gebhart/patrepeval huggingface dataset:
Retrieval of paintings using principal color information (1996)

This paper describes a method for indexing and retrieving color paintings, in which information about "principal" colors is used as key for retrieval. Several principal color regions are extracted by evaluating each region obtained by image segmentation in terms of likeliness for forming principal color regions and background color regions. Retrieval of paintings is done by just specifying principal colors used and their spatial relationships, or by specifying "impression word" that indicate the impression of the paintings. Although the method is simple, it must be useful for managing and retrieving pictures in image database system.
Quicker response results in better SpO2 control – a comparison of 3 FiO2-titration strategies in ventilated preterm infants (2015)

All three approaches provided excellent control of SpO2 in infants with infrequent desaturations, significantly better than typical routine care. In hard to manage infants with frequent desaturations, faster response appeared to result in better control. The potential of automating the tedious error prone FiO2 adjustment offers significant promise. If manual titration of FiO2 is to remain the usual method of care, additional studies are needed to identify optimal approaches.
A Novel Transmit Power Allocation Algorithm Combined with Dynamic Channel Allocation in Reuse Partitioning-based OFDMA/FDD System (2006)

This paper introduces a reuse partitioning-based dynamic channel allocation algorithm that guarantees quality of service (QoS) by considering fairness among mobile stations in an OFDMA/FDD system. To improve the SINR values for users around the cell edge and increase the overall system throughput compared with the conventional OFDMA/FDD system of frequency reuse factor (FRF) 1, an effective transmit power allocation algorithm is also combined with the proposed dynamic channel allocation to adjust the transmit power per user according to the average received SINR value. Simulation results show that the proposed DCA algorithm increases the sector throughput by about 25% when compared with the conventional case that do not apply the proposed DCA algorithm. When the proposed transmit power allocation algorithm is combined with the proposed DCA algorithm, a further increase in the sector throughput of about 6% is achieved than when using just the proposed DCA algorithm.
Regulation of iron metabolism in HepG2 cells: A possible role for cytokines in the hepatic deposition of iron (1993)

In chronic inflammation it is reported that serum iron is depleted and hepatic iron is increased because of reticuloendothelial system iron blockade. However, recent studies indicate that hepatic parenchymal cells increase the uptake of transferrin-bound iron after in vivo stimulation with bacterial lipopolysaccharide, suggesting that endotoxemia itself or lipopolysaccharide-induced production of inflammation-related cytokines may also be responsible for this phenomenon. In this study the actions of inflammation-related cytokines on the synthesis of iron-binding proteins (transferrin and ferritin) and transferrin receptor and the uptake of transferrin-bound iron were investigated in a human hepatoblastoma cell line, HepG2, which is the most commonly used cell line for examining the regulation of hepatic protein synthesis by cytokines. The cells were exposed to interleukin-1 beta, interleukin-6 or tumor necrosis factor-alpha separately for 24 hr. In each cytokine treatment group, the level of transferrin, which is secreted into the conditioned medium, was found to be decreased compared with that of untreated cells. On the other hand, the biosynthesis of ferritin was markedly elevated after the same treatment. This increase in ferritin by cytokine treatment was diminished when deferoxamine was used concomitantly to deplete intracellular chelatable iron. After stimulation with interleukin-1 beta, interleukin-6 or tumor necrosis factor-alpha, 59Fe-labeled transferrin uptake into the cells was increased by 36%, 48%, or 18%, respectively, and this uptake was inhibited by the addition of excess unlabeled transferrin. A binding study with 125I-labeled diferric transferrin revealed that the three cytokines increased the number of transferrin receptors on the cell surface by 1.15-fold to 1.35-fold.(ABSTRACT TRUNCATED AT 250 WORDS)
Matrix Variate RBM Model with Gaussian Distributions (2016)

Restricted Boltzmann Machine (RBM) is a particular type of random neural network models modeling vector data based on the assumption of Bernoulli distribution. For multi-dimensional and non-binary data, it is necessary to vectorize and discretize the information in order to apply the conventional RBM. It is well-known that vectorization would destroy internal structure of data, and the binary units will limit the applying performance due to fickle real data. To address the issue, this paper proposes a Matrix variate Gaussian Restricted Boltzmann Machine (MVGRBM) model for matrix data whose entries follow Gaussian distributions. Compared with some other RBM algorithm, MVGRBM can model real value data better and it has good performance in image classification.
Normal self proteins as targets for tumour specific cytotoxic T lymphocytes (CTL) (1996)

Many tumour cells express high levels of proteins which are present in normal cells at lower levels. Such proteins might be targets for immunotherapy if lymphocytes with specificity for these proteins are present in the repertoire and can discriminate between cells expressing high or low levels of the target protein. The first step in exploring the possibility of targeting immunotherapy to normal self proteins is therefore to determine whether lymphocytes specific for molecules overexpressed in tumours exist and can be activated to recognize specifically cells expressing high levels of the proteins. It was possible to stimulate murine cyclin D1 or mdm2 specific cytotoxic T lymphocytes (CTL) by in vivo priming of mice with recombinant vaccinia virus expressing the proteins. The in vitro conditions used for restimulation of in vivo primed CTL were found to have a profound effect on the magnitude of the CTL response observed in vitro. In addition, in vitro priming of CTL from naïve spleens with peptide pulsed dendritic cells identified a mdm2 derived peptide, mdp441, which could stimulate CTL capable of recognising endogenously processed mdm2. These peptide specific CTL were of high avidity in contrast to most of the peptide specific CTL stimulated with other self peptides. The mdp441 peptide was not recognised by mdm2 specific CTL generated by in vivo immunisation with mdm2 protein. The results show that tolerance to self proteins is not absolute and that it is possible to stimulate CTL to recognize endogenously processed self protein either by in vivo immunisation with recombinant vaccinia virus expressing the self protein or by in vitro priming of naive responder cells with peptide pulsed antigen presenting cells. These results have implications for immunotherapy of human cancers.
Recovery of acoustic impedance from reflection seismograms (1982)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1982Recovery of acoustic impedance from reflection seismogramsAuthors: D. W. OldenburgT. ScheuerS. LevyD. W. OldenburgUniv. of British Columbia, T. ScheuerAmoco Production Co., and S. LevyUniv. of British Columbia, Canadahttps://doi.org/10.1190/1.1826890 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1826890FiguresReferencesRelatedDetailsCited BySeismic sparse-layer reflectivity inversion using basis pursuit decompositionRui Zhang and John Castagna22 December 2011 | GEOPHYSICS, Vol. 76, No. 6 SEG Technical Program Expanded Abstracts 1982ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1982 Pages: 520 publication data© 1982 Copyright © 1982 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 24 Mar 2005 CITATION INFORMATION D. W. Oldenburg, T. Scheuer, and S. Levy, (1982), "Recovery of acoustic impedance from reflection seismograms," SEG Technical Program Expanded Abstracts : 202-204. https://doi.org/10.1190/1.1826890 Plain-Language Summary PDF DownloadLoading ...
Pitfalls of use of lipemic serum with the Technicon SMAC and Du Pont aca. (1978)

Journal Article Pitfalls of use of lipemic serum with the Technicon SMAC and Du Pont aca. Get access F R Hindriks, F R Hindriks Search for other works by this author on: Oxford Academic Google Scholar A Groen A Groen Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 24, Issue 11, 1 November 1978, Pages 2062–2063, https://doi.org/10.1093/clinchem/24.11.2062 Published: 01 November 1978
Protective effect of beta carotene against colon tumors in mice. (1987)

The effect of dietary beta carotene on colon carcinogenesis\nInduced by 1,2-dimethylhydrazine «DMH) CAS: 540-73-81\nwas studied in female inbred Swiss Webster (ICR) mice. At age\n10 weeks and continuing throughout the experiment, mice received\ndiets consisting mainly of natural foods (laboratory chow)\nand containing 2 or 22 mg p-carotene/kg. At age 15 weeks they\nreceived 7 weekly sc injections of DMH (total dose: 196 mg\nDMH-diHCI/kg body wt). When autopsied 31 weeks after the first\nDMH injection, the incidence (percent of mice with tumors) and\nmultiplicity (number of tumors/tumor-bearing mouse) of colon\ntumors were reduced by half in the mice supplemented with beta carotene.\nThere was a much greater decrease in adenocarcinomas\nthan in adenomas. Mice observed for 13 additional weeks revealed\nthat the mortality rate, due largely or wholly to colon cancer, was\nonly about half in supplemented mice. Mice sacrificed 12 weeks\nafter the first dose of DMH (Le., well before tumors appeared)\nshowed mild colon mucosal hyperplasia. p-Carotene supplementation,\nhowever, did not alter this, Indicating that the protective effect\nagainst colon cancer may have occurred at a late stage of\ncarcinogenesis.
CHEMICAL INTERCONVERSION OF TRYPTOPHAN AND <i>N</i>′-FORMYLKYNURENINE (1979)

Abstract A novel reaction to convert 3-alkyl-2-amino-3H-indol-3-ol to 3-alkylindole is described. The yield was 60–80% for four 2-amino-3H-indol-3-ols examined. With aqueous sodium borohydride, 3-alkyl-2-amino-3H-indol-3-ol was reduced and deaminated predominantly to the corresponding indolin-3-ol, which was then dehydrated to 3-alkylindole in acidic media. Eventually a reaction cycle to interconvert tryptophan and N′-formylkynurenine was established.
25 Gbit/s transmission over 500 m multimode fibre using 850 nm VCSEL with integrated mode filter (2012)

An integrated mode filter in the form of a shallow surface relief was used to reduce the spectral width of a high-speed 850 nm vertical-cavity surface-emitting laser (VCSEL). The mode filter reduced the RMS spectral width from 0.9 to 0.3 nm for a VCSEL with an oxide aperture as large as 5 µm. Because of reduced effects of chromatic and modal fibre dispersion, the mode filter significantly increases the maximum error-free (bit error rate<10−12) transmission distance, enabling transmission at 25 Gbit/s over 500 m of multimode OM3+ fibre.
Morphological Features Pertinent to Interventional Closure of Patent Oval Foramen (2003)

Despite the growing trend of device closure for patent ovale foramens (PFO), the morphology of these lesions is much neglected. A better understanding of the morphological aspects is needed for developing lesion-specific devices. We reviewed ten heart specimens and distinguished two forms of PFO: valve competent and valve incompetent. In the valve-competent form, the thin valve of the oval foramen adequately overlaps the firmer muscular rim of the foramen, leaving a crevice-like aperture sandwiched between the two structures. In contrast, the valve-incompetent form results from aneurysmal ballooning of the valve, or stretching of the muscular rim, creating an interatrial communication in a previously competent flap valve. Distinguishing between the two forms can help in designing and selecting the most appropriate device for implantation.
A mobility management protocol for IP-based cellular networks (2002)

Mobile IP is an IETF RFC that supports transparent host migration on the Internet. In the transition to IP-based cellular networks, it is widely agreed that Mobile IP provides an elegant solution for inter-domain, or macro- mobility management, but lacks critical aspects of mobility management needed within cellular networks. The shortcomings have led to the recent emergence of micro- mobility management protocols. This paper presents an IP- based mobility management protocol, µ-Mobile IP, based on two enhancements, proactive handoff and paging support, to an Internet Draft proposal Regional Registrations. A signaling cost analysis is used to justify the need for such enhancements. We show through simulations the protocol's suitability for supporting real-time communications.
Novel Putative Galactose Operon Involving Lacto-<i>N</i>-Biose Phosphorylase in<i>Bifidobacterium longum</i> (2005)

A lacto-N-biose phosphorylase (LNBP) was purified from the cell extract of Bifidobacterium bifidum. Its N-terminal and internal amino acid sequences were homologous with those of the hypothetical protein of Bifidobacterium longum NCC2705 encoded by the BL1641 gene. The homologous gene of the type strain B. longum JCM1217, lnpA, was expressed in Escherichia coli to confirm that it encoded LNBP. No significant identity was found with any proteins with known function, indicating that LNBP should be classified in a new family. The lnpA gene is located in a novel putative operon for galactose metabolism that does not contain a galactokinase gene. The operon seems to be involved in intestinal colonization by bifidobacteria mediated by metabolism of mucin sugars. In addition, it may also resolve the question of the nature of the bifidus factor in human milk as the lacto-N-biose structure found in milk oligosaccharides.
gp63 in Stable Cationic Liposomes Confers Sustained Vaccine Immunity to Susceptible BALB/c Mice Infected with<i>Leishmania donovani</i> (2008)

Visceral leishmaniasis is deadly if not treated, and development of a vaccine with long-term immunity remains a challenge. In this study, we showed that cationic distearoyl phosphatidylcholine (DSPC) liposomes, when used as vaccine adjuvant with the immunodominant 63-kDa glycoprotein (gp63) of Leishmania donovani promastigotes, induced significant protection against progressive visceral leishmaniasis in susceptible BALB/c mice. gp63 used without adjuvant elicited partial protection but in association with liposomes exhibited marked resistance in both the livers and spleens of the mice challenged 10 days after the last vaccination. The protective efficacy of liposomal gp63 vaccination was dose dependent, with 2.5 mug of protein showing optimal protection. The immunity conferred by this vaccine formulation was durable, as mice challenged 12 weeks after immunization were still protected, and the infection was controlled for at least 3 months postchallenge. Production of gamma interferon (IFN-gamma) and interleukin-4 (IL-4) by splenic T cells, and of serum immunoglobulin G1 (IgG1) and IgG2a following immunization, suggested that a mixed Th1/Th2 response had been induced following immunization. However, control of disease progression and parasitic burden in mice vaccinated with gp63 in cationic DSPC liposomes was associated with enhancement of antigen-specific IFN-gamma and downregulation of IL-4, demonstrating a Th1 bias. Long-term immunity elicited by this vaccine corresponded to, in addition to the presence of antigen-specific Th1, CD8+ T-cell responses. Our results demonstrated that stable cationic liposomes containing gp63 acted as a potent adjuvant for protein antigen to induce long-term protection against L. donovani that represents an alternative to DNA vaccination.
Sorption of trace metals by humic materials in soils and natural waters (1986)

Trace metal sorption by coagulated humic acid and peat materials can be described macroscopically either as a complexation or a cation exchange phenomenon. Model equilibrium constants or selectivity coefficients for trace metal sorption by H‐form humic materials are special cases of two general models which do not depend on the sorption mechanism. Sorption mechanisms can be elucidated by spectroscopic techniques, both optical and magnetic resonance, but no information about mechanisms can be inferred from equilbrium constants.
Short Notices (1972)

Journal Article Short Notices Get access A. E. MUSSON A. E. MUSSON University of Manchester Search for other works by this author on: Oxford Academic Google Scholar The English Historical Review, Volume LXXXVII, Issue CCCXLV, October 1972, Pages 880-a–880, https://doi.org/10.1093/ehr/LXXXVII.CCCXLV.880-a Published: 01 October 1972
A framework for self-healing software systems (2013)

I present an approach to avoid functional failures at runtime in component-based application systems. The approach exploits the intrinsic redundancy of components to find workarounds as alternative sequences of operations to avoid a failure. A first Java prototype is presented, and an evaluation plan, as some preliminary results, are discussed.
SOME REACTIONS OF DELTA KETONIC NITRILES (1925)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSOME REACTIONS OF DELTA KETONIC NITRILESCharles F. H. AllenCite this: J. Am. Chem. Soc. 1925, 47, 6, 1733–1741Publication Date (Print):June 1, 1925Publication History Published online1 May 2002Published inissue 1 June 1925https://pubs.acs.org/doi/10.1021/ja01683a037https://doi.org/10.1021/ja01683a037research-articleACS PublicationsRequest reuse permissionsArticle Views38Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Growth phenotypes and biosafety profiles in poliovirus‐receptor transgenic mice of recombinant oncolytic polio/human rhinoviruses (2007)

The use of oncolytic recombinant polioviruses has an important therapeutic potential in the treatment of human gliomas. This study was carried out to assess parameters of the utility of the oncolytic poliovirus/human rhinovirus type 2 chimeras (PV/HRV2). The prototype PV/HRV2 chimera was constructed containing the complete genome of wild-type PV type 1 (Mahoney) [PV1(M)] in which the cognate IRES was replaced with that of HRV2 [called PV1(RIPO)]. A derivative of PV1(RIPO) is PV1(RIPOS) in which the capsid coding region (P1) was replaced with the capsid-coding region of the PV type 1 (Sabin) [PV1(S)] vaccine strain. In addition, a third PV/HRV2 chimera was constructed containing the complete genome of PV1(S) in which the cognate IRES was replaced with that of HRV2 [termed PVS(RIPO)]. To analyze the growth phenotypes of PV/HRV2 recombinants [PV1(RIPO), PV1(RIPOS), PVS(RIPO)], one-step growth experiments were performed in four human cell lines at three different temperatures. To address the safety profile, PVS(RIPO) was injected into the brain of CD155 tg mice at the dose 10(7) PFU. Then, clinical signs, persistence of the virus in the CNS and genetic stability of PVS(RIPO) replicating in the CNS were evaluated. The data obtained in the present study suggest (i) a correlation between temperature-sensitive (ts) phenotype in both neuronal and non-neuronal cell lines and neuroattenuation in experimental animals, (ii) that PVS (RIPO) is genetically stable on replication in the CNS of poliovirus-susceptible mice. These findings highlight the safety of intracerebral inoculation of PVS(RIPO) for the treatment of human glioma.
Induction of calcium flux across the rat mast cell membrane by bridging IgE receptors. (1979)

Rabbit antibody against IgE receptors or its F(ab')2 fragments induced an increase of 45Ca uptake into normal mast cells, and this process was accompanied by histamine release. Evidence was obtained that a substantial portion of 45Ca uptake was due to movement of calcium across the cell membrane. Neither 45Ca uptake nor histamine release was induced by Fab' monomer fragments of the antireceptor antibody. However, bridging of receptor-bound Fab' fragments by antirabbit IgG or bridging of receptor-bound IgE by anti-IgE induced an increase in 45Ca uptake. The results collectively indicate that crosslinking IgE receptors increases the membrane permeability of the mast cells toward calcium.
Differential distribution of AT1 and AT2 angiotensin II receptor subtypes in the rat brain during development. (1991)

Angiotensin II (AII) receptor subtypes were analyzed in the brains of adult and 2-week-old rats by in vitro autoradiography with 125I-labeled [Sar1,Ile8]AII and competition studies with three AII antagonists: the nonpeptide antagonist, DuP 753, which is specific for AT1 receptors that mediate the calcium-inositol phospholipid signaling actions of AII; and nonpeptide (PD 123177) and peptide (CGP 42112A) antagonists that are selective for AT2 receptors of yet unknown function. In the adult rat brain, DuP 753 inhibited radioligand binding to the circumventricular organs and paraventricular nucleus but not to the lateral septum, subthalamic nucleus, and inferior olive. However, binding of 125I-labeled [Sar1,Ile8]AII in the latter regions was inhibited by the AT2 receptor antagonists PD 123177 and CGP 42112A. These areas showed similar displacement by the AT2 receptor subtype-specific antagonists in 2-week-old rats. In addition, radioligand binding at multiple sites of transient expression of AII receptors in 2-week-old rats, including several thalamic nuclei, the nuclei of the 3rd and 12th cranial nerves, geniculate bodies, cerebellum, and cingulate cortex, was displaced by the AT2 antagonists but not by DuP 753. These studies have demonstrated the presence of two AII receptor subtypes in the brain, one (AT1) in areas related to regulation of blood pressure, water intake, and pituitary hormone secretion, and one (AT2) whose function is not yet defined. The abundance and location of brain AT2 receptors in young animals, and the age-related changes in relative expression of the receptor subtypes, suggest that AII exerts specific actions according to the developmental stage of the central nervous system.
Radiation by aperture antennas of arbitrary shape fed by a covered microstrip line (2002)

Conformal antenna arrays are widely used in wireless communications. In order to design such arrays precisely a CAD tool which can handle complicated configurations is needed. A printed aperture antennas fed by a covered microstrip line in a triplate structure is an example of such arrays. The mixed potential integral equation (MPIE) CAD tool has been successfully used to investigate the behavior of the arbitrarily-shaped aperture antenna, fed by a covered microstrip line.