gebhart/patrepeval huggingface dataset:
Glutamine-Binding Protein from<i>Escherichia</i><i>c</i><i>oli</i>Specifically Binds a Wheat Gliadin Peptide Allowing the Design of a New Porous Silicon-Based Optical Biosensor (2006)

In this work, the binding of the recombinant glutamine-binding protein (GlnBP) from Escherichia coli to gliadin peptides, toxic for celiac patients, was investigated by mass spectrometry experiments and optical techniques. Mass spectrometry experiments demonstrated that GlnBP binds the following amino acid sequence: XXQPQPQQQQQQQQQQQQL, present only into the toxic prolamines. The binding of GlnBP to gliadin suggested us to design a new optical biosensor based on nanostructured porous silicon (PSi) for the detection of trace amounts of gliadin in food. The GlnBP, which acts as a molecular probe for the gliadin, was covalently linked to the surface of the PSi wafer by a proper passivation process. The GlnBP-gliadin interaction was revealed as a shift in wavelength of the fringes in the reflectivity spectrum of the PSi layer. The GlnBP, covalently bonded to the PSi chip, selectively recognized the toxic peptide. Finally, the sensor response to the protein concentration was measured in the range 2.0-40.0 microg/L and the sensitivity of the sensor was determined.
Hyperledger-Based Secure Firmware Update Delivery for IoT Devices (2021)

The increase of relying on intelligent and connected devices in our home, company, and everyday life aspect leads to the rapid growth of the Internet of Things (IoT) technology. While some IoT devices communicate without the involvement of users, their functionalities must be protected against various attacks. This work proposes the delivery of a secure firmware update to IoT devices. Ensuring fast firmware updates should be implemented using a trusted network. In our proposal, we deployed blockchain to be our trusted network. The approach will be based on securely verifying the firmware version of the IoT device, validating the integrity of the firmware file, downloading the latest version of the firmware update. The primary objective is to mitigate the attacks targeting firmware updates of embedded devices by maintaining and guaranteeing the firmware is up-to-date and not altered in the IoT devices.
High Q, Temperature Stable ZnO-On-SILICON SAW RESONATORS (1980)

A monolithic SAW ZnO/Si02/Si resonator device is reported and several configurations for reflector structures are described. The tuo-port resonators are found to exhibit Q-values in the 2,000 to 10,000 range depending upon the use of m etallic or etched reflector arrays. Temperature compensation through the use of thick thermal oxide layers is also demonstrated. strips, as uell as grooves etched in the ZnO layer, to form efficient distributed r eflectors and to realize Lou values of i nsertion loss at the resonant frequency. In section I1 we discuss the results obtained with aluminum and chrome/gold ref lector strips, w hile s ection 111 consider chemically etched groove devices. The results o f temperature compensation experiments are discussed in section IV.
Nitrated lipids: A class of cell-signaling molecules (2004)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Photoswitchable Organic Nanofibers (2007)

A photoswitchable nanomaterial is presented, electrospun organic nanofibers based on 1',3'-dihydro-1',3',3'-trimethyl-6-nitrospiro [2H-1-benzopyran-2,2'-(2H)-indole]. The switching properties of the nanofibers were investigated by studying the evolution of absorbance with different UV exposure times, photoluminescence lifetime, cyclic photoisomerization, and reversible wettability. The unique potentialities of photoswitchable nanofibers for achieving enhanced control of surface wettability are shown.
Molecular cloning and characterization of a proline iminopeptidase gene from <i>Neisseria gonorrhoeae</i> (1993)

Proline iminopeptidase (Pip) is a hydrolase elaborated by virtually all strains of Neisseria gonorrhoeae that selectively removes N-terminal proline residues from peptides. Escherichia coli clones expressing the gonococcal gene coding for Pip were identified in a genomic cosmid library using a synthetic colorimetric substrate. Nucleotide sequence determination and analyses of polypeptides detected by coupled in vitro transcription/translation reactions revealed that Pip is a 311-amino-acid polypeptide with a M(r) of 35 kDa and a pI of 5.4. Southern hybridization showed that the pip gene is present in a single copy on the chromosome of N. gonorrhoeae strain MS11 which maps immediately upstream of the previously identified opaA locus. The transcriptional start site of pip in E. coli, determined by primer extension analysis, was characteristic of an NtrA or sigma-54-dependent promotor. Complementation of an E. coli mutant deficient in both proline biosynthesis and dipeptide uptake confirmed that Pip is capable of releasing biologically active proline from peptides. Pip expression was found to be non-essential for in vitro growth of N. gonorrhoeae, based on the viability of a Pip- gonococcal mutant.
Automated identification of medical concepts and assertions in medical text. (2010)

This paper describes a machine learning, text processing approach that allows the extraction of key medical information from unstructured text in Electronic Medical Records. The approach utilizes a novel text representation that shares the simplicity of the widely used bag-of-words representation, but can also represent some form of semantic information in the text. The large dimensionality of this type of learning models is controlled by the use of a ℓ(1) regularization to favor parsimonious models. Experimental results demonstrate the accuracy of the approach in extracting medical assertions that can be associated to polarity and relevance detection.
Regulation of Multidrug Resistance in Cancer Cells by Hyaluronan (2003)

Multidrug resistance in cancer cells is often due to ATP-dependent efflux pumps, but is also linked to alterations in cell survival and apoptotic signaling pathways. We have found previously that perturbation of hyaluronan-tumor cell interaction by treatment with hyaluronan oligosaccharides suppresses the phosphoinositide 3-kinase/Akt cell survival signaling pathway in cancer cells and reduces tumor growth in vivo. Here we find that these oligomers suppress both the MAP kinase and phosphoinositide 3-kinase pathways in multidrug resistant tumor cells and sensitize these cells to a variety of chemotherapeutic drugs. On the other hand, increased hyaluronan production induces resistance in drug-sensitive tumor cells. Likewise, increased expression of emmprin, which is a glycoprotein that is present on the surface of most malignant cancer cells and that stimulates hyaluronan production, also induces increased resistance. Thus, perturbation of hyaluronan signaling may provide a dual therapeutic role, since it has intrinsic suppressive effects on tumor growth as well as sensitizing cancer cells to chemotherapeutic agents.
Synthesis of carbon nanotubes by combustion of a paraffin wax candle (2007)

A method for the synthesis of multi-walled carbon nanotubes (MWCNTs) using paraffin wax candles is reported. The MWCNTs were grown on a cobalt-coated silicon wafer with a combustion rate of 80 s at a flame temperature of 700°C. The MWCNTs are 15–20 nm in diameter and ∼1–3 µm in length. Raman spectroscopy revealed that the IG/ID ratio is 0.88. The growth of the MWCNTs was studied using different combustion times. The amount of MWCNTs decreased for experiments longer than 80 s, presumably because the MWCNTs were burned off with a long stay in the flame.
Kinematic localization for world model calibration in off-line robot programming using Clifford algebra (2002)

The calibration of spatial relationships among CAD models of objects used in offline robot programming is discussed. An approach based on a Clifford algebra is used, and simple algorithms for this kinematic localization problem are developed. The position and orientation of each object in a workcell are represented by multivectors of different ranks and the localization problem is converted into that of solving a set of multivector equations. Given locations of points in two frames, an averaging process which yields the best orientation as the root of four linear equations and the best position as a linear combination of the best rotation and the centroids of two point systems is developed. If normal vectors are also sensed, the Clifford algebra representation facilitates definition of a measure of orientation error compatible with the position error.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The effect of sodium nitroprusside on psychotic symptoms and spatial working memory in patients with schizophrenia: a randomized, double-blind, placebo-controlled trial (2016)

Although this study was negative, it is possible that the beneficial effects of SNP may occur in patients with a shorter history of illness, or with more acute exacerbation of symptoms.
Social media-based three-screen TV service (2011)

This paper presents a practical application of interactive TV in baseball watching. It has two features. First of all, it employs social media to generate semantic metadata of the media stream that reflect the interest of the public. The metadata are extracted by our proposed bursty feature extraction algorithm, and it provides immediate but rich summaries of live TV contents. Second, utilizing them, three-screen TV service was proposed to provide a new interactive TV watching environment. In the environment, metadata make the system available on interest-based information providing and suitable intelligent interface. We implemented a prototype system in a baseball watching environment at home or public viewing zone.
Anaerobic Digester Optimization using Factorial Design Approach (2009)

Anaerobic Digester Optimization using Factorial Design ApproachThe object of this study was to optimize operating conditions of anaerobic digesters using factorial design approach. Three operating parameters were of concern; (1) mixing, (2) mean cell residence time (MCRT) and (3) solids loadings. Mixing intensity was applied in two modes; low mixing and high mixing. MCRTs tested in the study were 15 and 25 days. The feed to the bench-scale digesters,...Author(s)Cheol ParkAlbana BegaJoseph FarrellJonathan KeaneyWilliam E. ToffeyJason A. HuntPaul M. KohlWilliam R. McKeonJohn WillisMetin DuranSourceProceedings of the Water Environment FederationSubjectSession 5 - Anaerobic Digestion 2Document typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2009ISSN1938-6478SICI1938-6478(20090101)2009:3L.350;1-DOI10.2175/193864709793846015Volume / Issue2009 / 3Content sourceResiduals and Biosolids ConferenceFirst / last page(s)350 - 361Copyright2009Word count279Subject keywordsAnaerobic digestionfactorial designmixingsolids loadingMCRT
Light Absorption by Carbonaceous Particles: An Investigative Review (2005)

The optical properties of the light-absorbing, carbonaceous substance often called "soot," "black carbon," or "carbon black" have been the subject of some debate. These properties are necessary to model how aerosols affect climate, and our review is targeted specifically for that application. We recommend the term light-absorbing carbon to avoid conflict with operationally based definitions. Absorptive properties depend on molecular form, particularly the size of sp 2-bonded clusters. Freshly-generated particles should be represented as aggregates, and their absorption is like that of particles small relative to the wavelength. Previous compendia have yielded a wide range of values for both refractive indices and absorption cross section. The absorptive properties of light-absorbing carbon are not as variable as is commonly believed. Our tabulation suggests a mass-normalized absorption cross section of 7.5 ± 1.2 m2/g at 550 nm for uncoated particles. We recommend a narrow range of refractive indices for strongly-absorbing carbon particles, of which the highest is 1.95–0.79i. Our refractive indices are consistent with most measurements reported in the literature, and values used in present-day climate modeling are in error. Realistic refractive indices underpredict measured absorption by about 30% when used with common theories for spherical particles or aggregates. Field programs since about 1970 have measured quantities relevant to light absorption, but have only recently made enough measurements to isolate the light-absorbing carbonaceous component and determine its absorptive properties.
Construction of a recombinant intergenus multidomain chimeric protein for simultaneous expression of haemolysin BL of Bacillus cereus, listeriolysin O of Listeria monocytogenes and enterotoxin B of Staphylococcus aureus (2009)

Haemolysin BL (HBL) of Bacillus cereus, listeriolysin O (LLO) of Listeria monocytogenes and enterotoxin B (SEB) of Staphylococcus aureus are among the major toxin components contributing to the pathogenicity of these organisms in foodborne illnesses. In this study, an intergenus non-toxic multidomain fusion protein (r-HLE) was generated with specificity for HBL, LLO and SEB. The fusion gene (r-hle) comprising the conserved regions of hblD and the hly and entB genes was codon-optimized for expression in Escherichia coli and encoded a 50 kDa recombinant multidomain chimeric protein (r-HLE). Hyperimmune antiserum raised against r-HLE specifically reacted with the L1 (38 kDa) component of the HBL complex of B. cereus, LLO (58 kDa) of L. monocytogenes and SEB (28 kDa) of S. aureus during Western blot analysis when tested on standard strains. During testing on isolates, the antiserum again identified the appropriate toxin molecules and was highly specific to the relevant bacterial species. The antigenicity of the SEB component of the r-HLE protein was also confirmed using a commercially available TECRA kit. The described procedure of creating a single antigenic molecule carrying components of three different toxins whilst still retaining the original antigenic determinants of individual toxins will be highly advantageous in the development of rapid, reliable and cost-effective immunoassays.
Ion Exchange. (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIon Exchange.Robert Kunin and George BodamerCite this: Ind. Eng. Chem. 1959, 51, 3, 373–377Publication Date (Print):March 1, 1959Publication History Published online1 May 2002Published inissue 1 March 1959https://pubs.acs.org/doi/10.1021/ie51395a009https://doi.org/10.1021/ie51395a009research-articleACS PublicationsRequest reuse permissionsArticle Views68Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Carbon nanocage structures formed by one-dimensional self-organization of gold nanoparticles (1999)

Carbon nanocapsules and nanotubes have been formed by one-dimensional self-organization of gold nanoparticles, caused by the adhesive force at the step edge of amorphous carbon thin films; the present result is expected to be a promising fabrication technique for self-assembling nanowires and cluster-protected quantum dots at scales beyond the limits of current photolithography.
Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin (2007)

Sclerostin, the protein product of the Sost gene, is a potent inhibitor of bone formation. Among bone cells, sclerostin is found nearly exclusively in the osteocytes, the cell type that historically has been implicated in sensing and initiating mechanical signaling. The recent discovery of the antagonistic effects of sclerostin on Lrp5 receptor signaling, a crucial mediator of skeletal mechanotransduction, provides a potential mechanism for the osteocytes to control mechanotransduction, by adjusting their sclerostin (Wnt inhibitory) signal output to modulate Wnt signaling in the effector cell population. We investigated the mechanoregulation of Sost and sclerostin under enhanced (ulnar loading) and reduced (hindlimb unloading) loading conditions. Sost transcripts and sclerostin protein levels were dramatically reduced by ulnar loading. Portions of the ulnar cortex receiving a greater strain stimulus were associated with a greater reduction in Sost staining intensity and sclerostin-positive osteocytes (revealed via in situ hybridization and immunohistochemistry, respectively) than were lower strain portions of the tissue. Hindlimb unloading yielded a significant increase in Sost expression in the tibia. Modulation of sclerostin levels appears to be a finely tuned mechanism by which osteocytes coordinate regional and local osteogenesis in response to increased mechanical stimulation, perhaps via releasing the local inhibition of Wnt/Lrp5 signaling.
Graphitic carbon anode temperature excursions reflect crystallographic phase transitions in lithium-ion cells (2015)

Surface temperature measurement of lithium-ion cells provides a limited view of internal physical processes during charging. Using a recently developed non-invasive battery internal temperature sensor, we now demonstrate that anode temperature reflects physically-based dynamics at the anode that were previously obscured by cell-surface measurements. First, using automated segmentation with a maximum-likelihood piecewise-linear statistical model, we show that features in the anode temperature reproducibly coincide with phase transitions into Stages IVd, IV and I of graphitic carbon lithiation at various charging rates. Second, we show that anode temperature peaks around 61% state of charge, intermediate between Stages II and I of the lithiated graphitic carbon. Third, we demonstrate a sharp and sustained increase in anode temperature at variable state of charge above 85%. These findings open the possibility for improved state-of-charge estimation and adaptive charging profiles that safely reduce charging time.
Procedure semantics and language definition (1980)

Semantics for procedures and their calls is proposed which describes two cases often considered to be outside contemporary programming languages: distributed computing and procedure calls that contain aliases. It is argued that this semantics should be used as the basis of programming language definition because it is simple, intuitive and unifies these seemingly different cases. To support this argument, a verification rule for procedure calls with aliases is given which is no more complicated than those found in the literature. This verification rule is possible only because it is based on the proposed semantics.
The Effects of Personal Well-Being on Adaptation to Relocation Effect Among Elders Living in the Hermitage (1996)

This study investigates what constitutes an optimal environment for facilitating adaptation to relocation effect, a phenomenon that tends to threaten perceived well-being of people following a change of their address, including intrahospital relocations such as those from intensive to acute to rehabilitative care. Data were derived during 18 months of research conducted among the population of 154 elders who chose to reside in formal retirement at "The Hermitage," and whose daily needs were met by a staff of 40 people (1:4). These residents were at least 65 years old, able to live either independently (mentally and physically self-reliant) or with personal care (assistance with daily activities), and, because The Hermitage is not vendor-contracted, financially solvent. A sample population of 37 women and 4 men (average age, 85; age range, 76 to 95) was gathered through random encounters in the home, serendipitously representing the percentage of women to men in its total population. Methodology was a qualitative-quantitative mix including participant observation, key-informant interviews, the Cantril Self-anchoring Scale, and the Body Image Scale. Research findings show 1) all of these old people experienced some degree of relocation effect initiated by challenges of relocation; 2) the staff was primary in ameliorating relocation effect; and 3) relocation effect resolved as these elders experienced enhanced well-being, leading to successful adaptation.
Vehicle Type Measurement Using a Laser Distance Sensor with High Pulse Repetition and Accuracy (2010)

To ensure traffic security and avoid traffic congestion, accommodation lane is set. A vehicle type measurement device is used to capture the violation drivers. The vehicle type measurement device uses a laser distance sensor with 1.2 KHz pulse repetition and 20 mm accuracy per pulse. The experiment shows that this laser distance sensor can obtain the vehicle profiles to distinguish bus, camion, trailer, sedan and taxi. The chip TDC-GP2 chip is used in the sensor to realize the performance.
The Effect of Participation on Health Care Patterns in a disease Aged Physical Activities (2004)

The purpose of this study was to analyze. The effect of participation physical activities on health care patterns in the aged. The subject of the study was selected by multi-stage stratified cluster random sampling among the aged center and aged club to participate program whose age were 65 and over year old among inhabitant the Kwangju metropolitan area. The data were collected through a questionnaire adapted from Payne and Hahn's(1986) 'Understanding Your Health-A personal profile; Evaluating Your Health'. The pilot test was executed after the questionnaire was translated into Korean.
Hepatitis C virus genotypes in Saudi Arabia: a future prediction and laboratory profile (2017)

Although HCV genotype 4 shows an overall high prevalence in this study, a clear decline in the rate of this genotype was also demonstrated in particular among the younger age group who displayed increasing trends toward the global trend of genotype 1, rather than genotype 4. This finding would be of clinical interest in relation to future planning of the therapy for HCV infected patient.
Spikernels: Embedding Spiking Neurons in Inner-Product Spaces (2002)

Inner-product operators, often referred to as kernels in statistical learning, define a mapping from some input space into a feature space. The focus of this paper is the construction of biologically-motivated kernels for cortical activities. The kernels we derive, termed Spikernels, map spike count sequences into an abstract vector space in which we can perform various prediction tasks. We discuss in detail the derivation of Spikernels and describe an efficient algorithm for computing its value on any two sequences of neural population spike counts. We demonstrate the merits of our modeling approach using various kernels for the task of predicting hand movement velocities from cortical recordings. In all of our experiments all the kernels we tested outperform the standard scalar product used in regression with the Spikernel consistently achieving the best performance.