gebhart/patrepeval huggingface dataset:
Spin Hall effect and spin swapping in diffusive superconductors (2017)

We consider the spin-orbit-induced spin Hall effect and spin swapping in diffusive superconductors. By employing the nonequilibrium Keldysh Green's function technique in the quasiclassical approximation, we derive coupled transport equations for the spectral spin and particle distributions and for the energy density in the elastic scattering regime. We compute four contributions to the spin Hall conductivity, namely, skew scattering, side jump, anomalous velocity, and the Yafet contribution. The reduced density of states in the superconductor causes a renormalization of the spin Hall angle. We demonstrate that all four of these contributions to the spin Hall conductivity are renormalized in the same way in the superconducting state. In its simplest manifestation, spin swapping transforms a primary spin current into a secondary spin current with swapped current and polarization directions. We find that the spin-swapping coefficient is not explicitly but only implicitly affected by the superconducting gap through the renormalized diffusion coefficients. We discuss experimental consequences for measurements of the (inverse) spin Hall effect and spin swapping in four-terminal geometries. In our geometry, below the superconducting transition temperature, the spin-swapping signal is increased an order of magnitude while changes in the (inverse) spin Hall signal are moderate.
Therapeutic Effects of Kangxian Capsule on the Hepatic Fibrosis in Rats (2012)

Objective:To study the therapeutic effects of Kangxian capsule,a Chinese patent medicine,on the hepatic fibrosis in rats.Method:Forty male SD rats were randomly divided into normal control group,model group,colchicine group,Kangxian capsule high dose and low dose group.In order to prepare the hepatic fibrosis model,all the rats except those of the normal control group were subcutaneously administrated with the CCL4 olive oil solution for six weeks and were given high-fat diet in the first two weeks.The treatment groups were given different doses of Kangxian capsule and colchicine intervention for six weeks.The control group and model group animals were intragastrically fed with the same volume of normal saline.The activities of alanine aminotransferase(ALT) and aspartate aminotransferase(AST) in rat sera were detected with automatic biochemistry analyzer.The concentrations of hyaluronic(HA),laminin(LN),typeⅢ procollagen(PCⅢ)in sera were measured with the method of radioimmunoassay.The pathohistological changes were observed under microscope.Result:Compared with the model group,the serum levels of ALT,AST,HA,LN,PCⅢ in rats of Kangxian capsule treatment groups were significantly lower(P0.01).There were much degeneration and necrosis,inflammatory cell infiltration,false lobular formation,and a large number of collagen fiber depositions in liver tissue of the model group.Compared with the model group,the level of chronic hepatic damage was improved greatly and none of the false lobular formed in two dose of Kangxian capsule groups.Conclusion:Kangxian capsule can greatly protect from hepatic fibrosis in rats induced by CCL4.
Cutting Edge: The Acquisition of TLR Tolerance during Malaria Infection Impacts T Cell Activation (2005)

An effective immune response to infection requires control of pathogen growth while minimizing inflammation-associated pathology. During malaria infection, this balance is particularly important. Murine malaria is characterized by early production of proinflammatory cytokines, which declines in the face of continuing parasitemia. The mechanism by which this occurs remains poorly understood. In this study, we investigated the role of dendritic cells (DCs) in regulating pro- and anti-inflammatory cytokine responses. As malaria infection progresses, DCs become refractory to TLR-mediated IL-12 and TNF-alpha production, while increasing their ability to produce IL-10 and retaining the capacity for activation of naive T cells. IL-12-secreting DCs from early infection stimulate an IFN-gamma-dominated T cell response, whereas IL-10-secreting DCs from later stages induce an IL-10-dominated T cell response. We suggest that phenotypic changes in DCs during Plasmodium yoelii infection represent a mechanism of controlling host inflammation while maintaining effective adaptive immunity.
Telomerase regulation during entry into the cell cycle in normal human T cells. (1996)

Telomerase activity is involved in telomere length maintenance. Leukocytes, unlike many human somatic tissues, have detectable telomerase activity. These cells provide a normal human cell type in which to study telomerase. We studied the regulation of telomerase activity and the telomerase RNA component as leukocytes were stimulated to enter the cell cycle. In primary human leukocytes stimulated with phytohemagglutinin, telomerase activity increased > 10-fold as naturally quiescent cells entered the cell cycle. Antibodies to the T cell receptor (TCR)/CD3 complex and the costimulatory CD28 receptor induced telomerase activity in a T cell-enriched population of cells. Rapamycin, an immunosuppressant that blocks TCR/CD3 signal transduction pathways and cdk2 activation, blocked telomerase induction. Hydroxyurea, an inhibitor of S phase, did not block cdk2 kinase activity or telomerase activation. In summary, telomerase is regulated in G1 phase as normal human T cells enter the cell cycle.
Your history, my narrative: uncovering me through you (2004)

This paper examines three books, Khul-Khaal 1 , Doing Daily Battle 2 and Both Right and Left Handed 3 , all of which were published in the 1980s. Their subtitles, Five Egyptian Women Tell Their Stories, Interviews with Moroccan Women and Arab Women Talk About Their Lives respectively, indicate that all three books contain life stories of women from Arab countries. These books, then, fall into one category, not only because of their subject matter but also because they raise similar sets of questions relating to their technique and conditions of production.
Argininosuccinate synthetase and argininosuccinate lyase are localized around mitochondria: an immunocytochemical study. (1996)

Argininosuccinate synthetase and argininosuccinate lyase are soluble cytoplasmic enzymes of the urea cycle. Previous biochemical studies using permeabilized hepatocytes showed that these enzymes are organized in situ, and function as if they are located next to the outer membrane of mitochondria. We have now confirmed and extended those observations in intact liver by means of immunocytochemistry at the electron microscope level. Morphometric analysis of the electron micrographs shows that argininosuccinate synthetase and argininosuccinate lyase are located in the immediate vicinity of the mitochondria, predominantly next to the cytoplasmic surface of the outer membrane. Some immuno-specific protein is also observed in the endoplasmic reticulum in the immediate vicinity of the mitochondria. These results support our previous biochemical findings, and additionally suggest that virtually all of the argininosuccinate synthetase and argininosuccinate lyase of the liver parenchymal cell are located just outside the mitochondria.
Automated Testing of Power Supplies (1979)

The paper describes the hardware and software methods used to effectively test and diagnose DC to DC converters. The design requirements for the programmable sources and loads are described and the measurement schemes for ripple and alarm tests. The converter test set is presented as a part of a larger computer aided manufacturing sytem with two levels of hierarchy that follows the product from the laboratory to its end use.
Preoperative Evaluation of the Adult Outpatient (2011)

In the outpatient setting the preoperative anesthesia assessment – which exists in a variety of forms is a key tool for both optimizing medical and administrative outcomes. Proactive identification and management of medical problems avoids last minute surprises that at best interrupt ambulatory surgery center patient flow and at worst contribute to adverse medical outcomes. This lecture will review: 1) the basic requirements for preoperative evaluation as determined by payers and regulators 2) models of preoperative evaluation and their merits and 3) preanesthetic evaluation of selected co-morbidities which are particularly relevant to the outpatient setting such as obesity, sleep apnea, cardiac disease, and insulin requiring diabetes.
Design and implementation of energy efficient vedic multiplier using FPGA (2015)

The performance of the DSP applications mainly depends on the multiplier, because the multiplication requires more iterations, long time and large area of the system than other computations. Hence to improve the performance of the system it is required to have high speed and low power consumption multiplier. In this paper we proposed the comparative study of two different algorithms, first one is the conventional method called as "Booth Multiplier" and other is the vedic method "Nikhilam Navatascaram Dasatah" using reversible logic gates. Both the multipliers are designed and implemented by using Xilinx 13.2 ISE simulator. Comparative results of both the multipliers are analyzed in terms of delay, area and power consumption.
Matched Subspace Detection With Hypothesis Dependent Noise Power (2008)

We consider the problem of detecting a subspace signal in white Gaussian noise when the noise power may be different under the null hypothesis - where it is assumed to be known - and the alternative hypothesis. This situation occurs when the presence of the signal of interest (SOI) triggers an increase in the noise power. Accordingly, it may be relevant in the case of a mismatch between the actual SOI subspace and its presumed value, resulting in a modelling error. We derive the generalized likelihood ratio test (GLRT) for the problem at hand and contrast it with the GLRT which assumes known and equal noise power under the two hypotheses. A performance analysis is carried out and the distributions of the two test statistics are derived. From this analysis, we discuss the differences between the two detectors and provide explanations for the improved performance of the new detector. Numerical simulations attest to the validity of the analysis.
Synthese von 5‐(α‐<scp>D</scp>‐Glucopyranosyloxymethyl)‐3‐(β‐<scp>D</scp>‐ribofuranosyl)uracil und 3‐(2‐Desoxy‐β‐<scp>D</scp>‐ribofuranosyl)‐5‐(‐<scp>D</scp>‐glucopyranosyloxymethyl)uracil als Analoga eines DNA‐Bausteins (1974)

Abstract 5‐(α‐ D ‐Glucopyranosyloxymethyl)uridin ( 4a ), 5‐(α‐ D ‐Glucopyranosyloxymethyl)‐2′‐desoxyuridin ( 6a ) sowie sein β‐Anomeres 5a erhält man durch Reaktion der Aglykone 1 bzw. 2 mit 2,3,4,6‐Tetra‐ O ‐acetyl‐β‐ D ‐glucopyranose ( 3 ) in Gegenwart von Bortrifluorid‐ätherat und Abspaltung der Schutzgruppen. Die Konfiguration an C‐1 der Kohlenhydratkomponente dieser neuen Klasse von Pyrimidin‐nucleosiden wurde durch 1 H‐NMR‐Spektroskopie bestimmt.
A corpus of clinical narratives annotated with temporal information (2012)

Clinical reports often include descriptions of events in the patient's medical history, as well as explicit or implicit temporal information about these events. We are working towards applying deep Natural Language Processing tools towards understanding such narratives. This requires both the extraction and classification of the relevant events, and the placing of those events in time, or at least in relation to one another. Although several corpora of news data exist that have been annotated using the TimeML schema, similar corpora of clinical reports are not readily available.
Molecular and cellular mechanisms of chemical carcinogenesis. (1976)

Clearly, the technics of transformation in epithelial cell cultures bring us closer to understanding chemical carcinogenesis. Also clear is the need to develop new technics to evaluate the significance of viral particles found in tumors and to answer the basic question as to whether mutation or aberrant differentiation is the mechanism of chemical carcinogenesis.
Non-isotropic shadow effect with various pattern direction in anamorphic high numerical aperture system (2016)

Even though EUV lithography has extremely short wavelength source, a high numerical aperture(NA) system larger than 0.5 is required to make fine pattern of 1X nm and below. In order to avoid reflective efficiency loss and increase of chief ray angle of incident light, anamorphic high NA is suggested. Suggested anamorphic NA system has non-isotropic magnification which is varied 4X to 8X and the mask NA shape is ellipse due to non-isotropic magnification distribution. Anamorphic NA system has a non-conventional shadow effect due to non-isotropic incident angle distribution and magnification. These non-isotropic characteristics leads the reduction of asymmetric shadow distribution and it involves the reduction of horizontal-vertical bias. As a result anamorphic NA system can achieve balanced patterning results regardless of pattern direction and incident direction.
Crossover pharmacokinetics (PK) study to assess oral administration of abiraterone acetate capsule and tablet formulations in fasted and fed states in patients with prostate cancer (2008)

5168 Background: Abiraterone acetate (A) is an oral compound with metabolites that selectively inhibit CYP 17(17OH/ 17,20 lyase), blocking adrenal androgen synthesis and exhibiting anti-tumor activity in castration resistant prostate cancer (CRPC). Methods: Patients were divided into fed or fasted groups, and treated at 1000mg/day as a single dose in either capsule or tablet formulation on day 1, then the opposite formulation one week later on day 8, and from day 15, continuous dosing of 1000mg of the tablet formulation. PK samples were taken pre-dose and 1, 2, 4, 6, 8, 24, 48 and 72 hr post dose on days 1 and 8. Statistical analysis employed a two- period crossover model, using non-compartmental analysis. Results: A was well tolerated and side effects readily managed by mineralocorticoid antagonists. Overall 31 patients were enrolled, with PK results from 19 patients presented here. Area under the curve (AUC), was not significantly different between the two formulations for either the fed (p=0.412) or the fasted (p=0.334) states. However, there was a significantly higher mean Cmax in the fed state compared with the fasted state for both formulations: mean Cmax (nmol/l) capsules: (fed) 1469 vs (fasted) 286, p= 0.005; mean Cmax (nmol/l) tablets: (fed) 1573 vs (fasted) 324, p=0.004. AUC was also significantly higher in the fed state than in the fasted state for both formulations: AUC (hr*nmol/l) capsules: (fed) 10978 vs (fasted) 3249, p<0.001; AUC (hr*nmol/l) tablets: (fed) 10782 vs (fasted) 3090, p<0.001. Antitumor activity was observed as indicated by PSA declines, radiological responses, and symptomatic benefit. Conclusions: Similar Cmax and AUC were observed after administration of capsule and tablet formulations of A irrespective of fed or fasted state, suggesting bioequivalence. However both of these PK parameters were significantly higher in fed patients. Pharmacokinetic parameters comparing capsules with tablets Tmac (hr) Cmax (nmol/l) Terminal half life (hr) AUC (hr*nmol/l) Total body clearance (L/hr) Volume of distribution (L) Capsules (Fed) Mean 3.491 1469 13.8 10978 307 6254 Standard deviation (SD) 2.25 1156 2.35 3602 194 4686 Tablets (fed) Mean 3.176 1573 16.8 10782 341 7546 SD 1.69 1218 6.17 4732 255 4251 Capsules (fasted) Mean 3.068 286 16.8 3249 2094 30566 SD 1.64 161 11.4 2005 2846 35337 Tablets (fasted) Mean 2.098 324 16.7 3090 1308 35566 SD 0.70 215 10.4 2127 866 44766 Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Expert Testimony Other Remuneration Cougar Biotechnology Cougar Biotechnology
Label-Free Detection of Melittin Binding to a Membrane Using Electrochemical-Localized Surface Plasmon Resonance (2008)

Localized surface plasmon resonance (LSPR) and electrochemistry measurements connecting to core-shell structure nanoparticle are successfully exploited in a simultaneous detectable scheme. In this work, the surface plasmon band characterizations of this nanostructure type are initially examined by controlling the core size of the silica nanoparticle and shell thickness of the deposited gold. These results clearly show that when the shell thickness is increased, keeping the core size constant, the peak wavelength of the LSPR spectra is shifted to a shorter wavelength and the maximum of peak intensity is achieved at a particular shell thickness. On the basis of this structure, we present a membrane-based nanosensor for optically detecting the binding of peptide toxin melittin to hybrid bilayer membrane (HBM) and electrochemically assessing its membrane-disturbing properties as a function of concentrations. It will open up the way to detect functionally similar protein toxins and other membrane-targeting peptides with the intension of integrating this chip into a microfluid and expanding it into multiarray format.
Characterization of surface-undoped In/sub 0.52/Al/sub 0.48/As/In/sub 0.53/Ga/sub 0.47/As/InP high electron mobility transistors (1990)

High-performance 0.3- mu m-gate-length surface-undoped In/sub 0.52/Al/sub 0.48/As/In/sub 0.53/Ga/sub 0.47/As/InP high-electron-mobility transistors (HEMTs) grown by molecular beam epitaxy (MBE) have been characterized and compared with a surface-doped structure. At 18 GHz, the surface-undoped HEMT has achieved a maximum stable gain (MSG) of 19.2 dB compared to 16.0 dB for the surface-doped structure. The higher MSG value of the surface-undoped HEMTs is obtained due to the improved g/sub m//g/sub 0/ ratio associated with the surface-induced electric field spreading effect. Comparison of identical 0.3-*150- mu m-gate devices fabricated on surface-undoped and -doped structures has shown greatly improved gate leakage characteristics and much lower output conductance for the surface-undoped structure. It is demonstrated that the surface potential, modulated by different surface layer designs, affects the charge control in the conducting channel, especially the carrier injection into the buffer, resulting in excess output conductance. Several millimeter-wave coplanar waveguide (CPW) monolithic distributed amplifiers have been successfully fabricated by using the surface-undoped HEMT structure. A high gain per stage distributed amplifier with 170-dB+or-1-dB small-signal gain across a frequency band of 24-40 GHz, a W-band monolithic integrated circuit with 6.4-dB gain at 94 GHz, and a broad bandwidth distributed amplifier with 5-dB gain across a frequency band of 5 to 100 GHz have been demonstrated by using the surface-undoped structures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Orientation dependence of coupling between Lamb and shear horizontal waves in (1-x)Pb(Mg<inf>1/3</inf>Nb<inf>2/3</inf>)O<inf>3</inf>-xPbTiO<inf>3</inf> single crystal plates (2009)

The orientation dependence of coupling between Lamb and shear horizontal (SH) waves in [001] <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> and [011] <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> poled (1-x)Pb(Mg <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1/3</sub> Nb <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2/3</sub> )O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> -xPbTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (PMN-xPT) single crystal plates has been studied theoretically. For a [001] <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> polarized PMN-PT crystals plate there is no coupling between Lamb and SH waves when thetas = npi/4 (n = 0,1, 2, ...),and the strongest coupling occurs when thetas = (2n +1)pi/8 . For a [011] <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> polarized PMN-PT crystal plate, the decoupling and strongest coupling happen when thetas = npi/2 and thetas = (2n +1)pi/4 , respectively. Guided wave propagation for coupled and decoupled cases and for symmetric and antisymmetric modes are calculated explicitly. The results are useful for the design of guided wave devices using PMN-xPT single crystals.
Space Fortress game training and executive control in older adults: A pilot intervention (2011)

We investigated the feasibility of using the Space Fortress (SF) game, a complex video game originally developed to study complex skill acquisition in young adults, to improve executive control processes in cognitively healthy older adults. The study protocol consisted of 36 one-hour game play sessions over 3 months with cognitive evaluations before and after, and a follow-up evaluation at 6 months. Sixty participants were randomized to one of three conditions: Emphasis Change (EC)--elders were instructed to concentrate on playing the entire game but place particular emphasis on a specific aspect of game play in each particular game; Active Control (AC)--game play with standard instructions; Passive Control (PC)--evaluation sessions without game play. Primary outcome measures were obtained from five tasks, presumably tapping executive control processes. A total of 54 older adults completed the study protocol. One measure of executive control, WAIS-III letter-number sequencing, showed improvement in performance from pre- to post-evaluations in the EC condition, but not in the other two conditions. These initial findings are modest but encouraging. Future SF interventions need to carefully consider increasing the duration and or the intensity of the intervention by providing at-home game training, reducing the motor demands of the game, and selecting appropriate outcome measures.
A combined objective lens-energy analyser for electron beam testing of IC (1998)

Journal Article A combined objective lens-energy analyser for electron beam testing of IC Get access T.-T. Tang, T.-T. Tang Electronic and Information Engineering School, Xi'an Jiaotong UniversityXi'an, Shaanxi 710049, Peoples Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Y. Wang, Y. Wang Electronic and Information Engineering School, Xi'an Jiaotong UniversityXi'an, Shaanxi 710049, Peoples Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar X.-D. Liu X.-D. Liu Electronic and Information Engineering School, Xi'an Jiaotong UniversityXi'an, Shaanxi 710049, Peoples Republic of China Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Electron Microscopy, Volume 47, Issue 1, 1998, Pages 1–7, https://doi.org/10.1093/oxfordjournals.jmicro.a023554 Published: 01 January 1998 Article history Received: 29 May 1997 Accepted: 22 September 1997 Published: 01 January 1998