gebhart/patrepeval huggingface dataset:
Evaluating and improving performance of multimedia applications on simultaneous multi-threading (2003)

This paper presents the study and results of running several core multimedia applications on a simultaneous multithreading (SMT) architecture, including some detailed analysis ranging from memory-bounded kernels to computational-bounded functions. A performance metric to evaluate effective SMT performance gain is introduced, and compared to similar metrics on symmetric multiprocessor (SMP) systems. In addition, we analyze and compare SMT versus SMP systems, and highlight the advantages in the studied applications. The results indicate that sharing the cache in SMT processors can provide better cache locality and thus better performance although sharing the cache can introduce cache conflicts and reduce the actual cache size available for each logical processor. We also propose "mutual prefetching" -a technique to schedule threads so that they prefetch data for each other in order to reduce cache miss penalty.
The home visit. (1999)

With the advent of effective home health programs, an increasing proportion of medical care is being delivered in patients' homes. Since the time before World War II, direct physician involvement in home health care has been minimal. However, patient preferences and key changes in the health care system are now creating an increased need for physician-conducted home visits. To conduct home visits effectively, physicians must acquire fundamental and well-defined attitudes, knowledge and skills in addition to an inexpensive set of portable equipment. "INHOMESSS" (standing for: immobility, nutrition, housing, others, medication, examination, safety, spirituality, services) is an easily remembered mnemonic that provides a framework for the evaluation of a patient's functional status and home environment. Expanded use of the telephone and telemedicine technology may allow busy physicians to conduct time-efficient "virtual" house calls that complement and sometimes replace in-person visits.
Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles (2012)

Natural killer (NK) cells become activated during viral infection in response to cytokines or to engagement of NK cell activating receptors. However, the identity of cells sensing viral particles and mediating NK cell activation has not been defined. Here, we show that local administration of a modified vaccinia virus Ankara vaccine in mice results in the accumulation of NK cells in the subcapsular area of the draining lymph node and their activation, a process that is strictly dependent on type I IFN signaling. NK cells located in the subcapsular area exhibited reduced motility and were found associated with CD169(+)-positive subcapsular sinus (SCS) macrophages and collagen fibers. Moreover, depletion of SCS macrophages using clodronate liposomes abolished NK cell accumulation and activation. Our results identify SCS macrophages as primary mediators of NK cell activation in response to lymph-borne viral particles suggesting that they act as early sensors of local infection or delivery of viral-based vaccines.
Methylenolactocin, a novel antitumor antibiotic from Penicillium sp. (1988)

A novel antitumor antibiotic, methylenolactocin, was isolated from the culture filtrate of a new isolate of fungus identified as Penicillium sp. The fermentation yield reached about 100 mg per liter of the broth. Methylenolactocin has the molecular formula of C11H16O4 and possess an exomethylene lactone structure. Its structure was determined to be 3-carboxy-2-methylene-4-nonanolide by spectroscopic data. It is active against some Gram-positive bacteria and it prolongs the life span of mice inoculated with Ehrlich carcinoma.
Multi-domain Public key infrastructure for Vehicle-to-Grid network (2015)

Smart grid is a modern electrical grid that utilizes Information and Communication Technologies (ICT) and information networks. Growing attraction in Electric Vehicles (EV) shall likely provide a fundamental shift not only in transportation sector but also in the existing electrical grid infrastructure. In Vehicle-to-Grid (V2G) network, participating EVs can be used to store energy and supply this energy back to the power grid when required. To realize proper deployment of V2G network, charging infrastructure having various entities such as charging facility, clearinghouse, and energy provider has to be constructed. So use of Public key infrastructure (PKI) is indispensable for provisioning security solutions in V2G networks. The ISO/IEC 15118 standard is ascribed that incorporates X.509 PKI solution for V2G network. However, as traditional X.509 based PKI for V2G network has several shortcomings, we have proposed a multi-domain PKI model for V2G network that is built on elliptic curve cryptography and a self-certified public key technique having implicit certificate. We illustrate that the proposed solutions outperform the existing ones.
Vapor Reaction Growth of SnO<sub>2</sub> Single Crystals and Their Properties (1965)

In order to obtain single crystals of SnO 2 which can be used for the investigation of the intrinsic electrical and other related properties, crystal growth by the method using the vapor reaction of SnCl 4 with H 2 O was attempted, and was successfully performed. Colorless transparent single crystals with sizes up to 2×5×15 mm could be obtained by 24 hr run at 1300°C. The measurements of crystallographic properties, optical transmission, electrical conductivity and Hall effect were carried out with the grown single crystals. The crystals were found to be twins having {011} twinning plane. It was shown that the crystal is a typical n-type broad-band semiconductor having the value of the conductivity of a few Ω -1 ·cm -1 and the mobility of about 200 cm 2 ·volt -1 ·sec -1 at room temperature. The mobility of the crystals was found to change by the equation µ∝ T -2 above 250°K.
Synthesis of Some Classes of Multivariable Cascaded Transmission-Line Networks (1968)

Since the concept of multivariable positive real functions was introduced, the synthesis of these functions and matrices, concerning passive networks composed of lumped elements and of lumped and transmission-line elements, has been one of the most interesting problems in the field of circuit theory. This paper considers the synthesis of cascaded transmission-line networks of noncommensurate unit elements with the following structures: 1) a cascade connection of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</tex> transmission lines <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N_{i} (i= 1, 2, \cdots ,m)</tex> in a prescribed order, each <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N_{i}</tex> being a transmission line with open-ended stubs, composed of unit elements of a single variable <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p_{i}</tex> ; 2) a transmission line with open-ended stubs composed of unit elements of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">P_{2}</tex> , connected in cascade between two transmission lines composed of unit elements of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p_{1}</tex> ; 3) a cascade connection of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</tex> transmission lines <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N_{i} (i = 1, 2, \cdots ,m)</tex> in an arbitrary order, each <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N_{i}</tex> being a transmission line composed of unit elements of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">p_{i}</tex> ; and 4) a transmission line composed of commensurate unit elements with open-ended stubs, partitioned from a multivariable network.
Diaphragm interference pattern EMG and compound muscle action potentials: effects of chest wall configuration (1997)

The effect of chest wall configuration on the diaphragm electromyogram (EMGdi) was evaluated in five healthy subjects with an esophageal electrode for both interference pattern EMGdi (voluntary contractions) and electrically evoked diaphragm compound muscle action potentials (CMAPs). Diaphragm CMAPs (both unilateral and bilateral) were evaluated for the baseline-to-peak amplitude (Ampl), the time from the onset of the CMAP to first peak (T1), root mean square (RMS), and center frequency (CF) values of the CMAP power spectrum. CF values from the interference pattern EMGdi power spectrum were also calculated. For CMAPs obtained at an electrode position least influenced by variations induced by electrode positioning, Ampl increased with diaphragm shortening from functional residual capacity (FRC) to total lung capacity (TLC) by 101 and 98% (unilateral and bilateral, respectively). Bilateral CMAP RMS values increased 116% from FRC to TLC. CMAP T1 values decreased with diaphragm shortening from FRC to TLC by 1.1 and 2.1 ms for the unilateral and bilateral stimulations, respectively, and CF increased for the bilateral diaphragm CMAPs with diaphragm shortening. CF values from the interference pattern EMGdi did not show any consistent change with chest wall configuration. Thus CF values of the interference pattern EMGdi obtained with an esophageal electrode can be considered reliable for physiological interpretation, at any diaphragm length (if electrode positioning and signal contamination are controlled for), contrary to the diaphragm CMAPs, which are sensitive to changes in chest wall configuration. It is speculated that the different results (over the effects of chest wall configuration on interference pattern EMGdi and diaphragm CMAPs) amy be because of summation properties of the signals and how these influence the EMG power spectrum.
The Medial Axis of a Union of Balls. (2000)

We present an algorithm for computing the exact interior medial axis of a union of balls in IR d . Our algorithm combines the simple characterization of this medial axis given by Attali and Montanvert with the combinatorial information provided by Edelsbrunner&apos;s -shape. This leads to a very simple algorithm, which we implement in IR 3 . 1 Introduction There is considerable interest, in mesh generation, computer graphics, computer vision and medical imaging, in describing the shape of an object by its medial axis. But computing the medial axis of a three-dimensional object is dicult in general; it can be done for simple polyhedra using exact arithmetic and computational algebra [4]. Attali and Montanvert [1] showed that, in contrast, the medial axis of a three-dimensional union of balls has a simple structure. A union of balls, as the name suggests, is the union U of a set of balls B = fB 1 ; B 2 : : : Bn g in IR d . This is an important special case, since any three-dimension...
Numerical methods for the design of large-scale nonlinear discrete ill-posed inverse problems (2009)

Design of experiments for discrete ill-posed problems is a relatively new area of research. While there has been some limited work concerning the linear case, little has been done to study design criteria and numerical methods for ill-posed nonlinear problems. We present an algorithmic framework for nonlinear experimental design with an efficient numerical implementation. The data are modeled as indirect, noisy observations of the model collected via a set of plausible experiments. An inversion estimate based on these data is obtained by a weighted Tikhonov regularization whose weights control the contribution of the different experiments to the data misfit term. These weights are selected by minimization of an empirical estimate of the Bayes risk that is penalized to promote sparsity. This formulation entails a bilevel optimization problem that is solved using a simple descent method. We demonstrate the viability of our design with a problem in electromagnetic imaging based on direct current resistivity and magnetotelluric data.
Adenovirus EIIA early promoter: transcriptional control elements and induction by the viral pre-early EIA gene, which appears to be sequence independent. (1985)

A molecular dissection of the adenovirus EIIA early (E) promoter was undertaken to study the sequence elements required for transcription and to examine the nucleotide sequences, if any, specific for its trans-activation by the viral pre-early EIA gene product. A chimeric gene in which the EIIA-E promoter region fused to the coding sequences of the bacterial chloramphenicol acetyltransferase (CAT) gene was used in transient assays to identify the transcriptional control regions. Deletion mapping studies revealed that the upstream DNA sequences up to -86 were sufficient for the optimal basal level transcription in HeLa cells and also for the EIA-induced transcription. A series of linker-scanning (LS) mutants were constructed to precisely identify the nucleotide sequences that control transcription. Analysis of these LS mutants allowed us to identify two regions of the promoter that are critical for the EIIA-E transcription. These regions are located between -29 and -21 (region I) and between -82 and -66 (region II). Mutations in region I affected initiation and appeared functionally similar to the "TATA" sequence of the commonly studied promoters. To examine whether or not the EIIA-E promoter contained DNA sequences specific for the trans-activation by the EIA, the LS mutants were analyzed in a cotransfection assay containing a plasmid carrying the EIA gene. CAT activity of all of the LS mutants was induced by the EIA gene in this assay, suggesting that the induction of transcription of the EIIA-E promoter by the EIA gene is not sequence-specific.
Growth-Retarding Effect of Corn in Nicotinic Acid-Low Rations and Its Counteraction by Tryptophane (1945)

Either 50 mg 1(-)tryptophane or 1.0 mg nicotinic acid per 100 gms of ration completely counteracts the growth retardation caused by the inclusion of 40 per cent. corn grits in a low protein ration. A possible explanation of this observation is discussed.
Application of Artificial Intelligence Techniques in Drilling System Design and Operations: A State of the Art Review and Future Research Pathways (2016)

Abstract Artificial Intelligence (AI) has found extensive usage in simplifying complex decision-making procedures in practically every competitive market field, and oil and gas upstream industry is no exception to it. AI involves the use of sophisticated networking tools and algorithms in solving multifaceted problems in a way that imitates human intellect, with the aim of enabling computers and machines to execute tasks that could earlier be carried out only through demanding human brainstorming. Unlike other simpler computational automations, AI enables the designed tools to "learn" through repeated operation, thereby continuously refining the computing capabilities as more data is fed into the system. Over the years, AI has led to significant designing and computation optimizations in the global Petroleum Exploration and Production (E&P) industry, and its applications have only continued to grow with the advent of modern drilling and production technologies. Tools such as Artificial Neural Networks (ANN), Generic Algorithms, Support Vector Machines and Fuzzy Logic have a historic connection with the E & P industry for more than 16 years now, with the first application dated in 1989 for development of an intelligent reservoir simulator interface, and for well-log interpretation and drill bit diagnosis through neural networks. Devices and softwares with basis from the above mentioned AI tools have been proposed to abridge the technology gaps hindering automated execution and monitoring of key reservoir simulation, drilling and completion procedures including seismic pattern recognition, reservoir characterisation and history matching, permeability and porosity prediction, PVT analysis, drill bits diagnosis, overtime well pressure-drop estimation, well production optimization, well performance projection, well / field portfolio management and quick, logical decision making in critical and expensive drilling operations. The paper reviews and analyzes this successful integration of AI techniques as the missing piece of the puzzle in many reservoir, drilling and production aspects. It provides an update on the level of AI involvement in service operations and the application trends in the industry. A summary of various research papers and reports associated with AI usage in the upstream industry as well as its limitations has been presented.
Frontal Sinus Surgery: Endoscopic Technique and Preliminary Results (2000)

Endoscopic frontal sinus surgery, once the last frontier in the evolution of endoscopic sinus surgery, is considered difficult, risky to the patient, and likely to result in a high failure rate. We clarify the surgical anatomy for frontal sinus surgery that, based on a review of our data, provides safe and predictable access to the frontal sinus. We studied 200 consecutive patients with respect to indications, endoscopic and radiographic findings, results, and complications. The study will describe the technique in detail, including the following points: 1) computed tomography identification of the superior attachment of the uncinate process; 2) complete removal of the uncinate process, including its superior attachments, by using the microdebrider; 3) removal of the agger nasi cell, if present; and 4) verification of an open frontal sinus by a transillumination or image-guided system. Postoperative assessment of patients' symptoms and the confirmation of a patent frontal sinus by office endoscopy and transillumination indicated a 90% patency for short-term follow-up (average 12.2 months). There were no major complications. Postoperative complications included frontal recess stenosis, polypoid mucosa occluding the frontal recess, and middle turbinate lateralization. All of these situations may lead to recurrence of infection and symptoms. In-depth understanding of anatomic variations of the uncinate process and precise surgical removal of its superior attachments provide surgical access to the frontal sinus that is based on the natural ostia and is, therefore, more likely to remain patent.
Gastrointestinal effects and acute toxicity of suprofen. (1975)

The acute effects of orally administered, high doses of alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid (suprofen) were studied in various tests, related to gastrointestinal functions. A decrease of the diarrheal stools in the castor oil test in rats was the first effect noted; the ED50 in this test was 40 mg/kg. This dose is 540 times higher than the ED50 of suprofen in the acetic acid-induced writhing test in rats (ED50 = 0.074 mg/kg). Temporarily decreased food consumption in rats was first noted after administration of 80 mg/kg. This is more than 1000 times the ED50 in the rat anti-writhing test. The appearance of gastrointestinal lesions was also studied in rats and a direct quantitative comparison was made with indometacin, acetyl-salicylic acid and ketoprofen. The dose of suprofen that produced lesions in 50% of the rats was 200 mg/kg, viz. 2700 times the ED50 in the rat anti-writhing test. Similarly obtained safety margins are 9.0 for indometacin, 78 for acetyl-salicylic acid and 102 for ketoprofen. The mortality after a single oral administration of suprofen was studied in mice, rats, guinea-pigs and dogs. LD50-values, based on mortality 7 days after administration, were 590 mg/kg, 353 mg/kg, 280 mg/kg and more than 160 mg/kg, respectively. Comparative LD50's in mice and rats were 14 and 19 mg/kg for indometacin, 280 and 70 mg/kg for ketoprofen. Therefore the safety margin in rats, with respect to the ED50 in the acetic acid-induced writhing test, is 4770 for suprofen, 156 for ketoprofen and 17.3 for indometacin. In guinea-pigs the safety margin of suprofen is 1470 with respect to the ED50 in UV-erythema and in dogs more than 250 with respect to the ED50 in urate-induced arthritis. From these data we may conclude that suprofen is comparatively safer than the reference compounds studied and that its effects on the gastrointestinal tract appear at doses far above those required for effectiveness in tests related to pain, fever and inflammation.
Alteration of Striatal Tetrahydrobiopterin in Iron-Induced Unilateral Model of Parkinson's Disease (2014)

It has been suggested that transition metal ions such as iron can produce an oxidative injuries to nigrostriatal dopaminergic neurons, like Parkinson's disease (PD) and subsequent compensative increase of tetrahydrobiopterin (BH4) during the disease progression induces the aggravation of dopaminergic neurodegeneration in striatum. It had been established that the direct administration of BH4 into neuron would induce the neuronal toxicity in vitro. To elucidate a role of BH4 in pathogenesis in the PD in vivo, we assessed the changes of dopamine (DA) and BH4 at striatum in unilateral intranigral iron infused PD rat model. The ipsistriatal DA and BH4 levels were significantly increased at 0.5 to 1 d and were continually depleting during 2 to 7 d after intranigral iron infusion. The turnover rate of BH4 was higher than that of DA in early phase. However, the expression level of GTP-cyclohydrolase I mRNA in striatum was steadily increased after iron administration. These results suggest that the accumulation of intranigral iron leads to generation of oxidative stress which damage to dopaminergic neurons and causes increased release of BH4 in the dopaminergic neuron. The degenerating dopaminergic neurons decrease the synthesis and release of both BH4 and DA in vivo that are relevance to the progression of PD. Based on these data, we propose that the increase of BH4 can deteriorate the disease progression in early phase of PD, and the inhibition of BH4 increase could be a strategy for PD treatment.
Anterior cruciate ligament repair – past, present and future (2018)

Several promising avenues of further research now exist in the form of mechanical and biological augmentation techniques. Further work is clearly needed but there is renewed interest and focus for primary ACL repair that may yet prove the new frontier in ligament repair.
Assembly of phage lambda in vitro. (1966)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Photo-splitting of water to dihydrogen and hydroxyl radicals catalysed by rhodium-deposited perfluorinated poly(p-phenylene) (1995)

T. Kitamura, K. Maruo, Y. Wada, K. Murakoshi, T. Akano and S. Yanagida, J. Chem. Soc., Chem. Commun., 1995, 2189 DOI: 10.1039/C39950002189
Balloon-assisted coiling through a single 6F guiding catheter. (2006)

The new version of the 6F Envoy guiding catheter, with its enlarged inner diameter of 0.070 inch, is capable of simultaneously accommodating both a 0.014-inch microcatheter and a balloon microcatheter for balloon-assisted coiling (BAC). We report our experience using this guiding catheter for access in BAC in 48 patients. The guiding catheter allowed for easy manipulations of 2 microcatheters, while providing sufficient quality of control angiograms during the procedure. In cases in which BAC is indicated, a larger guiding catheter (7F) or the commonly used bifemoral approach is no longer necessary, making the procedure technically simpler for the operator and less traumatic to the vessel wall.