gebhart/patrepeval huggingface dataset:
Conversion of Tertiary Phosphites to Secondary Phosphonates. Diphenyl Phosphonate<sup>1</sup> (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConversion of Tertiary Phosphites to Secondary Phosphonates. Diphenyl Phosphonate1E. N. WalshCite this: J. Am. Chem. Soc. 1959, 81, 12, 3023–3026Publication Date (Print):June 1, 1959Publication History Published online1 May 2002Published inissue 1 June 1959https://pubs.acs.org/doi/10.1021/ja01521a028https://doi.org/10.1021/ja01521a028research-articleACS PublicationsRequest reuse permissionsArticle Views1197Altmetric-Citations77LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Secure two-party k-means clustering (2007)

The k-Means Clustering problem is one of the most-explored problems in data mining to date. With the advent of protocols that have proven to be successful in performing single database clustering, the focus has shifted in recent years to the question of how to extend the single database protocols to a multiple database setting. To date there have been numerous attempts to create specific multiparty k-means clustering protocols that protect the privacy of each database, but according to the standard cryptographic definitions of "privacy-protection," so far all such attempts have fallen short of providing adequate privacy.
Millimeter-wave carrier generation using an optical phase modulator and an optical notch filter (2004)

The effective bandwidth of a wireless communication system is proportional to the carrier frequency, shifting the operating frequency of the wireless system from the crowded microwave L and S bands to the unregulated mm-wave band is a trend for future broadband wireless services. Intensity modulation and direct detection scheme (IM/DD) has been considered a simple method to impose a millimeter-wave signal onto optical fiber. However, for systems using IM/DD, the chromatic dispersion introduce significant power penalty, which limits the transmission distance. Remote heterodyne schemes have been proposed to solve the dispersion problem. Several approaches have been proposed to generate two phase-correlated optical wavelengths that are separated at a required millimeter-wave frequency. These approaches include single-side band with carrier modulation, optical carrier-suppressed modulation, optical offset injection locking and optical offset phase locking of two laser sources. All these methods provides phase-correlated optical wavelengths, but with complicated system configuration and high system cost. In this paper, we propose a simple method to generate phase-correlated wavelengths using a phase modulator and two fiber Bragg gratings. Two wavelengths are generated by modulating the phase modulator with an RF frequency. The required millimeter-wave signal is obtained by selecting two sidebands using the two narrowband fiber Bragg gratings. Theoretical analysis and experimental results will be reported in the paper.
Electrochemical machining of 20MnCr5 alloy steel with ferric nitrate mixed aqueous NaCl electrolyte (2015)

Electrochemical machining (ECM) is a fast growing and widely used advanced machining process. Improving a material removal rate (MRR) of ECM is still a topic of concern in order to utilise its full potential. In this paper, ferric nitrate (FeNO3) was included in small proportions in the aqueous NaCl electrolyte solution in the direction of improving ECM performance. The performance parameters i.e. MRR and surface roughness (Ra) have been greatly improved by enhancing the ionisation of the electrolyte by this new mixture of electrolyte. It was found that FeNO3 has suitable characteristics to mix with NaCl to enhance the ionisation reaction. In this work, experimental investigation was conducted to study the electrochemical machining characteristics of 20MnCr5 alloy steel for both aqueous NaCl and FeNO3 mixed aqueous NaCl electrolytes. The significance of ECM process parameters such as flow rate of electrolyte, tool feed rate, voltage and current on MRR and Ra was analysed. Microstructure of surface of the specimen machined with FeNO3 mixed aqueous NaCl electrolyte shows the improvement in surface finish.
Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms (2006)

Overexpression of the amyloid precursor protein (APP) in hippocampal neurons leads to elevated beta-amyloid peptide (Abeta) production and consequent depression of excitatory transmission. The precise mechanisms underlying APP-induced synaptic depression are poorly understood. Uncovering these mechanisms could provide insight into how neuronal function is compromised before cell death during the early stages of Alzheimer's disease. Here we verify that APP up-regulation leads to depression of transmission in cultured hippocampal autapses; and we perform whole-cell recording, FM imaging, and immunocytochemistry to identify the specific mechanisms accounting for this depression. We find that APP overexpression leads to postsynaptic silencing through a selective reduction of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor-mediated currents. This effect is likely mediated by Abeta because expression of mutant APP incapable of producing Abeta did not depress transmission. In addition, although we eliminate presynaptic silencing as a mechanism underlying APP-mediated inhibition of transmission, we did observe an Abeta-induced presynaptic deficit in vesicle recycling with sustained stimulation. These findings demonstrate that APP elevation disrupts both presynaptic and postsynaptic compartments.
Experimental researches in electricity: Twenty-ninth series (1854)

Abstract In the present series of researches the author endeavours in the first place to establish the principles he announced in the last, with regard to the definite character of the lines of magnetic force, by results obtained experimentally with the magnetic force of the earth. For this purpose he reverts to the thick wire galvanometer before described, and points out the precautions respecting the cleanliness of the coils, the thickness and shortness of the conductors, the perfect contacts, effected either by soldering or cups of mercury; and marks the value of double observations, i. e. observations afforded on both sides of zero.
Fragmentations induced by ion-atom reactions (1997)

Fragmentation of electron-impact-generated organic molecular cations, submitted to low-energy collisions with hydrogen in a MS/MS/MS multiquadrupole mass spectrometer, was promoted or significantly increased in the presence of atomic hydrogen generated from a microwave discharge. Loss of hydrogen alpha to a heteroatom and bond cleavage alpha to a carbonyl group are the major H-induced fragmentation pathways.
Heparin cofactor II. Purification and properties of a heparin-dependent inhibitor of thrombin in human plasma. (1982)

We have isolated a previously unrecognized heparin-dependent inhibitor of thrombin from human plasma. The inhibitor, designated heparin cofactor II (HCII), was purified to homogeneity with sulfated-dextran, DEAE-Sepharose, heparin-Sepharose and Sephadex G-150. HCII is a glycoprotein consisting of a single polypeptide chain with a Mr = 65,600 as determined by sedimentation equilibrium analysis. Other physical properties include s20,w = 4.31 S; Stokes radius = 34 A; E280 1% = 11.7; and pI = 4.95 to 5.15. The purified inhibitor is not precipitated by antibodies directed against seven other plasma protease inhibitors, including antithrombin III (ATIII). HCII blocks the proteolytic and amidolytic activities of thrombin by forming a covalent, 1:1 molar complex with the protease. The second-order rate constant for inhibition of thrombin by purified HCII increases from 5.0 X 10(5) M-1 min-1 in the absence of heparin to 4.5 x 10(8) M-1 min-1 at optimal heparin concentrations of 0.8 to 1.0 unit/ml. In comparison with ATIII, HCII is a relatively ineffective inhibitor of coagulation factor Xa.
Spatial Differentiation by a Lateral Shear Interferometer (1972)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text S. Mallick, M. Françon, and A. Sáez, "Spatial Differentiation by a Lateral Shear Interferometer," Appl. Opt. 11, 479-480 (1972) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Use of Dispersive Delay Lines for Signal Processing in Underwater Acoustics (1969)

Signal processors incorporating dispersive delay lines can be designed for matched filters in active sonars, for spectrum analyzers in passive listening, and for generators of frequency-modulated codes. Depending upon its bandwidth and its duration, the signal to be processed is fed into a dispersive delay line that is matched to it in the case of wide-band systems, or matched to an homothetic signal (a signal having the same modulation characteristics, the same time-bandwidth product as the original signal, but having a frequency scale multiplied or divided by a factor k and a time scale divided or multiplied by the same factor k) with a larger bandwidth in the case of narrow-band systems. In this last case, the signal is previously time compressed with an appropriate unit, such as a recirculating memory or a magnetic recorder.
Persistent, triple-virus co-infections in mosquito cells (2010)

Individual mosquito cells can accommodate at least 3 viruses simultaneously in an adaptive manner. The phenomenon provides an opportunity for genetic exchange between diverse viruses and it may have important medical and veterinary implications for arboviruses.
Differential Requirements for Survivin in Hematopoietic Cell Development. (2004)

Abstract The development of the complete repertoire of blood cells from a common progenitor, the hematopoietic stem cell, is a tightly controlled process that is regulated, in part, by the activity of lineage specific transcription factors. Despite our knowledge of these factors, the mechanisms that regulate the formation and growth of distinct, but closely related lineages, such as erythroid cells and megakaryocytes, remain largely uncharacterized. Here we show that Survivin, a member of the inhibitor of apoptosis (IAP) family that also plays an essential role in cytokinesis, is differentially expressed during erythroid versus megakaryocyte development. Erythroid cells express Survivin throughout their maturation, up to the terminal stage of differentiation (orthochromatic), even after the cells exit the cell cycle. This is surprising because Survivin is generally expressed in a cell cycle dependent manner and not thought to be expressed in terminally differentiated cells. In contrast, purified murine megakaryocytes express nearly 5-fold lower levels of Survivin mRNA compared to erythroid cells. To investigate whether Survivin is involved in the differentiation and/or survival of hematopoietic progenitors, we infected primary mouse bone marrow cells with retroviruses harboring either the human Survivin cDNA or a mouse Survivin shRNA, and then induced erythroid and megakaryocyte differentiation in both liquid culture and colony-forming assays. These studies revealed that overexpression of Survivin promoted the terminal differentiation of red blood cells, while its reduction, by RNA interference, inhibited their differentiation. In contrast, downregulation of Survivin facilitated the expansion of megakaryocytes, and its overexpression antagonized megakaryocyte formation. In addition, consistent with a role for survivin in erythropoiesis, downregulation of Survivin expression in MEL cells led to a block in terminal differentiation. Finally, since caspase activity is known to be required for erythroid maturation, we investigated whether survivin associated with cleaved caspase-3 in erythroid cells. Immunofluorescence revealed that Survivin and cleaved caspase-3 co-localized to discrete foci within the cytoplasm of erythroid cells at the orthochromatic stage of development. Based on these findings, we hypothesize that Survivin cooperates with cleaved caspase-3 in terminal maturation of red blood cells. Together, our findings demonstrate that Survivin plays multiple, distinct roles in hematopoiesis.
Hypoxic conditioned culture medium from fibroblasts grown under embryonic‐like conditions supports healing following post‐laser resurfacing (2009)

This HCCM product may have broad applications within the field of skin wound repair.
Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia (2012)

These studies support a role for Ces1/Es-x in the partitioning of regulatory fatty acids and concomitant control of hepatic lipid biosynthesis, secretion, and deposition.
Complex Chemical Equilibrium Calculations (1970)

Comparison of chemical equilibrium formulations and thermodynamic derivative computations for gases
Social network data management (2011)

With the increasing usage of online social networks and the semantic web's graph structured RDF framework, and the rising adoption of networks in various fields from biology to social science, there is a rapidly growing need for indexing, querying, and analyzing massive graph structured data. Facebook has amassed over 500 million users creating huge volumes of highly connected data. Governments have made RDF datasets containing billions of triples available to the public. In the life sciences, researches have started to connect disparate data sets of research results into one giant network of valuable information. Clearly, networks are becoming increasingly popular and growing rapidly in size, requiring scalable solutions for network data management. 
This thesis focuses on the following aspects of network data management. We present a hierarchical index structure for external memory storage of network data that aims to maximize data locality. We propose efficient algorithms to answer subgraph matching queries against network databases and discuss effective pruning strategies to improve performance. We show how adaptive cost models can speed up subgraph matching query answering by assigning budgets to index retrieval operations and adjusting the query plan while executing. 
We develop a cloud oriented social network database, COSI, which handles massive network datasets too large for a single computer by partitioning the data across multiple machines and achieving high performance query answering through asynchronous parallelization and cluster-aware heuristics. 
Tracking multiple standing queries against a social network database is much faster with our novel multi-view maintenance algorithm, which exploits common substructures between queries. 
To capture uncertainty inherent in social network querying, we define probabilistic subgraph matching queries over deterministic graph data and propose algorithms to answer them efficiently. 
Finally, we introduce a general relational machine learning framework and rule-based language, Probabilistic Soft Logic, to learn from and probabilistically reason about social network data and describe applications to information integration and information fusion.
CSF‐suppressed quantitative single‐shot diffusion imaging (1991)

Abstract A CSF‐suppressed, inversion‐recovery (IR) single‐shot diffusion sequence was used to demonstrate that CSF makes a dominant contribution to the nonmonoexponential diffusion decay behavior observed in cortical gray matter brain tissue. © 1991 Academic Press, Inc.
Rol, perfil y espacio profesional del Trabajo Social en el ámbito educativo (2012)

espanolEste trabajo muestra el rol, perfil y espacio profesional de los/as Trabajadores/as Sociales en el area educacion, especificamente en liceos y escuelas municipalizadas de cinco comunas de la provincia de Nuble, Octava Region del Bio-Bio. Como resultados y conclusiones se destaca la multiplicidad de roles que desempenan los/as Trabajadores/as Sociales en el ambito educativo, y que el espacio profesional en esta area es amplio y diverso. Tambien se releva la labor que realizan estos/as profesionales a nivel familiar y el apoyo que podrian facilitar en la elaboracion e implementacion de los Proyectos Educativos Institucionales. El perfil profesional de los/as Trabajadores/as Sociales en esta area se centra en el manejo de metodologias de intervencion a nivel individual, familiar, grupal y comunitario, manejo de herramientas tecnologicas; elaboracion y ejecucion de programas y/o proyectos; poseer conocimientos en promocion y educacion social, en planificacion y proyectos sociales, en gestion escolar y trabajo en equipo; poseer habilidades para establecer relaciones interpersonales; tener capacidad para resolver conflictos, para comunicarse en forma oral y escrita, para trabajar en equipos multidisciplinarios, para identificar y solucionar problemas; demostrar una actitud de compromiso, responsabilidad social y consistencia etica, tolerancia a la diversidad de opinion, pro actividad y respeto a la diversidad sociocultural. EnglishThe present work shows the role, the profile and the professional space of Social Workers in the Educational Field, specifically in public schools of five towns in Nuble’s Province, VIII Region of Bio-Bio. Some results and conclusions emphasize on the variety of functions that Social Workers perform in the Educational area and also indicates that the professional space in this field is wide and diverse. It also enhances the work these professionals have to do at a familiar level and the support they could give in the production and implementation of Institutional Educational Projects. The professional profile of Social Workers is focus on the management of interventions at an individual, familiar, group and community levels; the use of technological tools, production and implementation of programs or projects; to have knowledge in promotion and social education; in planning and social projects; in school administration and group work; to have abilities in establishing interpersonal relationships; to have the capacity to solve conflicts of oral and written communication, to work in multidisciplinary teams, to identify and solve problems, to show an attitude of commitment, social responsibility and ethic strength, tolerance to diversity of opinions and being proactive and respectful to sociocultural diversity.
Alveolar Type II Cells Expressing Jaagsiekte Sheep Retrovirus Capsid Protein and Surfactant Proteins Are the Predominant Neoplastic Cell Type in Ovine Pulmonary Adenocarcinoma (2002)

Ovine pulmonary adenocarcinoma is caused by jaagsiekte sheep retrovirus. To gain insight into the histogenesis and viral pathogenesis of this neoplasm, the tumor cell phenotypes and differentiation state were correlated with the distribution of jaagsiekte sheep retrovirus capsid protein in neoplastic and normal cells of the lung in nine naturally occurring and 12 experimentally induced cases of ovine pulmonary adenocarcinoma. Overall, 82% of tumor cells had ultrastructural features consistent with alveolar type II cells, 7% of tumor cells had features of Clara cells, and 11% of tumor cells were insufficiently differentiated to classify. The proportion of the neoplastic cell phenotypes varied within tumors, and no tumor consisted of a morphologically uniform cell population. To further characterize the neoplastic cell population, sections of tumors were immunostained with antibodies to surfactant protein A, surfactant protein C, and Clara cell 10-kd protein. Overall, surfactant proteins A and C were expressed in 70% and 80% of tumor cells, respectively, whereas Clara cell 10-kd protein was expressed in 17% of tumor cells. Jaagsiekte sheep retrovirus capsid protein was detected in 71% of tumor cells and in macrophages (5/21 tumors examined) and in nonneoplastic alveolar and bronchiolar cells (6/14 tumors). Expression of this viral protein in neoplastic cells, classified morphologically and by immunophenotyping primarily as of the alveolar type II lineage, implies an important role for specific virus-cell interactions in the pathogenesis of ovine pulmonary adenocarcinoma.
Effects of Recombinant Erythropoietin Therapy on Circulating Endothelial Markers in Hemodialysis Patients (2002)

Effects of a 4-week course of recombinant human erythropoietin (rHuEpo) therapy on four circulating endothelium-derived cardiovascular risk markers were studied in 20 patients receiving maintenance hemodialysis in relation to surrogates of chronic inflammation, liver function, and arterial blood pressure. Soluble intercellular adhesion molecule-1 (sICAM-1), antigens of plasminogen activator inhibitor-1 (PAI-1:Ag) and von Willebrand factor (vWF:Ag), and soluble thrombomodulin (sTM) were determined by immunoenzymatic assays. C-reactive protein; alpha1 acid-glycoprotein; alpha1-antitrypsin; immunoglobulin M, A, and G; interleukin-6; lipoprotein(a); fibrinogen; total protein; albumin; total cholesterol; hepatitis B and C markers; liver enzymes; prothrombin time; and phosphorus were measured by routine methods. The rHuEpo treatment resulted in a 25% increase in sICAM-1 (Wilcoxon's p = 0.001), a 50% increase in PAI-1:Ag (p = 0.004), a 15% increase in sTM (p = 0.002), and did not change vWF:Ag levels. The increase in sICAM-1 concentration directly correlated with that of PAI-1:Ag (Spearman's rho = 0.483, p = 0.031). The rHuEpo-induced increases in hemoglobin, platelets, and pre-dialysis diastolic blood pressure levels did not correlate with the increments in the endothelial markers studied. In conclusion, short-term rHuEpo therapy activates vascular endothelium in patients receiving maintenance hemodialysis. This specific effect may influence cardiovascular risk.
A SNR-insensitive Doppler shift estimator in wireless communications (2008)

This paper presents a signal-to-noise ratio (SNR) insensitive Doppler shift estimator based on the square envelope autocorrelation function (SEACF) of mobile propagation channels, where an iterative processing is employed to eliminate the approximation error and the effects of additive noise. Both theory and simulation show a good SNR-insensitive performance in a wide range of velocities and SNRs.