gebhart/patrepeval huggingface dataset:
Acoustic reflex in patients with cochlear implants (analog stimulation). (1991)

Stapedius reflexes were tested in 21 deaf patients with the Vienna cochlear implant using intra- or extracochlear electrodes. Sinusoidal bursts of 125, 500, 1,000 and 2,000 Hz were used as stimuli presented in a randomized sequence. The contralateral acoustic reflex was monitored by synchronized sampling of the acoustic impedance of the ear. Results obtained were compared to psychoacoustic sensation values. The reflex threshold always was located close to the uncomfortable loudness level within the subjective dynamic range, or at least above the most comfortable loudness level. Practical applications of reflex testing and limitations of the method for use in children are discussed.
Analysis of two asymmetric multiquantum well InGaAsP laser structures (1998)

Summary form only given. Two aspects of asymmetric MQW lasers are studied. First, the output of a well as a function of its position in the active region has been modeled and measured experimentally. The simulations predicted that wells near the p-side of the active region contribute more light than wells near the n-side. Second, the competition between wells of different thicknesses owing to the dependence of capture of carriers and gain on well thickness and well placement in the active region has been observed experimentally.
Resuscitation Room Survey (1969)

A survey of 100 seriously ill patients admitted to a Resuscitation Room is described. The survey was conducted over a comparatively short space of time, but it has nonetheless illustrated several facts. The remarkable frequency of violence and poisoning among patients requiring resuscitation is demonstrated. This combined group constitutes over 80 per cent of all the patients. Also notable is the frequency of head injury, and in particular the high percentage (75%) of patients who received their head injuries in road traffic accidents. The Neurosurgical Unit is shown to receive far more patients from the resuscitation room than any other unit, and this fact might be usefully employed in planning the proximity of such units to casualty departments of the future. The use of a specially equipped resuscitation room is described. It is clearly desirable to have such an area, but with the relatively small number of resuscitation patients it is not economical to restrict the very expensive X-ray facilities to these patients alone.
Synthesis and Upconversion Luminescence of Nanoparticles Y<sub>2</sub>O<sub>3</sub> and Gd<sub>2</sub>O<sub>3</sub> Co-doped with Yb<sup>3+</sup> and Er<sup>3+</sup> (2016)

Upconversion nanoparticles (UCNs) find application in nanomedicine as biolabels to identify cancer cells. In this work, Y2O3: Er3+/Yb3+ and Gd2O3: Er3+/Yb3+ systems were fabricated by combustion synthesis (CS) and sol-gel (SG) methods to obtain nanoparticles with different shapes and sizes after post-annealing treatments. The crystallinity and morphology were analysed by x-ray diffraction (XRD) and transmission electron microscopy (TEM), respectively, and the luminescent properties by spectrofluorescence measurements. The luminescence varied depending on the doping level. In this study, for the host Y2O3, with Er3+/Yb3+ (1%/1% mol), the green emission was more strongly attributed to the 2H 11/2→4I 15/2, 4S3/2→4I 15/2 transitions of Er3+ ions. Red emission was present in Yb3+ (5%/10% mol) due to the 4F9/2→4I15/2 transition for both hosts. For the host Gd2O3, green emission was present in Er3+ (2% mol) and Yb3+ (3% mol). The surface of some UCNs was coated with a thin silica layer and analysed in order to compare the luminescence with the uncoated UCNs. The purpose of the coating was to prepare the samples for further functionalization for biolabel use. Results show that the emission intensity of all samples strongly depends on the synthesis method. SG was more reliable than CS synthesis in producing UCNs with better morphology and luminescent properties.
Comprehensive Edge Detection Algorithm for Satellite Images (2013)

Edges are prominent features in images and their analysis and detection are an essential goal in computer vision and image processing. Indeed, identifying and localizing edges are a low level task in a variety of applications such as 3-D reconstruction, shape recognition, image compression, enhancement and restoration. In this paper, we considered edge detection as one of the technique and the evaluation metrics such as SSIM (Structural Similarity Index) and VIF(Visual Information Fidelity) has been applied to the images to measure the image quality. In this paper Satellite images with natural-color are considered, which are captured from the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Terra satellite. In the present work evaluation metrics are applied to the original image and edge detected image, thus from experimental results it is observed that the proposed algorithm works well for measuring the quality of hyper spectral images.
White-light electroluminescence from soluble oxadiazole-containing phenylene vinylene ether-linkage copolymer (2001)

We report a promising oxadiazole-containing phenylene vinylene ether-linkage copolymer, which can emit nearly white light from a single-layer light-emitting diode. The emission spectrum is composed of a red component originating from the new excited dimer in addition to the blue-green component from an individual lumophore and excimer. This excited dimer is formed under a strong electric field inside the diode and cannot be produced by photoexcitation, which is different from the excimer or exciplex that is often found both in photoluminescence and electroluminescence, and it is termed the “electromer.”
Phosphatidylserine Supplementation as a Novel Strategy for Reducing Myocardial Infarct Size and Preventing Adverse Left Ventricular Remodeling (2021)

Phosphatidylserines are known to sustain skeletal muscle activity during intense activity or hypoxic conditions, as well as preserve neurocognitive function in older patients. Our previous studies pointed out a potential cardioprotective role of phosphatidylserine in heart ischemia. Therefore, we investigated the effects of phosphatidylserine oral supplementation in a mouse model of acute myocardial infarction (AMI). We found out that phosphatidylserine increases, significantly, the cardiomyocyte survival by 50% in an acute model of myocardial ischemia-reperfusion. Similar, phosphatidylserine reduced significantly the infarcted size by 30% and improved heart function by 25% in a chronic model of AMI. The main responsible mechanism seems to be up-regulation of protein kinase C epsilon (PKC-ε), the main player of cardio-protection during pre-conditioning. Interestingly, if the phosphatidylserine supplementation is started before induction of AMI, but not after, it selectively inhibits neutrophil's activation, such as Interleukin 1 beta (IL-1β) expression, without affecting the healing and fibrosis. Thus, phosphatidylserine supplementation may represent a simple way to activate a pre-conditioning mechanism and may be a promising novel strategy to reduce infarct size following AMI and to prevent myocardial injury during myocardial infarction or cardiac surgery. Due to the minimal adverse effects, further investigation in large animals or in human are soon possible to establish the exact role of phosphatidylserine in cardiac diseases.
Practical Guide to Interpretive Near-Infrared Spectroscopy (2007)

Containing focused, comprehensive coverage, Practical Guide to Interpretive Near-Infrared Spectroscopy gives you the tools necessary to interpret NIR spectra. The authors present extensive tables, charts, and figures with NIR absorption band assignments and structural information for a broad range of functional groups, organic compounds, and
The Tail of the Telomere (2008)

The structure of a higher-order G-quadruplex structure for human telomeric DNA is presented. The structure was determined by a novel integrated approach in which molecular dynamics simulations were used to produce a stable structure, from which specific experimentally accessible properties were predicted. These properties were tested by sedimentation velocity and steady-state fluorescence measurements. The structure that emerges is a dimeric structure with two quadruplex units, each with a different structure. The interface between the quadruplex units is stabilized by specific stacking interactions of loop nucleotides. The interface is a unique structure and a unique target for drug design.
The dihydroisoindole approach to linearly annelated π-extended porphyrins (2009)

The dihydroisoindole strategy for the synthesis of linearly annelated π-extended porphyrins is a common approach to tetrabenzo-, tetranaphtho-, and tetraanthraporphyrins with variable functionality and substitution patterns. This method implies the use of a common type of precursors involving the 4,7-dihydroisoindole moiety, which are the closest possible stable relatives of the unstable isoindole, benzoisoindole and naphthoisoindole. A key feature of this strategy is the unprecedented mildness of the final oxidative aromatization step, which accounts for synthetic versatility, better functional group tolerance and high purity of the products. Many new linearly annelated π-extended porphyrins of the tetrabenzo-, tetranaphtho-, and tetraanthraporphyrin families were produced and characterized for the first time, including soluble planar and highly emissive 5,15-diaryl derivatives. The double bond of the dihydroisoindole fragment can also be useful for further modification of the porphyrin by means of addition of cycloaddition reactions, leading to new, previously inaccessible porphyins bearing multiple halide, hydroxy, or acetoxy groups at the periphery.
Application of non-linear analysis techniques to sigma-delta modulators (1997)

In the past sigma-delta modulators have been analysed using linear analysis techniques. In these approaches the quantiser is replaced by an additive white noise source and then standard linear systems analysis is applied. This approach can provide good estimates of noise performance but it is unable to explain much of the behaviour of sigma-delta modulators, especially such phenomena as instability, integrator spans, quantiser switching frequency, idle tones, strong limit cycle behaviour and chaos, which are inherently non-linear. To examine these problems it will be necessary to utilise some of the many non-linear analysis techniques now available. A full rigorous non-linear analysis of these systems using any one technique would be very difficult, if not impossible. An alternative is to identify specific problems, such as instability, and to apply the most suitable non-linear analysis technique to the problem. Three main approaches have been applied to the non-linear analysis of sigma-delta modulators: spectral analysis (noise and signal performances), geometric analysis (stability analysis and integrator spans) and non-linear dynamics (limit cycle behaviour).
Fibre optic distributed sensor in Mach-Zehnder interferometer configuration (2003)

This paper describes the conception of the new generation sensor in double Mach-Zehnder interferometer configuration. Such configuration makes it possible to detect the disturbance places of a guarded area. Also requirements to sensors with distributed sensitivity for object outer guard are presented in the article.
Steroid 21-hydroxylase deficiency: two additional mutations in salt-wasting disease and rapid screening of disease-causing mutations (1993)

A method for genetic diagnosis of steroid 21-hydroxylase deficiency was developed based on allele-specific PCR. With this approach, genotyping of fourteen mutations and diagnosis of homozygous gene deletions can be performed within hours from tissue sampling. One patient with salt-wasting disease had normal genotype at all positions screened. DNA sequencing revealed two novel mutations, a G to C transversion at the conserved splice donor site of intron 7 and a TGG to TAG nonsense mutation at Trp 406 in exon 9. Allele-specific PCR was established also for these mutations and used to screen for their presence in the pseudogene. However, the two novel mutations were not found in at least 34 pseudogenes.
Impaired Masking Responses to Light in Melanopsin‐Knockout Mice (2003)

There are two ways in which an animal can confine its behavior to a nocturnal or diurnal niche. One is to synchronize an endogenous clock that in turn controls the sleep-wake cycle. The other is to respond directly to illumination with changes in activity. In mice, high illumination levels suppress locomotion (negative masking) and low illumination levels enhance locomotion (positive masking). To investigate the role of the newly discovered opsin-like protein melanopsin in masking, we used 1 h and 3 h pulses of light given in the night, and also a 3.5:3.5 h light-dark (LD) cycle. Mice lacking the melanopsin gene had normal enhancement of locomotion in the presence of dim lights but an impaired suppression of locomotion in the presence of bright light. This impairment was evident only with lights in the order of 10 lux or brighter. This suggests that melanopsin in retinal ganglion cells is involved in masking, as it is in pupil contraction and phase shifts. Melanopsin is especially important in maintaining masking responses over long periods.
Classic and Adaptive Washout Comparison for a Low Cost Driving Simulator (2005)

The paper deals with control of small driving simulator SIM comparing the useless of adaptive and classic approaches. Driving simulators are considering as an interactive virtual reality tools, which take a considerable place in the human factors studies. The difficulty to reproduce in reality some drive situations mainly for risk and reproducibility reasons increases the interest of this tool. Nevertheless, the validation of the experiments carried out on driving simulator is closely related to embedding realism of the driver in the simulated world. In this article, we present the design of a low cost and small motion platform, which allow the restitution of 2 DOF movements. This overall system is considered as two independent systems linked mechanically. The first system consists in motorized rail for the longitudinal movement while the second system consists in motorized seat allowing either pitch movement of this one or just back seat inclination (this case would not be discussed in the rest of paper)
Energy-aware scheduling for real-time multiprocessor systems with uncertain task execution time (2007)

This paper presents an energy-aware method to schedule multiple real-time tasks in multiprocessor systems that support dynamic voltage scaling (DVS). The key difference from existing approaches is that we consider the probabilistic distributions of the tasks' execution time to partition the workload for better energy reduction. We analyze the problem of energy-aware scheduling for multiprocessor with probabilistic workload information and derive its mathematical formulation. As the problem is NP-hard, we present a polynomial-time heuristic method to transform the problem into a probability-based load balancing problem that is then solved with worst-fit decreasing bin-packing heuristic. Simulation results with synthetic, multimedia, and stereo-vision tasks show that our method saves significantly more energy than existing methods.
Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure (1995)

Oligomerization of the human immunodeficiency virus type 1 envelope (env) glycoproteins is mediated by the ectodomain of the transmembrane glycoprotein gp41. We report that deletion of gp41 residues 550 to 561 resulted in gp41 sedimenting as a monomer in sucrose gradients, while the gp160 precursor sedimented as a mixture of monomers and oligomers. Deletion of the nearby residues 571 to 582 did not affect the oligomeric structure of gp41 or gp160, but deletion of both sequences resulted in monomeric gp41 and predominantly monomeric gp160. Deletion of residues 655 to 665, adjacent to the membrane-spanning sequence, partially dissociated the gp41 oligomer while not affecting the gp160 oligomeric structure. In contrast, deletion of residues 510 to 518 from the fusogenic hydrophobic N terminus of gp41 did not affect the env glycoprotein oligomeric structure. Even though the mutant gp160 and gp120 molecules were competent to bind CD4, the mutations impaired fusion function, gp41-gp120 association, and gp160 processing. Furthermore, deletion of residues 550 to 561 or 550 to 561 plus 571 to 582 modified the antigenic properties of the proximal residues 586 to 588 and the distal residues 634 to 664. Our results indicate that residues 550 to 561 are essential for maintaining the gp41 oligomeric structure but that this sequence and additional sequences contribute to the maintenance of gp160 oligomers. Residues 550 to 561 map to the N terminus of a putative amphipathic alpha-helix (residues 550 to 582), whereas residues 571 to 582 map to the C terminus of this sequence.
Synchronous optical demultiplexing and sampling of 80-Gb/s OTDM signals by optically recovered clock using mode-locked laser diode and symmetric Mach-Zehnder switch (2002)

A demonstration of optical demultiplexing of an 80-Gb/s signal through a fiber transmission line by using an injection mode-locked laser diode (LD) to perform all-optical subharmonic clock recovery to control a symmetric Mach-Zehnder demultiplexer is described. Moreover, simultaneous optical sampling by the recovered clock was also demonstrated.
Numerical Valuation of High Dimensional Multivariate European Securities (1995)

We consider the problem of pricing a contingent claim whose payoff depends on several sources of uncertainty. Using classical assumptions from the Arbitrage Pricing Theory, the theoretical price can be computed as the discounted expected value of future cash flows under the modified risk-neutral information process. Although analytical solutions have been developed elsewhere for a few particular option pricing problems, computing the arbitrage prices of securities under several sources of uncertainty is still an open problem in many instances. In this paper, we present efficient numerical techniques based upon Monte Carlo simulation for pricing European contingent claims depending on an arbitrary number of risk sources. We introduce in particular the method of quadratic resampling (QR), a new powerful error reduction technique for Monte Carlo simulation. Quadratic resampling can be efficiently combined with classical variance reduction methods such as importance sampling. Our numerical experiments show that the method is practical for pricing claims depending on up to one hundred underlying assets.
Use of Stress Waves for Determining the Depth of Surface-Opening Cracks in Concrete Structures (1996)

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Characterization of a monoclonal antibody directed to a T cell suppressor factor. (1983)

A monoclonal antibody raised by fusion of immune BALB/c splenocytes with NS1 cells is described. BALB/c mice were immunized with a T suppressor factor (TsF) raised in DBA/2 mice with specificity for the P815 tumor. The TsF had been purified by affinity chromatography before its use as an immunogen. The monoclonal antibody (B16G) was shown to affect the course of P815 growth in DBA/2 mice if administered i.v. on days -2 to 0 before tumor cell inoculation. Mice treated with B16G demonstrated slower tumor development and growth than controls, and a small number of animals (about 10%) did not develop tumors; all controls did. It was also shown that B16G did not exhibit total specificity for the P815 tumor in that it had similar effects on the growth of an unrelated myosarcoma (M-1) of DBA/2 mice. The general immunopotentiating effect of the B16G monoclonal was demonstrated by the fact that spleen cells of DBA/2 mice that had received B16G showed significantly higher MLC than did equivalent controls. When spleen cells of DBA/2 mice were depleted of B16G-reactive cells by panning in vitro, it was also found that cells so treated gave rise to elevated MLC reactions in comparison to appropriate controls. When an immunoadsorbent was prepared with B16G and cell lysates from splenocytes of immunosuppressed mice were passed over it, the immunosuppressive properties of the lysate in MLC were eliminated. The conclusion that the B16G recognizes a marker common to a group of regulatory T cells in DBA/2 mice is discussed.
A Triple Hybrid Interconnect for Many-Cores: Reconfigurable Mesh, NoC and Barrier (2010)

Networks-on-chip (NoC) are very efficient for point-to-point communication but are also known to provide poor broadcast and multicast performance. In this paper, we propose a triple hybrid interconnect for many-cores, consisting of a reconfigurable mesh network and a wormhole routed NoC for data communication, and a barrier network for synchronization. On an FPGA many-core prototype comprising up to 30 Microblaze soft cores we show that the reconfigurable mesh network excels for multicast and broadcast operations, while the NoC performs better for larger messages and more dynamic workloads. Experiments with a parallel Jacobi algorithm demonstrate that the combined use of all three networks delivers the highest performance.
Crowdsourcing: How to Benefit from (Too) Many Great Ideas (2013)

This article focuses on how companies can cope with the enormous volume and variety of data (big data) that is acquired on crowdsourcing platforms from the worldwide community of Internet users. We identify the challenges of implementing crowdsourcing platforms and show how CIOs and other organizational leaders can build the absorptive capacity necessary to extract business value from crowdsourced data.Click here for free 2-page executive summary (pdf)
Contrast sensitivity and glare disability after implantation of AcrySof IQ Natural aspherical intraocular lens (2007)

Eyes with the AcrySof IQ SN60WF IOL had significantly higher contrast sensitivity than eyes with an AcrySof SA60AT or AcrySof Natural SN60AT IOL at all spatial frequencies during mesopic testing (with and without glare) with 4.0 and 6.0 mm artificial pupil.
Long Lasting Local and Systemic Inflammation after Cerebral Hypoxic ischemia in Newborn Mice (2012)

Our findings demonstrate activation of both local and systemic immune responses months after hypoxic ischemic neonatal brain injury. The long term immune activation observed is of general importance for future studies of the inflammatory response after brain injury as most previous studies have focused on the first few weeks after damage, while the effects of the late inflammation phase may be missed. Furthermore, the self-reactive component raises the question if there is a correlation with development of autoimmune brain disease later in life.
Bone Mineral Density in Children and Adolescents With Prader-Willi Syndrome: A Longitudinal Study During Puberty and 9 Years of Growth Hormone Treatment (2015)

This long-term GH study demonstrates that BMDTB, BMDLS, and BMADLS remain stable in prepubertal children with PWS but decreases during adolescence, parallel to incomplete pubertal development. Based on our findings, clinicians should start sex hormone therapy from the age of 11 years in girls and 14 years in boys unless there is a normal progression of puberty.