gebhart/patrepeval huggingface dataset:
The effects of a community-based pulmonary rehabilitation programme on exercise tolerance and quality of life: a randomized controlled trial (1997)

The present multicentre study evaluates the differences in efficacy between a 3 month rehabilitation programme including drug treatment, and a 3 month control period of drug treatment only, for asthmatic patients and patients with chronic obstructive pulmonary disease (COPD). The programme was run by physiotherapists in eight local practices, and included exercise training, patient education, breathing retraining, evacuation of mucus, relaxation techniques, and recreational activities. In a randomized controlled trial with a cross-over design, the effects of rehabilitation were evaluated 3 and 6 months after baseline measurements in terms of exercise tolerance and quality of life (QOL). Exercise tolerance was assessed using submaximal cycle ergometer tests and 6 min walking tests. QOL was evaluated by means of the Chronic Respiratory Disease Questionnaire (CRDQ). After 3 months, the patients who started with rehabilitation showed significant improvements in endurance time (421 s) and cardiac frequency (6 beats.min-1) during cycling, walking distance (39 m), and total CRDQ score (17 points) compared to the control group. These improvements were still significant after 6 months. Additional analysis indicated that the asthmatic patients and the patients with COPD responded to rehabilitation in a similar way, with the exception that there was a greater improvement in walking distance for asthmatics. Improvements in exercise tolerance were not significantly correlated with improvements in QOL. Rehabilitation of patients with asthma or chronic obstructive pulmonary disease in local physiotherapy practices improves exercise tolerance and quality of life.
A General Approach of Damping Torsional Resonance Modes in Multimegawatt Applications (2011)

In large-drive applications, load-commutated inverters (LCIs) are one of the most used technologies mainly because of their excellent reliability records. However, LCIs are known to generate interharmonics. They can interact with the mechanical system at torsional natural frequencies of the rotating train, on both the inverter and rectifier sides in weakly connected power systems, such as offshore oil and gas platforms. These interactions can lead to accelerated shaft fatigue, lifetime reduction, gear damage, and system blackouts. On the other hand, pulsewidth-modulated (PWM) voltage-source inverters (VSIs) are known to produce less torque ripple compared to LCIs. Consequently, VSIs are supposed to be less subject to exciting torsional resonances in mechanical shaft systems. Even with reduced torque ripple, mechanical failures have been consistently reported due to motor air-gap torques supplied by PWM drives. This paper is focused on solving torsional vibration issues. Due to system uncertainties, these issues cannot be excluded in the design phase of LCIs and VSIs for high-power applications. With regard to LCIs, the dc-link inductance is used as an integrated energy-storage unit. Motor and generator interactions are therefore decoupled. Excited eigenmodes on the grid side are damped with the rectifier; the inverter is driving the variable-speed motor. This approach is also successfully applied to damping resonance modes in the motor side. Simulation and selected experimental results on a 30-MW LCI system are provided to validate the proposed design approach. As for VSIs, a more general approach of damping or controlling excited shafts is proposed. This method is successfully applied using the dc-link capacitor as an integrated energy-storage source. This approach is used to optimize the design of new systems; otherwise, it is used to improve the performance of existing systems with minor modifications.
Intracellular Sodium Accumulation During Ischemia as the Substrate for Reperfusion Injury (1999)

To elucidate the role of intracellular Na+ kinetics during ischemia and reperfusion in postischemic contractile dysfunction, intracellular Na+ concentration ([Na+]i) was measured in isolated perfused rat hearts using 23Na nuclear magnetic resonance spectroscopy. The extension of the ischemic period from 9 minutes to 15, 21, and 27 minutes (at 37 degrees C) increased [Na+]i at the end of ischemia from 270.0+/-10.4% of preischemic level (mean+/-SE, n=5) to 348.4+/-12.0% (n=5), 491.0+/-34.0% (n=7), and 505.3+/-12.1% (n=5), respectively, whereas the recovery of developed pressure worsened with the prolongation of the ischemic period (95.1+/-4.2%, 84.3+/-1. 2%, 52.8+/-13.7%, and 16.9+/-6.4% of preischemic level). The kinetics of [Na+]i recovery during reperfusion was analyzed by the fitting of a monoexponential function. When the hearts were reperfused with low-[Ca]o (0.15 mmol/L) solution, the time constants of the recovery (tau) after 15-minute (8.07+/-0.85 minutes, n=5) and 21-minute ischemia (6.44+/-0.90, n=5) were significantly extended, with better functional recovery (98.5+/-1.4% for 15-minute [P<0.05]; 98.0+/-1.0% for 21-minute [P<0.05]) compared with standard reperfusion ([Ca]o=2.0 mmol/L, tau=3.58+/-0.28 minutes for 15-minute [P<0.0001]; tau=3.02+/-0.20 for 21-minute [P<0.0001]). A selective inhibitor of Na+/Ca2+ exchanger also decelerated the [Na+]i recovery, which suggests that the recovery reflects the Na+/Ca2+ exchange activity. In contrast, high-[Ca]o reperfusion (5 mmol/L) accelerated the [Na+]i recovery after 9-minute ischemia (tau=2.48+/-0.11 minute, n=5 [P<0.0001]) and 15-minute ischemia (tau=2.10+/-0.07, n=6 [P<0. 05]), but functional recovery deteriorated only in the hearts with 15-minute ischemia (29.8+/-9.4% [P<0.05]). [Na+]i recovery after 27-minute ischemia was incomplete and decelerated by low-[Ca]o reperfusion, with limited improvement of functional recovery (42. 5+/-7.9%, n=5 [P<0.05]). These results indicate that intracellular Na+ accumulation during ischemia is the substrate for reperfusion injury and that the [Na+]i kinetics during reperfusion, which is coupled with Ca2+ influx, also determines the degree of injury.
Postprandial Glycemic Excursions with the Use of a Closed-Loop Platform in Subjects with Type 1 Diabetes: A Pilot Study (2010)

The artificial pancreas provided comparable postprandial glycemic control to usual care.
Medical Marijuana for Digestive Disorders: High Time to Prescribe? (2014)

The use of recreational and medical marijuana is increasingly accepted by the general public in the United States. Along with growing interest in marijuana use has come an understanding of marijuana's effects on normal physiology and disease, primarily through elucidation of the human endocannabinoid system. Scientific inquiry into this system has indicated potential roles for marijuana in the modulation of gastrointestinal symptoms and disease. Some patients with gastrointestinal disorders already turn to marijuana for symptomatic relief, often without a clear understanding of the risks and benefits of marijuana for their condition. Unfortunately, that lack of understanding is shared by health-care providers. Marijuana's federal legal status as a Schedule I controlled substance has limited clinical investigation of its effects. There are also potential legal ramifications for physicians who provide recommendations for marijuana for their patients. Despite these constraints, as an increasing number of patients consider marijuana as a potential therapy for their digestive disorders, health-care providers will be asked to discuss the issues surrounding medical marijuana with their patients.
A Versatile Electronic Computer for Photoelectric Spectrochemical Analysis (1964)

An electronic system has been designed with which it is possible to make dynamic background corrections by modifying existing commercial direct-reading equipment. The resulting linear curves make practical the use of simple electronic analog computation equipment to automatically calculate analytical values The design and use of a versatile computer to carry out this function is described Its application to the spectrochemical analysis of clamshells for Ba, Mn, Na, and Sr is presented.
Electrodeposition of Metals from Organic Solutions (1957)

The electrodeposition of Mg from ether solutions of such Mg compounds as (a) halides, (b) aluminohydrides, (c) borohydrides, and (d) Grignard reagents was investigated. White, metallic deposits containing 90% Mg and 10% B were obtained from an ether solution of and . However, thick deposits could not be built up. An alloy (7% Mg, 93% Al) was obtained from a bath containing , , and . Electrodeposited alloys of Zr, Ti, or Be with Mg, obtained from hydride or borohydride baths, were stressed, treed, or powdery. The preparation and solubilities of some of the solutes are given.
Negative pressure wound therapy: past, present and future (2013)

Negative pressure wound therapy (NPWT), which was introduced as a commercial product (V.A.C. Therapy, KCI USA, Inc., San Antonio, TX) less than 20 years ago, has revolutionised the treatment of complex wounds. Indicated for wide variety of wound types, NPWT is an adjunctive therapy that can be used safely in a range of care settings. Current research indicates that there are four primary NPWT mechanisms of action: macrodeformation, microdeformation, fluid removal and environmental control of the wound. The interaction of the primary mechanisms results in secondary effects through cell signalling (e.g. granulation tissue formation, cell proliferation and modulation of inflammation). Better understanding of the mechanisms of action also provides insight into future directions for NPWT research that could create better solutions for patients with complex wounds.
Inhibition of intra-abdominal adhesions: fibrin glue in a long term model. (1993)

Fibrin glue is being used more frequently to assist in the control of surgical bleeding in the abdominal and thoracic cavities. Prior investigation at this institution has indicated that fibrin glue actually inhibits adhesion formation in the peritoneal cavity of rats up to the first week postoperatively. To ascertain whether this protective effect is borne out in the long term, a randomized study was performed in 42 rats. As in the initial study, bilateral circular peritoneal-muscular defects were created to induce adhesion formation. The right-sided defects were closed linearly with interrupted sutures, thus closing the peritoneum, and the left-sided defects were closed with a continuous suture placed circumferentially, leaving the peritoneal defect open. The rats were randomized to two groups. In 21 animals, the abdomen was closed with no further treatment. In the other 21 animals the defects were covered with fibrin glue made from 0.2 mL of human fibrinogen (31.5 g/L) from cryoprecipitate and 0.2 mL of bovine thrombin and calcium. All rats were killed at 30 days, and adhesions were graded on a scale of 0 to 4 by a blinded observer. In the control group, 15 of 21 rats had high grade adhesions to the closed defect compared with 3 of 21 in the experimental (fibrin glue) group (P = 0.0003). For the left-sided lesions, 16 of 21 animals in the control group had high grade adhesions compared with 2 of 21 animals in the experimental group (P = 0.0004).(ABSTRACT TRUNCATED AT 250 WORDS)
A MODIFIED NYLON BAG TECHNIQUE FOR DETERMINING APPARENT DIGESTIBILITIES OF PROTEIN IN FEEDSTUFFS FOR PIGS (1983)

A method for measuring protein digestibility of small feed samples was developed with growing pigs fitted with a single cannula in the duodenum. Feed was ground through a 0.8-mm mesh screen and 1-g samples were enclosed in 25 × 40-mm monofilament nylon bags (50-μm mesh). Following pre-digestion in vitro to simulate gastric digestion (0.01 N HCI; pepsin 1 g/L; 2.5 h), the bags were inserted into the small intestine via the duodenal cannula, recovered in feces within 48 h, frozen, lyophilized and analyzed for protein. Apparent protein digestibility of soybean meal and meat-and-bone meal were 88.1 and 80.9%, respectively, compared with 90.0 and 79.1, respectively, determined conventionally. Protein digestibility (nylon bag vs. conventional technique) for three barley samples were 63.2 vs. 65.2%, 62.8 vs. 67.6% and 62.3 vs. 67.5%. The pigs were fed a 16% crude protein grower diet during the nylon bag studies. Preliminary studies showed no recovery of nylon bags in feces, unless the pig was starved for 1 day, when these were administered via a gastric cannula. The nylon bag technique, when samples are inserted via the duodenal cannula, appears to be a promising approach for rapid determination of protein digestibilities in small samples of feedstuffs. Key words: Nylon bag, digestibility, protein, cannula, pigs
Content Infrastructure and Performance Optimization (2016)

The infrastructure of the content ecosystem plays an important role in the availability, scalability, and performance of the system. The infrastructure includes the hardware specifications of all environments. This chapter discusses various elements of infrastructure architecture such as sizing, deployment architecture, and disaster recovery setup. It then describes various aspects of content performance and various performance optimization techniques such as optimal content design, optimal workflow design, caching, database-level optimizations, content caching, monitoring and notification, infrastructure-level performance optimization, etc. Content management system (CMS) interacts with various other systems such as security systems, translation systems, services, metadata systems, etc. Hence, it is important to gather the complete set of requirements from all aspects. Once the requirements are elaborated, it should be reviewed and signed off on by all concerned stakeholders. The chapter concludes with a look at content performance key performance indicators (KPIs) and performance testing.
Algorithms for scheduling hard aperiodic tasks in fixed-priority systems using slack stealing (1994)

This paper discusses the problem of jointly scheduling hard deadline periodic tasks and hard deadline aperiodic tasks using fixed priority methods. The approach is based on the slack stealing algorithm developed by the authors, and it assumes that the periodic deadlines must all be met. The paper develops a hard aperiodic acceptance test algorithm for guaranteeing tasks at any priority level, and it corrects an error in the original guarantee algorithm presented in Ramos-Thuel and Lehoczky (1993). It is shown that there is no optimal priority assignment for hard aperiodic task, but guidelines are given for choosing a good priority assignment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Automated planning and scheduling for goal-based autonomous spacecraft (1998)

Automated planning and scheduling technology enables a new class of autonomous spacecraft. We describe our use of symbolic AI in planning systems, provide an overview of the spacecraft-operations domain, and discuss several past, ongoing, and future deployments of planning systems technology at NASA.
Improved saliency detection based on superpixel clustering and saliency propagation (2010)

Saliency detection is useful for high level applications such as adaptive compression, image retargeting, object recognition, etc. In this paper, we introduce an effective region-based solution for saliency detection. We first use the adaptive mean shift algorithm to extract superpixels from the input image, then apply Gaussian Mixture Model (GMM) to cluster superpixels based on their color similarity, and finally calculate the saliency value for each cluster using compactness metric together with modified PageRank propagation. This solution is able to represent the image in a perceptually meaningful way and is robust to over-segmentation. It highlights salient regions with full resolution, well-defined boundary. Experimental results show that both the adaptive mean shift and the modified PageRank algorithm contribute substantially to the saliency detection result. In addition, the ROC analysis demonstrates that our approach significantly outperforms five existing popular methods.
DYMS (Dynamic Matcher Selector) - Scenario-based Schema Matcher Selector. (2013)

Schema matching is one of the main challenges in different information system integration contexts. Over the past 20 years, different schema matching methods have been proposed and shown to be successful in various situations. Although numerous advanced matching algorithms have emerged, schema matching research remains a critical issue. Different algorithms are implemented to resolve different types of schema heterogeneities, including differences in design methodologies, naming conventions, and the level of specificity of schemas, amongst others. The algorithms are usually too generic regardless of the schema matching scenario. This situation indicates that a single matcher cannot be optimized for all matching scenarios. In this research, I proposed a dynamic matcher selector (DYMS) as a probable solution to the aforementioned problem. The proposed DYMS analyzes the schema matching scenario and selects the most appropriate matchers for a given scenario. Selecting matchers are weighted based on the parameter optimization process, which adopts the heuristic learning approach. The DYMS returns the alignment result of input schemas.
Integrilin, Intervention, and the Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy Trial. (1999)

Eptifibatide (Integrelin, Corr Therapeutics, South San Francisco, CA) is a cyclic heptapeptide competitive inhibitor of the platelet glycoprotein (GP) IIb/IIIa receptor that has a short half-life. The results of the initial dose-finding and phase III trials are reviewed and the ongoing Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) trial are described.
Software methodology for remote monitoring and control system (2002)

This paper describes the software methodology for remote monitoring and control system which uses remote automation technique. The software methodology includes the creation and compilation of the server application and the client application, setting and execution of remote automation connection manager, and finally testing and debugging of client and server applications. The prototype application of this technique is shown to produce encouraging results. It also offers several advantages such as easy implementation, allowing the activation of server application when there is successful connection and the execution of server application to be visible on the screen. Also, with this methodology, the server can be run as supervisory window.
Boundary-Aware Feature Propagation for Scene Segmentation (2019)

In this work, we address the challenging issue of scene segmentation. To increase the feature similarity of the same object while keeping the feature discrimination of different objects, we explore to propagate information throughout the image under the control of objects' boundaries. To this end, we first propose to learn the boundary as an additional semantic class to enable the network to be aware of the boundary layout. Then, we propose unidirectional acyclic graphs (UAGs) to model the function of undirected cyclic graphs (UCGs), which structurize the image via building graphic pixel-by-pixel connections, in an efficient and effective way. Furthermore, we propose a boundary-aware feature propagation (BFP) module to harvest and propagate the local features within their regions isolated by the learned boundaries in the UAG-structured image. The proposed BFP is capable of splitting the feature propagation into a set of semantic groups via building strong connections among the same segment region but weak connections between different segment regions. Without bells and whistles, our approach achieves new state-of-the-art segmentation performance on three challenging semantic segmentation datasets, i.e., PASCAL-Context, CamVid, and Cityscapes.
Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled sigma2-receptor ligands. (2006)

We were able to synthesize two (76)Br-radiolabeled compounds with a high yield and specific activity that target the sigma(2) receptor with high affinity and selectivity. The studies presented show that both of the flexible benzamide compounds can identify EMT-6 breast tumors in vivo. (76)Br-1 also has higher tumor-to-normal tissue ratios when compared with (76)Br-2 and (18)F-FLT. The high affinity and low nonspecific binding of (76)Br-1 indicates that it can be a potential PET radiotracer for imaging solid tumors.
An aptamer-based fluorescence biosensor for multiplex detection using unmodified gold nanoparticles (2012)

A novel aptamer-based fluorescence biosensor for multiplex detection using unmodified AuNPs is developed to detect adenosine, thrombin and cocaine. Besides, this strategy can be applied to detect other small molecule substances.
Source tunable array for ground roll reduction (STAGRR) (1987)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1987Source tunable array for ground roll reduction (STAGRR)Authors: John J. SallasJohn J. SallasGeophysical Service Inc.https://doi.org/10.1190/1.1892119 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1892119FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1987ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1987 Pages: 923 publication data© 1987 Copyright © 1987 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 07 Mar 2005 CITATION INFORMATION John J. Sallas, (1987), "Source tunable array for ground roll reduction (STAGRR)," SEG Technical Program Expanded Abstracts : 236-238. https://doi.org/10.1190/1.1892119 Plain-Language Summary PDF DownloadLoading ...
Involvement of Acetyl Choline in Settlement of Balanus amphitrite (2003)

The aim of the present study was to investigate the presence and distribution of cholinergic molecules in Balanus amphitrite cyprids and their possible involvement in settlement and adhesion. Acetylcholinesterase (AChE, the lythic enzyme of acetylcholine) activity was detected, for the first time, by biochemical and histoenzymological methods, in the thoracic muscles, gut wall and cement gland. The immunodetection of choline acetyltransferase-like (ChAT) molecules in the same area and in the neuropil of the central nervous system suggests the presence of a cholinergic innervation, and the involvement of acetylcholine in muscular contraction and cement gland exocytosis. The binding of FITC-conjugate alpha-bungarotoxin in the cement gland cells confirms the latter hypothesis. Acetylcholine involvement in the settlement process was also investigated by laboratory tests employing cholinergic antagonists and agonists. An increase of available acetylcholine due to the partial inhibition of AChE activity produced an increase in cyprid settlement. The data presented support the hypothesis that acetylcholine has a neurotransmitter/neuromodulator role in settlement and adhesion of barnacle cyprids.