gebhart/patrepeval huggingface dataset:
The Nutrition of Animal Tissues Cultivated <italic>In Vitro</italic>. I. A Survey of Natural Materials as Supplements to Synthetic Medium 199 (1955)

Journal Article The Nutrition of Animal Tissues Cultivated In Vitro. I. A Survey of Natural Materials as Supplements to Synthetic Medium 199 Get access Joseph F. Morgan, Joseph F. Morgan Laboratory of Hygiene, Department of National Health and Welfare, Ottawa, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Elizabeth Campbell, M. Elizabeth Campbell Laboratory of Hygiene, Department of National Health and Welfare, Ottawa, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Helen J. Morton Helen J. Morton Laboratory of Hygiene, Department of National Health and Welfare, Ottawa, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 16, Issue 2, October 1955, Pages 557–567, https://doi.org/10.1093/jnci/16.2.557 Published: 01 October 1955 Article history Received: 08 April 1955 Published: 01 October 1955
Electronic spectoscopy of isoelectronic molecules. II. Linear triatomic groupings containing sixteen valence electrons (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectronic spectoscopy of isoelectronic molecules. II. Linear triatomic groupings containing sixteen valence electronsSean P. McGlynn, John W. Rabalais, Jimmie R. McDonald, and V. M. ScherrCite this: Chem. Rev. 1971, 71, 1, 73–108Publication Date (Print):February 1, 1971Publication History Published online1 May 2002Published inissue 1 February 1971https://doi.org/10.1021/cr60269a004RIGHTS & PERMISSIONSArticle Views828Altmetric-Citations462LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (3 MB) Get e-Alerts Get e-Alerts
The Measurement of Lewis Basicity and Affinity in the Laboratory (2009)

This chapter contains sections titled: Calorimetric Determination of the BF3 Affinity of Pyridine by Gas/Liquid Reaction Calorimetric Determination of the BF3 Affinity of Pyridine by Liquid/Liquid Reaction Determination by FTIR Spectrometry of the Complexation Constants of 4-Fluorophenol with Isopropyl Methyl Ketone and Progesterone Determination by FTIR Spectrometry of the Complexation Enthalpy and Entropy of 4-Fluorophenol with Cyclopropylamine FTIR Determination of the OH Shift of Methanol Hydrogen Bonded to Pyridine, Mesitylene and N-Methylmorpholine Solvatochromic Shifts of 4-Nitrophenol upon Hydrogen Bonding to Nitriles Determination of the Complexation Constant of Diiodine with Iodocyclohexane by Visible Spectrometry Determination of the Complexation Enthalpy and Entropy of Diiodine with Dimethyl Sulfoxide by Visible Spectrometry FTIR Determination of the Shift of the IC Stretching of Iodine Cyanide upon Halogen Bonding to Phosphine Chalcogenides Blue Shift of the Visible Diiodine Transition Upon Halogen Bonding to Pyridines Mass Spectrometric Determination of the Gas-Phase Lithium Cation Basicity of Dimethyl Sulfoxide and Methyl Phenyl Sulfoxide by the Kinetic Method References
A method of reducing diffusion losses in a drift spectrometer (1999)

A method is considered which reduces diffusion losses during analysis of the ions of heavy molecules passed together with a carrier gas through a separation system at atmospheric pressure. Separation takes place under the action of a transverse variable electric field in a way similar to the case of quadrupole mass spectrometers. Instead of the usual uniform-field planar capacitor, it is proposed to employ a cylindrical capacitor with a nonuniform field. It is shown experimentally that a severalfold increase in the output signal is achieved.
A Time-Interleaved Multimode RF-DAC for Direct Digital-to-RF Synthesis (2016)

A multimode delta-sigma (ΔΣ) RF digital-to-analog converter (RF-DAC) is proposed for direct digital-to-RF synthesis. The proposed circuit uses a single clock frequency (f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> ) and provides a ΔΣ modulator (DSM) that operates in bandpass (BP) and highpass (HP) modes to synthesize signals around f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> /4, f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> /2, or 3f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> /4. The on-chip 14 bit second-order DSM implements an array of 1 bit pipelined subtract functions to generate 3 bit f8 rate RF-DAC input data. Analog interleaving via a second 3 bit DAC is used to reject the first DAC image, simultaneously doubling the usable bandwidth of the HP DSM and increasing the SNR. Calibration circuits are added to the DAC to compensate for amplitude and timing variations. The proposed RF-DAC is implemented in 130 nm SiGe BiCMOS with an area of 0.563 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . Measurements at f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> = 2 GHz yield an output power of -0.6 dBm with 76.2 dB signal-to-image-rejection ratio (SIRR), 76.2 dB SFDR over a 100 MHz bandwidth, -80 dBc IM3, -67.2 dB WCDMA ACLR, and -66.4 dBc LTE ACLR. Changing f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> to 3 GHz allows frequencies of 2.25 GHz to be generated with output power of -16.6 dBm, 65.2 dB SFDR, -62 dBc IM3, -59.3 dB WCDMA ACLR, and -59.2 dBc LTE ACLR.
SOME ASPECTS OF FLOWERING, GIBBOSITY AND TURION FORMATION IN LEMNACEAE (1973)

Literature on Lemnaceae is reviewed with regard to experimental control of flowering, gibbosity and turion formation by chelating agents, metal ions and growth regulators. Possible mechanisms by which chelating agents and metal ions influence flowering are discussed.
Abstract B249: Prolonged cytotoxic activity induced by anti-PSMA x anti-CD3 ADAPTIR™ molecule in the absence of significant cytokine release. (2013)

Abstract Background: Treatment of metastatic, castrate-resistant prostate cancer (CRPC) remains a highly unmet medical need. We have developed a humanized bispecific ADAPTIR™ (modular protein technology) molecule, ES414, which redirects T-cell cytotoxicity against cells expressing PSMA (Prostate Specific Membrane Antigen), a prostate cancer antigen. In previous preclinical studies, ES414 has been shown to induce cytotoxicity against prostate cancer cells in vitro when measured by target cell lysis and in vivo in multiple mouse xenograft models. ES414 was also previously shown to be well-tolerated in humanized mice and non-human primates. Here, we examine the effects of exposure to ES414 over several days on T-cell function in the presence of PSMA+ target cells.Materials and Methods: Long term cytotoxic activity induced by ES414 against PSMA(+) cell lines in the presence of purified human T cells was followed in vitro by use of high content microscopy. Cytotoxic activity was determined by incorporation of a label such as propidium iodide or 7-aminoactinomycin D. Binding to subsets of peripheral blood mononuclear cells (PBMC) and Fc(gamma) receptor-expressing cell lines was assessed by multi-color flow cytometry. T cells were assessed for activation and proliferation in a similar setting using multi-color flow cytometry. Cytokine release was measured at multiple timepoints using multiplex immunoassays. Results: ES414 selectively bound to T cells, and did not bind to other PBMC subsets nor to Fc (gamma) receptor expressing cell lines. T cells activated by ES414 in the presence of target cells rapidly induced target cell lysis within 4 hours and continued serial lysis for more than 48 hours. Target cell lysis occurred at low effector-to-target cell ratios. In the presence of target cells, ES414 also induced T-cell activation, as measured by upregulation of activation markers, and proliferation, but induced limited levels of cytokine secretion in comparison to control molecules. Conclusions: These preclinical in vitro studies show that ES414 selectively engages T cells, targets T cells towards tumor cells, and induces T-cell activation, with limited cytokine release. Limited cytokine release in the presence of redirected T-cell cytotoxicity is a desirable feature that warrants further investigation of ES414 as a potential therapeutic for CRPC. Citation Information: Mol Cancer Ther 2013;12(11 Suppl):B249. Citation Format: Gabriela Hernandez-Hoyos, Toddy Sewell, Padma Ravikumar, Megan Aguilar, John Kumer, David Bienvenue, Catherine J. McMahan, Jane Gross, John W. Blankenship. Prolonged cytotoxic activity induced by anti-PSMA x anti-CD3 ADAPTIR™ molecule in the absence of significant cytokine release. [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2013 Oct 19-23; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Ther 2013;12(11 Suppl):Abstract nr B249.
An Innovative Application to Reduce Petrophysical Uncertainty in Reservoir Monitoring: Case Studies from Giant Saudi Arabian Fields (2005)

Abstract Reservoir monitoring requires an accurate assessment of hydrocarbon saturation. As oil fields mature, reducing uncertainty in this parameter can yield major economic benefits in field development and reservoir management. Recent advancements in resistivity tool design and enhancements in pulsed neutron and NMR tools have expanded the scope of petrophysics in reservoir monitoring projects. Optimal utilization of these technologies requires an understanding of the uncertainties that are associated with these measurements in different types of environments. A new application has been developed that uses numerical analysis to compute the range of uncertainties inherent in petrophysical analysis. These uncertainties are then used as guidelines to optimize data acquisition. This methodology defines petrophysical uncertainties on a foot-by-foot basis; consequently decisions are based on prior knowledge of the uncertainty of two of the most important petrophysical parameters, water saturation and porosity. Several wells have been used in this paper to demonstrate the utility of this application and how this analysis is used to design cost-effective logging programs. Even though this technique can be used with any logging measurements, the focus of this paper will be on resistivity and pulsed neutron devices which are widely used in reservoir monitoring. The examples will show how quantifying uncertainties of key petrophysical parameters reduces reservoir management risk.
Towards automated deployment of IEC 61131-3 applications on multi-core systems (2016)

The IEC 61131-3 standard, a widely used standard in the automation industry, defines various programming languages for programmable logic controllers. Today, the open source tools that comply with this standard do not support deployment of the applications on multi-core platforms. In this paper, we introduce a novel multi-step approach that aims to support automatic deployment of the automation control applications, developed using the IEC 61131-3 standard, to multi-core platforms. In the first step, the generated sequential code is partitioned. In the second step, the partitioned code is allocated to tasks while the tasks are mapped to various cores, without violating the dependencies, synchronization and communication constraints in the application. In order to provide a proof of concept, we develop a prototype by extending an existing tool that complies with the standard. We also perform a case study and a preliminary evaluation of the prototype.
Human Machine Joint Decision Making in Distorted Surveillance Scenario (2019)

There is plenty of human-machine joint decision-making scenarios in the real world applications, such as driving assistant, suspect identification, medical diagnosis, etc. Existing algorithms propose that machine should give a rejection option when having a high risk or uncertainty score so that the input can be passed to human to make the decision. This is an interesting algorithmic model of human-machine collaboration, but implicitly assumes that humans are more trustworthy than machines. Such an assumption ignores the bias and inconsistency of human, especially in scenarios where machines have superior recognition ability than humans. In this work, we investigate the human-machine joint decision-making problem in distorted surveillance videos, where machines experimentally prove to be comparable to human beings in tolerance to distortion, sometimes even stronger. We propose a new human-machine joint decision-making framework by considering both the confidences of machine and human. To obtain the confidence of human, we build a real-life human decision-making database and propose a deep neural network to estimate human's confidence. Then, confidence alignment method and decision rule are proposed to further output the final decision. Experiments demonstrate that the proposed framework can make less human intervention and more accurate decisions in several human-machine joint decision-making scenarios.
Synthesis, characterization, and chromatographic evaluation of titanium tetrabutoxide-modified silica as a support for HPLC-RP separations in alkaline mobile phases (2001)

Gamma radiation was used to immobilize poly(methyloctylsiloxane) (PMOS) onto the surface of silica particles titanized by reaction with titanium tetrabutoxide. The irradiated particles were extracted with CH2Cl2 and subsequently packed into HPLC columns for testing. The PMOS–based stationary phases were tested chromatographically after each of a series of washings with pH 7 and pH 12 MeOH : NaOH(aq) 70 : 30 (v/v) mobile phases. Very slight decreases in column efficiency or retention time and no evidence of support dissolution were observed with either mobile phase
A Study on the Problem Analysis and Quality Improvement in Fabricating Free-Form Buildings Facade Panels through Mock-up Panels Production (2011)

비정형 건축물은 건축가의 디자인 의도를 반영한 다양한 형태의 외장 디자인을 포함한다. 이러한 비정형 형태의 외장부재는 NURBS (Non-Uniform Rational B-Spline) 라 불리는 이 방향 곡률로 구성된 불규칙한 자유곡선면을 포함하고 있어 실제 외장부재의 생산 및 시공을 위해서는 3차원 비정형 BIM 기술을 적용한 패널최적화 단계를 거쳐야 한다. 본 연구에서는 역공학(Reverse Engineering) 기법을 근간으로 사례연구를 통해 비정형 건축물 BIM 도구인 디지털 프로젝트를 활용하여 패널형태를 구축하고 패널 최적화 결과를 도출한다. 최적화 결과 도출된 비정형 패널부재의 곡률 형상에 따른 Mock-Up 패널제작을 통해 패널종류에 따른 제작 용이성을 테스트하고 레이저 스케닝 기술을 사용하여 설계한 패널과 생산된 패널과의 데이터를 비교함으로써 이방향 곡률 곡면부재의 제작정밀도를 분석한다. Mock-Up 부재 제작 시 전문가 인터뷰를 통하여 국내에서 수행되고 있는 현행 비정형 외장부재 생산방식의 문제점을 도출하고 개선방안을 제시한다. The most critical issue in free-form buildings is how to construct the free-formed exterior facade panels. Their geometric complexity delivers many cons and problems in fabricating and constructing their shapes. To construct a free-form building, first of all, its skin has to be chopped into small pieces, which is called panelization. After panelization, the panels go through an optimization process to construct them economically. The panel's geometries are modified or regenerated through this optimization process. In this study, the panel optimization process of free-form buildings are performed through a case study. The panel shapes of the case study are modeled with Digital Project. To test the constructability of the various panels, 8 mock-up panels are made and laser scanning technology is applied to measure the preciseness of the panels manufactured in comparison with their original design.
Orientation of the Entomogenous NematodeNeoaplectana carpocapsaeto Carbon Dioxide1 (1980)

The behavioral response of infective stage juveniles of Neoaplectana carpocapsae to carbon dioxide was studied on an agar substrate. Exposure elicited a strongly positive response. Juveniles exhibited characteristic rearing and lateral motions of the head in migrating up the CO 2 gradient and aggregating at the source. The directed movement observed was attributed to klinotactic orientation. Maximum attraction was recorded at a flow rate of 4.1 ml/h; the range of attraction extended to 5 cm. Juvenile aggregations of approximately 60 and 90% were recorded within 30 and 50 mm, respectively, from a 2 cm distance. The pronounced response of N. carpocapsae to CO 2 suggests that this compound aids host finding.
<i>Testatin</i> : A cystatin-related gene expressed during early testis development (1998)

To isolate genes involved in morphogenic aspects of testis development, and which may act in cell signaling pathways downstream of the testis-determining gene Sry, we have developed a modified mRNA differential display method named signal peptide differential display. It was used to target those genes that encode proteins having a signal peptide sequence. By using this method, we isolated a gene named testatin. This gene was found to be related to a group of genes that encodes cysteine protease inhibitors known as cystatins. Cystatins and their target proteases have been associated with tumor formation and metastasis, but also are involved in natural tissue remodeling events such as bone resorption and embryo implantation. We show that testatin expression is restricted to fetal gonads and adult testis. Furthermore, testatin is expressed during testis cord formation in pre-Sertoli cells, believed to be the site of Sry action, at a time immediately after the peak of Sry expression. This finding suggests that testatin might be activated by transcription factors that are known to orchestrate the early testis development pathway. This gene therefore represents one of the putative downstream targets likely to have an essential role in tissue reorganization during early testis development.
Effect of<i>Bifidobacterium longum</i>BB536 yogurt administration on the intestinal environment of healthy adults. (1999)

A yogurt supplemented with B. longum BB536 was administered at 250 ml per day for 2 weeks to six healthy volunteers. The effects on the fecal microflora, fecal putrefactive substances, fecal enzymatic activities and fecal properties were examined and compared with the effects of standard yogurt. A significant increase (p<0.05) in the proportion of Bifidobacterium in the fecal microflora was observed following ingestion of yogurt containing B. longum BB536. The numbers of Lactobacillus also increased significantly (p<0.05). Clostridium sp. and total aerobic bacteria in the feces tended to decrease. The level of some putrefactive substances, including ammonia (p<0.05), indole and p -cresol decreased, whereas the levels of short chain and volatile fatty acids increased significantly (p<0.01). Urease activity decreased concomitant with the decrease in ammonia levels. These findings suggested that administration of yogurt containing B. longum BB536 was effective to improve the intestinal environment. Similar effects were observed with standard yogurt but they were less evident than in the case of yogurt containing B. longum BB536. Keywords: bifidobacteria, Bifidobacterium longum , yogurt, fecal flora, intestinal environment.
Video Paragraph Captioning Using Hierarchical Recurrent Neural Networks (2015)

We present an approach that exploits hierarchical Recurrent Neural Networks (RNNs) to tackle the video captioning problem, i.e., generating one or multiple sentences to describe a realistic video. Our hierarchical framework contains a sentence generator and a paragraph generator. The sentence generator produces one simple short sentence that describes a specific short video interval. It exploits both temporal- and spatial-attention mechanisms to selectively focus on visual elements during generation. The paragraph generator captures the inter-sentence dependency by taking as input the sentential embedding produced by the sentence generator, combining it with the paragraph history, and outputting the new initial state for the sentence generator. We evaluate our approach on two large-scale benchmark datasets: YouTubeClips and TACoS-MultiLevel. The experiments demonstrate that our approach significantly outperforms the current state-of-the-art methods with BLEU@4 scores 0.499 and 0.305 respectively.
A Simple Synthesis of C-8 Modified 2-Keto-3-deoxy-d-manno-octulosonic Acid (KDO) Derivatives (2010)

This paper describes a simple and efficient method with which to prepare C-8 modified 2-keto-3-deoxy-D-manno-octulosonic acid (KDO) derivatives from C-5 modified arabinose derivatives.
Sudden Enlargements in Pipelines (1962)

Study of hydraulic characteristics of sudden enlargements formed by placing orifices and valves in pipe lines; efficiency of sudden enlargements as energy dissipators, their cavitation potential, and methods for preventing cavitation damage to downstream water passage walls; characteristics of enlargements placed in series to dissipate energy of high head flows, and application to turbine bypasses.
Bundling dynamics of single walled carbon nanotubes in aqueous suspensions (2008)

A simple optical method based on absorption of monochromatic light to investigate the dynamics of single walled carbon nanotube (SWCNT) suspensions is described. The well dispersed suspensions display a complex behavior, exhibiting peaks due to resonant scattering from SWCNT bundles with increasing diameters as a function of time. The results indicate that the bundling of SWCNTs initiates almost immediately after termination of sonication (after ∼0.1 h) and continues to increase up to a critical time (∼10 h), above which precipitation according to the Stokes relationship occurs. The absorbance behavior can be explained by the depletion of the effective medium as well as the Mie scattering from growth of bundles. A semiquantitative analysis of the experimental data based on the Mie theory of light scattering from cylindrical particles allows the extraction of diameters at the nucleation and growth of SWCNT bundles. The bundling dynamics have been correlated with the electrical properties such as the sheet resistance and transistor characteristics of the SWCNT thin films. Our work is a useful step toward reproducible solution processed electronics because it provides a simple method to monitor the quality of SWCNT suspensions in real time and correlate it to device characteristics.
On the Framework for Network Measurement as a Service -- The perfSONAR-based Integrated Network Management (2010)

An integration of multiple-location, diverse-type, and long-term measurements has been considered a key means for continuous acquisition of the global status and for timely and cost-efficient identification of the causes of communication performance degradation. In addition, the measured data and analyzed results should be shared and reused for efficiency. Therefore, a global network measurement platform as a service is indispensible, which can provide integrated network monitoring and analysis functionality on-demand and can adapt to the purposes of the individual users (applications) and operators. In this report, we briefly introduce the design and implementation of an integrated network measurement system, together with a preliminary experiment on the Internet.