gebhart/patrepeval huggingface dataset:
Effect of a soccer ball’s surface texture on its aerodynamics and trajectory (2018)

The effect of a soccer ball’s surface texture on its aerodynamics and flight trajectory is not definitively known. For this study, five soccer balls were used, each having 32 panels with different surface textures. Their aerodynamics were examined via wind-tunnel experiments and then several non-spin trajectories were calculated for each ball. The results showed that the aerodynamic forces acting on a soccer ball change significantly depending on the surface texture of the ball, which in turn influences flight trajectories. The study contributes to an understanding of how a soccer ball’s surface influences the aerodynamics, which may impact the future design and development of soccer balls.
Enhanced phase synchrony in the electroencephalograph<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>γ</mml:mi></mml:math>band for musicians while listening to music (2001)

Multichannel electroencephalograph signals from two broad groups, 10 musicians and 10 nonmusicians, recorded in different states (in resting states or no task condition, with eyes opened and eyes closed, and with two musical tasks, listening to two different pieces of music) were studied. Degrees of phase synchrony in various frequency bands were assessed. No differences in the degree of synchronization in any frequency band were found between the two groups in resting conditions. Yet, while listening to music, significant increases of synchronization were found only in the gamma-frequency range (>30 Hz) over large cortical areas for the group of musicians. This high degree of synchronization elicited by music in the group of musicians might be due to their ability to host long-term memory representations of music and mediate access to these stored representations.
Comparison of deconvolution techniques using a distribution mixture parameter estimation: Application in single photon emission computed tomography imagery (2002)

The <i>Journal of Electronic Imaging</i> (JEI), copublished bimonthly with the Society for Imaging Science and Technology, publishes peer-reviewed papers that cover research and applications in all areas of electronic imaging science and technology.
Controlling Anterior Shear During Isokinetic Knee Extension Exercise (1982)

The purpose of this paper is to present a means of controlling anterior shear force at the knee during isokinetic exercise. A dual-pad attachment to existing exercise equipment allows selection of the degree of anterior shear placed on the knee during exercise, ranging from a value which apparently places minimal stress on ligamentous restraints, through intermediate shear levels, to a value nearly that of standard exercise equipment. The special problems associated with anterior cruciate ligament (ACL) involvement are reviewed in terms of ACL function, failure, and healing. Calculated loading configurations illustrate the effect on shear afforded by the device. A pilot roentgenographic study indicates restoration of normal tibiofemoral alignment and joint surface velocity vectors during isometric extension with the device. This preliminary finding correlates with clinical observation. Clinical application includes isokinetic exercise of the chronically lax knee and rehabilitation of the knee after ACL repair or reconstruction. J Orthop Sports Phys Ther 1982;4(1):23-31.
<sup>1</sup> H Magnetic resonance spectroscopy of extracts of human epileptic neocortex and hippocampus (1993)

We used high-resolution 1H magnetic resonance spectroscopy to determine the concentrations of several metabolites (lactate, alanine, N-acetylaspartate [NAA], gamma-aminobutyrate, glutamate, aspartate, creatine, cholines, taurine, inositol, and succinate) in tissue from patients undergoing surgical treatment of intractable epilepsy, and correlated the metabolite profiles with the results of histopathologic analysis of the excised tissue. We found no differences in metabolite levels for tissue from actively spiking or nonspiking neocortical sites in temporal lobe epilepsy patients. In neocortical tissue from patients with chronic localized encephalitis (Rasmussen's encephalitis), the metabolite concentrations varied with the severity and extent of the encephalitis. In tissue showing mild encephalitis and mild histologic abnormalities, the metabolite levels differed little from those found for nonencephalitic neocortical tissue. Tissue showing marked abnormalities and extensive encephalitis had decreased NAA, glutamate, cholines, and inositol. In hippocampal tissue from temporal lobe epilepsy patients, the levels of NAA, glutamate, and aspartate were lower and the levels of alanine, taurine, and inositol were higher than in neocortical tissue from the same patients. The decrease in the levels of NAA and glutamate was greater in gliotic hippocampal tissue. The results suggest that in vivo 1H magnetic resonance spectroscopy may aid in diagnosing the extent of chronic localized encephalitis and the severity of hippocampal gliosis.
A Hybrid Solid with Giant Pores Prepared by a Combination of Targeted Chemistry, Simulation, and Powder Diffraction (2004)

A perfect combination: The association of a chromium(III) trimeric building unit and 1,3,5-benzenetricarboxylate led to the powdered solid MIL-100. Simulations provided a crystal structure solution, which matched the experimental powder XRD pattern. This unique simulation/diffraction combination allowed the structure determination of a giant-pore solid with a zeotype architecture, built up from hybrid supertetrahedra (see picture). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z460592_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Design and synthesis of a novel peptide β-turn mimetic (1988)

The stereospecific synthesis of the novel spirocyclic unit (7), and its use in the construction by solid phase methods, of a conformationally locked analogue of the immunodominant nonapeptide (1) is described.
Application of Vehicle Telematic System in Fuzzy-Based HEV Control (2008)

In this paper, application of the vehicle telematic system in the design of an intelligent HEV control strategy is presented. The system employs a genetic-fuzzy controller that considers the influence of traffic condition on the controller parameters. The proposed intelligent controller is tuned by the traffic data received from the telematic information systems. For this purpose, the concept of the driving cycle is introduced to characterize the driving conditions by several traffic conditions. Accordingly, the application of telematics information for adaptation of the HEV fuzzy-based control system is explained. Finally, simulation results are presented to show the effectiveness of the suggested approach.
Polyaniline and poly(<i>N</i>-vinylcarbazole) blends as anode for blue light-emitting diodes (1999)

Polyaniline and poly(N-vinylcarbazole) (PANI:PVK) blends are introduced as an anode, and the advantages are demonstrated for organic light-emitting diodes (LEDs). Compared to the usual PANI network electrodes, use of the blend allows for simpler fabrication and provides a better planarized surface, especially for the device with vapor-deposited emitting layer. PANI is not usually used for blue LEDs because of its strong light absorption in the deep-blue spectral region. This problem is practically solved by the use of the blend.
MIC: Mutual Information based hierarchical Clustering (2008)

Clustering is a concept used in a huge variety of applications. We review a conceptually very simple algorithm for hierarchical clustering called in the following the {\it mutual information clustering} (MIC) algorithm. It uses mutual information (MI) as a similarity measure and exploits its grouping property: The MI between three objects X, Y, and Z is equal to the sum of the MI between X and Y, plus the MI between Z and the combined object (XY). We use MIC both in the Shannon (probabilistic) version of information theory, where the "objects" are probability distributions represented by random samples, and in the Kolmogorov (algorithmic) version, where the "objects" are symbol sequences. We apply our method to the construction of phylogenetic trees from mitochondrial DNA sequences and we reconstruct the fetal ECG from the output of independent components analysis (ICA) applied to the ECG of a pregnant woman.
Synthesis and Characterization of Carbohydrate-Linked Murine Monoclonal Antibody K20-human Serum Albumin Conjugates (1994)

Efficacy of antibody mediated targeting depends on retention of immunoreactivity in conjugates. Retention can be improved by site-specific linkage of drugs or drug-loaded carriers to residues that are located well away from the antigen-binding sites. In this study we describe the site-specific linkage of a potential drug carrier, human serum albumin (HSA), to the carbohydrate residues in Dal K20, a murine IgG1 monoclonal antibody (mAb) against human renal cell carcinoma, using disulfide exchange between 3-(2-pyridyldithio)propionic acid succinimidyl ester (SPDP)-derivatized HSA and 11-[[3-(2-pyridyldithio)propionyl]amino]undecanoic acid hydrazide (AUPDP)-derivatized mAb Dal K20. AUPDP gave a higher yield of the conjugate than a functionally analogous 3-(2-pyridyldithio)propionic acid hydrazide (HPDP), suggesting that the extra length of the former facilitated the linkage. The conjugates were found to be unstable without reduction of the hydrazone linkage using sodium cyanoborohydride. Stabilized 1:1 HSA:K20 carbohydrate-linked conjugates were isolated and compared with non-site-specific 1:1 conjugates in which HSA was conjugated to amino groups in mAb Dal K20. The yield and stability of the two conjugates were comparable, but the site-specific conjugate was found to retain three times more antibody activity than the non-site-specific conjugate.
Effectiveness of montelukast in modulation of filaggrin mutation 2282del4 in atopic dermatitis Egyptian patients (2014)

A Validated Comparitative LC and Ratio First Derivative Spectrophotometric Method for the Simultaneous Determination of Levocetrizine dihydrochloride and Montelukast sodium in Bulk and Pharmaceutical dosage formsR. Swethan Babu, K. Anirudha Bharadwaj, N.C Arjun, Nagaraj, Venkatesh Prasad
Rapid quantitative microenzyme-linked immunosorbent assay for tetanus antibodies (1983)

A rapid quantitative microenzyme-linked immunosorbent assay for the detection of immunoglobulin G antibodies to tetanus toxoid is described. The assay is performed in 2.5 h and detects antibody levels of between 0.1 and 6 U/ml. Quantitation of the antibody concentration is unique in that multiple serum dilutions are tested on a single patient, the results are plotted as an antibody dilution curve, and the area under the curve is integrated for a final concentration. Tests for immune status on sera from 77 individuals demonstrated tetanus antibody concentrations of greater than or equal to 0.1 U/ml in 92% of a pediatric group and 62% of an adult group. The microenzyme-linked immunosorbent assay procedure is reproducible and is useful for the determination of immune status and immunization response.
[An oligonucleotide microarray for detection and discrimination of orthopoxviruses based on oligonucleotide sequences of two viral genes]. (2006)

An oligonucleotide microarray for detection and identification of orthopoxviruses was developed. Genus specific and orthopoxvirus species-specific regions of the genes encoding chemokine binding and alpha/beta-interferon binding proteins were used as a target. The developed microarray allows the variola, monkeypox, cowpox, vaccinia, camel-pox and ectromelia (mousepox) viruses to be distinguished with a high degree of reliability.
Client Privacy and Social Work: A Comparison By Agency Function (1983)

This study examines the effect of agency function or purpose on the handling of client privacy issues in social work agencies. Practitioners working in public and private agencies were compared. The data revealed that, more than those in private agencies, social workers in public agencies: (1) thought that their work would be more affected if they could not rely on outside sources for information about clients; (2) were more often requested to supply information about clients to outside sources; and (3) were more likely to reveal information about clients as a form of ethical dilemma resolution. It is suggested that compliance from clients is the primary social reward sought by practitioners in public agencies and that client information is used as an instrument of power in obtaining it. Practitioners in private agencies, on the other hand, seek different social rewards and tend to be more protective of client privacy.
Tumor suppressive activity of a variant isoform of manganese superoxide dismutase released by a human liposarcoma cell line (2006)

A cell line derived from a pleiomorphic liposarcoma, named LSA, was previously reported to secrete (a) factor(s) exhibiting oncotoxic properties. The present article describes the isolation, purification and sequence analysis of a protein released by LSA cells into conditioned culture medium. This protein proved to be a variant isoform of manganese superoxide dismutase (MnSOD), hence its designation as LSA-type-MnSOD. This LSA-type-SOD differed from conventional SODs in its secretion by producer cells, contrasting with the normal localization of SODs in the mitochondrial matrix. Interestingly, during the protein purification process, LSA-type-SOD cosegregated with a cytotoxic activity directed against a number of tumor cell lines, as determined under in vitro conditions. This cytopathic effect was most likely due to LSA-type-SOD, since it could be fully reproduced using recombinant SOD that was expressed from cDNA clones isolated from LSA cells mRNA preparations and henceforth designated L-rSOD. In addition to its manifestation in cell lines kept in tissue culture, the oncotoxicity of LSA-type-SOD was further reflected in a remarkable capacity of this protein for suppression of mammary tumors in Balb-C-FR(III) mice. Animals subcutaneously injected with L-rSOD in the tumor area showed a complete disruption of established mammary carcinomas, as monitored by nuclear magnetic resonance (NMR) scanning. Moreover, metastatic spreading, which was readily detected in the control group, was suppressed in the treated animals. Altogether these data suggest that LSA-type-SOD interferes with survival and spreading of neoplastically transformed cells and deserves to be future validated as a therapeutic agent against cancer, either alone or in combination with conventional treatments.
Effect of the Extrusion Process on the Bactericidal Performance of Biocidal Polypropylene Catheters (2012)

This work concerns polypropylene biocidal catheters that incorporate the triclosan molecule. Many studies have applied triclosan as a bactericidal agent in the polymeric matrix but without considering the effect of processing on the biocidal properties. Using the optimal temperature and shear rate during the extrusion process can promote the best microbiological response for a biocidal catheter. Catheters were processed using a linear extruder while systematically varying the triclosan content, processing temperature and screw velocity. A diffusion test in agar and an evaluation of the chemical structure of the polypropylene and triclosan using FTIR were used to characterize the bactericidal properties.
HNE‐dependent molecular damage in diabetic nephropathy and its possible prevention by N‐acetyl‐cysteine and oxerutin (2005)

Accumulation of Advanced Lipoxidation End-products (ALE), such as MDA- and HNE-protein adducts, and Advanced Glycation End-products, such as carboxymethyl-lysine (CML), are probably involved in the development of diabetic nephropathy. In this study the effect of some antioxidant treatments (oxerutin, N-acetylcysteine, taurine and N-acetylcysteine+taurine) on kidney lipoxidative damage has been evaluated by immunohistochemistry in streptozotocined rats. Diabetic rats showed marked glomerular positivity for ALE, while the samples from Control rats were negative. All treatments except taurine were able to protect the glomeruli from ALE accumulation; the failure of taurine may be due to residual oxidative properties of its derivatives. These data are consistent with those of our previous study, which showed that all the antioxidants used except taurine protected the glomeruli from diabetes-induced enlargement, increased apoptotic rate, decreased cell density and CML accumulation. These data attest to a role of glycoxidative and lipoxidative damage in diabetes-dependent damage of the kidney, and indicate that specific antioxidants can prevent or attenuate diabetic nephropathy.
Molecular characterization of microbial communities in fault‐bordered aquifers in the Miocene formation of northernmost Japan (2006)

ABSTRACT We investigated the diversity and distribution of archaeal and bacterial 16S rRNA gene sequences in deep aquifers of mid‐ to late Miocene hard shale located in the northernmost region of the Japanese archipelago. A major fault in the north‐west–south‐east (NW–SE) direction runs across the studied area. We collected three groundwater samples from boreholes on the south‐west (SW) side of the fault at depths of 296, 374 and 625 m below ground level (m.b.g.l.) and one sample from the north‐east (NE) side of the fault at a depth of 458 m.b.g.l. The groundwater samples were observed to be neutral and weakly saline. The total microbial counts after staining with acridine orange were in the order 10 5 −10 6 cells mL −1 and 10 3 cells mL −1 in the aquifers to the SW and to the NE of the fault, respectively. A total of 407 archaeal and bacterial 16S rRNA gene sequences (204 and 203 sequences, respectively) were determined for clone libraries constructed from all groundwater samples. Phylogenetic analyses showed that the libraries constructed from the SW aquifers were generally coherent but considerably different from those constructed from the NE aquifer. All of the archaeal clone libraries from the SW aquifers were predominated by a single sequence closely related to the archaeon Methanoculleus chikugoensis , and the corresponding bacterial libraries were mostly predominated by the sequences related to Bacteroidetes, Firmicutes and δ‐Proteobacteria. In contrast, the libraries from the NE aquifer were dominated by uncultured environmental archaeal clones with no methanogen sequences and by β‐proteobacterial clones with no sequences related to Bacteroidetes and δ‐Proteobacteria. Hence, the possible coexistence of methanogens and sulphate reducers in Horonobe deep borehole (HDB) on the SW side is suggested, particularly in HDB‐6 (374 m.b.g.l.). Moreover, these organisms might play an important geochemical role in the groundwater obtained from the aquifers.
High-gain on-chip antennas for LSI intra-/inter-chip wireless interconnection (2009)

A wireless interconnection technology using on-chip antennas has been proposed for three dimensional packaging of LSI chips. The issues of on-chip antennas are extremely low gain due to lossy Si substrates. In this study, we developed a high gain on-chip antenna structure by thinning the Si substrate thickness and optimizing interposer thickness underlying the Si substrate. The transmission coefficient increased from −93 dB to −31 dB at the distance of 20 mm for inter-chip communication between 180 nm CMOS chips.
Intracellular Screening of a Peptide Library to Derive a Potent Peptide Inhibitor of α-Synuclein Aggregation (2015)

Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson disease (PD). Studies have focused largely on residues 71-82, yet most early-onset mutations are located between residues 46 and 53. A semirationally designed 209,952-member library based entirely on this region was constructed, containing all wild-type residues and changes associated with early-onset PD. Intracellular cell survival screening and growth competition isolated a 10-residue peptide antagonist that potently inhibits α-syn aggregation and associated toxicity at a 1:1 stoichiometry. This was verified using continuous growth measurements and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide cytotoxicity studies. Atomic force microscopy and circular dichroism on the same samples showed a random-coil structure and no oligomers. A new region of α-syn for inhibitor targeting has been highlighted, together with the approach of using a semirational design and intracellular screening. The peptides can then be used as candidates for modification in drugs capable of slowing or even preventing the onset of PD.
EndoCAS navigator platform: a common platform for computer and robotic assistance in minimally invasive surgery (2008)

We have successfully developed a system for computer-assisted technologies for use in laparoscopic surgery and demonstrated, by early clinical trials, that the introduction of these technologies in operative laparoscopy, even though they are not yet sufficiently accurate (from an engineering viewpoint) for surgical treatment of intra-abdominal disease, brings added benefits to the execution of interventions by surgeons and hence represents concrete on-going progress in interventional technology.
Excitation energy dependence of core-level x-ray-photoemission-spectra line shapes in metals (1975)

Creation of a deep localized hole in the process of x-ray photoemission from metals is followed by a drastic rearrangement of the surrounding electrons in the Fermi sea. This rearrangement in which low-energy electron-hole pairs are produced, in analogy with gas-phase atomic shake-up processes, gives rise to a low-energy tail in the hole spectral density with an integrable (Mahan) singularity at the energy corresponding to zero-energy pair production. When the usual (symmetric) broadening of the hole is included, the resulting hole line shape becomes a skew resonance, with the asymmetry indices growing with the strength of the electron-hole interaction. The case in which the hole potential is switched on instantaneously (the sudden or impulse limit) has been treated by Doniach and \ifmmode \check{S}\else \v{S}\fi{}unji\ifmmode \acute{c}\else \'{c}\fi{}. However, the potential switching-on time is a function of the speed at which the excited electron leaves the region of the hole. In this paper we calculate the skew line shapes for finite hole-creation times, going continuously from the adiabatic to sudden limits. The photoemission line shape, for a given hole state, varies smoothly from the symmetric result given in the adiabatic approximation to the asymmetric result of Doniach and \ifmmode \check{S}\else \v{S}\fi{}unji\ifmmode \acute{c}\else \'{c}\fi{} obtained in the sudden approximation, as the photon energy is increased above the photoionization threshold value.