gebhart/patrepeval huggingface dataset:
Hepatocyte growth factor and Met/HGF receptors in patients with gastric adenocarcinoma. (1998)

Overexpression and amplification of Met/HGF receptor has been detected in gastric cancer tissues and cell lines. In this study hepatocyte growth factor (HGF) and Met/HGF receptors were localized in 32 gastric cancer and adjacent normal gastric tissues by the avidin-biotin-peroxidase complex technique. HGF (87.5%) and Met/HGF receptors (68.8%) were demonstrated in gastric cancer tissues. A high positive rate of HGF (87.0%) and Met/ HGF receptors (82.6%) presented in intestinal type gastric cancer. HGF immunoreactivity in gastric cancer tissues was a significant and powerful prognostic indicator (relative risk 15.9; p=0.01). These data suggest that HGF and Met/HGF receptors are involved in the morphogenesis of intestinal type gastric cancer. HGF may have other mechanism that favor gastric cancer spread and independently affect survival.
Determination of Trace Atrazine Levels in Water by a Sensitive Magnetic Particle-Based Enzyme Immunoassay (1996)

Atrazine is a pre- and post-emergence selective herbicide specific for broad-leaved weeds and grasses. Although extensively applied in the United States, its use in Europe is limited and restricted. European drinking water regulations are strict: allowable atrazine contamination levels are 100 parts per trillion (ppt, ng/L). As a result of European regulations, increased method sensitivity is needed to detect atrazine-contaminated water supplies. A sensitive and rapid enzyme immunoassay using specific atrazine antiserum covalently coupled to a magnetic particle solid phase has been developed for the quantitation of atrazine in water at parts per trillion levels. The immunoassay provides accurate detection to as low as 15 ppt of atrazine directly from a 250 μL water sample. Recovery from water samples without sample pretreatment averaged 100% and compared favorably to samples with GC/MS results (r = 0.993). The immunoassay represents a valuable method to detect trace amounts of atrazine in ground, surface, and drinking waters. Keywords: Atrazine; immunoassay; ELISA; triazine; herbicide
Commercial Molecular Distillation (1947)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCommercial Molecular DistillationK. C. D. HickmanCite this: Ind. Eng. Chem. 1947, 39, 6, 686–694Publication Date (Print):June 1, 1947Publication History Published online1 May 2002Published inissue 1 June 1947https://doi.org/10.1021/ie50450a002RIGHTS & PERMISSIONSArticle Views192Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts
Utterance-Level Multimodal Sentiment Analysis (2013)

During real-life interactions, people are naturally gesturing and modulating their voice to emphasize specific points or to express their emotions. With the recent growth of social websites such as YouTube, Facebook, and Amazon, video reviews are emerging as a new source of multimodal and natural opinions that has been left almost untapped by automatic opinion analysis techniques. This paper presents a method for multimodal sentiment classification, which can identify the sentiment expressed in utterance-level visual datastreams. Using a new multimodal dataset consisting of sentiment annotated utterances extracted from video reviews, we show that multimodal sentiment analysis can be effectively performed, and that the joint use of visual, acoustic, and linguistic modalities can lead to error rate reductions of up to 10.5 % as compared to the best performing individual modality. 1
The Relationship Between Specific RET Proto-oncogene Mutations and Disease Phenotype in Multiple Endocrine Neoplasia Type 2 (1996)

<h3>Objective.</h3> —Multiple endocrine neoplasia type 2 (MEN 2) is an autosomal dominant disorder. The 3 recognized subtypes include MEN 2A, characterized by medullary thyroid carcinoma (MTC), pheochromocytoma (pheo), and hyperparathyroidism (HPT); MEN 2B, by MTC, pheo, and characteristic stigmata; and familial MTC (FMTC), by the presence of MTC only. The purpose of this study was to establish the relationship between specific mutations and the presence of certain disease features in MEN 2 which could help in clinical decision making. <h3>Design.</h3> —Correlative survey study of 477 MEN 2 families. <h3>Setting.</h3> —Eighteen tertiary referral centers worldwide. <h3>Patients.</h3> —A total of 477 independent MEN 2 families. <h3>Main Outcome Measures.</h3> —Association between the position and type of germline mutation in the RET proto-oncogene and the presence or absence of MTC, pheo, HPT, and/or other features in a family. <h3>Results.</h3> —There is a statistically significant association between the presence of any mutation at a specific position (codon 634) and the presence of pheo and HPT. The presence of a specific mutation, CGC at codon 634, has yet to be associated with FMTC. Conversely, mutations at codons 768 and 804 are thus far seen only with FMTC, while codon 918 mutation is MEN 2B-specific. Rare families with both MEN 2 and Hirschsprung disease were found to have MEN 2-specific codon mutations. Patients with Hirschsprung disease presenting with such mutations should be monitored for the possible development of MEN 2 tumors. <h3>Conclusions.</h3> —This consortium analysis suggests that genotype-phenotype correlations do exist and, if made reliably absolute, could prove useful in the future in clinical management with respect to screening, surveillance, and prophylaxis, as well as provide insight into the genetic effects of particular mutations.
Globoside and Forssman synthases in human lymphocytes exposed to Epstein-Barr virus and mitogens. (1985)

The activities of two glycolipid synthetases, globoside synthase or UDP-N-acetylgalactosamine-trihexosylceramide beta-N-acetylgalactosaminyltransferase (beta-GalNAc transferase; EC 2.4.1.79) and Forssman synthase or UDP-N-acetylgalactosamine-globoside-alpha-N-acetylgalactosaminyltransfer ase (alpha-GalNAc transferase; EC 2.4.1.88), were assayed in various human lymphoblastic cell lines. The activity of beta-GalNAc transferase was much higher than that of alpha-GalNAc transferase except in Molt 3 and Molt 4 lines, which were derived from T-cells. In cultivated human peripheral lymphocytes concanavalin A (Con A), lipopolysaccharide (LPS), and Epstein-Barr virus (EBV) stimulated the activities of alpha- and beta-GalNAc transferases in addition to having their known stimulative effect on thymidine incorporation. Characteristic differences between alpha- and beta-GalNAc transferases were noted in the responses to the above mitogens, but activities of both enzymes were greatly increased by exposure of the lymphocytes to EBV. Treatment of lymphocytes with either dactinomycin (actinomycin D) or cycloheximide 24 hours after the addition of Con A, LPS, or EBV decreased the activities of the transferases. This observation suggests that stimulation of alpha- and beta-GalNAc transferases requires transcriptional and translational processes.
Micelles and aggregates of fluorinated surfactants (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicelles and aggregates of fluorinated surfactantsWen Guo, Tommy A. Brown, and B. M. FungCite this: J. Phys. Chem. 1991, 95, 4, 1829–1836Publication Date (Print):February 1, 1991Publication History Published online1 May 2002Published inissue 1 February 1991https://pubs.acs.org/doi/10.1021/j100157a060https://doi.org/10.1021/j100157a060research-articleACS PublicationsRequest reuse permissionsArticle Views722Altmetric-Citations77LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Endothelin and Cyclosporine Nephrotoxicity (1992)

Although some humoral and neural factors have been implicated in the persistent vasoconstriction characterizing many forms of acute renal failure, the mechanisms for this abnormal vascular function have remained largely unresolved. Several factors previously postulated to have a role in acute renal failure have been shown to enhance endothelin (Et) production or gene expression. We studied the potential pathophysiologic role for Et in several models of acute renal failure, including postischemia, endotoxin, and cyclosporine (Cy) nephrotoxicity. We have found that, in vivo, Cy (and also endotoxin) elevates circulating Et. We further showed that antagonizing Et's action with Et antibody ameliorates renal vasoconstriction following renal ischemia, Cy, and endotoxin administration. Additionally, our studies showed that even after circulating levels of Et decrease (following Cy), there is upregulation in Et receptors in the kidneys. Overall, endothelin appears to feature prominently in the pathophysiologic processes occurring during several forms of acute renal failure.
Peroxidase-mediated oxidation of isoniazid (1985)

Oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase at the expense of H2O2 yielded reactive species which were able to reduce nitroblue tetrazolium and bleach p-nitrosodimethylaniline. Nicotinic acid hydrazide oxidation did not cause these effects. At slightly alkaline pH, oxidation of isonicotinic acid hydrazide by horseradish peroxidase proceeded at the expense of molecular O2, and the reaction was oxygen consuming. The addition of H2O2 abolished O2 consumption. Bovine liver catalase enhanced the rate of nitroblue tetrazolium reduction and decreased the maximal velocity of the reaction proportionately to catalase concentration. During oxidation of isonicotinic acid hydrazide by horseradish peroxidase-H2O2, splitting of the heme group of horseradish peroxidase took place as shown by the disappearance of the Soret and minor bands in the visible region of the spectrum.
Numerical dispersion analysis of energy conserved splitting FDTD method for Maxwell's equations (2016)

In this paper, we explore the accuracy limits of an energy conserved splitting finite difference time domain (EC-S-FDTD) method applied to the Maxwell equations which has recently been proposed to solve the Electromagnetic (EM) problem. The numerical dispersion properties of the EC-S-FDTD methods are investigated. The results of this analysis are useful for the application of the method, and for the understanding of the behavior of the error of the method.
<i>Yersinia enterocolitica</i>infections associated with improperly pasteurized milk products: southwest Pennsylvania, March–August, 2011 (2013)

In July 2011, a cluster of Yersinia enterocolitica infections was detected in southwestern Pennsylvania, USA. We investigated the outbreak's source and scope in order to prevent further transmission. Twenty-two persons were diagnosed with yersiniosis; 16 of whom reported consuming pasteurized dairy products from dairy A. Pasteurized milk and food samples were collected from this dairy. Y. enterocolitica was isolated from two products. Isolates from both food samples and available clinical isolates from nine dairy A consumers were indistinguishable by pulsed-field gel electrophoresis. Environmental and microbiological investigations were performed at dairy A and pasteurization deficiencies were noted. Because consumption of pasteurized milk is common and outbreaks have the potential to become large, public health interventions such as consumer advisories or closure of the dairy must be implemented quickly to prevent additional cases if epidemiological or laboratory evidence implicates pasteurized milk as the outbreak source.
Hindi-to-Urdu Machine Translation through Transliteration (2010)

We present a novel approach to integrate transliteration into Hindi-to-Urdu statistical machine translation. We propose two probabilistic models, based on conditional and joint probability formulations, that are novel solutions to the problem. Our models consider both transliteration and translation when translating a particular Hindi word given the context whereas in previous work transliteration is only used for translating OOV (out-of-vocabulary) words. We use transliteration as a tool for disambiguation of Hindi homonyms which can be both translated or transliterated or transliterated differently based on different contexts. We obtain final BLEU scores of 19.35 (conditional probability model) and 19.00 (joint probability model) as compared to 14.30 for a baseline phrase-based system and 16.25 for a system which transliterates OOV words in the baseline system. This indicates that transliteration is useful for more than only translating OOV words for language pairs like Hindi-Urdu. 1
La reciente jurisprudencia del Tribunal Supremo sobre la competencia para conocer del procedimiento de exequátur de resoluciones judiciales extranjeras de divorcio (2018)

espanolEn el presente articulo analizaremos la reciente jurisprudencia del Tribunal Supremo, al resolver conflictos negativos de competencia entre los Juzgados espanoles, al analizar el articulo 52 de la Ley 29/2015, de cooperacion juridica internacional en materia civil EnglishIn the present article we will analyze the recent jurisprudence of the Supreme Court, when resolving negative conflicts of territorial jurisdiction between the Spanish Courts, when examining the article 52 of Act 29/2015, of international legal cooperation in civil matters.
TCP NewReno: Slow-but-Steady or Impatient? (2006)

In this paper, we compare the throughputs of two different TCP NewReno variants, namely Slow-but-Steady and Impatient. We develop analytic throughput models of these variants as a function of round-trip time, loss event rate, and the burstiness of packet drops within a loss event. Our models build upon prior work on TCP Reno throughput modeling, but extend this work to provide an analytical characterization of the NewReno fast recovery algorithms. We validated our models using the ns-2 simulator. Our models accurately predict the steady-state NewReno throughput for a wide range of loss rates. Based on these models, we analytically determine the preferred operating regions for each TCP variant. Our results show that the Slow-but-Steady variant is comparable to or superior to the Impatient variant in all but the most extreme scenarios for network packet loss.
Correlated mutations in models of protein sequences: phylogenetic and structural effects (1999)

Covariation analysis of sets of aligned sequences for RNA molecules is relatively successful in elucidating RNA secondary structure, as well as some aspects of tertiary structure [Gutell et al. (1992)].Covariation analysis of sets of aligned sequences for protein molecules is successful in certain instances in elucidating certain structural and functional links [Korber et al. (1993)], but in general, pairs of sites displaying highly covarying mutations in protein sequences do not necessarily correspond to sites that are spatially close in the protein structure [Gobel et al. (1994), Clarke (1995), Shindyalov et al. (1994), Thomas et al. (1996), Taylor &;Hatrick (1994), Neher (1994)].In this paper we identify two reasons why naive use of covariation analysis for protein sequences fails to reliably indicate sequence positions that are spatially proximate.The first reason involves the bias introduced in calculation of covariation measures due to the fact that biological sequences are generally related by a non-trivial phylogenetic tree.We present a null-model approach to solve this problem.The second reason involves linked chains of covariation which can result in pairs of sites displaying significant covariation even though they are not spatially proximate.We present a maximum entropy solution to this classic problem of "causation versus correlation".The methodologies are validated in simulation.
Synthesis of Multiple Antireflection Films over a Prescribed Frequency Band (1961)

The synthesis (as opposed to analysis) of multilayer dielectric films as antireflection coatings over any specified frequency band has not been attempted before. The similarity with transmission lines, which can be synthesized as multisection quarter-wave transformers to minimize reflection over any prescribed frequency band, is utilized by applying recently developed synthesis procedures for quarter-wave transformers to the synthesis of multiple antireflection films. [ See O. S. Heavens , Optical Properties of Thin Solid Films ( Academic Press, Inc., New York, 1955); and P. J. Leurgans , J. Opt. Soc. Am.41, 714 ( 1951).] A brief review of network synthesis is given, leading up to the synthesis of quarter-wave transformers and multilayer films. Numerical tables are presented in this paper from which antireflection coatings of up to four layers can be designed by interpolation. The design procedure (synthesis) described herein leads to the best possible antireflection films, but demands precisely controlled materials with certain refractive indices. It is hoped that this paper will help to promote the development of such materials, and will encourage opticists to try experimentally for the optimum performances possible in theory.
4-Aminopiperidine-4-carboxylic Acid:  A Cyclic α,α-Disubstituted Amino Acid for Preparation of Water-Soluble Highly Helical Peptides (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXT4-Aminopiperidine-4-carboxylic Acid: A Cyclic α,α-Disubstituted Amino Acid for Preparation of Water-Soluble Highly Helical PeptidesChristopher L. Wysong, T. Scott Yokum, Guillermo A. Morales, Rebekah L. Gundry, Mark L. McLaughlin, and Robert P. HammerView Author Information Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803 Cite this: J. Org. Chem. 1996, 61, 22, 7650–7651Publication Date (Web):November 1, 1996Publication History Received19 August 1996Published online1 November 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jo961594khttps://doi.org/10.1021/jo961594krapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views1759Altmetric-Citations68LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Anions,High-performance liquid chromatography,Monomers,Peptides and proteins,Reaction products Get e-Alerts
Effects of alkyl substituents in the chromic acid oxidation of tetralins (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffects of alkyl substituents in the chromic acid oxidation of tetralinsJohn W. Burnham, William P. Duncan, Edmund J. Eisenbraun, Gary W. Keen, and Mynard C. HammingCite this: J. Org. Chem. 1974, 39, 10, 1416–1420Publication Date (Print):May 1, 1974Publication History Published online1 May 2002Published inissue 1 May 1974https://pubs.acs.org/doi/10.1021/jo00926a021https://doi.org/10.1021/jo00926a021research-articleACS PublicationsRequest reuse permissionsArticle Views610Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The illustrated dictionary of electronics (1991)

The Illustrated Dictionary of Electronics includes definitions, abbreviations, acronyms, illustrations, schematics, diagrams, and conversion tables. Now in its sixth edition, the text includes updated definitions and enhanced illustrations. No matter what the level of skill - student, hobbyist, engineer, or technician - this dictionary aims to cover the spectrum of informational needs. Turner and Gibilisco thoroughly reference the terminology of computers, robotics, lasers, TV, radio, IC technology, digital and analog electronics, audio and video, power supplies, and fibre optic communications. Terms are defined clearly and precisely, with as little technical jargon as possible, so even beginning experimenters should be able to understand them.
The Evolution of Breast Implants (2014)

Breast augmentation remains one of the most common aesthetic procedures performed in the United States. Silicone implants have undergone an evolution with the availability of both fourth- and fifth-generation devices from the 3 leading manufacturers in the United States. This article explores the evolution of breast implants with special emphasis on the advancement of the silicone implants. Clinicians should strive to provide ongoing data and sound science to continue to improve clinical outcomes in the future.
Azelaic acid (2001)

The crystal structure of heptane-1,7-di­carboxyl­ic acid (azelaic acid), C9H16O4, has been redetermined at 180 K. The molecular units have twofold symmetry and are linked via the ubiquitous syn–syn carboxyl­ic acid dimer to form infinite chains running approximately along the [\overline 401] vector.