gebhart/patrepeval huggingface dataset:
An Analytical Study of Turbine Disks Incorporating Radially Rotating Heat Pipes (1998)

Abstract In modern aero-engines, a turbine disk is normally cooled by compressed air bled from the engine compressor. A literature survey regarding the turbine disk cooling reveals that although the average air-cooling heat transfer coefficient is generally high, the local heat-transfer coefficient at the disk rim is low. Impinging jet cooling could be used to enhance the heat transfer at the rim, but its implementation is costly. One of the major causes of the high temperature at the rim is the low thermal conductivity associated with the turbine disk material. Based on this understanding, a turbine disk that incorporates radially rotating heat pipes has been introduced. The incorporation of the heat pipe would significantly increase the effective thermal conductance of the disk and spread the heat from the disk rim to a much large surface area, A unique disk design that employs interconnected heat pipe branches is also described for the purpose of cost reduction. To evaluate the effectiveness of the new turbine disk, a simplified analysis based on the one-dimensional and steady-state assumptions is made. The analytical results indicate that a disk that incorporates the heat pipe could reduce the disk rim temperature by more than 300°C, with only a moderate increase in the disk bore temperature. A turbine disk that employs rotating heat pipes is very effective for the disk rim temperature reduction. It also represents a new approach for cooling turbine rotor blades, and could find important applications in advanced gas turbines working at very high inlet temperatures.
REAL-TIME OBJECT DETECTION USING DISTANCE TRANSFORMS (1998)

This paper presents an efficient shape-based object detection method using Distance Transforms (DTs). The proposed method extends previous DT-based matching techniques by using multiple features and a template hierarchy associated with a coarse-to-fine search over the template transformation parameters. Significant speed-up factors are typically obtained when comparing the proposed hierarchical method with an equivalent brute-force technique; wehave measured speed-up gains in the order of two magnitudes. This brings a number of template matching applications which previously required special-purpose correlation hardware onto the realm of the ubiquitous PC. We present results on real-time traffic sign detection to illustrate our approach.
Conservation, localization and expression of HopZ, a protein involved in adhesion of Helicobacter pylori (1999)

From a sarkosyl-insoluble outer membrane fraction prepared from the Helicobacter pylori strain ATCC 43504, 19 proteins could be sequenced N-terminally by Edman degradation. Oligonucleotides were deduced and used for screening of a genomic library. From the isolated genes, five code for different members of a H.pylori outer membrane protein (Hop) family. Among these, the hopZ gene was characterized in more detail. It encodes a protein which was shown to be located at the bacterial surface by immunofluorescence studies. Sequence analysis of the hopZ gene from 15 different H.pylori strains revealed the existence of two alleles and the possible regulation of hopZ expression by slipped-strand mispairing within a CT dinucleotide repeat motif located in the signal-peptide coding region. Among the different strains, the influence of this region on the expression of HopZ was analyzed on a translational level by western blot analysis of bacterial extracts and immunofluorescence studies on intact cells. The protein is expressed only in those strains in which the number of the CT dinucleotide repeats allow for an open reading frame encoding the complete protein. Addionally the function of HopZ was investigated in an adhesion assay. The wild-type strain ATCC 43504 adhered to human gastric epithel cells whereas a knockout mutant strain showed significantly reduced binding to the cells.
The Harvest Smart PReP<sup>TM</sup> system versus the Friadent‐Schütze platelet‐rich plasma kit (2003)

An important reason to improve methods for isolating platelet-rich plasma (PRP) is the potential use of autogenous platelet growth factors. In addition to the Curasan PRP kit (Curasan, Kleinostheim, Germany) and the platelet concentrated collection system (PCCSTM) system, two new methods for the preparation of PRP by the surgeon are now available. This study compared the suitability of these new methods for the preparation of PRP. Whole blood was drawn from 54 healthy donors (33 men and 21 women) aged 23-79 years (38.0 +/- 17.7 years). PRP was prepared from each donor's blood using both the Smart PRePTM system (Harvest Technologies Corporation, Munich, Germany) and the Friadent-Schütze method (PRP kit; Friadent-Schütze, Vienna, Austria). The platelet count in donor whole blood was 276 810 +/- 59 440 /microl. Platelet counts differed significantly between the Smart PRP preparation (1227 890 +/- 312 440 platelets/microl) and the Friadent-Schütze PRP preparation (1440 500 +/- 501 700 platelets/microl) (sign test, P < 0.001). The Smart PRePTM system had a significantly higher collection efficiency (63.4 +/- 7.9%) than the Friadent-Schütze kit (49.6 +/- 13.6%) (sign test, P < 0.001). The leukocyte contents in the two platelet concentrates were similar (Smart PRePTM, 19 261 +/- 8082 platelets/microl; Friadent-Schütze, 21 691 +/- 16 430). Transforming growth factor (TGF)-beta1 and platelet-derived growth factor (PDGF)-AB were higher in the Friadent-Schütze PRP (TGF-beta1, 196.8 +/- 109.6 ng/ml; PDGF-AB, 251.6 +/- 115.4 ng/ml) than in the Smart PRePTM (TGF-beta1, 77.2 +/- 54.8 ng/ml; PDGF-AB, 208 +/- 85.2 ng/ml). The sign test indicated significant differences between the two methods in the concentrations of TGF-beta1 (P < 0.001) and PDGF-AB (P < 0.01). Insulin-like growth factor (IGF)-1 levels in the two PRP preparations were similar (Friadent-Schütze PRP, 72.8 +/- 22.3 ng/ml; Smart PRePTM, 91.4 +/- 21.3 ng/ml). The Smart PRePTM system was superior with respect to ease of handling and preparation time. It also had a significantly higher platelet collection efficiency than the Friadent-Schütze PRePTM kit. The Friadent-Schütze PRP kit offers a slight advantage in the resulting PRP platelet concentration. However, this is easily compensated for in the Smart PRePTM system by reducing the volume of the resulting PRP.
LYDIA (2015)

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Novel drug-delivery systems for patients with chronic rhinosinusitis (2012)

Chronic rhinosinusitis, one of the most common chronic medical complaints in the United States, seems to be increasing in incidence and prevalence, and has a significant impact on quality of life. Topical forms of medical therapy represent an attractive alternative for drug delivery to the nasal cavity and paranasal sinuses. Topical drug delivery has the advantage of directly acting on the site of inflammation, producing a higher concentration at the target site while avoiding systemic side effects. Although considerable research has been undertaken into improving nasal formulations in order to enhance absorption, little attention has so far been directed to upgrading the delivery devices. The aim of this review is to present current knowledge on the novel drug-delivery devices in use in the management of chronic rhinosinusitis patients, and to present the current available knowledge on topical drug penetration into the sinuses using various delivery devices. Additionally, methods used to enhance fluid sinus deposition are presented and the published clinical studies on the results of nebulized antibiotics in the treatment of chronic rhinosinusitis patients are discussed.
Success from Subsea Riserless Well Interventions (2011)

Abstract This paper describes how Statoil, over a period of 10 years, have qualified and implemented Subsea Riserless Light Well Intervention (RLWI) applications as their primary means of intervening in subsea wells. The paper will also demonstrate the value of RLWI in relation to the company's Increased Oil Recovery (IOR) goals. Subsea wells represent the area where least well intervention work has been done, and where the biggest practical and technical challenges also lie. Hence less oil is recovered from subsea completed fields than from those with fixed platforms. RLWI is a cost effective intervention method that allows an operator of subsea wells to increase production and optimize utilization of vessels and rigs. Statoil is a leading exponent of RLWI services, utilizing two specialized and modern vessels on full year contract. A third vessel is currently being considered. The total RLWI activity for 2010 was 671 days, spanning a total of 32 different jobs. This paper will describe the development of these applications from 2000 until today covering a total of 125 individual operations. Statoil has 34 subsea fields, of which 32 are on the Norwegian continental shelf with a total of around 460 individual wells. Light Well intervention has been performed on 11 of these fields. Experience so far indicates that there are no limitations on equipment regarding interface to subsea templates. In this paper the contract philosophy for these services will also be discussed. Further on, the agreement between the different production assets for sharing of resources will also be described. The technical achievements and limitations will be listed and described. Then the needs of the future will be described and prioritized. Finally, the economic benefit and contribution of introducing Riserless Light Well Intervention will also be highlighted. The following three conclusions on RLWI will be elaborated on in this paper: Improves HSE in subsea well interventionsImproves recoveryIntervention cost is cut by more than half compared with anchored rigs and riser systems
Which behavioral and psychological symptoms of dementia are the most problematic? Variability by prevalence, intensity, distress ratings, and associations with caregiver depressive symptoms (2013)

Symptoms revealed as "most problematic" varied by measurement criterion. Common or frequent symptoms are not necessarily the most distressing or most predictive of caregiver depression.
A study of thread migration in temperature-constrained multicores (2007)

Temperature has become an important constraint in high-performance processors, especially multicores. Thread migration will be essential to exploit the full potential of future thermally constrained multicores. We propose and study a thread migration method that maximizes performance under a temperature constraint, while minimizing the number of migrations and ensuring fairness between threads. We show that thread migration brings important performance gains and that it is most effective during the first tens of seconds following a decrease of the number of running threads.
New findings on unconscious versus conscious thought in decision making: additional empirical data and meta-analysis. (2008)

Abstract Ninety-eight Australian students participated in a functional replication of a study published by Dijksterhuis et al. (2006). The results indicated that unconscious thought does not necessarily lead to better normative decision making performance than conscious thought, which is contrary to the results found in Dijksterhuis et al. Since other studies showed a positive, though statistically not significant, effect for unconscious thought, a meta-analysis comprising a total of 17 experiments was conducted. It suggests that there is little evidence for an advantage to normative decision making using unconscious thought. However, a discussion of potential moderators shows that further study would help to identify situations in which unconscious thought is truly helpful and those in which it is not.
Curdlan and Gellan Gum, Bacterial Gel-Forming Polysaccharides, Exhibit Different Effects on Lipid Metabolism, Cecal Fermentation and Fecal Bile Acid Excretion in Rats. (1999)

The effects of curdlan (CD) and gellan gum (GG), bacteria-producing polysaccharides, on lipid concentrations of serum and liver, fecal bile acid composition and intestinal fermentation products were studied in rats fed diets containing cellulose powder (CP), CD or GG at 5% for 4 wk. The cecal weight of the CD group increased significantly as compared to that of the other two groups and the pH of its contents was significantly low. The gastrointestinal transit time in the GG group was significantly shorter than that in the CP and CD groups. No significant inter-group differences were observed in the serum concentrations of total cholesterol and HDL-cholesterol, but a significant decrease was observed in the hepatic total cholesterol concentration of the CD group as compared to that of the CP and GG groups. No significant difference in the total bile acid excretion in feces was observed among the groups, but significantly low values were observed in the proportion of secondary bile acids in the CD group as compared to those of the CP and GG groups. Amounts of short-chain fatty acids (acetic, propionic and butyric acid) and lactic acid in the cecal contents were significantly higher in the CD group than in the other two groups. These results reveal that dietary CD is easily degraded and fermented by intestinal bacteria in the cecum and lowers cholesterol concentration in the liver, while dietary GG shortens the gastrointestinal transit time, suggesting the promotion of evacuation.
Assessing Hail Risk for Property Insurers with a Dependent Marked Point Process (2021)

Abstract Hail risk is among the most challenging perils to insure and property damage due to hailstones has been on the top of the list of annual claims for most non-life insurers. In this article, we present a simple yet flexible statistical model for insurers to assess and manage hail risks from two aspects: analysing the insurance claims arrival pattern upon occurrence of a hailstorm and quantifying the subsequent financial impact of the hailstorm. We formulate the problem using a marked point process where the reporting of insurance claims due to a hailstorm is treated as recurrent events and the claim amounts are viewed as associated marks. Three complications are addressed in model building: the unobserved heterogeneity in claim arrival, the dependence between the event time and the mark and the complex distribution in claim amount. Using a unique data that combine the exposure data from a major US insurer and the radar data from a third-party vendor, we show the proposed method help improve predictive analytics for post-hailstorm claims volume, arrival rate and severity, and thus claim management decisions for the insurer.
IL-4 requirements for the generation of secondary in vivo IgE responses (1991)

IL-4 has been shown to induce B lymphocytes to switch from the expression of membrane IgM to the expression of membrane IgE and to be required for the generation of primary polyclonal and secondary Ag-specific IgE responses in mice. To further define the role of IL-4 in the generation of memory IgE responses, we investigated the ability of a combination of anti-IL-4 and anti-IL-4R mAb to block the generation of secondary IgE responses induced by: 1) a second infection with the nematode parasites Nippostrongylus brasiliensis or Heligmosomoides polygyrus; or 2) injection of anti-IgD antibody-primed mice with anti-IgE antibody. The latter stimulus was designed to induce intrinsic membrane IgE-expressing B cells to differentiate into IgE-secreting cells. Although the IgE responses induced by a second nematode infection were completely inhibited by the combination of anti-IL-4 and anti-IL-4R mAb, anti-IgE antibody-induced IgE responses in anti-IgD primed mice were not inhibited by these antibodies to a large degree. Additional experiments demonstrated that the anti-IgE antibody-induced memory IgE response was dependent on CD4+ T cells but did not involve the low affinity B cell Fc epsilon RII. Taken together, these observations provide evidence that IL-4 is required for virgin B lymphocytes to develop into IgE-expressing cells, but is not required for B cells that express intrinsic membrane IgE to differentiate into IgE-secreting cells in a T-dependent response. Furthermore, these data suggest that secondary IgE responses in the parasite models that we have studied develop from B cells that had not previously switched to the expression of IgE.
Multi-Stage Key Exchange and the Case of Google's QUIC Protocol (2014)

The traditional approach to build a secure connection is to run a key exchange protocol and, once the key has been established, to use this key afterwards in a secure channel protocol. The security of key exchange and channel protocols, and to some extent also of the composition of both, has been scrutinized extensively in the literature. However, this approach usually falls short of capturing some key exchange protocols in which, due to practical motivation, the originally separated phases become intertwined and keys are established continuously. Two prominent examples of such protocols are TLS (with resumption), and Google's recently proposed low-latency protocol QUIC. In this work we revisit the previous security of model of Brzuska et al. (CCS'11) and expand it into a multi-stage key exchange model in the style of Bellare and Rogaway. In our model, parties can establish multiple keys in different stages and use these keys between stages, even to establish the next key. The advantage of using the formalization of Brzuska et al. is that it has been designed with the aim to provide compositional guarantees. Hence, we can, too, give sufficient conditions under which multi-stage key exchange protocols compose securely with any symmetric-key application protocol, like a secure channel protocol. We then exercise our model for the case of the QUIC protocol. Basically, we show that QUIC is an adequately secure multi-stage key exchange protocol and meets the suggested security properties of the designers. We continue by proposing some slight changes to QUIC to make it more amenable to our composition result and to allow reasoning about its security as a combined connection establishment protocol when composed with a secure channel protocol.
In Vivo Imaging of Retinal Hypoxia Using HYPOX-4-Dependent Fluorescence in a Mouse Model of Laser-Induced Retinal Vein Occlusion (RVO) (2017)

HYPOX-4 is an efficient probe capable of imaging retinal hypoxia in vivo, in RVO mice. Future studies will focus on its use in correlating retinal hypoxia to the onset and progression of ischemic vasculopathies.
Effect of 1,25 dihydroxyvitamin D3 and retinoic acid on normal human pluripotent (CFU-mix), erythroid (BFU-E), and myeloid (CFU-C) progenitor cell growth and differentiation patterns. (1986)

The modulatory effect of 1,25 dihydroxyvitamin D3 (vit D) and 13 cis retinoic acid (retinoic acid) on the growth and differentiation of normal human pluripotent stem cell, erythroid, and myeloid progenitor cell growth was studied using semisolid methylcellulose clonal assay. Dose response curves showed that maximal increments of myeloid colony (CFU-C) growth (150%) occurred with vit D at 2 X 10(-9) -2 X 10(-8) M and with retinoic acid (184%) at 1 X 10(-7) M. Vit D caused a 134% increase in macrophage colonies (CFU-M) and a decrease in granulocytic (CFU-G) and granulocyte-macrophage colonies (CFU-GM) (50% and 58%, respectively, as compared to the control). Retinoic acid did not alter the differentiation pattern of myeloid colonies (CFU-M, CFU-G, and CFU-GM). Vit D at 2 X 10(-8) M had an inhibitory effect on BFU-E (62% growth of control) and did not affect CFU-mix growth. Retinoic acid at 10(-7) M did not alter the growth of either BFU-E or of CFU-mix. Cellular differentiation studies in liquid suspension showed that vit D caused a 213% increase in monocyte-macrophages and a 56% and 26% decrease in immature and mature granulocytes, respectively. Retinoic acid caused a marked (79%) decrease in immature granulocytes whereas the percentage of mature granulocytes and monocyte-macrophages was not changed. Assessment of phagocytosis and killing of Candida albicans (C.A.) by cultured monocyte-macrophages and granulocytes exposed to vit D and retinoic acid demonstrated that treated cells had the same capability to phagocytose and kill C.A. as did untreated cells.
Ocular static and dynamic light scattering: a noninvasive diagnostic tool for eye research and clinical practice (2004)

The noninvasive techniques of static and dynamic light scattering are emerging as valuable diagnostic tools for the early detection of ocular and systemic diseases. These include corneal abnormalities, pigmentary dispersion syndrome, glaucoma, cataract, diabetic vitreopathy, and possibly macular degeneration. Systemic conditions such as diabetes and possibly Alzheimer's disease can potentially be detected early via ocular tissues. The current state of development of these techniques for application to ophthalmic research and ultimately clinical practice is reviewed.
Latch and hot-electron gate current in accumulation-mode SOI p-MOSFET's (1994)

Simultaneous measurements of drain and gate currents in short-channel accumulation-mode SOI p-MOSFET'MOs demonstrate that a latch mechanism may occur in these devices and induce an anomalous behavior of the hot-electron gate current: distortion of I/sub g/(V/sub g/) curves, hysteresis and excessively high gate current values. 2-D MEDICI simulations based on the lucky-electron model qualitatively reproduce the measurements in the latch regime, and explain the unusual gate current dependence on drain and gate biases. The results are of relevance for reliability and modeling issues.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Isomerization and Racemization of Menthols (1963)

Menthols were converted to Δ3-menthone enol acetate (VII) via menthones having only one asymmetric carbon atom. It was shown that the optical rotation of menthone enol acetate was proportional to the optical purity of starting menthols. Optical purity of original menthol could, therefore, be determined by optical rotation of menthone enol acetate derived from.
A Monolithic CMOS 2368&lt;tex&gt;$pm$&lt;/tex&gt;30 MHz Transformer Based&lt;tex&gt;$Q$&lt;/tex&gt;-Enhanced Series-C Coupled Resonator Bandpass Filter (2006)

A three-pole 0.1 dB ripple Chebyshev series-C coupled resonator bandpass filter with transformer-based Q-enhancement is presented. This Q-enhancement technique compensates resonator loss and produces a flat passband response with low insertion loss. The compensation scheme uses frequency-dependent negative resistance to compensate frequency-dependent inductor losses, avoiding passband distortion, which is a problem with cross-coupled negative resistance circuits. Fabricated in 0.18 /spl mu/m CMOS, the measured filter center frequency is 2368 MHz with a 60 MHz (3 dB) bandwidth, including probe pad and connecting trace parasitic losses. The filter draws 5.84 mA at 1.5 V, and the die area is 1.5 mm/spl times/1.5 mm.