gebhart/patrepeval huggingface dataset:
Robust speech coding using microphone arrays (2002)

The paper describes a robust speech coder that uses a microphone array. The array processor functions as a noise canceller and a voice activity detector, thus giving the coder improved speech quality and lowered bit rates even in extremely noisy conditions (SNR<0 dB). Preliminary results have shown the effectiveness of the scheme under several noisy and reverberant room environments.
Cloning and Characterization of a Nonhemolytic Phospholipase C Gene from <i>Burkholderia pseudomallei</i> (1999)

We cloned and characterized a phosphatidylcholine-hydrolyzing phospholipase C (PC-PLC) gene from Burkholderia pseudomallei. DNA sequence analysis of the gene indicated an open reading frame coding for 700 amino acids with a 34-amino-acid signal peptide. When cleaved, this yields a secreted 73-kDa mature protein. The deduced amino acid sequence exhibited 48% similarity to that of a nonhemolytic PLC from Pseudomonas aeruginosa. The expressed PC-PLC was heat stable, nonhemolytic for sheep erythrocytes, and active between pH 2 and 8. Western blot analysis with sera from melioidosis patients indicated that they produced immunoglobulin M antibodies against this PC-PLC protein.
In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against <i>Cryptosporidium parvum</i> (1996)

The anticryptosporidial activity of four macrolides alone and in combination with other antimicrobial agents was investigated against ten clinical isolates of Cryptosporidium parvum recovered from stools of AIDS patients. The susceptibility tests were performed by inoculation of the protozoa on to cell monolayers and determining the parasite count after 72 h incubation at 37 degrees C. The culture medium was supplemented with Dulbecco's modified Eagle's medium containing serial dilutions of azithromycin, clarithromycin, roxithromycin, spiramycin, alone or in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine. Most of the agents had an inhibitory effect on parasite growth, but only at high concentrations. No agent was able to inhibit parasite growth completely, even at the highest concentrations used. The more effective agents, azithromycin, clarithromycin, roxithromycin, minocycline and pyrimethamine, produced no more than a 13.1-27.8% reduction in oocyst count and no more than a 15.1-35.7% in schizont count. Positive interaction was clearly demonstrated when macrolides were tested in combination with minocycline or pyrimethamine.
Susceptibilidad in vitro de cepas de Helicobacter pylori: aislamiento de cepas resistentes a claritromicina (2001)

These results underscore the need to maintain an epidemiological surveillance of H pylori antimicrobial susceptibility, to modify its eradication therapy accordingly.
Changes of Surface Properties and Water-Tolerant Catalytic Activity of Solid Acid Cs<sub>2.5</sub>H<sub>0.5</sub>PW<sub>12</sub>O<sub>40</sub>in Water (1998)

Cs2.5H0.5PW12O40, a hydrogen cesium salt of dodecatungstophosphoric acid, exhibited a high catalytic activity for hydrolysis of ethyl acetate in large excess water. Adsorption of water demonstrated that interactions between Cs2.5H0.5PW12O40 and water are weak. This nature and the strong acidity are possible reasons for the high activity. Changes of the catalytic performance, acidic property, and pore structure of Cs2.5H0.5PW12O40 by heat treatments in water were investigated. The decrease in the activity by the treatments was small at 353 K but was appreciable at 393 K. The calorimetry of ammonia adsorption showed that the water treatments reduced the acid amount, whereas the acid strength was little changed, indicating that the decrease in the catalytic activity was due to that in the acid amount. Pore size distribution analysis of Cs2.5H0.5PW12O40 with nitrogen adsorption revealed that the pore became larger by the water treatment. Infrared spectroscopy confirmed that the primary structure (Keggin structure) of the heteropoly compound was retained in hot water. A small amount of heteropoly species was released into water during the treatments, which was detected by UV spectroscopy. It was concluded that the released species were not ionically dissociated but present as heteropoly clusters. The changes of the pore structure are discussed in relation to alteration of the aggregated state of Cs2.5H0.5PW12O40 crystallites.
Glycosylation Catalyzed by a Chiral Brønsted Acid (2010)

The use of a chiral Brønsted acid catalyst for the activation of trichloroacetimidate glycosyl donors has been demonstrated for the first time. In toluene the chirality of the acid catalyst is seen to influence the stereochemical outcome of the glycosylation processes, hinting that perhaps diastereocontrol of glycosylation processes may become achievable through the judicious use of chiral organic catalysts.
Involvement of heme biosynthesis in control of sterol uptake by Saccharomyces cerevisiae (1985)

Wild-type Saccharomyces cerevisiae do not accumulate exogenous sterols under aerobic conditions, and a mutant allele conferring sterol auxotrophy (erg7) could be isolated only in strains with a heme deficiency. delta-Aminolevulinic acid (ALA) fed to a hem1 (ALA synthetase-) erg7 (2,3-oxidosqualene cyclase-) sterol-auxotrophic strain of S. cerevisiae inhibited sterol uptake, and growth was negatively affected when intracellular sterol was depleted. The inhibition of sterol uptake (and growth of sterol auxotrophs) by ALA was dependent on the ability to synthesize heme from ALA. A procedure was developed which allowed selection of strains which would take up exogenous sterols but had no apparent defect in heme or ergosterol biosynthesis. One of these sterol uptake control mutants possessed an allele which allowed phenotypic expression of sterol auxotrophy in a heme-competent background.
Efficient Data Access Algorithms for ITS-based Networks with Multi-Hop Wireless Links (2007)

In this paper, we investigate efficient data access algorithms in intelligent transportation system (ITS)-based networks with multi-hop wireless links. We introduce a proxy cache (PC) and propose PC-based poll-each-read (P-PER) and PC-based callback (P-CB) data access algorithms to reduce the transmission cost over the bottleneck wireless links. Extensive simulation results are given to demonstrate the performance of P-PER and P-CB. It is shown that P-PER and P-CB can improve the cache hit performance and reduce the transmission cost significantly. A tradeoff between P-PER and P-CB suggests the need to use a hybrid proxy-based approach to attain optimal performance of data access in ITS-based networks with multi-hop wireless links.
Nucleophilic vinylic substitution approach to derivatives of fulvic acid (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNucleophilic vinylic substitution approach to derivatives of fulvic acidOsmo E. O. Hormi and A. Marikka PaakkanenCite this: J. Org. Chem. 1987, 52, 23, 5275–5276Publication Date (Print):November 1, 1987Publication History Published online1 May 2002Published inissue 1 November 1987https://pubs.acs.org/doi/10.1021/jo00232a040https://doi.org/10.1021/jo00232a040research-articleACS PublicationsRequest reuse permissionsArticle Views183Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Conditional Value-at-Risk and Average Value-at-Risk: Estimation and Asymptotics (2012)

We discuss linear regression approaches to the estimation of law-invariant conditional risk measures. Two estimation procedures are considered and compared; one is based on residual analysis of the standard least-squares method, and the other is in the spirit of the M-estimation approach used in robust statistics. In particular, value-at-risk and average value-at-risk measures are discussed in detail. Large sample statistical inference of the estimators is derived. Furthermore, finite sample properties of the proposed estimators are investigated and compared with theoretical derivations in an extensive Monte Carlo study. Empirical results on the real data (different financial asset classes) are also provided to illustrate the performance of the estimators.
Nonlinear Multi-Error Correction Codes for Reliable MLC nand Flash Memories (2011)

Multi-level cell (MLC) nand flash memories are popular storage media because of their power efficiency and large storage density. Conventional reliable MLC nand flash memories based on BCH codes or Reed-Solomon (RS) codes have a large number of undetectable and miscorrected errors. Moreover, standard decoders for BCH and RS codes cannot be easily modified to correct errors beyond their error correcting capability <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</i> =[( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</i> -1/2)], where <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</i> is the Hamming distance of the code. In this paper, we propose two general constructions of nonlinear multi-error correcting codes based on concatenations or generalized from Vasil'ev codes. The proposed constructions can generate nonlinear bit-error correcting or digit-error correcting codes with very few or even no errors undetected or miscorrected for all codewords. Moreover, codes generated by the generalized Vasil'ev construction can correct some errors with multiplicities larger than <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</i> without any extra overhead in area, latency, and power consumption compared to schemes where only errors with multiplicity up to <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</i> are corrected. The design of reliable MLC nand flash architectures can be based on the proposed nonlinear multi-error correcting codes. The reliability, area overhead and the penalty in latency and power consumption of the architectures based on the proposed codes are compared to architectures based on BCH codes and RS codes. The results show that using the proposed nonlinear error correcting codes for the protection of MLC nand flash memories can reduce the number of errors undetected or miscorrected for all codewords to be almost 0 at the cost of less than 20% increase in power and area compared to architectures based on BCH codes and RS codes.
Increased microRNA-34c abundance in Alzheimer's disease circulating blood plasma (2014)

Circulating microRNAs, present either in the cellular component, peripheral blood mononuclear cells (PBMC), or in cell-free plasma, have emerged as biomarkers for age-dependent systemic, disease-associated changes in many organs. Previously, we have shown that microRNA (miR)-34a is increased in circulating PBMC of Alzheimer's disease (AD) patients. In the present study, we show that this microRNA's sister, miR-34c, exhibits even greater increase in both cellular and plasma components of AD circulating blood samples, compared to normal age-matched controls. Statistical analysis shows the accuracy of levels of miR-34c assayed by receiver operating characteristic (ROC) analysis: the area under the curve is 0.99 (p < 0.0001) and the 95% confidence level extends from 0.97 to 1. Pearson correlation between miR-34c levels and mild and moderate AD, as defined by the mini-mental state examination (MMSE), shows an r-value of -0.7, suggesting a relatively strong inverse relationship between the two parameters. These data show that plasma levels of microRNA 34c are much more prominent in AD than those of its sister, miR-34a, or than its own level in PBMC. Transfection studies show that miR-34c, as does its sister miR-34a, represses the expression of several selected genes involved in cell survival and oxidative defense pathways, such as Bcl2, SIRT1, and others, in cultured cells. Taken together, our results indicate that increased levels of miR-34c in both PBMC and plasma may reflect changes in circulating blood samples in AD patients, compared to age-matched normal controls.
Design and implementation of DCAS user terminal (2011)

This paper presents an efficient design and implementation of user terminal for Downloadable Conditional Access System (DCAS). The DCAS system enables cable operators to flexibly change and update their Conditional Access Systems (CAS) without hardware changes by downloading CA applications through Hybrid Fiber Coaxial (HFC) network. In order to do this, the DCAS user terminal provides DCAS functionalities including CA client download and update through DCAS protocol. The proposed design and implementation in this paper can be used to develop advanced DCAS user devices such as smart phone supporting broadcasting and communication converged services.
Peter De La Roche (1893)

Peter De La Roche Get access Petros Petros Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s8-IV, Issue 84, 5 August 1893, Page 108, https://doi.org/10.1093/nq/s8-IV.84.108c Published: 05 August 1893
Membrane Biocompatibility Does Not Affect Whole Body Protein Metabolism during Dialysis (2005)

In stable hemodialysis patients with no apparent complications, protein metabolism during dialysis is not affected by the compatibility of the dialysis membrane.
Synthesis of PbTe‐SnTe particles by thermal decomposition of salts to create nano‐structured thermoelectric materials (2012)

Abstract Micro‐ and nanocrystalline particles of Pb‐Sn‐Te mixed crystals were synthesized using thermal decomposition and chemical interaction of lead acetate, tin oxalate and tellurium powder mixture in H 2 atmosphere. For the process parameter optimization data of thermal gravimetry (TG), X‐ray diffraction (XRD), electronic microscopy (TEM, SEM) and measurements of the specific surface of particles were used. Additionally the influence of gas phases on the decomposition kinetics, crystal structure, size, specific surface of the particles, gains composition and the physical properties were analyzed. Seebeck coefficient values increased and conductivity decreased with decreasing tin concentration. The presented method for preparing PbTe‐SnTe polydisperse particles is developed to create nano‐structured thermoelectric materials with high figure of merit. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Improving mechanical stiffness of coated benzocyclobutene (BCB) based neural implant (2005)

We briefly report recent results of a simple alternate method to improve mechanical stiffness of BCB polymer neural implant for surgical insertion into brain tissue, which uses coatings dissolvable in bio-fluids. We have studied three different coating materials such as thermo-reversible gel Poloxamer 407, glucose (C6H12O6) and regular table sugar that were applied by dip coating onto the implant surface. The preliminary results of this study have shown that coating BCB probes with Poloxamer 407 polymer, a thermo-reversible gel, or table sugar significantly improves the buckling strength. However, the table sugar coating provides the greatest increase in stiffness, which is sufficient to penetrate both the preserved and live brain tissues without buckling.
Labeling of Dietary Supplements (2005)

Abstract The Dietary Supplement Health and Education Act (DSHEA 1994) provides for the use of label statements on dietary supplements. In the “Dietary Supplement Strategy: The Ten Year Plan” (Jan. 2000) and “Better Health Information for Consumers Initiative” (Dec. 2002), the FDA placed emphasis on improving consumer labeling information and strengthening enforcement of DSHEA rules. The purpose of this research project was to (1) gain insight into consumer's awareness and understanding of nutritional claims on dietary supplements using focus groups and (2) evaluate industry's compliance with selected labeling requirements by conducting product surveillance at retail establishments. Thirty-four individuals (17 men and 17 women) participated in the focus groups. Slightly more women (88%) than men (76%) indicated that they were familiar with nutritional claims on dietary supplements. While most consumers remain skeptical about the efficacy of dietary supplements and truthfulness of corresponding labeling, it does not preclude their use. The use of a scientific ranking system, similar to what's proposed for qualified health claims, for structural/function claims would provide a standard for claim substantiation and for consumers to judge their credibility. Five hundred thirty-five supplement products, manufactured and/or distributed by 238 companies, were evaluated for their compliance to selected labeling requirements. The majority (83%) of products screened, had labeling consistent with recent regulations. Having no or incomplete disclaimer with a structural/functional claim was the most common issue, occurring in 65% of the noncompliant products. The proportion of compliant and noncompliant products was not significantly different between retail categories.
Perceived proficiency in minimally invasive surgery among senior OB/GYN residents. (2010)

Senior Ob/Gyn residents seem to feel more comfortable performing advanced laparoscopic procedures at graduation than they did 7 years ago. The majority feels that the emphasis on training in minimally invasive surgery should be increased.
Agile Data Warehouse Design: Collaborative Dimensional Modeling, from Whiteboard to Star Schema (2011)

Agile Data Warehouse Design is a step-by-step guide for capturing data warehousing/business intelligence (DW/BI) requirements and turning them into high performance dimensional models in the most direct way: by modelstorming (data modeling + brainstorming) with BI stakeholders. Itdescribes BEAM, an agile approach to dimensional modeling, for improving communication between data warehouse designers, BI stakeholders and the whole DW/BI development team.BEAMprovides tools and techniques that will encourage DW/BI designers and developers to move away from their keyboards and entity relationship based tools and model interactively with their colleagues. The result is everyone thinks dimensionally from the outset! Developers understand how to efficiently implement dimensional modeling solutions. Business stakeholders feel ownership of the data warehouse they have created, and can already imagine how they will use it to answer their business questions. Topics include:Agile dimensional modeling using Business Event Analysis & Modeling (BEAM)Modelstorming: data modeling that is quicker, more inclusive, more productive, and frankly more fun!Telling dimensional data stories using the 7Ws (who, what, when, where, how many, why and how)Modeling by example,not abstraction; using data story themes, not crow's feet, to describe detailStoryboarding the data warehouse to discover conformed dimensions and plan iterative developmentVisual modeling: sketching timelines, charts and grids to model complex process measurement -simplyAgile design documentation: enhancing star schemas with BEAMdimensional shorthand notationSolving difficult DW/BI performance and usability problems with proven dimensional design patterns
Stem Cells Expressing Homing Receptors Could be Expanded From Cryopreserved and Unselected Cord Blood (2004)

We assessed the cytokine combinations that are best for ex vivo expansion of cord blood (CB) and the increment for cell numbers of nucleated cells, as well as stem cells expressing homing receptors, by an ex vivo expansion of cryopreserved and unselected CB. Frozen leukocyte concentrates (LC) from CB were thawed and cultured at a concentration of 110 5 /mL in media supplemented with a combination of SCF (20 ng/mL)+TPO (50 ng/mL)+FL (50 ng/mL)IL-6 (20 ng/mL)G-CSF (20 ng/mL). After culturing for 14 days, the expansion folds of cell numbers were as follows: TNC 22.37.8~26.34.9, CFU-GM 4.75.1~11.72.6, CD34+CD38-cell 214.0251.9~464.1566.1, CD34+CXCR4+ cell 4384.51664.7~7087.24669.3, CD34+VLA4+ cell 1444.31264.0~2074.91537.0, CD34+VLA5+ cell 86.250.91 13.257.1. These results revealed that the number of stem cells expressing homing receptors could be increased by an ex vivo expansion of cryopreserved and unselected CB using 3 cytokines (SCF, TPO, FL) only. Further in vivo studies regarding the engraftment after expansion of the nucleated cells, as well as the stem cells expressing homing receptors will be required.
Collective and molecular dynamics in low molar mass and polymeric ferroelectric liquid crystals (1993)

Abstract By use of a novel sample preparation technique, it is possible to measure with one sample cell the collective and molecular dynamics (10−1 Hz-109 Hz) of macroscopically (in bookshelf geometry) oriented ferroelectric liquid crystals. Below 106 Hz, two ferroelectric modes, Goldstone- and soft-mode, are observed, being assigned to fluctuations of the phase and amplitude of the helical superstructure respectively. Between 106 and 109 Hz, one dielectric loss process exists, the β-relaxation which originates from the librational motion (hindered rotation) of the mesogen around its molecular long axis. This process does not split or broaden at the non-ferroelectric-ferroelectric phase transition and it has an Arrhenius type temperature dependence. In comparing a racemic mixture with a chiral sample, it performs a similar frequency and temperature dependence. The experimental findings for the β-relaxation are in qualitative contrast to the predictions of the (generalized) Landau expansion of the free energy at the non-ferroelectric-ferroelectric phase transition. The experiment also leads to a modified understanding for the molecular origin of ferroelectricity in FLCs.
Cytotoxic activity and antiproliferative effects of a new semi-synthetic derivative of Ent-3 beta-hydroxy-13-epi-manoyl oxide on human leukemic cell lines. (2000)

Ent-3 beta-hydroxy-13-epi-manoyl oxide (1), was converted to its thiomidazolide derivative (2) which was tested for its cytotoxic activity against a panel of established human leukemic cell lines. Compound 2, exhibited cytotoxic activity against 13 of the cell lines tested. Additionally, compound 2 was examined for its effect on the uptake of [3H]-thymidine as a marker of DNA synthesis and on cell proliferation. The morphology of the cells and the kind of death induced, was investigated. Flow cytometry experiments on a leukemic cell line was also performed. The results show that the semi-synthetic compound, showed a significant antiproliferative effect and kills cells through the process of apoptosis. The appearance of the apoptotic signs was time and dose dependent. From the flow cytometry experiments, a synchronisation through a delay of the cells in G0/1, phase seems to take place.