gebhart/patrepeval huggingface dataset:
Carbonylation of platinum and palladium organo-complexes (1966)

Acyl derivatives of the type trans-[MX(COR)(PEt3)2](M = Pt or Pd; X = Cl, Br, or I; R = Me, Et, or Ph) have been prepared by the action of carbon monoxide on alkyl and aryl derivatives of the type [MXR(PEt3)2]. Carbon monoxide reacts with the complex cis-[PtMe2(PEt3)2] to give a novel carbonyl complex [Pt3(CO)n(PEt3)4](n= 3 or 4) and biacetyl. Other related disubstituted derivatives gave either unstable or intractable products. Some alkyl and aryl platinum and palladium derivatives were too unstable to be carbonylated, or gave carbonylated products too unstable to isolate.
Wrapper design for testing IP cores with multiple clock domains (2004)

This paper addresses the testability problems raised by embedded cores with multiple clock domains. The proposed solution, based on a novel core wrapper architecture, shows how multi-frequency at-speed test response capture can be achieved using low-speed testers synchronized with high-speed on-chip generated clocks. Using experimental data, the trade-offs between the number of tester channels, testing time, area overhead and power dissipation are discussed.
Reading Elaine: Marjorie Richardson's and L. M. Montgomery's Red-Haired Lily Maids (2007)

Marjorie Richardson's story "Launcelot's Tower" and L. M. Montgomery's novel Anne of Green Gables have child characters who read, imitate, and rewrite Arthurian pre-texts; Richardson's Susan Briggs and Montgomery's Anne Shirley imitate Elaine of Astolat and thus certain conventions of appropriate feminine behavior, but because they then reject Elaine as an icon of femininity, these authors raise questions about women's roles in traditional romance narratives. Richardson's and Montgomery's texts thus demonstrate the potential of "reading" as a critical and imaginative activity; they suggest the power of readers—even child readers—to construct meaningful self-narratives.
Review: Cardioprotective effects of telmisartan in uncomplicated and complicated hypertension (2008)

The development of angiotensin II receptor blockers (ARB) as a new class of drugs for the management of hypertension has elicited the attention of many clinicians worldwide with the aim of improving blood pressure (BP) control as well as cardiovascular protection. Among ARB telmisartan has been shown to be characterised by an antihypertensive efficacy fully covering the 24-hour period, thereby allowing to antagonise the adverse effects of early morning BP rise on cardiovascular risk. Other specific effects of the drug are represented by its favourable metabolic profile (particularly on insulin sensitivity) and neutral effects on sympathetic cardiovascular function. These properties are coupled with cardioprotective effects, documented by the evidence that the drug: 1) is effective in favouring the regression of cardiac and vascular organ damage, 2) reduces arterial stiffness and improves vascular distensibility and 3) reverses the endothelial dysfunction typical of the hypertensive state particularly when complicated by renal failure, diabetes, obesity or metabolic syndrome. Several of these properties can account for the results of the ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial (ONTARGET), documenting the beneficial effects on the drug on cardiovascular morbidity and mortality.
Genetic Modification Strategies to Enhance CAR T Cell Persistence for Patients With Solid Tumors (2019)

Immunotherapy with chimeric antigen receptor (CAR) T cells offers a promising method to improve cure rates and decrease morbidities for patients with cancer. In this regard, CD19-specific CAR T cell therapies have achieved dramatic objective responses for a high percent of patients with CD19-positive leukemia or lymphoma. Most patients with solid tumors however, have experienced transient or no benefit from CAR T cell therapies. Novel strategies are therefore needed to improve CAR T cell function for patients with solid tumors. One obstacle for the field is limited CAR T cell persistence after infusion into patients. In this review we highlight genetic engineering strategies to improve CAR T cell persistence for enhancing antitumor activity for patients with solid tumors.
Standardized beam bouquets for lung IMRT planning (2015)

The selection of the incident angles of the treatment beams is a critical component of intensity modulated radiation therapy (IMRT) planning for lung cancer due to significant variations in tumor location, tumor size and patient anatomy. We investigate the feasibility of establishing a small set of standardized beam bouquets for planning. The set of beam bouquets were determined by learning the beam configuration features from 60 clinical lung IMRT plans designed by experienced planners. A k-medoids cluster analysis method was used to classify the beam configurations in the dataset. The appropriate number of clusters was determined by maximizing the value of average silhouette width of the classification. Once the number of clusters had been determined, the beam arrangements in each medoid of the clusters were designated as the standardized beam bouquet for the cluster. This standardized bouquet set was used to re-plan 20 cases randomly selected from the clinical database. The dosimetric quality of the plans using the beam bouquets was evaluated against the corresponding clinical plans by a paired t-test. The classification with six clusters has the largest average silhouette width value and hence would best represent the beam bouquet patterns in the dataset. The results shows that plans generated with a small number of standardized bouquets (e.g. 6) have comparable quality to that of clinical plans. These standardized beam configuration bouquets will potentially help improve plan efficiency and facilitate automated planning.
Case-Control Study of Periconceptional Folic Acid Supplementation and Oral Clefts (1996)

There is consistent evidence that the risk of neural tube defects is decreased by periconceptional supplementation with folic acid. A similar protective effect has been postulated for oral clefts. A case-control study was conducted in greater metropolitan Boston; Massachusetts; Philadelphia, Pennsylvania; and southeastern Ontario, Canada, from 1988 through 1991 to test the hypothesis that folic acid supplementation during the periconceptional period reduces the risk of oral clefts. Crude and multivariate-adjusted relative risks were calculated for all oral clefts (n = 303), cleft palate (n = 108), and cleft lip with or without cleft palate (n = 195). Controls (n = 1,167) were liveborn or stillborn infants less than age 6 months who had various congenital anomalies other than oral clefts, neural tube defects, or other "midline defects." Adjusted relative risks and 95 percent confidence intervals for daily folic acid supplementation during the periconceptional period were: oral clefts, 1.1 (95% confidence interval (CI) 0.8-1.7), cleft palate, 0.9 (95% CI 0.5-1.6), and cleft lip with or without cleft palate, 1.3 (95% CI 0.8-2.1). These findings do not support a protective association between the periconceptional use of folic acid supplements and the risk of oral clefts.
如果“云”知道——“苹果”惹的祸？ (2014)

安全与隐私的担忧一直都是云存储与云计算行业的最大挑战。iCloud是由苹果公司所提供的云存储和云计算服务，最近因为黑客入侵而崩溃了。早些时候，有报道指出是一个黑客团体操纵了这起网络犯罪活动。但是现在，据最新的网上哥伦比亚广播公司报道显示，一名黑客非法侵入了iCloud系统，窃取多位女演员的私密照片，现在这些照片正在社交媒体上被好色的名人追踪者垂涎窥视。
Evaluation of Imprint Properties in Sol-Gel Ferroelectric Pb(ZrTi)O<sub>3</sub> Thin-Film Capacitors (1993)

Studies of imprint properties have been carried out by electrical evaluation with pulse switching response and circuit modeling on sol-gel lead zirconate titanate (PZT) ferroelectric thin-film capacitors. The imprint properties were evaluated by measuring the switched and nonswitched charges after three different operations at high temperature, which consist of (1) fatigue by cumulative bipolar pulses, (2) exposure to a large number of positive unipolar pulses, and (3) exposure to a large number of negative unipolar pulses. The nonswitched charge without polarization reversal after being exposed to a large number of unipolar pulses was increased to be greater than switched charge with polarization reversal. This causes the decrease of a noise margin when the memory cell is read. This phenomenon is enhanced by the sample temperature above 75°C, the pulse height, and the amount of cumulative fatigue cycles before imprint. This phenomenon is also found in the Nb-doped PZT capacitor, which is a candidate for fatigue-free materials.
Abstract 5893: Biventricular Versus Right Ventricular Delivered Anti-Tachicardia Pacing for the Termination Of Ventricular Tachyarrhythmias in Heart Failure Patients Receiving a Biventricular ICD: Results from the ADVANCE CRT-D Trial (2008)

Aim: To investigate the efficacy and safety of anti-tachycardia pacing (ATP) simultaneously delivered from right and left ventricles (BIV) vs conventional right ventricular (RV) delivery in heart failure (HF) patients treated with a biventricular ICD (CRT-D). Methods : Multicenter, prospective, randomized, controlled trial of pts implanted with a Medtronic CRT-D device. Anti-tachycardia detections were programmed: VF detection set at NID 18/24 for ≥250 bpm; FVT (via VF) with NID 18/24 between 188–250 bpm; VT detected when 20 consecutive RR intervals ≥143 bpm. Randomization was 1:1 to either BiV or RV ATP (single burst 8 pulse, 88% coupling interval ). Pts were followed for 12 months. Stored EGM, used to classify all spontaneous episodes, as well as all adverse events (including death) were adjudicated by an independent committee adjusting for pts with multiple episodes. The primary end-point (PEP) compared the efficacy of first BiV vs RV to terminate any ventricular tachyarrhythmias (VTs). The secondary composite end-point (SEP) compared adverse events (accelerations+ syncope/pre-syncope) to assess safety. Results : In total, 526 patients were enrolled and randomized (BiV = 260, RV = 266). There were no baseline differences between groups. In total, 1077 detections in 178 patients were recorded: 634 were true VTs in 119 patients (69 VF [11%] in 18 pts, 202 FVT [32%] in 49 pts, and 363 VT [57%] in 92 pts). PEP: Efficacy of first ATP was comparable between BiV (65%) and RV (68%) (p=0.58). In VT zone, RV was better (62% vs 71%., p=0.24), while in FVT zone BIV proved better (71% vs. 61%, p=0.33). RV ATP was significantly less effective in ischemic (I) pts (81% vs 59%, p=0.005). SEP: BIV ATP was ineffective 20 times and 3 accelerations occurred, whereas RV ATP failed 41 times and 14 accelerations occurred (p=0.12). Syncope/pre-syncope events never occurred for BiV ATP, while 4 times (3%) in RV ATP(p=0.3). No difference in mortality was observed. Conclusion : This trial demonstrated that ATP is also effective in CRT-D recipients. No significant differences in overall ATP efficacy were found between BIV and RV, but RV was significantly less effective in I patients; BIV was effective across different etiologies and showed a trend for superior safety profile.
Biological Control of Fusarium moniliforme in Maize (2001)

Charles W. Bacon, Ida E. Yates, Dorothy M. Hinton, Filmore Meredith, Biological Control of Fusarium moniliforme in Maize, Environmental Health Perspectives, Vol. 109, Supplement 2 (May, 2001), pp. 325-332
Mixed-Initiative Long-Term Interactions with an All-Day-Companion Robot (2010)

As robots become incorporated into our environments, they must be equipped with the ability to communicate effectively with us. In particular, robots that perform longer tasks for a small set of people (e.g., a companion robot to escort visitors to meetings all day) need to be able to start and maintain interesting and relevant dialog with any and all humans involved. In this work, we present our ongoing work on our robot, CoBot, which is assigned an all-day task to escort a visitor around our building and perform tasks for her. We first describe CoBot’s dialog manager which is responsible for the task-oriented dialog, including dialog to meet the visitor’s needs, CoBot’s notifications of interesting locations around the building, and the robot’s own requests for help. We, then, focus two aspects of the dialog manager: 1) how CoBot can invoke more accurate answers to its requests for help from the visitor and 2) how to reduce repetitive dialog which can happen during all-day interactions. We provide an example dialog between CoBot and a visitor to illustrate the dialog manager’s capabilities.
Brainstem auditory evoked potentials for intraoperative neurophysiological monitoring (2016)

Spontaneous electrical activity of brain – electroencephalogram (EEG) – is of significant amplitude (~100 μV) and can mask the small electrical activities produced by stimulation of a specific sensory modality. The strategy to extract electrical activity produced by the auditory system alone (<1 μV) is to provide repetitive auditory stimuli and to average the resulting electrical responses recorded from the scalp, so that time-locked events alone would stand out, with cancellation of random noise, which in this case is background EEG.
Synthesis and Performance of Gel Polymer Li-Ion Batteries (2010)

Abstract not Available.
Poly[glycidyl methacrylate(GMA)/methylmethacrylate(MMA)-b-butadiene(B)-b-GMA/MMA] reactive thermoplastic elastomers: Synthesis and characterization (1997)

New block copolymers of the ABA type, where B stands for polybutadiene (PBD) and A for polyglycidylmethacrylate(PGMA), poly(methylmethacrylate(MMA)-co-GMA) and PMMA-b-PGMA, respectively, have been successfully synthesized by using the diadduct of tert-butyllithium (tert-BuLi) to meta-diisopropenylbenzene (m-DIB) as a difunctional initiator. The PBD midblock has been synthesized in a cyclohexane/diethylether (100/6, v/v) mixture at room temperature, whereas the methacrylate outer blocks have been synthesized in a cyclohexane/diethylether/THF (100/6/150, v/v/v) mixture at −78°C. Block copolymers of a very narrow molecular weight distribution (1.10) have been analyzed by differential scanning calorimetry (DSC), transmission electron microscopy (TEM), and tensile testing. These materials are phase separated and can exhibit tensile strength up to 22 MPa together with very high elongation at break (1500%). © 1997 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 35: 3507–3515, 1997
C<scp>ellular</scp>, M<scp>olecular, and</scp> G<scp>enetic</scp> D<scp>eterminants of</scp> T<scp>ooth</scp> E<scp>ruption</scp> (2002)

Tooth eruption is a complex and tightly regulated process that involves cells of the tooth organ and the surrounding alveolus. Mononuclear cells (osteoclast precursors) must be recruited into the dental follicle prior to the onset of eruption. These cells, in turn, fuse to form osteoclasts that resorb alveolar bone, forming an eruption pathway for the tooth to exit its bony crypt. Some of the molecules possibly involved in the signaling cascades of eruption have been proposed in studies from null mice, osteopetrotic rodents, injections of putative eruption molecules, and cultured dental follicle cells. In particular, recruitment of the mononuclear cells to the follicle may require colony-stimulating factor-one (CSF-1) and/or monocyte chemotactic protein-1 (MCP-1). Osteoclastogenesis is needed for the bone resorption and may involve inhibition of osteoprotegerin transcription and synthesis in the follicle, as well as enhancement of receptor activator of NF kappa B ligand (RANKL), in the adjacent alveolar bone and/or in the follicle. Paracrine signaling by parathyroid-hormone-related protein and interleukin -1 alpha, produced in the stellate reticulum adjacent to the follicle, may also play a role in regulating eruption. Osteoblasts might also influence the process of eruption, the most important physiologic role likely being at the eruptive site, in the formation of osteoclasts through signaling via the RANKL/OPG pathway. Evidence thus far supports a role for an osteoblast-specific transcription factor, Cbfa1 (Runx2), in molecular events that regulate tooth eruption. Cbfa1 is also expressed at high levels by the dental follicle cells. This review concludes with a discussion of the several human conditions that result in a failure of or delay in tooth eruption.
Cells and tissue imaging with digital holographic microscopy (2003)

The aim of Optical Digital Holography, applied to cells and tissue imaging, is to provide an accurate 3D imaging of biologic materials, down to the microscopic scale. The method has been developed to yield a very precise determination of cells and tissues morphology. Targeted accuracies are in the sub-micron range and allow for the observation of very small movements and deformations, produced, in particular, by depolarization of excitable cells and their metabolic activities. Direct imaging of tissue structures by the newly developed digital holography is deemed to offer unique investigation means in biology and medicine and attractive diagnostic capabilities.
Transitivity (2008)

Transitivity is formally just a property that a binary relation might possess, and thus one could discuss the concept in any context in economics in which an ordering relation is used. Here, however, the discussion of transitivity will be limited to its role in describing an individual agent’s choice behaviour. In this context transitivity means roughly that if an agent chooses A over B, and B over C, that agent ought to choose A over C, or at least be indifferent. On the surface this seems reasonable, even ‘rational’, but this ignores how complicated an agent’s decision making process can be. For an excellent discussion of this issue see May (1954). Given a model of agent behaviour, transitivity can be imposed as a direct assumption, or can be an implication of the model for choice behaviour. The standard model of agent behaviour in economics is that the agent orders prospects by means of a utility function, which in effect assumes transitivity. With appropriate continuity and convexity restrictions on utility functions, the model allows one to demonstrate that: (1) Individual demand functions are well defined, continuous, and satisfy the comparative static restriction, the strong axiom of revealed preference (SARP). (In the smooth case, this corresponds to the negative semi-definiteness and symmetry of the Slutsky matrix.) (2) Given a finite collection of such agents with initial endowments of goods, a competitive equilibrium exists. What will be discussed in the remaining part of this article is to what extent one can obtain results analogous to (1) and (2) above while using a model of agent behaviour which does not assume or imply transitive behaviour. To keep the discussion as simple as possible, we will only consider the situation in which the agent’s set of feasible commodity vectors is the non-negative orthant of n-dimensional Euclidean space, and the agent’s problem is to choose a commodity vector x when faced with positive prices and income. A vector p in the positive orthant of Euclidean n-space will denote the vector of price-income ratios, or a ‘price’ system.
USING EVENT NOTIFICATION SERVERS TO SUPPORT APPLICATION AWARENESS (2002)

In previous work, we presented a software strategy called CASS (Cross Application Subscription Service) and an accompanying event notification server called CASSIUS (CASS Information Update Server) for supporting awareness. Roughly, awareness refers to the ability to have available, pertinent information about other activities, usually the activities of co-workers. Ongoing work raised the question of how essential the CASSIUS server was to our overall goal of supporting awareness. This present work examines that question through a twofold evaluation (theoretical and practical) of CASSIUS and the event notification servers Elvin and Siena, which are more readily available than CASSIUS. Together, these servers represent a gamut of services, from basic to extended, available among notification servers. Our interest and approach to evaluating the three servers has been very practical. We are concerned with how the services provided make the servers usable to application designers and programmers.
Inter-sentence Relation Extraction with Document-level Graph Convolutional Neural Network (2019)

Inter-sentence relation extraction deals with a number of complex semantic relationships in documents, which require local, non-local, syntactic and semantic dependencies. Existing methods do not fully exploit such dependencies. We present a novel inter-sentence relation extraction model that builds a labelled edge graph convolutional neural network model on a document-level graph. The graph is constructed using various inter-and intra-sentence dependencies to capture local and non-local dependency information. In order to predict the relation of an entity pair, we utilise multi-instance learning with bi-affine pairwise scoring. Experimental results show that our model achieves comparable performance to the state-of-the-art neural models on two biochemistry datasets. Our analysis shows that all the types in the graph are effective for inter-sentence relation extraction.
Optical seizing and merging of voids in silica glass with infrared femtosecond laser pulses (2000)

We demonstrate that one can seize and translate voids formed by IR femtosecond laser pulses inside silica glass and can also cause two voids to merge into one. We also present clear evidence of a void and its surrounding region by showing scanning electron microscope images of cleaved voids, which we produced by cleaving through the glass along a plane that included a thin laser-ablated line on the surface of the glass and the voids formed inside.
RobotUI - A software architecture for modular robotics user interface frameworks (2012)

Modern robotics frameworks are based on modular architectures that enable them to cope with the complexity and diversity of today's robotics applications. The encapsulation of the framework modules is the key to their reuse in various robotics scenarios. Model-driven approaches further simplify the reuse of already implemented and tested modules by enabling developers to model their applications on a higher abstraction level incorporating existing modules [1]. Unfortunately, these features are only present for the implementation of the robot behavior itself, but not for the accompanying user interfaces (UIs). The contributions of this paper are threefold: In a first step we introduce the idea of dedicated robotics UI frameworks which allow the reuse of UIs across robotics frameworks. The paper then presents an architecture for flexible and versatile UI frameworks for robotics applications by investigating and specifying the necessary features for such systems on a platform and programming language independent basis. The introduced ROBOTUI architecture fosters code reuse on the level of self-contained UI modules and enables the user to build new robotics related UIs based on existing UI building blocks. Finally, we present an implementation of the proposed architecture that demonstrates the advantages of a dedicated UI framework and the high level of code reuse achieved by implementing the modular ROBOTUI architecture.
Digital interpolating peak locator (2016)

Locating the position of the peak of an analog signal after it has been sampled is a challenging task with wide-ranging applications. The conventional methods of performing this operation involve either upsampling the digital signal or fitting a parabolic curve to the digital samples. This paper proposes a technique for finding the approximate location of the peak in an analog signal after it has been sampled. The technique involves transforming the sampled data into the logarithm domain and then fitting a parameterized function that is characteristic of the analog signal to the two points neighbouring the peak. The location of the peak is calculated from the parameters obtained in the fitting process. Simulation results show that the proposed estimator significantly outperforms the conventional estimators at a comparable or lower hardware cost.