymerisation of rac-lactide, a consequence of the diminished steric protection afforded by (BDI-2) relative to (BDI-1).
ChemInform Abstract: PROTOTYPE SOLAR CELL USED IN AMMONIA PROCESS (1978)

Abstract Beim Cberleiten von feuchtem Stickstoff über feinverteiltes Titandioxid als Katalysator wird in Gegenwart von starkem Sonnenlicht Ammoniak gebildet.
iWebDB-Web site administration based on object-relational database technology (2003)

Since the emergence of the World Wide Web in the year 1990, the number of accessible Web servers, HTML pages, and thereby the amount of accessible data have increased dramatically. Consequently many people around the world are engaged in maintaining a Web server and its content. While creating HTML pages is getting more and more simple, the administration of a Web site is still a time consuming and demanding task. Available tools for Web Content Management (WCM) only cover some of the relevant aspects of the whole task; an integrated fully functional solution is missing. Therefore, Web administrators still have to cope with many problems, such as ensuring validity of available documents or keeping hyperlinks consistent. We present administrative components of iWebDB, an integrated WCM solution, based on object-relational database technology. By extending an object-relational database system (ORDBS) with WCM functionality, many tasks of WCM, such as validity checks and consistency checks for local hyperlinks, can be delegated to the DBS and thereby automated. Therefore, iWebDB achieves more effective and easier administration of a Web server and its content by exploiting the extensibility property of ORDBSs.
New Source Compounds For Fabrication Of Doped Optical Waveguide Fibers (1984)

Raw materials used for the fabrication of high purity Si02-Ge02 glasses are typically volatile metal halides. The use of non-halides has been reported but have not been extensively utilized. New compositions for optical fibers have been proposed to extend optical performance and fabrication efficiency but these are often unattainable due to lack of suitably volatile high purity source compounds compatable with CVD systems. A recent approach to obtain waveguides more resistant to detrimental radiation effects is the addition of metal oxides such as cerium oxide that are widely used in specialty glasses to minimize induced absorptions caused by ionizing radiation by creation of hole and electron traps. Optical Waveguide fibers in the Si02-Ge02-Ce02 system have been fabricated by conventional OVD processes utilizing newly developed cerium source compounds. These new compounds are transported from bubblers using argon carrier gas to the burner where methane-oxygen combustion in the presence of SiCl4 and GeCl4 produces ceria containing glass of optical waveguide quality. Cerium (III) and Ce (IV) are observed at 260 and 320nm, respectively, in transmission curves of bulk pieces of glass and also optical fibers. Ceria concentrations over 0.4% (wt) induce phase separation so attenuation measurements have been on fiber containing less Ce02. No deleterous effects of absorption due to CeO2 occur beyond 850nm based upon comparisons of control and doped fibers. Results of preliminary radiation exposure will also be presented.
MeetingCoach: An Intelligent Dashboard for Supporting Effective & Inclusive Meetings (2021)

Video-conferencing is essential for many companies, but its limitations in conveying social cues can lead to ineffective meetings. We present MeetingCoach, an intelligent post-meeting feedback dashboard that summarizes contextual and behavioral meeting information. Through an exploratory survey (N=120), we identified important signals (e.g., turn taking, sentiment) and used these insights to create a wireframe dashboard. The design was evaluated with in situ participants (N=16) who helped identify the components they would prefer in a post-meeting dashboard. After recording video-conferencing meetings of eight teams over four weeks, we developed an AI system to quantify the meeting features and created personalized dashboards for each participant. Through interviews and surveys (N=23), we found that reviewing the dashboard helped improve attendees’ awareness of meeting dynamics, with implications for improved effectiveness and inclusivity. Based on our findings, we provide suggestions for future feedback system designs of video-conferencing meetings.
Bar 1-visibility representation of optimal 1-planar graph (2014)

In a visibility representation of a graph, the vertices map to objects in Euclidean space and the edges are determined by certain visibility relations. A bar visibility representation of a planar graph is a drawing where each vertex is drawn as a horizontal line segments called bars, each edge is drawn as a vertical line segment where the vertical line segment representing an edge must connect the horizontal line segments representing the end vertices. A graph is called a 1-planar graph if it can be drawn in the plane so that each its edge is crossed by at most one other edge. A 1-planar graph is said to be optimal if there are highest number of edges available. In this Research, we proposed an algorithm to numbering the optimal 1-planar graph and also bar 1-visibility representation of optimal 1-planar graph.
Modelling the frequency of contacts in a shrunken world (2008)

Based on a new substantial Swiss survey of ego-centric networks this paper analysis the impact of precisely measured geographical distance on the frequency and shares of different modes of interaction between the respondents and their contacts (face-to-face, phone, email and SMS texting).Geographical distance matters to how people interact today, as it did in the past (Mok and Wellman, 2007).The effort involved in the different modes of contact (face-toface, phone, email and SMS) matches qualitatively the strength of the distance decay in the frequency of those interactions.The qualitative results are confirmed in structural equation model allowing for panel/multi-level nature of the data set.The patterns of the shares follow these differential distance decays.The frequency of face-to-face visits and their shares fall quickest with distance.While email frequency is unaffected by distance, its share rises fastest with it.The reverse is true for SMS messaging, which stays stable in terms of share, while only slowly falling with distance in terms of frequency.The high starting frequency of phoning translates into growing shares, even if the absolute frequencies fall with distance.
Monte Carlo study of impact ionization phenomena in small geometry MOSFET's (2002)

We developed a multi-valley Monte Carlo simulator in which realistic physical parameters based on ab-initio calculations are implemented. A nonlocal impact ionization coefficient in exponentially increasing field is extracted using the Monte Carlo simulator. On the basis of the new nonlocal impact ionization coefficient, an analytical substrate current expression for n-MOSFET's is derived. The new substrate current expression clarifies the reason why a reported theoretical characteristic length used in a pseudo two-dimensional MOSFET model differs from empirically derived ones. The nonlocal impact ionization coefficient implemented in a device simulator demonstrates that the new coefficient can predict substrate current correctly in the framework of the drift diffusion model.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A real time coincidence system for high count-rate TOF or non-TOF PET cameras using hybrid method combining AND-logic and Time-mark technology (2009)

A fully digital FPGA-based high count-rate coincidence system has been developed for TOF and non-TOF PET cameras. Using hybrid method combining AND-logic and Time-mark technology can gain both excellent timing resolution and high processing speed. In this hybrid architecture, every gamma event is synchronized by a 125 MHz system clock and generating a trigger associated with a time-mark given by an 8-bit high-resolution TDC (68.3 ps/bin). AND-logic is applied to the synchronized triggers for real-time raw sorting of coincident events. An efficient FPGA based Time-mark fine-sort algorithm is used to select all the possible coincidence events within the preset coincidence time window. This FPGA-based coincidence system for modular PET camera offers reprogrammable flexibility and expandability, so the coincidence system is easily employed for different scale of PET camera detector setup. Distributed processing method and pipeline technology is adopted in the design to obtain very high processing speed. Both prompt and time-delayed accidental coincidences are simultaneously processed in real time. The real-time digital coincidence system supports coincidence between 2 to 12 detector modules setup, capable of processing 72 millions single events per second with no dead-time and captures triple events coincidence for better imaging performance evaluation. The coincidence time window-size and time-offset of each coincidence event pair can be programmed independently in the step of 68.3 ps (TDC LSB) during the data acquisition in different applications to optimize the signal-to-noise ratio. The complex coincidence system is integrated in one (A4 size) circuit board with 1.5 Gbps fiber optical interface. We have evaluated the system performance using the actual circuit and Monte Carlo simulations.
HPLC Determination of Caffeine and Theobromine in Coffee, Tea, and Instant Hot Cocoa Mixes (1983)

ABSTRACT Popular brands of instant and ground coffee, instant and bag tea, and instant hot cocoa mixes were prepared according to manufacturer's directions and analyzed for caffeine and/or theobromine content. After extraction into boiling water, the methylxanthines were separated by high performance liquid chromatography using a reverse phase C 18 column and a mobile phase of acetonitrile and water (8:92, v/v). Caffeine content ranged from 32.4–35.0 mg/cup in instant tea, 30.2–67.4 mg/cup in bag tea, 1.0–7.8 mg/cup in instant hot cocoa mixes, 46.7–67.6 mg/cup in instant coffee, and 93.0–163.5 mg/cup in ground coffee. Theobromine concentrations ranged from 1.4–2.3 mg/cup in instant tea, 1.2–4.4 mg/cup in bag tea, and 39.5–79.5 mg/cup in instant hot cocoa mixes.
Treatment of ulcerative colitis with an engineered human anti‐TNFα antibody CDP571 (1997)

A consistent improvement in disease activity was seen in the initial 2 weeks after infusion and the treatment was well tolerated. These promising results support the testing of CDP571 in a larger controlled trial.