gebhart/patrepeval huggingface dataset:
Optimal Task Partitioning Model in Distributed Heterogeneous Parallel Computing Environment (2012)

Parallel computing systems compose task partitioning strategies in a true multiprocessing manner. Such systems share the algorithm and processing unit as computing resources which leads to highly inter process communications capabilities. We focus on real-time and non preemptive systems. A large variety of experiments have been conducted on the proposed algorithm. Goal of computation model is to provide a realistic representation of the costs of programming.
RAC-Filters with Position Weighted Metallic Strip Arrays (1982)

Reflective array compressors with metal gratings are attractive devices because they can be fabricated in a single layer photolithographic process. However, known weighting techniques for'achieving the desired time response suffer either fran sensitivity to fabrication tolerances or fran complex reflection behaviour. We use a new amplitude weighting scheme whereby only the positions of metallic strips in the array are shifted. These shifts are caused by an additional phase modulation of the desired waveform with an oscillating function whereby the number of oscillations exceeds the time-bandwidth product. The envelope of the oscillating function depends on the required weighting. This weighting technique is free of additional secondary effects, insensitive to technological linewidth-deviations and accurate to calculate and to design. Fabricated matched filter sets with a time-bandwidth product of 12 and nonlinear frequency modulation (FM) attain -41 dB sidelobes in the compressed pulse.
A randomized, dose–response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer (2012)

Pain response was seen in up to 71% of the patients with a dose response observed 2 weeks after administration. The highly tolerable side-effect profile of radium-223 previously reported was confirmed.
Molecular basis of hypoxanthine-guanine phosphoribosyltransferase deficiency in ten subjects determined by direct sequencing of amplified transcripts. (1989)

Hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency is an inborn error of purine metabolism. Mutant HPRT gene sequences from patients deficient in enzyme activity have previously been characterized by cDNA cloning or amino acid sequencing techniques. The presence of HPRT-specific mRNA in nearly all deficient subjects, as well as the small size of the HPRT mRNA (1,400 bp), make the polymerase chain reaction (PCR) an alternative for the identification of mutations at this locus. In this report we use the PCR to identify previously undetermined mutations in HPRT mRNA from B lymphoblasts derived from 10 deficient individuals. Six of these variants contain single point mutations, three contain deletions, and one contains a single nucleotide insertion. Several of these mutations map near previously identified HPRT variants, and are located in evolutionarily conserved regions of the molecule.
Virtual private networks-new strategies for secure enterprise networking (2002)

Many corporations are reluctant to do business over the public telecommunications infrastructures. When they deal with outside service providers they worry about service quality, network performance, and data security. Fortunately, new IP-routed virtual private networks (VPNs) allow businesses to preserve control of their data traffic, even when routed across public networks. VPNs extend the corporate computer network out to distant offices, home workers, salespeople, and business partners. But, rather than using expensive dedicated leased lines, VPNs use the worldwide IP network services, including the Internet and service provider IP backbones. Rather than dialing in at long distance rates, remote users can make a local Internet call. Network managers can cost-efficiently increase the span of the corporate network.
1-mW CW-RT monolithic VCSEL at 1.55 μm (1999)

We demonstrate the first result of a high-power (1 mW) continuous-wave room-temperature vertical-cavity surface-emitting laser emitting at 1.55 μm using a single InP substrate. The whole structure was grown monolithically using gas source molecular beam epitaxy and incorporates two original approaches. The first originality consists in the growth of a metamorphic GaAs-AlAs Bragg mirror directly on an InP-based cavity. The second novel idea is to use a tunnel junction for current injection. Moreover by using these two approaches the processing is very simple and, therefore, fulfills the goal for low-cost laser production in access and interconnections applications.
Partial-Birth Abortion, Congress, and the Constitution (1998)

The political debate over abortion during the past 25 years has shifted among various dichotomous views of the world: life versus choice, fetus versus woman, fetus versus baby, constitutional right versus states' rights, government versus physician, physician and patient versus state legislature. Hundreds of statutes and almost two dozen Supreme Court decisions on abortion later, the core aspects of Roe v. Wade, 1 the most controversial health-related decision by the Court ever, remain substantially the same as they were in 1973. Attempts to overturn Roe in both the courtroom and the legislature have failed. Pregnant women still have a constitutional right . . .
Brain morphometry volume in autistic spectrum disorder: a magnetic resonance imaging study of adults (2008)

Within ASD adults, the bulk volume of cerebellum is reduced irrespective of diagnostic subcategory. Also the significant increase in peripheral CSF may reflect differences in cortical maturation and/or ageing.
Development and Application of a Polymerase Chain Reaction Assay for Mycoplasma synoviae (1993)

Mycoplasma synoviae (MS) species-specific primers selected from the 16S rRNA sequence were evaluated by polymerase chain reaction (PCR). The MS primers were MS-1 (5'-GAAGCAAAATAGTGATATCA-3') and MS-2 (5'-GTCGTCTCCGAAGTTAACAA-3'). Analysis of cultures of avian mycoplasmas using the MS PCR indicated 100% specificity and sensitivity: 55 individual isolates of MS tested PCR-positive, and 44 isolates of eight other species of avian mycoplasmas tested PCR-negative. The MS PCR will detect 100 colony-forming units of MS. Analysis of 122 flock data sets indicated a sensitivity for the MS PCR test of 82% and a specificity of 100% as determined by comparison with culture, serology (serum plate test, hemagglutination-inhibition, enzyme-linked immunosorbent assay), epizootiology, and history.
Story of Development of High-Pressure Processed Foods, Part 2-A method of producing rapidly cookable processed unpolished rice. (1997)

Whole-rice foods are well known to be beneficial for health. This is a story the development of our processed unpolished rice with excellent cookability, openly disclosing our failures in the course of these development. Our experience will hopefully be useful for any kind of rice research in the future.
Changes in critical care beds and occupancy in the United States 1985–2000: Differences attributable to hospital size (2006)

Across hospitals of all sizes, CCM bed numbers are increasing, whereas non-CCM bed numbers are decreasing. Although the CCM bed capacity is increasing at a greater percentage rate in smaller hospitals, the assignment of hospital beds to CCM remains higher in the larger hospitals. In addition, CCM bed occupancy is greater in larger institutions. These findings may help guide the future development of hospital size-based CCM benchmarking standards and guidelines.
A reservation-based multicasting protocol for WDM local lightwave networks (2002)

A wavelength-division multiplexing (WDM) based multicasting protocol for a single-hop broadcast-and-select local lightwave network is proposed. The approach employs a control-channel-based media-access protocol that schedules multicast packets while incorporating arbitrary transceiver tuning times and propagation delays. An arbitrary number of data channels (W) supply communication bandwidth to N nodes, where N/spl ges/W. An additional control channel is used for synchronization and scheduling. Each node is equipped with one fixed transmitter and one fixed receiver on the control channel, as well as one tunable (wavelength-agile) transmitter and one or more tunable receivers for data channel access. Results suggest the WDM single-hop multicasting experiences very good performance when multicast size is either small or very large, or when nodes are equipped with multiple receivers.
Synchronous motor adjustable frequency drive systems for large mechanical draft fans (1980)

The development of the modern full hollow airfoil-bladed centrifugal fan described has made it possible to achieve mechanical efficiencies well above 90 percent. The efficiency, however, suffers greatly if it is necessary to reduce flow in the conventional way by the adjustment of either the inlet dampers or the inlet vanes, whichever is provided, while maintaining constant fan speed.
Enhancement of Efficiency and Lifetime of Blue Organic Light-Emitting Diodes Using Two Dopants in Single Emitting Layer (2012)

We have demonstrated efficient blue organic light-emitting diode with the structure of indium tin oxide/4,4′,4″- tris ( N -(2-naphthyl)- N -phenyl-amino)triphenylamine/1,4- bis [ N -(1-naphthyl)- N ′-phenylamino]-4,4′-diamine/9,10- di (2-naphthyl)anthracene (ADN): 1-4- di -[4-( N,N-di -phenyl)amino]styryl-benzene (DSA-ph) 3 wt%/ tris -(8-hydroxyquinoline)aluminum/LiF/Al. Improved efficiencies and longer operational lifetime were obtained by codoping a styrylamine-based dopant BD-3 (0.1 wt%) into the emitting layer of ADN doped with DSA-ph compared to the case of non-codoping. This was due to the improved charge balance and expansion of exciton recombination zone. The better charge balance was obtained by reducing the electron mobility of ADN which was higher than the hole mobility in the case of non-codoping.
Bcl-2 Overexpression in the HaCaT Cell Line is Associated With A Different Membrane Fatty Acid Composition and Sensitivity to Oxidative Stress (1998)

Different mechanisms have been proposed for the activity of the Bcl-2 proto-oncogene product. A bona fide antioxidant activity and a pro-oxidant setting up of the cell have been suggested using different experimental models, yet many uncertainties exist about the biochemical mechanism of Bcl-2 action. In the present paper, we report the characterization of the cellular response to mild oxidative stress of a cultured cell line of immortalized keratinocytes (HaCaT), overexpressing the Bcl-2 oncogene product. A sublethal oxidative stress was induced by 1 h treatment with 200 μM tert-butyl-hydroperoxide (t-BOOH). Following peroxide treatment, the formation of reactive oxygen species was lower in Bcl-2 expressing cells, suggesting a better capacity to counter oxidative stress. Total Superoxide Dismutase activity was induced by oxidative t-BOOH treatment in bcl-2 transfected cells, which also accumulated less damage to membrane lipids and proteins, as assessed by TBA-RS and carbonyl formation respectively. On the other hand, the formation of 4-hydroxy-nonenal, a more specific marker of peroxidative damage to polyunsaturated fatty acids, was higher in bcl-2 transfected cells than in control cells. Bcl-2 over-expression was also associated with significant changes in the fatty acid composition of cell membranes. Transfected cells presented a higher proportion of mono-unsaturated fatty acids and ω6 poly unsaturated fatty acids and a lower proportion of penta-enoic PUFA, thus resulting in a higher unsaturation index with respect to control cells. Changes in Protein kinase C activity were also associated to bcl-2 expression, possibly resulting from the differences in membrane fatty acid composition. These data may be an important background for the understanding of Bcl-2 involvement in the control of apoptotic response as well as in the induction of antioxidant cell defenses against oxidative stress.
Metallothionein synthesis and degradation: relationship to cadmium metabolism. (1979)

Metallothionein is an integral component of the mechanism that regulates the metabolism of cadmium and zinc. The synthesis of this protein can be "induced" by oral or parenteral administration of either metal. The metallothionein mRNA content of liver polysomes is increased shortly after an influx of small amounts of either metal into hepatocytes. After sufficient amounts of this poly (A+) RNA have been synthesized, there is a concomitant increase in metallothionein biosynthesis and metal binding. Unlike synthesis, the degradation of metallothionein is markedly influenced by the species of metal bound. By using in vivo and in vitro techniques, it has been possible to demonstrate that resistance of metallothionein to degradation follows the order: thionein less than zinc metallothionein less than cadmium metallothionein. Moreover, while the polypeptide chains of cadmium metallothionein are degraded, it appears that liberated cadmium ions are quickly incorporated into nascent chains of thionein. The latter explains why the cadmium content of liver and kidney increases with age and environmental exposure. Since both zinc and cadmium bind to metallothionein, it appears that the binding sites provided by this inducible species provide a locus for interaction between zinc, a nutrient, and cadmium, an environmental contaminant.
Stresses in horizontal storage vessels - a comparison of theory and experiments (1982)

This paper presents the salient features of the experimental work carried out on a series of horizontal storage vessels. These include a 3.66 m diameter gas receiver and two smaller vessels each of 0.91 m diameter. The saddles used to support the vessels represent the two extremes of saddle design where the cantilever section is either of ‘flexible’ or ‘rigid’ construction and in both cases welded to the vessels. All the vessels were extensively strain gauged in the region of the saddle supports and at the centre of the vessel. Hydraulic, pressure surcharge and pneumatic tests were carried out on the vessels. Typical experimental results have been compared with the theoretical analysis described in (1) † . It is found that a satisfactory measure of agreement is obtained for both the flexible and more rigid results for the water fill tests, but that the pressure results are sensitive to vessel imperfection which are not considered in the theoretical analysis (1).
Multibit Sigma - Delta A/D converter incorporating a novel class of dynamic element matching techniques (1992)

A dynamic element matching technique is applied to multibit sigma-delta modulators. The approach translates the harmonic distortion components of a nonideal digital-to-analog converter (DAC) in the feedback loop of a sigma-delta modulator to high-frequency components, which can then be filtered out by the decimation filter. Computer simulations have confirmed that with this approach a third-order sigma-delta modulator employing a 3-bit forward ADC, a 3-bit feedback DAC with a random mismatch of 0.1% can achieve a 104-dB (17+bit) dynamic range and a harmonic distortion below 100 dB, with an oversampling ratio of 64. The technique does not generate any tone in the passband.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Deterministic Delivery of a Single Atom (2001)

We report the realization of a deterministic source of single atoms. A standing-wave dipole trap is loaded with one or any desired number of cold cesium atoms from a magneto-optical trap. By controlling the motion of the standing wave, we adiabatically transport the atom with submicrometer precision over macroscopic distances on the order of a centimeter. The displaced atom is observed directly in the dipole trap by fluorescence detection. The trapping field can also be accelerated to eject a single atom into free flight with well-defined velocities.
Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake (2015)

The basic DNA recognition region of the GCN4 protein comprising 23 amino acids has been modified to contain two optimally positioned cysteines which have been linked and stapled using cross-linkers of suitable lengths. This results in stapled peptides with a stabilized α-helical conformation which allows for DNA binding and concurrent enhancement of cellular uptake.
Interpol (2013)

Abstract With its 190 member nations, Interpol is the world's largest international police organization. Its primary objective is to reduce criminal activity across the world by facilitating the cross‐border exchange of police information and promoting cooperation among law enforcement authorities in its member nations. One of Interpol's most important functions is to assist its members through the issuance of notices that facilitate the sharing of crime‐related information among countries and are the main instruments of international police cooperation. These notices are discussed in this entry, as are the databases provided by Interpol to law enforcement authorities in its member countries who are connected through a secure communications system giving them real‐time access to current global crime data.
Modified Repeated Median Filters (2004)

We discuss moving window techniques for fast extraction of a signal comprising monotonic trends and abrupt shifts from a noisy time series with irrelevant spikes. Running medians remove spikes and preserve shifts, but they deteriorate in trend periods. Modified trimmed mean filters use a robust scale estimate such as the median absolute deviation about the median (MAD) to select an adaptive amount of trimming. Application of robust regression, particularly of the repeated median, has been suggested for improving upon the median in trend periods. We combine these ideas and construct modified filters based on the repeated median offering better shift preservation. All these filters are compared w.r.t. fundamental analytical properties and in basic data situations. An algorithm for the update of the MAD running in time O(log n) for window width n is presented as well.
Colocation of Genes Encoding a tRNA-mRNA Hybrid and a Putative Signaling Peptide on Complementary Strands in the Genome of the Hyperthermophilic Bacterium<i>Thermotoga maritima</i> (2006)

In the genome of the hyperthermophilic bacterium Thermotoga maritima, TM0504 encodes a putative signaling peptide implicated in population density-dependent exopolysaccharide formation. Although not noted in the original genome annotation, TM0504 was found to colocate, on the opposite strand, with the gene encoding ssrA, a hybrid of tRNA and mRNA (tmRNA), which is involved in a trans-translation process related to ribosome rescue and is ubiquitous in bacteria. Specific DNA probes were designed and used in real-time PCR assays to follow the separate transcriptional responses of the colocated open reading frames (ORFs) during transition from exponential to stationary phase, chloramphenicol challenge, and syntrophic coculture with Methanococcus jannaschii. TM0504 transcription did not vary under normal growth conditions. Transcription of the tmRNA gene, however, was significantly up-regulated during chloramphenicol challenge and in T. maritima bound in exopolysaccharide aggregates during methanogenic coculture. The significance of the colocation of ORFs encoding a putative signaling peptide and tmRNA in T. maritima is intriguing, since this overlapping arrangement (tmRNA associated with putative small ORFs) was found to be conserved in at least 181 bacterial genomes sequenced to date. Whether peptides related to TM0504 in other bacteria play a role in quorum sensing is not yet known, but their ubiquitous colocalization with respect to tmRNA merits further examination.
Influence of the involuntary underetching on the mechanical properties of tunable Fabry-Perot filters for optical communications (2001)

We present in this paper the mechanical analysis of tunable InP-based Fabry-Perot filters. These filters are composed by a top and a bottom InP/air Bragg mirrors with a central air microcavity. The tunability is achieved by changing electrostatically the cavity thickness. We have developed a theoretical model using finite elements analysis (FEA) calculation method, which permits to evaluate the mechanical deformation of the central cavity. This model considers the electrostatic force between the two freestanding layers delimiting the central cavity. Using this model, we have analyzed the tuning performance of two kinds of device: a bridge structure and a square membrane. We have evaluated the influence on the mechanical performances of the involuntary underetching of the clamped ends at the freestanding layers extremities. The theoretical results have been compared to experimental ones obtained by optical reflectivity measurements.
Membrane Structural Biology (2008)

Membrane Structural Biology brings together a physicochemical analysis of the membrane with the latest structural biology on membrane lipids and proteins to offer an exciting portrayal of biomembranes. Written with remarkable clarity, this text appears at a time when membranes have moved back into the scientific spotlight and will provide a unique foundation for advanced students and working scientists. The structure, function, and biogenesis of membrane lipids and proteins are examined, bioinformatics and computational approaches to membrane components are introduced, and the high-resolution structures that are giving new insights into the vital roles membranes play are discussed. The many correlations between membrane research and human health are discussed and key themes for future work in this area are identified. Membrane structural biology is poised to answer many basic and applied questions and this cutting-edge text will provide a solid grounding for all those working in this field.
PLL propagation delay-time influence on linewidth requirements of optical PSK homodyne detection (1991)

Phase-locked loop (PLL) propagation delay-time influence on optical homodyne detection was investigated both theoretically and experimentally. Applying the Pade approximation, which is often used in the control system, to the calculation of the phase-error variance with the nonzero loop delay time, a high-accuracy analytic expression phase-error variance is obtained. The linewidth requirement with the nonnegligible loop delay time for phase-shift-keying (PSK) homodyne detection is obtained as delta nu =2.04*10/sup -3// tau where delta nu (hertz) is beat linewidth and tau (seconds) is the loop delay time. The linewidth requirement with small delay time approaches delta nu =6.2*10/sup -4/ R/sub b/ where R/sub b/ (bits-per-second) is the system bit rate. Results were confirmed by a 10-GB/s optical PSK homodyne detection experiment using external cavity laser diodes. Receiver sensitivity degradations due to loop delay time and beat linewidth are in good agreement with theoretical results.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Subtotal scapulectomy as the treatment for scapular tumour in the dog: a report of six cases (2006)

The medical records of six dogs treated by sub-total scapulectomy for tumours involving the scapula were reviewed. The mean age of dogs in this study was 8 years and 4 months. Clinical signs on presentation included lameness of the affected forelimb and a palpable mass over the scapular area on physical examination. Pre-operative chest and affected forelimb radiographs were taken in most cases in addition to a biopsy. Subtotal scapulectomy was performed, ensuring margins clear of neoplastic tissue of at least 2 cm, preservation of the glenoid cavity and thus retention of the scapulo-humeral joint. On histopathological examination the tumours where diagnosed as chondrosarcoma (one), haemangiosarcoma (two), anaplastic malignant neoplasia (one) and osteosarcoma (one). Limb function was found to be good in all cases postoperatively. Prognosis was related to histopathological diagnosis of the tumour, favourable with chondrosarcoma and poor with the other tumour types.