gebhart/patrepeval huggingface dataset:
Serum and Middle Ear Antibody Response in the Chinchilla during Otitis Media with Effusion Induced by Nonviable Nontypeable Haemophilus influenzae (1992)

Journal Article Serum and Middle Ear Antibody Response in the Chinchilla during Otitis Media with Effusion Induced by Nonviable Nontypeable Haemophilus influenzae Get access Thomas F. DeMaria, Thomas F. DeMaria Search for other works by this author on: Oxford Academic PubMed Google Scholar Tatsuji Yamaguchi, Tatsuji Yamaguchi Search for other works by this author on: Oxford Academic PubMed Google Scholar Lauren O. Bakaletz, Lauren O. Bakaletz Search for other works by this author on: Oxford Academic PubMed Google Scholar David J. Lim David J. Lim Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 165, Issue Supplement_1, June 1992, Pages S196–S197, https://doi.org/10.1093/infdis/165-Supplement_1-S196 Published: 01 June 1992
Immunohistochemical investigation of dermal capillaries in chronic venous insufficiency. (1991)

Skin biopsies from the area of the medial malleolus of 24 patients with chronic venous insufficiency, of 5 patients without signs or history of chronic venous insufficiency and of seven corpses without manifestation of chronic venous insufficiency, were sectioned and stained with hematoxylin and eosin and with Ki-67, a monoclonal antibody expressed in the nuclei of proliferating cells. Hematoxylin- and eosin-stained sections of all specimens were assessed blindly to determine the state of capillary increase in stasis dermatosis. Twenty-four patients were found to have different stages of stasis dermatosis. During the examination of the Ki-67 frozen sections, close attention was paid to the capillary bed of all sections for any Ki-67-positive nuclei in capillary cells. None of the three groups showed positive staining of nuclei in capillary cells. This finding proves that there is no capillary proliferation, but an elongation and distension of the capillaries.
Polymer biocomposites with renewable sources (2010)

Nowadays production of natural biodegradable polymer composites is an important research topic on the stage of renewable sources implementation instead of petrochemical sources. In this work, possibilities of processing biocomposites on the base on different types of biopolymers – polylactide (PLA), thermoplastic starch (TPS), polyhydroxybutyrate (PHB), cellulose acetate (CA) - filled with natural fibers such as wood, kenaf, horse hair and nettle are presented. Large variety of natural fibers and their developed surface which increases adhesion to matrix makes them an attractive filler material. The fibers serve as reinforcement by giving strength and stiffness to the structure while the polymer matrix holds the fibers in place so that suitable structural composites can be made. Main physic-mechanical properties of natural fibers and biopolymers are presented. Modulus of elasticity and tensile strength increased with rising content of natural fibers in composite. The results show that biocomposites based on starch or PHB filled with kenaf fibers has the best mechanical properties. Modulus of elasticity achieves 10-12 GPa and tensile strength 50 MPa. This property can be interesting for packaging especially for fresh food like fruits or vegetables and for technical products with short-time life cycles. In future prospects, biocomposites based on biopolymers with a long time of decomposition can be interesting alternative as a construction material in automotive sectors.
Physical Map of the DNA Genome of <i>Autographa californica</i> Nuclear Polyhedrosis Virus (1979)

A physical map of the 88 x 10(6) dalton, circular DNA genome of Autographa californica nuclear polyhedrosis virus was constructed. The complete order of BamHI and XmaI restriction enzyme sites was determined. The EcoRI and HindIII fragments were partially ordered, and their general locations, relative to the BamHI and XmaI maps, were determined. Alterations in the restriction endonuclease fragment patterns of natural genotypic variants of A. californica nuclear polyhedrosis virus, including Trichoplusia ni MEV nuclear polyhedrosis virus, were located on the physical map. Alterations were found throughout the A. californica nuclear polyhedrosis virus DNA genome.
A distributed operating system for a workstation environment (2003)

A distributed processing operating system for software development is presented; it uses the Sun Network File System (NFS) and the Apollo Network Computing System (NCS). This system allows the transparent remote execution of processes. Local and remote agents are constructed for each program which is to be run remotely. The agents then coordinate, using NCS, the remote execution of the process. NFS is used to provide remote file access. The selection of the target host processor is made with the assistance of the DYNABASE network administration utility.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
XLII.—The nitration of m-nitrotoluene (1922)

O. L. Brady, J. Chem. Soc., Trans., 1922, 121, 328 DOI: 10.1039/CT9222100328
Primary Skin Fibroblasts as a Model of Parkinson's Disease (2012)

Parkinson's disease is the second most frequent neurodegenerative disorder. While most cases occur sporadic mutations in a growing number of genes including Parkin (PARK2) and PINK1 (PARK6) have been associated with the disease. Different animal models and cell models like patient skin fibroblasts and recombinant cell lines can be used as model systems for Parkinson's disease. Skin fibroblasts present a system with defined mutations and the cumulative cellular damage of the patients. PINK1 and Parkin genes show relevant expression levels in human fibroblasts and since both genes participate in stress response pathways, we believe fibroblasts advantageous in order to assess, e.g. the effect of stressors. Furthermore, since a bioenergetic deficit underlies early stage Parkinson's disease, while atrophy underlies later stages, the use of primary cells seems preferable over the use of tumor cell lines. The new option to use fibroblast-derived induced pluripotent stem cells redifferentiated into dopaminergic neurons is an additional benefit. However, the use of fibroblast has also some drawbacks. We have investigated PARK6 fibroblasts and they mirror closely the respiratory alterations, the expression profiles, the mitochondrial dynamics pathology and the vulnerability to proteasomal stress that has been documented in other model systems. Fibroblasts from patients with PARK2, PARK6, idiopathic Parkinson's disease, Alzheimer's disease, and spinocerebellar ataxia type 2 demonstrated a distinct and unique mRNA expression pattern of key genes in neurodegeneration. Thus, primary skin fibroblasts are a useful Parkinson's disease model, able to serve as a complement to animal mutants, transformed cell lines and patient tissues.
Endocytosis of Apolipoprotein A-V by Members of the Low Density Lipoprotein Receptor and the Vps10p Domain Receptor Families (2008)

Apolipoprotein A-V (apoA-V) is present in low amounts in plasma and has been found to modulate triacylglycerol levels in humans and in animal models. ApoA-V displays affinity for members of the low density lipoprotein receptor (LDL-R) gene family, known as the classical lipoprotein receptors, including LRP1 and SorLA/LR11. In addition to LDL-A binding repeats, the mosaic receptor SorLA/LR11 also possesses a Vps10p domain. Here we show that apoA-V also binds to sortilin, a receptor from the Vsp10p domain gene family that lacks LDL-A repeats. Binding of apoA-V to sortilin was competed by neurotensin, a ligand that binds specifically to the Vps10p domain. To investigate the biological fate of receptor-bound apoA-V, binding experiments were conducted with cultured human embryonic kidney cells transfected with either SorLA/LR11 or sortilin. Compared with nontransfected cells, apoA-V binding to SorLA/LR11- and sortilin-expressing cells was markedly enhanced. Internalization experiments, live imaging studies, and fluorescence resonance energy transfer analyses demonstrated that labeled apoA-V was rapidly internalized, co-localized with receptors in early endosomes, and followed the receptors through endosomes to the trans-Golgi network. The observed decrease of fluorescence signal intensity as a function of time during live imaging experiments suggested ligand uncoupling in endosomes with subsequent delivery to lysosomes for degradation. This interpretation was supported by experiments with (125)I-labeled apoA-V, demonstrating clear differences in degradation between transfected and nontransfected cells. We conclude that apoA-V binds to receptors possessing LDL-A repeats and Vsp10p domains and that apoA-V is internalized into cells via these receptors. This could be a mechanism by which apoA-V modulates lipoprotein metabolism in vivo.
Control of blood temperature and thermal energy balance during hemodialysis (1992)

In hemodialysis, the supervision and control of body temperature and thermal energy balance in the extracorporeal circuit can help to avoid hypotensive episodes. A feedback control of these parameters, which is not performed in today's treatments, can be achieved by influencing dialysate temperature. A Blood Temperature Monitor (BTM) was built which measures arterial and venous blood temperatures and performs control on either body temperature or extracorporeal thermal energy balance automatically. The control algorithms and examples from clinical applications are presented.
Redefining engineering education: the reflective practice of product design engineering (2001)

The University of Glasgow and the School of Design at the Glasgow School of Art have joined forces to redefine the nature of an engineering curriculum and produce a degree program that is rich in both creative design culture and design engineering skills. Graduates of this program are able, creatively, to critically analyze, evaluate and solve a diverse range of design and engineering problems, including their own life-long learning. This innovative curriculum enables graduates to enter the workforce as true reflective practitioners. This paper examines what can be achieved as a result of breaking down traditional engineering education barriers.
Novel Asymmetric Synthesis of Atropisomeric 6-Aryl Pyrazinones via an Unusual Chirality Transfer Process (1998)

Cyclization of (S,S)-alpha-[(1-phenylethyl)amino]-alpha-(2-iodophenyl)acetonitrile with (COCl)(2) in toluene or chlorobenzene afforded the atropisomeric pyrazinone (aS,S) 6-(2-alpha-iodophenyl)-3,5-dichloro-1-(1-phenylethyl)-2(1H)-pyrazinone in 57% yield. With smaller ortho substituents (F, Cl, CH(3), CF(3), OCH(3)) on the aromatic ring, mixtures of atropisomers were obtained from the cyclization reaction. All of the individual atropisomers prepared were stable at room temperature. All but the o-fluoro-substituted atropisomers were stable at elevated temperatures. This paper describes a stereoselective synthesis of pyrazinones and suggests a mechanism for formation via an interesting transfer of chirality.
Studies on Digitalis Glycosides. XXXI. Stepwise Degradation of Polydigitoxosides of Cardenolides (1970)

Stepwise degradation of the polydigitoxosides of cardenolides was achieved by met-aperiodate oxidation, reduction and subsequent hydrolysis under the specified conditions in good yield.
The Risks in Relying on Stakeholder Engagement for the Achievement of Sustainability (2005)

This paper examines the vaunted potential of stakeholder engagement for achieving sustainability, in theory and in practice. It identifies considerable risks inherent in relying on stakeholder engagement for the achievement of sustainability including misguided assumptions around stakeholder priorities in respect of sustainability, and around business interests in always acting to resolve stakeholder concerns. Stakeholder engagement is argued to be a mechanism that in a normative sense may be able to assist business in rethinking its interests in favor of sustainability, but if oversold or implemented instrumentally merely to legitimate 'business as usual', it is shown to represent an ill-fated panacea.
Structural and Genetic Analyses of O Polysaccharide from <i>Actinobacillus actinomycetemcomitans</i> Serotype f (2001)

The oral bacterium Actinobacillus actinomycetemcomitans is implicated as a causative agent of localized juvenile periodontitis (LJP). A. actinomycetemcomitans is classified into five serotypes (a to e) corresponding to five structurally and antigenically distinct O polysaccharide (O-PS) components of their respective lipopolysaccharide molecules. Serotype b has been reported to be the dominant serotype isolated from LJP patients. We determined the lipopolysaccharide O-PS structure from A. actinomycetemcomitans CU1000, a strain isolated from a 13-year-old African-American female with LJP which had previously been classified as serotype b. The O-PS of strain CU1000 consisted of a trisaccharide repeating unit composed of L-rhamnose and 2-acetamido-2-deoxy-D-galactose (molar ratio, 2:1) with the structure -->2)-alpha-L-Rhap-(1-3)-2-O-(beta-D-GalpNAc)-alpha-L-Rhap-(1-->* O-PS from strain CU1000 was structurally and antigenically distinct from the O-PS molecules of the five known A. actinomycetemcomitans serotypes. Strain CU1000 was mutagenized with transposon IS903phikan, and three mutants that were deficient in O-PS synthesis were isolated. All three transposon insertions mapped to a single 1-kb region on the chromosome. The DNA sequence of a 13.1-kb region surrounding these transposon insertions contained a cluster of 14 open reading frames that was homologous to gene clusters responsible for the synthesis of A. actinomycetemcomitans serotype b, c, and e O-PS antigens. The CU1000 gene cluster contained two genes that were not present in serotype-specific O-PS antigen clusters of the other five known A. actinomycetemcomitans serotypes. These data indicate that strain CU1000 should be assigned to a new A. actinomycetemcomitans serotype, designated serotype f. A PCR assay using serotype-specific PCR primers showed that 3 out of 20 LJP patients surveyed (15%) harbored A. actinomycetemcomitans strains carrying the serotype f gene cluster. The finding of an A. actinomycetemcomitans serotype showing serological cross-reactivity with anti-serotype b-specific antiserum suggests that a reevaluation of strains previously classified as serotype b may be warranted.
Laser Cladding (2004)

Capitalizing on the rapid growth and reduced costs of laser systems, laser cladding is gaining momentum, and in some instances replacing conventional techniques of depositing thin films because it can accommodate a great variety of materials, achieve uniform thickness and precise widths of layers, and provide improved resistance to wear and corrosi
Automatically identifying the function and intent of posts in underground forums (2018)

The automatic classification of posts from hacking-related online forums is of potential value for the understanding of user behaviour in social networks relating to cybercrime. We designed annotation schema to label forum posts for three properties: post type, author intent, and addressee. The post type indicates whether the text is a question, a comment, and so on. The author's intent in writing the post could be positive, negative, moderating discussion, showing gratitude to another user, etc. The addressee of a post tends to be a general audience (e.g. other forum users) or individual users who have already contributed to a threaded discussion. We manually annotated a sample of posts and returned substantial agreement for post type and addressee, and fair agreement for author intent. We trained rule-based (logical) and machine learning (statistical) classification models to predict these labels automatically, and found that a hybrid logical-statistical model performs best for post type and author intent, whereas a purely statistical model is best for addressee. We discuss potential applications for this data, including the analysis of thread conversations in forum data and the identification of key actors within social networks.
Measurement of deflection-mode damping in an accelerating structure (1991)

We have directly measured the damping of wake-field deflection modes in a slow-wave accelerating structure consisting of a dielectric-lined waveguide with segmented conducting boundaries wrapped with rf absorbing material. Such damping of deflection modes is desired to prevent beam breakup instabilities. Attenuation e-folding times of 246 ps were recorded for deflection modes at the Advanced Accelerator Test Facility while the quality of the desired accelerating mode remained unaffected.
The<b>mimR</b>Package for Graphical Modelling in<i>R</i> (2004)

The mimR package for graphical modelling in R is introduced. We present some facilities of mimR, namely those relating specifying models, editing models, fitting models and doing model search. We also discuss the entities needed for flexible graphical modelling in terms of an ob ject structure. An example about a latent variable model is presented.
Lifestyle and Cardiovascular Disease in Japan (2011)

The aim was to give on overview of the profile of cardiovascular disease, vascular pathology and the relationships between lifestyle and cardiovascular disease in Japanese. Compared with the United States and Europe, the higher mortality from stroke and lower mortality from coronary heart disease constitute a unique cardiovascular profile for Japan. A selective review of population-based pathology, trend and prospective cohort studies was performed to clarify the characteristics of cardiovascular disease and vascular pathology, trends in the incidence and mortality of cardiovascular disease, and the relationships between lifestyle and cardiovascular disease among Japanese adults. Since the 1970s, mortality from coronary heart disease as well as stroke has declined substantially in Japan, probably due to a major decline in blood pressure levels and for men a more recent decline in smoking, in spite of an increase in body mass index and total cholesterol levels. However, the decline in mortality was smaller and plateaued in middle-aged men aged 30-49 in the metropolitan cities of Tokyo and Osaka. The incidence of coronary heart disease has increased among middle-aged men residing in the suburbs of Osaka. As for the associations between lifestyle and cardiovascular disease, higher sodium, lower calcium and lower animal protein content in the diet and for men higher alcohol consumption may account for the higher prevalence of hypertension and higher risk of stroke for Japanese than for western populations. On the other hand, lower saturated fat (meat) and higher n3 polyunsaturated fat (fish) in the Japanese diet may contribute to the lower prevalence of hypercholesterolemia and lower risk of coronary heart disease among Japanese. Japan is unique among developed countries in that coronary heart disease mortality has been low and has continued to decline, while stroke mortality has declined substantially. However, a recent trend for coronary heart disease incidence to increase among urban men is a cause for concern as a potential source of future problems for public health and clinical practice in Japan.
Palladium and Nickel Catalyzed Chain Walking Olefin Polymerization and Copolymerization (2015)

In this perspective, recent developments on palladium and nickel mediated chain walking olefin polymerization and copolymerization with polar functionalized comonomers are described. First, the chain walking polymerization mechanism is discussed followed by its implications in olefin polymerization and copolymerization. Then, recent advances in catalyst design are provided. Special attention is paid to the influence of ligand structures on the catalytic properties. Subsequently, the applications of these chain walking polymerization catalysts in the synthesis of functionalized hyperbranched polymers and copolymers are summarized. Finally, some recent developments and perspectives on very fast and very slow chain walking polymerization catalysts are discussed.
Frequency and Temperature Dependence of Dielectric Properties of Pure Poly Vinylidene Fluoride (PVDF) Thin Films (2010)

In this work we have evaluated the dielectric properties of Poly Vinylidene fluoride (PVDF) thin films of thickness (≈20 μm) as a function of temperature from 40–70° C and frequency varying from 500 Hz to 100 kHz respectively for Al‐Al and Cu‐Cu electrode configuration. The dielectric constant values increases with the increase in temperature. A broad peak is found at around (70±5)° C. The maximum value of dielectric constant and dielectric losses were attributed to the phase transition of the polymer. The variation in dielectric constant and loss tangent suggest the net effect of some internal field within the polymer along with the external A.C. field.
Biomass Extraction Methods (2013)

Biomass represents an extremely valuable potential to obtain new clean energy sources and natural structurally complex bioactive compounds. Renewable energy can be produced from any biological feedstock, that contains appreciable amounts of sugar or materials that can be converted into sugar (e.g. starch or cellulose). Lignocellulose’s biomass–dendromass and phytomass is natural based material consisting of complex of heterogenic macromolecules with cell structure (celluloses, hemicelluloses and lignin) as well as numerous organic and inorganic structures with low molecule weight (Sun, 2002).
A System for Video Surveillance and Monitoring (2000)

The Robotics Institute at Carnegie Mellon University (CMU) and the Sarnoff Corporation are developing a system for autonomous Video Surveillance and Monitoring. The technical objective is to use multiple, cooperative video sensors to provide continuous coverage of people and vehicles in cluttered environments. This paper presents an overview of the system and significant results achieved to date. 1 Introduction The DARPA Image Understanding (IU) program is funding basic research in the area of Video Surveillance and Monitoring (VSAM) to provide battlefield awareness. The thrust of CMU&apos;s VSAM research is to develop automated video understanding algorithms that allow a network of active video sensors to automatically monitor objects and events within a complex, urban environment. We have developed video understanding technology that can automatically detect and track multiple people and vehicles within cluttered scenes, and to monitor their activities over long periods of time. Human an...