gebhart/patrepeval huggingface dataset:
Twisted GFSR generators (1992)

The generalized feed back shift register (GFSR) algorithm suggested by Lewis and Payne is a widely used pseudorandom number generator, but has the following serious drawbacks: (1) an initialization scheme to assure higher order equidistribution is involved and is time consuming; (2) each bit of the generated words constitutes an m -sequence based on a primitive trinomials, which shows poor randomness with respect to weight distribution; (3) a large working area is necessary; (4) the period of sequence is far shorter than the theoretical upper bound. This paper presents the twisted GFSR (TGFSR) algorithm, a slightly but essentially modified version of the GFSR, which solves all the above problems without loss of merit. Some practical TGFSR generators were implemented and passed strict empirical tests. These new generators are most suitable for simulation of a large distributive system, which requires a number of mutually independent pseudorandom number generators with compact size.
24-GHz Integrated Radio and Radar System Capable of Time-Agile Wireless Communication and Sensing (2012)

This paper presents an integrated radio and radar system using a single transceiver platform towards millimeter-wave applications. In the proposed system, wireless communication and sensing functions are fully integrated and sequentially arranged in the time domain so that they can operate independently (functional reconfiguration) and also jointly (functional fusion). For this proof-of-principle study, a system prototype is developed in the 24-GHz ISM band using the emerging substrate integrated waveguide (SIW) technology, which has been demonstrated as an attractive low-cost and high-efficiency development scheme for microwave and millimeter-wave systems. Experimental results show a very promising system performance. In addition to high-precision range detection with its radar mode, the present system has proved to have a great capability of wireless radio communication at a data rate of up to 50 Mbps for both binary-phase-shift-keying (BPSK) and quadrature-phase-shift-keying (QPSK) signals.
Genetics of spoken language disorders. (1998)

If language is the result of specialized structures in the brain and if these language-specific structures are genetically encoded, one would expect to find evidence of the heritability of language. In this article I review the results of family aggregation, pedigree, sex ratio, commingling, and segregation studies of spoken language disorders. The results of these studies provide evidence that, although spoken language disorders are genetically and behaviorally heterogeneous, genetic factors may play a substantial role in many cases of developmental spoken language disorders.
A Necessidade de Terminologia Especializada de Administração Pública em Português e Espanhol (1953)

O Professor Benedicto Silva, autor do presente artigo, além de suas inúmeras contribuições de relevante mérito para o aperfeiçoamento administrativo do Brasil, tem uma notável folha do serviços prestados à nossa cultura técnica. Entre suas grandes iniciativas em prol do movimento reformador de nossa burocracia, vale resultar as iniciativas de criação da “Revista do Serviço Público”, em 1937, e dos Cursos de Aperfeiçoamento do D . A . S. P ., em 1941.
Renal Failure, Acute (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Application of Numeric Protective Relay Circuit Breaker Duty Monitoring (2005)

Most numeric or digital protective overcurrent systems on the market today state that they have some ability to provide an indication, based on parameters that are input by the user, that circuit breaker maintenance may be needed soon. This paper will look at variables in a protective relay's ability to provide the user with an indication of its associated circuit breaker's health based upon the amount of current the circuit breaker has interrupted and the associated energy dissipation in the circuit breaker contact surfaces. The variables in an arc energy formula will be examined and the complications related to estimating the associated wear or circuit breaker duty level from interrupted current will be reviewed. Practical examples will include calculations of circuit breaker wear at load currents and for full rated fault interruptions.
Polarization microscopy with the LC-PolScope (2003)

Author Posting. © The Author(s), 2003. This is the author's version of the work. It is posted here by permission of Cold Spring Harbor Laboratory Press for personal use, not for redistribution. The definitive version was published in Live Cell Imaging : A Laboratory Manual, edited by R. D. Goldman and D. L. Spector, :205-237. Cold Spring Harbor Laboratory Press, 2005. ISBN: 9780879696825.
A dynamic flow-weighted pore size distribution (1989)

This paper highlights the theory and operation of a method for measuring flow-weighted pore size distributions. This method is accomplished by measuring the flow of a mixture of an inert and a condensable gas under specific conditions. The partial pressure of the condensable gas is varied to produce capillary condensation, which plugs the pores of the membrane. At each pressure, the flow of the gas mixture is measured. The change in flow rate between pressures is then related to the pore size through the Kelvin equation for capillary condensation. Data giving accurately measured pore size distribution are extremely important when one attempts to understand the function of a porous material. Pore size distributions are usually determined by measuring the change in volume of a material deposited in the porous material under varying conditions that relate to pore size. A flow-weighted pore size distribution should provide information more meaningful for understanding the performance of a membrane. Pore size distributions measured on several commercially available membranes are shown. 2 refs., 5 figs.
Authenticated Mobile Device Proxy Service (2007)

In the current study we present a system that is capable to deliver proxy based differentiated service. It will help the carrier service node to sell a prepaid service to clients and limit the use to a particular mobile device or devices for a certain time. The system includes software and hardware architecture for a mobile device with moderate computational power, and a secure protocol for communication between it and its carrier service node. On the carrier service node a proxy runs on a centralized server to be capable of implementing cryptographic algorithms, while the mobile device contains a simple embedded processor capable of executing simple algorithms. One prerequisite is needed for the system to run efficiently that is a presence of Global Trusted Verification Authority (GTVA) which is equivalent to certifying authority in IP networks. This system appears to be of great interest for many commercial transactions, business to business electronic and mobile commerce, and military applications.
Aeroacoustic environment of an advanced STOVL aircraft in hover (1990)

The near-field aeroacoustic environment of a 6.02 pct scale advanced short takeoff and vertical landing aircraft is investigated in proximity to a simulated ground plane. The screech and impingement-tone characteristics of twin supersonic round and rectangular plumes are shown to be highly dependent on nozzle geometry and height above the ground plane. Shadowgraph and laser-sheet flow visualization are used to clarify the flowfield mechanisms responsible for time-dependent loads due to screech, impingement tones, and unsteady impingement of the upwash on the fuselage undersurface. Detailed dynamic pressure measurements from an array of transducers on the fuselage confirms that fountain impingement is responsible for the greatest unsteady loading.
Molecular regulation of kidney development (2013)

Genetically engineered mice have provided much information about gene function in the field of developmental biology. Recently, conditional gene targeting using the Cre/loxP system has been developed to control the cell type and timing of the target gene expression. The increase in number of kidney-specific Cre mice allows for the analysis of phenotypes that cannot be addressed by conventional gene targeting. The mammalian kidney is a vital organ that plays a critical homeostatic role in the regulation of body fluid composition and excretion of waste products. The interactions between epithelial and mesenchymal cells are very critical events in the field of developmental biology, especially renal development. Kidney development is a complex process, requiring inductive interactions between epithelial and mesenchymal cells that eventually lead to the growth and differentiation of multiple highly specialized stromal, vascular, and epithelial cell types. Through the use of genetically engineered mouse models, the molecular bases for many of the events in the developing kidney have been identified. Defective morphogenesis may result in clinical phenotypes that range from complete renal agenesis to diseases such as hypertension that exist in the setting of grossly normal kidneys. In this review, we focus on the growth and transcription factors that define kidney progenitor cell populations, initiate ureteric bud branching, induce nephron formation within the metanephric mesenchyme, and differentiate stromal and vascular progenitors in the metanephric mesenchyme.
New Culture Medium for Maintenance of Tsetse Tissues and Growth of Trypanosomatids* (1977)

SYNOPSIS. A new culture medium (SM), based on the amino‐acid composition of tsetse hemolymph and containing fetal bovine serum, was designed for the maintenance of tsetse organs and the cultivation of various trypanosomatids. For optimum growth 20% (v/v) serum was required. The medium supported prolonged peristalsis of the alimentary tract and salivary glands of pre‐emerged Glossina morsitans morsitans. In established cultures, derived from bloodstream forms of pleomorphic Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense strains, inocula of ∼ 10 6 procyclics/ml yielded 4–5 × 10 7 organisms/ml after 4 or 5 days of incubation at 28 C. Bloodstream forms of a cloned monomorphic T. b. brucei strain were also able to transform into procyclics, which, however, multiplied at a lower rate, with maximum yields of ∼ 2 × 10 7 after 5 days. Cultures of Trypanosoma congolense and of a nearly monomorphic Trypanosoma brucei gambiense strains could be established in SM medium only in the presence of tsetse alimentary tract. The procyclic trypomastigotes of these species, adapted to SM medium and able to grow in it without Glossina organs, gave maximum populations of ∼ 4.5 × 10 7 cells/ml. Promastigotes of Leishmania donovani , cultivated routinely in a diphasic Table's medium, multiplied actively upon being transferred into SM medium, producing yields of ∼ 4 × 10 7 cells/ml.
A communication structure for a multiprocessor computer with distributed global memory (1983)

An experimental multiprocessor computer was designed and built in order to explore the feasibility of certain internal communication mechanisms. The system consisted of seven processing elements, each containing a part of the global memory connected to a local bus. For each processor the global memory is seen as one single, linearly addressable structure. The processing elements were all connected to a common, global bus, consisting of three separate busses in order to increase the capacity. A bus selection unit was designed, capable of making a unique bus selection for each request, within a fraction of a memory cycle. The experiments have shown that communication structures based on distributed global memory and global bus systems can be used efficiently for medium scale systems.
Retinoic Acid and Histone Deacetylase Inhibitor BML‐210 Inhibit Proliferation of Human Cervical Cancer HeLa Cells (2006)

Human papillomavirus (HPV) infection is believed to be the central cause of cervical cancer. The viral proteins E6 and E7 from high-risk HPV types prevent cells from differentiating apoptosis and inducing hyperproliferative lesions. Human cervical carcinoma HeLa cells contain integrated human papillomavirus type 18 (HPV-18). Retinoic acid (RA) is a key regulator of epithelial cell differentiation and a growth inhibitor in vitro of HeLa cervical carcinoma cells. Cellular responses to RA are mediated by nuclear retinoic acid receptors (RARs) and retinoid X receptors. On the other hand, histone deacetylase inhibitors have been shown to be chemopreventive agents for the treatment of cancer cells. In this article, we have examined the antiproliferative effect of RA and histone deacetylase inhibitor BML-210 on HeLa cells, and particularly the effects on protein expression that may be involved in the cell cycle control and apoptosis. Our data suggest that a combination of RA and BML-210 leads to cell growth inhibition with subsequent apoptosis in a treatment time-dependent manner. We confirm that BML-210 alone or in combination with RA causes a marked increase in the level of p21. The changes in the p53 level are under the influence of p38 phosphorylation. We also discovered that the histone deacetylase inhibitor BML-210 causes increased levels of anti-apoptotic protein Bcl-2 and phosphorylated p38 MAP Kinase; the latter link in cell cycle arrest with response to extracellular stimuli. Our results suggest that RA and BML-210 are involved in different signaling pathways that regulate cell cycle arrest and lead to apoptosis of HeLa cells.
Dynamic Scheduling with Process Migration (2007)

Process migration is essential for runtime load balancing. In Grid and shared networked environments, load imbalance is not only caused by the dynamic nature of underlying applications, but also by the fluctuation of resource availability. In a shared environment, tasks need to be rescheduled frequently to adapt the variation of resources availability. Unlike conventional task scheduling, dynamic rescheduling has to consider process migration costs in its formulation. In this study, we first model the migration cost and introduce an effective method to predict the cost. We then introduce a dynamic scheduling mechanism that considers migration cost as well as other conventional influential factors for performance optimization in a shared, heterogeneous environment. Finally we present experimental testing to verify the analytical results. Experimental results show that the proposed dynamic scheduling system is feasible and improves the system performance considerably.
A rapid and gentle method for isolation of genomic DNA from pathogenic Nocardia spp (1996)

The lack of simple and efficient methods for extraction of DNA from Nocardia spp. has hampered molecular manipulation of the DNA for diagnostic purposes. In the present study, a method for the rapid extraction of undegraded genomic nocardial DNA was established. Briefly, 14 pathogenic Nocardia strains were grown at 37 degrees C for 3 to 5 days in Sauton broth containing 0.05% Tween 80. Subsequently, the cultures were treated for 48 h with 1.2 mg of cycloserine per ml (final concentration). Cells were then harvested by centrifugation and treated with a lysis solution containing 3 mg of lysozyme per ml. This was followed by the addition of proteinase K and sodium dodecyl sulfate to final concentrations of 0.2 mg/ml and 0.5%, respectively, and incubation for 1 h at 50 degrees C. DNA was precipitated with isopropanol after phenol-chloroform-isoamyl alcohol extractions and RNase treated before being quantitated and analyzed by agarose gel electrophoresis. The average undegraded DNA yields obtained were 101 micrograms for Nocardia brasiliensis and 121 micrograms for N. asteroides. This DNA was suitable for restriction endonuclease digestion and PCR amplification, which are methods being applied to the characterization and diagnosis of slowly growing organisms such as Nocardia spp.
Thematic review series: Lipid Posttranslational Modifications. Geranylgeranylation of Rab GTPases (2006)

Rab GTPases require special machinery for protein prenylation, which include Rab escort protein (REP) and Rab geranylgeranyl transferase (RGGT). The current model of Rab geranylgeranylation proposes that REP binds Rab and presents it to RGGT. After geranylgeranylation of Rab C-terminal cysteines, REP delivers the prenylated protein to membranes. The REP-like protein Rab GDP dissociation inhibitor (RabGDI) then recycles the prenylated Rab between the membrane and the cytosol. The recent solution of crystal structures of the Rab prenylation machinery has helped to refine this model and provided further insights. The hydrophobic prenyl binding pocket of RGGT and geranylgeranyl transferase type-I (GGT-I) differs from that of farnesyl transferase (FT). A bulky tryptophan residue in FT restricts the size of the pocket, whereas in RGGT and GGT-I, this position is occupied by smaller residues. A highly conserved phenylalanine in REP, which is absent in RabGDI, is critical for the formation of the REP:RGGT complex. Finally, a geranylgeranyl binding site conserved in REP and RabGDI has been identified within helical domain II. The postprenylation events, including the specific targeting of Rabs to target membranes and the requirement for single versus double geranylgeranylation by different Rabs, remain obscure and should be the subject of future studies.
Automatic arrhythmia detection based on heart beat interval series recorded through bed sensors during sleep (2011)

A high frequency of cardiac arrhythmias has been reported in sleep disordered patients. In order to detect the presence of arrhythmia during sleep, cardiac activity needs to be monitored. Several devices exist able to provide reliable Heart Rate Variability (HRV) measures in a minimally-intrusive way. Hence, there is the need for the development of robust methods for arrhythmia detection based on HRV measures. In the present study a method for automatic arrhythmia detection based on the analysis of an inter-beat series was developed and validated on recordings coming from the MIT-BIH Arrhythmia Database. The method was also applied on a beat to beat interval series obtained from the ballistocardiographic (BCG) signal of one subject, which was recorded during sleep using an innovative bed sensor which allowed for a noncontact and unobtrusive recording. When compared to the results of arrhythmia detection performed on the electrocardiographic (ECG) signal (concurrently acquired using polysomnography) using Cardioline Cube HOLTER analysis software, our method achieved a sensitivity of 55.6%, a specificity of 94.7 % and an accuracy of 91.8%. Our results suggest that the bed sensor could represent a reliable tool to assist the clinician in arrhythmia detection. 1.
Dialkylamido‐titanjodide (1971)

Abstract Durch Reaktion von TiJ 4 mit Ti(NR 2 ) 4 wurden die Verbindungen (Me 2 N) 3 TiJ, (Me 2 N) 2 TiJ 2 , (Et 2 N) 3 TiJ und (Et 2 N) 2 TiJ 2 , dargestellt; Trijodide R 2 NTiJ 3 ließen sich nicht in reiner Form isolieren. Die neuen Verbindungen wurden durch Protonenresonanz‐ und Spektren im fernen Infrarot charakterisiert. In ihren Eigenschaften schließen sie sich an die bereits früher beschriebenen Bromide an.
The Traumatic Brain Injury Model System of Care at MossRehab (1998)

No abstract available.
Chemogenomic Strategies to Expand the Bioactive Chemical Space (2009)

Chemogenomics aims towards the systematic identification of small molecules that interact with the products of the genome and modulate their biological function. The establishment and expansion of a comprehensive ligand-target Structure-Activity Relationship matrix is following the elucidation of the human genome a key scientific challenge for the 21(st) century. Small chemical compounds are the first dimension of the ligand-target SAR matrix. Accordingly, the systematic expansion of the physically available and bioactive chemical space is a key objective of chemogenomics. The vital question is, how to enlarge the physically existing chemical space into the bioactive and drug-like spaces? Effective systematic expansion of the chemical space to reach a maximum of biological binding sites appears possible when conserved molecular recognition principles are the founding hypothesis for the design of the compounds. Such principles, including approaches focusing on target families, privileged scaffolds, protein secondary structure mimetics, co-factor mimetics, and DOS and BIOS libraries are summarized in this mini-review article.
Etiologic Factors in Diaper Dermatitis: The Role of Feces (1986)

While the etiology of diaper dermatitis in infants is complex, it is generally believed to involve an interaction between skin and irritants in feces and urine. Proteases and lipases were identified as the major irritants in the feces of infants, and bile salts were found to potentiate the damage produced by the action of fecal enzymes on skin. Fecal enzymes also increased the permeability of skin, thereby increasing potential susceptibility to other irritants in the diaper environment.
Deep Learning-Based Video Coding: A Review and A Case Study (2019)

The past decade has witnessed great success of deep learning technology in many disciplines, especially in computer vision and image processing. However, deep learning-based video coding remains in its infancy. This paper reviews the representative works about using deep learning for image/video coding, which has been an actively developing research area since the year of 2015. We divide the related works into two categories: new coding schemes that are built primarily upon deep networks (deep schemes), and deep network-based coding tools (deep tools) that shall be used within traditional coding schemes or together with traditional coding tools. For deep schemes, pixel probability modeling and auto-encoder are the two approaches, that can be viewed as predictive coding scheme and transform coding scheme, respectively. For deep tools, there have been several proposed techniques using deep learning to perform intra-picture prediction, inter-picture prediction, cross-channel prediction, probability distribution prediction, transform, post- or in-loop filtering, down- and up-sampling, as well as encoding optimizations. In the hope of advocating the research of deep learning-based video coding, we present a case study of our developed prototype video codec, namely Deep Learning Video Coding (DLVC). DLVC features two deep tools that are both based on convolutional neural network (CNN), namely CNN-based in-loop filter (CNN-ILF) and CNN-based block adaptive resolution coding (CNN-BARC). Both tools help improve the compression efficiency by a significant margin. With the two deep tools as well as other non-deep coding tools, DLVC is able to achieve on average 39.6\% and 33.0\% bits saving than HEVC, under random-access and low-delay configurations, respectively. The source code of DLVC has been released for future researches.