gebhart/patrepeval huggingface dataset:
The message is the message: designing information technology for inclusiveness and accessibility (2003)

Universal design advocates designing virtual as well as physical environments to be accessible and usable by as many potential users as possible. However, dominant ways of thinking about accessibility and information technology, and the resulting design and implementation practices, tend to create needless barriers to information and opportunities for a large and growing group of technology users. These assumptions and practices are also disabling the development and uses of information technology in general. We describe some technological and barriers to providing universal access to information technology resources for students with disabilities at North Carolina State University. We present research from social sciences and disability studies that suggests insights and alternative models for understanding how and why "disability" is being socially reconstructed on the Web. We end with general suggestions for accessible technology and Web design that can expand possibilities for both technology development and technology users.
An algorithm for the T-countAn algorithm for the T-count (2014)

We consider quantum circuits composed of Clifford and $T$ gates. In this context the $T$ gate has a special status since it confers universal computation when added to the (classically simulable) Clifford gates. However it can be very expensive to implement fault-tolerantly. We therefore view this gate as a resource which should be used only when necessary. Given an $n$-qubit unitary $U$ we are interested in computing a circuit that implements it using the minimum possible number of $T$ gates (called the $T$-count of $U$). A related task is to decide if the $T$-count of $U$ is less than or equal to $m$; we consider this problem as a function of $N=2^n$ and $m$. We provide a classical algorithm which solves it using time and space both upper bounded as $\mathcal{O}(N^m \text{poly}(m,N))$. We implemented our algorithm and used it to show that any Clifford+T circuit for the Toffoli or the Fredkin gate requires at least 7 $T$ gates. This implies that the known 7 $T$ gate circuits for these gates are $T$-optimal. We also provide a simple expression for the $T$-count of single-qubit unitaries.
Webzeitgeist (2013)

Advances in data mining and knowledge discovery have transformed the way Web sites are designed. However, while visual presentation is an intrinsic part of the Web, traditional data mining techniques ignore render-time page structures and their attributes. This paper introduces design mining for the Web: using knowledge discovery techniques to understand design demographics, automate design curation, and support data-driven design tools. This idea is manifest in Webzeitgeist, a platform for large-scale design mining comprising a repository of over 100,000 Web pages and 100 million design elements. This paper describes the principles driving design mining, the implementation of the Webzeitgeist architecture, and the new class of data-driven design applications it enables.
A browser for a public-domain SpeechWeb (2007)

A SpeechWeb is a collection of hyperlinked applications, which are accessed remotely by speech browsers running on end-user devices. Links are activated through spoken commands. Despite the fact that protocols and technologies for creating and deploying speech applications have been readily available for several years, we have not seen the development of a Public-Domain SpeechWeb. In this paper, we show how freely available software and commonly used communication protocols can be used to change this situation.
Platinum Pacemaker Electrodes: Origins and Effects of the Electrode‐Tissue Interface Impedance (1987)

Investigation of the unipolar properties of the paced-evoked response requires special measures to eliminate the post-stimulus potential, and this in turn requires a knowledge of the properties of the electrode-tissue interface which is not supplied by any single source in the literature. We have therefore drawn together published information and some of our own experimental results. The behavior of a particular type of pacemaker electrode was investigated in vitro under a range of conditions. The application of DC potentials revealed an extremely nonlinear voltage-current characteristic with conduction thresholds at about +1 V and -1 V. Small signal AC response to applied voltages well within these values (20 mV pk-pk) was found to be linear when a nonpolarizable counterelectrode was used. Nonlinearities were introduced by the use of a stainless steel counterelectrode. The response of an in vitro model of a paced patient to voltage pulses (amplitude 5 V, duration 0.5 ms) was also investigated. We have made extensive use of previously published work to demonstrate the mechanisms underlying these results and also their relationship to each other. We have concluded with some theoretical comments upon the design requirements for a device to eliminate the post-stimulus afterpotential in order to detect the paced-evoked response.
A Survey of Efficient Hough Transform Methods (1987)

The Hough Transform, HT, has long been recognised as a technique of almost unique promise for shape and motion analysis in images containing noisy, missing and extraneous data. However its widespread adoption in practical systems has been slow due to its computational complexity, the need for large storage arrays and the lack of a detailed understanding of its properties. The aims of Alvey project MMI/IP078 are • the investigation of the properties of HTs • the study of efficient implementations of HTs • the production of a HT hardware device for use in real time industrial inspection systems. • the development of general high level image interpretation strategies which use information derived from the HT. The first three items listed above are being studied at Surrey University in collaboration with Computer Recognition Systems while the final item is under investigation at Heriot Watt University. There has recently been much activity concerned with space and time efficient implementations of HT ideas and this paper presents a survey of this area. Topics covered include the development of new algorithms, the use of optical techniques and the implementation of HTs on novel hardware architectures.
Quantitative analysis of fatty liver ultrasonic images (2002)

Quantitative analysis is a kind of objective diagnosis of fatty liver which can reduce the man made deviation The work presented in this paper focuses on the extraction of diagnostic parameters for the contrast between the liver and the kidney from a few B ultrasonic images Based on the above research,the parameters otherness between the normal and fatty liver was analysed statistically
<title>Surface rugosity and polarimetric analysis</title> (1996)

Reflection polarization properties of a given target, evolve according to its state's surface and to the illumination angle. We have studied the evolution of the polarization given by an iron target the surface of which is progressively debased, the initial surface is polished up to one micron. The polarization is described with the Stokes- Mueller's formalism, from which the matrix exploitation gives us the degree of polarization. We take the measurement of each sample for different angles of incidence. In order to optimize the matrix elements, we reduce the noise by a statistical method. First, the results are presented in a global matrix form, then we present an analysis of the depolarization phenomenon, and we apply some techniques of classification. We also analyze the statistical effect of the polarization transformation on the Poincare sphere.
포장 김치의 지각된 가치가 소비자만족과 재구매 의도에 미치는 영향 (2012)

The purpose of this study is to investigate the relationships between perceived value of Packaged Kimchi and Packaged Kimchi`s consumer satisfaction and repurchase intention, and also to analyze the moderate effect of risk perception in the relationships between those variables. Through which the Packaged Kimchi buying behavior of consumers to understand the specific. In addition to Packaged Kimchi industry servers as the basic material for the study, and Packaged Kimchi companies and their executives for effective marketing strategy was to provide meaningful implications. Empirical analysis of the properties and parameters in order to enhance the feasibility of extracting the information was extracted in previous studies, survey data using SPSS 18.0 statistical package program were analyzed. The analysis results were as follows. First, among the factors of perceived value of Packaged Kimchi, functional value, social value, and economic value had a positive effect on consumer satisfaction and repurchase intention. Second, consumers` satisfaction with Packaged Kimchi had a positive effect on their repurchase intention.
Corrosion‐Induced Contact Failures in Double‐Level Al‐Si‐Cu Metallization (1990)

The contact failure rate for double level Al‐Si‐Cu metallization was found to be much larger than that for double level Al‐Si metallization. The large failure rate in the first case was attributable to the loss of the first conductor in via holes due to pitting corrosion, which was caused at the chemical cleaning stage after the via holes had been opened. The corrosion pits were formed on the grain boundaries of Al alloys, each one accompanied by a particle in its center. The particles were identified as Cu containing precipitates with XMA. Corrosion was accelerated by increasing both Cu concentrations in the Al alloys and annealing temperatures. Some large precipitates with diameters of about 1.0 μm, which is equivalent to the film thickness, were found to exist in Al‐0.9%Si‐1.6%Cu alloys annealed at 450°C. When a large precipitate is situated in a via hole, corrosion occurs. The precipitate and Al on the surface form a galvanic cell, where the precipitate and the Al behave as the cathode and the anode, respectively, resulting in anodic dissolution of the Al. Fuming nitric acid solutions with concentrations of more than 94% prevent the corrosion. Argon ion implantation in Al alloys was found to be effective in preventing corrosion. Annealing after the implantation enhanced the effect drastically. It was found that the Cu concentration on the surface decreases by about one‐half and that the precipitates on the surface are scattered into very small pieces when annealing takes place after implantation.
Efficient secret sharing schemes achieving optimal information rate (2014)

One of the important problems in secret sharing schemes is to establish bounds on the size of the shares to be given to participants in secret sharing schemes. The other important problem in secret sharing schemes is to reduce the computational complexity in both secret distribution phase and secret reconstruction phase. In this paper, we design efficient threshold (n, k) secret sharing schemes to achieve both of the above goals. In particular, we show that if the secret size |s| is larger than max{1 + log <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> n, n(n - k)/(n - 1)}, then ideal secret sharing schemes exist. In the efficient ideal secret sharing schemes that we will construct, only XOR-operations on binary strings are required (which is the best we could achieve). These schemes will have many applications both in practice and in theory. For example, they could be used to design very efficient verifiable secret sharing schemes which will have broad applications in secure multi-party computation and could be used to design efficient privacy preserving data storage in cloud systems.
Use of proteomics to identify highly abundant maternal factors that drive the egg-to-embryo transition (2010)

As IVF becomes an increasingly popular method for human reproduction, it is more critical than ever to understand the unique molecular composition of the mammalian oocyte. DNA microarray studies have successfully provided valuable information regarding the identity and dynamics of factors at the transcriptional level. However, the oocyte transcribes and stores a large amount of material that plays no obvious role in oogenesis, but instead is required to regulate embryogenesis. Therefore, an accurate picture of the functional state of the oocyte requires both transcriptional profiling and proteomics. Here, we summarize our previous studies of the oocyte proteome, and present new panels of oocyte proteins that we recently identified in screens of metaphase II-arrested mouse oocytes. Importantly, our studies indicate that several abundant oocyte proteins are not, as one might predict, ubiquitous housekeeping proteins, but instead are unique to the oocyte. Furthermore, mouse studies indicate that a number of these factors arise from maternal effect genes (MEGs). One of the identified MEG proteins, peptidylarginine deiminase 6, localizes to and is required for the formation of a poorly characterized, highly abundant cytoplasmic structure: the oocyte cytoplasmic lattices. Additionally, a number of other MEG-derived abundant proteins identified in our proteomic screens have been found by others to localize to another unique oocyte feature: the subcortical maternal complex. Based on these observations, we put forth the hypothesis that the mammalian oocyte contains several unique storage structures, which we have named maternal effect structures, that facilitate the oocyte-to-embryo transition.
Digital off-axis holography with a synthetic aperture (2002)

The use of a synthetic aperture is demonstrated as part of an off-axis setup for digital holography. The aperture was constructed from camera recordings at nine different positions. An algorithm to reconstruct object sections, which requires only moderate computer memory, was used. The result shows strongly improved resolution.
Fibroblast growth factor gene expression in AIDS-Kaposi's sarcoma detected by in situ hybridization. (1991)

Biopsy samples from five acquired immune deficiency syndrome (AIDS)-Kaposi's sarcomas and one non-AIDS-associated Kaposi's sarcoma were assayed by in situ RNA hybridization onto paraformaldehyde-fixed, paraffin-embedded skin sections for the presence of two fibroblast growth factor gene transcripts, FGFB and FGF5. FGF5 gene expression was detected in the characteristic Kaposi's sarcoma spindle-shaped cells in the five samples from human immunodeficiency-positive (HIV+) patients. FGFB transcripts were detected in Kaposi's sarcoma cells as well as in epidermis of HIV- and HIV+ patients. These results complement the observations about growth factor gene expression done on Kaposi's sarcoma-derived cell lines, which thus appear to be representative of what happens in vivo. Furthermore, they demonstrate a contrasting expression pattern of FGF5 and FGFB genes, both involved in the growth factor pathogenic cascade leading to Kaposi's sarcoma.
Pattern recognition by audio representation of multivariate analytical data (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPattern recognition by audio representation of multivariate analytical dataEdward S. YeungCite this: Anal. Chem. 1980, 52, 7, 1120–1123Publication Date (Print):June 1, 1980Publication History Published online1 May 2002Published inissue 1 June 1980https://pubs.acs.org/doi/10.1021/ac50057a028https://doi.org/10.1021/ac50057a028research-articleACS PublicationsRequest reuse permissionsArticle Views257Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes (2018)

The mammalian SWI/SNF chromatin remodeling complex is a heterogeneous collection of related protein complexes required for gene regulation and genome integrity. It contains a central ATPase (BRM or BRG1) and various combinations of 10-14 accessory subunits (BAFs for <u>B</u>RM/BRG1 <u>A</u>ssociated <u>F</u>actor<u>s</u>). Two distinct complexes differing in size, BAF and the slightly larger polybromo-BAF (PBAF), share many of the same core subunits but are differentiated primarily by having either AT-rich interaction domain 1A/B (ARID1A/B in BAF) or ARID2 (in PBAF). Using density gradient centrifugation and immunoprecipitation, we have identified and characterized a third and smaller SWI/SNF subcomplex. We termed this complex GBAF because it incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), instead of an ARID protein. In addition to GLTSCR1 or GLTSCR1L, the GBAF complex contains BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM. We observed that GBAF does not contain the core BAF subunits BAF45, BAF47, or BAF57. Even without these subunits, GBAF displayed <i>in vitro</i> ATPase activity and bulk chromatin affinity comparable to those of BAF. GBAF associated with BRD4, but, unlike BRD4, the GBAF component GLTSCR1 was not required for the viability of the LNCaP prostate cancer cell line. In contrast, <i>GLTSCR1</i> or <i>GLTSCR1L</i> knockouts in the metastatic prostate cancer cell line PC3 resulted in a loss in proliferation and colony-forming ability. Taken together, our results provide evidence for a compositionally novel SWI/SNF subcomplex with cell type-specific functions.
Redox properties and evolution of human glutaredoxins (2007)

Glutaredoxins (Grxs) are glutathione-dependent oxidoreductases that belong to the thioredoxin superfamily catalyzing thiol-disulfide exchange reactions via active site cysteine residues. Focusing on the human dithiol glutaredoxins having a C-X-Y-C active site sequence motif, the redox potentials of hGrx1 and hGrx2 were determined to be -232 and -221 mV, respectively, using a combination of redox buffers, protein-protein equilibrium and thermodynamic linkage. In addition, a nonactive site disulfide was identified between Cys28 and Cys113 in hGrx2 using redox buffers and chemical digestion. This disulfide confers nearly five kcal mol(-1) additional stability by linking the C-terminal helix to the bulk of the protein. The redox potential of this nonactive site disulfide was determined to be -317 mV and is thus expected to be present in all but the most reducing conditions in vivo. As all human glutaredoxins contain additional nonactive site cysteine residues, a full phylogenetic analysis was performed to help elucidate their structural and functional roles. Three distinct groups were found: Grx1, Grx2, and Grx5, the latter representing a highly conserved group of monothiol glutaredoxins having a C-G-F-S active site sequence, with clear homologs from bacteria to human. Grx1 and Grx2 diverged from a common ancestor before the origin of vertebrates, possibly even earlier in animal evolution. The highly stabilizing nonactive site disulfide observed in hGrx2 is found to be a conserved feature within the deuterostomes and appears to be the only additional conserved intramolecular disulfide within the glutaredoxins.
A Preliminary Report of an Indirect Fluorescent Antibody Test for Detecting Antibodies to Cysts of<i>Pneumocystis carinii</i>in Human Sera (1972)

Norman, Lois, and Kagan, Irving G.: A preliminary report of an indirect fluorescent antibody test for detecting antibodies to cysts of Pneumocystis carinii in human sera. Am. J. Clin. Pathol. 58: 170–176, 1972. An indirect immunofluorescence screening test for detecting antibodies to Pneumocystis carinii in human serum is described. The antigen used was prepared from isolated pneumocystis cysts separated from human pulmonary tissue. Of 89 sera from patients with confirmed or provisionally diagnosed pneumocystis pneumonia in the United States, 46% were positive. Of 85 sera from healthy contacts in the home or hospital, 14% were positive serologically. None of 50 sera from healthy young Americans was reactive.
Gene for Escherichia coli glycyl-tRNA synthetase has tandem subunit coding regions in the same reading frame. (1982)

Glycyl-tRNA synthetase is one of two Escherichia coli aminoacyl tRNA synthetases which has two different subunits. A 5.1-kilobase pair HindIII chromosomal DNA fragment was isolated, cloned into pBR322 (to give plasmid pTK201), and shown to direct synthesis in maxicells of both subunits (Mr = 35,000 (alpha) and Mr = 65,000 (beta) of glycyl-tRNA synthetase. Locations of alpha- and beta-subunit coding regions were established by introduction of Tn5 insertions into various positions within the 5.1-kilobase pair HindIII segment of pTK201 and by determining the effect of each Tn5 insertion on synthesis of alpha- and beta-subunits and on enzymatic activity. From the Tn5 insertion analysis, regions encoding the NH2 terminus of the alpha-subunit and of the beta-subunit were approximately defined and these regions were sequenced. To locate rigorously the respective NH2-terminal encoding sections in the DNA sequence, NH2-terminal amino acid sequences of alpha- and beta-subunits were established by standard Edman degradations and these sequences were aligned with the DNA sequence. This analysis established the following: 1) coding regions for the subunits are in tandem; 2) a single promoter is used for transcription of both coding sections and the order of transcription is from alpha to beta; 3) in the 500 nucleotides 5' to the start of the alpha-subunit coding section, there is no sequence arrangement like that found for regulatory regions of bacterial amino acid biosynthetic operons; 4) nine nucleotides serve as the spacer between the TAA stop of the alpha- and the ATG start of the beta-subunit coding regions, thus making both coding regions in the same reading frame; and 5) the TAA stop of the alpha-subunit and the next for nucleotides associated with the intersubunit region are complementary to the 3'-end of 16 S rRNA; this arrangement suggests ribosome re-initiation in the spacer region gives balanced synthesis of both subunits.
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data (2013)

A large number of computational methods have been developed for analyzing differential gene expression in RNA-seq data. We describe a comprehensive evaluation of common methods using the SEQC benchmark dataset and ENCODE data. We consider a number of key features, including normalization, accuracy of differential expression detection and differential expression analysis when one condition has no detectable expression. We find significant differences among the methods, but note that array-based methods adapted to RNA-seq data perform comparably to methods designed for RNA-seq. Our results demonstrate that increasing the number of replicate samples significantly improves detection power over increased sequencing depth.