gebhart/patrepeval huggingface dataset:
From Physiological Signals to Emotions: Implementing and Comparing Selected Methods for Feature Extraction and Classification (2005)

Little attention has been paid so far to physiological signals for emotion recognition compared to audio-visual emotion channels, such as facial expressions or speech. In this paper, we discuss the most important stages of a fully implemented emotion recognition system including data analysis and classification. For collecting physiological signals in different affective states, we used a music induction method which elicits natural emotional reactions from the subject. Four-channel biosensors are used to obtain electromyogram, electrocardiogram, skin conductivity and respiration changes. After calculating a sufficient amount of features from the raw signals, several feature selection/reduction methods are tested to extract a new feature set consisting of the most significant features for improving classification performance. Three well-known classifiers, linear discriminant function, k-nearest neighbour and multilayer perceptron, are then used to perform supervised classification
Clinical practice guidelines for hepatocellular carcinoma: The Japan Society of Hepatology 2017 (4th JSH‐HCC guidelines) 2019 update (2019)

The fourth version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence-based medicine and partly to the Grading of Recommendations Assessment, Development, and Evaluation system, which was published in October 2017 in Japanese. New or revised recommendations were described, herein, with a special reference to the surveillance, diagnostic, and treatment algorithms.
Allocation of Discrete Energy on a Cloud-Computing Datacenter Using a Digital Power Grid (2012)

Electrical power supply of data centers constitutes major operational costs. In this paper, we focus on providing the supplying energy to exact match the consumption demands by using the properties of a digital power grid. Different from the present power grid, where energy is supplied continuously and in amounts to satisfy large demands, the digital power grid supplies energy in the form of packets and upon request. Energy packets are specifically addressed to one, or multiple servers and to no others, and they carry the amount of energy that has been requested. To evaluate the level of energy supply, we model the consumption time of a server as an ON-OFF Markov chain. Through simulation, we show that the digital grid not only reduces the energy safety margins used by current energy providers to assure system stability but it also highly satisfies the energy requests of data center servers when the capacity of the power grid equals the average energy request and without a safety margin.
Superconducting Wires of High T<sub>c</sub> Oxides (1987)

Superconducting wires of Y–Ba–Cu–O system have been investigated. Wires were fabricated by powder method. The wires were successfully reduced to a small diameter. Wires of Y 1 Ba 2 Cu 3 O 7 exhibit zero resistance at 90 K.
Total and Attributable Costs of Surgical-Wound Infections at a Canadian Tertiary-Care Center (1998)

Wound infections contribute markedly to extra days of hospitalization and related costs. The AEP method is applied easily to determine attributable days of care and costs of wound infections, which are necessary to calculate the cost-benefit of infection control programs.
Preclinical evaluation of CPT-11 and its active metabolite SN-38. (1996)

CPT-11 (irinotecan) is a water-soluble analogue of camptothecin (CPT), an antitumor drug extracted from the Chinese tree Camptotheca acuminata. SN-38 is an active metabolite of CPT-11 that contributes significantly to its activity. The antitumor effects of CPT-11 and SN-38 are exerted through a novel mechanism of action; inhibition of DNA topoisomerase I. CPT-11 and its metabolite have demonstrated potent inhibitory activity against a variety of cancer cell lines in vitro and against several murine and human tumors grafted in mice in vivo, including those that express multidrug resistance. CPT-11 has also shown synergistic activity in combination with 5-fluorouracil and cisplatin in vitro. No irreversible or unusual toxicities were observed with CPT-11 in animal toxicity studies. In summary, the preclinical profile of CPT-11 confirmed this drug to be an attractive candidate for clinical development.
Enabling communication concurrency through flexible MPI endpoints (2014)

MPI defines a one-to-one relationship between MPI processes and ranks. This model captures many use cases effectively; however, it also limits communication concurrency and interoperability between MPI and programming models that utilize threads. This paper describes the MPI endpoints extension, which relaxes the longstanding one-to-one relationship between MPI processes and ranks. Using endpoints, an MPI implementation can map separate communication contexts to threads, allowing them to drive communication independently. Endpoints also enable threads to be addressable in MPI operations, enhancing interoperability between MPI and other programming models. These characteristics are illustrated through several examples and an empirical study that contrasts current multithreaded communication performance with the need for high degrees of communication concurrency to achieve peak communication performance.
Fully Automated Enhanced Tumor Compartmentalization: Man vs. Machine Reloaded (2016)

BT and SB provide comparable segmentation results in a clinical setting. SB provided similar SPD measures to BT and GT, but differed in the volume analysis in one of the four clinical raters. A major strength of BT may its independence from human interactions, it can thus be employed to handle large datasets and to associate tumor volumes with clinical and/or molecular datasets ("-omics") as well as for clinical analyses of brain tumor compartment volumes as baseline outcome parameters. Due to its multi-compartment segmentation it may provide information about GBM subcompartment compositions that may be subjected to clinical studies to investigate the delineation of the target volumes for adjuvant therapies in the future.
Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway (2010)

Genome-wide active DNA demethylation in primordial germ cells (PGCs), which reprograms the epigenome for totipotency, is linked to changes in nuclear architecture, loss of histone modifications, and widespread histone replacement. Here, we show that DNA demethylation in the mouse PGCs is mechanistically linked to the appearance of single-stranded DNA (ssDNA) breaks and the activation of the base excision repair (BER) pathway, as is the case in the zygote where the paternal pronucleus undergoes active DNA demethylation shortly after fertilization. Whereas BER might be triggered by deamination of a methylcytosine (5mC), cumulative evidence indicates other mechanisms in germ cells. We demonstrate that DNA repair through BER represents a core component of genome-wide DNA demethylation in vivo and provides a mechanistic link to the extensive chromatin remodeling in developing PGCs.
A new plastic surgical technique for adult congenital webbed penis (2012)

Adult webbed penis with complaints of discomfort or psychological pressure due to a poor profile should be indicators for surgery. Good corrective surgery should expose the glans and coronal sulcus, match the penile skin length to the penile shaft length dorsally and ventrally, and provide a normal penoscrotal junction. Our new technique is a safe and effective method for the correction of adult webbed penis, which produces satisfactory results.
Horizontal and vertical structuring of typed graph transformation systems (1996)

Using a categorical semantics that has been developed recently as a basis, we study composition and refinement as horizontal and vertical structuring techniques for typed graph transformation systems. Composition of graph transformation systems with respect to common subsystems is shown to be compatible with the semantics, i.e. , the semantics of the composed system is obtained as the composition of the semantics of the component systems. Moreover, the structure of a composed graph transformation system is preserved during a refinement step in the sense that compatible refinements of the components induce a refinement of the composition. The concepts and results are illustrated by a sample development of a small information system using entity relationship modelling techniques.
SYNTAX AND LEXICAL STATISTICS IN ANAPHORA RESOLUTION (1995)

We describe a syntactically based salience algorithm for pronominal anaphora resolution and a procedure for reevaluating the decisions of the algorithm on the basis of statistically modeled lexical semantic/pragmatic preferences. We report the results of an extensive blind test of both systems on computer manual text. We discuss the implications of these results for the comparative roles of syntactically defined salience and statistically measured lexical preference in determining the references of pronouns in text.
Reactions of carbon dioxide and hydrogen sulfide with some alkanolamines (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of carbon dioxide and hydrogen sulfide with some alkanolaminesRobert N. Maddox, Gilbert J. Mains, and Mahmud A. RahmanCite this: Ind. Eng. Chem. Res. 1987, 26, 1, 27–31Publication Date (Print):January 1, 1987Publication History Published online1 May 2002Published inissue 1 January 1987https://pubs.acs.org/doi/10.1021/ie00061a006https://doi.org/10.1021/ie00061a006research-articleACS PublicationsRequest reuse permissionsArticle Views1164Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Dose reduction in digital breast tomosynthesis using a penalized maximum likelihood reconstruction (2009)

Digital breast tomosynthesis (DBT) is a 3D imaging modality with limited angle projection data. The ability of tomosynthesis systems to accurately detect smaller microcalcifications is debatable. This is because of the higher noise in the projection data (lower average dose per projection), which is then propagated through the reconstructed image . Reconstruction methods that minimize the propagation of quantum noise have potential to improve microcalcification detectability using DBT. In this paper we show that penalized maximum likelihood (PML) reconstruction in DBT yields images with an improved resolution/noise tradeoff as compared to conventional filtered backprojection (FBP). Signal to noise ratio (SNR) using PML was observed to be higher than that obtained using the standard FBP algorithm. Our results indicate that for microcalcifications, using the PML algorithm, reconstructions obtained with a mean glandular dose (MGD) of 1.5 mGy yielded better SNR than that those obtained with FBP using a 4mGy total dose. Thus perhaps total dose could be reduced to one-third or lower with same microcalcification detectability, if PML reconstruction is used instead of FBP. Visibility of low contrast masses with various contrast levels were studied using a contrast-detail phantom in a breast shape structure with an average breast density. Images generated using various dose levels indicate that visibility of low contrast masses generated using PML reconstructions are significantly better than those generated using FBP. SNR measurements in the low-contrast study did not appear to correlate with the visual subjective analysis of the reconstruction indicating that SNR is not a good figure of merit to be used.
Improved performance and reliability of N<sub>2</sub>O-grown oxynitride on 6H-SiC (2000)

This letter reports, for the first time, N/sub 2/O-grown oxides on both n-type and p-type 6H-SiC wafers. It is demonstrated that the N/sub 2/O-grown technique leads to not only greatly improved SiC/SiO/sub 2/ interface and oxide qualities, but also considerably enhanced device reliabilities as compared to N/sub 2/O-nitrided and conventional thermally oxidized devices. These improvements are especially obvious for p-type SiC MOS devices, indicating that N/sub 2/O oxidation could be a promising technique for fabricating enhancement-type n-channel SiC MOSFETs.
Cloning of <i>Phanerochaete chrysosporium leu2</i> by Complementation of Bacterial Auxotrophs and Transformation of Fungal Auxotrophs (1998)

A Phanerochaete chrysosporium cDNA library was constructed in an expression vector that allows expression in both Escherichia coli and Saccharomyces cerevisiae. This expression vector, lambda YES, contains the lacZ promoter for expression in E. coli and the GAL1 promoter for expression in yeast. A number of genes were cloned by complementation of bacterial amino acid auxotrophs. The cDNA encoding the beta-isopropylmalate dehydrogenase from P. chrysosporium was characterized further. The genomic clone (gleu2) was subsequently isolated and was used successfully as a selectable marker to transform P. chrysosporium auxotrophs for LEU2. Protoplasts for transformation were prepared with readily obtained conidiospores rather than with basidiospores, which were used in previous P. chrysosporium transformation procedures. The method described here allows other genes to be isolated from P. chrysosporium for use as selectable markers.
Cellular Factors Promoting Resistance to Effective Treatment of Glioma with Oncolytic Myxoma Virus (2014)

Oncolytic virus therapy is being evaluated in clinical trials for human glioma. While it is widely assumed that the immune response of the patient to the virus infection limits the utility of the therapy, investigations into the specific cell type(s) involved in this response have been performed using nonspecific pharmacologic inhibitors or allogeneic models with compromised immunity. To identify the immune cells that participate in clearing an oncolytic infection in glioma, we used flow cytometry and immunohistochemistry to immunophenotype an orthotopic glioma model in immunocompetent mice after Myxoma virus (MYXV) administration. These studies revealed a large resident microglia and macrophage population in untreated tumors, and robust monocyte, T-, and NK cell infiltration 3 days after MYXV infection. To determine the role on the clinical utility of MYXV therapy for glioma, we used a combination of knockout mouse strains and specific immunocyte ablation techniques. Collectively, our experiments identify an important role for tumor-resident myeloid cells and overlapping roles for recruited NK and T cells in the clearance and efficacy of oncolytic MYXV from gliomas. Using a cyclophosphamide regimen to achieve lymphoablation prior and during MYXV treatment, we prevented treatment-induced peripheral immunocyte recruitment and, surprisingly, largely ablated the tumor-resident macrophage population. Virotherapy of cyclophosphamide-treated animals resulted in sustained viral infection within the glioma as well as a substantial survival advantage. This study demonstrates that resistance to MYXV virotherapy in syngeneic glioma models involves a multifaceted cellular immune response that can be overcome with cyclophosphamide-mediated lymphoablation.
Localized Functionalization of Individual Colloidal Carriers for Cell Targeting and Imaging (2007)

Fabricating drug particles for therapeutic delivery and imaging presents important challenges in the design of the particle surfaces. Drug nanoparticle surfaces are currently functionalized with site-specific targeting ligands, biocompatible polymers, or fluorophore-polymer conjugates for specific imaging. However, if these functionalizations were to be synthesized on the drug carrier in localized, nanoscale regions on the particle surface, new schemes of drug delivery could be realized. Here we describe the use of our particle lithography technique that enables the synthesis of individual colloidal carrier assemblies that can be imaged and targeted to integrin-expressing cells. We show localized adhesion specificity for cells expressing the target integrin followed by receptor-mediated endocytosis. With the addition of localized delivery by adding drug nanoparticles to a specific region on the particle surface, our colloidal carrier assemblies have the potential to target, deliver therapeutic agents to, sense, and image diseased endothelium.
Blood-Brain Barrier Disruption in the Treatment of Brain Tumors (2010)

Standard chemotherapy administered systemically has a limited efficacy in the treatment of brain tumors. One of the major obstacles in the treatment of brain neoplasias is the impediment to delivery across the intact blood-brain barrier (BBB). Many innovative approaches have been developed to circumvent this obstacle. One such strategy is BBB disruption (BBBD), which successfully increases the delivery of antineoplastic agents to the central nervous system (CNS). This chapter describes the application of the BBBD technique in rats. Different methods to evaluate and measure BBB permeability following hyperosmolar mannitol infusion including Evans blue staining, albumin immunohistochemistry, and dynamic magnetic resonance imaging are also described.
Biocatalytic Deracemization Techniques: Dynamic Resolutions and Stereoinversions (1997)

Biocatalytic deracemization techniques, i.e. reactions allowing the transformation of a racemic mixture into one single enantiomeric product in quantitative yield, are reviewed. This goal may be achieved via two different principles: (i) Dynamic resolution: If a (biocatalytic) kinetic resolution of a substrate is performed under conditions where the (chirally labile) substrate enantiomers are equilibrating (racemizing), all of the substrate is transformed into a single product enantiomer in 100% theoretical yield. Substrate racemization may be achieved either by chemical or biocatalysis. The major advantages of these so-called 'Dynamic Resolutions' are two-fold. They exhibit higher enantio-selectivities as compared to classic resolutions and due to the absence of an unwanted remaining (substrate) enantiomer the separation of the substrate-product mixture can be omitted. This concept has been applied to a variety of compounds such as α-amino acids, hemithioacetal esters, α-(hetero)arylcarboxylic acids, α-substituted nitriles, cyanohydrin esters, α-substituted thioesters, as well as 4-substituted oxazolin-5-ones and thiazolin-5-ones. (ii) Stereoinversion: If one enantiomer from a racemic substrate is transformed into its mirror image by leaving the other enantiomer untouched, the reaction comprises a formal stereoinversion leading to a single product enantiomer in 100% theoretical yield. This concept has been verified with the transformation of racemic secondary alcohols via biocatalytic inversion of one enantiomer by means of a two-step oxidation-reduction sequence catalyzed by whole microbial cells.
Differential Thermal Studies with Simultaneous Gas Evolution Profiles (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDifferential Thermal Studies with Simultaneous Gas Evolution ProfilesW. M. Ayres and E. M. BensCite this: Anal. Chem. 1961, 33, 4, 568–572Publication Date (Print):April 1, 1961Publication History Published online1 May 2002Published inissue 1 April 1961https://pubs.acs.org/doi/10.1021/ac60172a025https://doi.org/10.1021/ac60172a025research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Iterative linearization methods suited for digital pre-distortion of power amplifiers (2005)

This paper deals with iterative linearization of a nonlinear dynamical system. The methods proposed are suited for digital pre-distortion of power amplifiers working close to saturation, as it is common for efficiency reasons. Two methods (a well known successive approximation method based on a fixed-point formulation and a Newton method) are compared with respect to convergence speed, robustness against model uncertainties, and complexity. The presented methods are used to linearize a Volterra model of a measured power amplifier.
Faster Teaching via POMDP Planning (2015)

Human and automated tutors attempt to choose pedagogical activities that will maximize student learning, informed by their estimates of the student's current knowledge. There has been substantial research on tracking and modeling student learning, but significantly less attention on how to plan teaching actions and how the assumed student model impacts the resulting plans. We frame the problem of optimally selecting teaching actions using a decision-theoretic approach and show how to formulate teaching as a partially observable Markov decision process planning problem. This framework makes it possible to explore how different assumptions about student learning and behavior should affect the selection of teaching actions. We consider how to apply this framework to concept learning problems, and we present approximate methods for finding optimal teaching actions, given the large state and action spaces that arise in teaching. Through simulations and behavioral experiments, we explore the consequences of choosing teacher actions under different assumed student models. In two concept-learning tasks, we show that this technique can accelerate learning relative to baseline performance.
The Network of Innovators in Jena: An Application of Social Network Analysis (2004)

First draft- Please do not cite without permission of the authors We apply social network analysis methods to describe the evolution of the innovator network of Jena, Germany in the period from 1995 to 2001. We find this evolution to be directed towards an increasing focus on core competencies of the local innovation system. Further we analyze the network resulting from R&amp;D cooperations and explain- by means of network regression techniques- that the job mobility of scientists and the technological overlap between the actors, rather than past cooperations, can best predict the resulting structure. We also observe an increasing importance of the university while the former “Kombinate ” begin to lose their prominent role.