gebhart/patrepeval huggingface dataset:
A Robust Baseline and Reference Modification and Acquisition Algorithm for Accurate THz Imaging (2017)

This paper reports an accurate baseline and reference modification and acquisition algorithm for terahertz (THz) reflection measurements. The algorithm solves the spatial phase variation problem, which is a major accuracy limitation of THz reflection imaging. It also overcomes the sampling error problem without taking multiple measurements by utilizing two-dimensional data fitting. The algorithm records the spatial information and the laser power status as a database to precisely modify the baseline and reference in a measurement, providing a simple, efficient, and accurate real-time baseline and reference acquisition method. The experimental results show that the algorithm significantly improves the accuracy of the extracted optical properties of the sample with only half of the time required in a traditional THz imaging by avoiding additional baseline and reference measurements. The strong robustness of the algorithm is also proved by the experiment, giving a stable performance against laser power fluctuations.
Isolation, Purification and Partial Characterization of Novel Fluorophores from aging Human Insoluble Collagen-Rich Tissue (1989)

Collagen undergoes progressive browning with aging and diabetes characterized by yellowing, fluorescence and crosslinking, the cause of which remains unelucidated. As an initial step towards understanding the mechanism(s) of insolubilization of collagen in aging, the major fluorophores/chromophores from the insoluble fraction of human dura mater were isolated and their spectroscopic properties were characterized. High molecular weight tryptic peptides of insoluble collagen were cleaved by sequential enzymatic digestion followed by separation into high (HMW) and low molecular weight (LMW) fractions by gel filtration chromatography. LMW was further separated by paper and reverse phase chromatography (HPLC). Two fluorescent peaks, nicknamed P and M, were obtained from LMW which had UV maxima at 325 and 350 nm and excitation/fluorescence maxima at 335/385 and 360/460 nm, respectively. Fluorophore M was borohydride reducible and unstable to acid-hydrolysis, while P remained unaffected. Large quantities of fluorophore M and pyridinoline were found in the highly crosslinked HMW fraction remaining following exhaustive proteolytic digestion. Fluorophore P and M were the major fluorophores recovered from the tryptic digest of insoluble dura mater. Fluorescence spectra of M suggest an iminopropene type of configuration which could result from nonenzymatic browning of collagen with, e.g., glucose or malonyldialdehyde, as a result of lipid peroxidation. Spectroscopic and chemical properties of fluorophore P were reminiscent but not identical with those of pyridinium crosslinks. Structure elucidation of these fluorophores is expected to provide important insight into the aging processes of the extracellular matrix.
Ask Jack: summer jobs and job skills (1996)

article Ask Jack: summer jobs and job skills Share on Author: Jack Wilson View Profile Authors Info & Claims XRDS: Crossroads, The ACM Magazine for StudentsVolume 3Issue 2December 1996 https://doi.org/10.1145/332132.332142Online:01 November 1996Publication History 0citation85DownloadsMetricsTotal Citations0Total Downloads85Last 12 Months3Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Synthesis of β-, γ-, δ-, ..., ω-Halogenated Ketones and Aldehydes (2010)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTSynthesis of β-, γ-, δ-, ..., ω-Halogenated Ketones and AldehydesBart I. Roman†, Norbert De Kimpe, and Christian V. Stevens*View Author Information Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Gent University, Coupure Links 653, B-9000 Gent, Belgium* To whom correspondence should be addressed. E-mail: [email protected]†Ph.D. fellow of the Fund for Scientific Research Flanders (FWO—Vlaanderen). E-mail: [email protected]. Telephone: +32 (0)9 264 93 79. Fax: +32 9 (0)264 62 21.Cite this: Chem. Rev. 2010, 110, 10, 5914–5988Publication Date (Web):June 30, 2010Publication History Received22 December 2009Published online30 June 2010Published inissue 13 October 2010https://pubs.acs.org/doi/10.1021/cr900409hhttps://doi.org/10.1021/cr900409hreview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views7362Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alcohols,Aldehydes,Anions,Ketones,Reagents Get e-Alerts
Tumor-Localized Ligation of CD3 and CD28 with Systemic Regulatory T-Cell Depletion Induces Potent Innate and Adaptive Antitumor Responses (2009)

Tumor-located ligation of CD3 and CD28 can activate both innate (NKT cells) and adaptive (CD4(+) and CD8(+) T cells) responses to create a tumor-destructive environment to control tumor growth, but modulation of regulatory T cells is necessary to unmask local adaptive antitumor responses.
Some Reaction Safety Aspects of Ruthenium-Catalyzed Allylic Oxidations of Δ-5-Steroids in the Pilot Plant (1998)

The ruthenium-catalyzed allylic oxidation of Δ-5-steroids with tert-butyl hydroperoxide to the corresponding unsaturated ketones was studied. During the scale-up to the pilot plant level, serious safety problems were detected, and the identified runaway potential of this reaction was studied. By modifying the original oxidation procedure, it was possible to establish this reaction safely in the pilot plant at 17-kg scale. Furthermore, the procedure was applied successfully to several other steroids on the laboratory scale.
Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State (2013)

Our report provides evidence demonstrating that markers of cell death and neutrophil extracellular trap formation are independently associated with coronary artery disease, prothrombotic state, and occurrence of adverse cardiac events. These biomarkers could potentially aid in the prediction of cardiovascular risk in patients with chest discomfort.
Study on road damage assessment based on RS and GIS (2010)

After the occurrence of natural disasters, objective and accurate assessment of road damage is the key to emergency rescue. However, in the traditional road damage assessment, the assessment factor and the form of assessment result are single. It can only give an overview of damaged roads, but can't further provide their traffic capacities, which are essential for the disaster relief department. A new approach of road damage assessment is presented in this paper. The damage levels are graded based on the magnitude of actual traffic capacities of post-disaster roads, and the detailed damage information is output at three levels - damage block level, single-road level and region level. The proposed method is applied in the damage assessment of roads in Wenchuan County, China, which was hit by an 8.0-magnitude earthquake. The experimental result shows the validity of this method.
Autologous lymph node cell-derived tumor-specific cytotoxic t-cells for use in adoptive immunotherapy of human melanoma (1988)

The in vitro development of tumor-specific cytotoxic T-cells from draining and tumor-involved lymph nodes obtained from melanoma patients were examined. Fresh draining or tumor-involved lymph node cells (LNC) demonstrate no significant cytotoxic activity against a variety of tumor targets including autologous melanoma. Natural killer cell (NK) activity is very low or absent in all of these specimens. Culture of the cells with irradiated autologous tumor and expansion in recombinant interleukin 2 (rIL-2) results in strong cytotoxicity for autologous tumor cells. The cultured cells are T-cells of mixed CD4 and CD8 phenotypes. Following restimulation with autologous tumor, these lines are capable of becoming specifically cytotoxic for autologous tumor as tested in direct killing and in cold target inhibition studies. The LNC yield from fresh specimens ranges from 1 X 10(7) to more than 1 X 10(9) cells averaging 5 X 10(8) cells. After the cells are cultured, we can achieve up to a 60-fold or more increase in cell numbers, that demonstrate strong cytotoxicity for melanomas. The potential for adoptive immunotherapy using such specifically sensitized cytotoxic T-cells of mixed phenotypes is discussed.
Vegetation index-surface temperature feature space and its application (2002)

Vegetation index and surface temperature are important parameters for describing the characteristics of land cover. More useful information will be created by integrated analysis of the two kinds of data together, which will be helpful for us to find out the main principles of the temporal and spatial variation of land cover/land use. The paper focuses on physical connotation and ecological meaning of the vegetation index-surface temperature feature space, analyzes the temporal variation of different types of land cover in this feature space using NOAA AVHRR remote sensing data, and does much site work on the relationship between water index and winter wheat yield in North China. The following views are set forth and tested based on these data: (1) a large area and long time series of land surface parameters can be retrieved from remotely sensed information; (2) different types of land cover have different characteristics in the vegetation index-surface temperature feature space; (3) water index, which is derived from vegetation index and surface temperature, turns out to be a good indicate of the growing situation of crops.
Comparison of Three Sampling Methods for Estimating Adult Stable Fly (Diptera: Muscidae) Populations (1989)

Sampling of adult stable flies, Stomoxys calcitrans (L.), in cattle feedlots was investigated for 3 yr in southeast Nebraska. Three methods of estimating stable fly populations (front leg counts on cattle, a stanchioned-calf technique, and Alsynite fiber glass traps) were compared at three times of day. Time of sampling significantly affected population estimates in 2 of the 3 yr of the study. The correlation between sampling methods was determined for each sampling time and is discussed.
IN architectures for implementing universal personal telecommunications (1994)

This article focuses on architectures for providing universal personal telecommunications (UPT) service to wireline users. Although UPT services could be provided to users of wireless phones, thereby giving those users personal communication services (PCS), the wireline environment introduces certain important complications. Unlike "smart" cellular phones, which can register themselves and the user automatically, wireline telephones are unable to automatically detect and register a UPT user. UPT therefore includes a manual registration procedure to associate a PTN with the phone where calls will be received or placed. Also, unlike personal communications terminals that are typically used by only one person, wireline phones are likely to be shared among other users. Therefore, the network must keep track of who is using the phone, so it can provide the appropriate telecommunications services. It would be difficult or impossible to implement UPT as a switch-based service. Fortunately, an intelligent network (IN) architecture that is well suited for implementing UPT is being deployed by many local exchange (LECs) and interexchange carriers (IXCs).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Molecular Determinants by Which a Long Chain Toxin from Snake Venom Interacts with the Neuronal α7-Nicotinic Acetylcholine Receptor (2000)

Long chain curarimimetic toxins from snake venom bind with high affinities to both muscular type nicotinic acetylcholine receptors (AChRs) (K(d) in the pm range) and neuronal alpha 7-AChRs (K(d) in the nm range). To understand the molecular basis of this dual function, we submitted alpha-cobratoxin (alpha-Cbtx), a typical long chain curarimimetic toxin, to an extensive mutational analysis. By exploring 36 toxin mutants, we found that Trp-25, Asp-27, Phe-29, Arg-33, Arg-36, and Phe-65 are involved in binding to both neuronal and Torpedo (Antil, S., Servent, D., and Ménez, A. (1999) J. Biol. Chem. 274, 34851-34858) AChRs and that some of them (Trp-25, Asp-27, and Arg-33) have similar binding energy contributions for the two receptors. In contrast, Ala-28, Lys-35, and Cys-26-Cys-30 selectively bind to the alpha 7-AChR, whereas Lys-23 and Lys-49 bind solely to the Torpedo AChR. Therefore, alpha-Cbtx binds to two AChR subtypes using both common and specific residues. Double mutant cycle analyses suggested that Arg-33 in alpha-Cbtx is close to Tyr-187 and Pro-193 in the alpha 7 receptor. Since Arg-33 of another curarimimetic toxin is close to the homologous alpha Tyr-190 of the muscular receptor (Ackermann, E. J., Ang, E. T. H., Kanter, J. R., Tsigelny, I., and Taylor, P. (1998) J. Biol. Chem. 273, 10958-10964), toxin binding probably occurs in homologous regions of neuronal and muscular AChRs. However, no coupling was seen between alpha-Cbtx Arg-33 and alpha 7 receptor Trp-54, Leu-118, and Asp-163, in contrast to what was observed in a homologous situation involving another toxin and a muscular receptor (Osaka, H., Malany, S., Molles, B. E., Sine, S. M., and Taylor, P. (2000) J. Biol. Chem. 275, 5478-5484). Therefore, although occurring in homologous regions, the detailed modes of toxin binding to alpha 7 and muscular receptors are likely to be different. These data offer a molecular basis for the design of toxins with predetermined specificities for various members of the AChR family.
Soluble transferrin mediates targeting of hepatitis B envelope antigen to transferrin receptor and its presentation by activated T cells (1994)

In a previous study, we identified that transferrin receptor (TfR) is the receptor utilized by hepatitis B virus (HBV) to enter T cells. We demonstrated that hepatitis B envelope antigen (HBenvAg) is taken up by activated T cells via TfR, processed in endosomal compartments, and presented on class II molecules to specific CD4+ T cell clones. Herein, we report that binding to soluble ferric Tf by HBenvAg is needed in TfR-mediated endocytosis. Accordingly, presentation of HBenvAg by activated T cells is not observed in serum-free medium and is restored by addition of soluble Tf. Moreover, we provide evidence that pre-S2 and S regions of HBenvAg contain the critical residues for the interaction with soluble Tf. Our data not only explain HBV entry into a variety of host activated cells, but may also help in developing strategies to alter the course of chronic HBV infection.
Teaching heterocyclic chemistry (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTeaching heterocyclic chemistryA. R. Katritzky Cite this: J. Chem. Educ. 1965, 42, 12, 636Publication Date (Print):December 1, 1965Publication History Received3 August 2009Published online1 December 1965Published inissue 1 December 1965https://doi.org/10.1021/ed042p636Request reuse permissionsArticle Views421Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (8 MB) Get e-Alertsclose Get e-Alerts
Efficacy of Plantar Loading Parameters During Gait in Terms of Reliability, Variability, Effect of Gender and Relationship Between Contact Area and Plantar Pressure (2005)

The Pedar in-shoe pressure measurement system can be used reliably to quantify contact area and plantar pressure beneath the midfoot region during the midstance phase of gait. This measurement technique can now be used in risk factor studies designed to identify individuals at risk for injury to the foot, ankle, and other lower extremity structures.
Registered government auditors developing their common body of knowledge and skills (2005)

• the professional has to consist of members • the members of the profession have to practice a servic • the members must be able to master highly specialised at the solving of interdisciplinary problems • the knowledge and skills have to be clearly defined in a and Skills (this is highly critical to demarcate the service other professions) • members must have some kind of moral (ethical) respon profession, and to the public that they serve • the members have to recognise altruistic motives before interests • members must strive to continuously enhance and deve • the profession must have a controlling body that perform • the controlling body’s functions must include the followin formulate and enforce admittance requireme formulate and enforce rules of ethical conduc advance the development and application of advance the broad field of knowledge that is develop its own subculture based on unique • the group has to gain public recognition and acceptance
Space-time signal processing for wireless communications: a survey (2002)

This survey paper reviews space-time signal processing (STP) in mobile wireless communications. Space-time processing refers to manipulating signals that are received at or transmitted from an antenna array so as to improve performance. We focus on antenna arrays deployed at the base stations since such applications are of current practical interest. We first introduce channel and signal models for base station antennas, and present the different structures present in the channel model after sampling and stacking the received signals. We then present single user (SU) and multiple user (MU) space-time processing techniques for the reverse link. Our focus is on blind signal separation, and intersymbol/co-channel interference cancellation. We consider a number of recent advances in batch and adaptive blind space-time processing that show promise in solving these problems.
T-lymphocytes with 7;14 translocations: frequency of occurrence, breakpoints, and clinical and biological significance. (1986)

Among 11,915 consecutive patients and 37 normal controls who had chromosome analysis at the Mayo Clinic between 1978 and 1984, 83 had a single sporadic metaphase with a 7;14 translocation. In 81 of the translocations, the breakpoints were at 14q11 and either 7q34 (type I) or 7p13 (type II): type I translocations occurred in 42 patients, and type II, in 39. The two other translocations had different breakpoints: one was t(7;14)(q11;q32), and the other was t(7;14)(p13;q32). All type I and type II translocations occurred in phytohemagglutinin-stimulated lymphocyte cultures; their combined incidence was 4.88 X 10(-4) per metaphase (81 of 165,991 metaphases) in such cultures. No type I or II translocation was found among 6,713 fibroblast metaphases, 33,463 amniocyte metaphases, or 68,972 bone marrow and unstimulated peripheral blood metaphases. One variant 7;14 translocation occurred in a phytohemagglutinin-stimulated culture, and the other occurred in a fibroblast culture. We did not find a correlation of sporadic 7;14 translocations with any month or season of the year or with patient age or sex. Of the 83 patients, 78 had various clinical disorders, three had ataxia-telangiectasia, one was a normal control, and one was an artificial insemination donor. Follow-up studies on 64 (77%) patients indicate that, to date, none have developed any malignant process subsequent to chromosome analysis. Except for ataxia-telangiectasia, the occurrence of types I and II translocations in lymphocyte cultures may have little, if any, clinical significance. The biological significance of these translocations may be the association of genes in chromosome bands 14q11, 7p13, and 7q34 with the normal physiology of lymphocytes such as the alpha- and beta-chains for T-cell antigen receptor.
Biosensors in Antimicrobial Drug Discovery: Since Biology until Screening Platforms (2015)

Antimicrobial drug resistance is a current public health problem, which is compounded by the misuse of antibiotics in medical practice and the emergence of Multidrug-Resistant (MDR) microorganisms. Therefore it is necessary to develop new anti-infective drugs and implement new methodologies able to establish the Antimicrobial Susceptibility (AST) in field and the point-of-care. In this sense biosensors is a promising technology that can detect MDR strains and small molecules in various samples, these devices have the advantages that can be miniaturized for obtain portability, rapidity, and cost-effectiveness. The aim of this work is to present the applications of biosensors technology in antimicrobial drug discovery, since cell based biosensors and cell culture on chips, considering metabolic interactions of the microbial world and the pharmacological response to be inhibited by compounds with promising activity with the end of design antimicrobial drug screening platforms robust, automatable and reproducible
Highly p-doped epitaxial graphene obtained by fluorine intercalation (2011)

We present a method for decoupling epitaxial graphene grown on SiC(0001) by intercalation of a layer of fluorine at the interface. The fluorine atoms do not enter into a covalent bond with graphene but rather saturate the substrate Si bonds. This configuration of the fluorine atoms induces a remarkably large hole density of p ≈ 4.5×10<sup>13</sup> cm<sup>-2</sup>, equivalent to the location of the Fermi level at 0.79 eV above the Dirac point ED.
Prenatal diagnosis of mos46,X,del(Y)(q11.2)/45,X by cytogenetic and molecular studies with multiplex STR analysis (2004)

The present report demonstrates that molecular analysis using polymorphic microsatellite markers and multiplex PCR is a useful complement to cytogenetic methods for the identification and the characterization of Y-chromosomal deletions.
Corporate Views of the Public InterestCorporate Views of the Public Interest, by SonnenfeldJeffrey A. Boston, Mass.: Auburn Publishing Co., 1981, 285 pp., cloth. (1984)

The article presents a review of the book “Corporate Views of the Public Interest,” by Jeffrey A. Sonnenfeld.