gebhart/patrepeval huggingface dataset:
Neural Network Applications in Control (1995)

The aim is to present an introduction to, and an overview of, the present state of neural network research and development, with an emphasis on control systems application studies. The book is useful to a range of levels of reader. The earlier chapters introduce the more popular networks and the fundamental control principles, these are followed by a series of application studies, most of which are industrially based, and the book concludes with a consideration of some recent research.
Untersuchung der Papille und Nervenfaserschicht beim Glaukom (1999)

Knowledge of all signs of the glaucomatous optic disc and forms of nerve fiber layer atrophy allows an earlier diagnosis of glaucoma and an earlier recognition of progression.
Resorbable Fixation in Facial Plastic and Head and Neck Reconstructive Surgery: An Initial Report on Polylactic Acid Implants (2001)

We found the PLA system to be highly effective, and noted no absolute contraindications to its use compared with standard metal plating systems. The 11% incidence of complications in this series was acceptable and probably not the result of the PLA implant material, although further experience is needed to determine the role of PLA implants in radiated tissue. The primary advantages to PLA appear to be its ease of use, radiolucency, eventual resorption, and, possibly, improved precision of reduction. The use in protected bone regeneration may also be an advantage, but long-term follow-up of our population will be needed to determine this. Based on short-term outcome analysis of our initial experience with PLA implantation, it appears to be an efficacious and safe technology for applications in head and neck and facial plastic surgery.
TTS based very low bit rate speech coder (1999)

This paper addresses a speech coder which uses a text-to-speech (TTS) synthesis system to achieve very low bit rates (sub 1 kbps). The main issue of the work is the accurate coding of the pitch (f/sub 0/) and gain contours which are principle components of prosody. This is of paramount interest since the correct prosody will increase naturalness and an efficient coding scheme will provide high coding gain. Together with the phonetic transcription, the f/sub 0/ and gain contour constitute the parameters that are necessary for the TTS system to synthesize the speech signal. Piecewise linear approximation is used to code the f/sub 0/ parameter. A technique which minimizes the bit rate while maintaining f/sub 0/ error below a given threshold are described. To obtain both high compression and smoothly changing gain contours, the variance of the signal is averaged over each half phoneme length is transmitted as gain information. With single speaker stimuli, and a priori text transcription information, we obtained natural sounding speech at an average bit rate of about 300 bps.
Monoclonal antibodies that detect differentiation surface antigens on human myelomonocytic cells (1982)

We describe here the production and characterization of several new monoclonal antibodies that recognize differentiation antigens present on human cells of the myelomonocytic lineage. The lineage and the stage specificities of our reagents (myeloid-, monocytic-, and myelomonocytic-specific) were determined on the basis of their reactivity with human cell lines and with human peripheral blood and bone marrow cells. Cross-competition experiments demonstrated that some of the antibodies react with the same or closely associated antigenic determinants. Five antigens have been identified in this way: one present on myeloid, one on monocytic, and three on both myeloid and monocytic cells. The possible relationship of our antibodies with other established monoclonal antibodies is discussed, in addition to their use in the in vitro study of the differentiation pathways of human hemopoietic cells and in the characterization of leukemias.
How to complete performance graphs in content-based image retrieval: add generality and normalize scope (2005)

The performance of a Content-Based Image Retrieval (CBIR) system, presented in the form of Precision-Recall or Precision-Scope graphs, offers an incomplete overview of the system under study: The influence of the irrelevant items (embedding) is obscured. In this paper, we propose a comprehensive and well-normalized description of the ranking performance compared to the performance of an Ideal Retrieval System defined by ground-truth for a large number of predefined queries. We advocate normalization with respect to relevant class size and restriction to specific normalized scope values (the number of retrieved items). We also propose new three and two-dimensional performance graphs for total recall studies in a range of embeddings.
Targeting blood-brain-barrier transcytosis – perspectives for drug delivery (2016)

Efficient transcytosis across the blood-brain-barrier (BBB) is an important strategy for accessing drug targets within the central nervous system (CNS). Despite extensive research the number of studies reporting successful delivery of macromolecules or macromolecular complexes to the CNS has remained very low. In order to expand current research it is important to know which receptors are selective and abundant on the BBB so that novel CNS-targeting antibodies or other ligands could be developed, targeting those receptors for transcytosis. To do that, we have set up a proteomics- and transcriptomics-based workflow within the COMPACT project (Collaboration on the Optimization of Macromolecular Pharmaceutical Access to Cellular Targets) of the Innovative Medicines Initiative (IMI) of the EU. Here we summarise our overall strategy in endothelial transcytosis research, describe in detail the related challenges, and discuss future perspectives of these studies. This article is part of the Special Issue entitled "Beyond small molecules for neurological disorders".
A case of a hepatitis B infected practitioner. (1993)

The first case of a dental practitioner infected by a blood-borne pathogen to be identified to the College of Dental Surgeons of B.C. and reviewed by the Dental Profession Advisory Program's infected practitioner program committee is reported. After the committee was contacted, the infected practitioner's status was evaluated and guidelines were provided to him. This paper reviews the committee's decision-making process, particularly with respect to its management of the infected dental practitioner.
Chemical Modification of Chitosan. 14: Synthesis of Water-Soluble Chitosan Derivatives by Simple Acetylation (2002)

ADVERTISEMENT RETURN TO ISSUEPREVNoteChemical Modification of Chitosan. 14: 1 Synthesis of Water-Soluble Chitosan Derivatives by Simple AcetylationHitoshi Sashiwa, Norioki Kawasaki, Atsuyoshi Nakayama, Einosuke Muraki, Noboru Yamamoto, and Sei-ichi AibaView Author Information Green Biotechnology Research Group, The Special Division for Human Life Technology, National Institute of Advanced Industrial Science and Technology, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan Cite this: Biomacromolecules 2002, 3, 5, 1126–1128Publication Date (Web):July 18, 2002Publication History Received23 April 2002Revised17 June 2002Published online18 July 2002Published inissue 1 September 2002https://pubs.acs.org/doi/10.1021/bm0200480https://doi.org/10.1021/bm0200480brief-reportACS PublicationsCopyright © 2002 American Chemical SocietyRequest reuse permissionsArticle Views2948Altmetric-Citations147LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Biodegradation,Biomaterials,Biopolymers,Chemical reactions,Reaction products Get e-Alerts
PROBLEMES RENCONTRES LORS DE L'ETUDE ET DE LA MISE AU POINT DES SUSPENSIONS MOTEURS SUR LES VEHICULES AUTOMOBILES (1980)

CONFERENCE EXTRAITE DES JOURNEES D'ETUDES ORGANISEES PAR LA 2E SECTION TECHNIQUE SIA MECANIQUE ET STRUCTURE (DIRR 110631). LORS DE LA MISE AU POINT DE VEHICULES RECEMMENT MIS SUR LE MARCHE, L'ACCENT A ETE PARTICULIEREMENT MIS SUR L'OBTENTION D'UN CONFORT VIBRATOIRE ET ACOUSTIQUE ACCEPTABLE. POSE EN CES TERMES, LE PROBLEME DE LA SUSPENSION DU GROUPE MOTOPROPULSEUR (GMP) REVET UNE IMPORTANCE NON NEGLIGEABLE DU FAIT QUE LA MASSE DU GMP REPRESENTE ENVIRON 30% DE LA MASSE SUSPENDUE PAR LE TRAIN AV SUR CES VEHICULES. CETTE MASSE EST ACCROCHEE A UNE CARROSSERIE REALISEE EN TOLE SOUDEE, AYANT AUX POINTS DE RACCORDEMENT UNE RIGIDITE NON INFINIE ; LE PROBLEME TRADUIT EN DONNEES TECHNIQUES PRESENTE DES ASPECTS ASSEZ OMPLEXES QUE L'AUTEUR EXAMINE RAPIDEMENT. LES ORGANES DE LIAISON ONT DES FONCTIONS MULTIPLES, QU'IL ESSAIERA DE CLASSER. L'AUTEUR SE PENCHE SUR LES ASPECTS VIBRATOIRES ET PHONIQUES. IL INDIQUE LES AMELIORATIONS A APPORTER AUX TASSEAUX MOTEURS QUI PRESENTAIENT JUSQU'ICI DES INSUFFISANCES.
Energy, nutrient intake and prostate cancer risk: a population-based case-control study in Sweden (1996)

The role of diet in the etiology of prostate cancer remains unclear, because results from several case-control and cohort studies on fat intake and risk of prostate cancer have been inconsistent; few of the studies have adjusted the results for caloric intake. To examine the relationship between energy, intake of several nutrients and risk of prostate cancer (all stages combined and advanced stages separately), we conducted a population-based case-control study in Orebro County, Sweden, from 1989 through 1994. A total of 526 patients with newly diagnosed prostate cancer and 536 controls, randomly selected from the population register and frequency-matched by age, were included in the analyses. Information about dietary intake was obtained from a self-administered semi-quantitative food frequency questionnaire. Odds ratios with 95% confidence intervals were estimated by unconditional logistic regression. In age-adjusted analyses, there were positive associations of prostate cancer (all stages combined) risk with total energy intake as well as intake of total fat (saturated and monounsaturated), protein, retinol and zinc. The positive association with energy intake was stronger for advanced cancer, with an excess risk of 70% for the highest quartile vs. the lowest. After adjustment for energy intake, there was no apparent association of prostate cancers (all stages combined) with any of the investigated nutrients. However, a weak positive association between intake of retinol and advanced cancer was observed. We conclude that our results provide some evidence that total energy intake is a risk factor for prostate cancer.
Importance of Reservoir Description in Evaluating in situ Recovery Methods for Cold Lake Heavy Oil: Part 2 -- in situ Application (1977)

ABSTRACT The huge reserves of heavy oil in Alberta are found in a variety of complex reservoirs. Recovery, excluding mining, will require application of some form of in situ recovery method, primarily in the better reservoirs. The proper selection of an in situ method, applicable to the various reservoir types, requires a basic understanding of reservoir description and the engineering aspect of the reservoirs. In Part 1 of this paper, reservoir description in the Cold Lake heavy-oil deposits is discussed under three headings: 1) Rock Properties, 2) Fluid Saturation, 3) Reservoir Geometry. Based on these parameters, five selected reservoir types are discussed and compared. Part 2 considers the application of the reservoir description in evaluating in situ methods. The significance of the reservoir parameters is discussed in general terms and related to the four most important in situ recovery mechanisms: steam stimulation, steam drive, combustion and solvent. The reservoir description is then used as the basis of comparison of the recovery mechanisms for each of the five Cold Lake reservoir types described in Part 1.
The effect of weak chelating agents on the removal of heavy metals by precipitation processes (1986)

Abstract Particle size distributions and heavy metal removals are presented for hydroxide precipitations and heavy metal removals are presented for hydroxide precipitation and sulfide precipitation of zinc and cadmium in the presence of several weak complexing agents, namely citrate, tartrate, and ammonia. The pH was held constant at pH 10.0 in these experiments. The presence of these weak complexing agents had little effect on the chemical equilibrium for both the hydroxide and sulfide systems due to their weak complexing ability with metal ions. The presence of the complexing agents does affect the particle size distribution, generally forming smaller particles. Particle size distributions are presented for the Zn(OH) 2 , ZnS, Cd(OH) 2 , and CdS systems (at pH 10.0) in the presence of the chelating agents citrate, tartrate, and ammonia. Sulfide precipitation exhibits a better particle size distribution and settling characteristics than the corresponding metal hydroxide precipitation for both zinc and cadmium.
Ligation of Major Histocompatability Complex (MHC) Class I Molecules on Human T Cells Induces Cell Death through PI-3 Kinase–induced c-Jun NH2-terminal Kinase Activity: A Novel Apoptotic Pathway Distinct from Fas-induced Apoptosis (1997)

Ligation of major histocompatability complex class I (MHC-I) molecules expressed on T cells leads to both growth arrest and apoptosis. The aim of the current study was to investigate the intracellular signal pathways that mediate these effects. MHC-I ligation of human Jurkat T cells induced a morphologically distinct form of apoptosis within 6 h. A specific caspase inhibitor, which inhibited Fas-induced apoptosis, did not affect apoptosis induced by MHC-I ligation. Furthermore, MHC-I-induced apoptosis did not involve cleavage and activation of the poly(ADP- ribose) polymerase (PARP) endonuclease or degradation of genomic DNA into the typical fragmentation ladder, both prominent events of Fas-induced apoptosis. These results suggest that MHC-I ligation of Jurkat T cells induce apoptosis through a signal pathway distinct from the Fas molecule. In our search for other signal pathways leading to apoptosis, we found that the regulatory 85-kD subunit of the phosphoinositide-3 kinase (PI-3) kinase was tyrosine phosphorylated after ligation of MHC-I and the PI-3 kinase inhibitor wortmannin selectively blocked MHC-I-, but not Fas-induced, apoptosis. As the c-Jun NH2-terminal kinase (JNK) can be activated by PI-3 kinase activity, and has been shown to be involved in apoptosis of lymphocytes, we examined JNK activation after MHC-I ligation. Strong JNK activity was observed after MHC-I ligation and the activity was completely blocked by wortmannin. Inhibition of JNK activity, by transfecting cells with a dominant-negative JNKK- MKK4 construct, led to a strong reduction of apoptosis after MHC-I ligation. These results suggest a critical engagement of PI-3 kinase-induced JNK activity in apoptosis induced by MHC-I ligation.
Indigenous and enhanced mineralization of pyrene, benzo[a]pyrene, and carbazole in soils (1991)

We studied the mineralization of pyrene, carbazole, and benzo[a]pyrene in soils obtained from three abandoned coal gasification plants in southern Illinois. The soils had different histories of past exposure to hydrocarbon contamination and different amounts of total organic carbon, microbial biomass, and microbial activity. Mineralization was measured by using serum bottle radiorespirometry. The levels of indigenous mineralization of 14C-labeled compounds ranged from 10 to 48% for pyrene, from undetectable to 46% for carbazole, and from undetectable to 25% for benzo[a]pyrene following long-term (greater than 180-day) incubations. Pyrene and carbazole were degraded with short or no lag periods in all soils, but benzo[a]pyrene mineralization occurred after a 28-day lag period. Mineralization was not dependent on high levels of microbial biomass and activity in the soils. Bacterial cultures that were capable of degrading pyrene and carbazole were isolated by enrichment, grown in pure culture, and reintroduced into soils. Reintroduction of a pyrene-degrading bacterium enhanced mineralization to a level of 55% within 2 days, compared with a level of 1% for the indigenous population. The carbazole degrader enhanced mineralization to a level of 45% after 7 days in a soil that showed little indigenous carbazole mineralization. The pyrene and carbazole degraders which we isolated were identified as a Mycobacterium sp. and a Xanthamonas sp., respectively. Our results indicated that mineralization of aromatic hydrocarbons can be significantly enhanced by reintroducing isolated polycyclic aromatic hydrocarbon-degrading bacteria.
Genome Mining for Novel Natural Product Discovery (2008)

ADVERTISEMENT RETURN TO ISSUEPREVPerspectiveNEXTGenome Mining for Novel Natural Product DiscoveryGregory L. Challis†View Author Information Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.†Contact information. Phone: +44 (0) 2476 574024. Fax: +44 (0) 2476 524112. E-mail: [email protected].Cite this: J. Med. Chem. 2008, 51, 9, 2618–2628Publication Date (Web):April 5, 2008Publication History Received1 August 2007Published online5 April 2008Published inissue 1 May 2008https://pubs.acs.org/doi/10.1021/jm700948zhttps://doi.org/10.1021/jm700948zreview-articleACS PublicationsCopyright © 2008 American Chemical SocietyRequest reuse permissionsArticle Views6556Altmetric-Citations180LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cluster chemistry,Genomics,Metabolism,Peptides and proteins,Pharmaceuticals Get e-Alerts
Circuit performance of CMOS technologies with silicon dioxide and reoxidized nitrided oxide gate dielectrics (1990)

The circuit performance of CMOS technologies with silicon dioxide (SiO/sub 2/) and reoxidized nitrided oxide (RONO) gate dielectrics over the normal regime of digital circuit operation, i.e. V/sub GS/<or=5 V and B/sub DS/<or=5 V, is discussed. The simulation of a simple CMOS inverter has shown that the SiO/sub 2/ inverter consistently outperforms the RONO inverter over temperatures ranging from 300 to 100 K. This can be attributed mainly to the significantly lower mu /sub p/ (hole mobility) of RONO p-channel devices. At 300 K, mu /sub p/(RONO) is 14-8% smaller than mu /sub p/(SiO/sub 2/) over the entire range of gate biases, while mu /sub n/(RONO) (electron mobility of n-channel RONO devices) is also smaller than mu /sub n/(SiO/sub 2/) and reaches only 96% of mu /sub n/(SiO/sub 2/) at V/sub GS/=5 V. At 100 K, mu /sub n/(RONO)/ mu /sub n/(SiO/sub 2/) at V/sub GS/=5 V is increased to 1.10, however, mu /sub p/(RONO)/ mu /sub p/(SiO/sub 2/) at V/sub GS/=5 V is degraded to 0.59. The dependence of circuit performance on the supply voltage has also been evaluated for the RONO and SiO/sub 2/ inverters.<<ETX>>
Gigabit Ethernet backbones with active loops (2001)

The current standard Ethernet switches are based on the Spanning Tree (ST) protocol. Their most important restriction is that they can not work when the topology has active loops. In fact, the ST protocol selects a tree from the real topology by blocking the links that are not involved in the tree. This restriction produces a network traffic unbalancing behavior saturating those link near the root switch while rest of links will be idle or with a very low utilization. This paper proposes a new transparent switch protocol for Gigabit Ethernet backbones that considerably improves the performance of current ones. The proposed protocol is named ALOR for Active Loops and Optimal Routing. ALOR protocol could be used in the last stage of a fat tree network in order to allow a final backbone with active loops. So, rings, mesh and other regular/irregular active loop topologies can be used to connect the Gigabit switches in order to obtain better performance results.
Calcification in Major Vessel Beds Relates to Vascular Brain Disease (2011)

Arterial calcification in major vessel beds is associated with vascular brain disease on magnetic resonance imaging. Most notably, larger intracranial carotid calcification load relates to larger WML volumes, and larger extracranial carotid calcification load relates to the presence of cerebral infarcts, independently of ultrasound carotid plaque score. This suggests that calcification of atherosclerotic plaque yields other information in addition to merely the presence of plaques, providing novel insights into the etiology of vascular brain disease.
Aerosol direct fluorination of C1 and C2 chlorocarbons (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAerosol direct fluorination of C1 and C2 chlorocarbonsJames L. Adcock, Sastry A. Kunda, Donald R. Taylor, Mario J. Nappa, and Allen C. SievertCite this: Ind. Eng. Chem. Res. 1989, 28, 10, 1547–1549Publication Date (Print):October 1, 1989Publication History Published online1 May 2002Published inissue 1 October 1989https://pubs.acs.org/doi/10.1021/ie00094a019https://doi.org/10.1021/ie00094a019research-articleACS PublicationsRequest reuse permissionsArticle Views179Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts