gebhart/patrepeval huggingface dataset:
Guanylhydrazones with potential antileukemic activity. 2. Synthesis and structure-activity relationships of analogs of 4,4'-diacetyl-N,N'-diphenylurea bis(guanylhydrazone) (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGuanylhydrazones with potential antileukemic activity. 2. Synthesis and structure-activity relationships of analogs of 4,4'-diacetyl-N,N'-diphenylurea bis(guanylhydrazone)W. Korytnyk, N. Angelino, C. Dave, and L. CaballesCite this: J. Med. Chem. 1978, 21, 6, 507–513Publication Date (Print):June 1, 1978Publication History Published online1 May 2002Published inissue 1 June 1978https://pubs.acs.org/doi/10.1021/jm00204a002https://doi.org/10.1021/jm00204a002research-articleACS PublicationsRequest reuse permissionsArticle Views350Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Study of the Structural Design and Capacitance Characteristics of Fabric Sensor (2011)

In response to the problem for non-washable and poor taking comfortable characterizations of smart electronic fabrics at present, two different organizational structures of fabric sensors with plain weave and double weave are designed. The basic principle of design of fabric sensor is: the core-spun yarn made of metal wire is used as core wire, the structural unit with capacitor function is built by interweaving warp with weft, and the induction of fabric to external pressure is reflected by testing changes in capacitance of fabric. The models of equivalent electronic circuits of two fabric sensors with plain weave and double weave are analyzed, and the relationships between area and capacitance characteristics of fabric sensor are discussed. The results show that: the larger the fabric area, the greater the capacitance, and the capacitance of 36cm 2 fabric is maximum with 100Hz test frequency; under the condition of the same area and test frequency, the capacitance of plain weave fabric is greater than that of double-layer fabric under no pressure, but the increasing rate of capacitance of double-layer fabric is larger than that of plain weave fabric under the same pressure.
X-ray excited optical luminescence studies or ZnS and ZnO nanostructures. (2006)

Due to their potential as optoelectronic devices, luminescing nanostructures have been among the most studied in the recent past. Room-temperature UV lasing has been demonstrated in ZnO nanowires. For highly asymmetric wurtzite structures, the orientation of the emitting luminescent dipole with respect to the excited state polarization can play a role in the luminescence yield. ZnS is an important, wide bandgap (E{sub g} = 3.54 eV for the thermodynamically stable zinc blende form at room temperature) II-VI semiconductor. It has been developed for a number of applications including UV light-emitting diodes, injection lasers and phosphors. In this presentation we will discuss results of a study on ZnS nanostructurees using synchrotron-radiation-based, x-ray-excited optical luminescence (XEOL). Results on ZnO will be presented elsewhere. The experimental approach has been described previously. All measurements were performed on beamline 4-ID-C at the Advanced Photon Source. Samples were prepared by a high-temperature growth technique described previously. Briefly, ZnS powder was placed in the center of a horizontal alumina tube upstream of a Si wafer, which was covered with 2 nm thiol-capped gold nanoparticles (used to catalyze the growth). The tube was heated to 1000 C while an Ar/H{sub 2} gas mixture flowed through the tube. Thismore » process resulted in the formation of nanoribbons of lengths in the range 10-100 {micro}m and widths less than 100 nm. The samples were characterized by high-resolution TEM images, which showed large areas of hexagonal wurtzite structure interspersed by nanosized regions with cubic sphalerite structure. Using XEOL, we have determined the local phase of the luminescing sites in ZnS nanowires. The inset of the accompanying figure shows the temperature-dependent optical spectrum obtained when exciting the nanowires with 1100 eV x-rays. There are three main peaks: a band-edge, exiton state at 338 nm, a defect-related emission at 430 nm, and a Au-related feature at 520 nm. (Au is used as a catalyst to grow the wire.) By monitoring the yields of each of these peaks as a function of energy at the Zn L edge, we are able to determine the phase associated with them. The x-ray fluorescence (XRF) and 338 nm peak has a wurtzite signature, while the 430 and 520 nm curves resemble sphalerite. These results show that the 338 nm exciton state originates in the dominant, wurtzite phase of the wire, while the other two peaks occur in dilute ({approx}0.1%) regions of sphalerite.« less
Distributed Congestion Control Approaches for the IEEE 802.11p Vehicular Networks (2013)

This article surveys a collection of representative congestion control approaches for the IEEE 802.11p vehicular network. Challenges remaining in the current literature are concluded. We then propose a novel distributed multi-priority congestion control method to maximize the transmission opportunities for the highest priority traffics while keeping the collision probability at a low level. Open issues for the future work on the congestion control approach design are drawn at the end of this article.
Soybean (Glycine max) Response to Glyphosate and Soybean Cyst Nematode (Heterodera glycines)<sup>1</sup> (2002)

Field observations in Ohio suggested a possible interaction between soybean cyst nematode (SCN) and glyphosate in Countrymark 316 soybean, a transgenic glyphosate-resistant (R) variety that also expresses SCN resistance derived from ‘PI88788’ soybean. To investigate this possible interaction under controlled conditions, greenhouse experiments were conducted in which Countrymark 316 (R) and Corsoy 79 (S = susceptible to glyphosate and SCN) soybean root and shoot weights were measured in response to three concentrations of race 3 SCN inoculum and five glyphosate doses. Experiments were conducted in which glyphosate was applied 9, 18, or 27 d after inoculation (DAI). Data from SCN treatments in the (S) soybean experiments were regressed on glyphosate dosage and fit to a log-logistic dose–response model. SCN–glyphosate interaction in the (S) soybean variety reduced root dry weight of SCN-inoculated plants 6% compared with noninoculated plants when 1.0 kg/ha glyphosate was applied 18 DAI. The most significant interaction of SCN and glyphosate in the (S) variety occurred when glyphosate was applied 27 DAI; the glyphosate dose required to reduce shoot fresh weight 25% was 0.55 kg/ha in the noninoculated control compared with 0.32 kg/ha in plants inoculated with 1,000 SCN eggs/200 cm3 soil. Glyphosate rates of 0.84 and 1.69 kg/ha reduced root dry weights of Countrymark 316 (R) soybean 10 to 13% at the 18 DAI application timing only. Inoculation with SCN reduced shoot fresh weight of (R) soybean 8 to 29% across all experiments, but there was no interaction of glyphosate and SCN in (R) soybean.Nomenclature: Glyphosate; soybean, Glycine max (L.) Merr. ‘Countrymark 316’ and ‘Corsoy 79’; soybean cyst nematode, Heterodera glycines Ichinohe.Additional index words: Herbicide–nematode interaction, integrated pest management.Abbreviations: DAI, days after inoculation; EPSPS, 5-enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19); GR25, dose required to reduce root or shoot growth by 25%; I50, dose corresponding to biomass halfway between upper- and lower-response limits; POST, postemergence; R, glyphosate SCN resistant; S, glyphosate SCN susceptible; SCN, soybean cyst nematode.
Cerebral Ischemia and Reperfusion: The Pathophysiologic Concept as a Basis for Clinical Therapy (2004)

The ischemic penumbra has been documented in the laboratory animal as severely hypoperfused, nonfunctional, but still viable brain tissue surrounding the irreversibly damaged ischemic core. Saving the penumbra is the main target of acute stroke therapy, and is the theoretical basis behind the reperfusion concept. In experimental focal ischemia, early reperfusion has been reported to both prevent infarct growth and aggravate edema formation and hemorrhage, depending on the severity and duration of prior ischemia and the efficiency of reperfusion, whereas neuronal damage with or without enlarged infarction also may result from reperfusion (so-called reperfusion injury). Activated neutrophils contribute to vascular reperfusion damage, yet posthypoxic cellular injury occurs in the absence of inflammatory species. Protein synthesis inhibition occurs in neurons during reperfusion after ischemia, underlying the role that these pathways play in prosurvival and proapoptotic processes that may be differentially expressed in vulnerable and resistant regions of the reperfused brain tissue. Ischemia-induced decreases in the mitochondrial capacity for respiratory activity probably contribute to the ongoing impairment of energy metabolism during reperfusion and possibly also the magnitude of changes seen during ischemia. From these experimental data, the concept of single-drug intervention cannot be effective. Further experimental research is needed, especially of the study of biochemical markers of the injury process to establish the role of several drugs.
Supercritical fluid chromatography with packed columns : techniques and applications (1998)

Determination of solubility data with on-line packed column supercritical fluid chromatography chemical basis for the instrumentation used in packed column supercritical fluid chromatography analytical and preparative carbon dioxide chromatography with automated pressure control and different detectors packed column supercritical fluid chromatography - evaporative light scattering detection packed capillary column supercritical fluid chromatography using neat carbon dioxide selectivity tuning in packed column supercritical fluid chromatography subcritical fluid chromatography with organic modifiers on octadecyl packed columns - recent developments for the analysis of high molecular organic compounds chiral chromatography using sub- and supercritical fluids enantiomer separation by sub- and supercritical fluid chromatography on rationally designed chiral stationary phases applications of packed column supercritical fluid chromatography in the development of drugs packed column supercritical fluid chromatography in the development of polymer additives fractionation of polymer homologs with packed column supercritical fluid chromatography the use of supercritical fluids in environmental analysis preparative supercritical fluid chromatography - grams, kilograms, and tons production of high purity n-3 fatty acid-ethyl esters by process scale supercritical fluid chromatography.
ANTIBODIES TO A NOVEL T CELL ANTIGEN, TIRC7, BLOCK SELECTIVELY TYP 1 BUT NOT TYP 2 T-CELL ACTIVATION AND PROLONGS ALLOGRAFT SURVIVAL (1998)

30 T-cell activation requires additional costimulatory signals provided by receptor-ligand interactions between APC and T-cell membrane proteins. The absence of costimulatory signals was shown to result in T cell unresponsiveness and anergy. Although certain information exists, considerable evidence indicate that additional unknown molecules are involved in T-cell activation. In an attempt to identify novel genes induced during T-cell activation, we utilized Differential Display Reverse Transcription PCR method and cloned a novel membrane protein, named TIRC7, from activated human T cells. The kinetics of expression shows that the 2.5 kb transcript undergoes a transient upregulation upon 24 h T-cell alloactivation that is prevented by addition of Cyclosporin A. Anti-TIRC7 specific antibodies localized TIRC7 protein in the membrane fraction of human lymphocytes by Western blot analysis and confocal microscopy. Although TIRC7 was found in little amounts in cytosolic fractions no secreted TIRC7 protein could be detected in supernatants. Blocking of TIRC7 with specific antibodies efficiently prevented both, proliferation and Th1 subset specific cytokine production in mitogen activated cultures, whereas Th2 cytokine production remained unchanged. rIL-2 reverses anti-TIRC7 antibody induced inhibition, indicating that the modulation of the of TIRC7 mediated costimulatory signal results in T-cell anergy. In vivo, anti-TIRC7 antibody treatment exhibited significantly prolonged allograft survival of kidneys transplanted from WF to LEW rats (4/5 rats are still alive after >4 weeks), whereas control serum(n=5) did not affect survival rate (5/5 <7days). In conclusion, blocking of TIRC7 reveals inhibition of T-cell response to antigen in vitro andin vivo, indicating that TIRC7 protein provides costimulatory signals upon T-cell activation and may serve as a novel target for further immunomodulatory interventions.
Self-phase modulation in hybridly mode-locked CW dye lasers (1985)

Largely asymmetric spectra are observed for ultrashort light pulses from a synchronously and passively mode-locked CW rhodamine 6G dye laser, with relatively high intra-cavity intensity. The spectral shape shows a broad wing on the long-wavelength side alone. When the asymmetric spectrum occurs, the conventional SHG intensity auto-correlation trace shows exponential-like long tails. Further, the temporal characteristics of the mode-locked pulses, including both the shape and phase, are also examined by a new method of SHG autocorrelation, where the SH output is spectrally resolved. These experimental results are explained with self-phase modulation (SPM) process due to the optical Kerr effect in a mixed dye jet stream inside the laser cavity. The main observed characteristics are in reasonable agreement with the theoretical expectation from the slow SPM mechanism, where the pulse width is much shorter than the relaxation time τ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</inf> of refractive index. The measured nonlinear refractive index n <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> and τ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</inf> also support the above interpretation.
[A recommendable standard protocol of adult male circumcision with the Chinese Shang Ring: outcomes of 328 cases in China]. (2009)

The standard protocol of adult male circumcision with the Shang Ring has the advantages of short operation time, slight pain, low rate of complications, and high satisfaction and acceptance of the patients. Strict standardization of the surgical protocol can maximize its clinical advantages for adult male circumcision.
The optimal gradient matching method: application to X-SAR and Magellan stereo images (1998)

The authors propose a new method for improving terrain reconstruction from SAR stereo images. The method is based on preprocessing the original images by employing an optimal filter which suppresses speckle noise and enhances relief structures that are afterwards used by the matching process. In tests on X-SAR images of a rugged terrain in the Austrian Alps and Magellan images of Venus' surface, the preprocessing technique delivered better matching results than the conventional use of original SAR images.
Highly Responsive Hydrogel Scaffolds Formed by Three-Dimensional Organization of Microgel Nanoparticles (2007)

We present a robust and straightforward method for fabricating remarkably responsive hydrogel scaffolds consisting of submicron-sized microgel particles. We demonstrate that the microgel particles assemble either through bridging or depletion interactions to yield a structure that swells or deswells at a macroscopic level in much shorter times as compared to a bulk polymer gel of similar characteristics. This approach offers a new way of fabricating functional hydrogel scaffolds with controllable responsiveness to applied stimuli and excellent loading capability for a wide variety of materials, irrespective of chemistry, size, and shape.
Life span well‐being (2005)

Abstract This chapter, rooted in life span developmental research and theory, examines domains of subjective well‐being: emotional, social, and psychological. What is the impact of these domains on the learner's experience of education? It invites the reader to consider implications for learning through the use of learners' narratives.
Online Heuristic Selection in Constraint Programming (2009)

This paper presents our first attempt to apply Support Vector Machines to the problem of automatically tuning CP search algorithms. More precisely, we exploit instances features to dynamically adapt the search strategy of a CP solver in order to more efficiently solve a given instance. In these preliminary results, adaptation is restricted to restart points, and the number of times the strategy changes is also restricted. We report very encouraging results where our adaptation outperforms what is currently considered as one of the state of the art dynamic variable selection strategy. 1
<title>512x512 WISP (wideband infrared scene projector) arrays</title> (1996)

An addressable mosaic array of resistively heated microbridges offers much flexibility for infrared scene simulations. In the Wide Band Infrared Scene Projector program, Honeywell has demonstrated high yield arrays up to size 512 X 512 capable of room temperature operation for a 2 band infrared projection system being designed and built by Contraves Inc. for the Wright Laboratory Kinetic Kill Vehicle Hardware In-the-Loop Simulator facility at Eglin Air Force Base, FL. The arrays contain two different pixel designs, one pixel designed for kHz frame rates and high radiance achieved at a power level of 2.5 mWatts/pixel and the other pixel designed for more moderate 100 Hz frame rates at lower radiance and at maximum power levels of 0.7 mWatts/pixels. Tests on arrays and pixels have demonstrated dynamic ranges up to 850:1, radiance rise times on the order of 2 mseconds, and broadband pixel emissivities in the range of 70%. Arrays have been fabricated with less than 0.1% pixel outages and no row or column defects. These arrays are mounted in a specialized vacuum assembly containing an IR window, vacuum package, cooling block, and pump out manifold.
Growth, optical characterization, and laser operation of a stoichiometric crystal<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi mathvariant="normal">KYb</mml:mi><mml:mo>(</mml:mo><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">WO</mml:mi></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mo>)</mml:mo></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (2002)

We present our recent achievements in the growing and optical characterization of $\mathrm{KYb}({\mathrm{WO}}_{4}{)}_{2}$ (hereafter KYbW) crystals and demonstrate laser operation in this stoichiometric material. Single crystals of KYbW with optimal crystalline quality have been grown by the top-seeded-solution growth slow-cooling method. The optical anisotropy of this monoclinic crystal has been characterized, locating the tensor of the optical indicatrix and measuring the dispersion of the principal values of the refractive indices as well as the thermo-optic coefficients. Sellmeier equations have been constructed valid in the visible and near-IR spectral range. Raman scattering has been used to determine the phonon energies of KYbW and a simple physical model is applied for classification of the lattice vibration modes. Spectroscopic studies (absorption and emission measurements at room and low temperature) have been carried out in the spectral region near $1 \ensuremath{\mu}\mathrm{m}$ characteristic for the ytterbium transition. Energy positions of the Stark sublevels of the ground and the excited state manifolds have been determined and the vibronic substructure has been identified. The intrinsic lifetime of the upper laser level has been measured taking care to suppress the effect of reabsorption and the intrinsic quantum efficiency has been estimated. Lasing has been demonstrated near 1074 nm with $41%$ slope efficiency at room temperature using a 0.5 mm thin plate of KYbW. This laser material holds great promise for diode pumped high-power lasers, thin disk and waveguide designs as well as for ultrashort (ps/fs) pulse laser systems.
The APTT Monitoring of Heparin - The ISTH/ICSH Collaborative Study (1995)

In an international collaborative study three candidate reference and the local APTT reagent have been tested with lyophilized plasmas containing heparin added in vitro and fresh plasmas from heparinized patients to determine whether it was possible to standardize APTT heparin monitoring. The APTT responses of patients with thrombosis were much less to the same concentrations of heparin so only these plasmas were used to calibrate the reagents. A calibration constant (b) was determined for each local APTT system from the orthogonal regression slope of the patients' and normals' plasmas. Although the calibration was based on relatively limited numbers of patients' plasmas the results gave no consistent indication that this method of analysis with the reference preparations was incorrect. Two of the three candidate reference reagents performed almost equally well and one of these reagents is recommended as the APTT reference preparation. Use of a single b value for a brand of reagent for all laboratories is not advised. Each laboratory must perform its own local calibration. The adoption of a reference APTT reagent together with the use of orthogonal regression analysis would be a useful step to initiate APTT heparin monitoring standardization and to develop safe and effective local therapeutic ranges.
A novel photo-thermal setup for evaluation of absorptance losses and thermal wavefront deformations in DUV optics (2007)

For an assessment of the optical quality of DUV optics, a high-sensitivity wavefront analyzer system based on the Hartmann-Shack principle is employed. The device accomplishes precise on-line monitoring of wavefront deformations of a collimated test beam transmitted through the laser-irradiated site of a sample. Due to the achieved sub-nm resolution, it can be used as an alternative to calorimetric and interferometric measurements for 'at wavelength' testing of optics, e.g. for on-line registration of thermal lensing effects or compaction in fused silica. By recording wavefront distortions of fused silica samples of different thickness and at different fluences the contribution of bulk and surface to the total absorption as well as one- and two-photon effects can be separated.