gebhart/patrepeval huggingface dataset:
Effect of defect clusters on carrier recombination in high-resistivity CdZnTe (2013)

Carrier recombination in high-resistivity CdZnTe is investigated using the non-contact Defect Specific Photoconductance (DSPC) method that allows for the separation of the photoconductance components associated with recombination at point defects and defect clusters. Unlike photoconductance component controlled by the recombination at point defects that decays exponentially upon cessation of illumination, the component associated with carrier recombination at defect clusters decays logarithmically with time. It is shown that this decay is associated with formation of a Schottky-type depletion space-charge region around the cluster. In high-resistivity CdZnTe the time constant of the logarithmic decay exceeds 1 ms. Reduction of the height of cluster potential barrier with increasing photo-excited excess carrier density increases carrier recombination through the cluster states and leads to its dominance over the recombination through the point defects. At higher carrier injection densities the contribution of the carrier recombination through the clusters exceeds 80% of the total recombination rate.
High-performance liquid affinity chromatography. (1983)

Developpement d'une methode qui combine les avantages de la chromatographie d'affinite et de la chromatographie en phase liquide de haute performance: specificite, rapidite et sensibilite
Monte-Carlo-based perturbation and beam quality correction factors for thimble ionization chambers in high-energy photon beams (2008)

This paper presents a detailed investigation into the calculation of perturbation and beam quality correction factors for ionization chambers in high-energy photon beams with the use of Monte Carlo simulations. For a model of the NE2571 Farmer-type chamber, all separate perturbation factors as found in the current dosimetry protocols were calculated in a fixed order and compared to the currently available data. Furthermore, the NE2571 Farmer-type and a model of the PTW31010 thimble chamber were used to calculate the beam quality correction factor kQ. The calculations of kQ showed good agreement with the published values in the current dosimetry protocols AAPM TG-51 and IAEA TRS-398 and a large set of published measurements. Still, some of the single calculated perturbation factors deviate from the commonly used ones; especially prepl deviates more than 0.5%. The influence of various sources of uncertainties in the simulations is investigated for the NE2571 model. The influence of constructive details of the chamber stem shows a negligible dependence on calculated values. A comparison between a full linear accelerator source and a simple collimated point source with linear accelerator photon spectra yields comparable results. As expected, the calculation of the overall beam quality correction factor is sensitive to the mean ionization energy of graphite used. The measurement setup (source-surface distance versus source-axis distance) had no influence on the calculated values.
Segmentation of 3D lidar data in non-flat urban environments using a local convexity criterion (2009)

Present object detection methods working on 3D range data are so far either optimized for unstructured offroad environments or flat urban environments. We present a fast algorithm able to deal with tremendous amounts of 3D lidar measurements. It uses a graph-based approach to segment ground and objects from 3D lidar scans using a novel unified, generic criterion based on local convexity measures. Experiments show good results in urban environments including smoothly bended road surfaces.
Effect of exogenous melatonin on vascular reactivity and nitric oxide in postmenopausal women: role of hormone replacement therapy (2001)

The circulatory response to melatonin is conserved in postmenopausal women with but not without hormone replacement therapy. Maintenance of the cardiovascular response to melatonin, may be implicated in the reduced cardiovascular risk of postmenopausal women with hormone replacement therapy.
An Aspect of the Role of the Clock in a GPS Receiver (1984)

Analytic solutions for the least squares covariance and for steady state optimal estimate covariance have been derived. These solutions define and succinctly describe the relationship between clock performance, satellite geometry and system accuracy. It is seen that the clock attenuates the “bad geometry” effect associated with one-way ranging. The steady state solutions obtained depend on certain specializations of the system dynamics and on limit cases where the clock is either much better than or much worse than the position dead-reckoner.
Electronic and transport properties of Li-doped NiO epitaxial thin films (2018)

NiO is a p-type wide bandgap semiconductor of use in various electronic devices ranging from solar cells to transparent transistors. This work reports the controlling of conductivity and increase of work functions by Li doping.
Fabrication and Characterization of Multilayer Capacitors Buried in a Low Temperature Co‐Fired Ceramic Substrate (1997)

Multilayer ceramic capacitors designed to be embedded in a low temperature co‐fired ceramic substrate have been successfully fabricated. Low and high value capacitors were respectively embedded in the low K multilayer substrate and high K dielectric layer. The buried capacitor has a capacitance density range (1 kHz) from about 220 pF/cm 2 to 30 nF/cm 2 . The design took material compatibility and shrinkage characteristics specifically into account. The effects of heating rate and peak temperature holding time on the densification of the laminate were studied. The scanning electron micrograph revealed no evident cracking in the fired components. The electrical properties of the buried capacitors such as dissipation factor, insulation resistance and breakdown voltage were studied and found to be good for device application. The temperature dependence of the dissipation factor and coefficient of capacitance for the buried capacitor was also studied.
Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature. (1989)

The thermolabile large T antigen, encoded by the simian virus 40 early-region mutant tsA58, was used to establish clonal cell lines derived from rat embryo fibroblasts. These cell lines grew continuously at the permissive temperature but upon shift-up to the nonpermissive temperature showed rapidly arrested growth. The growth arrest occurred in either the G1 or G2 phase of the cell cycle. After growth arrest, the cells remained metabolically active as assayed by general protein synthesis and the ability to exclude trypan blue. The inability of these cell lines to divide at the nonpermissive temperature was not readily complemented by the exogenous introduction of other nuclear oncogenes. This finding suggests that either these genes establish cells via different pathways or that immortalization by one oncogene results in a finely balanced cellular state which cannot be adequately complemented by another establishment gene.
Parallelization, performance analysis, and algorithm consideration of Hough transform on chip multiprocessors (2008)

This paper presents a parallelization framework for emerging applications on the future chip multiprocessors (CMPs). With the continuing prevalence of CMP and the number of on-die cores increasing steadily for the foreseeable future, one key issue in harnessing the computation power of such a CMP is how to effectively manage and execute many threads at the same time. Hence, we study a parallelization framework, which includes (1) coarse-grain and fine-grain multi-threading, (2) performance analysis, and (3) algorithms changes. In particular, this paper shows how the Hough Transform can be parallelized, as an example. Starting with a sports soccer analysis workload that heavily uses Hough Transform to detect lines in sports soccer field, we extract the coarse-grain data-level parallelism and examine its scaling performance on an 8-core symmetric multiprocessor machine. After realizing the parallel performance limiting factors, we target to exploit the fine-grain data-level parallelism and evaluate its speedup on the 8-core machine and a simulated 64-core CMP. Due to parallel overhead and demanding memory requirements, this fine-grain parallelization doesn't contribute significant performance improvement. After that, we propose a new Hough Transform, and parallelize it in a fine-grain way. Experimental data shows that the new Hough Transform exposes a significant amount of concurrency and pretty good data locality. On the simulated 64-core CMP, we achieve parallel scaling of 61.7x, enabling real-time Hough Transform.
Hypoxia regulates PGE<sub>2</sub> release and EP1 receptor expression in osteoblastic cells (2007)

Changes in regional O(2) tension that occur during fracture and skeletal unloading may stimulate local bone cell activity and ultimately regulate bone maintenance and repair. The mechanisms by which bone cells sense and respond to changes in O(2) tension are unclear. In this study we investigated the effects of low O(2) on activation of the hypoxia response element (HRE), prostaglandin E(2) (PGE(2)) production, PGE(2) receptor (EP) expression and proliferation in MC3T3-E1 osteoblastic cells. Cells were cultured for up to 72 h in 2% O(2) (considered hypoxic), 5% O(2) (in the range of normal O(2) tension in vivo) or 21% O(2) (commonly used for cell culture). Cells cultured in 2% O(2) showed activation of the HRE, increased PGE(2) release, increased EP1 expression, and reduced cell proliferation compared to cells grown at 21% O(2). Similarly, cells cultured in 5% O(2) showed increased expression of EP1 and a trend toward a decrease in proliferation, but no activation of the HRE or increase in PGE(2) levels. Expression of EP2, EP3 and EP4 were not affected by O(2) tension. The differences in EP receptor profile observed in cells grown at 5% compared to 21% O(2) suggest that bone cell phenotype may be altered under routine cell culture conditions. Furthermore, our data suggest that hypoxia-dependent PGE(2) production and EP1 expression in bone cells may play a role in bone remodeling and repair in regions of compromised or damaged bone, where O(2) tension is low.
Tachykinin‐like Peptides and Their Receptors: A Review (1999)

Tachykinin-like peptides have been identified in many vertebrate and invertebrate species. On the basis of the data reviewed in this paper, these peptides can be classified into two distinct subfamilies, which are recognized by their respective sequence characteristics. All known vertebrate tachykinins and a few invertebrate ones share a common C-terminal sequence motif, -FXGLMa. The insect tachykinins, which have a common -GFX1GX2Ra C-terminus, display about 30% of sequence homology with the first group. Tachykinins are multifunctional brain/gut peptides. In mammals and insects, various isoforms play an important neuromodulatory role in the central nervous system. They are involved in the processing of sensory information and in the control of motor activities. In addition, members of both subfamilies elicit stimulatory responses on a variety of visceral muscles. The receptors for mammalian and insect tachykinins show a high degree of sequence conservation and their functional characteristics are very similar. In both mammals and insects, angiotensin-converting enzyme (ACE) plays a prominent role in tachykinin peptide metabolism.
Identification of genes important for growth of asymptomatic bacteriuria Escherichia coli in urine (2012)

Escherichia coli is the most important etiological agent of urinary tract infections (UTIs). Unlike uropathogenic E. coli, which causes symptomatic infections, asymptomatic bacteriuria (ABU) E. coli strains typically lack essential virulence factors and colonize the bladder in the absence of symptoms. While ABU E. coli can persist in the bladder for long periods of time, little is known about the genetic determinants required for its growth and fitness in urine. To identify such genes, we have employed a transposon mutagenesis approach using the prototypic ABU E. coli strain 83972 and the clinical ABU E. coli strain VR89. Six genes involved in the biosynthesis of various amino acids and nucleobases were identified (carB, argE, argC, purA, metE, and ilvC), and site-specific mutants were subsequently constructed in E. coli 83972 and E. coli VR89 for each of these genes. In all cases, these mutants exhibited reduced growth rates and final cell densities in human urine. The growth defects could be complemented in trans as well as by supplementation with the appropriate amino acid or nucleobase. When assessed in vivo in a mouse model, E. coli 83972carAB and 83972argC showed a significantly reduced competitive advantage in the bladder and/or kidney during coinoculation experiments with the parent strain, whereas 83972metE and 83972ilvC did not. Taken together, our data have identified several biosynthesis pathways as new important fitness factors associated with the growth of ABU E. coli in human urine.
The role of disordered protein regions in the assembly of decapping complexes and RNP granules (2013)

The removal of the 5' cap structure by the decapping enzyme DCP2 inhibits translation and generally commits the mRNA to irreversible 5'-to-3' exonucleolytic degradation by XRN1. DCP2 catalytic activity is stimulated by DCP1, and these proteins form the conserved core of the decapping complex. Additional decapping factors orchestrate the recruitment and activity of this complex in vivo. These factors include enhancer of decapping 3 (EDC3), EDC4, like Sm14A (LSm14A), Pat, the LSm1-7 complex, and the RNA helicase DDX6. Decapping factors are often modular and feature folded domains flanked or connected by low-complexity disordered regions. Recent studies have made important advances in understanding how these disordered regions contribute to the assembly of decapping complexes and promote phase transitions that drive RNP granule formation. These studies have also revealed that the decapping network is governed by interactions mediated by short linear motifs (SLiMs) in these disordered regions. Consequently, the network has rapidly evolved, and although decapping factors are conserved, individual interactions between orthologs have been rewired during evolution. The plasticity of the network facilitates the acquisition of additional subunits or domains in pre-existing subunits, enhances opportunities for regulating mRNA degradation, and eventually leads to the emergence of novel functions.
Divorce Under the Indiana Law, for Abandonment, Cruelty or Failure to Provide (1927)

No divorce can be granted unless some statute empowers the court to grant it for causes specified in the statute.This is elementary, and obtains in every state.'If some statute does not declare a divorce can be granted for a particular fault or delinquency, none can be granted.Unchastity is one of these instances in this state. 2Divorce cannot be granted merely because both of the parties desire one. 3 Thus where the defendant filed a cross-complaint praying that he be granted a divorce, the court said: "Nor does it matter that both have prayed a divorce.Their concurrent wish or even consent will not justify a divorce." 4 Nor can a divorce be granted to both the plaintiff and to the defendant on his cross bill.5In every divorce case the state is a third party. 6This is true when an appeal is taken. 7 And the court in a way represents the state, especially when there is no defense and the defendant does not appear.In that capacity the court may examine the plaintiff, and should ascertain if he is a fit person to receive a divorce, and if he has committed any marital offense; and if he has, refuse the divorce.
The effect of background color on asymmetries in color search (2004)

Many previous studies have shown that background color affects the discriminability and appearance of color stimuli. However, research on visual search has not typically considered the role that the background may play. Rosenholtz (2001a) has suggested that color search asymmetries result from the relationship between the stimuli and the background. Here we test the hypothesis that background color should have an effect on asymmetries in visual search based on color, using searches for color stimuli on different colored backgrounds. Observers searched for a single known target stimulus among homogeneous distractor stimuli. The target stimulus differed from the distractors only in chromaticity, but targets and distractors both differed from the backgrounds in luminance so that they were easily visible regardless of chromaticity. Target/distractor pairs differed primarily in saturation (Experiments 1, 2, & 3) or in hue (Experiment 4). Each member of each pair of colors served as target and distractor color on both achromatic and red backgrounds. When the stimuli were presented on an achromatic background, response times were shorter when the more saturated member of each pair of colors served as the target color. When the same stimuli were presented on a red background, the asymmetry was either reversed or abolished. When target and distractors differed in hue, there was little asymmetry on the achromatic background but a sizable asymmetry for some color pairs on the red background. On both backgrounds, the magnitude of the asymmetry varied with the difference between the stimulus colors and the background color. Results confirm that asymmetries in color search are dependent on the relationship between the stimulus colors and the background color. Two candidate models are suggested that show promise in predicting these experimental results: Rosenholtz' saliency model (1999, 2001a) and a modification to signal detection theory models in which the observation noise is proportional to the difference between target/distractor color and background color.
Dynamic Uncertain Causality Graph Applied to Dynamic Fault Diagnoses and Predictions With Negative Feedbacks (2015)

Intelligent systems are desired in dynamic fault diagnoses for large and complex systems such as nuclear power plants. Dynamic uncertain causality graph (DUCG) is such a system presented previously. This paper extends the DUCG methodology to deal with negative feedbacks, which is one of the most difficult problems in fault diagnosis, and predicts the fault development online. Two methods are presented. One does not involve causality propagation across time slices. Another involves causality propagation through time slices. A nuclear power plant simulator located at Tsinghua University is used to test the DUCG methodology. A typical experiment involving negative feedback is given, which jointly applies the methods separately presented in different papers, such as how to deal with dynamic fault diagnosis and directed cyclic graphs (DCGs), and the methods presented in this paper. Results show that DUCG is powerful in knowledge representation, diagnosing possible faults, and predicting developments of faults. It also demonstrates that DUCG is robust, which means that the DUCG inference does not rely much on the accuracy of probability parameters. The logics of diagnoses and predictions are graphically displayed, so that users know not only inference results, but also why they are correct.
Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas. (1994)

The gene for the hereditary disorder neurofibromatosis type 2 (NF2), which predisposes for benign CNS tumors such as vestibular schwannomas and meningiomas, has been assigned to chromosome 22 and recently has been isolated. Mutations in the NF2 gene were found in both sporadic meningiomas and vestibular schwannomas. However, so far only 6 of the 16 exons of the gene have been analyzed. In order to extend the analysis of an involvement of the NF2 gene in the sporadic counterparts of these NF2-related tumors, we have used reverse transcriptase-PCR amplification followed by SSCP and DNA sequence analysis to screen for mutations in the coding region of the NF2 gene. Analysis of the NF2 gene transcript in 53 unrelated patients with meningiomas and vestibular schwannomas revealed mutations in 32% of the sporadic meningiomas (n = 44), in 50% of the sporadic vestibular schwannomas (n = 4), in 100% of the tumors found in NF2 patients (n = 2), and in one of three tumors from multiple-meningioma patients. Of the 18 tumors in which a mutation in the NF2 gene transcript was observed and the copy number of chromosome 22 could be established, 14 also showed loss of (parts of) chromosome 22. This suggests that in sporadic meningiomas and NF2-associated tumors the NF2 gene functions as a recessive tumor-suppressor gene. The mutations detected resulted mostly in frameshifts, predicting truncations starting within the N-terminal half of the putative protein.
Transit time heterogeneity in canine small intestine: significance for oxygen transport. (1997)

We previously found that local O2 extraction efficacy in isolated pump-perfused intestine was enhanced when systemic reflex vasoconstriction was stimulated by hypovolemia (Samsel, R.W., and P.T. Schumacker. 1994. J. Appl. Physiol. 77: 2291-2298). The microvascular mechanism underlying this beneficial effect could involve a redistribution of flow between mucosa and serosa, or an adjustment in the heterogeneity of perfusion within those regions. We measured regional blood flows and distributions of flow and capillary erythrocyte transit times in two segments of small intestine in anesthetized dogs (n = 10). Each vascularly isolated segment of intestine was pump-perfused under high flow (O2 supply-independent VO2) and low flow (O2 supply-dependent) conditions. During the first gut segment, the animal was kept normovolemic using i.v. fluids to minimize reflex vasoconstriction. During the second, the animal was hemorrhaged to augment vasoconstriction (n = 7), or kept normovolemic to control for the effects of time (n = 3). Blood flow distributions were measured using 15 microm radiolabeled microspheres. Tissue blood volume was measured using 99mTc-labeled red blood cells. Capillary volume was determined as the product of tissue blood volume and the histologically derived fraction of vascular volume in the capillaries. Transit times were calculated as the ratio of capillary volume to flow. Each gut segment was fixed and sectioned into 350 approximately 100 mg tissue pieces for analysis. Data revealed significant spatial heterogeneity of blood flow and capillary transit times in both mucosa and muscularis, with relative dispersions (SD/Mean) ranging from 23 to 97%. Hypovolemia caused an increase in flow heterogeneity in muscularis at both high and low flow states, and in mucosa under high flow conditions. However, hypovolemia also elicited changes in capillary volume, such that transit time heterogeneity remained unchanged. Augmentation of vasoconstrictor tone caused a redistribution of flow toward mucosa (P < 0.003) under high and low flow conditions. This redistribution correlated with the improvements in O2 extraction ratio (P = 0.022). Thus, the improvement in gut O2 extraction efficacy seen with increased vasoconstriction may be explained mostly by an intramural redistribution of flow between mucosa and muscularis. Capillary transit time heterogeneity remained unchanged, suggesting that this variable is tightly regulated.