gebhart/patrepeval huggingface dataset:
Localised strain sensing of dielectric elastomers in a stretchable soft-touch musical keyboard (2015)

We present a new sensing method that can measure the strain at different locations in a dielectric elastomer. The method uses multiple sensing frequencies to target different regions of the same dielectric elastomer to simultaneously detect position and pressure using only a single pair of connections. The dielectric elastomer is modelled as an RC transmission line and its internal voltage and current distribution used to determine localised capacitance changes resulting from contact and pressure. This sensing method greatly simplifies high degree of freedom systems and does not require any modifications to the dielectric elastomer or sensing hardware. It is demonstrated on a multi-touch musical keyboard made from a single low cost carbon-based dielectric elastomer with 4 distinct musical tones mapped along a length of 0.1m. Loudness was controlled by the amount of pressure applied to each of these 4 positions.
Distribution of polymer deposition in glow discharge polymerization in a capacitively coupled system (1981)

Abstract The manner by which polymers created by plasma uniformly deposit onto substrates was sought. By rotating the substrate placed midway between electrodes, completely uniform distribution of polymer deposition was accomplished, and the deviation of the polymer deposition in a radius direction of the rotating substrate was within experimental errors. Materials of the substrate on which the polymer deposited had no influence on uiniformity of polymer deposition, but the electrical circuit of power source, i.e., grounding an electrode, markedly disturbed the uniformity. Thickness of polymers deposited on the substrate was linearly proportional to reaction time. Surface energies of deposited polymers prepared from methane, ethylene, and acetylene by plasma were independent of reaction time and were rather higher than those for conventionally polymerized polyolefines.
Electrical and mechanical behaviors of polymers at cryogenic temperatures. (1964)

Cryogenic temperature effects on electrical and mechanical properties of polymeric materials
Study on the stability of CH<sub>3</sub>NH<sub>3</sub>PbI<sub>3</sub>films and the effect of post-modification by aluminum oxide in all-solid-state hybrid solar cells (2013)

Degradation of perovskite has been a big problem in all-solid-state perovskite solar cells, although many researchers mainly focus on the high efficiency of these solar cells. This paper studies the stability of CH3NH3PbI3 films and finds that CH3NH3PbI3 is sensitive to moisture. The degradation reaction is proposed according to UV-Vis spectra and XRD results. In order to improve the degradation of CH3NH3PbI3, we introduce aluminum oxide as a post-modification material into all-solid-state perovskite solar cells for the first time. UV-Vis spectra show that Al2O3 modification could maintain the absorption of CH3NH3PbI3 after degradation. XRD results reveal that Al2O3 could protect perovskite from degradation. Moreover, the device post-modified by Al2O3 has shown more brilliant stability than that without modification when exposed to moisture. EIS results and dark current illustrate that the modification increased interface resistance in the dark, indicating the restrained electron recombination process.
Antidiscrimination Ordinances in Northwest Indiana: An Event-History Analysis of Municipal Policies Since 1992 (2019)

In recent years, municipalities throughout Indiana have passed antidiscrimination ordinances that protect the rights of individuals who belong to racial, ethnic, or sexual minorities. Political scientists have proposed competing theories of policy-adoption processes that suggest a number of internal factors (such as socioeconomic characteristics, governmental capacity, or issue salience) or external factors (such as mandates/incentives from higher-level governments or influence from neighboring communities) as predictors of policy adoption; however, most existing studies focus on state-level processes, and those that focus on municipalities consider only large cities in different states. To more clearly distinguish between state-level effects and local effects, this study focuses on municipalities of all sizes within one particular region (Northwest Indiana) since 1992 and considers various theories of municipal policy processes in order to develop a model that explains the intraregional variation in whether municipalities adopted antidiscrimination ordinances and when they did so. An event-history analysis (Cox proportional hazards regression) finds the strongest empirical support for a model of antidiscrimination-policy adoption that uses municipality size and the extent of local mediareporting on biasmotivated incidents as predictors.
The Wanton Farm of Jamestown, R.I. (1985)

This article focuses on the story of the Wanton Family farm on Conanicut Island during the American Revolution. Joseph Wanton Jr. was born in Newport in 1730. A Harvard graduate, and veteran of the French and Indian War, Wanton made his fortune as an overseas trader. As a loyalist, Wanton sought to escape Newport, where tensions were rising, and bought his farm on Conanicut Island. However, much of his fortune would be loss as the war with England proceeded, and many officials investigated Wanton for his loyalty to the English.
Common Sensing and Analyses to Visualize a Production Process with Parallelly Utilized Resource - Job-Shop and Flow-Shop Cases (2018)

This paper presented a common system of the automated sensing and analysis for major 2 types of manufacturing format; the flow-shop type and the job-shop type. About sensing, electrical signal from production equipment and/or tools were the main target of a general-purpose sensing. In particular, applications of a data logger are introduced. About analysis, discussion in this paper was focused on the classification of status of production resource, detection of its change in time-series, and so on. Some quantitative analyses, such a clustering , are required to be combined. In addition, the key performance indicator (KPI) was also developed for better visualization. We present KPI of “throughput yield” for the flow-shop, and "Parallel utilization index (PUI)" for the job-shop. All those have been evaluated by some numerical experiments for small and middle-sized companies of the Ibaraki IoT-Robot study group.
Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease. (1996)

Spontaneous inflammatory bowel disease (IBD) resembling human ulcerative colitis develops in mice mutant for the T cell receptor alpha gene (TCR-alpha-/-). TCR-alpha-/- mice lack TCR-alpha/beta+ cells but contain TCR-gamma/delta+ cells and a small population of a unique CD4+, TCR-alpha-/beta+(low) cells. Since all the immunoglobulin (Ig) classes are present in these mice, help to B cells must be provided by cells other than TCR-alpha/beta+ cells. In the present study, we found serum levels of IgG1 and IgG2 to be markedly increased in TCR-alpha-/- mice with IBD as compared to TCR-alpha-/- mice without IBD or TCR-alpha+/- controls. An increase in IgG1-, IgG2a- and IgA- but not IgM-secreting mesenteric lymph node (MLN) B cells was detected in TCR-alpha-/- mutant mice. There was also a marked increase in MLN B cells secreting autoantibody (IgG) to tropomyosin, a cytoskeletal protein. Examination of the hyperplastic MLN showed a marked increase in the number of B, TCR-delta+, and CD4+ TCR-alpha-/beta+ cells, similar to the cell population observed at the site of colonic inflammation. Analysis of spontaneous cytokine production by MLN cells using an enzyme-linked immunospot assay, immunohistochemistry, and reverse transcription/polymerase chain reaction showed a decrease of interleukin 2 (IL-2) but a marked increase of IL-4 and interferon gamma (IFN-gamma) production in TCR-alpha-/- mice with IBD as compared to TCR-alpha-/- mice without IBD and TCR alpha+/- control mice. Both TCR-alpha-/beta+ and TCR-delta+ cells were found to be capable of producing IL-4; IFN-gamma was produced mostly by non-T cells, many of which were shown to be CD3- NK 1.1+ cells. We propose that the cytokine imbalance present in these mice results in expansion of B cells, production and switching of autoantibodies to IgG2 subclass, and development of IBD. It is possible that the unusual CD4+ TCR-alpha-/beta+ population and expanded TCR-gamma/delta+ population present in TCR-alpha-/- mice plays a central role in this abnormal immune response.
Coherent optical MIMO (Invited Paper) (2005)

In this paper we present a Coherent Optical Multiple-Input Multiple-Output (COMIMO) communication system and its ability to exploit the inherent information capacity of Multi-Mode Fiber (MMF). COMIMO technique is a promising approach to unlock the information capacity of MMF as it ensures the necessary diversity for practically any fiber length. When exceeding the bandwidth-length product of the link, MIMO adaptive equalization can be used to mitigate inter-symbol interference (ISI). Furthermore, COMIMO link provides additional security in the physical layer that complements encryption.
Comparison of in vitro shoot regeneration protocols from <i>Rubus</i> leaf expiants (1992)

Abstract Three recently published protocols for the in vitro adventitious shoot regeneration of Rubus leaf expiants were compared using ‘Canby’ red raspberry. A consensus approach was designed combining the best features of the various protocols, and tested for three Rubus genotypes. Cultivar differences had a significant effect on the number of expiants regenerating shoots, the number of shoots per regenerating expiant, and on tissue growth rate. The most responsive cultivar for shoot regeneration from in vitro leaf expiants was ‘Canby’ red raspberry. Using the consensus approach developed in this study, 54% of ‘Canby’ leaf expiants regenerated with an average of 4.1 shoots per regenerating explant.
Diferensiasi Spesies Sibling Anopheles farauti Laveran 1902 Vektor Malaria di Jayapura dengan Scrutiny Morphometry Vena Sayap = Sibling Species Differentiation of Anopheles farauti Laveran 1902, A Malaria (2004)

ABSTRACT\nJayapura, one of malaria endemic areas in Indonesia, is a source of potential malaria transmission for another area, so it really need effort to malaria control. In order to succeed in malaria control, the treatment and vector control measures must be done all together. The vector control measures will be succesful if the vector mosquito can be recognized better, because the mosquitoes have numerous cryptic species, or isomorphic species or sibling species.\nThe objective of this study will to find discontinuity morphologic in the venation of An.farauti's wings, a malaria vector from many different characteristic areas (coastal or non coastal) in Jayapura by scrutinize morphometric.\nThe results of this study indicated that the length of mean Aniarauti's vena and the ratio of An.farauti's vena from coastal area (Skouw Mabo and Skouw Sae) were significantly distinct from Asei Kecil (non-coastal) meaning that they were a different species or a sibling species.\nKeywords: malaria -vector control -An.farauti -scrutinize morphometric
Stability and Subcellular Localization of Cytadherence-Associated Protein P65 in <i>Mycoplasma pneumoniae</i> (2001)

The surface protein P65 is a constituent of the Mycoplasma pneumoniae cytoskeleton and is present at reduced levels in mutants lacking the cytadherence accessory protein HMW2. Pulse-chase studies demonstrated that P65 is subject to accelerated turnover in the absence of HMW2. P65 was also less abundant in noncytadhering mutants lacking HMW1 or P30 but was present at wild-type levels in mutants lacking proteins A, B, C, and P1. P65 exhibited a polar localization like that in wild-type M. pneumoniae in all mutants having normal levels of HMW1 and HMW2. Partial or complete loss of these proteins, however, correlated with severe reduction in the P65 level and the inability to localize P65 properly.
Immunoassays and nucleic acid detection with a biosensor based on surface plasmon resonance. (1990)

A technique based on surface plasmon resonance is described which can be used to detect changes of refractive index that occur when one partner of a molecular binding pair diffuses from solution to bind the other partner which is immobilised on a silver surface. Results for the molecular binding pairs; protein-antibody, hapten-antibody and DNA-DNA are described. Instrumentation necessary for implementation of the technique is detailed. Immunoassay of proteins and haptens is possible in less than one minute with a sensitivity of 10(-9) mol/l. Hybridisation of 10 fmoles of a 97 base target sequence on the 1 mm2 area of detection to an immobilised oligonucleotide probe can be detected in less than five minutes. Advantages of the technique include the ability to record the kinetics of binding reactions in "real time" and the lack of labels in this simple assay format. Methods of improving the sensitivity are discussed.
Efficacy of Topiramate as Adjunctive Therapy in Refractory Partial Seizures: United States Trial Experience (1997)

In companion double-blind, placebo-controlled, dose-ranging trials performed in the United States, topiramate (TPM) daily target dosages of 200-1,000 mg/day were evaluated as add-on therapy in adults with refractory partial seizures with or without becoming secondarily generalized. Net reductions in median monthly seizure frequency (active drug minus placebo) with the most efficacious dosages of TPM were 35% in the low-dose trial and 40% in the high-dose trial. Substantial reductions in secondarily generalized seizures were also observed with TPM. TPM appears to be an efficacious new antiepileptic drug in the management of partial epilepsy.
Characterization of a nicotinamide–adenine dinucleotide‐dependent cation channel in the CRI‐G1 rat insulinoma cell line (1997)

1. Cell-free excised membrane patches were used to examine the properties of a novel nicotinamide-adenine dinucleotide (beta-NAD+)-activated ion channel in the rat insulin-secreting cell line, CRI-G1. 2. In inside-out recordings, beta-NAD+ (0.05-1.0 mM) induced the appearance of a channel characterized by extremely slow kinetics, with mean open times in the range of seconds. The estimated EC50 for activation was 114 microM. Channel activity declined with time (run-down) following activation by beta-NAD+ in excised patches and this was not prevented by intracellular application of trypsin. 3. The single channel current-voltage relationship was linear with a conductance of 74 pS in symmetrical NaCl. The channel appears equally permeable to Na+, K+ and Cs+, exhibits an appreciable permeability to Ca2+, Mg2+ and Ba2+, but excludes anions. 4. The channel displays an unusual voltage sensitivity, with an abrupt increase in open-state probability at depolarized voltages. 5. Channel opening, in the presence of beta-NAD+, required both Ca2+ and Mg2+ to be present at the internal side of the membrane. Activation by Ca2+ required a concentration of at least 10 microM and was maximal at 0.1 mM. Ba2+ did not substitute for Ca2+ in inducing channel activity nor did it inhibit activation by Ca2+. Increasing the concentration of intracellular Mg2+ stabilized the open state of NAD(+)-activated channels. 6. The non-selective cation channel reported here differs in its gating and modulatory characteristics from non-selective cation channels described in other tissues. This channel may play a role in the pathophysiological responses of beta-cells to oxidative stress.
Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis (2018)

Loss-of-function mutations in progranulin, a lysosomal glycoprotein, cause neurodegenerative disease. Progranulin haploinsufficiency causes frontotemporal dementia (FTD) and complete progranulin deficiency causes <i>CLN11</i> neuronal ceroid lipofuscinosis (NCL). Progranulin replacement is a rational therapeutic strategy for these disorders, but there are critical unresolved mechanistic questions about a progranulin gene therapy approach, including its potential to reverse existing pathology. Here, we address these issues using an AAV vector (AAV-<i>Grn</i>) to deliver progranulin in <i>Grn</i><sup>-/-</sup> mice (both male and female), which model aspects of NCL and FTD pathology, developing lysosomal dysfunction, lipofuscinosis, and microgliosis. We first tested whether AAV-<i>Grn</i> could improve preexisting pathology. Even with treatment after onset of pathology, AAV-<i>Grn</i> reduced lipofuscinosis in several brain regions of <i>Grn</i><sup>-/-</sup> mice. AAV-<i>Grn</i> also reduced microgliosis in brain regions distant from the injection site. AAV-expressed progranulin was only detected in neurons, not in microglia, indicating that the microglial activation in progranulin deficiency can be improved by targeting neurons and thus may be driven at least in part by neuronal dysfunction. Even areas with sparse transduction and almost undetectable progranulin showed improvement, indicating that low-level replacement may be sufficiently effective. The beneficial effects of AAV-<i>Grn</i> did not require progranulin binding to sortilin. Finally, we tested whether AAV-<i>Grn</i> improved lysosomal function. AAV-derived progranulin was delivered to the lysosome, ameliorated the accumulation of LAMP-1 in <i>Grn</i><sup>-/-</sup> mice, and corrected abnormal cathepsin D activity. These data shed light on progranulin biology and support progranulin-boosting therapies for NCL and FTD due to <i>GRN</i> mutations.<b>SIGNIFICANCE STATEMENT</b> Heterozygous loss-of-function progranulin (<i>GRN</i>) mutations cause frontotemporal dementia (FTD) and homozygous mutations cause neuronal ceroid lipofuscinosis (NCL). Here, we address several mechanistic questions about the potential of progranulin gene therapy for these disorders. <i>GRN</i> mutation carriers with NCL or FTD exhibit lipofuscinosis and <i>Grn</i><sup>-/-</sup> mouse models develop a similar pathology. AAV-mediated progranulin delivery reduced lipofuscinosis in <i>Grn</i><sup>-/-</sup> mice even after the onset of pathology. AAV delivered progranulin only to neurons, not microglia, but improved microgliosis in several brain regions, indicating cross talk between neuronal and microglial pathology. Its beneficial effects were sortilin independent. AAV-derived progranulin was delivered to lysosomes and corrected lysosomal abnormalities. These data provide <i>in vivo</i> support for the efficacy of progranulin-boosting therapies for FTD and NCL.
Neuropharmacology of Obesity: My Receptors Made Me Eat It (1998)

Article AbstractBody weight is regulated by complex interrelationships between central and peripheral factors. Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions. Recent discoveries are lending important insights into how these central and peripheral components of weight control are mediated by receptors for several key neurotransmitters and hormones.
Defining Cloud Services Workflow: A Comparison between TOSCA and OpenStack Hot (2015)

Cloud computing is driving formidable change in the technology industry and transforming how to do business in Europe and around the world. Despite the obvious advantages of cloud computing there are a number of issues that require solutions for Cloud computing to develop further. In particular challenges include (but are not limited to) lack of support for heterogeneous Cloud providers, lack of meaningful cross-platform Cloud resource descriptions, lack of lifecycle management of Cloud applications. In this paper we propose an overview of two solutions for cloud services description and orchestration, TOSCA (Topology and Orchestration Specification for Cloud Applications) and HOT (Heat Orchestration Template), a comparison among these two solution and examples of how these two solutions correlate with cloud patterns.
<b>Characterization of the ABA‐deficient tomato mutant</b><i><b>notabilis</b></i><b>and its relationship with maize</b><i><b>Vp14</b></i> (1999)

The notabilis (not) mutant of tomato has a wilty phenotype due to a deficiency in the levels of the plant hormone abscisic acid (ABA). The mutant appears to have a defect in a key control step in ABA biosynthesis--the oxidative cleavage of a 9-cis xanthophyll precursor to form the C15 intermediate, xanthoxin. A maize mutant, viviparous 14 (vp14) was recently obtained by transposon mutagenesis. This maize genetic lesion also affects the oxidative cleavage step in ABA synthesis. Degenerate primers for PCR, based on the VP14 predicted amino acid sequence, have been used to provide probes for screening a wilt-related tomato cDNA library. A full-length cDNA clone was identified which is specific to the not gene locus. The ORFs of the tomato cDNA and maize Vp14 are very similar, apart from parts of their N-terminal sequences. The not mutation has been characterized at the DNA level. A specific A/T base pair deletion of the coding sequence has resulted in a frameshift mutation, indicating that not is a null mutant. This observation is discussed in connection with the relatively mild phenotype exhibited by not mutant homozygotes.
Combined equalization and cochannel interference cancellation for the downlink using tentative decisions (2003)

The capacity of TDMA digital cellular systems like IS-136, GSM and their evolution IS-136HS and EDGE is limited by the intersymbol interference (ISI) arising from multipath propagation and co-channel interference (CCI) due to frequency reuse. The focus of this work is to develop for the downlink, a low complexity signal enhancing receiver that will work with a single receive antenna. This paper proposes a technique to combat both ISI and CCI using tentative decisions obtained through a preliminary detector. These decisions are used in mitigating ISI and CCI to produce final decisions. It is shown that the receiver proposed offers significant gains at high interfering signal powers especially when the channel memory is low.
The supermode structure of phase-locked diode laser arrays with variable channel spacing (1987)

The supermode structure of index-guided, phase-locked arrays of diode lasers with nonuniform laser spacing is investigated theoretically. It is shown that in a variable spacing array, the super-mode field patterns can be significantly different from those of a uniform array. However, in a variable-spacing array with <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</tex> elements, supermodes ν and <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N + 1 - \nu(\nu = 1, 2, ..., N)</tex> have similar near-field intensity patterns and modal gains, as in the case of uniform arrays. As a result, the discrimination between the fundamental (0° phase shift) and the highest order (180° phase shift) supermodes is small and depends sensitively on the amount of gain in the interchannel regions, as for uniform arrays. This may explain the inefficient supermode discrimination and the wide beams exhibited by variable-spacing diode laser arrays, in contrast to the strong discrimination and the narrow beams obtained with chirped (variable channel width) arrays structures.