gebhart/patrepeval huggingface dataset:
Stuck-Pipe Prediction With Automated Real-Time Modeling and Data Analysis (2016)

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 178888, “Stuck-Pipe Prediction Using Automated Real-Time Modeling and Data Analysis,” by Kent Salminen, SPE, Curtis Cheatham, SPE, Mark Smith, SPE, and Khaydar Valiulin, SPE, Weatherford, prepared for the 2016 SPE/IADC Drilling Conference and Exhibition, Fort Worth, Texas, USA, 1–3 March. The paper has not been peer reviewed. A real-time method is presented to predict impending stuck pipe with sufficient warning to prevent it. The new method uses automated analysis of real-time modeling coupled with real-time- data analysis. It can be applied to all well types for any well operation. The new method combines two types of analysis: (1) deviation of real-time data from real-time model predictions by use of hydraulics and torque-and-drag software, and (2) trend analysis of real-time data. Data Types and Frequency The approach taken was to first study real-time data sets from wells in which stuck-pipe incidents occurred and determine the root cause of each. The majority of these wells were drilled between 2009 and 2013 in the Eagle Ford shale. Specific patterns in the data were then identified as potential leading indicators of stuck pipe. One of the first issues identified was that the type, frequency, and quality of data available are not consistent from well to well. To ensure that the alerting system was configured to work on different well types with a high degree of functionality, the decision was made that it would be designed to monitor a well and provide alerts even if only “critical” data streams are available. These critical streams would meet the following criteria: Available on most rigs capable of capturing real-time data Be useful in determining information about the drillstring, drilling fluid, and the wellbore itself Fit within a logical progression that can indicate impending stuck pipe
Image reconstruction from minimum helical cone-beam projections (2004)

We proposed a new reconstruction algorithm for image reconstruction from helical cone-beam data only within the Tam-Danielsson window, thus allowing the potential reduction of radiation dose to patients. The new algorithm can be expressed as two terms. The first term dominates the contribution to the reconstructed image, and the second term provides only a small correction. In fact, such a correction is generally negligible as compared to that from the first term and introduces a detectable DC-type shift to the reconstructed images only in the situations where the ratio between the size of field of view and the helical radius approaches to 0.625, which is the limit to the validity of the first term. Based on the Grangeat formula, we have developed an algorithm to calculate the correction (i.e., the second) term from the data within the window.
Molecular insights into substrate specificity of prostate specific antigen through structural modeling (2009)

Prostate Specific Antigen's (PSA) role as a biomarker for prostate cancer is well established but the physiological role of its serine protease activity in the pathobiology of normal prostate and prostate carcinogenesis remains largely unknown. In light of recent studies that implicate PSA's enzymatic activity in the initiation and/or progression of prostate cancer, we performed a molecular modeling study of substrate binding at the catalytic site of PSA wherein a PSA-selective substrate (HSSKLQ) was docked in an acyl-enzyme conformation to a three-dimensional homology model of PSA. Additionally, virtual positional scanning studies were conducted to gain mechanistic insights into substrate recognition of PSA. Subsequently, 13 novel peptide substrates of 6-aa length and four peptide substrates with varying length were synthesized and assayed for PSA hydrolysis to evaluate the experimental validity of docking insights. Additionally, six novel aldehyde-containing transition state analog inhibitors were synthesized and tested for their inhibitory potencies. The experimental data on the hydrolysis rates of the newly synthesized substrates and inhibitory potencies of the aldehyde peptides agreed with the docking predictions, providing validation of the docking methodology and demonstrating its utility towards the design of substrate-mimetic inhibitors that can be used to explore PSA's role in the pathobiology of prostate cancer.
Control of the cell-specificity of σF activity in <i>Bacillus subtilis</i> (1996)

Sporulation in Bacillus subtilis is a simple developmental system involving the differentiation of two cell types that are formed by an asymmetric cell division. Major changes in the pattern of transcription during sporulation are brought about by the synthesis of new sigma factors (sigma), which are subunits of RNA polymerase that determine promoter specificity. Transcription in the smaller prespore cell type is initiated by a sigma factor called sigma F, the activity of which is subject to tight spatial and temporal control. It is negatively regulated by an anti-sigma factor, SpoIIAB, which is in turn controlled by an anti-anti-sigma factor, SpoIIAA. SpoIIAA and SpoIIAB participate in two contrasting reactions in vitro. In the presence of ATP, the proteins interact transiently and SpoIIAA is inactivated by phosphorylation on a specific serine residue; SpoIIAA then remains free to inhibit sigma F. In the presence of ADP, SpoIIAA binds tightly to SpoIIAB, and sigma F is set free. Release of sigma F activity in vivo might thus be effected by a prespore-specific reduction in the ATP/ADP ratio. Genetic experiments have implicated a fourth protein, called SpoIIE, in this system. It now appears that SpoIIE has two important and independent functions in the establishment of the prespore-specific transcription by sigma F. First it regulates sigma F activity, probably acting as a phosphatase to regenerate the active, non-phosphorylated form of SpoIIAA. Second it controls the formation of the septum that generates the prespore compartment. Combination of these two functions in a single polypeptide may provide a means of coupling gene expression with morphogenesis.
Stability of Inviscid Plane Couette Flow (1960)

The initial-value problem corresponding to a perturbed inviscid plane Couette flow is solved. Difficulties encountered in applying classical hydrodynamic-stability methods are avoided by considering the initial value problem.
The MATE workbench: a tool for annotating XML corpora (2000)

This paper describes the design and implementation of the MATE workbench, a program which provides support for flexible display and editing of XML annotations, and complex querying of a set of linked files. The workbench was designed to support the annotation of XML coded linguistic corpora, but it could be used to annotate any kind of data, as it is not dependent on any particular annotation scheme. Rather than being a general purpose XMLaware editor it is a system for writing specialised editors tailored to a particular annotation task. A particular editor is defined using a transformation language, with suitable display formats and allowable editing operations. The workbench is written in Java, which means that it is platform-independent. This paper outlines the design of the workbench software and compares it with other annotation programs. 1. Introduction The annotation or markup of files with linguistic or other complex information usually requires either human coding or human ...
Dimerization through the helix-loop-helix motif enhances phosphorylation of the transcription activation domains of myogenin. (1994)

The muscle-specific basic helix-loop-helix (bHLH) protein myogenin activates muscle transcription by binding to target sequences in muscle-specific promoters and enhancers as a heterodimer with ubiquitous bHLH proteins, such as the E2A gene products E12 and E47. We show that dimerization with E2A products potentiates phosphorylation of myogenin at sites within its amino- and carboxyl-terminal transcription activation domains. Phosphorylation of myogenin at these sites was mediated by the bHLH region of E2A products and was dependent on dimerization but not on DNA binding. Mutations of the dimerization-dependent phosphorylation sites resulted in enhanced transcriptional activity of myogenin, suggesting that their phosphorylation diminishes myogenin's transcriptional activity. The ability of E2A products to potentiate myogenin phosphorylation suggests that dimerization induces a conformational change in myogenin that unmasks otherwise cryptic phosphorylation sites or that E2A proteins recruit a kinase for which myogenin is a substrate. That phosphorylation of these dimerization-dependent sites diminished myogenin's transcriptional activity suggests that these sites are targets for a kinase that interferes with muscle-specific gene expression.
Restoration of out-of-focus images based on circle of confusion estimate (2002)

In this paper a new method for a fast out-of-focus blur estimation and restoration is proposed. It is suitable for CFA (Color Filter Array) images acquired by typical CCD/CMOS sensor. The method is based on the analysis of a single image and consists of two steps: 1) out-of-focus blur estimation via Bayer pattern analysis; 2) image restoration. Blur estimation is based on a block-wise edge detection technique. This edge detection is carried out on the green pixels of the CFA sensor image also called Bayer pattern. Once the blur level has been estimated the image is restored through the application of a new inverse filtering technique. This algorithm gives sharp images reducing ringing and crisping artifact, involving wider region of frequency. Experimental results show the effectiveness of the method, both in subjective and numerical way, by comparison with other techniques found in literature.
Two-dimensional waveform analysis in MR elastography of skeletal muscles (2005)

A method for direct determination of anisotropic elastic coefficients using two-dimensional shear wave patterns is introduced. Thereby, the symmetry of the wave patterns is approximated by a squared elliptic equation yielding an explicit relation between waveform and elasticity. The method is used to analyse MR elastography wave images of the biceps acquired by a continuous harmonic excitation at the distal tendon of the muscle. Typically V-shaped wave patterns were observed in this type of tissue, which could be well reproduced by the proposed elliptic approximation of the waveform assuming incompressibility and a transverse isotropic model of elasticity. Without additional experiments, the analysis of straightness, slope and interferences of the wave fronts enabled us to deduce two Young's moduli and one shear modulus, which fully describe the anisotropy of the elasticity of muscles. The results suggest strong anisotropy of the living human biceps causing a shear wave speed parallel to the muscle fibres that is approximately four times faster than the perpendicular shear wave speed.
Inhibition of bacteria on agar surfaces by vapour phase triclosan (2003)

Sir, Triclosan is the most widely used member of the bisphenol family of disinfectants, which are characterized by their high intrinsic activities and proportional low solubility in water. Unfortunately, they also share ineffectiveness against pseudomonads and an ability to select for resistance in Staphylococcus aureus. In recent years, an increasing number of domestic plastic and cleaning products incorporating triclosan have been marketed under the Microban trade mark. In their paper in this journal 1 on triclosan-impregnated food-storage boxes, Braid & Wale described, but were “unable to account for the complete suppression of growth of S. aureus on one side of open agar plates that were directly adjacent to the triclosan-impregnated wall of the 9 L boxes used”. This effect is reproducible and we have also demonstrated it, under experimental conditions, by exposure of strains of both S. aureus and Escherichia coli to a proprietary Microban household cleaning fluid and a 5% solution of triclosan. The degree of inhibition appears to be proportional to both the concentration of the agent and the respective susceptibility of the test strains. The authors 1 also found it difficult to equate the vapour phase of triclosan with the pattern of inhibition found, asking why all of their plates had not been affected equally and evenly; however, we believe that the pattern of suppression seen can be entirely explained in terms of classical zone formation theory.2 In our experiments, we inoculated nutrient agar plates with our test organisms, as if for a conventional susceptibility test. We then aseptically removed one-third of the agar and, into the space, we placed an inverted plastic cap from a 5 mL bottle, filled with either the Microban cleaning fluid or 5% triclosan. The plates, with lids, were incubated overnight at 37°C and examined for inhibition. Large, rather flattened, zones of inhibition were seen immediately opposite the reservoir of cleaning fluid. We also used modified Petri dishes, in which spacing shims held the inoculated agar surfaces at varying heights above reservoirs of the test solutions. Large zones of inhibition were formed at heights of up to 6 cm. It was noted that the label on the cleaning fluid bottle stated that the product also contained formaldehyde. However, tests indicated that the inhibition zones produced were consistent with those produced by triclosan and the differences in zone sizes seen between the test strains were consistent with the differing MICs of triclosan for those organisms.
A linear-time heuristic for improving network partitions (1988)

Article A linear-time heuristic for improving network partitions Share on Authors: C. M. Fiduccia General Electric, Research and Development Center, Schenectady, NY General Electric, Research and Development Center, Schenectady, NYView Profile , R. M. Mattheyses General Electric, Research and Development Center, Schenectady, NY General Electric, Research and Development Center, Schenectady, NYView Profile Authors Info & Claims 25 years of DAC: Papers on Twenty-five years of electronic design automationJune 1988 Pages 241–247https://doi.org/10.1145/62882.62910Published:01 June 1988 64citation939DownloadsMetricsTotal Citations64Total Downloads939Last 12 Months30Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
MAÑANA SE PROYECTARÁ RITO TERMINAL EN VARIAS SALAS DE CINE EN LA CIUDAD DE MÉXICO (2000)

RITO TERMINAL, PRIMER LARGOMETRAJE DEL PROGRAMA OPERA PRIMA DE EGRESADOS DEL CENTRO UNIVERSITARIO DE ESTUDIOS CINEMATOGRAFICOS (CUEC), QUE MANANA INICIA SU DISTRIBUCION PROYECTANDOSE EN VARIAS SALAS SELECTAS DE LA CIUDAD DE MEXICO, ES UN FILME QUE CUMPLE CON CRECES LAS METAS DE DICHO PROGRAMA, RESULTADO DE UN CONVENIO ESTABLECIDO ENTRE LA UNAM Y EL INSTITUTO MEXICANO DE CINEMATOGRAFIA (IMCINE). UNA VEZ MAS LA UNIVERSIDAD NACIONAL IMPULSA UNA INICIATIVA CON OBJETIVOS CLARAMENTE ACADEMICOS QUE FAVORECEN A SUS ALUMNOS. EL DEBUT PROFESIONAL DE LAS RECIENTES GENERACIONES DE EGRESADOS YA COMENZO Y CON BUENOS AUGURIOS. CON LA OPERA PRIMA DE OSCAR URRUTIA, COMO PRIMERA EXPERIENCIA DEL PROGRAMA, MITL VALDEZ, DIRECTOR DEL CUEC, EXPLICO QUE SE CONCRETA EL OBJETIVO DE REALIZAR UN FILME INNOVADOR BASADO EN UN TEMA QUE EMANA DE NUESTRA REALIDAD CULTURAL, Y QUE CON UNA ESTRUCTURA NARRATIVA ATRACTIVA BUSCA LA REVALORIZACION DE LA TRADICION CINEMATOGRAFICA MEXICANA Y SU RIQUEZA. VALDEZ, JUNTO CON IGNACIO SOLARES, COORDINADOR DE DIFUSION CULTURAL; IVAN TRUJILLO, DIRECTOR GENERAL DE ACTIVIDADES CINEMATOGRAFICAS, Y EL EQUIPO CREATIVO, DEL ELENCO Y DEL GRUPO DE INTERPRETES DE LA MUSICA ORIGINAL DE LA PELICULA, ASISTIERON A LA PREMIER DE ESTA Y LA PRESENTACION DEL DISCO COMPACTO.
Outperforming the Conventional Scaling Rules in the Quantum-Capacitance Limit (2008)

We present a study on the scaling behavior of field- effect transistors in the quantum-capacitance limit (QCL). It will be shown that a significant performance improvement in terms of the power delay product can be obtained in devices scaled toward the QCL. As a result, nanowires or nanotubes exhibiting a 1-D transport are a premier choice as active channel materials for transistor devices since the QCL can be attained in such systems.
A regulatory role for the CD4 and CD8 molecules in T cell activation. (1988)

The role of the CD4 and CD8 molecules in T cell activation is presently a matter of controversy. Although their role as associative binding elements to MHC class II or class I is well documented, their influence on the triggering process in unclear. Because antibodies to CD4 or CD8 block T cell activation in the absence of their respective ligands, a negative signaling by these molecules has been suggested. However, recent experimental evidence argues against a negative regulatory effect of these molecules, since, e.g., simultaneous cross-linking of TCR and CD4 leads to enhanced T cell activation. Therefore, a current model suggests that the association of TCR and CD4 in the membrane gives a positive signal essential for triggering. In this report we present evidence that this model is likely to be too simple. Anti-CD4 and CD8 antibodies inhibit alternative, nonreceptor pathways of T cell triggering via Tp103 and Tp44 in the absence of class II positive accessory or target cells. These antibodies also inhibit bypass activation of T cells by phorbol ester and calcium ionophore in an accessory cell-free system. Furthermore, if the CD4 or CD8 molecules are removed from the cell surface by antibody-induced modulation, the proliferative and cytotoxic response of T cell clones is enhanced. This enhancement is also observed if resting peripheral blood T cells are used as responder cells. These data show that the CD4 or CD8 molecules have a complex regulatory function in T cell activation beyond the requirement for co-cross-linking with the TCR.
<title>Improved resolution of submicron KrF laser ablation of polymers by a new filtered imaging irradiation</title> (2004)

Surface grating-like ablation with microscopic period (Λ ~ 1-5 μm) is achieved at the surface of polymers with the aid of the KrF laser patterned with a mask projection technique using a precision imaging lens. The ablated patterns can be controlled with a submicron accuracy in most cases on smooth polymer surfaces. Prediction of these patterns can furthermore be made with the aid of theoretical models combining ablation curves, intensity profiles and hydrodynamic flow. We further demonstrate that by using harmonic filtering the grating period can be divided by a factor 2 thus leading to a convenient resolution enhancement. This improvement can be achieved by two experimental approaches. One is by changing the defocus and the other is the removal of low level orders (0 and ± 1) of the Fourier components of the image beams. Resulting grating patterns with doubled spatial frequency will be presented for a number of polymeric materials (AFM, SEM). It reveals to be a good method to overcome the theoretical limitations due to numerical aperture of the precision lens which prevent the transfer of details in the image by erasing the high spatial frequencies. This interesting optical set up and method offer also the advantage of a large working distance above the sample surface which is compatible with irradiations in vacuum and liquid phase.
Combined DCE‐MRI and single‐voxel 2D MRS for differentiation between benign and malignant breast lesions (2010)

Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and proton (1H) magnetic resonance spectroscopy (MRS) provide structural and biochemical information, including vascular volume, vascular permeability and tissue metabolism. In this study, we performed analysis of the enhancement characteristic from DCE-MRI and the biochemical information provided by two-dimensional (2D) Localized Correlated Spectroscopy (L-COSY) MRS to determine the sensitivity and specificity of using DCE-MRI alone compared to the combination with 2D MRS. The metabolite ratios from the 2D MRS spectra were analyzed using multivariate statistical analyses to determine a method capable of automatic separation of the patient cohort into malignant and benign lesions. A total of 24 lesions were studied with 21 diagnosed accurately using the enhancement characteristics alone resulting in sensitivity and specificity of 100% and 73%, respectively. Analysis of the 2D MRS data demonstrated a significant difference (p < 0.05) in 12 of 18 metabolite ratios analyzed for malignant compared to benign lesions. Previous research focused on utilizing the choline signal to noise ratio (SNR) as a marker for malignancy has been verified using 2D MRS in this study. Using Fisher's linear discriminant test using water (WAT)/olefinic fat diagonal (UFD), choline (CHO)/fat (FAT), CHO/UFD, and FAT/methyl fat (FMETD) as predictors the sensitivity and specificity increased to 92% and 100%, respectively. Using the Classification and Regression Tree (CART) statistical analysis the resulting sensitivity and specificity were 100% and 91%, respectively, with the most accurate predictor for differentiating malignant and benign determined to be FAT/FMETD. The cases within the study that presented a indeterminate diagnosis using DCE-MRI alone were able to be accurately diagnosed when the metabolic information from 2D MRS was incorporated. The results suggest improved breast cancer detection through the combination of morphological and enhancement information from DCE-MRI and metabolic information from 2D MRS.
Fabrication and performance evaluation of hybrid supercapacitor electrodes based on carbon nanotubes and sputtered TiO<sub>2</sub> (2016)

We report a simple and eco-friendly method for the fabrication of a titanium dioxide/functionalized multiwalled carbon nanotube (TiO2/FMWCNT) composite electrode for use in supercapacitors. The nanocomposite electrodes were formed by depositing titanium dioxide onto FMWCNTs using reactive magnetron sputtering, thus providing a green roue for the formation of the binder-free composite electrode. It is shown that the electrochemical performance of the fabricated electrodes can be altered by tuning the thickness of the titanium dioxide overlayer. The integrated nanocomposite electrode showed an improved specific capacitance of 90 Fg(-1) in two-electrode configuration.
Fabrication and optical characterization of high-density Al2O3 doped with slight MnO dopant (2008)

Effects of manganese oxide (MnO) addition on the densification of Al2O3 during sintering were studied. Although MnO is commonly used as a sintering aid for Al2O3, it has not been used as a sintering aid to produce transparent alumina. High-density Al2O3 doped with slight MnO (> 99.5%) was obtained using a conventional powder processing method, with sintering at 1250°C for 24 h. The Al2O3- 0.05 mass%MnO exhibited optical total transmittance of 42% at 600 nm wavelength and three-point bending strength of 528 MPa. The transmittance was further improved to greater than 70% at 600 nm through hot isostatic pressing (HIP) after conventional sintering. The possibility of high-strength transparent alumina was demonstrated.