gebhart/patrepeval huggingface dataset:
Anomaly Detection for Container Cluster based on JointCloud Platform (2019)

In order to accurately discover container exception data of large-scale container clusters to guide the maintenance of container clusters, a new anomaly detection model for container clusters is proposed in this article. The model combines the advantages of supervised learning and unsupervised learning to accurately and efficiently label container anomaly data in a large-scale data environment. Experiments show that the labeling rate of the raw data is as high as 95.6%, and the accuracy of anomaly detection is as high as 87.0%. Simultaneously, the common five classification algorithms are used to compare the anomaly detection effect between the labeled data and the raw data, and the validity of the model is further verified.
Wideband Channel Estimation and Prediction in Single-Carrier Wireless Systems (2005)

Wideband channel estimation and prediction designed for single-carrier wideband wireless communications systems are investigated. Specifically, the single-carrier wideband pilot signal received by the receiver is first converted to the frequency-domain. Then, the envelope of the channel transfer function (CTF) is estimated in the frequency-domain, in order to reduce the effects of background noise on the channel prediction step to be invoked. Finally, channel prediction is carried out based on the estimated CTF in the frequency-domain, where a Kalman filter-assisted long-range channel prediction algorithm is employed. Simulation results show that, for a reasonable signal-to-noise ratio (SNR) value, the proposed frequency-domain based wideband channel estimator is capable of efficiently mitigating the effects of the background noise, hence enhancing the performance of wideband channel prediction.
Bacterial Meningitis: Recent Advances in Pathophysiology and Treatment (1990)

Future therapy for bacterial meningitis will use recent developments in the understanding of pathogenic and pathophysiologic mechanisms underlying this disease. Additional studies using monoclonal antibodies against specific virulence factors and investigations into the production of inflammatory cytokines in response to bacterial cell products may lead to additional treatments that decrease the high morbidity and mortality in patients with bacterial meningitis.
Pico: A Domain-Specific Language For Data Analytics Pipelines (2017)

In the world of Big Data analytics, there is a series of tools aiming at simplifying programming applications to be executed on clusters. Although each tool claims to provide better programming, data and execution models—for which only informal (and often confusing) semantics is generally provided—all share a common under- lying model, namely, the Dataflow model. Using this model as a starting point, it is possible to categorize and analyze almost all aspects about Big Data analytics tools from a high level perspective. This analysis can be considered as a first step toward a formal model to be exploited in the design of a (new) framework for Big Data analytics. By putting clear separations between all levels of abstraction (i.e., from the runtime to the user API), it is easier for a programmer or software designer to avoid mixing low level with high level aspects, as we are often used to see in state-of-the-art Big Data analytics frameworks. From the user-level perspective, we think that a clearer and simple semantics is preferable, together with a strong separation of concerns. For this reason, we use the Dataflow model as a starting point to build a programming environment with a simplified programming model implemented as a Domain-Specific Language, that is on top of a stack of layers that build a prototypical framework for Big Data analytics. The contribution of this thesis is twofold: first, we show that the proposed model is (at least) as general as existing batch and streaming frameworks (e.g., Spark, Flink, Storm, Google Dataflow), thus making it easier to understand high-level data-processing applications written in such frameworks. As result of this analysis, we provide a layered model that can represent tools and applications following the Dataflow paradigm and we show how the analyzed tools fit in each level. Second, we propose a programming environment based on such layered model in the form of a Domain-Specific Language (DSL) for processing data collections, called PiCo (Pipeline Composition). The main entity of this programming model is the Pipeline, basically a DAG-composition of processing elements. This model is intended to give the user an unique interface for both stream and batch processing, hiding completely data management and focusing only on operations, which are represented by Pipeline stages. Our DSL will be built on top of the FastFlow library, exploiting both shared and distributed parallelism, and implemented in C++11/14 with the aim of porting C++ into the Big Data world.
Biomimetic mineralization (2006)

Biomimetic mineralization is a powerful approach for the synthesis of advanced materials with complex shape, hierarchical organization and controlled size, shape and polymorph under ambient conditions in aqueous environments. Increased understanding of biomineralization mechanisms has greatly enhanced the possibilities of biomimetic mineralization approaches. This overview tries to capture the concepts and recent progress in this rapidly developing field.
Advanced Insulin Bolus Advisor based on Run-To-Run Control and Case-Based Reasoning (2014)

This paper presents an advanced insulin bolus advisor for people with diabetes on multiple daily injections or insulin pump therapy. The proposed system, which runs on a smartphone, keeps the simplicity of a standard bolus calculator while enhancing its performance by providing more adaptability and flexibility. This is achieved by means of applying a retrospective optimization of the insulin bolus therapy using a novel combination of run-to-run (R2R) that uses intermittent continuous glucose monitoring data, and case-based reasoning (CBR). The validity of the proposed approach has been proven by in-silico studies using the FDA-accepted UVa-Padova type 1 diabetes simulator. Tests under more realistic in-silico scenarios are achieved by updating the simulator to emulate intrasubject insulin sensitivity variations and uncertainty in the capillarity measurements and carbohydrate intake. The CBR(R2R) algorithm performed well in simulations by significantly reducing the mean blood glucose, increasing the time in euglycemia and completely eliminating hypoglycaemia. Finally, compared to an R2R stand-alone version of the algorithm, the CBR(R2R) algorithm performed better in both adults and adolescent populations, proving the benefit of the utilization of CBR. In particular, the mean blood glucose improved from 166 ± 39 to 150 ± 16 in the adult populations (p = 0.03) and from 167 ± 25 to 162 ± 23 in the adolescent population (p = 0.06). In addition, CBR(R2R) was able to completely eliminate hypoglycaemia, while the R2R alone was not able to do it in the adolescent population.
Optical, Fluorescent, and (Photo)conductive Properties of High-Performance Functionalized Pentacene and Anthradithiophene Derivatives (2009)

The optical, fluorescent, and photoconductive properties of solution-processable functionalized pentacene and anthradithiophene (ADT) derivatives are presented. Considerable fluorescence quantum yields of ∼70−75% and ∼40−50% were observed in several ADT derivatives in toluene solutions and in thin films, respectively. No electric field-induced fluorescence quenching was observed in films at applied electric fields of up to at least 2 × 105 V/cm. Strong temperature dependence of fluorescence quantum yields was observed in all ADT films but not solutions, which emphasizes importance of intermolecular interactions in these materials. All films exhibited fast charge carrier photogeneration upon 100 fs 400 nm excitation and power-law decay dynamics of the transient photocurrent over many orders of magnitude in time. In solution-deposited ADT thin films, effective charge carrier mobilities calculated from the space-charge-limited currents reached ∼0.1 cm2/V·s. In the same films, bulk photoconductive gains of up to 130 were observed at 532 nm continuous wave excitation with light intensity of 0.58 mW/cm2 at the applied electric field of 4 × 104 V/cm.
Improvement of mammalian cell culture performance through surfactant enabled concentrated feed media (2013)

The design of basal and feed media in mammalian cell culture is paramount towards ensuring acceptable upstream process performance in various operation modes, especially fed-batch culture. Mammalian cell culture media designs have evolved from the classical formulations designed by Eagle and Ham, to today's formulations designed from continuous improvement and statistical frameworks. Feed media is especially important for ensuring robust cell growth, productivity, and ensuring the product quality of recombinant therapeutics are within acceptable ranges. Numerous studies have highlighted the benefit of various media designs, supplements, and feed addition strategies towards the resulting cell culture process. In this work we highlight the use of a top-down level approach towards feed media design enabled by the use of select surfactants for the targeted enrichment of a chemically defined feed media. The use of the enriched media was able to improve product titers at g/L levels, without adversely impacting the growth of multiple Chinese Hamster Ovary cell lines or the product quality of multiple recombinant antibodies.
Increasing situation awareness of the CBRNE robot operators (2010)

Situational awareness of CBRN robot operators is quite limited, as they rely on images and measurements from on-board detectors. This paper describes a novel framework that enables a uniform and intuitive access to live and recent data via 2D and 3D representations of visited sites. These representations are created automatically and augmented with images, models and CBRNE measurements. This framework has been developed for CBRNE Crime Scene Modeler (C2SM), a mobile CBRNE mapping system. The system creates representations (2D floor plans and 3D photorealistic models) of the visited sites, which are then automatically augmented with CBRNE detector measurements. The data stored in a database is accessed using a variety of user interfaces providing different perspectives and increasing operators' situational awareness.
The 121‐contiguous‐subfield addressing of high Xe‐content PDPs (2005)

Abstract— As the Xe content of PDPs is increased, the space‐charge priming becomes more effective. Also, the diffusion/drift of the space charges and accumulation of the wall charges becomes faster. These facts indicate that the use of an erase addressing is preferable for high‐Xe‐content PDPs. A 30%‐Xe green test panel was driven with contiguous subfields using erase addressing and a grouped Address‐While‐Display scheme. Crosstalk was suppressed by driving the odd and even sustain electrodes separately. The fast addressing speed of 0.283 μsec allowed for 121 subfields and 122 gray levels, with a resultant luminance of 4200 cd/m 2 and a dark‐room contrast of 310:1. The scan and data pulse voltages were as low as 90 and 75 V, respectively. All the subfields had an identical length of 136 μsec, but the number of sustain pulses in these subfields could be varied between 2 and 20. By selecting an adequate number of sustain pulses in the subfields, arbitrary gamma characteristics could be realized. A gray‐scale expression having a constant difference between the consecutive “perceived” luminance levels was verified throughout all the luminance levels.
Structural study of histamine H<sub>2</sub>-receptor antagonists. Five 3-[2-(diaminomethyleneamino)-4-thiazolylmethylthio]propionamidine and -amide derivatives (1989)

(1) N2-Cyano-3-[2-(diaminomethyleneamino)-4- thiazolylmethylthio]propionamidine monohydrate, C9H13N7S2.H2O, Mr = 301.39, P1, a = 11.089 (4), b = 9.130 (6), c = 7.033 (5) A, alpha = 100.99 (6), beta = 83.86 (5), gamma = 86.80 (7) degrees, V = 692.9 (6) A3, Z = 2, Dm = 1.443 (2), Dx = 1.444 g cm-3, lambda(Cu K alpha) = 1.5418 A, mu = 34.86 cm-1, F(000) = 316, T = 293 K, R = 0.043 for 2219 reflections. (2) 3-[2-Diaminomethyleneamino)-4- thiazolylmethylthio]-N2-sulfamoylpropionamidine (famotidine) hydrochloride, C8H15N7O2S3.HCl, Mr = 373.90, Cc, a = 15.205 (3), b = 14.442 (3), c = 9.262 (1) A, beta = 124.00 (5) degrees, V = 1686.1 (7) A3, Z = 4, Dm = 1.470 (2), Dx = 1.473 g cm-3, mu(Cu K alpha) = 56.09 cm-1, F(000) = 776, T = 293 K, R = 0.036 for 1411 reflections. (3) 3-[2-(Diaminomethyleneamino)-4-thiazolylmethylthio]-propi ona mide, C8H13N5OS2, Mr = 259.35, P2(1)2(1)2(1), a = 5.472 (1), b = 18.260 (5), c = 11.890 (3) A, V = 1188.0 (5) A3, Z = 4, Dm = 1.448 (1), Dx = 1.450 g cm-3, mu(Cu K alpha) = 39.26 cm-1, F(000) = 544, T = 293 K, R = 0.036 for 1260 reflections.(ABSTRACT TRUNCATED AT 250 WORDS)
Graphene: A Platform for Surface‐Enhanced Raman Spectroscopy (2013)

Surface-enhanced Raman spectroscopy (SERS) imparts Raman spectroscopy with the capability of detecting analytes at the single-molecule level, but the costs are also manifold, such as a loss of signal reproducibility. Despite remarkable steps having been taken, presently SERS still seems too young to shoulder analytical missions in various practical situations. By the virtue of its unique molecular structure and physical/chemical properties, the rise of graphene opens up a unique platform for SERS studies. In this review, the multi-role of graphene played in SERS is overviewed, including as a Raman probe, as a substrate, as an additive, and as a building block for a flat surface for SERS. Apart from versatile improvements of SERS performance towards applications, graphene-involved SERS studies are also expected to shed light on the fundamental mechanism of the SERS effect.
Exploiting the Reversibility of Olefin Metathesis. Syntheses of Macrocyclic Trisubstituted Alkenes and (<i>R,R</i>)-(−)-Pyrenophorin (2001)

[figure: see text] The formation of the trisubstituted cycloalkene 7 by RCM of diene 5 proceeds via the acyclic dimer 6, thus demonstrating the ready reversibility of olefin metathesis if catalyzed by "second generation" ruthenium carbene complexes such as 2-4. When applied to acrylate 11, these catalysts trigger a cyclooligomerization process that evolves with time and serves as key step en route to the lactide antibiotic (-)-pyrenophorin 8.
Cooperation and virulence in acute Pseudomonas aeruginosainfections (2006)

These data demonstrate that mixed clone infections can favour the evolution of social cheats, and thus decrease virulence when parasite growth is dependent on cooperative behaviours.
Replication of alpha and beta globin DNA sequences occurs during early S phase in murine erythroleukemia cells. (1981)

Murine erythroleukemia cells (MELC) can be induced to express the characteristics of erythroid differentiation by a variety of agents. Previous studies indicate that an action of inducer, occurring during early S phase, may be critical to the expression of differentiated characteristics such as initiation of accumulation of newly synthesized alpha and beta globin mRNAs. In this investigation, the time of replication of globin genes in MELC was studied. DNA was isolated from synchronous populations of cells obtained by centrifugal elutriation. Newly replicated DNA sequences were prepared from synchronized cells cultured for 1 1/2 hr with 5-bromodeoxyuridine; bromodeoxyuridine-containing DNA was isolated by CsCl gradient centrifugation. By employing cloned probes for hybridization to newly synthesized DNA, it was found that alpha and beta globin gene sequences are replicated early in S phase, while ribosomal RNA gene sequences are replicated to about the same extent in early, middle, and late S phases.
Blood circulation and fluid dynamics in the eye (1975)

The nutrition of the intraocular tissues is accomplished by the retinal vessels, the uveal vessels, and by the aqueous humor. Both morphologically and physiologically the retinal vessels are similar to those in the brain. The endothelial cells of the capillaries are attached to each other by tight junctions, the resistance vessels respond poorly to a large number of drugs, and the blood flow through the retina is autoregulated and very little affected by the sympathetic nervous system. The blood vessels of the iris also have morphological and permeability characteristics similar to those in the brain but they are under a strong influence from the sympathetic nerves and react to many drugs. The blood flow is autoregulated. The blood vessels of the choroid and the ciliary processes are similar to those in the small intestine and in the kidney. The endothelial cells of the capillaries are fenestrated; the vessels respond to sympathetic nervous stimulation and to a large number of vasoactive drugs. Autoregulation of the blood flow is intermediate in the ciliary body and very poor or absent in the choroid...
Sleep disorders in Parkinson's disease (2002)

We sought to estimate the frequency and nature of sleep disturbances in Indian Parkinson's disease (PD) patients. One hundred forty nine consecutive PD patients attending the Movement Disorders Clinic of the All India Institute of Medical Sciences, New Delhi, India and 115 age-matched healthy controls participated. After clinical evaluation, sleep assessment was done using a 23-question, validated sleep questionnaire. Mean age of PD patients and the duration of illness were 58.37 (S.D. 10.45) years and 5.7 (S.D. 3.85) years, respectively. The mean age of the controls was 56.50 (S.D. 11.45) years (P > 0.05). Sleep problems were seen in 63 (42%) PD patients compared to 12% of controls. These were: insomnia in 32%, nightmares in 32%, and excessive day time sleepiness in 15% of PD patients as compared with 5%, 5% and 6%, respectively, in controls (P < 0.025). Presence of nightmares was significantly associated with higher Hoehn and Yahr score (P < 0.002), high unified Parkinson's disease rating scale (UPDRS) Part I score (P < 0.000) and levodopa dose (P < 0.025). Excessive daytime sleepiness correlated with higher Hoehn and Yahr stage (P < 0.004), and levodopa dose (P < 0.040). The sleep latency was longer in PD patients as compared to controls (P < 0.000). Multiple logistic regression analysis showed association of sleep disturbances with UPDRS Part III, Schwab and England score, levodopa dose, rigidity score, and bradykinesia score. Sleep problems are much more common in PD patients compared to controls (P < 0.001), and correlate with increased severity of disease.
The effect of calcium precipitating substances on the ciliated epithelium of the maxillary sinus (1931)

Abstract 1.1. The movement of the cilia of the maxillary sinus mucosa stops when alizarin, citrate or oxalate is added to the medium. 2.2. The maxillary sinuses of rabbits and rats irrigated five times at forty-eight hour intervals with sodium alizarin sulphonate showed a disappearance of cilia and infiltration of eosinophiles into the basement membrane. Three months after the last irrigation rats showed chronic sinusitis. 3.3. Sodium citrate and ammonium oxalate produced similar changes in the sinus mucosa of rabbits. 4.4. Sodium chloride produced the appearance of eosinophiles in the basement membrane of the sinus mucosa. 5.5. Potassium chloride irrigations resulted in marked histologic changes. 6.6. Calcium chloride was ineffective in producing any histologic change.
Fast fully dynamic landmark-based estimation of shortest path distances in very large graphs (2011)

Computing the shortest path between a pair of vertices in a graph is a fundamental primitive in graph algorithmics. Classical exact methods for this problem do not scale up to contemporary, rapidly evolving social networks with hundreds of millions of users and billions of connections. A number of approximate methods have been proposed, including several landmark-based methods that have been shown to scale up to very large graphs with acceptable accuracy. This paper presents two improvements to existing landmark-based shortest path estimation methods. The first improvement relates to the use of shortest-path trees (SPTs). Together with appropriate short-cutting heuristics, the use of SPTs allows to achieve higher accuracy with acceptable time and memory overhead. Furthermore, SPTs can be maintained incrementally under edge insertions and deletions, which allows for a fully-dynamic algorithm. The second improvement is a new landmark selection strategy that seeks to maximize the coverage of all shortest paths by the selected landmarks. The improved method is evaluated on the DBLP, Orkut, Twitter and Skype social networks.
Arabidopsis Root-Type Ferredoxin:NADP(H) Oxidoreductase 2 is Involved in Detoxification of Nitrite in Roots (2016)

Ferredoxin:NADP(H) oxidoreductase (FNR) plays a key role in redox metabolism in plastids. Whereas leaf FNR (LFNR) is required for photosynthesis, root FNR (RFNR) is believed to provide electrons to ferredoxin (Fd)-dependent enzymes, including nitrite reductase (NiR) and Fd-glutamine-oxoglutarate aminotransferase (Fd-GOGAT) in non-photosynthetic conditions. In some herbal species, however, most nitrate reductase activity is located in photosynthetic organs, and ammonium in roots is assimilated mainly by Fd-independent NADH-GOGAT. Therefore, RFNR might have a limited impact on N assimilation in roots grown with nitrate or ammonium nitrogen sources. AtRFNR genes are rapidly induced by application of toxic nitrite. Thus, we tested the hypothesis that RFNR could contribute to nitrite reduction in roots by comparing Arabidopsis thaliana seedlings of the wild type with loss-of-function mutants of RFNR2 When these seedlings were grown under nitrate, nitrite or ammonium, only nitrite nutrition caused impaired growth and nitrite accumulation in roots of rfnr2 Supplementation of nitrite with nitrate or ammonium as N sources did not restore the root growth in rfnr2 Also, a scavenger for nitric oxide (NO) could not effectively rescue the growth impairment. Thus, nitrite toxicity, rather than N depletion or nitrite-dependent NO production, probably causes the rfnr2 root growth defect. Our results strongly suggest that RFNR2 has a major role in reduction of toxic nitrite in roots. A specific set of genes related to nitrite reduction and the supply of reducing power responded to nitrite concomitantly, suggesting that the products of these genes act co-operatively with RFNR2 to reduce nitrite in roots.
Role of aspartic proteases in disseminated Candida albicans infection in mice (1997)

A murine model of disseminated candidiasis involving intranasal challenge with Candida albicans was developed and used to explore the role of C. albicans aspartic proteases as virulence factors during early dissemination. Pretreatment of neutropenic mice with the aspartic protease inhibitor pepstatin A by intraperitoneal injection afforded strong dose-dependent protection against a subsequent lethal intranasal dose of an aspartic protease-producing strain (ATCC 32354) of C. albicans. Administration of 0.6 mg of pepstatin A kg of body weight(-1) prior to challenge and on days 1 to 4 postchallenge resulted in 100% survival at day 15 postchallenge, whereas 100% of animals receiving saline had died by day 6. This effect was comparable to the dose-dependent protection obtained with amphotericin B, which resulted in 100% survival when administered at 0.1 mg kg(-1). The reduction in mortality afforded by pepstatin A correlated with its dose-dependent blockade of C. albicans numbers in the lungs, liver, and kidneys. By sharp contrast, no protection by pepstatin A was observed in mice challenged intravenously, and protection was markedly attenuated in mice given pepstatin A after intranasal challenge only. These data show the utility of pepstatin A in the prophylaxis of disseminated Candida infections and suggest that Candida aspartic proteases play an essential role early in dissemination.