gebhart/patrepeval huggingface dataset:
All-solution-processed inverted polymer solar cells with low temperature, water-processable hybrid electron-collecting layers (2012)

We herein report on a highly simple and efficient all-solution-processed inverted polymer solar cell (PSC), which consists of a bulk-heterojunction (BHJ) photovoltaic (PV) layer with a low-temperature, water-processable electron-collecting layer (ECL) made of a hybrid poly(ethylene oxide) (PEO) and cesium carbonate (Cs2CO3) compound. For the BHJ PV layer of poly(3-hexylthiophene):phenyl C61-butyric acid methyl ester (P3HT:PCBM) with the hybrid PEO:Cs2CO3 ECL and a solution-coated anode of silver nanoparticles (NPs), it was found that a power conversion efficiency (PCE) of around 2.5% could be achieved for PSCs fabricated entirely from solution in air at a low processing temperature below 150 °C, using the inverted structure on a glass substrate. This excellent PV performance may be attributed to efficient photo-generated charge-carrier collection, due to the suitable work function of the hybrid PEO:Cs2CO3 ECL used. Moreover, even for a fully solution-processed flexible inverted PSC on a plastic substrate, a relatively high PCE of 1.3% was obtained. The use of this hybrid ECL in all-solution-processable inverted PSCs could be of considerable benefit in the development of cost-effective and highly efficient all-solution- and roll-to-roll processed inverted PSCs.
<i>N,N</i>‘-Bisbenzylidenebenzene-1,4-diamines and<i>N,N</i>‘-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors (2006)

A series of N,N‘-bisbenzylidenebenzene-1,4-diamine and N,N‘-bisbenzylidenenaphthalene-1,4-diamine derivatives were synthesized as inhibitors for human sirtuin type 2 (SIRT2). The design of the new compounds was based on two earlier reported hits from molecular modeling and virtual screening. The most potent compound was N,N‘-bis(2-hydroxybenzylidene)benzene-1,4-diamine, which was equipotent with the most potent hit compound and well-known SIRT2 inhibitor sirtinol.
Detection, estimation, and modulation theory. Part 2 - Nonlinear modulations theory (1971)

Book on nonlinear modulation based on optimum estimation theory covering phase synchronization, analog data transmission, digital and analog systems performance, Markov processes, etc
Cooling Airflow in Unidirectional Ventilated Open-Type Motor for Electric Vehicles (2006)

In this paper, the cooling airflow in a unidirectional ventilated open-type motor for electric vehicles (EV) was studied. Numerical fluid analysis was performed on the airflow in the motor through a ventilation path outside the stator iron core inside the frame. It is confirmed that there was a flow separation where air did not flow along the path surfaces. This was observed in a flow visualization experiment using water instead of air. We propose a new structure to prevent air separation and confirm its effectiveness by a visualization experiment. It is also shown that another structure with paths both inside and outside the stator iron core in the frame improves the motor's cooling performance. These structures are effective for EV motor downsizing.
Variations in time of hospital presentation for deliberate self-harm and their implications for clinical services (2006)

BACKGROUND: Variation in number, characteristics and management of deliberate self-harm (DSH) patients presenting to hospital during the 24-h cycle and day of the week may have implications for patient services. We have investigated how patient characteristics and clinical management of DSH episodes vary according to hour and day of presentation. METHODS: Time of presentation was studied in 5348 DSH patients who presented to a general hospital following 9101 episodes during a 6-year period. Patient characteristics were identified through routine clinical monitoring. RESULTS: Presentations varied markedly during the 24-h cycle, ranging from a peak between 8 pm and 3 am (average hourly rate of 6.6% of all episodes) to a low between 4 am and 10 am (1.4%). The majority (72.0%) occurred outside office hours. DSH associated with alcohol use and interpersonal problems was more frequent during the late evening or night, and at the weekend. A greater proportion of daytime presentations involved high suicide intent (although a larger number of high intent acts presented at other times), and more were admitted and assessed. LIMITATIONS: This study was based on DSH presentations to one hospital. Time and date of presentation and of psychosocial assessment, not time of DSH, were available for analysis. CONCLUSIONS: Peak times for DSH presentations are at night and the weekend, suggesting that specialist DSH services in general hospitals should be available 24 h a day, 7 days a week. Time of presentation should not be used as a proxy measure of suicide intent.
Effects of NSAID on collagen and proteoglycan synthesis of cultured chondrocytes. (1989)

Three major NSAID (tiaprofenic acid, indomethacin and acetylsalicylic acid) were studied with regard to their effects on the biosynthesis and gene expression of collagen and proteoglycan of chondrocytes. We found that the biosynthesis of type 11 collagen was suppressed in 60-70% of the controls by either indomethacin or acetylsalicylic acid; tiaprofenic acid did not suppress collagen synthesis. Although the biosynthesis of proteoglycan was suppressed to 80-90% of the control by indomethacin or acetylsalicylic acid, tiaprofenic acid did not suppress proteoglycan synthesis. In order to investigate the gene expression of type 11 collagen and proteoglycan, dot blot hybridization was performed using type 11 collagen and proteoglycan cDNA. The effects of NSAID on the amount of type 11 collagen and proteoglycan mRNA were consistent with those on collagen and proteoglycan biosynthesis. Thus, we concluded that tiaprofenic acid has less effect on cultured chondrocytes.
A step toward GPS/INS personal navigation systems: real-time assessment of gait by foot inertial sensing (2005)

In this paper, we develop a system for which applications in the field of personal navigation are planned. In the current version, the system embodies a Global Positioning System (GPS) receiver and an inertial measurement unit (IMU), composed of two dual-axis accelerometers and one single-axis gyro. The IMU is positioned at a subject's foot instep, and it is intended to produce estimates of some gait parameters, including stride length, stride time, and walking speed. Data from GPS and IMU are managed by a DSP-based control box. The computations performed by the DSP processor allow to detect subsequent foot contacts by a threshold-based method applied to gyro signal, and to reconstruct the trajectory of the foot instep by numerical strapdown integration. Features of human walking dynamics are incorporated in the algorithm to enhance the estimation accuracy against errors due to sensor noise and integration drift. All computations are performed by the DSP processor in real-time conditions. The foot sensor performance is assessed during outdoor level walking trials. The traveled distance estimated by inertial dead-reckoning is compared with the estimate produced by GPS in experimental conditions where GPS can be used as a reference source for accurate absolute positioning. Results show the remarkable accuracy achieved by foot inertial sensing.
Taking Your Use of Word to the Next Level (2010)

In this chapter, I’ll show you how to take your use of Word to the next level—that of an advanced user. To this end, you’ll learn skills you can use either in a business situation or at home.
Mobile Mashup: Architecture, Challenges and Suggestions (2009)

Mashup combines multiple data sources to form some kind of new services. Using Mashup, service creation becomes more convenient, effective and low-cost with user's participation. In telecommunication industry, mobile Mashup assembles applications and data sources both from Internet and telecom network (here telecom network refers to mobile communication network.), mobile computing device capabilities are also involved. Mobile Mashup can take full advantages of the inherent predominance of telecom network to create content-rich services. Based on an ongoing research work cooperating with China Mobile, this paper explores the architecture, challenges and suggestions of mobile Mashup. The relatively high-level architecture of our mobile Mashup platform based on SOA design principle is presented. Involving telecom network and mobile computing resources into Mashup could bring in challenges such as data security, network security and data exchange efficiency between mobile devices and server side. We study on these challenges and some recommendations corresponding are discussed.
A Lymnaea stagnalis gene, with sequence similarity to that of mammalian beta 1–>4-galactosyltransferases, encodes a novel UDP-GlcNAc:GlcNAc beta-R beta 1–>4-N-acetylglucosaminyltransferase. (1994)

A cDNA encoding a novel glycosyltransferase, that may be involved in a variant pathway for the synthesis of complex type oligosaccharide chains, was cloned from the pond snail Lymnaea stagnalis. By heterologous hybridization, using bovine beta 1-->4-galactosyltransferase cDNA as probe, a genomic clone from a snail library was isolated. This genomic clone was subsequently used to clone the corresponding cDNA from a prostate gland library. The isolated cDNA encodes a polypeptide of 490 amino acids with a type II membrane protein topology typical for glycosyltransferases. The carboxyl-terminal part, encoding the putative catalytic domain, reveals considerable sequence similarity with the corresponding region of mammalian beta 1-->4-galactosyltransferases, suggesting an evolutionary relationship. Expression of this cDNA in COS cells and insect cells revealed that the encoded enzyme transfers GlcNAc, rather than Gal or GalNAc, from the corresponding nucleotide sugars to several beta-N-acetylglucosaminides. Structural characterization by 1H NMR spectroscopy of products formed in vitro demonstrated that the enzyme can be identified as a UDP-GlcNAc:GlcNAc beta-R beta 1-->4-N-acetylglucosaminyl-transferase. A new family of glycosyltransferases has hereby been discovered, consisting of enzymes that act on acceptor substrates with a terminal beta-linked GlcNAc residue and establish a beta 1-->4-linkage, but have a different nucleotide sugar requirement.
D2D Big Data Privacy‐Preserving Framework Based on (<i>a</i>, <i>k</i>)‐Anonymity Model (2019)

As a novel and promising technology for 5G networks, device‐to‐device (D2D) communication has garnered a significant amount of research interest because of the advantages of rapid sharing and high accuracy on deliveries as well as its variety of applications and services. Big data technology offers unprecedented opportunities and poses a daunting challenge to D2D communication and sharing, where the data often contain private information concerning users or organizations and thus are at risk of being leaked. Privacy preservation is necessary for D2D services but has not been extensively studied. In this paper, we propose an ( a , k )‐anonymity privacy‐preserving framework for D2D big data deployed on MapReduce. Firstly, we provide a framework for the D2D big data sharing and analyze the threat model. Then, we propose an ( a , k )‐anonymity privacy‐preserving framework for D2D big data deployed on MapReduce. In our privacy‐preserving framework, we adopt ( a , k )‐anonymity as privacy‐preserving model for D2D big data and use the distributed MapReduce to classify and group data for massive datasets. The results of experiments and theoretical analysis show that our privacy‐preserving algorithm deployed on MapReduce is effective for D2D big data privacy protection with less information loss and computing time.
Homogeneous Catalytic Hydrosilylation of Pyridines (1998)

The color change from yellow to violet allows the formation of the intermediate [Cp2Ti(SiHMePh)(pyridine)] to be monitored in the reaction of PhMeSiH2 with a pyridine in the presence of the precatalyst [Cp2TiMe2] [Eq. (a)]; the hydride [Cp2TiH] is postulated to be the key intermediate in the catalytic cycle. The regioselective hydrosilylation of pyridine and also substituted pyridines can be catalyzed by the titanocene [Cp2TiMe2]. R=Me, CO2Et.
Regulation of neutrophil inflammatory mediator release: chemotactic peptide activation of stimulus-dependent cytotoxicity. (1983)

Human neutrophils stimulated with phorbol myristate acetate (PMA) were able to damage human erythroleukemic K-562 target cells as assessed by a 3-hr 51Cr-release assay. Neutrophils from a patient with chronic granulomatous disease of childhood were ineffective in mediating PMA-stimulated cytolysis. Cytotoxicity was inhibited under anaerobic conditions as well as by catalase and several free radical scavengers. Superoxide dismutase, azide, and cyanide failed to inhibit PMA-dependent cytotoxicity. The influence of the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) on stimulus-dependent cytotoxicity was examined. Neutrophils preincubated with 1.0 X 10(-7) M FMLP did not display an increased cytotoxic response, but were markedly amplified in their ability to effect cytotoxicity with the addition of PMA. Enhancement of PMA-stimulated cytotoxicity resulted from a reversible cellular response to FMLP. The kinetics of the cytotoxic responses reflected the possibility that chemotactic peptide-treated neutrophils released cytotoxic mediators to a greater extent and at a faster rate than did untreated neutrophils. Although azide and superoxide dismutase did not inhibit cytotoxic responses of chemotactic peptide-activated neutrophils, the response was prevented by catalase and was markedly inhibited by several free radical scavengers. The ability of FMLP to enhance cytotoxic responses correlated well with its enhancement of PMA-stimulated chemiluminescence under a variety of conditions. In addition, the ability of PMA-stimulated neutrophils to mediate methane generation from dimethyl sulfoxide and ethylene generation from alpha keto-gamma-methiol-butyric acid (KMB)--assays that quantitate the generation of oxidizing radicals--was increased if the neutrophils were preincubated with FMLP. These results demonstrate that a chemotactic factor greatly potentiates the release of cytotoxic mediators from neutrophils upon stimulation with a nonchemotactic agent. The cytotoxic mediators appear to be products of oxidative metabolism. The cytotoxic potential of neutrophils that have responded to chemotactic stimuli to reach sites of inflammation may be activated in a similar manner.
DESIGN ASPECTS OF FELICE, THE FREE ELECTRON LASER FOR INTRA-CAVITY EXPERIMENTS (2002)

At the FOM Institute “Rijnhuizen” a new Free Electron Laser for Intra-Cavity Experiments (FELICE) is under development. In this article we describe the accelerator aspects of the project as it is seen at the moment.
Modeling and monitoring of cardiovascular dynamics for patients in critical care (2007)

In modern intensive care units (ICUs) a vast and varied amount of physiological data is measured and collected, with the intent of providing clinicians with detailed information about the physiological state of each patient. The data include measurements from the bedside monitors of heavily instrumented patients, imaging studies, laboratory test results, and clinical observations. The clinician’s task of integrating and interpreting the data, however, is complicated by the sheer volume of information and the challenges of organizing it appropriately. This task is made even more difficult by ICU patients ’ frequently-changing physiological state. Although the extensive clinical information collected in ICUs presents a challenge, it also opens up several opportunities. In particular, we believe that physiologically-based computational models and model-based estimation methods can be harnessed to better understand and track patient state. These methods would integrate a patient’s hemodynamic data streams by analyzing and interpreting the available information, and presenting resultant pathophysiological hypotheses to the clinical staff in an efficient manner. In this thesis, such a possibility is developed in the context of cardiovascular dynamics.
BangA: An Efficient and Flexible Generalization-Based Algorithm for Privacy Preserving Data Publication (2017)

Privacy-Preserving Data Publishing (PPDP) has become a critical issue for companies and organizations that would release their data. k-Anonymization was proposed as a first generalization model to guarantee against identity disclosure of individual records in a data set. Point access methods (PAMs) are not well studied for the problem of data anonymization. In this article, we propose yet another approximation algorithm for anonymization, coined BangA, that combines useful features from Point Access Methods (PAMs) and clustering. Hence, it achieves fast computation and scalability as a PAM, and very high quality thanks to its density-based clustering step. Extensive experiments show the efficiency and effectiveness of our approach. Furthermore, we provide guidelines for extending BangA to achieve a relaxed form of differential privacy which provides stronger privacy guarantees as compared to traditional privacy definitions.
A prototype of an AAL for high bit rate real-time data transmission system over ATM networks using a RSE CODEC (2000)

This work introduces a prototype of an ATM Adaptation Layer (AAL) with forward error correction (FEC) to serve the problems raised by high and variable bit rate real-time data transmission systems (for example studio/video applications) over ATM networks. To match the high bandwidth requirements at real-time and to minimize the implementation resources an encapsulated coding system is introduced. The coding system comprises a Reed Solomon Erasure (RSE) code, an interleaver and a CRC on cell level. The RSE is only capable of correcting cell-losses. Hence bit-errors are detected by the CRC and referenced as cell-losses. In using the RSE the benefits of ATM are exploited to improve FEC and the overall processing time becomes significantly small against conventional solutions. The prototype is implemented in Alteras FLEX10KE series FPGAs and the syntheses results are depicted.
CD8+ T Cells Cause Disability and Axon Loss in a Mouse Model of Multiple Sclerosis (2010)

In multiple sclerosis patients, CD8+ T cells outnumber CD4+ T cells in active lesions and the number of CD8+ T cells correlates with the extent of ongoing axon injury and functional disability. Our findings suggest that CD8+ T cells may directly injure demyelinated axons and are therefore a viable therapeutic target to protect axons and motor function in patients with multiple sclerosis.
Color difference ΔE : a survey (2011)

Color perception is crucial for human existence. This is why, color spaces have been developed to describe mathematically the color that a person can feel with unaided eye. There was a new need to ...
Light intensity profiles in a perfectly mixed photoreactor (1970)

Abstract The light intensity distribution in a perfectly mixed photoreactor has been studied experimentally and analytically. Experimental measurements of intensities within the reactor were made with a specially designed light probe. These data were then used to test the validity of a model which treats the ultraviolet lamp as a linear source radiating in all directions. It was found that this model, which seems appropriate and allows reasonable computations, is somewhat in error owing to the neglect of the finite size of the lamp and the existence of reflection and refraction effects within the reactor. An empirical correction function was determined for use with the model which then yields predictions in close agreement with experimental data when the reactor is filled with a light absorbing liquid.
Prolonged Assessment of Sleep and Daytime Sleepiness in Unrestrained Macaca Mulatta (2006)

Similarities in sleep architecture between M. mulatta and humans make this an excellent animal model for investigations of normal and pathologic human sleep. This study confirms and extends previous findings in nonhuman primates. Stable, high-quality data were obtained for months to years using a telemetric system capable of long-term data collection.
Encorafenib, Binimetinib, and Cetuximab in <i>BRAF</i> V600E–Mutated Colorectal Cancer (2019)

A combination of encorafenib, cetuximab, and binimetinib resulted in significantly longer overall survival and a higher response rate than standard therapy in patients with metastatic colorectal cancer with the <i>BRAF</i> V600E mutation. (Funded by Array BioPharma and others; BEACON CRC ClinicalTrials.gov number, NCT02928224; EudraCT number, 2015-005805-35.).
Pattern recognition of <sup>31</sup>P magnetic resonance spectroscopy tumour spectra obtained <i>in vivo</i> (1993)

Pattern recognition has been applied to the analysis of in vivo 31P NMR spectra. Using four different classes of tumour and three types of normal tissue, cluster analysis and artificial neural networks were successful in separating and classifying the majority of samples analysed. Although the phosphomonoester and P(i) regions appeared to be the most important spectral features, data representing the entire 31P spectrum were required for best separation of the tumour and tissue classes.
Decode-and-Forward Cooperative Diversity with Power Allocation in Wireless Networks (2007)

We study power allocation for the decode-and-forward cooperative diversity protocol in a wireless network under the assumption that only mean channel gains are available at the transmitters. In a Rayleigh fading channel with uniformly distributed node locations, we aim to find the power allocation that minimizes the outage probability under a short-term power constraint, wherein the total power for all nodes is less than a prescribed value during each two-stage transmission. Due to the computational and implementation complexity of the optimal solution, we derived a simple near-optimal solution. In this near-optimal scheme, a fixed fraction of the total power is allocated to the source node in stage I. In stage II, the remaining power is split equally among a set of selected nodes if the selected set is not empty, and otherwise is allocated to the source node. A node is selected if it can decode the message from the source and its mean channel gain to the destination is above a threshold. In this scheme, each node only needs to know its own mean channel gain to the destination and the number of selected nodes. Simulation results show that the proposed scheme achieves an outage probability close to that for the optimal scheme obtained by numerical search, and achieves significant performance gain over other schemes in the literature
Immunolocalization of osteonectin in avian tibial dyschondroplastic cartilage (1996)

Osteonectin is an acidic calcium-binding protein found in cartilage, bone matrix, vascular endothelium, and areas of tissue repair. Using immunocytochemistry, osteonectin has been localized in all zones of the normal avian epiphyseal growth plate with notably high amounts in the hypertrophic zone. In the proximal portion of this zone the staining was intracellular, while in the distal calcifying portion of the hypertrophic zone staining was both intracellular and extracellular. Osteonectin was also detected in the growth plate associated with lesions of chickens with tibial dyschondroplasia (TD). Intense intracellular staining was observed in hypertrophic chondrocytes proximal to the lesion; staining was markedly diminished in the TD lesion; extracellular matrix was devoid of staining. Staining intensity was high along the peripheral edges of the lesion that were undergoing vascularization and resorption. This was the only area in the dysplastic cartilage where staining was observed in the extracellular matrix as well as intracellularly. Similar patterns were viewed in all TD lesions examined, whether they were spontaneous or induced by dietary treatments or genetic selection.