gebhart/patrepeval huggingface dataset:
Cross-platform Multimedia Application Development (2017)

Qt framework is a cross-platform SDK and a technology strategy that lets you quickly and cost-effectively design, develop, deploy, and maintain software while delivering a seamless user experience across all devices. One of the main focuses of the Qt framework is the development of powerful multimedia applications in a simple way through Qt Modeling Language (QML). It allows to develop applications/libraries only once and compile the same source code to multiple platforms. Qt is widely used by several companies around the world, however is still unknown in Brazil. This short-course has the mission to explore the use of Qt/QML for the development of Cross-platform multimedia applications.
An Innovative All-Active Hybrid Actuation System (2015)

In the context of More Electric Aircraft this paper addresses the objective of implementing power by wire actuators within primary flight controls. While full electric actuation is out of the question for the next generation of aircraft, hybrid actuation is intended in the meantime. Accordingly herein the architecture and potential of an innovative all-active hybrid actuation system is presented. It comprises three different principles of actuation, which are servo-hydraulic, electromechanic and electro-hydrostatic. Requirements and impacts of such a configuration are pointed out. A model following feed-forward control concept is introduced in order to equalize the actuator’s specific response behavior and imprint a uniform trajectory. Appropriate control electronics, that are responsible for position control, force fight compensation and state monitoring are presented. Furthermore a simulation model, which represents the discussed rudder control system, is introduced and simulation results are given. Finally a physical test bench is described, that shall demonstrate, to what extend the potential indicated by the simulation model can be reproduced with real hardware.
Image Reconstruction from Bag-of-Visual-Words (2014)

The objective of this study is to reconstruct images from Bag-of-Visual-Words (BoVW), which is the de facto standard feature for image retrieval and recognition. BoVW is defined here as a histogram of quantized descriptors extracted densely on a regular grid at a single scale. Despite its wide use, no report describes reconstruction of the original image of a BoVW. This task is challenging for two reasons: 1) BoVW includes quantization errors when local descriptors are assigned to visual words. 2) BoVW lacks spatial information of local descriptors when we count the occurrence of visual words. To tackle this difficult task, we use a large-scale image database to estimate the spatial arrangement of local descriptors. Then this task creates a jigsaw puzzle problem with adjacency and global location costs of visual words. Solving this optimization problem is also challenging because it is known as an NP-Hard problem. We propose a heuristic but efficient method to optimize it. To underscore the effectiveness of our method, we apply it to BoVWs extracted from about 100 different categories and demonstrate that it can reconstruct the original images, although the image features lack spatial information and include quantization errors.
Thrombolytic Treatment with Tissue-type Plasminogen Activator (t-PA) Containing Liposomes in Rabbits: a Comparison with Free t-PA (1995)

In this study, we aimed at improving the therapeutic index of tissue-type Plasminogen Activator (t-PA) as thrombolytic agent in the treatment of myocardial infarction. Liposome-encapsulated t-PA was tested in a rabbit jugular vein thrombosis model: administration of free t-PA (t-PA) as a bolus injection in the ear vein was compared to a similar administration of liposomal t-PA (t-PA-lip), liposomal t-PA in plasminogen-coated liposomes (Plg-t-PA-lip), a mixture of free t-PA and empty liposomes (t-PA+ empty lip) and a saline-blank (blank) in terms of thrombolytic activity and side effects. Liposomal t-PA (t-PA-lip/Plg-t-PA-lip) showed a significantly better thrombolysis efficiency than equimolar doses of free t-PA (t-PA/ t-PA+ empty lip): about 0.24 mg/kg of liposomal t-PA practically equalled the lysis-activity of a dose of free t-PA of 1.0 mg/kg (t-PA1mg/kg). On the other hand, liposome encapsulation did not affect the systemic activation of alpha 2-antiplasmin and plasminogen by t-PA. We conclude that for this model an improvement in thrombolytic efficacy of t-PA is achieved by liposome encapsulation of t-PA. As t-PA-lip and Plg-t-PA-lip -treatment induced similar results, targeting of liposomal t-PA by coupled glu-Plg remains a topic to be optimized in future studies.
Phase transition of the largest eigenvalue for nonnull complex sample covariance matrices (2005)

We compute the limiting distributions of the largest eigenvalue of a complex Gaussian sample covariance matrix when both the number of samples and the number of variables in each sample become large. When all but finitely many, say r, eigenvalues of the covariance matrix are the same, the dependence of the limiting distribution of the largest eigenvalue of the sample covariance matrix on those distinguished r eigenvalues of the covariance matrix is completely characterized in terms of an infinite sequence of new distribution functions that generalize the Tracy–Widom distributions of the random matrix theory. Especially a phase transition phenomenon is observed. Our results also apply to a last passage percolation model and a queueing model.
Commercial Implementation of Ultrasonic Velocity Imaging Methods via Cooperative Agreement Between NASA Lewis Research Center and Sonix, Inc. (1996)

This article describes the commercial implementation of ultrasonic velocity imaging methods developed and refined at NASA Lewis Research Center on the Sonix c-scan inspection system. Two velocity imaging methods were implemented: thickness-based and non-thickness-based reflector plate methods. The article demonstrates capabilities of the commercial implementation and gives the detailed operating procedures required for Sonix customers to achieve optimum velocity imaging results. This commercial implementation of velocity imaging provides a 100x speed increase in scanning and processing over the lab-based methods developed at LeRC. The significance of this cooperative effort is that the aerospace and other materials development-intensive industries which use extensive ultrasonic inspection for process control and failure analysis will now have an alternative, highly accurate imaging method commercially available.
Yeast 2 µm plasmid copy number is elevated by a mutation in the nuclear gene <i>UBC4</i> (2001)

The copy number of the Saccharomyces cerevisiae endogenous 2 microm plasmid is under strict control to ensure efficient propagation to the daughter cell without significantly reducing the growth rate of the mother or the daughter cell. A recessive mutation has been identified that resulted in an elevated but stable 2 microm plasmid copy number, which could be complemented by a genomic DNA clone containing the UBC4 gene, encoding an E2 ubiquitin-conjugating enzyme. A ubc4::URA3 deletion resulted in the same elevated 2 microm plasmid copy number. An analysis of the endogenous 2 microm transcripts revealed that the steady-state abundance of REP1, REP2, FLP and RAF were all increased 4-5-fold in the mutant. Analysis of the mutant ubc4 allele identified a single base pair mutation within the UBC4 coding region, which would generate a glutamic acid to lysine amino acid substitution within a region of conserved tertiary structure located within the first alpha-helix of Ubc4p. These investigations represent the first molecular characterization of a mutation within a Saccharomyces cerevisiae nuclear gene shown to affect 2 microm steady-state plasmid copy number and implicate the ubiquitin-dependent proteolytic pathway in host control of 2 microm plasmid copy number.
The Wittig Reaction. I. Synthesis of β,γ-Unsaturated Acids (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Wittig Reaction. I. Synthesis of β,γ-Unsaturated AcidsHoward S. Corey, J. R. D. McCormick, and William E. SwensenCite this: J. Am. Chem. Soc. 1964, 86, 9, 1884–1885Publication Date (Print):May 5, 1964Publication History Published online1 May 2002Published inissue 5 May 1964https://pubs.acs.org/doi/10.1021/ja01063a069https://doi.org/10.1021/ja01063a069research-articleACS PublicationsRequest reuse permissionsArticle Views343Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Glucose Polymer Molecular Weight Does Not Affect Exogenous Carbohydrate Oxidation (2005)

Despite previous reports of faster gastric emptying and glycogen resynthesis suggesting enhanced glucose delivery, a markedly hypotonic HMW glucose polymer solution had no effect on exogenous and endogenous substrate oxidation rates during exercise, relative to a LMW glucose polymer solution. These data are consistent with there being no effect of carbohydrate structure or solution osmolality or viscosity on exogenous glucose oxidation and that ingested glucose polymers can only be oxidized on average up to 1.0 g.min during exercise.
Regulation of urokinase receptor expression by protein tyrosine phosphatases (2006)

Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play a major role in several physiological processes such as cell migration, proliferation, morphogenesis, and regulation of gene expression. Many of the biological activities of uPA depend on its association with uPAR. uPAR expression and its induction by uPA are regulated at the posttranscriptional level. Inhibition of protein tyrosine phosphatase-mediated dephosphorylation by sodium orthovanadate induces uPAR expression and, with uPA, additively induces cell surface uPAR expression. Sodium orthovanadate induces uPAR by increasing uPAR mRNA in a time- and concentration-dependent manner. Both sodium orthovanadate and uPA induce uPAR mRNA stability, indicating that dephosphorylation could contribute to uPA-induced posttranscriptional regulation of uPAR expression. Induction of the tyrosine phosphatase SHP2 in Beas2B and H157 cells inhibits basal cell surface uPAR expression and uPA-induced uPAR expression. Sodium orthovanadate also increases uPAR expression by decreasing the interaction of a uPAR mRNA coding region sequence with phosphoglycerate kinase (PGK) as well as by enhancing the interaction between a uPAR mRNA 3' untranslated sequence with heterogeneous nuclear ribonucleoprotein C (hnRNPC). On the contrary, overexpression of SHP2 in Beas2B cells increased interaction of PGK with the uPAR mRNA coding region and inhibited hnRNPC binding to the 3' untranslated sequence. These findings confirm a novel mechanism by which uPAR expression of lung airway epithelial cells is regulated at the level of mRNA stability by inhibition of protein tyrosine phosphatase-mediated dephosphorylation of uPAR mRNA binding proteins and demonstrate that the process involves SHP2.
Structure and genetic variability of envelope glycoproteins of two antigenic variants of caprine arthritis-encephalitis lentivirus (1991)

To define the structure of the caprine arthritis-encephalitis virus (CAEV) env gene and characterize genetic changes which occur during antigenic variation, we sequenced the env genes of CAEV-63 and CAEV-Co, two antigenic variants of CAEV defined by serum neutralization. The deduced primary translation product of the CAEV env gene consists of a 60- to 80-amino-acid signal peptide followed by an amino-terminal surface protein (SU) and a carboxy-terminal transmembrane protein (TM) separated by an Arg-Lys-Lys-Arg cleavage site. The signal peptide cleavage site was verified by amino-terminal amino acid sequencing of native CAEV-63 SU. In addition, immunoprecipitation of [35S]methionine-labeled CAEV-63 proteins by sera from goats immunized with recombinant vaccinia virus expressing the CAEV-63 env gene confirmed that antibodies induced by env-encoded recombinant proteins react specifically with native virion SU and TM. The env genes of CAEV-63 and CAEV-Co encode 28 conserved cysteines and 25 conserved potential N-linked glycosylation sites. Nucleotide sequence variability results in 62 amino acid changes and one deletion within the SU and 34 amino acid changes within the TM.
RECOGNITION OF ENGINEERING DRAWING ENTITIES: REVIEW OF APPROACHES (2007)

Recognition of engineering drawing entities is one of the most difficult stages in engineering drawing interpretation and many attempts to recognize various types of ED entities have been made. In this paper, we review algorithms for the recognition of ED entities, especially dimensions and crosshatching areas. For the recognition of dimensions, we analyze how dimension texts can be separated from graphics and how arrowheads of dimension lines are recognized. We also analyze the recent systems of ED interpretation. Finally, future tasks are discussed.
Glucose-Responsive Peptide Coacervates with High Encapsulation Efficiency for Controlled Release of Insulin (2018)

A new glucose-responsive insulin delivery system is fabricated using biomimetic peptide coacervates derived from the Humboldt squid (Dosidicus Gigas) beak. Both insulin and glucose oxidase are coencapsulated within coacervate microdroplets. The glucose oxidase quickly responds to increasing glucose levels to generate a local acidic environment, thereby rapidly triggering the dissociation of pH-sensitive coacervates to release the insulin cargo. The rate of insulin release is dependent on the glucose level, increases under hyperglycemic conditions, and decreases under normoglycemic conditions. This glucose responsiveness mimics pancreatic β-cell function by releasing insulin according to glucose levels.
Morphologic Reappraisal of Serrated Colorectal Polyps (2003)

The "hyperplastic polyp" is considered a benign lesion with no malignant potential, whereas "serrated adenoma" is a precursor of adenocarcinoma. The morphologic complexity of the serrated adenoma varies from being clearly adenomatous to being difficult to distinguish from hyperplastic polyp, which creates a need for more detailed morphologic analysis of all serrated polyps. We evaluated 24 morphologic variables in 289 serrated polyps from the colon and rectum. Cluster analysis and discriminant analysis were performed. A subset of polyps was immunostained for hMLH1 and hMSH2. Major differences were found between right-sided and left-sided polyps. A distinct group of serrated polyps with abnormal proliferation was identified throughout the colon and rectum. These polyps demonstrated decreased expression of hMHL1 and hMSH2 compared with polyps with normal proliferation. Left-sided serrated polyps with normal proliferation further clustered into three groups: vesicular cell-type, goblet cell-type, and mucin-poor-type. We recommend evaluation of the localization, size, and morphologic features when serrated polyps are included in colorectal carcinogenesis research. Polyps with abnormal proliferation are similar to the polyps in "hyperplastic polyposis" and, because of their decreased expression of hMLH1 and hMSH2, may be the subset of polyps associated with the development of colorectal carcinoma via the microsatellite instability pathway.
Combined application of <i>in vivo</i> UV‐crosslinking and <i>in vitro</i> label transfer in the examination of AU‐rich sequence binding protein ‐ RNA interactions. (1995)

A combination of in vivo UV light-induced crosslinking of nucleic acids to proteins and in vitro label transfer assay was applied to investigate specific interactions between AU-rich sequences (ARE) in the 3' UTR of lymphokine mRNAs and cytoplasmic AU-rich sequence element binding proteins (AUBP) in normal human lymphoblasts and MLA 144 gibbon lymphoid tumor cells. We demonstrate that a pool of cytoplasmic AUBP can be effectively crosslinked to RNA in vivo, suggesting a close association of these proteins with ARE sequences in the cytoplasm. We also show that the UV-crosslinked AUBP pool is markedly reduced in malignantly transformed MLA 144 cells compared with normal lymphoblasts, indicating weaker interaction between lymphokine ARE and AUBP in these tumor cells. Similar differences in AUBP-RNA associations were found between the membrane-bound polysomal subfractions of the two cell types where most of the AUBP activity was localized. We suggest that the decreased AUBP-mRNA association in MLA 144 cells might reflect a process concerned with disturbances of mRNA metabolism in the neoplastic phenotype.
Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response (1997)

Thymidine dinucleotide (pTpT) stimulates melanogenesis in mammalian pigment cells and intact skin, mimicking the effects of UV irradiation and UV-mimetic DNA damage. Here it is shown that, in addition to tanning, pTpT induces a second photoprotective response, enhanced repair of UV-induced DNA damage. This enhanced repair results in a 2-fold increase in expression of a UV-damaged chloramphenicol acetyltransferase expression vector transfected into pTpT-treated skin fibroblasts and keratinocytes, compared with diluent-treated cells. Direct measurement of thymine dimers and (6-4) photoproducts by immunoassay demonstrates faster repair of both of these UV-induced photoproducts in pTpT-treated fibroblasts. This enhanced repair capacity also improves cell survival and colony-forming ability after irradiation. These effects of pTpT are accomplished, at least in part, by the up-regulation of a set of genes involved in DNA repair (ERCC3 and GADD45) and cell cycle inhibition (SDI1). At least two of these genes (GADD45 and SDI1) are known to be transcriptionally regulated by the p53 tumor suppressor protein. Here we show that pTpT activates p53, leading to nuclear accumulation of this protein, and also increases the specific binding of this transcription factor to its DNA consensus sequence.
Use of Calcium Dipicolinate for Enumeration of Total Viable Endospore Populations Without Heat Activation (1964)

A method, based on germination with 50 mm CaCl(2) and 40 mm sodium dipicolinate (Na(2)DPA), was developed for the determination of total viable counts of bacterial spores requiring heat activation. Incorporation of these germinating agents into Tryptone Glucose Extract Agar permitted plate-count enumeration of essentially 100% of Bacillus subtilis strain 5230 spores without a heat treatment. Other spore suspensions were surveyed for their response to CaCl(2) and Na(2)DPA, and for the subsequent removal of the heat-activation requirement for enumeration of maximal populations.
Effect of Shaped-Hole on Film Cooling Effectiveness of Gas Turbine Blade (2012)

Film cooling is vital to gas turbine blades to protect them from high temperatures and hence high thermal stresses. Improvements have been made to the cooling hole shaping of to provide higher heat transfer effectiveness. The present study of the impact of the film cooling turbine to protect from high temperatures through the Parametric study of blowing ratio, stream wise angle and the nature of the surface (concave and convex) on the film cooling effectiveness . In case study, it was taken three stream wise angles of 30, 60 and 90 with three blowing ratios 0.45, 1 and 2, and the sides of the turbine blade concave and convex. Using computational fluid dynamics software FLUENT ® and choosing the standard k-� model. It was concluded that the maximum centerline effectiveness with blowing ratio occurs at stream wise angle 30 on concave, convex and flat plate surface, the optimum blowing ratio on convex shape for
An Automatic Hybrid Segmentation Approach for Aligned Face Portrait Images (2009)

With the introduction of electronic personal documents (e.g. passports) in recent years the analysis of suitable photographs has become an important field of research. Such photographs for machine readable travel documents have to fulfill a set of minimal quality requirements defined by the International Civil Aviation Organization (ICAO). As some of the specified requirements are related to certain image regions only, these regions must be located in advance. In this work we present an automatic segmentation method for aligned color face images. The method is based on a convex variational energy formulation which is solved using weighted total variation. We apply constraints in the form of prior knowledge about the spatial configuration of typical passport photographs in order to solve for a global energy minimum. Several experiments on face images from two different datasets are presented to evaluate the performance of our algorithm. The obtained results demonstrate that our method is fairly robust and significantly outperforms other methods targeted at the same problem, in particular an expert system and an AdaBoost classifier. 1
Impact of Switching Glitches in Class-G Power Amplifiers (2012)

Envelope elimination and restoration (EER) based transmitters have attracted attention recently for two reasons: 1) The desire for increased spectral efficiency has mandated modulation standards that have large peak-to-average ratios (PAR). The increase in spectral efficiency is traded off against a decrease in average power-added-efficiency (PAE) when a linear power amplifier is used; however, when EER is used, it is decoupled somewhat from spectral efficiency. 2) Through the use of fast on-chip signal processing, the natural advantage of scaled CMOS is exploited by enabling switching power amplifier classes (e.g., class-E). This letter examines limitations associated with voltage supply switching glitches in class-G power amplifiers.
Embedding containerized workflows inside data science notebooks enhances reproducibility (2018)

Abstract Data science notebooks, such as Jupyter, combine text documentation with dynamically editable and executable code and have become popular for sharing computational methods. We present nbdocker , an extension that integrates Docker software containers into Jupyter notebooks. nbdocker transforms notebooks into autonomous, self-contained, executable and reproducible modules that can document and disseminate complicated data science workflows containing code written in different languages and executables requiring different software environments.