gebhart/patrepeval huggingface dataset:
Circulating Vascular Endothelial Growth Factor in Patients With Colorectal Cancer (1998)

VEGF is involved in the development of colorectal cancer. Measurement of VEGF in the serum may be a useful noninvasive clinical marker for evaluating the disease status.
Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis (2016)

Chromatin-mediated processes influence the development and progression of breast cancer. Using murine mammary carcinoma-derived tumorspheres as a functional readout for an aggressive breast cancer phenotype, we performed a loss-of-function screen targeting 60 epigenetic regulators. We identified the Polycomb protein Cbx8 as a key regulator of mammary carcinoma both in vitro and in vivo. Accordingly, Cbx8 is overexpressed in human breast cancer and correlates with poor survival. Our genomic analyses revealed that Cbx8 positively regulates Notch signaling by maintaining H3K4me3 levels on Notch-network gene promoters. Ectopic expression of Notch1 partially rescues tumorsphere formation in Cbx8-depleted cells. We find that Cbx8 associates with non-PRC1 complexes containing the H3K4 methyltransferase complex component WDR5, which together regulate Notch gene expression. Thus, our study implicates a key non-canonical role for Cbx8 in promoting breast tumorigenesis.
Cl2‐Based Inductively Coupled Plasma Etching of NiFe and Related Materials (1998)

A parametric study of etch rates, surface quality, and mask materials for inductively coupled plasma (ICP) dry etched NiFe, NiFeCo, TaN, and CrSi in /Ar, , and chemistries is reported. The etch rates are a strong function of discharge composition, with maxima at ∼66% in each of the chemistries investigated, as are ion flux, ion energy, and pressure. The etch mechanism appears to be formation of chlorides that are desorbed by ion assistance. If the ion‐to‐neutral ratio is not optimized, then the etching reverts either to a pure sputtering regime or to net deposition through formation of a thick chlorinated selvedge layer on NiFe and NiFeCo.
Possibility of Creating a Common Currency Basket for East Asia (2003)

Proceedings of International Symposium on China's Economic Development and Structural Change in East Asia in Commemoration of the Foundation of Shanghai Center for Economic Research, Graduate School of Economics, Kyoto University. February 8 and 9, 2003, Shirankaikan, Kyoto.
Direct perfluoroalkylation of aromatic and heteroaromatic compounds with perfluoroalkanesulfonyl chlorides catalysed by a ruthenium(II) phosphine complex (1994)

The perfluoroalkylation of aromatic and heteroaromatic compounds by perfluoroalkanesulfonyl chlorides 1 has been investigated in the presence of a ruthenium(II) phosphine complex. The reaction of compounds 1 with substituted benzenes or thiophenes proceeded smoothly with extrusion of sulfur dioxide at 120 °C to give corresponding perfluoroalkylated compounds in good yield. No expected perfluoroalkylated product was obtained in the reaction of compounds 1 with pyrrole; however, 1-trimethylsilyl- and 1-triisopropylsilyl-pyrrole were regioselectively perfluoroalkylated at their 2- and 3-position, respectively.
Efficient hardware for multiway jumps and pre-fetches (1985)

article Free Access Share on Efficient hardware for multiway jumps and pre-fetches Authors: K. Karplus Department of Computer Science, Cornell University, Ithaca, NY Department of Computer Science, Cornell University, Ithaca, NYView Profile , A. Nicolau Department of Computer Science, Cornell University, Ithaca, NY Department of Computer Science, Cornell University, Ithaca, NYView Profile Authors Info & Claims ACM SIGMICRO NewsletterVolume 16Issue 4Dec. 1985 pp 11–18https://doi.org/10.1145/18906.18908Published:01 December 1985Publication History 15citation203DownloadsMetricsTotal Citations15Total Downloads203Last 12 Months13Last 6 weeks6 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Narrow-linewidth megahertz-repetition-rate optical parametric oscillator for high-speed flow and combustion diagnostics (2007)

We demonstrate the ability to generate ultra-high-frequency sequences of broadly wavelength-tunable, high-intensity laser pulses using a custom-built optical parametric oscillator pumped by the third-harmonic output of a "burst-mode" Nd:YAG laser. Burst sequences consisting of 6-10 pulses separated in time by 6-10 mus are obtained, with average total conversion efficiency from the 355 nm pump to the near-IR signal and idler wavelengths of approximately 33%. Typical individual pulse output energy for the signal and idler beams is in the range of 4-6 mJ, limited by the available pump energy. Line narrowing is demonstrated by means of injection seeding the idler wave using a low-power external-cavity diode laser at 827 nm. It is shown that seeding reduces the time-averaged linewidth of both the signal and idler outputs to approximately 300 MHz, which is near the 220 MHz Fourier transform limit. Line narrowing is achieved without recourse to active cavity stabilization.
Control of Noctuid Larvae on Cranberry, 1985 (1986)

Abstract The test was conducted on a 13-year-old section of State Bog in East Wareham, MA. Five treatments were replicated 4 times in randomized blocks composed of 5 × 5-ft plots separated by 2-ft pathways. Applications were made on 24 May at bud swell using a 2-gal, polyethylene compressed air sprayer. All treatments were diluted to the rate of 400 gal of water per acre to approximate conditions achieved commercially with overhead sprinkler systems. After the foliage dried, randomly selected vine uprights in each plot were pruned, placed in plastic bags in a cooler, and brought to the laboratory. Thirty undamaged uprights per plot were inserted into moistened sand within 2, ventilated, 8-oz styrofoam cups. Eleven h post-treatment, 12 field-collected larvae ranging in length from 0.5 to 0.75 in were introduced into each pair of cups. Cups were held at 21°C, 60-85% RH, and 15 h light. After 2.5 days of exposure, cups were inspected for dead larvae. Analysis of variance for unequal sample sizes was used because a replicate mean for Larvin at 1 lb was spurious.
The role of the pseudoknot at the 3' end of turnip yellow mosaic virus RNA in minus-strand synthesis by the viral RNA-dependent RNA polymerase (1997)

The tRNA-like structure at the 3' end of turnip yellow mosaic virus (TYMV) RNA was studied in order to determine the role of this structure in the initiation of minus-strand synthesis in vitro. Deletions in the 5'-to-3' direction up to the pseudoknot structure did not result in a decrease of transcription efficiency. However, transcription efficiency was reduced twofold when a fragment of 21 nucleotides, comprising the 3'-terminal hairpin, was used as a template. tRNA(Phe) from yeast, Escherichia coli 5S rRNA, and the 3'-terminal 208 nucleotides of alfalfa mosaic virus RNA 3 could not be transcribed by the RNA-dependent RNA polymerase (RdRp) of TYMV. Various mutations in the sequences of loop regions L1 and L2 or of stem region S1 of the pseudoknot were tested to further investigate the importance of the pseudoknot structure. The results were compared with those obtained in an earlier study on aminoacylation with the same mutants (R. M. W. Mans, M. H. van Steeg, P. W. G. Verlaan, C. W. A. Pleij, and L. Bosch, J. Mol. Biol. 223:221-232; 1992). Mutants which still harbor a stable pseudoknot, as proven by probing its structure, have a transcription efficiency very close to that of the wild-type virus. Disruption of the pseudoknot structure, however, gives rise to a drop in transcription efficiency to about 50%. No indications of base-specific interactions between L1, L2, or S1 of the pseudoknot and the RdRp were found.
Controllable Formation of Nanoscale Patterns on TiO<sub>2</sub> by Conductive-AFM Nanolithography (2008)

We report on the nanopatterning of double-bond-terminated silane (5-hexenyltrichlorosilane, HTCS) molecules on titania (TiO2) using conductive atomic force microscopy (AFM). The influences of tip electrostatic potential and scanning velocity, relative humidity and of the repeated application of voltage on the topographic height, width, and hydrophilic and hydrophobic contrast of the resultant patterns were investigated. Tip voltage and tip velocity ( v) were applied between -10 V <or= V tip <or= +10 V and 100 nm/s <or= v <or= 2 microm/s during the lithography step(s), respectively. Average height and Lateral Force Mode (LFM) images of patterns were obtained with different values of (-10 V <or= V tip <or= -7 V) and v (100 nm/s <or= v <or= 2 microm/s). The average height of the patterns is seen to decrease for increasing v and decreasing V tip in both a single or repeated lithography step. No patterns were observed following a single or repeated lithography step for -5 V <or= V tip <or= +10 V. This conductive lithography technique results in nanoscale physiochemical manipulations of the HTCS molecules that are manifested as controllable step heights ranging from approximately 1-15 nm possessing different chemistries on the patterned and unpatterned areas. The use of conductive-AFM nanolithography for altering and manipulating double-bond-terminated molecules on TiO2 surfaces suggests a range of applications, including selective immobilization and assembly of functionalized inorganic nanoparticles and biomolecules.
Henri Bosco et l'Ère du soupçon (2002)

Henri Bosco and The Age of Suspicion 1 According to literary criticism, in his case heavily indebted to romanticism, Bosco is a writer out of his time. Yet a closer study of his works shows that he is fully modern, in particular because of the centrality of the narrator within his fiction; and if he is doubtlessly a believer, in contradistinction to most of his contemporaries, the point of his work is precisely to give the religious feeling a modern novelistic form.
Frequency response based multivariable control design for motion systems (2005)

In this paper, we discuss the design of multivariable motion controllers exploiting crosscouplings in the controller for open loop decoupling, disturbance rejection and feedforward decoupling. Using specific properties of motion systems, we illustrate that frequency response design methods can be extended to handle several multivariable control problems. Application to high performance motion systems shows significant improvement
Adaptation of thin-film photovoltaic technology for use in space (2002)

The anticipated deployment of large numbers of satellites in low Earth orbit (LEO) for global telecommunications networks renews interest in producing solar power systems that are lightweight, robust, resistant to radiation damage and relatively inexpensive. Promising near term thin-film candidates are amorphous silicon (a-Si), cadmium telluride (CdTe), and copper indium gallium diselenide (CIGS). The authors discuss the modifications that are necessary to adapt terrestrial thin-film technology for use in space. They characterize expected module performance and present results of tests performed on sample cells. They consider the possibility of achieving aggressive cost, weight and performance targets through the use of thin-film photovoltaic (PV) technology.
Pathogenesis of infectious bursal disease in embryonally bursectomized chickens. (1982)

The pathogenesis of infectious bursal disease (IBD) in intact chickens was compared with pathogenesis in chickens that had undergone embryonal bursectomy (EBX chickens), which were challenged at either 2 or 6 weeks of age. All EBX chickens were free of bursa remnants, and those challenged at 6 weeks of age failed to develop primary and secondary antibody responses to sheep red blood cells and bovine serum albumin. A direct fluorescent-antibody technique was used to study the course of infection in the bursa of Fabricius, spleen, thymus, cecal tonsils, and kidneys. EBX delayed but did not prevent the appearance of IBD-infected cells. Virus-positive cells were detected in the thymus of EBX chickens up to 18 days postinfection. Significantly more EBX chickens challenged at 6 weeks of age had hemorrhagic lesion in muscles and intestinal tract than comparable intact chickens had.
Power management strategy for solving power dispatch problems in MicroGrid for residential applications (2010)

This paper proposes a new method to manage the daily operation of MicroGrid (MG) for residential applications. Thorough discussion and simulations are conducted to clarify and highlight the principle of the method. Nonlinear optimization problem formulation is also performed. The proposed cost function takes into consideration the costs of the emissions NOx, SO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , and CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> as well as the operation and maintenance costs. The microgrid considered in this paper consists of wind turbine, micro turbine, diesel generator, photovoltaic array and fuel cell. The Mesh Adaptive Direct Search (MADS) is employed to minimize the cost function of the system while constraining it to meet the costumer demand and safety of the system. Finally, a comparative investigation aiming at assessing the efficiency and applicability of the method is carried out. The method is proven simple and remarkably fast.
KARAYA GUM (INDIAN GUM) HYPERSENSITIVITY (1940)

To Dr. Stearns S. Bullen,<sup>1</sup>of Rochester, N. Y., belongs the credit of first calling attention to karaya gum as an allergen, in reporting a case of perennial hay fever from this substance. The patient was a woman, and the source of the karaya gum was the wave set material used on her hair. The following year Feinberg<sup>2</sup>reported a case of asthma due to karaya gum. Recently, through personal communication, I have learned of additional cases of sensitivity to the gum from Dr. Ralph Bowen, of Oklahoma City,<sup>3</sup>Dr. John Mitchell,<sup>3</sup>of Columbus, Ohio, and Dr. John Sheldon,<sup>3</sup>of Ann Arbor, Mich. To the reported cases, I here add sixteen cases from my own practice. Attention is again called to karaya gum because of its widespread use in wave sets, the substance having almost supplanted flaxseed, quince seed, tragacanth and acacia for this purpose.
Modeling and Predicting Future Trajectories of Moving Objects in a Constrained Network (2006)

Advances in wireless sensor networks and positioning technologies enable traffic management (e.g. routing traffic) that uses real-time data monitored by GPS-enabled cars. Location management has become an enabling technology in such application. The location modeling and trajectory prediction of moving objects are the fundamental components of location management in mobile locationaware applications. In this paper, we model the road network and moving objects in a graph of cellular automata (GCA), which makes full use of the constraints of the network and the stochastic behavior of the traffic. A simulation-based method based on graphs of cellular automata is proposed to predict future trajectories. Our technique strongly differs from the linear prediction method, which has low prediction accuracy and requires frequent updates when applied to real traffic with velocity changes. The experiments, carried on two different datasets, show that the simulation-based prediction method provides higher accuracy than the linear prediction method.
Low loss diamond SAW devices by small grain size poly-crystalline diamond (2003)

We have successfully developed a poly-crystalline diamond film whose grain size is small, which is expected to have a low propagation loss in SAW devices. Using this diamond film, three kinds of narrow band SAW filters of the SiO/sub 2//ZnO/diamond/Si structure were fabricated with the center frequency from 2.5 to 5.0 GHz and the propagation losses in these filters were investigate. It was confirmed that the propagation loss with this diamond film is about two thirds of that with our previously studied diamond film.
Efficient MPEG video traffic shaping for the next generation Internet (2003)

The Internet Engineering Task Force (IETF) has defined the Guaranteed Service (GS) with firm delay and bandwidth guarantees in the Integrated Services model for supporting real-time services. Before setting up a GS flow, the traffic parameter of the source have to be specified in terms of a number of token bucket traffic descriptors. The source must conform to these descriptors by shaping its traffic. In this paper we study a novel traffic shaper for efficient transmission of MPEG video streams over GS. We develop an analytical model of the traffic shaper, and also carry out numerical simulation of the transmission performance to verify the analytical model. Our study also provides a methodology to determine the token bucket traffic descriptors that have to be specified during flow set up.
Heart rate recovery after exercise: relations to heart rate variability and complexity (2002)

Physical exercise is associated with parasympathetic withdrawal and increased sympathetic activity resulting in heart rate increase. The rate of post-exercise cardiodeceleration is used as an index of cardiac vagal reactivation. Analysis of heart rate variability (HRV) and complexity can provide useful information about autonomic control of the cardiovascular system. The aim of the present study was to ascertain the association between heart rate decrease after exercise and HRV parameters. Heart rate was monitored in 17 healthy male subjects (mean age: 20 years) during the pre-exercise phase (25 min supine, 5 min standing), during exercise (8 min of the step test with an ascending frequency corresponding to 70% of individual maximal power output) and during the recovery phase (30 min supine). HRV analysis in the time and frequency domains and evaluation of a newly developed complexity measure - sample entropy - were performed on selected segments of heart rate time series. During recovery, heart rate decreased gradually but did not attain pre-exercise values within 30 min after exercise. On the other hand, HRV gradually increased, but did not regain rest values during the study period. Heart rate complexity was slightly reduced after exercise and attained rest values after 30-min recovery. The rate of cardiodeceleration did not correlate with pre-exercise HRV parameters, but positively correlated with HRV measures and sample entropy obtained from the early phases of recovery. In conclusion, the cardiodeceleration rate is independent of HRV measures during the rest period but it is related to early post-exercise recovery HRV measures, confirming a parasympathetic contribution to this phase.
Oxygen concentration in milk of healthy and mastitic cows and implications of low oxygen tension for the killing of<i>Staphylococcus aureus</i>by bovine neutrophils (1988)

The partial pressure of O2 in milk from normal cows and from cows with mastitis was measured and the concentrations of O2 calculated. Oxygen levels of milk from normal cows were similar to those in venous plasma, but inflammation of the mammary gland led to a dramatic drop in O2 concentration to less than 10% of control values. Intracellular survival of Staphylococcus aureus strain M60 in bovine neutrophils was greater under anaerobic than aerobic conditions. The implications of low O2 concentrations in milk from infected mammary glands for the bactericidal activity of bovine neutrophils is discussed.
Tunable Bioadhesive Copolymer Hydrogels of Thermoresponsive Poly(<i>N</i>-isopropyl acrylamide) Containing Zwitterionic Polysulfobetaine (2010)

This work describes a novel tunable bioadhesive hydrogel of thermoresponsive N-isopropylacrylamide (NIPAAm) containing zwitterionic sulfobetaine methacrylate (SBMA). This novel hydrogel highly regulates general bioadhesive foulants through the adsorption of plasma proteins, the adhesion of human platelets and cells, and the attachment of bacteria. In this investigation, nonionic hydrogels of polyNIPAAm, zwitterionic hydrogels of polySBMA, and three copolymeric hydrogels of NIPAAm and SBMA (poly(NIPAAm-co-SBMA)) were prepared. The copolymeric hydrogels exhibited controllable temperature-dependent swelling behaviors and showed stimuli-responsive phase characteristics in the presence of salts. The interactions of these hydrogels with biomolecules and microorganisms were demonstrated by protein adsorption, cell adhesion, and bacterial attachment, which allowed us to evaluate their bioadhesive properties. An enzyme-linked immunosorbent assay (ELISA) with monoclonal antibodies was used to measure different plasma protein adsorptions on the prepared hydrogel surfaces. At a physiological temperature, the high content of the nonionic polyNIPAAm in poly(NIPAAm-co-SBMA) hydrogel exhibits a high protein adsorption due to the interfacial exposure of polyNIPAAm-rich hydrophobic domains. A relatively high content of polySBMA in poly(NIPAAm-co-SBMA) hydrogel exhibits reduced amounts of protein adsorption due to the interfacial hydration of polySBMA-rich hydrophilic segments. The attachment of platelets and the spreading of cells were only observed on polyNIPAAm-rich hydrogel surfaces. Interestingly, the incorporation of zwitterionic SBMA units into the polyNIPAAm gels was found to accelerate the hydration of the cell-cultured surfaces and resulted in more rapid cell detachment. Such copolymer gel surface was shown to be potentially useful for triggered cell detachment. In addition, the interactions of hydrogels with bacteria were also evaluated. The polySBMA-rich hydrogels exhibited evident antimicrobial properties when they were incubated with Gram-positive bacteria ( S. epidermidis ) and Gram-negative bacteria ( E. coli ). This work shows that the bioadhesive properties of poly(NIPAAm-co-SBMA) hydrogels can be effectively controlled via regulated nonionic and zwitterionic molar mass ratios. The tunable-bioadhesive behavior of temperature-sensitive poly(NIPAAm-co-SBMA) makes this biocompatible hydrogel appropriate for biomedical applications.
Gastroesophageal Reflux, Barrett Esophagus, and Esophageal Cancer (2002)

Gastroesophageal reflux disease (GERD), a condition commonly encountered in the primary care setting, is a risk factor for adenocarcinoma of the esophagus. Despite the ubiquity of the complaint, considerable uncertainty exists with respect to several basic questions, including when to perform endoscopy in patients with chronic reflux symptoms and how to address the cancer risk associated with GERD. These clinical vignettes illustrate common clinical questions encountered in caring for patients with GERD, especially as they relate to the issue of cancer risk. Applying data reviewed in the companion article, we propose practical answers to common clinical situations regarding care of patients with reflux. We also present an algorithm for treatment of patients with chronic GERD symptoms.
Fuzzy blending of materials (2004)

In this paper, we propose a novel method for free form surface modeling based on fuzzy logic technique. The presented method is dependent on finding control points of surface. The main objective of method is that; in case of knowing start and final points, a surface is to construct by modeling curves. Firstly, each curve is modeled and then a surface is generated by joining the created curves. As an application, the method is applied to 3D blending and some blended objects are given. Application results show the effectiveness and applicability of the proposed method.
Effects of sub‐antimicrobial dose doxycycline therapy on crevicular fluid MMP‐8, and gingival tissue MMP‐9, TIMP‐1 and IL‐6 levels in chronic periodontitis (2003)

Adjunctive SDD therapy can improve the clinical parameters and this clinical improvement is reflected by controlled level of MMP-8 in chronic adult periodontitis after the therapy.