gebhart/patrepeval huggingface dataset:
Interleukin-HP1, a T cell-derived hybridoma growth factor that supports the in vitro growth of murine plasmacytomas. (1987)

We have recently described the purification and NH2-terminal amino acid sequence of a T cell-derived hybridoma growth factor that was provisionally designated interleukin-HP1 (IL-HP1). Here we report that a T cell supernatant containing high titers of this hybridoma growth factor considerably facilitated the establishment of primary cultures of murine plasmacytomas. Most plasmacytoma cell lines derived from such cultures remained permanently dependent on IL-HP1-containing T cell supernatant for both survival and growth in vitro. These cell lines, however, retained their ability to form tumors in irradiated pristane-treated mice. Analytical fractionation of a T cell supernatant rich in IL-HP1 by either gel filtration, isoelectric focusing, or reversed-phase HPLC revealed the existence of only one plasmacytoma growth factor activity that strictly copurified with IL-HP1, strongly suggesting the identity of both factors. This conclusion was further supported by the finding that IL-HP1 purified to homogeneity supported the growth of both B cell hybridomas and plasmacytomas. For half-maximal growth, plasmacytomas, however, required a concentration of IL-HP1 of approximately 30 pM, which is approximately 200 times higher than that required by B cell hybridomas. A clear difference in the specificity of IL-HP1 and B cell stimulatory factor 1 (BSF-1) was demonstrated by the finding that IL-HP1-dependent plasmacytomas did not survive in the presence of BSF-1, whereas helper T cell lines that proliferated in the presence of BSF-1 failed to respond to IL-HP1.
A high-pressure NMR probehead for measurements at 400 MHz (1994)

A new high-pressure NMR probehead designed for a 400 MHz widebore NMR spectrometer is described. For the first time, the electrical leads of the rf circuit, the tubes for the thermostating liquid and the high-pressure fluid, as well as the wires of the Pt-100 resistor for temperature control, are all fitted at the bottom of the high-pressure vessel. The sample can easily be removed through a top plug, which allows a relatively fast exchange of the sample. A rather simple design leads to a low-cost construction. The high-pressure vessel and the rf circuit are placed inside a standard probehead jacket, such that the high-pressure probehead can be fitted into the superconducting magnet in the same way as a commercial probehead.
Carbonation precipitation of manganese from electrolytic manganese residue treated by CO2 with alkaline additives (2016)

This work reports the results of carbonate precipitation of soluble manganese by CO 2 with alkaline additives with the aim of eliminating the harm caused by electrolytic manganese residue (EMR). Results showed that CaO exhibited a better performance for the precipitation of manganese which was converted to rhodochrosite (MnCO 3 ) by infrared spectra and XRD analyses and that the precipitation rate of manganese reached 99.99% at 800 mL/min CO 2 flow rate and 5% CaO for 20 min reaction time. The leached concentration of manganese of the treated EMR was reduced to 0.2 mg/L and the leached concentrations of heavy metals of the treated EMR were less than the discharge standard of China (GB8978-1996). Another interesting finding was that the pH value and the ORP of the treated EMR slurry were about 7 and 320 mV respectively, which favoured landfill and reuse of EMR.
Lateral Back-to-Back Diode for Low-Capacitance Transient Voltage Suppressor (2010)

In this paper, a transient voltage suppressor (TVS) using a native lateral back-to-back diode structure in conventional complementary metal–oxide–semiconductor (CMOS) technology is proposed. The capacitance, direct-current (DC) current–voltage ( I – V ) characteristics, and transmission line pulse (TLP) I – V characteristics of this lateral back-to-back diode are investigated. An optimization guideline for the lateral device is presented. The lateral structure is also suitable for the advanced wafer-level chip-scale package (WL-CSP) technology to meet the low capacitance and small footprint requirement for high-frequency or handheld device applications. This is a simple solution for a low-capacitance and low breakdown-voltage protection device against electrostatic discharge and electrical overstress in discrete or on-chip applications.
A global clinical measure of fitness and frailty in elderly people (2005)

Frailty is a valid and clinically important construct that is recognizable by physicians. Clinical judgments about frailty can yield useful predictive information.
A Fé e a Expansão (2000)

Para os portugueses, no inicio, a fe movia montanhas, mas posteriormente eles descobriram (e talvez tenha sido este o maior de seus descobrimentos) que a fe tambem movia montantes ou montanhas de dinheiro. Tal descoberta pode ser considerada o marco divisor de duas fases.
Liquid crystalline benzothiophene derivatives. Part 2: 2,5-disubstituted benzothiophenes (2011)

In the continuation of our study on heterocyclic mesogens, the structural motif of a 2,5-disubstituted benzothiophene as the central unit was utilised to design novel liquid crystals. Despite the bent molecular structure, the formation of a standard calamitic phase was observed. The mesomorphic properties of the model substances of series I was very close to that of the previously studied 6-substituted derivatives. Introduction of the chiral terminal unit led to appearance of the ferroelectric smectic C* (SmC*) phase in compounds IIa–d. 5-Phenylbenzothiophene based mesogens III exhibited higher clearing temperatures and polymorphism (nematic–smectic A–SmC sequence). Thus, the central benzothiophene unit can be successfully utilised in the design of various liquid crystals.
Prenatal Development of Parvalbumin Immunoreactivity in the Human Striate Cortex (1996)

In human primary visual cortex, parvalbumin (PV) is expressed by Cajal-Retzius cells in layer I by 20 weeks of gestation (20W), but its immunoreactivity is mostly lost by term. PV immunoreactivity in layers II-VI mainly develops later, from 26 to 34W, following an approximately 'inside-outside' sequence in a series of bands. PR-positive perikarya appear in layer V by 20W, but only in small numbers. They increase in number and staining intensity by 26W. By 30W a band of densely labelled somata and neuropil occupies layers IVC-VI. By 34W a second, less dense, band of cell bodies and neuropil appears in IVB and IVCalpha, separated from the deep band by IVCbeta which is cell-sparse and almost fibre-free. Between 38 and 40W, a third minor band consisting mainly of fibres is seen in layer IVA. Reactive cell bodies form clusters, and the neuropil staining is mosaic-like. PV-positive neurons are of two main types: large with wide dendritic arbor, and smaller with simpler dendrites. However, a few have characteristics of pyramidal cells, and a few others resemble glial cells. The laminar pattern of PV-immunoreactive somata in human striate cortex is established by term, rather than postnatally as in most mammals, implying that PV may be involved in neuronal development in prenatal human striate cortex.
Production of <i>Leuconostoc oenos</i> Biomass under pH Control (1989)

Leuconostoc oenos was grown on apple juice-based media. The effect of pH control on metabolism and biomass production was studied. Without pH control, L. oenos acidified the apple juice media to approximately pH 3.6. More than 75% of the malic acid was used under these conditions, but less than half of the carbohydrates was assimilated. Under pH control, biomass yields increased by 60%; most of the malic acid was used, but high levels of unfermented carbohydrates remained. The addition of tomato juice, vitamins, nucleotides, Mn, and malic acid did not permit further increases in the cell counts; however, malic acid did induce further acidification. Growth without pH control favored a more homofermentative metabolism. Biomass production was higher in filter-sterilized apple juice media compared with that in the autoclaved media.
Tumorigenicity Studies for Human Pluripotent Stem Cell-Derived Products (2013)

Human pluripotent stem cells (hPSCs), i.e. human embryonic stem cells and human induced pluripotent stem cells, are able to self-renew and differentiate into multiple cell types. Because of these abilities, numerous attempts have been made to utilize hPSCs in regenerative medicine/cell therapy. hPSCs are, however, also tumorigenic, that is, they can give rise to the progressive growth of tumor nodules in immunologically unresponsive animals. Therefore, assessing and managing the tumorigenicity of all final products is essential in order to prevent ectopic tissue formation, tumor development, and/or malignant transformation elicited by residual pluripotent stem cells after implantation. No detailed guideline for the tumorigenicity testing of hPSC-derived products has yet been issued for regenerative medicine/cell therapy, despite the urgent necessity. Here, we describe the current situations and issues related to the tumorigenicity testing of hPSC-derived products and we review the advantages and disadvantages of several types of tumorigenicity-associated tests. We also refer to important considerations in the execution and design of specific studies to monitor the tumorigenicity of hPSC-derived products.
Influence of Cobalt and Mycorrhizae Mediated Phosphorus on Some Higher Plants Growth and Yield (2012)

Two pot experiments were conducted to assess the effect of cobalt and mycorrhizae (Gigaspora gigantean) mediated phosphorus on the growth and yield of corn as monocots and soybean as dicots. Experiments were carried out at Wire house in National Research Centre, Egypt. Plastic pots (40 cm diameter) filled with silty clay soil and inoculated with mycorrhizae fungi before seeds sowing and fertilized by calcium mono phosphate at 50, 100 and 200 mg P/Kg soil. The seedlings (at the third truly leaf) were irrigated with cobalt sulphate once, with 0, 4, 8, 10, 12, 16 and 20 ppm cobalt. The obtained results can be summarized as follows: The growth of both corn and soybean plants, inoculated with low phosphorus level were significantly increased compared other levels.  The mycorrhizae colonies decreased as P increased while cobalt is not significant.  Cobalt at 10 ppm with mycorhizae had a significant promotive effect on growth, yield minerals composition and chemical content of corn compared with mycorrhizae alone.  Cobalt at 12 ppm with mycorrhizae gave a similar effect of soybean.  Phosphorus content of plants was nearly doubled in mycorrhizae and cobalt compared with mycorrhizae alone. It can be concluded that the cobalt with mycorrhizae inoculation under low phosphorus level enhanced the growth, yield quantity and quality in both corn and soybean, but this positive impact was more significant in the dicot plants compared to monocot.
Disk resident arrays: an array-oriented I/O library for out-of-core computations (2002)

In out-of-core computations, disk storage is treated as another level in the memory hierarchy, below cache, local memory, and (in a parallel computer) remote memories. However the tools used to manage this storage are typically quite different from those used to manage access to local and remote memory. This disparity complicates implementation of out-of-core algorithms and hinders portability. We describe a programming model that addresses this problem. This model allows parallel programs to use essentially the same mechanisms to manage the movement of data between any two adjacent levels in a hierarchical memory system. We take as our starting point the Global Arrays shared-memory model and library, which support a variety of operations on distributed arrays, including transfer between local and remote memories. We show how this model can be extended to support explicit transfer between global memory and secondary storage, and we define a Disk Resident Arrays Library that supports such transfers. We illustrate the utility of the resulting model with two applications, an out-of-core matrix multiplication and a large computational chemistry program. We also describe implementation techniques on several parallel computers and present experimental results that demonstrate that the Disk Resident Arrays model can be implemented very efficiently on parallel computers.
Study on keys of optical coarse packet switching based on optical multiwavelength label routing (2005)

A kind of optical coarse packet switching based on optical label routing is intrduced. In the switching, the swapping granularity is coarse compared to common optical packet switching, and the header of optical packet is labeled by multi-wavelengths. Some realization techniques on core switching node and edge node with terminator are studied. A principle experiment system is established to perform the optical coarse packet transmitting, switching, and receiving, and verify the feasibility of such optical coarse packet switching.
Quantitative Assessment of the Nematode Fauna Present on Geotrupes Dung Beetles Reveals Species-Rich Communities with a Heterogeneous Distribution (2010)

Pristionchus spp. nematodes exhibit several traits that might serve as pre-adaptations to parasitism. Under harsh environmental conditions, these nematodes can arrest development and form dauer larvae. In addition, they have been shown to live in necromenic association with a range of beetles, including dung beetles ( Geotrupes stercorosus ) on which, for example, Pristionchus entomophagus is commonly found. It has been argued that the formation of dauer larvae and the association with invertebrates represent intermediate steps towards parasitism. To better understand necromenic associations, and to gain information on Pristionchus spp. abundance and the general species composition on dung beetles, we extracted all the nematode fauna present on 114 individuals of G. stercorosus. By direct sequencing using the 18S SSU, we provide a barcode for all nematodes isolated from the beetle samples. In total, 5,002 dauer-stage nematodes were sequenced, which included Pristionchus spp., Koerneria spp. (Diplogastridae), Pelodera spp. (Rhabditidae), and Strongyloidea as well as Spirurida. Intensities of infection varied from over 1,000 nematodes isolated from a single G. stercorosus to none, with Pelodera spp. being the most abundant group isolated. This study presents the first quantitative data on the Pristionchus spp. infection of beetles.
Extraction of Organic Compounds from Aqueous Solutions (1994)

ADVERTISEMENT RETURN TO ISSUEPREVDemoNEXTExtraction of Organic Compounds from Aqueous SolutionsBrian Love Cite this: J. Chem. Educ. 1994, 71, 6, 517Publication Date (Print):June 1, 1994Publication History Received3 August 2009Published online1 June 1994Published inissue 1 June 1994https://doi.org/10.1021/ed071p517.2RIGHTS & PERMISSIONSArticle Views737Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
Electronic Spectroscopy and Photophysics of Si Nanocrystals: Relationship to Bulk c-Si and Porous Si (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectronic Spectroscopy and Photophysics of Si Nanocrystals: Relationship to Bulk c-Si and Porous SiL. E. Brus, P. F. Szajowski, W. L. Wilson, T. D. Harris, S. Schuppler, and P. H. CitrinCite this: J. Am. Chem. Soc. 1995, 117, 10, 2915–2922Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/ja00115a025https://doi.org/10.1021/ja00115a025research-articleACS PublicationsRequest reuse permissionsArticle Views1429Altmetric-Citations289LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An improved infiltration technique to test the pathogenicity of Xanthomonas oryzae pv. oryzae in rice seedlings (1996)

When testing the pathogenicity of Xanthomonas oryzae pv. oryzae by the standard leaf clipping technique, we normally observed a bleached, hypersensitive-like reaction preceding a general yellowing or browning of the tissue. Water-soaked lesions were seldom observed, even on plants in a lighted dew chamber at 100% RH. However, by using a plastic disposable 1.0-ml syringe modified to infiltrate rice leaves, water-soaked lesions developed in 5-7 days after infiltration with X. oryzae. Exudate was often evident after 8-10 days. The infiltration technique was compared to the leaf clipping technique by inoculating plants of rice cv IR-24 with six strains of X o. pv. oryzae from Asia, three strains of X. o. pv. oryzae (X1-5, X1-8, and X37-2) from Texas, four strains of X.o. pv. oryzicola, and two unknown yellow-pigmented bacteria (isolated from California rice seeds) in a commercial, lighted dew chamber. Inoculation by the clipping technique usually resulted in bleached or tan-colored lesions regardless of the organism used. Using the infiltration technique, narrow, dark green, water-soaked lesions consistently developed with all strains of X. o. pv. oryzae and X o. pv. oryzicola from Asia, but not with the Texas strains or the unknown bacteria. This simple infiltration technique should be very useful for the accurate determination of the pathogenicity of rice xanthomonads.
ENVIRONMENTAL ASPECTS OF COMPACTED MIXTURES OF FLY ASH AND WASTEWATER SLUDGE (1976)

The paper reports on a study to determine whether the resulting compacted mixtures would be physically suitable for use in highway embankments and other structural fills; and to determine the extent of adverse environmental effects, especially leaching of potentially harmful trace elements. The first objective was evaluated on the basis of unconfined compressive strength and permeability for samples compacted near the optimum moisture content. Evaluation of the second objective was based on analysis of simulated leachate. Measurements of the extent of biological degradation of organics in the sludge aided evaluation of both objectives.
Inhibition by ethanol of rat P2X<sub>4</sub> receptors expressed in <i>Xenopus</i> oocytes (2000)

1. The effect of ethanol on the function of P2X(4) receptors expressed in Xenopus oocytes was studied using two-electrode voltage-clamp recording. 2. The amplitude of current activated by 1 microM ATP was decreased by ethanol in a concentration-dependent manner over the concentration range 1 - 500 mM. The concentration of ethanol that produced 50% inhibition (IC(50)) of current activated by 1 microM ATP was 58 mM. 3. Ethanol inhibition of ATP-activated current was not dependent on membrane potential from -60 to +20 mV, and ethanol did not change the reversal potential of ATP-activated current. 4. Ethanol, 50 mM, shifted the ATP concentration-response curve to the right, increasing the EC(50) for ATP from 9.1 to 16.0 microM, but did not reduce the maximal response to ATP. 5. The results suggest that ethanol may inhibit P2X(4) receptors by decreasing the apparent affinity of the binding site for ATP. 6. Since the P2X(4) receptor is the most abundant P2X subunit in the brain, these receptors could be important effectors of ethanol action in the central nervous system.
Towards a Domain-Specific Language for geospatial data visualization maps with Big Data sets (2015)

Data visualization is an alternative for representing information and helping people gain faster insights. However, the programming/creating of a visualization for large data sets is still a challenging task for users with low-level of software development knowledge. Our goal is to increase the productivity of experts who are familiar with the application domain. Therefore, we proposed an external Domain-Specific Language (DSL) that allows massive input of raw data and provides a small dictionary with suitable data visualization keywords. Also, we implemented it to support efficient data filtering operations and generate HTML or Javascript output code files (using Google Maps API). To measure the potential of our DSL, we evaluated four types of geospatial data visualization maps with four different technologies. The experiment results demonstrated a productivity gain when compared to the traditional way of implementing (e.g., Google Maps API, OpenLayers, and Leaflet), and efficient algorithm implementation.
Towards improved calibration in the measurement of partial discharges in rotating machinery (2002)

It is pointed out that an improved calibration strategy for partial-discharge (PD) detectors in rotating machine applications can only be achieved if the propagation characteristics of PD pulses are clearly understood, thus enabling the calibration pulse to simulate the discharge pulse more accurately as it appears at the detector terminals. The results of a pulse propagation study are reported, and the available models which may be of use in explaining the observed phenomena are discussed. Two forms of experimental procedure were adopted. In both, a 6.6-kV motor stator was utilized. In the first, a discharge simulating/calibration pulse was injected at one phase terminal and detected at different intercoil links. In the second, similar pulses were injected at the intercoil links and detected at the phase terminals. Pulse response was monitored on a 400-MHz-bandwidth oscilloscope and stored with an associated digitizing camera. Stator models developed in the area of surge propagation are reviewed, providing useful insight into the mechanisms for pulse propagation and providing the basis for the development of a general pulse propagation model. Digital signal processing considerations are also examined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>