gebhart/patrepeval huggingface dataset:
Effect of condensed tannin on protein digestion and nutritive value of fresh herbage. (1990)

Condensed tannins (CT) are polymeric flavanols that occur in a variety of plants including lotus, sainfoin, dock and mulga. CT are not toxic to ruminants, and when the concentration is below about 4% of dry matter (DM), they improve the nutritive value of herbage by binding to plant proteins and protecting them from excessive degradation in the rumen. The percentage absorption from the intestine is reduced, but the net effect of CT is to increase the amount of essential amino acids (AA) absorbed by 20-50% compared to plants without CT. Sheep fed herbage containing CT have an increased absorption of sulphur-AA which should increase wool production, have leaner carcasses, and CT prevent bloat in cattle.
Front Cover: Building proteomic tool boxes to monitor MHC class I and class II peptide (2017)

DOI: 10.1002/pmic.201600061 MHCI and MHCII peptides are presented on the surface of all nucleated cells in mammals and provide the immune system with a mechanism to recognize both intracellular and extracellular proteins. Over the past few decades' researchers have characterized MHC presented peptide sequences and their relative abundance on the cell surface of malignant, virally infected and “normal” cells. These insights have enabled the development of various T cell mediated therapeutic strategies and, allowed researchers to monitor fluctuations in MHCI and MHCII peptides in response to disease etiology and drug treatment. This review discusses these topics with a focus on profiling MHC presented peptides to aid T cell mediated biotherapeutic development. For more details, see the review by Frances-Rose Schumacher et al. (https://doi.org/10.1002/pmic.201600061).
[Effects of carbon monoxide inhalation on severe limb ischemia/reperfusion injury and its damages lead to shock]. (2011)

Inhaling exogenous low-dose CO has a reverse regulation in the blood pressure decline caused by serious limb I/R injury in rats. And at the same time, it can effectively prevent the occurrence of shock, reduce physical damage, significantly increase the survival rate of animals.
Quantum-secure covert communication on bosonic channels (2015)

Computational encryption, information-theoretic secrecy and quantum cryptography offer progressively stronger security against unauthorized decoding of messages contained in communication transmissions. However, these approaches do not ensure stealth--that the mere presence of message-bearing transmissions be undetectable. We characterize the ultimate limit of how much data can be reliably and covertly communicated over the lossy thermal-noise bosonic channel (which models various practical communication channels). We show that whenever there is some channel noise that cannot in principle be controlled by an otherwise arbitrarily powerful adversary--for example, thermal noise from blackbody radiation--the number of reliably transmissible covert bits is at most proportional to the square root of the number of orthogonal modes (the time-bandwidth product) available in the transmission interval. We demonstrate this in a proof-of-principle experiment. Our result paves the way to realizing communications that are kept covert from an all-powerful quantum adversary.
Biomechanical Evaluation of Arthroscopic Rotator Cuff Repairs (2006)

In this in vitro cadaver study, double-row fixation had a significantly higher ultimate tensile load than the three types of single-row fixation stitches. Of the single-row fixations, the massive cuff stitch had cyclic and load-to-failure characteristics similar to the double-row fixation. Anterior repairs of the supraspinatus tendon had significantly stronger biomechanical behavior than posterior repairs.
Gas Adsorption Study on Mesoporous Metal−Organic Framework UMCM-1 (2010)

A mesoporous metal−organic framework (MOF) material, UMCM-1, has been synthesized and characterized using N2 adsorption, powder X-ray diffraction, scanning electron microscopy, and Fourier transform infrared techniques. A detailed experimental study has been made of the adsorption of pure methane, hydrogen, carbon dioxide, oxygen, and nitrogen at various temperatures (298−338 K) and pressures (up to 25 bar). Multitemperature isotherms were modeled using the Dubinin−Astakhov equation to obtain useful thermodynamic properties including adsorption potential characteristic curves and isosteric heats of adsorption. Results are compared with mesoporous carbons and silicas. Large-pore materials are shown to exhibit relatively high heats of adsorption for CO2 when open metal sites are present. This phenomenon is not observed for methane, which indicates the importance of the CO2 quadrupole in influencing binding strength. Adsorption results for N2 and O2 show that selectivities in MOFs can be manipulated by the presence or absence of open metal sites. UMCM-1 and MOF-177 show a slight preference for O2 over N2. However, open metal site MOFs such as Cu-BTC show the opposite adsorption preference, which is similar to zeolite selectivities. This experimental study reveals interesting adsorption information about a novel mesoporous MOF within the context of other MOFs and traditional mesoporous adsorbents. These results can be used to advance the development of structure−property relationships for metal−organic frameworks.
Tn5 insertion mutations in the mercuric ion resistance genes derived from plasmid R100 (1983)

The mercuric resistance (mer) genes of plasmid R100 were cloned into plasmid pBR322. A series of transposon Tn5 insertion mutations in the mer genes were isolated and mapped. The mutants were characterized phenotypically by their sensitivity to Hg2+ and by binding and volatilization of 203Hg2+. Dominance and complementation tests were also performed. Mutations affecting the previously described mer genes merR (regulation), merT (transport), and merA (reductase) were characterized. Evidence was obtained for two new mer genes, which have been called merC and merD. A restriction enzyme map of the mer region was drawn with the gene order merRTCAD. Transcriptional merR-lac and merA-lac fusions were generated by insertion of phage Mu d amp lac into plasmid R100-1. These were used to study regulation of mer gene expression. The merR gene product appears to regulate negatively its own expression as well as acting as both a negative and a positive regulator of the merTCA genes.
Tracer design for magnetic particle imaging (invited) (2012)

Magnetic particle imaging (MPI) uses safe iron oxide nanoparticle tracers to offer fundamentally new capabilities for medical imaging, in applications as vascular imaging and ultra-sensitive cancer therapeutics. MPI is perhaps the first medical imaging platform to intrinsically exploit nanoscale material properties. MPI tracers contain magnetic nanoparticles whose tunable, size-dependent magnetic properties can be optimized by selecting a particular particle size and narrow size-distribution. In this paper we present experimental MPI measurements acquired using a homemade MPI magnetometer: a zero-dimensional MPI imaging system designed to characterize tracer performance by measuring the derivative of the time-varying tracer magnetization, M'(H(t)), at a driving frequency of 25 kHz. We show that MPI performance is optimized by selecting phase-pure magnetite tracers of a particular size and narrow size distribution; in this work, tracers with 20 nm median diameter, log-normal distribution shape parameter, σ(v), equal to 0.26, and hydrodynamic diameter equal to 30 nm showed the best performance. Furthermore, these optimized MPI tracers show 4 × greater signal intensity (measured at the third harmonic) and 20% better spatial resolution compared with commercial nanoparticles developed for MRI.
Using network flows in hierarchical QoS routing (2005)

Quality of Service (QoS) routing is the process of routing a connection through a network based on its resource requirements. In QoS routing a lot of overhead is generated either due to the state maintenance or during the call establishment. These overheads increase with the network size. Hence to deploy QoS routing in very big networks, special techniques for reducing these overheads have to be developed. State aggregation is an important technique for reducing the state maintenance overhead. In state aggregation, each domain constructs an aggregated topology of itself, and sends it to other domains. Other domains make routing decisions based on this aggregated information. However, as the network resources change dynamically, the information sent by a domain quickly becomes out-of-date. This stale information leads to bad routing decisions and hence the routing performance goes down. If a domain can update the aggregated information sent by other domains, better routing decisions can be made and hence the routing performance can improve. In this paper, based on "network flows", we propose a new scheme for aggregating bandwidth. Our scheme enables a domain to update the aggregate sent by another domain and thus keep track of resources available in other domains. We also give a distributed approach for inter-domain routing based on our proposed aggregation scheme. Simulation results show that our method gives a better bandwidth admission ratio when compared to existing aggregation techniques.
Renal actions of angiotensin-(1-7): in vivo and in vitro studies (1996)

In vivo studies were conducted in Na-replete anesthetized male Wistar rats with denervated kidneys. Intrarenal injections of angiotensin-(1-7) [ANG-(1-7) at > 1 nmol/kg produced a shallow dose-dependent decrease in renal blood flow that was mediated by the AT1-type ANG II receptor. A constant intrarenal infusion of ANG-(1-7) at 0.1 and 1 nmol.min-1.kg-1 had minimal effects on renal blood flow and blood pressure and resulted in an elevated urinary excretion of Na and water compared with the time-control saline-infused group. To determine whether ANG-(1-7) may have a direct action on tubular epithelium to inhibit Na reabsorption, we examined the effect of ANG-(1-7) on transport-dependent O2 consumption (Qo2) in fresh suspensions of rat proximal tubules in vitro. ANG-(1-7) inhibited Qo2 in a concentration-dependent fashion with a threshold concentration of approximately 100 pM. Stimulating Na-K-adenosinetriphosphatase (Na-K-ATPase) activity with nystatin caused a leftward shift of the inhibitory concentration-response curve to ANG-(1-7). The 22% inhibition of Qo2 by 1 pM ANG-(1-7) was abolished by pretreatment with 5 mM ouabain (Na-K-ATPase inhibitor), unaltered by pretreatment with 1 microM PD-123319 (AT2 receptor antagonist), partially attenuated by 1 microM losartan (AT1 receptor antagonist), and abolished by 1 microM [Sar1, Thr8]ANG II (nonselective ANG receptor antagonist). Together these findings indicate that ANG-(1-7) has biological activity in the kidney and, at nonvasoconstrictor doses, results in increased Na and water excretion in vivo. One site of action is the proximal tubule, where ANG-(1-7) can inhibit an ouabain-sensitive Na-K-ATPase exit step in cellular Na transport. This novel inhibitory action of ANG-(1-7) appears to be mediated by an AT1 receptor (minor component) and a non-AT1, non-AT2 ANG receptor (major component).
Tailoring properties of carbon-nanotube-based foams by ion bombardment (2012)

Particle irradiation is an effective method for manipulating properties of individual carbon nanotubes (CNTs). This potential, however, remains unexplored for macroscopic assemblies of cross-linked CNTs. Here, we study structural and electrical properties of ultralow-density cross-linked CNT-based nanofoams exposed to ion irradiation at room temperature over a wide range of ion masses and fluences. For all irradiation conditions studied, the electrical resistance of nanofoams initially increases with a rate that scales with the number of ballistically generated displacements. This process is attributed to the buildup of defects in graphitic nanoligaments. Irradiation with Ne and heavier ions leads to a decrease in the electrical resistance at large fluences, which is attributed to radiation-induced foam densification. In addition, heavy-ion bombardment causes amorphization of CNTs and smoothing of ligament surfaces. These results demonstrate that ion bombardment can be used for tailoring density, ligament morphology, and electrical properties of CNT-based foams.
An Evaluation of Molten-Salt Power Towers Including Results of the Solar Two Project (2001)

This report utilizes the results of the Solar Two project, as well as continuing technology development, to update the technical and economic status of molten-salt power towers. The report starts with an overview of power tower technology, including the progression from Solar One to the Solar Two project. This discussion is followed by a review of the Solar Two project--what was planned, what actually occurred, what was learned, and what was accomplished. The third section presents preliminary information regarding the likely configuration of the next molten-salt power tower plant. This section draws on Solar Two experience as well as results of continuing power tower development efforts conducted jointly by industry and Sandia National Laboratories. The fourth section details the expected performance and cost goals for the first commercial molten-salt power tower plant and includes a comparison of the commercial performance goals to the actual performance at Solar One and Solar Two. The final section summarizes the successes of Solar Two and the current technology development activities. The data collected from the Solar Two project suggest that the electricity cost goals established for power towers are reasonable and can be achieved with some simple design improvements.
Detection of Oseltamivir Resistance during Treatment of 2009 H1N1 Influenza Virus Infection in Immunocompromised Patients: Utility of Cycle Threshold Values of Qualitative Real-Time Reverse Transcriptase PCR (2010)

Two immunocompromised patients with 2009 H1N1 influenza pneumonia had viral shedding for over 5 weeks despite therapy with oseltamivir. Declining or persistently low cycle threshold values noted on serial qualitative real-time reverse transcriptase PCR (rRT-PCR) of respiratory specimens implied increasing viral load and probable drug resistance. Oseltamivir resistance was later confirmed by pyrosequencing.
Deblending 4-component simultaneous-source data – A 2D OBC case study in Malaysia (2015)

Summary In ocean-bottom cable (OBC) acquisitions, a significant part of the survey time is dedicated to source shooting. Simultaneous-source shooting, which allows time overlaps between shots, paves the way for an increase in acquisition productivity or better wavefield sampling (Hampson et al., 2008). However, blended datasets require specific treatment before being processed using conventional techniques (Davies et al., 2013). In this paper, we present the deblending work carried out on a blended 2D 4-component (4C) OBC shallow water dataset acquired in Malaysia with time dithering between sources. The deblending flow, based on a combination of iterative signal extraction and impulsive and interference noise attenuation, is described together with the QC procedures performed prior to migration. This flow is designed to tackle the deblending of both compressional and converted waves.
(<i>Z</i>)‐Selective Partial Hydrogenation of Internal Alkynes by Using Palladium Nanoparticles Supported on Nitrogen‐Doped Carbon Nanofiber (2012)

Doing things by half: Palladium nanoparticles supported on the nitrogen-doped carbon nanofiber (Pd/N-CNF-H) are synthesized by thermally decomposing Pd2(dba)3⋅CHCl3 in toluene in the presence of N-CNF-H, and act as efficient catalysts for the partial hydrogenation of internal alkynes to the corresponding (Z)-alkenes in high turnover numbers.
Metallic Braided Structures: The Mechanical Modeling (2015)

In this paper, the mechanical behavior of braided metallic structures used in the pipe industry was investigated in both ways numerically and experimentally in order to find the cheapest and the most accurate way to simulate their complex behavior. Therefore, two experimental tests were established to show the tension and the pressure expansion behaviors, then, several finite element approaches were developed and compared with the experiment, which are: a micro‐scale model where each metallic wire is considered as an independent three‐dimensional structure, a meso‐scale model where each group of wires was modeled as a continuum material with equivalent mechanical behavior, and a macro‐scale model where the whole structure is considered as a fully homogeneous material. And it is shown that the homogenization is more suitable for small displacements but for complex behaviors the meso‐ and the micro‐scale models are more reliable.
Correction - Absorption of Gases in Spray Towers (1935)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCorrection - Absorption of Gases in Spray TowersA. Hinson and C. ScottCite this: Ind. Eng. Chem. 1935, 27, 6, 665Publication Date (Print):June 1, 1935Publication History Published online13 December 2004Published inissue 1 June 1935https://pubs.acs.org/doi/10.1021/ie50306a600https://doi.org/10.1021/ie50306a600research-articleACS PublicationsRequest reuse permissionsArticle Views19Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
WiFi attack vectors (2005)

The security risks of WiFi connectivity have been established---the reasons for these risks of intrusion are not as well understood.
CONTRASTING EFFECTS OF ISOPROTERENOL AND PHOSPHODIESTERASE I11 INHIBITOR ON INTRACELLULAR CALCIUM TRANSIENTS IN CARDIAC MYOCYTES FROM FAILING HEARTS (1994)

1. Effects of a newly developed phosphodiesterase (PDE) III inhibitor, E-1020, on intracellular calcium transients were compared with those of isoproterenol (ISO) in isolated single myocytes from failing hearts secondary to pulmonary hypertension induced by monocrotaline injection. Myocytes were isolated by enzyme digestion using a Langendorff apparatus. Changes in intracellular calcium concentrations ([Ca2+]i) were recorded using a fura-2 fluorescence microscopic technique. Cyclic AMP contents of the hearts were measured by radio-immunoassay. 2. Myocytes from failing hearts showed Ca2+ transients with a low peak (low amplitude) and delayed decline of Ca2+ transients. Both ISO and E-1020 increased peak [Ca2+]i, max + d[Ca2+]i/dt, and max - d[Ca2+]i/dt in a concentration-dependent manner while both agents decreased T80L (time to 80% decline of amplitude from peak light). The concentrations which increased peak [Ca2+]i by 50% were 1.6 x 10(-9) mol/L of ISO and 2 x 10(-6) mol/L of E-1020. These concentrations increased cAMP in the heart to the same levels. Analysis of the effects of both agents on peak [Ca2+]i versus max - d[Ca2+]i/dt showed that ISO is much more effective on peak [Ca2+]i while E-1020 is more effective on max - d[Ca2+]i/dt. 3. These results showed that the effects of ISO and E-1020 on the parameters of intracellular Ca2+ transients of single myocytes from failing hearts are slightly different, and suggest that E-1020 may improve diastolic function as well as systolic function in failing hearts.
A surface micromachined amorphous Ge x Si 1-x O y bolometer for thermal imaging applications (2004)

We present characterization of a surface micro-machined microbolometer featuring a number of unique features. The active resistor layer is amorphous Ge<sub>x</sub>Si<sub>1-x</sub>O<sub>y</sub> grown by reactively co-sputtering Ge and Si in an oxygen background. Complete control over Ge, Si, and O content using this technique allows control of both temperature coefficient of resistance and resistivity of the material, enabling optimization of material characteristics for bolometer applications. The resistor layer is combined with top and bottom NiCr metalization to form a tuned absorber for 10 μm radiation, eliminating requirements for additional absorber layers or for carefully controlled air gap thickness. Characterization of device noise and performance is presented.
CB<sub>2</sub>-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion (2007)

Targeting cannabinoid-2 (CB(2)) receptors with selective agonists may represent a novel therapeutic avenue in various inflammatory diseases, but the mechanisms by which CB(2) activation exerts its anti-inflammatory effects and the cellular targets are elusive. Here, we investigated the effects of CB(2)-receptor activation on TNF-alpha-induced signal transduction in human coronary artery endothelial cells in vitro and on endotoxin-induced vascular inflammatory response in vivo. TNF-alpha induced NF-kappaB and RhoA activation and upregulation of adhesion molecules ICAM-1 and VCAM-1, increased expression of monocyte chemoattractant protein, enhanced transendothelial migration of monocytes, and augmented monocyte-endothelial adhesion. Remarkably, all of the above-mentioned effects of TNF-alpha were attenuated by CB(2) agonists. CB(2) agonists also decreased the TNF-alpha- and/or endotoxin-induced ICAM-1 and VCAM-1 expression in isolated aortas and the adhesion of monocytes to aortic vascular endothelium. CB(1) and CB(2) receptors were detectable in human coronary artery endothelial cells by Western blotting, RT-PCR, real-time PCR, and immunofluorescence staining. Because the above-mentioned TNF-alpha-induced phenotypic changes are critical in the initiation and progression of atherosclerosis and restenosis, our findings suggest that targeting CB(2) receptors on endothelial cells may offer a novel approach in the treatment of these pathologies.
Two Mechanistically and Temporally Distinct NF-κB Activation Pathways in IL-1 Signaling (2009)

The cytokine interleukin-1 (IL-1) mediates immune and inflammatory responses by activating the transcription factor nuclear factor kappaB (NF-kappaB). Although transforming growth factor-beta-activated kinase 1 (TAK1) and mitogen-activated protein kinase (MAPK) kinase kinase 3 (MEKK3) are both crucial for IL-1-dependent activation of NF-kappaB, their potential functional and physical interactions remain unclear. Here, we showed that TAK1-mediated activation of NF-kappaB required the transient formation of a signaling complex that included tumor necrosis factor receptor-associated factor 6 (TRAF6), MEKK3, and TAK1. Site-specific, lysine 63-linked polyubiquitination of TAK1 at lysine 209, likely catalyzed by TRAF6 and Ubc13, was required for the formation of this complex. After TAK1-mediated activation of NF-kappaB, TRAF6 subsequently activated NF-kappaB through MEKK3 independently of TAK1, thereby establishing continuous activation of NF-kappaB, which was required for the production of sufficient cytokines. Therefore, we propose that the cooperative activation of NF-kappaB by two mechanistically and temporally distinct MEKK3-dependent pathways that diverge at TRAF6 critically contributes to immune and inflammatory systems.