gebhart/patrepeval huggingface dataset:
Two types of peak emotional responses to music: The psychophysiology of chills and tears (2017)

People sometimes experience a strong emotional response to artworks. Previous studies have demonstrated that the peak emotional experience of chills (goose bumps or shivers) when listening to music involves psychophysiological arousal and a rewarding effect. However, many aspects of peak emotion are still not understood. The current research takes a new perspective of peak emotional response of tears (weeping, lump in the throat). A psychophysiological experiment showed that self-reported chills increased electrodermal activity and subjective arousal whereas tears produced slow respiration during heartbeat acceleration, although both chills and tears induced pleasure and deep breathing. A song that induced chills was perceived as being both happy and sad whereas a song that induced tears was perceived as sad. A tear-eliciting song was perceived as calmer than a chill-eliciting song. These results show that tears involve pleasure from sadness and that they are psychophysiologically calming; thus, psychophysiological responses permit the distinction between chills and tears. Because tears may have a cathartic effect, the functional significance of chills and tears seems to be different. We believe that the distinction of two types of peak emotions is theoretically relevant and further study of tears would contribute to more understanding of human peak emotional response.
Amino-terminal sequence of glycoprotein D of herpes simplex virus types 1 and 2 (1984)

Glycoprotein D (gD) of herpes simplex virus is a structural component of the virion envelope which stimulates production of high titers of herpes simplex virus type-common neutralizing antibody. We carried out automated N-terminal amino acid sequencing studies on radiolabeled preparations of gD-1 (gD of herpes simplex virus type 1) and gD-2 (gD of herpes simplex virus type 2). Although some differences were noted, particularly in the methionine and alanine profiles for gD-1 and gD-2, the amino acid sequence of a number of the first 30 residues of the amino terminus of gD-1 and gD-2 appears to be quite similar. For both proteins, the first residue is a lysine. When we compared our sequence data for gD-1 with those predicted by nucleic acid sequencing, the two sequences could be aligned (with one exception) starting at residue 26 (lysine) of the predicted sequence. Thus, the first 25 amino acids of the predicted sequence are absent from the polypeptides isolated from infected cells.
Corrosion Factors of Waterwall Tube and Protection by Field Metal Spraying in Municipal Refuse Incineration Plant (1995)

Abstract In order to prevent high temperature corrosion of waterwall tubes in waste incineration boilers, fireside corrosion factors were investigated. Important factors accelerating corrosion were considered to be heavy metal (Zn, Pb) chlorides, unburned carbon included in deposits, and reducing gas atmosphere formed by increasing of unburned gas components and decreasing of O2. It is confirmed by laboratory corrosion test that increasing these factors mentioned above increased the corrosion rate of carbon steel. These tendencies were in good agreement with those in actual furnaces. Furthermore, as a corrosion prevention method, a gas spray coating of two-layer Al/80Ni20Cr, selected by laboratory corrosion test, was applied on waterwall tubes on site. The Al/80Ni20Cr spray coating maintained excellent durability for more than three years, and the effectiveness as a corrosion prevention method was confirmed. This coating system has now been applied at five plants. In this case, main deterioration factors of the coating layer were considered to be the formation of corrosion scale and the decreasing of bonding strength at the boundary surface between coating layer and base metal due to penetration of corrosive gas components through blow holes in the coating layer.
EGF stimulates the processing and export of a secreted form of EGF receptor (1990)

Human A431 cells express a 100 kDa EGF-receptor homolog that contains only the external domain. The kinetics of its maturation and export are slow and comparable to those of the transmembrane receptor. Here we demonstrate that exogenously added EGF stimulates post-translational processing and export of this receptor through a pathway that is insensitive to inhibitors of protein synthesis. The results suggest that EGF may influence one or more of the rate determining steps that control receptor export from endoplasmic reticulum. This may constitute one of the pathways by which EGF regulates the expression of its receptor.
BloomStream: Data Temperature Identification for Flash Based Memory Storage Using Bloom Filters (2018)

Data temperature identification is an importance issue of many fields like data caching and storage tiering in modern flash-based storage systems. With the technological advancement of memory and storage, data temperature identification is no longer just a classification of hot and cold, but instead becomes a "multistreaming" data categorization problem to classify data into multiple categories according to their temperature. Therefore, we propose a novel data temperature identification scheme that adopts bloom filters to efficiently capture both frequency and recency of data blocks and accurately identify the exact data temperature for each data block. Moreover, in bloom filter data structure we replace the original OR operation with the XOR masking operation such that our scheme can delete or reset bits in bloom filters and thus avoid high false positives due to saturation. We further utilize twin bloom filters to alternatively keep unmasked clean copies of data and thus ensure low false negative rate. Our extensive evaluation results show that our new scheme can accurately identify the exact data temperature with low false identification rates across different synthetic and real I/O workloads. More importantly, our scheme consumes less memory space compared to other existing data temperature identification schemes.
SrTiO 3 -based metal–insulator–semiconductor heterostructures (2001)

We explored the feasibility of employing strontium titanate (SrTiO3) as semiconducting material in field-effect metal–insulator–semiconductor epitaxial heterostructures. This idea was suggested by the observation of a dramatic effect of the oxygen deficiency on SrTiO3−δ transport properties, which brings about metallic behavior with low-temperature mobility values comparable with those commonly found for silicon. By pulsed-laser deposition, we realized patterned field-effect devices, showing a resistance enhancement up to 90%. This promising result could open perspectives for crystalline-oxide electronics.
Pearson′s chemical hardness, heterolytic dissociative version of Pauling′s bond-energy equation and a novel approach towards understanding Pearson′s hard–soft acid–base principle (1991)

The empirical chemical hardness parameters developed recently by Pearson have been examined critically. It was found that these parameters normally characterise a group but not the corresponding ion as postulated. Equation (i) has been found quite successful when the heterolytic dissociation of D(A+B–)–½[D(A+A–)+D(B+B–)]= 2|Δγ|2(i) AB into A++ B– follows the general notion of electronegativity (i.e. the more electronegative part of AB dissociates as the anion), where D(A+B–) is the energy required to dissociate the AB bond into A++ B– and D(A+A–) and D(B+B–) are the heterolytic bond-dissociation energies of the molecules AA and BB respectively. Equation (i) has been used to define a new parameter γ, where |Δγ|=|γA+–γB–|. The γ parameters characterise the ions, and have been used to rank various monovalent anions and cations in a unified way to explain the hard–soft acid–base principle of Pearson. It was found that a reaction of type (II) proceeds from left to right in the gas phase if the AB + CD → AC + BD (ii)|ΔΔγ| value of the right-hand side is greater than that of the left. Out of some 282 gas-phase reactions considered, there are few exceptions. Emphasis has been placed on explaining the course of inorganic reactions. It is felt that the γ parameter can be identified with the chemical hardness of an ion.
Morphological analysis of P-wave in patients prone to atrial fibrillation (2006)

Aim of this study was to present a P-wave model, based on a linear combination of Gaussian functions, to quantify morphological aspects of Pwave in patients prone to atrial fibrillation. Five minutes ECG recordings were performed in 25 patients with permanent dual chamber pacemakers set at 40/min in order to have spontaneous beats. ECG signals were acquired using a 32-lead mapping system for high-resolution biopotential measurement (ActiveTwo, Biosemi, The Netherlands, sample frequency 2 kHz, 24 bit resolution). Four healthy subjects were also recorded as a control group. Up to 8 Gaussian models have been computed for each averaged P-wave extracted from every lead. The P-wave morphology is then evaluated by the following parameters: best model orders @ degrees of freedom adjusted R-square (AdjRsq) =97.5%; minimum (sigmamin) and maximum (sigmamax) standard deviation of the Gaussians included in the model, number of relative maxima and minima (max+min), and zeroes of the fit. Significant differences in the best model order were obtained between the control group and patients group. Accordingly, the number of relative maxima and minima was higher in the patient group. These parameters might all be markers of the fractionated electrical activity that characterizes paroxysmal AF patients in sinus rhythm
Speech Interpolation in Digital Transmission Systems (1974)

In a telephone conversation a channel is activated by the voice only 25 percent of the time. It is therefore possible to provide a number of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</tex> connections with a number of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</tex> channels, where <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</tex> is less than <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</tex> . When the number of connections is large, <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m/n</tex> (gain) tends to the inverse of the activity. The interpolation procedures used in overload conditions and the resulting degradations, as well as the typical circuits of a voice interpolation apparatus, are examined. Also, two very highly interesting developments are herein illustrated, the ATIC equipment and a single-channel digital speech interpolation (DSI) developed only for measurement purposes. The results obtained from measurement studies carried out with the aforementioned apparatus have enabled the determination of the criteria which must be followed in the selection of the most suitable interpolation procedures. Besides examining the complexity and the reliability which the DSI equipment calls for, it has been possible to analyze the precise working characteristics under normal operating conditions.
Synthesis of Furo[2,3‐<i>c</i>]isoquinoline Derivatives (1978)

Abstract 2‐Methylfuro [2,3‐ c ] isoquinolin‐5(4 H )one (X) and 1‐phenylfuro[2,3‐ c ] isoquinolin‐5(4 H )one (XI) were prepared from thermal cyelization via the Curtius rearrangement of 5‐methyl‐3‐phenyl‐2‐furoyl azide (VI) and 3,4‐diphenyl‐2‐furoyl azide (VII), respectively. Stability against acid, alkylation and conversion of the NHCO group to a C=N double bond of X and XI, which were synthesized, are described. Also, 5‐substituted furo[2,3‐ c ] isoquinolines (XVIIIa‐c) and (XIXa‐c) were prepared.
Physicochemical and Pharmacokinetic Characterization of Amorphous Solid Dispersion of Tranilast with Enhanced Solubility in Gastric Fluid and Improved Oral Bioavailability (2012)

In the present study, amorphous solid dispersion (ASD) formulations of tranilast (TL) with 8 hydrophilic polymers were prepared by a solvent evaporation method with the aim of improving dissolution behavior in gastric fluid and thereby enhancing oral bioavailability. The physicochemical properties were characterized with a focus on morphology, crystallinity, thermal behavior, dissolution, drug-polymer interaction, and stability. Of all TL formulations, ASD formulation with Eudragit EPO exhibited the highest improvement in dissolution behavior with a 3,000-fold increase in the first-order dissolution rate under acidic conditions (pH 1.2). Spectroscopic studies using infrared and near-infrared analyses revealed the drug-polymer interaction in the Eudragit EPO-based ASD formulation. On the basis of dissolution, crystallinity, and stability data, the maximum allowable drug load in the Eudragit EPO-based ASD formulation was deduced to be ca. 50%. Pharmacokinetic profiling of orally dosed TL formulations in rats was also carried out using UPLC/ESI-MS. After oral administration of the Eudragit EPO-based ASD formulation in rats, enhanced TL exposure was observed with an increase of oral bioavailability by 19-fold, and the variation of AUC was ca. 4 times lower than that with crystalline TL. With these data, the ASD approach could be a viable formulation strategy for enhancing the wettability and oral bioavailability of TL, resulting in improved therapeutic potential of TL for the treatment of inflammatory diseases.
Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice (2001)

Heme oxygenase-1 (HO-1) is induced by a variety of conditions associated with oxidative stress. We demonstrated that mildly oxidized LDL markedly induces HO-1 in human aortic endothelial and smooth muscle cell cocultures and that its induction results in the attenuation of monocyte chemotaxis resulting from treatment with mildly oxidized LDL in vitro. To elucidate the role of HO-1 in the development of atherosclerotic lesions in vivo, we modulated HO-1 expression in LDL-receptor knockout mice fed high-fat diets. During 6-week high-fat diet trials, intraperitoneal injections of hemin (H group) or hemin and desferrioxamine (HD group) to induce HO-1, Sn-protoporphyrin IX to inhibit HO-1 (Sn group), and saline as control (C group) were performed. Both the H and HD groups showed significantly less mean atherosclerotic lesions in the proximal aorta compared with the C group, whereas the Sn group showed larger lesion compared with the C group. Modulation of HO expression and HO activities were confirmed by Northern blot analysis and HO activity assay. Immunohistochemical studies revealed significant HO-1 expression in atherosclerotic lesions, where oxidized phospholipids also localized. Major cell types expressing HO-1 were macrophages and foam cells in the lesions. HO modulations affected plasma lipid hydroperoxide (LPO) levels and nitrite/nitrate levels. These results suggest that HO-1, induced under hyperlipidemia, functioned as an intrinsic protective factor against atherosclerotic lesion formation, possibly by inhibiting lipid peroxidation and influencing the nitric oxide pathway.
Cavity squeezing by a quantum conductor (2015)

Hybrid architectures integrating mesoscopic electronic conductors with resonant microwave cavities have a great potential for investigating unexplored regimes of electron-photon coupling. In this context, producing nonclassical squeezed light is a key step towards quantum communication with scalable solid-state devices. Here we show that parametric driving of the electronic conductor induces a squeezed steady state in the cavity. We find that squeezing properties of the cavity are essentially determined by the electronic noise correlators of the quantum conductor. In the case of a tunnel junction, we predict that squeezing is optimized by applying a time-periodic series of quantized $\delta-$peaks in the bias voltage. For an asymmetric quantum dot, we show that a sharp Leviton pulse is able to achieve perfect cavity squeezing.
LA GESTIÓN ADMINISTRATIVA DE LA EMPRESA PACHECO HIDALGO TRANSPORTES & SERVICIOS S.A Y SU INCIDENCIA EN LOS RESULTADOS ECONÓMICOS DURANTE EL AÑO 2014 (2018)

El transporte terrestre de carga pesada en la economia nacional ecuatoriana tiene gran importancia, debido al hecho que por medio del transporte se pueden distribuir los productos que las industrias originan; la movilizacion de estos se da dentro y fuera de la provincia con la finalidad de dar abastecimiento de todos sus habitantes, permitiendo que sea un transporte rapido y adecuado. Conociendo la importancia que tiene el transporte terrestre de carga pesada en el Ecuador surge la presente investigacion cuya caracteristica principal es conocer y evaluar la gestion administrativa y la incidencia en los resultados economicos en la Compania Pacheco Hidalgo Transportes & Servicios S.A. La investigacion se baso en el analisis de leyes, reglamentos, ordenanzas y resoluciones a las que esta sujeta la actividad del transporte pesado, con la finalidad de poner en conocimiento de todos los interesados. Los resultados obtenidos durante el proceso de la auditoria fueron determinar las fortalezas y debilidades de la empresa, para que estos sean entregados a los directivos de la Compania y asi puedan aplicar las siguientes recomendaciones emitidas: como la definicion de una planificacion estrategica, estructura organizacional adecuada a las necesidades de la entidad, capacitacion al personal, control sobre los procesos, implementacion de manuales, entre otros, que permitiran a la Compania mantener una mejor gestion de sus recursos y establecer la mejora continua.
Combining the mapping Hamiltonian linearized semiclassical approach with the generalized quantum master equation to simulate electronically nonadiabatic molecular dynamics (2019)

The generalized quantum master equation (GQME) provides a powerful framework for simulating electronically nonadiabatic molecular dynamics. Within this framework, the effect of the nuclear degrees of freedom on the time evolution of the electronic reduced density matrix is fully captured by a memory kernel superoperator. In this paper, we consider two different procedures for calculating the memory kernel of the GQME from projection-free inputs obtained via the combination of the mapping Hamiltonian (MH) approach and the linearized semiclassical (LSC) approximation. The accuracy and feasibility of the two procedures are demonstrated on the spin-boson model. We find that although simulating the electronic dynamics by direct application of the two LSC-based procedures leads to qualitatively different results that become increasingly less accurate with increasing time, restricting their use to calculating the memory kernel leads to an accurate description of the electronic dynamics. Comparison with a previously proposed procedure for calculating the memory kernel via the Ehrenfest method reveals that MH/LSC methods produce memory kernels that are better behaved at long times and lead to more accurate electronic dynamics.
Modeling of striplines between a power and a ground plane (2006)

In this paper, a stripline model is presented for coupled signal lines routed between a power and a ground plane based on multiconductor transmission line (MTL) theory. Through a suitable diagonalization of the MTL equations for striplines, the transverse electromagnetic (TEM) parallel-plate mode is decoupled from the stripline mode. In this way, stripline models that are obtained assuming ideal planes at ground potential can be extended to take into account the nonideal behavior of the planes. The presented model is applied to represent mode conversion due to vias, holes in the reference planes, and terminations of the stripline. Influence of inhomogeneous media is discussed.
Reductive Cross-Coupling of 3-Substituted Δ<sup>3</sup>-Cephems with Alkenyl Halides in an Al/PbBr<sub>2</sub>/NiBr<sub>2</sub>(bpy) Triplemetal Redox System. Synthesis of 3-Alkenyl-Δ<sup>3</sup>-cephems (2000)

Synthesis of 3-alkenyl-delta 3-cephems was performed successfully by cross-coupling 3-(trifluoromethylsulfonyloxy or chloro)-delta 3-cephem with alkenyl halides, e.g., vinyl bromide, trans-1-bromo-1-propene, and trans-beta-bromostyrene in an Al/cat.PbBr2/cat.NiBr2(bpy)/NMP (or DMF) system. Reduction of 3-(trifluoromethylsulfonyloxy)-delta 3-cephem into norcephalosporin was also achieved by a similar reaction in the presence of 5 molar equiv of water. Scope and a plausible mechanism of the Al/Pb/Ni triplemetal-redox promoted reactions are discussed.
Detection of Adsorbed Water and Hydroxyl on the Moon (2009)

Data from the Visual and Infrared Mapping Spectrometer (VIMS) on Cassini during its flyby of the Moon in 1999 show a broad absorption at 3 micrometers due to adsorbed water and near 2.8 micrometers attributed to hydroxyl in the sunlit surface on the Moon. The amounts of water indicated in the spectra depend on the type of mixing and the grain sizes in the rocks and soils but could be 10 to 1000 parts per million and locally higher. Water in the polar regions may be water that has migrated to the colder environments there. Trace hydroxyl is observed in the anorthositic highlands at lower latitudes.
Modification of human placental alkaline phosphatase by periodate-oxidized 1,<i>N</i>6-ethenoadenosine monophosphate (1990)

Oxidation of 1,N6-ethenoadenosine monophosphate (epsilon AMP) with periodate cleaved the cis-diol of the ribose ring and resulted in the formation of a dialdehyde derivative (epsilon AMP-dial). At room temperature epsilon AMP-dial was unstable and underwent beta-elimination to give 4',5'-anhydro-1,N6-ethenoadenosine dialdehyde acetal (A epsilon Ado-dial). These nucleotide analogues were found to inactivate human placental alkaline phosphatase in a time- and concentration-dependent manner. epsilon AMP-dial was shown to be an affinity label for the enzyme on the basis of the following criteria. (a) Kinetics of the enzyme activity loss over a wide range of epsilon AMP-dial concentration showed a saturating phenomenon. Removal of the phosphate group made the reagent (A epsilon Ado-dial) become a general chemical modifying reagent. (b) The artificial substrate p-nitrophenyl phosphate gave substantial protection of the enzyme against inactivation. (c) epsilon AMP-dial was a substrate and a partial mixed-type inhibitor for the enzyme. Results of the inhibition and protection studies indicated that the reagent and substrate could combine with the enzyme simultaneously. Besides the phosphate-binding domain, an induced hydrophobic region is proposed for the substrate-binding site for human placental alkaline phosphatase.