gebhart/patrepeval huggingface dataset:
(−)-Cytisine and Derivatives: Synthesis, Reactivity, and Applications (2013)

International audience
Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. (2009)

Curcuma longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Turmeric constituents include the three curcuminoids: curcumin (diferuloylmethane; the primary constituent and the one responsible for its vibrant yellow color), demethoxycurcumin, and bisdemethoxycurcumin, as well as volatile oils (tumerone, atlantone, and zingiberone), sugars, proteins, and resins. While numerous pharmacological activities, including antioxidant and antimicrobial properties, have been attributed to curcumin, this article focuses on curcumin's anti-inflammatory properties and its use for inflammatory conditions. Curcumin's effect on cancer (from an anti-inflammatory perspective) will also be discussed; however, an exhaustive review of its many anticancer mechanisms is outside the scope of this article. Research has shown curcumin to be a highly pleiotropic molecule capable of interacting with numerous molecular targets involved in inflammation. Based on early cell culture and animal research, clinical trials indicate curcumin may have potential as a therapeutic agent in diseases such as inflammatory bowel disease, pancreatitis, arthritis, and chronic anterior uveitis, as well as certain types of cancer. Because of curcumin's rapid plasma clearance and conjugation, its therapeutic usefulness has been somewhat limited, leading researchers to investigate the benefits of complexing curcumin with other substances to increase systemic bioavailability. Numerous in-progress clinical trials should provide an even deeper understanding of the mechanisms and therapeutic potential of curcumin.
Cloning of the Bacillus subtilis DLG beta-1,4-glucanase gene and its expression in Escherichia coli and B. subtilis (1986)

The gene encoding beta-1,4-glucanase in Bacillus subtilis DLG was cloned into both Escherichia coli C600SF8 and B. subtilis PSL1, which does not naturally produce beta-1,4-glucanase, with the shuttle vector pPL1202. This enzyme is capable of degrading both carboxymethyl cellulose and trinitrophenyl carboxymethyl cellulose, but not more crystalline cellulosic substrates (L. M. Robson and G. H. Chambliss, Appl. Environ. Microbiol. 47:1039-1046, 1984). The beta-1,4-glucanase gene was localized to a 2-kilobase (kb) EcoRI-HindIII fragment contained within a 3-kb EcoRI chromosomal DNA fragment of B. subtilis DLG. Recombinant plasmids pLG4000, pLG4001a, pLG4001b, and pLG4002, carrying this 2-kb DNA fragment, were stably maintained in both hosts, and the beta-1,4-glucanase gene was expressed in both. The 3-kb EcoRI fragment apparently contained the beta-1,4-glucanase gene promoter, since transformed strains of B. subtilis PSL1 produced the enzyme in the same temporal fashion as the natural host B. subtilis DLG. B. subtilis DLG produced a 35,200-dalton exocellular beta-1,4-glucanase; intracellular beta-1,4-glucanase was undetectable. E. coli C600SF8 transformants carrying any of the four recombinant plasmids produced two active forms of beta-1,4-glucanase, an intracellular form (51,000 +/- 900 daltons) and a cell-associated form (39,000 +/- 400 daltons). Free exocellular enzyme was negligible. In contrast, B. subtilis PSL1 transformed with recombinant plasmid pLG4001b produced three distinct sizes of active exocellular beta-1,4-glucanase: approximately 36,000, approximately 35,200, and approximately 33,500 daltons. Additionally, B. subtilis PSL1(pLG4001b) transformants contained a small amount (5% or less) of active intracellular beta-1,4-glucanase of three distinct sizes: approximately 50,500, approximately 38,500 and approximately 36,000 daltons. The largest form of beta-1,4-glucanase seen in both transformants may be the primary, unprocessed translation product of the gene.
Molecular insights into the selective action of a magnetically removable complexone-grafted adsorbent (2014)

The binding and release of trivalent rare earth element (REE) cations (Dy(3+), Nd(3+) and La(3+)) from solutions by a new fully characterized magnetic nano adsorbent material, consisting of iminodiacetic acid ligand (H2IDA) grafted onto SiO2 covered γ-Fe2O3 nanoparticles, was investigated. The nano adsorbent revealed a slightly higher capacity towards heavier REE and appreciable selectivity, especially on desorption. It was found that the composition of the surface complex was RE(3+) : L = 1 : 1. The complexation of the molecular H2IDA with RE(3+) in this ratio under non-basic conditions was therefore investigated by X-ray crystallography to produce relevant molecular models. Unexpectedly big differences in coordination numbers and binding mode of IDA along with distinct analogies in packing of the ligand molecules in the obtained 2D-coordination polymer structures provided valuable insights into possible reasons for the observed selectivity.
Corneal and Epithelial Thickness Changes After 4 Weeks of Overnight Corneal Refractive Therapy Lens Wear, Measured With Optical Coherence Tomography (2004)

This study shows that CRT lenses induce differential overnight swelling across the cornea, with rapid deswelling during the day. Central epithelial thinning and paracentral thickening occurs, with recovery 3 days after discontinuation of lens wear.
Human Immunodeficiency Virus (HIV) DNA Load and Level of Immunosuppression in Treatment‐Naive HIV‐1–Infected Patients (2003)

Prognostic value of baseline human immunodeficiency virus type 1 DNA measurement for disease progression in patients receiving nucleoside therapy.
청년정책 거버넌스의 네트워크 구조 분석 (2018)

The purpose of this study is to suggest a policy direction to promote youth policy governance. This research analyzed youth policy governance focused...
Dielectrics in Electric Fields (1956)

RETURN TO ISSUEPREVNewsNEXTDielectrics in Electric FieldsThey rise and flow; nonmechanical pumps and switches are among potential applicationsCite this: Chem. Eng. News 1956, 34, 20, 2370–2372Publication Date (Print):May 14, 1956Publication History Published online5 November 2010Published inissue 14 May 1956https://doi.org/10.1021/cen-v034n020.p2370Copyright © 1956 AMERICAN CHEMICAL SOCIETYArticle Views3Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (382 KB) SUBJECTS:Insulators,Liquids Get e-Alerts
An Ultrastructural Study of First‐ and Second‐Generation Merogony in the Coccidian Sarcocystis tenella<sup>1</sup> (1981)

Sporocysts of the coccidian Sarcocystis tennella were originally isolated in the feces of a coyote. Sporocysts used for inoculation of lambs were obtained from experimentally infected dogs. At 14, 16, and 19 days postinoculation (DPI) of lambs with the sporocysts, various developmental stages of first-generation meronts were found within cells located between the endothelium and internal elastic membrane of mesenteric arteries. At 19, 21, and 25 DPI, second-generation merogony occurred in cells associated with capillaries and arterioles of kidney glomeruli and convoluted tubules. Meronts of both generations were bounded by a double pellicular membrane and were situated free in the host cell cytoplasm. Merozoites formed by endopolygeny that involved multiple intranuclear spindles of a single, large irregular nucleus. First-generation meronts measured 22.6 x 17.1 micrometers (19-29.7 x 7.5-24 micrometers) and contained 120-240 merozoites, which measured 7.1 x 1.6 micrometers (4.8-7.5 x 1.3-1.8 micrometers). Corresponding values for second-generation meronts were 13.2 x 9.2 micrometers (8.3-15 x 7-13.5 micrometers), 32-80, and 5.8 1.7 micrometers (5.6-6.2 x 1.4-2.2 micrometers).
Geo-fence driven crowd-sourcing for emergencies (2015)

For some emergency situations an effective response can be reliant on sensor data (e.g. river level, traffic flow, weather conditions) to provide situation awareness, in order to help authorities make informed decisions. Gathering data in a traditional approach, i.e. using precise physical sensors, is a highly expensive task, involving procurement, installation and maintenance of a number of sensors. As a result, the coverage of sensors is limited and only the regions deemed most important by authorities are monitored. However, regions currently not being monitored can have an urgent need to be sensed depending on emergencies or situations. We present a high-level overview of the Locaware system, which employs a flexible geofencing approach to enable crowdsourcing by requesting citizens and volunteers to help authorities formulate a greater situation awareness of a region under consideration. While the Locaware system is motivated for water monitoring, our approach can be applied in other contexts.
QBF-Based Synthesis of Optimal Word-Splitting in Approximate Multi-Level Storage Cells (2014)

In applications such as multimedia that tolerate imprecise re-sults, approximate computing techniques can sacrifice pre-cision to save power or time. One aspect of approximate computing is imprecise storage in multi-level cells (MLCs). Computer words that are too large for a single MLC must be distributed across multiple approximate MLCs. The word-level imprecision depends on how the words are split across the MLCs. This work gives an automated synthesis approach for splitting words across MLCs. Given bounds on the im-precision of individual MLCs, the technique synthesizes so-lutions for splitting words across cells to minimize the worst-case imprecision at the word level. The technique is based on quantified Boolean formula solving, within an overall opti-mization loop. Worst-case word-level error is shown to vary by over an order of magnitude across otherwise comparable word-splitting alternatives.
Enhanced Electrical Conductivity of Silver Nanoparticles for High Frequency Electronic Applications (2012)

An enhancement in the electrical performance of low temperature screen-printed silver nanoparticles (nAg) has been measured at frequencies up to 220 GHz. We show that for frequencies above 80 GHz the electrical losses in coplanar waveguide structures fabricated using nAg at 350 °C are lower than those found in conventional thick film Ag conductors consisting of micrometer-sized grains and fabricated at 850 °C. The improved electrical performance is attributed to the better packing of the silver nanoparticles resulting in lower surface roughness by a factor of 3. We discuss how the use of silver nanoparticles offers new routes to high frequency applications on temperature sensitive conformal substrates and in sub-THz metamaterials.
Synthesis of Pyridine Derivatives. VIII (1957)

A few 2-pyridinealdehydes, with nitro, methoxy, and chlorine in the 4-position of the pyridine ring were prepared from 2-picoline or 2, 6-lutidline through its 1-oxides. Tests on their thiosemicarbazides in inhibiting the growth of tubercle bacilli were described.
Channel Codes (2009)

Channel coding lies at the heart of digital communication and data storage, and this detailed introduction describes the core theory as well as decoding algorithms, implementation details, and performance analyses. In this book, Professors Ryan and Lin provide clear information on modern channel codes, including turbo and low-density parity-check (LDPC) codes. They also present detailed coverage of BCH codes, Reed-Solomon codes, convolutional codes, finite geometry codes, and product codes, providing a one-stop resource for both classical and modern coding techniques. Assuming no prior knowledge in the field of channel coding, the opening chapters begin with basic theory to introduce newcomers to the subject. Later chapters then extend to advanced topics such as code ensemble performance analyses and algebraic code design. 250 varied and stimulating end-of-chapter problems are also included to test and enhance learning, making this an essential resource for students and practitioners alike.
ChemInform Abstract: SYNTHESIS OF ACTINOMYCIN ANALOGS. XII. 4,6‐BIS(ACETYLAMINO)CINNABARINIC ACID AND ITS DERIVATIVES (1982)

Abstract Durch selektive Reduktion des Dinitroderivats (I) mit (NH 4 ), Swird das Aminonitroderivat (II) erhalten.
Standardization of Digger Derrick Capacity Ratings (1983)

<div class="htmlview paragraph">Utility digger derricks are usually classified by their capacity rating with the booms fully retracted and fully elevated. This is not a practical working position. A more meaningful comparison of useful lifting capacities can be made when the rating classification is the load which can be lifted by the digger derrick lift cylinder at a ten foot load radius. Lifting capacities at lower boom angles are also important for digger derrick applications.</div>
Studies on the diastereoisomeric and conformational aspects of benzoyl dipeptide esters, as a means of assessing racemisation using nuclear magnetic resonance spectroscopy (1981)

Distinct methyl ester signals in the 1H n.m.r. spectra of diastereoisomeric forms of benzoyl dipeptide methyl esters provide a means of estimating the isomer composition of diastereoisomeric mixtures. Analysis of the mixture derived from peptide-coupling reactions using this n.m.r. technique provides a convenient means of comparing the racemisation potential of a series of coupling reagents. Significant asymmetric induction accompanies racemisation during the model peptide couplings. Conformational effects have been studied using 13C n.m.r. spectroscopy and the structural criteria for observing diastereoisomeric ester signals in the 1H n.m.r. spectra have been rationalised.
The Complete Guide to High-End Audio (1995)

An updated edition of what many consider the "bible of high-end audio" In this newly revised and updated fifth edition, Robert Harley, editor in chief of the Absolute Sound magazine, tells you everything you need to know about buying and enjoying high-quality hi-fi. With this book, discover how to get the best sound for your money, how to identify the weak links in your system and upgrade where it will do the most good, how to set up and tweak your system for maximum performance, and how to become a more perceptive and appreciative listener. Just a few of the secrets you will learn cover hi
Fault diagnosis and augmented reality-based troubleshooting of HVAC systems (2016)

Maintaining Heating, ventilating and air conditioning (HVAC) systems in buildings and vehicles in superior condition is essential to energy waste minimization, increased equipment availability and improved thermal comfort of occupants. HVAC systems are complex interconnected systems. Consequently, early detection and diagnosis of incipient faults in such systems using robust methodologies and tools is salient for achieving thermal comfort. The increased complexity, cross-subsystem fault propagation, and the associated information propagation delays in networked HVAC systems makes fault diagnosis and maintenance a challenging task. This motivates us to incorporate the emerging technologies, such as real-time monitoring, remote diagnosis and augmented reality (AR) technologies, for efficient fault diagnosis and troubleshooting in such systems. This paper presents an integrated AR-based framework to monitor an HVAC system (or any cyber-physical system) in real-time, access system health information remotely and act on that information proactively to prevent or minimize the system down time.
Design of a thermal print head for high‐speed and high‐resolution printing (1992)

Abstract Thermal analysis of a thin‐film thermal print head was carried out with the aim of obtaining guidelines for the design of a print head for high‐speed and high‐resolution printing. The analysis showed that if current is passed through the heating resistors for a short period, there will be a time lag between the temperature increase in the resistors and the temperature increase in the heat sensitive paper. Furthermore, although a short pulse is preferable for high‐resolution printing, there is a point beyond which further decrease in the duration of the pulse has little effect. It was estimated that changes to the heat insulation layer and protective film alone would not lead to an improvement in the performance of the print head as a whole. The printing test yielded the same results as those provided by the thermal analysis. For example, a pulse duration of 5 ms is not preferable for a resolution of 16 dots/mm. However, the contrast obtained with a pulse duration of 0.3 ms may also be obtained with a pulse duration of 0.8 ms.
The economic advantages and disadvantages of energy product licensing (1984)

This paper serves to discuss the economic aspects of energy product licensing and to delineate the pros and cons of such licensing. A licensor is well advised to weigh these factors before proceeding with the licensing of an energy product and be certain that the potential drawbacks are significantly outweighed by the anticipated advantages of licensing. Correspondingly, consideration must also be given to the advantages and disadvantages of licensing by the licensee and the international impact of licensing energy products should be understood before a decision to grant or receive a license should be made.
Constructivismo en el aula (2009)

This article talks about a didactic proposal in maths to work with a student with special educational needs without comprehensive reading in first grade in high school. It explains the symbols > “bigger than” and and <, after she verbalises them “bigger than” and “smaller than” and later she uses pictures. She shows that this student works better with examples taken from his closest reality, this way he constructs new concepts over previous concepts.
Processor group membership protocols: specification, design and implementation (2002)

The specification, design and implementation of a set of protocols to solve the processor group membership problem in distributed systems are presented. These group membership protocols were developed as part of a toolkit for building distributed/parallel applications on a cluster of workstations. The group membership service forms the lowest layer in the toolkit, and is the glue which unifies all other layers. The membership service supports three distinct protocols: weak, strong, and hybrid. These protocols differ significantly in the level of consistency and the number of messages exchanged in reaching agreement. The modular implementation of these protocols and the optimization techniques used to enhance their performance are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Pulping Bagasse with Alcholic Nitric Acid Pulp Yields and Characteristics (1938)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPulping Bagasse with Alcholic Nitric Acid Pulp Yields and CharacteristicsS. I. Aronovsky and D. F. J. LynchCite this: Ind. Eng. Chem. 1938, 30, 7, 790–795Publication Date (Print):July 1, 1938Publication History Published online1 May 2002Published inissue 1 July 1938https://pubs.acs.org/doi/10.1021/ie50343a016https://doi.org/10.1021/ie50343a016research-articleACS PublicationsRequest reuse permissionsArticle Views42Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Cooperation of Biological and Mechanical Signals in Cardiac Progenitor Cell Differentiation (2010)

Three-dimensional cardiac tissue-specific scaffolds made of poly-lactic acid (PLA) have an ordered array of square pores reproducing anisotropic cardiac-like stiffness. The mechano-physical features of the scaffolds favor cardiomyocyte adhesion and survival and combined with biological signals released by neonatal cardiomyocytes can accelerate cardiac stem cell differentiation by emulating in vitro cardiac niche. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Converting human pluripotent stem cells into β-cells: recent advances and future challenges (2010)

Advances over the last decade suggest that generating functional beta-cells from human PSCs is achievable. However, there are aspects of beta-cell development that are not well understood and are hampering generation of PSC-derived beta-cells. In particular, the signaling pathways that instruct endocrine progenitor cells to differentiate into mature and functional beta-cells are poorly understood. Other significant obstacles remain, including the need for safe and cost-effective differentiation methods for large-scale generation of transplantation quality beta-cells, methods to prevent immune rejection of grafted tissues, and amelioration of the risks of tumorigenesis.
Role of Porphyromonas gingivalis protease activity in colonization of oral surfaces (1996)

Cysteine proteases, including Arg-gingipain of Porphyromonas gingivalis, have been implicated as important virulence factors in periodontal diseases. These enzymes are also involved in the hemagglutinating activity of the organisms. In order to determine the role of proteases in the colonization of the gingival margin, we have compared the attachment properties of P. gingivalis 381 with those of its Arg-gingipain-defective mutant, G-102. Interactions with gram-positive bacteria, human oral epithelial cells, extracellular matrix proteins, and type I collagen were evaluated. In all cases, mutant G-102 was deficient in attachment relative to the parental strain. The mutant's defects could be explained, in part, by the weak autoaggregation displayed by the mutant, which appeared to result from altered fimbrial expression. Both Western blot (immunoblot) and Northern (RNA) blot analyses indicated reduced expression of the major 43-kDa fimbrillin subunit in the mutant. These results suggest that Arg-gingipain may play both direct and indirect roles in the colonization of the gingival margin. In addition, fimbriae may play a direct role in interacting with some host surfaces.