gebhart/patrepeval huggingface dataset:
Development of Transparent Organic Hole-transporting Materials Using Partially Oxygen-bridged Triphenylamine Skeletons (2017)

m-Benzene-linked derivatives of partially oxygen-bridged triphenylamine were designed and synthesized as transparent hole-transporting materials, which show absorption bands only in the UV region (–425 nm). Vacuum-deposited films of these compounds retain amorphous states even after heating at 160 °C and exhibit good hole mobility in the same order to the directly connected dimer.
THE ECONOMIC IMPACT OF THE RED IMPORTED FIRE ANT ON THE METROPLEXES OF TEXAS (2000)

This research estimates the annual economic impact of the fire ant on key urban sectors in Texas. A study was conducted in 1998-1999 in the 5 metroplexes of Austin, Dallas, Fort Worth, San Antonio and Houston to estimate the costs of controlling and managing fire ants (Lard, et al). This study found that the annual expenditure for fire ant control and management by selected sectors in these metroplexes totaled more than $581 million. The total annual expense by sector amounted to $526 million for households, $29 million for golf courses, $25 million for schools, and $0.6 million for cities. These annual cost figures do not include all urban costs or costs borne by electrical utility companies, communication firms and cable companies. These results can be used to assess damages and estimate the potential costs and benefits of control and management programs, such as the community-based effort underway as part of the Texas Fire Ant Initiative.
WISP1 Is a Novel Adipokine Linked to Inflammation in Obesity (2014)

WISP1 (Wnt1-inducible signaling pathway protein-1, also known as CCN4) is a member of the secreted extracellular matrix–associated proteins of the CCN family and a target gene of the Wingless-type (WNT) signaling pathway. Growing evidence links the WNT signaling pathway to the regulation of adipogenesis and low-grade inflammation in obesity. We aimed to validate WISP1 as a novel adipokine. Human adipocyte differentiation was associated with increased WISP1 expression and secretion. Stimulation of human macrophages with WISP1 led to a proinflammatory response. Circulating WISP1 and WISP1 subcutaneous adipose tissue expression were regulated by weight changes in humans and mice. WISP1 expression in visceral and subcutaneous fat tissue was associated with markers of insulin resistance and inflammation in glucose-tolerant subjects. In patients with nonalcoholic fatty liver disease, we found no correlation among disease activity score, liver fat content, and WISP1 expression. Insulin regulated WISP1 expression in adipocytes in vitro but had no acute effect on WISP1 gene expression in subcutaneous fat tissue in overweight subjects who had undergone hyperinsulinemic clamp experiments. The data suggest that WISP1 may play a role in linking obesity to inflammation and insulin resistance and could be a novel therapeutic target for obesity.
Reinforcement Learning for Multi-Objective Optimization of Online Decisions in High-Dimensional Systems (2019)

This paper describes a purely data-driven solution to a class of sequential decision-making problems with a large number of concurrent online decisions, with applications to computing systems and operations research. We assume that while the micro-level behaviour of the system can be broadly captured by analytical expressions or simulation, the macro-level or emergent behaviour is complicated by non-linearity, constraints, and stochasticity. If we represent the set of concurrent decisions to be computed as a vector, each element of the vector is assumed to be a continuous variable, and the number of such elements is arbitrarily large and variable from one problem instance to another. We first formulate the decision-making problem as a canonical reinforcement learning (RL) problem, which can be solved using purely data-driven techniques. We modify a standard approach known as advantage actor critic (A2C) to ensure its suitability to the problem at hand, and compare its performance to that of baseline approaches on the specific instance of a multi-product inventory management task. The key modifications include a parallelised formulation of the decision-making task, and a training procedure that explicitly recognises the quantitative relationship between different decisions. We also present experimental results probing the learned policies, and their robustness to variations in the data.
Toga virus‐like particles in acute liver failure attributed to sporadic non‐A, non‐B hepatitis and recurrence after liver transplantation (1992)

Toga virus-like particles (typically 60-70 nm: enveloped with small surface spikes) were detected in the native hepatectomy specimens in 7 of 18 patients grafted for acute liver failure attributed to sporadic non-A, non-B hepatitis and in 2 patients grafted for fulminant hepatitis attributed to anti-epileptic drug hepatotoxicity. These particles were not detected in the hepatectomies from 12 other patients grafted for other causes of acute liver failure, 12 for various chronic liver diseases, and 2 histologically normal livers. Acute hepatic failure, characterized histologically by severe haemorrhagic necrosis, developed 7 days after grafting in 5 patients, all in the non-A, non-B group with toga virus-like particles in native liver. Similar virus-like particles were detected in all grafts and were in greater abundance than in the native livers. The agent may be novel because pre- and post-grafting sera were negative for antibodies against representative panels of arboviruses and in first and second generation antibody tests for hepatitis C virus.
Massive Lymphocyte-Mediated Apoptosis during the Early Stage of Pseudopelade (1986)

The early evolving lesions of the hair follicles are described in pseudopelade, a type of cicatricial alopecia where clues for the diagnosis of lupus erythematosus or lichen plano-pilaris are lacking. A sudden and synchronized cell death of all the cells of the epithelial sheaths of the hair follicles occurs and is associated with a dense infiltration by lymphocytes. The epidermis remains uninvolved. This unique aspect is most probably related to the mechanism of apoptosis. Its intensity and extension are much more pronounced than in lichen planus and in lupus erythematosus. Pathogenesis of at least some cicatricial alopecias could therefore be related to massive apoptosis without evident and close relationship with the classical etiologies, i.e. lichen planus and lupus erythematosus.
Very low loss ion implanted planar waveguides in lead germanate glass (1993)

Ion implantation has been used to produce very low loss optical waveguides in lead germanate glass samples. There is an increase in the refractive index of 0.35% for the given ion beam parameters. The loss can be as low as 0.15 dB/cm after thermal annealing.
Design, Synthesis, and Evaluation of a Potent Mechanism-Based Inhibitor for the TEM .beta.-Lactamase with Implications for the Enzyme Mechanism (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDesign, Synthesis, and Evaluation of a Potent Mechanism-Based Inhibitor for the TEM .beta.-Lactamase with Implications for the Enzyme MechanismKazuyuki Miyashita, Irina Massova, Pascale Taibi, and Shahriar MobasheryCite this: J. Am. Chem. Soc. 1995, 117, 45, 11055–11059Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ja00150a003https://doi.org/10.1021/ja00150a003research-articleACS PublicationsRequest reuse permissionsArticle Views375Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthetic vertical seismic profile (1981)

Abstract A time-domain model has been developed for calculation of a synthetic vertical seismic profile (SVSP) from a sonic log recorded in a borehole. The SVSP has proven to be extremely useful in the interpretation of seismic data since it allows the interpreter to analyze the propagation of the source pulse through the earth in depth as well as time.Previously, the synthetic seismogram technique allowed analysis of the earth's response to the source pulse at the surface only. However, the development of the SVSP allows insight into the entire wave propagation problem since the calculation shows the response of the earth to the source pulse at any depth point in the subsurface. For example, the synthetic seismogram can be used to identify an event on the seismic section as a multiple, whereas, the SVSP cannot only identify a multiple, but can also show which path the source pulse took through the earth layers to create the multiple.The SVSP can also be used to analyze the change in character of the source pulse due to the layering effect of the earth, for example, effects of a thin bed sequence; to study amplitude variations due to transmission losses; and to examine the effects of different source pulse bandwidths on the final surface seismogram, etc. As interpreters gain experience in analyzing the SVSP, many more applications are expected to appear.
Self-Assembly versus Directed Assembly of Nanoparticles via Pulsed Laser Induced Dewetting of Patterned Metal Films (2011)

A nanoscale, synthetic perturbation was all that was required to nudge a natural, self-assembly process toward significantly higher order. Metallic thin film strips were transformed into nanoparticle arrays by nanosecond, liquid-phase dewetting. Arrays formed according to an evolving Rayleigh-Plateau instability, yet nanoparticle diameter and pitch were poorly controlled. However, by patterning a nanoscale sinusoid onto the original strip edge, a precise nanoparticle diameter and pitch emerged superseding the naturally evolving Rayleigh-Plateau instability.
Closed-form analysis of linearly constrained CMA-based blind multiuser detector (2000)

In this letter, we present a performance analysis of the blind adaptive multiuser detector (MUD) proposed in Miguez and Casredo (1998), which is based on the linearly constrained constant modulus (LCCM) criterion. Global convergence of the algorithm with additive white Gaussian noise (AWGN) is proved and two approximate closed-form solutions of the optimum tap-weight vector are derived. Also the validity of analysis is demonstrated by comparing analytical results with simulated results.
Pheromone based transportation scheduling system for the multi-vehicle routing problem (2003)

We propose a novel and fast method, named "pheromone based transportation scheduling system" (PBTS), to obtain feasible solution for the multi-vehicle routing problem. It is a method inspired by a communication mechanism of living organisms such as ants and bees which communicate with each other and organize the cluster using pheromones. In PBTS, each transportation agent autonomously and independently searches its own route as the partial solution of the vehicle routing problem, where the imitated pheromone is effectively used to dissolve the duplications of customers between routes of agents. Computer simulations show that the PBTS can generate good solutions comparably to the one generated by a genetic algorithm in shorter time.
Use of satellite observed cloud patterns for the analysis of 500-mb level in tropics (1971)

This paper illustrates the use of a quasi objective scheme suggested by Nagle etal. (1970), to utilize satellite observed cloud patterns for the analysis of 500 mb height field in the areas of sparse network in the tropics. The scheme based on, only satellite pictures, provides a very useful first guess field for the machine analysis and excellent guide, especially over areas of scanty data, for the conventional analyst. The basic limitations of the scheme for its use over the tropice and future studies required for its best exploitation have also been briefly discussed.
Enforceable security policies (2000)

A precise characterization is given for the class of security policies enforceable with mechanisms that work by monitoring system execution, and automata are introduced for specifying exactly that class of security policies. Techniques to enforce security policies specified by such automata are also discussed.
Single Mode Fiber Optic Transceiver Using Short Wavelength Active Devices In Long Wavelength Fiber (1990)

Presently, single mode optical fiber technology is being utilized in systems to supply telephone service to the subscriber. However, in an attempt to be competitive with copper based systems, there are many development programs underway to determine the most cost effective solution while still providing a service that will either satisfy or be upgradeable to satisfy the demands of the consumer for the next 10 to 20 years. One such approach is to combine low cost laser transmitters and silicon receivers, which have been developed for the "compact disc" industry, with fiber that operates in the single mode regime at 1300 nm. In this paper, an optical transceiver will be presented, consisting of a compact disc laser, a silicon detector and a single mode coupler at 1300 nm. A possible system layout is presented which operates at 780 nm bi-directionally for POTS and upgradeable to 1300 nm for video services. There are several important design criteria that have to be considered in the development of such a system which will be addressed. These include: 1. Optimization of coupled power from laser to fiber while maintaining stable launched conditions over a wide range of environmental conditions. 2. Consideration of the multimode operation of the 1300 nm single mode fiber while operating in the 780 nm wavelength region. 3. Development of a low cost pseudo-wavelength division multiplexer for 1300 nm single mode/780 nm multimode operation and a low cost dual mode 50/50, 780 nm splitter using 1300 nm fiber. Details will be given of the design criteria and solution in terms of optimized design. Results of the performance of several prototype devices will be given with indications of the merits of this approach and where further development effort should be applied.
Fiberglas reinforced plastics (1954)

Multisystem inflammatory syndrome in children (MIS-C) is a newly defined hyperinflammatory disease linked to antecedent coronavirus disease 2019. Patients with MIS-C present with various symptoms, and ocular findings such as mild bilateral conjunctivitis are relatively common. However, detailed descriptions of severe ocular reports associated with MIS-C are scarce in the current literature. Here we report a case of MIS-C in a Japanese boy, with severe eye manifestations in the form of anterior scleritis as the primary MIS-C symptom. Detailed ocular examinations by ophthalmologists may be key for clarifying the pathophysiology of MIS-C.
TinyGAN: Distilling BigGAN for Conditional Image Generation (2020)

Generative Adversarial Networks (GANs) have become a powerful approach for generative image modeling. However, GANs are notorious for their training instability, especially on large-scale, complex datasets. While the recent work of BigGAN has significantly improved the quality of image generation on ImageNet, it requires a huge model, making it hard to deploy on resource-constrained devices. To reduce the model size, we propose a black-box knowledge distillation framework for compressing GANs, which highlights a stable and efficient training process. Given BigGAN as the teacher network, we manage to train a much smaller student network to mimic its functionality, achieving competitive performance on Inception and FID scores with the generator having $16\times$ fewer parameters.
A framework for abstract 3D visualization (2002)

This paper describes a package, PLUM, we have developed for visualizing abstract data in three dimensions. We are particularly interested in visualizing information about programs, both static and dynamic, but the package should have a more general applicability. The package provides a framework to support a wide variety of different 3D visualization techniques, many of which have been implemented. The package also provides support for 3D graph layout using a variety of different layout heuristics.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Association between Cellular-Telephone Calls and Motor Vehicle Collisions (1997)

The use of cellular telephones in motor vehicles is associated with a quadrupling of the risk of a collision during the brief time interval involving a call. Decisions about regulation of such telephones, however, need to take into account the benefits of the technology and the role of individual responsibility.
GenApp, Containers and Abaco (2019)

GenApp is an NSF-funded framework for rapid generation of applications including feature rich science gateways. GenApp is being successfully used to produce science gateways wrapping scientific programs. Its organization is designed to simplify the process of adding new features and capabilities to generated applications. A limited set of definition files define application generation. To bring a new executable into GenApp, one creates a single "module" definition file. The executable must run on some compute resource accessible by the generated application. Installations of the executable on target resources may be complex. To simplify portability of execution, we introduce automatic containerization of defined modules and integration of container execution. Abaco is an NSF-funded web service and distributed computing platform providing functions-as-a-service (FaaS) to the research computing community. Abaco implements functions using the Actor Model of concurrent computation. We introduce GenApp integration of execution with Abaco as a resource.
Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene (2004)

Adenosine to inosine editing of mRNA from the human 5-HT2C receptor gene (HTR2C) occurs at five exonic positions (A-E) in a stable stem-loop that includes the normal 5' splice site of intron 5 and is flanked by two alternative splice sites. Using in vitro editing, we identified a novel editing site (F) located in the intronic part of the stem-loop and demonstrated editing at this site in human brain. We have shown that in cell culture, base substitutions to mimic editing at different combinations of the six sites profoundly affect relative splicing at the normal and the upstream alternative splice site, but splicing at the downstream alternative splice site was consistently rare. Editing combinations in different splice variants from human brain were determined and are consistent with the effects of editing on splicing observed in cell culture. As RNA editing usually occurs close to exon/intron boundaries, this is likely to be a general phenomenon and suggests an important novel role for RNA editing.
Redox-photosensitized reactions. 11. Ru(bpy)32+-photosensitized reactions of 1-benzyl-1,4-dihydronicotinamide with aryl-substituted enones, derivatives of methyl cinnamate, and substituted cinnamonitriles: electron-transfer mechanism and structure-reactivity relationships (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRedox-photosensitized reactions. 11. Ru(bpy)32+-photosensitized reactions of 1-benzyl-1,4-dihydronicotinamide with aryl-substituted enones, derivatives of methyl cinnamate, and substituted cinnamonitriles: electron-transfer mechanism and structure-reactivity relationshipsChyongjin Pac, Yoji Miyauchi, Osamu Ishitani, Mikio Ihama, Masahide Yasuda, and Hiroshi SakuraiCite this: J. Org. Chem. 1984, 49, 1, 26–34Publication Date (Print):January 1, 1984Publication History Published online1 May 2002Published inissue 1 January 1984https://pubs.acs.org/doi/10.1021/jo00175a006https://doi.org/10.1021/jo00175a006research-articleACS PublicationsRequest reuse permissionsArticle Views1198Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Complete sequence characterization of isolates of Getah virus (genus Alphavirus, family Togaviridae) from China (2008)

Ten virus isolates belonging to species Getah virus (GETV) have been obtained during surveys for arboviruses in China since 1964. Seven of these isolates (YN0540, YN0542, SH05-6, SH05-15, SH05-16, SH05-17 and GS10-2) were obtained during the current study. The full-length sequences of three Chinese isolates (M1, isolated in 1964; HB0234, isolated in 2002; YN0540, isolated in 2005) were determined. The full-length sequences of these isolates were respectively 11 696, 11 686 and 11 690 nt, and showed more than 97 % intraspecies identity. Deletions were found in the capsid protein of strain M1 and non-structural protein nsP3 of strain HB0234. The E2 gene and 3' UTR of all ten isolates were also characterized. The E2 gene of the Chinese GETV isolates showed nucleotide sequence identities of 98-100 % when compared with other GETV isolates. In the 3' UTR of the Chinese isolates, an insertion of 10 consecutive adenine residues (nt 189-198) appeared in strain M1, and 9 or 3 consecutive adenines were found towards the 3' end of the third RES in strains SH05-6 and SH05-15, respectively. The 3' UTRs of the Chinese isolates showed a deletion between positions 45 and 54 and nucleotide transitions at positions 43, 64 and 148. Sequence and phylogenetic analyses showed that there was a relatively high degree of conservation among GETV isolates. The isolation of GETV from various provinces in China and also in Russia and Mongolia (including regions of the northern tundra) are an indication of changes in the world distribution of this re-emerging virus.
Analysis of Host-Cell Responses by Immunoblotting, ELISA, and Real-Time PCR (2012)

Intracellular responses to external pathogens/stimuli are crucial to the host's response to infection. The methods used to analyse these responses fall into many categories. Activation of proteins as part of a signal cascade can be screened for using conventional immunoblotting techniques or immunoprecipitation to identify the presence of modified proteins or protein complexes. Transcription factor activity can be screened for by EMSA or ELISAs to identify DNA binding of these factors. Finally, expression of activated genes can be quantified using real-time PCR methods. Here, we will show how to perform these assays and discuss the relative merits of each.