gebhart/patrepeval huggingface dataset:
kBot: Knowledge-Enabled Personalized Chatbot for Asthma Self-Management (2019)

There is a well-recognized need for a shift to proactive asthma care given the impact asthma has on overall healthcare costs. The demand for continuous monitoring of patient's adherence to the medication care plan, assessment of environmental triggers, and management of asthma can be challenging in traditional clinical settings and taxing on clinical professionals. Recent years have seen a robust growth of general purpose conversational systems. However, they lack the capabilities to support applications such an individual's health, which requires the ability to contextualize, learn interactively, and provide the proper hyper-personalization needed to hold meaningful conversations. In this paper, we present kBot, a knowledge-enabled personalized chatbot system designed for health applications and adapted to help pediatric asthmatic patients (age 8 to 15) to better control their asthma. Its core functionalities include continuous monitoring of the patient's medication adherence and tracking of relevant health signals and environment data. kBot takes the form of an Android application with a frontend chat interface capable of conversing in both text and voice, and a backend cloud-based server application that handles data collection, processing, and dialogue management. It achieves contextualization by piecing together domain knowledge from online sources and inputs from our clinical partners. The personalization aspect is derived from patient answering questionnaires and day-to-day conversations. kBOT's preliminary evaluation focused on chatbot quality, technology acceptance, and system usability involved eight asthma clinicians and eight researchers. For both groups, kBot achieved an overall technology acceptance value of greater than 8 on the 11-point Likert scale and a mean System Usability Score (SUS) greater than 80.
Host-guest complexation. 61. C- and Z-shaped ditopic cavitands, their binding characteristics, and monotopic relatives (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHost-guest complexation. 61. C- and Z-shaped ditopic cavitands, their binding characteristics, and monotopic relativesDonald J. Cram, Linda M. Tunstad, and Carolyn B. KnoblerCite this: J. Org. Chem. 1992, 57, 2, 528–535Publication Date (Print):January 1, 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/jo00028a025https://doi.org/10.1021/jo00028a025research-articleACS PublicationsRequest reuse permissionsArticle Views429Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Practical device-independent quantum cryptography via entropy accumulation (2018)

Device-independent cryptography goes beyond conventional quantum cryptography by providing security that holds independently of the quality of the underlying physical devices. Device-independent protocols are based on the quantum phenomena of non-locality and the violation of Bell inequalities. This high level of security could so far only be established under conditions which are not achievable experimentally. Here we present a property of entropy, termed "entropy accumulation", which asserts that the total amount of entropy of a large system is the sum of its parts. We use this property to prove the security of cryptographic protocols, including device-independent quantum key distribution, while achieving essentially optimal parameters. Recent experimental progress, which enabled loophole-free Bell tests, suggests that the achieved parameters are technologically accessible. Our work hence provides the theoretical groundwork for experimental demonstrations of device-independent cryptography.
Hapalosin, a Cyanobacterial Cyclic Depsipeptide with Multidrug-Resistance Reversing Activity (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHapalosin, a Cyanobacterial Cyclic Depsipeptide with Multidrug-Resistance Reversing ActivityKlemens Stratmann, David L. Burgoyne, Richard E. Moore, Gregory M. L. Patterson, and Charles D. SmithCite this: J. Org. Chem. 1994, 59, 24, 7219–7226Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/jo00103a011https://doi.org/10.1021/jo00103a011research-articleACS PublicationsRequest reuse permissionsArticle Views811Altmetric-Citations125LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Book Reviews Gilbert Jenkins, 011 Econoniists' Harrdbook 1986 (London: AppliedScience Publishers, 1981). (1984)

According to its preface. the purpose of the Oii Economists' Hnridhu,ok is "to provide a ready reference for those working both inside and outside the oil and energy industries, especially those concerned with that part of it known as oil economics." For oil economists, such a handbook is invaluable. For professionals in other areas of energy economics, it is also quite worthwhile.
Distribution Analysis of Six Predominant<i>Bacteroides</i>Species in Normal Human Feces Using 16S rDNA-Targeted Species-Specific Primers (2002)

In order to analyze the predominant Bacteroides species in normal human feces, species-specific primer sets for Bacteroides eggerthii , B. fragilis , B. ovatus , B. thetaiotaomicron , B. uniformis and B. vulgatus were designed. Normal human feces were cultured on Bacteroides selective agar (neomycin brilliant green taurocolic acid (NBGT) agar plates). We identified the colonies with the aforementioned species-specific primers. B. vulgatus and B. ovatus were found to be predominant in all volunteers, and B. thetaiotaomicron and B. uniformis varied between volunteers. However, B. fragilis and B. eggerthii were not detected in any volunteers using this culture method. When we used the direct PCR method with extracted bacterial DNA from feces, B. vulgatus and B. ovatus were detected from all samples, and B. thetaiotaomicron , B. uniformis and B. fragilis from four or five out of six samples, but no B. eggerthii was detected. This is the first report that analyzes the predominant Bacteroides species in normal human intestine using a systematic molecular identification method. Keywords: Bacteroides , 16S rRNA, species-specific primer, human, feces.
Data protection regulation and the promotion of health research: getting the balance right (2013)

peer reviewed
Rhenium-Catalyzed Highly Efficient Oxidations of Tertiary Nitrogen Compounds to <i>N</i>-Oxides Using Sodium Percarbonate as Oxygen Source (2006)

Sodium percarbonate was found to be an ideal and efficient oxygen source for the oxidation of tertiary nitrogen compounds to N-oxides in excellent yields in presence of various rhenium-based catalysts under mild reaction conditions.
In vivo validation of CAAS QCA‐3D coronary reconstruction using fusion of angiography and intravascular ultrasound (ANGUS) (2008)

The CAAS QCA-3D system allows 3D reconstruction of human coronary arteries based on biplane angiography. Validation against the ANGUS system showed that both the 3D geometry and lumen areas are highly correlated which makes the CAAS QCA-3D system a promising tool for applications in the catheterization laboratory and opens possibilities for computational fluid dynamics.
RESEARCHES ON HYDANTOINS. XXXV. A NEW METHOD OF SYNTHESIZING GLYCOCYAMIDINE COMPOUNDS, AND THE CONVERSION OF GLYCOCYAMIDINE INTO ISOMERS OF CREATININE. (1915)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRESEARCHES ON HYDANTOINS. XXXV. A NEW METHOD OF SYNTHESIZING GLYCOCYAMIDINE COMPOUNDS, AND THE CONVERSION OF GLYCOCYAMIDINE INTO ISOMERS OF CREATININE.Treat B. Johnson and Ben H. NicoletCite this: J. Am. Chem. Soc. 1915, 37, 10, 2416–2426Publication Date (Print):October 1, 1915Publication History Published online1 May 2002Published inissue 1 October 1915https://pubs.acs.org/doi/10.1021/ja02175a026https://doi.org/10.1021/ja02175a026research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Implantable Cardioverter Defibrillator Lead Complications and Laser Extraction in Children and Young Adults with Congenital Heart Disease: Implications for Implantation and Management (2003)

Young congenital heart disease patients with an ICD are at risk for growth-related lead distortion. The use of a laser sheath is safe and effective for ICD lead extraction in congenital heart disease patients, despite coil adherence and altered anatomy. It may be advisable to avoid dual-coil leads in patients with the potential for future growth.
Tunable replica bits for dynamic variation tolerance in 8T SRAM (2010)

Infrequent dynamic events like V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">CC</sub> droops and temperature changes result in the use of a static V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">CC</sub> guard-band. Measured data on a 16KB 8T array featuring tunable replica bits illustrate the opportunity of eliminating a majority of the static guard-band in memory arrays, resulting in lower operating V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">CC</sub> /power.
Coherent kiloelectronvolt x-rays generated by subcycle optical drivers: a feasibility study (2014)

We theoretically explored the feasibility of high-harmonic generation in the kiloelectronvolt spectral range by optical waveforms of durations progressively shortened from multicycle to subcycle. Our study revealed that subcycle optical pulses offer a clear advantage in generating isolated x-ray attosecond pulses. In combination with their sub-fs optical drivers these pulses will open the route for x-ray attosecond pump-optical attosecond probe experiments, advancing attosecond streaking and attosecond absorption techniques to new realms of investigation of electronic processes.
Nanostructured three-dimensional thin film silicon solar cells with very high efficiency potential (2011)

We report on the experimental realization of amorphous/microcrystalline silicon tandem solar cells (Micromorph) based on our three-dimensional design. An enhancement is reached in the short-circuit current by 40%, with an excellent open-circuit voltage of 1.41V and a fill factor of 72%. We have used nanoholes or microholes dry etched into the ZnO front contact layer. Monte Carlo optical modeling shows that stable efficiency of amorphous silicon p-i-n solar cells in over 12% range is possible. For the Micromorph cells, efficiency over 15% with the thickness of amorphous Si below 200 nm and of microcrystalline Si around 500 nm is possible.
Relative 3-D reconstruction using multiple uncalibrated images (2002)

It is shown how relative 3-D reconstruction for point correspondence of multiple images from uncalibrated cameras can be achieved through reference points. The original contributions with respect to other related works in the field are a direct global method for relative 3-D reconstruction and a geometrical method to select a correct set of reference points among all image points. Experimental results from both simulated and real image sequences are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Coma arousal procedure: A therapeutic intervention in the treatment of head injury (1990)

This study reports on the efficacy of a 'coma arousal procedure'. This procedure involved a programme of vigorous sensory stimulation administered to comatose patients by relatives using Comakits. An experimental group of 12 severely head-injured patients received the coma arousal procedure while a matched control group did not. Total duration of coma and weekly Glasgow Coma Scale Scores were recorded for the two groups. Results indicate that the total duration of coma was significantly shorter and that coma lightened more rapidly for the experimental group.
Multifunctional Yolk−Shell Nanoparticles: A Potential MRI Contrast and Anticancer Agent (2008)

We report a new type of multifunctional nanomaterials, FePt@Fe2O3 yolk-shell nanoparticles, that exhibit high cytotoxicity originated from the FePt yolks and strong MR contrast enhancement resulting from the Fe2O3 shells. Encouraged by the recently observed high cytotoxicity of FePt@CoS2 yolk-shell nanoparticles, we used Fe2O3 to replace CoS2 as the shells to further explore the applications of the yolk-shell nanostructures. The ultralow IC50 value (238 +/- 9 ng of Pt/mL) of FePt@Fe2O3 yolk-shell nanoparticles likely originates from the fact that the slow oxidation and release of FePt yolks increases the cytotoxicity. Moreover, compared with two commercial magnetic resonance imaging (MRI) contrast agents, MION and Sinerem, the FePt@Fe2O3 yolk-shell nanoparticle showed stronger contrast enhancement according to their apparent transverse relaxivity values (r2* = 3.462 (microg/mL)(-1) s(-1)). The bifunctional FePt@Fe2O3 yolk-shell nanoparticles may serve both as an MRI contrast agent and as a potent anticancer drug. This work indicates that these unique yolk-shell nanoparticles may ultimately lead to new designs of multifunctional nanostructures for nanomedicine.
Double external cavity laser diode for DWDM applications (1999)

A balanced dual-wavelength external cavity laser diode operating at 1.3 µm is reported with a side-mode suppression ratio of >35 dB. The construction of this laser is based on a double external cavity using a 1:2 coupler and two different Bragg reflectors photo-written within each channel. Thanks to the photo-written external cavity behaviour, a laser with more than eight channels could be considered.
Accumulation of the angucycline antibiotic rabelomycin after disruption of an oxygenase gene in the jadomycin B biosynthetic gene cluster of Streptomyces venezuelae (1996)

DNA from a region downstream of and overlapping the polyketide synthase (PKS) gene cluster for jadomycin B biosynthesis in Streptomyces venezuelae was cloned and sequenced. Analysis of the nucleotide sequence located one complete ORF (ORF6), an incomplete one representing the 3' region of ORF4 in the PKS cluster, and a second incomplete one (ORF7). The deduced amino acid sequences for ORFs 6 and 7 resemble those of oxygenases. Since a plausible biosynthetic pathway for jadomycin B includes an angular polyketide intermediate that undergoes oxidative ring fission before condensation with an amino acid, we subcloned one of the presumptive oxygenase genes (ORF6) in a segregationally unstable shuttle vector (pHJL400) and disrupted it by inserting the gene for apramycin resistance. Transformation of S. venezuelae with the disruption vector and selection for apramycin resistance gave mutants blocked in jadomycin biosynthesis. Southern hybridization confirmed that gene replacement had occurred. Cultures of the mutants accumulated a metabolite identified by comparison with an authentic sample as rabelomycin, a non-nitrogenous polyketide-derived antibiotic originally isolated from Streptomyces olivaceus.
Role of Prolactin in the Transcription of β‐Casein and 28‐S Ribosomal Genes in the Rabbit Mammary Gland (1980)

Isolated mammary nuclei were incubated in the presence of HgCTP and the neosynthesized RNA was isolated with a SH-Sepharose column. The concentration of beta-casein mRNA and 28-S ribosomal RNA in the neosynthesized RNA fractions was evaluated using [3H]DNA probes complementary to beta-casein mRNA and 28-S rRNA respectively. In the unstimulated pseudopregnant rabbit, the transcription of both genes was easily detectable. Injections of prolactin progressively enhanced the transcription rate of both genes and preferentially the beta-casein gene. A comparison between the transcription rates and the accumulation of the corresponding gene products in the cell revealed that there is a good correlation between these two parameters for the 28-S rRNA gene. By contrast, the acceleration of beta-casein gene transcription by prolactin is unable to account for the simultaneous accumulation of beta-casein mRNA, indicating that prolactin is a potent stabilizer of casein mRNA. Injections of CB154 into lactating rabbits (a drug which suppresses the secretion of prolactin by hypophysis), induced a rapid drop of beta-casein mRNA concentration and a slow decline of beta-casein gene transcription. Simultaneously the drug was responsible for a marked and rapid decrease of 28-S rRNA gene transcription, while the concentration of the rRNA remained elevated. During weaning the transcription of the beta-casein gene and, to a lower degree, the transcripton of the 28-S rRNA gene proceeded more slowly and this phenomenon was accompanied by a progressive decline of the RNA concentrations.
All-glass wafer-level lens technology for array cameras (2014)

We present a novel all-glass wafer-level lens manufacturing technology. Compared to existing wafer-level lens manufacturing technologies, we realize lenses all in glass, which has a number of distinct advantages, including the availability of different glass types with largely varying dispersion for efficient achromatic lens design. Another advantage of all-glass solutions is the ability to dice the lens stack to match the form factor of a rectangular sensor area without compromising the optical performance of the lens, thereby allowing to significantly reducing the footprint of an array camera.
CA 15-3 and Related Mucins as Circulating Markers in Breast Cancer (1999)

In many Western countries breast cancer is the most common malignancy affecting women, the major cause of cancer deaths in women and the major cause of death from any cause in women aged 35-54 years.' By the year 2000, it is estimated that approximately 1 million new cases per year will be diagnosed worldwide. This will represent an increase of 24% for the period 1990--2000, or over 2% per year.' Because of its enormous impact on society, more funding has probably been devoted to research into breast cancer than into any other malignancy. One of the key aims of this research has been to develop biochemical tests for aiding diagnosis, assessing prognosis, predicting likely response to therapy and monitoring patients. Amongst the clinically most useful tests to result from this work have been the assays of oestrogen and progesterone receptors (ER and PR). For over 20 years, tissue-based assays of these two receptors have been in routine use both for predicting hormone dependence of breast cancers and for assessing prognosis.? In addition to ER and PR, many other tissue-based assays have been investigated for use in aiding prognosis. These include the genes and their protein products directly involved in carcinogenesis (e.g. c-oncogenes and tumour suppression genes) and metastasis [e.g. proteases such as urokinase plasminogen activator and cathepsin D (for reviews see references 3 and 4)]. Although some of these new markers (e.g. urokinase plasminogen activator) provide prognostic information that is independent of the traditionally used parameters such as tumour size and nodal status, none is yet in routine clinical use. In contrast to the moderate success with tissue-based markers, attempts to find a sensitive and specific circulating breast cancer marker
Hardware testing for error tolerant multimedia compression based on linear transforms (2006)

In this paper, we propose a system-level error tolerance scheme for systems where a linear transform is combined with quantization. These are key components in multimedia compression systems, e.g., video and image codecs. Using the concept of acceptable degradation, our scheme classifies hardware faults into acceptable and unacceptable faults. We propose analysis techniques that allow us to estimate the faults' impact on compression performance, and in particular on the quality of decoded images/video. We consider as an example the discrete cosine transform (DCT), which is part of a large number of existing image and video compression systems. We propose methods to establish thresholds of acceptable degradation and corresponding testing algorithms for DCT-based systems. Our results for a JPEG encoder using a typical DCT architecture show that over 50% of single stuck-at interconnection faults in one of its 1D DCT modules lead to imperceptible quality degradation in the decoded images, over the complete range of compression rates at which JPEG can operate.