gebhart/patrepeval huggingface dataset:
Digital Mobile Fronthaul Based on Delta–Sigma Modulation for 32 LTE Carrier Aggregation and FBMC Signals (2017)

We first experimentally demonstrated a digital mobile fronthaul (MFH) architecture using delta–sigma modulation as the new digitization interface to replace the conventional common public radio interface (CPRI). Both one-bit and two-bit delta–sigma modulations were demonstrated, and the digitized signals were transmitted over on–off keying (OOK) or 4-level pulse-amplitude-modulation (PAM4) optical intensity modulation-direct detection (IM-DD) links. 32 LTE component carriers (CCs) were digitized and transmitted over a 25-km single-λ 10-Gbaud OOK/PAM4 link, so that 32 LTE carrier aggregation (CA) specified by 3GPP release 13 can be supported. Compared with the conventional digitization interface based on CPRI, the fronthaul capacity is increased by four times. Error vector magnitude (EVM) less than 5% or 2.1% for all LTE CCs was obtained using one-bit and two-bit delta–sigma modulators, so that high-order modulations (256QAM/1024QAM) can be supported. As a waveform-agnostic digitization interface, delta–sigma modulation can digitize not only 4G-LTE but also 5G waveforms, and its 5G compatibility was verified by filter-bank-multicarrier (FBMC) signals. The tolerance to bit error ratio (BER) of the proposed delta–sigma modulation-based digital MFH was evaluated, and no significant EVM degradation was observed for BER up to 3×10−5. A comparison with analog MFH reveals that the proposed digital MFH based on delta–sigma modulation can offer improved resilience against noise and nonlinear impairments, and it increases the fronthaul capacity by four times compared with the conventional CPRI-based digital MFH without significant EVM penalty.
Adaptive tactical navigation denouement (2002)

An overview is given of the adaptive tactical navigation (ATN) system, a laboratory prototype of a knowledge-based system which provides navigation system management and decision aiding for the next generation of tactical aircraft. The purpose of the ATN system is to manage a future multisensor navigation suite, dynamically selecting the best source of navigation information based on the current mission phase, mission goals, threat environment, and equipment availability. ATN encompasses functions as diverse as sensor data interpretation, diagnosis, and planning. The ATN system was developed and evaluated in a laboratory environment, followed by rehosting and evaluation in an F-16 cockpit simulation dome environment. Evaluation results indicate that operational deployment of a system using ATN technology would result in optimal use of navigation resources, reduced pilot workload, improved situational awareness, and intelligent navigation system failure detection and isolation. Collectively, these benefits provide significant improvement in mission effectiveness. Program results and lessons learned are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
PERFLUOROALKYLATION OF AROMATIC COMPOUNDS (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPERFLUOROALKYLATION OF AROMATIC COMPOUNDSGeorge V. D. TiersCite this: J. Am. Chem. Soc. 1960, 82, 20, 5513Publication Date (Print):October 1, 1960Publication History Published online1 May 2002Published inissue 1 October 1960https://pubs.acs.org/doi/10.1021/ja01505a059https://doi.org/10.1021/ja01505a059research-articleACS PublicationsRequest reuse permissionsArticle Views491Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An introduction to heart rate variability: methodological considerations and clinical applications (2015)

EDITORIAL article Front. Physiol., 25 February 2015Sec. Cardiac Electrophysiology Volume 6 - 2015 | https://doi.org/10.3389/fphys.2015.00055
High efficiency amplification and low threshold lasing at 0.8 µm in a thulium-doped fluorozircomate fiber (1992)

Monomode Tm-doped fluorozirconate fiber can exhibit high gain amplification with pump and signal wavelengths both in the AlGaAs diode range. This is of great potential interest for local area networks operating near 0.8µm, where transmitters and receivers are significantly less expensive than those at 1.3 or 1.5µm. In this paper we describe a Tm3+-doped fluorozirconate fiber acting when pumped at 785 nm both as an amplifier giving 20-dB gain at 806 nm and as a fiber laser.
Clinical pharmacology of 5-iodo-2′-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation (1985)

We describe the clinical pharmacology and metabolism of 5-iodo-2'-deoxyuridine (IdUrd) during and after a 12-hour infusion. The kinetics of IdUrd were linear between 250 and 1200 mg/m2. The plasma IdUrd concentration reached steady state in less than 1 hour. Total body clearance of IdUrd was 750 ml/min/m2 and the disappearance t1/2 at the end of the infusion was less than 5 minutes. The primary metabolite, 5-iodouracil (IUra), did not reach steady state during the infusion. At the end of the 1200 mg/m2 infusion, the maximum plasma IUra concentration was 100 mumol/L, or about 10 times the simultaneous IdUrd plasma concentration. During the infusion there was at least a fifty- to 100-fold increase in uracil and thymine plasma concentrations. After the infusion, IUra disappearance from plasma was nonlinear, with an apparent Michaelis constant of 30 mumol/L. Plasma uracil and thymine levels slowly decreased after the IdUrd infusion until IUra fell to less than 30 mumol/L. There was subsequently a parallel and more rapid decrease in the plasma concentrations of uracil and thymine. Uridine, 2'-deoxyuridine, and thymidine plasma levels did not change significantly as a result of IdUrd therapy. These changes in endogenous pyrimidine pools are consistent with competitive inhibition of dihydrouracil dehydrogenase by IUra. An in vitro human bone marrow assay was used to determine the relative toxicity of IdUrd and IUra. Although exposure to IUra was tenfold higher than that to IdUrd, IdUrd was at least 100 times more cytotoxic to marrow cells.
Office-by-example: an integrated office system and database manager (1987)

Office-by-Example (OBE) is an integrated office information system that has been under development at IBM Research. OBE, an extension of Query-by-Example, supports various office features such as database tables, word processing, electronic mail, graphics, images, and so forth. These seemingly heterogeneous features are integrated through a language feature called example elements . Applications involving example elements are processed by the database manager, an integrated part of the OBE system. In this paper we describe the facilities and architecture of the OBE system and discuss the techniques for integrating heterogeneous objects.
The Agaricus bisporus pruA gene encodes a cytosolic delta 1-pyrroline-5-carboxylate dehydrogenase which is expressed in fruit bodies but not in gill tissue (1997)

A fortuitously cloned 3'-truncated cDNA encoding the Agaricus bisporus delta 1-pyrroline-5-carboxylate dehydrogenase was used to characterize the complete gene. The gene would encode a cytosolic polypeptide of 546 amino acids, and the basidiomycetous gene was evenly expressed in various parts of the mushroom except for the gills. No expression was detected in compost-grown mycelium. The steady-state mRNA level of the gene in the vegetative phase was determined on simple synthetic media and was two- to threefold higher with ammonium or proline as the sole nitrogen source compared to glutamate as the sole nitrogen source. Moreover, the steady-state mRNA level was not markedly influenced by addition of ammonium phosphate to proline- or glutamate-utilizing cultures. The results suggest that ammonium and the amino acids proline and glutamate are equally preferred nitrogen sources in this organism and are consistent with previous observations of H. M Kalisz, D.A. Wood, and D. Moore (Trans. Br. Mycol. Soc. 88:221-227, 1987) that A. bisporus continues to degrade protein and secrete ammonium even if ammonium and glucose are present in the culture medium.
Improving adherence to antiretroviral therapy (2005)

Antiretroviral therapy (ART) has transformed HIV infection into a treatable, chronic condition. However, the need to continue treatment for decades rather than years, calls for a long-term perspective of ART. Adherence to the regimen is essential for successful treatment and sustained viral control. Studies have indicated that at least 95% adherence to ART regimens is optimal. It has been demonstrated that a 10% higher level of adherence results in a 21% reduction in disease progression. The various factors affecting success of ART are social aspects like motivation to begin therapy, ability to adhere to therapy, lifestyle pattern, financial support, family support, pros and cons of starting therapy and pharmacological aspects like tolerability of the regimen, availability of the drugs. Also, the regimen's pill burden, dosing frequency, food requirements, convenience, toxicity and drug interaction profile compared with other regimens are to be considered before starting ART. The lack of trust between clinician and patient, active drug and alcohol use, active mental illness (e.g. depression), lack of patient education and inability of patients to identify their medications, lack of reliable access to primary medical care or medication are considered to be predictors of inadequate adherence. Interventions at various levels, viz. patient level, medication level, healthcare level and community level, boost adherence and overall outcome of ART.
Implicit Self-Regularization in Deep Neural Networks: Evidence from Random Matrix Theory and Implications for Learning (2018)

Random Matrix Theory (RMT) is applied to analyze weight matrices of Deep Neural Networks (DNNs), including both production quality, pre-trained models such as AlexNet and Inception, and smaller models trained from scratch, such as LeNet5 and a miniature-AlexNet. Empirical and theoretical results clearly indicate that the DNN training process itself implicitly implements a form of Self-Regularization. The empirical spectral density (ESD) of DNN layer matrices displays signatures of traditionally-regularized statistical models, even in the absence of exogenously specifying traditional forms of explicit regularization. Building on relatively recent results in RMT, most notably its extension to Universality classes of Heavy-Tailed matrices, we develop a theory to identify 5+1 Phases of Training, corresponding to increasing amounts of Implicit Self-Regularization. These phases can be observed during the training process as well as in the final learned DNNs. For smaller and/or older DNNs, this Implicit Self-Regularization is like traditional Tikhonov regularization, in that there is a "size scale" separating signal from noise. For state-of-the-art DNNs, however, we identify a novel form of Heavy-Tailed Self-Regularization, similar to the self-organization seen in the statistical physics of disordered systems. This results from correlations arising at all size scales, which arises implicitly due to the training process itself. This implicit Self-Regularization can depend strongly on the many knobs of the training process. By exploiting the generalization gap phenomena, we demonstrate that we can cause a small model to exhibit all 5+1 phases of training simply by changing the batch size. This demonstrates that---all else being equal---DNN optimization with larger batch sizes leads to less-well implicitly-regularized models, and it provides an explanation for the generalization gap phenomena.
Studies on immobilized fungal spores for microbial transformation of steroids: 11 α‐Hydroxylation of progesterone with immobilized spores of <i>Aspergillus ochraceus G8</i> on polyacrylamide gel and other matrices (1984)

Hydroxylation in the 11 alpha-position in the progesterone molecule employing immobilized spores of Aspergillus ochraceus strain No. G8 (CDRI catalogue No.) was achieved. For immobilization the activity of the spores was evaluated on a variety of matrices such as alginate beads, epoxy resin beads, polyacrylamide gel, and collagen. Spores entrapped in polyacrylamide gel were found to be the most active. Studies of various parameters, e.g. monomer content, cell loading capacity, optimum pH, temperature, and substrate concentration, were carried out on polyacrylamide gel. In polyacrylamide, the entrapped spores normal decay pattern, as indicated by loss of activity, was observed after four uses. At the end of 15 cycles, the residual activity was found to be 18% of the original. It was possible to regenerate the activity by incubating the preparation in a nutrient medium. The regenerated spores showed increasing rate of loss of activity upon recycling.
Development of the Sweep-Twist Adaptive Rotor (STAR) Blade (2010)

The Low Wind Speed Technology (LWST) project seeks to develop technology that will allow wind systems to provide reduced energy costs in regions where wind speeds average around 5.8 m/s, so-called low wind speed sites. As part of LWST, Sandia National Laboratories contracted with Knight & Carver to develop a sweep-twist adaptive blade to passively reduce operating loads, thereby allowing for a larger, more productive rotor and ultimately reducing the cost-of-energy. After design and fabrication of a 27.1 m STAR blade, static and fatigue laboratory tests were successfully carried out. Full flight testing on a Zond 750 test turbine verified the predicted performance and operating loads. The STAR blade exceeded the project goal of improving annual energy capture over the baseline by producing 10-12 % more energy.
The space requirements of indexing under perspective projections (1996)

Object recognition systems can be made more efficient through the use of table lookup to match features. The cost of this indexing process depends on the space required to represent groups of model features in such a lookup table. We determine the space required to perform indexing of arbitrary sets of 3D model points for lookup from a single 2D image formed under perspective projection. We show that in this case, one must use a 3D surface to represent model groups, and we provide an analytic description of such a surface. This is in contrast to the cases of scaled-orthographic or affine projection, in which only a 2D surface is required to represent a group of model features. This demonstrates a fundamental way in which the recognition of objects under perspective projection is more complex than is recognition under other projection models.
Administration of anti-Reg I and anti-PAPII antibodies worsens pancreatitis. (2009)

Administration of anti-Reg/PAP antibody worsened taurocholate-induced organ specific pancreatitis. These data suggest that the Reg family of proteins is protective in acute pancreatitis.
In Situ Proximity Ligation Assay for Microscopy and Flow Cytometry (2011)

The ability to study proteins and protein interactions inside cells and tissues is important for elucidating how cells function in health and disease. The in situ proximity ligation assay (in situ PLA) presented here can be used to visualize proteins, protein-protein interactions, and post-translational modifications in cells and tissues. The method is based upon the use of antibodies that target the proteins involved in an interaction; hence, the method has the advantage that it can be used in clinical specimens, providing localized, quantifiable single molecule detection in single cells. This unit describes how in situ PLA can be used with fluorescence microscopy and flow cytometry to study proteins (obtaining high sensitivity and specificity of detection) and protein interactions. It also includes information on expected results and information on how to troubleshoot the assay.
Platycodon grandiflorum modifies adipokines and the glucose uptake in high-fat diet in mice and L6 muscle cells (2012)

We conclude that PGE may improve obesity in mice fed an HFD and glucose uptake in L6 muscle cells by modifying adipokines, and could offer clinical benefits as a supplement to treat obesity and diabetes.
An Arrestant and Feeding Stimulant for the Boll Weevil in Water Extracts of Cotton-Plant Parts1 (1963)

A powerful arrestant and feeding stimulant for boll weevils (Anthonomus grandis Boheman) was found to exist in water extracts or all cotton-plant parts and square components investigated. A biological assay method was developed by utilizing agar plugs impregnated with the extract and wrapped with filter paper, to determine quantitatively the concentration of the arrestant. All the cotton plant parts investigated were found to contain the arrestant in sufficient concentration for bioassay. Flowers at the stage or anthesis and whole squares contained the highest. In the square, the exterior component (calyx) contained the highest but the amount progressively decreased interiorly, with the lowest in the ovary. Presence of the arrestant and feeding stimulant in germinated seed or seedlings indicated they could be used as screening agents in host-plant resistance programs, obviating need for fruiting plants. Correlation between weevil feeding response and concentration was almost direct, with the bottom limit at 10,000 p.p.m. Agar plugs with small amounts of water extract from squares elicited a much higher feeding response than a commonly used artificial adult-weevil diet.
Role of supplementary material in biomedical journal articles: surveys of authors, reviewers and readers (2018)

NCT02961036.
Psychosocial Factors, Quality of Life, and Psychological Distress: Ethnic Differences in Patients with Heart Failure (2009)

Advances in treatment have prolonged life in heart failure (HF) patients, leading to increased attention to quality of life (QOL) and psychological functioning. It is not clear if ethnic differences exist in factors associated with psychological well-being. We examined psychosocial factors associated with depression and anxiety in 97 HF patients. Medical records were reviewed and patients (M age 53, 50% African American) completed surveys examining social support, coping, spirituality, and QOL for their association with depression and anxiety. Multiple regressions suggested that psychosocial factors were associated with psychological health. Patients with lower social support, lower meaning/peace and more negative coping reported greater depression; positive coping, and lower meaning/peace were associated with higher anxiety. Ethnicity stratified models suggested that spiritual well-being was associated with depression only among African Americans and QOL partially mediated this relationship. Findings suggest the importance of considering the unique psychosocial needs of diverse populations to appropriately target clinical interventions.
The Adsorption of Argon, Krypton and Xenon on Activated Charcoal (1996)

Charcoal adsorption beds are commonly used to remove radioactive noble gases from contaminated gas streams. The design of such beds requires the adsorption coefficient for the noble gas. Here an extension of the Dubinin-Radushkevich theory of adsorption is developed to correlate the effects of temperature, pressure, concentration, and carrier gas on the adsorption coefficients of krypton, xenon, and argon on activated carbon. This model is validated with previously published adsorption measurements. It accurately predicts the equilibrium adsorption coefficient at any temperature and pressure if the potential energies of adsorption, the micropore volume, and the van der Waals constants of the gases are known.
Root Pruning Pin Oak Liners Affects Growth and Root Morphology (2001)

Two experiments tested the effects of root pruning on growth during first-season production of pin oak ( Quercus palustris Muenchh.). Experiment one tested the effect of root pruning developing radicles at 5, 10, or 15 cm (2, 4, or 6 inches) below the substrate surface. After 11 weeks, total root length was not affected by root pruning, but root-pruned seedlings had more main lateral [>2-mm (0.08-inch) diameter] roots than those that were not root pruned. Shallow pruning increased the number of main lateral roots. Experiment two tested the effect of initially producing plants in different-depth bottomless containers [5, 10, 15, or 20-cm (2, 4, 6, or 8-inch) depth] on growth after transplanting to #2 [6 L (1.6 gal)] containers. Shoot and root growth in #2 containers were lowest when plants were originally produced in 5-cm-deep containers. Plants with the greatest height and highest root:shoot ratios were obtained when plants were grown initially in 10-cm-deep containers. Predicted optimum depth of bottomless containers from regression equations ranged from 11.3 cm (4.5 inches) to 14.2 cm (5.5 inches) for the different growth parameters measured. The importance of these findings are: Pruning developing radicles of pin oak seedlings increases the number of main lateral roots but not overall root length. Growers can maximize growth in #2 containers by initially growing in 10-cm-deep bottomless containers before transplanting to #2 containers.
3D Full waveform inversion on a Gulf of Mexico WAZ data set (2010)

In the last few years there has been an emphasis on using Full waveform inversion (FWI) in the real data environment. While the geological settings have been different, the common scheme was to use data sets that have relatively large cross‐line offsets and frequencies as low as 2.5 Hz. These measurements are the result of Wide azimuth (WAZ) towed streamer or Ocean Bottom Cable acquisition. These data acquisition methods offer better illumination, noise attenuation and lower frequencies to more accurately determine a velocity field for imaging. The methodology in this paper follows the layer striping approach where we developed the supra salt sediment followed by the top of salt, salt flanks, base of salt and finished with a limited subsalt update. The inversion stages were carefully QC‐ed through gather displays to ensure that the kinematics were honored. To approximate the observed data, the acoustic inversion had attenuation, anisotropy, acquisition source and receiver depth incorporated in the propagator. The final results were validated by reverse time migration using the inverted velocity field versus the final tomography velocity regime.