gebhart/patrepeval huggingface dataset:
Die copolymerisation des acroleins mit einigen vinylmonomeren. Polymere acroleine. 9. Mitt. (1958)

Abstract Die Copolymerisation des Acroleins in wäßrigem Medium wird untersucht und die copolymerisationsparameter folgender Systeme bestimmt: Acrolein/Aacrylnitril (r 1 = 1,09; r 2 = 0,77); Acrolein/Acrylamid (r 1 = 2,0; r 2 = 0,76); Acrolein/Acrylsäuremethylester (r 1 = 0,2; r 2 = 10,0) und Acrolein/Vinylacetat (r 1 = 3,3; r 2 = 0,1). Ferner werden die Qund e‐Werte für Acrolein berechet und sein Verhalten bei der Copolymerisation diskutiert.
A Critical Role for HSP90 in Cancer Cell Invasion Involves Interaction with the Extracellular Domain of HER-2 (2007)

HSP90 is a ubiquitously expressed molecular chaperone that controls the folding, assembly, intracellular disposition, and proteolytic turnover of many proteins, most of which are involved in signal transduction processes. Recently, a surface form of HSP90 has been identified and associated with cell migration events. In this paper, we explore the interaction of surface HSP90 with HER-2, a receptor-like glycoprotein and member of the ErbB family of receptor tyrosine kinases that play central roles in cellular proliferation, differentiation, and migration as well as in cancer progress. The involvement of HSP90 in the regulation of HER-2 has been attributed so far to receptor stabilization via interaction with its cytoplasmic kinase domain. Here we present evidence, using glutathione S-transferase pull-down and transfection assays, for a novel interaction between surface HSP90 and the extracellular domain of HER-2. Specific disruption of this interaction using mAb 4C5, a function-blocking monoclonal antibody against HSP90, inhibits cell invasion accompanied by altered actin dynamics in human breast cancer cells under ligand stimulation conditions with heregulin. Additionally, disruption of surface HSP90/HER-2 interaction leads to inhibition of heregulin-induced HER-2-HER-3 heterodimer formation, reduced HER-2 phosphorylation, and impaired downstream kinase signaling. Interestingly, this disruption does not affect HER-2 internalization. Our data suggest that surface HSP90 is involved in heregulin-induced HER-2 activation and signaling, leading to cytoskeletal rearrangement, essential for cell invasion.
Mechanisms of optical limiting in fullerene-doped π-conjugated organic structures demonstrated with polyimide and COANP molecules (2002)

Possible mechanisms of optical limiting of visible radiation in conjugated organic structures based on polyimides and substituted pyridines sensitized with C60 and/or C70 fullerenes are studied using the Z-scan method. It is shown that reverse saturable absorption, two-photon absorption, and complex formation between the donor fragment of a π-conjugated molecule and fullerene contribute to the processes of nonlinear absorption. The absorption cross sections for excited states of the charge transfer complexes based on polyimide 6B-C70 and 2-cyclooctylamino-5-nitropyridine-C70 systems are calculated. The data obtained are quantitatively interpreted and compared with those provided by alternative methods.
Bulk Bismuth as a High‐Capacity and Ultralong Cycle‐Life Anode for Sodium‐Ion Batteries by Coupling with Glyme‐Based Electrolytes (2017)

Sodium-ion batteries (SIBs) have attracted great interest for large-scale electric energy storage in recent years. However, anodes with long cycle life and large reversible capacities are still lacking and therefore limiting the development of SIBs. Here, a bulk Bi anode with surprisingly high Na storage performance in combination with glyme-based electrolytes is reported. This study shows that the bulk Bi electrode is gradually developed into a porous integrity during initial cycling, which is totally different from that in carbonate-based electrolytes and ensures facile Na<sup>+</sup> transport and structural stability. The achievable capacity of bulk Bi in the NaPF<sub>6</sub> -diglyme electrolyte is high up to 400 mAh g<sup>-1</sup> , and the capacity retention is 94.4% after 2000 cycles, corresponding to a capacity loss of 0.0028% per cycle. It exhibits two flat discharge/charge plateaus at 0.67/0.77 and 0.46/0.64 V, ascribed to the typical two-phase reactions of Bi ↔ NaBi and NaBi ↔ Na<sub>3</sub> Bi, respectively. The excellent performance is attributed to the unique porous integrity, stable solid electrolyte interface, and good electrode wettability of glymes. This interplay between electrolyte and electrode to boost Na storage performance will pave a new pathway for high-performance SIBs.
Geometry and bone density. (2006)

Bone development is a key process in the growing child. It is, therefore, of paramount importance to survey this process, which is characterized by increasing length and size of the bone together with its progressive mineralization. The bone status can be evaluated by different techniques, each of them having its pros and cons. Furthermore, it should be underlined that the results of bone assessment depend not only from the employed technique but also from the auxological characteristics of the subjects. It is, therefore, the aim of this review to examine the characteristics of the various methods of bone evaluation, such as dual energy X-ray absorptiometry (DEXA), peripheral quantitative computed tomography (pQCT), ultrasound and metacarpal index and to explain how changes in bone structure and geometry may influence the results.
Methods to Circumvent a Difficult Coupling in the Solid-Phase Synthesis of Cyclosporine Analogues (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTMethods to Circumvent a Difficult Coupling in the Solid-Phase Synthesis of Cyclosporine AnaloguesPrakash Raman, Suzanne S. Stokes, Yvonne M. Angell, George R. Flentke, and Daniel H. RichView Author Information Department of Chemistry and School of Pharmacy, University of Wisconsin, 425 North Charter Street, Madison, Wisconsin 53706-1515 Cite this: J. Org. Chem. 1998, 63, 17, 5734–5735Publication Date (Web):July 30, 1998Publication History Received12 May 1998Published online30 July 1998Published inissue 1 August 1998https://pubs.acs.org/doi/10.1021/jo980889qhttps://doi.org/10.1021/jo980889qrapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views544Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Monomers,Organic polymers,Organic reactions,Peptides and proteins,Precursors Get e-Alerts
Computer Design and Fabrication Techniques for a Wideband Dielectric Mirror (1969)

A computer program is used to aid in the design of a forty-seven layer wideband dielectric mirror. An integral part of the fabrication of the new design is a computerized prescription which provides a means of monitoring layer deposition. The theoretical mirror bandwidth is 6000 cm(-1) centered about 14400 cm(-1). Transmission varies between 0.6% and 2.6% with one point of 7.4% transmission at the 14400 cm(-1) center. The transmission over a wide bandwidth is obtained from the superposition and interleaving of the layers of three different wideband high reflecting mirrors. There is very good agreement between the calculated and experimental reflectance curves.
Interdomain B in ZAP-70 Regulates but Is Not Required for ZAP-70 Signaling Function in Lymphocytes (1999)

The protein tyrosine kinase ZAP-70 plays an important role in T-cell activation and development. After T-cell receptor stimulation, ZAP-70 associates with the receptor and is phosphorylated on many tyrosines, including Y292, Y315, and Y319 within interdomain B. Previously, we demonstrated that Y292 negatively regulates ZAP-70 function and that Y315 positively regulates ZAP-70 function by interacting with Vav. Recent studies have suggested that Y319 also positively regulate ZAP-70 function. Paradoxically, removal of interdomain B (to create the construct designated Delta), containing the Y292, Y315, and Y319 sites, did not eliminate the ability of ZAP-70 to induce multiple gene reporters in Syk-deficient DT-40 B cells and ZAP-70/Syk-deficient Jurkat cells. Here we show that Delta still utilizes the same pathways as wild-type ZAP-70 to mediate NF-AT induction. This is manifested by the ability of Delta to restore induction of calcium fluxes and mitogen-activated protein kinase activation and by the ability of dominant negative Ras and FK506 to block the induction of NF-AT activity mediated by Delta. Biochemically we show that the stimulated tyrosine phosphorylation of Vav, Shc, and ZAP-70 itself is diminished, whereas that of Slp-76 is increased in cells reconstituted with Delta. Deletion of interdomain B did not affect the ability of ZAP-70 to bind to the receptor. The in vitro kinase activity of ZAP-70 lacking interdomain B was markedly reduced, but the kinase activity was still required for the protein's in vivo activity. Based on these data, we concluded that interdomain B regulates but is not required for ZAP-70 signaling function leading to cellular responses.
Band-Structure Approach to Synthesis of Grating Couplers with Ultra-High Coupling Efficiency and Directivity (2015)

We propose a complex-wavevector band-structure approach to synthesis of fiber-to-chip grating couplers, and show apodized bi-level designs with 95% coupling efficiency and 99% directivity using only two device layers of a monolithic SOI CMOS process.
Transplantation of the LGR6+ Epithelial Stem Cell into Full-Thickness Cutaneous Wounds Results in Enhanced Healing, Nascent Hair Follicle Development, and Augmentation of Angiogenic Analytes (2014)

The LGR6+ epithelial stem cells appear to hold great promise for the development of a clinically useful stem cell–based therapy for the repair of full-thickness wounds and hair regeneration. These results indicate that transplantation of LGR6+ epithelial stem cells promotes epithelialization, hair growth, and angiogenesis in tissues destined for scar formation.
Atomic Layer Deposition of Ru Thin Films Using 2,4-(Dimethylpentadienyl)(ethylcyclopentadienyl)Ru by a Liquid Injection System (2007)

Ru thin films were grown on Si, , , and TiN substrates by atomic-layer deposition using 2,4-(dimethylpentadienyl)(ethylcyclopentadienyl)Ru and as Ru precursor and reactant, respectively, at temperatures ranging from . A saturated growth rate of and a low oxygen concentration (below the detection limit of Auger electron spectroscopy) were obtained at . The Ru film showed a negligible incubation period on all the different types of substrates, and an active nucleation behavior which resulted in a very smooth film surface morphology. The dimethylpentadienyl ligand enhanced the active nucleation of Ru and retarded the oxidation of the grown Ru layer. Good step coverage was obtained from the Ru film grown on a capacitor hole with an aspect ratio of 17 and an opening diameter of by a proper control of the Ar carrier gas flow rate.
The motor cortex of the rat: Cytoarchitecture and microstimulation mapping (1982)

The first motor (MI) cortex of the rat was identified as the region from which movements could be evoked by the lowest intensity of electrical stimulation. The location of this region was correlated with cytoarchitecture in the frontal and parietal cortex. Two frontal areas can be discerned in Nissl-stained sections: (1) the medial agranular field, marked by a pale-staining layer III and a compact layer II, and (2) the lateral agranular field, which has more homogeneous superficial layers and a broad layer V containing large, densely staining cells. Both of these regions project to the spinal cord and can therefore be included in the somatic sensorimotor cortex. MI in the rat coincides with the lateral agranular field but also overlaps with part of the adjacent granular cortex of the first somatic sensory (SI) representation. We conclude that the rat MI cortex can be identified by microstimulation techniques and by cytoarchitecture in the rat.
The Measurement of Grease Noise in Electric Motor Grade Ball Bearings (1976)

This paper discusses the design, development, and successful use of an electronic instrument for the evaluation of grease noise in electric motor grade ball bearings. No evidence was found that grease noises were harmful to the proper mechanical operation of the ball bearings. However, it did segregate ball bearings that would, in a motor, produce psychologically irritating noises due to grease that were unacceptable to appliance manufacturers. The evaluation suggests ways in which devices such as the ball bearing noise tester can be used to assist the manufacturers of ball bearings and lubricating greases in developing standards that soon may become necessary because of the new emphasis on the ecological significance of noise.
Retinal nerve fiber layer height in high-tension glaucoma and healthy eyes. (1998)

We found that the strongest correlations with the visual field were with the new polar and new inferior sector.
Programmable Bandpass Filter and Tone Generator Using Bucket-Brigade Delay Lines (1974)

Bucket-brigade devices have been used to build a new type of active filter that is equivalent to a second-order digital filter without the need for complex analog-to-digital conversion. The filter response characteristics, i.e., center frequency and bandwidth, depend on the circuit parameters of gain and clock frequency, both of which may be electronically controlled. By using a variable clock signal, 1023 frequencies can be accurately selected by the proper setting of ten switches. The selected clock frequency uniquely determines the center frequency of the bucket-brigade filter. The programmable feature of the clock circuit, therefore, allows the convenient selection of the center frequency of the bandpass filter. A slight modification to the programmable bandpass filter converts it into a programmable oscillator. Thus, any one of 1023 tones can be generated by the proper setting of the switches. A device that exhibits both filter and oscillator functions has been demonstrated in the laboratory.
The effect of ultra-thin Al<sub>2</sub>O<sub>3</sub>layers on the dielectric properties of LaAlO<sub>3</sub>thin film on silicon (2004)

High-k LaAlO3 (LAO) thin films with and without Al2O3 buffer layers were deposited on n-type silicon substrates using pulsed laser deposition method. The dielectric constant of the LAO thin film increased from 5.2 to 23.1 as its thickness increased from 20 to 500 A. The effective dielectric constants of the LAO (120 A)/Si and LAO(105 A)/Al2O3(15 A)/Si were 12.5 and 23.2, respectively. The flatband voltage of the LAO(105 A)/Al2O3(15 A)/Si sample decreased from 2.0 V to 1.2 V after the sample was annealed for 5 min at 850 °C in air atmosphere, while the dielectric constant value of the annealed sample did not change. It was found that a 15 A thick Al2O3 buffer layer could enhance the dielectric properties of the LAO thin film, making it one of the good candidates for high-k materials.
Preparation of metallocenes from hydrocarbon dianions (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of metallocenes from hydrocarbon dianionsThomas J. Katz, Nancy. Acton, and Geoffrey. MartinCite this: J. Am. Chem. Soc. 1973, 95, 9, 2934–2939Publication Date (Print):May 1, 1973Publication History Published online1 May 2002Published inissue 1 May 1973https://doi.org/10.1021/ja00790a034RIGHTS & PERMISSIONSArticle Views231Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (875 KB) Get e-Alerts Get e-Alerts
Two systolic architectures for modular multiplication (2000)

The authors present two systolic architectures to speed up the computation of modular multiplication in RSA cryptosystems. In the double-layer architecture, the main operation of Montgomery's algorithm is partitioned into two parallel operations after using the precomputation of the quotient bit. In the non-interlaced architecture, we eliminate the one-clock-cycle gap between iterations by pairing off the double-layer architecture. We compare our architectures with some previously proposed Montgomery-based systolic architectures, on the basis of both modular multiplication and modular exponentiation. The comparisons indicate that our architectures offer the highest speed, lower hardware complexity, and lower power consumption.
From genes to public health: the applications of genetic technology in disease prevention. Genetics Working Group. (1996)

Although most current genetic tests are not ready for disease prevention, there is an important role for the public health community in translating genetic technology into disease prevention.
Multi-Biomarkers for Early Detection of Type 2 Diabetes, Including 10- and 12-(Z,E)-Hydroxyoctadecadienoic Acids, Insulin, Leptin, and Adiponectin (2015)

We have previously found that fasting plasma levels of totally assessed 10- and 12-(Z,E)-hydroxyoctadecadienoic acid (HODE) correlated well with levels of glycated hemoglobin (HbA1c) and glucose during oral glucose tolerance tests (OGTT); these levels were determined via liquid chromatography-mass spectrometry after reduction and saponification. However, 10- and 12-(Z,E)-HODE alone cannot perfectly detect early impaired glucose tolerance (IGT) and/or insulin resistance, which ultimately lead to diabetes. In this study, we randomly recruited healthy volunteers (n = 57) who had no known history of any diseases, and who were evaluated using the OGTT, the HODE biomarkers, and several additional proposed biomarkers, including retinol binding protein 4 (RBP4), adiponectin, leptin, insulin, glycoalbumin, and high sensitivity-C-reactive protein. The OGTT revealed that our volunteers included normal individuals (n = 44; Group N), "high-normal" individuals (fasting plasma glucose 100-109 mg/dL) with IGT (n = 11; Group HN+IGT), and diabetic individuals (n = 2; Group D). We then used these groups to evaluate the potential biomarkers for the early detection of type 2 diabetes. Plasma levels of RBP4 and glycoalbumin were higher in Group HN+IGT, compared to those in Group N, and fasting levels of 10- and 12-(Z,E)-HODE/linoleic acids were significantly correlated with levels of RBP4 (p = 0.003, r = 0.380) and glycoalbumin (p = 0.006, r = 0.316). Furthermore, we developed a stepwise multiple linear regression models to predict the individuals' insulin resistance index (the Matsuda Index 3). Fasting plasma levels of 10- and 12-(Z,E)-HODE/linoleic acids, glucose, insulin, and leptin/adiponectin were selected as the explanatory variables for the models. The risks of type 2 diabetes, early IGT, and insulin resistance were perfectly predicted by comparing fasting glucose levels to the estimated Matsuda Index 3 (fasting levels of 10- and 12-(Z,E)-HODE/linoleic acids, insulin, and leptin/adiponectin).
Challenges of DNA profiling in mass disaster investigations. (2005)

In cases of mass disaster, there is often a need for managing, analyzing, and comparing large numbers of biological samples and DNA profiles. This requires the use of laboratory information management systems for large-scale sample logging and tracking, coupled with bioinformatic tools for DNA database searching according to different matching algorithms, and for the evaluation of the significance of each match by likelihood ratio calculations. There are many different interrelated factors and circumstances involved in each specific mass disaster scenario that may challenge the final DNA identification goal, such as: the number of victims, the mechanisms of body destruction, the extent of body fragmentation, the rate of DNA degradation, the body accessibility for sample collection, or the type of DNA reference samples availability. In this paper, we examine the different steps of the DNA identification analysis (DNA sampling, DNA analysis and technology, DNA database searching, and concordance and kinship analysis) reviewing the "lessons learned" and the scientific progress made in some mass disaster cases described in the scientific literature. We will put special emphasis on the valuable scientific feedback that genetic forensic community has received from the collaborative efforts of several public and private USA forensic laboratories in assisting with the more critical areas of the World Trade Center (WTC) mass fatality of September 11, 2001. The main challenges in identifying the victims of the recent South Asian Tsunami disaster, which has produced the steepest death count rise in history, will also be considered. We also present data from two recent mass fatality cases that involved Spanish victims: the Madrid terrorist attack of March 11, 2004, and the Yakolev-42 aircraft accident in Trabzon, Turkey, of May 26, 2003.
Fine crystalline VO2 nanoparticles: synthesis, abnormal phase transition temperatures and excellent optical properties of a derived VO2 nanocomposite foil (2013)

A simulation of the optical properties of nanocomposite coatings derived from VO2 nanoparticles (NPs) shows that the nanocomposite coatings have advantages over pure VO2 thin films in their solar energy modification ability (ΔTsol) and luminous transmittance (Tlum). These nanocoatings rely on fine quality VO2 NPs; methods to prepare NPs for this purpose are yet to be developed. By studying the formation mechanism of VO2 NPs, the NP preparation process was optimized, and fine crystal quality VO2 NPs with diameters from 25–45 nm were synthesized. The highest latent heat of these VO2 NPs is 43 J g−1, which is considerably higher than the 25 J g−1 reported previously and close to the 51 J g−1 of bulk VO2, which indicates that these VO2 NPs are highly crystalline. These NPs showed an asymmetrical phase transition and increased insulator–metal transition (IMT) temperatures. According to our results, the size of particles is not the only reason that should be responsible for the increased IMT temperatures. The high-quality NPs were dispersed in polyurethane (PU) and coated on polyethylene terephthalate (PET). The relationship between the solar energy modification ability (ΔTsol) and the luminous transmittance (Tlum) was studied by experiments and simulation. Although the best experimental values of ΔTsol = 22.3% and Tlum = 45.6% are still lower than the simulation results of ΔTsol = 23.7% and Tlum = 32.4%, these values represent the best for reported VO2 smart films or coatings.