gebhart/patrepeval huggingface dataset:
Effects of Dermatan Sulfate, a Heparin Cofactor II Mediated Thrombin Inhibitor, on the Endotoxin-Induced Disseminated Intravascular Coagulation Model in the Rat: Comparison With Low-Molecular Weight Heparin, Nafamostat Mesilate and Argathroban (1998)

Effects of dermatan sulfate (DS) on the endotoxin-induced disseminated intravascular coagulation (DIC) rat model were compared with those of low-molecular weight heparin (LMWH), nafamostat mesilate (NM) and argathroban (AR). At doses of 5, 10 or 20 mg/kg/4 hr, DS significantly ameliorated the decrease of fibrinogen (Fbg), the increase of fibrin-fibrinogen degradation products (FDP) and except at the highest dose (20 mg/kg/4 hr), the prolongation of thrombin clotting time (TCT). It also decreased the glomerular fibrin deposits (%GFD) at doses of 10 or 20 mg/kg/4 hr. LMWH suppressed the decrease of Fbg and the increase of FDP at doses of 1.4 or 2.8 mg/kg/4 hr. Only the highest dose of LMWH suppressed the decrease of the platelet count (PL), the prolongation of prothrombin time, and improved the %GFD. AR suppressed the decrease of PL and improved the %GFD. At the dose required to improve the %GFD, DS (5, 10 mg/kg/4 hr) significantly suppressed the prolongation of TCT, which is related to the bleeding frequency, while LMWH and AR further increased the prolongation of the TCT. These results suggest that DS has potential as a therapeutic drug with a lower hemorrhagic risk as compared with LMWH and AR in the treatment of DIC.
Rapid Assessment of Exposure to Chlorine Released from a Train Derailment and Resulting Health Impact (2007)

The rapid investigation revealed significant morbidity and mortality associated with an accidental release of chlorine gas. Key findings that should be addressed during facility, community, state, and regional mass-casualty planning include self-transport of symptomatic people for medical care and impact on health-care facilities over a wide geographic area.
An energy efficient garbage collector for java embedded devices (2005)

This paper presents a detailed design and implementation of a power-efficient garbage collector for Java embedded systems. The proposed scheme is a hybrid between the standard mark-sweep-compact collector available in Sun's KVM and a limited-field reference counter. There are three benefits resulting from the proposed scheme. (a) the proposed scheme reclaims memory more efficiently and this results in less mark-sweep garbage collection invocations, (b) reduction in garbage collection invocations improves cache locality and reduces the number of main memory accesses, and (c) reduction in memory access ultimately results in lower energy consumption, since a memory access can consume a large amount of energy when compared with an instruction execution. The proposed scheme has been implemented into Sun's KVM, and has been shown to reduce the number of mark-sweep garbage collection invocations by up to 100% in some cases, and the number of level-1 cache misses by as much as 87% when compared to the default garbage collector. We also find that in some applications, the proposed scheme can reduce the power consumption by as much as 27% when compared to the default Sun's KVM.
Automatic Recognition Of Wideband Telephone Speech With Limited Amount Of Matched Training Data (2014)

Publication in the conference proceedings of EUSIPCO, Lisbon, Portugal, 2014
ESTUDIO DE LA RED VIARIA ROMANA DE HISPANIA MEDIANTE TECNOLOGÍAS SIG: LAS PLANIMETRÍAS DE LA 1ª EDICIÓN DEL MTN 1/50.000 DE ESPAÑA, UNA CAPA DE INFORMACIÓN IMPRESCINDIBLE PARA EL INVESTIGADOR. (2012)

Los Sistemas de Informacion Geografica constituyen una potentisima herramienta para explorar la configuracion de la red viaria existente en epocas preteritas, cuyas posibilidades en dicho sentido apenas han sido explotadas hasta la fecha. La comunicacion que se trata tiene por objeto describir un proyecto SIG especificamente disenado para investigar el desarrollo de la red viaria de la meseta septentrional de Hispania durante la Edad Antigua. En una primera parte de la misma se detalla la estructura del proyecto, asi como el contenido y utilidad de las distintas capas de informacion que lo integran, dedicandose una especial atencion a incidir sobre el insustituible papel jugado en la investigacion por las planimetrias realizadas con motivo de la elaboracion de la 1a edicion del Mapa Topografico Nacional de Espana a escala 1/50.000. Finalmente, se resenan algunos de los resultados obtenidos hasta el presente momento mediante las investigaciones realizadas.
Part I: Satisfying internal customers: The link to external customer satisfaction (1992)

In the Eighties, U.S. business learned important new skills for identifying and satisfying external customers. Inevitably, this experience led to a recognition that the needs of internal work processes and internal customers were critical to external service delivery. The Conference Board and the Hay Group's conferences “Satisfying Internal Customers” held in New York and recently in San Diego, explored how enhancements in internal systems, processes, and activities can support improved external customer service. The presentations offered different perspectives on how companies manage the relationship between internal and external customer service. For example, some innovative companies focus on one internal customer relationship or core process, while others recognize numerous internal customer relationships and core processes to which each department or function must respond.
Transient up-regulation of P2Y<sub>2</sub>nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes (1997)

In studies designed to understand the roles of P2 nucleotide receptors in differentiation of T lymphocytes, we observed a transient and protein synthesis-independent enhancement of mRNA expression for the G protein-coupled P2Y2 receptor in mouse thymocytes after the addition of steroid hormone or T cell receptor (TCR) crosslinking by anti-TCR mAb. Conversely, dexamethasone-induced increases in mRNA expression for the ligand-gated ion channel P2X1 receptor was detected in rat, but not mouse, thymocytes, raising questions about the previously suggested role of P2X1 receptors in thymocyte apoptosis. Flow cytometry analysis of thymocyte subsets excluded the possibility that the observed increases in P2Y2 receptor mRNA expression were due to the enrichment of steroid-treated cells with an P2Y2 mRNA-rich thymocyte subset. Triggering of TCR-mediated intracellular signaling pathways through crosslinking of TCR or by addition of phorbol ester and Ca2+ ionophore also resulted in the up-regulation of P2Y2, but not P2X1, receptor mRNA. It is proposed that the rapid increase of P2Y2 receptor mRNA expression could be a common early event in responses of T cells to different activating stimuli. Taken together with the recently discovered ability of nucleotide receptor-initiated signaling to antagonize or enhance the effects of TCR crosslinking or steroids on thymocytes, the observed rapid up-regulation of P2Y2 receptor mRNA expression may reflect an immediate early gene response where newly expressed cell surface nucleotide receptors provide regulatory feedback signaling from extracellular ATP in the T cell differentiation process.
A Brief History of Intrauterine Pressure Measurement (1984)

In 1861 the development of obstetrical forceps to measure the degree of uterine expulsive forces gave impetus to investigations of uterine physiology. Although many methods were devised, the intrauterine balloon, used in the first successful attempt to evaluate activity of the gravid uterus in 1872, remained the standard by which other methods were judged. Alternate methods (such as the open catheter technique, hysterosalpingography, electrouterography, and external hysterography) were limited by cumbersome equipment, inaccurate gauges, difficulty in construction, excessive uterine irritation, and restriction of patient movement. A century of technological improvements in the intrauterine balloon and transducers made possible pioneering work in understanding the activity of the nongravid uterus, the concept of the rhythm method of birth control, carbon dioxide in the determination of tubal patency, and hormonal effects on reproduction and ovulation. Finally, understanding uterine contractile malfunction has given rise to the rational treatment of patients with dysmenorrhea.
Two-Dimensional Generalized Partial Response Equalizer for Bit-Patterned Media (2007)

The use of bit-patterned media is one of the approaches being investigated to extend magnetic recording densities to 1 Tbit/in <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and beyond. In patterned media, track pitch may be small causing adjacent tracks to have significant interference on the replay waveform from the main data track. To mitigate the effect of such inter-track interference (ITI), we propose the use of a two-dimensional (2D) generalized partial response (GPR) equalizer. We select both the equalizer and the partial response target using the minimum mean squared error (MMSE) criterion. However, we avoid the need for a 2D Viterbi algorithm by imposing a constraint on the 2D target that forces the adjacent track contributions (in the ideal case) to zero. Simulation results show that this 2D equalizer significantly improves the bit error rate (BER). In this work, the effect of a 2D GPR equalizer on the performance of a patterned media system in the presence of track misregistration (TMR) is also investigated. Based on the simulation results, the 2D equalization method appears to be more tolerant to TMR than the conventional GPR The main drawback of the proposed method is the need for simultaneously acquiring the signals from three adjacent tracks.
Regression-Based Summarization of Email Conversations (2009)

In this paper we present a regression-based machine learning approach to email thread summarization. The regression model is able to take advantage of multiple gold-standard annotations for training purposes, in contrast to most work with binary classifiers. We also investigate the usefulness of novel features such as speech acts. This paper also introduces a newly created and publicly available email corpus for summarization research. We show that regression-based classifiers perform better than binary classifiers because they preserve more information about annotator judgements. In our comparison between different regression-based classifiers, we found that Bagging and Gaussian Processes have the highest weighted recall.
Analysis of 9-fluorenylmethoxycarbonyl (FMOC) loading of solid-phase synthesis resins by gas chromatography (1998)

Base-catalyzed cleavage of the 9-fluorenylmethoxycarbonyl (FMOC) group and subsequent analysis by UV spectrophotometry is commonly employed to measure the "loading" of functional groups on solid support. Recent work suggests that 1,8-diazabicyclo[5.4. 0]undec-7-ene (DBU) may be superior to piperidine (the most commonly used base for the cleavage) for quantitative analysis by UV. We have compared deprotection of FMOC-bearing compounds by both DBU and piperidine, and have observed by GC-MS the formation of a dibenzofulvene-piperidine adduct (piperidine deprotection), and the formation of unassociated dibenzofulvene (DBU deprotection). We have further been able to use GC analysis of dibenzofulvene produced in the DBU deprotection mixture in a quantitative analysis of resin loading, which gave results comparable to UV methods. Sample preparation for this method has been automated using the Nautilus 2400 organic synthesizer to reduce the amount of operator time and increase throughput of sample analysis. Copyright 1998 John Wiley & Sons, Inc.
A CT method to measure hemodynamics in brain tumors: validation and application of cerebral blood flow maps. (2000)

The dynamic CT method presented herein provides absolute CBF measurements in brain tumors that are accurate and precise. Preliminary CBF maps derived with this method demonstrate their potential for depicting areas of different blood flow within tumors and surrounding tissue, indicating its possible use in the clinical setting.
Reliable End-to-End APNs interaction framework (2014)

Most of the admission control algorithms treat every admission request uniformly and hence optimize the system performance by maximizing the number of admitted and served requests. In practice, requests might have different levels of importance to the system. Requests offering high contribution or reward to the system performance deserve priority treatment. Failure of accepting a high-priority request would incur high penalty to the system. Our Proposed framework takes three priority classes of requests. The network capacity is divided into three partitions based on the threshold values: one for high class of requests and second for low class of request and third is common pool which accept the high, low and other classes of requests respectively. We take a condition in common pool if common pool is filled ¾ of its total capacity and at this time new request comes then we degrade the low priority class and accept that coming request. Reward and penalty are adopted in the proposed system model. High-priority requests are associated with higher values of reward as well as penalty than low-priority ones. In this paper, we have used these characteristics of the system in access provider network to admit more requests and to increase workload without degradation of system performance. Our proposed framework will improve the processing of the system model and optimize the system performance based on the objective function of the total reward minus the total penalty. The negotiation mechanism reduces the QoS requirements of several low-priority clients, by cutting out a small fraction of the assigned capacity, to accept a new high-priority client and to achieve a higher net earning value for enhancing the system performance.
Pausible clocking: a first step toward heterogeneous systems (2002)

This paper describes a novel communication scheme, which is guaranteed to be free of synchronization failures, amongst multiple synchronous modules operating independently. In this scheme, communication between every pair of modules is done through an asynchronous FIFO channel; communication between a module and the FIFO is done using a request/acknowledge handshaking. Synchronization of handshaking signals to the local module clock is done in an unconventional way-the local clock built out of a ring oscillator is paused or stretched, if necessary, to ensure that the handshaking signal satisfies setup and hold time constraints with respect to the local clock. We constructed a test bed consisting of two synchronous modules with pausible clocking control and an asynchronous FIFO on a MOSIS 1.2 /spl mu/m CMOS chip. The resulting system functions reliably up to the local clock frequency of 220 MHz (according to SPICE simulation)-the maximum clock rate is limited by the ring oscillator not the pausible clocking control. Preliminary test results indicate that the fabricated chips operate correctly as simulated.
Solvent Effects in Alternating ADMET Polymerization (2012)

Alternating AB copolymers were synthesized by exploiting the selectivity of the metathesis reaction between α,ω-dienes and α,ω-diacrylates. Unlike standard acyclic diene metathesis (ADMET) polymerizations, the copolymerization of dienes and diacrylates does not require high vacuum conditions. This work utilizes this unique characteristic to explore the effect of various solvents on ADMET polymerization. We found significant variation in the efficacy of the solvents we screened, with CH<sub>2</sub>Cl<sub>2</sub> yielding the highest molecular weight polymer. Additionally, the performance of Grubbs second generation catalyst was compared with Hoveyda-Grubbs second generation catalyst in different solvents, revealing a stark difference in the molecular weight of the resulting polymers in CH<sub>2</sub>Cl<sub>2</sub> but a relatively minor difference in the final molecular weight from polymerizations in acetic acid.
PLL with PI, PID and Fuzzy Logic Controllers based shunt Active Power Line Conditioners (2010)

This paper presents a novel Phase Locked Loop (PLL) circuit in conjunction with Proportional Integral (PI) or Proportional Integral Derivative (PID) or Fuzzy Logic Controller (FLC) based shunt Active Power Line Conditioners (APLC) for the power-quality improvement such as current harmonics and reactive power compensation due to the non-linear/unbalanced loads. The shunt APLC system is implemented with three phase current controlled Voltage Source Inverter (VSI) and is connected at the point of common coupling for compensating the current harmonics by injecting equal but opposite filter currents. The compensation process is based on PLL synchronization with PI or PID or fuzzy logic controller. These controllers are capable of controlling dc-side capacitor voltage and estimating reference currents. Hysteresis Current Controller (HCC) is used to generate switching signals for the voltage source inverter. Extensive simulation studies under different non-linear and unbalanced load conditions are conducted, this simulation results analysis reveals that the APLC system performs perfectly with PI, PID and fuzzy logic control strategy. A comparative assessment of the three different controllers has been disclosed.
Reduction in Eddy Current Loss in Conductor Using Magnetoplated Wire (2007)

Coil resistance is broken down into DC resistance, resistance due to the skin effect and resistance due to the proximity effect. Most of the coil resistance is composed of resistance due to the proximity effect in the high-frequency range. Thus, the resistance due to the proximity effect, which is equal to the eddy current loss, must be reduced. The eddy current loss in a magnetoplated wire is smaller than that in a copper wire. The magnetoplated wire is a copper wire whose circumference is plated with a magnetic thin film. The eddy current losses in magnetoplated wire can be analyzed using the finite element method. However, the analysis time is long and there is a memory capacity restriction when using the finite element method. In this study, we derive the expressions of the skin effect and eddy current loss in a magnetoplated wire for ease of calculation. The result shows that eddy current loss in the magnetoplated wire is reduced to a factor of 0.25 or less in comparison with that in copper wire, and that the resistance of the magnetoplated wire can be reduced due to the proximity effect.
3.77-5.05-μm tunable solid-state lasers based on Fe/sup 2+/-doped ZnSe crystals operating at low and room temperatures (2006)

Spectroscopic properties and lasing of Fe:ZnSe and co-doped Fe:Cr:ZnSe crystals in the mid-infrared spectral range were studied at room and low temperatures. Using a free-running Er:YAG laser as a pump source, the output energy of the thermoelectrically cooled Fe:ZnSe laser was 142 mJ with 30% slope efficiency at T=220 K. Passive Q-switched oscillation of Er:YAG laser with Fe:ZnSe crystal was demonstrated and used as a pump source for a Fe:ZnSe laser system. Room-temperature (RT) gain-switched lasing of Fe:ZnSe was achieved in microchip and selective cavity configurations using Q-switched Er:YAG and Raman-shifted Nd:YAG lasers as pump sources. The microchip laser threshold of 100 mJ/cm/sup 2/ was demonstrated using a Fe:ZnSe crystal without any reflection coatings. A slope efficiency of 13%, oscillation threshold of 1.3 mJ, and tunable oscillation of Fe:ZnSe laser systems over 3.95-5.05 /spl mu/m spectral range were realized at RT.
pELMO, an optimised in-house cloning vector (2017)

DNA cloning is an essential tool regarding DNA recombinant technology as it allows the replication of foreign DNA fragments within a cell. pELMO was here constructed as an in-house cloning vector for rapid and low-cost PCR product propagation; it is an optimally designed vector containing the ccdB killer gene from the pDONR 221 plasmid, cloned into the pUC18 vector's multiple cloning site (Thermo Scientific). The ccdB killer gene has a cleavage site (CCC/GGG) for the SmaI restriction enzyme which is used for vector linearisation and cloning blunt-ended products. pELMO transformation efficiency was evaluated with different sized inserts and its cloning efficiency was compared to that of the pGEM-T Easy commercial vector. The highest pELMO transformation efficiency was observed for ~500 bp DNA fragments; pELMO vector had higher cloning efficiency for all insert sizes tested. In-house and commercial vector cloned insert reads after sequencing were similar thus highlighting that sequencing primers were designed and localised appropriately. pELMO is thus proposed as a practical alternative for in-house cloning of PCR products in molecular biology laboratories.
Ultra-sensitive immunoassay biosensors using hybrid plasmonic-biosilica nanostructured materials (2014)

We experimentally demonstrate an ultra-sensitive immunoassay biosensor using diatom biosilica with self-assembled plasmonic nanoparticles. As the nature-created photonic crystal structures, diatoms have been adopted to enhance surface plasmon resonances of metal nanoparticles on the surfaces of diatom frustules and to increase the sensitivity of surface-enhanced Raman scattering (SERS). In this study, a sandwich SERS immunoassay is developed based on the hybrid plasmonic-biosilica nanostructured materials that are functionalized with goat anti-mouse IgG. Our experimental results show that diatom frustules improve the detection limit of mouse IgG to 10 pg/mL, which is ˜100× better than conventional colloidal SERS sensors on flat glass. Ultra-sensitive immunoassay biosensor using diatom biosilica with self-assembled plasmonic nanoparticles.
A built-in self-test for ADC and DAC in a single-chip speech CODEC (2002)

Built-in self-test (BIST) has been applied to test an analog to digital converter (ADC) and a digital to analog converter (DAC) embedded in a DSP-core ASIC. The performance characteristics of the ADC and the DAC designed in according with the CCITT recommendations are measured using BIST. Three characteristics have been evaluated and the measured results have shown good agreement with measured results by conventional tests. In the BIST operation, the DSP-core generates input stimulus and analyzes output response. Therefore, test-time is reduced, analog or mixed-signal test equipment is not needed, and finally, test-cost is reduced compared with conventional test methods. This paper describes the BIST design and evaluational results.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Primary antiphospholipid syndrome with acute myocardial infarction recanalised by PTCA (1998)

A 20 year old man with severe chest pain was hospitalised for acute myocardial infarction. Coronary angiography revealed total obstruction of his right coronary artery, which was successfully recanalised by direct percutaneous transluminal coronary angioplasty (PTCA). There was also diffuse thrombi in the left coronary artery that was not recanalised by perfusion with 3000 U pro-urokinase. Anticoagulant therapy was performed after PTCA. Creatine kinase peaked one day after hospitalisation (4805 U/l). The activated partial thromboplastin time was 62.6 seconds (45%). Plasma anticardiolipin IgG antibodies were high (3.8 and 2.7) in repeated examinations. The PTCA site was patent after three months. Primary antiphospholipid syndrome should be considered as a cause of acute myocardial infarction in young adults, and PTCA with anticoagulant treatment is effective for initial treatment of the syndrome.