gebhart/patrepeval huggingface dataset:
The construction of a zwitterionic PVDF membrane surface to improve biofouling resistance (2013)

Biofouling of membrane surfaces by the attachment of microorganisms is one of the major obstacles for ensuring the effectiveness of membrane separation processes. This work presents the construction of a zwitterionic PVDF membrane surface with improved resistance to biofouling. An amphiphilic copolymer of poly(vinylidene fluoride)-graft-poly(N,N-dimethylamino-2-ethylmethacrylate) (PVDF-g-PDMAEMA) was first synthesized via radical graft copolymerization and then the flat membrane was cast with immersed phase inversion. The PDMAEMA side chains tended to aggregate on the membrane surface, pore surface and internal pore channel surface, and were converted with 1,3-propane sultone (1,3-PS) to yield a zwitterionic membrane surface. A higher conversion of PDMAEMA chains and distribution of zwitterions were obtained using a longer treatment time. A biofouling assay indicated that incorporation of zwitterions suppressed the adsorption of extracellular polymer substances and the adhesion of Escherichia coli bacterial cells to the membrane surface, endowing the membrane with a high flux recovery and biofouling resistance in the filtration process.
A questão regional no pensamento de Antonio Gramsci e Celso Furtado (2009)

Este artigo analisa a questão regional na interpretação de dois intelectuais do século XX: Antonio Gramsci e Celso Furtado. Na primeira parte, aborda o enfoque da questão do Mezzogiorno na Itália por Gramsci; na segunda, trata da leitura de Furtado acerca da questão do nordeste no Brasil. Na última parte, procede-se a um paralelo entre os dois autores, apontando semelhanças e diferenças entre suas interpretações e projetos.
Chemical Sorption of Carbon Dioxide (CO<sub>2</sub>) on Lithium Oxide (Li<sub>2</sub>O) (2006)

The behavior of lithium oxide (Li2O) under an atmosphere of CO2 was studied using thermogravimetric analysis, scanning electron microscopy, and X-ray diffraction techniques. Results show that Li2O can be used for CO2 retention. It is a better absorbent than other lithium ceramics. A chemisorption topochemical reaction is proposed to explain the sorption of CO2. The kinetic parameters were obtained. First, the CO2 sorption is controlled by a first-order reaction. Later, CO2 sorption depends on the diffusion of lithium through the formed shell of Li2CO3, with an extraordinary increase of the diffusion at 600 °C, due to an unusual increase of lithium mobility.
Special interfaces: military transformations (2003)

The objective of this paper is to review the mechanism of military transformations. Evidence is presented showing that these diffusionless transformations, which involve shear dominant deformation concomitant with interface motion in stiff engineering materials, occur by motion of disconnections along the interfaces. Disconnections are interfacial line-defects that exhibit both dislocation and step character. In the theoretical part of the review, topological arguments are used to identify the constraints on diffusionless motion of disconnections, and it is proposed that five criteria (one compositional, three crystallographic and one relating to the intrinsic mobility of disconnections) must be satisfied for feasible transformations. Subsequently, experimental observations in heterophase interfaces, namely, martensitic transformations, and homophase materials, i.e. deformation twinning and intervariant boundaries, are presented and interpreted in this framework. The generic nature of this mechanistic approach is further illustrated by a military transformation in a soft biological material, and a diffusive-displacive transformation in an intermetallic alloy where the compositional criterion is relaxed.
Quench Protection for HTS Current Leads by Adding Connected HTS Bridges (2013)

Superconducting magnet systems operated at cryogenic temperature require high temperature superconducting (HTS) current leads to reduce the heat intrusion from the power supply at room temperature. However, some kinds of accidents, such as cryogenic failure, can cause a quench in the HTS current lead. Since the current conducting through the HTS current lead is very large, the quench in a HTS part can lead to a severe device failure. Therefore a study of a protection method for the HTS current lead is important. Generally, the HTS part of current lead used in large scale magnet systems has multiple separated HTS tape strands. They are electrically not connected or poorly connected. Therefore the quench in one strand affects other strands in current lead by applying additional loads for the other parts of the HTS current lead. In this paper, a strand-to-strand bridging method with HTS tapes is proposed as a quench protection method. Small scale HTS current leads with 2G HTS tapes and the suggested bridging method have been fabricated and tested.
Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer (2011)

STAT5 consists of two proteins, STAT5A/B, that impact mammary cell differentiation, proliferation, and survival. In normal development, STAT5 expression and activity are regulated by prolactin signaling with JAK2/ELF5, EGF signaling networks that include c-Src, and growth hormone, insulin growth factor, estrogen, and progesterone signaling pathways. In cancer, erythropoietin signaling can also regulate STAT5. Activation levels are influenced by AKT, caveolin, PIKE-A, Pak1, c-Myb, Brk, beta-integrin, dystroglycan, other STATs, and STAT pathway molecules JAK1, Shp2, and SOCS. TGF-β and PTPN9 can downregulate prolactin- and EGF-mediated STAT5 activation, respectively. IGF, AKT, RANKL, cyclin D1, BCL6, and HSP90A lie downstream of STAT5.
Genetic-based EM algorithm for learning Gaussian mixture models (2005)

We propose a genetic-based expectation-maximization (GA-EM) algorithm for learning Gaussian mixture models from multivariate data. This algorithm is capable of selecting the number of components of the model using the minimum description length (MDL) criterion. Our approach benefits from the properties of Genetic algorithms (GA) and the EM algorithm by combination of both into a single procedure. The population-based stochastic search of the GA explores the search space more thoroughly than the EM method. Therefore, our algorithm enables escaping from local optimal solutions since the algorithm becomes less sensitive to its initialization. The GA-EM algorithm is elitist which maintains the monotonic convergence property of the EM algorithm. The experiments on simulated and real data show that the GA-EM outperforms the EM method since: 1) We have obtained a better MDL score while using exactly the same termination condition for both algorithms. 2) Our approach identifies the number of components which were used to generate the underlying data more often than the EM algorithm.
An Online Platform for Web APIs and Service Mashups (2008)

On the newly programmable Web, mashups are flourishing. Designers create mashups by combining components of existing Web sites and applications. Although rapid mashup proliferation offers many opportunities, a lack of standarization and compatibility offers considerable challenges. IBM Sharable Code is an online service platform for developing and sharing situational Web 2.0 applications and mashups. The platform is based on an innovative domain-specific language that streamlines and standardizes the development and deployment of applications consuming and exposing Web APIs. Parts of the DSL and the resulting applications and mashups can be shared and reused by members of the IBM Sharable Code community. In this article, the authors offer an overview of the platform's architecture and the DSL language at its core.
Neutral Statements (1964)

Journal Article Neutral Statements Get access A. Phillips A. Phillips Search for other works by this author on: Oxford Academic Google Scholar Analysis, Volume 24, Issue 3, January 1964, Pages 68–72, https://doi.org/10.1093/analys/24.3.68 Published: 01 January 1964
Functional single-cell analyses: flow cytometry and cell sorting of microbial populations and communities (2010)

The still poorly explored world of microbial functioning is about to be uncovered by a combined application of old and new technologies. Bacteria, especially, are still in the dark with respect to their phylogenetic affiliations as well as their metabolic capabilities and functions. However, with the advent of sophisticated flow cytometric and cell sorting technologies in microbiological labs, there is now the possibility to gain this knowledge at the single-cell level without cumbersome cultivation approaches. Cytometry also facilitates the understanding of physiological diversity in seemingly likewise acting populations. Both individuality and diversity lead to the complex and concerted actions of microbial consortia. This review provides an overview of the state of the art in the field. It deals with the handling of microorganisms from the very beginning (i.e. sampling, and detachment and fixation procedures) and goes on to discuss the pitfalls and problems in analysing cells without any further treatment. If information cannot be gained by specific staining procedures, phylogenetic technologies, transcriptomic and proteomic approaches may be options for achieving advanced insights. All in all, flow cytometry will be a mediator technology to gain a deeper insight into the heterogeneity of populations and the functioning of microbial communities.
Managing the Complexity of Large Free and Open Source Package-Based Software Distributions (2006)

The widespread adoption of free and open source software (FOSS) in many strategic contexts of the information technology society has drawn the attention on the issues regarding how to handle the complexity of assembling and managing a huge number of (packaged) components in a consistent and effective way. FOSS distributions (and in particular GNU/Linux-based ones) have always provided tools for managing the tasks of installing, removing and upgrading the (packaged) components they were made of While these tools provide a (not always effective) way to handle these tasks on the client side, there is still a lack of tools that could help the distribution editors to maintain, on the server side, large and high-quality distributions. In this paper we present our research whose main goal is to fill this gap: we show our approach, the tools we have developed and their application with experimental results. Our contribution provides an effective and automatic way to support distribution editors in handling those issues that were, until now, mostly addressed using ad-hoc tools and manual techniques
A reassessment of cardiac toxicity associated with Taxol. (1993)

Cardiac toxicity was first noted in patients receiving Taxol during continuous cardiac monitoring, which was performed because of the high incidence of serious hypersensitivity reactions noted early in phase I trials. After cardiac events were documented, patients with cardiac disease and those on medications known to alter cardiac conduction were excluded from most trials. The cardiac events reported with Taxol from the initiation of NCI-sponsored clinical trials through August 1992 are summarized. Adverse cardiac events were reviewed in four clinical databases: 1) the Cancer Therapy Evaluation Program's Adverse Drug Reaction database following treatment of more than 3400 patients; 2) all cardiac toxicities in patients on GOG-111 who were randomized to cisplatin plus either Taxol or cyclophosphamide; 3) cardiac toxicity in 198 patients who received 618 courses of Taxol with or without cisplatin during continuous cardiac monitoring; and 4) cardiac toxicities reported for the first 696 patients on NCI TRC-9103 for ovarian cancer. Published reports of studies of taxine's cardiac effects, and of cardiac toxicity associated with yew poisoning, Cremophor EL, and H1 and H2 antagonists, are also reviewed. In patients without significant cardiac risk factors, asymptomatic sinus bradycardia is frequent (approximately 30%). Heart block and conduction abnormalities occur infrequently and are often asymptomatic. The casual relationship of Taxol to atrial and ventricular arrhythmias and cardiac ischemia is less clear because many patients had other conditions known to be associated with cardiac events. Nevertheless, the incidence of serious cardiac events was low. Routine cardiac monitoring is not required for patients without risk factors. There are, however, insufficient data to make treatment recommendations for patients with cardiac disease and those taking medications that alter cardiac conduction. To maximize patient safety and the clinical database, physicians who administer Taxol should continue to be alert to potential cardiac toxicities associated with Taxol.
Detection of T-cell receptor gamma chain V gene rearrangements using the polymerase chain reaction: application to the study of clonal disease cells in acute lymphoblastic leukemia (1991)

This report describes the development and characterization of a method for the amplification of rearranged V-J segments of the human T-cell receptor gamma chain (TCRG) locus using an adaptation of the polymerase chain reaction (PCR) technique. The technique uses a single pair of 'consensus' primers to amplify rearrangements involving the V gamma I subgroup genes, which are common in malignant cells from acute lymphoblastic leukemia (ALL) patients. Using this method we were able to detect rearrangements in the TCRG locus in disease cells from patients with T-cell ALL (12 of 12), common ALL (10 of 14), and Null cell ALL (2 of 2) at presentation. Monoallelic and biallelic rearrangements involving V gamma I subgroup genes were identified by restriction analysis of PCR products from DNA samples from a T-cell leukemic cell line, T-cell clones, and disease cells from patients with ALL of T-and B-cell lineage at presentation. These results confirmed the presence of cell clones within the presentation samples and, in one case, confirmed the persistence of the original malignant cell clone at relapse. This is a rapid and specific method for the detection and characterization of rearrangements of the TCRG locus without recourse to Southern blotting. Therefore, the PCR technique described herein can provide the basis for the study of clonal evolution and minimal residual disease on a high proportion of patients with ALL.
Electrodeposited Nanostructured CoFe2O4 for Overall Water Splitting and Supercapacitor Applications (2019)

To contribute to solving global energy problems, a multifunctional CoFe2O4 spinel was synthesized and used as a catalyst for overall water splitting and as an electrode material for supercapacitors. The ultra-fast one-step electrodeposition of CoFe2O4 over conducting substrates provides an economic pathway to high-performance energy devices. Electrodeposited CoFe2O4 on Ni-foam showed a low overpotential of 270 mV and a Tafel slope of 31 mV/dec. The results indicated a higher conductivity for electrodeposited compared with dip-coated CoFe2O4 with enhanced device performance. Moreover, bending and chronoamperometry studies suggest excellent durability of the catalytic electrode for long-term use. The energy storage behavior of CoFe2O4 showed high specific capacitance of 768 F/g at a current density of 0.5 A/g and maintained about 80% retention after 10,000 cycles. These results demonstrate the competitiveness and multifunctional applicability of the CoFe2O4 spinel to be used for energy generation and storage devices.
HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells (2009)

By a small modification in the core structure of the previously reported series of HIV-1 protease inhibitors that encompasses a tertiary alcohol as part of the transition-state mimicking scaffold, up to 56 times more potent compounds were obtained exhibiting EC(50) values down to 3 nM. Three of the inhibitors also displayed excellent activity against selected resistant isolates of HIV-1. The synthesis of 25 new and optically pure HIV-1 protease inhibitors is reported, along with methods for elongation of the inhibitor P1' side chain using microwave-accelerated, palladium-catalyzed cross-coupling reactions, the biological evaluation, and X-ray data obtained from one of the most potent analogues cocrystallized with both the wild type and the L63P, V82T, I84 V mutant of the HIV-1 protease.
Le Maître westphalien de 1473: De Soest à Nelahozeves (1992)

info:eu-repo/semantics/published
Low-Power, Low-Phase Noise SiGe HBT Static Frequency Divider Topologies up to 100 GHz (2006)

Static 2:1 frequency dividers with different latch configurations were designed and fabricated in two SiGe HBT technologies. The self-oscillation and maximum operation frequency are found to be correlated with the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MAX</sub> but not with the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> of the technology. A self-oscillation frequency of 77 GHz, the highest among static dividers in SiGe HBT technology, is achieved with the lowest power consumption of 122 mW from 3.3 V supply. Phase noise measurements of the 100-GHz input and 50-GHz output signals indicate ideal behavior with no measurable noise contribution from the divider. All fabricated dividers feature an integrated single-ended-to-differential transformer for ease of testing, yet broadband 20 GHz-100 GHz operation is maintained
Cloning of a Phosphate-Regulated Hemolysin Gene (Phospholipase C) from<i>Pseudomonas aeruginosa</i> (1982)

Phospholipase C (heat-labile hemolysin) of Pseudomonas aeruginosa is a phosphate (P(i))-regulated extracellular protein which may be a significant virulence factor of this organism. The gene for this hemolytic enzyme was cloned on a 4.1-megadalton (Mdal) fragment from a BamHI digest of P. aeruginosa PAO1 genomic DNA and was inserted into the BamHI sites of the multicopy Escherichia coli(pBR322) and P. aeruginosa(pMW79) vectors. The E. coli and P. aeruginosa recombinant plasmids were designated pGV26 and pVB81, respectively. A restriction map of the 4.1-Mdal fragment from pGV26 was constructed, using double and single digestions with BamHI and EcoRI and several different restriction enzymes. Based on information from this map, a 2.4-Mdal BamHI/BglII fragment containing the gene for phospholipase C was subcloned to pBR322. The hybrid plasmids pGV26 and pVB81 direct the synthesis of enzymatically active phospholipase C, which is also hemolytic. The plasmid-directed synthesis of phospholipase C in E. coli or P. aeruginosa is not repressible by P(i) as is the chromosomally directed synthesis in P. aeruginosa. Data are presented which suggest that the synthesis of phospholipase C from pGV26 and pVB81 is directed from the tetracycline resistance gene promoter. The level of enzyme activity produced by E. coli(pGV26) is slightly higher than the levels produced by P. aeruginosa(pMW79) under repressed conditions. In contrast, the levels produced by P. aeruginosa(pVB81) are at least 600-fold higher than the levels produced by P. aeruginosa(pMW79) under repressed conditions and approximately 20-fold higher than those produced by P. aeruginosa(pMW79) under derepressed conditions. The majority (85%) of the enzyme produced by E. coli(pGV26) remained cell associated, whereas >95% of the enzyme produced by P. aeruginosa(pVB81) was extracellular. Analysis of extracellular proteins from cultures of P. aeruginosa(pMW79) and P. aeruginosa(pVB81) by high-performance liquid chromotography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed that the phospholipase C gene was cloned intact, and it is likely that several additional genes were cloned on the 4.1-Mdal fragment of DNA. It was also found that some of these genes encode proteins which are the same molecular weight as some previously described P(i)-repressible proteins of P. aeruginosa. The existence of a P(i) regulon of P. aeruginosa is proposed. It is likely that one of these genes also regulates the level of pyocyanin production by P. aeruginosa and that one or more play a role in transport or binding of P(i). The availability of the hybrid plasmids described herein will be useful in further studies on the role of this hemolysin in the virulence of P. aeruginosa and in the study of the genetics and physiology of P(i)-regulated proteins.
BGP Protocol Analysis (1991)

This report summarizes the key feature of BGP, and analyzes the
protocol with respect to scaling and performance. This memo provides
information for the Internet community. It does not specify an
Internet standard.
I.—PROFESSOR AYER ON THE PROBLEM OF KNOWLEDGE (1958)

I.—PROFESSOR AYER ON THE PROBLEM OF KNOWLEDGE Get access H. H. PRICE H. H. PRICE Oxford Search for other works by this author on: Oxford Academic Google Scholar Mind, Volume LXVII, Issue 268, October 1958, Pages 433–464, https://doi.org/10.1093/mind/LXVII.268.433 Published: 01 October 1958
Historisch-politische Bildungsarbeit für die Polizei am authentischen Ort (2008)

Im letzten Jahrzehnt hätte man leicht den Eindruck gewinnen können: Polizeigeschichte sei eine Erfolgsgeschichte. Innenministerien, agile Polizeipräsidenten und Initiativen von Interessierten, die die Modernität ihres Berufstandes deutlich machen möchten, fördern gleichzeitig Buch-, Dokumentations- Ausstellungsprojekte in Köln, Wuppertal, Bonn, Recklinghausen, Mönchengladbach, Hamm und Düsseldorf und inzwischen auch in anderen Bundesländern.1 Polizeigeschichtliche Sammler innerhalb der Behörden, früher von ihrem Umfeld eher als Exoten wahrgenommen, erhielten über diese Projekte eine positive Resonanz und höhere Reputation. Mit dieser Entwicklung scheint die Form der berufsorientierten, erfahrungsgeschichtlichen Selbstvergewisserung in einer neuen Qualität angekommen zu sein. Täuscht dieser Eindruck? Oder ist dies nur eine polizeihistorische Fata Morgana derjenigen, die sich in der ‘Erkenntniswüste’ an einigen Oasen die Lage schönreden? In jedem Fall ist die selbstkritische historische Analyse des eigenen Berufstandes bundesweit eher die Ausnahme, denn der Regelfall. Sollte dies grundlegend geändert werden, mit welchen Methoden wäre es sinnvoll und wie erreicht diese historisch-politische Anstrengung auch die Menschen, die in Uniform ihren gesellschaftlichen Auftrag ausüben sollen?
Implementing TURF analysis through binary linear programming (2012)

This paper introduces the approach of using Total Unduplicated Reach and Frequency analysis (TURF) to design a product line through a binary linear programming model. This improves the efficiency of the search for the solution to the problem compared to the algorithms that have been used to date. The results obtained through our exact algorithm are presented, and this method shows to be extremely efficient both in obtaining optimal solutions and in computing time for very large instances of the problem at hand. Furthermore, the proposed technique enables the model to be improved in order to overcome the main drawbacks presented by TURF analysis in practice.