gebhart/patrepeval huggingface dataset:
Peripheral Nerve Findings in Rett Syndrome (1988)

Sural nerve and peroneus brevis muscle biopsies were studied in 12 patients with Rett syndrome, ten with the typical form of the disorder according to 1985 criteria, and two with atypical features. Ages ranged from 23 months to 25 years. All stages of the disease were represented. There was evidence of a mild axonal neuropathy in seven of 12 patients. Degenerative and occasional regenerative changes were seen in five sural nerve biopsies, including one from the youngest patient in the series, who was normally nourished and fully ambulatory. Occasional nonspecific ultrastructural abnormalities were present, including accumulation of pi granules in Schwann cells and Hirano bodies within axons. However, morphometric analysis of the four nerves in which these alterations were most prominent showed a normal density and size distribution of myelinated fibers. Enzyme histochemistry of the peroneus brevis biopsies demonstrated abnormal predominance of type II muscle fibers in three of the 12 biopsies and atrophy of type I fibers in one patient.
The enzyme-activated irreversible inhibition of type-B monoamine oxidase by 3-{4-[(3-chlorophenyl)methoxy]phenyl}-5-[(methylamino) methyl]-2-oxazolidinone methanesulphonate (compound MD 780236) and the enzyme-catalysed oxidation of this compound as competing reactions (1983)

3-(4-[(3-Chlorophenyl)methoxy]phenyl)-5-[(methylamino)methyl]-2- oxazolidinone methanesulphonate (compound MD 780236) is a selective inhibitor of the B-form of monoamine oxidase. Inhibition involves an initial non-covalent interaction between enzyme and inhibitor followed by a time-dependent process resulting in irreversible inhibition. The initial, reversible, phase of inhibition was found to be competitive with respect to phenethylamine and 5-hydroxytryptamine, and a comparison of the Ki values indicated the affinity of the inhibitor for the B-form of the enzyme to be some 7-fold greater than its affinity for the A-form. This selectivity was considerably enhanced by preincubation of the enzyme and inhibitor. Time courses showed that complete inhibition was not achieved under conditions where the inhibitor concentration was over 100-fold greater than that of the enzyme. Assay of the activity of monoamine oxidase by determining the release of hydrogen peroxide fluorometrically showed compound MD 780236 to be a substrate for, as well as an inhibitor of, monoamine oxidase, and kinetic analysis revealed that the rate of product formation was some 530-fold greater than that of the process leading to irreversible inhibition of the B-form of the enzyme.
Automatic keyphrase extraction and ontology mining for content-based tag recommendation (2010)

Collaborative tagging represents for the Web a potential way for organizing and sharing information and for heightening the capabilities of existing search engines. However, because of the lack of automatic methodologies for generating the tags and supporting the tagging activity, many resources on the Web are deficient in tag information, and recommending opportune tags is both a current open issue and an exciting challenge. This paper approaches the problem by applying a combined set of techniques and tools (that uses tags, domain ontologies, keyphrase extraction methods) thereby generating tags automatically. The proposed approach is implemented in the PIRATES (Personalized Intelligent tag Recommender and Annotator TEStbed) framework, a prototype system for personalized content retrieval, annotation, and classification. A case study application is developed using a domain ontology for software engineering. © 2010 Wiley Periodicals, Inc.
AdHapticA: Adaptive Haptic Application Framework (2008)

Research performed in the area of haptics has produced some remarkable results with a variety of haptic devices. However, haptic-based applications are designed to consider only a particular haptic device. Therefore, the functionality of a haptic-based system is limited by the chosen device's features, such as workspace, device's inertia, friction, number of points of interaction, number of degrees of freedom, and maximum force that can be exerted. In short, these haptic-based systems are limited for use with a certain haptic device. Without a doubt, the need for a software tool to adapt existing haptic-based systems to the capabilities of another haptic device is evident. On the other hand, one of the main advantages of using haptic devices is the possibility of saving data during the haptic interaction. Our proposed framework, which is called Adaptive Haptic Application (AdHapticA), deals with both issues: It automatically adapts a haptic-based system to be used with another haptic device and saves the corresponding haptic data for quantitative evaluation. The AdHapticA framework can be used to study the feasibility of certain haptic devices to meet the requirements of an application. A case study is presented to evaluate single-point interaction and hand exoskeleton haptic devices for authentication purposes by using the same virtual scenario. The applicability of the proposed framework is shown, and the results obtained from the haptic data are captured when a particular application is performed with either single-point (desktop device) or multipoint interaction devices (hand exoskeleton). Therefore, the results have shown that current hand exoskeleton devices are less suitable for tasks that require a certain level of precision, like haptic-biometric-based tasks.
Self-Consistent Analysis of Strain-Compensated InGaN–AlGaN Quantum Wells for Lasers and Light-Emitting Diodes (2008)

Strain-compensated InGaN-AlGaN quantum wells (QW) are investigated as improved active regions for lasers and light emitting diodes. The strain-compensated QW structure consists of thin tensile-strained AlGaN barriers surrounding the InGaN QW. The band structure was calculated by using a self-consistent 6-band <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">k</i> middot <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p</i> formalism, taking into account valence band mixing, strain effect, spontaneous and piezoelectric polarizations, as well as the carrier screening effect. The spontaneous emission and gain properties were analyzed for strain-compensated InGaN-AlGaN QW structures with indium contents of 28%, 22%, and 15% for lasers (light-emitting diodes) emitting at 480 (500), 440 (450), and 405 nm (415 nm) spectral regimes, respectively. The spontaneous emission spectra show significant improvement of the radiative emission for strain-compensated QW for all three structures compared to the corresponding conventional InGaN QW, which indicates the enhanced radiative efficiency for light emitting diodes. Our studies show the improvement of the optical gain and reduction of the threshold current density from the use of strain-compensated InGaN-AlGaN QW as active regions for diode lasers.
Strontium 89 Therapy for the Palliation of Pain Due to Osseous Metastases (1995)

As many as 80% of selected patients with painful osteoblastic bony metastases from prostate or breast cancer may experience some pain relief following 89Sr administration. In addition, as many as 10% or more may become pain free. Duration of clinical response may average 3 to 6 months in some cases. Hemotoxicity is mild. A decrease in treatment costs with administration of 89Sr to patients with painful osteoblastic bony metastases from prostate cancer may occur. These observations reflect the preliminary nature of knowledge in this field and point to the need for larger clinical trials of the use of 89Sr palliation.
2,3,7,8,12,13,17,18-Octakis(.beta.-hydroxyethyl)porphyrin (octaethanolporphyrin) and its liquid crystalline derivatives: synthesis and characterization (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT2,3,7,8,12,13,17,18-Octakis(.beta.-hydroxyethyl)porphyrin (octaethanolporphyrin) and its liquid crystalline derivatives: synthesis and characterizationBrian A. Gregg, Marye Anne Fox, and Allen J. BardCite this: J. Am. Chem. Soc. 1989, 111, 8, 3024–3029Publication Date (Print):April 1, 1989Publication History Published online1 May 2002Published inissue 1 April 1989https://pubs.acs.org/doi/10.1021/ja00190a041https://doi.org/10.1021/ja00190a041research-articleACS PublicationsRequest reuse permissionsArticle Views562Altmetric-Citations154LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Deleterious Effects of Prolonged Electrical Excitation of Striate Cortex in Macaques (1977)

Macaques were trained to respond to electrical excitation applied through electrodes permanently implanted within or upon striate cortex. Threshold current for the animal to detect this stimulation was highly consistent from day to day and, in the absence of tissue encapsulation of the electrodes or deliberately inflicted damage, remained stable indefinitely, 38 months in the longest case so far. Stimulating continuously for 1-8h, however, produces an elevation of threshold, which may be permanent or temporary, depending upon a variety of conditions. A major cause of such injury is the hydrolysis commonly occurring consequent to passage of low-level currents between solutions and metal electrodes. Even when the hydrolytic reaction is eliminated by restricting the level of electrode polarization or by using capacitative stimulation with tantalum pentoxide electrodes, a rise in threshold often still occurs with protracted stimulation. With proper control in some instances, however, effective stimulation at 2-10 times the threshold level could be maintained indefinitely without apparent injury, e.g. in a blind monkey having a threshold of 290 muA that could respond immediately to an 80-muA diminution in 580-muA, 0.2-msec stimulus pulses which had been applied steadily for 1 h at 50 Hz.
Direct osmylation of benzenoid hydrocarbons. Charge-transfer photochemistry of osmium tetraoxide (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDirect osmylation of benzenoid hydrocarbons. Charge-transfer photochemistry of osmium tetraoxideJ. M. Wallis and Jay K. KochiCite this: J. Org. Chem. 1988, 53, 8, 1679–1686Publication Date (Print):April 1, 1988Publication History Published online1 May 2002Published inissue 1 April 1988https://pubs.acs.org/doi/10.1021/jo00243a015https://doi.org/10.1021/jo00243a015research-articleACS PublicationsRequest reuse permissionsArticle Views248Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Oxidative coupling of methane over the oxides of Group IIIA, IVA, and VA metals (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidative coupling of methane over the oxides of Group IIIA, IVA, and VA metalsI. T. Ali Emesh and Y. AmenomiyaCite this: J. Phys. Chem. 1986, 90, 20, 4785–4789Publication Date (Print):September 1, 1986Publication History Published online1 May 2002Published inissue 1 September 1986https://pubs.acs.org/doi/10.1021/j100411a015https://doi.org/10.1021/j100411a015research-articleACS PublicationsRequest reuse permissionsArticle Views324Altmetric-Citations77LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Clinical trial: an efficacy evaluation of reduced bisacodyl given as part of a polyethylene glycol electrolyte solution preparation prior to colonoscopy (2007)

Two-litre sulphate-free electrolyte lavage method solution with 10-mg bisacodyl is as effective as the 20-mg bisacodyl preparation for cleansing the colon prior to colonoscopy. The 10-mg bisacodyl regimen has an improved safety profile, with significantly reduced cramping, nausea and overall discomfort.
Liquid-Liquid Phase Separation in Alkali Metal-Ammonia Solutions. I. Lithium, Potassium, Rubidium, with New Data on Sodium (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLiquid-Liquid Phase Separation in Alkali Metal-Ammonia Solutions. I. Lithium, Potassium, Rubidium, with New Data on SodiumPaul D. Schettler Jr. and Andrew Patterson Jr.Cite this: J. Phys. Chem. 1964, 68, 10, 2865–2869Publication Date (Print):October 1, 1964Publication History Published online1 May 2002Published inissue 1 October 1964https://pubs.acs.org/doi/10.1021/j100792a020https://doi.org/10.1021/j100792a020research-articleACS PublicationsRequest reuse permissionsArticle Views138Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Structure and Lithium Extraction Mechanism in LiNi0.5Mn1.5O4 after Double Substitution with Iron and Titanium (2006)

The simultaneous partial replacement of Ni and Mn by Fe and Ti in the 5-V spinel was studied. The spinel structure is preserved after double substitution of iron and titanium, while partial tetrahedral site occupancy by iron ions was observed. The best capacity retention in lithium cells was achieved by double substitution for the composition, associated with the particular single-phase mechanism of lithium extraction combined with the structural stabilization induced by titanium and tetrahedral iron. In addition, the capacity is higher for smaller particle sizes, while a slightly higher capacity retention is found for larger, regularly shaped particles.
Monitoring and Visualizing Program Execution: an Exploratory Approach (1996)

Contents I Fundamental Concepts 11 1 Introduction 13 1.2 Types of program understanding tools : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 14 15 1.4 Contributions : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 16 1.5 Overview of this book : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 17 2 Related Work 19 2.1 Information sources and access methods : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 19 2.2 Execution Models : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 20 20 2.4 Run-time instrumentation systems : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 21 21 2.4.2 Dalek : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 22 2.4.3 Parasight : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : 22 22 2.5 Manual instrumentation systems : : : : : :
Free Energy Determinants of Secondary Structure Formation: I. α-Helices (1995)

The Zimm-Bragg parameters s and sigma are calculated for the helix-coil transition of poly-L-alanine. The theoretical approach involves evaluating gas phase conformational energies for both coil and helical states using the CHARMM potential function and accounting for solvation effects with various continuum solvation models. Conformational free energies are then incorporated into a formalism developed by Go et al. for the calculation of s and sigma. Calculated values for both s and sigma as well as the enthalpy change associated with helix formation are in good agreement with experimental data when the Finite Difference Poisson-Boltzmann (FDPB) method is used to treat solvent effects. The driving force for the helix-coil transition is analyzed in terms of individual free energy components. Hydrogen bond formation is found to contribute little to helix stability because the internal hydrogen bonding energy is largely canceled by the large free energy cost associated with removing polar groups from water. The entropic cost associated with fixing backbone dihedral angles in the helical conformation is found to be approximately 7 e.u./residue (about 2 kcal/mol at room temperature). The major driving force favoring helix formation can be associated with interactions including enhanced van der Waals interactions in the close-packed helix conformation and the hydrophobic effect. These contribute about 2 kcal/mol favoring the helical state. The differences in helical propensities between alanine and glycine are attributed primarily to hydrophobic and packing interactions involving the C beta with a smaller contribution arising from increased conformational freedom for glycine in the coil state. The description of helix formation presented here is consistent with previous conclusions regarding tertiary structure formation which suggest that hydrophobic and close-packed interactions provide stability while hydrogen bond formation constitutes a structural constraint imposed by the high free energy cost associated with burying unsatisfied hydrogen bonding groups. alpha-Helix formation may thus be viewed as a form of hydrophobic collapse constrained by the requirement that polar groups be either exposed to solvent or form hydrogen bonds. More generally it appears from this study that for a folding model to be a realistic, it must properly account for the chemical nature of the polypeptide chain, particularly the solvation energetics of amide groups.
The clinical efficacy of Rev-Eyes in reversing the effects of pupillary dilation. (1993)

Our data suggest limited utility for Rev-Eyes with a young population. The recovery rate of near visual acuity and amplitude of accommodation is identical with or without Rev-Eyes.
Anionic polymerization of primary acrylates as promoted by lithium 2‐(2‐methoxyethoxy) ethoxide (1997)

Some primary acrylates, such as methyl, ethyl, n-butyl, and n-nonyl acrylate (MA, EA, nBuA and nNonA, respectively) have been anionically polymerized by using diphenylmethyl lithium (DPMLi) as an initiator, in the presence of a chelating μ-σ dual ligand, i.e., a polydentate lithium alkoxide, at low temperature. It has been found that lithium 2-(2-methoxyethoxy) ethoxide (LiOEEM) is a very efficient ligand in preventing the anionic polymerization of these monomers from being disturbed by significant secondary transfer and termination reactions. Even for the difficult cases of ethyl and methylacrylate, that approach provides high polymerization yields and low polydispersity, allowing the molecular weight to be predetermined. LiOEEM/initiator molar ratio, solvent polarity, temperature and monomer concentration have proved to be key parameters in the control of the polymerization process. The efficiency of that control is however dependent on the monomer structure and improves with the length of the n-alkyl substituent, i.e., MA < EA < nBuA < nNonA. © 1997 John Wiley & Sons, Inc.
Incremental query evaluation in a ring of databases (2010)

This paper approaches the incremental view maintenance problem from an algebraic perspective. We construct a ring of databases and use it as the foundation of the design of a query calculus that allows to express powerful aggregate queries. The query calculus inherits key properties of the ring, such as having a normal form of polynomials and being closed under computing inverses and delta queries. The k-th delta of a polynomial query of degree k without nesting is purely a function of the update, not of the database. This gives rise to a method of eliminating expensive query operators such as joins from programs that perform incremental view maintenance. The main result is that, for non-nested queries, each individual aggregate value can be incrementally maintained using a constant amount of work. This is not possible for nonincremental evaluation.
Improved Health-related Quality of Life and Physical Function in Patients with Refractory Chronic Gout Following Treatment with Pegloticase: Evidence from Phase III Randomized Controlled Trials (2012)

Pegloticase therapy resulted in statistically significant and clinically meaningful improvements in PtGA, pain, physical function, and HRQOL.
Quantitative evaluation on [⁹⁰Y] DOTATOC PET and SPECT imaging by phantom acquisitions and clinical applications in locoregional and systemic treatments. (2012)

[⁹⁰Y]-activity quantification is feasible by SPECT and PET imaging. For clinical applications, SPECT-CT is the best technique for visualizing the radiopharmaceuticals following systemic infusion, while both SPECT and PET scans are effective in analyzing locoregional distribution. Nevertheless PET study demonstrates the best spatial definition.
Addendum to a paper on method-comparison analysis. (1983)

Journal Article Addendum to a paper on method-comparison analysis. Get access I A Naus I A Naus Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 29, Issue 9, 1 September 1983, Pages 1697–1698, https://doi.org/10.1093/clinchem/29.9.1697a Published: 01 September 1983