gebhart/patrepeval huggingface dataset:
SAWs enable the advent of the signal microprocessor development station (2002)

The Signal MicroProcessor (SMP) is a software-controlled programmable processor IC chip for video and RF signals. The SMP has been developed to bring the power of programmable mathematical processing to high-speed analog electronic equipment in cases where the cost and power requirements of the high-speed analog-to-digital converters (ADCs) and ultra-high-speed digital processing present a problem. It is enabled by a technology called acoustic charge transport, which is used to provide the buffer memory for analog signals in a platform that can also implement the high-speed arithmetic operations. The SMP performs the function of an ADC, a digital signal processor with 128 multipliers, 128 adders, control circuitry, and a digital-to-analog converter all working with a 360 megasample/s throughput rate.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Prostaglandins Enhance Spread of Herpes Simplex Virus in Cell Cultures (1978)

Stimuli such as u.v. light or trauma which induce recurrence of herpes simplex may act by affecting virus replication in the skin. Such stimuli release pharmacologically active agents in the skin, including prostaglandins (PGs) such as PGE2. These agents, and other compounds which alter levels of adenosine cyclic monophosphate (cyclic AMP), were tested for their effect on the replication of herpes simplex virus (HSV) in Vero cells. Prostanglandin E2 (PGE2) and prostaglandin F2alpha both increase the size of HSV plaques; PGE2 also increases the yield of virus inoculated at low m.o.i. Moreover, inhibitors of prostanglandin synthesis decrease plaque size and inhibit the growth of virus inoculated at low m.o.i.; such inhibition can be partially overcome by adding PGE2. Analysis of the results suggest that prostaglandins can enhance cell-to-cell spread of HSV, but that cyclic AMP is probably not involved in this effect.
A Novel Prioritized Control Scheme Using Random Access Period Control for Wide Area Ubiquitous Wireless Networks (2008)

In wide area ubiquitous wireless networks, most wireless terminals (WTs) will transmit small amounts of data at comparatively long intervals. Therefore, each AP must be capable of accommodating a great many WTs. Moreover, this network is required to accommodate a variety of services; some services need to be prioritized. In this paper, we propose a novel prioritized control scheme that applies random access to wide area ubiquitous wireless networks. Two kinds of priority classes are considered; high priority (HP) class and low priority (LP) class. The transmission performance of HP class must be guaranteed regardless of LP class traffic situation. To meet this requirement, the proposed scheme isolates the random access (RA) periods of the two classes and controls the RA period for HP class according to the HP class traffic situation, which is predicted from the HP event notification history (event here means that a WT has HP traffic to send). This paper also clarifies the problems of the conventional scheme and reveals the transmission performance of the conventional and proposed scheme by computer simulation.
Crystal and molecular structures of flavonoids. (1988)

Flavonoids are a broadly distributed class of plant pigments, universally present in vascular plants and responsible for much of the coloring in nature. Because of their widespread occurrence in edible plants, flavonoids are an integral part of the human diet. Therefore, the effects of these substances on human nutrition and well-being are of considerable importance, in particular in cultures where they constitute a major portion of the diet. To understand their mechanisms of action in various cellular and enzyme systems, it is important to have knowledge of their molecular properties. Structural studies have shown the three-dimensional conformations of these natural plant products, delineating their conformational preferences, showing the influence of substituents on conformation and physical properties. The results of these studies show that a single flavonoid may have more than one response, depending on enzyme site. Analysis of these flavonoid structure-activity relationships has offered insight into their mechanisms of action and will be instrumental in the design of new drugs based on these natural products. Thus, their diverse effects endow the flavonoids with an immense capacity to contribute important new therapeutic agents for the treatment of disease.
Characterization of the acidic oligosaccharides assembled on the <i>Pichia pastoris</i>‐expressed recombinant kringle 2 domain of human tissue‐type plasminogen activator (1997)

The N-linked glycans assembled in Pichia pastoris on the recombinant kringle 2 domain of human tissue-type plasminogen activator (r-[K2tPA]) are composed of approx. 80% neutral and 20% charged species. After peptide:N4-(N-acetyl-beta-glucosaminyl)asparaginyl amidase-catalysed liberation of the oligosaccharides from the purified glycopeptide, the glycan mixture was resolved by HPLC on amino-silica-based resin. Oligosaccharide mapping of the resulting mixture by HPLC, gel filtration and time-of-flight matrix-assisted laser-desorption-ionization-with-delayed-extraction mass spectrometry (TOF-MALDI DE-MS) revealed that > 90% of the charged species consisted of a series of oligosaccharides possessing molecular masses that were consistent with a range of saccharides comprising phospho-Man10GlcNAc2-phospho-Man14GlcNAc2, with phospho-Man11GlcNAc2 representing the major species. The remaining material in the charged fraction contained identifiable phosphorylated glycans that were one or two mannose units shorter, and one to four mannose units longer, than those present in the above range of oligosaccharides. Treatment of the native charged glycan pool with alkaline phosphatase did not result in molecular-size alterations, showing that phosphomonoesters are not present. Mild acid hydrolysis of the glycans led to a decrease in the size of all charged glycans by one mannose residue, providing phospho-Man9GlcNAc2-phospho-Man13GlcNAc2. Following this procedure, treatment with alkaline phosphatase resulted in size decreases that were equivalent to the loss of one phosphate group from each glycan. This demonstrates that all charged glycans isolated contained phosphate in phosphodiester bonds to two mannose units. The present study shows that P. pastoris cells possess the capability of assembling phosphorylated glycans having the phosphate moiety present in phosphodiester linkages with two mannose units. These saccharides, like the neutral oligosaccharides, contain considerably smaller amounts of mannose than glycans present in other strains of yeast.
Dietary supplementation of young broiler chickens with <i>Capsicum</i> and turmeric oleoresins increases resistance to necrotic enteritis (2013)

The Clostridium-related poultry disease, necrotic enteritis (NE), causes substantial economic losses on a global scale. In the present study, a mixture of two plant-derived phytonutrients, Capsicum oleoresin and turmeric oleoresin (XT), was evaluated for its effects on local and systemic immune responses using a co-infection model of experimental NE in commercial broilers. Chickens were fed from hatch with a diet supplemented with XT, or with a non-supplemented control diet, and either uninfected or orally challenged with virulent Eimeria maxima oocysts at 14 d and Clostridium perfringens at 18 d of age. Parameters of protective immunity were as follows: (1) body weight; (2) gut lesions; (3) serum levels of C. perfringens α-toxin and NE B-like (NetB) toxin; (4) serum levels of antibodies to α-toxin and NetB toxin; (5) levels of gene transcripts encoding pro-inflammatory cytokines and chemokines in the intestine and spleen. Infected chickens fed the XT-supplemented diet had increased body weight and reduced gut lesion scores compared with infected birds given the non-supplemented diet. The XT-fed group also displayed decreased serum α-toxin levels and reduced intestinal IL-8, lipopolysaccharide-induced TNF-α factor (LITAF), IL-17A and IL-17F mRNA levels, while cytokine/chemokine levels in splenocytes increased in the XT-fed group, compared with the animals fed the control diet. In conclusion, the present study documents the molecular and cellular immune changes following dietary supplementation with extracts of Capsicum and turmeric that may be relevant to protective immunity against avian NE.
Current Epidemiology and Growing Resistance of Gram-Negative Pathogens (2012)

In the 1980s, gram-negative pathogens appeared to have been beaten by oxyimino-cephalosporins, carbapenems, and fluoroquinolones. Yet these pathogens have fought back, aided by their membrane organization, which promotes the exclusion and efflux of antibiotics, and by a remarkable propensity to recruit, transfer, and modify the expression of resistance genes, including those for extended-spectrum β-lactamases (ESBLs), carbapenemases, aminoglycoside-blocking 16S rRNA methylases, and even a quinolone-modifying variant of an aminoglycoside-modifying enzyme. Gram-negative isolates--both fermenters and non-fermenters--susceptible only to colistin and, more variably, fosfomycin and tigecycline, are encountered with increasing frequency, including in Korea. Some ESBLs and carbapenemases have become associated with strains that have great epidemic potential, spreading across countries and continents; examples include Escherichia coli sequence type (ST)131 with CTX-M-15 ESBL and Klebsiella pneumoniae ST258 with KPC carbapenemases. Both of these high-risk lineages have reached Korea. In other cases, notably New Delhi Metallo carbapenemase, the relevant gene is carried by promiscuous plasmids that readily transfer among strains and species. Unless antibiotic stewardship is reinforced, microbiological diagnosis accelerated, and antibiotic development reinvigorated, there is a real prospect that the antibiotic revolution of the 20th century will crumble.
Rhizosphere bacteria of<i>Costularia</i>spp. from ultramafic soils in New Caledonia: diversity, tolerance to extreme edaphic conditions, and role in plant growth and mineral nutrition (2012)

Rhizosphere bacteria were isolated from Costularia spp., pioneer sedges from ultramafic soils in New Caledonia, which is a hotspot of biodiversity in the South Pacific. Genus identification, ability to tolerate edaphic constraints, and plant-growth-promoting (PGP) properties were analysed. We found that 10(5) colony-forming units per gram of root were dominated by Proteobacteria (69%) and comprised 21 genera, including Burkholderia (28%), Curtobacterium (15%), Bradyrhizobium (9%), Sphingomonas (8%), Rhizobium (7%), and Bacillus (5%). High proportions of bacteria tolerated many elements of the extreme edaphic conditions: 82% tolerated 100 μmol·L(-1) chromium, 70% 1 mmol·L(-1) nickel, 63% 10 mmol·L(-1) manganese, 24% 1 mmol·L(-1) cobalt, and 42% an unbalanced calcium/magnesium ratio (1/16). These strains also exhibited multiple PGP properties, including the ability to produce ammonia (65%), indole-3-acetic acid (60%), siderophores (52%), and 1-aminocyclopropane-1-carboxylate (ACC) deaminase (39%); as well as the capacity to solubilize phosphates (19%). The best-performing strains were inoculated with Sorghum sp. grown on ultramafic substrate. Three strains significantly enhanced the shoot biomass by up to 33%. The most successful strains influenced plant nutrition through the mobilization of metals in roots and a reduction of metal transfer to shoots. These results suggest a key role of these bacteria in plant growth, nutrition, and adaptation to the ultramafic constraints.
Rapid determination of the vapor pressure of lubricating oils and hydraulic fluids (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRapid determination of the vapor pressure of lubricating oils and hydraulic fluidsRalph E. Jentoft, A. Aner. Carlstrom, and T. H. GouwCite this: Anal. Chem. 1968, 40, 6, 1014–1015Publication Date (Print):May 1, 1968Publication History Published online1 May 2002Published inissue 1 May 1968https://pubs.acs.org/doi/10.1021/ac60262a028https://doi.org/10.1021/ac60262a028research-articleACS PublicationsRequest reuse permissionsArticle Views298Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Glycerol eutectics as sustainable solvent systems (2010)

In this work the use of glycerol as a hydrogen bond donor in Deep Eutectic Solvents is studied. The physical properties of choline chloride mixtures with glycerol are quantified and it is shown that eutectic mixtures can circumvent some of the difficulties of using glycerol as a solvent viz. high viscosity and high melting point. The solvent properties are characterised using polarity parameters and the values are similar to other ionic liquids although it is shown that this procedure is a poor method of characterising Lewis basicity. The application of these liquids to the esterification of glycerol is used as a demonstration of the ability to tune a reaction with the quaternary ammonium halide acting as a quasi-protecting group. The liquids represent a sustainable way of preparing non-toxic, tuneable solvent systems.
Lookup with CAM Aided Hash Table (2009)

Hashing is popularly adopted when it comes to a large scale of IP flows. This paper mainly focused on the lookup performance of content addressable memory aided hash table (CAHT). High throughout is available with minimized average memory access number. By rational approximation, the paper provided the lower bound on average memory access number over CAHT. When the hash is perfect hash or nearly to the perfect hash, the lower bound is achieved. Through the analysis of some typical CAHT, the lower bound is validated. Further, simulation is coincidental to the theory model. With this lower bound and the overflow fraction of CAHT, we can evaluate the throughput and the capability of CAM, so chose the proper hashing scheme in the actual applications.
Towards Multi-policy Support for IaaS Clouds to Secure Data Sharing (2013)

Infrastructure as a service (IaaS) is a cloud service model that provides storage and computation services for users at a low price. A recent report from Gartner indicates that IaaS will be the fastest growing area among all of the cloud service models in the near future, and thus it is strongly env
Comparison of roll-to-roll replication approaches for microfluidic and optical functions in lab-on-a-chip diagnostic devices (2015)

Economically advantageous microfabrication technologies for lab-on-a-chip diagnostic devices substituting commonly used glass etching or injection molding processes are one of the key enablers for the emerging market of microfluidic devices. On-site detection in fields of life sciences, point of care diagnostics and environmental analysis requires compact, disposable and highly functionalized systems. Roll-to-roll production as a high volume process has become the emerging fabrication technology for integrated, complex high technology products within recent years (e.g. fuel cells). Differently functionalized polymer films enable researchers to create a new generation of lab-on-a-chip devices by combining electronic, microfluidic and optical functions in multilayer architecture. For replication of microfluidic and optical functions via roll-to-roll production process competitive approaches are available. One of them is to imprint fluidic channels and optical structures of micro- or nanometer scale from embossing rollers into ultraviolet (UV) curable lacquers on polymer substrates. Depending on dimension, shape and quantity of those structures there are alternative manufacturing technologies for the embossing roller. Ultra-precise diamond turning, electroforming or casting polymer materials are used either for direct structuring or manufacturing of roller sleeves. Mastering methods are selected for application considering replication quality required and structure complexity. Criteria for the replication quality are surface roughness and contour accuracy. Structure complexity is evaluated by shapes producible (e.g. linear, circular) and aspect ratio. Costs for the mastering process and structure lifetime are major cost factors. The alternative replication approaches are introduced and analyzed corresponding to the criteria presented. Advantages and drawbacks of each technology are discussed and exemplary applications are presented.
Thermal analysis with special reference to microtechniques (1971)

R. P. Miller, R. A. W. Hill, B. W. Rodger, J. P. Dixon and D. H. Brown, Proc. Soc. Anal. Chem., 1971, 8, 159 DOI: 10.1039/SA9710800159
Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome (2016)

This case report summarizes the first use of intravenous vitamin C employed as an adjunctive interventional agent in the therapy of <i>recurrent</i> acute respiratory distress syndrome (ARDS). The two episodes of ARDS occurred in a young female patient with Cronkhite-Canada syndrome, a rare, sporadically occurring, noninherited disorder that is characterized by extensive gastrointestinal polyposis and malabsorption. Prior to the episodes of sepsis, the patient was receiving nutrition via chronic hyperalimentation administered through a long-standing central venous catheter. The patient became recurrently septic with Gram positive cocci which led to two instances of ARDS. This report describes the broad-based general critical care of a septic patient with acute respiratory failure that includes fluid resuscitation, broad-spectrum antibiotics, and vasopressor support. Intravenous vitamin C infused at 50 mg per kilogram body weight every 6 hours for 96 hours was incorporated as an adjunctive agent in the care of this patient. Vitamin C when used as a parenteral agent in high doses acts "pleiotropically" to attenuate proinflammatory mediator expression, to improve alveolar fluid clearance, and to act as an antioxidant.
Fuzzy controllers for semi-active suspension system generated through genetic algorithms (2002)

This paper presents two new methods to generate fuzzy controllers through genetic algorithms (GAs). The main difference between them lies in the initial state of the GAs. This means whether or not to use experts' knowledge for the fuzzy controllers. The method without the knowledge focuses on finding appropriate fuzzy control rules. The other focuses on selecting adequate combinations of input variables, which are usually determined a priori by the designer of the controller in the conventional methods. To set it performance index is the only procedure for the designer of the controllers. In both methods, parameters for the membership functions are tuned through the genetic operations. These parameters are encoded into the chromosomes. A new approach called GA with a local improvement mechanism is applied to the authors' methods. The comparisons with other conventional GAs are also discussed. The authors' approach shows superiority when particular parts of the chromosome have special meanings. To verify the effectiveness of the authors' approach, generation of fuzzy controllers for a semi-active suspension system is simulated.
Computer-Aided Orthopedic Surgery with Near-Real-Time Biomechanical Feedback (2004)

his article describes our ongoing efforts in computer-aided surgery. We are developing and testing a biomechanical guidance system that will interact with the surgeon and report the biomechanical state of the joint during hip surgery. The system uses information from the imagery of a computer-assisted navigation system and displays the contact pressure distribution in the hip joint as the joint realignment is modifi ed intraoperatively. We describe the use of the presented technique for preoperative planning, assessment of surgical outcome, and validation of results as well as intraoperative applications. Although the focus of this work is on periacetabular hip osteotomy, applications of this research can be extended to other types of hip osteotomies, joint osteotomies, and total joint replacement techniques.
A demonstration of the ottertune automatic database management system tuning service (2018)

Database management systems (DBMSs) have a plethora of tunable knobs that control almost everything in the system. The performance of a DBMS is highly dependent on these configuration knobs, however, getting this tuning right is hard. Many organizations resort to hiring experts to configure these knobs, but this is prohibitively expensive. As databases grow in both size and complexity, optimizing a DBMS has surpassed the abilities of even the best human experts. We recently introduced OtterTune, a tuning service that is able to automatically find good settings for a DBMS's configuration knobs. OtterTune leverages data collected from previous tuning efforts to train machine learning models, and recommends new configurations that are as good as or better than ones generated by existing tools or a human expert. In this demonstration, we showcase OtterTune's ability to automatically select a configuration that improves a DBMS's performance.
Evaluation of an optically coupled CCD digital radiography system (2005)

A digital radiography system comprised of a large field of view (43x43cm) high luminance CsI scintillator, optically coupled to a 4096x4096 element CCD sensor with 12:1 demagnification was evaluated by measuring the modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE). Detector evaluation was performed using IEC standard #62220-1 methodologies for beam quality. In this study, RQA-5 (21 mm Al added filtration, 74 kVp, 7.1 mm half value layer (HVL)) and RQA-9 (40 mm Al added filtration, 119 kVp, 11.5 mm HVL) qualities were used at several incident exposures from <0.1 mR to >50 mR. Two detector modes of operation included high resolution (HR) and high efficiency (HE), with 108 and 216 μm pixel dimensions, respectively. The detector system responded to 60 mR incident exposure prior to saturation for the HR mode and up to 30 mR in the HE mode. The pre-sampled MTF(<i>f</i>) had 50% modulation at 0.95 mm<sup>-1</sup> (HR) and 0.85 mm<sup>-1</sup> (HE); and 10%MTF(<i>f</i>) was reached at 2.4 mm<sup>-1</sup> (HR) and 2.0 mm<sup>-1</sup> (HE). At a frequency of 0.5 mm<sup>-1</sup>, the DQE was 40% to 50%, and at 1 mm<sup>-1</sup> was 12% to 20% for HR and HE modes, respectively. The DQE at low exposures was substantially better for the HE mode. Little dependence of the DQE on beam energy was found, but the RQA 9 beam had lower values. Above a frequency of 2 mm<sup>-1</sup> the DQE dropped to zero, attributed to low MTF. Results suggest that patient radiation exposures equivalent or better than a conventional 400 speed screen-film detector can be achieved for many imaging procedures with sufficient SNR and spatial resolution required for a wide range of diagnostic radiography applications.