gebhart/patrepeval huggingface dataset:
A conservative femoral replacement for total hip arthroplasty (2000)

Between 1985 and 1993, 146 patients (162 hips) had total hip replacement (THR) using a conservative uncemented femoral component. The mean age of the patients was 50.8 years and the mean follow-up was 6.2 years (2 to 13). One patient was lost to follow-up, one died within two years of surgery and one had a revision procedure after a fracture sustained in a road-traffic accident. For the remaining 159, Kaplan-Meier survival analysis was calculated for the incidence of revision because of mechanical loosening or osteolysis. Survival without mechanical loosening at both five and ten years was 98.2%. Survival without osteolysis was 99% at five and 91% at ten years. The Harris hip score improved from a mean of 66.3 before to 90.4 at follow-up. Of particular note is the lack of thigh pain in this group. Radiological analysis showed that 139 stems (88%) had no measurable subsidence, 8 (5%) had less than 2 mm and 12 (7%) had more than 2 mm. Two of the eight and one of the 12 were revised for mechanical loosening. Nine hips were revised for late loosening associated with osteolysis. No reaming of the femoral canal was associated with statistically significant less blood loss compared with a comparable control group of uncemented implants (p < 0.0001). Our study suggests that using a conservative femoral implant does not protect against wear debris but the reliable mechanical stability (98.2%) makes this an attractive design of implant particularly for young patients.
Seismic imaging with a parallel multiple instruction multiple data (MIMD) computer (1990)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1990Seismic imaging with a parallel multiple instruction multiple data (MIMD) computerAuthors: Sotiris KapotasSuhas PhadkeErnest R. KanasewichConstantine TsingasSotiris KapotasUniversity of Alberta‐Edmonton, Canada, Suhas PhadkeUniversity of Alberta‐Edmonton, Canada, Ernest R. KanasewichUniversity of Alberta‐Edmonton, Canada, and Constantine TsingasUniversity of Alberta‐Edmonton, Canadahttps://doi.org/10.1190/1.1890192 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1890192FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1990ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1990 Pages: 1779 publication data© 1990 Copyright © 1990 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 10 Feb 2005 CITATION INFORMATION Sotiris Kapotas, Suhas Phadke, Ernest R. Kanasewich, and Constantine Tsingas, (1990), "Seismic imaging with a parallel multiple instruction multiple data (MIMD) computer," SEG Technical Program Expanded Abstracts : 347-350. https://doi.org/10.1190/1.1890192 Plain-Language Summary PDF DownloadLoading ...
Multi-Speaker DOA Estimation Using Deep Convolutional Networks Trained With Noise Signals (2019)

Supervised learning-based methods for source localization, being data driven, can be adapted to different acoustic conditions via training and have been shown to be robust to adverse acoustic environments. In this paper, a convolutional neural network (CNN) based supervised learning method for estimating the direction of arrival (DOA) of multiple speakers is proposed. Multi-speaker DOA estimation is formulated as a multi-class multi-label classification problem, where the assignment of each DOA label to the input feature is treated as a separate binary classification problem. The phase component of the short-time Fourier transform (STFT) coefficients of the received microphone signals are directly fed into the CNN, and the features for DOA estimation are learnt during training. Utilizing the assumption of disjoint speaker activity in the STFT domain, a novel method is proposed to train the CNN with synthesized noise signals. Through experimental evaluation with both simulated and measured acoustic impulse responses, the ability of the proposed DOA estimation approach to adapt to unseen acoustic conditions and its robustness to unseen noise type is demonstrated. Through additional empirical investigation, it is also shown that with an array of M microphone our proposed framework yields the best localization performance with M-1 convolution layers. The ability of the proposed method to accurately localize speakers in a dynamic acoustic scenario with varying number of sources is also shown.
Using a high-dimensional graph of semantic space to model relationships among words (2014)

The GOLD model (Graph Of Language Distribution) is a network model constructed based on co-occurrence in a large corpus of natural language that may be used to explore what information may be present in a graph-structured model of language, and what information may be extracted through theoretically-driven algorithms as well as standard graph analysis methods. The present study will employ GOLD to examine two types of relationship between words: semantic similarity and associative relatedness. Semantic similarity refers to the degree of overlap in meaning between words, while associative relatedness refers to the degree to which two words occur in the same schematic context. It is expected that a graph structured model of language constructed based on co-occurrence should easily capture associative relatedness, because this type of relationship is thought to be present directly in lexical co-occurrence. However, it is hypothesized that semantic similarity may be extracted from the intersection of the set of first-order connections, because two words that are semantically similar may occupy similar thematic or syntactic roles across contexts and thus would co-occur lexically with the same set of nodes. Two versions the GOLD model that differed in terms of the co-occurence window, bigGOLD at the paragraph level and smallGOLD at the adjacent word level, were directly compared to the performance of a well-established distributional model, Latent Semantic Analysis (LSA). The superior performance of the GOLD models (big and small) suggest that a single acquisition and storage mechanism, namely co-occurrence, can account for associative and conceptual relationships between words and is more psychologically plausible than models using singular value decomposition (SVD).
The Texas Instruments TMS320C25 Digital Signal Microcomputer (1986)

Capable of 10 million operations per second, the newest member of the TMS320 family can serve as an inexpensive alternative to bit-slice processors or custom ICs in digital signal processing applications.
A quantitative analysis of head movement behaviour during visual acuity assessment under prosthetic vision simulation (2007)

In most current vision prosthesis designs, head movement is the sole director of visual gaze and scanning due to the head-mounted nature of the camera. Study of this unnatural behaviour may provide insight into improved prosthesis designs and rehabilitation procedures. In this paper, we conducted a psychophysical study to investigate the characteristics of head movements of normally sighted subjects undergoing a visual acuity task in simulated prosthetic vision (SPV). In 12 naïve, untrained subjects, we recorded spontaneous changes in the amount of head movements during SPV sessions compared to control (normal vision) sessions. The observed behaviour continued to be refined until five or six sessions of practice. Increased head movement velocity was shown to be correlated to improved visual acuity performance, up to 0.3 logMAR, an equivalent of detecting details at half the physical size compared to complete deprivation of head movements. We postulate that visual scanning can as much as double the spatial frequency information in prosthetic vision. Increased head movement velocity observed when subjects were attempting smaller test items and for low-pass filtering schemes with higher cut-off frequencies may be further evidence that higher frequency content may be available through visual scanning, unconsciously driving subjects to increase head movement velocity.
Distributed routing with labeled distances (1992)

The author presents, verifies, and analyzes a new routing algorithm called the labeled distance-vector routing algorithm (LDR), that is loop-free at every instant, eliminates the counting-to-infinity problem of the distributed Bellman-Ford (DBF) algorithm, operates with arbitrary link and node delays, and provides shortest paths a finite time after the occurrence of an arbitrary sequence of topological changes. In contrast to previous successful approaches to loop-free routing, LDR maintains DBF's row-independence property and does not require internodal coordination spanning multiple loops. The new algorithm is shown to be loop-free and to converge in a finite time after an arbitrary sequence of topological changes. Its performance is compared with the performance of other distributed routing algorithms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Novel Risk Assessment Methodology for SCADA Maritime Logistics Environments (2018)

In recent years maritime logistics infrastructures are the global links among societies and economies. This challenges adversaries to intrude on the cyber-dependent ICTs by performing high-level intelligent techniques. A potential cyber-attack on such infrastructures can cause tremendous damages starting from supply chain service disruption ending up with threatening the whole human welfare. Current risk management policies embed significant limitations in terms of capturing the specific security requirements of ICTs and control/monitoring devices, such as IoT platforms, satellites and time installations, which are primary functioning for the provision of Maritime Logistics and Supply Chain (MLoSC) services. This work presents a novel risk assessment methodology capable of addressing the security particularities and specificities of the complex nature of SCADA infrastructures and Cyber-Physical Systems (CPSs) of the Maritime Logistics Industry. The methodology identifies asset vulnerabilities and threats to estimate the cyber-risks and their cascading effects within the supply chain, introducing a set of subsequent security assessment services. The utilization of these services is demonstrated via a critical, real-life SCADA scenario indicating how they can facilitate supply chain operators in comprehending the threat landscape of their infrastructures and guide them how to adopt optimal mitigation strategies to counter or eliminate their cyber-risks.
Über die Einwirkung von Schwefelkohlenstoff und Ätzkali auf Ketone (1908)

je eine Carboxithylgruppo.
Surface thermodynamics of bacterial adhesion (1983)

The adhesion of five strains of bacteria, i.e., Staphylococcus aureus (strain 049), Staphylococcus epidermidis (strain 047), Escherichia coli (strains 055 and 2627), and Listeria monocytogenes, to various polymeric surfaces was studied. The design of the experimental protocol was dictated by thermodynamic considerations. From the thermodynamic model for the adhesion of small particles from a suspension onto a solid substratum, it follows that the extent of adhesion is determined by the surface properties of all three phases involved, i.e., the surface tensions of the adhering particles, of the substrate, and of the suspending liquid medium. In essence, adhesion is more extensive to hydrophilic substrata (i.e., substrata of relatively high surface tension) than to hydrophobic substrata, when the surface tension of the bacteria is larger than that of the suspending medium. When the surface tension of the suspending liquid is larger than that of the bacteria, the opposite pattern of behavior prevails. Suspensions of bacteria at a concentration of 10(8) microorganisms per ml were brought into contact with several polymeric surfaces (Teflon, polyethylene, polystyrene, and acetal and sulfonated polystyrene) for 30 min at 20 degrees C. After rinsing, the number of bacteria adhering per unit surface area was determined by image analysis. The surface tension of the suspending medium. Hanks balanced salt solution, was modified through the addition of various amounts of dimethyl sulfoxide. It was found that the number of bacteria adhering per unit surface area correlates well with the thermodynamic predictions and that these data may be used to determine the surface tension of the different bacterial species. The surface tensions of the bacteria obtained in this fashion are in excellent agreement with those obtained by other methods.
Two effective single-loop high-performance sigma-delta modulators based on 0.13&#x00B5;m CMOS (2010)

In this paper, two high-resolution medium-bandwidth single-loop 4 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> -order single-bit sigma-delta modulators using a feed-forward and a feedback topology respectively are implemented in 0.13μm CMOS technology. The oversampling ratio is 50 with 312.5kHz input bandwidth, 14.66-bit and 16.62-bit resolution have been reached. The two circuits each consume about 8-mW from a single 1.2V supply voltage. After simulation, under the same circuit conditions, feedback structure gives better performance than feed-forward one. The experiment result could be a useful reference for the topology choice.
1.22 Tbit/s WDM transmission over 7,221 km with 38 nm bandwidth expanded by distributed Raman amplifier and EDFA (2002)

By using a signal bandwidth expansion combined with a distributed Raman amplifier and an EDFA, we have achieved WDM transmission over 7,221 km at 1.22 Tbit/s in the L-band alone. The scheme seems to be more practical because it has relatively low loss gain equalization, the shorter wavelength OSNR improvement, and effective gain tilt compensation.
Novel Ambipolar Orthogonal Donor–Acceptor Host for Blue Organic Light Emitting Diodes (2013)

Ambipolar triplet hosts comprising 1,2,4-triazole and carbazole in ortho-positions have been developed. The blue PHOLED has a high current efficiency of 47.1 cd A(-1), power efficiency of 41.2 lm W(-1), and low efficiency roll-off. The high efficiency was attributed to the successful control of π-conjugation through orthogonal arrangement of the substituents so that a wide T1-S0 gap could be maintained.
The Addition Reaction of Dinitrogen Trioxide with Cinnamyl Acetate (1965)

Abstract This study of the reaction between dinitrogen trioxide and cinnamyl acetate has indicated that the 3-acetoxy-2-nitro-1-phenyl-1-propylnitrite (IIb) is formed, in addition to 3-acetoxy-1 - nitroso- 2 -nitro - 1 - phenylpropane (IIa), in yield depending on the experimental conditions. Those products have been transformed in good yields into 1, 3-dimethoxy-2-nitro-1-phenylpropane, from which dl-erythro-2-amino-1-(p-nitrophenyl)-l, 3-propanediol has been synthesized.
Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model. (2002)

The proteasome is a ubiquitous and essential intracellular enzyme that degrades many proteins regulating cell cycle, apoptosis, transcription, cell adhesion,angiogenesis, and antigen presentation. We have shown recently that the proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human myeloma cells in vitro. In this study, we examined the efficacy, toxicity, and in vivo mechanism of action of PS-341 using a human plasmacytoma xenograft mouse model. One hundred immunodeficient (beige-nude-xid) mice were used in two independent experiments. The mice were injected s.c. with 3 x 10(7) RPMI-8226 myeloma cells. When tumors became measurable (9.2 days; range, 6-13 days after tumor injection), mice were assigned to treatment groups receiving PS-341 0.05 mg/kg (n = 13), 0.1 mg/kg (n = 15), 0.5 mg/kg (n = 14), or 1.0 mg/kg (n = 14) twice weekly via tail vein, or to control groups (n = 13) receiving the vehicle only. Significant inhibition of tumor growth, even with some complete tumor regression, was observed in PS-341-treated mice. The median overall survival was also significantly prolonged compared with controls (30 and 34 days for high dose-treated mice versus 14 days for controls; P < 0.0001). PS-341 was well tolerated up to 0.5 mg/kg, but some mice treated at 1.0 mg/kg became moribund and lost weight. Analysis of tumors harvested from treated animals showed that PS-341 induced apoptosis and decreased angiogenesis in vivo. These studies therefore demonstrate that PS-341 has significant in vivo antimyeloma activity at doses that are well tolerated in a murine model, confirming our in vitro data and further supporting the early clinical promise of PS-341 to overcome drug resistance and improve patient outcome.
Trehalose Induces the ADP-Glucose Pyrophosphorylase Gene,<i>ApL3</i>, and Starch Synthesis in Arabidopsis (2000)

In Arabidopsis, genes encoding functional enzymes for the synthesis and degradation of trehalose have been detected recently. In this study we analyzed how trehalose affects the metabolism and development of Arabidopsis seedlings. Exogenously applied trehalose (25 mM) strongly reduced the elongation of the roots and, concomitantly, induced a strong accumulation of starch in the shoots, whereas the contents of soluble sugars were not increased. When Arabidopsis seedlings were grown on trehalose plus sucrose (Suc), root elongation was restored, but starch still accumulated to a much larger extent than during growth on Suc alone. The accumulation of starch in the shoots of trehalose-treated seedlings was accompanied by an increased activity of ADP-glucose pyrophosphorylase and an induction of the expression of the ADP-glucose pyrophosphorylase gene, ApL3. Even in the presence of 50 mM Suc, which itself also slightly induced ApL3, trehalose (5 mM) led to a further increase in ApL3 expression. These results suggest that trehalose interferes with carbon allocation to the sink tissues by inducing starch synthesis in the source tissues. Furthermore, trehalose induced the expression of the beta-amylase gene, AT-beta-Amy, in combination with Suc but not when trehalose was supplied alone, indicating that trehalose can modulate sugar-mediated gene expression.
WE‐G‐214‐06: Pulmonary Ventilation and Perfusion Imaging Using 4DCT (2011)

Purpose: To develop a functional imaging technique that can simultaneously detect changes in lung ventilation and lung perfusion using 4D‐CT. This high‐resolution functional information can be incorporated in a treatment planning to minimize the dose to highly functional areas of the lung, and can also be used to assess the efficacy of treatment post radiation therapy. Methods: Recently, a technique was presented to estimate lung ventilation using 4DCT by detecting the changes in CT characteristics of the pulmonary parenchyma. We go a step further and develop the theory to extract not only regional fractional changes in ventilation but also fractional changes in mass that may be indicative of blood flow. Changes in lung ventilation are estimated by applying a mass correction that is estimated using the ratio of the global inhale‐mass and end‐exhale mass. Changes in lung perfusion are indicated by changes in “apparent mass”. Changes in “apparent mass” are estimated by applying a volume correction that is estimated using the ratio of global inhale volume and end‐exhale volume. In both the cases a subtraction of the corrected images is performed by spatially matching the images at each phase of the respiratory cycle. Spatial matching is carried out using a deformable image registration algorithm. Results: Preliminary studies indicate a linear relationship between the mass‐corrected fractional changes in volume and global measurement of tidal volume changes (slope = 1.01, R‐square = 0.97). A similar slightly linear relationship is observed between the volume‐corrected fractional changes in “apparent mass” and global measurement of mass (slope = 1.21, R‐square = 0.75). Conclusions: The technique presented above can extract both changes in ventilation and “apparent mass” that maybe indicative of perfusion simultaneously from a single set of 4DCT images. It however remains to the shown that these changes correspond to perfusion (future studies).
12% lactate lotion for the treatment of xerosis. A double-blind clinical evaluation (1983)

• Sixty patients with moderate to severe xerosis participated in a 21-day, randomized, double-blind, contralateral study for efficacy of a specially neutralized 12% lactate lotion compared with a 5% lactic acid lotion and a nonlactated emollient lotion. The severity of xerosis was evaluated on days 0, 7, 14, and 21 during treatment and on days 28 and 35 one and two weeks after treatment was discontinued. All three preparations significantly reduced the severity scores of xerosis. During the "regression" period after treatment was discontinued, patients receiving 12% lactate lotion, compared with those treated with nonlactated emollient lotion, had had significantly greater reductions in the severity scores of xerosis for the lateral calf area at days 28 and 35 and for total severity scores (combined mean differences for lateral, medial, and pretibial areas) at day 35. Compared with 5% lactic acid lotion, the 12% lactate lotion provided significantly greater reductions for total severity scores at days 28 and 35. (<i>Arch Dermatol</i>1983;119:27-30)
Potassium promoter for palladium on alumina selective hydrogenation catalysts (1991)

Y. H. Park and G. L. Price, J. Chem. Soc., Chem. Commun., 1991, 1188 DOI: 10.1039/C39910001188
Estimating the National Public Health Burden Associated with Exposure to Ambient PM<sub>2.5</sub> and Ozone (2011)

Ground‐level ozone (O 3 ) and fine particulate matter (PM 2.5 ) are associated with increased risk of mortality. We quantify the burden of modeled 2005 concentrations of O 3 and PM 2.5 on health in the United States. We use the photochemical Community Multiscale Air Quality (CMAQ) model in conjunction with ambient monitored data to create fused surfaces of summer season average 8‐hour ozone and annual mean PM 2.5 levels at a 12 km grid resolution across the continental United States. Employing spatially resolved demographic and concentration data, we assess the spatial and age distribution of air‐pollution‐related mortality and morbidity. For both PM 2.5 and O 3 we also estimate: the percentage of total deaths due to each pollutant; the reduction in life years and life expectancy; and the deaths avoided according to hypothetical air quality improvements. Using PM 2.5 and O 3 mortality risk coefficients drawn from the long‐term American Cancer Society (ACS) cohort study and National Mortality and Morbidity Air Pollution Study (NMMAPS), respectively, we estimate 130,000 PM 2.5 ‐related deaths and 4,700 ozone‐related deaths to result from 2005 air quality levels. Among populations aged 65–99, we estimate nearly 1.1 million life years lost from PM 2.5 exposure and approximately 36,000 life years lost from ozone exposure. Among the 10 most populous counties, the percentage of deaths attributable to PM 2.5 and ozone ranges from 3.5% in San Jose to 10% in Los Angeles. These results show that despite significant improvements in air quality in recent decades, recent levels of PM 2.5 and ozone still pose a nontrivial risk to public health.