gebhart/patrepeval huggingface dataset:
Reducing electricity cost through virtual machine placement in high performance computing clouds (2011)

In this paper, we first study the impact of load placement policies on cooling and maximum data center temperatures in cloud service providers that operate multiple geographically distributed data centers. Based on this study, we then propose dynamic load distribution policies that consider all electricity-related costs as well as transient cooling effects. Our evaluation studies the ability of different cooling strategies to handle load spikes, compares the behaviors of our dynamic cost-aware policies to cost-unaware and static policies, and explores the effects of many parameter settings. Among other interesting results, we demonstrate that (1) our policies can provide large cost savings, (2) load migration enables savings in many scenarios, and (3) all electricity-related costs must be considered at the same time for higher and consistent cost savings.
Time warp for efficient parallel logic simulation on a massively parallel SIMD machine (2002)

A variation of the time warp protocol for efficient parallel logic simulation on a massively parallel SIMD machine is proposed. A scheme in which each object has a single event queue instead of three queues needed in the conventional time warp protocol is developed for fast queue manipulation and small storage requirement. An immediate cancellation technique of the rollback mechanism of time warp is proposed which does not require the use of antimessages and works well for the single queue structure. To minimize the queue size needed for simulation, a lower bound of rollback at each object is computed and used to discard processed events with timestamps less than the bound. Even if extra work is needed for computing and delivering the lower bound, the simulation using the lower bound of rollback is faster than the time warp protocol since queue manipulation time is significantly saved. Preliminary experimental results of the time warp variation on the Connection Machine-2 indicate significant savings in time and space over the time warp protocol. Moreover, the proposed scheme is much faster than the Intermetric VHDL simulator.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
ChemInform Abstract: DIANILINO DERIVATIVES OF SQUARIC ACID (1975)

Abstract Bei der Umsetzung mit Anilin (II) in Dimethylformamid erhält man aus Quadratsäure (I) neben den 1,3‐Derivaten (III) die 1,2‐Disubstitutionsprodukte (IV).
User Centered Research for Interactive Television (2003)

This paper presents results from a qualitative user study. The aim of research was to include the future users of a new technology in the product design of interactive television programs. During the study, the study participants were interviewed. They were asked to answer questions about their television use and to comment on artist’s drawings presenting the possible future setup and equipment at home. The study resulted in users ’ stories and innovations of interactive applications for the future.
Blue light-emitting diode demonstrated as an ultraviolet excitation source for nanosecond phase-modulation fluorescence lifetime measurements (1997)

We have produced amplitude-modulated near-ultraviolet light, centered at 390 nm, using an inexpensive, commercially available blue light-emitting diode (LED). The LED was amplitude modulated with the +13 dBm ac output from a frequency generator while biased through a bias tee with 60 mA of dc current. The LED produced 45 to 54 μW of UV light over the modulation bandwidth of 0.01 to 200 MHz, when measured after optical filters to remove the residual blue output. Since the filter attenuated the UV output about 3 dB, more than 100 μW of UV light was initially produced. Modulated UV light was available to approximately 200 MHz, with a −3 dB point of 31 MHz, allowing the measurement of ns fluorescence lifetimes. The fluorescence lifetimes of standard fluorophores (9-cyanoanthracene and green fluorescent protein) were measured in the frequency domain using the phase-modulation technique, producing lifetimes that closely agree with those reported in the literature, confirming that the UV-emitting blue LED is practical for spectroscopic and sensor applications. When compared to a laser modulated with a Pockels cell, the LED was smaller, less expensive, required less power, generated less heat, and required less alignment. The ability to modulate the LED at high frequencies, along with the UV output, allows its use as an inexpensive UV light source in fluorescence lifetime optical sensors and even frequency-domain fluorometers.
3D IC process development for enabling chip-on-chip and chip on wafer multi-stacking at assembly (2015)

Along with the flow and the fundamental focus on 3D integration, is the study in enabling stacking as well as assessing the needs to make it comparable to current manufacturing standards. To do this we take a look on key essential elements of a manufacturing line and applying it to the stacking process. Key areas of focus is process stability, control and ability to reducing the bond parameters (time, temp and force). With this we take a look at the developments done to enable such a condition and allowing the gathering and analysis of relevant data for enabling chip-on-chip (CoC) and chip-on-wafer (CoW) stacking in assembly production. CoC and CoW bonding is a stacking scheme in the 3D IC integration flow where diced top dies are bonded individually, using thermocompression bonding (TCB), directly over a whole bottom wafer or individual chips. These two methods have their advantages and disadvantages during assembly. One is to bond each chip only on another individual chips diced prior stacking, which is identified as CoC. Another is to place multiple chips in a single whole wafer then do the dicing afterwards. Both can be configured to adapt for multi-stacking. In this paper, we present the applicability of each process to actual production. We place side by side advantages and disadvantages for both methods with actual bond results. We also take a look on major parameters involved and innovative solutions used to address challenges. Coverage of this paper involves CoC and CoW stacking. Experiments are done on units using no-flow underfill (NUF) and wafer-level underfill (WLUF). The study covers learning's on the process development of die multi-stacking on 3D IC applications The paper will cover parameters, equipment and materials involved during the CoC and CoW bonding process. The goal of the paper is to show process development advances on 3D integration.
Effect of a high‐protein diet on the gene expression of a trypsin‐sensitive, cholecystokinin‐releasing peptide (monitor peptide) in the pancreas (1991)

The adaptation to a high protein diet of the concentration and mRNA level of a trypsin-sensitive, cholecystokinin-releasing peptide (monitor peptide), which was proposed to be the mediator of the cholecystokinin release in response to protein intake, was investigated in the rat pancreas. Adult rats were placed on one of two isocaloric diets. One group was fed a 22% casein diet (control diet) and the other a 64% casein diet (high-protein diet) for 14 days. In order to quantify the monitor peptide separately from pancreatic secretory trypsin inhibitor (PSTI-II), which is highly similar in its amino acid and mRNA nucleotide sequences to the monitor peptide but has less cholecystokinin-releasing activity, we used specific assay methods: HPLC was used for determining the monitor peptide concentration in zymogen granules and a synthetic oligonucleotide probe for determining the mRNA of the monitor peptide in the pancreas. The concentrations in the zymogen granules and the mRNA levels in the pancreas of the two peptides increased in parallel during the adaptation to the high protein diet, indicating that these two peptides were under the same control during the adaptation. The concentration and mRNA level of the monitor peptide, which were measured after 0, 3, and 14 days, increased throughout the experiment period, as did the concentration of trypsin. This suggested that the monitor peptide and trypsin may respond to similar signals during the adaptation to a high protein diet and that this apparent coordination may facilitate the adaptation of the pancreas to the diet.
Short communication. Repellency and toxicity of oils from different origins on Myzus persicae Sulzer (Homoptera: Aphididae) in pepper (2003)

Three trials have been carried out to assess the repellency and toxicity of oils of different origins on Myzus persicae in pepper plants: a summer mineral oil, refined oils of soya and rapeseed and a crude fish oil. The results obtained suggest that tested oils, in particular fish oil, are feeding deterrents for apterous aphids. These oils did not cause repellency to alate aphids, since the alates freely chose to settle on either oil treated or untreated plants. Only plants treated with the standard insecticide (Cypermethrin) were not colonized by the alates and their nymphs. On the contrary, direct spray of pepper leaves infested with apterous aphids showed that oils were toxic for the aphids, since 12 h after spraying the mortality rates were equal or above 70% in all cases. By this time, among all the oils, the mineral oil showed the best control efficacy (12 h89% mortality rate, statistically comparable with the standard). However, at 36 h mineral oil mortality rate (90%) was similar to that of fish and rapeseed oils.
Electrolyte effects upon the polarographic reduction of alkyl halides in dimethyl sulfoxide (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrolyte effects upon the polarographic reduction of alkyl halides in dimethyl sulfoxideAlbert J. Fry and Richard L. KriegerCite this: J. Org. Chem. 1976, 41, 1, 54–57Publication Date (Print):January 1, 1976Publication History Published online1 May 2002Published inissue 1 January 1976https://pubs.acs.org/doi/10.1021/jo00863a012https://doi.org/10.1021/jo00863a012research-articleACS PublicationsRequest reuse permissionsArticle Views661Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cell Cycle Activation in Postmitotic Neurons is Essential for DNA Repair (2007)

Increasing evidence indicates that maintenance of neuronal homeostasis involves the activation of the cell cycle machinery in postmitotic neurons. Our recent findings suggest that cell cycle activation is essential for DNA damage-induced neuronal apoptosis. However, whether the cell division cycle also participates in DNA repair and survival of postmitotic, terminally differentiated neurons is unknown. Here, we tested the hypothesis that G(1) phase components contribute to the repair of DNA and are involved in the DNA damage response of postmitotic neurons. In cortical terminally differentiated neurons, treatment with subtoxic concentrations of hydrogen peroxide (H(2)O(2)) caused repairable DNA double strand breaks (DSBs) and the activation of G(1) components of the cell cycle machinery. Importantly, DNA repair was attenuated if cyclin-dependent kinases CDK4 and CDK6, essential elements of G(0) --> G(1) transition, were suppressed. Our data suggest that G(1) cell cycle components are involved in DNA repair and survival of postmitotic neurons.
Droplet jumping by electrowetting and its application to the three-dimensional digital microfluidics (2012)

We introduce droplet jumping by electrowetting (DJE), which stretches droplets to store energy for jumping by electrowetting. The capillarity-driven droplet jumping is effective to overcome the energy barrier, where the threshold for jumping is less than 100 V. We studied the detailed jumping mechanisms with regard to the jumping height and the energy conversion and demonstrated the transport of sessile droplets to upper surfaces under diverse electrode configurations. While the droplet jumping on the superhydrophobic surface is the primary focus of our research, DJE is also found to be possible on conventional Teflon surfaces, envisioning the three-dimensional droplet-based digital microfluidics.
Keeping up with Fitness (1962)

(1962). Keeping up with Fitness. Journal of Health, Physical Education, Recreation: Vol. 33, No. 2, pp. 73-74.
P‐49: Comparison of the Readability of Colour Head‐up Displays Using LED and Laser Light Sources (2010)

Abstract This paper compares the readability and colour performance of LED‐ and laser‐based head‐up displays for various ambient light conditions according to colour appearance model CIECAM02 and ISO 15008. It is found that laser‐based HUDs perform favourably in terms of readability and colourfulness compared to LCD‐based systems using either white or RGB‐LED illumination.
<scp>BLAST</scp> Algorithm (2014)

Abstract BLAST is an acronym for ‘Basic Local Alignment Search Tool’. Members of the BLAST family of database search programs take as input a query deoxyribonucleic acid (DNA) or protein sequence, and search a DNA or protein sequence database for similarities that may indicate homology. The programs implement variations of the BLAST algorithm, which is a heuristic method for rapidly finding local alignments with scores sufficiently high to be statistically significant. The BLAST algorithm first seeks near‐perfect matches to words within a query sequence, and then extends these matches to determine whether they are contained within longer, high‐scoring local alignments. BLAST approximates the rigorous Smith–Waterman local alignment algorithm; it permits a chance of missing weak sequence similarities in exchange for greatly increased speed. Key Concepts: Local sequence alignment is used for similarity searches of sequence databases. The Smith–Waterman algorithm is a rigorous dynamic programming method for finding optimal local alignments. BLAST is a fast, heuristic approximation to the Smith–Waterman algorithm. An analytic theory describes the optimal scores of ungapped local alignments. The statistical parameters for BLAST's gapped local alignments are precomputed by random simulation. Very efficient algorithms exist for finding perfect or near‐perfect word matches. BLAST finds weak local alignments if they contain near‐perfect word matches. BLAST provides a trade‐off between speed and the probability of missing statistically significant alignments. A variety of specialized BLAST programs are adapted to searching DNA or protein sequence databases with DNA or protein query sequences. PSI‐BLAST increases the sensitivity of protein database searches by constructing a protein profile from the results of a regular BLAST search.
The Epidermal Growth Factor-Seven Transmembrane (EGF-TM7) Receptor CD97 Is Required for Neutrophil Migration and Host Defense (2004)

The epidermal growth factor-seven transmembrane (EGF-TM7) family is a group of seven-span transmembrane receptors predominantly expressed by cells of the immune system. Family members CD97, EGF module-containing mucin-like receptor (EMR) 1, EMR2, EMR3, EMR4, and EGF-TM7-latrophilin-related protein are characterized by an extended extracellular region with a variable number of N-terminal EGF-like domains. EGF-TM7 receptors bind cellular ligands as demonstrated by the interaction of CD97 with decay accelerating factor (CD55) and dermatan sulfate. Investigating the effect of newly generated mAb on the migration of neutrophilic granulocytes, we here report for the first time in vivo data on the function of CD97. In dextran sulfate sodium-induced experimental colitis, we show that homing of adoptively transferred neutrophils to the colon was significantly delayed when cells were preincubated with CD97 mAb. The consequences of this defect in neutrophil migration for host defense are demonstrated in a murine model of Streptococcus pneumoniae-induced pneumonia. Mice treated with CD97 mAb to EGF domain 1 (1B2) and EGF domain 3 (1C5) displayed a reduced granulocytic inflammatory infiltrate at 20 h after inoculation. This was associated with a significantly enhanced outgrowth of bacteria in the lungs at 44 h and a strongly diminished survival. Together, these findings indicate an essential role for CD97 in the migration of neutrophils.
Disintegrating Force and Tablet Properties (1981)

AbstractThe development of a disintegrating force inside the tablet due to the liquid/solid contact depends on a proper wetting of the material and occur according to saturation kinetics.The aim of the present work is the evaluation of such a force development in relation to the characteristics of the tablet in particular to the compression force.For this purpose, the disintegrating force of different tablets formulations has been measured by means of a previously described apparatus.The results obtained show that a new evaluation of a compact disintegration characteristics may be obtained through the determination of such parameters as the maximum force developed (y0) and the time of the half maximum force development (b).
Retinals and Retinols Induced By Estrogen in the Blood Plasma of <i>Xenopus Laevis</i> (1993)

Injection of estrogen into male Xenopus laevis induced the appearance of retinals (retinal and 3-dehydroretinal) and a considerable increase in the amount of retinols (retinol and 3-dehydroretinol) in the blood plasma. These retinoids were mainly in the all-trans form. Without estrogen injection, retinols were normally found in the blood plasma of both males and females, but only trace amounts of retinals were detected and these were restricted to the plasma of females. The proteins in the blood plasma of estrogen-injected males were separated into two fractions. One fraction included vitellogenin, the precursor of egg yolk proteins, and the other contained some plasma proteins other than vitellogenin. Retinals were detected in the former and retinols in the latter. It is suggested that retinals are bound to vitellogenin and are taken up into oocytes in the process of vitellogenesis.
Induction of Cell Cycle Arrest and Morphological Differentiation by Nurr1 and Retinoids in Dopamine MN9D Cells (2001)

Dopamine cells are generated in the ventral midbrain during embryonic development. The progressive degeneration of these cells in patients with Parkinson's disease, and the potential therapeutic benefit by transplantation of in vitro generated dopamine cells, has triggered intense interest in understanding the process whereby these cells develop. Nurr1 is an orphan nuclear receptor essential for the development of midbrain dopaminergic neurons. However, the mechanism by which Nurr1 promotes dopamine cell differentiation has remained unknown. In this study we have used a dopamine-synthesizing cell line (MN9D) with immature characteristics to analyze the function of Nurr1 in dopamine cell development. The results demonstrate that Nurr1 can induce cell cycle arrest and a highly differentiated cell morphology in these cells. These two functions were both mediated through a DNA binding-dependent mechanism that did not require Nurr1 interaction with the heterodimerization partner retinoid X receptor. However, retinoids can promote the differentiation of MN9D cells independently of Nurr1. Importantly, the closely related orphan receptors NGFI-B and Nor1 were also able to induce cell cycle arrest and differentiation. Thus, the growth inhibitory activities of the NGFI-B/Nurr1/Nor1 orphan receptors, along with their widespread expression patterns both during development and in the adult, suggest a more general role in control of cell proliferation in the developing embryo and in adult tissues.
Noise reduction in hearing aids: a review. (2001)

Background noise is particularly damaging to speech intelligibility for people with hearing loss. The problem of reducing noise in hearing aids is one of great importance--and great difficulty. The problem has been addressed in many different ways over the years. The techniques used range from relatively simple forms of filtering to advanced signal processing methods. This paper provides a brief overview, in nontechnical language, of the issues involved and the various approaches to solving the problem.
A Narrow-Spectrum Vertical-Cavity Surface-Emitting Laser Incorporating a Multimode Fiber Bragg Grating (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text T. Mizunami and T. Hamada, "A Narrow-Spectrum Vertical-Cavity Surface-Emitting Laser Incorporating a Multimode Fiber Bragg Grating," in Bragg Gratings, Photosensitivity, and Poling in Glass Waveguides, T. Erdogan, E. Friebele, and R. Kashyap, eds., Vol. 33 of OSA Trends in Optics and Photonics Series (Optical Society of America, 1999), paper AA6. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The research of increment clustering algorithm based on core tree (2011)

Clustering analysis in data mining deploys many traditional methods.All these methods have not been considered large volume data sets.However,to efficiently obtain knowledge from large amount of data sets is the top-leading problem in data mining area.Basing on the K-means center points algorithm and the BIRCH increment algorithm,the author poses the concept of core-tree which could make up the weakness of these two algorithms,That is,using center point to indicate the summary information in BIRCH,and using class core to improve the efficiency of center point orientation.Therefore,clustering analysis in aims at improving efficiency of algorithm and ability of processing variant types of data.
Lung Tissue Engineering Technique with Adipose Stromal Cells Improves Surgical Outcome for Pulmonary Emphysema (2006)

The present findings demonstrate the therapeutic potential of cell therapy using ASCs with a scaffold for selective delivery of HGF to remnant lungs, which resulted in enhancement of compensatory growth, after surgical resection. This approach may provide a new strategy for lung tissue engineering to improve LVRS outcome.