gebhart/patrepeval huggingface dataset:
수정 M-W모형을 이용한 축소도시(Shrinking City)의 주택수요분석 (2014)

그동안의 고성장 인구증가시대에서의 공급량만을 늘리는 주택정책은 출생률감소와 인구의 고령화, 그리고 가구분화로 인한 1, 2인 가구의 증가와 같은 최근의 사회현상을 반영하지 못하고 있다. 또한, 이러한 주택정책은 인구가 꾸준히 성장하고 있는 대도시를 중심으로 한 정책이다. 그렇다면 지금과 같이 인구증가율이 감소하고 있는 상황에서 대도시가 아닌 중·소도시의 도시계획 방향은 무엇일까? 구체적으로 대도시와 달리 인구가 감소 또는 정체되고 있는 도시의 주택 정책은 대도시와 어떻게 달라져야 하는가? 본 연구에서는 이러한 관점에서 도시의 주택수요를 분석하되, 인구가 증가하는 성장도시(GrowingCity)와 인구가 감소 또는 정체되고 있는 축소도시(Shrinking City)의 주택수요를 비교함으로서 주택정책에 필요한 시사점을 찾고자 한다. 연구결과를 종합하면, 인구가 지속적으로 감소하고 경제 활력이 성장도시보다 떨어지는 축소도시의 경우 가구의 주택소비가 정점에 이르는 연령대가 60대 후반으로, 성장도시는 80대 초반으로 나타났다. 그런데, 소득, 자산과 같은 경제변수와 가구주나이 65세 이상의 고령 1, 2인 가구더미와 청년 1, 2인 가구더미를 추가한 분석에서 축소도시는 약 5년에서 10년 정도 빠른 50대에, 성장도시는 약 20년에서 25년 정도 앞당겨진 50대 후반에서 60대 초반에 최대 주택수요를 나타내는 것으로 분석되었다. 이러한 결과는 65세 이상의 고령 1, 2인 가구 또는 청년 1, 2인 가구의 비율이 주택수요를 왜곡할 수 있음을 보여준다. 또한, 도시의 인구 및 경제학적 특성에 따라 가구의 주택수요가 차별화될 수 있음을 나타낸다. 따라서, 경제 확장기에서 바라보았던 도시정책 그리고 주택수요정책을 이제는 개별도시의 인구 및 경제구조여건에 맞추어 재조정해야 할 필요성이 있다.
Effects of D-Amino Acid Oxidase Inhibitor on the Extracellular D-Alanine Levels and the Efficacy of D-Alanine on Dizocilpine-Induced Prepulse Inhibition Deficits in Mice (2009)

D-Alanine, one of D-amino acids present in the mammalian brain, is a selective and potent agonist at the Nmethyl-D-aspartate (NMDA) receptors. Like D-serine, D-alanine is reported to be effective in the treatment of schizophrenia. However, orally given D-alanine is metabolized substantially by D-amino acid oxidase (DAAO), diminishing its oral bioavailability. In this study, we studied the effects of oral D-alanine administration with or without the novel DAAO inhibitor, 5-chloro-benzo[d]isoxazol-3-ol (CBIO), on the extracellular D-alanine levels in the brain and on the prepulse inhibition (PPI) deficits after administration of the NMDA receptor antagonist dizocilpine. Co-administration of CBIO (30 mg/kg) with D-alanine (100 mg/kg), but not D-alanine (100 mg/kg) alone, significantly attenuated dizocilpine (0.1 mg/kg)-induced PPI deficits in mice. The in vivo microdialysis study of the conscious and free moving mice revealed that co-administration of CBIO (30 mg/kg) significantly increased extracellular levels of D-alanine in the frontal cortex after oral administration of D-alanine (100 mg/kg). These findings suggest that co-administration of CBIO can increase the bioavailability of D-alanine after oral administration of D-alanine, and that co-administration of CBIO can enhance the efficacy of D-alanine on dizocilpine-induced PPI deficits. Therefore, combination of D-alanine and a DAAO inhibitor such as CBIO offers new therapeutic potential for treatment of schizophrenia.
A strategy for comparing alternative software development life cycle models (1988)

It is difficult to compare and contrast models of software development because their proponents often use different terminology, and the models often have little in common except their beginnings (marked by a recognition that a problem exists) and ends (marked by the existence of a software solution). A framework is provided that can serve: as a basis for analyzing the similarities and differences among alternate life-cycle models; as a tool for software engineering researchers to help describe the probable impacts of a life-cycle mode; and as a means to help software practitioners decide on an appropriate life-cycle model to utilize on a particular project or in a particular application area.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Two Light-Induced Processes in the Photoreceptor Cells of <i>Limulus</i> Ventral Eye (1971)

The dark-adapted current-voltage (I-V) curve of a ventral photoreceptor cell of Limulus, measured by a voltage-clamp technique, has a high slope-resistance region more negative than resting voltage, a lower slope-resistance region between resting voltage and zero, and a negative slope-resistance region more positive than 0 v. With illumination, we find no unique voltage at which there is no light-induced current. At the termination of illumination, the I-V curve changes quickly, then recovers very slowly to a dark-adapted configuration. The voltage-clamp currents during and after illumination can be interpreted to arise from two separate processes. One process (fast) changes quickly with change in illumination, has a reversal potential at +20 mv, and has an I-V curve with positive slope resistance at all voltages. These properties are consistent with a light-induced change in membrane conductance to sodium ions. The other process (slow) changes slowly with changes in illumination, generates light-activated current at +20 mv, and has an I-V curve with a large region of negative slope resistance. The mechanism of this process cannot as yet be identified.
Relaxation and critical strain for maximum In incorporation in AlInGaN on GaN grown by metal organic vapour phase epitaxy (2012)

Quaternary AlInGaN layers were grown on conventional GaN buffer layers on sapphire by metal organic vapour phase epitaxy at different surface temperatures and different reactor pressures with constant precursor flow conditions. A wide range in compositions within 30–62% Al, 5–29% In, and 23–53% Ga was covered, which leads to different strain states from high tensile to high compressive. From high-resolution x-ray diffraction and Rutherford backscattering spectrometry, we determined the compositions, strain states, and crystal quality of the AlInGaN layers. Atomic force microscopy measurements were performed to characterize the surface morphology. A critical strain value for maximum In incorporation near the AlInGaN/GaN interface is presented. For compressively strained layers, In incorporation is limited at the interface as residual strain cannot exceed an empirical critical value of about 1.1%. Relaxation occurs at about 15 nm thickness accompanied by strong In pulling. Tensile strained layers can be grown pseudomorphically up to 70 nm at a strain state of 0.96%. A model for relaxation in compressively strained AlInGaN with virtual discrete sub-layers, which illustrates the gradually changing lattice constant during stress reduction is presented.
Polymorphism in the protease‐activated receptor‐4 gene region associates with platelet activation and perioperative myocardial injury (2011)

Protease-activated receptors (PAR)-1 and -4 are the principal receptors for thrombin-mediated platelet activation. Functional genetic variation has been described in the human PAR1 gene, but not in the PAR4 gene (F2RL3). We sought to identify variants in and around F2RL3 and to determine their association with perioperative myocardial injury (PMI) after coronary artery bypass graft surgery. We further explored possible mechanisms for F2RL3 single nucleotide polymorphism (SNP) associations with PMI including altered receptor expression and platelet activation. Twenty-three SNPs in the F2RL3 gene region were genotyped in two phases in 934 Caucasian subjects. Platelets from 43 subjects (23 major allele, 20 risk allele) homozygous for rs773857 (SNP with the strongest association with PMI) underwent flow cytometry to assess PAR4 receptor number and response to activation by a specific PAR4 activating peptide (AYPGKF) measured by von Willebrand factor (vWf) binding and P-selectin release and PAC-1 binding. We identified a novel association of SNP rs773857 with PMI (OR = 2.4, P = 0.004). rs773857 risk allele homozygotes have significantly increased platelet counts and platelets showed a significant increase in P-selectin release after activation (P = 0.004). We conclude that rs773857 risk allele homozygotes are associated with risk for increased platelet count and hyperactivity.
Tumor treating fields (TTFields) delay DNA damage repair following radiation treatment of glioma cells (2017)

Administration of TTFields after RT increases glioma cells treatment efficacy possibly by inhibition of DNA damage repair. These preclinical results support the application of TTFields therapy immediately after RT as a viable regimen to enhance RT outcome. Phantom measurements and animal models imply that it may be possible to leave the transducer arrays in place during RT without increasing skin toxicities.
Structure-directed self-assembly of alkyl-aryl-ethylene oxide amphiphiles (2008)

Polyethylene/poly(ethylene oxide) diblock oligomers strongly phase separate and crystallize in lamellar structures. We synthesized exact length analogues that have a 1,4-disubstituted benzene ring inserted at the junction between the alkyl and PEO chains, and determined their solid-state structures. The n-alkyl chains are 14, 16, 18 or 20 carbons in length and the poly(ethylene oxide) chains 0 to 7 repeat units and are capped with methyl groups. Powder X-ray diffraction data indicate phase separation of the alkyl and ethylene oxide chains into lamellar structures with the benzene rings aligned in a planar array at the interface between the two blocks. For some compounds, an initially formed bilayer motif is transformed to an interdigitated structure upon annealing at higher temperatures. Scanning calorimetry and vibrational spectroscopy support independent crystallization of the two blocks. On cooling from the melt state, the alkyl chains crystallize first, followed by the poly(ethylene oxide) segments. Alignment of the aromatic ring via crystallization of the two blocks suggests a general approach for aligning polar molecules in nanometre-scale materials.
25 tips for getting along with your co-workers. (2006)

Each member of the medical practice staff has the responsibility to develop positive relationships with his or her colleagues. Getting along is part of the job. Many employees do not realize this or they lack the tools to build strong co-worker relationships. This article offers 25 specific strategies that will help the staff of a medical practice build positive co-worker relationships and avoid disputes. It describes ways each member of the team can improve communication skills and foster an atmosphere of respect. This article also suggests specific language employees can use with one another and several communication don'ts that can foil positive co-worker relationships. The 25 tips offered in this article can be the subject ofa staff meeting, used for new employee training, and printed in the medical practice's employee handbook.
Cyclophosphamide plus cis-platinum in combination: treatment program for stage III or IV ovarian carcinoma. (1982)

A randomized prospective comparison of treatment with cyclophosphamide and that with cyclophosphamide and cisplatinum, each in 21 patients with advanced ovarian cancer, has shown that the time to progression of tumor and the duration of survival were markedly improved in the patients receiving the combination chemotherapy. Cytoreductive surgery was performed in most of the patients in the study before the chemotherapy regimen was initiated. Second-look surgery was performed after a year of chemotherapy. The chemotherapy was administered on an outpatient basis, without excessive toxicity. At 2 years, 52.4% of the patients receiving combination therapy had no progression of tumor, whereas 9.5% had no progression of tumor inthe group of patients receiving a single alkylating agent. Survival at 2 years was 61.9% for the combination chemotherapy group and 19.0% for those treated with cyclophosphamide alone. The study demonstrates a striking superiority of combination chemotherapy over single-agent chemotherapy in patients with advanced ovarian cancer.
Noninvasive <i>in Vivo</i> Measurement of Venous Blood pH during Exercise Using Near-Infrared Reflectance Spectroscopy (2007)

Blood pH is an important indicator of anaerobic metabolism in exercising muscle. This paper demonstrates multivariate calibration techniques that can be used to produce a general pH model that can be applied to spectra from any new subject without significant prediction error. Tissue spectra (725 approximately 880 nm) were acquired through the skin overlying the flexor digitorum profundus muscle on the forearms of eight healthy subjects during repetitive hand-grip exercise and referenced to the pH of venous blood drawn from a catheter placed in a vein close to the muscle. Calibration models were developed using multi-subject partial least squares (PLS) and validated using subject-out cross-validation after the subject-to-subject spectral variations were corrected by mathematical preprocessing methods. A combination of standard normal variate (SNV) scaling and principal component analysis loading correction (PCALC) successfully removed most of the subject-to-subject variations and provided the most accurate prediction results.
Proposed ultralow-energy dual photonic-crystal nanobeam devices for on-chip N x N switching, logic, and wavelength multiplexing (2015)

Silicon-on-insulator Mach-Zehnder interferometer structures that utilize a photonic crystal nanobeam waveguide in each of two connecting arms are proposed here as efficient 2 × 2 resonant, wavelength-selective electro-optical routing switches that are readily cascaded into on-chip N × N switching networks. A localized lateral PN junction of length ~2 μm within each of two identical nanobeams is proposed as a means of shifting the transmission resonance by 400 pm within the 1550 nm band. Using a bias swing ΔV = 2.7 V, the 474 attojoules-per-bit switching mechanism is free-carrier sweepout due to PN depletion layer widening. Simulations of the 2 × 2 outputs versus voltage are presented. Dual-nanobeam designs are given for N × N data-routing matrix switches, electrooptical logic unit cells, N × M wavelength selective switches, and vector matrix multipliers. Performance penalties are analyzed for possible fabrication induced errors such as non-ideal 3-dB couplers, differences in optical path lengths, and variations in photonic crystal cavity resonances.
Conferences (1999)

Journal Article Conferences Get access Various Various Search for other works by this author on: Oxford Academic Google Scholar Logic Journal of the IGPL, Volume 7, Issue 4, July 1999, Pages 555–566, https://doi.org/10.1093/jigpal/7.4.555 Published: 01 July 1999
THE CVD OF TiB<sub>2</sub> PROTECTIVE COATING ON SiC MONOFILAMENT FIBRES (1991)

TiB2 protective coatings have been deposited on SiC monofilament by a CVD technique. The CVD coating process studied involved the formation of TiB2 on resistively heated SiC fibres from the chemical reaction of TiCl4, BCl3, H2 at reduced pressure in a cold wall reactor. The effects of temperature, pressure and input reactant gas ratio on the morphology and nature of the coatings were investigated. The efficiency of chemically vapour deposited TiB2 as protective coating to inhibit the fibre-matrix interaction in titanium metal matrix composites was also evaluated by incorporating coated fibres in Ti-6Al-4V using diffusion bonding.
Quelques hypothèses sur le splendidissimum corpus mercatorum Cisalpinorum et Transalpinorum (1989)

Walser Gerold. Quelques hypothèses sur le splendidissimum corpus mercatorum Cisalpinorum et Transalpinorum. In: Ktèma : civilisations de l'Orient, de la Grèce et de Rome antiques, N°14, 1989. pp. 89-93.
A New Reaction of Nitriles. V. Preparation of N-(2-Halo-1-ethyl)-amides<sup>1</sup> (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Reaction of Nitriles. V. Preparation of N-(2-Halo-1-ethyl)-amides1Robert M. Lusskin and John J. RitterCite this: J. Am. Chem. Soc. 1950, 72, 12, 5577–5578Publication Date (Print):December 1, 1950Publication History Published online1 May 2002Published inissue 1 December 1950https://pubs.acs.org/doi/10.1021/ja01168a060https://doi.org/10.1021/ja01168a060research-articleACS PublicationsRequest reuse permissionsArticle Views267Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Influence of Mildly Acidic pH Conditions on the Production of Lentiviral and Retroviral Vectors (2014)

Human immunodeficiency virus type 1-derived lentiviral vectors (LVs) are becoming major tools for gene transfer approaches. Several gene therapy clinical studies involving LVs are currently ongoing. Industrial production of clinical-grade LVs is therefore an important challenge. Some improvements in LV production protocols have already been possible by acting on multiple steps of the production process like transfection, cell culture, or media optimizations. Yet, the effects of physicochemical parameters such as pH remain poorly studied. Mammalian cell cultures are generally performed at neutral pH, which may not be the optimal condition to produce high quantities of LVs with optimal infectious properties. In this study, we showed that lentiviral transient production in HEK293T cells is inversely dependent on the pH value of the harvesting medium. Infectious and physical titers of LVs pseudotyped with GALVTR or VSV-G glycoproteins are enhanced by two- to threefold at pH 6 compared with neutral conditions. pH 6-produced LVs are highly infectious on cell lines but also on relevant primary target cells like hCD34+ hematopoietic stem/progenitor cells. GALVTR-LV particles produced at pH 6 are highly stable at 37 °C and resistant to multiple freeze-thaw cycles. Higher levels of expression of intracellular pr55gag polyproteins are observed within HEK293T producer cells cultured at pH 6. The positive effect of pH 6 conditions is also observed for moloney-derived retroviral vectors produced from NIH-3T3 fibroblasts, arguing that the mildly acidic pH effect is not limited to the lentivirus genus and is reproducible in various producer cell lines. This observation may help us in the design of more effective LV production protocols for clinical applications.
BIOLOGÍA REPRODUCTIVA DE DICHROSTACHYS CINEREA (L.) WIGHT & ARN. (MARABÚ). (I) EVALUACIÓN DE REPRODUCCIÓN POR SEMILLAS (2008)

Dichrostachys cinerea (L.) Wight & Arn. (sicklebush) is at the moment one of the most invasive Cuban weeds. The loss of natural and cattle lands by the invasion and establishment of this woody species has reached alarming proportions. The evaluation of reproductive characteristics of this species by seeds both in laboratory and field conditions has been the objective of this work. Seeds were collected from a population of D. cinerea located near Havana, to evaluate percentage and energy or germination speed or emergency in laboratory and field conditions, in Plant Heath Research Institute. Marabu seeds presented a germination and poliembryony respectively superior to 70% and 30% in laboratory conditions, with double, triple and quadruple poliembryony, and a germinative energy equal to five days. Maximum values of emergency were obtained when seeding was made superficially and the greater germinative energy was obtained in 5 cm of depth seeded at rainy time under field conditions, reproductive capacity is lost in depths superior to 15 cm.
Adaptive video streaming over HTTP through 4G wireless networks based on buffer analysis (2017)

One of the main challenges in video transmission is understanding and adapting to the varying network bandwidth. The traditional approach of bandwidth estimation is not accurate as there are many factors like congestion that can delay the arrival rate of the ping packet which may lead to a misconception that the bandwidth was low. Thus, the better approach to this problem will be to estimate the link conditions based on the buffer fullness. In this paper, a new system to support streaming of live and stored video through wireless network is proposed which is based on adaptive playback buffer management on the top of HTTP at the client. The buffer fullness is treated as a direct state variable that reflects the fluctuation of the network bandwidth. The buffer fullness estimation predicts the buffer status at a point in the future based on observations of the buffer over a stipulated period of time. The proposed algorithm uses non-linear exponential non-parametric regression for computing the decision parameter. A feedback message is then sent to the server in order to change the quality of the video stream for smoother video play at the client side. The synchronized update and feedback between the server and clients is achieved using HTTP protocol. During the experimentation with live video streaming, the proposed algorithm shows an improvement of 24.48% in average peak signal-to-noise ratio and 6.63% in average structural similarity index against the buffer underflow probability algorithm.
Measurements of Permittivity, Dielectric Loss Tangent, and Resistivity of Float-Zone Silicon at Microwave Frequencies (2006)

The complex permittivity and resistivity of float-zone high-resistivity silicon were measured at microwave frequencies for temperatures from 10 up to 400 K employing dielectric-resonator and composite dielectric-resonator techniques. At temperatures below 25 K, where all free carriers are frozen out, loss-tangent values of the order of 2times10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> were measured, suggesting the existence of hopping conductivity or surface charge carrier conductivity in this temperature range. Use of a composite dielectric-resonator technique enabled the measurement of materials having higher dielectric losses (or lower resistivities) with respect to the dielectric-resonator technique. The real part of permittivity of silicon proved to be frequency independent. Dielectric losses of high-resistivity silicon at microwave frequencies are mainly associated with conductivity and their behavior versus temperature can be satisfactory described by dc conductivity models, except at very low temperatures
Comparison of the Effect of Etomidate and Desflurane on Brain Tissue Gases and pH during Prolonged Middle Cerebral Artery Occlusion  (1998)

These results suggest that tissue hypoxia and acidosis are often observed during etomidate treatment and middle cerebral artery occlusion. Treatment with desflurane significantly increases tissue PO2 alone and attenuates acidotic changes to prolonged middle cerebral artery occlusion.