gebhart/patrepeval huggingface dataset:
Oligosaccharides Derived from Bovine Articular Cartilage Keratan Sulfates after Keratanase II Digestion: Implications for Keratan Sulfate Structural Fingerprinting (1994)

Keratan sulfate chains were isolated from bovine articular cartilage (6-8-year-old animals) and digested with keratanase II, an endo-beta-N-acetylglucosaminidase [Nakazawa, K., Ito, M., Yamagata, T., & Suzuki, S. (1989) in Keratan Sulphate: Chemistry, Biology and Chemical Pathology (Greiling, H., & Scott, J. E., Eds.) pp 99-110, The Biochemical Society, London]. Twenty-five borohydride-reduced oligosaccharides were purified chromatographically and characterized by one- and two-dimensional NMR spectroscopy. From the structures of these oligosaccharides the following conclusions can be drawn about the mode of action of keratanase II: (1) The enzyme cleaves the beta (1-->3)-glycosidic bond between 6-O-sulfated N-acetyl-glucosamine and galactose, the major products being mono- and disulfated disaccharides. (2) Larger oligosaccharides containing keratanase II susceptible bonds are produced which are resistant to further degradation, e.g., tetrasaccharides from the sulfated poly(N-acetyllactosamine) repeat sequence, fucose-containing penta- and hexasaccharides, and hexa- and heptasaccharides from the linkage region. (3) The enzyme cleaves the beta (1-->3)-glycosidic bond of a fucosylated 6-O-sulfated N-acetylglucosamine. (4) Sialic acid-containing capping fragments are always recovered as pentasaccharides, despite the presence of an apparently susceptible bond. Two new elements of skeletal keratan sulfate structure, namely, the highly sulfated cap NeuAc alpha 2-3Gal(6S) beta 1-4GlcNAc (6S) beta 1-3Gal(6S) beta 1-4GlcNAc (6S)-ol and the difucosylated sequence Gal beta 1-4(Fuc alpha 1-3)GlcNAc(6S)beta 1-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc(6S)-ol, have been identified. A structural model for articular cartilage keratan sulfate is proposed. The potential of the enzyme keratanase II for the structural fingerprinting of subnanogram quantities both of keratan sulfates and of sulfated oligosaccharide selectin ligands is discussed.
Billing service based on TINA concepts for the next generation network (2002)

Service and network resources used on the next generation network (NGN) are billable. This paper presents the use of the TINA retailer and accounting management architecture as the basis for usage accounting in the NGN. Three computational objects, namely the accountable object, the metering manager and the accounting policy manager, are used. A CORBA-based distributed processing environment (DPE) enables the TINA components to be deployed in a non-TINA NGN environment. Service components and computational objects used in the TINA accounting management are described. The implementation of the billing service, using TINA concepts is presented.
New One-Pot Synthesis of (<i>E</i>)-β-Aryl Vinyl Halides from Styrenes (2009)

A new, efficient protocol for the highly stereoselective one-pot synthesis of (E)-beta-aryl vinyl iodides and (E)-beta-aryl vinyl bromides from styrenes based on sequential ruthenium-catalyzed silylative coupling-N-halosuccinimide-mediated halodesilylation reactions is reported.
A fast algorithm for computing a histogram on reconfigurable mesh (1995)

The reconfigurable mesh captures salient features from a variety of sources, including the content addressable array parallel processor, the CHiP, the polymorphic-torus network and the bus automaton. It consists of an array of processors interconnected by a reconfigurable bus system. The bus system can be used to dynamically obtain various interconnection patterns between the processors. In this paper, we present a fast algorithm for computing the histogram of an N/spl times/N image with h grey levels in O(min{/spl radic/h+log*(N/h),N}) time on an N/spl times/N reconfigurable mesh assuming each PE has a constant amount of local memory. This algorithm runs on the PARBUS and MRN/LRN models. In addition, histogram modification can be performed in O(/spl radic/h) time on the same model. A variant of out algorithm runs in O(min{/spl radic/h+log log(N/h),N}) time on an N/spl times/N RMESH in which each PE has constant storage. This result improves the known time and memory bounds for histogramming on the RMESH model.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Accessory cell-T lymphocyte interactions. Antigen-dependent and -independent clustering. (1986)

Previous work documented the capacity of dendritic cells (DC) to stimulate primary immune responses and to physically cluster with the responding lymphocytes. Rapid cell-cell aggregation assays were used here to study the interaction of DC and other types of APC with T lymphocytes. Graded doses of APC were sedimented with T cells that had been primed to alloantigens, soluble proteins, or lectin, and then labeled with carboxyfluorescein diacetate. The number of clustered T cells was measured after 10 min at 4 or 37 degrees C. At 4 degrees, binding was antigen-dependent and included greater than 50% of the added T cells. Clustering was mediated by all types of APC tested, including DC, macrophages, B lymphocytes, and fresh Langerhans cells, although DC were the most effective. Specificity was evident in the findings that alloreactive T lymphoblasts bound to allogeneic but not syngeneic APC; KLH- and OVA-reactive T cells bound to syngeneic APC in the presence of specific protein: and Con A blasts needed lectin to cluster. A 30 min pretreatment with chloroquine, a drug known to inhibit APC activity, markedly blocked the specific binding of alloreactive and protein-specific T blasts at 4 degrees C. Since Lyt-2- alloreactive blasts should specifically recognize Ia, presentation of Ia seems to be altered by chloroquine. Binding assays at 37 degrees C gave similar results to those performed at 4 degrees C, with one exception. When DC were used as APC, striking antigen-independent clustering occurred. DC could efficiently cluster primed T cells in the absence of alloantigen, soluble protein, or lectin. We suggest that antigen-independent binding contributes to the distinctive capacity of DC to prime T cells in the afferent limb of the immune response, whereas antigen-dependent binding between other APC and sensitized lymphocytes is critical in the efferent limb.
[Kinetic, radiographic, and histologic demonstration of the curing of congenital osteopetrosis in rats]. (1975)

In the "op" rat congenital osteopetrosis is a lethal condition. The management of this disease can be achieved by a single injection of a marrow cell suspension from a normal donor or by temporary parabiosis with a normal Rat, the latter procedure being less efficient than the former according to kinetic, roentgenographical and histological examinations.
Effect of heat treatment on the performance of tryptose-sulfite-cycloserine agar for enumeration of Clostridium perfringens (1979)

Dissolving dehydrated tryptose-sulfite-cycloserine agar by only boiling or microwaving was found to inhibit Clostridium perfringens colony development in pour plates when compared with C. perfringens recovery in tryptose-sulfite-cycloserine agar prepared by autoclaving.
[Use of biomaterials for preventive and restorative purposes]. (1992)

At the Dept. of Maxillofacial Surgery, Semmelweis University of Medicine many biomaterials have been used in the last 10 year. Author deals with only three materials, such as solid aluminiumoxyde ceramics, titanium screws and HTR Polymers. The Al2O3 ceramics can be used for the reconstruction of the lower jaws, the condyle and the coronoid process of the mandible as well as for dental implants and for the improvement of the facial contour. This material proved to be the most suitable for the reconstruction of the mandible and TM joint. The titanium screw implant (Flexi-root system) has been used in many hundreds of patients with some 90% success rate. The HTR Polymer has been used in the periodontal surgery, in small and medium size cyst operations and sinus lift procedures. The technique of sinus lift has also been discussed.
High Resolution Mapping of the Cardiac Transmural Proteome Using Reverse Phase Protein Microarrays (2011)

The expression level of proteins governing the electrical excitability of and conduction within ventricular myocardium are known to vary as a function of distance through the heart wall. The expression patterns of a subset of these proteins are altered in disease. Precise measurement of such patterns is therefore essential to understanding structure-function relationships within the heart in health and disease. Here, we report a new experimental approach using reverse-phase protein microarrays to map the left ventricular transmural proteome. This approach can yield submillimeter spatial resolution, and when coupled with the method of array microenvironment normalization, reduces nonbiological components of variability to ∼10% of overall study variability. In addition, the experimental design provides sufficient statistical power to detect small, yet potentially biologically significant expression changes on the order of 1.1-fold. The usefulness of this technique is demonstrated by mapping the transmural expression of Serca2a in the left ventricle of 12 canine hearts, each in one of three states: normal, dyssynchronous heart failure, and dyssynchronous heart failure followed by cardiac resynchronization therapy. We confirm the existence of a 40% transmural gradient (epi>endo) of Serca2a, and demonstrate the ability of this technique to yield highly significant transmural expression differences within each individual heart.
MARTe: A Multiplatform Real-Time Framework (2010)

Development of real-time applications is usually associated with nonportable code targeted at specific real-time operating systems. The boundary between hardware drivers, system services, and user code is commonly not well defined, making the development in the target host significantly difficult. The Multithreaded Application Real-Time executor (MARTe) is a framework built over a multiplatform library that allows the execution of the same code in different operating systems. The framework provides the high-level interfaces with hardware, external configuration programs, and user interfaces, assuring at the same time hard real-time performances. End-users of the framework are required to define and implement algorithms inside a well-defined block of software, named Generic Application Module (GAM), that is executed by the real-time scheduler. Each GAM is reconfigurable with a set of predefined configuration meta-parameters and interchanges information using a set of data pipes that are provided as inputs and required as output. Using these connections, different GAMs can be chained either in series or parallel. GAMs can be developed and debugged in a non-real-time system and, only once the robustness of the code and correctness of the algorithm are verified, deployed to the real-time system. The software also supplies a large set of utilities that greatly ease the interaction and debugging of a running system. Among the most useful are a highly efficient real-time logger, HTTP introspection of real-time objects, and HTTP remote configuration. MARTe is currently being used to successfully drive the plasma vertical stabilization controller on the largest magnetic confinement fusion device in the world, with a control loop cycle of 50 ?s and a jitter under 1 ?s. In this particular project, MARTe is used with the Real-Time Application Interface (RTAI)/Linux operating system exploiting the new ?86 multicore processors technology.
Fructosamine as a screening‐test for gestational diabetes mellitus: a reappraisal (1991)

Fructosamine, glycosylated hemoglobin (HbA1c) and serum total proteins were measured in normal nondiabetic pregnant women (n = 170) at three stages of pregnancy (14-18, 24-28, and 32-40 weeks of gestation). No significant correlation was found between fructosamine and either HbA1c or total plasma proteins. Only early in pregnancy (less than 20 weeks of gestation) was a correlation found between fructosamine and fasting blood glucose (r = 0.40, P less than 0.05). There was also no correlation between either tests (i.e. fructosamine and HbA1c) and fetal birthweight. The value of fructosamine measurement in the detection of diabetes in pregnancy was further tested in a group of high-risk patients (n = 98) for developing carbohydrate intolerance. It is concluded that fructosamine has limited value as a screening test for gestational diabetes mellitus, particularly for the mild form of the glucose intolerance.
Dual-cavity doubly resonant optical parametric oscillators: demonstration of pulsed single-mode operation (2000)

The operating points of pulsed dual-cavity doubly resonant optical parametric oscillators have been investigated, taking into account the influence of the optical dispersion. A diagram is proposed to determine the spectral separation of doubly resonant positions for any optical lengths of both cavities. From the analysis of the distribution of doubly resonant coincidences, original conditions for stable single-mode operation are specified. This approach is validated by use of a type II phase-matched β-barium borate crystal. Frequency stability and tuning characteristics are also reported. To our best knowledge, this is the first demonstration of single-mode operation that uses a dual-cavity doubly resonant optical parametric oscillator in the nanosecond pulsed regime.
Workplace surveillance: an overview (2010)

This article attempts to review the proliferation of research findings about surveillance in the workplace and the issues surrounding it. It establishes a number of points of departure when considering the issue of workplace surveillance, before reviewing some of the more critical issues. First, it establishes that organizations and surveillance go hand in hand; and that workplace surveillance can take social and technological forms. Personal data gathering, Internet and email monitoring, location tracking, biometrics and covert surveillance are all areas of development. There is also evidence that groups of employees are appropriating information and communication technologies to stare back at their employers, exposing unsavoury practices and organizing collectively, prompting new thinking about resistance. Organizations watch employees primarily to protect their assets, although the nature and intensity of surveillance says much about how a company views its employees. Workplace surveillance has consequences for employees, affecting employee well-being, work culture, productivity, creativity and motivation. If no alternative can be found, managerial attention to task design, supervisory processes, employees’ expectations about monitoring, and an appraisal of the company's operating environment can mediate its downsides. It is argued that in many ways the normality of workplace surveillance, and the prevalence of arguments about how to ‘do it better’, make it difficult to radicalize. As part of what is seen as ‘good’ management practice, it can confer benefits on the employee if conducted in a humane, balanced way, and is considered on a case-by-case–organization-by-organization–basis. However, the introduction of broader debates around information use, rights, power and social structure highlights how surveillance in the workplace may serve to perpetuate existing inequalities and create new ones.
The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias. (1986)

Genomic and cDNA clones for the human nerve growth factor receptor have been used in conjunction with somatic cell hybrid analysis and in situ hybridization to localize the nerve growth factor receptor locus to human chromosome region 17q12-q22. Additionally, part, if not all, of the nerve growth factor receptor locus is present on the translocated portion of 17q (17q21-qter) from a poorly differentiated acute leukemia in which the chromosome 17 breakpoint was indistinguishable cytogenetically from the 17 breakpoint observed in the t(15;17)(q22;q21) translocation associated with acute promyelocytic leukemia. Thus the nerve growth factor receptor locus may be closely distal to the acute promyelocytic leukemia-associated chromosome 17 breakpoint at 17q21.
Experimental Studies on Peripheral Nerve Repair: a possibility of application to cure nerve complication of Hansen's disease. (1999)

[in Japanese]
The effect of the daily intake of inulin on fasting lipid, insulin and glucose concentrations in middle-aged men and women (1999)

The present study was carried out to examine the effect of the daily intake of 10 g inulin on fasting blood lipid, glucose and insulin levels in healthy middle-aged men and women with moderately raised total plasma cholesterol (TC) and triacylglycerol (TAG) levels. This study was a double-blind randomized placebo-controlled parallel study in which fifty-four middle-aged subjects received either inulin or placebo for a period of 8 weeks. Fasting blood samples were collected before the supplementation period (baseline samples 1 and 2, separated by 1 week) and at weeks 4 and 8, with a follow-up at week 12. Compared with baseline values, insulin concentrations were significantly lower at 4 weeks (P < 0.01) in the inulin group. There was a trend for TAG values, compared with baseline, to be lower in the inulin group at 8 weeks (P < 0.08) returning to baseline concentrations at week 12. On comparison of the inulin and placebo groups, the fasting TAG responses over the 8-week test period were shown to be significantly different (P < 0.05, repeated measures ANOVA), which was largely due to lower plasma TAG levels in the inulin group at week 8. The percentage change in TAG levels in the inulin group during the 8-week study was shown to correlate with the initial TAG level of the subjects (rs -0.499, P = 0.004). We therefore conclude that the daily addition of 10 g inulin to the diet significantly reduced fasting insulin concentrations during the 8-week test period and resulted in lower plasma TAG levels, particularly in subjects in whom fasting TAG levels were greater than 1.5 mmol/l. These data support findings from animal studies that fructans influence the formation and/or degradation of TAG-rich lipoprotein particles, and the insulin data are also consistent with recent studies showing attenuation of insulin levels in fructan-treated rats.
The Modifications of the Carbide, Fe<sub>2</sub>C; Their Properties and Identification (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Modifications of the Carbide, Fe2C; Their Properties and IdentificationL. J. E. Hofer, E. M. Cohn, and W. C. PeeblesCite this: J. Am. Chem. Soc. 1949, 71, 1, 189–195Publication Date (Print):January 1, 1949Publication History Published online1 May 2002Published inissue 1 January 1949https://pubs.acs.org/doi/10.1021/ja01169a048https://doi.org/10.1021/ja01169a048research-articleACS PublicationsRequest reuse permissionsArticle Views725Altmetric-Citations95LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Beginning JSP, JSF and Tomcat: Java Web Development (2012)

Start building Javabased web applications now, even if youre a complete newcomer to Java. Comprehensive and exampledriven, Beginning JSP, JSF, and Tomcat: Java Web Development, Second Edition is all you need to develop dynamic Java-based web applications using JSP, connect to databases with JSF, and put them into action using the worlds most popular open source Java web server, Apache Tomcat. A comprehensive introduction to JavaServer Pages (JSP), JavaServer Faces (JSF), and the Apache Tomcat web application server Key concepts made easy to grasp by numerous working examples and a walkthrough of the development of a complete e-commerce project Written for professionals by a practicing Java web application professional and expert
Network Virtualization from a Signaling Perspective (2009)

The use of network virtualization promises additional flexibility and opens up many opportunities for deploying future network architectures. But the increased flexibility creates additional costs with respect to management and control as well as new issues that need to be addressed. In this paper, we describe a framework that allows for dynamic setup of virtual networks and we point out required mechanisms, interfaces, and protocols. Additionally, we take into account runtime aspects by examining control interfaces and signaling protocols necessary for the management of virtual networks and the attachment of end users.
Targeting HSP70: The second potentially druggable heat shock protein and molecular chaperone? (2010)

The HSF1-mediated stress response pathway is steadily gaining momentum as a critical source of targets for cancer therapy. Key mediators of this pathway include molecular chaperones such as heat shock protein (HSP) 90. There has been considerable progress in targeting HSP90 and the preclinical efficacy and signs of early clinical activity of HSP90 inhibitors have provided proof-of-concept for targeting this group of proteins. The HSP70 family of molecular chaperones are also key mediators of the HSF-1-stress response pathway and have multiple additional roles in protein folding, trafficking and degradation, as well as regulating apoptosis. Genetic and biochemical studies have supported the discovery of HSP70 inhibitors which have the potential for use as single agents or in combination to enhance the effects of classical chemotherapeutic or molecularly targeted agents including HSP90 inhibitors. Here we provide a perspective on the progress made so far in designing agents which target the HSP70 family.
Diatomaceous Earth (1930)

Journal Article Diatomaceous Earth Get access Diatomaceous Earth. By Robert Calvebt. The Chemical Catalog Co., Inc., New York City, N. Y. 1930. Price $5.00. Robert Calvebt Robert Calvebt Search for other works by this author on: Oxford Academic Google Scholar Journal of Association of Official Agricultural Chemists, Volume 13, Issue 2, 15 May 1930, Page 294, https://doi.org/10.1093/jaoac/13.2.294 Published: 24 February 2020