gebhart/patrepeval huggingface dataset:
Androgen Receptor CAG Repeats and Prostate Cancer (2002)

Prostate cancer is the most common nonskin malignancy and the second leading cause of cancer deaths among men in the United States. Prostate cancer ([Mendelian Inheritance in Man 176807]) has a complex etiology; presently, age, ethnicity, and family history are the most consistently reported risk factors associated with disease. Other potential risk and protective factors have also been suggested. Androgen, acting through the androgen receptor (AR) is helpful in preserving the normal function and structure of the prostate. The AR ([Mendelian Inheritance in Man 313700]) is a structurally conserved member of the nuclear receptor superfamily of ligand-activated transcription factors. Androgens, such as testosterone, are strong tumor promoters, and work with the AR to augment the effect of any carcinogens present and stimulate cell division. The CAG repeats encode long glutamine homopolymeric amino acid chains in the amino-terminal domain of the AR gene. The authors focus on CAG repeat length because recent research suggests that men with shorter AR CAG lengths (e.g., < or =22 repeats) are at a greater risk of developing prostate cancer than are those with longer variants. Among populations studied to date, African Americans appear to have the highest frequency of short CAG repeats. Several potential interactions have also been explored, including molecular interactions, androgen deprivation therapy, and prostate-specific antigen expression. CAG repeat length can be determined with high sensitivity and specificity. Presently, there is no recommended population screening for AR CAG repeat length.
The structure of hip consumerism (2001)

Critics of mass culture often identify 1950s-style status competition as one of the central forces driving consumerism. Thomas Frank has challenged this view, arguing that countercultural rebellion now provides the primary source of consumerism in our society, and that ‘cool’ has become its central ideological expression. This paper provides a rearticulation and defense of Frank's thesis, first identifying consumerism as a type of collective action problem, then showing how the ‘hip consumer’ is one who adopts a free-rider strategy in this context.
Lonidamine in metastatic breast cancer. (1991)

Lonidamine belongs to a new class of antineoplastics agents, since it does interfere with cell energy processes. When administered as single agent in metastatic breast cancer, it produces moderate therapeutic effects. The pattern of toxicity includes myalgias, asthenia, testicular pain, and gastrointestinal discomfort. No myelosuppression was demonstrated in phase I-II studies. Since the peculiar mechanism of action and side effects are not overlapping with those of standard chemotherapeutic agents, combination of lonidamine with chemotherapy is currently under investigation in advanced breast cancer. Moreover, the potentiation of radiotherapy by lonidamine could be of interest in palliating symptomatic lesions from breast cancer.
A facile synthesis of monodisperse Au nanoparticles and their catalysis of CO oxidation (2008)

Monodisperse Au nanoparticles (NPs) have been synthesized at room temperature via a burst nucleation of Au upon injection of the reducing agent t-butylamine-borane complex into a 1, 2, 3, 4-tetrahydronaphthalene solution of HAuCl4·3H2O in the presence of oleylamine. The as-synthesized Au NPs show size-dependent surface plasmonic properties between 520 and 530 nm. They adopt an icosahedral shape and are polycrystalline with multiple-twinned structures. When deposited on a graphitized porous carbon support, the NPs are highly active for CO oxidation, showing 100% CO conversion at −45 °C.
The Pharmacokinetics of Nitrofurantoin and its Related Bioavailability (2015)

Nitrofurantoin is a urinary tract antibacterial agent whose clinical effectiveness depends on the high urinary drug levels encountered during therapeutic drug dosage. Under these conditions, only low blood drug concentrations are usually found. On the basis of urinary nitrofurantoin excretion determined after oral and intravenous drug administration, orally administered nitrofurantoin in a suitable dosage form is well absorbed. In vitro testing does not accurately reflect nitrofurantoin bioavailability, which is affected by formulation differences, drug particle size, and dosage form. Nitrofurantoin is readily absorbed and quickly distributed into most body fluids. It is rapidly excreted in large amounts in bile and urine. With the exception of the active drug secretion in the kidney tubule and biliary drug transport, nitrofurantoin transfer across body membranes occurs by diffusion. Nitrofurantoin has a short elimination half-life in whole blood or plasma. In conjunction with its rapid excretion by the primary routes, there is little evidence for any prolonged binding of nitrofurantoin to either plasma proteins or tissues. The first-order kinetics involved in nitrofurantoin absorption and elimination is most appropriately described by a one-compartment open model. Biliary and urinary excretion of unchanged nitrofurantoin and enzymatic degradation are the primary means of elimination.
A subspace method for blind channel identification in OFDM systems (2002)

It has been shown that cyclostationarity in the received signal allows the receiver to blindly identify the channel impulse response using only second-order statistics. In orthogonal frequency-division multiplexing (OFDM) systems, cyclostationarity is embedded at the transmitter due to cyclic prefix. In this paper, a subspace approach based on second-order statistics is proposed for blind channel identification in OFDM systems. We derive a sufficient condition that guarantees all the channels to be identifiable no matter what their zero locations are. Computer simulations demonstrate the superior performance of the proposed algorithm over methods reported earlier in the literature.
Presentation Trainer: what experts and computers can tell about your nonverbal communication (2017)

Abstract The ability to present effectively is essential for professionals; therefore, oral communication courses have become part of the curricula for higher education studies. However, speaking in public is still a challenge for many graduates. To tackle this problem, driven by the recent advances in computer vision techniques and prosody analysis, multimodal tools have been designed to support the development of public speaking skills. One of these tools is the Presentation Trainer , a research prototype able to provide learners with real‐time feedback on a set of nonverbal communication aspects. Despite initial positive evaluations, the application still lacks grounding in a valid assessment model for nonverbal communication aspects in the context of presentations. To come up with such a model, we conducted semi‐structured interviews with experts in the public speaking domain. Furthermore, the objective of these interviews was also to have a formative evaluation of the Presentation Trainer , analysing how it suits with common practices for teaching and learning public speaking skills. The results of this study identify 131 nonverbal communication practices that affect the quality of a presentation and summarize experts' points of view regarding multimodal public speaker instructors.
The gamma-ray universe (1993)

When we gaze up at the night sky, only a small fraction of the celestial photons meet our eyes. These particles of light, radi? ating from the nearest stars, bear only modest amounts of energy. There are other photons, however, above the earth's atmosphere and beyond the eye's ability to detect them, that are bil? lions of times more energetic than light. These gamma-ray photons are the tell? tale emissaries of the most energetic events that take place in our universe. Because gamma-ray photons are ab? sorbed by the earth's atmosphere, it was not until the 1960s that they were first recorded (by balloon-borne detec? tors high in the stratosphere). Various satellites and other spacecraft with gamma-ray-detecting abilities followed on the heels of these early studies, each revealing a little more about the high energy universe. Now, after three decades of observations, an intriguing (and mystifying) picture has emerged. Prominently splashed across the gam? ma-ray sky is a diffuse emission of high energy photons that emanate from the Milky Way. A closer look tells us that other gamma rays appear to come from discrete (point) sources such as pulsars, the rapidly spinning neutron stars that are the remnants of some supernova ex? plosions. Some point sources appear to release vast amounts of gamma-ray
Electro-acupuncture of Tsusanli and Shangchuhsu regulates gastric activity possibly through mediation of the vagus-solotary complex. (2007)

Our study suggests that this electroacupuncture regulation of gastric activity may partially depend upon integrated nerve pathway and related central neurons and astrocytes in the vagus-solitary complex.
Epitaxial growth and shearing of the body centered cubic phase in diblock copolymer melts (1994)

Two poly(ethylenepropylene)–poly(ethylethylene) (PEP-PEE) diblock copolymer melts, containing 25% and 83% by volume PEP, were investigated using small-angle neutron scattering (SANS) and rheological measurements. The SANS measurements were performed with the aid of an in situ shearing device operated directly in the neutron beam. Each sample was observed to possess three equilibrium phases: two ordered phases at low temperature and a disordered phase at elevated temperatures. The low and high temperature ordered phases have been evaluated to be hexagonally packed (hex) cylinders and body centered cubic (bcc) spheres, respectively. Application of a large amplitude dynamic shear deformation to the hex phase leads to well-aligned cylinders, with a specific crystallographic orientation relative to the shear plane. Upon heating through the cylinder-to-sphere transition, the bcc phase grows epitaxially, with the [111] direction coincident with the original cylinder axis, leading to a well-defined twinned microstructure. SANS measurements performed while the bcc specimens were dynamically sheared revealed a rich compliment of microstructural rearrangements, with the twinned state appearing at low and high shear rates, and two-dimensional disordering at intermediate shear rates.
Association Between Magnesium Intake and Depression and Anxiety in Community-Dwelling Adults: The Hordaland Health Study (2009)

The hypothesis that magnesium intake is related to depression in the community is supported by the present findings. These findings may have public health and treatment implications.
Update of research on the role of EZH2 in cancer progression (2013)

Accumulating evidence shows that enhancer of zeste homolog 2 (E2H2) is upregulated in a broad range of cancer types, such as breast cancer, prostate cancer, ovarian cancer, and colon cancer. Therefore, inhibiting EZH2 expression may be a promising strategy for anticancer therapy. This review focuses on the current understanding of the mechanisms underlying EZH2 regulation that are involved in cancer progression. Also, it introduces two EZH2 inhibitors that target EZH2 and could be potentially applied in the treatment of cancer in the future.
Server capacity planning for Web traffic workload (1999)

The goal of the paper is to provide a methodology for determining bandwidth requirements for various hardware components of a World Wide Web server. The paper assumes a traditional symmetric multiprocessor (SMP) architecture for the Web server, although the same analysis applies to an SMP node in a cluster. The paper derives formulae for bandwidth demands for memory, processor data bus, network adapters, disk adapters, I/O memory paths, and I/O buses. Since the Web workload characteristics vary widely, three sample workloads are considered for illustrative purposes: 1) standard SPECweb96; 2) a SPECweb96-like workload that assumes dynamic data and retransmissions; and 3) WebProxy, which models a Web proxy server that does not do much caching, and thus has rather severe requirements. The results point to a few general conclusions regarding Web workloads. In particular, reduction in memory/data bus bandwidth by using the virtual interface architecture (VIA) is very desirable, and the connectivity needs may go well beyond the capabilities of traditional systems based on the traditional PCI-bus. Web workloads also demand a significantly higher memory bandwidth than data bus bandwidth and this disparity is expected to increase with the use of VIA. Also, the current efforts to offload TCP/IP processing may require a larger headroom in I/O subsystem bandwidth than in the processor-memory subsystem.
Deep Neural Network for Automatic Speech Recognition: from the Industry's View (2014)

Recently, a new acoustic model, referred to as the context-dependent deep neural network hidden Markov model (CD-DNN-HMM), has been developed. It has been shown, by many groups, to outperform the conventional GMM-HMMs in many automatic speech recognition (ASR) tasks. It has been widely deployed to real-world products from Microsoft, Google etc. and benefits millions of users. Given its current success, I will talk about the most important research topics of DNN in industry and how we handle these challenges by answering the following questions: 1) How to reduce the runtime cost without accuracy loss so that the user feel no latency increase when switching from GMM to DNN? 2) How to do speaker personalization with small footprint? 3) How to enable new languages with limited training data? 4) How to reduce accuracy gap between large and small DNN? 5) How to handle unseen scenario? 6) How to enable DNN to handle different factors?
Iterative algorithms based on multistage criteria for multichannel blind deconvolution (1999)

Blind deconvolution and blind equalization have been important interesting topics in diverse fields including data communication, image processing, and geophysical data processing. Recently, Inouye and Habe introduced a multistage criterion for attaining blind deconvolution of multiple-input multiple-output (MIMO) linear time-invariant (LTI) systems. In this correspondence, based on their criterion, we present iterative algorithms for solving the blind deconvolution problem of MIMO LTI systems. However, their criterion should be subjected to several constraints of equations. Therefore, they proposed a new constraint-free multistage criterion for accomplishing the blind deconvolution of MIMO LTI systems. Based on their unconstrained criterion, we show iterative algorithms for solving the blind deconvolution of multichannel LTI systems.
Preliminary study about the possible glycemic clinical advantage in using a fixed combination of Berberis aristata and Silybum marianum standardized extracts versus only Berberis aristata in patients with type 2 diabetes (2013)

The association of berberine and silymarin demonstrated to be more effective than berberine alone in reducing HbA1c, when administered at the same dose and in the form of standardized extracts in type 2 diabetic patients.
Faces engage us (2014)

Photos are becoming prominent means of communication online. Despite photos' pervasive presence in social media and online world, we know little about how people interact and engage with their content. Understanding how photo content might signify engagement, can impact both science and design, influencing production and distribution. One common type of photo content that is shared on social media, is the photos of people. From studies of offline behavior, we know that human faces are powerful channels of non-verbal communication. In this paper, we study this behavioral phenomena online. We ask how presence of a face, it's age and gender might impact social engagement on the photo. We use a corpus of 1 million Instagram images and organize our study around two social engagement feedback factors, likes and comments. Our results show that photos with faces are 38% more likely to receive likes and 32% more likely to receive comments, even after controlling for social network reach and activity. We find, however, that the number of faces, their age and gender do not have an effect. This work presents the first results on how photos with human faces relate to engagement on large scale image sharing communities. In addition to contributing to the research around online user behavior, our findings offer a new line of future work using visual analysis.
Free viewpoint browsing of live soccer games (2005)

We present a new video browsing method for multiple videos that are taken at large-scale space for live 3D events such as soccer games. By our method, multiple viewers over a computer network can browse a live 3D event from any viewpoint and each viewer can move his/her viewpoint freely. Our algorithm consists of five steps. Our system first captures videos from multiple cameras, then extracts texture segments from the videos, selects appropriate segments according to a viewpoint which is given by user dynamically, transmits them to users, and lays out the segments in virtual space so that each viewer can see the segments in a virtual environment as if the viewers were in the event. Our 3D video display system requires 10 Mbps at most to browse a soccer game. We conducted experiments at two real soccer stadiums and succeeded in realizing live realistic visualization with free viewpoint at about 26 fps.
Adjustable precision floating point arithmetic in Ada (1987)

article Free Access Share on Adjustable precision floating point arithmetic in Ada Author: Randal Leavitt PRIOR Data Sciences LTD., Kanata, Ont., Canada PRIOR Data Sciences LTD., Kanata, Ont., CanadaView Profile Authors Info & Claims ACM SIGAda Ada LettersVolume VIIIssue 5Sept./Oct. 1987 pp 63–78https://doi.org/10.1145/36077.36082Online:01 September 1987Publication History 1citation233DownloadsMetricsTotal Citations1Total Downloads233Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Spectral Ellipsometry for In Situ Real-Time Measurement and Control (1992)

*Described is a spectral ellipsometer capable of precisely measuring thicknesses and compositions of multilayer structures, in situ and in real time. This spectral ellipsometer has been applied to wafer property monitoring during remote microwave plasma etching. Thicknesses, etch rates and compositions are fed back to a process host computer in real-time for single layer or multilayer film stacks of Si3N4, Si02, SiqN4 and Si02 mixtures, polycrystalline Si. It is noteworthy that unlike many other sensing techniques, interfaces can be anticipated using ellipsometry, allowing end pointing at any desired film thickness. Standard deviations for repeat thickness measurement are better than 0.04 nm for single layer films and about 0.2 nm for individual films within multilayer stacks. Spectral ellipsometry allows over determination of variables in multilayer stacks, hence, structure models and layer ,parameters can be verified using statistical methods. Spectral information also allows self calibration of incident angles.
A Prospective Analysis of Low‐Grade Gastric MALT Lymphoma after <i>Helicobacter pylori</i> Eradication (2006)

The status of H. pylori is the most important risk factor affecting recurrence. Therefore, adequate eradication regimen and accurate regular evaluation for H. pylori status are needed during follow up of primary gastric low-grade B-cell MALT lymphoma.
Novel benzyl sulfonium salt having an aromatic group on sulfur atom as a latent thermal initiator (1991)

Abstract Three benzyl p ‐hydroxyphenyl methylsulfonium salts with different counter anions were synthesized as novel latent thermal initiators. Syntheses of the sulfonium salts ( 2 ) were performed by the reaction of p ‐hydroxyphenyl methyl sulfide with benzyl chloride followed by exchange of the counter anion (Cl − ) with SbF − 6 ( 2a ), PF − 6 ( 2b ), or BF − 4 ( 2c ). In the bulk polymerization of glycidyl phenyl ether (PGE) with 2 , initiator activity of the sulfonium salts was evaluated by comparison with that of benzyl tetramethylenesulfonium hexafluoroantimonate ( 1 , R = H). Among the initiators, 2a showed the highest activity, and was much more active than 1 (R = H). Since the polymerization of PGE with 2a proceeded efficiently at more than 80°C but not at all at less than 60°C, 2a was suggested to be a good latent thermal initiator.
Heat transfer research for ocean thermal energy conversion (1987)

In this lecture an overview of the heat- and mass-transfer phenomena of importance in ocean thermal energy conversion (OTEC) is presented with particular emphasis on open-cycle OTEC systems. Also included is a short historical review of OTEC developments in the past century and a comparison of open- and closed-cycle thermodynamics. Finally, results of system analyses, showing the effect of plant size on cost and the near-term potential of using OTEC for combined power production and desalination systems are briefly discussed.
Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian (2008)

Blue-flowered gentian (Gentiana triflora) is known to accumulate gentiodelphin, a unique polyacylated delphinidin-type anthocyanin, in the petals. Almost all of the structural genes involved in gentiodelphin biosynthesis have been isolated, but an important gene encoding UDP-glucose:anthocyanin 5-O-glucosyltransferase (5GT) remained to be identified. In this study, an attempt was made to isolate and characterize gentian 5GT, which is responsible for glucosylation of anthocyanidin 3-glucoside. A PCR-based cloning strategy identified seven 5GT candidates from gentian flowers. Among them, the deduced amino acid sequence of the 5GT gene from gentian petal cDNA, designated Gt5GT7, exhibited 36.0-41.7% identities with those of 5GTs from other plant species, and phylogenic analysis also suggested that Gt5GT7 belongs to the 5GT subfamily. The expression analysis showed that Gt5GT7 transcripts were detected predominantly in petals and weakly in filaments but not in leaves, stems, and other floral organs. In addition, increased levels of Gt5GT7 transcripts in petals coincided with flower development, a pattern identical to that of 5GT enzymatic activity as determined by in vitro assay using petal crude proteins. The substrate specificity of Gt5GT7 was analysed in vitro using the recombinant enzyme produced by Escherichia coli. Gt5GT7 could transfer a glucosyl moiety to anthocyanidin 3-glycosides but not to other flavonoid compounds. Delphinidin 3-glucoside, the precursor of gentiodelphin, was the best substrate among several anthocyanidin 3-glycosides tested. Heterologous expression of Gt5GT7 in tobacco plants led to additional accumulation of cyanidin 3-rutinoside-5-glucoside, confirming that Gt5GT7 has a valid enzymatic activity in planta.
123 PIC Microcontroller Experiments for the Evil Genius (2005)

Microchip continually updates its product line with more capable and lower cost products. They also provide excellent development tools. Few books take advantage of all the work done by Microchip. 123 PIC Microcontroller Experiments for the Evil Genius uses the best parts, and does not become dependent on one tool type or version, to accommodate the widest audience possible. Building on the success of 123 Robotics Experiments for the Evil Genius, as well as the unbelievable sales history of Programming and Customizing the PIC Microcontroller, this book will combine the format of the evil genius title with the following of the microcontroller audience for a sure-fire hit.