gebhart/patrepeval huggingface dataset:
Clinical Relevance of Tolerance to Nitrovasodilators (1991)

Summary: The question of whether or not the therapeutic efficacy of the nitrates is attenuated with chronic use has been studied mainly since the widespread use of controlled-release preparations for oral or transdermal administration, which lead to sustained high plasma nitrate concentrations. There are many possible reasons for the conflicting results published in regard to the clinical relevance of nitrate tolerance. Poor quality trials or inappropriate design should certainly be taken into account. Whether results obtained in laboratory circumstances, e.g., with maximal exercise testing in angina pectoris, are misleading with regard to the occurrence of attenuation in daily life circumstances is not likely but cannot be excluded. There is no evidence that attenuation is specific for one disease state or another, but interpatient differences in regard to the development of nitrate attenuation seem to exist. Nitrate tolerance is probably seen with all nitrate products. High and frequent dosing, but mainly use of controlled-release preparations for oral or transdermal administration, will favor the development of attenuation. In the many studies where nitrate-free periods are introduced, such regimens are found to be superior to regimens without a nitrate-free period. To obtain an antianginal effect during the nitrate-free period, and to avoid nitrate withdrawal phenomena, β-blockers or calcium antagonists should be used. Interest in using N-acetylcysteine to counteract nitrate tolerance is at this moment not proven.
Critical Power for Asymptotic Connectivity in Wireless Networks (1999)

In wireless data networks each transmitter’s power needs to be high enough to reach the intended receivers, while generating minimum interference on other receivers sharing the same channel. In particular, if the nodes in the network are assumed to cooperate in routing each others’ packets, as is the case in ad hoc wireless networks, each node should transmit with just enough power to guarantee connectivity in the network. Towards this end, we derive the critical power a node in the network needs to transmit in order to ensure that the network is connected with probability one as the number of nodes in the network goes to infinity. It is shown that if n nodes are placed in a disc of unit area in ℜ2 and each node transmits at a power level so as to cover an area of πr 2 = (log n + c(n))/n, then the resulting network is asymptotically connected with probability one if and only if c(n) → +∞.
The Galactic Centre - A spectroscopic and imaging study with the LWS (1999)

We report observations of a fully sampled (spatially and spectrally) mapping of the central few arcminutes around the Galactic Centre, using the ISO LWS. The maps show the relative spatial distributions in about 20 different emission and absorption lines. The circumnuclear disc is clearly traced by some molecular lines, whilst the central region dominates in other atomic and ionised lines. Spectra are also be shown of several other interesting sources within the Galactic Centre cloud ensemble, including Sgr A West and the `Sickle' cluster.
Object recognition as ranking holistic figure-ground hypotheses (2010)

We present an approach to visual object-class recognition and segmentation based on a pipeline that combines multiple, holistic figure-ground hypotheses generated in a bottom-up, object independent process. Decisions are performed based on continuous estimates of the spatial overlap between image segment hypotheses and each putative class. We differ from existing approaches not only in our seemingly unreasonable assumption that good object-level segments can be obtained in a feed-forward fashion, but also in framing recognition as a regression problem. Instead of focusing on a one-vs-all winning margin that can scramble ordering inside the non-maximum (non-winning) set, learning produces a globally consistent ranking with close ties to segment quality, hence to the extent entire object or part hypotheses spatially overlap with the ground truth. We demonstrate results beyond the current state of the art for image classification, object detection and semantic segmentation, in a number of challenging datasets including Caltech-101, ETHZ-Shape and PASCAL VOC 2009.
Antimicrobial activity of cotton fabric pretreated by microwave plasma and dyed with onion skin and onion pulp extractions (2007)

Onion has been extracted to obtain colour compound for dyeing cotton fabric and the antimicrobial property of dyed fabric studied. The fabric is first desiccated with ethanol and then pretreated with low-temperature microwave plasma for 4 s with oxygen pressure of 0.2 Torr and power of 800 W. Thereafter, the plasma-treated samples are grafted for 10, 30, 60 min at 70 C with onion skin and onion pulp extractions. The best inhibition zone of anti Staphylococcus aureus is found to be 1.1-0.8 cm by 10 min grafting time of onion skin extraction and 0.7-0.5 cm by 30 min grafting time of onion pulp extraction. The samples with 10 and 30 min grafting of both onion skin and onion pulp show anti S. aureus ability even after 5 times test washing, but both the samples lost their anti S. aureus property with 60 min grafting. The FTIR-ATR spectrum of dyed cotton fabric shows flavonoids’ functional peak at 1624 cm of onion skin that provides cotton fabric brown colour with wash fastness rating of 4.
Fluoxetine differentially alters alcohol intake and other consummatory behaviors in problem drinkers (1990)

The effects of fluoxetine, a relatively selective long-acting serotonin uptake inhibitor, on the consumption of alcoholic and nonalcoholic drinks, cigarette smoking, and body weight were assessed in 29 men who were early stage problem drinkers. After a 2-week baseline, subjects were randomly assigned to receive 40 mg/day fluoxetine (n = 8), 60 mg/day fluoxetine (n = 11), or placebo (n = 10) for 4 weeks. Fluoxetine 60 mg/day decreased mean daily alcoholic drinks from (X +/- SEM) 8.3 +/- 0.7 during baseline to 6.9 +/- 0.7 and decreased total drinks per 14 days from 115.8 +/- 9.3 to 96.5 +/- 9.5 (p less than 0.01; 17.3% decrease from baseline), with no significant increase in days of abstinence. Neither 40 mg/day fluoxetine nor placebo had effects on intake of alcohol. Fluoxetine 60 mg/day decreased total and mean daily alcoholic drinks compared with 40 mg/day fluoxetine (ANCOVA, both p less than 0.02), but neither dose of fluoxetine was different from placebo. Compared with placebo, both 40 mg/day fluoxetine and 60 mg/day fluoxetine no differences were detected between treatment groups, 60 mg/day fluoxetine increased mean daily nonalcoholic beverages from baseline (5.0 +/- 0.4 to 5.6 +/- 0.3, p less than 0.01) and increased daily cigarettes smoked (from 25.1 +/- 4.6 to 26.9 +/- 4.5, p less than 0.05), whereas no significant changes from baseline were observed with 40 mg/day fluoxetine or placebo.(ABSTRACT TRUNCATED AT 250 WORDS)
Polylactones, 37. Polymerizations of <scp>L</scp>‐lactide initiated with Zn(II) <scp>L</scp>‐lactate and other resorbable Zn salts (1997)

Abstract Zn(II) L ‐lactate (ZnLac 2 ) was prepared either from ZnO and ethyl L ‐lactate or with slightly higher optical purity from ZnO and L ‐lactide. Using water‐free ZnLac 2 L ‐lactide was polymerized in bulk at 120°C or 150°C. Higher yields and higher molecular weights were found at 150°C. The highest number average molecular weights ( M̄ n around 70 000) were obtained at monomer/initiator (M/I) ratios of 4000. Despite the high reaction temperature the isolated poly( L ‐lactide)s were 100% optically pure. Analogous polymerizations were also conducted with Zn(II) L ‐mandelate or Zn(II) stearate with inferior results. Poor yields and molecular weights were found, when zinc glycolate salt was used as catalyst. Furthermore, numerous polymerizations were conducted with ZnCl 2 , ZnBr 2 or ZnI 2 as initiators. Again poly( L ‐lactide)s with 100% optical purity were isolated, but most molecular weights were lower and never higher than those obtained with ZnLac 2 . Therefore, ZnLac 2 proved to be the most favorable and fully resorbable (biocompatible) initiator of this study. Finally, the combination of ZnLac 2 with a primary alcohol, which plays the role of a coinitiator, allows a broad variation of the molecular weight and the introduction and modification of an ester endgroup. This approach also allows the incorporation of bioactive alcohols such as α‐tocopherol, stigmasterol or testosteron in the form of covalently bound ester endgroups.
Effect of Ammonia on the Growth of Carbon Nanotubes (2008)

Carbon nanotubes were grown on hydrogen-treated Fe catalyst at 700 degrees C using a thermal chemical vapor deposition method. During the growth, acetylene was used as the carbon source, which is balanced by hydrogen and/or ammonia. Raman analysis shows that the introduction of ammonia to the gaseous carbon source can lead to defect structures in the carbon nanotubes due to the incorporation of nitrogen atoms into the carbon nanotubes. Furthermore, the growth rate of carbon nanotubes was also affected by the introduction of ammonia into the gaseous carbon source. We show that the dependence of the growth rate on the gaseous source composition is better described in terms of the ratio of ammonia to acetylene than the overall ammonia concentration. It is proposed that there is a competition between the ammonia and the acetylene during the growth of CNTs. At low ammonia/acetylene ratios the growth increases with ammonia concentration; while at high ammonia/acetylene ratios the growth decreases with the ammonia concentration. A critical ammonia/acetylene ratio of 4.4, at which the growth peaks, was found and discussed.
Risk Factors for Fluconazole-Resistant Candida glabrata Bloodstream Infections (2009)

Previous fluconazole use is a significant risk factor for health care-associated fluconazole-resistant C glabrata BSIs. Future studies will be needed to evaluate the effect of decreasing fluconazole use on rates of fluconazole-resistant C glabrata BSIs.
Synthesis of Sulphones from Sulphonyl Fluorides and Organometallic Compounds (1978)

Abstract The reaction between sulphonyl fluorides and arylmagnesium bromides was investigated. The good yields of sulphones obtained demonstrates the potentialities of this reaction as a synthetic method for sulphones. Cadmium reagents were found to be unreactive toward the same sulphonyl fluorides.
Time Series Clustering of Electricity Demand for Industrial Areas on Smart Grid (2020)

This study forecasts electricity demand in a smart grid environment. We present a prediction method that uses a combination of forecasting values based on time-series clustering. The clustering of normalized periodogram-based distances and autocorrelation-based distances are proposed as the time-series clustering methods. Trigonometrical transformation, Box–Cox transformation, autoregressive moving average (ARMA) errors, trend and seasonal components (TBATS), double seasonal Holt–Winters (DSHW), fractional autoregressive integrated moving average (FARIMA), ARIMA with regression (Reg-ARIMA), and neural network nonlinear autoregressive (NN-AR) are used for demand forecasting based on clustering. The results show that the time-series clustering method performs better than the method using the total amount of electricity demand in terms of the mean absolute percentage error (MAPE).
570-ps 13-mW Josephson 1-kbit NDRO RAM (1989)

Josephson 1-kbit random access memories (RAM's) have been fabricated using Nb multilayer planarization technology with Nb/AlO/sub x//Nb junctions and Mo resistors. The RAM design has been reported previously. The RAM consists of a 32*32-bit nondestructive readout (NDRO) memory cell array and peripheral circuits. The NDRO memory cell consists of a loop storing three flux quanta and two 3-junction interferometer gates. The peripheral circuits consist of decoders with address inverters, drivers, a sense circuit and reset circuits, where resistor-coupled Josephson logic (RCJL) circuits are used as basic circuits. The RAM circuit size is 4.4*4.4 mm/sup 2/, and the memory cell size is 65*65 mu m/sup 2/. About 10000 Nb/AlO/sub x//Nb junctions with 1030-A/cm/sup 2/ critical current density were contained in the RAM. Minimum line and space widths were 3 and 2 mu m, respectively. The Mo resistors had 1.2 approximately 1.3 Omega sheet resistance. About 40 percent of the bits were successfully operated with a +or-18-percent bias margin. A minimum 570-ps access time with 13-mW power dissipation was obtained for the highest peripheral circuit bias conditions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Study of the Nd: Glass laser radiation (1970)

The Nd:glass laser has become one of the most useful sources of light pulses a few picoseconds in duration. In this paper, we review the results of an extensive study of the time and spectral structure of the Nd:glass laser radiation. The time structure was studied by means of two-photon fluorescence (TPF) patterns: these were scanned by a very thin (28-μ) cell containing the fluorescent dye, the fluorescence being monitored by a photomultiplier. When the Nd:glass laser is <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> switched by a rotating mirror or when it is free running, we find TPF patterns fully consistent with a model where the laser emission has the character of Gaussian noise (thermal light), i.e., a model where the modes are randomly phased. When the laser was simultaneously <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> switched and mode locked we made two observations : 1) the TPF patterns show that the ultra-short pulses observed previously have an overall duration of ∼8 ps, but also possess an internal substructure containing peaks 0.4-0.8 ps in duration; 2) the spectral width of these pulses is <20 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> at the beginning of the <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> -switched train and expands to ∼80 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> in the middle of the train. This rapid spectral broadening during pulse buildup is attributed to self-phase modulation in the laser glass matrix due to a nonlinear index n <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> which we evaluate as <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n{2}= (2 \pm 1) \times 10^{-22}</tex> m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> /V <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (or <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1.8 \times 10^{-13}</tex> esu). Gain limiting due to this effect and self-focusing become very important at power densities above 1 GW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , presenting a serious limitation on the energy density (J/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ), which one may hope to extract from Nd: glass laser systems.
Male Breast Cancer (2017)

This is a contemporary review of risk factors and genetic predisposition associated with breast cancer in men. The workup and evaluation of breast masses and surgical management of cancer in this population are detailed. In addition, systemic therapies for the treatment of breast cancer in men are reviewed and compared with the therapeutic approaches used for women. This reviews contains 5 figures, 2 tables and 50 references. Key words: breast-conserving surgery, chemotherapy, endocrine therapy, genetic predisposition testing, genomic profiling, lymphadenectomy, male breast cancer, mastectomy, radiotherapy, sentinel lymph node biopsy
NEUROPLASTICITE, NEUROGENESE ET DEPRESSION: CONSIDÉRATIONS CLINIQUES (2009)

peer reviewed
US&R: A New Framework for Redoing (1984)

Undo, Skip, & Redo-a new interactive approach to user recovery offers significant advantages over current undo/redo packages.
Estimating structured high-dimensional covariance and precision matrices: Optimal rates and adaptive estimation (2016)

This is an expository paper that reviews recent developments on optimal estimation of structured high-dimensional covariance and precision matrices. Minimax rates of convergence for estimating several classes of structured covariance and precision matrices, including bandable, Toeplitz, sparse, and sparse spiked covariance matrices as well as sparse precision matrices, are given under the spectral norm loss. Data-driven adaptive procedures for estimating various classes of matrices are presented. Some key technical tools including large deviation results and minimax lower bound arguments that are used in the theoretical analyses are discussed. In addition, estimation under other losses and a few related problems such as Gaussian graphical models, sparse principal component analysis, factor models, and hypothesis testing on the covariance structure are considered. Some open problems on estimating high-dimensional covariance and precision matrices and their functionals are also discussed.
Ergebnisse (1972)

Den Beobachtungen des Verhaltens der Kinder beider Gruppen während des Trainings bzw. während der Beschäftigung der Kontrollgruppe wurde große Bedeutung beigemessen, da dieses zur Interpretation der Ergebnisse des Trainingsexperimentes beitragen und Hinweise auf störende Einflüsse geben konnte. Die Beobachtungen werden für die Kinder der Trainings- und der Kontrollgruppe getrennt kurz beschrieben.
Postoperative Complications Following Surgery for Rectal Cancer (2010)

Benchmark complication rates for radical rectal cancer surgery were obtained for use in sample size calculations in future studies and for quality control purposes. Postoperative death rates showed improvement in recent years.
Transversal Filter Design and Application in Satellite Communications (1976)

A brief literature survey of transversal filters is followed by a design example of a binary transversal filter. A particular application in the modulator of the single channel per carrier data transmission equipment is described. Computer simulations and COS/MOS hardware implementation proved the validity and the feasibility of the theory described by Mueller. Design and evaluation of a linear phase filter approaching the Nyquist channel is the end result of our study.
Catalytic epoxidation of propene with H2O–O<sub>2</sub>reactants on Au/TiO<sub>2</sub> (2008)

Au/TiO2catalysts form hydroperoxy species from H2O–O2 mixtures at near-ambient temperatures; these species can be used in the selective epoxidation of propene to propylene oxide.
LA CERÁMICA DE IMPORTACIÓN DE LA NECRÓPOLIS DE LA ALBUFERETA, ALICANTE (1975)

Revista especializada en la publicación de trabajos originales de investigación en Prehistoria y Arqueología. Es la publicación periódica más antigua de la UAM. Su enfoque abierto a cualquier temática y época pasada, hasta la más cercana, que sea objeto de la Ciencia arqueológica se abre a una decidida proyección internacional en la que quiere basar su futuro inmediato.
Comparison of mutagenicity results for nine compounds evaluated at the <i>hgprt</i> locus in the standard and suspension CHO assays (1991)

The Chinese hamster ovary (CHO) assay, which measures newly induced mutations at the hypoxanthine-guanine phosphoribosyltransferase (hgprt) locus, has been widely used for mutagenesis testing. The insensitivity of the standard assay to some genotoxic agents has been speculated to be due to the relatively small number of cells used in the assay. In the present study, we have compared the standard monolayer assay with a suspension adapted CHO assay that uses cell numbers comparable to that of the L5178Y mouse lymphoma assay. Nine compounds, ethyl methanesulfonate (EMS), methyl methanesulfonate (MMS), 2-methoxy-6-chloro-9-[3-(ethyl-2-chloroethyl)-aminopropylamino]-acridine 2HCl (ICR 170), methyl acrylate, ethyl acrylate, tetraethylene glycol diacrylate, trimethylolpropane triacrylate, 2-ethylhexyl acrylate and dicyclopentenyloxyethyl methacrylate were evaluated in the monolayer and suspension assays. Both assays gave the same overall qualitative results for the test compounds. There were some quantitative differences in the mutant frequency for the three compounds found to be mutagenic (EMS, MMS and ICR 170). The acrylates (many of which appear to exert their genotoxic effect through a clastogenic mechanism) were negative in both test systems. The use of the suspension assay did not improve the ability of the hgprt locus to detect the genotoxicity of the acrylates. Thus, increasing the number of cells does not improve the ability of the CHO/HGPRT assay to detect compounds that act primarily by a clastogenic mechanism.
Computer-aided detection of prostate cancer in T2-weighted MRI within the peripheral zone (2016)

In this paper we propose a prostate cancer computer-aided diagnosis (CAD) system and suggest a set of discriminant texture descriptors extracted from T2-weighted MRI data which can be used as a good basis for a multimodality system. For this purpose, 215 texture descriptors were extracted and eleven different classifiers were employed to achieve the best possible results. The proposed method was tested based on 418 T2-weighted MR images taken from 45 patients and evaluated using 9-fold cross validation with five patients in each fold. The results demonstrated comparable results to existing CAD systems using multimodality MRI. We achieved an area under the receiver operating curve (A z ) values equal to [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] for Bayesian networks, ADTree, random forest and multilayer perceptron classifiers, respectively, while a meta-voting classifier using average probability as a combination rule achieved [Formula: see text].