gebhart/patrepeval huggingface dataset:
A family of design patterns for flexibly configuring network services in distributed systems (2002)

This paper describes a family of design patterns that enhance the flexibility and extensibility of communication software by permitting network services to evolve independently of the strategies used to passively initialize the services. The paper makes three contributions to the study and development of configurable distributed systems. First, it identifies five orthogonal dimensions of passive service initialization: service advertisement, endpoint listening, service handler creation, passive connection establishment, and service handler activation. Second the paper illustrates how a family of design patterns have been used to build a communication software framework that supports flexible configuration of different strategies for each of these five dimensions. Third, the paper demonstrates how design patterns and frameworks are being used successfully to develop configurable large-scale production distributed systems.
Spectral Shaping in Minimum Shift Keying (MSK)-Type Signals (1978)

Minimum shift keying (MSK)-type signals, while possessing all the advantages of MSK, allow input data pulse shaping in order to obtain more desirable spectral behavior. This paper presents a set of conditions on the pulse shape which enable an MSK-type signal to have a fast spectral rolloff. An <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">M</tex> th order shaping function, resulting in an asymptotic spectral falloff as <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">| f |^{-(4M + 4)}</tex> , is presented. Previously considered schemes such as MSK and sinusoidal frequency shift keying (SFSK) are shown to be special eases of this shaping function.
Mechanisms of sudden cardiac death (2005)

Despite recent advances in preventing sudden cardiac death (SCD) due to cardiac arrhythmia, its incidence in the population at large has remained unacceptably high. Better understanding of the interaction among various functional, structural, and genetic factors underlying the susceptibility to, and initiation of, fatal arrhythmias is a major goal and will provide new tools for the prediction, prevention, and therapy of SCD. Here, we review the role of aberrant intracellular Ca handling, ionic imbalances associated with acute myocardial ischemia, neurohumoral changes, and genetic predisposition in the pathogenesis of SCD due to cardiac arrhythmia. Therapeutic measures to prevent SCD are also discussed.
Functional characterization of agonists at recombinant human 5‐HT<sub>2A</sub>, 5‐HT<sub>2B</sub> and 5‐HT<sub>2C</sub> receptors in CHO‐K1 cells (1999)

1. The goal of this study was to characterize the agonist pharmacology of human 5-HT2A, 5-HT2B and 5-HT2C (VSV) receptors expressed in CHO-K1 (Chinese hamster ovary) cells. 2. We used a fluorometric imaging plate reader (FLIPR) which allows rapid detection of rises in intracellular calcium levels upon the addition of agonists. 3. Stimulation of all three receptors by 5-HT caused a robust concentration dependent increase in intracellular calcium levels. No such effect was observed from non-transfected control CHO-K1 cells. 4. The rank order of potency of agonists at the different receptor subtypes varied. Tryptamines, BW-723C86, d-norfenfluramine, Ro 60-0175 and LSD exhibited the following rank order of potency; 5-HT2B>5-HT2C>5-HT2A. Piperazines such as m-Chlorophenylpiperazine (mCPP), ORG-12962, MK-212 and also ORG-37684 exhibited a rank order of potency of 5-HT2C>5-HT2B>5-HT2A. The phenylisopropylamines DOI and DOB had a rank order of 5-HT2A>5-HT2B>5-HT2C. 5. Many agonists tested had partial agonist actions when compared to 5-HT, and a wide range of relative efficacies were exhibited, which was cell line dependent. For example, mCPP had a relative efficacy of 65% at 5-HT2C receptors but <25% at either 5-HT2A or 5-HT2B receptors. 6. Interpretation of literature values of functional assays using different cell lines, different receptor expression levels and different receptor isoforms, is complex. Species differences and the previous use of antagonist radioligands to characterize agonist potency in binding assays emphasizes the importance of studying agonists in the same experiment using the same assay conditions and parental cell lines.
Interference-aware scheduling in the multiuser MIMO-OFDM downlink (2009)

With the introduction of orthogonal frequency- division multiplexing and multiple antennas in cellular networks, there are new opportunities to adapt the transmission to propagation and interference conditions. In this article we describe a practical approach using space-frequency-selective multiuser MIMO scheduling. Frequency-selective feedback is provided on achievable data rates for preferred single- and multistream transmission modes. The base station selects the best mode while providing instantaneous fairness. We observe that multiuser transmission increases the probability of using multistream transmission. Besides the benefits from optimal combining at the physical layer, there is an additional gain at the MAC layer since the estimation of achievable rates becomes more precise. Altogether, 93 percent of the theoretical throughput can be realized by synchronizing the base stations and providing cell-specific reference signals. We have implemented essential functions of the approach in real time on an experimental 3GPP LTE prototype in 20 MHz bandwidth. Feasibility of the key features is proven in laboratory and field trials.
Preparation of High-T<sub>c</sub> Superconducting Films by Q-Switched YAG Laser Sputtering (1988)

A laser sputtering technique using visible light from a Q-switched YAG laser is proven to be of use for high- T c Y-Ba-Cu-O superconducting film fabrication. The obtained films reveal onset T c of 98 K and offset T c of 90 K, which are very similar to the bulk target material. The compositional ratios of Ba/Y and Cu/Y in as-sputtered films are found to be in perfect agreement with those in the bulk target material for a used laser power range. These results are well explained by a cluster model for the sputtering process.
Donors Thrombocytapheresis with Last Generation Cell Separators (1993)

An exciting, fast moving and promising field remains the use of plasma-free synthetic medium for platelet storage (10, 11), that along with the potential for getting more plasma for therapeutic needs, might also improve the quality of stored platelets. Addition of acetate to solution, may be the way to obtain these results. An astonishing fact is that citrate remains the only anticoagulant for platelet collection, and remains as well the only real cause of donor discomfort during thrombocytapheresis.
Efficient Automated Disease Diagnosis Using Machine Learning Models (2021)

Recently, many researchers have designed various automated diagnosis models using various supervised learning models. An early diagnosis of disease may control the death rate due to these diseases. In this paper, an efficient automated disease diagnosis model is designed using the machine learning models. In this paper, we have selected three critical diseases such as coronavirus, heart disease, and diabetes. In the proposed model, the data are entered into an android app, the analysis is then performed in a real-time database using a pretrained machine learning model which was trained on the same dataset and deployed in firebase, and finally, the disease detection result is shown in the android app. Logistic regression is used to carry out computation for prediction. Early detection can help in identifying the risk of coronavirus, heart disease, and diabetes. Comparative analysis indicates that the proposed model can help doctors to give timely medications for treatment.
Yield management: opportunities for private club managers (2002)

Yield management has been adopted by many hospitality organizations. An introduction to yield management concepts, resources and ideas for the design and implementation of price and capacity management tools is provided in the context of private club management. The use of contribution‐based yield statistics to monitor the performance of price and capacity decisions in high variable cost operations is discussed, along with reservations policies, perceptions of fairness and the use of coupons to obscure differential price policy.
Vertical ridge augmentation with autogenous bone grafts: resorbable barriers supported by ostheosynthesis plates versus titanium-reinforced barriers. A preliminary report of a blinded, randomized controlled clinical trial. (2007)

Both techniques were effective in augmenting bone; however, both were associated with complications. Clinicians and patients must carefully weigh risks and benefits when considering the use of vertical guided bone regeneration.
Clinical evidence for the activity of tetrahydroxypropyl ethylenediamine (THPE), a new anti-aging active cosmetic. (2011)

This clinical study demonstrated that the effect of a 2.5% THPE-containing cream on the keratinocytes cells leads to an immediate and long-term clinical improvement of the skin appearance (radiance and skin firmness, skin lifting) and can therefore be considered as a new anti-aging cosmetic active.
Designing Code Level Reusable Software ComponentsDesigning Code Level Reusable Software Components (2012)

The basic idea behind building Reusable software components is to design interchangeable parts from other industries to the software field of construction. A reuse library or component reuse repository organizes stores and manages reusable components. The biggest advantage of the building reusable software components is that it reduces the time and energy in developing any software. Frameworks provides a standard working system through which user 's main focus is on developing desired modules instead of developing lower level details. By using this facility the software developers can spend more time in developing the requirement of software, rather than preparing the tools of application development. Framework is set of reusable software program that forms the basis for an application. Frameworks help the programmers to build the application quickly .At its best code reuse is accomplished through the sharing of common classes and/or collections of functions, frameworks and procedures. This paper describes how to build the code level reusable components and how to design code level components. Finally providing coding guidelines, standards and best practices used for creating reusable code level components and guidelines and best practices for making configurable and easy to use.
Static Calibration and Dynamic Characterization of PMUs at NIST (2007)

This paper describes the development of two test systems at NIST aimed at improving the calibration and characterization of coordinated universal time (UTC) synchronized electric power instrumentation. Reference to UTC is used to meet the need for precise time synchronization of instrumentation designed to monitor the state of the grid over its wide geographic area. The first test system is used to perform calibrations of phasor measurement units (PMUs) for parameters that have performance requirements specified in IEEE standard for synchrophasors for power systems, IEEE standard C37.118-2005. Tests performed on this system use static electric power signals. The second test system is being developed to perform dynamic tests of PMUs. This paper also describes the development of a PMU testing guideline by an industry wide task force as part of the Eastern Interconnect Phasor Project (EIPP).
Cubic to Orthorhombic Diffusionless Phase Change— Experimental and Theoretical Studies of AuCd (1955)

A theoretical analysis of the cubic to orthorhombic transformation is presented which predicts for a partly transformed crystal, the interface plane, orientation relationships, and macroscopic distortions from a knowledge only of the lattice parameters of the initial and final phases. Arguments are advanced to show that in order to minimize the strain energy associated with the transformation, the interface plane must be one of zero average distortion. This leads directly to considerations of an inhomogeneous product phase. Experimental studies on an AuCd alloy are described and the observed crystallographic features of the transformation compared with values calculated using the theory. The agreement between calculated and observed results for this alloy system as well as others is strong evidence for the theory of diffusionless phase transformations presented.
Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas. (1998)

Although it is well-known that cancers show intratumoral phenotypic heterogeneity, genotypic studies have been scarce. Using comparative genomic hybridization and laser scanning cytometric analyses, we investigated intratumoral cytogenetic heterogeneity in 21 surgically removed gliomas including 11 glioblastomas (GBMs), 8 anaplastic astrocytomas (AAs) and 2 low-grade astrocytomas. Comparative genomic hybridization analysis revealed gain or amplification of 7p in 63%, gain of 7q in 73%, loss of 9p in 53%, loss of 10p in 47%, loss of 10q in 47%, loss of 13q in 53%, and loss of 22q in 37% of high-grade astrocytomas. Because these aberrations were region-independent within the same tumor, they did not contribute to intratumoral cytogenetic heterogeneity. Such heterogeneity was due to cytogenetic changes other than the above region-independent aberrations. Intratumoral cytogenetic heterogeneity was detected in 8 of 11 GBMs, 4 of 8 AAs, and none of the 2 low-grade astrocytomas. These observations suggest that cytogenetic changes at chromosomes 7, 9p, 10, 13, and 22 are primary events in high-grade astrocytomas and that subsequent cytogenetic changes involving increases in copy number provide intratumoral heterogeneity. DNA aneuploidy was detected by laser scanning cytometry in 5 of 11 GBMs and 1 of 8 AAs. All tumors with DNA aneuploidy exhibited intratumoral cytogenetic heterogeneity, and there was a significant correlation between DNA aneuploidy and intratumoral cytogenetic heterogeneity. These results support the notion that cytogenetic heterogeneity results from genetic instability within a tumor.
Functionalizing the Defects: Postsynthetic Ligand Exchange in the Metal Organic Framework UiO-66 (2016)

Herein, we explore the possibility of functionalizing UiO-66 with the monoethanolamine (MEA) moiety. Several unsuccessful routes are discussed before we show that it can be achieved via a 2 stage post synthetic ligand exchange (PSE) reaction with a highly defective UiO-66 sample. The intermediate material is the most porous UiO-66 sample ever reported. We expect that this novel approach will allow many other functional moieties to be introduced.
EFFECTS OF BOUNDARY CONDITIONS ON THE FLOW AND HEAT TRANSFER IN A ROTATING DISK CHEMICAL VAPOR DEPOSITION REACTOR (1987)

Numerical solutions of the Navier-Stokes and energy equations have been obtained to predict the fluid flow, temperature profiles, and heat transfer in a rotating disk reactor. The effects of buoyancy, variable properties, and finite geometry have been included for helium. It is shown that recirculation of the gas can be reduced or eliminated by increasing the uniform velocity at the inlet of the reactor above the asymptotic value for a one-dimensional, variable-properties, infinite rotating disk. This is true for both adiabatic and isothermal reactor walls. Furthermore, a cooled reactor wall as opposed to an adiabatic reactor wall is shown to result in dramatically altered velocity and temperature fields and reduced recirculation of the gas. When recirculation of the gas is reduced or eliminated the disk heat transfer that results is highly uniform and in good agreement with the one-dimensional, variable-properties, infinite rotating disk result. These results are useful for the design and operation of rotating disk reactors for chemical vapor deposition since in many cases the uniformity of the deposit is highly dependent on the uniformity of the heat transfer.
E. H. Carr, Winston Churchill, Reinhold Niebuhr, and US: The case for principled, prudential, democratic realism (1995)

(1995). E. H. Carr, Winston Churchill, Reinhold Niebuhr, and US: The case for principled, prudential, democratic realism. Security Studies: Vol. 5, Roots of Realism, pp. 314-353.
Evaluation of a silica‐containing bone graft substitute in a vertebral defect model (2009)

Orthopedic and spine surgeons are in need of supplements or replacements for autograft. We investigated the histological properties of three formulations of Calcium Sodium Phosphosilicate [calcium sodium phosphosilicate putty with or without autograft and NovaBone 45S5 Bioglass particulate (NovaBone, LLC, Jacksonville, FL)] using a sheep vertebral bone void model. Bone voids were surgically created in L3, L4, and L5 in each of 22 sheep, and the voids were filled with one of the tested biomaterials or left empty as a control. Histological evaluations were performed at either: 0, 6, or 12 weeks after surgery. Undecalcified sections were digitized, and the areas of the original defect and new bone were quantified. Decalcified sections were evaluated qualitatively. Histomorphometry showed a significant increase in the amount of bone between 6 and 12 weeks in all groups, but there was no significant difference in new bone formation among the formulations or between any formulation and the empty defects. The granules of all three formulations were associated with an inflammatory reaction. Many of the particles appear to have a hollow center, and the narrow tunnel through the center of the particles was sometimes associated with acute inflammation especially at 6 weeks. These particles were also associated with chronic inflammation at both 6 and 12 weeks, although the extent of inflammation decreased between 6 and 12 weeks. The search for the optimum bone graft substitute/extender will continue.
Backward Adaptive Reencoding: A Technique for Reducing the Bit Rate of µ-Law PCM Transmissions (1982)

This paper presents a technique for reducing the bit rate of μ-law PCM-coded speech from 8 bits/sample to a format of 6, 5, or 4 bits/sample. The particular format can be specified dynamically, i.e., it can be made to change from sample to sample. A device based on this technique has been designed using a 3 kbyte ROM and an uncommitted logic array (ULA) circuit to accommodate up to 96 multiplexed channels. The device can be set to operate in either the bit-rate-reducing mode, for removing the redundancy at the transmitter, or in the bit-rate-restoring mode, for recovering the standard PCM speech representation. The device finds useful applications in the context of multichannel telephony. In particular, it can be combined with digital speech interpolation to yield a three to four compression factor [2]. This technique provides approximately equivalent performances to the nearly instantaneous companding (NIC) technique [1] without the need for block processing, delay, or transmission of side information. The principle is based on the use of switched optimum reencoders (quantizers) selected by using a backward adaptation scheme. It further incorporates a redundancy reduction scheme [2], [3] which capitalizes on properties of both companded PCM and speech
Hypertension potentiates cataractogenesis in rat eye through modulation of oxidative stress and electrolyte homeostasis (2016)

Based on our findings, it can be concluded that systemic hypertension significantly increases the risk of cataract formation in the rat eyes via modulation of the antioxidant defense mechanism and electrolyte homeostasis.
The Distribution of Toxoplasma gondii Cysts in the Brain of a Mouse with Latent Toxoplasmosis: Implications for the Behavioral Manipulation Hypothesis (2011)

The observed pattern of T. gondii distribution stems from uneven brain colonization during acute infection and explains numerous behavioral abnormalities observed in the chronically infected rodents. Thus, the parasite can effectively change behavioral phenotype of infected hosts despite the absence of well targeted tropism.
Synthesis and STM Imaging of Symmetric and Dissymmetric Ethynyl‐Bridged Dimers of Boron–Subphthalocyanine Bowl‐Shaped Nanowheels (2012)

The future's wheel: A new class of wheels, based on subphthalocyanine fragments, for future incorporation in functional nanovehicles is reported (see figure). The syntheses of a symmetric wheel, a nitrogen-tagged wheel, and their ethynyl-bridged homodimers are presented. Theoretical calculations and STM imaging demonstrate the advantage of a bowl-shaped structure and the efficiency of the tag for STM imaging.
Relationships of Leaf Fatty Acids to Cold Hardening of Citrus Seedlings (1982)

Three cultivars of citrus with different sensitivities to freezing temperatures (citron, Citrus medica L.; rough lemon, C. limon Burm. F; sour orange, C. aurantium L.) were cold hardened for 4 weeks. Lipids from leaves of hardened and control seedlings were fractionated and analyzed for fatty acids. The absolute amount of triglycerides and phospholipids increased in the leaves upon hardening. With hardening, total linoleic acid also increased 141% in citron, 210% in rough lemon, and 233% in sour orange. Specific increases in linoleic acid were found in triglycerides, in the four phospholipids (phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylglycerol), and in neutral lipids more polar than triglycerides. Trans-3-hexadecenoic acid was found only in phosphatidylglycerol.
Petrology of The Alkaline Intrusive at Blue Mountain, Ontario (1939)

A large stock of alkaline rock is described quantitatively, and the mineral variations are shown on contoured distribution plans. Chemical analyses of albite, microline, and nepheline are presented, as well as chemical analyses of six of the type rocks. Field observations of the relationship to surrounding rocks are supplemented by age determinations based upon radioactivity. The latter indicate an age difference of the order of 500 million years between the feldspathoid rock and the younger granitic batholith, thus precluding the possibility of a genetic relationship between them. Based upon this and upon the lack of evidence of desilication of the intrusives by limestone, it is concluded that the limestone syntexis theory of origin of feldspathoid rocks is not tenable for the intrusive in question and seems unlikely for the Bancroft alkaline province as a whole. Analogy is drawn between the crystallization of the alkaline intrusive and that of a comparable artificial melt; it is concluded that the characteristics of the intrusive and the mineral variations can be reasonably attributed to crystallization of a magma approximately of the composition of the average rock. There is no evidence that the alkaline magma was developed by any special process operative in the zone of present observation.