gebhart/patrepeval huggingface dataset:
Evidence for ferroelectric border traps near the SrBi2Ta2O9/Si interface through capacitance–voltage measurement (2000)

A metal–ferroelectric–semiconductor (MFS) structure has been developed by depositing SrBi2Ta2O9 (SBT) films directly on n-type (100) Si by pulsed laser deposition. In the MFS structure, evidence for ferroelectric border traps in the SBT film has been obtained by high-frequency capacitance–voltage (C–V) measurement. When the ramp rate of voltage is higher than 200 mV/s, typical ferroelectric C–V hysteresis loops with the counterclockwise direction are obtained in C–V plots. When the ramp rate is lower than 80 mV/s, the ferroelectric hysteresis loops are replaced by the trap-induced ones with the clockwise direction. This pronounced change results from the fact that more and more border traps in SBT can communicate with the underlying Si. The border-trap density at the ramp rate of 10 mV/s is as high as 1.8×1012 cm−2. Moreover, the width of the hysteresis loops changes linearly with the logarithmic decrease in ramp rate, which is consistent with the ferroelectric border traps communicating with Si by tunneling or a thermally activated process.
Regulation of<i>Arabidopsis</i>shoot apical meristem and lateral organ formation by microRNA<i>miR166g</i>and its<i>AtHD-ZIP</i>target genes (2005)

Plant development is characterized by precise control of gene regulation, leading to the correct spatial and temporal tissue patterning. We have characterized the Arabidopsis jabba-1D (jba-1D) mutant, which displays multiple enlarged shoot meristems, radialized leaves, reduced gynoecia and vascular defects. The jba-1D meristem phenotypes require WUSCHEL (WUS) activity, and correlate with a dramatic increase in WUS expression levels. We demonstrate that the jba-1D phenotypes are caused by over-expression of miR166g, and require the activity of the RNase III helicase DCL1. miR166g over-expression in jba-1D plants affects the transcripts of several class III homeodomain-leucine zipper (AtHD-ZIP) family target genes. The expression of PHABULOSA (PHB), PHAVOLUTA (PHV) and CORONA (CNA) is significantly reduced in a jba-1D background, while REVOLUTA (REV) expression is elevated and ATHB8 is unchanged. In addition, we show that miR166 has a dynamic expression pattern in wild-type and jba-1D embryos. Our analysis demonstrates an indirect role for miRNAs in controlling meristem formation via regulation of WUS expression, and reveals complex regulation of the class III AtHD-ZIP gene family.
Frequency-Tunable Microwave Generation Based on Time-Delayed Optical Combs (2011)

A novel approach to generating a frequency-tunable microwave signal based on time-delayed optical combs is proposed and demonstrated. The fundamental principle is to generate multiple optical combs with identical comb profile, but with each optical comb carried by an optical carrier at a different wavelength. If the optical carriers are spaced with an identical wavelength spacing, the optical combs will be time delayed with an identical time delay after passing through a dispersive fiber. By applying these optical combs to a photodetector, microwave comb lines at the fundamental-order and higher order harmonic frequencies will be generated. For a well-designed time-delay structure, however, the desired microwave harmonic will have the highest output due to constructive interference, while the other harmonics will be suppressed. An analysis is performed, which is verified by a proof-of-concept experiment. A microwave signal that is tunable from 16.8 to 27 GHz is generated. The performance of the generated signal in terms of stability and phase noise is also evaluated.
Hormonal Regulation of Postnatal Growth in Children Born Small for Gestational Age (2006)

Children born small for gestational age (SGA) are at high risk of permanent short stature, with approximately 10% continuing to have stature below the third centile throughout childhood and adolescence and into adulthood. The mechanisms involved in catch-up growth, and those that prevent catch-up growth, are still unknown. To date, no reliable anthropometric or endocrine parameter predictive of postnatal catch-up growth has been identified. However, subtle abnormalities in the growth hormone-insulin-like growth factor axis, the hypothalamic-pituitary-adrenal axis and thyroid function have been described, and a mechanism involving intrauterine programming of hypothalamic-pituitary function has been proposed.
Low‐frequency thermomechanical spectrometry of polymeric materials: Tactic poly(methyl methacrylates) (1977)

Abstract A computerized and automated torsional pendulum has been used to characterize amorphous poly(methyl methacrylates) at about 1 Hz in the temperature sequence 473° → 93° → 473°K. The effects of thermal prehistory, temperature cycling, water content, and tacticity are demonstrated. In particular, a comparison of the out‐of‐phase shear modulus ( G″ ) versus temperature for “syndiotactic,” “atactic,” and “isotactic” polymer specimens shows that the intensity of the glassy‐state β loss peak decreases with increasing isotactic content while the temperature of its location remains the same. Extrapolation suggests that completely isotactic polymer would not display a β loss peak. The shape and location of the G″ data at low temperatures indicate that the basic mechanism of the β process is the same for the three polymer samples and support the validity of the extrapolation. The effect of tacticity is reflected also in the glass transition region; the isotactic sample has its T g about 65°C lower with greater intensity than the syndiotactic polymer.
Synthesis of NH3-SCR Catalyst SAPO-56 with Different Aluminum Sources (2015)

NH3-SCR has become the most popular and successful process of controlling the emission of NOx from coal-fired power plants. Scientists have been always working hard to design a series of new NH3-SCR catalyst to perform an appealing catalytic ability in practical application. Due to equipping with AFX framework structure and certain similar properties with SAPO-34, which has shown a good performance as an NH3-SCR catalysis, SAPO-56 could also have appealing abilities in SCR and realize a effective control of NOx. We synthesis the SAPO-56 with a varies of aluminum sources and with different crystallization times in order to determine the best conditions. The results show that, when taking aluminum hydroxide, pseudo-boehmite or aluminum powder as aluminum source and 4 days as crystallization time, the optimal SAPO-56 crystals could be well synthesized.
Score-CAM: Score-Weighted Visual Explanations for Convolutional Neural Networks (2019)

Recently, increasing attention has been drawn to the internal mechanisms of convolutional neural networks, and the reason why the network makes specific decisions. In this paper, we develop a novel post-hoc visual explanation method called Score-CAM based on class activation mapping. Unlike previous class activation mapping based approaches, Score-CAM gets rid of the dependence on gradients by obtaining the weight of each activation map through its forward passing score on target class, the final result is obtained by a linear combination of weights and activation maps. We demonstrate that Score-CAM achieves better visual performance and fairness for interpreting the decision making process. Our approach outperforms previous methods on both recognition and localization tasks, it also passes the sanity check. We also indicate its application as debugging tools. Official code has been released.
Investigation of a multi-set-point first heat treatment methodology for the silver-sheathed (Bi, Pb)2Sr2Ca2Cu3Ox composite conductor (2002)

A new type of first heat treatment procedure for the silver-sheathed (Bi, Pb)2Sr2Ca2Cu3Ox composite conductor (Ag/Bi-2223) has been investigated. This new procedure consists of using multiple oxygen partial pressure/temperature set point conditions that are systematically varied during the course of the first heat treatment. The present embodiment of this procedure (referred to as thermal slide heat treatment) involves the use of three specific set point conditions (21.0% O2/835 °C, 7.5% O2/825 °C and 4.0% O2/815 °C) appropriately sequenced and tuned to specific time intervals. Application of this procedure as a first heat treatment for powder-in-tube-type Ag/Bi-2223 composite wire specimens was found to produce a minimal amount (<8 area% as seen in cross section views of transverse mounted specimens) of finely divided nonsuperconducting secondary phases in the Bi-2223 filament cores. Also, a direct correlation was observed between the amount of nonsuperconducting secondary phase contained in the Ag/Bi-2223 specimens at the end of the first heat treatment and the performance (in terms of JC) of the fully processed specimen.
Effects of Speed and Limb Dominance on Eccentric and Concentric lsokinetic Testing of the Knee (1988)

This study investigated the effects of speed and limb dominance on torque values and ratios of the quadriceps and hamstrings during both eccentric and concentric exercise. Both knees of 12 males and 13 females, 21-33 years of age, were tested at 30 degrees /sec and 180 degrees /sec on the KIN-COM. Results indicated that: 1) concentric quadriceps torque values and torque/body weight ratios decreased significantly at the higher speed, 2) no significant changes in eccentric quadriceps or eccentric hamstrings torque occurred at the two speeds, 3) no significant differences were demonstrated in the torque values or torque/body weight ratios between dominant and nondominant knees during both concentric and eccentric exercise at both speeds, 4) hamstrings/quadriceps torque ratios increased significantly at the higher speed during concentric exercise, and 5) for males, the hamstrings/quadriceps ratios were significantly greater in the nondominant limb during both concentric and eccentric exercise at both speeds. These findings are important when establishing appropriate and safe rehabilitation goals during isokinetic eccentric activity.J Orthop Sports Phys Ther 1988;10(2):59-65.
Controlling the velocity of ultrashort light pulses in vacuum through spatio-temporal couplings (2017)

Due to their broad spectral width, ultrashort lasers provide new possibilities to shape light beams and control their properties, in particular through the use of spatio-temporal couplings. In this context, we present a theoretical investigation of the linear propagation of ultrashort laser beams that combine temporal chirp and a standard aberration known as longitudinal chromatism. When such beams are focused in a vacuum, or in a linear medium, the interplay of these two effects can be exploited to set the velocity of the resulting intensity peak to arbitrary values within the Rayleigh length, i.e. precisely where laser pulses are generally used. Such beams could find groundbreaking applications in the control of laser-matter interactions, in particular for laser-driven particle acceleration.
A Familial Syndrome of Hypocalcemia with Hypercalciuria Due to Mutations in the Calcium-Sensing Receptor (1996)

Gain-of-function mutations in the calcium-sensing receptor are associated with a familial syndrome of hypocalcemia with hypercalciuria that needs to be distinguished from hypoparathyroidism.
Infectious Respiratory Syncytial Virus (RSV) Effectively Inhibits the Proliferative T Cell Response to Inactivated RSV In Vitro (1992)

The effect of respiratory syncytial virus (RSV) on the cellular immune response of human mononuclear cells in vitro was examined. Inhibition by RSV of the lymphocyte response to phytohemagglutinin in vitro was confirmed using cells from human umbilical cord blood. In addition, RSV significantly inhibited both the proliferative and T cell colony responses of human mononuclear cells to Epstein-Barr virus. An RSV-specific cellular immune response was induced in vitro by stimulation of mononuclear cells from RSV-seropositive donors with beta-propiolactone-inactivated RSV. This RSV-specific response was significantly inhibited by infectious RSV itself, and the inhibition was mediated by an extracellular factor produced by RSV-infected mononuclear cells. A similar inhibition in vivo of the RSV-induced cellular immune response may contribute significantly to delayed recovery from primary infection and to reduced resistance to subsequent infections.
Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic (2008)

B-RAF is frequently mutated in solid tumors, resulting in activation of the MEK/ERK signaling pathway and ultimately tumor cell growth and survival. MEK inhibition in these cells results in cell cycle arrest and cytostasis. Here, we have shown that MEK inhibition also triggers limited apoptosis of human tumor cell lines with B-RAF mutations and that this effect was dependent on upregulation and dephosphorylation of the proapoptotic, Bcl-2 homology 3-only (BH3-only) Bcl-2 family member Bim. However, upregulation of Bim was insufficient for extensive apoptosis and was countered by overexpression of Bcl-2. To overcome apoptotic resistance, we treated the B-RAF mutant cells both with MEK inhibitors and with the BH3 mimetic ABT-737, resulting in profound synergism and extensive tumor cell death. This treatment was successful because of both efficient antagonism of the prosurvival Bcl-2 family member Mcl-1 by Bim and inhibition of Bcl-2 and Bcl-x(L) by ABT-737. Critically, addition of ABT-737 converted the predominantly cytostatic effect of MEK inhibition to a cytotoxic effect, causing long-term tumor regression in mice xenografted with human tumor cell lines. Thus, the therapeutic efficacy of MEK inhibition requires concurrent unleashing of apoptosis by a BH3 mimetic and represents a potent combination treatment for tumors harboring B-RAF mutations.
Mixing enhancement behind a backward-facing step using tabs (2007)

Mixing enhancement behind a backward-facing step is experimentally investigated using multiple tabs located at the edge of the backward-facing step. The Reynolds number is 24000 based on the free-stream velocity and step height with a turbulent boundary layer flow at the inlet. A parametric study is performed to find the optimal tab configuration of minimizing the reattachment length. The parameters of the tab are its height and spanwise width, and the spanwise spacing between two adjacent tabs. For each tab configuration, we measure the reattachment length and wall pressure, and for the optimal configuration the streamwise velocity behind the step. For most tab configurations considered, the reattachment length decreases and turbulence intensity increases at almost all spanwise locations. The reattachment length and wall pressure show significant variations along the spanwise direction. It is found that the tabs introduce strong three-dimensional disturbances to the separating shear layer by producing a pair of counter-rotating streamwise vortices and entrain high momentum fluids into the recirculation region, which greatly enhances mixing behind the backward-facing step.
Participation of the Mouse Implanting Trophoblast in Nitric Oxide Production During Pregnancy1 (2000)

While considerable progress has been made in elucidating nitric oxide (NO) regulatory mechanisms in the later stages of gestation, much less is known about its synthesis and role during embryo implantation. Thus, to evaluate the participation of the trophoblast in the production of NO during this phase, this study focused on NADPH-diaphorase activity and the distribution of NO synthase isoforms (NOS) using immunohistochemistry in pre- and postimplantation mouse embryos in situ and in vitro, as well as on NO production itself, measured as total nitrite, in trophoblast culture supernatants (Griess reaction). No NADPH-diaphorase activity was found in preimplanting embryos except after culturing for at least 48 h, when a few trophoblastic giant cells were positive. Conversely, postimplantation trophoblast cells either lodged into the implantation chamber (in situ) or after culturing (in vitro) showed intense NADPH-diaphorase activity. Also in the postimplantation trophoblast, the endothelial and inducible NOS (eNOS and iNOS) isoforms were immunodetected, under both in situ and in vitro conditions, although in different patterns. Extracts of ectoplacental cone also revealed bands of 135 and 130 kDa on SDS-PAGE that reacted with anti-eNOS and anti-iNOS, respectively, on Western blot. Analysis of the culture supernatant demonstrated that the nitrite concentration was 1) proportional to the number of cultured trophoblast cells, 2) almost completely abolished in the presence of N(omega)-nitro-L-arginine methyl ester, and 3) increased 2-fold in cultures stimulated with gamma-interferon. These results strongly suggest the production of NO from constitutive and inducible isoforms of NOS by the implanting mouse trophoblast. They also emphasize the possibility of the participation of these cells in vasodilatation and angiogenesis, and in cytotoxic mechanisms involved in the intense phagocytosis of injured maternal cells, which occur during the implantation process.
Formation of lateral root meristems is a two-stage process (1995)

In both radish and Arabidopsis, lateral root initiation involves a series of rapid divisions in pericycle cells located on the xylem radius of the root. In Arabidopsis, the number of pericycle cells that divide to form a primordium was estimated to be about 11. To determine the stage at which primordia are able to function as root meristems, primordia of different stages were excised and cultured without added hormones. Under these conditions, primordia that consist of 2 cell layers fail to develop while primordia that consist of at least 3-5 cell layers develop as lateral roots. We hypothesize that meristem formation is a two-step process involving an initial period during which a population of rapidly dividing, approximately isodiametric cells that constitutes the primordium is formed, and a subsequent stage during which meristem organization takes place within the primordium.
Multilevel space vector PWM technique based on phase-shift harmonic suppression (2002)

A new multilevel space vector PWM technique is proposed for high power applications. The technique is developed for H-bridge series-connected multilevel inverters. A phase-shift between space vectors produced by power cells is used for harmonic suppression. As a result, hardware and software implementation is greatly simplified. The phase-shift concept has been verified by simulations and experiments with a two-cell (five-level) series-connected voltage inverter with a space vector PWM. The proposed technique can be easily extended to higher level inverters.
Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma (2015)

The recent finding that MYC-driven cancers are sensitive to inhibition of the DNA damage response (DDR) pathway, prompted us to investigate the role of DDR pathway as therapeutic target in diffuse large B-cell lymphoma (DLBCL), which frequently overexpresses the MYC oncogene. In a preliminary immunohistochemical study conducted on 99 consecutive DLBCL patients, we found that about half of DLBCLs showed constitutive expression of the phosphorylated forms of checkpoint kinases (CHK) and CDC25c, markers of DDR activation, and of phosphorylated histone H2AX (γH2AX), marker of DNA damage and genomic instability. Constitutive γH2AX expression correlated with c-MYC levels and DDR activation, and defined a subset of tumors characterised by poor outcome. Next, we used the CHK inhibitor PF-0477736 as a tool to investigate whether the inhibition of the DDR pathway might represent a novel therapeutic approach in DLBCL. Submicromolar concentrations of PF-0477736 hindered proliferation in DLBCL cell lines with activated DDR pathway. These results were fully recapitulated with a different CHK inhibitor (AZD-7762). Inhibition of checkpoint kinases induced rapid DNA damage accumulation and apoptosis in DLBCL cell lines and primary cells. These data suggest that pharmacologic inhibition of DDR through targeting of CHK kinases may represent a novel therapeutic strategy in DLBCL.
Low power all-optical switching in a nonlinear opticalloop mirror using chalcogenide glass fibre (1996)

All-optical switching is demonstrated using a nonlinear loop mirror containing a low loss As2S3 based fibre module. The gate power is reduced to as little as 0.4 W(peak) using a 4 m long As2S3 fibre. Demultiplexing of a 40 GHz pulse train to 4 GHz is demonstrated.
Bpipe: a tool for running and managing bioinformatics pipelines (2012)

Bpipe is freely available from http://bpipe.org under a BSD License.
Bispectrum analysis of visually evoked potentials (1997)

This article presents results obtained from single-set analysis, and an increase in the SNR is derived and demonstrated by real data. In addition, some aspects of practical signal analysis and detection are discussed. It is concluded that, being a relatively simple method for analyzing biosignals, the bispectrum turns out to be very efficient for the detection of phase-coupled harmonics in background noise. The results obtained so far for steady-state visually evoked potentials suggest that there are nonlinearities of at least seventh order in the conduction and processing of the stimuli. Therefore, future research will be carried out to detect this phenomenon. A necessary condition for using conventional detectors is the whiteness of noise. Since higher-order spectra are used in the analysis of biosignals, an appropriate prewhitening algorithm for higher-order moments needs to be developed.
Technology of Magnetically Driven Accelerators (1985)

The marriage of Induction Linac technology with Nonlinear Magnetic Modulators has produced some unique capabilities. It appears possible to produce electron beams with average currents measured in amperes, at gradients exceeding 1 MeV/meter, and with power efficiencies approaching 50%. A 2 MeV, 5 kA electron accelerator has been constructed at the Lawrence Livermore National Laboratory (LLNL) to demonstrate these concepts and to provide a test facility for high brightness sources. The pulse drive for the accelerator is based on state-of-the-art magnetic pulse compressors with very high peak power capability, repetition rates exceeding a kilohertz and excellent reliability.
Metrology of semiconductor structures using novel Fabry Perot fringe stretching system (2017)

We describe patent pending fiber optic apparatus for measurements of thicknesses and distance employing low resolution spectrometer and etalon. The application of an additional known reference etalon "stretches fringes" and allows us to use Fabry Perot interference to investigate thick samples and large distances which would not be possible when using the low resolution spectrometer alone.
A survey on real-time event detection from the Twitter data stream (2017)

The proliferation of social networking services has resulted in a rapid growth of their user base, spanning across the world. The collective information generated from these online platforms is overwhelming, in terms of both the amount of content produced every moment and the diversity of topics discussed. The real-time nature of the information produced by users has prompted researchers to analyse this content, in order to gain timely insight into the current state of affairs. Specifically, the microblogging service Twitter has been a recent focus of researchers to gather information on events occurring in real time. This article presents a survey of a wide variety of event detection methods applied to streaming Twitter data, classifying them according to shared common traits, and then discusses different aspects of the subtasks and challenges involved in event detection. We believe this survey will act as a guide and starting point for aspiring researchers to gain a structured view on state-of-the-art real-time event detection and spur further research in this direction.