gebhart/patrepeval huggingface dataset:
Singlet photochemistry in model photosynthesis: identification of charge separated intermediates by Fourier transform and CW-EPR spectroscopies (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSinglet photochemistry in model photosynthesis: identification of charge separated intermediates by Fourier transform and CW-EPR spectroscopiesKobi Hasharoni, Haim Levanon, Jau Tang, Michael K. Bowman, James R. Norris, Devens Gust, Thomas A. Moore, and Ana L. MooreCite this: J. Am. Chem. Soc. 1990, 112, 18, 6477–6481Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/ja00174a004https://doi.org/10.1021/ja00174a004research-articleACS PublicationsRequest reuse permissionsArticle Views208Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Brain-Derived Neurotrophic Factor in Plasma of Women with Endometriosis (2010)

Purpose Endometriosis is one of the most common benign gynecological diseases affecting women of reproductive age; it is characterized by the presence and growth of ectopic endometrial tissue outside the endometrial cavity. This complex disease is frequently associated with infertility and pelvic pain. Given the relationship and the apparent importance of the role that neurotrophins play in the reproductive system, and in particular brain-derived neurotrophic factor (BDNF) which is involved in both the central and peripheral pain pathways, we were interested in determining whether the presence of endometriosis is associated and correlated with plasma and follicular fluid variation of BDNF. Methods We determined BDNF level in plasma and in follicular fluid from infertile women with endometriosis and fertile women without the disease. Results BDNF plasma levels were significantly higher in endometriotic patients than in control women (p<0.001). After surgery this level decreased significantly (p<0.001), ranging within the values of control women in follicular phase. In follicular fluid, BDNF values were significantly lower in infertile women for endometriosis than in infertile women for male factors (p<0.001). Conclusion These data raise the possibility that neuroinflammatory reactions in endometriosis could have a neuroprotective effect and support the hypothesis that BDNF represents an important link in the networks of human homeostasis, thus providing an early marker for patients affected by endometriosis. Moreover, low BDNF levels in follicular fluid may refect an altered ovary production and may be a marker of poor oocyte quality and poor fertility in women suffering from endometriosis.
Granulocyte-Macrophage Colony-Stimulating Factor Delays Neutrophil Constitutive Apoptosis Through Phosphoinositide 3-Kinase and Extracellular Signal-Regulated Kinase Pathways (2000)

Activated neutrophils play an important role in the pathogenesis of sepsis, glomerulonephritis, acute renal failure, and other inflammatory processes. The resolution of neutrophil-induced inflammation relies, in large part, on removal of apoptotic neutrophils. Neutrophils are constitutively committed to apoptosis, but inflammatory mediators, such as GM-CSF, slow neutrophil apoptosis by incompletely understood mechanisms. We addressed the hypothesis that GM-CSF delays neutrophil apoptosis by activation of extracellular signal-regulated kinase (ERK) and phosphoinositide 3-kinase (PI 3-kinase) pathways. GM-CSF (20 ng/ml) significantly inhibited neutrophil apoptosis (GM-CSF, 32 vs 65% of cells p < 0. 0001). GM-CSF activated the PI 3-kinase/Akt pathway as determined by phosphorylation of Akt and BAD. GM-CSF-dependent Akt and BAD phosphorylation was blocked by the PI 3-kinase inhibitor LY294002. A role for the PI 3-kinase/Akt pathway in GM-CSF-stimulated delay of apoptosis was indicated by the ability of LY294002 to attenuate apoptosis delay. GM-CSF-dependent inhibition of apoptosis was significantly attenuated by PD98059, an ERK pathway inhibitor. LY294002 and PD98059 did not produce additive inhibition of apoptosis delay. To determine whether PI 3-kinase and ERK are used by other ligands that delay neutrophil apoptosis, we examined the role of these pathways in IL-8-induced apoptosis delay. LY294002 blocked IL-8-dependent Akt phosphorylation. PD98059 and LY294002 significantly attenuated IL-8 delay of apoptosis. These results indicate IL-8 and GM-CSF act, in part, to delay neutrophil apoptosis by stimulating PI 3-kinase and ERK-dependent pathways.
Distinguishing nonalcoholic steatohepatitis from fatty liver: serum‐free fatty acids, insulin resistance, and serum lipoproteins (2006)

Along with insulin resistance, serum LDL, and cholesterol-to-HDL ratio values increase with worsening severity of liver histology, and serum HDL values decline. Free fatty acids, however, do not vary between groups.
Use of plain copper conductors in lieu of tinned-copper for internal cables (1983)

Abstract : In line with most Telephone Operating Administrations, Telecom Australia has specified and used tinned-copper conductors, with PVC insulation and sheathing, for most internal cabling within telephone exchanges and subscribers' buildings. Following some reported problems associated with solderability, an investigation showed that the current production tinned conductors in Australia were inadequately specified; however, the excellent performance of plain copper prompted a more detailed investigation which revealed that plain copper conductors (i.e., no tinning) were suitable for all current applications of internal cable. The study covered soldering, wire wrapping, and insulation displacement terminations. As a result of this work, Telecom Australia has adopted plain copper as the standard for internal cables. This decision has resulted in both an improved performance in comparison with the previous tinned conductors (particularly in relation to solderability) and a substantial cable cost reduction. (Author)
Experimental Studies on the Facilitation of AV Conduction by Ectopic Beats in Dogs and Rabbits (1971)

Experiments were performed on the hearts of open-chest anesthetized dogs and on isolated rabbit hearts. Intracellular microelectrodes and bipolar surface electrodes were used for recording from and for stimulating the atria, AV node, bundle of His, bundle branches and ventricles. Atrial or ventricular premature beats which were usually blocked or delayed within the AV node were facilitated when ectopic activity caused preexcitation and early recovery of the site of block or delay. Ectopic atrial, ventricular, nodal, and bundle of His responses allowed previously blocked or delayed antegrade and retrograde beats to be conducted only when the ectopic activity arrived at an appropriate time at the site of block within the AV node. Therefore, apparent supernormal AV conduction may occur in the human heart by this mechanism, and some reported cases of supernormal conduction may be due to the preexcitation and early recovery of a refractory barrier by ectopic activity.
Novel oxygenation of pyridine and quinoline rings using acetyl hypofluorite (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel oxygenation of pyridine and quinoline rings using acetyl hypofluoriteShlomo Rozen, David Hebel, and Dov ZamirCite this: J. Am. Chem. Soc. 1987, 109, 12, 3789–3790Publication Date (Print):June 1, 1987Publication History Published online1 May 2002Published inissue 1 June 1987https://pubs.acs.org/doi/10.1021/ja00246a052https://doi.org/10.1021/ja00246a052research-articleACS PublicationsRequest reuse permissionsArticle Views859Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Effect of Some chemical and Biological Factors on the Degradation of Crude Oil at Sea, (1970)

This paper outlines some possible routes by which crude oil at sea may be degraded and describes some experiments designed to investigate three of these routes, namely, solubility and dispersion, consumption by zooplankton, and photochemical oxidation. (Author)
Dictionary Compression in Point Cloud Data Management (2017)

Nowadays, massive amounts of point cloud data can be collected thanks to advances in data acquisition and processing technologies like dense image matching and airborne LiDAR (Light Detection and Ranging) scanning. With the increase in volume and precision, point cloud data offers a useful source of information for natural resource management, urban planning, self-driving cars and more. At the same time, the scale at which point cloud data is produced, introduces management challenges: it is important to achieve efficiency both in terms of querying performance and space requirements. Traditional file-based solutions to point cloud management offer space efficiency, however, cannot scale to such massive data and provide the same declarative power as a database management system (DBMS).
A novel oscillating rectenna for wireless microwave power transmission (2002)

A new concept for solid state wireless microwave power transmission is presented. A 2.45 GHz rectenna element that was designed for over 85% RF to DC power conversion efficiency has been used to oscillate at 3.3 GHz with an approximate 1% DC to RF conversion efficiency. The RF radiation was obtained from the same circuit by supplying the DC output with reverse polarity DC power.
A 0.8V, sub-mW, varactor-tuning ring-oscillator-based clock generator in 32nm CMOS (2011)

A low-voltage operation, small-die-area, fully integrated Phase-Locked Loop (PLL) as a clock generator is described in an advanced 32nm CMOS technology. The PLL employs a fully digital, 6-bit automatic frequency calibrator (AFC), and varactors for frequency fine-tuning. To improve the performance and lower down the cost in mobile SoC applications, the PLL is capable of operating at a supply voltage of 0.8V over production test with only regular threshold voltage (RVT) transistors. The power consumption is measured at 0.7mW when a VCO oscillates at 700MHz frequency under a supply voltage of 0.8V. The total die size is 200μm by 200μm, including global power/ground routing, input ESD cells and on-chip power decoupling capacitors. Production tests show that the PLL consumes less than 0.7mW with a 0.8V supply and rms period jitter is less than 3.3ps at an output frequency of 700MHz.
Role of cytokines in psychopathology: Therapeutic implications (1998)

Cytokines can influence physiological functions such as sleep and food intake; they also interact with a number of neurotransmitters and second messengers in the brain. Cytokines are involved in a number of infectious, inflammatory, neoplastic, metabolic and degenerative illnesses. They also have been implicated in some psychiatric disorders, including 1) depressive and anxiety disorders; 2) schizophrenic disorders (chronic and acute); 3) autistic disorder; 4) eating disorders; and 5) obsessive-compulsive disorder. Alterations in cytokine peptide/receptor production or function in major psychiatric disorders are of special interest to researchers in the field. Exogenous administration of cytokines may be of therapeutic value in disorders in which the cytokine system may be disturbed. In some brain disorders of defined neuropathology, some cytokines have been found clinically useful. Such a development has yet to occur in the treatment of psychiatric disorders; however, some limited and very preliminary observations suggest that manipulation of the cytokine network may be of potential value in the treatment of some psychiatric disorders. Considering the human and economic costs of major psychiatric disorders, alteration of the cytokine network as a potential therapeutic tool is worthy of consideration and investigation.
Hierarchical PCE in GMPLS-based Multi-Domain Wavelength Switched Optical Networks (2011)

Hierarchical PCE is evaluated in GMPLS-based multi-domain WSONs. Simulations show that PCE providing edge nodes sequence using detailed information of inter-domain links achieves the best performance guaranteeing a lightweight control plane.
Effect of Branch Length on <sup>13</sup>C NMR Relaxation Properties in Molten Poly[ethylene‐<i>co</i>‐(<i>α</i>‐olefin)] Model Systems (2007)

Abstract The potential of branch length discrimination for branches containing six and more carbons via bulk NMR relaxation properties in the melt‐state has been explored. A systematic increase in the 13 C spin‐lattice relaxation time ( T ) of the terminal branch carbons 1 and 2 was observed when the branch increased from 6 to 16 carbons in length. The measurement of T via inversion recovery at high‐field showed the most reliable data. The effects of saturation and NOE were addressed by using recycle delays longer than 5 × T and the use of the saturation recovery was found to be unsatisfactory. All nuclear relaxation times were determined in a highly time efficient manner using a previously developed melt‐state MAS NMR method. magnified image
Portable Computer Keyboard For Use With One Hand (1992)

Data-entry device held in one hand and operated with five fingers. Contains seven keys. Letters, numbers, punctuation, and cursor commands keyed into computer by pressing keys in various combinations. Device called data egg used where standard typewriter keyboard unusable or unavailable. Contains micro-processor and 32-Kbyte memory. Captures text and transmits it to computer. Concept extended to computer mouse. Especially useful to handicapped or bedridden people who find it difficult or impossible to operate standard keyboards.
Experimental Investigation of Inertial Mixing in Colliding Droplets (2012)

Achieving the increasingly fast mixing requirements posed by the chemical, biological, and life science community for confined microchannel droplet flows remains an engineering challenge. The viscous and surface tension forces that often dominate microflows undermine fast, efficient mixing. A novel mixing arrangement based on droplet collisions has been developed that significantly improves mixing rates by utilizing inertia to rapidly rearrange fluid contents. This article experimentally investigates inertial droplet mixing in micro-flows following high-speed droplet pair collisions. The technique utilizes a gaseous flow for liquid droplet generation and transport with collisions occurring in Y-junction microchannel geometries. Mixing rates are quantified using differential fluorescent optical diagnostics, custom image processing algorithms, and statistical analysis. Measured droplet mixing times are compared to the characteristic time scales for mass and viscous diffusion and bulk convective transport. Results show that mixing times are decreased as the droplet pair collision inertia is increased, indicating the potential benefit for inertial collision mixing.
Detection by Counterimmunoelectrophoresis of Anti-Candida Precipitins in Sera from Cancer Patients (1979)

Five antigen preparations from yeast-phase cells and hyphalphase cells of Candida albicans were used to detect antibodies in sera from cancer patients by use of counterimmunoelectrophoresis (CIE). Sera from uninfected patients, patients with superficial infections, and patients who had invasive or systemic candidiasis were analyzed for antibodies. A high incidence (27%) of false-negative data was obtained for patients who had systemic candidiasis. Serum titers of all patient groups were below 1:10. Of the antigens tested, cytoplasmic antigen from yeast-phase cells provided the greatest sensitivity and diagnostic value.
Toll-Like Receptor Stimulation by MicroRNAs in Acute Graft-vs.-Host Disease (2018)

Acute graft-vs.-host disease (aGVHD) is a frequent complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), accounting for substantial morbidity and mortality associated with this treatment modality. The pathogenesis of aGVHD involves a complex cascade of humoral and cellular interactions in which donor T cells target HLA mismatched host tissues, causing tissue injury through secretion of pro-inflammatory cytokines and induction of direct cytotoxicity. Toll-like receptors (TLRs) are key components of the innate immune system that recognize endogenous danger-associated molecular patterns (DAMPs) and exogenous pathogen-associated molecular patterns (PAMPs). Patients receiving conditioning chemotherapy and/or whole-body irradiation prior to all-HSCT are prone to gastrointestinal damage and translocation of microbiota across compromised intestinal epithelium, resulting in release of PAMPs and DAMPs. These "danger signals" play critical roles in disease pathogenesis by both initiating and propagating aGVHD through dendritic cell maturation and alloreactive T cell responses. There are 10-15 TLRs identified in mammalian species, a subset of which recognize single-stranded RNA (ssRNA) and serve as a key component of viral immunity. Recently, ssRNAs other than those of viral origin have been investigated as potential ligands of TLRs. MicroRNAs (miRs) are short (19-24 nt) non-coding RNAs that play critical roles in a variety of diseases. While traditionally miRs post-translationally modulate gene expression, non-canonical functions such as regulating TLR stimulation by acting as TLR ligands have been described. Here, we review the role of TLRs in aGVHD pathogenesis, the function of miRs in TLR stimulation, and the recent literature describing miRs as TLR ligands in aGVHD.
Molecular and Cellular Physiology of Apolipoprotein A-I Lipidation by the ATP-binding Cassette Transporter A1 (ABCA1) (2004)

The dynamics of ABCA1-mediated apoA-I lipidation were investigated in intact human fibroblasts induced with 22(R)-hydroxycholesterol and 9-cis-retinoic acid (stimulated cells). Specific binding parameters of (125)I-apoA-I to ABCA1 at 37 degrees C were determined: K(d) = 0.65 microg/ml, B(max) = 0.10 ng/microg cell protein. Lipid-free apoA-I inhibited the binding of (125)I-apoA-I to ABCA1 more efficiently than pre-beta(1)-LpA-I, reconstituted HDL particles r(LpA-I), or HDL(3) (IC(50) = 0.35 +/- 1.14, apoA-I; 1.69 +/- 1.07, pre-beta(1)-LpA-I; 17.91 +/- 1.39, r(LpA-I); and 48.15 +/- 1.72 microg/ml, HDL(3)). Treatment of intact cells with either phosphatidylcholine-specific phospholipase C or sphingomyelinase affected neither (125)I-apoA-I binding nor (125)I-apoA-I/ABCA1 cross-linking. We next investigated the dynamics of apoA-I lipidation by monitoring the kinetic of apoA-I dissociation from ABCA1. The dissociation of (125)I-apoA-I from normal cells at 37 degrees C was rapid (t((1/2)) = 1.4 +/- 0.66 h; n = 3) but almost completely inhibited at either 15 or 4 degrees C. A time course analysis of apoA-I-containing particles released during the dissociation period showed nascent apoA-I-phospholipid complexes that exhibited alpha-electrophoretic mobility with a particle size ranging from 9 to 20 nm (designated alpha-LpA-I-like particles), whereas lipid-free apoA-I incubated with ABCA1 mutant (Q597R) cells was unable to form such particles. These results demonstrate that: 1) the physical interaction of apoA-I with ABCA1 does not depend on membrane phosphatidylcholine or sphingomyelin; 2) the association of apoA-I with lipids reduces its ability to interact with ABCA1; and 3) the lipid translocase activity of ABCA1 generates alpha-LpA-I-like particles. This process plays in vivo a key role in HDL biogenesis.
Identification of Enterotoxigenic <i>Escherichia coli</i> and Serum Antitoxin Activity by the Vascular Permeability Factor Assay (1973)

Twenty-five strains of enterotoxigenic (tox(+)) Escherichia coli isolated in India, Bangladesh, and the U.S.A. were shown to produce vascular permeability factor (PF) activity as well as diarrheagenic activity. Sixteen strains of non-enterotoxigenic E. coli were found to be PF negative. The PF response elicited by tox(+)E. coli isolated in the U.S.A. from cases of infantile diarrhea was qualitatively different and more difficult to demonstrate. However, this problem was surmounted by assaying 25-fold concentrates of the crude enterotoxin of these strains. PF activity of various strains of tox(+)E. coli was neutralized by anti-PF antiserum prepared against the enterotoxin of strain H-10407. This anti-PF antiserum also neutralized PF activity of Vibrio cholerae enterotoxin (choleragen). Antiserum containing antibody specific for purified choleragen neutralized E. coli PF activity. These and other results indicate that the PF activity of E. coli is a function of the diarrheagenic enterotoxin as is known to be the case with choleragen. We conclude that the PF assay can be employed for the identification of tox(+)E. coli and for the detection of antitoxic antibody.
La preparación física en la formación de jugadores de deportes de equipo (2005)

?Que papel ocupa la preparacion fisica en la formacion de deportistas de equipo? ?Es realmente un factor relevante para el futuro del jugador? ?Es necesario planificarla? Pretendemos dar respuesta a estas y otras cuestiones relacionadas con el entrenamiento condicional en las etapas formativas. La preparacion fisica en la formacion se descuida a menudo por diferentes razones: la ignorancia y/o la busqueda de resultados inmediatos son, en general, el origen de este descuido. Explicaremos los perjuicios que puede acarrear esto y, por el contrario, los enormes beneficios que conlleva una planificacion deportiva que integre la preparacion fisica como aspecto fundamental en la formacion. Igualmente, expondremos las caracteristicas del entrenamiento de las diferentes capacidades fisicas teniendo en cuenta todos los factores relevantes para el mismo: momento en el desarrollo del jugador, caracteristicas del crecimiento, las fases sensibles de las diferentes capacidades,...