gebhart/patrepeval huggingface dataset:
Unencapsulated Air-stable Organic Field Effect Transistor by All Solution Processes for Low Power Vapor Sensing (2016)

With its excellent mechanical flexibility, low-cost and low-temperature processing, the solution processed organic field-effect transistor (OFET) is a promising platform technology for developing ubiquitous sensor applications in digital health, environment monitoring and Internet of Things. However, a contradiction between achieving low voltage operation and having stable performance severely hinder the technology to become commercially viable. This work shows that, by reducing the sub-gap density of states (DOS) at the channel for low operation voltage and using a proper low-k non-polar polymer dielectric layer, such an issue can be addressed. Stable electrical properties after either being placed for weeks or continuously prolonged bias stressing for hours in ambient air are achieved for all solution processed unencapsulated OFETs with the channel being exposed to the ambient air for analyte detection. The fabricated device presents a steep subthreshold swing less than 100 mV/decade, and an ON/OFF ratio of 10(6) at a voltage swing of 3 V. The low voltage and stable operation allows the sensor made of the OFET to be incorporated into a battery-powered electronic system for continuously reliable sensing of ammonia vapor in ambient air with very small power consumption of about 50 nW.
Tissue plasminogen activator: Comparison of dose and route of administration in a rabbit model of thromboembolic stroke (1993)

The thrombolytic activity of tissue plasminogen activator was evaluated in a rabbit model of thromboembolic stroke using both various concentrations (3, 5, and 10 mg/kg; 20% bolus with the remaining 80% given over 30 min.) and routes of administration (intravenous versus regional intra-arterial). An autologous tin-tagged clot was embolized to the brain via the carotid artery. Tissue plasminogen activator was then given at the doses and routes noted (n = 3 in all groups). Thrombolytic activity was followed by serial x-rays of the tin-laden clot over a four-hour period. The brains were then removed and subjected to gross inspection. Only the intravenous dose of 5 mg/kg tissue plasminogen activator produced greater than 50% clot lysis in all animals. Doses of t-PA higher (10 mg/kg) or lower (3 mg/kg) than this were less effective in producing thrombolysis, demonstrating greater than 50% clot lysis in only one animal of each group. We conclude that in this model of thromboembolic stroke the intravenous administration of tissue plasminogen activator is more effective than intra-arterial, and that the optimal dose is in the range of 5 mg/kg.
Note on Modified Extraction Procedure for the Colorimetric Determination of Diethylstilbestrol in Mixed Feeds (1966)

Journal Article Note on Modified Extraction Procedure for the Colorimetric Determination of Diethylstilbestrol in Mixed Feeds Get access Fred H Hoskins Fred H Hoskins Department of Food Science and Technology, Louisiana State University, Baton Rouge, La. 70803 Search for other works by this author on: Oxford Academic Google Scholar Journal of Association of Official Analytical Chemists, Volume 49, Issue 3, 1 June 1966, Page 497, https://doi.org/10.1093/jaoac/49.3.497 Published: 01 February 2020
Porous silicon microparticles as an embolic agent for the treatment of hepatocellular carcinoma (2011)

Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide, accounting for over 600,000 deaths per year. The most common treatment strategy for intermediate and advanced stage unresectable HCC is transarterial chemoembolization (TACE), which involves the local administration of a chemotherapeutic drug combined with arterial occlusion resulting in ischemic tumor necrosis. However, TACE suffers from inadvertent exposure of noncancerous liver parenchyma to embolic agents resulting in liver injury. In some cases, over-embolization has lead to infection, necrosis of unaffected liver tissue, and even liver failure which suggests the need for a biocompatible, multifunctional embolic material which can deliver anticancer drugs with high target specificity. Our laboratory has recently developed a method to fabricate porous silicon (pSi) microparticles with defined physicochemical properties based on photolithography and anodic etching. These microparticles function as multistage drug delivery systems that can circumvent the biobarriers present in the systemic circulation enabling site-specific localization and release of chemotherapy and imaging agents. The versatility of the fabrication process enables the realization of microparticles ranging in size from 600nm to 116[mu]m in diameter with varying shapes, including discoidal, cylindrical and hemispherical, and varying porosity with pore sizes ranging from 6nm to greater than 50nm in diameter. Nanoparticles, such as quantum dots, siRNA-loaded nanoliposomes, gadolinium-based contrast agents, gold and iron oxide nanoparticles, are loaded in pSi microparticles by tailoring their pore sizes and surface chemistries. This thesis presents preliminary results on the applicability of biocompatible, engineered pSi microparticles as an embolic agent for HCC chemoembolization therapy. Hemispherical microparticles with 116[mu]m diameter were successfully fabricated and suspended in phosphate buffered saline (PBS). A microvascular construct was rapid prototyped in polydimethylsiloxane (PDMS) as an in vitro experimental platform to study the embolization behavior of pSi microparticles. Oxidized pSi microparticles were introduced into the microfluidic device at an appropriate flow rate and time-lapse images were taken showing the formation of occlusions at the bifurcation within minutes of administration. Furthermore, penetration through the bifurcation was completely hindered suggesting that pSi microparticles can potentially be used as a biocompatible, multifunctional chemoembolization agent. Although these results are promising, further investigations are warranted.
Clinical and mutational spectrum of limb-girdle muscular dystrophy type 2I in 11 French patients (2009)

This study reveals inter- and intrafamilial phenotypic variability in LGMD2I, with a preponderance of myocardiopathy and restrictive respiratory insufficiency. It also demonstrates central nervous involvement, probably associated with changes in alpha-dystroglycan expression in the brain.
Standby power optimization via transistor sizing and dual threshold voltage assignment (2002)

This paper presents a novel enumerative approach, with provable and efficient pruning techniques, for dual threshold voltage (Vt) assignment at the transistor level. Since the use of low Vt may entail a substantial increase in leakage power, we formulate the problem as one of combined optimization for leakage-delay tradeoffs under Vt optimization and sizing. Based on an analysis of the effects of these two transforms on the delay and leakage, we justify a two-step procedure for performing this optimization. Results are presented on the ISCAS85 benchmark suite favorably comparing our approach with an existing sensitivity-based optimizer.
Exploring Extension Involvement in Farm to School Program Activities (2014)

The study reported here examined Extension professionals' involvement in farm-to-school program activities. Results of an online survey distributed to eight state Extension systems indicate that on average, Extension professionals are involved with one farm to school program activity, with most supporting school or community garden programs. Results also indicate that Extension professionals are interested in being involved with an average of four farm to school program activities. Results demonstrate that each Extension program area is currently involved and is interested in supporting farm to school through a variety of different activities.
'Shoe Leather Therapy' Is Gaining on TB (1996)

THROUGHOUT the dimly lit hallways of a Newark, NJ, housing project, a musty odor mingles with the smell of urine and cooking food. Darryl Sabu Kilgore takes it in stride as he gently raps on the door of Belinda Warren's one-room apartment. Warren is a young woman, but she moves slowly. She manages a faint smile for Kilgore, who's a regular visitor. So regular, in fact, that he follows Warren's frequent moves—four in the last 6 months alone. If he lost track of her, Warren might not take her tuberculosis (TB) medication. The result could be life-threatening multidrug-resistant TB for Warren and the risk of an outbreak in the building where she lives. "We're aggressive in our approach to getting people cured," says Kilgore, a public health representative at the University of Medicine and Dentistry of New Jersey—New Jersey Medical School's National Tuberculosis Center in Newark. <h3>Getting Results</h3> Kilgore, like
Salen−Manganese Complexes as Catalytic Scavengers of Hydrogen Peroxide and Cytoprotective Agents:  Structure−Activity Relationship Studies (2002)

Synthetic catalytic scavengers of reactive oxygen species (ROS) may have broad clinical applicability. In previous papers, two salen-manganese complexes, EUK-8 and EUK-134, had superoxide dismutase (SOD) and catalase activities and prevented ROS-associated tissue injury. This study describes two series of salen-manganese complexes, comparing catalytic ROS scavenging properties and cytoprotective activities. The compounds vary widely in ability to scavenge hydrogen peroxide, with this activity most influenced by salen ring alkoxy substitution and aromatic bridge modifications. In contrast, all compounds show comparable SOD activities. The most active alkoxy-substituted catalase mimetics protected cultured cells from hydrogen peroxide, and a subset of these were also neuroprotective in a rodent stroke model. Thus, structural modification of the prototype EUK-8 yields compounds with enhanced catalase activity and, in turn, biological effectiveness. This supports the concept that salen-manganese complexes represent a class of SOD and, in particular, catalase mimetics potentially useful against ROS-associated diseases.
Rates and equilibria of alkali metal and silver ion complex formation with monensin in ethanol (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRates and equilibria of alkali metal and silver ion complex formation with monensin in ethanolB. G. Cox, N. Van Truong, J. Rzeszotarska, and H. SchneiderCite this: J. Am. Chem. Soc. 1984, 106, 20, 5965–5969Publication Date (Print):October 1, 1984Publication History Published online1 May 2002Published inissue 1 October 1984https://pubs.acs.org/doi/10.1021/ja00332a035https://doi.org/10.1021/ja00332a035research-articleACS PublicationsRequest reuse permissionsArticle Views140Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A High-Speed Logic System Using Magnetic Elements and Connecting Wire Only (1959)

By introducing geometric variation in the basic magnetic core toroidal structure, new logic design freedom is achieved and effective decoupling is obtained between different windings linking the same element. By proper interconnection such elements may be used to provide unilateral information-flow properties without the use of explicit unilateral devices such as diodes. A practical system to accomplish this is outlined in this paper. The resulting circuits are relatively fast and inexpensive. Magnetic elements and connecting wires only are required. In particular, single-turn windings may be used in the coupling loops. Furthermore, inherent nondestructive read properties allow a great deal of logic facility. Simple shift register structures and logic elements and circuits are described.
Simulation Analysis of Experimental Design Strategies for Screening Random Compounds as Potential New Drugs and Agrochemicals (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimulation Analysis of Experimental Design Strategies for Screening Random Compounds as Potential New Drugs and AgrochemicalsRobin TaylorCite this: J. Chem. Inf. Comput. Sci. 1995, 35, 1, 59–67Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://doi.org/10.1021/ci00023a009RIGHTS & PERMISSIONSArticle Views286Altmetric-Citations107LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1008 KB) Get e-Alerts
Dual-channel near-infrared/visible imaging systems (1998)

Two imaging systems for 1 meter telescope with f/ratios of f/10 and f/16 capable of simultaneous operation in any one of the U, B, V or R passbands together with any one of the J, H or K passbands are described. The visible bands are separated from the IR bands by a dichroic beam-splitter. Identical fields are imaged on a 2048 by 2048 CCD with 15 micron pixels, and an InSb 1024 by 1024 array with 27 micron pixels at a scale of 0.3 arc-seconds per pixel. The system uses reflective optics prior to the dichroic followed by refractive optics to produce the final f/ratios. The astigmatism introduce into the IR transmitted beam by the dichroic substrate is corrected using a cylindrical mirror. An additional prismatic correction necessitated by the dispersion in the beam splitter is also addressed.
Host range restrictions of oncogenes: myc genes transform avian but not mammalian cells and mht/raf genes transform mammalian but not avian cells. (1996)

The host range of retroviral oncogenes is naturally limited by the host range of the retroviral vector. The question of whether the transforming host range of retroviral oncogenes is also restricted by the host species has not been directly addressed. Here we have tested in avian and murine host species the transforming host range of two retroviral onc genes, myc of avian carcinoma viruses MH2 and MC29 and mht/raf of avian carcinoma virus MH2 and murine sarcoma virus MSV 3611. Virus vector-mediated host restriction was bypassed by recombining viral oncogenes with retroviral vectors that can readily infect the host to be tested. It was found that, despite high expression, transforming function of retroviral myc genes is restricted to avian cells, and that of retroviral mht/raf genes is restricted to murine cells. Since retroviral oncogenes encode the same proteins as certain cellular genes, termed protooncogenes, our data must also be relevant to the oncogene hypothesis of cancer. According to this hypothesis, cancer is caused by mutation of protooncogenes. Because protooncogenes are conserved in evolution and are presumed to have conserved functions, the oncogene hypothesis assumes no host range restriction of transforming function. For example, mutated human proto-myc is postulated to cause Burkitt lymphoma, because avian retroviruses with myc genes cause cancer in birds. But there is no evidence that known mutated protooncogenes can transform human cells. The findings reported here indicate that host range restriction appears to be one of the reasons (in addition to insufficient transcriptional activation) why known, mutated protooncogenes lack transforming function in human cells.
PA7300LC integrates cache for cost/performance (2002)

HP continues its development of low cost, high performance processors with an evolution of the PA7100LC which includes 128 kB of on-chip primary cache. It implements the full PA-RISC1.1 functionality including the little-endian, uncacheable memory, and multimedia extensions of the PA7100LC. The PA7300LC connects directly to an optional second level cache of 256 kB to 64 MB using plug-in cards. It also adds the ability to accelerate I/O stores to certain memory locations for greatly improved graphics performance. The cache system consists of on-chip, 2-way, separate instruction and data caches of 64 kB total each, plus the off-chip second level cache. Memory consists of 8 MB to 3.75 GB of standard DRAMs or SIMMs connecting directly to the processor chip, using either a 72 bit or 144 bit data path. The chip is fabricated in 0.5 micron, 4-level metal CMOS and is designed to run at frequencies up to 160 MHz. The PA7300LC exceeds performance levels of previous generation high-end workstations while lowering overall system cost and power consumption.
Supercritical Fluid Extraction (SFE)-An Overview (2012)

Among the different extraction techniques used at analytical and preparative scale, supercritical fluid extraction (SFE) is one of the most used separation technique, which mostly depends on critical temperature and pressure of supercritical fluid. This review covers the most recent developments of SFE indifferent fields (SFE applications), such as food science, natural products, by-product recovery, pharmaceutical and environmental sciences, during the period 2007–2009. The revision is focused on the most recent advances and applications in the different areas; among them, it is remarkable the strong impact of SFE to extract high value compounds from food and various natural products but also its increasing importance in areas such as heavy metals recovery, enantiomeric resolution or drug delivery systems
Raman scattering study on anatase TiO<sub>2</sub>nanocrystals (2000)

Titanium dioxide (TiO 2 ) nanocrystals are prepared by a hydrolysis process of tetrabutyl titanate. Nanocrystal samples with various sizes of 6.8-27.9 nm are obtained after annealing from 100 to 650 °C. The crystal structures and the average particle sizes are examined using x-ray diffraction. Raman scattering was employed to investigate the evolution of the anatase phase in the nanocrystals during annealing. Phonon confinement and non-stoichiometry effects are responsible for the blueshift and broadening of the lowest-frequency E g Raman mode. The influence of interfacial vibrations on the Raman linewidth is also discussed.
Development of preventive maintenance system for highly reliable gas insulated switchgear (1991)

The concept of gas-insulated switchgear (GIS) preventive maintenance system construction is presented along with application examples and new sensing technologies. High-sensitivity partial discharge, abnormal current conduction, and methods of detecting very-small-particles are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Molecular Typing of<i>Mycobacterium tuberculosis</i>by Using Nine Novel Variable-Number Tandem Repeats across the Beijing Family and Low-Copy-Number IS<i>6110</i>Isolates (2003)

Molecular epidemiological tools for genotyping clinical isolates of Mycobacterium tuberculosis have been developed and used to help track and contain transmission of tuberculosis. We identified 87 short sequence repeat loci within the genome of the M. tuberculosis H37Rv strain. Nine tandem repeats were found to be variable (variable-number tandem repeats [VNTRs]) in a set of 91 isolates. Fifty-seven of the isolates had only four IS6110 bands. The other 34 isolates were members of the Beijing strain family. The number of alleles of each these nine VNTRs was determined by examining each isolate. Six of the loci (Mtb-v1, -v4, -v10, -v15, -v18, and -v20) were able to differentiate the Beijing spoligotype identical isolates into seven distinct genotypes. Five of the loci (Mtb-v3, -v5, -v6, -v10, and -v15) were informative in discriminating the four-band IS6110 restriction fragment length polymorphism isolates from each other. The Nei's diversity values of each marker ranged from 0.02 to 0.59, with the number of alleles ranging from two to eight across the entire strain set. These nine loci provide a useful, discriminatory extension of VNTR typing methods for application to molecular epidemiologic studies of M. tuberculosis.
Accessing hyperdocuments through interactive dynamic maps (1994)

We propose a new navigation paradigm based on a spatial metaphor to help users access and navigate within large sets of documents. This metaphor is implemented by a computer artifact called an Interactive Dynamic Map (IDM). An IDM plays a role similar to the role of a real map with respect to physical space. Two types of IDMs are computed from the documents: Topic IDMs represent the semantic contents of a set of documents while Document IDMs visualize a subset of documents such as those resulting from a query. IDMs can be used for navigating, browsing, and querying. They can be made active, they can be customized and they can be shared among users. The article presents the SHADOCS document retrieval system and describes the role, use and generation of IDMs in SHADOCS.
Design tradeoffs for data deduplication performance in backup workloads (2015)

Data deduplication has become a standard component in modern backup systems. In order to understand the fundamental tradeoffs in each of its design choices (such as prefetching and sampling), we disassemble data deduplication into a large N-dimensional parameter space. Each point in the space is of various parameter settings, and performs a tradeoff among backup and restore performance, memory footprint, and storage cost. Existing and potential solutions can be considered as specific points in the space. Then, we propose a general-purpose framework to evaluate various deduplication solutions in the space. Given that no single solution is perfect in all metrics, our goal is to find some reasonable solutions that have sustained backup performance and perform a suitable tradeoff between deduplication ratio, memory footprints, and restore performance. Our findings from extensive experiments using real-world workloads provide a detailed guide to make efficient design decisions according to the desired tradeoff.