gebhart/patrepeval huggingface dataset:
Security in a Distributed Key Management Approach (2017)

Cloud computing offers many advantages as flexibility or resource efficiency and can significantly reduce costs. However, when sensitive data is outsourced to a cloud provider, classified records can leak. To protect data owners and application providers from a privacy breach data must be encrypted before it is uploaded. In this work, we present a distributed key management scheme that handles user-specific keys in a single-tenant scenario. The underlying database is encrypted and the secret key is split into parts and only reconstructed temporarily in memory. Our scheme distributes shares of the key to the different entities. We address bootstrapping, key recovery, the adversary model and the resulting security guarantees.
Performance of hybrid-ARQ in block-fading channels: A fixed outage probability analysis (2010)

This paper studies the performance of hybrid-ARQ (automatic repeat request) in Rayleigh block-fading channels. The long-term average transmitted rate is analyzed in a fast-fading scenario where the transmitter only has knowledge of channel statistics, and, consistent with contemporary wireless systems, rate adaptation is performed such that a target outage probability (after a maximum number of H-ARQ rounds) is maintained. H-ARQ allows for early termination once decoding is possible, and thus is a coarse, and implicit, mechanism for rate adaptation to the instantaneous channel quality. Although the rate with H-ARQ is not as large as the ergodic capacity, which is achievable with rate adaptation to the instantaneous channel conditions, even a few rounds of H-ARQ make the gap to ergodic capacity reasonably small for operating points of interest. Furthermore, the rate with H-ARQ provides a significant advantage compared to systems that do not use H-ARQ and only adapt rate based on the channel statistics.
DNA methylation profiles delineate etiologic heterogeneity and clinically important subgroups of bladder cancer (2010)

DNA methylation profiles can be used to define molecular cancer subtypes that may better inform disease etiology and clinical decision-making. This investigation aimed to create DNA methylation profiles of bladder cancer based on CpG methylation from almost 800 cancer-related genes and to then examine the relationship of those profiles with exposures related to risk and clinical characteristics. DNA, derived from formalin-fixed paraffin-embedded tumor samples obtained from incident cases involved in a population-based case-control study of bladder cancer in New Hampshire, was used for methylation profiling on the Illumina GoldenGate Methylation Bead Array. Unsupervised clustering of those loci with the greatest change in methylation between tumor and non-diseased tissue was performed to defined molecular subgroups of disease, and univariate tests of association followed by multinomial logistic regression was used to examine the association between these classes, bladder cancer risk factors and clinical phenotypes. Membership in the two most methylated classes was significantly associated with invasive disease (P < 0.001 for both class 3 and 4). Male gender (P = 0.04) and age >70 years (P = 0.05) was associated with membership in one of the most methylated classes. Finally, average water arsenic levels in the highest percentile predicted membership in an intermediately methylated class of tumors (P = 0.02 for both classes). Exposures and demographic associated with increased risk of bladder cancer specifically associate with particular subgroups of tumors defined by DNA methylation profiling and these subgroups may define more aggressive disease.
Hydrogen bonding mediated enantioselective organocatalysis in brine: significant rate acceleration and enhanced stereoselectivity in enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins (2011)

Brine provides remarkable rate acceleration and a higher level of stereoselectivity over organic solvents, due to the hydrophobic hydration effect, in the enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins using chiral H-donors as organocatalysts.
Conflict resolution strategies and their performance models for large-scale multiagent systems (2003)

Distributed, collaborative agents are promising to play an important role in large-scale multiagent applications, such as distributed sensors and distributed spacecraft. Since no single agent can have complete global knowledge in such large scale applications, conflicts are inevitable even among collaborative agents over shared resources, plans, or tasks. Fast conflict resolution techniques are required in many multiagent systems under soft or hard time constraints. In resolving conflicts, we focus on the approaches based on DCSP (distributed constraint satisfaction problems), a major paradigm in multiagent conflict resolution. We aim to speed up conflict resolution convergence via developing efficient DCSP strategies. 
We focus on multiagent systems characterized by agents that are collaborative, homogeneous, arranged in regular networks, and relying on local communication (found in many multiagent applications). This thesis provides the followings major contributions. 
First, we develop novel DCSP strategies that significantly speed up conflict resolution convergence. The novel strategies are based on the extra communication of local information between neighboring agents. We formalize a set of DCSP strategies which exploit the extra communication: in selecting a new choice of actions, plans, or resources to resolve conflicts, each agent takes into account how much flexibility is given to neighboring agents. Second, we provide a new run-time model for performance measurement of DCSP strategies since a popular existing DCSP performance metric does not consider the extra communication overhead. The run-time model enables us to evaluate the strategy performance in various computing and networking environments. Third, the analysis of message processing and communication overhead of the novel strategies shows that such overhead caused by the novel strategy is not overwhelming. Thus, despite extra communication, the novel strategies indeed show big speedups in a significant range of problems (particularly for harder problems). Fourth, we provide categorization of problem settings with big speedups by the novel strategies Finally, to select the right strategy in a given domain, we develop performance modeling techniques based on distributed POMDP (Partially Observable Markov Decision Process) based model where scalability issue is addressed with a new decomposition technique.
Synthesis of Polysubstituted 5-Azaindoles via Palladium-Catalyzed Heteroannulation of Diarylalkynes (2011)

A general and efficient procedure for the synthesis of functionalized 5-azaindoles through the catalyzed heteroannulation of 4-acetamido-3-iodopyridines and diarylalkynes is described. The reaction allows the preparation of a variety of substituted 2,3-diaryl-5-azaindoles in good to excellent yields.
Irrigation's influence on precipitation: Texas High Plains, U.S.A. (2002)

Using bias‐corrected Nexrad precipitation estimates and spatial statistics of rainfall intensity, we examine the influence of irrigation on summer precipitation in the Texas High Plains. In this region, human alteration of the surface water and energy balance has been extreme. Irrigation enhances precipitation downwind, yielding storms of greater duration, length, and accumulation. Irrigation water is not a significant source of moisture feeding precipitation; rather, the cool, wet surface increases low‐level instability, triggering storms. We estimate that an additional 6% to 18% of summer precipitation attributable to irrigation falls ∼90 km downwind of the irrigated region.
An adaptive randomized discontinuation trial of XL184 (BMS-907351) in patients (pts) with advanced solid tumors. (2010)

TPS188 Background: XL184 is an oral, potent inhibitor of MET, VEGFR2, and RET with promising activity in phase I and II trials. We designed a phase II randomized discontinuation trial to evaluate the activity of XL184 in various solid tumors where MET signaling plays an important role. Pts with breast, gastric/gastroesophageal junction, small cell lung, non-small cell lung, ovarian, pancreatic, hepatocellular, melanoma, and prostate cancer are being evaluated in this study. The aim is to assess XL184 clinical activity in a blinded, randomized setting while minimizing exposure to placebo (P) and enriching the study population with disease stabilization using an open label treatment phase prior to randomization. Methods: Approximately 600 pts with a diagnosis of advanced, metastatic, or recurrent solid tumors are eligible for one of nine tumor-specific cohorts. The study consists of two stages: open label Lead-In Stage (Stage1), and double-blinded Randomized Stage (Stage2). In Stage1, all pts receive XL184 daily for 12 weeks. At the end of Stage1, complete/partial responders by modified RECIST continue to receive XL184; progressive disease (PD) pts discontinue XL184; stable disease (SD) pts are randomized 1:1 to receive XL184 or P in Stage2 until PD. Pts randomized to P may cross over to XL184 upon PD. Efficacy endpoints include objective response rate (ORR) in Stage1, and progression free survival in Stage2 evaluated when 52 events (PD or death) are observed per cohort. Fifty two events achieve 80% power to detect a hazard ratio of 0.5 with a 2-sided alpha of 0.1. Accrual will be stopped early for cohorts that demonstrate a low randomization rate due to overwhelming ORR, PD, low SD rate (SDR), or low accrual. The stopping guidelines employ lower 95% confidence limits for ORR to evaluate anti-tumor activity, and conditional probabilities to project futility. Two hundred pts are required to identify cohorts for early stopping, and 400 pts are required for full accrual in Stage2 for two cohorts with a high SDR and favorable safety profile. Clinical efficacy will be correlated with tumor pathway dysregulation as assessed in archival tumor tissue to further characterize the cohort(s) which benefit from XL184 treatment. Author Disclosure Employment or Leadership Position Consultant or Advisory Role Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Exelixis Bristol-Myers Squibb, Exelixis Exelixis Bristol-Myers Squibb, Exelixis
Test of a Threshold-Based Earthquake Early-Warning Method Using Japanese Data (2012)

Most of existing earthquake early‐warning systems are regional or on‐site systems. A new concept is the integration of these approaches for the definition of alert levels and the estimation of the earthquake potential damage zone (PDZ). The key element of the method is the real‐time, simultaneous measurement of initial peak displacement (P_d) and period parameter (τ_c) in a 3‐s window after the first P‐wave arrival time at accelerometer stations located at increasing distances from the epicenter. As for the on‐site approach, the recorded values of P_d and τ_c are compared to threshold values, which are set for a minimum magnitude M 6 and instrumental intensity I_MM VII, according to empirical regression analysis of strong‐motion data from different seismic regions. At each recording site the alert level is assigned based on a decisional table with four entries defined by threshold values of the parameters P_d and τ_c. A regional network of stations provides the event location and transmits the information about the alert levels recorded at near‐source stations to more distant sites, before the arrival of the most destructive phase.\n\nWe present the results of performance tests of this method using ten M>6 Japanese earthquakes that occurred in the period 2000–2009 and propose a very robust methodology for mapping the PDZ in the first seconds after a moderate‐to‐large earthquake. The studied cases displayed a very good matching between the rapidly predicted earthquake PDZ inferred from initial P‐peak displacement amplitudes and the instrumental intensity map, the latter being mapped after the event, using peak ground velocity and/or acceleration, or from field macroseismic surveys.
Potential defense applications of expert systems (1988)

The authors provide an overview of expert systems and how they may effect the development of future defense applications. Military uses of computers are outlined, and expert-systems fundamentals are described. Artificial research and development efforts by the military are examined, and potential military applications are discussed. Expert systems efforts at NASA, by the US Air Force, and for the Strategic Defence Initiative are considered.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
On Deadlock Detection in Distributed Systems (1980)

A hierarchically organized and a distributed protocol for deadlock detection in distributed databases are presented in [1]. In this paper we show that the distributed protocol is incorrect, and present possible remedies. However, the distributed protocol remains impractical because "condensations" of "transaction-wait-for" graphs make graph updates difficult to perform. Delayed graph updates cause the occurrence of false deadlocks in this as well as in some other deadlock detection protocols for distributed systems. The performance degradation that results from false deadlocks depends on the characteristics of each protocol.
Anaerobic digestion of maize in coupled leach-bed and anaerobic filter reactors (2008)

The methane potential of a leach bed reactor (LBR) coupled to an anaerobic filter (AF) was assessed using energy maize (Zea mays) as substrate. Four LBRs were used operated as pairs, with and without leachate recirculation, over two feed cycles with retention times of 14 and 28 days. Performance was estimated from the total solids destruction in the LBR, and the volatile fatty acid (VFA) and soluble chemical oxygen demand (SCOD) in the leachate. Overall conversion of fresh substrate added to the combined system was good although the organic loading rate (OLR) was limited. The coupled LBR demonstrated improved hydrolysis performance promoted by good buffering, and the AF showed rapid conversion of leachate SCOD into methane with possible further hydrolysis and acidification. Theoretical estimation of the methane potential showed that between 20-40% of the methane was formed in the LBR and was not captured in this trial.
<title>Pyramid-based multisensor image data fusion</title> (1997)

In this work, a multi-resolution procedure based on a generalized Laplacian pyramid (GLP), with p:q (i.e. rational) scale factor, is proposed to merge image data of any resolution and represent them at any scale. The GLP- based data fusion is shown to be slightly superior to those of a similar scheme based on the discrete wavelet transform (WT), according to a set of parameters established in the literature. Not only fused images look sharper than their original versions, but also textured regions are enhanced without losing their spectral signatures. The pyramid- generating filters can be easily designed for data of any resolutions, differently from the WT, whose filter-bank design is non-trivial when the ratio between the scales of the images to be merged is not a power of two. Eventually, remotely sensed images from LandSat TM and from Panchromatic SPOT are fused together. The resulting bands capture multi- spectral features with enhanced contrast and texture, and an increased spatial resolution, thereby expediting automatic analyses for contextual interpretation of the environment.
Influence of ionic liquid and ionic salt on protein against the reactive species generated using dielectric barrier discharge plasma (2015)

The presence of salts in biological solution can affect the activity of the reactive species (RS) generated by plasma, and so they can also have an influence on the plasma-induced sterilization. In this work, we assess the influence that diethylammonium dihydrogen phosphate (DEAP), an ionic liquid (IL), and sodium chloride (NaCl), an ionic salt (IS), have on the structural changes in hemoglobin (Hb) in the presence of RS generated using dielectric barrier discharge (DBD) plasma in the presence of various gases [O2, N2, Ar, He, NO (10%) + N2 and Air]. We carry out fluorescence spectroscopy to verify the generation of (•)OH with or without the presence of DEAP IL and IS, and we use electron spin resonance (ESR) to check the generation of H(•) and (•)OH. In addition, we verified the structural changes in the Hb structure after treatment with DBD in presence and absence of IL and IS. We then assessed the structural stability of the Hb in the presence of IL and IS by using molecular dynamic (MD) simulations. Our results indicate that the IL has a strong effect on the conservation of the Hb structure relative to that of IS against RS generated by plasma.
A semantic model of reference counting and its abstraction (detailed summary) (1986)

Article A semantic model of reference counting and its abstraction (detailed summary) Share on Author: Paul Hudak Yale University, Department of Computer Science, Box 2158 Yale Station, New Haven, CT Yale University, Department of Computer Science, Box 2158 Yale Station, New Haven, CTView Profile Authors Info & Claims LFP '86: Proceedings of the 1986 ACM conference on LISP and functional programmingAugust 1986 Pages 351–363https://doi.org/10.1145/319838.319876Online:08 August 1986Publication History 116citation455DownloadsMetricsTotal Citations116Total Downloads455Last 12 Months16Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Inquisition et mutations sociales des conversos à Séville : des réformes complexes de société entre 1480 et 1523 (2006)

IntroductionAinsi que le titre tente de le suggérer, nous accorderons au terme de « réformes » un sens général plus proche de l’origine latine du terme reformatio : celui d’une mutation, d’une restauration, d’une amélioration, dans le sens d’un retour à des mœurs jugées meilleures1.Il est de bon ton cette année – au regard de la question d’agrégation qui lie l’Inquisition
Computation of Switching Noise in Printed Circuit Boards (1996)

http://deepblue.lib.umich.edu/bitstream/2027.42/21074/2/rl0934.0001.001.pdf
Hierarchical structure for supporting movable base stations in wireless networks (2003)

Wireless networks with movable base stations combine the advantages of mobile ad hoc networks and wireless LAN to achieve both flexibility and scalability. We present the hierarchical mobile wireless network (HMWN) to support movable base stations. HMWN may be applied to ad hoc networks as well to build a virtual hierarchy. In such a system, mobile hosts are organized into hierarchical groups. Four basic operations for setting up and maintaining the network structure are grouping, registration, leaving, and migration. An efficient group membership management protocol is developed to support mobile hosts roaming among different groups. The segmented membership-based group routing (SMGR) protocol is proposed to take advantage of the hierarchical structure and membership information. In this protocol, only local message exchanging is required for maintaining network topology and routing information. Simulation-based experiment demonstrates the scalability of the design in terms of protocol overheads.
Real-Time Receding-Horizon Control Algorithm for Nonlinear Systems (1997)

A real-time optimization technique is proposed for optimal state feedback control of general nonlinear systems. A state feedback control law is determined so that a receding-horizon performance index is minimized. Computation of the control input is equivalent to solving a family of optimal control problems with a varying initial state in the real time, for which the stabilized continuation method is applicable. Application of the stabilized continuation method results in a real-time solution technique that does not involve any approximation nor iterative algorithm in principle. The proposed solution technique successfully implemented in a control experiment of a 2-wheeled mobile robot that is nonlinear and nonholonomic. Equilibrium points of the closed-loop system are also analyzed.
Self-binding antibodies (autobodies) form specific complexes in solution. (1990)

In this report we have shown that members of the murine self-binding antibody family, S107, form soluble complexes and precipitate under conditions in which non-self-binding antibodies remain in solution. Two approaches were used to demonstrate the self-association of autobodies: size-exclusion column chromatography and polyethylene glycol (PEG)-mediated precipitation assay. The anti-phosphorylcholine antibody T15 and two somatic variants, U4, which binds DNA, and U10, which has no identified specificity, produced larger precipitates in 10% PEG than other non-self-binding antibodies. The selectivity of PEG-mediated precipitation of self-binding antibodies is demonstrated by reduction of precipitation with specific haptens known to inhibit self-binding in solid-phase assays. Phosphorylcholine and nucleotides reduced precipitation of T15 and U4, respectively, but not U10. To rule out Fc-Fc mediated self-association in solution, we have also demonstrated self-complexing of F(ab')2 fragments of T15 using PEG. The self-binding locus was further dissected using peptides derived from V regions. A 24-residue peptide derived from the second hypervariable region of the VH of S107 specifically enhanced precipitation of T15, U4, and U10, but not other antibodies. These results provide evidence of a dormant potential of self-binding antibodies to precipitate under conditions that reduce the solubility of proteins. The implication of this potential is discussed with respect to pathological complex formation.
Stopcock For Gas Chromatography (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStopcock For Gas ChromatographyD N. Glew and D M. YoungCite this: Anal. Chem. 1958, 30, 11, 1890Publication Date (Print):November 1, 1958Publication History Published online14 June 2002Published inissue 1 November 1958https://pubs.acs.org/doi/10.1021/ac60143a640https://doi.org/10.1021/ac60143a640research-articleACS PublicationsRequest reuse permissionsArticle Views13Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts