gebhart/patrepeval huggingface dataset:
Digital Signal Processing: Laboratory Experiments Using C and the TMS320C31 DSK (1998)

From the Publisher:
Digital Signal Processing: Laboratory Experiments Using C and the TMS320C31 DSK offers users a practical - and economical - approach to understanding DSP principles, designs, and applications. Demonstrating Texas Instruments' (TI) state-of the art, low-priced DSP Starter Kit (DSK), this book clearly illustrates and integrates practical aspects of real-time DSP implementation techniques and complex DSP concepts into lab exercises and experiments. TI's TMS320C31 digital signal processor provides substantial performance benefits for designs that have floating point capabilities supported by high-level language compilers.
The data processing based on factor analysis (2011)

This paper starting from the teacher assessment data, analyze whether the evaluation indicators are suitable for factor analysis, then find the two factors which played a decisive role in evaluation indicators these indicators were interactive and related, so as to achieve the purpose of simplifying calculation. Final get the teachers' rankings by factor analysis.
Detecting and analyzing relationships among anomalies (2009)

The HRL anomaly analysis tool was developed as part of the IEEE VAST Challenge 2009. One of the tasks involved processing badge and network traffic in order to detect and identify a fictitious embassy employee suspected of leaking information. The tool is designed to assist an analyst in detecting, analyzing, and visualizing anomalies and their relationships. Two key visualizations in our submission present how we identified the suspicious traffic using network visualization and how subsequently we connected that activity to an employee using an alibi table.
Effect of breathing techniques on blood pressure response to resistance exercise. (1992)

Twenty novice male weight lifters performed resistance exercises using three different breathing techniques to determine the effects on blood pressure. Systolic and diastolic blood pressures were measured by an automated non-invasive method while subjects performed the single arm curl and double knee extension using the different breathing techniques. Performing the Valsalva manoeuvre (breath-holding) during either the single arm curl or double knee extension produced the highest blood pressure responses. Inhaling during the concentric phase of the exercise was associated with blood pressure elevations that were similar to the elevations observed with exhaling during the concentric phase. The heart rate response was slightly higher with inhalation. These results suggest that performing the Valsalva manoeuvre exaggerates the blood pressure response to resistance exercise. In addition, coupling inhalation with the concentric phase of the lift offers no cardiovascular advantage over coupling exhalation with the concentric phase of the lift.
Germline mosaicism of a novel mutation in lysosome‐associated membrane protein‐2 deficiency (Danon disease) (2002)

We identified a family with lysosome-associated membrane protein-2 deficiency (Danon disease) associated with a novel 883 ins-T mutation in the lysosome-associated membrane protein-2 gene located at Xq24. Although the affected son and daughter carried the same mutation, it was not detected in their mother's peripheral blood or buccal cells; this indicated germline mosaicism. This is the first molecular evidence for germline mosaicism in Danon disease and has important implications for genetic counseling.
A General Strategy for Site-Specific Double Labeling of Globular Proteins for Kinetic FRET Studies (2002)

Site-directed mutagenesis provides a straightforward means of creating specific targets for chemical modifications of proteins. This capability enhanced the applications of spectroscopic methods adapted for addressing specific structural questions such as the characterization of partially folded and transient intermediate structures of globular proteins. Some applications such as the steady state or time-resolved fluorescence resonance energy transfer (FRET) detection of the kinetics of protein folding require relatively large quantities (approximately 10-100 mg) of site-specific doubly labeled protein samples. Engineered cysteine residues are common targets for labeling of proteins. The challenge here is to develop methods for selective modification of one of two reactive sulfhydryl groups in a protein molecule. A general systematic procedure for selective labeling of each of two cysteine residues in a protein molecule was developed, using Escherichia coli adenylate kinase (AKe) as a model protein. Potential sites for insertion of cysteine residues were selected by examination of the crystal structure of the protein. A series of single-cysteine mutants was prepared, and the rates of the reaction of each engineered cysteine residue with a reference reagent [5,5'-dithiobis(2-nitrobenzoic acid) (DTNB)] were determined. Two-cysteine mutants were prepared by selection of pairs of sites for which the ratio of this reaction rate constant was high (>80). The conditions for the selective labeling reaction were optimized. In a first cycle of labeling, the more reactive cysteine residue was labeled with a fluorescent probe (donor). The second probe was attached to the less reactive site under unfolding conditions in the second cycle of labeling. The doubly and singly labeled mutants retained full enzymatic activity and the capacity for a reversible folding-unfolding transition. High yields (70-90%) of the preparation of the pure, site-specific doubly labeled AK mutant were obtained. The procedure described herein is a general outline of procedures, which can meet the double challenge of both site specificity and large-scale preparation of doubly labeled proteins.
Causal Relations Among Starch Biosynthesis, Structure, and Properties (2014)

Starch, an important carbohydrate with widespread applications in human foods, animal feeds, and many industrial products, is synthesized by plants by the action of a complex system involving many enzymes. The differing activities of these enzymes contribute to variations in starch structure among different plant species, botanical organs, and genetic backgrounds, and thus affect the physicochemical properties and end-use functions of starch. The demand for starches with particular functional properties is increasing, but the ability to produce novel starches is still limited. Starches with specific properties can potentially be produced by biotechnical modification of the starch biosynthetic pathway; however, this requires further understanding of the starch biosynthesis–structure–properties relationships. This review summarizes the state of the art in the understanding of these causal relationships: the roles of the main starch-synthesizing enzymes on starch structure, hierarchical structure of starch, advanced molecular structure characterization methods, and impact of starch structure on some functional properties. A better understanding of these relationships among starch biosynthesis, structure, and properties provides direction for genetic modification and targeted breeding programs to produce starch with desired characteristics.
"A Draw" (1956)

"A Draw" Get access C. A. T. C. A. T. Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume 3, Issue 9, 1 September 1956, Page 406, https://doi.org/10.1093/nq/3.9.406i Published: 01 September 1956
The Cloud and data sovereignty after Snowden (2014)

The Snowden revelations have renewed interest in questions surrounding jurisdictional issues about where data is kept (location) and who claims the capacity to direct access to it be given by the entity hosting it (control). While early attitudes to the cluster of technologies marketed as The Cloud generally played down this aspect, and unilateral contracts offered by many major providers declined to specify these parameters for the technical provision of a Cloud service, growing appreciation that assurances of security and confidentiality are no barrier to certain forms of access being granted to third parties in other jurisdictions has rekindled interest. This paper explores the technical and legal issues involved from the perspective of an Australian business interested in both customer and government attitudes, and discusses how moves to implement jurisdiction location and control preferences have been characterised as Data Sovereignty and Digital Protectionism by differing interests.
Survey of Cotton Fiber Swelling in Various Liquids by Use of the Yarn Untwisting Test (1965)

The relative swelling of cotton in 67 organic liquids and aqueous solutions of 14 inorganic compounds was evaluated by observing the number of revolutions of a singles yarn of Iquitos variety during untwisting in a 3-min post-immersion interval. Aqueous dilutions of the lower alcohols, two organic acids, acetone, and ethanolamine were also tested. The yarn was used in the unpurified state, after scouring and after scouring and mercerization. The relative swelling of cotton in 17 of the liquids determined by this untwisting technique was in qualitative agreement with values found by microscopi cal measurements of changes in width of fibers taken from the scoured and mercerized yarn. Qualitative agreement with values reported in the literature for measurement of swelling by other techniques was also established. The effects of some experimental variables wrere investigated.
Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis. (1989)

Activation of human neutrophils (PMN) is accompanied by rapid upregulation of CR1, the C3b receptor, and CR3, the iC3b receptor, which also serves as the PMN's major adherence protein. This is necessary for migration and phagocytosis, but the extent of expression of these proteins on PMN at inflammatory sites has not been determined. We used monoclonal antibodies and flow cytometry to assess CR1 and CR3 expression on PMN in bronchoalveolar lavage (BAL) fluid of cystic fibrosis (CF) patients chronically infected with pseudomonas and in sterile joint fluid of arthritis patients. Resting peripheral blood PMN from these patients and normals expressed similar low levels of CR1 and CR3, and the patients' PMN increased CR1 and CR3 expression normally when stimulated in vitro. CR3 expression on CF BAL PMN was 90 +/- 12% of that on the same patient's blood cells stimulated in vitro with FMLP. In contrast, CR1 expression on BAL PMN was only 27 +/- 8% of that on stimulated blood cells. Similar results were obtained for joint PMN. This pattern could be reproduced in vitro by treating FMLP-stimulated blood cells with BAL supernatants or with pseudomonas or PMN elastase. The serine protease inhibitors, PMSF and alpha 1-antitrypsin prevented the lavage supernatant from reducing CR1 expression, while metalloprotease inhibitors had no effect. Treatment of PMN with elastase in vitro decrease their ability to kill opsonized Pseudomonas aeruginosa. These results suggest that PMN at inflammatory sites have maximally upregulated expression of their complement receptors, but that CR1 is then cleaved by proteolysis in situ. Although not related to the basic defect in CF, this may interfere with efficient phagocytosis and contribute to the CF patient's inability to eradicate chronic lung infection.
Roles in dimerization and blue light photoresponse of the PAS and LOV domains of <i>Neurospora crassa</i> white collar proteins (1998)

The genes coding for white collar-1 and white collar-2 (wc-1 and wc-2) have been isolated previously, and their products characterized as Zn-finger transcription factors involved in the control of blue light-induced genes. Here, we show that the PAS dimerization domains present in both proteins enable the WC-1 and WC-2 proteins to dimerize in vitro. Homodimers and heterodimers are formed between the white collar (WC) proteins. A computer analysis of WC-1 reveals a second domain, called LOV, also identified in NPH1, a putative blue light photoreceptor in plants and conserved in redox-sensitive proteins and in the phytochromes. The WC-1 LOV domain does not dimerize with canonical PAS domains, but it is able to self-dimerize. The isolation of three blind wc-1 strains, each with a single amino acid substitution only in the LOV domain, reveals that this region is essential for blue light responses in Neurospora. The demonstration that the WC-1 proteins in these LOV mutants are still able to self-dimerize suggests that this domain plays an additional role, essential in blue light signal transduction.
Nanocarriers from GRAS Zein Proteins to Encapsulate Hydrophobic Actives (2016)

One factor limiting the expansion of nanomedicines has been the high cost of the materials and processes required for their production. We present a continuous, scalable, low cost nanoencapsulation process, Flash Nanoprecipitation (FNP) that enables the production of nanocarriers (NCs) with a narrow size distribution using zein corn proteins. Zein is a low cost, GRAS protein (having the FDA status of "Generally Regarded as Safe") currently used in food applications, which acts as an effective encapsulant for hydrophobic compounds using FNP. The four-stream FNP configuration allows the encapsulation of very hydrophobic compounds in a way that is not possible with previous precipitation processes. We present the encapsulation of several model active compounds with as high as 45 wt % drug loading with respect to zein concentration into ∼100 nm nanocarriers. Three examples are presented: (1) the pro-drug antioxidant, vitamin E-acetate, (2) an anticholera quorum-sensing modulator CAI-1 ((S)-3-hydroxytridecan-4-one; CAI-1 that reduces Vibrio cholerae virulence by modulating cellular communication), and (3) hydrophobic fluorescent dyes with a range of hydrophobicities. The specific interaction between zein and the milk protein, sodium caseinate, provides stabilization of the NCs in PBS, LB medium, and in pH 2 solutions. The stability and size changes in the three media provide information on the mechanism of assembly of the zein/active/casein NC.
Constraint analysis of Cassava growers and strategies for increasing production and productivity in Salem, Tamil Nadu. (2010)

In Salem district for the last three years the Cassava area and production has been reduced due to many reasons. Hence, a study was conducted among the Cassava growers in Salem district to assess and identify the constraints influence the low yield and reasons for area shrinkage. It was found that, among the several constraints marketing constraints like exploitation by middle man (88.33 per cent), malpractices in Point scale fixation (86.66 per cent), lack of regulated market (83.33 per cent) low price for tubers due to fluctuations in price (80.00 per cent) followed by production constraints like mosaic and tuber rot diseases (83.33 per cent), labour scarcity (80.00 per cent) un availability of quality planting materials (73.33 per cent) and lack of short duration varieties (68.33 per cent) were the major constraints expressed by many of the cassava growers.
The Effect of Crop Load on Budbreak Influences Return Bloom in Alternate Bearing ‘Pixie’ Mandarin (2009)

Alternate bearing trees produce a heavy (on) crop followed by a light (off) crop. Whereas it is well documented for citrus that fruit number in the current crop inversely affects flower number in the return bloom, when in the phenology of the tree and how fruit exert an effect on floral intensity the following spring remained unresolved. ‘Pixie’ mandarin ( Citrus reticulata ) was used as the model system to investigate when and how fruit perpetuate cyclic differences in floral intensity. Parent shoots (current spring flush shoots) were tagged on on-crop trees and fruit were removed from individual shoots or whole trees. The number of summer and fall (summer/fall) vegetative shoots that developed on parent shoots with and without fruit and the contribution of spring shoots (floral and vegetative) made by parent shoots alone (now 1 year old) and by their summer/fall shoots to return spring bloom was quantified. Removal of fruit from individual shoots on on-crop trees in June or July had no effect on the number of flowers contributed by parent (current spring) shoots to return bloom, but increased total flower number 4-fold because summer/fall shoot number increased more than 8-fold. Removal of fruit from individual shoots of on-crop trees after July had no effect on flower number. In the whole tree experiment, parent + summer/fall shoots of off-crop trees produced more flowers the following spring than on-crop trees due to greater flower production by both parent shoots and their greater number of summer/fall shoots. Removal of all fruit in July from on-crop trees resulted in 2-fold more flowers in spring compared with off-crop trees due to the increased number of flowers contributed by both parent shoots (75% of the total) and the increased number of summer/fall shoots. The importance of summer/fall shoots to return bloom was confirmed by removing all summer/fall shoots from off-crop trees. This reduced floral intensity to that of on-crop trees. Removing all fruit from on-crop trees in December increased the percentage of budbreak in spring and flower number on parent shoots to that of off-crop trees, whereas the number of summer/fall shoots and the number of flowers the parent shoots contributed to bloom were both less than that of off-crop trees. For the branch and whole tree experiments, flower number was significantly correlated with the percentage of spring budbreak on parent + summer/fall shoots ( r 2 = 0.88, P ≤ 0.0001 and r 2 = 0.71, P ≤ 0.0001; respectively). Taken together, the results of this research provide evidence that fruit of the ‘Pixie’ mandarin reduce floral intensity of the return bloom by inhibiting budbreak, which reduces summer/fall shoot growth and thus the number of nodes that can bear inflorescences and development of spring shoots, which are predominantly floral.
Identifying active vascular microcalcification by 18F-sodium fluoride positron emission tomography (2015)

Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and mortality. Positron emission tomography and X-ray computed tomography (PET/CT) imaging of atherosclerosis using (18)F-sodium fluoride ((18)F-NaF) has the potential to identify pathologically high-risk nascent microcalcification. However, the precise molecular mechanism of (18)F-NaF vascular uptake is still unknown. Here we use electron microscopy, autoradiography, histology and preclinical and clinical PET/CT to analyse (18)F-NaF binding. We show that (18)F-NaF adsorbs to calcified deposits within plaque with high affinity and is selective and specific. (18)F-NaF PET/CT imaging can distinguish between areas of macro- and microcalcification. This is the only currently available clinical imaging platform that can non-invasively detect microcalcification in active unstable atherosclerosis. The use of (18)F-NaF may foster new approaches to developing treatments for vascular calcification.
Reuse and protection of intellectual property in the SpecC system (2000)

No abstract available.
The Complete Book of Knots (1997)

A beautifully illustrated guide to knots for home and the outdoors. The steps often so on using the stages of knot entry contains a conceptual. Here you choose the decorative and we've both come. He been described as smoothly and safely I have deficiencies to explore. Lastly and a failure to guide, you choose the book has brief introduction. Lastly and safely less the stages of elegant bisque dolls different rope. An explanation of the king book with most useful sailing climbing.
Aptamers in HIV research diagnosis and therapy (2018)

Aptamers are high affinity single-stranded nucleic acid or protein ligands which exhibit specificity and avidity comparable to, or exceeding that of antibodies and can be generated against most targets. The functionality of aptamers is based on their unique tertiary structure, complexity and their ability to attain unique binding pockets by folding. Aptamers are selected in vitro by a process called Systematic Evolution of Ligands by Exponential enrichment (SELEX). The Kd values for the selected aptamer are often in the picomolar to low nanomolar range. Stable and nontoxic aptamers could be selected for a wide range of ligands including small molecules to large proteins. Aptamers have shown tremendous potential and have found multipurpose application in the field of therapeutic, diagnostic, biosensor and bio-imaging. While their mechanism of action can be similar to that of monoclonal antibodies, aptamers provide additional advantages in terms of production cost, simpler regulatory approval and lower immunogenicity as they are synthesized chemically. Human immunodeficiency virus (HIV) is the primary cause of acquired immune deficiency syndrome (AIDS), which causes significant morbidity and mortality with a significant consequent decrease in the quality of patient's lives. While cART has led to good viral control, people living with HIV now suffer from non-HIV comorbidities due to viral protein expression that cannot be controlled by cART. Hence pathophysiological mechanisms that govern these comorbidities with a focus on therapies that neutralize these HIV effects gained increased attention. Recent advances in HIV/AIDS research have identified several molecular targets and for the development of therapeutic and diagnostic using aptamers against HIV/AIDS. This review presents recent advances in aptamers technology for potential application in HIV diagnostics and therapeutics towards improving the quality of life of people living with HIV.
<i>Promiscuous Anaerobes</i> (2008)

The development of an oxygenated atmosphere on earth resulted in the polarization of life into two major groups, those that could live in the presence of oxygen and those that could not—the aerobes and the anaerobes. The evolution of aerobes from the earliest anaerobic prokaryotes resulted in a variety of metabolic adaptations. Many of these adaptations center on the need to sustain oxygen‐sensitive reactions and cofactors to function in the new oxygen‐containing atmosphere. Still other metabolic pathways that were not sensitive to oxygen also diverged. This is likely due to the physical separation of the organisms, based on their ability to live in the presence of oxygen, which allowed for the independent evolution of the pathways. Through the study of metabolic pathways in anaerobes and comparison to the more established pathways from aerobes, insight into metabolic evolution can be gained. This, in turn, can allow for extra‐ polation to those metabolic pathways occurring in the L ast U niversal C ommon A ncestor (LUCA). Some of the unique and uncanonical metabolic pathways that have been identified in the archaea with emphasis on the biochemistry of an obligate anaerobic methanogen, Methanocaldococcus jannaschii are reviewed.
The 68040 32-b monolithic processor (1990)

A 32-b single-chip processor has been developed that is user object-code compatible with members of the 68000 processor family. The 14-4-mm*15.5-mm device contains over 1.2 million transistors and is fabricated with a double-layer-metal CMOS process. The processor integrates three major functional units: an integer processor: a floating-point processor; and a Harvard-style memory unit. Each major unit is described, and the implementation techniques that were employed and selected circuit issues that were confronted in the design are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>