gebhart/patrepeval huggingface dataset:
Una combinació de pronoms febles admissible (2003)

Objectives To evaluate angiographic patterns that may predict the success or failure of carotid artery balloon test occlusion (BTO) and single-photon emission computed tomography (SPECT) analysis for carotid sacrifice. Study Design This is a retrospective nonrandomized study. Study Setting Conducted at the University of California Davis Medical Center, Sacramento, California. Patients A total of 31 patients, ranging from 24 to 83 years of age, with a mean age of 61 years (22 men, 9 women) with head and neck cancer (26 patients), malignant glomus tumor (1 patient) or giant carotid aneurysms (4 patients) as possible candidates for surgical carotid artery sacrifice were evaluated from September 2005 to September 2012. Methods All patients underwent unilateral internal carotid artery balloon test occlusion with SPECT analysis (20 mCi technetium 99m-hexamethyl propyleneamine oxime [HMPAO]) imaging before and during carotid occlusion. Carotid angiography with carotid cross-compression (manual compression of the cervical artery contralateral to the side of contrast injection) was used to analyze filling through the anterior communicating artery to the contralateral hemisphere. Intervention The balloon occlusion was terminated in two patients because of deterioration of the neurologic exam. Main Outcome Measures All patients who passed the neurologic examination during BTO and also passed the SPECT occlusive study underwent successful carotid sacrifice without neurologic sequelae. Patients failing the occlusive neurologic examination and/or the SPECT study elected chemoradiation, with the exception of one patient who underwent a successful carotid bypass graft and carotid resection. Results The success of carotid sacrifice in patients passing both the occlusive test and the SPECT analysis for carotid sacrifice was 100%. Three patients failed both the BTO and the SPECT, with two demonstrating no anterior circulation cross-fill, but one showed some cross-fill. Six additional patients passed the BTO but failed the SPECT, with poor cross-fill in five patients. In addition, three patients who had excellent cross-fill through the anterior communicating artery to the contralateral hemisphere failed the SPECT examination in two cases and failed both tests in another case.
A Formal Study of Shot Boundary Detection (2007)

This paper conducts a formal study of the shot boundary detection problem. First, a general formal framework of shot boundary detection techniques is proposed. Three critical techniques, i.e., the representation of visual content, the construction of continuity signal and the classification of continuity values, are identified and formulated in the perspective of pattern recognition. Meanwhile, the major challenges to the framework are identified. Second, a comprehensive review of the existing approaches is conducted. The representative approaches are categorized and compared according to their roles in the formal framework. Based on the comparison of the existing approaches, optimal criteria for each module of the framework are discussed, which will provide practical guide for developing novel methods. Third, with all the above issues considered, we present a unified shot boundary detection system based on graph partition model. Extensive experiments are carried out on the platform of TRECVID. The experiments not only verify the optimal criteria discussed above, but also show that the proposed approach is among the best in the evaluation of TRECVID 2005. Finally, we conclude the paper and present some further discussions on what shot boundary detection can learn from other related fields
Co-Treatment of PTH With Osteoprotegerin or Alendronate Increases Its Anabolic Effect on the Skeleton of Oophorectomized Mice (2006)

These studies show that the highly potent anti-catabolic OPG can produce dramatic increases in BMD and bone strength; that the temporal pattern of activity of bone formation and resorption modulators may have major influence on net skeletal accrual; and that, depending on timing, inhibition of osteoclastic activity may markedly augment the anabolic action of PTH.
1,3‐Diaryl‐2‐propenones and 2‐Benzylidene‐1,3‐indandiones: A Quest for Compounds Displaying Greater Toxicity to Neoplasms than Normal Cells (2010)

A series of 1,3-diaryl-2-propenones 2a-j and analogous 2-benzylidene-1,3-indandiones 3a-j were evaluated against various neoplasms and normal cells. In general, greater cytotoxic potencies and selective toxicity to human malignant cells were observed by the compounds in series 2 rather than 3. In particular, 2i emerged as a lead molecule having an average CC(50) figure of 8.6 µM and a selective index value of 18. Various physicochemical features of 2a-j were correlated with the cytotoxic potencies to neoplastic cell lines which provide guidelines for expansion of this series of compounds. The enone 2i induced internucleosomal DNA fragmentation and activated caspase-3 in HL-60 cells suggesting that one of the ways in which the cytotoxicity of the compounds in series 2 is mediated towards some of the cell lines used in this study is by apoptosis. Neurotoxicity in mice was generally lower in series 2 than 3a-j.
Fairness and Throughput Analysis for Generalized Proportional Fair Frequency Scheduling in OFDMA (2005)

In this paper, a generalized proportional fair (GPF) scheduling algorithm is presented, which allows tweaking the trade-off between fairness and throughput performance for best effort traffic in a cellular downlink scenario. The GPF is extended to frequency scheduling in an OFDMA system by performing dynamic channel allocation on a subband basis including link adaptation by adaptive modulation and coding. In this way, multiuser diversity can be utilized in time domain - as for CDMA - and in frequency domain. Compared to a system without frequency scheduling, this increases the system throughput and yields an improved fairness with respect to the allocated resources and with respect to the achieved data-rate per user. OFDMA system level simulations are carried out in order to analyze short/long-term fairness, multiuser diversity gain and system throughput of various GPF configurations with and without applying frequency scheduling.
Researchers Vie to Achieve a Quantum-Dot Laser (1996)

If semiconductor quantum-well lasers are so successful, shouldn't quantum-wire or quantum-dot lasers be even better? That's a question that many researchers have set out to answer. Quantum wells confine the charge carriers in one dimension; wires confine them in two; and dots, in three. (Quantum dots are clusters of semiconductor material with a few thousand atoms.) As a result of their confinement, the charge carriers occupy discrete energy levels similar to those of electrons in an atom. Energy pumped into the system raises the charge carriers from one energy level to the next; none of it goes to random motion, because there are no other degrees of freedom. Thus, one expects any lasing from the dots to occur with high efficiency and at lower threshold current than in either quantum wells or quantum wires.
Variable reaction pathways for the action of polysulfide on Michael acceptors (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVariable reaction pathways for the action of polysulfide on Michael acceptorsRobert T. LaLonde, Robert A. Florence, Benjamin A. Horenstein, Richard C. Fritz, Linda Silveira, Jon Clardy, and Bala S. KrishnanCite this: J. Org. Chem. 1985, 50, 1, 85–91Publication Date (Print):January 1, 1985Publication History Published online1 May 2002Published inissue 1 January 1985https://pubs.acs.org/doi/10.1021/jo00201a017https://doi.org/10.1021/jo00201a017research-articleACS PublicationsRequest reuse permissionsArticle Views355Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
GUI Software Fault Localization Using N-gram Analysis (2011)

Graphical User Interfaces (GUIs) have become an important and accepted way of interacting with today's software. Fault localization is considered to be one of the most expensive program debugging activities. This paper presents a fault localization technique designed for GUI software. Unlike traditional software, GUI test cases usually are event sequences and each individual event has a unique corresponding event handler. We apply data mining techniques to the event sequences and their output data in terms of failure detections collected in the testing phase to rank the fault proneness of the event handlers for fault localization. Our method applies N-gram analysis to rank the event handlers of GUI programs and data collected from case studies on four real life GUI programs demonstrate the effectiveness of the proposed technique.
On the Sintering of the TiNx-Ni Binary Mixed Powder Compacts (1979)

Sintering characteristics of TiNx-Ni mixed powder compacts were studied by heating them in gas atmospheres of nitrogen, hydrogen or argon, or in vacuum.The shrinkage during sintering was considerably disturbed by the liberated nitrogen gas from the compacts, whereas in lower value for x of TiNx, the gas diffused into TiN, grains up to TiN0.99 without denitrification. So that the shrinkage was remarkably promoted not only in vacuum, but also in hydrogen and argon. While, the nitrogen atmosphere hindered the shrinkage.The Ni concentration and x value in formula TiNx showing the maximum sintered density in the sintering condition at 1500°C for 60min. were approximately 15 wt% and 0.8, respectively.
Resistance Spot Welding and In-Process Heat Treatment of Hot Stamped Boron Steel (2016)

Escalating environmental concerns have prompted efforts to reduce vehicle weight and carbon emissions, resulting in increased application of advanced high strength steels (AHSS). 22MnB5 hot stamping grade AHSS, namely USIBOR 1500P, provide high strength to weight ratio allowing sheet thickness reduction to decrease weight, while maintaining high safety characteristics. \nResistance spot welding (RSW) has been the predominant welding process for automotive assemblies. Welding hot-stamping AHSS has introduced new challenges for achieving acceptable welds. The added alloying elements and high hardenability characteristics resulting in low weldability and weld toughness complicates this initiative. The current study examines the effects of in-process weld tempering with secondary current pulse has on the weld toughness during RSW of USIBOR steels. \nRSW and weld tempering were tested on USIBOR at two different surface conditions; as-delivered and hot-stamped. Joint performance properties, micro-hardness map profiles, and failure modes of welds for both tempered and non-tempered conditions are detailed. Furthermore, a relationship between resulting joint performance and microstructural evolution is produced.\nThe objective of this work is to optimize in-process tempering parameters, analyze metallurgical evolution of the weldments, and compare the effects on mechanical performance for both tempered and non-tempered welds.
DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins (2016)

Microalgae are versatile organisms capable of converting CO2, H2O, and sunlight into fuel and chemicals for domestic and industrial consumption. Thus, genetic modifications of microalgae for enhancing photosynthetic productivity, and biomass and bio-products generation are crucial for both academic and industrial applications. However, targeted mutagenesis in microalgae with CRISPR-Cas9 is limited. Here we report, a one-step transformation of Chlamydomonas reinhardtii by the DNA-free CRISPR-Cas9 method rather than plasmids that encode Cas9 and guide RNAs. Outcome was the sequential CpFTSY and ZEP two-gene knockout and the generation of a strain constitutively producing zeaxanthin and showing improved photosynthetic productivity.
Nucleolar Protein B23 Stimulates Nuclear Import of the HIV-1 Rev Protein and NLS-Conjugated Albumin (1997)

Nucleolar phosphoprotein B23 is a putative ribosome assembly factor with a relatively high affinity for peptides containing sequences of nuclear localization signals (NLSs) of the SV40 T-antigen type [Szebeni, A., Herrera, J. E., & Olson, O. J. (1995) Biochemistry 34, 8037-8042]. The effects of protein B23 on nuclear import were determined by an in vitro assay [Dean, D. A., & Kasamatsu, H. (1994) J. Biol. Chem. 269, 4910-4916] using NLS peptide-conjugated bovine serum albumin (NLS-BSA) or the HIV-1 Rev protein as substrates for import into isolated rat liver nuclei. The import was ATP-dependent and inhibited by wheat germ agglutinin or by an antibody against p97, a component of the nuclear import system. The rate of import of either substrate was increased if protein B23 was added to the incubation medium. Similar enhancements of import were seen with both isoforms (B23.1 and B23.2). The stimulatory effect on Rev protein import was saturable with maximum stimulation (2-3-fold) at a molar ratio of protein B23:Rev of approximately 1:1. Phosphorylation of protein B23.1 by casein kinase II produced an additional doubling of the import rate. This effect was not seen if protein B23.1 was phosphorylated with a cdc2 type protein kinase. Mutant forms of protein B23.1 in which the nuclear localization signal was either deleted or altered did not stimulate import of the substrates. These results suggest that protein B23 plays a role as an accessory factor in the nuclear import of the NLS-containing proteins and that phosphorylation at sites in the highly acidic segments of the protein enhances the stimulatory effect.
3′-C-Branched Thymidine 5′-Triphosphates: Synthesis, Application, and Coupling with Near-Infrared Oxazine Fluorescent Dye (2000)

The synthesis of the novel class of 3′-C-modified thymidine nucleotides is described. The aldehyde 1 was converted into the derivatives 5, 7, and 10 that differ in the length of the carbon chain. One-pot phosphorylation gave the corresponding triphosphates 11, 12, 13. The 3′-C-(2-azidoethyl)-3′-deoxythymidine 5′-triphosphate 13 was reduced by triphenylphosphine to the amino nucleotide 14. All amino nucleotides have been dye-labelled at the aliphatic amino group with the oxazine dye JA242. All triphosphates were tested as terminators in DNA-sequencing reactions.
Temperature dependence of chromatic dispersion in various types of optical fibers (2002)

Temperature dependence of chromatic dispersion is examined for various types of fibers. Its coefficient is found strongly dependent on dispersion slope, indicating that low dispersion slope transmission lines are desirable for future high bit-rate transmission.
Clenbuterol, a <i>β</i>-Adrenoceptor Agonist, Increases Relative Muscle Strength in Orthopaedic Patients (1993)

1. The sympathomimetic agent clenbuterol has a muscle-specific anabolic effect in normal and wasted muscles from animals. This trial was designed to examine the effect of the drug on the recovery of muscle strength and area after open medial meniscectomy. 2. A double-blind, completely randomized, placebo-controlled study was carried out on 20 healthy male patients. Muscle strength and cross-sectional area were determined before and after surgery. Patients were treated with drug or placebo for 4 weeks postoperatively and there was a 2 week washout period. 3. The results suggest that, in the operated leg, clenbuterol treatment is associated with a more rapid rehabilitation of strength in knee extensor muscles; in the unoperated leg, knee extensor strength increased above the initial values after 6 weeks (P = 0.01). However, in terms of absolute strength the differences were not significant between the two groups. 4. It is concluded that the data lend support to the proposition that clenbuterol has therapeutic potential in the treatment of muscle-wasting conditions.
A megawatt solid-state modulator for high repetition rate pulse generation (2016)

A novel solid-state modulator capable of generating rapid consecutive power pulses is constructed to facilitate experiments on plasma interaction with high power microwave pulses. The modulator is designed to output a 100 kHz tone burst, which consists of up to 10 pulses, each with 1 μs duration and 1 MW peak power. The pulses are formed by discharging a total of 480 μF capacitors through 24 synchronized MOSFETs and 6 step-up transformers. The highly modular design, as a replacement of an old single-pulse version used in earlier experiments which employs a pulse forming network, brings great flexibility and wide potential to its application. A systematic cost-effectiveness analysis is also presented.
The Use of Contrast-Detail-Dose Evaluation of Image Quality in a Computed Tomographic Scanner (1979)

Limiting-perception measurements of hole patterns in computed tomography reconstructions of a low-contrast phantom are used to generate contrast -- detail -- dose diagrams for various contrasts, hole diameters, dose, and system modulation transfer functions (MTF). These curves are then divided into MTF-dominated, transition, and noise-dominated regions. The low-contrast perceptibility and image noise are parameterized and compared. A limiting-perception factor is difined and is shown to be nearly independent of contrast, hole diameter, dose, and MTF in the noise-dominated region.
A Prioritized MAC Protocol for Multihop, Event-driven Wireless Sensor Networks (2006)

This paper presents a new Prioritized medium access control protocol (PSIFT) that improves the performance of event-driven wireless sensor networks by suppressing the redundant reports of sensor nodes in proximity. This suppression of similar reports results in low collision probability, shorter delay and accurate detection of events by the sink. PSIFT is a CSMA-based MAC protocol that provides traffic differentiation by varying the inter frame space and contention window size for each traffic class. We also introduce the new report suppression mechanism based on the broadcast nature of wireless transmission in PSIFT. This mechanism works very efficiently in large-scale, event-driven wireless sensor networks. Simulation results show that the new PSIFT MAC protocol can bring significant improvement in delay performance of the networks. When the sensing range grows up to transmission range, PSIFT can reduce the latency as much as three times in delivering reports as compared to the existing IEEE802.11 MAC protocol.
High-density interconnection using photosensitive polyimide and electroplated copper conductor lines (1990)

Multilayer high-density thin-film interconnection structures with a wiring density of up to 1000 lines per inch per signal layer were fabricated using a photosensitive polyimide as dielectric and electroplated copper conductor lines. Lithographic considerations associated with the patterning of high-aspect-ratio (>1.0) polyimide precursor features and their distortions during high-temperature annealing steps were investigated. An anisotropic shrinkage causing inward skewing of the feature profiles was observed. This phenomenon strongly depended on the UV exposure conditions and appears to be related to nonuniformity in the precursor cross-link density. The present approach of electroplating small-geometry copper features in patterned polyimide trenches provides excellent planarization in interconnect structures containing high-aspect-ratio features. Transmission characteristics of high-frequency signals in these lossy interconnect lines showed minimal degradation in the pulse shape or attenuation in the pulse amplitude. A high-density memory module, consisting of two orthogonal X-Y layers of 25- mu m-wide copper lines fabricated at a pitch of 80 mu m over a silicon substrate, was fabricated. The two layers of conductor lines were interconnected with electroplated copper vias. Epoxy-based die-bonding and gold wire bonding techniques were used for the assembly of the populated module in a metal flat pack. Integrity of the fabricated copper-polyimide multichip modules under moisture and thermal stressing conditions was demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Baby Care System Design for Multi-Sensor Applications (2019)

Since a baby will be taken care of by the health care worker after the birth, and each health care worker is taking care of multiple babies, it is necessary to regularly understand the physical condition of each baby and make a record, in order to reduce the workload of the health care workers. Therefore, for this issue, the Microchip 16bits architecture dsPIC30F4011 is adopted as the control core in this study to construct a “low-cost, high-efficiency, intelligent baby care system.” Using the control advantages of a microcontroller, with the relevant control and sensing circuits designed by the user, through measuring various physiological signals of the baby, and constructing a monitoring screen of the LabView graphical language in the computer interface, the wireless transmission method is used for making a remote wireless connection with the care vehicle to facilitate the monitoring by the health care worker. In addition, the motor can be driven to drive the ambulance to swing back and forth to achieve the effect of comforting the baby, and the workload of the health care worker can be greatly reduced, so that it can be most efficiently applied to human beings.
The Application of Drug-Disease and Clinical Utility Models in the Design of AWARD-5: an Adaptive Seamless Phase 2/3 Study (2013)

NoDM-Placebo NoDM-Sibutramine NoDM-Rimonabant NoDM-Dexfenfluramine NoDM-Lorcaserin NoDM-Qsymia T2DM-Placebo T2DM-Sibutramine T2DM-Exenatide T2DM-Exen LAR T2DM-Lixisenatide T2DM-Liraglutide T2DM-Taspoglutide T2DM-Albiglutide T2DM-Lorcaserin T2DM-Qsymia
Amplification of human short tandem repeats from medieval teeth and bone samples. (1996)

The suitability of typing hypervariable DNA loci for the genetic analysis of prehistoric populations is demonstrated for the first time. Alleles of the human short tandem repeat locus VWA31/A have been amplified from ancient teeth and bone samples derived from an early medieval burial site at Weingarten, Germany, using the polymerase chain reaction. The DNA results for 76 individuals reveal remarkable similarity of the allelic frequencies between the past and modern populations. A surplus of apparent homozygotes in the ancient population is most likely due to a stochastic problem of amplification of degraded DNA. Therefore technical obstacles for the application to ancient DNA were evaluated. The substantial perspectives of using microsatellite typing for the analysis of heritable diseases, determination of relatedness, and establishment of genealogies in prehistoric populations are outlined.