gebhart/patrepeval huggingface dataset:
Analysis of obstetric patients treated in general intensive care units (1997)

The critically ill obstetric patients who require intensive care are few and a multidisciplinary intensive care unit (ICU) is often used to care for these patients. This study reports characteristics of obstetric patients treated in general ICUs of our hospital from 1985 to 1996. A retrospective review of all obstetric patients who were cared for in the general ICU of our hospital from 1985 to 1996 was undertaken. The reasons of admission to an ICU, morbidity, duration of ICU stay and outcome were examined. Forty cases, one peripartum and 30 post-partum, were identified; 18 of the latter (46%) were referred from other hospitals and seven of them were associated with intrauterine death of the foetus. One patient with severe asthma was admitted to the ICU for peripartum respiratory care. The primary obstetric complication was abruptio placantae in five, preeclampsia/eclampsia in 15, postpartum haemorrhage in eight, puerperal sepsis in one and amniotic fluid embolism in one. There were 10 patients with nonobstetric conditions including cardiac disease in four, haematological disorders in three, hyperthyroidism, asthma and pulmonary thromboembolism in one, respectively. Severe morbidity was found in 17 patients (43%); pulmonary embolism in two, pulmonary oedema in two, acute renal failure in eight, HELLP syndrome in two, pneumonia in one and disseminated intracoagulopathy in 10. A patient with pulmonary embolism secondary to amniotic fluid embolism did not respond to cardiopulmonary resuscitation. Another patient with post-partum pulmonary thromboembolism was successfully treated with pulmonary thrombectomy. Only one of the patients with acute renal failure required haemodialysis. In three of eight patients with post-partum haemorrhage, a massive blood transfusion over 10 mL was given peri-operatively. Twenty-four of 40 patients (60%) including all the patients with post-partum haemorrhage and eight with non-obstetric disorders had a smooth course and were discharged from the ICU within 24 h. Five patients stayed in the ICU over 1 week, and nine patients stayed for 2-4 days. Most of them were related to preeclampsia/eclampsia. This study reconfirmed that proper pre-natal care is essential for reducing post-partum morbidity and that pre-eclampsia/eclampsia remains a significant complication with high morbidity. Considering the number of critically ill obstetric patients who require intensive care, it appears that the general ICU is the most practical and economic facility to care for these patients.
A NEW AFFINITY RESIN FOR PURIFICATION OF NON-TRANSFORMED AVIAN PROGESTERONE RECEPTOR (1982)

A new steroid affinity resin has been developed which can be successfully used to partially purify the non-transformed species of the progesterone receptor from chick oviduct. Deoxycorticosterone has been modified through its 21-carbon and linked to a stable spacer arm which is attached to Sepharose 2B by an epoxide technique. The affinity resin is very resistant to chemical breakdown or to enzymatic destruction in crude tissue extracts. We have standardized the capacity and optimum conditions for elution of receptor which is bound to the affinity resin. Receptor purification of several hundred-fold can be obtained routinely with good yield. The cytosol receptor prepared in the presence of sodium molybdate remains in the non-transformed 8S state following affinity chromatography.
An Experimental Evaluation of Three Classifiers for Use in Self-Updating Face Recognition Systems (2012)

Previous studies have shown that the accuracy of Face Recognition Systems (FRSs) decreases with the time elapsed between enrollment and testing. The main reason for the decrease is the changes in appearance of the user due to factors such as ageing, beard growth, sun-tan etc. Self-update procedure, where the system learns the biometric characteristics of the user every time he/she interacts with it, can be used to automatically update the system. However, a commonly acknowledged problem is the corruption of biometric traits due to misclassification. In this article, we test FRS, based on three classification algorithms, on two challenging databases, GEFA and YT, with 14 279 and 31 951 images, respectively. Our results suggest that complex, state-of-the-art classifiers that make use of user-specific models, need not be the best choice for use in self updating systems. In other words, tolerance to corrupted training data decreases as the complexity of the classifier increases.
A 65nm CMOS low-power small-size multistandard, multiband mobile broadcasting receiver SoC (2010)

For a few years, new mobile broadcasting services were launched in Korea, Japan, Europe and China. The mobile broadcasting markets are maturing rapidly for applications such as mobile cellular phones, car navigation, PMP and so on. The market drives low-cost, low-power and small size significantly for mobile applications and drives multiple functionality and multiple bands [1]. To meet the market requirements, more integration of system blocks and functionality is needed. To achieve this goal, the 65nm CMOS and multistandard and multiband receiver SoC may be suitable solution.
Template matching based people tracking using a smart camera network (2014)

In this paper, we proposes a people tracking system composed of multiple calibrated smart cameras and one fusion server which fuses the information from all cameras. Each smart camera estimates the ground plane positions of people based on the current frame and feedback from the server from the previous time. Correlation coefficient based template matching, which is invariant to illumination changes, is proposed to estimate the position of people in each smart camera. Only the estimated position and the corresponding correlation coefficient are sent to the server. This minimal amount of information exchange makes the system highly scalable with the number of cameras. The paper focuses on creating and updating a good template for the tracked person using feedback from the server. Additionally, a static background image of the empty room is used to improve the results of template matching. We evaluated the performance of the tracker in scenarios where persons are often occluded by other persons or furniture, and illumination changes occur frequently e.g., due to switching the light on or off. For two sequences (one minute for each, one with table in the room, one without table) with frequent illumination changes, the proposed tracker never lose track of the persons. We compare the performance of our tracking system to a state-of-the-art tracking system. Our approach outperforms it in terms of tracking accuracy and people loss.
Toward Optimal Transport Networks (2008)

Strictly evolutionary approaches to improving the air transport system a highly complex network of interacting systems no longer suffice in the face of demand that is projected to double or triple in the near future. Thus evolutionary approaches should be augmented with active design methods. The ability to actively design, optimize and control a system presupposes the existence of predictive modeling and reasonably well-defined functional dependences between the controllable variables of the system and objective and constraint functions for optimization. Following recent advances in the studies of the effects of network topology structure on dynamics, we investigate the performance of dynamic processes on transport networks as a function of the first nontrivial eigenvalue of the network's Laplacian, which, in turn, is a function of the network s connectivity and modularity. The last two characteristics can be controlled and tuned via optimization. We consider design optimization problem formulations. We have developed a flexible simulation of network topology coupled with flows on the network for use as a platform for computational experiments.
Chemo- and Regioselective Functionalization of Uracil Derivatives. Applications to the Synthesis of Oxypurinol and Emivirine (2006)

[reaction: see text] A novel route for the synthesis of 4,5-difunctionalized uracils using a chemo- and regioselective bromine/magnesium exchange reaction on 5-bromo-4-halogeno-2,6-dimethoxypyrimidines has been developed. Applications to the synthesis of pharmaceuticals such as oxypurinol and emivirine are reported.
EDITORIAL NOTE (1953)

EDITORIAL NOTE Get access J. B. J. B. Search for other works by this author on: Oxford Academic Google Scholar The Review of English Studies, Volume IV, Issue 14, April 1953, Page 97, https://doi.org/10.1093/res/IV.14.97 Published: 01 April 1953
Stereoselective construction of the C<sub>18</sub>–C<sub>32</sub>fragment of swinholide A (1994)

P. K. Richter, M. J. Tomaszewski, R. A. Miller, A. P. Patron and K. C. Nicolaou, J. Chem. Soc., Chem. Commun., 1994, 1151 DOI: 10.1039/C39940001151
Intracellular Implantation of Enzymes in Hollow Silica Nanospheres for Protein Therapy: Cascade System of Superoxide Dismutase and Catalase (2014)

An approach for enzyme therapeutics is elaborated with cell-implanted nanoreactors that are based on multiple enzymes encapsulated in hollow silica nanospheres (HSNs). The synthesis of HSNs is carried out by silica sol-gel templating of water-in-oil microemulsions so that polyethyleneimine (PEI) modified enzymes in aqueous phase are encapsulated inside the HSNs. PEI-grafted superoxide dismutase (PEI-SOD) and catalase (PEI-CAT) encapsulated in HSNs are prepared with quantitative control of the enzyme loadings. Excellent activities of superoxide dismutation by PEI-SOD@HSN are found and transformation of H2 O2 to water by PEI-CAT@HSN. When PEI-SOD and PEI-CAT are co-encapsulated, cascade transformation of superoxide through hydrogen peroxide to water was facile. Substantial fractions of HSNs exhibit endosome escape to cytosol after their delivery to cells. The production of downstream reactive oxygen species (ROS) and COX-2/p-p38 expression show that co-encapsulated SOD/CAT inside the HSNs renders the highest cell protection against the toxicant N,N'-dimethyl-4,4'-bipyridinium dichloride (paraquat). The rapid cell uptake and strong detoxification effect on superoxide radicals by the SOD/CAT-encapsulated hollow mesoporous silica nanoparticles demonstrate the general concept of implanting catalytic nanoreactors in biological cells with designed functions.
Purely Heterometallic Lanthanide(III) Macrocycles through Controlled Assembly of Disulfide Bonds for Dual Color Emission (2010)

Lanthanide complexes based on bis(amides) of diethylenetriaminepentaacetic acid with thiol functionalities are modified with 2,2'-dipyridyl disulfide to give activated complexes that can selectively react with thiol-functionalized complexes to form heterometallic lanthanide macrocycles. The preparation and full characterization of the polyaminocarboxylate ligands N,N''-bis[p-thiophenyl(aminocarbonyl)]diethylenetriamine-N,N',N''-triacetic acid (H(3)L(x)) and the activated N,N''-bis[p-(pyridyldithio)[phenyl(aminocarbonyl)]]diethylenetriamine-N,N',N''-triacetic acid (H(3)L(y)) and the complexes LaL(x), NdL(x), SmL(x), EuL(x), GdL(x), DyL(x), TbL(x), ErL(x), and YbL(x) are reported. The luminescence properties of the LnL(x) complexes emitting in the visible (where Ln = Dy(3+), Tb(3+), Eu(3+), and Sm(3+)) are examined by steady-state and time-resolved photoluminescence, and the triplet state energy level of GdL(x) was estimated to be 24 100 cm(-1) from the 0-0 band of the 77 K phosphorescence spectrum. Near-infrared emission was detected for the NdL(x), YbL(x), and ErL(x) complexes, demonstrating the versatility of the thiophenol chromophore. The assembly of purely heterometallic EuTbL(x)(2) macrocycles by reaction of EuL(x) with TbL(y) was followed by UV-vis absorption spectroscopy, monitoring the characteristic absorption peak of pyridyl-2-thione at 353 nm. Analysis of the solution by mass spectrometry reveals the formation of purely heterometallic macrocycle EuTbL(x)(2). This is in contrast with the results obtained by dynamic self-assembly under oxidative conditions, where we observe a statistical mixture of macrocyclic complexes of Eu(2)L(x)(2), Tb(2)L(x)(2), and EuTbL(x)(2). The EuTbL(x)(2) macrocycle displays dual color emission, incorporating the characteristic f-f transitions of Eu(3+) and Tb(3+). Investigation into the time-resolved photophysical properties of EuTbL(x)(2) reveals energy transfer from Tb(3+) to Eu(3+), facilitated by the different conformations of the macrocycle in solution.
Cutting Edge: Spontaneously Ig-Secreting B-1 Cells Violate the Accepted Paradigm for Expression of Differentiation-Associated Transcription Factors (2005)

B-1 cells spontaneously secrete natural Ig that acts as a primary line of defense against infection. A major shortfall in our understanding of this key process centers on the molecular mechanisms regulating natural Ab secretion by B-1 cells. Herein, we demonstrate that secreting B-1 cells use some aspects of the recently recognized plasmacytic differentiation program but deviate from it in important ways. Specifically, we show that key repressors of the plasmacytic program, B cell leukemia/lymphoma-6 and paired box gene 5, are reduced in spontaneously secreting B-1 B cells, as in stimulated differentiated B-2 cells. Surprisingly, we find that key promoters of the plasmacytic program, B lymphocyte inducer of maturation program 1 and X-box binding protein 1, are not up-regulated in secreting B-1 cells, in contrast to secreting B-2 cells. These data demonstrate that B-1 cells operate under a differentiation program that is unique and differs from the paradigm associated with Ig-secreting B-2 cells.
CD38 Triggers Cytotoxic Responses in Activated Human Natural Killer Cells (1999)

Receptors used by natural killer (NK) cells to mediate natural cytotoxicity are poorly defined, although it is now clear that a number of adhesion molecules can serve this function. CD38 transduces signals on T- and B-cell lines, and we asked whether it could trigger lytic and secretory responses in human NK cells. By using an anti-CD38 monoclonal antibody in reverse antibody-dependent cellular cytotoxicity experiments, it is shown that CD38 engagement triggers cytotoxic responses by activated NK cells, but not by cytotoxic T lymphocytes or fresh NK cells. Cross-linking with anti-CD38 F(ab')(2) caused activated NK cells to release granzymes and cytokines, but did not trigger an increase in intracellular Ca(2+). Fresh NK cells acquired CD38-dependent lytic function during activation with interleukin-2 (IL-2), and inhibitor studies suggested that IL-2 stimulated the de novo expression of proteins that act between CD38 and the lytic machinery in NK cells. The induction of proteins that link commonly expressed adhesion molecules to effector mechanisms could provide a paradigm for pathogen recognition by the innate immune system.
Development and Validation of the Sexist Attitudes Toward Women Scale (SATWS) (1980)

Although sexism is now defined as a major social problem, there have been very few empirical studies investigating its correlates and determinants. One primary reason for this is that there are no published sexism scales, and hence it is difficult to assess individual differences in sexism. This article describes the development and validation of a 40–item Sexist Attitudes Toward Women Scale (SATWS). On rational-intuitive grounds, it is hypothesized that sexism toward women has seven components and, accordingly, items were written to reflect these. It is suggested that scales measuring only one of these components (e.g., sex-role stereotype scales and women's liberation movement scales) lack content validity as measures of sexism. On empirical grounds it is argued that the SATW scale also has stronger construct validity as a measure of sexism toward women than other such scales. The SATW scale has high internal consistency reliability for both college students and nonstudent adults and the SATW scale scores are independent of social desirability scores. Relationships to age, sex, and education are presented.
Observation of inhibited spontaneous emission (1985)

The radiative decay of the cyclotron motion of a single electron is significantly inhibited when the electron is located within microwave cavity (formed by the electrodes of a Penning trap) rather than in free space. This is the first observation of such inhibited spontaneous emission and the first use of a promising new system for radiative physics. Implications for precision measurements are mentioned.
Graphene mediated domain formation in exchange coupled graphene/Co<sub>3</sub>O<sub>4</sub>(111)/Co(0001) trilayers (2013)

Graphene grown directly on Co3O4(111)/Co(0001) by molecular beam epitaxy exhibits extrinsic p-type doping, as demonstrated by photoemission and conductivity measurements. Trilayer heterostructures of graphene/Co3O4(111)/Co(0001) reveal an unconventional magneto-optical Kerr hysteresis with vanishing remanence for temperatures up to 400 K. Magnetic force microscopy measurements demonstrate that the vanishing remanence is due to a complex domain state, indicating substrate-induced graphene spin polarization. The domain formation of the Co magnetization is in strong contrast to the magnetic behavior of Co in Co/Co3O4 bilayers. This suggests that the Co3O4 interlayer mediates the variable Co magnetization and induced graphene spin polarization, with possible retroaction of graphene on the Co film.
Centrally acting emetics. 9. Hofmann and Emde degradation products of nuciferine (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCentrally acting emetics. 9. Hofmann and Emde degradation products of nuciferineJoseph G. Cannon, Plaston R. Khonje, and John Paul LongCite this: J. Med. Chem. 1975, 18, 1, 110–112Publication Date (Print):January 1, 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/jm00235a026https://doi.org/10.1021/jm00235a026research-articleACS PublicationsRequest reuse permissionsArticle Views207Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Repellent and Larvicidal Activity of the Essential Oil From Eucalyptus nitens Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae) (2017)

Dengue, chikungunya, and yellow fever are important vector-borne diseases transmitted by female mosquitoes when they feed on humans. The use of repellents based on natural products is an alternative for personal protection against these diseases. Application of chemicals with larvicidal activity is another strategy for controlling the mosquito population. The repellent and larvicidal activities of the essential oil from Eucalyptus nitens were tested against Aedes aegypti and Aedes albopictus, the main vectors of these arboviruses. The essential oil was extracted by hydrodistillation and then analyzed by gas chromatography-mass spectrometry. The main components of Eucalyptus nitens essential oil were found to be terpenes such as 1,8-cineole and p-cymene, followed by β-triketones and alkyl esters. The repellent activity of the essential oil against both species was significantly higher when compared with the main component, 1,8-cineole, alone. These results indicate that the repellent effect of E. nitens is not due only to the main component, 1,8-cineole, but also that other compounds may be responsible. Aedes aegypti was found to be more tolerant to the essential oil larvicidal effects than Ae. albopictus (Ae. aegypti LC50 = 52.83 ppm, Ae. albopictus LC 50 = 28.19 ppm). The repellent and larvicidal activity could be associated to the presence of cyclic β-triketones such as flavesone, leptospermone, and isoleptospermone.
Plasmid presence changes the relative levels of many host cell proteins and ribosome components in recombinant <i>Escherichia coli</i> (1991)

Relative levels of many individual proteins in Escherichia coli HB101 strains with 0, 37, 56, and 240 plasmids per chromosome were determined by computer image analysis of two-dimensional gel electrophoresis patterns. The plasmids investigated had very similar sequences except for small domains encoding the repressor of plasmid replication. At the intermediate plasmid copy number of 56, levels of several of the TCA cycle enzymes (oxoglutarate dehydrogenase complex, succinate thiokinase, and succinate dehydrogenase) as well as in aspartate transcarbamoylase increased. At a plasmid copy number of 240, higher amounts of PEP carboxylase as well as several of the heat shock proteins were observed. Furthermore, at high plasmid levels, significant decreases occurred in growth rate, pyruvate kinase I, pyruvate dehydrogenase complex, unadenylated glutamine synthetase, aspartate transcarbamoylase as well as in several of the proteins involved in translation. Decreases in ribosome content as well as in the free 30S and 50S ribosomal subunit pool fractions were also observed in separate analyses. These results indicate that recombinant DNA manipulations can cause major alterations in numerous host cell properties which could significantly influence cloned protein production or metabolic engineering endeavors.
Synthesis of beta carbon nitride nanosized crystal through mechanochemical reaction (2003)

Nanosized beta carbon nitride (β-C3N4), of grain size several tens of nanometres, has been synthesized by mechanochemical reaction processing. The low-cost synthetic method developed facilitates the novel and effective synthesis of nanosized crystalline β-C3N4 (a = 6.36 Å, c = 4.648 Å) powders. The graphite powders were first milled to a nanoscale state, then the nanosized graphite powders were milled in an atmosphere of NH3 gas. It was found that nanosized β-C3N4 was formed after high-energy ball milling under an NH3 atmosphere. After thermal annealing, the shape of the β-C3N4 changes from flake-like to sphere-like. The nanosized β-C3N4 formed was characterized by x-ray diffraction, Fourier transformation infrared spectroscopy, and transmission electron microscopy. A solid–gas reaction mechanism was proposed for the formation of nanosized β-C3N4 at room temperature induced by mechanochemical activation.
Alpha 2 beta 1 integrins from different cell types show different binding specificities. (1990)

Purified alpha 2 beta 1 integrin from human platelets was compared in its function and immunoreactivity to alpha 2 beta 1 from endothelial cells. Both alpha 2 beta 1 integrins bound to type I collagen-Sepharose and had indistinguishable immunoreactivities when analyzed by a panel of monoclonal and polyclonal alpha 2-specific antibodies. However, functional analysis using rechromatography of purified receptors on laminin and collagen-Sepharose showed that endothelial alpha 2 beta 1 was able to bind to laminin, whereas its counterpart from platelets did not. Moreover, a receptor binding assay indicated that, in contrast to platelets, endothelial cells might also use alpha 2 beta 1 to bind to fibronectin. These results suggest that the alpha 2 beta 1 binding specificity may be modulated by cell-type specific factors.