gebhart/patrepeval huggingface dataset:
Stationary Subdivision and Multiresolution Surface Representations (1997)

Stationary subdivision is an important tool for generating smooth free-form surfaces used in CAGD and computer graphics. One of the challenges in the construction of subdivision schemes for arbitrary meshes is to guarantee that the surfaces produced by the algorithm are $C\sp1$-continuous. First results in this direction were obtained only recently. In this thesis we derive necessary and sufficient criteria for $C\sp{k}$-continuity that generalize and extend most known conditions.
We present a new method for analysis of smoothness of subdivision which allows us to analyze subdivision schemes which do not generate surfaces admitting closed-form parameterization on regular meshes, such as the Butterfly scheme and schemes with modified rules for tagged edges.
The theoretical basis for analysis of subdivision that we develop allows us to suggest methods for constructing new subdivision schemes with improved behavior. We present a new interpolating subdivision scheme based on the Butterfly scheme, which generates $C\sp1$-continuous surfaces from arbitrary meshes.
We describe a multiresolution representation for meshes based on subdivision. Combining subdivision and the smoothing algorithms of Taubin, allows us to construct a set of algorithms for interactive multiresolution editing of complex hierarchical meshes of arbitrary topology.
Molecular biology of the Chlamydia pneumoniae surface. (1997)

Chlamydia pneumoniaeis a fastidious microorganism with a characteristic biphasic lifecycle causing a variety of human respiratory tract infections. There is limited knowledge about the molecular biology of C. pneumoniae, and only a few genes have been sequenced. The structure of the chlamydial surface differs from that of Chlamydia trachomatis. In order to study the surface of C. pneumoniae we generated monoclonal antibodies (MAbs) against C. pneumoniae strain VR-1310 and selected 14 MAbs that reacted with the surface of C. pneumoniae. All MAbs reacted in immunoelectron microscopy with the surface of both whole C. pneumoniae VR-1310 elementary bodies and with purified sarcosyl extracted outer membrane complexes. However, only 2 of the MAbs reacted in immunoblotting with C. pneumoniae proteins and only with antigen that had not been heat treated in SDS-sample buffer. This indicates the dominance of conformational epitopes at the C. pneumoniae surface.
Tough, Semiconducting Polyethylene‐poly(3‐hexylthiophene) Diblock Copolymers (2007)

Abstract Semiconducting diblock copolymers of polyethylene (PE) and regioregular poly(3‐hexylthiophene) (P3HT) are demonstrated to exhibit a rich phase behaviour, judicious use of which permitted us to fabricate field‐effect transistors that show saturated charge carrier mobilities, μ FET , as high as 2 × 10 –2 cm 2 V –1 s –1 and ON‐OFF ratios, I on / I off ∼ 10 5 at contents of the insulating PE moiety as high as 90 wt %. In addition, the diblock copolymers display outstanding flexibility and toughness with elongations at break exceeding 600 % and true tensile strengths around 70 MPa, opening the path towards robust and truly flexible electronic components.
One‐Pot Synthesis of Manganese Oxide Nanosheets in Aqueous Solution: Chelation‐Mediated Parallel Control of Reaction and Morphology (2007)

Miniblätter mit Struktur: Manganoxid-Nanoblättchen und orientierte dünne Filme dieser Materialien sind die Produkte einer „Bottom-up“-Synthese in wässriger Lösung unter Umgebungsbedingungen (links). Die Chelatisierung von Manganspezies und Ethylendiamintetraacetat(EDTA)-Liganden führt zu Nanoblättchen mit Birnessit-Struktur (Mikroskopie- und Röntgenbeugungsbilder). Bei dieser biomimetischen Route werden sowohl die Synthesereaktion als auch die Morphogenese durch das chelatisierende Agens EDTA gesteuert. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2007/z700244_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
APPENDIX III Genes of Saccharomyces cerevisiae (1981)

This Appendix provides information on identified and characterized yeast genes. The core of this information is presented in part A, which is an alphabetical listing of all gene designations, providing for each designation any former or alternate designations, the phenotype of a strain containing a mutation in that gene, the gene product (if known), the map position (if known), and an appropriate literature reference. In addition, the information in part A has been extracted and indexed in alternative formats in parts B and C. Part B is an alphabetical listing of all gene products given in part A, providing each with the corresponding gene designation. Thus, one can readily find, for example, that the gene encoding phosphoglycerate mutase is designated GPM1. To determine the phenotype of strains lacking phosphoglycerate mutase, one can then refer to part A under GPM1. In Part C, the genes listed in part A are grouped by common function. For convenience, a list of categories by which the genes are grouped is provided on the first page of part C. The genes involved in each category follow. The listings are not exclusive; a particular gene may appear in several categories. There are four sources of information provided in this Appendix. The authors of the various chapters have been of prime importance. Thus, much of the information has been extracted directly from individual chapters. Our second source was responses from a mass mailing to the yeast community, conducted in the Spring of 1980, in which we requested...
Early Hemoperfusion May Improve Survival of Severely Paraquat-Poisoned Patients (2012)

The results showed that early HP after PQ exposure might be effective in reducing mortality in severely poisoned patients, particularly in those treated with repeated pulse therapy.
Further Studies With Topical 5-Fluorouracil (1965)

Actinic keratoses were treated with an ointment containing a 1%, 2.5%, or 5% concentration of 5-fluorouracil. The response with the 5% ointment was comparable to our original studies with 20% 5-fluorouracil ointment. The 1% and 2.5% concentrations were found ineffective. Topical application of 5-fluorouracil labeled with radioactive carbon (<sup>14</sup>C) in five patients indicated that approximately 6% is absorbed systemically. These data along with repeated hematologic studies suggest that 5-fluorouracil ointment applied to limited skin areas is not absorbed in a degree that would produce general toxicity. We have concluded that 5% 5-fluorouracil ointment applied twice daily can be used as an effective outpatient treatment in the person with numerous actinic keratoses of the face and neck. Prolonged observation will be required to assess the long term results of this treatment. Actinic keratoses on the hands and arms have not responded completely enough to justify this type of treatment. One must avoid applications near the lid margins and mucocutaneous junctions. A phototoxic reaction precluded the ointments use when the patient anticipated prolonged sunlight exposure.
Wafer Level Packaging of Compound Semiconductors (2010)

The microelectronics industry has implemented a number of different wafer level packaging (WLP) technologies for high volume manufacturing, including: UBM deposition, solder bumping, wafer thinning, and dicing. These technologies were successfully developed and implemented at a number of contract manufacturing companies, and then licensed to many of the semiconductor manufacturers and foundries. The largest production volumes for these technologies are for silicon-based semiconductors. Continuous improvements and modifications to these WLP processes have made them compatible with the changes observed over the years in silicon semiconductor technologies. These industry changes include: the move from aluminum to copper interconnect metallurgy, increases in wafer size, decreases in pad pitch, and the use of Low-K dielectrics. In contrast, the direct transfer of these WLP technologies to compound semiconductor devices, like GaAs, SiC, InP, GaN, and sapphire; has been limited due to a number of technical compatibility issues, several perceived compatibility issues, and some business concerns From a technical standpoint, many compound semiconductor devices contain fragile air bridges, gold bond pads, topographical cavities and trenches, and have a number of unique bulk material properties which are sensitive to the mechanical and chemical processes associated with the standard WLP operations used for silicon wafers. In addition, most of the newer contract manufacturing companies and foundries have implemented mostly 200 and 300 mm wafer capabilities into their facilities. This limits the number of places that one can outsource the processing of 100 and 150 mm compound semiconductor wafers. Companies that are processing large numbers of silicon based semiconductor wafers at their facilities are reluctant to process many of these compound semiconductors because there is a perceived risk of cross contamination between the different wafer materials. Companies are not willing to risk their current business of processing silicon wafers by introducing these new materials into existing process flows. From a business perspective, many companies are reluctant to take the liability risks associated with some of the very high-value compound semiconductors. In addition, the volumes for many of the compound semiconductor devices are very small compared with silicon based devices, thus making it hard to justify interruption in the silicon wafer flows to accommodate these lower volume products. In spite of these issues and perceptions, the markets for compound semiconductors are expanding. Several high profile examples include the increasing number of frequency and power management devices going into cell phones, light emitting diodes, and solar cells The strategy for the work described in this paper is to protect all structures and surfaces with either a spin-on resist or a laminated film during each step in the process flow. These layers will protect the wafer from mechanical and chemical damage, and at the same time protect the fab from contamination by the compound semiconductor.
On Transcoding a B-Frame to a P-Frame in the Compressed Domain (2007)

Only a limited number of methods have been proposed to realize heterogeneous transcoding, for example from MPEG-2 to H.263, or from H.264 to H.263. The major difficulties of transcoding a B-picture to a P-picture are that the incoming discrete cosine transform (DCT) coefficients of the B-frame are prediction errors arising from both forward and backward predictions, whilst the prediction errors in the DCT domain arising from the prediction using the previous frame alone are not available. The required new prediction errors need to be re-estimated in the pixel domain. This process involves highly complex computation and introduces re-encoding errors. We propose a new approach to convert a B-picture into a P-picture by making use of some properties of motion compensation in the DCT domain and the direct addition of DCT coefficients. We derive a set of equations and formulate the problem of how to obtain the DCT coefficients. One difficulty is that the last P-frame inside a GOP with an IBBP structure, for example, needs to be transcoded to become the last P-frame in the IPPP structure, and it has to be linked to the previous reconstructed P-frame instead of to the I-frame. We increased the speed of the transcoding process by making use of the motion activity which is expressed in terms of the correlation between pictures. The whole transcoding process is done in the transform domain, hence re-encoding errors are completely avoided. Results from our experimental work show that the proposed video transcoder not only achieves a speed-up of two to six times that of the conventional video transcoder, but it also substantially improves the quality of the video.
Agonist-induced production of 1,2-diacylglycerol and phosphatidic acid in intact resistance arteries. Evidence that accumulation of diacylglycerol is not a prerequisite for contraction. (1990)

The production of total amounts of 1,2-diacylglycerol as well as those specifically derived from inositol lipid hydrolysis was studied in intact rat resistance arteries stimulated with either noradrenaline, vasopressin, or angiotensin II at 20 s when the onset of contraction would be nearing its maximum, and at 5 min during the sustained phase of contraction. Total amounts of 1,2-diacylglycerol were not altered by any agonist at 20 s, or at 5 min. However, arachidonate-containing species of 1,2-diacylglycerol were differentially influenced being increased at 5 min by noradrenaline, and decreased at 20 s and 5 min by vasopressin. Only angiotensin II produced substantial increases in this class of 1,2-diacylglycerol at both time points. In order to investigate the fate of this second messenger total and inositol lipid derived phosphatidic acids were then measured at both 20 s and 5 min. Noradrenaline induced a rise in both total and arachidonate-containing phosphatidic acid at both times as did vasopressin. Only small increases were induced by angiotensin II at 20 s. These data demonstrate that the accumulation of 1,2-diacylglycerol generated from inositol lipid breakdown is only observed with activation by angiotensin II. Other agonists produced phosphatidic acids with time and the rate of generation of these lipids is agonist-specific. Thus phosphatidic acid may play a more prominent role during the sustained phase of contraction than previously anticipated.
Lipophilic analogs of sparsomycin as strong inhibitors of protein synthesis and tumor growth: a structure-activity relationship study (1989)

Fourteen derivatives of sparsomycin (1) were synthesized. Six of them were prepared following a novel synthetic route starting from the L-amino acid alanine. Some physicochemical properties, viz. lipophilicity and water solubility, of selected derivatives were measured. The biological activity was tested in vitro in cell-free protein synthesis inhibition assays, in bacterial and tumor cell growth inhibition assays, and in the L1210 leukemia in vivo model in mice. Also for selected drugs the acute toxicity in mice was determined. Ribosomes from both an eukaryotic and a prokaryotic organism were used in the protein synthesis inhibition systems. A linear correlation between the lipophilicity parameters measured was observed. Water solubility and drug toxicity in mice were found to be linearly correlated with lipophilicity. All the derivatives studied are more lipophilic than 1. The deshydroxysparsomycin analogues (30-33) showed an interesting phenomenon: increase in hydrophobicity was accompanied by a considerable increase in water solubility. We found that an increase in hydrophobicity of the drug as a result of replacing the SMe group of 1 with larger alkylthio groups causes an increase in the biological activity of the drug. However, not only the hydrophobicity but also shape and size of the substituent are important; in the homologous series 1-9-10-11-12, 21-22-23-24, and 30-31-32-33, highest protein synthesis inhibitory and in vitro cytostatic activity is found with compounds 11, 23, and 32, respectively, and in comparison with the highly active n-butyl compound 10, the isomeric tert-butyl compound 13 is rather inactive. Polar substituents replacing the SMe group, i.e. Cl in 17 and 35, also render the molecule inactive. Substituting the bivalent sulfur atom for a methylene group decreases the drug's activity. This effect can be compensated for by increasing the length of the alkylsulfinyl side chain. The agreement between the results derived from cell-free and "in vivo" tests is good. The assays using ribosomes of bacterial and eukaryotic organisms give similar results although the latter seem to be more sensitive to changes in hydrophobicity of the drug. Our results confirm the presence of a hydrophobic region at the peptidyl transferase center of the ribosome; the interaction of sparsomycin with this region is more pronounced in the eukaryotic particles. The sparsomycin analogues 11, 23, and 30 show the highest antitumor activity against L1210 leukemia in mice, their median T/C values are 386, 330, and 216%, respectively.(ABSTRACT TRUNCATED AT 400 WORDS)
Phase I trial of sargramostim in pediatric Crohn's disease (2010)

Sargramostim at both 4 and 6 mg/kg was well tolerated. PK analysis suggested dose proportionality unaffected by CS exposure. Remission and response data are encouraging, but further trials are needed to assess efficacy.
The Characterization and Properties of Cascade Realizable Switching Functions (1969)

This paper is a study of switching functions realizable by a single cascaded switching network composed of two-input, one-output elements where a distinct variable is applied to one input and the other receives the output of the previous element. A special type of Boolean formula called a standard cascade form is introduced with the property that all cascade realizable functions, and only these, can be written in this form. This characterization leads to a strong necessary condition on such functions: there is no consensus for any pair of its prime implicants which are, therefore, all core. It also leads to a new, efficient procedure for testing an arbitrary function f for cascade realizability. The test operates on the prime implicants of f, and yields a realization employing a particular complete set of cell types from which it is especially easy to derive any other realization using any other complete set.
Design and measurement of an active array antenna for an airborne X-Band SAR/MTI radar (2006)

A X-band electronically scanned active phased array antenna has been developed for an airborne SAR/MTI radar, with an European team from France, Germany, Italy, Netherlands and Spain. RF simulations and re-use or adaptation of available elements have made it possible to design and develop in a reduced time frame the different constitutive parts of the antenna assembly. In the integration process, the radiating unit has undergone a calibration process in a near field test range. Radiation patterns for the various modes, in the frequency band and within the angular field-of-view have been obtained through near-field to far-field transform, and the antenna assembly radiated power (EIRP) and quality factor (G/T) has been evaluated with a near-field procedures.
Purification and characterization of aldehyde dehydrogenase of Acetobacter aceti. (1981)

Acetate formation is catalyzed by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in acetic acid bacteria. They are typical membrane-bound enzymes and solubilized from the membranewith detergent. ADHfrom Acetobacter acetiX) and Gluconobacter suboxydans2) and ALDHfrom G. suboxydans3) have been purified to homogeneity and characterized enzymatically. They have been purified as an enzyme complex composed of dehydrogenase and c-type cytochrome. They catalyze a direct oxidation of individual substrates. Due to the instability of the solubilized enzyme, ALDHof A. aceti, a practical vinegar fermenter, has not been purified to homogenetiy. In this paper, the purification and characterization of the enzyme from A. aceti IFO 3284 are described and compared with the enzyme from G. suboxydans. Purified ADHand ALDHfrom two genera of acetic acid bacteria are also compared to each other. Cultivation of A. aceti, assays of enzyme activity and protein content, preparation of membranefraction and other analytical procedures were essentially the same as
Picture Gesture Authentication (2015)

Picture gesture authentication has been recently introduced as an alternative login experience to text-based password on touch-screen devices. In particular, the newly on market Microsoft Windows 8™ operating system adopts such an alternative authentication to complement its traditional text-based authentication. We present an empirical analysis of picture gesture authentication on more than 10,000 picture passwords collected from more than 800 subjects through online user studies. Based on the findings of our user studies, we propose a novel attack framework that is capable of cracking passwords on previously unseen pictures in a picture gesture authentication system. Our approach is based on the concept of selection function that models users’ thought processes in selecting picture passwords. Our evaluation results show the proposed approach could crack a considerable portion of picture passwords under different settings. Based on the empirical analysis and attack results, we comparatively evaluate picture gesture authentication using a set of criteria for a better understanding of its advantages and limitations.
Effects of 16O+6 ion irradiation on human sperm spontaneous chemiluminescence, motility, acrosome reaction and viability in vitro. (1999)

Effects of 16O+6 ion irradiation with different doses on human sperm spontaneous chemiluminescence (SCL), motility, acrosome reaction (AR) and viability were examined. Spermatozoa were irradiated with 0, 0.25, 0.5, 1, 2, 4, 8, 16, 32, or 64 Gy 16O+6 ion beam at the energy of 3.17 MeV/u. After irradiation, samples were analyzed by SCL measurement at 1, 2 and 3 h of incubation; motility was determined by the transmembrane migration method within 2 h of incubation; the percentage of AR and viability was evaluated by the triple-stain technique at 3.5 h of incubation. The results showed: sperm SCL was significantly increased with irradiation doses and the lowest effective dose was 0.5 Gy; compared with controls, the transmembrane migration ratio of spermatozoa progressively elevated with irradiation doses at 0.5, 1, and 2 Gy; the percentage of sperm AR markedly increased in 0.5-4 Gy irradiation and the optimal dose was 2 Gy, and then significant decreased with further increase of irradiation doses; the viability had no significant change within 0.25-8 Gy, but was progressively decreased at 16, 32 and 64 Gy. These data suggested that heavy ion at low doses increased motility and AR, whereas had deleterious effects at higher doses, which are associated with free radical reactions induced by heavy ion irradiation.
Shale Stabilization Principles (1985)

ABSTRACT Drilling troublesome shales successfully requires description and analytical tests of the shales, drilling fluid formulation, and field confirmation. This paper will point out strengths and weaknesses of our current approach and the need for better procedures.
Repression of Enzyme Synthesis of the Pyrimidine Pathway in <i>Salmonella typhimurium</i> (1973)

It has been reported by other workers that a uridine and probably also a cytidine nucleotide are required for maximal repression of aspartate transcarbamylase encoded by the gene pyrB in Salmonella typhimurium. We have identified the repressing metabolites for three more biosynthetic enzymes, namely, dihydroorotate dehydrogenase (encoded by pyrD), orotidine-5'-monophosphate pyrophosphorylase (encoded by pyrE), and orotidine-5'-monophosphate decarboxylase (encoded by pyrF), as well as examining the repression profiles of aspartate transcarbamylase in more detail. Using a specially constructed strain of S. typhimurium (JL1055) which lacks the enzymes for the interconversion of cytidine and uridine compounds, thus allowing the independent manipulation of endogenous cytidine and uridine nucleotides, we found that a cytidine compound is the primary effector of repression in all cases except for aspartate transcarbamylase where little repression is observed in excess cytidine. For aspartate transcarbamylase, we found that the primary repressing metabolite is a uridine compound.