gebhart/patrepeval huggingface dataset:
The clinical characteristics and outcomes of carotid body tumors in Chinese patients (2020)

This study aims to investigate the clinical characteristics and outcomes of carotid body tumors in Chinese patients in the last decade. A systematic search was conducted without limits and included studies published between January 2006 and December 2016 according to PubMed, the Chinese Science Citation Database, the China Science Periodical Database and the China National Knowledge Infrastructure. Relevant synonyms for the search terms "paraganglioma" and "carotid body tumor" were applied, and the clinical data were evaluated and analyzed. There were 1810 cases of CBTs reported in the last decade, of which females accounted for 60.22%, and the mean age was 40.60 years, with most cases being sporadic (98.51%). Surgical resection was performed in 1791 cases: vessel repair occurred in 38.88% of the cases, carotid ligation occurred in 1.42% of the cases, and 1.05% of the patients refused treatment. Some patients underwent selective embolization, and the results showed that embolization could decrease procedure time and blood loss (P < .01). Stroke and death occurred in 1.95% and 0.39% of patients, respectively. Malignant CBTs accounted for 4.30% of cases, and the metastatic sites involved were local metastasis (46.88%), lung (31.25%), bone (21.88%), liver (12.50%), and brain (9.38%). The overall survival rate was 98.87% 36 months after the procedure, and the survival rate of metastatic cases was 56.25% 6 months after recurrence; however, only 21.88% of metastatic cases received radiotherapy. The CBTs of Chinese patients showed some clinical features that were different from those of Western patients.
Detectietest voor droge mollen op komst (2006)

Hoe kunnen droge mollen worden bestreden? PPO-Paddestoelen en Plant Research International (PRI) hebben samen gewerkt aan de ontwikkeling van een moleculaire detectietest om droge mollen te detecteren. Deze test komt in de afrondende fase. Er wordt naar gestreefd om de eerste monsters uit de praktijk in 2006 te analyseren. Op basis van informatie over het voorkomen van Verticillium fungicola, waardoor droge mollen worden veroorzaakt, kan een champignonteler maatregelen treffen
Consensus Clusterings (2007)

In this paper we address the problem of combining multiple clusterings without access to the underlying features of the data. This process is known in the literature as clustering ensembles, clustering aggregation, or consensus clustering. Consensus clustering yields a stable and robust final clustering that is in agreement with multiple clusterings. We find that an iterative EM-like method is remarkably effective for this problem. We present an iterative algorithm and its variations for finding clustering consensus. An extensive empirical study compares our proposed algorithms with eleven other consensus clustering methods on four data sets using three different clustering performance metrics. The experimental results show that the new ensemble clustering methods produce clusterings that are as good as, and often better than, these other methods.
Specificity and methods of transmission of cucumber necrosis virus by<i>Olpidium radicale</i>zoospores (1982)

(1982). Specificity and methods of transmission of cucumber necrosis virus by Olpidium radicale zoospores. Canadian Journal of Plant Pathology: Vol. 4, No. 2, pp. 134-142.
Structure–property relationships of ionene polymers (1987)

Abstract The synthesis of new ionenes was accomplished by the reaction of novel diamines and dihalides. A new class of crosslinkable ionenes was made possible by the synthesis of tertiary diamines with acrylate functionality, generated ultimately from diepoxides and secondary amines. Other tertiary diamines were produced by endcapping of diols with tolylene diisocyanate, followed by reaction with N , N ‐dimethylethanolamine and also termination of living poly(tetrahydrofuran) polymer with dimethylamine. New dihalides were produced by the opening of diepoxides with ω‐bromoacids. These diamines and dihalides underwent Menschutkin reactions providing novel ionenes for structure–property relationship studies. Correlations were drawn concerning amine nucleophilicity, dihalide nucleofugascity, and molecular weight. Stress–strain and thermal data reflected the effects of ionic domains and large flexible segments in the polymers. Also considered were the electrical conductivity, moisture–vapor transmission, and oxygen permeability of these materials.
Advanced glycation end products are eliminated by scavenger-receptor-mediated endocytosis in hepatic sinusoidal Kupffer and endothelial cells (1997)

Long-term incubation of proteins with glucose leads to the formation of advanced glycation end products (AGE). Physiological aspects of the catabolism of non-enzymically glycated proteins were studied in vivo and in vitro. AGE-modified BSA (AGE-BSA) was a mixture of high-Mr (cross-linked), monomeric and low-Mr (fragmented) AGE-BSA. After intravenous administration in rat, all three fractions of AGE-BSA accumulated extremely rapidly and almost exclusively in liver. Uptake in liver endothelial, Kupffer and parenchymal cells accounted for approx. 60%, 25% and 10-15% respectively of hepatic elimination. Both cross-linked and monomeric AGE-BSA were efficiently taken up and degraded in cultures of purified liver endothelial and Kupffer cells. Endocytosis of AGE-BSA by these cells was inhibited by several ligands for the scavenger receptor. Although 125I-Hb was not endocytosed in vitro, 125I-AGE-Hb was effectively endocytosed by a mechanism that was subject to inhibition by AGE-BSA. Endocytosis of N-terminal propeptide of type I procollagen, a physiological ligand for the scavenger receptor, was effectively inhibited by AGE-Hb and AGE-BSA. We conclude that AGE-modification renders macromolecules susceptible for elimination via the scavenger receptor of both liver endothelial and Kupffer cells.
Mammostrat® as a tool to stratify patients at risk of recurrence during endocrine therapy. (2009)

Abstract Abstract #3026 Background: Patients with early stage ER+ve breast cancer have excellent prognosis with ca 90% 5 year disease free survival when treated with endocrine therapy. However for patients who relapse during endocrine therapy additional adjuvant therapy options, such as chemotherapy, are indicated. The challenge is to prospectively identify such patients. The Mammostrat® test comprises 5 simple immunohistochemical markers (p53, HTF9C, CEACAM5, NDRG1, SLC7A5) which stratify node negative tamoxifen treated patients into low, moderate and high risk groups. We have now tested the efficacy of this panel in a mixed population of node positive/node negative cases treated in a single centre (Edinburgh Breast Unit) with breast conserving surgery.&#x2028; Methods: TMAs from a consecutive series (1981-98) of 1,812 women managed by wide local excision and postoperative radiotherapy (45Gy in 20-25 fractions) were collected following appropriate ethical review. Of 1390 cases stained, 197 received no adjuvant hormonal or chemotherapy, 1044 received tamoxifen only as adjuvant therapy and 149 received a combination of hormonal and chemotherapy. Median age at diagnosis was 57, 71% were post-menopausal, 23.9% node positive, median size was 1.5 cm. Samples were stained, using triplicate 0.6mm2 TMA cores and positivity for p53, HTF9C, CEACAM5, NDRG1, SLC7A5 recorded as previously described. Each case was assigned a Mammostrat score and RFS and OS analysed by marker positivity and Mammostrat score.&#x2028; Results: Staining for all 5 antibodies was successful in 1174/1390 (84%) of cases. In the primary analysis of 531 N0/ER+ve Tamoxifen only treated patients Mammostrat was significantly associated with relapse free survival (RFS) in univariate (p=0.025) & multivariate proportional hazards analysis (p=0.01, HR=1.3, 95%C.I. 1.08-1.74). PgR, multifocality and menopausal status were significant co-variates (p&lt;0.05, HR 0.89, 2.0 & 0.6 respectively). The Nottingham prognostic index was non-significant. Of the 5 antibodies, only p53 (p=0.04) was independently predictive of survival.&#x2028; In a secondary univariate analysis of 781 patients (including N+ve and chemo/tam treated patients) Mammostrat was predictive of RFS & OS (p&lt;0.01) with NDRG1/CEACAM5/p53 also predictive of RFS(p&lt;0.05). However Mammostrat was not independent of nodal status, pathological size, grade or multifocality in a proportional hazards analysis.&#x2028; Discussion: In the Edinburgh BCS population Mammostrat was predictive of RFS (both local and distant relapses) in N-ve/ER+ve patients treated with tamoxifen alone irrespective of menopausal status. There was a strong correlation between Mammostrat scores and grade, however, in a multivariate analysis Mammostrat contributed significantly to prognostication along with PgR, multifocality and menopausal status. Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 3026.
Enhancing information flow in a retail supply chain using RFID and the EPC network (2008)

RFID technology and the Electronic Product Code (EPC) network have attracted considerable interest from businesses and academics in recent years. The interest is even stronger in the retail industry where firms such as Best Buy, Wal-Mart, Tesco, Target and Metro AG are capitalizing on the potential of these technologies. Based on a field study conducted in a three-layer retail supply chain, this paper tests several scenarios integrating Radio Frequency Identification (RFID) technology and the EPC network and evaluates, in a laboratory setting, their potential as enablers of information flow within a retail supply chain. Using an open-loop adoption strategy, our preliminary results indicate that RFID technology and the EPC network (i) hold some potential that can be grasped through Business Process Management (BPM), (ii) enable the synchronization of information flow with product flow in a given supply chain, and thus, (iii) provide a better level of information integration between supply chain members. The results suggest that these new waves of information technology (IT) could in fact provide end-to-end information flow between supply chain members.
Microwave detection of breast cancer: a study of tumor response variations (2002)

Microwave confocal imaging was recently introduced for breast tumor detection. This paper describes the physical configurations and image reconstruction algorithms of the authors' proposed system. The number of antennas required for tumor detection is explored. The tumor response obtained in the images is examined with different model tumor sizes and variations on the image reconstruction techniques.
Exact Results in the Kondo Problem: Equivalence to a Classical One-Dimensional Coulomb Gas (1969)

We demonstrate an exact equivalence between a Kondo problem and the thermodynamics of a classical one-dimensional gas with alternating charges and a logarithmic potential. This classical gas has a critical point.
Learning algorithm of environmental recognition in driving vehicle (1995)

We consider the problem of recognizing driving environments of a vehicle by using the information obtained from some sensors of the vehicle. Previously, we presented recognition algorithms based on a usual method of pattern matching using the distance on a vector space and fuzzy reasoning. These algorithms can not be applied to meet the demands of nonstandard drivers and changes of vehicle properties, because the standard pattern or membership function for the pattern matching is always fixed. Thus to cover such weakness we present adaptive recognition algorithms with adaptive change of the standard pattern and membership function. In this work, we put forward a fuzzy supervisor in the learning process. Also, we present an algorithm into which a new learning method is introduced to improve the performance of the previous ones and to meet the above demands.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Xerostomia: an update for clinicians (2010)

Saliva plays an important protective role in the oral environment, and reductions in saliva quantity are known to increase the risk of oral diseases. Importantly, xerostomia or the perception of a dry mouth is now being recognized as an important risk factor for dental diseases. Furthermore, the subjective sensation of a dry mouth is a debilitating condition in itself that impacts on the quality of life of sufferers. With approximately 1 in 5 people reporting some form of dry mouth, and an increasing prevalence in the elderly, it is important for clinicians to have a thorough understanding of this problem. The aim of this paper is to review some of the literature relating to xerostomia in order to provide an evidence based update for clinicians.
Platelet factor 4 (PF4) and heparin released platelet factor 4 (HR-PF4) in diabetes mellitus. Effect of the duration of the disease. (1986)

Several investigators have reported an altered platelet function in diabetes mellitus as measured by elevated levels of platelet specific proteins platelet factor 4 (PF4) and B-thromboglobulin (BTG). We studied 20 insulin dependent (IDD), 20 non insulin dependent (NIDD) diabetic males without overt clinical symptoms of cardiovascular disorders and 30 normal controls. We evaluated PF4, BTG and heparin released platelet factor 4 (HR-PF4) as measured 2.5 minutes after a bolus injection of 5,000 I.U. of a commercial mucous heparin. The patients showed normal levels of both PF4 and BTG. Furthermore HR-PF4 failed to show statistically significant variation between patients and controls. However when the diabetics were divided on the basis of the duration of the disease, the IDD had an increased HR-PF4 mean level and the trend became statistically significant when diabetes existed more than 17 years (patients HR-PF4 149.1 ng/ml, range 17.3-194; controls HR-PF4 110.9 ng/ml range 50-160, less than p less than 0.05). NIDD failed to reveal the same pattern. Although the significance of HR-PF4 is unknown, insulin dependent diabetes mellitus after many years could cause a potentially dangerous, silent vascular damage with enhanced platelet vessel wall interaction as measured by an elevated HR-PF4.
A Systematic Review of High Quality Diagnostic Tests for Chagas Disease (2012)

Sensitivity and specificity of serological assays for the diagnosis of Chagas disease appear less accurate than previously thought. Suggestions to improve the accuracy of reporting include the enrollment of patients in a prospective manner, double blinding, and providing an explicit method of addressing subjects that have an indeterminate diagnosis by either the reference standard or index test.
Glycolipid depletion in antimicrobial therapy (2003)

Mucosal pathogens target sites of infection through specific adherence to host glycoconjugate receptors. As a consequence, depletion of such receptors from the cell surface may be expected to inhibit attachment, impair bacterial colonization and reduce the activation of mucosal inflammation. We have used the glucose analogue and glycosphingolipid (GSL) biosynthesis inhibitor N-butyldeoxynojirimycin (NB-DNJ) to deplete human uroepithelial cells and the murine urinary tract mucosa of receptors for P-fimbriated Escherichia coli. NB-DNJ blocks the ceramide-specific glucosyltransferase, which catalyses the formation of glucosyl ceramide (GlcCer), the precursor for GSLs. The inhibitor was shown to decrease the GSL content in a dose-dependent way, and depletion markedly inhibited P-fimbriated bacterial attachment in vitro. NB-DNJ-fed C3H/HeN mice were depleted of GSLs in vivo and showed reduced susceptibility to experimental urinary tract infection with P-fimbriated E. coli. The mucosal inflammatory response was impaired, as shown by reduced chemokine secretion and lower neutrophil recruitment, and the bacteria colonized the urinary tract less efficiently than in normal mice. These results confirmed the role of P fimbriae-mediated adherence for colonization and inflammation and point to an interesting alternative to antibiotic treatment for urinary tract infection.
VCR: Virtual Capture and Replay for Performance Testing (2008)

This paper proposes a novel approach to performance testing, called virtual capture and replay (VCR), that couples capture and replay techniques with the checkpointing capabilities provided by the latest virtualization technologies. VCR enables software performance testers to automatically take a snapshot of a running system when certain critical conditions are verified, and to later replay the scenario that led to those conditions. Several in-depth analyses can be separately carried out in the laboratory just by rewinding the captured scenario and replaying it using different probes and analysis tools.
Measurement and control of steel sheet surface cleanliness (2002)

In this paper, two techniques allowing in-line control of the surface cleanliness of steel sheets are presented. Surface pollution is produced during cold rolling and temper rolling. It consists roughly of oil and iron fines. The residual iron content can be measured by a first system based on infrared light reflection. The second system developed for the determination of oil pollution is based on an UV photoemission technique.
Robust generation of high‐quality unstructured meshes on realistic biomedical geometry (2005)

Abstract In this paper, we propose efficient and robust unstructured mesh generation methods based on computed tomography (CT) and magnetic resonance imaging (MRI) data, in order to obtain a patient‐specific geometry for high‐fidelity numerical simulations. Surface extraction from medical images is carried out mainly using open source libraries, including the Insight Segmentation and Registration Toolkit and the Visualization Toolkit, into the form of facet surface representation. To create high‐quality surface meshes, we propose two approaches. One is a direct advancing front method, and the other is a modified decimation method. The former emphasizes the controllability of local mesh density, and the latter enables semi‐automated mesh generation from low‐quality discrete surfaces. An advancing‐front‐based volume meshing method is employed. Our approaches are demonstrated with high‐fidelity tetrahedral meshes around medical geometries extracted from CT/MRI data. Copyright © 2005 John Wiley & Sons, Ltd.
Effect of Rhodamine-B on the electrodeposition of lead on copper. Revision (1984)

Rhodamine-B chloride (10..mu..M) has been used as a model plating additive in a study of the electrodeposition of Pb from 1 M NaClO/sub 4/, 0.5 and 5 mM Pb/sup + +/ (pH 3) on Cu. Ellipsometer measurements during cyclic voltammetry have shown that the addition of dye results in a more compact bulk deposit than obtained in its absence. It also prevents complete monolayer coverage during formation of the Pb underpotential deposit and shifts the bulk deposition peak to more cathodic potentials during the first potential cycle. Dye effects on potential and micromorphology disappear during subsequent cycling, but reappear after relaxation periods at open circuit. Depletion and readsorption of dye on the surface have been confirmed by spectroscopic ellipsometry. Different optical film models have been investigated for the interpretation of spectroscopic ellipsometer measurements by use of multidimensional analysis. 15 figures.
Soft X-Ray Reduction Lithography Using Multilayer Mirrors (1991)

A feasibility study on soft X-ray reduction lithography using multilayer mirrors has been performed. An exposure wavelength range of 80 to 110 Å is proposed as the most suitable with current technology considering the optic design, the reflectivity of the multilayer, and the resist characteristics. With the aim of providing multilayers with very sharp interfaces and high reflectivity, we attempted to improve the multilayer fabrication process, with one result being the fabrication of an amorphous Mo/Si multilayer, by controlling substrate temperature. Experimental results of 0.2-µm pattern replication using a multilayer reflection mask are presented.
Spermine and Spermidine as Gating Molecules for Inward Rectifier K <sup>+</sup> Channels (1994)

Inward rectifier K+ channels pass prominent inward currents, while outward currents are largely blocked. The inward rectification is due to block by intracellular Mg2+ and a Mg(2+)-independent process described as intrinsic gating. The rapid loss of gating upon patch excision suggests that cytoplasmic factors participate in gating. "Intrinsic" gating can be restored in excised patches by nanomolar concentrations of two naturally occurring polyamines, spermine and spermidine. Spermine and spermidine may function as physiological blockers of inward rectifier K+ channels and "intrinsic" gating may largely reflect voltage-dependent block by these cations.
An <i>LRRK2</i> mutation as a cause for the parkinsonism in the original <i>PARK8</i> family (2005)

We detected a missense mutation in the kinase domain of the LRRK2 gene in members with autosomal dominant Parkinson's disease of the Japanese family (the Sagamihara family) who served as the basis for the original defining of the PARK8 Parkinson's disease locus. The results of the Sagamihara family, in combination with the unique pathological features characterized by pure nigral degeneration without Lewy bodies, provided us with valuable information for elucidating the protein structure-pathogenesis relationship for the gene product of LRRK2. We did not detect this mutation or other known mutations of the LRRK2 gene in Japanese patients with sporadic Parkinson's disease.
Surface analyses by a triboelectric charging technique (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface analyses by a triboelectric charging techniqueHarry W. Gibson, John M. Pochan, and F. C. BaileyCite this: Anal. Chem. 1979, 51, 4, 483–487Publication Date (Print):April 1, 1979Publication History Published online1 May 2002Published inissue 1 April 1979https://pubs.acs.org/doi/10.1021/ac50040a006https://doi.org/10.1021/ac50040a006research-articleACS PublicationsRequest reuse permissionsArticle Views316Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Measurement of ^12CO_2:^13CO_2 ratios for medical diagnostics with 16-μm distributed-feedback semiconductor diode lasers (1993)

We have observed some of the absorption lines from the molecules (12)CO(2) and (13)CO(2)in the 1.6-µm spectral region with the use of specially fabricated single-mode InGaAsP distributed-feedback semiconductor diode lasers. Using a 23.6-m-long multipass absorption cell in combination with radio-frequency modulation and detection techniques, we measured the (12)CO(2):(13)CO(2) isotopic ratio of two specific lines at 6253.73 and 6253.90 cm(-1) with sufficient precision for diagnostic medical tests that analyze CO(2) on human breath.