gebhart/patrepeval huggingface dataset:
Comparative Transcriptome and Secretome Analysis of Wood Decay Fungi<i>Postia placenta</i>and<i>Phanerochaete chrysosporium</i> (2010)

Cellulose degradation by brown rot fungi, such as Postia placenta, is poorly understood relative to the phylogenetically related white rot basidiomycete, Phanerochaete chrysosporium. To elucidate the number, structure, and regulation of genes involved in lignocellulosic cell wall attack, secretome and transcriptome analyses were performed on both wood decay fungi cultured for 5 days in media containing ball-milled aspen or glucose as the sole carbon source. Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), a total of 67 and 79 proteins were identified in the extracellular fluids of P. placenta and P. chrysosporium cultures, respectively. Viewed together with transcript profiles, P. chrysosporium employs an array of extracellular glycosyl hydrolases to simultaneously attack cellulose and hemicelluloses. In contrast, under these same conditions, P. placenta secretes an array of hemicellulases but few potential cellulases. The two species display distinct expression patterns for oxidoreductase-encoding genes. In P. placenta, these patterns are consistent with an extracellular Fenton system and include the upregulation of genes involved in iron acquisition, in the synthesis of low-molecular-weight quinones, and possibly in redox cycling reactions.
LIMBO/VTK: A Tool for Rapid Tele-Immersive Visualization (1998)

This &quot;Late Breaking Hot Topic Paper&quot; describes LIMBO/VTK a tool that allows developers to quickly build collaborative visualization applications for CAVE, ImmersaDesk as well as desktop workstations. LIMBO/VTK is based on two broadly used technologies: CAVERNsoft, a library for supporting collaborative Virtual Reality; and the Visualization Toolkit, an extensive library for supporting 3D graphics and visualization. Keywords: Virtual Reality, VTK, VR, Collaborative, Distributive, CAVE, CAVERN 1 Introduction We define the term Tele-Immersion as the integration of audio and video conferencing with collaborative virtual reality (VR) in the context of data-mining and significant computation. When participants are tele-immersed, they are able to see and interact with each other in a shared environment. This environment persists even when all the participants have left. The environment may control supercomputing computations, query databases autonomously and gather the results for visualiza...
Sibship size and self‐reported inhalant allergy among adult women (1997)

Although it is not possible to determine whether brothers specifically, or unlike-sex siblings in general, are inversely associated with inhalant allergy, these findings are consistent with the hypothesis that patterns of sibling interaction within young families influence the risk of future aeroallergen sensitization.
Targeting human immunodeficiency virus type 1 with antibodies derived from patients with connective tissue disease (2006)

During the budding process, human immunodeficiency virus (HIV) acquires several cellular proteins from the host. Thus, antibodies against self antigens found in sera patients with autoimmune disorders may cross react with host-derived or the HIV-specific proteins gp120 and gp41 on the viral envelope and probably neutralize HIV infection. To verify this hypothesis, 88 sera from HIV negative patients suffering from systemic lupus erythematosus (SLE) and other autoimmune disorders were analysed for cross reacting antibodies against HIV-1 by Western blot and FACS analysis indicating that antibodies cross-react with epitopes expressed on HIV infected or non-infected cells. Virus capture assays revealed that HIV-1(IIIB) was directly recognized by 60% of sera from patients with autoimmune disorders. Sera were also tested in HIV neutralization assays with stimulated T cells. Reduction of the viral load by patient sera correlated with their reactivity in Western blot analysis. Complement further enhanced the reduction of viral titres, although no complement-mediated lysis was observed. These data suggest a possible protective role of auto-antibodies against HIV infection in lupus patients.
Factors which affect the gelling characteristics of aluminium soaps (1950)

Abstract Three methods of making aluminium soaps are described, and one, the 'metathetic reaction between a sodium soap solution and an aluminium salt solution, is discussed in detail. The effect of variations in manufacturing technique upon the gelling characteristics of the product is considered. Recent work by various investigators on the structure of aluminium soaps is reviewed, particularly in relation to the effect of structure and peptizers upon the gelling property in hydrocarbon solvents. Mention is made of the more important methods of moisture determination and results obtained by the use of the Karl Fischer reagent are quoted.
Effects of Plasma from Acute-on-Chronic Liver Failure Patients on Immortalized Human Hepatocytes in vitro (2011)

Although the toxic effects of plasma from acute-on-chronic liver failure patients should not be ignored, HepLL cells can maintain their function, when exposed to AoCLF plasma, for at least 24h and could be used as a suitable cell source for a bioartificial liver support system.
Yolk Testosterone Stimulates Growth and Immunity in House Finch Chicks (2006)

Female birds deposit variable amounts of androgens, such as testosterone, into the yolks of their eggs. Evidence suggests that yolk androgens play an important role in the determination of offspring phenotype. While androgens are generally regarded as anabolic and immunosuppressive, studies of the behavioral and physiological effects of yolk androgens on offspring of several avian species have been conflicting, leaving the adaptive significance associated with deposition patterns of yolk androgens unclear. We injected either a physiological dose of testosterone or a control vehicle into house finch (Carpodacus mexicanus) eggs and examined the effects of these injections on offspring growth and immunity. Two days after hatching, nestlings from eggs treated with testosterone were significantly larger than nestlings from eggs treated with a control injection, suggesting a stimulatory effect of yolk androgens in early development. By 8 d after hatching, however, this effect disappeared, and chicks from the two treatment groups were similar in size. Nestlings in the testosterone treatment group showed a significantly larger swelling response to phytohemagglutinin than control nestlings 15 d after hatching, which is close to fledging. Overall, our observations show that when food resources are abundant, testosterone stimulates both early growth and immunity in developing house finches.
AdASDiM: application of adaptive control technique to diabetic management (2002)

Describes the software implementation and related issues for the validation of a model reference adaptive system for simulation and optimization of insulin therapy in diabetics. The advisor, denoted AdASDiM, can operate with sparse (3-5 times a day) blood glucose measurements. Due to its adaptivity, it is able to handle the individual differences and changes in the carbohydrate metabolic systems of the patients. Also, the proposed scheme makes use of the knowledge of the time and quantity of future meals and insulin injections.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Synthesis and Photoisomerization Properties of Polynorbornenes with Azobenzene Chromophores (2002)

We successfully synthesized the addition-type polynorbonenes (PNB) exhibiting photochromic properties and excellent thermal stability. Three norbornene-based monomers with different azobenzene moiety (R=NO2, H,OCH3) were synthesized by transesterification method. The corresponding PNB copolymers were synthesized by transition metal-catalyzed addition polymerization method, and characterized by GPC, UV-Vis spectroscopy, NMR, and thermal analysis. For comparison of the photochromic properties depending on the rigidity of polymer backbone, we prepared the polymethylmethacrylate (PMMA) copolymer with the corresponding azobenzene moiety. We investigated the photoisomerization behavior by means of optical muitichannel analyzer with Xe lamp as well as real-time UV-Vis spectroscopy with high-pressure mercury lamp. Among three PNB copolymers, a polymer with azobenzene (R=H) was the most adaptable for observation of photoisomerization behavior. It was found that the rate of photoisomerization and relaxation depended on the structure of azobenzene chromophore, rather than that of polymer backbone.
Developing a novel force forecasting technique for early prediction of critical events in robotics (2020)

Safety critical events in robotic applications can often be characterized by forces between the robot end-effector and the environment. One application in which safe interaction between the robot and environment is critical is in the area of medical robots. In this paper, we propose a novel Compact Form Dynamic Linearization Model-Free Prediction (CFDL-MFP) technique to predict future values of any time-series sensor data, such as interaction forces. Existing time series forecasting methods have high computational times which motivates the development of a novel technique. Using Autoregressive Integrated Moving Average (ARIMA) forecasting as benchmark, the performance of the proposed model was evaluated in terms of accuracy, computation efficiency, and stability on various force profiles. The proposed algorithm was 11% more accurate than ARIMA and maximum computation time of CFDL-MFP was 4ms, compared to ARIMA (7390ms). Furthermore, we evaluate the model in the special case of predicting needle buckling events, before they occur, by using only axial force and needle-tip position data. The model was evaluated experimentally for robustness with steerable needle insertions into different tissues including gelatin and biological tissue. For a needle insertion velocity of 2.5mm/s, the proposed algorithm was able to predict needle buckling 2.03s sooner than human detections. In biological tissue, no false positive or false negative buckling detections occurred and the rates were low in artificial tissue. The proposed forecasting model can be used to ensure safe robot interactions with delicate environments by predicting adverse force-based events before they occur.
Adding reality to the virtual (2002)

Distributed interactive simulation provides an environment for realistic participation in virtual worlds. Humans interact with the virtual world through interface devices such as switches and knobs, keyboards and mice, touch screens and data gloves. The time has come for the seamless integration of these physical, real-world human interface devices with the systems that generate and display the virtual environments. The merging of these two areas will result in virtual world experiences more realistic than any available today.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Urban infrastructures and sustainable social practices (2005)

Click to increase image sizeClick to decrease image size Acknowledgments Special thanks to the organizers and participants of the International Summer Academy on Technology Studies 2004 in Deutschlandsberg, Austria—especially to Peter Wilding and Harald Rohracher—for their critical questions that helped me make the argument more robust. I am also grateful for the comments of the anonymous reviewers.
4-ansa-Metallocene complexes: synthesis of 1,1,4,4-tetramethyl-1,4-disilabutylene-bridged titanocene, zirconocene, and hafnocene derivatives (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT4-ansa-Metallocene complexes: synthesis of 1,1,4,4-tetramethyl-1,4-disilabutylene-bridged titanocene, zirconocene, and hafnocene derivativesHeinrich Lang and Dietmar SeyferthCite this: Organometallics 1991, 10, 1, 347–349Publication Date (Print):January 1, 1991Publication History Published online1 May 2002Published inissue 1 January 1991https://doi.org/10.1021/om00047a071Request reuse permissionsArticle Views113Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (436 KB) Get e-Alertsclose Get e-Alerts
The Importance of Spin Polarization in Electronic Substituent Effects of the Zero-Field EPR <i>D</i> Parameter in 1,3-Diarylcyclopentane-1,3-diyl Triplet Diradicals (1999)

The zero-field-splitting D parameter of 11 meta,para-disubstituted 1,3-diarylcyclopentane-1,3-diyl triplet diradicals has been determined in a 2-MTHF glass matrix at 77 K by EPR spectroscopy. The experimental ΔDexp value, conveniently defined as DH − DX, is a sensitive function of the delocalizing property of the X substituent on the phenyl ring. In contrast to the previously observed additivity for a large variety of para and meta substituents (cf. Adam, W.; Harrer, H. M.; Kita, F.; Nau, W. M. Adv. Photochem. 1998, 24, 205−254), such a simple relation no longer upholds for meta,para disubstitution. For the latter, the higher degree of spin delocalization is accounted for in terms of spin polarization and electronic field effects. For the first time also the increased spin density at the cumyl position caused by meta substituents has been satisfactorily explained by means of spin polarization. The spin density distribution in the cumyl radicals, computed by density functional theory (B3LYP/6-31g*), substantiate these experimental findings.
Chiral [16O, 17O, 18O]phosphate monoesters. 1. Asymmetric synthesis and stereochemical analysis of [1(R)-16O, 17O, 18O]phospho-(S)-propane-1,2-diol (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChiral [16O, 17O, 18O]phosphate monoesters. 1. Asymmetric synthesis and stereochemical analysis of [1(R)-16O, 17O, 18O]phospho-(S)-propane-1,2-diolSteven J. Abbott, Stephen R. Jones, Steven A. Weinman, and Jeremy R. KnowlesCite this: J. Am. Chem. Soc. 1978, 100, 8, 2558–2560Publication Date (Print):April 1, 1978Publication History Published online1 May 2002Published inissue 1 April 1978https://pubs.acs.org/doi/10.1021/ja00476a055https://doi.org/10.1021/ja00476a055research-articleACS PublicationsRequest reuse permissionsArticle Views180Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Desktop aligner for fabrication of multilayer microfluidic devices (2015)

Multilayer assembly is a commonly used technique to construct multilayer polydimethylsiloxane (PDMS)-based microfluidic devices with complex 3D architecture and connectivity for large-scale microfluidic integration. Accurate alignment of structure features on different PDMS layers before their permanent bonding is critical in determining the yield and quality of assembled multilayer microfluidic devices. Herein, we report a custom-built desktop aligner capable of both local and global alignments of PDMS layers covering a broad size range. Two digital microscopes were incorporated into the aligner design to allow accurate global alignment of PDMS structures up to 4 in. in diameter. Both local and global alignment accuracies of the desktop aligner were determined to be about 20 μm cm(-1). To demonstrate its utility for fabrication of integrated multilayer PDMS microfluidic devices, we applied the desktop aligner to achieve accurate alignment of different functional PDMS layers in multilayer microfluidics including an organs-on-chips device as well as a microfluidic device integrated with vertical passages connecting channels located in different PDMS layers. Owing to its convenient operation, high accuracy, low cost, light weight, and portability, the desktop aligner is useful for microfluidic researchers to achieve rapid and accurate alignment for generating multilayer PDMS microfluidic devices.
A Human Putative Lymphocyte G <sub>0</sub> /G <sub>1</sub> Switch Gene Containing a CpG-Rich Island Encodes a Small Basic Protein with the Potential to Be Phosphorylated (1991)

Genes actively involved in the G0/G1 switch (G0S genes) may be differentially expressed during the lectin-induced switch of lymphocytes from the G0 to the G1 phases of the cell cycle. This paper presents studies of G0S2, a member of a set of putative G0S genes, for which cDNAs were cloned and selected on the basis of differential cDNA hybridization. G0S2 mRNA increases transiently within 1-2 hr of the addition of lectin or cycloheximide to cultured blood mononuclear cells. Comparison of a nearly full-length cDNA sequence with the corresponding genomic sequence reveals one small intron and an open reading frame in the second exon. The derived 103-amino-acid basic protein has two potential alpha-helical domains separated by a hydrophobic region with the potential to generate turns and assume a beta-sheet conformation. Consistent with involvement in the G0/G1 switch, the protein contains potential sites for phosphorylation by protein kinase C and casein kinase II. The gene contains a CpG-rich island suggesting expression in the germ line. An upstream segment contains tandem dinucleotide repeats (CT)19/(CA)16. There is a suitably located TATA box, but potential sites for CCAAT-box binding factors are far upstream, embedded in a 42-nucleotide repeat element. Potential sites for transcription factors AP1, AP2, and AP3 are consistent with rapid transcriptional activation in response to inducing agents.
The impact of information technology on energy consumption and carbon emissions (2015)

In this article the authors evaluate the impact of different sectors of information and communication technologies (ICT) on energy consumption and CO2 emissions. ICT is understood to cover computer and peripheral equipment including local area networks, telecommunication equipment and networks, and data centers.
Biochemical characterization of <scp>LR</scp>769, a new recombinant factor VIIa bypassing agent produced in the milk of transgenic rabbits (2017)

The innovative expression system used to produce LR769 yields a new safe and effective rhFVIIa for the treatment of haemophilia A or B patients with inhibitors.
Relative bioavailability in man of noscapine administered in lozenges and mixture. (1992)

The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mixture. The bioavailability of noscapine after administration in lozenges was significantly higher than that after administration of the drug as a mixture. It is concluded that the lozenges containing noscapine base may be a valuable alternative to the conventional noscapine hydrochloride mixture.
Friedel-Crafts alkylation of anisole and its comparison with toluene. Predominant ortho-para substitution under kinetic conditions and the effect of thermodynamic isomerizations (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFriedel-Crafts alkylation of anisole and its comparison with toluene. Predominant ortho-para substitution under kinetic conditions and the effect of thermodynamic isomerizationsGeorge A. Olah, Judith A. Olah, and Toshiyuki OhyamaCite this: J. Am. Chem. Soc. 1984, 106, 18, 5284–5290Publication Date (Print):September 1, 1984Publication History Published online1 May 2002Published inissue 1 September 1984https://pubs.acs.org/doi/10.1021/ja00330a042https://doi.org/10.1021/ja00330a042research-articleACS PublicationsRequest reuse permissionsArticle Views2637Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparison of protein synthesis and degradation in incubated and perfused muscle (1983)

Rates of muscle protein synthesis and degradation measured in the perfused hindquarter were compared with those in incubated epitrochlearis muscles. With fed or starved mature rats, results without insulin treatment were identical. With insulin treatment, protein synthesis in perfused hindquarters was greater, though protein degradation was the same. Thus rates of muscle protein degradation estimated by these two methods in vitro correspond closely.