gebhart/patrepeval huggingface dataset:
Flash storage integration in the IBM System z EC12 I/O drawer (2013)

Flash storage is integrated for the first time on System z® as a card in the EC12 I/O drawer. This provides a number of functions and benefits in the immediate product, in addition to laying a foundation for further system benefits in future generations of System z systems. Enabling flash MLC (multilevel cell) technology as SCM (storage class memory) in an enterprise-class product required myriad diverse individual technological advances, together with a series of system design features. Extreme care and attention were paid to ensure that the required level of System z reliability was maintained. As with legacy I/O, the programming interface is subchannel-based. The subchannel programming interface is expanded with new architecture via the extended asynchronous-data-move facility. Operating system changes were required to enable exploitation of the features that this new system technology offers. These individual hardware, firmware, and software design aspects are described in this paper, along with the overall functionality and system-level value of this new technology.
Pyrimidine and Its <i>C</i> ‐Alkyl and <i>C</i> ‐Aryl Derivatives ( <i>H</i> 116) (1970)

This chapter contains sections titled: Pyrimidine (Unsubstituted) (H 116) C-Alkyl and C-Aryl Pyrimidines (H 119)
The importance of investing in agriculture : securing our future (2017)

Food makes the world go around and for the world to have sufficient food to eat, producers need to continue investing in agriculture. This will enable the sector to grow and will contribute to food security. Food production is a business like any other and it needs to show profit in order for producers to invest funds in agriculture each year. In South Africa, investment in agriculture has drastically declined over the past few years. This trend not only threatens the country’s food security, but it also limits the potential of the local agricultural sector to grow. If investment in agriculture is not restored, it could have dire consequences for the food security of future generations as well as the industry.
VIM-19, a Metallo-β-Lactamase with Increased Carbapenemase Activity from <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> (2009)

Two carbapenem-resistant isolates, one Escherichia coli isolate and one Klebsiella pneumoniae isolate, recovered from an Algerian patient expressed a novel VIM-type metallo-beta-lactamase (MBL). The identified bla(VIM-19) gene was located on a ca. 160-kb plasmid and located inside a class 1 integron in both isolates. VIM-19 differed from VIM-1 by the Asn215Lys and Ser228Arg substitutions, increasing its hydrolytic activity toward carbapenems. Site-directed mutagenesis experiments showed that both substitutions were necessary for the increased carbapenemase activity of VIM-19. This study indicates that MBLs with enhanced activity toward carbapenems may be obtained as a result of very few amino acid substitutions.
International Fungicide Efficacy Trials for the Management of Soybean Rust (2007)

The efficacy of fungicides in managing soybean rust was evaluated in 12 environments in South America and southern Africa over three growing seasons from 2002 to 2005. There were differences in final soybean rust severity, defoliation, and yield among the treatments at most locations. In locations where soybean rust was not severe, all the fungicides evaluated reduced severity. In locations where soybean rust was severe, applications of triazole and triazole + strobilurin fungicides resulted in lower severity and higher yields compared with other fungicides. The strobilurin fungicides provided the highest yields in many locations; however, severity tended to be higher than that of the triazole fungicides. There also were differences in yield and severity between the trials with two and three applications of several fungicides, with three applications resulting in less severe soybean rust and higher yields. However, the third application of tebuconazole, tetraconazole, and the mixtures containing azoxystrobin and pyraclostrobin was not needed to maintain yield. These fungicides were among the most effective for managing soybean rust and maintaining yield over most locations.
A Histopathologic Investigation on the Effects of Electrical Stimulation on Periodontal Tissue Regeneration in Experimental Bony Defects in Dogs (2005)

This study demonstrated that the CCEF method has the potential to produce reconstructive effects and bone deposits. Further investigations with respect to the theoretical determination of local field parameters of the periodontal tissue complex, such as permittivity, conductivity, strength of the field electrical stimulation applied to the periodontal field current density, wavelength, and signal frequency appropriate for this field, should be undertaken. Using different electromotive forces alone or in combination with bone graft materials, guided tissue regeneration techniques, and dental implants may achieve a new dimension in periodontal therapy in the near future.
Traitements et revêtements de surface à usage tribologique (2011)

En cours de fonctionnement, les surfaces des composants mécaniques sont soumises à des sollicitations de type mécanique, thermique et physicochimique. Pour les composants à fonctions tribologiques, à ces sollicitations s'ajoutent celles générées par les actions de contact, ce qui impose alors des propriétés des couches superficielles supérieures à celles requises pour les matériaux en volume. Les traitements et les revêtements de surface, choisis en fonction des risques majeurs d’endommagement (abrasion, adhésion, érosion…), peuvent apporter aux surfaces une résistance mécanique ou physico-chimique adaptée, sans nécessité à cœur de matériaux onéreux. De nos jours, les avancées technologiques permettent d’offrir un grand choix de possibilités de traitements et de revêtements de surface à usage tribologique.
Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons (2002)

In dystrophic mice, a model of merosin-deficient congenital muscular dystrophy, laminin-2 mutations produce peripheral nerve dysmyelination and render Schwann cells unable to sort bundles of axons. The laminin receptor and the mechanism through which dysmyelination and impaired sorting occur are unknown. We describe mice in which Schwann cell-specific disruption of beta1 integrin, a component of laminin receptors, causes a severe neuropathy with impaired radial sorting of axons. beta 1-null Schwann cells populate nerves, proliferate, and survive normally, but do not extend or maintain normal processes around axons. Interestingly, some Schwann cells surpass this problem to form normal myelin, possibly due to the presence of other laminin receptors such as dystroglycan and alpha 6 beta 4 integrin. These data suggest that beta 1 integrin links laminin in the basal lamina to the cytoskeleton in order for Schwann cells to ensheath axons, and alteration of this linkage contributes to the peripheral neuropathy of congenital muscular dystrophy.
Changes in cell surface glycoproteins during <i>Dictyostelium</i> development analysed using monoclonal antibodies (1989)

We have produced a series of monoclonal antibodies that recognize carbohydrate epitopes on cell surface glycoproteins of developing amoebae of Dictyostelium discoideum. The antibodies were found to have differential specificity for amoebae at different stages of development and were classified into types A to E on the basis of their temporal pattern of reactivity with the developing amoebal cell surface. Evidence from Western Blots and digestion of the glycoproteins with alkaline phosphatase were consistent with previous reports that the cell surface glycoproteins are extensively processed during development, leading at 16 h of development to the exposure of a highly antigenic core recognized by antibodies in group E. The nature of this core structure is indicated by the finding that antibodies in group E were found also to bind with high avidity to the plant glycoprotein horse radish peroxidase.
Tailored Doxorubicin‐<scp>H</scp>yaluronan Conjugate as a Potent Anticancer Glyco‐<scp>D</scp>rug: An Alternative to Prodrug Approach (2013)

Releasibility of doxorubicin from drug-conjugates is believed to be a prerequisite for its anti-cancer activity. Here, a new glyco-drug approach that circumvents the releasibility restriction is reported, opening a new possibility to design efficient, target specific drug delivery system. It is discovered that stable amide coupling of doxorubicin (DOX) tohyaluronan (HA) shows dose dependent cytotoxicity to CD44 positive human coloncancer cells (HCT116) as compared to human breast cancer cells(MCF-7) and mouse fibroblast cells (NIH-3T3), which express less CD44 receptor. This direct conjugation approach is an easy scalable strategy that could be adopted to design innocuous anti-tumor nanoparticle formulations.
Making agents secure on the semantic Web (2002)

Agents were designed to collaborate and share information. While highly desirable for interoperability, this feature is scary from the security perspective. Illegal inferences, supported by semantic Web technology and ontologies, might enable users to access unauthorized information. In addition to semantic associations and replicated data with different sensitivity, malicious agents could also exploit statistical inferences. Although each agent in a system might behave in a desired and secure way, their combined knowledge could be used to disclose sensitive data. The research community must therefore develop and implement techniques that allow control over released data. To answer the questions related to information availability (scalability), data correctness (integrity), and access control in the presence of illegal inferences and undesired collaborations (confidentiality), researchers in semantic Web technologies (XML, RDF, DAML, and multiagent systems) and information system security need to collaborate. Indeed, given the Web's openness, dynamic nature, and diverse user population, developing secure Web services will require the collaboration of experts in different fields from both industry and academia. In turn, the intelligent Web of the future will facilitate unheard of support for collaborations and information management.
Purification, characterization, and expression of rat epididymal β‐D‐galactosidase (1997)

The purpose of the present study is to purify, kinetically characterize and measure the amount of soluble acid beta-D-galactosidase (EC 3.2.1.23) in different anatomical regions (caput, corpus, and cauda) of the adult rat epididymis. Based upon SDS-PAGE analysis, the subunit molecular mass of the caput and cauda enzyme is approximately 85,000 daltons while the corpus enzyme is approximately 50,000 daltons. The apparent Km and Vmax values are 67, 24, and 59 microM and 5.0, 1.88 and 6.3 microM/min./-mg protein for the enzyme purified from the caput, corpus, and cauda regions of the epididymis, respectively. However, no regional differences in the amount of soluble enzyme protein are observed. These data demonstrates regional differences in the activity of epididymal acid beta-D-galactosidase and suggest that the observed regional differences in enzyme activity may be due to posttranslational modifications.
Mechanism of stimulation of DNA replication by bacteriophage phi 29 single-stranded DNA-binding protein p5 (1991)

Protein p5 is a Bacillus subtilis phage phi 29-encoded protein required for phi 29 DNA replication in vivo. Protein p5 has single-stranded DNA binding (SSB) capacity and stimulates in vitro DNA replication severalfold when phi 29 DNA polymerase is used to replicate either the natural phi 29 DNA template or primed M13 single-stranded DNA (ssDNA). Furthermore, other SSB proteins, including Escherichia coli SSB, T4 gp32, adenovirus DNA-binding protein, and human replication factor A, can functionally substitute for protein p5. The stimulatory effect of phi 29 protein p5 is not due to an increase of the DNA replication rate. When both phi 29 DNA template and M13 competitor ssDNA are added simultaneously to the replication reaction, phi 29 DNA replication is strongly inhibited. This inhibition is fully overcome by adding protein p5, suggesting that protein p5-coated M13 ssDNA is no longer able to compete for replication factors, probably phi 29 DNA polymerase, which has a strong affinity for ssDNA. Electron microscopy demonstrates that protein p5 binds to M13 ssDNA forming saturated complexes with a smoothly contoured appearance and producing a 2-fold reduction of the DNA length. Protein p5 also binds to ssDNA in the phi 29 replicative intermediates produced in vitro, which are similar in structure to those observed in vivo. Our results strongly suggest that phi 29 protein p5 is the phi 29 SSB protein active during phi 29 DNA replication.
Performance of a commercially available in-clinic ELISA for the detection of antibodies against Anaplasma phagocytophilum, Ehrlichia canis, and Borrelia burgdorferi and Dirofilaria immitis antigen in dogs (2010)

The commercially available in-clinic ELISA could be used by veterinarians to screen dogs for heartworm infection and for exposure to tick-borne pathogens.
Decreased axon caliber and neurofilaments in hereditary motor and sensory neuropathy, Type I (1984)

The axons of large- and intermediate-diameter myelinated fibers of sural nerves of patients with hereditary motor and sensory neuropathy, type I (HMSN-I), were previously found to be attenuated relative to their myelin spiral length. We inferred that axonal atrophy might account for secondary segmental demyelination and remyelination. To assess whether the observed axonal atrophy could be explained by a decrease in neurofilaments, we have evaluated the number of neurofilaments, microtubules, and other axon organelles in sural nerves of patients with HMSN-I. Whereas the density per square micrometer of neurofilaments or microtubules in diseased nerves was not significantly different from that in control specimens, the number of neurofilaments per axon as related to myelin spiral length was significantly less for intermediate and large myelinated fibers in HMSN-I nerves. The regression lines for the number of microtubules per axon on myelin spiral lengths were also less steep in HMSN-I, but the difference did not reach statistical significance. These results indicate that the number of neurofilaments is proportional to axon diameter but significantly below that expected considering myelin spiral length. Decreased neurofilament synthesis, assembly, or transport may underlie the axonal atrophy in HMSN-I.
PAX8 is expressed in pancreatic well‐differentiated neuroendocrine tumors and in extrapancreatic poorly differentiated neuroendocrine carcinomas in fine‐needle aspiration biopsy specimens (2011)

Pancreatic well-differentiated neuroendocrine tumors frequently express PAX8, which can help distinguish pancreatic primary tumors from tumors of other anatomic sites. In contrast, PAX8 expression in poorly differentiated neuroendocrine carcinomas is not specific for pancreatic origin and can be seen in extrapancreatic poorly differentiated neuroendocrine carcinomas.
Laboratory and field trials at Ifakara (Kilombero District, Tanzania) on the plant molluscicide Swartzia madagascariensis. (1986)

The molluscicidal activity of crushed seed pods of Swartzia madagascariensis was assessed by laboratory and field trials. Mature dry seed pods were ground and extracted in tap water for 24 h. Water extracts exerted a significant molluscicidal activity against Bulinus globosus up to dilutions of 100 mg of ground pods per litre. The chromatographically isolated saponin (1) responsible for the molluscicidal activity showed a toxicity of LC 100 at 3 mg/l after exposure of B. globosus and Biomphalaria glabrata for 24 h. Saponin (1) could be identified by FAB-MS and 13C-NMR-spectroscopy as oleanolic acid-3-O-beta-D-glucuronopyranosyl (1----3)-alpha-L-rhamnopyranoside. Two field trials with S. madagascariensis pod extracts in ponds (60 and 160 m3) harbouring dense populations of B. globosus compared well with the laboratory findings and showed the efficiency of the molluscicide in a natural habitat. A single application of the plant molluscicide significantly reduced the populations of B. globusus. The toxicity of S. madagascariensis pod extracts to non-target organisms remains an obstacle for its use in certain situations where schistosomiasis control is envisaged and where S. madagascariensis is found. However, S. madagascariensis is a valid candidate molluscicide which may be applied in selected epidemiological settings as part of integrated schistosomiasis control measures.
Self‐Assembled Octadecyltrimethoxysilane Monolayers Enabling Selective‐Area Atomic Layer Deposition of Iridium (2006)

A preparation method for octadecyltrimethoxysilane (ODS) self‐assembled monolayers (SAMs) that enables the selective‐area ALD of iridium is studied using an ALD process for iridium at 225 °C. ODS SAMs were prepared from the gas phase by two preparation methods: either with exposure to ODS only, or with alternate exposures to ODS and water. SAMs were patterned with a lift‐off process using aluminium as a mask layer.
Novel Streptavidin-Functionalized Silicon Nanowire Arrays for CD4<sup>+</sup> T Lymphocyte Separation (2010)

Silicon nanowires (SiNWs) offer promising inorganic nanostructures for biomedical application. Here, we report the development of a novel SiNW array designed for isolating primary CD4(+) T lymphocytes from the heterogeneous mixture of cell populations. Our system employed the specific high-affinity binding features of streptavidin (STR)-functionalized SiNW with biotin-labeled CD4(+) T lymphocytes. Fabricated SiNW arrays easily separated the CD4(+) T lymphocytes from the mouse whole splenocytes with over approximately 88% purity and demonstrated tight attachment to CD4(+) T lymphocytes by scanning electron microscopy. Thus, our STR-SiNW arrays provide a potential tool for specific cell separation and further present a possibility to be applied to the other area of biomedical applications.
Intra-slot Interference Cancellation for collision resolution in Irregular Repetition Slotted ALOHA (2015)

ALOHA-type protocols became a popular solution for distributed and uncoordinated multiple random access in wireless networks. However, such distributed operation of the Medium Access Control (MAC) layer leads to sub-optimal utilization of the shared channel. One of the reasons is the occurrence of collisions when more than one packet is transmitted at the same time. These packets cannot be decoded and retransmissions are necessary. However, it has been recently shown that it is possible to apply signal processing techniques with these collided packets so that useful information can be decoded. This was recently proposed in the Irregular Repetition Slotted ALOHA (IRSA), achieving a throughput T ≃ 0.97 for very large MAC frame lengths as long as the number of active users is smaller than the number of slots per frame. In this paper, we extend the operation of IRSA with i) an iterative physical layer decoding processing that exploits the capture effect and ii) a Successive Interference Cancellation (SIC) processing at the slot-level, named intra-slot SIC, to decode more than one colliding packet per slot. We evaluate the performance of the proposed scheme, referred to as Extended IRSA (E-IRSA), in terms of throughput and channel capacity. Computer-based simulation results show that E-IRSA protocol allows to reach the maximum theoretical achievable throughput even in scenarios where the number of active users is higher than the number of slots per frame. Results also show that E-IRSA protocol significantly improves the performance even for small MAC frame lengths used in practical scenarios.
Brecht and Godard in Ten Scenes from The Decline and Fall of Aristotle (1970)

Research Article| November 01 1970 Brecht and Godard in Ten Scenes from The Decline and Fall of Aristotle Joel Schechter Joel Schechter Search for other works by this author on: This Site Google Theater (1970) 3 (1_Film): 25–30. https://doi.org/10.1215/00440167-3-1_Film-25 Cite Icon Cite Share Icon Share Twitter Permissions Search Site Citation Joel Schechter; Brecht and Godard in Ten Scenes from The Decline and Fall of Aristotle. Theater 1 November 1970; 3 (1_Film): 25–30. doi: https://doi.org/10.1215/00440167-3-1_Film-25 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsTheater Search Advanced Search The text of this article is only available as a PDF. Copyright © by yale/theatre 19701970 Article PDF first page preview Close Modal You do not currently have access to this content.
Network aspects relevant to the integration between the GSM network and a satellite system (2002)

The integration between cellular and satellite systems permits to provide wider and more efficient area coverage. In this paper the viability of a full integration between the GSM cellular network and a spot-beam satellite system is dealt with. The integration analysis focuses on the network aspects. Full integration means to reuse, as far as possible, the same equipment and protocols, i.e. the same hardware and software, for the satellite and the GSM network. In the integrated system the user need not be aware whether the actual connection goes through the satellite or the GSM network. The paper identifies the most promising satellite system configuration and the satellite system counterpart of the GSM functional areas (cell, location area, MSC area). Moreover, the problems and the relevant solutions related to the extension of the GSM procedures (e.g. call set-up, cell selection/reselection, handover, initial acquisition, tracking) to the satellite system are dealt with.
The Degradation of Trichloroethylene in Mixed Methanogenic Cultures (1989)

Abstract Symbiosis between nonmethanogenic fermenters and methanogens, which occurs through a phenomenon called the interspecies hydrogen transfer, can play an important role in the growth of these microorganisms. In the degradation of natural materials, methane production is frequently supported by this interspecies hydrogen transfer from fermenters that degrade the primary substrate, to methanogens that use the hydrogen to reduce carbonate to methane. The objective of this work was to evaluate the role of the fermenters in the degradation of trichloroethylene during methanogenesis. The results show that the fermentation process enhances the anaerobic degradation of trichloroethylene. In addition, it is shown that chloroethane appears as one of the products of the degradation of trichloroethylene by this mixed culture. The production of chloroethane indicates that hydrogenation of the double bond of a chlorinated ethene occurs during the degradation of trichloroethylene by cultures containing nonmethanogenic fermenters and methanogens. The metabolism involved in this degradation process may therefore provide a possible mechanism to completely degrade trichloroethylene under anaerobic conditions, because it is known that chloroethane is degraded rapidly to inorganic carbon.