gebhart/patrepeval huggingface dataset:
Optimizing Fitting in Children Using Objective Measures Such as Neural Response Imaging and Electrically Evoked Stapedius Reflex Threshold (2007)

Otology & Neurotology publishes original articles relating to both clinical and basic science aspects of otology, neurotology, and cranial base surgery. As the foremost journal in its field, it has become the favored place for publishing the best of new science relating to the human ear and its diseases. The broadly international character of its contributing authors, editorial board, and readership provides the Journal its decidedly global perspective.
Type 3 Deiodinase Is Highly Expressed in Infiltrating Neutrophilic Granulocytes in Response to Acute Bacterial Infection (2008)

Infiltrating granulocytes during acute bacterial infection express D3. Our work supports the hypothesis that D3 plays an important role during chemical and bacterial inflammation. Whether the resulting decreased local bioavailability of thyroid hormones or rather the increased local availability of iodide is an important element of the innate immune response remains to be studied.
pH as a marker of breast cyst fluid biochemical type. (1987)

A previous study reported pH levels in human breast cyst fluid ranging from 7.00 to 7.80 with the cut off between Type I (high K+, low Cl-) and Type II (high Na+, high Cl-) cysts at pH 7.40. Our data indicate a wider range of pH levels in human breast cyst fluids with Type I cysts consistently having acidic levels below pH 7.0 while Type II cysts had pH levels greater than 7.0. Type I acidic cysts characteristically also contain greater amounts of organic acids than Type II cysts. Thus, the pH of breast cyst fluid appears to be related to the electrolyte profile.
Managing Business Process Flows (1999)

From the Publisher:
Managing Business Process Flows is a concise textbook for MBA level operations management courses. It provides a process-flows approach to studying some of the core concepts in operations with three steps: 1. Model and understand the process and its flows. 2. Study causal relationships between process structure and certain performance metrics. 3. Formulate implications for managerial actions by filtering out managerial levers (process drivers). MBPF shows how managers can control process structure and process drivers to achieve desired business process performance. This book is the result of the combined insight and experience of five operations management professors at the Kellogg Graduate School of Management, Northwestern University. An educational version of Process Model is included with this textbook.
Performance Evaluation and Comparative Analysis of SubCarrier Modulation Wake-up Radio Systems for Energy-Efficient Wireless Sensor Networks (2013)

Energy-efficient communication is one of the main concerns of wireless sensor networks nowadays. A commonly employed approach for achieving energy efficiency has been the use of duty-cycled operation of the radio, where the node's transceiver is turned off and on regularly, listening to the radio channel for possible incoming communication during its on-state. Nonetheless, such a paradigm performs poorly for scenarios of low or bursty traffic because of unnecessary activations of the radio transceiver. As an alternative technology, Wake-up Radio (WuR) systems present a promising energy-efficient network operation, where target devices are only activated in an on-demand fashion by means of a special radio signal and a WuR receiver. In this paper, we analyze a novel wake-up radio approach that integrates both data communication and wake-up functionalities into one platform, providing a reconfigurable radio operation. Through physical experiments, we characterize the delay, current consumption and overall operational range performance of this approach under different transmit power levels. We also present an actual single-hop WuR application scenario, as well as demonstrate the first true multi-hop capabilities of a WuR platform and simulate its performance in a multi-hop scenario. Finally, by thorough qualitative comparisons to the most relevant WuR proposals in the literature, we state that the proposed WuR system stands out as a strong candidate for any application requiring energy-efficient wireless sensor node communications.
Interimplant papilla preservation in the esthetic zone: a report of six consecutive cases. (2003)

Simultaneous removal of multiple adjacent teeth in the anterior maxilla often leads to collapse of the labial bony plate as well as flattening of the interproximal bony scallop, resulting in long implant restorations with missing interimplant papillae. An interimplant papilla preservation technique involving alternate immediate implant placement and provisionalization, one following the osseointegration healing period of the other, was introduced. All 14 implants placed in six consecutive patients maintained osseointegration after a mean functioning time of 22.6 months (range 12 to 34 months). A highly satisfactory esthetic outcome and a papilla index score of 3 was observed in all patients.
Retroviral expression of recombinant p47phox protein by Epstein-Barr virus-transformed B lymphocytes from a patient with autosomal chronic granulomatous disease (1992)

Patients with chronic granulomatous disease (CGD) have recurrent infections resulting from a failure of phagocytic cells to produce superoxide. One third of CGD patients have an autosomal gene defect resulting in absence of p47phox protein, a cytoplasmic component critical to superoxide production by phagocytic cells. cDNA encoding p47phox has been cloned and recombinant p47phox (rp47phox) restores superoxide-generating activity to a cell-free assay containing cell membranes and cytosol from p47phox-deficient CGD neutrophils. The goal of the present study was to determine the feasibility of retrovirus mediated expression of rp47phox in the HL60 and U937 human hematopoietic cell lines, and in an Epstein-Barr virus transformed B-lymphocyte cell line (EBV-BCL) derived from a p47phox-deficient CGD patient. Normal EBV-BCL contain p47phox and generate small amounts of superoxide, while this CGD EBV-BCL lacks any detectable p47phox protein. Defective amphotropic retrovirus containing p47phox sequence inserted in the LXSN vector in sense and antisense orientations were used to transduce HL60, U937, and CGD EBV-BCL. p47phox mRNA sequence was detected in cells transduced with either sense or antisense retroviral constructs while rp47phox protein was detected only with the sense construct. The amount of rp47phox protein produced within these cells was greater than the native p47phox present in uninduced HL60 or U937 cells, but substantially less than that present in normal neutrophils, induced HL60 cells, or even normal EBV-BCL. Differentiation of transduced HL60 cells and the associated production of native p47phox in response to dimethyl sulfoxide was not affected. These studies demonstrate that retrovirus constructs can be used to mediate stable expression of rp47phox protein in human hematopoietic cell lines and can restore rp47phox protein within the cytosol of p47phox-deficient EBV-BCL from patients with CGD.
Estrogenic Activities of Nitrophenols in Diesel Exhaust Particles1 (2004)

We recently isolated 3-methyl-4-nitrophenol (4-nitro-m-cresol; PNMC) and 4-nitro-3-phenylphenol (PNMPP) from diesel exhaust particles (DEP) and identified them as vasodilators. Because these compounds are alkylphenolic derivatives that might mimic hormones, we evaluated their estrogenic activity by using recombinant yeast screens, myometrial contractility assays, and in vivo uterotrophic assays. Recombinant yeast screen assays showed that both PNMC and PNMPP possess estrogenic activity. Furthermore, ovariectomized 25-day-old immature female rats injected with PNMC and PNMPP subcutaneously for 2 days showed significant increases in uterine weight among those receiving 100 mg/kg PNMC and 0.1 and 1.0 mg/kg PNMPP. To clarify further the estrogenic activity of PNMC and PNMPP, rat uterine horns were monitored in organ bath chambers for myometrial contractility in response to oxytocin (OT). Significant differences occurred in the initial and maximum contractilities to OT at 0.25 and 25 mIU/ml in uterine horns obtained from animals treated with 100 mg/kg PNMC and in the maximum contractilities to OT at 0.025, 0.25, and 25 mIU/ml in those from rats treated with 0.1 mg/kg PNMPP. These results clearly demonstrated that PNMC and PNMPP in DEP have estrogenic activity both in vitro and in vivo and might therefore be considered as endocrine-disrupting chemicals.
Chemistry of fullerenes C60 and C70 formation in flames (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry of fullerenes C60 and C70 formation in flamesChristopher J. Pope, Joseph A. Marr, and Jack B. HowardCite this: J. Phys. Chem. 1993, 97, 42, 11001–11013Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/j100144a018https://doi.org/10.1021/j100144a018research-articleACS PublicationsRequest reuse permissionsArticle Views609Altmetric-Citations152LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
An analog implementation of discrete-time cellular neural networks (1992)

An analog circuit structure for the realization of discrete-time cellular neural networks (DTCNNs) is introduced. The computation is done by a balanced clocked circuit based on the idea of conductance multipliers and operational transconductance amplifiers. The circuit is proposed for a one-neighborhood on a hexagonal grid, but can also be modified to larger neighborhoods and/or other grid topologies. A layout was designed for a standard CMOS process, and the corresponding HSPICE simulation results are given. A test chip containing 16 cells was fabricated, and measurements of the transfer characteristics are provided. The functional behavior is demonstrated for a simple example.
Treatment of proximal deep vein thrombosis with a novel synthetic compound (SR90107A/ORG31540) with pure anti-factor Xa activity - A phase II evaluation (2000)

Background-Patients with venous thromboembolism require initial treatment with an immediate-acting anticoagulant, low-molecular-weight heparin. We evaluated a novel synthetic factor Xa inhibitor (SR90107a/ORG31540) as an alternative treatment. Methods and Results-A randomized-parallel-group, phase II trial to assess the efficacy and safety of SR90107a/ORG31540 (5, 7.5, or 10 mg once daily) relative to low-molecular-weight heparin (dalteparin, 100 IU/kg twice daily) in symptomatic proximal deep vein thrombosis. The primary outcome measure was the change in thrombus mass, assessed by ultrasonography of the leg veins and perfusion lung scintigraphy, performed at baseline and day 7+/-1. A positive outcome was defined as improvement of the ultrasound and/or perfusion scan result without deterioration of either test. Other outcome measures included symptomatic, recurrent venous thromboembolism and major bleeding for a period of 3 months. All outcomes were interpreted with the observer unaware of treatment allocation. A positive primary outcome was observed in 46 of 100 (46%), 52 of 108 (48%), 48 of 115 (42%), and 56 of 115 (49%), respectively, of the subjects given 5, 7.5, or 10 mg SR90107a/ORG31540 or dalteparin. There were 8 recurrent thromboembolic complications (2.4%) in the 334 patients treated with SR90107a/ORG31540 and 6 (5.0%) in the 119 dalteparin patients, a difference of 2.6% in favor of SR90107a/ORG31540 (95% CI -2.1% to 10.1%). The incidence of bleeding was low and was similar among the groups. Conclusions-The factor Xa inhibitor SR90107a/ORG31540 appears to be an effective and safe treatment for patients with deep vein thrombosis across a wide range of doses. This synthetic compound merits evaluation in phase III studies.
Increase in Gamma Interferon-Secreting CD8<sup>+</sup>, as Well as CD4<sup>+</sup>, T Cells in Lungs following Aerosol Infection with<i>Mycobacterium tuberculosis</i> (1999)

Although it is well established that CD4(+) T cells are required for the protective immune response against tuberculosis (TB), there is some evidence that CD8(+) T cells are also involved in the host response to Mycobacterium tuberculosis. There is, however, a paucity of information on the pulmonary CD8(+) T-cell response during infection. We therefore have compared the changes in both CD8(+) and CD4(+) T cells following aerosol infection with M. tuberculosis. There was an observed delay between the peak of infection and the activated T-cell response in the lung. The kinetics of CD8(+) and CD4(+) T-cell responses in the lung were identical, both peaking at week 8, 4 weeks later than the peak of cellular response in draining lymph nodes. Similar changes in activation/memory phenotypes occurred on the pulmonary CD8(+) and CD4(+) T cells. Following in vitro restimulation, both subsets synthesized gamma interferon, a cytokine essential for controlling M. tuberculosis infection. Since lung CD8(+) T cells are actively expanded during aerosol M. tuberculosis infection, it is important that both CD8(+) and CD4(+) T cells be targeted in the design of future TB vaccines.
Construction of efficient OR-based deletion - tolerant coding schemes (2006)

Fault-tolerant data layouts for storage systems are based on the principle to add redundancy to groups of data blocks and store them in different fault regions. Commonly, XOR-based codes are used with an optimal redundancy overhead but with the disadvantage of relatively high calculation costs. We present a scheme that encodes input data in a highly redundant code and exploits that redundancy for a fault tolerance scheme. It allows to recalculate missed bits in fewer steps than needed for XOR-based schemes. This simple and efficient en- and decoding requires an appropriate hardware architecture or a highly parallel microprocessor architecture. Particularly, disjunctions over many input bits must be calculated, e.g. by wide OR-gates or busses that are driven by multiple logic input lines. The high redundant encoding is combined with data compression for separated data streams, each stream dedicated to a storage device. The compression not only eliminates the introduced redundancy of the used code, it also eliminates redundancy in the input data.
Novel design of rubber tube actuator improving mountability and drivability for assisting colonosocope insertion (2011)

Recently, colonoscopy has become much more important with increasing number of colonic diseases. However, the inspection time depends on the doctor's skill strongly. In this research, we aim at development of a tube type rubber pneumatic actuator for assisting insertion of a large intestine endoscope. This actuator can be wound around endoscopes in a spiral configuration. In previous paper, two types of actuator were developed and some experiments were conducted. However, there were drawbacks, one actuator could not generate enough output, and the other one was difficult to mount on endoscopes. In this paper, novel actuator has been designed by non-linear FEM (Finite Element Method) to realize high mountability and drivability. The actuator is configured with three air chambers, and by applying pneumatic pressure to each chamber in proper sequence, elliptical motion of the actuator has been confirmed by non-linear FEM analysis and experiments using motion capture system. Moreover the self propelling velocity and the traction force have been increased compared to previous actuators and effectiveness of this actuator has been confirmed from the phantom experiments.
Prevalence of different comorbidities in COPD patients by gender and GOLD stage (2015)

All comorbidities increased their prevalence progressively up to the last stage of COPD severity, except the cardio-vascular and the metabolic ones which dropped in the IV GOLD stage, presumably due to the high mortality rate in this severe COPD stage. The gender-dependency of comorbidities was confirmed in general terms, even if lung cancer proved a dramatic increase almost independently of sex.
Development and Initial Assessment of a Patient Education Video about Pharmacogenetics (2017)

As few patient-friendly resources about pharmacogenetics are currently available, we aimed to create and assess a patient educational video on pharmacogenetic testing. A primary literature and resources review was conducted to inform the content and the format of the video. The educational video was then created using a commercially available animation program and pilot tested in focus groups of the general public and by an online survey of pharmacists. Emerging themes from the focus groups and survey indicate a desire for appropriate risk contextualization and specific examples when pharmacogenetic testing may be beneficial. Focus group participants also expressed a preference for a video with live action, and more text to reinforce concepts. Pharmacists generally felt that the video was understandable for patients and relevant for decision-making regarding testing. Using this initial feedback and the identification of important concepts to include in pharmacogenetics educational tools, we plan to revise the video, perform additional evaluations, and publish the video for public use in the future.
A decision-theoretic approach to the test allocation problem in partition testing (2002)

A partition testing strategy consists of two components: a partitioning scheme which determines the way in which the program's input domain is partitioned into subdomains; and an allocation of test cases which determines the exact number of test cases selected from each subdomain. This paper investigates the problem of determining the test allocation when a particular partitioning scheme has been chosen. We show that this problem can be formulated as a classic problem of decision-making under uncertainty, and analyze several well known criteria to resolve this kind of problem. We present algorithms that solve the test allocation problem based on these criteria, and evaluate these criteria by means of a simulation experiment. We also discuss the applicability and implications of applying these criteria in the context of partition testing.
PFG-NMR Measurements of the Self-Diffusion Coefficients of Water in Equilibrium Poly(HEMA-<i>co</i>-THFMA) Hydrogels (2002)

The self-diffusion coefficients for water in a series of copolymers of 2-hydroxyethyl methacrylate, HEMA, and tetrahydrofurfuryl methacrylate, THFMA, swollen with water to their equilibrium states have been studied at 310 K using PFG-NMR. The self-diffusion coefficients calculated from the Stejskal-Tanner equation, D(obs), for all of the hydrated polymers were found to be dependent on the NMR storage time, as a result of spin exchange between the proton reservoirs of the water and the polymers, reaching an equilibrium plateau value at long storage times. The true values of the diffusion coefficients were calculated from the values of D(obs) in the plateau regions by applying a correction for the fraction of water protons present, obtained from the equilibrium water contents of the gels. The true self-diffusion coefficient for water in polyHEMA obtained at 310 K by this method was 5.5 x 10(-10) m(2)s-1. For the copolymers containing 20% HEMA or more a single value of the self-diffusion coefficient was found, which was somewhat larger than the corresponding values obtained for the macroscopic diffusion coefficient from sorption measurements. For polyTHFMA and copolymers containing less than 20% HEMA, the PFG-NMR stimulated echo attenuation decay curves and the log-attenuation plots were characteristic of the presence of two diffusing water species. The self-diffusion coefficients of water in the equilibrium-hydrated copolymers were found to be dependent on the copolymer composition, decreasing with increasing THFMA content.
High carbon doping efficiency of bromomethanes in gas source molecular beam epitaxial growth of GaAs (1991)

Carbon tetrabromide (CBr4) and bromoform (CHBr3) have been studied as carbon doping sources for GaAs grown by gas source molecular beam epitaxy (GSMBE) with elemental Ga and thermally cracked AsH3. Hole concentrations in excess of 1×1020 cm−3 have been measured by Hall effect in both CBr4- and CHBr3-doped GaAs, which agrees closely with the atomic C concentration from secondary-ion mass spectrometry, indicating complete electrical activity of the incorporated carbon. The GaAs growth rate is unaffected by the CBr4 and CHBr3 fluxes over the range of dopant flow investigated. The efficiencies of carbon incorporation from CBr4 and CHBr3 are, respectively, 750 and 25 times that of trimethylgallium (TMG), which is commonly employed as a carbon doping source in metalorganic MBE (MOMBE). The sensitivity of carbon incorporation to varying substrate temperature and V/III ratio has been observed to be significantly reduced with CBr4 and CHBr3 from that obtained under similar growth conditions with TMG in MOMBE.
Chapter 20: Coral Reefs (1957)

The beauty of color and form and the overwhelming variety of life on coral reefs are both legendary and real. Nowhere else in the seas is there such a bewildering range of living things, and perhaps nowhere else is the physical and biological pattern so uniform, characteristic, and widespread as in the coral reef. Reefs are scattered over an area of 190,000,000 square kilometers (68,000,000 square miles) wherever a suitable substratum lies within the lighted waters of the tropics beyond the influence of continental sediments, and away from...